bioRxiv directory

Willis, K. A.; Purvis, J. H.; Myers, E. D.; Aziz, M. M.; Karabayir, I.; Klazer Gomes, C. K.; Peters, B. M.; Akbilgic, O.; Talati, A. J.; Pierre, J. F.

10.1101/621235 — microbiology — Posted on 2019-04-30

13 The splicing factor hnRNP M is a critical regulator of innate immune gene expression in macrophages

West, K. O.; Scott, H. M.; Torres-Odio, S.; West, A. P.; Patrick, K.; Watson, R. O.

10.1101/617043 — immunology — Posted on 2019-04-30

14 ThermoRawFileParser: modular, scalable and cross-platform RAW file conversion

Hulstaert, N.; Sachsenberg, T.; Walzer, M.; Barsnes, H.; Martens, L.; Perez-Riverol, Y.

10.1101/622852 — bioinformatics — Posted on 2019-04-30

15 Impoverished auditory cues limit engagement of brain networks controlling spatial selective attention

Deng, Y.; Choi, I.; Shinn-Cunningham, B. G.; Baumgartner, R.

10.1101/533117 — neuroscience — Posted on 2019-04-30

16 Testing pleiotropy vs. separate QTL in multiparental populations

Boehm, F. J.; Chesler, E. J.; Yandell, B. S.; Broman, K. W.

10.1101/550939 — genetics — Posted on 2019-04-30

17 1D MinION sequencing for large-scale species discovery: 7000 scuttle flies (Diptera: Phoridae) from one site in Kibale National Park (Uganda) revealed to belong to >650 species

Srivathsan, A.; Hartop, E.; Puniamoorthy, J.; Lee, W. T.; Kutty, S. N.; Kurina, O.; Meier, R.

10.1101/622365 — evolutionary biology — Posted on 2019-04-30

18 Prevalence of pulmonary tuberculosis among patients presenting with cough of any duration in Addis Ababa, Ethiopia

Woldekiros, A. N.; Legesse, M.; Belay, M.; Medhin, G.; Mihret, A.; Ayalew, S.; Aynye Negesse, Dr Mulugeta Belay, Dr Girmay Medhin,

10.1101/622464 — epidemiology — Posted on 2019-04-30

19 Theory of cyborg: a new approach to fish locomotion control

Jamali, M.; Jamali, Y.; Golshani, M.

10.1101/621839 — bioengineering — Posted on 2019-04-30

20 Spatial and temporal alterations in protein structure by EGF regulate cryptic cysteine oxidation

Behring, J. B.; van der Post, S.; Mooradian, A. D.; Egan, M. J.; Zimmerman, M. I.; Clements, J. L.; Bowman, G. R.; Held, J. M.

10.1101/624304 — biochemistry — Posted on 2019-04-30

21 Molecular signatures of non-typeable Haemophilus influenzae lung adaptation in paediatric chronic lung disease

Aziz, A.; Sarovich, D. S.; Nosworthy, E.; Beissbarth, J.; Chang, A. B.; Smith-Vaughan, H.; Price, E. P.; Harris, T. M.

10.1101/614214 — microbiology — Posted on 2019-04-30

22 Mosaic evolution, constraint, and constructional opportunity in great apes

Parins-Fukuchi, C.

10.1101/622134 — evolutionary biology — Posted on 2019-04-30

23 Error, noise and bias in de novo transcriptome assemblies

Freedman, A. H.; Clamp, M.; Sackton, T. B.

10.1101/585745 — bioinformatics — Posted on 2019-04-30

24 Tendon response to matrix unloading is determined by the patho-physiological niche

Wunderli, S. L.; Blache, U.; Beretta Piccoli, A.; Niederoest, B.; Holenstein, C. N.; Passini, F.; Silvan, U.; Bundgaard, L.; auf dem Keller, U.; Snedeker, J. G.

10.1101/620534 — molecular biology — Posted on 2019-04-30

25 Fission yeast TRP channel Pkd2p localizes to the cleavage furrow and regulates cell separation during cytokinesis

Morris, Z.; Sinha, D.; Poddar, A.; Morris, B.; Chen, Q.

10.1101/316380 — cell biology — Posted on 2019-04-30

26 Glutamine Synthetase-1 induces autophagy-lysosomal degradation of huntingtin aggregates and ameliorates animal motility in a Drosophila model for Huntington’s disease

Vernizzi, L.; Paiardi, C.; Licata, G.; Vitali, T.; Santarelli, S.; Raneli, M.; Manelli, V.; Rizzetto, M.; Gioria, M.; Pasini, M. E.; Grifoni, D.; Vanoni, M. A.; Gellera, C.; Taroni, F.; Bellosta, P.

10.1101/618629 — cell biology — Posted on 2019-04-30

27 The number of k-mer matches between two DNA sequences as a function of k

Röhling, S.; Dencker, T.; Morgenstern, B.

10.1101/527515 — bioinformatics — Posted on 2019-04-30

28 Redistribution of NORTIA in response to pollen tube arrival facilitates fertilization in Arabidopsis thaliana

Yuan, J.; Ju, Y.; Jones, D. S.; Zhang, W.; Lucca, N.; Staiger, C. J.; Kessler, S. A.

10.1101/621599 — plant biology — Posted on 2019-04-30

29 A Spiking Neuron and Population Model based on the Growth Transform Dynamical System

Gangopadhyay, A.; Mehta, D.; Chakrabartty, S.

10.1101/523944 — neuroscience — Posted on 2019-04-30

30 Epigenetic bookmarking of H2S exposure in Caenorhabditis elegans

Fawcett, E. M.; Johnson, J. K.; Braden, C.; Garcia, E. M.; Miller, D. L.

10.1101/619734 — genetics — Posted on 2019-04-30

31 Marker subset selection and decision support range identification for acute myeloid leukemia classification model development with multiparameter flow cytometry

Choi, J.-S.; Nguyen, N. T.; Byun, H.-G.; Song, J.; Yoon, T. H.

10.1101/621797 — bioinformatics — Posted on 2019-04-30

32 Dengue antigenic relationships predict evolutionary dynamics

Bell, S. M.; Katzelnick, L.; Bedford, T.

10.1101/432054 — evolutionary biology — Posted on 2019-04-30

33 Multi-stage models for the failure of complex systems, cascading disasters, and the onset of disease

Webster, A. J.

10.1101/476242 — cancer biology — Posted on 2019-04-30

34 Structure of the tripartite motif of KAP1/TRIM28 identifies molecular interfaces required for transcriptional silencing of retrotransposons

Stoll, G. A.; Oda, S.-i.; Chong, Z.-S.; Yu, M.; McLaughlin, S. H.; Modis, Y.

10.1101/505677 — biochemistry — Posted on 2019-04-30

35 Tractostorm: Rater reproducibility assessment in tractography dissection of the pyramidal tract

Rheault, F.; De Benedictis, A.; Daducci, A.; Maffei, C.; Tax, C. M. W.; Romascano, D.; Caverzasi, E.; Morency, F. C.; Corrivetti, F.; Pestilli, F.; Girard, G.; Theaud, G.; Zemmoura, I.; Hau, J.; Glavin, K.; Jordan, K. M.; Pomiecko, K.; Chamberland, M.; Barakovic, M.; Goyette, N.; Poulin, P.; Chenot, Q.; Panesar, S. S.; Sarubbo, S.; Petit, L.; Descoteaux, M.

10.1101/623892 — neuroscience — Posted on 2019-04-30

36 Alternate subunit assembly diversifies the function of a bacterial toxin

Galan, J. E.; Fowler, C.; Stack, G.; Xiao, X.; Lara-Tejero, M.

10.1101/624130 — microbiology — Posted on 2019-04-30

37 Deep sequencing of 3 cancer cell lines on 2 sequencing platforms

Arora, K.; Shah, M.; Johnson, M.; Sanghvi, R.; Shelton, J.; Nagulapalli, K.; Oschwald, D. M.; Zody, M. C.; Germer, S.; Jobanputra, V.; Carter, J.; Robine, N.

10.1101/623702 — genomics — Posted on 2019-04-30

38 Impulse responses reveal unimodal and bimodal access to visual and auditory working memory

Wolff, M. J.; Kandemir, G.; Stokes, M. G.; Akyurek, E. G.

10.1101/623835 — neuroscience — Posted on 2019-04-30

39 Lipocalin-2 is a Sensitive and Specific Marker of Bacterial Infection in Children

Herberg, J.; Huang, H.; Thezenas, M. L.; Janes, V.; Carter, M.; Gormley, S.; Hamilton, M. S.; Kessler, B.; Levin, M.; Casals-Pascual, C.

10.1101/623819 — microbiology — Posted on 2019-04-30

40 Centrosome amplification favours survival and impairs ovarian cancer progression

Morretton, J.-P.; Herbette, A.; Cosson, C.; Mboup, B.; Latouche, A.; Gestraud, P.; Popova, T.; Stern, M.-H.; Nemati, F.; Decaudin, D.; Bataillon, G.; Becette, V.; Meseure, D.; Nicolas, A.; Mariani, O.; Bonneau, C.; Barbazan, J.; Vincent-Salomon, A.; Mechta-Grigoriou, F.; Roman Roman, S.; Rouzier, R.; Sastre-Garau, X.; Goundiam, O.; Basto, R.

10.1101/623983 — cancer biology — Posted on 2019-04-30

41 A transient time window for early predispositions in newborn chicks

Versace, E.; Ragusa, M.; Vallortigara, G.

10.1101/623439 — animal behavior and cognition — Posted on 2019-04-30

42 JASPer controls interphase histone H3S10 phosphorylation by chromosomal kinase JIL-1 in Drosophila

Albig, C.; Wang, C.; Dann, G. P.; Wojcik, F.; Schauer, T.; Krause, S.; Maenner, S.; Cai, W.; Li, Y.; Girton, J.; Muir, T. W.; Johansen, J.; Johansen, K. M.; Becker, P. B.; Regnard, C.

10.1101/624023 — molecular biology — Posted on 2019-04-30

43 Alternate subunit assembly diversifies the function of a bacterial toxin

Galan, J. E.; Fowler, C.; Stack, G.; Xiao, X.; Lara-Tejero, M.

10.1101/624130 — microbiology — Posted on 2019-04-30

44 High-speed volumetric fluorescein angiography (vFA) by oblique scanning laser ophthalmoscopy in mouse retina

Song, W.; Zhou, L.; Yi, J.

10.1101/621664 — bioengineering — Posted on 2019-04-30

45 F-actin patches associated with glutamatergic synapses control positioning of dendritic lysosomes

van Bommel, B.; Konietzny, A.; Kobler, O.; Baer, J.; Mikhaylova, M.

10.1101/624221 — neuroscience — Posted on 2019-04-30

46 Cell-to-cell Mathematical modeling of arrhythmia phenomena in excitable media

Lopez, G.

10.1101/624247 — cell biology — Posted on 2019-04-30

47 IL-1RA controls the development of esophageal cancer by inhibition of VEGF via PI3K/NF-κB signaling pathway

SHEN, Z.; Yu, S.; Gao, L.; Liu, Z.; Zhang, P.; Chai, T.; Chen, S.; Kang, M.

10.1101/623637 — cancer biology — Posted on 2019-04-30

48 The effect of phosphatidylserine on the membrane insertion of the cancer-targeting ATRAM peptide is defined by its non-inserting end

Nguyen, V. P.; Dixson, A. C.; Barrera, F. N.

10.1101/623967 — biophysics — Posted on 2019-04-30

49 Developmental exposure to perfluorooctane sulfononate (PFOS) and perfluorooctanoic acid (PFOA) selectively decreases brain dopamine levels in northern leopard frogs

Foguth, R. M.; Flynn, R. W.; de Perre, C.; Lee, L. S.; Sepulveda, M. S.; Cannon, J.

10.1101/623900 — pharmacology and toxicology — Posted on 2019-04-30

50 Targeted photostimulation uncovers circuit motifs supporting short-term memory

Daie, K.; Svoboda, K.; Druckmann, S.

10.1101/623785 — neuroscience — Posted on 2019-04-30

51 A flexible and generalizable model of online latent-state learning

Cochran, A. L.; Cisler, J. M.

10.1101/443234 — neuroscience — Posted on 2019-04-30

52 Kinesin-1 and dynein use distinct mechanisms to bypass obstacles

Ferro, L. S.; Can, S.; Turner, M. A.; Elshenawy, M. M.; Yildiz, A.

10.1101/624056 — biophysics — Posted on 2019-04-30

53 A methodology for morphological feature extraction and unsupervised cell classification

Bhaskar, D.; Lee, D.; Knutsdottir, H.; Tan, C.; Zhang, M.; Dean, P.; Roskelley, C.; Edelstein-Keshet, L.

10.1101/623793 — bioinformatics — Posted on 2019-04-30

54 Comparison of vibrotactile and joint-torque feedback in a myoelectric upper-limb prosthesis

Thomas, N.; Ung, G.; McGarvey, C.; Brown, J.

10.1101/623926 — bioengineering — Posted on 2019-04-30

55 Water for sterol: an unusual mechanism of sterol egress from a StARkin domain

Khelashvili, G.; Pandey, K.; Chauhan, N.; Eliezer, D.; Menon, A. K.

10.1101/623777 — biochemistry — Posted on 2019-04-30

56 Toggling Geobacter sulfurreducens metabolic state reveals hidden behaviour and expanded applicability to sustainable energy applications

Zarabadi, M. P.; Charette, S.; Greener, J.

10.1101/623652 — synthetic biology — Posted on 2019-04-30

57 Altered actin filament dynamics in the Drosophila mushroom bodies lead to fast acquisition of alcohol consumption preference.

Butts, A. R.; Ojelade, S. A.; Seguin, A.; Merrill, C. B.; Rodan, A. R.; Rothenfluh, A.

10.1101/623991 — neuroscience — Posted on 2019-04-30

58 A role for phagocytosis in inducing cell death during thymocyte negative selection

Kurd, N. S.; Lutes, L. K.; Yoon, J.; Dzhagalov, I. L.; Hoover, A.; Robey, E. A.

10.1101/624148 — immunology — Posted on 2019-04-30

59 Genome-scale comparative analysis for host resistance against sea lice between Atlantic salmon and rainbow trout

Caceres, P.; Barria, A.; Christensen, K. A.; Bassini, L.; Correa, K.; Lhorente, J. P.; Yanez, J. M.

10.1101/624031 — genomics — Posted on 2019-04-30

60 Mutations that improve the efficiency of a weak-link enzyme are rare compared to adaptive mutations elsewhere in the genome

Morgenthaler, A. B.; Kinney, W. R.; Ebmeier, C. C.; Walsh, C. M.; Snyder, D. J.; Cooper, V. S.; Old, W. M.; Copley, S. D.

10.1101/624205 — evolutionary biology — Posted on 2019-04-30

61 Direct monitoring of cAMP at the cardiac ryanodine receptor using a novel targeted fluorescence biosensor mouse

Berisha, F.; Goetz, K.; Wegener, J.; Jungen, C.; Pape, U.; Kraft, A.; Warnke, S.; Lindner, D.; Westermann, D.; Blankenberg, S.; Meyer, C.; Hasenfuss, G.; Lehnart, S.; Nikolaev, V.

10.1101/623934 — cell biology — Posted on 2019-04-30

62 Multi-walled carbon nanotubes/nano-Ag-TiO2 membrane DNA electrochemical biosensor

Smith, J.; Zheng, Z.; Schultz, L.

10.1101/618488 — bioengineering — Posted on 2019-04-30

63 Unveiling two new trichome-specific promoters of interest for metabolic engineering in Nicotiana tabacum

Pottier, M.; Laterre, R.; Van Wessem, A.; M. Ramirez, A.; Herman, X.; Boutry, M.; Hachez, C.

10.1101/620021 — plant biology — Posted on 2019-04-30

64 Identification of a role for an E6-like 1 gene in early pollen-stigma interactions in Arabidopsis thaliana

Doucet, J.; Truong, C.; Frank-Webb, E.; Lee, H. K.; Daneva, A.; Gao, Z.; Nowack, M.; Goring, D.

10.1101/623686 — plant biology — Posted on 2019-04-30

65 Emotional valence modulates the topology of the parent-infant inter-brain network

Covarrubias, L. S.; Noreika, V.; Georgieva, S.; Clackson, K.; Wass, S.; Leong, V.

10.1101/623355 — neuroscience — Posted on 2019-04-30

66 A novel mechanism for amplification of sensory responses by the amygdala-TRN projections.

Aizenberg, M.; Rolon Martinez, S.; Pham, T.; Rao, W.; Haas, J.; Geffen, M. N.

10.1101/623868 — neuroscience — Posted on 2019-04-30

67 Synaptic mechanisms of context-dependent sensory responses in the hippocampus

Zhao, X.; Wang, Y.; Spruston, N.; Magee, J. C.

10.1101/624262 — neuroscience — Posted on 2019-04-30

68 Hdac3, Setdb1, and Kap1 mark H3K9me3/H3K14ac bivalent regions in young and aged liver.

Price, A. J.; Manjegowda, M. C.; Bochkis, I. M.

10.1101/623975 — genomics — Posted on 2019-04-30

69 Parasite-induced shifts in host movement may explain the transient coexistence of high- and low-pathogenic disease strains

Fofana, A. M.; Hurford, A.

10.1101/623660 — evolutionary biology — Posted on 2019-04-30

70 Regulation of Cyclin E by transcription factors of the naïve pluripotency network in mouse embryonic stem cells

Gonnot, F.; Langer, D.; Bourillot, P.-Y.; Doerflinger, N.; Savatier, P.

10.1101/623884 — cell biology — Posted on 2019-04-30

71 Multi-scale Computational Modeling of Tubulin-Tubulin Lateral Interaction

Hemmat, M.; Castle, B. T.; Sachs, J. N.; Odde, D. J.

10.1101/624213 — biophysics — Posted on 2019-04-30

72 Conformational Flexibility of p150Glued(1-191) Subunit of Dynactin Assembled with Microtubules

Guo, C.; Williams, J. C.; Polenova, T.

10.1101/623751 — biophysics — Posted on 2019-04-30

73 RSAT Var-tools: an accessible and flexible framework to predict the impact of regulatory variants on transcription factor binding

Santana-Garcia, W.; Rocha-Acevedo, M.; Ramirez, L.; Mbouamboua, Y.; Thieffry, D.; Thomas-Chollier, M.; Contreras-Moreira, B.; van Helden, J.; Medina-Rivera, A.

10.1101/623090 — bioinformatics — Posted on 2019-04-30

74 Uncovering and characterizing splice variants associated with survival in lung cancer patients

West, S.; Kumar, S.; Batra, S. K.; Ali, H.; Ghersi, D.

10.1101/623876 — bioinformatics — Posted on 2019-04-30

75 treeSeg: Testing for Dependence on Tree Structures

Behr, M.; Ansari, M. A.; Munk, A.; Holmes, C.

10.1101/622811 — bioinformatics — Posted on 2019-04-30

76 Behavioural responses to video and live presentations of females reveal a dissociation between performance and motivational aspects of birdsong

James, L. S.; Fan, R.; Sakata, J. T.

10.1101/624015 — animal behavior and cognition — Posted on 2019-04-30

77 Parameter inference in dynamical systems with co-dimension 1 bifurcations

Roesch, E.; Stumpf, M. P. H.

10.1101/623413 — systems biology — Posted on 2019-04-30

78 Are place cells just memory cells? Memory compression leads to spatial tuning and history dependence

Benna, M. K.; Fusi, S.

10.1101/624239 — neuroscience — Posted on 2019-04-30

79 Context-dependent probability estimation and its neurocomputational substrates

Lin, W.-H.; Gardner, J.; Wu, S.-W.

10.1101/624163 — neuroscience — Posted on 2019-04-30

80 New Insights into the Genetic Diversity of the Bacterial Plant Pathogen ‘Candidatus Liberibacter solanacearum’ as Revealed by a New Multilocus Sequence Analysis Scheme

Hajri, A.; Cousseau-Suhard, P.; Gentit, P.; Loiseau, M.

10.1101/623405 — microbiology — Posted on 2019-04-30

81 Pediatric and adult-onset HCM mutations in the myosin motor domain have similar properties

Vera, C. D.; Johnson, C. A.; Walklate, J.; Adhikari, A.; Ujfalusi, Z.; Svicevic, M.; Mijailovich, S.; Combs, A.; Langer, S. J.; Ruppel, K. M.; Spudich, J. A.; Leinwand, L. A.; Geeves, M. A.

10.1101/622738 — biophysics — Posted on 2019-04-30

82 More accurate transcript assembly via parameter advising

DeBlasio, D.; Kim, K.; Kingsford, C.

10.1101/342865 — bioinformatics — Posted on 2019-04-30

83 Preparation and optimization of MEPEG-PLGA nanoparticles for gene delivery

Smith, J.; Monash, L.

10.1101/624254 — bioengineering — Posted on 2019-04-30

84 Polyubiquitin-dependent recruitment of NEMO/IKKγ into T cell receptor signaling microclusters

DeRiso, E. A.; Szymczak-Workman, A. L.; Montecalvo, A.; Murphy, J. M.; Seminario, M.-C.; Kane, L. P.; Bunnell, S. C.

10.1101/617126 — immunology — Posted on 2019-04-30

85 Reconstructing Phylogenetic Relationships Based On Repeat Sequence Similarities

Vitales, D.; Garcia, S.; Dodsworth, S.

10.1101/624064 — evolutionary biology — Posted on 2019-04-30

86 The Role of Sevenless in Drosophila R7 Photoreceptor Specification

Tomlinson, A.; Mavromatakis, Y. E.; Arias, R.

10.1101/624155 — developmental biology — Posted on 2019-04-30

87 Modification of an atypical clathrin-independent AP-2 adaptin complex of Plasmodium falciparum reduces susceptibility to artemisinin

Henrici, R. C.; Edwards, R. L.; Zoltner, M.; van Schalkwyk, D. A.; Hart, M. N.; Mohring, F.; Moon, R. W.; Nofal, S. D.; Patel, A.; Flueck, C.; Baker, D. A.; Odom John, A.; Field, M. C.; Sutherland, C. J.

10.1101/621078 — microbiology — Posted on 2019-04-30

88 Renal and Renal Sinus Fat Volumes as Quantified by Magnetic Resonance Imaging in Subjects with Prediabetes, Diabetes, and Normal Glucose Tolerance.

Notohamiprodjo, M.; Goepfert, M.; Will, S.; Lorbeer, R.; Schick, F.; Rathmann, W.; Martirosian, P.; Peters, A.; Müller-Peltzer, K.; Helck, A.; Rospleszcz, S.; Bamberg, F.

10.1101/620146 — epidemiology — Posted on 2019-04-30

89 Persistence of learning-induced synapses depends on neurotrophic-priming of glucocorticoid receptors

Arango-Lievano, M.; Borie, A. M.; Dromard, Y.; Murat, M.; Desarmenien, M. G.; Garabedian, M. J.; Jeanneteau, f.

10.1101/623389 — neuroscience — Posted on 2019-04-30

90 Recombining your way out of trouble: The genetic architecture of hybrid fitness under environmental stress

Zhang, Z.; Bendixsen, D.; Janzen, T.; Nolte, A.; Greig, D.; Stelkens, R.

10.1101/622845 — evolutionary biology — Posted on 2019-04-30

91 The neuronal calcium sensor Synaptotagmin-1 and SNARE proteins cooperate to dilate fusion pores mechanically

Wu, Z.; Dharan, N.; Thiyagarajan, S.; O'Shaughnessy, B.; Karatekin, E.

10.1101/623827 — biophysics — Posted on 2019-04-30

92 An elastic-net logistic regression approach to generate classifiers and gene signatures for types of immune cells and T helper cell subsets

Torang, A.; Gupta, P.; Klinke, D. J.

10.1101/623082 — bioinformatics — Posted on 2019-04-30

93 A web-based platform of nucleotide sequence alignments of plants

Santos, C.; Carneiro, J.; Pereira, F.

10.1101/617035 — bioinformatics — Posted on 2019-04-30

94 Isolated occurrences of membrane perturbation by mechanosensing from weakly aggregating silver nanoparticles

Arribas Perez, M.; Moriones, O. H.; Bastus, N. G.; Puntes, V.; Nelson, A.; Beales, P. A.

10.1101/623678 — biophysics — Posted on 2019-04-30

95 Separating distinct structures of multiple macromolecular assemblies from cryo-EM projections

Verbeke, E. J.; Zhou, Y.; Horton, A. P.; Mallam, A. L.; Taylor, D. W.; Marcotte, E. M.

10.1101/611566 — biochemistry — Posted on 2019-04-30

96 Within-population genome size variation is mediated by multiple genomic elements that segregate independently during meiosis

Stelzer, C.-P.; Pichler, M.; Stadler, P.; Hatheuer, A.; Riss, S.

10.1101/623470 — evolutionary biology — Posted on 2019-04-30

97 Predicting the time of entry of nanoparticles in cellular membranes

Liu, C.; Elvati, P.; Majumder, S.; Wang, Y.; Liu, A.; Violi, A.

10.1101/619221 — biophysics — Posted on 2019-04-30

98 C9orf72 dipeptide repeats inhibit UPF1-mediated RNA decay independent of stress granule formation

Sun, Y.; Eshov, A.; Guo, J. U.

10.1101/623769 — molecular biology — Posted on 2019-04-30

99 Renal and Renal Sinus Fat Volumes as Quantified by Magnetic Resonance Imaging in Subjects with Prediabetes, Diabetes, and Normal Glucose Tolerance.

Notohamiprodjo, M.; Goepfert, M.; Will, S.; Lorbeer, R.; Schick, F.; Rathmann, W.; Martirosian, P.; Peters, A.; Müller-Peltzer, K.; Helck, A.; Rospleszcz, S.; Bamberg, F.

10.1101/620146 — epidemiology — Posted on 2019-04-30

100 Transcriptional programs define intratumoral heterogeneity of Ewing sarcoma at single cell resolution

Aynaud, M.-M.; Mirabeau, O.; Gruel, N.; Grossetete-Lalami, S.; Boeva, V.; Durand, S.; Surdez, D.; Saulnier, O.; Zaidi, S.; Gribkova, S.; Kairov, U.; Raynal, V.; Tirode, F.; Grunewald, T. G.; Bohec, M.; Baulande, S.; Janoueix-Lerosey, I.; Vert, J.-P.; Barillot, E.; Delattre, O.; Zinovyev, A.

10.1101/623710 — cancer biology — Posted on 2019-04-30

101 Arp2/3 complex-driven spatial patterning of the B cell receptor (BCR) enhances immune synapse formation, BCR signaling, and cell activation

Bolger-Munro, M.; Choi, K.; Scurll, J.; Abraham, L.; Chappell, R.; Sheen, D.; Dang-Lawson, M.; Wu, X.; Priatel, J. J.; Coombs, D.; Hammer, J. A.; Gold, M. R.

10.1101/490698 — immunology — Posted on 2019-04-30

102 4q-D4Z4 chromatin architecture regulates the transcription of muscle atrophic genes in FSHD

Cortesi, A.; Pesant, M.; Sinha, S.; Marasca, F.; Sala, E.; Gregoretti, F.; Antonelli, L.; Oliva, G.; Chiereghin, C.; Solda, G.; Bodega, B.

10.1101/623363 — genomics — Posted on 2019-04-30

103 Trapping a somatic endogenous retrovirus into a germline piRNA cluster immunizes the germline against further invasion

Duc, C.; Yoth, M.; Jensen, S.; Mouniee, N.; Bergman, C.; Vaury, C.; Brasset, E.

10.1101/510016 — genetics — Posted on 2019-04-30

104 Highly diverse fungal communities in carbon-rich aquifers of two contrasting lakes in Northeast Germany

Perkins, A.; Ganzert, L.; Rojas-Jimenez, K.; Fonvielle, J.; Hose, G.; Grossart, H.-P.

10.1101/623272 — microbiology — Posted on 2019-04-30

105 Induction via Functional Protein Stabilization of Hepatic Cytochromes P450 upon gp78/ Autocrine Motility Factor Receptor (AMFR) Ubiquitin E3-ligase Genetic Ablation in Mice: Therapeutic and Toxicological Relevance.

Kwon, D.; Kim, S.-m.; Jacob, P.; Liu, Y.; Correia, M. A.

10.1101/623041 — pharmacology and toxicology — Posted on 2019-04-30

106 Free circular introns with an unusual branchpoint in neuronal projections

Eddy, S. R.; Saini, H.; Moore, M. J.; Bicknell, A. A.

10.1101/623447 — cell biology — Posted on 2019-04-30

107 Hierarchical Network Exploration using Gaussian MixtureModels

Mathews, J.; Nadeem, S.; Pouryahya, M.; Belkhatir, Z.; Deasy, J. O.; Tannenbaum, A.

10.1101/623157 — bioinformatics — Posted on 2019-04-30

108 Larval growth and survival in Indian Butter Catfish, Ompok bimaculatus (Bloch): effect of light intensity and photoperiod

Arambam, K.; Biswas, P.; Singh, S. K.; Patel, A. B.; Jena, A. K.; Singh, R. D.; Pandey, P. K.

10.1101/623462 — animal behavior and cognition — Posted on 2019-04-30

109 Acquired loss of cardiac vagal activity is associated with myocardial injury in patients undergoing non-cardiac surgery: prospective observational mechanistic cohort study.

ACKLAND, G.; May, S.; X-MINS Study Investigators,

10.1101/623165 — physiology — Posted on 2019-04-30

110 Interspecies interactions in a model, mixed-species biofilm are determined by physiological traits and environmental factors

Booth, S.; Rice, S.

10.1101/623017 — microbiology — Posted on 2019-04-30

111 Long noncoding RNA AVAN promotes antiviral innate immunity by interacting with TRIM25 and enhancing the transcription of FOXO3a

Lai, C.; liu, l.; liu, q.; cheng, s.; wang, k.; zhao, l.; xia, m.; gu, h.; wang, c.; duan, y.; zhao, z.; zhang, l.; liu, z.; Luo, J.; Song, J.; Yang, P.; Chen, R.; Wang, X.

10.1101/623132 — immunology — Posted on 2019-04-30

112 BONE FRACTURE DETECTION BY ELECTRICAL BIOIMPEDANCE: FIRST NON-INVASIVE MEASUREMENTS IN EX-VIVO MAMMALIAN FEMUR

Dell'Osa, A. H.; Concu, A.; Dobarro, F. R.; Felice, J. C.

10.1101/622936 — bioengineering — Posted on 2019-04-30

113 Stimulation-artifact-free, high-spatiotemporal-resolution in vivo optoEphys with μLED optoelectrodes

Kim, K.; Vöröslakos, M.; Seymour, J. P.; Wise, K. D.; Buzsaki, G.; Yoon, E.

10.1101/622670 — bioengineering — Posted on 2019-04-30

114 Bayesian inference of distributed time delay in transcriptional and translational regulation

Choi, B.; Cheng, Y.-Y.; Cinar, S.; Ott, W.; Bennett, M. R.; Josic, K.; Kim, J. K.

10.1101/608596 — systems biology — Posted on 2019-04-30

115 Distentangling the systems contributing to changes in learning during adolescence

Master, S. L.; Eckstein, M. K.; Gotlieb, N.; Dahl, R.; Wilbrecht, L.; Collins, A. G.

10.1101/622860 — neuroscience — Posted on 2019-04-30

116 Acquisition of Temporal Order Involves a Reverberating Network in Hippocampal Field CA3

Gunn, B. G.; Cox, B. M.; Cox, C. D.; Le, A. A.; Inchishian, V. C.; Gall, C. M.; Lynch, G.

10.1101/623025 — neuroscience — Posted on 2019-04-30

117 Extrinsic noise and heavy-tailed laws in gene expression

Ham, L.; Brackston, R. D.; Stumpf, M. P. H.

10.1101/623371 — systems biology — Posted on 2019-04-30

118 Cyclosporine A Directly Affects Human and Mouse B cell Migration in vitro by Disrupting a HIF-1α Dependent, O2 Sensing, Molecular Switch

Hilchey, S. P.; Palshikar, M. G.; Li, D.; Garigen, J.; Cipolla, V.; Thakar, J.; Zand, M. S.

10.1101/622514 — immunology — Posted on 2019-04-30

119 Dynamics of adaptation in an anisotropic phenotype-fitness landscape

Hamel, F.; Lavigne, F.; Martin, G.; Roques, L.

10.1101/623330 — evolutionary biology — Posted on 2019-04-30

120 ThermoRawFileParser: modular, scalable and cross-platform RAW file conversion

Hulstaert, N.; Sachsenberg, T.; Walzer, M.; Barsnes, H.; Martens, L.; Perez-Riverol, Y.

10.1101/622852 — bioinformatics — Posted on 2019-04-30

121 Differences in the Electrical Impedance Spectroscopy variables between right and left forearms in healthy people: a non invasive method to easy monitoring structural changes in human limbs?

Dell'Osa, A. H.; Gel, M.; Concu, A.; Fois, A.; Mela, Q.; Loviselli, A.; Velluzzi, F.

10.1101/622944 — bioengineering — Posted on 2019-04-30

122 His bundle has shorter chronaxie than adjacent ventricular myocardium: Implications for pacemaker programming.

Jastrzebski, M.; Moskal, P.; Bednarek, A.; Kielbasa, G.; Vijayaraman, P.; Czarnecka, D.

10.1101/623348 — physiology — Posted on 2019-04-30

123 The neural basis for response latency in a sensory-motor behavior

Lee, J.; Darlington, T. R.; Lisberger, S. G.

10.1101/623256 — neuroscience — Posted on 2019-04-30

124 Phase-specific microstimulation in brain-machine interface setting differentially modulates beta oscillations and affects behavior

Peles, O.; Werner-Reiss, U.; Bergman, H.; Israel, Z.; Vaadia, E.

10.1101/622787 — neuroscience — Posted on 2019-04-30

125 Contrasting biogeographic patterns of bacterial and archaeal diversity in the top- and subsoils of temperate grasslands

Liu, N.; Hu, H.; Ma, W.; Deng, Y.; Liu, Y.; Hao, B.; Zhang, X.; Dimitrov, D.; Feng, X.; Wang, Z.

10.1101/623264 — microbiology — Posted on 2019-04-30

126 Parasitic worm product ES-62 promotes healthspan and lifespan in a mouse model of obesity-induced ageing

Crowe, J.; Lumb, F. E.; Doonan, J.; Tarafdar, A.; Pineda, M. A.; Hoskisson, P. A.; Babayan, S.; Selman, C.; Harnett, W.; Harnett, M. M.

10.1101/622753 — immunology — Posted on 2019-04-30

127 The ebb and flow of heteroplasmy during intra-species hybridization in Caenorhabditis briggsae

Adineh, S.; Ross, J.

10.1101/623207 — evolutionary biology — Posted on 2019-04-30

128 A Bayesian Nonparametric Approach to Discover Clinico-Genetic Associations across Cancer Types

Pradier, M. F.; Hyland, S. L.; Stark, S. G.; Lehmann, K.; Vogt, J. E.; Perez-Cruz, F.; Ratsch, G.

10.1101/623215 — bioinformatics — Posted on 2019-04-30

129 tRNAscan-SE 2.0: Improved Detection and Functional Classification of Transfer RNA Genes

Chan, P. P.; Lin, B. Y.; Mak, A. J.; Lowe, T. M.

10.1101/614032 — bioinformatics — Posted on 2019-04-30

130 Autoregulation of pre-mRNA processing for buffering noisy gene expression

Smith, M.; Ghusinga, K.; Singh, A.

10.1101/623181 — systems biology — Posted on 2019-04-30

131 Total RNA-sequencing reveals multi-level microbial community changes and functional responses to wood ash application in agricultural and forest soil

Bang-Andreasen, T.; Anwar, M. Z.; Lanzen, A.; Kjoller, R.; Ronn, R.; Ekelund, F.; Suhr Jacobsen, C.

10.1101/621557 — microbiology — Posted on 2019-04-30

132 Genomic islets in a sea of introgressions between sympatric species

Wang, X.; Guo, Z.; Xu, S.; Yang, M.; Chen, Q.; Li, S.; Zhong, C.; Duke, N. C.; He, Z.; Wu, C.-I.; Shi, S.

10.1101/622019 — evolutionary biology — Posted on 2019-04-30

133 Systematic sequencing of chloroplast transcript termini from Arabidopsis thaliana reveals >200 transcription initiation sites and the extensive imprints of RNA-binding proteins and secondary structures

Castandet, B.; Germain, A.; Hotto, A.; Stern, D.

10.1101/621938 — plant biology — Posted on 2019-04-30

134 Accurate ethnicity prediction from placental DNA methylation data

Yuan, V.; Price, E. M.; Del Gobbo, G. F.; Mostafavi, S.; Cox, B.; Binder, A. M.; Michels, K. B.; Marsit, C.; Robinson, W. P.

10.1101/618470 — genomics — Posted on 2019-04-30

135 Giraffe Translocation Population Viability Analysis

Lee, D. E.; Muller, Z.; Strauss, M.; Carter, K.; Scheijen, C.; Deacon, F.

10.1101/619114 — ecology — Posted on 2019-04-30

136 Fluorescent biosensor for real-time interaction dynamics of host proteins with HIV-1 capsid tubes

Lau, D.; Walsh, J.; Peng, W.; Shah, V.; Turville, S.; Jacques, D.; Böcking, T.

10.1101/619841 — biophysics — Posted on 2019-04-30

137 Competence of Corynebacterium glutamicum as a host for the production of type I polyketides

Kallscheuer, N.; Kage, H.; Milke, L.; Nett, M.; Marienhagen, J.

10.1101/622399 — bioengineering — Posted on 2019-04-30

138 Adaptive Bet-Hedging Revisited: Considerations of Risk and Time Horizon

Tal, O.; Tran, T. D.

10.1101/617084 — evolutionary biology — Posted on 2019-04-30

139 Genetic diversity and domestication of hazelnut (Corylus avellana) in Turkey

Helmstetter, A. J.; Oztolan-Erol, N.; Lucas, S. J.; Buggs, R. J. A.

10.1101/622027 — evolutionary biology — Posted on 2019-04-30

140 Phytolacca americana PaGT2 is an ambidextrous polyphenol glucosyltransferase

Maharjan, R.; Fukuda, Y.; Shimomura, N.; Nakayama, T.; Nakayama, T.; Hamada, H.; Inoue, T.; Ozaki, S.-i.

10.1101/620955 — biochemistry — Posted on 2019-04-30

141 Predicting and Designing therapeutics against the Nipah virus

Sen, N.; Kanitkar, T. R.; Roy, A. A.; Soni, N.; Amritkar, K.; Supekar, S.; Nair, S.; Singh, G.; Madhusudhan, M.

10.1101/623603 — bioinformatics — Posted on 2019-04-30

142 Stabilization of α-synuclein oligomers using formaldehyde

Reimer, L.; Ruesink, H.; Gregersen, E.; Moeller, A.; Betzer, C.; Jensen, P. H.

10.1101/623538 — neuroscience — Posted on 2019-04-30

143 Selective Brain Hypothermia Ameliorates Focal Cerebral Ischemia-Reperfusion Injury via Inhibiting Fis1 in Rats

yanan, T.; huailong, C.; xiaopeng, S.; weiwei, Q.; fei, S.; lixin, S.; xiaona, X.; gaofeng, Z.; mingshan, W.

10.1101/623611 — neuroscience — Posted on 2019-04-30

144 Characterization and function of medium and large extracellular vesicles from plasma and urine by surface antigens and Annexin V

Igami, K.; Uchiumi, T.; Ueda, S.; Kamioka, K.; Setoyama, D.; Gotoh, K.; Akimoto, M.; Matsumoto, S.; Kang, D.

10.1101/623553 — molecular biology — Posted on 2019-04-30

145 Effects of artificially introduced Enterococcus faecalis strains in experimental necrotizing enterocolitis

Grishin, A. V.; Delaplain, P. T.; Bell, B. A.; Wang, J.; Isani, M.; Zhang, E.; Gayer, C. P.; Ford, H. R.

10.1101/623512 — microbiology — Posted on 2019-04-30

146 Biofilm of Klebsiella pneumoniae minimize phagocytosis and cytokine expression by macrophage cell line

Rathore, S. S.; Cheepurupalli, L.; Gangwar, J.; Raman, T.; Ramakrishnan, J.

10.1101/623546 — immunology — Posted on 2019-04-30

147 Survey of intertidal ecosystem reveals a legacy of potentially toxic elements from industrial activity in the Skeena Estuary, British Columbia, Canada

Sizmur, T.; Campbell, L.; Dracott, K.; Jones, M.; O'Driscoll, N. J.; Gerwing, T.

10.1101/623587 — ecology — Posted on 2019-04-30

148 Human rDNA Copy Number Is Unstable in Metastatic Breast Cancers

Valori, V.; Tus, K.; Laukaitis, C.; Harris, D. T.; LeBeau, L.; Maggert, K. A.

10.1101/623595 — cancer biology — Posted on 2019-04-30

149 Feature-Specific Neural Reactivation during Episodic Memory

Bone, M. B.; Ahmad, F.; Buchsbaum, B. R.

10.1101/622837 — neuroscience — Posted on 2019-04-30

150 Drosophila insulin-like peptide 1 (DILP1) promotes organismal growth and catabolic energy metabolism during the non-feeding pupal stage

Liao, S.; Post, S.; Lehmann, P.; Veenstra, J. A.; Tatar, M.; Nassel, D. R.

10.1101/421669 — neuroscience — Posted on 2019-04-30

151 Glutamine Synthetase-1 induces autophagy-lysosomal degradation of Huntingtin aggregates and ameliorates animal motility in a Drosophila model for HD

Vernizzi, L.; Paiardi, C.; Licata, G.; Vitali, T.; Santarelli, S.; Raneli, M.; Manelli, V.; Rizzetto, M.; Gioria, M.; Pasini, M. E.; Grifoni, D.; Vanoni, M. A.; Gellera, C.; Taroni, F.; Bellosta, P.

10.1101/618629 — cell biology — Posted on 2019-04-30

152 simuG: a general-purpose genome simulator

Yue, J.-X.; Liti, G.

10.1101/491498 — bioinformatics — Posted on 2019-04-30

153 Development of PTSD-like behavior in adult mice after observing an acute traumatic event

Lee, R. X.; Stephens, G. J.; Kuhn, B.

10.1101/249870 — neuroscience — Posted on 2019-04-30

154 Molecular signatures of non-typeable Haemophilus influenzae lung adaptation in paediatric chronic lung disease

Aziz, A.; Sarovich, D. S.; Nosworthy, E.; Beissbarth, J.; Chang, A. B.; Smith-Vaughan, H.; Price, E. P.; Harris, T. M.

10.1101/614214 — microbiology — Posted on 2019-04-30

155 The ‘breakpoint’ in transmission for soil-transmitted helminths: dynamical behaviour near the equilibria and the impact of infected human migration

J. Hardwick, R.; Vegvari, C.; E. Truscott, J.; M. Anderson, R.

10.1101/619908 — epidemiology — Posted on 2019-04-30

156 Differential gene expression analysis reveals novel genes and pathways in pediatric septic shock patients

Mohammed, A.; Cui, Y.; Mas, V. R.; Kamaleswaran, R.

10.1101/611947 — bioinformatics — Posted on 2019-04-30

157 Early patterns of functional brain development associated with autism spectrum disorder in tuberous sclerosis complex.

Dickinson, A.; Varcin, K. J.; Sahin, M.; Nelson, C. A.; Jeste, S. S.

10.1101/578831 — neuroscience — Posted on 2019-04-30

158 Structural and Functional Characterization of G Protein-Coupled Receptors with Deep Mutational Scanning

Jones, E. M.; Lubock, N. B.; Venkatakrishnan, A.; Wang, J.; Tseng, A. M.; Paggi, J. M.; Latorraca, N. R.; Cancilla, D.; Satyadi, M.; Davis, J.; Mohan, M. B.; Dror, R. O.; Kosuri, S.

10.1101/623108 — molecular biology — Posted on 2019-04-30

159 Acetyl-CoA production by specific metabolites promotes cardiac repair after myocardial infarction via mediating histone acetylation

Lei, I.; Tian, S.; Gao, W.; Liu, L.; Guo, Y.; Wang, Z.

10.1101/622746 — cell biology — Posted on 2019-04-30

160 A doublecortin-domain protein of Toxoplasma and its orthologues bind to and modify the structure and organization of tubulin polymers

Leung, J. M.; Nagayasu, E.; Hwang, Y.-C.; Pierce, P.; Phan, I. Q.; Stacy, R.; Murray, J. M.; Hu, K.

10.1101/623140 — cell biology — Posted on 2019-04-30

161 Does a strong reduction of colony workforce affect the foraging strategy of a social pollinator?

Biella, P.; Tommasi, N.; Akter, A.; Guzzetti, L.; Klecka, J.; Sandionigi, A.; Labra, M.; Galimberti, A.

10.1101/622910 — ecology — Posted on 2019-04-29

162 Diverse conjugative elements silence natural transformation in Legionella species

Durieux, I.; Ginevra, C.; Attaiech, L.; Picq, K.; Juan, P.-A.; Jarraud, S.; Charpentier, X.

10.1101/623074 — microbiology — Posted on 2019-04-29

163 A new class of disordered elements controls DNA replication through initiator self-assembly

Parker, M. W.; Bell, M.; Mir, M.; Kao, J. A.; Darzacq, X.; Botchan, M. R.; Berger, J. M. M.

10.1101/623058 — biochemistry — Posted on 2019-04-29

164 Conformational catalysis of cataract-associated aggregation in a human eye lens crystallin occurs via interface stealing.

Serebryany, E.; Jacobs, W. M.; Razban, R.; Shakhnovich, E.

10.1101/601708 — biophysics — Posted on 2019-04-29

165 Dean flow assisted single cell and bead encapsulation for high performance single cell expression profiling

Li, L.; Wu, P.; Luo, Z.; Wang, L.; Ding, W.; Wu, T.; Chen, J.; He, J.; He, Y.; Wang, H.; Chen, Y.; Li, G.; Li, Z.; He, L.

10.1101/520858 — bioengineering — Posted on 2019-04-29

166 Pathogen evasion of chemokine response through suppression of CXCL10

Antonia, A. L.; Gibbs, K. D.; Trahair, E.; Pittman, K. J.; Schott, B. H.; Smith, J. S.; Rajagopal, S.; Thompson, J. W.; Reinhardt, R. L.; Ko, D. C.

10.1101/557876 — microbiology — Posted on 2019-04-29

167 The Maize LINC KASH AtSINE-like2 (MLKS2) gene encodes an ARM domain protein that tethers the nucleus to F-actin and is required for normal development and meiotic chromosome segregation

Gumber, H. K.; McKenna, J. F.; Tolmie, A. F.; Jalovec, A. M.; Kartick, A. C.; Graumann, K.; Bass, H. W.

10.1101/609594 — cell biology — Posted on 2019-04-29

168 Creating reproducible pharmacogenomic analysis pipelines

Mammoliti, A.; Smirnov, P.; Safikhani, Z.; Ba-Alawi, W.; Haibe-Kains, B.

10.1101/614560 — bioinformatics — Posted on 2019-04-29

169 UBR5 is a Novel E3 Ubiquitin Ligase involved in Skeletal Muscle Hypertrophy and Recovery from Atrophy

Seaborne, R. A.; Hughes, D. C.; Turner, D. C.; Owens, D. J.; Baehr, L. M.; Gorski, P.; Semenova, E. A.; Borisov, O. V.; Larin, A. K.; Popov, D. V.; Generozov, E. V.; Sutherland, H.; Ahmetov, I. I.; Jarvis, J. C.; Bodine, S. C.; Sharples, A. P.

10.1101/592980 — physiology — Posted on 2019-04-29

170 Integrated analysis of the miRNA-mRNA network associated with LMP1 gene in nasopharyngeal carcinoma

Yang, Y.; Liu, W.; Zhang, Y.; Wu, S.; Luo, B.

10.1101/615237 — microbiology — Posted on 2019-04-29

171 Longer is not always better: Optimizing barcode length for large-scale species discovery and identification

Yeo, D.; Srivathsan, A.; Meier, R.

10.1101/594952 — evolutionary biology — Posted on 2019-04-29

172 Control of glioblastoma differentiated-to-stem cell reprogramming by IRE1α/XBP1s signaling.

Doultsinos, D.; McMahon, M.; Voutetakis, K.; Obacz, J.; Pineau, R.; Jouan, F.; Le Reste, P.-J.; Obiedat, A.; Samal, J.; Patterson, J. B.; Zheng, Q.; Samali, A.; Pandit, A.; Tirosh, B.; Chatziioannou, A.; Chevet, E.; Avril, T.

10.1101/594630 — cancer biology — Posted on 2019-04-29

173 QTG-Finder: a machine-learning based algorithm to prioritize causal genes of quantitative trait loci in Arabidopsis and rice

Lin, F.; Fan, J.; Rhee, S. Y.

10.1101/484204 — systems biology — Posted on 2019-04-29

174 Consensus sequence design as a general strategy to create hyperstable, biologically active proteins

Sternke, M.; Tripp, K. W.; Barrick, D.

10.1101/466391 — biophysics — Posted on 2019-04-29

175 DLITE uses cell-cell interface movement to better infer cell-cell tensions

Vasan, R.; Maleckar, M. M.; Williams, C. D.; Rangamani, P.

10.1101/541144 — biophysics — Posted on 2019-04-29

176 Tibanna: software for scalable execution of portable pipelines on the cloud

Lee, S.; Johnson, J.; Vitzthum, C.; Kırlı, K.; Alver, B. H.; Park, P. J.

10.1101/440974 — bioinformatics — Posted on 2019-04-29

177 Incomplete annotation of disease-associated genes is limiting our understanding of Mendelian and complex neurogenetic disorders

Zhang, D.; Guelfi, S.; Ruiz, S. G.; Costa, B.; Reynolds, R. H.; D'Sa, K.; Liu, W.; Courtin, T.; Peterson, A.; Jaffe, A. E.; Hardy, J.; Botia, J.; Collado-Torres, L.; Ryten, M.

10.1101/499103 — bioinformatics — Posted on 2019-04-29

178 A direct glia-to-neuron natural transdifferentiation ensures nimble sensory-motor coordination of male mating behaviour

Molina-Garcia, L.; Kim, B.; Cook, S. J.; Bonnington, R.; O'Shea, J.; Sammut, M.; Gilbert, S. P. R.; Elliott, D.; Hall, D. H.; Emmons, S. W.; Barrios, A.; Poole, R. J.

10.1101/285320 — neuroscience — Posted on 2019-04-29

179 The NetrinG1/NGL-1 Axis promotes pancreatic tumorigenesis through cancer associated fibroblast driven nutritional support and immunosuppression

Francescone, R.; Barbosa Vendramini-Costa, D.; Franco-Barraza, J.; Wagner, J.; Muir, A.; Lau, A. N.; Gabitova, L.; Pazina, T.; Gupta, S.; Luong, T.; Shah, N.; Rollins, D.; Malik, R.; Thapa, R.; Restifo, D.; Zhou, Y.; Cai, K. Q.; Hensley, H. H.; Tan, Y.; Kruger, W. D.; Devarajan, K.; Balachandran, S.; Klein-Szanto, A. J.; El-Deiry, W. S.; Vander Heiden, M. G.; Peri, S.; Campbell, K. S.; Astsaturov, I.; Cukierman, E.

10.1101/330209 — cancer biology — Posted on 2019-04-29

180 Thermal cycling-hyperthermia in combination with polyphenols, epigallocatechin gallate and chlorogenic acid, exerts synergistic anticancer effect against human pancreatic cancer PANC-1 cells

Lu, C.-H.; Chen, W.-T.; Hsieh, C.-H.; Kuo, Y.-Y.; Chao, C.-Y.

10.1101/548552 — cancer biology — Posted on 2019-04-29

181 Biological Structure and Function Emerge from Scaling Unsupervised Learning to 250 Million Protein Sequences

Rives, A.; Goyal, S.; Meier, J.; Guo, D.; Ott, M.; Zitnick, C. L.; Ma, J.; Fergus, R.

10.1101/622803 — synthetic biology — Posted on 2019-04-29

182 Imaging of Morphological and Biochemical Hallmarks of Apoptosis with Optimized Optogenetic Actuators

Godwin, W. C.; Hoffmann, G. F.; Gray, T. J.; Hughes, R. M.

10.1101/551788 — biochemistry — Posted on 2019-04-29

183 Addiction beyond pharmacological effects: the role of environment complexity and bounded rationality

Ognibene, D.; Fiore, V. G.; Gu, X.

10.1101/179739 — neuroscience — Posted on 2019-04-29

184 Left-handedness is associated with greater fighting success in humans

Richardson, T.; Gilman, T.

10.1101/555912 — evolutionary biology — Posted on 2019-04-29

185 Vector competence for Zika virus unaffected by mosquito age but vectorial capacity of Ae. aegypti is multifactorial and age-dependent

Mayton, E. H.; Tramonte, A. R.; Christofferson, R. C.

10.1101/552125 — ecology — Posted on 2019-04-29

186 CHAP: a versatile tool for the structural and functional annotation of ion channel pores

Klesse, G.; Rao, S.; Sansom, M. S.; Tucker, S. J.

10.1101/527275 — biophysics — Posted on 2019-04-29

187 Brain-derived neurotrophic factor and TrkB levels in mice that lack vesicular zinc: Effects of age and sex

McAllister, B. B.; Bihelek, N.; Mychasiuk, R. M.; Dyck, R. H.

10.1101/421453 — neuroscience — Posted on 2019-04-29

188 Nuclear and mitochondrial genomic resources for the meltwater stonefly, Lednia tumana Ricker, 1952 (Plecoptera: Nemouridae)

Hotaling, S.; Kelley, J. L.; Weisrock, D. W.

10.1101/360180 — genomics — Posted on 2019-04-29

189 Genetic Architecture of Chilling Tolerance in Sorghum Dissected with a Nested Association Mapping Population

Marla, S. R.; Burow, G.; Chopra, R.; Hayes, C.; Olatoye, M.; Felderhoff, T.; Hu, Z.; Raymundo, R.; Perumal, R.; Morris, G. P.

10.1101/622894 — genetics — Posted on 2019-04-29

190 Previously reward-associated stimuli capture spatial attention in the absence of changes in the corresponding sensory representations as measured with MEG

Tankelevitch, L.; Spaak, E.; Rushworth, M. F.; Stokes, M. G.

10.1101/622589 — neuroscience — Posted on 2019-04-29

191 Circadian regulation of microRNA-target chimeras in Drosophila

Xia, X.; Fu, X.; Wu, B.; Zhu, J.; Zhao, Z.

10.1101/622183 — molecular biology — Posted on 2019-04-29

192 Tissue Mechanics Determines Cell Fate in the Axial Stem Zones

Wood, T. R.; Kyrsting, A. R.; Stegmaier, J.; Kucinski, I.; Kaminski, C. F.; Mikut, R.; Voiculescu, O.

10.1101/622571 — developmental biology — Posted on 2019-04-29

193 DNA barcode-guided lentiviral CRISPRa tool to trace and isolate individual clonal lineages in heterogeneous cancer cell populations

Akimov, Y.; Bulanova, D. R.; Abyzova, M.; Wennerberg, K.; Aittokallio, T.

10.1101/622506 — cancer biology — Posted on 2019-04-29

194 Myelination of major white matter tracts continues beyond childhood -- combining tractography and myelin water imaging

Meissner, T. W.; Genc, E.; Mädler, B.; Weigelt, S.

10.1101/622233 — neuroscience — Posted on 2019-04-29

195 Intron-targeted mutagenesis reveals roles for Dscam1 RNA pairing-mediated splicing bias in neuronal wiring

Hong, W.; Dong, H.; Zhang, J.; Zhou, F.; Wu, Y.; Shi, Y.; Chen, S.; Xu, B.; You, W.; Shi, F.; Yang, X.; Gong, Z.; Huang, J.; Jin, Y.

10.1101/622217 — molecular biology — Posted on 2019-04-29

196 A Molecular Link between Cell Wall Modification and Stringent Response in a Gram-positive Bacteria

Aggarwal, S. D.; Yerneni, S. S.; Narciso, A. R.; Filipe, S. R.; Hiller, N. L.

10.1101/622340 — microbiology — Posted on 2019-04-29

197 Epigenome-wide analysis uncovers a blood-based DNA methylation biomarker of lifetime cannabis use.

Markunas, C. A.; Hancock, D. B.; Xu, Z.; Quach, B.; Sandler, D. P.; Johnson, E. O.; Taylor, J. A.

10.1101/620641 — genomics — Posted on 2019-04-29

198 Efficacy of the MEK1/2 inhibitor trametinib in combination with clinically-investigated γ-secretase inhibitors in rhabdomyosarcoma

Cleary, M.; Hawkins, D. S.; Keller, C.

10.1101/622522 — cancer biology — Posted on 2019-04-29

199 Identifying Novel Candidates for Re-Purposing as Potential Therapeutic Agents for Alzheimer’s disease

Ballard, C.; Creese, B.; Gatt, A.; Doherty, P.; Francis, P.; Whitfield, D.; Corbett, A.; Corcoran, J.; Hanger, D.; Thuret, S.; Killick, R.; Williams, G.

10.1101/622308 — neuroscience — Posted on 2019-04-29

200 CRZ1 regulator and calcium cooperatively modulate holocellulases gene expression in Trichoderma reesei QM6a

Martins-Santana, L.; de Paula, R. G.; Gomes-Silva, A.; Lopes, D. C. B.; Silva, R. N.; Silva-Rocha, R.

10.1101/622647 — microbiology — Posted on 2019-04-29

201 Interactions of pharmaceutical companies with world countries, cancers and rare diseases from Wikipedia network analysis

Rollin, G.; Lages, J.; Serebriyskaya, T. S.; Shepelyansky, D. L.

10.1101/614016 — bioinformatics — Posted on 2019-04-29

202 The fungal sesquiterpenoid pyrenophoric acid B uses the plant ABA biosynthetic pathway to inhibit seed germination.

Lozano-Juste, J.; Masi, M.; Cimmino, A.; Clement, S.; Fernandez, M. A.; Antoni, R.; Meyer, S.; Rodriguez, P. L.; Evidente, A.

10.1101/622530 — plant biology — Posted on 2019-04-29

203 Dedicated setup for the photoconversion of fluorescent dye for functional electron microscopy.

Dobson, K. L.; Howe, C. L.; Nishimura, Y.; Marra, V.

10.1101/622639 — neuroscience — Posted on 2019-04-29

204 Proinflammatory and autoimmunogenic gut microbiome in systemic lupus erythematosus

Chen, B.; Jia, X.-m.; Xu, J.-y.; Zhao, L.-d.; Ji, J.-y.; Wu, B.-x.; Fei, Y.-y.; Yang, H.-x.; Chen, H.; Zuo, X.-x.; Li, H.; Pan, W.-y.; Wang, X.-h.; Ye, S.; Guo, D.-g.; Wang, L.; Li, J.; Peng, L.-y.; Zheng, W.-j.; Zhang, W.; Zhang, F.-c.; Zhang, J.-m.; He, W.; Cao, X.-t.; Liu, D.-p.; Wang, J.; Zhang, X.

10.1101/621995 — microbiology — Posted on 2019-04-29

205 Meta-analysis reveals that the provision of multiple ecosystem services requires a diversity of land covers

Gómez-Creutzberg, C.; Tylianakis, J. M.; Lagisz, M.; Nakagawa, S.; Brockerhoff, E. G.

10.1101/621706 — ecology — Posted on 2019-04-29

206 Formation of multinucleated variant endothelial cells with altered mitochondrial function in cultured coronary endothelium under simulated diabetes

Delgado De la Herran, H. C.; Donis Maturano, L.; Alvarez Delgado, C.; Villarreal, F.; Moreno Ulloa, A.

10.1101/622407 — cell biology — Posted on 2019-04-29

207 Structural basis for the transport mechanism of the human glutamine transporter SLC1A5 (ASCT2)

Yu, X.; Plotnikova, O.; Bonin, P. D.; Subashi, T. A.; McLellan, T. J.; Dumlao, D.; Che, Y.; Dong, Y.; Carpenter, E. P.; West, G. M.; Qiu, X.; Culp, J. S.; Han, S.

10.1101/622563 — biophysics — Posted on 2019-04-29

208 Reevaluation of the RNA binding properties of the Tetrahymena thermophila telomerase reverse transcriptase N-terminal domain

Palka, C.; Deshpande, A. P.; Stone, M. D.; Collins, K.

10.1101/621573 — biochemistry — Posted on 2019-04-29

209 How much do you perceive this? An analysis on perceptions of geometric features, personalities and emotions in virtual humans (Extended Version)

Araujo, V.; Migon Favaretto, R.; Knob, P.; Raupp Musse, S.; Vilanova, F.; Brandelli Costa, A.

10.1101/622167 — neuroscience — Posted on 2019-04-29

210 Neuronal avalanches in input and associative layers of auditory cortex

Bowen, Z.; Winkowski, D. E.; Seshadri, S.; Plenz, D.; Kanold, P. O.

10.1101/620781 — neuroscience — Posted on 2019-04-29

211 Light environment drives the shallow to mesophotic coral community transition

Tamir, R.; Eyal, G.; Kramer, N.; Laverick, J.; Loya, Y.

10.1101/622191 — ecology — Posted on 2019-04-29

212 Genetic screening identifies a SUMO protease dynamically maintaining centromeric chromatin and the associated centromere complex

Mitra, S.; Bodor, D. L.; David, A. F.; Mata, J. F.; Neumann, B.; Reither, S.; Tischer, C.; Jansen, L. E. T.

10.1101/620088 — cell biology — Posted on 2019-04-29

213 Quantitative Structural Assessment of Graded Receptor Agonism

Shang, J.; Brust, R.; Griffin, P.; Kamenecka, T.; Kojetin, D.

10.1101/617100 — biophysics — Posted on 2019-04-29

214 Structural destabilization and chaperone-assisted proteasomal degradation of MLH1 as a mechanism for Lynch syndrome

Abildgaard, A. B.; Stein, A.; Schultz-Knudsen, K.; Nielsen, S. V.; Papaleo, E.; Shrikhande, A.; Hoffmann, E. R.; Bernstein, I.; Gerdes, A.-M.; Takahashi, M.; Ishioka, C.; Lindorff-Larsen, K.; Hartmann-Petersen, R.

10.1101/622266 — biochemistry — Posted on 2019-04-29

215 Cortical ensemble activity discriminates auditory attentional states

Yao, P.-t.; Shen, J.; Chen, L.; Ge, S.; Xiong, Q.

10.1101/622332 — neuroscience — Posted on 2019-04-29

216 psupertime: supervised pseudotime inference for single cell RNA-seq data with sequential labels

Macnair, W.; Claassen, M.

10.1101/622001 — genomics — Posted on 2019-04-29

217 Chlamydia trachomatis outbreak: when the virulence-associated genome backbone imports a prevalence-associated major antigen signature

Borges, V.; Cordeiro, D.; Salas, A. I.; Lodhia, Z.; Correia, C.; Isidro, J.; Fernandes, C.; Rodrigues, A. M.; Azevedo, J.; Alves, J.; Roxo, J.; Rocha, M.; Corte-Real, R.; Vieira, L.; Borrego, M. J.; Gomes, J. P.

10.1101/622324 — genomics — Posted on 2019-04-29

218 Long-Term Exposure to Elevated Lipoprotein(a) Levels, Parental Lifespan and Risk of Mortality

Arsenault, B. J.; Pelletier, W.; Kaiser, Y.; Perrot, N.; Couture, C.; Khaw, K.-T.; Wareham, N.; Bosse, Y.; Pibarot, P.; Stroes, E. S. G.; Mathieu, P.; Theriault, S.; Boekholdt, S. M.

10.1101/615898 — genetics — Posted on 2019-04-29

219 1D MinION sequencing for large-scale species discovery: 7000 scuttle flies (Diptera: Phoridae) from one site in Kibale National Park (Uganda) revealed to belong to >650 species

Srivathsan, A.; Hartop, E.; Puniamoorthy, J.; Lee, W. T.; Kutty, S. N.; Kurina, O.; Meier, R.

10.1101/622365 — evolutionary biology — Posted on 2019-04-29

220 Decomposing variation in immune response in a wild rodent population

Wanelik, K. M.; Begon, M.; Arriero, E.; Bradley, J. E.; Friberg, I. M.; Jackson, J. A.; Taylor, C. H.; Paterson, S.

10.1101/622225 — ecology — Posted on 2019-04-29

221 Targeting RET Kinase in Neuroendocrine Prostate Cancer

VanDeusen, H.; Ramroop, J. R.; Morel, K. L.; Sheahan, A. V.; Sychev, Z.; Lau, N. A.; Cheng, L. C.; Tan, V.; Li, Z.; Petersen, A.; Lee, J. K.; Wook Park, J.; Yang, R.; Coleman, I.; Witte, O. N.; Morrissey, C.; Corey, E.; Nelson, P. S.; Ellis, L.; Drake, J. M.

10.1101/622415 — cancer biology — Posted on 2019-04-29

222 Deconvolute individual genomes from metagenome sequences through short read clustering

Li, K.; Wang, L.; Shi, L.; Deng, L.; Wang, Z.

10.1101/620666 — bioinformatics — Posted on 2019-04-29

223 The Escherichia coli Transcriptome Consists of Independently Regulated Modules

Sastry, A. V.; Gao, Y.; Szubin, R.; Hefner, Y.; Xu, S.; Kim, D.; Choudhary, K. S.; Yang, L.; King, Z. A.; Palsson, B. O.

10.1101/620799 — systems biology — Posted on 2019-04-29

224 Transcriptional profiling of Impatiens walleriana genes through different stages of downy mildew infection reveals novel genes involved in disease susceptibility

Suarez, S.; Naveed, Z. A.; Ali, G.

10.1101/622480 — plant biology — Posted on 2019-04-29

225 Multiple QTL mapping in autopolyploids: a random-effect model approach with application in a hexaploid sweetpotato full-sib population

da Silva Pereira, G.; Gemenet, D. C.; Mollinari, M.; Olukolu, B. A.; Wood, J. C.; Diaz, F.; Mosquera, V.; Gruneberg, W. J.; Khan, A.; Buell, C. R.; Yencho, G. C.; Zeng, Z.-B.

10.1101/622951 — genetics — Posted on 2019-04-29

226 Bacteriophage can promote the emergence of physiologically sub-optimal host phenotypes

Schenk, H.; Sieber, M.

10.1101/621524 — ecology — Posted on 2019-04-29

227 Irrational risk aversion in ants is driven by perceptual mechanisms

De Agro, M.; Grimwade, D.; Czaczkes, T. J.

10.1101/620054 — animal behavior and cognition — Posted on 2019-04-29

228 Powerful solution for experimental cerebral malaria treatment: artesunate and tetramethylpyrazine

Jiang, X.; Chen, L.; Zheng, Z.; Guo, Y.; Li, K.; Chen, Y.; Weng, X.; Yang, T.; Qu, S.; Liu, H.; Li, Y.; Zhu, X.

10.1101/622688 — pathology — Posted on 2019-04-29

229 CD71+ erythroid cells exacerbate HIV-1 infection by reactive oxygen species and trans-infect HIV to CD4+ T cells

Elahi, S.; Namdar, A.; Dunsmore, G.; Koleva, P.; Shahbaz, S.; Jovel, J.; Houston, S.

10.1101/622712 — immunology — Posted on 2019-04-29

230 Plant A20/AN1 proteins coordinate different immune responses including RNAi pathway for antiviral immunity

Chang, L.; Chang, H.-H.; Chiu, Y.-S.; Chang, J.-C.; Hsu, D.-W.; Tzean, Y.; Cheng, A.-P.; Lu, H.-C.; Yeh, H.-H.

10.1101/622696 — plant biology — Posted on 2019-04-29

231 Dear Editorial manager PLoS ONEA survey of vaccine-induced measles IgG antibody titer and the verification of changes in temporal differences of measles vaccination in young adults

Sasaki, H.; Fukunaga, T.; Asano, A.; Suzuki, Y.; Nakanishi, Y.; Kondo, J.; Ishikawa, H.; Shibata, N.

10.1101/622613 — microbiology — Posted on 2019-04-29

232 Morphogenesis and dynamics of slime molds in various environments

Patino-Ramirez, F.; Boussard, A.; Arson, C.; Dussutour, A.

10.1101/622662 — ecology — Posted on 2019-04-29

233 TAO Kinase 3 Overexpression Is a Poor Prognosis Marker for Lung Adenocarcinoma and Predicts Paclitaxel Resistance

Chang, P. M.-H.; Lai, T.-C.; Yang, Y.-C.; Chang, Y.-C.; Chiou, J.; Huang, M.-S.; Yang, C.-J.; Hsiao, M.

10.1101/622621 — cancer biology — Posted on 2019-04-29

234 An innovative non-invasive technique for subcutaneous tumour measurements

Delgado-SanMartin, J. A.; Beate, E.; Paczkowski, M.; Hackett, S.; Smith, A.; Waraich, W.; Klatzow, J.; Zabair, A.; Chabokdast, A.; Rubio Navarro, L.; Rahi, A.; Wilson, Z.

10.1101/622605 — cancer biology — Posted on 2019-04-29

235 Mechanically Resolved Imaging of Bacteria using Expansion Microscopy

Lim, Y.; Khariton, M.; Lane, K. M.; Shiver, A. L.; Ng, K. M.; Bray, S. R.; Qin, J.; Huang, K. C.; Wang, B.

10.1101/622654 — biophysics — Posted on 2019-04-29

236 Non-disclosure of tuberculosis diagnosis by patients to their household members in south western Uganda

Atwine, D.; Nyangoma, M.; Bajunirwe, F.

10.1101/622597 — epidemiology — Posted on 2019-04-29

237 Novel feeding and mating behaviors of a population of nautiluses, Nautilus belauensis, in Palau

Barord, G. J.; Swanson, R.; Ward, P.

10.1101/622456 — zoology — Posted on 2019-04-29

238 PURPOSEFUL DESIGN OF A SURVEY TOOL TO EVALUATE THE ADEQUACY OF HOSPITALS WATER SANITATION AND HYGIENE AND ALLOCATE RESPONSIBILITY FOR ACTION - FROM WASH FIT to WASH FAST

Maina, M.; Zosi, M.; Kimemia, G.; Mwaniki, P.; Hayter, A.; Montgomery, M.; McKnight, J.; Tosas-Auguet, O.; Schultsz, C.; English, M.

10.1101/622449 — epidemiology — Posted on 2019-04-29

239 The preparation of cyclopentadecanone and cyclopentadecanolide from Malania oleifera Chum oil

Liu, P.; Liu, X.; Lai, F.; Ma, L.; Li, W.; Huang, P.

10.1101/622423 — scientific communication and education — Posted on 2019-04-29

240 Phanerochaete chrysosporium strain B-22, a parasitic fungus infecting Meloidogyne incognita

Du, B.; Xu, Y.; Dong, H.; Yan, L.; wang, J.

10.1101/622472 — pathology — Posted on 2019-04-29

241 The Length Of Promoter Sequence Affects The De Novo Initiation By T7 RNA Polymerase In Vitro: New Insights Into The Evolution Of Promoters For Single Subunit RNA Polymerases.

Padmanabhan, R.; Miller, D.

10.1101/619395 — molecular biology — Posted on 2019-04-29

242 Exploring Deep Physiological Models for Nociceptive Pain Recognition

Thiam, P.; Bellmann, P.; Kestler, H. A.; Schwenker, F.

10.1101/622431 — bioinformatics — Posted on 2019-04-29

243 Dysmorphic neuron density is highest in the centre of epileptogenic cortical tubers

Stephenson, S. E. M.; Owens, H. G.; Richards, K. L.; Lee, W. S.; DArcy, C.; Barton, S.; Mandelstam, S. A.; Maixner, W. J.; MacGregor, D.; Petrou, S.; Lockhart, P. J.; Harvey, A. S.; Leventer, R. J.

10.1101/621607 — neuroscience — Posted on 2019-04-29

244 Stxbp1/Munc18-1 haploinsufficiency in mice recapitulates key features of STXBP1 encephalopathy and impairs cortical inhibition

Chen, W.; Cai, Z.-L.; Chao, E. S.; Chen, H.; Hao, S.; Chao, H.-T.; Kim, J. H.; Messier, J. E.; Zoghbi, H. Y.; Tang, J.; Swann, J. W.; Xue, M.

10.1101/621516 — neuroscience — Posted on 2019-04-29

245 Female mice are resilient to age-related decline of substantia nigra dopamine neuron firing parameters

Howell, R.; Dominguez-Lopez, S.; Parikh, I.; Chucair-Elliott, A. J.; Ocanas, S.; Freeman, W. M.; Beckstead, M. J.

10.1101/621680 — neuroscience — Posted on 2019-04-29

246 Evaluating the Impact of Purifying Selection on Species-level Molecular Dating

He, C.; Liang, D.; Zhang, P.

10.1101/622209 — evolutionary biology — Posted on 2019-04-29

247 Mosaic evolution, constraint, and constructional opportunity in great apes

Parins-Fukuchi, C.

10.1101/622134 — evolutionary biology — Posted on 2019-04-29

248 Temporal Effects on Radiation Responses in Nonhuman Primates: Identification of Biofluid Small Molecule Signatures by Gas Chromatography - Mass Spectrometry Metabolomics

Pannkuk, E.; Laiakis, E. C.; Girgis, M.; Dowd, S.; Dhungana, S.; Nishita, D.; Bujold, K.; Bakke, J.; Gahagen, J.; Authier, S.; Chang, P.; Fornace, A. J.

10.1101/620526 — biochemistry — Posted on 2019-04-29

249 UmuD and RecA* modulate the DNA-binding activity of DNA polymerase IV in Escherichia coli

Henrikus, S. S.; McGarth, A. E.; Jergic, S.; Ritger, M. L.; Pham, P. T.; Wood, E. A.; Goodman, M. F.; Cox, M. M.; van Oijen, A. M.; Ghodke, H.; Robinson, A.

10.1101/620195 — microbiology — Posted on 2019-04-29

250 The desmosomal cadherin Desmogon is necessary for the structural integrity of the Medaka notochord

Seleit, A.; Gross, K.; Wölk, M.; Autorino, C.; Centanin, L.

10.1101/620070 — developmental biology — Posted on 2019-04-29

251 Critical length in long read resequencing

De Coster, W.; Strazisar, M.; De Rijk, P.

10.1101/621862 — bioinformatics — Posted on 2019-04-29

252 Acoustically Detonated Biomolecules for Genetically Encodable Inertial Cavitation

Bar-Zion, A.; Nourmahnad, A.; Mittelstein, D.; Yoo, S.; Malounda, D.; Abedi, M.; Lee-Gosselin, A.; Maresca, D.; Shapiro, M. G.

10.1101/620567 — bioengineering — Posted on 2019-04-29

253 A new method of brain stimulation at ultra-high frequency

Jamali, Y.; Jamali, M.; Golshani, M.

10.1101/621771 — neuroscience — Posted on 2019-04-29

254 The guanine nucleotide exchange factor GBF1 participates in rotavirus replication

Martinez, J. L.; Arnoldi, F.; Schraner, E. M.; Eichwald, C.; Silva-Ayala, D.; Lee, E.; Sztul, E.; Burrone, O. R.; Lopez, S.; Arias, C. F.

10.1101/619924 — microbiology — Posted on 2019-04-29

255 Working Towards a Blood-Derived Gene Expression Biomarker Specific for Alzheimer’s Disease

Patel, H.; Iniesta, R.; Stahl, D.; Dobson, R. J. B.; Newhouse, S. J.

10.1101/621987 — genetics — Posted on 2019-04-29

256 The Pseudomonas aeruginosa accessory genome elements, including bacterial immune systems effect virulence towards C. elegans

Vasquez-Rifo, A. I.; Veksler-Lublinsky, I. I.; Cheng, Z.; Ausubel, F. M.; Ambros, V.

10.1101/621433 — evolutionary biology — Posted on 2019-04-29

257 When does gene flow facilitate evolutionary rescue?

Tomasini, M.; Peischl, S.

10.1101/622142 — evolutionary biology — Posted on 2019-04-29

258 When sinks become sources: adaptive colonization in asexuals

Lavigne, F.; Martin, G.; Anciaux, Y.; Papaix, J.; Roques, L.

10.1101/433235 — evolutionary biology — Posted on 2019-04-29

259 Evidence for rapid evolution in a grassland biodiversity experiment

van Moorsel, S. J.; Schmid, M. W.; Wagemaker, C. A. M.; van Gurp, T.; Schmid, B.; Vergeer, P.

10.1101/262303 — ecology — Posted on 2019-04-29

260 Marker subset selection and decision support range identification for acute myeloid leukemia classification model development with multiparameter flow cytometry

Choi, J.-S.; Nguyen, N. T.; Byun, H.-G.; Song, J.; Yoon, T. H.

10.1101/621797 — bioinformatics — Posted on 2019-04-29

261 Reproductive capacity of Varroa destructor in four different honey bee subspecies

Odemer, R.

10.1101/621946 — zoology — Posted on 2019-04-29

262 Estimating Attentional Set-Shifting Dynamics in Varying Contextual Bandits

Kour, G.; Morris, G.

10.1101/621300 — neuroscience — Posted on 2019-04-29

263 Distinct evolutionary trajectories of neuronal and hair cell nicotinic acetylcholine receptors

Marcovich, I.; Moglie, M. J.; Carpaneto Freixas, A. E.; Trigila, A.; Franchini, L. F.; Plazas, P. V.; Lipovsek, M.; Elgoyhen, A. B.

10.1101/621342 — neuroscience — Posted on 2019-04-29

264 Predation strategies of the bacterium Bdellovibrio bacteriovorus result in bottlenecks, overexploitation, minimal and optimal prey sizes

Summers, K.; Kreft, J.-U.

10.1101/621490 — microbiology — Posted on 2019-04-29

265 Preclinical immunoPET imaging of glioblastoma-infiltrating myeloid cells using Zirconium-89-labeled anti-CD11b antibody

Nigam, S.; McCarl, L. H.; Kumar, R.; Edinger, R. S.; Kurland, B. F.; Anderson, C. J.; Panigrahy, A.; Kohanbash, G.; Edwards, W. B.

10.1101/614511 — immunology — Posted on 2019-04-29

266 Long read sequencing reveals a novel class of structural aberrations in cancers: identification and characterization of cancerous local amplifications

Sakamoto, Y.; Xu, L.; Seki, M.; Yokoyama, T. T.; Kasahara, M.; Kashima, Y.; Ohashi, A.; Shimada, Y.; Motoi, N.; Tsuchihara, K.; Kobayashi, S.; Kohno, T.; Shiraishi, Y.; Suzuki, A.; Suzuki, Y.

10.1101/620047 — genomics — Posted on 2019-04-29

267 Transcriptomic analysis of probable asymptomatic and symptomatic Alzheimer brains

Patel, H.; Hodges, A. K.; Curtis, C.; Lee, S. h. H.; Troakes, C.; Dobson, R.; Newhouse, S. J.

10.1101/621912 — genetics — Posted on 2019-04-29

268 Variation in PU.1 binding and chromatin looping at neutrophil enhancers influences autoimmune disease susceptibility

Watt, S.; Vasquez, L.; Walter, K.; Mann, A. L.; Kundu, K.; Chen, L.; Yan, Y.; Ecker, S.; Burden, F.; Farrow, S.; Farr, B.; Iotchkova, V.; Elding, H.; Mead, D.; Tardaguila, M.; Ponstingl, H.; Richardson, D.; Datta, A.; Flicek, P.; Clarke, L.; Downes, K.; Pastinen, T.; Fraser, P.; Frontini, M.; Javierre, B. M.; Spivakov, M.; Soranzo, N.

10.1101/620260 — genetics — Posted on 2019-04-29

269 Population position along the fast-slow life-history continuum predicts intraspecific variation in actuarial senescence

Cayuela, H.; Lemaitre, J.-F.; Bonnaire, E.; Pichenot, J.; Schmidt, B.

10.1101/621425 — ecology — Posted on 2019-04-29

270 Inhibition of RNA Polymerase I Transcription Activates Targeted DNA Damage Response and Enhances the Efficacy of PARP Inhibitors in High-Grade Serous Ovarian Cancer

Sanij, E.; Hannan, K. M.; Yan, S.; Xuan, X.; Ahern, J. E.; Chan, K. T.; Son, J.; Kondrashova, O.; Lieschke, E.; Wakefield, M. J.; Trigos, A. S.; Frank, D.; Ellis, S.; Cullinane, C.; Kang, J.; Poortinga, G.; Nag, P.; Khanna, K. K.; Mileshkin, L.; McArthur, G. A.; Soong, J.; Berns, E. M. J. J.; Hannan, R. D.; Scott, C. L.; Shappard, K. E.; Pearson, R. B.

10.1101/621623 — cancer biology — Posted on 2019-04-29

271 Sex discordance and risk of breast cancer

Aduse-Poku, L.; Jahanfar, S.

10.1101/621417 — cancer biology — Posted on 2019-04-29

272 Single-Cell Signature Explorer for comprehensive visualization of single cell signatures across scRNA-seq data sets

PONT, F.; Tosolini, M.; Fournie, j.-j.

10.1101/621805 — bioinformatics — Posted on 2019-04-29

273 CoolBox: a interactive genomic data explorer for Jupyter Notebook

Xu, W.; Lin, D.; Hong, P.; Yi, L.; Tyagi, R.; Li, G.; Cao, G.

10.1101/614222 — bioinformatics — Posted on 2019-04-29

274 Identification of a dominant chlorosis phenotype through a forward screen of the Triticum turgidum cv. Kronos TILLING population

Harrington, S. A.; Cobo, N.; Karafiatova, M.; Dolezel, J.; Borrill, P.; Uauy, C.

10.1101/622076 — plant biology — Posted on 2019-04-29

275 Choice of Contact Points Modulates Sensorimotor Cortical Interactions for Dexterous Manipulation

Parikh, P. J.; Fine, J. M.; Santello, M.

10.1101/621466 — neuroscience — Posted on 2019-04-29

276 Automated quantification of small vessel disease brain changes on MRI predicts cognitive and functional decline

Jokinen, H.; Koikkalainen, J.; Laakso, H. M.; Melkas, S.; Nieminen, T.; Brander, A.; Korvenoja, A.; Rueckert, D.; Barkhof, F.; Scheltens, P.; Schmidt, R.; Fazekas, F.; Madureira, S.; Verdelho, A.; Wallin, A.; Wahlund, L.-O.; Waldemar, G.; Chabriat, H.; Hennerici, M.; O'Brien, J.; Inzitari, D.; Lotjonen, J.; Pantoni, L.; Erkinjuntti, T.

10.1101/621888 — neuroscience — Posted on 2019-04-29

277 Memory for Individual Items is Related to Non-Reinforced Preference Change

Botvinik-Nezer, R.; Bakkour, A.; Salomon, T.; Shohamy, D.; Schonberg, T.

10.1101/621292 — neuroscience — Posted on 2019-04-29

278 Transient Receptor Potential Ankyrin1 channel is endogenously expressed in T cells and regulates immune functions

Sahoo, S. S.; Majhi, R. K.; Tiwari, A.; Acharya, T.; Kumar, P. S.; Saha, S.; Goswami, C.; Chattopadhyay, S.

10.1101/621854 — immunology — Posted on 2019-04-29

279 Functional effects of variation in transcription factor binding highlight long-range gene regulation by epromoters

Mitchelmore, J.; Grinberg, N.; Wallace, C.; Spivakov, M.

10.1101/620062 — genomics — Posted on 2019-04-29

280 Investigating Coronary Artery Disease methylome through targeted bisulfite sequencing

Sengupta, S.; Ghose, S.; Ghosh, S.; Tanwar, V. S.; Tolani, P.; Sharma, A.; Bhardwaj, N.; KV, S.; Verma, A.; Jayarajan, R.; Sivasubbu, S.; Scaria, V.; Seth, S.

10.1101/621789 — genomics — Posted on 2019-04-29

281 De novo emergence of adaptive membrane proteins from thymine-rich intergenic sequences

Vakirlis, N.; Acar, O.; Hsu, B.; Castilho Coelho, N.; Van Oss, S. B.; Wacholder, A.; Medetgul-Ernar, K.; Ianotta, J.; McLysaght, A.; Camacho, C. J.; O'Donnell, A. F.; Ideker, T.; Carvunis, A.-R.

10.1101/621532 — evolutionary biology — Posted on 2019-04-29

282 Trait-specific trade-offs prevent niche expansion in two parasites

Lievens, E. J.; Michalakis, Y.; Lenormand, T.

10.1101/621581 — evolutionary biology — Posted on 2019-04-29

283 Mendelian randomisation analysis of the effect of educational attainment and cognitive ability on smoking behaviour

Sanderson, E.; Davey Smith, G.; Munafo, M.

10.1101/299826 — epidemiology — Posted on 2019-04-29

284 Artificial light is the main driver of nocturnal feeding by the Rock dove (Columba livia) in urban areas

Leveau, L.

10.1101/621508 — ecology — Posted on 2019-04-29

285 Bax mitochondrial residency is more critical than Bax oligomerization for apoptosis

Kuwana, T.; King, L.; Cosentino, K.; Suess, J.; Garcia-Saez, A. J.; Gilmore, A. P.; Newmeyer, D. D.

10.1101/618868 — cell biology — Posted on 2019-04-29

286 Stress fiber growth and remodeling determines cellular morphomechanics under uniaxial cyclic stretch

Chatterjee, A.; Kondaiah, P.; Gundiah, N.

10.1101/622092 — biophysics — Posted on 2019-04-29

287 Identification of Ca-rich dense granules in human platelets using scanning transmission X-ray microscopy

Tung, T. X.; Kwon, S. J.; Gerelkhuua, Z.; Choi, J.-S.; Song, J.; Yoon, T. H.

10.1101/622100 — biophysics — Posted on 2019-04-29

288 Theory of cyborg: a new approach to fish locomotion control

Jamali, M.; Jamali, Y.; Golshani, M.

10.1101/621839 — bioengineering — Posted on 2019-04-29

289 Overexpression of the Arabidopsis thaumatin-like protein 1 in transgenic potato plants enhances resistance against early and late blights

Ali, G.; Hu, X.; Reddy, A. S. N.

10.1101/621649 — plant biology — Posted on 2019-04-29

290 Redistribution of NORTIA in response to pollen tube arrival facilitates fertilization in Arabidopsis thaliana

Yuan, J.; Ju, Y.; Jones, D. S.; Zhang, W.; Lucca, N.; Staiger, C. J.; Kessler, S. A.

10.1101/621599 — plant biology — Posted on 2019-04-29

291 Tetrahydrocannabinolic Acid A (THCA-A) Reduces Adiposity And Prevents Metabolic Disease Caused By Diet-Induced Obesity

Palomares, B.; Ruiz-Pino, F.; Garrido-Rodriguez, M.; Prados, M. E.; Sanchez-Garrido, M. A.; Velasco, I.; Vazquez, M. J.; Nadal, X.; Ferreiro-Vera, C.; Morrugares, R.; Appendino, G.; Morello, G.; Calzado, M. A.; Tena-Sempere, M.; Munoz, E.

10.1101/622035 — pharmacology and toxicology — Posted on 2019-04-29

292 Hierarchical recurrent state space models reveal discrete and continuous dynamics of neural activity in C. elegans

Linderman, S. W.; Nichols, A. L. A.; Blei, D. M.; Zimmer, M.; Paninski, L.

10.1101/621540 — neuroscience — Posted on 2019-04-29

293 On the cortical mapping function -- visual space, cortical space, and crowding

Strasburger, H.

10.1101/621458 — neuroscience — Posted on 2019-04-29

294 Fungi form interkingdom microbial communities in the primordial human gut that develop with gestational age

Willis, K. A.; Purvis, J. H.; Myers, E. D.; Aziz, M. M.; Karabayir, I.; Klazer Gomes, C. K.; Peters, B. M.; Akbilgic, O.; Talati, A. J.; Pierre, J. F.

10.1101/621235 — microbiology — Posted on 2019-04-29

295 Evaluation of the Accelerate Pheno(TM)system to identify bacteria and determine antimicrobial susceptibility in positive blood cultures

Fernandez-Pittol, M.; Morales, J.; Rubio, E.; Fasanella, A.; Alejo-Sanchez, I.; Almela, M.; Marco, F.; Vila, J.; Casals-Pascual, C.

10.1101/621268 — microbiology — Posted on 2019-04-29

296 Germline-encoded TCR-MHC contacts promote TCR V gene bias in umbilical cord blood T cell repertoire

Tian, L.; Liu, X.; Qiu, X.; Gao, K.; Chen, L.; Zhang, Y.; Zhao, Y.; Wan, Z.; Wu, J.; Lin, L.; Kuang, Y.; Lu, J.; Zhang, X.

10.1101/621821 — immunology — Posted on 2019-04-29

297 Effect of geographic isolation on the nasal virome of indigenous children

Altan, E.; Dib, J. C.; Gulloso, A. R.; Escribano Juandigua, D.; Deng, X.; Bruhn, R.; Hildebrand, K.; Freiden, P.; Yamamoto, J.; Shultz-Cherry, S.; Delwart, E.

10.1101/616342 — epidemiology — Posted on 2019-04-29

298 Sex makes them sleepy: host reproductive status induces diapause in a parasitoid population experiencing harsh winters

Tougeron, K.; Brodeur, J.; van Baaren, J.; Renault, D.; Le Lann, C.

10.1101/371385 — ecology — Posted on 2019-04-29

299 TimeTeller: a New Tool for Precision Circadian Medicine and Cancer Prognosis

Vlachou, D.; Bjarnason, G. A.; Giacchetti, S.; Levi, F.; Rand, D. A.

10.1101/622050 — cancer biology — Posted on 2019-04-29

300 Synthetic lethality targeting LKB1 mutant and EGFR wild type human non-small cell lung cancer cells by glucose starvation and SGLT2 inhibition

Ren, Y.; Chen, J.; Mo, X.; Yang, Q.; Chen, P.; Lu, G.; Tan, H. W.-S.; Yi, J.; Yu, Q.; Kim, Y.-S.; Mallilankaraman, K.; Shen, H.-M.

10.1101/622126 — cancer biology — Posted on 2019-04-29

301 Visualizing movements in E. coli F1Fo ATP synthase indicates how the F1 and Fo motors are coupled

Sobti, M.; Walshe, J. L.; Ishmukhametov, R.; Stewart, A. G.

10.1101/622084 — biophysics — Posted on 2019-04-29

302 FIREcaller: an R package for detecting frequently interacting regions from Hi-C data

Crowley, C.; Yang, Y.; Qiu, Y.; Hu, B.; Won, H.; Ren, B.; Hu, M.; Li, Y.

10.1101/619288 — bioinformatics — Posted on 2019-04-29

303 Probability-based detection of phosphoproteomic uncertainty reveals rare signaling events driven by oncogenic kinase gene fusion

Robin, X.; Voellmy, F.; Ferkinghoff-Borg, J.; Howard, C.; Altenburg, T.; Engel, M.; Simpson, C.; Saginc, G.; Koplev, S.; Klipp, E.; Longden, J.; Linding, R.

10.1101/621961 — systems biology — Posted on 2019-04-29

304 Systematic determination of in vitro phenotypic resistance to HIV-1 integrase strand transfer inhibitors from clinical samples

Shahid, A.; Zhang, W. W.; Montoya, V.; Cheung, P. K.; Oliveira, N.; Sidhu, M. S.; Woods, C. K.; Robbins, M. A.; Brumme, C. J.; Harrigan, P. R.

10.1101/621755 — molecular biology — Posted on 2019-04-29

305 Super resolution imaging of a distinct chromatin loop in human lymphoblastoid cells

Ruan, Y.; Plewczynski, D.; Zhu, J. J.; Parteka, Z.; Lee, B.; Szalaj, P.; Wang, P.; Jodkowska, K.; Arron, J.; Chew, T. L.

10.1101/621920 — molecular biology — Posted on 2019-04-29

306 Incursion of killer sponge Terpios hoshinota on the coral reefs of Lakshadweep archipelago

Das, R. R.; CR, S.; Mohan, G.; KR, A.; Samuel, D.; Ramachandran, P.; Ramachandran, R.

10.1101/617662 — ecology — Posted on 2019-04-29

307 Snail induces epithelial cell extrusion through transcriptional control of RhoA contractile signalling and cell matrix adhesion

Wee, K.; Zadeh, S.; Verma, S.; Daly, R. J.; Yap, A. S.; Davis, M. J.; Budnar, S.

10.1101/621698 — cell biology — Posted on 2019-04-29

308 Frequency of mutations in 21 hereditary breast and ovarian cancer susceptibility genes among high-risk Chinese individuals

Shao, D.; Cheng, S.; Guo, F.; Yuan, Y.; Hu, K.; Wang, Z.; Meng, X.; Jin, X.; Xiong, Y.; Chai, X.; Li, H.; Zhang, Y.; Zhang, H.; Liu, J.; Ye, M.

10.1101/514539 — cancer biology — Posted on 2019-04-29

309 Different subtypes of influenza A viruses target different human proteins and pathways leading to different pathogenic phenotypes

Wang, Y.; Song, T.; Li, K.; Jin, Y.; Yue, J.; Ren, H.; Liang, L.

10.1101/541177 — microbiology — Posted on 2019-04-29

310 Nanotopography reveals metabolites that maintain the immunosuppressive phenotype of mesenchymal stem cells

Ross, E.; Turner, L.-A.; Saeed, A.; Burgess, K.; Blackburn, G.; Reynolds, P.; Wells, J.; Mountford, J.; Gadegaard, N.; Salmeron-Sanchez, M.; Oreffo, R.; Dalby, M.

10.1101/603332 — bioengineering — Posted on 2019-04-29

311 Hairless as a novel component of the Notch signaling pathway

Miller, S. W.; Movsesyan, A.; Zhang, S.; Fernandez, R.; Posakony, J. W.

10.1101/621367 — evolutionary biology — Posted on 2019-04-29

312 UK phenomics platform for developing and validating EHR phenotypes: CALIBER

Denaxas, S.; Gonzalez-Izquierdo, A.; Direk, K.; Fitzpatrick, N.; Fatemifar, G.; Banerjee, A.; Dobson, R.; Howe, L. J.; Kuan, V.; Lumbers, T.; Pasea, L.; Patel, R.; Shah, A. D.; Hingorani, A.; Sudlow, C.; Hemingway, H.

10.1101/539403 — epidemiology — Posted on 2019-04-29

313 Liquid-Liquid Phase Separation is Driven by Large-Scale Conformational Unwinding and Fluctuations of Intrinsically Disordered Protein Molecules

Majumdar, A.; Dogra, P.; Maity, S.; Mukhopadhyay, S.

10.1101/621714 — biophysics — Posted on 2019-04-29

314 The Semantics of Adjective Noun Phrases in the Human Brain

Fyshe, A.; Sudre, G.; Wehbe, L.; Rafidi, N.; Mitchell, T. M.

10.1101/089615 — neuroscience — Posted on 2019-04-28

315 Huntingtin confers fitness but is not embryonically essential in zebrafish development

Sidik, H.; Ang, C. J.; Pouladi, M. A.

10.1101/615591 — developmental biology — Posted on 2019-04-28

316 Point mutations in topoisomerase I alter the mutation spectrum in E. coli and impact the emergence of drug resistance genotypes

Bachar, A.; Itzhaki, E.; Gleizer, S.; Shamshoom, M.; Milo, R.; Antonovsky, N.

10.1101/621045 — microbiology — Posted on 2019-04-28

317 Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia

Wingo, T.; Yang, J.; Fan, W.; Logsdon, B.; Canon, S. M.; Yao, B.; Seyfried, N.; Lah, J.; Levey, A.; Boyle, P.; Schneider, J.; De Jager, P.; Bennett, D.; Wingo, A.

10.1101/620815 — genomics — Posted on 2019-04-28

318 Adaptive substitutions underlying cardiac glycoside insensitivity in insects exhibit epistasis in vivo.

Taverner, A. M.; Yang, L.; Barile, Z. J.; Becky, L.; Peng, J.; Pinharanda, A.; Rao, A.; Roland, B. P.; Talsma, A. D.; Wei, D.; Petschenka, G.; Palladino, M. J.; Andolfatto, P.

10.1101/621185 — evolutionary biology — Posted on 2019-04-28

319 Common and unique effects of HD-tDCS to the social brain across cultural groups

Martin, A. K.; Su, P.; Meinzer, M.

10.1101/408799 — neuroscience — Posted on 2019-04-28

320 Oral prescription opioid-seeking behavior in male and female mice

Phillips, A. G.; McGovern, D. J.; Lee, S.; Ro, K.; Huynh, D. T.; Elvig, S. K.; Fegan, K. N.; Root, D. H.

10.1101/621177 — neuroscience — Posted on 2019-04-28

321 Time elapsed between Zika and Dengue infections improves the immune response against Dengue without viremia enhancement in rhesus macaques

Perez-Guzman, E. X.; Pantoja, P.; Serrano-Collazo, C.; Hassert, M. A.; Ortiz-Rosa, A.; Rodriguez, I. V.; Giavedoni, L.; Hodara, V.; Parodi, L.; Cruz, L.; Arana, T.; White, L. J.; Martinez, M. I.; Weiskopf, D.; Brien, J. D.; de Silva, A.; Pinto, A. K.; Sariol, C. A.

10.1101/621094 — microbiology — Posted on 2019-04-28

322 Distribution and density of oxpeckers on giraffes in Hwange National Park, Zimbabwe

Gagnon, R.; Mabika, C. T.; Bonenfant, C.

10.1101/621151 — ecology — Posted on 2019-04-28

323 TeraVR Empowers Precise Reconstruction of Complete 3-D Neuronal Morphology in the Whole Brain

Wang, Y.; Li, Q.; Liu, L.; Zhou, Z.; Wang, Y.; Kong, L.; Zhong, N.; Chai, R.; Luo, X.; Guo, Y.; Hawrylycz, M.; Luo, Q.; Gu, Z.; Xie, W.; Zeng, H.; Peng, H.

10.1101/621011 — neuroscience — Posted on 2019-04-28

324 Sociality and Interaction Envelope Organize Visual Action Representations

Tarhan, L.; Konkle, T.

10.1101/618272 — neuroscience — Posted on 2019-04-28

325 Behaviors and Energy Source of Mycoplasma gallisepticum Gliding

Mizutani, M.; Miyata, M.

10.1101/620922 — microbiology — Posted on 2019-04-28

326 Microbial Similarity between Students in a Common Dormitory Environment Reveals the Forensic Potential of Individual Microbial Signatures

Richardson, M.; Gottel, N.; Gilbert, J. A.; Lax, S.

10.1101/620948 — ecology — Posted on 2019-04-28

327 Leptin and adiponectin correlations with body composition and lipid profile in children with Autism Spectrum Disorder

Grokoski, K. C.; Faccioli, L. S.; Perry, I. S.; Riesgo, R.

10.1101/621003 — neuroscience — Posted on 2019-04-28

328 Evolution of conspicuousness in defended species involved in Mullerian mimicry

Sculfort, O.; Aubier, T. G.; Maisonneuve, L.; Elias, M.; Llaurens, V.

10.1101/620963 — evolutionary biology — Posted on 2019-04-28

329 RNAsamba: coding potential assessment using ORF and whole transcript sequence information

Camargo, A. P.; Sourkov, V.; Carazzolle, M. F.

10.1101/620880 — bioinformatics — Posted on 2019-04-28

330 Immunological efficacy of self-assembled nanoparticle anti-mite vaccine

Smith, J.; Kowalski, S.

10.1101/620823 — bioengineering — Posted on 2019-04-28

331 THE FIRST REPORT ON CRYPTOCOCCUS PROFILES OF ISOLATES FROM PATIENTS ATTENDING DR GEORGE MUKHARI ACADEMIC HOSPITAL, SOUTH AFRICA

Jiyane, E. Z.; Nemarude, L.; Nchabeleng, M.

10.1101/620930 — microbiology — Posted on 2019-04-28

332 De novo mutations in fetal brain specific enhancers play a significant role in severe intellectual disability

De Vas, M. G.; Garstang, M. G.; Joshi, S. S.; Khan, T.; Atla, G.; Parry, D.; Moore, D.; Cebola, I.; Zhang, S.; Cui, W.; Lampe, A. K.; Lam, W. W.; FitzPatrick, D. R.; Madapura, P. M.; Atanur, S. S.

10.1101/621029 — genomics — Posted on 2019-04-28

333 Skeletal descriptions of shape provide unique perceptual information for object recognition

Ayzenberg, V.; Lourenco, S. F.

10.1101/518795 — neuroscience — Posted on 2019-04-28

334 Distinct changes in morphometric networks in aging versus Alzheimer’s disease dementia

Pichet Binette, A.; Gonneaud, J.; Vogel, J. W.; La Joie, R.; Rosa-Neto, P.; Collins, L.; Poirier, J.; Breitner, J. C. S.; Villeneuve, S.; Vachon-Presseau, E.; Alzheimer's Disease Neuroimaging Initiative, ; PREVENT-AD Research Group,

10.1101/615401 — neuroscience — Posted on 2019-04-28

335 Causes and biophysical consequences of cellulose production by Pseudomonas fluorescens SBW25 at the air-liquid interface

Ardre, M.; Dufour, D.; Rainey, P. B.

10.1101/538561 — microbiology — Posted on 2019-04-28

336 A convolutional neural network for predicting transcriptional regulators of genes in Arabidopsis transcriptome data reveals classification based on positive regulatory interactions

MacLean, D.

10.1101/618926 — bioinformatics — Posted on 2019-04-28

337 Crystal structures of the outer membrane transporter FoxA provide novel insights into TonB-mediated siderophore uptake and signalling

Josts, I.; Veith, K.; Tidow, H.

10.1101/621219 — molecular biology — Posted on 2019-04-28

338 Tousled-like kinase activity is required for transcriptional silencing and suppression of innate immune signaling

Segura-Bayona, S.; Villamor-Paya, M.; Attolini, C. S.-O.; Stracker, T. H.

10.1101/621409 — molecular biology — Posted on 2019-04-28

339 The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation

Batki, J.; Schnabl, J.; Wang, J.; Handler, D.; Andreev, V.; Stieger, C.; Novatchkova, M.; Lampersberger, L.; Kauneckaite, K.; Xie, W.; Mechtler, K.; Patel, D.; Brennecke, J.

10.1101/609693 — molecular biology — Posted on 2019-04-28

340 Taxonomic propagation of phenotypic features predict host pathogen interactions

Liu-Wei, W.; Kafkas, S.; Hoehndorf, R.

10.1101/508762 — bioinformatics — Posted on 2019-04-28

341 Experimental colitis drives enteric alpha-synuclein accumulation and Parkinson-like brain pathology

Grathwhohl, S.; Quansah, E.; Maroof, N.; Steiner, J. A.; Spycher, L.; Benmansour, F.; Duran-Pacheco, G.; Siebourg-Polster, J.; Oroszlan-Szovik, K.; Remy, H.; Haenggi, M.; Stawiski, M.; Sehlhausen, M.; Maliver, P.; Wolfert, A.; Emrich, T.; Madaj, Z.; Escobar Galvis, M. L.; Mueller, C.; Herrmann, A.; Brundin, P.; Britschgi, M.

10.1101/505164 — neuroscience — Posted on 2019-04-28

342 Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction

Wang, J. D.; Anderson, B. W.; Liu, K.; Wolak, C.; Dubiel, K.; Satyshur, K. A.; Keck, J.

10.1101/621474 — biochemistry — Posted on 2019-04-28

343 Dual delivery of nucleic acids and PEGylated-bisphosphonates via calcium phosphate nanoparticles

Bisso, S.; Mura, S.; Castagner, B.; Couvreur, P.; Leroux, J.-C.

10.1101/621102 — pharmacology and toxicology — Posted on 2019-04-28

344 Integrated K+ channel and K+-Cl- cotransporter functions regulate fin proportionality in zebrafish

Lanni, J. S.; Peal, D.; Ekstrom, L.; Chen, H.; Stanclift, C.; Bowen, M.; Mercado, A.; Gamba, G.; Kahle, K.; Harris, M.

10.1101/621243 — genetics — Posted on 2019-04-28

345 Myosin XI Interacting with a RabE GTPase Is Required for Polarized Growth

Orr, R. G.; Furt, F.; Warner, E. L.; Agar, E. M.; Garbarino, J. M.; Cabral, S. E.; Dubuke, M. L.; Butt, A. M.; Munson, M.; Vidali, L.

10.1101/617167 — cell biology — Posted on 2019-04-28

346 Genetic Monitoring and Molecular Phylogeny for Cymothoid Isopod Invasion in Egyptian Lake Qarun Fishes by Using adopted taxonomic marker (COI)

Hassan, M. A.

10.1101/614578 — genetics — Posted on 2019-04-28

347 Love and friendship at first sight: Rapid neural representations of personal relevance

Bayer, M.; Berhe, O.; Dziobek, I.; Johnstone, T.

10.1101/585133 — neuroscience — Posted on 2019-04-28

348 Modularity, criticality and evolvability of a developmental gene regulatory network

Verd, B.; Monk, N. A.; Jaeger, J.

10.1101/413211 — developmental biology — Posted on 2019-04-28

349 The Contribution of Parietal Cortex to Visual Salience

Chen, X.; Zirnsak, M.; Vega, G. M.; Govil, E.; Lomber, S.; Moore, T.

10.1101/619643 — neuroscience — Posted on 2019-04-28

350 Carry-over effects of temperature and pCO2 in multiple Olympia oyster populations

Spencer, L. H.; Venkataraman, Y. R.; Crim, R.; Ryan, S.; Horwith, M. J.; Roberts, S. B.

10.1101/616375 — physiology — Posted on 2019-04-27

351 Id proteins promote a cancer stem cell phenotype in triple negative breast cancer via Robo1-dependent c-Myc activation

Teo, W. S.; Holliday, H.; Karthikeyan, N.; Cazet, A. S.; Roden, D. L.; Harvey, K.; Konrad, C. V.; Murali, R.; Varghese, B. A.; T., A. P.; Chan, C.-L.; McFarland, A.; Junankar, S.; Ye, S.; Yang, J.; Nikolic, I.; Shah, J. S.; Baker, L. A.; Millar, E. K. A.; Naylor, M. J.; Ormandy, C. J.; Lakhani, S. R.; Kaplan, W.; Mellick, A. S.; O'Toole, S. A.; Nair, R.; Swarbrick, A.

10.1101/497313 — cancer biology — Posted on 2019-04-27

352 Designing a novel multi-epitope T vaccine for \"targeting protein for Xklp-2\" (TPX2) in hepatocellular carcinoma based on immunoinformatics approach

Ghahremanifard, P.; Afzali, F.; Rostami, A.; Nayeri, Z.; Bambai, B.; Minuchehr, Z.

10.1101/570952 — bioinformatics — Posted on 2019-04-27

353 Genome-wide analyses indirectly implicate miRNA regulatory mechanisms in Obsessive-compulsive Disorder psychopathology

McGregor, N. W.; O'Connell, K. S.; TS/ OCD PGC Workgroup, ; Davis, L.; Mathews, C.; Lochner, C.; Stein, D.

10.1101/601401 — neuroscience — Posted on 2019-04-27

354 Estimating genetic and non-genetic effects for host susceptibility, infectivity and recoverability using temporal epidemic data

Pooley, C. M.; Bishop, S. C.; Doeschl-Wilson, A. B.; Marion, G.

10.1101/618363 — epidemiology — Posted on 2019-04-27

355 An Analytical Theory of Balanced Cellular Growth

Dourado, H.; Lercher, M. J.

10.1101/607374 — biophysics — Posted on 2019-04-27

356 Boundary effects of expectation in human pain perception

Hird, E. J.; Charalambous, C.; El-Deredy, W.; Jones, A. K.; Talmi, D.

10.1101/467738 — neuroscience — Posted on 2019-04-27

357 Collective excitations in alpha-helical protein structures interacting with the environment

Kadantsev, V. N.; Goltsov, A.

10.1101/457580 — biophysics — Posted on 2019-04-27

358 Drop-In Biofuel production by using fatty acid photodecarboxylase from Chlorella variabilis in the oleaginous yeast Yarrowia lipolytica.

Bruder, S.; Moldenhauer, E.; Ledesma-Amaro, R.; Kabisch, J.

10.1101/468876 — bioengineering — Posted on 2019-04-27

359 Sperm gatekeeping: 3D imaging reveals a constricted entrance to zebra finch sperm storage tubules

Mendonca, T.; Cadby, A. J.; Hemmings, N.

10.1101/451484 — evolutionary biology — Posted on 2019-04-27

360 A new approach to automated CBMN scoring following high doses

Repin, M.; Brenner, D. J.; Garty, G.

10.1101/620971 — cell biology — Posted on 2019-04-27

361 Tuning intercellular cohesion with membrane-anchored oligonucleotides

Hoffecker, I. T.; Arima, Y.; Iwata, H.

10.1101/620989 — biophysics — Posted on 2019-04-27

362 Structural basis for the differential regulatory roles of the PDZ domain in C-terminal processing proteases

Chueh, C.-K.; Som, N.; Ke, L.-C.; Ho, M.-R.; Reddy, M.; Chang, C.-I.

10.1101/621037 — biophysics — Posted on 2019-04-27

363 Signaling via GABAB receptors regulates early development and neurogenesis in the basal metazoan Nematostella vectensis

Levy, S.; Brekhman, V.; Bakhman, A.; Sebe-Pedros, A.; Kosloff, M.; Lotan, T.

10.1101/621060 — molecular biology — Posted on 2019-04-27

364 Tendon response to matrix unloading is determined by the patho-physiological niche

Wunderli, S. L.; Blache, U.; Beretta Piccoli, A.; Niederoest, B.; Holenstein, C. N.; Passini, F.; Silvan, U.; Bundgaard, L.; auf dem Keller, U.; Snedeker, J. G.

10.1101/620534 — molecular biology — Posted on 2019-04-27

365 Finding high-quality metal ion-centric regions across the worldwide Protein Data Bank

Yao, S.; Moseley, H. N. B.

10.1101/619809 — molecular biology — Posted on 2019-04-27

366 Functional relevance of dual olfactory bulb in olfactory coding

Kuruppath, P.; Bai, L.; Belluscio, L.

10.1101/588996 — neuroscience — Posted on 2019-04-27

367 Effect of mannose modified chitosan on uptake of nanoparticles by macrophages

Smith, J.; Lowsberg, D.

10.1101/620906 — bioengineering — Posted on 2019-04-27

368 Skeletal descriptions of shape provide unique perceptual information for object recognition

Ayzenberg, V.; Lourenco, S. F.

10.1101/518795 — neuroscience — Posted on 2019-04-27

369 The genomic diversification of clonally propagated grapevines

Vondras, A.; Minio, A.; Blanco-Ulate, B.; Figueroa, R.; Penn, M.; Zhou, Y.; Seymour, D.; Zhou, Y.; Liang, D.; Espinoza, L.; Anderson, M.; Walker, M. A.; Gaut, B.; Cantu, D.

10.1101/585869 — genomics — Posted on 2019-04-27

370 ExpansionHunter: A sequence-graph based tool to analyze variation in short tandem repeat regions

Dolzhenko, E.; Deshpande, V.; Schlesinger, F.; Krusche, P.; Petrovski, R.; Chen, S.; Emig-Agius, D.; Gross, A.; Narzisi, G.; Bowman, B.; Scheffler, K.; van Vugt, J. J. F. A.; French, C.; Sanchis-Juan, A.; Ibanez, K.; Tucci, A.; Lajoie, B.; Veldink, J. H.; Raymond, L.; Taft, R. J.; Bentley, D. R.; Eberle, M. A.

10.1101/572545 — bioinformatics — Posted on 2019-04-27

371 Machine learning predicts early-onset acute organ failure in critically ill patients with sickle cell disease

Mohammed, A.; Podila, P. S.; Davis, R. L.; Ataga, K. I.; Hankins, J. S.; Kamaleswaran, R.

10.1101/614941 — bioinformatics — Posted on 2019-04-27

372 A knowledge-based scoring function to assess the stability of quaternary protein assemblies

Dhawanjewar, A. S.; Roy, A. A.; Madhusudhan, M. S.

10.1101/562520 — bioinformatics — Posted on 2019-04-27

373 A consensus molecular classification of muscle-invasive bladder cancer

Kamoun, A.; de Reynies, A.; Allory, Y.; Sjodahl, G.; Robertson, A. G.; Seiler, R.; Hoadley, K.; Al-Ahmadie, H.; Choi, W.; Groeneveld, C. S.; Castro, M. A. A.; Fontugne, J.; Eriksson, P.; Mo, Q.; Kardos, J.; Zlotta, A.; Hartmann, A.; Dinney, C. P.; Bellmunt, J.; Powles, T.; Malats, N.; Chan, K. S.; Kim, W. Y.; McConkey, D. J.; Black, P. C.; Dyrskjot, L.; Hoglund, M.; Lerner, S. P.; Real, F. X.; Radvanyi, F.; The Bladder Cancer Molecular Taxonomy Group,

10.1101/488460 — cancer biology — Posted on 2019-04-27

374 All-Assay-Max2 pQSAR: Activity predictions as accurate as 4-concentration IC50s for 8,558 Novartis assays

Martin, E. J.; Polyakov, V. R.; Zhu, X.-W.; Mukherjee, P.; Tian, L.; Liu, X.

10.1101/620864 — bioinformatics — Posted on 2019-04-27

375 PSC-RED, an Albumin-Free Robust Erythroid Differentiation Method to Produce Enucleated Red Blood Cells from Human Pluripotent Stem Cells

Olivier, E. E.; Zhang, S.; Yan, Z.; Suzuka, S.; Roberts, K. E.; Wang, K. E.; Bouhassira, E. E.

10.1101/616748 — bioengineering — Posted on 2019-04-27

376 Preparation and pharmacokinetics of genistein MePEG-PLGA copolymer micelles

Smith, J.; Swartz, M.

10.1101/620898 — bioengineering — Posted on 2019-04-27

377 Plant uses in a traditional fisherman community in northeastern Brazil

Tng, D. Y.; Apgaua, D. M.; Lisboa, M. D.; El-Hani, C. N.

10.1101/620542 — plant biology — Posted on 2019-04-27

378 Immune Landscape of Invasive Ductal Carcinoma Tumour Microenvironment Identifies a Prognostic and Immunotherapeutically Relevant Gene Signature

Bao, X.; Shi, R.; Zhang, K.; Xin, S.; Li, X.; Zhao, Y.; Wang, Y.

10.1101/620849 — cancer biology — Posted on 2019-04-27

379 singleCellHaystack: Finding surprising genes in single cell transcriptome data

Vandenbon, A.; Diez, D.

10.1101/557967 — bioinformatics — Posted on 2019-04-27

380 Easy Two-Photon Image Scanning Microscopy with SPAD Array and Blind Image Reconstruction

Koho, S. V.; Slenders, E.; Tortarolo, G.; Castello, M.; Buttafava, M.; Villa, F.; Tcarenkova, E.; Ameloot, M.; Bianchini, P.; Sheppard, C. J. R.; Diaspro, A.; Tosi, A.; Vicidomini, G.

10.1101/563288 — bioengineering — Posted on 2019-04-27

381 Fast and robust animal pose estimation

Graving, J. M.; Chae, D.; Naik, H.; Li, L.; Koger, B.; Costelloe, B. R.; Couzin, I. D.

10.1101/620245 — animal behavior and cognition — Posted on 2019-04-27

382 Error processing in the adolescent brain: Age-related differences in electrophysiology, behavioral adaptation, and brain morphology

Overbye, K.; Walhovd, K. B.; Paus, T.; Fjell, A. M.; Huster, R. J.; Tamnes, C. K.

10.1101/487959 — neuroscience — Posted on 2019-04-27

383 Postural adjustments in anticipation of predictable perturbations allow elderly fallers to achieve a balance recovery performance equivalent to elderly non-fallers

Le Mouel, C.; Tisserand, R.; Robert, T.; Brette, R.

10.1101/506501 — neuroscience — Posted on 2019-04-27

384 Neogenin-1 distinguishes between myeloid-biased and balanced Hoxb5+ long-term hematopoietic stem cells

Gulati, G. S.; Zukowska, M.; Noh, J.; Zhang, A.; Sinha, R.; George, B.; Wesche, D.; Weissman, I. L.; Szade, K.

10.1101/608398 — cell biology — Posted on 2019-04-27

385 The biochemical activities of the Saccharomyces cerevisiae Pif1 helicase are regulated by its N-terminal domain

Nickens, D. G.; Sausen, C. W.; Bochman, M.

10.1101/596098 — biochemistry — Posted on 2019-04-27

386 Robustness and timing of cellular differentiation through population-based symmetry breaking

Stanoev, A.; Schroeter, C.; Koseska, A.

10.1101/578898 — systems biology — Posted on 2019-04-27

387 ezTrack: An open-source video analysis pipeline for the investigation of animal behavior

Pennington, Z. T.; Dong, Z.; Bowler, R.; Feng, Y.; Vetere, L. M.; Shuman, T.; Cai, D. J.

10.1101/592592 — neuroscience — Posted on 2019-04-27

388 Discovery of novel thrips vector proteins that bind to the viral attachment protein of the plant bunyavirus, tomato spotted wilt virus

Badillo-Vargas, I. E.; Chen, Y.; Martin, K. M.; Rotenberg, D.; Whitfield, A. E.

10.1101/416560 — microbiology — Posted on 2019-04-27

389 Phylogenetic synecdoche demonstrates optimality of subsampling and improves recovery of the Blaberoidea phylogeny

Evangelista, D. A.; Simon, S.; Wilson, M. M.; Kohli, M. K.; Ware, J. L.; Kawahara, A. Y.; Wipfler, B.; Bethoux, O.; Grandcolas, P.; Legendre, F.

10.1101/601237 — evolutionary biology — Posted on 2019-04-27

390 Ultra-rare variants drive substantial cis-heritability of human gene expression

Hernandez, R. D.; Uricchio, L. H.; Hartman, K.; Ye, J.; Dahl, A.; Zaitlen, N.

10.1101/219238 — evolutionary biology — Posted on 2019-04-27

391 Environmental drivers define contrasting microbial habitats, diversity and functional redundancy in Lake Baikal, Siberia

Wilburn, P.; Shchapov, K.; Theriot, E. C.; Litchman, E.

10.1101/605899 — ecology — Posted on 2019-04-27

392 Direct transfer of a kinetochore between microtubules is fundamental to error correction mechanism

Doodhi, H.; Kasciukovic, T.; Gierlinski, M.; Li, S.; Clayton, L.; Tanaka, T. U.

10.1101/455873 — cell biology — Posted on 2019-04-27

393 A comparison between power spectral density and network metrics: an EEG study

Demuru, M.; La Cava, S. M.; Pani, S. M.; Fraschini, M.

10.1101/614271 — bioengineering — Posted on 2019-04-27

394 ciftify: A framework for surface-based analysis of legacy MR acquisitions

Dickie, E. W.; Anticevic, A.; Smith, D. E.; Coalson, T. S.; Manogaran, M.; Calarco, N.; Viviano, J. D.; Glasser, M. F.; Van Essen, D. C.; Voineskos, A. N.

10.1101/484428 — neuroscience — Posted on 2019-04-27

395 Structured Inhibitory Activity Dynamics During Learning

Arriaga, M.; Han, E. B.

10.1101/566257 — neuroscience — Posted on 2019-04-27

396 Benzoate-Tolerant Escherichia coli Strains from Experimental Evolution Lose the Gad Regulon, Multi-Drug Efflux Pumps, and Hydrogenases

Moore, J. P.; Li, H.; Engmann, M. L.; Bischof, K. M.; Kunka, K. S.; Harris, M. E.; Tancredi, A. C.; Ditmars, F. S.; Basting, P. J.; George, N. S.; Bhagwat, A. A.; Slonczewski, J. L.

10.1101/531178 — microbiology — Posted on 2019-04-27

397 DeepIS: deep learning framework for three-dimensional label-free tracking of immunological synapses

Lee, M.; Lee, Y.-H.; Song, J.; Kim, G.; Jo, Y.; Min, H.; Kim, C. H.; Park, Y.

10.1101/539858 — immunology — Posted on 2019-04-27

398 Evaluating fMRI-Based Estimation of Eye Gaze during Naturalistic Viewing

Son, J.; Ai, L.; Lim, R.; Xu, T.; Colcombe, S.; Franco, A.; Cloud, J.; LaConte, S.; Lisinski, J.; Klein, A.; Craddock, C.; Milham, M.

10.1101/347765 — neuroscience — Posted on 2019-04-26

399 Binding of an X-specific condensin correlates with a reduction in active histone modifications at gene regulatory elements

Street, L. A.; Morao, A. K.; Winterkorn, L. H.; Jiao, C.-Y.; Albritton, S. E.; Sadic, M.; Kramer, M.; Ercan, S.

10.1101/516419 — genomics — Posted on 2019-04-27

400 Long-distance dispersal, ice sheet dynamics, and mountaintop isolation underlie the genetic structure of glacier ice worms

Hotaling, S.; Shain, D. H.; Lang, S. A.; Bagley, R. K.; M., L.; Weisrock, D. W.; Kelley, J. L.

10.1101/463521 — evolutionary biology — Posted on 2019-04-26

401 Sex makes them sleepy: change in host reproductive status induces diapause in a parasitoid population experiencing harsh winters

Tougeron, K.; Brodeur, J.; van Baaren, J.; Renault, D.; Le Lann, C.

10.1101/371385 — ecology — Posted on 2019-04-26

402 A genetic hazard score to personalize prostate cancer screening, applied to population data

Huynh-Le, M.-P.; Fan, C. C.; Karunamuni, R.; Walsh, E. I.; Turner, E. L.; Lane, J. A.; Martin, R. M.; Neal, D. E.; Donovan, J. L.; Hamdy, F. C.; Parsons, J. K.; Eeles, R. A.; Easton, D. F.; Kote-Jarai, Z.; Amin Al Olama, A.; Benlloch Garcia, S.; Muir, K.; Gronberg, H.; Wiklund, F.; Aly, M.; Schleutker, J.; Sipeky, C.; Tammela, T. L.; Nordestgaard, B. G.; Key, T. J.; Travis, R. C.; Pharoah, P.; Pashayan, N.; Khaw, K.-T.; Thibodeau, S. N.; McDonnell, S. K.; Schaid, D. J.; Maier, C.; Vogel, W.; Luedeke, M.; Herkommer, K.; Kibel, A. S.; Cybulski, C.; Wokolorczyk, D.; Kluzniak, W.; Cannon-Albright,

10.1101/619718 — genetics — Posted on 2019-04-26

403 Hierarchical Domain Structure Reveals the Divergence of Activity among TADs and Boundaries

An, L.; Yang, T.; Yang, J.; Nuebler, J.; Xiang, G.; Hardison, R.; Li, Q.; Zhang, Y.

10.1101/361147 — bioinformatics — Posted on 2019-04-26

404 Assessing the impact of mindfulness attitudes on attentional quality through focused breath induction.

Franca, M.; Tanaka, G. K.; Cagy, M.; Ribeiro, P.; Velasques, B.; Gamboa, O. L.

10.1101/619817 — neuroscience — Posted on 2019-04-26

405 Polyglutamine-expanded androgen receptor disrupts muscle triad, calcium dynamics and the excitation-contraction coupling gene expression program

chivet, m.; marchioretti, c.; pirazzini, m.; piol, d.; Scaramuzzino, C.; Polanco, M.; Nath, S.; Zuccaro, E.; Nogara, L.; Canato, M.; Marcucci, L.; parodi, s.; Romanello, V.; Armani, A.; D'Antonio, M.; Sambataro, F.; Dassi, E.; Pegoraro, E.; Soraru', G.; Rinaldi, C.; Lieberman, A.; Blaauw, B.; Sandri, M.; Basso, m.; Pennuto, M.

10.1101/618405 — neuroscience — Posted on 2019-04-26

406 Selective Influence and Sequential Operations: A Research Strategy for Visual Search

Lowe, K. A.; Reppert, T. R.; Schall, J.

10.1101/619726 — neuroscience — Posted on 2019-04-26

407 Differential Expression of Mucins in Murine Olfactory Versus Respiratory Epithelium

Kennel, C.; Gould, E. A.; Larson, E. D.; Salcedo, E.; Vickery, T. W.; Restrepo, D.; Ramakrishnan, V. R.

10.1101/620757 — neuroscience — Posted on 2019-04-26

408 An Optimized Registration Workflow and Standard Geometric Space for Small Animal Brain Imaging

Ioanas, H.-I.; Marks, M.; Yanik, M. F.; Rudin, M.

10.1101/619650 — neuroscience — Posted on 2019-04-26

409 Tendon response to matrix unloading is determined by the patho-physiological niche

Wunderli, S. L.; Blache, U.; Beretta Piccoli, A.; Niederoest, B.; Holenstein, C. N.; Passini, F.; Silvan, U.; Bundgaard, L.; auf dem Keller, U.; Snedeker, J. G.

10.1101/620534 — molecular biology — Posted on 2019-04-26

410 Rotavirus NSP1 localizes in the nucleus to disrupt PML nuclear bodies during infection

Murphy, S. K.; Arnold, M. M.

10.1101/619932 — microbiology — Posted on 2019-04-26

411 Conservation genomic analysis reveals ancient introgression and declining levels of genetic diversity in Madagascar’s hibernating dwarf lemurs

Williams, R.; Blanco, M. B.; Poelstra, J. W.; Hunnicutt, K. E.; Comeault, A. A.; Yoder, A. D.

10.1101/620724 — genomics — Posted on 2019-04-26

412 Insect herbivory reshapes a native leaf microbiome

Humphrey, P. T.; Whiteman, N. K.

10.1101/620716 — ecology — Posted on 2019-04-26

413 Fitness barriers limit reversion of a proofreading-deficient coronavirus

Graepel, K. W.; Agostini, M. L.; Lu, X.; Sexton, N. R.; Denison, M. R.

10.1101/618249 — microbiology — Posted on 2019-04-26

414 Fast and robust animal pose estimation

Graving, J. M.; Chae, D.; Naik, H.; Li, L.; Koger, B.; Costelloe, B. R.; Couzin, I. D.

10.1101/620245 — animal behavior and cognition — Posted on 2019-04-26

415 Possible origin of the scrapie genome in small endogenous RNAs; studies on eight candidate species in 263K scrapie infected hamster brain

Lathe, R.

10.1101/620732 — neuroscience — Posted on 2019-04-26

416 Contributions of white matter connectivity and BOLD modulation to cognitive aging: A lifespan structure-function association study

Webb, C. E.; Rodrigue, K. M.; Hoagey, D. A.; Foster, C. M.; Kennedy, K. M.

10.1101/620443 — neuroscience — Posted on 2019-04-26

417 A Framework for Integrating Directed and Undirected Annotations to Build Explanatory Models of cis-eQTL Data.

Lamparter, D. F.; Bhatnagar, R.; Hebestreit, K.; Belgard, T. G.; Hanson-Smith, V.

10.1101/619452 — genetics — Posted on 2019-04-26

418 Factors affecting the survival of tree seedlings following shifting cultivation in the Eastern Himalaya

Teegalapalli, K.; Arthur, R.; Quader, S.; Datta, A.

10.1101/619981 — ecology — Posted on 2019-04-26

419 Multi-view Co-training for MicroRNA Prediction

Sheikh Hassani, M.; Green, J.

10.1101/620740 — bioinformatics — Posted on 2019-04-26

420 Connectal Coding: Discovering the Structures Linking Cognitive Phenotypes to Individual Histories

Vogelstein, J. T.; Bridgeford, E. W.; Pedigo, B. D.; Chung, J.; Levin, K.; Mensh, B.; Priebe, C. E.

10.1101/610501 — neuroscience — Posted on 2019-04-26

421 Multifactorial pathways facilitate resilience among kindergarteners at risk for dyslexia: A longitudinal behavioral and neuroimaging study

Zuk, J.; Dunstan, J.; Norton, E.; Yu, X.; Ozernov-Palchik, O.; Wang, Y.; Hogan, T. P.; Gabrieli, J.; Gaab, N.

10.1101/618298 — neuroscience — Posted on 2019-04-26

422 Modeling clinical phenotypes with protein function to explain the disease spectrum in patients with CHIP mutations

Madrigal, S. C.; McNeil, Z.; Shi, C.-h.; Patterson, C.; Scaglione, K. M.; Schisler, J. C.

10.1101/620591 — neuroscience — Posted on 2019-04-26

423 A microfabricated, 3D-sharpened silicon shuttle for insertion of flexible electrode arrays through dura mater into brain

Joo, H. R.; Fan, J. L.; Chen, S.; Pebbles, J. A.; Liang, H.; Chung, J. E.; Yorita, A. M.; Tooker, A. C.; Tolosa, V. M.; Geaghan-Breiner, C.; Roumis, D. K.; Liu, D. F.; Haque, R.; Frank, L. M.

10.1101/614685 — neuroscience — Posted on 2019-04-26

424 Serotonergic Modulation of a Visual Microcircuit in Drosophila melanogaster

Myers Gschweng, K. M.; Sampson, M. M.; Hardcastle, B. J.; Sizemore, T. R.; Dacks, A. M.; Frye, M. A.; Krantz, D. E.

10.1101/619759 — neuroscience — Posted on 2019-04-26

425 Human neutrophils produce antifungal extracellular vesicles against Aspergillus fumigatus

Shopova, I. A.; Belyaev, I.; Dasari, P.; Jahreis, S.; Stroe, M. C.; Cseresnyes, Z.; Medyukhina, A.; Svensson, C.-M.; Krueger, T.; Szeifert, V.; Nietzsche, S.; Conrad, T.; Kniemeyer, O.; von Lilienfeld-Toal, M.; Zipfel, P.; Ligeti, E.; Figge, M. T.; Brakhage, A. A.

10.1101/620294 — microbiology — Posted on 2019-04-26

426 Association and impact of hypertension defined using the 2017 AHA/ACC guidelines on the risk of atrial fibrillation in the Atherosclerosis Risk in Communities Study

Rattani, A.; Claxton, J. S.; Ali, M. K.; Chen, L. Y.; Soliman, E. Z.; Alonso, A.

10.1101/620393 — epidemiology — Posted on 2019-04-26

427 Supercoiling DNA optically

King, G. A.; Burla, F.; Peterman, E. J. G.; Wuite, G. J. L.

10.1101/620005 — biophysics — Posted on 2019-04-26

428 Loss of function in the autism and learning disabilities associated gene Nf1 disrupts corticocortical and corticostriatal functional connectivity in human and mouse

Shofty, B.; Bergmann, E.; Zur, G.; Asleh, J.; Bosak, N.; Kavushansky, A.; Castellanos, F. X.; Ben-Sira, L.; Packer, R. J.; Vezina, G.; Constantini, S.; Acosta, M. T.; Kahn, I.

10.1101/618223 — neuroscience — Posted on 2019-04-26

429 Altered directed functional connectivity of the right amygdala in depression: high-density EEG study

Damborska, A.; Rubega, M.; Honzirkova, E.; Bartecek, R.; Horinkova, J.; Fedorova, S.; Ondrus, S.; Michel, C.

10.1101/620252 — neuroscience — Posted on 2019-04-26

430 Mutual Information Analysis of Neural Representations of Speech in Noise in the Aging Midbrain

Zan, P.; Presacco, A.; Anderson, S.; Simon, J. Z.

10.1101/619528 — neuroscience — Posted on 2019-04-26

431 A putative enoyl-CoA hydratase contributes to biofilm formation and the antibiotic tolerance of Achromobacter xylosoxidans

Cameron, L. C.; Bonis, B.; Phan, C.; Kent, L.; Lee, A.; Hunter, R. C.

10.1101/620559 — microbiology — Posted on 2019-04-26

432 Animal personality shapes evolutionary trajectories via conserved genetic architecture

Royaute, R.; Hedrick, A.; Dochtermann, N.

10.1101/619411 — genetics — Posted on 2019-04-26

433 Environmental DNA for indigenous-led monitoring of a culturally important fish

Pochardt, M.; Allen, J. M.; Hart, T.; Miller, S. D. L.; Yu, D. W.; Levi, T.

10.1101/620500 — ecology — Posted on 2019-04-26

434 Subunit joining exposes nascent pre-40S rRNA for processing and quality control

Rai, J.; Parker, M. D.; Ghalei, H.; Johnson, M. C.; Karbstein, K.; Stroupe, M. E.

10.1101/617910 — biochemistry — Posted on 2019-04-26

435 CRK2-mediated control of ROS production by phosphorylation of the RBOHD C-terminus in Arabidopsis

Kimura, S.; Hunter, K.; Vaahtera, L.; Tran, C.; Vaattovaara, A.; Rokka, A.; Stolze, S. C.; Harzen, A.; Meissner, L.; Wilkens, M.; Hamann, T.; Toyota, M.; Nakagami, H.; Wrzaczek, M.

10.1101/618819 — plant biology — Posted on 2019-04-26

436 The de novo reference genome and transcriptome assemblies of the wild tomato species Solanum chilense

Stam, R.; Nosenko, T.; Hörger, A. C.; Stephan, W.; Seidel, M.; Kuhn, J. M. M.; Haberer, G.; Tellier, A.

10.1101/612085 — plant biology — Posted on 2019-04-26

437 A neural system for encoding odor-reward associations which influences approach behaviors

Gadziola, M. A.; Stetzik, L. A.; Milton, A. J.; Arakawa, K.; Wesson, D. W.

10.1101/617902 — neuroscience — Posted on 2019-04-26

438 Unraveling the relation between EEG-correlates of attentional orienting and sound localization performance: a diffusion model approach

Klatt, L.-I.; Schneider, D.; Schubert, A.-L.; Hanenberg, C.; Lewald, J.; Wascher, E.; Getzmann, S.

10.1101/616573 — neuroscience — Posted on 2019-04-26

439 Population structure and pangenome analysis of Enterobacter bugandensis uncover the presence of blaCTX-M-55, blaNDM-5 and blaIMI-1, along with sophisticated iron acquisition strategies

Matteoli, F. P.; Passarelli-Araujo, H.; Pedrosa-Silva, F.; Olivares, F. L.; Venancio, T. M.

10.1101/620682 — genomics — Posted on 2019-04-26

440 Adapterama II: Universal amplicon sequencing on Illumina platforms (TaggiMatrix)

Glenn, T. C.; Pierson, T. W.; Bayona-Vasquez, N. J.; Kieran, T. J.; Hoffberg, S. L.; Thomas, J. C.; Lefever, D. E.; Finger, J. W.; Gao, B.; Bian, X.; Louha, S.; Kolli, R. T.; Bentley, K.; Rushmore, J.; Wong, K.; Shaw, T. I.; Rothrock, M. J.; McKee, A. M.; Guo, T. L.; Mauricio, R.; Molina, M.; Cummings, B. S.; Lash, L. H.; Lu, K.; Gilbert, G. S.; Hubbell, S. P.; Faircloth, B. C.

10.1101/619544 — genomics — Posted on 2019-04-26

441 Coherent whole food web responses to outbreaking spruce budworm

Greyson-Gaito, C. J.; McCann, K. S.; Fründ, J.; Lucarotti, C. J.; Smith, M. A.; Eveleigh, E. S.

10.1101/615799 — ecology — Posted on 2019-04-26

442 Microtubule glycylation promotes basal body attachment to the cell cortex

Junker, A. D.; Soh, A. W. J.; O'Toole, E. T.; Meehl, J. B.; Guha, M.; Winey, M.; Honts, J. E.; Gaertig, J.; Pearson, C. G.

10.1101/620476 — cell biology — Posted on 2019-04-26

443 Prognostic Analysis of Histopathological Images Using Pre-Trained Convolutional Neural Networks

Lu, L.; Daigle, B.

10.1101/620773 — bioinformatics — Posted on 2019-04-26

444 DNA methylation-based immune cell deconvolution in solid tumors

Liang, C.; Yu, X.; Li, B.; Chen, Y. A.; Conejo-Garcia, J.; Wang, X.

10.1101/619965 — bioinformatics — Posted on 2019-04-26

445 Modeling the competing effects of the immune system and EMT on tumor development

Bergman, D. R.; Karikomi, M. K.; Nie, Q.; MacLean, A. L.

10.1101/615971 — systems biology — Posted on 2019-04-26

446 Coordinated circadian timing through the integration of local inputs in Arabidopsis thaliana

Greenwood, M.; Domijan, M.; Gould, P. D.; Hall, A. J. W.; Locke, J. C. W.

10.1101/617803 — plant biology — Posted on 2019-04-26

447 Liquid-liquid phase separation and liquid-to-solid transition mediate α-synuclein amyloid fibril containing hydrogel formation

Ray, S.; Singh, N.; Pandey, S.; Kumar, R.; Gadhe, L.; Datta, D.; Patel, K.; Mahato, J.; Navalkar, A.; Panigrahi, R.; Chatterjee, D.; Maiti, S.; Bhatia, S.; Mehra, S.; Singh, A.; Gerez, J.; Chowdhury, A.; Kumar, A.; Padinhateeri, R.; Riek, R.; Krishnamoorthy, G.; Maji, S.

10.1101/619858 — neuroscience — Posted on 2019-04-26

448 Rapid sensory integration in orexin neurons governs probability of future movements

Karnani, M. M.; Schöne, C.; Bracey, E. F.; Gonzalez, J. A.; Viskaitis, P.; Adamantidis, A.; Burdakov, D.

10.1101/620096 — neuroscience — Posted on 2019-04-26

449 An anticipated optimization approach to macromolecular crystallization

Gorrec, F.

10.1101/620328 — molecular biology — Posted on 2019-04-26

450 Simultaneous ribosome profiling of human host cells infected with Toxoplasma gondii

Holmes, M. J.; Shah, P.; Wek, R. C.; Sullivan, W. J.

10.1101/619916 — microbiology — Posted on 2019-04-26

451 Immunodietica: A data-driven approach to investigate interactions between diet and autoimmune disorders

Gershteyn, I. M.; Ferreira, L. M. R.

10.1101/619700 — immunology — Posted on 2019-04-26

452 Integrating patterns of thermal tolerance and phenotypic plasticity with population genetics to improve understanding of vulnerability to warming in a widespread copepod

Sasaki, M. C.; Dam, H.

10.1101/619775 — evolutionary biology — Posted on 2019-04-26

453 A Large-scale Study Reveals 24 hour Operational Rhythms in Hospital Treatment

Ruben, M. D.; Francey, L. J.; Guo, Y.; Wu, G.; Cooper, E. B.; Shah, A. S.; Hogenesch, J. B.; Smith, D. F.

10.1101/617944 — epidemiology — Posted on 2019-04-26

454 Complexity and ultrastructure of infectious extracellular vesicles from cells infected by nonenveloped virus

Yang, J. E.; Rossignol, E. D.; Chang, D.; Zaia, J.; Forrester, I.; Saulsbery, H.; Nicastro, D.; Jackson, W. T.; Bullitt, E.

10.1101/618306 — cell biology — Posted on 2019-04-26

455 N-WASP regulates the mobility of the B cell receptor and co-receptors during signaling activation

Rey-Suarez, I.; Wheatley, B.; Koo, P.; Shu, Z.; Mochrie, S.; Song, W.; Shroff, H.; Upadhyaya, A.

10.1101/619627 — biophysics — Posted on 2019-04-26

456 Identifying neoantigens for cancer vaccines by personalized deep learning of individual immunopeptidomes

Tran, N. H.; Qiao, R.; Xin, L.; Chen, X.; Shan, B.; Li, M.

10.1101/620468 — bioinformatics — Posted on 2019-04-26

457 Machine learning predicts early-onset acute organ failure in critically ill patients with sickle cell disease

Mohammed, A.; Podila, P. S.; Davis, R. L.; Ataga, K. I.; Hankins, J. S.; Kamaleswaran, R.

10.1101/614941 — bioinformatics — Posted on 2019-04-26

458 Efficient treatment of a preclinical inflammatory bowel disease model with engineered bacteria

Ferenczi, S.; Horvath, I.; Szeocs, N.; Grozer, Z.; Kuti, D.; Juhasz, B.; Winkler, Z.; Pankotai, T.; Sukosd, F.; Kovacs, K.; Szallasi, Z.

10.1101/619536 — synthetic biology — Posted on 2019-04-26

459 Hindbrain V2a neurons impose rhythmic activity on motor neurons in an in vitro reticulospinal circuit

Bubnys, A.; Kandel, H.; Kow, L.-M.; Pfaff, D. W.; Tabansky, I.

10.1101/620674 — neuroscience — Posted on 2019-04-26

460 Impaired EAT-4 Vesicular Glutamate Transporter Leads to Defective Nocifensive Response of Caenorhabditis elegans to Noxious Heat

Leonelli, S.; Nkambeu, B.; Beaudry, F.

10.1101/620302 — neuroscience — Posted on 2019-04-26

461 Epidemic growth rates and host movement patterns shape management performance for pathogen spillover at the wildlife-livestock interface

Manlove, K. R.; Sampson, L. M.; Borremans, B.; Cassirer, E. F.; Miller, R. S.; Pepin, K.; Besser, T. E.; Cross, P.

10.1101/617290 — epidemiology — Posted on 2019-04-26

462 Are the Matrix Metalloproteinases 2 and 9 beeing expressed in the mucosa of the rat small intestine during its intrauterine and postnatal life development?

dos Reis, C. A.; Gomes, J. R. R.

10.1101/619767 — developmental biology — Posted on 2019-04-26

463 Maize Kernel Development Stage the Primary Factor in Differential Gene Expression in Response to Two Methods of Field Inoculation with Aspergillus flavus

Wahl, N. J.; Murray, S. C.; Zhang, H.-B.; Zhang, M.; Dickens, C. M.; Isakeit, T. S.

10.1101/617241 — plant biology — Posted on 2019-04-26

464 Anterior cingulate cortex and ventral hippocampal inputs to the basolateral amygdala selectively control generalized fear

Ortiz, S.; Latsko, M. S.; Fouty, J. L.; Dutta, S.; Adkins, J. M.; Jasnow, A. M.

10.1101/620237 — neuroscience — Posted on 2019-04-26

465 Zebrafish use visual cues and geometric relationships to form a spatial memory

Yashina, K.; Tejero-Cantero, A.; Herz, A.; Baier, H.

10.1101/620575 — neuroscience — Posted on 2019-04-26

466 Isoform specificity of PKMs during long-term facilitation in Aplysia is mediated through stabilization by KIBRA

Ferguson, L.; Hu, J.; Cai, D.; Chen, S.; Dunn, T. W.; Glanzman, D. L.; Schacher, S.; Sossin, W. S.

10.1101/620633 — neuroscience — Posted on 2019-04-26

467 Medial prefrontal cortex guides goal-directed decision-making about hunger and thirst

Eiselt, A.-K.; Chen, J.; Arnold, J.; Kim, T.; Sternson, S. M.

10.1101/620690 — neuroscience — Posted on 2019-04-26

468 Pupil-associated states modulate excitability but not stimulus selectivity in primary auditory cortex

Schwartz, Z. P.; Buran, B. N.; David, S. V.

10.1101/619619 — neuroscience — Posted on 2019-04-26

469 Evolutionary dynamics of culturally transmitted, fertility-reducing traits

Wodarz, D.; Stipp, S.; Komarova, N.

10.1101/619882 — evolutionary biology — Posted on 2019-04-26

470 Slow life-history strategies are associated with negligible actuarial senescence in western Palearctic salamanders

Cayuela, H.; Olgun, K.; Angelini, C.; Uzum, N.; Peyronel, O.; Miaud, C.; Avci, A.; Lemaitre, J.-F.; Schmidt, B. R.

10.1101/619494 — ecology — Posted on 2019-04-26

471 Direct Nucleosome Binding of Borealin Secures Chromosome Association and Function of the Chromosomal Passenger complex

Abad, M. A.; Ruppert, J. G.; Buzuk, L.; Wear, M.; Zou, J.; Webb, K. M.; Kelly, D. A.; Voigt, P.; Rappsilber, J.; Earnshaw, W. C.; Jeyaprakash, A. A.

10.1101/620385 — cell biology — Posted on 2019-04-26

472 Museum epigenomics: characterizing cytosine methylation in historic museum specimens

Rubi, T. L.; Knowles, L. L.; Dantzer, B.

10.1101/620583 — genomics — Posted on 2019-04-26

473 Population genomics reveals complex patterns of immune gene evolution in monarch butterflies (Danaus plexippus)

Tan, W.-H.; Mongue, A. J.; de Roode, J. C.; Gerardo, N. M.; Walters, J. R.

10.1101/620013 — evolutionary biology — Posted on 2019-04-26

474 Population-specific effect of Wolbachia on the cost of fungal infection in spider mites

Zele, F.; Altintas, M.; Lopes dos Santos, I. F.; Cakmak, I.; Magalhaes, S.

10.1101/620310 — ecology — Posted on 2019-04-26

475 De novo Classification of Mouse B Cell Types using Surfaceome Proteotype Maps

van Oostrum, M.; Mueller, M.; Klein, F.; Bruderer, R.; Zhang, H.; Pedrioli, P.; Reiter, L.; Tsapogas, P.; Rolink, A.; Wollscheid, B.

10.1101/620344 — biochemistry — Posted on 2019-04-26

476 Light-sheet imaging and graph-theoretical analysis of antidepressant action in the larval zebrafish brain network

Burgstaller, J.; Hindinger, E.; Gesierich, B.; Baier, H.

10.1101/618843 — neuroscience — Posted on 2019-04-26

477 RST1 and RIPR connect the cytosolic RNA exosome to the Ski complex in Arabidopsis

Lange, H.; Ndecky, S. Y. A.; Gomez-Diaz, C.; Pflieger, D.; Butel, N.; Zumsteg, J.; Kuhn, L.; Piermaria, C.; Chicher, J.; Christie, M.; Karaaslan, E. S.; Lang, P. L. M.; Weigel, D.; Vaucheret, H.; Hammann, P.; Gagliardi, D.

10.1101/617894 — molecular biology — Posted on 2019-04-26

478 Sociobehavioural characteristics and HIV incidence in 29 sub-Saharan African countries: Unsupervised machine learning analysis using the Demographic and Health Surveys

Merzouki, A.; Estill, J.; Tal, K.; Keiser, O.

10.1101/620450 — epidemiology — Posted on 2019-04-26

479 The scaling of genome size and cell size limits maximum rates of photosynthesis with implications for ecological strategies

Roddy, A.; Theroux-Rancourt, G.; Abbo, T.; Brodersen, C. R.; Jensen, B. M.; Jiang, G.-F.; Thompson, R. A.; Kuebbing, S. E.; Simonin, K. A.

10.1101/619585 — ecology — Posted on 2019-04-26

480 Chromosome disentanglement driven via optimal compaction of loop-extruded brush structures

Brahmachari, S.; Marko, J. F.

10.1101/616102 — biophysics — Posted on 2019-04-26

481 Longitudinal analysis of blood markers reveals progressive loss of resilience and predicts ultimate limit of human lifespan

Pyrkov, T. V.; Avchaciov, K.; Tarkhov, A. E.; Menshikov, L. I.; Gudkov, A. V.; Fedichev, P. O.

10.1101/618876 — systems biology — Posted on 2019-04-26

482 The Drosophila metallopeptidase superdeath decouples apoptosis from the activation of the ER stress response

Palu, R. A. S.; Chow, C. Y.

10.1101/620492 — genetics — Posted on 2019-04-26

483 Workplace Harassment and risk of Depression Among Adults in the United States.

Aduse-Poku, L.

10.1101/618355 — epidemiology — Posted on 2019-04-26

484 Membrane remodeling by the lytic fragment of sticholysin II: implications for the toroidal pore model

Mesa-Galloso, H.; Valiente, P. A.; Epand, R. F.; Lanio, M. E.; Epand, R. M.; Alvarez, C. M.; Tieleman, D. P.; Ros Quincoces, U. L.

10.1101/620336 — biophysics — Posted on 2019-04-26

485 Increased Dynamics of α-Synuclein Fibrils by β-Synuclein Leads to Reduced Seeding and Cytotoxicity

Yang, X.; Williams, J.; Yan, R.; Mouradian, M. M.; Baum, J.

10.1101/620401 — biophysics — Posted on 2019-04-26

486 Retromer repletion with AAV9-VPS35 restores endosomal function in the mouse hippocampus

Qureshi, Y.; Berman, D. E.; Klein, R. L.; Patel, V. M.; Simoes, S.; Kannan, S.; Cox, R.; Waksal, S.; Stevens, B.; Petsko, G. A.; Small, S. A.

10.1101/618496 — neuroscience — Posted on 2019-04-26

487 Reducing malaria burden and accelerating elimination with long-lasting systemic insecticides: a modeling study of three potential use cases

Selvaraj, P.; Suresh, J.; Wenger, E. A.; Bever, C. A.; Gerardin, J.

10.1101/615773 — epidemiology — Posted on 2019-04-26

488 Drosophila Snazarus regulates a lipid droplet population at plasma membrane-droplet contacts in adipocytes

Ugrankar, R.; Bowerman, J.; Hariri, H.; Chandra, M.; Chen, K.; Bossanyi, M.-F.; Datta, S.; Rogers, S.; Eckert, K.; Vale, G.; Victoria, A.; Fresquez, J.; McDonald, J.; Jean, S.; Collins, B.; Henne, M.

10.1101/620278 — cell biology — Posted on 2019-04-26

489 Stability of Aβ-fibril fragments in the presence of fatty acids

Xi, W.; Vanderford, E. K.; Liao, Q.; Hansmann, U.

10.1101/620518 — biophysics — Posted on 2019-04-26

490 Estimating the Relative Probability of Direct Transmission between Infectious Disease Patients

Van Ness, S. E.; Lee, R. S.; Sebastiani, P.; Horsburgh, C. R.; Jenkins, H. E.; White, L. F.

10.1101/612945 — epidemiology — Posted on 2019-04-26

491 The impact of geographic targeting of oral cholera vaccination in sub-Saharan Africa: a modeling study

Lee, E. C.; Azman, A. S.; Kaminsky, J.; Moore, S. M.; McKay, H.; Lessler, J.

10.1101/617076 — epidemiology — Posted on 2019-04-26

492 A Bayesian Monte Carlo approach for predicting the spread of infectious diseases

Stojanovic, O.; Leugering, J.; Pipa, G.; Ghozzi, S.; Ullrich, A.

10.1101/617795 — epidemiology — Posted on 2019-04-26

493 Relationship between gut microbiota and circulating metabolites in population-based cohorts

Vojinovic, D.; Radjabzadeh, D.; Kurilshikov, A.; Amin, N.; Wijmenga, C.; Franke, L.; Ikram, M. A.; Uitterlinden, A. G.; Zhernakova, A.; Fu, J.; Kraaij, R.; van Duijn, C. M.

10.1101/617431 — epidemiology — Posted on 2019-04-26

494 The ‘breakpoint’ in transmission for soil-transmitted helminths: dynamical behaviour near the equilibria and the impact of infected human migration

J. Hardwick, R.; Vegvari, C.; E. Truscott, J.; M. Anderson, R.

10.1101/619908 — epidemiology — Posted on 2019-04-26

495 Neurocognitive mechanisms of d-cycloserine augmented single-session exposure therapy for anxiety

Reinecke, A.; Nickless, A.; Browning, M.; Harmer, C.

10.1101/615757 — clinical trials — Posted on 2019-04-26

496 Validation of a CRISPR/cas9-based technology platform for examining specific immune gene functions in an experimental murine model of IBD

Wang, R.; Graham, S.; Sun, N.; McCarthy, D.; Peng, R.; Erickson, J.; Zhu, X.; Wurbel, M. A.; Dunstan, R.; Chung, N.; Fiebiger, E.; Ghayur, T.; Gu, J.

10.1101/619791 — immunology — Posted on 2019-04-26

497 Immunogenomic landscape of hematological malignancies

Dufva, O.; Polonen, P.; Bruck, O.; Keranen, M.; Mehtonen, J.; Kumar, A.; Heckman, C.; Siitonen, S.; Granberg, K.; Leivonen, S.-K.; Meriranta, L.; Leppa, S.; Nykter, M.; Lohi, O.; Heinaniemi, M.; Mustjoki, S.

10.1101/618918 — immunology — Posted on 2019-04-26

498 The Moorfields AMD Database Report 2 - Fellow Eye Involvement with Neovascular Age-related Macular Degeneration

Fasler, K.; Moraes, G.; Fu, D. J.; Wagner, S. K.; Gokhale, E.; Kortuem, K.; Chopra, R.; Faes, L.; Preston, G.; Pontikos, N.; Patel, P.; Tufail, A.; Lee, A.; Balaskas, K.; Keane, P. A.

10.1101/615252 — epidemiology — Posted on 2019-04-26

499 BioBankRead: Data pre-processing in Python for UKBiobank clinical data

Schneider-Luftman, D.; Crum, W.

10.1101/569715 — epidemiology — Posted on 2019-04-26

500 Estimating genetic and non-genetic effects for host susceptibility, infectivity and recoverability using temporal epidemic data

Pooley, C. M.; Bishop, S. C.; Doeschl-Wilson, A. B.; Marion, G.

10.1101/618363 — epidemiology — Posted on 2019-04-26

501 Co-infections by non-interacting pathogens are not independent and require new tests of interaction

Hamelin, F. M.; Allen, L. J.; Bokil, V. A.; Gross, L. J.; Hilker, F. M.; Jeger, M. J.; Manore, C. A.; Power, A. G.; Rua, M. A.; Cunniffe, N. J.

10.1101/618900 — epidemiology — Posted on 2019-04-26

502 Google searches accurately forecast RSV hospitalizations

Althouse, B. M.; Weinberger, D. M.; Scarpino, S. V.; Pitzer, V.; Ayers, J. W.; Wenger, E.; Fung, I. C.-H.; Dredze, M.; Hu, H.

10.1101/607119 — epidemiology — Posted on 2019-04-26

503 Safety and Tolerability of Bacteriophage Therapy in Severe Staphylococcus aureus Infection

Petrovic Fabijan, A.; Lin, R. C.; Ho, J.; Maddocks, S.; Iredell, J. R.; Westmead Bacteriophage Therapy Team & AmpliPhi Bio,

10.1101/619999 — clinical trials — Posted on 2019-04-26

504 A Novel, Versatile Speculum-free Callascope for Clinical Examination and Self-Visualization of the Cervix

Asiedu, M.; Agudogo, J. S.; Dotson, M. E.; Krieger, M. S.; Schmitt, J. W.; Huchko, M.; Suneja, G.; Proeschold-Bell, R. J.; Smith, J. S.; Jenson, D.; Hogan, W.; Ramanujam, N.

10.1101/618348 — clinical trials — Posted on 2019-04-26

505 Bifunctional Small Molecule Ligands of K-Ras Induce Its Association with Immunophilin Proteins

Zhang, Z.; Shokat, K.

10.1101/619551 — cancer biology — Posted on 2019-04-26

506 A convolutonal neural network for predicting transcriptional regulators of genes in Arabidopsis transcriptome data reveals classification based on positive regulatory interactions

MacLean, D.

10.1101/618926 — bioinformatics — Posted on 2019-04-26

507 Graded striatal learning factors enable switches between goal-directed and habitual modes, by reassigning behavior control to the fastest-computed representation that predicts reward

Patrick, S.; Bullock, D.

10.1101/619445 — neuroscience — Posted on 2019-04-26

508 Modeling the Switching behavior of Functional Connectivity Microstates (FCμstates) as a Novel Biomarker for Mild Cognitive Impairment

Dimitriadis, S. I.; Lopez, M.-E.; Maestu, F.; Pereda, E.

10.1101/619437 — neuroscience — Posted on 2019-04-26

509 On the Mathematics of Populations

Gomes, G.

10.1101/612366 — epidemiology — Posted on 2019-04-26

510 Strong self-regulation and widespread facilitative interactions between genera of phytoplankton

Picoche, C.; Barraquand, F.

10.1101/617811 — ecology — Posted on 2019-04-26

511 Co-reviewing and ghostwriting by early career researchers in the peer review of manuscripts

McDowell, G. S.; Knutsen, J.; Graham, J.; Oelker, S. K.; Lijek, R. S.

10.1101/617373 — scientific communication and education — Posted on 2019-04-26

512 Geographic variation in the genetic basis of resistance to leaf rust in locally adapted ecotypes of the biofuel crop switchgrass (Panicum virgatum)

VanWallendael, A.; Bonnette, J.; Juenger, T. E.; Fritschi, F. B.; Fay, P. A.; Mitchell, R. B.; Lloyd-Reilley, J.; Rouquette, F.; Bergstrom, G. C.; Lowry, D. B.

10.1101/619148 — genomics — Posted on 2019-04-26

513 REMoDNaV: Robust Eye Movement Detection for Natural Viewing

Dar, A. H.; Wagner, A. S.; Hanke, M.

10.1101/619254 — bioinformatics — Posted on 2019-04-26

514 A curated knowledgebase enabling a network perspective on endocrine disrupting chemicals and their biological systems-level perturbations

Karthikeyan, B. S.; Ravichandran, J.; Mohanraj, K.; Vivek-Ananth, R. P.; Samal, A.

10.1101/619163 — bioinformatics — Posted on 2019-04-26

515 Untapped viral diversity in global soil metagenomes

Graham, E. B.; Paez-Espino, D.; Brislawn, C.; Hofmockel, K. S.; Wu, R.; Kyrpides, N. C.; Jansson, J. K.; McDermott, J. E.

10.1101/583997 — microbiology — Posted on 2019-04-26

516 Evaluation of DNA extraction methods on individual helminth egg and larval stages for whole genome sequencing

Doyle, S. R.; Sankaranarayanan, G.; Berger, D.; Jimenez Castro, P. D.; Collins, J. B.; Crellen, T.; Durque-Correa, M. A.; Ellis, P.; Jaleta, T. G.; Laing, R.; Maitland, K.; McCarthy, C.; Moundai, T.; Softley, B.; Thiele, E.; Ouakou, P. T.; Tushabe, J. V.; Webster, J. P.; Weiss, A. J.; Lok, J. B.; Devaney, E.; Kaplan, R. M.; Cotton, J. A.; Berriman, M.; Holroyd, N.

10.1101/616672 — genomics — Posted on 2019-04-26

517 Mapping of multiple complementary sex determination loci in a parasitoid wasp

Matthey-Doret, C.; van der Kooi, C. J.; Jeffries, D. L.; Bast, J.; Dennis, A. B.; Vorburger, C.; Schwander, T.

10.1101/620229 — genomics — Posted on 2019-04-26

518 Epigenetic bookmarking of H2S exposure in Caenorhabditis elegans

Fawcett, E. M.; Johnson, J. K.; Braden, C.; Garcia, E.; Miller, D. L.

10.1101/619734 — genetics — Posted on 2019-04-26

519 Genetic modification of primary human B cells generates translationally-relevant models of high-grade lymphoma

Caeser, R.; Di Re, M.; Krupka, J. A.; Gao, J.; Lara-Chica, M.; Dias, J. M. L.; Cooke, S. L.; Fenner, R.; Usheva, Z.; Runge, H.; Beer, P. A.; Eldaly, H.; Pak, H.-K.; Park, C.-S.; Vassiliou, G.; Huntly, B. J. P.; Mupo, A.; Bashford-Rogers, R. J.; Hodson, D. J.

10.1101/618835 — cancer biology — Posted on 2019-04-26

520 GenMap: Fast and Exact Computation of Genome Mappability

Pockrandt, C.; Alzamel, M.; Iliopoulos, C. S.; Reinert, K.

10.1101/611160 — bioinformatics — Posted on 2019-04-26

521 Robust Genome Editing of Single-Base PAM Targets with Engineered ScCas9 Variants

Chatterjee, P.; Jakimo, N.; Jacobson, J. M.

10.1101/620351 — bioengineering — Posted on 2019-04-26

522 First near complete haplotype phased genome assembly of River buffalo (Bubalus bubalis)

Sudhakar, A.; Kothandaraman, H.; Nayee, N.; Saha, S.; Baghel, D. S.; Kishore, G.; Peddamma, S.; Singh, R. B.; Schatz, M.

10.1101/618785 — genomics — Posted on 2019-04-26

523 Tau pathology in cognitively normal older adults: Associations with brain atrophy and cognitive decline

Ziontz, J.; Bilgel, M.; Shafer, A.; Moghekar, A.; Elkins, W.; Helphrey, J.; Gomez, G.; June, D.; McDonald, M. A.; Dannals, R. F.; Azad, B. B.; Ferrucci, L.; Wong, D. F.; Resnick, S. M.

10.1101/611186 — neuroscience — Posted on 2019-04-26

524 A ride in the park: Cycling in different outdoor environments modulates the auditory evoked potentials

Scanlon, J. E. M.; Redman, E. X.; Kuziek, J. W. P.; Mathewson, K. E.

10.1101/455394 — neuroscience — Posted on 2019-04-26

525 Dopamine modulates learning-related changes in dynamic striatal-cortical connectivity in Parkinson’s disease

Gerraty, R. T.; Sharp, M. E.; Buch, A.; Bassett, D. S.; Shohamy, D.

10.1101/619478 — neuroscience — Posted on 2019-04-26

526 A multi-omic analysis of optineurin proteinopathy in a yeast model suggests the involvement of lipid metabolism in Amyotrophic Lateral Sclerosis

Bean, D. M.; Hnatova, S.; Muelleder, M.; Magalhaes, S.; Nightingale, D. J. H.; Lilley, K. S.; Ralser, M.; Nunes, A.; Goodfellow, B. J.; Oliver, S. G.

10.1101/605998 — systems biology — Posted on 2019-04-26

527 EEG resting-state large-scale brain network dynamics are related to depressive symptoms

Damborska, A.; Tomescu, M.; Honzirkova, E.; Bartecek, R.; Horinkova, J.; Fedorova, S.; Ondrus, S.; Michel, C.

10.1101/619031 — neuroscience — Posted on 2019-04-26

528 Cellular properties of intrinsically photosensitive retinal ganglion cells during postnatal development

Lucas, J. A.; Schmidt, T. M.

10.1101/619387 — neuroscience — Posted on 2019-04-26

529 Brain BOLD MRI O2 and CO2 stress testing: Implications for perioperative neurocognitive disorder following surgery

Mutch, W. A. C.; El-Gabalawy, R.; Ryner, L.; Puig, J.; Essig, M.; Kilborn, K.; Fidler, K.; Graham, M. R.

10.1101/619361 — neuroscience — Posted on 2019-04-26

530 Morphological variation in Blommersia pelvic shape coincides with muscular architecture and parallels genus phylogenetic evolution

Santos-Santos, J. H.; Guinovart-Castan, M.; Vieites, D.

10.1101/586248 — evolutionary biology — Posted on 2019-04-26

531 After the Honeymoon, the Divorce: Unexpected Outcomes of Disease Control Measures Against Endemic Infections

Hollingsworth, B.; Okamoto, K.; Lloyd, A.

10.1101/608653 — epidemiology — Posted on 2019-04-26

532 MetaNovo: a probabilistic approach to peptide and polymorphism discovery in complex mass spectrometry datasets

Potgieter, M. G.; Nel, A. J.; Tabb, D. L.; Fortuin, S.; Garnett, S.; Blackburn, J.; Mulder, N.

10.1101/605550 — bioinformatics — Posted on 2019-04-26

533 Male competition and the evolution of mating and life history traits in experimental populations of Aedes aegypti

Qureshi, A.; Aldersley, A.; Hollis, B.; Ponlawat, A.; Cator, L.

10.1101/619072 — evolutionary biology — Posted on 2019-04-26

534 The continuing impact of an ancient polyploidy on the genomes of teleosts

Conant, G.

10.1101/619205 — evolutionary biology — Posted on 2019-04-26

535 Angiosperm speciation speeds up near the poles

Igea, J.; Tanentzap, A. J.

10.1101/619064 — evolutionary biology — Posted on 2019-04-26

536 About samples, giving examples: Optimized Single Molecule Localization Microscopy

Jimenez, A.; Friedl, K.; Leterrier, C.

10.1101/568295 — cell biology — Posted on 2019-04-26

537 HIV chromatin is a preferred target for drugs that bind in the DNA minor groove

Little, Donald W.; Schafer, Samuel J.;Anderson, John N.;

10.1101/618090 — molecular biology — Posted on 2019-04-26

538 Microarray screening of differentially expressed genes after up-regulating miR-205 or down-regulating miR-141 in cervical cancer cells

Fang, X.; yao, t.

10.1101/618041 — cancer biology — Posted on 2019-04-26

539 Deprivation of dietary fiber enhances susceptibility of mice to cryptosporidiosis

Oliveira, B. C. M.; Bresciani, K. D. S.; Widmer, G.

10.1101/620203 — microbiology — Posted on 2019-04-26

540 A new method for inferring timetrees from temporally sampled molecular sequences

Miura, S.; Tamura, K.; Kosakovsky Pond, S. L.; Huuki, L. A.; Priest, J.; Deng, J.; Kumar, S.

10.1101/620187 — evolutionary biology — Posted on 2019-04-26

541 Workshops increase invasive species reports to EDDMapS in the Mid-Atlantic United States

Wallace, R. D.; Bargeron, C. T.; Swearingen, J.; LaForest, J. H.; Moorhead, D. J.; Luo, X.

10.1101/620138 — scientific communication and education — Posted on 2019-04-26

542 Dropout from maternity continuum of care and associated factors among women in Debre Markos town, Northwest Ethiopia: Community based cross sectional study

Sewnet, N.; Araya, B. M.; Asaye, M. M.

10.1101/620120 — epidemiology — Posted on 2019-04-26

543 Assessment of Tuberculosis incidence and treatment success rates of the indigenous Maka community in Paraguay

Froberg, J.; Sequera, G.; Tostmann, A.; Aguirre, S.; Magis-Escurra, C.

10.1101/620161 — epidemiology — Posted on 2019-04-26

544 Learning supervised embeddings for large scale sequence comparisons

Kimothi, D.; Biyani, P.; Hogan, J. M.; Soni, A.; Kelly, W.

10.1101/620153 — bioinformatics — Posted on 2019-04-26

545 A high-precision hybrid algorithm for predicting eukaryotic protein subcellular localization

Zhang, D.; Huang, H.; Bai, X.; Fang, X.; Zhang, Y.

10.1101/620179 — bioinformatics — Posted on 2019-04-26

546 Effect of Septoria brown spot on soybean yield in Illinois

Lin, H.-A.; Villamil, M. B.; Mideros, S.

10.1101/620112 — plant biology — Posted on 2019-04-26

547 Glutamine Synthetase-1 induces autophagy-lysosomal degradation of Huntingtin aggregates and ameliorates animal motility in a Drosophila model for HD

Vernizzi, L.; Paiardi, C.; Licata, G.; Vitali, T.; Santarelli, S.; Raneli, M.; Manelli, V.; Rizzetto, M.; Gioria, M.; Pasini, M. E.; Grifoni, D.; Vanoni, M. A.; Gellera, C.; Taroni, F.; Bellosta, P.

10.1101/618629 — cell biology — Posted on 2019-04-26

548 Modern clinical Mtb strains leverage the type I IFN pathway for a pro-inflammatory response in the host

Shankaran, D.; Arumugam, P.; Gandotra, S.; Rao, V. K.

10.1101/594655 — immunology — Posted on 2019-04-26

549 Complex-Traits Genetics Virtual Lab: A community-driven web platform for post-GWAS analyses

Cuellar-Partida, G.; Lundberg, M.; Kho, P. F.; D'Urso, S.; Gutierrez-Mondragon, L. F.; Ngo, T.; Hwang, L.-D.

10.1101/518027 — genetics — Posted on 2019-04-26

550 RPW8/HR Repeats Control NLR Activation in A. thaliana

Barragan, C.; Wu, R.; Kim, S.-T.; Xi, W.; Habring, A.; Hagmann, J.; Van de Weyer, A.-L.; Zaidem, M.; Ho, W. W. H.; Wang, G.; Bezrukov, I.; Weigel, D.; Chae, E.

10.1101/559864 — genetics — Posted on 2019-04-26

551 A genetically-encoded toolkit of functionalized nanobodies against fluorescent proteins for visualizing and manipulating intracellular signalling

Prole, D. L.; Taylor, C. W.

10.1101/544700 — cell biology — Posted on 2019-04-26

552 A pitfall for machine learning methods aiming to predict across cell types

Schreiber, J.; Singh, R.; Bilmes, J.; Noble, W. S.

10.1101/512434 — bioinformatics — Posted on 2019-04-26

553 Rapid, Low-Cost Detection of Water Contaminants Using Regulated In Vitro Transcription

Alam, K.; Jung, J.; Verosloff, M.; Clauer, P.; Lee, J. W.; Capdevila, D.; Pasten, P.; Giedroc, D.; Collins, J.; Lucks, J.

10.1101/619296 — synthetic biology — Posted on 2019-04-26

554 singleCellHaystack: Finding surprising genes in single cell transcriptome data

Vandenbon, A.; Diez, D.

10.1101/557967 — bioinformatics — Posted on 2019-04-26

555 Finding high-quality metal ion-centric regions across the worldwide Protein Data Bank

Yao, S.; Moseley, H. N. B.

10.1101/619809 — molecular biology — Posted on 2019-04-26

556 A broad-host-range CRISPRi toolkit for silencing gene expression in Burkholderia

Hogan, A. M.; Rahman, A. S. M. Z.; Lightly, T. L.; Cardona, S. T.

10.1101/618413 — microbiology — Posted on 2019-04-26

557 Assembly-free single-molecule nanopore sequencing recovers complete virus genomes from natural microbial communities

Beaulaurier, J.; Luo, E.; Eppley, J.; Den Uyl, P.; Dai, X.; Turner, D. J.; Pendleton, M.; Juul, S.; Harrington, E.; DeLong, E. F.

10.1101/619684 — microbiology — Posted on 2019-04-26

558 EphB1 in Endothelial Cells Regulates Caveolae Formation and Endocytosis

Tiruppathi, C.; Regmi, S. C.; Wang, D.-M.; Mo, G. C. H.; Toth, P. T.; Vogel, S. M.; Stan, R. V.; Henkemeyer, M.; Minshall, R. D.; Malik, A. B.

10.1101/619510 — cell biology — Posted on 2019-04-26

559 Preparation of anti-HER-2 antibody PLGA polymer nano-ultrasound contrast agent In vitro targeting experiment

Smith, J.; Lin, J.; Snider, M.

10.1101/619742 — bioengineering — Posted on 2019-04-26

560 Macromolecular crowding links ribosomal protein gene dosage to growth rate in Vibrio cholerae.

Soler-Bistue, A.; Aguilar-Pierle, S.; Garcia-Garcera, M.; Val, M.-E.; Sismeiro, O.; Varet, H.; Sieira, R.; Krin, E.; Skovgaard, O.; Comerci, D. J.; Rocha, E. P.; Mazel, D.

10.1101/619304 — microbiology — Posted on 2019-04-25

561 Unique Features of Sub-Cortical Circuits in A Macaque Model of Congenital Blindness

Magrou, L.; Barone, P.; Markov, N. T.; Scheeren, G.; Killackey, H. P.; Giroud, P.; Berland, M.; Knoblauch, K.; Dehay, C.; Kennedy, H.

10.1101/609636 — neuroscience — Posted on 2019-04-25

562 Prediction of pyrazinamide resistance in Mycobacterium tuberculosis using structure-based machine learning approaches.

Carter, J.; Walker, T. M.; Walker, A. S.; Whitfield, M.; Morlock, G. P.; Peto, T. E.; Posey, J. E.; Crook, D. W.; Fowler, P. W.

10.1101/518142 — microbiology — Posted on 2019-04-25

563 Predicting the conservation status of Europe’s Data Deficient sharks and rays

Walls, R. H. L.; Dulvy, N. K.

10.1101/614776 — ecology — Posted on 2019-04-25

564 The knockout of the HMG- Box Domain of the porcine SRY-gene by CRISPR/Cas RNP microinjection causes sex reversal in gene-edited pigs

Kurtz, S.; Frenzel, A.; Lucas-Hahn, A.; Hassel, P.; Becker, R.; Ziegler, M.; Nowak-Imialek, M.; Schlegelberger, B.; Goehring, G.; Niemann, H.; Petersen, B.

10.1101/617589 — developmental biology — Posted on 2019-04-25

565 Optimal Mass Transport Kinetic Modeling for Head and Neck DCE-MRI: Initial Analysis

Elkin, R.; Nadeem, S.; LoCastro, E.; Paudyal, R.; Hatzoglou, V.; Lee, N.; Shukla-Dave, A.; Deasy, J. O.; Tannenbaum, A.

10.1101/612770 — systems biology — Posted on 2019-04-25

566 Understanding multivariate brain activity: evaluating the effect of voxelwise noise correlations on population codes in functional magnetic resonance imaging

Zhang, R.-Y.; Wei, X.-X.; Kay, K.

10.1101/592618 — neuroscience — Posted on 2019-04-25

567 Prey abundance drives habitat occupancy by jaguars in Amazonian floodplain river islands

Rabelo, R. M.; Aragon, S.; Bicca-Marques, J. C.

10.1101/555052 — ecology — Posted on 2019-04-25

568 Single cell RNA-seq reveals cellular diversity and developmental characteristics of human infant retina

Zhong, J.; Chen, D.; Hu, F.; Chen, F.; Xu, Z.; Fang, J.; Xu, J.; Wang, S.; Liang, L.; Chai, C.; Ding, X.; Zhu, J.; Ding, P.; Xia, J.; Jiang, S.; Li, W.; Gao, Y.; Zhang, J.; Li, J.; Xu, P.; Gao, F.; Wang, D.; Zhang, D.; Huang, J.; Qu, S.; Zhang, S.; Wu, J.; Sun, X.

10.1101/617555 — cell biology — Posted on 2019-04-25

569 The Alzheimer’s Disease Metabolome: Effects of Sex and APOE ε4 genotype

Arnold, M.; Nho, K.; Kueider-Paisley, A.; Massaro, T.; Brauner, B.; Mahmoudiandehkordi, S.; Louie, G.; Moseley, M. A.; Thompson, J. W.; St John-Williams, L.; Tenenbaum, J. D.; Blach, C.; Chang, R.; Brinton, R. D.; Baillie, R.; Han, X.; Trojanowski, J. Q.; Shaw, L. M.; Weiner, M. W.; Trushina, E.; Toledo, J. B.; Krumsiek, J.; Doraiswamy, P. M.; Saykin, A. J.; Kaddurah-Daouk, R.; Kastenmuller, G.; Alzheimers Disease Neuroimaging Initiative, ; Alzheimers Disease Metabolomics Consortium,

10.1101/585455 — bioinformatics — Posted on 2019-04-25

570 Nerve Excitability Differences in Slow and Fast Motor Axons of the Rat: more than just Ih

Bell, J. M.; Lorenz, C.; Jones, K. E.

10.1101/613984 — neuroscience — Posted on 2019-04-25

571 A flexible and generalizable model of online latent-state learning

Cochran, A. L.; Cisler, J. M.

10.1101/443234 — neuroscience — Posted on 2019-04-25

572 Big root approximation of site-scale vegetation water uptake

Bouda, M.

10.1101/559237 — plant biology — Posted on 2019-04-25

573 EMULSION: transparent and flexible multiscale stochastic models in epidemiology

Picault, S.; Huang, Y.-L.; Sicard, V.; Arnoux, S.; Beaunee, G.; Ezanno, P.

10.1101/563791 — epidemiology — Posted on 2019-04-25

574 Simple study designs in ecology produce inaccurate estimates of biodiversity responses

Christie, ; Amano, T.; Martin, P. A.; Shackelford, G. E.; Simmons, B. I.; Sutherland, W. J.

10.1101/612101 — ecology — Posted on 2019-04-25

Tiek, D. M.; Khatib, S. A.; Trepicchio, C. J.; Heckler, M. M.; Divekar, S. D.; Sarkaria, J. N.; Glasgow, E.; Riggins, R. B.

10.1101/558775 — cancer biology — Posted on 2019-04-25

576 The Genetic Chain Rule for Probabilistic Kinship Estimation

Helfer, B. S.; Fremont-Smith, P.; Ricke, D. O.

10.1101/202879 — bioinformatics — Posted on 2019-04-25

577 Laboratory Methods Supporting Measles surveillance in Queensland, Australia, 2010-2017

McMahon, J. L.; Northill, J. A.; Finger, M.; Lyon, M.; Lambert, S. B.; Mackay, I. M.

10.1101/472175 — microbiology — Posted on 2019-04-25

578 Adapterama III: Quadruple-indexed, double/triple-enzyme RADseq libraries (2RAD/3RAD)

Bayona-Vasquez, N. J.; Glenn, T. C.; Kieran, T. J.; Pierson, T. W.; Hoffberg, S. L.; Scott, P. A.; Bentley, K. E.; Finger, J. W.; Louha, S.; Troendle, N.; Diaz-Jaimes, P.; Mauricio, R.; Faircloth, B. C.

10.1101/205799 — genomics — Posted on 2019-04-25

579 RPW8/HR Repeats Control NLR Activation in A. thaliana

Barragan, C.; Wu, R.; Kim, S.-T.; Xi, W.; Habring, A.; Hagmann, J.; Van de Weyer, A.-L.; Zaidem, M.; Ho, W. W. H.; Wang, G.; Bezrukov, I.; Weigel, D.; Chae, E.

10.1101/559864 — genetics — Posted on 2019-04-25

580 Synthetic Promoter Design in Escherichia coli based on Generative Adversarial Network

Wang, Y.; Wang, H.; Liu, L.; Wang, X.

10.1101/563775 — bioinformatics — Posted on 2019-04-25

581 A Genome-engineered Bioartificial Implant for Autoregulated Anti-Cytokine Drug Delivery

Choi, Y.-R.; Collins, K.; Springer, L.; Pferdehirt, L.; Ross, A.; Wu, C.-L.; Moutos, F.; Harasymowicz, N.; Brunger, J.; Pham, C.; Guilak, F.

10.1101/535609 — synthetic biology — Posted on 2019-04-25

582 Evolution at the edge of expanding populations

Deforet, M.; Carmona-Fontaine, C.; Korolev, K. S.; Xavier, J. B.

10.1101/221390 — evolutionary biology — Posted on 2019-04-25

583 dsDNA Phage Andromeda with Quasispecies-like Genomic Hypervariability Establishes a Novel Phylogenetic Branch Within the Autographivirinae Subfamily

Magill, D. J.; Skvortsov, T.; Kulakov, L. A.

10.1101/619015 — microbiology — Posted on 2019-04-25

584 Gene Therapy for Follistatin Mitigates Systemic Metabolic Inflammation and Post-Traumatic Osteoarthritis in High-Fat Diet-Induced Obese Mice

Tang, R.; Harasymowicz, N.; Wu, C.-L.; Collins, K.; Choi, Y.-R.; Oswald, S.; Guilak, F.

10.1101/619239 — physiology — Posted on 2019-04-25

585 Elimination of reference mapping bias reveals robust immune related allele-specific expression in cross-bred sheep

Salavati, M.; Bush, S. J.; Palma-Vera, S.; McCulloch, M. E. B.; Hume, D.; Clark, E. L.

10.1101/619122 — genomics — Posted on 2019-04-25

586 Recessive genetic effects on type 2 diabetes-related metabolites in a consanguineous population

Demirkan, A.; Liu, J.; Amin, N.; van Klinken, J. B.; van Dijk, K. W.; van Duijn, C. M.

10.1101/619262 — genetics — Posted on 2019-04-25

587 Origin of a novel CYP20A1 lncRNA through 23 Alu exaptations in the human lineage creates a potential multi-miRNA sponge

Bhattacharya, A.; Jha, V.; Singhal, K.; Fatima, M.; Singh, D.; Chaturvedi, G.; Dholakia, D.; Kutum, R.; Bakken, T. E.; Seth, P.; Pillai, B.; Mukerji, M.

10.1101/618645 — evolutionary biology — Posted on 2019-04-25

588 Telomere dysfunction represses HNF4α leading to impaired hepatocyte development and function

Niero, E. L.; Fok, W. C.; Vessoni, A. T.; Brenner, K. A.; Batista, L. F. Z.

10.1101/619601 — developmental biology — Posted on 2019-04-25

589 Correlative evidence for co-regulation of phosphorus and carbon exchanges with symbiotic fungus in the arbuscular mycorrhizal Medicago truncatula

Konecny, J.; Hrselova, H.; Bukovska, P.; Hujslova, M.; Jansa, J.

10.1101/618850 — plant biology — Posted on 2019-04-25

590 Syntenizer 3000: Synteny-based analysis of orthologous gene groups

Moslemi, C.; Skovbjerg, C. K.; Moeskjaer, S.; Andersen, S. U.

10.1101/618678 — bioinformatics — Posted on 2019-04-25

591 Control Theory Concepts for Modeling Uncertainty in Enzyme Kinetics of Biochemical Networks

Miskovic, L.; Tokic, M.; Savoglidis, G.; Hatzimanikatis, V.

10.1101/618777 — systems biology — Posted on 2019-04-25

592 Evidence for the rhythmic perceptual sampling of auditory scenes

Kayser, C.

10.1101/618652 — neuroscience — Posted on 2019-04-25

593 No atypical white-matter structures in grapheme- or color-sensitive areas in synesthetes

Weiss, F.; Greenlee, M. W.; Volberg, G.

10.1101/618611 — neuroscience — Posted on 2019-04-25

594 CTCF binding strength modulates chromatin architecture through the changes of the local nucleosome repeat length

Clarkson, C. T.; Deeks, E. A.; Samarista, R.; Zhurkin, V. B.; Teif, V. B.

10.1101/618827 — genomics — Posted on 2019-04-25

595 Versatile polyketide biosynthesis platform for production of aromatic compounds in yeast

Jakociunas, T.; Klitgaard, A. K.; Romero-Suarez, D.; Petzold, C. J.; Gin, J. W.; Tong, Y.; Frandsen, R. J. N.; Weber, T.; Lee, S. Y.; Krogh Jensen, M.; Keasling, J. D.

10.1101/618751 — synthetic biology — Posted on 2019-04-25

596 supFunSim: spatial filtering toolbox for EEG

Rykaczewski, K.; Nikadon, J.; Duch, W.; Piotrowski, T. J.

10.1101/618694 — neuroscience — Posted on 2019-04-25

597 Effect of inbreeding on type 2 diabetes-related metabolites in a Dutch genetic isolate

Demirkan, A.; Liu, J.; Amin, N.; van Dijk, K. W.; van Duijn, C. M.

10.1101/618801 — genetics — Posted on 2019-04-25

598 MNC-RED a Chemically Defined Method to Produce Enucleated Red Blood Cells from Adult Peripheral Blood Mononuclear Cells

Zhang, S. E.; Olivier, E. E.; Yan, Z. E.; Suzuka, S. E.; Roberts, K. E.; Wang, K. E.; Bouhassira, E. E.

10.1101/616755 — bioengineering — Posted on 2019-04-25

599 Calibrating seed-based heuristics to map short DNA reads

Filion, G. J.; Cortini, R.; Zorita, E. V.

10.1101/619155 — bioinformatics — Posted on 2019-04-25

600 Genome-wide CRISPR Screens Reveal Genetic Mediators of Cereblon Modulator Toxicity in Primary Effusion Lymphoma

Patil, A.; Manzano, M.; Gottwein, E.

10.1101/619312 — cancer biology — Posted on 2019-04-25

601 Multi-Template Matching: a versatile tool for object-localization in microscopy images

Thomas, L. S.; Gehrig, J.

10.1101/619338 — bioinformatics — Posted on 2019-04-25

602 Force-dependent facilitated dissociation can generate protein-DNA catch bonds

Dahlke, K.; Zhao, J.; Sing, C. E.; Banigan, E. J.

10.1101/619171 — biophysics — Posted on 2019-04-25

603 GABA-A signaling maintains melanocyte stem cell quiescence in larval zebrafish

Allen, J. R.; Skeath, J. B.; Johnson, S. L.

10.1101/619056 — developmental biology — Posted on 2019-04-25

604 Interaction between DNA damage response, translation and apoptosome determines cancer susceptibility to TOP2 poisons

Awah, C. U.; Chen, L.; Bansal, M.; Mahajan, A.; Winter, J.; Lad, M.; Warnke, L.; Gonzalez-Buendia, E.; Park, C.; Zhang, D.; Feldstein, E.; Yu, D.; Zannikou, M.; Balyasnikova, I.; Martuscello, R.; Konermann, S.; Gyorffy, B.; Burdett, K.; Scholtens, D.; Stupp, R.; Ahmed, A.; Hsu, P.; Sonabend, A. M.

10.1101/614024 — cancer biology — Posted on 2019-04-25

605 Isotropic expansion of external environment induces tissue elongation and collective cell alignment

Koyama, H.; Fujimori, T.

10.1101/619189 — biophysics — Posted on 2019-04-25

606 Human 28s rRNA 5’ terminal derived small RNA inhibits ribosomal protein mRNA levels

Li, S.

10.1101/618520 — biochemistry — Posted on 2019-04-25

607 Efficient consideration of coordinated water molecules improves computational protein-protein and protein-ligand docking

Pavlovicz, R. E.; Park, H.; DiMaio, F.

10.1101/618603 — biochemistry — Posted on 2019-04-25

608 Reconstructing the ecology of a Jurassic pseudoplanktonic megaraft colony

Hunter, A. W.; Mitchell, E. G.; Casenove, D.; Mayers, C.

10.1101/566844 — paleontology — Posted on 2019-04-25

609 Identification of neuronal lineages in the Drosophila peripheral nervous system with a novel multi-spectral lineage tracing system

Veling, M. W.; Li, Y.; Veling, M. T.; Litts, C.; Michki, N.; Liu, H.; Cai, D.; Ye, B.

10.1101/618264 — neuroscience — Posted on 2019-04-25

610 Environmental and epigenetic regulation of Rider retrotransposons in tomato

Benoit, M.; Drost, H.-G.; Catoni, M.; Gouil, Q.; Lopez-Gomollon, S.; Baulcombe, D. C.; Paszkowski, J.

10.1101/517508 — plant biology — Posted on 2019-04-25

611 Structure-guided design of novel orthosteric inhibitors of integrin αIIbβ3 that prevent thrombosis but preserve hemostasis

Adair, B. D.; Alonso, J. L.; van Agthoven, J.; Hayes, V.; Ahn, H. S.; Yu, I.-S.; Lin, S.-W.; Poncz, M.; Xiong, J.-P.; Arnaout, M. A.

10.1101/509299 — cell biology — Posted on 2019-04-25

612 A microfluidic device for inferring metabolic landscapes in yeast monolayer colonies

Marinkovic, Z. S.; Vulin, C.; Acman, M.; Song, X.; Di Meglio, J. M.; Lindner, A.; Hersen, P.

10.1101/527846 — biophysics — Posted on 2019-04-25

613 Modulation of large-scale cortical coupling by transcranial alternating current stimulation

Schwab, B. C.; Misselhorn, J.; Engel, A. K.

10.1101/484014 — neuroscience — Posted on 2019-04-25

614 Anticipatory coadaptation of ankle stiffness and neural feedback for standing balance

Le Mouel, C.; Brette, R.

10.1101/506493 — neuroscience — Posted on 2019-04-25

615 CBP/EP300 acetylates and stabilizes the stress-responsive Heat Shock Factor 2, a process compromised in Rubinstein-Taybi syndrome

de Thonel, A.; Ahlskog, J. K.; Abane, R.; Pires, G.; Dubreuil, V.; Bertelet, J.; Aalto, A. L.; Naceri, S.; Cordonnier, M.; Benasolo, C.; Sanial, M.; Duchateau, A.; Vihervaara, A.; Puustinen, M. C.; Miozzo, F.; Henry, M.; Bouvier, D.; Concordet, J.-P.; Fergelot, P.; Lebigot, E.; Verloes, A.; Gressens, P.; Lacombe, D.; Gobbo, J.; Garrido, C.; Westerheide, S. D.; Petitjean, M.; Taboureau, O.; Rodrigues-Lima, F.; Lancaster, M.; Passemart, S.; Saberan Djoneidi, D.; Sistonen, L.; Mezger, V.

10.1101/481457 — developmental biology — Posted on 2019-04-25

616 Degron-tagged reporters probe membrane topologyand enable the specific labelling of membrane-wrapped structures

Beer, K. B.; Fazeli, G.; Judasova, K.; Irmisch, L.; Causemann, J.; Mansfeld, J.; Wehman, A. M.

10.1101/442103 — cell biology — Posted on 2019-04-25

617 A role for the auxin precursor anthranilic acid in root gravitropism via regulation of PIN-FORMED protein polarity and relocalization in Arabidopsis

Doyle, S. M.; Rigal, A.; Grones, P.; Karady, M.; Barange, D. K.; Majda, M.; Parizkova, B.; Karampelias, M.; Zwiewka, M.; Pencik, A.; Almqvist, F.; Ljung, K.; Novak, O.; Robert, S.

10.1101/422733 — plant biology — Posted on 2019-04-25

618 Planar cell polarity pathway and development of the human visual cortex

Shin, J.; Ma, S.; Hofer, E.; Patel, Y.; Roshchupkin, G.; Sousa, A. M.; Jian, X.; Gottesmann, R.; Mosley, T. H.; Fornage, M.; Saba, Y.; Pirpamer, L.; Schmidt, R.; Schmidt, H.; Mazoyer, B.; Carrion-Castillo, A.; Bis, J.; Li, S.; Yang, Q.; Luciano, M.; Karama, S.; Lewis, L.; Bastin, M.; Harris, M. A.; Deary, I.; Wardlaw, J. M.; Scholz, M.; Loeffler, M.; Witte, V.; Beyer, F.; Villringer, A.; Adams, H. H.; Ikrum, M. A.; Kremen, W. S.; Gillespie, N. A.; the ENIGMA Consortium, ; Sestan, N.; Pausova, Z.; Seshadri, S.; Paus, T.; the neuroCHARGE Working Group,

10.1101/404558 — neuroscience — Posted on 2019-04-25

619 Explore or reset? Pupil diameter transiently increases in self-chosen switches between cognitive labor and leisure in either direction

Algermissen, J.; Bijleveld, E.; Jostmann, N. B.; Holland, R. W.

10.1101/379214 — neuroscience — Posted on 2019-04-25

620 Comparing fMRI inter-subject correlations between groups using permutation tests

Tohka, J.; Pollick, F. E.; Pajula, J.; Kauppi, J.-P.

10.1101/370023 — neuroscience — Posted on 2019-04-25

621 GPIF constrains Polycomb Repressive Complex 2 activity in germ cells

Ragazzini, R.; Perez-Palacios, R.; Baymaz, I.; Zielinski, D.; Michaud, A.; Givelet, M.; Borsos, M.; Jansen, P. W.; Servant, N.; Torres-Padilla, M.-E.; Bourc'His, D.; Fouchet, P.; Vermeulen, M.; Margueron, R.

10.1101/619080 — developmental biology — Posted on 2019-04-25

622 Modulating pathogenesis with Mobile-CRISPRi

Rosenberg, O.; Qu, J.-X.; Prasad, N. K.; Peters, J.; Looney, M.; Yu, M.; Lyden, A.; Chen, S.; Crawford, E.; Silvis, M.

10.1101/618637 — microbiology — Posted on 2019-04-25

623 The structural basis for RNA selectivity by the IMP family of RNA binding proteins

Biswas, J.; Patel, V. L.; Bhaskar, V.; Chao, J. A.; Singer, R. H.; Eliscovich, C.

10.1101/618587 — biochemistry — Posted on 2019-04-25

624 O-glycosylation of SPL transcription factors regulates plant developmental transitions downstream of miR156

Mutanwad, K. V.; Neumayer, N.; Freitag, C.; Zangl, I.; Lucyshyn, D.

10.1101/618744 — plant biology — Posted on 2019-04-25

625 Basement membrane regulates fibronectin organization using sliding focal adhesions driven by a contractile winch

Lu, J.; Doyle, A. D.; Yoshinari, S.; Wang, S.; Bodendorfer, M. A.; Zheng, M.; Yamada, K.

10.1101/618686 — cell biology — Posted on 2019-04-25

626 Proteoliposomes as energy transferring nanomaterials: enhancing the spectral range of light-harvesting proteins using lipid-linked chromophores

Hancock, A. M.; Meredith, S. A.; Connell, S. D. A.; Jeuken, L. J. C.; Adams, P. G.

10.1101/609255 — biophysics — Posted on 2019-04-25

627 A lipophilicity-based energy function for membrane-protein modelling and design

Weinstein, J. Y.; Elazar, A.; Fleishman, S. J.

10.1101/615658 — biochemistry — Posted on 2019-04-25

628 Glutamine Synthetase-1 induces autophagy-lysosomal degradation of Huntingtin aggregates and ameliorates animal motility in a Drosophila model for HD

Vernizzi, L.; Paiardi, C.; Licata, G.; Vitali, T.; Santarelli, S.; Raneli, M.; Manelli, V.; Rizzetto, M.; Gioria, M.; Pasini, M. E.; Grifoni, D.; Vanoni, M. A.; Gellera, C.; Taroni, F.; Bellosta, P.

10.1101/618629 — cell biology — Posted on 2019-04-25

629 Axonal Na+ channels detect and transmit levels of input synchrony in local brain circuits

Zbili, M.; Rama, S.; Yger, P.; Inglebert, Y.; Boumedine-Guignon, N.; Fronzaroli-Molinieres, L.; Brette, R.; Russier, M.; Debanne, D.

10.1101/618710 — neuroscience — Posted on 2019-04-25

630 Plasmodium secretion induces hepatocyte lysosome exocytosis and promotes parasite entry

Vijayan, K.; Cestari, I.; Mast, F. D.; Glennon, E. K. K.; McDermott, S. M.; Kain, H. S.; Brokaw, A. M.; Aitchison, J. D.; Stuart, K.; Kaushansky, A.

10.1101/618397 — cell biology — Posted on 2019-04-25

631 Differential Expression Gene Explorer (DrEdGE): A tool for generating interactive online data visualizations for exploration of quantitative transcript abundance datasets

Tintori, S. C.; Golden, P.; Goldstein, B.

10.1101/618439 — genomics — Posted on 2019-04-25

632 A network of microRNAs acts to promote cell cycle exit and differentiation of human pancreatic endocrine cells

Jin, W.; Mulas, F.; Gaertner, B.; Sui, Y.; Wang, J.; Zeng, C.; Vinckier, N.; Wang, A.; Nguyen-Ngoc, K.-V.; Chiou, J.; Kaestner, K. H.; Frazer, K.; Carrano, A. C.; Shih, H.-P.; Sander, M.

10.1101/618330 — developmental biology — Posted on 2019-04-25

633 Sing cell RNA-seq reveals cellular diversity and developmental characteristics of human infant retina

Zhong, J.; Chen, D.; Hu, F.; Chen, F.; Xu, Z.; Fang, J.; Xu, J.; Wang, S.; Liang, L.; Chai, C.; Ding, X.; Zhu, J.; Ding, P.; Xia, J.; Liang, S.; Li, W.; Gao, Y.; Zhang, J.; Li, J.; Xu, P.; Gao, F.; Wang, D.; Zhang, D.; Huang, J.; Qu, S.; Zhang, S.; Wu, J.; Sun, X.

10.1101/617555 — cell biology — Posted on 2019-04-25

634 Collective intelligence defines biological functions in Wikipedia as communities in the hidden protein connection network

Zinovyev, A.; Czerwinska, U.; Cantini, L.; Barillot, E.; Frahm, K. M.; Shepelyansky, D.

10.1101/618447 — systems biology — Posted on 2019-04-25

635 FRMPD2: a novel GluN2A-interacting scaffold protein in synaptic excitatory transmission

Lu, X.; Wang, X.; Zhang, H.; Tian, X.

10.1101/403360 — neuroscience — Posted on 2019-04-25

636 Identification of neuronal lineages in the Drosophila peripheral nervous system with a novel multi-spectral lineage tracing system

Veling, M. W.; Li, Y.; Veling, M. T.; Litts, C.; Michki, N.; Liu, H.; Cai, D.; Ye, B.

10.1101/618264 — neuroscience — Posted on 2019-04-25

637 Superficial bound of the depth limit of 2-photon imaging in mouse brain

Takasaki, K.; Abbasi-Abl, R.; Waters, J.

10.1101/618454 — neuroscience — Posted on 2019-04-25

638 Alterations of the pulmonary immunity are independent of spontaneous pneumonia in an experimental model of ischemic stroke

Farris, B. Y.; Monaghan, K. L.; Amend, C. D.; Zheng, W.; Hu, H.; Coad, J. E.; Ren, X.; Wan, E. C. K.

10.1101/618314 — immunology — Posted on 2019-04-25

639 Transcriptomics of monarch butterflies (Danaus plexippus) reveals strong differential gene expression in response to host plant toxicity, but weak response to parasite infection

Tan, W.-H.; Acevedo, T.; Harris, E. V.; Alcaide, T. Y.; Walters, J. R.; Hunter, M. D.; Gerardo, N. M.; de Roode, J. C.

10.1101/618546 — genomics — Posted on 2019-04-25

640 Single-cell imaging reveals unexpected heterogeneity of TERT expression across cancer cell lines

Rowland, T.; Dumbovic, G.; Hass, E. P.; Rinn, J.; Cech, T. R.

10.1101/618769 — cancer biology — Posted on 2019-04-25

641 Gephebase, a Database of Genotype-Phenotype Relationships for natural and domesticated variation in Eukaryotes

Courtier-Orgogozo, V.; Arnoult, L.; Prigent, S. R.; Wiltgen, S.; Martin, A.

10.1101/618371 — bioinformatics — Posted on 2019-04-25

642 NeuRiPP: Neural network identification of RiPP precursor peptides

Santos, E. L. d. L.

10.1101/616060 — bioinformatics — Posted on 2019-04-25

643 Mass Cytometry Study on the Heterogeneity in Cellular Association and Cytotoxicity of Silver Nanoparticles in Human Immune Cells

Ha, M. K.; Choi, J.-S.; Gerelkhuu, Z.; Kwon, S. J.; Song, J.; Lee, Y.; Kim, Y.-E.; Yoon, T. H.

10.1101/617332 — biochemistry — Posted on 2019-04-25

644 A neural basis of probabilistic computation in visual cortex

Walker, E. Y.; Cotton, R. J.; Ma, W. J.; Tolias, A. S.

10.1101/365973 — neuroscience — Posted on 2019-04-25

645 Sex makes them sleepy: change in host reproductive status induces diapause in a parasitoid population experiencing harsh winters

Tougeron, K.; Brodeur, J.; van Baaren, J.; Renault, D.; Le Lann, C.

10.1101/371385 — ecology — Posted on 2019-04-25

646 Adoption and consequences of new light-fishing technology (LEDs) on Lake Tanganyika, East Africa

Mgana, H.; Kraemer, B. M.; O'Reilly, C. M.; Staehr, P. A.; Kimirei, I. A.; Apse, C.; Leisher, C.; Ngoile, M.; McIntyre, P. B.

10.1101/619007 — scientific communication and education — Posted on 2019-04-25

647 Exogenous Melatonin accelerates seed germination in cotton(Gossypium hirsutum L.)

Xiao, S.; Liu, L.; Wang, H.; Li, D.; Bai, Z.; Zhang, Y.; Sun, H.; Zhang, K.; Li, C.

10.1101/618959 — plant biology — Posted on 2019-04-25

648 Gene expression is associated with virulence in murine macrophages infected with Leptospira spp

Araujo Junior, E. C. d.; Garcia, L. E.; Araujo, M. J.; Oliveira-Junior, I. S.; Arnold, D. R.; Lopes, F. L.; Marinho, M.

10.1101/619023 — molecular biology — Posted on 2019-04-25

649 Thermophilic PHB depolymerase of Stenotrophomonas sp., an isolate from the plastic contaminated site is best purified on Octyl-Sepharose CL-4B

Sayyed, R.; Wani, S. J.; Shaikh, S. S.; Al-Harthi, H. F.; Syed, A.; El-Enshasy, H. A.

10.1101/618967 — microbiology — Posted on 2019-04-25

650 Intrauterine exposure to hyperglycaemia in pregnancy and risk of adiposity in the offspring at 10 years of age - A community based retrospective cohort study in Sri Lanka

Herath, H.; Herath, R.; Wickremasinghe, R.

10.1101/618991 — epidemiology — Posted on 2019-04-25

651 Childhood conditions, pathways to entertainment work and current practices of female entertainment workers in Cambodia Baseline findings from the Mobile Link trial

Brody, C.; Chhoun, P.; Tuot, S.; Swendeman, D.; Yi, S.

10.1101/618983 — epidemiology — Posted on 2019-04-25

652 An In-Silico Investigation of Menthol Metabolism

Limpanuparb, T.; Lorpaiboon, W.; Chinsukserm, K.

10.1101/618975 — biochemistry — Posted on 2019-04-25

653 Long-Term Outcomes of Pediatric Graves Disease Patients Treated with Anti-Thyroid Drugs: Experience from a Taiwan Medical Center

Chiang, Y.-T.; Ting, W.-H.; Huang, C.-Y.; Huang, S.-K.; Chan, C.-I.; Cheng, B.-W.; Lin, C.-H.; Wu, Y.-L.; Hung, C.-M.; Li, H.-J.; Chan, C.-J.; Lee, Y.-J.

10.1101/618942 — physiology — Posted on 2019-04-25

654 Water storage and irrigation practices associated with cannabis production drive seasonal patterns of water extraction and use in Northern California watersheds

Dillis, C.; McIntee, C.; Grantham, T.; Butsic, V.; Le, L.; Grady, K.

10.1101/618934 — ecology — Posted on 2019-04-25

655 Molecular dynamics simulation of proton-transfer coupled rotations in ATP synthase FO motor

Kubo, S.; Niina, T.; Takada, S.

10.1101/618504 — biophysics — Posted on 2019-04-25

656 The temporal dynamics of background selection in non-equilibrium populations

Torres, R.; Stetter, M. G.; Hernandez, R.; Ross-Ibarra, J.

10.1101/618389 — evolutionary biology — Posted on 2019-04-25

657 Deep Residual Learning for Neuroimaging: An application to Predict Progression to Alzheimer’s Disease

Abrol, A.; Bhattarai, M.; Fedorov, A.; Du, Y.; Plis, S.; Calhoun, V.

10.1101/470252 — neuroscience — Posted on 2019-04-24

658 Biodistribution and inflammatory response of intracranial delivery of scintillating nanoparticles

Fischer, M.; Zimmerman, A.; Zhang, E.; Kolis, J.; Dickey, A.; Burdette, M. K.; Afaghpour-Becklund, M.; Chander, P.; Foulger, S.; Brigman, J.; Weick, J.

10.1101/609354 — bioengineering — Posted on 2019-04-24

659 An Indexing Theory for Working Memory based on Fast Hebbian Plasticity

Fiebig, F.; Herman, P.; Lansner, A.

10.1101/334821 — neuroscience — Posted on 2019-04-24

660 Action kinematics as an organising principle in the cortical control of human hand movement

Kolasinski, J.; Dima, D. C.; Mehler, D. M. A.; Stephenson, A.; Valadan, S.; Kusmia, S.; Rossiter, H. E.

10.1101/613323 — neuroscience — Posted on 2019-04-24

661 Stable Pom1 clusters form a glucose-modulated concentration gradient that regulates mitotic entry

Allard, C. A. H.; Opalko, H. E.; Moseley, J. B.

10.1101/547224 — cell biology — Posted on 2019-04-24

662 GAPIN: Grouped and Aligned Protein Interface Networks

Araujo, B. M.; Coelho, A. L.; Silveira, S. d. A.; Romanelli, J. P. R.; Minardi, R. C. d. M.; da Silveira, C. H.

10.1101/520833 — bioinformatics — Posted on 2019-04-24

663 Decreased viability and neurite length in neural cells treated with chitosan-dextran sulfate nanocomplexes

Zamproni, L. N.; Teixeira, D.; Alliegro, A. A.; Maugeri, I. L.; des Rieux, A.; Porcionatto, M.

10.1101/616144 — neuroscience — Posted on 2019-04-24

664 Gene regulatory network reconstruction incorporating 3D chromosomal architecture reveals key transcription factors and DNA elements driving neural lineage commitment

Malysheva, V.; Mendoza-Parra, M. A.; Blum, M.; Spivakov, M.; Gronemeyer, H.

10.1101/303842 — molecular biology — Posted on 2019-04-24

665 Analysis of the structural variability of topologically associated domains as revealed by Hi-C

Sauerwald, N.; Singhal, A.; Kingsford, C.

10.1101/498972 — genomics — Posted on 2019-04-24

666 Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism

Satterstrom, F. K.; Kosmicki, J. A.; Wang, J.; Breen, M. S.; De Rubeis, S.; An, J.-Y.; Peng, M.; Collins, R. L.; Grove, J.; Klei, L.; Stevens, C.; Reichert, J.; Mulhern, M.; Artomov, M.; Gerges, S.; Sheppard, B.; Xu, X.; Bhaduri, A.; Norman, U.; Brand, H.; Schwartz, G.; Nguyen, R.; Guerrero, E.; Dias, C.; Aleksic, B.; Anney, R. J.; Barbosa, M.; Bishop, S.; Brusco, A.; Bybjerg-Grauholm, J.; Carracedo, A.; Chan, M. C. Y.; Chiocchetti, A.; Chung, B.; Coon, H.; Cuccaro, M.; Curro, A.; Dalla Bernardina, B.; Doan, R.; Domenici, E.; Dong, S.; Fallerini, C.; Fernandez-Prieto, M.; Ferrero, G. B.; Freit

10.1101/484113 — genetics — Posted on 2019-04-24

667 Field assessment of precocious maturation in salmon parr using ultrasound imaging

Nevoux, M.; Marchand, F.; Forget, G.; Huteau, D.; Tremblay, J.; Destouches, J.-P.

10.1101/425561 — ecology — Posted on 2019-04-24

668 Simple study designs in ecology produce inaccurate estimates of biodiversity responses

Christie, A. P.; Amano, T.; Martin, P. A.; Shackelford, G. E.; Simmons, B. I.; Sutherland, W. J.

10.1101/612101 — ecology — Posted on 2019-04-24

669 Differential Metabolic and Multi-tissue Transcriptomic Responses to Fructose Consumption among Genetically Diverse Mice

Zhang, G.; Byun, H. R.; Ying, Z.; Blencowe, M.; Zhao, Y.; Hong, J.; Shu, L.; Krishnan, K. C. K.; Gomez-Pinilla, F.; Yang, X.

10.1101/439562 — systems biology — Posted on 2019-04-24

670 Machine-Learning prognostic models from the 2014-16 Ebola outbreak: data-harmonization challenges, validation strategies, and mHealth applications

Colubri, A.; Hartley, M.-A.; Siakor, M.; Wolfman, V.; Sesay, T.; Felix, A.; Levine, A. C.; Sabeti, P. C.

10.1101/294587 — bioinformatics — Posted on 2019-04-24

671 Consistent alterations of human fecal microbes after transplanted to germ-free mice

Li, Y.; Cao, W.; Gao, N. L.; Zhao, X.-M.; Chen, W.-H.

10.1101/495663 — bioinformatics — Posted on 2019-04-24

672 Deep learning enables therapeutic antibody optimization in mammalian cells

Mason, D. M.; Friedensohn, S.; Weber, C. R.; Jordi, C.; Wagner, B.; Meng, S.; Reddy, S. T.

10.1101/617860 — synthetic biology — Posted on 2019-04-24

673 A novel uncultured marine cyanophage lineage with lysogenic potential linked to a putative marine Synechococcus ‘relic’ prophage

Flores-Uribe, J.; Philosof, A.; Sharon, I.; Fridman, S.; Larom, S.; Beja, O.

10.1101/325100 — microbiology — Posted on 2019-04-24

674 Realistic vOlumetric-Approach to Simulate Transcranial Electric Stimulation -- ROAST -- a fully automated open-source pipeline

Huang, Y.; Datta, A.; Bikson, M.; Parra, L. C.

10.1101/217331 — biophysics — Posted on 2019-04-24

675 Freshwater invasive clams grow faster and reproduce earlier in recently introduced populations with reduced growth rates

Hünicken, L. A.; Sylvester, F.; Bonel, N.

10.1101/618082 — ecology — Posted on 2019-04-24

676 From 3D to 3D: isolation of mesenchymal stem/stromal cells into a three-dimensional human platelet lysate matrix

Egger, D.; Oliveira, A. C.; Mallinger, B.; Hemeda, H.; Charwat, V.; Kasper, C.

10.1101/617738 — cell biology — Posted on 2019-04-24

677 Mutant p53 Drives Clonal Hematopoiesis through Modulating Epigenetic Pathway

Chen, S.; Wang, Q.; Yu, H.; Capitano, M. L.; Vemula, S.; Nabinger, S. C.; Gao, R.; Yao, C.; Kobayashi, M.; Geng, Z.; Fahey, A.; Henley, D.; Liu, S. Z.; Wolf, E. R.; Ramdas, B.; Cai, Z.; Gao, H.; Luo, N.; Sun, Y.; Wong, T. N.; Link, D. C.; Liu, Y.; Boswell, S. H.; Mayo, L. D.; Huang, G.; Kapur, R.; Yoder, M. C.; Broxmeyer, H. E.; Gao, Z.; Liu, Y.

10.1101/617779 — cancer biology — Posted on 2019-04-24

678 A single wave of monocytes is sufficient to replenish the long-term Langerhans cell network after immune injury

Ferrer, I. R.; West, H. C.; Henderson, S. L.; Ushakov, D. S.; Santos e Sousa, P. L.; Strid, J.; Chakraverty, R.; Yates, A. J.; Bennett, C. L.

10.1101/617514 — immunology — Posted on 2019-04-24

679 Single-Cell Analysis Reveals Regional Reprogramming during Adaptation to Massive Small Bowel Resection in Mice

Seiler, K. M.; Waye, S. E.; Kong, W.; Kamimoto, K.; Bajinting, A.; Goo, W. H.; Onufer, E. J.; Courtney, C.; Guo, J.; Warner, B. W.; Morris, S. A.

10.1101/615054 — genomics — Posted on 2019-04-24

680 DeepInterface: Protein-protein interface validation using 3D Convolutional Neural Networks

Balci, A. T.; Gumeli, C.; Hakouz, A.; Yuret, D.; Keskin, O.; Gursoy, A.

10.1101/617506 — bioinformatics — Posted on 2019-04-24

681 Metabolic control of YAP via the acto-myosin system during liver regeneration

Meyer, K.; Morales-Navarrete, H.; Seifert, S.; Wilsch-Braeuninger, M.; Dahmen, U.; Tanaka, E. M.; Brusch, L.; Kalaidzidis, Y.; Zerial, M.

10.1101/617878 — systems biology — Posted on 2019-04-24

682 Disrupted basal ganglia-thalamocortical loops in focal to bilateral tonic-clonic seizures

He, X.; Chaitanya, G.; Asma, B.; Bassett, D. S.; Tracy, J. I.; Sperling, M. R.

10.1101/618215 — neuroscience — Posted on 2019-04-24

683 The gut microbiota influences circulatory immune cell dynamics in humans

Schluter, J.; Peled, J. U.; Taylor, B. P.; Smith, M.; Taur, Y.; Morjaria, S.; Fenelus, M.; Pessin, M. S.; Hohl, T. M.; Perales, M.-A.; van den Brink, M. R. M.; Xavier, J. B.

10.1101/618256 — microbiology — Posted on 2019-04-24

684 The histone demethylase KDM5 controls developmental timing in Drosophila by promoting prothoracic gland endocycles.

Drelon, C.; Belalcazar, H. M.; Secombe, J.

10.1101/617985 — developmental biology — Posted on 2019-04-24

685 RNA transcribed from heterochromatic simple-tandem repeats are required for male fertility and histone-protamine exchange in Drosophila melanogaster

Mills, W. K.; Lee, Y. C. G.; Kochendoerfer, A. M.; Dunleavy, E. M.; Karpen, G. H.

10.1101/617175 — cell biology — Posted on 2019-04-24

686 Tracking the cells of tumor origin in breast organoids by light sheet microscopy

Alladin, A.; Chaible, L.; Reither, S.; Loeschinger, M.; Wachsmuth, M.; Heriche, J.-K.; Tischer, C.; Jechlinger, M.

10.1101/617837 — cancer biology — Posted on 2019-04-24

687 Structure-based validation can drastically under-estimate error rate in proteome-wide cross-linking mass spectrometry studies

Yugandhar, K.; Wang, T.-Y.; Yu, H.

10.1101/617654 — systems biology — Posted on 2019-04-24

688 Conditions for synaptic specificity during the maintenance phase of synaptic plasticity

Huertas, M.; Sacktor, T. C.; Shouval, H. Z.

10.1101/617928 — neuroscience — Posted on 2019-04-24

689 Evolution of Yin and Yang isoforms of a chromatin remodeling subunit results in the creation of two genes

Xu, W.; Long, L.; Zhao, Y.; Stevens, L.; Ellis, R. E.; McGrath, P. T.

10.1101/616995 — evolutionary biology — Posted on 2019-04-24

690 Single-molecule turnover dynamics of actin and membrane coat proteins in clathrin-mediated endocytosis

Lacy, M. M.; Baddeley, D.; Berro, J.

10.1101/617746 — cell biology — Posted on 2019-04-24

691 White matter microstructure and its relation to longitudinal measures of depressive symptoms in mid-late life

Shen, X.; Adams, M. J.; Ritakari, T. E.; Cox, S. R.; McIntosh, A. M.; Whalley, H. C.

10.1101/617530 — neuroscience — Posted on 2019-04-24

692 Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors

Saldivia, M.; Rao, S. P. S.; Fang, E.; Myburgh, E.; Brown, E.; Wollman, A. J. M.; Ritchie, R.; Lakhsminarayana, S. B.; Chen, Y. L.; Patra, D.; Koh, H. X.; Williams, S.; Supek, F.; Paape, D.; Bower-Lepts, C.; Leake, M. C.; McCulloch, R.; Kaiser, M.; Barrett, M. P.; Jiricek, J.; Diagana, T. T.; Mottram, J. C.

10.1101/616417 — microbiology — Posted on 2019-04-24

693 A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

Shen, X.; Howard, D. M.; Adams, M. J.; 23andMe Research Team, ; Major Depressive Disorder Working Group of the Psy, ; Deary, I. J.; McIntosh, A. M.; Whalley, H. C.

10.1101/617969 — genetics — Posted on 2019-04-24

694 Trophic plasticity of the highly invasive topmouth gudgeon (Pseudorasbora parva) inferred from stable isotope analysis

Rolla, M.; Consuegra, S.; Garcia de Leaniz, C.

10.1101/617688 — ecology — Posted on 2019-04-24

695 Inferring Protein Domain Semantic Roles Using word2vec

Buchan, D. W. A.; Jones, D. T.

10.1101/617647 — bioinformatics — Posted on 2019-04-24

696 Effect of PEI-coated MNPs on the Regulation of Cellular Focal Adhesions and Actin Stress Fibres

Narayanasamy, K. K.; Price, J. C.; Merkhan, M.; Elttayef, A.; Dobson, J.; Telling, N. D.

10.1101/617480 — bioengineering — Posted on 2019-04-24

697 Predictability of salient distractor increases top-down control in healthy younger and older adults

Haupt, M.; Napiorkowski, N.; Sorg, C.; Mueller, H. J.; Finke, K.

10.1101/617712 — neuroscience — Posted on 2019-04-24

698 Neighbor predation linked to natural competence fosters the transfer of large genomic regions in Vibrio cholerae

Matthey, N.; Stutzmann, S.; Stoudmann, C.; Guex, N.; Iseli, C.; Blokesch, M.

10.1101/618009 — microbiology — Posted on 2019-04-24

699 Real-time analysis of single influenza virus replication complexes reveals large promoter-dependent differences in initiation dynamics

Robb, N. C.; Kapanidis, A. N.; Fodor, E. C.; te Velthuis, A. J. W.

10.1101/617613 — microbiology — Posted on 2019-04-24

700 recount-brain: a curated repository of human brain RNA-seq datasets metadata

Razmara, A.; Ellis, S. E.; Sokolowski, D. J.; Davis, S.; Wilson, M. D.; Leek, J. T.; Jaffe, A. E.; Collado-Torres, L.

10.1101/618025 — genomics — Posted on 2019-04-24

701 Temperature preference does not evolve in sticklebacks despite multigenerational exposure to elevated temperatures

Pilakouta, N.; Killen, S. S.; Kristjansson, B. K.; Skulason, S.; Lindström, J.; Metcalfe, N. B.; Parsons, K.

10.1101/615005 — evolutionary biology — Posted on 2019-04-24

702 Genetic divergence outpaces phenotypic divergence among threespine stickleback populations in old freshwater habitats

Currey, M. C.; Bassham, S. L.; Cresko, W. A.

10.1101/618017 — evolutionary biology — Posted on 2019-04-24

703 Scalable method for groupwise comparisons and its application to chromatin accessibility among primates

Edsall, L. E.; Berrio, A.; Majoros, W. H.; Swain-Lenz, D.; Morrow, S.; Shibata, Y.; Safi, A.; Wray, G. A.; Crawford, G. E.; Allen, A. S.

10.1101/617951 — evolutionary biology — Posted on 2019-04-24

704 Cell fate determination by Lamarckian molecule-inheritance and chance

Bruggeman, F. J.; Schouten, J.; de Groot, D. H.; Planque, R.

10.1101/618199 — biophysics — Posted on 2019-04-24

705 Bactofilins form non-polar filaments that bind to membranes directly

Deng, X.; Gonzalez Llamazares, A.; Wagstaff, J. M.; Hale, V. L.; McLaughlin, S.; Cannone, G.; Kureisaite-Ciziene, D.; Löwe, J.

10.1101/617639 — biochemistry — Posted on 2019-04-24

706 ELIMAKI locus is required for mechanosensing and proprioception in birch trees

Alonso Serra, J.; Shi, X.; Peaucelle, A.; Rastas, P.; Bourdon, M.; Immanen, J.; Takahashi, J.; Koivula, H.; Eswaran, G.; Muranen, S.; Help-Rinta-Rahko, H.; Smolander, O.-P.; Su, C.; Safronov, O.; Gerber, L.; Salojarvi, J.; Hagqvist, R.; Mahonen, A.-P.; Nieminen, K.; Helariutta, Y.

10.1101/616474 — plant biology — Posted on 2019-04-24

707 An antisense oligonucleotide leads to suppressed transcriptional elongation of Hdac2 and long-term memory enhancement

Greer, C. B.; Poplawski, S.; Garbett, K. A.; McMahan, R. L.; Kordasiewicz, H. B.; Zhao, H.; Kennedy, A. J.; Goleva, S. B.; Sanders, T. H.; Motley, T.; Swayze, E. E.; Ecker, D. J.; Michael, T. P.; Sweatt, D.

10.1101/618116 — pharmacology and toxicology — Posted on 2019-04-24

708 Gene-specific methylation profiles for integrative methylation-expression analysis in cancer research

Liu, Y.; Baggerly, K. A.; Orouji, E.; Manyam, G.; Chen, H.; Lam, M.; Davis, J. S.; Lee, M. S.; Broom, B. M.; Menter, D. G.; Rai, K.; Kopetz, S.; Morris, J. S.

10.1101/618033 — genomics — Posted on 2019-04-24

709 STXBP5/tomosyn regulates both the small Rho GTPase and the surface expression of AMPA receptors to control the dendritic stability of neurons

Shen, W.; Kilander, M. B. C.; Bridi, M. S.; Frei, J. A.; Niescier, R. F.; Huang, S.; Lin, Y.-C.

10.1101/617845 — neuroscience — Posted on 2019-04-24

710 A Drosophila larval premotor/motor neuron connectome generating two behaviors via distinct spatio-temporal muscle activity

Arzan Zarin, A.; Mark, B.; Cardona, A.; Litwin-Kumar, A.; Doe, C. Q.

10.1101/617977 — neuroscience — Posted on 2019-04-24

711 The role of lineage, hemilineage and temporal identity in establishing neuronal targeting and connectivity in the Drosophila embryo

Mark, B.; Lai, S.-L.; Arzan Zarin, A.; Manning, L.; Cardona, A.; Truman, J. W.; Doe, C. Q.

10.1101/617936 — neuroscience — Posted on 2019-04-24

712 Information processing by endoplasmic reticulum stress sensors

Stroberg, W.; Eilertsen, J.; Schnell, S.

10.1101/617217 — systems biology — Posted on 2019-04-24

713 Rational programming of history-dependent logic in cellular populations.

Zuniga, A.; Guiziou, S.; Mayonove, P.; Ben Meriem, Z.; Camacho, M.; Moreau, V.; Ciandrini, L.; Hersen, P.; Bonnet, J.

10.1101/617209 — synthetic biology — Posted on 2019-04-24

714 A low cost, open source Turbidostat design for in-vivo control experiments in Synthetic Biology

Guarino, A.; Shannon, B.; Marucci, L.; Grierson, C.; Savery, N.; di Bernardo, M.

10.1101/617423 — synthetic biology — Posted on 2019-04-24

715 Best-compromise nutritional menus for childhood obesity

Bello, P.; Gallardo, P.; Pradenas, L.; Parada, V.

10.1101/618108 — scientific communication and education — Posted on 2019-04-24

716 Differences of endogenous polyamines and putative genes associated with paraquat resistance in goosegrass (Eleusine indica L.)

Luo, Q.; Wei, J.; Dong, Z.; Shen, X.; Chen, Y.

10.1101/618074 — plant biology — Posted on 2019-04-24

717 Natural Amelioration of Mn-induced Chlorosis Facilitated by Mn Down-regulation, Ammonium and Rainwater in Sugarcane Seedlings

Li, X. F.; Ling, G. Z.; Wang, X. X.; Yang, S.; Tang, X. L.; Jia, S. J.; Chang, M. M.

10.1101/618124 — plant biology — Posted on 2019-04-24

718 G-protein coupled receptor 88 knock-down in the associative striatum reduces the psychiatric symptoms in a translational model of Parkinson’s disease

Galet, B.; Ingallinesi, M.; Pegon, J.; Do Thi, A.; Ravassard, P.; Faucon Biguet, N.; Meloni, R.

10.1101/617456 — neuroscience — Posted on 2019-04-24

719 Brain endothelial cells are exquisite sensors of age-related circulatory cues

Chen, M. B.; Yousef, H.; Yang, A. C.; Lee, D.; Lehallier, B.; Schaum, N.; Quake, S. R.; Wyss-Coray, T.

10.1101/617258 — neuroscience — Posted on 2019-04-24

720 Intermanual transfer of visuomotor adaptation is related to awareness

Werner, S.; Strueder, H. K.; Donchin, O.

10.1101/617407 — neuroscience — Posted on 2019-04-24

721 A comprehensive characterization of rhythmic spiking activity in the rat ventral striatum

van der Meer, M.; Gmaz, J. M.; Carmichael, J. E.

10.1101/617233 — neuroscience — Posted on 2019-04-24

722 A neuroanatomically grounded optimal control model of the compensatory eye movement system

Holland, P. J.; Sibindi, T.; Ginzburg, M.; Das, S.; Arkesteijn, K.; Frens, M.; Donchin, O.

10.1101/617365 — neuroscience — Posted on 2019-04-24

723 Distinct Structural Features of the Lon Protease Drive Conserved Hand-over-Hand Substrate Translocation

Shin, M.; Asmita, A.; Puchades, C.; Adjei, E.; Wiseman, R. L.; Karzai, W.; Lander, G. C.

10.1101/617159 — molecular biology — Posted on 2019-04-24

724 SCAND1 suppresses CDC37 gene transcription by repressing MZF1

Eguchi, T.; Prince, T. L.; Tran, M. T.; Sogawa, C.; Lang, B. J.; Calderwood, S. K.

10.1101/617753 — molecular biology — Posted on 2019-04-24

725 The Vc2 cyclic di-GMP dependent riboswitch of Vibrio cholerae regulates expression of an upstream small RNA by controlling RNA stability

Pursley, B. R.; Waters, C. M.

10.1101/617340 — microbiology — Posted on 2019-04-24

726 Revisiting the regulation of the capsular polysaccharide biosynthesis gene cluster in Staphylococcus aureus

Keinhörster, D.; Salzer, A.; Duque, A.; George, S. E.; Marincola, G.; Lee, J. C.; Weidenmaier, C.; Wolz, C.

10.1101/614925 — microbiology — Posted on 2019-04-24

727 Interaction of Plasmodium falciparum Casein kinase 1 (PfCK1) with components of host cell protein trafficking machinery.

Batty, M. B.; Schittenhelm, R. B.; Doerig, C.; Garcia-Bustos, J.

10.1101/617571 — microbiology — Posted on 2019-04-24

728 A bifunctional ATPase drives tad pilus extension and retraction

Ellison, C. K.; Kan, J.; Chlebek, J. L.; Hummels, K. R.; Panis, G.; Viollier, P. H.; Biais, N.; Dalia, A. B.; Brun, Y.

10.1101/616128 — microbiology — Posted on 2019-04-24

729 Separation and detection of minimal length isomeric glycopeptide neoantigen epitopes centering GSTA region of MUC1 by LC-MS

Zhou, D.; Xiao, K.; TIan, Z.

10.1101/617308 — immunology — Posted on 2019-04-24

730 A secreted Echinococcus multilocularis activin A homologue promotes regulatory T cell expansion

Nono, J. K.; Lutz, M.; Brehm, K.

10.1101/618140 — immunology — Posted on 2019-04-24

731 NK cells force cytomegalovirus to use hematopoietic cells and immune evasion for dissemination after mucosal infection

Zhang, S.; Grey, F.; Snyder, C. M.

10.1101/618132 — immunology — Posted on 2019-04-24

732 Efficient use of genomic information for sustainable genetic improvement in small cattle populations

Obsteter, J.; Jenko, J.; Hickey, J. M.; Gorjanc, G.

10.1101/617464 — genomics — Posted on 2019-04-24

733 Neo-sex chromosomes and demography shape genetic diversity in the Critically Endangered Raso lark

Dierickx, E. G.; Sin, S. Y. W.; van Veelen, P.; Brooke, M. d. L.; Liu, Y.; Edwards, S. V.; Martin, S. H.

10.1101/617563 — genomics — Posted on 2019-04-24

734 Spodoptera frugiperda transcriptional response to infestation by Steinernema carpocapsae

Huot, L.; George, S.; Girard, P.-A.; Severac, D.; Negre, N.; Duvic, B.

10.1101/618165 — genomics — Posted on 2019-04-24

735 CrRLK1L receptor-like kinases HERCULES RECEPTOR KINASE 1 and ANJEA are female determinants of pollen tube reception

Galindo-Trigo, S.; Blanco-Tourinan, N.; DeFalco, T. A.; Wells, E. S.; Gray, J. E.; Zipfel, C.; Smith, L. M.

10.1101/428854 — genetics — Posted on 2019-04-24

736 Selection shapes synonymous stop codon use in mammals

Seoighe, C.; Kiniry, S. J.; Peters, A.; Baranov, P. V.; Yang, H.

10.1101/618157 — evolutionary biology — Posted on 2019-04-24

737 Infant sleep quality and its several related factors: An Indonesian samples

Wiguna, T.; Muskananfola, F.; Ismail, R. I.; Putri, T.; Chairunnisa, S.

10.1101/618058 — epidemiology — Posted on 2019-04-24

738 Nothing else matters? Tree diameter and living status have more effects than biogeoclimatic context on microhabitat number and occurrence: an analysis in French forest reserves.

Paillet, Y.; Debaive, N.; Archaux, F.; Cateau, E.; Gilg, O.; Guilbert, E.

10.1101/335836 — ecology — Posted on 2019-04-24

739 Nothing else matters? Tree diameter and living status have more effects than biogeoclimatic context on microhabitat number and occurrence: an analysis in French forest reserves.

Paillet, Y.; Debaive, N.; Archaux, F.; Cateau, E.; Gilg, O.; Guilbert, E.

10.1101/335836 — ecology — Posted on 2019-04-24

740 Nothing else matters? Tree diameter and living status have more effects than biogeoclimatic context on microhabitat number and occurrence: an analysis in French forest reserves.

Paillet, Y.; Debaive, N.; Archaux, F.; Cateau, E.; Gilg, O.; Guilbert, E.

10.1101/335836 — ecology — Posted on 2019-04-24

741 The influence of canopy radiation parameter uncertainty on model projections of terrestrial carbon and energy cycling

Viskari, T.; Shiklomanov, A.; Dietze, M.; Serbin, S.

10.1101/618066 — ecology — Posted on 2019-04-24

742 The knockout of the HMG-Domain of the porcine SRY-gene by CRISPR/Cas RNP microinjection causes sex reversal in gene-edited pigs

Kurtz, S.; Frenzel, A.; Lucas-Hahn, A.; Hassel, P.; Becker, R.; Ziegler, M.; Nowak-Imialek, M.; Schlegelberger, B.; Goehring, G.; Niemann, H.; Petersen, B.

10.1101/617589 — developmental biology — Posted on 2019-04-24

743 FOXP2 exhibits neuron class specific expression, but is not required for multiple aspects of cortical histogenesis

Kast, R. J.; Lanjewar, A. L.; Smith, C. D.; Levitt, P.

10.1101/617852 — developmental biology — Posted on 2019-04-24

744 An enhanced molecular tension sensor based on bioluminescence resonance energy transfer (BRET)

Gordon, W. R.; Aird, E. J.; Tompkins, K. J.

10.1101/617696 — cell biology — Posted on 2019-04-24

745 TMC1 confers a leak conductance to modulate excitability of auditory hair cells in mammals

Xiong, W.; Liu, S.; Wang, S.; Zou, L.; Li, J.; Song, C.; Chen, J.; Hu, Q.; Liu, L.

10.1101/617472 — cell biology — Posted on 2019-04-24

746 Lowe Syndrome-linked endocytic adaptors direct membrane cycling kinetics with OCRL in Dictyostelium discoideum.

Luscher, A.; Fröhlich, F.; Barisch, C.; Littlewood, C.; Metcalfe, J.; Leuba, F.; Palma, A.; Pirruccello, M.; Cesareni, G.; Stagi, M.; Walther, T. C.; Soldati, T.; De Camilli, P.; Swan, L. E.

10.1101/616664 — cell biology — Posted on 2019-04-24

747 LaNt α31 modulates LM332 organisation during matrix deposition leading to cell-matrix adhesion and migration defects.

Iorio, V.; Troughton, L. D.; Barrera, V.; Hamill, K.

10.1101/617597 — cell biology — Posted on 2019-04-24

748 The RhoGEF Cysts couples apical polarity proteins to Rho and myosin activity at adherens junctions

Silver, J. T.; Wirtz-Peitz, F.; Simoes, S.; Pellikka, M.; Yan, D.; Binari, R.; Nishimura, T.; Li, Y.; Harris, T. J.; Perrimon, N.; Tepass, U.

10.1101/617134 — cell biology — Posted on 2019-04-24

749 Consistent alterations of human fecal microbes after transplanted to germ-free mice

Li, Y.; Cao, W.; Gao, N. L.; Zhao, X.-M.; Chen, W.-H.

10.1101/495663 — bioinformatics — Posted on 2019-04-24

750 OrthoFinder: phylogenetic orthology inference for comparative genomics

Emms, D. M.; Kelly, S.

10.1101/466201 — bioinformatics — Posted on 2019-04-24

751 HAMAP rules as SPARQL - A portable annotation pipeline for genomes and proteomes

Bolleman, J.; de Castro, E.; Baratin, D.; Gehant, S.; Cuche, B. A.; Auchincloss, A.; COUDERT, E.; Hulo, C.; Masson, P.; Pedruzzi, I.; Rivoire, C.; Xenarios, I.; Redaschi, N.; Bridge, A.

10.1101/615294 — bioinformatics — Posted on 2019-04-24

752 LFMD: a new likelihood-based method to detect low-frequency mutations without molecular tags

Ye, R.; Ruan, J.; Zhuang, X.; Qi, Y.; An, Y.; Xu, J.; Mak, T.; Liu, X.; Yang, H.; Xu, X.; Baum, L.; Nie, C.; Sham, P. C.

10.1101/617381 — bioinformatics — Posted on 2019-04-24

753 Statistical modeling, estimation, and remediation of sample index hopping in multiplexed droplet-based single-cell RNA-seq data

Farouni, R.; Najafabadi, H. S.

10.1101/617225 — bioinformatics — Posted on 2019-04-24

754 A comprehensive computational study of amino acid interactions in membrane proteins

Mbaye, M. N.; Hou, Q.; Basu, S.; Teheux, F.; Pucci, F.; Rooman, M.

10.1101/617498 — bioinformatics — Posted on 2019-04-24

755 pH-responsive nano-vaccines as antigen and adjuvant carrier that improve vaccine immunogenicity

Smith, J.; Freeman, D.

10.1101/617324 — bioengineering — Posted on 2019-04-24

756 Post-translational modifications drive protein stability to control the dynamic beer brewing proteome

Kerr, E. D.; Caboche, C. H.; Schulz, B. L.

10.1101/358796 — biochemistry — Posted on 2019-04-24

757 Regulation of the 20S proteasome by a novel family of inhibitory proteins

Olshina, M. A.; Kumar-Deshmukh, F.; Arkind, G.; Fainer, I.; Taranavsky, M.; Hayat, D.; Ben-Dor, S.; Ben-Nissqan, G.; Sharon, M.

10.1101/617415 — biochemistry — Posted on 2019-04-24

758 Full-length de novo viral quasispecies assembly through variation graph construction

Baaijens, J.; van der Roest, B.; Koester, J.; Stougie, L.; Schoenhuth, A.

10.1101/287177 — bioinformatics — Posted on 2019-04-24

759 First report of New Clonal groups ST706 and ST1088 from MDR Klebsiella pneumoniae Mexican strains

Espinoza, M. G. C.; Arana, E. D. H.; GIONO-CEREZO, S.; ATANACIO, E. G. S.; TAPIA, E. C.; VAZQUEZ, L. I. C.; VAZQUEZ, R. G.

10.1101/616334 — microbiology — Posted on 2019-04-24

760 Feeling left out or just surprised? Neural correlates of social exclusion and over-inclusion in adolescence

Cheng, T. W.; Vijayakumar, N.; Flournoy, J. C.; Op de Macks, Z.; Peake, S. J.; Flannery, J. E.; Mobasser, A.; Alberti, S. L.; Fisher, P. A.; Pfeifer, J. H.

10.1101/524934 — neuroscience — Posted on 2019-04-24

761 Hydroxymethylated-P16 Allele Is Transcription-Inactive

Gan, Y.; Li, P.; Han, X.; Qin, S.; Cui, C.; Liu, Z.; Zhou, J.; Gu, L.; Lu, Z.; Zhang, B.; Deng, D.

10.1101/405522 — molecular biology — Posted on 2019-04-24

762 Using the basic reproduction number to assess the risk of transmission of lumpy skin disease virus by biting insects

Gubbins, S.

10.1101/602292 — epidemiology — Posted on 2019-04-24

763 Extreme midsummer rainfall event drives early onset cyanobacterial bloom

Larsen, M. L.; Baulch, H. M.; Schiff, S. L.; Simon, D. F.; Sauve, S.; Venkiteswaran, J. J.

10.1101/570275 — ecology — Posted on 2019-04-24

764 Multiplex Enrichment and Detection of Rare KRAS Mutations in Liquid Biopsy Samples using Digital Droplet Pre-Amplification

Pratt, E. D.; Cowan, R. W.; Manning, S. L.; Qiao, E.; Cameron, H.; Schradle, K.; Simeone, D. M.; Zhen, D. B.

10.1101/298299 — bioengineering — Posted on 2019-04-24

765 Characterization of Rhodopseudomonas palustris population dynamics on tobacco phyllosphere and induction of plant resistance to Tobacco mosaic virus i

Su, P.; Zhang, D.; Zhang, Z.; Chen, a.; Hamid, M. R.; Li, C.; Du, J.; Cheng, J.; Tan, X.; Zhen, L.; Zhai, Z.; Tang, W.; Chen, J.; Zhou, X.; Liu, Y.

10.1101/616110 — microbiology — Posted on 2019-04-23

766 Generalized locomotion of brittle stars with an arbitrary number of arms

Wakita, D.; Kagaya, K.; Aonuma, H.

10.1101/616383 — animal behavior and cognition — Posted on 2019-04-23

767 Cerebellar Modulation of Mesolimbic Dopamine Transmission is Functionally Asymmetrical

Holloway, Z. R.; Paige, N. B.; Comstock, J. F.; Nolen, H. G.; Sable, H. J.; Lester, D. B.

10.1101/615815 — neuroscience — Posted on 2019-04-23

768 β-lactamase Amplification and Porin Loss Drive Progressive β-lactam Resistance in Recurrent ESBL Enterobacteriaceae Bacteremia

Shropshire, W. C.; Aitken, S. L.; Pifer, R.; Kim, J.; Bhatti, M. M.; Li, X.; Kalia, A.; Galloway-Pena, J.; Sahasrabhojane, P.; Arias, C. A.; Greenberg, D. E.; Hanson, B. M.; Shelburne, S.

10.1101/616961 — genomics — Posted on 2019-04-23

769 Cancer control is a key functionality underlying evolution of extended lifespan in mammals

Kowalczyk, A.; Partha, R.; Clark, N.; Chikina, M.

10.1101/615914 — evolutionary biology — Posted on 2019-04-23

770 Quantifying the Payments for Ecosystem Services among hydrologic units in Zhujiang River Basin, China based on the indicator of Optional Capacity Value

Yang, H.; Zhao, B.; Chen, J.

10.1101/616680 — ecology — Posted on 2019-04-23

771 Zebrafish Gpr161 contributes to basal hedgehog repression in a tissue-specific manner

Tschaikner, P.; Regele, D.; Salvenmoser, W.; Geley, S.; Stefan, E.; Aanstad, P.

10.1101/616482 — cell biology — Posted on 2019-04-23

772 Analysis of the testis transcriptome of the Chagas’ disease vector Rhodnius prolixus

Cesar, J.; Ribeiro, J. M. C.; Pereira, M. H.; Araujo, R. N.; Gontijo, N. F.; Pessoa, G. C. D.; Sant'Anna, M. V.; Sorgine, M. H. F.; Majerowicz, D.; Medeiros, M.; Carvalho, A. B.; Braz, G.; Mesquita, R. D.; Oliveira, P. L.; Koerich, L. B.

10.1101/616193 — genomics — Posted on 2019-04-23

773 Adaptive Bet-Hedging Revisited: Considerations of Risk and Time Horizon

Tal, O.; Tran, T. D.

10.1101/617084 — evolutionary biology — Posted on 2019-04-23

774 Removing zero-lag functional connections can alter EEG source space networks at rest

Rizkallah, J.; Amoud, H.; Fraschini, M.; Wendling, F.; Hassan, M.

10.1101/617118 — neuroscience — Posted on 2019-04-23

775 Raw wastewater irrigation for urban agriculture in Africa increases the diversity of transferable antibiotic resistances genes in soil, including those encoding ESBLs

Bougnom, B.; Thiele-Bruhn, S.; Vito, R.; Zongo, C.; Piddock, L.

10.1101/615922 — microbiology — Posted on 2019-04-23

776 CCDC186 recruits EARP and controls dense-core vesicle cargo sorting by exit

Cattin-Ortola, J.; Topalidou, I.; Lau, H.-T.; Hummer, B.; Asensio, C. S.; Ong, S.-E.; Ailion, M.

10.1101/616458 — cell biology — Posted on 2019-04-23

777 PSC-RED, an Albumin-Free Robust Erythroid Differentiation Method to Produce Enucleated Red Blood Cells from Human Pluripotent Stem Cells

Olivier, E. E.; Zhang, S.; Yan, Z.; Suzuka, S.; Roberts, K. E.; Wang, K. E.; Bouhassira, E. E.

10.1101/616748 — bioengineering — Posted on 2019-04-23

778 Reconstructing the transcriptional ontogeny of maize and sorghum supports an inverse hourglass model of inflorescence development

Leiboff, S.; Hake, S.

10.1101/616235 — plant biology — Posted on 2019-04-23

779 Drug delivery to rodents: how to deal with body mass and water intake fluctuations?

Ferreira Goncalves, L.; Fernandes-Santos, C.

10.1101/615567 — pharmacology and toxicology — Posted on 2019-04-23

780 Split-Belt walking induces changes in active, but not passive, perception of step length

Sombric, C. J.; Gonzalez Rubio, M.; Torres-Oviedo, G.

10.1101/616631 — neuroscience — Posted on 2019-04-23

781 Beat-based and memory-based temporal expectations in rhythm: similar perceptual effects, different underlying mechanisms

Bouwer, F. L.; Honing, H.; Slagter, H. A.

10.1101/613398 — neuroscience — Posted on 2019-04-23

782 Genome annotation of Poly(lactic acid) degrading Pseudomonas aeruginosa and Sphingobacterium sp.

Satti, S. M.; Shah, A. A.; Auras, R.; Marsh, T.

10.1101/609883 — microbiology — Posted on 2019-04-23

783 An in vitro model maintaining taxon-specific functional activities of the gut microbiome

Li, L.; Abou-Samra, E.; Ning, Z.; Zhang, X.; Mayne, J.; Wang, J.; Cheng, K.; Walker, K.; Stintzi, A.; Figeys, D.

10.1101/616656 — microbiology — Posted on 2019-04-23

784 The splicing factor hnRNP M is a critical regulator of innate immune gene expression in macrophages

West, K. O.; Scott, H. M.; Torres-Odio, S.; West, A. P.; Patrick, K.; Watson, R. O.

10.1101/617043 — immunology — Posted on 2019-04-23

785 coMethDMR: Accurate identification of co-methylated and differentially methylated regions in epigenome-wide association studies

Gomez, L.; Odom, G.; Young, J.; Martin, E.; Liu, L.; Chen, X.; Griswold, A.; Gao, Z.; Zhang, L.; Wang, L.

10.1101/615427 — bioinformatics — Posted on 2019-04-23

786 Graph-Based Method for Anomaly Detection in Functional Brain Network using Variational Autoencoder

mirakhorli, j.; mirakhorli, m.

10.1101/616367 — bioinformatics — Posted on 2019-04-23

787 A qualitative study exploring researchers’ perspectives on authorship decision-making

Maggio, L. A.; Artino, A. R.; Watling, C. J.; Driessen, E. W.; O'Brien, B. C.

10.1101/615112 — scientific communication and education — Posted on 2019-04-23

788 Neurostructural Heterogeneity in Youth with Internalizing Symptoms

Kaczkurkin, A. N.; Sotiras, A.; Baller, E. B.; Calkins, M. E.; Chand, G. B.; Cui, Z.; Erus, G.; Fan, Y.; Gur, R. E.; Gur, R. C.; Moore, T. M.; Roalf, D. R.; Rosen, A. F. G.; Ruparel, K.; Shinohara, R. T.; Varol, E.; Wolf, D. H.; Davatzikos, C.; Satterthwaite, T. D.

10.1101/614438 — neuroscience — Posted on 2019-04-23

789 Effects of compassion training on brain responses to suffering others

Ashar, Y.; ANDREWS-HANNA, J.; Halifax, J.; DIMIDJIAN, S.; WAGER, T.

10.1101/616029 — neuroscience — Posted on 2019-04-23

790 A rapid and accurate MinION-based workflow for tracking species biodiversity in the field

Maestri, S.; Cosentino, E.; Paterno, M.; Freitag, H.; Garces, J. M.; Marcolungo, L.; Alfano, M.; Njunjic, I.; Schilthuizen, M.; Slik, F.; Menegon, M.; Rossato, M.; Delledonne, M.

10.1101/617019 — genomics — Posted on 2019-04-23

791 Simple study designs in ecology produce inaccurate estimates of biodiversity responses

Christie, A. P.; Amano, T.; Martin, P. A.; Shackelford, G. E.; Simmons, B. I.; Sutherland, W. J.

10.1101/612101 — ecology — Posted on 2019-04-23

792 Huntingtin confers fitness but is not embryonically essential in zebrafish development

Pouladi, M. A.; Sidik, H.; Ang, C. J.

10.1101/615591 — developmental biology — Posted on 2019-04-23

793 Molecular mapping of transmembrane mechanotransduction through the β1 integrin-CD98hc-TRPV4 axis

Potla, R.; Mariko Hirano-Kobayashi, M.; Wu, H.; Chen, H.; Mammoto, A.; Matthews, B. D.; Ingber, D. E.

10.1101/617092 — cell biology — Posted on 2019-04-23

794 Three-dimensional Monolayer Stress Microscopy

Serrano, R.; Aung, A.; Yeh, Y.-T.; Varghese, S.; Lasheras, J. C.; del Alamo, J. C.

10.1101/616987 — biophysics — Posted on 2019-04-23

795 The MADS-box transcription factor PHERES1 controls imprinting in the endosperm by binding to domesticated transposons

A. Batista, R.; Moreno-Romero, J.; van Boven, J.; Qiu, Y.; Santos-Gonzalez, J.; D. Figueiredo, D.; Kohler, C.

10.1101/616698 — plant biology — Posted on 2019-04-23

796 cT-DNA in Linaria vulgaris L. is multicopy, inverted and homogenized.

Vladimirov, I.; Pavlova, O.; Polev, D.; Bogomaz, D.

10.1101/615328 — plant biology — Posted on 2019-04-23

797 Cognitive modeling informs interpretation of go/no-go task-related neural activations and their links to externalizing psychopathology

Weigard, A.; Soules, M.; Ferris, B.; Zucker, R.; Sripada, C.; Heitzeg, M.

10.1101/614420 — neuroscience — Posted on 2019-04-23

798 All-optical electrophysiology reveals excitation, inhibition, and neuromodulation in cortical layer 1

Fan, L. Z.; Kheifets, S.; Boehm, U. L.; Piatkevich, K. D.; Wu, H.; Parot, V.; Xie, M.; Boyden, E. S.; Takesian, A. E.; Cohen, A. E.

10.1101/614172 — neuroscience — Posted on 2019-04-23

799 ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells

Rodriguez, A. C.; Vahrenkamp, J. M.; Berrett, K. C.; Clark, K. A.; Guillen, K. P.; Scherer, S. D.; Yang, C.-H.; Welm, B. E.; Janat-Amsbury, M. M.; Graves, B. J.; Gertz, J.

10.1101/617142 — molecular biology — Posted on 2019-04-23

800 Combining multiple data sources in species distribution models while accounting for spatial dependence and overfitting with combined penalised likelihood maximisation

Renner, I.; Louvrier, J.; Gimenez, O.

10.1101/615583 — ecology — Posted on 2019-04-23

801 Mapping cell migrations and fates from a gastruloid model to the human primitive streak

Martyn, I.; Siggia, E.; Brivanlou, A.

10.1101/616227 — developmental biology — Posted on 2019-04-23

802 Angiocrine FSTL1 insufficiency leads to atrial and vein wall fibrosis via SMAD3 activation

Jiang, H.; Zhang, L.; Liu, X.; Sun, W.; Kato, K.; Chen, C.; Li, X.; Han, W.; Zhang, F.; Xiao, Q.; Yang, Z.; Qin, Z.; Adams, R. H.; Gao, X.; He, Y.

10.1101/616623 — developmental biology — Posted on 2019-04-23

803 Carry-over effects of temperature and pCO2 in multiple Olympia oyster populations

Spencer, L. H.; Venkataraman, Y. R.; Crim, R.; Ryan, S.; Horwith, M. J.; Roberts, S. B.

10.1101/616375 — physiology — Posted on 2019-04-23

804 Re-weighting of Sound Localization Cues by Audiovisual Training

Kumpik, D. P.; Campbell, C.; Schnupp, J.; King, A. J.

10.1101/616490 — neuroscience — Posted on 2019-04-23

805 Probing dynamical cortical gating of attention with concurrent TMS-EEG

Okazaki, Y. O.; Mizuno, Y.; Kitajo, K.

10.1101/615708 — neuroscience — Posted on 2019-04-23

806 The identification of temporal communities through trajectory clustering correlates with single-trial behavioural fluctuations in neuroimaging data

Thompson, W. H.; Wright, J.; Shine, J. M.; Poldrack, R. A.

10.1101/617027 — neuroscience — Posted on 2019-04-23

807 A tetRA-based promoter system for the generation of conditional knockouts in Campylobacter jejuni

Cohen, E. J.; Quek, R. T.; Beeby, M.

10.1101/616649 — microbiology — Posted on 2019-04-23

808 TCR repertoire analysis reveals effector memory T cells differentiation into Th17 cells in rheumatoid arthritis

Jiang, X.; Wang, S.-y.; Zhou, C.; Wu, J.-h.; Jiao, Y.-h.; Lin, L.-y.; Lu, X.; Yang, B.; Zhang, W.; Xiao, X.-y.; Li, Y.-t.; Wu, X.-y.; Wang, X.; Chen, H.; Zhao, L.-d.; Fei, Y.-y.; Yang, H.-x.; Zhang, W.; Zhang, F.-c.; Chen, H.; Zhang, J.-m.; Li, B.; Yang, H.-m.; Wang, J.; He, W.; Cao, X.-t.; Liu, D.-p.; Liu, X.; Zhang, X.

10.1101/616441 — immunology — Posted on 2019-04-23

809 Genetic analysis of the transition from wild to domesticated cotton (G. hirsutum)

Grover, C. E.; Yoo, M.-J.; Gore, M. A.; Harker, D. B.; Byers, R. L.; Lipka, A. E.; Hu, G.; Yuan, D.; Conover, J.; Udall, J. A.; Paterson, A. H.; Wendel, J.

10.1101/616763 — genetics — Posted on 2019-04-23

810 How heterozygote advantage can promote the evolution of disassortative mating and shape the underlying geneticarchitecture?

Maisonneuve, L.; Chouteau, M.; Joron, M.; Llaurens, V.

10.1101/616409 — evolutionary biology — Posted on 2019-04-23

811 Increasing growth rate slows adaptation when genotypes compete for diffusing resources

Chacon, J. M.; Harcombe, W. R.

10.1101/616938 — evolutionary biology — Posted on 2019-04-23

812 Inter- and intra-specific variation of spider mite susceptibility to fungal infections: implications for the long-term success of biological control

Zele, F.; Altintas, M.; Lopes dos Santos, I. F.; Cakmak, I.; Magalhaes, S.

10.1101/615344 — ecology — Posted on 2019-04-23

813 Human biting Culex pipiens bioform molestus is spread in several areas in south Sweden.

Luande, V. N.; Eklof, D.; Lindstrom, A.; Nyanjom, S.; Evander, M.; Lilja, T.

10.1101/616706 — ecology — Posted on 2019-04-23

814 ABioTrans: A Biostatistical tool for Transcriptomics Analysis

Yutong, Z.; Thuy Tien, B.; Selvarajoo, K.

10.1101/616300 — bioinformatics — Posted on 2019-04-23

815 Disentangling unity from diversity in developmental psychopathology

MENDES, L.; Polanczyk, G.; Rohde, L. A.; Salum, G.

10.1101/616177 — animal behavior and cognition — Posted on 2019-04-23

816 Explicit control of step timing during split-beltwalking reveals interdependent recalibrationof movements in space and time

Gonzalez-Rubio, M.; Velasquez, N. F.; Torres-Oviedo, G.

10.1101/614644 — neuroscience — Posted on 2019-04-23

817 Decreased viability and neurite length in neural cells treated with chitosan-dextran sulfate nanocomplexes

zamproni, l.; Teixira, D.; Alliegro, A. A.; Maugeri, I. L.; des Rieux, A.; Porcionatto, M.

10.1101/616144 — neuroscience — Posted on 2019-04-23

818 Population imaging of neural activity in awake behaving mice in multiple brain regions

Piatkevich, K. D.; Bensussen, S.; Tseng, H.-a.; Shroff, S. N.; Lopez-Huerta, V. G.; Park, D.; Jung, E. E.; Shemesh, O. A.; Straub, C.; Gritton, H. J.; Romano, M. F.; Costa, E.; Sabatini, B. L.; Fu, Z.; Boyden, E. S.; Han, X.

10.1101/616094 — neuroscience — Posted on 2019-04-23

819 Estrogen accelerates heart regeneration by promoting inflammatory responses in zebrafish

Shisan, X.; Fangjing, X.; Samane, F.; Fariba, B.; Lina, Z.; Kin Fung, W.; Yinmin, L.; Rajkumar, R.; Lei, S.; Xin, W.; Yun Wah, L.; Shuk Han, C.

10.1101/616250 — developmental biology — Posted on 2019-04-23

820 MicroED with the Falcon III direct electron detector

Hattne, J.; Martynowycz, M. W.; Gonen, T.

10.1101/615484 — biochemistry — Posted on 2019-04-23

821 Plant-Necrotroph Co-transcriptome Networks Illuminate a Metabolic Battlefield

Zhang, W.; Corwin, J. A.; Copeland, D.; Feusier, J.; Eshbaugh, R.; Cook, D. E.; Atwell, S.; Kliebenstein, D. J.

10.1101/485235 — systems biology — Posted on 2019-04-23

822 G2M splits mouse embryonic stem cells into naïve and formative pluripotency states

Jaager, K.; Simpson, D.; Kalantzaki, M.; Salzano, A.; Chambers, I.; Chandra, T.

10.1101/616516 — developmental biology — Posted on 2019-04-23

823 Synthesizing Disparate LiDAR and Satellite Datasets through Deep Learning to Generate Wall-to-Wall Regional Forest Inventories

Ayrey, E.; Hayes, D. J.; Kilbride, J. B.; Weiskittel, A. R.

10.1101/580514 — ecology — Posted on 2019-04-23

824 Quantitative proteomics identifies novel PIAS1 protein substrates involved in cell migration and motility

Li, C.; McManus, F. P.; Plutoni, C.; Pascariu, C. M.; Nelson, T.; Alberici Delsin, L. E.; Emery, G.; Thibault, P.

10.1101/612622 — cancer biology — Posted on 2019-04-23

825 Machine Source Localization of Tursiops Truncatus Whistle-like Sounds in a Reverberant Aquatic Environment

Woodward, S. F.; Reiss, D.; Magnasco, M.

10.1101/606673 — biophysics — Posted on 2019-04-23

826 Frequency dependent responses of neuronal models to oscillatory inputs in current versus voltage clamp

Rotstein, H. G.; Nadim, F.

10.1101/515510 — neuroscience — Posted on 2019-04-23

827 Rapid growth and defence evolution following multiple introductions

van Boheemen, L. A.; Bou-Assi, S.; Uesugi, A.; Hodgins, K. A.

10.1101/435271 — evolutionary biology — Posted on 2019-04-23

828 Single-Cell Transcriptomic Evidence for Dense Intracortical Neuropeptide Networks

Smith, S. J.; Sumbul, U.; Graybuck, L. T.; Collman, F.; Seshamani, S.; Gala, R.; Gliko, O.; Elabbady, L.; Miller, J.; Bakken, T.; Rossier, J.; Yao, Z.; Lein, E.; Zeng, H.; Tasic, B.; Hawrylycz, M.

10.1101/519694 — neuroscience — Posted on 2019-04-23

829 Enhancers facilitate the birth of de novo genes and their functional integration into regulatory networks

Majic, P.; Payne, J.

10.1101/616581 — evolutionary biology — Posted on 2019-04-23

830 Sphingomyelin is critical in organizing phosphoinositide dynamics during phagocytic uptake of Mycobacterium tuberculosis.

Niekamp, P.; Guzman, G.; Leier, H.; Rashidfarrokhi, A.; Richina, V.; Holthuis, J.; Tafesse, F. G.

10.1101/565226 — microbiology — Posted on 2019-04-23

831 Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis

Schafflick, D.; Xu Antelope, C.; Hartlehnert, M.; Cole, M.; Lautwein, T.; Schulte-Mecklenbeck, A.; Wolbert, J.; Heming, M. O.; Meuth, S. G.; Kuhlmann, T.; Gross, C. C.; Wiendl, H.; Yosef, N.; Meyer zu Horste, G.

10.1101/403527 — immunology — Posted on 2019-04-23

832 Whole genome bisulfite sequencing of Down syndrome brain reveals regional DNA hypermethylation and novel disease insights

Laufer, B. I.; Hwang, H.; Vogel Ciernia, A.; Mordaunt, C. E.; LaSalle, J. M.

10.1101/428482 — genomics — Posted on 2019-04-23

833 EternaBrain: Automated RNA design through move sets and strategies from an Internet-scale RNA videogame

Koodli, R.; Keep, B.; Coppess, K. R.; Portela, F.; Eterna Players, ; Das, R.

10.1101/326736 — bioinformatics — Posted on 2019-04-23

834 Neuronal aging potentiates beta-amyloid generation via amyloid precursor protein endocytosis

Burrinha, T.; Gomes, R.; Terrasso, A.; Almeida, C.

10.1101/616540 — neuroscience — Posted on 2019-04-23

835 DRPnet - Automated Particle Picking In Cryo-Electron Micrographs Using Deep Regression

Nguyen, N. P.; Ersoy, I.; Gotberg, J.; Bunyak, F.; White, T. A.

10.1101/616169 — molecular biology — Posted on 2019-04-23

836 Genetic risk loadings influence the susceptibility and severity of systemic lupus erythematosus

Chen, L.; Tombleson, P.; Bielowka, A.; Odhams, C. A.; Roberts, A. L.; Cunninghame Graham, D. S.; Vyse, T. J.; Morris, D. L.

10.1101/614867 — genetics — Posted on 2019-04-23

837 Methylation content sensitive enzyme ddRAD (MCSeEd): a reference-free, whole genome profiling system to address cytosine/ adenine methylation changes

Marconi, G.; Capomaccio, S.; Comino, C.; Acquadro, A.; Portis, E.; Porceddu, A.; Albertini, E.

10.1101/616532 — genomics — Posted on 2019-04-23

838 Quantitative proteomics identifies novel PIAS1 protein substrates involved in cell migration and motility

Li, C.; McManus, F. P.; Plutoni, C.; Pascariu, C. M.; Nelson, T.; Emery, G.; Thibault, P.

10.1101/612622 — cancer biology — Posted on 2019-04-23

839 Electrospinning of pure, native, cross-linker free self-supported collagen membrane

Dems, D.; Rodrigues Da Silva, J.; Helary, C.; Wien, F.; Schanne-Klein, M.-C.; Laberty-Robert, C.; Krins, N.; Aime, C.

10.1101/616946 — bioengineering — Posted on 2019-04-23

840 Distinct changes in morphometric networks in aging versus Alzheimer’s disease dementia

10.1101/615401 — neuroscience — Posted on 2019-04-23

841 The histidine kinase PdtaS is a cyclic di-GMP binding metabolic sensor that controls mycobacterial adaptation to nutrient deprivation

Hariharan, V. N.; Thakur, C.; Singh, A.; Gopinathan, R.; Singh, D. P.; Sankhe, G.; Chandran, N.; Bhatt, A.; Saini, D. K.

10.1101/615575 — microbiology — Posted on 2019-04-23

842 Vitamin D deficiency during pregnancy and its associated factors among third trimester Malaysian pregnant women

Woon, F. C.; Chin, Y. S.; Ismail, I. H.; Batterham, M.; Abdul Latiff, A. H.; Gan, W. Y.; Appannah, G.; Mohammed Hussien, S. H.; Edi, M.; Tan, M. L.; Chan, Y. M.

10.1101/616805 — epidemiology — Posted on 2019-04-23

843 Basal Ganglia role in learning rewarded actions and executing previously learned choices: healthy and diseased states

Mulcahy, G.; Atwood, B.; Kuznetsov, A.

10.1101/616854 — neuroscience — Posted on 2019-04-23

844 Proximity Labeling to Map Host-Pathogen Interactions at the Membrane of a Bacteria Containing Vacuole in Chlamydia trachomatis Infected Human Cells

Olson, M. G.; Widner, R. E.; Jorgenson, L. M.; Lawrence, A.; Lagundzin, D.; Woods, N. T.; Ouellette, S. P.; Rucks, E. A.

10.1101/616896 — microbiology — Posted on 2019-04-23

845 An alanine permease mutation or exposure to D-cycloserine re-sensitizes MRSA to beta-lactam antibiotics

Gallagher, L.; Shears, R. K.; Fingleton, C.; Alvarez, L.; Waters, E.; Clarke, J.; Bricio-Moreno, L.; Campbell, C.; Yadav, A.; Razvi, F.; O'Neill, E.; O'Neill, A.; Cava, F.; Fey, P.; Kadioglu, A.; O'Gara, J. P.

10.1101/616920 — microbiology — Posted on 2019-04-23

846 Comparison of National Level Spatial and Spatio-temporal Models of Malaria

Toh, K. B.; Valle, D.

10.1101/616847 — epidemiology — Posted on 2019-04-23

847 The effects of a TMS double lesion to a cortical network

Cameron, I.; Cretu, A.; Struik, F.; Toni, I.

10.1101/517128 — neuroscience — Posted on 2019-04-23

848 Small RNA Mcr11 regulates genes involved in the central metabolism of Mycobacterium tuberculosis and requires 3 sequence along with the transcription factor AbmR for stable expression

Girardin, R. C.; McDonough, K.

10.1101/616912 — microbiology — Posted on 2019-04-23

849 A dispensable paralog of succinate dehydrogenase subunit C mediates standing resistance towards a subclass of SDHI fungicides in Zymoseptoria tritici

Steinhauer, D.; Salat, M.; Frey, R.; Mosbach, A.; Luksch, T.; Balmer, D.; Hansen, R.; Widdison, S.; Logan, G.; Dietrich, R. A.; Kema, G. H.; Bieri, S.; Sierotzki, H.; Torriani, S. F.; Scalliet, G.

10.1101/616904 — microbiology — Posted on 2019-04-23

850 Smear positive tuberculosis and genetic diversity of M. tuberculosis isolates in individuals visiting health facilities in South Gondar Zone, northwest Ethiopia

Alelign, A.; Petros, B.; Ameni, G.

10.1101/616789 — epidemiology — Posted on 2019-04-23

851 PanoView: An iterative clustering for single-cell RNA sequencing data

Hu, M.-W.; Kim, D. W.; Liu, S.; Zack, D.; Blackshaw, S.; Qian, J.

10.1101/616862 — bioinformatics — Posted on 2019-04-23

852 Prevalence and Determinants of Caesarean Section in South and South-east Asian Women

Vishwakarma, R.; Verma, V.; Nath, D. C.; Prakash, R.; Abid, O.

10.1101/616813 — scientific communication and education — Posted on 2019-04-23

853 Targeted transcript quantification in single disseminated cancer cells after whole transcriptome amplification

Durst, F. C.; Grujovic, A.; Ganser, I.; Hoffmann, M.; Ugocsai, P.; Klein, C. A.; Czyz, Z. T.

10.1101/616839 — molecular biology — Posted on 2019-04-23

854 Horizontal transmission of the entomopathogenic fungal isolate INRS-242 of Beauveria bassiana in emerald ash borer, Agrilus planipennis Fairmaire

Srei, N.; Lavallee, R.; Guertin, C.

10.1101/532838 — microbiology — Posted on 2019-04-23

855 Type I interferon-dependent CCL4 is induced by a cGAS/STING pathway that bypasses viral inhibition and protects infected tissue, independent of viral burden

Parekh, N. J.; Krouse, T. E.; Reider, I. E.; Hobbs, R. P.; Ward, B. M.; Norbury, C. C.

10.1101/616888 — immunology — Posted on 2019-04-23

856 Single-cell DNA and RNA sequencing reveals the dynamics of intra-tumor heterogeneity in a colorectal cancer model

Ono, H.; Arai, Y.; Furukawa, E.; Narushima, D.; Matsuura, T.; Nakamura, H.; Shiokawa, D.; Nagai, M.; Imai, T.; Mimori, K.; Okamoto, K.; Hippo, Y.; Shibata, T.; Kato, M.

10.1101/616870 — genomics — Posted on 2019-04-23

857 Evolutionary Transitions in Heritability and Individuality

Bourrat, P.

10.1101/192443 — evolutionary biology — Posted on 2019-04-23

858 Monitoring soil microorganisms with community-level physiological profiles using Biolog EcoPlatesTM in Chaohu lakeside wetland, east China

Teng, Z.; Fan, W.; Wang, H.; Cao, X.; Xu, X.

10.1101/616821 — ecology — Posted on 2019-04-23

859 Identification of Host Biomarkers of EBV Latency IIb and Latency III

Messinger, J. E.; Dai, J.; Stanland, L. J.; Price, A. M.; Luftig, M. A.

10.1101/616359 — cancer biology — Posted on 2019-04-23

860 A Cys2/His2 zinc finger protein acts as a repressor of gibberellins biosynthesis by regulating SD1/OsGA20ox2 in rice (Oryza sativa L.)

Duan, M.; Ke, X.; Lan, H.; Yuan, X.; Huang, P.; Xu, E.; Gao, X.; Wang, R.; Tang, H.; Zhang, H.; Huang, J.

10.1101/616433 — molecular biology — Posted on 2019-04-23

861 Invasive species-driven trophic cascades: Are cane toads indirectly contributing to small mammal collapses across tropical Australia?

Radford, I. J.; Woolley, L.-A.; Dickman, C. R.; Corey, B.; Trembath, D.; Fairman, R.

10.1101/616771 — ecology — Posted on 2019-04-23

862 Rapid and highly sensitive detection of pyocyanin biomarker in different Pseudomonas aeruginosa infections using gold nanoparticles modified sensor

Elkhawaga, A. A.; Khalifa, M. M.; El-badawy, O. H. B.; Hassan, M. A.; El-Said, W. A.

10.1101/616797 — biochemistry — Posted on 2019-04-23

863 Fast and cloning-free CRISPR/Cas9-mediated genomic editing in mammalian cells

Manna, P. T.; Davis, L. J.; Robinson, M. S.

10.1101/612192 — molecular biology — Posted on 2019-04-23

864 Animal, fungi, and plant genome sequences harbour different non-canonical splice sites

Frey, K.; Pucker, B.

10.1101/616565 — genomics — Posted on 2019-04-23

865 Growth hormone induces TGF-β1 in glomerular podocytes: Implications in podocytopathy and proteinuria

Pasupulati, A. k.; Mukhi, D.; NISHAD, R.; Singh, A. K.

10.1101/597344 — cell biology — Posted on 2019-04-23

866 Perception of aversive stimuli of different gustatory modalities in an haematophagous insect, Rhodnius prolixus.

Masague, S.; Cano, A.; Asparch, Y.; Barrozo, R. B.; Minoli, S.

10.1101/616615 — animal behavior and cognition — Posted on 2019-04-23

867 Metabolic Perceptrons for Neural Computing in Biological Systems

Pandi, A.; Koch, M.; Voyvodic, P. L.; Soudier, P.; Bonnet, J.; Kushwaha, M.; Faulon, J.-L.

10.1101/616599 — synthetic biology — Posted on 2019-04-23

868 The inhibition of automatic imitation: a meta-analysis and synthesis of fMRI studies

Darda, K. M.; Ramsey, R.

10.1101/334938 — neuroscience — Posted on 2019-04-23

869 PSX: Protein-Solvent Exchange - Software for calculation of deuterium-exchange effects in SANS measurements from protein coordinates

Pedersen, M. C.; Wang, Y.; Tidemand, F. G.; Martel, A.; Lindorff-Larsen, K.; Arleth, L.

10.1101/609859 — biophysics — Posted on 2019-04-23

870 Zinc restriction promotes β-cell hyper-hormonemia and endocrine pancreas degeneration in mice

Sisnande, T.; Lima, C. K.; Da Silva, D. C.; Beninatto, T. M.; Alves, N. L.; Amaral, M. J.; Miranda-Alves, L.; Lima, L. M. T.

10.1101/616201 — biochemistry — Posted on 2019-04-23

871 Dorsal and ventral hippocampus engage opposing networks in the nucleus accumbens

Sosa, M.; Joo, H. R.; Frank, L. M.

10.1101/604116 — neuroscience — Posted on 2019-04-23

872 Cell-type and endocannabinoid specific synapse connectivity in the adult nucleus accumbens core

Deroche, M. A.; Lassalle, O.; Manzoni, O. J.

10.1101/613497 — neuroscience — Posted on 2019-04-23

873 Cognitive modulation of interacting corollary discharges in the visual cortex

Abdolrahmani, M.; Lyamzin, D. R.; Aoki, R.; Benucci, A.

10.1101/615229 — neuroscience — Posted on 2019-04-23

874 Behavioural analysis of single-cell aneural ciliate, Stentor roeselii, using machine learning approaches

Trinh, K. M.; Wayland, M.; Prabakaran, S.

10.1101/594796 — animal behavior and cognition — Posted on 2019-04-23

875 RAxML-NG: A fast, scalable, and user-friendly tool for maximum likelihood phylogenetic inference

Kozlov, A.; Darriba, D.; Flouri, T.; Morel, B.; Stamatakis, A.

10.1101/447110 — bioinformatics — Posted on 2019-04-23

876 Effects of bicycle geometry and riding position on the potential of residual limb muscles to pedaling with a transfemoral prosthesis: a computer simulation study

Okita, Y.; Nakamura, T.

10.1101/615245 — bioengineering — Posted on 2019-04-23

877 A comparison between power spectral density and network metrics: an EEG study

Demuru, M.; La Cava, S. M.; Pani, S. M.; Fraschini, M.

10.1101/614271 — bioengineering — Posted on 2019-04-23

878 Degraded auditory and visual speech affects theta synchronization and alpha power differently

Hauswald, A.; Keitel, A.; Roesch, S.; Weisz, N.

10.1101/615302 — neuroscience — Posted on 2019-04-23

879 Resistance to aztreonam, in combination with a bicyclic boronate β-lactamase inhibitor in Escherichia coli identified following mixed culture selection

Cheung, C. H. P.; Findlay, J.; Heesom, K. J.; Avison, M.

10.1101/615336 — microbiology — Posted on 2019-04-23

880 Preparation of PLGA Nanoparticles Encapsulated with Fluorescent Probe Coumarin-6

Smith, J.; Purr, E.

10.1101/614875 — bioengineering — Posted on 2019-04-23

881 Inter-individual and inter-strain differences in cognitive and social abilities of Dark Agouti and Wistar Han rats

Alonso, L.; Peeva, P.; Ramos-Prats, A.; Alenina, N.; Winter, Y.; Rivalan, M.

10.1101/566877 — animal behavior and cognition — Posted on 2019-04-23

882 The BvgS PAS domain: an independent sensory perception module in the Bordetella BvgAS phosphorelay

Cotter, P. A.; Sobran, M. A.

10.1101/614891 — microbiology — Posted on 2019-04-23

883 CNNcon: A Quantitative Imaging Tool for Lung CT Image Feature Analysis

Causey, J.; Qualls, J.; Moore, J. H.; Prior, F.; Huang, X.

10.1101/615492 — bioinformatics — Posted on 2019-04-23

884 DeepGOPlus: Improved protein function prediction from sequence

Kulmanov, M.; Hoehndorf, R.

10.1101/615260 — bioinformatics — Posted on 2019-04-23

885 Germline genomic patterns are associated with cancer risk, oncogenic pathways and clinical outcomes

Feng, X.; Xu, X.; Li, D.; Cui, Q.; Wang, E.

10.1101/616268 — cancer biology — Posted on 2019-04-23

886 Can fallopian tube anatomy predict pregnancy and pregnancy outcomes after tubal reversal surgery?

S. de Souza, R.; S. Berger, G.

10.1101/616508 — bioinformatics — Posted on 2019-04-23

887 Individual structural features constrain the functional connectome

Melozzi, F.; Bergmann, E.; Harris, J. A.; Kahn, I.; Jirsa, V.; Bernard, C.

10.1101/613307 — neuroscience — Posted on 2019-04-23

888 An encoding of genome content for machine learning

Viehweger, A.; Krautwurst, S.; Parks, D. H.; Koenig, B.; Marz, M.

10.1101/524280 — genomics — Posted on 2019-04-23

889 Factors associated with sharing email information and mental health survey participation in two large population cohorts

Adams, M.; Hill, W. D.; Howard, D. M.; Davis, K. A. S.; Deary, I. J.; Hotopf, M.; McIntosh, A. M.

10.1101/471433 — genetics — Posted on 2019-04-23

890 Reduced structural connectivity in Insomnia Disorder

Jespersen, K. V.; Stevner, A.; Fernandes, H.; Soerensen, S. D.; Van Someren, E.; Kringelbach, M.; Vuust, P.

10.1101/510784 — neuroscience — Posted on 2019-04-23

891 Multi-stage models for the failure of complex systems, cascading disasters, and the onset of disease

Webster, A. J.

10.1101/476242 — cancer biology — Posted on 2019-04-23

892 deSALT: fast and accurate long transcriptomic read alignment with de Bruijn graph-based index

Liu, B.; Liu, Y.; Zang, T.; Wang, Y.

10.1101/612176 — bioinformatics — Posted on 2019-04-23

893 Genetic Monitoring and Molecular Phylogeny for Cymothoid Isopod Invasion in Egyptian Lake Qarun Fishes by Using adopted taxonomic marker (COI)

Hassan, M. A.

10.1101/614578 — genetics — Posted on 2019-04-22

894 Seasonal occurrence of diamondback moths Plutella xylostella and their parasitoid wasps Cotesia vestalis in greenhouses and their surrounding areas

Abe, J.; Uefune, M.; Yoneya, K.; Shiojiri, K.; Takabayashi, J.

10.1101/357814 — ecology — Posted on 2019-04-22

895 Maximum entropy framework for inference of cell population heterogeneity in signaling networks

Dixit, P.; Lyashenko, E.; Niepel, M.; Vitkup, D.

10.1101/137513 — systems biology — Posted on 2019-04-22

896 Comparison of Multi-objective Evolutionary Algorithms to Solve the Modular Cell Design Problem for Novel Biocatalysis

Garcia, S.; Trinh, C. T.

10.1101/616078 — synthetic biology — Posted on 2019-04-22

897 Are populations like a circuit? Comparing isolation by resistance to a new coalescent-based method

Lundgren, E.; Ralph, P. L.

10.1101/451328 — evolutionary biology — Posted on 2019-04-22

898 Spinal V2b neurons reveal a role for ipsilateral inhibition in speed control

Callahan, R. A.; Roberts, R.; Sengupta, M.; Kimura, Y.; Higashijima, S.-i.; Bagnall, M. W.

10.1101/615906 — neuroscience — Posted on 2019-04-22

899 Multifaceted Changes in Synaptic Composition and Astrocytic Involvement in a Mouse Model of Fragile X Syndrome

Simhal, A. K.; Zuo, Y.; Perez, M. M.; Madison, D. V.; Sapiro, G.; Micheva, K. D.

10.1101/615930 — neuroscience — Posted on 2019-04-22

900 Two Y chromosome-encoded genes determine sex in kiwifruit

Akagi, T.; Pilkington, S. M.; Varkonyi-Gasic, E.; Henry, I. M.; Sugano, S. S.; Sonoda, M.; Firl, A.; McNeilage, M. A.; Douglas, M. J.; Wang, T.; Redstock, R.; Voogd, C.; Datson, P.; Allan, A. C.; Beppu, K.; Kataoka, I.; Tao, R.

10.1101/615666 — plant biology — Posted on 2019-04-22

Best, C.; Zmudjak, M.; Ostersetzer, O.

10.1101/615856 — plant biology — Posted on 2019-04-22

902 The gene brain tumor constrains growth to ensure proper patterning during regeneration in Drosophila imaginal discs

Abidi, S. N. F.; Smith-Bolton, R. K.

10.1101/615948 — developmental biology — Posted on 2019-04-22

903 A model for reticular dysgenesis shows impaired sensory organ development and hair cell regeneration linked to cellular stress

Rissone, A.; Jimenez, E.; Bishop, K.; Carrington, B.; Slevin, C.; Wincovitch, S. M.; Sood, R.; Candotti, F.; Burgess, S.

10.1101/610204 — developmental biology — Posted on 2019-04-22

904 A genetic selection reveals functional metastable structures embedded in a toxin-encoding mRNA

Masachis, S.; Tourasse, N. J.; Lays, C.; Faucher, M.; Chabas, S.; Iost, I.; Darfeuille, F.

10.1101/615682 — molecular biology — Posted on 2019-04-22

905 Bioactivity-driven high throughput screening of microbiomes of medicinal plants for discovering new biological control agents

Iqrar, I.; Shinwari, Z.; El-Sayed, A.; Ali, G.

10.1101/611855 — microbiology — Posted on 2019-04-22

906 TonB dependent uptake of β-lactam antibiotics in the opportunistic human pathogen Stenotrophomonas maltophilia.

Calvopina, K.; Dulyayangkul, P.; Heesom, K. J.; Avison, M.

10.1101/615369 — microbiology — Posted on 2019-04-22

907 Stable maintenance of a hidden switch as a way to increase the gene expression stability

Kuwahara, H.; Gao, X.

10.1101/615500 — evolutionary biology — Posted on 2019-04-22

908 Revisiting Mitchell’s chemiosmotic theory in light of new stoichiometric reaction equations of ATPase II

Kushagra, A.

10.1101/615880 — biochemistry — Posted on 2019-04-22

909 Toward A Reproducible, Scalable Framework for Processing Large Neuroimaging Datasets

Johnson, E. C.; Wilt, M.; Rodriguez, L. M.; Norman-Tenazas, R.; Rivera, C.; Drenkow, N.; Kleissas, D.; LaGrow, T. J.; Cowley, H. P.; Downs, J.; Matelsky, J.; Hughes, M.; Reilly, E.; Wester, B.; Dyer, E.; Kording, K.; Gray-Roncal, W.

10.1101/615161 — neuroscience — Posted on 2019-04-22

910 Integrated analysis of the miRNA-mRNA network associated with LMP1 gene in nasopharyngeal carcinoma

Yang, Y.; Liu, W.; Zhang, Y.; Wu, S.; Luo, B.

10.1101/615237 — microbiology — Posted on 2019-04-22

911 High-powered detection of genetic effects on DNA methylation using integrated methylation QTL mapping and allele-specific analysis

Fan, Y.; Vilgalys, T. P.; Sun, S.; Peng, Q.; Tung, J.; Zhou, X.

10.1101/615039 — genomics — Posted on 2019-04-22

912 ModelTest-NG: a new and scalable tool for the selection of DNA and protein evolutionary models

Darriba, D.; Posada, D.; Kozlov, A. M.; Stamatakis, A.; Morel, B.; Flouri, T.

10.1101/612903 — bioinformatics — Posted on 2019-04-22

913 Catestatin improves insulin sensitivity in diet-induced obese mice: in vivo and in silico validation

Mahata, S. K.; Dasgupta, A.; Bandyopadhyay, K.; Ray, I.; Bandyopadhyay, G. K.; Chowdhury, N.; De, R. K.

10.1101/615997 — systems biology — Posted on 2019-04-22

914 Homeostatic mechanisms may shape the type and duration of oscillatory modulation.

Peterson, E. J.; Voytek, B.

10.1101/615450 — neuroscience — Posted on 2019-04-22

915 Clustering by phenotype and genome-wide association study in autism

Narita, A.; Nagai, M.; Mizuno, S.; Ogishima, S.; Tamiya, G.; Ueki, M.; Sakurai, R.; Makino, S.; Obara, T.; Ishikuro, M.; Yamanaka, C.; Matsubara, H.; Kuniyoshi, Y.; Murakami, K.; Kobayashi, T.; Kobayashi, M.; Usuzaki, T.; Ohseto, H.; Hozawa, A.; Kikuya, M.; Metoki, H.; Kure, S.; Kuriyama, S.

10.1101/614958 — neuroscience — Posted on 2019-04-22

916 The statistical structure of the hippocampal code for space as a function of time, context, and value

Lee, J. S.; Briguglio, J.; Romani, S.; Lee, A. K.

10.1101/615203 — neuroscience — Posted on 2019-04-22

917 Evaluation of Bacteria Detected in Both Urine and Open Wounds in Nursing Facility Residents

Libertucci, J.; Bassis, C.; Cassone, M.; Gibson, K. E.; Lansing, B.; Mody, L.; Young, V. B.; Meddings, J.

10.1101/614917 — microbiology — Posted on 2019-04-22

918 CreC Sensor Kinase Activation Enhances Growth of Escherichia coli in the Presence of Cephalosporins and Carbapenems.

Takebayashi, Y.; Taylor, E. S.; Whitwam, S.; Avison, M. B.

10.1101/615310 — microbiology — Posted on 2019-04-22

919 The rice leaf microbiome has a conserved community structure controlled by complex host-microbe interactions

Roman-reyna, V.; Pinili, D.; Borjaa, F. N.; Quibod, I. L.; Groen, S. C.; Mulyaningsih, E. S.; Rachmat, A.; Slamet-Loedin, I. H.; Alexandrov, N.; Mauleon, R.; Oliva, R.

10.1101/615278 — microbiology — Posted on 2019-04-22

920 Phylogenomics of Selaginellaceae with special reference to the enigmatic sanguinolenta group

Zhang, H.-R.; Wei, R.; Xiang, Q.-P.; Zhang, X.-C.

10.1101/615633 — evolutionary biology — Posted on 2019-04-22

921 A Simulation Study of mRNA Diffusion and Mitochondrial Localization

Horton, P.

10.1101/614883 — bioinformatics — Posted on 2019-04-22

922 A weighted sequence alignment strategy for gene structure annotation lift over from reference genome to a newly sequenced individual

Song, B.; Sang, Q.; Wang, H.; Pei, H.; Wang, F.; Gan, X.

10.1101/615476 — plant biology — Posted on 2019-04-22

923 Convolutional Neural Networks for Decoding of Covert Attention Focus and Saliency Maps for EEG Feature Visualization

Farahat, A.; Reichert, C.; Sweeney-Reed, C. M.; Hinrichs, H.

10.1101/614784 — neuroscience — Posted on 2019-04-22

924 TLR7-agonist and antineoplastic MEK1/2-inhibitor combination unlocks interferon responses from macrophages

Yang, L.; Ding, J. L.

10.1101/615609 — immunology — Posted on 2019-04-22

925 Stacks 2: Analytical Methods for Paired-end Sequencing Improve RADseq-based Population Genomics

Rochette, N. C.; Rivera-Colon, A. G.; Catchen, J. M.

10.1101/615385 — genomics — Posted on 2019-04-22

926 The Chinese chestnut genome: a reference for species restoration

Staton, M. E.; Addo-Quaye, C. A.; Cannon, N.; Sun, Y.; Zhebentyayeva, T.; Huff, M.; Fan, S.; Bellis, E.; Islam-Faridi, N. M.; Yu, J.; Henry, N.; Conrad, A.; Drautz-Moses, D. I.; Zhu, X.; Lu, Z.; Noorai, R. E.; Ficklin, S.; Saski, C.; Mandal, M.; Wagner, T. K.; Zembower, N.; Bodenes, C.; Holliday, J.; Westbrook, J.; Lasky, J. R.; Georgi, L.; Hebard, F.; Nelson, C. D.; Schuster, S. C.; Abbott, A. G.; Carlson, J. E.

10.1101/615047 — genomics — Posted on 2019-04-22

927 Multilayered N-glycoproteomics reveals impaired N-glycosylation promoting Alzheimer’s disease

Fang, P.; Xie, J.; Sang, S.; Zhang, L.; Liu, M.; Yang, L.; Xu, Y.; Yan, G.; Yao, J.; Gao, X.; Qian, W.; Wang, Z.; Zhang, Y.; Yang, P.; Shen, H.

10.1101/615989 — systems biology — Posted on 2019-04-22

928 TAPAS: A Thresholding Approach for Probability Map Automatic Segmentation in Multiple Sclerosis

Valcarcel, A.; Muschelli, J.; Pham, D.; Martin, M. L.; Yushkevich, P.; Calabresi, P.; Bakshi, R.; Shinohara, R.

10.1101/609156 — neuroscience — Posted on 2019-04-22

929 Effects of sugars and lipids on the growth and development of Caenorhabditis elegans

Wang, X.; Zhang, L.; Zhang, L.; Wang, W.; Wang, J.; Che, H.; Zhang, Y.

10.1101/615807 — genetics — Posted on 2019-04-22

930 The evolutionary advantage of toxin production among cyanobacteria, the oldest known organisms on Earth

Tristao Ramos, R. J.; Ionescu, C.-M.; Koca, J.

10.1101/615542 — bioinformatics — Posted on 2019-04-22

931 Logic-based Analysis of Gene Expression Data Predicts Pathway Crosstalk between TNF, TGFB1 and EGF in Basal-like Breast Cancer

Jo, K.; Santos Buitrago, B.; Kim, M.; Rhee, S.; Talcott, C.; Kim, S.

10.1101/614933 — bioinformatics — Posted on 2019-04-22

932 pathwayPCA: an R package for integrative pathway analysis with modern PCA methodology and gene selection

Odom, G.; Ban, Y.; Liu, L.; Sun, X.; Pico, A.; Zhang, B.; Wang, L.; Chen, X.

10.1101/615435 — bioinformatics — Posted on 2019-04-22

933 Creating a neuroprosthesis for active tactile exploration of textures

O'Doherty, J.; Shokur, S.; Medina, L. E.; Lebedev, M. A.; Nicolelis, M. A. L.

10.1101/594994 — neuroscience — Posted on 2019-04-22

934 ATP synthase K+- and H+-flux drive ATP synthesis and enable mitochondrial K+-uniporter function

Juhaszova, M.; Kobrinsky, E.; Zorov, D. B.; Nuss, B.; Yaniv, Y.; Fishbein, K. W.; de Cabo, R.; Montoliu, L.; Gabelli, S. B.; Aon, M. A.; Cortassa, S.; Sollott, S. J.

10.1101/355776 — biophysics — Posted on 2019-04-22

935 Balancing selection shapes the Intracellular Pathogen Response in natural Caenorhabditis elegans populations

van Sluijs, L.; Bosman, K. J.; Pankok, F.; Blokhina, T.; Riksen, J. A. G.; Snoek, B.; Pijlman, G. P.; Kammenga, J. E.; Sterken, M. G.

10.1101/579151 — genetics — Posted on 2019-04-22

936 Effects of two centuries of global environmental variation on phenology and physiology of Arabidopsis thaliana

DeLeo, V. L.; Menge, D. N. L.; Hanks, E. M.; Juenger, T. E.; Lasky, J. R.

10.1101/424242 — ecology — Posted on 2019-04-22

937 96 Eyes: Parallel Fourier Ptychographic Microscopy for high-throughput screening

Chan, A. C. S.; Kim, J.; Pan, A.; Xu, H.; Nojima, D.; Hale, C.; Wang, S.; Yang, C.

10.1101/547265 — bioinformatics — Posted on 2019-04-22

938 Ancient hybridization and adaptive introgression of an invadolysin gene in schistosome parasites

Platt, R. N.; McDew-White, M.; Le Clec'h, W.; Chevalier, F. D.; Allan, F.; Emery, A. M.; Garba, A.; Hamidou, A.; Ame, S. M.; Webster, J. P.; Rollinson, D.; Webster, B. L.; Anderson, T. J. C.

10.1101/539353 — evolutionary biology — Posted on 2019-04-22

939 CliqueSNV: Scalable Reconstruction of Intra-Host Viral Populations from NGS Reads

Knyazev, S.; Tsyvina, V.; Melnyk, A.; Artyomenko, A.; Malygina, T.; Porozov, Y. B.; Campbell, E.; Switzer, W. M.; Skums, P.; Zelikovsky, A.

10.1101/264242 — bioinformatics — Posted on 2019-04-22

940 VOLARE: Visual analysis of disease-associated microbiome-immune system interplay

Siebert, J. C.; Neff, C. P.; Schneider, J. M.; Regner, E. H.; Ohri, N.; Kuhn, K. A.; Palmer, B. E.; Lozupone, C. A.; Gorg, C.

10.1101/431379 — bioinformatics — Posted on 2019-04-22

941 TMS-evoked oscillations in human cortical circuits: A search for natural frequencies

Stanfield, C. T.; Wiener, M.

10.1101/614826 — neuroscience — Posted on 2019-04-22

942 Enriched environmental conditions modify the gut microbiome composition and fecal markers of inflammation in Parkinson’s disease

Singh, Y.; Hadidi, M. E.; Matthes, J.; Wassouf, Z.; Schulze-Hentrich, J. M.; Kohlhofer, U.; Quintanilla-Martinez de Fend, L.; Huson, D.; Riess, O.; Casadei, N.

10.1101/614834 — neuroscience — Posted on 2019-04-22

943 White-nose syndrome restructures bat skin microbiomes

Ange-Stark, M. A.; Cheng, T. L.; Hoyt, J. R.; Langwig, K. E.; Parise, K. L.; Frick, W. F.; Kilpatrick, A. M.; MacManes, M. D.; Foster, J. T.

10.1101/614842 — microbiology — Posted on 2019-04-22

944 NCBP2-mediated apoptosis contributes to developmental defects of the schizophrenia-associated 3q29 deletion

Singh, M. D.; Jensen, M.; Lasser, M.; Huber, E.; Yusuff, T.; Pizzo, L.; Lifschutz, B.; Desai, I.; Kubina, A.; Yennawar, S.; Kim, S.; Iyer, J.; Rincon-Limas, D. E.; Lowery, L. A.; Girirajan, S.

10.1101/614750 — genomics — Posted on 2019-04-22

945 Demographic Model for Inheritable Cardiac Disease

Burghardt, T. P.

10.1101/614735 — bioinformatics — Posted on 2019-04-22

946 Excess significance bias in repetitive transcranial magnetic stimulation literature for neuropsychiatric disorders

Amad, A.; Jardri, R.; Rousseau, C.; Larochelle, Y.; Ioannidis, J. P.; Naudet, F.

10.1101/614230 — scientific communication and education — Posted on 2019-04-22

947 Silencing cryptic specialized metabolism in Streptomyces by the nucleoid-associated protein Lsr2

Gehrke, E. J.; Zhang, X.; Pimentel-Elardo, S. M.; Johnson, A. R.; Rees, C. A.; Jones, S. E.; Hindra, ; Gehrke, S. S.; Turvey, S.; Boursalie, S.; Hill, J. E.; Carlson, E. E.; Nodwell, J. R.; Elliot, M. A.

10.1101/614727 — microbiology — Posted on 2019-04-22

948 The Community Simulator: A Python package for microbial ecology

Marsland, R.; Cui, W.; Goldford, J.; Mehta, P.

10.1101/613836 — ecology — Posted on 2019-04-22

949 Phenological matching drives wheat pest range shift under climate change

Wu, Y.; Gong, Z.; Bebber, D.; Miao, J.; Zhao, Z.; Jiang, Y.; Xiao, S.; Zhang, G.; Yu, D.; Fang, J.; Lu, X.; Lei, C.; Ding, J.; Wang, Q.; Jiang, Y.; Li, T.; Lian, H.; Li, H.; Duan, Y.; Huang, J.; Jin, D.; He, Y.; Zhang, Z.; Zhang, Y.; Chen, J.; Qiao, H.; Huang, W.

10.1101/614743 — ecology — Posted on 2019-04-22

950 Predicting the conservation status of Europe’s Data Deficient sharks and rays

Walls, R. H. L.; Dulvy, N. K.

10.1101/614776 — ecology — Posted on 2019-04-22

951 Kidney osteoclast factors and matrix metalloproteinase expression in a mice model of diet-induced obesity and diabetes.

dos Santos-Macedo, F.; Martins-Gregorio, B.; Cardozo Paes de Almeida, E.; de Souza Mendonca, L.; de Souza Azevedo, R.; Fernandes-Santos, C.

10.1101/615716 — pathology — Posted on 2019-04-22

952 Brown adipose tissue remodeling precedes cardiometabolic abnormalities independent of overweight in fructose-fed mice

Queiroz Machado, T.; Cristina Pereira-Silva, D.; Ferreira Goncalves, L.; Fernandes-Santos, C.

10.1101/615674 — pathology — Posted on 2019-04-22

953 Chemosensory proteins in the CSP4 clade evolved as plant immunity suppressors before two suborders of plant-feeding hemipteran insects diverged

Drurey, C.; Mathers, T. C.; Prince, D. C.; Wilson, C.; Caceres-Moreno, C.; Mugford, S. T.; Hogenhout, S. A.

10.1101/173278 — evolutionary biology — Posted on 2019-04-22

954 The Minimum Environmental Perturbation Principle: A New Perspective on Niche Theory

Marsland, R.; Cui, W.; Mehta, P.

10.1101/531640 — ecology — Posted on 2019-04-22

955 Fast and Accurate Clustering of Single Cell Epigenomes Reveals Cis-Regulatory Elements in Rare Cell Types

Fang, R.; Preissl, S.; Hou, X.; Lucero, J.; Wang, X.; Motamedi, A.; Shiau, A. K.; Mukamel, E. A.; Zhang, Y.; Behrens, M. M.; Ecker, J.; Ren, B.

10.1101/615179 — bioinformatics — Posted on 2019-04-22

956 Direct Comparative Analysis of 10X Genomics Chromium and Smart-seq2

Wang, X.; Yao, H.; Zhang, Q.; Ren, X.; Zhang, Z.

10.1101/615013 — bioinformatics — Posted on 2019-04-22

957 Caldicellulosiruptor bescii regulates pilus expression in response to the polysaccharide, xylan

Khan, A. M. A. M.; Hauk, V. J.; Raffel, T.; Blumer-Schuette, S. E.

10.1101/614800 — microbiology — Posted on 2019-04-22

958 Microclimate and larval habitat density predict adult Aedes albopictus abundance in urban areas

Evans, M. V.; Hintz, C. W.; Jones, L.; Shiau, J.; Solano, N.; Drake, J. M.; Murdock, C. C.

10.1101/615625 — ecology — Posted on 2019-04-22

959 Genetic Monitoring and Molecular Phylogeny for Cymothoid Isopod Invasion in Egyptian Lake Qarun Fishes by Using adopted taxonomic marker (COI)

Hassan, M. A.

10.1101/614578 — genetics — Posted on 2019-04-22

960 The Molecular Basis for Nestmate Recognition in the Eusocial Ant Camponotus floridanus

Ferguson, S. T.; Park, K. Y.; Ruff, A.; Zwiebel, L. J.

10.1101/614719 — ecology — Posted on 2019-04-22

961 Phigaro: high throughput prophage sequence annotation

Starikova, E. V.; Tikhonova, P. O.; Prianichnikov, N. A.; Rands, C. M.; Zdobnov, E. M.; Govorun, V. M.

10.1101/598243 — bioinformatics — Posted on 2019-04-22

962 Network-based imputation of dropouts in single-cell RNA sequencing data

Leote, A. C.; Wu, X.; Beyer, A.

10.1101/611517 — bioinformatics — Posted on 2019-04-22

963 No evidence for disruption of global patterns of nest predation in shorebirds

Bulla, M.; Reneerkens, J.; Weiser, E. L.; Sokolov, A.; Taylor, A. R.; Sittler, B.; McCaffery, B. J.; Ruthrauff, D. R.; Catlin, D. H.; Payer, D. C.; Ward, D. H.; Solovyeva, D. V.; Santos, E. S.; Rakhimberdiev, E.; Nol, E.; Kwon, E.; Brown, G. S.; Hevia, G. D.; Gates, H. R.; Johnson, J. A.; van Gils, J. A.; Hansen, J.; Lamarre, J.-F.; Rausch, J.; Conklin, J. R.; Liebezeit, J.; Bety, J.; Lang, J.; Alves, J. A.; Fernandez-Elipe, J.; Michael-Exo, K.; Bollache, L.; Bertellotti, M.; Giroux, M.-A.; van de Pol, M.; Johnson, M.; Boldenow, M. L.; Valcu, M.; Soloviev, M.; Sokolova, N.; Senner, N. R.; Leco

10.1101/601047 — ecology — Posted on 2019-04-22

964 Can immunosuppressed mice control oral infection by the opportunistic pathogen Encephalitozoon intestinalis?

Moura, M. L. d. C.; Alvares-Saraiva, A. M.; Perez, E. C.; Xavier, J. G.; Spadacci-Morena, D. D.; Moyses, C. R. S.; Dell'Armelina Rocha, P. R.; Lallo, M. A.

10.1101/611988 — pathology — Posted on 2019-04-22

965 Synaptic weight decay with selective consolidation enables fast learning without catastrophic forgetting

Leimer, P.; Herzog, M.; Senn, W.

10.1101/613265 — neuroscience — Posted on 2019-04-22

966 A confirmation bias in perceptual decision-making due to hierarchical approximate inference

Lange, R. D.; Chattoraj, A.; Beck, J.; Yates, J.; Haefner, R.

10.1101/440321 — animal behavior and cognition — Posted on 2019-04-22

967 Characterization of a vascular bundle localizing Gossypium hirsutum NAC4 transcription factor promoter for its role in environmental stress responses

Trishla, S. V.; Marriboina, S.; Boyidi, P.; Gudipalli, P.; Kirti, P. B.

10.1101/510578 — plant biology — Posted on 2019-04-22

968 GAPIN: Grouped and Aligned Protein Interface Networks

Araujo, B. M.; Coelho, A. L.; Silveira, S. d. A.; Romanelli, J. P. R.; Minardi, R. C. d. M.; Silveira, C. H.

10.1101/520833 — bioinformatics — Posted on 2019-04-22

969 Whole-genome reference panel of 1,781 Northeast Asians improves imputation accuracy of rare and low-frequency variants

Yoo, S.-K.; Kim, C.-U.; Kim, H. L.; Kim, S.; Shin, J.-Y.; Kim, N.; Yang, J. S.; Lo, K.-W.; Cho, B.; Matsuda, F.; Schuster, S. C.; Kim, C.; Kim, J.-I.; Seo, J.-S.

10.1101/600353 — genomics — Posted on 2019-04-22

970 Lessons and recommendations from three decades as an NSF REU Site: A call for systems-based assessment

McDevitt, A. L.; Patel, M. V.; Ellison, A.

10.1101/162289 — scientific communication and education — Posted on 2019-04-21

971 Functional specialization under multidimensional tradeoffs

Amado, A.; Campos, P.

10.1101/492173 — ecology — Posted on 2019-04-21

972 Single cell RNA sequencing reveals cellular diversity of trisomy 21 retina

Wu, J.; Ding, X.; Hu, F.; Xu, Z.; Zhang, S.; Liang, L.; Chai, C.; Zhong, J.; Wang, S.; Lin, X.; Chen, Y.; Feng, Q.; Zhu, J.; Jiang, S.; Xia, J.; Li, W.; Gao, Y.; Li, J.; Zhang, J.; He, Z.; Xue, S.; Guo, G.; Xu, P.; Gao, F.; Wang, D.; Zhang, D.; Chen, D.; Sun, X.; Chen, F.

10.1101/614149 — cell biology — Posted on 2019-04-21

973 Amygdala Reward Neurons Form and Store Fear Extinction Memory

Zhang, X.; Kim, J.; Tonegawa, S.

10.1101/615096 — neuroscience — Posted on 2019-04-21

974 The Viral Protein Corona Directs Viral Pathogenesis and Amyloid Aggregation

Ezzat, K.; Pernemalm, M.; Palsson, S.; Roberts, T. C.; Jarver, P.; Dondalska, A.; Bestas, B.; Sobkowiak, M. J.; Levanen, B.; Skold, M.; Thompson, E. A.; Saher, O.; Kari, O. K.; Lajunen, T.; Sverremark Ekstrom, E.; Nilsson, C.; Ishchenko, Y.; Malm, T.; Wood, M. J. A.; Power, U. F.; Masich, S.; Linden, A.; Sandberg, J. K.; Lehtio, J.; Spetz, A.-L.; Andaloussi, S. E.

10.1101/246785 — microbiology — Posted on 2019-04-21

975 Validation of a Miniaturized Permeability Assay Compatible with CRISPR-Mediated Genome-Wide Screen

Simonneau, C.; Yang, J.; Kong, X.; Kilker, R.; Edelstein, L.; Fortina, P.; Londin, E.; Horowitz, A.

10.1101/471854 — cell biology — Posted on 2019-04-21

976 Statistical Analysis of Variability in TnSeq Data Across Conditions Using Zero-Inflated Negative Binomial Regression

Subramaniyam, S.; DeJesus, M. A.; Zaveri, A.; Smith, C. M.; Baker, R. E.; Ehrt, S.; Schnappinger, D.; Sassetti, C. M.; Ioerger, T. R.

10.1101/590281 — bioinformatics — Posted on 2019-04-21

977 Partial FMRP expression is sufficient to normalize neuronal hyperactivity in Fragile X neurons

Graef, J. D.; Wu, H.; Ng, C.; Sun, C.; Villegas, V.; Qadir, D.; Jesseman, K.; Warren, S.; Jaenisch, R.; Cacace, A.; Wallace, O.

10.1101/608331 — neuroscience — Posted on 2019-04-21

978 PD-L1:CD80 Heterodimer Triggers CD28 While Repressing Both PD-1 and CTLA4 Pathways

Zhao, Y.; Lin, C.-H.; Lee, C.; Xu, X.; Huang, Z.; Xiao, C.; Bui, J.; Lu, L.-F.; Hui, E.

10.1101/615138 — immunology — Posted on 2019-04-21

979 Amelioration of muscular dystrophy phenotype in mdx mice by inhibition of Flt1

Verma, M.; Shimizu-Motohashi, Y.; Asakura, Y.; Ennen, J.; Bosco, J.; Zou, Z.; Fong, G.-H.; Josiah, S.; Keefe, D.; Asakura, A.

10.1101/609735 — developmental biology — Posted on 2019-04-21

980 PSL-Recommender: Protein Subcellular Localization Prediction using Recommender System

Jamali, R.; Eslahchi, C.; Jahangiri-Tazehkand, S.

10.1101/462812 — bioinformatics — Posted on 2019-04-21

981 Fusarium verticillioides SNARE protein FvSyn1 harbors two key functional motifs that play selective roles in fungal development and virulence

Zhang, H.; Yan, H.; Shim, W. B.

10.1101/615211 — molecular biology — Posted on 2019-04-21

982 Statistically consistent divide-and-conquer pipelines for phylogeny estimation using NJMerge

Molloy, E. K.; Warnow, T.

10.1101/469130 — evolutionary biology — Posted on 2019-04-21

983 Solution of the FISH-Hi-C paradox for Human Interphase Chromosomes

Thirumalai, D.; Shi, G.

10.1101/615120 — biophysics — Posted on 2019-04-21

984 Normal development and fertility of Fut1, Fut2, and Sec1 triple knockout mice

Chen, J.; Zhang, C.; Su, Z.; Li, F. L.; Hwu, P.; Wang, Z.; Wang, Y.; Li, Y.; Tong, J.; Chen, C.; Zhou, D.

10.1101/615070 — biochemistry — Posted on 2019-04-21

985 Rho-kinase planar polarisation at tissue boundaries depends on phospho-regulation of membrane residence time

Sidor, C.; Stevens, T. J.; Jin, L.; Boulanger, J.; Roeper, K.

10.1101/615062 — developmental biology — Posted on 2019-04-21

986 Organising the cell cycle in the absence of transcriptional control: Dynamic phosphorylation co-ordinates the Trypanosoma brucei cell cycle post-transcriptionally

Benz, C.; Urbaniak, M. D.

10.1101/615351 — cell biology — Posted on 2019-04-21

987 Internal friction can be measured with the Jarzynski equality

Kailasham, R.; Chakrabarti, R.; Jagadeeshan, R.

10.1101/613091 — biophysics — Posted on 2019-04-21

988 An improved method to produce clinical scale natural killer cells from human pluripotent stem cells

Zhu, H.; Kaufman, D. S.

10.1101/614792 — immunology — Posted on 2019-04-21

989 UNC-45A is preferentially expressed in epithelial cells and binds to and co-localizes with interphase MTs

Habicht, J.; Mooneyham, A.; Shetty, M.; Zhang, X.; Shridhar, V.; Winterhoff, B.; Zhang, Y.; Cepela, J.; Starr, T.; Lou, E.; Bazzaro, M.

10.1101/615187 — cell biology — Posted on 2019-04-21

990 VULCAN integrates ChIP-seq with patient-derived co expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer

Holding, A. N.; Giorgi, F. M.; Donnelly, A.; Cullen, A. E.; Nagarajan, S.; Selth, L. A.; Markowetz, F.

10.1101/266908 — cancer biology — Posted on 2019-04-21

991 A Genetically Encoded Fluorescent Sensor Enables Real-time Detection of the Intracellular GTP:GDP Ratio

Zhang, J.; Song, Y.; Liu, S.; Wang, W.; Zhang, M.; Yang, G.; Zou, P.; Wang, J.

10.1101/614412 — biochemistry — Posted on 2019-04-21

992 Superlets: time-frequency super-resolution using wavelet sets

Moca, V. V.; Nagy-Dabacan, A.; Barzan, H.; Muresan, R. C.

10.1101/583732 — neuroscience — Posted on 2019-04-21

993 Unpredictable effects of the genetic background of transgenic lines in physiological quantitative traits

Evangelou, A.; Ignatiou, A.; Antoniou, C.; Kalanidou, S.; Chatzimatthaiou, S.; Shianiou, G.; Ellina, S.; Athanasiou, R.; Panagi, M.; Apidianakis, Y.; Pitsouli, C.

10.1101/494419 — genetics — Posted on 2019-04-21

994 A Method for Cost-Effective and Rapid Characterization of Engineered T7-based Transcription Factors by Cell-Free Protein Synthesis Reveals Insights into the Regulation of T7 RNA Polymerase-Driven Expression

McManus, J.; Murray, R.; Emanuel, P.; Lux, M.

10.1101/614545 — synthetic biology — Posted on 2019-04-20

995 3,3′-Diindolylmethane Dose-Dependently Prevents Advanced Prostate Cancer

Li, Y.; Mahloch, N. W.; Starkey, N. J. E.; Pena-Luna, M.; Rottinghaus, G. E.; Fritsche, K. L.; Besch-Williford, C.; Lubahn, D. B.

10.1101/612929 — cancer biology — Posted on 2019-04-21

996 Machine learning predicts rapid relapse of triple negative breast cancer

Zhang, Y.; Nock, W.; Wyse, M.; Weber, Z.; Adams, E.; Stockard, S.; Tallman, D.; Asad, S.; Winer, E. P.; Lin, N. U.; Cherian, M.; Lustberg, M.; Ramaswamy, B.; Sardesai, S.; Vandeusen, J.; Williams, N.; Wesolowski, R.; Stover, D. G.

10.1101/613604 — cancer biology — Posted on 2019-04-21

997 A self-administered, artificial intelligence (AI) platform for cognitive assessment in multiple sclerosis (MS)

Khaligh-Razavi, S.-M.; Sadeghi, M.; Khanbagi, M.; Kalafatis, C.; Nabavi, S. M.

10.1101/611335 — neuroscience — Posted on 2019-04-20

998 Benchmarking algorithms for genomic prediction of complex traits

Azodi, C.; McCarren, A.; Roantree, M.; de los Campos, G.; Shiu, S.-H.

10.1101/614479 — genetics — Posted on 2019-04-20

999 Decoding Complex Sounds Using Broadband Population Recordings from Secondary Auditory Cortex of Macaques

Heelan, C.; Lee, J.; O'Shea, R.; Brandman, D. M.; Truccolo, W.; Nurmikko, A. V.

10.1101/614248 — neuroscience — Posted on 2019-04-20

1000 Single and population coding of taste in the gustatory cortex of awake mice

Levitan, D.; Lin, J.-Y.; Wachutka, J.; Mukherjee, N.; Nelson, S. B.; Katz, D. B.

10.1101/575522 — neuroscience — Posted on 2019-04-20

1001 CyMIRA: The Cytonuclear Molecular Interactions Reference for Arabidopsis

Forsythe, E. S.; Sharbrough, J.; Havird, J. C.; Warren, J. M.; Sloan, D. B.

10.1101/614487 — genomics — Posted on 2019-04-20

1002 Walking kinematics in the polymorphic seed harvester ant Messor barbarus: influence of ant size and load carriage

Merienne, H.; Latil, G.; Moretto, P.; Fourcassie, V.

10.1101/614362 — animal behavior and cognition — Posted on 2019-04-20

1003 Tunable integrase-mediated differentiation facilitates improved output of burdensome functions in E. coli

Williams, R. L.; Murray, R. M.

10.1101/614529 — synthetic biology — Posted on 2019-04-20

1004 The ancillary N-terminal region of the yeast AP-1 transcription factor Yap8 contributes to its DNA binding specificity

Maciaszczyk-Dziubinska, E.; Reymer, A.; Kumar, N. V.; Białek, W.; Mizio, K.; Tamas, M. J.; Wysocki, R.

10.1101/614503 — genetics — Posted on 2019-04-20

1005 Severe Biallelic Loss-of-function Mutations in Nicotinamide Mononucleotide Adenylyltransferase 2 (NMNAT2) in Two Fetuses with Fetal Akinesia Deformation Sequence

Lukacs, M.; Gilley, J.; Zhu, Y.; Orsomando, G.; Angeletti, C.; Liu, J.; Yang, X.; Park, J.; Hopkin, R. J.; Coleman, M. P.; Zhai, R. G.; Stottmann, R. W.

10.1101/610899 — genetics — Posted on 2019-04-20

1006 Modulating Fis and IHF binding specificity, crosstalk and regulatory logic through the engineering of complex promoters

Monteiro, L. M. O.; Sanches-Medeiros, A.; Westmann, C.; Silva-Rocha, R.

10.1101/614396 — synthetic biology — Posted on 2019-04-20

1007 Genetic differentiation and intrinsic genomic features explain variation in recombination hotspots among cocoa tree populations

Cornejo, O. E.; Motamayor, J. C.; Schwarzkopf, E. J.

10.1101/482299 — genomics — Posted on 2019-04-20

1008 Instability of the pseudoautosomal boundary in house mice

Morgan, A. P.; Bell, T. A.; Crowley, J. J.; Pardo Manuel de Villena, F.

10.1101/561951 — genetics — Posted on 2019-04-20

1009 Skeletal descriptions of shape provide unique perceptual information for object recognition

Ayzenberg, V.; Lourenco, S. F.

10.1101/518795 — neuroscience — Posted on 2019-04-20

1010 Using Biogeography to Assess Key Adaptation Strength in Two Bird Families

Halloway, A.; Whelan, C. J.; Sekercioglu, C. H.; Brown, J. S.

10.1101/214148 — ecology — Posted on 2019-04-20

1011 Targeted mRNA demethylation using an engineered dCas13b-ALKBH5 fusion protein

Li, J.; Chen, Z.; Chen, F.; Ling, Y.; Peng, Y.; Luo, N.; Wang, H.

10.1101/614859 — cell biology — Posted on 2019-04-20

1012 Behavioural analysis of single-cell aneural ciliate, Stentor roeselii, using machine learning approaches

Trinh, K. M.; Wayland, M.; Prabakaran, S.

10.1101/594796 — animal behavior and cognition — Posted on 2019-04-20

1013 Single cell RNA sequencing reveals cellular diversity of trisomy 21 retina

Chen, F.; Sun, X.; Chen, D.; Wu, J.; Ding, X.; Hu, F.; Xu, Z.; Zhang, S.; Liang, L.; Chai, C.; Zhong, J.; Wang, S.; Zhu, J.; Lin, X.; Chen, Y.; Feng, Q.; Jiang, S.; Li, W.; Li, J.; Xia, J.; Gao, Y.; Zhang, J.; He, Z.; Xue, S.; Guo, G.; Xu, P.; Gao, F.; Wang, D.; Zhang, D.

10.1101/614149 — cell biology — Posted on 2019-04-20

1014 A How-To guide to: Quantitative high-speed video profiling to discriminate between variants of primary ciliary dyskinesia

Chioccioli, M.; Feriani, L.; nguyen, q.; Kotar, J.; Dell, S. D.; Mennella, V.; Amirav, I.; Cicuta, P.

10.1101/614966 — cell biology — Posted on 2019-04-20

1015 Intertwined trade-offs coordinate Drosophila midgut mitosis vs. endoreplication and host defense vs. dysplasia

Tamamouna, V.; Panagi, M.; Theophanous, A.; Demosphenous, M.; Michail, M.; Papadopoulou, M.; Teloni, S.; Pitsouli, C.; Apidianakis, Y.

10.1101/615104 — cell biology — Posted on 2019-04-20

1016 Functional Genomic Complexity Defines Intratumor Heterogeneity and Tumor Aggressiveness in Liver Cancer

Kwon, S. M.; Budhu, A.; Woo, H. G.; Chaisaingmongkol, J.; Dang, H.; Forgues, M.; Harris, C. C.; Zhang, G.; Auslander, N.; Ruppin, E.; Mahidol, C.; Ruchirawa, M.; Wang, X. W.

10.1101/614057 — genomics — Posted on 2019-04-20

1017 Radiator: a cloud-based framework for deploying reusable bioinformatics tools

Lo, E. K.; Schwab, R. M.; Burke, Z.; Cahan, P.

10.1101/614594 — bioinformatics — Posted on 2019-04-20

1018 Comprehensive Classification of the RNaseH-like domain-containing Proteins in Plants

Li, S.; Liu, K.; Sun, Q.

10.1101/572842 — plant biology — Posted on 2019-04-20

1019 Dogs, but not wolves, lose their sensitivity towards novelty with age

Hansen Wheat, C.; van der Bijl, W.; Temrin, H.

10.1101/405480 — animal behavior and cognition — Posted on 2019-04-20

1020 Direct observation of branching MT nucleation in living animal cells.

Verma, V.; Maresca, T. J.

10.1101/613463 — cell biology — Posted on 2019-04-19

1021 Many unreported crop pests and pathogens are probably already present

Bebber, D. P.; Field, E. M.; Gui, H.; Mortimer, P.; Holmes, T.; Gurr, S. J.

10.1101/519223 — ecology — Posted on 2019-04-19

1022 PBS3 is the missing link in plant-specific isochorismate-derived salicylic acid biosynthesis

Rekhter, D.; Luedke, D.; Ding, Y.; Feussner, K.; Zienkiewicz, K.; Lipka, V.; Wiermer, M.; Zhang, Y.; Feussner, I.

10.1101/600692 — plant biology — Posted on 2019-04-19

1023 Post-saccadic face processing is modulated by pre-saccadic preview: Evidence from fixation-related potentials

Buonocore, A.; Dimigen, O.; Melcher, D.

10.1101/610717 — neuroscience — Posted on 2019-04-19

1024 Experience-dependent development and maintenance of binocular neurons in the mouse visual cortex

Jenks, K. R.; Shepherd, J. R.

10.1101/614768 — neuroscience — Posted on 2019-04-19

1025 Validation of new bioinformatic tools to identify expanded repeats: a non-reference intronic pentamer expansion in RFC1 causes CANVAS

Rafehi, H.; Szmulewicz, D.; Bennett, M.; Sobreira, N.; Pope, K.; Smith, K.; Gillies, G.; Diakumis, P.; Dolzhenko, E.; Eberle, M.; Barcina, M. G.; Breen, D.; Chancellor, A.; Cremer, P.; Delatycki, M.; Fogel, B.; Hackett, A.; Halmagyi, G. M.; Kapetanovic, S.; Lang, A.; Mossman, S.; Mu, W.; Patrikios, P.; Perlman, S.; Rosemargy, I.; Storey, E.; Watson, S.; Wilson, M.; Zee, D.; Valle, D.; Amor, D.; Bahlo, M.; Lockhart, P. J.

10.1101/597781 — genetics — Posted on 2019-04-19

1026 A reference map of the human protein interactome

Luck, K.; Kim, D.-K.; Lambourne, L.; Spirohn, K.; Begg, B. E.; Bian, W.; Brignall, R.; Cafarelli, T.; Campos-Laborie, F. J.; Charloteaux, B.; Choi, D.; Cote, A. G.; Daley, M.; Deimling, S.; Desbuleux, A.; Dricot, A.; Gebbia, M.; Hardy, M. F.; Kishore, N.; Knapp, J. J.; Kovacs, I. A.; Lemmens, I.; Mee, M. W.; Mellor, J. C.; Pollis, C.; Pons, C.; Richardson, A. D.; Schlabach, S.; Teeking, B.; Yadav, A.; Babor, M.; Balcha, D.; Basha, O.; Bowman-Colin, C.; Chin, S.-F.; Choi, S. G.; Colabella, C.; Coppin, G.; D'Amata, C.; De Ridder, D.; De Rouck, S.; Duran-Frigola, M.; Ennajdaoui, H.; Goebels, F.;

10.1101/605451 — systems biology — Posted on 2019-04-19

1027 Differential coupling of parvalbumin and somatostatin interneurons with adult-born granule cells

Yang, S.-m.; Groisman, A.; Schinder, A.

10.1101/598615 — neuroscience — Posted on 2019-04-19

1028 Skeletal descriptions of shape provide unique perceptual information for object recognition

Ayzenberg, V.; Lourenco, S. F.

10.1101/518795 — neuroscience — Posted on 2019-04-19

1029 HMMRATAC: a Hidden Markov ModeleR for ATAC-seq

Tarbell, E. D.; Liu, T.

10.1101/306621 — bioinformatics — Posted on 2019-04-19

1030 A Plant-Specific Polarity Module Establishes Cell Fate Asymmetry in the Arabidopsis Stomatal Lineage

Rowe, M.; Dong, J.; Weimer, A.; Bergmann, D.

10.1101/614636 — plant biology — Posted on 2019-04-19

1031 Crosslinking actin networks produces compressive force

Ma, R.; Berro, J.

10.1101/614453 — biophysics — Posted on 2019-04-19

1032 Optimal Mass Transport Kinetic Modeling for Head and Neck DCE-MRI: Initial Analysis

Elkin, R.; Nadeem, S.; LoCastro, E.; Paudyal, R.; Hatzoglou, V.; Lee, N.; Shukla-Dave, A.; Deasy, J. O.; Tannenbaum, A.

10.1101/612770 — systems biology — Posted on 2019-04-19

1033 Maximal homology alignment: A new method based on two-dimensional homology

Erives, A. J.

10.1101/593228 — genetics — Posted on 2019-04-19

1034 RanGTP regulates cilium formation and ciliary trafficking of a kinesin-II subunit independent of its nuclear functions

Huang, S.; Avasthi, P.

10.1101/562272 — cell biology — Posted on 2019-04-19

1035 Functional promoter polymorphisms govern the differential expression of HMG-CoA Reductase gene in rat models of essential hypertension

Ali Khan, A.; Sundar, P.; Gupta, V.; Arige, V.; Reddy, S. S.; Dikshit, M.; Barthwal, M. K.; Mahapatra, N. R.

10.1101/614669 — molecular biology — Posted on 2019-04-19

1036 Spontaneously Arising Streptococcus mutans Variants With Reduced Susceptibility to Chlorhexidine Display Genetic Defects and Diminished Fitness

Kaspar, J. R.; Godwin, M. J.; Velsko, I. M.; Richards, V. P.; Burne, R. A.

10.1101/528471 — microbiology — Posted on 2019-04-19

1037 Rethinking the fundamental unit of ecological remote sensing: Estimating individual level plant traits at scale

Marconi, S.; Graves, S.; Weinstein, B.; Bohlman, S.; White, E.

10.1101/556472 — ecology — Posted on 2019-04-19

1038 From skylight input to behavioural output: a computational model of the insect polarised light compass

Gkanias, E.; Risse, B.; Mangan, M.; Webb, B.

10.1101/504597 — animal behavior and cognition — Posted on 2019-04-19

1039 Transcriptomic response to divergent selection for flowering time in maize reveals convergence and key players of the underlying gene regulatory network

Tenaillon, M. I.; Seddiki, K.; Mollion, M.; Le Guilloux, M.; Marchadier, E.; Ressayre, A.; Dillmann, C.

10.1101/461947 — plant biology — Posted on 2019-04-19

1040 ShuTu: Open-Source Software for Efficient and Accurate Reconstruction of Dendritic Morphology

Jin, D. Z.; Zhao, T.; Hunt, D. L.; Pearcy, R.; Hsu, C.-L.; Spruston, N.

10.1101/226548 — neuroscience — Posted on 2019-04-19

1041 Broken force dispersal network in tip-links by the mutations induces hearing-loss

Hazra, J. P.; Sagar, A.; Arora, N.; Deb, D.; Kaur, S. P.; Rakshit, S.

10.1101/614610 — biophysics — Posted on 2019-04-19

1042 Ultraviolet light degrades the mechanical and structural properties of human stratum corneum

Lipsky, Z. W.; German, G. K.

10.1101/614602 — biophysics — Posted on 2019-04-19

1043 Small molecule inhibitors of a human recombination-associated ATPase, RAD54

Ehmsen, K. T.; Ang, K. K. H.; Wright, W. D.; Davies, J. L.; Younis, Y.; Birman, Y.; Bryant, C.; Gallardo-Godoy, A.; Renslo, A. R.; Neitz, R. J.; Arkin, M. R.; Heyer, W.-D.

10.1101/614586 — biochemistry — Posted on 2019-04-19

1044 Extended haplotype phasing of de novo genome assemblies with FALCON-Phase

Kronenberg, Z. N.; Rhie, A.; Koren, S.; Concepcion, G.; Peluso, P.; Munson, K.; Hiendleder, S.; Fedrigo, O.; Jarvis, E.; Phillippy, A.; Eichler, E.; Williams, J.; Smith, T. P. L.; Hall, R.; Sullivan, S. T.; Kingan, S. B.

10.1101/327064 — genomics — Posted on 2019-04-19

1045 A machine-learning approach for accurate detection of copy-number variants from exome sequencing

Pounraja, V. K.; Jensen, M.; Jayakar, G.; Kelkar, N.; Girirajan, S.

10.1101/460931 — genomics — Posted on 2019-04-19

1046 Engineered Retroviruses as Fluorescent Biological Reference Particles for Nanoscale Flow Cytometry

Tang, V. A.; Fritzsche, A. K.; Renner, T. M.; Burger, D.; Lannigan, J. A.; Brittain, G. C.; Ouellet, C. V.; van der Pol, E.; Langlois, M.-A.

10.1101/614461 — cell biology — Posted on 2019-04-19

1047 Threat-Induced Anxiety During Goal Pursuit Disrupts Amygdala-Prefrontal Cortex Connectivity in Posttraumatic Stress Disorder

Sun, D.; Gold, A.; Swanson, C.; Haswell, C.; Brown, V.; Stjepanovic, D.; VA Mid-Atlantic MIRECC Workgroup, ; LaBar, K.; Morey, R.

10.1101/614446 — neuroscience — Posted on 2019-04-19

1048 Learning optimal decisions with confidence

Drugowitsch, J.; Mendonca, A.; Mainen, Z.; Pouget, A.

10.1101/244269 — neuroscience — Posted on 2019-04-19

1049 Macrophage plasticity is Rac signalling and MMP9 dependant

TRAVNICKOVA, J.; Nhim, S.; ABDELLAOUI, N.; DJOUAD, F.; NGUYEN-CHI, M.; PARMEGGIANI, A.; KISSA, K.

10.1101/614388 — cell biology — Posted on 2019-04-19

1050 Consensus Development Of A Modern Ontology Of Emergency Department Presenting Problems: The HierArchical Presenting Problem OntologY (HaPPy)

Horng, S.; Greenbaum, N.; Nathanson, L. A.; McClay, J.; Goss, F. R.; Nielson, J. A.

10.1101/126870 — bioinformatics — Posted on 2019-04-19

1051 Creating reproducible pharmacogenomic analysis pipelines

Mammoliti, A.; Smirnov, P.; Safikhani, Z.; Ba-Alawi, W.; Haibe-Kains, B.

10.1101/614560 — bioinformatics — Posted on 2019-04-19

1052 Response of Bat Activity to Land-Cover and Land-Use Change in Savannas is Scale-, Season-, and Guild-Specific

Shapiro, J. T.; Monadjem, A.; Roder, T.; McCleery, R.

10.1101/613943 — ecology — Posted on 2019-04-19

1053 Slow and ad hoc: Unravelling the two features characterizing the development of bacterial resistance to membrane active peptides

Majumder, A.; Prakash, M. K.

10.1101/614370 — biophysics — Posted on 2019-04-19

1054 The molecular mechanism of Hsp90-induced oligomerization of Tau

Weickert, S.; Wawrzyniuk, M.; John, L.; Rüdiger, S. G. D.; Drescher, M.

10.1101/614289 — biophysics — Posted on 2019-04-19

1055 Hallmarks of slow translation initiation revealed in mitochondrially localizing mRNA sequences

Poulsen, T. M.; Imai, K.; Frith, M. C.; Horton, P.

10.1101/614255 — molecular biology — Posted on 2019-04-19

1056 GWAS of brain volume on 54,407 individuals and cross-trait analysis with intelligence identifies shared genomic loci and genes

Jansen, P. R.; Nagel, M.; Watanabe, K.; Wei, Y.; Savage, J. E.; de Leeuw, C. A.; van den Heuvel, M.; van der Sluis, S.; Posthuma, D.

10.1101/613489 — genetics — Posted on 2019-04-19

1057 Testing the predictability of morphological evolution in naturally warmed stickleback populations

Pilakouta, N.; Humble, J. L.; Hill, I. D. C.; Kristjansson, B. K.; Skulason, S.; Killen, S. S.; Lindstrom, J.; Metcalfe, N. B.; Parsons, K. J.

10.1101/609933 — evolutionary biology — Posted on 2019-04-19

1058 Organization of Associating or Crosslinked Actin Filaments in Confinement

Adeli Koudehi, M.; Vavylonis, D.

10.1101/614354 — biophysics — Posted on 2019-04-19

1059 Iron Is a Physiological Ligand of SecA-like Metal Binding Domains

Cranford Smith, T.; Jamshad, M.; Jeeves, M.; Alanazi, M.; Carter, C.; Lovett, J. E.; Knowles, T.; Huber, D.

10.1101/613315 — biochemistry — Posted on 2019-04-19

1060 Role of human induced pluripotent stem cell-derived spinal cord astrocytes in the functional maturation of motor neurons in a multielectrode array system

Taga, A.; Dastgheyb, R.; Habela, C.; Joseph, J.; Richard, J.-P.; Gross, S. K.; Lauria, G.; Lee, G.; Haughey, N.; Maragakis, N. J.

10.1101/614297 — neuroscience — Posted on 2019-04-19

1061 Investigation of betaine as a novel psychotherapeutic for schizophrenia

Ohnishi, T.; Balan, S.; Toyoshima, M.; Maekawa, M.; Ohba, H.; Watanabe, A.; Iwayama, Y.; Shimamoto-Mitsuyama, C.; Nozaki, Y.; Hisano, Y.; Esaki, K.; Nagaoka, A.; Matsumoto, J.; Hino, M.; Mataga, N.; Hayashi-Takagi, A.; Kunii, Y.; Kakita, A.; Yabe, H.; Yoshikawa, T.

10.1101/614164 — neuroscience — Posted on 2019-04-19

1062 Scalable, FACS-Free Genome-Wide Phenotypic Screening

Mair, B.; Aldridge, P. M.; Atwal, R. S.; Masud, S. N.; Zhang, M.; Philpott, D.; Tong, A. H. Y.; Sargent, E. H.; Angers, S.; Moffat, J.; Kelley, S. O.

10.1101/612887 — genomics — Posted on 2019-04-19

1063 Leveraging Endogenous ADAR for Programmable Editing on RNA

Qu, L.; Yi, Z.; Zhu, S.; Wang, C.; Cao, Z.; Zhou, Z.; Yuan, P.; Yu, Y.; Tian, F.; Liu, Z.; Bao, Y.; Zhao, Y.; Wei, W.

10.1101/605972 — genomics — Posted on 2019-04-19

1064 Modeling the Language of Life - Deep Learning Protein Sequences

Heinzinger, M.; Elnaggar, A.; Wang, Y.; Dallago, C.; Nachaev, D.; Matthes, F.; Rost, B.

10.1101/614313 — bioinformatics — Posted on 2019-04-19

1065 Modeling of yield Losses and risk analysis of fungicide profitability for managing Fusarium Head Blight in Brazilian spring wheat

Duffeck, M. R.; Alves, K. S.; Machado, F. J.; Esker, P. D.; Del Ponte, E. M.

10.1101/608489 — plant biology — Posted on 2019-04-19

1066 Low Dose Ionizing Radiation Strongly Stimulates Insertional Mutagenesis in a γH2AX Dependent Manner

Zelensky, A. N.; Schoonakker, M.; Brandsma, I.; Tijsterman, M.; van Gent, D. C.; Essers, J.; Kanaar, R.

10.1101/614040 — molecular biology — Posted on 2019-04-19

1067 A Rab GTPase protein FvSec4 is necessary for fumonisin B1 biosynthesis and virulence in Fusarium verticillioides

Yan, H.; Huang, J.; Zhang, H.; Shim, W. B.

10.1101/614206 — microbiology — Posted on 2019-04-19

1068 Structural characterization of the PCV2d genotype at 3.3 A resolution reveals differences to PCV2a and PCV2b genotypes, a tetranucleotide, and an N-terminus near the icosahedral 3-fold axes

Khayat, R.; Wen, K.; Alimova, A.; Gavrilov, B.; Katz, A.; Galarza, J. M.; Gottlieb, P.

10.1101/614198 — biophysics — Posted on 2019-04-19

1069 The role of diffusion and perivascular spaces in dynamic susceptibility contrast MRI

Doucette, J.; Kames, C.; Hernandez-Torres, E.; Traboulsee, A.; Rauscher, A.

10.1101/614008 — biophysics — Posted on 2019-04-19

1070 In vitro evaluation of factor IX as novel treatment for factor XI deficiency

Bakhtiari, K.; Meijers, J. C. M.

10.1101/614180 — biochemistry — Posted on 2019-04-19

1071 Alzheimer’s patient brain myeloid cells exhibit enhanced aging and unique transcriptional activation

Srinivasan, K.; Friedman, B. A.; Etxeberria, A.; Huntley, M. A.; van der Brug, M. P.; Foreman, O.; Paw, J. S.; Modrusan, Z.; Beach, T.; Serrano, G.; Hansen, D.

10.1101/610345 — neuroscience — Posted on 2019-04-19

1072 Data-driven models reveal the organization of diverse cognitive functions in the brain

Nakai, T.; Nishimoto, S.

10.1101/614081 — neuroscience — Posted on 2019-04-19

1073 Overcoming tissue scattering in wide-field deep imaging by extended detection and computational reconstruction

ZHANG, Y.; ZHOU, T.; HU, X.; XIE, H.; FANG, L.; DAI, Q.; KONG, L.

10.1101/611038 — neuroscience — Posted on 2019-04-19

1074 Molecular signatures of non-typeable Haemophilus influenzae lung adaptation in paediatric chronic lung disease

Aziz, A.; Sarovich, D. S.; Nosworthy, E.; Beissbarth, J.; Chang, A.; Smith-Vaughan, H.; Price, E. P.; Harris, T. M.

10.1101/614214 — microbiology — Posted on 2019-04-19

1075 CXCL5-mediated recruitment of neutrophils into the peritoneal cavity of Gdf15-deficient mice protects against abdominal sepsis

Santos, I.; Colaco, H. G.; Neves-Costa, A.; Seixas, E.; Velho, T. R.; Pedroso, D.; Barros, A.; Martins, R.; Weiss, S.; Payen, D.; Weiss, S.; Yi, H.-S.; Shong, M.; Moita, L. F.

10.1101/613901 — immunology — Posted on 2019-04-19

1076 Engineering acetyl-CoA metabolic shortcut for eco-friendly production of polyketides triacetic acid lactone in Yarrowia lipolytica

Liu, H.; Marsafari, M.; Wang, F.; Deng, L.; Xu, P.

10.1101/614131 — bioengineering — Posted on 2019-04-19

1077 Compartmental Modeling Software: a fast, discrete stochastic framework for biochemical and epidemiological simulation

Lorton, C. W.; Proctor, J. L.; Roh, M. K.; Welkhoff, P. A.

10.1101/609172 — epidemiology — Posted on 2019-04-19

1078 Multiplex serologic testing within a cross-sectional lymphatic filariasis sentinel site survey in coastal Kenya reveals community-level differences in IgG antibody responses to parasitic diseases and vaccines

Njenga, S. M.; Kanyi, H. M.; Arnold, B. F.; Matendechero, H. S.; Onsongo, J. K.; Won, K. Y.; Priest, J. W.

10.1101/604181 — epidemiology — Posted on 2019-04-19

1079 Sex and racial differences in cardiovascular disease risk in patients with atrial fibrillation

O'Neal, W. T.; Alam, A. B.; Sandesara, P. B.; Claxton, J. S.; MacLehose, R. F.; Chen, L. Y.; Bengtson, L. G. S.; Chamberlain, A. M.; Norby, F. L.; Lutsey, P. L.; Alonso, A.

10.1101/610352 — epidemiology — Posted on 2019-04-19

1080 Status of Soil-transmitted helminthiasis among pregnant women attending antenatal clinic in Kilifi county hospital, Kenya

Njeru, A.; Mutuku, F.; Muriu, S.

10.1101/613570 — epidemiology — Posted on 2019-04-19

1081 Respiratory disease and lower pulmonary function as risk factors for subsequent dementia: a systematic review with meta-analysis

Russ, T. C.; Kivimaki, M.; Batty, G. D.

10.1101/602193 — epidemiology — Posted on 2019-04-19

1082 After the Honeymoon, the Divorce: Unexpected Outcomes of Disease Control Measures Against Endemic Infections

Hollingsworth, B.; Okamoto, K.; Lloyd, A.

10.1101/608653 — epidemiology — Posted on 2019-04-19

1083 Cohort Profile: HealthWise Wales. A research register and data collection and analysis platform with linkage to NHS datasets in Wales

Hurt, L.; Ashfield-Watt, P.; Townson, J.; Heslop, L.; Copeland, L.; Atkinson, M.; Horton, J.; Paranjothy, S.

10.1101/613547 — epidemiology — Posted on 2019-04-19

1084 Surveillance based dynamic empirical therapy in a health care facility: an artificial intelligence approach

Houy, N.; Flaig, J.

10.1101/611210 — epidemiology — Posted on 2019-04-19

1085 Adverse childhood experiences: associations with educational attainment and adolescent health, and the role of family and socioeconomic factors. Analysis of a prospective cohort study.

Houtepen, L.; Heron, J.; Suderman, M.; Fraser, A.; Chittleborough, C. R.; Howe, L.

10.1101/612390 — epidemiology — Posted on 2019-04-19

1086 Lifestyle and biological factors influence the relation between mental health and low-grade inflammation

Gialluisi, A.; Bonaccio, M.; Di Castelnuovo, A.; Costanzo, S.; De Curtis, A.; Sarchiapone, M.; Cerletti, C.; Donati, M. B.; de Gaetano, G.; Iacoviello, L.; The Moli-sani Study Investigators,

10.1101/609768 — epidemiology — Posted on 2019-04-19

1087 Changes in historical typhoid transmission across 16 U.S. cities, 1889-1931: Quantifying the impact of investments in water and sewer infrastructures

Phillips, M. T.; Owers, K. A.; Grenfell, B. T.; Pitzer, V. E.

10.1101/609677 — epidemiology — Posted on 2019-04-19

1088 Is disrupted sleep a risk factor for Alzheimers disease? Evidence from a two-sample Mendelian randomization analysis

Anderson, E. L.; Richmond, R. C.; Jones, S. E.; Hemani, G.; Wade, K. H.; Dashti, H. S.; Lane, J. M.; Wang, H.; Saxena, R.; Brumpton, B.; Korologou-Linden, R.; Nielsen, J. B.; Asvold, B. O.; Abecasis, G.; Coulthard, E.; Kyle, S. D.; Beaumont, R. N.; Tyrrell, J.; Frayling, T. M.; Munafo, M. R.; Wood, A. R.; Ben-Shlomo, Y.; Howe, L. D.; Lawlor, D. A.; Weedon, M. N.; Davey Smith, G.

10.1101/609834 — epidemiology — Posted on 2019-04-19

1089 Differential serological diagnostics of different Rabbit Haemorrhagic Disease Viruses co-circulating in Australia

Strive, T.; Piper, M.; Huang, N.; Mourant, R.; Kovaliski, J.; Capucci, L.; Cox, T. E.; Smith, I.

10.1101/613158 — epidemiology — Posted on 2019-04-19

1090 Modeling in an oral health study through two statisticalmethods in Uruguay

Alvarez Vaz, R.; Massa, F.; Berberian, N.

10.1101/611921 — epidemiology — Posted on 2019-04-19

1091 Optimizing oleaginous yeast cell factories for flavonoids and hydroxylated flavonoids biosynthesis

Lv, Y.; Koffas, M.; Zhou, J.; Xu, P.

10.1101/614099 — synthetic biology — Posted on 2019-04-19

1092 Spatiotemporal restriction of FUSCA3 expression by class I BPC promotes ovule development and coordinates embryo and endosperm growth

Gazzarrini, S.; Wu, J.; Gregis, V.; Petrella, R.; Dowhanik, S.

10.1101/612408 — plant biology — Posted on 2019-04-19

1093 Age, Sex, and Genetics Influence the Abundance of Infiltrating Immune Cells in Human Tissues

Marderstein, A. R.; Uppal, M.; Verma, A.; Bhinder, B.; Mezey, J.; Clark, A. G.; Elemento, O.

10.1101/614305 — genetics — Posted on 2019-04-19

1094 Lapses in perceptual judgments reflect exploration

Pisupati, S.; Chartarifsky-Lynn, L.; Khanal, A.; Churchland, A. K.

10.1101/613828 — neuroscience — Posted on 2019-04-19

1095 Genetic control of variability in subcortical and intracranial volumes

Cordova-Palomera, A.; Meer, D. v. d.; Kaufmann, T.; Bettella, F.; Wang, Y.; Alnaes, D.; Doan, N. T.; Agartz, I.; Bertolino, A.; Buitelaar, J. K.; Coynel, D.; Djurovic, S.; Dorum, E. S.; Espeseth, T.; Fazio, L.; Franke, B.; Frei, O.; Haberg, A.; Le Hellard, S.; Jonsson, E. G.; Kolskar, K. K.; Lund, M. J.; Moberget, T.; Nordvik, J. E.; Nyberg, L.; Papassotiropoulos, A.; Pergola, G.; de Quervain, D.; Rampino, A.; Richard, G.; Rokicki, J.; Sanders, A.-M.; Schwarz, E.; Smeland, O. B.; Steen, V. M.; Starrfelt, J.; Sonderby, I. E.; Ulrichsen, K. M.; Andreassen, O. A.; Westlye, L. T.

10.1101/443549 — neuroscience — Posted on 2019-04-19

1096 The proteome of Tetrasphaera elongata is adapted to changing conditions in wastewater treatment plants

Herbst, F.-A.; Dueholm, M. S.; Wimmer, R.; Nielsen, P. H.

10.1101/513143 — microbiology — Posted on 2019-04-19

1097 Polymer coil-globule phase transition is a universal folding principle of Drosophila epigenetic domains

Lesage, A.; Dahirel, V.; Victor, J.-M.; Barbi, M.

10.1101/383158 — biophysics — Posted on 2019-04-19

1098 Frequent Non-random Shifts in the Temporal Sequence of Developmental Landmark Events during Teleost Evolutionary Diversification

Ito, F.; Matsumoto, T.; Hirata, T.

10.1101/239954 — evolutionary biology — Posted on 2019-04-19

1099 Elav-mediated exon skipping and alternative polyadenylation of the Dscam1 gene is required for axon outgrowth

Zhang, Z.; So, K.; Peterson, R.; Bauer, M.; Ng, H.; Zhang, Y.; Kim, J. H.; Kidd, T.; Miura, P.

10.1101/613059 — molecular biology — Posted on 2019-04-19

1100 The reverse TCA cycle and reductive amino acid synthesis pathways contribute to electron balance in a Rhodospirillum rubrum Calvin cycle mutant

McCully, A. L.; Onyeziri, M. C.; LaSarre, B.; Gliessman, J. R.; McKinlay, J. B.

10.1101/614065 — microbiology — Posted on 2019-04-19

1101 Two-Color Spatial Cumulant Analysis Detects Heteromeric Interactions between Membrane Proteins

Foust, D. J.; Godin, A. G.; Ustione, A.; Wiseman, P. W.; Piston, D. W.

10.1101/613927 — biophysics — Posted on 2019-04-19

1102 Rapid 3D enhanced resolution microscopy reveals the dynamics of cortical dendritic spinules

Zaccard, C. R.; Myczek, K.; Martin-de-Saavedra, M. D.; Penzes, P.

10.1101/613992 — neuroscience — Posted on 2019-04-18

1103 On the efficacy of restoration in stream networks: comment and critique

Murray-Stoker, D.

10.1101/611939 — ecology — Posted on 2019-04-18

1104 Automated analysis of large-scale NMR data generates metabolomic signatures and links them to candidate metabolites

Khalili, B.; Tomasoni, M.; Mattei, M.; Mallol Parera, R.; Sonmez, R.; Krefl, D.; Rueedi, R.; Bergmann, S.

10.1101/613935 — bioinformatics — Posted on 2019-04-18

1105 Single cell multi-modal analysis with VDJPuzzle identifies clonality and gene expression profiles of T and B cells

Samir, J.; Rizzetto, S.; Gupta, M.; Singh, M.; Jackson, K. J.; Cai, C.; Eltahla, A.; Bull, R. A.; Reed, J. H.; Goodnow, C.; Luciani, F.

10.1101/613083 — bioinformatics — Posted on 2019-04-18

1106 A High Dose Tango Intervention for People with Parkinson’s disease (PwPD)

Rabinovich, D. B.; Garreto, N.; Arakaki, T.; DeSouza, J. F.

10.1101/613661 — neuroscience — Posted on 2019-04-18

1107 Somatic Genetic Aberrations in Benign Breast Disease and the Risk of Subsequent Breast Cancer

Zeng, Z.; Vo, A.; Li, X.; Shidfar, A.; Saldana, P.; Xuei, X.; Luo, Y.; Khan, S. A.; Clare, S. E.

10.1101/613505 — genetics — Posted on 2019-04-18

1108 The genetic architecture of Parkinson disease in Spain: characterizing population-specific risk, differential haplotype structures, and providing etiologic insight

Bandres Ciga, S.; Ahmed, S.; Sabir, M.; Blauwendraat, C.; Adarmes-Gomez, A.; Bernal-Bernal, I.; Bonilla-Toribio, M.; Buiza-Rueda, D.; Carrillo, F.; Carrion-Claro, M.; Gomez-Garre, P.; Jesus, S.; Labrador-Espinosa, M. A.; Macias, D.; Mendez-del-Barrio, C.; Perinan-Tocino, T.; Tejera-Parrado, C.; Vargas-Gonzalez, L.; Diez-Fairen, M.; Alvarez, I.; Tartari, J. P.; Buongiorno, M. T.; Aguilar, M.; Gorostidi, A.; Bergareche, J. A.; Mondragon, E.; Ruiz-Martinez, J.; Dols-Icardo, O.; Kulisevsky, J.; Marin-Lahoz, J.; Pagonabarraga, J.; Pascual-Sedano, B.; Ezquerra, M.; Camara, A.; Compta, Y.; Fernandez,

10.1101/609016 — neuroscience — Posted on 2019-04-18

1109 A chemical interpretation of protein electron density maps in the worldwide protein data bank

Yao, S.; Moseley, H. N. B.

10.1101/613109 — molecular biology — Posted on 2019-04-18

1110 Phylogenomics resolves major relationships and reveals significant diversification rate shifts in the evolution of silk moths and relatives

Hamilton, C. A.; St Laurent, R. A.; Dexter, K.; Kitching, I. J.; Breinholt, J. W.; Zwick, A.; Timmermans, M.; Barber, J. R.; Kawahara, A. Y.

10.1101/517995 — evolutionary biology — Posted on 2019-04-18

1111 A framework for the modular and combinatorial assembly of synthetic gene circuits

Santos-Moreno, J.; Schaerli, Y.

10.1101/611574 — synthetic biology — Posted on 2019-04-18

1112 Automated analysis of whole brain vasculature using machine learning

Todorov, M. I.; Paetzold, J. C.; Schoppe, O.; Tetteh, G.; Efremov, V.; Voelgyi, K.; Duering, M.; Dichgans, M.; Piraud, M.; Menze, B.; Erturk, A.

10.1101/613257 — neuroscience — Posted on 2019-04-18

1113 The genome of the endangered dryas monkey provides new insights into the evolutionary history of the vervets

van der Valk, T.; Gonda, C. M.; Hart, J.; Hart, T.; Detwiler, K.; Guschanski, K.

10.1101/613273 — genomics — Posted on 2019-04-18

1114 Pharmacological manipulations of judgement bias: a systematic review and meta-analysis

Neville, V.; Nakagawa, S.; Zidar, J.; Paul, E. S.; Lagisz, M.; Bateson, M.; Lovlie, H.; Mendl, M.

10.1101/612382 — animal behavior and cognition — Posted on 2019-04-18

1115 Power, positive predictive value, and sample size calculations for random field theory-based fMRI inference

Ostwald, D.; Schneider, S.; Bruckner, R.; Horvath, L.

10.1101/613331 — neuroscience — Posted on 2019-04-18

1116 A glycosaminoglycan extract from Portunus pelagicus inhibits BACE1, the β secretase implicated in Alzheimer’s disease

Mycroft-West, C.; Cooper, L.; Devlin, A.; Procter, P.; Guimond, S.; Guerrini, M.; Fernig, D.; Lima, M.; Yates, E.; Skidmore, M.

10.1101/613695 — biochemistry — Posted on 2019-04-18

1117 Discovery of functional alternatively spliced PKM transcripts in human cancers

Li, X.; Zhang, C.; Kim, W.; Arif, M.; Gao, C.; Hober, A.; Kotol, D.; Strandberg, L.; Forsstrom, B.; Sivertsson, A.; Oksvold, P.; Grotli, M.; Sato, Y.; Kume, H.; Ogawa, S.; Boren, J.; Nielsen, J.; Uhlen, M.; Mardinolgu, A.

10.1101/613364 — systems biology — Posted on 2019-04-18

1118 The Coxiella burnetii secreted protein kinase CstK influences vacuole development and interacts with the GTPase-activating protein TBC1D5

Brelle, S.; Martinez, E.; Huc-Brandt, S.; Allombert, J.; Cantet, F.; Gannoun-Zaki, L.; Letourneur, F.; Bonazzi, M.; Molle, V.

10.1101/611707 — microbiology — Posted on 2019-04-18

1119 Diversity begets diversity in microbiomes

Madi, N. J.; Vos, M.; Legendre, P.; Shapiro, B. J.

10.1101/612739 — evolutionary biology — Posted on 2019-04-18

1120 Population differences in aggression are shaped by cyclone-induced selection

Little, A. G.; Fisher, D. N.; Schoener, T.; Pruitt, J. N.

10.1101/612838 — ecology — Posted on 2019-04-18

1121 Combined behavioral and electrophysiological evidence for a direct cortical effect of prefrontal tDCS on disorders of consciousness

Hermann, B.; Raimondo, F.; Hirsch, L. A.; Huang, Y.; Denis-Valente, M.; Perez, P.; Engemann, D.-A.; Faugeras, F.; Weiss, N.; Demeret, S.; Rohaut, B.; Parra, L. C.; Sitt, J. D.; Naccache, L.

10.1101/612309 — neuroscience — Posted on 2019-04-18

1122 Sensorimotor peak alpha frequency is a reliable biomarker of pain sensitivity

Furman, A. J.; Prokhorenko, M.; Keaser, M. L.; Zhang, J.; Mazaheri, A.; Seminowicz, D.

10.1101/613299 — neuroscience — Posted on 2019-04-18

1123 GABA-mediated tonic inhibition differentially modulates gain in functional subtypes of cortical interneurons

Bryson, A.; Hatch, R.; Zandt, B.-J.; Rossert, C.; Berkovic, S.; Reid, C. A.; Grayden, D. B.; Hill, S.; Petrou, S.

10.1101/613075 — neuroscience — Posted on 2019-04-18

1124 Maternal antibodies provide partial protection from postnatal Zika viremia in nonhuman primates

Maness, N.; Schouest, B.; Singapuri, A.; Dennis, M.; Gilbert, M.; Bohm, R.; Schiro, F.; Aye, P.; Baker, K.; Van Rompay, K.; Lackner, A.; Bonaldo, M.; Blair, R.; Permar, S.; Coffey, L.; Panganiban, A.; Magnani, D.

10.1101/612754 — microbiology — Posted on 2019-04-18

1125 baerhunter: An R package for the discovery and analysis of expressed non-coding regions in bacterial RNA-seq data

Ozuna, A.; Liberto, D.; Joyce, R. M.; Arnvig, K. B.; Nobeli, I.

10.1101/612937 — bioinformatics — Posted on 2019-04-18

1126 Individual structural features constrain the functional connectome

Melozzi, F.; Bergmann, E.; Harris, J. A.; Kahn, I.; Jirsa, V.; Bernard, C.

10.1101/613307 — neuroscience — Posted on 2019-04-18

1127 Cross-modal integration of reward value during oculomotor planning

Cheng, F. P.-H.; Saglam, A.; Andre, S.; Pooresmaeili, A.

10.1101/613349 — neuroscience — Posted on 2019-04-18

1128 Determination of clinical risk factors associated with inflammation in hypertensive patients with type-2 diabetes mellitus

Ellulu, M. S.

10.1101/613711 — epidemiology — Posted on 2019-04-18

1129 Induction of Rare Conformation of Oligosaccharide by Binding to Calcium-dependent Bacterial Lectin: X-ray Crystallography and Modelling Study

Lepsik, M.; Sommer, R.; Kuhaudomlarp, S.; Lelimousin, M.; Paci, E.; Varrot, A.; Titz, A.; Imberty, A.

10.1101/612689 — biophysics — Posted on 2019-04-18

1130 Integration of a Computational Pipeline for Dynamic Inference of Gene Regulatory Networks in Single Cells

Ko, K. D.; Dell'Orso, S.; Juan, A. H.; Sartorelli, V.

10.1101/612952 — bioinformatics — Posted on 2019-04-18

1131 Single-cell analysis of a mutant library generated using CRISPR-guided deaminase

Jun, S.; Lim, H.; Lee, J. H.; Bang, D.

10.1101/610725 — bioengineering — Posted on 2019-04-18

1132 Optimal Mass Transport Kinetic Modeling for Head and Neck DCE-MRI: Initial Analysis

Elkin, R.; Nadeem, S.; LoCastro, E.; Paudyal, R.; Shukla-Dave, A.; Lee, N. Y.; Deasy, J. O.; Tannenbaum, A.

10.1101/612770 — systems biology — Posted on 2019-04-18

1133 A multi-omic analysis of optineurin proteinopathy in a yeast model suggests the involvement of lipid metabolism in Amyotrophic Lateral Sclerosis

Bean, D. M.; Hntova, S.; Muelleder, M.; Magalhaes, S.; Nightingale, D. J. H.; Lilley, K. S.; Ralser, M.; Nunes, A.; Goodfellow, B. J.; Oliver, S. G.

10.1101/605998 — systems biology — Posted on 2019-04-18

1134 Biologically plausible learning in a deep recurrent spiking network

Rotermund, D.; Pawelzik, K. R.

10.1101/613471 — neuroscience — Posted on 2019-04-18

1135 Genomic profiling of Nitrospira species reveals ecological success of comammox Nitrospira

Palomo, A.; Dechesne, A.; Smets, B. F.

10.1101/612226 — microbiology — Posted on 2019-04-18

1136 Comparative analysis of gene expression in virulent and attenuated strains of infectious bronchitis virus at sub-codon resolution

Dinan, A. M.; Keep, S.; Bickerton, E.; Britton, P.; Firth, A. E.; Brierley, I.

10.1101/612614 — genomics — Posted on 2019-04-18

1137 Haplotype-based genome wide association study using a novel SNP-set method : RAINBOW

Hamazaki, K.; Iwata, H.

10.1101/612028 — genetics — Posted on 2019-04-18

1138 Vinculin anchors contractile actin to the cardiomyocyte adherens junction

Merkel, C. D.; Li, Y.; Raza, Q.; Stolz, D. B.; Kwiatkowski, A.

10.1101/613455 — cell biology — Posted on 2019-04-18

1139 Nerve Excitability Differences in Slow and Fast Motor Axons of the Rat: more than just Ih

Bell, J. M.; Lorenz, C.; Jones, K. E.

10.1101/613984 — neuroscience — Posted on 2019-04-18

1140 Dynamic Response in the Larval Geoduck Clam Proteome to Elevated pCO2

Timmins-Schiffman, E. B.; Guzman, J.; Elliott, R.; Vadopalas, B.; Roberts, S. B.

10.1101/613018 — molecular biology — Posted on 2019-04-18

1141 A novel reporter gene assay for pyrogen detection

He, Q.; Yu, F. C.; Wang, L.; Ni, B. Y.; Zhang, H.; Du, Y.; Gao, H.; Wang, Z. J.

10.1101/613190 — immunology — Posted on 2019-04-18

1142 The impact of population variation in the analysis of microRNA target sites

Helmy, M.; Hatlen, A.; Marco, A.

10.1101/613380 — evolutionary biology — Posted on 2019-04-18

1143 A CRISPR Knockout Screen Identifies Foxf1 as a Suppressor of Colorectal Cancer Metastasis That Acts Through Reduced mTOR Signalling

Lee, L. Y.; Woolley, C.; Starkey, T.; Freeman-Mills, L.; Bassett, A.; Franchini, F.; Wang, L. M.; Lewis, A. J.; Arnold, R.; Tomlinson, I.

10.1101/613356 — cancer biology — Posted on 2019-04-18

1144 Raven Calls Indicate Sender’s Neural State

Huang, Z.; Wang, Z.; XIE, J.; Mirt, G.; YAN, C.; Zhong, J.; Deng, X.; LIU, F.; ZHOU, C.; XU, F.

10.1101/613778 — bioengineering — Posted on 2019-04-18

1145 Experience-dependent coding of frequency-modulated trajectories by offsets in auditory cortex

Chong, K. K.; Dunlap, A. G.; Kacsoh, D. B.; Liu, R. C.

10.1101/613448 — neuroscience — Posted on 2019-04-18

1146 Action kinematics as an organising principle in the cortical control of human hand movement

Kolasinski, J.; Dima, D. C.; Mehler, D. M. A.; Stevenson, A.; Valadan, S.; Kusmia, S.; Rossiter, H. E.

10.1101/613323 — neuroscience — Posted on 2019-04-18

1147 Sustained dechlorination of vinyl chloride to ethene in Dehalococcoides-enriched cultures grown without addition of exogenous vitamins and at low pH

Puentes Jacome, L. A.; Wang, P.-H.; Molenda, O.; Li, Y. X.; Islam, M. A.; Edwards, E. A.

10.1101/612242 — microbiology — Posted on 2019-04-18

1148 Legofit: Estimating Population History from Genetic Data

Rogers, A. R.

10.1101/613067 — evolutionary biology — Posted on 2019-04-18

1149 Niche differentiation is spatially and temporally regulated in the rhizosphere

Nuccio, E. E.; Starr, E.; Karaoz, U.; Brodie, E. L.; Zhou, J.; Tringe, S.; Malmstrom, R. R.; Woyke, T.; Banfield, J. F.; Firestone, M. K.; Pett-Ridge, J.

10.1101/611863 — ecology — Posted on 2019-04-18

1150 Predictors of colony extinction vary by habitat type in social spiders

McEwen, B.; Lichstenstein, J.; Fisher, D.; Wright, C.; Chism, G.; Pinter-Wollman, N.; Pruitt, J.

10.1101/612432 — ecology — Posted on 2019-04-18

1151 The cryptic impacts of invasion: functional homogenization of tropical ant communities by invasive fire ants

Wong, M. K.; Guenard, B.; Lewis, O. T.

10.1101/611749 — ecology — Posted on 2019-04-18

1152 Nanoscale subcellular architecture revealed by multicolor 3D salvaged fluorescence imaging

Zhang, Y.; Schroeder, L. K.; Lessard, M. D.; Kidd, P.; Chung, J.; Song, Y.; Benedetti, L.; Li, Y.; Ries, J.; De Camilli, P.; Rothman, J. E.; Baddeley, D.; Bewersdorf, J.

10.1101/613174 — biophysics — Posted on 2019-04-18

1153 Bioinformatics Pipeline using JUDI: Just Do It

Pal, S.; Przytycka, T. M.

10.1101/611764 — bioinformatics — Posted on 2019-04-18

1154 PopTargs: A database for studying population evolutionary genetics of human microRNA target sites

Hatlen, A.; Helmy, M.; Marco, A.

10.1101/613372 — bioinformatics — Posted on 2019-04-18

1155 Microeconomics of metabolism: Overflow metabolism as Giffen behavior

Yamagishi, J. F.; Hatakeyama, T. S.

10.1101/613166 — systems biology — Posted on 2019-04-18

1156 High-fat diet enhances starvation-induced hyperactivity via sensitizing hunger-sensing neurons in Drosophila

Huang, R.; Song, T.; Su, H.; Wang, L.

10.1101/612234 — neuroscience — Posted on 2019-04-18

1157 Single Cortical Neurons as Deep Artificial Neural Networks

Beniaguev, D.; Segev, I.; London, M.

10.1101/613141 — neuroscience — Posted on 2019-04-18

1158 Structure and functional implications of WYL-domain-containing transcription factor PafBC involved in the mycobacterial DNA damage response

Mueller, A. U.; Leibundgut, M.; Ban, N.; Weber-Ban, E.

10.1101/612655 — molecular biology — Posted on 2019-04-18

1159 Translocation of dense granule effectors across the parasitophorous vacuole membrane in Toxoplasma-infected cells requires the activity of ROP17, a rhoptry protein kinase.

Panas, M. W.; Ferrel, A.; Naor, A.; Tenborg, E.; Lorenzi, H. A.; Boothroyd, J. C.

10.1101/613208 — microbiology — Posted on 2019-04-18

1160 Modelling spatial variation in agricultural field trials with INLA

Selle, M. L.; Steinsland, I.; Hickey, J. M.; Gorjanc, G.

10.1101/612036 — genomics — Posted on 2019-04-18

1161 The Positive End of the Polygenic Score Distribution for ADHD: A Risk, Protective or Resilience Factor?

Li, J. J.

10.1101/611897 — genomics — Posted on 2019-04-18

1162 Endogenous RNAi pathway evolutionarily shapes the destiny of the antisense lncRNAs transcriptome

Szachnowski, U.; Andus, S.; Foretek, D.; Morillon, A.; Wery, M.

10.1101/612630 — genomics — Posted on 2019-04-18

1163 Use of latent class analysis to identify multimorbidity patterns and associated factors in Korean adults aged 50 years and older

Park, B.; Lee, H. A.; park, h.

10.1101/613646 — epidemiology — Posted on 2019-04-18

1164 Direct observation of branching MT nucleation in living animal cells.

Verma, V.; Maresca, T. J.

10.1101/613463 — cell biology — Posted on 2019-04-18

1165 K-FIT: An accelerated kinetic parameterization algorithm using steady-state fluxomic data

Gopalakrishnan, S.; Dash, S.; Maranas, C.

10.1101/612994 — systems biology — Posted on 2019-04-18

1166 Prevalence of vitamin D deficiency between Saudis and non-Saudis in Al-Madinah Al-Munawarah region

Nasr, M. H.

10.1101/613729 — pharmacology and toxicology — Posted on 2019-04-18

1167 A pilot Study: Auditory Steady-State Responses (ASSR) can be measured in human Fetuses using fetal Magnetoencephalography (fMEG)

Niepel, D. M.; Krishna, B.; Siegel, E. R.; Draganova, R.; Preissl, H.; Govindan, R. B.; Eswaran, H.

10.1101/610303 — neuroscience — Posted on 2019-04-18

1168 The self-organized learning of noisy environmental stimuli requires distinct phases of plasticity

Krueppel, S.; Tetzlaff, C.

10.1101/612341 — neuroscience — Posted on 2019-04-18

1169 A chromatogram-simplified Streptomyces albus host for heterologous production of natural products

Fazal, A.; Thankachan, D.; Harris, E.; Seipke, R. F.

10.1101/612291 — microbiology — Posted on 2019-04-18

1170 Loss of microbial diversity and body site heterogeneity in individuals with Hidradenitis Suppurativa

Schneider, A. M.; Cook, L. C.; Zhan, X.; Banerjee, K.; Cong, Z.; Imamura Kawasawa, Y.; Gettle, S. L.; Longenecker, A. L.; Kirby, J. S.; Nelson, A. M.

10.1101/612457 — microbiology — Posted on 2019-04-18

1171 HIV-1 controllers exhibit an enhanced antiviral state characterized by overexpression of p21 and MCPIP1

de Azevedo, S. S. D.; Ribeiro-Alves, M.; Cortes, F. H.; Delatorre, E.; Hoagland, B.; Grinsztejn, B.; Veloso, V. G.; Morgado, M. G.; Souza, T. M. L.; Bello, G.

10.1101/611871 — immunology — Posted on 2019-04-18

1172 Social value unblocks Pavlovian reinforcement learning in male rats

van Gurp, S.; Hoog, J.; Kalenscher, T.; van Wingerden, M.

10.1101/612697 — animal behavior and cognition — Posted on 2019-04-18

1173 Meningeal Worm Infection in Central Iowa Goat Herds II: Individual Cases and Treatment Using a Camelid Therapeutic Protocol

Smith, J.; Kreuder, A.; Breuer, R.; Still-Brooks, K.

10.1101/613562 — pharmacology and toxicology — Posted on 2019-04-18

1174 Hippocampal network reorganization underlies the formation of a temporal association memory

Ahmed, M. S.; Priestley, J. B.; Castro, A.; Stefanini, F.; Balough, E. M.; Lavoie, E.; Mazzucato, L.; Fusi, S.; Losonczy, A.

10.1101/613638 — neuroscience — Posted on 2019-04-18

1175 Single-cell analysis of Foxp1-driven mechanisms essential for striatal development

Anderson, A. G.; Kulkarni, A.; Harper, M.; Konopka, G.

10.1101/611780 — neuroscience — Posted on 2019-04-18

1176 Production of high cellulase yields from polypore fungi in solid-state fermentation using green tea waste

Nguyen, A. K.; Penkhrue, W.; Lumyong, S.

10.1101/612093 — microbiology — Posted on 2019-04-18

1177 Dissecting mechanisms of human islet differentiation and maturation through epigenome profiling

Alvarez-Dominguez, J. R.; Donaghey, J.; Kenty, J. H. R.; Rasouli, N.; Helman, A.; Charlton, J.; Straubhaar, J. R.; Meissner, A.; Melton, D. A.

10.1101/613026 — genomics — Posted on 2019-04-18

1178 Clinical and Cost Effectiveness of Two New Lynch Syndrome Case Finding Protocols in Endometrial Cancer Population Contrasted with the IHC-based Protocol

Gudgeon, J. M.; Varner, M. W.; Hashibe, M.; Williams, M. S.

10.1101/611541 — genetics — Posted on 2019-04-18

1179 ChIA-DropBox: a novel analysis and visualization pipeline for multiplex chromatin interactions

Tian, S. Z.; Capurso, D.; Kim, M.; Lee, B.; Zheng, M.; Ruan, Y.

10.1101/613034 — bioinformatics — Posted on 2019-04-18

1180 Pan-genomic and Polymorphic Driven Prediction of Antibiotic Resistance in Elizabethkingia

Naidenov, B. V.; Lim, A.; Willyerd, K.; Torres, N. J.; Johnson, W. L.; Hwang, H. J.; Hoyt, P. R.; Gustafson, J. E.; Chen, C.

10.1101/613877 — bioinformatics — Posted on 2019-04-18

1181 Neural Selectivity, Efficiency, and Dose Equivalence in Deep Brain Stimulation through Pulse Width Tuning and Segmented Electrodes.

Anderson, C. J.; Anderson, D. N.; Pulst, S. M.; Butson, C. R.; Dorval, A. D.

10.1101/613133 — neuroscience — Posted on 2019-04-18

1182 Parallel signatures of mammalian domestication and human industrialization in the gut microbiota

Reese, A.; Chadaideh, K. S.; Diggins, C. E.; Beckel, M.; Callahan, P.; Ryan, R.; Emery Thompson, M.; Carmody, R. N.

10.1101/611483 — microbiology — Posted on 2019-04-18

1183 The Role of fosA in Challenges with Fosfomycin Susceptibility Testing of Multispecies Klebsiella pneumoniae Carbapenemase-Producing Clinical Isolates

Elliott, Z. S.; Barry, K. E.; Cox, H. L.; Stoesser, N.; Carroll, J.; Vegesana, K. B.; Kotay, S. M.; Sheppard, A. E.; Wailan, A. M.; Crook, D. W.; Parikh, H.; Mathers, A. J.

10.1101/611970 — microbiology — Posted on 2019-04-18

1184 Fecal microbiota as a non-invasive biomarker to predict the tissue iron accumulation in intestine epithelial cells and liver

Liu, B.; Pan, X.; Yao, L.; Chen, S.; Liu, Z.; Han, M.; Yin, Y.; Xu, G.; Wan, D.; Dai, X.; Sun, J.; Pan, J.; Zhang, H.; Wang, W.; Liu, L.; Xie, L.

10.1101/612168 — microbiology — Posted on 2019-04-18

1185 Estradiol modulates gut microbiota in female ob/ob mice fed a high fat diet

Acharya, K.; Gao, X.; Bless, E.; Chen, J.; Tetel, M.

10.1101/612283 — microbiology — Posted on 2019-04-18

1186 Environmental variation mediates the evolution of anticipatory parental effects

Lind, M. I.; Zwoinska, M. K.; Andersson, J.; Carlsson, H.; Krieg, T.; Larva, T.; Maklakov, A. A.

10.1101/606103 — evolutionary biology — Posted on 2019-04-18

1187 Epigenetic regulation of unique genes and repetitive elements by the KRAB zinc finger protein ZFP57

Shi, H.; Strogantsev, R.; Takahashi, N.; Kazachenka, A.; Lorincz, M.; Hemberger, M.; Ferguson-Smith, A.

10.1101/611400 — developmental biology — Posted on 2019-04-18

1188 Early urine proteome changes in an implanted bone cancer rat model

Wang, T.; Li, L.; Qin, W.; Huan, Y.; Gao, Y.

10.1101/613125 — cancer biology — Posted on 2019-04-18

1189 Differential network analysis of human tissue interactomes highlights tissue-selective processes and genetic disorder genes

Basha, O.; Argov, C.; Artzy, R.; Zoabi, Y.; Hekselman, I.; Alfandari, L.; Chalifa-Caspi, V.; Yeger-Lotem, E.

10.1101/612143 — bioinformatics — Posted on 2019-04-18

1190 Iterative feature selection method to discover predictive variables and interactions for high-dimensional transplant genomic data

Huang, H.; Vierra-Green, C.; Spellman, S.; Kennedy, C.

10.1101/605428 — bioinformatics — Posted on 2019-04-18

1191 SequelQC: Analyzing PacBio Sequel Raw Sequence Quality

Hufnagel, D. E.; Hufford, M. B.; Seetharam, A. S.

10.1101/611814 — bioinformatics — Posted on 2019-04-18

1192 Comparing and Validating Automated Tools for Individualized Electric Field Simulations in the Human Head

Puonti, O.; Bicalho Saturnino, G.; Madsen, K. H.; Thielscher, A.

10.1101/611962 — bioengineering — Posted on 2019-04-18

1193 Cortical sensitivity to natural scene structure

Kaiser, D.; Haeberle, G.; Cichy, R. M.

10.1101/613885 — neuroscience — Posted on 2019-04-18

1194 Characteristics of respiratory measures in young adults scanned at rest, including systematic changes and \"missed\" respiratory events

Power, J.; Silver, B.; Martin, A.; Jones, R.

10.1101/613851 — neuroscience — Posted on 2019-04-18

1195 The user’s guide to comparative genomics with EnteroBase. Three case studies: micro-clades within Salmonella enterica serovar Agama, ancient and modern populations of Yersinia pestis, and core genomic diversity of all Escherichia

Zhou, Z.; Alikhan, N.-F.; Mohamed, K.; the Agama Study Group, ; Achtman, M.

10.1101/613554 — microbiology — Posted on 2019-04-18

1196 Sex-dependent polygenic effects on the clinical progressions of Alzheimer’s disease

Fan, C. C.; Banks, S. J.; Thompson, W. K.; Chen, C.-H.; McEvoy, L. K.; Tan, C. H.; Kukull, W.; Bennett, D. A.; Farrer, L. A.; Mayeux, R.; Schellenberg, G. D.; Andreassen, O. A.; Desikan, R.; Dale, A. M.

10.1101/613893 — genetics — Posted on 2019-04-18

1197 Regulation of HMGB2 integrates ribosome biogenesis and innate immune responses to DNA

Bianco, C.; Mohr, I.

10.1101/611616 — microbiology — Posted on 2019-04-18

1198 Elimination of HSV-2 infected cells is mediated predominantly by paracrine effects of tissue-resident T cell derived cytokines

Roychoudhury, P.; Swan, D. A.; Duke, E.; Corey, L.; Zhu, J.; Dave, V.; Richert Spuhler, L.; Lund, J. M.; Prlic, M.; Schiffer, J.

10.1101/610634 — immunology — Posted on 2019-04-18

1199 Retinal and callosal activity-dependent chandelier cell elimination shapes binocularity in primary visual cortex

Wang, B.-S.; Bernardez Sarria, M. S.; He, M.; Crair, M. C.; Huang, Z. J.

10.1101/612358 — neuroscience — Posted on 2019-04-18

1200 Butterfly abundance declines over 20 years of systematic monitoring in Ohio, USA

Wepprich, T.; Adrion, J.; Ries, L.; Wiedmann, J.; Haddad, N.

10.1101/613786 — ecology — Posted on 2019-04-18

1201 Shared morphological consequences of global warming in North American migratory birds

Weeks, B. C.; Willard, D. E.; Ellis, A. A.; Witynski, M. L.; Hennen, M.; Winger, B. M.

10.1101/610329 — ecology — Posted on 2019-04-18

1202 Seasonal zonation patterns of the sandy beach bivalve Donax deltoides (Bivalvia: Donacidae) in subtropical eastern Australia

Totterman, S.

10.1101/610576 — ecology — Posted on 2019-04-18

1203 Untangling the Indonesian tangle net fishery: describing a data-poor fishery targeting large threatened rays (Order Batoidea)

D'Alberto, B. M.; White, W. T.; Chin, A.; Dharmadi, D.; Simpfendorfer, C. A.

10.1101/608935 — zoology — Posted on 2019-04-18

1204 Hippocampal theta codes for distances in semantic and temporal spaces

Solomon, E. A.; Lega, B. C.; Sperling, M. R.; Kahana, M. J.

10.1101/611681 — neuroscience — Posted on 2019-04-18

1205 Investigating the role of behaviour in the genetic risk for schizophrenia

Maxwell, J.; Socrates, A.; Glanville, K.; Di Forti, M.; Murray, R.; Vassos, E.; O'Reilly, P.

10.1101/611079 — genetics — Posted on 2019-04-18

1206 Monarch butterfly trends reported in Boyle et al. (2019) are sensitive to unexamined changes in museum collections over time

Wepprich, T. M.

10.1101/562314 — ecology — Posted on 2019-04-18

1207 Phosphatidylserine Exposure after Vascular Injury-Platelet or Endothelial

Agbani, E. O.; Cash, J.; Williams, C.; Poole, A.

10.1101/115139 — physiology — Posted on 2019-04-18

1208 Cortical visual prosthesis: a detailed large-scale simulation study

Antolik, J.; Sabatier, Q.; Galle, C.; Fregnac, Y.; Benosman, R.

10.1101/610378 — neuroscience — Posted on 2019-04-18

1209 Advantages of Multi-shell Diffusion Models for Studies of Brain Development in Youth

Pines, A. R.; Cieslak, M.; Baum, G. L.; Cook, P. A.; Adebimpe, A.; Davila, D. G.; Elliott, M. A.; Jirsaraie, R.; Murtha, K.; Oathes, D. J.; Piiwaa, K.; Rosen, A. F.; Rush, S.; Shinohara, R. T.; Bassett, D. S.; Roalf, D. R.; Satterthwaite, T. D.

10.1101/611590 — neuroscience — Posted on 2019-04-18

1210 A single- nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain

Del-Aguila, J. L.; Li, Z.; Dube, U.; Mihindukulasuriya, K. A.; Budde, J. P.; Fernandez, M. V.; Ibanez, L.; Bradley, J.; Wang, F.; Bergmann, K.; Davenport, R.; Morris, J. C.; Holtzman, D. M.; Perrin, R. J.; Benitez, B. A.; Dougherty, J.; Cruchaga, C.; Harari, O.

10.1101/593756 — genomics — Posted on 2019-04-18

1211 CNCC: An analysis tool to determine genome-wide DNA break end structure at single-nucleotide resolution

Szlachta, K.; Raimer, H.; Comeau, L. D.; Wang, Y.-H.

10.1101/611756 — genomics — Posted on 2019-04-18

1212 The \"amphi\"-brains of amphipods: New insights from the neuroanatomy of Parhyale hawaiensis (Dana, 1853)

Wittfoth, C.; Harzsch, S.; Wolff, C.; Sombke, A.

10.1101/610295 — neuroscience — Posted on 2019-04-18

1213 Meiotic MCM proteins promote and inhibit crossovers during meiotic recombination

Hatkevich, T.; Hartmann, M. A.; Kohl, K. P.; Sekelsky, J.

10.1101/467134 — genetics — Posted on 2019-04-18

1214 Scar-less whole-body regeneration in the absence of a blastema requires cell division in the ctenophore Mnemiopsis leidyi.

Ramon Mateu, J.; Martindale, M. Q.

10.1101/509331 — developmental biology — Posted on 2019-04-18

1215 Methods for Analyzing Imaging Mass Cytometry Data with Tellurium Probes

Bassan, J.; Nitz, M.

10.1101/567685 — bioinformatics — Posted on 2019-04-18

1216 The number sense is an emergent property of a deep convolutional neural network trained for object recognition

DeWind, N. K.

10.1101/609347 — animal behavior and cognition — Posted on 2019-04-18

1217 Multidimensional analysis of extended molecular dynamics simulations shows the complexity of signal transduction by the histamine H3 membrane receptor

Herrera-Zuniga, L. D.; Moreno-Vargas, L. M.; Correa-Basurto, J.; Prada, D.; Curmi, P.; Arrang, J.-M.; Maroun, R. C.

10.1101/604793 — bioinformatics — Posted on 2019-04-18

1218 Spontaneous isomerization of long-lived proteins provides a molecular mechanism for the lysosomal failure observed in Alzheimer’s disease

Lambeth, T.; Riggs, D.; Talbert, L.; Tang, J.; Coburn, E.; Kang, A.; Noll, J.; Augello, C.; Ford, B.; Julian, R.

10.1101/605626 — biochemistry — Posted on 2019-04-18

1219 APOL1-G0 protects podocytes in a mouse model of HIV-associated nephropathy

Bruggeman, L. A.; Wu, Z.; Luo, L.; Madhavan, S.; Drawz, P. E.; Thomas, D. B.; Barisoni, L.; O'Toole, J. F.; Sedor, J. R.

10.1101/598557 — pathology — Posted on 2019-04-18

1220 Tissue and cell-type specific expression of a splice variant in the II-III cytoplasmic loop of Cacna1b

Bunda, A.; LaCarubba, B.; Akiki, M.; Andrade, A.

10.1101/596668 — neuroscience — Posted on 2019-04-18

1221 Specific type 1 diabetes risk genes underpin age-at-diagnosis and indicate joint defects in immunity, beta-cell fragility and responses to viral infections in early-onset disease.

Inshaw, J.; Cutler, A. J.; Crouch, D. J.; Wicker, L. S.; Todd, J. A.

10.1101/577304 — genetics — Posted on 2019-04-18

1222 Towards Quantitative Imaging Biomarkers of Tumor Dissemination: a Multi-scale Parametric Modeling of Multiple Myeloma

Piraud, M.; Wennmann, M.; Kintzele, L.; Hillengass, J.; Keller, U.; Langs, G.; Weber, M.-A.; Menze, B.

10.1101/613869 — bioinformatics — Posted on 2019-04-18

1223 Telomeric small RNAs in the genus Caenorhabditis

Frenk, S.; Lister-Shimauchi, E. H.; Ahmed, S.

10.1101/612820 — genomics — Posted on 2019-04-18

1224 Single-Cell Data Analysis Using MMD VariationalAutoencoder

Zhang, C.

10.1101/613414 — bioinformatics — Posted on 2019-04-18

1225 Exercise enhances motor skill learning by neurotransmitter switching in the adult midbrain

Li, H.-q.; Spitzer, N. C.

10.1101/613539 — neuroscience — Posted on 2019-04-18

1226 Multiple Dynamical Mechanisms of Phase-2 Early Afterdepolarizations in a Human Ventricular Myocyte Model: Involvement of spontaneous SR Ca2+ release

Kurata, Y.; Tsumoto, K.; Hayashi, K.; Hisatome, I.; Kuda, Y.; Tanida, M.

10.1101/613182 — physiology — Posted on 2019-04-18

1227 Phosphatase PP2C6 negatively regulates phosphorylation status of Pti1b kinase, a regulator of flagellin-triggered immunity in tomato

Giska, F.; Martin, G. B.

10.1101/613612 — plant biology — Posted on 2019-04-18

1228 Primary infection with dengue or Zika virus does not affect the severity of heterologous secondary infection in macaques.

Breitbach, M. E.; Newman, C. M.; Dudley, D. M.; Stewart, L. M.; Aliota, M. T.; Koenig, M. R.; Shepherd, P.; Yamamoto, K.; Crooks, C.; Young, G.; Semler, M.; Weiler, A.; Barry, G.; Heimsath, H.; Mohr, E.; Eichoff, J.; Newton, W.; Peterson, E.; Schultz-Darken, N.; Permar, S.; Dean, H.; Capuano, S.; Osorio, J.; Friedrich, T.; O'Connor, D. H.

10.1101/613802 — pathology — Posted on 2019-04-18

1229 Second-generation lung-on-a-chip array with a stretchable biological membrane

Zamprogno, P.; Wuthrich, S.; Achenbach, S.; Stucki, J. D.; Hobi, N.; Schneider-Daum, N.; Lehr, C.-M.; Huwer, H.; Geiser, T.; Schmid, R. A.; Guenat, O. T.

10.1101/608919 — bioengineering — Posted on 2019-04-18

1230 A search for snail-related answers to explain differences in response of Schistosoma mansoni to praziquantel treatment among responding and persistent hotspot villages along the Kenyan shore of Lake Victoria

Mutuku, M.; Laidemitt, M.; Beechler, B. R.; Mwangi, I.; Otiato, F.; Agola, E.; Ochanda, H.; Kamel, B.; Mkoji, G. M.; Steinauer, M. L.; Loker, E. S.

10.1101/394031 — epidemiology — Posted on 2019-04-18

1231 Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug.

Sanderson, L.; da Silva, M.; Sekhar, G. N.; Brown, R. C.; Burrell-Saward, H.; Fidanboylu, M.; Liu, B.; Dailey, L. A.; Dreiss, C. A.; Lorenz, C.; Christie, M.; Persaud, S.; Yardley, V.; Croft, S. L.; Valero, M.; Thomas, S. A.

10.1101/573329 — pharmacology and toxicology — Posted on 2019-04-18

1232 Metrics for Graph Comparison: A Practitioner’s Guide

Wills, P.; Meyer, F. G.

10.1101/611509 — neuroscience — Posted on 2019-04-18

1233 How does genome size affect the evolution of pollen tube growth rate, a haploid performance trait?

Reese, J. B.; Williams, J.

10.1101/462663 — evolutionary biology — Posted on 2019-04-18

1234 A novel deep learning scheme for morphology-based classification of mycobacterial infection in unstained macrophages

Zhao, X.; Bao, Y.; Wang, L.; Qian, W.; Sun, J.

10.1101/611434 — bioengineering — Posted on 2019-04-18

1235 Computational modelling of hippocampal sensitivity to expectation violation

Frank, D.; Montemurro, M.; Montaldi, D.

10.1101/611467 — neuroscience — Posted on 2019-04-18

1236 Domestication of Campylobacter jejuni NCTC 11168

Pascoe, B.; Williams, L. K.; Calland, J. K.; Meric, G.; Hitchings, M. D.; Dyer, M.; Ryder, J.; Shaw, S.; Lopes, B. S.; Chintoan-Uta, C.; Allan, E.; Vidal, A.; Fearnley, C.; Everest, P.; Pachebat, J. A.; Cogan, T. A.; Stevens, M. P.; Humphrey, T. J.; Wilkinson, T. S.; Cody, A. J.; Colles, F. M.; Jolley, K. A.; Maiden, M. C.; Strachan, N.; Pearson, B. M.; Linton, J. D.; Wren, B. W.; Parkhill, J.; Kelly, D. J.; van Vliet, A. H.; Forbes, K. J.; Sheppard, S. K.

10.1101/591701 — microbiology — Posted on 2019-04-18

1237 Polygenic Adaptation has Impacted Multiple Anthropometric Traits

Berg, J. J.; Zhang, X.; Coop, G.

10.1101/167551 — evolutionary biology — Posted on 2019-04-18

1238 Anti-angiogenic effects of VEGF stimulation on endothelium deficient in phosphoinositide recycling

Stratman, A. N.; Farrelly, O. M.; Mikelis, C. M.; Miller, M. F.; Wang, Z.; Pham, V. N.; Davis, A. E.; Burns, M. C.; Pezoa, S. A.; Castranova, D.; Kilts, T. M.; Davis, G. E.; Gutkind, J. S.; Weinstein, B. M.

10.1101/402362 — cell biology — Posted on 2019-04-18

1239 Single-trial neural dynamics are dominated by richly varied movements

Musall, S.; Kaufman, M. T.; Juavinett, A. L.; Gluf, S.; Churchland, A. K.

10.1101/308288 — neuroscience — Posted on 2019-04-18

1240 Modeling implicates inhibitory network bistability as an underpinning of seizure initiation

Rich, S.; Chameh, H. M.; Rafiee, M.; Ferguson, K.; Skinner, F.; Valiante, T.

10.1101/613794 — neuroscience — Posted on 2019-04-18

1241 Complete blood count with differential: An effective diagnostic for IBS subtype in the context of BMI?

Robinson, J.; Boulineaux, C.; Butler, K.; Joseph, P.; Murray, M.; Pocock, S.; Sherwin, L.; Turkington, S.; Weaver, K.; Henderson, W.

10.1101/608208 — immunology — Posted on 2019-04-18

1242 How Cognitive and Affective Empathy Relate to Emotion Regulation: Divergent Patterns from Trait and Task-Based Measures

Thompson, N. M.; van Reekum, C. M.; Chakrabarti, B.

10.1101/611301 — animal behavior and cognition — Posted on 2019-04-18

1243 Factors influencing prevention of mother to child HIV transmission service utilization among HIV positive women in Amhara National Regional State, Ethiopia: A thematic content analysis

Abebe, Z. Z.; Mengistu, M. Y.; Gete, Y. K.; Worku, A. G.

10.1101/613752 — scientific communication and education — Posted on 2019-04-18

1244 A stealth adhesion factor contributes to Vibrio vulnificus pathogenicity: Flp pili play roles in host invasion, survival in the blood stream and resistance to complement activation

Duong-Nu, T.-M.; Jeong, K.; Kim, S. Y.; Tan, W.; Puth, S.; Lee, K. H.; Lee, S. E.; Rhee, J. H.

10.1101/613810 — microbiology — Posted on 2019-04-18

1245 Studying early embryogenesis in the flatworm Maritigrella crozieri indicates a unique modification of the spiral cleavage program in polyclad flatworms

Girstmair, J.; Telford, M. J.

10.1101/610733 — evolutionary biology — Posted on 2019-04-18

1246 Automated Habitat Change Detection Methods using Satellite Data to Improve Conservation Law Implementation

Evans, M. J.; Malcom, J. W.

10.1101/611459 — ecology — Posted on 2019-04-18

1247 Identification of flowering-time genes in mast flowering plants using de novo transcriptomic analysis

Samarth, S.; Lee, R.; Song, J.; Macknight, R.; Jameson, P. E.

10.1101/613745 — plant biology — Posted on 2019-04-18

1248 No evidence for Wolbachia as a nutritional co-obligate endosymbiont in the aphid Pentalonia nigronervosa

Manzano-Marin, A.

10.1101/609511 — genomics — Posted on 2019-04-18

1249 Analyses of rare and common alleles in parent-proband trios implicate rare missense variants in SLC6A1 in schizophrenia and confirm the involvement of loss of function intolerant and neurodevelopmental disorder genes.

Rees, E.; Han, J.; Morgan, J.; Carrera, N.; Escott-Price, V.; Pocklington, A. J.; Duffield, M.; Hall, L.; Legge, S. E.; Pardinas, A. F.; Richards, A. L.; Roth, J.; Lezheiko, T.; Kondratyev, N.; Golimbet, V.; Parellada, M. n.; Gonzalez-Penas, J.; Arango, C.; GROUP Investigators, ; Gawlik, M.; Kirov, G.; Walters, J. T. R.; Holmans, P.; O'Donovan, M. C.; Owen, M. J.

10.1101/607549 — genetics — Posted on 2019-04-18

1250 Droplet-based combinatorial indexing for massive scale single-cell epigenomics

Lareau, C. A.; Duarte, F. M.; Chew, J. G.; Kartha, V. K.; Burkett, Z. D.; Kohlway, A. S.; Pokholok, D.; Aryee, M. J.; Steemers, F. J.; Lebofsky, R.; Buenrostro, J. D.

10.1101/612713 — genomics — Posted on 2019-04-18

1251 In vivo Firre and Dxz4 deletion elucidates roles for autosomal gene regulation

Andergassen, D.; Smith, Z. D.; Lewandowski, J. P.; Gerhardinger, C.; Meissner, A.; Rinn, J. L.

10.1101/612440 — genetics — Posted on 2019-04-18

1252 Butterfly abundance declines over 20 years of systematic monitoring in Ohio, USA

Wepprich, T.; Adrion, J.; Ries, L.; Wiedmann, J.; Haddad, N.

10.1101/613786 — ecology — Posted on 2019-04-18

1253 A study of psychological pain in substance use disorder and its relationship to treatment outcome

Mee, S.; Bunney, B. G.; Fujimoto, K.; Penner, J.; Seward, G.; Bunney, W. E.; Reist, C.

10.1101/613737 — scientific communication and education — Posted on 2019-04-18

1254 Segregated neural explants exhibit co-oriented, asymmetric, neurite outgrowth

Crutcher, K.

10.1101/613703 — neuroscience — Posted on 2019-04-18

1255 Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion

Satpathy, A. T.; Granja, J. M.; Yost, K. E.; Qi, Y.; Meschi, F.; McDermott, G. P.; Olsen, B. N.; Mumbach, M. R.; Pierce, S. E.; Corces, M. R.; Shah, P.; Bell, J. C.; Jhutty, D.; Nemec, C. M.; Wang, J.; Wang, L.; Yin, Y.; Giresi, P. G.; Chang, A. L. S.; Zheng, G. X. Y.; Greenleaf, W. J.; Chang, H. Y.

10.1101/610550 — genomics — Posted on 2019-04-18

1256 The Rising Prevalence of Weapons in Unsafe Arming Configurations Discovered in American Airports: the Increasing Practice of Storage and Carry of Firearms with a Round Chambered

Towers, S.; Amoundi, B.; Cordova, R.; Funderburk, K.; Montalvo, C.; Thakur, M.; Velazquez-Molina, J.; Castillo-Chavez, C.

10.1101/613687 — epidemiology — Posted on 2019-04-18

1257 A Bigenic mouse model of FSGS reveals perturbed pathways in podocytes, mesangial cells and endothelial cells

Potter, A. S.; Drake, K.; Brunskill, E. W.; Potter, S. S.

10.1101/613679 — pathology — Posted on 2019-04-18

1258 GIGANTEA recruits deubiquitylases, UBP12 and UBP13, to regulate accumulation of the ZTL photoreceptor complex

Lee, C.-m.; Li, M. W.; Feke, A.; Saffer, A. M.; Liu, W.; Gendron, J. M.

10.1101/611533 — plant biology — Posted on 2019-04-18

1259 Cell-type specific concentration regulation of the basal transcription factor TFIIH

Donnio, L.-M.; Miquel, C.; Vermeulen, W.; Giglia-Mari, G.; Mari, P.-O.

10.1101/613281 — cell biology — Posted on 2019-04-18

1260 Laminin-driven Epac/Rap1 regulation of epithelial barriers on decellularized matrix

Young, B. M.; Shankar, K.; Tho, C. K.; Pellegrino, A. R.; Heise, R. L.

10.1101/612325 — bioinformatics — Posted on 2019-04-18

1261 Activation of a Protein Kinase Via Asymmetric Allosteric Coupling of Structurally Conserved Signaling Modules

Hao, Y.; England, J. P.; Belluci, L.; Paci, E.; Hodges, H. C.; Taylor, S. S.; Maillard, R. A.

10.1101/611772 — biophysics — Posted on 2019-04-18

1262 Qualitative analyses of polishing and pre-coating FIB milled crystals for MicroED

Martynowycz, M.; Zhao, W.; Hattne, J.; Jensen, G.; Gonen, T.

10.1101/613042 — biochemistry — Posted on 2019-04-18

1263 High specificity of widely used phospho-tau antibodies validated using a quantitative whole-cell based assay

Li, D.; Cho, Y.

10.1101/612911 — biochemistry — Posted on 2019-04-18

1264 Reduced chromatin accessibility underlies gene expression differences in homologous chromosome arms of hexaploid wheat and diploid Aegilops tauschii

Lu, F.-H.; McKenzie, N.; Gardiner, L.-J.; Luo, M.; Hall, A.; Bevan, M. W.

10.1101/571133 — genomics — Posted on 2019-04-18

1265 The more the merrier? Multivariate approaches to genome-wide association analysis

Vroom, C.-R.; de Leeuw, C.; Posthuma, D.; Dolan, C. V.; van der Sluis, S.

10.1101/610287 — genetics — Posted on 2019-04-18

1266 How does genome size affect the evolution of pollen tube growth rate, a haploid performance trait?

Reese, J. B.; Williams, J.

10.1101/462663 — evolutionary biology — Posted on 2019-04-18

1267 Tibanna: software for scalable execution of portable pipelines on the cloud

Lee, S.; Johnson, J.; Vitzthum, C.; Kırlı, K.; Alver, B. H.; Park, P. J.

10.1101/440974 — bioinformatics — Posted on 2019-04-18

1268 A mobile ELF4 delivers circadian temperature information from shoots to roots

Chen, W. W.; Takahashi, N.; Hirata, Y.; Nusinow, D.; Kay, S.; Mas, P.

10.1101/612671 — plant biology — Posted on 2019-04-18

1269 GNI-A1 mediates trade-off between grain number and grain weight in tetraploid wheat

Golan, G.; Ayalon, I.; Perry, A.; Zimran, G.; Ade-Ajayi, T.; Mosquna, A.; Distelfeld, A.; Peleg, Z.

10.1101/540096 — plant biology — Posted on 2019-04-18

1270 Defective photosynthetic adaptation mechanism in winter restricts the introduction of overwintering plant to high latitudes

Li, Y.-N.; Li, Y.-T.; Ivanov, A.; Jiang, W.-L.; Che, X.-K.; Liang, Y.; Zhang, Z.-S.; Zhao, S.-J.; Gao, H.-y.

10.1101/613117 — plant biology — Posted on 2019-04-18

1271 The Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator Fenobam: Pharmacokinetics, Side Effects, and Analgesic Effects in Healthy Human Subjects.

Cavallone, L. F.; Montana, M. C.; Frey, K.; Kallogjeri, D.; Wages, J. M.; Rodebaugh, T. L.; Doshi, T.; Kharasch, E. D.; Gereau, R. W.

10.1101/391383 — neuroscience — Posted on 2019-04-18

1272 Every which way? On predicting tumor evolution using cancer progression models

Diaz-Uriarte, R.; Vasallo, C.

10.1101/371039 — bioinformatics — Posted on 2019-04-18

1273 Lactobacillus rhamnosus Lcr35(R) as an effective treatment for preventing Candida albicans infection in preclinical models: first mechanistical insights

Poupet, C.; Saraoui, T.; Veisseire, P.; Bonnet, M.; Dausset, C.; Gachinat, M.; Camares, O.; Chassard, C.; Nivoliez, A.; Bornes, S.

10.1101/612481 — microbiology — Posted on 2019-04-18

1274 Deep learning with implicit handling of tissue-specific phenomena predicts tumor DNA accessibility and immune activity

Wnuk, K.; Sudol, J.; Givechian, K. B.; Soon-Shiong, P.; Rabizadeh, S.; Szeto, C.; Vaske, C.

10.1101/229385 — bioinformatics — Posted on 2019-04-18

1275 Characterising the vocal repertoire of the Indian wolf (Canis lupus pallipes)

Sadhukhan, S.; Hennelly, L.; Habib, B.

10.1101/612507 — animal behavior and cognition — Posted on 2019-04-18

1276 Comparing open-source toolboxes for processing and analysis of spike and local field potentials data

Unakafova, V. A.; Gail, A.

10.1101/600486 — neuroscience — Posted on 2019-04-18

1277 Integrated biphasic growth rate, gene expression, and cell-size homeostasis behaviour of single B. subtilis cells

Nordholt, N.; van Heerden, J. H.; Bruggeman, F. J.

10.1101/510925 — microbiology — Posted on 2019-04-18

1278 The Sibship Index can’t discriminates Half-Sibs from Full-Sibs; a new algorithm, including maternal genotype, can do it

Cardillo, G.

10.1101/265561 — bioinformatics — Posted on 2019-04-18

1279 Dual RNA-Seq meta-analysis in Plasmodium infection

Mukherjee, P.; Heitlinger, E.

10.1101/576116 — bioinformatics — Posted on 2019-04-18

1280 Alanine Metabolism in Bacillus subtilis

Sidiq, K. R.; Chow, M.; Zhao, Z.; Daniel, R.

10.1101/562850 — microbiology — Posted on 2019-04-18

1281 The molecular aetiology of tRNA synthetase depletion: induction of a GCN4 amino acid starvation response despite homeostatic maintenance of charged tRNA levels

McFarland, M. R.; Keller, C. D.; Childers, B. M.; Corrigall, H.; Raguin, A.; Romano, M. C.; Stansfield, I.

10.1101/610790 — systems biology — Posted on 2019-04-17

1282 Genome diversification, deleterious mutation accumulation, and evidence of negative selection among clonally propagated grapevines

Vondras, A.; Minio, A.; Blanco-Ulate, B.; Figueroa, R.; Penn, M.; Zhou, Y.; Seymour, D.; Zhou, Y.; Liang, D.; Espinoza, L.; Anderson, M.; Walker, M. A.; Gaut, B.; Cantu, D.

10.1101/585869 — genomics — Posted on 2019-04-17

1283 Identifying microbial species by single-molecule DNA optical mapping and resampling statistics

Bouwens, A.; Deen, J.; Vitale, R.; D'Huys, L.; Goyvaerts, V.; Descloux, A.; Borrenberghs, D.; Grussmayer, K.; Lukes, T.; Camacho, R.; Su, J.; Ruckebusch, C.; Lasser, T.; Van De Ville, D.; Hofkens, J.; Radenovic, A.; Janssen, K. P. F.

10.1101/609412 — genomics — Posted on 2019-04-17

1284 Mini-barcodes are equally useful for species identification and more suitable for large-scale species discovery in Metazoa than full-length barcodes

Yeo, D.; Srivathsan, A.; Meier, R.

10.1101/594952 — evolutionary biology — Posted on 2019-04-17

1285 Coupling metastasis to pH sensing G Protein-coupled receptor-68 through first in class inhibitor identified in an in vivo chemical genetic screen

Williams, C. H.; Thayer, T. E.; Keyesr, B. D.; Wani, M.; Wells, Q. S.; Hong, C. C.

10.1101/612549 — cancer biology — Posted on 2019-04-17

1286 Extension of the in vivo haploid induction system from diploid maize to hexaploid wheat

Liu, C.; Zhong, Y.; Qi, X.; Chen, M.; Liu, Z.; Chen, C.; Tian, X.; Li, J.; Jiao, Y.; Wang, D.; Wang, Y.; Li, M.; Xin, M.; Liu, W.; Jin, W.; Chen, S.

10.1101/609305 — plant biology — Posted on 2019-04-17

1287 Seascape genomics as a new tool to empower coral reef conservation strategies: an example on north-western Pacific Acropora digitifera.

Selmoni, O.; Rochat, E.; Lecellier, G.; Veronique, B.-L.; Joost, S.

10.1101/588228 — evolutionary biology — Posted on 2019-04-17

1288 Linking Demyelination to Compound Action Potential

Naud, R.; Longtin, A.

10.1101/501379 — neuroscience — Posted on 2019-04-17

1289 Robust 3D Bloch-Siegert based B1+ mapping using Multi-Echo General Linear Modelling

Corbin, N.; Acosta-Cabronero, J.; Malik, S. J.; Callaghan, M. F.

10.1101/550509 — neuroscience — Posted on 2019-04-17

1290 Maximal homology alignment: A new method based ontwo-dimensional homology

Erives, A. J.

10.1101/593228 — genetics — Posted on 2019-04-17

1291 The molecular clock of Mycobacterium tuberculosis

Menardo, F.; Duchene, S.; Brites, D.; Gagneux, S.

10.1101/532390 — evolutionary biology — Posted on 2019-04-17

1292 Genetic analysis of TP53 gene mutations in exon 4 and exon 8 among esophageal cancer patients in Sudan

Eltaher, S. M.; Idris, A. B.; H, M. A.; Mohamed Yousif, M. Y.; Mohamed, N. S.; Abdel Hamid, M. M.; Elsiddig, K. E.; Hassan, M. A.; Yousif, G. M.

10.1101/572214 — cancer biology — Posted on 2019-04-17

1293 Time Series Experimental Design Under One-Shot Sampling: The Importance of Condition Diversity

Kang, X.; Hajek, B.; Wu, F.; Hanzawa, Y.

10.1101/537548 — systems biology — Posted on 2019-04-17

1294 Directed networks as a novel way to describe and analyze cardiac excitation: Directed Graph mapping

Vandersickel, N.; Van Nieuwenhuyse, E.; Van Cleemput, N.; Goedgebeur, J.; El Haddad, M.; De Neve, J.; Demolder, A.; Strisciuglio, T.; Duytschaever, M.; Panfilov, A.

10.1101/596288 — physiology — Posted on 2019-04-17

1295 Human Foveal Cone Photoreceptor Topography and its Dependence on Eye Length

Wang, Y.; Bensaid, N.; Tiruveedhula, P.; Ma, J.; Ravikumar, S.; Roorda, A.

10.1101/589135 — neuroscience — Posted on 2019-04-17

1296 Neural Field Models for Latent State Inference: Application to Large-Scale Neuronal Recordings

Rule, M. E.; Schnoerr, D.; Hennig, M. H.; Sanguinetti, G.

10.1101/543769 — neuroscience — Posted on 2019-04-17

1297 Coarse-grain simulations on NMR conformational ensembles highlight non catalytic functional residues in proteins

Sacquin-Mora, S.

10.1101/532507 — molecular biology — Posted on 2019-04-17

1298 Combining amoxicillin and relebactam provides a new therapeutic option for Mycobacterium abscessus infection

Lopeman, R. C.; Harrison, J.; Gibson, S. E. R.; Rathbone, D. L.; Desai, M.; Lambert, P. A.; Cox, J. A. G.

10.1101/563189 — microbiology — Posted on 2019-04-17

1299 Gene regulatory network reconstruction using single-cell RNA sequencing of barcoded genotypes in diverse environments

Gresham, D.; Bonneau, R.; Jackson, C. A.; Castro, D. M.; Saldi, G.-A.

10.1101/581678 — genomics — Posted on 2019-04-17

1300 Predicting evolution using frequency-dependent selection in bacterial populations

Azarian, T.; Martinez, P. P. P.; Arnold, B. J.; Grant, L. R.; Corander, J.; Fraser, C.; Croucher, N.; Hammitt, L.; Reed, R.; Santosham, M.; Weatherholtz, R. R.; Bentley, S. D.; O'Brien, K. L.; Lipsitch, M.; Hanage, W. P.

10.1101/420315 — evolutionary biology — Posted on 2019-04-17

1301 The ER chaperone PfGRP170 is essential for asexual development and is linked to stress response in malaria parasites.

Kudyba, H. M.; Cobb, D. W.; Fierro, M. A.; Florentin, A.; Ljolje, D.; Singh, B.; Lucchi, N. W.; Muralidharan, V.

10.1101/406181 — cell biology — Posted on 2019-04-17

1302 Energy Landscape of the Domain Movement in Staphylococcus aureus UDP-N-acetylglucosamine 2-epimerase

de Azevedo, E. C.; Nascimento, A. S.

10.1101/535138 — biophysics — Posted on 2019-04-17

1303 Syntrophic co-culture amplification of production phenotype for high-throughput screening of microbial strain libraries

Saleski, T.; Kerner, A.; Chung, M. T.; Jackman, C.; Khasbaatar, A.; Kurabayashi, K.; Lin, X. N.

10.1101/518639 — synthetic biology — Posted on 2019-04-17

1304 A systematic genetic analysis and visualization of phenotypic heterogeneity among orofacial cleft GWAS signals

Carlson, J.; Anand, D.; Butali, A.; Buxo, C.; Christensen, K.; Deleyiannis, F.; Hecht, J.; Moreno-Uribe, L.; Orioli, I.; Padilla, C.; Shaffer, J.; Vieira, A.; Wehby, G.; Weinberg, S.; Murray, J.; Beaty, T.; Saadi, I.; Lachke, S.; Marazita, M.; Feingold, E.; Leslie, E.

10.1101/332270 — genetics — Posted on 2019-04-17

1305 Full-length de novo viral quasispecies assembly through variation graph construction

Baaijens, J.; van der Roest, B.; Koester, J.; Stougie, L.; Schoenhuth, A.

10.1101/287177 — bioinformatics — Posted on 2019-04-17

1306 Ablation of SUN2-containing LINC complexes drives cardiac hypertrophy without interstitial fibrosis

Stewart, R. M.; Rodriguez, E. C.; King, M. C.

10.1101/612150 — cell biology — Posted on 2019-04-17

1307 Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium

Goldfarbmuren, K. C.; Jackson, N. D.; Sajuthi, S. P.; Dyjack, N.; Li, K. S.; Rios, C. L.; Plender, E. G.; Montgomery, M. T.; Everman, J. L.; Vladar, E. K.; Seibold, M. A.

10.1101/612747 — cell biology — Posted on 2019-04-17

1308 A revised model for promoter competition based on multi-way chromatin interactions

Oudelaar, A. M.; Harrold, C. L.; Hanssen, L. L. P.; Telenius, J. M.; Higgs, D. R.; Hughes, J. R.

10.1101/612275 — genomics — Posted on 2019-04-17

1309 Integrating multiple genomic technologies to investigate an outbreak of carbapenemase-producing Enterobacter hormaechei

Roberts, L. W.; Harris, P. N. A.; Ben Zakour, N. L.; Forde, B. M.; Catchpoole, E.; Stanton-Cook, M.; Phan, M.-D.; Sidjabat, H.; Bergh, H.; Heney, C.; Gawthorne, J. A.; Lipman, J.; Allworth, A.; Chan, K.-G.; Chong, T. M.; Yin, W.-F.; Schembri, M. A.; Paterson, D. L.; Beatson, S.

10.1101/172536 — genomics — Posted on 2019-04-17

1310 Long noncoding RNAs sustain high expression of exogenous Oct4 by sponging miRNA during reprogramming

Kong, Q.; Zhang, X.; Zhang, J.; Zheng, K.; Zhang, H.; Pei, X.; Yin, Z.; Wen, D.; Liu, Z.

10.1101/612077 — cell biology — Posted on 2019-04-17

1311 A model for estimating traction force magnitude reveals differential regulation of actomyosin activity and matrix adhesion number in response to smooth muscle cell spreading

Warren, D.; Ahmed, S.; Mabeza, P.

10.1101/612267 — cell biology — Posted on 2019-04-17

1312 A transcallosal fiber system between homotopic inferior frontal regions supports complex linguistic processing

Kellmeyer, P.; Vry, M.-S.; Ball, T.

10.1101/079244 — neuroscience — Posted on 2019-04-17

1313 Atg8a interacts with transcription factor Sequoia to control the expression of autophagy genes in Drosophila

Jacomin, A.-C.; Petridi, S.; DiMonaco, M.; Jain, A.; Bhujabal, Z.; Mulakkal, N.; Palara, A.; Powell, E.; Chung, B.; Zampronio, C.; Jones, A.; Cameron, A.; Johansen, T.; Nezis, I.

10.1101/611731 — cell biology — Posted on 2019-04-17

1314 The coordinate actions of calcineurin and Hog1 mediate the response to cellular stress through multiple nodes of the cell cycle network

Leech, C. M.; Flynn, M. J.; Arsenault, H. E.; Ou, J.; Liu, H.; Zhu, L. J.; Benanti, J.

10.1101/612416 — cell biology — Posted on 2019-04-17

1315 Centromere clustering stabilizes meiotic homolog pairing

Sekelsky, J.; Hatkevich, T. L.; Boudreau, V.; Rubin, T.; Maddox, P. S.; Huynh, J.-R.

10.1101/612051 — cell biology — Posted on 2019-04-17

1316 The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation

Batki, J.; Schnabl, J.; Wang, J.; Handler, D.; Andreev, V.; Stieger, C.; Novatchkova, M.; Lampersberger, L.; Kauneckaite, K.; Mechtler, K.; Patel, D.; Brennecke, J.

10.1101/609693 — molecular biology — Posted on 2019-04-17

1317 Development of behavioral modernity by hominins around 70,000 years ago was associated with simultaneous acquisition of a novel component of imagination, called prefrontal synthesis, and conversion of a preexisting rich-vocabulary non-recursive communication system to a fully recursive syntactic language

Vyshedskiy, A.

10.1101/166520 — evolutionary biology — Posted on 2019-04-17

1318 Osteocytes remodel bone by TGF-β-induced YAP/TAZ signaling

Kegelman, C. D.; Coulombe, J. C.; Jordan, K. M.; Horan, D. J.; Qin, L. D.; Robling, A. G.; Ferguson, V. L.; Bellido, T. M.; Boerckel, J. D.

10.1101/611913 — cell biology — Posted on 2019-04-17

1319 ANKLE2, a target of Zika virus, controls asymmetric cell division of neuroblasts and uncovers a novel microcephaly pathway

Link, N.; Chung, H.; Jolly, A.; Withers, M.; Tepe, B.; Arenkiel, B. R.; Shah, P. S.; Krogan, N. J.; Aydin, H.; Geckinli, B. B.; Tos, T.; Isikay, S.; Tuysuz, B.; Mochida, G. H.; Thomas, A. X.; Clark, R. D.; Mirzaa, G. M.; Lupski, J. R.; Bellen, H. J.

10.1101/611384 — genetics — Posted on 2019-04-17

1320 Regardless of the deposition pathway, aminoacid 31 in histone variant H3 is essential at gastrulation in Xenopus

Sitbon, D.; Boyarchuk, E.; Almouzni, G.

10.1101/612515 — developmental biology — Posted on 2019-04-17

1321 Deep learning for cancer type classification

Zeng, Z.; Mao, C.; Vo, A.; Nugent, J. O.; Khan, S. A.; Clare, S. E.; Luo, Y.

10.1101/612762 — cancer biology — Posted on 2019-04-17

1322 Coupling metastasis to pH sensing G Protein-coupled receptor-68 through first in class inhibitor identified in an in vivo chemical genetic screen

Williams, C. H.; Thayer, T.; Keyesr, B.; Wani, M.; Wells, Q.; Hong, C. C.

10.1101/612549 — cancer biology — Posted on 2019-04-17

1323 Living cell-only bioink and photocurable supporting medium for printing and generation of engineered tissues with complex geometries

Jeon, O.; Lee, Y. B.; Jeong, H.; Lee, S. J.; Alsberg, E.

10.1101/611525 — bioengineering — Posted on 2019-04-17

1324 Gibbs Process Determines Survival and Reveals Contact-Inhibition Genes in Glioblastoma Multiforme

Kannan, L.; Agarwal, T.; Snuderl, M.; Zagzag, D.; Sulman, E.; Huse, J.; Kannan, K.

10.1101/608414 — cancer biology — Posted on 2019-04-17

1325 deSALT: fast and accurate long transcriptomic read alignment with de Bruijn graph-based index

Liu, B.; Liu, Y.; Zang, T.; Wang, Y.

10.1101/612176 — bioinformatics — Posted on 2019-04-17

1326 Differential gene expression analysis reveals novel genes and pathways in pediatric septic shock patients

Mohammed, A.; Cui, Y.; Mas, V. R.; Kamaleswaran, R.

10.1101/611947 — bioinformatics — Posted on 2019-04-17

1327 The conserved metalloprotease invadolysin is present in invertebrate haemolymph and vertebrate blood

Heck, M.; Abhinav, K.; Feng, L.; Morrison, E.; Jung, Y.; Dear, J.; Takahashi, S.

10.1101/612127 — cell biology — Posted on 2019-04-17

1328 Macrophages employ quorum licensing to regulate collective activation

Muldoon, J. J.; Chuang, Y.; Bagheri, N.; Leonard, J. N.

10.1101/610592 — systems biology — Posted on 2019-04-17

1329 Neurobehavioural signatures of learning that emerge in a real-world motor skill task

Haar, S.; van Assel, C. M.; Faisal, A. A.

10.1101/612218 — neuroscience — Posted on 2019-04-17

1330 Cell type-specific genetic regulation of expression in the granule cell layer of the human dentate gyrus

Jaffe, A. E.; Hoeppner, D. J.; Saito, T.; Blanpain, L.; Ukaigwe, J.; Burke, E. E.; Tao, R.; Tajinda, K.; Deep-Soboslay, A.; Shin, J. H.; Kleinman, J. E.; Weinberger, D. R.; Matsumoto, M.; Hyde, T. M.

10.1101/612200 — neuroscience — Posted on 2019-04-17

1331 Resveratrol prevents amyloid fibrillation of insulin by arresting it in a bioactive oligomeric form

Pathak, B. k.; Das, D.; Bhakta, S.; Chakrabarti, P.; Sengupta, J.

10.1101/611376 — biochemistry — Posted on 2019-04-17

1332 Transcriptional analysis identifies novel biomarkers associated with successful ex-vivo perfusion of human donor lungs

Ferdinand, J. R.; Morrison, M. I.; Andreasson, A.; Charlton, C.; Chhatwal, A.; Scott, W. E.; Borthwick, L. A.; Clatworthy, M. R.; Fisher, A. J.

10.1101/612374 — physiology — Posted on 2019-04-17

1333 The feasibility of atrial and ventricular arrhythmias recognition using metrics of signal complexity for heartbeat intervals

Huang, M.; Kido, K.; Ono, N.; Altaf-UI-Amin, M.; Tamura, T.; Kanaya, S.

10.1101/612002 — physiology — Posted on 2019-04-17

1334 Spatio-Temporal Dynamics of Landscape Use by the Bumblebee Bombus atratus (Hymenoptera: Apidae) and its relationship with pollen provisioning.

Cavigliasso, P.; Phifer, C.; Adams, E.; Flaspohler, D.; Gennari, G.; Licata, J.; Chacoff, N.

10.1101/612564 — ecology — Posted on 2019-04-17

1335 The link between supplementary tannin level and conjugated linoleic acid (CLA) formation in ruminants: A meta-analysis

Purba, R. A. P.; Paengkoum, P.; Paengkoum, S.

10.1101/612523 — physiology — Posted on 2019-04-17

1336 The first Miocene fossils of Lacerta cf. trilineata (Squamata, Lacertidae) with a comparative study of the main cranial osteological differences in green lizards and their relatives

Cernansky, A.; Syromyatnikova, E. V.

10.1101/612572 — paleontology — Posted on 2019-04-17

1337 Defining Escherichia coli as a health-promoting microbe against intestinal Pseudomonas aeruginosa

Christofi, T.; Panayidou, S.; Dieronitou, i.; Michael, C.; Apidianakis, Y.

10.1101/612606 — microbiology — Posted on 2019-04-17

1338 The right microbial stimulus can direct innate immune effector cells to specific organ sites to clear pathology

Kalyan, S.; Bazett, M.; Sham, H. P.; Bosiljcic, M.; Luk, B.; Dhanji, S.; Costa, A.; Wong, S.; Netea, M.; Mullins, D.; Gunn, H.

10.1101/612598 — immunology — Posted on 2019-04-17

1339 Implicit learning and exploitation of regularities involve hippocampal and prefrontal theta activity

Spaak, E.; de Lange, F. P.

10.1101/611129 — neuroscience — Posted on 2019-04-17

1340 Quantifying the individual auditory and visual brain response in 7- month-old infants watching a brief cartoon movie

Jessen, S.; Fiedler, L.; Muente, T.; Obleser, J.

10.1101/610709 — neuroscience — Posted on 2019-04-17

1341 Muropeptides Stimulate Growth Resumption from Stationary Phase in Escherichia coli

Joers, A.; Vind, K.; Hernandez, S. B.; Maruste, R.; Pereira, M. D.; Brauer, A.; Remm, M.; Cava, F.; Tenson, T.

10.1101/611111 — microbiology — Posted on 2019-04-17

1342 piRNA-mediated silencing of an invading transposable element evolves rapidly through abundant beneficial de novo mutations

Zhang, S.; Kelleher, E.

10.1101/611350 — evolutionary biology — Posted on 2019-04-17

1343 The transmission of Hand, Foot, and Mouth Disease in East and Southeast Asia

zhao, j.; Wang, Y.

10.1101/612580 — epidemiology — Posted on 2019-04-17

1344 Gene regulatory network inference and analysis of multidrug-resistant Pseudomonas aeruginosa

Medeiros Filho, F.; Nascimento, A. P. B.; Trindade dos Santos, M.; Carvalho-Assef, A. P. D.; Silva, F. A. B.

10.1101/610493 — systems biology — Posted on 2019-04-17

1345 Physiotherapists perceptions on informed consent and role in the healthcare system, in Europe

Roman, N.; Caloian, S.; Repanovici, A.; Miclaus, R. S.; Sechel, G.; Rogozea, L.

10.1101/612473 — scientific communication and education — Posted on 2019-04-17

1346 Application of Different Types of Lactic Acid Bacteria Inoculant on Ensiled Rice Straw; Effects on Silage Quality, Rumen Fermentation, Methane Production and Microbial Population

Ebrahimi, M.; Oskoueian, E.; Jafari, S.; Noura, R.; Jahromi, M. F.; Meng, G. Y.

10.1101/612556 — physiology — Posted on 2019-04-17

1347 Homozygous NMNAT2 mutation in sisters with polyneuropathy and erythromelalgia

Huppke, P.; Wegener, E.; Gilley, J.; Angeletti, C.; Kurth, I.; Drenth, J. P. H.; Stadelmann, C.; Barrantes-Freer, A.; Brück, W.; Thiele, H.; Nürnberg, P.; Gärtner, J.; Orsomando, G.; Coleman, M.

10.1101/610907 — neuroscience — Posted on 2019-04-17

1348 Identifying site- and stimulation-specific TMS-evoked EEG potentials using a quantitative cosine similarity metric

Freedberg, M. V.; Reeves, J. A.; Hussain, S. J.; Zaghloul, K. A.; Wassermann, E. M.

10.1101/612499 — neuroscience — Posted on 2019-04-17

1349 Improvements in upper extremity function in children with unilateral spastic cerebral palsy after intensive training correlates with interhemispheric connectivity

Robert, M. T.; Gutterman, J.; Ferre, C. L.; Chin, K.; Brandao, M. B.; Gordon, A. M.; Friel, K. M.

10.1101/609313 — neuroscience — Posted on 2019-04-17

1350 Eimeria falciformis BayerHaberkorn1970 and novel wild derived isolates from house mice: differences in parasite lifecycle, pathogenicity and host immune reactions

Al Klifeh, E.; Balard, A.; Jarquin-Diaz, V. H.; Weyrich, A.; Wibbelt, G.; Heitlinger, E.

10.1101/611277 — microbiology — Posted on 2019-04-17

1351 Ecological and evolutionary patterns in the enigmatic protist genus Percolomonas (Heterolobosea; Discoba) from diverse habitats

Tikhonenkov, D. V.; Jhin, S. H.; Eglit, Y.; Miller, K.; Plotnikov, A.; Simpson, A. G. B.; Park, J. S.

10.1101/612531 — microbiology — Posted on 2019-04-17

1352 Ifit1 regulates norovirus infection and enhances the interferon response in murine macrophage-like cells.

Mears, H. V.; Emmott, E.; Chaudhry, Y.; Hosmillo, M.; Goodfellow, I. G.; Sweeney, T. R.

10.1101/611236 — immunology — Posted on 2019-04-17

1353 Behavioural and metabolic consequences after a single generation of angling selection in brown trout

Prokkola, J. M.; Alioravainen, N.; Mehtatalo, L.; Hyvarinen, P.; Lemopoulos, A.; Metso, S.; Vainikka, A.

10.1101/611293 — animal behavior and cognition — Posted on 2019-04-17

1354 Hello, is that me you are looking for? A re-examination of the role of the DMN in off-task thought

Murphy, C.; Poerio, G.; Sormaz, M.; Wang, H.-T.; Vatansever, D.; Allen, M.; Margulies, D. S.; Jefferies, E.; Smallwood, J.

10.1101/612465 — neuroscience — Posted on 2019-04-17

1355 Induction of Chk2 signaling in the germarium is sufficient to cause oogenesis arrest in Drosophila

Ephrussi, A.; Durdevic, Z.

10.1101/611798 — developmental biology — Posted on 2019-04-17

1356 Impact of within-tree organ distances on floral induction and fruit growth in apple tree: implication of carbon and gibberellin organ contents

Belhassine, F.; Martinez, S.; Bluy, S.; Fumey, D.; Kelner, J.-J.; Costes, E.; Pallas, B.

10.1101/612317 — plant biology — Posted on 2019-04-17

1357 Intraspecific root and leaf trait variation with tropical forest successional status: consequences for community-weighted patterns

Hogan, A.; Valverde-Barrantes, O. J.; Ding, Q.; Xu, H.; Baraloto, C.

10.1101/611640 — plant biology — Posted on 2019-04-17

1358 Extension of the in vivo haploid induction system from diploid maize to hexaploid wheat

Liu, C.; Zhong, Y.; Qi, X.; Chen, M.; Liu, Z.; Chen, C.; Tian, X.; Li, J.; Jiao, Y.; Wang, D.; Wang, Y.; Li, M.; Xin, M.; Liu, W.; Jin, W.; Chen, S.

10.1101/609305 — plant biology — Posted on 2019-04-17

1359 Chitin perception in plasmodesmata identifies subcellular, context-specific immune signalling in plants

Cheval, C.; Johnston, M.; Samwald, S.; Liu, X.; Bellandi, A.; Breakspear, A.; Kadota, Y.; Zipfel, C.; Faulkner, C.

10.1101/611582 — plant biology — Posted on 2019-04-17

1360 Whole-genome reference panel of 1,781 Northeast Asians improves imputation accuracy of rare and low-frequency variants

Yoo, S.-K.; Kim, C.-U.; Kim, H. L.; Kim, S.; Shin, J.-Y.; Kim, N.; Yang, J. S.; Lo, K.-W.; Cho, B.; Matsuda, F.; Schuster, S. C.; Kim, C.; Kim, J.-I.; Seo, J.-S.

10.1101/600353 — genomics — Posted on 2019-04-17

1361 Music-listening regulates human microRNA transcriptome

Nair, P. S.; Raijas, P.; Ahvenainen, M.; Philips, A. K.; Ukkola-Vuoti, L.; Jarvela, I.

10.1101/599217 — genomics — Posted on 2019-04-17

1362 Sparse Project VCF: efficient encoding of population genotype matrices

Lin, M. F.; Bai, X.; Salerno, W. J.; Reid, J. G.

10.1101/611954 — bioinformatics — Posted on 2019-04-17

1363 Auxin-mediated rapid degradation of selective proteins in hippocampal neurons

Nakano, R.; Ihara, N.; Morikawa, S.; Nakashima, A.; Kanemaki, M.; Ikegaya, Y.; Takeuchi, H.

10.1101/612119 — neuroscience — Posted on 2019-04-17

1364 Comparative analysis of perennial and annual Phaseolus seed nutrient concentrations

Schier, H. E.; Eliot, K. A.; Herron, S. A.; Landfried, L. K.; Migicovsky, Z.; Rubin, M. J.; Miller, A. J.

10.1101/612010 — plant biology — Posted on 2019-04-17

1365 Euclidean distance as a measure to distinguish ventral and dorsal white matter connectivity in the human brain

Kellmeyer, P.; Vry, M.-S.

10.1101/053959 — neuroscience — Posted on 2019-04-17

1366 Full-coverage sequencing of HIV-1 provirus from a reference plasmid

Gener, A. R.

10.1101/611848 — genomics — Posted on 2019-04-17

1367 Temporal variation of fatty acid composition and pesticides in honeybees Apis mellifera and beebread

Gooley, Z. C.; Gooley, A.

10.1101/572149 — zoology — Posted on 2019-04-17

Covarrubias, A. J.; Lopez-Dominguez, J. A.; Perrone, R.; Kale, A.; Newman, J.; Iyer, S. S.; Schmidt, M. S.; Kasler, H. G.; Shin, K.-O.; Lee, Y.-M.; Ben-Sahra, I.; Ott, M.; Brenner, C.; Campisi, J.; Verdin, E.

10.1101/609438 — immunology — Posted on 2019-04-17

1369 Molecular Diversity and Network Complexity in Growing Protocells

Kamimura, A.; Kaneko, K.

10.1101/611996 — biophysics — Posted on 2019-04-17

1370 BioSAXS measurements reveal that two antimicrobial peptides induce similar molecular changes in Gram-negative and Gram-positive bacteria

von Gundlach, A.; Ashby, M.; Gani, J.; Lopez-Perez, P. M.; Cookson, A.; Huws, S.; Rumancev, C.; Garamus, V. M.; Mikut, R.; Rosenhahn, A.; Hilpert, K.

10.1101/611608 — biophysics — Posted on 2019-04-17

1371 Conformational Priming of RepA-WH1 for Functional Amyloid Conversion Detected by NMR Spectroscopy

Pantoja-Uceda, D.; Oroz, J.; Fernandez, C.; de Alba, E.; Giraldo, R.; Laurents, D.

10.1101/612135 — biochemistry — Posted on 2019-04-17

1372 Detection and characterization of a novel copper-dependent intermediate in a lytic polysaccharide monooxygenase

Singh, R. K.; Oort, B. v.; Mollers, B.; Russo, D. A.; Singh, R.; Weihe, H.; Tiwari, M. K.; Croce, R.; Jensen, P. E.; Felby, C.; Bjerrum, M. J.

10.1101/610865 — biochemistry — Posted on 2019-04-17

1373 Importance of erythrocyte deformability for the alignment of malaria parasite upon invasion

Hillringhaus, S.; Gompper, G.; Fedosov, D. A.

10.1101/611269 — biophysics — Posted on 2019-04-17

1374 Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes

Temoche-Diaz, M. M.; Shurtleff, M. J.; Nottingham, R. M.; Yao, J.; Fadadu, R. P.; Lambowitz, A. M.; Schekman, R.

10.1101/612069 — biochemistry — Posted on 2019-04-17

1375 Novel lead compounds that target the ribosomal peptidyl transferase center

Tam, B.; Sherf, D.; Cohen, S.; Eisdorfer, S. A.; Perez, M.; Soffer, A.; Vilenchik, D.; Wagner, G.; Akabayov, B.

10.1101/604777 — biochemistry — Posted on 2019-04-17

1376 The more the merrier? Multivariate approaches to genome-wide association analysis

Vroom, C.-R.; de Leeuw, C.; Posthuma, D.; Dolan, C. V.; van der Sluis, S.

10.1101/610287 — genetics — Posted on 2019-04-17

1377 Machine learning prediction of emesis and gastrointestinal state in ferrets

Nanivadekar, A. C.; Miller, D. M.; Fulton, S.; Wong, L.; Ogren, J.; Chitnis, G.; McLaughlin, B.; Zhai, S.; Fisher, L. E.; Yates, B. J.; Horn, C. C.

10.1101/607242 — neuroscience — Posted on 2019-04-17

1378 A highly responsive pyruvate sensor reveals pathway-regulatory role of the mitochondrial pyruvate carrier MPC

Arce-Molina, R.; Cortes-Molina, F.; Sandoval, P. Y.; Galaz, A.; Alegria, K.; Schirmeier, S.; Barros, L. F.; San Martin, A.

10.1101/611806 — cell biology — Posted on 2019-04-17

1379 Human co-transcriptional splicing kinetics and coordination revealed by direct nascent RNA sequencing

Drexler, H. L.; Choquet, K.; Churchman, L. S.

10.1101/611020 — molecular biology — Posted on 2019-04-17

1380 Endophytic Virome

Das, S.; Barooah, M.; Thakur, N.

10.1101/602144 — microbiology — Posted on 2019-04-17

1381 A new immunotherapeutic concept for pancreatic cancer using childhood vaccine recall antigens and Listeria

Selvanesan, B. C.; Chandra, D.; Quispe-Tintaya, W.; Jahangir, A.; Patel, A.; Meena, K.; Alberto Alves Da Silva, R.; Libutti, S. K.; Yuan, Z.; Beck, A.; Tesfa, L.; Koba, W.; Chuy, J.; McAuliffe, J. C.; Jafari, R.; Entenberg, D.; Wang, Y.; Condeelis, J.; Gravekamp, C.

10.1101/600106 — immunology — Posted on 2019-04-17

1382 Reward motivation modulates representation of behaviorally-relevant information across the frontoparietal cortex

Shashidhara, S.; Erez, Y.

10.1101/609537 — neuroscience — Posted on 2019-04-17

1383 The effects of soil phosphorous content on microbiota are driven by the plant phosphate starvation response

Finkel, O. M.; Salas-Gonzalez, I.; Castrillo, G.; Spaepen, S.; Law, T. F.; Jones, C.; Dangl, J. L.

10.1101/608133 — microbiology — Posted on 2019-04-17

1384 Modelling the On-going Natural Selection of Educational Attainment in Contemporary Societies

Hong, Z.

10.1101/605311 — evolutionary biology — Posted on 2019-04-17

1385 Icosahedral viruses defined by their positively charged domains: a signature for viral identity and capsid assembly strategy

Requiao, R. D.; Carneiro, R. L.; Moreira, M. H.; Ribeiro-Alves, M.; Rossetto, S.; Palhano, F.; Domitrovic, T.

10.1101/600981 — bioinformatics — Posted on 2019-04-17

1386 PyRates - A Python Framework for Rate-Based Neural Simulations

Gast, R.; Rose, D. F.; Moeller, H. E.; Weiskopf, N.; Knoesche, T. R.

10.1101/608067 — neuroscience — Posted on 2019-04-17

1387 Efflux pumps in Chromobacterium species and their involvement in antibiotic tolerance and survival in a co-culture competition model

Benomar, S.; Evans, K. C.; Unckless, R.; Chandler, J. R.

10.1101/562140 — microbiology — Posted on 2019-04-16

1388 Impact of NaCl, nitrate and temperature on the microbial community of a methanol-fed, denitrifying marine biofilm

Villemur, R.; Payette, G.; Geoffroy, V.; Mauffrey, F.; Martineau, C.

10.1101/607028 — microbiology — Posted on 2019-04-16

1389 Evaluating the within-host dynamics of Ranavirus infection with mechanistic disease models and experimental data

Mihaljevic, J. R.; Greer, A. L.; Brunner, J. L.

10.1101/564120 — ecology — Posted on 2019-04-16

1390 Constitutive IRE1α signaling maintains glioblastoma cell differentiation

10.1101/594630 — cancer biology — Posted on 2019-04-16

1391 The Inter and Intra-Tumoural Heterogeneity of Subclonal Reconstruction

Bhandari, V.; Liu, L. Y.; Salcedo, A.; Espiritu, S. M.; Morris, Q. D.; Boutros, P. C.

10.1101/418780 — cancer biology — Posted on 2019-04-16

1392 Gibbs Process Determines Survival and Reveals Contact-Inhibition Genes in Glioblastoma Multiforme

Kannan, L.; Agarwal, T.; Fenyo, D.; Tsirigos, A.; Snuderl, M.; Zagzag, D.; Sulman, E.; Huse, J.; Kannan, K.

10.1101/608414 — cancer biology — Posted on 2019-04-16

1393 Interaction of Hippocampal Ripples and Cortical Slow Waves Leads to Coordinated Large-Scale Sleep Rhythm

Sanda, P.; Malerba, P.; Jiang, X.; Krishnan, G.; Cash, S.; Halgren, E.; Bazhenov, M.

10.1101/568881 — neuroscience — Posted on 2019-04-16

1394 An Alternative Framework for Fluorescence Correlation Spectroscopy

Jazani, S.; Sgouralis, I.; Shafraz, O. M.; Levitus, M.; Sivasankar, S.; Presse, S.

10.1101/426114 — biophysics — Posted on 2019-04-16

1395 A Bayesian framework for unifying data cleaning, source separation and imaging of electroencephalographic signals

Ojeda, A.; Klug, M.; Kreutz-Delgado, K.; Gramann, K.; Mishra, J.

10.1101/559450 — neuroscience — Posted on 2019-04-16

1396 netNMF-sc: Leveraging gene-gene interactions for imputation and dimensionality reduction in single-cell expression analysis

Elyanow, R.; Dumitrascu, B.; Engelhardt, B. E.; Raphael, B. J.

10.1101/544346 — genomics — Posted on 2019-04-16

1397 Intrinsic structure of model-derived metrics for in silico proarrhytmic risk assessment identified by global sensitivity analysis

Parikh, J.; Di Achille, P.; Kozloski, J.; Gurev, V.

10.1101/543926 — pharmacology and toxicology — Posted on 2019-04-16

1398 Deep Brain Stimulation of the Prelimbic Cortex Disrupts Consolidation of Fear Memories

Tan, S. Z. K.; Poon, C. H.; Chan, Y.-S.; Lim, L. W.

10.1101/537514 — neuroscience — Posted on 2019-04-16

1399 RNA-DNA hybrids support recombination-based telomere maintenance in fission yeast

Hu, Y.; Bennett, H. W.; Liu, N.; Moravec, M.; Williams, J. F.; Azzalin, C. M.; King, M. C.

10.1101/458968 — genetics — Posted on 2019-04-16

1400 The comparative biogeography of Philippine geckos challenges predictions from a paradigm of climate-driven vicariant diversification across an island archipelago

Oaks, J. R.; Siler, C. D.; Brown, R. M.

10.1101/395434 — evolutionary biology — Posted on 2019-04-16

1401 Modelling depolarization delay, sodium currents, and electrical potentials in cardiac transverse tubules

Vermij, S. H.; Abriel, H.; Kucera, J. P.

10.1101/611558 — physiology — Posted on 2019-04-16

1402 piRNA-guided co-transcriptional silencing coopts nuclear export factors

Fabry, M. H.; Ciabrelli, F.; Munafo, M.; Eastwood, E. L.; Kneuss, E.; Falciatori, I.; Falconio, F. A.; Hannon, G. J.; Czech, B.

10.1101/611343 — molecular biology — Posted on 2019-04-16

1403 Expansion of a fly TBI model to four levels of injury severity reveals synergistic effects of repetitive injury for moderate injury conditions

Putnam, L. J.; Willes, A. M.; Kalata, B. E.; Disher, N. D.; Brusich, D. J.

10.1101/611244 — neuroscience — Posted on 2019-04-16

1404 PP1 and PP2A use opposite phospho-dependencies to control distinct processes at the kinetochore

Smith, R. J.; Cordeiro, M. H.; Davey, N. E.; Vallardi, G.; Ciliberto, A.; Gross, F.; Saurin, A. T.

10.1101/610808 — cell biology — Posted on 2019-04-16

1405 Nuclear deformation and anchorage defect induced by DCM mutants in lamin A

Bera, M.; Kumar, R.; Sinha, B.; Sengupta, K.

10.1101/611665 — cell biology — Posted on 2019-04-16

1406 CD117/c-kit Represents a Prostate Cancer Stem-Like Subpopulation Driving Progression, Migration, and TKI Resistance

Harris, K.; Shi, L.; Foster, B.; Mobley, M.; Elliott, P.; Song, C.; Langefeld, C.; Kerr, B.

10.1101/256107 — cancer biology — Posted on 2019-04-16

1407 Characterization of Amino Acid Recognition in Aminoacyl-tRNA Synthetases

Kaiser, F.; Krautwurst, S.; Salentin, S.; Haupt, V. J.; Leberecht, C.; Bittrich, S.; Labudde, D.; Schroeder, M.

10.1101/606459 — bioinformatics — Posted on 2019-04-16

1408 Uncovering the Binding Mode of γ-Secretase Inhibitors

Hitzenberger, M.; Zacharias, M.

10.1101/611194 — biophysics — Posted on 2019-04-16

1409 Multidimensional analysis of extended molecular dynamics simulations shows the complexity of signal transduction by the histamine H3 membrane receptor

Herrera-Zuniga, L. D.; Moreno-Vargas, L. M.; Correa-Basurto, J.; Prada, D.; Curmi, P.; Arrang, J.-M.; Maroun, R. C.

10.1101/604793 — bioinformatics — Posted on 2019-04-16

1410 Gibbs Process Determines Survival and Reveals Contact-Inhibition Genes in Glioblastoma Multiforme

Kannan, L.; Agarwal, T.; Fenyo, D.; Tsirigos, A.; Snuderl, M.; Zagzag, D.; Sulman, E.; Huse, J.; Kannan, K.

10.1101/608414 — cancer biology — Posted on 2019-04-16

1411 Identifying and validating housekeeping hybrid Prunus sp. genes for root gene-expression studies

Bastias, A.; Oviedo, K.; Almada, R.; Correa, F.; Sagredo, B.

10.1101/611004 — plant biology — Posted on 2019-04-16

1412 Incidence, predictors and reasons for initial regimen modifications in patients on antiretroviral therapy in Witbank, South Africa, 2003-2017

Bapela, M. P.; Kuonza, L. R.; Musekiwa, A.; Summers, R.

10.1101/610956 — epidemiology — Posted on 2019-04-16

1413 Nutritional Status and its Related Factors in Khalwa Residents, Khartoum state, Sudan.

Giha, I. H.; Shaddad, M. I.; Yusuf, A.; Paga, I. A.; Noma, M.; Homeida, M.

10.1101/610972 — epidemiology — Posted on 2019-04-16

1414 Improvement of bone regeneration using fibrin biopolymer combined with differentiated stem cells

Zorzella Creste, C. F.; Orsi, P. R.; Landim-Alvarenga, F. C.; Justulin, L. A.; Golim, M. d. A.; Barraviera, B.; Ferreira, R. S.

10.1101/608166 — bioengineering — Posted on 2019-04-16

1415 Sex differences in post-stroke aphasia rates are caused by age. A meta-analysis and database query

Wallentin, M.

10.1101/407296 — neuroscience — Posted on 2019-04-16

1416 Prevalence of Schistosoma mansoni infection in Ethiopia: A systematic review and meta-analysis

adem, s. h.; Assegu, D.; Shimelis, T.

10.1101/610113 — microbiology — Posted on 2019-04-16

1417 Bottom trawl catch comparison in the Mediterranean Sea: Flexible Turtle Excluder Device (TED) vs traditional gear

Vasapollo, C.; Virgili, M.; Petetta, A.; Bargione, G.; Sala, A.; Lucchetti, A.

10.1101/610089 — ecology — Posted on 2019-04-16

1418 The caudate nucleus controls coordinated patterns of adaptive, context-dependent adjustments to complex decisions

Doi, T.; Fan, Y.; Gold, J. I.; Ding, L.

10.1101/568733 — neuroscience — Posted on 2019-04-16

1419 Serum triglycerides in Alzheimer’s disease: Relation to neuroimaging and CSF biomarkers

Bernath, M.; Bhattacharyya, S.; Nho, K.; Barupal, D.; Fiehn, O.; Baillie, R.; Risacher, S.; Arnold, M.; Jacobson, T.; Trojanowski, J. Q.; Shaw, L. M.; Weiner, M. W.; Doraiswamy, P. M.; Kaddurah-Daouk, R.; Saykin, A. J.

10.1101/441394 — neuroscience — Posted on 2019-04-16

1420 Body mass index, earnings and partnership: genetic instrumental variable analysis in two nationally representative UK samples

Hughes, A. M.; Bao, Y.; Smart, M.; Kumari, M.

10.1101/608588 — epidemiology — Posted on 2019-04-16

1421 The pace of life: Time, temperature, and a biological theory of relativity

Neuheimer, A. B.

10.1101/609446 — ecology — Posted on 2019-04-16

1422 High accuracy DNA sequencing on a small, scalable platform via electrical detection of single base incorporations

Esfandyarpour, H.; Parizi, K. B.; Rezaei Barmi, M.; Rategh, H.; Wang, L.; Paliwal, S.; Golnabi, H. R.; Kenney, P.; Reel, R.; Lee, F.; Gomes, X.; Stern, S.; Ramachandran, A.; Sankar, S.; Doomson, S.; Ung, R.; Jouzi, M.; Akula Suresh Babu, R.; Nabi, A.; Castillo, N.; Lei, R.; Fallahi, M.; LoPrete, E.; Kemper, A.; Bagchi, S.; Tarbox, R.; Choudhary, P.; Nezamfar, H.; Hsie, L.; Monier, N.; Clark, T. A.; Spence, E.; Yang, F.; Bronson, B.; Sutton, G.; Schweidenback, C.; Lundy, J.; Ho, A.; Tangprasertchai, N.; Thomas, A.; Baxter, B.; Shastry, S.; Barua, A.; Chen, Y.; Hashemzadeh, H.; Shtern, D.; Kim,

10.1101/604553 — genomics — Posted on 2019-04-16

1423 Benchmarking of alignment-free sequence comparison methods

Zielezinski, A.; Girgis, H. Z.; Bernard, G.; Leimeister, C.-A.; Tang, K.; Dencker, T.; Lau, A. K.; Roehling, S.; Choi, J.; Waterman, M. S.; Comin, M.; Kim, S.-H.; Vinga, S.; Almeida, J. S.; Chan, C. X.; James, B.; Sun, F.; Morgenstern, B.; Karlowski, W. M.

10.1101/611137 — bioinformatics — Posted on 2019-04-16

1424 Magia: Robust automated modeling and image processing toolbox for PET neuroinformatics

Karjalainen, T.; Santavirta, S.; Kantonen, T.; Tuisku, J.; Tuominen, L.; Hirvonen, J.; Hietala, J.; Rinne, J.; Nummenmaa, L.

10.1101/604835 — neuroscience — Posted on 2019-04-16

1425 SPINT1 regulates the aggressiveness of skin cutaneous melanoma and its crosstalk with tumor immune microenvironment

Gomez-Abenza, E.; Ibanez-Molero, S.; Garcia-Moreno, D.; Fuentes-Martinez, I.; Zon, L.; Mione, M. C.; Cayuela, M. L.; Gabellini, C.; Mulero, V.

10.1101/611145 — cancer biology — Posted on 2019-04-16

1426 Protein engineering expands the effector recognition profile of a rice NLR immune receptor

De la Concepcion, J. C.; Franceschetti, M.; Terauchi, R.; Kamoun, S.; Banfield, M. J.

10.1101/611152 — plant biology — Posted on 2019-04-16

1427 Human co-transcriptional splicing kinetics and coordination revealed by direct nascent RNA sequencing

Drexler, H. L.; Choquet, K.; Churchman, L. S.

10.1101/611020 — molecular biology — Posted on 2019-04-16

1428 Phylo-comparative analyses reveal the dual role of drift and selection in reproductive character displacement.

Saglam, I. K.; Miller, M.; O'Rourke, S.; Caglar, S. S.

10.1101/610857 — evolutionary biology — Posted on 2019-04-16

1429 Protein-protein interaction network topology as a measure of bacterial plasmid-chromosome co-evolution

Tran, N. T. H.; Decano, A. G.; Downing, T.; Rahm, A. D.

10.1101/610774 — bioinformatics — Posted on 2019-04-16

1430 Cloning, Biochemical Characterization and inhibition of Alanine racemase from Streptococcus iniae

Muhammad, M.; Li, Y.; Gong, S.; Shi, Y.; Ju, J.; Baohua, Z.; Liu, D.

10.1101/611251 — biochemistry — Posted on 2019-04-16

1431 Parallel Streams to Interconnected Networks: Organization and Reorganization of Cortical Processing During Visual Perception and Action

Ray, D.; Hajare, N.; Roy, D.; Banerjee, A.

10.1101/609487 — neuroscience — Posted on 2019-04-16

1432 Short-term evolution under copper stress increases probability of plasmid uptake

Kluemper, U.; Maillard, A.; Hesse, E.; Bayer, F.; van Houte, S.; Longdon, B.; Gaze, W.; Buckling, A.

10.1101/610873 — microbiology — Posted on 2019-04-16

1433 A symbiont phage protein aids in eukaryote immune evasion

Jahn, M. T.; Arkhipova, K.; Markert, S. M.; Stigloher, C.; Lachnit, T.; Pita, L.; Kupczok, A.; Ribes, M.; Stengel, S. T.; Rosenstiel, P.; Dutilh, B. E.; Hentschel, U.

10.1101/608950 — microbiology — Posted on 2019-04-16

1434 Characterizing the molecular and metabolic mechanisms of insecticide resistance in Anopheles gambiae s.l. in Faranah, Guinea

Stica, C.; Jeffries, C. L.; Irish, S. R.; Barry, Y.; Camara, D.; Yansane, I.; Kristan, M.; Walker, T.; Messenger, L.

10.1101/610998 — genetics — Posted on 2019-04-16

1435 An unusual amino acid substitution within the hummingbird cytochrome c oxidase alters a key proton-conducting channel

Dunn, C. D.; Sharma, V.

10.1101/610915 — evolutionary biology — Posted on 2019-04-16

1436 The molecular aetiology of tRNA synthetase depletion: induction of a GCN4 amino acid starvation response despite homeostatic maintenance of charged tRNA levels

McFarland, M. R.; Keller, C. D.; Childers, B. M.; Corrigall, H.; Raguin, A.; Romano, M. C.; Stansfield, I.

10.1101/610790 — systems biology — Posted on 2019-04-16

1437 Intronic heterochromatin prevents cryptic transcription initiation in Arabidopsis

Zhou, J.; Liu, L.; Li, Q.; Xu, W.; Li, K.; Wang, Z.-W.; Sun, Q.

10.1101/610832 — plant biology — Posted on 2019-04-16

1438 Plasma membrane associated Receptor Like Kinases relocalise to plasmodesmata in response to osmotic stress.

Grison, M. S.; Kirk, P.; Brault, M. L.; Wu, X. N.; Schulze, W.; Benitez-Alfonso, Y.; Immel, F.; Bayer, E. E.

10.1101/610881 — plant biology — Posted on 2019-04-16

1439 Mutant MFN2/fzo-1 selectively removes mitochondrial DNA heteroplasmy in Caenorhabditis elegans and in Charcot-Marie-Tooth patients

Meshnik, L.; Bar-Yaacov, D.; Kasztan, D.; Cohen, T.; Kishner, M.; Valenci, I.; Dadon, S.; Klein, C. J.; Vance, J. M.; Nevo, Y.; Zuchner, S.; Mishmar, D.; Ben-Zvi, A.

10.1101/610758 — genetics — Posted on 2019-04-16

1440 YFR016c/Aip5 is part of an actin nucleation complex in budding yeast cells

Glomb, O.; Bareis, L.; Johnsson, N.

10.1101/610980 — cell biology — Posted on 2019-04-16

1441 Impact of physico-chemical parameters on the denitrification and the co-occurrence of Methylophaga nitratireducenticrescens and Hyphomicrobium nitrativorans in a methanol-fed marine denitrifying biofilm

Payette, G.; Geoffroy, V.; Martineau, C.; Villemur, R.

10.1101/602896 — microbiology — Posted on 2019-04-16

1442 Pro-Resolving Mediator Profiles And 5-Lipoxygenase Activity In Cerebrospinal Fluid Correlate with Disease Severity and Outcome in Adults with Tuberculous Meningitis

Colas, R. A.; Le, N. T. H.; Nguyen, T. T. T.; Gomez, E. A.; Ly, L.; Hai, T. H.; Nguyen, P. H.; Nguyen, M. T. H.; Thwaites, G. E.; Dalli, J.

10.1101/608901 — immunology — Posted on 2019-04-16

1443 nf-core: Community curated bioinformatics pipelines

Ewels, P.; Peltzer, A.; Fillinger, S.; Alneberg, J.; Patel, H.; Wilm, A.; Garcia, M.; Di Tommaso, P.; Nahnsen, S.

10.1101/610741 — bioinformatics — Posted on 2019-04-16

1444 Accurate Prediction of Genome-wide RNA Secondary Structure Profile Based On Extreme Gradient Boosting

Ke, Y.; Rao, J.; Zhao, H.; Lu, Y.; Xiao, N.; Yang, Y.

10.1101/610782 — bioinformatics — Posted on 2019-04-16

1445 Within-host competition determines vaccine impact on antibiotic resistance

Davies, N. G.; Flasche, S.; Jit, M.; Atkins, K. E.

10.1101/610188 — evolutionary biology — Posted on 2019-04-16

1446 Cell-projection pumping: A hydrodynamic cell-stiffness dependent mechanism for cytoplasmic transfer between mammalian cells

Zoellner, H.; Paknejad, N.; Cornwell, J.; Chami, B.; Romin, Y.; Boykov, V.; Fujisawa, S.; Kelly, E.; Lynch, G. W.; Rogers, G.; Manova, K.; Moore, M. A.

10.1101/531798 — cell biology — Posted on 2019-04-16

1447 Genotyping-by-sequencing based cytoplasmic markers underpin population structural variation of perennial ryegrass

Cao, M.; Faville, M.; Jacobs, J.; Carena, M.

10.1101/610543 — genetics — Posted on 2019-04-16

1448 Sibe: a computation tool to apply protein sequence statistics to folding and design

Cheung, N. J.; Yu, W.

10.1101/380576 — bioinformatics — Posted on 2019-04-16

1449 Predicting gene expression using morphological cell responses to nanotopography

Cutiongco, M. F.; Jensen, B. S.; Reynolds, P. M.; Gadegaard, N.

10.1101/495879 — bioengineering — Posted on 2019-04-16

1450 Optimized but not maximized cue integration for 3D visual perception

Chang, T.-Y.; Kim, B.; Thompson, L.; Sunkara, A.; Doudlah, R.; Rosenberg, A.

10.1101/611087 — neuroscience — Posted on 2019-04-16

1451 A combination of Interferon Stimulated Genes is more effective than IFNα and IFNss in reducing HIV-1 replication in human cervicovaginal tissues

Rollenhagen, C.; Gui, J.; Doncel, G.; Asin, S. N.

10.1101/610964 — immunology — Posted on 2019-04-16

1452 Synergetic influence of beta-caryophyllene on wound healing

Koyama, S.; Purk, A.; Kaur, M.; Soini, H. A.; Novotny, M. V.; Davis, K.; Kao, C.; Matsunami, H.; Mescher, A.

10.1101/611046 — physiology — Posted on 2019-04-16

1453 Autonomous oscillations and phase-locking in a biophysically detailed model of the STN-GPe network

Koelman, L. A.; Lowery, M. M.

10.1101/611103 — neuroscience — Posted on 2019-04-16

1454 Bi-directional modification of sleep and wake by amyloid beta oligomers

Ozcan, G. G.; Lim, S.; Leighton, P. L. A.; Allison, W. T.; Rihel, J.

10.1101/610014 — neuroscience — Posted on 2019-04-16

1455 The pace of life: Time, temperature, and a biological theory of relativity

Neuheimer, A. B.

10.1101/609446 — ecology — Posted on 2019-04-16

1456 LASSI: A lattice model for simulating phase transitions of multivalent proteins

Choi, J.-M.; Dar, F.; Pappu, R. V.

10.1101/611095 — biophysics — Posted on 2019-04-16

1457 Characterization of aroma-active compounds in delicious apples juices by gas chromatography-mass spectrometry (GC-MS), gas chromatography-olfactometry (GC-O) and odor activity value (OAV)

zhu, j.; Mao, d.; Liu, H.; Li, z.; Niu, y.; Xiao, z.; Zhang, f.

10.1101/611061 — biochemistry — Posted on 2019-04-16

1458 Environmental Assessment of Cytotoxic Drugs in the Oncology Center of Cyprus

Soteriades, E. S.; Economidou, S. C.; Tsivitanidou, A.; Polyviou, P.; Lorimer, A.; Katodritis, N.; Theophanous-Kitiri, S.

10.1101/610931 — pharmacology and toxicology — Posted on 2019-04-16

1459 Post-saccadic face processing is modulated by pre-saccadic preview: Evidence from fixation-related potentials

Buonocore, A.; Dimingen, O.; Melcher, D.

10.1101/610717 — neuroscience — Posted on 2019-04-16

1460 Image processing approaches to enhance perivascular space visibility and quantification using MRI

Sepehrband, F.; Barisano, G.; Sheikh-Bahaei, N.; Cabeen, R. P.; Choupan, J.; Law, M.; Toga, A. W.

10.1101/609362 — neuroscience — Posted on 2019-04-16

1461 Enhanced visuomotor learning and generalization in expert surgeons

Hewitson, C. L.; Kaplan, D. M.

10.1101/611012 — neuroscience — Posted on 2019-04-16

1462 Three-Dimensional Reconstructions of Mouse Circumvallate Taste Buds Using Serial Blockface Scanning Electron Microscopy: I. Cell Types and the Apical Region of the Taste Bud

Yang, R.; Dzowo, Y.; Wilson, C. E.; Russell, R. L.; Kidd, G. J.; Salcedo, E.; Lasher, R. S.; Kinnamon, J. C.; Finger, T. E.

10.1101/610410 — neuroscience — Posted on 2019-04-16

1463 A comprehensive role of Toll-like receptors (TLRs) in diabetic wound healing

Bajpai, S.; Dhayani, A.; Vemula, P. K.; Mishra, R.

10.1101/611053 — immunology — Posted on 2019-04-16

1464 Identification of circular RNAs in porcine spermatozoa and their relation to sperm motility

Godia, M.; Castello, A.; Rocco, M.; Cabrera, B.; Rodriguez-Gil, J. E.; Sanchez, A.; Clop, A.

10.1101/608026 — genomics — Posted on 2019-04-16

1465 COLLECTIVE AGGRESSIVENESS LIMITS COLONY PERSISTENCE IN HIGH BUT NOT LOW ELEVATION SITES IN AMAZONIAN SOCIAL SPIDERS

Lichtenstein, J. L.; Fisher, D. N.; McEwen, B.; Nondorf, D. T.; Calvache, E.; Schmitz, C.; Elasser, J.; Pruitt, J. N.

10.1101/610436 — evolutionary biology — Posted on 2019-04-16

1466 Effects of MCHM on yeast metabolism

Pupo, A.; Ku, K. M.; Gallagher, J.

10.1101/609800 — pharmacology and toxicology — Posted on 2019-04-16

1467 A Porcine Model of Peripheral Nerve Injury Enabling Ultra-Long Regenerative Distances: Surgical Approach, Recovery Kinetics, and Clinical Relevance

Burrell, J. C.; Browne, K. D.; Dutton, J. L.; Das, S.; Brown, D. P.; Laimo, F. A.; Roberts, S.; Petrov, D.; Ali, Z.; Ledebur, H. C.; Rosen, J. M.; Kaplan, H. M.; Wolf, J. A.; Smith, D. H.; Chen, H. I.; Cullen, D. K.

10.1101/610147 — neuroscience — Posted on 2019-04-16

1468 Unique Features of Sub-Cortical Circuits in A Macaque Model of Congenital Blindness

Magrou, L.; Barone, P.; Markov, N. T.; Scheeren, G.; Killackey, H. P.; Giroud, P.; Berland, M.; Knoblauch, K.; Dehay, C.; Kennedy, H.

10.1101/609636 — neuroscience — Posted on 2019-04-16

1469 The outer membrane lipoprotein NlpI nucleates hydrolases within peptidoglycan multi-enzyme complexes in Escherichia coli

Banzhaf, M.; Yau, H. C. L.; Verheul, J.; Lodge, A.; Kritikos, G.; Mateus, A.; Hov, A. K.; Stein, F.; Wartel, M.; Pazos, M.; Solovyova, A. S.; Savitski, M. M.; den Blaauwen, T.; Typas, A.; Vollmer, W.

10.1101/609503 — microbiology — Posted on 2019-04-16

1470 Menace to the ultimate antimicrobials among common Enterobacteriaceae clinical isolates in part of North-East India

Sharma, M.; Chetia, P.; Puzari, M.; Neog, N.; Borah, A.

10.1101/610923 — microbiology — Posted on 2019-04-16

1471 Identifying microbial species by single-molecule DNA optical mapping and resampling statistics

10.1101/609412 — genomics — Posted on 2019-04-16

1472 The more the merrier? Multivariate approaches to genome-wide association analysis

Vroom, C.-R.; de Leeuw, C.; Posthuma, D.; Dolan, C. V.; van der Sluis, S.

10.1101/610287 — genetics — Posted on 2019-04-16

1473 Optimizing genomic prediction of host resistance to koi herpesvirus disease in carp

Palaiokostas, C.; Vesely, T.; Kocour, M.; Prchal, M.; Pokorova, D.; Piackova, V.; Pojezdal, L.; Houston, R. D.

10.1101/609784 — genetics — Posted on 2019-04-16

1474 TRIM21-SERPINB5 aids GMPS repression to protect nasopharyngeal carcinoma cells from radiation-induced apoptosis

Zhang, P.; Li, X.; He, Q.; Zhang, L.; Song, K.; Yang, X.; He, Q.; Wang, Y.; Hong, X.; Ma, J.; Liu, N.

10.1101/609743 — cancer biology — Posted on 2019-04-16

1475 A Deep Learning Approach for Rapid Mutational Screening in Melanoma

Kim, R.; Nomikou, S.; Dawood, Z.; Jour, G.; Donnelly, D.; Moran, U.; Weber, J. S.; Razavian, N.; Snuderl, M.; Shapiro, R.; Berman, R. S.; Coudray, N.; Osman, I.; Tsirigos, A.

10.1101/610311 — pathology — Posted on 2019-04-16

1476 Probing and predicting ganglion cell responses to smooth electrical stimulation in healthy and blind mouse retina

Hoefling, L.; Berens, P.; Zeck, G.

10.1101/609826 — neuroscience — Posted on 2019-04-16

1477 Ca2+-activated K+ channels reduce network excitability, improving adaptability and energetics for transmitting and perceiving sensory information

Li, X.; Abou Tayoun, A.; Song, Z.; Dau, A.; Rien, D.; Jaciuch, D.; Dongre, S.; Blanchard, F.; Nikolaev, A.; Zheng, L.; Bollepalli, M. K.; Chu, B.; Hardie, R. C.; Dolph, P. J.; Juusola, M.

10.1101/476861 — neuroscience — Posted on 2019-04-16

1478 Predicting cognitive and mental health traits and their polygenic architecture using large-scale brain connectomics

Maglanoc, L. A.; Kaufmann, T.; van der Meer, D.; Marquand, A. F.; Wolfers, T.; Jonassen, R.; Hilland, E.; Andreassen, O. A.; Landro, N. I.; Westlye, L. T.

10.1101/609586 — neuroscience — Posted on 2019-04-16

1479 Differential dominance of an allele of the Drosophila tbetah gene challenges standard genetic techniques

Damrau, C.; Eriksson, A.; Colomb, J.; Brembs, B.

10.1101/504332 — genetics — Posted on 2019-04-16

1480 Rapid characterisation of hERG channel kinetics II: temperature dependence

Lei, C. L.; Clerx, M.; Beattie, K. A.; Melgari, D.; Hancox, J.; Gavaghan, D. J.; Polonchuk, L.; Wang, K.; Mirams, G. R.

10.1101/609719 — biophysics — Posted on 2019-04-16

1481 Structural Learning of Proteins Using Graph Convolutional Neural Networks

Zamora-Resendiz, R.; Crivelli, S.

10.1101/610444 — bioinformatics — Posted on 2019-04-16

1482 Spatiotemporally distinct neural mechanisms underlie our reactions to and comparison between value-based options

Froemer, R.; Shenhav, A.

10.1101/609198 — neuroscience — Posted on 2019-04-16

1483 LEMMI: A Live Evaluation of Computational Methods for Metagenome Investigation

Seppey, M.; Manni, M.; Zdobnov, E. M.

10.1101/507731 — microbiology — Posted on 2019-04-16

1484 Effect of heritable symbionts on maternally-derived embryo transcripts

Mateos, M.; Silva, N. O.; Ramirez, P.; Higareda-Alvear, V. M.; Aramayo, R.; Erickson, J. W.

10.1101/607317 — genomics — Posted on 2019-04-16

1485 Common biomarkers of vertebrate senescence respond to age variation in the invertebrate Armadillidium vulgare

Depeux, C.; Samba-Louaka, A.; Becking, T.; Braquart-Varnier, C.; Moreau, J.; Lemaitre, J.-F.; Laverre, T.; Paulhac, H.; Dechaume-Montcharmont, F.-X.; Gaillard, J.-M.; Beltran-Bech, S.

10.1101/583914 — evolutionary biology — Posted on 2019-04-16

1486 Foundress Number, But Not Queen Size Or Boldness, Predicts Colony Life-History In Wild Paper Wasps

Wright, C. M.; Fisher, D. N.; Nerone, W.; Lichtenstein, J. L.; Tibbetts, E.; Pruitt, J. N.

10.1101/609685 — ecology — Posted on 2019-04-16

1487 Balanced nutrient requirements for maize in the Northern Nigerian Savanna: Parameterization and validation of QUEFTS model

Shehu, B. M.; Lawan, B. A.; Jibrin, J. M.; Kamara, A. Y.; Mohammed, I. B.; Rurinda, J.; Zingore, S.; Craufurd, P.; Vanlauwe, B.; Merckx, R.

10.1101/609602 — bioengineering — Posted on 2019-04-16

1488 Arabidopsis glutathione reductase 2 is indispensable in plastids, while mitochondrial glutathione is safeguarded by additional reduction and transport systems

Marty, L.; Bausewein, D.; Müller, C.; Bangash, S. A. K.; Moseler, A.; Schwarzländer, M.; Müller-Schüssele, S. J.; Zechmann, B.; Riondet, C.; Balk, J.; Wirtz, M.; Hell, R.; Reichheld, J.-P.; Meyer, A. J.

10.1101/610477 — plant biology — Posted on 2019-04-16

1489 Inverse Transformed Encoding Models - a solution to the problem of correlated trial-by-trial parameter estimates in fMRI decoding

Soch, J.; Allefeld, C.; Haynes, J.-D.

10.1101/610626 — neuroscience — Posted on 2019-04-16

1490 Reward motivation modulates representation of behaviorally-relevant information across the frontoparietal cortex

Shashidhara, S.; Erez, Y.

10.1101/609537 — neuroscience — Posted on 2019-04-16

1491 Identification of new viruses specific to the honey bee mite Varroa destructor

Herrero, S.; Coll, S.; Gonzalez-Martinez, R. M.; Parenti, S.; Millan-Leiva, A.; Gonzalez-Cabrera, J.

10.1101/610170 — microbiology — Posted on 2019-04-16

1492 Longevity Relatives Count score defines heritable longevity carriers and suggest case improvement in genetic studies

van den Berg, N.; Rodriguez-Girondo, M.; Mandemakers, K.; Janssens, A. A. P. O.; Beekman, M.; Slagboom, P. E.

10.1101/609891 — genetics — Posted on 2019-04-16

1493 Mitogenomic Diversity in Sacred Ibis Mummies sheds light on early Egyptian practices

Wasef, S.; Subramanian, S.; O'Rorke, R.; Huynen, L.; El-Marghani, S.; Curtis, C.; Popinga, A.; Holland, B.; Ikram, S.; Millar, C.; Willerslev, E.; Lambert, D.

10.1101/610584 — evolutionary biology — Posted on 2019-04-16

1494 Altered structural hub connectivity and its clinical relevance in glioma

Douw, L.; Miller, J. J.; Steenwijk, M. D.; Stufflebeam, S. M.; Gerstner, E. R.

10.1101/610618 — cancer biology — Posted on 2019-04-16

1495 Rapid characterisation of hERG channel kinetics I: using an automated high-throughput system

Lei, C. L.; Clerx, M.; Gavaghan, D. J.; Polonchuk, L.; Mirams, G. R.; Wang, K.

10.1101/609727 — biophysics — Posted on 2019-04-16

1496 MAGE-3 peptide amphiphile micelle vaccine promote anti-tumor immunity in mice with stomach cancer.

Windberg, J.; Zhang, R.

10.1101/609214 — bioengineering — Posted on 2019-04-16

1497 VETA: a Matlab toolbox for the collection and analysis of electromyography combined with transcranial magnetic stimulation

Jackson, N.; Greenhouse, I.

10.1101/610386 — physiology — Posted on 2019-04-16

1498 Brown adipocyte NOSEMPE promotes nonmitochondrial thermogenesis and improves systemic metabolism through ATF4 activation

Paulo, E.; Zhang, Y.; Masand, R.; Huynh, T. L.; Seo, Y.; Swaney, D. L.; Soucheray, M.; Jimenez-Morales, D.; Krogan, N. J.; Wang, B.

10.1101/610220 — physiology — Posted on 2019-04-16

1499 Understanding requires tracking: noise and knowledge interact in bilingual comprehension

Blanco-Elorrieta, E.; Ding, N.; Pylkkanen, L.; Poeppel, D.

10.1101/609628 — neuroscience — Posted on 2019-04-16

1500 Accelerated trans-sulfuration metabolically defines a discrete subclass of ALS patients

Gross, S. S.; Chen, Q.; Sandhu, D.; Csaba, K.; Roychoudhury, D.; Schwartz, B. I.; Cheng, R. R.; Bredvik, K.; Kawamata, H.; Calder, E. L.; Studer, L.; Fischer, S. M.; Manfredi, G.

10.1101/609925 — neuroscience — Posted on 2019-04-16

1501 Fermentative Escherichia coli makes a substantial contribution to H2 production in coculture with phototrophic Rhodopseudomonas palustris

Sangani, A. A.; McCully, A. L.; LaSarre, B.; McKinlay, J. B.

10.1101/610568 — microbiology — Posted on 2019-04-16

1502 Upscaling of Microbial Electrolysis Cell Integrating Microbial Electrosynthesis: Insights, Challenges and Perspectives

Tian, J.-H.; Lacroix, R.; Desmond-Le Quemener, E.; Bureau, C.; Midoux, C.; Bouchez, T.

10.1101/609909 — microbiology — Posted on 2019-04-16

1503 Cell-type specific epigenetic links to schizophrenia risk in brain

Mendizabal, I.; Berto, S.; Usui, N.; Toriumi, K.; Chatterjee, P.; Douglas, C.; Huh, I.; Jeong, H.; Layman, T.; Tamminga, C.; Preuss, T.; Konopka, G.; Yi, S.

10.1101/609131 — genomics — Posted on 2019-04-16

1504 Extensive impact of low-frequency variants on the phenotypic landscape at population-scale

Fournier, T.; Abou Saada, O.; Hou, J.; Peter, J.; Caudal, E.; Schacherer, J.

10.1101/609917 — genomics — Posted on 2019-04-16

1505 PyRanges: efficient comparison of genomic intervals in Python

Stovner, E. B.; Saetrom, P.

10.1101/609396 — genomics — Posted on 2019-04-16

1506 RNA-seq analysis of transcriptomes for assessing stress tolerance of S. cerevisiae strain, NCIM3186

Burragoni, S. G.; Ulaganathan, K.

10.1101/609370 — genomics — Posted on 2019-04-16

1507 Evaluation of mitochondrial DNA copy number estimation techniques

Longchamps, R. J.; Castellani, C. A.; Newcomb, C. E.; Sumpter, J. A.; Lane, J.; Grove, M. L.; Guallar, E.; Pankratz, N.; Taylor, K. D.; Rotter, J. I.; Boerwinkle, E.; Arking, D.

10.1101/610238 — genetics — Posted on 2019-04-16

1508 Inhibition of Lipin lipid phosphatase hyperactivity rescues TorsinA neurological disease

Cascalho, A.; Foroozandeh, J.; Hennebel, L.; Klein, C.; Rous, S.; Gonzalez, B. D.; Pisani, A.; Meringolo, M.; Gallego, S. F.; Verstreken, P.; Seibler, P.; Goodchild, R. E.

10.1101/606947 — genetics — Posted on 2019-04-16

1509 Predicting the short-term success of human influenza A variants with machine learning

Hayati, M.; Biller, P.; Colijn, C.

10.1101/609248 — evolutionary biology — Posted on 2019-04-16

1510 Accumulation and purging of deleterious mutations through severe bottlenecks in ibex

Grossen, C.; Guillaume, F.; Keller, L. F.; Croll, D.

10.1101/605147 — evolutionary biology — Posted on 2019-04-16

1511 Imperfect strategy transmission can reverse the role of population viscosity on the evolution of altruism

Debarre, F.

10.1101/609818 — evolutionary biology — Posted on 2019-04-16

1512 Within-host competition determines vaccine impact on antibiotic resistance

Davies, N. G.; Flasche, S.; Jit, M.; Atkins, K. E.

10.1101/610188 — evolutionary biology — Posted on 2019-04-16

1513 Fitness effects of host-bacterial interactions - the microbial perspective

Deines, P.; Hammerschmidt, K.; Bosch, T. C.

10.1101/609271 — ecology — Posted on 2019-04-16

1514 PIKfyve deficiency in myeloid cells impairs lysosomal homeostasis in macrophages and promotes systemic inflammation in mice

Min, S. H.; Suzuki, A.; Weaver, L.; Guzman, J.; Zhao, L.; Gonzalez, F.; Spruce, L. A.; Seeholzer, S. H.; Behrens, E. M.; Abrams, C. S.

10.1101/610683 — cell biology — Posted on 2019-04-16

1515 FIGARO: An efficient and objective tool for optimizing microbiome rRNA gene trimming parameters

Weinstein, M. M.; Prem, A.; Jin, M.; Tang, S.; Bhasin, J. M.

10.1101/610394 — bioinformatics — Posted on 2019-04-16

1516 Biodistribution and inflammatory response of intracranial delivery of scintillating nanoparticles

Fischer, M.; Zimmerman, A.; Zhang, E.; Kolis, J.; Dickey, A.; Burdette, M. K.; Afaghpour-Becklund, M.; Chander, P.; Foulger, S.; Brigman, J.; Weick, J.

10.1101/609354 — bioengineering — Posted on 2019-04-16

1517 Progress toward the identification and stacking of crucial domestication traits in pennycress

Chopra, R.; Johnson, E. B.; Emenecker, R.; Cahoon, E.; Lyons, J.; Kliebenstein, D. J.; Daniels, E.; Dorn, K.; Esfahanian, M.; Folstad, N.; Frels, K.; McGinn, M.; Ott, M.; Gallaher, C.; Altendorf, K.; Berroyer, A.; Ismail, B.; Anderson, J. A.; Wyse, D. L.; Umaslov, T.; Sedbrook, J. C.; Marks, M. D.

10.1101/609990 — plant biology — Posted on 2019-04-16

1518 Routing of non-mnemonic hippocampal ripples to subcortical structures

Tingley, D.; Buzsaki, G.

10.1101/610402 — neuroscience — Posted on 2019-04-16

1519 Caenorhabditis elegans sensory neurons modulate pathogen specific responses via HLH-30/TFEB transcription factor and FSHR-1 GPCR axes of immunity

Gupta, A.; Varma, M. M.; Singh, V.

10.1101/609610 — immunology — Posted on 2019-04-16

1520 Maturation of naïve and antigen-experienced B-cell receptor repertoires with age

Ghraichy, M.; Galson, J. D.; Kovaltsuk, A.; von Niederhaeusern, V.; Pachlopnik Schmid, J.; Miho, E.; Kelly, D. F.; Deane, C. M.; Trueck, J.

10.1101/609651 — immunology — Posted on 2019-04-16

1521 Cyclin B3 is dispensable for mouse spermatogenesis

Karasu, M. E.; Keeney, S.

10.1101/608315 — genetics — Posted on 2019-04-16

1522 The ecological and epidemiological consequences of reproductive interference between the vectors Aedes aegypti and Aedes albopictus

Paton, R. S.; Bonsall, M.

10.1101/610451 — ecology — Posted on 2019-04-16

1523 Methods for the generation of heritable germline mutations in the disease vector Culex quinquefasciatus using CRISPR/Cas9.

Li, M.; Li, T.; Liu, N.; Raban, R.; Wang, X.; Akbari, O.

10.1101/609206 — bioengineering — Posted on 2019-04-16

1524 The number sense is an emergent property of a deep convolutional neural network trained for object recognition

DeWind, N. K.

10.1101/609347 — animal behavior and cognition — Posted on 2019-04-16

1525 Stem cell delivery to kidney via minimally invasive ultrasound-guided renal artery injection in mice

Zaw Thin, M.; Ogunldade, O.; Comenge, J.; Patrick, P. S.; Stuckey, D. J.; David, A. L.; Levy, R.; Lythgoe, M. F.; Beard, P.; Kalber, T. L.

10.1101/609230 — cell biology — Posted on 2019-04-16

1526 Mechanical constraints influence microtubule orientation in plant cells

Bachmann, S.; Froese, R.; Cytrynbaum, E.

10.1101/609867 — cell biology — Posted on 2019-04-16

1527 The Maize LINC KASH AtSINE-like2 (MLKS2) gene encodes an ARM domain protein that tethers the nucleus to F-actin and is required for normal development and meiotic chromosome segregation

Gumber, H. K.; McMenna, J. F.; Tolmie, A. F.; Jalovec, A. M.; Kartick, A. C.; Graumann, K.; Bass, H. W.

10.1101/609594 — cell biology — Posted on 2019-04-16

1528 Growth-dependent activation of protein kinases links cell cycle progression to cell growth

Jasani, A.; Huynh, T.; Kellogg, D.

10.1101/610469 — cell biology — Posted on 2019-04-16

1529 Lineage specific core-regulatory circuits determine gene essentiality in cancer cells

Rauscher, B.; Henkel, L.; Heigwer, F.; Boutros, M.

10.1101/609552 — systems biology — Posted on 2019-04-16

1530 Relationship between Dynamic Instability of Individual Microtubules and Flux of Subunits into and out of Polymer

Mauro, A. J.; Jonasson, E. M.; Goodson, H. V.

10.1101/609701 — biophysics — Posted on 2019-04-16

1531 Selective Prespacer Processing Ensures Precise CRISPR-Cas Adaptation

Kim, S.; Loeff, L.; Colombo, S.; Brouns, S.; Joo, C.

10.1101/608976 — biophysics — Posted on 2019-04-16

1532 Rapid characterisation of hERG channel kinetics I: using an automated high-throughput system

Lei, C. L.; Clerx, M.; Gavaghan, D. J.; Polonchuk, L.; Mirams, G. R.; Wang, K.

10.1101/609727 — biophysics — Posted on 2019-04-16

1533 A 3D molecular atlas of the chick embryonic heart

Anderson, C.; Hill, B.; Lu, H.-C.; Moverley, A.; Yang, Y.; Oliveira, N. M. M.; Baldock, R. A.; Stern, C. D.

10.1101/609032 — developmental biology — Posted on 2019-04-16

1534 Rapid characterisation of hERG channel kinetics II: temperature dependence

Lei, C. L.; Clerx, M.; Beattie, K. A.; Melgari, D.; Hancox, J.; Gavaghan, D. J.; Polonchuk, L.; Wang, K.; Mirams, G. R.

10.1101/609719 — biophysics — Posted on 2019-04-16

1535 Four ways to fit an ion channel model

Clerx, M.; Beattie, K. A.; Gavaghan, D. J.; Mirams, G. R.

10.1101/609875 — biophysics — Posted on 2019-04-16

1536 Network modelling of Epithelial-to-Mesenchymal transition reveals a putative role of RPTPs for the control of metastasis.

Pais, R. J.

10.1101/609263 — systems biology — Posted on 2019-04-15

1537 Amelioration of muscular dystrophy phenotype in mdx mice by inhibition of Flt1

Verma, M.; Shimizu-Motohashi, Y.; Asakura, Y.; Ennen, J.; Bosco, J.; Zou, Z.; Fong, G.-H.; Josiah, S.; Keefe, D.; Asakura, A.

10.1101/609735 — developmental biology — Posted on 2019-04-15

1538 TLR4-dependent signaling drives extracellular catabolism of low-density lipoprotein aggregates

Singh, R. K.; Haka, A. S.; Asmal, A.; Barbosa-Lorenzi, V. C.; Grosheva, I.; Chin, H. F.; Xiong, Y.; Hla, T.; Maxfield, F. R.

10.1101/610162 — cell biology — Posted on 2019-04-15

1539 A single K+-binding site in the crystal structure of the gastric proton pump

Yamamoto, K.; Dubey, V.; Irie, K.; Nakanishi, H.; Khandelia, H.; Fujiyoshi, Y.; Abe, K.

10.1101/608851 — biochemistry — Posted on 2019-04-15

1540 Prevalence and risk factors of postpartum depression within one year after birth in urban slums of Dhaka, Bangladesh

Azad, R.; Fahmi, R.; Shrestha, S.; Joshi, H.; Hasan, M.; Khan, A. N. S.; Chowdhury, M. A. K.; Arifeen, S. E.; Billah, S. M.

10.1101/514729 — epidemiology — Posted on 2019-04-15

1541 Alternative pathway androgen biosynthesis and human fetal female virilization

Reisch, N.; Taylor, A. E.; Nogueiras, E. F.; Asby, D. J.; Dhir, V.; Berry, A.; Krone, N. P.; Auchus, R. J.; Shackleton, C. H.; Hanley, N. A.; Arlt, W.

10.1101/609289 — developmental biology — Posted on 2019-04-15

1542 miR-9 mediated noise optimization of the her6 oscillator is needed for cell state progression in the Zebrafish hindbrain

Soto, X.; Biga, V.; Kursawe, J.; Lea, R.; Doostdar, P.; Papalopulu, N.

10.1101/608604 — developmental biology — Posted on 2019-04-15

1543 HNF4 factors control chromatin accessibility and are redundantly required for maturation of the fetal intestine

Chen, L.; Toke, N. H.; Luo, S.; Vasoya, R. P.; Aita, R.; Parthasarathy, A.; Tsai, Y.-H.; Spence, J. R.; Verzi, M. P.

10.1101/610428 — developmental biology — Posted on 2019-04-15

1544 Scale-free Vertical Tracking Microscopy: Towards Bridging Scales in Biological Oceanography

Krishnamurthy, D.; Li, H.; Benoit du Rey, F.; Cambournac, P.; Larson, A.; Prakash, M.

10.1101/610246 — biophysics — Posted on 2019-04-15

1545 A programmable DNA-origami platform for studying protein-mediated lipid transfer between bilayers

Bian, X.; Zhang, Z.; De Camilli, P.; Lin, C.

10.1101/610212 — biochemistry — Posted on 2019-04-15

1546 Learning-accelerated Discovery of Immune-Tumour Interactions

Ozik, J.; Collier, N.; Heiland, R.; Macklin, P.

10.1101/573972 — systems biology — Posted on 2019-04-15

1547 COMICS: A pipeline for the composite identification of selection across multiple genomic scans using Invariant Coordinate Selection in R

Nelson, J. T.; Cornejo, O. E.

10.1101/587469 — bioinformatics — Posted on 2019-04-15

1548 Systematic and comprehensive benchmarking of an exome sequencing based germline copy-number variant detection pipeline to detect clinically relevant CNVs

Rajagoapalan, R.; Murrell, J.; Luo, M.; Conlin, L. K.

10.1101/579755 — bioinformatics — Posted on 2019-04-15

1549 Sequence-Dependent DNA Shape Features Regulate Chromatin Accessibility in Alternatively Activated Macrophages

Tang, M. S.; Miraldi, E. R.; Girgis, N. M.; Bonneau, R. A.; Loke, P.

10.1101/327023 — immunology — Posted on 2019-04-15

1550 Monocarboxylate Transport In Drosophila Larval Brain During Low And High Neuronal Activity

Gonzalez-Gutierrez, A.; Ibacache, A.; Esparza, A.; Barros, L. F.; Sierralta, J.

10.1101/610196 — neuroscience — Posted on 2019-04-15

1551 U-PASS: unified power analysis and forensics for qualitative traits in genetic association studies

Gao, Z.; Terhorst, J.; Van Hout, C.; Stoev, S.

10.1101/605766 — genetics — Posted on 2019-04-15

1552 Modeling unitary fields and the single neuron contribution to local field potentials in the hippocampus

Telenczuk, M.; Telenczuk, B.; Destexhe, A.

10.1101/602953 — neuroscience — Posted on 2019-04-15

1553 Linking molecular pathways and large-scale computational modeling to assess candidate disease mechanisms and pharmacodynamics in Alzheimer’s disease

Stefanovski, L.; Triebkorn, P.; Spiegler, A.; Diaz-Cortes, M.-A.; Solodkin, A.; Jirsa, V.; McIntosh, R.; Ritter, P.; The Alzheimer's Disease Neuroimaging Initiative,

10.1101/600205 — neuroscience — Posted on 2019-04-15

1554 VariCarta: a comprehensive database of harmonized genomic variants found in ASD sequencing studies

Belmadani, M.; Jacobson, M.; Holmes, N.; Phan, M.; Pavlidis, P.; Rogic, S.

10.1101/608356 — genomics — Posted on 2019-04-15

1555 Mitofusin 2 regulates neutrophil adhesive migration via suppressing Rac activation

Zhou, W.; Hsu, A. Y.; Wang, T.; Jeffries, J.; Mohammad, H. T.; Wang, X.; Umulis, D. M.; Seleem, M. N.; Deng, Q.

10.1101/608091 — cell biology — Posted on 2019-04-15

1556 Misfolded Amyloid β-42 induced impairment of the endo-lysosomal pathway revealed by real-time optical monitoring

Marshall, K.; Vadukul, D.; Staras, K.; Serpell, L.

10.1101/598540 — neuroscience — Posted on 2019-04-15

1557 Microtubules coordinate protrusion-retraction dynamics in migrating dendritic cells

Kopf, A.; Renkawitz, J.; Hauschild, R.; Girkontaite, I.; Tedford, K.; Merrin, J.; Thorn-Seshold, O.; Trauner, D.; Haecker, H.; Fischer, K. D.; Kiermaier, E.; Sixt, M.

10.1101/609420 — cell biology — Posted on 2019-04-15

1558 Initiation of chromosome replication controls both division and replication cycles in E. coli through a double-adder mechanism

Witz, G.; van Nimwegen, E.; Julou, T.

10.1101/593590 — systems biology — Posted on 2019-04-15

1559 Rapid and dynamic nucleic acid hybridization enables enzymatic oligonucleotide synthesis by cyclic reversible termination

Hoff, K.; Halpain, M.; Garbagnati, G.; Edwards, J.; Zhou, W.

10.1101/561092 — synthetic biology — Posted on 2019-04-15

1560 Mapping and dynamics of regulatory DNA in maturing seeds

Sullivan, A. M.; Arsovski, A. A.; Thompson, A.; Sandstrom, R.; Thurman, R. E.; Neph, S.; Johnson, A. K.; Sullivan, S. T.; Sabo, P. J.; Neri, F. V.; Weaver, M.; Diegel, M.; Nemhauser, J. L.; Stamatoyannopoulos, J. A.; Bubb, K. L.; Queitsch, C.

10.1101/235325 — plant biology — Posted on 2019-04-15

1561 Pre-Settlement Forests around Puget Sound: Eyewitness Evidence

Schroeder, T.

10.1101/592733 — plant biology — Posted on 2019-04-15

1562 Dendritic spines on GABAergic neurons respond to cholinergic signaling in the Caenorhabditis elegans motor circuit.

Cuentas-Condori, A. A.; Mulcahy, B.; He, S.; Palumbos, S.; Zhen, M.; Miller, D. M.

10.1101/598714 — neuroscience — Posted on 2019-04-15

1563 Presynaptic MAST Kinase Controls Bidirectional Post-SynapticResponses to Convey Stimulus Valence in C. elegans

Nakano, S.; Ikeda, M.; Tsukada, Y.; Fei, X.; Suzuki, T.; Ahluwalia, R.; Sano, A.; Kondo, R.; Ihara, K.; Hashimoto, K.; Higashiyama, T.; Mori, I.

10.1101/609479 — neuroscience — Posted on 2019-04-15

1564 Interspecies signaling generates exploratory motility in Pseudomonas aeruginosa

Limoli, D. H.; Donegan, N. P.; Warren, E. A.; Cheung, A. L.; O'Toole, G.

10.1101/607523 — microbiology — Posted on 2019-04-15

1565 A Probabilistic Programming Approach to Protein Structure Superposition

Sanz Moreta, L.; Al-Sibahi, A. S. S.; Hamelryck, T.; Theobald, D.; Rommes, B. N.; Bullock, W.; Manoukian, A.

10.1101/575431 — bioinformatics — Posted on 2019-04-15

1566 Developmentally regulated Shh expression is robust to TAD perturbations

Williamson, I.; Kane, L.; Devenney, P. S.; Anderson, E.; Kilanowski, F.; Hill, R. E.; Bickmore, W.; Lettice, L.

10.1101/609941 — developmental biology — Posted on 2019-04-15

1567 ColiCoords: A Python package for the analysis of bacterial fluorescence microscopy data

Smit, J. H.; Yichen, L.; Warszawik, E. M.; Herrmann, A.; Cordes, T.

10.1101/608109 — bioinformatics — Posted on 2019-04-15

1568 Deleterious in late life mitochondrial alleles and aging: secrets of Japanese centenarians

Mikhailova, A.; Shamansky, V.; Bazykin, G. A.; Mazunin, I.; Gunbin, K.; Kunz, W.; Reymond, A.; Tanaka, M.; Khrapko, K.; Popadin, K.

10.1101/603282 — genetics — Posted on 2019-04-15

1569 Latent Space Phenotyping: Automatic Image-Based Phenotyping for Treatment Studies

Ubbens, J. R.; Cieslak, M.; Prusinkiewicz, P.; Stavness, I.

10.1101/557678 — plant biology — Posted on 2019-04-15

1570 Single cell transcriptomics is a robust approach to defining disease biology in complex clinical settings.

Kort, E. J.; Weiland, M.; Grins, E.; Eugster, E.; Milliron, H.-y.; Kelty, C.; Shrestha, N. M.; Timek, T.; Leacche, M.; Fitch, S.; Boeve, T.; Marco, G.; Dickinson, M.; Wilton, P.; Jovinge, S.

10.1101/568659 — genomics — Posted on 2019-04-15

1571 CD8+ lymphocytes modulate Zika virus dynamics and tissue dissemination and orchestrate antiviral immunity

Schouest, B.; Fahlberg, M.; Scheef, E. A.; Ward, M. J.; Headrick, K.; Szeltner, D. M.; Blair, R. V.; Gilbert, M. H.; Doyle-Meyers, L. A.; Danner, V. W.; Bonaldo, M. C.; Wesson, D. M.; Panganiban, A. T.; Maness, N. J.

10.1101/475418 — immunology — Posted on 2019-04-15

1572 Robust and Interpretable PAM50 Reclassification Exhibits Survival Advantage for Myoepithelial and Immune Phenotypes

Mathews, J.; Nadeem, S.; Levine, A. J.; Pouryahya, M.; Deasy, J. O.; Tannenbaum, A.

10.1101/480723 — cancer biology — Posted on 2019-04-15

1573 Mutual regulation underlies paralogue functional diversification

Gurska, D.; Vargas Jentzsch, I. M.; Panfilio, K. A.

10.1101/427245 — evolutionary biology — Posted on 2019-04-15

1574 Prioritize diversity or declining species? Trade-offs and synergies in spatial planning for the conservation of migratory birds in the face of land cover change

Wilson, S.; Schuster, R.; Rodewald, A.; Bennett, J.; Smith, A.; La Sorte, F.; Verburg, P.; Arcese, P.

10.1101/429019 — ecology — Posted on 2019-04-15

1575 Behaviors of individual microtubules and microtubule populations relative to critical concentrations: Dynamic instability occurs when critical concentrations are driven apart by nucleotide hydrolysis

Jonasson, E. M.; Mauro, A. J.; Li, C.; Norby, E. C.; Mahserejian, S. M.; Scripture, J. P.; Gregoretti, I. V.; Alber, M. S.; Goodson, H.

10.1101/260646 — cell biology — Posted on 2019-04-15

1576 The thin edge of the wedge: extremely high extinction risk in wedgefishes and giant guitarfishes

Kyne, P. M.; Jabado, R. W.; Rigby, C. L.; Dharmadi, ; Gore, M. A.; Pollock, C. M.; Herman, K. B.; Cheok, J.; Ebert, D. A.; Simpfendorfer, C. A.; Dulvy, N. K.

10.1101/595462 — ecology — Posted on 2019-04-15

1577 Mck1 defines a key S-phase checkpoint effector in response to various degrees of replication threats

Li, X.; Jin, X.; Sharma, S.; Liu, X.; Zhang, J.; Niu, Y.; Li, J.; Li, Z.; Zhang, J.; Cao, Q.; Liu, B.; Lou, H.

10.1101/610105 — molecular biology — Posted on 2019-04-15

1578 Transcriptomic profiling of Streptococcus pyogenes M1T1 strain in a mouse model of necrotizing fasciitis

Hirose, Y.; Yamaguchi, M.; Okuzaki, D.; Motooka, D.; Hamamoto, H.; Hanada, T.; Sumitomo, T.; Nakata, M.; Kawabata, S.

10.1101/610139 — microbiology — Posted on 2019-04-15

1579 Human Chrysomya bezziana myiasis: A systematic review

Zhou, X.; Kambalame, D. M.; Zhou, S.; Guo, X.; Xia, D.; Yang, Y.; Wu, R.; Luo, J.; Jia, F.; Yuen, M.; Xu, Y.; Dai, G.; Li, L.; Xie, T.; Puthiyakunnon, S.; Wei, W.; Xie, L.; Liang, S.; Feng, Y.; Huang, S.; Hu, Y.; Mo, Q.; Mai, R.; Zhang, X.; Spradbery, P.; Zhou, X.

10.1101/610121 — epidemiology — Posted on 2019-04-15

1580 Oleocanthal and oleocanthal-rich olive oils induce lysosomal membrane permeabilization in cancer cells

Goren, L.; Zhang, G.; Kaushik, S.; Breslin, P. A.; Du, Y.-C. N.; Foster, D. A.

10.1101/610097 — cancer biology — Posted on 2019-04-15

1581 Epidemiology of drug-resistant tuberculosis in Chongqing, China: a retrospective observational study from 2010 to 2017

Wu, B.; Yu, Y.; Du, C.; Liu, Y.; Hu, D.

10.1101/610048 — epidemiology — Posted on 2019-04-15

1582 Detrital Food Web Drives Aquatic Ecosystem Productivity in a Seasonally Inundated Managed Floodplain

Jeffres, C.; Holmes, E. J.; Sommer, T. R.; Katz, J. V. E.

10.1101/610055 — ecology — Posted on 2019-04-15

1583 Projected climate change will reduce habitat suitability for bumble bees in the Pacific Northwest

Koch, J.; Looney, C.; Hopkins, B.; Lichtenberg, E. M.; Sheppard, W. S.; Strange, J. P.

10.1101/610071 — ecology — Posted on 2019-04-15

1584 Transmission of prion infectivity from blood by peptoid-conjugated beads

Hornemann, S.; Schwarz, P.; Rushing, E. J.; Connolly, M. D.; Zuckermann, R. N.; Yam, A. Y.; Aguzzi, A.

10.1101/609966 — neuroscience — Posted on 2019-04-15

1585 Promotion of adipogenesis by JMJD6 requires the AT hook-like domain and is independent of its catalytic function

Reyes-Gutierrez, P.; Carrasquillo-Rodriguez, J. W.; Imbalzano, A. N.

10.1101/609982 — molecular biology — Posted on 2019-04-15

1586 Use of an automated pyrosequencing technique for confirmation of Sickle Cell Disease

Martino, C. C.; Alencar, C. S.; Loureiro, P.; Carneiro-Proietti, A. B. d. F.; Maximo, C. d. A.; Mota, R. A.; Gaburo Junior, N.; Kelly, S.; Sabino, E. C.; nternational Component of the NHLBI Recipient Epid,

10.1101/610063 — molecular biology — Posted on 2019-04-15

1587 Evidence for Early European Neolithic Dog Dispersal: New Data on South-Eastern European subfossil dogs from Prehistory and Antiquity Ages

Radoslavov, G.; Marinov, M.; Yankova, I.; Neov, B.; Petrova, M.; Spassov, N.; Hristov, P.

10.1101/609974 — evolutionary biology — Posted on 2019-04-15

1588 Number of days required to estimate objectively measured physical activity constructs in different age groups

Ricardo, L.; Wendt, A.; Galliano, L.; de Andrade Muller, W.; Nino Cruz, G.; C. Wehrmeister, F.; Brage, S.; Ekelund, U.; Crochemore M Silva, I.

10.1101/610030 — epidemiology — Posted on 2019-04-15

1589 Identification of Gly/NMDAR Antagonist from Chromolaena odoratas Derived Phytoconstituents using Induced Fit Docking Approach.

David, I. T.; Omotuyi, O.; Agboola, O.; Okonkwo, D.; Adelakun, N.

10.1101/610006 — bioinformatics — Posted on 2019-04-15

1590 Biofluid modeling of the coupled eye-brain system and insights into simulated microgravity conditions

Salerni, F.; Repetto, R.; Harris, A.; Pinsky, P.; Prud'homme, C.; Szopos, M.; Guidoboni, G.

10.1101/609958 — physiology — Posted on 2019-04-15

1591 Integrating Protein Localization with Automated Signaling Pathway Reconstruction

Youssef, I.; Law, J.; Ritz, A.

10.1101/609149 — bioinformatics — Posted on 2019-04-15

1592 Noninvasive prenatal diagnosis for Hemophilia A by haplotype-based approach using cell-free fetal DNA in maternal plasma

He, Z.; Chen, C.; Guo, F.; Jiang, L.; Zhu, Y.; Li, D.; Wu, R.; Lu, R.; Zhao, M.; Chen, F.; Ni, P.; Jiang, W.; Sun, J.; Peng, Z.

10.1101/563429 — molecular biology — Posted on 2019-04-15

1593 Functional Profiling of Single CRISPR/Cas9-Edited Human Long-Term Hematopoietic Stem Cells

Wagenblast, E.; Azkanaz, M.; Smith, S. A.; Shakib, L.; McLeod, J. L.; Krivdova, G.; Shultz, L. D.; Gan, O. I.; Dick, J. E.; Lechman, E. R.

10.1101/609040 — genetics — Posted on 2019-04-15

1594 Rare variants contribute disproportionately to quantitative trait variation in yeast

Bloom, J. S.; Boocock, J.; Treusch, S.; Sadhu, M. J.; Day, L.; Oates-Barker, H.; Kruglyak, L.

10.1101/607291 — genetics — Posted on 2019-04-15

1595 Neogenin-1 distinguishes between myeloid-biased and balanced Hoxb5+ long-term hematopoietic stem cells

Gulati, G. S.; Zukowska, M.; Noh, J.; Zhang, A.; Sinha, R.; George, B.; Wesche, D.; Weissman, I. L.; Szade, K.

10.1101/608398 — cell biology — Posted on 2019-04-15

1596 Integrative analysis identifies key molecular signatures underlying neurodevelopmental deficits in Fragile X Syndrome

Utami, K. H.; Skotte, N. H.; Colaco, A. R.; Yusof, N. A. B. M.; Sim, B.; Yeo, X. Y.; Bae, H.-G.; Garcia-Miralles, M.; Radulescu, C. I.; Chen, Q.; Chaldaiopoulou, G.; Liany, H.; Nama, S.; Sampath, P.; Jung, S.; Mann, M.; Pouladi, M. A.

10.1101/606038 — neuroscience — Posted on 2019-04-15

1597 Development of specific molecular markers to distinguish and quantify broomrape species in a soil sample from infected field

Aly, R.; Bari, V. K.; Londner, A.; Nassar, J. A.; Salaime, L. T.; Eizenberg, H.; Lati, R.

10.1101/602284 — molecular biology — Posted on 2019-04-15

1598 A Bayesian decomposition of BAC firing as a mechanism for apical amplification in neocortical pyramidal neurons

Kay, J.; Phillips, W.; Aru, J.; Graham, B.; Larkum, M.

10.1101/604066 — neuroscience — Posted on 2019-04-15

1599 Multi-model inference of non-random mating from an information theoretic approach

Carvajal-Rodriguez, A.

10.1101/305730 — evolutionary biology — Posted on 2019-04-15

1600 Evolved phenological cueing strategies show variable responses to climate change

Edwards, C. B.; Yang, L.

10.1101/436857 — ecology — Posted on 2019-04-15

1601 Human influences on antipredator behavior in Darwin’s finches

Gotanda, K. M.

10.1101/591651 — animal behavior and cognition — Posted on 2019-04-15

1602 ETFL: A formulation for flux balance models accounting for expression, thermodynamics, and resource allocation constraints

Salvy, P.; Hatzimanikatis, V.

10.1101/590992 — systems biology — Posted on 2019-04-15

1603 Understand human olfactory ecology and the methodological challenges in field-testing olfactory ability

Hoover, K. C.; Botescu, D.; Fedurek, P.; Roberts, J.; Aarts, S.; Berbesque, J. C.

10.1101/270744 — ecology — Posted on 2019-04-15

1604 Anhedonia following mild traumatic brain injury in rats: A behavioral economic analysis of positive and negative reinforcement

Avcu, P.; Fortress, A. M.; Fragale, J. E.; Spiegler, K.; Pang, K.

10.1101/527895 — animal behavior and cognition — Posted on 2019-04-15

1605 Stasimon contributes to the loss of sensory synapses and motor neuron death in a mouse model of spinal muscular atrophy

Simon, C. M.; Van Alstyne, M.; Lotti, F.; Bianchetti, E.; Tisdale, S.; Mentis, G. Z.; Pellizzoni, L.

10.1101/608513 — neuroscience — Posted on 2019-04-15

1606 The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function.

Ward, J.; Tunbridge, E. M.; Sandor, C.; Lyall, L.; Ferguson, A.; Strawbridge, R. J.; Lyall, D. M.; Cullen, B.; Graham, N.; Johnston, K. J. A.; Webber, C.; Escott-Price, V.; O'Donovan, M. P.; Pell, J. P.; Bailey, M. E. S.; Harrison, P. J.; Smith, D. J.

10.1101/549931 — genetics — Posted on 2019-04-15

1607 Socio-behavioural characteristics and HIV: findings from a causal modelling analysis of 29 sub-Saharan African countries

Baranczuk, Z.; Estill, J.; Blough, S.; Meier, S.; Merzouki, A.; Maathuis, M. H.; Keiser, O.

10.1101/600510 — epidemiology — Posted on 2019-04-15

1608 Anthropogenic risk factors as the major cause of cancer driver events

Belikov, A. V.

10.1101/486860 — cancer biology — Posted on 2019-04-15

1609 A backward encoding approach to recover subcortical auditory activity

Schmidt, F.; Demarchi, G.; Geyer, F.; Weisz, N.

10.1101/606251 — neuroscience — Posted on 2019-04-15

1610 A dynamical model of the laminar BOLD response

Havlicek, M.; Uludag, K.

10.1101/609099 — neuroscience — Posted on 2019-04-15

1611 The personalized temporal dynamics of microbiome in the airways of cystic fibrosis patients

Bacci, G.; Taccetti, G.; Dolce, D.; Armanini, F.; Segata, N.; Di Cesare, F.; Lucidi, V.; Fiscarelli, E. V.; Morelli, P.; Casciaro, R.; Negroni, A.; Mengoni, A.; Bevivino, A.

10.1101/609057 — microbiology — Posted on 2019-04-15

1612 Streptococcus pyogenes capsule promotes microcolony-independent biofilm formation

Matysik, A.; Kline, K.

10.1101/609065 — microbiology — Posted on 2019-04-15

Hu, Z.; Wang, C.; Zhang, E.; Wang, X.; Xu, Y.; Chang, Y.; Ju, S.; Yang, L.; Qian, Q.; Chen, Y.; Chen, S.; Qin, N.; Ma, Z.; Dai, J.; Ma, H.; Jin, G.

10.1101/608877 — genomics — Posted on 2019-04-15

1614 Targeted expansion of Protected Areas to maximise the persistence of terrestrial mammals

Mogg, S.; Fastre, C.; Visconti, P.

10.1101/608992 — ecology — Posted on 2019-04-15

1615 Robust Reconstruction of CRISPR and Tumor Lineage Using Depth Metrics

Sugino, K.; Lee, T.

10.1101/609107 — developmental biology — Posted on 2019-04-15

1616 Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells

Garcin, E. B.; Gon, S.; Prakash, R.; Sullivan, M. R.; Brunette, G. J.; De Cian, A.; Concordet, J.-P.; Giovannangeli, C.; Dirks, W. G.; Eberth, S.; Bernstein, K. A.; Jasin, M.; Modesti, M.

10.1101/609115 — cell biology — Posted on 2019-04-15

1617 The Drosophila Afadin and ZO-1 homologs Canoe and Polychaetoid act in parallel to maintain epithelial integrity when challenged by adherens junction remodeling

Manning, L.; Perez-Vale, K.; Schaefer, K.; Sewell, M.; Peifer, M.

10.1101/609123 — cell biology — Posted on 2019-04-15

1618 Detection of introduced and resident marine species using environmental DNA metabarcoding of sediment and water

Holman, L. E.; de Bruyn, M.; Creer, S.; Carvalho, G.; Robidart, J.; Rius, M.

10.1101/440768 — molecular biology — Posted on 2019-04-15

1619 Nonlinear Effects of Intraspecific Competition Alter Landscape-Wide Upscaling of Ecosystem Function

Little, C. J.; Fronhofer, E. A.; Altermatt, F.

10.1101/470591 — ecology — Posted on 2019-04-15

1620 A glucose-dependent spatial patterning of exocytosis inhuman β-cells is disrupted in type 2 diabetes

Fu, J.; Githaka, J. M.; Dai, X.; Plummer, G.; Suzuki, K.; Spigelman, A. F.; Bautista, A.; Kim, R.; Greitzer-Antes, D.; Manning Fox, J. E.; Gaisano, H. Y.; MacDonald, P. E.

10.1101/534669 — cell biology — Posted on 2019-04-15

1621 Generation of viral vectors specific to neuronal subtypes of targeted brain regions by Enhancer-Driven Gene Expression (EDGE)

Nair, R. R.; Blankvoort, S.; Lagartos, M. J.; Kentros, C.

10.1101/606467 — neuroscience — Posted on 2019-04-15

1622 Analysis of miniaturization effects and channel selection strategies for EEG sensor networks with application to auditory attention detection

Mundanad Narayanan, A.; Bertrand, A.

10.1101/593194 — neuroscience — Posted on 2019-04-15

1623 EMULSION: transparent and flexible multiscale stochastic models in epidemiology

Picault, S.; Huang, Y.-L.; Sicard, V.; Arnoux, S.; Beaunee, G.; Ezanno, P.

10.1101/563791 — epidemiology — Posted on 2019-04-15

1624 The ELIXIR Core Data Resources: fundamental infrastructure for the life sciences

Drysdale, R.; Cook, C. E.; Petryszak, R.; Baillie Gerritsen, V.; Barlow, M.; Gasteiger, E.; Gruhl, F.; Haas, J.; Lanfear, J.; Lopez, R.; Redaschi, N.; Stockinger, H.; Teixeira, D.; Venkatesan, A.; Core Data Resource Forum, E.; Blomberg, N.; Durinx, C.; McEntyre, J.

10.1101/598318 — bioinformatics — Posted on 2019-04-15

1625 The role of Caulobacter cell surface structures in colonization of the air-liquid interface

Fiebig, A.

10.1101/524058 — microbiology — Posted on 2019-04-14

1626 Comparative transcriptomics analyses across species, organs and developmental stages reveal functionally constrained lncRNAs

Darbellay, F.; Necsulea, A.

10.1101/607200 — evolutionary biology — Posted on 2019-04-14

1627 Dissociating Language and Thought in Human Reasoning

Coetzee, J. P.; Johnson, M. A.; Wu, A. D.; Iacoboni, M.; Monti, M.

10.1101/336123 — neuroscience — Posted on 2019-04-14

1628 Protein features for assembly of the RNA editing helicase 2 subcomplex (REH2C) in Trypanosome holo-editosomes

Kumar, V.; Doharey, P. K.; Gulati, S.; Meehan, J.; Martinez, M. G.; Hughes, K.; Mooers, B. H. M.; Cruz-Reyes, J.

10.1101/524702 — molecular biology — Posted on 2019-04-14

1629 Updated MS2PIP web server delivers fast and accurate MS2 peak intensity prediction for multiple fragmentation methods, instruments and labeling techniques

Gabriels, R.; Martens, L.; Degroeve, S.

10.1101/544965 — bioinformatics — Posted on 2019-04-14

1630 Length regulation of multiple flagella that self-assemble from a shared pool of components

Fai, T. G.; Mohapatra, L.; Kondev, J.; Amir, A.

10.1101/436360 — systems biology — Posted on 2019-04-14

1631 Inferring the function performed by a recurrent neural network

Chalk, M.; Tkacik, G.; Marre, O.

10.1101/598086 — neuroscience — Posted on 2019-04-14

1632 A Chromosome-level Sequence Assembly Reveals the Structure of the Arabidopsis thaliana Nd-1 Genome and its Gene Set

Pucker, B.; Holtgraewe, D.; Stadermann, K. B.; Frey, K.; Huettel, B.; Reinhardt, R.; Weisshaar, B.

10.1101/407627 — genomics — Posted on 2019-04-14

1633 Response to \"No evidence of functional co-adaptation between clustered microRNAs\"

Wang, Y.; Zhang, H.; Lu, J.

10.1101/313817 — evolutionary biology — Posted on 2019-04-14

1634 Theoretical modeling on CRISPR-coded cell lineages: efficient encoding and optimal reconstruction

Sugino, K.; Garcia Marques, J.; Espinosa Medina, I.; Lee, T.

10.1101/538488 — developmental biology — Posted on 2019-04-14

1635 The Anticipation of Events in Time

Grabenhorst, M.; Michalareas, G.; Maloney, L. T.; Poeppel, D.

10.1101/608893 — neuroscience — Posted on 2019-04-14

1636 Reducing false positives in tractography with microstructural and anatomical priors

Schiavi, S.; Barakovic, M.; Ocampo Pineda, M.; Descoteaux, M.; Thiran, J.-P.; Daducci, A.

10.1101/608349 — neuroscience — Posted on 2019-04-14

1637 Genomics, Molecular and Evolutionary Perspective of NAC Transcription Factors

Mohanta, T. K.; Yadav, D.; Khan, A.; Hashem, A.; Tabassum, B.; Khan, A.; Abd_Allah, E. F.; Al-Harrasi, A.

10.1101/608885 — genomics — Posted on 2019-04-14

1638 SaTAnn quantifies translation on the functionally heterogeneous transcriptome

Calviello, L.; Hirsekorn, A.; Ohler, U.

10.1101/608794 — genomics — Posted on 2019-04-14

1639 Translational control of Bcl-2 promotes apoptosis of gastric carcinoma cells

Tao, S.; Gu, J.; Wang, Q.; ZHENG, L.

10.1101/608836 — cancer biology — Posted on 2019-04-14

1640 Interleukin-12 elicits a non-canonical response in B16 melanoma cells to enhance survival

Byrne-Hoffman, C.; Deng, W.; McGrath, O.; Wang, P.; Rojanasakul, Y.; Klinke, D. J.

10.1101/608828 — cancer biology — Posted on 2019-04-14

1641 Resolving single-cell heterogeneity from hundreds of thousands of cells through sequential hybrid clustering and NMF

Venkatasubramanian, M.; Chetal, K.; Atluri, G.; Salomonis, N.

10.1101/608869 — bioinformatics — Posted on 2019-04-14

1642 Host sex and genotype modify the gut microbiome response to helminth infection

Ling, F.; Steinel, N.; Weber, J.; Ma, L.; Smith, C.; Correa, D.; Zhu, B.; Bolnick, D.; Wang, G.

10.1101/608638 — microbiology — Posted on 2019-04-14

1643 VariCarta: a comprehensive database of harmonized genomic variants found in ASD sequencing studies

Belmadani, M.; Jacobson, M.; Holmes, N.; Phan, M.; Pavlidis, P.; Rogic, S.

10.1101/608356 — genomics — Posted on 2019-04-14

1644 Identification of novel key biomarkers in Simpson-Golabi-Behmel Syndrome: Evidence from bioinformatics analysis

Mustafa, M. I.; Abdelmoneim, A. H.; Elfadol, N. M.; Murshed, N. S.; Mohammed, Z. O.; Hassan, M. A.

10.1101/608927 — bioinformatics — Posted on 2019-04-14

1645 In Silico Genetics Revealing Novel Mutations in CEBPA Gene Associated with Acute Myeloid Leukemia

Mustafa, M. I.; Mohammed, Z. O.; Murshed, N. S.; Elfadol, N. M.; Abdelmoneim, A. H.; Hassan, M. A.

10.1101/608943 — bioinformatics — Posted on 2019-04-14

1646 SureTypeSC - A Random Forest and Gaussian Mixture predictor of high confidence genotypes in single cell data

Vogel, I.; Blanshard, R. C.; Hoffmann, E. R.

10.1101/393256 — bioinformatics — Posted on 2019-04-14

1647 Automated segmentation of cortical layers in BigBrain reveals divergent cortical and laminar thickness gradients in sensory and motor cortices.

Wagstyl, K.; Larocque, S.; Cucurull, G.; Lepage, C.; Cohen, J. P.; Bludau, S.; Palomero-Gallagher, N.; Funck, T.; Spitzer, H.; Dicksheid, T.; Fletcher, P. C.; Romero, A.; Zilles, K.; Amunts, K.; Bengio, Y.; Evans, A. C.

10.1101/580597 — neuroscience — Posted on 2019-04-14

1648 Experienced meditators exhibit no differences to demographically-matched controls in theta phase synchronisation, P200, or P300 during an auditory oddball task

Payne, J. R.; Baell, O.; Geddes, H.; Fitzgibbon, B.; Emonson, M.; Hill, A. T.; Van Dam, N. T.; Humble, G.; Fitzgerald, P. B.; Bailey, N. W.

10.1101/608547 — neuroscience — Posted on 2019-04-14

1649 Amygdala controls saccade and gaze physically, motivationally, and socially

Maeda, K.; Inoue, K.-i.; Kunimatsu, J.; Takada, M.; Hikosaka, O.

10.1101/608703 — neuroscience — Posted on 2019-04-14

1650 Ion Condensation onto Ribozyme is Site-Specific and Fold-Dependent

Hori, N.; Denesyuk, N. A.; Thirumalai, D.

10.1101/551994 — biophysics — Posted on 2019-04-13

1651 In situ structure of rotavirus VP1 RNA-dependent RNA polymerase

Jenni, S.; Salgado, E. N.; Herrmann, T.; Li, Z.; Grant, T.; Grigorieff, N.; Trapani, S.; Estrozi, L. F.; Harrison, S. C.

10.1101/605063 — molecular biology — Posted on 2019-04-13

1652 A mixed quantum chemistry/machine learning approach for the fast and accurate prediction of biochemical redox potentials and its large-scale application to 315,000 redox reactions

Jinich, A.; Sanchez-Lengeling, B.; Ren, H.; Harman, R.; Aspuru-Guzik, A.

10.1101/245357 — biophysics — Posted on 2019-04-13

1653 Functional Territories of Human Dentate Nucleus

Guell, X.; D'Mello, A. M.; Hubbard, N. A.; Romeo, R. R.; Gabrieli, J. D.; Whitfield-Gabrieli, S.; Schmahmann, J. D.; Arnold Anteraper, S.

10.1101/608620 — neuroscience — Posted on 2019-04-13

1654 Designer DNA architecture offers precise and multivalent spatial pattern-recognition for viral sensing and inhibition

Kwon, P. S.; Ren, S.; Kwon, S.-J.; Kizer, M. E.; Kuo, L.; Zhou, F.; Zhang, F.; Kim, D.; Fraser, K.; Kramer, L. D.; Seeman, N. C.; Dordick, J. S.; Linhardt, R. J.; Chao, J.; Wang, X.

10.1101/608380 — bioengineering — Posted on 2019-04-13

1655 The Michaelis-Menten paradox: Km is not an equilibrium constant but a steady-state constant.

Canela, E. I.; Navarro, G.; Beltran, J. L.; Franco, R.

10.1101/608232 — biochemistry — Posted on 2019-04-13

1656 A Pandas complex adapted for piRNA-guided transposon silencing

Zhao, K.; Cheng, S.; Miao, N.; Xu, P.; Lu, X.; Wang, M.; Zhang, Y.; Yuan, X.; Liu, W.; Lu, X.; Ouyang, X.; Zhou, P.; Gu, J.; Zhang, Y.; Qiu, D.; Wang, S.; Jin, Z.; Wan, Y.; Ma, J.; Huang, Y.; Yu, Y.

10.1101/608273 — molecular biology — Posted on 2019-04-13

1657 Lytic transglycosylases RlpA and MltC assist in Vibrio cholerae daughter cell separation

Weaver, A. I.; Jimenez-Ruiz, V.; Tallavajhala, S. R.; Ransegnola, B. P.; Wong, K. Q.; Dörr, T.

10.1101/608497 — microbiology — Posted on 2019-04-13

1658 Effect of Electromagnetic Field (EMF) and Electric Field (EF) on Some Behavior of Honeybees (Apis mellifera L.)

Erdogan, Y.; Cengiz, M. M.

10.1101/608182 — animal behavior and cognition — Posted on 2019-04-13

1659 Toward a unified connectomic target for deep brain stimulation in obsessive-compulsive disorder

Li, N.; Baldermann, J. C.; Kibleur, A.; Treu, S.; Elias, G. J. B.; Boutet, A.; Lozano, A. M.; Chabardes, S.; Visser-Vandewalle, V.; Polosan, M.; Kuhn, J.; Kühn, A. A.; Horn, A.

10.1101/608786 — neuroscience — Posted on 2019-04-13

1660 Directional and frequency characteristics of auditory neurons in Culex male mosquitoes

Lapshin, D.; Vorontsov, D.

10.1101/608778 — neuroscience — Posted on 2019-04-13

1661 Mapping-based genome size estimation

Pucker, B.

10.1101/607390 — genomics — Posted on 2019-04-13

1662 CAncer bioMarker Prediction Pipeline (CAMPP) - A standardised and user-friendly framework for the analysis of quantitative biological data.

Terkelsen, T.; Krogh, A.; Papaleo, E.

10.1101/608422 — bioinformatics — Posted on 2019-04-13

1663 Production and use of triploid zebrafish for surrogate reproduction

Franek, R.; Tichopad, T.; Fucikova, M.; Steinbach, C.; Psenicka, M.

10.1101/608687 — zoology — Posted on 2019-04-13

1664 Partial FMRP expression is sufficient to normalize neuronal hyperactivity in Fragile X neurons

Graef, J. D.; Wu, H.; Ng, C.; Sun, C.; Villegas, V.; Qadir, D.; Jesseman, K.; Warren, S.; Jaenisch, R.; Cacace, A.; Wallace, O.

10.1101/608331 — neuroscience — Posted on 2019-04-13

1665 A suite of rare microbes interacts with a dominant, heritable, fungal endophyte to influence plant trait expression

Harrison, J.; Beltran, L. P.; Buerkle, C. A.; Cook, D.; Gardner, D.; Parchman, T. L.; Forister, M. L.

10.1101/608729 — ecology — Posted on 2019-04-13

1666 Spatial clustering of inhibition in mouse primary visual cortex

Bista, P.; D'Souza, R.; Meier, A.; Ji, W.; Burkhalter, A.

10.1101/608125 — neuroscience — Posted on 2019-04-13

1667 Resting-state directed brain connectivity patterns in adolescents from source-reconstructed EEG signals based on information flow rate

Hristopulos, D.; Babul, A.; Babul, S.; Brucar, L. R.; Virji-Babul, N.

10.1101/608299 — neuroscience — Posted on 2019-04-13

1668 A rapid and automated sample-to-result Candida auris real-time PCR assay for high throughput testing of surveillance samples with BD MAX™ open system

Leach, L.; Russell, A.; Chaturvedi, S.; Chaturvedi, V.

10.1101/608190 — microbiology — Posted on 2019-04-13

1669 A shared core microbiome in soda lakes separated by large distances

Zorz, J. K.; Sharp, C. E.; Kleiner, M.; Gordon, P. M.; Pon, R. T.; Dong, X.; Strous, M.

10.1101/608471 — microbiology — Posted on 2019-04-13

1670 Elementary Growth Modes provide a molecular description of cellular self-fabrication

de Groot, D. H.; Hulshof, J.; Teusink, B.; Bruggeman, F.; Planque, R.

10.1101/608083 — systems biology — Posted on 2019-04-13

1671 The disease progression and molecular defense response in Chenopodium quinoa infected with Peronospora variabilis, the causal agent of quinoa downy mildew

Rollano-Penaloza, O. M.; Palma-Encinas, V.; Widell, S.; Rasmusson, A. G.; Mollinedo, P.

10.1101/607465 — plant biology — Posted on 2019-04-13

1672 Individual differences in the influence of mental imagery on conscious perception

Dijkstra, N.; Hinne, M.; Bosch, S. E.; van Gerven, M. A. J.

10.1101/607770 — neuroscience — Posted on 2019-04-13

1673 Whole-genome fingerprint of the DNA methylome during chemically induced differentiation of the human AML cell line HL-60/S4

Antwi, E. B.; Olins, A.; Teif, V. B.; Bieg, M.; Bauer, T.; Gu, Z.; Brors, B.; Eils, R.; Olins, D.; Ishaque, N.

10.1101/608695 — genomics — Posted on 2019-04-13

1674 A generalized framework of AMOVA with any number of hierarchies and any level of ploidies

Huang, K.; Li, Y.; Dunn, D. W.; Zhang, P.; Li, B.

10.1101/608117 — genetics — Posted on 2019-04-13

1675 Variation and selection on codon usage bias across an entire subphylum

LaBella, A. L.; Opulente, D.; Steenwyk, J. L.; Hittinger, C. T.; Rokas, A.

10.1101/608042 — evolutionary biology — Posted on 2019-04-13

1676 Mitochondrial architecture rearrangements produce asymmetrical nonadaptive mutational pressures that subvert the phylogenetic reconstruction in Isopoda

Zhang, D.; Zou, H.; Hua, C.-J.; Li, W.-X.; Mahboob, S.; Al-Ghanim, K. A.; Al-Misned, F.; Jakovlic, I.; Wang, G.-T.

10.1101/607960 — evolutionary biology — Posted on 2019-04-13

1677 An Analytical Theory of Cellular Growth

Dourado, H.; Lercher, M. J.

10.1101/607374 — biophysics — Posted on 2019-04-13

1678 Motto: Representing motifs in consensus sequences with minimum information loss

Wang, M.; Wang, D.; Zhang, K.; Ngo, V.; Fan, S.; Wang, W.

10.1101/607408 — bioinformatics — Posted on 2019-04-13

Lai, L. Y.; Froemer, R.; Festa, E. K.; Heindel, W. C.

10.1101/608240 — neuroscience — Posted on 2019-04-13

1680 The effects of soil phosphorous content on microbiota are driven by the plant phosphate starvation response

Finkel, O. M.; Salas-Gonzalez, I.; Castrillo, G.; Spaepen, S.; Law, T. F.; Jones, C.; Dangl, J. L.

10.1101/608133 — microbiology — Posted on 2019-04-13

1681 Loss-of-function tolerance of enhancers in the human genome

Xu, D.; Gokcumen, O.; Khurana, E.

10.1101/608257 — genomics — Posted on 2019-04-13

1682 Pre-marked chromatin and transcription factor co-binding shape the pioneering activity of Foxa2.

Cernilogar, F. M.; Hasenoeder, S.; Wang, Z.; Scheibner, K.; Burtscher, I.; Sterr, M.; Smialowski, P.; Groh, S.; Evenroed, I. M.; Gilfillan, G. D.; Lickert, H.; Schotta, G.

10.1101/607721 — genomics — Posted on 2019-04-13

1683 Phylogenetic and Spatial Distribution of Evolutionary Isolation and Threat in Turtles and Crocodilians (Non-Avian Archosauromorphs)

Colston, T. J.; Kulkarni, P.; Jetz, W.; Pyron, R. A.

10.1101/607796 — evolutionary biology — Posted on 2019-04-13

1684 VARUS: Sampling Complementary RNA Reads from the Sequence Read Archive

Stanke, M.; Bruhn, W.; Becker, F.; Hoff, K. J.

10.1101/608737 — bioinformatics — Posted on 2019-04-13

1685 Correlation of mRNA delivery timing and protein expression in lipid-based transfection

Reiser, A.; Woschee, D.; Mehrotra, N.; Krzyszton, R.; Strey, H. H.; Raedler, J. O.

10.1101/607986 — systems biology — Posted on 2019-04-13

1686 Efficient enzyme coupling algorithms identify functional pathways in genome-scale metabolic models.

Pradhan, D.; Papin, J. A.; Jensen, P. A.

10.1101/608430 — systems biology — Posted on 2019-04-13

1687 Morpho-anatomical observations on Phyllanthus of Southwestern Bangladesh with two new records for Bangladesh

Tuhin, M. S. H.; Limon, M. S. H.

10.1101/608711 — plant biology — Posted on 2019-04-13

1688 PyRates - A Python Framework for Rate-Based Neural Simulations

Gast, R.; Rose, D. F.; Moeller, H. E.; Weiskopf, N.; Knoesche, T. R.

10.1101/608067 — neuroscience — Posted on 2019-04-13

1689 Biomarker Localization, Analysis, Visualization, Extraction, and Registration (BLAzER) Workflow for Research and Clinical Brain PET Applications

Raman, F.; Grandhi, S.; Murchison, C. F.; Kennedy, R. E.; Landau, S.; Roberson, E. D.; McConathy, J.; Alzheimer's Disease Neuroimaging Initiative,

10.1101/608323 — neuroscience — Posted on 2019-04-13

1690 Experimental manipulation of selfish genetic elements links genes to microbial community function

Quistad, S.; Doulcier, G.; Rainey, P. B.

10.1101/608752 — microbiology — Posted on 2019-04-13

1691 Genomic selection for lentil breeding: empirical evidence

Haile, T. A.; Heidecker, T.; Wright, D.; Neupane, S.; Ramsay, L.; Vandenberg, A.; Bett, K. E.

10.1101/608406 — genomics — Posted on 2019-04-13

1692 Evaluation of the possible association of Body Mass Index and four metabolic gene polymorphisms with longevity in an Italian cohort: a role for APOE, eNOS, and FTO gene polymorphisms.

Santovito, A.; Galli, G.; Ruberto, S.

10.1101/608745 — genetics — Posted on 2019-04-13

1693 Genetic overlap between obsessive-compulsive disorder, related symptoms in the population and insulin signaling: etiological implications

Bralten, J.; Widomska, J.; De Witte, W.; Yu, D.; Mathews, C. A.; Scharf, J. M.; Buitelaar, J.; Crosbie, J.; Schachar, R.; Arnold, P.; Lemire, M.; Burton, C. L.; Franke, B.; Poelmans, G.

10.1101/608034 — genetics — Posted on 2019-04-13

1694 Network science inspires novel tree shape statistics

Chindelevitch, L.; Hayati, M.; Poon, A.; Colijn, C.

10.1101/608646 — bioinformatics — Posted on 2019-04-13

1695 Targeted sequence capture outperforms RNA-Seq and degenerate-primer PCR cloning for sequencing the largest mammalian multi-gene family

Yohe, L. R.; Davies, K. T.; Simmons, N. B.; Sears, K. E.; Dumont, E.; Rossiter, S. J.; Davalos, L.

10.1101/607994 — genomics — Posted on 2019-04-13

1696 Knowledge, attitudes and practices (KAPs) and risk factors of brucellosis at the human-animal interface in the Nile Delta, Egypt

Abd El Wahab, E. W.; Hegazy, Y.; El-Tras, W. F.; Mikeal, A.; kabapy, A. F.; Abdel Fattah, M.; Bruce, M.; ElTholth, M.

10.1101/607655 — epidemiology — Posted on 2019-04-13

1697 Microglia monitor and protect neuronal function via specialized somatic purinergic junctions

Cserep, C.; Posfai, B.; Orsolits, B.; Molnar, G.; Heindl, S.; Lenart, N.; Fekete, R.; Laszlo, Z. I.; Lele, Z.; Schwarcz, A. D.; Ujvari, K.; Csiba, L.; Hortobagyi, T.; Magloczky, Z.; Martinecz, B.; Szabo, G.; Erdelyi, F.; Szipocs, R.; Gesierich, B.; Duering, M.; Katona, I.; Liesz, A.; Tamas, G.; Denes, A.

10.1101/606079 — neuroscience — Posted on 2019-04-13

1698 The Role of the Subthalamic Nucleus in Inhibitory Control of Oculomotor Behavior in Parkinson’s Disease

Bakhtiari, S.; Altinkaya, A.; Pack, C.; Sadikot, A.

10.1101/606897 — neuroscience — Posted on 2019-04-13

1699 Widespread Sexual Dimorphism in the Transcriptome of Human Airway Epithelium in Response to Smoking

Yang, C. X.; Shi, H.; Ding, I.; Yang, C. W. T.; Kim, E. K.-H.; Hackett, T.-L.; Leung, J.; Sin, D. D.; Obeidat, M.

10.1101/602854 — genomics — Posted on 2019-04-13

1700 On the inconsistent treatment of gene-protein-reaction rules in context-specific metabolic models

Ponce de Leon, M.; Apaolaza, I.; Valencia, A.; Planes, F. J.

10.1101/593277 — bioinformatics — Posted on 2019-04-13

1701 Rhythms of Transcription in Field-Grown Sugarcane Are Highly Organ Specific

Dantas, L. L. B.; de Lima, N. O.; Alves-Lima, C.; Nishiyama, M. Y.; Carneiro, M. S.; Souza, G. M.; Hotta, C. T.

10.1101/607002 — plant biology — Posted on 2019-04-13

1702 Antibiotic-induced shifts in fecal microbiota density and composition during hematopoietic stem cell transplantation

Morjaria, S.; Schluter, J.; Taylor, B. P.; Littmann, E. R.; Carter, R. A.; Fontana, E.; Peled, J. U.; van den Brink, M. R. M.; Xavier, J. B.; Taur, Y.

10.1101/606533 — microbiology — Posted on 2019-04-13

1703 Transcriptomic data support a nocturnal bottleneck in the ancestor to gecko lizards

Pinto, B. J.; Nielsen, S. V.; Gamble, T.

10.1101/592873 — evolutionary biology — Posted on 2019-04-13

1704 Muller’s Ratchet and the Long-Term Fate of Chromosomal Inversions

Berdan, E.; Blanckaert, A.; Butlin, R. K.; Bank, C.

10.1101/606012 — evolutionary biology — Posted on 2019-04-13

1705 Imbalance in the response of pre- and post-synaptic components to amyloidopathy

Jackson, J.; Stephen, T.-L.; Tamagnini, F.; Piegsa, J.; Sung, K.; Harvey, J.; Oliver-Evans, A.; Murray, T.; Ahmed, Z.; Hutton, M.; Randall, A.; O'Neill, M.

10.1101/599399 — neuroscience — Posted on 2019-04-13

1706 Diverse phenotypic responses and phosphate content in foxtail millet genotypes under greenhouse and field conditions

Stanislaus, A. C.; Ramakrishnan, M.; Vinod, K. K.; Victor Roch, G.; Upadhyaya, H. D.; Baker, A.; Ignacimuthu, S.

10.1101/607515 — plant biology — Posted on 2019-04-13

1707 U-PASS: unified power analysis and forensics for qualitative traits in genetic association studies

Gao, Z.; Terhorst, J.; Van Hout, C.; Stoev, S.

10.1101/605766 — genetics — Posted on 2019-04-13

1708 Parsers, Data Structures and Algorithms for Macromolecular Analysis Toolkit (MAT): Design and Implementation

Kalyan, G.; Junghare, V.; S, J.; Chattopadhyay, A.; Mitra, P.; Hazra, S.

10.1101/605907 — bioinformatics — Posted on 2019-04-13

1709 A simple model of a quadruped discovers single-foot walking and trotting as energy optimal strategies

Polet, D. T.; Bertram, J. E. A.

10.1101/580779 — zoology — Posted on 2019-04-13

1710 Senescent cells and the dynamics of aging

Karin, O.; Agrawal, A.; Porat, Z.; Krizhanovsky, V.; Alon, U.

10.1101/470500 — systems biology — Posted on 2019-04-13

1711 Molecular framework for TIR1/AFB-Aux/IAA-dependent auxin sensing controlling adventitious rooting in Arabidopsis

Lakehal, A.; Chaabouni, S.; Cavel, E.; Le Hir, R.; Ranjan, A.; Raneshan, Z.; Novak, O.; Pacurar, D. I.; Perrone, I.; Jobert, F.; Gutierrez, L.; Bako, L.; Bellini, C.

10.1101/518357 — plant biology — Posted on 2019-04-13

1712 Neural basis of learning guided by sensory confidence and reward value

Lak, A.; Okun, M.; Moss, M.; Gurnani, H.; Farrell, K.; Wells, M. J.; Reddy, C. B.; Kepecs, A.; Harris, K. D.; Carandini, M.

10.1101/411413 — neuroscience — Posted on 2019-04-13

1713 FasTag: automatic text classification of unstructured medical narratives

Lopez Pineda, A.; Bear Don't Walk, O. J.; Venkataraman, G. R.; Zehnder, A. M.; Ayyar, S.; Page, R. L.; Bustamante, C. D.; Rivas, M. A.

10.1101/429720 — epidemiology — Posted on 2019-04-13

1714 Evolution of neocortical folding: A phylogenetic comparative analysis of MRI from 34 primate species

Heuer, K.; Gulban, O. F.; Bazin, P.-L.; Osoianu, A.; Valabregue, R.; Santin, M.; Herbin, M.; Toro, R.

10.1101/379750 — neuroscience — Posted on 2019-04-13

1715 Tradeoffs and cultural diversity

Karin, O.; Alon, U.

10.1101/263905 — evolutionary biology — Posted on 2019-04-13

1716 Random burst sensing of neurotransmitters

Montague, P. R.; Lohrenz, T.; White, J.; Moran, R. J.; Kishida, K. T.

10.1101/607077 — neuroscience — Posted on 2019-04-13

1717 Yorkie and JNK revert syncytial muscles into myoblasts during Org-1 dependent lineage reprogramming

Schaub, C.; Rose, M.; Frasch, M.

10.1101/607820 — developmental biology — Posted on 2019-04-13

1718 Inflammasome-independent role for NLRP3 in controlling innate anti-helminth immunity and tissue repair in the lung

Chenery, A.; Alhallaf, R.; Agha, Z.; Ajendra, J.; Parkinson, J.; Cooper, M. M.; Chan, B. H.; Eichenberger, R. M.; Dent, L. A.; Robertson, A. A.; Kupz, A.; Brough, D.; Loukas, A.; Sutherland, T. E.; Allen, J. E.; Giacomin, P.

10.1101/606392 — immunology — Posted on 2019-04-13

1719 Aging induces Nlrp3 inflammasome dependent adipose B cell expansion to impair metabolic homeostasis

Camell, C. D.; Lee, A.; Günther, P.; Goldberg, E. L.; Spadaro, O.; Youm, Y.-H.; Bartke, A.; Hubbard, G. B.; Ikeno, Y.; Ruddle, N. H.; Schultz, J. L.; Dixit, V. D.

10.1101/607192 — immunology — Posted on 2019-04-13

1720 Pericytes enable effective angiogenesis in the presence of pro inflammatory signals

Kang, T.-Y.; Bocci, F.; Jolly, M. K.; Levine, H.; Onuchic, J. N.; Levchenko, A.

10.1101/608059 — developmental biology — Posted on 2019-04-13

1721 Inhibiting fibroblast aggregation in skin wounds unlocks developmental pathway to regeneration

Seifert, A. W.; Cook, A. B.; Shaw, D.

10.1101/608075 — developmental biology — Posted on 2019-04-13

1722 Imaging Membrane Curvature inside a Model Immunological Synapse in RBL-2H3 Cells using TIRF Microscopy with Polarized Excitation

Machado, R.; Bendesky, J.; Brown, M.; Spendier, K.; Hagen, G. M.

10.1101/608463 — biophysics — Posted on 2019-04-13

1723 In situ structure of rotavirus VP1 RNA-dependent RNA polymerase

Jenni, S.; Salgado, E. N.; Herrmann, T.; Li, Z.; Grant, T.; Grigorieff, N.; Trapani, S.; Estrozi, L. F.; Harrison, S. C.

10.1101/605063 — molecular biology — Posted on 2019-04-13

1724 Extensive CD8β depletion does not prevent control of viral replication or protection from challenge in macaques chronically infected with a live attenuated simian immunodeficiency virus

Sutton, M. S.; Ellis-Connell, A.; Balgeman, A. J.; Barry, G. L.; Weiler, A. M.; Hetzel, S. J.; Zhou, Y.; Kilby, A.; Mason, R.; Biris, K. K.; Mascola, J. R.; Sullivan, N.; Roederer, M.; Friedrich, T. C.; O'Connor, S. L.

10.1101/608554 — immunology — Posted on 2019-04-13

1725 Lysosomal cystine efflux opposes mTORC1 reactivation through the TCA cycle

Jouandin, P.; Marelja, Z.; Parkhitko, A.; Dambowsky, M.; Asara, J. M.; Nemazanyy, I.; Simons, M.; Perrimon, N.

10.1101/606541 — genetics — Posted on 2019-04-13

1726 Mitofusin 2 regulates neutrophil adhesive migration via suppressing Rac activation

Zhou, W.; Hsu, A. Y.; Wang, T.; Jeffries, J.; Mohammad, H. T.; Wang, X.; Umulis, D. M.; Seleem, M. N.; Deng, Q.

10.1101/608091 — cell biology — Posted on 2019-04-13

1727 Slc7a11 modulated by POU2F1 is involved in pigmentation in rabbit

Chen, Y.; Hu, S.; Mu, L.; Zhao, B.; Wang, M.; Yang, N.; Bao, G.; Zhu, C.; Wu, X.

10.1101/607978 — molecular biology — Posted on 2019-04-13

1728 2’, 3’, 4’-trihydroxychalcone is an Estrogen Receptor Ligand Which Modulates the Activity of 17β-estradiol

Herber, C.; Quirit, J.; Firestone, G.; Krois, C.

10.1101/607275 — molecular biology — Posted on 2019-04-13

1729 Hypotonic stress induces fast, reversible degradation of the vimentin cytoskeleton via intracellular calcium release

Pan, L.; Zhang, P.; Hu, F.; Yan, R.; He, M.; Li, W.; Xu, J.; Xu, K.

10.1101/607416 — cell biology — Posted on 2019-04-13

1730 THE PROTO-ONCOGENE FYN INHIBITS THE ANTI-GLIOBLASTOMA IMMUNE RESPONSE

Comba, A.; Dunn, P. J.; Argento, A. E.; Kadiyala, P.; Ventosa, M.; Zamler, D. B.; Patel, P.; Zhao, L.; Nunez, F. J.; Castro, M. G.; Lowenstein, P. R.

10.1101/608505 — cancer biology — Posted on 2019-04-13

1731 PIP2 Influences the Conformational Dynamics of Membrane bound KRAS4b

McLean, M. A.; Stephen, A. G.; Sligar, S. G.

10.1101/608265 — cancer biology — Posted on 2019-04-13

1732 WRKY1 mediates transcriptional crosstalk between light and nitrogen signaling pathways in Arabidopsis thaliana

Heerah, S.; Katari, M.; Penjor, R.; Coruzzi, G.; Marshall-Colon, A.

10.1101/603142 — plant biology — Posted on 2019-04-13

1733 Integrating regulatory DNA sequence and gene expression to predict genome-wide chromatin accessibility across cellular contexts

Nair, S.; Kim, D. S.; Perricone, J.; Kundaje, A.

10.1101/605717 — genomics — Posted on 2019-04-13

1734 Driving the scalability of DNA-based information storage systems

Tomek, K. J.; Volkel, K.; Simpson, A.; Hass, A. G.; Indermaur, E. W.; Tuck, J.; Keung, A. J.

10.1101/591594 — bioengineering — Posted on 2019-04-13

1735 Atrx deletion in neurons leads to sexually-dimorphic dysregulation of miR-137 and spatial learning and memory deficits

Tamming, R.; Dumeaux, V.; Langlois, L.; Ellegood, J.; Qiu, L. R.; Jiang, Y.; Lerch, J. P.; Berube, N. G.

10.1101/606442 — neuroscience — Posted on 2019-04-13

1736 Chemogenomic profiling of anti-leishmanial efficacy and resistance in the related kinetoplastid parasite Trypanosoma brucei

Collett, C. F.; Kitson, C.; Baker, N.; Steele-Stallard, H. B.; Santrot, M.-V.; Hutchinson, S.; Horn, D.; Alsford, S.

10.1101/605873 — microbiology — Posted on 2019-04-13

1737 A Truly Injectable Neural Stimulation Electrode Made from an In-Body Curing Polymer/Metal Composite

Trevathan, J. K.; Baumgart, I.; Nicolai, E. N.; Gosink, B. A.; Asp, A. J.; Settell, M. L.; Polaconda, S. R.; Malerick, K.; Brodnick, S. K.; Zeng, W.; Knudsen, B. E.; McConico, A. L.; Sanger, Z.; Lee, J. H.; Aho, J. M.; Suminski, A. J.; Ross, E. K.; Lujan, J. L.; Weber, D. J.; Williams, J. C.; Franke, M.; Ludwig, K. A.; Shoffstall, A. J.

10.1101/584995 — bioengineering — Posted on 2019-04-13

1738 Machine learning predicts human prospective decision making

Mei, N.; Olafsson, E.; Rankine, S.; Soto, D.

10.1101/607069 — neuroscience — Posted on 2019-04-13

1739 Predicting the partition of behavioral variability in speed perception with naturalistic stimuli

Chin, B. M.; Burge, J.

10.1101/601161 — neuroscience — Posted on 2019-04-13

1740 Genetic screens identify multiple negative regulators that additively restrict recruitment of the SWI/SNF chromatin remodeler to the HO promoter in Saccharomyces cerevisiae

Parnell, E. J.; Stillman, D. J.

10.1101/606780 — genetics — Posted on 2019-04-13

1741 The representational space of observed actions

Tucciarelli, R.; Wurm, M.; Baccolo, E.; Lingnau, A.

10.1101/592071 — neuroscience — Posted on 2019-04-13

1742 Daedalus and Gasz recruit Armitage to mitochondria, bringing piRNA precursors to the biogenesis machinery

Munafo, M.; Manelli, V.; Falconio, F. A.; Sawle, A.; Kneuss, E.; Eastwood, E. L.; Seah, J. W. E.; Czech, B.; Hannon, G. J.

10.1101/608018 — molecular biology — Posted on 2019-04-13

1743 EMT-induced cell mechanical changes enhance mitotic rounding strength

Hosseini, K.; Taubenberger, A.; Werner, C.; Fischer-Friedrich, E.

10.1101/598052 — biophysics — Posted on 2019-04-13

1744 Molecular framework for TIR1/AFB-Aux/IAA-dependent auxin sensing controlling adventitious rooting in Arabidopsis

Lakehal, A.; Chaabouni, S.; Cavel, E.; Le Hir, R.; Ranjan, A.; Raneshan, Z.; Novak, O.; Pacurar, D. I.; Perrone, I.; Jobert, F.; Gutierrez, L.; Bako, L.; Bellini, C.

10.1101/518357 — plant biology — Posted on 2019-04-13

1745 A novel retroviral vector system to analyze expression from mRNA with retained introns using fluorescent proteins and flow cytometry

Jackson, P. E. H.; Huang, J.; Sharma, M.; Rasmussen, S. K.; Hammarskjold, M.-L.; Rekosh, D.

10.1101/551846 — molecular biology — Posted on 2019-04-13

1746 PyMethylProcess - highly parallelized preprocessing for DNA methylation array data

Levy, J. J.; Titus, A. J.; Salas, L. A.; Christensen, B.

10.1101/604496 — epidemiology — Posted on 2019-04-13

1747 Ultra-compliant carbon nanotube stretchable direct bladder interface

Yan, D.; Bruns, T. M.; Wu, Y.; Zimmerman, L. L.; Stephan, C.; Cameron, A. P.; Yoon, E.; Seymour, J. P.

10.1101/580902 — bioengineering — Posted on 2019-04-13

1748 Surveillance-embedded genomic outbreak resolution of methicillin-susceptible Staphylococcus aureus in a neonatal intensive care unit

Cremers, A. J. H.; Coolen, J.; Bleeker-Rovers, C.; van der Geest-Blankert, N.; Haverkate, D.; Hendriks, H.; Henriet, S.; Huynen, M.; Kolwijck, E.; Liem, D.; Melchers, W.; Rossen, J.; Zoll, J.; van Heijst, A.; Hopman, J.; Wertheim, H.

10.1101/584359 — microbiology — Posted on 2019-04-13

1749 Spatial structure governs the mode of tumour evolution

Noble, R.; Burri, D.; Kather, J. N.; Beerenwinkel, N.

10.1101/586735 — cancer biology — Posted on 2019-04-13

1750 Network remodeling induced by transcranial brain stimulation: A computational model of tDCS-triggered cell assembly formation

Lu, H.; Gallinaro, J. V.; Rotter, S.

10.1101/466136 — neuroscience — Posted on 2019-04-13

1751 Variation in reported human head tissue electrical conductivity values

McCann, H.; Pisano, G.; Beltrachini, L.

10.1101/511006 — neuroscience — Posted on 2019-04-13

1752 A Rap1 binding site and lipid-dependent helix in talin F1 domain promote integrin activation in tandem

Gingras, A.; Lagarrigue, F.; Cuevas, M.; Zorovich, M.; Valadez, A.; Lopez-Ramirez, M. A.; Seban, N.; McLaughlin, W.; Ley, K.; Kiosses, W.; Ginsberg, M.

10.1101/504894 — cell biology — Posted on 2019-04-13

1753 Gene Information eXtension (GIX): effortless retrieval of gene product information on any website

Knight, J. D. R.; Samavarchi-Tehrani, P.; Tyers, M.; Gingras, A.-C.

10.1101/532523 — bioinformatics — Posted on 2019-04-13

1754 Viable and efficient electroporation-based genetic manipulation of unstimulated human T cells

Aksoy, P.; Aksoy, B. A.; Czech, E.; Hammerbacher, J.

10.1101/466243 — immunology — Posted on 2019-04-13

1755 Do Cells use Passwords in Cell-State Transitions? Is Cell Signaling sometimes Encrypted?

Root, A.

10.1101/432120 — systems biology — Posted on 2019-04-13

1756 Category biases in human visual cortex

Ester, E. F.; Sprague, T. C.; Serences, J. T.

10.1101/170845 — neuroscience — Posted on 2019-04-13

1757 Differences in high-definition transcranial direct current stimulation over the motor hotspot versus the premotor cortex on motor network excitability

Lefebvre, S.; Jann, K.; Schmiesing, A.; Ito, K.; Jog, M.; Qiao, Y.; Cabeen, R.; Shi, Y.; Schweighofer, N.; Wang, D. J.; Liew, S.-L.

10.1101/487488 — neuroscience — Posted on 2019-04-13

1758 Evolution of phenotypic plasticity in response to ethanol between sister species with different ecological histories (Drosophila melanogaster and D. simulans)

Signor, S.; Nuzhdin, S.

10.1101/386334 — evolutionary biology — Posted on 2019-04-13

1759 Altered levels of hsromega lncRNAs further enhance Ras signaling during ectopically activated Ras induced R7 differentiation in Drosophila

Ray, M.; Singh, G.; Lakhotia, S. C.

10.1101/224543 — cell biology — Posted on 2019-04-13

1760 Sibe: a computation tool to apply protein sequence statistics to folding and design

Cheung, N. J.; Yu, W.

10.1101/380576 — bioinformatics — Posted on 2019-04-13

1761 A hundred genes implicated in intellectual disability and autism regulate habituation learning and reveal an opposing role for Ras-MAPK signaling in inhibitory and excitatory neurons

Fenckova, M.; Blok, L. E. R.; Asztalos, L.; Cizek, P.; Goodman, D. P.; Singgih, E. L.; Glennon, J. C.; IntHout, J.; Zweier, C.; Eichler, E. E.; von Reyn, C. R.; Bernier, R.; Asztalos, Z.; Schenck, A.

10.1101/285981 — neuroscience — Posted on 2019-04-13

1762 The global diversity of the major parasitic nematode Haemonchus contortus is shaped by human intervention and climate

Salle, G.; Doyle, S. R.; Cortet, J.; Cabaret, J.; Berriman, M.; Holroyd, N.; Cotton, J. A.

10.1101/450692 — genomics — Posted on 2019-04-13

1763 Relocating agriculture could drastically reduce humanity’s ecological footprint

Beyer, R. M.; Manica, A.; Rademacher, T. T.

10.1101/488841 — ecology — Posted on 2019-04-13

1764 Identification of Kinase Inhibitors that Regulate Nuclear Receptor Nurr1 (NR4A2) Cellular Activity

Williams, K. L.; Wells, C. I.; Moore, J. T.

10.1101/420976 — pharmacology and toxicology — Posted on 2019-04-13

1765 Pharmacologic activation of G protein-coupled estrogen receptor inhibits pancreatic ductal adenocarcinoma

Natale, C. A.; Li, J.; Dentchev, T.; Capell, B.; Seykora, J.; Stanger, B.; Ridky, T.

10.1101/365668 — cancer biology — Posted on 2019-04-13

1766 Modeling stimulus-dependent variability improves decoding of population neural responses

Ghanbari, A.; Christopher, L. M.; Read, H. L.; Stevenson, I.

10.1101/146415 — neuroscience — Posted on 2019-04-13

1767 Profiling Myelodysplastic Syndromes by Mass Cytometry Demonstrates Abnormal Progenitor Cell Phenotype and Differentiation

Behbehani, G. K.; Finck, R.; Samusik, N.; Sridhar, K. J.; Fantl, W. J.; Greenberg, P. L.; Nolan, G. P.

10.1101/604397 — cancer biology — Posted on 2019-04-12

1768 Gibbs Process Determines Survival and Reveals Contact-Inhibition Genes in Glioblastoma Multiforme

Kannan, L.; Agarwal, T.; Fenyo, D.; Tsirigos, A.; Snuderl, M.; Zagzag, D.; Sulman, E.; Huse, J.; Kannan, K.

10.1101/608414 — cancer biology — Posted on 2019-04-12

1769 Association between body mass index (BMI) and hypertension in South Asian population: Evidence from Demographic and Health Survey

Hossain, F. B.; Shawon, M. S. R.; Adhikary, G.; Chowdhury, A.

10.1101/605469 — epidemiology — Posted on 2019-04-12

1770 PyMethylProcess - highly parallelized preprocessing for DNA methylation array data

Levy, J. J.; Titus, A. J.; Salas, L. A.; Christensen, B.

10.1101/604496 — epidemiology — Posted on 2019-04-12

1771 Potential impacts on animal health and welfare of raising animals without antibiotics

Singer, R. S.; Porter, L. J.; Thomson, D. U.; Gage, M.; Beaudoin, A.; Wishnie, J. K.

10.1101/600965 — epidemiology — Posted on 2019-04-12

1772 Gene-methylation interactions: Discovering region-wise DNA methylation levels that modify SNP-associated disease risk

Romanowska, J.; Haaland, O. A.; Jugessur, A.; Gjerdevik, M.; Xu, Z.; Taylor, J.; Wilcox, A. J.; Jonassen, I.; Lie, R. T.; Gjessing, H. K.

10.1101/593053 — epidemiology — Posted on 2019-04-12

1773 A data-driven, meaningful, easy to interpret, population-independent accelerometer outcome variable for global surveillance

Rowlands, A. V.; Sherar, L.; Fairclough, S. J.; Yates, T.; Edwardson, C. L.; Harrington, D. M.; Davies, M.; Munir, F.; Khunti, K.; Stiles, V. H.

10.1101/604694 — epidemiology — Posted on 2019-04-12

1774 A polygenic risk score for breast cancer in U.S. Latinas and Latin-American women

Shieh, Y.; Fejerman, L.; Lott, P. C.; Marker, K.; Sawyer, S. D.; Hu, D.; Huntsman, S.; Torres, J.; Echeverry, M.; Bohorquez, M. E.; Martinez-Chequer, J. C.; Polanco-Echeverry, G.; Estrada-Florez, A. P.; Haiman, C. A.; John, E. M.; Kushi, L. H.; Torres-Mejia, G.; Viadaurre, T.; Weitzel, J. N.; Casavilco Zambrano, S.; Carvajal-Carmona, L. G.; Ziv, E.; Neuhausen, S. L.

10.1101/598730 — epidemiology — Posted on 2019-04-12

1775 Optimal dynamic empirical therapy in a health care facility: an artificial intelligence approach

Houy, N.; Flaig, J.

10.1101/603464 — epidemiology — Posted on 2019-04-12

1776 Commercial gene expression tests for prostate cancer prognosis provide paradoxical estimates of race-specific risk

Creed, J. H.; Berglund, A. E.; Rounbehler, R. J.; Awasthi, S.; Cleveland, J. L.; Park, J. Y.; Yamoah, K.; Gerke, T. A.

10.1101/604058 — epidemiology — Posted on 2019-04-12

1777 Early transmission of Plasmodium vivax sensitive strain slows down emergence of drug resistance

Canon, M.; Villela, D.

10.1101/603597 — epidemiology — Posted on 2019-04-12

1778 Deep Learning of Markov Model Based Machines for Determination of Better Treatment Option Decisions for Infertile Women

Rao, A.; Diamond, M.

10.1101/606921 — epidemiology — Posted on 2019-04-12

1779 Sentinel Case of Candida auris in the Western United States Following Prolonged Occult Colonization in a Returned Traveler from India

Woodworth, M. H.; Dynerman, D.; Crawford, E. D.; Li, L. M.; Doernberg, S. B.; Ramirez, L.; Serpa, P. H.; Nichols, A.; Lyden, A.; Tato, C. M.; Miller, S.; Derisi, J. L.; Langelier, C.

10.1101/601559 — epidemiology — Posted on 2019-04-12

1780 Prevalence of Refractive Error and Need for Corrective Lenses in Medically Underserved Residents of Tijuana, Mexico

Ubels, J. L.; Ismond, J. M.; Timmermans, M. A.; Hoogewerf, A. J.

10.1101/602805 — epidemiology — Posted on 2019-04-12

1781 Proxy gene-by-environment Mendelian randomization study confirms a causal effect of maternal smoking on offspring birthweight, but little evidence of long-term influences on offspring health

Yang, Q.; Millard, L. A. C.; Davey Smith, G.

10.1101/601443 — epidemiology — Posted on 2019-04-12

1782 Double burden of malnutrition in children aged 24-59 months by socioeconomic status in five South Asian countries: evidence from Demographic and Health Surveys

Hossain, F. B.; Shawon, M. S. R.; Al-Abid, M. S. U.; Sami, S. M.; Adhikary, G.; Bulbul, M. M. I.

10.1101/605402 — epidemiology — Posted on 2019-04-12

1783 Socio-behavioural characteristics and HIV: findings from a causal modelling analysis of 29 sub-Saharan African countries

Baranczuk, Z.; Estill, J.; Blough, S.; Meier, S.; Merzouki, A.; Maathuis, M. H.; Keiser, O.

10.1101/600510 — epidemiology — Posted on 2019-04-12

1784 Toxoplasma gondii in house mice Mus musculus domesticus from Dakar, Senegal: clues for oral rather than vertical mode of infection

Galal, L.; Stragier, C.; Boumediene, F.; Hamidovic, A.; Maugrion, O.; Darde, M.-L.; Brouat, C.; Mercier, A.

10.1101/605014 — epidemiology — Posted on 2019-04-12

1785 The Dialysis Procedure Triggers Autonomic Imbalance and Cardiac Arrhythmias: Insights from Continuous 14-day ECG Monitoring

Rogovoy, N. M.; Howell, S. J.; Lee, T. L.; Hamilton, C.; Perez-Alday, E. A.; Kabir, M. M.; Li-Pershing, Y.; Zhang, Y.; Kim, E. D.; Fitzpatrick, J.; Monroy-Trujillo, J. M.; Estrella, M. M.; Sozio, S. M.; Jaar, B. G.; Parekh, R. S.; Tereshchenko, L. G.

10.1101/601542 — epidemiology — Posted on 2019-04-12

1786 Arbovirus emergence in temperate climates: the case of Cordoba, Argentina, 2009-2018

Robert, M. A.; Tinunin, D. T.; Benitez, E. M.; Ludena-Almeida, F.; Romero, M.; Stewart Ibarra, A. M.; Estallo, E. L.

10.1101/602003 — epidemiology — Posted on 2019-04-12

1787 Using the basic reproduction number to assess the risk of transmission of lumpy skin disease virus by biting insects

Gubbins, S.

10.1101/602292 — epidemiology — Posted on 2019-04-12

1788 How delayed treatment benefits and harms would impact the optimal timing of statin initiation for cardiovascular primary prevention

Hayward, R. A.; Schell, G.; Robinson, J. G.; Sussman, J.; Lavieri, M.

10.1101/608216 — epidemiology — Posted on 2019-04-12

1789 Transpositional scaling and niche transitions restore organ size and shape during zebrafish fin regeneration

Stewart, S.; Yette, G. A.; Henner, A. L.; Le Bleu, H. K.; Braunstein, J. A.; Chehab, J. W.; Harms, M. J.; Stankunas, K.

10.1101/606970 — developmental biology — Posted on 2019-04-12

1790 An electrophysiological approach to measure changes in the membrane surface potential in real time

Sandtner, W.; Burtscher, V.; Hotka, M.; Freissmuth, M.

10.1101/607945 — biophysics — Posted on 2019-04-12

1791 Coupled inter-subunit dynamics enable the fastest CO2-fixation by reductive carboxylases

Demirci, H.; Rao, Y.; Stoffel, G. M.; Vögeli, B.; Schell, K.; Batyuk, A.; Gati, C.; Sierra, R. G.; Hunter, M. S.; Dao, E. H.; Ciftci, H. I.; Hayes, B.; Poitevin, F.; Tono, K.; Adrian Saez, D.; Vöhringer-Martinez, E.; Deutsch, S.; Yoshikuni, Y.; Erb, T. J.; Wakatsuki, S.

10.1101/607101 — biophysics — Posted on 2019-04-12

1792 MerMAIDs: A novel family of metagenomically discovered, marine, anion-conducting and intensely desensitizing channelrhodopsins.

Oppermann, J.; Fischer, P.; Silapetere, A.; Liepe, B.; Rodriguez-Rozada, S.; Flores-Uribe, J.; Peter, E.; Keidel, A.; Vierock, J.; Kaufmann, J.; Broser, M.; Luck, M.; Bartl, F.; Hildebrandt, P.; Wiegert, J. S.; Beja, O.; Hegemann, P.; Wietek, J.

10.1101/607804 — biophysics — Posted on 2019-04-12

1793 Mesoscale Modeling of a Nucleosome-Binding Antibody (PL2-6): Mono- vs. Bivalent Chromatin Complexes

Myers, C. G.; Olins, D. E.; Olins, A. L.; Schlick, T.

10.1101/607218 — biophysics — Posted on 2019-04-12

1794 Flotillin-dependent lipid-raft microdomains are required for functional phagolysosomes against fungal infections

Schmidt, F.; Thywissen, A.; Röcker, M.; Cunha, C.; Cseresnyes, Z.; Schmidt, H.; Galiani, S.; Gräler, M. H.; Chamilos, G.; Lacerda, J. F.; Campos, A.; Eggeling, C.; Figge, T.; Heinekamp, T.; Filler, S. G.; Carvalho, A.; Brakhage, A. A.

10.1101/606939 — microbiology — Posted on 2019-04-12

1795 Membrane dynamics of Notch-bound γ-secretase produces two distinct Notch conformations

Tang, N.; Dehury, B.; Kepp, K. P.

10.1101/607846 — biophysics — Posted on 2019-04-12

1796 Crippling the bacterial cell wall molecular machinery

Williams, A. H.; Boneca, I.; Wheeler, R.; Deghmane, A.-E.; Santecchia, I.; Impens, F.; Bastos, P. A. D.; Hicham, S.; Moya Nilges, M.; Malosse, C.; Chamot-Rooke, J.; Haouz, A.; Robins, W. P.; Taha, M.-K.

10.1101/607697 — biochemistry — Posted on 2019-04-12

1797 Targeted DNA transposition using a dCas9-transposase fusion protein

Bhatt, S.; Chalmers, R.

10.1101/571653 — biochemistry — Posted on 2019-04-12

1798 Human extinction learning is accelerated by an angiotensin antagonist via ventromedial prefrontal cortex and its connections with basolateral amygdala

Zhou, F.; Geng, Y.; Xin, F.; Li, J.; Feng, P.; Liu, C.; Zhao, W.; Feng, T.; Guastella, A.; Ebstein, R.; Kendrick, K.; Becker, B.

10.1101/512657 — clinical trials — Posted on 2019-04-12

1799 Sound comparison of seven TMS coils at matched simulation strength

Koponen, L. M.; Goetz, S. M.; Peterchev, A. V.

10.1101/606418 — neuroscience — Posted on 2019-04-12

1800 Escherichia coli’s physiology can turn membrane voltage dyes into actuators

Mancini, L.; Terradot, G.; Tian, T.; Pu, Y.; Li, Y.; Lo, C.-J.; Bai, F.; Pilizota, T.

10.1101/607838 — biophysics — Posted on 2019-04-12

1801 Impaired KCC2 phosphorylation leads to neuronal network dysfunction and neurodevelopmental pathogenesis.

Pisella, L.; Gaiarsa, J.-L.; Diabira, D.; Zhang, J.; Khalilov, I.; Duan, J.; Kahle, K.; Medyna, I.

10.1101/606566 — neuroscience — Posted on 2019-04-12

1802 A model of the entrance pupil of the human eye

Aguirre, G. K.

10.1101/325548 — neuroscience — Posted on 2019-04-12

1803 Iba1+ Microglia Colocalize with Synaptophysin+ and Homer1+ Puncta and Reveal Two Novel Sub-types of GABAergic Neuron in Guinea Pig Inferior Colliculus

Webb, S. D.; Orton, L. D.

10.1101/606509 — neuroscience — Posted on 2019-04-12

1804 Impact of NaCl, nitrate and temperature on the microbial community of a methanol-fed, denitrifying marine biofilm

Villemur, R.; Payette, G.; Geoffroy, V.; Mauffrey, F.; Martineau, C.

10.1101/607028 — microbiology — Posted on 2019-04-12

1805 Posttranscriptional regulation of ribosomal and multiresistance genes by the bacterial leader peptide peTrpL

Melior, H.; Li, S.; Stoetzel, M.; Foerstner, K. U.; Maass, S.; Schuetz, R.; Azarderakhsh, S.; Barth-Weber, S.; Shevkoplias, A.; Baumgardt, K.; Chervontseva, Z.; Ziebuhr, J.; Ahrens, C.; Evguenieva-Hackenberg, E.

10.1101/606483 — microbiology — Posted on 2019-04-12

1806 Immuno-genomic Pan-cancer Landscape Reveals Diverse Immune Escape Mechanisms and Immuno-Editing Histories

Mizuno, S.; Yamaguchi, R.; Hasegawa, T.; Hayashi, S.; Fujita, M.; Zhang, F.; Koh, Y.; Lee, S.-Y.; Yoon, S.-S.; Shimizu, E.; Komura, M.; Fujimoto, A.; Nagai, M.; Kato, M.; Liang, H.; Miyano, S.; Zhang, Z.; Nakagawa, H.; Imoto, S.

10.1101/285338 — genomics — Posted on 2019-04-12

1807 Reliable Phylogenetic Regressions for Multivariate Comparative Data: Illustration with the MANOVA and Application to the Effect of Diet on Mandible Morphology in Phyllostomid Bats

Clavel, J.; Morlon, H.

10.1101/606491 — evolutionary biology — Posted on 2019-04-12

1808 Spontaneous isomerization of long-lived proteins provides a molecular mechanism for the lysosomal failure observed in Alzheimer’s disease

Lambeth, T.; Riggs, D.; Talbert, L.; Tang, J.; Coburn, E.; Kang, A.; Noll, J.; Augello, C.; Ford, B.; Julian, R.

10.1101/605626 — biochemistry — Posted on 2019-04-12

1809 Proposing the solar wind-energy-flux hypothesis as a driver of interannual variation in tropical tree reproductive effort

Hogan, J. A.; Nytch, C. J.; Bithorn, J. E.; Zimmerman, J. K.

10.1101/606871 — plant biology — Posted on 2019-04-12

1810 UNI-EM: An Environment for Deep Neural Network-Based Automated Segmentation of Neuronal Electron Microscopic Images

Urakubo, H.; Bullmann, T.; Kubota, Y.; Oba, S.; Ishii, S.

10.1101/607366 — neuroscience — Posted on 2019-04-12

1811 Global analyses of the dynamics of mammalian microRNA metabolism

Kingston, E.; Bartel, D.

10.1101/607150 — molecular biology — Posted on 2019-04-12

1812 The Virulence Index: A Metric for Quantitative Analysis of Phage Virulence

Storms, Z. J.; Teel, M. R.; Mercurio, K.; Sauvageau, D.

10.1101/606350 — microbiology — Posted on 2019-04-12

1813 Indomethacin-induced gut damage in a surrogate insect model, Galleria mellonella

Emery, H.; Johnston, R.; Rowley, A. F.; Coates, C. J.

10.1101/606319 — immunology — Posted on 2019-04-12

1814 Mitotic exit is controlled during anaphase by an Aurora B-Cyclin B1/Cdk1 crosstalk

Maiato, H.; Afonso, O.; Cheeseman, L.; Ferreira, L.; Morais-de-Sa, E.

10.1101/606517 — cell biology — Posted on 2019-04-12

1815 Acquired FGFR and FGF alterations confer resistance to estrogen receptor (ER) targeted therapy in ER+ metastatic breast cancer

Mao, P.; Cohen, O.; Kowalski, K. J.; Kusiel, J. G.; Buendia-Buendia, J. E.; Exman, P.; Wander, S. A.; Waks, A. G.; Chung, J.; Miller, V. A.; Federica Piccioni, F.; Root, D. E.; Winer, E. P.; Lin, N. U.; Wagle, N.

10.1101/605436 — cancer biology — Posted on 2019-04-12

1816 Proteases as Biological Bits for Programmable Medicine

Holt, B.; Kwong, G. A.

10.1101/607895 — bioengineering — Posted on 2019-04-12

1817 Rescuing the attentional performance of rats with cholinergic losses by the M1 positive allosteric modulator TAK-071

Kucinski, A.; Phillips, K.; Koshy Cherian, A.; Sarter, M.

10.1101/606343 — neuroscience — Posted on 2019-04-12

1818 Atrx deletion in neurons leads to sexually-dimorphic dysregulation of miR-137 and spatial learning and memory deficits

Tamming, R.; Dumeaux, V.; Langlois, L.; Ellegood, J.; Qiu, L. R.; Jiang, Y.; Lerch, J. P.; Berube, N. G.

10.1101/606442 — neuroscience — Posted on 2019-04-12

1819 More than efficacy revealed by single-cell analysis of antiviral therapeutics

Liu, W.; Caglar, M.; Mao, Z.; Woodman, A.; Arnold, J.; Wilke, C.; Cameron, C. E.

10.1101/606715 — microbiology — Posted on 2019-04-12

1820 Metabolic and metagenomic profiling of hydrocarbon-degrading microorganisms obtained from the deep biosphere of the Gulf of Mexico

Moreno Ulloa, A.; Sicairos Diaz, V.; Tejeda Mora, J. A.; Macias Contreras, M. I.; Diaz Castillo, F.; Guerrero, A.; Gonzales Sanchez, R.; Vazquez Duhalt, R.; Licea Navarro, A.

10.1101/606806 — microbiology — Posted on 2019-04-12

1821 STAT5: A Target of Antagonism by Neurotropic Flaviviruses

Zimmerman, M. G.; Bowen, J. R.; McDonald, C. E.; Young, E.; Baric, R. S.; Pulendran, B.; Suthar, M. S.

10.1101/606608 — microbiology — Posted on 2019-04-12

1822 Origin of elevational replacements in a clade of nearly flightless birds - most diversity in tropical mountains accumulates via secondary contact following allopatric speciation

Cadena, D.; Cespedes, L. N.

10.1101/606558 — evolutionary biology — Posted on 2019-04-12

1823 Heat-triggered remote control of CRISPR-dCas9 for tunable transcriptional modulation

Gamboa, L.; Phung, E. V.; Li, H.; Meyers, J. P.; Kwong, G.

10.1101/606723 — bioengineering — Posted on 2019-04-12

1824 Evaluation of parameters affecting performance and reliability of machine learning-based antibiotic susceptibility testing from whole genome sequencing data

Hicks, A. L.; Wheeler, N.; Sanchez-Buso, L.; Rakeman, J. L.; Harris, S. R.; Grad, Y. H.

10.1101/607127 — microbiology — Posted on 2019-04-12

1825 Endothelial sphingosine 1-phosphate receptors promote vascular normalization to influence tumor growth and metastasis

Cartier, A.; Leigh, T.; Liu, C. H.; Hla, T.

10.1101/606434 — cancer biology — Posted on 2019-04-12

1826 Spatiotemporal organization of branched microtubule networks

Thawani, A.; Stone, H. A.; Shaevitz, J. W.; Petry, S.

10.1101/606889 — biophysics — Posted on 2019-04-12

1827 Molecular Transport across Lipid Membranes Controls Cell-Free Expression Level and Dynamics

Caveney, P. M.; Dabbs, R. M.; McClintic, W. T.; Collier, C. P.; Simpson, M. L.

10.1101/606863 — biophysics — Posted on 2019-04-12

1828 MCHM acts as a hydrotrope, altering the balance of metals in yeast

Pupo, A.; Ayers, M. C.; Sherman, Z. N.; Vance, R. J.; Cumming, J. R.; Gallagher, J. E. G.

10.1101/606426 — biochemistry — Posted on 2019-04-12

1829 Machine learning predicts human prospective decision making

Mei, N.; Olafsson, E.; Rankine, S.; Soto, D.

10.1101/607069 — neuroscience — Posted on 2019-04-12

1830 MiR-219 deficiency in Alzheimer’s disease contributes to neurodegeneration and memory dysfunction through post-transcriptional regulation of tau-kinase network

Arnes, M.; Kim, Y. A.; Lannes, J.; Alaniz, M. E.; Cho, J. D.; McCabe, B. D.; Santa-Maria, I.

10.1101/607176 — neuroscience — Posted on 2019-04-12

1831 Dissecting the transcriptomic basis of phenotypic evolution in an aquatic keystone grazer

Frisch, D.; Becker, D.; Wojewodzic, M. W.

10.1101/606988 — evolutionary biology — Posted on 2019-04-12

1832 A Single Defined Sister Chromatid Fusion Destabilizes Cell Cycle through Micronuclei Formation

Kagaya, K.; Noma, N.; Yamamoto, I.; Tashiro, S.; Ishikawa, F.; Hayashi, M. T.

10.1101/607341 — cell biology — Posted on 2019-04-12

1833 3D Multicolor Nanoscopy at 10,000 Cells a Day

Barentine, A. E. S.; Lin, Y.; Liu, M.; Kidd, P.; Balduf, L.; Grace, M. R.; Wang, S.; Bewersdorf, J.; Baddeley, D.

10.1101/606954 — biophysics — Posted on 2019-04-12

1834 DeeplyEssential: A Deep Neural Network for Predicting Essential Genes in Microbes

Hasan, M. A.; Lonardi, S.

10.1101/607085 — bioinformatics — Posted on 2019-04-12

1835 Stochastic Lanczos estimation of genomic variance components for linear mixed-effects models

Border, R.; Becker, S.

10.1101/607168 — bioinformatics — Posted on 2019-04-12

1836 Mutational Analysis of an Intrinsically Disordered Region in the E. coli Phosphatase CheZ, a Regulator of Chemotaxis

Ward, A.; Kamegne, M.; Dillard, P.; Moore, J. T.

10.1101/607010 — biochemistry — Posted on 2019-04-12

1837 Chromatin-sensitive cryptic promoters putatively encode alternative protein isoforms in yeast.

Wei, W.; Hennig, B.; Wang, J.; Zhang, Y.; Pareja Sanchez, Y.; Chabbert, C. D.; Adjalley, S. H.; Steinmetz, L. M.; Pelechano, V.

10.1101/403543 — genomics — Posted on 2019-04-12

1838 Bacterial defiance as a form of prodrug failure

Holt, B. A.; Curro, I.; Kwong, G. A.

10.1101/556951 — bioengineering — Posted on 2019-04-12

1839 Experimentally-induced and real-world acute anxiety have no effect on goal-directed behaviour.

Gillan, C. M.; Vaghi, M. M.; Hezemans, F. H.; van Ghesel Grothe, S.; Dafflon, J.; Bruhl, A. B.; Savulich, G.; Robbins, T. W.

10.1101/606145 — animal behavior and cognition — Posted on 2019-04-12

1840 Machine learning prediction of emesis and gastrointestinal state in ferrets

Nanivadekar, A. C.; Miller, D. M.; Fulton, S.; Wong, L.; Ogren, J.; Chitnis, G.; McLaughlin, B.; Zhai, S.; Fisher, L. E.; Yates, B. J.; Horn, C. C.

10.1101/607242 — neuroscience — Posted on 2019-04-12

1841 Structure and autoregulation of a P4-ATPase lipid flippase

Timcenko, M.; Lyons, J. A.; Januliene, D.; Ulstrup, J.; Dieudonne, T.; Montigny, C.; Ash, M. R.; Karlsen, J. L.; Boesen, T.; Kühlbrandt, W.; Lenoir, G.; Moeller, A.; Nissen, P.

10.1101/606061 — molecular biology — Posted on 2019-04-12

1842 Derivation of Poly-Methylomic Profile Scores for Schizophrenia

Watkeys, O. J.; Cohen-Woods, S.; Quide, Y.; Cairns, M.; Overs, B.; Fullerton, J.; Green, M. J.

10.1101/607309 — genetics — Posted on 2019-04-12

1843 Halyos: A patient-facing visual EHR interface for longitudinal risk awareness

Mataraso, S.; Socrates, V.; Lekschas, F.; Gehlenborg, N.

10.1101/597583 — bioinformatics — Posted on 2019-04-12

1844 Exploring dimension-reduced embeddings with Sleepwalk

Ovchinnikova, S.; Anders, S.

10.1101/603589 — bioinformatics — Posted on 2019-04-12

1845 Alarm tones, music and their elements: A mixed methods analysis of reported waking sounds for the prevention of sleep inertia.

McFarlane, S. J.; Garcia, J. E.; Verhagen, D. S.; Dyer, A. G.

10.1101/607358 — animal behavior and cognition — Posted on 2019-04-12

1846 Xyloglucan homeostasis and microtubule dynamics synergistically maintain meristem geometry and robustness of phyllotaxis in Arabidopsis

Zhao, F.; CHEN, W.; Sechet, J.; Martin, M.; Bovio, S.; Lionnet, C.; Long, Y.; Battu, V.; Mouille, G.; Moneger, F.; Traas, J.

10.1101/607481 — plant biology — Posted on 2019-04-12

1847 TMS of V1 eliminates unconscious processing of chromatic stimuli

Hurme, M.; Koivisto, M.; Henriksson, L.; Railo, H.

10.1101/606095 — neuroscience — Posted on 2019-04-12

1848 Brain age prediction reveals aberrant brain white matter in schizophrenia and bipolar disorder: A multi-sample diffusion tensor imaging study

Toennesen, S.; Kaufmann, T.; Richard, G.; Doan, N. T.; Alnaes, D.; van der Meer, D.; Rokicki, J.; Moberget, T.; Maximov, I. I.; Agartz, I.; Aminoff, S. R.; Barch, D.; Beresniewicz, J.; Cervenka, S.; Craven, A.; Flyckt, L.; Gurholt, T. P.; Haukvik, U. K.; Hugdahl, K.; Johnsen, E.; Jonsson, E. G.; Kolskaar, K. K.; Kompus, K.; Kroken, R. A.; Lagerberg, T. V.; Loeberg, E.-M.; Nordvik, J. E.; Sanders, A.-M.; Ulrichsen, K. M.; Andreassen, O. A.; Westlye, L. T.

10.1101/607754 — neuroscience — Posted on 2019-04-12

1849 Comparing open-source toolboxes for processing and analysis of spike and local field potentials data

Unakafova, V. A.; Gail, A.

10.1101/600486 — neuroscience — Posted on 2019-04-12

1850 Nuclear RNA export factor variant initiates piRNA-guided co-transcriptional silencing

Murano, K.; Iwasaki, Y. W.; Ishizu, H.; Mashiko, A.; Shibuya, A.; Kondo, S.; Adachi, S.; Suzuki, S.; Saito, K.; Natsume, T.; Siomi, M. C.; Siomi, H.

10.1101/605725 — molecular biology — Posted on 2019-04-12

1851 Investigation on the effect of sonic stimulation on Xanthomonas campestris at the whole transcriptome level

Patel, P.; Joshi, C.; Kothari, V.

10.1101/607663 — microbiology — Posted on 2019-04-12

1852 The neglected part of the microbiome: Prophage TJ1 regulates the bacterial community of the metaorganism Hydra

Lange, J.; Fraune, S.; Bosch, T. C.; Lachnit, T.

10.1101/607325 — microbiology — Posted on 2019-04-12

1853 Rapid discovery of synthetic DNA sequences to rewrite endogenous T cell circuits

Roth, T. L.; Li, P. J.; Nies, J.; Yu, R.; Nguyen, M. L. T.; Lee, Y.; Apathy, R.; Truong, A.; Hiatt, J.; Wu, D.; Nguyen, D. N.; Goodman, D.; Bluestone, J. A.; Roybal, K.; Shifrut, E.; Marson, A.

10.1101/604561 — immunology — Posted on 2019-04-12

1854 Investigation of the pathogenic RFC1 repeat expansion in a Canadian and a Brazilian ataxia cohort: identification of novel conformations

Akcimen, F.; Ross, J. P.; Bourassa, C. V.; Liao, C.; Rochefort, D.; Gama, M. T. D.; Dicarie, M.-J.; Barsottini, O. G. P.; Brais, B.; Pedroso, J. L.; Dion, P. A.; Rouleau, G. A.

10.1101/593871 — genetics — Posted on 2019-04-12

1855 Environment Shapes the Accessible Daptomycin Resistance Mechanisms in Enterococcus faecium

Prater, A. G.; Mehta, H. H.; Kosgei, A. J.; Miller, W. R.; Tran, T. T.; Arias, C. A.; Shamoo, Y.

10.1101/607440 — evolutionary biology — Posted on 2019-04-12

1856 Comparative transcriptomics analyses across species, organs and developmental stages reveal functionally constrained lncRNAs

Darbellay, F.; Necsulea, A.

10.1101/607200 — evolutionary biology — Posted on 2019-04-12

1857 piNET: a versatile web platform for downstream analysis and visualization of proteomics data

Shamsaei, B.; Chojnacki, S.; Pilarczyk, M.; Najafabadi, M.; Chen, C.; Ross, K.; Matlock, A.; Muhlich, J.; Chutipongtanate, S.; Vidovic, D.; Sharma, V.; Vasiliauskas, J.; Jaffe, J.; MacCoss, M.; Wu, C.; Pillai, A.; Maayan, A.; Schurer, S.; Medvedovic, M.; Meller, J.

10.1101/607432 — bioinformatics — Posted on 2019-04-12

1858 Assessing the viability of biochemical networks across planets

Smith, H. B.; Drew, A.; Walker, S. I.

10.1101/607531 — systems biology — Posted on 2019-04-12

1859 Diverse phenotypic responses and phosphate content in foxtail millet genotypes under greenhouse and field conditions

Stanislaus, A. C.; Ramakrishnan, M.; Vinod, K. K.; Victor Roch, G.; Upadhyaya, H. D.; Baker, A.; Ignacimuthu, S.

10.1101/607515 — plant biology — Posted on 2019-04-12

1860 Molecular changes in Mesembryanthemum crystallinum guard cells underlying the C3 to CAM transition

Kong, W.; Yoo, M.-j.; Noble, J. D.; Kelley, T. M.; Li, J.; Kirst, M.; Assmann, S. M.; Chen, S.

10.1101/607333 — plant biology — Posted on 2019-04-12

1861 Redox potential defines functional states of adult hippocampal stem cells

Adusumilli, V. S.; Kempermann, ; Walker, T. L.; Overall, R. W.; Klatt, G. M.; Zocher, S.; Zeidan, S. A.; Fischer, T. J.; Sykes, A. M.; Reinhardt, S.; Dahl, A.; Kirova, D. G.; Mansfeld, J.; Runker, A. E.

10.1101/606186 — neuroscience — Posted on 2019-04-12

1862 Interspecies signaling generates exploratory motility in Pseudomonas aeruginosa

Limoli, D. H.; Donegan, N. P.; Warren, E. A.; Cheung, A. L.; O'Toole, G.

10.1101/607523 — microbiology — Posted on 2019-04-12

1863 Genomic prediction accuracies and abilities for growth and wood quality traits of Scots pine, using genotyping-by-sequencing (GBS) data

Calleja-Rodriguez, A.; Pan, J.; Funda, T.; Chen, Z.-q.; Baison, J.; Isik, F.; Abrahamsson, S.; Wu, H. X.

10.1101/607648 — genetics — Posted on 2019-04-12

1864 Confinement and reversibility of threshold-dependent gene drive systems in spatially-explicit Aedes aegypti populations

Sanchez C., H. M.; Bennett, J. B.; Wu, S. L.; Rasic, G.; Akbari, O. S.; Marshall, J. M.

10.1101/607267 — ecology — Posted on 2019-04-12

1865 PRDM1 controls the sequential activation of neural, neural crest and sensory progenitor determinants by regulating histone modification

Prajapati, R. S.; Hintze, M.; Streit, A.

10.1101/607739 — developmental biology — Posted on 2019-04-12

1866 Developmentally regulated tcf7l2 splice variants mediate transcriptional repressor functions during eye formation

Young, R. M.; Ewan, K. B.; Ferrer, V. P.; Allende, M. L.; Dale, T. C.; Wilson, S. W.

10.1101/607713 — developmental biology — Posted on 2019-04-12

1867 Thick perirenal fat predicts the growth pattern of renal cell carcinoma

Kashiwagi, E.; Abe, T.; Kinoshita, F.; Imada, K.; Monji, K.; Shiota, M.; Takeuchi, A.; Inokuchi, J.; Tatsugami, K.; Eto, M.

10.1101/606624 — cancer biology — Posted on 2019-04-12

1868 The Neural Consequences of Attentional Prioritization of Internal Representations in Visual Working Memory

Sahan, M. I.; Sheldon, A. D.; Postle, B. R.

10.1101/606665 — neuroscience — Posted on 2019-04-12

1869 Longitudinal white matter development in children is associated with puberty, attentional difficulties, and mental health

Genc, S.; Malpas, C.; Gulenc, A.; Sciberras, E.; Efron, D.; Silk, T.; Seal, M.

10.1101/607671 — neuroscience — Posted on 2019-04-12

1870 Generalization asymmetry in multivariate cross-classification: When representation A generalizes better to representation B than B to A

van den Hurk, J.; Op de Beeck, H. P.

10.1101/592410 — neuroscience — Posted on 2019-04-12

1871 EPAC2 is required for corticotropin-releasing hormone-mediated spine loss

Xie, Z.; Penzes, P.; Srivastava, D. P.

10.1101/607598 — neuroscience — Posted on 2019-04-12

1872 Untangling featural and conceptual object representations

Grootswagers, T.; Robinson, A.; Shatek, S. M.; Carlson, T. A.

10.1101/607499 — neuroscience — Posted on 2019-04-12

1873 In Vitro Potent Activity of ε-poly-L-lysine against Candida albicans and the Underlying Mechanisms

Wei, L.; Yu, T.; Wang, X.; Hou, J.-x.; Wang, X.; Wang, C.; Li, K.; Jing, S.; Zhang, X.

10.1101/605857 — microbiology — Posted on 2019-04-12

1874 The BLIMP1 - EZH2 nexus in a non-Hodgkin lymphoma

Anderson, K. J.; Osvaldsdottir, A. B.; Atzinger, B.; Traustadottir, G. A.; Nolling Jensen, K.; Larusdottir, A. E.; Bergthorsson, J. T.; Harthardottir, I.; Magnusdottir, E.

10.1101/606749 — cancer biology — Posted on 2019-04-12

1875 Noda-like RNA viruses infecting Caenorhabditis nematodes: sympatry, diversity and reassortment

Frezal, L.; Jung, H.; Tahan, S.; Wang, D.; Felix, M.-A.

10.1101/605840 — microbiology — Posted on 2019-04-12

1876 Alpha-band oscillations reflect external spatial coding for tactile stimuli in sighted, but not in congenitally blind humans

Schubert, J. T. W.; Buchholz, V. N.; Foecker, J.; Engel, A. K.; Roder, B.; Heed, T.

10.1101/442384 — neuroscience — Posted on 2019-04-12

1877 Consolidation promotes rule discovery rather than semantic abstraction

Matorina, N.; Poppenk, J.

10.1101/578492 — neuroscience — Posted on 2019-04-12

1878 Reduced chromatin accessibility underlies gene expression differences in homologous chromosome arms of hexaploid wheat and diploid Aegilops tauschii

Lu, F.-H.; McKenzie, N.; Gardiner, L.-J.; Luo, M.; Hall, A.; Bevan, M. W.

10.1101/571133 — genomics — Posted on 2019-04-12

1879 Carnivore endozoochory of a dry-fruited tree can benefit quarry passive restoration

Salgueiro, V.; Silva, C.; Eufrazio, S.; Salgueiro, P. A.; Vaz, P. G.

10.1101/561142 — ecology — Posted on 2019-04-12

1880 Multiple two-photon targeted whole-cell patch-clamp recordings from monosynaptically connected neurons in vivo

Jouhanneau, J.-S.; Poulet, J. F. A.

10.1101/516708 — neuroscience — Posted on 2019-04-12

1881 Seasonal food availability calendars and dietary patterns for Dedza and Balaka districts: A comparative study

Zimba, T. R.; Mwangwela, A. M.; Mtimuni, B.; Chisala, P. W.

10.1101/607606 — ecology — Posted on 2019-04-12

1882 Evidence for the role of extrusomes in evading attack by the host immune system in a scuticociliate parasite

Leiro, J. M.; Folgueira, I.; Lamas, J.; de Felipe, A. P. P.; Sueiro, R. A.

10.1101/607622 — microbiology — Posted on 2019-04-12

1883 Seston fatty acids to quantify phytoplankton functional groups and their spatiotemporal dynamics in a highly turbid estuary

Canavate, J. P.; Van Bergeijk, S.; Gonzalez-Ortegon, E.; Vilas, C.

10.1101/607614 — ecology — Posted on 2019-04-12

1884 Heterologous Expression Pediocin PA-1 in Escherichia coli

Dang Thi, P. T.; Nguyen Pham, T. A.

10.1101/607630 — bioengineering — Posted on 2019-04-12

1885 Focal adhesion kinase confers pro-migratory and anti apoptotic properties and is a potential therapeutic target in Ewing sarcoma

Steinestel, K.; Jansen, E.-P.; Trautmann, M.; Dirksen, U.; Rehkamper, J.; Mikesch, J.-H.; Gerke, J. S.; Orth, M. F.; Sannino, G.; Wardelmann, E.; Grunewald, T. G. P.; Hartmann, W.

10.1101/604207 — cancer biology — Posted on 2019-04-12

1886 Disambiguating the role of blood flow and global signal with Partial Information Decomposition

Colenbier, N.; Van de Steen, F.; Uddin, L.; Poldrack, R.; Calhoun, V.; Marinazzo, D.

10.1101/596247 — neuroscience — Posted on 2019-04-12

1887 Modulating dream experience: Noninvasive brain stimulation over the sensorimotor cortex reduces dream movement

Noreika, V.; Windt, J. M.; Kern, M.; Valli, K.; Salonen, T.; Parkkola, R.; Revonsuo, A.; Karim, A. A.; Ball, T.; Lenggenhager, B.

10.1101/600288 — neuroscience — Posted on 2019-04-12

1888 What, if anything, is the true neurophysiological significance of rotational dynamics?

Lebedev, M. A.; Ossadtchi, A.; Adell Mill, N.; Armengol Urpi, N.; Cervera, M. R.; Nicolelis, M. A.

10.1101/597419 — neuroscience — Posted on 2019-04-12

1889 Destabilization of the tumor-inducing plasmid from an octopine-type Agrobacterium tumefaciens lineage drives a large deletion in the co-resident At megaplasmid

Barton, I. S.; Platt, T. G.; Rusch, D. B.; Fuqua, C.

10.1101/600809 — microbiology — Posted on 2019-04-12

1890 Genetic screens identify multiple negative regulators that additively restrict recruitment of the SWI/SNF chromatin remodeler to the HO promoter in Saccharomyces cerevisiae

Parnell, E. J.; Stillman, D. J.

10.1101/606780 — genetics — Posted on 2019-04-12

1891 Integrative taxonomy confirms the species status of the Himalayan langurs, Semnopithecus schistaceus Hodgson 1840

Arekar, K.; S, S.; Karanth, P.

10.1101/602243 — evolutionary biology — Posted on 2019-04-12

1892 Accelerated evolution of oligodendrocytes in human brain

Berto, S.; Mendizabal, I.; Usui, N.; Toriumi, K.; Chatterjee, P.; Douglas, C.; Tamminga, C.; Preuss, T.; Yi, S.; Konopka, G.

10.1101/601062 — evolutionary biology — Posted on 2019-04-12

1893 Chemically-defined induction of a primitive endoderm and epiblast-like niche supports post-implantation progression from blastoids.

Vrij, E. J.; Scholte Op Reimer, Y.; Frias Aldeguer, J.; Misteli Guerreiro, I.; Kind, J.; Koo, B.-K.; van Blitterswijk, C.; Rivron, N.

10.1101/510396 — developmental biology — Posted on 2019-04-12

1894 Time resolved quantitative phosphoproteomics reveals distinct patterns of SHP2 dependence in EGFR signaling

Vemulapalli, V.; Chylek, L.; Erickson, A.; LaRochelle, J.; Subramanian, K.; Mohseni, M.; LaMarche, M.; Acker, M. G.; Sorger, P. K.; Gygi, S. P.; Blacklow, S. C.

10.1101/598664 — cell biology — Posted on 2019-04-12

1895 The Alzheimer’s Disease Metabolome: Effects of Sex and APOE ε4 genotype

10.1101/585455 — bioinformatics — Posted on 2019-04-12

1896 In silico analysis of coding SNPs and 3-UTR associated miRNAs in DCAF17 gene that may affect the regulation and pathogenesis of Woodhouse-Sakati Syndrome

abdelmoneim, a. h.; Elrashied, A. M.; Mohammed, A. I.; Mirghani, S. A.; Osman, R. E.; Gadim, E. O.; Hassan, M. A.

10.1101/601310 — bioinformatics — Posted on 2019-04-12

1897 A stochastic spatial model for heterogeneity in cancergrowth

Queiroga, A. S.; de Morais, M. C. C.; Tortelli, T. C.; Chammas, R.; Ramos, A. F.

10.1101/584573 — systems biology — Posted on 2019-04-11

1898 tealeaves: an R package for modelling leaf temperature using energy budgets

Muir, C. D.

10.1101/529487 — plant biology — Posted on 2019-04-11

1899 A high-throughput delayed fluorescence method reveals underlying differences in the control of circadian rhythms in Triticum aestivum and Brassica napus

Rees, H.; Duncan, S.; Gould, P.; Wells, R.; Greenwood, M.; Brabbs, T.; Hall, A.

10.1101/570572 — plant biology — Posted on 2019-04-12

1900 Inhibition of the Dead Box RNA Helicase 3 prevents HIV-1 Tat and cocaine-induced neurotoxicity by targeting microglia activation

Aksenova, M.; Sybrandt, J.; Cui, B.; Sikirzhytski, V.; Ji, H.; Odhiambo, D.; Lucius, M. D.; Turner, J. R.; Broude, E.; Pena, E.; Lizarraga, S.; Zhu, J.; Safro, I.; Wyatt, M. D.; Shtutman, M.

10.1101/591438 — neuroscience — Posted on 2019-04-11

1901 Brain meta-state transitions demarcate spontaneous thoughts in movie-viewing and resting cognition

Tseng, J.; Poppenk, J.

10.1101/576298 — neuroscience — Posted on 2019-04-11

1902 Evolutionary pathways to antibiotic resistance are dependent upon environmental structure and bacterial lifestyle

Santos-Lopez, A.; Marshall, C. W.; Scribner, M. R.; Snyder, D.; Cooper, V. S.

10.1101/581611 — microbiology — Posted on 2019-04-12

1903 Interleukin 17 and senescence regulate the foreign body response

Chung, L.; Maestas, D.; Lebid, A.; Mageau, A.; Rosson, G. D.; Wu, X.; Wolf, M. T.; Tam, A.; Wang, X.; Vanderzee, I.; Andorko, J. I.; Narain, R.; Sadtler, K.; Fan, H.; Cihakova, D.; Jourdan Le Saux, C.; Housseau, F.; Pardoll, D. M.; Elisseeff, J.

10.1101/583757 — immunology — Posted on 2019-04-11

1904 Exon-mediated activation of transcription starts

Fiszbein, A.; Krick, K. S.; Burge, C. B.

10.1101/565184 — genomics — Posted on 2019-04-11

1905 Population histories of the United States revealed through fine-scale migration and haplotype analysis

Dai, C. L.; Vazifeh, M. M.; Yeang, C.-H.; Tachet, R.; Wells, R. S.; Vilar, M. G.; Daly, M. J.; Ratti, C.; Martin, A. R.

10.1101/577411 — genetics — Posted on 2019-04-11

1906 Virtual Microbes evolve multiple mechanisms to the same end: anticipating a serial transfer protocol

van Dijk, B.; Meijer, J.; Cuypers, T. D.; Hogeweg, P.

10.1101/554766 — evolutionary biology — Posted on 2019-04-11

1907 BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila

Ueberschar, M.; Wang, H.; Zhang, C.; Kondo, S.; Aoki, T.; Schedl, P. D.; Lai, E.; Wen, J.; Dai, Q.

10.1101/593830 — developmental biology — Posted on 2019-04-11

1908 CCL5 promotes breast cancer recurrence through macrophage recruitment in residual tumors

Walens, A.; DiMarco, A. V.; Lupo, R.; Kroger, B. R.; Damrauer, J. S.; Alvarez, J. V.

10.1101/584979 — cancer biology — Posted on 2019-04-11

1909 Systematic and comprehensive benchmarking of an exome sequencing based germline copy-number variant detection pipeline in a clinical setting

Rajagoapalan, R.; Murrell, J.; Jayaraman, P.; Wu, C.; Luo, M.; Conlin, L. K.

10.1101/579755 — bioinformatics — Posted on 2019-04-11

1910 A Truly Injectable Neural Stimulation Electrode Made from an In-Body Curing Polymer/Metal Composite

10.1101/584995 — bioengineering — Posted on 2019-04-11

1911 N-chlorination mediates protective and immunomodulatory effects of oxidized human plasma proteins

Ulfig, A.; Schulz, A. V.; Müller, A.; Lupilov, N.; Leichert, L. I.

10.1101/584961 — biochemistry — Posted on 2019-04-11

1912 Quantification of very low-abundant proteins in bacteria using the HaloTag and epi-fluorescence microscopy

Talyor, H.; Lepore, A.; Landgraf, D.; Okumus, B.; Jaramillo-Riveri, S.; McLaren, L.; Bakshi, S.; Paulsson, J.; El Karoui, M.

10.1101/237248 — systems biology — Posted on 2019-04-11

1913 Root caries on a Paranthropus robustus third molar from Drimolen

Towle, I.; Riga, A.; Irish, J. D.; Dori, I.; Menter, C.; Moggi-Cecchi, J.

10.1101/573964 — paleontology — Posted on 2019-04-11

1914 Forward modelling reveals dynamics of neural orientation tuning to unconscious visual stimuli during binocular rivalry

Tang, M. F.; Arabzadeh, E.; Mattingley, J. B.

10.1101/574905 — neuroscience — Posted on 2019-04-11

1915 Discovery of small alarmone synthetases and their inhibitors as toxin-antitoxin loci

Jimmy, S.; Saha, C. K.; Stavropoulos, C. G.; Garcia-Pino, A.; Hauryliuk, V.; Atkinson, G. C.

10.1101/575399 — microbiology — Posted on 2019-04-11

1916 Horizontally transmitted symbiont populations in deep-sea mussels are genetically isolated

Romero Picazo, D.; Dagan, T.; Ansorge, R.; Petersen, J. M.; Dubilier, N.; Kupczok, A.

10.1101/536854 — microbiology — Posted on 2019-04-11

1917 An integrative approach identifies direct targets of the late viral transcription complex and an expanded promoter recognition motif in Kaposi’s sarcoma-associated herpesvirus

Nandakumar, D.; Glaunsinger, B.

10.1101/550772 — microbiology — Posted on 2019-04-11

1918 Genomic analysis of the four ecologically distinct cactus host populations of Drosophila mojavensis

Allan, C. W.; Matzkin, L. M.

10.1101/530154 — genomics — Posted on 2019-04-11

1919 Extinctions in the marine plankton preceded by stabilizing selection

Weinkauf, M. F. G.; Bonitz, F. G. W.; Martini, R.; Kucera, M.

10.1101/531947 — ecology — Posted on 2019-04-11

1920 Prey abundance drives habitat occupancy by jaguars in Amazonian floodplain river islands

Rabelo, R. M.; Aragon, S.; Bicca-Marques, J. C.

10.1101/555052 — ecology — Posted on 2019-04-11

1921 Replication timing alterations in leukemia reflect stable clinically-relevant changes in genome architecture

Rivera-Mulia, J. C.; Sasaki, T.; Trevilla-Garcia, C.; Nakamichi, N.; Knapp, D. J. H. F.; Hammond, C.; Chang, B.; Tyner, J. W.; Devidas, M.; Zimmerman, J.; Klein, K.; Somasundaram, V.; Druker, B.; Gruber, T.; Koren, A.; Eaves, C. J.; Gilbert, D. M.

10.1101/549196 — cancer biology — Posted on 2019-04-11

1922 SyRI: identification of syntenic and rearranged regions from whole-genome assemblies

Goel, M.; Sun, H.; Jiao, W.-B.; Schneeberger, K.

10.1101/546622 — bioinformatics — Posted on 2019-04-11

1923 Detecting RyR clusters with CaCLEAN: influence of spatial distribution and structural heterogeneity

Ladd, D.; Tilunaite, A.; Soeller, C.; Roderick, H. L.; Crampin, E.; Rajagopal, V.

10.1101/549683 — bioengineering — Posted on 2019-04-11

1924 Microsecond Interaural Time Difference Discrimination Restored by Cochlear Implants After Neonatal Deafness

Rosskothen-Kuhl, N.; Buck, A. N.; Li, K.; Schnupp, J. W.

10.1101/498105 — neuroscience — Posted on 2019-04-11

1925 Neocortical layer 4 in adult mouse differs in major cell types and circuit organization between primary sensory areas

Scala, F.; Kobak, D.; Shan, S.; Bernaerts, Y.; Laturnus, S.; Cadwell, C. R.; Hartmanis, L.; Froudarakis, E.; Castro, J.; Tan, Z. H.; Papadopoulos, S.; Patel, S.; Sandberg, R.; Berens, P.; Jiang, X.; Tolias, A. S.

10.1101/507293 — neuroscience — Posted on 2019-04-11

1926 Prediction of pyrazinamide resistance in Mycobacterium tuberculosis using structure-based machine learning approaches.

Carter, J.; Walker, T. M.; Walker, A. S.; Whitfield, M.; Morlock, G. P.; Peto, T. E.; Posey, J. E.; Crook, D. W.; Fowler, P. W.

10.1101/518142 — microbiology — Posted on 2019-04-11

1927 Extensive post-transcriptional buffering of gene expression in the response to oxidative stress in baker yeast

Blevins, W. R.; Tavella, T.; Moro, S. G.; Blasco-Moreno, B.; Closa-Mosquera, A.; Diez, J.; Carey, L. B.; Alba, M. M.

10.1101/501478 — genomics — Posted on 2019-04-11

1928 Alveolar macrophage chromatin is modified to orchestrate host response to Mycobacterium bovis infection

Hall, T. J.; Vernimmen, D.; Browne, J. A.; Mullen, M. P.; Gordon, S. V.; MacHugh, D. E.; O'Doherty, A. M.

10.1101/520098 — genomics — Posted on 2019-04-11

1929 MGDrivE: A modular simulation framework for the spread of gene drives through spatially-explicit mosquito populations

Sanchez C., H. M.; Wu, S. L.; Bennett, J. B.; Marshall, J. M.

10.1101/350488 — genetics — Posted on 2019-04-11

1930 Makorin1 controls embryonic patterning by alleviating Bruno-mediated repression of oskar translation

Dold, A.; Han, H.; Liu, N.; Hildebrandt, A.; Brüggemann, M.; Rückle, C.; Busch, A.; Beli, P.; Zarnack, K.; König, J.; Roignant, J.-Y.; Lasko, P.

10.1101/501643 — developmental biology — Posted on 2019-04-11

1931 An ER CREC family protein regulates the egress proteolytic cascade in malaria parasites

Fierro, M. A.; Asady, B.; Brooks, C. F.; Villegas, A.; Moreno, S. N. J.; Muralidharan, V.

10.1101/457481 — cell biology — Posted on 2019-04-11

1932 An individual-based mechanical model of cell movement in heterogeneous tissues and its coarse-grained approximation

Murphy, R.; Buenzli, P.; Baker, r. E.; Simpson, M. J.

10.1101/485276 — biophysics — Posted on 2019-04-11

1933 Beyond power: Multivariate discovery, replication, and interpretation of pleiotropic loci using summary association statistics

Ning, Z.; Tsepilov, Y. A.; Sharapov, S. Z.; Grishenko, A. K.; Feng, X.; Shirali, M.; Joshi, P. K.; Wilson, J. F.; Pawitan, Y.; Haley, C. S.; Aulchenko, Y. S.; Shen, X.

10.1101/022269 — genetics — Posted on 2019-04-11

1934 Comparison of different extraction kits to isolate microRNA from Galleria mellonella (wax moth) larvae infected with Metarhizium brunneum (ARSEF4556)

Alenezi, M. A.; Butt, T. M.; Eastwood, D. C.

10.1101/606004 — molecular biology — Posted on 2019-04-11

1935 Hepatocellular carcinoma computational models identify key protein-complexes associated to tumor progression

Folschette, M.; Legagneux, V.; Poret, A.; Guziolowski, C.; Theret, N.

10.1101/605519 — systems biology — Posted on 2019-04-11

1936 Shifting from fear to safety through deconditioning-update: a novel approach to attenuate fear memories

Popik, B.; Amorim, F. E.; Amaral, O. B.; de Oliveira Alvares, L.

10.1101/605196 — neuroscience — Posted on 2019-04-11

1937 Patronus is the elusive plant securin, preventing chromosome separation by antagonizing separase

Cromer, L.; Jolivet, S.; Singh, D. K.; Berthier, F.; De Winne, N.; De Jaeger, G.; Komaki, S.; Prusicki, M. A.; Schnittger, A.; Guerois, R.; Mercier, R.

10.1101/606285 — cell biology — Posted on 2019-04-11

1938 MetaNovo: a probabilistic approach to peptide and polymorphism discovery in complex mass spectrometry datasets

Potgieter, M. G.; Nel, A. J.; Tabb, D. L.; Fortuin, S.; Garnett, S.; Blackburn, J.; Mulder, N.

10.1101/605550 — bioinformatics — Posted on 2019-04-11

1939 CRISPR-GNL: an improved model for predicting CRISPR activity by machine learning and featurization

Zhang, X.; Wang, J.; Luo, Y.; Xi, X.; LiXin, C.

10.1101/605790 — bioinformatics — Posted on 2019-04-11

1940 Interplay between gene nucleotide composition bias and splicing

Lemaire, S.; Fontrodona, N.; Claude, J.-B.; Polveche, H.; Aube, F.; Modolo, L.; Bourgeois, C.; Mortreux, F.; Auboeuf, D.

10.1101/605832 — molecular biology — Posted on 2019-04-11

1941 Integrating regulatory DNA sequence and gene expression to predict genome-wide chromatin accessibility across cellular contexts

Nair, S.; Kim, D. S.; Perricone, J.; Kundaje, A.

10.1101/605717 — genomics — Posted on 2019-04-11

1942 U-PASS: unified power analysis and forensics for qualitative traits in genetic association studies

Gao, Z.; Terhorst, J.; Van Hout, C.; Stoev, S.

10.1101/605766 — genetics — Posted on 2019-04-11

1943 Environmental drivers define contrasting microbial habitats, diversity and functional redundancy in Lake Baikal, Siberia

Wilburn, P.; Shchapov, K.; Theriot, E. C.; Litchman, E.

10.1101/605899 — ecology — Posted on 2019-04-11

1944 Endocrine, metabolic, and endocannabinoid alterations in rats exhibiting high anxiety-related behaviors

Vega-Torres, J. D.; Kalyan-Masih, P.; Argueta, D. A.; DiPatrizio, N. V.; Figueroa, J. D.

10.1101/605329 — animal behavior and cognition — Posted on 2019-04-11

1945 De novo transcriptome sequencing of Serangium japonicum (Coleoptera: Coccinellidae) and application of two assembled unigenes

Hu, Y. H.; Liu, Y.; Wei, L.; Chen, H. T.

10.1101/605410 — zoology — Posted on 2019-04-11

1946 Extended categorization of conjunction object stimuli decreases the latency of attentional feature selection and recruits orthography-linked ERPs

Folstein, J. R.; Monfared, S. S.

10.1101/605360 — neuroscience — Posted on 2019-04-11

1947 Imaging toxin-induced neuroinflammation in mice using hyperpolarized 13C magnetic resonance spectroscopy

Le Page, L. M.; Guglielmetti, C.; Najac, C. F.; Tiret, B.; Chaumeil, M. M.

10.1101/605568 — immunology — Posted on 2019-04-11

1948 Neutrophils use selective autophagy receptor p62 to target Staphylococcus aureus for degradation in the zebrafish model

Gibson, J. F.; Prajsnar, T. K.; Serba, J. J.; Tonge, R. D.; Grierson, A. J.; Ingham, P. W.; Renshaw, S. A.; Johnston, S. A.

10.1101/604884 — immunology — Posted on 2019-04-11

1949 CRISPR-Cas9-assisted native end-joining editing offers a simple strategy for efficient genetic engineering in Escherichia coli

Huang, C.; Ding, T.; Wang, J.; Wang, X.; Wang, J.; Zhu, L.; Bi, C.; Zhang, X.; Ma, X.; huo, y.

10.1101/605246 — bioengineering — Posted on 2019-04-11

1950 Dynamic changes in Anterior Cingulate Cortex ensembles mark the transition from exploration to exploitation

Emberly, E.; Seamans, J. K.

10.1101/605592 — neuroscience — Posted on 2019-04-11

1951 Sex differences in chronic social stress models in mice

Furman, O.; Tsoory, M.; Chen, A.

10.1101/605527 — neuroscience — Posted on 2019-04-11

1952 Disruption of genes associated with Charcot-Marie-Tooth type 2 lead to common behavioural, cellular and molecular defects in Caenorhabditis elegans

Soh, M. S.; Cheng, X.; Liu, J.; Neumann, B.

10.1101/605584 — neuroscience — Posted on 2019-04-11

1953 Parsers, Data Structures and Algorithms for Macromolecular Analysis Toolkit (MAT): Design and Implementation

Kalyan, G.; Junghare, V.; S, J.; Chattopadhyay, A.; Mitra, P.; Hazra, S.

10.1101/605907 — bioinformatics — Posted on 2019-04-11

1954 An evidence-based network approach to recommending targeted cancer therapies

Kancherla, J.; Rao, S.; Bhuvaneshwar, K.; Riggins, R. B.; Beckman, R. A.; Madhavan, S.; Corrada Bravo, H.; Boca, S. M.

10.1101/605261 — bioinformatics — Posted on 2019-04-11

1955 Blue carbon sequestration dynamics within a tropical seagrass sediment: Long term incubations for changes over climatic scales

Chuan, C. H.; Gallagher, J. B.; Chew, S. T.; Mohd. Zanuri, N. B.

10.1101/604587 — plant biology — Posted on 2019-04-11

1956 An epigenome-wide association study of sex-specific chronological ageing

McCartney, D. L.; Hillary, R. F.; Zhang, Q.; Stevenson, A. J.; Walker, R. M.; Bermingham, M. L.; Morris, S. W.; Campbell, A.; Murray, A. D.; Whalley, H. C.; Porteous, D. J.; Evans, K. L.; Chandra, T.; Deary, I. J.; McIntosh, A. M.; Visscher, P. M.; McRae, A. F.; Marioni, R. E.

10.1101/606020 — genomics — Posted on 2019-04-11

1957 Monitoring contractility in single cardiomyocytes and whole hearts with bio-integrated microlasers

Schubert, M.; Woolfson, L.; Barnard, I. R.; Morton, A.; Casement, B.; Robertson, G. B.; Miles, G. B.; Pitt, S. J.; Tucker, C. S.; Gather, M. C.

10.1101/605444 — biophysics — Posted on 2019-04-11

1958 BreakCA, a method to discover indels using ChIP-seq and ATAC-seq reads, finds recurrent indels in regulatory regions of neuroblastoma genomes

Sen, A.; Tyndale, S. T.; Fu, Y.; Erikson, G.; McVicker, G.

10.1101/605642 — bioinformatics — Posted on 2019-04-11

1959 Light-sheet microscopy with isotropic, sub-micron resolution and solvent-independent large-scale imaging

Chakraborty, T.; Driscoll, M.; Murphy, M. M.; Roudot, P.; Chang, B.-J.; Vora, S.; Wong, W. M.; Nielson, C.; Zhang, H.; Zhemkov, V.; Hiremath, C.; De La Cruz, E. D.; Bezprozvanny, I.; Zhao, H.; Tomer, R.; Heintzmann, R.; Meeks, J.; Marciano, D.; Morrison, S.; Danuser, G.; Dean, K.; Fiolka, R.

10.1101/605493 — bioengineering — Posted on 2019-04-11

1960 RICOPILI: Rapid Imputation for COnsortias PIpeLIne

Lam, M.; Awasthi, S.; Watson, H.; Goldstein, J.; Panagiotaropoulou, G.; Trubetskoy, V.; Karlsson, R.; Frei, O.; Fan, C.-C.; De Witte, W.; Mota, N. R.; Mullins, N.; Skarabis, N.; Huang, H.; Neale, B.; Daly, M.; Mattheissen, M.; Walters, R.; Ripke, S.

10.1101/587196 — genetics — Posted on 2019-04-11

1961 Modelling the On-going Natural Selection of Educational Attainment in Contemporary Societies

Hong, Z.

10.1101/605311 — evolutionary biology — Posted on 2019-04-11

1962 Toxicity drives facilitation between four bacterial species

Piccardi, P.; Vessman, B.; Mitri, S.

10.1101/605287 — ecology — Posted on 2019-04-11

1963 Structural basis for inhibition of human primase by arabinofuranosyl nucleoside analogues Fludarabine and Vidarabine

Holzer, S.; Rzechorzek, N. J.; Short, I. R.; Jenkyn-Bedford, M.; Pellegrini, L.; Kilkenny, M. L.

10.1101/605279 — biochemistry — Posted on 2019-04-11

1964 A microtubule-mediated mechanical feedback controls leaf blade development in three dimensions

Zhao, F.; Du, F.; Oliveri, H.; Zhou, L.; Ali, O.; Chen, W.; Feng, S.; Wang, Q.; Lü, S.; Long, M.; Schneider, R.; Sampathkumar, A.; Godin, C.; Traas, J.; Jiao, Y.

10.1101/604710 — developmental biology — Posted on 2019-04-11

1965 Natural hypothalamic circuit dynamics underlying object memorization

Kosse, C.; Burdakov, D.

10.1101/603936 — neuroscience — Posted on 2019-04-11

1966 The connectome is necessary but not sufficient for the spread of alpha-synuclein pathology in rats

Oliveira, M. A.; Arreckx, S.; Di Monte, D.; Preciat Gonzalez, G. A.; Ulusoy, A.; Fleming, R. M.

10.1101/567222 — neuroscience — Posted on 2019-04-11

1967 Validity and reliability of extrastriatal raclopride binding quantification in the living human brain

Svensson, J.; Schain, M.; Plaven-Sigray, P.; Cervenka, S.; Tiger, M.; Nord, M.; Halldin, C.; Farde, L.; Lundberg, J.

10.1101/600080 — neuroscience — Posted on 2019-04-11

1968 Development of Pavlovian-to-instrumental transfer (PIT) task to examine the effects of reward-predicting cues on behavioral activation in young adults

da Costa, R. Q. M.; Furukawa, E.; Hoefle, S.; Moll, J.; Tripp, G.; Mattos, P.

10.1101/601195 — neuroscience — Posted on 2019-04-11

1969 Macroevolutionary integration of phenotypes within and across ant worker castes

Friedman, N. R.; Bennet, B. L.; Fischer, G.; Sarnat, E. M.; Huang, J.-P.; Knowles, L. L.; Economo, E. P.

10.1101/604470 — evolutionary biology — Posted on 2019-04-11

1970 Scalable data analysis in proteomics and metabolomics using BioContainers and workflows engines.

Perez-Riverol, Y.; Moreno, P.

10.1101/604413 — bioinformatics — Posted on 2019-04-11

1971 Interdisciplinary and disciplinary identities: towards a theory of forms of knowledge change

Van den Besselaar, P.

10.1101/603449 — scientific communication and education — Posted on 2019-04-11

1972 Bean yellow mosaic virus infecting broad bean in the green belt of Cordoba, Argentina

Rodriguez Pardina, P.; Nome, C.; Reyna, P.; Munoz, N.; Arguello Caro, E.; Luque, A.; Debat, H. J.

10.1101/606384 — microbiology — Posted on 2019-04-11

1973 A resource-efficient tool for mixed model association analysis of large-scale data

Jiang, L.; Zheng, Z.; Qi, T.; Kemper, K. E.; Wray, N. R.; Visscher, P. M.; Yang, J.

10.1101/598110 — genetics — Posted on 2019-04-11

1974 Molecular archaeology of the human brain

Kaczanowska, J.; Ganglberger, F.; Galik, B.; Hess, A.; Moodley, Y.; Buehler, K.; Haubensak, W.

10.1101/598094 — bioinformatics — Posted on 2019-04-11

1975 Dynamic cerebral autoregulation of endurance-trained men following 6 weeks of high-intensity interval training to exhaustion

Drapeau, A.; Labrecque, L.; Imhoff, S.; Paquette, M.; Le Blanc, O.; Malenfant, S.; Brassard, P.

10.1101/605667 — physiology — Posted on 2019-04-11

1976 A fence function for adherens junctions in epithelial cell polarity

Aguilar-Aragon, M.; Tournier, A.; Thompson, B. J.

10.1101/605808 — developmental biology — Posted on 2019-04-11

1977 Hyperactive TORC1 sensitizes yeast cells to endoplasmic reticulum stress by compromising cell wall integrity

Ahmed, K.; Carter, D. E.; Lajoie, P.

10.1101/605824 — cell biology — Posted on 2019-04-11

1978 γ-Linolenic acid increases expression of key regulators of lipid metabolism in human skeletal muscle cells.

Baker, L. A.; Martin, N. R. W.; Player, D. J.; Lewis, M. P.

10.1101/605949 — cell biology — Posted on 2019-04-11

1979 Loss of spatacsin impairs cholesterol trafficking and calcium homeostasis

Boutry, M.; Pierga, A.; Matusiak, R.; Branchu, J.; Houllegatte, M.; Ibrahim, Y.; Balse, E.; El Hachimi, K. H.; Brice, A.; Stevanin, G.; Darios, F.

10.1101/605964 — cell biology — Posted on 2019-04-11

1980 Automated Reconstruction of a Serial-Section EM Drosophila Brain with Flood-Filling Networks and Local Realignment

Li, P. H.; Lindsey, L. F.; Januszewski, M.; Zheng, Z.; Bates, A. S.; Taisz, I.; Tyka, M.; Nichols, M.; Li, F.; Perlman, E.; Maitin-Shepard, J.; Blakely, T.; Leavitt, L.; Jefferis, G. S. X. E.; Bock, D.; Jain, V.

10.1101/605634 — neuroscience — Posted on 2019-04-11

1981 The central role of the tail in switching off myosin II in cells

Craig, R.; Yang, S.; Lee, K. H.; Woodhead, J. L.; Sato, O.; Ikebe, M.

10.1101/606368 — cell biology — Posted on 2019-04-11

1982 Loss of adipocyte identity through synergistic repression of PPARγ by TGF-β and mechanical stress

Bielczyk-Maczynska, E.; Taylor, B.; Miller, C.; Zhao, M. L.; Shah, A.; Bahrami-Nejad, Z.; Dunn, A.; Teruel, M.

10.1101/604231 — cell biology — Posted on 2019-04-11

1983 Longitudinal stability of the brain functional connectome is associated with episodic memory performance in aging

Ousdal, O. T.; Kaufmann, T.; Kolskaar, K.; Vik, A.; Wehling, E.; Lundervold, A. J.; Lundervold, A.; Westlye, L.

10.1101/606178 — neuroscience — Posted on 2019-04-11

1984 Genetic screens identify multiple negative regulators that additively restrict recruitment of the SWI/SNF chromatin remodeler to the HO promoter in Saccharomyces cerevisiae

Parnell, E. J.; Stillman, D. J.

10.1101/606780 — genetics — Posted on 2019-04-11

1985 Proresolving mediators LXB4 and RvE1 regulate inflammation in stromal cells from patients with shoulder tendon tears

Dakin, S. G.; Colas, R. A.; Wheway, K.; Watkins, B.; Appleton, L.; Rees, J.; Gwilym, S.; Little, C.; Dalli, J.; Carr, A. J.

10.1101/606152 — cell biology — Posted on 2019-04-11

1986 Proton-control of transitions in an amino-acid transporter

Wu, Z.; Alibay, I.; Newstead, S.; Biggin, P. C.

10.1101/606913 — biophysics — Posted on 2019-04-11

1987 ADHD symptoms map onto noise-driven structure-function decoupling between hub and peripheral brain regions

Hearne, L.; Lin, H.-Y.; Sanz-Leon, P.; Tseng, W.-Y. I.; Gau, S. S.-F.; Roberts, J.; Cocchi, L.

10.1101/606228 — neuroscience — Posted on 2019-04-11

1988 Genome-wide Associations of Flavivirus Capsid Proteins

Huber, R. G.; Boon, P. L. S.; Martins, A. S.; Enguita, F. J.; Lim, X. N.; Santos, N. C.; Martins, I. C.; Wan, Y.; Bond, P.; Matsudaira, P. T.

10.1101/606905 — genomics — Posted on 2019-04-11

1989 Polygenic risk score based on weight gain trajectories is a strong predictor of childhood obesity

Craig, S. J. C.; Kenney, A. M.; Lin, J.; Paul, I. M.; Birch, L. L.; Savage, J.; Marini, M. E.; Chiaromonte, F.; Reimherr, M. L.; Makova, K. D.

10.1101/606277 — genetics — Posted on 2019-04-11

1990 Uncovering tissue-specific binding features from differential deep learning

Phuycharoen, M.; Zarrineh, P.; Bridoux, L.; Amin, S.; Chen, K.; Bobola, N.; Rattray, M.

10.1101/606269 — bioinformatics — Posted on 2019-04-11

1991 Selective translation by alternative bacterial ribosomes

Chen, Y.-X.; Xu, Z.-Y.; Wang, B.-W.; Ge, X.; Zhu, J.-H.; Sanyal, S.; Lu, Z. J.; Javid, B.

10.1101/605931 — microbiology — Posted on 2019-04-11

1992 Complex responses to inflammatory oxidants by the probiotic bacterium Lactobacillus reuteri

Basu Thakur, P.; Long, A. R.; Nelson, B. J.; Kumar, R.; Rosenberg, A. F.; Gray, M. J.

10.1101/605881 — microbiology — Posted on 2019-04-11

1993 Sustained organic loading perturbation inhibits nitrite oxidation in bioreactors, unveiling variable resistance and resilience of nitrification and nitrifiers

Santillan, E.; Phua, W. X.; Constancias, F.; Wuertz, S.

10.1101/605733 — microbiology — Posted on 2019-04-11

1994 Chemogenomic profiling of anti-leishmanial efficacy and resistance in the related kinetoplastid parasite Trypanosoma brucei

Collett, C. F.; Kitson, C.; Baker, N.; Steele-Stallard, H. B.; Santrot, M.-V.; Hutchinson, S.; Horn, D.; Alsford, S.

10.1101/605873 — microbiology — Posted on 2019-04-11

1995 Topological analysis of the type 3 secretion system translocon pore protein IpaC following its native delivery to the plasma membrane during infection

Russo, B. C.; Duncan, J. K.; Goldberg, M. B.

10.1101/605865 — microbiology — Posted on 2019-04-11

1996 Targeted Nanopore Sequencing with Cas9 for studies of methylation, structural variants and mutations

Gilpatrick, T.; Lee, I.; Graham, J. E.; Raimondeau, E.; Bowen, R.; Heron, A.; Sedlazeck, F.; Timp, W.

10.1101/604173 — genomics — Posted on 2019-04-11

1997 Putative cis-regulatory elements predict iron deficiency responses in Arabidopsis roots

Schwarz, B.; Azodi, C. B.; Shiu, S.-H.; Bauer, P.

10.1101/603290 — plant biology — Posted on 2019-04-11

1998 Differential nanoscale organisation of LFA-1 modulates T cell migration

Shannon, M.; Pineau, J.; Griffie, J.; Aaron, J.; Peel, T.; Williamson, D.; Zamoyska, R.; Cope, A.; Cornish, G.; Owen, D.

10.1101/602326 — immunology — Posted on 2019-04-11

1999 tRNA dissociation from EF-Tu after GTP hydrolysis and Pi release: primary steps and antibiotic inhibition

Warias, M.; Grubmuller, H.; Bock, L. V.

10.1101/602383 — biophysics — Posted on 2019-04-11

2000 High Throughput PET/CT Imaging Using a Multiple Mouse Imaging System

Greenwood, H. E.; Nyitrai, Z.; Mocsai, G.; Hobor, S.; Witney, T. H.

10.1101/602391 — bioengineering — Posted on 2019-04-11

2001 ViraMiner: deep learning on raw DNA sequences for identifying viral genomes in human samples

Tampuu, A.; Bzhalava, Z.; Dillner, J.; Vicente, R.

10.1101/602656 — bioinformatics — Posted on 2019-04-11

2002 Nectar- and stigma-specific expression of a chitinase could partially protect against fire blight in certain apples

Kurilla, A.; Timea Toth, T.; Dorgai, L.; Darula, Z.; Lakatos, T.; Silhavy, D.; Kerenyi, Z.; Dallmann, G.

10.1101/606046 — plant biology — Posted on 2019-04-11

2003 Single cell transcriptome analysis reveals markers of naive and lineage-primed hematopoietic progenitors derived from human pluripotent stem cells.

Fidanza, A.; Romano, N.; Ramchandran, P.; Tamagno, S.; Lopez-Yrigojen, M.; Taylor, H. A.; Easterbrook, J.; Henderson, B.; Axton, R.; Henderson, N. C.; Medvinsky, A.; Ottersbach, K.; Forrester, L. M.

10.1101/602565 — developmental biology — Posted on 2019-04-11

2004 Agreement between two large pan-cancer CRISPR-Cas9 gene dependency datasets

Dempster, J. M.; Pacini, C.; Pantel, S.; Behan, F. M.; Green, T.; Krill-Burger, J.; Beaver, C. M.; Zhivich, V.; Najgebauer, H.; Allen, F.; Goncalves, E.; Shepherd, R.; Doench, J. G.; Yusa, K.; Vazquez, F.; Parts, L.; Boehm, J. S.; Golub, T. R.; Hahn, W. C.; Root, D. E.; Garnett, M. J.; Iorio, F.; Tsherniak, A.

10.1101/604447 — cancer biology — Posted on 2019-04-11

2005 Nanotopography reveals metabolites that maintain the immunosuppressive phenotype of mesenchymal stem cells

Ross, E.; Turner, L.-A.; Saeed, A.; Burgess, K.; Blackburn, G.; Reynolds, P.; Wells, J.; Mountford, J.; Gadegaard, N.; Salmeron-Sanchez, M.; Oreffo, R.; Dalby, M.

10.1101/603332 — bioengineering — Posted on 2019-04-11

2006 Horizontal acquisition followed by expansion and diversification of toxin-related genes in deep-sea bivalve symbionts

Sayavedra, L.; Ansorge, R.; Rubin Blum, M.; Leisch, N.; Dubilier, N.; Petersen, J.

10.1101/605386 — microbiology — Posted on 2019-04-11

2007 Comparative genomics groups phages of Negativicutes and classical Firmicutes despite different Gram-staining properties

Rands, C. M.; Brussow, H.; Zdobnov, E. M.

10.1101/606087 — microbiology — Posted on 2019-04-11

2008 Neuropilin-1 regulates the secondary CD8 T cell response to virus infection

Hwang, J. Y.; Sun, Y.; Carroll, C. R.; Usherwood, E. J.

10.1101/605816 — immunology — Posted on 2019-04-11

2009 CRISPR/Cas9 Treatment Causes Extended TP53-Dependent Cell Cycle Arrest In Human Cells

Geisinger, J. M.; Stearns, T.

10.1101/604538 — genetics — Posted on 2019-04-11

2010 TRIM5α restricts flavivirus replication by targeting the viral protease for proteasomal degradation.

Chiramel, A. I.; Meyerson, N.; McNally, K.; Broeckel, R. M.; Montoya, V.; Mendes-Solis, O.; Robertson, S.; Sturdevant, G.; Lubick, K.; Nair, V.; Youseff, B.; Ireland, R.; Bosio, C.; Kim, K.; Luban, J.; Hirsch, V.; Taylor, T. R.; Bouamr, F.; Sawyer, S.; Best, S. M.

10.1101/605345 — microbiology — Posted on 2019-04-11

2011 A conserved protein, BcmA, mediates motility, biofilm formation, and host colonisation in Adherent Invasive Escherichia coli

Cogger-Ward, R.; Collins, A.; McLean, D.; Dehinsilu, J.; Huett, A.

10.1101/606798 — microbiology — Posted on 2019-04-11

2012 Eiger/TNFα-mediated Dilp8 and ROS production coordinate intra-organ growth in Drosophila

Sanchez, J. A.; Mesquita, D.; Ingaramo, M. C.; Ariel, F.; Milan, M.; Dekanty, A.

10.1101/606707 — developmental biology — Posted on 2019-04-11

2013 Differential Metabolic Sensitivity of mTORC1- and mTORC2-Dependent Overgrowth

Devilliers, M.; Garrido, D.; Poidevin, M.; Rubin, T.; Le Rouzic, A.; Montagne, J.

10.1101/606699 — cell biology — Posted on 2019-04-11

2014 Helminth infection-induced carcinogenesis: spectrometric insights from the liver flukes, Opisthorchis and Fasciola

Gouveia, M. J.; Pakharukova, M. Y.; Sripa, B.; Rinaldi, G.; Brindley, P. J.; Mordvinov, V. A.; Gärtner, F.; Costa, J. M. C. d.; Vale, N.

10.1101/606772 — cancer biology — Posted on 2019-04-11

2015 Machine Source Localization of Tursiops Truncatus Whistle-like Sounds in a Reverberant Aquatic Environment

Woodward, S. F.; Reiss, D.; Magnasco, M.

10.1101/606673 — biophysics — Posted on 2019-04-11

2016 CD4 T-cell transcriptome expression reversal of the lncRNA-mRNA co-expression network in elite controller vs. normal-process HIV patients

Chen, C.; Lu, X.; Wu, N.

10.1101/606731 — bioinformatics — Posted on 2019-04-11

2017 Automated detection of the HER2 gene amplification status in Fluorescence in situ hybridization images for the diagnostics of cancer tissues

Zakrzewski, F.; de Back, W.; Weigert, M.; Wenke, T.; Zeugner, S.; Mantey, R.; Sperling, C.; Friedrich, K.; Roeder, I.; Aust, D. E.; Baretton, G.; Hoenscheid, P.

10.1101/490052 — pathology — Posted on 2019-04-11

2018 Methamphetamine learning induces persistent nonmuscle myosin II-dependent spine motility in the basolateral amygdala

Young, E. J.; Lin, H.; Kamenecka, T. M.; Rumbaugh, G.; Miller, C. A.

10.1101/605394 — neuroscience — Posted on 2019-04-11

2019 A Human-Machine Coupled System for Efficient Sleep Spindle Detection by Iterative Revision

Bi, D.

10.1101/454488 — neuroscience — Posted on 2019-04-11

2020 Knockout of Babesia bovis rad51 ortholog and its complementation by expression from the BbACc3 artificial chromosome platform

Mack, E. A.; Xiao, Y.-P.; Allred, D.

10.1101/606590 — molecular biology — Posted on 2019-04-11

2021 Genome-wide developed microsatellites reveal a weak population differentiation in the hoverfly Eupeodes corollae (Diptera: Syrphidae) across China

deqiang, P.; Meng-Jia, L.; Wang, x.; ma, l.; cao, l.; liu, h.; Wei, S.

10.1101/606657 — molecular biology — Posted on 2019-04-11

2022 Multidimensional analysis of Gammaherpesvirus RNA expression reveals unexpected heterogeneity of gene expression

Oko, L. M.; Kimball, A. K.; Kaspar, R. E.; Knox, A. N.; Coleman, C. B.; Rochford, R.; Chang, T.; Alderete, B.; van Dyk, L. F.; Clambey, E. T.

10.1101/482042 — microbiology — Posted on 2019-04-11

2023 Innate CD8aa+ cells and osteopontin promote ILC1-like intraepithelial lymphocyte homeostasis and intestinal inflammation

Olivares-Villagomez, D.; Nazmi, A.; Hoek, K.; Greer, M.; Piazuelo, M. B.; Minato, N.

10.1101/606616 — immunology — Posted on 2019-04-11

2024 Factors associated with sharing email information and mental health survey participation in two large population cohorts

Adams, M.; Hill, W. D.; Howard, D. M.; Davis, K. A. S.; Deary, I. J.; Hotopf, M.; McIntosh, A. M.

10.1101/471433 — genetics — Posted on 2019-04-11

2025 Performance assessment of age-adapted SOFA, qSOFA, and PELOD-2, PCIS, P-MODS for Hand, Foot and Mouth Disease

yu, z.; Li, A.; Huang, T.; He, Z.; Chen, H.; Zhu, J.

10.1101/606574 — epidemiology — Posted on 2019-04-11

2026 Destabilizing evolutionary and eco-evolutionary feedbacks drive empirical eco-evolutionary cycles

Cortez, M.; Patel, S.; Schreiber, S.

10.1101/488759 — ecology — Posted on 2019-04-11

2027 Eye tracking-based estimation and compensation of chromatic offsets for multi-wavelength retinal microstimulation with foveal cone precision

Domdei, N.; Linden, M.; Reiniger, J. L.; Holz, F. G.; Harmening, W. M.

10.1101/599464 — biophysics — Posted on 2019-04-11

2028 A modified Rayleigh-Plesset equation for a liquid-crystalline shelled microbubble

Cowley, J.; Mulholland, A.; Gachagan, A.

10.1101/606632 — bioengineering — Posted on 2019-04-11

2029 Measurement of ocular transmission in living human eyes with a double-pass system

Sanchez, R.; de Paul, A.; Burgos-Fernandez, F.; Vilaseca, M.; Pujol, J.; Issolio, L.

10.1101/606640 — bioengineering — Posted on 2019-04-11

2030 Disruption of membrane cholesterol organization impairs the concerted activity of PIEZO1 channel clusters

Ridone, P.; Pandzic, E.; Vassalli, M.; Cox, C. D.; Macmillan, A.; Gottlieb, P. A.; Martinac, B.

10.1101/604488 — biophysics — Posted on 2019-04-11

2031 chromoMap: An R package for Interactive Visualization and Annotation of Chromosomes

Anand, L.

10.1101/605600 — bioinformatics — Posted on 2019-04-11

2032 Deciphering interaction fingerprints from protein molecular surfaces

Gainza, P.; Sverrisson, F.; Monti, F.; Rodola, E.; Bronstein, M. M.; Correia, B. E.

10.1101/606202 — bioinformatics — Posted on 2019-04-11

2033 Denoising High-field Multi-dimensional MRI with Local Complex PCA

Bazin, P.-L.; Alkemade, A.; van der Zwaag, W.; Caan, M.; Mulder, M.; Forstmann, B. U.

10.1101/606582 — bioinformatics — Posted on 2019-04-11

2034 Bayesian Estimation of Population Size Changes by Sampling Tajima’s Trees

Palacios, J. A.; Veber, A.; Cappello, L.; Wang, Z.; Wakeley, J.; Ramachandran, S.

10.1101/605352 — genetics — Posted on 2019-04-11

2035 Direct measurement of X-ray induced heating of microcrystals

Warren, A.; Axford, D.; Owen, R.

10.1101/603522 — biophysics — Posted on 2019-04-11

2036 Maintenance of spatial gene expression by Polycomb-mediated repression after formation of a vertebrate body plan

Rougot, J.; Chrispijn, N. D.; Aben, M.; Elurbe, D. M.; Andralojc, K. M.; Murphy, P. J.; Jansen, P. W.; Vermeulen, M.; Cairns, B. R.; Kamminga, L. M.

10.1101/468769 — developmental biology — Posted on 2019-04-11

2037 The Israeli Acute Paralysis Virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.

Fernandez, I.; Frank, J.; Acosta-Reyes, F.; Neupane, R.

10.1101/606236 — biophysics — Posted on 2019-04-11

2038 Dendritic spikes expand the range of well-tolerated population noise structures

Poleg-Polsky, A.

10.1101/454215 — neuroscience — Posted on 2019-04-11

2039 An Indexing Theory for Working Memory based on Fast Hebbian Plasticity

Fiebig, F.; Herman, P.; Lansner, A.

10.1101/334821 — neuroscience — Posted on 2019-04-11

2040 Representation Learning of Genomic Sequence Motifs with Convolutional Neural Networks

Koo, P. K.; Eddy, S. R.

10.1101/362756 — genomics — Posted on 2019-04-11

2041 Immuno-genomic Pan-cancer Landscape Reveals Diverse Immune Escape Mechanisms and Immuno-Editing Histories

10.1101/285338 — genomics — Posted on 2019-04-11

2042 A major role for common genetic variation in anxiety disorders

Purves, K. L.; Coleman, J. R. I.; Meier, S. M.; Rayner, C.; Davis, K. A. S.; Cheesman, R.; Baekvad-Hansen, M.; Borglum, A.; Choi, S. W.; Hettema, J. M.; Gaspar, H. A.; Bybjerg-Grauholm, J.; Hotopf, M.; Deckert, J.; Hougaard, D.; Kan, C.; Huebel, C.; Bo Mortensen, P.; Nordentoft, M.; Werge, T.; Mors, O.; McIntosh, A. M.; Nicodemus, K. K.; Mattheisen, M.; Breen, G.; Eley, T. C.

10.1101/203844 — genetics — Posted on 2019-04-11

2043 Network organization of antibody interactions in sequence and structure space: the RADARS model

Prechl, J.

10.1101/438804 — biophysics — Posted on 2019-04-11

2044 Gender and international diversity improves equity in peer review

Murray, D.; Siler, K.; Lariviere, V.; Chan, W. M.; Collings, A. M.; Raymond, J.; Sugimoto, C. R.

10.1101/400515 — scientific communication and education — Posted on 2019-04-11

2045 A novel mutant allele uncouples brassinosteroid-dependent and independent functions of BRI1

Holzwart, E.; Gloeckner, N.; Hoefte, H.; Harter, K.; Wolf, S.

10.1101/605923 — plant biology — Posted on 2019-04-11

2046 DART-ID increases single-cell proteome coverage

Chen, A. T.; Franks, A.; Slavov, N.

10.1101/399121 — bioinformatics — Posted on 2019-04-11

2047 neoepiscope Improves Neoepitope Prediction with Multi-variant Phasing

Wood, M. A.; Nguyen, A.; Struck, A. J.; Ellrott, K.; Nellore, A.; Thompson, R. F.

10.1101/418129 — bioinformatics — Posted on 2019-04-11

2048 Reading at the speed of speech: Alignment of eye-movement sampling in reading with the speech production rate

Gagl, B.; Golch, J.; Hawelka, S.; Sassenhagen, J.; Gregorova, K.; Poeppel, D.; Fiebach, C. J.

10.1101/391896 — neuroscience — Posted on 2019-04-11

2049 An efficient timer and sizer of biomacromolecular motions

Chan, J.; Lin, H.-R.; Takemura, K.; Chang, K.-C.; Chang, Y.-Y.; Joti, Y.; Kitao, A.; Yang, L.-W.

10.1101/384511 — biophysics — Posted on 2019-04-11

2050 Development of a KDM6b shRNA conditional knock down mouse model

Prier, J. E.; Blewitt, M. E.; Dickins, R. A.; Turner, S. J.

10.1101/605618 — immunology — Posted on 2019-04-11

2051 How many samples are needed to infer truly clonal mutations from heterogenous tumours?

Opasic, L.; Zhou, D.; Werner, B.; Dingly, D.; Traulsen, A.

10.1101/606053 — cancer biology — Posted on 2019-04-11

2052 An Integrative Approach for Fine-Mapping Chromatin Interactions

Jaroszewicz, A. T.; Ernst, J.

10.1101/605576 — bioinformatics — Posted on 2019-04-11

2053 Measuring the impact of an interdisciplinary learning project on nursing, architecture and landscape design students empathy

Donnelly, S.; Dean, S.; Razavy, S.; Levett-Jones, T.

10.1101/605097 — scientific communication and education — Posted on 2019-04-11

2054 A Two-Component System that Modulates Cyclic-di-GMP Metabolism Promotes Legionella pneumophila Differentiation and Viability in Low-Nutrient Conditions

Hughes, E.; Bryne, B. G.; Swanson, M. S.

10.1101/604611 — microbiology — Posted on 2019-04-11

2055 Chemical biofilm dislodgement with chelating and reducing agents in comparison to sonication: implications for the diagnosis of implant associated infection

Karbysheva, S.; Butini, M. E.; Di Luca, M.; Winkler, T.; Schuetz, M.; Trampuz, A.

10.1101/604637 — microbiology — Posted on 2019-04-11

2056 Multiple Long-read Sequencing Survey of Herpes Simplex Virus Lytic Transcriptome

Tombacz, D.; Balazs, Z.; Gulyas, G.; Csabai, Z.; Boldogkoi, M.; Snyder, M.; Boldogkoi, Z.

10.1101/605956 — genomics — Posted on 2019-04-11

2057 Comparative palatability of orally disintegrating tablets (ODTs) of Praziquantel (L-PZQ and Rac-PZQ) versus current PZQ tablet in African children: a randomized, single-blind, crossover study

MAHENDE, M. K.; Huber, E.; Kourany-Lefoll, E.; Ali, A.; Hayward, B.; Bezuidenhout, D.; Bagchus, W.; Kabanywanyi, A. M.

10.1101/605170 — epidemiology — Posted on 2019-04-11

2058 Empirical Analyses of Associations between State Political Attitudes and Gains in Health Insurance Coverage after the Affordable Care Act (ACA)

Joseph, R.; Sen, B.

10.1101/605022 — ecology — Posted on 2019-04-11

2059 EpiGraph: an open-source platform to quantify epithelial organization

Vicente-Munuera, P.; Gomez-Galvez, P. J.; Tetley, R. J.; Forja, C.; Tagua, A.; Letran, M.; Tozluoglu, M.; Mao, Y.; Escudero, L. M.

10.1101/217521 — developmental biology — Posted on 2019-04-11

2060 Multimodal transcriptional control of pattern formation in embryonic development

Lammers, N. C.; Galstyan, V.; Reimer, A.; Medin, S. A.; Wiggins, C. H.; Garcia, H. G.

10.1101/335919 — developmental biology — Posted on 2019-04-11

2061 Multi-scale deep tensor factorization learns a latent representation of the human epigenome

Schreiber, J.; Durham, T. J.; Bilmes, J.; Noble, W. S.

10.1101/364976 — bioinformatics — Posted on 2019-04-11

2062 Mesolimbic dopamine projections mediate cue-motivated reward seeking but not reward retrieval

Halbout, B.; Marshall, A. T.; Azimi, A.; Liljeholm, M.; Mahler, S. V.; Wassum, K. M.; Ostlund, S. B.

10.1101/272963 — neuroscience — Posted on 2019-04-11

2063 Testing ecological hypotheses at the pondscape with environmental DNA metabarcoding: a case study on a threatened amphibian

Harper, L. R.; Lawson Handley, L.; Hahn, C.; Boonham, N.; Rees, H. C.; Lewis, E.; Adams, I. P.; Brotherton, P.; Phillips, S.; Hänfling, B.

10.1101/278309 — ecology — Posted on 2019-04-11

2064 Sex makes them sleepy: change in host reproductive status induces diapause in a parasitoid population experiencing harsh winters

Tougeron, K.; Brodeur, J.; van Baaren, J.; Renault, D.; Le Lann, C.

10.1101/371385 — ecology — Posted on 2019-04-11

2065 ASPEN: A methodology for reconstructing protein evolutionwith improved accuracy using ensemble models

Sloutsky, R.; Naegle, K. M.

10.1101/170787 — bioinformatics — Posted on 2019-04-11

2066 Linking the chemistry and reactivity of dissolved organic matter from glaciers and rock glaciers

Fegel, T.; Boot, C.; Broeckling, C.; Hall, E.

10.1101/115808 — ecology — Posted on 2019-04-11

2067 ORF Capture-Seq: a versatile method for targeted identification of full-length isoforms

Sheynkman, G. M.; Tuttle, K. S.; Tseng, E.; Underwood, J. G.; Yu, L.; Dong, D.; Smith, M. L.; Sebra, R.; Hao, T.; Calderwood, M. A.; Hill, D. E.; Vidal, M.

10.1101/604157 — genomics — Posted on 2019-04-11

2068 Re-configuration of Chromatin Structure During the Mitosis-G1 Phase Transition

Zhang, H.; Emerson, D.; Gilgenast, T.; Titus, K.; Lan, Y.; Huang, P.; Zhang, D.; Wang, H.; Keller, C.; Giardine, B.; Hardison, R.; Phillips-Cremins, J.; Blobel, G.

10.1101/604355 — genomics — Posted on 2019-04-11

2069 Can hot temperatures limit disease transmission? A test of mechanisms in a zooplankton-fungus system

Shocket, M.; Magnante, A.; Duffy, M.; Caceres, C.; Hall, S.

10.1101/605477 — ecology — Posted on 2019-04-10

2070 A reference map of the human protein interactome

Luck, K.; Kim, D. K.; Lambourne, L.; Spirohn, K.; Begg, B. E.; Bian, W.; Brignall, R.; Cafarelli, T.; Campos-Laborie, F. J.; Charloteaux, B.; Choi, D.; Cote, A. G.; Daley, M.; Deimling, S.; Desbuleux, A.; Dricot, A.; Gebbia, M.; Hardy, M. F.; Kishore, N.; Knapp, J. J.; Kovacs, I. A.; Lemmens, I.; Mee, M. W.; Mellor, J. C.; Pollis, C.; Pons, C.; Richardson, A. D.; Schlabach, S.; Teeking, B.; Yadav, A.; Babor, M.; Balcha, D.; Basha, O.; Chin, S.-F.; Choi, S. G.; Colabella, C.; Coppin, G.; D'Amata, C.; De Ridder, D.; De Rouck, S.; Duran-Frigola, M.; Ennajdaoui, H.; Goebels, F.; Gopal, A.; Haddad

10.1101/605451 — systems biology — Posted on 2019-04-10

2071 Identification and Characterization of the First Fragment Hits for SETDB1 Tudor Domain

Mader, P.; Mendoza-Sanchez, R.; Iqbal, A.; Dong, A.; Dobrovetsky, E.; Corless, V.; Liew, S.; Houliston, S.; Ferreira De Freitas, R.; Smil, D.; Dela Sena, C.; Kennedy, S.; Diaz, D.; Wu, H.; Dombrovski, L.; Allali-Hassani, A.; Min, J.; Schapira, M.; Vedadi, M.; Brown, P.; Santhakumar, V.; Yudin, A.; Arrowsmith, C.

10.1101/605303 — pharmacology and toxicology — Posted on 2019-04-10

2072 Human Aging DNA Methylation Signatures are Conserved but Accelerated in Cultured Fibroblasts

Sturm, G.; Cardenas, A.; Bind, M.-A.; Horvath, S.; Wang, S.; Wang, Y.; Hagg, S.; Hirano, M.; Picard, M.

10.1101/605295 — cell biology — Posted on 2019-04-10

2073 Divergence from conserved residues underlies intracellular retention of mammalian odorant receptors

Ikegami, K.; de March, C. A.; Nagai, M.; Ghosh, S.; Do, M.; Sharma, R.; Bruguera, E.; Lu, Y.; Fukutani, Y.; Vaidehi, N.; Yohda, M.; Matsunami, H.

10.1101/605337 — cell biology — Posted on 2019-04-10

2074 CNTNAP2 ectodomain, detected in neuronal and CSF sheddomes, modulates Ca2+ dynamics and network synchrony

Martin-de-Saavedra, M. D.; do Santos, M.; Varea, O.; Spielman, B. P.; Gao, R.; Forrest, M.; Myczek, K.; Khalatyan, N.; Hall, E. A.; Sanz-Clemente, A.; Comoletti, D.; Lichtenthaler, S. F.; Savas, J. N.; Penzes, P.

10.1101/605378 — neuroscience — Posted on 2019-04-10

2075 Spatio-temporal analysis of human preimplantation development reveals dynamics of epiblast and trophectoderm

Meistermann, D.; Loubersac, S.; Reigner, A.; Firmin, J.; Francois - - Campion, V.; Kilens, S.; Lelievre, Y.; Lammers, J.; Feyeux, M.; Hulin, P.; Nedellec, S.; Bretin, B.; Covin, S.; Castel, G.; Bihouee, A.; Soumillon, M.; Mikkelsen, T.; Barriere, P.; Bourdon, J.; Freour, T.; David, L.

10.1101/604751 — cell biology — Posted on 2019-04-10

2076 RhoA mediates epithelial cell shape changes via mechanosensitive endocytosis

Cavanaugh, K. E.; Staddon, M. F.; Munro, E.; Banerjee, S.; Gardel, M. L.

10.1101/605485 — cell biology — Posted on 2019-04-10

2077 Body composition and markers of cardiometabolic health in transgender youth compared to cisgender youth: a cross-sectional study

Nokoff, N. J.; Scarbro, S.; Moreau, K. L.; Zeitler, P.; Nadeau, K. J.; Juarez-Colunga, E.; Kelsey, M. M.

10.1101/603019 — physiology — Posted on 2019-04-10

2078 Largest Complete Mitochondrial Genome of a Gymnosperm, Sitka Spruce (Picea sitchensis), Indicates Complex Physical Structure

Jackman, S. D.; Coombe, L.; Warren, R. L.; Kirk, H.; Trinh, E.; McLeod, T.; Pleasance, S.; Pandoh, P.; Zhao, Y.; Coope, R. J.; Bousquet, J.; Bohlmann, J.; Jones, S.; Birol, I.

10.1101/601104 — genomics — Posted on 2019-04-10

2079 Pan-genome analysis reveals the molecular basis of niche adaptation of Staphylococcus epidermidis strains

Su, F.; Tian, R.; Yang, Y.; Xu, X.; Chen, D.; Zhang, J.; Chen, X.; Zhao, G.; Xiao, F.; Li, Y.; Xu, H.

10.1101/604629 — microbiology — Posted on 2019-04-10

2080 Start from Scratch: Precisely Identify Massive Active Enhancers by Sequencing

Zhu, X.; Huang, L.; Li, Q.; Zhang, Y.

10.1101/604686 — genomics — Posted on 2019-04-10

2081 Novel lead compounds that target the ribosomal peptidyl transferase center

Tam, B.; Cohen, S.; Sherf, D.; Eisdorfer, S. A.; Perez, M.; Soffer, A.; Vilenchik, D.; Wagner, G.; Akabayov, B.

10.1101/604777 — biochemistry — Posted on 2019-04-10

2082 Dynamic adaptations in the echolocation behavior of bats in response to acoustic interference

Beetz, M. J.; Kossl, M.; Hechavarria, J. C.

10.1101/604603 — animal behavior and cognition — Posted on 2019-04-10

2083 Nitrogen Availability Modulates the Host Control of the Barley Rhizosphere Microbiota.

Alegria Terrazas, R.; Pietrangelo, L.; Corral, A. M.; Torres-Cortes, G.; Robertson-Albertyn, S.; Balbirnie-Cumming, K.; Morris, J.; Hedley, P. E.; Barret, M.; Paterson, E.; Baggs, L. M.; Bulgarelli, D.

10.1101/605204 — plant biology — Posted on 2019-04-10

2084 A new approach to crop model calibration: phenotyping plus post-processing.

Casadebaig, P.; Debaeke, P.; Wallach, D.

10.1101/605220 — plant biology — Posted on 2019-04-10

2085 Behavioral flexibility is associated with changes in structure and function distributed across a frontal cortical network in macaques

Sallet, J.; Noonan, M.; Thomas, A.; O'Reilly, J. X.; Anderson, J.; Papageorgiou, G. K.; Neubert, F. X.; Ahmed, B.; Smith, J.; Bell, A.; Buckley, M.; Roumazeilles, L.; Cuell, S.; Walton, M.; Krug, K.; Mars, R.; Rushworth, M.

10.1101/603530 — neuroscience — Posted on 2019-04-10

2086 Comparing within- and between-family polygenic score prediction

Selzam, S.; Ritchie, S. J.; Pingault, J.-B.; Reynolds, C. A.; O'Reilly, P. F.; Plomin, R.

10.1101/605006 — genomics — Posted on 2019-04-10

2087 Sox1a mediates the ability of the parapineal to impart habenular left-right asymmetry

Lekk, I.; Duboc, V.; Faro, A.; Nicolaou, S.; Blader, P.; Wilson, S. W.

10.1101/604330 — developmental biology — Posted on 2019-04-10

2088 The hypoxic ventilatory response is facilitated by the activation of Lkb1-AMPK signalling pathways downstream of the carotid bodies

Evans, A. M.; Mahmoud, A. D.; Holmes, A.; MacMillan, S.; Ogunbayo, O.; Wyatt, C. N.; Kumar, P.; Dallas, M.; Viollet, B.; Foretz, M.

10.1101/604900 — physiology — Posted on 2019-04-10

2089 Pharmacological inhibition of soluble epoxide hydrolase as a new therapy for Alzheimer’s Disease

Grinyan-Ferre, C.; Codony, S.; Pujol, E.; Yang, J.; Leiva, R.; Escolano, C.; Puigoriol-Illamola, D.; Companys-Alemany, J.; Corpas, R.; Sanfeliu, C.; Loza, M. I.; Brea, J. M.; Morisseau, C.; Hammock, B. D.; Vazquez, S.; Pallas, M.; Galdeano, C.

10.1101/605055 — pharmacology and toxicology — Posted on 2019-04-10

2090 Sustained visual priming effects can emerge from attentional oscillation and temporal expectation

Wang, M.; Huang, Y.; Luo, H.; Zhang, H.

10.1101/604702 — neuroscience — Posted on 2019-04-10

2091 The budding yeast heterochromatic SIR complex resets upon exit from stationary phase

Galic, H.; Vasseur, P.; Radman-Livaja, M.

10.1101/603613 — molecular biology — Posted on 2019-04-10

2092 Endophytic Virome

Das, S.; Barooah, M.; Thakur, N.

10.1101/602144 — microbiology — Posted on 2019-04-10

2093 Positional dynamics and glycosomal recruitment of developmental regulators during trypanosome differentiation

Szoor, B.; Simon, D.; Rojas, F.; Young, J.; Robinson, D. R.; Kruger, T.; Engstler, M.; Matthews, K. R.

10.1101/603258 — microbiology — Posted on 2019-04-10

2094 Antibiotics select for novel pathways of resistance in biofilms

Trampari, E.; Holden, E. R.; Wickham, G. J.; Ravi, A.; Prischi, F.; De-Oliviera-Martins, L.; Savva, G. M.; Bavro, V. N.; Webber, M.

10.1101/605212 — microbiology — Posted on 2019-04-10

2095 Microbial community dynamics and coexistence in a sulfide-driven phototrophic bloom

Bhatnagar, S.; Cowley, E. S.; Kopf, S. H.; Perez Castro, S.; Kearney, S.; Dawson, S.; Hanselmann, K.; Ruff, S. E.

10.1101/604504 — microbiology — Posted on 2019-04-10

2096 A Proteomic Atlas of Senescence-Associated Secretomes for Aging Biomarker Development

Basisty, N.; Kale, A.; Jeon, O.; Kuehnemann, C.; Payne, T.; Rao, C.; Holtz, A.; Shah, S.; Ferrucci, L.; Campisi, J.; Schilling, B.

10.1101/604306 — cell biology — Posted on 2019-04-10

2097 Structural excavation of cryptic sites in proteins using glycol decoys: implications in drug-design

Bansia, H.; Mahanta, P.; Ramakumar, S.

10.1101/605121 — biophysics — Posted on 2019-04-10

2098 Controlling Cell-Free Gene Expression Behavior by Tuning Membrane Transport Properties

Caveney, P. M.; Dabbs, R. M.; McClintic, W. T.; Norred, S. E.; Collier, C. P.; Simpson, M. L.

10.1101/604454 — biophysics — Posted on 2019-04-10

2099 Magnetic Resonance Fingerprinting with Combined Gradient- and Spin-echo Echo-planar Imaging: Simultaneous Estimation of T1, T2 and T2* with integrated-B1 Correction

Khajehim, M.; Christen, T.; Chen, J. J.

10.1101/604546 — biophysics — Posted on 2019-04-10

2100 Urine proteome changes in rats with approximately ten tumor cells subcutaneous inoculation.

Wei, J.; Meng, W.; Gao, Y.

10.1101/604520 — biochemistry — Posted on 2019-04-10

2101 Local parasite pressures and host genotype may modulate epigenetic diversity in a mixed-mating fish

Berbel-Filho, W. M.; Garcia de Leaniz, C.; Moran, P.; Cable, J.; Lima, S. M. Q.; Consuegra, S.

10.1101/603274 — zoology — Posted on 2019-04-10

2102 Yeast Sup35 prion structure: two types, four parts, many variants

Dergalev, A. A.; Alexandrov, A. I.; Ivannikov, R. I.; Ter-Avanesyan, M. D.; Kushnirov, V. V.

10.1101/604660 — molecular biology — Posted on 2019-04-10

2103 Fecal short-chain fatty acids are not predictive of colonic tumor status and cannot be predicted based on bacterial community structure

Sze, M. A.; Topcuoglu, B. D.; Lesniak, N. A.; Ruffin, M. T.; Schloss, P. D.

10.1101/604678 — microbiology — Posted on 2019-04-10

2104 Genomic Analysis of Emerging Florfenicol-Resistant Campylobacter coli Isolated from the Intestinal Cecal Contents of Cattle in the United States

Zhao, S.; Mukherjee, S.; Hsu, C.-H.; Young, S.; Li, C.; Tate, H.; Morales, C.; Haro, J.; Thitaram, S.; Tillman, G.; Dessai, U.; McDermott, P. F.

10.1101/604645 — microbiology — Posted on 2019-04-10

2105 Integrated phylogenomic analyses reveal recurrent ancestral large-scale duplication events in mosses

Gao, B.; Chen, M.; Li, X.; Liang, Y.; Zhang, D.; Wood, A.; Oliver, M.; Zhang, J.

10.1101/603191 — evolutionary biology — Posted on 2019-04-10

2106 Social information drives ecological outcomes among competing species

Gil, M. A.; Baskett, M. L.; Schreiber, S.

10.1101/604595 — ecology — Posted on 2019-04-10

2107 Endogenous TDP-43 prevents retrotransposons activation through Dicer-2 activity and the RNA silencing machinery in Drosophila

Feiguin, F.; Romano, G.; Klima, R.

10.1101/604421 — cell biology — Posted on 2019-04-10

2108 AGO1x prevents dsRNA-induced interferon signaling to promote breast cancer cell proliferation

Ghosh, S.; Guimaraes, J.; Lanzafame, M.; Schmidt, A.; Syed, A.; Dimitriades, B.; Boersch, A.; Ghosh, S.; Correia, A.; Danner, J.; Meister, G.; Terracciano, L.; Piscuoglio, S.; Zavolan, M.

10.1101/603506 — cell biology — Posted on 2019-04-10

2109 tagPAINT: Stoichiometric and covalent labelling of protein tags for multiplexed and quantitative DNA-PAINT imaging

Nieves, D. J.; Hilzenrat, G.; Tran, J.; Yang, Z.; MacRae, H. H.; Baker, M. A. B.; Gooding, J. J.; Gaus, K.

10.1101/604462 — biophysics — Posted on 2019-04-10

2110 Coheritability and Coenvironmentability as Concepts for Partitioning the Phenotypic Correlation

Vasquez-Kool, J.

10.1101/598623 — genetics — Posted on 2019-04-10

2111 CRISPR/Cas9 Treatment Causes Extended TP53-Dependent Cell Cycle Arrest In Human Cells

Geisinger, J. M.; Stearns, T.

10.1101/604538 — genetics — Posted on 2019-04-10

2112 Agreement between two large pan-cancer CRISPR-Cas9 gene dependency datasets

10.1101/604447 — cancer biology — Posted on 2019-04-10

2113 A network-based data-mining approach to investigate indole-related microbiota-host co-metabolism

Neves, A. L.; Rodriguez-Martinez, A.; Ayala, R.; Posma, J. M.; U, M. A.; Chilloux, J.; Nicholson, J. K.; Dumas, M.-E.; Hoyles, L.

10.1101/602458 — bioinformatics — Posted on 2019-04-10

2114 Thermal ecology of malaria transmission and the potential impact of behavioural resistance

Suh, E.; Grossman, M. K.; Waite, J. L.; Sherrard-Smith, E.; Churcher, T. S.; Thomas, M. B.

10.1101/604249 — ecology — Posted on 2019-04-10

2115 WASP restricts active Rac to maintain cells’ front-rear polarisation

Amato, C.; Thomason, P. A.; Davidson, A. J.; Swaminathan, K.; Ismail, S.; Machesky, L. M.; Insall, R. H.

10.1101/602425 — cell biology — Posted on 2019-04-10

2116 Malachite: A Gene Enrichment Meta-Analysis (GEM) Tool for ToppGene

Gershkowitz, G. R.; Abrams, Z. B.; Coombes, C. E.; Coombes, K.

10.1101/511527 — bioinformatics — Posted on 2019-04-10

2117 The Cupin Protein, Dehydratase Pac13 is a Homodimer

ZHANG, R.

10.1101/600247 — biochemistry — Posted on 2019-04-10

2118 Growth and selection of the cyanobacterium Synechococcus sp. PCC 7002 using alternative nitrogen and phosphorus sources

Selao, T. T.; Włodarczyk, A.; Nixon, P. J.; Norling, B.

10.1101/603373 — synthetic biology — Posted on 2019-04-10

2119 Neurophysiological correlates of collective perceptual decision-making

Baumgart, K. G.; Byvshev, P.; Sliby, A.-N.; Strube, A.; König, P.; Wahn, B.

10.1101/601674 — neuroscience — Posted on 2019-04-10

2120 Stimulation of cardiac fibroblast Piezo1 channels opposes myofibroblast differentiation and induces IL-6 secretion via Ca2+-mediated p38 MAP kinase activation

Blythe, N. M.; Stylianidis, V.; Ludlow, M. J.; Gilbert, H. T.; Evans, E. L.; Cuthbertson, K.; Foster, R.; Swift, J.; Li, J.; Drinkhill, M. J.; van Nieuwenhoven, F. A.; Porter, K. E.; Beech, D. J.; Turner, N. A.

10.1101/603456 — cell biology — Posted on 2019-04-10

2121 New logic facilitated identification of novel phage recombinase function units

Chang, Y.; Wang, Q.; Su, T.; Qi, Q.

10.1101/598011 — bioinformatics — Posted on 2019-04-10

2122 Dynamic changes in the urine proteome in two ovarian cancer rat models

Li, Y.; Zhang, L.; Meng, W.; Gao, Y.

10.1101/604850 — biochemistry — Posted on 2019-04-10

2123 Pentamycin biosynthesis in Philippine Streptomyces sp. S816: Cytochrome P450-catalysed installation of the C-14 hydroxyl group

Zhou, S.; Song, L.; Masschelein, J.; Sumang, F. A.; Papa, I. A.; Zulaybar, T. O.; Custodio, A. B.; Zabala, D.; Alcantara, E. P.; de los Santos, E. L.; Challis, G. L.

10.1101/604736 — biochemistry — Posted on 2019-04-10

2124 Intraspecific variation in Artiodactyla social organisation: A Bayesian phylogenetic multilevel analysis of detailed population-level data

Miles, M. I.; Jaeggi, A. V.; Festa-Bianchet, M.; Schradin, C.; Hayes, L. D.

10.1101/603399 — animal behavior and cognition — Posted on 2019-04-10

2125 High fat diet induces a microbiota-dependent increase in stem cell activity in the Drosophila intestine

von Frieling, J.; Faisal, M. M.; Sporn, F.; Pfefferkorn, R.; Sommer, F.; Rosenstiel, P.; Roeder, T.

10.1101/604744 — physiology — Posted on 2019-04-10

2126 Home, head direction stability and grid cell distortion

Sanguinett-Scheck, J. I.; Brecht, M.

10.1101/602771 — neuroscience — Posted on 2019-04-10

2127 Vulnerable species interactions are important for the stability of mutualistic networks

Simmons, B. I.; Wauchope, H. S.; Amano, T.; Dicks, L. V.; Sutherland, W. J.; Dakos, V.

10.1101/604868 — ecology — Posted on 2019-04-10

2128 Human mitochondrial variant annotation with HmtNote

Preste, R.; Clima, R.; Attimonelli, M.

10.1101/600619 — bioinformatics — Posted on 2019-04-10

2129 Modeling unitary fields and the single neuron contribution to local field potentials in the hippocampus

Telenczuk, M.; Telenczuk, B.; Destexhe, A.

10.1101/602953 — neuroscience — Posted on 2019-04-10

2130 Simulation of model overfit in variance explained with genetic data

Derringer, J.

10.1101/598904 — genetics — Posted on 2019-04-10

2131 ATM and ATR Influence Meiotic Crossover Formation Through Antagonistic and Overlapping Functions in C. elegans

Yanowitz, J. L.; Li, W.

10.1101/604827 — genetics — Posted on 2019-04-10

2132 Emergence of Novel Lineage of Foot-and-Mouth Disease Virus Serotype Asia1 BD-18 (G-IX) in Bangladesh

Ali, M. R.; Alam, A. S. M. R. U.; Amin, M. A.; Siddique, M. A.; Sultana, M.; Hossain, M. A.

10.1101/604892 — evolutionary biology — Posted on 2019-04-10

2133 Host developmental stage is associated with shifts in the exosphere microbiome of urban-farmed Asian green leafy vegetables

Pavagadhi, S.; Bandla, A.; Hong, M. P. C.; Umashankar, S.; Yeap, Y. T.; Swarup, S.

10.1101/604819 — systems biology — Posted on 2019-04-10

2134 The power of model-to-crop translation illustrated by reducing seed loss from pod shatter in oilseed rape

Stephenson, P.; Stacey, N.; Brueser, M.; Pullen, N.; Ilyas, M.; O'Neill, C.; Wells, R.; Ostergaard, L.

10.1101/604769 — plant biology — Posted on 2019-04-10

2135 Conservative and disruptive modes of adolescent change in brain functional connectivity

Vasa, F.; Romero-Garcia, R.; Kitzbichler, M. G.; Seidlitz, J.; Whitaker, K. J.; Vaghi, M. M.; Kundu, P.; Patel, A. X.; Fonagy, P.; Dolan, R. J.; Jones, P. B.; Goodyer, I. M.; the NSPN consortium, ; Vertes, P. E.; Bullmore, E. T.

10.1101/604843 — neuroscience — Posted on 2019-04-10

2136 A spatiotemporal ventricular myocyte model incorporating mitochondrial calcium cycling

Song, Z.; Xie, L.; Weiss, J. N.; Qu, Z.

10.1101/604926 — biophysics — Posted on 2019-04-10

2137 Diagnostic value of chest ultrasound in children with cystic fibrosis.

Strzelczuk - Judka, L.; wojsyk - banaszak, i.; Zakrzewska, A.; Jonczyk - Potoczna, K.

10.1101/604942 — scientific communication and education — Posted on 2019-04-10

2138 Pelleted-hay alfalfa feed increases sheep wether weight gain and rumen bacterial richness over loose-hay alfalfa feed.

Ishaq, S. L.; Lachman, M. M.; Wenner, B. A.; Baeza, A.; Butler, M.; Gates, E.; Olivo, S.; Geddes, J. B.; Hatfield, P.; Yeoman, C. J.

10.1101/605113 — microbiology — Posted on 2019-04-10

2139 Targeting against HIV/HCV Co-infection using Machine Learning-based multitarget-quantitative structure-activity relationships (mt-QSAR) Methods

Wei, Y.; Li, W.; Du, T.; Hong, Z.; Lin, J.

10.1101/605162 — bioinformatics — Posted on 2019-04-10

2140 Research applications of primary biodiversity databases in the digital age

Ball-Damerow, J.; Brenskelle, L.; Barve, N.; Soltis, P. S.; Sierwald, P.; Bieler, R.; LaFrance, R.; Arino, A. H.; Guralnick, R.

10.1101/605071 — zoology — Posted on 2019-04-10

2141 The level of workaholism and its relation to positive and negative perfectionism

Aldahadha, B.

10.1101/604934 — scientific communication and education — Posted on 2019-04-10

2142 Resistance to Candidatus Liberibacter solanacearum in tomato landraces from Mexico

Garzon-Tiznado, J. A.; Lopez-Orona, C. A.; Castro-Espinoza, L.; Velarde-Felix, S.; Figueroa-Perez, M. G.; Retes Manjarrez, J. E.

10.1101/605188 — plant biology — Posted on 2019-04-10

2143 Exploring the association of collaterals and vessel density using optical coherence tomography angiography in retinal vein occlusions

Fawzi, A. A.; Lee, H. E.; Wang, Y.; Fayed, A. E.

10.1101/604983 — physiology — Posted on 2019-04-10

2144 Morphogenesis of giant telomeric nuclear bodies in cancer cells with alternative lengthening of telomeres

Kamma, H.; arimasu, Y.; Fujiwara, M.; Ishii, J.; Chiba, T.; Terado, Y.; Shishido-Hara, Y.

10.1101/604959 — pathology — Posted on 2019-04-10

2145 Post-ictal neuronal network remodeling and Wnt pathway dysregulation in the intra-hippocampal kainate mouse model of temporal lobe epilepsy

Gupta, K.; Schnell, E.

10.1101/604975 — neuroscience — Posted on 2019-04-10

2146 Tracing the environmental footprint of the Burkholderia pseudomallei lipopolysaccharide genotypes in the tropical \"Top End\" of the Northern Territory, Australia

Webb, J.; Rachlin, A.; Rigas, V.; Sarovich, D. S.; Price, E. P.; Kaestli, M.; Ward, L. M.; Mayo, M.; Currie, B. J.

10.1101/603886 — molecular biology — Posted on 2019-04-10

2147 Characterization of a new cytorhabdovirus discovered in papaya (Carica papaya) plantings of Ecuador and its relationship with a bean-infecting strain from Brazil

Quito-Avila, D. F.; Medina-Salguero, A. X.; Cornejo-Franco, J. F.; Grinstead, S.; Mollov, D.; Mowery, J. D.; Flores, F.

10.1101/605139 — microbiology — Posted on 2019-04-10

2148 Tuberculosis at farmer-cattle interface in the rural villages of South Gondar Zone of northwest Ethiopia

Alelign, A.; Zewude, A.; Petros, B.; Ameni, G.

10.1101/605154 — epidemiology — Posted on 2019-04-10

2149 Mechanistic insights into the phosphoryl transfer reaction in cyclin-dependent kinase 2: a QM/MM study

Recabarren, R.; Osorio, E. H.; Caballero, J.; Tunon, I.; Alzate-Morales, J. H.

10.1101/605048 — bioinformatics — Posted on 2019-04-10

2150 Comparing infiltration rates in soils managed with conventional and alternative farming methods: a meta-analysis

Basche, A.; DeLonge, M.

10.1101/603696 — ecology — Posted on 2019-04-10

2151 Evaluating environmental and ecological landscape characteristics relevant to urban resilience across gradients of land-sharing-sparing and urbanity

Dennis, M.; Scaletta, K. L.; James, P.

10.1101/605105 — ecology — Posted on 2019-04-10

2152 Clinical evaluation of presepsin considering renal function.

Miyoshi, M.; Inoue, Y.; Nishioka, M.; Ikegame, A.; Nakao, T.; Nagai, K.

10.1101/604991 — biochemistry — Posted on 2019-04-10

2153 Genetic Susceptibility to Multiple Sclerosis: Interactions between Conserved Extended Haplotypes of the MHC and other Susceptibility Regions

Goodin, D. S.; Khankhanian, P.; Gourraud, P.-A.; Vince, N.

10.1101/603878 — epidemiology — Posted on 2019-04-10

2154 DNA barcoding reveals that injected transgenes are predominantly processed by homologous recombination in mouse zygote

Smirnov, A.; Yunusova, A.; Korablev, A.; Serova, I.; Fishman, V.; Battulin, N.

10.1101/603381 — molecular biology — Posted on 2019-04-10

2155 EM-LDDMM for 3D to 2D registration

Tward, D.; Miller, M.

10.1101/604405 — neuroscience — Posted on 2019-04-10

2156 Prevalence of Hepatitis C Virus Genotypes in the Southern Region, Saudi Arabia

Alkahtani, A. M.; Alsultan, M. N.; Hakami, A. R.; Alamri, M.

10.1101/603902 — microbiology — Posted on 2019-04-10

2157 The Parkinsons Disease Mendelian Randomization Research Portal

Noyce, A.; Bandres Ciga, S.; Kim, J.; Heilbron, K.; kia, D.; Hemani, G.; Xue, A.; Lawlor, D. A.; Davey Smith, G.; Duran, R.; Gan-Or, Z.; Blauwendraat, C.; Gibbs, R.; 23andMe, ; International Parkinson's Disease Genomics Consort, ; Hinds, D.; Yang, J.; Visscher, P. M.; Cuzick, J.; Morris, H.; Hardy, J.; Wood, N.; Nalls, M. A.; Singleton, A.

10.1101/604033 — neuroscience — Posted on 2019-04-10

2158 Generative network models identify biological mechanisms of altered structural brain connectivity in schizophrenia

Zhang, X.; Braun, U.; Harneit, A.; Zang, Z.; Geiger, L.; Betzel, R.; Chen, J.; Schweiger, J.; Schwarz, K.; Reinwald, J. R.; Fritze, S.; Witt, S.; Rietschel, M.; Noethen, M. M.; Degenhardt, F.; Schwarz, E.; Hirjak, D.; Meyer-Lindenberg, A.; Bassett, D. S.; Tost, H.

10.1101/604322 — neuroscience — Posted on 2019-04-10

2159 Comparative analysis of amplicon and metagenomic sequencing methods reveals key features in the evolution of animal metaorganisms

Rausch, P.; Rühlemann, M.; Hermes, B.; Doms, S.; Dagan, T.; Dierking, K.; Domin, H.; Fraune, S.; von Frieling, J.; Henschel Humeida, U.; Heinsen, F. A.; Höppner, M.; Jahn, M.; Jaspers, C.; Kissoyan, K. A. B.; Langfeldt, D.; Rehman, A.; Reusch, T. B.; Röder, T.; Schmitz, R. A.; Schulenburg, H.; Soluch, R.; Sommer, F.; Stukenbrock, E.; Weiland-Bräuer, N.; Rosenstiel, P.; Franke, A.; Bosch, T.; Baines, J. F.

10.1101/604314 — microbiology — Posted on 2019-04-10

2160 Focused screening reveals functional effects of microRNAs differentially expressed in colorectal cancer

Sastre, D.; Baiochi, J.; Lima, I. M. d. S.; Schiavinato, J. L. d. S.; Covas, D. T.; Panepucci, R. A.

10.1101/601484 — cancer biology — Posted on 2019-04-10

2161 RNA polymerases as moving barriers to condensin loop extrusion

Brandao, H. B.; Wang, X.; Paul, P.; van den Berg, A.; Rudner, D. Z.; Mirny, L. A.

10.1101/604280 — biophysics — Posted on 2019-04-10

2162 CENP-C stabilizes the conformation of CENP-A nucleosomes within the inner kinetochore at human centromere

Melters, D. P.; Rakshit, T.; Grigoryev, S. A.; Sturgill, D.; Dalal, Y.

10.1101/604223 — biochemistry — Posted on 2019-04-10

2163 Differential characterization of physiological and biochemical responses during drought stress in finger millet varieties

Mukami, A.; Ngetich, A.; Mweu, C.; Oduor, R.; Muthangya, M.; Mbinda, W. M.

10.1101/603944 — plant biology — Posted on 2019-04-10

2164 In the Body’s Eye: The Computational Anatomy of Interoceptive Inference

Allen, M.; Levy, A.; Parr, T.; Friston, K. J.

10.1101/603928 — neuroscience — Posted on 2019-04-10

2165 Quantitative proteomic alterations of human iPSC-based neuronal development indicate early onset of Rett syndrome.

Varderidou, S.; Hinz, l.; Hagemans, D.; Postuma, D.; Altelaar, M.; Heine, V.

10.1101/603647 — neuroscience — Posted on 2019-04-10

2166 Sampling strategy optimization to increase statistical power in landscape genomics: a simulation-based approach

Selmoni, O.; Vajana, E.; Joost, S.

10.1101/603829 — evolutionary biology — Posted on 2019-04-10

2167 Poorer auditory sensitivity is related to stronger visual enhancement of the human auditory mismatch negativity (MMNm)

Moller, C.; Hojlund, A.; Baerentsen, K. B.; Hansen, N. C.; Skewes, J. C.; Vuust, P.

10.1101/604165 — neuroscience — Posted on 2019-04-09

2168 Augmenting Quadriplegic Hand Function Using a Sensorimotor Demultiplexing Neural Interface

Ganzer, P. D.; Colachis, S. C.; Schwemmer, M. A.; Friedenberg, D. A.; Swiftney, C. E.; Jacobowitz, A. F.; Weber, D. J.; Bockbrader, M. A.; Sharma, G.

10.1101/604108 — neuroscience — Posted on 2019-04-10

2169 Evidence for a multi-level trophic organization of the human gut microbiome

Wang, T.; Goyal, A.; Dubinkina, V.; Maslov, S.

10.1101/603365 — microbiology — Posted on 2019-04-09

2170 Drosophila adult muscle precursor cells contribute to motor axon pathfinding and proper innervation of embryonic muscles

Lavergne, G.; Jagla, K.

10.1101/604215 — developmental biology — Posted on 2019-04-09

2171 Transcription amplification by nuclear speckle association

Kim, J.; Khanna, N.; Belmont, A. S.

10.1101/604298 — cell biology — Posted on 2019-04-09

2172 Tissue-specific changes in the RNA structurome mediate salinity response in Arabidopsis

Tack, D.; Su, Z.; Yu, Y.; Bevilacqua, P.; Assmann, S.

10.1101/604199 — plant biology — Posted on 2019-04-09

2173 Traces of Meaning Itself: Encoding distributional word vectors in brain activity

Sassenhagen, J.; Fiebach, C. J.

10.1101/603837 — neuroscience — Posted on 2019-04-09

2174 Altered functional interactions between neurons in primary visual cortex of macaque monkeys with experimental amblyopia

Acar, K.; Kiorpes, L.; Movshon, J. A.; Smith, M. A.

10.1101/604009 — neuroscience — Posted on 2019-04-09

2175 Multiplexed and Inducible Gene Modulation in Human Pluripotent Stem Cells by CRISPR Interference and Activation

Hazelbaker, D. Z.; Beccard, A.; Mazzucato, P.; Angelini, G.; Messana, A.; Lam, D.; Eggan, K.; Barrett, L. E.

10.1101/603951 — molecular biology — Posted on 2019-04-09

2176 Induced expression of Xerophyta viscosa XvSap1 gene greatly impacts tolerance to drought stress in transgenic sweetpotato

Mbinda, W.; Dixelius, C.; Oduor, R.; none,

10.1101/603910 — molecular biology — Posted on 2019-04-09

2177 Ornithine capture by a translating ribosome controls bacterial polyamine synthesis

Herrero del Valle, A.; Seip, B.; Cervera-Marzal, I.; Sacheau, G.; Seefeldt, A. C.; Innis, C. A.

10.1101/604074 — microbiology — Posted on 2019-04-09

2178 An ex vivo cystic fibrosis model recapitulates key clinical aspects of chronic Staphylococcus aureus infection

Sweeney, E.; Hassan, M. M.; Harrington, N. E.; Smyth, A. R.; Hurley, M. N.; Tormo-Mas, M. A.; Harrison, F.

10.1101/604363 — microbiology — Posted on 2019-04-09

2179 Bacterial DNA induces the formation of heat-resistant disease-associated \"Tetz-proteins\" in human plasma

Tetz, V.; Tetz, G.

10.1101/604090 — microbiology — Posted on 2019-04-09

2180 B cells suppress medullary granulopoiesis by an extracellular glycosylation-dependent mechanism

Irons, E. E.; Lee-Sundlov, M. M.; Hoffmeister, K. M.; Lau, J. T. Y.

10.1101/604264 — immunology — Posted on 2019-04-09

2181 Measuring and Mitigating PCR Bias in Microbiome Data

Silverman, J. D.; Bloom, R. J.; Jiang, S.; Durand, H. K.; Mukherjee, S.; David, L. A.

10.1101/604025 — genomics — Posted on 2019-04-09

2182 Chromatin co-accessibility is highly structured, spans entire chromosomes, and mediates long range regulatory genetic effects

Young Greenwald, W. W.; D'Antonio-Chronowska, A.; Benaglio, P.; Matsui, H.; Smith, E. N.; D'Antonio, M.; Frazer, K. A.

10.1101/604371 — genomics — Posted on 2019-04-09

2183 Transcriptome Surveys in Silverfish Suggest a Multistep Origin of the Insect Odorant Receptor Gene Family

Thoma, M.; Missbach, C.; Jordan, M. D.; Grosse-Wilde, E.; Newcomb, R. D.; Hansson, B. S.

10.1101/604389 — evolutionary biology — Posted on 2019-04-09

2184 Exploring the lower thermal limits for transmission of human malaria, Plasmodium falciparum

Waite, J. L.; Suh, E.; Lynch, P. A.; Thomas, M. B.

10.1101/603787 — ecology — Posted on 2019-04-09

2185 High-Throughput Single-Molecule Analysis via Divisive Segmentation and Clustering

White, D.; Goldschen-Ohm, M.; Goldsmith, R.; Chanda, B.

10.1101/603761 — biophysics — Posted on 2019-04-09

2186 Rapid Generation of Medical Countermeasure Candidates Via Computational Variation Analysis

Ricke, D. O.

10.1101/604256 — bioinformatics — Posted on 2019-04-09

2187 neoANT-HILL: an integrated tool for identification of potential neoantigens

Coelho, A. C. M. F.; Fonseca, A. L. F.; Martins, D. L.; da Cunha, L. M.; Lins, P. B.; de Souza, S. J.

10.1101/603670 — bioinformatics — Posted on 2019-04-09

2188 Revisiting G3BP-S149 phosphorylation and its impact on stress granule assembly

Panas, M. D.; Kedersha, N.; Schulte, T.; Branca, R. M.; Ivanov, P.; Anderson, P. J.

10.1101/598201 — cell biology — Posted on 2019-04-09

2189 Focal adhesion kinase confers pro-migratory and anti apoptotic properties and is a potential therapeutic target in Ewing sarcoma

Steinestel, K.; Jansen, E.-P.; Trautmann, M.; Dirksen, U.; Rehkaemper, J.; Mikesch, J.-H.; Gerke, J. S.; Orth, M. F.; Sannino, G.; Wardelmann, E.; Gruenewald, T. G. P.; Hartmann, W.

10.1101/604207 — cancer biology — Posted on 2019-04-09

2190 Crowder-induced Conformational Ensemble Shift in Escherichia Coli Prolyl-tRNA Synthetase

Adams, L. M.; Andrews, R. J.; Hu, Q. H.; Schmit, H. L.; Hati, S.; Bhattacharyay, S.

10.1101/603548 — biophysics — Posted on 2019-04-09

2191 Co-culture of Saccharomyces cerevisiae (VS3) and Pichia stipitis (NCIM 3498) for bioethanol production using concentrated Prosopis juliflora acid hydrolysate

Naseeruddin, S.; Desai, S.; L, V. R.

10.1101/601278 — bioengineering — Posted on 2019-04-09

2192 Model-averaged regression coefficients have a straightforward interpretation using causal conditioning

Walker, J. A.

10.1101/133785 — ecology — Posted on 2019-04-09

2193 Flexible connectivity under physiological constraints.

Ocker, G. K.; Buice, M. A.

10.1101/603027 — neuroscience — Posted on 2019-04-09

2194 Single-molecule analysis reveals the rapid effect of estradiol on the surface movement of AMPAR in live neurons

Godo, S.; Barabas, K.; Lengyel, F.; Ernszt, D.; Kovacs, T.; Kecskes, M.; Varga, C.; Janosi, T. Z.; Barbara, O.; Kovacs, G.; Fujiwara, T.; Kusumi, A.; Abraham, I. M.

10.1101/602813 — neuroscience — Posted on 2019-04-09

2195 Nuclear gene transformation in a dinoflagellate

Sprecher, B. N.; Zhang, H.; Lin, S.

10.1101/602821 — molecular biology — Posted on 2019-04-09

2196 Putative cis-regulatory elements predict iron deficiency responses in Arabidopsis roots

Schwarz, B.; Azodi, C. B.; Shiu, S.-H.; Bauer, P.

10.1101/603290 — plant biology — Posted on 2019-04-09

2197 Recovery of Information from Latent Memory Stores Decreases Over Time.

Nouri, A.; Ester, E.

10.1101/537076 — neuroscience — Posted on 2019-04-09

2198 Impact of physico-chemical parameters on the denitrification and the co-occurrence of Methylophaga nitratireducenticrescens and Hyphomicrobium nitrativorans in a methanol-fed marine denitrifying biofilm

Payette, G.; Geoffroy, V.; Martineau, C.; Villemur, R.

10.1101/602896 — microbiology — Posted on 2019-04-09

2199 Conserved DNA polymorphisms distinguish species in the eastern North American white oak syngameon: Insights from an 80-SNP oak DNA genotyping toolkit

Hipp, A. L.; Whittemore, A. T.; Garner, M.; Hahn, M.; Fitzek, E.; Guichoux, E.; Cavender-Bares, J.; Gugger, P. F.; Manos, P. S.; Pearse, I. S.; Cannon, C. H.

10.1101/602573 — evolutionary biology — Posted on 2019-04-09

2200 Phylodynamic and Evolutionary analysis of Rotavirus G12 in Africa

Motayo, B. O.; Oluwasemowo, O. O.; Olusola, B. A.; Opayele, A.; Faneye, A. O.

10.1101/591297 — epidemiology — Posted on 2019-04-09

2201 Transmission of West Nile virus and other temperate mosquito-borne viruses occurs at lower environmental temperatures than tropical diseases

Shocket, M. S.; Verwillow, A. B.; Numazu, M. G.; Slamani, H.; Cohen, J. M.; El Moustaid, F.; Rohr, J. R.; Johnson, L. R.; Mordecai, E. A.

10.1101/597898 — ecology — Posted on 2019-04-09

2202 Suction feeding performance and prey escape response interact to determine feeding success in larval fish

Sommerfeld, N.; Holzman, R.

10.1101/603316 — zoology — Posted on 2019-04-09

2203 A passive, camera-based head-tracking system for real-time, 3D estimate of head position and orientation in rodents

Vanzella, W.; Grion, N.; Bertolini, D.; Perissinotto, A.; Zoccolan, D.

10.1101/599365 — neuroscience — Posted on 2019-04-09

2204 High angular resolution diffusion MRI reveals conserved and deviant programs in the paths that guide human cortical circuitry

Charvet, C. J.; Das, A.; Song, J. W.; Tindal-Burgess, D. J.; Kabaria, P.; Dai, G.; Kane, T.; Takahashi, E.

10.1101/576967 — neuroscience — Posted on 2019-04-09

2205 Timing is (almost) everything in a comprehensive, spike-resolved flight motor program

Conn, R.; Putney, J.; Sponberg, S.

10.1101/602961 — neuroscience — Posted on 2019-04-09

2206 Alzheimer’s disease clinical variants show distinct regional patterns of neurofibrillary tangle accumulation

Petersen, C.; Nolan, A. L.; Resende, E. d. P. F.; Miller, Z.; Ehrenberg, A. J.; Gorno-Tempini, M. L.; Rosen, H. J.; Kramer, J. H.; Spina, S.; Rabinovici, G. D.; Miller, B. L.; Seeley, W.; Miller, Z.; Heinsen, H.; Grinberg, L.

10.1101/538496 — pathology — Posted on 2019-04-09

2207 What, if anything, is the true neurophysiological significance of rotational dynamics?

Lebedev, M. A.; Adell Mill, N.; Armengol Urpi, N.; Cervera, M. R.; Nicolelis, M. A.

10.1101/597419 — neuroscience — Posted on 2019-04-09

2208 Rapid Time-stamped Analysis of Filament Motility

Ijpma, G.; Balassy, Z.; Lauzon, A.-M.

10.1101/399006 — molecular biology — Posted on 2019-04-09

2209 First report of reference guided genome assembly of Black Bengal goat (Capra hircus)

Siddiki, A. Z.; Baten, A.; Billah, M.; Alam, M. A. U.; Shawrob, K. S. M.; Saha, S.; Chowdhury, M.; Rahman, A. H.; Stear, M.; Miah, G.; Kumkum, M.; Hossain, M. A.; Islam, M. S.; Khan, M. K. I.

10.1101/603266 — genomics — Posted on 2019-04-09

2210 Joint species distribution modelling with HMSC-R

Tikhonov, G.; Opedal, O.; Abrego, N.; Lehikoinen, A.; Ovaskainen, O.

10.1101/603217 — ecology — Posted on 2019-04-09

2211 Virtual Microbes evolve multiple mechanisms to the same end: anticipating a serial transfer protocol

van Dijk, B.; Meijer, J.; Cuypers, T. D.; Hogeweg, P.

10.1101/554766 — evolutionary biology — Posted on 2019-04-09

2212 Global distribution of earthworm diversity

Phillips, H. R. P.; Guerra, C. A.; Bartz, M. L. C.; Briones, M. J. I.; Brown, G.; Ferlian, O.; Gongalsky, K. B.; Krebs, J.; Orgiazzi, A.; Schwarz, B.; Bach, E. M.; Bennett, J.; Brose, U.; Decaëns, T.; De Vries, F. T.; König-Ries, B.; Loreau, M.; Mathieu, J.; Mulder, C.; van der Putten, W.; Ramirez, K. S.; Rillig, M. C.; Russell, D.; Rutgers, M.; Thakur, M. P.; Wall, D.; Wardle, D.; sWorm Data Providers, ; Cameron, E. K.; Eisenhauer, N.

10.1101/587394 — ecology — Posted on 2019-04-09

2213 Improved bacteria population structure analysis on thousands of genomes using unsupervised methods

Schlum, K. A.; Jun, S.-R.; Udaondo, Z.; Ussery, D. W.; Emrich, S. J.

10.1101/599944 — bioinformatics — Posted on 2019-04-09

2214 Completing missing MeSH code mappings in UMLS through alternative expert-curated sources

Garcia del Valle, E. P.; Lagunes Garcia, G.; Prieto Santamaria, L.; Zanin, M.; Rodriguez Gonzalez, A.; Menasalvas, E.

10.1101/602540 — bioinformatics — Posted on 2019-04-09

2215 Predicting synchronous firing of large neural populations from sequential recordings

Sorochynskyi, O.; Deny, S.; Marre, O.; Ferrari, U.

10.1101/560656 — neuroscience — Posted on 2019-04-09

2216 Towards HCP-Style Macaque Connectomes: 24-Channel 3T Multi-Array Coil, MRI Sequences and Preprocessing

Autio, J. A.; Glasser, M. F.; Ose, T.; Donahue, C. J.; Bastiani, M.; Ohno, M.; Kawabata, Y.; Urushibata, Y.; Murata, K.; Nishigori, K.; Yamaguchi, M.; Hori, Y.; Yoshida, A.; Go, Y.; Coalson, T. S.; Jbabdi, S.; Sotiropoulos, S. N.; Smith, S.; Van Essen, D. C.; Hayashi, T.

10.1101/602979 — neuroscience — Posted on 2019-04-09

2217 Multi-disease associated risk locus in IL6 represses the anti-inflammatory gene GPNMB through chromatin looping and recruiting MEF2-HDAC complex

Kong, X.; Sawalha, A. H.

10.1101/602797 — genetics — Posted on 2019-04-09

2218 Greater loss of female embryos during human pregnancy: A novel mechanism.

Mulley, J. F.

10.1101/418186 — developmental biology — Posted on 2019-04-09

2219 Multi-stage models for the failure of complex systems, cascading disasters, and the onset of disease

Webster, A. J.

10.1101/476242 — cancer biology — Posted on 2019-04-09

2220 Developing and Evaluating Mappings of ICD-10 and ICD-10-CM Codes to PheCodes

Wu, P.; Gifford, A.; Meng, X.; Li, X.; Campbell, H.; Varley, T.; Zhao, J.; Carroll, R.; Bastarache, L.; Denny, J. C.; Theodoratou, E.; Wei, W.-Q.

10.1101/462077 — bioinformatics — Posted on 2019-04-09

2221 Fidelity of Prespacer Capture and Processing is Governed by the PAM Mediated Interaction of Cas1-2 Adaptation complex in Escherichia coli

Yoganand, K. N. R.; Muralidharan, M.; Anand, B.

10.1101/602623 — biochemistry — Posted on 2019-04-09

2222 Evaluating the quorum quenching potential of bacteria associated to Aurelia aurita and Mnemiopsis leidyi

Prasse, D.; Weiland-Braeuer, N.; Jaspers, C.; Reusch, T. B. H.; Schmitz-Streit, R. A.

10.1101/602268 — microbiology — Posted on 2019-04-09

2223 Harnessing the Anti-Cancer Natural Product Nimbolide for Targeted Protein Degradation

Spradlin, J. N.; Hu, X.; Ward, C. C.; Brittain, S. M.; Jones, M. D.; Ou, L.; To, M.; Proudfoot, A.; Ornleas, E.; Woldegiorgis, M.; Olzmann, J. A.; Bussiere, D. E.; Thomas, J. R.; Tallarico, J. A.; McKenna, J. M.; Schirle, M.; Maimone, T. J.; Nomura, D. K.

10.1101/436998 — cancer biology — Posted on 2019-04-09

2224 Identification of target candidate in Polycystic ovarian syndrome and in vitro evaluation of therapeutic activity of the designed RNA Aptamer

Manibalan, S.

10.1101/603357 — systems biology — Posted on 2019-04-09

2225 Nuisance effects in inter-scan functional connectivity estimates before and after nuisance regression

Nalci, A.; Luo, W.; Liu, T. T.

10.1101/603183 — neuroscience — Posted on 2019-04-09

2226 Quantification and selection of ictogenic zones in epilepsy surgery

Laiou, P.; Avramidis, E.; Lopes, M. A.; Abela, E.; Mueller, M.; Akman, O. E.; Richardson, M. P.; Rummel, C.; Schindler, K.; Goodfellow, M.

10.1101/602490 — neuroscience — Posted on 2019-04-09

2227 A global perspective on microbial diversity in the terrestrial deep subsurface

Soares, A.; Edwards, A.; An, D.; Bagnoud, A.; Bomberg, M.; Budwill, K.; Caffrey, S.; Fields, M.; Toner, B.; Gralnick, J.; Kadnikov, V.; Momper, L.; Osburn, M.; Mu, A.; Moreau, J.; Moser, D.; Purkamo, L.; Rassner, S.; Sheik, C.; Voordouw, G.; Wouters, K.; Sherwood Lollar, B.; Mitchell, A.

10.1101/602672 — microbiology — Posted on 2019-04-09

2228 Targeted gene sequencing in 6994 individuals with neurodevelopmental disorder with epilepsy

Heyne, H. O.; Artomov, M.; Battke, F.; Bianchini, C.; Smith, D.; Liebmann, N.; Tadigotla, V.; Stanley, C.; Lal, D.; Rehm, H.; Lerche, H.; Daly, M.; Helbig, I.; Biskup, S.; Weber, Y.; Lemke, J.

10.1101/602524 — genetics — Posted on 2019-04-09

2229 Nanotopography reveals metabolites that maintain the immunosuppressive phenotype of mesenchymal stem cells

Ross, E.; Turner, L.-A.; Saeed, A.; Burgess, K.; Blackburn, G.; Reynolds, P.; Wells, J.; Mountford, J.; Gadegaard, N.; Salmeron-Sanchez, M.; Oreffo, R.; Dalby, M.

10.1101/603332 — bioengineering — Posted on 2019-04-09

2230 High Throughput PET/CT Imaging Using a Multiple Mouse Imaging System

Greenwood, H. E.; Nyitrai, Z.; Mocsai, G.; Hobor, S.; Witney, T.

10.1101/602391 — bioengineering — Posted on 2019-04-09

2231 Intrinsic sensory disinhibition contributes to intrusive re-experiencing in combat veterans

Clancy, K. J.; Albizu, A.; Schmidt, N. B.; Li, W.

10.1101/602714 — neuroscience — Posted on 2019-04-09

2232 Intraperitoneal treatment with antimicrobial peptide rescues mice from a pulmonary Francisella infection

van Hoek, M.; Kaushal, A.; Bishop, B. M.; Barksdale, S.

10.1101/603233 — microbiology — Posted on 2019-04-09

2233 Composition of the holdfast polysaccharide from Caulobacter crescentus

Hershey, D. M.; Porfirio, S.; Heiss, C.; Jaehrig, B.; Azadi, P.; Fiebig, A.; Crosson, S.

10.1101/602995 — microbiology — Posted on 2019-04-09

2234 Proteome analysis of xylose metabolism in Rhodotorula toruloides during lipidproduction

Tiukova, I.; Brandenburg, J.; Blomqvist, J.; Sampels, S.; Mikkelsen, N.; Skaugen, M.; Arntzen, M. O.; Nielsen, J.; Sandgren, M.; Kerkhoven, E. J.

10.1101/601930 — microbiology — Posted on 2019-04-09

2235 Evolution of Auxin Response Factors in plants characterized by phylogenomic synteny network analyses

Gao, B.; Wang, L.; Oliver, M.; Chen, M.; Zhang, J.

10.1101/603175 — genomics — Posted on 2019-04-09

2236 Within-family studies for Mendelian randomization: avoiding dynastic, assortative mating, and population stratification biases

Brumpton, B.; Sanderson, E.; Hartwig, F. P.; Harrison, S.; Vie, G. A.; Cho, Y.; Howe, L.; Hughes, A.; Boomsma, D.; Havdahl, A.; Hopper, J.; Neale, M.; Nivard, M.; Pedersen, N.; Reynolds, C.; Tucker-Drob, E. M.; Grotzinger, A.; Howe, L.; Morris, T.; Li, S.; The Mendelian randomization within-family consorti, ; Chen, W.-M.; Bjorngaard, J. H.; Hveem, K.; Willer, C.; Evans, D.; Kaprio, J.; Davey Smith, G.; Asvold, B.; Hemani, G.; Davies, N. M.

10.1101/602516 — genetics — Posted on 2019-04-09

2237 High-throughput, image-based flow cytometry and clustering method for phenotyping heterogeneous cell populations

Peuss, R.; Box, A. C.; Accorsi, A.; Wood, C.; Sanchez Alvarado, A.; Rohner, N.

10.1101/603035 — zoology — Posted on 2019-04-09

2238 Evolved resistance to GAPDH inhibition results in loss of the Warburg Effect but retains a different state of glycolysis

Liberti, M. V.; Allen, A. E.; Ramesh, V.; Dai, Z.; Singleton, K. R.; Guo, Z.; Liu, J. O.; Wood, K. C.; Locasale, J. W.

10.1101/602557 — systems biology — Posted on 2019-04-09

2239 Systematically understanding the key roles of microglia in AD development

Ji, Z.; Liu, C.; Zhao, W.; Soto, C.; Zhou, X.

10.1101/601054 — systems biology — Posted on 2019-04-09

2240 WRKY1 mediates transcriptional crosstalk between light and nitrogen signaling pathways in Arabidopsis thaliana

Marshall-Colon, A.; Heerah, S.; Katari, M.; Coruzzi, G.

10.1101/603142 — plant biology — Posted on 2019-04-09

2241 Increased Nitrogen Fixation and Remobilization May Contribute to Higher Seed Protein Content Without a Yield Penalty in a Soybean Introgression Line

Locke, A. M.; Ramirez, M. E.

10.1101/602748 — plant biology — Posted on 2019-04-09

2242 Disruption of large-scale electrophysiological networks in stroke patients with visuospatial neglect

Ros, T.; Michela, A.; Meyer, A.; Bellman, A.; Vuadens, P.; Zermatten, V.; Saj, A.; Vuilleumier, P.

10.1101/602318 — neuroscience — Posted on 2019-04-09

2243 Potential of on-scalp MEG: Robust detection of human visual gamma-band responses

Iivanainen, J.; Zetter, R.; Parkkonen, L.

10.1101/602342 — neuroscience — Posted on 2019-04-09

2244 Prior physical synchrony enhances rapport and inter-brain synchronization during subsequent educational communication

Nozawa, T.; Sakaki, K.; Ikeda, S.; Jeong, H.; Yamazaki, S.; Kawata, K. H. d. S.; Kawata, N. Y. d. S.; Sasaki, Y.; Kulason, K.; Hirano, K.; Miyake, Y.; Kawashima, R.

10.1101/601385 — neuroscience — Posted on 2019-04-09

2245 Mapping numerical perception and operations in relation to functional and anatomical landmarks of human parietal cortex

Castaldi, E.; Vignaud, A.; Eger, E.

10.1101/602599 — neuroscience — Posted on 2019-04-09

2246 Development of specific molecular markers to distinguish and quantify broomrape species in a soil sample from infected field

Aly, R.; Bari, V. K.; Londner, A.; Marina, K.; Nassar, J. A.; Taha-Salaime, L. T.; Eizenberg, H.; Lati, R.

10.1101/602284 — molecular biology — Posted on 2019-04-09

2247 Zinc Solubilizing Plant Growth Promoting Microbes Produce Zinc Nanoparticles

Sultana, U.; Desai, S.; Reddy, G.; TNKVV, P.

10.1101/602219 — microbiology — Posted on 2019-04-09

2248 Comparative genomic analysis reveals a monophyletic cold adapted Arthrobacter cluster from polar and alpine regions

Shen, L.; Liu, Y.; Xu, B.; Wang, N.; Anslan, S.; Ren, P.; Liu, F.; Zhou, Y.; Liu, Q.

10.1101/603225 — microbiology — Posted on 2019-04-09

2249 Transcriptional response of Streptomyces coelicolor to rapid chromosome relaxation or long-term supercoiling imbalance

Szafran, M. J.; Gongerowska, M.; Małecki, T.; Elliot, M.; Jakimowicz, D.

10.1101/602359 — microbiology — Posted on 2019-04-09

2250 Not just one p: Multivariate GWAS of psychiatric disorders and their cardinal symptoms reveal two dimensions of cross-cutting genetic liabilities

Mallard, T. T.; Karlsson Linner, R.; Okbay, A.; Grotzinger, A. D.; de Vlaming, R.; Meddens, S. F. W.; Tucker-Drob, E. M.; Kendler, K.; Keller, M. C.; Koellinger, P. D.; Harden, K. P.

10.1101/603134 — genetics — Posted on 2019-04-09

2251 Integrative taxonomy confirms the species status of the Himalayan langurs, Semnopithecus schistaceus Hodgson 1840

Arekar, K.; S, S.; Karanth, P.

10.1101/602243 — evolutionary biology — Posted on 2019-04-09

2252 Assessment and representation of variability in ecological niche model predictions

Cobos, M. E.; Osorio-Olvera, L.; Peterson, A. T.

10.1101/603100 — bioinformatics — Posted on 2019-04-09

2253 MuGVRE. A virtual research environment for 3D/4D genomics

Codo, L.; Bayarri, G.; Alvarex-Cid-Fuentes, J.; Conejero, J.; Hospital, A.; Royo, R.; Repchevsky, D.; Pasi, M.; Meletiou, A.; McDowall, M. D.; Reham, F.; Alcantara, J. A.; Jimenez-Garcia, B.; Walther, J.; Illa, R.; Serra, F.; Goodstadt, M.; Castillo, D.; Sati, S.; Buitrago, D.; Brun-Heath, I.; Fernandez-Recio, J.; Cavalli, G.; Marti-Renom, M. A.; Yates, A.; Laughton, C. A.; Badia, R. M.; Orozco, M.; Gelpi, J. L.

10.1101/602474 — bioinformatics — Posted on 2019-04-09

2254 Temporal processing of facial expressions of mental states

Schmidtmann, G.; Jordan, M.; Loong, J. T.; Logan, A. J.; Carbon, C.-C.; Gold, I.

10.1101/602375 — animal behavior and cognition — Posted on 2019-04-09

2255 Modeling place cells and grid cells in multi-compartment environments: hippocampal-entorhinal loop as a multisensory integration circuit

Li, T.; Arleo, A.; Sheynikhovich, D.

10.1101/602235 — animal behavior and cognition — Posted on 2019-04-09

2256 Molecular Identification and Characterization of Two Rubber Dandelion Amalgaviruses

Debat, H. J.; Luo, Z.; Iaffaldano, B. J.; Zhuang, X.; Cornish, K.

10.1101/229443 — microbiology — Posted on 2019-04-09

2257 EpiGraph: an open-source platform to quantify epithelial organization

Vicente-Munuera, P.; Gomez-Galvez, P. J.; Tetley, R. J.; Forja, C.; Tagua, A.; Letran, M.; Tozluoglu, M.; Mao, Y.; Escudero, L. M.

10.1101/217521 — developmental biology — Posted on 2019-04-09

2258 Empirical evidence reveals the phase diagram of patch patterns in Mediterranean drylands

Meloni, F.; Nakamura, G. M.; Granzotti, C. R. F.; Martinez, A. S.

10.1101/171835 — ecology — Posted on 2019-04-09

2259 A randomized, double blind study of computerized cognitive training in combination with transcranial direct current stimulation (tDCS) in stroke patients - utility of fMRI as marker for training outcome

Kolskaar, K. K.; Richard, G.; Alnaes, D.; Dorum, E. S.; Sanders, A.-M.; Ulrichsen, K. M.; Monereo Sanchez, J.; Ihle-Hansen, H.; Nordvik, J. E.; Westlye, L. T.

10.1101/603985 — neuroscience — Posted on 2019-04-09

2260 Pigeon foot feathering reveals conserved limb identity networks

Boer, E. F.; Van Hollebeke, H. F.; Park, S.; Infante, C. R.; Menke, D. B.; Shapiro, M. D.

10.1101/602987 — developmental biology — Posted on 2019-04-09

2261 Pairing interactions between nucleobases and ligands in aptamer:ligand complexes of riboswitches: Crystal structure analysis, classification, optimal structures and accurate interaction energies

Prabhakar, P. S.; Sharma, P.; Mitra, A.

10.1101/603159 — biophysics — Posted on 2019-04-09

2262 Widespread FUS mislocalization is a molecular hallmark of ALS

Tyzack, G. E.; Luisier, R.; Taha, D. M.; Neeves, J.; Modic, M.; Mitchell, J. S.; Meyer, I.; Greensmith, L.; Newcombe, J.; Ule, J.; Luscombe, N. M.; Patani, R.

10.1101/491787 — neuroscience — Posted on 2019-04-09

2263 Mayaro virus replication restriction and induction of muscular inflammation in mice are dependent on age and type-I interferon response

Figueiredo, C. M.; Neris, R. L. S.; Gavino-Leopoldino, D.; Almeida, J. S.; Dos-Santos, J. S.; Figueiredo, C. P.; Bellio, M.; Bozza, M. T.; Assuncao-Miranda, I.

10.1101/602920 — microbiology — Posted on 2019-04-09

2264 Dorsoventral dissociation of Hox gene expression underpins the diversification of molluscs

Huan, P.; Wang, Q.; Tan, S.; Liu, B.

10.1101/603092 — developmental biology — Posted on 2019-04-09

2265 Ancestral role of Fat-like cadherins in planar cell polarity

Brooun, M.; Klimovich, A.; Bashkurov, M.; Pearson, B. J.; Steele, R. E.; McNeill, H.

10.1101/602029 — developmental biology — Posted on 2019-04-09

2266 West Nile Virus Subverts T Cell Stimulatory Capacity of Human Dendritic Cells

Zimmerman, M. G.; Bowen, J. R.; McDonald, C. E.; Pulendran, B.; Suthar, M. S.

10.1101/602839 — microbiology — Posted on 2019-04-09

2267 RhoG and Cdc42 can contribute to Rac-dependent lamellipodia formation through WAVE Regulatory Complex-binding

Schaks, M.; Doering, H.; Kage, F.; Steffen, A.; Kluenemann, T.; Blankenfeldt, W.; Stradal, T.; Rottner, K.

10.1101/603340 — cell biology — Posted on 2019-04-09

2268 Hematological and Neurological Expressed 1 (HN1): a predictive and pharmacodynamic biomarker of metformin response in endometrial cancers.

Bateman, N. W.; Teng, P.-n.; Hope, E.; Hood, B.; Oliver, J.; Ao, W.; Zhou, M.; Wang, G.; Tommarello, D.; Wilson, K.; Conrads, K. A.; Hamilton, C. A.; Darcy, K.; Casablanca, Y.; Maxwell, G. L.; Bae-Jump, V.; Conrads, T. P.

10.1101/602870 — cancer biology — Posted on 2019-04-09

2269 Automated design of highly diverse riboswitches

Wu, M. J.; Andreasson, J. O.; Kladwang, W.; Greenleaf, W. J.; Das, R.

10.1101/603001 — biophysics — Posted on 2019-04-09

2270 Differential nanoscale organisation of LFA-1 modulates T cell migration

Shannon, M.; Pineau, J.; Griffie, J.; Aaron, J.; Peel, T.; Williamson, D.; Zamoyska, R.; Cope, A.; Cornish, G.; Owen, D.

10.1101/602326 — immunology — Posted on 2019-04-09

2271 Role of host genetic diversity for susceptibility-to-infection in the evolution of virulence of a plant virus

Gonzalez, R.; Butkovic;, A.; Elena, S. F.

10.1101/602201 — evolutionary biology — Posted on 2019-04-09

2272 N-Glycome regulation limits the transdifferentiation of endothelial cells into hematopoietic stem cells

Kasper, D.; Wu, Y.; Mandl, H. K.; Salina, K.; Ghersi, J.; Hintzen, J.; Armerp, W.; He, Z.; Heindel, D. W.; Park, E. J.; Sessa, W.; Mahal, L.; Hirschi, K.; Nicoli, S.

10.1101/602912 — developmental biology — Posted on 2019-04-09

2273 Cell adhesion molecule interaction with Piezo1 channels is a mechanism for sub cellular regulation of mechanical sensitivity

Chuntharpursat-Bon, E.; Povstyan, O. V.; Ludlow, M. J.; Gaunt, H. J.; Baxter, P. D.; Beech, D. J.

10.1101/602532 — cell biology — Posted on 2019-04-09

2274 Coupled MCMC in BEAST 2

Mueller, N. F.; Bouckaert, R.

10.1101/603514 — evolutionary biology — Posted on 2019-04-09

2275 Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity

Heden, T. D.; Johnson, J. M.; Ferrara, P. J.; Eshima, H.; Verkerke, A. R.; Wentzler, E. J.; Siripoksup, P.; Narowski, T. M.; Coleman, C. B.; Lin, C.-T.; Ryan, T. E.; Reidy, P. T.; de Castro Bras, L. E.; Karner, C. M.; Burant, C. F.; Maschek, J. A.; Cox, J. E.; Mashek, D. G.; Kardon, G.; Boudina, S.; Zeczycki, T. N.; Rutter, J.; Shaikh, S. R.; Vance, J. E.; Drummond, M. J.; Neufer, P. D.; Funai, K.

10.1101/599985 — physiology — Posted on 2019-04-09

2276 Impaired speed encoding is associated with reduced grid cell periodicity in a mouse model of tauopathy

Ridler, T.; Witton, J.; Phillips, K. G.; Randall, A. D.; Brown, J. T.

10.1101/595652 — neuroscience — Posted on 2019-04-09

2277 Active head motion reduction in Magnetic Resonance Imaging using tactile feedback

Krause, F.; Benjamins, C.; Eck, J.; Luehrs, M.; van Hoof, R.; Goebel, R.

10.1101/595777 — neuroscience — Posted on 2019-04-09

2278 Integrative functional genomics decodes herpes simplex virus 1

Whisnant, A. W.; Juerges, C. S.; Hennig, T.; Wyler, E.; Prusty, B.; Rutkowski, A. J.; L'Hernault, A.; Goebel, M.; Doering, K.; Menegatti, J.; Antrobus, R.; Matheson, N. J.; Kuenzig, F. W.; Mastrobuoni, G.; Bielow, C.; Kempa, S.; Chunguang, L.; Dandekar, T.; Zimmer, R.; Landthaler, M.; Graesser, F.; Lehner, P. J.; Friedel, C. C.; Erhard, F.; Doelken, L.

10.1101/603654 — microbiology — Posted on 2019-04-09

2279 The Prevotella copri complex comprises four distinct clades that are underrepresented in Westernised populations

Tett, A.; Huang, K. D.; Asnicar, F.; Fehlner-Peach, H.; Pasolli, E.; Karcher, N.; Armanini, F.; Manghi, P.; Bonham, K.; Zolfo, M.; De Filippis, F.; Magnabosco, C.; Bonneau, R.; Lusingu, J.; Amuasi, J.; Reinhard, K.; Rattei, T.; Boulund, F.; Engstrand, L.; Zink, A.; Collado, M. C.; Littman, D. R.; Eibach, D.; Ercolini, D.; Rota-Stabelli, O.; Huttenhower, C.; Maixner, F.; Segata, N.

10.1101/600593 — microbiology — Posted on 2019-04-09

2280 Gene modules associated with human diseases revealed by network analysis

Ma, S.; Gong, J.; Zuo, W.; Geng, H.; Zhang, Y.; Wang, M.; Han, E.; Peng, J.; Wang, Y.; Wang, Y.; Chen, Y.

10.1101/598151 — systems biology — Posted on 2019-04-09

2281 Modulating dream experience: Noninvasive brrain stimulation over the sensorimotor cortex reduces dream movement

Noreika, V.; Windt, J. M.; Kern, M.; Valli, K.; Salonen, T.; Parkkola, R.; Revonsuo, A.; Karim, A. A.; Ball, T.; Lenggenhager, B.

10.1101/600288 — neuroscience — Posted on 2019-04-09

2282 Correlation Of Microglial Activation With White Matter Changes In Dementia With Lewy Bodies

Nicastro, N.; Mak, E.; Williams, G. B.; Surendranathan, A.; Bevan-Jones, W. R.; Passamonti, L.; Vazquez-Rodriguez, P.; Su, L.; Arnold, R.; Aigbirhio, F. I.; Rowe, J. B.; O'Brien, J. T.

10.1101/599241 — neuroscience — Posted on 2019-04-09

2283 Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli

Jindal, S.; Yang, L.; Day, P.; Kell, D.

10.1101/603688 — microbiology — Posted on 2019-04-09

2284 Immunomodulatory effects of extract of Ganoderma lucidum basidiocarps cultivated on alternative substrate

Bozic Nedeljkovic, B.; Cilerdzic, J.; Zmijanjac, D.; Markovic, M.; Vasilijic, S.; Stajic, M.; Vucevic, D.

10.1101/603498 — immunology — Posted on 2019-04-09

2285 Subcellular compartments interplay for carbon and nitrogen allocation in Chromera velia and Vitrella brassicaformis

Fussy, Z.; Faitova, T.; Obornik, M.

10.1101/603555 — genomics — Posted on 2019-04-09

2286 Genomic Selection in Rubber Tree Breeding: A Comparison of Models and Methods for dealing with G x E

Souza, L. M. d.; Francisco, F. R.; Goncalves, P. d. S.; Scaloppi-Junior, E. J.; Le Guen, V.; Fritsche-Neto, R.; Souza, A. P. d.

10.1101/603662 — genetics — Posted on 2019-04-09

2287 DNA Methylation Associated with Postpartum Depressive Symptoms Overlaps Findings from a Genome-wide Association Meta-Analysis of Depression

Lapato, D. M.; Roberson-Nay, R.; Kirkpatrick, R. M.; Webb, B. T.; York, T. P.; Kinser, P.

10.1101/600742 — genetics — Posted on 2019-04-09

2288 Risk of recurrent pregnancy loss in the Ukrainian population using a combined effect of genetic variants

Loizidou, E. M.; Kucherenko, A.; Tatarskyy, P.; Chernushyn, S.; Livshyts, G. B.; Gulkovskyi, R.; Vorobiova, I. I.; Antipkin, Y.; Gorodna, O. V.; Kaakinen, M. A.; Prokopenko, I.; Livshits, L.

10.1101/603431 — genetics — Posted on 2019-04-09

2289 A novel tool for monitoring endogenous human MYC transcription and translation by EGFP tag insertion at the 3’ end using CRISPR-Cas9 genome editing

Cumbal, N.; Cole, M. D.

10.1101/603746 — cancer biology — Posted on 2019-04-09

2290 OscoNet: Inferring oscillatory gene networks

Boukouvalas, A.; Cutillo, L.; Marinopoulou, E.; Papalopulu, N.; Rattray, M.

10.1101/600049 — bioinformatics — Posted on 2019-04-09

2291 Using balances to engineer features for the classification of health biomarkers: a new approach to balance selection

Quinn, T.; Erb, I.

10.1101/600122 — bioinformatics — Posted on 2019-04-09

2292 Engineering a seven enzyme biotransformation using mathematical modelling and characterized enzyme parts

Finnigan, W.; Cutlan, R.; Snajdrova, R.; Adams, J. P.; Littlechild, J. A.; Harmer, N.

10.1101/603795 — biochemistry — Posted on 2019-04-09

2293 The receptor-like kinases BAM1 and BAM2 promote the cell-to-cell movement of miRNA in the root stele to regulate xylem patterning

Fan, P.; Wang, H.; Xue, H.; Rosas-Diaz, T.; Tang, W.; Zhang, H.; Xu, L.; Lozano-Duran, R.

10.1101/603415 — plant biology — Posted on 2019-04-09

2294 Nanopore sequencing and comparative genome analysis confirm lager-brewing yeasts originated from a single hybridization

Salazar, A. N.; Gorter de Vries, A.; van den Broek, M.; Brouwers, N.; de la Torre Cortes, P.; Kuijpers, N.; Daran, J.-M. G.; Abeel, T.

10.1101/603480 — bioinformatics — Posted on 2019-04-09

2295 Exploring the link between adenine DNA methylation and 3D genome organization in the parasite Trichomonas vaginalis

Lizarraga, A.; Klapholz OBrown, Z.; Roach, L.; Lieberman Greer, E.; Strobl-Mazzulla, P. H.; de Miguel, N.

10.1101/603894 — microbiology — Posted on 2019-04-09

2296 MEDICAL XENOPHOBIA: THE VOICES OF WOMEN REFUGEES IN DURBAN, KWAZULU-NATAL, SOUTH AFRICA

Munyaneza, Y.; Mhlongo, E. M.

10.1101/603753 — epidemiology — Posted on 2019-04-09

2297 Modulated Zika virus NS1 conjugate offers advantages for accurate detection of Zika virus specific antibody in double antigen binding and Ig capture enzyme immunoassays

Tedder, R. S.; Dicks, S.; Ijaz, S.; Santiago de Souza, N. C.; Vincente de Paula, A.; Levy, F.; Medialdea-Carrera, R.; Levi, J. E.; Pannuti, C. S.; Carvalho de Sequeira, P.; Brown, D. W.; Ushiro Lumb, I.

10.1101/603811 — microbiology — Posted on 2019-04-09

2298 Paired design of ATP bioluminescence method and colony counting method: whether it is suitable for evaluating the disinfection effect of environmental surface?

Xu, H.; Liang, J.; WANG, Y.; WANG, B.; ZHANG, T.; LIU, X.; GONG, L.

10.1101/603860 — microbiology — Posted on 2019-04-09

2299 Deciphering the mechanoresponsive role of β-catenin in Keratoconus epithelium

Janakiraman, N.; Chatterjee, A.; Padmanabhan, P.

10.1101/603738 — cell biology — Posted on 2019-04-09

2300 The physiological response in the mammary gland to Escherichia coli infection reflects a conflict between glucose need for milk production and immune response

Leitner, G.; Blum, S. E.; Heller, D. E.; Jacoby, S.; Krifucks, O.; Merin, U.; Silanikove, N.

10.1101/603845 — physiology — Posted on 2019-04-09

2301 Mode of action of the antimicrobial peptide Mel4 is independent of Staphylococcus aureus cell membrane permeability

Yasir, M.; Dutta, D.; Willcox, M. D. P.

10.1101/603712 — microbiology — Posted on 2019-04-09

2302 Preparation and characterization of phospholipid stabilized nanoemulsions in small-scale

Gurung, S.; Holzer, M.; Barnert, S.; Schubert, R.

10.1101/603803 — biophysics — Posted on 2019-04-09

2303 Luteal progesterone level correlated with immunotherapy success of patients with repeated implantation failures

Sefrioui, O.; Madkour, A.; Bouamoud, N.; Kaarouch, I.; Saadani, B.; Amzazi, S.; Copin, H.; Benkhalifa, M.; Louanjli, N.

10.1101/603720 — immunology — Posted on 2019-04-09

2304 Composition and structure of synaptic ectosomes exporting antigen receptor linked to functional CD40 ligand from helper T-cells

Saliba, D. G.; Cespedes-Donoso, P. F.; Balint, S.; Compeer, E. B.; Valvo, S.; Korobchevskaya, K.; Mayya, V.; Peng, Y.; Dong, T.; Tognoli, M.-L.; O Neill, E.; Bonham, S.; Fischer, R.; Kessler, B. M.; Dustin, M. L.

10.1101/600551 — immunology — Posted on 2019-04-09

2305 The full-length transcriptome of C. elegans using direct RNA sequencing

Roach, N. P.; Sadowski, N.; Alessi, A. F.; Timp, W.; Taylor, J.; Kim, J. K.

10.1101/598763 — genomics — Posted on 2019-04-09

2306 Growth-coupled overproduction is theoretically possiblefor most metabolites in Saccharomyces cerevisiae under anaerobic condition

Tamura, T.

10.1101/563437 — bioinformatics — Posted on 2019-04-09

2307 Ancient tropical extinctions contributed to the latitudinal diversity gradient

Meseguer, A. S.; Condamine, F. L.

10.1101/236646 — evolutionary biology — Posted on 2019-04-09

2308 Ultra-local adaptation due to genetic accommodation

Sun, S.-J.; Catherall, A.; Pascoal, S.; Jarrett, B.; Miller, S.; Sheehan, M.; Kilner, R.

10.1101/598292 — evolutionary biology — Posted on 2019-04-09

2309 Knowledge, attitude and practices on dengue fever among paediatric and adult in-patients in Metro Manila, Philippines

Herbuela, V. R. D. M.; de Guzman, F. S.; Sobrepena, G. D.; Claudio, A. B. F.; Tomas, A. C. V.; Arriola-delos Reyes, C. M.; Regalado, R. A.; Teodoro, M. M.; Watanabe, K.

10.1101/520981 — epidemiology — Posted on 2019-04-09

2310 Basal Contamination of Bulk Sequencing: Lessons from the GTEx dataset

Nieuwenhuis, T. O.; Yang, S.; Pillalamarri, V.; Arking, D.; Rosenberg, A. Z.; McCall, M. N.; Halushka, M. K.

10.1101/602367 — genomics — Posted on 2019-04-08

2311 ecTMB: a robust method to estimate and classify tumor mutational burden

Yao, L.; Fu, Y.; Mohiyuddin, M.; Lam, H.

10.1101/602060 — bioinformatics — Posted on 2019-04-08

2312 Ribo-seQC: comprehensive analysis of cytoplasmic and organellar ribosome profiling data

Calviello, L.; Sydow, D.; Harnett, D.; Ohler, U.

10.1101/601468 — bioinformatics — Posted on 2019-04-08

2313 In Search of Consciousness: Examining the Temporal Dynamics of Conscious Visual Perception using MEG time-series data

Mai, A.-T.; Grootswagers, T.; Carlson, T. A.

10.1101/603043 — neuroscience — Posted on 2019-04-08

2314 Neuronal differentiation through GPI-anchor cleavage by GDE2: regulation via sequence-dependent trafficking

Salgado-Polo, F.; van Veen, M.; van den Broek, B.; Leyton Puig, D.; Perrakis, A.; Moolenaar, W. H.; Matas-Rico, E.

10.1101/532499 — neuroscience — Posted on 2019-04-08

2315 Rift Valley fever virus minigenome system for investigating the role of L protein residues in viral transcription and replication

Jerome, H.; Rudolf, M.; Lelke, M.; Pahlmann, M.; Busch, C.; Bockholt, S.; Wurr, S.; Gunther, S.; Rosenthal, M.; Kerber, R.

10.1101/556738 — molecular biology — Posted on 2019-04-08

2316 Untangling the dynamics of persistence and colonization in microbial communities

Ranjeva, S. L.; Mihaljevic, J. R.; Joseph, M. B.; Giuliano, A. R.; Dwyer, G.

10.1101/427542 — ecology — Posted on 2019-04-08

2317 Modeling enamel matrix secretion in mammalian teeth

Hakkinen, T. J.; Sova, S. S.; Corfe, I. J.; Tjaderhane, L.; Hannukainen, A.; Jernvall, J.

10.1101/525162 — biophysics — Posted on 2019-04-08

2318 High-Speed Automatic Characterization of Rare Events in Flow Cytometric Data

Qi, Y.; Fang, Y.; Sinclair, D. R.; Guo, S.; Alberich-Jorda, M.; Lu, J.; Tenen, D. G.; Kharas, M. G.; Pyne, S.

10.1101/591644 — bioinformatics — Posted on 2019-04-08

2319 Statistically consistent divide-and-conquer pipelines for phylogeny estimation using NJMerge

Molloy, E. K.; Warnow, T.

10.1101/469130 — evolutionary biology — Posted on 2019-04-08

2320 Functional genomics of a symbiotic community: shared traits in the olive fruit fly gut microbiota

Blow, F.; Gioti, A.; Goodhead, I. B.; Kalyva, M.; Kampouraki, A.; Vontas, J.; Darby, A. C.

10.1101/590489 — evolutionary biology — Posted on 2019-04-08

2321 Random forest-based modelling to detect biomarkers for prostate cancer progression

Toth, R.; Schiffmann, H.; Hube-Magg, C.; Büscheck, F.; Höflmayer, D.; Weidemann, S.; Lebok, P.; Fraune, C.; Minner, S.; Schlomm, T.; Sauter, G.; Plass, C.; Assenov, Y.; Simon, R.; Meiners, J.; Gerhauser, C.

10.1101/602334 — cancer biology — Posted on 2019-04-08

2322 Myelin Basic Protein dynamics from out-of-equilibrium functional state to degraded state in myelin

Di Gioacchino, M.; Bianconi, A.; Burghammer, M.; Ciasca, G.; Bruni, F.; Campi, G.

10.1101/602441 — biophysics — Posted on 2019-04-08

2323 ViraMiner: deep learning on raw DNA sequences for identifying viral genomes in human samples

Tampuu, A.; Bzhalava, Z.; Dillner, J.; Vicente, R.

10.1101/602656 — bioinformatics — Posted on 2019-04-08

2324 Intestinal peroxisomal fatty acid β-oxidation regulates neural serotonin signaling through a feedback mechanism

Bouagnon, A. D.; Srivastava, S.; Panda, O.; Schroeder, F.; Srinivasan, S.; Ashrafi, K.

10.1101/602649 — physiology — Posted on 2019-04-08

2325 RNA polymerase II plays an active role in the formation of gene loops through the Rpb4 subunit

Allepuz-Fuster, P.; O'Brien, M. J.; Gonzalez-Polo, N.; Pereira, B.; Dhoondia, Z.; Ansari, A.; Calvo, O.

10.1101/602227 — molecular biology — Posted on 2019-04-08

2326 Meiotic cellular rejuvenation is coupled to nuclear remodeling in budding yeast

Ünal, E.; King, G. A.; Goodman, J. S.; Chetlapalli, K.; Schick, J. G.; Jorgens, D. M.; McDonald, K. L.

10.1101/602433 — cell biology — Posted on 2019-04-08

2327 Citizen scientists highlight conservation value of a small subtropical reef, Flinders Reef, southeast Queensland, Australia.

Grol, M. G.; Vercelloni, J.; Kenyon, T. M.; Bayraktarov, E.; van den Berg, C. P.; Harris, D.; Loder, J. A.; Mihaljevic, M.; Rowland, P. I.; Roelfsema, C. M.

10.1101/602631 — ecology — Posted on 2019-04-08

2328 In-Silico Analysis of nsSNPs Associated with CYP11B2 Gene

Tariq, M.; Arooj, A.; Gillani, Z.; Tufail, A.; Chaudhry, M. T.; Babar, M. E.; Chohan, T. A.

10.1101/602615 — bioinformatics — Posted on 2019-04-08

2329 Neural Correlates of Causal Confounding

Liljeholm, M.

10.1101/395707 — neuroscience — Posted on 2019-04-08

2330 Consequences of PCA graphs, SNP codings, and PCA variants for elucidating population structure

Gauch, H. G.; Qian, S.; Piepho, H.-P.; Zhou, L.; Chen, R.

10.1101/393611 — genomics — Posted on 2019-04-08

2331 MYO19 interacts weakly with Miro2 GTPases on the mitochondrial outer membrane

Bocanegra, J. L.; Fujita, B. M.; Melton, N. R.; Cowan, J. M.; Schinski, E. L.; Tamir, T. Y.; Major, M. B.; Quintero, O. A.

10.1101/602938 — cell biology — Posted on 2019-04-08

2332 Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1

Ehlen, A.; Martin, C.; Miron, S.; Julien, M.; Theillet, F. X.; Boucherit, V.; Ropars, V.; Duchambon, P.; El Marjou, A.; Zinn Justin, S.; Carreira, A.

10.1101/265934 — cell biology — Posted on 2019-04-08

2333 Sibe: a computation tool to apply protein sequence statistics to folding and design

Cheung, N. J.; Yu, W.

10.1101/380576 — bioinformatics — Posted on 2019-04-08

2334 FIN-Seq: Transcriptional profiling of specific cell types in frozen archived tissue from the human central nervous system

Amamoto, R.; Zuccaro, E.; Curry, N. C.; Khurana, S.; Chen, H.-H.; Cepko, C. L.; Arlotta, P.

10.1101/602847 — neuroscience — Posted on 2019-04-08

2335 Evolution of neocortical folding: A phylogenetic comparative analysis of MRI from 34 primate species

Heuer, K.; Gulban, O. F.; Bazin, P.-L.; Osoianu, A.; Valabregue, R.; Santin, M.; Herbin, M.; Toro, R.

10.1101/379750 — neuroscience — Posted on 2019-04-08

2336 Cas12a trans-cleavage can be modulated in vitro and is active on ssDNA, dsDNA, and RNA

Fuchs, R. T.; Curcuru, J. L.; Mabuchi, M.; Yourik, P.; Robb, G. B.

10.1101/600890 — molecular biology — Posted on 2019-04-08

2337 Divergent neural pathways emanating from the lateral parabrachial nucleus mediate distinct components of the pain response

Chiang, M. C.; Nguyen, E. K.; Papale, A. E.; Ross, S. E.

10.1101/602466 — neuroscience — Posted on 2019-04-08

2338 Evaluation of nutrient stoichiometric relationships amongst ecosystem compartments of a subtropical treatment wetland. Do we have \"Redfield Wetlands\"?

Julian, P.; Gerber, S.; Bhomia, R.; King, J.; Osborne, T. Z.; Wright, A. L.; Power, M.; Dombrowski, J.

10.1101/220186 — ecology — Posted on 2019-04-08

2339 Prospects for transcranial temporal interference stimulation in humans: a computational study

Rampersad, S.; Roig-Solvas, B.; Yarossi, M.; Kulkarni, P. P.; Santarnecchi, E.; Dorval, A. D.; Brooks, D. H.

10.1101/602102 — biophysics — Posted on 2019-04-08

2340 Evolution-guided engineering of small-molecule biosensors

Snoek, T.; Chaberski, E. K.; Ambri, F.; Kol, S.; Bjoern, S. P.; Pang, B.; Barajas, J. F.; Welner, D. H.; Jensen, M. K.; Keasling, J. D.

10.1101/601823 — synthetic biology — Posted on 2019-04-08

2341 Discovery Of UFO Proteins: Human-Virus Chimeric Proteins Generated During Influenza Virus Infection

Ma, Y.; Angel, M.; Wang, G.; Ho, J. S. Y.; Zhao, N.; Noel, J.; Moshkina, N.; Gibbs, J.; Wei, J.; Rosenberg, B.; Johnson, J.; Chang, M.; Peralta, Z.; Krogan, N.; Benner, C.; van Bakel, H.; Łuksza, M.; Greenbaum, B. D.; Miraldi, E. R.; Garcia-Sastre, A.; Yewdell, J. W.; Marazzi, I.

10.1101/597617 — microbiology — Posted on 2019-04-08

2342 Lethal mutagenesis of Rift Valley fever virus induced by favipiravir

Borrego, B.; de Avila, A. I.; Domingo, E.; Brun, A.

10.1101/601344 — microbiology — Posted on 2019-04-08

2343 Complement in human pre-implantation embryos: attack and defense

Parnov Reichhardt, M.; Lundin, K.; Lokki, A. I.; Recher, G.; Vuoristo, S.; Katayama, S.; Tapanainen, J.; Kere, J.; Meri, S.; Tuuri, T.

10.1101/595561 — developmental biology — Posted on 2019-04-08

2344 A Comprehensive Molecular Portrait of Human Urine-derived Renal Progenitor Cells

Rahman, M. S.; Wruck, W.; Spitzhorn, L.-S.; Bohndorf, M.; Martins, S.; Asar, F.; Ncube, A.; Erichsen, L.; Graffmann, N.; Adjaye, J.

10.1101/602417 — developmental biology — Posted on 2019-04-08

2345 Signalling involving MET and FAK supports cell division independent of the activity of the cell cycle-regulating CDK4/6 kinases

Zhang, C.; Stockwell, S. R.; Elbanna, M.; Ketteler, R.; Freeman, J.; Al-Lazikani, B.; Eccles, S.; De Haven Brandon, A.; Raynaud, F.; Hayes, A.; Clarke, P. A.; Workman, P.; Mittnacht, S.

10.1101/601799 — cancer biology — Posted on 2019-04-08

2346 Detection of glioma and prognostic subtypes by non-invasive circulating cell-free DNA methylation markers

Noushmehr, H.; Sabedot, T. S.; Malta, T. M.; Nelson, K.; Snyder, J.; Wells, M.; deCarvalho, A.; Makherjee, A.; Chitale, D.; Mosella, M.; Asmaro, K.; Robin, A. M.; Rosenblum, M. L.; Mikkelsen, T.; Rock, J.; Poisson, L. M.; Lee, I. Y.; Walbert, T.; Kalkanis, S.; Castro, A. V.

10.1101/601245 — cancer biology — Posted on 2019-04-08

2347 Function and clinical relevance of RHAMM isoforms in pancreatic tumor progression

Choi, S.; Wang, D.; Chen, X.; Tang, L. H.; Verma, A.; Chen, Z.; Kim, B. J.; Selesner, L.; Robzyk, K.; Zhang, G.; Pang, S.; Han, T.; Chan, C. S.; Fahey, T. J.; Elemento, O.; Du, Y.-C. N.

10.1101/598334 — cancer biology — Posted on 2019-04-08

2348 Oregano essential oil vapour prevents Plasmopora viticola infection in grapevine (Vitis Vinifera) by triggering autoimmune metabolic pathways

Rienth, M.; Crovadore, J.; Ghaffari, S.; Lefort, F.

10.1101/602730 — plant biology — Posted on 2019-04-08

2349 Identifying TCDD-resistance genes via murine and rat comparative genomics and transcriptomics

Prokopec, S. D.; Lu, A.; Lee, S. C.-E. S.; Yao, C. Q.; Sun, R. X.; Watson, J. D.; de Borja, R.; Wong, A.; Sam, M.; Zuzarte, P.; McPherson, J. D.; Okey, A. B.; Pohjanvirta, R.; Boutros, P. C.

10.1101/602698 — genomics — Posted on 2019-04-08

2350 Neutrophil Extracellular Traps contribute to the pathogenesis of leprosy type 2 reactions

da Silva, C. O.; Dias, A. A.; Nery, J. A.; Machado, A.; Ferreira, H.; Santos, J. P.; Nadaes, N.; Sarno, E. N.; Saraiva, E. M.; Schmitz, V.; Pessolani, M. C. V.

10.1101/602722 — immunology — Posted on 2019-04-08

2351 Large-scale Lassa fever outbreaks in Nigeria: quantifying the association between disease reproduction number and local rainfall

ZHAO, S. F.; MUSA, S. S.; Fu, H.; He, D.; Qin, J.

10.1101/602706 — epidemiology — Posted on 2019-04-08

2352 A Network Architecture for Bidirectional Neurovascular Coupling in Rat Whisker Barrel Cortex

Kumar, B. S.; Khot, A.; Chakravarthy, V. S.; Pushpavanam, S.

10.1101/602680 — neuroscience — Posted on 2019-04-08

2353 Ventriculo-arterial uncoupling is associated with VO2 dependency in cardiac surgical patients

Guinot, P.-G.; Nguyen, M.; Huette, P.; Abou-Arab, O.; Bouhemad, B.; Longrois, D.

10.1101/602607 — physiology — Posted on 2019-04-08

2354 Suppression of transcytosis regulates zebrafish blood-brain barrier development

O'Brown, N. M.; Megason, S. G.; Gu, C.

10.1101/596221 — developmental biology — Posted on 2019-04-08

2355 Odor-background segregation of unknown odorants based on stimulus onset asynchrony in honey bees

Sehdev, A.; Szyszka, P.

10.1101/602045 — neuroscience — Posted on 2019-04-08

2356 Dynamic chromosome rearrangements of the white-spotted bamboo shark shed light on cartilaginous fish diversification mechanisms

Zhang, Y.; Gao, H.; Li, H.; Guo, J.; Wang, M.; Xu, Q.; Wang, J.; Lv, M.; Guo, X.; Liu, Q.; Wei, L.; Ren, H.; Xi, Y.; Guo, Y.; Zhao, Q.; Pan, S.; Liu, C.; Sang, L.; Ding, X.; Wang, C.; Xiang, H.; Song, Y.; Liu, Y.; Liu, S.; Jiang, Y.; Shao, C.; Shi, J.; Liu, S.; Sabir, J. S. M.; Sabir, M. J.; Khan, M.; Hajrah, N. H.; Lee, S. M.-Y.; Xu, X.; Yang, H.; Wang, J.; Fan, G.; Yang, N.; Liu, X.

10.1101/602136 — genomics — Posted on 2019-04-08

2357 Metapopulation connectedness and the evolution of multiple life-history traits

Masier, S.; Bonte, D.

10.1101/476093 — ecology — Posted on 2019-04-08

2358 Disease networks and their contribution to disease understanding and drug repurposing: Evolution of the concept, techniques and data sources

Garcia del Valle, E.; Lagunes Garcia, G.; Prieto Santamaria, L.; Zanin, M.; Menasalvas Ruiz, E.; Rodriguez Gonzalez, A.

10.1101/415257 — bioinformatics — Posted on 2019-04-08

2359 DISNET: A framework for extracting phenotypic disease information from public sources

Lagunes Garcia, G.; Rodriguez Gonzalez, A.; Prieto Santamaria, L.; Garcia del Valle, E. P.; Zanin, M.; Menasalvas Ruiz, E.

10.1101/428201 — bioinformatics — Posted on 2019-04-08

2360 Fine-scale ecological and transcriptomic data reveal niche differentiation of an allopolyploid from diploid parents in Cardamine

Akiyama, R.; Sun, J.; Hatakeyama, M.; Lischer, H. E. L.; Briskine, R. V.; Hay, A.; Gan, X.; Tsiantis, M.; Kudoh, H.; Kanaoka, M. M.; Sese, J.; Shimizu, K. K.; Shimizu-Inatsugi, R.

10.1101/600783 — plant biology — Posted on 2019-04-08

2361 Precocious neuronal differentiation and disrupted oxygen responses in Kabuki syndrome

Carosso, G. A.; Boukas, L.; Augustin, J. J.; Nguyen, H. N.; Winer, B. L.; Cannon, G. H.; Robertson, J. D.; Zhang, L.; Hansen, K. D.; Goff, L. A.; Bjornsson, H. T.

10.1101/484410 — neuroscience — Posted on 2019-04-08

2362 Fundamental Law of Memory Recall

Naim, M.; Katkov, M.; Tsodyks, M.

10.1101/510750 — neuroscience — Posted on 2019-04-08

2363 Impairments in sensory-motor gating and information processing in a mouse model of Ehmt1 haploinsufficiency

Davis, B. A.; David, F.; O'Regan, C.; Adam, M.; Harwood, A.; Crunelli, V.; Isles, A.

10.1101/257626 — neuroscience — Posted on 2019-04-08

2364 Inferring infectious disease phylodynamics with notification data

Duchene, S.; Di Giallonardo, F.; Holmes, E. C.; Vaughan, T.

10.1101/596700 — evolutionary biology — Posted on 2019-04-08

2365 KofamKOALA: KEGG ortholog assignment based on profile HMM and adaptive score threshold

Aramaki, T.; Blanc-Mathieu, R.; Endo, H.; Ohkubo, K.; Kanehisa, M.; Goto, S.; Ogata, H.

10.1101/602110 — bioinformatics — Posted on 2019-04-08

2366 Solid State High Throughput Screening Microscopy

Ashraf, M.; Mohanan, S.; Sim, B. R.; Tam, A.; Brousseau, D.; Thibault, S.; Corbett, A.; Bub, G.

10.1101/602011 — bioengineering — Posted on 2019-04-08

2367 Continuous theta burst TMS of area MT+ impairs attentive motiontracking.

Chakraborty, A.; Tran, T. T.; Silva, A. E.; Giaschi, D.; Thompson, B.

10.1101/601807 — neuroscience — Posted on 2019-04-08

2368 Quantitative comparison of camera technologies for cost-effective Super-resolution Optical Fluctuation Imaging (SOFI)

Van den Eynde, R.; Sandmeyer, A.; Vandenberg, W.; Duwe, S.; Huebner, W.; Huser, T.; Dedecker, P.; Mueller, M.

10.1101/413179 — biophysics — Posted on 2019-04-08

2369 Splice junction-centric approach to identify translated noncanonical isoforms in the human proteome

Lau, E.; Han, Y.; Williams, D. R.; Shrestha, R.; Wu, J. C.; Lam, M. P. Y.

10.1101/372995 — systems biology — Posted on 2019-04-08

2370 Evolution of simple multicellular life cycles in dynamic environments

Pichugin, Y.; Park, H. J.; Traulsen, A.

10.1101/602250 — evolutionary biology — Posted on 2019-04-08

2371 A three-years assessment of Ixodes ricinus-borne pathogens in a French peri-urban forest

Lejal, E.; Marsot, M.; Chalvet-Monfray, K.; Cosson, J.-F.; Moutailler, S.; Vayssier-Taussat, M.; Pollet, T.

10.1101/597013 — epidemiology — Posted on 2019-04-08

2372 tRNA dissociation from EF-Tu after GTP hydrolysis and Pi release: primary steps and antibiotic inhibition

Warias, M. V.; Grubmuller, H.; Bock, L. V.

10.1101/602383 — biophysics — Posted on 2019-04-08

2373 D-Cycloserine as Adjunct to Brief Computerised CBT for Spider Fear: Effects on Fear, Behaviour, and Cognitive Biases

Kappelmann, N.; Suesse, M.; Schmiedgen, S.; Kaldewaij, R.; Browning, M.; Michael, T.; Rinck, M.; Reinecke, A.

10.1101/602276 — neuroscience — Posted on 2019-04-08

2374 A Theoretical Model of Telomere Length Regulation

Ishii, H.

10.1101/602037 — molecular biology — Posted on 2019-04-08

2375 First genome-wide association study of non-severe malaria in two birth cohorts in Benin.

Milet, J.; Boland, A.; Luisi, P.; Sabbagh, A.; Sadissou, I.; Sonon, P.; Domingo, N.; Palstra, F.; Gineau, L.; Courtin, D.; Massougbodji, A.; Garcia, A.; Deleuze, J.-F.; Perdry, H.

10.1101/483859 — genetics — Posted on 2019-04-08

2376 Evaluating causal associations between previously reported risk factors and epithelial ovarian cancer: a Mendelian randomization analysis

Yarmolinsky, J.; Relton, C. L.; Lophatananon, A.; Muir, K.; Menon, U.; Gentry-Maharaj, A.; Walther, A.; Zheng, J.; Fasching, P.; Zheng, W.; Woo, Y. L.; Chang-Claude, J.; Park, S. K.; Kim, B.-G.; Choi, J.-Y.; Park, B.; Davey Smith, G.; Martin, R.; Lewis, S.

10.1101/472696 — epidemiology — Posted on 2019-04-08

2377 Thermal cycling-hyperthermia in combination with polyphenols, epigallocatechin gallate and chlorogenic acid, exerts synergistic anticancer effect against human pancreatic cancer PANC-1 cells

Lu, C.-H.; Chen, W.-T.; Hsieh, C.-H.; Kuo, Y.-Y.; Chao, C.-Y.

10.1101/548552 — cancer biology — Posted on 2019-04-08

2378 5-HT2B serotonin receptor agonist BW723C86 shapes the macrophage gene profile via AhR and impairs monocyte-to-osteoclast differentiation

Nieto, C.; Rayo, I.; de las Casas-Engel, M.; Izquierdo, E.; Alonso, B.; Vega, M. A.; Corbi, A. L.

10.1101/587709 — immunology — Posted on 2019-04-08

2379 The hidden costs of dietary restriction: implications for its evolutionary and mechanistic origins

McCracken, A. W.; Adams, G.; Hartshorne, L.; Tatar, M.; Simons, M. J. P.

10.1101/533711 — evolutionary biology — Posted on 2019-04-08

2380 Sexual segregation in a highly pagophilic and sexually dimorphic marine predator

Barbraud, C.; Delord, K.; Kato, A.; Bustamante, P.; Cherel, Y.

10.1101/472431 — ecology — Posted on 2019-04-08

2381 Complete assembly of Escherichia coli ST131 genomes using long reads demonstrates antibiotic resistance gene variation within diverse plasmid and chromosomal contexts

Decano, A. G.; Ludden, C.; Feltwell, T.; Judge, K.; Parkhill, J.; Downing, T.

10.1101/558635 — genomics — Posted on 2019-04-08

2382 Gene expression plasticity and frontloading promote thermotolerance in Pocillopora corals

Brener-Raffalli, K.; Vidal-Dupiol, J.; Adjeroud, M.; Rey, O.; Romans, P.; Bonhomme, F.; Pratlong, M.; Haguenauer, A.; Pillot, R.; Feuillassier, L.; Claereboudt, M.; Magalon, H.; Gelin, P.; Pontarotti, P.; Aurelle, D.; Mitta, G.; Toulza, E.

10.1101/398602 — evolutionary biology — Posted on 2019-04-08

2383 Cross-talk between Hippo and Wnt signalling pathways in intestinal crypts: insights from an agent-based model

Ward, D.; Fletcher, A. G.; Homer, M.; Marucci, L.

10.1101/492520 — systems biology — Posted on 2019-04-08

2384 Cholesterol binding to the transmembrane region of a group 2 HA of Influenza virus is essential for virus replication affecting both virus assembly and HA’s fusion activity

Hu, B.; Hoefer, C. T.; Thiele, C.; Veit, M.

10.1101/598953 — cell biology — Posted on 2019-04-08

2385 SOM-based embedding improves efficiency of high-dimensional cytometry data analysis

Kratochvil, M.; Koladiya, A.; Balounova, J.; Novosadova, V.; Sedlacek, R.; Fiser, K.; Vondrasek, J.; Drbal, K.

10.1101/496869 — bioinformatics — Posted on 2019-04-08

2386 Synaptic control of DNA-methylation involves activity-dependent degradation of DNMT3a1 in the nucleus

Bayraktar, G.; Yuanxiang, P.; Gomes, G.; Confettura, A.; Raza, S.; Stork, O.; Tajima, S.; Yilderim, F.; Kreutz, M.

10.1101/602151 — neuroscience — Posted on 2019-04-08

2387 Identification of a basal stem cell subpopulation in the prostate via functional, lineage tracing and single-cell RNA-seq analyses

Wang, X.; Xu, H.; Cheng, C.; Ji, Z.; Zhao, H.; Sheng, Y.; Li, X.; Wang, J.; Shu, Y.; He, Y.; Fan, L.; Dong, B.; Xue, W.; Chua, C. W.; Wu, D.; Gao, W.-Q.; Zhu, H. H.

10.1101/601872 — developmental biology — Posted on 2019-04-08

2388 YAP controls cell migration and invasion through a Rho-GTPase switch

Shah, S. R.; Tippens, N. D.; Park, J.; Mohyeldin, A.; Wang, S.; Vela, G.; Martinez-Gutierrez, J. C.; Margolis, S. S.; Schmidt, S.; Xia, S.; Levchenko, A.; Quinones-Hinojosa, A.

10.1101/602052 — cancer biology — Posted on 2019-04-08

2389 Single-molecule imaging of eukaryotic replisomes reveals compositional plasticity

Lewis, J. S.; Spenkelink, L. M.; Schauer, G. D.; Yurieva, O.; Natarajan, V.; Kaur, G.; Maher, C.; Kay, C.; O'Donnell, M. E.; van Oijen, A. M.

10.1101/602086 — biophysics — Posted on 2019-04-08

2390 Curvature increases permeability of the plasma membrane for ions, water and the anti-cancer drugs cisplatin and gemcitabine

Yesylevskyy, S.; Rivel, T.; ramseyer, c.

10.1101/602177 — biophysics — Posted on 2019-04-08

2391 Fragile X Mental Retardation Protein regulates R-loop formation and prevents global chromosome fragility

Chakraborty, A.; Jenjaroenpun, P.; McCulley, A.; Li, J.; El Hilali, S.; Haarer, B.; Hoffman, E. A.; Belak, A.; Thorland, A.; Hehnly, H.; Chen, C.-l.; Kuznetsov, V.; Feng, W.

10.1101/601906 — genomics — Posted on 2019-04-08

2392 Modelling bistable tumour population dynamics to design effective treatment strategies

Akhmetzhanov, A. R.; Kim, J. W.; Sullivan, R.; Beckman, R. A.; Tamayo, P.; Yeang, C.-H.

10.1101/381418 — cancer biology — Posted on 2019-04-08

2393 Genetic Effects of Welding Fumes on the Development of Respiratory System Diseases

Rana, H. K.; Akhtar, M. R.; Islam, M. B.; Ahmed, M. B.; Lio, P.; Quinn, J. M. W.; Huq, F.; Moni, M. A.

10.1101/480855 — bioinformatics — Posted on 2019-04-08

2394 A human pathogenic bacterium Shigella proliferates in the plant through the adoption of type III effectors for Shigellosis

Jo, S. H.; Lee, J.; Park, E.; Kim, D. W.; Lee, D. H.; Ryu, C. M.; Choi, D.; Park, J. M.

10.1101/292201 — plant biology — Posted on 2019-04-08

2395 An exact transformation for CNN kernel enables accurate sequence motif identification and leads to a potentially full probabilistic interpretation of CNN

Ding, Y.; Li, J.-Y.; Wang, M.; Tu, X.; Gao, G.

10.1101/163220 — bioinformatics — Posted on 2019-04-08

2396 Generation of conditional auxin-inducible degron (AID) cells and tight control of degron-fused proteins using the degradation inhibitor auxinole

Yesbolatova, A.; Natsume, T.; Hayashi, K.-i.; Kanemaki, M. T.

10.1101/530410 — bioengineering — Posted on 2019-04-08

2397 Short Neurorobotics Workshop for High School Students Promotes Competence and Confidence in Computational Neuroscience

Harris, C. A.; Mircic, S.; Reining, Z.; Amorim, M.; Jovic, Đorđe; Guerri, L.; Wallace, W.; Gage, G. J.

10.1101/597609 — scientific communication and education — Posted on 2019-04-07

2398 Androgen-dmrt1 positive feedback programs the rice field eel (Monopterus albus) sex transdifferentiation

Wen, B.; Qu, X.; Pan, L.; Gao, J.; Wu, H.; Wang, Q.

10.1101/595306 — animal behavior and cognition — Posted on 2019-04-07

2399 Unequal interactions between alcohol and nicotine co-consumption: Suppression and enhancement of concurrent drug intake

DeBaker, M. C.; Moen, J. K.; Robinson, J. M.; Wickman, K.; Lee, A. M.

10.1101/601641 — pharmacology and toxicology — Posted on 2019-04-07

2400 Temporal proteomic analysis of BK polyomavirus infection reveals virus-induced G2 arrest and highly effective evasion of innate immune sensing

Caller, L. G.; Davies, C.; Antrobus, R.; Lehner, P.; Weekes, M. P.; Crump, C.

10.1101/601351 — microbiology — Posted on 2019-04-07

2401 Heavy and wet: evaluating the validity and implications of assumptions made when measuring growth efficiency using 18O water

Pold, G.; Domeignoz Horta, L. A.; DeAngelis, K. M.

10.1101/601138 — microbiology — Posted on 2019-04-07

2402 Whole genome phylogenies reflect long-tailed distributions of recombination rates in many bacterial species

Sakoparnig, T.; Field, C.; van Nimwegen, E.

10.1101/601914 — evolutionary biology — Posted on 2019-04-07

2403 Individual variation in phenotypic plasticity of the stress axis

Guindre-Parker, S.; McAdam, A.; van Kesteren, F.; Palme, R.; Boonstra, R.; Boutin, S.; Lane, J.; Dantzer, B.

10.1101/600825 — zoology — Posted on 2019-04-07

2404 Dorsal-to-ventral neocortical expansion is physically primed by ventral streaming of early embryonic preplate neurons

Saito, K.; Okamoto, M.; Watanabe, Y.; Noguchi, N.; Nagasaka, A.; Nishina, Y.; Shinoda, T.; Sakakibara, A.; Miyata, T.

10.1101/601617 — neuroscience — Posted on 2019-04-07

2405 Distinctions among real and apparent respiratory motions in human fMRI data

Power, J.; Silver, B.; Dubin, M.; Martin, A.; Jones, R.

10.1101/601286 — neuroscience — Posted on 2019-04-07

2406 Additive genetic variance for lifetime fitness and the capacity for adaptation in the wild

Kulbba, M. W.; Sheth, S. N.; Pain, R. E.; Eckhart, V. M.; Shaw, R. G.

10.1101/601682 — evolutionary biology — Posted on 2019-04-07

2407 Conformational catalysis of cataract-associated aggregation by interacting intermediates in a human eye lens crystallin

Serebryany, E.; Razban, R.; Shakhnovich, E.

10.1101/601708 — biophysics — Posted on 2019-04-07

2408 Noise-Reducing Negative-Feedback Optogenetic Circuits in Mammalian Cells

Guinn, M. T.; Balazsi, G.

10.1101/601005 — synthetic biology — Posted on 2019-04-07

2409 PBS3 and EPS1 complete salicylic acid biosynthesis from isochorismate in Arabidopsis

Torrens-Spence, M. P.; Bobokalonova, A.; Carballo, V.; Glinkerman, C. M.; Pluskal, T.; Shen, A.; Weng, J.-K.

10.1101/601948 — plant biology — Posted on 2019-04-07

2410 Dopamine depletion affects vocal acoustics and disrupts sensorimotor adaptation in songbirds

Saravanan, V.; Hoffmann, L. A.; Jacob, A. L.; Berman, G. J.; Sober, S. J.

10.1101/600874 — neuroscience — Posted on 2019-04-07

2411 Spectral tilt underlies mathematical problem solving

Randazzo, M. J.; Ezzyat, Y.; Kahana, M. J.

10.1101/601880 — neuroscience — Posted on 2019-04-07

2412 The hourglass organization of the C. elegans connectome

Sabrin, K.; Wei, Y.; van den Heuvel, M.; Dovrolis, C.

10.1101/600999 — neuroscience — Posted on 2019-04-07

2413 Native molecule sequencing by nano-ID reveals synthesis and stability of RNA isoforms

Maier, K. C.; Gressel, S.; Cramer, P.; Schwalb, B.

10.1101/601856 — molecular biology — Posted on 2019-04-07

Lobentanzer, S.; Hanin, G.; Klein, J.; Soreq, H.

10.1101/600932 — molecular biology — Posted on 2019-04-07

2415 Synergistic interactions of quercetin with antibiotics against biofilm associated clinical isolates of Pseudomonas aeruginosa in vitro

Vipin, C.; Mujeeburahiman, M.; Saptami, K.; Arun, A.; Rekha, P.

10.1101/601336 — microbiology — Posted on 2019-04-07

2416 Megaplasmids on the rise: combining sequencing approaches to fully resolve a carbapenemase-encoding plasmid in a proposed novel Pseudomonas species

Botelho, J.; Lood, C.; Partridge, S. R.; van Noort, V.; Lavigne, R.; Grosso, F.; Peixe, L.

10.1101/601898 — microbiology — Posted on 2019-04-07

2417 Grain Protein Content QTLs Identified in a Durum x Wild Emmer Wheat Mapping Population Tested in Five Environments

Fatiukha, A.; Lupo, I.; Lidzbarsky, G.; Klymiuk, V.; Korol, A. B.; Pozniak, C.; Fahima, T.; Krugman, T.

10.1101/601773 — genetics — Posted on 2019-04-07

2418 Unexpected termite inquilines in nests of Constrictotermes cyphergaster (Silvestri, 1901) (Blattodea: Isoptera)

Costa, D. A.; Marins, A.; DeSouza, O.

10.1101/600528 — ecology — Posted on 2019-04-07

2419 From Energy to Cellular Force in the Cellular Potts Model

Rens, E. G.; Edelstein-Keshet, L.

10.1101/601781 — cell biology — Posted on 2019-04-07

2420 SICaRiO: Short Indel Call filteRing with bOosting

Bhuyan, M. S. I.; Pe'er, I.; Rahman, M. S.

10.1101/601450 — bioinformatics — Posted on 2019-04-07

2421 Consistent bacterial responses to land use change across the tropics

Petersen, I. A.; Meyer, K. M.; Bohannan, B. J. M.

10.1101/600924 — ecology — Posted on 2019-04-07

2422 Predicting the partition of behavioral variability in speed perception with naturalistic stimuli

Chin, B. M.; Burge, J.

10.1101/601161 — neuroscience — Posted on 2019-04-07

2423 The limbic circuit for response vigour

Porr, B.; Gomes, P.; Andreassen, T.

10.1101/600973 — neuroscience — Posted on 2019-04-07

Robertson, N. A.; Deary, I. J.; Kirschner, K.; Marioni, R.; Chandra, T.; Lothian Birth Cohort,

10.1101/600759 — bioinformatics — Posted on 2019-04-07

2425 Robust and replicable measurement for prepulse inhibition of the acoustic startle response

Miller, E. A.; Kastner, D. B.; Grzybowski, M. N.; Dwinell, M. R.; Geurts, A. M.; Frank, L. M.

10.1101/601500 — animal behavior and cognition — Posted on 2019-04-07

2426 Genome-wide analyses indirectly implicate miRNA regulatory mechanisms in Obsessive-compulsive Disorder psychopathology

McGregor, N. W.; O'Connell, K. S.; Davis, L.; Mathews, C.; Lochner, C.; Stein, D.

10.1101/601401 — neuroscience — Posted on 2019-04-07

2427 Protracted development of visuo-proprioceptive integration for uni-and bimanual motor coordination

Martel, M.; Ossandon, J. P.; Habets, B.; Heed, T.

10.1101/601435 — neuroscience — Posted on 2019-04-07

2428 Schizophrenia symptoms are inherently heterogeneous: a systematic review of cluster and group-based studies

Habtewold, T. D.; Rodijk, L. H.; Liemburg, E. J.; Sidorenkov, G.; Bruggeman, R.; Alizadeh, B. Z.

10.1101/599498 — neuroscience — Posted on 2019-04-07

2429 Demonstration of a fast and easy sample-to-answer protocol for Mycobacterium tuberculosis diagnosis in point-of-care settings

ali, N.; Bello, G. L.; Rossetti, M. L. R.; Costa, A. D. T.; Krieger, M. A.

10.1101/601476 — molecular biology — Posted on 2019-04-07

2430 Association of milk microbiome in bovine clinical mastitis and their functional implications in cows in Bangladesh

Hoque, M. N.; Istiaq, A.; Clement, R. A.; Sultana, M.; Crandall, K. A.; Siddiki, A. Z.; Hossain, M. A.

10.1101/591982 — molecular biology — Posted on 2019-04-07

2431 Assessing the Structure and Specificity of Polygenic Scores for Psychiatric Disorders in a Population-based Cohort of Older Adults

Gard, A. M. S.; Ware, E. B.; Hyde, L. W.; Schmitz, L.; Faul, J.; Mitchell, C.

10.1101/601609 — genomics — Posted on 2019-04-07

2432 An integrative analysis of GWAS and intermediate molecular trait data reveals common molecular mechanisms supporting genetic similarity between seemingly unrelated complex traits

Gu, J.; Fuller, C.; Zheng, J.; Li, H.

10.1101/601229 — genetics — Posted on 2019-04-07

2433 Phylogenetic synecdoche demonstrates optimality of subsampling and improves recovery of the Blaberoidea phylogeny

Evangelista, D. A.; Simon, S.; Wilson, M. M.; Kohli, M. K.; Ware, J. L.; Kawahara, A. Y.; Wipfler, B.; Bethoux, O.; Grandcolas, P.; Legendre, F.

10.1101/601237 — evolutionary biology — Posted on 2019-04-07

2434 Generation of human hepatic progenitor cells with regenerative and metabolic capacities from primary hepatocytes

Katsuda, T.; Matsuzaki, J.; Yamaguchi, T.; Yamada, Y.; Hosaka, K.; Takeuchi, A.; Saito, Y.; Ochiya, T.

10.1101/601922 — cell biology — Posted on 2019-04-07

2435 Object Colours, Material Properties and Animal Signals

Wilkins, L.; Osorio, D.

10.1101/601625 — animal behavior and cognition — Posted on 2019-04-07

2436 Heterologous Cas9 and non-homologous end joining as a Potentially Organism-Agnostic Knockout (POAK) system in bacteria

Plant, I. N.

10.1101/601971 — synthetic biology — Posted on 2019-04-07

2437 Praziquantel activates a schistosome transient receptor potential channel

Park, S. K.; McCusker, P.; Dosa, P. I.; Chan, J. D.; Marchant, J. S.

10.1101/600791 — pharmacology and toxicology — Posted on 2019-04-07

2438 Targeting age-related differences in brain and cognition with multimodal imaging and connectome topography profiling

Lowe, A.; Paquola, C.; Vos de Wael, R.; Girn, M.; Lariviere, S.; Tavakol, S.; Caldairou, B.; Royer, J.; Schrader, D.; Bernasconi, A.; Bernasconi, N.; Spreng, R. N.; Bernhardt, B.

10.1101/601146 — neuroscience — Posted on 2019-04-07

2439 Destabilization of the tumor-inducing plasmid from an octopine-type Agrobacterium tumefaciens lineage drives a large deletion in the co-resident At megaplasmid

Barton, I. S.; Platt, T. G.; Rusch, D. B.; Fuqua, C.

10.1101/600809 — microbiology — Posted on 2019-04-07

2440 Peptidoglycan layer and disruption processes in Bacillus subtilis cells visualized using quick-freeze, deep-etch electron microscopy

Tulum, I.; Tahara, Y. O.; Miyata, M.

10.1101/600171 — microbiology — Posted on 2019-04-07

2441 IRF5 promotes intestinal inflammation by guiding monocyte differentiation towards a pathogenic CD11c+ macrophage phenotype

Corbin, A. L.; Gomez-Vazquez, M.; Khoyratty, T. E.; Berthold, D. L.; Almuttaqi, H.; Attar, M.; Arnold, I. C.; Powrie, F. M.; Sansom, S. N.; Udalova, I. A.

10.1101/601963 — immunology — Posted on 2019-04-07

2442 Chromatin-lamin B1 interaction promotes genomic compartmentalization and constrains chromatin dynamics

Chang, L.; Li, M.; Shao, S.; Xue, B.; Hou, Y.; Zhang, Y.; Li, R.; Li, C.; Sun, Y.

10.1101/601849 — genomics — Posted on 2019-04-07

2443 Systematics, biogeography and diversification of Scytalopus tapaculos (Rhinocryptidae), an enigmatic radiation of Neotropical montane birds

Cadena, D.; Cuervo, A.; Cespedes, L. N.; Bravo, G. A.; Krabbe, N.; Schulenberg, T. S.; Derryberry, G. E.; Silveira, L. F.; Derryberry, E. P.; Brumfield, R. T.; Fjeldsa, J.

10.1101/600775 — evolutionary biology — Posted on 2019-04-07

2444 xml2jupyter: Mapping parameters between XML and Jupyter widgets

Heiland, R.; Mishler, D.; Zhang, T.; Bower, E.; Macklin, P.

10.1101/601211 — bioinformatics — Posted on 2019-04-07

2445 Exploring genetic interaction manifolds constructed from rich phenotypes

Norman, T. M.; Horlbeck, M. A.; Replogle, J. M.; Ge, A. Y.; Xu, A.; Jost, M.; Gilbert, L. A.; Weissman, J. S.

10.1101/601096 — genomics — Posted on 2019-04-07

2446 Influenza A matrix protein M1 induces lipid membrane deformation via protein multimerization

Dahmani, I.; Ludwig, K.; Chiantia, S.

10.1101/565952 — biophysics — Posted on 2019-04-07

2447 Improving the accuracy of single turnover active fluorometry (STAF) for the estimation of phytoplankton primary productivity (PhytoPP)

Boatman, T. G.; Geider, R. J.; Oxborough, K.

10.1101/583591 — plant biology — Posted on 2019-04-07

2448 Updated MS2PIP web server delivers fast and accurate MS2 peak intensity prediction for multiple fragmentation methods, instruments and labeling techniques

Gabriels, R.; Martens, L.; Degroeve, S.

10.1101/544965 — bioinformatics — Posted on 2019-04-07

2449 Cognitive self-regulation influences pain-related physiology

Matthewson, G.; Woo, C.-W.; Reddan, M. C.; Wager, T. D.

10.1101/361519 — neuroscience — Posted on 2019-04-07

2450 Circadian control of the secretory pathway is a central mechanism in tissue homeostasis

Chang, J.; Garva, R.; Pickard, A.; Yeung, C.-Y. C.; Mallikarjun, V.; Swift, J.; Holmes, D. F.; Calverley, B.; Lu, Y.; Adamson, A.; Raymond-Hayling, H.; Jensen, O.; Shearer, T.; Meng, Q. J.; Kadler, K. E.

10.1101/304014 — cell biology — Posted on 2019-04-07

2451 The Influence of Molecular Reach and Diffusivity on the Efficacy of Membrane-Confined Reactions

Zhang, Y.; Clemens, L.; Goyette, J.; Allard, J.; Dushek, O.; Isaacson, S. A.

10.1101/439430 — biophysics — Posted on 2019-04-07

2452 SOLart: a structure-based method to predict protein solubility and aggregation

Hou, Q.; Kwasigroch, J. M.; Rooman, M.; Pucci, F.

10.1101/600734 — bioinformatics — Posted on 2019-04-07

2453 Accelerated evolution of oligodendrocytes in human brain

Berto, S.; Mendizabal, I.; Usui, N.; Toriumi, K.; Chatterjee, P.; Douglas, C.; Tamminga, C.; Preuss, T.; Yi, S.; Konopka, G.

10.1101/601062 — evolutionary biology — Posted on 2019-04-07

2454 The fungal gene cluster for biosynthesis of the antibacterial agent viriditoxin

Urquhart, A. S.; Hu, J.; Chooi, Y.-H.; Idnurm, A.

10.1101/601716 — microbiology — Posted on 2019-04-07

2455 Alternative Polyadenylation Modifies Target Sites of MicroRNAs with Clinical Potential for Breast Cancer Progression

Kim, S.; Bai, Y.; Diergaarde, B.; Tseng, G. C.; Park, H. J.

10.1101/601518 — bioinformatics — Posted on 2019-04-07

2456 Pooled-parent exome sequencing to prioritise de novo variants in genetic disease

Dashnow, H.; Bell, K. M.; Stark, Z.; Tan, T. Y.; White, S. M.; Oshlack, A.

10.1101/601740 — bioinformatics — Posted on 2019-04-07

2457 Genomic and epigenomic mapping of leptin-responsive neuronal populations involved in body weight regulation

Inoue, F.; Eckalbar, W.; Wang, Y.; Murphy, K. K.; Matharu, N.; Vaisse, C.; Ahituv, N.

10.1101/601070 — genomics — Posted on 2019-04-07

2458 Imaging chromatin interactions at sub-kilobase resolution Via Tn5-FISH

Zhang, X.; Niu, J.; Li, G.; Dai, Q.; Jin, D.; Gao, J.; Zhang, M. Q.

10.1101/601690 — cell biology — Posted on 2019-04-07

2459 In silico analysis of coding SNPs and 3′-UTR associated miRNAs in DCAF17 gene that may affect the regulation and pathogenesis of Woodhouse-Sakati Syndrome

abdelmoneim, a. h.; Elrashied, A. M.; Mohammed, A. I.; Mirghani, S. A.; Osman, R. E.; Gadim, E. O.; Salih, M. A.

10.1101/601310 — bioinformatics — Posted on 2019-04-07

2460 Icosahedral viruses defined by their positively charged domains: a signature for viral identity and capsid assembly strategy

Requiao, R. D.; Carneiro, R. L.; Moreira, M. H.; Ribeiro-Alves, M.; Rossetto, S.; Palhano, F.; Domitrovic, T.

10.1101/600981 — bioinformatics — Posted on 2019-04-07

2461 Microbiota differences of the comb jelly Mnemiopsis leidyi in native and invasive sub-populations

Jaspers, C.; Weiland-Braeuer, N.; Fischer, M.; Kuenzel, S.; Schmitz-Streit, R. A.; Reusch, T. B. H.

10.1101/601419 — microbiology — Posted on 2019-04-07

2462 Sortase-assembled pili promote extracellular electron transfer and iron acquisition in Enterococcus faecalis biofilm

Lam, L. N.; Wong, J. J.; Matysik, A.; Paxman, J. J.; Chong, K. K. L.; Low, P. M.; Chua, Z. S.; Heras, B.; Marsili, E.; Kline, K. A.

10.1101/601666 — microbiology — Posted on 2019-04-07

2463 3ʹ-UTR shortening disrupts ceRNA crosstalk of housekeeping genes resulting in subtype-specific breast cancer development

Zhenjiang, F.; Kim, S.; Diergaarde, B.; Park, H. J.

10.1101/601526 — cancer biology — Posted on 2019-04-07

2464 Simulation-Based protein engineering of R. erythropolis NADH-FMN Oxidoreductase

Fallahzadeh, R.; Bambai, B.; KAmali, N.; Esfahani, K.; Akhavan Sepahy, A.

10.1101/601252 — bioinformatics — Posted on 2019-04-07

2465 Investigating Biomechanical Properties of A. tortilis as Related to their Habitat

Faris, A. O.; Altoum, R.; Salameh, I.; Salameh, M.; Al-Mohannadi, S.; Mahmoud, A.

10.1101/601534 — plant biology — Posted on 2019-04-07

2466 Bacillus subtilis ALBA01 can mitigate onion pink root symptoms caused by Setophoma terrestris

Sayago, P.; Juncosa, F.; Albarracin Orio, A.; Luna, D. F.; Molina, G.; Lafi, J.; Ducasse, D. A. A.

10.1101/601633 — microbiology — Posted on 2019-04-07

2467 Inhibition of Stearoyl-CoA desaturase suppresses follicular help T and germinal center B cell responses

Son, Y.; Cheon, I. S.; Goplen, N.; Dent, A.; Sun, J.

10.1101/601021 — immunology — Posted on 2019-04-07

2468 Is amphistomy an adaptation to high light? Optimality models of stomatal traits along light gradients

Muir, C.

10.1101/601377 — plant biology — Posted on 2019-04-07

2469 Seed treatment with chitosan synergizes plant growth promoting ability of Pseudomonas aeruginosa-P17 in sorghum (Sorhum bicolor L.)

G, P. K.; Desai, S.; Moerschbacher, B.; El Gueddari, N. E.

10.1101/601328 — microbiology — Posted on 2019-04-07

2470 Translation and Transforming Activity of a Circular RNA from Human Papillomavirus

Zhao, J.; Lee, E. E.; Kim, J.; Chamseddin, B.; Yang, R.; Xie, Y.; Zhan, X.; Wang, R.

10.1101/600056 — molecular biology — Posted on 2019-04-07

2471 Quantifying the contribution of sequence variants with regulatory and evolutionary significance to 34 bovine complex traits

Xiang, R.; Berg, I. V.; MacLeod, I.; Hayes, B.; Prowse-Wilkins, C.; Wang, M.; Bolormaa, S.; Liu, Z.; Rochfort, S.; Reich, C.; Mason, B.; Vander Jagt, C.; Daetwyler, H.; Lund, M.; Chamberlain, A.; Goddard, M.

10.1101/601658 — genomics — Posted on 2019-04-07

2472 Mosquito and primate ecology predict human risk of yellow fever virus spillover in Brazil

Childs, M. L.; Nova, N.; Colvin, J.; Mordecai, E. A.

10.1101/523704 — ecology — Posted on 2019-04-07

2473 Whole cell response to receptor stimulation involves many deep and distributed subcellular processes

Hansen, J.; Yadaw, A. S.; Siddiq, M. M.; Tolentino, R.; Rabinovich, V.; Jain, M.; Liu, T.; Li, H.; Goldfarb, J.; Iyengar, R.

10.1101/462200 — cell biology — Posted on 2019-04-07

2474 Precise memory is predicted by learning-induced sensory system neurophysiological plasticity

Rotondo, E. K.; Bieszczad, K. M.

10.1101/600866 — neuroscience — Posted on 2019-04-06

2475 Differential Inhibition of E-S Potentiation and Long-term Potentiation by Cell-derived and Arctic Amyloid Beta

Orr, A. L.; Clark, J. K.; Madison, D. V.

10.1101/601492 — neuroscience — Posted on 2019-04-06

2476 Aggression Subtypes Relate to Distinct Resting State Functional Connectivity in Disruptive Children and Adolescents

Werhahn, J. E.; Mohl, S.; Willinger, D.; Smigielski, L.; Roth, A.; Hofstetter, C.; Staempfli, P.; Haeberling, I.; Naaijen, J.; Mulder, L. M.; Glennon, J. C.; Hoekstra, P. J.; Dietrich, A.; Kleine Deters, R.; Aggensteiner, P. M.; Holz, N. E.; Baumeister, S.; Banaschewski, T.; Saam, M. C.; Schulze, U. M. E.; Lythgoe, D. J.; Sethi, A.; Craig, M.; Mastroianni, M.; Sagar-Ouriaghli, I.; Santosh, P. J.; Rosa, M.; Bargallo, N.; Castro-Fornieles, J.; Aragno, C.; Penzol, M. J.; Franke, B.; Zwiers, M. P.; Buitelaar, J. K.; Walitza, S.; Brandeis, D.

10.1101/462382 — neuroscience — Posted on 2019-04-06

2477 Quantitative measurements of chromatin modification dynamics during zygotic genome activation

Sato, Y.; Hilbert, L.; Oda, H.; Wan, Y.; Heddleston, J. M.; Chew, T.-L.; Zaburdaev, V.; Keller, P.; Lionnet, T.; Vastenhouw, N.; Kimura, H.

10.1101/601393 — cell biology — Posted on 2019-04-06

2478 Pan-Cancer Exploration of mRNA Mediated Dysregulated Pathways in the Cancer Genomics Cloud

Linan, M.; Wang, J.; Dinu, V.

10.1101/599225 — bioinformatics — Posted on 2019-04-06

2479 Multiplexed Analysis of the Secretin-like GPCR-RAMP Interactome

Lorenzen, E.; Dodig-Crnkovic, T.; Kotliar, I. B.; Pin, E.; Ceraudo, E.; Vaughan, R. D.; Uhlen, M.; Huber, T.; Schwenk, J. M.; Sakmar, T. P.

10.1101/597690 — biochemistry — Posted on 2019-04-06

2480 Cryo-EM Structures of Four Polymorphic TDP-43 Amyloid Cores

Cao, Q.; Boyer, D. R.; Sawaya, M. R.; Ge, P.; Eisenberg, D. S.

10.1101/601120 — biochemistry — Posted on 2019-04-06

2481 CNTNAP2 is targeted to endosomes by the polarity protein Par3

Gao, R.; Pratt, C.; Yoon, S.; Martin-de-Saavedra, M. D.; Forrest, M.; Penzes, P.

10.1101/601575 — neuroscience — Posted on 2019-04-06

2482 The proton-sensing GPR4 receptor regulates paracellular gap formation and permeability of vascular endothelial cells

Krewson, E. A.; Sanderlin, E. J.; Marie, M. A.; Velcicky, J.; Loetscher, P.; Yang, L. V.

10.1101/601088 — cell biology — Posted on 2019-04-06

2483 Feature-specific prediction errors for visual mismatch

Stefanics, G.; Stephan, K. E.; Heinzle, J.

10.1101/447243 — neuroscience — Posted on 2019-04-06

2484 Intracellular anti-leishmanial effect of Spergulin-A, a triterpenoid saponin of Glinus oppositifolius

Banerjee, S.; Mukherjee, N.; Gajbhiye, R. L.; Jaisankar, P.; Datta, S.; Das Saha, K.

10.1101/458653 — microbiology — Posted on 2019-04-06

2485 CRISPR-Cas9 screening of KSHV-transformed cells identifies XPO1 as a vulnerable target of cancer cells

Gruffaz, M.; Yuan, H.; Meng, W.; Liu, H.; Bae, S.; Kim, J. S.; Lu, C.; Huang, Y.; Gao, S.-J.

10.1101/601369 — cancer biology — Posted on 2019-04-06

2486 Cancer cells resist mechanical destruction in the circulation via RhoA-myosin II axis

Moose, D. L.; Krog, B. L.; Zhao, L.; Kim, T.-H.; Williams-Perez, S.; Burke, G.; Rhodes, L.; Vanneste, M.; Breheny, P.; Milhem, M.; Stipp, C. S.; Rowat, A. C.; Henry, M. D.

10.1101/601039 — cancer biology — Posted on 2019-04-06

2487 A Thermodynamic Limit on the Role of Self-Propulsion in Enhanced Enzyme Diffusion

Feng, M.; Gilson, M. K.

10.1101/451682 — biophysics — Posted on 2019-04-06

2488 The Bayesian-Laplacian Brain

Zeki, S.; Chen, O. Y.

10.1101/094516 — neuroscience — Posted on 2019-04-06

2489 Interplay Between Short-range Attraction and Long-range Repulsion Controls Reentrant Liquid Condensation of Ribonucleoprotein-RNA Complexes

Alshareedah, I.; Kaur, T.; Ngo, J.; Seppala, H.; Djomnang Kounatse, L.-A.; Wang, W.; Moosa, M. M.; Banerjee, P. R.

10.1101/600601 — biophysics — Posted on 2019-04-06

2490 Colocalization features for classification of tumors using desorption electrospray ionization mass spectrometry imaging

Inglese, P.; dos Santos Correia, G.; Pruski, P.; Glen, R. C.; Takats, Z.

10.1101/440057 — bioinformatics — Posted on 2019-04-06

2491 Moving beyond P values: Everyday data analysis with estimation plots

Ho, J.; Tumkaya, T.; Aryal, S.; Choi, H.; Claridge-Chang, A.

10.1101/377978 — bioinformatics — Posted on 2019-04-06

2492 Genetic analyses led to the discovery of a super-active mutant of the RNA polymerase I

Darriere, T.; Pilsl, M.; Sarthou, M.-K.; Chauvier, A.; Genty, T.; Audibert, S.; Dez, C.; Leger-Silvestre, I.; Normand, C.; Henras, A. K.; Kwapisz, M.; Calvo, O.; Fernandez-Tornero, C.; Tschochner, H.; Gadal, O.

10.1101/307199 — molecular biology — Posted on 2019-04-06

2493 Optimization and validation of a quadruplex real-time PCR assay for the diagnosis of diphtheria

Badell, E.; Guillot, S.; Tulliez, M.; Pascal, M.; Panunzi, L. G.; Rose, S.; Litt, D.; Fry, N. K.; Brisse, S.

10.1101/600270 — microbiology — Posted on 2019-04-06

2494 A New European Species of The Opportunistic Pathogenic Genus Saksenaea - S. dorisiae Sp. Nov.

Labuda, R.; Bernreiter, A.; Hochenauer, D.; Schüller, C.; Kubatova, A.; Strauss, J.; Wagner, M.

10.1101/597955 — microbiology — Posted on 2019-04-06

2495 Murine cytomegalovirus infection of melanoma lesions delays tumor growth by recruiting and re-polarizing monocytic phagocytes in the tumor

Wilski, N. A.; Del Casale, C.; Purwin, T. J.; Aplin, A. E.; Snyder, C. M.

10.1101/597948 — immunology — Posted on 2019-04-06

2496 Drosophila ribosomal protein S5b is essential for oogenesis and interacts with distinct RNAs

Kong, J.; Han, H.; Bergalet, J.; Benoit Bouvrette, L. P.; Hernandez, G.; Moon, N. S.; Vali, H.; Lecuyer, E.; Lasko, P.

10.1101/600502 — developmental biology — Posted on 2019-04-06

2497 Deciphering the protein dynamics and molecular determinants of iPSC-derived neurons.

Varderidou-Minasian, S.; Schätzle, P.; Hoogenraad, C.; Pasterkamp, R. J.; Altelaar, M.

10.1101/599415 — neuroscience — Posted on 2019-04-06

2498 Seasonal Change of Microbial Diversity and Its Relation with Soil Chemical Properties in Orchard

Luo, X.; Wang, M.; Hu, G.; Weng, B.

10.1101/600668 — microbiology — Posted on 2019-04-06

2499 Isolation of persisters enabled by ss-lactam-induced filamentation reveals their single-cell awakening characteristics

Windels, E. M.; Ben Meriem, Z.; Zahir, T.; Verstrepen, K. J.; Hersen, P.; Van den Bergh, B.; Michiels, J.

10.1101/600700 — microbiology — Posted on 2019-04-06

2500 The Role of CD147 in Leukocyte Aggregation in Liver Injury

Main, N.; Yee, C.; Terry, A.; Stevanovski, I.; Maczurek, A.; Morgan, A. J.; Calabro, S.; Potter, A. J.; Iemma, T. L.; Bowen, D. G.; Ahlenstiel, G.; Warner, F. J.; McCaughan, G. W.; McLennan, S. V.; Shackel, N. A.

10.1101/600676 — immunology — Posted on 2019-04-06

2501 Cholera in Internally Displaced Persons Camps in Borno State--Nigeria, 2017: A qualitative study of the multi-sectorial emergency response to stop the spread of the outbreak

Ngwa, M. C.; Wondimagegnehu, A.; Okudo, I.; Owili, C.; Ugochukwu, U.; Peter, C.; Devaux, I.; Pezzoli, L.; Ihekweazu, C.; Sack, D. A.

10.1101/599787 — epidemiology — Posted on 2019-04-06

2502 Inhibiting TG2 sensitize lung cancer to radiotherapy through interfering TOPOIIα-mediated DNA repair

Lei, X.; Liu, Z.; Cao, K.; Chen, Y.; Cai, J.; Gao, F.; Yang, Y.

10.1101/597112 — cancer biology — Posted on 2019-04-06

2503 Protein structure determination using Riemannian approach

Wei, X.; Li, Z.; Li, S.; Peng, X.; Zhao, Q.

10.1101/599761 — bioinformatics — Posted on 2019-04-06

2504 A two-enzyme adaptive unit in bacterial folate metabolism

Schober, A. F.; Mathis, A. D.; Ingle, C.; Park, J. O.; Chen, L.; Rabinowitz, J. D.; Junier, I.; Rivoire, O.; Reynolds, K. A.

10.1101/120006 — systems biology — Posted on 2019-04-06

2505 A human pathogenic bacterium Shigella proliferates in the plant through the adoption of type III effectors for Shigellosis

Jo, S. H.; Lee, J.; Park, E.; Kim, D. W.; Lee, D. H.; Ryu, C. M.; Choi, D.; Park, J. M.

10.1101/292201 — plant biology — Posted on 2019-04-06

2506 Domain-specific quantification of prion protein in cerebrospinal fluid by targeted mass spectrometry

Minikel, E. V.; Kuhn, E.; Cocco, A. R.; Vallabh, S. M.; Hartigan, C. R.; Reidenbach, A. G.; Safar, J. G.; Raymond, G. J.; McCarthy, M. D.; O'Keefe, R.; Llorens, F.; Zerr, I.; Capellari, S.; Parchi, P.; Schreiber, S. L.; Carr, S. A.

10.1101/591487 — neuroscience — Posted on 2019-04-05

2507 Separate lanes for math and reading in the white matter highways of the human brain

Grotheer, M.; Zhen, Z.; Lerma-Usabiaga, G.; Grill-Spector, K.

10.1101/420216 — neuroscience — Posted on 2019-04-05

2508 A biochemical mechanism for time-encoding memory formation within individual synapses of Purkinje cells

Mandwal, A.; Orlandi, J.; Simon, C.; Davidsen, J.

10.1101/596148 — neuroscience — Posted on 2019-04-05

2509 Measuring shared responses across subjects using intersubject correlation

Nastase, S. A.; Gazzola, V.; Hasson, U.; Keysers, C.

10.1101/600114 — neuroscience — Posted on 2019-04-05

2510 What, if anything, is the true neurophysiological significance of rotational dynamics?

Lebedev, M. A.; Adell Mill, N.; Armengol Urpi, N.; Cervera, M. R.; Nicolelis, M. A.

10.1101/597419 — neuroscience — Posted on 2019-04-05

2511 Individual tree-crown detection in RGB imagery using semi-supervised deep learning neural networks

Weinstein, B.; Marconi, S.; Bohlman, S.; Zare, A.; White, E.

10.1101/532952 — ecology — Posted on 2019-04-05

2512 Rapid discovery of drug target engagement by isothermal shift assay

Webb, K. J.; Ball, K. A.; Coleman, S. J.; Jacobsen, J.; Stowell, M.; Old, W. M.

10.1101/584656 — pharmacology and toxicology — Posted on 2019-04-05

2513 Exome sequencing identifies high impact trait-associated alleles enriched in Finns

Locke, A. E.; Meltz Steinberg, K.; Chiang, C. W.; Service, S.; Havulinna, A.; Stell, L.; Pirinen, M.; Abel, H. J.; Chiang, C.; Fulton, R. S.; Jackson, A. U.; Kang, C. J.; Kanchi, K.; Koboldt, D. C.; Larson, D.; Nelson, J.; Nicholas, T. J.; Pietila, A.; Ramensky, V.; Ray, D.; Scott, L. J.; Stringham, H. M.; Vangipurapu, J.; Welch, R.; Yajnik, P.; Yin, X.; Eriksson, J.; Ala-Korpela, M.; Jarvelin, M.-R.; Manniko, M.; Laivouri, H.; Project, F.; Dutcher, S. K.; Stitziel, N. O.; Wilson, R. K.; Hall, I. M.; Sabatti, C.; Palotie, A.; Salomaa, V.; Laakso, M.; Ripatti, S.; Boehnke, M.; Freimer, N. B.

10.1101/464255 — genomics — Posted on 2019-04-05

2514 Stochastic gene expression is optimized to drive developmental self organization

Giri, R.; Papadopoulos, D. K.; Posadas, D. M.; Potluri, H.; Tomancak, P.; Mani, M.; Carthew, R.

10.1101/546911 — developmental biology — Posted on 2019-04-05

2515 High-throughput quantitative detection of basal autophagy and autophagic flux using image cytometry

Senthilkumar, G.; Skiba, J. H.; Kimple, R. J.

10.1101/590513 — cell biology — Posted on 2019-04-05

2516 Biofilm-associated Mycobacterium abscessus cells have altered antibiotic tolerance and surface glycolipids in Artificial Cystic Fibrosis Sputum Media

Hunt Serracin, A. C.; Parks, B. J.; Boll, J.; Boutte, C.

10.1101/479923 — microbiology — Posted on 2019-04-05

2517 The ecological cocktail party: Measuring brain activity during an auditory oddball task with background noise

Scanlon, J. E. M.; Cormier, D. L.; Townsend, K. A.; Kuziek, J. W. P.; Mathewson, K. E.

10.1101/371435 — neuroscience — Posted on 2019-04-05

2518 Climatic stability and resource availability explains dung beetles (Scarabaeinae)

Medina, A. M.

10.1101/402537 — zoology — Posted on 2019-04-05

2519 Mechanistic origin of cell-size control and homeostasis in bacteria

Si, F.; Le Treut, G.; Sauls, J. T.; Vadia, S.; Levin, P. A.; Jun, S.

10.1101/478818 — systems biology — Posted on 2019-04-05

2520 Differences in GluN2B-containing NMDA receptors result in opposite long-term plasticity and dopaminergic modulation at ipsilateral vs. contralateral cortico-striatal synapses

Li, W.; Pozzo-Miller, L.

10.1101/599969 — neuroscience — Posted on 2019-04-05

2521 Investigating the Osteoinductive Potential of a Decellularized Xenograft Bone Substitute

Bracey, D. N.; Jinnah, A. H.; Willey, J. S.; Seyler, T. M.; Hutchinson, I. D.; Whitlock, P. W.; Smith, T. L.; Danelson, K. A.; Emory, C. L.; Kerr, B. A.

10.1101/419101 — bioengineering — Posted on 2019-04-05

2522 Understanding visual attention with RAGNAROC: A Reflexive Attention Gradient through Neural AttRactOr Competition

Wyble, B.; Callahan-Flintoft, C.; Chen, H.; Marinov, T.; Sarkar, A.; Bowman, H.

10.1101/406124 — neuroscience — Posted on 2019-04-05

2523 Identifying and classifying shared selective sweeps from multilocus data

Harris, A. M.; DeGiorgio, M.

10.1101/446005 — evolutionary biology — Posted on 2019-04-05

2524 A Bayesian Approach to Restricted Latent Class Models for Scientifically-Structured Clustering of Multivariate Binary Outcomes

Wu, Z.; Casciola-Rosen, L.; Rosen, A.; Zeger, S. L.

10.1101/400192 — bioinformatics — Posted on 2019-04-05

2525 Optical induction of autophagy via Transcription factor EB (TFEB) reduces pathological tau in neurons

Binder, J. L.; Deretic, V.; Weick, J.; Bhaskar, K.

10.1101/600908 — neuroscience — Posted on 2019-04-05

2526 Composition and structure of synaptic ectosomes exporting antigen receptor linked to functional CD40 ligand from helper T-cells

10.1101/600551 — immunology — Posted on 2019-04-05

2527 Congruence of location-specific transcriptional programs in intestinal organoids during long-term culture

van der Hee, B.; Madsen, O.; Smidt, H.; Wells, J. M.

10.1101/600940 — cell biology — Posted on 2019-04-05

2528 Identification and characterization of Gypsophila paniculata color morphs in Sleeping Bear Dunes National Lakeshore, MI, USA.

Yang, M. L.; Rice, E.; Leimbach-Mas, H.; Partridge, C. G.

10.1101/201350 — plant biology — Posted on 2019-04-05

2529 Transcriptional analysis defines TCR and cytokine-stimulated MAIT cells as rapid polyfunctional effector T cells that can coordinate the immune response

Lamichhane, R.; Schneider, M.; de la Harpe, S. M.; Harrop, T. W. R.; Hannaway, R. F.; Dearden, P.; Kirman, J. R.; Tyndall, J. D. A.; Vernall, A. J.; Ussher, J. E.

10.1101/600189 — immunology — Posted on 2019-04-05

2530 Apoptosis in the fetal testis eliminates developmentally defective germ cell clones

Nguyen, D. H.; Laird, D. J.

10.1101/601013 — developmental biology — Posted on 2019-04-05

2531 A distinct cardiopharyngeal mesoderm genetic hierarchy establishes antero-posterior patterning of esophagus striated muscle

Comai, G.; Heude, E.; Mella, S.; Paisant, S.; Pala, F.; Gallardo, M.; Kardon, G.; Gopalakrishnan, S.; Tajbakhsh, S.

10.1101/600841 — developmental biology — Posted on 2019-04-05

2532 Goal congruency dominates reward value in accounting for behavioral and neural correlates of value-based decision-making

Froemer, R.; Dean Wolf, C. K.; Shenhav, A.

10.1101/600148 — neuroscience — Posted on 2019-04-05

2533 The piRNA Response to Retroviral Invasion of the Koala Genome

Yu, T.; Koppetsch, B.; Chappell, K.; Pagliarani, S.; Johnston, S.; Weng, Z.; Theurkauf, W.

10.1101/599852 — genetics — Posted on 2019-04-05

2534 NOTCH1 signaling establishes the medullary thymic epithelial cell progenitor pool during mouse fetal development

Li, J.; Gordon, J.; Chen, E. L. Y.; Wu, L.; Zuniga-Pflucker, J. C.; Manley, N.

10.1101/600817 — developmental biology — Posted on 2019-04-05

2535 Separate domains of G3BP promote efficient clustering of alphavirus replication complexes and recruitment of the translation initiation machinery

Gotte, B.; Panas, M. D.; Hellstrom, K.; Liu, L.; Samreen, B.; Larsson, O.; Ahola, T.; McInerney, G. M.

10.1101/600338 — microbiology — Posted on 2019-04-05

2536 A new immunotherapeutic concept for pancreatic cancer using childhood vaccine recall antigens and Listeria

10.1101/600106 — immunology — Posted on 2019-04-05

2537 ASSESSING CONFIDENCE IN THE RESULTS OF NETWORK META-ANALYSIS (CINEMA)

Nikolakopoulou, A.; Higgins, J. P.; Papakonstantinou, T.; Chaimani, A.; Del Giovane, C.; Egger, M.; Salanti, G.

10.1101/597047 — epidemiology — Posted on 2019-04-05

2538 Linking molecular pathways and large-scale computational modeling to assess candidate disease mechanisms and pharmacodynamics in Alzheimer's disease

Stefanovski, L.; Triebkorn, P.; Spiegler, A.; Diaz-Cortes, M.-A.; Solodkin, A.; Jirsa, V.; McIntosh, R.; Ritter, P.; The Alzheimer's Disease Neuroimaging Initiative,

10.1101/600205 — neuroscience — Posted on 2019-04-05

2539 Resting state cerebral networks in mouse lemur primates: from multilevel validation to comparison with humans

Garin, C. M.; Nadkarni, N. A.; Landeau, B.; Chetelat, G.; Picq, J.-L.; Bougacha, S.; Dhenain, M.

10.1101/599423 — neuroscience — Posted on 2019-04-05

2540 Gene-level heritability analysis explains the polygenic architecture of cancer

Fanfani, V.; Citi, L.; Harris, A. L.; Pezzella, F.; Stracquadanio, G.

10.1101/599753 — genetics — Posted on 2019-04-05

2541 Evolutionary contingency’s impact on laboratory evolution of Escherichia coli under fluctuating environments

Pechuan, X.; Biro, D.; Lambros, M.; Bergman, A.

10.1101/598995 — evolutionary biology — Posted on 2019-04-05

2542 Associatively-mediated suppression of corticospinal excitability: A transcranial magnetic stimulation (TMS) study

Seet, M. S.; Livesey, E. J.; Harris, J. A.

10.1101/600163 — neuroscience — Posted on 2019-04-05

2543 Correlates of resting and exertional dyspnea among older adults with obstructive lung disease: a cross-sectional analysis of the Canadian Longitudinal Study on Aging

Good, J.; Stickland, M.; Dogra, S.

10.1101/596114 — epidemiology — Posted on 2019-04-05

2544 Identifying risk factors involved in the common versus specific liabilities to substance abuse: A genetically informed approach

Iob, E.; Schoeler, T.; Cecil, C. M.; Walton, E.; McQuillin, A.; Pingault, J.-B.

10.1101/595728 — epidemiology — Posted on 2019-04-05

2545 Solving the first novel protein structure by 3D micro-crystal electron diffraction

Xu, H.; Lebrette, H.; Clabbers, M. T. B.; Zhao, J.; Griese, J.; Zou, X.; Hogbom, M.

10.1101/600387 — molecular biology — Posted on 2019-04-05

2546 Deep transcriptome sequencing of subgenual anterior cingulate cortex reveals disorder-specific expression changes in major psychiatric disorders

Akula, N.; Marenco, S.; Johnson, K.; Feng, N.; Cross, J.; England, B.; Detera-Wadleigh, S.; Xu, Q.; Auluck, P. K.; Ahn, K.; Kramer, R.; Apud, J.; Harris, B. T.; Rhodes, H. C.; Lipska, B. K.; McMahon, F. J.

10.1101/598649 — genomics — Posted on 2019-04-05

2547 A collection of yeast cellular electron cryotomography data

Gan, L.; Ng, C. T.; Chen, C.; Cai, S.

10.1101/594432 — cell biology — Posted on 2019-04-05

2548 DeeplyTough: Learning Structural Comparison of Protein Binding Sites

Simonovsky, M.; Meyers, J.

10.1101/600304 — bioinformatics — Posted on 2019-04-05

2549 ERASE: Extended Randomization for assessment of annotation enrichment in ASE datasets

D'Sa, K.; Reynolds, R. H.; Guelfi, S.; Zhang, D.; Ruiz, S. G.; Internatl Parkinson's Disease Genomics Consortium, ; System Genomics of Parkinson's Disease (SGPD), ; Hardy, J.; Gagliano Taliun, S. A.; Small, K. S.; Ryten, M.; Botia, J. A.

10.1101/600411 — bioinformatics — Posted on 2019-04-05

2550 ADSoluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer's disease progression

De, S.; Whiten, D. R.; Ruggeri, F. S.; Hughes, C.; Rodrigues, M.; Sideris, D. I.; Taylor, C. G.; Aprile, F. A.; Muyldermans, S.; Knowles, T. P. J.; Vendruscolo, M.; Bryant, C. E.; Blennow, K.; Skoog, I.; Kern, S.; Zetterberg, H.; Klenerman, D.

10.1101/600346 — neuroscience — Posted on 2019-04-05

2551 Measuring shared responses across subjects using intersubject correlation

Nastase, S. A.; Gazzola, V.; Hasson, U.; Keysers, C.

10.1101/600114 — neuroscience — Posted on 2019-04-05

2552 Loss of Ku’s DNA end binding activity affects telomere length via destabilizing telomere-bound Est1 rather than altering TLC1 homeostasis

Lemon, L. D.; Morris, D. K.; Bertuch, A. A.

10.1101/600197 — molecular biology — Posted on 2019-04-05

2553 A Modified Injector and Sample Acquisition Protocol Can Improve Data Quality and Reduce Inter-Instrument Variability of the Helios Mass Cytometer

Lee, B. H.; Kelly, G.; Bradford, S.; Davila, M.; Guo, X. V.; Amir, E.-a. D.; Thrash, E. M.; Solga, M.; Lannigan, J.; Sellers, B.; Candia, J.; Tsang, J.; Montgomery, R.; Tamaki, S.; Sigdel, T.; Sarwal, M.; Lanier, L.; Tian, Y.; Kim, C.; Hinz, D.; Peters, B.; Sette, A.; Rahman, A.

10.1101/600130 — immunology — Posted on 2019-04-05

2554 Canonical NOTCH signaling controls the early progenitor state and emergence of the medullary epithelial lineage in fetal thymus development.

Liu, D.; Kousa, A.; O'Neill, K.; Guillemot, F.; Popis, M.; Farley, A. M.; Tomlinson, S. R.; Ulyanchenko, S.; Seymour, P. A.; Serup, P.; Koch, U.; Radtke, F.; Blackburn, C. C.

10.1101/600833 — developmental biology — Posted on 2019-04-05

2555 Perturbation of the human gut microbiome by a non-antibiotic drug contributes to the resolution of autoimmune disease

Nayak, R. R.; Alexander, M.; Stapleton-Grey, K.; Ubeda, C.; Scher, J. U.; Turnbaugh, P. J.

10.1101/600155 — microbiology — Posted on 2019-04-05

2556 Retrieval of whole human genome clinical variant information through search motors

Yin, L.; di Iulio, J.; Lelong, S.; Wu, C.; Telenti, A.

10.1101/600098 — genomics — Posted on 2019-04-05

2557 The Draft Genome of Kochia scoparia and the Mechanism of Glyphosate Resistance via Transposon-Mediated EPSPS Tandem Gene Duplication

Patterson, E.; Saski, C. A.; Sloan, D. B.; Tranel, P.; Westra, P.; Gaines, T. A.

10.1101/600072 — genomics — Posted on 2019-04-05

2558 Kelch13 and MDR1 Polymorphisms, and Drug Effectiveness at Day 3 after Dihydroartemisinin-Piperaquine Treatment for Plasmodium falciparum Malaria on Bioko Island, Equatorial Guinea: 2014-2017

Zheng, Y. Z.; Chen, J. T.; Liang, X. Y.; Ehapo, C. S.; Eyi, U. M.; Huang, H. Y.; Chen, W. Z.; Lin, L. Y.; Xie, D. D.; Wang, Y. L.; Chen, G. W.; Liu, X. Z.; Zha, G. C.; Mo, H. T.; Chen, X. Y.; Li, J.; Jiang, T. T.; Lin, M.

10.1101/594366 — epidemiology — Posted on 2019-04-05

2559 Serostatus Testing & Dengue Vaccine Cost-Benefit Thresholds

Pearson, C. A.; Abbas, K.; Clifford, S.; Flasche, S.; Hladish, T. J.

10.1101/594556 — epidemiology — Posted on 2019-04-05

2560 Sagittal abdominal diameter and waist circumference are equally good as identifiers of cardiometabolic risk

Moller, G.; Ritz, C.; Kjoelbaek, L.; Vuholm, S.; Korndal, S. K. K.; Meinert Larsen, T. M.; Pedersen, O.; Saris, W.; Astrup, A.; Lauritzen, L.; Kristensen, M. B.; Vendelbo Lind, M.

10.1101/598078 — epidemiology — Posted on 2019-04-05

2561 Genetic contributions to health literacy

Fawns-Ritchie, C.; Davies, G.; Hagenaars, S. P.; Deary, I.

10.1101/595967 — epidemiology — Posted on 2019-04-05

2562 A three-years assessment of Ixodes ricinus-borne pathogens in a French peri-urban forest

Lejal, E.; Marsot, M.; Chalvet-Monfray, K.; Cosson, J.-F.; Moutailler, S.; Vayssier-Taussat, M.; Pollet, T.

10.1101/597013 — epidemiology — Posted on 2019-04-05

2563 Decoys and dilution: the impact of incompetent hosts on prevalence of Chagas disease

Zahid, M. H.; Kribs, C.

10.1101/597708 — epidemiology — Posted on 2019-04-05

2564 Diurnal profiles of physical activity and postures derived from wrist-worn accelerometry in UK adults

Perez-Pozuelo, I.; White, T.; Westgate, K.; Wijndaele, K.; Wareham, N.; Brage, S.

10.1101/600650 — epidemiology — Posted on 2019-04-05

2565 Emergence and molecular basis of azithromycin resistance in typhoidal Salmonella in Dhaka, Bangladesh

Hooda, Y.; Saha, S.; Sajib, M. S. I.; Rahman, H.; Luby, S. P.; Bondy-Denomy, J.; Santosham, M.; Andrews, J.; Saha, S.

10.1101/594531 — epidemiology — Posted on 2019-04-05

2566 Specific Disruption of Established P. aeruginosa Biofilms Using Polymer-Attacking Enzymes

Kovach, K.; Fleming, D.; Rumbaugh, K. P.; Gordon, V.

10.1101/598979 — microbiology — Posted on 2019-04-05

2567 Precocious Chondrocyte Differentiation Disrupts Skeletal Growth in Kabuki Syndrome Mice

Fahrner, J. A.; Lin, W.-Y.; Riddle, R. C.; Boukas, L.; DeLeon, V. B.; Chopra, S.; Lad, S. E.; Luperchio, T. R.; Hansen, K. D.; Bjornsson, H. T.

10.1101/599878 — genetics — Posted on 2019-04-05

2568 Second messengers and divergent HD-GYP enzymes regulate 3’,3’-cGAMP signaling

Wright, T. A.; Jiang, L.; Park, J. J.; Anderson, W. A.; Chen, G.; Hallberg, Z. F.; Nan, B.; Hammond, M. C.

10.1101/600031 — biochemistry — Posted on 2019-04-05

2569 The cerebellum is involved in processing of predictions and prediction errors in a fear conditioning paradigm

Ernst, T. M.; Brol, A. E.; Gratz, M.; Ritter, C.; Bingel, U.; Schlamann, M.; Maderwald, S.; Quick, H. H.; Merz, C. J.; Timmann, D.

10.1101/600494 — neuroscience — Posted on 2019-04-05

2570 Dysregulation of M segment gene expression contributes to influenza A virus host restriction

Calderon, B. M.; Danzy, S.; Delima, G. K.; Jacobs, N. T.; Ganti, K.; Hockman, M. R.; Conn, G. L.; Lowen, A. C.; Steel, J.

10.1101/599886 — microbiology — Posted on 2019-04-05

2571 Prediction of antiviral drugs against African Swine Fever Viruses based on protein-protein interaction analysis

zhu, z.; Fan, Y.; Cai, Z.; Zhang, Z.; Lu, C.; Zhang, G.; Jiang, T.; Peng, Y.

10.1101/599043 — bioinformatics — Posted on 2019-04-05

2572 Homeostasis in the Central Dogma of Molecular Biology

Perez-Ortin, J. E.; Chavez, S.; Tordera, V.

10.1101/599050 — molecular biology — Posted on 2019-04-05

2573 Streptococcus pneumoniae evades host cell phagocytosis and limits host mortality through its cell wall anchoring protein PfbA

Yamaguchi, M.; Hirose, Y.; Takemura, M.; Ono, M.; Sumitomo, T.; Nakata, M.; Terao, Y.; Kawabata, S.

10.1101/599001 — microbiology — Posted on 2019-04-05

2574 A decrease in transcription capacity limits growth rate upon translation inhibition

Zhang, Q.; Brambilla, E.; Li, R.; Shi, H.; Cosentino Lagomarsino, M.; Sclavi, B.

10.1101/599183 — microbiology — Posted on 2019-04-05

2575 Quantifying the mechanics of locomotion of the schistosome pathogen with respect to changes in its physical environment

Zhang, S.; Skinner, D.; Joshi, P.; Criado-Hidalgo, E.; Yeh, Y.-T.; Lasheras, J. C.; Caffrey, C. R.; del Alamo, J. C.

10.1101/599993 — biophysics — Posted on 2019-04-05

2576 Cox regression increases power to detect genotype-phenotype associations in genomic studies using the electronic health record

Hughey, J. J.; Rhoades, S. D.; Fu, D. Y.; Bastarache, L.; Denny, J. C.; Chen, Q.

10.1101/599910 — bioinformatics — Posted on 2019-04-05

2577 From isochorismate to salicylate: a new reaction mechanism for salicylic acid biosynthesis

Rekhter, D.; Ding, Y.; Luedke, D.; Feussner, K.; Wiermer, M.; Zhang, Y.; Feussner, I.

10.1101/600692 — plant biology — Posted on 2019-04-05

2578 Bet-hedging across generations can affect the evolution of variance-sensitive strategies within generations

Haaland, T. R.; Wright, J.; Ratikainen, I. I.

10.1101/600452 — evolutionary biology — Posted on 2019-04-05

2579 Using deep neural networks to detect complex spikes of cerebellar Purkinje Cells

Markanday, A.; Bellet, J.; Bellet, M. E.; Hafed, Z. M.; Thier, P.

10.1101/600536 — neuroscience — Posted on 2019-04-05

2580 Scopolamine and medial frontal stimulus-processing during interval timing

Zhang, Q.; Jung, D.; Larson, T.; Kim, Y.; Narayanan, N.

10.1101/598862 — neuroscience — Posted on 2019-04-05

2581 A simple and efficient CRISPR technique for protein tagging

Zeng, F.; Beck, V.; Schuierer, S.; Garnier, I.; Manneville, C.; Agarinis, C.; Morelli, L.; Quinn, L.; Knehr, J.; Roma, G.; Bassilana, F.; Nash, M. S.

10.1101/597971 — cell biology — Posted on 2019-04-05

2582 Prediction of the Effect of Naturally Occurring Missense Mutations on Cellular N-Acetyl-Glucosaminidase Enzymatic Activity

Ford, C. T.; Nodzak, C. M.; Uppal, A.; Shi, X.

10.1101/598870 — bioinformatics — Posted on 2019-04-05

2583 Elevated prevalence of azole resistant Aspergillus fumigatus in urban versus rural environments in the United Kingdom

Sewell, T. R.; Zhang, Y.; Brackin, A. P.; Shelton, J. M.; Rhodes, J.; Fisher, M. C.

10.1101/598961 — microbiology — Posted on 2019-04-05

2584 Tomato spotted wilt virus manipulates the reproduction of its insect vector, western flower thrips (Frankliniella occidentalis), to facilitate transmission

Wan, Y.; Hussain, S.; Xu, B.; Xie, W.; Wang, S.; Zhang, Y.; Zhou, X.; Wu, Q.

10.1101/598920 — ecology — Posted on 2019-04-05

2585 A generalization of partial least squares regression and correspondence analysis for categorical and mixed data: An application with the ADNI data

Beaton, D.; Alzheimer's Disease Neuroimaging Initiative, ; Saporta, G.; Abdi, H.

10.1101/598888 — bioinformatics — Posted on 2019-04-05

2586 Restoration of Susceptibility to Amikacin by 8-Hydroxyquinoline Analogs Complexed to Zinc

Magallon, J.; Chiem, K.; Tran, T.; Jimenez, V.; Ramirez, M. S.; Tolmasky, M.

10.1101/598912 — microbiology — Posted on 2019-04-05

2587 A comparative analysis of histone methyltransferases and demethylases in insect genome: A meta-analysis

Gulati, P.; Kohli, S.; Narang, A.; Brahmachari, V.

10.1101/598946 — genomics — Posted on 2019-04-05

2588 A divisive model of evidence accumulation explains uneven weighting of evidence over time

Keung, W.; Hagen, T. A.; Wilson, R. C.

10.1101/598789 — neuroscience — Posted on 2019-04-05

2589 Repeated phenotypic selection for cuticular blackness of armyworm larvae decreased stress resistance

Hayakawa, Y.; Matsumura, T.; Taya, H.; Matsumoto, H.

10.1101/598102 — physiology — Posted on 2019-04-05

2590 The speciation and hybridization history of the genus Salmonella

Criscuolo, A.; Issenhuth-Jeanjean, S.; Didelot, X.; Thorell, K.; Hale, J.; Parkhill, J.; Thomson, N.; Weill, F.-X.; Falush, D.; Brisse, S.

10.1101/598235 — microbiology — Posted on 2019-04-05

2591 A modeling algorithm for exploring the architecture and construction of bird nests

Jessel, H. R.; Aharoni, L.; Efroni, S.; Bachelet, I.

10.1101/600718 — biophysics — Posted on 2019-04-05

2592 Identification of novel genes involved in phosphate accumulation in Lotus japonicus through Genome Wide Association mapping of root system architecture and anion content

Giovannetti, M.; Goeschl, C.; Andersen, S. U.; Kopriva, S.; Busch, W.

10.1101/600726 — plant biology — Posted on 2019-04-05

2593 Inferring the function performed by a recurrent neural network

Chalk, M.; Tkacik, G.; Marre, O.

10.1101/598086 — neuroscience — Posted on 2019-04-05

2594 Budgerigars adopt robust, but idiosyncratic flight paths

Karmaker, D.; Schiffner, I.; Srinivasan, M.

10.1101/598680 — neuroscience — Posted on 2019-04-05

2595 Dendritic spines on GABAergic neurons respond to cholinergic signaling in the Caenorhabditis elegans motor circuit.

Cuentas-Condori, A. A.; Mulcahy, B.; He, S.; Palumbos, S.; Zhen, M.; Miller, D. M.

10.1101/598714 — neuroscience — Posted on 2019-04-05

2596 Resolution of the proteome, transcript and ionome dynamics upon Zn re-supply in Zn-deficient Arabidopsis

Arsova, B.; Amini, S.; Scheepers, M.; Baiwir, D.; Mazzucchelli, G.; Carnol, M.; Bosman, B.; Motte, P.; de Pauw, E.; Watt, M.; Hanikenne, M.

10.1101/600569 — plant biology — Posted on 2019-04-05

2597 iRhom2 serves as a facilitator in obesity by enhancing adipose inflammation and insulin resistance

Xu, M.; Ge, C.; Qin, Y.; Lou, D.; Li, Q.; Feng, J.; Wu, Y.; Hu, L.; Huang, P.; Tan, J.

10.1101/600460 — pathology — Posted on 2019-04-05

2598 Resting Eyes Closed Beta-Phase High Gamma-Amplitude Coupling Deficits in Children with Attention Deficit Hyperactivity Disorder

Ibanez-Soria, D.; Kroupi, E.; Rojas, A.; Castellano, M.; Picardo, J.; Garcia Banda, G.; Servera, M.; Ruffini, G.; Soria-Frisch, A.

10.1101/598003 — neuroscience — Posted on 2019-04-05

2599 Coupling multiplex pre-amplification and droplet digital PCR for longitudinal monitoring of ESR1 and PIK3CA mutations from plasma cell-free DNA

Yao, H.; Wu, G.; Das, S.; MacKenzie, C.; Gao, H.; Rimkunas, V.; Zhang, Z.; Ferro, S.; Roden, A.; Korpal, M.; Schindler, J.; Smith, P.; Yu, L.; Zhu, P.; Kumar, P.

10.1101/598847 — genetics — Posted on 2019-04-05

2600 Misfolded Amyloid β-42 induced impairment of the endo-lysosomal pathway revealed by real-time optical monitoring

Marshall, K.; Vadukul, D.; Staras, K.; Serpell, L.

10.1101/598540 — neuroscience — Posted on 2019-04-05

2601 Complementing 16S rRNA gene amplicon sequencing with estimates of total bacterial load to infer absolute species concentrations in the vaginal microbiome

Tettamanti Boshier, F.; Srinivasan, S.; Lopez, A.; Hoffman, N. G.; Proll, S.; Fredricks, D. N.; Schiffer, J. T.

10.1101/598771 — microbiology — Posted on 2019-04-05

2602 Pseudogenization, genome streamlining and specific gene repertoire landmark the genomes of Carnobacterium maltaromaticum isolated from diseased sharks

Martinez Steele, L.; Lowe, C.; Okihiro, M.; Dillon, J.; Berlemont, R.

10.1101/600684 — genomics — Posted on 2019-04-05

2603 Raptor genomes reveal evolutionary signatures of predatory and nocturnal lifestyles

Cho, Y. S.; Jun, J.; Kim, J. A.; Kim, H.-M.; Chung, O.; Kang, S.-G.; Park, J.-Y.; Kim, H.-J.; Kim, S.; Kim, H.-J.; Jang, J.-h.; Na, K.-J.; Kim, J.; Park, S. G.; Lee, H.-Y.; Manica, A.; Mindell, D. P.; Puchs, J.; Edwards, J. S.; Weber, J. A.; Witt, C. C.; Yeo, J.-H.; Kim, S.; Bhak, J.

10.1101/598821 — genomics — Posted on 2019-04-05

2604 Long-term intrahost evolution of methicillin-resistant Staphylococcus aureus among cystic fibrosis patients with respiratory carriage

Azarian, T.; Ridgway, J. P.; Yin, Z.; David, M.

10.1101/599431 — evolutionary biology — Posted on 2019-04-05

2605 Extensive ribosome and RF2 rearrangements during translation termination

Svidritskiy, E.; Demo, G.; Loveland, A. B.; Xu, C.; Korostelev, A. A.

10.1101/600445 — cell biology — Posted on 2019-04-05

2606 Non-Linear Realignment Improves Hippocampus Subfield Segmentation

Shaw, T. B.; Bollmann, S.; Atcheson, N. T.; Guo, C.; Fripp, J.; Salvado, O.; Barth, M.

10.1101/597856 — neuroscience — Posted on 2019-04-05

2607 Membrane Protrusion Formation Mediated by Rho/ROCK Signalling and Modulation of Chloride Flux

Hori, A.; NIshide, K.; Yasukuni, Y.; Haga, K.; Kakuta, W.; Ishikawa, Y.; Hayes, M.; Ohnuma, S.-i.; Kiyonari, H.; Kimura, K.; Kondo, T.; Sasai, N.

10.1101/600379 — cell biology — Posted on 2019-04-05

2608 Modulation of adult-born neuron excitability by coupling to GABAergic networks

Yang, S.-m.; Groisman, A.; Schinder, A.

10.1101/598615 — neuroscience — Posted on 2019-04-05

2609 Polygenic architecture of human neuroanatomical diversity

Biton, A.; Traut, N.; Poline, J.-B.; Aribisala, B. S.; Bastin, M. E.; Bülow, R.; Cox, S. R.; Deary, I. J.; Grabe, H. J.; Hagenaars, S.; Hashimoto, R.; Munoz Maniega, S.; Nauck, M.; Royle, N. A.; Teumer, A.; Valdes Hernandez, M.; Völker, U.; Wardlaw, J. M.; Wittfeld, K.; Alzheimer's Disease Neuroimaging Initiative, ; Bourgeron, T.; Toro, R.

10.1101/592337 — neuroscience — Posted on 2019-04-05

2610 Joint RElaxation-Diffusion Imaging Moments (REDIM) to probe neurite microstructure

Ning, L.; Gagoski, B.; Szczepankiewicz, F.; Westin, C.-F.; Rathi, Y.

10.1101/598375 — neuroscience — Posted on 2019-04-05

2611 Phase dependence of response curves to stimulation and their relationship: from a Wilson-Cowan model to essential tremor patient data

Duchet, B.; Weerasinghe, G.; Cagnan, H.; Brown, P.; Bick, C.; Bogacz, R.

10.1101/535880 — neuroscience — Posted on 2019-04-05

2612 On the prediction of protein abundance from RNA

Magnusson, R.; Rundquist, O.; Kim, M. J.; Hellberg, S.; Na, C. H.; Benson, M.; Gomez-Cabrero, D.; Kockum, I. S.; Tegner, J.; Piehl, F.; Jagodic, M.; Mellergard, J.; Altafini, C.; Ernerudh, J.; Jenmalm, M. C.; Nestor, C. E.; Kim, M.-S.; Gustafsson, M.

10.1101/599373 — bioinformatics — Posted on 2019-04-05

2613 Altered dynamics may drift pathological fibrillization in membraneless organelles

Tuu-Szabo, B.; HOFFKA, G.; DURO, N.; KOCZY, L.; Fuxreiter, M.

10.1101/598185 — bioinformatics — Posted on 2019-04-05

2614 Auditory and semantic cues facilitate decoding of visual object category in MEG

Brandman, T.; Avancini, C.; Leticevscaia, O.; Peelen, M. V.

10.1101/598516 — neuroscience — Posted on 2019-04-05

2615 Behavioural and neural interactions between objective and subjective performance in a Matching Pennies game

Dyson, B.; Musgrave, C.; Rowe, C.; Sandhur, R.

10.1101/598466 — neuroscience — Posted on 2019-04-05

2616 Initial neural representation of individual rules after first-time instruction

Ruge, H.; Schaefer, T. A. J.; Zwosta, K.; Mohr, H.; Wolfensteller, U.

10.1101/598276 — neuroscience — Posted on 2019-04-05

2617 A simplified transposon mutagenesis method to perform phenotypic forward genetic screens in cultured cells

Feddersen, C. R.; Wadsworth, L. S.; Zhu, E. Y.; Vaughn, H. R.; Voigt, A. P.; Riordan, J. D.; Dupuy, A. J.

10.1101/598474 — genomics — Posted on 2019-04-05

2618 Ultra-local adaptation due to genetic accommodation

Sun, S.-J.; Catherall, A.; Pascoal, S.; Jarrett, B.; Miller, S.; Sheehan, M.; Kilner, R.

10.1101/598292 — evolutionary biology — Posted on 2019-04-05

2619 Supra-molecular organization of the pyoverdine bio-synthetic pathway in Pseudomonas aeruginosa.

Gasser, V.; Malrieu, M.; Forster, A.; Mely, Y.; Schalk, I. J.; Godet, J.

10.1101/438713 — biophysics — Posted on 2019-04-05

2620 Ensemble modeling of auditory streaming reveals potential sources of bistability across the perceptual hierarchy

Little, D. F.; Snyder, J. S.; Elhilali, M. F.

10.1101/598631 — animal behavior and cognition — Posted on 2019-04-05

2621 Induction of the nicotinamide riboside kinase NAD+ salvage pathway in skeletal muscle of H6PDH KO mice

Doig, C. L.; Zielinska, A. E.; Oakey, L. A.; Fletcher, R. S.; El Hassan, Y. S.; Garten, A.; Cartwright, D.; Heising, S.; Alsheri, A.; Watson, D. G.; Adamski, J.; Tennant, D. A.; Lavery, G. G.

10.1101/567297 — physiology — Posted on 2019-04-05

2622 APOL1-G0 protects podocytes in a mouse model of HIV-associated nephropathy

Bruggeman, L. A.; Wu, Z.; Luo, L.; Madhavan, S.; Drawz, P. E.; Thomas, D. B.; Barisoni, L.; O'Toole, J. F.; Sedor, J. R.

10.1101/598557 — pathology — Posted on 2019-04-05

2623 Pathological and non-pathological aging, SAMP8 and SAMR1. What do hippocampal neuronal populations tell us?

Lagartos Donate, M. j.; Gonzalez-Fuentes, J.; Marcos-Rabal, P.; Insausti, R.; Arroyo-Jimenez, M. d. M.

10.1101/598599 — neuroscience — Posted on 2019-04-05

2624 Mid-lateral Cerebellar Purkinje Cells Provide a Cognitive Error Signal When Monkeys Learn a New Visuomotor Association

Sendhilnathan, N.; Ipata, A. E.; Goldberg, M. E.

10.1101/600221 — neuroscience — Posted on 2019-04-05

2625 Decoding neuronal diversity by single-cell Convert-seq

Luginbuhl, J.; Kouno, T.; Nakano, R.; Chater, T. E.; Sivaraman, D. M.; Kishima, M.; Roudnicky, F.; Carninci, P.; Plessy, C.; Shin, J. W.

10.1101/600239 — neuroscience — Posted on 2019-04-05

2626 The effect of acute stress on the balance between goal-directed and habit networks in obsessive-compulsive disorder.

van der Straten, A.; van Leeuwen, W.; Denys, D.; van Marle, H.; van Wingen, G.

10.1101/598268 — neuroscience — Posted on 2019-04-05

2627 Vegetative Cell and Spore Proteomes of Peptoclostridium difficile show finite differences and reveal potential biomarkers.

Abhyankar, W.; Zheng, L.; Brul, S.; de Koster, C. G.; de Koning, L. J.

10.1101/598045 — microbiology — Posted on 2019-04-05

2628 Genetic Associations with Mathematics Tracking and Persistence in Secondary School

Harden, K. P.; Domingue, B. W.; Belsky, D. W.; Boardman, J.; Crosnoe, R.; Malanchini, M.; Nivard, M. G.; Tucker-Drob, E. M.; Harris, K. M.

10.1101/598532 — genetics — Posted on 2019-04-05

2629 PIRATE: A fast and scalable pangenomics toolbox for clustering diverged orthologues in bacteria

Bayliss, S. C.; Thorpe, H. A.; Coyle, N. M.; Sheppard, S. K.; Feil, E. J.

10.1101/598391 — bioinformatics — Posted on 2019-04-05

2630 To enrich or not to enrich: Enhancing (glyco)peptide ionization using the CaptiveSpray nanoBooster ™

Alagesan, K.; Kolarich, D.

10.1101/597922 — biochemistry — Posted on 2019-04-05

2631 Resting Eyes Closed Beta-Phase High Gamma-Amplitude Coupling Deficits in Children with Attention Deficit Hyperactivity Disorder

Ibanez Soria, D.; Kroupi, E.; Rojas, A.; Castellano, M.; Picardo, J.; Garcia Banda, G.; Servera, M.; Ruffini, G.; Soria Frisch, A.

10.1101/598003 — neuroscience — Posted on 2019-04-05

2632 Cognitive Improvements after Intermittent Deep Brain Stimulation of the Nucleus Basalis of Meynert in a Transgenic Rat Model for Alzheimer’s disease; a Preliminary Approach

Koulousakis, P.; van den Hove, D.; Visser-Vandewalle, V.; Sesia, T.

10.1101/600296 — neuroscience — Posted on 2019-04-05

2633 Pangenome analysis reveals genetic isolation in Campylobacter hyointestinalis subspecies adapted to different mammalian hosts

Costa, D.; Levesque, S.; Kumar, N.; Fresia, P.; Ferres, I.; Lawley, T. D.; Iraola, G.

10.1101/600403 — genomics — Posted on 2019-04-05

2634 Transcriptome profile of Carrizo citrange roots in response to Phytophthora parasitica infection

Naveed, Z. A.; Huguet-Tapia, J. C.; Ali, G. S.

10.1101/598250 — genomics — Posted on 2019-04-05

2635 Field assessment of precocious maturation in salmon parr using ultrasound imaging

Nevoux, M.; Marchand, F.; Destouches, J.-P.; Forget, G.; Huteau, D.; Tremblay, J.

10.1101/425561 — ecology — Posted on 2019-04-05

2636 Transmission of West Nile virus and other temperate mosquito-borne viruses occurs at lower environmental temperatures than tropical diseases

Shocket, M. S.; Verwillow, A. B.; Numazu, M. G.; Slamani, H.; Cohen, J. M.; El Moustaid, F.; Rohr, J. R.; Johnson, L. R.; Mordecai, E. A.

10.1101/597898 — ecology — Posted on 2019-04-05

2637 Electric-induced reversal of morphogenesis in Hydra regeneration

Braun, E.; Ori, H.

10.1101/600395 — biophysics — Posted on 2019-04-05

2638 Serum proteomic approach for differentiation of frail and non-frail elderly

Dey, S.; Agnihotri, V.; Gupta, A.; Pradhan, R.; Venugopalan, G. V.; Bajpai, S.; Dey, A. B.

10.1101/600262 — biophysics — Posted on 2019-04-05

2639 EMT-induced cell mechanical changes enhance mitotic rounding strength

Hosseini, K.; Taubenberger, A.; Werner, C.; Fischer-Friedrich, E.

10.1101/598052 — biophysics — Posted on 2019-04-05

2640 The ELIXIR Core Data Resources: fundamental infrastructure for the life sciences

10.1101/598318 — bioinformatics — Posted on 2019-04-05

2641 Identification of viruses with the potential to infect human

Zhang, Z.; Cai, Z.; Tan, Z.; Lu, C.; Jiang, T.; Zhang, G.; Peng, Y.

10.1101/597963 — bioinformatics — Posted on 2019-04-05

2642 SUPPRESSOR OF MAX2 1-LIKE 5 promotes secondary phloem formation during radial stem growth

Wallner, E.-S.; Jouannet, V.; Greb, T.

10.1101/600312 — plant biology — Posted on 2019-04-05

2643 Leptin deficient rats develop nonalcoholic steatohepatitis with unique disease progression

Lu, P.; Yang, G.; He, W.; Wu, W.; Qi, L.; Shen, S.; Rao, J.; Fan, G.; Xue, Z.; Zhang, P.; Jiang, C.; Zhu, X.

10.1101/594978 — pathology — Posted on 2019-04-05

2644 Quality control of large genome datasets using genome fingerprints

Robinson, M.; Glusman, G.

10.1101/600254 — genomics — Posted on 2019-04-05

2645 COUSIN (COdon Usage Similarity INdex): a normalized index of Codon Usage Preferences.

Bourret, J.; Alizon, S.; Bravo, I. G.

10.1101/600361 — bioinformatics — Posted on 2019-04-05

2646 StanDep: capturing transcriptomic variability improves context-specific metabolic models

Joshi, C. J.; Schinn, S.-M.; Richelle, A.; Shamie, I.; O'Rourke, E. J.; Lewis, N.

10.1101/594861 — systems biology — Posted on 2019-04-05

2647 Modeling Bottom-Up and Top-Down Attention with a Neurodynamic Model of V1

Berga, D.; Otazu, X.

10.1101/590174 — neuroscience — Posted on 2019-04-05

2648 Comparison of prokaryotic communities between the fields showing different disinfestation effects by anaerobic soil disinfestation

Lee, C. G.; Iida, T.; Matusda, E.; Yoshida, K.; Kawabe, M.; Maeda, M.; Watanabe, H.; Muramoto, Y.; Otani, Y.; Nakaho, K.; Ohkuma, M.

10.1101/596825 — microbiology — Posted on 2019-04-05

2649 An evaluation of pool-sequencing transcriptome-based exon capture for population genomics of non-model species

Deleury, E.; Guillemaud, T.; Blin, A.; Lombaert, E.

10.1101/583534 — genomics — Posted on 2019-04-05

2650 Linking Allele-Specific Expression And Natural Selection In Wild Populations

Laso-Jadart, R.; Sugier, K.; Petit, E.; Labadie, K.; Peterlongo, P.; Ambroise, C.; Wincker, P.; Jamet, J.-L.; Madoui, M.-A.

10.1101/599076 — genomics — Posted on 2019-04-05

2651 Surveying insect flower visitors to crops in New Zealand and Australia

Howlett, B. G.; Evans, L. J.; Kendall, L. K.; Rader, R.; McBrydie, H. M.; Read, S. F. J.; Cutting, B. T.; Robson, A.; Pattemore, D. E.; Willcox, B. K.

10.1101/373126 — ecology — Posted on 2019-04-05

2652 Neutrality in the Metaorganism

Sieber, M.; Pita, L.; Weiland-Bräuer, N.; Dirksen, P.; Wang, J.; Mortzfeld, B.; Franzenburg, S.; Schmitz, R. A.; Baines, J. F.; Fraune, S.; Hentschel, U.; Schulenburg, H.; Bosch, T. C. G.; Traulsen, A.

10.1101/367243 — ecology — Posted on 2019-04-05

2653 Pan-Cancer Exploration of mRNA Mediated Dysregulated Pathways in the Cancer Genomics Cloud

Linan, M.; Wang, J.; Dinu, V.

10.1101/599225 — bioinformatics — Posted on 2019-04-05

2654 Immortalization of different breast epithelial cell types results in distinct mitochondrial mutagenesis

Kwon, S.; Kim, S. S.; Nebeck, H. E.; Ahn, E. H.

10.1101/592832 — genomics — Posted on 2019-04-05

2655 Computational analysis of molecular networks using spectral graph theory, complexity measures and information theory

Huang, C.-H.; Tsai, J. J. P.; Kurubanjerdjit, N.; Ng, K.-L.

10.1101/536318 — systems biology — Posted on 2019-04-05

2656 Δ9-tetrahydrocannabinol Attenuates Oxycodone Self-Administration Under Extended Access Conditions

Nguyen, J. D.; Grant, Y.; Creehan, K. M.; Hwang, C. S.; Vandewater, S.; Janda, K. D.; Cole, M.; Taffe, M. A.

10.1101/239038 — neuroscience — Posted on 2019-04-05

2657 Infection of Plasmodiophora brassicae changes the fungal endophyte community of tumourous stem mustard roots as revealed by high-throughput sequencing and culture-dependent methods

Tian, X.; Wang, D.; Mao, Z.; Pan, L.; Liao, J.; Cai, Z.

10.1101/590018 — microbiology — Posted on 2019-04-05

2658 Negative T cell selection on non-random peptides promotes robust self-nonself discrimination

Wortel, I. M. N.; Kesmir, C.; De Boer, R. J.; Mandl, J. N.; Textor, J.

10.1101/403428 — immunology — Posted on 2019-04-05

2659 Multivariate methods for testing hypotheses of temporal community dynamics

Buckley, H. L.; Day, N. J.; Case, B. S.; Lear, G.; Ellison, A. M.

10.1101/362822 — ecology — Posted on 2019-04-05

2660 The effect of spatial variation for predicting aphid outbreaks

Damgaard, C.; Bruus, M.; Axelsen, J. A.

10.1101/367953 — ecology — Posted on 2019-04-05

2661 EECoG-Comp: An Open Source Platform for Concurrent EEG/ECoG Comparisons: applications to connectivity studies

Wang, Q.; Valdes-Hernandez, P. A.; Paz-Linares, D.; Bosch-Bayard, J.; Oosugi, N.; Komatsu, M.; Fujii, N.; Valdes-Sosa, P. A.

10.1101/350199 — bioinformatics — Posted on 2019-04-05

2662 Developmental and cell-specific expression of Cacna1d splice variants

LaCarubba, B.; Bunda, A.; Savage, K.; Sargent, H.; Akiki, M.; Foxall, T.; Andrade, A.

10.1101/598722 — neuroscience — Posted on 2019-04-04

2663 Geosmin attracts Aedes aegypti mosquitoes to oviposition sites

Melo, N.; Wolff, G. H.; Luis Costa-da-Silva, A.; Arribas, R.; Fernandez Triana, M.; Gugger, M.; Riffell, J. A.; DeGennaro, M.; Stensmyr, M. C.

10.1101/598698 — neuroscience — Posted on 2019-04-04

2664 Neuronal circuitry for stimulus selection in the visual system

Fernandes, A. M.; Larsch, J.; Donovan, J. C.; Helmbrecht, T. O.; Mearns, D.; Kölsch, Y.; Dal Maschio, M.; Baier, H.

10.1101/598383 — neuroscience — Posted on 2019-04-04

2665 Increased expression of schizophrenia-associated gene C4 leads to hypoconnectivity of prefrontal cortex and reduced social interaction

Comer, A. L.; Jinadasa, T.; Kretsge, L. N.; Nguyen, T. P. H.; Lee, J.; Newmark, E. R.; Hausmann, F. S.; Rosenthal, S.; Liu Kot, K.; Yen, W. W.; Cruz-Martin, A.

10.1101/598342 — neuroscience — Posted on 2019-04-04

2666 Trans-synaptic Fish-lips Signaling Prevents Misconnections between Non-synaptic Partner Olfactory Neurons

Xie, Q.; Wu, B.; Li, J.; Li, H.; Luginbuhl, D.; Xu, C.; Wang, X.; Luo, L.

10.1101/600064 — neuroscience — Posted on 2019-04-04

2667 Gallery Game: Smartphone-based Assessment of Long-Term Memory in Adults at Risk of Alzheimer’s Disease

Lancaster, C.; Koychev, I.; Blane, J.; Chinner, A.; Chatham, C.; Taylor, K.; Hinds, C.

10.1101/599175 — neuroscience — Posted on 2019-04-04

2668 Malaria vaccine candidates displayed on novel virus-like particles are immunogenic and induce transmission-blocking activity

Chan, J.-A.; Wetzel, D.; Reiling, L.; Miura, K.; Drew, D. R.; Gilson, P. R.; Anderson, D. A.; Richards, J. S.; Long, C. A.; Suckow, M.; Jenzelewski, V.; Tsuboi, T.; Boyle, M. J.; Piontek, M.; Beeson, J. G.

10.1101/597831 — immunology — Posted on 2019-04-04

2669 Within-finger maps of tactile and nociceptive input in the human parietal cortex

Mancini, F.; Sereno, M. I.; Lee, M.-H.; Iannetti, G. D.; Tracey, I.

10.1101/599167 — neuroscience — Posted on 2019-04-04

2670 NgAgo-enhanced homologous recombination in E. coli is mediated by DNA endonuclease activity

Lee, K. Z.; Mechikoff, M. A.; Kikla, A.; Liu, A.; Pandolfi, P.; Gimble, F. S.; Solomon, K.

10.1101/597237 — molecular biology — Posted on 2019-04-04

2671 Comparison of prokaryotic communities between the fields showing different disinfestation effects by anaerobic soil disinfestation

Lee, C. G.; Iida, T.; Matusda, E.; Yoshida, K.; Kawabe, M.; Maeda, M.; Watanabe, H.; Muramoto, Y.; Otani, Y.; Nakaho, K.; Ohkuma, M.

10.1101/596825 — microbiology — Posted on 2019-04-04

2672 Early Detection of Ovarian Cancer Using Cells Sourced from a Local Microenvironment

Galey, M. M.; Young, A. N.; Petukhova, V. Z.; Wang, M.; Wang, J.; Burdette, J. E.; Sanchez, L. M.

10.1101/597740 — cancer biology — Posted on 2019-04-04

2673 Sequence Analysis and Homology Modelling of SmHQT Protein, a Key Player in Chlorogenic Acid Pathway of Eggplant

Kaushik, P.; Saini, D. K.

10.1101/599282 — bioinformatics — Posted on 2019-04-04

2674 Concordance of Race Documented in Electronic Health Records and Genetic Ancestry

Walunas, T. L.; Pacheco, J. A.; Jackson, K. L.; Roberts, A.; Armstrong, L. L.; Behrens, J.; Hayes, M. G.; Kho, A. N.

10.1101/598706 — bioinformatics — Posted on 2019-04-04

2675 \"Stretch-Growth\" of Motor Axons in Custom Mechanobioreactors to Generate Long-Projecting Axonal and Axonal-Myocyte Constructs

Katiyar, K.; Struzyna, L.; Das, S.; Cullen, D. K.

10.1101/598755 — bioengineering — Posted on 2019-04-04

2676 Basal ganglia contributions during the learning of a visuomotor rotation: effect of dopamine, deep brain stimulation and reinforcement

Singh, P.; Lenka, A.; Stezin, A.; Jhunjhunwala, K.; Pal, P. K.; Ghosal, A.; Murthy, A.

10.1101/599308 — neuroscience — Posted on 2019-04-04

2677 Different Whole-Brain Functional Connectivity Correlates of Reactive-Proactive Aggression and Callous-Unemotional Traits in Disruptive Children and Adolescents

Werhahn, J. E.; Mohl, S.; Willinger, D.; Smigielski, L.; Roth, A.; Naaijen, J.; Mulder, L. M.; Glennon, J. C.; Hoekstra, P. J.; Dietrich, A.; Kleine Deters, R.; Aggensteiner, P. M.; Holze, N. E.; Baumeister, S.; Banaschewski, T.; Saam, M. C.; Schulze, U. M. E.; Lythgoe, D. J.; Sethi, A.; Craig, M.; Mastroianni, M.; Sagar-Ouriaghli, I.; Santosh, P. J.; Rosa, M.; Bargallo, N.; Castro-Fornieles, J.; Arango, C.; Penzol, M.; Zwiers, M. P.; Franke, B.; Buitelaar, J. K.; Walitza, S.; Brandeis, D.

10.1101/599548 — neuroscience — Posted on 2019-04-04

2678 New β-Lactamase Inhibitors Nacubactam and Zidebactam Improve the In Vitro Activity of β-Lactam Antibiotics Against Mycobacterium abscessus Complex Clinical Isolates

Kaushik, A.; Ammerman, N.; Parrish, N. M.; Nuermberger, E.

10.1101/597765 — microbiology — Posted on 2019-04-04

2679 Mitochondrial dysfunction and autophagy responses to skeletal muscle stress

Nichenko, A. S.; Southern, W. M.; Qualls, A. E.; Flemington, A. B.; Mercer, G. H.; Yin, A.; Yin, H.; Call, J. A.

10.1101/597476 — physiology — Posted on 2019-04-04

2680 Clinical long-read sequencing of the human mitochondrial genome for mitochondrial disease diagnostics

Wood, E.; Parker, M. D.; Dunning, M. J.; Hesketh, S.; Wang, D.; Pink, R.; Fratter, C.

10.1101/597187 — genomics — Posted on 2019-04-04

2681 Spatial density estimates of Eurasian lynx (Lynx lynx) in the French Jura and Vosges Mountains

Gimenez, O.; Gatti, S.; Duchamp, C.; Germain, E.; Laurent, A.; Zimmermann, F.; Marboutin, E.

10.1101/600015 — ecology — Posted on 2019-04-04

2682 Elevated LRRK2 and α-synuclein levels in CSF of infectious meningitis patients

Herbst, S.; Marais, S.; Gutierrez, M. G.; Waddell, S. J.; Wilkinson, R. J.; Lai, R. P.

10.1101/599381 — immunology — Posted on 2019-04-04

2683 Insights from Fisher’s geometric model on the likelihood of speciation under different histories of environmental change

Yamaguchi, R.; Otto, S. P.

10.1101/596866 — evolutionary biology — Posted on 2019-04-04

2684 A parallel cell-cycle entry pathway with inverted G1 signaling and alternate point of no return

Liu, C.; Konagaya, Y.; Chung, M.; Daigh, L.; Fan, Y.; Yang, H. W.; Terai, K.; Matsuda, M.; Meyer, T.

10.1101/600007 — cell biology — Posted on 2019-04-04

2685 Transcriptomic responses to warming and cooling of an Arctic tundra soil microbiome

Schostag, M. D.; Anwar, M. Z.; Jacobsen, C. S.; Larose, C.; Vogel, T. M.; Maccario, L.; Jacquiod, S.; Faucherre, S.; Prieme, A.

10.1101/599233 — microbiology — Posted on 2019-04-04

2686 Genomic Prediction of Depression Risk and Resilience Under Stress

Fang, Y.; Scott, L.; Song, P.; Burmeister, M.; Sen, S.

10.1101/599456 — genomics — Posted on 2019-04-04

2687 Ancestry-specific polygenic scores and SNP heritability of 25(OH)D in African- and European-ancestry populations

Hatchell, K. E.; Lu, Q.; Hebbring, S. J.; Michos, E. D.; Wood, A. C.; Engelman, C. D.

10.1101/596619 — genetics — Posted on 2019-04-04

2688 A meiosis-specific AAA+ assembly reveals repurposing of ORC during budding yeast gametogenesis

Villar-Fernandez, M. A.; Silva, R.; Pan, D.; Weir, E.; Sarembe, A.; Raina, V. B.; Weir, J. R.; Vader, G.

10.1101/598128 — biochemistry — Posted on 2019-04-04

2689 Optimal decoding of NFkB signaling dynamic

Maity, A.; Wollman, R.

10.1101/595272 — systems biology — Posted on 2019-04-04

2690 Anticipatory distractor suppression elicited by statistical regularities in visual search

Wang, B.; van Driel, J.; Ort, E.; Theeuwes, J.

10.1101/599134 — neuroscience — Posted on 2019-04-04

2691 A sparse EEG-informed fMRI model for hybrid EEG-fMRI neurofeedback prediction

Cury, C.; Maurel, P.; Gribonval, R.; Barillot, C.

10.1101/599589 — neuroscience — Posted on 2019-04-04

2692 A passive, camera-based head-tracking system for real-time, 3D estimate of head position and orientation in rodents

Vanzella, W.; Grion, N.; Bertolini, D.; Perissinotto, A.; Zoccolan, D.

10.1101/599365 — neuroscience — Posted on 2019-04-04

2693 Dementia risk genes engage gene networks poised to tune the immune response towards chronic inflammatory states

Rexach, J. E.; Swarup, V.; Chang, T. S.; Geschwind, D. H.

10.1101/597542 — neuroscience — Posted on 2019-04-04

2694 Peptidylarginine Deiminase inhibition abolishesthe production of large extracellular vesicles fromGiardia intestinalis, affecting host-pathogeninteractions by hindering adhesion to host cells.

Gavinho, B.; Rossi, I.; Evans-osses, I.; Lange, S.; Ramirez, M. I.

10.1101/586438 — microbiology — Posted on 2019-04-04

2695 Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci

Gutierrez-Arcelus, M.; Baglaenko, Y.; Arora, J.; Hannes, S.; Luo, Y.; Amariuta, T.; Teslovich, N.; Rao, D. A.; Ermann, J.; Jonsson, A. H.; Navarrete, C.; Gregersen, P. K.; Esko, T.; Brenner, M. M.; Raychaudhuri, S.

10.1101/599449 — genomics — Posted on 2019-04-04

2696 Validation of new tools to identify expanded repeats: an intronic pentamer expansion in RFC1 causes CANVAS

10.1101/597781 — genetics — Posted on 2019-04-04

2697 Long-term intrahost evolution of methicillin-resistant Staphylococcus aureus among cystic fibrosis patients with respiratory carriage

Azarian, T.; Ridgway, J. P.; Yin, Z.; David, M.

10.1101/599431 — evolutionary biology — Posted on 2019-04-04

2698 Computing wide range of protein/peptide features from their sequence and structure

Pande, A.; Patiyal, S.; Lathwal, A.; Arora, C.; Kaur, D.; Dhall, A.; Mishra, G.; Kaur, H.; Sharma, N.; Jain, S.; Usmani, S. S.; Agrawal, P.; Kumar, R.; Kumar, V.; Raghava, G. P. S.

10.1101/599126 — bioinformatics — Posted on 2019-04-04

2699 The HAC1 Histone Acetyltransferase Promotes Leaf Senescence via Regulation of ERF022

Hinckley, W. E.; Keymanesh, K.; Cordova, J. A.; Brusslan, J. A.

10.1101/599902 — plant biology — Posted on 2019-04-04

2700 Muscle oxygenation maintained during repeated sprints despite inspiratory muscle loading

Rodriguez, R. F.; Townsend, N. E.; Aughey, R. J.; Billaut, F.

10.1101/599936 — physiology — Posted on 2019-04-04

2701 Symptom Severity in Youths with Attention Deficit Hyperactivity Disorder Associated with Normalizing Effects of Treatment on fMRI Response during a Stop Signal Task

Hegarty, C. E.; Gupta, M. W.; Miller, E.; Terashima, K.; Loo, S.; McCracken, J.; McGough, J.; Bilder, R. M.; Poldrack, R. A.; Galvan, A.; Bookheimer, S.

10.1101/599803 — neuroscience — Posted on 2019-04-04

2702 Lamina-specific neuronal properties promote robust, stable signal propagation in feedforward networks

Han, D.; De Schutter, E.; Hong, S.

10.1101/596676 — neuroscience — Posted on 2019-04-04

2703 NRF2 drug repurposing using a question-answer artificial intelligence system

Mickael, M. E. K.; Pajares, M.; Enache, I.; Manda, G.; Cuadrado, A.

10.1101/594622 — neuroscience — Posted on 2019-04-04

2704 Diminution of feeding response in Helicoverpa armigera by inhibition or silencing of sugar gustatory receptor

Agnihotri, A. R.; Zunjarrao, S. S.; Nagare, M. R.; Joshi, R. S.

10.1101/599324 — molecular biology — Posted on 2019-04-04

2705 Metatranscriptomic reconstruction reveals RNA viruses with the potential to shape carbon cycling in soil

Starr, E. P.; Nuccio, E. E.; Pett-Ridge, J.; Banfield, J. F.; Firestone, M. K.

10.1101/597468 — microbiology — Posted on 2019-04-04

2706 Deficiency in the autophagy modulator Dram1 exacerbates pyroptotic cell death of Mycobacteria-infected macrophages

Zhang, R.; Varela, M.; Forn-Cuni, G.; Torraca, V.; van der Vaart, M.; Meijer, A.

10.1101/599266 — immunology — Posted on 2019-04-04

2707 RNAi screen reveals a role for PACSIN2 and caveolins during bacterial cell-to-cell spread

Sanderlin, A.; Vondrak, C.; Scricco, A.; Fedrigo, I.; Ahyong, V.; Lamason, R.

10.1101/599795 — cell biology — Posted on 2019-04-04

2708 Renewal theory provides a universal quantitative framework to characterise the continuous regeneration of rotational events in cardiac fibrillation

Dharmaprani, D.; Schopp, M.; Kuklik, P.; Chapman, D.; Lahiri, A.; Dykes, L.; Xiong, F.; Aguilar, M.; Strauss, B.; Mitchell, L.; Pope, K.; Meyer, C.; Willems, S.; Akar, F. G.; Nattel, S.; McGavigan, A. G.; Ganesan, A. N.

10.1101/599142 — physiology — Posted on 2019-04-04

2709 Creating a neuroprosthesis for active tactile exploration of textures

O'Doherty, J.; Shokur, S.; Medina, L. E.; Lebedev, M. A.; Nicolelis, M. A. L.

10.1101/594994 — neuroscience — Posted on 2019-04-04

2710 Disambiguating the role of blood flow and global signal with Partial Information Decomposition

Colenbier, N.; Van de Steen, F.; Uddin, L.; Poldrack, R.; Calhoun, V.; Marinazzo, D.

10.1101/596247 — neuroscience — Posted on 2019-04-04

2711 Peax: Interactive Visual Pattern Search in Sequential Data Using Unsupervised Deep Representation Learning

Lekschas, F.; Peterson, B.; Haehn, D.; Ma, E.; Gehlenborg, N.; Pfister, H.

10.1101/597518 — genomics — Posted on 2019-04-04

2712 Analysis of 19 Heliconiine Butterflies Shows Rapid TE-based Diversification and Multiple SINE Births and Deaths

Ray, D. A.; Grimshaw, J. R.; Halsey, M. K.; Korstian, J. M.; Osmanski, A. B.; Sullivan, K. A.; Wolf, K. A.; Reddy, H.; Foley, N.; Stevens, R. D.; Knisbacher, B.; Levy, O.; Counterman, B.; Edelman, N. B.; Mallet, J.

10.1101/596502 — evolutionary biology — Posted on 2019-04-04

2713 Pan-Cancer Exploration of mRNA Mediated Dysregulated Pathways in the Cancer Genomics Cloud

Linan, M.; Wang, J.; Dinu, V.

10.1101/599225 — bioinformatics — Posted on 2019-04-04

2714 Disentangling a Complex Response in Cell Reprogramming and Probing the Waddington Landscape by Automatic Construction of Petri Nets

Raetzel, V.; Werthmann, B.; Haas, M.; Strube, J.; Marwan, W.

10.1101/599191 — systems biology — Posted on 2019-04-04

2715 Novel characterization of peptidergic release from prefrontal cortical somatostatin neurons

Dao, N. C.; Brockway, D. F.; Crowley, N. A.

10.1101/599829 — neuroscience — Posted on 2019-04-04

2716 Measuring the relationship between sleep, physical activity and cognition

Swirski, M.; Shaikh, N.; Chinner, A.; Gaaikema, E.; Coulthard, E.

10.1101/599092 — neuroscience — Posted on 2019-04-04

2717 Hippocampal morphology and cytoarchitecture in the 3D BigBrain

DeKraker, J.; Lau, J. C.; Ferko, K. M.; Khan, A.; Kohler, S.

10.1101/599571 — neuroscience — Posted on 2019-04-04

2718 Regulation of adenylyl cyclase 5 in striatal neurons confers the ability to detect coincident neuromodulatory signals

Bruce, N. J.; Narzi, D.; Trpevski, D.; van Keulen, S. C.; Nair, A. G.; Roethlisberger, U.; Wade, R. C.; Carloni, P.; Hellgren Kotaleski, J.

10.1101/597096 — neuroscience — Posted on 2019-04-04

2719 Modeling Bottom-Up and Top-Down Attention with a Neurodynamic Model of V1

Berga, D.; Otazu, X.

10.1101/590174 — neuroscience — Posted on 2019-04-04

2720 In silico evidence of unique behaviors of methionine in an in-register parallel beta-sheet amyloid, suggestive of possible contribution to strain diversity of amyloids.

Otaki, H.; Taguchi, Y.; Nishida, N.

10.1101/596742 — molecular biology — Posted on 2019-04-04

2721 Single-cell transcriptomics of the naked mole-rat reveals unexpected features of mammalian immunity

Hilton, H. G.; Rubinstein, N. D.; Janki, P.; Ireland, A. T.; Bernstein, N.; Wright, K. M.; Finkle, D.; Martin-McNulty, B.; Roy, M.; Smith, M.; Imai, D. M.; Jojic, V.; Buffenstein, R.

10.1101/597195 — immunology — Posted on 2019-04-04

2722 Linking Allele-Specific Expression And Natural Selection In Wild Populations

Laso-Jadart, R.; Sugier, K.; Petit, E.; Labadie, K.; Peterlongo, P.; Ambroise, C.; Wincker, P.; Jamet, J.-L.; Madoui, M.-A.

10.1101/599076 — genomics — Posted on 2019-04-04

2723 Influence of neighboring small sequence variants on functional impact prediction

Baasner, J.-S.; Howard, D.; Pucker, B.

10.1101/596718 — genomics — Posted on 2019-04-04

2724 SSD1 suppresses phenotypes induced by the lack of Elongator-dependent tRNA modifications

Xu, F.; Bystrom, A.; Johansson, M.

10.1101/596197 — genetics — Posted on 2019-04-04

2725 Hybridization preceded radiation in diploid wheats

Huynh, S.; Marcussen, T.; felber, F.; Parisod, C.

10.1101/599068 — evolutionary biology — Posted on 2019-04-04

2726 Predicting coexistence in experimental ecologicalcommunities

Maynard, D. S.; Miller, Z. R.; Allesina, S.

10.1101/598326 — ecology — Posted on 2019-04-04

2727 EpiAlign: an alignment-based bioinformatic tool for comparing chromatin state sequences

Ge, X.; Zhang, H.; Xie, L.; Li, W. V.; Kwon, S. B.; Li, J. J.

10.1101/566299 — bioinformatics — Posted on 2019-04-04

2728 Predicting gait adaptations due to ankle plantarflexor muscle weakness and contracture using physics-based musculoskeletal simulations

Ong, C. F.; Geijtenbeek, T.; Hicks, J. L.; Delp, S. L.

10.1101/597294 — bioengineering — Posted on 2019-04-04

2729 Population productivity of wedgefishes, guitarfishes, and banjo rays: inferring the potential for recovery

D'Alberto, B. M.; Carlson, J. K.; Pardo, S. A.; Simpfendorfer, C. A.

10.1101/584557 — zoology — Posted on 2019-04-04

2730 Identification and characterization of OmpT-like proteases in uropathogenic Escherichia coli clinical isolates

Desloges, I.; Taylor, J. A.; Leclerc, J.-M.; Brannon, J. R.; Portt, A.; Spencer, J. D.; Dewar, K.; Marczynski, G. T.; Manges, A.; Gruenheid, S.; Le Moual, H.; Thomassin, J.-L.

10.1101/594564 — microbiology — Posted on 2019-04-04

2731 BCG-induced T cells shape Mycobacterium tuberculosis infection before reducing the bacterial burden

Delahaye, J. L.; Gern, B. H.; Cohen, S. B.; Plumlee, C. R.; Shafiani, S.; Gerner, M. Y.; Urdahl, K. B.

10.1101/590554 — immunology — Posted on 2019-04-04

2732 OPENANNO: annotating genomic regions with chromatin accessibility

Chen, S.; Wang, Y.; Jiang, R.

10.1101/596627 — bioinformatics — Posted on 2019-04-04

2733 An inexpensive wireless video recording system for continuous behavioral observations

Weber, W. D.; Fisher, H. S.

10.1101/596106 — animal behavior and cognition — Posted on 2019-04-04

2734 Nutritional ecology provides insights into competitive interactions between closely-related marten species

Gazzola, A.; Balestrieri, A.

10.1101/599084 — zoology — Posted on 2019-04-04

2735 An inactivation switch enables rhythms in a Neurospora clock model

Upadhyay, A.; Brunner, M.; Herzel, H.

10.1101/599506 — systems biology — Posted on 2019-04-04

2736 Unique Neurophysiological Vulnerability of Visual Attention Networks to Acute Inflammation

Balter, L. J.; Bosch, J. A.; Aldred, S.; Drayson, M. T.; Veldhuijzen van Zanten, J. J.; Higgs, S.; Raymond, J. E.; Mazaheri, A.

10.1101/599159 — neuroscience — Posted on 2019-04-04

2737 RUNX1 safeguards the identity of the fetal ovary through an interplay with FOXL2

Nicol, B.; Grimm, S. A.; Chalmel, F.; Lecluze, E.; Pannetier, M.; Pailhoux, E.; Dupin-De-Beyssat, E.; Guiguen, Y.; Capel, B.; Yao, H.

10.1101/598607 — developmental biology — Posted on 2019-04-04

2738 The emergence of sequence-dependent structural motifs in stretched, torsionally constrained DNA

Shepherd, J. W.; Greenall, R. J.; Probert, M. I. J.; Noy, A. C.; Leake, M.

10.1101/599480 — biophysics — Posted on 2019-04-04

2739 Binning unassembled short reads based on k-mer covariance in a sparse coding framework

Kyrgyzov, O.; Prost, V.; Gazut, S.; Farcy, B.; Bruls, T.

10.1101/599332 — bioinformatics — Posted on 2019-04-04

2740 Tuning the affinity of tandem calponin homology domains

Harris, A. R.; Belardi, B.; Jreij, P.; Wei, K.; Bausch, A.; Fletcher, D. A.

10.1101/598359 — biochemistry — Posted on 2019-04-04

2741 Printability study of metal ion crosslinked PEG-catechol based inks

Włodarczyk-Biegun, M. K.; Paez, J. I.; Villiou, M.; Feng, J.; del Campo, A.

10.1101/599290 — biochemistry — Posted on 2019-04-04

2742 The discrimination of tactile speed in absence of texture elements: Role of deformation and vibratory cues

Moscatelli, A.; Ryan, C. P.; Cosentino, L.; Ernst, M. O.; Lacquaniti, F.

10.1101/599522 — neuroscience — Posted on 2019-04-04

2743 Three-phase transitions to reproductive isolation: The roles of utilization mismatch and residual selection

Meszena, G.; Dieckmann, U.

10.1101/595082 — evolutionary biology — Posted on 2019-04-04

2744 Nanog regulates Pou3f1 expression and represses anterior fate at the exit from pluripotency.

Barral, A.; Rollan, I.; Sanchez-Iranzo, H.; Jawaid, W.; Badia-Careaga, C.; Menchero, S.; Gomez-Rodriguez, M.; Torroja, C.; Sanchez-Cabo, F.; Gottgens, B.; Manzanares, M.; Sainz de Aja, J.

10.1101/598656 — developmental biology — Posted on 2019-04-04

2745 Time resolved quantitative phosphoproteomics reveals distinct patterns of SHP2 dependence in EGFR signaling

Vemulapalli, V.; Chylek, L.; Erickson, A.; LaRochelle, J.; Subramanian, K.; Mohseni, M.; LaMarche, M.; Acker, M. G.; Sorger, P. K.; Gygi, S. P.; Blacklow, S. C.

10.1101/598664 — cell biology — Posted on 2019-04-04

2746 Multiplexed 129Xe HyperCEST MRI detection of genetically-reconstituted bacterial protein nanoparticles in human cancer cells.

Mizushima, R.; Inoue, K.; Iwane, A. H.; Kimura, A.; Watanabe, T. M.

10.1101/599118 — biophysics — Posted on 2019-04-04

2747 Negative Binomial Additive Model for RNA-Seq Data Analysis

Ren, X.; Kuan, P. F.

10.1101/599811 — bioinformatics — Posted on 2019-04-04

2748 Improved bacteria population structure analysis on thousands of genomes using unsupervised methods

Schlum, K. A.; Jun, S.-R.; Udaondo, Z.; Ussery, D. W.; Emrich, S. J.

10.1101/599944 — bioinformatics — Posted on 2019-04-04

2749 Brain imaging correlates of general intelligence in UK Biobank

Cox, S. R.; Ritchie, S. J.; Fawns-Ritchie, C.; Tucker-Drob, E. M.; Deary, I. J.

10.1101/599472 — neuroscience — Posted on 2019-04-04

2750 Epigenetic gestational age and trajectories of weight and height during childhood: a prospective cohort study

Bright, H. D.; Howe, L. D.; Khouja, J. N.; Simpkin, A. J.; Suderman, M.; O'Keeffe, L. M.

10.1101/599738 — genomics — Posted on 2019-04-04

Llabres, S.; Zachariae, U.

10.1101/598672 — biophysics — Posted on 2019-04-04

2752 Vireo: Bayesian demultiplexing of pooled single-cell RNA-seq data without genotype reference

Huang, Y.; McCarthy, D. J.; Stegle, O.

10.1101/598748 — bioinformatics — Posted on 2019-04-04

2753 A Truly Injectable Neural Stimulation Electrode Made from an In-Body Curing Polymer/Metal Composite

10.1101/584995 — bioengineering — Posted on 2019-04-04

2754 Decreased confidence in loss-avoidance contexts is a primary meta-cognitive bias of human reinforcement learning

Ting, C.-C.; Palminteri, S.; Engelmann, J. B.; Lebreton, M.

10.1101/593368 — animal behavior and cognition — Posted on 2019-04-04

2755 Modern clinical Mtb strains leverage the type I IFN pathway for a pro-inflammatory response in the host

Shankaran, D.; Arumugam, P.; Gandotra, S.; Rao, V. K.

10.1101/594655 — immunology — Posted on 2019-04-04

2756 Ageing in house sparrows is insensitive to environmental effects

Simons, M.; Winney, I.; Girndt, A.; Rees, M.; Nakagawa, S.; Schroeder, J.; Burke, T.

10.1101/598284 — evolutionary biology — Posted on 2019-04-04

2757 A three-sample test for introgression

Hahn, M. W.; Hibbins, M. S.

10.1101/594333 — evolutionary biology — Posted on 2019-04-04

2758 De novo design of proteins with two isoenergetic but structurally divergent ground states

Wei, K. Y.; Moschidi, D.; Bick, M. J.; Nerli, S.; McShan, A. C.; Carter, L. P.; Huang, P.-S.; Fletcher, D. A.; Sgourakis, N. G.; Boyken, S. E.; Baker, D.

10.1101/597161 — biochemistry — Posted on 2019-04-04

2759 Enabling large-scale genome editing by reducing DNA nicking

Smith, C. J.; Castanon, O.; Said, K.; Volf, V.; Khoshakhlagh, P.; Hornick, A.; Ferreira, R.; Wu, C.-T.; Güell, M.; Garg, S.; Myllykallio, H.; Church, G. M.

10.1101/574020 — synthetic biology — Posted on 2019-04-04

2760 Reduced prediction error responses in high- as compared to low-uncertainty musical contexts

Quiroga-Martinez, D. R.; Hansen, N. C.; Hoejlund, A.; Pearce, M.; Brattico, E.; Vuust, P.

10.1101/422949 — neuroscience — Posted on 2019-04-04

2761 The rs6505162 C>A polymorphism in the miRNA-423 gene exhibits a protective element of coronary artery in a southern Chinese population with Kawasaki disease

Li, J.; Wang, J.; Su, X.; Jiang, Z.; Gu, X.; Rong, X.; Qiu, H.; Zeng, L.; Zheng, H.; Gu, X.; Chu, M.

10.1101/596783 — genetics — Posted on 2019-04-04

2762 Novel pipeline of high-frequency neoantigens heathy donor-based validation in breast cancer

li, Q.; ying, H.; duan, L.; geng, L.; mei, L.; ting, A.; li, L.; le, C.; bo, L.

10.1101/596908 — cancer biology — Posted on 2019-04-04

2763 A two-enzyme adaptive unit in bacterial folate metabolism

Schober, A. F.; Mathis, A. D.; Ingle, C.; Park, J. O.; Chen, L.; Rabinowitz, J. D.; Junier, I.; Rivoire, O.; Reynolds, K. A.

10.1101/120006 — systems biology — Posted on 2019-04-04

2764 Deep learning based brain age prediction uncovers associated sequence variants

Jonsson, B. A.; Bjornsdottir, G.; Thorgeirsson, T.; Ellingsen, L. M.; Walters, G. B. B.; Gudbjartsson, D. F.; Stefansson, H.; Stefansson, K.; Ulfarsson, M. O.

10.1101/595801 — neuroscience — Posted on 2019-04-04

2765 A new massively-parallel transposon mutagenesis approach comparing multiple datasets identifies novel mechanisms of action and resistance to triclosan

Yasir, M.; Turner, K.; bastkowski, s.; Page, A.; Telatin, A.; Phan, M.-D.; Monahan, L.; Darling, A. E.; Webber, M.; Charles, I.

10.1101/596833 — microbiology — Posted on 2019-04-04

2766 Anti-HIV-1 Activity of Crocodylus mindorensis (Philippine crocodile) serum in cell-free and cell-associated virus interactions to human peripheral blood mononuclear cells

Hinay, A. A.; Cadotdot, N. T.; Tablizo, M.

10.1101/596775 — immunology — Posted on 2019-04-04

2767 Integrated RNA and metabolite profiling of urine liquid biopsies for prostate cancer biomarker discovery

Lee, B.; Mahmud, I.; Marchica, J.; Derezinski, P.; Qi, F.; Wang, F.; Joshi, P.; Valerio, F.; Rivera, I.; Patel, V.; Pavlovich, C. P.; Garrett, T.; Schroth, G. P.; Sun, Y.; Perera, R. J.

10.1101/599514 — cancer biology — Posted on 2019-04-04

2768 Neural and computational mechanisms of analogical reasoning

Chiang, J.; Peng, Y.; Lu, H.; Holyoak, K.; Monti, M.

10.1101/596726 — neuroscience — Posted on 2019-04-04

2769 The full-length transcriptome of C. elegans using direct RNA sequencing

Roach, N. P.; Sadowski, N.; Alessi, A. F.; Timp, W.; Taylor, J.; Kim, J. K.

10.1101/598763 — genomics — Posted on 2019-04-04

2770 Antitumor Activities and Cellular Changes Induced by TrkB Inhibition in Medulloblastoma

Thomaz, A.; Pinheiro, K. d. V.; Souza, B. K.; Gregianin, L.; Brunetto, A. L.; Brunetto, A. T.; de Farias, C. B.; Jaeger, M. d. C.; Ramaswamy, V.; Nor, C.; Taylor, M. D.; Roesler, R.

10.1101/566000 — cancer biology — Posted on 2019-04-04

2771 Probing Ligand and Cation Binding Sites in G-Quadruplex Nucleic Acids by Mass Spectrometry and Electron Photodetachment Dissociation Sequencing

Paul, D.; Marchand, A.; Verga, D.; Bombard, S.; Teulade-Fichou, M.-P.; Rosu, F.; Gabelica, V.

10.1101/563627 — biophysics — Posted on 2019-04-04

2772 On the prediction of protein abundance from RNA

Magnusson, R.; Rundquist, O.; Kim, M. J.; Hellberg, S.; Na, C. H.; benson, m.; Gomez-Cabrero, D.; Kockum, I. S.; Tegner, J.; Piehl, F.; Jagodic, M.; Mellergard, J.; Altafini, C.; Ernerudh, J.; Jenmalm, M. C.; Nestor, C. E.; Kim, M.-S.; Gustafsson, M.

10.1101/599373 — bioinformatics — Posted on 2019-04-04

2773 Comparing the functional structure of neural networks from representational similarity analysis with those from functional connectivity and univariate analyses

Pillet, I.; Op de Beeck, H.; Lee Masson, H.

10.1101/487199 — neuroscience — Posted on 2019-04-04

2774 Single amino acid changes decouple two opposite activities of a viral auxiliary replication protein

Guo, Q.; Zhang, S.; Sun, R.; Yao, X.; Tatineni, S.; Meulia, T.; Qu, F.

10.1101/596767 — molecular biology — Posted on 2019-04-04

2775 Genomic analysis reveals selection signatures of Yucatan miniature pig on its X chromosome during domestication

Zhang, W.; Yin, Z.; Ding, Y.; Zhang, X.; Wu, X.; Wang, Y.; Yang, M.

10.1101/596387 — genomics — Posted on 2019-04-04

2776 Bayesian Variable Selection with a Pleiotropic Loss Function in Mendelian Randomization

Gkatzionis, A.; Burgess, S.; Conti, D.; Newcombe, P. J.

10.1101/593863 — genetics — Posted on 2019-04-04

2777 Contraction of the ROS scavenging enzyme glutathione S-transferase gene family in cetaceans

Tian, R.; Seim, I.; Ren, W.; Xu, S.; Yang, G.

10.1101/596395 — evolutionary biology — Posted on 2019-04-04

2778 Visual and non-visual properties of filters manipulating short-wavelength light

Spitschan, M.; Lazar, R.; Cajochen, C.

10.1101/596957 — neuroscience — Posted on 2019-04-04

2779 Trichoplein controls endothelial cell function by regulating autophagy

Martello, A.; Lauriola, A.; Mellis, D.; Parish, E.; Dawson, J. C.; Imrie, L.; Vidmar, M.; Gammoh, N.; Mitic, T.; Brittan, M.; Mills, N.; Carragher, N.; D'Arca, D.; Caporali, A.

10.1101/595702 — molecular biology — Posted on 2019-04-04

2780 Mitochondria form cholesterol tethered contact sites with the Nucleus to regulate retrograde response

Desai, R.; East, D. A.; Hardy, L.; Crosby, J.; Rigon, M.; Faccenda, D.; Alvarex, M. S.; Singh, A.; Mainenti, M.; Hussey, L. K.; Bentham, R.; Szabadkai, G.; Zappulli, V.; Dhoot, G.; Romano, L. E.; Dong, X.; Hamacher-Brady, A.; Chapple, P.; Fleck, R. A.; Vizcay-Barrena, G.; Smith, K.; Campanella, M.

10.1101/445411 — cell biology — Posted on 2019-04-04

2781 A Model for the Peak-Interval Task Based on Neural Oscillation-Delimited States

Tarraf Varella, T.; Reyes, M. B.; Caetano, M. S.; De Camargo, R. Y.

10.1101/448688 — animal behavior and cognition — Posted on 2019-04-04

2782 Multiscale Adaptive Gabor Expansion (MAGE): Improved Detection of Transient Oscillatory Burst Amplitude and Phase

Canolty, R. T.; Womelsdorf, T.

10.1101/369116 — neuroscience — Posted on 2019-04-04

2783 Active mode of excretion across digestive tissues predates the origin of excretory organs

Andrikou, C.; Thiel, D.; Ruiz-Santiesteban, J. A.; Hejnol, A.

10.1101/136788 — evolutionary biology — Posted on 2019-04-04

2784 Visualizing Structure and Transitions for Biological Data Exploration

Moon, K. R.; van Dijk, D.; Wang, Z.; Gigante, S.; Burkhardt, D.; Chen, W.; Yim, K.; van den Elzen, A.; Hirn, M. J.; Coifman, R. R.; Ivanova, N. B.; Wolf, G.; Krishnaswamy, S.

10.1101/120378 — bioinformatics — Posted on 2019-04-04

2785 Pregnancy-associated plasma protein-aa supports hair cell survival by regulating mitochondrial function

Wolman, M. A.; Alassaf, M.; Daykin, E. C.; Mathiaparanam, J.

10.1101/598029 — cell biology — Posted on 2019-04-04

2786 How the Avidity of Polymerase Binding to the -35/-10 Promoter Sites Affects Gene Expression

Einav, T.; Phillips, R.

10.1101/597989 — biophysics — Posted on 2019-04-04

2787 Optimal gene selection for cell type discrimination in single cell analyses

Dumitrascu, B.; Villar, S.; Mixon, D. G.; Engelhardt, B. E.

10.1101/599654 — genomics — Posted on 2019-04-04

2788 The RNA binding protein DAZL functions as repressor and activator of maternal mRNA translation during oocyte maturation

Yang, C.; Rajkovic, G.; Daldello, E. M.; Luong, X. G.; Chen, J.; Conti, M.

10.1101/598805 — developmental biology — Posted on 2019-04-04

2789 Effects of mesotocin on social bonding in pinyon jays

Duque, J. F.; Rasmussen, T.; Rodriguez, A.; Stevens, J. R.

10.1101/599555 — animal behavior and cognition — Posted on 2019-04-04

2790 The Genomics of Selfing in Maize (Zea mays ssp. mays): Catching Purging in the Act

Roessler, K.; Muyle, A.; Diez, C. M.; Gaut, G. R.; Bousios, A.; Stitzer, M.; Seymour, D. K.; Doebley, J. F.; Liu, Q.; Gaut, B. S.

10.1101/594812 — genomics — Posted on 2019-04-04

2791 Action Potential Propagation and Synchronisation inMyelinated Axons

Schmidt, H.; Knösche, T.

10.1101/599746 — neuroscience — Posted on 2019-04-04

2792 Knowledge, attitudes and practices of hypertension in a community based cross sectional study done in Ward 14, Gwanda District, Matebeleland South, Zimbabwe

Chimberengwa, P. T.; Naidoo, M.

10.1101/599688 — epidemiology — Posted on 2019-04-04

2793 Predicting sediment and nutrient concentrations from high-frequency water-quality data

Leigh, C.; Kandanaarachchi, S.; McGree, J. M.; Hyndman, R. J.; Alsibai, O.; Mengersen, K.; Peterson, E. E.

10.1101/599712 — ecology — Posted on 2019-04-04

2794 Modelling marine larval dispersal: a cautionary deep-sea tale for ecology and conservation

Ross, R. E.; Nimmo-Smith, W. A. M.; Torres, R.; Howell, K. L.

10.1101/599696 — ecology — Posted on 2019-04-04

2795 Bone regeneration in Ds-Red pig calvarial defect using allogenic transplantation of EGFP-pMSCs - a comparison of host cells and seeding cells in the scaffold

Hsieh, M.-k.; Wu, C.-J.; Su, X.-C.; Chen, Y.-C.; Tsai, T.-T.; Niu, C.-C.; Lai, P.-L.; Wu, S.-C.

10.1101/599670 — cell biology — Posted on 2019-04-04

2796 Machine learning to predict microbial community functions: An analysis of dissolved organic carbon from litter decomposition.

Thompson, J.; Johansen, R.; Dunbar, J.; Munsky, B.

10.1101/599704 — bioinformatics — Posted on 2019-04-04

2797 How the liver contributes to stomach warming in the endothermic white shark Carcharodon carcharias

Bernvi, D. C.; Cliff, G.

10.1101/599639 — zoology — Posted on 2019-04-04

2798 Analysis of glue line and correlations between anatomical characteristics of Eucalyptus grandis x Eucalyptus urophylla glued-laminated timber

Oliveira, R. G. E.; Goncalves, F. G.; Segundinho, P. G. d. A.; Oliveira, J. T. d. S.; Paes, J. B.; Chaves, I. L. S.; Brito, A. S.

10.1101/599662 — plant biology — Posted on 2019-04-04

2799 Gut microbiome features associated with Clostridium difficile colonization in puppies

Berry, A.; Barnhart, D.; Kelly, B. J.; Kelly, D. J.; Beiting, D. P.; Baldassano, R. N.; Redding, L.

10.1101/599647 — epidemiology — Posted on 2019-04-04

2800 CiiiDER: a new tool for predicting and analysing transcription factor binding sites

Gearing, L. J.; Cumming, H. E.; Chapman, R.; Finkel, A. M.; Woodhouse, I. B.; Luu, K.; Gould, J. A.; Forster, S. C.; Hertzog, P. J.

10.1101/599621 — bioinformatics — Posted on 2019-04-04

2801 The Long-run Effects of Secondary School Track Assignment

Borghans, L.; Diris, R.; Smits, W.; De Vries, J.

10.1101/599605 — scientific communication and education — Posted on 2019-04-04

2802 Bulked segregant analysis RNA-seq (BSR-Seq) validated a stem resistance locus in Aegilops umbellulata, a wild relative of wheat

Edae, E. A.; Rouse, M.

10.1101/599597 — genomics — Posted on 2019-04-04

2803 NF-YA Transcriptionally Activates the Expression of SOX2 in Cervical Cancer Stem Cells

Yang, W.-T.; Zhao, Z.-X.; Li, B.; Zheng, P.-S.

10.1101/599613 — cancer biology — Posted on 2019-04-04

2804 Pre-Settlement Forests around Puget Sound: Eyewitness Evidence

Schroeder, T.

10.1101/592733 — plant biology — Posted on 2019-04-04

2805 methyl-ATAC-seq measures DNA methylation at accessible chromatin

Spektor, R.; Tippens, N. D.; Mimoso, C. A.; Soloway, P. D.

10.1101/445486 — genomics — Posted on 2019-04-04

2806 A Vibrio cholerae BolA-like protein is required for proper cell shape and cell envelope integrity

Fleurie, A.; Zoued, A.; Alvarez, L.; Hines, K. M.; Cava, F.; Xu, L.; Davis, B. M.; Waldor, M. K.

10.1101/597369 — microbiology — Posted on 2019-04-04

2807 Diverse communities behave like typical random ecosystems

Cui, W.; Marsland, R.; Mehta, P.

10.1101/596551 — ecology — Posted on 2019-04-04

2808 Proposal for a Global Adherence Scale for Acute Conditions (GASAC): a prospective cohort study in two Emergency Departments

Sustersic, M.; Gauchet, A.; Duvert, A.; Gonnet, L.; Foote, A.; Vermorel, C.; Allenet, B.; Bosson, J.-L.

10.1101/598409 — epidemiology — Posted on 2019-04-04

2809 The Alzheimer’s Disease Metabolome: Effects of Sex and APOE ε4 genotype

Arnold, M.; Nho, K.; Kueider-Paisley, A.; Massaro, T.; Brauner, B.; Mahmoudiandehkordi, S.; Louie, G.; Moseley, M. A.; Thompson, J. W.; St John-Williams, L.; Tenebaum, J. D.; Blach, C.; Chang, R.; Brinton, R. D.; Baillie, R.; Han, X.; Trojanowski, J. Q.; Shaw, L. M.; Weiner, M. W.; Trushina, E.; Toledo, J. B.; Krumsiek, J.; Doraiswamy, P. M.; Saykin, A. J.; Kaddurah-Daouk, R.; Kastenmuller, G.; Alzheimers Disease Neuroimaging Initiative, ; Alzheimers Disease Metabolomics Consortium,

10.1101/585455 — bioinformatics — Posted on 2019-04-04

2810 Parkin-mediated ubiquitination contributes to the constitutive turnover of mitochondrial fission factor (Mff)

Lee, L.; Seager, R.; Nakamura, Y.; Wilkinson, K.; Henley, J.

10.1101/553859 — cell biology — Posted on 2019-04-04

2811 TDP-43 proteinopathy impairs neuronal mRNP granule mediated postsynaptic local translation and mRNA metabolism

Wong, C.-E.; Tsai, K.-J.

10.1101/589416 — neuroscience — Posted on 2019-04-04

2812 CGGBP1 regulates chromatin barrier activity and CTCF occupancy at repeats

Patel, D. K.; Patel, M.; Singh, U.

10.1101/593137 — genomics — Posted on 2019-04-04

2813 Comparative analysis of novel MGISEQ-2000 sequencing platform vs Illumina HiSeq 2500 for whole-genome sequencing

Gorbachev, A.; Kulemin, N.; Naumov, V.; Belova, V.; Kwon, D.; Rebrikov, D.; Korostin, D.

10.1101/577080 — genomics — Posted on 2019-04-04

2814 A triple-hybrid cross reveals a new hybrid incompatibility locus between D. melanogaster and D. sechellia

Cooper, J. C.; Guo, P.; Bladen, J.; Phadnis, N.

10.1101/590588 — evolutionary biology — Posted on 2019-04-04

2815 The structure of species discrimination signals across a primate radiation

Winters, S.; Allen, W. L.; Higham, J. P.

10.1101/574558 — evolutionary biology — Posted on 2019-04-04

2816 Single particle diffusion characterization by deep learning

Granik, N.; Nehme, E.; Weiss, L. E.; Levin, M.; Chein, M.; Perlson, E.; Roichman, Y.; Shechtman, Y.

10.1101/588533 — biophysics — Posted on 2019-04-04

2817 Cell BLAST: Searching large-scale scRNA-seq databases via unbiased cell embedding

Cao, Z.-J.; Wei, L.; Lu, S.; Yang, D.-C.; Gao, G.

10.1101/587360 — bioinformatics — Posted on 2019-04-04

2818 High-Speed Automatic Characterization of Rare Events in Flow Cytometric Data

Qi, Y.; Fang, Y.; Sinclair, D. R.; Guo, S.; Alberich-Jorda, M.; Lu, J.; Tenen, D. G.; Kharas, M. G.; Pyne, S.

10.1101/591644 — bioinformatics — Posted on 2019-04-04

2819 DRAFT - Robotic automation of production and the recovery of cell spheroids

Langer, K.; Joensson, H.

10.1101/552687 — bioengineering — Posted on 2019-04-04

2820 Interacting Networks Associated with Parent-of-Origin Effects on Metabolic Traits

Macias-Velasco, J. F.; St.Pierre, C. L.; Wayhart, J. P.; Yin, L.; Spears, L.; Funai, K.; Semenkovich, C. F.; Lawson, H. A.

10.1101/579748 — systems biology — Posted on 2019-04-04

2821 Characterization of novel Chrysosporium morrisgordonii sp. nov., from bat white-nose syndrome (WNS) affected mines, northeastern United States

Zhang, T.; Ren, P.; Li, X.; Chaturvedi, S.; Chaturvedi, V.

10.1101/591503 — microbiology — Posted on 2019-04-04

2822 Multiple evolutionary trajectories for non-O157 Shiga toxigenic Escherichia coli

Alikhan, N.-F.; Bachmann, N. L.; Ben Zakour, N. L.; Petty, N. K.; Stanton-Cook, M.; Gawthorne, J. A.; Easton, D. M.; Mahony, T. J.; Cobbold, R.; Schembri, M. A.; Beatson, S. A.

10.1101/549998 — microbiology — Posted on 2019-04-04

2823 Quantitative Principles of cis-translational control by general mRNA sequence features in eukaryotes

Li, J. J.; Chew, G.-L.; Biggin, M. D.

10.1101/587584 — genomics — Posted on 2019-04-04

2824 Shared genetic background between children and adults with attention deficit/hyperactivity disorder

Rovira, P.; Demontis, D.; Sanchez-Mora, C.; Zayats, T.; Klein, M.; Roth Mota, N.; Weber, H.; Garcia-Martinez, I.; Pagerols, M.; Vilar, L.; Arribas, L.; Richarte, V.; Corrales, M.; Fadeuilhe, C.; Bosch, R.; Espanol Martin, G.; Almos, P.; Doyle, A. E.; Grevet, E. H.; Grimm, O.; Halmoy, A.; Hoogman, M.; Hutz, M.; Jacob, C. P.; Kittel-Schneider, S.; Knappskog, P. M.; Lundervold, A.; Rivero, O.; Rovaris, D. L.; Salatino-Oliveira, A.; Santos da Silva, B.; Svirin, E.; Sprooten, E.; Strekalova, T.; ADHD Working Group of the Psychiatric Genomics Con, ; 23andMe Research team, ; Arias-Vasquez, A.; Sonu

10.1101/589614 — genetics — Posted on 2019-04-04

2825 Characterizing the adaptive potential of north-western Pacific reef corals to empower conservation strategies: a role for seascape genomics

Selmoni, O.; Veronique, B.-L.; Lecellier, G.; Joost, S.

10.1101/588228 — evolutionary biology — Posted on 2019-04-04

2826 Distribution of iridescent colours in hummingbird communities results from the interplay between selection for camouflage and communication

Gruson, H.; Elias, M.; Parra, J. L.; Andraud, C.; Berthier, S.; Doutrelant, C.; Gomez, D.

10.1101/586362 — ecology — Posted on 2019-04-04

2827 Fog signaling has diverse roles in epithelial morphogenesis in insects

Frey, N.; Benton, M. A.; Nunes da Fonseca, R.; von Levetzow, C.; Stappert, D.; Hakeemi, M. S.; Conrads, K. H.; Pechmann, M.; Panfilio, K. A.; Lynch, J. A.; Roth, S.

10.1101/578526 — developmental biology — Posted on 2019-04-04

2828 ERK1/2 signalling dynamics promote neural differentiation by regulating the polycomb repressive complex

Semprich, C. I.; Metzis, V.; Patel, H.; Briscoe, J.; Storey, K. G.

10.1101/586719 — developmental biology — Posted on 2019-04-04

2829 CompScore: boosting structure-based virtual screening performance by incorporating docking scoring functions components into consensus scoring

Perez-Castillo, Y.; Sotomayor-Burneo, S.; Jimenes-Vargas, K.; Gonzalez-Rodriguez, M.; Cruz-Monteagudo, M.; Armijos-Jaramillo, V.; D. S. Cordeiro, M. N.; Borges, F.; Sanchez-Rodriguez, A.; Tejera, E.

10.1101/550590 — bioinformatics — Posted on 2019-04-04

2830 Pacing behaviour in laboratory macaques is an unreliable indicator of acute stress.

Poirier, C.; Oliver, C. J.; Catellano Bueno, J.; Flecknell, P.; Bateson, M.

10.1101/568378 — animal behavior and cognition — Posted on 2019-04-04

2831 Firing rate distributions in spiking networks with heterogeneous connectivity

Vegue, M.; Roxin, A.

10.1101/542456 — neuroscience — Posted on 2019-04-04

2832 An investigation into serotonergic and environmental interventions against depression in a simulated delayed reward paradigm

Porr, B.; Trew, A.; Miller, A.

10.1101/580456 — neuroscience — Posted on 2019-04-04

2833 Caveolae and scaffold detection from single molecule localization microscopy data using deep learning

Khater, I. M.; Aroca-Ouellette, S. T.; Meng, F.; Nabi, I. R.; Hamarneh, G.

10.1101/526327 — molecular biology — Posted on 2019-04-04

2834 Codon Bias Confers Stability to mRNAs via ILF2 in Humans

Hia, F.; Yang, S. F.; Shichino, Y.; Yoshinaga, M.; Murakawa, Y.; Vandenbon, A.; Fukao, A.; Fujiwara, T.; Landthaler, M.; Natsume, T.; Adachi, S.; Iwasaki, S.; Takeuchi, O.

10.1101/585992 — molecular biology — Posted on 2019-04-04

2835 Sphingomyelin is critical in organizing phosphoinositide dynamics during phagocytic uptake of Mycobacterium tuberculosis.

Niekamp, P.; Guzman, G.; Leier, H.; Rashidfarrokhi, A.; Richina, V.; Holthuis, J.; Tafesse, F. G.

10.1101/565226 — microbiology — Posted on 2019-04-04

2836 A rapid and simple method for assessing and representing genome sequences relatedness

Briand, M.; Bouzid, M.; Hunault, G.; Legeay, M.; Fischer-Le Saux, M.; Barret, M.

10.1101/569640 — genomics — Posted on 2019-04-04

2837 Advantages of genotype imputation with ethnically matched reference panel for rare variant association analyses

Kals, M.; Nikopensius, T.; Läll, K.; Pärn, K.; Sikka, T. T.; Suvisaari, J.; Salomaa, V.; Ripatti, S.; Palotie, A.; Metspalu, A.; Esko, T.; Palta, P.; Mägi, R.

10.1101/579201 — genomics — Posted on 2019-04-04

2838 Automatic structure-based NMR methyl resonance assignment in large proteins

Pritisanac, I.; Würz, J. M.; Alderson, T. R.; Güntert, P.

10.1101/538272 — biophysics — Posted on 2019-04-04

2839 Kevlar: a mapping-free framework for accurate discovery of de novo variants

Standage, D. S.; Brown, C. T.; Hormozdiari, F.

10.1101/549154 — bioinformatics — Posted on 2019-04-04

2840 Buffer Therapy in Acute Metabolic Acidosis: Effects on Acid-Base Status and Glomerular Permeability

Schnapauff, J.; Piros, D.; Rippe, A.; Bentzer, P.; Clyne, N.; Oberg, C. M.

10.1101/528521 — physiology — Posted on 2019-04-04

2841 Unbiased estimation of linkage disequilibrium from unphased data

Ragsdale, A. P.; Gravel, S.

10.1101/557488 — genetics — Posted on 2019-04-04

2842 The Pattern of Comorbidities and Multimorbidity among Colorectal Cancer Patients in Spain: CoMCoR study

LUQUE-FERNANDEZ, M. A.; Redondo-Sanchez, D.; Rodriguez-Barranco, M.; Carmona Garcia, M. C.; Marcos-Gragera, R.; Sanchez, M.-J.

10.1101/526673 — epidemiology — Posted on 2019-04-04

2843 The Genetic Basis of Transcriptional and Spatial Heterogeneity of Basal-Like Features in Pancreatic Ductal Adenocarcinoma

Hayashi, A.; Fan, J.; Chen, R.; Ho, Y.-j.; Makohon-Moore, A. P.; Zhong, Y.; Hong, J.; Sakamoto, H.; Attiyeh, M. A.; Kohutek, Z. A.; Zhang, L.; Huang, J.; Boumiza, A.; Kappagantula, R.; Baez, P.; Wood, L. D.; Hruban, R. H.; Marta, L.; Chadalavada, K.; Nanjangud, G. J.; Basturk, O.; Klimstra, D. S.; Overholtzer, M.; Iacobuzio-Donahue, C. A.

10.1101/548354 — cancer biology — Posted on 2019-04-04

2844 The human HELLS chromatin remodelling protein promotes end resection to facilitate homologous recombination within heterochromatin

Chambers, A. L.; Kollarovic, G.; Topping, C. E.

10.1101/504043 — biochemistry — Posted on 2019-04-04

2845 Social hierarchy position in female mice is associated with plasma corticosterone levels and hypothalamic gene expression

Williamson, C. M.; Lee, W.; Decasien, A. R.; Lanham, A.; Romeo, R. D.; Curley, J. P.

10.1101/529131 — animal behavior and cognition — Posted on 2019-04-04

2846 Value representations do not explain movement selectivity in DMS-projecting dopamine neurons

Lee, R. S.; Mattar, M. G.; Parker, N. F.; Witten, I. B.; Daw, N. D.

10.1101/447532 — neuroscience — Posted on 2019-04-04

2847 The relationship between gene co-expression network connectivity and phenotypic prediction sheds light at the core of the omnigenic theory

Chateigner, A.; Lesage-Descauses, M.-C.; Rogier, O.; Jorge, V.; Leple, J.-C.; Brunaud, V.; Paysant-Le Roux, C.; Soubigou-Taconnat, L.; Martin-Magniette, M.-L.; Sanchez, L.; Segura, V.

10.1101/523365 — genomics — Posted on 2019-04-04

2848 Investigating the longitudinal consistency and genetic architecture of non-cognitive skills, and their relation to educational attainment

Morris, T. T.; Davey Smith, G.; Van den Berg, G.; Davies, N. M.

10.1101/470682 — genetics — Posted on 2019-04-04

2849 Meta-population structure and the evolutionary transition to multicellularity

Rose, C. J.; Hammerschmidt, K.; Rainey, P. B.

10.1101/407163 — evolutionary biology — Posted on 2019-04-04

2850 Active mode of excretion across digestive tissues predates the origin of excretory organs

Andrikou, C.; Thiel, D.; Ruiz-Santiesteban, J. A.; Hejnol, A.

10.1101/136788 — evolutionary biology — Posted on 2019-04-04

2851 Reduced serotonin receptors and transporters in normal aging adults: a meta-analysis of PET and SPECT imaging studies

Karrer, T. M.; McLaughlin, C. L.; Guaglianone, C. P.; Samanez-Larkin, G. R.

10.1101/429266 — neuroscience — Posted on 2019-04-04

2852 Not dead yet: Diatom resting spores can survive in nature for several millennia.

Sanyal, A.; Larsson, J.; van Wirdhum, F.; Andren, T.; Moros, M.; Lonn, M.; Andren, E.

10.1101/285122 — evolutionary biology — Posted on 2019-04-04

2853 WNT4 and WNT3A activate cell autonomous Wnt signaling independent of PORCN and secretion

Rao, D. M.; Ferguson, R. L.; Bordeaux, E. K.; Yamamoto, T. M.; Bitler, B. G.; Sikora, M. J.

10.1101/333906 — cell biology — Posted on 2019-04-04

2854 Atropselective Oxidation of 2,2’,3,3’,4,6’-Hexachlorobiphenyl (PCB 132) to Hydroxylated Metabolites by Human Liver Microsomes and Its Implications for PCB 132 Neurotoxicity

Uwimana, E.; Li, X.; Yeung, C.; Patterson, E. V.; Lehmler, H.-J.

10.1101/373837 — pharmacology and toxicology — Posted on 2019-04-04

2855 Coherent neuronal dynamics driven by optogenetic stimulation in the primate brain

Shewcraft, R. A.; Dean, H. L.; Hagan, M. A.; Fabiszak, M. M.; Wong, Y. T.; Pesaran, B.

10.1101/437970 — neuroscience — Posted on 2019-04-04

2856 Pattern-Driven Navigation in 2D Multiscale Visualizations with Scalable Insets

Lekschas, F.; Behrisch, M.; Bach, B.; Kerpedjiev, P.; Gehlenborg, N.; Pfister, H.

10.1101/301036 — bioinformatics — Posted on 2019-04-04

2857 Accurate estimation of SNP-heritability from biobank-scale data irrespective of genetic architecture

Hou, K.; Burch, K. S.; Majumdar, A.; Shi, H.; Mancuso, N.; Wu, Y.; Sankararaman, S.; Pasaniuc, B.

10.1101/526855 — genomics — Posted on 2019-04-03

2858 An efficient timer and sizer of biomacromolecular motions

Chan, J.; Lin, H.-R.; Takemura, K.; Chang, K.-C.; Chang, Y.-Y.; Joti, Y.; Kitao, A.; Yang, L.-W.

10.1101/384511 — biophysics — Posted on 2019-04-03

2859 Dental calculus as a tool to study the evolution of the oral microbiome in mammals

Brealey, J. C.; Leitao, H. G.; Xu, W.; Dalen, L.; Guschanski, K.

10.1101/596791 — evolutionary biology — Posted on 2019-04-03

2860 Y-chromosome haplogroups from Hun, Avar and conquering Hungarian period nomadic people of the Carpathian Basin

Neparaczki, E.; Maroti, Z.; Kalmar, T.; Maar, K.; Nagy, I.; Latinovics, D.; Kustar, A.; Palfi, G.; Molnar, E.; Marcsik, A.; Balogh, C.; Lorinczy, G.; Gal, S.; Tomka, P.; Kovacsoczy, B.; Kovacs, L.; Rasko, I.; Torok, T.

10.1101/597997 — genetics — Posted on 2019-04-03

2861 A Single-cell Transcriptomic Atlas of the Developing Chicken Limb

Feregrino, C.; Sacher, F.; Parnas, O.; Tschopp, P.

10.1101/598227 — developmental biology — Posted on 2019-04-03

2862 A novel high-throughput molecular counting method with single base-pair resolution enables accurate single-gene NIPT

Tsao, D. S.; Silas, S.; Landry, B. P.; Itzep, N.; Nguyen, A. B.; Kanne, C. K.; Sheehan, V. A.; Sharma, R.; Shukla, R.; Arora, P. N.; Atay, O.

10.1101/597732 — genetics — Posted on 2019-04-03

2863 Fast and unbiased purification of RNA-protein complexes after UV cross-linking

Urdaneta, E. C.; Beckmann, B. M.

10.1101/597575 — biochemistry — Posted on 2019-04-03

2864 Conspecific larval extracts along with biotoxin to attract-and-kill mosquitoes

Faierstein, G.; Lu, W.; Sena, A.; Barbosa, R.; Leal, W.

10.1101/596643 — ecology — Posted on 2019-04-03

2865 FGF/MAPK signaling pathway regulates the genome-wide occupancy of Polycomb Repressive Complex 2 in murine embryonic stem cells

Aljazi, M. B.; Gao, Y.; Wu, Y.; Mias, G. I.; He, J.

10.1101/597674 — genetics — Posted on 2019-04-03

2866 Disease-associated mutations hyperactivate KIF1A motility and anterograde axonal transport of synaptic vesicle precursors

Chiba, K.; Min, C.; Arai, S.; Hashimoto, K.; McKenney, R. J.; Niwa, S.

10.1101/597906 — cell biology — Posted on 2019-04-03

2867 Growth hormone induces TGF-β1 in podocytes: Implications in podocytopathy and proteinuria

Pasupulati, A. k.; Mukhi, D.; NISHAD, R.; Menon, R. K.

10.1101/597344 — cell biology — Posted on 2019-04-03

2868 Longitudinal Study of Leukocyte DNA Methylation and Biomarkers for Cancer Risk in Older Adults

Bartlett, A. H.; Liang, J. W.; Sandoval-Sierra, J. V.; Fowke, J. H.; Simonsick, E. M.; Johnson, K. C.; Mozhui, K.

10.1101/597666 — cancer biology — Posted on 2019-04-03

2869 Chromatin mapping and single-cell immune profiling define the temporal dynamics of ibrutinib drug response in chronic lymphocytic leukemia

Rendeiro, A. F.; Krausgruber, T.; Fortelny, N.; Zhao, F.; Penz, T.; Farlik, M.; Schuster, L. C.; Nemc, A.; Tasnady, S.; Reti, M.; Matrai, Z.; Alpar, D.; Bodor, C.; Schmidl, C.; Bock, C.

10.1101/597005 — cancer biology — Posted on 2019-04-03

2870 Phosphorimidate Derivatives of Acyclovir; Antiviral Activity Against Canine Parvovirus In Vitro

Mali, A.; Oak, P.; Chopade, A.; Shukla, G.

10.1101/598177 — pharmacology and toxicology — Posted on 2019-04-03

2871 Large-scale death of retinal astrocytes duringnormal development mediated by microglia

Punal, V. M.; Paisley, C. E.; Brecha, F. S.; Lee, M. A.; Perelli, R. M.; O'Koren, E. G.; Ackley, C. R.; Saban, D. R.; Reese, B. E.; Kay, J. N.

10.1101/593731 — neuroscience — Posted on 2019-04-03

2872 MicroRNAs expressed from FSHR and aromatase genes target important ovarian functions

Rooda, I.; Kaselt, B.; Salumets, A.; Velthut-Meikas, A.

10.1101/597054 — molecular biology — Posted on 2019-04-03

2873 Influenza Classification from Short Reads with VAPOR Facilitates Robust Mapping Pipelines and Zoonotic Strain Detection for Routine Surveillance Applications

Southgate, J. A.; Bull, M. J.; Brown, C. M.; Watkins, J.; Corden, S.; Southgate, B. D.; Moore, C.; Connor, T. R.

10.1101/597062 — bioinformatics — Posted on 2019-04-03

2874 Suppression of unwanted CRISPR/Cas9 editing by co-administration of catalytically inactivating truncated guide RNAs

Rose, J. C.; Popp, N. A.; Richardson, C. D.; Stephany, J. J.; Mathieu, J.; Wei, C. T.; Corn, J. E.; Maly, D. J.; Fowler, D. M.

10.1101/597849 — molecular biology — Posted on 2019-04-03

2875 Voltage-dependent activation of Rac1 by Nav1.5 channels promotes cell migration

Yang, M.; James, A. D.; Suman, R.; Kasprowicz, R.; Nelson, M.; O'Toole, P.; Brackenbury, W. J.

10.1101/597088 — cell biology — Posted on 2019-04-03

2876 Structure and Functional Binding Epitope of V-domain Ig Suppressor of T-cell Activation (VISTA)

Mehta, N.; Maddineni, S.; Mathews, I. I.; Sperberg, A. P.; Huang, P.-S.; Cochran, J. R.

10.1101/597716 — cancer biology — Posted on 2019-04-03

2877 Protein structure prediction using sparse NOE and RDC restraints with Rosetta in CASP13

Kuenze, G.; Meiler, J.

10.1101/597724 — biophysics — Posted on 2019-04-03

2878 Integrative protein modeling in RosettaNMR from sparse paramagnetic restraints

Kuenze, G.; Bonneau, R.; Koehler Leman, J.; Meiler, J.

10.1101/597872 — biophysics — Posted on 2019-04-03

2879 dSreg: A bayesian model to integrate changes in splicing and RNA binding protein activity

Marti-Gomez, C.; Lara-Pezzi, E.; Sanchez-Cabo, F.

10.1101/595751 — bioinformatics — Posted on 2019-04-03

2880 Charge-perturbation dynamics - a new avenue towards in silico protein folding

Pant, P.; Tristao Ramos, R. J.; Ionescu, C.-M.; Koca, J.

10.1101/597039 — bioinformatics — Posted on 2019-04-03

2881 Potential role of heat shock protein 90 in regulation of hyperthermia-driven differentiation of neural stem cells

Wang, L.; Zhuo, Y.; He, Z.; Lu, M.; Xia, Y.

10.1101/598441 — cell biology — Posted on 2019-04-03

2882 Motion prediction enables simulated MR-imaging of freely moving model organisms

Reischl, M.; Jouda, M.; MacKinnon, N.; Fuhrer, E.; Bakhtina, N.; Barschat, A.; Mikut, R.; Korvink, J. G.

10.1101/598524 — systems biology — Posted on 2019-04-03

2883 In silico bacteria evolve robust cooperation via complex quorum-sensing strategies

Wang, Y.; Rattray, J. B.; Thomas, S. A.; Gurney, J.; Brown, S. P.

10.1101/598508 — microbiology — Posted on 2019-04-03

2884 Applying particle filtering in complex compartmental models of pre-vaccination pertussis

Li, X.; Osgood, N.

10.1101/598490 — epidemiology — Posted on 2019-04-03

2885 Characterizing macroinvertebrate community composition and abundance in freshwater tidal wetlands of the Sacramento-San Joaquin Delta

Hartman, R.; Sherman, S.; Contreras, D.; Furler, A.; Kok, R.

10.1101/598482 — ecology — Posted on 2019-04-03

2886 Heat tolerance and acclimation capacity in unrelated subterranean arthropods living under common and stable thermal conditions

Pallares, S.; Colado, R.; Perez-Fernandez, T.; Wesener, T.; Ribera, I.; Sanchez-Fernandez, D.

10.1101/598458 — ecology — Posted on 2019-04-03

2887 Pluripotent Stem Cells Can Be Isolated from Human Peripheral Nerves after in vitro BMP-2 Stimulation

Sun, R.-Y.; Heggeness, M. H.; Jia, T.; Shrestha, S.; Dart, B.; Yang, S.-Y.

10.1101/598433 — cell biology — Posted on 2019-04-03

2888 Improvement in auditory spatial discrimination from ambiguous visual stimuli is not explained by ideal observer causal inference

Cappelloni, M. S.; Shivkumar, S.; Haefner, R. M.; Maddox, R. K.

10.1101/598425 — animal behavior and cognition — Posted on 2019-04-03

2889 Investigating risk factors that predict a dogs fear during veterinary visits

Edwards, P.; Hazel, S. J.; Browne, M.; Serpell, J.; McArthur, M. L.; Smith, B. P.

10.1101/598417 — animal behavior and cognition — Posted on 2019-04-03

2890 libsbmljs - Enabling Web--Based SBML Tools

Medley, K. K.; Hellerstein, J.; Sauro, H. M.

10.1101/594804 — systems biology — Posted on 2019-04-03

2891 Controllability Governs the Balance Between Pavlovian and Instrumental Action Selection

Dorfman, H. M.; Gershman, S. J.

10.1101/596577 — neuroscience — Posted on 2019-04-03

2892 Oligotyping and Genome-Resolved Metagenomics Reveal Distinct Candidatus Accumulibacter Communities in Full-Scale Side-Stream versus Conventional Enhanced Biological Phosphorus Removal (EBPR) Configurations

Srinivasan, V. N.; Li, G.; Wang, D.; Tooker, N. B.; Dai, Z.; Onnis-Hayden, A.; Pinto, A. J.; Gu, A. Z.

10.1101/596692 — microbiology — Posted on 2019-04-03

2893 Associated organisms inhabiting the calcareous sponge Clathrina lutea in La Parguera Natural Reserve, Puerto Rico

Garcia-Hernandez, J. E.; Hammerman, N. M.; Cruz-Motta, J. J.; Schizas, N. V.

10.1101/596429 — ecology — Posted on 2019-04-03

2894 dropClust2: An R package for resource efficient analysis of large scale single cell RNA-Seq data

Sinha, D.; Sinha, P.; Saha, R.; Bandyopadhyay, S.; Sengupta, D.

10.1101/596924 — bioinformatics — Posted on 2019-04-03

2895 Differential expression of glutamate transporters and monoaminergic genes in major depression and suicide.

Powers, B.; Kleinman, J. E.; Hyde, T. M.; Ajilore, O.; Leow, A.; Sodhi, M.

10.1101/596403 — pharmacology and toxicology — Posted on 2019-04-03

2896 Achronopresence: how temporal visuotactile and visuomotor mismatches modulate embodiment

Roel Lesur, M.; Weijs, M. L.; Simon, C.; Kannape, O. A.; Lenggenhager, B.

10.1101/596858 — neuroscience — Posted on 2019-04-03

2897 Rapid and label-free identification of individual bacterial pathogens exploiting three-dimensional quantitative phase imaging and deep learning

Kim, G.; Ahn, D.; Kang, M.; Jo, Y.; Ryu, D.; Kim, H.; Song, J.; Ryu, J. S.; Choi, G.; Chung, H. J.; Kim, K.; Chung, D. R.; Yoo, I. Y.; Huh, H. J.; Min, H.; Lee, N. Y.; Park, Y.

10.1101/596486 — microbiology — Posted on 2019-04-03

2898 Uncovering complex disease subtypes by integrating clinical data and imputed transcriptome from genome-wide association studies: Applications in psychiatry and cardiovascular medicine

Yin, L.; Chau, C. K. L.; Sham, P.-C.; So, H.-C.

10.1101/595488 — genetics — Posted on 2019-04-03

2899 IKAP - Identifying K mAjor cell Population groups in single-cell RNA-seq analysis

Chen, Y.-C.; Suresh, A.; Underbayev, C.; Sun, C.; Singh, K.; Seifuddin, F.; Wiestner, A.; Pirooznia, M.

10.1101/596817 — bioinformatics — Posted on 2019-04-03

2900 OPENANNO: annotating genomic regions with chromatin accessibility

Chen, S.; Wang, Y.; Jiang, R.

10.1101/596627 — bioinformatics — Posted on 2019-04-03

2901 RNA base pairing complexity in living cells visualized by correlated chemical probing

Mustoe, A. M.; Lama, N.; Irving, P. S.; Olson, S. W.; Weeks, K. M.

10.1101/596353 — biochemistry — Posted on 2019-04-03

2902 Firing rate distributions in spiking networks with heterogeneous connectivity

Vegue, M.; Roxin, A.

10.1101/542456 — neuroscience — Posted on 2019-04-02

2903 Structural variants, hemizygosity and clonal propagation in grapevines (Vitis vinifera)

Zhou, Y. S.; Minio, A.; Massonnet, M.; Solares, E. A.; Lyu, Y.; Beridze, T.; Cantu, D.; Gaut, B. S.

10.1101/508119 — evolutionary biology — Posted on 2019-04-02

2904 Phosphodiesterase 5 inhibition improves contractile function and restores transverse tubule loss and catecholamine responsiveness in heart failure.

Lawless, M.; Caldwell, J. L.; Radcliffe, E. J.; Smith, C. E. R.; Madders, G. W.; Huthchings, D. C.; Woods, L. S.; Church, S. J.; Unwin, R. D.; Kirkwood, G. J.; Becker, L. K.; Pearman, C. M.; Taylor, R. F.; Eisner, D. A.; Dibb, K. M.; Trafford, A. W.

10.1101/248187 — physiology — Posted on 2019-04-02

2905 A combination of running and memantine increases neurogenesis and reduces activation of developmentally-born dentate granule neurons in rats

Cahill, S. P.; Martinovic, A.; Cole, J. D.; Snyder, J. S.

10.1101/545673 — neuroscience — Posted on 2019-04-02

2906 Molecular determinants of metazoan tricRNA biogenesis

Schmidt, C. A.; Giusto, J. D.; Bao, A.; Hopper, A. K.; Matera, A. G.

10.1101/497545 — molecular biology — Posted on 2019-04-02

2907 Tracking the popularity and outcomes of all bioRxiv preprints

Abdill, R. J.; Blekhman, R.

10.1101/515643 — scientific communication and education — Posted on 2019-04-02

2908 A statistical simulator scDesign for rational scRNA-seq experimental design

Li, W. V.; Li, J. J.

10.1101/437095 — bioinformatics — Posted on 2019-04-02

2909 Early Hippocampal Sharp-Wave Ripple Deficits Predict Later Learning and Memory Impairments in an Alzheimer’s Disease Mouse Model

Jones, E. A.; Gillespie, A. K.; Yoon, S. Y.; Frank, L. M.; Huang, Y.

10.1101/596569 — neuroscience — Posted on 2019-04-02

2910 The brain detects stimulus features, but not stimulus conflict in task-irrelevant sensory input

Nuiten, S. A.; Canales-Johnson, A.; Beerendonk, L.; Nanuashvili, N.; Fahrenfort, J.; Bekinschtein, T.; van Gaal, S.

10.1101/596999 — neuroscience — Posted on 2019-04-02

2911 Patterns of urine scent mark pheromone evolution in house mice and relatives (Muridae: Mus)

Sheehan, M.; Campbell, P.; Miller, C. H.

10.1101/597203 — evolutionary biology — Posted on 2019-04-02

2912 γBOriS: Identification of Origins of Replication in Gammaproteobacteria using Motif-based Machine Learning

Sperlea, T.; Muth, L.; Martin, R.; Weigel, C.; Waldminghaus, T.; Heider, D.

10.1101/597070 — bioinformatics — Posted on 2019-04-02

2913 What, if anything, is the true neurophysiological significance of rotational dynamics?

Lebedev, M. A.; Adell Mill, N.; Armengol Urpi, N.; Cervera, M. R.; Nicolelis, M. A.

10.1101/597419 — neuroscience — Posted on 2019-04-02

2914 Classification of Neurons in the Adult Mouse Cochlear Nucleus: Linear Discriminant Analysis

Manis, P. B.; Kasten, M. R.; Xie, R.

10.1101/594713 — neuroscience — Posted on 2019-04-02

2915 Latitudinal MHC variation and haplotype associated differential survival in response to experimental infection of two strains of Batrachochytrium dendrobatitis (Bd-GPL) in common toads

cortazar, M.; Meurling, S.; schroyens, L.; Siljestam, M.; Ritcher-Boix, A.; Laurila, A.; Hoglund, J.

10.1101/597559 — evolutionary biology — Posted on 2019-04-02

2916 Regulation of subcellular dendritic synapse specificity by axon guidance cues

Sales, E. C.; Heckman, E. L.; Warren, T.; Doe, C. Q.

10.1101/597351 — neuroscience — Posted on 2019-04-02

2917 Territory acquisition mediates the influence of predators and climate on juvenile red squirrel survival

Hendrix, J. G.; Fisher, D. N.; Martinig, A. R. M.; Boutin, S.; Dantzer, B.; Lane, J. E.; McAdam, A. G.

10.1101/594036 — ecology — Posted on 2019-04-02

2918 Autochthonous faecal virome transplantation (FVT) reshapes the murine microbiome after antibiotic perturbation

Draper, L. A.; Ryan, F. J.; Dalmasso, M.; Casey, P. G.; McCann, A.; Velayudhan, V.; Ross, R. P.; Hill, C.

10.1101/591099 — microbiology — Posted on 2019-04-02

2919 Loss-of-function genomic variants with impact on liver-related blood traits highlight potential therapeutic targets for cardiovascular disease

Nielsen, J. B.; Rom, O.; Surakka, I.; Graham, S. E.; Zhou, W.; Fritsche, L. G.; Gagliano Taliun, S. A.; Sidore, C.; Liu, Y.; Gabrielsen, M. E.; Skogholt, A. H.; Wolford, B.; Overton, W.; Hornsby, W. E.; Acheampong, A.; Grooms, A.; Roychowdhury, T.; Schaefer, A.; Zajac, G. J.; Villacorta, L.; Zhang, J.; Brumpton, B.; Loset, M.; Rai, V.; Taylor, K. D.; Palmer, N. D.; Chen, Y.-D.; Choi, S. H.; Lubitz, S. A.; Ellinor, P. T.; Barnes, K. C.; Daya, M.; Rafaels, N.; Weiss, S. T.; Lasky-Su, J.; Tracy, R. P.; Vasan, R. S.; Cupples, L. A.; Mathias, R. A.; Yanek, L. R.; Becker, L. C.; Peyser, P. A.; Biela

10.1101/597377 — genomics — Posted on 2019-04-02

2920 Allododecaploid yeasts: synthetic hybrids of six species

Peris, D.; Moriarty, R. V.; Alexander, W. G.; Wrobel, R. L.; Hittinger, C. T.

10.1101/597633 — genetics — Posted on 2019-04-02

2921 Multi-omic regulatory networks capture downstream effects of kinase inhibition in Mycobacterium tuberculosis

Young, A. T.; Carette, X.; Helmel, M.; Steen, H.; Husson, R. N.; Quackenbush, J.; Platig, J.

10.1101/584177 — systems biology — Posted on 2019-04-02

2922 Dental caries in human evolution: frequency of carious lesions in South African fossil hominins

Towle, I.; Irish, J. D.; De Groote, I.; Fernee, C.

10.1101/597385 — paleontology — Posted on 2019-04-02

2923 Task context modulates feature-selective responses in area V4

Popovkina, D. V.; Pasupathy, A.

10.1101/594150 — neuroscience — Posted on 2019-04-02

2924 Establishing insect community composition using metabarcoding of soil samples, and preservative ethanol and homogenate from Malaise trap catches: surprising inconsistencies between methods.

Marquina, D.; Esparza-Salas, R.; Roslin, T.; Ronquist, F.

10.1101/597302 — ecology — Posted on 2019-04-02

2925 Performance of bitumen coating sheet using biomass pyrolysis oil

Ren, Y.; Zhang, L.; Duan, W.; Han, Z.; Guo, J.; Heydenrych, M. D.; Zhang, A.; Nie, K.; Tan, T.; Liu, L.

10.1101/592246 — bioengineering — Posted on 2019-04-02

2926 Epsilon-Genic Effects Bridge the Gap Between Polygenic and Omnigenic Complex Traits

Cheng, W.; Ramachandran, S.; Crawford, L.

10.1101/597484 — genetics — Posted on 2019-04-02

2927 Temporal gating of SIRT1 functions by O-GlcNAcylation prevents hyperglycemia and enables physiological transitions in liver

Chattopadhyay, T.; Maniyadath, B.; Bagul, H. P.; Chakraborty, A.; Shukla, N.; Budnar, S.; Kolthur-Seetharam, U.

10.1101/597153 — physiology — Posted on 2019-04-02

2928 The human-specific paralogs SRGAP2B and SRGAP2C differentially modulate SRGAP2A-dependent synaptic development

Schmidt, E. R.; Kupferman, J.; Stackmann, M.; Polleux, F.

10.1101/596940 — neuroscience — Posted on 2019-04-02

2929 Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance

Pech, M. F.; Villalta, J. E.; Chan, L. J. G.; Kharbanda, S.; O'Brien, J. J.; McAllister, F. E.; Firestone, A. J.; Jan, C. H.; Settleman, J.

10.1101/597567 — cancer biology — Posted on 2019-04-02

2930 Translational control of breast cancer plasticity

Jewer, M.; Lee, L.; Zhang, G.; Liu, J.; Findlay, S. D.; Vincent, K. M.; Tandoc, K.; Dieters-Castator, D.; Quail, D. F.; Dutta, I.; Coatham, M.; Xu, Z.; Guan, B.-J.; Hatzoglou, M.; Brumwell, A.; Uniacke, J.; Patsis, C.; Koromilas, A.; Schueler, J.; Siegers, G. M.; Topisirovic, I.; Postovit, L.-M.

10.1101/596544 — cancer biology — Posted on 2019-04-02

2931 Targeting IL-6 reduces IgM levels and tumor growth in Waldenstrom macroglobulinemia

Han, W.; Matissek, S. J.; Jackson, D. A.; Sklavanitis, B.; Elsawa, S. F.

10.1101/592642 — cancer biology — Posted on 2019-04-02

2932 A role for Hypoxia Inducible Factor 1a (HIF1a) in intermittent hypoxia-dependent changes in spatial memory and synaptic plasticity

Arias-Cavieres, A.; Khuu, M. A.; Nwakudu, C. U.; Barnard, J. E.; Dalgin, G.; Garcia, A. J.

10.1101/595975 — neuroscience — Posted on 2019-04-02

2933 Spherical Spindle Shape Promotes Perpendicular Cortical Orientation by Preventing Isometric Cortical Pulling on both Spindle Poles during C. elegans Female Meiosis

Vargas, E.; McNally, K.; Cortes, D.; Panzica, M.; Shaub-Maddox, A.; McNally, F.

10.1101/596510 — cell biology — Posted on 2019-04-02

2934 Different localization of fluorescently labeled N- and C-termini of nucleolin variants in human glioblastoma cell culture

Panteleev, D.; Pustogarov, N.; Revishchin, A.; Shamadykova, D.; Drozd, S.; Goryanov, S.; Potapov, A.; Pavlova, G.

10.1101/596916 — cancer biology — Posted on 2019-04-02

2935 Nanoaperture fabrication via colloidal lithography for single molecule fluorescence imaging

Jamiolkowski, R. M.; Chen, K. Y.; Fiorenza, S. A.; Tate, A. M.; Pfeil, S. H.; Goldman, Y. E.

10.1101/596460 — biophysics — Posted on 2019-04-02

2936 Tubulin Lattice in Cilia is in a Stressed Form Regulated by Microtubule Inner Proteins

Ichikawa, M.; Khalifa, A. A.; Basu, K.; Dai, D.; Faghfor Maghrebi, M. A.; Vargas, J.; Bui, K. H.

10.1101/596478 — biophysics — Posted on 2019-04-02

2937 The lipid phosphatase-like protein PLPPR1 increases cell adhesion by modulating RhoA/Rac1 activity

Agbaegbu Iweka, C.; Tilve, S.; Mencio, C. P.; Katagiri, Y.; Geller, H. M.

10.1101/470914 — neuroscience — Posted on 2019-04-02

2938 Paternally-acting canonical RNA-directed DNA methylation pathway genes sensitize Arabidopsis endosperm to paternal genome dosage

Satyaki, P. R. V.; Gehring, M.

10.1101/527853 — plant biology — Posted on 2019-04-02

2939 CBP/EP300-dependent acetylation and stabilization of HSF2 are compromised in Rubinstein-Taybi syndrome

10.1101/481457 — developmental biology — Posted on 2019-04-02

2940 Seasonal patterns of dengue fever in rural Ecuador: 2009-2016

Sippy, R. J.; Gaus, D.; Herrera, D.; Gangnon, R.; Patz, J.; Osorio, J.

10.1101/452318 — epidemiology — Posted on 2019-04-02

2941 Non-Parametric Analysis of Thermal Proteome Profiles Reveals Novel Drug-Binding Proteins

Childs, D.; Bach, K.; Franken, H.; Anders, S.; Kurzawa, N.; Bantscheff, M.; Savitski, M.; Huber, W.

10.1101/373845 — bioinformatics — Posted on 2019-04-02

2942 Directed networks as a novel way to describe and analyze cardiac excitation: Directed Graph mapping

Vandersickel, N.; Van Nieuwenhuyse, E.; Van Cleemput, N.; Goedgebeur, J.; El Haddad, M.; De Neve, J.; Strisciuglio, T.; Duytschaever, M.; Panfilov, A.

10.1101/596288 — physiology — Posted on 2019-04-02

2943 Alterations in Dynamic Spontaneous Network Microstates in Mild Traumatic Brain Injury: A MEG Beamformed Dynamic Connectivity Analysis

Antonakakis, M.; Dimitriadis, S. I.; Zervakis, M.; Papanicolaou, A. C.; Zouridakis, G.

10.1101/596155 — neuroscience — Posted on 2019-04-02

2944 Forward genetic screen for Caenorhabditis elegans mutants with a shortened locomotor healthspan

Kawamura, K.; Maruyama, I. N.

10.1101/487876 — genetics — Posted on 2019-04-02

2945 Understanding patterns of abiotic and biotic stress resilience to unleash the potential of crop wild relatives for climate-smart legume breeding

van Zonneveld, M.; Rakha, M.; Tan, S.-y.; Chou, Y.-y.; Chang, C.-h.; Yen, J.; Schafleitner, R.; Nair, R.; Naito, K.; Solberg, S. O.

10.1101/596072 — plant biology — Posted on 2019-04-02

2946 Fronto-striatal Functional Connectivity Supports Reward-Enhanced Memory in Older Adults

Bowen, H. J.; Ford, J. H.; Grady, C. L.; Spaniol, J.

10.1101/592501 — neuroscience — Posted on 2019-04-02

2947 Interactions between the gut microbiome and host gene regulation in cystic fibrosis

Dayama, G.; Priya, S.; Niccum, D. E.; Khoruts, A.; Blekhman, R.

10.1101/596312 — genomics — Posted on 2019-04-02

2948 Weighted burden analysis of exome-sequenced late onset Alzheimer’s cases and controls provides further evidence for involvement of PSEN1 and demonstrates protective role for variants in tyrosine phosphatase genes

Curtis, D.

10.1101/596007 — genetics — Posted on 2019-04-02

2949 The thin edge of the wedge: extremely high extinction risk in wedgefishes and giant guitarfishes

Kyne, P. M.; Jabado, R. W.; Rigby, C. L.; Dharmadi, ; Gore, M. A.; Pollock, C. M.; Herman, K. B.; Cheok, J.; Ebert, D. A.; Simpfendorfer, C. A.; Dulvy, N. K.

10.1101/595462 — ecology — Posted on 2019-04-02

2950 The biochemical activities of the Saccharomyces cerevisiae Pif1 helicase are regulated by its N-terminal domain

Nickens, D. G.; Sausen, C. W.; Bochman, M.

10.1101/596098 — biochemistry — Posted on 2019-04-02

2951 Dynamics of inhibitory control during bilingual speech production: An electrophysiological study

Zheng, X.; Roelofs, A.; Erkan, H.; Lemhofer, K.

10.1101/596445 — neuroscience — Posted on 2019-04-02

2952 Disambiguating the role of blood flow and global signal with Partial Information Decomposition

Colenbier, N.; Van de Steen, F.; Uddin, L.; Poldrack, R.; Calhoun, V.; Marinazzo, D.

10.1101/596247 — neuroscience — Posted on 2019-04-02

2953 Horizontal gene transfer by natural transformation promotes both genetic and epigenetic inheritance of traits

Dalia, A. B.; Dalia, T. N.

10.1101/596379 — microbiology — Posted on 2019-04-02

2954 Copy number variant syndromes are frequent in schizophrenia: progressing towards a CNV-schizophrenia model

Sriretnakumar, V.; Zai, C. C.; Wasim, S.; Barsanti-Innes, B.; Kennedy, J. L.; So, J.

10.1101/596213 — genetics — Posted on 2019-04-02

2955 Landowner Functional Types to Characterize Response to Forest Insects

Holt, J. R.; Borsuk, M. E.; Butler, B. J.; Kittredge, D. B.; Laflower, D.; MacLean, M. G.; Markowski-Lindsay, M.; Orwig, D.; Thompson, J. R.

10.1101/596189 — ecology — Posted on 2019-04-02

2956 Accelerated Cortical Thinning within Structural Brain Networks is Associated with Irritability in Youth

Jirsaraie, R. J.; Kaczkurkin, A. N.; Rush, S.; Piiwia, K.; Adebimpe, A.; Bassett, D. S.; Bourque, J.; Calkins, M. E.; Cieslak, M.; Ciric, R.; Cook, P. A.; Davila, D.; Elliott, M. A.; Leibenluft, E.; Murtha, K.; Roalf, D. R.; Rosen, A. F. G.; Ruparel, K.; Shinohara, R. T.; Sotiras, A.; Wolf, D. H.; Davatzikos, C.; Satterthwaite, T. D.

10.1101/596346 — neuroscience — Posted on 2019-04-02

2957 The anatomical boundary of the rat claustrum

Dillingham, C. M.; Mathiasen, M. L.; Frost, B. E.; Lambert, M. A.; Bubb, E. J.; Jankowski, M. M.; Aggleton, J. P.; O'Mara, S. M.

10.1101/596304 — neuroscience — Posted on 2019-04-02

2958 SymSim: simulating multi-faceted variability in single cell RNA sequencing

Zhang, X.; Xu, C.; Yosef, N.

10.1101/378646 — bioinformatics — Posted on 2019-04-02

2959 Neurogranin Stimulates Ca2+/calmodulin-dependent Kinase II by Inhibiting Calcineurin at Specific Calcium Spike Frequencies

Li, L.; Lai, M.; Cole, S.; Le Novere, N.; Edelstein, S. J.

10.1101/597278 — neuroscience — Posted on 2019-04-02

2960 CGGBP1 regulates chromatin barrier activity and CTCF occupancy at repeats

Patel, D. K.; Patel, M.; Singh, U.

10.1101/593137 — genomics — Posted on 2019-04-02

2961 Understanding the molecular mechanism of umami recognition by T1R1-T1R3 using molecular dynamics simulations

Liu, H.; Da, L.-T.; Liu, Y.

10.1101/597286 — molecular biology — Posted on 2019-04-02

2962 Prevalence and socioeconomic determinants of development delay among children in Ceara, Brazil: a population-based study

Correia, L. L.; Rocha, H. A. L.; Sudfeld, C. R.; Rocha, S. G. M. O.; Leite, A. J. M.; Campos, J. S.; Silva, A. C. e.

10.1101/597252 — epidemiology — Posted on 2019-04-02

2963 Predicting gait adaptations due to ankle plantarflexor muscle weakness and contracture using physics-based musculoskeletal simulations

Ong, C. F.; Geijtenbeek, T.; Hicks, J. L.; Delp, S. L.

10.1101/597294 — bioengineering — Posted on 2019-04-02

2964 Insights from Fisher’s geometric model on the likelihood of speciation under different histories of environmental change

Yamaguchi, R.; Otto, S. P.

10.1101/596866 — evolutionary biology — Posted on 2019-04-02

2965 Growth Patterns of birds, dinosaurs and reptiles: Are differences real or apparent?

Kühleitner, M.; Brunner, N.; Nowak, W. G.; Renner-Martin, K.; Scheicher, K.

10.1101/597260 — scientific communication and education — Posted on 2019-04-02

2966 Combined effects of age and BMI are related to altered cortical thickness in adolescence and adulthood

Westwater, M. L.; Vilar-Lopez, R.; Ziauddeen, H.; Verdejo-Garcia, A.; Fletcher, P. C.

10.1101/596064 — neuroscience — Posted on 2019-04-02

2967 Quantification of microaerobic growth of Geobacter sulfurreducens

Engel, C. E. A.; Vorländer, D.; Biedendieck, R.; Krull, R.; Dohnt, K.

10.1101/597229 — microbiology — Posted on 2019-04-02

2968 Prevalence and determinants of neonatal danger signs in northwest Ethiopia: a multilevel analysis

Bogale, T. N.; Worku, A.; Worku, A.; Bikis, G.; Kebede, Z.

10.1101/597245 — epidemiology — Posted on 2019-04-02

2969 Managing congestion at visitor hotspots using park-level use level data: Case study of a Chinese World Heritage site

Guo, J.-H.; Guo, T.; Lin, K.-M.; Leung, Y.-F.; Chen, Q.-H.

10.1101/596031 — ecology — Posted on 2019-04-02

2970 Muscle fiber hypertrophy in response to 6 weeks of high-volume resistance training in trained young men is largely attributed to sarcoplasmic hypertrophy

Haun, C.; Vann, C.; Osburn, S.; Mumford, P.; Roberson, P.; Romero, M.; Fox, C.; Johnson, C.; Parry, H.; Kavazis, A.; Moon, J.; Badsia, V.; Mwashote, B.; Ibeanusi, V.; Young, K.; Roberts, M.

10.1101/596049 — molecular biology — Posted on 2019-04-02

2971 Primary pterygium was not associated with corneal endothelial cell decrease in a rural Chinese population

Hu, Y.; Li, L.; Qi, W.; Liu, Z.; Liu, Y.; Yuan, L.

10.1101/595892 — epidemiology — Posted on 2019-04-02

2972 Medroxyprogesterone reverses tolerable dose metformin-induced inhibition of invasion via matrix metallopeptidase-9 and transforming growth factor-β1 in KLE endometrial cancer cells

Suh, D. H.; Lee, S.; Park, H.-S.; Park, N. H.

10.1101/596056 — cancer biology — Posted on 2019-04-02

2973 A biochemical mechanism for time-encoding memory formation within individual synapses of Purkinje cells

Mandwal, A.; Orlandi, J.; Simon, C.; Davidsen, J.

10.1101/596148 — neuroscience — Posted on 2019-04-02

2974 TLR-induced reorganization of the IgM-BCR complex regulates B-1 cell responses to infections

Savage, H. P.; Kläsener, K.; Smith, F. L.; Reth, M.; Baumgarth, N.

10.1101/595694 — immunology — Posted on 2019-04-02

2975 Cryptic asexual reproduction in Caenorhabditis nematodes revealed by interspecies hybridization

Lamelza, P.; Young, J. M.; Noble, L. M.; Isakharov, A.; Palanisamy, M.; Rockman, M. V.; Malik, H. S.; Ailion, M.

10.1101/588152 — evolutionary biology — Posted on 2019-04-02

2976 Nasal and gut microbiota for sows of different health status within six commercial swine farms from one swine production system

Arruda, A. G.; Deblais, L.; Hale, V.; Pairis-Garcia, M.; Srivastava, V.; Kathayat, D.; Kumar, A.; Rajashekara, G.

10.1101/596130 — epidemiology — Posted on 2019-04-02

2977 VEGF and FGF signaling during head regeneration in hydra

Turwankar, A.; Ghaskadbi, S.

10.1101/596734 — cell biology — Posted on 2019-04-02

2978 Cardiorespiratory fitness predicts greater hippocampal volume and rate of episodic associative learning in older adults

Cole, R. C.; Hazeltine, E.; Weng, T. B.; Wharff, C.; DuBose, L. E.; Schmid, P.; Sigurdsson, G.; Magnotta, V. A.; Pierce, G. L.; Voss, M. W.

10.1101/578237 — neuroscience — Posted on 2019-04-02

2979 Tissue and cell-type specific expression of a splice variant in the II-III cytoplasmic loop of Cacna1b

Bunda, A.; LaCarubba, B.; Akiki, M.; Andrade, A.

10.1101/596668 — neuroscience — Posted on 2019-04-02

2980 Temporary anosmia in mice following nasal lavage with dilute detergent solution

Mast, T. G.; Zuk, K.; Rinke, A.; Quasem, K.; Savard, B.; Brobbey, C.; Reiss, J.; Dryden, M.

10.1101/596601 — neuroscience — Posted on 2019-04-02

2981 Suppression of transcytosis regulates zebrafish blood-brain barrier development

O'Brown, N. M.; Megason, S. G.; Gu, C.

10.1101/596221 — developmental biology — Posted on 2019-04-02

2982 Real-time integration of cell death and proliferation kinetics at the single-cell and population-level using high-throughput live-cell imaging.

Gelles, J. D.; Mohammed, J. N.; Santos, L. C.; Chipuk, J. E.

10.1101/596239 — cell biology — Posted on 2019-04-02

2983 Modeling the demography of species providing extended parental care: A capture-recapture approach with a case study on Polar Bears (Ursus maritimus)

Cubaynes, S.; Aars, J.; Yoccoz, N.; Pradel, R.; Wiig, O.; Ims, R.; Gimenez, O.

10.1101/596437 — ecology — Posted on 2019-04-02

2984 Conserved architecture of Tc toxins from human and insect pathogenic bacteria

Leidreiter, F.; Roderer, D.; Meusch, D.; Gatsogiannis, C.; Benz, R.; Raunser, S.

10.1101/596536 — molecular biology — Posted on 2019-04-02

2985 A heterochromatin-specific RNA export pathway facilitates piRNA production

ElMaghraby, M. F.; Andersen, P. R.; Puehringer, F.; Meixner, K.; Lendl, T.; Tirian, L.; Brennecke, J.

10.1101/596171 — molecular biology — Posted on 2019-04-02

2986 Physical and data structure of 3D genome

Huang, K.; Li, Y.; Shim, A. R.; Nap, R. J.; Agrawal, V.; Virk, R. K. A.; Eshein, A.; Almassalha, L. M.; Backman, V.; Szleifer, I.

10.1101/596262 — biophysics — Posted on 2019-04-02

2987 Molecular Dynamics Analysis of Mg2+-dependent Cleavage of a Pistol Ribozyme Reveals a Fail-safe Secondary Ion for Catalysis

Roy, R. N.; Joseph, N. N.; Steitz, T. A.

10.1101/596270 — biophysics — Posted on 2019-04-02

2988 Single subunit degradation of WIZ, a lenalidomide- and pomalidomide dependent substrate of E3 ubiquitin ligase CRL4CRBN

Yu, H. H.; Reitsma, J. M.; Sweredoski, M. J.; Moradian, A.; Hess, S.; Deshaies, R. J.

10.1101/595389 — biochemistry — Posted on 2019-04-02

2989 Is mechanical receptor ligand dissociation driven by unfolding or unbinding?

Milles, L.; Gaub, H. E.

10.1101/593335 — biophysics — Posted on 2019-04-02

2990 Warming can destabilise predator-prey interactions by shifting the functional response from Type III to Type II

Daugaard, U.; Petchey, O.; Pennekamp, F.

10.1101/498030 — ecology — Posted on 2019-04-02

2991 LipoGlo: A sensitive and specific reporter of atherogenic lipoproteins

Thierer, J. H.; Ekker, S. C.; Farber, S. A.

10.1101/522615 — genetics — Posted on 2019-04-02

2992 Community size affects the signals of ecological drift and selection on biodiversity

Siqueira, T.; Saito, V. S.; Bini, L. M.; Melo, A. S.; Petsch, D. K.; Landeiro, V. L.; Tolonen, K. T.; Jyrkankallio-Mikkola, J.; Soininen, J.; Heino, J.

10.1101/515098 — ecology — Posted on 2019-04-02

2993 A new test of value-modulated attentional bias in mice

Hornoiu, I.; Gigg, J.; Talmi, D.

10.1101/495945 — neuroscience — Posted on 2019-04-02

2994 Aerodigestive sampling reveals altered microbial exchange between lung, oropharyngeal, and gastric microbiomes in children with impaired swallow function

Duvallet, C.; Larson, K.; Snapper, S.; Iosim, S.; Lee, A.; Freer, K.; May, K.; Alm, E.; Rosen, R.

10.1101/476580 — microbiology — Posted on 2019-04-02

2995 GA-repeats on mammalian X chromosomes support Ohno’s hypothesis of dosage compensation by transcriptional upregulation

D'Souza, E.; Weinand, K.; Hosage, E.; Gisselbrecht, S.; Markstein, V.; Markstein, P.; Bulyk, M.; Markstein, M.

10.1101/485300 — genomics — Posted on 2019-04-02

2996 Genealogical distances under low levels of selection

Huss, E.; Pfaffelhuber, P.

10.1101/495770 — evolutionary biology — Posted on 2019-04-02

2997 Identification of biomarkers and pathways to identify novel therapeutic targets in Alzheimers disease: Insights from a systems biomedicine perspective

Rahman, M. R.; Islam, T.; Zaman, T.; Shahjaman, M.; Karim, M. R.; Quinn, J. M. W.; Holsinger, R. M. D.; Moni, M. A.

10.1101/481879 — systems biology — Posted on 2019-04-02

2998 Serum triglycerides in Alzheimer’s disease: Relation to neuroimaging and CSF biomarkers

10.1101/441394 — neuroscience — Posted on 2019-04-02

2999 The Brain-Derived Neurotrophic Factor Val66Met Genotype Does Not Influence the Grey or White Matter Structures Underlying Recognition Memory

McKay, N. S.; Moreau, D.; Henare, D. T.; Kirk, I. J.

10.1101/461731 — neuroscience — Posted on 2019-04-02

3000 The Oligomerization Landscape of Histones

Zhao, H.; Winogradoff, D.; Dalal, Y.; Papoian, G.

10.1101/422360 — biophysics — Posted on 2019-04-02

3001 AIDE: annotation-assisted isoform discovery and abundance estimation with high precision

Li, W. V.; Li, S.; Tong, X.; Deng, L.; Shi, H.; Li, J. J.

10.1101/437350 — bioinformatics — Posted on 2019-04-02

3002 Prenatal exposure to particulate matter (PM2.5) and low birth weight in a Sri Lankan birth cohort

Tipre, M.; Wickremesinghe, R.; Nandasena, S.; Kasturiratne, A.; Larson, R.; Meleth, S.; Wimalasiri, U.; Smith, T.; Lungu, C.; Sathiakumar, N.

10.1101/461632 — epidemiology — Posted on 2019-04-02

3003 TrkB Activation During a Critical Period Mimics the Protective Effects of Early Visual Experience on Perception and the Stability of Receptive Fields in Adult Superior Colliculus

Mudd, D. B.; Balmer, T. S.; Kim, S. Y.; Machhour, N.; Pallas, S. L.

10.1101/435784 — neuroscience — Posted on 2019-04-02

3004 Candida albicans white and opaque cells exhibit distinct spectra of organ colonization in standard mouse models of infection

Takagi, J.; Singh-Babak, S. D.; Lohse, M. B.; Dalal, C. K.; Johnson, A. D.

10.1101/461293 — microbiology — Posted on 2019-04-02

3005 Cluster Burst Synchronization in A Scale-Free Network of Inhibitory Bursting Neurons

Kim, S.-Y.; Lim, W.

10.1101/414847 — neuroscience — Posted on 2019-04-02

3006 SymSim: simulating multi-faceted variability in single cell RNA sequencing

Zhang, X.; Xu, C.; Yosef, N.

10.1101/378646 — bioinformatics — Posted on 2019-04-02

3007 Inferring and validating mechanistic models of neural microcircuits based on spike-train data

Ladenbauer, J.; McKenzie, S.; English, D. F.; Hagens, O.; Ostojic, S.

10.1101/261016 — neuroscience — Posted on 2019-04-02

3008 Bed nucleus of the stria terminalis regulates fear to unpredictable threat signals

Goode, T. D.; Ressler, R. L.; Acca, G. M.; Miles, O.; Maren, S.

10.1101/376228 — neuroscience — Posted on 2019-04-02

3009 Volumetric and microstructural regional changes of the hippocampus underlying development of extended delay long-term memory

Fjell, A.; Sneve, M. H.; Sederevicius, D.; Sorensen, O.; Krogsrud, S.; Mowinckel, A.; Walhovd, K.

10.1101/595827 — neuroscience — Posted on 2019-04-01

3010 Optimal policy for multi-alternative decisions

Tajima, S.; Drugowitsch, J.; Patel, N.; Pouget, A.

10.1101/595843 — neuroscience — Posted on 2019-04-01

3011 Post-translational polymodification of the C-terminal tail of TUBB1 regulates motor protein processivity in platelet production and function

Khan, A. O.; Slater, A.; Maclachlan, A.; Nicolson, P. L.; Pike, J. A.; Yule, J.; Thomas, S. G.; Morgan, N. V.

10.1101/595868 — cell biology — Posted on 2019-04-01

3012 An oligomeric state-dependent switch in FICD regulates AMPylation and deAMPylation of the chaperone BiP

Perera, L. A.; Rato, C.; Yan, Y.; Neidhardt, L.; McLaughlin, S. H.; Read, R. J.; Preissler, S.; Ron, D.

10.1101/595835 — biochemistry — Posted on 2019-04-01

3013 Characterization of LINE-1 transposons in a human genome at allelic resolution

Yang, L.; Metzger, G. A.; McLaughlin, R. N.

10.1101/594200 — genomics — Posted on 2019-04-01

3014 Genome-Wide Fetalization of Enhancer Architecture in Heart Disease

Spurrell, C. H.; Barozzi, I.; Mannion, B. J.; Blow, M. J.; Fukuda-Yuzawa, Y.; Afzal, S. Y.; Akiyama, J. A.; Afzal, V.; Tran, S.; Plajzer-Frick, I.; Novak, C. S.; Kato, M.; Lee, E.; Garvin, T. H.; Pham, Q. T.; Harrington, A. N.; Lisgo, S.; Bristow, J.; Cappola, T. P.; Morley, M. P.; Margulies, K. B.; Pennacchio, L. A.; Dickel, D. E.; Visel, A.

10.1101/591362 — genomics — Posted on 2019-04-01

3015 LightDock goes information-driven

Roel Touris, J. L.; Bonvin, A. M. J. J.; Jimenez-Garcia, B.

10.1101/595983 — bioinformatics — Posted on 2019-04-01

3016 A DNA barcode reference library of the French Polynesian shore fishes

DELRIEU-TROTTIN, E.; Williams, J. T.; Pitassy, D.; Driskell, A.; Hubert, N.; Viviani, J.; Cribb, T. H.; Espiau, B.; Galzin, R.; Kulbicki, M.; Lison de Loma, T.; Meyer, C.; Mourier, J.; Mou-Tham, G.; Parravicini, V.; Plantard, P.; Sasal, P.; Siu, G.; Tolou, N.; Veuille, M.; Weigt, L.; Planes, S.

10.1101/595793 — zoology — Posted on 2019-04-01

3017 Optimization of a Modular Steroid-Inducible Gene Expression System for Use in Rice

Vlad, D.; Samalova, M.; Abu Jamous, B.; Wang, P.; Moore, I. R.; Langdale, J. A.

10.1101/595579 — plant biology — Posted on 2019-04-01

3018 Methylomic profiles reveal sex-specific shifts in leukocyte composition associated with post-traumatic stress disorder

Kim, G. S.; Smith, A.; Xu, F.; Michopoulos, V.; Lori, A.; Armstrong, D. L.; Aiello, A. E.; Koenen, K. C.; Galea, S.; Wildman, D. E.; Uddin, M.

10.1101/594127 — genomics — Posted on 2019-04-01

3019 Dental abscesses on the maxilla of a two million-year-old early Homo specimen

Towle, I.; Irish, J. D.

10.1101/595595 — paleontology — Posted on 2019-04-01

3020 Parallel Group ICA + ICA: Joint Estimation of Linked Functional Network Variability and Structural Covariation with Application to Schizophrenia

Qi, S.; Sui, J.; Chen, J.; Liu, J.; Jiang, R.; Silva, R.; Iraji, A.; Damaraju, E.; Salman, M.; Lin, D.; Fu, Z.; Zhi, D.; Turner, J. A.; Bustillo, J.; Ford, J. M.; Mathalon, D. H.; Voyvodic, J.; McEwen, S.; Preda, A.; Belger, A.; Potkin, S. G.; Mueller, B. A.; Adali, T.; Calhoun, V. D.

10.1101/595017 — bioinformatics — Posted on 2019-04-01

3021 Moiety Modeling Framework for Deriving Moiety Abundances from Mass Spectrometry Measured Isotopologues

Jin, H.; Moseley, H. N. B.

10.1101/595348 — bioinformatics — Posted on 2019-04-01

3022 The FLAME-accelerated Signalling Tool (FaST): A tool for facile parallelisation of flexible agent-based models of cell signalling

Fullstone, G.; Gutta, C.; Beyer, A.; Rehm, M.

10.1101/595645 — systems biology — Posted on 2019-04-01

3023 History of rare diseases and their genetic causes - a data driven approach

Ehrhart, F.; Willighagen, E.; Kutmon, M.; van Hoften, M.; Bahram Sangani, N.; Curfs, L.; Evelo, C.

10.1101/595819 — systems biology — Posted on 2019-04-01

3024 Brian 2: an intuitive and efficient neural simulator

Stimberg, M.; Brette, R.; Goodman, D.

10.1101/595710 — neuroscience — Posted on 2019-04-01

3025 Neural dynamics of the attentional blink revealed by encoding orientation selectivity during rapid visual presentation

Tang, M. F.; Ford, L.; Arabzadeh, E.; Enns, J. T.; Visser, T. A. W.; Mattingley, J. B.

10.1101/595355 — neuroscience — Posted on 2019-04-01

3026 CRISPR-NSID: an in vivo CRISPR/Cas9 negative selection screen reveals EZH2 as a druggable dependency factor in a genetic desmoid tumor model

Naert, T.; Van Nieuwenhuysen, T.; Demuynck, S.; de Grande, S.; Przybyl, J.; Vuylsteke, M.; Noelanders, R.; Tulkens, D.; Dimitrakopoulou, D.; Creytens, D.; van de Rijn, M.; Savvides, S.; Vleminckx, K.

10.1101/595769 — cancer biology — Posted on 2019-04-01

3027 Neural Correlates of Attitudes and Risk Perception for Food Technology Topics

Davis, T.; LaCour, M.; Beyer, E.; Miller, M.

10.1101/595314 — neuroscience — Posted on 2019-04-01

3028 Chemogenetic activation of excitatory neurons alters hippocampal neurotransmission in a dose-dependent manner

Pati, S.; Salvi, S. S.; Kallianpur, M. V.; Banerjee, A.; Maiti, S.; Clement, J. P.; Vaidya, V. A.

10.1101/595504 — neuroscience — Posted on 2019-04-01

3029 Display of malaria transmission-blocking antigens on chimeric DHBV-derived virus-like particles produced in Hansenula polymorpha

Wetzel, D.; Chan, J.-A.; Suckow, M.; Barbian, A.; Weniger, M.; Jenzelewski, V.; Reiling, L.; Richards, J. S.; Anderson, D. A.; Kouskousis, B.; Palmer, C.; Hanssen, E.; Schembecker, G.; Merz, J.; Beeson, J. G.; Piontek, M.

10.1101/595538 — synthetic biology — Posted on 2019-04-01

3030 Complementary roles for parvalbumin and somatostatin interneurons in the generation of hippocampal gamma oscillations

Mann, E.; Antonoudiou, P.; Tan, Y. L.; Kontou, G.; Upton, A. L.

10.1101/595546 — neuroscience — Posted on 2019-04-01

3031 A novel approach to localize cortical TMS effects

Weise, K.; Numssen, O.; Thielscher, A.; Hartwigsen, G.; Knoesche, T.

10.1101/595603 — neuroscience — Posted on 2019-04-01

3032 Strong spatial genetic structure in a Baltic Sea herbivore due to recent range expansion, multiple bottlenecks and low connectivity

De Wit, P.; Jonsson, P. R.; Pereyra, R. T.; Panova, M.; Andre, C.; Johannesson, K.

10.1101/595629 — evolutionary biology — Posted on 2019-04-01

3033 Population structure and geographically structured reproductive strategies of the haplodiplontic seaweed Dictyota dichotoma

Steen, F.; Verlaque, M.; Dhondt, S.; Vieira, C.; De Clerck, O.

10.1101/595587 — ecology — Posted on 2019-04-01

3034 Domain-specific quantification of prion protein in cerebrospinal fluid by targeted mass spectrometry

10.1101/591487 — neuroscience — Posted on 2019-04-01

3035 Spontaneous back-pain alters randomness in functional connections in large scale brain networks

Matharoo, G. S.; Hashmi, J. A.

10.1101/596163 — biophysics — Posted on 2019-04-01

3036 An inexpensive wireless video recording system for continuous behavioral observations

Weber, W. D.; Fisher, H.

10.1101/596106 — animal behavior and cognition — Posted on 2019-04-01

3037 Neighborhood-statistics reveal complex dynamics of song acquisition in the zebra finch

Kollmorgen, S.; Hahnloser, R.; Mante, V.

10.1101/595512 — neuroscience — Posted on 2019-04-01

3038 The generality of post-antimicrobial treatment persistence of replicatively-attenuated Borrelia burgdorferi in a mouse model

Hodzic, E.; Imai, D. M.; Escobar, E.

10.1101/596122 — microbiology — Posted on 2019-04-01

3039 SSD1 suppresses phenotypes induced by the lack of Elongator-dependent tRNA modifications

Xu, F.; Byström, A.; Johansson, M.

10.1101/596197 — genetics — Posted on 2019-04-01

3040 On the energetics and stability of a minimal fish school

Li, G.; Kolomenskiy, D.; Liu, H.; Thiria, B.; Godoy-Diana, R.

10.1101/596023 — biophysics — Posted on 2019-04-01

3041 Evolution of neuronal anatomy and circuitry in two highly divergent nematode species

Hong, R. L.; Riebesell, M.; Bumbarger, D. J.; Cook, S. J.; Carstensen, H. R.; Sarpolaki, T.; Cochella, L.; Castrejon, J.; Moreno, E.; Sieriebriennikov, B.; Hobert, O.; Sommer, R. J.

10.1101/595025 — neuroscience — Posted on 2019-04-01

3042 Aedes aegypti (Aag2)-derived clonal mosquito cell lines reveal the impact of pre-existing persistent infection with the insect-specific bunyavirus Phasi Charoen-like virus on arbovirus replication

Fredericks, A. C.; Wallace, L. E.; Russell, T. A.; Davidson, A. D.; Fernandez-Sesma, A.; Maringer, K.

10.1101/596205 — microbiology — Posted on 2019-04-01

3043 Mask family proteins ANKHD1 and ANKRD17 regulate YAP nuclear import, stability and phase separation.

Sidor, C.; Borreguero-Munoz, N.; Fletcher, G.; Elbediwy, A.; Vanyai, H.; Guillermin, O.; Thompson, B. J.

10.1101/595439 — developmental biology — Posted on 2019-04-01

3044 The inhibitory effects of butein on cell proliferation and TNF-α-induced CCL2 release in racially different triple negative breast cancer cells

Mendonca, P.; Horton, A.; Bauer, D.; Messeha, S.; Soliman, K. F. A.

10.1101/596080 — cancer biology — Posted on 2019-04-01

3045 Use of human iPSCs and kidney organoids to develop a cysteamine/mTOR inhibition combination therapy to treat cystinosis

Hollywood, J. A.; Przepiorski, A.; Harrison, P. T.; Wolvetang, E. J.; Davidson, A. J.; Holm, T. M.

10.1101/595264 — pathology — Posted on 2019-04-01

3046 Brain dysfunction in chronic pain patients assessed by resting-state electroencephalography

Ta Dinh, S.; Nickel, M.; Tiemann, L.; May, E. S.; Heitmann, H.; Hohn, V. D.; Edenharter, G.; Utpadel-Fischler, D.; Toelle, T.; Sauseng, P.; Gross, J.; Ploner, M.

10.1101/595470 — neuroscience — Posted on 2019-04-01

3047 Ataxin-3 links NOD2 and TLR2 mediated innate immune sensing and metabolism in myeloid cells

Chapman, T.; Corridoni, D.; Shiraishi, S.; Pandey, S.; Aulicino, A.; Wigfield, S.; do Carmo Costa, M.; Thezenas, M.-L.; Paulson, H.; Fischer, R.; Kessler, B. M.; Simmons, A.

10.1101/595637 — immunology — Posted on 2019-04-01

3048 Pitfalls and Remedies for Cross Validation with Multi-trait Genomic Prediction Methods

Runcie, D.; Cheng, H.

10.1101/595397 — genetics — Posted on 2019-04-01

3049 Sex-specific transcriptomic responses to changes in the nutritional environment

Camus, M. F.; Piper, M. W.; Reuter, M.

10.1101/595686 — evolutionary biology — Posted on 2019-04-01

3050 A Theory of Intrinsic Bias in Biology and its Application in Machine Learning and Bioinformatics

Diaz Ochoa, J.

10.1101/595785 — bioinformatics — Posted on 2019-04-01

3051 FilTar: Using RNA-Seq data to improve microRNA target prediction accuracy in animals

Bradley, T.; Moxon, S.

10.1101/595322 — bioinformatics — Posted on 2019-04-01

3052 Spatial and temporal structure of choice representations in primate prefrontal cortex

Kollmorgen, S.; Newsome, W. T.; Mante, V.

10.1101/595520 — neuroscience — Posted on 2019-04-01

3053 Unusual metabolism and hypervariation in the genome of a Gracilibacteria (BD1-5) from an oil degrading community

Sieber, C. M. K.; Paul, B. G.; Castelle, C. J.; Hu, P.; Tringe, S. G.; Valentine, D. L.; Andersen, G. L.; Banfield, J. F.

10.1101/595074 — microbiology — Posted on 2019-04-01

3054 Generation of Temperature Sensitive Mutations with Error-Prone PCR in a Gene Encoding a Component of the Spindle Pole Body in Fission Yeast

Tang, N. H.; Fong, C. S.; Masuda, H.; Jourdain, I.; Yukawa, M.; Toda, T.

10.1101/595447 — genetics — Posted on 2019-04-01

3055 StanDep: capturing transcriptomic variability improves context-specific metabolic models

Joshi, C. J.; Schinn, S.-M.; Richelle, A.; Shamie, I.; O'Rourke, E. J.; Lewis, N.

10.1101/594861 — systems biology — Posted on 2019-04-01

3056 Electrical Energy Storage with Engineered Biological Systems

Salimijazi, F.; Parra, E. A.; Barstow, B.

10.1101/595231 — synthetic biology — Posted on 2019-04-01

3057 Inertial Measurement Unit-Based Estimation of Foot Trajectory for Clinical Gait Analysis

Ono, Y.; Hori, K.; Ora, H.; Hirobe, Y.; Mao, Y.; Sawada, H.; Orimo, S.; Orimo, S.; Miyake, Y.

10.1101/595496 — physiology — Posted on 2019-04-01

3058 The transcription factor Zt107320 affects the dimorphic switch, growth and virulence of the fungal wheat pathogen Zymoseptoria tritici

Habig, M.; Bahena-Garrido, S. M.; Barkmann, F.; Haueisen, J.; Stukenbrock, E. H.

10.1101/595454 — microbiology — Posted on 2019-04-01

3059 Meta-Analysis of the Gene Expression Profiles of Aging Brain Reveals Consistent Increase in Heterogeneity

Isildak, U.; Somel, M.; Thornton, J.; Donertas, H. M.

10.1101/595249 — genomics — Posted on 2019-04-01

3060 Three-phase transitions to reproductive isolation: The roles of utilization mismatch and residual selection

Meszena, G.; Dieckmann, U.

10.1101/595082 — evolutionary biology — Posted on 2019-04-01

3061 Landscape drivers of genomic diversity and divergence in woodland Eucalyptus

Murray, K. D.; Janes, J. K.; Bothwell, H.; Jones, A.; Andrew, R. L.; Borevitz, J. O.

10.1101/590604 — evolutionary biology — Posted on 2019-04-01

3062 Conspecifics, not plant reproductive tissues, reduce omnivore prey consumption

Rinehart, S.; Long, J. D.

10.1101/596015 — ecology — Posted on 2019-04-01

3063 mRNA Degradation Rates Are Coupled to Metabolic Status in Mycobacteria

Vargas-Blanco, D. A.; Zhou, Y.; Gutierrez Zamalloa, L.; Antonelli, T.; Shell, S. S.

10.1101/595199 — microbiology — Posted on 2019-04-01

3064 Complete genome sequence and annotation of the laboratory reference strain Shigella flexneri serovar 5a M90T and genome-wide transcription start site determination

Cervantes-Rivera, R.; Tronnet, S.; Puhar, A.

10.1101/595066 — microbiology — Posted on 2019-04-01

3065 Integrating multiple data sources to fit matrix population models for interacting species

Barraquand, F.; Gimenez, O.

10.1101/594986 — ecology — Posted on 2019-04-01

3066 Is the addition of higher-order interactions in ecological models increasing the understanding of ecological dynamics?

AlAdwani, M.; Saavedra, S.

10.1101/595140 — ecology — Posted on 2019-04-01

3067 Larvicidal evaluation of the Origanum majorana L. Essential Oil against the larvae of the Aedes aegypti mosquito

Chaves, R. d. S. B.; Martins, R. L.; Rodrigues, A. B. L.; Rabelo, E. d. M.; Farias, A. L. F.; Araujo, C. M. d. C. V.; Sobral, T. F.; Galardo, A. K. R.; de Almeida, S. S. M. d. S.

10.1101/595900 — physiology — Posted on 2019-04-01

3068 The human microbiota is associated with cardiometabolic risk across the epidemiologic transition

Fei, N.; Bernabe, B. P.; Lie, L.; Baghdan, D.; Bedu-Addo, K.; Plange-Rhule, J.; Forrester, T. E.; Lambert, E. V.; Bovet, P.; Gottel, N.; Riesen, W.; Korte, W.; Kliethermes, S. A. K. A.; Luke, A.; T. Layden, B. T.; Gilbert, J. A.; Dugas, L. R.

10.1101/595934 — microbiology — Posted on 2019-04-01

3069 Projected changes of alpine grassland carbon dynamics in response to climate change and elevated CO2 concentrations under Representative Concentration Pathways (RCP) scenarios

Han, P.; Lin, X.; Zhang, W.; Wang, G.

10.1101/595926 — ecology — Posted on 2019-04-01

3070 Targeting the dysfunctional mitochondrial respiration in drug resistant B-cell acute lymphoblastic leukemia

Nair, R. R.; Piktel, D.; Thomas, P.; Hathaway, Q.; Rellick, S.; Saralkar, P.; Martin, K.; Geldenhuys, W. J.; Hollander, J.; Gibson, L.

10.1101/595959 — cancer biology — Posted on 2019-04-01

3071 Association between thyroid hormones and HOMA-IR in Saudi-obese women with metabolic syndrome

Binobead, M. A.; Al Badr, N. A.; Al-Qahtani, W. H.; AlSedairy, S. A.; Albrahim, T. I.; Alhussain, M. H.; Aljurbua, T. A.; Arzoo, S.; Al-Qahtani, W. S.

10.1101/595884 — biochemistry — Posted on 2019-04-01

3072 Risk variant in miR-544a binding site in CCDC170 is associated with osteoporosis

Liu, X.; Wang, Y.; Tan, Q.; He, Y.; Zhao, X.

10.1101/595918 — genetics — Posted on 2019-04-01

3073 The inherent multidimensionality of temporal variability: How common and rare species shape stability patterns

Arnoldi, J.-F.; Loreau, M.; Haegeman, B.

10.1101/431296 — ecology — Posted on 2019-04-01

3074 The mouse HP1 proteins are essential for preventing liver tumorigenesis

Saksouk, N.; Hajdari, S.; Pratlong, M.; Barrachina, C.; Graber, C.; Zavoriti, A.; Sarrazin, A.; Pirot, N.; Noël, J.-Y.; Khellaf, L.; Fabbrizio, E.; Julien, E.; Cammas, F. M.