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Archive, 2023-02

2 Mitochondrial translocation of TFEB regulates complex I and inflammation
Calabrese, C.; Nolte, H.; Pitman, M. R.; Ganesan, R.; Lampe, P.; Laboy, R.; Ripa, R.; Fischer, J.; Chipurupalli, S.; Gutierrez, S.; Polara, R.; Thomas, D.; Pitson, S. M.; Antebi, A.; Robinson, N.
10.1101/2023.02.27.530219 — cell biology — Posted on 2023-02-28
4 New insight into the Germline Genes and CDR3 Repertoire of the TCR-beta chain in Chiroptera
Zhou, H.; Yao, X. S.; Li, J.; Ma, Q. Q.; Liu, L. Y.; Zhou, D. W.; Wu, Y. J.; Wang, X. L.; Zhou, J.; Ma, L.
10.1101/2022.12.05.519110 — immunology — Posted on 2023-02-28
5 Locus coeruleus neuromelanin predicts ease of attaining and maintaining neural states of high attentiveness
Hussain, S.; Menchaca, I.; Shalchy, M. A.; Yaghoubi, K.; langley, j.; Seitz, A.; Hu, X.; Peters, M. A. K.
10.1101/2022.03.07.483289 — neuroscience — Posted on 2023-02-28
7 The WalKR two-component regulator coordinates cell wall homeostasis with DNA replication in Staphylococcus aureus
Sharkey, L. K. R.; Guerillot, R.; Walsh, C. J.; Turner, A. M.; Lee, J. Y. H.; Neville, S. L.; Klatt, S.; Baines, S. L.; Pidot, S. J.; Rossello, F. J.; Seeman, T.; McWilliam, H.; Cho, E.; Howden, B. P.; McDevitt, C. A.; Hachani, A.; Stinear, T. P.; Monk, I. R.
10.1101/2023.02.27.530350 — microbiology — Posted on 2023-02-28
10 The influence of Sex on microRNA expression in Human Skeletal Muscle
Hiam, D.; Landen, S.; Jacques, M.; Voisin, S.; Lamon, S.; Eynon, N.
10.1101/2023.02.27.530361 — physiology — Posted on 2023-02-28
11 Transposable element RNA dysregulation in mutant KRAS(G12C) 3D lung cancer spheroids
Carrillo, D.; Reggiardo, R. E.; Lim, J.; Mantalas, G.; Peddu, V.; Kim, D. H.
10.1101/2023.02.27.530369 — genomics — Posted on 2023-02-28
12 The Impact of Gulf Stream Frontal Eddies on Ecology and Biogeochemistry near Cape Hatteras
Gray, P. C.; Gronniger, J.; Savelyev, I.; Dale, J.; Niebergall, A. K.; Cassar, N.; Windle, A. E.; Hunt, D. E.; Johnson, Z.; Levy, M.; Taylor, C.; Bourdin, G.; Blawas, A.; Lohmann, A.; Silsbe, G.; Johnston, D. W.
10.1101/2023.02.22.529409 — ecology — Posted on 2023-02-28
14 Atopic dermatitis complicated by recurrent eczema herpeticum is characterized by multiple, concurrent epidermal inflammatory endotypes
Jackson, N. D.; Dyjack, N.; Goleva, E.; Bin, L.; Montgomery, M. T.; Rios, C.; Everman, J. L.; Taylor, P.; Bronchick, C.; Richers, B. N.; Leung, D. Y.; Seibold, M. A.
10.1101/2023.02.27.530316 — molecular biology — Posted on 2023-02-28
16 Candida auris evades innate immunity by using metabolic strategies to escape and kill macrophages while avoiding antimicrobial inflammation
Weerasinghe, H. C.; Simm, C.; Djajawi, T.; Tedja, I.; Lo, T. L.; Shasha, D.; Mizrahi, N.; Olivier, F. A. B.; Speir, M.; Lawlor, K. E.; Ben-Ami, R.; Traven, A.
10.1101/2023.02.28.529319 — microbiology — Posted on 2023-02-28
18 Identification of efflux substrates using a riboswitch-based reporter in Pseudomonas aeruginosa
Urdaneta-Paez, V.; Hamchand, R.; Anthony, K. G.; Crawford, J.; Sutherland, A. G.; Kazmierczak, B. I.
10.1101/2023.02.27.530370 — microbiology — Posted on 2023-02-28
19 Live-cell Fluorescence Microscopy of HSV-1 Cellular Egress by Exocytosis
Bergeman, M. H.; Hernandez, M. Q.; Diefenderfer, J.; Drewes, J. A.; Velarde, K.; Tierney, W. M.; Hogue, I. B.
10.1101/2023.02.27.530373 — microbiology — Posted on 2023-02-28
20 Prolonging Genetic Circuit Stability through Adaptive Evolution of Overlapping Genes
Chlebek, J. L.; Leonard, S. P.; Kang-Yun, C.; Yung, M. C.; Ricci, D. P.; Jiao, Y.; Park, D. M.
10.1101/2023.02.27.530340 — synthetic biology — Posted on 2023-02-28
21 Rolosense: Mechanical detection of SARS-CoV-2 using a DNA-based motor
Piranej, S.; Zhang, L.; Bazrafshan, A.; Marin, M.; Melikyan, G. B.; Salaita, K.
10.1101/2023.02.27.530294 — biophysics — Posted on 2023-02-28
23 Hypercholesterolemia aggravates in-stent restenosis in rabbits: a mitigating effect of stent surface modification with CD47-derived peptide.
Fishbein, I.; Inamdar, V. V.; Alferiev, I. S.; Bratinov, G.; Zviman, M. M.; Yekhilevsky, A.; Nagaswami, C.; Gardiner, K. L.; Levy, R. J.; Stachelek, S. J.
10.1101/2023.02.27.530304 — bioengineering — Posted on 2023-02-28
24 The chemical landscape of the human ribosome at 1.67 A resolution
Faille, A.; Dent, K. C.; Pellegrino, S.; Jaako, P.; Warren, A. J.
10.1101/2023.02.28.530191 — biochemistry — Posted on 2023-02-28
26 MEMO1 is a Metal Containing Regulator of Iron Homeostasis in Cancer Cells
Dolgova, N.; Uhlemann, E.-M. E.; Boniecki, M. T.; Vizeacoumar, F. S.; Ralle, M.; Tonelli, M.; Abbas, S. A.; Patry, J.; Elhasasna, H.; Freywald, A.; Vizeacoumar, F.; Dmitriev, O. Y.
10.1101/2023.02.28.530460 — biochemistry — Posted on 2023-02-28
34 Structural basis for DARC binding in reticulocyte invasion by Plasmodium vivax
Moskovitz, R.; Pholcharee, T.; DonVito, S.; Guloglu, B.; Lowe, E.; Mohring, F.; Moon, R. W.; Higgins, M. K.
10.1101/2023.02.28.530453 — microbiology — Posted on 2023-02-28
40 The paracaspase MALT1 controls cholesterol homeostasis in glioblastoma stem-like cells through lysosome proteome shaping
Maghe, C.; Trillet, K.; Gregoire, G. A.; Kerherve, M.; Merlet, L.; Jacobs, K. A.; Bidere, N.; Gavard, J.
10.1101/2023.02.27.530259 — cancer biology — Posted on 2023-02-28
43 Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages
Zarrow, J. E.; Alli-Oluwafuyi, A.-M.; Youwakim, C. M.; Kim, K.; Jenkins, A. N.; Suero, I. C.; Jones, M. R.; Mashhadi, Z.; Mackie, K. P.; Waterson, A. G.; Doran, A. C.; Sulikowski, G. A.; Davies, S. S.
10.1101/2023.01.25.525554 — biochemistry — Posted on 2023-02-28
44 Behavioral dissection of hunger states in Drosophila
Weaver, K. J.; Raju, S.; Rucker, R. A.; Chakraborty, T.; Holt, R. A.; Pletcher, S.
10.1101/2022.11.11.516105 — animal behavior and cognition — Posted on 2023-02-28
47 Transcriptomic responses of sponge holobionts to in situ, seasonal anoxia and hypoxia
Strehlow, B. W.; Schuster, A.; Francis, W. R.; Eckford-Soper, L.; Kraft, B.; McAllen, R.; Nielsen, R.; Mandrup, S.; Canfield, D. E.
10.1101/2023.02.27.530229 — ecology — Posted on 2023-02-28
48 Phase Separation of a Nodulin Sec14-like protein Maintains Auxin Efflux Carrier Polarity at Arabidopsis Plasma Membranes
Liu, C.; Mentzelopoulou, A.; Papagavriil, F.; Ramachandran, P.; Perraki, A.; Claus, L.; Barg, S.; Doermann, P.; Jaillais, Y.; Johnen, P.; Russinova, E.; Gizeli, E.; Schaaf, G.; Moschou, P. N.
10.1101/2022.03.26.485938 — cell biology — Posted on 2023-02-28
50 Mass-immigration shapes the antibiotic resistome of wastewater treatment plants
Zhang, L.; Adyari, B.; Hou, L.; Yang, X.; Gad, M.; Wang, Y.; Ma, C.; Sun, Q.; Yu, C.-P.; Hu, A.
10.1101/2023.02.27.530348 — microbiology — Posted on 2023-02-28
52 Conflict during learning reconfigures the neural representation of positive valence and approach behaviour
Molina-Garcia, L.; Colinas-Fischer, S.; Benavides-Laconcha, S.; Lin, L.; Clark, E.; Treloar, N. J.; Garcia-Minaur-Ortiz, B.; Barnes, C. P.; Barrios, A.
10.1101/2023.02.03.527017 — neuroscience — Posted on 2023-02-28
54 From Policy to Practice: Tracking an Open Science Funding Initiative
Ratan, K.; Dumanis, S. B.; McIntosh, S.; Shah, H. V.; Lewis, M.; Vines, T. H.; Schekman, R.; Riley, E. A. U.
10.1101/2023.02.27.530238 — scientific communication and education — Posted on 2023-02-28
57 A community driven GWAS summary statistics standard
Hayhurst, J.; Buniello, A.; Harris, L.; Mosaku, A.; Chang, C.; Gignoux, C. R.; Hatzikotoulas, K.; Karim, M. A.; Lambert, S. A.; Lyon, M.; McMahon, A.; Okada, Y.; Pirastu, N.; Rayner, N. W.; Schwartzentruber, J.; Vaughan, R.; Verma, S.; Wilder, S. P.; Cunningham, F.; Hindorff, L.; Wiley, K.; Parkinson, H.; Barroso, I.
10.1101/2022.07.15.500230 — bioinformatics — Posted on 2023-02-28
59 Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet
Viner, C.; Ishak, C. A.; Johnson, J.; Walker, N. J.; Shi, H.; Sjöberg-Herrera, M. K.; Shen, S. Y.; Lardo, S. M.; Adams, D. J.; Ferguson-Smith, A. C.; De Carvalho, D. D.; Hainer, S. J.; Bailey, T. L.; Hoffman, M. M.
10.1101/043794 — bioinformatics — Posted on 2023-02-28
62 Using visual scores and categorical data for genomic prediction of complex traits in breeding programs
Ferreira Azevedo, C.; Ferrao, L. F. V.; Benevenuto, J.; Resende, M. D.; Nascimento, M.; Nascimento, A. C.; Munoz, P.
10.1101/2023.02.27.530308 — genetics — Posted on 2023-02-28
65 Parasites make hosts more profitable but less available to predators
Prosnier, L.; Loeuille, N.; Hulot, F. D.; Renault, D.; Piscart, C.; Bicocchi, B.; Deparis, M.; Lam, M.; Medoc, V.
10.1101/2022.02.08.479552 — ecology — Posted on 2023-02-28
69 The histone methyltransferase DOT1L regulates chromatin reorganization and gene expression during the postmeiotic differentiation of male germ cells
Blanco, M.; El Khattabi, L.; Gobe, C.; Crespo, M.; Coulee, M.; de la Iglesia, A.; Ialy-Radio, C.; Lapoujade, C.; Givelet, M.; Delessard, M.; Seller Corona, I.; Yamaguchi, K.; Vernet, N.; van Leeuwen, F.; Lermine, A.; Okada, Y.; Daveau, R.; Oliva, R.; Fouchet, P.; Ziyyat, A.; Pflieger, D.; Cocquet, J.
10.1101/2022.10.17.512530 — molecular biology — Posted on 2023-02-28
70 Deep divergence and genomic diversification of gut symbionts of neotropical stingless bees
Sarton-Loheac, G.; Nunes da Silva, C. G.; Mazel, F.; Baud, G.; de Bakker, V.; Das, S.; El Chazli, Y.; Ellegaard, K. M.; Garcia-Garcera, M.; Glover, N. M.; Liberti, J. M.; Nacif Marcal, L.; Prasad, A.; Somerville, V.; SAGE class 2019-2020 and 2020-2021, ; Bonilla Rosso, G.; Engel, P.
10.1101/2022.12.08.519137 — microbiology — Posted on 2023-02-28
71 Genetic influences vary by age and sex: Trajectories of the association of cholinergic system variants and theta band event related oscillations
Chorlian, D. B.; Meyers, J. L.; Manz, N.; Zhang, J.; Kamarajan, C.; Pandey, A.; Wang, J.-C.; Plawecki, M.; Edenberg, H.; Goate, A.; Tischfield, J.; Porjesz, B.
10.1101/2023.02.27.530318 — neuroscience — Posted on 2023-02-28
73 A Novel Protein for the Bioremediation of Gadolinium Waste
Lee, H. D.; Grady, C. J.; Krell, K.; Strebeck, C.; Good, N. M.; Martinez-Gomez, N. C.; Gilad, A.
10.1101/2023.01.05.522788 — bioengineering — Posted on 2023-02-28
74 Improving the annotation of the cattle genome by annotating transcription start sites in a diverse set of tissues and populations using CAGE sequencing
Salavati, M.; BovReg consortium, ; Clark, R.; Becker, D.; Kuehn, C.; Plastow, G. S.; Dupont, S.; Moreira, G. C. M.; Charlier, C.; Clark, E. L.
10.1101/2023.02.27.530265 — genomics — Posted on 2023-02-28
75 N-Glycosylation is a Potent Regulator of Prion Protein Neurotoxicity
Schilling, K. M.; Jorwal, P.; Ubilla-Rodriguez, N. C.; Assafa, T. E.; Gatdula, J. R. P.; Harris, D. A.; Millhauser, G. L.
10.1101/2023.02.25.530047 — neuroscience — Posted on 2023-02-28
83 Analyzing genomic alterations involved in fluoroquinolone-resistant development in Staphylococcus aureus
Huynh, T. Q.; Tran, V. N.; Thai, V. C.; Nguyen, H. A.; Nguyen, N. T. G.; Surian, N. U.; Chen, S.; Nguyen, T. T. H.
10.1101/2023.02.26.530158 — microbiology — Posted on 2023-02-28
85 Characterization of early white matter changes in CADASIL using microscopic diffusion imaging and relaxometry
Barriere, D.; Uszynski, I.; Rajani, R.; Gueniot, F.; Domenga-Denier, V.; Boumezbeur, F.; Poupon, C.; Joutel, A.
10.1101/2023.02.27.530286 — neuroscience — Posted on 2023-02-28
87 Cautionary note on ribonuclease activity of recombinant PR-10 proteins
Longsaward, R.; Sanguankiattichai, N.; Viboonjun, U.; van der Hoorn, R.
10.1101/2023.02.27.529914 — plant biology — Posted on 2023-02-28
89 Radiation-induced persistent DNA damage response and late toxicity in cardiac tissue
Shigemori, K.; Jiang, Y.; Martin, J. C.; Hawkins, M. A.; Ryan, A. J.; Parkes, E. E.
10.1101/2023.02.27.530210 — cancer biology — Posted on 2023-02-28
90 Uncovering the hidden threat: single-organoid analysis reveals clinically relevant treatment-resistant and invasive subclones in pancreatic cancer
Le Compte, M.; Cardenas De La Hoz, E.; Peeters, S.; Rodrigues Fortes, F.; Hermans, C.; Domen, A.; Smits, E.; Lardon, F.; Vandamme, T.; Lin, A.; Vanlanduit, S.; Roeyen, G.; Van Laere, S.; Prenen, H.; Peeters, M.; Deben, C.
10.1101/2023.02.27.530080 — cancer biology — Posted on 2023-02-28
92 Identification of a pharmaceutical biostasis inducer that slows metabolism in multiple vertebrates that do not hibernate
Sperry, M. M.; Charrez, B.; Fotowat, H.; Gardner, E.; Pilobello, K.; Izadifar, Z.; Lin, T.; Kuelker, A.; Kaki, S.; Lewandowski, M.; Lightbown, S.; Martinez, R.; Marquez, S.; Sesay, A.; Shcherbina, K.; Takeda, T.; Andrijauskaite, K.; Cisneros, E.; Lopez, R.; Cano, I.; Maxwell, Z.; Veraza, R.; Bunegin, L.; Percival, T. J.; Yracheta, J.; Pena, J. J.; Wood, D. M.; Homas, Z. T.; Hinshaw, C. J.; Cox-Hinshaw, J.; Parry, O. G.; Sleeter, J. J.; Weitzel, E.; Levin, M.; Super, M.; Novak, R.; Ingber, D. E.
10.1101/2023.02.27.530270 — bioengineering — Posted on 2023-02-28
93 Continuous, long-term crawling behavior characterized by a robotic transport system
Yu, J.; Dancausse, S.; Paz, M.; Faderin, T.; Gaviria, M.; Shomar, J. W.; Zucker, D.; Venkatachalam, V.; Klein, M.
10.1101/2023.02.27.530235 — animal behavior and cognition — Posted on 2023-02-28
94 SMCHD1 loss triggers DUX4 expression by disrupting splicing in FSHD2
Engal, E.; Sharma, A.; Taqatqa, N.; Bentata, M.; Jaffe-Herman, S.; Geminder, O.; Lewis, R.; Gotkine, M.; Salton, M.; Drier, Y.
10.1101/2023.02.27.530258 — genomics — Posted on 2023-02-28
97 Forest cover is more important than its integrity or configuration of the landscape in determining the habitat use of mammals in a modified landscape in Colombia
Pardo, L. E.; Gomez-Valencia, B.; Deere, N.; Herrera Varon, Y.; Soto, C.; Noguera-Urbano, E. A.; Sanchez-Clavijo, L. M.; Romero, L.; Diaz-Pulido, A.; Ochoa-Quintero, J. M.
10.1101/2023.02.27.530271 — ecology — Posted on 2023-02-28
98 Engineered Immunogens to Expose Conserved Epitopes Targeted by Broad Coronavirus Antibodies
Kapingidza, B.; Marston, D. J.; Harris, C.; Wrapp, D.; Winters, K.; Rhodes, B.; Vure, P.; Woods, C. W.; Petzold, E. A.; Walter, E. B.; Parks, R.; Barr, M.; Yin, Q.; Cain, D. W.; Wiehe, K.; Saunders, K. O.; Haynes, B. F.; Azoitei, M. L.
10.1101/2023.02.27.530277 — immunology — Posted on 2023-02-28
99 Bcl2 supports survival and metabolic fitness of quiescent tissue-resident ILC3
King, J. I.; Melo-Gonzalez, F.; Malengier-Devlies, B.; Tacho-Pinot, R.; Magalhaes, M. S.; Hodge, S. H.; Romero Ros, X.; Gentek, R.; Hepworth, M. R.
10.1101/2023.02.27.528945 — immunology — Posted on 2023-02-28
100 Detecting the effect of genetic diversity on brain composition in an Alzheimer's disease mouse model
Gurdon, B.; Yates, S. C.; Csucs, G.; Groeneboom, N.; Hadad, N.; Telpoukhovskaia, M.; Ouellette, A.; Ouellette, T.; O'Connell, K.; Singh, S.; Murdy, T.; Merchant, E.; Bjerke, I. E.; Kleven, H.; Schlegel, U.; Leergaard, T. B.; Puchades, M.; Bjaalie, J. G.; Kaczorowski, C.
10.1101/2023.02.27.530226 — neuroscience — Posted on 2023-02-28
104 Data-Driven Screening to Infer Metabolic Modulators of the Cancer Epigenome
Campit, S.; Bhowmick, R.; Lu, T.; Saoji, A.; Jin, R.; Robida, A.; Chandrasekaran, S.
10.1101/2023.02.27.530260 — systems biology — Posted on 2023-02-28
105 What mycologists should talk about when they are talking about the International Code of Nomenclature for algae, fungi, and plants
Nilsson, H. R.; Ryberg, M.; Wurzbacher, C.; Tedersoo, L.; Anslan, S.; Polme, S.; Spirin, V.; Mikryukov, V.; Svantesson, S.; Hartmann, M.; Lennartsdotter, C.; Belford, P.; Khomich, M.; Retter, A.; Corcoll, N.; Martinez, D. G.; Jansson, T. A.; Ghobad-Nejhad, M.; Vu, D.; Sanchez-Garcia, M.; Kristiansson, E.; Abarenkov, K.
10.1101/2023.02.25.529721 — scientific communication and education — Posted on 2023-02-28
106 From Policy to Practice: Tracking an Open Science Funding Initiative
Ratan, K.; McIntosh, S.; Shah, H. V.; Lewis, M.; Dumanis, S. B.; Vines, T. H.; Schekman, R.; Riley, E. A. U.
10.1101/2023.02.27.530238 — scientific communication and education — Posted on 2023-02-28
107 Neutralizing antibody levels and epidemiological information of patients with breakthrough COVID-19 infection in Toyama, Japan
Tani, H.; Inasaki, N.; Shimada, T.; Saga, Y.; Kaya, H.; Maruyama, Y.; Matano, S.; Itoh, H.; Kashii, T.; Yamazaki, E.; Yazawa, S.; Itamochi, M.; Oishi, K.
10.1101/2023.02.27.530346 — microbiology — Posted on 2023-02-28
111 Neonatal brain dynamic functional connectivity: impact of preterm birth and association with early childhood neurodevelopment
Franca, L. G. S.; Ciarrusta, J.; Gale-Grant, O.; Fenn-Moltu, S.; Fitzgibbon, S. P.; Chew, A.; Falconer, S.; Dimitrova, R.; Cordero-Grande, L.; Price, A. N.; Hughes, E.; O'Muircheartaigh, J.; Duff, E.; Tuulari, J. J.; Deco, G.; Counsell, S. J.; Hajnal, J. V.; Nosarti, C.; Arichi, T.; Edwards, D.; McAlonan, G.; Batalle, D.
10.1101/2022.11.16.516610 — neuroscience — Posted on 2023-02-28
113 Extensive profiling of histidine-containing dipeptides reveals species- and tissue-specific distribution and metabolism in mice, rats and humans
Van der Stede, T.; Spaas, J.; de Jager, S.; De Brandt, J.; Hansen, C.; Stautemas, J.; Vercammen, B.; De Baere, S.; Croubels, S.; Van Assche, C.-H.; Cillero Pastor, B.; Vandenbosch, M.; Van Thienen, R.; Verboven, K.; Hansen, D.; Bove, T.; Lapauw, B.; Van Praet, C.; Decaestecker, K.; Vanaudenaerde, B.; Eijnde, B. O.; Gliemann, L.; Hellsten, Y.; Derave, W.
10.1101/2023.02.16.528841 — physiology — Posted on 2023-02-28
114 Deep topographic proteomics of a human brain tumour
Davis, S.; Scott, C.; Oetjen, J.; Charles, P. D.; Kessler, B. M.; Ansorge, O.; Fischer, R.
10.1101/2022.03.21.485119 — cancer biology — Posted on 2023-02-28
115 A Step Towards Generalisability: Training a Machine Learning Scoring Function for Structure-Based Virtual Screening
Scantlebury, J.; Vost, L.; Carbery, A.; Hadfield, T. E.; Turnbull, O. M.; Brown, N.; Chenthamarakshan, V.; Das, P.; Grosjean, H.; von Delft, F.; Deane, C. M.
10.1101/2022.10.28.511712 — bioinformatics — Posted on 2023-02-28
116 A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein
Thijssen, V.; Hurdiss, D. L.; Debski-Antoniak, O. J.; Spence, M. A.; Franck, C.; Norman, A.; Aggarwal, A.; Mokiem, N. J.; van Dongen, D. A. A.; Vermeir, S. W.; Liu, M.; Li, W.; Chatziandreou, M.; Donselaar, T.; Du, W.; Drulyte, I.; Bosch, B. J.; Snijder, J.; Turville, S. G.; Payne, R. J.; Jackson, C. J.; van Kuppeveld, F. J. M.; Jongkees, S. A. K.
10.1101/2022.11.11.516114 — biochemistry — Posted on 2023-02-28
117 At-home bacteria collection using CandyCollect, a lollipop-inspired device
Tu, W.-c.; McManamen, A. M.; Su, X.; Jeacopello, I.; Takezawa, M. G.; Hieber, D. L.; Hassan, G. W.; Lee, U. N.; Anana, E. V.; Locknane, M. P.; Stephenson, M. W.; Shinkawa, V. A. M.; Wald, E. R.; DeMuri, G. P.; Adams, K.; Berthier, E.; Thongpang, S.; Theberge, A. B.
10.1101/2023.01.14.524039 — biochemistry — Posted on 2023-02-28
118 A quantitative theory for genomic offset statistics
Gain, C.; Rhone, B.; CUBRY, P.; Salazar, I.; Forbes, F.; Vigouroux, y.; Jay, F.; Francois, O.
10.1101/2023.01.02.522469 — evolutionary biology — Posted on 2023-02-28
119 mRNA decapping machinery targets LBD3/ASL9 transcripts to mediate developmental changes in Arabidopsis
Zuo, Z.; Roux, M. E.; Chevalier, J.; Dagdas, Y.; Yamashino, T.; Hojgaard, S. D.; Knight, E.; Ostergaard, L.; Rodriguez, E.; petersen, m.
10.1101/2022.07.06.499076 — developmental biology — Posted on 2023-02-28
120 Engineered ketocarotenoid biosynthesis in the polyextremophilic red microalga Cyanidioschyzon merolae 10D
Seger, M.; Mammadova, F.; Villegas-Valencia, M.; Bastos de Freitas, B.; Cheng, C.; Isachsen, I.; Hemstreet, H.; Abualsaud, F.; Boring, M.; Lammers, P. J.; Lauersen, K. J.
10.1101/2023.02.27.530181 — bioengineering — Posted on 2023-02-28
121 The genome of the toxic invasive species Heracleum sosnowskyi carries an increased number of genes despite the absence of recent whole-genome duplications
Schelkunov, M. I.; Shtratnikova, V. Y.; Klepikova, A. V.; Makarenko, M. S.; Omelchenko, D. O.; Novikova, L. A.; Obukhova, E. N.; Bogdanov, V. P.; Penin, A. A.; Logacheva, M. D.
10.1101/2023.02.14.528432 — genomics — Posted on 2023-02-28
123 SIRT6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes
Copp, M. E.; Shine, J.; Brown, H. L.; Nimmala, K. R.; Chubinskaya, S.; Collins, J. A.; Loeser, R.; Diekman, B. O.
10.1101/2023.02.27.530205 — cell biology — Posted on 2023-02-28
124 CRISPR/Cas9-based edition of frataxin gene in Dictyostelium discoideum for Friedreich's Ataxia disease modeling
Gentili, H. G.; Pignataro, M. F.; Olmos, J.; Pavan, M. F.; Ibanez, L. I.; Santos, J.; Velazquez, F.
10.1101/2023.02.27.530330 — cell biology — Posted on 2023-02-28
126 Mitochondrial translocation of TFEB regulates complex I and inflammation
Calabrese, C.; Nolte, H.; Pitman, M. R.; Ganesan, R.; Lampe, P.; Laboy, R.; Ripa, R.; Fischer, J.; Chipurupalli, S.; Gutierrez, S.; Polara, R.; Thomas, D.; Pitson, S. M.; Antebi, A.; Robinson, N.
10.1101/2023.02.27.530219 — cell biology — Posted on 2023-02-28
132 A comparative study of in vitro air-liquid interface culture models of the human airway epithelium evaluating cellular heterogeneity and gene expression at single cell resolution
Prescott, R. A.; Pankow, A. P.; de Vries, M.; Crosse, K.; Patel, R. S.; Alu, M.; Loomis, C.; Torres, V.; Koralov, S. B.; Ivanova, E. N.; Dittmann, M.; Rosenberg, B. R.
10.1101/2023.02.27.530299 — cell biology — Posted on 2023-02-28
134 Function of ERphagy receptors is regulated via phosphorylation-dependent ubiquitination pathways
Berkane, R.; Ho-Xuan, H.; Glogger, M.; Sanz-Martinez, P.; Cano-Franco, S.; Juretschke, T.; Gonzales Cardenas, A.; Glaesner, T.; Beli, P.; Husnjak, K.; Doetsch, V.; Grumati, P.; Heilemann, M.; Stolz, A.
10.1101/2023.02.27.530364 — cell biology — Posted on 2023-02-28
136 The allotetraploid Nicotiana tabacum genome and GenBank genomics highlight the genomic features, genetic diversity and regulation of morphological, metabolic and disease-resistance traits
Zan, Y.; Chen, S.; Ren, M.; Liu, G.; Liu, Y.; Si, H.; Liu, Z.; Liu, D.; Zhang, X.; Tong, Y.; Li, Y.; Jiang, C.; Wen, L.; Xiao, Z.; Sun, Y.; Geng, R.; Feng, Q.; Wang, Y.; Ye, G.; Fang, L.; Chen, Y.; Cheng, L.; Yang, A.
10.1101/2023.02.21.529366 — genetics — Posted on 2023-02-28
137 Joint testing of rare variant burden scores using non-negative least squares
Ziyatdinov, A.; Mbatchou, J.; Marcketta, A.; Backman, J.; Gaynor, S.; Zou, Y.; Joseph, T.; Geraghty, B.; Herman, J.; Watanabe, K.; Ghosh, A.; Kosmicki, J.; Locke, A.; Regeneron Genetics Center, ; Thornton, T.; Kang, H. M.; Ferreira, M.; Baras, A.; Abecasis, G.; Marchini, J.
10.1101/2023.02.22.529560 — genetics — Posted on 2023-02-28
141 The Drosophila chemokine-like Orion bridges phosphatidylserine and Draper in phagocytosis of neurons
Ji, H.; Wang, B.; Shen, Y.; Labib, D.; Lei, J.; Chen, X.; Sapar, M.; Boulanger, A.; Dura, J.-M.; Han, C.
10.1101/2022.02.11.480148 — neuroscience — Posted on 2023-02-28
143 Dopamine dysregulation in Parkinson's disease flattens the pleasurable urge to move to musical rhythms
Pando-Naude, V.; Matthews, T. E.; Hojlund, A.; Jakobsen, S.; Ostergaard, K.; Johnsen, E.; Garza-Villarreal, E. A.; Witek, M.; Penhune, V. B.; Vuust, P.
10.1101/2023.02.27.530174 — neuroscience — Posted on 2023-02-28
144 White matter and literacy: a dynamic system in flux
Roy, E.; Richie-Halford, A.; Kruper, J.; Narayan, M.; Bloom, D.; Nedelec, P.; Sugrue, L. P.; Rauschecker, A.; Brown, T. T.; Jernigan, T. L.; McCandliss, B. D.; Rokem, A.; Yeatman, J. D.
10.1101/2022.06.21.497048 — neuroscience — Posted on 2023-02-28
147 Distinct disease mutations in DNMT3A result in a spectrum of behavioral, epigenetic, and transcriptional deficits
Beard, D. C.; Zhang, X.; Wu, D. Y.; Martin, J. R.; Hamagami, N.; Swift, R. G.; McCullough, K. B.; Ge, X.; Bell-Hensley, A.; Zheng, H.; Lawrence, A. B.; Hill, C. A.; Papouin, T.; McAlinden, A.; Garbow, J. R.; Dougherty, J. D.; Maloney, S. E.; Gabel, H. W.
10.1101/2023.02.27.530041 — neuroscience — Posted on 2023-02-28
148 Lidocaine Induces Apoptosis in Head and Neck Squamous Cell Carcinoma Cells Through Activation of Bitter Taste Receptor T2R14
Miller, Z. A.; Jolivert, J. F.; Ma, R. Z.; Muthuswami, S.; Mueller, A.; McMahon, D. B.; Carey, R. M.; Lee, R. J.
10.1101/2022.11.22.517413 — cancer biology — Posted on 2023-02-28
153 Microwell-Based Flow Culture Increases Viability and Restores Drug Response in Prostate Cancer Spheroids
Payne, M.; Ho, S.; Hashimoto, T.; Imboden, S.; Diaz, J.; Lee, B.; Rupert, M.; Cai, N.; Goldstein, A.; Lin, N.
10.1101/2022.06.28.498007 — bioengineering — Posted on 2023-02-28
157 A novel antifolate suppresses growth of FPGS-deficient cells and overcomes methotrexate resistance
van der Krift, F.; Zijlmans, D. W.; Shukla, R.; Javed, A.; Koukos, P. I.; Schwarz, L. L. E.; Timmermans-Sprang, E. P. M.; Maas, P. E. M.; Gahtory, D.; van den Nieuwboer, M.; Mol, J. A.; Strous, G. J.; Bonvin, A. M. J. J.; Veldhuizen, E. J. A.; van der Stelt, M.; Weingarth, M.; Vermeulen, M.; Klumperman, J.; Maurice, M. M.
10.1101/2023.02.26.530079 — biochemistry — Posted on 2023-02-28
158 oskar acts with the transcription factor Creb to regulate long-term memory in crickets
Kulkarni, A.; Ewen-Campen, B. S.; Terao, K.; Matsumoto, Y.; Li, Y.; Watanabe, T.; Kao, J.; Parhad, S. S.; Ylla, G.; Mizunami, M.; Extavour, C. G.
10.1101/2022.10.24.513429 — animal behavior and cognition — Posted on 2023-02-28
159 In vitro reconstitution of chromatin domains
Quililan, K.; Oberbeckmann, E.; Cramer, P.; Oudelaar, A. M.
10.1101/2023.02.27.530214 — genomics — Posted on 2023-02-28
163 A subset of viruses thrives following microbial resuscitation during rewetting of a seasonally dry California grassland soil
Nicolas, A. M.; Sieradzki, E. T.; Pett-Ridge, J.; Banfield, J. F.; Taga, M. E.; Firestone, M. K.; Blazewicz, S. J.
10.1101/2022.09.30.510406 — microbiology — Posted on 2023-02-28
165 SICKO: Systematic Imaging of Caenorhabtidis Killing Organisms
Espejo, L. S.; Freitas, S.; Silbar, V.; Chang, L.; Balsa, J.; Antenor, A.; Dang, H.; DeNicola, D.; Sutphin, G. L.
10.1101/2023.02.17.529009 — immunology — Posted on 2023-02-28
166 Signaling Node at TSC2 S1365 Potently Regulates T-Cell Differentiation and Improves Adoptive Cellular Cancer Therapy
Kass, D. A.; Powell, J. D.; Patel, C.; Dong, Y.; Dunkerly-Eyring, B. L.; Wen, J.; Ranek, M. J.; Bartle, L. M.; Henderson, D. B.; Sagert, J.
10.1101/2022.11.30.518569 — immunology — Posted on 2023-02-28
168 Repetitive Spreading Depolarization induces the activation of cell differentiation, synaptic plasticity and neuroprotective pathways.
Dell'Orco, M.; Weisend, J. E.; Perrone-Bizzozero, N. I.; Carlson, A. P.; Morton, R. A.; Linsenbardt, D. N.; Shuttleworth, C. W.
10.1101/2023.02.27.530317 — neuroscience — Posted on 2023-02-28
169 Modelling Instantaneous Firing Rate of DBS Target Neuronal Ensembles in Basal Ganglia and Thalamus
Tian, Y.; Murphy, M. J. H.; Steiner, L. A.; Kalia, S.; Hodaie, M.; Lozano, A.; Hutchison, W. D.; Popovic, M.; Milosevic, L.; Lankarany, M.
10.1101/2022.06.28.497834 — neuroscience — Posted on 2023-02-28
170 Preterm infants show an atypical processing of the mother's voice
Filippa, M.; Benis, D.; Adam-Darque, A.; Grandjean, D.; Huppi, P. S.
10.1101/2022.04.26.489394 — neuroscience — Posted on 2023-02-28
173 Cerebellar Granule Cells Develop Non-neuronal 3D Genome Architecture over the Lifespan
Tan, L.; Shi, J.; Moghadami, S.; Wright, C. P.; Parasar, B.; Seo, Y.; Vallejo, K.; Cobos, I.; Duncan, L.; Chen, R.; Deisseroth, K.
10.1101/2023.02.25.530020 — neuroscience — Posted on 2023-02-28
175 A Sweeter Future: Using protein language models for exploring sweeter brazzein homologs
Chua, B. N.; Guo, W. M.; Wong, H. T.; Ow, D. S.-W.; Ho, P. L.; Koh, W.; Koay, A.; Wong, F. T.
10.1101/2023.02.20.529172 — synthetic biology — Posted on 2023-02-28
176 Mammary Tissue-Derived Extracellular Matrix Hydrogels Reveal the Role of the Irradiated Microenvironment in Breast Cancer Recurrence
Zhu, T.; Alves, S. M.; Adamo, A.; Wen, X.; Corn, K. C.; Shostak, A.; Shaub, N. D.; Hacker, B. C.; D'Amore, A.; Bardhan, R.; Rafat, M.
10.1101/2022.05.16.492117 — cancer biology — Posted on 2023-02-28
177 Transcription elongation defects link oncogenic splicing factor mutations to targetable alterations in chromatin landscape
Boddu, P. C.; Gupta, A. K.; Roy, R.; De La Pena Avalos, B.; Olazabal Herrero, A.; Neuenkirchen, N.; Zimmer, J.; Chandhok, N. S.; King, D.; Nannya, Y.; Ogawa, S.; Lin, H.; Simon, M.; Dray, E.; Kupfer, G.; Verma, A. K.; Neugebauer, K. M.; Pillai, M. M.
10.1101/2023.02.25.530019 — cancer biology — Posted on 2023-02-28
178 A data-fusion approach to identifying developmental dyslexia from multi-omics datasets
Carrion, J. T.; Nandakumar, R.; Shi, X.; Gu, H.; Kim, Y.; Raskind, W. H.; Peter, B.; Dinu, V.
10.1101/2023.02.27.530280 — bioinformatics — Posted on 2023-02-28
181 At-home bacteria collection using CandyCollect, a lollipop-inspired device
Tu, W.-c.; McManamen, A. M.; Su, X.; Jeacopello, I.; Takezawa, M. G.; Hieber, D. L.; Hassan, G. W.; Lee, U. N.; Anana, E. V.; Locknane, M. P.; Stephenson, M. W.; Shinkawa, V. A. M.; Wald, E. R.; DeMuri, G. P.; Adams, K.; Berthier, E.; Thongpang, S.; Theberge, A. B.
10.1101/2023.01.14.524039 — biochemistry — Posted on 2023-02-28
182 DOCK3 regulates normal skeletal muscle regeneration and glucose metabolism
Samani, A.; Karuppasamy, M.; English, K. G.; Siler, C. A.; Wang, Y.; Widrick, J. J.; Alexander, M. S.
10.1101/2023.02.22.529576 — genetics — Posted on 2023-02-27
183 Opiate responses are controlled by interactions of Oprm1 and Fgf12 loci in rodents: Correspondence to human GWAS findings
Lemen, P. M.; Zuo, Y.; Hatoum, A. S.; Dickson, P. E.; Mittleman, G.; Agrawal, A.; Reiner, B. C.; Berrettini, W.; Ashbrook, D. G.; Gunturkun, H.; Mulligan, M. K.; Williams, R. W.; Telese, F.; Chen, H.
10.1101/2022.03.11.483993 — genetics — Posted on 2023-02-28
184 Using developmental rules to align microevolutionwith macroevolution
Machado, F. A.; Mongle, C. S.; Slater, G.; Penna, A.; Wisniewski, A.; Soffin, A.; Dutra, V.; Uyeda, J. C.
10.1101/2022.08.19.504140 — evolutionary biology — Posted on 2023-02-28
185 No evidence for associations between brood size, gut microbiome diversity and survival in great tit (Parus major) nestlings
Liukkonen, M.; Hukkanen, M.; Cossin-Sevrin, N.; Stier, A.; Vesterinen, E.; Grond, K.; Ruuskanen, S.
10.1101/2022.09.06.506880 — ecology — Posted on 2023-02-28
186 Single-cell analysis of CX3CR1+ cells reveal a pathogenic role for BIRC5+ myeloid proliferating cells driven by Staphylococcus aureus leukotoxins
Loredan, D. G.; Devlin, J. C.; Lacey, K. A.; Howard, N.; Chen, Z.; Zwack, E. E.; Lin, J.-D.; Ruggles, K. V.; Khanna, K. M.; Torres, V. J.; Loke, P.
10.1101/2023.02.27.529760 — immunology — Posted on 2023-02-27
188 Autophagy in maternal tissues contributes to Arabidopsis thaliana seed development.
Erlichman, O.; Weiss, S.; Abu-Arkia, M.; Khaner, M. A.; Soroka, Y.; Jasinska, W.; Rosental, L.; Brotman, Y.; Avin-Wittenberg, T.
10.1101/2023.02.27.530228 — plant biology — Posted on 2023-02-27
189 Genetic features and genomic targets of human KRAB-Zinc Finger Proteins
de Tribolet-Hardy, J.; Thorball, C. W.; Forey, R.; Planet, E.; Duc, J.; Khubieh, B.; Offner, S.; Fellay, J.; Imbeault, M.; Turelli, P.; Trono, D.
10.1101/2023.02.27.530095 — genomics — Posted on 2023-02-27
202 Genomic perspectives of SARS CoV-2 in liver disease patients with its clinical correlation: A single centre retrospective study
Bhugra, A.; Agarwal, R.; Gautam, P.; Suroliya, V.; Chhabra, R.; Pandey, A.; Garg, P.; Rao, P.; Babu, R.; Kumar, G.; SM, S.; Bihari, C.; Sarin, S. K.; Gupta, E.
10.1101/2023.02.26.530067 — microbiology — Posted on 2023-02-27
204 Drought Recovery Induced Immunity Confers Pathogen Resistance
Illouz-Eliaz, N.; Lande, K.; Yu, J.; Jow, B.; Swift, J.; Lee, T.; Nobori, T.; Castanon, R. G.; Nery, J. R.; Ecker, J. R.
10.1101/2023.02.27.530256 — plant biology — Posted on 2023-02-27
206 Adversarial and variational autoencoders improve metagenomic binning
Piera Lindez, P.; Johansen, J.; Sigurdsson, A. I.; Nissen, J. N.; Rasmussen, S.
10.1101/2023.02.27.527078 — bioinformatics — Posted on 2023-02-27
207 Nanoparticle targeting of mechanically modulated glycocalyx
Kohon, A.; Man, K.; Mathis, K.; Webb, J.; Yang, Y.; Meckes, B.
10.1101/2023.02.27.529887 — bioengineering — Posted on 2023-02-27
209 Uncovering the essential roles of human GCP 2 orthologs in Caenorhabditis elegans.
Panska, L.; Nedvedova, S.; Vacek, V.; Krivska, D.; Konecny, L.; Knop, F.; Kutil, Z.; Skultetyova, L.; Leontovyc, A.; Ulrychova, L.; Sakanari, J.; Asahina, M.; Barinka, C.; Macurkova, M.; Dvorak, J.
10.1101/2023.02.27.529682 — biochemistry — Posted on 2023-02-27
210 Sterically enhanced control of enzyme-assisted DNA assembly
Irving, O. J.; Matthews, L.; Coulthard, S.; Neely, R. K.; Grant, M. M.; Albrecht, T.
10.1101/2023.02.27.530245 — biochemistry — Posted on 2023-02-27
211 luxA gene from Enhygromyxa salina encodes a functional homodimeric luciferase
Yudenko, A.; Bazhenov, S. V.; Aleksenko, V. A.; Goncharov, I. M.; Semenov, O.; Remeeva, A.; Nazarenko, V. V.; Kuznetsova, E.; Fomin, V. V.; Konopleva, M. N.; Al Ebrahim, R.; Sluchanko, N. N.; Ryzhykau, Y.; Semenov, Y. S.; Kuklin, A.; Manukhov, I. V.; Gushchin, I.
10.1101/2023.02.27.530324 — biochemistry — Posted on 2023-02-27
212 An interchangeable prion-like domain is required for Ty1 retrotransposition
Beckwith, S. L.; Nomberg, E. J.; Newman, A. C.; Taylor, J. V.; Guerrero, R. C.; Garfinkel, D. J.
10.1101/2023.02.27.530227 — genetics — Posted on 2023-02-27
214 Salmonella Typhimurium effector SseI regulates host peroxisomal dynamics to acquire lysosomal cholesterol for better intracellular growth
Raj, D.; Nair, A. V.; Sharma, J.; Prakash, S.; Kaushik, A.; Basu, S.; Sahu, S.; Singh, S.; Bhosale, V.; Chandra, T.; Ghoshal, U. C.; Dasgupta, A.; Siddiqi, M. I.; Gupta, S. K.; Chakravortty, D.; Ammanathan, V.; LAHIRI, A.
10.1101/2023.02.27.530266 — cell biology — Posted on 2023-02-27
215 Phage T3 overcomes the BREX defence through SAM cleavage and inhibition of SAM synthesis
Andriianov, A.; Triguis, S.; Drobiazko, A.; Sierro, N.; Ivanov, N. V.; Selmer, M.; Severinov, K.; Isaev, A.
10.1101/2023.02.27.530186 — microbiology — Posted on 2023-02-27
216 Pathogenicity, strain properties and interspecies transmission capacity of pure recombinant prion protein assemblies
Rezaei, H.; Martin, D.; Herzog, L.; Reine, F.; Aron, N.; Igel, A.; Klute, H.; Youssafi, S.; Moog, J.-B.; Sibille, P.; Andreoletti, O.; Torrent, J.; Beringue, V.
10.1101/2023.02.27.530231 — microbiology — Posted on 2023-02-27
217 Kinematic markers of skill in first-person shooter video games
Warburton, M.; Campagnoli, C.; Mon-Williams, M.; Mushtaq, F.; Morehead, J. R.
10.1101/2023.02.27.530169 — neuroscience — Posted on 2023-02-27
221 Intra-prostatic tumour evolution, steps in metastatic spread and histogenomic associations revealed by integration of multi-region whole genome sequencing with histopathological features
Rao, S. R.; Verrill, C.; Cerundolo, L.; Alham, N. K.; Kaya, Z.; O'Hanlon, M.; Hayes, A.; Lambert, A.; James, M.; Tullis, I. D. C.; Niederer, J.; Lovell, S.; Omer, A.; Lopez, F.; Leslie, T.; Buffa, F. M.; Bryant, R. J.; Lamb, A. D.; Vojnovic, B.; Wedge, D. C.; Mills, I. G.; Woodcock, D. J.; Tomlinson, I. P. M.; Hamdy, F. C.
10.1101/2023.02.27.530113 — cancer biology — Posted on 2023-02-27
227 Multiscale networks in multiple sclerosis
Kennedy, K. E.; Kerlero de Rosbo, N.; Uccelli, A.; Cellerino, M.; Ivaldi, F.; Contini, P.; De Palma, R.; Harbo, H. H.; Berge, T.; Bos, S. D.; Hogestol, E. A.; Brune-Ingebretsen, S.; de Rodez Benavent, S.; Paul, F.; Brandt, A. U.; Bäcker-Koduah, P.; Behrens, J.; Kuchling, J.; Asseyer, S. E.; Scheel, M.; Chien, C.; Zimmermann, H.; Motamedi, S.; Kauer-Bonin, J.; Saez-Rodriguez, J.; Rinas, M.; Alexopoulos, L.; Andorra, M.; Llufriu, S.; Saiz, A.; Blanco, Y.; Martinez-Heras, E.; Solana, E.; Pulido-Valdeolivas, I.; Martinez-Lapiscina, E. H.; Garcia-Ojalvo, J.; Villoslada, P.
10.1101/2023.02.26.530153 — systems biology — Posted on 2023-02-27
228 The human pathome shows sex specific aging patterns post-development
Ben Ezra, M.; Garbrecht, J. B.; Rasmussen, N.; Heckenbach, I.; Petr, M. A.; Bakula, D. J.; Mortensen, L. H.; Scheibye-Knudsen, M.
10.1101/2023.02.27.530179 — physiology — Posted on 2023-02-27
231 Automated quantification of lipophagy in Saccharomyces cerevisiae from fluorescence and cryo-soft X-ray microscopy data using deep learning
Egebjerg, J.; Szomek, M.; Thaysen, K.; Dupont Juhl, A.; Pratsch, C.; Werner, S.; Schneider, G.; Rottger, R.; Wustner, D.
10.1101/2023.02.27.530171 — bioinformatics — Posted on 2023-02-27
234 Plants cultivated for ecosystem restoration can evolve towards a domestication syndrome
Conrady, M.; Lampei, C.; Bossdorf, O.; Hoelzel, N.; Michalski, S.; Durka, W.; Bucharova, A.
10.1101/2023.02.27.530164 — ecology — Posted on 2023-02-27
236 Therapeutic and vaccine-induced cross-reactive antibodies with effector function against emerging Omicron variants
Addetia, A.; Piccoli, L.; Case, J. B.; Park, Y.-J.; Beltramello, M.; Guarino, B.; Dang, H.; Pinto, D.; Scheaffer, S.; Sprouse, K.; Bassi, J.; Silacci-Fregni, C.; Muoio, F.; Dini, M.; Vincenzetti, L.; Acosta, R.; Johnson, D.; Subramanian, S.; Saliba, C.; Giurdanella, M.; Lombardo, G.; Leoni, G.; Culap, K.; McAlister, C.; Rajesh, A.; Dellota, E.; Zhou, J.; Farhat, N.; Bohan, D.; Noack, J.; Lempp, F. A.; Cameroni, E.; Whitener, B.; Giannini, O.; Ceschi, A.; Ferrari, P.; Franzetti-Pellanda, A.; Biggiogero, M.; Garzoni, C.; Zappi, S.; Bernasconi, L.; Kim, M. J.; Schnell, G.; Czudnochowski, N.; Fran
10.1101/2023.01.17.523798 — immunology — Posted on 2023-02-27
238 The classic psychedelic DOI induces a persistent desynchronized state in medial prefrontal cortex
Olson, R.; Bartlett, L.; Sonneborn, A.; Bretton-Granatoor, Z.; Firdous, A.; Harris, A.; Abbas, A.
10.1101/2023.02.26.529963 — neuroscience — Posted on 2023-02-27
240 Anesthesia suppresses gastric myoelectric power in the ferret
Tomaselli, L.; Sciullo, M.; Fulton, S.; Yates, B. J.; Fisher, L. E.; Ventura, V.; Horn, C. C.
10.1101/2023.02.23.529745 — neuroscience — Posted on 2023-02-27
241 Dissociable contributions of the amygdala and ventral hippocampus to stress-induced changes in defensive behavior
Pennington, Z. T.; LaBanca, A. R.; Sompolpong, P.; Christenson Wick, Z.; Feng, Y.; Shuman, T.; Cai, D. J.
10.1101/2023.02.27.530077 — neuroscience — Posted on 2023-02-27
242 Dopamine dysregulation in Parkinson's disease flattens the pleasurable urge to move to musical rhythms
Pando-Naude, V.; Matthews, T. E.; Hojlund, A.; Jakobsen, S.; Ostergaard, K.; Johnsen, E.; Garza-Villarreal, E. A.; Witek, M.; Penhune, V. B.; Vuust, P.
10.1101/2023.02.27.530174 — neuroscience — Posted on 2023-02-27
245 HAPPY: A deep learning pipeline for mapping cell-to-tissue graphs across placenta histology whole slide images
Vanea, C.; Dzigurski, J.; Rukins, V.; Dodi, O.; Siigur, S.; Salumae, L.; Meir, K.; Parks, W. T.; Hochner-Celnikier, D.; Fraser, A.; Hochner, H.; Laisk, T.; Ernst, L. M.; Lindgren, C. M.; Nellaker, C.
10.1101/2022.11.21.517353 — bioinformatics — Posted on 2023-02-27
246 Repurposing of Anti-infectives for the Management of Onchocerciasis using Machine Learning and Protein Docking Studies
Tetteh, C. N. O.-K.; Ampomah, B.; Oppong, M. B.; Lartey, M.; Donkor, P. O.; Opuni, K. F.-M.; Adutwum, L. A.
10.1101/2023.02.26.530155 — bioinformatics — Posted on 2023-02-27
248 Engineered ketocarotenoid biosynthesis in the polyextremophilic red microalga Cyanidioschyzon merolae 10D
Seger, M.; Mammadova, F.; Villegas-Valencia, M.; Bastos de Freitas, B.; Cheng, C.; Isachsen, I.; Hemstreet, H.; Abualsaud, F.; Boring, M.; Lammers, P. J.; Lauersen, K. J.
10.1101/2023.02.27.530181 — bioengineering — Posted on 2023-02-27
253 Comparative proximity biotinylation implicates RAB18 in sterol mobilization and biosynthesis
Kiss, R. S.; Chicoine, J.; Khalil, Y.; Sladek, R.; Chen, H.; Pisaturo, A.; Martin, C.; Dale, J. D.; Brudenell, T. A.; Kamath, A.; Paci, E.; Kerksiek, A.; Lütjohann, D.; Clayton, P.; Wills, J. C.; von Kriegsheim, A.; Nilsson, T.; Sheridan, E.; Handley, M. T.
10.1101/871517 — cell biology — Posted on 2023-02-27
255 Whole genome sequencing of Borrelia burgdorferi isolates reveals linked clusters of plasmid-borne accessory genome elements associated with virulence.
Lemieux, J. E.; Huang, W.; Hill, N.; Cerar, T.; Freimark, L.; Hernandez, S.; Luban, M.; Maraspin, V.; Bogovic, P.; Ogrinc, K.; Lapierre, P.; Lasek-Nesselquist, E.; Singh, N.; Iyer, R.; Liveris, D.; Reed, K. D.; Leong, J. M.; Branda, J. A.; Steere, A. C.; Wormser, G. P.; Strle, F.; Sabeti, P. C.; Schwartz, I.; Strle, K.
10.1101/2023.02.26.530159 — microbiology — Posted on 2023-02-27
256 Active maintenance of CD8+ T cell naivety through regulation of global genome architecture
Russ, B. E.; Tsyganov, K.; Quon, S.; Yu, B.; Li, J.; Lee, J. K.; Olshansky, M.; He, Z.; Harrison, P. F.; Barugahare, A.; See, M.; Nuessing, S.; Morey, A. E.; Udupa, V. A.; Bennett, T. J.; Kallies, A.; Murre, C.; Collas, P.; Powell, D.; Goldrath, A. W.; Turner, S. J.
10.1101/2023.02.26.530139 — immunology — Posted on 2023-02-27
257 FOXP3+ regulatory T cells use heparanase to access IL-2 bound to ECM in inflamed tissues
Martinez, H. A.; Koliesnik, I.; Kaber, G.; Nagy, N.; Barlow, G.; Falk, B. A.; Reid, J. K.; Medina, C. O.; Hargil, A.; Vlodavsky, I.; Li, J.-p.; Perez-Cruz, M.; Tang, S.-W.; Meyer, E. H.; Wrenshall, L. E.; Lord, J. D.; Garcia, K. C.; Palmer, T. D.; Steinman, L.; Nepom, G. T.; Wight, T. N.; Bollyky, P. L.; Kuipers, H. F.
10.1101/2023.02.26.529772 — immunology — Posted on 2023-02-27
260 An associative transcriptomics study on rice bean (Vigna umbellata) provides new insights into genetic basis and candidate genes governing flowering, maturity and seed weight
Sahu, T. K.; Verma, S. K.; Gayacharan, ; Singh, N. P.; Joshi, D. C.; Wankhede, D. P.; Singh, M.; Bhardwaj, R.; Parida, S. K.; Chattopadhyay, D.; Singh, G. P.; Singh, A. K.
10.1101/2023.02.25.530014 — bioinformatics — Posted on 2023-02-27
261 Bactabolize: A tool for high-throughput generation of bacterial strain-specific metabolic models
Vezina, B.; Watts, S. C.; Hawkey, J.; Cooper, H. B.; Judd, L. M.; Jenney, A.; Monk, J. M.; Holt, K. E.; Wyres, K. L.
10.1101/2023.02.26.530115 — bioinformatics — Posted on 2023-02-27
262 Clonal phylogenies inferred from bulk, single cell, and spatial transcriptomic analysis of cancer
Erickson, A.; Figiel, S.; Rajakumar, T.; Rao, S.; Yin, W.; Doultsinos, D.; Magnussen, A.; Singh, R.; Poulose, N.; Bryant, R. J.; Cussenot, O.; Hamdy, F. C.; Woodcock, D.; Mills, I. G.; Lamb, A. D.
10.1101/2023.02.26.530145 — bioinformatics — Posted on 2023-02-27
266 Metagenome diversity illuminates origins of pathogen effectors
Verhoeve, V. I.; Lehman, S. S.; Driscoll, T. P.; Beckmann, J. F.; Gillespie, J. J.
10.1101/2023.02.26.530123 — microbiology — Posted on 2023-02-27
267 The vaginal microbiota of pregnant women varies with gestational age, maternal age, and parity
Romero, R.; Theis, K. R.; Gomez-Lopez, N.; Winters, A. D.; Panzer, J.; Lin, H.; Galaz, J.; Greenberg, J. M.; Shaffer, Z. D.; Kracht, D. J.; Chaiworapongsa, T.; Jung, E.; Gotsch, F.; Ravel, J.; Peddada, S. D.; Tarca, A. L.
10.1101/2023.02.26.530121 — microbiology — Posted on 2023-02-27
268 Mode-based morphometry: A multiscale approach to mapping human neuroanatomy
Cao, T.; Pang, J. C.; Segal, A.; Chen, Y.-C.; Aquino, K. M.; Breakspear, M.; Fornito, A.
10.1101/2023.02.26.529328 — neuroscience — Posted on 2023-02-27
271 Expression of cell-wall related genes is highly variable and correlates with sepal morphology
Hartasanchez, D. A.; Kiss, A. K.; Battu, V.; Soraru, C.; Delgado Vaquera, A.; Massinon, F.; Braso-Vives, M.; Mollier, C.; Martin-Magnette, M.-L.; Boudaoud, A.; Moneger, F.
10.1101/2022.04.26.489498 — plant biology — Posted on 2023-02-27
272 A layer cake model for plant and metazoan chromatin
Mozziconacci, J.; Carron, L.; Concia, L.; Grob, S.; Barneche, F.; Carbone, A.
10.1101/2023.02.24.529851 — genomics — Posted on 2023-02-27
274 A cleaved METTL3 potentiates the METTL3-WTAP interaction and breast cancer progression
Zhang, J.; Yan, C.; Xiong, J.; Zhou, Z.; Li, Q.; Gao, C.; Zhang, M.; Yu, L.; Li, J.; Hu, M.-M.; Zhang, C.-S.; Cai, C.; Zhang, H.
10.1101/2023.02.17.528944 — cell biology — Posted on 2023-02-27
276 Exploring the phytobeneficial and biocontrol capacities of endophytic bacteria isolated from hybrid vanilla pods
Lalanne-Tisne, G.; Barral, B.; Taibi, A.; Coulibaly, Z. K.; Burguet, P.; Rasoarahona, F.; Quinton, L.; Meile, J.-C.; Boubakri, H.; Kodja, H.
10.1101/2023.02.24.529991 — microbiology — Posted on 2023-02-27
277 AedG, a new weapon in Acinetobacters fight against antimicrobials
Naidu, V. N.; Shah, B.; Maher, C.; Paulsen, I. T.; Hassan, K. A.
10.1101/2023.01.03.522653 — microbiology — Posted on 2023-02-27
278 The immune regulation and epidemiological consequences of immune priming in Drosophila
Prakash, A.; Fenner, F.; Shit, B.; Salminen, T. S.; Monteith, K. M.; Khan, I.; Vale, P. F.
10.1101/2023.02.22.529244 — immunology — Posted on 2023-02-27
279 Mass spectrometric profiling of HLA-B44 peptidomes provides evidence for tapasin-mediated tryptophan editing
KAUR, A.; SURNILLA, A.; ZAITOUNA, A. J.; VENKATESHA, B.; MUMPHREY, M. B.; GRIGOROVA, I. L.; CIESLIK, M.; CARRINGTON, M.; NESVIZHSKII, A. I.; Raghavan, M.
10.1101/2023.02.26.530125 — immunology — Posted on 2023-02-27
281 BERBERINE BRIDGE ENZYME-LIKE OXIDASES OF CELLODEXTRINS AND MIXED-LINKED β-GLUCANS CONTROL SEED COAT FORMATION
Costantini, S.; Benedetti, M.; Pontiggia, D.; Giovannoni, M.; Cervone, F.; Mattei, B.; De Lorenzo, G.
10.1101/2023.02.24.529966 — plant biology — Posted on 2023-02-27
282 Evaluation of non-modified wireframe DNA origami for acute toxicity and biodistribution in mice
Wamhoff, E.-C.; Knappe, G. A.; Burds, A. A.; Du, R. R.; Neun, B.; Difilippantonio, S.; Sanders, C.; Edmondson, E.; Matta, J. L.; Dobrovolskaia, M.; Bathe, M.
10.1101/2023.02.25.530026 — pharmacology and toxicology — Posted on 2023-02-27
286 Convolutional-recurrent neural networks approximate diffusion tractography from T1-weighted MRI and associated anatomical context
Cai, L. Y.; Lee, H. H.; Newlin, N. R.; Kerley, C. I.; Kanakaraj, P.; Yang, Q.; Johnson, G. W.; Moyer, D.; Schilling, K. G.; Rheault, F.; Landman, B. A.
10.1101/2023.02.25.530046 — bioengineering — Posted on 2023-02-27
287 Pretraining strategies for effective promoter-driven gene expression prediction
Reddy, A. J.; Herschl, M. H.; Kolli, S.; Lu, A. X.; Geng, X.; Kumar, A.; Hsu, P. D.; Levine, S.; Ioannidis, N. M.
10.1101/2023.02.24.529941 — genomics — Posted on 2023-02-27
289 Wolbachia genomics reveals a potential for a nutrition-based symbiosis in blood-sucking Triatomine bugs
Filee, J.; Agesilas-Lequeux, K.; Lacquehay, L.; Berenger, J. M.; Dupont, L.; Mendonca, V.; Aristeu da Rosa, J.; Harry, M.
10.1101/2022.09.06.506778 — evolutionary biology — Posted on 2023-02-27
290 100 years of anthropogenic impact causes changes in freshwater functional biodiversity
Eastwood, N.; Zhou, J.; Derelle, R.; Abdallah, M. A.-E.; Stubbings, W. A.; Jia, Y.; Crawford, S. E.; Davidson, T. A.; Colbourne, J. K.; Creer, S.; Bik, H.; Hollert, H.; Orsini, L.
10.1101/2023.02.26.530075 — ecology — Posted on 2023-02-27
292 Mutual regulation of transcriptomes between pneumocytes and fibroblasts mediates alveolar regeneration
Yao, Y.; Miethe, S.; Kattler, K.; Walter, J.; Schneider-Daum, N.; Herr, C.; Garn, H.; Ritzmann, F.; Bals, R.; Beisswenger, C.
10.1101/2023.02.27.530149 — cell biology — Posted on 2023-02-27
293 Airway secretory cell-derived p63+ progenitors contribute to alveolar regeneration after sterile lung injury
Lv, Z.; Liu, Z.; Liu, K.; Pu, W.; Li, Y.; Zhao, H.; Xi, Y.; Vaughan, A.; Gillich, A.; Zhou, B.
10.1101/2023.02.27.530122 — cell biology — Posted on 2023-02-27
294 Specific subcellular localization drives the different functions of CDC42 isoforms during migration
Ravichandran, Y.; Hanisch, J.; Murray, K.; Roca, V.; Dingli, F.; Loew, D.; Sabatet, V.; Boeda, B.; Etienne-Manneville, S.
10.1101/2023.02.27.528078 — cell biology — Posted on 2023-02-27
295 Molecular mechanisms of heavy metal adaptation of an extremophilic red alga Cyanidioschyzon merolae
Marchetto, F.; Santaeufemia, S.; Lebiedzinska-Arciszewska, M.; Sliwinska, M. A.; Pich, M.; Kurek, E.; Naziebło, A.; Strawski, M.; Solymosi, D.; Szklarczyk, M.; Bulska, E.; Szymanski, J.; Wierzbicka, M.; Allahverdiyeva, Y.; Wieckowski, M. R.; Kargul, J. M.
10.1101/2023.02.24.529964 — cell biology — Posted on 2023-02-27
297 Secretory IgM (sIgM) is an ancient master regulator of microbiota homeostasis and metabolism
Ding, Y.; Fernandez-Montero, A.; Mani, A.; Casadei, E.; Shibasaki, Y.; Takizawa, F.; Miyazawa, R.; Salinas, I.; Sunyer, J. O.
10.1101/2023.02.26.530119 — immunology — Posted on 2023-02-27
305 Mitochondrial Calcium Uptake Declines during Aging and is Directly Activated by Oleuropein to Boost Energy Metabolism and Skeletal Muscle Performance
Gherardi, G.; Weiser, A.; Bermont, F.; Migliavacca, E.; Brinon, B.; Jacot, G. E.; Hermant, A.; Sturlese, M.; Nogara, L.; Barron, D.; Blaauw, B.; Moro, S.; Rizzuto, R.; Feige, J. N.; Mammucari, C.; DeMarchi, U.
10.1101/2023.02.24.529830 — physiology — Posted on 2023-02-27
307 The IRE1α-endonuclease regulates PD-1 expression through a novel XBP1/miRNA-34a axis within Natural Killer cells
Bednarska, K.; Thillaiyampalam, G.; Mujaj, S.; Nourse, J.; Gunawardana, J.; Sabdia, M. B.; Cui, Q.; de Long, L. M.; Vari, F.; Gandhi, M. K.; Cristino, A. S.
10.1101/2023.02.26.530063 — cancer biology — Posted on 2023-02-27
308 Screening in serum-derived medium reveals differential response to compounds targeting metabolism
Abbott, K. L.; Ali, A.; Casalena, D.; Do, B. T.; Ferreira, R.; Cheah, J. H.; Soule, C. K.; Deik, A.; Kunchok, T.; Schmidt, D. R.; Renner, S.; Honeder, S. E.; Wu, M.; Chan, S. H.; Tseyang, T.; Greaves, D.; Hsu, P. P.; Ng, C. W.; Zhang, C. J.; Farsidjani, A.; Gramatikov, I. M. T.; Matheson, N. J.; Lewis, C. A.; Clish, C. B.; Rees, M. G.; Roth, J. A.; Griner, L. M.; Muir, A.; Auld, D. S.; Vander Heiden, M. G.
10.1101/2023.02.25.529972 — cancer biology — Posted on 2023-02-27
317 Multiscale Multimodal Characterization and Simulation of Structural Alterations in Failed Bioprosthetic Heart Valves
Tsolaki, E.; Corso, P.; Zboray, R.; Avaro, J.; Appel, C.; Liebi, M.; Bertazzo, S.; Heinisch, P. P.; Carrel, T.; Obrist, D.; Herrmann, I. K.
10.1101/2023.02.26.529530 — bioengineering — Posted on 2023-02-27
318 Zero-shot learning enables instant denoising and super-resolution in optical fluorescence microscopy
Qiao, C.; Zeng, Y.; Meng, Q.; Chen, X.; Chen, H.; Jiang, T.; Wei, R.; Guo, J.; Fu, W.; Lu, H.; Li, D.; wang, Y.; Qiao, H.; Wu, J.; Li, D.; Dai, Q.
10.1101/2023.02.24.529803 — bioengineering — Posted on 2023-02-27
319 A novel antifolate suppresses growth of FPGS-deficient cells and overcomes methotrexate resistance
van der Krift, F.; Zijlmans, D. W.; Shukla, R.; Javed, A.; Koukos, P. I.; Schwarz, L. L. E.; Timmermans-Sprang, E. P. M.; Maas, P. E. M.; Gahtory, D.; van den Nieuwboer, M.; Mol, J. A.; Strous, G. J.; Bonvin, A. M. J. J.; Veldhuizen, E. J. A.; van der Stelt, M.; Weingarth, M.; Vermeulen, M.; Klumperman, J.; Maurice, M. M.
10.1101/2023.02.26.530079 — biochemistry — Posted on 2023-02-27
322 Conservation implications of elucidating the Korean wolf taxonomic ambiguity through whole-genome sequencing
Hernandez Alonso, G.; Ramos-Madrigal, J.; Sun, X.; Hjorth Scharff-Olsen, C.; Sinding, M.-H. S.; Martins, N. F.; Ciucani, M. M.; Mak, S. S. T.; Lanigan, L. T.; Clausen, C. C.; Bhak, J.; Jeon, S.; Kim, C.; Yeon Eo, K.; Cho, S.-H.; Bazartseren, B.; Gantulga, G.; Unudbayasgalan, Z.; Kosintsev, P. A.; Stenoien, H. K.; Gilbert, M. T. P.; Gopalakrishnan, S.
10.1101/2023.02.24.529912 — evolutionary biology — Posted on 2023-02-27
326 A unifying principle for global greenness patterns and trends
Cai, W.; Zhu, Z.; Harrison, S. P.; Ryu, Y.; Wang, H.; Zhou, B.; Prentice, I. C.
10.1101/2023.02.25.529932 — ecology — Posted on 2023-02-27
327 Coexistence in Periodic Environments
Scott, A. M.; Bieg, C.; McMeans, B. M.; McCann, K.
10.1101/2023.02.24.529749 — ecology — Posted on 2023-02-27
329 Boosting the toolbox for live imaging of translation
Bellec, M.; Chen, R.; Dhayni, J.; Favard, C.; Trullo, A.; Lenden-Hasse, H.; Lehmann, R.; Bertrand, E.; Lagha, M.; Dufourt, J.
10.1101/2023.02.25.529998 — developmental biology — Posted on 2023-02-27
332 Incorporation of TRDV segments into TCR alpha chains
Volkmar, M.; Fakhr, E.; Zens, S.; Offringa, R.; Bury, A.; Gordon, J.; Huduti, E.; Woelfel, T.; Woelfel, C.
10.1101/2023.02.26.530072 — immunology — Posted on 2023-02-27
334 Lifespan Changes in Brain Structure and Cognitive Performance Associated with Normal Aging in Mice
Clifford, K. P.; Miles, A.; Prevot, T. D.; Misquitta, K. A.; Ellegood, J.; Lerch, J. P.; Sibille, E.; Nikolova, Y. S.; Banasr, M.
10.1101/2023.02.24.529940 — neuroscience — Posted on 2023-02-27
335 Architectural experience influences the processing of others' body expressions
Presti, P.; Galasso, G. M.; Ruzzon, D.; Avanzini, P.; Caruana, F.; Rizzolatti, G.; Vecchiato, G.
10.1101/2023.02.24.529649 — neuroscience — Posted on 2023-02-27
342 Leptomeningeal collaterals regulate reperfusion in ischemic stroke
Binder, N.; El Amki, M.; Glueck, C.; Middleham, W.; Reuss, A. M.; Bertolo, A.; Thurner, P.; Deffieux, T.; Handelsmann, H.-L.; Baumgartner, P.; Orset, C.; Bethge, P.; Kulcsar, Z.; Aguzzi, A.; Tanter, M.; Vivien, D.; Wyss, M. T.; Luft, A.; Weller, M.; Weber, B.; Wegener, S.
10.1101/2023.02.25.529915 — neuroscience — Posted on 2023-02-27
343 Activity-dependent induction of astrocytic Slc22a3 regulates sensory processing through histone serotonylation
Sardar, D.; Cheng, Y.-T.; Woo, J.; Choi, D.-J.; Lee, Z.-F.; Kwon, W.; Chen, H.-C.; Lozzi, B.; Cervantes, A.; Rajendran, K.; Huang, T.-W.; Jain, A.; Arenkiel, B.; Maze, I.; Deneen, B.
10.1101/2023.02.24.529904 — neuroscience — Posted on 2023-02-27
344 How Healthy Older Adults Enact Lateral Maneuvers While Walking
Desmet, D. M.; Kazanski, M. E.; Cusumano, J. P.; Dingwell, J. B.
10.1101/2023.02.24.529927 — neuroscience — Posted on 2023-02-27
346 Idioblasts accumulating anticancer alkaloids in Catharanthus roseus leaves are a unique cell type
Guedes, J. G.; Ribeiro, R.; Carqueijeiro, I.; Guimaraes, A. L.; Bispo, C.; Archer, J.; Azevedo, H.; Fonseca, N. A.; Sottomayor, M.
10.1101/2023.02.24.529939 — plant biology — Posted on 2023-02-27
349 Piscichuviral encephalitis in marine and freshwater chelonians: first evidence of jingchuviral disease
Laovechprasit, W.; Young, K.; Stacy, B. A.; Tillis, S. B.; Ossiboff, R. J.; Vann, J. A.; Subramaniam, K.; Agnew, D.; Zhang, J.; Whitaker, S.; Walker, A.; Orgill, A. M.; Howell, L. N.; Shaver, D. J.; Stanton, J. B.
10.1101/2023.02.24.528524 — pathology — Posted on 2023-02-27
350 The Dietary Supplement Taurine Suppresses Ovarian Cancer Growth
Centeno, D.; Farsinejad, S.; Kochetkova, E.; Volpari, T.; Klupczynska - Gabryszak, A.; Kung, D.; Polotaye, T.; Hyde, E.; Pavlovic, T.; Alshehri, S.; Sullivan, W.; Plewa, S.; Monsma, F. J.; Matysiak, J.; Zaborowski, M.; DiFeo, A.; Andres-Martin, L.; Norberg, E.; Iwanicki, M.
10.1101/2023.02.24.529893 — cancer biology — Posted on 2023-02-27
351 Acquired epithelial WNT secretion drives niche independence of developing gastric cancer
Teriyapirom, I.; Kim, J.; Lee, H.; Merker, S. R.; Andersson-Rolf, A.; Jahn, S. R.; Ada, A.-M.; Kim, S.-M.; Lim, J. Y.; Schmaeche, T.; Wetterling, N.; Stegert, S.; Park, J.-Y.; Cheong, J.-H.; Kim, H.; Stange, D. E.; Koo, B.-K.
10.1101/2023.02.24.529854 — cancer biology — Posted on 2023-02-27
353 A luminal intermediate cell state maintains long-term prostate homeostasis and contributes to tumorigenesis
Luo, F.; Tshering, L. F.; Tutuska, K.; Szenk, M.; Rubel, D.; Rail, J. G.; Russ, S.; Liu, J.; Nemajerova, A.; Balazsi, G.; Talos, F.
10.1101/2023.02.24.529762 — cancer biology — Posted on 2023-02-27
360 PIFiA: Self-supervised Approach for Protein Functional Annotation from Single-Cell Imaging Data
Razdaibiedina, A.; Brechalov, A. V.; Friesen, H.; Mattiazzi Usaj, M.; Masinas, M. P. D.; Garadi Suresh, H.; Wang, K.; Boone, C.; Ba, J.; Andrews, B. J.
10.1101/2023.02.24.529975 — bioinformatics — Posted on 2023-02-27
363 Traumatic brain injury-induced fear generalization in mice involves hippocampal memory trace dysfunction and is alleviated by (R,S)-ketamine
McGowan, J. C.; Ladner, L. R.; Shubeck, C. X.; Tapia, J.; LaGamma, C. T.; Anqueira-Gonzalez, A.; DeFrancesco, A.; Chen, B. K.; Hunsberger, H. C.; Sydnor, E. J.; Logan, R. W.; Yu, T.-S.; Kernie, S. G.; Denny, C. A.
10.1101/2023.02.24.529876 — animal behavior and cognition — Posted on 2023-02-27
365 Why Do Hybrids Turn Down Sex?
Fyon, F.; Berbel-Filho, W. M.; Schlupp, I.; Wild, G.; Ubeda, F.
10.1101/2023.02.24.529842 — evolutionary biology — Posted on 2023-02-27
368 Shared inflammatory glial cell signature after brain injury, revealed by spatial, temporal and cell-type-specific profiling of the murine cerebral cortex
Koupourtidou, C.; Schwarz, V.; Aliee, H.; Frerich, S.; Fischer-Sternjak, J.; Bocchi, R.; Simon-Ebert, T.; Dichgans, M.; Goetz, M.; Theis, F. J.; Ninkovic, J.
10.1101/2023.02.24.529840 — neuroscience — Posted on 2023-02-27
369 Dilated Virchow-Robin Spaces are a Marker for Arterial Disease in Multiple Sclerosis
Ineichen, B. V.; Cananau, C.; Platten, M.; Ouellette, R.; Moridi, T.; Frauenknecht, K. B. M.; Okar, S. V.; Kulcsar, Z.; Kockum, I.; Piehl, F.; Reich, D. S.; Granberg, T.
10.1101/2023.02.24.529871 — neuroscience — Posted on 2023-02-27
370 Microlenses fabricated by two-photon laser polymerisation for cell imaging with non-linear excitation microscopy
Marini, M.; Nardini, A.; Martinez Vazquez, R.; Conci, C.; Bouzin, M.; Collini, M.; Osellame, R.; Cerullo, G.; Kariman, B. S.; Farsari, M.; Kabouraki, E.; Raimondi, M. T.; Chirico, G.
10.1101/2022.11.17.516871 — bioengineering — Posted on 2023-02-27
372 Colour polymorphism associated with a gene duplication in male wood tiger moths
Brien, M. N.; Orteu, A.; Yen, E. C.; Galarza, J. A.; Kirvesoja, J.; Pakkanen, H.; Wakamatsu, K.; Jiggins, C. D.; Mappes, J.
10.1101/2022.04.29.490025 — evolutionary biology — Posted on 2023-02-27
373 Uremic toxin indoxyl sulfate induces trained immunity via the AhR-dependent arachidonic acid pathway in ESRD
Kim, H. Y.; Kim, D. H.; Lee, S. J.; Kang, Y. J.; Kim, G.; Koh, H. B.; Ko, Y. E.; Shin, H. M.; Lee, H.; Yoo, T.-H.; Lee, W.-W.
10.1101/2022.08.08.503143 — immunology — Posted on 2023-02-27
376 Acetylcholine engages distinct amygdala microcircuits to gate internal theta rhythm
Bratsch-Prince, J. X.; Warren, J. W.; Jones, G. C.; McDonald, A. J.; Mott, D. D.
10.1101/2023.02.26.530135 — neuroscience — Posted on 2023-02-27
380 Mobile brain imaging in butoh dancers: from rehearsals to public performance
Theofanopoulou, C.; Paez, S.; Huber, D.; Todd, E.; Ramirez-Moreno, M. A.; Khaleghian, B.; Sanchez, A. M.; Gand, V.; Contreras-Vidal, J. L.
10.1101/2023.02.26.530087 — neuroscience — Posted on 2023-02-26
385 Human immune phenotyping reveals accelerated aging in type 1 diabetes
Shapiro, M. R.; Dong, X.; Perry, D.; McNichols, J. M.; Thirawatananond, P.; Posgai, A. L.; Peters, L.; Motwani, K.; Musca, R.; Muir, A.; Concannon, P.; Jacobsen, L.; Mathews, C. E.; Wasserfall, C. H.; Haller, M. J.; Schatz, D. A.; Atkinson, M. A.; Brusko, M. A.; Bacher, R.; Brusko, T. M.
10.1101/2023.02.24.529902 — immunology — Posted on 2023-02-26
387 Sub-second fluctuations in extracellular dopamine encode reward and punishment prediction errors in humans
Sands, P.; Jiang, A.; Liebenow, B.; DiMarco, E.; Laxton, A.; Tatter, S.; Montague, R.; Kishida, K.
10.1101/2023.02.24.529709 — neuroscience — Posted on 2023-02-26
393 Deep Coverage and Quantification of the Bone Proteome Provides Enhanced Opportunities for New Discoveries in Skeletal Biology and Disease
Rose, J. P.; Schurman, C. A.; King, C. D.; Bons, J.; Burton, J. B.; Patel, S. K.; O'Broin, A.; Alliston, T.; Schilling, B.
10.1101/2022.11.20.517228 — biochemistry — Posted on 2023-02-26
394 A Golden Standard for Transcription Factor-Gene Regulatory Interactions in Escherichia coli K-12: How reliable are they based on the methods supporting them?
Lara, P.; Gama-Castro, S.; Salgado, H.; Rioualen, C.; Muniz- Rascado, L. J.; Garcia-Sotelo, J. S.; Tierrafria, V. H.; Collado-Vides, J.
10.1101/2023.02.25.530038 — genomics — Posted on 2023-02-26
395 Balancing selection at a wing pattern locus is associated with major shifts in genome-wide patterns of diversity and gene flow in a butterfly
Rodriguez de Cara, M. A.; Jay, P.; Rougemont, Q.; Chouteau, M.; Whibley, A.; Huber, B.; Piron-Prunier, F.; Ramos, R. R.; Freitas, A. V. L.; Salazar, C.; Silva-Brandao, K. L.; Torres, T. T.; Joron, M.
10.1101/2021.09.29.462348 — evolutionary biology — Posted on 2023-02-26
396 Diet influences resource allocation in chemical defence but not melanin synthesis in an aposematic moth
Ottocento, C.; Rojas, B.; Burdfield-Steel, E.; Furlanetto, M.; Nokelainen, O.; Winters, S.; Mappes, J.
10.1101/2023.02.24.529866 — ecology — Posted on 2023-02-26
397 Development of Cell Permeable NanoBRET Probes for the Measurement of PLK1 Target Engagement in Live Cells
Yang, X.; Smith, J. L.; Beck, M. T.; Wilkinson, J. M.; Michaud, A.; Vasta, J. D.; Robers, M. B.; Willson, T. M.
10.1101/2023.02.25.529946 — cell biology — Posted on 2023-02-26
398 Class IIa HDACs inhibit cell death pathways and protect muscle integrity in response to lipotoxicity
Martin, S. D.; Connor, T.; Sanigorski, A.; McEwen, K. A.; Henstridge, D. C.; Nijagal, B.; De Souza, D. P.; Tull, D.; Meikle, P.; Kowalski, G. M.; Bruce, C.; Gregorevic, P.; Febbraio, M.; Collier, F.; Walder, K. R.; McGee, S.
10.1101/2022.10.17.512492 — cell biology — Posted on 2023-02-26
399 Thiolutin is a direct inhibitor of RNA Polymerase II
Qiu, C.; Malik, I.; Arora, P.; Laperuta, A. J.; Pavlovic, E. M.; Ugochukwu, S.; Naik, M. T.; Kaplan, C. D.
10.1101/2021.05.05.442806 — molecular biology — Posted on 2023-02-26
400 Excessive apoptosis of naïve T cells resulting hyperactivation as a cause of mammalian aging
Wang, L.; Zhang, X.; Zhang, H.; Lu, K.; Li, M.; Li, X.; Ouyang, J.; Zhao, X.; Wu, X.; Wu, X.; Liu, J.; Xing, M.; Liu, H.; Zhang, Y.; Tan, Y.; Li, F.; Deng, J.; Zhang, X.; Li, J.; Zhao, Y.; Wang, X.; Luo, Y.; Zhou, B.; Zhang, H.
10.1101/2023.02.24.529806 — immunology — Posted on 2023-02-26
401 Alternative splicing of its 5' untranslated region controls CD20 mRNA translation and enables resistance to CD20-directed immunotherapies
Ang, Z.; Hayer, K. E.; Torres Diz, M.; Schmidt, C.; Zheng, S.; Xu, F.; Falkenstein, C. D.; Loftus, J. P.; Yang, S. Y.; Asnani, M.; Pillai, V.; Chong, E.; Li, M. M.; Tasian, S. K.; Barash, Y.; Schuster, S. J.; Thomas-Tikhonenko, A.
10.1101/2023.02.19.529123 — immunology — Posted on 2023-02-26
404 Top-down Proteomics of Myosin Light Chain Isoforms Define Chamber-Specific Expression in the Human Heart
Bayne, E. F.; Rossler, K. J.; Gregorich, Z. R.; Aballo, T. J.; Roberts, D. S.; Chapman, E. A.; Guo, W.; Ralphe, J. C.; Kamp, T. J.; Ge, Y.
10.1101/2023.01.26.525767 — systems biology — Posted on 2023-02-26
405 Improved Protocol for Single-Nucleus RNA-sequencing of Frozen Human Bladder Tumor Biopsies
Schmokel, S. S.; Nordentoft, I. K.; Lindskrog, S. V.; Lamy, P.; Knudsen, M.; Jensen, J. B.; Dyrskjot, L.
10.1101/2022.10.14.512220 — cancer biology — Posted on 2023-02-26
406 Epigenetic modifications mediate cultivar-specific root development and metabolic adaptation to nitrogen availability in wheat
Zhang, H.; Cui, F.; Zhao, L.; Zhang, X.; Chen, J.; Zhang, J.; Li, Y.; Niu, Y.; Wang, L.; Gao, C.; Fu, X.; Tong, Y.; Ling, H.-Q.; Li, J.; Xiao, J.
10.1101/2023.02.24.529862 — plant biology — Posted on 2023-02-26
409 Cyclic peptide structure prediction and design using AlphaFold
Rettie, S. A.; Campbell, K. V.; Bera, A. K.; Kang, A.; Koslov, S.; De La Cruz, J.; Adebomi, V.; Zhou, G.; DiMaio, F.; Ovchinnikov, S.; Bhardwaj, G.
10.1101/2023.02.25.529956 — biochemistry — Posted on 2023-02-26
411 Rapid and sensitive detection of native glycoRNAs
Hemberger, H.; Chai, P.; Lebedenko, C. G.; Caldwell, R. M.; George, B. M.; Flynn, R. A.
10.1101/2023.02.26.530106 — molecular biology — Posted on 2023-02-26
412 2019-20 H1N1 clade A5a.1 viruses have better in vitro replication compared with the co-circulating A5a.2 clade
Swanson, N. J.; Marinho, P.; Dziedzic, A.; Jedlicka, A.; Liu, H.; Fenstermacher, K.; Rothman, R. E.; Pekosz, A.
10.1101/2023.02.26.530085 — microbiology — Posted on 2023-02-26
413 BCAT1 inhibition affects CD8+ T cell activation, exhaustion, and tumoral immunity by altering iron homeostasis
Lodi, F.; Certo, M.; Elkafrawy, H.; Li, W.; Vu, H. A.; Gilbo, K.; Su, L.; Pegg, I. L.; Weiss, T.; Bühler, M.; Weller, M.; Yeh, C.; Corn, J. E.; Park, K.-S. E.; Ko, J.-H.; Behmoaras, J.; Mauro, C.; Lambrechts, D.; Papathanassiu, A. E.
10.1101/2023.02.25.530034 — immunology — Posted on 2023-02-26
414 Rescue of Auditory Function by a Single Administration of AAV-TMPRSS3 Gene Therapy in Aged Mice of Human Recessive Deafness DFNB8
Du, W.; Ergin, V.; Loeb, C.; Huang, M.; Silver, S.; Armstrong, A. M.; Huang, Z.; Gurumurthy, C.; Staecker, H.; Liu, X.; Chen, Z.-Y.
10.1101/2023.02.25.530035 — neuroscience — Posted on 2023-02-26
415 INPP5D/SHIP1 regulates inflammasome activation in human microglia
Chou, V.; Pearse, R. V.; Aylward, A. J.; Fancher, S. B.; Ashour, N.; Lee, H.; Lam, M.; Benoit, C. R.; Seyfried, N. T.; Bennett, D. A.; De Jager, P. L.; Menon, V.; Young-Pearse, T. L.
10.1101/2023.02.25.530025 — neuroscience — Posted on 2023-02-26
416 Integration of Apocarotenoid Profile and Expression Pattern of Carotenoid Cleavage Dioxygenases during Mycorrhization in Rice
Votta, C.; Wang, J. Y.; Cavallini, N.; Savorani, F.; Liew, K. X.; Lanfranco, L.; Al-Babili, S.; Fiorilli, V.
10.1101/2023.02.24.529886 — plant biology — Posted on 2023-02-26
419 The axon guidance cue SEMA3A promotes the aggressive phenotype of basal-like PDAC
Lupo, F.; Pezzini, F.; Fiorini, E.; Adamo, A.; Veghini, L.; Bevere, M.; Frusteri, C.; Delfino, P.; D'Agosto, S.; Andreani, S.; Piro, G.; Malinova, A.; De Sanctis, F.; Pasini, D.; Lawlor, R. T.; Hwang, C.-i.; Carbone, C.; Amelio, I.; Bailey, P.; Bronte, V.; Tuveson, D.; Scarpa, A.; Ugel, S.; Corbo, V.
10.1101/2023.02.25.529923 — cancer biology — Posted on 2023-02-26
420 Transcription elongation defects link oncogenic splicing factor mutations to targetable alterations in chromatin landscape
Boddu, P. C.; Gupta, A. K.; Roy, R.; De La Pena Avalos, B.; Olazabal Herrero, A.; Neuenkirchen, N.; Zimmer, J.; Chandhok, N. S.; King, D.; Nannya, Y.; Ogawa, S.; Lin, H.; Simon, M.; Dray, E.; Kupfer, G.; Verma, A. K.; Neugebauer, K. M.; Pillai, M. M.
10.1101/2023.02.25.530019 — cancer biology — Posted on 2023-02-26
421 A generalizable Cas9/sgRNA prediction model using machine transfer learning with small high-quality datasets
Ham, D. T.; Browne, T. S.; Bangalorewala, P. N.; Wilson, T.; Michael, R.; Gloor, G. B.; Edgell, D. R.
10.1101/2023.02.26.530100 — bioinformatics — Posted on 2023-02-26
422 Cure of congenital purpura fulminans via expression of engineered protein C through neonatal genome editing in mice
Togashi, T.; Baatartsogt, N.; Nagao, Y.; Kashiwakura, Y.; Hayakawa, M.; Kamoshita, N.; Hiramoto, T.; Fujiwara, T.; Morishita, E.; Nureki, O.; Ohmori, T.
10.1101/2023.02.26.530058 — bioengineering — Posted on 2023-02-26
428 Substantial Downregulation of Mitochondrial and Peroxisomal Proteins during Acute Kidney Injury revealed by Data-Independent Acquisition Proteomics
Burton, J. B.; Silva-Barbosa, A.; Bons, J.; Rose, J. P.; Pfister, K.; Simona, F.; Gandhi, T.; Reiter, L.; Bernhardt, O.; Hunter, C. L.; Goetzman, E. S.; Sims-Lucas, S.; Schilling, B.
10.1101/2023.02.26.530107 — molecular biology — Posted on 2023-02-26
431 Kiwa rescues RecBCD for anti-phage activity
Todeschini, T. C.; Wu, Y.; Naji, A.; Anandhakrishna, R. M.; Nobrega, F. L.
10.1101/2023.02.26.530102 — microbiology — Posted on 2023-02-26
432 Immediate targeting of host ribosomes by jumbo phage encoded proteins
Gerovac, M.; Chihara, K.; Wicke, L.; Bottcher, B.; Lavigne, R.; Vogel, J.
10.1101/2023.02.26.530069 — microbiology — Posted on 2023-02-26
434 Design-Rules for Stapled Alpha-Helical Peptides with On-Target In Vivo Activity: Application toMdm2/X dual antagonists
Chandramohan, A.; Josien, H.; Yuen, T.; Duggal, R.; Spiegelberg, D.; Yan, L.; Juang, Y. C. A.; Ge, L.; Aronica, P.; Kaan, H. Y. K.; Lim, Y. H.; Peier, A.; Sherborne, B.; Hochman, J.; Lin, S.; Biswas, K.; Henry, B.; Nestor, M.; Verma, C. S.; Lane, D. P.; Sawyer, T. K.; Garbaccio, R.; Kannan, S.; Brown, C. J.; Johannes, C. W.; Partridge, A. W.
10.1101/2023.02.25.530030 — biochemistry — Posted on 2023-02-26
435 A leptin-responsive hypothalamic circuit inputs to the circadian feeding network
Tang, Q.; Godschall, E.; Brennan, C. D.; Zhang, Q.; Abraham-Fan, R.-J.; Williams, S. P.; Gungul, T. B.; Onoharigho, R.; Buyukaksakal, A.; Salinas, R.; Olivieri, J. J.; Deppmann, C. D.; Campbell, J. N.; Podyma, B.; Guler, A. D.
10.1101/2023.02.24.529901 — neuroscience — Posted on 2023-02-26
437 LRRC23 loss-of-function impairs radial spoke 3 head assembly and causes defective sperm motility underlying male infertility
Hwang, J. Y.; Chai, P.; Nawaz, S.; Choi, J.; Lopez-Giraldez, F.; Hussain, S.; Bilguvar, K.; Mane, S.; Lifton, R. P.; Ahmad, W.; Zhang, K.; Chung, J.-J.
10.1101/2023.02.25.530050 — cell biology — Posted on 2023-02-26
439 Spatial transcriptomic atlas of shoot organogenesis in tomato callus
Song, X.; Guo, P.; Wang, M.; Chen, L.; Zhang, J.; Xu, M.; Liu, N.; Liu, M.; Fang, L.; Xu, X.; Gu, Y.; Xia, K.; Li, B.
10.1101/2023.02.24.529793 — cell biology — Posted on 2023-02-26
441 Recent developments in the production of 2D- and 3D colon and stomach adenocarcinomas primary cell models
Tokarchuck, I. M.; Mushii, O.; Dreus, A.; Koziaruk, A. A.; Shapochka, D. O.; Ryzhak, O. A.; Venhryk, S. O.; Golovko, I. S.; Ryabuhin, S. V.; Hanopolskyi, A. I.; Judd, D. B.; Volochnyuk, D. M.
10.1101/2023.02.26.529716 — cell biology — Posted on 2023-02-26
442 Control of human pancreatic beta cell kinome by GLP-1R biased agonism
Xiao, J.; Eleid, L.; Buenaventura, T.; Boutry, R.; Bonnefond, A.; Jones, B.; Rutter, G. A.; Froguel, P.; Tomas, A.
10.1101/2023.02.25.530040 — cell biology — Posted on 2023-02-26
443 Non-muscle myosin 2 filaments are processive in cells
Vitriol, E. A.; Quintanilla, M. A.; Tidei, J. J.; Troughton, L. D.; Cody, A.; Cisterna Irrazabal, B. A.; Jane, M. L.; Oakes, P. W.; Beach, J. R.
10.1101/2023.02.24.529920 — cell biology — Posted on 2023-02-26
444 Confinement with Myosin-II suppression increases heritable loss of chromosomes, using live-cell ChReporters
Hayes, B.; Zhu, P.; Wang, M.; Pfeifer, C.; Xia, Y.; Phan, S.; Andrechak, J.; Du, J.; Tobin, M.; Anlas, A.; Dooling, L.; Irianto, J.; Lampson, M.; Discher, D.
10.1101/2023.02.25.530049 — cell biology — Posted on 2023-02-26
449 Dynamic functional connectivity MEG features of Alzheimer's disease
Jin, H.; Ranasinghe, K.; Prahu, P.; Dale, C.; Gao, Y.; Kudo, K.; Vossel, K.; Raj, A.; Nagarajan, S.; Jiang, F.
10.1101/2023.02.23.529813 — neuroscience — Posted on 2023-02-26
451 Mechanistic insights into zearalenone-accelerated colorectal cancer in mice using integrative multi-omics approaches
Lo, E. K. K.; Wang, X.; Lee, P.-K.; Wong, H.-C.; Lee, J. C.-Y.; Gomez-Gallego, C.; Zhao, D.; El-Nezami, H.; Li, J.
10.1101/2022.09.21.508814 — cancer biology — Posted on 2023-02-26
454 Cell-type-specific regulation of APOE levels in human neurons by the Alzheimer's disease risk gene SORL1
Lee, H.; Aylward, A. J.; Pearse, R. V.; Hsieh, Y.-C.; Augur, Z. M.; Benoit, C. R.; Chou, V.; Knupp, A.; Pan, C.; Goberdhan, S.; Duong, D. M.; Seyfried, N. T.; Bennett, D. A.; Klein, H.-U.; De Jager, P. L.; Menon, V.; Young, J. E.; Young-Pearse, T. L.
10.1101/2023.02.25.530017 — neuroscience — Posted on 2023-02-25
455 Cerebellar Granule Cells Develop Non-neuronal 3D Genome Architecture over the Lifespan
Tan, L.; Shi, J.; Moghadami, S.; Wright, C. P.; Parasar, B.; Seo, Y.; Vallejo, K.; Cobos, I.; Duncan, L.; Chen, R.; Deisseroth, K.
10.1101/2023.02.25.530020 — neuroscience — Posted on 2023-02-25
456 A frontosensory circuit for visual context processing is synchronous in the theta/alpha band
Bastos, G.; Holmes, J. T.; Ross, J. M.; Rader, A. M.; Gallimore, C. G.; Peterka, D. S.; Hamm, J. P.
10.1101/2023.02.25.530044 — neuroscience — Posted on 2023-02-25
457 Human APOBEC3B promotes tumor heterogeneity in vivo including signature mutations and metastases
Durfee, C.; Temiz, N. A.; Levin-Klein, R.; Argyris, P.; Alsoe, L.; Carracedo, S.; Alonso, A.; Proehl, J.; Holzhauer, A.; Seeman, Z.; Lin, Y.-H. T.; Vogel, R. I.; Sotillo, R.; Nilsen, H.; Harris, R.
10.1101/2023.02.24.529970 — cancer biology — Posted on 2023-02-25
458 GLUT1 is redundant in hypoxic and glycolytic nucleus pulposus cells of the intervertebral disc
Johnston, S. N.; Silagi, E. S.; Madhu, V.; Nguyen, D. H.; Shapiro, I. M.; Risbud, M. V.
10.1101/2022.07.22.501129 — cell biology — Posted on 2023-02-25
459 Dynamical modeling reveals RNA decay mediates the effect of matrix stiffness on aged muscle stem cell fate
Hettinger, Z. R.; Hu, S.; Mamiya, H.; Sahu, A.; Iijima, H.; Wang, K.; Gilmer, G.; Miller, A.; Nasello, G.; D'Amore, A.; Vorp, D.; Rando, T. A.; Xing, J.; Ambrosio, F.
10.1101/2023.02.24.529950 — cell biology — Posted on 2023-02-25
462 Characterization of new highly selective pyrazolopyrimidine inhibitor of CDK7
Kovalova, M.; Havlicek, L.; Djukic, S.; Skerlova, J.; Perina, M.; Pospisil, T.; Reznickova, E.; Rezacova, P.; Jorda, R.; Krystof, V.
10.1101/2023.02.24.529844 — cancer biology — Posted on 2023-02-25
464 OME-Zarr: a cloud-optimized bioimaging file format with international community support
Moore, J.; Basurto-Lozada, D.; Besson, S.; Bogovic, J.; Brown, E. M.; Burel, J.-M.; de Medeiros, G.; Diel, E. E.; Gault, D.; Ghosh, S. S.; Gold, I.; Halchenko, Y. O.; Hartley, M.; Horsfall, D.; Keller, M. S.; Kittisopikul, M.; Kovacs, G.; Küpcü Yoldas, A.; le Tournoulx de la Villegeorges, A.; Li, T.; Liberali, P.; Linkert, M.; Lindner, D.; Lüthi, J.; Maitin-Shepard, J.; Manz, T.; McCormick, M.; Mohamed, K.; Moore, W.; Özdemir, B.; Pape, C.; Pelkmans, L.; Prete, M.; Pietzsch, T.; Preibisch, S.; Rzepka, N.; Stirling, D. R.; Striebel, J.; Tischer, C.; Toloudis, D.; Walczysko, P.; Watson, A. M
10.1101/2023.02.17.528834 — bioinformatics — Posted on 2023-02-25
466 A cataract-causing Y204X mutation of CRYβB1 promotes C-terminal degradation and higher-order oligomerization
Jing, X.; Lu, X.; Zhu, M.; Shi, L.; Wei, P.; Zhang, B.-Y.; Xu, Y.; Xiang, D.; Tang, Y.-P.; Gong, P.
10.1101/2023.02.24.529791 — biochemistry — Posted on 2023-02-25
468 Morphological trait evolution in Solanum (Solanaceae): evolutionary lability of key taxonomic characters
Hilgenhof, R.; Gagnon, E.; Knapp, S.; Aubriot, X.; Tepe, E.; Bohs, L.; Giacomin, L.; Gouvea, Y.; Martine, C.; Orejuela, A.; Orozco, C. I.; Peralta, I. E.; Sarkinen, T.
10.1101/2023.02.24.529849 — evolutionary biology — Posted on 2023-02-25
469 Colour polymorphism associated with a gene duplication in male wood tiger moths
Brien, M. N.; Orteu, A.; Yen, E. C.; Galarza, J. A.; Kirvesoja, J.; Pakkanen, H.; Wakamatsu, K.; Jiggins, C. D.; Mappes, J.
10.1101/2022.04.29.490025 — evolutionary biology — Posted on 2023-02-25
471 Oxygen-independent, hormonal control of HIF-1α regulates the developmental and regenerative growth of cardiomyocytes.
Wanschel, A.; Daiou, A.; Kuznetsoff, J.; Kurtenbach, S.; Petalidou, K.; Mouskeftara, T.; Gika, H. G.; Rodriguez, D. A.; Papadopoulos, E. I.; Siokatas, G.; Sarri, P. P.; Karava, K.; Tsivoglou, E.; Kottaridi, C.; Salerno, A. G.; Valasaki, K.; Balkan, W.; Dykxhoorn, D.; Schally, A.; Kontoyiannis, D. L.; Lazou, A.; Hatzistergos, K. E.; Hare, J.
10.1101/2022.01.31.478572 — developmental biology — Posted on 2023-02-25
472 Partial in vivo reprogramming enables injury-free intestinal regeneration via autonomous Ptgs1 induction
Kim, J.; Kim, S.; Lee, S.-Y.; Jo, B.-K.; Oh, J.-Y.; Kwon, E.-J.; Kim, K.-T.; Adpaikar, A.; Kim, E.-J.; Jung, H.-S.; Kim, H.-R.; Roe, J.-S.; Hong, C. P.; Kim, J. K.; Koo, B. K.; Cha, H.-J.
10.1101/2023.02.25.530001 — cell biology — Posted on 2023-02-25
473 Multimodal decoding of human liver regeneration
Matchett, K. P.; Wilson-Kanamori, J. W.; Portman, J. R.; Kapourani, A.; Fercoq, F.; May, S.; Mackey, J. B.; Brice, M.; Zajdel, E.; Beltran-Sierra, M.; Sutherland, E. F.; Wilson, G. C.; Wallace, S. J.; Kitto, L.; Younger, N. T.; Dobie, R.; Oniscu, G. C.; Wigmore, S. J.; Ramachandran, P.; Vallejos, C. A.; Carragher, N.; Simpson, K. J.; Kendall, T. J.; Rule, J. A.; Lee, W. J.; Hoare, M.; Weston, C. J.; Marioni, J. C.; Teichmann, S.; Bird, T. G.; Carlin, L. M.; Henderson, N. C.
10.1101/2023.02.24.529873 — cell biology — Posted on 2023-02-25
475 Structural Characterization of TRAF6 N-terminal for Therapeutic Uses
Guven, O.; Ciftci, H.; Tateishi, H.; Koga, R.; Radwan, M. O.; Sever, B.; Inoue, J.-i.; Otsuka, M.; Fujita, M.; DeMirci, H.
10.1101/2023.02.25.529911 — molecular biology — Posted on 2023-02-25
479 Retro-miRs: Novel and functional miRNAs originated from mRNA retrotransposition
Mercuri, R. L. V.; Conceicao, H. B.; Guardia, G. D. A.; Goldstein, G.; Vibranovski, M. D.; Hinske, L. C.; Galante, P. A. F.
10.1101/2023.02.24.529967 — genomics — Posted on 2023-02-25
481 Development of Cell Permeable NanoBRET Probes for the Measurement of PLK1 Target Engagement in Live Cells
Yang, X.; Smith, J. L.; Beck, M. T.; Wilkinson, J. M.; Michaud, A.; Vasta, J. D.; Robers, M. B.; Willson, T. M.
10.1101/2023.02.25.529946 — cell biology — Posted on 2023-02-25
483 Detection of Influenza virus and Streptococcus pneumoniae in air sampled from co-infected ferrets and analysis of their influence on pathogen stability
French, A. J.; Rockey, N.; Le Sage, V.; Mueller Brown, K.; Shephard, M.; Frizzell, S.; Myerburg, M. M.; Hiller, N. L.; Lakdawala, S.
10.1101/2023.02.24.529988 — microbiology — Posted on 2023-02-25
485 In situ characterization of late Chikungunya virus replication organelle
Girard, J.; Le-Bihan, O.; Lai-Kee-Him, J.; Girleanu, M.; Bernard, E.; Castellarin, C.; Neyret, A.; Spehner, D.; Holy, X.; Favier, A.-L.; Briant, L.; Bron, P.
10.1101/2023.02.25.530016 — molecular biology — Posted on 2023-02-25
490 Mycobacterium tuberculosis methyltransferase perturbs host epigenetic programming to promote bacterial survival
Singh, P. R.; Dadireddy, V.; Udupa, S.; Kalladi, S.; Shee, S.; Khosla, S.; Rajmani, R.; Singh, A.; Ramakumar, S.; Nagaraja, V.
10.1101/2023.02.24.529973 — microbiology — Posted on 2023-02-25
491 Identifying the core genome of the nucleus-forming bacteriophage family and characterization of Erwinia phage RAY
Prichard, A.; Lee, J.; Laughlin, T. G.; Lee, A.; Thomas, K. P.; Sy, A.; Spencer, T.; Asavavimol, A.; Cafferata, A.; Cameron, M.; Chiu, N.; Davydov, D.; Desai, I.; Diaz, G.; Guereca, M.; Hearst, K.; Huang, L.; Jacobs, E.; Johnson, A.; Kahn, S.; Koch, R.; Martinez, A.; Norquist, M.; Pau, T.; Prasad, G.; Saam, K.; Sandhu, M.; Sarabia, A. J.; Schumaker, S.; Sonin, A.; Uyeno, A.; Zhao, A.; Corbett, K.; Pogliano, K.; Meyer, J.; Grose, J. H.; Villa, E.; Dutton, R.; Pogliano, J.
10.1101/2023.02.24.529968 — microbiology — Posted on 2023-02-25
492 Efficient and scalable de novo protein design using a relaxed sequence space
Frank, C. J.; Khoshouei, A.; de Stigter, Y.; Schiewitz, D.; Feng, S.; Ovchinnikov, S.; Dietz, H.
10.1101/2023.02.24.529906 — synthetic biology — Posted on 2023-02-25
498 Escherichia coli SPFH membrane microdomain proteins HflKC contribute to aminoglycoside and oxidative stress tolerance
Wessel, A. K.; Yoshii, Y.; Reder, A.; Boudjemaa, R.; Szczesna, M.; Betton, J.-M.; Bernal-Bayard, J.; Beloin, C.; Lopez, D.; Volker, U.; Ghigo, J.-M.
10.1101/2022.07.25.501378 — microbiology — Posted on 2023-02-25
499 Microglial TNFα controls GABAAR plasticity, slow waves and memory consolidation during sleep
Pinto, M. J.; Bizien, L.; Fabre, J. M.; Thukanovic, N.; Cottin, L.; Lepetz, V.; Henderson, F.; Pujol, M.; Sala, R. W.; Tarpin, T.; Popa, D.; Triller, A.; Lena, C.; Fabre, V.; Bessis, A.
10.1101/2022.02.21.481254 — neuroscience — Posted on 2023-02-25
500 Small Molecules Restore Azole Activity Against Drug-Tolerant and Drug-Resistant Candida Isolates
Alabi, P. E.; Gautier, C.; Murphy, T. P.; Gu, X.; Lepaas, M.; Aimanianda, V.; Sello, J. K.; Ene, I. V.
10.1101/2022.03.31.486631 — microbiology — Posted on 2023-02-25
503 Phenotypic deconvolution in heterogeneous cancer cell populations using drug screening data
Köhn-Luque, A.; Myklebust, E. M.; Tadele, D. S.; Giliberto, M.; Schmiester, L.; Noory, J.; Harivel, E.; Arsenteva, P.; Mumenthaler, S. M.; Schjesvold, F.; Tasken, K.; Enserink, J. M.; Leder, K.; Frigessi, A.; Foo, J.
10.1101/2022.01.17.476604 — cancer biology — Posted on 2023-02-25
506 African army ants at the forefront of virome surveillance in a remote tropical forest
Fritz, M.; Reggiardo, B.; Filloux, D.; Claude, L.; Fernandez, E.; Mahe, F.; Kraberger, S.; Custer, J. M.; Becquart, P.; Ndong Mebaley, T.; Bohou Kombila, L.; Lenguiya, L. H.; Boundenga, L.; Mombo, I. M.; Maganga, G. D.; Niama, F. R.; Koumba, J.-S.; Ogliastro, M.; Yvon, M.; Martin, D.; Blanc, S.; Varsani, A.; Leroy, E.; Roumagnac, P.
10.1101/2022.12.13.520061 — microbiology — Posted on 2023-02-25
507 Homotopic local-global parcellation of the human cerebral cortex from resting-state functional connectivity
Yan, X.; Kong, R.; Xue, A.; Yang, Q.; Orban, C.; An, L.; Holmes, A. J.; Qian, X.; Chen, J.; Zuo, X.-N.; Zhou, J. H.; Fortier, M. V.; Tan, A. P.; Gluckman, P.; Chong, Y. S.; Meaney, M.; Bzdok, D.; Eickhoff, S. B.; Yeo, B. T. T.
10.1101/2022.10.25.513788 — neuroscience — Posted on 2023-02-25
510 Multi-modal Proteomic Characterization of Lysosomal Function and Proteostasis in Progranulin-Deficient Neurons
Hasan, S.; Fernandopulle, M. S.; Humble, S. W.; Frankenfield, A. M.; Li, H.; Prestil, R.; Johnson, K. R.; Ryan, B. J.; Wade-Martins, R.; Ward, M. E.; Hao, L.
10.1101/2023.02.24.529955 — neuroscience — Posted on 2023-02-24
512 Bioenergetic-Related Gene Expression in the Hippocampus Predicts Internalizing vs. Externalizing Behavior in a F2 Cross of Selectively-Bred Rats
Hebda-Bauer, E. K.; Hagenauer, M. H.; Blandino, P.; Meng, F.; Chitre, A. S.; Ozel, A. B.; Arakawa, K.; Flagel, S. B.; Watson, S. J.; Palmer, A. A.; Li, J.; Akil, H.
10.1101/2022.07.14.500129 — neuroscience — Posted on 2023-02-24
515 Cortical cell assemblies and their underlying connectivity: an in silico study
Ecker, A.; Egas Santander, D.; Bolanos Puchet, S.; Isbister, J. B.; Reimann, M. W.
10.1101/2023.02.24.529863 — neuroscience — Posted on 2023-02-24
516 Obstacle avoidance in aerial pursuit
Brighton, C. H.; Kempton, J. A.; France, L. A.; KleinHeerenbrink, M.; Minano, S.; Taylor, G. K.
10.1101/2023.01.23.525170 — zoology — Posted on 2023-02-24
518 Cancer prevalence is related to body mass and lifespan in tetrapods and remarkably low in turtles
Bulls, S.; Platner, L.; Ayub, W.; Moreno, N.; Arditi, J.-P.; Dreyer, S.; McCain, S.; Wagner, P.; Burgstaller, S.; Davis, L. R.; Bruins - van Sonsbeek, L. G. R.; Fischer, D.; Lynch, V. J.; Claude, J.; Glaberman, S.; Chiari, Y.
10.1101/2022.07.12.499088 — evolutionary biology — Posted on 2023-02-24
519 Reduced parasite burden in feral honeybee colonies
Kohl, P. L.; D'Alvise, P.; Rutschmann, B.; Roth, S.; Remter, F.; Steffan-Dewenter, I.; Hasselmann, M.
10.1101/2022.07.18.500457 — ecology — Posted on 2023-02-24
520 Disease diagnostics using machine learning of immune receptors
Zaslavsky, M. E.; Craig, E.; Michuda, J. K.; Ram-Mohan, N.; Lee, J.-Y.; Nguyen, K. D.; Hoh, R. A.; Pham, T. D.; Parsons, E. S.; Macwana, S. R.; DeJager, W.; Roskin, K. M.; Cunningham-Rundles, C.; Moody, M. A.; Haynes, B. F.; Goldman, J. D.; Heath, J. R.; Balboni, I.; Utz, P. J.; Nadeau, K. C.; Pinsky, B. A.; Blish, C. A.; Merrill, J. T.; Guthridge, J. M.; James, J. A.; Yang, S.; Tibshirani, R.; Kundaje, A.; Boyd, S. D.
10.1101/2022.04.26.489314 — immunology — Posted on 2023-02-24
521 Multimodal interrogation of ventral pallidum projections reveals projection-specific signatures and opposite roles in cocaine withdrawal
Bernat, N.; Campbell, R.; Nam, H.; Basu, M.; Odesser, T.; Elyasaf, G.; Engeln, M.; Chandra, R.; Golden, S.; Ament, S.; Lobo, M. K.; Kupchik, Y.
10.1101/2021.11.15.468637 — neuroscience — Posted on 2023-02-24
522 Adolescent neurostimulation of dopamine circuit reverses genetic deficits in frontal cortex function
Mastwal, S.; Li, X.; Stowell, R. D.; Manion, M.; Zhang, W.; Kim, N.-S.; Yoon, K.-J.; Song, H.; Ming, G.-L.; Wang, K. H.
10.1101/2023.02.03.526987 — neuroscience — Posted on 2023-02-24
526 Binding and sequestration of poison frog alkaloids by a plasma globulin
Alvarez-Buylla, A.; Moya Garzon, M. D.; Rangel, A. E.; Tapia, E. E.; Tanzo, J.; Soh, H. T.; Coloma, L. A.; Long, J. Z.; O'Connell, L. A.
10.1101/2022.11.22.517437 — physiology — Posted on 2023-02-24
527 Treating muscle and brain alike: benefits of GSK3 inhibition in mdx mice
Marcella, B. M.; Copeland, E. N.; Hamstra, S. I.; Hockey, B.; Braun, J. L.; Geromella, M. S.; Whitley, K. C.; Watson, C. J.; Baranowski, B. J.; Maddalena, L. A.; Silvera, S.; Baranowski, R. W.; Ochoa, E. C.; Wasilewicz, L.; Cleverdon, R. E.; Beaudette, S.; Vandenboom, R.; Roy, B. D.; Stuart, J. A.; MacNeil, A. J.; MacPherson, R. E.; Fajardo, V.
10.1101/2022.02.16.480726 — physiology — Posted on 2023-02-24
529 Mass Spectrometry Reveals that Oxysterols are Secreted from Non-Alcoholic Fatty Liver Disease Induced Organoids
Komurcu, K. S.; Wilhelmsen, I.; Thorne, J. L.; Krauss, S.; Wilson, S. R.; Aizenshtadt, A.; Roberg-Larsen, H.
10.1101/2023.02.22.529551 — biochemistry — Posted on 2023-02-24
534 Fear and foraging in the ecosystem size spectrum generate diversity in fish life histories
Kindsvater, H. K.; Juan Jorda, M. J.; Dulvy, N. K.; Horswill, C.; Matthiopoulos, J.; Mangel, M.
10.1101/2022.08.20.504655 — ecology — Posted on 2023-02-24
535 Vitamin K-dependent carboxylation regulates calcium flux and adaptation to metabolic stress in β-cells
Lacombe, J.; Guo, K.; Bonneau, J.; Faubert, D.; Gioanni, F.; Vivoli, A.; Muir, S. M.; Hezzaz, S.; Poitout, V.; Ferron, M.
10.1101/2022.05.13.491370 — cell biology — Posted on 2023-02-24
536 Defining the structure, signals, and cellular elements of the gastric mesenchymal niche
Manieri, E.; Tie, G.; Seruggia, D.; Madha, S.; Maglieri, A. H.; Huang, K.; Fujiwara, Y.; Zhang, K.; Orkin, S. H.; McCarthy, N.; Shivdasani, R. A.
10.1101/2023.02.11.527728 — cell biology — Posted on 2023-02-24
537 Comprehensive interrogation of human skeletal muscle reveals a dissociation between insulin resistance and mitochondrial capacity
Whytock, K. L.; Pino, M. F.; Sun, Y.; Yu, G.; De Carvalho, F. G.; Yeo, R. X.; Vega, R. B.; Parmar, G. S.; Divoux, A.; Kapoor, N.; Yi, F.; Cornnell, H.; Patten, D. A.; Harper, M.-E.; Gardell, S. J.; Smith, S. R.; Walsh, M. J.; Sparks, L. M.
10.1101/2023.02.24.529750 — molecular biology — Posted on 2023-02-24
539 Laminin alpha 5 - induced mechanical homeostasis modulates retinal epithelium functionality
Kozyrina, A. N.; Piskova, T.; Doolaar, I.; Prapty, T.; Semeraro, F.; Yam, L. S.; Haraszti, T.; Hubert, M.; Smith, A.-S.; Di Russo, J.
10.1101/2023.02.24.529913 — biophysics — Posted on 2023-02-24
542 PhageDPO: Phage Depolymerase Finder
Vieira, M. F.; Duarte, J.; Domingues, R.; Oliveira, H.; Dias, O.
10.1101/2023.02.24.529883 — bioinformatics — Posted on 2023-02-24
543 Tenascin-C activation of lung fibroblasts in a 3D synthetic lung extracellular matrix mimic
Kundu, A. N.; Dougan, C. E.; Mahmoud, S.; Kilic, A.; Panagiotou, A.; Irakoze, N.; Richbourg, N.; Peyton, S. R.
10.1101/2023.02.24.529926 — bioengineering — Posted on 2023-02-24
545 A Recombinant Approach For Stapled Peptide Discovery YieldsInhibitors of the RAD51 Recombinase
Pantelejevs, T.; Zuazua-Villar, P.; Koczy, O.; Counsell, A. J.; Walsh, S. J.; Robertson, N. S.; Spring, D. R.; Downs, J. A.; Hyvonen, M.
10.1101/2023.02.24.529929 — biochemistry — Posted on 2023-02-24
546 Cooperativity between H3.3K27M and PDGFRA poses multiple therapeutic vulnerabilities in human iPSC-derived diffuse midline glioma avatars
Skinner, K. R.; Koga, T.; Miki, S.; Gruener, R. F.; Grigore, F.-N.; Torii, E. H.; Seelig, D. M.; Suzuki, Y.; Kawauchi, D.; Lin, B.; Malicki, D. M.; Chen, C. C.; Benveniste, E. N.; Patel, R. P.; McFarland, B. C.; Huang, R. S.; Jones, C.; Mackay, A.; Miller, C. R.; Furnari, F. B.
10.1101/2023.02.24.528982 — genomics — Posted on 2023-02-24
547 A chromosome-level genome assembly of amodel conifer plant, the Japanese cedar,Cryptomeria japonica D. Don
Fujino, T.; Yamaguchi, K.; Yokoyama, T. T.; Hamanaka, T.; Harazono, Y.; Kamada, H.; Kobayashi, W.; Ujino-Ihara, T.; Uchiyama, K.; Matsumoto, A.; Izuno, A.; Tsumura, Y.; Toyoda, A.; Shigenobu, S.; Moriguchi, Y.; Ueno, S.; Kasahara, M.
10.1101/2023.02.24.529822 — genomics — Posted on 2023-02-24
552 Ecogenomics reveals distinctive viral-bacterial communities in the surface microlayer of a natural surface slick
Rahlff, J.; Wietz, M.; Giebel, H.-A.; Bayfield, O.; Nilsson, E.; Bergstroem, K.; Kieft, K.; Anantharaman, K.; Ribas-Ribas, M.; Wurl, O.; Hoetzinger, M.; Antson, A.; Holmfeldt, K.
10.1101/2023.02.24.528798 — microbiology — Posted on 2023-02-24
553 Antibody landscape of C57BL/6 mice cured of B78 melanoma via immunotherapy
Hoefges, A.; McIlwain, S. J.; Erbe, A. K.; Mathers, N. N.; Xu, A. E.; Melby, D.; Tetreault, K.; Le, T. Q.; Kim, K.; Pinapati, R. S.; Garcia, B.; Patel, J.; Heck, M.; Feils, A.; Tsarovsky, N.; Hank, J. A.; Morris, Z. S.; Ong, I. M.; Sondel, P. M.
10.1101/2023.02.24.529012 — immunology — Posted on 2023-02-24
554 IFN-lambda is protective against lethal oral Toxoplasma gondii infection
Murillo-Leon, M.; Bastidas-Quintero, A. M.; Endres, N. S.; Schnepf, D.; Delgado-Betancourt, E.; Ohnemus, A.; Taylor, G. A.; Schwemmle, M.; Staeheli, P.; Steinfeldt, T.
10.1101/2023.02.24.529861 — immunology — Posted on 2023-02-24
556 G-quadruplexes are promoter elements controlling nucleosome exclusion and RNA polymerase II pausing
Esnault, C.; Garcia-Oliver, E.; Zine El Aabidine, A.; Robert, M.-C.; Magat, T.; Gawron, K.; Basyuk, E.; Karpinska, M.; Pigeot, A.; Cucchiarini, A.; Luo, Y.; Verga, D.; Mourad, R.; Radulescu, O.; Mergny, J.-L.; Bertrand, E.; Andrau, J.-C.
10.1101/2023.02.24.529838 — genomics — Posted on 2023-02-24
557 Pro-inflammatory polarization and colorectal cancer modulate alternative and intronic polyadenylation in primary human macrophages
Wilton, J.; Mendonca, F. L. d.; Pereira-Castro, I.; Tellier, M.; Nojima, T.; Costa, A. M.; Freitas, J.; Murphy, S.; Oliveira, M. J.; Proudfoot, N. J.; Moreira, A.
10.1101/2023.02.24.529734 — molecular biology — Posted on 2023-02-24
558 A validation approach for computational models of TMSinduced brain currents using motor evoked potentials
Petrov, P. I.; Vink, J.; Mandija, S.; van den Berg, N. A. T.; Dijkhuizen, R. M.; Neggers, S. F. W.
10.1101/2023.02.24.528183 — neuroscience — Posted on 2023-02-24
559 Hippocampal engrams generate flexible behavioral responses and brain-wide network states
Dorst, K. E.; Senne, R. A.; Diep, A. H.; de Boer, A. R.; Suthard, R. L.; Leblanch, H.; Ruesch, E. A.; Skelton, S.; McKissick, O. P.; Bladon, J. H.; Ramirez, S.
10.1101/2023.02.24.529744 — neuroscience — Posted on 2023-02-24
560 SP2G: an imaging and analysis pipeline revealing the inter and intra-patient migratory diversity of glioblastoma
Crestani, M.; Kakogiannos, N.; Iannelli, F.; Dini, T.; Maderna, C.; Giannotta, M.; Pelicci, G.; Maiuri, P.; Monzo, P.; Gauthier, N. C.
10.1101/2023.02.24.529679 — biophysics — Posted on 2023-02-24
563 Optineurin provides a mitophagy contact site for TBK1 activation
Yamano, K.; Sawada, M.; Kikuchi, R.; Nagataki, K.; Kojima, W.; Sugihara, A.; Fujino, T.; Tanaka, K.; Hayashi, G.; Murakami, H.; Matsuda, N.
10.1101/2023.02.24.529790 — cell biology — Posted on 2023-02-24
564 Insights into a viral motor: the structure of the HK97 packaging termination assembly
Hawkins, D. E. D. P.; Bayfield, O. W.; Fung, H.; Grba, D.; Huet, A.; Conway, J.; Antson, A.
10.1101/2023.02.24.529869 — molecular biology — Posted on 2023-02-24
566 The intracellular lifestyle of an archaeal symbiont
Hamm, J. N.; Liao, Y.; von Kügelgen, A.; Dombrowski, N.; Landers, E.; Brownlee, C.; Johansson, E. M. V.; Whan, R. M.; Baker, M. A. B.; Baum, B.; Bharat, T. A. M.; Duggin, I. G.; Spang, A.; Cavicchioli, R.
10.1101/2023.02.24.529834 — microbiology — Posted on 2023-02-24
569 Cell migration simulator-based biomarkers for glioblastoma
Hou, J. J.; McMahon, M.; Sarkaria, J. N.; Chen, C. C.; Odde, D. J.
10.1101/2023.02.24.529880 — bioengineering — Posted on 2023-02-24
570 RNA in extracellular vesicles during adolescence reveal immune, energetic and microbial imprints of early life adversity.
Korobkova, L.; Morin, E. L.; Aoued, H.; Sannigrahi, S.; Garza, K. M.; Siebert, E. R.; Walum, H.; Cabeen, R. P.; Sanchez, M. M.; Dias, B. G.
10.1101/2023.02.23.529808 — zoology — Posted on 2023-02-24
571 Multi-view learning to unravel the different levels underlying hepatitis B vaccine response
Affaticati, F.; Bartholomeus, E.; Mullan, K.; Van Damme, P.; Beutels, P.; Ogunjimi, B.; Laukens, K.; Meysman, P.
10.1101/2023.02.23.529670 — systems biology — Posted on 2023-02-24
574 A bulk-surface moving-mesh finite element method for modelling cell migration pathways
Madzvamuse, A.; Hernandez-Aristizabal, D.; Garzon-Alvarado, D. A.; Duque-Daza, C. A.
10.1101/2023.02.23.529823 — biophysics — Posted on 2023-02-24
577 Machine learning on large scale perturbation screens for SARS-CoV-2 host factors identifies β-catenin/CBP inhibitor PRI-724 as a potent antiviral
Kelch, M. A.; Vera-Guapi, A. L.; Beder, T.; Oswald, M.; Hiemisch, A.; Beil, N.; Wajda, P.; Ciesek, S.; Erfle, H.; Toptan, T.; König, R.
10.1101/2023.02.23.529833 — microbiology — Posted on 2023-02-24
578 Klebsiella pneumoniae causes bacteremia using factors that mediate tissue-specific fitness and resistance to oxidative stress
Holmes, C. L.; Wilcox, A. E.; Forsyth, V.; Smith, S. N.; Moricz, B. S.; Unverdorben, L. V.; Mason, S.; Wu, W.; Zhao, L.; Mobley, H. L. T.; Bachman, M. A.
10.1101/2023.02.23.529827 — microbiology — Posted on 2023-02-24
580 Anesthesia suppressed gastric myoelectric power in the ferret
Tomaselli, L.; Sciullo, M.; Fulton, S.; Yates, B. J.; Fisher, L. E.; Ventura, V.; Horn, C. C.
10.1101/2023.02.23.529745 — neuroscience — Posted on 2023-02-24
582 Synthetic Cooling Agent in Oral Nicotine Pouch Products Marketed as "Flavor Ban Approved"
Jabba, S. V.; Erythropel, H. C.; Woodrow, J. G.; Anastas, P. T.; O'Malley, S.; Krishnan-sarin, S.; Zimmerman, J. B.; Jordt, S. E.
10.1101/2023.02.23.529797 — pharmacology and toxicology — Posted on 2023-02-24
586 Isolation may select for earlier and higher peak viral load but shorter duration in SARS-CoV-2 evolution
Sunagawa, J.; Kim, K. S.; Park, H.; Komorizono, R.; Choi, S.; Torres, L. R.; Woo, J.; Jeong, Y. D.; Hart, W. S.; Thompson, R. N.; Aihara, K.; Iwami, S.; Yamaguchi, R.
10.1101/2023.02.23.529742 — evolutionary biology — Posted on 2023-02-24
587 Incomplete transcriptional dosage compensation of vertebrate sex chromosomes is balanced by post-transcriptional compensation.
Lister, N. C.; Milton, A. M.; Patel, H. R.; Waters, S.; Hanrahan, B. J.; McIntyre, K. L.; Livernois, A. M.; Wee, L. K.; Ringel, A. R.; Mundlos, S.; Robson, M. I.; Shearwin-Whyatt, L.; Grutzner, F.; Marshall Graves, J. A.; Ruiz-Herrera, A.; Waters, P. D.
10.1101/2023.02.23.529605 — evolutionary biology — Posted on 2023-02-24
590 EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells
van de Kooij, B.; Schreuder, A.; Pavani, R. S.; Garzero, V.; van Hoeck, A.; San Martin Alonso, M.; Koerse, D.; Wendel, T. J.; Callen, E.; Boom, J.; Mei, H.; Cuppen, E.; Nussenzweig, A.; van Attikum, H.; Noordermeer, S. M.
10.1101/2023.02.24.529205 — molecular biology — Posted on 2023-02-24
591 Optimized SMRT-UMI protocol produces highly accurate sequence datasets from diverse populations - application to HIV-1 quasispecies
Westfall, D. H.; Deng, W.; Pankow, A.; Murrell, H.; Chen, L.; Zhao, H.; Williamson, C.; Rolland, M. M.; Murrell, B.; Mullins, J. I.
10.1101/2023.02.23.529831 — molecular biology — Posted on 2023-02-24
592 Multiviral Quartet Nanocages Elicit Broad Anti-Coronavirus Responses for Proactive Vaccinology
Hills, R. A.; Tan, T. K.; Cohen, A. A.; Keefe, J. R.; Keeble, A. H.; Gnanapragasam, P. N.; Storm, K. N.; Hill, M. L.; Liu, S.; Gilbert-Jaramillo, J.; Afzal, M.; Napier, A.; James, W. S.; Bjorkman, P. J.; Townsend, A. R.; Howarth, M.
10.1101/2023.02.24.529520 — immunology — Posted on 2023-02-24
593 Vagus nerve stimulation using an endovascular electrode array
Nicolai, E. N.; Arturo Larco, J.; Madhani, S. I.; Asirvatham, S. J.; Chang, S.-y.; Ludwig, K. A.; Savastano, L. E.; Worrell, G. A.
10.1101/2023.02.23.529747 — neuroscience — Posted on 2023-02-24
595 Cellular and molecular signatures of motherhood in the adult and ageing brain
Duarte Guterman, P.; Richard, J.; Lieblich, S.; Eid, R.; Lamers, Y.; Galea, L.
10.1101/2023.02.24.529879 — neuroscience — Posted on 2023-02-24
598 Not only age affects cardiovascular parameters, salivary biomarkers, and their correlation, but the level of physical conditioning changes this behavior in the elderly
de Camargos, P. J. d. V.; Justino, A. B.; Goncalves, L. C. O.; Barros, R. J. S. d.; Bortolini, M. J. S.; Espindola, F. S.; Magalhaes Neto, A. M. d.
10.1101/2023.02.24.529896 — physiology — Posted on 2023-02-24
600 Polarimetric response of second harmonic generation in microscopy of partially oriented chiral fibrillar structures
Alizadeh, M.; Habach, F.; Maciulis, M.; Kontenis, L.; Bagdonas, S.; Krouglov, S.; Baranauskas, V.; Bulotiene, D.; Karabanovas, V.; Rotomskis, R.; Akens, M. K.; Barzda, V.
10.1101/2023.02.23.529792 — biophysics — Posted on 2023-02-24
604 An efficient method for high molecular weight bacterial DNA extraction suitable for shotgun metagenomics from skin swabs
Serghiou, I. R.; Baker, D.; Evans, R.; Dalby, M. J.; Kiu, R.; Trampari, E.; Phillips, S.; Watt, R.; Atkinson, T.; Murphy, B.; Hall, L. J.; Webber, M. A.
10.1101/2023.02.23.529690 — genomics — Posted on 2023-02-24
606 LINE-associated cryptic splicing induces dsRNA-mediated interferon response and tumor immunity
Zheng, R.; Dunlap, M.; Lyu, J.; Gonzalez-Figueroa, C.; Bobkov, G.; Harvey, S. E.; Chan, T. W.; Quinones-Valdez, G.; Choudhury, M.; Vuong, A.; Flynn, R. A.; Chang, H. Y.; Xiao, X.; Cheng, C.
10.1101/2023.02.23.529804 — genomics — Posted on 2023-02-24
607 Signatures of co-evolution and co-regulation in the CYP3A and CYP4F genes in humans
Richard-St-Hilaire, A.; Gamache, I.; Pelletier, J.; Grenier, J.-C.; Poujol, R.; Hussin, J. G.
10.1101/2023.02.23.529697 — genetics — Posted on 2023-02-24
610 Interplay between pollution and avian influenza virus infection risk in shorebirds and waterfowl
Ross, T. A.; Zhang, J.; Wille, M.; Asimakopoulos, A. G.; Jaspers, V.; Klaassen, M.
10.1101/2023.02.23.529812 — ecology — Posted on 2023-02-24
614 Insulin B peptide-MHC class II-specific chimeric antigen 1 receptor-Tregs prevent autoimmune diabetes
Spanier, J. A.; Fung, V.; Wardell, C. M.; Alkhatib, M. H.; Chen, Y.; Swanson, L. A.; Dwyer, A. J.; Weno, M. E.; Silva, N.; Mitchell, J. S.; Orban, P. C.; Mojibian, M.; Verchere, C. B.; Fife, B. T.; Levings, M. K.
10.1101/2023.02.23.529737 — immunology — Posted on 2023-02-24
615 Enhanced inflammatory signaling driven by metabolic switch in Aicardi-Goutieres syndrome
Batignes, M.; Luka, M.; Jagtap, S.; de Cevins, C.; Nemazanyy, I.; Fali, T.; Garcia-Paredes, V.; Carbone, F.; Perot, B. P.; Neven, B.; Bader-Meunier, B.; Quartier dit Maire, P.; Hully, M.; Belot, A.; Lepelley, A.; Fremond, M.-L.; Crow, Y. J.; Fischer, A.; Menager, M. M.
10.1101/2023.02.23.529707 — immunology — Posted on 2023-02-24
616 Epigenetic regulation of innate immune genes and enhanced interleukin-10 expression underlie chronic subclinical Plasmodium chabaudi infection
de Souza Silva, L.; Nguyen, Y. A. H.; Monks, B. G.; Forconi, C. S.; Crabtree, J. N.; Rodriguez, T.; Tamburro, N. D. P.; Sontheimer, E. J.; Horvath, G. L.; Abdullah, Z.; Latz, E.; Caffrey, D. R.; Kurt-Jones, E.; Gazzinelli, R. T.; Fitzgerald, K. A.; Golenbock, D. T.
10.1101/2023.02.23.529826 — immunology — Posted on 2023-02-24
617 The scale-invariant covariance spectrum of brain-wide activity
Wang, Z.; Mai, W.; Chai, Y.; Qi, K.; Ren, H.; Shen, C.; Zhang, S.; Hu, Y.; Wen, Q.
10.1101/2023.02.23.529673 — neuroscience — Posted on 2023-02-24
619 Neuroprotective effects of hepatoma-derived growth factor in models of Huntington's disease
Voelkl, K.; Gutierrez-Angel, S.; Keeling, S.; Koyuncu, S.; Arzberger, T.; Vilchez, D.; Klein, R.; Dudanova, I.
10.1101/2023.02.23.529222 — neuroscience — Posted on 2023-02-24
620 Chronic administration of XBD173 ameliorates cognitive deficits and neuropathology via 18 kDa translocator protein (TSPO) in a mouse model of Alzheimer disease
Pradhan, A. K.; Neumueller, T.; Klug, C.; Fuchs, S.; Schlegel, M.; Ballmann, M.; Tartler, K. J.; Pianos, A.; Garcia-Sanchez, M.; Liere, P.; Schumacher, M.; Kreutzer, M.; Rupprecht, R.; Rammes, G.
10.1101/2023.02.23.529740 — neuroscience — Posted on 2023-02-24
621 Release of extracellular matrix components after human traumatic brain injury
Bambrick, M.; Johnson, M. D.; Esko, J. D.; Choudhury, B.; Gomez Toledo, A.; Staley, K. J.; Duhaime, A.-C.
10.1101/2023.02.23.529754 — neuroscience — Posted on 2023-02-24
624 In vitro and in vivo effects of zoledronate on senescence and senescence-associated secretory phenotype markers
Samakkarnthai, P.; Saul, D.; Zhang, L.; Aversa, Z.; Doolittle, M. L.; Sfeir, J.; Kaur, J.; Atkinson, E.; Edwards, J.; Russell, G.; Pignolo, R.; Kirkland, J.; Tchkonia, T.; Niedernhofer, L.; Monroe, D.; LeBrasseur, N.; Farr, J.; Robbins, P. D.; Khosla, S.
10.1101/2023.02.23.529777 — physiology — Posted on 2023-02-24
626 Single cell and spatial alternative splicing analysis with long read sequencing
Fu, Y.; Kim, H.; Adams, J. I.; Grimes, S. M.; Huang, S.; Lau, B.; Sathe, A.; Hess, P.; Ji, H.; Zhang, N.
10.1101/2023.02.23.529769 — bioinformatics — Posted on 2023-02-24
627 How subjective idea valuation energizes and guides creative idea generation
Lopez-Persem, A.; Moreno Rodriguez, S.; Ovando-Tellez, M.; Bieth, T.; Guiet, S.; Brochard, J.; Volle, E.
10.1101/2022.08.02.502491 — neuroscience — Posted on 2023-02-24
628 A Latent Clinical-anatomical Dimension Relating Metabolic Syndrome to Brain Morphology - Evidence from a Multivariate Imaging Analysis of 40,087 Individuals
Petersen, M.; Hoffstaedter, F.; Naegele, F. L.; Mayer, C.; Schell, M.; Rimmele, D. L.; Zyriax, B.-C.; Zeller, T.; Kuehn, S.; Gallinat, J.; Fiehler, J.; Twerenbold, R.; Omidvarnia, A.; Patil, K.; Eickhoff, S. B.; Thomalla, G.; Cheng, B.
10.1101/2023.02.22.529531 — neuroscience — Posted on 2023-02-24
629 Charting the Heterogeneity of Colorectal Cancer Consensus Molecular Subtypes using Spatial Transcriptomics
Valdeolivas, A.; Amberg, B.; Giroud, N.; Richardson, M.; Galvez, E. J. C.; Badillo, S.; Julien-Laferriere, A.; Turos, D.; Voith von Voithenberg, L.; Wells, I.; Lo, A. A.; Yangüez, E.; Das Thakur, M.; Bscheider, M.; Sultan, M.; Kumpesa, N.; Jacobsen, B.; Bergauer, T.; Saez-Rodriguez, J.; Rottenberg, S.; Schwalie, P. C.; Hahn, K.
10.1101/2023.01.23.525135 — cancer biology — Posted on 2023-02-24
631 Chromatin accessibility associated with aquaculture relevant traits in tilapia
Mehta, T. K.; Man, A.; Ciezarek, A.; Ranson, K. J.; Penman, D.; Di-Palma, F.; Haerty, W.
10.1101/2023.02.17.528929 — genomics — Posted on 2023-02-24
632 FUSDelta14 mutation impairs normal brain development and causes systemic metabolic alterations
Godoy-Corchuelo, J. M.; Ali, Z.; Martins-Bach, A. B.; Garcia-Toledo, I.; Fernandez-Beltran, L. C.; Nair, R. R.; Spring, S.; Nieman, B.; Jimenez-Coca, I.; Bains, R. S.; Forrest, H.; Lerch, J.; Miller, K.; Fisher, E. M. C.; Cunningham, T. J.; Corrochano, S.
10.1101/2023.02.24.529858 — neuroscience — Posted on 2023-02-24
633 Tetraose steroidal glycoalkaloids from potato can provide complete protection against fungi and insects
Wolters, P. J.; Wouters, D.; Tikunov, Y. M.; Ayilalath, S.; Kodde, L. P.; Strijker, M.; Caarls, L.; Visser, R. G. F.; Vleeshouwers, V. G. A. A.
10.1101/2022.09.28.509958 — plant biology — Posted on 2023-02-24
634 Desynapsis in potato is caused by StMSH4 mutant alleles and leads to either highly uniform unreduced pollen or sterility
Clot, C. R.; Klein, D.; Koopman, J.; Schuit, C.; Engelen, C. J. M.; Hutten, R. B. C.; Brouwer, M.; Visser, R. G. F.; Jurani?, M.; Eck, H. J. V.
10.1101/2023.02.23.529759 — plant biology — Posted on 2023-02-24
636 Progeny counter mechanism in malaria parasites is linked to extracellular resources
Stuermer, V. S.; Stopper, S.; Binder, P.; Klemmer, A.; Becker, N. B.; Guizetti, J.
10.1101/2023.01.20.524890 — cell biology — Posted on 2023-02-24
637 Drosophila macrophages control systemic cytokine levels in response to oxidative stress via a non-canonical DNA damage repair signaling cascade
Hersperger, F.; Meyring, T.; Weber, P.; Chhatbar, C.; Monaco, G.; Classen, A.-K.; Dionne, M. S.; Paeschke, K.; Prinz, M.; Gross, O.; Kierdorf, K.
10.1101/2023.02.22.529599 — immunology — Posted on 2023-02-24
638 Criticality supports cross-frequency cortical-thalamic information transfer during conscious states
Toker, D.; Müller, E.; Miyamoto, H.; Riga, M. S.; Llado-Pelfort, L.; Yamakawa, K.; Artigas, F.; Shine, J. M.; Hudson, A.; Pouratian, N.; Monti, M.
10.1101/2023.02.22.529544 — neuroscience — Posted on 2023-02-24
641 Vitamin D induces SIRT1 activation through K610 deacetylation in colon cancer
Garcia-Martinez, J. M.; Chocarro-Calvo, A.; Martinez-Useros, J.; Fernandez-Acenero, M. J.; Fiuza, M. C.; Caceres-Rentero, J.; De la Vieja, A.; Barbachano, A.; Munoz, A.; Larriba, M. J.; Garcia Jimenez, C.
10.1101/2023.02.22.529558 — cancer biology — Posted on 2023-02-24
642 RevGel-seq: instrument-free single-cell RNA sequencing using a reversible hydrogel for cell-specific barcoding
Komatsu, J.; Cico, A.; Poncin, R.; LeBohec, M.; Morf, J.; Lipin, S.; Grandorge, A.; Eckert, H.; Saffarian, A.; Cathaly, L.; Guerin, F.; Majello, S.; Ulveling, D.; Vayaboury, A.; Fernandez, N.; Dimitrova, D.; Bussell, X.; Fourne, Y.; Chaumat, P.; Andre, B.; Baldivia, E.; Godet, U.; Guinin, M.; Moretto, V.; Ismail, J.; Caille, O.; Roblot, N.; Beaupere, C.; Liboz, A.; Guillemain, G.; Blondeau, B.; Walrafen, P.; Edelstein, S. J.
10.1101/2022.07.01.498266 — cell biology — Posted on 2023-02-24
643 Histone variant H2B.Z acetylation is necessary for maintenance of Toxoplasma gondii biological fitness
Vanagas, L.; Munoz, D.; Cristaldi, C.; Ganuza, A.; Najera, R.; Bonardi, M. C.; Turowski, V. R.; Guzman, F.; Deng, B.; Kim, K.; Sullivan, W. J.; Angel, S. O.
10.1101/2023.02.14.528480 — cell biology — Posted on 2023-02-24
647 Balancing grain yield trade-offs in 'Miracle-Wheat'
Abbai, R.; Golan, G.; Longin, C. F. H.; Schnurbusch, T.
10.1101/2023.02.23.529729 — plant biology — Posted on 2023-02-24
648 Retrieved Sequence Augmentation for Protein Representation Learning
Ma, C.; Zhao, H.; Zheng, L.; Xin, J.; Li, Q.; Wu, L.; Deng, Z.; Lu, Y.; Liu, Q.; Kong, L.
10.1101/2023.02.22.529597 — bioinformatics — Posted on 2023-02-24
652 An updated evolutionary history and taxonomy of Mycobacterium tuberculosis lineage 5, also called M. africanum
Sahal, M. R.; Senelle, G.; La, K.; Molina-Moya, B.; Dominguez, J. A.; Panda, T.; Cambau, E.; Refregier, G.; Guyeux, C.; Sola, C. N.
10.1101/2022.11.21.517336 — genomics — Posted on 2023-02-24
655 Multi-omic screening of invasive GBM cells in engineered biomaterials and patient biopsies reveals targetable transsulfuration pathway alterations
Garcia, J. H.; Akins, E. A.; Jain, S.; Wolf, K. J.; Zhang, J.; Choudhary, N.; Lad, M.; Shukla, P.; Gill, S.; Carson, W.; Carette, L.; Zheng, A.; Kumar, S.; Aghi, M. K.
10.1101/2023.02.23.529575 — cancer biology — Posted on 2023-02-24
656 SEG: Segmentation Evaluation in absence of Ground truth labels
Sims, Z.; Strgar, L.; Thirumalaisamy, D.; Heussner, R.; Thibault, G.; Chang, Y. H.
10.1101/2023.02.23.529809 — bioinformatics — Posted on 2023-02-24
658 Structure of the Commander endosomal trafficking complex linked to X-linked intellectual disability/Ritscher-Schinzel syndrome
Healy, M.; McNally, K.; Butkovic, R.; Chilton, M.; Kato, K.; Sacharz, J.; McConville, C.; Moody, E.; Shaw, S.; Planelles-Herrero, V.; Yadav, S.; Ross, J.; Borucu, U.; Palmer, C.; Chen, K.-E.; Croll, T.; Hall, R.; Caruana, N.; Ghai, R.; Nguyen, T.; Heesom, K.; Saitoh, S.; Berger, I.; Schaffitzel, C.; Williams, T.; Stroud, D.; Derivery, E.; Collins, B.; Cullen, P.
10.1101/2023.01.25.525455 — biochemistry — Posted on 2023-02-23
661 Exon 44 skipping in Duchenne muscular dystrophy: NS-089/NCNP-02, a dual-targeting antisense oligonucleotide
Watanabe, N.; Tone, Y.; Nagata, T.; Masuda, S.; Saito, T.; Motohashi, N.; Takagaki, K.; Aoki, Y.; Takeda, S.
10.1101/2023.02.23.529798 — cell biology — Posted on 2023-02-23
662 Treponema pallidum subsp. pallidum with an Artificially Impaired TprK Antigenic Variation System is Attenuated in the Rabbit Model of Syphilis
Romeis, E.; Lieberman, N. A. P.; Molini, B. J.; Tantalo, L. C.; Chung, B.; Phung, Q.; Avendano, C.; Vorobieva, A.; Greninger, A. L.; Giacani, L.
10.1101/2023.01.18.524629 — microbiology — Posted on 2023-02-23
663 Single-neuron spiking variability in hippocampus dynamically tracks sensory content during memory formation in humans
Waschke, L.; Kamp, F.; van den Elzen, E.; Krishna, S.; Lindenberger, U.; Rutishauser, U.; Garrett, D. D.
10.1101/2023.02.23.529684 — neuroscience — Posted on 2023-02-23
664 Parental childhood maltreatment associates with offspring left amygdala volume at early infancy
Tuulari, J. J.; Pulli, E. P.; Kataja, E.-L.; Perasto, L.; Lewis, J. D.; Karlsson, L.; Karlsson, H.
10.1101/2023.02.23.529799 — neuroscience — Posted on 2023-02-23
665 Epilepsy-associated SCN2A (Nav1.2) Variants Exhibit Diverse and Complex Functional Properties
Thompson, C. H.; Potet, F.; Abramova, T. V.; DeKeyser, J.-M.; Ghabra, N.; Vanoye, C. G.; Millichap, J. J.; George, A. L.
10.1101/2023.02.23.529757 — neuroscience — Posted on 2023-02-23
668 Yeast extract improves growth in rainbow trout (Oncorhynchus mykiss) fed a fishmeal-free diet and modulates the hepatic and distal intestine transcriptomic profile
Frohn, L.; Peixoto, D.; Guyomar, C.; Teixeira, C.; Terrier, F.; Aguirre, P.; Maman Haddad, S.; Bobe, J.; Costas, B.; Richard, N.; Pinel, K.; Skiba-Cassy, S.
10.1101/2023.02.23.529675 — physiology — Posted on 2023-02-23
671 β-cell responses to high fat feeding: A role and mechanism for redox sensing by SENP1
Lin, H.; Suzuki, K.; Smith, N.; Li, X.; Nalbach, L.; Fuentes, S.; Spigelman, A. F.; Dai, X.-Q.; Bautista, A.; Ferdaoussi, M.; Aggarwal, S.; Pepper, A. R.; Roma, L. P.; Ampofo, E.; Li, W.-h.; MacDonald, P. E.
10.1101/2022.04.05.487203 — cell biology — Posted on 2023-02-23
672 Reconstruction of TrkB complex assemblies and localizing antidepressant targets using Artificial Intelligence
Xiang, X.; Qian, C.; Yao, H.; Li, P.; Cheng, B.; Wei, D.; An, W.; Lu, Y.; Chu, M.; Wei, L.; Xu, J.; Liu, B.-F.; Liu, X.; Xia, F.
10.1101/2023.02.21.529454 — bioinformatics — Posted on 2023-02-23
677 Reconstructing the cascade of language processing in the brain using the internal computations of a transformer-based language model
Kumar, S.; Sumers, T. R.; Yamakoshi, T.; Goldstein, A.; Hasson, U.; Norman, K. A.; Griffiths, T. L.; Hawkins, R. D.; Nastase, S. A.
10.1101/2022.06.08.495348 — neuroscience — Posted on 2023-02-23
680 Role of mesolimbic cannabinoid receptor 1 in stress-driven increases in cocaine self-administration in male rats
McReynolds, J. R.; Wolf, C. P.; Starck, D. M.; Schaps, R.; Krause, L. A.; Hillard, C. J.; Mantsch, J. R.
10.1101/2022.10.28.514315 — neuroscience — Posted on 2023-02-23
682 Olfactory fear conditioning biases olfactory stem cell receptor fate
Liff, C. W.; Ayman, Y. R.; Jaeger, E. C. B.; Lee, H. S.; Kim, A.; Marlin, B. J.
10.1101/2023.02.23.529692 — neuroscience — Posted on 2023-02-23
683 Next-generation interaction proteomics for quantitative Jumbophage-bacteria interaction mapping
Fossati, A.; Mozumdar, D.; Kokontis, C. Y.; Nieweglowska, E. S.; Mendez, M.; Pelin, A.; Li, Y.; Guo, B.; Krogan, N. J.; Agard, D.; Bondy-Denomy, J.; Swaney, D. L.
10.1101/2023.01.13.523954 — systems biology — Posted on 2023-02-23
687 Combinatory EHMT and PARP inhibition induces an interferon response and a CD8 T cell-dependent tumor regression in PARP inhibitor-resistant models
Nguyen, L. L.; Watson, Z. L.; Ortega, R.; Woodruff, E. R.; Jordan, K. R.; Iwanaga, R.; Yamamoto, T. M.; Bailey, C. A.; Jeong, A. D.; Guntupalli, S.; Behbakht, K.; Gibaja, V.; Arnoult, N.; Chuong, E.; Bitler, B. G.
10.1101/2023.02.23.529773 — cancer biology — Posted on 2023-02-23
688 Performant web-based interactive visualization tool for spatially-resolved transcriptomics experiments
Sriworarat, C.; Nguyen, A. B.; Eagles, N. J.; Collado-Torres, L.; Martinowich, K.; Maynard, K. R.; Hicks, S. C.
10.1101/2023.01.28.525943 — bioinformatics — Posted on 2023-02-23
690 Isolated nuclei from frozen tissue are the superior source for single cell RNA-seq compared with whole cells.
Jiang, A.; Lehnert, K.; Reid, S. J.; Handley, R. R.; Jacobsen, J. C.; Rudiger, S. R.; McLaughlan, C.; Verma, P.; Bawden, S.; Snell, R. G.
10.1101/2023.02.19.529150 — genomics — Posted on 2023-02-23
699 Multiplex Base Editing to Protect from CD33-Directed Therapy: Implications for Immune and Gene Therapy
Borot, F.; Humbert, O.; Newby, G. A.; Fields, E.; Kohli, S.; Radtke, S.; Laszlo, G. S.; Mayuranathan, T.; Ali, A. M.; Weiss, M. J.; Yen, J. S.; Walter, R. B.; Liu, D. R.; Mukherjee, S.; Kiem, H.-P.
10.1101/2023.02.23.529353 — cell biology — Posted on 2023-02-23
700 A novel human iPSC model of COL4A1/A2 small vessel disease unveils a key pathogenic role of matrix metalloproteinases in extracellular matrix abnormalities
Al-Thani, M.; Goodwin-Trotman, M.; Bell, S.; Patel, K.; Fleming, L. K.; Vilain, C.; Abramowicz, M.; Allan, S. M.; Wang, T.; Cader, Z.; Horsburgh, K.; Van Agtmael, T.; Sinha, S.; Markus, H. S.; Granata, A.
10.1101/2023.02.23.529680 — cell biology — Posted on 2023-02-23
703 Spatial and Temporal Dynamics at an Actively Silicifying Hydrothermal System
Rasmussen, K. L.; Stamps, B. W.; Vanzin, G. F.; Ulrich, S. M.; Spear, J. R.
10.1101/2023.02.23.529738 — microbiology — Posted on 2023-02-23
704 Candida albicans stimulates the formation of a multi-receptor complex that mediates epithelial cell invasion during oropharyngeal infection
Phan, Q. T.; Solis, N. V.; Cravener, M. V.; Swidergall, M.; Lin, J.; Huang, M. Y.; Liu, H.; Singh, S.; Ibrahim, A. S.; Mazzone, M.; Mitchell, A. P.; Filler, S. G.
10.1101/2023.02.23.529756 — microbiology — Posted on 2023-02-23
705 Human A2-CAR T cells reject HLA-A2+ human islets transplanted into mice without inducing graft versus host disease
Ellis, C. E.; Mojibian, M.; Fung, V. C. W.; Skovso, S.; McIver, E.; ODwyer, S.; Webber, T. D.; Braam, M. J. S.; Ida, S.; Saber, N.; Kieffer, T. J.; Levings, M. K.
10.1101/2023.02.23.529741 — immunology — Posted on 2023-02-23
707 Layer 1 of somatosensory cortex: An important site for input to a tiny cortical compartment
Ledderose, J.; Zolnik, T. A.; Toumazou, M.; Trimbuch, T.; Rosenmund, C.; Eickholt, B. J.; Jaeger, D.; Larkum, M. E.; Sachdev, R.
10.1101/2021.11.26.469979 — neuroscience — Posted on 2023-02-23
713 The Multidrug Resistance Transporter P-glycoprotein Confers Resistance to Ferroptosis Inducers
Frye, W. J. E.; Huff, L. M.; Dalmasy, J. M. G.; Salazar, P.; Carter, R. M.; Gensler, R. T.; Esposito, D.; Robey, R. W.; Ambudkar, S. V.; Gottesman, M. M.
10.1101/2023.02.23.529736 — pharmacology and toxicology — Posted on 2023-02-23
717 Structural basis of histone H2A lysine 119 deubiquitination by Polycomb Repressive Deubiquitinase BAP1/ASXL1
Thomas, J. F.; Valencia-Sanchez, M. I.; Tamburri, S.; Gloor, S. L.; Rustichelli, S.; Godinez-Lopez, V.; De Ioannes, P.; Lee, R.; Abini-Agbomson, S.; Gretarsson, K.; Burg, J. M.; Hickman, A. R.; Sun, L.; Gopinath, S.; Taylor, H.; Meiners, M. J.; Cheek, M. A.; Rice, W.; Nudler, E.; Lu, C.; Keogh, M. C.; Pasini, D.; Armache, K.-J.
10.1101/2023.02.23.529554 — biochemistry — Posted on 2023-02-23
718 Complete Workflow for High Throughput Human Single Skeletal Muscle Fiber Proteomics
Momenzadeh, A.; Jiang, Y.; Kreimer, S.; Teigen, L. E.; Zepeda, C. S.; Haghani, A.; Mastali, M.; Song, Y.; Hutton, A.; Parker, S. J.; Van Eyk, J. E.; Sundberg, C. W.; Meyer, J. G.
10.1101/2023.02.23.529600 — biochemistry — Posted on 2023-02-23
719 The Basal and Major Pilins in the Corynebacterium diphtheriae SpaA Pilus Adopt Similar Structures that Competitively React with the Pilin Polymerase
Sue, C. K.; Cheung, N. A.; Mahoney, B. J.; McConnell, S. A.; Scully, J. M.; Fu, J. Y.; Chang, C.; Ton-That, H.; Loo, J.; Clubb, R. T.
10.1101/2023.02.23.529612 — biochemistry — Posted on 2023-02-23
724 Striatal ensemble activity in an innate naturalistic behavior
Minkowicz, S.; Mathews, M. A.; Mou, F. H.; Yoon, H.; Freda, S. N.; Cui, E. S.; Kennedy, A.; Kozorovitskiy, Y.
10.1101/2023.02.23.529669 — neuroscience — Posted on 2023-02-23
729 Extensive re-modelling of the cell wall during the development of Staphylococcus aureus bacteraemia
Douglas, E. J. A.; Palk, N.; Brignoli, T.; Altwiley, D.; Boura, M.; Laabei, M.; Recker, M.; Cheung, G. C.; Liu, R.; Hseih, R. C.; Otto, M.; O'Brien, E.; Mcloughlin, R. M.; Massey, R. C.
10.1101/2023.02.23.529713 — microbiology — Posted on 2023-02-23
730 Proteomic profiling of isolated immune synapses from primary mouse B cells
Cunha, D. M.; Hernandez-Perez, S.; Awoniyi, L. O.; Carisey, A. F.; Jacquemet, G.; Mattila, P.
10.1101/2023.02.23.529674 — immunology — Posted on 2023-02-23
731 Balancing grain yield trade-offs in 'Miracle-Wheat'
Abbai, R.; Golan, G.; Longin, C. F. H.; Schnurbusch, T.
10.1101/2023.02.23.529729 — plant biology — Posted on 2023-02-23
732 Discovery and characterization of cross-reactive intrahepatic antibodies in severe alcoholic hepatitis
Ahmadi, A. R.; Song, G.; Gao, T.; Ma, J.; Han, X.; Hu, M.-W.; Cameron, A.; Wesson, R. N.; Philosophe, B.; Ottmann, S.; King, E.; Gurakar, A.; Qi, L.; Peiffer, B.; Burdick, J.; Anders, R.; Zhou, Z.; Feng, D.; Lu, H.; Chen, C.-S.; Qian, J.; Gao, B.; Zhu, H.; Sun, Z.
10.1101/2023.02.23.529702 — pathology — Posted on 2023-02-23
733 Phosphorylation motif dictates GPCR C-terminal domain conformation and arrestin interaction
Guillien, M.; Mouhand, A.; Sagar, A.; Fournet, A.; Allemand, F.; Pereira, G. A. N.; Thureau, A.; Bernado, P.; Baneres, J.-L.; Sibille, N.
10.1101/2023.02.23.529712 — biophysics — Posted on 2023-02-23
734 Predicting the Three-dimensional Structure of the c-KIT Oncogene Promoter and the Dynamics of Strongly Coupled Guanine-Quadruplexes
Bignon, E.; Spinello, A.; Miclot, T.; D'Anna, L.; Ducani, C.; Grandemange, S.; Barone, G.; MONARI, A.; Terenzi, A.
10.1101/2023.02.23.529733 — biophysics — Posted on 2023-02-23
735 Genetic dependencies associated with transcription factor activities in human cancer cell lines
Thatikonda, V.; Supper, V.; C. Ravichandran, M.; J. Lipp, J.; S. Boghossian, A.; G. Rees, M.; M. Ronan, M.; A. Roth, J.; Grosche, S.; A. Neumüller, R.; Mair, B.; Mauri, F.; Popa, A.
10.1101/2023.02.23.529701 — bioinformatics — Posted on 2023-02-23
736 Dual-modality imaging of immunofluorescence and imaging mass cytometry for whole slide imaging with accurate single-cell segmentation
Kim, E. N.; Chen, P. Z.; Bressan, D.; Tripathi, M.; Miremadi, A.; di Pietro, M.; Coussens, L. M.; Hannon, G. J.; Fitzgerald, R. C.; Zhuang, L.; Chang, Y. H.
10.1101/2023.02.23.529718 — bioinformatics — Posted on 2023-02-23
737 HilE represses the activity of HilD via a mechanism distinct from that of intestinal long-chain fatty acids.
Joiner, J. D.; Steinchen, W.; Kronenberger, T.; Bange, G.; Wagner, S.; Poso, A.; Hartmann, M. D.
10.1101/2023.02.23.529715 — biochemistry — Posted on 2023-02-23
740 Duplex Sequencing Provides Detailed Characterization of Mutation Frequencies and Spectra in the Bone Marrow of MutaMouse Males Exposed to Procarbazine Hydrochloride
Dodge, A. E.; LeBlanc, D. P.; Zhou, G.; Williams, A.; Meier, M.; Van, P.; Lo, F. Y.; Valentine, C. C.; Salk, J. J.; Yauk, C. L.; Marchetti, F.
10.1101/2023.02.23.529719 — genomics — Posted on 2023-02-23
741 Pleiotropic contribution of rbfox1 to psychiatric and neurodevelopmental phenotypes in a zebrafish model
Anton-Galindo, E.; Adel, M.; Garcia-Gonzalez, J.; Leggieri, A.; Lopez-Blanch, L.; Irimia, M.; Norton, W. H.; Brennan, C. H.; Fernandez-Castillo, N.; Cormand, B.
10.1101/2023.02.23.529711 — genetics — Posted on 2023-02-23
742 MAP9/MAPH-9 supports axonemal microtubule doublets and modulates motor movement
Tran, M. V.; Ferguson, J. W.; Cote, L. E.; Khuntsariya, D.; Fetter, R. D.; Wang, J. T.; Wellard, S. R.; Sallee, M. D.; Eskinazi, S.; Genova, M.; Magiera, M. M.; Janke, C.; Stearns, T.; Lansky, Z.; Shen, K.; Magescas, J.; Feldman, J. L.
10.1101/2023.02.23.529616 — cell biology — Posted on 2023-02-23
743 Luminescence-based screening for extracellular vesicle release modulators reveals a role for PI4KIIIβ in exosome biogenesis upon lysosome inhibition
Bebelman, M. P.; Crudden, C.; Snieder, B.; Thanou, E.; Langedijk, C. J. M.; Viola, M.; Eleonora, S.; Baginska, U.; Cotugno, O.; Bebelman, J. P. M.; van Eijndhoven, M. A. J.; Bosch, L.; Li, K. W.; Smit, M. J.; van Niel, G.; Smit, A. B.; Verweij, F. J.; Pegtel, D. M.
10.1101/2023.02.23.529257 — cell biology — Posted on 2023-02-23
744 Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis
Parveen, S.; Shen, J.; Lun, S.; Zhao, L.; Koleske, B.; Leone, R. D.; Rais, R.; Powell, J. D.; Murphy, J. R.; Slusher, B. S.; Bishai, W. R.
10.1101/2023.02.23.529704 — microbiology — Posted on 2023-02-23
747 Chemogenetic activation of corticotropin-releasing factor-expressing neurons in the anterior bed nucleus of the stria terminalis reduces effortful motivation behaviors
Maita, I.; Bazer, A.; Chae, K.; Parida, A.; Mirza, M.; Sucher, J.; Phan, M.; Liu, T.; Hu, P.; Soni, R.; Roepke, T. A.; Samuels, B. A.
10.1101/2023.02.23.529717 — neuroscience — Posted on 2023-02-23
752 Indigenous cattle of Sri Lanka: Genetic and phylogeographic relationship with Zebu of Indus valley and South Indian origin
LGS, L.; Wickramasinghe, S.; P.A.B.D, A.; Abbas, K.; Hussain, T.; Ramasamy, S.; Manomohan, V.; Tapsoba, A. S. R.; Pichler, R.; Babar, M. E.; Periasamy, K.
10.1101/2023.02.23.529662 — genetics — Posted on 2023-02-23
754 MicroRNA-195-3p as a potential regulator of hypoxic injury in HUVECs
Zhang, W.; Liu, B.; Wang, Y.; Sun, L.; Liu, C.; Zhang, H.; Qin, W.; Liu, J.; Han, L.; Cui, Z.; Shan, W.
10.1101/2023.02.23.529661 — cell biology — Posted on 2023-02-23
756 Influence of HIV-1 genomic RNA on the formation of Gagbiomolecular condensates
Monette, A.; Niu, M.; Maldonado, R. K.; Chang, J.; Lambert, G. S.; Flanagan, J. M.; Cochrane, A. W.; Parent, L. J.; Mouland, A.
10.1101/2023.02.23.529585 — microbiology — Posted on 2023-02-23
757 Spatial transcriptomics maps molecular and cellular requirements for CD4+ T cell-dependent immunity to malaria.
Williams, C. G.; Moreira, M. d. L.; Asatsuma, T.; Skinner, O. P.; Lee, H. J.; Li, S.; Barrera, I.; Murray, E.; Soon, M. S. F.; Engel, J. A.; Khoury, D. S.; Asad, S.; Steiner, T. M.; Joseph, R.; Alexandre, Y.; Mueller, S.; Chen, F.; Haque, A.
10.1101/2023.02.23.529309 — immunology — Posted on 2023-02-23
759 A novel adjuvant formulation induces robust Th1/Th17 memory and mucosal recall responses in Non-Human Primates
Woodworth, J. S.; Contreras, V.; Christensen, D.; Naninck, T.; Kahlaoui, N.; Gallouët, A.-s.; Langlois, S.; Burban, E.; Joly, C.; Gros, W.; Bosquet, N.; Morin, J.; Olsen, M. L.; Rosenkrands, I.; Stein, A.-K.; Wood, G.; Follmann, F.; Lindenstrom, T.; Le Grand, R.; Pedersen, G. K.; Mortensen, R.
10.1101/2023.02.23.529651 — immunology — Posted on 2023-02-23
761 Peak performance singing requires daily vocal exercise in songbirds
Adam, I.; Riebel, K.; Stal, P.; Wood, N. B.; Previs, M. J.; Elemans, C. P.
10.1101/2023.02.23.529633 — neuroscience — Posted on 2023-02-23
770 Energy Coupling and Stoichiometry of Zn2+/H+ Antiport by the Cation Diffusion Facilitator YiiP
Hussein, A.; Fan, S.; Lopez-Redondo, M. L.; Kenney, I.; Zhang, X.; Beckstein, O.; Stokes, D. L.
10.1101/2023.02.23.529644 — biophysics — Posted on 2023-02-23
776 Effects of ploidy and genetic diversity on competitive outcomes.
Perez-Romero, J. A.; Garcia-Munoz, A.; Olivieri, E.; Munoz-Pajares, A. J.; Abdelaziz, M.; Godoy, O.
10.1101/2023.02.23.529645 — ecology — Posted on 2023-02-23
777 The structural mechanism of MCIA complex assembly links mitochondrial redox pathways
McGregor, L.; Acajjaoui, S.; Desfosses, A.; Saidi, M.; Bacia-Verloop, M.; Schwarz, J. J.; Juyoux, P.; von Velsen, J.; Bowler, M. W.; McCarthy, A.; Kandiah, E.; Leonard, G.; Gutsche, I.; Soler Lopez, M.
10.1101/2023.02.23.529646 — molecular biology — Posted on 2023-02-23
782 Reduced serotonergic transmission alters sensitivity to cost and reward via 5-HT1A and 5-HT1B receptors in monkeys
Hori, Y.; Mimura, K.; Nagai, Y.; Hori, Y.; Kumata, K.; Zhang, M.-R.; Suhara, T.; Higuchi, M.; Minamimoto, T.
10.1101/2023.02.23.529630 — neuroscience — Posted on 2023-02-23
783 Broadly effective ACE2 decoy proteins protect mice from lethal SARS-CoV-2 infection
Lu, M.; Yao, W.; Li, Y.; Ma, D.; Zhang, Z.; Wang, H.; Tang, X.; Wang, Y.; Li, C.; Cheng, D.; Lin, H.; Yin, Y.; Zhao, J.; Zhong, G.
10.1101/2023.02.22.529625 — microbiology — Posted on 2023-02-23
786 Cell-cycle status of male and female gametes during Arabidopsis reproduction
Voichek, Y.; Hurieva, B.; Michaud, C.; Schmücker, A.; Vergara, Z.; Desvoyes, B.; Gutierrez, C.; Nizhynska, V.; Jaegle, B.; Borg, M.; Berger, F.; Nordborg, M.; Ingouff, M.
10.1101/2023.02.22.529524 — plant biology — Posted on 2023-02-23
791 Retrieved Sequence Augmentation for Protein Representation Learning
Ma, C.; Zhao, H.; Zheng, L.; Xin, J.; Li, Q.; Wu, L.; Deng, Z.; Lu, Y.; Liu, Q.; Kong, L.
10.1101/2023.02.22.529597 — bioinformatics — Posted on 2023-02-23
792 The impacts of contemporary logging after 250 years of deforestation and degradation on forest-dependent threatened species
Ward, M.; Ashman, K.; Lindenmayer, D.; Legge, S.; Kindler, G.; Cadman, T.; Fletcher, R.; Whiterod, N.; Lintermans, M.; Zylstra, P.; Stewart, R.; Thomas, H.; Blanch, S.; Watson, J.
10.1101/2023.02.22.529603 — ecology — Posted on 2023-02-23
796 Establishing the Validity of Compressed Sensing Diffusion Spectrum Imaging
Radhakrishnan, H.; Zhao, C.; Sydnor, V. J.; Baller, E. B.; Cook, P. A.; Fair, D.; Giesbrecht, B.; Larsen, B.; Murtha, K.; Roalf, D. R.; Rush-Goebel, S.; Shinohara, R.; Shou, H.; Tisdall, M. D.; Vettel, J.; Grafton, S.; Cieslak, M.; Satterthwaite, T.
10.1101/2023.02.22.529546 — neuroscience — Posted on 2023-02-23
797 Transkingdom Network Analysis (TkNA): a systems approach inferring causal factors underlying host-microbiota interactions.
Newman, N. K.; Macovsky, M. S.; Rodrigues, R. R.; Bruce, A. M.; Pederson, J. W.; Patil, S. S.; Padiadpu, J.; Dzutsev, A. K.; Shulzhenko, N.; Trinchieri, G.; Brown, K. S.; Morgun, A.
10.1101/2023.02.22.529449 — systems biology — Posted on 2023-02-23
799 Differential roles of extracellular matrix proteins on primary and metastatic pancreatic cancer cells
Usman, O. H.; Kumar, S.; Walker, R. R.; Xie, G.; Jalil, A. R.; Ramakrishnan, S.; Dooling, L. J.; Wang, Y. J.; Irianto, J.
10.1101/2022.11.11.516201 — cancer biology — Posted on 2023-02-23
800 Arsenic is a potent co-mutagen of ultraviolet light
Speer, R. M.; Nandi, S. P.; Cooper, K. L.; Zhou, X.; Yu, H.; Guo, Y.; Hudson, L. G.; Alexandrov, L. B.; Liu, K. J.
10.1101/2023.02.22.529578 — cancer biology — Posted on 2023-02-23
801 A cell state specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma
Banu, M. A.; Dovas, A.; Argenziano, M. G.; Zhao, W.; Cuervo, H.; Higgins, D. M.; Sperring, C. P.; Pereira, B.; Ye, L. F.; Mahajan, A.; Humala, N.; Furnari, J. L.; Upadhyayula, P. S.; Zandkarimi, F.; Nguyen, T. T.; Wu, P. B.; Hai, L.; Karan, C.; Razavilar, A.; Siegelin, M. D.; Kitajewski, J.; Bruce, J. N.; Stockwell, B. R.; Sims, P. A.; Canoll, P. D.
10.1101/2023.02.22.529581 — cancer biology — Posted on 2023-02-23
802 Pacybara: Accurate long-read sequencing for barcoded mutagenized allelic libraries
Weile, J.; Cote, A. G.; Kishore, N.; Tabet, D.; van Loggerenberg, W.; Rayhan, A.; Roth, F. P.
10.1101/2023.02.22.529427 — bioinformatics — Posted on 2023-02-23
810 Investigating a Gulf Stream Frontal Eddy North of Cape Hatteras: Questioning Overall Impacts on Ecology
Gray, P. C.; Gronniger, J.; Savelyev, I.; Dale, J.; Niebergall, A. K.; Cassar, N.; Windle, A. E.; Hunt, D. E.; Johnson, Z.; Levy, M.; Taylor, C.; Bourdin, G.; Blawas, A.; Lohmann, A.; Silsbe, G.; Johnston, D. W.
10.1101/2023.02.22.529409 — ecology — Posted on 2023-02-23
811 TCAB1 prevents nucleolar accumulation of the telomerase RNA to promote telomerase assembly
Al-Masraf, B. S.; Perez, G. I.; Patrick, E. M.; Adams-Boone, K.; Cohen, S. B.; Han, L.; Yu, K.; Schmidt, J. C.
10.1101/2021.05.27.445986 — cell biology — Posted on 2023-02-23
813 The immune regulation and epidemiological consequences of immune priming in Drosophila
Prakash, A.; Fenner, F.; Shit, B.; Salminen, T. S.; Monteith, K. M.; Khan, I.; Vale, P. F.
10.1101/2023.02.22.529244 — immunology — Posted on 2023-02-23
815 In-silico testing of new pharmacology for restoring inhibition and human cortical function in depression
Guet-McCreight, A.; Moradi-Chameh, H.; Mazza, F.; Prevot, T. D.; Valiante, T. A.; Sibille, E.; Hay, E.
10.1101/2023.02.22.529541 — neuroscience — Posted on 2023-02-23
816 IRF7 impacts on prostate cancer cell survival in response to radiation
Pickard, A.; Amoroso, F.; McCulloch, K.; Erickson, A.; Sachdeva, A.; Steele, R.; Mukherjee, D.; Dellett, M.; McComb, J.; McCaffrey, L.; Hart, C.; Brown, M.; McDade, S. S.; Waugh, D.; Clarke, N.; Butterworth, K.; Illidge, T.; Mirtti, T.; Overton, I. M.; Mills, I.
10.1101/2022.09.23.509205 — cancer biology — Posted on 2023-02-23
817 Metastatic potential in clonal melanoma cells is driven by a rare, early-invading subpopulation
Kaur, A.; Cuenca, L.; Kiani, K.; Busch, G.; Fingerman, D.; Dunagin, M. C.; Li, J.; Dardani, I.; Sanford, E. M.; Pemberton, J.; Goyal, Y.; Weeraratna, A. T.; Herlyn, M.; Raj, A.
10.1101/2022.04.17.488591 — cancer biology — Posted on 2023-02-23
818 Unambiguous detection of SARS-CoV-2 subgenomic mRNAs with single cell RNA sequencing
Cohen, P.; DeGrace, E. J.; Danziger, O.; Patel, R.; Barrall, E. A.; Bobrowski, T.; Kehrer, T.; Cupic, A.; Miorin, L.; Garcia-Sastre, A.; Rosenberg, B. R.
10.1101/2021.11.22.469642 — microbiology — Posted on 2023-02-23
821 TF-Prioritizer: a java pipeline to prioritize condition-specific transcription factors
Hoffmann, M.; Trummer, N.; Schwartz, L.; Jankowski, J.; Lee, H. K.; Willruth, L.-L.; Yuan, K.; Lazareva, O.; Baumgarten, N.; Schmidt, F.; Baumbach, J.; Schulz, M. H.; Blumenthal, D. B.; Hennighausen, L.; List, M.
10.1101/2022.10.19.512881 — bioinformatics — Posted on 2023-02-23
823 Kidney pathology alters cell-clustering in single cell RNA sequencing
Ma, L.; Murea, M.; Choi, Y. A.; Hemal, A. K.; Mikhailov, A. V.; Snipes, J. A.; Chou, J. W.; Langefeld, R. C.; Cui, W.; Miller, L. D.; Hawkins, G. A.; Palmer, N. D.; Langefeld, C. D.; Freedman, B. I.
10.1101/2021.10.08.463030 — cell biology — Posted on 2023-02-23
828 Human IAPP is a contributor to painful diabetic peripheral neuropathy
Albariqi, M. M. H.; Versteeg, S.; Brakkee, E. M.; Coert, J. H.; Elenbaas, B. O. W.; Prado, J.; Hack, C. E.; Hoppener, J. W. M.; Eijkelkamp, N.
10.1101/2021.12.03.471098 — neuroscience — Posted on 2023-02-23
829 The Reissner fiber under tension in vivo shows dynamic interaction with ciliated cells contacting the cerebrospinal fluid
Bellegarda, C.; Zavard, G.; Moisan, L.; Gray, R. S.; Brochard-Wyart, F.; Joanny, J.-F.; Cantaut-Belarif, Y.; Wyart, C.
10.1101/2023.02.22.529498 — biophysics — Posted on 2023-02-23
833 Inducible mismatch repair streamlines forward genetic approaches to target identification of cytotoxic small molecules
Nguyen, T. P.; Fang, M.; Kim, J.; Wang, B.; Lin, E.; Khivansara, V.; Barrows, N.; Rivera-Cancel, G.; Goralski, M.; Cervantes, C. L.; Xie, S.; Peterson, J. M.; Povedano, J. M.; Antczak, M. I.; Posner, B. A.; McFadden, D. G.; Ready, J. M.; De Brabander, J.; Nijhawan, D.
10.1101/2023.02.21.529401 — biochemistry — Posted on 2023-02-23
834 GenBank genomics highlight the genomic features, genetic diversity and regulation of morphological, metabolic and disease-resistance traits in Nicotiana tabacum
Zan, Y.; Chen, S.; Ren, M.; Liu, G.; Liu, Y.; Si, H.; Liu, Z.; Liu, D.; Zhang, X.; Tong, Y.; Li, Y.; Jiang, C.; Wen, L.; Xiao, Z.; Sun, Y.; Geng, R.; Feng, Q.; Wang, Y.; Chen, Y.; Cheng, L.; Yang, A.
10.1101/2023.02.21.529366 — genetics — Posted on 2023-02-23
837 Fetal liver macrophages contribute to the hematopoietic stem cell niche by controlling granulopoiesis
Kayvanjoo, A. H.; Splichalova, I.; Bejarano, D. A.; Huang, H.; Mauel, K.; Makdissi, N.; Heider, D.; Balzer, N. R.; Osei-Sarpong, C.; Bassler, K.; Schultze, J.; Uderhardt, S.; Kiermaier, E.; Beyer, M.; Schlitzer, A.; Mass, E.
10.1101/2023.02.21.529403 — developmental biology — Posted on 2023-02-23
838 σ28-dependent small RNA regulation of flagella biosynthesis
Melamed, S.; Zhang, A.; Jarnik, M.; Mills, J.; Silverman, A.; Zhang, H.; Storz, G.
10.1101/2021.08.05.455139 — microbiology — Posted on 2023-02-23
840 A Latent Clinical-anatomical Dimension Relating Metabolic Syndrome to Brain Morphology - Evidence from a Multivariate Imaging Analysis of 40,087 Individuals
Petersen, M.; Hoffstaedter, F.; Naegele, F. L.; Mayer, C.; Schell, M.; Rimmele, D. L.; Zyriax, B.-C.; Zeller, T.; Kuehn, S.; Gallinat, J.; Fiehler, J.; Twerenbold, R.; Omidvarnia, A.; Patil, K.; Eickhoff, S. B.; Thomalla, G.; Cheng, B.
10.1101/2023.02.22.529531 — neuroscience — Posted on 2023-02-23
844 Purification of Human β and γ-actin from Budding Yeast
Haarer, B. K.; Pimm, M. L.; deJong, E. P.; Henty-Ridilla, J. L.; Amberg, D.
10.1101/2022.08.17.504301 — biochemistry — Posted on 2023-02-22
845 Auditory feedback-independent maintenance of song performance through daily singing in adult songbirds
Mizuguchi, D.; Sanchez-Valpuesta, M.; Kim, Y.; dos Santos, E. B.; Kang, H.; Mori, C.; Wada, K.; Kojima, S.
10.1101/2023.02.22.529516 — animal behavior and cognition — Posted on 2023-02-22
846 Tocilizumab treatment leads to early resolution of lymphopenia and myeloid dysregulation in patients hospitalized with COVID-19
Shivram, H.; Hackney, J. A.; Rosenberger, C. M.; Teterina, A.; Qamra, A.; Onabajo, O.; McBride, J.; Cai, F.; Bao, M.; Tsai, L.; Regev, A.; Rosas, I.; Bauer, R.
10.1101/2022.10.27.514096 — immunology — Posted on 2023-02-22
847 Dentate neurogenesis mediates cognitive flexibility via modulation of the hippocampal longitudinal-axis network
Li, H.; Tamura, R.; Hayashi, D.; Asai, H.; Koga, J.; Ando, S.; Yokota, S.; Kaneko, J.; Sakurai, K.; Sumiyoshi, A.; Yamamoto, T.; Hikishima, K.; Tanaka, K. Z.; McHugh, T.; Hisatsune, T.
10.1101/2023.02.22.529526 — neuroscience — Posted on 2023-02-22
850 Exploring dose-response relationships in Aedes aegypti survival upon bacteria and arbovirus infection.
Rocha, M. M.; Talyuli, O. A. C.; Costa, C. L. R.; Granella, L. W.; Mansur, D. S.; Oliveira, P. L.; Oliveira, J. H. M.
10.1101/2022.09.29.510144 — microbiology — Posted on 2023-02-22
852 A Comparison of fMRI Data-Derived and Physiological Data-Derived Methods for Physiological Noise Correction
Krentz, M.; Tutunji, R.; Kogias, N.; Mahadevan, H. M.; Reppmann, Z.; Krause, F.; Hermans, E. J.
10.1101/2023.02.22.529506 — neuroscience — Posted on 2023-02-22
853 Mitochondrial phosphagen kinases support the volatile power demands of motor nerve terminals
Justs, K. A.; Sempertegui, S.; Riboul, D. V.; Oliva, C. D.; Durbin, R. J.; Crill, S.; Su, C.; Renden, R. B.; Fily, Y.; Macleod, G. T.
10.1101/2022.12.21.521290 — neuroscience — Posted on 2023-02-22
854 A new look at the architecture and dynamics of the Hydra nerve net
Keramidioti, A.; Schneid, S.; Busse, C.; Cramer von Laue, C.; Bertulat, B.; Salvenmoser, W.; Hess, M.; Alexandrova, O.; Glauber, K.; Steele, R.; Hobmayer, B.; Holstein, T. W.; David, C. N.
10.1101/2023.02.22.529525 — neuroscience — Posted on 2023-02-22
855 A Latent Clinical-anatomical Dimension Relating Metabolic Syndrome to Brain Morphology - Evidence from a Multivariate Imaging Analysis of 40,087 Individuals
Petersen, M.; Hoffstaedter, F.; Naegele, F. L.; Mayer, C.; Schell, M.; Rimmele, D. L.; Zyriax, B.-C.; Zeller, T.; Kuehn, S.; Gallinat, J.; Fiehler, J.; Twerenbold, R.; Omidvarnia, A.; Patil, K.; Eickhoff, S. B.; Thomalla, G.; Cheng, B.
10.1101/2023.02.22.529531 — neuroscience — Posted on 2023-02-22
856 Induction of PARP7 Creates a Vulnerability for Growth Inhibition by RBN2397 in Prostate Cancer Cells
YANG, C.; Wierbilowicz, K.; Dworak, N. M.; Bae, S. Y.; Tengse, S. B.; Abianeh, N.; Drake, J.; Abbas, T.; Ratan, A.; Wotton, D.; Paschal, B. M.
10.1101/2022.09.02.506406 — cancer biology — Posted on 2023-02-22
857 CXCR2 expression during melanoma tumorigenesis controls transcriptional programs that facilitate tumor growth
Yang, J.; Bergdorf, K.; Yan, C.; Luo, W.; Chen, S.-C.; Ayers, D.; Liu, Q.; Liu, X.; Boothby, M. R.; Groves, S. M.; Oleskie, A.; Zhang, X.; Maeda, D.; Zebala, J.; Quaranta, V.; Richmond, A.
10.1101/2023.02.22.529548 — cancer biology — Posted on 2023-02-22
858 Acquired resistance to PD-L1 inhibition is associated with an enhanced type I IFN-stimulated secretory program in tumor cells
Shi, Y.; Dolan, M.; Mastri, M.; McKenery, A.; Hill, J. W.; Dommer, A.; Benzekry, S.; Long, M.; Abrams, S.; Puzanov, I.; Ebos, J. M. L.
10.1101/2021.07.01.450417 — cancer biology — Posted on 2023-02-22
859 A consensus score to combine inferences from multiple centres
Haselimashhadi, H.; Babalola, K.; Wilson, R.; Groza, T.; Munoz-Fuentes, V.
10.1101/2022.11.10.515944 — bioinformatics — Posted on 2023-02-22
860 Motile Living Biobots Self-Construct from Adult Human Somatic Progenitor Seed Cells
Gumuskaya, G.; Srivastava, P.; Cooper, B. G.; Lesser, H.; Semegran, B.; Garnier, S.; Levin, M.
10.1101/2022.08.04.502707 — bioengineering — Posted on 2023-02-22
862 ROBUST AND EFFICIENT ACTIVE GENETICS GENE CONVERSION IN THE RAT AND MOUSE
Lai, C.; Alvarez, O.; Read, K.; van Fossan, D.; Conner, C. M.; Xu, S. X.-R.; Cowley, D. O.; Gantz, V.; Webb, D. R.; Jarnagin, K.
10.1101/2022.08.30.505951 — genetics — Posted on 2023-02-22
864 Joint testing of rare variant burden scores using non-negative least squares
Ziyatdinov, A.; Mbatchou, J.; Marcketta, A.; Backman, J.; Gaynor, S.; Zou, Y.; Joseph, T.; Geraghty, B.; Herman, J.; Watanabe, K.; Ghosh, A.; Kosmicki, J.; Locke, A.; Regeneron Genetics Center, ; Thornton, T.; Kang, H. M.; Ferreira, M.; Baras, A.; Abecasis, G.; Marchini, J.
10.1101/2023.02.22.529560 — genetics — Posted on 2023-02-22
865 Novel Methods for Multi-ancestry Polygenic Prediction and their Evaluations in 5.1 Million Individuals of Diverse Ancestry
Zhang, H.; Zhan, J.; Jin, J.; Zhang, J.; Lu, W.; Zhao, R.; Ahearn, T. U.; Yu, Z.; O'Connell, J.; Jiang, Y.; Chen, T.; Okuhara, D.; 23andMe Research Team, ; Garcia-Closas, M.; Lin, X.; Koelsch, B. L.; Chatterjee, N.
10.1101/2022.03.24.485519 — genetics — Posted on 2023-02-22
866 Transgenerational exposure to deoxygenation and warming disrupts mate-detection in Gammarus locusta
Pereira, B. P.; Neff, S.; Borges, F. O.; Otjacques, E.; Barreto, G.; Ranucci, M.; Court, M.; Rosa, R.; Repolho, T. F.; Paula, J. R.
10.1101/2023.02.21.529266 — ecology — Posted on 2023-02-22
868 Gamma-interferon-inducible lysosomal thiol reductase maintains cardiac immuno-metabolic homeostasis in heart failure
Li, M.; Wang, J.; Qian, Q.; Chen, B.; Zhang, Z.; Barroso, E.; Zhang, Y.; Hall, D. D.; Abel, E. D.; Song, L.-S.; Yang, L.
10.1101/2022.07.03.498477 — molecular biology — Posted on 2023-02-22
869 Group A Streptococcus Induces Lysosomal Dysfunction in THP-1 Macrophages
Nishioka, S. T.; Snipper, J.; Lee, J.; Schapiro, J.; Zhang, R. Z.; Abe, H.; Till, A.; Okumura, C. Y.
10.1101/2022.06.17.496523 — microbiology — Posted on 2023-02-22
870 The AEGEAN-169 clade of bacterioplankton is synonymous with SAR11 subclade V (HIMB59) and metabolically distinct
Getz, E. W.; Lanclos, V. C.; Kojima, C. Y.; Cheng, C.; Henson, M. W.; Schon, M. E.; Ettema, T. J.; Faircloth, B. C.; Thrash, J. C.
10.1101/2023.02.22.529538 — microbiology — Posted on 2023-02-22
872 Drosophila SPG12 ortholog, reticulon-like 1, governs presynapticER organization and Ca2+ dynamics
Perez-Moreno, J. J.; Smith, R. C.; Oliva, M. K.; Gallo, F.; Ohja, S.; Müller, K.; O'Kane, C. J.
10.1101/2021.12.17.473229 — neuroscience — Posted on 2023-02-22
873 The Queensland Twin Adolescent Brain Project, a longitudinal study of adolescent brain development
Strike, L. T.; Hansell, N. K.; Chuang, K.-H.; Miller, J. L.; de Zubicaray, G. I.; Thompson, P. M.; McMahon, K. L.; Wright, M. J.
10.1101/2022.05.19.492753 — neuroscience — Posted on 2023-02-22
875 Auditory confounds can drive online effects of transcranial ultrasonic stimulation in humans
Kop, B. R.; Shamli Oghli, Y.; Grippe, T. C.; Nandi, T.; Lefkes, J.; Meijer, S. W.; Farboud, S.; Engels, M.; Hamani, M.; Null, M.; Radetz, A.; Hassan, U.; Darmani, G.; Chetverikov, A.; den Ouden, H. E. M.; Bergmann, T. O.; Chen, R.; Verhagen, L.
10.1101/2023.02.22.527901 — neuroscience — Posted on 2023-02-22
877 Ventral premotor cortex influences spinal cord activation during force generation
Braass, H.; Feldheim, J.; Chu, Y.; Tinnermann, A.; Finsterbusch, J.; Büchel, C.; Schulz, R.; Gerloff, C.
10.1101/2023.02.22.529375 — neuroscience — Posted on 2023-02-22
878 DISRUPTION OF SYMPATHETIC OUTFLOW TO INTRA-ABDOMINAL ORGANS EMULATES THE METABOLIC EFFECTS OF SLEEVE GASTRECTOMY IN OBESE MICE
Schwartz, G. J.; Batista, R.; Lopatinsky, N. R.; Kraljevic, M.; Jiang, C.; Dirnberger, A. S.; Emiliano, A.
10.1101/2022.10.17.512615 — neuroscience — Posted on 2023-02-22
880 Structural brain correlates of non-verbal cognitive ability in 5-year-old children: findings from the FinnBrain Birth Cohort study
Pulli, E. P.; Nolvi, S.; Eskola, E.; Nordenswan, E.; Holmberg, E.; Copeland, A.; Kumpulainen, V.; Silver, E.; Merisaari, H.; Saunavaara, J.; Parkkola, R.; Lahdesmaki, T.; Saukko, E.; Kataja, E.-L.; Korja, R.; Karlsson, L.; Karlsson, H.; Tuulari, J. J.
10.1101/2023.02.22.529110 — neuroscience — Posted on 2023-02-22
881 A Novel Memory Type in C. elegans Exhibits Post-Training Consolidation
Merritt, D. M.; Udachina, A.; Freidel, N.; Almeida, S. M. T.; Lau, Y. M. A.; van der Kooy, D.
10.1101/2023.02.22.529281 — neuroscience — Posted on 2023-02-22
883 Glycoproteome remodelling and granule-specific N-glycosylation accompany neutrophil granulopoiesis
Kawahara, R.; Ugonotti, J.; Chatterjee, S.; Tjondro, H. C.; Loke, I.; Parker, B. L.; Venkatakrishnan, V.; Dieckmann, R.; Sumer-Bayraktar, Z.; Karlsson-Bengtsson, A.; Bylund, J.; Thaysen-Andersen, M.
10.1101/2023.01.18.524318 — systems biology — Posted on 2023-02-22
884 Modulation of quantitative trait loci for Arabidopsis thaliana seed performance by the maternal and germination environment.
Snoek, B. L.; Serin, E. A. R.; Nijveen, H.; Willems, L. A. J.; Rienstra, J. A.; van Zanten, M.; Hilhorst, H. W. M.; Ligterink, W.
10.1101/2023.02.22.529582 — plant biology — Posted on 2023-02-22
886 Targeting DNA2 Overcomes Metabolic Reprogramming in Multiple Myeloma
Thongon, N.; Ma, F.; Lockyer, P.; Baran, N.; Liu, J.; Jackson, C.; Rose, A.; Wildeman, B.; Marchesini, M.; Marchica, V.; Storti, P.; Giuliani, N.; Ganan-Gomez, I.; Adema, V.; Qing, Y.; Ha, M.; Fonseca, R.; Class, C.; Tan, L.; Kanagal-Shamanna, R.; Nolasco, D. B.; Cerchione, C.; Montalban-Bravo, G.; Santoni, A.; Bueso-Ramos, C.; Konopleva, M.; Lorenzi, P.; Garcia-Manero, G.; Manasanch, E.; Viale, A.; Chesi, M.; Colla, S.
10.1101/2023.02.22.529457 — cancer biology — Posted on 2023-02-22
887 FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators
Roopnarine, O.; Yuen, S. L.; Thompson, A. R.; Roelike, L. N.; Rebbeck, R. T.; Bidwell, P. A.; Aldrich, C. C.; Cornea, R. L.; Thomas, D. D.
10.1101/2023.02.22.529557 — biophysics — Posted on 2023-02-22
890 Discovery and validation of the binding poses of allosteric fragment hits to PTP1b: From molecular dynamics simulations to X-ray crystallography
Greisman, J. B.; Willmore, L.; Yeh, C. Y.; Giordanetto, F.; Shahamadtar, S.; Nisonoff, H.; Maragakis, P.; Shaw, D. E.
10.1101/2022.11.14.516467 — biophysics — Posted on 2023-02-22
893 Mechanistic insights into the activation of bacterial ExoY nucleotidyl cyclase toxins targeting actin-profilin
Teixeira-Nunes, M.; Retailleau, P.; Raoux-Barbot, D.; Comisso, M.; Missinou, A. A.; Velours, C.; Plancqueel, S.; Ladant, D.; Mechold, U.; Renault, L.
10.1101/2023.01.13.523968 — biochemistry — Posted on 2023-02-22
894 cGLRs are a diverse family of pattern recognition receptors in animal innate immunity
Li, Y.; Slavik, K. M.; Morehouse, B. R.; Mann, C. C. d. O.; Mears, K.; Liu, J.; Kashin, D.; Schwede, F.; Kranzusch, P. J.
10.1101/2023.02.22.529553 — biochemistry — Posted on 2023-02-22
895 Complex chemical signals dictate Ah receptor activation through the gut-lung axis
Dong, F.; Murray, I. A.; Annalora, A.; Coslo, D.; Desai, D.; Gowda, K.; Yang, J.; Wang, D.; Koo, I.; Hao, F.; Amin, S. G.; Patterson, A. D.; Marcus, C.; Perdew, G. H.
10.1101/2023.02.22.529529 — biochemistry — Posted on 2023-02-22
896 Mass Spectrometry Reveals that Oxysterols are Secreted from Non-Alcoholic Fatty Liver Disease Induced Organoids
Komurcu, K. S.; Wilhelmsen, I.; Thorne, J. L.; Krauss, S.; Wilson, S. R.; Aizenshtadt, A.; Roberg-Larsen, H.
10.1101/2023.02.22.529551 — biochemistry — Posted on 2023-02-22
897 Error-corrected Duplex Sequencing enables direct detection and quantification of mutations in human TK6 cells with remarkable inter-laboratory consistency
Cho, E.; Swartz, C. D.; Williams, A.; Rivas, M.; Recio, L.; Witt, K. L.; Schmidt, E. K.; Yaplee, J.; Smith, T.; Van, P.; Lo, F. Y.; Valentine, C. C.; Salk, J. J.; Marchetti, F.; Smith-Roe, S.; Yauk, C.
10.1101/2023.02.22.529418 — genomics — Posted on 2023-02-22
898 A KASP Marker for the Potato Late Blight Resistance Gene RB/Rpi-blb1
Sorensen, P. L.; Christensen, G.; Karki, H. S.; Endelman, J. B.
10.1101/2023.02.22.529539 — genetics — Posted on 2023-02-22
902 Cellular protection from H2O2 toxicity by Fv-Hsp70 and mutants of Fv-Hsp70. Protection via catalase and gamma-glutamyl cysteine synthase.
Hino, C.; Chan, G.; Jordaan, G.; Chang, S. S.; Saunders, J.; Bashir, M. T.; Hansen, J. E.; Gera, J.; Weisbart, R. H.; Nishimura, R. N.
10.1101/2023.02.22.529417 — cell biology — Posted on 2023-02-22
903 Quantifying the idiosyncrasy in brain activations
Nakuci, J.; Yeon, J.; Xue, K.; Kim, J.-H.; Kim, S.-P.; Rahnev, D.
10.1101/2022.08.01.502338 — neuroscience — Posted on 2023-02-22
905 Reinforcement-Based Processes Actively Regulate MotorExploration Along Redundant Solution Manifolds
Roth, A. M.; Calalo, J. A.; Lokesh, R.; Sullivan, S. R.; Grill, S.; Jeka, J. J.; van der Kooij, K.; Carter, M. J.; Cashaback, J. G. A.
10.1101/2023.02.08.527668 — neuroscience — Posted on 2023-02-22
906 Recombinant NAGLU-IGF2 prevents physical and neurological disease and improves survival in Sanfilippo B syndrome
Le, S. Q.; Kan, S.-h.; Roberts, M. S.; Dearborn, J. T.; Wang, F.; LI, S.; Snella, E. N.; Jens, J. K.; Valentine, B. N.; Nelvagal, H. R.; Sorensen, A.; Chintilapati, K.; Ohlemiller, K.; Vogler, C.; Cooper, J. D.; Chou, T.-F.; Ellinwood, N. M.; Smith, J. D.; Sands, M. S.; Dickson, P.
10.1101/2021.08.06.455469 — neuroscience — Posted on 2023-02-22
911 SPA-STOCSY: An Automated Tool for Identification of Annotated and Non-Annotated Metabolites in High-Throughput NMR Spectra
Han, X.; Wang, W.; Ma, L.; Ramahi, I. A.; Botas, J.; MacKenzie, K.; Allen, G. I.; Young, D. W.; Liu, Z.; Maletic-Savatic, M.
10.1101/2023.02.22.529564 — bioinformatics — Posted on 2023-02-22
912 Label-free histological analysis of retrieved thrombi in acute ischemic stroke using optical diffraction tomography and deep learning
Chung, Y.; Kim, G.; Moon, A.-R.; Ryu, D.; Hugonnet, H.; Lee, M. J.; Shin, D.; Lee, S.-J.; Lee, E.-S.; Park, Y.
10.1101/2023.02.22.529519 — bioengineering — Posted on 2023-02-22
914 Seasonal and genetic effects on lipid profiles of juvenile Atlantic salmon
House, A.; Debes, P.; Holopainen, M.; Kakela, R.; Donner, I.; Frapin, M.; Ahi, E. P.; Kurko, J.; Ruhanen, H.; Primmer, C. R.
10.1101/2023.02.22.529528 — evolutionary biology — Posted on 2023-02-22
915 Bayesian inference of toothed whale lifespans
Ellis, S.; Croft, D. P.; Nielsen, M. L. K.; Franks, D. W.; Weiss, M. N.
10.1101/2023.02.22.529527 — evolutionary biology — Posted on 2023-02-22
916 Functional traits shape plant-plant interactions and recruitment in a hotspot of woody plant diversity.
Cooksley, H.; Dreyling, L.; Esler, K. J.; Griebenow, S.; Neumann, G.; Valentine, A.; Schleuning, M.; Schurr, F. M.
10.1101/2023.02.22.529386 — ecology — Posted on 2023-02-22
918 The ATM-E6AP-MASTL axis mediates DNA damage checkpoint recovery
Li, Y.; Wang, F.; Li, X.; Wang, L.; Yang, Z.; You, Z.; Peng, A.
10.1101/2023.02.22.529521 — cell biology — Posted on 2023-02-22
919 Isoform-specific targeting properties of the protocadherin CDHR5 control its apical delivery to promote brush border assembly
Matoo, S.; Graves, M. J.; Choi, M. S.; El Sheikh Idris, R. A.; Acharya, P.; Thapa, G.; Nguyen, T.; Atallah, S. Y.; Tipirneni, A. K.; Stevenson, P. J.; Crawley, S. W.
10.1101/2023.02.22.529570 — cell biology — Posted on 2023-02-22
921 Defining Early Steps in B. subtilis Biofilm Biosynthesis
Arbour, C. A.; Nagar, R.; Bernstein, H. M.; Ghosh, S.; Al-Sammarraie, Y.; Dorfmueller, H. C.; Ferguson, M. A. J.; Stanley-Wall, N.; Imperiali, B.
10.1101/2023.02.22.529487 — microbiology — Posted on 2023-02-22
925 Raspberry plant stress detection using hyperspectral imaging
Williams, D.; Karley, A.; Britten, A.; McCallum, S.; Graham, J.
10.1101/2023.02.22.529512 — plant biology — Posted on 2023-02-22
926 Hydraulic adjustments of Scots pine colonizing a harsh environment on volcano slopes
Barigah, T. S.; Dos Santos Farnese, F.; De Menezes Silva, P. E.; Humbert, P.; Ennajeh, M.; Ngao, J.; Badel, E.; Cochard, H.; Herbette, S.
10.1101/2023.02.22.528520 — plant biology — Posted on 2023-02-22
929 Mucus production, host-microbiome interactions, hormone sensitivity, and innate immune responses modeled in human endo- and ecto-cervix chips
Izadifar, Z.; Cotton, J.; Chen, C.; Bustos, N. A.; Horvath, V.; Stejskalova, A.; Wu, C.; Gulati, A.; LoGrande, N. T.; Doherty, E.; To, T.; Gilpin, S. E.; Sesay, A. M.; Goyal, G.; Ribbeck, K.; Lebrilla, C. B.; Ingber, D. E.
10.1101/2023.02.22.529436 — bioengineering — Posted on 2023-02-22
932 DOCK3 regulates normal skeletal muscle regeneration and glucose metabolism
Samani, A.; Karuppasamy, M.; English, K. G.; Siler, C. A.; Wang, Y.; Widrick, J. J.; Alexander, M. S.
10.1101/2023.02.22.529576 — genetics — Posted on 2023-02-22
934 O-GlcNAcylation regulates neurofilament-light assembly and function and is perturbed by Charcot-Marie-Tooth disease mutations
Huynh, D. T.; Hu, J.; Schneider, J. R.; Tsolova, K. N.; Soderblom, E. J.; Watson, A. J.; Chi, J.-T. A.; Evans, C. S.; Boyce, M.
10.1101/2023.02.22.529563 — cell biology — Posted on 2023-02-22
936 High fat diet ameliorates the mitochondrial cardiomyopathy of CHCHD10 mutant mice
Southwell, N.; Zhao, D.; Sayles, N. M.; Dash, J.; Fujita, K.; D'Aurelio, M.; Manfredi, G.; Kawamata, H.
10.1101/2023.02.22.529577 — molecular biology — Posted on 2023-02-22
938 Inhibition of cleavage of human complement component C5 and the R885H C5 variant by two distinct high affinity anti-C5 nanobodies
Struijf, E. M.; De la O Becerra, K. I.; Ruyken, M.; van Oosterom, F.; Siere, D. Y.; Heesterbeek, D. A. C.; Dolk, E.; Heukers, R.; Bardoel, B. W.; Gros, P.; Rooijakkers, S. H. M.
10.1101/2023.02.22.529391 — immunology — Posted on 2023-02-22
939 Novel Fas-TNFR chimeras that prevents Fas ligand-mediated kill and signals synergistically to enhance CAR T-cell efficacy
McKenzie, C.; El-Kholy, M.; Parekh, F.; Robson, M.; Lamb, K.; Allen, C.; Sillibourne, J.; Cordoba, S.; Thomas, S.; Pule, M.
10.1101/2023.02.22.529492 — synthetic biology — Posted on 2023-02-22
940 Air channels create a directional light signal to regulate hypocotyl phototropism
Nawkar, G. M.; Martina, L.; Goyal, A.; Schmid-Siegert, E.; Fleury, J.; Mucciolo, A.; De Bellis, D.; Schueler, A.; Fankhauser, C.
10.1101/2023.02.22.529488 — plant biology — Posted on 2023-02-22
941 The balance between growth and resistance is shifted to the latter by overaccumulation of chloroplast-nucleus located WHIRLY1 in barley
Saeid Nia, M.; Frank, S.; Schaefer, A.; Desel, C.; Mulisch, M.; Voigt, U.; Nowara, D.; Tandron Moya, Y. A.; Bilger, W.; Wiren, N. v.; Hensel, G.; Krupinska, K.
10.1101/2023.02.22.529264 — plant biology — Posted on 2023-02-22
949 The gut lactic acid bacteria metabolite, 10-oxo-cis-6,trans-11-octadecadienoic acid, suppresses inflammatory bowel disease in mice by modulating the NRF2 pathway and GPCR-signaling
Ando, M.; Nagata, K.; Ito, N.; Noguchi, S.; Yamamoto, A.; Kodama, N.; Yashiro, T.; Hachisu, M.; Ichihara, G.; Kishino, S.; Yamamoto, M.; Ogawa, J.; Nishiyama, C.
10.1101/2023.02.22.529495 — immunology — Posted on 2023-02-22
953 The oncogenic role of Streptococcus gallolyticus subsp. gallolyticus is linked to activation of multiple cancer-related signaling pathways
Pasquereau-Kotula, E.; Nigro, G.; Dingli, F.; Loew, D.; Poullet, P.; Xu, Y.; Kopetz, S.; Davis, J.; Peduto, L.; Robbe-Masselot, C.; Sansonetti, P.; Trieu-Cuot, P.; Dramsi, S.
10.1101/2023.02.17.528913 — microbiology — Posted on 2023-02-22
957 Differentially Expressed Heterogeneous Overdispersion Genes Testing for Count Data
Yuan, Y.; Xu, Q.; Wani, A.; Dahrendorff, J.; Wang, C.; Donglasan, J.; Burgan, S.; Graham, Z.; Uddin, M.; Wildman, D.; Qu, A.
10.1101/2023.02.21.529455 — genomics — Posted on 2023-02-22
959 Increased birth rank of homosexual males: disentangling the older brother effect and sexual antagonism hypothesis
Raymond, M.; Turek, D.; Durand, V.; Nila, S.; Suryobroto, B.; Vadez, J.; Barthes, J.; Apostolou, M.; Crochet, P.-A.
10.1101/2022.02.22.481477 — evolutionary biology — Posted on 2023-02-22
960 Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization
Berquez, M.; Chen, Z.; Festa, B. P.; Krohn, P.; Keller, S. A.; Parolo, S.; Korzinkin, M.; Gaponova, A.; Laczko, E.; Domenici, E.; Devuyst, O.; Luciani, A.
10.1101/2022.08.28.505580 — cell biology — Posted on 2023-02-22
961 Life stage and vaccination shape the gut microbiome of hatchery-reared Atlantic salmon (Salmo salar)
Andres, K. J.; Liu, B.; Johnson, L. E.; Kapuscinski, K. L.; Moerke, A. H.; Ling, F.; Knouft, J. H.
10.1101/2023.02.21.529474 — microbiology — Posted on 2023-02-22
964 Alcohol Drinking Alters Stress Response to Predator Odor via Extended Amygdala Kappa Opioid Receptor Signaling in Male Mice
Hwa, L. S.; Neira, S.; Flanigan, M. E.; Stanhope, C. M.; Pina, M. M.; Pati, D. S.; Hon, O. J.; Yu, W.; Kokush, E.; Calloway, R.; Boyt, K.; Kash, T. L.
10.1101/773481 — neuroscience — Posted on 2023-02-22
965 Top-down specific preparatory activations for Selective Attention and Perceptual Expectations
G. Penalver, J. M.; Lopez-Garcia, D.; Gonzalez-Garcia, C.; Aguado-Lopez, B.; Gorriz, J. M.; Ruz, M.
10.1101/2022.09.13.507583 — neuroscience — Posted on 2023-02-22
966 FitMultiCell: Simulating and parameterizing computational models of multi-scale and multi-cellular processes
Alamoudi, E.; Schälte, Y.; Müller, R.; Starruss, J.; Bundgaard, N.; Graw, F.; Brusch, L.; Hasenauer, J.
10.1101/2023.02.21.528946 — systems biology — Posted on 2023-02-22
967 Discovery and characterization of a chemical probe targeting the zinc-finger ubiquitin-binding domain of HDAC6
Harding, R. J.; Franzoni, I.; Mann, M. K.; Szewczyk, M.; Mirabi, B.; Owens, D. D.; Ackloo, S.; Scheremetjew, A.; Juarez-Ornelas, K. A.; Sanichar, R.; Baker, R. J.; Dank, C.; Brown, P. J.; Barsyte-Lovejoy, D.; Santhakumar, V.; Schapira, M.; Lautens, M.; Arrowsmith, C. H.
10.1101/2023.02.21.525740 — pharmacology and toxicology — Posted on 2023-02-22
968 Augmentation of Histone Deacetylase 6 Activity Impairs Mitochondrial Respiratory Complex I in Ischemic/Reperfused Diabetic Hearts
Ge, Z.-D.; Baumgardt, S. L.; Fang, J.; Fu, X.; Liu, Y.; Xia, Z.; Zhao, M.; Chen, L.; Mishra, R.; Gunasekaran, M.; Saha, P.; Forbess, J. M.; Bosnjak, Z. J.; Camara, A. K. S.; Kersten, J.; Thorp, E. B.; Kaushal, S.
10.1101/2023.02.21.529462 — pharmacology and toxicology — Posted on 2023-02-22
969 In Vitro Antibacterial Activity of Dinuclear Thiolato-Bridged Ruthenium(II)-Arene Compounds
Bugnon, Q.; Melendez, C.; Desiatkina, O.; Fayolles Chorus de Chaptes, L.; Holzer, I.; Emilia, P.; Hilty, M.; Furrer, J.
10.1101/2023.02.21.529477 — pharmacology and toxicology — Posted on 2023-02-22
970 Ketosis Prevents Abdominal Aortic Aneurysm Rupture Through CCR2 Downregulation and Enhanced MMP Balance
Sastriques-Dunlop, S.; Elizondo-Benedetto, S.; Arif, B.; Meade, R.; Zaghloul, M. S.; Luehmann, H.; Heo, G. S.; English, S. J.; Liu, Y.; Zayed, M. A.
10.1101/2023.02.21.529460 — pathology — Posted on 2023-02-22
972 Design, evaluation and implementation of synthetic isopentyldiol pathways in Escherichia coli
Liu, Y.; Chen, L.; Liu, P.; Yuan, Q.; Ma, C.; Wang, W.; Zhang, C.; Ma, H.; Zeng, A.-P.
10.1101/2023.02.21.529368 — bioengineering — Posted on 2023-02-22
973 Ubiquinone deficiency drives reverse electron transport to disrupt hepatic metabolic homeostasis in obesity
Goncalves, R. L. S.; Wang, Z. B.; Inouye, K. E.; Lee, Y. G.; Fu, X.; Saksi, J.; Rosique, C.; Parlakgul, G.; Arruda, A. P.; Hui, T. S.; Loperena, M. C.; Burgess, S. C.; Graupera, I.; Hotamisligil, G. S.
10.1101/2023.02.21.528863 — biochemistry — Posted on 2023-02-22
974 Machined silicon traps for capturing novel bacterial communities and strains in-situ
Romero Santiveri, C.; Vineis, J. H.; Martins, S.; Calaza, C.; Gaspar, J.; Bowen, J. L.; Goluch, E. D.
10.1101/2023.02.21.529475 — microbiology — Posted on 2023-02-22
975 Endogenous bystander killing mechanisms enhance the activity of novel FAP-CAR-T cells against glioblastoma
Yu, W.; Ebert, L. M.; Truong, N. T.; Polara, R.; He, K. K.; Gargett, T.; Yeo, E. C.; Brown, M. P.
10.1101/2023.02.21.529331 — immunology — Posted on 2023-02-22
976 Manipulating single-unit theta phase-locking with PhaSER: An open-source tool for real-time phase estimation and manipulation
Wick, Z. C.; Philipsberg, P. A.; Lamsifer, S. I.; Kohler, C.; Katanov, E.; Feng, Y.; Humphrey, C.; Shuman, T.
10.1101/2023.02.21.529420 — neuroscience — Posted on 2023-02-22
977 Revealing the combined roles of Abeta and tau in Alzheimer's disease via a pathophysiological activity decoder
Sanchez-Rodriguez, L. M.; Bezgin, G.; Carbonell, F.; Therriault, J.; Fernandez-Arias, J.; Karikari, T. K. M.; Ashton, N. J.; Benedet, A.; Zetterberg, H.; Blennow, K.; Triana-Baltzer, G.; Kolb, H. C.; Rosa-Neto, P.; Iturria-Medina, Y.
10.1101/2023.02.21.529377 — neuroscience — Posted on 2023-02-22
978 Myomatrix arrays for high-definition muscle recording
Chung, B.; Zia, M.; Thomas, K.; Michaels, J. A.; Jacob, A.; Pack, A.; Williams, M.; Nagapudi, K.; Teng, L. H.; Arrambide, E.; Ouellette, L.; Oey, N.; Gibbs, R.; Anschutz, P.; Lu, J.; Wu, Y.; Kashefi, M.; Oya, T.; Kersten, R.; Mosberger, A. C.; O`Connell, S.; Wang, R.; Marques, H. G.; P. Mendes, A. R.; Lenschow, C.; Kondakath, G.; Kim, J. J.; Olson, W.; Quinn, K.; Perkins, P.; Gatto, G.; Thanawalla, A. R.; Coltman, S. K.; Kim, T.; Smith, T. S.; Binder-Markey, B.; Zaback, M.; Thompson, C. K.; Giszter, S.; Person, A.; Goulding, M.; Azim, E.; Thakor, N.; O`Connor, D.; Trimmer, B.; Q. Lima, S.; Car
10.1101/2023.02.21.529200 — neuroscience — Posted on 2023-02-22
982 Ketamine Effects on Energy Metabolism, Functional Connectivity and Working Memory in Healthy Humans
Driesen, N. R.; Herman, P.; Rowland, M. A.; Thompson, G.; Qiu, M.; He, G.; Fineberg, S. K.; Barron, D. S.; Helgeson, L.; Lacadie, C.; Chow, R.; Gueorguieva, R.; Straun, T.-C.; Krystal, J. H.; Hyder, F.
10.1101/2023.02.21.529425 — neuroscience — Posted on 2023-02-22
984 The use of DNA barcoding for the identification of giant hogweeds in the European North-East of Russia
Shadrin, D. M.; Dalke, I. V.; Zakhozhiy, I. G.; Shilnikov, D. S.; Kozhin, M. N.; Chadin, I. F.
10.1101/2023.02.21.529251 — plant biology — Posted on 2023-02-22
985 CLE11 and CLE10 Suppress Mycorrhizal Colonisation in Tomato
Wulf, K.; Wang, C.; Plagaro, T. H.; Kwon, C. T.; Velandia, K.; Lozano, A. C.; Navarrete, M. I. T.; Sun, J.; Reid, J. B.; Garcia-Garrido, J. M.; Foo, E.
10.1101/2023.02.21.529440 — plant biology — Posted on 2023-02-22
986 CETP inhibitor evacetrapib enters mouse brain tissue
Phenix, J.; Cote, J.; Dieme, D.; Recinto, S. J.; Oestereich, F.; Efrem, S.; Haddad, S.; Bouchard, M.; Munter, L. M.
10.1101/2023.02.21.529381 — pharmacology and toxicology — Posted on 2023-02-22
988 Increased endothelium activation and leakage do not promote diastolic dysfunction in mice fed with a high fat diet and treated with L-NAME
Cornuault, L.; Mora, P.; Rouault, P.; Foussard, N.; Chapouly, C.; Alzieu, P.; Gadeau, A.-P.; Couffinhal, T.; Renault, M.-A.
10.1101/2023.02.08.527684 — pathology — Posted on 2023-02-22
989 Flame (v2.0): advanced integration and interpretation of functional enrichment results from multiple sources
Karatzas, E.; Baltoumas, F.; Aplakidou, E.; Kontou, P.; Stathopoulos, P.; Stefanis, L.; Bagos, P.; Pavlopoulos, G. A.
10.1101/2023.02.21.529389 — bioinformatics — Posted on 2023-02-22
990 Reconstruction of TrkB complex assemblies and localizing an-tidepressant targets using Artificial Intelligence
Qian, C.; Xiang, X.; Yao, H.; Li, P.; Cheng, B.; Wei, D.; An, W.; Lu, Y.; Chu, M.; Wei, L.; Asakawa, T.; Xu, J.; Xia, F.; Liu, X.; Liu, B.-F.
10.1101/2023.02.21.529454 — bioinformatics — Posted on 2023-02-22
991 Phased nanopore assembly with Shasta and modular graph phasing with GFAse
Lorig-Roach, R.; Meredith, M.; Monlong, J.; Jain, M.; Olsen, H.; McNulty, B.; Porubsky, D.; Montague, T. G.; Lucas, J.; Condon, C.; Eizenga, J.; Juul, S.; McKenzie, S.; Simmonds, S.; Park, J.; Asri, M.; Koren, S.; Eichler, E.; Axel, R.; Martin, B.; Carnevali, P.; Miga, K.; Paten, B.
10.1101/2023.02.21.529152 — bioinformatics — Posted on 2023-02-22
993 Self-organization of Long-lasting Human Endothelial Capillary Networks guided by DLP Bioprinting
Mazari-Arrighi, E.; Ayollo, D.; Lepine, M.; Faivre, L.; Larghero, J.; Chatelain, F.; Fuchs, A.
10.1101/2023.02.21.529380 — bioengineering — Posted on 2023-02-22
997 Beak morphometry and morphogenesis across avian radiations
Mosleh, S.; Choi, G.; Musser, G. M.; James, H. F.; Abzhanov, A.; Mahadevan, L.
10.1101/2023.02.21.529429 — evolutionary biology — Posted on 2023-02-22
998 Transgenerational exposure to deoxygenation and warming disrupts mate-detection in Gammarus locusta
Pereira, B. P.; Neff, S.; Borges, F. O.; Otjacques, E.; Barreto, G.; Rannucci, M.; Court, M.; Rosa, R.; Repolho, T. F.; Paula, J. R.
10.1101/2023.02.21.529266 — ecology — Posted on 2023-02-22
999 Elevational Range Sizes of Woody plants Increase with Climate Variability in the Tropical Andes
Montano-Centellas, F. A.; Fuentes, A. F.; Cayola, L.; Macia, M. J.; Arellano, G.; Loza, M. I.; Nieto-Ariza, B.; Tello, J. S.
10.1101/2023.02.21.529430 — ecology — Posted on 2023-02-22
1003 Signalling-dependent refinement of cell fate choice during tissue remodelling
Herszterg, S.; de Gennes, M.; Cicolini, S.; Huang, A.; Alexandre, C.; Smith, M. B.; Araujo, H.; Vincent, J.-P.; Salbreux, G.
10.1101/2023.02.21.529250 — developmental biology — Posted on 2023-02-22
1004 OSBP-mediated PI(4)P-cholesterol exchange at endoplasmic reticulum-secretory granule contact sites controls insulin secretion
Panagiotou, S.; Nguyen, P. M.; Tan, K.-W.; Mueller, A.; Wendt, A.; Eliasson, L.; Tengholm, A.; Solimena, M.; Idevall-Hagren, O.
10.1101/2023.02.22.529485 — cell biology — Posted on 2023-02-22
1005 Rab12 regulates LRRK2 activity by promoting its localization to lysosomes
Bondar, V. V.; Wang, X.; Davis, O. B.; Maloney, M. T.; Agam, M.; Chin, M. Y.; Ho, A. C.-N.; Joy, D.; Lewcock, J. W.; Di Paolo, G.; Thorne, R. G.; Sweeney, Z. K.; Henry, A. G.
10.1101/2023.02.21.529466 — cell biology — Posted on 2023-02-22
1007 Differential labelling of human sub-cellular compartments with fluorescent dye esters and expansion microscopy
Sheard, T. M. D.; Shakespeare, T.; Seehra, R. S.; Spencer, M. E.; Suen, K. M.; Jayasinghe, I.
10.1101/2023.02.21.529394 — cell biology — Posted on 2023-02-22
1008 Mechanisms of Nuclear Pore Complex disassembly by the mitotic Polo-Like Kinase 1 (PLK-1) in C. elegans embryos
Nkombo Nkoula, S.; Velez-Aguilera, G.; Ossareh-Nazari, B.; Van Hove, L.; Ayuso, C.; Legros, V.; Chevreux, G.; Thomas, L.; Seydoux, G.; Askjaer, P.; PINTARD, L.
10.1101/2023.02.21.528438 — cell biology — Posted on 2023-02-22
1009 Benchmarking the accuracy of structure-based binding affinity predictors on Spike-ACE2 Deep Mutational Interaction Set
Ozden, B.; Samiloglu, E.; Erguven, M.; Yukruk, C.; Kosaca, M.; Oktayoglu, M.; Mentes, M.; Arslan, N.; Karakulah, G.; Barlas, A. B.; Savas, B.; Karaca, E.
10.1101/2022.04.18.488633 — bioinformatics — Posted on 2023-02-22
1010 Single-cell transcriptional analysis of lamina propria lymphocytes in the jejunum reveals ILC-like cells in pigs
Wang, J.; Cheng, M.; Gao, M.; Sun, Y.; Lu, Y.; Li, X.; Shi, C.; Wang, J.; Wang, N.; Yang, W.; Jiang, Y.; Huang, H.; Yang, G.; Zeng, Y.; Wang, C.; Cao, X.
10.1101/2023.01.01.522424 — immunology — Posted on 2023-02-22
1020 Socio-cultural practices affect sexual dimorphism in stature in Early Neolithic Europe
Cox, S. L.; Nicklisch, N.; Francken, M.; Wahl, J.; Meller, H.; Haak, W.; Alt, K. W.; Rosenstock, E.; Mathieson, I.
10.1101/2023.02.21.529406 — genetics — Posted on 2023-02-21
1026 DAXX safeguards heterochromatin formation in embryonic stem cells
Canat, A.; Veillet, A.; Batrin, R.; Dubourg, C.; Illingworth, R. S.; Fabre, E.; Therizols, P.
10.1101/2021.04.28.441827 — molecular biology — Posted on 2023-02-21
1028 Characterization of a novel polyextremotolerant fungus, Exophiala viscosa, with insights into its melanin regulation and ecological niche
Carr, E. C.; Barton, Q.; Grambo, S.; Renfro, C.; Sullivan, M. T.; Kuo, A.; Pangilinan, J.; Lipzen, A.; Keymanesh, K.; Savage, E.; Barry, K.; Grigoriev, I. V.; Riekhof, W. R.; Harris, S. D.
10.1101/2021.12.03.471027 — microbiology — Posted on 2023-02-21
1029 Palmitoylation of gasdermin D directs its membrane translocation and pore formation in pyroptosis
Balasubramanian, A.; Ghimire, L.; Hsu, A. Y.; Kambara, H.; liu, X.; Hasegawa, T.; xu, R.; Tahir, M.; Yu, H.; Lieberman, J.; Luo, H. R.
10.1101/2023.02.21.529402 — immunology — Posted on 2023-02-21
1030 Systematic characterization of brain cellular crosstalk reveals a novel role for SEMA6D in TREM2-associated microglial function in Alzheimer's disease
D'Oliveira Albanus, R.; Finan, G. M.; Brase, L.; Chen, S.; Guo, Q.; Kannan, A.; Acquarone, M.; You, S.-F.; Novotny, B. C.; Ribeiro Pereira, P. M.; Morris, J. C.; Holtzman, D. M.; McDade, E.; Farlow, M.; Chhatwal, J. P.; Dominantly Inherited Alzheimer Network (DIAN), ; Mace, E. E.; Benitez, B. A.; Piccio, L.; Sutherland, G. T.; Ma, Q.; Fu, H.; Karch, C. M.; Harari, O.; Kim, T.-W.
10.1101/2022.11.11.516215 — neuroscience — Posted on 2023-02-21
1031 Tau in cerebrospinal fluid induces neuronal hyperexcitability and alters hippocampal theta oscillations
Brown, J.; Camporesi, E.; Lantero-Rodriguez, J.; Olsson, M.; Wang, A.; Medem, B.; Zetterberg, H.; Blennow, K.; Wall, M. J.; Karikari, T. K.; Hill, E.
10.1101/2023.01.24.525362 — neuroscience — Posted on 2023-02-21
1033 Deep trans-omic network fusion reveals altered synaptic network in Alzheimer's Disease
Xie, L.; Raj, Y.; Varathan, P.; He, B.; Nho, K.; Risacher, S. L.; Salama, P.; Saykin, A. J.; Yan, J.
10.1101/2022.05.02.490336 — systems biology — Posted on 2023-02-21
1034 CD99 Promotes Self-renewal in Hematopoietic Stem Cells and Leukemia Stem Cells by Regulating Protein Synthesis
Huang, Y.; Kapti, E. G.; Ji, Y.; Thomas, T.; Dempsey, J.; Mims, K.; Berezniuk, I.; Guo, L.; Kroger, B.; Hu, W.; Park, C. Y.; Chung, S. S.
10.1101/2023.02.21.529419 — cancer biology — Posted on 2023-02-21
1035 Metastatic potential in clonal melanoma cells is driven by a rare, early-invading subpopulation
Kaur, A.; Cuenca, L.; Kiani, K.; Busch, G.; Fingerman, D.; Dunagin, M. C.; Li, J.; Dardani, I.; Sanford, E. M.; Pemberton, J.; Goyal, Y.; Weeraratna, A. T.; Herlyn, M.; Raj, A.
10.1101/2022.04.17.488591 — cancer biology — Posted on 2023-02-21
1036 Multi-modal digital pathology for colorectal cancer diagnosis by high-plex immunofluorescence imaging and traditional histology of the same tissue section
Lin, J.-R.; Chen, Y.-A.; Campton, D.; Cooper, J.; Coy, S.; Yapp, C.; Tefft, J.; McCarty, E.; Ligon, K.; Rodig, S. J.; Reese, S.; George, T.; Santagata, S.; Sorger, P. K.
10.1101/2022.09.28.509927 — cancer biology — Posted on 2023-02-21
1038 Novel Methods for Multi-ancestry Polygenic Prediction and their Evaluations in 5.1 Million Individuals of Diverse Ancestry
Zhang, H.; Zhan, J.; Jin, J.; Lu, W.; Zhao, R.; Ahearn, T. U.; Yu, Z.; O'Connell, J.; Jiang, Y.; Chen, T.; Okuhara, D.; 23andMe Research Team, ; Garcia-Closas, M.; Lin, X.; Koelsch, B. L.; Chatterjee, N.
10.1101/2022.03.24.485519 — genetics — Posted on 2023-02-21
1039 Phylogenomic Testing of Root Hypotheses
Tria, F. D. K.; Landan, G.; Picazo, D. R.; Dagan, T.
10.1101/758581 — evolutionary biology — Posted on 2023-02-21
1042 Intra-annual temperature variability and nutrient enrichment drive seasonal beta-diversity in global grasslands
Garbowski, M.; Boughton, E.; Ebling, A.; Fay, P.; Hautier, Y.; Holz, H.; Jentsch, A.; Jurburg, S. D.; Ladouceur, E.; Martina, J.; Ohlert, T.; Raynaud, X.; Roscher, C.; Sonnier, G.; Tognetti, P. M.; Yahdjian, L.; Wilfahrt, P.; Harpole, W. S.
10.1101/2022.10.24.513509 — ecology — Posted on 2023-02-21
1045 Anticodon sequence determines the impact of mistranslating tRNAAla variants
Cozma, E.; Rao, M.; Dusick, M.; Genereaux, J.; Rodriguez-Mias, R. A.; Villen, J.; Brandl, C. J.; Berg, M. D.
10.1101/2022.11.23.517754 — molecular biology — Posted on 2023-02-21
1046 Regional Gene Expression in the Retina, Optic Nerve Head, and Optic Nerve of Mice with Experimental Glaucoma and Optic Nerve Crush
Keuthan, C. J.; Schaub, J.; Wei, M.; Fang, W.; Quillen, S.; Kimball, E.; Johnson, T. V.; Ji, H.; Zack, D. J.; Quigley, H. A.
10.1101/2023.02.21.529410 — molecular biology — Posted on 2023-02-21
1050 The Hsf1-sHsp cascade has pan-antiviral activity in mosquitoes
Qu, J.; Schinkel, M.; Chiggiato, L.; Rosendo Machado, S.; Overheul, G. J.; Miesen, P.; van Rij, R. P.
10.1101/2023.02.21.529413 — immunology — Posted on 2023-02-21
1051 Exploratory mass cytometry analysis reveals immunophenotypes of cancer treatment-related pneumonitis
Yanagihara, T.; Hata, K.; Matsubara, K.; Kunimura, K.; Suzuki, K.; Tsubouchi, K.; Ikegame, S.; Baba, Y.; Fukui, Y.; Okamoto, I.
10.1101/2023.02.21.529383 — immunology — Posted on 2023-02-21
1052 Metabolic sensor AMPK licenses CD103+ dendritic cells to induce Treg responses
Patente, T.; Brombacher, E.; Heieis, G.; Pelgrom, L.; Zawistowska-Deniziak, A.; Otto, F.; Ozir-Fazalalikhan, A.; van der Ham, A.; Guigas, B.; Barbuto, J. A. M.; Everts, B.
10.1101/2023.02.21.528293 — immunology — Posted on 2023-02-21
1053 Correspondence between the layered structure of deep language models and temporal structure of natural language processing in the human brain
Goldstein, A.; Ham, E.; Nastase, S. A.; Zada, Z.; Dabush, A.; Bobbi Aubrey, B.; Schain, M.; Gazula, H.; Feder, A.; Doyle, W.; Devore, S.; Dugan, P.; Friedman, D.; Brenner, M.; Hassidim, A.; Devinsky, O.; Flinker, A.; Levy, O.; Hasson, U.
10.1101/2022.07.11.499562 — neuroscience — Posted on 2023-02-21
1055 Is resting state fMRI better than individual characteristics at predicting cognition?
Omidvarnia, A.; Sasse, L.; Larabi, D. I.; Raimondo, F.; Hoffstaedter, F.; Kasper, J.; Dukart, J.; Petersen, M.; Cheng, B.; Thomalla, G.; Eickhoff, S. B.; Patil, K. R.
10.1101/2023.02.18.529076 — neuroscience — Posted on 2023-02-21
1057 Optimizing linear ion trap data independent acquisition towards single cell proteomics
Phlairaharn, T.; Ye, Z.; Krismer, E.; Pedersen, A.-K.; Pietzner, M.; Olsen, J. V.; Schoof, E. M.; Searle, B. C.
10.1101/2023.02.21.529444 — biochemistry — Posted on 2023-02-21
1058 A methyl-seq tool to capture genomic imprinted loci
Hubert, J.-N.; Iannuccelli, N.; Cabau, C.; Jacomet, E.; Billon, Y.; Serre, R.-F.; Vandecasteele, C.; Donnadieu, C.; Demars, J.
10.1101/2023.02.21.529206 — genomics — Posted on 2023-02-21
1059 TET1 Catalytic Activity is Required for Reprogramming of Imprinting Control Regions and Patterning of Sperm-Specific Hypomethylated Regions
Prasasya, R. D.; Caldwell, B. A.; Liu, Z.; Wu, S.; Leu, N. A. D.; Fowler, J. M.; Cincotta, S. A.; Laird, D. J.; Kohli, R. M.; Bartolomei, M.
10.1101/2023.02.21.529426 — developmental biology — Posted on 2023-02-21
1062 FitMultiCell: Simulating and parameterizing computational models of multi-scale and multi-cellular processes
Alamoudi, E.; Schalte, Y.; Muller, R.; Starruss, J.; Bundgaard, N.; Graw, F.; Brusch, L.; Hasenauer, J.
10.1101/2023.02.21.528946 — systems biology — Posted on 2023-02-21
1063 ABCH2 transporter in the first line of defense protects malaria vectors from pyrethroids
Kefi, M.; Balabanidou, V.; Sarafoglou, C.; Charamis, J.; Lycett, G.; Ranson, H.; Gouridis, G.; Vontas, J.
10.1101/2023.02.21.529359 — evolutionary biology — Posted on 2023-02-21
1065 Comparing the transmission of carbapenemase-producing and extended-spectrum beta-lactamase-producing Escherichia coli between broiler chickens.
Dankittipong, N.; Alderliesten, J. B.; Van den Broek, J.; Dame-Korevaar, A. M.; Brouwer, M. S.; Velkers, F. C.; Bossers, A.; de Vos, C. J.; Wagenaar, J. A.; Stegeman, A. J.; Fischer, E. A. J.
10.1101/2023.02.21.529369 — microbiology — Posted on 2023-02-21
1066 Short- and long-term effects of continuous compost amendment on soil microbiome community
Cohen, J.; Zolti, A.; Rotbart, N.; Bar-Tal, A.; Laor, Y.; Medina, S.; Shawahna, R.; Saadi, I.; Raviv, M.; Green, S. J.; Yermiyahu, U.; Minz, D.
10.1101/2023.02.21.529350 — microbiology — Posted on 2023-02-21
1067 Distinct neurochemical influences on fMRI response polarity in the striatum
Cerri, D. H.; Albaugh, D. L.; Walton, L. R.; Katz, B.; Wang, T.-W.; Chao, T.-H. H.; Zhang, W.; Nonneman, R. J.; Jiang, J.; Lee, S.-H.; Etkin, A.; Hall, C. N.; Stuber, G. D.; Shih, Y.-Y. I.
10.1101/2023.02.20.529283 — neuroscience — Posted on 2023-02-21
1069 A cranial implant for stabilizing whole-cell patch-clamp recordings in behaving rodents
Dacre, J.; Sanchez-Rivera, M.; Schiemann, J.; Currie, S.; Ammer, J.; Duguid, I.
10.1101/2023.02.21.529357 — neuroscience — Posted on 2023-02-21
1071 Neuromechanical strategies for obstacle negotiation during overground locomotion following an incomplete spinal cord injury in adult cats
Lecomte, C. G.; Mari, S.; Audet, J.; Yassine, S.; Merlet, A. N.; Morency, C.; Harnie, J.; Beaulieu, C.; Gendron, L.; Frigon, A.
10.1101/2023.02.21.529373 — neuroscience — Posted on 2023-02-21
1072 Active site mutations of F420-dependent alkene reductases reverse stereoselectivity
Kang, S. W.; Antoney, J. P.; Lupton, D. W.; Speight, R.; Scott, C.; Jackson, C. J.
10.1101/2023.02.21.529347 — synthetic biology — Posted on 2023-02-21
1074 Androgen Receptor driven gene score identifies tumors with Epithelial to Mesenchymal Transition features in triple negative breast cancer
Rajarajan, S.; VP, S.; CE, A.; Nair, M.; Mavetkar, A. D.; Naidu, C. M.; Patil, S.; Nimbalkar, V. P.; Pillai, M.; Jolly, M. K.; Sabarinathan, R.; Ramesh, R. S.; BS, S.; Prabhu, J. S.
10.1101/2023.02.21.529333 — cancer biology — Posted on 2023-02-21
1075 OPTIMAL: An OPTimsed Imaging Mass cytometry AnaLysis framework for Segmentation and Data Exploration
Hunter, B.; Nicorescu, I.; Foster, E.; McDonald, D.; Hulme, G.; Thomson, A.; Hilkens, C.; Majo, J.; Milross, L.; Fisher, A. J.; Wills, J. W.; Rees, P.; Filby, A.; Merces, G.
10.1101/2023.02.21.526083 — bioinformatics — Posted on 2023-02-21
1076 Comparison between Canine and Porcine Models of Chronic Deep Venous Thrombosis
Wang, C.; Tang, T.; Ye, S.-L.; Jiang, X.-D.; Xiang, G.-Y.; Xiao, L.; Wang, L.-L.; Xu, T.; Song, B.; Hu, N.; Du, X.-L.; Li, X.-Q.
10.1101/2023.02.20.529322 — animal behavior and cognition — Posted on 2023-02-21
1078 Evolutionary changes in germ granule mRNA content are driven by multiple mechanisms in Drosophila
Doyle, D. A.; Burian, F. N.; Aharoni, B.; Klinder, A. J.; Menzel, M. M.; Nifras, G. C. C.; Shabazz-Henry, A. L.; Ulrich Palma, B.; Hidalgo, G. A.; Sottolano, C. J.; Ortega, B. M.; Niepielko, M. G.
10.1101/2023.02.21.529147 — evolutionary biology — Posted on 2023-02-21
1079 Drug metabolic activity as a selection factor for pluripotent stem cell-derived hepatic progenitor cells
Akiyama, S.; Saku, N.; Miyata, S.; Ite, K.; Nonaka, H.; Toyoda, M.; Kamiya, A.; Kiyono, T.; Kimura, T.; Kasahara, M.; Umezawa, A.
10.1101/2023.02.21.529337 — cell biology — Posted on 2023-02-21
1081 Interferon inhibits a model RNA virus via a limited set of inducible effector genes
McDougal, M. B.; De Maria, A. M.; Ohlson, M. B.; Kumar, A.; Xing, C.; Schoggins, J. W.
10.1101/2023.02.21.529297 — microbiology — Posted on 2023-02-21
1082 Immunostimulatory effects of Bacillus coagulans SANK70258
Ikeda, Y.; Ito, N.; Yamashita, N.; Minamikawa, N.; Nagata, K.; Yashiro, T.; Aida, M.; Yamada, R.; Hachisu, M.; Nishiyama, C.
10.1101/2023.02.21.529342 — immunology — Posted on 2023-02-21
1084 Selective IL-27 production by intestinal regulatory T cells permits gut-specific regulation of Th17 immunity
Lin, C.-H.; Wu, C.-J.; Cho, S.; Patkar, R.; Lin, L.-L.; Chen, M.-C.; Israelsson, E.; Betts, J.; Niedzielska, M.; Patel, S. A.; Duong, H. G.; Gerner, R. R.; Hsu, C.-Y.; Catley, M.; Maciewicz, R. A.; Chu, H.; Raffatellu, M.; Chang, J. T.; Lu, L.-F.
10.1101/2023.02.20.529261 — immunology — Posted on 2023-02-21
1087 Gut microbiota promotes pain chronicity in Myosin1A deficient male mice
Reynders, A.; Jhumka, A.; Gaillard, S.; Hoeffel, G.; Mantilleri, A.; Malapert, P.; Salio, C.; Ugolini, S.; Castets, F.; Saurin, A. J.; Serino, M.; Moqrich, A.
10.1101/2023.02.21.529352 — neuroscience — Posted on 2023-02-21
1088 Low-threshold, high-resolution, chronically stable intracortical microstimulation by ultraflexible electrodes
Lycke, R.; Kim, R.; Zolotavin, P.; Montes, J.; Koszeghy, A.; Altun, E.; Noble, B.; Yin, R.; He, F.; Totah, N.; Xie, C.; Luan, L.
10.1101/2023.02.20.529295 — neuroscience — Posted on 2023-02-21
1089 Plasticity of gene expression in the nervous system by exposure to environmental odorants that inhibit HDACs
Haga-Yamanaka, S.; Nunez-Flores, R.; Scott, C. A.; Perry, S.; Chen, S. T.; Pontrello, C.; Nair, M. G.; Ray, A.
10.1101/2023.02.21.529339 — neuroscience — Posted on 2023-02-21
1090 Brain network analysis in Parkinson's disease patients based on graph theory
Akbari, S.; Deevband, M. R.; Alvar, A. A.; Zadeh, E. F.; Tabar, H. R.; Kelley, P.; Tavakoli, M.
10.1101/2023.02.21.529361 — neuroscience — Posted on 2023-02-21
1091 A Metabolomics Study of Thrombosis after Cardiac Surgery in Children with Congenital Heart Disease
Li, S.; Watson, D.; Jorgenson, A.; Adelekan, Z.; Tang, W.; Garland, K.; Zupancich, L.; Edens, R. E.; Overman, D. M. M.; Huntley, M. T.
10.1101/2023.02.20.529324 — physiology — Posted on 2023-02-21
1093 Proteome allocation is linked to transcriptional regulation through a modularized transcriptome
Patel, A.; McGrosso, D.; Hefner, Y.; Campeau, A.; Sastry, A. V.; Maurya, S.; Rychel, K.; Gonzalez, D. J.; Palsson, B. O.
10.1101/2023.02.20.529291 — bioengineering — Posted on 2023-02-21
1095 High-throughput screening of functional neo-antigens and their specific TCRs via the Jurkat reporter system combine with droplet microfluidics
Li, Y.; Qi, J.; Liu, Y.; Zheng, Y.; Zhu, H.; Zang, Y.; Guan, X.; Xie, S.; Zhao, H.; Fu, Y.; Xiang, H.; Zhang, W.; Chen, H.; Liu, H.; Zhao, Y.; Feng, Y.; Bu, F.; Liang, Y.; Li, Y.; Xu, Q.; He, Y.; Sun, L.; Liu, L.; Gu, Y.; Xu, X.; HOU, Y.; Dong, X.; Liu, Y.
10.1101/2023.02.20.529171 — bioengineering — Posted on 2023-02-21
1096 Hypoxia-inducible factor 2 is a key determinant of manganese excess and polycythemia in SLC30A10 deficiency
Prajapati, M.; Zhang, J. Z.; Mercadante, C. J.; Kowalski, H. L.; Delaney, B.; Anderson, J. A.; Guo, S.; Aghajan, M.; Bartnikas, T. B.
10.1101/2023.02.20.529270 — genetics — Posted on 2023-02-21
1097 Bacteriophage therapy for the treatment of Mycobacterium tuberculosis infections in humanized mice
Yi, G.; Yang, F.; Labani-Motlagh, A.; Moreira, J. D.; Ansari, D.; Bohorquez, J. A.; Patel, S.; Spagnolo, F.; Florence, J.; Vankayalapati, A.; Vankayalapati, R.; Dennehy, J. J. D. J.; Samten, B.
10.1101/2023.01.23.525188 — microbiology — Posted on 2023-02-21
1098 The oncogenic role of Streptococcus gallolyticus subsp. gallolyticus is linked to activation of multiple cancer-related signaling pathways
Pasquereau-Kotula, E.; Nigro, G.; Dingli, F.; Loew, D.; Poullet, P.; Xu, Y.; Kopetz, S.; Davis, J.; Peduto, L.; Robbe-Masselot, C.; Sansonetti, P.; Trieu-Cuot, P.; Dramsi, S.
10.1101/2023.02.17.528913 — microbiology — Posted on 2023-02-21
1100 Selective targeting of α4β7/MAdCAM-1 axis suppresses fibrosis progression in chronic liver disease
Gupta, B.; Rai, R. P.; Pal, P. B.; Chaudhary, S.; Chiaro, A.; Seaman, S.; Singhi, A. D.; Monga, S. P.; Iyer, S. S.; Raeman, R.
10.1101/2023.02.20.528201 — immunology — Posted on 2023-02-21
1101 Targeting the MR1-MAIT Cell Axis Improves Vaccine Efficacy and Affords Protection against Viral Pathogens
Rashu, R.; Ninkov, M.; Wardell, C. M.; Benoit, J. M.; Wang, N. I.; D'Agostino, M. R.; Zhang, A.; Feng, E.; Saeedian, N.; Bell, G. I.; Vahedi, F.; Hess, D. A.; Troyer, R. M.; Kang, C. Y.; Ashkar, A. A.; Miller, M. S.; Haeryfar, S. M. M.
10.1101/2023.02.20.529311 — immunology — Posted on 2023-02-21
1104 Substrate evaporation drives collective construction in termites
Facchini, G.; Rathery, A.; Douady, S.; Sillam-Dusses, D.; Perna, A.
10.1101/2023.02.17.528984 — biophysics — Posted on 2023-02-21
1107 Optical tools for visualizing and controlling human GLP-1 receptor activation with high spatiotemporal resolution
Duffet, L.; Williams, E. T.; Gresch, A.; Chen, S.; Bhat, M. A.; Benke, D.; Hartrampf, N.; Patriarchi, T.
10.1101/2023.02.14.528498 — biochemistry — Posted on 2023-02-21
1109 Pan-genotypic probe-based enrichment to improve efficiency of Hepatitis B virus sequencing
Lumley, S. F.; Jennings, D.; Waddilove, E.; Trebes, A.; Delphin, M.; Downs, L. O.; Macintyre-Crockett, G.; Wu, Y.; Chaudron, S.; de Lara, C.; Chai, H.; Maponga, T.; Martin, J.; Collier, J.; Ip, C.; Barnes, E.; Bonsall, D.; Piazza, P.; Ansari, M. A.; Matthews, P. C.
10.1101/2023.02.20.529276 — genomics — Posted on 2023-02-21
1110 The long-term effects of genomic selection: 2. Changes in allele frequencies of causal loci and new mutations
Wientjes, Y. C. J.; Bijma, P.; van den Heuvel, J.; Zwaan, B. J.; Vitezica, Z. G.; Calus, M. P. L.
10.1101/2023.02.20.529287 — genetics — Posted on 2023-02-21
1112 Accounting for population growth, intermittent breeding, and aging error in close-kin mark-recapture assessments
Swenson, J. D.; Brooks, E. N.; Kacev, D.; Boyd, C.; Kinney, M.; Marcy-Quay, B.; Seveque, A.; Feldheim, K.; Komoroske, L. M.
10.1101/2023.02.20.529265 — ecology — Posted on 2023-02-21
1114 A novel HERC4-dependent glue degrader targeting STING
Mutlu, M.; Schmidt, I.; Morrison, A. I.; Goretzki, B.; Freuler, F.; Begue, D.; Pythoud, N.; Ahrne, E.; Kapps, S.; Roest, S.; Bonenfant, D.; Jeanpierre, D.; Tran, T.-T.-T.; Maher, R.; An, S.; Rietsch, A.; Nigsch, F.; Hofmann, A.; Reece-Hoyes, J.; Parker, C. N.; Guerini, D.
10.1101/2023.02.08.527642 — molecular biology — Posted on 2023-02-21
1115 Pilotins are mobile T3SS components involved in assembly and substrate specificity of the bacterial type III secretion system
Wimmi, S.; Fleck, M.; Helbig, C.; Brianceau, C.; Langenfeld, K.; Szymanski, W.; Angelidou, G.; Glatter, T.; Diepold, A.
10.1101/2022.02.14.480308 — microbiology — Posted on 2023-02-21
1116 Community composition and the environment modulate the population dynamics of type VI secretion in human gut bacteria
Robitaille, S.; Simmons, E. L.; Verster, A. J.; McClure, E. A.; Royce, D.; Trus, E. M.; Swartz, K.; Schultz, D.; Nadell, C. D.; Ross, B. D.
10.1101/2023.02.20.529031 — microbiology — Posted on 2023-02-21
1118 MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression
Chen, J.; Zheng, Q.; Hicks, J. L.; Trabzonlu, L.; Ozbek, B.; Jones, T.; Vaghasia, A.; Larman, T. C.; Wang, R.; Markowski, M. C.; Denmeade, S. R.; Pienta, K. J.; Hruban, R. H.; Antonaraskis, E. S.; Gupta, A.; Dang, C. V.; Yegnasubramanian, S.; De Marzo, A. M.
10.1101/2023.02.20.529259 — cancer biology — Posted on 2023-02-21
1119 Europe PMC Annotated Full-text Corpus for Gene/Proteins, Diseases and Organisms
Yang, X.; Saha, S.; Venkatesan, A.; Tirunagari, S.; Vartak, V.; McEntyre, J.
10.1101/2023.02.20.529292 — bioinformatics — Posted on 2023-02-21
1120 Microwell-enhanced optical detection of single bacteria
Roslon, I.; Japaridze, A.; Rodenhuis, S.; Hamoen, L.; Ghatkesar, M.; Steeneken, P.; Dekker, C.; Alijani, F.
10.1101/2023.02.20.529233 — bioengineering — Posted on 2023-02-21
1121 Development and evaluation of a wearable peripheral vascular compensation sensor in a swine model of hemorrhage
Bonetta-Misteli, F.; Collins, T.; Pavek, T.; Carlgren, M.; Frolova, A.; Shmuylovich, L.; O'Brien, C. M.
10.1101/2023.02.20.529156 — bioengineering — Posted on 2023-02-21
1123 Recognition and Cleavage of Human tRNA Methyltransferase TRMT1 by the SARS-CoV-2 Main Protease
D'Oliviera, A.; Dai, X.; Mottaghinia, S.; Geissler, E. P.; Etienne, L.; Zhang, Y.; Mugridge, J. S.
10.1101/2023.02.20.529306 — biochemistry — Posted on 2023-02-21
1124 Characterization of the First Turtle Organoids: A Model for Investigating Unique Adaptations with Biomedical Potential
Zdyrski, C.; Gabriel, V.; Gessler, T. B.; Ralston, A.; Sifuentes-Romero, I.; Kundu, D.; Honold, S.; Wickham, H.; Topping, N. E.; Sahoo, D. K.; Bista, B.; Tamplin, J.; Ospina, O.; Pineyro, P.; Meyerholz, D. K.; Allenspach, K.; Mochel, J. P.; Valenzuela, N.
10.1101/2023.02.20.527070 — genetics — Posted on 2023-02-21
1125 Efficient Viral Capture and Inactivation from Bioaerosols Using Electrostatic Precipitation.
Preston, H. E.; Bayliss, R.; Temperton, N. J.; Mayora Neto, M.; Brewer, J.; Parker, A. L.
10.1101/2023.02.19.529105 — microbiology — Posted on 2023-02-21
1127 Adult thymus-derived cMaf+ RORγt+ γδ T cells lack Scart2 chromatin accessibility and do not reach periphery
Yang, T.; Barros-Martins, J.; Janssen, A.; Wang, Z.; Leon-Lara, X.; Weiss, S.; Prinz, I.; Foerster, R.; Ravens, S.
10.1101/2023.02.20.529224 — immunology — Posted on 2023-02-21
1128 Mechanisms of neutralizing antibody response probed using synthetic virus-like structures
Wholey, W.-Y.; Meyer, A. R.; Yoda, S.-T.; Chackerian, B.; Zikherman, J.; Cheng, W.
10.1101/2023.02.20.529089 — immunology — Posted on 2023-02-21
1129 Single shot dendritic cell targeting SARS-CoV-2 vaccine candidate induces broad and durable systemic and mucosal immune responses
Cheang, N. Y. Z.; Tan, P. S.; Purushotorman, K.; Yap, W. C.; Chua, B. Y. L.; Tan, K. S.; Tullett, K. M.; Yeoh, A. Y.-Y.; Tan, C. Q. H.; Qian, X.; Tay, D. J. W.; Caminschi, I.; Tan, Y. J.; MacAry, P. A.; Tan, C. W.; Lahoud, M. H.; Alonso, S.
10.1101/2023.02.21.529344 — immunology — Posted on 2023-02-21
1131 Retinoic acid and proteotoxic stress induce AML cell death overcoming stromal cell protection
Liccardo, F.; Sniegocka, M.; Tito, C.; Iaiza, A.; Ottone, T.; Divona, M.; Travaglini, S.; Mattei, M.; Cicconi, R.; Miglietta, S.; Familiari, G.; Nottola, S. A.; Petrozza, V.; Tamagnone, L.; Voso, M. T.; Masciarelli, S.; Fazi, F.
10.1101/2023.02.20.529204 — cancer biology — Posted on 2023-02-21
1133 PANGEA: A New Gene Set Enrichment Tool for Drosophila and Common Research Organisms
Hu, Y.; Comjean, A.; Attrill, H.; Antonazzo, G.; Thurmond, J.; Li, F.; Chao, T.; Mohr, S.; Brown, N. H.; Perrimon, N.
10.1101/2023.02.20.529262 — bioinformatics — Posted on 2023-02-21
1138 A Mechanistic Insight into Sources of Error of Visual Working Memory in Multiple Sclerosis
Motahharynia, A.; Pourmohammadi, A.; Adibi, A.; Shaygannejad, V.; Ashtari, F.; Adibi, I.; Sanayei, M.
10.1101/2023.02.20.529229 — neuroscience — Posted on 2023-02-21
1139 High Efficiency Rare Earth Element Biomining with Systems Biology Guided Engineering of Gluconobacter oxydans
Schmitz, A. M.; Pian, B.; Marecos, S.; Wu, M.; Holycross, M. E.; Gazel, E.; Reid, M. C.; Barstow, B.
10.1101/2023.02.09.527855 — synthetic biology — Posted on 2023-02-21
1140 Centrosome Amplification promotes cell invasion via cell-cell contact disruption and Rap-1 activation
Prakash, A.; Paunikar, S.; Webber, M.; McDermott, E.; Vellanki, S. H.; Thompson, K.; Dockery, P.; Jahns, H.; Brown, J. A. L.; Hopkins, A. M.; Bourke, E.
10.1101/2022.05.09.490051 — cell biology — Posted on 2023-02-21
1141 Clarifying the biological and statistical assumptions of cross-sectional biological age predictors
Sluiskes, M. H.; Goeman, J. J.; Beekman, M.; Slagboom, P. E.; Putter, H.; Rodriguez-Girondo, M.
10.1101/2023.01.01.522413 — molecular biology — Posted on 2023-02-21
1144 Human Arm Redundancy - A New Approach for the Inverse Kinematics Problem
Barliya, A.; Krausz, N.; Naaman, H.; Chiovetto, E.; Giese, M. A.; Flash, T.
10.1101/2023.02.20.528995 — neuroscience — Posted on 2023-02-21
1147 Tenacibaculosis in wild-caught, captive Chinook salmon (Oncorhynchus tshawytscha) in British Columbia, Canada
Di Cicco, E.; Zinn, K. R.; Johnston, S. D.; Kaukinen, K. H.; Li, S.; Archambault, J. F.; Mantha-Rensi, K. N. R.; Zielke, K. A. J.; Bugg, W. S.; Mordecai, G. J.; Bass, A. L.; Deeg, C. M.; Bateman, A. W.; Hinch, S. G.; Miller, K. M.
10.1101/2023.02.17.529034 — pathology — Posted on 2023-02-21
1148 Quantitative model of aging-related muscle degeneration: a Drosophila study
Chechenova, M.; Stratton, H.; Kiani, K.; Gerberich, E.; Alekseyenko, A.; Tamba, N.; An, S.; Czajkowski, E.; Castillo, L.; Talley, C.; Bryantsev, A.
10.1101/2023.02.19.529145 — pathology — Posted on 2023-02-21
1149 Patient-derived organoids identify tailored therapeutic options and determinants of plasticity in sarcomatoid urothelial bladder cancer
Garioni, M.; Blukacz, L.; Nuciforo, S.; Parmentier, R.; Roma, L.; Coto-llerena, M.; Pueschel, H.; Piscuoglio, S.; Vlajnic, T.; Stenner, F.; Seifert, H.-H.; Rentsch, C. A.; Bubendorf, L.; Le Magnen, C.
10.1101/2023.02.20.528313 — cancer biology — Posted on 2023-02-21
1150 Field cancerization impacts tumor development, T-cell exhaustion and clinical outcomes in bladder cancer
Strandgaard, T.; Nordentoft, I.; Birkenkamp-Demtroder, K.; Salminen, L.; Prip, F.; Rasmussen, J.; Andreasen, T. G.; Lindskrog, S. V.; Christensen, E.; Lamy, P.; Knudsen, M.; Steiniche, T.; Jensen, J. B.; Dyrskjot, L.
10.1101/2023.02.20.528920 — cancer biology — Posted on 2023-02-21
1151 Multi-omics and Pharmacological Characterization of Patient-derived Glioma Cell Lines
Wu, M.; Yuan, R.; Ji, N.; Lu, T.; Wang, T.; Zhang, J.; Li, M.; Cao, P.; Zhao, J.; Li, G.; Li, J.; Li, Y.; Tang, Y.; Gao, Z.; Wang, X.; Wu, A.; Cheng, W.; Ge, M.; Cui, G.; You, Y.; Zhang, W.; Wang, Q.; Chen, J.
10.1101/2023.02.20.529198 — cancer biology — Posted on 2023-02-21
1152 Direct optical nanoscopy unveils signatures of cytokine-induced β-cell structural and functional stress
Pugliese, L. A.; De Lorenzi, V.; Bernardi, M.; Ghignoli, S.; Tesi, M.; Marchetti, P.; Cardarelli, F.; Pesce, L.
10.1101/2023.02.20.529190 — biophysics — Posted on 2023-02-21
1153 Likelihood-based docking of models into cryo-EM maps
Millan, C.; McCoy, A. J.; Terwilliger, T. C.; Read, R. J.
10.1101/2022.12.20.521188 — biophysics — Posted on 2023-02-21
1157 Tracing cancer evolution and heterogeneity using Hi-C
Erdmann-Pham, D. D.; Batra, S. S.; Turkalo, T. K.; Durbin, J.; Blanchette, M.; Yeh, I.; Shain, H.; Bastian, B.; Song, Y. S.; Rokhsar, D. S.; Hockemeyer, D.
10.1101/2023.02.20.529175 — genomics — Posted on 2023-02-21
1160 Molecular Investigation of TSHR gene in Bangladeshi Congenital Hypothyroid patients
Begum, M. N.; Mahtarin, R.; Islam, M. T.; Ahmed, S.; Konika, T. K.; Mannoor, K.; Akhteruzzaman, S.; Qadri, F.
10.1101/2023.02.20.529210 — genetics — Posted on 2023-02-21
1164 rphenoscate: An R package for semantic-aware evolutionary analyses of anatomical traits
Porto, D.; Tarasov, S.; Charpentier, C.; Lapp, H.; Balhoff, J.; Vision, T.; Dahdul, W.; Mabee, P.; Uyeda, J.
10.1101/2023.02.19.528613 — evolutionary biology — Posted on 2023-02-21
1168 Host and viral determinants of airborne transmission of SARS-CoV-2 in the Syrian hamster
Port, J. R.; Morris, D. H.; Riopelle, J. C.; Yinda, C. K.; Avanzato, V. A.; Holbrook, M. G.; Bushmaker, T.; Schulz, J. E.; Saturday, T. A.; Barbian, K.; Russel, C. A.; Perry-Gottschalk, R.; Shaia, C. I.; Martens, C.; Lloyd-Smith, J. O.; Fischer, R. J.; Munster, V. J.
10.1101/2022.08.15.504010 — microbiology — Posted on 2023-02-21
1170 Butyrate, valerate, and niacin ameliorate anaphylaxis by suppressing IgE-dependent mast cell activation: Roles of GPR109A, PGE2, and epigenetic regulation
Nagata, K.; Ando, D.; Ashikari, T.; Ito, K.; Miura, R.; Fujigaki, I.; Ando, M.; Ito, N.; Kawazoe, H.; Iizuka, Y.; Inoue, M.; Yashiro, T.; Hachisu, M.; Kasakura, K.; Nishiyama, C.
10.1101/2023.02.19.529168 — immunology — Posted on 2023-02-21
1171 Kaempferol suppresses the activation of mast cells by modulating the expression of FcϵRI and SHIP1
Nagata, K.; Araumi, S.; Ando, D.; Ando, M.; Ito, N.; Ikeda, Y.; Takahashi, M.; Noguchi, S.; Yashiro, T.; Hachisu, M.; Nishiyama, C.
10.1101/2023.02.20.529186 — immunology — Posted on 2023-02-21
1172 HIV, asymptomatic STI, and the rectal mucosal immune environment among young men who have sex with men
Van Doren, V. E.; Smith, S. A.; Hu, Y.-J.; Tharp, G.; Bosinger, S.; Ackerley, C. G.; Murray, P. M.; Amara, R. R.; Amancha, P. K.; Arthur, R. A.; Johnston, H. R.; Kelley, C. F.
10.1101/2023.02.20.529184 — immunology — Posted on 2023-02-21
1174 Positive coping supports children's emotional wellness: Behavioral evidence and neuroendocrine mechanisms
Tian, T.; Chen, B.; Zhao, Y.; Gao, H.; Chen, M.; He, Y.; Xu, J.; Jiang, M.; Xiong, B.; Qin, S.
10.1101/2023.02.19.526965 — neuroscience — Posted on 2023-02-21
1176 UNRAVELing the synergistic effects of psilocybin and environment on brain-wide immediate early gene expression in mice
Rijsketic, D. R.; Casey, A. B.; Barbosa, D. A. N.; Zhang, X.; Hietamies, T. M.; Ramirez-Ovalle, G.; Pomrenze, M.; Halpern, C. H.; Williams, L. M.; Malenka, R. C.; Heifets, B. D.
10.1101/2023.02.19.528997 — neuroscience — Posted on 2023-02-21
1177 Astrocyte-like subpopulation of NG2 glia in the adult mouse cortex exhibits characteristics of neural progenitor cells and is capable of forming neuron-like cells after ischemic injury
Janeckova, L.; Knotek, T.; Kriska, J.; Hermanova, Z.; Kirdajova, D.; Kubovciak, J.; Berkova, L.; Tureckova, J.; Camacho Garcia, S.; Galuskova, K.; Kolar, M.; Anderova, M.; Korinek, V.
10.1101/2023.02.20.529180 — neuroscience — Posted on 2023-02-21
1179 Event-related modulation of alpha rhythm explains the auditory P300 evoked response in EEG
Studenova, A. A.; Forster, C.; Engemann, D. A.; Hensch, T.; Sander, C.; Mauche, N.; Hegerl, U.; Loeffler, M.; Villringer, A.; Nikulin, V. V.
10.1101/2023.02.20.529191 — neuroscience — Posted on 2023-02-21
1181 Associative memory retrieval modulates upcoming perceptual decisions.
Bornstein, A. M.; Aly, M.; Feng, S. F.; Turk-Browne, N. B.; Norman, K. A.; Cohen, J. D.
10.1101/186817 — neuroscience — Posted on 2023-02-21
1185 Citizenship status and career self-efficacy: An intersectional study of biomedical trainees in the United States
Chatterjee, D.; Nogueira, A. T.; Wefes, I.; Chalkley, R.; Sturzenegger Varvayanis, S.; Fuhrmann, C. N.; Varadarajan, J.; Jacob, G. A.; Gaines, C. H.; Hubbard, N. M.; Chaudhary, S.; Layton, R. L.
10.1101/2023.02.19.526477 — scientific communication and education — Posted on 2023-02-21
1186 Crane fly semiochemical overrules coordinate cyanobiont differentiation in Azolla ferns
Gungor, E.; Savary, J.; Adema, K.; Dijkhuizen, L. W.; Keilwagen, J.; Himmelbach, A.; Mascher, M.; Koppers, N.; Braeutigam, A.; van Hove, C.; Riant, O.; Nierzwicki-Bauer, S.; Schluepmann, H.
10.1101/2023.02.19.528669 — plant biology — Posted on 2023-02-21
1189 Molecular control of endurance training adaptation in mouse skeletal muscle
Furrer, R.; Heim, B.; Schmid, S.; Nordstrom, K. J. V.; Dilbaz, S.; Ritz, D.; Adak, V.; Steurer, S. A.; Walter, J.; Handschin, C.
10.1101/2023.02.18.529055 — physiology — Posted on 2023-02-21
1190 Atomistic molecular insight on Angiotensin-(1-7) inter-peptide interactions
Chi, L. A.; Asgharpour, S.; Blanco-Rodriguez, R.; Martinez-Archundia, M.
10.1101/2023.02.19.529149 — biophysics — Posted on 2023-02-21
1195 DeepHeme: A generalizable, bone marrow classifierwith hematopathologist-level performance
Goldgof, G.; Sun, S.; Cleaves, J.; Wang, L.; Lucas, F.; Brown, L.; Spectors, J.; Boiocchi, L.; Baik, J.; Zhu, M.; Ardon, O.; Lu, C.; Dogan, A.; Goldgof, D.; Carmichael, I.; Prakash, S.; Butte, A.
10.1101/2023.02.20.528987 — bioinformatics — Posted on 2023-02-21
1196 S1000: A better taxonomic name corpus for biomedical information extraction
Luoma, J.; Nastou, K. C.; Ohta, T.; Toivonen, H.; Pafilis, E.; Jensen, L. J.; Pyysalo, S.
10.1101/2023.02.20.528934 — bioinformatics — Posted on 2023-02-21
1200 Peptide ligands for the affinity purification of adeno-associated viruses from HEK 293 cell lysates
Chu, W.; Barbieri, E.; Prodromou, R.; Greback-Clarke, P.; Smith, W. K.; Moore, B. D.; Kilgore, R. E.; Cummings, C. L.; Pancorbo, J.; Gilleskie, G. L.; Daniele, M. A.; Menegatti, S.
10.1101/2023.02.19.529155 — bioengineering — Posted on 2023-02-21
1204 Characterization of the pearl millet cultivation environments in India: status and perspectives enabled by expanded data analytics and digital tools
Garin, V.; Choudhary, S.; Murugesan, T.; Kaliamoorthy, S.; Diancumba, M.; Hajjarpoor, A.; Satyavathi, T.; Gupta, S.; Kholova, J.
10.1101/2023.02.18.529051 — plant biology — Posted on 2023-02-21
1205 The distinctive mechanical and structural signatures of residual force enhancement in myofibers
Hessel, A. L.; Kuehn, M.; Palmer, B.; Nissen, D.; Mishra, D.; Joumaa, V.; Freundt, J.; Ma, W.; Nishikawa, K.; Irving, T.; Linke, W. A.
10.1101/2023.02.19.529125 — physiology — Posted on 2023-02-21
1208 Active mesh and neural network pipeline for cell aggregate segmentation
Smith, M. B.; Salbreux, G.; Dunsby, C.; Sparks, H.; Almagro, J.; Behrens, A.; Chaigne, A.
10.1101/2023.02.17.528925 — bioinformatics — Posted on 2023-02-21
1210 OME-Zarr: a cloud-optimized bioimaging file format with international community support
Moore, J.; Basurto-Lozada, D.; Besson, S.; Bogovic, J.; Brown, E. M.; Burel, J.-M.; de Medeiros, G.; Diel, E. E.; Gault, D.; Ghosh, S. S.; Gold, I.; Halchenko, Y. O.; Hartley, M.; Horsfall, D.; Keller, M. S.; Kittisopikul, M. S.; Kovacs, G.; Kuepcue Yoldas, A.; le Tournoulx de la Villegeorges, A.; Li, T.; Liberali, P.; Linkert, M.; Lindner, D.; Luethi, J.; Maitin-Shepard, J.; Manz, T.; McCormick, M.; Mohamed, K.; Moore, W.; oezdemir, B.; Pape, C.; Pelkmans, L.; Prete, M.; Pietzsch, T.; Preibisch, S.; Rzepka, N.; Stirling, D. R.; Striebel, J.; Tischer, C.; Toloudis, D.; Walczysko, P.; Watson, A
10.1101/2023.02.17.528834 — bioinformatics — Posted on 2023-02-21
1215 Three-Dimensional Bioconjugated Liquid-Like Solid (LLS) Enhance Characterization of Solid Tumor - Chimeric Antigen Receptor T cell Interactions
Nguyen, D. T.; Liu, R.; Ogando-Rivas, E.; Pepe, A.; Pedro, D.; Qdaisat, S.; Nguyen, T. Y. N.; Lavrador, J.; Golde, G.; Smolcheck, R.; Ligon, J.; Jin, L.; Tao, H.; Webber, A.; Phillpot, S.; Mitchell, D.; Sayour, E. J.; Huang, J.; Castillo, P.; Sawyer, W. G.
10.1101/2023.02.17.529033 — bioengineering — Posted on 2023-02-21
1219 BridgePRS: A powerful trans-ancestry Polygenic Risk Score method
Hoggart, C. J.; Choi, S. W.; Garcia-Gonzalez, J.; Souaiaia, T.; Preuss, M.; O'Reilly, P.
10.1101/2023.02.17.528938 — genetics — Posted on 2023-02-21
1221 Sarbecoviruses of British Horseshoe Bats; Sequence Variation and Epidemiology
Apaa, T.; Withers, A. J.; Staley, C. E.; Blanchard, A. M.; Bennett, M.; Bremner-Harrison, S.; Chadwick, E. A.; Hailer, F.; Harrison, S. W. R.; Loose, M.; Mathews, F.; Tarlinton, R. E.
10.1101/2023.02.14.528476 — microbiology — Posted on 2023-02-21
1229 Scorpionfish BPI is highly active against multiple drug-resistant Pseudomonas aeruginosa isolates from cystic fibrosis patients
Holzinger, J. M.; Toelge, M.; Werner, M.; Ederer, K. U.; Siegmund, H. I.; Peterhoff, D.; Blaas, S.; Gisch, N.; Brochhausen-Delius, C.; Gessner, A.; Bülow, S.
10.1101/2023.02.19.529133 — microbiology — Posted on 2023-02-21
1230 Substrate evaporation drives collective construction in termites
Facchini, G.; Rathery, A.; Douady, S.; Sillam-Dusses, D.; Perna, A.
10.1101/2023.02.17.528984 — biophysics — Posted on 2023-02-21
1233 Barley shows reduced Fusarium Head Blight under drought and modular expression of differential expressed genes under combined stress
Hoheneder, F.; Steidele, C. E.; Messerer, M.; Mayer, K.; Koehler, N.; Wurmser, C.; Hess, M.; Gigl, M.; Dawid, C.; Stam, R.; Hueckelhoven, R.
10.1101/2023.02.15.528674 — plant biology — Posted on 2023-02-21
1237 Recruitment of the SNX17-Retriever recycling pathway regulates synaptic function and plasticity.
Rivero-Rios, P.; Tsukahara, T.; Uygun, T.; Chen, A.; Chavis, G. D.; Giridharan, S. S. P.; Iwase, S.; Sutton, M. A.; Weisman, L. S.
10.1101/2023.02.20.529299 — cell biology — Posted on 2023-02-21
1239 Cerebellar Morphological Differences in Bipolar Disorder Type I
Harmata, G. I. S.; Barsotti, E. J.; Casten, L. G.; Fiedorowicz, J. G.; Williams, A. J.; Shaffer, J. J.; Richards, J. G.; Sathyaputri, L.; Schmitz, S. L.; Christensen, G. E.; Long, J. D.; Gaine, M. E.; Xu, J.; Michaelson, J. J.; Wemmie, J. A.; Magnotta, V. A.
10.1101/2023.02.20.528549 — neuroscience — Posted on 2023-02-21
1241 The N terminus-only (trans) function of the Adhesion GPCR Latrophilin-1 controls multiple processes in reproduction of C. elegans
Matus, D.; Gross, V. E.; Fiedler, F.; Post, W. B.; Knierim, A. B.; Schon, J. L.; Schoneberg, T.; Promel, S.
10.1101/2023.02.18.529090 — physiology — Posted on 2023-02-21
1242 A standardized and reproducible workflow for membrane glass slides in routine histology and spatial proteomics
Nordmann, T. M.; Schweizer, L.; Metousis, A.; Thielert, M.; Rodriguez, E.; Rahbek-Gjerdrum, L. M.; Stadler, P.-C.; Bzorek, M.; Mund, A.; Rosenberger, F. A.; Mann, M.
10.1101/2023.02.20.529255 — pathology — Posted on 2023-02-21
1244 Geometry-preserving Expansion Microscopy microplates enable high fidelity nanoscale distortion mapping
Seehra, R. S.; Allouis, B. H. K.; Sheard, T. M. D.; Spencer, M. E.; Shakespeare, T.; Cadby, A. J.; Jayasinghe, I.
10.1101/2023.02.20.529230 — biophysics — Posted on 2023-02-21
1246 Cysteine-Rich Intestinal Protein 1 is a Novel Surface Marker for Myometrial Stem/Progenitor Cells.
Paul, E. N.; Carpenter, T. J.; Fitch, S.; Sheridan, R.; Lau, K. H.; Arora, R.; Teixeira, J. M.
10.1101/2023.02.20.529273 — developmental biology — Posted on 2023-02-21
1247 FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity
Wieder, N.; Coraor Fried, J. M.; Kim, C.; Sidhom, E.-H.; Brown, M. R.; Marshall, J. L.; Arevalo, C.; Dvela-Levitt, M.; Kost-Alimova, M.; Sieber, J.; Gabriel, K. R.; Pacheco, J.; Clish, C. B.; Abbasi, H. S.; Singh, S.; Rutter, J.; Therrien, M.; Yoon, H.; Lai, Z. W.; Baublis, A.; Subramanian, R.; Devkota, R.; Small, J.; Sreekanth, V.; Han, M.; Lim, D.; Carpenter, A. E.; Flannick, J. A.; Finucane, H.; Haigis, M. C.; Claussnitzer, M.; Sheu, E.; Stevens, B.; Wagner, B.; Choudhary, A.; Shaw, J. L.; Pablo, J. L.; Greka, A.
10.1101/2023.02.19.529127 — cell biology — Posted on 2023-02-20
1248 Distinct mobility patterns of BRCA2 molecules at DNA damage sites
Paul, M. W.; Aaron, J.; Wait, E.; van Genderen, R. M.; Smal, I.; Chew, T.-L.; Kanaar, R.; Wyman, C.
10.1101/2023.02.20.527475 — cell biology — Posted on 2023-02-20
1253 A Sweeter Future: Using protein language models for exploring sweeter brazzein homologs
Chua, B. N.; Guo, W. M.; Wong, H. T.; Ow, D. S.-W.; Ho, P. L.; Koh, W.; Koay, A.; Wong, F. T.
10.1101/2023.02.20.529172 — synthetic biology — Posted on 2023-02-20
1260 Spatially aware deep learning reveals tumor heterogeneity patterns that encode distinct kidney cancer states
Nyman, J.; Denize, T.; Bakouny, Z.; Labaki, C.; Titchen, B. M.; Bi, K.; Hari, S. N.; Rosenthal, J.; Mehta, N.; Jiang, B.; Sharma, B.; Felt, K.; Umeton, R.; Braun, D. A.; Rodig, S.; Choueiri, T. K.; Signoretti, S.; Van Allen, E. M.
10.1101/2023.01.18.524545 — cancer biology — Posted on 2023-02-20
1265 Domestication of different varieties in the cheese-making fungus Geotrichum candidum
Bennetot, B.; Vernadet, J. P.; Perkins, V.; Hautefeuille, S.; Rodriguez de la Vega, R. C.; O'Donnell, S.; Snirc, A.; Grondin, C.; Lessard, M.-H.; Peron, A.-C.; Labrie, S.; Landaud, S.; Giraud, T.; Ropars, J.
10.1101/2022.05.17.492043 — genetics — Posted on 2023-02-20
1266 Crosstalk between Rac and Rho GTPase activity mediated by Arhgef11 and Arhgef12 coordinates cell protrusion-retraction cycles.
Nanda, S.; Calderon, A.; Duong, T.-T.; Koch, J.; Sachan, A.; Xin, X.; Solouk, D.; Wu, Y.-W.; Nalbant, P.; Dehmelt, L.
10.1101/2023.02.20.529203 — cell biology — Posted on 2023-02-20
1267 Enterovirus Evolution Reveals the Mechanism of an RNA-Targeted Antiviral and Determinants of Viral Replication
Davila-Calderon, J.; Li, M.-L.; Penumutchu, S.; Haddad, C.; Malcolm, L.; Hargrove, A. E.; Brewer, G.; Tolbert, B. S.
10.1101/2023.02.20.529064 — molecular biology — Posted on 2023-02-20
1269 A global Corynebacterium diphtheriae genomic framework sheds light on current diphtheria reemergence
Hennart, M.; Crestani, C.; Bridel, S.; Armatys, N.; Bremont, S.; Carmi-Leroy, A.; Landier, A.; Passet, V.; Fonteneau, L.; Vaux, S.; Toubiana, J.; Badell-Ocando, E.; Brisse, S.
10.1101/2023.02.20.529124 — microbiology — Posted on 2023-02-20
1271 Towards estimating the number of strains that make up a natural bacterial population
Viver, T.; Conrad, R. E.; Rodriguez-R, L. M.; Ramirez, A. S.; Venter, S. N.; Rocha-Cardenas, J.; Segura, M. L.; Amann, R.; Konstantinidis, K. T.; Rossello-Mora, R.
10.1101/2023.02.20.529252 — microbiology — Posted on 2023-02-20
1272 A novel order-level lineage of ammonia-oxidizing Thaumarchaeota is widespread in marine and terrestrial environments
Zheng, Y.; Wang, B.; Gao, P.; Yang, Y.; Su, X.; Ning, D.; Tao, Q.; Zhao, F.; Wang, D.; Zhang, Y.; Li, M.; Winkler, M.-K. H.; Ingalls, A. E.; Zhou, J.; Zhang, C.; Stahl, D. A.; Jiang, J.; Martens-Habbena, W.; Qin, W.
10.1101/2023.02.17.529030 — microbiology — Posted on 2023-02-20
1274 Functional antagonistic interactions and genomic insights into the biosynthetic potential of human gut-derived microbiota
Hussain, A.; Patwekar, U.; Mongad, D. S.; Nimonkar, Y.; Mundhe, S.; Paul, D.; Prakash, O.; Shouche, Y. S.
10.1101/2023.02.20.529173 — microbiology — Posted on 2023-02-20
1278 FLAgellum Member 8 modulates extravasation and extravascular distribution of African trypanosomes.
Alvarez, E. C.; Ngoune, J. M. T.; Cooper, A.; Travaille, C.; Crouzols, A.; MacLeod, A.; Rotureau, B.
10.1101/2023.02.20.529185 — microbiology — Posted on 2023-02-20
1279 CelltypeR: A flow cytometry pipeline to annotate, characterize and isolate single cells from brain organoids
Thomas, R. A.; Sirois, J.; Li, S.; Gestin, A.; Piscopo, V. E.; Lepine, P.; Mathur, M.; Chen, C. X. Q.; Soubannier, V.; Goldsmith, T. M.; Fawaz, L.; Durcan, T. M.; Fon, E. A.
10.1101/2022.11.11.516066 — neuroscience — Posted on 2023-02-20
1280 Is resting state fMRI better than individual characteristics at predicting cognition?
Omidvarnia, A.; Sasse, L.; Larabi, D. I.; Raimondo, F.; Hoffstaedter, F.; Kasper, J.; Dukart, J.; Petersen, M.; Cheng, B.; Thomalla, G.; Eickhoff, S. B.; Patil, K. R.
10.1101/2023.02.18.529076 — neuroscience — Posted on 2023-02-20
1281 Highly efficient induction of functionally mature excitatory neurons from feeder-free human ES/iPS cells
Zhou, Z.; Kakegawa, W.; Fujimori, K.; Sho, M.; Shimamura, R.; Supakul, S.; Yoshimatsu, S.; Kohyama, J.; Yuzaki, M.; Okano, H.
10.1101/2023.02.10.528087 — neuroscience — Posted on 2023-02-20
1282 High-throughput sequencing of macaque basolateral amygdala projections reveals dissociable connectional motifs with frontal cortex
Zeisler, Z. R.; London, L.; Janssen, W. G.; Fredericks, J. M.; Elorette, C.; Fujimoto, A.; Zhan, H.; Russ, B. E.; Clem, R. L.; Hof, P. R.; Stoll, F. M.; Rudebeck, P. H.
10.1101/2023.01.18.524407 — neuroscience — Posted on 2023-02-20
1283 Lidocaine Induces Apoptosis in Head and Neck Squamous Cell Carcinoma Cells Through Activation of Bitter Taste Receptor T2R14
Miller, Z. A.; Jolivert, J. F.; Ma, R. Z.; Muthuswami, S.; Mueller, A.; McMahon, D. B.; Carey, R. M.; Lee, R. J.
10.1101/2022.11.22.517413 — cancer biology — Posted on 2023-02-20
1284 Multidimensional Characterization of Soft-Tissue Sarcomas with FUS-TFCP2 or EWSR1-TFCP2 Fusions
Schopf, J.; Uhrig, S.; Heilig, C. E.; Lee, K.-S.; Walther, T.; Carazzato, A.; Dobberkau, A. M.; Weichenhan, D.; Plass, C.; Hartmann, M.; Diwan, G. D.; Carrero, Z.; Ball, C. R.; Hohl, T.; Kindler, T.; Rudolph-Hahnel, P.; Nilsson, A.; Ora, I.; Imle, R.; Banito, A.; Russell, R. B.; Jones, B. C.; Lipka, D.; Glimm, H.; Hubschmann, D.; Hartmann, W.; Frohling, S.; Scholl, C.
10.1101/2023.02.19.528670 — cancer biology — Posted on 2023-02-20
1285 TMvisDB: resource for transmembrane protein annotation and 3D visualization
Marquet, C.; Grekova, A.; Houri, L.; Bernhofer, M.; Jimenez-Soto, L.; Karl, T.; Heinzinger, M.; Dallago, C.; Rost, B.
10.1101/2022.11.30.518551 — bioinformatics — Posted on 2023-02-20
1286 A robust Platform for Integrative Spatial Multi-omics Analysis to Map Immune Responses to SARS-CoV-2 infection in Lung Tissues
Tan, X.; Grice, L. F.; Tran, M.; Mulay, O.; Monkman, J.; Blick, T.; Vo, T. Q. A.; Almeida, A. C. S. F.; Junior, J. d. S. M.; de Moura, K. F.; Machado-Souza, C.; Souza-Fonseca-Guimaraes, P.; Baena, C. P.; de Noronha, L.; Guimaraes, F. S. F.; Luu, H. N.; Drennon, T.; Williams, S.; Stern, J.; Uytingco, C.; Cooper, C.; Short, K.; Belz, G.; Souza-Fonseca-Guimaraes, F.; Kulasinghe, A.; Nguyen, Q.
10.1101/2023.02.19.529128 — bioinformatics — Posted on 2023-02-20
1287 Near-atomic resolution reconstructions from in situ revitrified cryo samples
Bongiovanni, G.; Harder, O. F.; Voss, J. M.; Drabbels, M.; Lorenz, U. J.
10.1101/2023.02.20.529238 — biochemistry — Posted on 2023-02-20
1289 Genetic consequences of effective and suboptimal dosing with mutagenic drugs in a hamster model of SARS-CoV-2 infection
Illingworth, C.; Guerra-Assuncao, J. A.; Gregg, S.; Charles, O. J.; Pang, J.; Roy, S.; Abdelnabi, R.; Neyts, J.; Breuer, J.
10.1101/2023.02.20.529243 — evolutionary biology — Posted on 2023-02-20
1291 Single Cell Transcriptomics identifies a WNT7A-FZD5 Signaling Axis that maintains Fallopian Tube Stem Cells in Patient-derived Organoids
Alsaadi, A.; Artibani, M.; Hu, Z.; Wietek, N.; Morotti, M.; Gonzalez, L. S.; Alazzam, M.; Jiang, J.; Abdul, B.; Soleymani majd, H.; Blazer, L. L.; Adams, J. J.; Silvestri, F.; Sidhu, S.; Brugge, J. S.; Ahmed, A. A.
10.1101/2022.08.02.502319 — developmental biology — Posted on 2023-02-20
1292 Gli2 and Gli3 Regulate Horizontal Basal Cell-Mediated Regeneration of the Olfactory Epithelium
Shirazyan, A.; Park, H.; Joiner, A. M.; Ra, J.; Kim, M. S.; Kumari, A.; Franks, N. E.; PENG, T.; Bradley, R. M.; Mistretta, C. M.; Dlugosz, A. A.; Allen, B. L.
10.1101/2022.08.29.504820 — cell biology — Posted on 2023-02-20
1293 Imprinted cell memory in glycogen storage disorder 1a
Sprecher, U.; Dsouza, J.; Mishra, K.; Miliano, A. C.; Mithieux, G.; Rajas, F.; Avraham, S.; Anikster, Y.; Kakhlon, O.; Weil, M.
10.1101/2023.02.20.529109 — molecular biology — Posted on 2023-02-20
1295 Validation of the association between MRI and gene signatures in facioscapulohumeral dystrophy muscle: implications for clinical trial design
Wong, C.-J.; Friedman, S. D.; Snider, L.; Bennett, S. R.; Jones, T. I.; Jones, P. L.; Shaw, D. W.; Blemker, S. S.; Riem, L.; DuCharme, O.; Lemmers, R. J.; van der Maarel, S. M.; Wang, L. H.; Tawil, R.; Statland, J. M.; Tapscott, S. J.
10.1101/2023.02.20.529303 — molecular biology — Posted on 2023-02-20
1299 Antibody-mediated cell entry of SARS-CoV-2
Kibria, M. G.; Lavine, C. L.; Tang, W.; Wang, S.; Gao, H.; Shi, W.; Zhu, H.; Voyer, J.; Rits-Volloch, S.; Keerti, F.; Bi, C.; Peng, H.; Wesemann, D.; Lu, J.; Xie, H.; Seaman, M. S.; Chen, B.
10.1101/2023.02.20.529249 — microbiology — Posted on 2023-02-20
1300 Bovine milk glycoproteins inhibit SARS-CoV-2 and influenza virus co-infection
Yu, H.; Chen, W.; Shu, J.; Wu, X.; Quan, J.; Cheng, H.; Bao, X.; Wu, D.; Wang, X.; Li, Z.
10.1101/2023.02.20.529234 — microbiology — Posted on 2023-02-20
1301 Spatial Tuning of Alpha Oscillations in Human Visual Cortex
Yuasa, K.; Groen, I. I. A.; Piantoni, G.; Montenegro, S.; Flinker, A.; Devore, S.; Devinsky, O.; Doyle, W.; Dugan, P.; Friedman, D.; Ramsey, N.; Petridou, N.; Winawer, J.
10.1101/2023.02.11.528137 — neuroscience — Posted on 2023-02-20
1302 Tetraose steroidal glycoalkaloids from potato can provide complete protection against fungi and insects
Wolters, P. J.; Wouters, D.; Tikunov, Y. M.; Ayilalath, S.; Kodde, L. P.; Strijker, M.; Caarls, L.; Visser, R. G. F.; Vleeshouwers, V. G. A. A.
10.1101/2022.09.28.509958 — plant biology — Posted on 2023-02-20
1308 Feature selection and aggregation for antibiotic resistance GWAS in Mycobacterium tuberculosis: a comparative study.
Reshetnikov, K. O.; Bykova, D. I.; Kuleshov, K. V.; Chukreev, K.; Guguchkin, E. P.; Akimkin, V. G.; Neverov, A. D.; Fedonin, G. G.
10.1101/2022.03.16.484601 — bioinformatics — Posted on 2023-02-20
1313 SARS-CoV-2 Protein Nsp2 Stimulates Translation Under Normal and Hypoxic Conditions
Korneeva, N.; Khalil, M. I.; Ghosh, I.; Fan, R.; Arnold, T.; De Benedetti, A.
10.1101/2022.09.13.507829 — physiology — Posted on 2023-02-20
1315 Regulatory T Cell-like Response to SARS-CoV-2 in Jamaican Fruit Bats Transduced with Human ACE2
Burke, B.; Rocha, S.; Zhan, S.; Eckley, M.; Reasoner, C.; Addetia, A.; Lewis, J.; Fagre, A. C.; Charley, P.; Richt, J. A.; Weiss, S. R.; Tjalkens, R.; Veesler, D.; Aboellail, T.; Schountz, T.
10.1101/2023.02.13.528205 — microbiology — Posted on 2023-02-20
1319 Folate-based in vivo reprogramming of dentate gyrus improves cognitive function in old mice
Anton Fernandez, A.; Cuadros, R.; Peinado-Cahuchola, R.; Hernandez, F.; Avila, J.
10.1101/2023.02.01.526619 — neuroscience — Posted on 2023-02-20
1320 Long-term near-continuous recording with Neuropixels probes in healthy and epileptic rats
Ghestem, A.; Pompili, M. N.; Dipper-Wawra, M.; Quilichini, P. P.; Bernard, C.; Ferraris, M.
10.1101/2023.02.16.528689 — neuroscience — Posted on 2023-02-20
1323 On the reproductive mechanisms of protocells
Kanaparthi, D.; Lampe, M.; Krohn, J. H.; Hildebrand, F.; Boesen, T.; Klingl, A.; Phapale, P.; Lueders, T.
10.1101/2021.11.25.470039 — evolutionary biology — Posted on 2023-02-20
1324 Sex-specific declines in cholinergic-targeting tRNA fragments in the nucleus accumbens in Alzheimer's disease
Shulman, D.; Dubnov, S.; Zorbaz, T.; Madrer, N.; Paldor, I.; Bennett, D. A.; Seshadri, S.; Mufson, E. J.; Greenberg, D.; Loewenstein, Y.; Soreq, H. S.
10.1101/2023.02.08.527612 — bioinformatics — Posted on 2023-02-20
1325 SOS1 and KSR1 modulate MEK inhibitor responsiveness to target resistant cell populations based on PI3K and KRAS mutation status
Daley, B.; Vieira, H. M.; Rao, C.; Hughes, J. M.; Huisman, D. H.; Chatterjee, D.; Sealover, N. E.; Cox, K.; Askew, J. W.; Beckley, Z. M.; Svoboda, R. A.; Fisher, K. W.; Lewis, R. E.; Kortum, R. L.
10.1101/2022.12.06.519395 — cancer biology — Posted on 2023-02-19
1330 Identification of major quantitative trait loci for parthenocarpic ability in East Asian melon
Yoshioka, Y.; Nashiki, A.; Zaelani, A.; Isobe, S.; Shirasawa, K.; Shimomura, K.; Ohyama, A.
10.1101/2023.02.16.528896 — plant biology — Posted on 2023-02-19
1331 Delayed development of basal spikelets in wheat explains their increased floret abortion and rudimentary nature
Backhaus, A. E.; Griffiths, C.; Vergara-Cruces, A.; Simmonds, J.; Lee, R.; Morris, R. J.; Uauy, C.
10.1101/2023.02.17.528935 — plant biology — Posted on 2023-02-19
1332 Extensive profiling of histidine-containing dipeptides reveals species-specific distribution and metabolism in mice, rats and humans
Van der Stede, T.; Spaas, J.; de Jager, S.; De Brandt, J.; Hansen, C.; Vercammen, B.; De Baere, S.; Croubels, S.; Van Thienen, R.; Verboven, K.; Hansen, D.; Bove, T.; Lapauw, B.; Van Praet, C.; Decaestecker, K.; Vanaudenaerde, B.; Eijnde, B. O.; Gliemann, L.; Hellsten, Y.; Derave, W.
10.1101/2023.02.16.528841 — physiology — Posted on 2023-02-19
1334 Rapid Molecular Mechanotyping with Microfluidic Force Spectroscopy
van Galen, M.; Bok, A.; Peshkovsky, T.; van der Gucht, J.; Albada, B.; Sprakel, J.
10.1101/2023.02.17.528971 — biophysics — Posted on 2023-02-19
1336 Isolated nuclei from frozen tissue are the superior source for single cell RNA-seq compared with whole cells.
Jiang, A.; Lehnert, K.; Reid, S. J.; Handley, R. R.; Jacobsen, J. C.; Rudiger, S. R.; McLaughlan, C.; Verma, P.; Bawden, S.; Snell, R. G.
10.1101/2023.02.19.529150 — genomics — Posted on 2023-02-19
1337 The drivers of dark diversity in the Scandinavian tundra are metric-dependent
Hostens, L.; Van Meerbeek, K.; Wiegmans, D.; Larson, K.; Lenoir, J.; Clavel, J.; Wedegartner, R. E. M.; Piree, A.; Nijs, I.; Lembrechts, J. J.
10.1101/2023.02.17.528269 — ecology — Posted on 2023-02-19
1340 Evolution of promoter-proximal pausing enabled a new layer of transcription control
Chivu, A. G.; Abuhashem, A.; Barshad, G.; Rice, E. J.; Leger, M. M.; Vill, A. C.; Wong, W.; Brady, R.; Smith, J.; Wikramanayake, A.; Arenas-Mena, C.; Brito, I. L.; Ruiz-Trillo, I.; Hadjantonakis, A.-K.; Lis, J.; Lewis, J. J.; Danko, C. G.
10.1101/2023.02.19.529146 — evolutionary biology — Posted on 2023-02-19
1344 The Regulation of Nucleic Acid Vaccine Responses by the Microbiome
Johnson, A. M. F.; Hager, K.; Alameh, M.-G.; Van, P.; Potchen, N.; Mayer-Blackwell, K.; Fiore-Gartland, A.; Minot, S.; Lin, P. J. C.; Tam, Y. K.; Weissman, D.; Kublin, J. G.
10.1101/2023.02.18.529093 — immunology — Posted on 2023-02-19
1345 Alternative splicing of its 5' untranslated region controls CD20 mRNA translation and enables resistance to CD20-directed immunotherapies
Ang, Z.; Hayer, K. E.; Torres Diz, M.; Schmidt, C.; Zheng, S.; Xu, F.; Falkenstein, C. D.; Loftus, J. P.; Yang, S. Y.; Asnani, M.; Pillai, V.; Chong, E.; Li, M. M.; Tasian, S. K.; Barash, Y.; Schuster, S. J.; Thomas-Tikhonenko, A.
10.1101/2023.02.19.529123 — immunology — Posted on 2023-02-19
1347 A pillar/perfusion plate enhances cell growth, reproducibility, throughput, and user friendliness in dynamic 3D cell culture
Lekkala, V. K. R.; Kang, S.-Y.; Liu, J.; Shrestha, S.; Acharya, P.; Joshi, P.; Zolfaghar, M.; Lee, M.; Jamdagneya, P.; Pagnis, S.; Kundi, A.; Kabbur, S.; Kim, U. T.; Yang, Y.; Lee, M.-Y.
10.1101/2023.02.16.528892 — bioengineering — Posted on 2023-02-19
1349 Small-molecule targeting of GPCR-independent non-canonical G protein signaling inhibits cancer progression
Zhao, J.; DiGiacomo, V.; Ferreras-Gutierrez, M.; Dastjerdi, S.; de Opakua, A. I.; Park, J.-C.; Luebbers, A.; Chen, Q.; Beeler, A.; Blanco, F. J.; Garcia-Marcos, M.
10.1101/2023.02.18.529092 — biochemistry — Posted on 2023-02-19
1350 Spatial and social structure of rewilded laboratory mice
Vogt, C. C.; Zipple, M. N.; Sprockett, D. D.; Miller, C. H.; Hardy, S. X.; Arthur, M. K.; Greenstein, A. M.; Colvin, M. S.; Michel, L. M.; Moeller, A. H.; Sheehan, M. J.
10.1101/2022.04.19.488643 — animal behavior and cognition — Posted on 2023-02-19
1352 Single-strand mismatch and damage patterns revealed by single-molecule DNA sequencing
Liu, M. H.; Costa, B.; Choi, U.; Bandler, R.; Lassen, E. M.; Gronska-Peski, M.; Schwing, A. K.; Murphy, Z. R.; Rosenkjaer, D.; Picciotto, S.; Bianchi, V.; Stengs, L.; Edwards, M.; Loh, C.; Truong, T. K.; Brand, R.; Pastinen, T.; Wagner, J. R.; Skytte, A.-B.; Tabori, U.; Shoag, J. E.; Evrony, G. D.
10.1101/2023.02.19.526140 — genomics — Posted on 2023-02-19
1353 Genetic investigation of honeybee populations in Kazakhstan
Gritsenko, D.; Temirbayeva, K.; Taskuzhina, A.; Kostyukova, V.; Pozharskiy, A.; Khusnitdinova, M.; Krupskiy, O.; Mayer, A.; Nuralieva, U.
10.1101/2023.02.08.527617 — genetics — Posted on 2023-02-19
1355 Marginal specificity in protein interactions constrains evolution
Ghose, D. A.; Przydzial, K. E.; Mahoney, E. M.; Keating, A. E.; Laub, M. T.
10.1101/2023.02.18.529082 — evolutionary biology — Posted on 2023-02-19
1357 Touch receptor end-organ innervation and function requires sensory expression of the transcription factor Meis2.
Desiderio, S.; Schwaller, F.; Tartour, K.; Padmanabhan, K.; Lewin, G. R.; Carroll, P.; Marmigere, F.
10.1101/2022.04.28.489889 — developmental biology — Posted on 2023-02-19
1359 Cardiac Development Long non-coding RNA (CARDEL) is activated during human heart development and contributes to cardiac specification and homeostasis
Pereira, I. T.; Gomes-Junior, R.; Hansel-Frose, A.; Liu, M.; Soliman, H. A. N.; Chan, S. S. K.; Dudley, S. C.; Kyba, M.; Dallagiovanna, B.
10.1101/2023.02.19.529122 — developmental biology — Posted on 2023-02-19
1360 Transcription factor FOXM1 specifies the loading of chromatin DNA to extracellular vesicles
Zhang, Y.; Ding, N.; Li, Y.; Zhao, X.; Yang, S.; Fu, P.; Peng, Y.; Cheng, H.; Ouyang, M.; Wang, R.; Wang, Y.; Liu, H.; Chen, Y.; Huang, X.; Yu, L.; Tan, Y.
10.1101/2022.01.27.477315 — cell biology — Posted on 2023-02-19
1361 Targeting RBM10 deficiency in lung adenocarcinoma
Machour, F. E.; Abu-Zhayia, E.; Kamar, J.; Barisaac, A. S.; Simon, I.; Ayoub, N.
10.1101/2023.02.19.529108 — molecular biology — Posted on 2023-02-19
1362 Precise and efficient C-to-U RNA Base Editing with SNAP-CDAR-S
Latifi, N.; Mack, A. M.; Tellioglu, I.; Di Giorgio, S.; Stafforst, T.
10.1101/2023.02.17.528953 — molecular biology — Posted on 2023-02-19
1363 Application of nanotags and nanobodies for live cell single-molecule imaging of the Z-ring in Escherichia coli
Westlund, E.; Bergenstrale, A.; Pokhrel, A.; Skoglund, U.; Chan, H.; Daley, D. O.; Söderström, B.
10.1101/2023.02.19.529144 — microbiology — Posted on 2023-02-19
1364 Aerobic anoxygenic phototrophic bacteria are ubiquitous in phyllo- and endosphere microbiomes of boreal and subarctic plants
Nissinen, R. M.; Franz, O.; Kovanen, S.; Mäkelä, M.; Kraft, V.; Ketola, K.; Liukkonen, A.; Heikkilä-Huhta, K.; Häkkänen, H.; Ihalainen, J.
10.1101/2023.02.19.529139 — microbiology — Posted on 2023-02-19
1365 Co-localization of antibiotic resistance genes is widespread in the infant gut microbiome and associates with an immature gut microbial composition
Li, X.; Brejnrod, A.; Trivedi, U.; Russel, J.; Thorsen, J.; Shah, S. A.; Vestergaard, G. A.; Rasmussen, M. A.; Nesme, J.; Bisgaard, H.; Stokholm, J.; Sorensen, S. J.
10.1101/2023.02.19.525876 — microbiology — Posted on 2023-02-19
1367 Macrophage-targeted lipid nanoparticle delivery of microRNA-146a to mitigate hemorrhagic shock-induced acute respiratory distress syndrome
Fei, Q.; Shalosky, E. M.; Barnes, R.; Shukla, V. C.; Ballinger, M. N.; Farkas, L.; Lee, R. J.; Ghadiali, S. N.; Englert, J. A.
10.1101/2023.02.17.529007 — pharmacology and toxicology — Posted on 2023-02-19
1368 Acetylation-dependent coupling between G6PD activity and apoptotic signaling
Wu, F.; Muskat, N. H.; Dvilansky, I.; Koren, O.; Shahar, A.; Gazit, R.; Elia, N.; Arbely, E.
10.1101/2023.02.19.529048 — biochemistry — Posted on 2023-02-19
1373 Novel Evoked Synaptic Activity Potentials (ESAPs) elicited by Spinal Cord Stimulation
Sharma, M.; Bhaskar, V.; Yang, L.; FallahRad, M.; Gebodh, N.; Zhang, T.; Esteller, R.; Martin, J.; Bikson, M.
10.1101/2023.02.18.528981 — neuroscience — Posted on 2023-02-19
1374 Reorganization of corticospinal projections after prominent recovery of finger dexterity from partial spinal cord injury in macaque monkeys
Sawada, M.; Yoshino-Saito, K.; Ninomiya, T.; Oishi, T.; Yamashita, T.; Onoe, H.; Takada, M.; Nishimura, Y.; Isa, T.
10.1101/2023.02.19.529046 — neuroscience — Posted on 2023-02-19
1375 Is resting state fMRI better than individual characteristics at predicting cognition?
Omidvarnia, A.; Sasse, L.; Larabi, D. I.; Raimondo, F.; Hoffstaedter, F.; Kasper, J.; Dukart, J.; Petersen, M.; Cheng, B.; Thomalla, G.; Eickhoff, S.; Patil, K.
10.1101/2023.02.18.529076 — neuroscience — Posted on 2023-02-19
1378 Protective effect of plasma neutralization from prior SARS-CoV-2 Omicron infection against BA.5 subvariant symptomatic reinfection
Chen, X.; Xu, Y.; Xie, Y.; Song, W.; Hu, Y.; Yisimayi, A.; Shao, F.; Geng, L.; Wang, Y.; Gao, H.; Shi, Y.; Zhang, S.; Jin, R.; Shen, Z.; Cao, Y. R.
10.1101/2023.02.14.527605 — immunology — Posted on 2023-02-19
1379 Cortical activity emerges in region-specific patterns during early brain development
Suarez, R.; Bluett, T.; McCullough, M.; Avitan, L.; Black, D.; Paolino, A.; Fenlon, L.; Goodhill, G.; Richards, L. J.
10.1101/2023.02.18.529078 — neuroscience — Posted on 2023-02-19
1380 Tau expression and phosphorylation in enteroendocrine cells
Chapelet, G.; Beguin, N.; Castellano, B.; Grit, I.; Oullier, T.; Neunlist, M.; Blottiere, H.; Rolli-Derkinderen, M.; Le Drean, G.; Derkinderen, P.
10.1101/2023.02.19.528206 — neuroscience — Posted on 2023-02-19
1383 Spenito-dependent metabolic sexual dimorphism intrinsic to fat storage cells
Diaz, A. V.; Matheny, T.; Stephenson, D.; Nemkov, T.; D'Alessandro, A.; Reis, T.
10.1101/2023.02.17.528952 — genetics — Posted on 2023-02-19
1385 A novel order-level lineage of ammonia-oxidizing Thaumarchaeota is widespread in marine and terrestrial environments
Zheng, Y.; Wang, B.; Gao, P.; Yang, Y.; Su, X.; Ning, D.; Tao, Q.; Zhao, F.; Wang, D.; Zhang, Y.; Li, M.; Winkler, M.-K. H.; Ingalls, A. E.; Zhou, J.; Zhang, C.; Stahl, D. A.; Jiang, J.; Martens-Habbena, W.; Qin, W.
10.1101/2023.02.17.529030 — microbiology — Posted on 2023-02-19
1386 Long-term near-continuous recording with Neuropixels probes in healthy and epileptic rats
Ghestem, A.; Pompili, M. N.; Dipper-Wawra, M.; Quilichini, P. P.; Bernard, C.; Ferraris, M.
10.1101/2023.02.16.528689 — neuroscience — Posted on 2023-02-19
1388 IGF2BP2 is Induced by Stress in the Heart and Mediates Dilated Cardiomyopathy
Krumbein, M.; Oberman, F.; Cinnamon, Y.; Golomb, M.; May, D.; Vainer, G.; Belzer, V.; Meir, K.; Fridman, I.; Haybaeck, J.; Poelzl, G.; Kehat, I.; Beeri, R.; Kessler, S.; Yisraeli, J. K.
10.1101/2022.11.03.515033 — cell biology — Posted on 2023-02-19
1392 Pulmonary osteoclast-like cells in silica induced pulmonary fibrosis
Hasegawa, Y.; Franks, J. M.; Tanaka, Y.; Uehara, Y.; Read, D. F.; Williams, C.; Srivatsan, S.; Pitstick, L. B.; Nikolaidis, N. M.; Shaver, C. M.; Wu, H.; Gardner, J. C.; Osterburg, A. R.; Yu, J. J.; Kopras, E. J.; Teitelbaum, S. L.; Wikenheiser-Brokamp, K. A.; Trapnell, C.; McCormack, F. X.
10.1101/2023.02.17.528996 — pathology — Posted on 2023-02-18
1393 mRNA interactions with disordered regions control protein activity
Luo, Y.; Pratihar, S.; Horste, E.; Mitschka, S.; Mey, A.; Al-Hashimi, H. M.; Mayr, C.
10.1101/2023.02.18.529068 — molecular biology — Posted on 2023-02-18
1399 Diversity of function and higher-order structure within HWE sensor histidine kinases
Dikiy, I.; Swingle, D.; Toy, K.; Edupuganti, U. R.; Rivera-Cancel, G.; Gardner, K. H.
10.1101/2020.07.08.194225 — biochemistry — Posted on 2023-02-18
1400 A metal ion-dependent mechanism of RAD51 nucleoprotein filament disassembly
Appleby, R.; Bollschweiler, D.; Chirgadze, D. Y.; Joudeh, L.; Pellegrini, L.
10.1101/2023.02.18.529066 — biochemistry — Posted on 2023-02-18
1402 Leaf decomposing fungi influence Saccharomyces paradoxus growth across carbon environments
El-Khatib, S.; Lambert, M. G.; Reed, M. N.; Goncalves, M. B.; Boynton, P. J.
10.1101/2023.01.06.523016 — ecology — Posted on 2023-02-18
1405 Long-term, multi-event surprise enhances autobiographical memory
Antony, J. W.; van Dam, J.; Massey, J. R.; Barnett, A. J.; Bennion, K. A.
10.1101/2022.11.27.517985 — neuroscience — Posted on 2023-02-18
1406 Discovery of multi-state gene cluster switches determining the adaptive mitochondrial and metabolic landscape of breast cancer
Menegollo, M.; Bentham, R. B.; Henriques, T.; Ng, S. Q.; Ren, Z.; Esculier, C.; Agarwal, S.; Tong, E.; Ilangovan, S.; Szabadkai, Z.; Suman, M.; Patani, N.; Ghanate, A.; Bryson, K.; Stein, R. C.; Yuneva, M.; Szabadkai, G.
10.1101/2023.02.17.528922 — systems biology — Posted on 2023-02-18
1409 Effects of hepatic mitochondrial pyruvate carrier deficiency on de novo lipogenesis and glycerol-mediated gluconeogenesis in mice
Yiew, N. K. H.; Ferguson, D.; Cho, K.; Deja, S.; Jarasvaraparn, C.; Lutkewitte, A. J.; Mukherjee, S.; Fu, X.; Singer, J. M.; Patti, G. J.; Burgess, S. C.; Finck, B. N.
10.1101/2023.02.17.528992 — physiology — Posted on 2023-02-18
1411 Genome-wide screen reveals Rab12 GTPase as a critical activator of pathogenic LRRK2 kinase
Dhekne, H. S.; Tonelli, F.; Yeshaw, W. M.; Chiang, C. Y.; Limouse, C.; Jaimon, E.; Purlyte, E.; Alessi, D. R.; Pfeffer, S. R.
10.1101/2023.02.17.529028 — biochemistry — Posted on 2023-02-18
1413 Chromatin accessibility associated with aquaculture relevant traits in tilapia
Mehta, T. K.; Man, A.; Ciezarek, A.; Ranson, K. J.; Penman, D.; Di Palma, F.; Haerty, W.
10.1101/2023.02.17.528929 — genomics — Posted on 2023-02-18
1416 A promising QTL QSns.sau-MC-3D.1 likely superior to WAPO1 for wheat spikelet number per spike shows no adverse effects on yield-related traits
Zhou, J.; Li, W.; Yang, Y.; Xie, X.; Liu, J.; Liu, Y.; Tang, H.; Deng, M.; Xu, Q.; Jiang, Q.; Chen, G.; Qi, P.; Jiang, Y.; Chen, G.; He, Y.; Ren, Y.; Tang, L.; Gou, L.; Zheng, Y.; Wei, Y.; Ma, J.
10.1101/2023.02.17.528911 — genetics — Posted on 2023-02-18
1419 Proliferating cell nuclear antigen involves in temperature stress tolerance of Ulva prolifera
He, H.; Yang, J.; He, Y.; Li, Z.; Fu, C.; Zhang, D.; Li, M.; Lu, A.; Dong, J.; Liu, J.; Gu, H.; Shen, S.
10.1101/2023.02.17.529005 — cell biology — Posted on 2023-02-18
1421 Metabolic model predictions enable targeted microbiome manipulation through precision prebiotics
Marinos, G.; Hamerich, I. K.; Debray, R.; Obeng, N.; Petersen, C.; Taubenheim, J.; Zimmermann, J.; Blackburn, D.; Samuel, B. S.; Dierking, K.; Franke, A.; Laudes, M.; Waschina, S.; Schulenburg, H.; Kaleta, C.
10.1101/2023.02.17.528811 — systems biology — Posted on 2023-02-18
1423 Ketogenic diet promotes tumor ferroptosis but induces relative corticosterone deficiency that accelerates cachexia
Ferrer, M.; Mourikis, N.; Davidson, E. E.; Kleeman, S. O.; Zaccaria, M.; Habel, J.; Rubino, R.; Flint, T. R.; Connell, C. M.; Lukey, M.; White, E. P.; Coll, A. P.; Venkitaraman, A. R.; Janowitz, T.
10.1101/2023.02.17.528937 — cancer biology — Posted on 2023-02-18
1427 Integrated Cell Landscape and Dynamics in the Progression of Bone Repair
Shi, J.; Wang, J.; Yin, S.; Lin, S.; Jiang, F.; Zhang, M.; Wu, X.; Shen, L.; Gu, X.; Yang, R.; Yang, J.; Wen, J.; Zhang, W.; Chang, Q.; Jiang, X.
10.1101/2023.02.17.528986 — cell biology — Posted on 2023-02-18
1428 Bacterial responses to complex mixtures of chemical pollutants
Smith, T. P.; Clegg, T.; Ransome, E.; Martin-Lilley, T.; Rosindell, J.; Woodward, G.; Pawar, S.; Bell, T.
10.1101/2023.02.18.529059 — microbiology — Posted on 2023-02-18
1430 Somatodendritic orientation determines tDCS-induced neuromodulation of Purkinje cell activity in awake mice.
Sanchez-Leon, C. A.; Sanchez-Garrido Campos, G.; Fernandez, M.; Sanchez-Lopez, A.; Medina, J. F.; Marquez-Ruiz, J.
10.1101/2023.02.18.529047 — neuroscience — Posted on 2023-02-18
1433 Arousal state transitions occlude sensory-evoked neurovascular coupling in neonatal mice
Gheres, K. W.; Unsal, H. S.; Han, X.; Turner, K. L.; Zhang, Q.; Zhang, N.; Drew, P. J.
10.1101/2023.02.18.529057 — neuroscience — Posted on 2023-02-18
1434 Hebbian priming of human spinal motor learning
Bjoerndal, J. R.; Beck, M. M.; Jespersen, L.; Christiansen, L.; Lundbye-Jensen, J.
10.1101/2023.02.17.528541 — neuroscience — Posted on 2023-02-18
1438 FriendlyClearMap: An optimized toolkit for mouse brain mapping and analysis
Negwer, M.; Bosch, B.; Bormann, M.; Hesen, R.; Lütje, L.; Aarts, L.; Rossing, C.; Nadif Kasri, N.; Schubert, D.
10.1101/2023.02.16.528882 — neuroscience — Posted on 2023-02-18
1439 Differentiation of white matter histopathology using b-tensor encoding and machine learning
Rios-Carrillo, R.; Ramirez-Manzanares, A.; Luna-Munguia, H.; Regalado, M.; Concha, L.
10.1101/2023.02.17.529024 — neuroscience — Posted on 2023-02-18
1440 Astrocytic TIMP-1 regulates production of Anastellin, a novel inhibitor of oligodendrocyte differentiation and FTY720 responses
Sutter, P. A.; Willis, C. M.; Menoret, A.; Nicaise, A. M.; Sacino, A. V.; Sikkema, A. H.; Jellison, E. R.; Win, K. K.; Han, D. K.; Church, W.; Baron, W.; Vella, A. T. J.; Crocker, S. J.
10.1101/2023.02.17.529003 — neuroscience — Posted on 2023-02-18
1444 Biomimetic multi-channel microstimulation of somatosensory cortex conveys high resolution force feedback for bionic hands
Greenspon, C. M.; Valle, G.; Hobbs, T.; Verbaarschot, C.; Callier, T.; Schelchkova, N.; Sobinov, A.; Jordan, P.; Weiss, J. M.; Fitzgerald, E.; Prasad, D.; van Driesche, A.; Lee, R.; Satzer, D.; Gonzalez-Martinez, J.; Warnke, P.; Miller, L. E.; Boninger, M.; Collinger, J.; Gaunt, R.; Hatsopoulos, N.; Downey, J. E.; Bensmaia, S. J.
10.1101/2023.02.18.528972 — neuroscience — Posted on 2023-02-18
1446 ArMo: An Articulated Mesh Approach for Mouse 3D Reconstruction
Bohnslav, J. P.; Osman, M. A. M.; Jaggi, A.; Soares, S.; Weinreb, C.; Datta, S. R.; Harvey, C. D.
10.1101/2023.02.17.526719 — animal behavior and cognition — Posted on 2023-02-18
1454 Defective mechanosensory transduction of the new inner hair cells prevents hearing recover in the damaged cochlea
Li, X.; Ren, M.; Gu, Y.; Zhu, T.; Zhang, Y.; Li, J.; Li, C.; Wang, G.; Song, L.; Bi, Z.; Liu, Z.
10.1101/2023.02.18.529042 — neuroscience — Posted on 2023-02-18
1456 The oncogenic role of Streptococcus gallolyticus subsp. gallolyticus is linked to activation of multiple cancer-related signaling pathways
Pasquereau-Kotula, E.; Nigro, G.; Dingli, F.; Loew, D.; Poullet, P.; Xu, Y.; Kopetz, S.; Davis, J.; Peduto, L.; Robbe-Masselot, C.; Sansonetti, P.; Trieu-Cuot, P.; Dramsi, S.
10.1101/2023.02.17.528913 — microbiology — Posted on 2023-02-18
1458 Single-cell transcriptomics analysis reveals extracellular matrix remodelling in carious human dental pulp
Balic, A.; Perver, D.; Pagella, P.; Rehrauer, H.; Stadlinger, B.; Moor, A. E.; Vogel, V.; Mitsiadis, T.
10.1101/2023.02.15.528696 — cell biology — Posted on 2023-02-18
1461 Oncogenic KrasG12D specific non-covalent inhibitor reprograms tumor microenvironment to prevent and reverse early pre-neoplastic pancreatic lesions and in combination with immunotherapy regresses advanced PDAC in a CD8+ T cells dependent manner
Mahadevan, K. K.; McAndrews, K.; LeBleu, V.; Yang, S.; Lyu, H.; Li, B.; Sockwell, A. M.; Kirtley, M. L.; Morse, S. J.; Moreno Diaz, B. M.; Kim, M. P.; Feng, N.; Lopez, A. M.; Guerrero, P. A.; Sugimoto, H.; Arian, K. A.; Ying, H.; Barekatain, Y.; Kelly, P. J.; Maitra, A.; Heffernan, T. P.; Kalluri, R.
10.1101/2023.02.15.528757 — cancer biology — Posted on 2023-02-18
1462 The Antarctic Seafloor Annotated Imagery Database
Jansen, J.; Shelamoff, V.; Gros, C.; Windsor, T.; Hill, N. A.; Barnes, D. K.; Bowden, D. A.; Gutt, J.; Bax, N.; Downey, R.; Eleaume, M.; Post, A. L.; Griffiths, H. J.; Linse, K.; Piepenburg, D.; Purser, A.; Smith, C. R.; Ziegler, A. F.; Johnson, C. R.
10.1101/2023.02.16.528770 — ecology — Posted on 2023-02-18
1463 Neutralization of SARS-CoV-2 BQ.1.1 and XBB.1.5 by Breakthrough Infection Sera from Previous and Current Waves in China
Wang, X.; Jiang, S.; Jiang, S.; Li, X.; Ai, J.; Lin, K.; Lv, S.; Zhang, S.; Li, M.; He, X.; Li, D.; Li, C.; Zhao, C.; Zhao, X.; Qiao, R.; Cui, Y.; Chen, Y.; Li, J.; Cai, G.; Li, J.; Dai, L.; Hu, Z.; Zhang, W.; Zhang, Y.; Wang, P.
10.1101/2023.02.07.527406 — immunology — Posted on 2023-02-18
1464 Transcriptional heterogeneity in diabetic foot wounds
Sandoval-Schaefer, T.; Phan, Q.; Dash, B.; Prassinos, A.; Duan, K.; Gazes, M. I.; Vyce, S. D.; Hsai, H. C.; Driskell, R.; Horsley, V.
10.1101/2023.02.16.528839 — cell biology — Posted on 2023-02-18
1465 Single-cell transcriptome analysis on the anatomic positional heterogeneity of pig skin
Zou, Q.; Yuan, R.; Zhang, Y.; Wang, Y.; Zheng, T.; Shi, R.; Zhang, M.; Li, Y.; Fei, K.; Feng, R.; Pan, B.; Zhang, X.; Gong, Z.; Zhu, L.; Tang, G.; Li, M.; Li, X.; Jiang, Y.
10.1101/2023.02.17.528908 — cell biology — Posted on 2023-02-18
1470 Single-molecule sizing through nano-cavity confinement
Jacquat, R. P. B.; Krainer, G.; Peter, Q.; Babar, A. N.; Vanderpoorten, O.; Xu, C. K.; Kaminski, C. F.; Keyser, U. F.; Baumberg, J. J.; Knowles, T. P. J.
10.1101/2021.12.13.472369 — biophysics — Posted on 2023-02-18
1471 Vimentin impacts centrosome function and microtubule acetylation
Saldanha, R.; Tri Ho Thanh, M.; Krishnan, N.; Hehnly, H.; Patteson, A. E.
10.1101/2023.02.17.528977 — cell biology — Posted on 2023-02-18
1473 Improving gene regulatory network inference and assessment: The importance of using network structure
Escorcia-Rodriguez, J. M.; Gaytan-Nunez, E.; Hernandez-Benitez, E. M.; Zorro-Aranda, A.; Tello-Palencia, M. A.; Freyre-Gonzalez, J. A.
10.1101/2023.01.12.523840 — systems biology — Posted on 2023-02-18
1477 An international scholastic network to generate LexA enhancer-trap lines for Drosophila
Kim, E. S.; Rajan, A.; Chang, K.; Gulick, C.; English, E.; Govindarajan, S.; Rodriguez, B. R.; Bloomfield, O.; Nakada, S.; Beard, C.; O'Connor, S.; Mastroianni, S.; Downey, E.; Feigenbaum, M.; Tolentino, C.; Pace, A.; Khan, M.; Moon, S.; DiPrima, J.; Syed, A.; Lin, F.; Abukhadra, Y.; Bacon, I.; Beckerle, J.; Cho, S.; Esi Donkor, N.; Garberg, L.; Harrington, A.; Hoang, M.; Lawani, N.; Noori, A.; Park, E.; Parsons, E.; Oravitan, P.; Chen, M.; Molina, C.; Richmond, C.; Reddi, A.; Huang, J.; Shugrue, C.; Coviello, R.; Unver, S.; Indelicarto, M.; Islamovic, E.; McIlroy, R.; Yang, A.; Hamad, M.; Gri
10.1101/2022.11.24.517565 — genetics — Posted on 2023-02-18
1478 Metformin impairs trophoblast metabolism and differentiation in dose dependent manner
Nashif, S. K.; Mahr, R. M.; Jena, S.; Jo, S.; Nelson, A. B.; Sadowski, D.; Crawford, P. A.; Puchalska, P.; Alejandro, E. U.; Gearhart, M. D.; Wernimont, S. A.
10.1101/2023.02.14.528531 — cell biology — Posted on 2023-02-18
1484 Common roles for serotonin in rats and humans for computations underlying flexible decision-making
Luo, Q.; Kanen, J. W.; Bari, A.; Skandali, N.; Langley, C.; Knudsen, G. M.; Alsio, J.; Phillips, B. U.; Sahakian, B. J.; Cardinal, R. N.; Robbins, T. W.
10.1101/2023.02.15.527569 — neuroscience — Posted on 2023-02-17
1485 The Essential Role of O-GlcNAcylation in Hepatic Differentiation
Robarts, D. R.; Kotulkar, M.; Paine-Cabrera, D.; Venneman, K. K.; Hanover, J. A.; Zachara, N. E.; Slawson, C.; Apte, U.
10.1101/2023.02.16.528884 — pathology — Posted on 2023-02-17
1486 Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A
Harjes, S.; Kurup, H. M.; Rieffer, A. E.; Bayarjagal, M.; Filitcheva, J.; Su, Y.; Hale, T. K.; Filichev, V. V.; Harjes, E.; Harris, R. S.; Jameson, G. B.
10.1101/2023.02.17.528918 — cancer biology — Posted on 2023-02-17
1487 Discovery of novel microRNA regulators of ribosome biogenesis
Bryant, C. J.; McCool, M. A.; Rosado-Gonzalez, G. T.; Abriola, L.; Surovtseva, Y. V.; Baserga, S. J.
10.1101/2023.02.17.526327 — biochemistry — Posted on 2023-02-17
1488 Resolving the haplotypes of arbuscular mycorrhizal fungi highlights the role of two nuclear populations in host interactions
Sperschneider, J.; Yildirir, G.; Rizzi, Y.; Malar C, M.; Ariane Mayrand Nicol, A.; Sorwar, E.; Chen, E. C.; Iwasaki, W.; Brauer, E. K.; Bosnich, W.; Gutjahr, C.; Corradi, N.
10.1101/2023.01.15.524138 — genomics — Posted on 2023-02-17
1493 Starvation sensing by mycobacterial RelA/SpoT homologue through constitutive surveillance of translation
Li, Y.; Majumdar, S.; Treen, R.; Sharma, M. R.; Corro, J.; Gamper, H.; Manjari, S. R.; Prusa, J.; Banavali, N. K.; Stallings, C. L.; Hou, Y.-M.; Agrawal, R. K.; Ojha, A. K.
10.1101/2022.12.29.522164 — molecular biology — Posted on 2023-02-17
1495 Disease-specific loss of microbial cross-feeding interactions in the human gut
Rossetto Marcelino, V.; Welsh, C.; Diener, C.; Gulliver, E. L.; Rutten, E. L.; Young, R. B.; Giles, E. M.; Gibbons, S. M.; Greening, C.; Forster, S. C.
10.1101/2023.02.17.528570 — microbiology — Posted on 2023-02-17
1500 Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability
Duveau, F. M.; Cordier, C.; Chiron, L.; Le Bec, M.; Pouzet, S.; Seguin, J.; Llamosi, A.; Sorre, B.; Di Meglio, J.-M.; Hersen, P.
10.1101/2023.02.17.528926 — systems biology — Posted on 2023-02-17
1501 Pathology of naturally acquired high pathogenicity avian influenza virus H5N1 infection in seabirds
Lean, F. Z.; Falchieri, M.; Furman, N.; Tyler, G.; Robinson, C.; Holmes, P.; Reid, S. M.; Banyard, A. C.; Brown, I. H.; Man, C.; Nunez, A.
10.1101/2023.02.17.528990 — pathology — Posted on 2023-02-17
1505 Predicting transcription factor activity using prior biological information
Estabrook, J.; Yashar, W. M.; Holly, H. D.; Somers, J.; Nikolova, O.; Babur, O.; Braun, T. P.; Demir, E.
10.1101/2022.12.16.520295 — bioinformatics — Posted on 2023-02-17
1508 Whole mouse body histology using standard IgG antibodies
Mai, H.; Luo, J.; Hoeher, L.; Maskari, R. A.; Horvath, I.; Paetzold, J.; Todorov, M.; Hellal, F.; Erturk, A.
10.1101/2023.02.17.528921 — biochemistry — Posted on 2023-02-17
1509 Pangolin genomes offer key insights and resources for the world's most trafficked wild mammals
Heighton, S. P.; Allio, R.; Murienne, J.; Salmona, J.; Meng, H.; Scornavacca, C.; Bastos, A. D. S.; Njiokou, F.; Pietersen, D. W.; Tilak, M.-K.; Luo, S.-J.; Delsuc, F.; Gaubert, P.
10.1101/2023.02.16.528682 — genomics — Posted on 2023-02-17
1511 Diversity in the internal functional feeding elements of sympatric morphs of Arctic charr (Salvelinus alpinus)
Jonsdottir, G. O.; von Elm, L.-M.; Ingimarsson, F.; Tersigni, S.; Snorrason, S. S.; Palsson, A.; Steele, S. E.
10.1101/2023.02.17.528955 — evolutionary biology — Posted on 2023-02-17
1513 Evolution of horn length and lifting strength in the Japanese rhinoceros beetle Trypoxylus dichotomus
Weber, J. N.; Kojima, W.; Boisseau, R.; Niimi, T.; Morita, S.; Shigenobu, S.; Gotoh, H.; Araya, K.; Lin, C.-P.; Thomas-Bulle, C.; Allen, C. E.; Tong, W.; Lavine, L. C.; Swanson, B. O.; Emlen, D. J.
10.1101/2023.02.16.528888 — evolutionary biology — Posted on 2023-02-17
1516 Within-species variation in the gut microbiome of fish is driven by the interaction of light intensity and genetic background
Evangelista, C.; Kamenova, S.; Diaz Pauli, B.; Sandkjenn, J.; Vollestad, A.; Edeline, E.; Trosvik, P.; de Muinck, E.
10.1101/2023.02.17.528956 — ecology — Posted on 2023-02-17
1518 A cleaved METTL3 potentiates the METTL3-WTAP interaction and breast cancer progression
Zhang, J.; Yan, C.; Xiong, J.; Zhou, Z.; Li, Q.; Gao, C.; Zhang, M.; Yu, L.; Li, J.; Hu, M.-M.; Zhang, C.-S.; Cai, C.; Zhang, H.
10.1101/2023.02.17.528944 — cell biology — Posted on 2023-02-17
1520 FKBP35 secures ribosome homeostasis in Plasmodium falciparum
Thommen, B. T.; Dziekan, J. M.; Achcar, F.; Tjia, S.; Passecker, A.; Buczak, K.; Gumpp, C.; Schmidt, A.; Rottmann, M.; Gruering, C.; Marti, M.; Bozdech, Z.; Brancucci, N. M. B.
10.1101/2022.12.09.519720 — molecular biology — Posted on 2023-02-17
1522 Fibroblastic cells are a site of mouse cytomegalovirus in vivo lytic replication and latent persistence oppositely regulated by Stat1
Sitnik, K. M.; Krstanovic, F.; Goedecke, N.; Rand, U.; Kubsch, T.; Maas, H.; Kim, Y.; Brizic, I.; Cicin-Sain, L.
10.1101/2022.06.29.498076 — microbiology — Posted on 2023-02-17
1524 Translatome analysis reveals microglia and astrocytes to be distinct regulators of inflammation in the hyperacute and acute phases after stroke
Hernandez, V. G.; Lechtenberg, K. J.; Peterson, T. C.; Zhu, L.; Lucas, T. A.; Owah, J. O.; Dorsey, A. I.; Gentles, A. J.; Buckwalter, M. S.
10.1101/2023.02.14.520351 — neuroscience — Posted on 2023-02-17
1525 Early Path Dominance as a Principle for Neurodevelopment
Razban, R. M.; Pachter, J. A.; Dill, K. A.; Mujica-Parodi, L. R.
10.1101/2022.07.14.500044 — neuroscience — Posted on 2023-02-17
1529 Template-Directed RIG-I Agonist Assembly for Targeted Cancer Immunotherapy
Ghosh, S. K.; Robertson, N.; Crosier, E.; Dudley, M.; Liu, Q. P.; Medarova, Z.
10.1101/2022.12.08.519592 — bioengineering — Posted on 2023-02-17
1533 Amino acid substitutions in norovirus VP1 dictate cell tropism via an attachment process dependent on membrane mobility.
Mills, J. T.; Minogue, S. C.; Snowden, J. S.; Carnahan, K. E.; Rowlands, D. J.; Stonehouse, N. J.; Wobus, C. E.; Herod, M. R.
10.1101/2023.02.17.528071 — microbiology — Posted on 2023-02-17
1534 New RoxS sRNA targets identified in B. subtilis by pulsed SILAC
Allouche, D.; Kostova, G.; Hamon, M.; Marchand, C. H.; Caron, M.; Belhocine, S.; Christol, N.; Charteau, V.; Condon, C.; DURAND, S.
10.1101/2023.02.17.528916 — microbiology — Posted on 2023-02-17
1537 Broad sensitivity of Candida auris strains to quinolones and mechanisms of resistance
Lohse, M. B.; Laurie, M. T.; Levan, S.; Ziv, N.; Ennis, C. L.; Nobile, C. J.; DeRisi, J. L.; Johnson, A. D.
10.1101/2023.02.16.528905 — microbiology — Posted on 2023-02-17
1538 Hepatitis delta virus RNA decline post inoculation in human NTCP transgenic mice is biphasic
Maya, S.; Hershkovich, L.; Cardozo-Ojeda, E. F.; Shirvani-Dastgerdi, E.; Srinivas, J.; Shektman, L.; Uprichard, S. L.; Berneshawi, A. R.; Cafiero, T. R.; Dahari, H.; Ploss, A.
10.1101/2023.02.17.528964 — microbiology — Posted on 2023-02-17
1548 Centrosome formation in the bovine early embryo.
Uzbekov, R.; Singina, G.; Shedova, E.; Banliat, C.; Avidor-Reiss, T.; Uzbekova, S.
10.1101/2022.11.29.517493 — cell biology — Posted on 2023-02-17
1551 A dynamic occupancy model for interacting species with two spatial scales
Kleiven, E. F.; Barraquand, F.; Gimenez, O.; Henden, J.-A.; Ims, R. A.; Soininen, E. M.; Yoccoz, N. G.
10.1101/2020.12.16.423067 — ecology — Posted on 2023-02-17
1554 Ticagrelor combined with aspirin displays the signature of regulating the gut microbiome in consistence with improving the immuno-inflammatory response in atherosclerosis
Bai, Z.; Zhang, Q.; Liu, Y.; Zhao, Y.; Yan, R.; Yang, L.; Ma, H.; Ren, Y.; Wang, T.; Li, Y.; Liu, Y.; Jiang, X.; Wang, R.; Jia, S.; Zhang, X.; Wang, H.
10.1101/2022.06.22.497138 — immunology — Posted on 2023-02-17
1556 Generation of human cerebral organoids with a structured outer subventricular zone
Walsh, R.; Giacomelli, E.; Ciceri, G.; Rittenhouse, C.; Galimberti, M.; Wu, Y.; Muller, J.; Vezzoli, E.; Jungverdorben, J.; Zhou, T.; Barker, R. A.; Cattaneo, E.; Studer, L.; Baggiolini, A.
10.1101/2023.02.17.528906 — developmental biology — Posted on 2023-02-17
1557 A cell surface code mediates tissue-intrinsic defense against aberrant cells in epithelia
Fischer, F.; Ernst, L.; Frey, A.; Holstein, K.; Prasad, D.; Weichselberger, V.; Balaji, R.; Classen, A.-K.
10.1101/2023.02.16.528665 — cell biology — Posted on 2023-02-17
1559 Pumping Iron: A Multi-omics Analysis of Two Extremophilic Algae Reveals Mechanisms of Iron Economy
Davidi, L.; Gallaher, S. D.; Ben-David, E.; Purvine, S. O.; Fillmore, T. L.; Nicora, C. D.; Craig, R. J.; Schmollinger, S.; Roje, S.; Blaby-Haas, C. E.; Auber, R. P.; Wisecaver, J.; Merchant, S. S.
10.1101/2023.02.09.527888 — systems biology — Posted on 2023-02-17
1560 Complex aneuploidy triggers autophagy and p53-mediated apoptosis and impairs the second lineage segregation in human preimplantation embryos
Regin, M.; Lei, Y.; De Deckersberg, E. C.; Guns, Y.; Verdyck, P.; Verheyen, G.; Van de Velde, H.; Sermon, K.; Spits, C.
10.1101/2022.08.31.506009 — developmental biology — Posted on 2023-02-17
1564 Divergent selection in Mediterranean pine stands on localspatial scales
Budde, K. B.; Rellstab, C.; Heuertz, M.; Gugerli, F.; Verdu, M.; Pausas, J. G.; Gonzalez-Martinez, S. C.
10.1101/2023.02.16.528264 — plant biology — Posted on 2023-02-17
1565 Unlocking the multiphasic nature of intracellular calcium signatures triggered by fungal signals in Lotus japonicus roots
Binci, F.; Offer, E.; Crosino, A.; Sciascia, I.; Kleine-Vehn, J.; Genre, A.; Giovannetti, M.; Navazio, L.
10.1101/2022.04.13.487819 — plant biology — Posted on 2023-02-17
1568 The role of B cells in immune cell activation in polycystic ovary syndrome
Ascani, A.; Torstensson, S.; Risal, S.; Lu, H.; Eriksson, G.; Li, C.; Teshl, S.; Menezes, J.; Sandor, K.; Ohlsson, C.; Svensson, C.; Karlsson, M.; Stradner, M. H.; Obermayer-Pietsch, B.; Stener-Victorin, E.
10.1101/2023.01.26.525671 — immunology — Posted on 2023-02-17
1569 Stimulus novelty uncovers coding diversity in visual cortical circuits
Garrett, M.; Groblewski, P.; Piet, A.; Ollerenshaw, D.; Najafi, F.; Yavorska, I.; Amster, A.; Bennett, C.; Buice, M.; Caldejon, S.; Casal, L.; D'Orazi, F.; Daniel, S.; de Vries, S. E.; Kapner, D.; Kiggins, J.; Lecoq, J.; Ledochowitsch, P.; Manavi, S.; Mei, N.; Morrison, C. B.; Naylor, S.; Orlova, N.; Perkins, J.; Ponvert, N.; Roll, C.; Seid, S.; Williams, D.; Williford, A.; Ahmed, R.; Amine, D.; Billeh, Y.; Bowman, C.; Cain, N.; Cho, A.; Dawe, T.; Departee, M.; Desoto, M.; Feng, D.; Gale, S.; Gelfand, E.; Gradis, N.; Grasso, C.; Hancock, N.; Hu, B.; Hytnen, R.; Jia, X.; Johnson, T.; Kato, I.;
10.1101/2023.02.14.528085 — neuroscience — Posted on 2023-02-17
1570 Assessment of the acute effects of 2C-B vs psilocybin on subjective experience, mood and cognition
Mallaroni, P.; Mason, N. L.; Reckweg, J. T.; Paci, R.; Ritscher, S.; Toennes, S.; Theunissen, E.; Kuypers, K.; Ramaekers, J. G.
10.1101/2023.02.16.528808 — pharmacology and toxicology — Posted on 2023-02-17
1574 DNA 5-methylcytosine detection and methylation phasing using PacBio circular consensus sequencing
Ni, P.; Zhong, Z.; Xu, J.; Huang, N.; Zhang, J.; Nie, F.; Zhao, H.; Zou, Y.; Huang, Y.; Li, J.; Xiao, C.-L.; Luo, F.; Wang, J.
10.1101/2022.02.26.482074 — bioinformatics — Posted on 2023-02-16
1576 The EspN transcription factor is an infection-dependent regulator of the ESX-1 system in M. marinum
Nicholson, K. R.; Cronin, R. M.; Menon, A. R.; Jennisch, M. K.; Tobin, D. M.; Champion, P. A.
10.1101/2023.02.15.528779 — microbiology — Posted on 2023-02-16
1579 Fiberbots: Robotic fibers for high-precision minimally invasive surgery
Abdelaziz, M. E. M. K.; Zhao, J.; Rosa, B. M. G.; Lee, H.-T.; Simon, D.; Vyas, K.; Li, B.; Koguna, H. J. A.; Li, Y.; Demircali, A. A.; Uvet, H.; Gencoglan, G.; Akcay, A.; Elriedy, M.; Kinross, J. M.; Dasgupta, R.; Takats, Z.; Yeatman, E.; Yang, G.-Z.; Temelkuran, B.
10.1101/2023.02.16.528823 — bioengineering — Posted on 2023-02-16
1584 Signaling from the C. elegans Hypodermis Non-autonomously Facilitates Short-term Associative Memory
Zhou, S.; Zhang, Y.-P.; Kaletsky, R.; Toraason, E.; Zhang, W.; Dong, M.-Q.; Murphy, C. T.
10.1101/2023.02.16.528821 — genetics — Posted on 2023-02-16
1589 Recognition of commensal bacterial peptidoglycans defines Drosophila gut homeostasis and lifespan
Onuma, T.; Toshitaka, Y.; Kosakamoto, H.; Kadoguchi, H.; Kuraishi, T.; Murakami, T.; Mori, H.; Miura, M.; Obata, F.
10.1101/2023.02.16.528767 — immunology — Posted on 2023-02-16
1590 The tetrapeptide sequence of IL-1β regulates its recruitment and activation by inflammatory caspases
Exconde, P. M.; Hernandez-Chavez, C.; Bray, M. B.; Lopez, J. L.; Srivastava, T.; Egan, M. S.; Zhang, J.; Shin, S.; Discher, B. M.; Taabazuing, C. Y.
10.1101/2023.02.16.528859 — immunology — Posted on 2023-02-16
1591 Exposure to an enriched environment improves colonic epithelial barrier integrity and attenuates mouse experimental colitis by modulating a Myc-driven gene regulatory network
Villa-Senor-Toledo, T.; Valle-Garcia, D.; Pop, R. T.; Osio-Becerro, V.; Meza-Sosa, K. F.; Serrano, C.; Diaz de Leon-Guerrero, S.; Hernandez-Pando, R.; Nava, P.; Kuijjer, M. L.; Perez-Martinez, L.; Pedraza-alva, G.
10.1101/2023.02.16.528051 — immunology — Posted on 2023-02-16
1592 An Optrode Array for Spatiotemporally Precise Large-Scale Optogenetic Stimulation of Deep Cortical Layers in Non-human Primates
Clark, A. M.; Ingold, A.; Reiche, C. F.; Cundy, D.; Balsor, J. L.; Federer, F.; McAlinden, N.; Cheng, Y.; Rolston, J. D.; Rieth, L.; Dawson, M. D.; Mathieson, K.; Blair, S.; Angelucci, A.
10.1101/2022.02.09.479779 — neuroscience — Posted on 2023-02-16
1598 Molecular landscape and functional characterization of centrosome amplification in ovarian cancer
Sauer, C. M.; Hall, J. A.; Couturier, D.-L.; Bradley, T.; Piskorz, A. M.; Griffiths, J.; Sawle, A.; Eldridge, M. D.; Smith, P.; Hosking, K.; Reinius, M. A.; Morrill Gavarro, L.; Mes-Masson, A.-M.; Ennis, D.; Millan, D.; Hoyle, A.; McNeish, I. A.; Jimenez-Linan, M.; Correia Martins, F.; Tischer, J.; Vias, M.; Brenton, J. D.
10.1101/2022.09.13.507750 — cancer biology — Posted on 2023-02-16
1599 Oncogenic KrasG12D specific non-covalent inhibitor reprograms tumor microenvironment to prevent and reverse early pre-neoplastic pancreatic lesions and in combination with immunotherapy regresses advanced PDAC in a CD8+ T cells dependent manner
Mahadevan, K. K.; McAndrews, K.; LeBleu, V.; Yang, S.; Lyu, H.; Li, B.; Sockwell, A. M.; Kirtley, M. L.; Morse, S. J.; Moreno Diaz, B. M.; Kim, M. P.; Feng, N.; Lopez, A. M.; Guerrero, P. A.; Sugimoto, H.; Arian, K. A.; Ying, H.; Barekatain, Y.; Kelly, P. J.; MAITRA, A.; Heffernan, T. P.; Kalluri, R.
10.1101/2023.02.15.528757 — cancer biology — Posted on 2023-02-16
1603 μCas, a novel class of miniature type-V Cas12f nucleases with diverse PAM
Sharrar, A.; Arake de Tacca, L.; Collingwood, T.; Meacham, Z.; Rabuka, D.; Staples-Ager, J.; Schelle, M.
10.1101/2023.02.03.527072 — biochemistry — Posted on 2023-02-16
1604 Massively parallel characterization of psychiatric disorder-associated and cell-type-specific regulatory elements in the developing human cortex
Deng, C.; Whalen, S.; Steyert, M.; Ziffra, R.; Przytycki, P. F.; Inoue, F.; Pereira, D. A.; Capauto, D.; Norton, S.; Vaccarino, F. M.; Pollen, A. A.; Nowakowski, T. J.; Ahituv, N.; Pollard, K. S.
10.1101/2023.02.15.528663 — genomics — Posted on 2023-02-16
1607 Functional significance of PUF partnerships in C. elegans germline stem cells
Ferdous, A. S.; Costa Dos Santos, S. J.; Kanzler, C. R.; Shin, H.; Carrick, B. H.; Crittenden, S. L.; Wickens, M.; Kimble, J.
10.1101/2023.02.15.528708 — developmental biology — Posted on 2023-02-16
1608 Fibroblastic cells are a site of mouse cytomegalovirus in vivo lytic replication and latent persistence oppositely regulated by Stat1
Sitnik, K. M.; Krstanovic, F.; Goedecke, N.; Rand, U.; Kubsch, T.; Maas, H.; Kim, Y.; Brizic, I.; Cicin-Sain, L.
10.1101/2022.06.29.498076 — microbiology — Posted on 2023-02-16
1609 Gut microbes and their genes are associated with cognitive performance and brain structure in children
Bonham, K. S.; Bottino, G. F.; McCann, S. H.; Beauchemin, J.; Weisse, E.; Barry, F.; Cano-Lorente, R.; RESONANCE Consortium, ; Huttenhower, C.; Bruchhage, M. M. K.; D'Sa, V.; Deoni, S.; Klepac-Ceraj, V.
10.1101/2020.02.13.944181 — microbiology — Posted on 2023-02-16
1611 Multimodal measures of spontaneous brain activity reveals both common and divergent patterns of cortical functional organization
Vafaii, H.; Mandino, F.; Desrosiers-Gregoire, G.; O'Connor, D.; Shen, X.; Ge, X.; Herman, P.; Hyder, F.; Papademetris, X.; Chakravarty, M.; Crair, M.; Constable, R. T.; Lake, E. M.; Pessoa, L.
10.1101/2022.12.13.520297 — neuroscience — Posted on 2023-02-16
1612 Electrical synapse formation is differentially regulated by distinct isoforms of a postsynaptic scaffold
Michel, J. C.; Grivette, M. M. B.; Harshfield, A. T.; Huynh, L.; Komons, A. P.; Loomis, B.; McKinnis, K.; Miller, B. T.; Huang, T. W.; Lauf, S.; Michel, E. S.; Michel, M. E.; Marsh, A. J.; Kaye, L. E.; Lasseigne, A. M.; Lukowicz-Bedford, R. M.; Farnsworth, D. R.; Martin, E. A.; Miller, A. C.
10.1101/2022.06.27.497867 — neuroscience — Posted on 2023-02-16
1613 Geometric constraints on human brain function
Pang, J. C.; Aquino, K. M.; Oldehinkel, M.; Robinson, P. A.; Fulcher, B. D.; Breakspear, M.; Fornito, A.
10.1101/2022.10.04.510897 — neuroscience — Posted on 2023-02-16
1615 Chronic Alcohol Drinking Drives Sex-Specific Differences in Affective Behavior and Medial Prefrontal Cortex Activity in CRF1:Cre:Tdtomato Transgenic Rats
Quadir, S. G.; Arleth, G. M.; Cone, M. G.; High, M. W.; Ramage, M. C.; Effinger, D. P.; Echeveste Sanchez, M.; Herman, M. A.
10.1101/2022.11.14.516444 — neuroscience — Posted on 2023-02-16
1617 Exploring the onset and progression of prostate cancer through a multicellular agent-based model
Passier, M.; van Genderen, M.; Zaalberg, A.; Kneppers, J.; Bekers, E.; Bergman, A. M.; Zwart, W.; Eduati, F.
10.1101/2023.02.16.528831 — systems biology — Posted on 2023-02-16
1618 Hemi Manganese Exporters 1 and 2 enable manganese transport at the plasma membrane in cyanobacteria
Reis, M.; Brandenburg, F.; Knopp, M.; Flachbart, S.; Braeutigam, A.; Metzger, S.; Gould, S. B.; Eisenhut, M.
10.1101/2023.02.16.528846 — plant biology — Posted on 2023-02-16
1619 Breast Density Analysis Using Digital Breast Tomosynthesis
Heine, J.; Fowler, E. E. E.; Weinfurtner, R. J.; Tworoger, S.; Hume, E.
10.1101/2023.02.10.527911 — biophysics — Posted on 2023-02-16
1621 Lineage segregation in human pre-implantation embryos is specified by YAP1 and TEAD1
Regin, M.; Essahib, W.; Demtschenko, A.; Dewandre, D.; David, L.; Gerri, C.; Niakan, K.; Verheyen, G.; Tournaye, H.; Sterckx, J.; Sermon, K.; Van de Velde, H.
10.1101/2022.09.29.509946 — developmental biology — Posted on 2023-02-16
1622 A bacterial ribosome hibernation factor with evolutionary connections to eukaryotic protein synthesis
Helena-Bueno, K.; Ekemezie, C. L.; Brown, C. R.; Basle, A.; Blaza, J. N.; Hill, C. H.; Melnikov, S. V.
10.1101/2022.11.24.517861 — molecular biology — Posted on 2023-02-16
1623 Allergic Asthma Responses Are Dependent on Macrophage Ontogeny
Tighe, R. M.; Birukova, A.; Malakhau, Y.; Kobayashi, Y.; Vose, A. T.; Chandramohan, V.; Cyphert-Daly, J. M.; Cumming, R. I.; Kirshner, H. F.; Tata, P. R.; Ingram, J. L.; Gunn, M. D.; Que, L. G.; Yu, Y.-R. A.
10.1101/2023.02.16.528861 — immunology — Posted on 2023-02-16
1626 A peptide-centric quantitative proteomics dataset for the phenotypic assessment of Alzheimer's disease
Merrihew, G. E.; Park, J.; Plubell, D.; Searle, B. C.; Keene, C. D.; Larson, E. B.; Bateman, R.; Perrin, R. J.; Chhatwal, J. P.; Farlow, M. R.; McLean, C. A.; Ghetti, B.; Newell, K. L.; Frosh, M. P.; Montine, T.; MacCoss, M. J.
10.1101/2022.11.04.515203 — neuroscience — Posted on 2023-02-16
1627 An ancient thyrostimulin-like neuroendocrine pathway regulates growth in Caenorhabditis elegans
Kenis, S.; Istiban, M. N.; Van Damme, S.; Vandewyer, E.; Watteyne, J.; Schoofs, L.; Beets, I.
10.1101/2023.02.16.528858 — neuroscience — Posted on 2023-02-16
1628 Somatotopic organization among parallel sensory pathways that promote a grooming sequence in Drosophila
Eichler, K.; Hampel, S.; Alejandro, A.; Calle, S.; Santana, A.; Kmecova, L.; Blagburn, J. M.; Hoopfer, E. D.; Seeds, A. M.
10.1101/2023.02.11.528119 — neuroscience — Posted on 2023-02-16
1629 Firing rate adaptation affords place cell theta sweeps, phase precession and procession
Chu, T.; Ji, Z.; Zuo, J.; Mi, Y.; Zhang, W.-H.; Huang, T.; Bush, D.; Burgess, N.; Wu, S.
10.1101/2022.11.14.516400 — neuroscience — Posted on 2023-02-16
1631 Proteomic analyses of the Arabidopsis cap-binding complex define core set and TOR-dependent protein components
Matthes, A.; Ouibrahim, L.; Lecampion, C.; Caranta, C.; Davanture, M.; Lebrun, R.; Coute, Y.; Baudet, M.; Meyer, C.; Robaglia, C.
10.1101/2023.02.16.528822 — plant biology — Posted on 2023-02-16
1634 Rational Prediction of PROTAC-compatible Protein-Protein Interfaces by Molecular Docking
Pereira, G.; Garcia, B. J.; Pellarin, R.; Launay, G.; Wu, S.; Martin, J.; de Souza, P. C. T.
10.1101/2023.02.16.528819 — bioinformatics — Posted on 2023-02-16
1638 Genetic manipulation of betta fish
Palmiotti, A.; Lichak, M. R.; Shih, P.-Y.; Bendesky, A.
10.1101/2023.02.16.528733 — genetics — Posted on 2023-02-16
1639 Inhibition of haao-1 enhances oxidative stress response by activating hormetic redox signaling in C. elegans.
Castro-Portuguez, R.; Raymond, K. M.; Thullen, E.; Hendrickson, A. M.; Freitas, S.; Hull, B.; Meyers, J. B.; Thorns, N.; Gardea, E. A.; Dang, H.; Espejo, L. S.; Sutphin, G. L.
10.1101/2023.02.16.528568 — molecular biology — Posted on 2023-02-16
1641 Redox Regulation of m6A Methyltransferase METTL3 in Human β-cells Controls the Innate Immune Response in Type 1 Diabetes
De Jesus, D. F.; Zhang, Z.; Brown, N. K.; Li, X.; Gaffrey, M. J.; Kahraman, S.; Wei, J.; Hu, J.; Basile, G.; Xiao, L.; Rana, T. M.; Mathews, C. E.; Powers, A. C.; Atkinson, M. A.; Eizirik, D. L.; Dhe-Paganon, S.; Parent, A. V.; Qian, W.-J.; He, C.; Kulkarni, R. N.
10.1101/2023.02.16.528701 — molecular biology — Posted on 2023-02-16
1644 Spatially localized expression of glutamate decarboxylase gadB in Escherichia coli O157:H7 microcolonies in hydrogel matrix
Saint Martin, C.; Caccia, N.; Darsonval, M.; Gregoire, M.; Combeau, A.; Jubelin, G.; Dubois-Brissonnet, F.; Leroy, S.; Briandet, R.; Desvaux, M.
10.1101/2023.02.16.528592 — microbiology — Posted on 2023-02-16
1647 The pseudokinase Trib1 regulates the transition of exhausted T cells to a KLR+ CD8+ effector state and its deletion improves checkpoint blockade
McClory, S. E.; Bardhan, O.; Rome, K. S.; Giles, J. R.; Baxter, A. E.; Xu, L.; Gimotty, P. A.; Faryabi, R. B.; Wherry, E. J.; Pear, W. S.; Jordan, M. S.
10.1101/2023.02.16.528833 — immunology — Posted on 2023-02-16
1648 Mapping Sleep's Oscillatory Events as a Biomarker of Alzheimer's Disease
Pulver, R. L.; Kronberg, E.; Medenblik, L. M.; Kheyfets, V. O.; Ramos, A. R.; Holtzman, D. M.; Morris, J. C.; Toedebusch, C. D.; Sillau, S. H.; Bettcher, B. M.; Lucey, B. P.; McConnell, B. V.
10.1101/2023.02.15.528725 — neuroscience — Posted on 2023-02-16
1650 Endothelial Cells are Heterogeneous in Different Brain Regions and are Dramatically Altered in Alzheimer's Disease
Bryant, A. G.; Li, Z.; Jayakumar, R.; Serrano-Pozo, A.; Woost, B.; Hu, M.; Woodbury, M. E.; Wachter, A.; Lin, G.; Kwon, T.; Talanian, R. V.; Biber, K.; Karran, E. H.; Hyman, B. T.; Das, S.; Bennett, R. E.
10.1101/2023.02.16.528825 — neuroscience — Posted on 2023-02-16
1653 Assessment of the acute effects of 2C-B vs psilocybin on subjective experience, mood and cognition
Mallaroni, P.; Mason, N. L.; Reckweg, J. T.; Paci, R.; Toennes, S.; Theunissen, E.; Kuypers, K.; Ramaekers, J. G.
10.1101/2023.02.16.528808 — pharmacology and toxicology — Posted on 2023-02-16
1654 BCM PDX Portal: An Intuitive Web-based Tool for Patient-Derived Xenograft Collection Management, as well as Visual Integration of Clinical and Omics Data
Dowst, H.; McOwiti, A.; Zheng, F.; Rajaram Srinivasan, R.; Hernandez-Herrera, A.; Rainusso, N.; Brubaker, L.; Yao, Q. C.; Redell, M.; Stevens, A.; Lerner, S.; Woodfield, S.; Espinoza, A. F.; Landua, J. D.; Hilsenbeck, S. G.; Dobrolecki, L. E.; Lewis, M. T.
10.1101/2023.02.15.528735 — cancer biology — Posted on 2023-02-16
1657 The histone chaperone activity of SPT2 controls chromatin structure and function in Metazoa
Saredi, G.; Carelli, F. N.; Furlan, G.; Rolland, S.; Piquet, S.; Appert, A.; Sanchez-Pulido, L.; Price, J. L.; Alcon, P.; Lampersberger, L.; Declais, A.-C.; Ramakrishna, N. B.; Toth, R.; Ponting, C. P.; Polo, S. E.; Miska, E. A.; Ahringer, J.; Gartner, A.; Rouse, J.
10.1101/2023.02.16.528451 — molecular biology — Posted on 2023-02-16
1658 An integrated transcriptomics-functional genomics approach reveals a small RNA that modulates Bacteroides thetaiotaomicron sensitivity to tetracyclines
Ryan, D.; Bornet, E.; Prezza, G.; Alampalli, S. V.; de Carvalho, T. F.; Felchle, H.; Ebbecke, T.; Hayward, R.; Deutschbauer, A.; Barquist, L.; Westermann, A. J.
10.1101/2023.02.16.528795 — molecular biology — Posted on 2023-02-16
1660 Whole-brain structural connectome asymmetry in autism
Yoo, S.; Jang, Y.; Hong, S.-J.; Park, H.; Valk, S. L.; Bernhardt, B. C.; Park, B.-y.
10.1101/2023.02.15.528746 — neuroscience — Posted on 2023-02-16
1661 Local-scale divergent selection in a Mediterranean pine
Budde, K. B.; Rellstab, C.; Heuertz, M.; Gugerli, F.; Verdu, M.; Pausas, J. G.; Gonzalez-Martinez, S. C.
10.1101/2023.02.16.528264 — plant biology — Posted on 2023-02-16
1662 Development of a human glioblastoma model using humanized DRAG mice for immunotherapy
Srivastava, R.; Labani-Motlagh, A.; Chen, A.; Yang, F.; Ansari, D.; Patel, S.; Ji, H.; Trasti, S.; Dodda, M.; Patel, Y.; Zou, H.; Hu, B.; Yi, G.
10.1101/2023.02.15.528743 — cancer biology — Posted on 2023-02-16
1665 A robust method for the rapid generation of nanobodies.
He, L.; Tao, Z.; Wang, H.; Zhao, X.; Zhang, J.; jiang, G.; Yu, B.; Chen, Y.; Zhu, M.; Long, J.; Yin, L.; Zhang, X.; Liu, M.
10.1101/2023.02.15.528753 — biochemistry — Posted on 2023-02-16
1669 Network-based elucidation of colon cancer drug resistance by phosphoproteomic time-series analysis
Rosenberger, G.; Li, W.; Turunen, M.; He, J.; Subramaniam, P. S.; Pampou, S.; Griffin, A. T.; Karan, C.; Kerwin, P.; Murray, D.; Honig, B.; Liu, Y.; Califano, A.
10.1101/2023.02.15.528736 — systems biology — Posted on 2023-02-16
1671 Oncogenic KrasG12D specific non-covalent small molecule inhibitor reprograms tumor microenvironment and reverses early precursor lesions and in combination with immunotherapy regresses advanced PDAC in a CD8+ T cells dependent manner
Mahadevan, K. K.; McAndrews, K.; LeBleu, V.; Yang, S.; Lyu, H.; Li, B.; Sockwell, A. M.; Kirtley, M. L.; Morse, S. J.; Moreno Diaz, B. M.; Kim, M. P.; Feng, N.; Lopez, A. M.; Guerrero, P. A.; Sugimoto, H.; Arian, K. A.; Ying, H.; Barekatain, Y.; Kelly, P. J.; MAITRA, A.; Heffernan, T. P.; Kalluri, R.
10.1101/2023.02.15.528757 — cancer biology — Posted on 2023-02-16
1678 Assessment of contaminants, health and survival of migratory shorebirds in natural versus artificial wetlands - the potential of wastewater treatment plants as alternative habitats
Ross, T.; Zhang, J.; Wille, M.; Ciesielski, T. M.; Asimakopoulos, A. G.; Lemesle, P.; Skaalvik, T. G.; Atkinson, R.; Jessop, R.; Victorian Wader Study Group, ; Jaspers, V. L. B.; Klaassen, M.
10.1101/2023.02.15.528752 — ecology — Posted on 2023-02-16
1679 Influences of chemotype and parental genotype on metabolic fingerprints of tansy plants uncovered by predictive metabolomics.
Dussarrat, T.; Schweiger, R.; Ziaja, D.; Nguyen, T. T. N.; Krause, L.; Jakobs, R.; Eilers, E. J.; Müller, C.
10.1101/2023.02.16.528607 — ecology — Posted on 2023-02-16
1684 The mitochondrial regulation of smooth muscle cell proliferation in type 2 diabetes
Grumbach, I. M.; Koval, O. M.; Nguyen, E.; Mittauer, D. J.; Ait-Aissa, K.; Chinchankar, W.; Qian, L.; Madesh, M.; Dai, D.-F.
10.1101/2023.02.15.528765 — molecular biology — Posted on 2023-02-16
1687 The EspN transcription factor is an infection-dependent regulator of the ESX-1 system in M. marinum
Nicholson, K. R.; Cronin, R. M.; Menon, A. R.; Jennisch, M. K.; Tobin, D. M.; Champion, P. A.
10.1101/2023.02.15.528779 — microbiology — Posted on 2023-02-16
1688 The oxidative stress response, in particular the katY gene, is temperature-regulated in Yersinia pseudotuberculosis
Scheller, D.; Becker, F.; Wimbert, A.; Meggers, D.; Pienkoss, S.; Twittenhoff, C.; Knoke, L. R.; Leichert, L. I.; Narberhaus, F.
10.1101/2023.02.16.528792 — microbiology — Posted on 2023-02-16
1689 Interleukin 12 correlates with performance, metabolism and acid-base balance during physical exercise
Castilho, I. V.; Goncalves, L. C. O.; Rodolpho, S. G. L.; Lopes, J. S. S.; Franca, E. L.; Franca, A. H.; Magalhaes Neto, A. M. d.
10.1101/2023.02.15.528787 — immunology — Posted on 2023-02-16
1690 Molecular basis for potent B cell responses to antigen displayed on particles of viral size
Brooks, J. F.; Riggs, J.; Mueller, J. L.; Mathenge, R.; Wholey, W.-Y.; Yoda, S.-T.; Vykunta, V.; Cheng, W.; Zikherman, J.
10.1101/2023.02.15.528761 — immunology — Posted on 2023-02-16
1691 Common roles for serotonin in rats and humans for computations underlying flexible decision-making
Luo, Q.; Kanen, J. W.; Bari, A.; Skandali, N.; Langley, C.; Knudsen, G. M.; Alsio, J.; Phillips, B. U.; Sahakian, B. J.; Cardinal, R. N.; Robbins, T. W.
10.1101/2023.02.15.527569 — neuroscience — Posted on 2023-02-16
1692 SorCS2 modulates neurovascular coupling via glutamatergic and calcium signaling in astrocytes
Staehr, C.; Login, H.; Postnov, D. D.; Ardestani, S. B.; Nolte, S. S.; Beck, H. C.; Nykjaer, A.; Matchkov, V. V.
10.1101/2023.02.16.528727 — neuroscience — Posted on 2023-02-16
1694 Highly sensitive in vivo detection of dynamic changes in enkephalins following acute stress
Mikati, M. O.; Erdmann-Gilmore, P.; Connors, R.; Conway, S. M.; Malone, J.; Woods, J.; Sprung, R. W.; Townsend, R. R.; Al-Hasani, R.
10.1101/2023.02.15.528745 — neuroscience — Posted on 2023-02-16
1697 E2F1 Mediates SOX17 Deficiency-Induced Pulmonary Hypertension
Yi, D.; Liu, B.; Ding, H.; Li, S.; Li, R.; Pan, J.; Ramirez, K.; Xia, X.; Kala, M.; Singh, I.; Ye, Q.; Lee, W. H.; Frye, R.; Wang, T.; Zhao, Y.; Knox, K.; Glembotski, C.; Fallon, M.; Dai, Z.
10.1101/2023.02.15.528740 — physiology — Posted on 2023-02-16
1698 Cancer Prevalence Across Vertebrates
Compton, Z. T.; Harris, V.; Mellon, W.; Rupp, S.; Mallo, D.; Kapsetaki, S.; Wilmot, M.; Kennington, R.; Noble, K.; Baciu, C.; Ramirez, L.; Peraza, A.; Martins, B.; Sudhakar, S.; Aksoy, S.; Furukawa, G.; Vincze, O.; Giraudeau, M. T.; Duke, E.; Spiro, S.; Flach, E.; Davidson, H.; Zehnder, A.; Graham, T. A.; Troan, B.; Harrison, T.; Tollis, M.; Schiffman, J.; Aktipis, A.; Abegglen, L.; Maley, C.; Boddy, A.
10.1101/2023.02.15.527881 — cancer biology — Posted on 2023-02-16
1699 A critical role of VEGFR2 in lymphatic tumor metastasis
Li, T.; Cao, X.; Zhou, F.; Cui, J.; Xu, B.; Li, X.; Claesson-Welsh, L.; Makinen, T.; He, Y.
10.1101/2023.02.16.528814 — cancer biology — Posted on 2023-02-16
1700 Eddy current-induced artifacts correction in high gradient strength diffusion MRI with dynamic field monitoring: demonstration in ex vivo human brain imaging
Ramos Llorden, G.; Park, D.; Kirsch, J. E.; Scholz, A.; Keil, B.; Maffei, C.; Lee, H.-H.; Bilgic, B.; Edlow, B.; Mekkaoui, C.; Yendiki, A.; Witzel, T.; Huang, S. Y.
10.1101/2023.02.15.528684 — bioengineering — Posted on 2023-02-16
1701 Automatic Abdominal Multi Organ Segmentationusing Residual UNet
Murugesan, G. K.; McCrumb, D.; Brunner, E.; Kumar, J.; Soni, R.; Grigorash, V.; Chang, A.; Peck, A.; VanOss, J.; Moore, S.
10.1101/2023.02.15.528755 — bioengineering — Posted on 2023-02-16
1703 Finite Element Modeling of Residual Hearing after Cochlear Implant Surgery in Chinchillas
Castle, N.; Liang, J.; Smith, M.; Petersen, B.; Matson, C.; Eldridge, T.; Zhang, K.; Lee, C.-H.; Liu, Y.; Dai, C.
10.1101/2023.02.15.528713 — bioengineering — Posted on 2023-02-16
1705 Structural basis for lysophosphatidylserine recognition by GPR34
Izume, T.; Kawahara, R.; Uwamizu, A.; Chen, L.; Yaginuma, S.; Omi, J.; Kawana, H.; Sano, F. K.; Tanaka, T.; Kobayashi, K.; Okamoto, H. H.; Kise, Y.; Ohwada, T.; Aoki, J.; Shihoya, W.; Nureki, O.
10.1101/2023.02.15.528751 — biochemistry — Posted on 2023-02-16
1707 Spatial transcriptomic analysis of Sonic Hedgehog Medulloblastoma identifies that the loss of heterogeneity and promotion of differentiation underlies the response to CDK4/6 inhibition
Vo, T.; Balderson, B.; Jones, K.; Ni, G.; Crawford, J.; Millar, A.; Tolson, E.; Singleton, M.; Mulay, O.; Walters, S.; Robertson, T.; Bhuva, D. D.; Davis, M. J.; Wainwright, B. J.; Nguyen, Q.; Genovesi, L. A.
10.1101/2023.02.15.528116 — genomics — Posted on 2023-02-16
1711 Functional significance of PUF partnerships in C. elegans germline stem cells
Ferdous, A. S.; Costa Dos Santos, S. J.; Kanzler, C. R.; Shin, H.; Carrick, B. H.; Crittenden, S. L.; Wickens, M.; Kimble, J.
10.1101/2023.02.15.528708 — developmental biology — Posted on 2023-02-16
1713 Evolution of the ribbon-like organization of the Golgi apparatus in animal cells
Benvenuto, G.; Leone, S.; Astoricchio, E.; Bormke, S.; Jasek, S.; D'Aniello, E.; Kittelmann, M.; McDonald, K.; Hartenstein, V.; Baena, V.; Escriva, H.; Bertrand, S.; Schierwater, B.; Burkhardt, P.; Ruiz-Trillo, I.; Jekely, G.; Ullrich-Luter, J.; Luter, C.; D'Aniello, S.; Arnone, M. I.; Ferraro, F.
10.1101/2023.02.16.528797 — cell biology — Posted on 2023-02-16
1715 Visualizing H2O2 and NO in endothelial cells: strategies and pitfalls
Altun, H. Y.; Secilmis, M.; Akgul Caglar, T.; Vatandaslar, E.; Ozturk, G.; Vilain, S. P.; Eroglu, E.
10.1101/2023.02.15.528776 — cell biology — Posted on 2023-02-16
1716 DNA 5-methylcytosine regulates genome-wide formation of G-quadruplex structures
Niu, K.; Xiang, L.; Li, X.; Li, J.; Li, Y.; Zhang, C.; Liu, J.; Zhang, X.; Peng, Y.; Xu, G.; Xiang, H.; Wang, H.; Song, Q.; Feng, Q.
10.1101/2023.02.16.528796 — molecular biology — Posted on 2023-02-16
1717 A large-scale serological survey in pets from October 2020 through June 2021 in France shows significantly higher exposure to SARS-CoV-2 in cats
Fritz, M.; Elguero, E.; Becquart, P.; de Riols de Fonclare, D.; Garcia, D.; Beurlet, S.; Denolly, S.; Boson, B.; Rosolen, S. G.; Cosset, F.-L.; Briend-Marchal, A.; Legros, V.; Leroy, E. M.
10.1101/2022.12.23.521567 — microbiology — Posted on 2023-02-16
1718 Spatial heterogeneity in biofilm metabolism elicited by local control of phenazinemethylation
Evans, C. R.; Smiley, M. K.; Thio, S. A.; Wei, M.; Price-Whelan, A. M.; Min, W.; Dietrich, L. E.
10.1101/2023.02.15.528762 — microbiology — Posted on 2023-02-16
1720 C9orf72 poly(PR) mediated neurodegeneration is associated with nucleolar stress
Cicardi, M. E.; Hallgren, J.; Darilang, M.; Krishnamurthy, K.; Shamamandri Markandaiah, S.; Nelson, A. T.; Kankate, V.; Anderson, E.; Pasinelli, P.; Pandey, U. B.; Eischen, C. M.; Trotti, D.
10.1101/2023.02.16.528809 — neuroscience — Posted on 2023-02-16
1721 Inter-laboratory comparison of plant volatile analyses in the light of intra-specific chemodiversity
Eckert, S.; Eilers, E. J.; Jakobs, R.; Anaia, R. A.; Aragam, K. S.; Bloss, T.; Popp, M.; Sasidharan, R.; Schnitzler, J.-P.; Stein, F.; Steppuhn, A.; Unsicker, S. B.; van Dam, N. M.; Yepes, S.; Ziaja, D.; Mueller, C.
10.1101/2023.02.15.528472 — plant biology — Posted on 2023-02-16
1725 Copper drives prion protein phase separation and modulates aggregation
Do Amaral, M. J.; Passos, A. R.; Mohapatra, S.; Da Silva, T. S. L.; Carvalho, R. S.; Almeida, M. d. S.; Pinheiro, A. d. S.; Wegmann, S.; Cordeiro, Y.
10.1101/2023.02.15.528739 — biophysics — Posted on 2023-02-16
1727 μ-PBWT: Enabling the Storage and Use of UK Biobank Data on a Commodity Laptop
Cozzi, D.; Rossi, M.; Rubinacci, S.; Köppl, D.; Boucher, C.; Bonizzoni, P.
10.1101/2023.02.15.528658 — bioinformatics — Posted on 2023-02-16
1731 Gut Microbiome Composition Reveals the Distinctiveness between the Bengali people and the Indigenous Ethnicities in Bangladesh
Ahammad, I.; Rahman, A.; Chowdhury, Z. M.; Bhattacharjee, A.; Dewan, G.; Talukder, S.; Das, K. C.; Keya, C. A.; Hossain, M. U.; Salimullah, M.
10.1101/2023.02.15.528648 — genomics — Posted on 2023-02-16
1732 Transcriptional read through interrupts boundary function in Drosophila
Georgiev, P.; Kyrchanova, O.; Sokolov, V.; Tikhonov, M.; Schedl, P.
10.1101/2023.02.16.528790 — genetics — Posted on 2023-02-16
1735 Evidence for an aquatic origin of influenza virus and the order Articulavirales
Petrone, M. E.; Parry, R.; Mifsud, J. C.; Van Brussel, K.; Vorhees, I.; Richards, Z. T.; Holmes, E. C.
10.1101/2023.02.15.528772 — evolutionary biology — Posted on 2023-02-16
1736 Linking genotypic and phenotypic changes in the LTEE using metabolomics
Favate, J. S.; Skalenko, K. S.; Chiles, E.; Su, X.; Yadavalli, S. S.; Shah, P.
10.1101/2023.02.15.528756 — evolutionary biology — Posted on 2023-02-16
1739 The Pathfinder plasmid toolkit for genetically engineering newly isolated bacteria enables the study of Drosophila-colonizing Orbaceae
Elston, K. M.; Phillips, L. E.; Leonard, S.; Young, E.; Holley, J.-a. C.; Ahsanullah, T.; McReynolds, B.; Moran, N. A.; Barrick, J. E.
10.1101/2023.02.15.528778 — microbiology — Posted on 2023-02-16
1743 Enhanced protein secretion in reduced genome strains of Streptomyces lividans
Hamed, M. B.; Busche, T.; Simoens, K.; Carpentier, S.; Kormanec, J.; Van Mellaert, L.; Kalinowski, J.; Bernaerts, K.; Karamanou, S.; Economou, A.
10.1101/2023.02.14.528591 — systems biology — Posted on 2023-02-16
1744 Generative Molecular Design and Experimental Validation of Selective Histamine H1 Inhibitors
McLoughlin, K. S.; Shi, D.; Mast, J. E.; Bucci, J.; Williams, J. P.; Jones, W. D.; Miyao, D.; Nam, L.; Osswald, H. L.; Zegelman, L.; Allen, J. E.; Bennion, B. J.; Paulson, A. K.; Abagyan, R.; Head, M. S.; Brase, J. M.
10.1101/2023.02.14.528391 — pharmacology and toxicology — Posted on 2023-02-16
1748 Optical tools for visualizing and controlling human GLP-1 receptor activation with high spatiotemporal resolution
Duffet, L.; Williams, E. T.; Gresch, A.; Chen, S.; Bhat, M. A.; Benke, D.; Hartrampf, N.; Patriarchi, T.
10.1101/2023.02.14.528498 — biochemistry — Posted on 2023-02-16
1751 Prdm16 and Vcam1 regulate the postnatal disappearance of embryonic radial glia and the ending of cortical neurogenesis
Li, J.; Godoy, M. I.; Zhang, A. J.; Diamante, G.; Ahn, I. S.; Cebrian-Silla, A.; Alvarez-Buylla, A.; Yang, X.; Novitch, B.; Zhang, Y.
10.1101/2023.02.14.528567 — neuroscience — Posted on 2023-02-16
1752 CRB3 navigates Rab11 trafficking vesicles to promote γTuRC assembly during ciliogenesis
Wang, B.; Liang, Z.; Tan, T.; Zhang, M.; Jiang, Y.; Shang, Y.; Gao, X.; Song, S.; Wang, R.; Chen, H.; Liu, J.; Li, J.; Ren, Y.; Liu, P.
10.1101/2023.02.15.528649 — cell biology — Posted on 2023-02-16
1753 A structured evaluation of genome-scale constraint-based modeling tools for microbial consortia
Scott, W. T.; Benito Vaquerizo, S.; Zimmermann, J.; Bajic, D.; Heinken, A.; Suarez-Diez, M.; Schaap, P. J.
10.1101/2023.02.08.527721 — systems biology — Posted on 2023-02-16
1756 Restructuring of olfactory representations in the fly brain around odor relationships in natural sources
Yang, J.-Y.; O'Connell, T. F.; Hsu, W.-M. M.; Bauer, M. S.; Dylla, K. V.; Sharpee, T. O.; Hong, E. J.
10.1101/2023.02.15.528627 — neuroscience — Posted on 2023-02-16
1761 Pharmacological PINK1 activation ameliorates Pathology in Parkinson's Disease models
Chin, R. M.; Rakhit, R.; Ditsworth, D.; Wang, C.; Bartholomeus, J.; Liu, S.; Mody, A.; Laihsu, A.; Eastes, A.; Tai, C.; Kim, R.; Li, J.; Hansberry, S.; Khasnavis, S.; Rafalski, V.; Heerendeen, D.; Garda, V.; Phung, J.; de Roulet, D.; Ordureau, A.; Harper, J. W.; Johnstone, S.; Stoehr, J.; Hertz, N. T.
10.1101/2023.02.14.528378 — neuroscience — Posted on 2023-02-15
1765 Neuronal Transcriptome Disruption, Tau Accumulation and Synapse Loss in Alzheimer's Knock-in Mice Require Cellular Prion Protein
Stoner, A.; Fu, L.; Nicholson, L.; Zheng, C.; Toyonaga, T.; Spurrier, J.; Laird, W.; Cai, Z.; Strittmatter, S. M.
10.1101/2023.02.15.528700 — neuroscience — Posted on 2023-02-15
1766 Smurfness-based two-phase model of ageing helps deconvolve the ageing transcriptional signature
Zane, F.; Bouzid, H.; Sosa Marmol, S.; Brazane, M.; Besse, S.; Molina, J. L.; Cansell, C.; Aprahamian, F.; Durand, S.; Ayache, J.; Antoniewski, C.; Todd, N.; Rera, M.
10.1101/2022.11.22.517330 — systems biology — Posted on 2023-02-15
1767 CRACD, a gatekeeper restricting proliferation, heterogeneity, and immune evasion of small cell lung cancer
Zhang, S.; Kim, K.-B.; Huang, Y.; Kim, D.-W.; Kim, B.; Ko, K.-P.; Zou, G.; Zhang, J.; Jun, S.; Kirk, N. A.; Hwang, Y. E.; Ban, Y. H.; Chan, J. M.; Rudin, C. M.; PARK, K.-S.; Park, J.-I.
10.1101/2023.02.15.528365 — cancer biology — Posted on 2023-02-15
1768 Lipid nanoparticle structure and delivery route during pregnancy dictates mRNA potency, immunogenicity, and health in the mother and offspring
Chaudhary, N.; Newby, A. N.; Arral, M. L.; Yerneni, S. S.; LoPresti, S. T.; Doerfler, R.; Petersen, D. M. S.; Fox, B.; Coon, T.; Malaney, A.; Sadovsky, Y.; Whitehead, K. A.
10.1101/2023.02.15.528720 — bioengineering — Posted on 2023-02-15
1769 Sustained Delivery of GLP-1 Receptor Agonists from Injectable Biomimetic Hydrogels Improves Treatment of Diabetes
d'Aquino, A. I.; Maikawa, C. L.; Nguyen, L. T.; Lu, K.; Hall, I. A.; Prossnitz, A. N.; Chang, E.; Baker, S. W.; Kasse, C. I.; Jons, C. K.; Yan, J.; Hovgaard, L.; Steensgaard, D. B.; Andersen, H. B.; Simonsen, L.; Appel, E. A.
10.1101/2023.01.28.526057 — bioengineering — Posted on 2023-02-15
1773 Metformin impairs trophoblast metabolism and differentiation in dose dependent manner
Nashif, S. K.; Mahr, R. M.; Jena, S.; Jo, S.; Nelson, A. B.; Sadowski, D.; Crawford, P. A.; Puchalska, P.; Alejandro, E. U.; Gearhart, M. D.; Wernimont, S. A.
10.1101/2023.02.14.528531 — cell biology — Posted on 2023-02-15
1774 A novel rotavirus reverse genetics platform supports flexible insertion of exogenous genes and enables rapid development of a high-throughput neutralization assay
Wei, J.; Radcliffe, S.; Lu, M.; Li, Y.; Cassaday, J.; Newhard, W.; Heidecker, G. J.; Rose, W.; He, X.; Freed, D.; Citron, M.; Espeseth, A.; Wang, D.
10.1101/2023.02.15.528690 — microbiology — Posted on 2023-02-15
1777 Prefrontal network engagement by deep brain stimulation in limbic hubs
Allawala, A. B.; Bijanki, K. R.; Oswalt, D.; Mathura, R.; Adkinson, J.; Pirtle, V.; Shofty, B.; Robinson, M. E.; Harrison, M. T.; Mathew, S. J.; Goodman, W. K.; Pouratian, N.; Sheth, S.; Borton, D. A.
10.1101/2022.09.08.507155 — neuroscience — Posted on 2023-02-15
1779 Metabolic competition between lipid metabolism and histone methylation regulates sexual differentiation in human malaria parasites.
Harris, C. T.; Tong, X.; Campelo Morillo, R.; Vanheer, L. N.; Marreiros, I. M.; Nahiyaan, N.; Zuzarte-Luis, V. A.; Deitsch, K. W.; Mota, M. M.; Rhee, K. Y.; Kafsack, B. F. C.
10.1101/2022.01.18.476397 — systems biology — Posted on 2023-02-15
1780 Botrytis cinerea small RNAs are associated with tomato AGO1 and silence tomato defense-related target genes supporting cross-kingdom RNAi
He, B.; Cai, Q.; Weiberg, A.; Li, W.; Chen, A.-P.; Ouyang, S.; Borkovich, K.; Stajich, J.; Abreu-Goodger, C.; Jin, H.
10.1101/2022.12.30.522274 — plant biology — Posted on 2023-02-15
1781 Novel Class of Psychedelic Iboga Alkaloids Disrupts Opioid Addiction States
Havel, V.; Kruegel, A. C.; Bechand, B.; McIntosh, S.; Stallings, L.; Hodges, A.; Wulf, M. G.; Nelson, M.; Hunkele, A.; Ansonoff, M.; Pintar, J. E.; Hwu, C.; Abi-Gerges, N.; Zaidi, S. A.; Katritch, V.; Yang, M.; Javitch, J. A.; Majumdar, S.; Hemby, S. E.; Sames, D.
10.1101/2021.07.22.453441 — pharmacology and toxicology — Posted on 2023-02-15
1782 The methyltransferases METTL7A and METTL7B confer resistance to thiol-based histone deacetylase inhibitors
Robey, R. W.; Fitzsimmons, C. M.; Guiblet, W. M.; Frye, W. J. E.; Gonzalez Dalmasy, J.; Wang, L.; Russell, D. A.; Huff, L. M.; Perciaccante, A. J.; Ali-Rahmani, F.; Lipsey, C. C.; Wade, H. M.; Mitchell, A. V.; Maligireddy, S. S.; Terrero, D.; Butcher, D.; Edmondson, E. F.; Jenkins, L. M.; Nikitina, T.; Zhurkin, V. B.; Tiwari, A. K.; Piscopio, A. D.; Totah, R. A.; Bates, S. E.; Arda, H. E.; Gottesman, M. M.; Batista, P. J.
10.1101/2022.10.07.511310 — cancer biology — Posted on 2023-02-15
1785 Patterns of gene expression and allele-specific expression vary among macular tissues and clinical stages of Age-related Macular Degeneration
Zhang, C.; Barr, J. L.; Owen, L. A.; Shakoor, A.; Vitale, A.; Lillvis, J. H.; Husami, N.; Cromwell, P.; Finley, R.; Au, E.; Haider, N. B.; Zavala, R. A.; Graves, E. C.; Li, M.; Tawkif, A.; Zhang, S. X.; Stambolian, D.; Farkas, M. H.; Kim, I. K.; Sherva, R.; Farrer, L.; DeAngelis, M. M.
10.1101/2022.12.19.521092 — genomics — Posted on 2023-02-15
1786 Selective loss of specific subsets of hair cell and spiral ganglion cell types in an outbred mouse model of age-related hearing loss
Boussaty, E. C.; Tedeschi, N.; Novotny, M.; Ninoyu, Y.; Du, E.; Draf, C.; Zhang, Y.; Scheuermann, R. H.; Friedman, R. A.
10.1101/2023.02.15.528661 — genomics — Posted on 2023-02-15
1788 Neanderthal Introgression Shaped Human Circadian Traits
Velazquez-Arcelay, K.; Colbran, L. L.; McArthur, E.; Brand, C. M.; Siemann, J. K.; McMahon, D. G.; Capra, J. A.
10.1101/2023.02.03.527061 — evolutionary biology — Posted on 2023-02-15
1789 Scanning electron microscopy of human islet cilia
Polino, A. J.; Sviben, S.; Melena, I.; Piston, D. W.; HUGHES, J.
10.1101/2023.02.15.528685 — cell biology — Posted on 2023-02-15
1790 Regulatory principles of human mitochondrial gene expression revealed by kinetic analysis of the RNA life cycle
McShane, E.; Couvillion, M.; Ietswaart, R.; Prakash, G.; Smalec, B. M.; Soto, I.; Baxter-Koenigs, A. R.; Choquet, K.; Churchman, L. S.
10.1101/2023.02.09.527880 — cell biology — Posted on 2023-02-15
1792 Semi-conservative transmission of DNA N6-adenine methylation in a unicellular eukaryote
Sheng, Y.; Wang, Y.; Yang, W.; Wang, X. Q.; Lu, J.; Pan, B.; Nan, B.; Liu, Y.; Li, C.; Song, J.; Dou, Y.; Gao, S.; Liu, Y.
10.1101/2023.02.15.468708 — molecular biology — Posted on 2023-02-15
1793 smalldisco, a pipeline for siRNA discovery and 3' tail identification
Vasconcellos Caldas, I.; Kelley, L. H.; Ahmed-Braimah, Y. H.; Maine, E. M.
10.1101/2022.07.15.500275 — molecular biology — Posted on 2023-02-15
1796 Low Gut Microbial Diversity Augments Estrogen-driven Pulmonary Fibrosis in Female-Predominant Interstitial Lung Disease
Chioma, O. S.; Mallott, E.; Bandhi, B. S.; Wiggins, Z.; Langford, M.; Lancaster, A. W.; Gelbard, A.; Wu, H.; Johnson, J.; Lancaster, L.; Wilfong, E.; Crofford, L. J.; Montgomery, C.; Van Kaer, L.; Bordenstein, S.; Newcomb, D.; Drake, W.
10.1101/2023.02.15.528630 — immunology — Posted on 2023-02-15
1797 Mixed IgG Fc immune complexes exhibit blended binding profiles and refine FcR affinity estimates
Tan, Z. C.; Lux, A.; Biburger, M.; Varghese, P.; Lees, S.; Nimmerjahn, F.; Meyer, A. S.
10.1101/2023.02.15.528730 — immunology — Posted on 2023-02-15
1798 Maternal group 2 innate lymphoid cells control fetal growth and protect from endotoxin-induced abortion in mice
Balmas, E.; Rana, B. M.; Hamilton, R. S.; Shreeve, N.; Kieckbusch, J.; Aye, I.; Hawkes, D. A.; Trotter, S.; Lopez-Trello, J.; Yong, H. E.; Valenti, S.; Sferruzzi-Perri, A. N.; Gaccioli, F.; McKenzie, A. N.; Colucci, F.
10.1101/348755 — immunology — Posted on 2023-02-15
1799 Vascular oxidative stress causes neutrophil arrest in brain capillaries, leading to decreased cerebral blood flow and contributing to memory impairment in a mouse model of Alzheimer's disease
Ruiz-Uribe, N. E.; Bracko, O.; Swallow, M.; Omurzakov, A.; Dash, S.; Uchida, H.; Xiang, D.; Haft-Javaherian, M.; Falkenhain, K.; Lamont, M. E.; Ali, M.; Njiru, B. N.; Chang, H.-Y.; Tan, A. Y.; Xiang, J. Z.; Iadecola, C.; Park, L.; Sanchez, T.; Nishimura, N.; Schaffer, C. B.
10.1101/2023.02.15.528710 — neuroscience — Posted on 2023-02-15
1800 Probing different paradigms of morphine withdrawal on sleep behavior in male and female C57BL/6J mice
Bedard, M. L.; Lord, J. S.; Perez, P. J.; Bravo, I. M.; Teklezghi, A. T.; Tarantino, L. M.; Diering, G. H.; McElligott, Z. A.
10.1101/2022.04.06.487380 — neuroscience — Posted on 2023-02-15
1801 Exogenous Sex Hormone Effects on Brain Microstructure in Women: A Diffusion MRI Study in the UK Biobank
Nabulsi, L.; Lawrence, K. E.; Santhalingam, V.; Abaryan, Z.; Boyle, C. P.; Villalon-Reina, J. E.; Nir, T. M.; Ba Gari, I.; Zhu, A. H.; Haddad, E.; Muir, A. M.; Jahanshad, N.; Thompson, P. M.
10.1101/2020.09.18.304154 — neuroscience — Posted on 2023-02-15
1803 In situ architecture of Opa1-dependent mitochondrial cristae remodeling
Fry, M. Y.; Navarro, P. P.; Qin, X.; Inde, Z.; Ananda, V. Y.; Lugo, C. M.; Hakim, P.; Luce, B. E.; Ge, Y.; McDonald, J. L.; Ali, I.; Ha, L. L.; Kleinstiver, B. P.; Chan, D. C.; Sarosiek, K.; Chao, L. H.
10.1101/2023.01.16.524176 — biophysics — Posted on 2023-02-15
1809 Massively parallel characterization of psychiatric disorder-associated and cell-type-specific regulatory elements in the developing human cortex
Deng, C.; Whalen, S.; Steyert, M.; Ziffra, R.; Przytycki, P. F.; Inoue, F.; Pereira, D. A.; Capauto, D.; Norton, S.; Vaccarino, F. M.; Pollen, A. A.; Nowakowski, T. J.; Ahituv, N. A.; Pollard, K. S.
10.1101/2023.02.15.528663 — genomics — Posted on 2023-02-15
1810 Gene body DNA hydroxymethylation restricts the magnitude of transcriptional changes during aging
Occean, J. R.; Yang, N.; Sun, Y.; Dawkins, M. S.; Munk, R.; Belair, C.; Dar, S.; Anerillas, C.; Wang, L.; Shi, C.; Dunn, C.; Bernier, M.; Price, N. L.; Kim, J. S.; Cui, C.-Y.; Fan, J.; Bhattacharyya, M.; De, S.; Maragkakis, M.; Cabo, R. d.; Sidoli, S.; Sen, P.
10.1101/2023.02.15.528714 — genomics — Posted on 2023-02-15
1812 Temporal Notch signaling regulates mucociliary cell fates through Hes-mediated competitive de-repression
Brislinger-Engelhardt, M. M.; Lorenz, F.; Haas, M.; Bowden, S.; Tasca, A.; Kreutz, C.; Walentek, P.
10.1101/2023.02.15.528675 — developmental biology — Posted on 2023-02-15
1813 Assessing the performance of the Cell Painting assay across different imaging systems
Jamali, N.; Tromans-Coia, C.; Abbasi, H. S.; Giuliano, K. A.; Hagimoto, M.; Jan, K.; Kaneko, E.; Letzsch, S.; Schreiner, A.; Sexton, J. Z.; Suzuki, M.; Trask, O. J.; Yamaguchi, M.; Yanagawa, F.; Yang, M.; Carpenter, A. E.; Cimini, B. A.
10.1101/2023.02.15.528711 — cell biology — Posted on 2023-02-15
1816 Western diet increases brain metabolism and adaptive immune responses in a mouse model of amyloidosis
Poxleitner, M.; Hoffmann, S. H. L.; Berezhnoy, G.; Ionescu, T.; Gonzalez-Menendez, I.; Maier, F. C.; Seyfried, D.; Ehrlichmann, W.; Quintanilla-Martinez, L.; Schmid, A. M.; Reischl, G.; Trautwein, C.; Maurer, A.; Pichler, B. J.; Herfert, K.; Beziere, N.
10.1101/2023.02.15.528645 — immunology — Posted on 2023-02-15
1818 Boldine modulates glial transcription and functional recovery in a murine model of contusion spinal cord injury
Toro, C. A.; Johnson, K. E.; Hansen, J.; Siddiq, M. M.; Vasquez, W.; Zhao, W.; Graham, Z. A.; Saez, J. C.; Iyengar, R.; Cardozo, C. P.
10.1101/2023.02.15.528337 — neuroscience — Posted on 2023-02-15
1819 The response time paradox in functional magnetic resonance imaging analyses
Mumford, J. A.; Bissett, P. G.; Jones, H. M.; Shim, S.; Rios, J. A. H.; Poldrack, R. A.
10.1101/2023.02.15.528677 — neuroscience — Posted on 2023-02-15
1820 Electroacupuncture prevents astrocyte atrophy to alleviate depression
Lin, S.-S.; Zhou, B.; Chen, B.-J.; Jiang, R.; Li, B.; Illes, P.; Semyanov, A.; Tang, Y.; Verkhratsky, A.
10.1101/2023.02.15.528709 — neuroscience — Posted on 2023-02-15
1822 Amygdala AVPR1A mediates susceptibility to chronic social isolation in females
Francois, M.; Delgado, I. C.; Lafond, A.; Lewis, E.; Kuromaru, M.; Hassouna, R.; Deng, S.; Thaker, V. V.; Dolen, G.; Zeltser, L. M.
10.1101/2023.02.15.528679 — neuroscience — Posted on 2023-02-15
1823 Integrated single cell and unsupervised spatial transcriptomic analysis defines molecular anatomy of the human dorsolateral prefrontal cortex
Huuki-Myers, L. A.; Spangler, A.; Eagles, N. J.; Montgomery, K. D.; Kwon, S. H.; Guo, B.; Grant-Peters, M.; Divecha, H. R.; Tippani, M.; Sriworarat, C.; Nguyen, A. B.; Ravichandran, P.; Tran, M. N.; Seyedian, A.; PsychENCODE Consortium, ; Hyde, T. M.; Kleinman, J. E.; Battle, A.; Page, S. C.; Ryten, M.; Hicks, S. C.; Martinowich, K.; Collado-Torres, L.; Maynard, K. R.
10.1101/2023.02.15.528722 — neuroscience — Posted on 2023-02-15
1824 Intricate epileptiform discharges affect memory in an Alzheimer's Disease mouse model
Soula, M.; Maslarova, A.; Harvey, R. E.; Valero, M.; Brandner, S.; Hamer, H.; Fernandez Ruiz, A.; Buzsaki, G.
10.1101/2023.02.15.528683 — neuroscience — Posted on 2023-02-15
1825 A Single-cell Perturbation Landscape of Colonic Stem Cell Polarisation
Qin, X.; Rodriguez, F. C.; Sufi, J.; Vlckova, P.; Claus, J.; Tape, C. J.
10.1101/2023.02.15.528008 — cancer biology — Posted on 2023-02-15
1827 A Comparison of Quantitative Mass Spectrometric Methods for Drug Target Identification by Thermal Proteome Profiling
George, A. L.; Sidgwick, F. R.; Watt, J. E.; Martin, M. P.; Trost, M.; Marin-Rubio, J. L.; Duenas, M. E.
10.1101/2023.02.15.528618 — biochemistry — Posted on 2023-02-15
1829 Fine-tuning spatial-temporal dynamics and surface receptor expression support plasma cell-intrinsic longevity
Jing, Z.; Galbo, P.; Ovando, L.; Demouth, M.; Welte, S.; Park, R.; Chandran, K.; Wu, Y.; MacCarthy, T.; Zheng, D.; Fooksman, D.
10.1101/2023.02.15.527913 — immunology — Posted on 2023-02-15
1830 De novo fatty-acid synthesis protects invariant NKT cells from cell death, thereby promoting their homeostasis and pathogenic roles in airway hyperresponsiveness
Koh, J.; Woo, Y. D.; Yoo, H. J.; Choi, J.-P.; Kim, S. H.; Chang, Y.-S.; Jung, K. C.; Kim, J. H.; Jeon, Y. K.; Kim, H. Y.; Chung, D. H.
10.1101/2023.02.15.528598 — immunology — Posted on 2023-02-15
1836 Downregulation of stromal syntenin sustains AML development
Leblanc, R.; Ghossoub, R.; Goubard, A.; Castellano, R.; Fares, J.; Camoin, L.; Audebert, S.; Balzano, M.; Boutayeh, B.; Fauriat, C.; Vey, N.; Borg, J.-P.; Collette, Y.; Aurrand-Lions, M.; David, G.; Zimmermann, P.
10.1101/2023.02.15.527799 — cancer biology — Posted on 2023-02-15
1837 Spatio-temporal coherence of circadian clocks and gating of differentiation in Anabaena filaments
Arbel-Goren, R.; Dassa, B.; Zhitnitsky, A.; Valladares, A.; Herrero, A.; Flores, E.; Stavans, J.
10.1101/2023.02.15.528611 — biophysics — Posted on 2023-02-15
1839 Systematic analysis of disease-linked rare germline variants reveals new classes of cancer predisposing genes
Song, S.; Koh, Y.; Kim, S.; Lee, S. M.; Kim, H. U.; Ko, J. M.; Lee, S.-H.; Yoon, S.-S.; Park, S.
10.1101/2023.02.15.528610 — bioinformatics — Posted on 2023-02-15
1843 Flow augmentation from off-channel storage improves salmonid habitat and survival
Rossi, G.; Obedzinski, M.; Pneh, S.; Pierce, S. N.; Boucher, W.; Flynn, K.; Slaughter, W.; Grantham, T.
10.1101/2023.02.15.528508 — ecology — Posted on 2023-02-15
1844 Comprehensive Multi-omics Analysis Reveals the Core Role of Glycerophospholipid Metabolism in Rheumatoid Arthritis Development
Jian, C.; Wei, L.; Wu, T.; Li, S.; Wang, T.; Chen, J.; Chang, S.; Zhang, J.; He, B.; Wu, J.; Su, J.; Zhu, J.; Wu, M.; Zhang, Y.; Zeng, F.
10.1101/2023.02.15.528612 — immunology — Posted on 2023-02-15
1845 Accumulation of Tau in Extracellular Vesicles Disturbs the Astrocytic Mitochondrial System
Perbet, R.; Zufferey, V.; Leroux, E.; Parietti, E.; Espourteille, J.; Culebras, L.; Perriot, S.; Du Pasquier, R.; Begard, S.; Deramecou, V.; Deglon, N.; Toni, N.; Buee, L.; Colin, M.; Richetin, K.
10.1101/2023.02.15.527595 — neuroscience — Posted on 2023-02-15
1847 Top-down specific preparatory activations for Selective Attention and Perceptual Expectations
G. Penalver, J. M.; Lopez-Garcia, D.; Gonzalez-Garcia, C.; Aguado-Lopez, B.; Gorriz, J. M.; Ruz, M.
10.1101/2022.09.13.507583 — neuroscience — Posted on 2023-02-15
1848 Linking structural and functional changes during aging using multilayer brain network analysis
Jauny, G.; Mijalkov, M.; Canal-Garcia, A.; Volpe, G.; Pereira, J. B.; Eustache, F.; Hinault, T. T.
10.1101/2023.02.15.528643 — neuroscience — Posted on 2023-02-15
1849 A novel triptolide analog downregulates NF-κB and induces mitochondrial apoptosis pathways in human pancreatic cancer
Tian, Q.; Zhang, P.; Wang, Y.; Si, Y.; Yin, D.; Weber, C. R.; Fishel, M.; Pollok, K. E.; Qiu, B.; Xiao, F.; Chong, A.
10.1101/2023.02.15.528599 — pharmacology and toxicology — Posted on 2023-02-15
1851 NetSyn: genomic context exploration of protein families
Stam, M.; Langlois, j.; Chevalier, C.; Reboul, G.; Bastard, K.; Medigue, C.; Vallenet, D.
10.1101/2023.02.15.528638 — bioinformatics — Posted on 2023-02-15
1852 Visualization & Quality Control Tools for Large-scale Multiplex Tissue Analysis in TissUUmaps 3
Behanova, A.; Avenel, C.; Andersson, A.; Chelebian, E.; Klemm, A.; Wik, L.; Ostman, A.; Wahlby, C.
10.1101/2022.12.01.518716 — bioinformatics — Posted on 2023-02-15
1853 Architecture and regulation of filamentous humancystathionine beta-synthase
McCorvie, T. J.; Bailey, H. J.; Strain-Damerell, C.; Basle, A.; Yue, W. W.
10.1101/2023.02.15.528523 — biochemistry — Posted on 2023-02-15
1854 Comprehensive single-cell genome analysis at nucleotide resolution using the PTA Analysis Toolbox
Middelkamp, S.; Manders, F.; Peci, F.; van Roosmalen, M. J.; Gonzalez, D. M.; Bertrums, E. J. M.; van der Werf, I.; Derks, L. L. M.; Groenen, N. M.; Verheul, M.; Trabut, L.; Brandsma, A. M.; Antoniou, E.; Reinhardt, D.; Bierings, M.; Belderbos, M. E.; van Boxtel, R.
10.1101/2023.02.15.528636 — genomics — Posted on 2023-02-15
1857 Integration host factor regulates colonization factors in the bee gut symbiont Frischella perrara
Schmidt, K.; Santos-Matos, G.; Leopold-Messer, S.; El Chazli, Y.; Emery, O.; Steiner, T.; Piel, J.; Engel, P.
10.1101/2021.12.06.471457 — microbiology — Posted on 2023-02-15
1860 Restructuring of olfactory representations in the fly brain around odor relationships in natural sources
Yang, J.-Y.; O'Connell, T. F.; Hsu, W.-M. M.; Bauer, M. S.; Dylla, K. V.; Sharpee, T. O.; Hong, E. J.
10.1101/2023.02.15.528627 — neuroscience — Posted on 2023-02-15
1861 An actin-like filament from Clostridium botulinum exhibits a novel mechanism of filament dynamics
Koh, A.; Ali, S.; Popp, D.; Tanaka, K.; Kitaoku, Y.; Miyazaki, N.; Kenji, I.; Mitsuoka, K.; Robinson, R. C.; Narita, A.
10.1101/2022.03.07.483215 — biophysics — Posted on 2023-02-15
1864 Specialized actin nanoscale layers control focal adhesion turnover
Kumari, R.; Ven, K.; Chastney, M.; Peranen, J.; Arron, J.; Almeida-Souza, L.; Kremneva, E.; Poincloux, R.; Chew, T. L.; Gunning, P. W.; Ivaska, J.; Lappalainen, P.
10.1101/2023.02.15.528622 — cell biology — Posted on 2023-02-15
1866 Development and characterization of a multimeric recombinant protein based on the spike protein receptor binding domain of SARS-CoV-2 that can neutralize virus infection
de Lima, V. A.; Ferreira, R. d. S.; Oliva, M. L. V.; Andreata-Santos, R.; Janini, L. M. R.; Maricato, J. T.; Akamatsu, M. A.; Ho, P. L.; Schenkman, S.
10.1101/2023.02.15.528632 — microbiology — Posted on 2023-02-15
1868 Sotrovimab retains activity against SARS-CoV-2 Omicron variant BQ.1.1 in a non-human primate model
Herate, C.; Marlin, R.; Touret, F.; Bosquet, N. D.; Donati, F.; Relouzat, F.; Junges, L.; Galhaut, M.; Dehan, O.; Sconosciutti, Q.; Nougairede, A.; de Lamballerie, X.; van der Werf, S.; Le Grand, R.
10.1101/2023.02.15.528538 — pathology — Posted on 2023-02-15
1869 Predicting CIN rates from single-cell whole genome sequencing data using an in silico model
Bakker, B.; Schubert, M.; Bolhaqueiro, A. C.; Kops, G. J.; Spierings, D. C.; Foijer, F.
10.1101/2023.02.14.528596 — cancer biology — Posted on 2023-02-15
1870 IL-33 drives polyfunctionality and antitumor activity of a unique ST2+ NK cell population
Eberhardt, A.; Blanc, E.; Picant, V.; Alcazer, V.; Rocca, Y.; Ardin, M.; Voissiere, A.; Onodi, F.; Rodriguez, C.; Tonon, L.; Estavoyer, B.; Moudombi, L.; Charrier, E.; Wang, X.; Stojanovic, A.; Rau, T.; Tredan, O.; Treilleux, I.; Michallet, M.-C.; Valladeau-Guilemond, J.; Marcais, A.; Walzer, T.; Krebs, P.; Cerwenka, A.; Hubert, M.; Caux, C.; Bendriss-Vermare, N.
10.1101/2023.02.14.528486 — cancer biology — Posted on 2023-02-15
1871 Borderline rpoB mutations transmit at the same rate as common rpoB mutations in a tuberculosis cohort in Bangladesh
Lempens, P.; Van Deun, A.; Aung, K. J. M.; Hossain, M. A.; Behruznia, M.; Decroo, T.; Rigouts, L.; de Jong, B. C.; Meehan, C. J.
10.1101/2023.02.14.528501 — genomics — Posted on 2023-02-15
1875 CUR(E)ating a New Approach to Study Fungal Effectors and Enhance Undergraduate Education through Authentic Research
Li, G.; McWiliams, M.; Rodrigues, M.; Mearkle, B.; Jaafar, N.; Golla, V.; Yu, H.; Yang, H.; Ayhan, D. H.; Allen, K. S.; Martinez-Soto, D.; Springer, A.; Ma, L.-J.
10.1101/2023.02.14.528535 — scientific communication and education — Posted on 2023-02-15
1877 Genetic control of cell layer interactions in plants via tissue mechanics
Kelly-Bellow, R.; Lee, K.; Kennaway, R.; Barclay, E.; Whibley, A.; Bushell, C.; Spooner, J.; Yu, M.; Brett, P.; Kular, B.; Cheng, S.; Chu, J.; Lane, B.; Fitzsimons, J.; Xue, Y.; Smith, R. S.; Whitewoods, C. D.; Coen, E.
10.1101/2023.02.14.527838 — plant biology — Posted on 2023-02-15
1878 Barley shows reduced Fusarium Head Blight under drought and modular expression of differential expressed genes under combined stress
Hoheneder, F.; Steidele, C. E.; Messerer, M.; Mayer, K.; Koehler, N.; Wurmser, C.; Hess, M.; Gigl, M.; Dawid, C.; Stam, R.; Hueckelhoven, R.
10.1101/2023.02.15.528674 — plant biology — Posted on 2023-02-15
1879 Plasticity of the binding pocket in peptide transporters underpins promiscuous substrate recognition
Kotov, V.; Killer, M.; Jungnickel, K. E. J.; Lei, J.; Finocchio, G.; Steinke, J.; Bartels, K.; Strauss, J.; Dupeux, F.; Humm, A.-S.; Cornaciu, I.; Marquez, J. A.; Pardon, E.; Steyaert, J.; Loew, C.
10.1101/2023.02.14.528348 — biophysics — Posted on 2023-02-15
1880 Rice Gene Index (RGI): a comprehensive pan-genome database for comparative and functional genomics of Asian rice
Yu, Z.; Chen, Y.; Zhou, Y.; Zhang, Y.; Li, M.; Ouyang, Y.; Chebotarov, D.; Mauleon, R.; Zhao, H.; Xie, W.; McNally, K. L.; Wing, R. A.; Guo, W.; Zhang, J.
10.1101/2023.02.14.528456 — genomics — Posted on 2023-02-15
1881 A hyper-quiescent chromatin state formed during aging is reversed by regeneration
Yang, N.; Occean, J. R.; Melters, D. P.; Shi, C.; Wang, L.; Stransky, S.; Doyle, M. E.; Cui, C.-Y.; Delannoy, M.; Fan, J.; Slama, E.; Egan, J. M.; De, S.; Cunningham, S. C.; Cabo, R. d.; Sidoli, S.; Dalal, Y.; Sen, P.
10.1101/2023.02.14.528512 — genomics — Posted on 2023-02-15
1886 Bayesian hierarchical modeling of size spectra
Wesner, J. S.; Pomeranz, J. P. F.; Junker, J. R.; Gjoni, V.; Lio, Y.
10.1101/2023.02.14.528491 — ecology — Posted on 2023-02-15
1888 CRB3 navigates Rab11 trafficking vesicles to promote γTuRC assembly during ciliogenesis
Wang, B.; Liang, Z.; Tan, T.; Zhang, M.; Jiang, Y.; Shang, Y.; Gao, X.; Song, S.; Wang, R.; Chen, H.; Liu, J.; Li, J.; Ren, Y.; Liu, P.
10.1101/2023.02.15.528649 — cell biology — Posted on 2023-02-15
1889 Tertiary Lymphoid Structures Sustain Cutaneous B cell Activity in Hidradenitis Suppurativa
Lowe, M. M.; Cohen, J. N.; Moss, M. I.; Clancy, S.; Adler, J.; Yates, A.; Naik, H. B.; Pauli, M.; Taylor, I.; McKay, A.; Harris, H.; Kim, E.; Hansen, S. L.; Rosenblum, M. D.; Moreau, J. M.
10.1101/2023.02.14.528504 — immunology — Posted on 2023-02-15
1890 Long-term survival and induction of operational tolerance to murine islet allografts through the co-transplantation of cyclosporine A eluting microparticles
Kuppan, P.; Wong, J.; Kelly, S.; Lin, J.; Worton, J.; Castro, C.; Paramor, J.; Seeberger, K.; Anderson, C. C.; Korbutt, G. S.; Pepper, A. R.
10.1101/2023.02.14.528345 — immunology — Posted on 2023-02-15
1892 Pharmacological PINK1 activation ameliorates Pathology in Parkinson's Disease models
Chin, R. M.; Rakhit, R.; Ditsworth, D.; Wang, C.; Bartholomeus, J.; Liu, S.; Mody, A.; Laihsu, A.; Eastes, A.; Tai, C.; Kim, R.; Li, J.; Hansberry, S.; Khasnavis, S.; Rafalski, V.; Heerendeen, D.; Garda, V.; Phung, J.; de Roulet, D.; Ordureau, A.; Harper, J. W.; Johnstone, S.; Stoehr, J.; Hertz, N. T.
10.1101/2023.02.14.528378 — neuroscience — Posted on 2023-02-15
1893 A Theoretical Formalization of Consequence-Based Decision-Making
Cecchini, G.; DePass, M.; Baspinar, E.; Andujar, M.; Ramawat, S.; Pani, P.; Ferraina, S.; Destexhe, A.; Moreno-Bote, R.; Cos, I.
10.1101/2023.02.14.528595 — neuroscience — Posted on 2023-02-15
1896 Tumor Niche Network-Defined Subtypes Predict Immunotherapy Response of Esophageal Squamous Cell Cancer
Ko, K.-P.; Zhang, S.; Huang, Y.; Kim, B.; Zou, G.; Jun, S.; Zhang, J.; Martin, C.; Dunbar, K. J.; Efe, G.; Rustgi, A. K.; Zhang, H.; Nakagawa, H.; Park, J.-I.
10.1101/2023.02.15.528539 — cancer biology — Posted on 2023-02-15
1897 Epigenomic mapping in B-cell acute lymphoblastic leukemia identifies transcriptional regulators and noncoding variants promoting distinct chromatin architectures
Barnett, K. R.; Mobley, R. J.; Diedrich, J. D.; Bergeron, B. P.; Bhattarai, K. R.; Yang, W.; Crews, K. R.; Manring, C. S.; Jabbour, E.; Paietta, E.; Litzow, M. R.; Kornblau, S. M.; Stock, W.; Inaba, H.; Jeha, S.; Pui, C.-H.; Mullighan, C. G.; Relling, M. V.; Yang, J. J.; Evans, W. E.; Savic, D.
10.1101/2023.02.14.528493 — cancer biology — Posted on 2023-02-15
1900 BLINK: Ultrafast tandem mass spectrometry cosine similarity scoring
Harwood, T. V.; Treen, D.; Wang, M.; de Jong, W.; Northen, T.; Bowen, B. P.
10.1101/2023.02.14.528550 — bioinformatics — Posted on 2023-02-15
1904 Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders
Li, Y.-D.; Ma, M. W.; Hassan, M. M.; Hunkeler, M.; Teng, M.; Puvar, K.; Lumpkin, R.; Sandoval, B.; Jin, C. Y.; Ficarro, S. B.; Wang, M. Y.; Xu, S.; Groendyke, B. J.; Sigua, L. H.; Tavares, I.; Zou, C.; Tsai, J. M.; Park, P. M. C.; Yoon, H.; Majewski, F. C.; Marto, J. A.; Qi, J.; Nowak, R. P.; Donovan, K. A.; Slabicki, M.; Gray, N. S.; Fischer, E. S.; Ebert, B. L.
10.1101/2023.02.14.528208 — biochemistry — Posted on 2023-02-15
1905 German Ixodes inopinatus samples may not actually represent this tick species
Rollins, R. E.; Margos, G.; Brachmann, A.; Krebs, S.; Mouchet, A.; Dingemanse, N.; Laatamna, A.; Reghaissia, N.; Fingerle, V.; Metzler, D.; Becker, N. S.; Chitimia-Dobler, L.
10.1101/2023.02.14.528458 — evolutionary biology — Posted on 2023-02-15
1906 The Evolution of Democratic Peace
Hunt, K. L.; Patel, M.; Croft, D. P.; Franks, D. W.; Green, P. A.; Thompson, F. J.; Johnstone, R. A.; Cant, M. A.; Sankey, D. W. E.
10.1101/2023.02.14.528470 — evolutionary biology — Posted on 2023-02-15
1909 Dephosphorylation of 4EBP1/2 Induces Prenatal Neural Stem Cell Quiescence
Geben, L. C.; Brockman, A. A.; Chalkley, M. B. L.; Sweet, S. R.; Gallagher, J. E.; Scheuing, A. L.; Simerly, R. B.; Ess, K. C.; Irish, J. M.; Ihrie, R. A.
10.1101/2023.02.14.528513 — developmental biology — Posted on 2023-02-15
1911 African army ants at the forefront of virome surveillance in a remote tropical forest
Fritz, M.; Reggiardo, B.; Filloux, D.; Claude, L.; Fernandez, E.; Mahe, F.; Kraberger, S.; Custer, J. M.; Becquart, P.; Ndong Mebaley, T.; Bohou Kombila, L.; Lenguiya, L. H.; Boundenga, L.; Mombo, I. M.; Maganga, G. D.; Niama, F. R.; Koumba, J.-S.; Ogliastro, M.; Yvon, M.; Martin, D.; Blanc, S.; Varsani, A.; Leroy, E.; Roumagnac, P.
10.1101/2022.12.13.520061 — microbiology — Posted on 2023-02-15
1913 Cell class-specific electric field entrainment of neural activity
Lee, S. Y.; Baftizadeh, F.; Campagnola, L.; Jarsky, T.; Koch, C.; Anastassiou, C. A.
10.1101/2023.02.14.528526 — neuroscience — Posted on 2023-02-15
1914 High-throughput quantitative screening of glucose-stimulated insulin secretion and insulin content using automated MAL-DI-TOF mass spectrometry
Delannoy, C. P.; Heuson, E.; Herledan, A.; Oger, F.; Thiroux, B.; Chevalier, M.; Gromada, X.; Rolland, L.; Froguel, P.; Deprez, B.; Paul, S.; Annicotte, J.-S.
10.1101/2023.02.14.528514 — physiology — Posted on 2023-02-15
1915 Artificial Intelligence uncovers Evolutionarily Conserved Intracellular Allosteric Modulators of GPCR-Gα interface.
Mohanty, S. K.; Mittal, A.; Gaur, A.; Solanki, S.; Kumar, S.; Duari, S.; Arora, S.; Gautam, V.; Dixit, N. K.; Ghosh, T. S.; Sengupta, D.; Gupta, S. K.; Murugan, N. A.; Ahuja, G.
10.1101/2023.02.14.528587 — bioinformatics — Posted on 2023-02-15
1918 Predicting long-term collective animal behavior with deep learning
Papaspyros, V.; Escobedo, R.; Alahi, A.; Theraulaz, G.; Sire, C.; Mondada, F.
10.1101/2023.02.15.528318 — animal behavior and cognition — Posted on 2023-02-15
1919 Chromosome-level genome assembly of Lilford's wall lizard, Podarcis lilfordi (Gunther, 1874) from the Balearic Islands (Spain)
Gomez-Garrido, J.; Cruz, F.; Alioto, T. S.; Feiner, N.; Uller, T.; Gut, M.; Sanchez Escudero, I.; Tavecchia, G.; Rotger, A.; Otalora Acevedo, K. E.; Baldo, L.
10.1101/2023.02.15.528647 — genomics — Posted on 2023-02-15
1920 The genome of the toxic invasive species Heracleum sosnowskyi carries an increased number of genes despite the absence of recent whole-genome duplications
Schelkunov, M. I.; Shtratnikova, V. Y.; Klepikova, A. V.; Makarenko, M. S.; Omelchenko, D. O.; Novikova, L. A.; Obukhova, E. N.; Bogdanov, V. P.; Penin, A. A. A.; Logacheva, M. D.
10.1101/2023.02.14.528432 — genomics — Posted on 2023-02-15
1922 Natural evolution of SARS-CoV-2 variants in K18-ACE2 mice gives rise to more virulent virus and variant alleles associated with treatment resistance.
Willett, J. D. S.; Gravel, A.; Dubuc, I.; Gudimard, L.; Fortin, P.; Liu, J.-L.; Galvez, J. H.; Zwaig, M.; Roy, A.-M.; Lee, S.; Chen, S.-H.; Ragoussis, I.; Flamand, L.
10.1101/2023.01.16.523994 — genetics — Posted on 2023-02-15
1926 Distinctive in vitro phenotypes in iPSC-derived neurons from patients with gain- and loss-of-function SCN2A developmental and epileptic encephalopathy
Mao, M.; Mattei, C.; Rollo, B.; Byars, S. G.; Cuddy, C.; Berecki, G.; Heighway, J.; Pachernegg, S.; Menheniott, T.; Apted, D.; Jia, L.; Dalby, K.; Nemiroff, A.; Mullen, S.; Reid, C.; Maljevic, S.; Petrou, S.
10.1101/2023.02.14.528217 — neuroscience — Posted on 2023-02-15
1927 Nuclear Factor-Y is a Pervasive Regulator of Neuronal Gene Expression
Moreira, P.; Papatheodorou, P.; Deng, S.; Gopal, S.; Handley, A.; Powell, D.; Pocock, R.
10.1101/2023.02.14.528575 — neuroscience — Posted on 2023-02-15
1929 Stimulus novelty uncovers coding diversity in visual cortical circuits
Garrett, M.; Groblewski, P.; Piet, A.; Ollerenshaw, D.; Yavorska, I.; Najafi, F.; Amster, A.; Bennett, C.; Buice, M.; Caldejon, S.; Casal, L.; D'Orazi, F.; Daniel, S.; de Vries, S. E.; Kapner, D.; Kiggins, J.; Lecoq, J.; Ledochowitsch, P.; Manavi, S.; Mei, N.; Morrison, C. B.; Naylor, S.; Orlova, N.; Perkins, J.; Ponvert, N.; Roll, C.; Seid, S.; Williams, D.; Williford, A.; Ahmed, R.; Amine, D.; Billeh, Y.; Bowman, C.; Cain, N.; Cho, A.; Dawe, T.; Departee, M.; Desoto, M.; Feng, D.; Gale, S.; Gelfand, E.; Gradis, N.; Grasso, C.; Hancock, N.; Hu, B.; Hytnen, R.; Jia, X.; Johnson, T.; Kato, I.;
10.1101/2023.02.14.528085 — neuroscience — Posted on 2023-02-15
1934 Identifying Spatial Co-occurrence in Healthy and InflAmed tissues (ISCHIA)
Lafzi, A.; Borrelli, C.; Bach, K.; Kretz, J. A.; Handler, K.; Regan-Komito, D.; Ficht, X.; Frei, A. P.; Moor, A. E.
10.1101/2023.02.13.526554 — systems biology — Posted on 2023-02-15
1935 Agricultural pesticides do not suppress infection of Biomphalaria (Gastropoda) by Schistosoma mansoni (Trematoda)
Ganatra, A.; Becker, J. M.; Shahid, N.; Kaneno, S.; Hollert, H.; Liess, M.; Agola, E. L.; McOdimba, F.; Fillinger, U.
10.1101/2023.02.13.528426 — systems biology — Posted on 2023-02-15
1937 Insulin-mTOR hyperfunction drives C. elegans aging opposed by the megaprotein LPD-3
Pandey, T.; Wang, B.; Zu, J.; Deng, H.; Shen, K.; Vale, G.; McDonald, J. G.; Ma, D. K.
10.1101/2023.02.14.528431 — physiology — Posted on 2023-02-15
1938 Short-term Topiramate treatment prevents radiation-induced cytotoxic edema in preclinical models of breast-cancer brain metastasis
Contreras-Zarate, M. J.; Alvarez, K. L.; Jaramillo-Gomez, J. A.; Littrell, Z.; Tsuji, N.; Ormond, D. R.; Karam, S. D.; Kabos, P.; Cittelly, D. M.
10.1101/2023.02.14.528559 — cancer biology — Posted on 2023-02-15
1939 CD4 T cells and neutrophils contribute to epithelial-mesenchymal transition in breast cancer
Sanlaville, A.; Voissiere, A.; Poujol, D.; Hubert, M.; Andre, S.; Perret, C.; Foy, J.-P.; Goutagny, N.; Malfroy, M.; Durand, I.; Chalons, M.; Valladeau-Guilemond, J.; Saintigny, P.; Puisieux, A.; Caux, C.; Michallet, M.-C.; Puisieux, I.; Bendriss-Vermare, N.
10.1101/2023.02.15.528594 — cancer biology — Posted on 2023-02-15
1942 The Energetics and Ion Coupling of Cholesterol Transport Through Patched1
Ansell, B.; Corey, R. A.; Viti, L. V.; Kinnebrew, M.; Rohatgi, R.; Siebold, C.; Sansom, M.
10.1101/2023.02.14.528445 — biophysics — Posted on 2023-02-15
1948 Pairtools: from sequencing data to chromosome contacts
Open2C, ; Abdennur, N.; Fudenberg, G.; Flyamer, I. M.; Galitsyna, A. A.; Goloborodko, A.; Imakaev, M.; Venev, S. V.
10.1101/2023.02.13.528389 — bioinformatics — Posted on 2023-02-15
1952 SynEcoSys: a multifunctional platform of large-scale single-cell omics data analysis
Zhang, Y.; Li, B.; Duan, J.; Chen, X.; Zhang, X.; Ye, J.; Veloso, A.; Fan, J.; Fang, N.
10.1101/2023.02.14.528566 — bioinformatics — Posted on 2023-02-15
1953 A Systematic Benchmark of Machine Learning Methods for Protein-RNA Interaction Prediction
Horlacher, M.; Cantini, G.; Hesse, J.; Schinke, P.; Goedert, N.; Londhe, S.; Moyon, L.; Marsico, A.
10.1101/2023.02.14.528560 — bioinformatics — Posted on 2023-02-15
1955 Multivariate Residualization in Medical Imaging Analysis
Donovan, K. M.; Tustison, N. J.; Linn, K. A.; Shinohara, R. T.
10.1101/2023.02.15.528657 — bioinformatics — Posted on 2023-02-15
1956 Designed Transmembrane Proteins Inhibit the Erythropoietin Receptor in a Custom Binding Topology
Mravic, M.; He, L.; Kratochvil, H.; Hu, H.; Nick, S. E.; Bai, W.; Edwards, A.; Jo, H.; Wu, Y.; DiMaio, D.; DeGrado, W. F.
10.1101/2023.02.13.526773 — bioengineering — Posted on 2023-02-15
1957 High-fidelity Database-free Deep Learning Reconstruction for Real-time Cine Cardiac MRI
Demirel, O. B.; Zhang, C.; Yaman, B.; Gulle, M.; Shenoy, C.; Leiner, T.; Kellman, P.; Akcakaya, M.
10.1101/2023.02.13.528388 — bioengineering — Posted on 2023-02-15
1958 Structural Optimization of siRNA Conjugates for Albumin Binding Achieves Effective MCL1-Targeted Cancer Therapy
Hoogenboezem, E.; Patel, S. S.; Cavnar, A.; Lo, J.; Babb, L.; Francini, N.; Patil, P.; Colazo, J.; Michell, D. L.; Sanchez, V.; McCune, J.; Ma, J.; DeJulius, C.; Lee, L.; Rosch, J.; Allen, R.; Stokes, L.; Hill, J.; Vickers, K.; Cook, R.; Duvall, C.
10.1101/2023.02.14.528574 — bioengineering — Posted on 2023-02-15
1959 A dynamic inflammation model for neutrophil and monocyte responses in sepsis, trauma and surgery patient clusters.
Browning, B.; Couenne, F.; Bordes, C.; Fayolle, L.; Venet, F.; Textoris, J.; monneret, g.; Tayakout, M.
10.1101/2023.02.14.527104 — bioengineering — Posted on 2023-02-15
1960 An epigenetic clock in an insect model system
Brink, K.; Thomas, C.; Jones, A.; Mallon, E. B.
10.1101/2023.02.14.528436 — genomics — Posted on 2023-02-15
1968 Haptoglobin buffers lipopolysaccharides to safeguard against aberrant NFκB activation
Zein, L.; Grossmann, J.; Swoboda, H.; Borgel, C.; Wilke, B.; Awe, S.; Nist, A.; Stiewe, T.; Stehling, O.; Freibert, S.-A.; Adhikary, T.; Chung, H.-R.
10.1101/2022.11.22.516855 — immunology — Posted on 2023-02-15
1971 Perinuclear damage from nuclear envelope deterioration elicits stress responses that contribute to LMNA cardiomyopathy
Sikder, K.; Phillips, E.; Zhong, Z.; Wang, N.; Saunders, J.; Mothy, D.; Kossenkov, A.; Schneider, T.; Nichtova, Z.; Csordas, G.; Margulies, K. B.; Choi, J. C.
10.1101/2023.02.14.528563 — cell biology — Posted on 2023-02-14
1974 In vivo evaluation of the effect of sickle cell hemoglobin S, C and therapeutic transfusion on erythrocyte metabolism and cardiorenal dysfunction
D'Alessandro, A.; Nouraie, M.; Zhang, Y.; Cendali, F.; Gamboni, F.; Reisz, J. A.; Zhang, X.; Bartsch, K. W.; Galbraith, M. D.; Gordeuk, V. R.; Gladwin, M. T.
10.1101/2023.02.13.528368 — biochemistry — Posted on 2023-02-14
1976 Metformin impairs trophoblast metabolism and differentiation in dose dependent manner
Nashif, S. K.; Mahr, R. M.; Jena, S.; Jo, S.; Nelson, A. B.; Sadowski, D.; Crawford, P. A.; Puchalska, P.; Alejandro, E. U.; Gearhart, M. D.; Wernimont, S. A.
10.1101/2023.02.14.528531 — cell biology — Posted on 2023-02-14
1977 Physiological reprogramming in vivo mediated by Sox4 pioneer factor activity
Katsuda, T.; Sussman, J.; Ito, K.; Katznelson, A.; Yuan, S.; Li, J.; Merrell, A. J.; Takenaka, N.; Cure, H.; Li, Q.; Rasool, R. U.; Asangani, I. A.; Zaret, K. S.; Stanger, B.
10.1101/2023.02.14.528556 — cell biology — Posted on 2023-02-14
1978 Translatome analysis reveals microglia and astrocytes to be distinct regulators of inflammation in the hyperacute and acute phases after stroke
Buckwalter, M. S.; Hernandez, V. G.; Lechtenberg, K. J.; Peterson, T. C.; Zhu, L.; Lucas, T. A.; Owah, J. O.; Dorsey, A. I.
10.1101/2023.02.14.520351 — neuroscience — Posted on 2023-02-14
1980 AMLs harboring DNMT3A-destabilizing variants show increased intratumor DNA methylation heterogeneity at bivalent chromatin domains
Lee, D.; Koo, B.; Kim, S.-H.; Byun, J.; Hong, J.; Shin, D.-Y.; Sun, C.-H.; Song, J.-J.; Kim, J.; Jaiswal, S.; Yoon, S.-s.; Kim, S.; Koh, Y.
10.1101/2023.02.13.528223 — cancer biology — Posted on 2023-02-14
1982 A closer look at high-energy X-ray-induced bubble formation during soft tissue imaging
Xian, R. P.; Brunet, J.; Huang, Y.; Wagner, W. L.; Lee, P. D.; Tafforeau, P.; Walsh, C. L.
10.1101/2023.02.14.528474 — biochemistry — Posted on 2023-02-14
1983 Kinetics and efficacy of antibody drug conjugates in 3D tumour models
Chaundler, C. S. P.; Lu, H.; Fu, R.; Wang, N.; Lou, H.; Serrano de Almeida, G.; Hadi, L. M.; Aboagye, E.; Ghaem-Maghami, S.
10.1101/2023.02.14.528517 — biochemistry — Posted on 2023-02-14
1984 An intramolecular bivalent degrader glues an intrinsic BRD4-DCAF16 interaction
Hsia, O.; Hinterndorfer, M.; Cowan, A. D.; Iso, K.; Ishida, T.; Sundaramoorthy, R.; Nakasone, M. A.; Rukavina, A.; Husnjak, K.; Wegner, M.; Correa-Saez, A.; Craigon, C.; Maniaci, C.; Testa, A.; Kaulich, M.; Dikic, I.; Winter, G. E.; Ciulli, A.
10.1101/2023.02.14.528511 — biochemistry — Posted on 2023-02-14
1989 Maribacter halichondris sp. nov., isolated from the marine sponge Halichondria panicea
Steiner, L. X.; Wiese, J.; Rahn, T.; Borchert, E.; Slaby, B. M.; Hentschel, U.
10.1101/2023.02.14.528435 — microbiology — Posted on 2023-02-14
1992 Plastic Leachate Exposure Drives Antibiotic Resistance and Virulence in Marine Bacterial Communities
Vlaanderen, E. J.; Ghaly, T. M.; Moore, L. R.; Focardi, A.; Paulsen, I. T.; Tetu, S. G.
10.1101/2023.02.13.528379 — microbiology — Posted on 2023-02-14
1993 Structural landscape of the Respiratory Syncytial Virus nucleocapsids
Gonnin, L.; Desfosses, A.; Bacia-Verloop, M.; Chevret, D.; Galloux, M.; Eleouet, J.-F.; Gutsche, I.
10.1101/2023.02.14.528440 — microbiology — Posted on 2023-02-14
1994 Sarbecoviruses of British Horseshoe Bats; Sequence Variation and Epidemiology
Apaa, T.; Withers, A. J.; Staley, C. E.; Blanchard, A. M.; Bennett, M.; Bremner-Harrison, S.; Chadwick, E. A.; Hailer, F.; Harrison, S. W. R.; Loose, M.; Mathews, F.; Tarlinton, R. E.
10.1101/2023.02.14.528476 — microbiology — Posted on 2023-02-14
1997 Nearly (?) sterile avian egg in a passerine bird
Tesicky, M.; Schmiedova, L.; Krajzingrova, T.; Gomez Samblas, M.; Bauerova, P.; Kreisinger, J.; Vinkler, M.
10.1101/2023.02.14.528324 — microbiology — Posted on 2023-02-14
2001 Microglial CD68 and L-ferritin upregulation in response to phosphorylated-TDP-43 pathology in the amyotrophic lateral sclerosis brain
Swanson, M. E. V.; Mrkela, M.; Murray, H. C.; Cao, M. C.; Turner, C.; Curtis, M. A.; Faull, R. L. M.; Walker, A. K.; Scotter, E. L.
10.1101/2023.02.14.528561 — neuroscience — Posted on 2023-02-14
2002 Noradrenergic input from nucleus of the solitary tract regulates parabrachial activity in mice
Ji, Y.; Onwukwe, C.; Smith, J.; Laub, H.; Posa, L.; Keller, A.; Masri, R.; Cramer, N.
10.1101/2022.09.29.510103 — neuroscience — Posted on 2023-02-14
2004 Organic cation transporter 2 contributes to SSRI antidepressant efficacy by controlling tryptophan availability in the brain
Orrico-Sanchez, A.; Guiard, B.; Manta, S.; Callebert, J.; Launay, J.-M.; Louis, F.; Paccard, A.; Gruszczynski, C.; Betancur, C.; Vialou, V.; Gautron, S. L.
10.1101/2023.02.14.528444 — neuroscience — Posted on 2023-02-14
2006 Affinity-ranking BIN1 interactions and screening natural BIN1 variants that may cause neuromuscular disorders
Zambo, B.; Edelweiss, E.; Morlet, B.; Negroni, L.; Ostergaard, S.; Laporte, J.; Trave, G.; Gogl, G.
10.1101/2023.02.14.528471 — biochemistry — Posted on 2023-02-14
2009 Learning functional conservation between pig and human to decipher evolutionary mechanisms underlying gene expression and complex trait
Li, J.; Zhao, T.; Guan, D.; Pan, Z.; Bai, Z.; Teng, J.; Zhang, Z.; Zheng, Z.; Zeng, J.; Zhou, H.; Fang, L.; Cheng, H.
10.1101/2023.01.13.523857 — genetics — Posted on 2023-02-14
2011 Transcription regulation of SARS-CoV-2 receptor ACE2 by Sp1: a potential therapeutic target
Han, H.; Luo, R.-H.; Long, X.-Y.; Wang, L.-Q.; Zhu, Q.; Tang, X.-Y.; Zhu, R.; Ma, Y.-C.; Zheng, Y.-T.; Zou, C.-g.
10.1101/2023.02.14.528496 — microbiology — Posted on 2023-02-14
2012 Extra-islet expression of islet antigen boosts T-cell exhaustion to prevent autoimmune diabetes
Selck, C.; Jhala, G.; De George, D.; Kwong, C.-T. J.; Christensen, M. K.; Pappas, E.; Liu, X.; Ge, T.; Trivedi, P.; Kallies, A.; Thomas, H.; Kay, T. W. H.; Krishnamurthy, B.
10.1101/2023.02.12.528226 — immunology — Posted on 2023-02-14
2013 P-Selectin promotes SARS-CoV-2 interactions with platelets and the endothelium
Moreno, C. L.; Castanheira, F. V. S.; Stella, A. O.; Chung, F.; Aggarwal, A.; Cole, A. J.; Loo, L.; Dupuy, A.; Kong, Y.; Hagimola, L.; Fenwick, J.; Coleman, P.; Wilson, M.; Bui-Marinos, M.; Hesselson, D.; Gamble, J.; Passam, F.; Turville, S.; Kubes, P.; Neely, G. G.
10.1101/2023.02.13.528235 — immunology — Posted on 2023-02-14
2018 Whole-brain, gray and white matter time-locked functional signal changes with simple tasks and model-free analysis
Schilling, K.; Li, M.; Rheault, F.; Gao, Y.; Cai, L. Y.; Zhao, Y.; Xu, L.; Ding, Z.; Anderson, A. W.; Landman, B. A.; Gore, J. C.
10.1101/2023.02.14.528557 — neuroscience — Posted on 2023-02-14
2019 Cell-type-specific inhibitory circuitry from a connectomic census of mouse visual cortex
Schneider-Mizell, C. M.; Bodor, A.; Brittain, D.; Buchanan, J.; Bumbarger, D. J.; Elabbady, L.; Kapner, D.; Kinn, S.; Mahalingam, G.; Seshamani, S.; Suckow, S.; Takeno, M.; Torres, R.; Yin, W.; Dorkenwald, S.; Bae, J. A.; Castro, M. A.; Fahey, P. G.; Froudarakis, E.; Halageri, A.; Jia, Z.; Jordan, C.; Kemnitz, N.; Lee, K.; Li, K.; Lu, R.; Macrina, T.; Mitchell, E.; Mondal, S. S.; Mu, S.; Nehoran, B.; Papadopoulos, S.; Patel, S.; Pitkow, X.; Popovych, S.; Silversmith, W.; Sinz, F.; Turner, N. L.; Wong, W.; Wu, J.; Yu, S.-c.; MICrONs Consortium, ; Reimer, J.; Tolias, A.; Seung, H. S.; Reid, R.
10.1101/2023.01.23.525290 — neuroscience — Posted on 2023-02-14
2020 Metastatic potential in clonal melanoma cells is driven by a rare, early-invading subpopulation
Kaur, A.; Cuenca, L.; Kiani, K.; Busch, G.; Fingerman, D.; Dunagin, M. C.; Li, J.; Dardani, I.; Sanford, E. M.; Pemberton, J.; Goyal, Y.; Weeraratna, A. T.; Herlyn, M.; Raj, A.
10.1101/2022.04.17.488591 — cancer biology — Posted on 2023-02-14
2021 In vivo functional genomics identifies essentiality of potassium homeostasis in medulloblastoma
Fan, J. J.; Wang, X.; Erickson, A. W.; Skowron, P.; Wang, X.; Chen, X.; Shan, G.; Bahrampour, S.; Xiong, Y.; Dong, W.; Abeysundara, N.; Francisco, M. A.; Pusong, R. J.; Suarez, R. A.; Farooq, H.; Holgado, B. L.; Wu, X.; Daniels, C.; Dupuy, A. J.; Cadinanos, J.; Bradley, A.; Bagchi, A.; Moriarity, B. S.; Largaespada, D. A.; Morrissy, A. S.; Ramaswamy, V.; Mack, S. C.; Garzia, L.; Dirks, P. B.; Wanggou, S.; Li, X.; Sun, Y.; Taylor, M. D.; Huang, X.
10.1101/2022.07.23.501234 — cancer biology — Posted on 2023-02-14
2023 Comparative gene pathway analysis during adolescent binge-EtOH exposure, withdrawal, and following abstinence
Nato, A. Q.; Ata Ul Mustafa, H.; Sexton, H. G.; Moore, S. D.; Denvir, J.; Primerano, D. A.; Risher, M.-L.
10.1101/2020.11.02.365841 — bioinformatics — Posted on 2023-02-14
2024 Higher social tolerance is associated with more complex facial behavior in macaques
Rincon, A. V.; Waller, B. M.; Duboscq, J.; Mielke, A.; Perez, C.; Clark, P. R.; Micheletta, J.
10.1101/2022.12.07.519469 — animal behavior and cognition — Posted on 2023-02-14
2025 Insights into the diversity and function of DNA methyltransferases in microeukaryotes using the model diatom Phaeodactylum tricornutum
HOGUIN, A.; Yang, F.; Groisillier, A.; Bowler, C.; Genovesio, A.; Ait Mohamed, O.; Vieira, F. R.; TIRICHINE, L.
10.1101/2021.06.11.447926 — genomics — Posted on 2023-02-14
2029 Taste matters: Mapping expectancy-based appetitive placebo effects onto the brain
Khalid, I.; Rodrigues, B.; Dreyfus, H.; Frileux, S.; Meissner, K.; Fossati, P.; Hare, T. A.; Schmidt, L.
10.1101/2023.02.14.527858 — neuroscience — Posted on 2023-02-14
2030 Mapping Neurophysiological Subtypes of Major Depressive Disorder Using Normative Models of the Functional Connectome
Sun, X.; Liu, J.; Ma, Q.; Wang, X.; Wei, D.; Chen, Y.; Liu, B.; Huang, C.-C.; Zheng, Y.; Wu, Y.; Chen, T.; Cheng, Y.; Xu, X.; Gong, Q.; Si, T.; Qiu, S.; Lin, C.-P.; Cheng, J.; Tang, Y.; Wang, F.; Qiu, J.; Xie, P.; Li, L.; Wang, W.; He, Y.; DIDA-Major Depressive Disorder Working Group, ; Xia, M.
10.1101/2023.02.13.528399 — neuroscience — Posted on 2023-02-14
2031 2-photon imaging of fluorescent proteins in living swine
Costine-Bartell, B. A.; Martinez-Ramirez, L.; Normoyle, K. P.; Stinson, T. K.; Staley, K. J.; Lillis, K. P.
10.1101/2023.02.14.528533 — neuroscience — Posted on 2023-02-14
2034 A single-cell map of antisense oligonucleotide activity in the brain
Mortberg, M. A.; Gentile, J. E.; Nadaf, N.; Vanderburg, C.; Simmons, S.; Dubinsky, D.; Slamin, A.; Maldonado, S.; Petersen, C. L.; Jones, N.; Kordasiewicz, H. B.; Zhao, H. T.; Vallabh, S. M.; Minikel, E. V.
10.1101/2023.02.14.528473 — neuroscience — Posted on 2023-02-14
2035 Botrytis cinerea small RNAs are associated with tomato AGO1 and silence tomato defense-related target genes supporting cross-kingdom RNAi
He, B.; Cai, Q.; Weiberg, A.; Li, W.; Chen, A.-P.; Ouyang, S.; Borkovich, K.; Stajich, J.; Abreu-Goodger, C.; Jin, H.
10.1101/2022.12.30.522274 — plant biology — Posted on 2023-02-14
2036 Effects of a field-sprayed antibiotic on bee foraging behavior and pollination in pear orchards
Avila, L.; McCullough, C.; Schiffer, A.; Moreno, J.; Ganjur, N.; Ofenloch, Z.; DuPont, S. T.; Nottingham, L.; Gerardo, N. M.; Brosi, B. J.
10.1101/2023.02.14.528407 — animal behavior and cognition — Posted on 2023-02-14
2037 Measurement of Accumulation of Antibiotics to Staphylococcus aureus in Phagosomes
Dalesandro, B. E.; Kelly, J. J.; Liu, Z.; Chordia, M. D.; Ongwae, G. M.; Pires, M.
10.1101/2023.02.13.528196 — microbiology — Posted on 2023-02-14
2038 Neurexin 3 is required for the specific S-cone to S-cone bipolar cell synapse in the mammalian retina
Kunze, V. P.; Angueyra, J.; Ball, J. M.; Thomsen, M. B.; Li, X.; Sabnis, A.; Nadal-Nicolas, F. M.; Li, W.
10.1101/2023.02.13.527055 — neuroscience — Posted on 2023-02-14
2039 A Photoactivated Protein Degrader for Optical Control of Synaptic Function
Ko, T.; Jou, C.; Grau-Perales, A.; Reynders, M.; Fenton, A.; Trauner, D.
10.1101/2023.02.13.528397 — neuroscience — Posted on 2023-02-14
2041 A dynamic balance between neuronal death and clearance after acute brain injury
Balena, T.; Lillis, K.; Rahmati, N.; Bahari, F.; Dzhala, V.; Berdichevsky, Y.; Staley, K. J.
10.1101/2023.02.14.528332 — neuroscience — Posted on 2023-02-14
2042 Mitochondrial Pyruvate Carrier Inhibition in Hepatic Stellate Cells Attenuates Fibrosis in Nonalcoholic Steatohepatitis in Mice
Ferguson, D.; Habibi, M.; Eichler, S. J.; LaPoint, A.; Shew, T. M.; He, M.; Lutkewitte, A. J.; Finck, B. N.
10.1101/2023.02.13.528384 — physiology — Posted on 2023-02-14
2044 Selection of a Promiscuous Minimalist cAMP Phosphodiesterase from a Library of De Novo Designed Proteins
Schnettler Fernandez, D.; Wang, M. S.; Gantz, M.; Karas, C. E.; Hecht, M.; Hollfelder, F.
10.1101/2023.02.13.528392 — biochemistry — Posted on 2023-02-14
2046 Environmental context, parameter sensitivity and structural sensitivity impact predictions of annual-plant coexistence
Cervantes-Loreto, A.; Pastore, A. I.; Brown, C. R.; Marraffini, M. L.; Aldebert, C.; Mayfield, M. M.; Stouffer, D. B.
10.1101/2023.02.13.528375 — ecology — Posted on 2023-02-14
2047 Secreted long non-coding RNAs Gadlor1 and Gadlor2 aggravate cardiac remodelling during pressure overload by affecting multiple cardiac cell types
Keles, M.; Grein, S.; Froese, N.; Wirth, D.; Trogisch, F. A.; Wardman, R.; Hemanna, S.; Weinzierl, N.; Reiners-Koch, P.-S.; Uhlig, S.; Lomada, S.; Dittrich, G. M.; Szaroszyk, M.; Haustein, R.; Hegermann, J.; Martin Garrido, A.; Bauersachs, J.; Frank, D.; Frey, N.; Bieback, K.; Cordero, J.; Dobreva, G.; Wieland, T.; Heineke, J.
10.1101/2022.09.19.508486 — systems biology — Posted on 2023-02-14
2048 Propylene glycol inactivates respiratory viruses and prevents airborne transmission
Styles, C. T.; Zhou, J.; Flight, K. E.; Brown, J. C.; Vanden Oever, M.; Peacock, T. P.; Wang, Z.; Millns, R.; O'Neill, J. S.; Barclay, W. S.; Tregoning, J. S.; Edgar, R. S.
10.1101/2023.02.13.528349 — microbiology — Posted on 2023-02-14
2049 T-toxin virulence genes: unconnected dots in a sea of repeats
Haridas, S.; Gonzalez, J. B.; Riley, R.; Koriabine, M.; Yan, M.; Ng, V.; Rightmyer, A.; Grigoriev, I.; Baker, S. E.; Turgeon, B. G.
10.1101/2023.02.06.527415 — genomics — Posted on 2023-02-14
2051 Dual oxic-anoxic co-culture enables direct study of host-anaerobe interactions at the airway epithelial interface
Moore, P. J.; Wiggen, T. D.; Kent, L. A.; Arif, S. J.; Lucas, S. K.; Fletcher, J. R.; Villareal, A. R.; Gilbertsen, A. R.; O'Grady, S. M.; Hunter, R. C.
10.1101/2021.03.05.433759 — microbiology — Posted on 2023-02-14
2052 SARS-CoV-2 Neutralizing Antibodies After Bivalent vs. Monovalent Booster
Wang, Q.; Bowen, A. D.; Tam, A. R.; Valdez, R.; Stoneman, E.; Mellis, I. A.; Gordon, A.; Liu, L.; Ho, D. D.
10.1101/2023.02.13.528341 — microbiology — Posted on 2023-02-14
2054 Higher social tolerance is associated with more complex facial behavior in macaques
Rincon, A. V.; Waller, B. M.; Duboscq, J.; Mielke, A.; Perez, C.; Clark, P. R.; Micheletta, J.
10.1101/2022.12.07.519469 — animal behavior and cognition — Posted on 2023-02-14
2055 Distinct Wolbachia localization patterns in oocytes of diverse host species reveal multiple strategies of maternal transmission
Radousky, Y. A.; Hague, M. T. J.; Fowler, S.; Paneru, E.; Codina, A.; Rugamas, C.; Hartzog, G.; Cooper, B. S.; Sullivan, W.
10.1101/2022.10.28.514302 — cell biology — Posted on 2023-02-14
2056 Thermal Stimulus Task fMRI in the Cervical Spinal Cord at 7 Tesla
Seifert, A. C.; Xu, J.; Kong, Y.; Eippert, F.; Miller, K. L.; Tracey, I.; Vannesjo, S. J.
10.1101/2023.01.31.526451 — bioengineering — Posted on 2023-02-14
2057 The chromatin landscape of the euryarchaeon Haloferax volcanii
Marinov, G. K.; Bagdatli, S. T.; Wu, T.; He, C.; Kundaje, A.; Greenleaf, W.
10.1101/2022.07.22.501187 — genomics — Posted on 2023-02-14
2058 UBAP2L-dependent coupling of PLK1 localization and stability during mitosis
Guerber, L.; Vuidel, A.; Liao, Y.; Kleiss, C.; Grandgirard, E.; Sumara, I.; Pangou, E.
10.1101/2022.10.24.513562 — cell biology — Posted on 2023-02-14
2059 Subcytoplasmic location of translation controls protein output
Horste, E. L.; Zhen, G.; Fansler, M. M.; Chen, X.; Lee, F. C. Y.; Ule, J.; Mayr, C.
10.1101/2022.11.04.515216 — molecular biology — Posted on 2023-02-14
2060 No evidence that post-training D2R dopaminergic drug administration affects differential fear responding in rats
Schroyens, N.; Vercammen, L.; Ozcan, B.; Ossorio Salazar, V. A.; Zaman, J.; De Bundel, D.; Beckers, T.; Luyten, L.
10.1101/2022.02.02.478781 — neuroscience — Posted on 2023-02-14
2065 Working memory and imagery in early visual cortex
Weber, S.; Christophel, T.; Görgen, K.; Soch, J.; Haynes, J.-D.
10.1101/2023.02.13.528298 — neuroscience — Posted on 2023-02-14
2066 Rhythmic oscillations in the midbrain dopaminergic nuclei in mice
Oberto, V.; Matsumoto, J.; Pompili, M. N.; Todorova, R.; Papaleo, F.; Nishijo, H.; Venance, L.; Vandecasteele, M.; Wiener, S.
10.1101/2022.12.24.521864 — neuroscience — Posted on 2023-02-14
2067 Microcircuit failure in STXBP1 encephalopathy leads to hyperexcitability
Santos, A. B. d.; Larsen, S. D.; Guo, L.; Montalant, A.; Verhage, M.; Sorensen, J. B.; Perrier, J.-F.
10.1101/2023.02.14.528452 — neuroscience — Posted on 2023-02-14
2069 Motor "laziness" constrains fixation selection in real-world tasks
Burlingham, C. S.; Sendhilnathan, N.; Komogortsev, O.; Murdison, T. S.; Proulx, M. J.
10.1101/2023.02.13.528190 — neuroscience — Posted on 2023-02-14
2070 Adolescent Intermittent Ethanol Exposure Alters Exploratory and Affective Behaviors, and Cerebellar Grin2B Expression in Adulthood
Healey, K.; Waters, R. C.; Knight, S. G.; Wandling, G. M.; Hall, N. I.; Jones, B. N.; Shobande, M. J.; Melton, J. G.; Pandey, S. C.; Swartzwelder, H. S.; Maldonado-Devincci, A. M.
10.1101/2023.02.13.528396 — neuroscience — Posted on 2023-02-14
2071 Unraveling Chamber-specific Differences in Intercalated Disc Ultrastructure and Molecular Organization and Their Impact on Cardiac Conduction
Struckman, H. L.; Moise, N.; King, D. R.; Soltisz, A. M.; Buxton, A.; Dunlap, I.; Chen, Z.; Radwanski, P. B.; Weinberg, S. H.; Veeraraghavan, R.
10.1101/2023.02.13.528369 — physiology — Posted on 2023-02-14
2073 Optimizing Xenium In Situ data utility by quality assessment and best practice analysis workflows
Marco Salas, S.; Czarnewski, P.; Kuemmerle, L. B.; Helgadottir, S.; Mattsson Langseth, C.; Tiesmeyer, S.; Avenel, C.; Rehman, H.; Tiklova, K.; Andersson, A.; Chatzinikolaou, M. P.; Theis, F. J.; Luecken, M. D.; Wahlby, C.; Ishaque, N.; Nilsson, M.
10.1101/2023.02.13.528102 — bioinformatics — Posted on 2023-02-14
2074 Cell-type deconvolution of bulk RNA-Seq from kidney using opensource bioinformatic tools
Riojas, A.; Spradling-Reeves, K. D.; Christensen, C. L.; Hall-Ursone, S.; Cox, L. A.
10.1101/2023.02.13.528258 — genomics — Posted on 2023-02-14
2077 Developmental biomechanics and age polyethism in leaf-cutter ants
Pueffel, F.; Meyer, L.; Imirzian, N.; Roces, F.; Johnston, R. E.; Labonte, D.
10.1101/2023.02.13.528272 — developmental biology — Posted on 2023-02-14
2079 Histone variant H2B.Z acetylation is necessary for maintenance of Toxoplasma gondii biological fitness
Vanagas, L.; Munoz, D.; Cristaldi, C.; Ganuza, A.; Najera, R.; Bonardi, M. C.; Turowski, V. R.; Guzman, F.; Deng, B.; Kim, K.; Sullivan, W. J.; Angel, S. O.
10.1101/2023.02.14.528480 — cell biology — Posted on 2023-02-14
2083 High-gamma activity is coupled to low-gamma oscillations in precentral cortices and modulates with movement and speech
Nie, J. Z.; Flint, R.; Prakash, P.; Hsieh, J. K.; Mugler, E. M.; Tate, M. C.; Rosenow, J. M.; Slutzky, M. W.
10.1101/2023.02.13.528325 — neuroscience — Posted on 2023-02-14
2084 BOLD response is more than just magnitude: improving detection sensitivity through capturing hemodynamic profiles
Chen, G.; Taylor, P. A.; Reynolds, R. C.; Leibenluft, E.; Pine, D. S.; Brotman, M. A.; Pagliaccio, D.; Haller, S. P.
10.1101/2023.02.13.528362 — neuroscience — Posted on 2023-02-14
2085 Macrophage epigenetic memories of early life injury drive neonatal nociceptive priming
Dourson, A. J.; Fadaka, A. O.; Warshak, A. M.; Paranjpe, A.; Weinhaus, B.; Queme, L. F.; Hofmann, M. C.; Evans, H. M.; Donmez, O. A.; Forney, C.; Weirauch, M. T.; Kottyan, L. T.; Lucas, D.; Deepe, G. S.; Jankowski, M. P.
10.1101/2023.02.13.528015 — neuroscience — Posted on 2023-02-14
2088 Multilevel Omics-Readouts of in vitro Perturbation Studies are Determined by Memory Effects from Subculture
Bortel, P.; Hagn, G.; Skos, L.; Bileck, A.; Paulitschke, V.; Paulitschke, P.; Gleiter, L.; Mohr, T.; Gerner, C.; Meier-Menches, S.
10.1101/2023.02.13.528316 — systems biology — Posted on 2023-02-14
2089 Role of maternal, fetal and placental histopathology factors in the pathogenesis of retinopathy of prematurity.
Kaur, T.; Sharma, N.; Jakati, S.; Bagga, N.; Mitra, S.; Katamtreddy, B. K.; Jalali, S.; Kaur, I.
10.1101/2023.02.13.528236 — pathology — Posted on 2023-02-14
2090 A multi-omics integrative approach unravels novel genes and pathways associated with senescence escape after targeted therapy in NRAS mutant melanoma
Gureghian, V.; Herbst, H.; Kozar, I.; Mihajlovic, K.; Malod-Dognin, N.; Ceddia, G.; Angeli, C.; Margue, C.; Randic, T.; Philippidou, D.; Tetsi Nomigni, M.; Hemedan, A.; Tranchevent, L.-C.; Longworth, J.; Bauer, M.; Badkas, A.; Gaigneaux, A.; Muller, A.; ostaszewski, M.; Tolle, F.; Przulj, N.; Kreis, S.
10.1101/2023.02.13.528114 — cancer biology — Posted on 2023-02-14
2091 Non-specificity fingerprints for clinical stage antibodies in solution
Herling, T. W.; Invernizzi, G. I.; Ausserwoeger, H.; Bjelke, J. R.; Egebjerg, T.; Lund, S.; Lorenzen, N.; Knowles, T. P. J.
10.1101/2023.02.13.528263 — biophysics — Posted on 2023-02-14
2092 A comparison of bioinformatics pipelines for compositional analysis of the human gut microbiome
Szopinska-Tokov, J.; Bloemendaal, M.; Boekhorst, J.; Hermes, G. D.; Ederveen, T. H.; Vlaming, P.; Buitelaar, J. K.; Franke, B.; Arias-Vasquez, A.
10.1101/2023.02.13.528280 — bioinformatics — Posted on 2023-02-14
2097 In vivo evaluation of the effect of sickle cell hemoglobin S, C and therapeutic transfusion on erythrocyte metabolism and cardiorenal dysfunction
D'Alessandro, A.; Nouraie, M.; Zhang, Y.; Cendali, F.; Gamboni, F.; Reisz, J. A.; Zhang, X.; Bartsch, K. W.; Galbraith, M. D.; Gordeuk, V. R.; Gladwin, M. T.
10.1101/2023.02.13.528368 — biochemistry — Posted on 2023-02-14
2099 Multitrait diversification in marine diatoms in constant and warmed environments
Hinners, J.; Argyle, P. A.; Walworth, N. G.; Doblin, M. A.; Levine, N. M.; Collins, S.
10.1101/2022.04.08.487611 — evolutionary biology — Posted on 2023-02-14
2100 Predicting the antigenic evolution of SARS-COV-2 with deep learning
Han, W.; Chen, N.; Xu, X.; Sahil, A.; Zhou, J.; Li, Z.; Zhong, H.; Gao, E.; Zhang, R.; Wang, Y.; Sun, S.; Gao, X.; Cheung, P. P.-H.
10.1101/2022.06.23.497375 — evolutionary biology — Posted on 2023-02-14
2105 Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography
Wranik, M.; Weinert, T.; Slavov, C.; Masini, T.; Furrer, A.; Gaillard, N.; Gioia, D.; Ferrarotti, M.; James, D.; Glover, H.; Carrillo, M.; Kekilli, D.; Stipp, R.; Skopintsev, P.; Bruenle, S.; Muehlethaler, T.; Beale, J.; Gashi, D.; Nass, K.; Ozerov, D.; Johnson, P. J. M.; Cirelli, C.; Bacellar, C.; Braun, M.; Wang, M.; Dworkowski, F.; Milne, C.; Cavalli, A.; Wachtveitl, J.; Steinmetz, M.; Standfuss, J.
10.1101/2022.02.17.480857 — molecular biology — Posted on 2023-02-14
2107 Oscillatory brain activity as unified control mechanism for working memory and mentalizing
Friedrich, E. V. C.; Hilla, Y.; Sterner, E. F.; Ostermeier, S. S.; Behnke, L.; Sauseng, P.
10.1101/2023.02.13.528423 — neuroscience — Posted on 2023-02-14
2114 Nano-structured Hydrotrope-Caged Cytochrome c with Boosted Stability in Harsh Environments: A Molecular Insight
Bharadwaj, P.; Sarkar, D. K.; Bisht, M.; Shet, S. M.; Nataraj, S. K.; Lokesh, V.; Franklin, G.; Brezovsky, J.; Mondal, D.
10.1101/2023.02.05.527166 — biochemistry — Posted on 2023-02-14
2115 Coral settlement and recruitment are negatively related to reef fish trait diversity
Chow, C. F. Y.; Bolton, C.; Boutros, N.; Brambilla, V.; Fontoura, L.; Hoey, A. S.; Madin, J. S.; Pizarro, O.; Torres-Pulliza, D.; Woods, R. M.; Zawada, K. J. A.; Barbosa, M.; Dornelas, M.
10.1101/2021.10.19.464984 — ecology — Posted on 2023-02-14
2116 Comparative membrane proteomics reveals diverse cell regulators concentrated at the nuclear envelope
Cheng, L.-C.; Zhang, X.; Baboo, S.; Nguyen, J. A.; Martinez-Bartolome, S.; Loose, E.; Diedrich, J.; Yates, J. R.; Gerace, L.
10.1101/2023.02.13.528342 — cell biology — Posted on 2023-02-14
2118 Aerobic exercise reverses aging-induced depth-dependent decline in cerebral microcirculation
Shin, P.; Pian, Q.; Ishikawa, H.; Hamanaka, G.; Mandeville, E. T.; Shuzhen, G.; Buyin, F.; Alfadhel, M.; Allu, S. R.; Sencan-Egilmez, I.; Li, B.; Ran, C.; Vinogradov, S. A.; Ayata, C.; Lo, E.; Arai, K.; Devor, A.; Sakadzic, S.
10.1101/2023.02.12.528244 — neuroscience — Posted on 2023-02-14
2119 Judging the difficulty of perceptual decisions
Löffler, A.; Zylberberg, A.; N. Shadlen, M.; Wolpert, D. M.
10.1101/2023.02.13.528254 — neuroscience — Posted on 2023-02-14
2120 scAN1.0: A reproducible and standardized pipeline for processing 10X single cell RNAseq data
Lepetit, M.; Ilie, M. D.; Chanal, M.; Raverot, G.; Bertolino, P.; Arpin, C.; Picard, F.; Gandrillon, O.
10.1101/2022.11.07.515546 — bioinformatics — Posted on 2023-02-14
2122 Disruption of the Aspergillus fumigatus RNA interference machinery alters the conidial transcriptome.
Kelani, A. A.; Bruch, A.; Rivieccio, F.; Visser, C.; Krueger, T.; Weaver, D.; Pan, X.; Schaeuble, S.; Panagiotou, G.; Kniemeyer, O.; Bromley, M. J.; Bowyer, P.; Barber, A. E.; Brakhage, A. A.; Blango, M. G.
10.1101/2022.07.28.501871 — microbiology — Posted on 2023-02-14
2125 Inhibition of EV71 replication by an interferon-stimulated gene product L3HYPDH
Liu, J.; Liu, L.; Shinun Zeng, S.; Meng, X.; Lei, N.; Yang, H.; Li, R.; Mu, X.; Guo, X.
10.1101/304345 — microbiology — Posted on 2023-02-14
2131 Metabolic flux and flux balance analyses indicate the relevance of metabolic thermogenesis and aerobic glycolysis in cancer cells
Okahashi, N.; Shima, T.; Kondo, Y.; Araki, C.; Tsuji, S.; Sawai, A.; Uehara, H.; Kohno, S.; Shimizu, H.; Takahashi, C.; Matsuda, F.
10.1101/2021.11.16.468557 — cancer biology — Posted on 2023-02-14
2132 Q-SHINE: a versatile sensor for glutamine measurement via ligand-induced dimerization
Seo, M.-H.; Lim, Y.; Kim, J. Y.; Jung, Y. H.; Lee, J. H.; Baek, M. S.; Jung, J. H.; Kim, H.-Y.; Lee, W.; Park, K.
10.1101/2022.06.28.497868 — bioengineering — Posted on 2023-02-14
2136 Rab7 dependent regulation of goblet cell protein CLCA1 modulates gastrointestinal homeostasis
Gaur, P.; Rajendran, Y.; Srivastava, B.; Markandey, M.; Yoskovitz, V.-R.; Mohapatra, G.; Suhail, A.; Choudhary, S.; Tyagi, S.; Yadav, S. C.; Pandey, A. K.; Merbl, Y.; Bajaj, A.; Ahuja, V.; Srikanth, C.
10.1101/2023.02.13.528320 — cell biology — Posted on 2023-02-13
2137 The class XIV myosin of Toxoplasma gondii, TgMyoA, is druggable in an animal model of infection
Kelsen, A.; Kent, R. S.; Snyder, A. K.; Wehri, E.; Bishop, S. J.; Stadler, R. V.; Powell, C.; Martorelli di Genova, B.; Rompikuntal, P. K.; Boulanger, M. J.; Warshaw, D. M.; Westwood, N. J.; Schaletzky, J.; Ward, G. E.
10.1101/2022.09.09.507210 — microbiology — Posted on 2023-02-13
2138 Diversity and evolution of cerebellar folding in mammals
Heuer, K.; Traut, N.; de Sousa, A. A.; Valk, S.; Toro, R.
10.1101/2022.12.30.522292 — neuroscience — Posted on 2023-02-13
2140 Multi-omic network analysis identified betacellulin as a novel target of omega-3 fatty acid attenuation of western diet-induced nonalcoholic steatohepatitis.
Padiadpu, J.; Garcia-Jaramillo, M.; Newman, N.; Pederson, J.; Rodrigues, R.; Li, Z.; Singh, S.; Monnier, P.; Trinchieri, G.; Brown, K.; Dzutsev, A. K.; Shulzhenko, N.; Jump, D. B.; Morgun, A.
10.1101/2022.10.03.510635 — systems biology — Posted on 2023-02-13
2144 Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate in aging fibroblasts
Zhou, W.; Karan, K. R.; Klein, H.-U.; Sturm, G.; De Jager, P. L.; Bennett, D. A.; Hirano, M.; Picard, M.; Mills, R. E.
10.1101/2023.02.03.527065 — genomics — Posted on 2023-02-13
2145 Fgf signalling triggers an intrinsic mesodermal timer that determines the duration of limb patterning
Sedas Perez, S.; McQueen, C.; Pickering, J.; Chinnaiya, K.; Saiz-Lopez, P.; Ros, M. A.; Towers, M.
10.1101/2023.02.13.528267 — developmental biology — Posted on 2023-02-13
2147 Fixation Before Dissociation Using a Deep Eutectic Solvent Preserves In Vivo States and Phospho-Signaling in Single-Cell Sequencing
Fortmann, S. D.; Frey, B. F.; Hanumanthu, V. S.; Liu, S.; Goldsborough, A.; Kilchrist, K. V.; Ferrell, P. B.; Weaver, C. T.; Grant, M. B.; Welner, R. S.
10.1101/2023.02.13.528370 — immunology — Posted on 2023-02-13
2149 BHLHE40/41 regulate macrophage/microglia responses associated with Alzheimer's disease and other disorders of lipid-rich tissues
Podlesny-Drabiniok, A.; Novikova, G.; Liu, Y.; Dunst, J.; Temizer, R.; Giannarelli, C.; Marro, S.; Kreslavsky, T.; Marcora, E.; Goate, A. M.
10.1101/2023.02.13.528372 — neuroscience — Posted on 2023-02-13
2152 Cooperative super-enhancer inactivation caused by heterozygous loss of CREBBP and KMT2D skews B cell fate decisions and yields T cell-depleted lymphomas
Li, J.; Chin, C. R.; Ying, H.-Y.; Meydan, C.; Teater, M. R.; Xia, M.; Farinha, P.; Takata, K.; Chu, C.-S.; Rivas, M. A.; Chadburn, A.; Steidl, C.; Scott, D. W.; Roeder, R. G.; Mason, C. E.; Beguelin, W.; Melnick, A. M.
10.1101/2023.02.13.528351 — cancer biology — Posted on 2023-02-13
2157 Divergent patterns of meiotic double strand breaks and synapsis initiation dynamics suggest an evolutionary shift in the meiosis program between American and Australian marsupials
Valero-Regalon, F. J.; Sole, M.; Lopez-Jimenez, P.; Valerio-de Arana, M.; Martin-Ruiz, M.; de la Fuente, R.; Marin-Gual, L.; Renfree, M. B.; Shaw, G.; Berris, S.; Fernandez-Donoso, R.; Waters, P. D.; Ruiz-Herrera, A.; Gomez, R.; Page, J.
10.1101/2023.02.13.527877 — genetics — Posted on 2023-02-13
2158 Chromatin remodeling enzyme Snf2h is essential for retinal cell proliferation and photoreceptor maintenance
Kuzelova, A.; Dupacova, N.; Antosova, B.; Sunny, S. S.; Kozmik, Z.; Paces, J.; Skoultchi, A. I.; Stopka, T.; Kozmik, Z.
10.1101/2023.02.13.528323 — developmental biology — Posted on 2023-02-13
2159 Single cell transcriptomics identifies adipose tissue CD271+ progenitors for enhanced angiogenesis in limb ischemia
Inoue, O.; Goten, C.; Hashimuko, D.; Yamaguchi, K.; Takeda, Y.; Nomura, A.; Ootsuji, H.; Takashima, S.; Iino, K.; Takemura, H.; Halurkar, M.; Lim, H.-W.; Hwa, V.; Sanchez-Gurmaches, J.; Usui, S.; Takamura, M.
10.1101/2023.02.09.527726 — cell biology — Posted on 2023-02-13
2160 Ubiquitination is a novel post-translational modification of VMP1 in autophagy of human tumor cells
Renna, F. J.; Steinberg, J. H. E.; Manifava, M.; Gonzalez, C. D.; Tadic, M. S.; Orquera, T.; Vecino, C. V.; Ropolo, A.; Rossi, M.; Ktistakis, N. T.; Vaccaro, M. I.
10.1101/2023.02.13.528037 — cell biology — Posted on 2023-02-13
2161 Rapid in vitro activity of telavancin against Bacillus anthracis and in vivo protection against inhalation anthrax infection in the rabbit model
Lawrence, W. S.; Peel, J. E.; Slayden, R.; Peterson, J. W.; Baze, W. B.; Hensel, M. E.; Whorton, E. B.; Beasley, D. W.; Cummings, J. E.; Macias-Perez, I.
10.1101/2023.02.13.528259 — microbiology — Posted on 2023-02-13
2162 Exposure to Zika and chikungunya viruses impacts aspects of the vectorial capacity of Aedes aegypti and Culex quinquefasciatus
Crespo, M. M. C. C.; Guedes, D. R. D.; Paiva, M. H. S.; Sobral, M. C. d. M.; Helvecio, E.; da Silva, R. A.; Diniz, G. T. N.; Oliveira, C. M. F.; de Melo Santos, M. A. V.; Barbosa, R. M. R.; Ayres, C. F. J.
10.1101/2023.02.13.526953 — microbiology — Posted on 2023-02-13
2163 Repeated Plasmodium vivax blood stage infection provides sterile protection against homologous challenge in non-human primates
Obaldia, N.; da Silva Filho, J. L.; Nunez, M.; Glass, K.; Oulton, T.; Achcar, F.; Wirjanata, G.; Duraisingh, M.; Felgner, P.; Tetteh, K.; Bozdech, Z.; Otto, T.; Marti, M.
10.1101/2023.02.13.528262 — microbiology — Posted on 2023-02-13
2164 Chemokine positioning determines mutually exclusive roles for their receptors in extravasation of pathogenic human T cells
Parween, F.; Singh, S. P.; Zhang, H. H.; Kathuria, N.; Otaizo-Carrasquero, F. A.; Shamsaddini, A.; Gardina, P. J.; Ganesan, S.; Kabat, J.; Lorenzi, H. A.; Myers, T. G.; Farber, J. M.
10.1101/2023.01.25.525561 — immunology — Posted on 2023-02-13
2166 Single-cell transcriptomics of resected human traumatic brain injury tissues reveals acute activation of endogenous retroviruses in oligodendrocytes
Garza, R.; Sharma, Y.; Atacho, D.; Hamdeh, S. A.; Jonsson, M. E.; Horvath, V.; Ingelsson, M.; Jern, P.; Hammell, M. G.; Englund, E.; Jakobsson, J.; Marklund, N.
10.1101/2022.09.07.506982 — neuroscience — Posted on 2023-02-13
2167 Neuronal birthdate reveals topography in a vestibular brainstem circuit for gaze stabilization
Goldblatt, D.; Huang, S.; Greaney, M. R.; Hamling, K. R.; Voleti, V.; Perez-Campos, C.; Patel, K. B.; Li, W.; Hillman, E. M. C.; Bagnall, M. W.; Schoppik, D.
10.1101/2022.10.21.513243 — neuroscience — Posted on 2023-02-13
2171 Viral attachment blocking chimera composed of DNAorigami and nanobody inhibits Pseudorabies Virusinfection in vitro
Pradhan, S.; Swanson, C. J.; Leff, C.; Tengganu, I.; Bergeman, M.; Hogue, I. B.; Hariadi, R. F.
10.1101/2023.02.13.528373 — biophysics — Posted on 2023-02-13
2173 Hemodynamics in Patients with Aortic Coarctation: A Comparison of in vivo 4D-Flow MRI and FSI Simulation
Nair, P. J.; Pfaller, M. R.; Dual, S. A.; Loecher, M.; McElhinney, D. B.; Ennis, D. B.; Marsden, A. L.
10.1101/2023.02.13.528355 — bioengineering — Posted on 2023-02-13
2176 CK1δ homeostasis by activity-dependent shuttling and degradation of orphan kinase
Serrano, F. E.; Marzoll, D.; Ruppert, B.; Diernfellner, A. C. R.; Brunner, M.
10.1101/2023.02.13.528286 — biochemistry — Posted on 2023-02-13
2178 Amplification is the Primary Mode of Gene-by-Sex Interaction in Complex Human Traits
Zhu, C.; Ming, M. J.; Cole, J. M.; Edge, M. D.; Kirkpatrick, M.; Harpak, A.
10.1101/2022.05.06.490973 — genomics — Posted on 2023-02-13
2180 An allele-resolved nanopore-guided tour of the human placental methylome
Kindlova, M.; Byrne, H.; Kubler, J. M.; Steane, S. E.; Whyte, J. M.; Borg, D. J.; Clifton, V. L.; Ewing, A. D.
10.1101/2023.02.13.528289 — genomics — Posted on 2023-02-13
2181 Expansion of GTP cyclohydrolase I copy number in malaria parasites resistant to a pyrimidine biosynthesis inhibitor
Liu, S.; Ebel, E. R.; Kim, J.; Ene, N.; Braukmann, T. W. A.; Yeh, E.; Egan, E. S.; Guler, J. L.
10.1101/2023.02.13.528367 — genomics — Posted on 2023-02-13
2182 Functional convergence of genomic and transcriptomic genetic architecture underlying sociability in a live-bearing fish
Corral-Lopez, A.; Bloch, N. I.; van der Bijl, W.; Cortazar-Chinarro, M.; Szorkovszky, A.; Kotrschal, A.; Darolti, I.; Amcoff, M.; Buechel, S. D.; Romenskyy, M.; Kolm, N.; Mank, J. E.
10.1101/2023.02.13.528353 — evolutionary biology — Posted on 2023-02-13
2186 Pannexin 3 channels regulate architecture, adhesion, barrier function and inflammation in the skin
O'Donnell, B. L.; Sanchez-Pupo, R. E.; Sayedyahossein, S.; Karimi, M.; Bahmani, M.; Zhang, C.; Johnston, D.; Kelly, J.; Wakefield, C. B.; Barr, K.; Dagnino, L.; Penuela, S.
10.1101/2022.07.13.499920 — cell biology — Posted on 2023-02-13
2187 Loss of PTPMT1 limits mitochondrial utilization of carbohydrates and leads to muscle atrophy and heart failure
Zheng, H.; Li, Q.; Li, S.; Li, Z.; Brotto, M.; Weiss, D.; Prosdocimo, D.; Xu, C.; Reddy, A.; Puchowicz, M.; Zhao, X.; Weitzmann, M. N.; Jain, M. K.; Qu, C.-K.
10.1101/2023.01.09.523031 — cell biology — Posted on 2023-02-13
2190 Intracellular replication of Pseudomonas aeruginosa in epithelial cells requires suppression of the caspase-4 inflammasome
Kroken, A. R.; Klein, K. A.; Mitchell, P. S.; Nieto, V.; Jedel, E. J.; Evans, D. J.; Fleiszig, S. M. J.
10.1101/2023.02.13.528260 — microbiology — Posted on 2023-02-13
2191 Metabolic resource overlap impacts on the competition of phyllosphere bacteria
Schlechter, R. O.; Kear, E. J.; Bernach, M.; Remus, D. M.; Remus-Emsermann, M. N. P.
10.1101/2022.01.20.477054 — microbiology — Posted on 2023-02-13
2192 Lymphocyte activation gene 3 (Lag3) supports Foxp3+ Treg cell function by restraining c-Myc-dependent aerobic glycolysis
Kim, D.; Kim, G.; Yu, R.; Lee, J.; Kim, S.; Qiu, K.; Montauti, E.; Fang, D.; Chandel, N. S.; Choi, J.; Min, B.
10.1101/2023.02.13.528371 — immunology — Posted on 2023-02-13
2194 Evolution of connectivity architecture in the Drosophila mushroom body
Ellis, K. E.; Smihula, H.; Ganguly, I.; Vigato, E.; Bervoets, S.; Auer, T. O.; Benton, R.; Litwin Kumar, A.; Caron, S. J. C.
10.1101/2023.02.10.528036 — neuroscience — Posted on 2023-02-13
2197 Phosphoproteomics of cellular mechanosensing reveals NFATC4 as a regulator of myofibroblast activity
Mattner, L. F.; Zeng, Z.; Mayr, C. H.; Ansari, M.; Wei, X.; Asgharpour, S.; Kneidinger, N.; Stoleriu, G. M.; Behr, J.; Polleux, J.; Yildirim, A. O.; Burgstaller, G.; Mann, M.; Schiller, H. B.
10.1101/2023.02.13.528335 — systems biology — Posted on 2023-02-13
2199 HEXOKINASE 1 Control of Post-Germinative Seedling Growth
Lincoln, M. J.; Ganpudi, A.; Romanowski, A.; Halliday, K. J.
10.1101/548990 — plant biology — Posted on 2023-02-13
2200 A bench-top dark-root device built with LEGO bricks enables a non-invasive plant root development analysis in soil conditions mirroring nature
Dermendjiev, G.; Schnurer, M.; Stewart, E.; Naegele, T.; Marino, G.; Leister, D.; Thuer, A.; Plott, S.; Jez, J.; Ibl, V.
10.1101/2023.02.12.528178 — plant biology — Posted on 2023-02-13
2201 Light sensitive short hypocotyl (LSH) confer symbiotic nodule identity in the legume Medicago truncatula
Schiessl, K.; Lee, T.; Orvosova, M.; Bueno-Batista, M.; Stuer, N.; Bailey, P. C.; Wen, J.; Mysore, K.; Oldroyd, G. E.
10.1101/2023.02.12.528179 — plant biology — Posted on 2023-02-13
2203 A non-canonical Hippo pathway represses the expression of deltaNp63
Low-Calle, A. M.; Ghoneima, H.; Ortega, N.; Cuibus, A. M.; Katz, C.; Tong, D.; Prives, C.; Prywes, R.
10.1101/2023.02.13.528336 — cancer biology — Posted on 2023-02-13
2206 Mechanical Property Based Brain Age Prediction using Convolutional Neural Networks
Clements, R. G.; Claros-Olivares, C. C.; McIlvain, G.; Brockmeier, A. J.; Johnson, C. L.
10.1101/2023.02.12.528186 — bioengineering — Posted on 2023-02-13
2207 Crystal structures reveal the framework of cis-acyltransferase modular polyketide synthases
Keatinge-Clay, A. T.; Miyazawa, T.; Zhang, J.; Ray, K. A.; Lutgens, J. D.; Bista, R.; Lin, S. N.
10.1101/2023.02.11.528132 — biochemistry — Posted on 2023-02-13
2210 Distinct regulatory networks control toxin gene expression in elapid and viperid snakes
Modahl, C. M.; Han, X.; van Thiel, J.; Vaz, C.; Dunstan, N. L.; Frietze, S.; Jackson, T. N. W.; Mackessy, S. P.; Kini, R. M.
10.1101/2023.02.13.528252 — evolutionary biology — Posted on 2023-02-13
2211 Apical extrusion prevents apoptosis from activating an acute inflammatory program in epithelia.
Duszyc, K.; von Pein, J.; Ramnath, D.; Currin-Ross, D.; Verma, S.; Lim, F.; Sweet, M. J.; Schroder, K.; Yap, A. S.
10.1101/2023.02.12.528237 — cell biology — Posted on 2023-02-13
2215 A new genetic method for diet determination from faeces that provides species level resolution in the koala
Blyton, M. D. J.; Brice, K. L.; Heller-Uszynska, K.; Pascoe, J.; Jaccoud, D.; Leigh, K. A.; Moore, B. D.
10.1101/2023.02.12.528172 — microbiology — Posted on 2023-02-13
2216 Connectome architecture shapes large-scale cortical reorganization in schizophrenia: a worldwide ENIGMA study
Georgiadis, F.; Lariviere, S.; Glahn, D.; Hong, E.; Kochunov, P.; Mowry, B.; Loughland, C.; Pantelis, C.; Henskens, F.; Green, M.; Cairns, M.; Michie, P.; Rasser, P.; Tooney, P.; Scott, R.; Catts, S.; Schall, U.; Carr, V.; Quide, Y.; Krug, A.; Stein, F.; Nenadic, I.; Brosch, K.; Kircher, T.; Gur, R.; Gur, R.; Satterthwaite, T.; Karuk, A.; Clotet, E.; Radua, J.; Claramonte, P.; Salvador, R.; Spalletta, G.; Voineskos, A.; Sim, K.; Facorro, B.; Gutierrez, D.; Ehrlich, S.; Crossley, N.; Grotegerd, D.; Repple, J.; Lencer, R.; Dannlowski, U.; Calhoun, V.; Demro, C.; Ramsay, I.; Sponheim, S.; Schmidt
10.1101/2023.02.12.527904 — neuroscience — Posted on 2023-02-13
2220 The impact of patient-specific inlet conditions on oscillatory shear and helicity in haemodynamic simulations of aneurysmal Type-B Aortic Dissection
Stokes, C.; Ahmed, D.; Lind, N.; Haupt, F.; Becker, D.; Hamilton, J.; Muthurangu, V.; von Tengg-Kobligk, H.; Papadakis, G.; balabani, s.; Diaz, V.
10.1101/2023.02.12.528194 — bioengineering — Posted on 2023-02-13
2227 Integrative single-cell characterization of frugivory adaptations in the bat kidney and pancreas
Gordon, W. E.; Baek, S.; Nguyen, H. P.; Kuo, Y.-M.; Bradley, R.; Galazyuk, A.; Lee, I.; Ingala, M.; Simmons, N. B.; Schountz, T.; Cooper, L.; Georgakopoulos-Soares, I.; Hemberg, M.; Ahituv, N.
10.1101/2023.02.12.528204 — genomics — Posted on 2023-02-13
2230 Taurine as a key intermediate for host-symbiont interaction in the tropical sponge Ianthella basta
Moeller, F. U.; Herbold, C. W.; Schintlmeister, A.; Mooshammer, M.; Motti, C.; Behnam, F.; Watzka, M.; Schweder, T.; Albertsen, M.; Richter, A.; Webster, N. S.; Wagner, M.
10.1101/2022.09.23.509140 — microbiology — Posted on 2023-02-13
2231 Polyether ionophore antibiotics target drug-resistant clinical isolates, persister cells, and biofilms
Wollesen, M.; Mikkelsen, K.; Tvilum, M. S.; Vestergaard, M.; Wang, M.; Ingmer, H.; Meyer, R. L.; Poulsen, T. B.; Torring, T.
10.1101/2023.02.13.528344 — microbiology — Posted on 2023-02-13
2232 A comparative study of low-pH tolerance and chitinase activity between toxigenic and non-toxigenic strains of Vibrio cholerae
Jayaraman, V.; Khan, S. A.; Perinbam, K.; Rakheja, I.; Vadakkepat, A. K.; Chaudhary, S. K.; Pandey, A. K.; Mitra, J.
10.1101/2023.02.13.528346 — microbiology — Posted on 2023-02-13
2233 Extra-islet expression of islet antigen boosts T-cell exhaustion to prevent autoimmune diabetes
Selck, C.; Jhala, G.; De George, D.; Kwong, C.-T. J.; Christensen, M. K.; Pappas, E.; Liu, X.; Ge, T.; Trivedi, P.; Kallies, A.; Thomas, H.; Kay, T. W. H.; Krishnamurthy, B.
10.1101/2023.02.12.528226 — immunology — Posted on 2023-02-13
2235 rtPA Directly Protects Neurons After Intracerebral Hemorrhage through PI3K/AKT/mTOR Pathway
Jing, J.; Chen, S.; Wu, X.; Yang, J.; Liu, X.; Wang, J.; Wang, J.; Li, Y.; Zhang, P.; Tang, Z.
10.1101/2023.02.13.528249 — neuroscience — Posted on 2023-02-13
2238 HIV Pharmacology Data Repository (PDR): Setting the New Information Sharing Standard for Pharmacokinetic Studies
Tompkins, L. A. R.; Kapeljushnik, O.; Hubal, R.; Khoei, A.; Dumond, J.; Kashuba, A. D.; Tropsha, A.; Cottrell, M. L.
10.1101/2023.02.13.528350 — pharmacology and toxicology — Posted on 2023-02-13
2239 Quantitative Annotations of T-Cell Repertoire Specificity
Luo, J.; Wang, X.; Zou, Y.; Chen, L.; Liu, W.; Zhang, W.; Li, S.
10.1101/2023.01.29.526145 — bioinformatics — Posted on 2023-02-13
2241 Crystal ribcage: a platform for probing real-time lung function at cellular resolution in health and disease
Banerji, R.; Grifno, G. N.; Shi, L.; Smolen, D.; LeBourdais, R.; Muhvich, J.; Eberman, C.; Hiller, B.; Lee, J.; Regan, K.; Zheng, S.; Zhang, S. S.; Jiang, J.; Breda, J. C.; Pihl, R.; Traber, K.; Mazzilli, S.; Ligresti, G.; Mizgerd, J. P.; Suki, B.; Nia, H. T.
10.1101/2022.10.28.514251 — bioengineering — Posted on 2023-02-13
2244 Human neutrophils communicate remotely via glutamate-induced glutamate release
Kopach, O.; Sylantyev, S.; Bard, L.; Michaluk, P.; Gutierrez del Arroyo, A.; Ackland, G. L.; Rusakov, D. A.
10.1101/2022.02.25.482046 — cell biology — Posted on 2023-02-13
2245 Perforin-2 is a pore-forming effector of endocytic escape in cross- presenting dendritic cells
Rodriguez-Silvestre, P.; Laub, M.; Davies, A. K.; Schessner, J. P.; Krawczyk, P. A.; Tuck, B. J.; McEwan, W. A.; Borner, G. H. H.; Kozik, P.
10.1101/2023.01.31.525875 — cell biology — Posted on 2023-02-13
2248 Single cell transcriptomic analysis of renal allograft rejection reveals novel insights into intragraft TCR clonality
Shi, T.; Burg, A. R.; Caldwell, J. T.; Roskin, K.; Rojas, C. M. C.; Chukwuma, P. C.; Gray, G. I.; Foote, S. G.; Alonso, J.; Cuda, C. M.; Allman, D. A.; Rush, J. S.; Regnier, C. H.; Wieczorek, G.; Alloway, R. R.; Shields, A. R.; Baker, B. M.; Woodle, E. S.; Hildeman, D. A.
10.1101/2023.02.08.524808 — immunology — Posted on 2023-02-13
2249 Exploring the Connection between Autophagy and Heat-Stress Tolerance in Drosophila melanogaster
Willot, Q.; du Toit, A.; de Wet, S.; Huisamen, E. J.; Loos, B.; Terblanche, J. S.
10.1101/2021.12.09.471892 — physiology — Posted on 2023-02-13
2255 New algorithm for pearl millet modelling in APSIM allowing a mechanistic simulation of tillers
Garin, V.; Van Oosterom, E.; McLean, G.; Hammer, G.; Murugesan, T.; Kaliamoorthy, S.; Diancumba, M.; Hajjarpoor, A.; Kholova, J.
10.1101/2023.02.12.528159 — plant biology — Posted on 2023-02-13
2256 Optimization of chickpea irrigation in a semi-arid climate based on morpho-physiological parameters
Avneri, A.; Peleg, Z.; Bonfil, D.; Sadeh, R.; Perach, O.; Herrmann, I.; Abbo, S.; Lati, R.
10.1101/2023.02.12.528176 — plant biology — Posted on 2023-02-13
2257 Olivar: fully automated and variant aware primer design for multiplex tiled amplicon sequencing of pathogen genomes
Wang, M. X.; Lou, E. G.; Sapoval, N.; Kim, E.; Kalvapalle, P.; Kille, B.; Elworth, R. A. L.; Liu, Y.; Fu, Y.; Stadler, L. B.; Treangen, T. J.
10.1101/2023.02.11.528155 — bioinformatics — Posted on 2023-02-13
2260 Genomic, genetic and phylogenetic evidence for a new falcon species using chromosome-level genome assembly of the gyrfalcon and population genomics
Al-Ajli, F. O.; Formenti, G.; Fedrigo, O.; Tracey, A.; Sims, Y.; Howe, K.; Karkhi, I.; Althani, A.; Jarvis, E.; Rahman, S.; Ayub, Q.
10.1101/2023.02.12.525808 — genomics — Posted on 2023-02-13
2262 Proteolytic cleavage and inactivation of the TRMT1 tRNA modification enzyme by SARS-CoV-2 main protease
Zhang, K.; Ciesla, J. H.; Eldin, P.; Briant, L.; Lentini, J. M.; Ramos, J.; Munger, J.; Fu, D.
10.1101/2023.02.10.527147 — molecular biology — Posted on 2023-02-13
2263 Nuclear export inhibitor Selinexor targeting XPO1 enhances coronavirus replication.
Rahman, M. M.; Estifanos, B.; Glenn, H. L.; Kibler, K. V.; Li, Y.; Jacobs, B. L.; McFadden, G.; Hogue, B. G.
10.1101/2023.02.09.527884 — microbiology — Posted on 2023-02-13
2264 Regulatory T Cell-like Response to SARS-CoV-2 in Jamaican Fruit Bats Transduced with Human ACE2
Burke, B.; Rocha, S.; Zhan, S.; Eckley, M.; Reasoner, C.; Addetia, A.; Lewis, J.; Fagre, A. C.; Charley, P.; Richt, J. A.; Weiss, S. R.; Tjalkens, R.; Veesler, D.; Aboellail, T.; Schountz, T.
10.1101/2023.02.13.528205 — microbiology — Posted on 2023-02-13
2265 The disordered N-terminal tail of SARS CoV-2 Nucleocapsid protein forms a dynamic complex with RNA
Cubuk, J.; Alston, J. J.; Incicco, J. J.; Holehouse, A. S.; Hall, K. B.; Stuchell-Brereton, M. D.; Soranno, A.
10.1101/2023.02.10.527914 — biophysics — Posted on 2023-02-13
2267 Dopaminergic signals for reward, performance and social outcomes are dynamically gated during courtship
Roeser, A. C.; Gadagkar, V.; Das, A.; Puzerey, P. A.; Kardon, B. M.; Goldberg, J. H.
10.1101/822817 — neuroscience — Posted on 2023-02-13
2268 Evolutionary conserved and divergent responses to copper zinc superoxide dismutase inhibition in plants
Frohn, S.; Haas, F. B.; Dreyer, B.; Reiss, E.; Ziplys, A.; Weichert, H.; Chavez, B. G.; D'Auria, J. C.; Rensing, S. A.; Schippers, J.
10.1101/2023.02.11.528141 — plant biology — Posted on 2023-02-13
2269 Petagraph: A large-scale unifying knowledge graph framework for integrating biomolecular and biomedical data
Stear, B. J.; Ahooyi, T. M.; Vasisht, S.; Simmons, A.; Beigel, K.; Callahan, T. J.; Silverstein, J. C.; Taylor, D. M.
10.1101/2023.02.11.528088 — bioinformatics — Posted on 2023-02-13
2271 A resurrection ecology test for the effects of ionizing radiation and other environmental correlates on Daphnia evolution
Neely-Streit, T.; O'Toole, M.; Ciolak, E. M.; Islam, M.; Heathcote, A. J.; Masterson, A. L.; Walsh, M. R.; Stuart, Y. E.
10.1101/2023.02.10.524566 — evolutionary biology — Posted on 2023-02-13
2272 Selection on many loci drove the origin and spread of a key innovation
Stankowski, S.; Zagrodzka, Z. B.; Garlovsky, M. D.; Pal, A.; Shipilina, D.; Garcia Castillo, D. F.; Le Moan, A.; Leder, E.; Reeve, J.; Johannesson, K.; Westram, A.; Butlin, R. K.
10.1101/2023.02.13.528213 — evolutionary biology — Posted on 2023-02-13
2275 Complementary effects of above- and belowground biodiversity on ecosystem functions across global grasslands
S. C. Martins, C.; Delgado-Baquerizo, M.; Jayaramaiah, R. H.; Wang, J.-T.; Saez-Sandino, T.; Liu, H.; T. Maestre, F.; B. Reich, P.; Singh, B. K.
10.1101/2023.02.10.528097 — ecology — Posted on 2023-02-13
2277 Impact of aging on the immunological and microbial landscape of the lung during non-tuberculous mycobacterial infection
Cinco, I. R.; Rhoades, N. S.; Napier, E. G.; Davies, M.; Allison, D. B.; Kohama, S. G.; Bermudez, L. E.; Winthrop, K.; Fuss, C.; Spindel, E. R.; Messaoudi, I.
10.1101/2023.02.11.528140 — immunology — Posted on 2023-02-13
2285 The Small GTPase Rab7 Regulates Release of Mitochondria in Extracellular Vesicles in Response to Lysosomal Dysfunction
Liang, W.; Diao, R.; Quiles, J.; Najor, R.; Chi, L.; Woodall, B.; Leon, L.; Duran, J.; Cauvi, D.; De Maio, A.; Adler, E.; Gustafsson, A. B.
10.1101/2023.02.11.528148 — physiology — Posted on 2023-02-13
2286 Benchmarking robust spatial transcriptomics approaches to capture the molecular landscape and pathological architecture of archived cancer tissues
Vo, T.; Jones, K.; Yoon, S.; Lam, P. Y.; Kao, Y.-C.; Zhou, C.; Prakrithi, P.; Crawford, J.; Walters, S.; Gupta, I.; Soyer, H. P.; Khosrotehrani, K.; Stark, M. S.; Nguyen, Q.
10.1101/2023.02.11.527941 — pathology — Posted on 2023-02-13
2287 Deep spatial-omics to aid personalization of precision medicine in metastatic recurrent Head & Neck Cancers
Causer, A.; Tan, X.; Lu, X.; Moseley, P.; Teoh, M.; McGrath, M.; Kim, T.; Simpson, P.; Perry, C.; Frazer, I.; Panizza, B.; Ladwa, R.; Nguyen, Q.; Gonzalez Cruz, J. L.
10.1101/2023.02.10.527955 — cancer biology — Posted on 2023-02-13
2288 Life history and cancer in birds: clutch size predicts cancer
Kapsetaki, S. E.; Compton, Z.; Dolan, J.; Harris, V. K.; Rupp, S. M.; Duke, E. G.; Harrison, T. M.; Aksoy, S.; Giraudeau, M.; Vincze, O.; McGraw, K. J.; Aktipis, A.; Tollis, M.; Boddy, A. M.; Maley, C. C.
10.1101/2023.02.11.528100 — cancer biology — Posted on 2023-02-13
2290 Spatial omics imaging of fresh-frozen tissue and routine FFPE histopathology on a single cancer needle core biopsy: freezing device and multimodal workflow
Rittel, M. F.; Schmidt, S.; Weis, C.-A.; Birgin, E.; van Marwick, B.; Raedle, M.; Diehl, S.; Rahbari, N.; Marx, A.; Hopf, C.
10.1101/2023.02.11.528125 — cancer biology — Posted on 2023-02-13
2291 Breast Density Analysis of Digital Breast Tomosynthesis
Heine, J.; Fowler, E. E. E.; Weinfurtner, R. J.; Tworoger, S.; Hume, E.
10.1101/2023.02.10.527911 — biophysics — Posted on 2023-02-13
2293 Reply to: Caution Regarding the Specificities of Pan-Cancer Microbial Structure
Sepich-Poore, G. D.; Kopylova, E.; Zhu, Q.; Carpenter, C.; Fraraccio, S.; Wandro, S.; Kosciolek, T.; Janssen, S.; Metcalf, J.; Song, S. J.; Kanbar, J.; Miller-Montgomery, S.; Heaton, R.; Mckay, R.; Patel, S. P.; Swafford, A. D.; Knight, R.
10.1101/2023.02.10.528049 — bioinformatics — Posted on 2023-02-13
2295 Streamline unsupervised machine learning to survey and graph indel-based haplotypes from pan-genomes
Zhang, B.; Huang, H.; Tibbs-Cortes, L. E.; Vanous, A.; Zhang, Z.; Sanguinet, K.; Garland-Campbell, K. A.; Yu, J.; Li, X.
10.1101/2023.02.11.527743 — bioinformatics — Posted on 2023-02-13
2297 Genomic Resources for Asian (Elephas maximus) and African Savannah Elephant (Loxodonta africana) Conservation and Health Research
Prado, N. A.; Armstrong, E. E.; Brown, J. L.; Goldenberg, S. Z.; Leimgruber, P.; Pearson, V. R.; Maldonado, J. E.; Campana, M. G.
10.1101/2023.02.10.528067 — genomics — Posted on 2023-02-13
2298 The Crown Pearl V2: an improved genome assembly of the European freshwater pearl mussel Margaritifera margaritifera (Linnaeus, 1758)
Gomes-dos-Santos, A.; Lopes-Lima, M.; Machado, A. M.; Forest, T.; Achaz, G.; Teixeira, A.; Prie, V.; C. Castro, L. F.; Froufe, E.
10.1101/2023.02.11.528107 — genomics — Posted on 2023-02-13
2300 How useful is genomic data for predicting maladaptation to future climate?
Lind, B. M.; Candido-Ribeiro, R.; Singh, P.; Lu, M.; Obreht Vidakovic, D.; Booker, T. R.; Whitlock, M. C.; Yeaman, S.; Isabel, N.; Aitken, S. N.
10.1101/2023.02.10.528022 — evolutionary biology — Posted on 2023-02-13
2303 Cell population growth as manifestation of stochastic heterogeneity of cell phenotype
Wang, Y.; Zhou, J. X.; Pedrini, E.; Rubin, I.; Khalil, M.; Qian, H.; Huang, S.
10.1101/2023.02.08.527773 — cancer biology — Posted on 2023-02-13
2307 Direct Force Measurement and Loading on Developing Tissues in Intact Avian Embryos
Chan, C. U.; Xiong, F.; Michaut, A.; Vidigueira, J. M. N.; Pourquie, O.; Mahadevan, L.
10.1101/2022.06.20.496880 — developmental biology — Posted on 2023-02-13
2309 Predictive coding during action observation revealed by human electrocorticographic activity
Qin, C.; Michon, F.; Onuki, Y.; Ishishita, Y.; Otani, K.; Kawai, K.; Fries, P.; Gazzola, V.; Keysers, C.
10.1101/2022.12.13.519734 — neuroscience — Posted on 2023-02-13
2311 Stabilisation of β-Catenin-WNT signalling by USP10 in APC-truncated colorectal cancer drives cancer stemness and enables super-competitor signalling
Reissland, M.; Hartmann, O.; Tauch, S.; Prieto-Garcia, C.; Schulte, C.; Solvie, D.; Loebbert, S.; Jacomin, A. C.; Pesic, M.; Bugter, J. M.; Schuelein-Voelk, C.; Fuss, C.; Pahor, N.; Ade, C.; Buck, V.; Potente, M.; Li, V.; Beliu, G.; Wiegering, A.; Bitman-Lotan, E.; Grossmann, T.; Rosenfeldt, M.; Eilers, M.; Maric, H.; Maurice, M. M.; Greten, F.; Dikic, I.; Orian, A.; Gallant, P.; Diefenbacher, M. E.
10.1101/2023.02.10.527983 — cancer biology — Posted on 2023-02-13
2312 GENIUS: GEnome traNsformatIon and spatial representation of mUltiomicS data
Sokac, M.; Dyrskjot Andersen, L.; Haibe-Kains, B.; Aerts, H. J. W. L.; Birkbak, N. J.
10.1101/2023.02.09.525144 — bioinformatics — Posted on 2023-02-13
2313 GATA1 knockout in human pluripotent stem cells generates enhanced neutrophils to investigate extracellular trap formation
Harper, T. C.; Oberlick, E. M.; Smith, T. J.; Nunes, D. E.; Bray, M. A.; Park, S.; Driscoll, C. D.; Mowbray, S. F.; Antczak, C.
10.1101/2023.02.08.526339 — immunology — Posted on 2023-02-13
2314 CaV3.1 Channels Facilitate Calcium Wave Generation and Myogenic Tone Development in Mouse Mesenteric Arteries.
El-Lakany, M. A.; Haghbin, N.; Arora, N.; Hashad, A. M.; Mironova, G. Y.; Sancho, M.; Welsh, D. G.
10.1101/2023.02.10.528095 — systems biology — Posted on 2023-02-13
2315 Coronary Artery Disease risk variant dampens the expression of CALCRL by reducing HSF binding to shear stress responsive enhancer in endothelial cells
Selvarajan, I.; Li, J.; Pölönen, P.; Örd, T.; Öunap, K.; Ravindran, A.; Mäklin, K.; Toropainen, A.; Stolze, L.; White, S. J.; Romanoski, C. E.; Heinäniemi, M.; Fang, Y.; Kaikkonen, M. U.
10.1101/2023.02.08.527795 — genetics — Posted on 2023-02-13
2317 Human primary plaque cell cultures to study mechanisms of atherosclerosis
Buono, M. F.; Benavente, E. D.; Slenders, L.; Methorst, D.; Tessels, D.; Mili, E.; Finger, R.; Kapteijn, D.; Daniels, M.; van den Dungen, N. A. M.; Calis, J. J. A.; Mol, B. M.; de Borst, G. J.; de Kleijn, D.; Pasterkamp, G.; den Ruijter, H. M.; Mokry, M.
10.1101/2023.02.09.527800 — cell biology — Posted on 2023-02-13
2318 Genetic markers and tree properties predicting wood biorefining potential in aspen (Populus tremula) bioenergy feedstock
Escamez, S.; Robinson, K. M.; Luomaranta, M.; Gandla, M. L.; Mahler, N.; Yassin, Z.; Grahn, T.; Scheepers, G.; Stener, L.-G.; Jonsson, L. J.; Jansson, S.; Street, N.; Tuominen, H.
10.1101/2021.07.06.450716 — plant biology — Posted on 2023-02-13
2319 PhysiCOOL: A generalized framework for model Calibration and Optimization Of modeLing projects
Goncalves, I. G.; Hormuth, D. A.; Prabhakaran, S.; Phillips, C. M.; Garcia-Aznar, J. M.
10.1101/2022.11.17.516671 — bioengineering — Posted on 2023-02-13
2321 SID-1 regulates a retrotransposon-encoded gene to tune heritable RNA silencing
Shugarts, N.; Sathya, A.; Yi, A. L.; Chan, W. M.; Marre, J. A.; Jose, A. M.
10.1101/2021.10.05.463267 — genetics — Posted on 2023-02-13
2324 Stabilisation of β-Catenin-WNT signalling by USP10 in APC-truncated colorectal cancer drives cancer stemness and enables super-competitor signalling
Reissland, M.; Hartmann, O.; Tauch, S.; Prieto-Garcia, C.; Schulte, C.; Solvie, D.; Loebbert, S.; Jacomin, A. C.; Pesic, M.; Bugter, J. M.; Schuelein-Voelk, C.; Fuss, C.; Pahor, N.; Ade, C.; Buck, V.; Potente, M.; Li, V.; Beliu, G.; Wiegering, A.; Bitman-Lotan, E.; Grossmann, T.; Rosenfeldt, M.; Eilers, M.; Maric, H.; Maurice, M. M.; Greten, F.; Dikic, I.; Orian, A.; Gallant, P.; Diefenbacher, M. E.
10.1101/2023.02.10.527983 — cancer biology — Posted on 2023-02-13
2326 Reduction of oligomer size modulates the competition between cluster formation and phase separation of the tumor suppressor SPOP
Sabri, N.; Cuneo, M. J.; Marzahn, M. R.; Lee, J.; Bouchard, J. J.; Vaithiyalingam, S.; Borgia, M. B.; Schmit, J. D.; Mittag, T.
10.1101/2023.02.11.528154 — biophysics — Posted on 2023-02-13
2328 Flow Physics Explains Morphological Diversity of Ciliated Organs
Nawroth, J. C.; Ling, F.; Essock-Burns, T.; Stein, D.; McFall-Ngai, M.; Katija, K.; Shelley, M. J.; Kanso, E.
10.1101/2023.02.12.528181 — biophysics — Posted on 2023-02-13
2329 Androgen Signaling Restricts Glutaminolysis to Drive Sex-Specific Th17 Metabolism
Chowdhury, N. U.; Cephus, J.-Y.; Madden, M. Z.; Wolf, M. M.; Chi, C.; Sugiura, A.; Stier, M. T.; Voss, K.; Ye, X.; Kuehnle, S. N.; Scales, K.; Gandhi, V. D.; Guzy, R. D.; Cahill, K. N.; Sperling, A. I.; Peebles, R. S.; Rathmell, J.; Newcomb, D. C.
10.1101/2023.02.10.527741 — immunology — Posted on 2023-02-13
2330 Brain-wide associations between white matter and agehighlight the role of fornix microstructure in brain age
Korbmacher, M.; de Lange, A. M.; van der Meer, D.; Beck, D.; Eikefjord, E. N.; Lundervold, A.; Andreassen, O.; Westlye, L. T.; Maximov, I. I.
10.1101/2022.09.29.510029 — neuroscience — Posted on 2023-02-13
2333 SeqScreen-Nano: a computational platform for rapid, in-field characterization of previously unseen pathogens.
Balaji, A.; Liu, Y.; Nute, M. G.; Hu, B.; Kappell, A.; LeSassier, D.; Godbold, G. D.; Ternus, K. L.; Treangen, T. J.
10.1101/2023.02.10.528096 — bioinformatics — Posted on 2023-02-13
2334 Metagenomics and Metatranscriptomics Suggest Pathways of 3-Chloroaniline Degradation in Wastewater Reactors
Seshan, H.; Santillan, E.; Constancias, F.; Chandra Segaran, U. S.; Williams, R. B. H.; Wuertz, S.
10.1101/2021.05.02.442374 — microbiology — Posted on 2023-02-13
2338 cGAS-activating lupus autoantibody for cancer immunotherapy
Chen, X.; Tang, X.; Cuffari, B. J.; Tang, C.; Gao, X.; Noble, P. W.; Young, M. R.; Turk, O. M.; Shirali, A.; Gera, J.; Nishimura, R. N.; Zhou, J.; Hansen, J. E.
10.1101/2023.02.11.527649 — immunology — Posted on 2023-02-12
2339 Single-cell Landscape Analysis Unravels Molecular Programming of the Human B Cell Compartment in Chronic GVHD
Poe, J. C.; Fang, J.; Zhang, D.; Lee, M. R.; DiCioccio, R. A.; Su, H.; Qin, X.; Zhang, J.; Visentin, J.; Bracken, S. J.; Ho, V. T.; Wang, K. S.; Rose, J. J.; Pavletic, S. Z.; Hakim, F. T.; Jia, W.; Suthers, A. N.; Curry-Chisolm, I.; Horwitz, M. E.; Rizzieri, D. A.; McManigle, W.; Chao, N. J.; Cardones, A. R.; Xie, J.; Owzar, K.; Sarantopoulos, S.
10.1101/2022.10.13.512162 — immunology — Posted on 2023-02-12
2344 Cryo-FIB workflow for imaging brain tissue via in situ cryo-electron microscopy
Ning, J.; Glausier, J. R.; Hsieh, C.; Schmelzer, T.; Buck, S. A.; Franks, J.; Hampton, C. M.; Lewis, D. A.; Marko, M.; Freyberg, Z.
10.1101/2023.02.11.528064 — neuroscience — Posted on 2023-02-12
2345 In vivo Locus Coeruleus activity while awake is associated with REM sleep quality in healthy older individuals
Koshmanova, E.; Berger, A.; Beckers, E.; Campbell, I.; Mortazavi, N.; Sharifpour, R.; Paparella, I.; Balda, F.; Berthomier, C.; Degueldre, C.; Salmon, E.; Lamalle, L.; Bastin, C.; Van Egroo, M.; Phillips, C.; Maquet, P.; Collette, F.; Muto, V.; Chylinski, D.; Jacobs, H.; Talwar, P.; Sherif, S.; Vandewalle, G.
10.1101/2023.02.10.527974 — neuroscience — Posted on 2023-02-12
2353 CVD-associated SNPs with regulatory potential drive pathologic non-coding RNA expression
Zhu, C.; Baumgarten, N.; Wu, M.; Wang, Y.; Das, A. P.; Kaur, J.; Ardakani, F. B.; Duong, T. T.; Pham, M. D.; Duda, M.; Dimmeler, S.; Yuan, T.; Schulz, M.; Krishnan, J.
10.1101/2023.02.12.528184 — genomics — Posted on 2023-02-12
2354 Multimodal single-cell analysis of non-random heteroplasmy distribution in human retinal mitochondrial disease
Mullin, N. K.; Voigt, A. P.; Flamme-Wiese, M. J.; Liu, X.; Riker, M. J.; Varzavand, K.; Stone, E. M.; Tucker, B. A.; Mullins, R. F.
10.1101/2022.06.20.496449 — genetics — Posted on 2023-02-12
2355 Targeting GDF15 as a potential therapy for low back pain originating from endplate
Li, X.; Wu, J.; Kong, Q.; Hu, M.; Wei, Z.; Jiang, H.; Zhang, Z.; Zhou, X.; ma, j.
10.1101/2023.02.11.528124 — cell biology — Posted on 2023-02-12
2357 scRNAseq of healthy and irradiated mouse parotid glands highlights crosstalk between immune and secretory cells during chronic injury
Rheinheimer, B. A.; Pasquale, M. C.; NIDCD/NIDCR Genomics and Computational Biology Core, ; Limesand, K. H.; Hoffman, M. P.; Martinez Chibly, A.
10.1101/2022.11.26.517939 — molecular biology — Posted on 2023-02-12
2358 Genomic and phenotypic evolution of nematode-infecting microsporidia
Wadi, L.; El Jarkass, H. T.; Tran, T. D.; Islah, N.; Luallen, R. J.; Reinke, A. W.
10.1101/2022.08.28.505597 — microbiology — Posted on 2023-02-12
2359 TRAF4 is crucial for the propagation of ST2+ memory Th2 cells in IL-33-mediated type 2 airway inflammation
Xiao, J.; Chen, X.; Liu, W.; Qian, W.; Bulek, K.; Hong, L.; Miller-Little, W.; Li, X.; Liu, C.
10.1101/2023.02.11.528093 — immunology — Posted on 2023-02-12
2360 Alpaca Single B Cell Interrogation and Heavy-Chain-Only Antibody Discovery on an Optofluidic Platform
Shapiro, M. B.; Boucher, J.; Brousseau, A.; Dehkharghani, A.; Gabriel, J.; Kamat, V.; Patil, K.; Gao, F.; Walker, J.; Kelly, R.; Souders, C. A.
10.1101/2023.02.10.528050 — immunology — Posted on 2023-02-12
2361 ADAM10 mediates macroglial cell fate decisions in the developing brain
Ge, W.-p.; Wang, Y.; Liang, Y.; Ai, D.; Li, J.-L.; Feng, Z.; Guo, Z.; Chen, X.-j.; Zhang, T.; zou, X.; Gao, J.-L.; Gao, X.; Hu, X.-L.; Wu, L.-J.; Sun, W.; Zhu, S.; Duan, S.; Wang, W.
10.1101/2023.02.11.527059 — neuroscience — Posted on 2023-02-12
2364 Somatotopic organization among parallel sensory pathways that promote a grooming sequence in Drosophila
Eichler, K.; Hampel, S.; Alejandro, A.; Calle, S.; Santana, A.; Kmecova, L.; Blagburn, J. M.; Hoopfer, E. D.; Seeds, A. M.
10.1101/2023.02.11.528119 — neuroscience — Posted on 2023-02-12
2365 Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction, progression, and prion-like spread of Alzheimer s disease pathogenesis
Pomeshchik, Y.; Velasquez, E.; Gil, J.; Klementieva, O.; Gidlof, R.; Sydoff, M.; Bagnoli, S.; Nacmias, B.; Sorbi, S.; Westergren-Thorsson, G.; Gouras, G. K.; Rezeli, M.; roybon, l.
10.1101/2023.02.10.527926 — neuroscience — Posted on 2023-02-12
2366 Attachment Stimuli Trigger Widespread Synchrony across Multiple Brains
Shimon-Raz, O.; Yeshurun, Y.; Ulmer-Yaniv, A.; Levinkron, A.; Salomon, R.; Feldman, R.
10.1101/2023.02.10.527970 — neuroscience — Posted on 2023-02-12
2367 Evolution of connectivity architecture in the Drosophila mushroom body
Caron, S. J. C.; Ellis, K. E.; Smihula, H.; Ganguli, I.; Vigato, E.; Bervoets, S.; Auer, T. O.; Benton, R.; Litwin Kumar, A.
10.1101/2023.02.10.528036 — neuroscience — Posted on 2023-02-12
2368 Encoding of continuous perceptual choices in human early visual cortex
Barbieri, R.; Töpfer, F. M.; Soch, J.; Bogler, C.; Sprekeler, H.; Haynes, J.-D.
10.1101/2023.02.10.527876 — neuroscience — Posted on 2023-02-12
2370 In vivo proton MR Spectroscopy of the healthy and diseased human brain
Gudmundson, A. T.; Koo, A.; Virovka, A.; Amirault, A. L.; Soo, M.; Cho, J. H.; Murali-Manohar, S.; Oeltzschner, G. T.; Edden, R. A.; Barker, P. B.; Stark, C. E.
10.1101/2023.02.10.528046 — neuroscience — Posted on 2023-02-12
2371 Sensory innervation of masseter, temporal and lateral pterygoid muscles in common marmosets
Akopian, A.; Ruparel, S.; Hovhannisyan, A. H.; Lindquist, K.; Tram, M.; Perez, D.; Mecklenburg, J.; Salmon, A.; Merlo, J.; Corey, T.
10.1101/2023.02.10.528062 — neuroscience — Posted on 2023-02-12
2372 Hierarchical cortical and subcortical mechanisms underlying binocular rivalry
Qian, C.; Chen, Z.; Hollander, G. d.; Knapen, T.; Zhang, Z.; He, S.; Zhang, P.
10.1101/2023.02.11.528110 — neuroscience — Posted on 2023-02-12
2374 Experienced Meditators Show Multifaceted Attention-Related Differences in Neural Activity
Bailey, N.; Baell, O.; Payne, J.; Humble, G.; Geddes, H.; Cahill, I.; Hill, A. T.; Chung, S.; Emonson, M.; Murphy, O.; Fitzgerald, P.
10.1101/2023.02.10.527999 — neuroscience — Posted on 2023-02-12
2376 Spatial Tuning of Alpha Oscillations in Human Visual Cortex
Yuasa, K.; Groen, I. I. A.; Piantoni, G.; Montenegro, S.; Flinker, A.; Devore, S.; Devinsky, O.; Doyle, W.; Dugan, P.; Friedman, D.; Ramsey, N.; Petridou, N.; Winawer, J.
10.1101/2023.02.11.528137 — neuroscience — Posted on 2023-02-12
2379 Distributed representations of prediction error signals across the cortical hierarchy are synergistic
Gelens, F.; Aijala, J.; Komatsu, M.; Uran, C.; Jensen, M. A.; Miller, K. J.; Ince, R. A. A.; Vinck, M.; Canales-Johnson, A.
10.1101/2023.01.12.523735 — neuroscience — Posted on 2023-02-12
2381 Self-assembly of nanofilaments in cyanobacteria for protein co-localization
Zedler, J. A. Z.; Schirmacher, A. M.; Russo, D. A.; Hodgson, L.; Gundersen, E.; Matthes, A.; Frank, S.; Verkade, P.; Jensen, P. E.
10.1101/2023.02.12.528169 — synthetic biology — Posted on 2023-02-12
2383 The clock transcription factor BMAL1 is a key regulator of extracellular matrix homeostasis and cell fate in the intervertebral disc
Dudek, M.; Morris, H.; Rogers, N.; Pathiranage, D. R.; Chan, D.; Kadler, K. E.; Hoyland, J. A.; Meng, Q.-J.
10.1101/2023.02.12.528214 — physiology — Posted on 2023-02-12
2384 Co-inhibition of topoisomerase 1 and BRD4-mediated pause release selectively kills pancreatic cancer via readthrough transcription
Cameron, D. P.; Grosser, J.; Ladigan, S.; Kuzin, V.; Iliopoulou, E.; Wiegard, A.; Benredjem, H.; Liffers, S. T.; Lueong, S.; Cheung, P. F.; Vangala, D.; Pohl, M.; Viebahn, R.; Teschendorf, C.; Wolters, H.; Usta, S.; Geng, K.; Kutter, C.; Arsenian-Henriksson, M.; Siveke, J. T.; Tannapfel, A.; Schmiegel, W.; Hahn, S. A.; Baranello, L.
10.1101/2023.02.10.527824 — cancer biology — Posted on 2023-02-12
2385 A non-canonical function of LDHB promotes SLC7A11-mediated glutathione metabolism and protects against glutaminolysis-dependent ferroptosis in KRAS-driven lung cancer
Zhao, L.; Deng, H.; Zhang, J.; Zamboni, N.; Geest, G. A.; Yang, H.; Yang, Z.; Gao, Y.; Xu, D.; Zhong, H.; Bruggmann, R.; Zhou, Q.; Schmid, R. A.; Marti, T.; Dorn, P.; Peng, R.-W.
10.1101/2023.02.12.525859 — cancer biology — Posted on 2023-02-12
2387 Foreign RNA spike-ins enable accurate allele-specific expression analysis at scale
Mendelevich, A.; Gupta, S.; Pakharev, A.; Teodosiadis, A.; Mironov, A. A.; Gimelbrant, A. A.
10.1101/2023.02.11.528027 — bioinformatics — Posted on 2023-02-12
2389 The Genome of the Soybean Gall Midge (Resseliella maxima)
Melotto, G.; Jones, M.; Bosley, K.; Flack, N.; Frank, L. E.; Jacobson, E.; Kipp, E. J.; Nelson, S.; Ramirez, M.; Walls, C.; Koch, R. L.; Lindsey, A. R. I.; Faulk, C.
10.1101/2023.02.10.528044 — genomics — Posted on 2023-02-12
2392 The dominance of coinfecting parasites' indirect effects on host traits
Bolnick, D. I.; Arruda, S.; Polania, C.; Simonse, L.; Padhiar, A. A.; Roth, A.; Rodgers, M.
10.1101/2023.02.12.528182 — evolutionary biology — Posted on 2023-02-12
2394 Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36
Barrachina, M. N.; Pernes, G.; Becker, I. C.; Allaeys, I.; Hirsch, T. I.; Groeneveld, D. J.; Khan, A. O.; Freire, D.; Guo, K.; Carminita, E.; Morgan, P. K.; Collins, T. J.; Mellett, N.; Wei, Z.; Almazni, I.; Italiano, J. E.; Luyendyk, J.; Meikle, P. J.; Puder, M.; Morgan, N. V.; Boilard, E.; Murphy, A. J.; Machlus, K. R.
10.1101/2023.02.12.527706 — cell biology — Posted on 2023-02-12
2397 The long and short of it: Benchmarking viromics using Illumina, Nanopore and PacBio sequencing technologies
Cook, R.; Brown, N.; Rihtman, B.; Michniewski, S.; Redgwell, T.; Stekel, D. J.; Hobman, J.; Chen, Y.; Nelson, A.; Scanlan, D.; Jones, M. A.; Smith, D.; Millard, A. D.
10.1101/2023.02.12.527533 — microbiology — Posted on 2023-02-12
2398 Deep sequencing of the T cell Receptor reveals common and reproducible CD8+ signatures of response to checkpoint immunotherapy
Watson, R. A.; Taylor, C.; Tong, O.; Cooper, R. A.; Jungkurth, E.; Kumar Sharma, P.; Storey, B.; Ye, W.; Sun, B.; de los Aires, A.; Matos Santo, F.; Nassiri, I.; Gilchrist, J.; Ieremia, E.; Middleton, M. R.; Fairfax, B. P.
10.1101/2023.02.11.528080 — immunology — Posted on 2023-02-12
2399 Tau-mediated synaptic dysfunction is coupled with HCN channelopathy
Goniotaki, D.; Tamagnini, F.; Biasetti, L.; Rumpf, S. L.; Pollack, S.; Ukwesa, S.; Sun, H.; Serpell, L.; Noble, W.; Staras, K.; Hanger, D.
10.1101/2020.11.08.369488 — neuroscience — Posted on 2023-02-12
2402 Highly efficient induction of functionally mature excitatory neurons from feeder-free human ES/iPS cells
Zhou, Z.; Kakegawa, W.; Fujimori, K.; Sho, M.; Shimamura, R.; Supakul, S.; Yoshimatsu, S.; Kohyama, J.; Yuzaki, M.; Okano, H.
10.1101/2023.02.10.528087 — neuroscience — Posted on 2023-02-12
2403 Decoding the content of working memory in school-aged children
Turoman, N.; Fiave, P. A.; Zahnd, C.; deBettencourt, M. T.; Vergauwe, E.
10.1101/2023.02.10.527990 — neuroscience — Posted on 2023-02-12
2406 Neural signatures of declarative memory cueing using odors during sleep
Sanchez-Corzo, A.; Baum, D. M.; Irani, M.; Hinrichs, S.; Reisenegger, R.; Whitaker, G. A.; Born, J.; Klinzing, J. G.; Sitaram, R.
10.1101/2023.02.10.527339 — neuroscience — Posted on 2023-02-12
2407 Parallel Neurodegenerative Phenotypes in Sporadic Parkinsons Disease Fibroblasts and Midbrain Dopamine Neurons
Corenblum, M. J.; McRobbie-Johnson, A.; Carruth, E.; Bernard, K.; Luo, M.; Mandarino, L. J.; Peterson, S.; Billheimer, D.; Maley, T.; Eggers, E. D.; Madhavan, L.
10.1101/2023.02.10.527867 — neuroscience — Posted on 2023-02-12
2408 Temporal Dynamics of Normalization Reweighting
Baker, D. H.; Marinova, D.; Aveyard, R.; Hargreaves, L. J.; Renton, A.; Castellani, R.; Hall, P.; Harmens, M.; Holroyd, G.; Nicholson, B.; Williams, E. L.; Hobson, H. M.; Wade, A. R.
10.1101/2023.02.10.527994 — neuroscience — Posted on 2023-02-12
2409 Pervasive environmental chemicals impair oligodendrocyte development
Cohn, E. F.; Clayton, B. L. L.; Madhavan, M.; Yacoub, S.; Federov, Y.; Paul-Friedman, K.; Shafer, T. J.; Tesar, P.
10.1101/2023.02.10.528042 — neuroscience — Posted on 2023-02-12
2412 Human sensorimotor beta event characteristics and aperiodic signal are highly heritable
Pauls, K. A. M.; Salmela, E.; Korsun, O.; Kujala, J.; Salmelin, R.; Renvall, H.
10.1101/2023.02.10.527950 — neuroscience — Posted on 2023-02-12
2413 The ATR inhibitor elimusertib exhibits anti-lymphoma activity and synergizes with the PI3K inhibitor copanlisib
Sartori, G.; Tarantelli, C.; Spriano, F.; Gaudio, E.; Cascione, L.; Mascia, M.; Barreca, M.; Arribas, A. J.; Licenziato, L.; Golino, G.; Ferragamo, A.; Pileri, S.; Damia, G.; Zucca, E.; Stathis, A.; Politz, O.; Wengner, A. M.; Bertoni, F.
10.1101/2023.02.10.528011 — cancer biology — Posted on 2023-02-12
2415 Efficient generation of transgene-free canker-resistant Citrus sinensis using Cas12a/crRNA ribonucleoprotein
Su, H.; wang, y.; Xu, J.; Omar, A.; Grosser, J.; Calovic, M.; Zhang, L.; Vakulskas, C.; Wang, N.
10.1101/2023.02.12.528187 — bioengineering — Posted on 2023-02-12
2420 Truncated titin is integrated into the human dilated cardiomyopathic sarcomere
Kellermayer, D.; Tordai, H.; Kiss, B.; Török, G.; Peter, D. M.; Sayour, A. A.; Polos, M.; Hartyanszky, I.; Szilveszter, B.; Labeit, S.; Gango, A.; Bedics, G.; Bödör, C.; Radovits, T.; Merkely, B.; Kellermayer, M.
10.1101/2023.02.08.527678 — biophysics — Posted on 2023-02-12
2422 Pathogen genetics identifies avirulence/virulence loci associated with barley chromosome 6H resistance in the Pyrenophora teres f. teres - barley interaction
Li, J.; Wyatt, N. A.; Skiba, R. M.; Kariyawasam, G. K.; Richards, J. K.; Effertz, K.; Rehman, S.; Brueggeman, R. S.; Friesen, T. L.
10.1101/2023.02.10.527674 — genetics — Posted on 2023-02-12
2424 Type I interferon shapes brain distribution and tropism of tick-borne flavivirus
Chotiwan, N.; Rosendal, E.; Willekens, S. M. A.; Schexnaydre, E.; Nilsson, E.; Lindqvist, R.; Hahn, M.; Mihai, I. S.; Morini, F.; Zhang, J.; Ebel, G.; Carlson, L.-A.; Henriksson, J.; Ahlgren, U.; Marcellino, D.; Overby, A. K.
10.1101/2021.11.16.468804 — microbiology — Posted on 2023-02-12
2425 Functional binding of PD1 ligands predicts response to anti-PD1 treatment in cancer patients
Kaufman, B.; Abramov, O.; Yevko, A.; Apple, D.; Shlapobersky, M.; Greenshpan, Y.; Shaco-Levy, R.; Rouvinov, K.; Livoff, A.; Elkabets, M.; Porgador, A.
10.1101/2023.02.09.527671 — immunology — Posted on 2023-02-12
2430 Systematic Analysis of the Functional Overlap among Plant YTHDF proteins
Flores-Tellez, D.; Tankmar, M. D.; von Büllow, S.; Chen, J.; Lindorff-Larsen, K.; Brodersen, P.; Arribas-Hernandez, L.
10.1101/2022.10.19.512826 — molecular biology — Posted on 2023-02-12
2431 Spatio-temporal summation of perimetric stimuli in healthy observers
Montesano, G.; Mulholland, P.; Garway-Heath, D. F.; Evans, J.; Ometto, G.; Crabb, D. P.
10.1101/2022.08.10.503485 — neuroscience — Posted on 2023-02-12
2432 Transcriptomic profiles of stress susceptibility and resilience in the amygdala and hippocampus
Long, K. L. P.; Muroy, S. E.; Sorooshyari, S.; Ko, M. J.; Jaques, Y.; Sudmant, P. H.; Kaufer, D.
10.1101/2023.02.08.527777 — neuroscience — Posted on 2023-02-12
2433 Conserved Chamber-Specific Polyploidy Maintains Heart Function in Drosophila
Chakraborty, A.; Peterson, N.; King, J.; Gross, R.; Pla, M. M.; Thennavan, A.; Zhou, K.; Deluca, S.; Bursac, N.; Bowles, D.; Wolf, M.; Fox, D. T.
10.1101/2023.02.10.528086 — developmental biology — Posted on 2023-02-12
2435 Structure, signals, and cellular elements of the mouse gastric mesenchymal niche
Manieri, E.; Tie, G.; Seruggia, D.; Madha, S.; Maglieri, A. H.; Huang, K.; Fujiwara, Y.; Zhang, K.; Orkin, S. H.; McCarthy, N.; Shivdasani, R. A.
10.1101/2023.02.11.527728 — cell biology — Posted on 2023-02-12
2437 Emergence of High-Order Functional Hubs in the Human Brain
Santos, F. A. N.; Tewarie, P. K. B.; Baudot, P.; Luchicchi, A.; Barros de Souza, D. A. N.; Girier, G.; Milan, A. P.; Broeders, T.; Centeno, E. G. Z.; Cofre, R.; Rosas, F. E.; Carone, D.; Kennedy, J.; Stam, C. J.; Hillebrand, A.; Desroches, M.; Rodrigues, S.; Schoonheim, M.; Douw, L.; Quax, R.
10.1101/2023.02.10.528083 — neuroscience — Posted on 2023-02-12
2438 Multiplexed Subspaces Route Neural Activity Across Brain-wide Networks
MacDowell, C. J.; Libby, A.; Jahn, C. I.; Tafazoli, S.; Buschman, T. J.
10.1101/2023.02.08.527772 — neuroscience — Posted on 2023-02-12
2439 Cognitive relevance of an evolutionarily new and variable prefrontal structure
Willbrand, E. H.; Jackson, S.; Chen, S.; Hathaway, C. B.; Voorhies, W. I.; Bunge, S. A.; Weiner, K. S.
10.1101/2023.02.10.528061 — neuroscience — Posted on 2023-02-12
2440 Deep learning-based codon optimization with large-scale synonymous variant datasets enables generalized tunable protein expression
Constant, D. A.; Gutierrez, J. M.; Sastry, A. V.; Viazzo, R.; Smith, N. R.; Hossain, J.; Spencer, D. A.; Carter, H.; Ventura, A. B.; Louie, M. T. M.; Kohnert, C.; Consbruck, R.; Bennett, J.; Crawford, K. A.; Sutton, J. M.; Morrison, A.; Steiger, A. K.; Jackson, K. A.; Stanton, J. T.; Abdulhaqq, S.; Hannum, G.; Meier, J.; Weinstock, M.; Gander, M.
10.1101/2023.02.11.528149 — synthetic biology — Posted on 2023-02-12
2443 Glutathione supports lipid abundance in vivo
Asantewaa, G.; Tuttle, E. T.; Ward, N. P.; Kang, Y. P.; Kim, Y.; Kavanagh, M. E.; Girnius, N.; Chen, Y.; Duncan, R.; Rodriguez, K.; Hecht, F.; Zocchi, M.; Smorodintsev-Schiller, L.; Scales, T. Q.; Taylor, K.; Alimohammadi, F.; Sechrist, Z. R.; Agoustini-Vulaj, D.; Schafer, X. L.; Chang, H.; Smith, Z.; O'Connor, T. N.; Whelan, S.; Selfors, L. M.; Crowdis, J.; Gray, G. K.; Bronson, R. T.; Brenner, D.; Ruffini, A.; Dirksen, R. T.; Hazel, A. F.; Huber, A. R.; Munger, J.; Cravatt, B. F.; Vasiliou, V.; Cole, C. L.; DeNicola, G. M.; Harris, I. S.
10.1101/2023.02.10.524960 — biochemistry — Posted on 2023-02-12
2444 Chemoproteomic Profiling Reveals that Anti-Cancer Natural Product Dankastatin B Covalently Targets Mitochondrial VDAC3
Belcher, B. P.; Machicao, P. A.; Tong, B.; Ho, E.; Friedli, J.; So, B.; Bui, H.; Isobe, Y.; Maimone, T. J.; Nomura, D. K.
10.1101/2023.02.11.528139 — biochemistry — Posted on 2023-02-12
2445 Phylogenetic distance and structural diversity directing a reclassification of glycopeptide antibiotics
Gavriilidou, A.; Adamek, M.; Rodler, J.-P.; Kubach, N.; Kremer, S.; Huson, D.; Cryle, M.; Stegmann, E.; Ziemert, N.
10.1101/2023.02.10.526856 — genetics — Posted on 2023-02-11
2446 Cytokine-Mediated Degradation of the Transcription Factor ERG Impacts the Pulmonary Vascular Response to Systemic Inflammatory Challenge
Schafer, C.; Martin-Almedina, S.; Kurylowicz, K.; Dufton, N. P.; Osuna-Almagro, L.; Wu, M.-L.; Johnson, C.; Shah, A.; Haskard, D. O.; Buxton, A.; Willis, E.; Wheeler, K.; Turner, S.; Chlebicz, M.; Scott, R.; Kovats, S.; Cleuren, A.; Birdsey, G. M.; Randi, A. M.; Griffin, C. T.
10.1101/2023.02.08.527788 — cell biology — Posted on 2023-02-11
2449 Simulated microgravity during clino-rotation is disturbed by spurious fluid motion
Mansour, J.; Berwanger, C.; Jung, M.; Eichinger, L.; Fabry, B.; Clemen, C. S.
10.1101/2023.02.10.527979 — cell biology — Posted on 2023-02-12
2452 Stabilisation of β-Catenin-WNT signalling by USP10 in APC-truncated colorectal cancer drives cancer stemness and enables super-competitor signalling
Reissland, M.; Hartmann, O.; Tauch, S.; Prieto-Garcia, C.; Schulte, C.; Solvei, D.; Loebbert, S.; Jacomin, A. C.; Pesic, M.; Bugter, J. M.; Schuelein-Voelk, C.; Fuss, C.; Pahor, N.; Ade, C.; Buck, V.; Potente, M.; Li, V.; Beliu, G.; Wiegering, A.; Bitman-Lotan, E.; Grossmann, T.; Rosenfeldt, M.; Eilers, M.; Maric, H.; Maurice, M.; Greten, F.; Dikic, I.; Orian, A.; Gallant, P.; Diefenbacher, M. E.
10.1101/2023.02.10.527983 — cancer biology — Posted on 2023-02-11
2453 Mechanically activated bone cells drive vessel formation via an extracellular vesicle mediated mechanism
Shen, N.; Maggio, M.; Woods, I.; Eichholz, K.; Stavenschi, E.; Lowery, M.; Roche, F. M.; Hokamp, K.; O'Driscoll, L.; Hoey, D. A.
10.1101/2023.02.10.527969 — bioengineering — Posted on 2023-02-11
2454 Changes in social behaviour with alterations of MAPK3 and KCTD13/CUL3 pathways in two new outbred rat models for the 16p11.2 syndromes with autism spectrum disorders.
Martin Lorenzo, S.; Muniz Moreno, M. d. M.; Atas, H.; Pellen, M.; Nalesso, V.; Raffelsberger, W.; Prevost, G.; Lindner, L.; Birling, M.-C.; Menoret, S.; Tesson, L.; Negroni, L.; Concordet, J.-P.; Anegon, I.; Herault, Y.
10.1101/2023.02.11.528123 — animal behavior and cognition — Posted on 2023-02-11
2455 Interchromosomal segmental duplication drives translocation and loss of P. falciparum histidine-rich protein 3 in Americas and Africa
Hathaway, N. J.; Kim, I. E.; Young, N. W.; Hui, S. T.; Crudale, R.; Giesbrecht, D.; Liang, E. Y.; Nixon, C. P.; Juliano, J. J.; Parr, J. B.; Bailey, J. A.
10.1101/2022.12.07.519189 — genomics — Posted on 2023-02-11
2458 Modulation of the E-cadherin in human cells infected in vitro with Coxiella burnetii
OMAR OSMAN, I.; Mezouar, S.; BRAHIM BELHAOUARI, D.; MEGE, J.-L.; Devaux, C. A.
10.1101/2022.12.08.519566 — microbiology — Posted on 2023-02-11
2459 STAT3 protects HSCs from intrinsic interferon signaling and loss of long-term blood-forming activity
Patel, B.; Zhou, Y.; Babcock, R. L.; Ma, F.; Zal, M. A.; Kumar, D.; Medik, Y. B.; Kahn, L. M.; Pineda, J. E.; Park, E. M.; Tang, X.; Raso, M. G.; Zal, T.; Clise-Dwyer, K.; Giancotti, F. G.; Colla, S.; Watowich, S. S.
10.1101/2023.02.10.528069 — immunology — Posted on 2023-02-11
2461 Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance
Li, F.; Wang, Y.; Hwang, I.; Janng, J.-Y.; Zhou, L.; Deng, Z.; Yu, E. Y.; Cai, Y.; Wu, C.; Han, Z.; Huang, Y.-H.; Huang, X.; Zhang, L.; Yao, J.; Lue, N.; Lieberman, P.; Ying, H.; Paik, J.; Zheng, H.
10.1101/2023.02.10.528023 — cancer biology — Posted on 2023-02-11
2462 Cryo-EM Structure of a Human LECT2 Amyloid Fibril Reveals a Network of Polar Ladders at its Core
Richards, L. S.; Flores, M. D.; Zink, S.; Schibrowsky, N. A.; Sawaya, M. R.; Rodriguez, J. A.
10.1101/2023.02.08.527771 — biochemistry — Posted on 2023-02-11
2464 Long-term epidemiology and evolution of swine influenza viruses in Vietnam
Cheung, J.; Bui, A. N.; Younas, S.; Edwards, K. M.; Nguyen, H. Q.; Pham, N. T.; Bui, V. N.; Peiris, M.; Dhanasekaran, V.
10.1101/2023.02.08.527780 — microbiology — Posted on 2023-02-11
2466 GATA1 knockout in human pluripotent stem cells generates enhanced neutrophils to investigate extracellular trap formation
Harper, T. C.; Oberlick, E. M.; Smith, T. J.; Nunes, D. E.; Bray, M. A.; Park, S.; Driscoll, C. D.; Mowbray, S. F.; Antczak, C.
10.1101/2023.02.08.526339 — immunology — Posted on 2023-02-11
2467 The Bouma law accounts for crowding in fifty observers
Kurzawski, J. W.; Burchell, A.; Thapa, D.; Majaj, N. J.; Winawer, J. A.; Pelli, D. G.
10.1101/2021.04.12.439570 — neuroscience — Posted on 2023-02-11
2468 Improved cognitive-motor processing speed and decreased functional connectivity after high intensity aerobic exercise in individuals with chronic stroke
Andrushko, J. W.; Rinat, S.; Greeley, B.; Larssen, B. C.; Jones, C. B.; Rubino, C.; Denyer, R.; Ferris, J.; Campbell, K. L.; Neva, J. L.; Boyd, L. A.
10.1101/2023.01.15.523513 — neuroscience — Posted on 2023-02-11
2469 Tumor cell-adipocyte gap junctions activate lipolysis and are essential for breast tumorigenesis
Camarda, R.; Williams, J.; Malkov, S.; Zimmerman, L. J.; Manning, S.; Aran, D.; Beardsley, A.; Van de Mark, D.; Chen, Y.; Berdan, C. A.; Louie, S. M.; Mahieu, C.; Superville, D.; Gruner, M.; Winkler, J.; Willey, E.; Gagnon, J. D.; Shinoda, K.; Ansel, K. M.; Werb, Z.; Nomura, D. K.; Kajimura, S.; Butte, A. J.; Sanders, M. E.; Liebler, D. C.; Rugo, H.; Krings, G.; Shepherd, J. A.; Goga, A.
10.1101/277939 — cancer biology — Posted on 2023-02-11
2471 Dynamic recycling of extracellular ATP in human epithelial intestinal cells
Saffioti, N. A.; Alvarez, C. L.; Bazzi, Z. K.; Gentilini, M. V.; Gondolesi, G.; Schwarzbaum, P. J.; Schachter, J.
10.1101/2023.02.10.527987 — biochemistry — Posted on 2023-02-11
2472 Crystal structures reveal the framework of cis-acyltransferase modular polyketide synthases
Keatinge-Clay, A. T.; Miyazawa, T.; Zhang, J.; Ray, K. A.; Lutgens, J.; Bista, R.; Lin, S. N.
10.1101/2023.02.11.528132 — biochemistry — Posted on 2023-02-11
2473 Thrombin activation of the factor XI dimer is a multi-staged process for each subunit
Bar Barroeta, A.; Albanese, P.; Marquart, A.; Meijers, J. C. M.; Scheltema, R. A.
10.1101/2023.02.11.528103 — biochemistry — Posted on 2023-02-11
2474 Glucocorticoids negatively relate to body mass on the short-term in a free-ranging ungulate
Lalande, L. D.; Gilot-Fromont, E.; Carbillet, J.; Debias, F.; Duhayer, J.; Gaillard, J.-M.; Lemaitre, J.-F.; Palme, R.; Pardonnet, S.; Pellerin, M.; Rey, B.; Vuarin, P.
10.1101/2022.09.15.508076 — ecology — Posted on 2023-02-11
2475 The ecdysone receptor promotes or suppresses proliferation according toligand level
Perez-Mockus, G.; Cocconi, L.; Alexandre, C.; Aerne, B. L.; Salbreux, G.; Vincent, J.-P.
10.1101/2023.02.10.527985 — developmental biology — Posted on 2023-02-11
2476 Fluctuations and entropy enable neural crest cell ingression
Pasiliao, C. C.; Thomas, E. C.; Yung, T.; Zhu, M.; Tao, H.; Sun, Y.; Goyal, S.; Hopyan, S.
10.1101/2023.02.10.528070 — developmental biology — Posted on 2023-02-11
2479 RNPS1 stabilizes NAT10 protein to facilitate translation in cancer via tRNA ac4C modification
Wang, X.; Li, K.; Cheng, M.; Xu, H.; Chen, J.; Peng, X.; Ling, R.; Chen, J.; Wan, Y.; Ke, L.; Zhang, C.; Zhang, Q.; Zou, Y.; Chen, F.; Chen, Z.; Chen, S.; Li, J.; Peng, L.; Chen, Q.; Wang, C.; Liu, Q.; Chen, D.
10.1101/2023.02.11.528122 — molecular biology — Posted on 2023-02-11
2481 Cooperation and cheating orchestrate Vibrio assemblages and polymicrobial synergy in oysters infected with OsHV-1 virus
Oyanedel, D.; Lagorce, A.; Bruto, M.; Haffner, P.; Morot, A.; Dorant, Y.; de La Forest Divonne, S.; Delavat, F.; Inguimbert, N.; Montagnani, C.; Morga, B.; Toulza, E.; Chaparro, C.; Escoubas, J.-M.; Labreuche, Y.; Gueguen, Y.; Vidal-Dupiol, J.; de Lorgeril, J.; Petton, B.; Degremont, L.; Tourbiez, D.; Pimpare, L.-L.; Leroy, M.; Romatif, O.; Pouzadoux, J.; Mitta, G.; Le Roux, F.; Charriere, G. M.; Travers, M.-A.; Destoumieux-Garzon, D.
10.1101/2023.02.11.528104 — microbiology — Posted on 2023-02-11
2483 Aberrant MNX1 Expression Associated with t(7;12)(q36;p13) Pediatric Acute Myeloid 1 Leukemia Induces the Disease Through Altering Histone Methylation
Waraky, A.; Ostlund, A.; Nilsson, T.; Weichenhan, D.; Lutsik, P.; Baehr, M.; Hey, J.; Adamsson, J.; Morsy, M. H. A.; Li, S.; Fogelstrand, L.; Plass, C.; Palmqvist, L.
10.1101/2022.06.10.495634 — cancer biology — Posted on 2023-02-11
2485 Long-term balancing selection and the genetic load linked to the self-incompatibility locus in Arabidopsis halleri and A. lyrata.
Le Veve, A.; Burghgraeve, N.; Genete, M.; Lepers-Blassiau, C.; Takou, M.; De Meaux, J.; Mable, B. K.; Durand, E.; Vekemans, X.; Castric, V.
10.1101/2022.04.12.487987 — genomics — Posted on 2023-02-11
2487 Industrial chicory genome gives insight into the molecular time table of anther development and male sterility
Waegneer, E.; Rombauts, S. M.; Baert, J.; Dauchot, N.; De Keyser, A.; Eeckhaut, T.; Haegeman, A.; Liu, C.; Maudoux, O.; Notte, C.; Staelens, A.; Van der Veken, J.; Van Laere, K.; Ruttink, T.
10.1101/2023.02.08.527727 — plant biology — Posted on 2023-02-11
2488 Reanalysis of mtDNA mutations of human primordial germ cells (PGCs) reveals NUMT contamination and suggests that selection in PGCs may be positive
Fleischmann, Z.; Cote-L'Heureux, A.; Franco, M.; Oreshkov, S.; Annis, S.; Khrapko, M.; Aidlen, D.; Popadin, K.; Woods, D. C.; Tilly, J. L.; Khrapko, K.
10.1101/2022.12.12.520138 — genomics — Posted on 2023-02-11
2489 Apelin improves angiogenesis and blood flow reperfusion following lower limb ischemia in diabetic mice
Robillard, S.; Tran, K.; Brazeau, T.; Boisvert, E.; Lizotte, F.; Auger-Messier, M.; Boudreault, P.-L.; Marsault, E.; Geraldes, P.
10.1101/2023.02.08.527688 — cell biology — Posted on 2023-02-11
2490 CDK5 activity in retinal pigment epithelium contributes to gap junction dynamics during phagocytosis
Fadjukov, J.; Wienbar, S.; Milicevic, N.; Hakanen, S.; Vihinen-Ranta, M.; Ihalainen, T. O.; Schwartz, G. W.; Nymark, S.
10.1101/2023.02.09.527850 — cell biology — Posted on 2023-02-11
2495 Female gene networks are expressed in myofibroblast-like smooth muscle cells in vulnerable atherosclerotic plaques.
Benavente, E. D.; Karnewar, S.; Buono, M. F.; Mili, E.; Hartman, R. J. G.; Kapteijn, D.; Slenders, L.; Daniels, M.; Aherrahrou, R.; Reinberger, T.; Mol, B. M.; de Borst, G. J.; de Kleijn, D.; Prange, K. H.; Depuydt, M. A.; de Winther, M. P.; Kuiper, J.; Björkegren, J. L.; Erdmann, J.; Civelek, M.; Mokry, M.; Owens, G. K.; Pasterkamp, G.; den Ruijter, H. M.
10.1101/2023.02.08.527690 — bioinformatics — Posted on 2023-02-11
2500 Transcriptional Cartography Integrates Multiscale Biology of the Human Cortex
Wagstyl, K.; Adler, S.; Seidlitz, J.; Vandekar, S.; Mallard, T. T.; Dear, R.; DeCasien, A. R.; Satterthwaite, T. T.; Liu, S.; Vertes, P. E.; Shinohara, R. T.; Alexander-Bloch, A.; Geschwind, D. H.; Raznahan, A.
10.1101/2022.06.13.495984 — neuroscience — Posted on 2023-02-11
2503 Mutational meltdown in asexual populations doomed to extinction
Olofsson, P.; Chipkin, L.; Daileda, R. C.; Azevedo, R. B. R.
10.1101/448563 — evolutionary biology — Posted on 2023-02-11
2504 A Potent and Selective CDKL5/GSK3 Chemical Probe is Neuroprotective
Ong, H. W.; Liang, Y.; Richardson, W.; Lowry, E. R.; Wells, C. I.; Chen, X.; Silvestre, M.; Dempster, K.; Silvaroli, J. A.; Smith, J. L.; Wichterle, H.; Pabla, N. S.; Ultanir, S. K.; Bullock, A. N.; Drewry, D.; Axtman, A. D.
10.1101/2023.02.09.527935 — cell biology — Posted on 2023-02-11
2505 Modulation of the E-cadherin in human cells infected in vitro with Coxiella burnetii
OMAR OSMAN, I.; Mezouar, S.; BRAHIM BELHAOUARI, D.; MEGE, J.-L.; Devaux, C. A.
10.1101/2022.12.08.519566 — microbiology — Posted on 2023-02-11
2506 IFNγ and acute prenatal infection with Toxoplasma gondii activate fetal hematopoietic stem cells
Lopez, D. A.; Otsuka, K. S.; Apostol, A. C.; Posada, J.; Sanchez-Arcila, J. C.; Jensen, K. D.; Beaudin, A. E.
10.1101/2022.11.29.518417 — immunology — Posted on 2023-02-11
2507 Sema7A and Sema4D Heterodimerization is Essential for Membrane Targeting and Neocortical Wiring
Bessa, P.; Newman, A. G.; Yan, K.; Schaub, T.; Dannenberg, R.; Lajko, D.; Eilenberger, J.; Brunet, T.; Textoris-Taube, K.; Kemmler, E.; Banerjee, P.; Ravindran, E.; Muelleder, M.; Preisner, R.; Grosschedl, R.; Rosario, M.; Tarabykin, V.
10.1101/2023.02.10.527998 — neuroscience — Posted on 2023-02-10
2508 Adolescent neurostimulation of dopamine circuit reverses genetic deficits in frontal cortex function
Mastwal, S.; Li, X.; Stowell, R. D.; Manion, M.; Zhang, W.; Kim, N.-S.; Yoon, K.-J.; Song, H.; Ming, G.-L.; Wang, K. H.
10.1101/2023.02.03.526987 — neuroscience — Posted on 2023-02-11
2511 Fluctuations and entropy enable neural crest cell ingression
Pasiliao, C. C.; Thomas, E. C.; Yung, T.; Zhu, M.; Tao, H.; Sun, Y.; Goyal, S.; Hopyan, S.
10.1101/2023.02.10.528070 — developmental biology — Posted on 2023-02-10
2513 Mechanical forces at the kidney filtration barrier govern spatial orientation of podocyte processes on capillaries
Unnersjoe-Jess, D.; Ramdedovic, A.; Butt, L.; Plagmann, I.; Hoehne, M.; Hackl, A.; Blom, H.; Schermer, B.; Benzing, T.
10.1101/2023.02.10.528006 — cell biology — Posted on 2023-02-10
2517 The genomic landscape of swine influenza A viruses in Southeast Asia
Zeller, M. A.; Ma, J.; Wong, F. Y.; Tum, S.; Hidano, A.; Holt, H.; Chhay, T.; Sorn, S.; Koeut, D.; Seng, B.; Chao, S.; Ng, G. G.; Yan, Z.; Chou, M.; Rudge, J. W.; Smith, G. J.; Su, Y. C.
10.1101/2023.02.10.527943 — microbiology — Posted on 2023-02-10
2518 Retrospective identification of intrinsic factors that mark pluripotency potential in rare somatic cells
Jain, N.; Goyal, Y.; Dunagin, M. C.; Cote, C. J.; Mellis, I. A.; Emert, B.; Jiang, C. L.; Dardani, I. P.; Reffsin, S.; Raj, A.
10.1101/2023.02.10.527870 — systems biology — Posted on 2023-02-10
2521 ZEB1 controls a lineage-specific transcriptional program essential for melanoma cell state transitions
TANG, Y.; Durand, S.; Pommier, R. M.; Benboubker, V.; Grimont, M.; Cumunel, E.; Boivin, F.; Dupeuble, F.; Barbollat, L.; Eberhardt, A.; Plaschka, M.; Dalle, S.; CARAMEL, J.
10.1101/2023.02.10.526467 — cancer biology — Posted on 2023-02-10
2523 The structural architecture of an α-synuclein toxic oligomer
Santos, J.; Cuellar, J.; Pallares, I.; Byrd, E. J.; Lends, A.; Moro, F.; Abdul-Shukkoor, M. B.; Pujols, J.; Velasco-Carneros, L.; Sobott, F.; Otzen, D. E.; Calabrese, A. N.; Muga, A.; Pedersen, J. S.; Loquet, A.; Valpuesta, J. M.; Radford, S.; Ventura, S.
10.1101/2023.02.10.527650 — biophysics — Posted on 2023-02-10
2524 Identification and analysis of individuals who deviate from their genetically-predicted phenotype
Hawkes, G.; Yengo, L.; Vendantam, S.; Marouli, E.; Beaumont, R. N.; the GIANT Consortium, ; Tyrrell, J.; Weedon, M. N.; Hirschhorn, J.; Frayling, T.; Wood, A. R.
10.1101/2023.02.10.528019 — genetics — Posted on 2023-02-10
2525 An immune cell lipid atlas reveals the basis of susceptibility to ferroptosis
Pernes, G.; Morgan, P. K.; Huynh, K.; Giles, C.; Paul, S.; Smith, A. A. T.; Mellett, N. A.; Bertuzzo Veiga, C.; Collins, T. J.; De Silva, T. M.; Lee, M. K.; Meikle, P. J.; Lancaster, G. I.; Murphy, A. J.
10.1101/2023.02.10.528075 — cell biology — Posted on 2023-02-10
2526 Circular mitochondrial-encoded mRNAs are a distinct subpopulation of mitochondrial mRNA in Trypanosoma brucei
Smoniewski, C. M.; Mirzavand Borujeni, P.; Petersen, A.; Hampton, M.; Salavati, R.; Zimmer, S. L.
10.1101/2023.02.10.528059 — molecular biology — Posted on 2023-02-10
2527 The yeast RNA methylation complex consists of conserved yet reconfigured components with m6A-dependent and independent roles
Ensinck, I.; Maman, A.; Albihlal, W.; Lassandro, M.; Salzano, G.; Sideri, T.; Howell, S.; Calvani, E.; Patel, H.; Bushkin, G. G.; Snijders, A. P.; Ralser, M.; Skehel, M.; Casanal, A.; Schwartz, S.; van Werven, F.
10.1101/2023.02.10.528004 — molecular biology — Posted on 2023-02-10
2528 Mechanistic Modeling Explains the Production Dynamics of Recombinant Adeno-Associated Virus with the Baculovirus Expression Vector System
Destro, F.; Srinivasan, P.; Kanter, J. M.; Neufeld, C.; Wolfrum, J. M.; Barone, P. W.; Springs, S. L.; Sinskey, A. J.; Cecchini, S.; Kotin, R. M.; Braatz, R. D.
10.1101/2023.02.04.527082 — molecular biology — Posted on 2023-02-10
2529 Age-associated changes in endothelial transcriptome and chromatin landscape correlate with elevated risk of hemorrhage
Mohan, K.; Gasparoni, G.; Salhab, A.; Orlich, M.; Geffers, R.; Hoffmann, S.; Adams, R. H.; Walter, J.; Nordheim, A.
10.1101/2023.02.10.528012 — molecular biology — Posted on 2023-02-10
2530 Recruitment of apolipoprotein E facilitates Herpes simplex virus 1 release
Liu, L.; Thorsteinsson, K.; Jayaweera, S. W.; Avinens, D.; Bano, F.; Conca, D. V.; Lovheim, H.; Olofsson, A.; Bally, M.
10.1101/2023.02.10.526562 — microbiology — Posted on 2023-02-10
2531 Helminth infection impacts hematopoiesis
Wijshake, T.; Wang, J.; Rose, J.; Marlar-Pavey, M.; Collins, J. J.; Agathocleous, M.
10.1101/2023.02.10.528073 — immunology — Posted on 2023-02-10
2532 The vestibular calyceal junction is dismantled following subchronic streptomycin in rats and sensory epithelium stress in humans
Maroto, A. F.; Borrajo, M.; Prades, S.; Callejo, A.; Amilibia, E.; Perez-Grau, M.; Roca-Ribas, F.; Castellanos, E.; Barrallo-Gimeno, A.; Llorens, J.
10.1101/2022.05.17.492294 — neuroscience — Posted on 2023-02-10
2535 Proposal and extensive test of a calibration protocol for crop phenology models
Wallach, D.; Palosuo, T.; Thorburn, P.; Mielenz, H.; Buis, S.; Hochman, Z.; Gourdain, E.; Garcia, C.; Andrianasolo, F.; Dumont, B.; Ferrise, R.; Gaiser, T.; Gayler, S.; Hiremath, S.; Horan, H.; Hoogenboom, G.; Jansson, P.-E.; Jing, Q.; Qian, B.; Harrison, M.; Justes, E.; Kersebaum, K.-C.; Launay, M.; Lewan, E.; Mequanint, F.; Liu, K.; Moriondo, M.; Nendel, C.; Padovan, G.; Schuetze, N.; Seserman, D.-M.; Souissi, A.; Shelia, V.; Specka, X.; Srivastava, A. K.; Trombi, G.; Weber, T.; Weihermueller, L.; Woehling, T.; Seidel, S.
10.1101/2022.06.08.495355 — plant biology — Posted on 2023-02-10
2536 A deep learning workflow for quantification of Micronuclei in DNA damage studies in cultured cancer cell lines: a proof of principle investigation
Surendranath, K.; Panchbhai, A.; Ishanzadeh, M. C.; Pankanti, S.; Sidali, A.; Solaiman, N.; Radhakrishnan, K.; Murphy, J. J.
10.1101/2022.09.18.508405 — cancer biology — Posted on 2023-02-10
2538 Neural coding of temperature with a DNA-based spiking chemical neuron
Lobato-Dauzier, N.; Baccouche, A.; Gines, G.; Levi, T.; Rondelez, Y.; Fujii, T.; Kim, S. H.; Aubert-Kato, N.; Genot, A. J.
10.1101/2022.07.06.498929 — biochemistry — Posted on 2023-02-10
2539 Prosocial behavior, social reward and affective state discrimination in adult male and female mice
Misiolek, K.; Klimczak, M.; Chroszcz, M.; Szumiec, L.; Bryksa, A.; Przyborowicz, K.; Rodriguez Parkitna, J.; Harda, Z.
10.1101/2022.08.19.504492 — animal behavior and cognition — Posted on 2023-02-10
2546 Gut microbiome signatures of Yorkshire Terrier Enteropathy during disease and remission.
Doulidis, P. G.; Galler, A. I.; Hausmann, B.; Berry, D.; Rodriguez Rojas, A.; Burgener, I. A.
10.1101/2022.08.25.505284 — microbiology — Posted on 2023-02-10
2547 Hospital and urban wastewaters shape the structure and active resistome of environmental biofilms
Buelow, E.; Dauga, C.; Carrion, C.; Mathe-Hubert, H.; Achaibou, S.; Gaschet, M.; Jove, T.; Chesneau, O.; Kennedy, S. P.; Ploy, M.-C.; Da Re, S.; DAGOT, C.
10.1101/2023.01.19.524754 — microbiology — Posted on 2023-02-10
2550 MISPEL: A supervised deep learning harmonizationmethod for multi-scanner neuroimaging data
Torbati, M. E.; Minhas, D. S.; Laymon, C. M.; Maillard, P.; Wilson, J. D.; Chen, C.-L.; Crainiceanu, C. M.; DeCarli, C. S.; Hwang, S. J.; Tudorascu, D. L.
10.1101/2022.07.27.501786 — neuroscience — Posted on 2023-02-10
2552 Effect of the SARS-CoV-2 Delta-associated G15U mutation on the s2m element dimerization and its interactions with miR-1307-3p
Cunningham, C. L.; Frye, C. J.; Makowski, J. A.; Kensinger, A. H.; Shine, M.; Milback, E. J.; Lackey, P. E.; Evanseck, J. D.; Mihailescu, M. R.
10.1101/2023.02.10.528014 — biochemistry — Posted on 2023-02-10
2553 Antagonistic pleiotropy plays an important role in governing the evolution and genetic diversity of SARS-CoV-2
Lee, D.-C.; Tai, J.-H.; Lin, H.-F.; Chao, T.-L.; Ruan, Y.; Cheng, Y.-W.; Chou, Y.-C.; Lin, Y.-Y.; Chang, S.-Y.; Chen, P.-J.; Yeh, S.-H.; Wang, H.-Y.
10.1101/2023.02.10.527437 — evolutionary biology — Posted on 2023-02-10
2554 Long COVID manifests with T cell dysregulation, inflammation, and an uncoordinated adaptive immune response to SARS-CoV-2
Yin, K.; Peluso, M. J.; Thomas, R.; Shin, M.-G.; Neidleman, J.; Luo, X.; Hoh, R.; Anglin, K.; Huang, B.; Argueta, U.; Lopez, M.; Valdivieso, D.; Asare, K.; Ibrahim, R.; Standker, L.; Lu, S.; Goldberg, S. A.; Lee, S. A.; Lynch, K. L.; Kelly, J. D.; Martin, J. N.; Muench, J.; Deeks, S. G.; Henrich, T. J.; Roan, N. R.
10.1101/2023.02.09.527892 — immunology — Posted on 2023-02-10
2555 SARS-CoV-2 NSP5 Antagonizes the MHC II Antigen Presentation Pathway by Hijacking Histone Deacetylase 2
Taefehshokr, N.; Lac, A.; Vrieze, A. M.; Dickson, B. H.; Guo, P. N.; Jung, C.; Blythe, E. N.; Fink, C.; Dekaban, G. A.; Heit, B.
10.1101/2023.02.10.528032 — immunology — Posted on 2023-02-10
2556 Comparing the evolutionary dynamics of predominant SARS-CoV-2 virus lineages co-circulating in Mexico
Castelan-Sanchez, H. G.; Delaye, L.; Inward, R. P.; Dellicour, S.; Gutierrez, B.; Martinez de la Vina, N.; Boukadida, C.; Pybus, O.; de Anda Jauregui, G.; Guzman, P.; Flores Garrido, M.; Fontanelli, O.; Rosales, M. H.; Meneses, A.; Olmedo-Alvarez, G.; Herrera-Estrella, A.; Sanchez-Flores, A.; Munoz-Medina, J. E.; Comas-Garcia, A.; Gomez-Gil, B.; Zarate, S.; Taboada, B.; Lopez, S.; Arias, C. F.; Kraemer, M. U. G.; Lazcano, A.; Escalera-Zamudio, M.
10.1101/2022.07.05.498834 — evolutionary biology — Posted on 2023-02-10
2558 Scalable co-sequencing of RNA and DNA from individual nuclei
Olsen, T. R.; Talla, P.; Furnari, J.; Bruce, J. N.; Canoll, P.; Zha, S.; Sims, P. A.
10.1101/2023.02.09.527940 — genomics — Posted on 2023-02-10
2559 The evolutionary history of spines: a Cenozoic arms race with mammals
Gelin, U.; Charles-Dominique, T.; Davies, T. J.; Svenning, J.-C.; Bond, W. J.; Tomlinson, K. W.
10.1101/2023.02.09.527903 — evolutionary biology — Posted on 2023-02-10
2563 Condensate formation of the human RNA-binding protein SMAUG1 is controlled by its intrinsically disordered regions and interactions with 14-3-3 proteins
Fehilly, J.; Carey, O.; O'Leary, E. T.; O'Shea, S.; Juda, K.; Fitzel, R.; Selvaraj, P.; Lindsay, A. J.; Meszaros, B.; Dean, K.
10.1101/2023.02.09.527857 — molecular biology — Posted on 2023-02-10
2567 Lung injury induces a polarized immune response by self antigen-specific Foxp3+ regulatory T cells
Shin, D. S.; Ratnapriya, S.; Cashin, C. N.; Kuhn, L. F.; Rahimi, R. A.; Anthony, R. M.; Moon, J. J.
10.1101/2023.02.09.527896 — immunology — Posted on 2023-02-10
2569 The Burden of Reliability: How Measurement Noise Limits Brain-Behaviour Predictions
Gell, M.; Eickhoff, S. B.; Omidvarnia, A.; Kueppers, V.; Patil, K. R.; Satterthwaite, T. D.; Mueller, V. I.; Langner, R.
10.1101/2023.02.09.527898 — neuroscience — Posted on 2023-02-10
2570 Neuropeptide Y-expressing dorsal horn inhibitory interneurons gate spinal pain and itch signalling
Boyle, K. A.; Polgar, E.; Gutierrez-Mecinas, M.; Dickie, A. C.; Cooper, A. H.; Bell, A. M.; Jumolea, E.; Casas-Benito, A.; Watanabe, M.; Hughes, D. I.; Weir, G.; Riddell, J.; Todd, A. J.
10.1101/2023.02.10.528013 — neuroscience — Posted on 2023-02-10
2572 Distribution of ubiquilin 2 and TDP-43 aggregates throughout the CNS in UBQLN2 p.T487I-linked amyotrophic lateral sclerosis and frontotemporal dementia
Nementzik, L. R.; Thumbadoo, K. M.; Murray, H. C.; Gordon, D.; Yang, S.; Blair, I. P.; Turner, C.; Faull, R. L.; Curtis, M. A.; McLean, C.; Nicholson, G. A.; Swanson, M. E.; Scotter, E. L.
10.1101/2023.02.10.527924 — neuroscience — Posted on 2023-02-10
2575 TidyGEO: Preparing analysis-ready datasets from Gene Expression Omnibus
Mecham, A.; Stephenson, A.; Quinteros, B. I.; Salmons, G.; Piccolo, S. R.
10.1101/2023.02.09.527930 — bioinformatics — Posted on 2023-02-10
2579 A small molecule cocktail for robust induction of blood-brain barrier properties
Porkolab, G.; Meszaros, M.; Szecsko, A.; Vigh, J. P.; Walter, F. R.; Figueiredo, R.; Kalomista, I.; Vizsnyiczai, G.; Jan, J.-S.; Gosselet, F.; Vastag, M.; Veszelka, S.; Deli, M. A.
10.1101/2023.02.09.527899 — bioengineering — Posted on 2023-02-10
2582 Conservation and Expansion of Transcriptional Factor Repertoire in the Fusarium oxysporum Species Complex
Yu, H.; Yang, H.; Haridas, S.; Hayes, R. D.; Lynch, H.; Andersen, S.; Li, G.; Martinez-Soto, D.; Milo-Cochavi, S.; Hazal Ayhan, D.; Zhang, Y.; Grigoriev, I. V.; Ma, L.-J.
10.1101/2023.02.09.527873 — genomics — Posted on 2023-02-10
2583 A Four "Core Genotypes" rat model to distinguish mechanisms underlying sex-biased phenotypes and diseases
Arnold, A. P.; Chen, X.; Grzybowski, M.; Ryan, J. M.; Sengelaub, D. R.; Mohanroy, T.; Furlan, V. A.; Grisham, W.; Malloy, L.; Takizawa, A.; Wiese, C. B.; Vergnes, L.; Skaletsky, H.; Page, D. C.; Reue, K.; Harley, V. R.; Dwinell, M.; Geurts, A.
10.1101/2023.02.09.527738 — genetics — Posted on 2023-02-10
2585 Reconstructing colonization dynamics to establish how human activities transformed island biodiversity
Tomlinson, S.; Lomolino, M.; Haythorne, S.; Anderson, A.; Austin, J.; Brown, S. C.; Perry, G.; Wilmshurst, J.; Wood, J.; Fordham, D. A.
10.1101/2023.02.09.526923 — ecology — Posted on 2023-02-10
2591 A versatile CRISPR-based system for lineage tracing in living plants
Dona, M.; Bradamante, G.; Bogojevic, Z.; Gutzat, R.; Streubel, S.; Mosiolek, M.; Dolan, L.; Mittelsten Scheid, O.
10.1101/2023.02.09.527713 — cell biology — Posted on 2023-02-10
2592 Enhanced Branched-Chain Amino Acid Metabolism Improves Age-related Reproductive Function
Lesnik, C.; Sohrabi, S.; Ashraf, J.; Kaletsky, R.; Cota, V.; Sengupta, T.; Keyes, W.; Murphy, C. T.
10.1101/2023.02.09.527915 — cell biology — Posted on 2023-02-10
2593 A Potent and Selective CDKL5/GSK3 Chemical Probe is Neuroprotective
Ong, H. W.; Liang, Y.; Richardson, W.; Lowry, E. R.; Wells, C. I.; Chen, X.; Silvestre, M.; Dempster, K.; Silvaroli, J. A.; Smith, J. L.; Wichterle, H.; Pabla, N. S.; Ultanir, S. K.; Bullock, A. N.; Drewry, D.; Axtman, A. D.
10.1101/2023.02.09.527935 — cell biology — Posted on 2023-02-10
2594 Single cell transcriptomics identifies adipose tissue CD271+ progenitors for enhanced angiogenesis in limb ischemia
Inoue, O.; Goten, C.; Hashimuko, D.; Yamaguchi, K.; Takeda, Y.; Nomura, A.; Ootsuji, H.; Takashima, S.; Iino, K.; Takemura, H.; Halurkar, M.; Lim, H.-W.; Hwa, V.; Sanchez-Gurmaches, J.; Usui, S.; Takamura, M.
10.1101/2023.02.09.527726 — cell biology — Posted on 2023-02-10
2595 Regulatory principles of human mitochondrial gene expression revealed by kinetic analysis of the RNA life cycle
McShane, E.; Couvillion, M.; Ietswaart, R.; Prakash, G.; Smalec, B. M.; Soto, I.; Baxter-Koenigs, A. R.; Choquet, K.; Churchman, L. S.
10.1101/2023.02.09.527880 — cell biology — Posted on 2023-02-10
2598 Cell state transition analysis identifies interventions that improve control of M. tuberculosis infection by susceptible macrophages
Yabaji, S. M.; Rukhlenko, O. S.; Chatterjee, S.; Bhattacharya, B.; Wood, E.; Kasaikina, M.; Kholodenko, B.; Gimelbrant, A. A.; Kramnik, I.
10.1101/2023.02.09.527908 — immunology — Posted on 2023-02-10
2599 Comprehensive Allergen Profile of Blomia tropicalis Provides Insights into the Component-Resolved Diagnosis of Mite Allergy
XIONG, Q.; Liu, X.; Wan, A. T.-Y.; Malainual, N.; Xiao, X.; Tang, M.-F.; Ng, J. K.-W.; Shin, S.-K.; Sio, Y. Y.; WANG, M.; Sun, B.; Leung, T.-F.; Chew, F. T.; Tungtrongchitr, A.; Tsui, S. K.-W.
10.1101/2023.02.09.527948 — immunology — Posted on 2023-02-10
2600 The iron-dopamine D1 coupling modulates neural signatures of working memory across adulthood
Gustavsson, J.; Johansson, J.; Falahati, F.; Andersson, M.; Papenberg, G.; Avelar-Pereira, B.; Bäckman, L.; Kalpouzos, G.; Salami, A.
10.1101/2023.02.09.527840 — neuroscience — Posted on 2023-02-10
2601 Development of White Matter Fiber Covariance Networks Supports Executive Function in Youth
Bagautdinova, J.; Bourque, J.; Sydnor, V. J.; Cieslak, M.; Alexander-Bloch, A. F.; Bertolero, M. A.; Cook, P. A.; Gur, R. C.; Gur, R. E.; Larsen, B.; Moore, T. M.; Radhakrishnan, H.; Roalf, D. R.; Shinohara, R. T.; Tapera, T. M.; Zhao, C.; Sotiras, A.; Davatzikos, C.; Satterthwaite, T. D.
10.1101/2023.02.09.527696 — neuroscience — Posted on 2023-02-10
2604 Severe neurometabolic phenotype in npc1-/- zebrafish with a C-terminal mutation
Quelle Regaldie, A.; Gandoy Fieiras, N.; R Villamayor, P.; Maceiras, S.; Losada, A. P.; Folgueira, M.; Cabezas, P.; Barreiro-Iglesias, A.; Villar-Lopez, M.; Quiroga-Berdeal, M. I.; Sanchez, L.; Sobrido, M. J.
10.1101/2023.02.09.527822 — neuroscience — Posted on 2023-02-10
2605 Brain tissue cerebrospinal fluid fraction increases quadratically in normal aging
Zhou, L.; Li, Y.; Sweeney, E. M.; Wang, X. H.; Kuceyeski, A.; Chang, G. C.; Wang, Y.; Ivanidze, J.; Gauthier, S. A.; de Leon, M. J.; Nguyen, T. D.
10.1101/2023.02.09.527912 — neuroscience — Posted on 2023-02-10
2606 Neuroticism/negative emotionality is associated with increased reactivity to uncertain threat in the bed nucleus of the stria terminalis, not the amygdala
Grogans, S. E.; Hur, J.; Barstead, M. G.; Anderson, A. S.; Islam, S.; Kim, H. C.; Kuhn, M.; Tillman, R. M.; Fox, A. S.; Smith, J. F.; DeYoung, K. A.; Shackman, A. J.
10.1101/2023.02.09.527767 — neuroscience — Posted on 2023-02-10
2607 Extracellular Matrix Regulates Neuronal Chloride Concentration via K+-Cl--Cotransporter 2
Yelhekar, T. D.; Kuznetsova, T.; Malinina, E.; Ponimaskin, E.; Dityatev, A.; Druzin, M.; Johansson, S.
10.1101/2023.02.09.527837 — neuroscience — Posted on 2023-02-10
2608 Stochastic Modeling of Tinnitus Loudness
Kwak, S.; Lee, D.; Jang, S.; Kim, S.; Kim, S.; Doo, W.; Kwak, E.
10.1101/2023.02.09.527783 — neuroscience — Posted on 2023-02-10
2611 Telomerase reverse transcriptase (TERT)-expressing cells mark a novel stem cell population in the adult mouse brain
Jensen, G. S.; Beaulieu, A. N.; Curtis, C. D.; Passarelli, J.; Blaszkiewicz, M.; Thomas, S.; Morin, T.; Willows, J. W.; Greco, C. W.; Brennan, C. J.; Aniapam, C.; Caron, L.; Alves, M. J.; Lynes, M. D.; Carlone, D. L.; Breault, D. T.; Townsend, K. L.
10.1101/2023.02.09.527879 — neuroscience — Posted on 2023-02-10
2614 Plastid fatty acid export (FAX) proteins in Arabidopsis thaliana - the role of FAX1 and FAX3 in growth and development
Bugaeva, W.; Koennel, A.; Peter, J.; Mees, J.; Hankofer, V.; Schick, C.; Schmidt, A.; Banguela-Castillo, A.; Philippar, K.
10.1101/2023.02.09.527856 — plant biology — Posted on 2023-02-10
2616 Cholesteryl hemiazelate Identified in Cardiovascular Disease Patients Causes in vitro and in vivo Inflammation
Domingues, N.; Gaifem, J.; Matthiesen, R.; Saraiva, D.; Bento, L.; Marques, A.; Soares, I.; Sampaio, J.; Klose, C.; Surma, M.; Almeida, M.; Mendes, G.; Goncalves, P.; Ferreira, J.; Gouveia e Melo, R.; Mendes Pedro, L.; Simons, K.; Pinho e Melo, T.; Cabral, G.; Jacinto, A.; Silvestre, R.; Vaz, W.; Vieira, O. V.
10.1101/2023.02.09.527823 — pathology — Posted on 2023-02-10
2617 Diffsig: Associating Risk Factors With Mutational Signatures
Park, J.-E.; Smith, M. A.; Van Alsten, S. C.; Walens, A.; Wu, D.; Hoadley, K. A.; Troester, M. A.; Love, M. I.
10.1101/2023.02.09.527740 — cancer biology — Posted on 2023-02-10
2618 Chemoresistome Mapping in Individual Breast Cancer Patients Unravels Diversity in Dynamic Transcriptional Adaptation
Dadiani, M.; Friedlander, G.; Perry, G.; Balint-Lahat, N.; Gilad, S.; Morzaev-Sulzbach, D.; Bossel Ben-Moshe, N.; Pavlovski, A.; Domany, E.; Shenoy, A.; Barshack, I.; Geiger, T.; Kaufman, B.; Gal-Yam, E. N.
10.1101/2023.02.09.527790 — cancer biology — Posted on 2023-02-10
2620 GENIUS: GEnome traNsformatIon and spatial representation of mUltiomicS data
Sokac, M.; Dyrskjot Andersen, L.; Haibe-Kains, B.; Aerts, H. J. W. L.; Juul Birkbak, N.
10.1101/2023.02.09.525144 — bioinformatics — Posted on 2023-02-10
2623 Metaphor - A workflow for streamlined assembly and binning of metagenomes
Salazar, V. W.; Shabban, B.; del Mar Quiroga, M.; Turnbull, R.; Tescari, E.; Marcelino, V. R.; Verbruggen, H.; Le Cao, K.-A.
10.1101/2023.02.09.527784 — bioinformatics — Posted on 2023-02-10
2625 Benchmarking Variational AutoEncoders on cancer transcriptomics data
elTager, M.; Abdelaal, T.; Charrout, M.; Mahfouz, A.; Reinders, M.; Makrodimitris, S.
10.1101/2023.02.09.527832 — bioinformatics — Posted on 2023-02-10
2626 CPA-Perturb-seq: Multiplexed single-cell characterization of alternative polyadenylation regulators
Kowalski, M. H.; Wessels, H.-H.; Linder, J. S. A.; Choudhary, S.; Hartman, A.; Hao, Y.; Mascio, I.; Dalgarno, C.; Kundaje, A.; Satija, R.
10.1101/2023.02.09.527751 — genomics — Posted on 2023-02-10
2630 COVFlow: virus phylodynamics analyses from selected SARS-CoV-2 sequences
Danesh, G.; Boennec, C.; Verdurme, L.; Roussel, M.; Trombert, S.; Visseaux, B.; Haim-Boukobza, S.; Alizon, S.
10.1101/2022.06.17.496544 — bioinformatics — Posted on 2023-02-10
2636 Disentangling the effects of metabolic cost and accuracy on movement vigor
Bruening, G. W.; Sukumar, S.; Courter, R. J.; O'Brien, M. K.; Ahmed, A. A.
10.1101/2023.02.08.527734 — neuroscience — Posted on 2023-02-10
2638 First Mass Mortality of Marine Mammals Caused by Highly Pathogenic Influenza Virus (H5N1) in South America
Gamarra-Toledo, V.; Plaza, P.; Inga, G.; Gutierrez, R.; Garcia-Tello, O.; Valdivia-Ramirez, L.; Huaman-Mendoza, D.; Nieto-Navarrete, J.; Ventura, S.; Lambertucci, S. A.
10.1101/2023.02.08.527769 — pathology — Posted on 2023-02-10
2639 Oncogenic drivers dictate immune control of acute myeloid leukemia.
Austin, R. J.; Straube, J.; Halder, R.; Janardhanan, Y.; Bruedigam, C.; Witkowski, M.; Cooper, L.; Porter, A.; Braun, M.; Souza-Fonseca-Guimaraes, F.; Minnie, S. A.; Cooper, E.; Jacquelin, S.; Song, A.; Bald, T.; Nakamura, K.; Hill, G. R.; Aifantis, I.; Lane, S. W.; Bywater, M. J.
10.1101/2023.02.08.527448 — cancer biology — Posted on 2023-02-10
2640 Prediction and experimental evidence of differentgrowth phases of the Podospora anserina hyphalnetwork
Ledoux, C.; Chapeland-Leclerc, F.; Ruprich-Robert, G.; Bobee, C.; Lalanne, C.; Herbert, E.; David, P.
10.1101/2023.02.08.527651 — biophysics — Posted on 2023-02-10
2642 BioNAR: An Integrated Biological Network Analysis Package in Bioconductor
Mclean, C. D.; Sorokin, A.; Simpson, I.; Armstrong, J. D.; Sorokina, O.
10.1101/2023.02.08.527636 — bioinformatics — Posted on 2023-02-10
2643 Pharmacodynamic model of PARP1 inhibition and global sensitivity analyses can lead to cancer biomarker discovery
Mertins, S. D.; Isenberg, N. M.; Reyes, K.-R.; Yoon, B.-J.; Urban, N.; Jogalekar, M. P.; Diolaiti, M. E.; Weil, M. R.; Stahlberg, E. A.
10.1101/2023.02.08.527527 — bioinformatics — Posted on 2023-02-10
2644 Adaptive Digital Tissue Deconvolution
Görtler, F.; Mensching-Buhr, M.; Skaar, O.; Schrod, S.; Beissbarth, T.; Joshi, A.; Zacharias, H. U.; Grellscheid, S. N.; Altenbuchinger, M.
10.1101/2023.02.08.527583 — bioinformatics — Posted on 2023-02-10
2645 Unipept Desktop 2.0: construction of targeted reference protein databases for proteogenomics analyses
Verschaffelt, P.; Tanca, A.; Abbondio, M.; Van Den Bossche, T.; Vande Moortele, T.; Dawyndt, P.; Martens, L.; Mesuere, B.
10.1101/2023.02.09.527820 — bioinformatics — Posted on 2023-02-10
2647 Nicotinic acetylcholine receptor signaling maintains epithelial barrier integrity
Katheder, N. S.; Browder, K. C.; Chang, D.; De Maziere, A.; Kujala, P.; van Dijk, S.; Klumperman, J.; Lai, Z.; Sangaraju, D.; Jasper, H.
10.1101/2023.02.09.527809 — genetics — Posted on 2023-02-10
2649 Coevolution with a seed bank
Schwartz, D. A.; Shoemaker, W. R.; Magalie, A.; Weitz, J.; Lennon, J. T.
10.1101/2023.02.08.527722 — evolutionary biology — Posted on 2023-02-10
2650 Learning virus genotype-fitness landscape in embedding space
Liu, Y.; Luo, Y.; Lu, X.; Gao, H.; He, R.; Zhang, X.; Zhang, X.; Li, Y.
10.1101/2023.02.09.527693 — evolutionary biology — Posted on 2023-02-10
2656 NLRP1 inflammasome modulates senescence and senescence-associated secretory phenotype
Muela-Zarzuela, I.; Suarez-Rivero, J. M.; Gallardo-Orihuela, A.; Wang, C.; Izawa, K.; de Gregorio-Procopio, M.; Couillin, I.; Ryffel, B.; Kitaura, J.; Sanz, A.; von Zglinicki, T.; Mbalaviele, G.; Cordero, M. D.
10.1101/2023.02.06.527254 — immunology — Posted on 2023-02-10
2658 Inflammation induces bitter taste oversensitization via epigenetic changes in Tas2r gene clusters
Lin, C.; Jyotaki, M.; Quinlan, J.; Feng, S.; Zhou, M.; Jiang, P.; Matsumoto, I.; Huang, L.; Ninomiya, Y.; Margolskee, R. F.; Reed, D. R.; Wang, H.
10.1101/2023.02.08.527520 — neuroscience — Posted on 2023-02-10
2659 Structural-Functional Brain Network Coupling Predicts Human Cognitive Ability
Popp, J. L.; Thiele, J. A.; Faskowitz, J.; Seguin, C.; Sporns, O.; Hilger, K.
10.1101/2023.02.09.527639 — neuroscience — Posted on 2023-02-10
2662 An actin-like filament from Clostridium botulinum exhibits a novel mechanism of filament dynamics
Koh, A.; Ali, S.; Popp, D.; Tanaka, K.; Kitaoku, Y.; Miyazaki, N.; Kenji, I.; Mitsuoka, K.; Robinson, R. C.; Narita, A.
10.1101/2022.03.07.483215 — biophysics — Posted on 2023-02-10
2666 Emergent lag phase in flux-regulation models of diauxie
Bate, F.; Amekan, Y.; Pushkin, M.; Chong, J. P. J.; Bees, M.
10.1101/2023.02.07.527446 — microbiology — Posted on 2023-02-10
2667 Back to the future: omnipresence of fetal influence on the human brain through the lifespan
Walhovd, K. B.; Krogsrud, S. K.; Amlien, I. K.; Sorensen, O.; Wang, Y.; Brathen, A. C. S.; Overbye, K.; Kransberg, J.; Mowinckel, A. M.; Magnussen, F.; Herud, M.; Haberg, A. K.; Fjell, A. M.; Vidal-Pineiro, D.
10.1101/2022.12.02.514196 — neuroscience — Posted on 2023-02-10
2670 USP10 strikes down β-catenin by dual-wielding deubiquitinase activity and phase transition potential
Wang, Y.; Mao, A.; Liu, J.; Li, P.; Zheng, S.; Tong, T.; Li, Z.; Zhang, H.; Ma, L.; Lin, J.; Pang, Z.; Han, Q.; Li, F.; Zhang, X.; Chen, M.; He, X.; Zhang, X.; Fei, T.; Liu, B.; Gao, D.; Cao, L.; Wang, Q.; Li, Y.; Sheng, R.
10.1101/2022.10.31.514466 — cell biology — Posted on 2023-02-10
2673 Translational control by Trypanosoma brucei DRBD18 contributes to the maintenance of the procyclic state
Ciganda, M.; Sotelo-Silveira, J.; Smith, J. T.; Shen, S.; Qu, J.; Smircich, P.; Read, L. K.
10.1101/2023.02.08.527724 — microbiology — Posted on 2023-02-10
2674 Multivariate adaptive shrinkage improves cross-population transcriptome prediction for transcriptome-wide association studies in underrepresented populations
Araujo, D. S.; Nguyen, C.; Hu, X.; Mikhaylova, A. V.; Gignoux, C.; Ardlie, K. G.; Taylor, K. D.; Durda, P.; Liu, Y.; Papanicolaou, G.; Cho, M. H.; Rich, S. S.; Rotter, J. I.; NHLBI TOPMed Consortium, ; Im, H. K.; Manichaikul, A. W.; Wheeler, H. E.
10.1101/2023.02.09.527747 — genomics — Posted on 2023-02-09
2676 Dissecting 16p11.2 hemi-deletion to study sex-specific striatal phenotypes of neurodevelopmental disorders
Kim, J.; Vanrobaeys, Y.; Peterson, Z.; Kelvington, B.; Gaine, M. E.; Nickl-Jockschat, T.; Abel, T.
10.1101/2023.02.09.527866 — neuroscience — Posted on 2023-02-09
2679 Evolutionarily diverse origins of honey bee deformed wing viruses
Hasegawa, N.; Techer, M.; al-Hissnawi, M.; Adjlane, N.; Antunez, K.; Beaurepaire, A.; Christmon, K.; Delatte, H.; Dukku, U.; Eliash, N.; El-Niweir, M.; Esnault, O.; Evans, J.; Haddad, N.; Locke, B.; Munoz, I.; Noel, G.; Panziera, D.; Roberts, J.; De la Rua, P.; Shebl, M.; Stanimirovic, Z.; Rasmussen, D.; Mikheyev, A.
10.1101/2023.01.21.525007 — evolutionary biology — Posted on 2023-02-09
2682 Seroprevalence of IgG Antibody against SARS-CoV-2 Nucleocapsid protein and Associated Risk Factors
Chowdhury, Y. F.; Hossen, F.; Islam, S. M. R.; Hossain, M. S.; Mahtab-Ul-Islam, K.; Chowdhury, S. I.; Hasan, M. R.; Tasnim, N.; Shaikh, M. A. A.; Karim, M. R.
10.1101/2023.02.09.527802 — immunology — Posted on 2023-02-09
2684 Metastatic potential in clonal melanoma cells is driven by a rare, early-invading subpopulation
Kaur, A.; Cuenca, L.; Kiani, K.; Busch, G.; Fingerman, D.; Dunagin, M. C.; Li, J.; Dardani, I.; Sanford, E. M.; Pemberton, J.; Goyal, Y.; Weeraratna, A. T.; Herlyn, M.; Raj, A.
10.1101/2022.04.17.488591 — cancer biology — Posted on 2023-02-09
2687 Modulation of GPR133 (ADGRD1) Signaling by its Intracellular Interaction Partner Extended Synaptotagmin 1 (ESYT1)
Stephan, G.; Liu, W.; Frenster, J.; Ravn-Boess, N.; Bready, D.; Cai, J.; Fenyo, D.; Neubert, T. A.; Placantonakis, D.
10.1101/2023.02.09.527921 — cell biology — Posted on 2023-02-09
2689 Plasmid-mediated colistin resistance among human clinical Enterobacterales isolates: National surveillance in the Czech Republic
Zelendova, M.; Papagiannitsis, C.; Sismova, P.; Medvecky, M.; Pomorska, K.; Palkovicova, J.; Nesporova, K.; Jakubu, V.; Jamborova, I.; Zemlickova, H.; Working Group for Monitoring of Antibiotic Resistance, ; Dolejska, M.
10.1101/2023.02.09.527831 — microbiology — Posted on 2023-02-09
2691 The NLRP3 inflammasome selectively drives IL-1β secretion by Pseudomonas aeruginosa infected neutrophils and regulates bacterial killing in vivo
Minns, M.; Lima, T.; Liboro, K.; Abbondante, S.; Miller, B. A.; Marshall, M.; Tran-Chau, J.; Rietsch, A.; Dubyak, G.; Pearlman, E.
10.1101/2022.04.07.487503 — microbiology — Posted on 2023-02-09
2692 PNMA2 forms non-enveloped virus-like capsids that trigger paraneoplastic neurological syndrome
Xu, J.; Erlendsson, S.; Singh, M.; Regier, M.; Ibiricu, I.; Day, G. S.; Piquet, A. L.; Clardy, S. L.; Feschotte, C.; Briggs, J. A. G.; Shepherd, J. D.
10.1101/2023.02.09.527862 — neuroscience — Posted on 2023-02-09
2694 Pumping Iron: A Multi-omics Analysis of Two Extremophilic Algae Reveals Mechanisms of Iron Economy
Davidi, L.; Gallaher, S. D.; Ben-David, E.; Purvine, S. O.; Fillmore, T. L.; Nicora, C. D.; Craig, R. J.; Schmollinger, S.; Roje, S.; Blaby-Haas, C. E.; Auber, R. P.; Wisecaver, J.; Merchant, S. S.
10.1101/2023.02.09.527888 — systems biology — Posted on 2023-02-09
2695 High Efficiency Rare Earth Element Biomining with Systems Biology Guided Engineering of Gluconobacter oxydans
Schmitz, A. M.; Pian, B.; Marecos, S.; Wu, M.; Holycross, M. E.; Gazel, E.; Reid, M. C.; Barstow, B.
10.1101/2023.02.09.527855 — synthetic biology — Posted on 2023-02-09
2698 Techniques to Produce and Evaluate Realistic Multivariate Synthetic
Heine, J.; Fowler, E. E. E.; Berglund, A.; Schell, M. J.; Eschrich, S. A.
10.1101/2021.10.26.465952 — bioinformatics — Posted on 2023-02-09
2700 Structural insights into agonist-binding and activation of the human complement C3a receptor
Yadav, M. K.; Yadav, R.; Sarma, P.; Maharana, J.; Soni, C.; Saha, S.; Singh, V.; Ganguly, M.; Saha, S.; Khant, H.; Banerjee, R.; Shukla, A. K.; Gati, C.
10.1101/2023.02.09.527835 — biochemistry — Posted on 2023-02-09
2702 Red2Flpe-SCON: A Versatile, Multicolor Strategy for Generating Mosaic Conditional Knockout Mice
Wu, S.-H. S.; Kim, S.; Lee, H.; Lee, J.-H.; Colozza, G.; Park, S.-Y.; Bakonyi, R.; Teriyapirom, I.; Hallay, N.; Pilat-Carrota, S.; Theussl, H.-C.; Kim, J.; Lee, J.-H.; Simons, B. D.; Kim, J. K.; Koo, B.-K.
10.1101/2023.02.09.527641 — genetics — Posted on 2023-02-09
2703 Interference with the HNF4-dependent gene regulatory network diminishes ER stress in hepatocytes
Shah, A.; Huck, I.; Duncan, K.; Gansemer, E. R.; Apte, U.; Stamnes, M. A.; Rutkowski, D. T.
10.1101/2023.02.09.527889 — cell biology — Posted on 2023-02-09
2704 The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart
Taliani, V.; Buonaiuto, G.; Desideri, F.; Setti, A.; Santini, T.; Galfre, S.; Schirone, L.; Mariani, D.; Frati, G.; Valenti, V.; Sciarretta, S.; Perlas, E.; Nicoletti, C.; Musaro, A.; Ballarino, M.
10.1101/2022.07.05.498800 — molecular biology — Posted on 2023-02-09
2708 Genomic adaptation of giant viruses in polar oceans
Meng, L.; Delmont, T. O.; Gaia, M.; Pelletier, E.; Fernandez-Guerra, A.; Chaffron, S.; Neches, R. Y.; Wu, J.; Kaneko, H.; Endo, H.; Ogata, H.
10.1101/2023.02.09.527846 — microbiology — Posted on 2023-02-09
2711 m6A regulates the stability of cellular transcripts required for efficient KSHV lytic replication
Manners, O.; Baquero-Perez, B.; Mottram, T. J.; Yonchev, I. D.; Trevelyan, C. J.; Patterson, M. R.; Macdonald, A.; Wilson, S. A.; Aspden, J.; Whitehouse, A.
10.1101/2023.02.09.527825 — microbiology — Posted on 2023-02-09
2714 Transmissibility of clinically relevant atovaquone-resistant Plasmodium falciparum by anopheline mosquitoes
Balta, V. A.; Stiffler, D.; Sayeed, A.; Tripathi, A. K.; Elahi, R.; Mlambo, G.; Bakshi, R. P.; Dziedzic, A. G.; Jedlicka, A. E.; Nenortas, E.; Romero-Rodriguez, K.; Canonizado, M. A.; Mann, A.; Owen, A.; Sullivan, D. J.; Prigge, S. T.; Sinnis, P.; Shapiro, T. A.
10.1101/2023.02.07.527535 — microbiology — Posted on 2023-02-09
2715 Vaginal microbial dynamics and pathogen colonization in a humanized microbiota mouse model
Mejia, M. E.; Mercado-Evans, V.; Zulk, J. J.; Ottinger, S.; Ruiz, K.; Ballard, M. B.; Britton, R. A.; Patras, K. A.
10.1101/2023.02.09.527909 — microbiology — Posted on 2023-02-09
2718 Flexible, Scalable, High Channel Count Stereo-Electrode for Recording in the Human Brain
Lee, K.; Paulk, A. C.; Ro, Y. G.; Cleary, D. R.; Tonsfeldt, K. J.; Kfir, Y.; Pezaris, J.; Tchoe, Y.; Lee, J.; Bourhis, A. M.; Vatsyayan, R.; Russman, S. M.; Yang, J. C.; Baohan, A.; Richardson, M.; Williams, Z. M.; Fried, S.; Raslan, A.; Halgren, E.; Cash, S. S.; Dayeh, S. A.
10.1101/2022.11.08.515705 — neuroscience — Posted on 2023-02-09
2719 Single-nucleus sequencing reveals enriched expression of genetic risk factors in Extratelencephalic Neurons sensitive to degeneration in ALS
Limone, F.; Mordes, D.; Couto, A.; Joseph, B.; Mitchell, J. M.; Therrien, M.; Ghosh, S. D.; Meyer, D.; Zhang, Y.; Goldman, M.; Bortolin, L.; Cobos, I.; Kadiu, I.; McCarroll, S. A.; Stevens, B.; Pietilainen, O.; Burberry, A.; Eggan, K.
10.1101/2021.07.12.452054 — neuroscience — Posted on 2023-02-09
2721 Interrogating the function of bicistronic translational control elements to improve consistency of gene expression
Jansen, Z.; Reilly, S. R.; Lieber-Kotz, M. A.; Li, A. Z.; Wei, Q.; Kulhanek, D. L.; Gilmour, A. R.; Thyer, R.
10.1101/2023.02.09.527918 — synthetic biology — Posted on 2023-02-09
2722 An RNA to rule them all: Critical steps in Lassa virus ribonucleoparticle assembly and recruitment
Saenger, L.; Williams, H. M.; Yu, D.; Vogel, D.; Kosinski, J.; Rosenthal, M.; Uetrecht, C.
10.1101/2023.02.09.527830 — biophysics — Posted on 2023-02-09
2724 Video based phenotyping platform for the laboratory mouse
Beane, G.; Geuther, B. Q.; Sproule, T. J.; Choudhary, A.; Trapszo, J.; Hession, L.; Kohar, V.; Kumar, V.
10.1101/2022.01.13.476229 — animal behavior and cognition — Posted on 2023-02-09
2727 Rapid assembly of SARS-CoV-2 genomes reveals attenuation of the Omicron BA.1 variant through NSP6
Taha, T. Y.; Chen, I. P.; Hayashi, J. M.; Tabata, T.; Walcott, K.; Kimmerly, G. R.; Syed, A. M.; Ciling, A.; Suryawanshi, R. K.; Martin, H. S.; Bach, B. H.; Tsou, C.-L.; Montano, M.; Khalid, M. M.; Sreekumar, B. K.; Kumar, G. R.; Wyman, S.; Doudna, J. A.; Ott, M.
10.1101/2023.01.31.525914 — microbiology — Posted on 2023-02-09
2728 Differences in spore size and atmospheric survival shape stark contrasts in the dispersal dynamics of two closely related fungal pathogens
Golan, J. J.; Oneto, D. L.; Ding, S.; Kessenich, R.; Sandler, M.; Rush, T.; Levitis, D.; Gevens, A.; Seminara, A.; Pringle, A.
10.1101/2023.02.08.527725 — microbiology — Posted on 2023-02-09
2729 Transcriptomic comparison of two selective retinal cell ablation paradigms in zebrafish reveals shared and cell-specific regenerative responses
Emmerich, K. B.; Walker, S. L.; Wang, G.; White, D. T.; Wang, F.; Teng, Y.; Ceisel, A.; Chunawala, Z.; Graziano, G.; Nimmagadda, S.; Saxena, M. T.; Qian, J.; Mumm, J. S.
10.1101/2020.08.04.236299 — neuroscience — Posted on 2023-02-09
2730 A low-cost device for cryoanesthesia of neonatal rodents
Jamieson, B. B.; Konstantinou, G.; Cano-Ferrer, X.; de Launoit, E.; Renier, N.; Imbert, A.; Kohl, J.
10.1101/2022.06.09.495437 — neuroscience — Posted on 2023-02-09
2731 Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis
Tomic, G.; Sheridan, C.; Refermat, A. Y.; Baggelaar, M. P.; Sipthorp, J.; Sudarshan, B.; Ocasio, C. A.; Suarez-Bonnet, A.; Priestnall, S. L.; Herbert, E.; Tate, E. W.; Downward, J.
10.1101/2023.02.08.527637 — cancer biology — Posted on 2023-02-09
2732 CLARUS: An Interactive Explainable AI Platform for Manual Counterfactuals in Graph Neural Networks
Beinecke, J. M.; Saranti, A.; Angerschmid, A.; Pfeifer, B.; Klemt, V.; Holzinger, A.; Hauschild, A.-C.
10.1101/2022.11.21.517358 — bioinformatics — Posted on 2023-02-09
2735 An umbrella review of randomized control trials on the effects of physical exercise on cognition
Ciria, L. F.; Romn-Caballero, R.; Vadillo, M. A.; Holgado, D.; Luque-Casado, A.; Perakakis, P.; Sanabria, D.
10.1101/2022.02.15.480508 — neuroscience — Posted on 2023-02-09
2736 SMRT-AgRenSeq-d in potato (Solanum tuberosum) identifies candidates for the nematode resistance Gpa5
Wang, Y.; Brown, L. H.; Adams, T. M.; Cheung, Y. W.; Li, J.; Young, V.; Todd, D. T.; Armstrong, M. R.; Neugebauer, K.; Kaur, A.; Harrower, B.; Oome, S.; Wang, X.; Bayer, M.; Hein, I.
10.1101/2022.12.08.519582 — plant biology — Posted on 2023-02-09
2737 Helixer--de novo Prediction of Primary Eukaryotic Gene Models Combining Deep Learning and a Hidden Markov Model
Holst, F.; Bolger, A.; Günther, C.; Mass, J.; Kindel, F.; Triesch, S.; Kiel, N.; Saadat, N.; Ebenhöh, O.; Usadel, B.; Schwacke, R.; Bolger, M.; Weber, A. P. M.; Denton, A. K.
10.1101/2023.02.06.527280 — bioinformatics — Posted on 2023-02-09
2738 SorCS2 binds progranulin and regulates motor axon outgrowth
Thomasen, P. B.; Salasova, A.; Login, H.; Beel, S.; Tranberg-Jensen, J.; Qvist, P.; Ovesen, P. L.; Nolte, S.; Nejsum, L.; Chao, M. V.; Dasen, J.; Van Damme, P.; Sorensen, K. K.; Oxvig, C.; Nykjaer, A.
10.1101/2023.02.08.527602 — developmental biology — Posted on 2023-02-09
2739 Glycemic challenge is associated with the rapid cellular activation of the locus ceruleus and nucleus of solitary tract: Circumscribed spatial analysis of phosphorylated MAP kinase immunoreactivity
Tapia, G. P.; Agostinelli, L. J.; Chenausky, S. D.; Salcido Padilla, J. V.; Navarro, V. I.; Alagh, A.; Si, G.; Thompson, R. H.; Balivada, S.; Khan, A. M.
10.1101/2022.08.30.504809 — neuroscience — Posted on 2023-02-09
2740 8-channel Tx dipole and 20-channel Rx loop coil array for MRI of the cervical spinal cord at 7 Tesla
Rios, N. L.; Gilbert, K. M.; Papp, D.; Cereza, G.; Foias, A.; Rangaprakash, D.; May, M. W.; Guerin, B.; Wald, L. L.; Keil, B.; Stockmann, J. P.; Barry, R. L.; Cohen-Adad, J.
10.1101/2023.02.08.527664 — bioengineering — Posted on 2023-02-09
2744 Modulation of Retinal Inflammation Delays Degeneration in a Mouse Model of Geographic Atrophy
Ridley, R. B.; Bowman, B. M.; Lee, J.; Walsh, E.; Massengill, M. T.; Lewin, A. S.; Ildefonso, C. J.
10.1101/2023.02.08.527757 — neuroscience — Posted on 2023-02-09
2745 Spotty distributions: Spotted Gar (Lepisosteus oculatus) and Spotted Sucker (Minytrema melanops) range expansion in eastern Lake Erie
MacGuigan, D. J.; Porto-Hannes, I.; Foote, B.; Backenstose, N. J. C.; Osborne, C.; Louisor, K.; Waterman, H.; Chang, S. L.; Cochran, J. L.; Krabbenhoft, T. J.
10.1101/2023.02.08.527752 — zoology — Posted on 2023-02-09
2746 A Structured Evaluation of Genome-Scale Constraint-Based Modeling Tools for Microbial Consortia
Scott, W. T.; Benito Vaquerizo, S.; Zimmermann, J.; Bajic, D.; Heinken, A.; Suarez-Diez, M.; Schaap, P. J.
10.1101/2023.02.08.527721 — systems biology — Posted on 2023-02-09
2754 TRAF3 Suppression Encourages B Cell Recruitment and Prolongs Survival of Microbiome-Intact Mice with Ovarian Cancer
Zorea, J.; Motro, Y.; Mazor, R.; Carmi, Y.; Shulman, Z.; Mahajna, J.; Moran-Gilad, J.; Elkabets, M.
10.1101/2023.02.09.527814 — cancer biology — Posted on 2023-02-09
2756 Does joint impedance improve dynamic leg simulations with explicit and implicit solvers?
Bahdasariants, S.; Barela, A. M. F.; Gritsenko, V.; Bacca, O.; Barela, J. A.; Yakovenko, S.
10.1101/2023.02.09.527805 — bioinformatics — Posted on 2023-02-09
2759 Enzyme-less nanopore detection of post-translational modifications within long polypeptides
Martin-Baniandres, P.; Lan, W.-H.; Board, S.; Romero-ruiz, M.; Garcia-Manyes, S.; Qing, Y.; Bayley, H.
10.1101/2023.02.09.527483 — biochemistry — Posted on 2023-02-09
2760 A comparative study on the impact of five Desmodium species on soil microbiome reveals enrichment of selected bacterial and fungal taxa
David, A. B.; Mwaikono, K. S.; Midega, C.; Magingo, F.; Alsanius, B. W.; Drinkwater, L. E.; Dekker, T.; Lyantagaye, S.
10.1101/2023.02.07.527423 — ecology — Posted on 2023-02-09
2763 Real-time spectral library matching for sample multiplexed quantitative proteomics.
McGann, C. D.; Barshop, W. D.; Canterbury, J.; Lin, C.; Gabriel, W.; Wilhelm, M.; McAlister, G.; Schweppe, D. K.
10.1101/2023.02.08.527705 — cell biology — Posted on 2023-02-09
2764 Direct observation of a crescent-shape chromosome in Bacillus subtilis
Tisma, M.; Bock, F. P.; Kerssemakers, J.; Japaridze, A.; Gruber, S.; Dekker, C.
10.1101/2023.02.09.527813 — microbiology — Posted on 2023-02-09
2765 Inferring patterns of recombination and divergence with ancient and modern treponemal genomes
Akguel, G.; Pla-Diaz, M.; Molak, M.; du Plessis, L.; Panagiotopoulou, H.; Doan, K.; Bogdanowicz, W.; Oziemblowski, M.; Grzelak, J.; Arora, N.; Gonzalez-Candelas, F.; Majander, K.; Schuenemann, V.
10.1101/2023.02.08.526988 — microbiology — Posted on 2023-02-09
2767 Root associated bacterial communities and root metabolite composition are linked to nitrogen use efficiency in sorghum
Chai, Y. N.; Qi, Y.; Goren, E.; Sheflin, A. M.; Tringe, S.; Prenni, J. E.; Liu, P.; Schachtman, D. P.
10.1101/2023.02.08.527764 — microbiology — Posted on 2023-02-09
2771 Reinforcement-Based Processes Actively Regulate MotorExploration Along Redundant Solution Manifolds
Roth, A. M.; Calalo, J. A.; Lokesh, R.; Sullivan, S. R.; Grill, S.; Jeka, J. J.; van der Kooij, K.; Carter, M. J.; Cashaback, J. G. A.
10.1101/2023.02.08.527668 — neuroscience — Posted on 2023-02-09
2774 Maintenance and transformation of representational formats during working memory prioritization
Estefan, D. P.; Fellner, M. C.; Kunz, L.; Zhang, H.; Reinacher, P.; Roy, C.; Brandt, A.; Schulze-Bonhage, A.; Yang, L.; Wang, S.; Liu, J.; Xue, G.; Axmacher, N.
10.1101/2023.02.08.527513 — neuroscience — Posted on 2023-02-09
2775 Doublecortin-immunoreactive immature neurons in the olfactory system across pregnancy and lactation in female mice
Prina, M.; Esteve-Perez, R.; Navarro-Moreno, C.; Abellan-Alvaro, M.; Lanuza, E.; Sanchez-Catalan, M. J.; Martinez-Garcia, F.; Agustin-Pavon, C.; Torres-Perez, J. V.
10.1101/2023.02.08.527694 — neuroscience — Posted on 2023-02-09
2776 The parabrachial to central amygdala circuit is a key mediator of injury-induced pain sensitization
Torres-Rodriguez, J. M.; Wilson, T. D.; Singh, S.; Chaudhry, S.; Adke, A. P.; Becker, J. J.; Lin, J. L.; Martinez Gonzalez, S.; Soler-Cedeno, O.; Carrasquillo, Y.
10.1101/2023.02.08.527340 — neuroscience — Posted on 2023-02-09
2778 Hippocampal mechanisms support cortisol-induced memory enhancements
Sherman, B. E.; Harris, B. B.; Turk-Browne, N. B.; Sinha, R.; Goldfarb, E. V.
10.1101/2023.02.08.527745 — neuroscience — Posted on 2023-02-09
2780 Breast adipose tissue-derived extracellular vesicles from women with obesity stimulate mitochondrial-induced dysregulated tumor cell metabolism
Liu, S.; Benito-Martin, A.; Vatter, F. A. P.; Hanif, S. Z.; Liu, C.; Bhardwaj, P.; Sethupathy, P.; Farghli, A. R.; Piloco, P.; Paik, P.; Mushannen, M.; Otterburn, D. M.; Cohen, L.; Bareja, R.; Krumsiek, J.; Cohen-Gould, L.; Calto, S.; Spector, J. A.; Elemento, O.; Lyden, D. C.; Brown, K. A.
10.1101/2023.02.08.527715 — cancer biology — Posted on 2023-02-09
2784 Sulfate limitation increases specific pDNA yield in E. coli fed-batch processes
Gotsmy, M.; Stobl, F.; Weiss, F.; Gruber, P.; Kraus, B.; Mairhofer, J.; Zanghellini, J.
10.1101/2023.02.09.527815 — bioengineering — Posted on 2023-02-09
2786 Long-term responses of Icelandic Arctic foxes to changes in marine and terrestrial ecosystems
Berthelot, F. M. L.; Ehrich, D.; Unnsteinsdottir, E. R.; Carbonell Ellgutter, J. A.
10.1101/2023.02.09.527803 — ecology — Posted on 2023-02-09
2791 The Lamin A/C Ig-fold undergoes cell density-dependent changes that alter epitope binding
Wallace, M.; Fedorchak, G. R.; Agrawal, R.; Gilbert, R. M.; Patel, J.; Park, S.; Paszek, M.; Lammerding, J.
10.1101/2022.11.22.517482 — cell biology — Posted on 2023-02-09
2793 Convergent impact of schizophrenia risk genes
Townsley, K. G.; Li, A.; Deans, P. M.; Fullard, J. F.; Yu, A.; Cartwright, S.; Zhang, W.; Wang, M.; Voloudakis, G.; Girdhar, K.; Stahl, E.; Akbarian, S.; Zhang, B.; Roussos, P.; Huckins, L. M.; Brennand, K. J.
10.1101/2022.03.29.486286 — neuroscience — Posted on 2023-02-09
2795 Testing the predictive performance of comparative extinction risk models to support the global amphibian assessment
Lucas, P. M.; Di Marco, M.; Cazalis, V.; Luedtke, J.; Neam, K.; Brown, M. H.; Langhammer, P. F.; Mancini, G.; Santini, L.
10.1101/2023.02.08.526823 — ecology — Posted on 2023-02-08
2797 Mecp2 knock-out astrocytes affect synaptogenesis by IL-6 dependent mechanisms
Albizzati, E.; Florio, E.; Breccia, M.; Cabasino, C.; Pozzi, D.; Boda, E.; Battaglia, C.; De Palma, C.; De Quattro, C.; Landsberger, N.; Frasca, A.
10.1101/2023.02.08.527630 — neuroscience — Posted on 2023-02-08
2799 The microbial community dynamics of cocaine sensitization in two behaviorally divergent strains of collaborative cross mice
Tran, T. D. B.; Hernandez, C. J. M.; Nguyen, H.; Wright, S.; Center for Systems Neurogenetics of Addiction, ; Tarantino, L. M.; Chesler, E. J.; Zhou, Y.; Weinstock, G.; Bubier, J. A.
10.1101/2022.12.06.519360 — animal behavior and cognition — Posted on 2023-02-08
2802 How Occam's razor guides human decision-making
Piasini, E.; Liu, S.; Chaudhari, P.; Balasubramanian, V.; Gold, J. I.
10.1101/2023.01.10.523479 — neuroscience — Posted on 2023-02-08
2803 Paternal methamphetamine exposure induces higher sensitivity to methamphetamine in male offspring through driving ADRB1 on CaMKII-positive neurons in mPFC
Zheng, Y.; Liu, D.; Guo, H.; Chen, W.; Liu, Z.; Li, Z.; Hu, T.; Zhang, Y.; Li, X.; Zhao, Z.; Cai, Q.; Ge, F.; Fan, Y.; Guan, X.
10.1101/2022.08.19.504512 — neuroscience — Posted on 2023-02-08
2804 Metastatic potential in clonal melanoma cells is driven by a rare, early-invading subpopulation
Kaur, A.; Cuenca, L.; Kiani, K.; Busch, G.; Fingerman, D.; Dunagin, M. C.; Li, J.; Dardani, I.; Sanford, E. M.; Pemberton, J.; Goyal, Y.; Weeraratna, A. T.; Herlyn, M.; Raj, A.
10.1101/2022.04.17.488591 — cancer biology — Posted on 2023-02-08
2808 Bioresorbable mesenchymal stem cell-loaded electrospun polymeric scaffold inhibits neointimal hyperplasia following arteriovenous fistula formation in a rat model of chronic kidney disease
Barcena, A. J. R.; Perez, J. V. D.; Bernardino, M.; Damasco, J. A.; Cortes, A.; Del Mundo, H.; San Valentin, E. M. D.; Klusman, C.; Canlas, G.; Heralde, F. M.; Avritscher, R.; Fowlkes, N.; Cheng, J.; Huang, S. Y.; Melancon, M. P.
10.1101/2022.11.21.517369 — bioengineering — Posted on 2023-02-08
2811 Assessing changes in global fire regimes
Sayedi, S. S.; Abbott, B.; Vanniere, B.; Leys, B.; Colombaroli, D.; Gil-Romera, G.; Slowinski, M.; Aleman, J.; Blarquez, O.; Feurdean, A.; Brown, K.; Aakala, T.; Alenius, T.; Allen, K.; Andric, M.; Bergeron, Y.; Biagioni, S.; Bradshaw, R.; Bremond, L.; Brisset, E.; Brooks, J.; Brugger, S.; Brussel, T.; Cadd, H.; Cagliero, E.; Carcaillet, C.; Carter, V.; Catry, F. X.; Champreux, A.; Chaste, E.; Chavardes, R. D.; Chipman, M.; Conedera, M.; Connor, S.; Constantine, M.; Courtney Mustaphi, C.; Dabengwa, A.; Daniels, W.; De Boer, E.; Dietze, E.; Estrany, J.; Fernandes, P.; Finsinger, W.; Flantua, S.
10.1101/2023.02.07.527551 — ecology — Posted on 2023-02-08
2815 The nematode worm C. elegans chooses between bacterial foods as if maximizing economic utility
Katzen, A.; Chung, H.-K.; Harbaugh, W.; Iacono, C. D.; Jackson, N.; Yu, S.; Flavell, S. W.; Glimcher, P.; Andreoni, J.; Lockery, S.
10.1101/2021.04.25.441352 — neuroscience — Posted on 2023-02-08
2816 A Multi-omic and Multi-Species Analysis of Right Ventricular Failure
Mendelson, J. B.; Sternbach, J. D.; Doyle, M. J.; Mills, L.; Hartweck, L. M.; Tollison, W.; Carney, J. P.; Lahti, M. T.; Bianco, R. W.; Kalra, R.; Kazmirczak, F.; Hindmarch, C.; Archer, S. L.; Prins, K. W.; Martin, C. M.
10.1101/2023.02.08.527661 — biochemistry — Posted on 2023-02-08
2819 Ciliary ARL13B inhibits developmental kidney cystogenesis in mouse
Van Sciver, R. E.; Long, A. B.; Katz, H. G.; Gigante, E. D.; Caspary, T.
10.1101/2023.02.08.527739 — developmental biology — Posted on 2023-02-08
2820 A FACT-ETS-1 Antiviral Response Pathway Restricts Viral Replication and is Countered by Poxvirus A51R Proteins
Rex, E. A.; Seo, D.; Chappidi, S.; Pinkham, C.; Brito, S.; Embry, A.; Heisler, D.; Liu, Y.; Luger, K.; Alto, N. M.; da Fonseca, F.; Orchard, R.; Hancks, D.; Gammon, D. B.
10.1101/2023.02.08.527673 — microbiology — Posted on 2023-02-08
2821 Parallel reconstruction of the excitatory and inhibitory inputs received by single neurons reveals the synaptic basis of recurrent spiking
Bartram, J.; Franke, F.; Kumar, S. S.; Buccino, A. P.; Xue, X.; Ganswein, T.; Schroter, M.; Kim, T.; Kasuba, K. C.; Hierlemann, A.
10.1101/2023.01.06.523018 — neuroscience — Posted on 2023-02-08
2830 Conservation management strategy impacts inbreeding and mutation load in scimitar-horned oryx
Humble, E.; Stoffel, M. A.; Dicks, K.; Ball, A. D.; Gooley, R. M.; Chuven, J.; Pusey, R.; al Remeithi, M.; Koepfli, K.-P.; Pukazhenthi, B.; Senn, H.; Ogden, R.
10.1101/2022.06.19.496717 — evolutionary biology — Posted on 2023-02-08
2833 Planarians employ diverse and dynamic stem cell microenvironments to support whole-body regeneration
Benham-Pyle, B. W.; Mann, F. G.; Brewster, C. E.; Dewars, E. R.; Vuu, D. M.; Nowotarski, S. H.; Guerrero-Hernandez, C.; Malloy, S.; Hall, K. E.; Maddera, L. E.; Chen, S.; Morrison, J. A.; McKinney, S. A.; Slaughter, B. D.; Perera, A.; Alvarado, A. S.
10.1101/2022.03.20.485025 — developmental biology — Posted on 2023-02-08
2835 A Non-Canonical IRAK Signaling Pathway Triggered by DNA Damage
Li, Y.; Shah, R. B.; Sarti, S.; Belcher, A. L.; Lee, B. J.; Gorbatenko, A.; Nemati, F.; Yu, I.; Stanley, Z.; Shao, Z.; Silva, J.; Zha, S.; Sidi, S.
10.1101/2023.02.08.527716 — cell biology — Posted on 2023-02-08
2837 The E. coli pathobiont LF82 encodes a unique variant of σ70 that results in specific gene expression changes and altered phenotypes
Arroyo-Mendoza, M.; Proctor, A.; Correa-Medina, A.; Brand, M. W.; Rosas, V.; Wannemuehler, M. J.; Phillips, G. J.; Hinton, D. M.
10.1101/2023.02.08.523653 — molecular biology — Posted on 2023-02-08
2838 Polar Crystal Habit and 3D Electron Diffraction Reveal the Malaria Pigment Hemozoin as a Selective Mixture of Centrosymmetric and Chiral Stereoisomers
Klar, P. B.; Waterman, D.; Gruene, T.; Mullick, D.; Song, Y.; Gilchrist, J. B.; Owen, C. D.; Wen, W.; Biran, I.; Houben, L.; Regev-Rudzki, N.; Dzikowski, R.; Palatinus, L.; Zhang, P.; Leiserowitz, L.; Elbaum, M.
10.1101/2022.09.15.507960 — microbiology — Posted on 2023-02-08
2840 Single cell transcriptomic analysis of renal allograft rejection reveals novel insights into intragraft TCR clonality
Shi, T.; Burg, A. R.; Caldwell, J. T.; Roskin, K.; Rojas, C. M. C.; Chukwuma, P. C.; Gray, G. I.; Foote, S. G.; Alonso, J.; Cuda, C. M.; Allman, D. A.; Rush, J. S.; Regnier, C. H.; Wieczorek, G.; Alloway, R. R.; Shields, A. R.; Baker, B. M.; Woodle, E. S.; Hildeman, D. A.
10.1101/2023.02.08.524808 — immunology — Posted on 2023-02-08
2841 Ts-Biotag, a multimodal reporter of Tie2 expression, labels microglia in a model of neuro injury.
Bartelle, B. B.; Tashi, Z.; Brodsky, J.; Christopher, K. S.; Cerna, G.; Gohsman, S.
10.1101/2023.02.08.527655 — immunology — Posted on 2023-02-08
2842 Early detection of white matter hyperintensities using SHIVA-WMH detector
Tsuchida, A.; Boutinaud, P.; Verrecchia, V.; Tzourio, C.; Debette, S.; Joliot, M.
10.1101/2023.02.03.526961 — neuroscience — Posted on 2023-02-08
2843 NECAB2 participates in an endosomal pathway of mitochondrial stress response at striatal synapses
Bueno, D.; Narayan Dey, P.; Schacht, T.; Wolf, C.; Wüllner, V.; Morpurgo, E.; Rojas-Charry, L.; Sessinghaus, L.; Leukel, P.; Sommer, C.; Radyushkin, K.; Schaefer, M.; Florin, L.; Baumgart, J.; Stamm, P.; Daiber, A.; Horta, G.; Nardi, L.; Vasic, V.; Schmeisser, M. J.; Hellwig, A.; Oskamp, A.; Bauer, A.; Anand, R.; Reichert, A. S.; Ritz, S.; Nocera, G.; Jacob, C.; Peper, J.; Silies, M.; Frauenknecht, K. B. M.; Methner, A.
10.1101/2021.02.15.431234 — neuroscience — Posted on 2023-02-08
2845 Regional vulnerability in a neurodegenerative disease: Delineating SCA1 CNS and muscle therapeutic targets using a conditional mutant ATXN1 mouse
Duvick, L.; Southern, W. M.; Benzow, K.; Handler, H. P.; Mitchell, J. S.; Kuivinen, H.; Gadiparthi, U. K.; Yang, P.; Soles, A.; Scheeler, C.; Rainwater, O.; Serres, S.; Larson, E.; Nichols-Meade, T.; You, Y.; Zoghbi, H. Y.; Ervasti, J. M.; Cvetanovic, M.; Koob, M. D.; Orr, H. T.
10.1101/2023.02.08.527710 — neuroscience — Posted on 2023-02-08
2847 Epilepsy-linked kinase CDKL5 phosphorylates voltage-gated calcium channel Cav2.3, altering inactivation kinetics and neuronal excitability
Sampedro-Castaneda, M.; Baltussen, L. L.; Lopes, A. T.; Qiu, Y.; Sirvio, L.; Mihaylov, S. R.; Claxton, S.; Richardson, J. C.; Lignani, G.; Ultanir, S. K.
10.1101/2022.11.24.517538 — neuroscience — Posted on 2023-02-08
2848 Self-organization, quality control, and preclinical studies of human iPSC-derived retinal sheets for tissue-transplantation therapy
Watari, K.; Yamasaki, S.; Tu, H.-Y.; Shikamura, M.; Kamei, T.; Adachi, H.; Tochitani, T.; Kita, Y.; Nakamura, A.; Ueyama, K.; Ono, K.; Morinaga, C.; Matsuyama, T.; Sho, J.; Nakamura, M.; Fujiwara, M.; Hori, Y.; Tanabe, A.; Hirai, R.; Terai, O.; Ohno, O.; Ohara, H.; Hayama, T.; Ikeda, A.; Nukaya, D.; Matsushita, K.; Takahashi, M.; Kishino, A.; Kimura, T.; Kawamata, S.; Mandai, M.; Kuwahara, A.
10.1101/2022.02.18.480968 — neuroscience — Posted on 2023-02-08
2850 SMRT-AgRenSeq-d in potato (Solanum tuberosum) identifies candidates for the nematode resistance Gpa5
Wang, Y.; Brown, L. H.; Adams, T. M.; Cheung, Y. W.; Li, J.; Young, V.; Todd, D. T.; Armstrong, M. R.; Neugebauer, K.; Kaur, A.; Harrower, B.; Oome, S.; Wang, X.; Bayer, M.; Hein, I.
10.1101/2022.12.08.519582 — plant biology — Posted on 2023-02-08
2851 Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis
Tomic, G.; Sheridan, C.; Refermat, A.; Baggelaar, M.; Sipthorp, J.; Sudarshan, B.; Ocasio, C. A.; Suarez-Bonnet, A.; Priestnall, S.; Herbert, E.; Tate, E.; Downward, J.
10.1101/2023.02.08.527637 — cancer biology — Posted on 2023-02-08
2853 Hypoxia-mediated regulation of DDX5 through decreased chromatin accessibility and post-translational targeting restricts R-loop accumulation
Leszczynska, K. B.; Dzwigonska, M.; Estephan, H.; Moehlenbrink, J.; Bowler, E.; Giaccia, A. J.; Mieczkowski, J.; Kaminska, B.; Hammond, E. M.
10.1101/2022.04.30.490097 — cancer biology — Posted on 2023-02-08
2855 A novel HERC4-dependent glue degrader targeting STING
Mutlu, M.; Schmidt, I.; Morrison, A. I.; Goretzki, B.; Freuler, F.; Begue, D.; Pythoud, N.; Ahrne, E.; Kapps, S.; Roest, S.; Bonenfant, D.; Jeanpierre, D.; Tran, T.-T.-T.; Maher, R.; An, S.; Rietsch, A.; Nigsch, F.; Hofmann, A.; Reece-Hoyes, J.; Parker, C. N.; Guerini, D.
10.1101/2023.02.08.527642 — molecular biology — Posted on 2023-02-08
2857 Comparative proteomics of vesicles essential for the egress of Plasmodium falciparum gametocytes from red blood cells
Sassmannshausen, J.; Bennink, S.; Distler, U.; Küchenhoff, J.; Minns, A. M.; Lindner, S. E.; Burda, P.-C.; Tenzer, S.; Gilberger, T. W.; Pradel, G.
10.1101/2023.02.08.527640 — molecular biology — Posted on 2023-02-08
2862 Influenza virus transcription and progeny production are poorly correlated in single cells
Bacsik, D. J.; Dadonaite, B.; Butler, A.; Greaney, A. J.; Heaton, N. S.; Bloom, J. D.
10.1101/2022.08.30.505828 — microbiology — Posted on 2023-02-08
2863 ENGRAILED-1 transcription factor exerts a paracrine neurotrophic activity on adult spinal cord α-motoneurons.
Leboeuf, M.; Vargas-Abonce, S. E.; Peze-Hedsieck, E.; Dupont, E.; Jimenez-Alonso, L.; MOYA, K. L.; Prochiantz, A.
10.1101/2022.08.16.504081 — neuroscience — Posted on 2023-02-08
2868 Targeting the cell and non-cell autonomous regulation of 47S synthesis by GCN2 in colon cancer.
Piecyk, M.; Triki, M.; Laval, P.-A.; Duret, C.; Fauvre, J.; Cussonneau, L.; Machon, C.; Guitton, J.; Rama, N.; Gibert, B.; Ichim, G.; Catez, F.; Bourdelais, F.; Durand, S.; Diaz, J.-J.; Coste, I.; Renno, T.; Serge, M.; Nicolas, A.; Ansieau, S.; Ferraro-Peyret, C.; Chaveroux, C.
10.1101/2023.02.08.527626 — cancer biology — Posted on 2023-02-08
2869 Genetic investigation of honeybee populations in Kazakhstan
Gritsenko, D.; Temirbayeva, K.; Taskuzhina, A.; Kostyukova, V.; Pozharskiy, A.; Khusnitdinova, M.; Krupskiy, O.; Mayer, A.; Nuralieva, U.; Bienefeld, K.
10.1101/2023.02.08.527617 — genetics — Posted on 2023-02-08
2872 Structural stability of the oyster gut microbiome contributes to the host's physiological tolerance to temperature fluctuations on tropical rocky shores
Arromrak, B. S.; Wong, A. T. C.; Hui, T. Y.; Leung, K. S.; Williams, G. A.; Ganmanee, M.; Durand, T.; Lee, J. C. Y.; Gaitan-Espitia, J. D.
10.1101/2023.02.08.527599 — microbiology — Posted on 2023-02-08
2873 A simple mechanism for integration of quorum sensing and cAMP signalling in V. cholerae
Walker, L.; Haycocks, J. R.; van Kessel, J.; Dalia, T. N.; Dalia, A. B.; Grainger, D. C.
10.1101/2023.02.08.527633 — microbiology — Posted on 2023-02-08
2877 Increased endothelium activation and leakage do not promote diastolic dysfunction in mice fed with a high fat diet and treated with L-NAME
Cornuault, L.; Mora, P.; Rouault, P.; Foussard, N.; Chapouly, C.; Alzieu, P.; Gadeau, A.-P.; Couffinhal, T.; Renault, M.-A.
10.1101/2023.02.08.527684 — pathology — Posted on 2023-02-08
2878 MiR-4521 perturbs FOXM1-mediated DNA damage response in breast cancer
Kuthethur, R.; Adiga, D.; Kandettu, A.; Jerome, M. S.; Mallya, S.; Mumbrekar, K. D.; Kabekkodu, S. P.; Chakrabarty, S.
10.1101/2023.02.08.527613 — cancer biology — Posted on 2023-02-08
2880 Sex-specific declines in cholinergic-targeting tRNA fragments in the nucleus accumbens in Alzheimer's disease
Shulman, D.; Dubnov, S.; Zorbaz, T.; Madrer, N.; Paldor, I.; Bennett, D. A.; Seshadri, S.; Mufson, E. J.; Greenberg, D.; Loewenstein, Y.; Soreq, H. S.
10.1101/2023.02.08.527612 — bioinformatics — Posted on 2023-02-08
2883 Shear-Mediated Platelet Microparticles Demonstrate Phenotypic Heterogeneity as to Morphology, Receptor Distribution, and Hemostatic Function
Roka-Moiia, Y.; Ammann, K. R.; Miller-Gutierrez, S.; Sheriff, J.; Bluestein, D.; Italiano, J. E.; Flaumenhaft, R.; Slepian, M. J.
10.1101/2023.02.08.527675 — biochemistry — Posted on 2023-02-08
2885 Ev-OSMOSE: An eco-genetic marine ecosystem model
Morell, A.; Shin, Y.-J.; Barrier, N.; Travers-Trolet, M.; Ernande, B.
10.1101/2023.02.08.527669 — ecology — Posted on 2023-02-08
2886 Enhancer-promoter interactions are reconfigured through the formation of long-range multiway chromatin hubs as mouse ES cells exit pluripotency
Lando, D.; Ma, X.; Cao, Y.; Jartseva, A.; Stevens, T. J.; Boucher, W.; Reynolds, N.; Montibus, B.; Hall, D.; Lackner, A.; Ragheb, R.; Leeb, M.; Hendrich, B.; Laue, E. D.
10.1101/2023.02.08.527615 — developmental biology — Posted on 2023-02-08
2887 Catalytic antibodies in arrhythmogenic cardiomyopathy patients cleave desmoglein 2 and N-cadherin and impair cardiomyocyte cohesion
Yeruva, S.; Stangner, K.; Jungwirth, A.; Hiermaier, M.; Shoykhet, M.; Kugelmann, D.; Hertl, M.; Egami, S.; Ishii, N.; Koga, H.; Hashimoto, T.; Weis, M.; Beckmann, B. M.; Biller, R.; Schuettler, D.; Kaab, S.; Waschke, J.
10.1101/2023.02.08.527624 — cell biology — Posted on 2023-02-08
2888 Gut microbes predominantly act as symbiotic partners rather than raw nutrients
da Silva Soares, N. F.; Quagliariello, A.; Yigitturk, S.; Martino, M. E.
10.1101/2023.02.08.527620 — microbiology — Posted on 2023-02-08
2890 Metabolization of alpha-D-carba-glucosamine in vivo generates antimetabolites of cell wall precursors
Mund, M.; Friz, S.; Esser, A.; Matzner, D.; Babczyk, B.; Menche, D.; Broetz-Oesterhelt, H.; Mayer, C.; Mayer, G.
10.1101/2023.02.08.527593 — microbiology — Posted on 2023-02-08
2891 Geography and environmental pressure are predictive of class-specific 1 radioresistance in black fungi
Aureli, L.; COLEINE, C.; DELGADO BAQUERIZO, M.; Ahren, D.; Cemmi, A.; Di Sarcina, I.; Onofri, S.; Selbmann, L.
10.1101/2023.02.08.527471 — microbiology — Posted on 2023-02-08
2894 Surf4 deficiency reduces intestinal lipid absorption and secretion and decreases metabolism in mice
Tao, G.; Wang, H.; Shen, Y.; Zhai, L.; Liu, B.; Wang, B.; Chen, W.; Xing, S.; Chen, Y.; Gu, H.-m.; Qin, S.; Zhang, D.-w.
10.1101/2023.02.08.527677 — physiology — Posted on 2023-02-08
2895 An Unexpected Role of Neutrophils in Clearing Apoptotic Hepatocytes In Vivo
Cao, L.; Ma, L.; Zhao, J.; Wang, X.; Fang, X.; Li, W.; Qi, Y.; Tang, Y.; Liu, J.; Peng, S.; Yang, L.; Zhou, L.; Li, L.; Hu, X.; Ji, Y.; Hou, Y.; Zhao, Y.; Zhang, X.; Zhao, Y.; Zhao, Y.; Wei, Y.; Malik, A.; Saiyin, H.; Xu, J.
10.1101/2023.02.08.527616 — physiology — Posted on 2023-02-08
2897 Mass spectrometric analysis and biostimulatory effects of boar seminal gel, saliva and semen in pigs
Kumar, S.; Islam, R.; Chanda, A.; Das, P. J.; Banik, S.; Barman, K.; Pegu, S. R.; Rajkhowa, S.; Gupta, V. K.
10.1101/2023.02.08.527243 — animal behavior and cognition — Posted on 2023-02-08
2898 At the core of salinity: convergent and divergent transcriptome response pathways to neutral and alkaline salinity in natural populations of Arabidopsis thaliana
Almira-Casellas, M. J.; Busoms, S.; Perez-Martin, L.; Escola, G.; Lopez-Valinas, A.; Garcia-Molina, A.; Llugany, M.; Poschenrieder, C.
10.1101/2023.02.05.527167 — molecular biology — Posted on 2023-02-08
2901 The Alfin-like transcription factor GmAlfin09 regulates endoplasmic reticulum stress in soybean via a peroxidase GmPRDX6
Chen, K.; Guo, D.; Yan, J.; Zhang, H.; He, Z.; Wang, C.; Tang, W.; Zhou, Y.; Chen, J.; Xu, Z.-S.; Ma, Y.; Chen, M.
10.1101/2023.02.05.527234 — plant biology — Posted on 2023-02-08
2903 SorCS2 binds progranulin and regulates motor axon outgrowth
Thomassen, P. B.; Salasova, A.; Login, H.; Beel, S.; Tranberg-Jensen, J.; Qvist, P.; Ovesen, P. L.; Nolte, S.; Nejsum, L.; Chao, M. V.; Dasen, J.; Van Damme, P.; Sorensen, K. K.; Oxvig, C.; Nykjaer, A.
10.1101/2023.02.08.527602 — developmental biology — Posted on 2023-02-08
2904 Discovery of the gut microbial enzyme responsible for bilirubin reduction to urobilinogen
Hall, B.; Levy, S.; Default-Tompson, K.; Minabou, G.; Weiss, A.; Braccia, D.; Jenkins, C.; Yang, Y.; Arp, G.; Abeysinghe, S.; Jermain, M.; Wu, D.; Jiang, X.
10.1101/2023.02.07.527579 — microbiology — Posted on 2023-02-08
2905 Glycosylated extracellular mucin domains protect against SARS CoV-2 infection at the respiratory surface
Chatterjee, M.; Huang, L. Z. X.; Mykytyn, A. Z.; Wang, C.; Lamers, M. M.; Westendorp, B.; Wubbolts, R. W.; Putten, J. P. M. v.; Bosch, B. J.; Haagmans, B.; Strijbis, K.
10.1101/2021.10.29.466408 — microbiology — Posted on 2023-02-08
2908 Photobiomodulation Therapy for a Novel Olfactory Dysfunction Ischemic Stroke Model
Shalaby, R. A.; Qureshi, M. M.; Khan, M. A.; Salam, S. M. A.; Kwon, H. S.; Lee, K. H.; Chung, E.; Kim, Y. R.
10.1101/2023.02.07.527573 — neuroscience — Posted on 2023-02-08
2912 Cerebral Topographies of Perceived and Felt Emotions
Saarimaki, H.; Nummenmaa, L.; Volynets, S.; Santavirta, S.; Aksiuto, A.; Sams, M.; Jaaskelainen, I. P.; Lahnakoski, J.
10.1101/2023.02.08.521183 — neuroscience — Posted on 2023-02-08
2914 Junctophilin-2 Regulates Mitochondrial Metabolism
Prisco, S.; Hartweck, L. M.; Kazmirczak, F.; Mendelson, J. B.; Deng, S. L.; Lahiri, S. K.; Wehrens, X.; Prins, K.
10.1101/2023.02.07.527576 — physiology — Posted on 2023-02-08
2918 Extending the dynamic range of biomarker quantification through molecular equalization
Newman, S. S.; Wilson, B.; Mamerow, D.; Wollant, B.; Nyein, H.; Rosenberg-Hasson, Y.; Maecker, H.; Eisenstein, M.; Soh, H. T.
10.1101/2023.02.07.527534 — bioengineering — Posted on 2023-02-08
2921 Assessing changes in global fire regimes
Sayedi, S. S.; Global group of fire experts,
10.1101/2023.02.07.527551 — ecology — Posted on 2023-02-08
2922 Toxic metal uptake by oyster mushrooms grown in sugarcane bagasse
Saha, T.; Das, S.; Sau, S.; Datta, D.; Kundu, S.; Saha, S.; Chakraborty, S.; Mitra, A. K.
10.1101/2023.02.07.523865 — ecology — Posted on 2023-02-08
2926 BAF chromatin complexes do not mediate GLI transcriptional repression of Hedgehog target genes
Ramachandran, J.; Chen, W.; Lex, R. K.; Windsor, K.; Lee, H.; Wang, T.; Zhou, W.; Ji, H.; Vokes, S. A.
10.1101/2023.02.03.527038 — developmental biology — Posted on 2023-02-08
2928 Human FAM111A inhibits vaccinia virus replication by degrading viral DNA-binding protein I3 and is antagonized by poxvirus host range factor SPI-1
Zhu, J.; Gao, X.; Zhang, Z.; Deng, Y.; Xie, S.; Ren, S.; Li, Y.; Li, H.; Niu, K.; Fu, S.; Li, Y.; Moss, B.; Wu, W.; Peng, C.
10.1101/2023.02.04.527148 — microbiology — Posted on 2023-02-08
2930 Should bionic limb control mimic the human body? Impact of control strategy on bionic hand skill learning
Schone, H. R.; Udeozor, M.; Moninghoff, M.; Rispoli, B.; Vandersea, J.; Lock, B.; Hargrove, L.; Makin, T. R.; Baker, C. I.
10.1101/2023.02.07.525548 — neuroscience — Posted on 2023-02-08
2932 Subdural CMOS optical probe (SCOPe) for bidirectional neural interfacing
Pollmann, E. H.; Yin, H.; Uguz, I.; Dubey, A.; Wingel, K. E.; Choi, J. S.; Moazeni, S.; Gilhotra, Y.; Pavlovsky, V. A.; Banees, A. A.; Boominathan, V.; Robinson, J.; Veeraraghavan, A.; Pieribone, V. A.; Pesaran, B.; Shepard, K. L.
10.1101/2023.02.07.527500 — neuroscience — Posted on 2023-02-08
2933 Disentangling the neurobiological bases of temporal impulsivity in Huntington's disease
Pardina-Torner, H.; De Paepe, A. E.; Garcia-Gorro, C.; Rodriguez-Dechicha, N.; Calopa, M.; Ruiz-Idiago, J.; Mareca, C.; de Diego-Balaguer, R.; Camara, E.
10.1101/2023.02.07.527472 — neuroscience — Posted on 2023-02-08
2934 Peer's Presence Reverses Escalated Cocaine Intake In Rats
Vielle, C.; Tiran-Cappello, A.; Vignal, L.; Maurice, N.; Degoulet, M.; Brocard, C.; Pelletier, F.; Pelloux, Y.; Baunez, C.
10.1101/2023.02.07.527550 — neuroscience — Posted on 2023-02-08
2937 MGA deletion leads to Richter's transformation via modulation of mitochondrial OXPHOS
Iyer, P.; Zhang, B.; Liu, T.; Jin, M.; Hart, K.; Zhang, J.; Song, J.; Chan, W. C.; Siddiqi, T.; Rosen, S. T.; Danilov, A.; Wang, L.
10.1101/2023.02.07.527502 — cancer biology — Posted on 2023-02-08
2938 Colocalization of Cancer Associated Biomarkers on Single Extracellular Vesicles for Early Cancer Detection
Salem, D. P.; Bortolin, L. T.; Couvillon, A. D.; Gusenleitner, D.; Grosha, J.; Zabrowski, I. O.; Biette, K. M.; Banerjee, S.; Sedlak, C. R.; Byrne, D. M.; Hamzeh, B. F.; King, M. S.; Cuoco, L. T.; Duff, P. A.; Winn-Deen, E. S.; Huang, E. K.; Schekman, R.; Sedlak, J. C.
10.1101/2023.02.07.527360 — cancer biology — Posted on 2023-02-08
2941 Plant spectral diversity from high-resolution multispectral imagery detects functional diversity patterns in coastal dune communities.
Beccari, E.; P. Carmona, C.; Tordoni, E.; Petruzzellis, F.; Martinucci, D.; Casagrande, G.; Pavanetto, N.; Rocchini, D.; D'Antraccoli, M.; Ciccarelli, D.; Bacaro, G.
10.1101/2023.02.07.527269 — ecology — Posted on 2023-02-08
2944 Avirulent ME49Δgra5 Protecting Hosts Against Toxoplasma gondii Infection and Breast Tumors
Chen, M.; Yang, P.; Xin, Z.; Chen, J.; Zou, W.; Zhou, L.; Yang, L.; Peng, J.; Peng, H.-J.
10.1101/2023.02.07.527439 — microbiology — Posted on 2023-02-08
2945 Dissemination of IncI plasmid encoding blaCTX-M-1 is not hampered by its fitness cost in the pig's gut.
Allain, M.; Maherault, A.-C.; Gachet, B.; Martinez, C.; Condamine, B.; Magnan, M.; Kempf, I.; Denamur, E.; Landraud, L.
10.1101/2023.02.03.527097 — microbiology — Posted on 2023-02-08
2950 A Novel Single Vector Intersectional AAV Strategy for Interrogating Cellular Diversity and Brain Function
Hughes, A. C.; Pollard, B. G.; Xu, B.; Gammons, J. W.; Chapman, P.; Bikoff, J. B.; Schwarz, L. A.
10.1101/2023.02.07.527312 — neuroscience — Posted on 2023-02-08
2951 Sharp wave ripple coupling in zebrafish hippocampus and basolateral amygdala
Blanco, I.; Caccavano, A.; Wu, J. Y.; Vicini, S.; Glasgow, E.; Conant, K.
10.1101/2023.02.07.527487 — neuroscience — Posted on 2023-02-08
2953 IQGAP2 regulates blood-brain barrier immune dynamics
Katdare, K.; Kjar, A.; O'Brown, N.; Neal, E.; Sorets, A.; Shostak, A.; Mlouk, K.; Kim, H.; Horner, K.; Schrag, M.; Megason, S.; Lippmann, E.
10.1101/2023.02.07.527394 — neuroscience — Posted on 2023-02-08
2955 Human dorsal root ganglia after plexus injury: either preservation or loss of the multicellular unit
Schulte, A.; Degenbeck, J.; Aue, A.; Schindehuette, M.; Schlott, F.; Schneider, M.; Monoranu, C. M.; Bohnert, M.; Pham, M.; Antoniadis, G.; Blum, R.; Rittner, H. L.
10.1101/2023.02.06.526934 — neuroscience — Posted on 2023-02-08
2956 Systematic comparison of risky choices in humans and monkeys
Seak, L. C. U.; Ferrari-Toniolo, S.; Jain, R.; Nielsen, K.; Schultz, W.
10.1101/2023.02.07.527517 — neuroscience — Posted on 2023-02-08
2957 RxRx3: Phenomics Map of Biology
Fay, M. M.; Kraus, O.; Victors, M.; Arumugam, L.; Vuggumudi, K.; Urbanik, J.; Hansen, K.; Celik, S.; Cernek, N.; Jagannathan, G.; Christensen, J.; Earnshaw, B. A.; Haque, I. S.; Mabey, B.
10.1101/2023.02.07.527350 — systems biology — Posted on 2023-02-08
2963 Rigosertib promotes anti-tumor immunity via autophagic degradation of PD-L1 in colorectal cancer cells
Zhou, X.; Fu, D.; Yang, H.; Le, C.; Lu, Y.; Wei, J.; Tang, Y.; Zhang, J.; Yuan, Y.; Ding, K.; Xiao, Q.
10.1101/2023.02.07.527284 — cancer biology — Posted on 2023-02-08
2965 Fast and artifact-free excitation multiplexing using synchronized image scanning
Bruggeman, E.; Van den Eynde, R.; Amouroux, B.; Venneman, T.; Vanden Berghe, P.; Muller, M.; Vandenberg, W.; Dedecker, P.
10.1101/2023.02.07.527342 — biophysics — Posted on 2023-02-08
2967 A General Fluorescence-Based Method for Quantifying and Mapping Biomolecular Polarity In Vitro and In Cells
Owyong, T. C.; O'Shea, R.; Lee, M.; White, J. M.; Donnelly, P. S.; Hinde, E.; Wong, W. W. H.; Hong, Y.
10.1101/2023.02.07.526546 — biochemistry — Posted on 2023-02-08
2970 Mechanisms of spinophilin-dependent pancreas dysregulation underlying diabesity
Stickel, K. C.; Mosley, A. L.; Doud, E. H.; Belecky-Adams, T. L.; Baucum, A. J.
10.1101/2023.02.07.527495 — cell biology — Posted on 2023-02-08
2972 Odor imagery but not perception drives risk for food cue reactivity and increased adiposity
Perszyk, E. E.; Davis, X. S.; Djordjevic, J.; Jones-Gotman, M.; Trinh, J.; Hutelin, Z.; Veldhuizen, M. G.; Koban, L.; Wager, T. D.; Kober, H.; Small, D. M.
10.1101/2023.02.06.527292 — neuroscience — Posted on 2023-02-08
2976 POLCAM: Instant molecular orientation microscopy for the life sciences
Bruggeman, E.; Zhang, O.; Needham, L.-M.; Koerbel, M.; Daly, S.; Cheetham, M.; Peters, R.; Wu, T.; Klymchenko, A. S.; Davis, S. J.; Paluch, E. K.; Klenerman, D.; Lew, M. D.; O'Holleran, K.; Lee, S. F.
10.1101/2023.02.07.527479 — biophysics — Posted on 2023-02-08
2981 Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury
Mohr, M. E.; Li, S.; Trouten, A. M.; Stairley, R. A.; Roddy, P. L.; Liu, C.; Zhang, M.; Sucov, H.; TAO, G.
10.1101/2023.02.07.527364 — cell biology — Posted on 2023-02-08
2982 CD38 promotes hematopoietic stem cell dormancy via c-Fos
Ibneeva, L.; Singh, S. P.; Sinha, A.; Eski, S. E.; Wehner, R.; Rupp, L.; Perez-Valencia, J. A.; Gerbaulet, A.; Reinhardt, S.; Wobus, M.; Bonin, M.; Sancho, J.; Lund, F. E.; Dahl, A.; Schmitz, M.; Bornhaeuser, M.; Chavakis, T.; Wielockx, B.; Grinenko, T.
10.1101/2023.02.08.527614 — cell biology — Posted on 2023-02-08
2984 Ferroptosis is determined by chloride ions
Huang, D.; Dai, Z.; Wang, C.; Mai, H.; Zhao, J.; Cao, L.; Wang, S.; Dai, Z.; Xu, K.; He, R.; Zhu, S.; Chen, Y.; Bing, T.; Zhu, X.; Chew, T. G.; Huang, J.
10.1101/2023.02.07.526847 — cell biology — Posted on 2023-02-08
2985 Dynamic mapping of proteome trafficking within and between living cells by TransitID
Qin, W.; Cheah, J. S.; Xu, C.; Messing, J.; Freibaum, B. D.; Boeynaems, S.; Taylor, J. P.; Udeshi, N. D.; Carr, S. A.; Ting, A. Y.
10.1101/2023.02.07.527548 — cell biology — Posted on 2023-02-08
2991 Unlocking de novo antibody design with generative artificial intelligence
Shanehsazzadeh, A.; Bachas, S.; Kasun, G.; Sutton, J. M.; Steiger, A. K.; Shuai, R.; Kohnert, C.; Morehead, A.; Brown, A.; Chung, C.; Luton, B. K.; Diaz, N.; McPartlon, M.; Knight, B.; Radach, M.; Bateman, K.; Spencer, D. A.; Cejovic, J.; Kopec-Belliveau, G.; Haile, R.; Yassine, E.; McCloskey, C.; Natividad, M.; Chapman, D.; Stojanovic, L.; Rakocevic, G.; Yapici, E.; Moran, K.; Caguiat, R.; Abdulhaqq, S.; Guo, Z.; Klug, L. R.; Gander, M.; Meier, J.
10.1101/2023.01.08.523187 — synthetic biology — Posted on 2023-02-08
2993 Planarians employ diverse and dynamic stem cell microenvironments to support whole-body regeneration
Benham-Pyle, B. W.; Mann, F. G.; Brewster, C. E.; Dewars, E. R.; Nowotarski, S. H.; Guerrero-Hernandez, C.; Malloy, S.; Hall, K. E.; Maddera, L. E.; Chen, S.; Morrison, J. A.; Slaughter, B. D.; Perera, A.; Alvarado, A. S.
10.1101/2022.03.20.485025 — developmental biology — Posted on 2023-02-08
2994 Simultaneous profiling of spatial gene expression and chromatin accessibility for mouse brain development
Peng, G.; Jiang, F.; Zhou, X.; Qian, Y.; Wang, L.; Shen, Q.; Qu, F.; Cui, G.; Chen, K.; Li, Z.; Zhu, M.
10.1101/2022.03.22.485333 — developmental biology — Posted on 2023-02-08
2995 Global and cell type-specific immunological hallmarks of severe dengue progression
Ghita, L.; Yao, Z.; Xie, Y.; Duran, V.; Cagirici, B. H.; Samir, J.; Osman, I.; Agudelo, O. L.; Sanz, A. M.; Sahoo, M. K.; Robinson, M.; Gelvez, R. M.; Bueno, N.; Luciani, F.; Pinsky, B. A.; Montoya, J. G.; Estupinan Cardenas, M. I.; Villar, L. A.; Rojas Garrido, E. M.; Rosso, F.; Quake, S. R.; Zanini, F.; Einav, S.
10.1101/2022.12.11.519930 — immunology — Posted on 2023-02-08
2997 WNT activity reveals context-specific genetic effects on gene regulation in neural progenitors
Matoba, N.; Le, B. D.; Valone, J. M.; Wolter, J. M.; Mory, J.; Liang, D.; Aygun, N.; Broadaway, K. A.; Bond, M. L.; Mohlke, K. L.; Zylka, M. J.; Love, M. I.; Stein, J. L.
10.1101/2023.02.07.527357 — genetics — Posted on 2023-02-07
3005 Mitochondrial metabolism in primary and metastatic human kidney cancers
Bezwada, D.; DeBerardinis, R. J.; Lesner, N. P.; Brooks, B.; Vu, H. S.; Wu, Z.; Cai, L.; Kasitinon, S.; Kelekar, S.; Cai, F.; Aurora, A. B.; Patrick, M.; Leach, A.; Ghandour, R.; Zhang, Y.; Do, D.; Sudderth, J.; Dumesnil, D.; House, S.; Rosales, T.; Poole, A. M.; Lotan, Y.; Woldu, S.; Bagrodia, A.; Meng, X.; Cadeddu, J. A.; Mishra, P.; Pedrosa, I.; Kapur, P.; Courtney, K. D.; Malloy, C. R.; Margulis, V.
10.1101/2023.02.06.527285 — cancer biology — Posted on 2023-02-07
3007 Digital data storage on DNA tape using CRISPR base editors
Sadremomtaz, A.; Glass, R. F.; Guerrero, J. E.; LaJeunesse, D. R.; Josephs, E. A.; Zadegan, R.
10.1101/2023.02.07.527074 — bioengineering — Posted on 2023-02-07
3008 Development and optimisation of cationic lipid nanoparticles for mRNA delivery
Yan, D.; Lu, H.; Bhamra, A. K.; Fu, R.; Wang, N.; Teh, J. H.; Lou, H.; Chen, R.; Aboagye, E. O.
10.1101/2023.02.07.524134 — bioengineering — Posted on 2023-02-07
3010 Full-length isoform sequencing for resolving the molecular basis of Charcot-Marie-Tooth 2A
Stergachis, A. B.; Blue, E. E.; Gillentine, M. A.; Wang, L.-k.; Schwarze, U.; Sedeno Cortes, A.; Ranchalis, J.; Allworth, A.; Bland, A. E.; Chanprasert, S.; Chen, J.; Doherty, D.; Folta, A. B.; Glass, I.; Horike-Pyne, M.; Huang, A. Y.; Khan, A. T.; Leppig, K. A.; Miller, D. E.; Mirzaa, G.; Parhin, A.; Raskind, W.; Rosenthal, E. A.; Sheppeard, S.; Strohbehn, S.; Sybert, V. P.; Tran, T. T.; Wener, M.; Byers, P. H.; Nelson, S. F.; Bamshad, M. J.; Dipple, K. M.; Jarvik, G. P.; Hoppins, S.; Hisama, F. M.
10.1101/2023.02.07.526487 — genetics — Posted on 2023-02-07
3012 A PARP inhibitor, rucaparib, improves cardiac dysfunction in ADP-ribose-acceptor hydrolase 3 (Arh3) deficiency
Yamashita, S.; Bu, X.; Ishiwata-Endo, H.; Kato, J.; Springer, D.; Noguchi, A.; Peiravi, M.; Liu, C.; Zhang, F.; Yu, Z.-X.; Clevenger, R.; Keeran, K.; San, H.; Lizak, M. J.; Moss, J.
10.1101/2023.02.07.527369 — molecular biology — Posted on 2023-02-07
3013 IVT generation of guideRNAs for Cas9-enrichment Nanopore Sequencing
Gilpatrick, T.; Wang, J. Z.; Weiss, D.; Norris, A. L.; Eshleman, J. R.; Timp, W.
10.1101/2023.02.07.527484 — molecular biology — Posted on 2023-02-07
3017 Dynamic Periodicity of Extended-Spectrum Cephalosporin Resistant Bloodstream Escherichia coli Infections Driven by Non-CC131 Strains
Shropshire, W. C.; Strope, B.; Selvaraj Anand, S.; Bremer, J.; McDaneld, P.; Bhatti, M. M.; Flores, A. R.; Kalia, A.; Shelburne, S. A.
10.1101/2023.02.07.527510 — microbiology — Posted on 2023-02-07
3018 Transmissibility of clinically relevant atovaquone-resistant Plasmodium falciparum by anopheline mosquitoes
Balta, V. A.; Stiffler, D.; Sayeed, A.; Tripathi, A. K.; Elahi, R.; Mlambo, G.; Bakshi, R. P.; Dziedzic, A. G.; Jedlicka, A. E.; Nenortas, E.; Romero-Rodriguez, K.; Canonizado, M. A.; Mann, A.; Owen, A.; Sullivan, D. J.; Prigge, S. T.; Sinnis, P.; Shapiro, T. A.
10.1101/2023.02.07.527535 — microbiology — Posted on 2023-02-07
3020 Neutralization of SARS-CoV-2 BQ.1.1 and XBB.1.5 by Breakthrough Infection Sera from Previous and Current Waves in China
Wang, X.; Jiang, S.; Jiang, S.; Li, X.; Ai, J.; Lin, K.; Lv, S.; Zhang, S.; Li, M.; He, X.; Li, D.; Li, C.; Zhao, C.; Zhao, X.; Qiao, R.; Cui, Y.; Chen, Y.; Li, J.; Cai, G.; Li, J.; Dai, L.; Hu, Z.; Zhang, W.; Zhang, Y.; Wang, P.
10.1101/2023.02.07.527406 — immunology — Posted on 2023-02-07
3021 Emergence and suppressive function of Tr1 cells in glomerulonephritis
Soukou-Wargalla, S.; Kilian, C.; Velasquez, L.; Machicote, A.; Stumme, F.; Bedke, T.; Giannou, A.; Kempski, J.; Sabihi, M.; Song, N.; Paust, H.-J.; Borchers, A.; Perez, L. G.; Pelczar, P.; Liu, B.; Ergen, C.; Steglich, B.; Muscate, F.; Huber, T. B.; Panzer, U.; Gagliani, N.; Krebs, C. F.; Huber, S.
10.1101/2023.02.07.527417 — immunology — Posted on 2023-02-07
3023 mRNA trans-splicing dual AAV vectors for (epi)genome editing and gene therapy
Riedmayr, L. M.; Hinrichsmeyer, K. S.; Thalhammer, S. B.; Karguth, N.; Boehm, S.; Mittas, D. M.; Weber, V. J.; Otify, D.; Splith, V.; Bruemmer, M.; Boon, N.; Wijnholds, J.; Mehlfeld, V.; Michalakis, S.; Fenske, S.; Biel, M.; Becirovic, E.
10.1101/2023.02.07.527504 — bioengineering — Posted on 2023-02-07
3025 Host genetics and COVID-19 severity: increasing the accuracy of latest severity scores by Boolean quantum features
Martelloni, G.; Turchi, A.; Fallerini, C.; Degl'Innocenti, A.; Baldassarri, M.; GEN-COVID Multicenter study, ; Olmi, S.; Furini, S.; Renieri, A.
10.1101/2023.02.06.527291 — genomics — Posted on 2023-02-07
3028 Faecal carriage of ESBL-producing Escherichia coli in a remote region of Niger
Jacquier, H.; Assao, B.; Chau, F.; Guindo, O.; Condamine, B.; Magnan, M.; Bridier-Nahmias, A.; Sayingoza-Makombe, N.; Moumouni, A.; Page, A.-L.; Langendorf, C.; Coldiron, M.; Denamur, E.; de Lastours, V.
10.1101/2022.07.07.499258 — microbiology — Posted on 2023-02-07
3029 Hospital and urban wastewaters shape the structure and active resistome of environmental biofilms
Buelow, E.; Dauga, C.; Carrion, C.; Mathe-Hubert, H.; Achaibou, S.; Gaschet, M.; Jove, T.; Chesneau, O.; Kennedy, S. P.; Ploy, M.-C.; Da Re, S.; DAGOT, C.
10.1101/2023.01.19.524754 — microbiology — Posted on 2023-02-07
3030 Dogs and cats are less susceptible to the omicron variant of concern of SARS-CoV-2 - a field study
Klein, C.; Michelitsch, A.; Allendorf, V.; Conraths, F. J.; Beer, M.; Denzin, N.; Wernike, K.
10.1101/2023.02.07.527419 — microbiology — Posted on 2023-02-07
3032 Acetate supplementation rescues social deficits and alters transcriptional regulation in prefrontal cortex of Shank3 deficient mice
Osman, A.; Mervosh, N. L.; Strat, A. N.; Euston, T. J.; Zipursky, G. D.; Pollak, R. M.; Meckel, K. R.; Tyler, S. R.; Chan, K. L.; Buxbaum Grice, A.; Drapeau, E.; Litichevskiy, L.; Gill, J.; Thaiss, C. A.; Buxbaum, J.; Breen, M. S.; Kiraly, D. D.
10.1101/2020.04.29.065821 — neuroscience — Posted on 2023-02-07
3034 MPK12 in stomatal CO2 signaling: function beyond its kinase activity
Yeh, C. -Y.; Wang, Y.-S.; Takahashi, Y.; Kuusk, K.; Paul, K.; Arjus, T.; Yadlos, O.; Schroeder, J. I.; Ilves, I.; Garcia-Sosa, A. T.; Kollist, H.
10.1101/2023.01.31.526436 — plant biology — Posted on 2023-02-07
3035 Dynamics of mRNA fate during light stress and recovery: from transcription to stability and translation
Smith, A. B.; Ganguly, D. R.; Moore, M.; Bowerman, A. F.; Janapala, Y.; Shirokikh, N.; Pogson, B. J.; Crisp, P. A.
10.1101/2022.06.10.495589 — plant biology — Posted on 2023-02-07
3038 The Symmetry and Asymmetry Behind Histone Folding Across Eukarya and Archaea
Zhao, H.; Wu, H.; Guseman, A.; Abeykoon, D.; Camara, C. M.; Dalal, Y.; Fushman, D.; Papoian, G.
10.1101/2022.10.15.512373 — biophysics — Posted on 2023-02-07
3039 From contigs towards chromosomes: automatic Improvement of Long Read Assemblies (ILRA)
Ruiz, J. L.; Reimering, S.; Escobar-Prieto, J. D.; Brancucci, N. M. B.; Echeverry, D. F.; Abdi, A. I.; Marti, M.; Gomez-Diaz, E.; Otto, T. D.
10.1101/2021.07.30.454413 — bioinformatics — Posted on 2023-02-07
3044 Colour patterns are less variable in highly unpalatable nudibranchs
van den Berg, C.; Endler, J. A.; Drummond, L.; Dawson, B. R.; Santiago, C.; Weber, N.; Cheney, K. L.
10.1101/2023.01.30.525844 — animal behavior and cognition — Posted on 2023-02-07
3046 Generate a new crucian carp (Carassius auratus) strain without intermuscular bones by knocking out bmp6
Kuang, Y.; Zheng, X.; Cao, D.; Sun, Z.; Tong, G.; Xu, H.; Yan, T.; Tang, S.; Chen, Z.; Zhang, T.; Zhang, T.; Dong, L.; Yang, X.; Zhou, H.; Guo, W.; Sun, X.
10.1101/2022.11.28.518130 — genetics — Posted on 2023-02-07
3051 SUMOylation of PTEN promotes DNA end resection through directly dephosphorylating 53BP1 in homologous recombination repair
He, J.; Guo, Y.; Deng, R.; Li, L.; Huang, C.; Chen, R.; Wang, Y.; Huang, J.; Cheng, J.; Chen, G.-Q.; Zheng, J.; Zhao, X.; Yu, J.
10.1101/2023.02.06.527258 — cell biology — Posted on 2023-02-07
3052 GLI1 facilitates rheumatoid arthritis by collaborative regulation of DNA methyltransferases
Ge, G.; Guo, Q.; Zhou, Y.; Li, W.; Zhang, W.; Bai, J.; Wang, Q.; Tao, H.; Wang, W.; Wang, Z.; Gan, M.; Xu, Y.; Yang, H.; Li, B.; Geng, D.
10.1101/2023.02.07.527456 — cell biology — Posted on 2023-02-07
3053 Profiling cell envelope-antibiotic interactions reveals vulnerabilities to β-lactams in a multidrug-resistant bacterium
Hogan, A. M.; Natarajan, A.; Maydaniuk, D. T.; Leon, B.; Batun, Z.; Motnenko, A.; Bosch, A.; Cardona, S. T.
10.1101/2022.11.01.510852 — microbiology — Posted on 2023-02-07
3054 Diversity, distribution, and expression of opsin genes in freshwater lakes
He, S.; Linz, A. M.; Stevens, S. L. R.; Tran, P. Q.; Moya-Flores, F.; Oyserman, B. O.; Dwulit-Smith, J. R.; Forest, K. T.; McMahon, K. D.
10.1101/2022.08.01.502354 — microbiology — Posted on 2023-02-07
3055 The Hdc GC box is critical for Hdc gene transcription and histamine-mediated anaphylaxis
Li, Y.; Gao, J.; Zhao, D.; Guan, X.; Morris, S. C.; Finkelman, F. D.; Huang, H.
10.1101/2022.06.13.495950 — immunology — Posted on 2023-02-07
3060 Paclitaxel- and vincristine-induced neurotoxicity and drug transport in sensory neurons
Mortensen, C.; Chua, K. C.; Hammer, H. S.; Nielsen, F.; Poetz, O.; Svenningsen, A. F.; Kroetz, D. L.; Stage, T. B.
10.1101/2023.02.07.527432 — pharmacology and toxicology — Posted on 2023-02-07
3062 GAUT10 is required for Arabidopsis root cell differentiation and elongation
Dash, L.; Swaminathan, S.; Simura, J.; Montes, C.; Solanki, N.; Mejia, L.; Ljung, K.; Zabotina, O.; Kelley, D. R.
10.1101/2023.02.07.527497 — plant biology — Posted on 2023-02-07
3068 A genetic and linguistic analysis of the admixture histories of the islands of Cabo Verde
Laurent, R.; Szpiech, Z. A.; da Costa, S. S.; Thouzeau, V.; Fortes-Lima, C. A.; Dessarps-Freichey, F.; Lemee, L.; Utge, J.; Rosenberg, N. A.; Baptista, M.; Verdu, P.
10.1101/2022.04.11.487833 — genetics — Posted on 2023-02-07
3069 Emergent lag phase in flux-regulation models of diauxie
Bate, F.; Amekan, Y.; Pushkin, M.; Chong, J. P. J.; Bees, M.
10.1101/2023.02.07.527446 — microbiology — Posted on 2023-02-07
3071 Elevated binding and functional antibody responses to SARS-CoV-2 in infants versus mothers
Stoddard, C. I.; Sung, K.; Yaffe, Z. A.; Weight, H.; Beaudoin-Bussieres, G.; Galloway, J. G.; Gantt, S.; Adhiambo, J.; Begnel, E. R.; Ojee, E.; Slyker, J.; Wamalwa, D.; Kinuthia, J.; Finzi, A.; Matsen, F. A.; Lehman, D. A.; Overbaugh, J.
10.1101/2023.02.06.527330 — immunology — Posted on 2023-02-07
3072 A SARS-CoV-2 vaccine designed for manufacturability results in unexpected potency and non-waning humoral response
Campbell, E.; Dobkin, J.; Osorio, L.; Ramasamy, S.; Kumar, R.; SantAngelo, D. B.; Subbian, S.; Denzin, L. K.; Anderson, S.
10.1101/2023.02.06.527376 — immunology — Posted on 2023-02-07
3076 Nucleotide excision repair deficiency is a targetable therapeutic vulnerability in clear cell renal cell carcinoma.
Prosz, A.; Duan, H.; Tisza, V.; Sahgal, P.; Topka, S.; T.Klus, G.; Borscok, J.; Sztupinszki, Z.; Hanlon, T.; Diossy, M.; Vizkeleti, L.; Stormoen, D. R.; Csabai, I.; Pappot, H.; Vijai, J.; Offit, K.; Ried, T.; Sethi, N.; W. Mouw, K.; Spisak, S.; Pathania, S.; Szallasi, Z.
10.1101/2023.02.07.527498 — cancer biology — Posted on 2023-02-07
3077 GSK-3 inhibitor elraglusib enhances tumor-infiltrating immune cell activation in tumor biopsies and synergizes with anti-PD-L1 in a murine model of colorectal cancer
Huntington, K. E.; Louie, A. D.; Srinivasan, P.; Schorl, C.; Lu, S.; Silverberg, D.; Newhouse, D.; Wu, Z.; Zhou, L.; Borden, B.; Giles, F. J.; Dooner, M.; Carneiro, B. A.; El-Deiry, W. S.
10.1101/2023.02.07.527499 — cancer biology — Posted on 2023-02-07
3078 HiExM: high-throughput expansion microscopy enables scalable super-resolution imaging
Boyer, L. A.; Day, J. H.; Maretich, P.; Della Santina, C. M.; Auld, A. L.; Shin, T.; Boyden, E. S.
10.1101/2023.02.07.527509 — bioengineering — Posted on 2023-02-07
3079 A very-low carbohydrate content in a high-fat diet modifies the plasma metabolome and alleviates experimental atherosclerosis
Castro, R.; Kalecky, K.; Huang, N. K.; Peterson, K.; Singh, V.; ROSS, A. C.; Neuberger, T.; Bottiglieri, T.
10.1101/2023.02.07.527515 — biochemistry — Posted on 2023-02-07
3086 Human Cytomegalovirus UL138 Interaction with USP1 Activates STAT1 in infection
Zarrella, K.; Longmire, P.; Zeltzer, S.; Collins-McMillen, D.; Hancock, M.; Buehler, J.; Reitsma, J. M.; Terhune, S. S.; Nelson, J. A.; Goodrum, F.
10.1101/2023.02.07.527452 — microbiology — Posted on 2023-02-07
3087 Transient EZH2 suppression by Tazemetostat during in vitro expansion maintains T cell stemness and improves adoptive T cell therapy
Hou, Y.; Zak, J.; Shi, Y.; Pratumchai, I.; Dinner, B.; Wang, W.; Qin, K.; Weber, E. W.; Teijaro, J.; Wu, P.
10.1101/2023.02.07.527459 — immunology — Posted on 2023-02-07
3088 A cingulate-hippocampal circuit mediates early depressive symptoms in Alzheimer's disease
Chen, Y.; Peng, H.; Zhuang, K.; Xie, W.; Li, C.; Xue, J.; Chen, M.; Huang, X.; Zou, T.; Wang, Y.; Can, D.; Li, H.; Yuan, T.-F.; Zhang, J.
10.1101/2023.02.07.527491 — neuroscience — Posted on 2023-02-07
3090 Coupling Flux Balance Analysis with Reactive Transport Modeling through Machine Learning for Rapid and Stable Simulation of Microbial Metabolic Switching
Song, H.-S.; Ahamed, F.; Lee, J.-Y.; Henry, C. C.; Edirisinghe, J. N.; Nelson, W. C.; Chen, X.; Moulton, J. D.; Scheibe, T. D.
10.1101/2023.02.06.527371 — systems biology — Posted on 2023-02-07
3094 ADP-ribose-acceptor hydrolase 2 (Arh2) deficiency results in cardiac dysfunction, tumorigenesis, inflammation, and decreased survival
Kato, J.; Yamashita, S.; Ishiwata-Endo, H.; Oka, S.; Yu, Z.-X.; Liu, C.; Springer, D.; Noguchi, A.; Peiravi, M.; Hoffmann, V.; Lizak, M. J.; Medearis, M.; Kim, I.-K.; Moss, J.
10.1101/2023.02.07.527494 — cancer biology — Posted on 2023-02-07
3095 A Cas9-fusion proximity-based approach generates an Irak1-Mecp2 tandem duplication mouse model for the study of MeCP2 duplication syndrome.
Maino, E.; Scott, O.; Rizvi, S. Z.; Visuvanathan, S.; Ben Zablah, Y.; Li, H.; Sengar, A. S.; Salter, M. W.; Jia, Z.; Rossant, J.; Cohn, R. D.; Gu, B.; Ivakine, E. A.
10.1101/2023.02.07.527511 — genetics — Posted on 2023-02-07
3096 Identification of site-specific evolutionary trajectories shared across human betacoronaviruses
Escalera-Zamudio, M.; Kosakovsky Pond, S. L.; Martinez de la Vina, N.; Gutierrez, B.; Inward, R. P. D.; Theze, J.; van Dorp, L.; Castelan, H. G.; Bowden, T. A.; Pybus, O. G.; Hulswit, R. J. G.
10.1101/2021.05.24.445313 — evolutionary biology — Posted on 2023-02-07
3097 callsync: an R package for alignment and analysis of multi-microphone animal recordings
Smeele, S. Q.; Tyndel, S. A.; Klump, B. C.; Alarcon-Nieto, G.; Aplin, L. M.
10.1101/2023.02.07.527470 — ecology — Posted on 2023-02-07
3099 Assessing vector competence of mosquitoes from northeastern France to West Nile virus and Usutu virus
Martinet, J.-P.; Bohers, C.; Vazeille, M.; Ferte, H.; Mousson, L.; Mathieu, B.; Depaquit, J.; Failloux, A.-B.
10.1101/2023.02.07.527438 — microbiology — Posted on 2023-02-07
3103 Restricting dietary protein or dietary isoleucine improves metabolic health in aged mice
Yeh, C.-Y.; Chini, L. C. S.; Gallagher, M. S.; Davidson, J. W.; Freichels, I. T.; Calubag, M. F.; Rodgers, A. C.; Green, C. L.; Babygirija, R.; Sonsalla, M. M.; Pak, H. H.; Trautman, M.; Hacker, T. A.; Simcox, J.; Lamming, D.
10.1101/2023.02.06.527311 — physiology — Posted on 2023-02-07
3105 Prioritizing transcription factor perturbations from single-cell transcriptomics
Singh, R.; Li, J. S. S.; Tattikota, S. G.; Liu, Y.; Xu, J.; Hu, Y.; Perrimon, N.; Berger, B.
10.1101/2022.06.27.497786 — bioinformatics — Posted on 2023-02-07
3109 H3K27me3 dictates atypical genome-nuclear lamina interactions and allelic asymmetry during early embryogenesis
Guerreiro, I.; Rang, F. J.; Kawamura, Y. K.; Groenveld, F. C.; van Beek, R. E.; Lochs, S. J. A.; Boele, E.; Peters, A.; Kind, J.
10.1101/2023.02.06.527307 — genomics — Posted on 2023-02-07
3110 T-toxin virulence genes: unconnected dots in a sea of repeats
Haridas, S.; Gonzalez, J. B.; Riley, R.; Koriabine, M.; Yan, M.; Ng, V.; Rightmyer, A.; Grigoriev, I.; Baker, S. E.; Turgeon, B. G.
10.1101/2023.02.06.527415 — genomics — Posted on 2023-02-07
3113 Widespread natural selection on metabolite levels in humans
Timasheva, Y.; Lepik, K.; Liska, O.; Papp, B.; Kutalik, Z.
10.1101/2023.02.07.527420 — genetics — Posted on 2023-02-07
3114 Selecting Covariates for Genome-Wide Association Studies
Dor, E.; Margaliot, I.; Brandes, N.; Zuk, O.; Linial, M.; Rappoport, N.
10.1101/2023.02.07.527425 — genetics — Posted on 2023-02-07
3118 Widespread mermithid nematode parasitism of Cretaceous insects
Luo, C.; Poinar, G. O.; Xu, C.; Zhuo, D.; Jarzembowski, E. A.; Wang, B.
10.1101/2023.02.07.527443 — evolutionary biology — Posted on 2023-02-07
3119 Pollen-feeding delays reproductive senescence and maintains toxicity of Heliconius butterflies
Pinheiro de Castro, E. C.; McPherson, J.; Julian, G.; Mattila, A.; Bak, S.; Montgomery, S.; Jiggins, C.
10.1101/2023.01.13.523799 — evolutionary biology — Posted on 2023-02-07
3120 Single-cell transcriptomic analyses reveal the cellular and genetic basis of aquatic locomotion in scyphozoan jellyfish
Li, Y.; Peng, S.; Liu, Y.; He, K.; Sun, K.; Yu, Z.; Ma, Y.; Wang, F.; Xu, P.; Sun, T.; Zheng, H.; Ye, L.; Wang, L.; Hao, W.; Zhao, J.; Lin, Q.; Chen, K.; Dong, Z.
10.1101/2023.02.06.527379 — ecology — Posted on 2023-02-07
3125 Calcium transients trigger switch-like discharge of prostaglandin E2 (PGE2) in an ERK-dependent manner
Watabe, T.; Yamahira, S.; Takakura, K.; Thumkeo, D.; Narumiya, S.; Matsuda, M.; Terai, K.
10.1101/2023.02.01.526734 — cell biology — Posted on 2023-02-07
3127 Non-destructive DNA metabarcoding of arthropods using collection medium from passive traps
Sire, L.; Schmidt Yanez, P.; Bezier, A.; Courtial, B.; Mbedi, S.; Sparmann, S.; Larrieu, L.; Rougerie, R.; Bouget, C.; Monaghan, M. T.; Herniou, E. A.; Lopez-Vaamonde, C.
10.1101/2023.02.07.527242 — molecular biology — Posted on 2023-02-07
3128 Changes in physicochemical properties and microbial community succession during leaf stacking fermentation
Zhang, G.; Zhao, L.; Li, W.; Yao, H.; Lu, C.; Zhao, G.; Liu, Z.; Wu, Y.; Yang, W.; Li, Y.; Kong, G.
10.1101/2023.02.06.527411 — microbiology — Posted on 2023-02-07
3131 Clade 2.3.4.4b H5N1 high pathogenicity avian influenza virus (HPAIV) from the 2021/22 epizootic is highly duck adapted and poorly adapted to chickens
James, J.; Billington, E.; Warren, C. J.; De Sliva, D.; Di Genova, C.; Airey, M.; Meyer, S. M.; Lewis, T.; Peers-Dent, J.; Thomas, S. S.; Lofts, A.; Furman, N.; Slomka, M. J.; Brown, I. H.; Banyard, A. C.
10.1101/2023.02.07.527270 — microbiology — Posted on 2023-02-07
3132 Aminobisphosphonates reactivate the latent reservoir in people living with HIV-1
Sanz, M.; Weideman, A. M. K.; Ward, A. R.; Clohosey, M. L.; Garcia-Recio, S.; Selitsky, S. R.; Mann, B. T.; Iannone, M. A.; Whitworth, C. P.; Chitrakar, A.; Garrido, C.; Kirchherr, J.; Coffey, A. R.; Tsai, Y.- H.; Samir, S.; Xu, Y.; Copertino, D.; Bosque, A.; Jones, B. R.; Parker, J. S.; Hudgens, M. G.; Goonetilleke, N.; Soriano-Sarabia, N.
10.1101/2023.02.07.527421 — microbiology — Posted on 2023-02-07
3135 The Dual Action of Human Antibodies Specific to Plasmodium falciparum PfRH5 and PfCyRPA: Blocking Invasion and Inactivating Extracellular Merozoites
Weiss, G. E.; Ragotte, R. J.; Quinkert, D.; Lias, A. M.; Dans, M. G.; Boulet, C.; Williams, B. G.; Crabb, B. S.; Draper, S. J.; Gilson, P. R.
10.1101/2023.02.07.527440 — microbiology — Posted on 2023-02-07
3136 A novel cryopreservation and biobanking strategy to study lymphoid tissue stromal cells in human disease
Brandstadter, J. D.; De Martin, A.; Lutge, M.; Ferreira, A.; Gaudette, B. T.; Stanossek, Y.; Wang, S.; Gonzalez, M. V.; Camiolo, E.; Wertheim, G.; Austin, B.; Allman, D.; Lim, M. S.; Fajgenbaum, D. C.; Aster, J. C.; Ludewig, B.; Maillard, I.
10.1101/2023.02.06.525604 — immunology — Posted on 2023-02-07
3140 Evidence for a sensorimotor prediction process in action observation
Hilt, P. M.; Gueugneau, N.; Fadiga, L.; Pozzo, T.; Papaxanthis, C.
10.1101/2023.02.04.527111 — neuroscience — Posted on 2023-02-07
3141 The multidimensional neurocognitive geometry in Alzheimer's disease and posterior cortical atrophy
Ingram, R. U.; Ocal, D.; Halai, A. D.; Pobric, G.; Cash, D.; Crutch, S. J.; Yong, K. X. X.; Lambon Ralph, M. A.
10.1101/2023.02.07.527424 — neuroscience — Posted on 2023-02-07
3144 Liver-specific LXR inhibition represses reverse cholesterol transport in cholesterol-fed mice
Nishida, T.; Ayaori, M.; Arakawa, J.; Suenaga, Y.; Shiotani, K.; Uto-Kondo, H.; Komatsu, T.; Nakaya, K.; Endo, Y.; Sasaki, M.; Ikewaki, K.
10.1101/2023.02.06.527401 — physiology — Posted on 2023-02-07
3146 Accelerated nanopore basecalling with SLOW5 data format
Samarakoon, H.; Ferguson, J. M.; Gamaarachchi, H.; Deveson, I. W.
10.1101/2023.02.06.527365 — bioinformatics — Posted on 2023-02-07
3148 Gaussian Mixture Modeling Extensions for Improved False Discovery Rate Estimation in GC-MS Metabolomics
Flores, J. E.; Bramer, L. M.; Degnan, D. J.; Paurus, V. L.; Corilo, Y. E.; Clendinen, C. S.
10.1101/2023.02.06.527348 — bioinformatics — Posted on 2023-02-07
3150 Radioprotective drug screening in a salivary gland tissue chip.
Piraino, L.; Chen, C.; Mereness, J.; Dunman, P.; Ovitt, C.; Benoit, D.; DeLouise, L.
10.1101/2023.02.06.527345 — bioengineering — Posted on 2023-02-07
3152 Automatic Whole Body FDG PET/CT Lesion Segmentation using Residual UNet and Adaptive Ensemble
Murugesan, G. K.; Mccrumb, D.; Brunner, E.; Kumar, J.; Soni, R.; Grigorash, V.; Chang, A.; VanOss, J.; Moore, S.
10.1101/2023.02.06.525233 — bioengineering — Posted on 2023-02-07
3154 TLR7 activation at epithelial barriers promotes emergency myelopoiesis and lung anti-viral immunity
Jackson, W. D.; Giacomassi, C.; Ward, S.; Owen, A.; Luis, T.; Spear, S.; Woollard, K. J.; Johansson, C.; Strid, J.; Botto, M.
10.1101/2023.02.06.527328 — immunology — Posted on 2023-02-07
3155 Nucleus Accumbens Local Circuit for Cue-Dependent Aversive Learning
Belilos, A.; Gray, C.; Sanders, C.; Richie, C. T.; Sengupta, A.; Hake, H. S.; Francis, T. C.
10.1101/2023.02.06.527338 — neuroscience — Posted on 2023-02-07
3156 ABI5-FLZ13 Module Transcriptionally Represses Growth-related Genes to Delay Seed Germination in Response to ABA
Yang, C.; Li, X.; Chen, S.; Liu, C.; Yang, L.; Li, K.; Liao, J.; Zheng, X.; Li, H.; Li, Y.; Zeng, S.; Zhuang, X.; Rodriguez, P. L.; Luo, M.; Wang, Y.; Gao, C.
10.1101/2023.02.06.527385 — plant biology — Posted on 2023-02-07
3163 The seminal odorant binding protein Obp56g is required for mating plug formation and male fertility in Drosophila melanogaster
Brown, N.; Gordon, B.; McDonough-Goldstein, C. E.; Misra, S.; Findlay, G. D.; Clark, A. G.; Wolfner, M. F.
10.1101/2023.02.03.526941 — genetics — Posted on 2023-02-07
3164 Yeast Farnesyltransferase has broad reactivity with CXXX sequences
Kim, J. H.; Hildebrandt, E. R.; Sarkar, A.; Yeung, W.; Waldon, L. R. A.; Kannan, N.; Schmidt, W. K.
10.1101/2023.02.06.527295 — genetics — Posted on 2023-02-07
3166 SUMOylation of PTEN promotes DNA end resection through directly dephosphorylating 53BP1 in homologous recombination repair
He, J.; Guo, Y.; Deng, R.; Li, L.; Huang, C.; Chen, R.; Wang, Y.; Huang, J.; Cheng, J.; Chen, G.-Q.; Zheng, J.; Zhao, X.; Yu, J.
10.1101/2023.02.06.527258 — cell biology — Posted on 2023-02-07
3167 Syntaxin of plants 32 regulates pollen wall development and pollen tube cell wall integrity via controlling secretory pathway
Liu, Y.; Zhao, X.; Qian, G.; Ma, X.; Song, M.; Qin, G.; Sun, S.; Wang, M.; Gu, K.; Sun, W.; Zhu, J.-K.; Jiang, L.; Li, L.
10.1101/2023.02.03.527076 — molecular biology — Posted on 2023-02-07
3168 Escherichia coli isolated from commercial layer hens in Australia remain susceptible to critically important antimicrobials
Abraham, R.; Allison, H. S.; Lee, T.; Pavic, A.; Chia, R.; Hewson, K.; Lee, Z. Z.; Hampson, D.; Jordan, D.; Abraham, S.
10.1101/2023.02.03.526949 — microbiology — Posted on 2023-02-07
3170 Dynamics of the MRSA Population in A Chilean Hospital: A Phylogenomic Analysis (2000-2016)
Martinez, J. R.; Planet, P. J.; Spencer-Sandino, M.; Rivas, L.; Diaz, L.; Quesille-Villalobos, A.; Riquelme-Neira, R.; Alcalde-Rico, M.; Hanson, B.; Carvajal, L. P.; Rincon, S.; Reyes, J.; Lam, M.; Araos, R.; Garcia, P.; Arias, C. A.; Munita, J. M.
10.1101/2023.02.06.526811 — microbiology — Posted on 2023-02-07
3173 Medial prefrontal cortex stimulation abolishes implicit reactions to threats and prevents the return of fear
Manassero, E.; Concina, G.; Caraig, M. C. C.; Sarasso, P.; Salatino, A.; Ricci, R.; Sacchetti, B.
10.1101/2023.02.06.527256 — neuroscience — Posted on 2023-02-07
3174 A maize lipid droplet-associated protein is modulated by a virus to promote viral multiplication and infection
Wang, S.; Li, S.; Wang, X.; Sun, X.; Xue, M.; Di, D.; Zhang, A.; Zhang, Y.; Xia, Y.; Zhou, T.; Fan, Z.
10.1101/2023.02.02.526882 — pathology — Posted on 2023-02-07
3176 A complex three-dimensional microfluidic model that mimics the early stage events in the human atherosclerotic artery
Maringanti, R.; van Dijk, C. G. M.; Meijer, E. M.; Brandt, M. M.; Krebber, M. M.; Chrifi, I.; Duncker, D. J.; Verhaar, M. C.; Cheng, C.
10.1101/2023.02.02.526873 — cell biology — Posted on 2023-02-07
3177 Antitumor activity of intraperitoneal paclitaxel in orthotopic patient-derived xenograft models of mucinous appendiceal adenocarcinoma
Ito, I.; Dickson, P. N.; Yousef, A. M.; Naini, Z. A.; White, M. G.; Fleten, K. G.; Flatmark, K.; Fournier, K. F.; Fowlkes, N. W.; Shen, J. P.
10.1101/2023.02.01.526672 — cancer biology — Posted on 2023-02-07
3178 Paradoxical activation of oncogenic signaling as a cancer treatment strategy
Dias, M. H.; Friskes, A.; Wang, S.; Fernandes Neto, J. M. H.; Gemert, F. v.; Mourragui, S.; Kuiken, H. J.; Mainardi, S.; Alvarez-Villanueva, D.; Lieftink, C.; Morris, B.; Dekker, A.; Dijk, E. v.; Papagianni, C.; da Silva, M. S.; Jansen, R.; Mulero-Sanchez, A.; Malzer, E.; Vidal, A.; Santos, C.; Salazar, R.; Wailemann, R. A. M.; Torres, T. E. P.; De Conti, G.; Raaijmakers, J.; snaebjornsson, P.; Yuan, S.; Qin, W.; Kovach, J. S.; Armelin, H. A.; te Riele, H.; van Oudenaarden, A.; Jin, H.; Beijersbergen, R.; Villanueva, A.; Medema, R. H.; Bernards, R.
10.1101/2023.02.06.527335 — cancer biology — Posted on 2023-02-07
3179 Inhaled CpG increases survival and synergizes with checkpoint inhibition in lymphangioleiomyomatosis
Amosu, M.; McCright, J. C.; Yang, B.; Fernandez, J. G. d. O.; Moore, K.; Gadde, H. S.; Kaluzienski, M.; Maisel, K.
10.1101/2023.02.06.527331 — immunology — Posted on 2023-02-07
3181 Region-specific homeostatic identity of astrocytes is essential for defining their reactive phenotypes following pathological insults
Makarava, N.; Mychko, O.; Molesworth, K.; Chang, J. C.-Y.; Henry, R. J.; Tsymbalyuk, N.; Gerzanich, V.; Simard, J. M.; Loane, D.; Baskakov, I. V.
10.1101/2023.02.01.526708 — neuroscience — Posted on 2023-02-07
3185 HIV-2 Immature Particle Morphology Provides Insights into Gag Lattice Stability and Virus Maturation
Talledge, N.; Yang, H.; Shi, K.; Coray, R.; Yu, G.; Arndt, W. G.; Meng, S.; Mendonca, L.; Castano-Dlez, D.; Aihara, H.; Mansky, L. M.; Zhang, W.
10.1101/2022.02.01.478508 — microbiology — Posted on 2023-02-06
3186 Co-Targeting IL-6 and EGFR signaling for the treatment of schwannomatosis and associated pain
Yin, Z.; Wu, L.; Zhang, Y.; Sun, Y.; Chen, J. W.; Subudhi, S.; Ho, W.; Lee, G. Y.; Wang, A.; Gao, X.; Ren, J.; Zhu, C.; Zhang, N.; Ferraro, G. B.; Muzikansky, A.; Zhang, L.; Stemmer-Rachamimov, A.; Mao, J.; Plotkin, S. R.; Xu, L.
10.1101/2023.02.06.527377 — neuroscience — Posted on 2023-02-06
3187 The Clustered Gamma Protocadherin Pcdhγc4 Isoform Regulates Cortical Interneuron Programmed Cell Death in the Mouse Cortex.
Mancia Leon, W. R.; Steffen, D. M.; Dale-Huang, F.; Rakela, B.; Breevoort, A.; Romero-Rodriguez, R.; Hasenstaub, A. R.; Stryker, M. P.; Weiner, J. A.; Alvarez-Buylla, A.
10.1101/2023.02.03.526887 — neuroscience — Posted on 2023-02-06
3188 Towards prevention of re-entrant arrhythmias: Injectable hydrogel electrodes enable direct capture of previously inaccessible cardiac tissues
Rodriguez-Rivera, G.; Post, A.; John, M.; Buchan, S.; Wancura, M.; Chwatko, M.; Waldron, C.; Nkansah, A.; Bernard, D.; Kalkunte, N.; Zoldan, J.; Arseneault, M.; Razavi, M.; Cosgriff-Hernandez, E.
10.1101/2021.11.03.467102 — bioengineering — Posted on 2023-02-06
3190 ApoE4 drives maladaptive heterogeneity and immunometabolic responses of astrocytes
Lee, S.; Williams, H. C.; Gorman, A. A.; Devanney, N. A.; Harrison, D. A.; Walsh, A. E.; Goulding, D. S.; Tuck, T.; Schwartz, J. L.; Zajac, D. J.; Macauley, S. L.; Estus, S.; TCW, J.; Johnson, L.; Morganti, J.
10.1101/2023.02.06.527204 — neuroscience — Posted on 2023-02-06
3192 Sulcal morphology of posteromedial cortex substantially differs between humans and chimpanzees
Willbrand, E. H.; Maboudian, S. A.; Kelly, J. P.; Parker, B. J.; Foster, B. L.; Weiner, K. S.
10.1101/2023.02.06.527223 — neuroscience — Posted on 2023-02-06
3197 The maize preligule band is subdivided into distinct domains with contrasting cellular properties prior to ligule outgrowth
Neher, W.; Rasmussen, C. G.; Braybrook, S. A.; Lazetic, V.; Stowers, C. E.; Mooney, P. T.; Sylvester, A. W.; Springer, P. S.
10.1101/2023.02.06.527228 — plant biology — Posted on 2023-02-06
3198 RAB7 deficiency impairs pulmonary artery endothelial function and promotes pulmonary hypertension
Piper, B.; Bogamuwa, S.; Hossain, T.; Farkas, D.; Rosas, L.; Green, A.; Newcomb, G.; Sun, N.; Horowitz, J. C.; Bhagwani, A. R.; Yang, H.; Kudryashova, T. V.; Rojas, M.; Mora, A. L.; Yan, P.; Mallampalli, R. K.; Goncharova, E. A.; Eckmann, D. M.; Farkas, L.
10.1101/2023.02.03.526842 — physiology — Posted on 2023-02-06
3199 Reduced motoneuron excitability and common synaptic inputs of the aged human vastus lateralis
Guo, Y.; Jones, E. J.; Skarabot, J.; Inns, T.; Phillips, B. E.; Atherton, P. J.; Piasecki, M.
10.1101/2023.02.03.526933 — physiology — Posted on 2023-02-06
3204 Cryo-electron tomography of C. elegans mitochondria reveals how the ATP synthase dimer interface shapes crista membranes
Buzzard, E.; McLaren, M.; Bragoszewski, P.; Brancaccio, A.; Ford, H.; Daum, B.; Kuwabara, P.; Collinson, I.; Gold, V.
10.1101/2023.02.02.526626 — biochemistry — Posted on 2023-02-06
3206 Clonal cell states link Barrett's esophagus and esophageal adenocarcinoma
Gier, R. A.; Hueros, R. A. R.; Rong, J.; DeMarshall, M.; Karakasheva, T. A.; Muir, A. B.; Falk, G. W.; Zhang, N. R.; Shaffer, S. M.
10.1101/2023.01.26.525564 — genomics — Posted on 2023-02-06
3212 Standing genetic variation and chromosome differences drove rapid ecotype formation in a major malaria vector
Small, S. T.; Costantini, C.; Sagnon, N.; Guelbeogo, M. W.; Emrich, S. J.; Kern, A. D.; Fontaine, M. C.; Besansky, N. J.
10.1101/2022.11.21.517335 — evolutionary biology — Posted on 2023-02-06
3214 Wolbachia genomics reveals a potential for a nutrition-based symbiosis in blood-sucking Triatomine bugs
Filee, J.; Agesilas-Lequeux, K.; Lacquehay, L.; Berenger, J. M.; Dupont, L.; Mendonca, V.; Aristeu da Rosa, J.; Harry, M.
10.1101/2022.09.06.506778 — evolutionary biology — Posted on 2023-02-06
3215 Soil legacies of extreme droughts enhance the performance of invading plants
Thakur, M. P.; Sloot, M. v. d.; Wilschut, R.; Hannula, S. E.; Hooven, F. t.; Geisen, S.; Quist, C.; Steinauer, K.; Putten, W. v. d.
10.1101/2023.01.30.526304 — ecology — Posted on 2023-02-06
3218 Mechanistic Modeling Explains the Production Dynamics of Recombinant Adeno-Associated Virus with the Baculovirus Expression Vector System
Destro, F.; Srinivasan, P.; Kanter, J. M.; Neufeld, C.; Wolfrum, J. M.; Barone, P. W.; Springs, S. L.; Sinskey, A. J.; Cecchini, S.; Kotin, R. M.; Braatz, R. D.
10.1101/2023.02.04.527082 — molecular biology — Posted on 2023-02-06
3219 Linking prokaryotic genome size variation to metabolic potential and environment
Rodriguez-Gijon, A.; Buck, M.; Andersson, A. F.; Izabel-Shen, D.; Nascimento, F. J. A.; Garcia, S. L.
10.1101/2022.10.20.512849 — microbiology — Posted on 2023-02-06
3221 Marine picoplankton metagenomes from eleven vertical profiles obtained by the Malaspina Expedition in the tropical and subtropical oceans
Sanchez, P.; Sebastian, M.; Pernice, M. C.; Rodriguez-Martinez, R.; Pesant, S.; Agusti, S.; Gojobori, T.; Logares, R.; Sala, M. M.; Vaque, D.; Massana, R.; Duarte, C. M.; Acinas, S. G.; Gasol, J. M.
10.1101/2023.02.06.526790 — microbiology — Posted on 2023-02-06
3223 Quantitative analyses of interactions between SpoVG and RNA/DNA
Saylor, T. C.; Savage, C. R.; Krusensjerna, A. C.; Jusufovic, N.; Zueckert, W. R.; Brissette, C. A.; MOTALEB, M. A.; Schlax, P. J.; Stevenson, B.
10.1101/2023.02.06.527361 — microbiology — Posted on 2023-02-06
3227 Effort cost of harvest affects decisions and movement vigor of marmosets during foraging
Hage, P.; Jang, I. K.; Looi, V.; Fakharian, M. A.; Orozco, S. P.; Sedaghat-Nejad, E.; Pi, J.; Shadmehr, R.
10.1101/2023.02.04.527146 — neuroscience — Posted on 2023-02-06
3229 A thin-film optogenetic visual prosthesis
Knudsen, E. B.; Zappitelli, K.; Brown, J.; Reeder, J.; Smith, K. S.; Rostov, M.; Choi, J.; Rochford, A.; Slager, N.; Miura, S. K.; Rodgers, K.; Reed, A.; Lewis Israeli, Y. R.; Shiraga, S.; Seo, K. J.; Wolin, C.; Dawson, P.; Eltaeb, M.; Dasgupta, A.; Rothman, M.; Yoon, E.; Chong, P.; Charles, S.; Stewart, J. M.; Silva, R. A.; Kim, T.; Kong, Y.; Mardinly, A. R.; Hodak, M.
10.1101/2023.01.31.526482 — neuroscience — Posted on 2023-02-06
3231 Functional Connectivity of the Cerebellar Vermis in Bipolar Disorder and Associations with Mood
Saleem, A.; Harmata, G.; Jain, S.; Voss, M. W.; Fiedorowicz, J. G.; Williams, A. J.; Shaffer, J. J.; Richards, J. G.; Barsotti, E. J.; Sathyaputri, L.; Schmitz, S. L.; Christensen, G. E.; Long, J. D.; Xu, J.; Wemmie, J. A.; Magnotta, V.
10.1101/2023.02.02.526878 — neuroscience — Posted on 2023-02-06
3233 A critical analysis of plant science literature reveals ongoing inequities
Marks, R. A.; Amezquita, E. J.; Percival, S.; Rougon-Cardoso, A.; Chibici-Revneanu, C.; Tebele, S. M.; Farrant, J. M.; Chitwood, D. H.; VanBuren, R.
10.1101/2022.10.15.512190 — plant biology — Posted on 2023-02-06
3236 Mono-ADP-ribosyltransferase 1 (Artc1)-deficiency decreases tumorigenesis, increases inflammation, decreases cardiac contractility, and reduces survival
Ishiwata-Endo, H.; Kato, J.; Oda, H.; Sun, J.; Yu, Z.-X.; Liu, C.; Springer, D. A.; Dagur, P. K.; Lizak, M. J.; Murphy, E.; Moss, J.
10.1101/2023.02.06.527366 — cancer biology — Posted on 2023-02-06
3241 Flexible and cost-effective genomic surveillance of P. falciparum malaria with targeted nanopore sequencing
de Cesare, M.; Mwenda, M.; Jeffreys, A. E.; Chirwa, J.; Drakeley, C.; Schneider, K.; Ghinai, I.; Busby, G. B.; Hamainza, B.; Hawela, M.; Bridges, D. J.; Hendry, J. A.
10.1101/2023.02.06.527333 — genomics — Posted on 2023-02-06
3242 Metagenomics of culture isolates and insect tissue illuminate the evolution of Wolbachia, Rickettsia and Bartonella symbionts in Ctenocephalides spp. fleas
Beliavskaia, A.; Tan, K.-K.; Sinha, A.; Husin, N. A.; Lim, F. S.; Loong, S. K.; Bell-Sakyi, L.; Carlow, C. K. S.; Abubakar, S.; Darby, A. C.; Makepeace, B. L.; Khoo, J. J.
10.1101/2023.02.06.527313 — genomics — Posted on 2023-02-06
3244 Systematically testing human HMBS missense variants to reveal mechanism and pathogenic variation
van Loggerenberg, W.; Sowlati-Hashjin, S.; Weile, J.; Hamilton, R.; Chawla, A.; Gebbia, M.; Kishore, N.; Fresard, L.; Mustajoki, S.; Pischik, E.; Di Pierro, E.; Barbaro, M.; Floderus, Y.; Schmitt, C.; Gouya, L.; Colavin, A.; Nussbaum, R.; Friesema, E. C. H.; Kauppinen, R.; To-Figueras, J.; Aarsand, A. K.; Desnick, R. J.; Garton, M.; Roth, F. P.
10.1101/2023.02.06.527353 — molecular biology — Posted on 2023-02-06
3246 An Anaplasma phagocytophilum T4SS effector, AteA, is essential for tick infection
Park, J. M.; Genera, B. M.; Fahy, D.; Swallow, K. T.; Nelson, C. M.; Oliver, J. D.; Shaw, D. K.; Munderloh, U. G.; Brayton, K. A.
10.1101/2023.02.06.527355 — microbiology — Posted on 2023-02-06
3250 Prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection with early activation of memory T cells followed by production of potent neutralizing antibodies
Painter, M. M.; Johnston, T. S.; Lundgreen, K. A.; Santos, J. J. S.; Qin, J. S.; Goel, R. R.; Apostolidis, S. A.; Mathew, D.; Fulmer, B.; Williams, J. C.; McKeague, M. L.; Pattekar, A.; Goode, A.; Nasta, S.; Baxter, A. E.; Giles, J. R.; Skelly, A. N.; Felley, L. E.; McLaughlin, M.; Weaver, J.; Penn Medicine BioBank, ; Kuthuru, O.; Dougherty, J.; Adamski, S.; Long, S.; Kee, M.; Clendenin, C.; da Silva Antunes, R.; Grifoni, A.; Weiskopf, D.; Sette, A.; Huang, A. C.; Rader, D. J.; Hensley, S. E.; Bates, P.; Greenplate, A. R.; Wherry, E. J.
10.1101/2023.02.05.527215 — immunology — Posted on 2023-02-06
3252 Nova proteins direct synaptic integration of somatostatin interneurons through activity-dependent alternative splicing
Ibrahim, L. A.; Wamsley, B.; Alghamdi, N.; Yusuf, N.; Sevier, E.; Hairston, A.; Sherer, M.; Jaglin, X. H.; Xu, Q.; Gao, L.; Khodadadi-Jamayran, A.; Favuzzi, E.; Yuan, Y.; Dimidschstein, J.; Darnell, R.; Fishell, G.
10.1101/845230 — neuroscience — Posted on 2023-02-06
3259 The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ
Li, X.; Hernandez, I.; Haggblad, M.; Lidemalm, L.; Brautigam, L.; Lucas, J. J.; Carreras-Puigvert, J.; Huhn, D.; Fernandez-Capetillo, O.
10.1101/2023.02.06.527298 — neuroscience — Posted on 2023-02-06
3261 Flexible visual learning and memory in nectar foraging hornets
Lacombrade, M.; Bajo, M. D.; Rocher, N.; Navarro, E.; Lubat, C.; Vogelweith, F.; Thiery, D.; Lihoreau, M.
10.1101/2023.02.06.527296 — animal behavior and cognition — Posted on 2023-02-06
3263 Bird wings are shaped by thermoregulatory demand for heat dissipation
Weeks, B. C.; Harvey, C.; Tobias, J. A.; Sheard, C.; Zhou, Z.; Fouhey, D. F.
10.1101/2023.02.06.527306 — ecology — Posted on 2023-02-06
3265 Mechanism of sensor kinase CitA transmembrane signaling
Zhang, X.; Xue, K.; Salvi, M.; Schomburg, B.; Mehrens, J.; Giller, K.; Stopp, M.; Weisenburger, S.; Boening, D.; Sandoghdar, V.; Unden, G.; Becker, S.; Andreas, L. B.; Griesinger, C.
10.1101/2023.02.06.527302 — molecular biology — Posted on 2023-02-06
3269 TFEB-vacuolar ATPase signaling regulates lysosomal function and microglial activation in tauopathy
Wang, B.; Martini-Stoica, H.; Qi, C.; Lu, T.-C.; Wang, S.; Xiong, W.; Qi, Y.; Xu, Y.; Sardiello, M.; Li, H.; Zheng, H.
10.1101/2023.02.06.527293 — neuroscience — Posted on 2023-02-06
3271 p53 and RB Cooperate to Suppress Transposable Elements
Lopez, O. M.; Zhang, M.; Hendrickson, P. G.; Huang, J.; Daniels, A. R.; Blackmer, J.; Luo, L.; Attardi, L. D.; Corcoran, D.; Kirsch, D. G.
10.1101/2023.02.06.527304 — cancer biology — Posted on 2023-02-06
3272 Helixer--de novo Prediction of Primary Eukaryotic Gene Models Combining Deep Learning and a Hidden Markov Model.
Holst, F.; Bolger, A.; Günther, C.; Mass, J.; Kindel, F.; Triesch, S.; Kiel, N.; Saadat, N.; Ebenhöh, O.; Usadel, B.; Schwacke, R.; Bolger, M.; Weber, A. P. M.; Denton, A. K.
10.1101/2023.02.06.527280 — bioinformatics — Posted on 2023-02-06
3273 A Zika virus-responsive sensor-effector system in Aedes aegypti
Basu, S.; Reitmayer, C. M.; Lumley, S.; Atkinson, B.; Schade-Weskott, M. L.; Rooney, S.; Larner, W.; Montiel, E. E.; Gutierrez-Lopez, R.; Levitt, E.; Munyanduki, H. M.; Elrefaey, A. M. E.; Clarke, A. T.; Koit, S.; Zusinaite, E.; Fragkoudis, R.; Merits, A.; Alphey, L.
10.1101/2023.02.06.527261 — bioengineering — Posted on 2023-02-06
3274 Image-guided deployment and monitoring of a novel tungsten nanoparticle-infused radiopaque absorbable inferior vena cava filter in pig
San Valentin, E. M. D.; Damasco, J. A.; Bernardino, M.; Court, K. A.; Godin, B.; Canlas, G. M.; Melancon, A. D.; Chintalapani, G.; Jacobsen, M. C.; Norton, W.; Layman, R. R.; Fowlkes, N.; Chen, S.; Huang, S. Y.; Melancon, M. P.
10.1101/2023.02.06.527049 — bioengineering — Posted on 2023-02-06
3275 Excess PrPC inhibits muscle cell differentiation via miRNA-enhanced liquid-liquid phase separation implicated in myopathy
Tao, J.; Zeng, Y.; Dai, B.; Liu, Y.; Pan, X.; Wang, L.-Q.; Chen, J.; Zhou, Y.; Lu, Z.; Xie, L.; Liang, Y.
10.1101/2023.02.06.527278 — biochemistry — Posted on 2023-02-06
3276 Structural basis for inactivation of PRC2 by G-quadruplex RNA
Song, J.; Gooding, A. R.; Hemphill, W. O.; Kasinath, V.; Cech, T. R.
10.1101/2023.02.06.527314 — biochemistry — Posted on 2023-02-06
3278 Body size-dependent effects on the distribution patterns of phoretic mites of the multi-symbiont Rhynchophorus ferrugineus (Olivier, 1790) host
Matos, I.; Silva, D.; Oliveira, J.; Goncalves, C.; Alves, R.; Pereira, N.; Catarino, F.; Ameixa, O. M. C. C.; Sousa, J. A.; Rangel, L. F.; Santos, M. J.; AYRA-PARDO, C.
10.1101/2023.02.06.527267 — ecology — Posted on 2023-02-06
3279 Hormonal Interventions for optimizing reproductive efficiency in pigs at Farmers field
Kumar, S.; Islam, R.; Banik, S.; Barman, K.; Das, P. J.; Mohan, N.; Kumar, S.; Gupta, V. K.
10.1101/2023.02.06.527245 — physiology — Posted on 2023-02-06
3280 Overcoming clinical resistance to EZH2 inhibition using rational epigenetic combination therapy
Kazansky, Y.; Cameron, D.; Demarest, P.; Zaffaroni, N.; Arrighetti, N.; Zuco, V.; Kuwahara, Y.; Qu, R.; De Stanchina, E.; Dela Cruz, F. S.; Kung, A. L.; Gounder, M.; Kentsis, A.
10.1101/2023.02.06.527192 — cancer biology — Posted on 2023-02-06
3281 xTrimoDock: Rigid Protein Docking via Cross-Modal Representation Learning and Spectral Algorithm
Luo, Y.; Li, S.; Sun, Y.; Wang, R.; Tang, T.; Hongdu, B.; Cheng, X.; Shi, C.; Li, H.; Song, L.
10.1101/2023.02.06.527251 — bioinformatics — Posted on 2023-02-06
3287 Oviposition-related behaviours of Limenitis camilla in a common garden experiment
Marcantonio, M.; Voda, R.; Da Re, D.; Igot, Q.; Dennis, R.; Vielfaure, A.; Vanwambeke, S.; Nieberding, C.
10.1101/2023.02.06.527247 — animal behavior and cognition — Posted on 2023-02-06
3288 NLRP1 inflammasome modulates senescence and senescence-associated secretory phenotype
Muela-Zarzuela, I.; Suarez-Rivero, J. M.; Gallardo-Orihuela, A.; Wang, C.; Izawa, K.; de Gregorio-Procopio, M.; Couillin, I.; Ryffel, B.; Kitaura, J.; Sanz, A.; von Zglinicki, T.; Mbalaviele, G.; Cordero, M. D.
10.1101/2023.02.06.527254 — immunology — Posted on 2023-02-06
3289 Innate receptors with high specificity for HLA class I-peptide complexes
Sim, M. J. W.; Brennan, P.; Wahl, K. L.; Lu, J.; Rajagopalan, S.; Sun, P. D.; Long, E. O.
10.1101/2023.02.06.527249 — immunology — Posted on 2023-02-06
3294 Low Density Lipoprotein Receptor-Related Protein 1 (LRP1) as an auxiliary host factor for RNA viruses including SARS-CoV-2
Devignot, S.; Sha, T. W.; Burkard, T. R.; Schmerer, P.; Hagelkruys, A.; Mirazimi, A.; Elling, U.; Penninger, J. M.; Weber, F.
10.1101/2022.02.17.480904 — microbiology — Posted on 2023-02-06
3295 Quantitative proteomic analysis reveals apoE4-dependent phosphorylation of the actin-regulating protein VASP
Cakir, Z.; Lord, S. J.; Zhou, Y.; Jang, G. M.; Polacco, B. J.; Eckhardt, M.; Jimenez-Morales, D.; Newton, B. W.; Orr, A. L.; Johnson, J. R.; da Cruz, A.; Mullins, D.; Krogan, N. J.; Mahley, R. W.; Swaney, D. L.
10.1101/2022.06.06.495052 — neuroscience — Posted on 2023-02-06
3297 TXNIP in liver sinusoidal endothelial cells ameliorates alcohol-associated liver disease
Jung, E.; Baek, E. B.; Hong, E.-J.; Kang, J. H.; Park, S.; Hong, E.-J.; Cho, Y.-E.; Ko, J.-W.; Won, Y.-S.; Kwon, H.-J.
10.1101/2023.01.30.526192 — pathology — Posted on 2023-02-06
3304 Constitutive protein degradation induces acute cell death via proteolysis products
Chen, S.-H.; Prakash, S.; Helgason, E.; Gilchrist, C. L.; Kenner, L. R.; Srinivasan, R.; Sterne-Weiler, T.; Hafner, M.; Piskol, R.; Dueber, E. C.; Hamidi, H.; Endres, N.; Ye, X.; Fairbrother, W. J.; Wertz, I. E.
10.1101/2023.02.06.527237 — cell biology — Posted on 2023-02-06
3306 Signatures of antibiotic tolerance and persistence in response to divergent stresses
Wang, H.; McElfresh, G.; Wijesuriya, N.; Podgorny, A.; Hecht, A. D.; Ray, C. J.
10.1101/2023.02.05.527212 — microbiology — Posted on 2023-02-06
3308 Genetic timeline of human brain and cognitive traits
Libedinsky, I.; Wei, Y.; de Leeuw, C.; Rilling, J.; Posthuma, D.; van den Heuvel, M.
10.1101/2023.02.05.525539 — genetics — Posted on 2023-02-06
3309 The kinesin Kif21b regulates radial migration of cortical projection neurons through a noncanonical function on actin cytoskeleton.
Rivera Alvarez, J.; Asselin, L.; Tilly, P.; Benoit, R.; Batisse, C.; Richert, L.; Batisse, J.; Morlet, B.; Levet, F.; Schwaller, N.; Mely, Y.; Ruff, M.; Reymann, A.-C.; GODIN, J. D.
10.1101/2023.02.06.526840 — neuroscience — Posted on 2023-02-06
3314 Risk of mitochondrial deletions is affected by the global secondary structure of the human mitochondrial genome
Shamanskiy, V.; Mikhailova, A. A.; Ushakova, K.; Mikhailova, A. G.; Oreshkov, S.; Knorre, D.; Tretiakov, E. O.; Ree, N.; Overdevest, J. B.; Lukowski, S. W.; Gostimskaya, I.; Yurov, V.; Liou, C.-W.; Lin, T.-K.; Kunz, W. S.; Reymond, A.; Mazunin, I.; Bazykin, G. A.; Gunbin, K.; Fellay, J.; Tanaka, M.; Khrapko, K.; Popadin, K.
10.1101/603282 — genetics — Posted on 2023-02-06
3316 Microplastics are present in women's and cows' follicular fluid and polystyrene microplastics compromise bovine oocyte function in vitro
Grechi, N.; Franko, R.; Rajaraman, R.; Stoeckl, J. B.; Trapphoff, T.; Dieterle, S.; Frohlich, T.; Noonan, M.; de Almeida Monteiro Melo Ferraz, M.
10.1101/2022.11.04.514813 — developmental biology — Posted on 2023-02-06
3320 A Prefrontal Neural Circuit for Maternal Behavioural Learning in Mice
Tasaka, G.-i.; Hagihara, M.; Irie, S.; Kobayashi, H.; Inada, K.; Kihara, M.; Abe, T.; Miyamichi, K.
10.1101/2023.02.03.527077 — neuroscience — Posted on 2023-02-05
3322 SoyOmics: A deeply integrated database on soybean multi omics
Liu, Y.; Zhang, Y.; Liu, X.; Shen, Y.; Tian, D.; Yang, X.; Liu, S.; Ni, L.; Zhang, Z.; Song, S.; Tian, Z.
10.1101/2023.02.05.527102 — bioinformatics — Posted on 2023-02-05
3323 High-resolution lac insect genome assembly provides genetic insights into lac synthesis and evolution of scale insects
Wang, W. w.; Chen, X. m.; Bashir, N. H.; Lu, Q.; Zhang, J. w.; Ling, X. f.; Ding, W. f.; Chen, H.
10.1101/2023.02.05.526168 — genomics — Posted on 2023-02-05
3324 Genomic signatures of bottleneck and founder effects in dingoes
Kumar, M.; Conroy, G.; Ogbourne, S.; Cairns, K.; Borburgh, L.; Subramanian, S.
10.1101/2023.02.05.527211 — evolutionary biology — Posted on 2023-02-05
3327 Loss of EED in the oocyte causes initial fetal growth restriction followed by placental hyperplasia and offspring overgrowth
Oberin, R.; Petautschnig, S.; Tsai, T.; Jarred, E. G.; Qu, Z.; Youngson, N. A.; Bildsoe, H.; Truong, T. T.; Fernando, D.; van den Buuse, M.; Gardner, D. K.; Sims, N. A.; Adelson, D. L.; Western, P. S.
10.1101/2022.08.08.503175 — developmental biology — Posted on 2023-02-05
3329 Targeted cancer therapy induces APOBEC fuelling the evolution of drug resistance
Caswell, D. R.; Mayekar, M. K.; Gui, P.; Law, E. K.; Vokes, N. I.; Ruiz, C. M.; Dietzen, M.; Angelova, M.; Bailey, C.; Pich, O.; Bakker, B.; Wu, W.; Humpton, T. J.; Kerr, D. L.; Hill, W.; Lu, W.-T.; Haderk, F.; Blakely, C. M.; Bakir, M. A.; Nagano, A.; Gimeno-Valiente, F.; Weeden, C.; Rowan, A.; McCoach, C. E.; Almeida, B.; Green, M.; Gomez, C.; Gini, B.; Nanjo, S.; Barbosa, D.; Moore, C.; Przewrocka, J.; Gronroos, E.; Priestnall, S.; Suarez-Bonnet, A.; Zverev, C.; Lighterness, S.; Cormack, J.; Olivas, V.; Cech, L.; Rule, B.; Ashford, P.; Durfee, C.; Temiz, N. A.; Tan, L.; Larson, L. K.; Argyr
10.1101/2020.12.18.423280 — cancer biology — Posted on 2023-02-05
3333 Cultivation of the polyextremophile Cyanidioschyzon merolae 10D during summer conditions on the coast of the Red Sea and its adaptation to hypersaline sea water
Villegas, M. V.; Gonzalez-Portela, R. E.; Bastos de Freitas, B.; AlJahdali, A.; Romero-Villegas, G. I.; Abdulsalam, R.; Kapoore, R. V.; Fuentes-Grunewald, C.; Lauersen, K. J.
10.1101/2023.02.02.526792 — bioengineering — Posted on 2023-02-05
3334 Genomic Changes During the Evolution of the Coxiella Genus Along the Parasitism-Mutualism Continuum.
Santos-Garcia, D.; Morel, O.; Henri, H.; El Filali, A.; Buysse, M.; Noël, V.; McCoy, K. D.; Gottlieb, Y.; Klasson, L.; Zenner, L.; Duron, O.; Vavre, F.
10.1101/2022.10.26.513839 — microbiology — Posted on 2023-02-05
3336 Screening autism-associated environmental factors in differentiating human neural progenitors with fractional factorial design-based transcriptomics
Arora, A.; Becker, M.; Marques, C.; Oksanen, M.; Li, D.; Mastropasqua, F.; Watts, M. E.; Arora, M.; Falk, A.; Daub, C. O.; Lanekoff, I.; Tammimies, K.
10.1101/2022.06.27.497311 — neuroscience — Posted on 2023-02-05
3337 Heat-induced seizures, premature mortality, and hyperactivity in a novel Scn1a nonsense model for Dravet syndrome
Mavashov, A.; Brusel, M.; Liu, J.; Woytowicz, V.; Bae, H.; Chen, Y.-H.; Dani, V. S.; Cardenal, E.; Spinosa, V.; Aibar, J. A.; Rubinstein, M.
10.1101/2023.02.01.526678 — neuroscience — Posted on 2023-02-05
3338 Engineering of NEMO as calcium indicators with large dynamics and high sensitivity
Li, J.; Shang, Z.; Chen, J.-H.; Gu, W.; Yao, L.; Yang, X.; Sun, X.; Wang, L.; Wang, T.; Liu, S.; Li, J.; Hou, T.; Xing, D.; Gill, D. L.; Li, J.; Wang, S.-Q.; Hou, L.; Zhou, Y.; Tang, A.-H.; Zhang, X.; Wang, Y.
10.1101/2022.08.23.504677 — synthetic biology — Posted on 2023-02-05
3339 Antidiabetic and in silico molecular docking of Xeroderris stuhlmannii (Taub.) Mendonca & E.P. Sousa phytochemical compounds on human α-glucosidases
Nyathi, B.; Bvunzawabaya, J. T.; Mudawarima, C. V. P.; Manzombe, E.; Selemani, M. A.; Tsotsoro, K.; Munyuki, G.; Rwere, F.
10.1101/2022.09.16.508336 — plant biology — Posted on 2023-02-05
3341 Nitrogenase resurrection and the evolution of a singular enzymatic mechanism
Garcia, A. K.; Harris, D.; Rivier, A.; Carruthers, B.; Barros, A. P.; Seefeldt, L.; Kacar, B.
10.1101/2022.05.17.492308 — evolutionary biology — Posted on 2023-02-05
3342 Cancer relevance of circulating antibodies against LINE-1 antigens in humans
Vylegzhanina, A.; Bespalov, I.; Novototskaya-Vlasova, K.; Hall, B.; Gleiberman, A.; Yu, H.; Leontieva, O.; Leonova, K.; Kurnasov, O.; Osterman, A.; Dy, G.; Komissarov, A.; Vasilieva, E.; Gehlhausen, J.; Iwasaki, A.; Ambrosone, C.; Tsuji, T.; Matsuzaki, J.; Odunsi, K.; Andrianova, E.; Gudkov, A. V.
10.1101/2023.02.03.526997 — cancer biology — Posted on 2023-02-05
3344 Mob4 is essential for spermatogenesis in Drosophila melanogaster
Santos, I. B.; Wainman, A.; Maraver, J. G.; Pires, V.; Kovacs, L.; Riparbelli, M. G.; Callaini, G.; Glover, D. M.; Tavares, A. A.
10.1101/2023.02.05.527206 — developmental biology — Posted on 2023-02-05
3346 Human FAM111A inhibits vaccinia virus replication by degrading viral uncoating factor I3 and is antagonized by poxvirus host range factor SPI-1
Zhu, J.; Gao, X.; Zhang, Z.; Deng, Y.; Xie, S.; Ren, S.; Li, Y.; Li, H.; Niu, K.; Fu, S.; Li, Y.; Moss, B.; Wu, W.; Peng, C.
10.1101/2023.02.04.527148 — microbiology — Posted on 2023-02-05
3347 Cellular iron governs the host response to malaria
Wideman, S. K.; Frost, J. N.; Richter, F. C.; Naylor, C.; Lopes, J. M.; Viveiros, N.; Teh, M. R.; Preston, A. E.; White, N.; Yusuf, S.; Draper, S.; Armitage, A. E.; Duarte, T. L.; Drakesmith, H.
10.1101/2023.02.05.527208 — immunology — Posted on 2023-02-05
3348 Pramipexole restores behavioral inhibition in highly impulsive rats through a paradoxical modulation of frontostriatal networks
Magnard, R.; Fouyssac, M.; Vachez, Y. M.; Cheng, Y.; Dufourd, T.; Carcenac, C.; Boulet, s.; Janak, P. H.; Savasta, M.; Belin, D.; Carnicella, S.
10.1101/2023.02.05.527198 — neuroscience — Posted on 2023-02-05
3349 C-terminus induced asymmetry within a Rad52 homodecamer dictates single-position Rad51 nucleation in homologous recombination
Deveryshetty, J.; Chadda, R.; Mattice, J.; Karunakaran, S.; Rau, M.; Basore, K.; Pokhrel, N.; Englander, N.; Fitzpatrick, J.; Bothner, B.; Antony, E.
10.1101/2023.02.05.527205 — biochemistry — Posted on 2023-02-05
3355 Brainstem Dbh+ Neurons Control Chronic Allergen-Induced Airway Hyperreactivity
Su, Y.; Xu, J.; Zhu, Z.; Yu, H.; Nudell, V. S.; Dash, B.; Moya, E.; Ye, L.; Nimmerjahn, A.; Sun, X.
10.1101/2023.02.04.527145 — cell biology — Posted on 2023-02-05
3356 Cochlear dysfunction as an early biomarker for cognitive decline in normal hearing and mild hearing loss
Medel, V.; Delano, P. H.; Belkhiria, C.; Leiva, A.; De Gatica, C.; Vidal, V.; Navarro, C. F.; San Martin, S.; Martinez, M.; Gierke, C.; Garcia, X.; Cerda, M.; Vergara, R.; Delgado, C.; Farias, G.
10.1101/2023.02.03.527051 — neuroscience — Posted on 2023-02-05
3359 Network-based molecular subtyping of acral melanoma
Yin, M.; Zhang, Y.; Wang, W.; Zhao, S.; Su, J.; Li, S.; Chen, X.
10.1101/2023.02.04.527155 — bioinformatics — Posted on 2023-02-05
3362 High-Quality Nuclei Isolation from Postmortem Human Heart Muscle Tissues for Single-Cell Studies
Araten, S.; Mathieu, R.; Jetly, A.; Shin, H.; Hilal, N.; Zhang, B.; Morillo, K.; Nandan, D.; Sivankutty, I.; Chen, M. H.; Choudhury, S.
10.1101/2023.02.05.526322 — genetics — Posted on 2023-02-05
3363 Leveraging type 1 diabetes human genetic and genomic data in the T1D Knowledge Portal
Kudtarkar, P.; Costanzo, M.; Sun, Y.; Jang, D.; Koesterer, R.; Mychaleckyj, J. C.; Nayak, U.; Onengut-Gumuscu, S.; Rich, S. S.; Flannick, J. A.; Gaulton, K. J.; Burtt, N. P.
10.1101/2023.02.03.526066 — genetics — Posted on 2023-02-05
3367 Nomadic ungulate movements under threat: Declining mobility of Mongolian gazelles in the Eastern Steppe.
Mendgen, P.; Dejid, N.; Olson, K.; Buuveibaatar, B.; Calabrese, J. M.; Chimeddorj, B.; Dalannast, M.; Fagan, W. F.; Leimgruber, P.; Mueller, T.
10.1101/2023.02.05.526430 — ecology — Posted on 2023-02-05
3369 Vaccinia virus induces EMT-like transformation and RhoA-mediated mesenchymal migration
Liu, W.; Lu, J.-Y.; Wang, Y.-J.; Xu, X.-x.; Chen, Y.-C.; Yu, S.-X.; Xiang, X.-W.; Chen, X.-Z.; Jiu, Y.; Gao, H.; Sheng, M.; Chen, Z.-J.; Hu, X.; Li, D.; Maiuri, P.; Huang, X.; Ying, T.; Xu, G.-L.; Pang, D.-W.; Zhang, Z.-L.; Liu, B.; Liu, Y.-J.
10.1101/2023.02.04.527154 — cell biology — Posted on 2023-02-05
3370 Lost in HELLS: disentangling the mystery of SALNR existence in senescence cellular models
Battaglia, C.; Consiglio, A.; Venturin, M.; Briguglio, S.; Rossi, C.; Grillo, G.; Bellosta, S.; Cattaneo, M. G.; Licciulli, F.
10.1101/2023.02.03.526712 — molecular biology — Posted on 2023-02-05
3372 Mechanistic Modeling Explains the Production Dynamics of Recombinant Adeno-Associated Virus with the Baculovirus Expression Vector System
Destro, F.; Srinivasan, P.; Kanter, J. M.; Neufeld, C.; Wolfrum, J. M.; Barone, P. W.; Springs, S. L.; Sinskey, A. J.; Cecchini, S.; Kotin, R. M.; Braatz, R. D.
10.1101/2023.02.04.527082 — molecular biology — Posted on 2023-02-05
3375 NaV1.7 mRNA and protein expression in putative projection neurons of the human spinal dorsal horn
Shiers, S.; Funk, G.; Cervantes, A.; Horton, P.; Dussor, G.; Hennen, S.; Price, T. J.
10.1101/2023.02.04.527110 — neuroscience — Posted on 2023-02-05
3377 Transcriptional networks predating cognition-associated pyramidal lineages are restructured by erythropoietin
Singh, M.; Zhao, Y.; Daguano Gastaldi, V.; Wojcik, S. M.; Curto, Y.; Kawaguchi, R.; Merino, R. M.; Fernandez Garcia-Agudo, L.; Taschenberger, H.; Brose, N.; Geschwind, D.; Nave, K.-A.; Ehrenreich, H.
10.1101/2023.02.04.527116 — neuroscience — Posted on 2023-02-05
3380 MpoxRadar: a worldwide Mpox genomic surveillance dashboard
Nasri, F.; Wittig, A.; Kongkitimanon, K.; Sanchez Cortes, J.; Brinkmann, A.; Nitsche, A.; Schmachtenberg, A.-J.; Renard, B. Y.; Fuchs, S.
10.1101/2023.02.03.526935 — bioinformatics — Posted on 2023-02-05
3381 FarmGTEx TWAS-server: an interactive web server for customized TWAS analysis in both human and farm animals
Zhang, Z.; Chen, Z.; Teng, J.; Liu, S.; Lin, Q.; Gao, Y.; Bai, Z.; The FarmGTEx Consortium, ; Li, B.; Liu, G.; Zhang, Z.; Pan, Y.; Zhang, Z.; Fang, L.; Wang, Q.
10.1101/2023.02.03.527092 — bioinformatics — Posted on 2023-02-05
3382 Nanostructured Hydrotropes Caged Cytochrome c with Boosted Stability in Harsh Environments: A Molecular Insights
Bharadwaj, P.; Sarkar, D. K.; Bisht, M.; Shet, S. M.; Nataraj, S. K.; Lokesh, V.; Franklin, G.; Brezovsky, J.; Mondal, D.
10.1101/2023.02.05.527166 — biochemistry — Posted on 2023-02-05
3383 Molecular evidence of anteroposterior patterning in adult echinoderms
Formery, L.; Peluso, P.; Kohnle, I.; Malnick, J.; Pitel, M.; Uhlinger, K.; Rokhsar, D. S.; Rank, D. R.; Lowe, C. J.
10.1101/2023.02.05.527185 — developmental biology — Posted on 2023-02-05
3385 Cultivation of the polyextremophile Cyanidioschyzon merolae 10D during summer conditions on the coast of the Red Sea and its adaptation to hypersaline sea water
Villegas, M. V.; Gonzalez-Portela, R. E.; Bastos de Freitas, B.; AlJahdali, A.; Romero-Villegas, G. I.; Abdulsalam, R.; Kapoore, R. V.; Fuentes-Grunewald, C.; Lauersen, K. J.
10.1101/2023.02.02.526792 — bioengineering — Posted on 2023-02-05
3386 Automated Agnostic Designation of Pathogen Lineages
McBroome, J.; de Bernardi Schneider, A.; Roemer, C.; Wolfinger, M. T.; Hinrichs, A. S.; O'Toole, A. N.; Ruis, C.; Turakhia, Y.; Rambaut, A.; Corbett-Detig, R.
10.1101/2023.02.03.527052 — evolutionary biology — Posted on 2023-02-05
3390 Metabolic engineering of Saccharomyces cerevisiae for second-generation ethanol production from xylo-oligosaccharides and acetate
Procopio, D. P.; Lee, J. W.; Shin, J.; Tramontina, R.; Avila, P. F.; Brenelli, L. B.; Squina, F. M.; Damasio, A.; Rabelo, S. C.; Goldbeck, R.; Franco, T. T.; Leak, D.; Jin, Y.-S.; Basso, T. O.
10.1101/2023.02.04.527128 — bioengineering — Posted on 2023-02-04
3391 An integrated map of cell type-specific gene expression in pancreatic islets
Elgamal, R.; Kudtarkar, P.; Melton, R.; Mummey, H.; Benaglio, P.; Okino, M.-L.; Gaulton, K. J.
10.1101/2023.02.03.526994 — genomics — Posted on 2023-02-04
3395 ncBAF, a chromatin remodeler, enhances PXR-mediated transcriptional activation in the human and mouse liver
Kurosawa, K.; Nakano, M.; Yokoseki, I.; Nagaoka, M.; Takemoto, S.; Sakai, Y.; Kobayashi, K.; Kazuki, Y.; Fukami, T.; Nakajima, M.
10.1101/2023.02.03.527063 — pharmacology and toxicology — Posted on 2023-02-04
3396 Identification and characterization of bacterial glycogen-degrading enzymes in the vaginal microbiome
Jenkins, D. J.; Woolston, B. M.; Hood-Pishchany, M. I.; Pelayo, P.; Konopask, A. N.; Peters, M. Q.; France, M.; Ravel, J.; Mitchell, C. M.; Rakoff-Nahoum, S.; Whidbey, C.; Balskus, E. P.
10.1101/2021.07.19.452977 — biochemistry — Posted on 2023-02-04
3397 Fecal virome transplantation is sufficient to alter fecal microbiota and drive lean and obese body phenotypes in mice
Borin, J. M.; Liu, R.; Wang, Y.; Wu, T.-C.; Chopyk, J.; Huang, L.; Kuo, P.; Ghose, C.; Meyer, J. R.; Tu, X. M.; Schnabl, B.; Pride, D. T.
10.1101/2023.02.03.527064 — microbiology — Posted on 2023-02-04
3398 Root cap cell corpse clearance limits microbial colonization
Charura, N. M.; Llamas, E.; De Quattro, C.; Vilchez, D.; Nowack, M. K.; Zuccaro, A.
10.1101/2023.02.03.526420 — plant biology — Posted on 2023-02-04
3401 Protein Sequence Design by Entropy-based Iterative Refinement
Zhou, X.; Chen, G.; Ye, J.; Wang, E.; Zhang, J.; Mao, C.; Li, Z.; Hao, J.; Huang, X.; Tang, J.; Heng, P. A.
10.1101/2023.02.04.527099 — bioinformatics — Posted on 2023-02-04
3402 Gene panel selection for targeted spatial transcriptomics
Zhang, Y.; Petukhov, V.; Biederstedt, E.; Kharchenko, P. V.
10.1101/2023.02.03.527053 — bioinformatics — Posted on 2023-02-04
3403 Metabolomic Phenotypes Reflect Patient Sex and Injury Status: A Cross-Sectional Analysis of Human Synovial Fluid
Welhaven, H. D.; Welfley, A. H.; Pershad, P.; Satalich, J.; O'Connell, R.; Bothner, B.; Vap, A. R.; June, R. K.
10.1101/2023.02.03.527040 — bioengineering — Posted on 2023-02-04
3404 Cultivation of the polyextremophile Cyanidioschyzon merolae 10D during summer conditions on the coast of the Red Sea and its adaptation to hypersaline sea water
Villegas, M. V.; Gonzalez-Portela, R. E.; Bastos de Freitas, B.; AlJahdali, A.; Romero-Villegas, G. I.; Abdulsalam, R.; Kapoore, R. V.; Fuentes-Grunewald, C.; Lauersen, K. J.
10.1101/2023.02.02.526792 — bioengineering — Posted on 2023-02-04
3405 An 8-cage imaging system for automated analyses of mouse behavior
Del Rosario Hernandez, T.; Joshi, N. R.; Gore, S. V.; Kreiling, J. A.; Creton, R.
10.1101/2023.02.04.527129 — animal behavior and cognition — Posted on 2023-02-04
3408 Spatiotemporal specification of human green and red cones
Hadyniak, S. E.; Eldred, K. C.; Brenerman, B.; Hussey, K. A.; Hagen, J. F. D.; McCoy, R. C.; Sauria, M. E. G.; Kuchenbecker, J. A.; Reh, T. A.; Glass, I.; Neitz, M.; Neitz, J.; Taylor, J.; Johnston, R. J.
10.1101/2021.03.30.437763 — developmental biology — Posted on 2023-02-04
3410 Establishment of beta cell heterogeneity via differential CpG methylation at Nnat
Yu, V.; Yong, F.; Chen, K.; Georgiadou, E.; Parveen, N.; Marta, A.; Khadayate, S.; Stamoulis, Z.; Marselli, L.; De Luca, C.; Suleiman, M.; Hatanaka, Y.; Montoya, A.; Elliott, J.; Patel, B.; Demchenko, N.; Whilding, C.; Hajkova, P.; Schliaha, P.; Kramer, H.; Ali, Y.; Marchetti, P.; Dhawan, S.; Withers, D. J.; Rutter, G. A.; Millership, S. J.
10.1101/2023.02.04.527050 — cell biology — Posted on 2023-02-04
3411 Ligament injury in adult zebrafish triggers ECM remodeling and cell dedifferentiation for scar-free regeneration
Anderson, T.; Mo, J.; Gagarin, E.; Sherwood, D.; Blumenkrantz, M.; Mao, E.; Leon, G.; Chen, H.-J.; Tseng, K.-C.; Fabian, P.; Crump, J. G.; Smeeton, J.
10.1101/2023.02.03.527039 — molecular biology — Posted on 2023-02-04
3413 Bumblebee mouthparts exhibit poor acuity for the detection of pesticides in nectar
Parkinson, R. H.; Scott, J.; Jones, H.; Dorling, A. L.; McDermott-Roberts, A. E.; Haslam, M.; Wright, G. A.
10.1101/2023.02.03.526956 — neuroscience — Posted on 2023-02-04
3414 Large-scale brain-wide neural recording in nonhuman primates
Trautmann, E. M.; Hesse, J. K.; Stine, G. M.; Xia, R.; Shude Zhu, S.; O'Shea, D. J.; Karsh, B.; Colonell, J.; Lanfranchi, F.; Vyas, S.; Zimnik, A.; Steinemann, N. A.; Wagenaar, D. A.; Andrei, A.; Mora Lopez, C.; OCallaghan, J. M.; Putzeys, J.; Raducanu, B. C.; Welkenhuysen, M.; Churchland, M.; Moore, T.; Shadlen, M. N.; Shenoy, K. V.; Tsao, D.; Dutta, B.; Harris, T.
10.1101/2023.02.01.526664 — neuroscience — Posted on 2023-02-04
3417 Clinically relevant concurrent BRAF and MEK inhibition alters differentiation states and sensitizes BRAF V600E-mutated high-grade gliomas to immune checkpoint blockade
Park, J.; Grossauer, S.; Wang, W.; Xing, Y. L.; Koeck, K.; Garcia, C. A.; Nasajpour, E.; Wilson, C.; Lancero, H.; Harter, P. N.; Filipski, K.; Daynac, M.; Meyer, L.; Guinle, M. I. B.; Monje, M.; Vogel, H.; Lim, M.; Prolo, L. M.; Grant, G. A.; Petritsch, C. K.
10.1101/2023.02.03.526065 — cancer biology — Posted on 2023-02-04
3420 Naive T lymphocytes chemotax to CCL21 but not to S1P-rich serum
Garcia Seyda, N.; Song, S.; David-Broglio, L.; Matti, C.; Artinger, M.; Pelicot-Biarnes, M.; Valignat, M.-P.; F. Legler, D.; Bajenoff, M.; Theodoly, O.
10.1101/2023.02.03.526993 — biophysics — Posted on 2023-02-04
3425 Casμ, a novel class of miniature type-V Cas12f nucleases with diverse PAM
Sharrar, A.; Arake de Tacca, L.; Collingwood, T.; Meacham, Z.; Rabuka, D.; Staples-Ager, J.; Schelle, M.
10.1101/2023.02.03.527072 — biochemistry — Posted on 2023-02-04
3428 Single-cell genomics reveals the divergent mitochondrial genomes of Retaria (Foraminifera and Radiolaria)
Macher, J.-N.; Coots, N. L.; Poh, Y.-P.; Girard, E. B.; Langerak, A.; Munoz-Gomez, S. A.; Sinha, S. D.; Jirsova, D.; Vos, R.; Wissels, R.; Gile, G. H.; Renema, W.; Wideman, J. G.
10.1101/2023.02.03.527036 — genomics — Posted on 2023-02-04
3429 Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate in aging fibroblasts
Zhou, W.; Karan, K.; Klein, H.-U.; Sturm, G.; De Jager, P.; Bennett, D. A.; Hirano, M.; Picard, M.; Mills, R.
10.1101/2023.02.03.527065 — genomics — Posted on 2023-02-04
3432 Host space, not energy or symbiont size, constrains feather mite abundance across passerine bird species
Labrador, M. d. M.; Serrano, D.; Dona, J.; Aguilera, E.; Arrollo, J. L.; Atienzar, F.; Barba, E.; Bermejo, A.; Blanco, G.; Borras, A.; Calleja, J. A.; Canto, J. L.; Cortes, V.; de la Puente, J.; de Palacio, D.; Fernandez-Gonzalez, S.; Figuerola, J.; Frias, O.; Fuertes-Marcos, B.; Garamszegi, L. Z.; Gordo, O.; Gurpegui, M.; Kovacs, I.; Martinez, J. L.; Melendez, L.; Mestre, A.; Moller, A. P.; Monros, J. S.; Moreno-Opo, R.; Navarro, C.; Pap, P. L.; Perez-Tris, J.; Piculo, R.; Ponce, C.; Proctor, H.; Rodriguez, R.; Sallent, A.; Senar, J. C.; Tella, J. L.; Vagasi, C. I.; Vogeli, M.; Jovani, R.
10.1101/2023.02.03.526976 — ecology — Posted on 2023-02-04
3433 One does not simply grow well: Performance of grassland plants in home and foreign soil and climate
Aares, K. H.; Bockelie-Rosendahl, T.; Priyadarshi, R.; Pugnaire, F. I.; Schob, C.; Alifriqui, M.; Manrique, E.; Jaakola, L. H.; Brathen, K. A.
10.1101/2023.02.03.526963 — ecology — Posted on 2023-02-04
3434 Transcriptomic profiling of tissue environments critical for post-embryonic patterning and morphogenesis of zebrafish skin
Aman, A. J.; Saunders, L. M.; Carr, A. A.; Srivatsan, S. R.; Eberhard, C.; Carrington, B.; Watkins-Chow, D. E.; Pavan, W.; Trapnell, C.; Parichy, D. M.
10.1101/2021.05.12.443782 — developmental biology — Posted on 2023-02-04
3437 Gardnerella Diversity and Ecology in Pregnancy and Preterm Birth
Berman, H. L.; Goltsman, D. S. A.; Anderson, M.; Relman, D. A.; Callahan, B. J.
10.1101/2023.02.03.527032 — microbiology — Posted on 2023-02-04
3438 High-level ceftazidime-avibactam resistance in Escherichia coli conferred by the novel plasmid-mediated beta-lactamase CMY-185 variant
Shropshire, W. C.; Endres, B. T.; Borjan, J.; Aitken, S. L.; Bachman, W. C.; McElheny, C. L.; Khan, A.; Bhatti, M. M.; Saharasbhojane, P.; Kawai, A.; Shields, R. K.; Shelburne, S. A.; Doi, Y.
10.1101/2023.02.03.527067 — microbiology — Posted on 2023-02-04
3439 Single molecule DNA methylation and hydroxymethylation reveal unique epigenetic identity profiles of T helper cells
Goldsmith, C.; Fesneau, O.; Thevin, V.; Matias, M. I.; Perrault, J.; Abid, A. H.; Taylor, N.; Dardalhon, V.; Marie, J. C.; Hernandez-Vargas, H.
10.1101/2023.02.03.527091 — immunology — Posted on 2023-02-04
3440 McLTP1, a lipid transfer protein isolated from noni seeds induces effective healing of superficial burns
Kurita, B. M.; Rangel, G. d. F. P.; Rabelo, L. M. A.; Souza, T. d. F. G.; Macedo, F. S.; Leitao, R. F. d. C.; Costa, A. S.; Oliveira, H. D. d.; Alencar, N. M. N. d.
10.1101/2023.02.04.527120 — immunology — Posted on 2023-02-04
3444 The representational geometry of cognitive maps under dynamic cognitive control
Park, S. A.; Zolfaghar, M.; Russin, J.; Miller, D. S.; O'Reilly, R. C.; Boorman, E. D.
10.1101/2023.02.04.527142 — neuroscience — Posted on 2023-02-04
3445 Adolescent neurostimulation of dopamine circuit reverses genetic deficits in frontal cortex function
Mastwal, S.; Li, X.; Stowell, R. D.; Manion, M.; Zhang, W.; Kim, N.-S.; Yoon, K.-J.; Song, H.; Ming, G.-L.; Wang, K. H.
10.1101/2023.02.03.526987 — neuroscience — Posted on 2023-02-04
3446 Long-term unsupervised recalibration of cursor BCIs
Wilson, G. H.; Willett, F. R.; Stein, E. A.; Kamdar, F.; Avansino, D. T.; Hochberg, L. R.; Shenoy, K. V.; Druckmann, S.; Henderson, J. M.
10.1101/2023.02.03.527022 — neuroscience — Posted on 2023-02-04
3447 Imaging Microglia Surveillance during Sleep-wake Cycles in Freely Behaving Mice
Gu, X.; Zhang, L.; Zhao, Z.; Fang, H.; Zhao, T.; Ju, S.; Chen, X.; Gao, W.; Qian, X.; Wang, X.; Zhang, J.; Cheng, H.
10.1101/2023.02.03.527083 — neuroscience — Posted on 2023-02-04
3450 Conflict during learning reconfigures the neural representation of positive valence and approach behaviour
Molina-Garcia, L.; Colinas-Fischer, S.; Benavides-Laconcha, S.; Lin, L.; Clark, E.; Garcia-Minaur-Ortiz, B.; Barrios, A.
10.1101/2023.02.03.527017 — neuroscience — Posted on 2023-02-04
3452 Early detection of white matter hyperintensities using SHIVA-WMH detector
Tsuchida, A.; Boutinaud, P.; Verrecchia, V.; Tzourio, C.; Debette, S.; Joliot, M.
10.1101/2023.02.03.526961 — neuroscience — Posted on 2023-02-04
3453 Effort cost of harvest affects decisions and movement vigor of marmosets during foraging
Hage, P.; Jang, I. K.; Looi, V.; Fakharian, M. A.; Orozco, S. P.; Sedaghat-Nejad, E.; Pi, J.; Shadmehr, R.
10.1101/2023.02.04.527146 — neuroscience — Posted on 2023-02-04
3455 Evolution of the jasmonate ligands and their biosynthetic pathways
Chini, A.; Monte, I.; Zamarreno, A.; Garcia Mina, J. M.; Solano, R.
10.1101/2023.02.03.526968 — plant biology — Posted on 2023-02-04
3456 EphrinA4/EphA4 controls blood pressure via arterial sympathetic innervation
SIMONNET, E.; MARTIN, S.; VILAR, J.; ROY-VESSIERES, E.; TAIB, S.; MONCEAU, V.; Pardanaud, L.; BOUBY, N.; Eichmann, A.; SILVESTRE, J.-S.; HENRION, D.; BRUNET, I. V.
10.1101/2023.02.03.526852 — physiology — Posted on 2023-02-04
3457 ncBAF, a chromatin remodeler, enhances PXR-mediated transcriptional activation in the human and mouse liver
Kurosawa, K.; Nakano, M.; Yokoseki, I.; Nagaoka, M.; Takemoto, S.; Sakai, Y.; Kobayashi, K.; Kazuki, Y.; Fukami, T.; Nakajima, M.
10.1101/2023.02.03.527063 — pharmacology and toxicology — Posted on 2023-02-04
3458 Cdc73 protects Notch-induced T-cell leukemia cells from DNA damage and mitochondrial stress
Melnick, A.; Liang, S.; Liu, Y.; Wang, Q.; Dean, N.; Choe, E.; Kunnath, N.; Bodanapu, G.; Mullin, C.; Akter, F.; Lin, K.; Magnuson, B.; Kumar, S.; Lombard, D. B.; Muntean, A. G.; Ljungman, M.; Sekiguchi, J.; Ryan, R. J. H.; Chiang, M. Y.
10.1101/2023.01.22.525059 — cancer biology — Posted on 2023-02-04
3461 Visualizing and exploring patterns of large mutational events with SigProfilerMatrixGenerator
Khandekar, A.; Vangara, R.; Barnes, M.; Diaz-Gay, M.; Abbasi, A.; Bergstrom, E. N.; Steele, C. D.; Pillay, N.; Alexandrov, L. B.
10.1101/2023.02.03.527015 — bioinformatics — Posted on 2023-02-04
3465 Welcome to the big leaves: best practices for improving genome annotation in non-model plant genomes
Vuruputoor, V. S.; Monyak, D.; Fetter, K. C.; Webster, C.; Zaman, S.; Bhattarai, A.; Bennett, J.; McEvoy, S.; Shrestha, B.; Caballero, M.; Wegrzyn, J.
10.1101/2022.10.03.510643 — bioinformatics — Posted on 2023-02-04
3467 Development of a Robust Consensus Modeling Approach for Identifying Cellular and Media Metabolites Predictive of Mesenchymal Stromal Cell Potency
Van Grouw, A.; Colonna, M. B.; Maughon, T. S.; Shen, X.; Larey, A. M.; Moore, S. G.; Carolyn, Y.; Facundo, F. M.; Arthur, E. S.; Stice, S. L.; Annie, B.-W. C.; Ross, M. A.
10.1101/2023.02.03.526990 — bioengineering — Posted on 2023-02-04
3469 OSCAR: an open-source controller for animal research
Dastin-van Rijn, E. M.; Sachse, E.; Iacobucci, F.; Mensinger, M.; Widge, A.
10.1101/2023.02.03.527033 — bioengineering — Posted on 2023-02-04
3471 Targeting fungal BET bromodomains as a pan-Candida antifungal strategy
Wei, K.; Overhulse, J. M.; Arlotto, M.; Zhou, Y.; Dupper, N. J.; Kashemirov, B. A.; Garnaud, C.; Bourgine, G.; Cornet, M.; Rabut, G.; McKenna, C. E.; Petosa, C.; Govin, J.
10.1101/2023.02.03.527073 — biochemistry — Posted on 2023-02-04
3475 Genetics of continuous colour variation in a pair of sympatric sulphur butterflies
Hanly, J. J.; Francescutti, C. M.; Loh, L. S.; Corning, O. B.; Long, D. J.; Nakatani, M. A.; Porter, A. H.; Martin, A.
10.1101/2023.02.03.526907 — genetics — Posted on 2023-02-04
3476 ORFanes in mitochondrial genomes of marine polychaete Polydora
Selifanova, M.; Demianchenko, O.; Noskova, E.; Pitikov, E.; Skvortsov, D.; Drozd, J.; Vatolkina, N.; Apel, P.; Kolodyazhnaya, E.; Ezhova, M. A.; Tzetlin, A. B.; Neretina, T. V.; Knorre, D. A.
10.1101/2023.02.04.527105 — evolutionary biology — Posted on 2023-02-04
3477 Elexacaftor/VX-445-mediated CFTR interactome remodeling reveals differential correction driven by mutation-specific translational dynamics
Kim, M.; McDonald, E. F.; Sabusap, C. M. P.; Timalsina, B.; Joshi, D.; Hong, J. S.; Rab, A.; Sorscher, E. J.; Plate, L.
10.1101/2023.02.04.527134 — cell biology — Posted on 2023-02-04
3480 Comparative multi-omics analyses of cardiac mitochondrial stress in three mouse models of frataxin deficiency
Sayles, N. M.; Napierala, J. S.; Anrather, J.; Diedhiou, N.; Li, J.; Napierala, M.; Puccio, H.; Manfredi, G.
10.1101/2023.02.03.526305 — molecular biology — Posted on 2023-02-04
3481 Sexual dimorphism and the multi-omic response to exercise training in rat subcutaneous white adipose tissue
Many, G. M.; Sanford, J. A.; Sagendorf, T. J.; Hou, Z.; Nigro, P.; Whytock, K. L.; Amar, D.; Caputo, T.; Gay, N. R.; Gaul, D. A.; Hirshman, M. F.; Jimenez-Morales, D.; Lindholm, M. E.; Muehlbauer, M. J.; Vamvini, M.; Bergman, B. C.; Fernandez, F. M.; Goodyear, L. J.; Ortlund, E. A.; Sparks, L. M.; Xia, A.; Adkins, J. N.; Bodine, S. C.; Newgard, C. B.; Schenk, S.; Study Group, T. M.
10.1101/2023.02.03.527012 — molecular biology — Posted on 2023-02-04
3482 Lung microenvironments harbor Mycobacterium tuberculosis phenotypes with distinct treatment responses
Walter, N. D.; Ernest, J. P.; Dide-Agossou, C.; Bauman, A. A.; Ramey, M. E.; Rossmassler, K.; Massoudi, L. M.; Pauly, S.; Al Mubarak, R.; Voskuil, M. I.; Kaya, F.; Sarathy, J. P.; Zimmerman, M. D.; Dartois, V.; Podell, B. K.; Savic, R. M.; Robertson, G. T.
10.1101/2023.02.03.527062 — microbiology — Posted on 2023-02-04
3483 A Structural Classification of the Variant Surface Glycoproteins of the African Trypanosome
Dakovic, S.; Zeelen, J. P.; Gkeka, A.; Chandra, M.; Foti, C.; van Straaten, M.; Vlachou, E. P.; Aresta-Branco, F.; Papavasiliou, F. N.; Verdi, J.; Stebbins, C. E.
10.1101/2023.02.04.525354 — microbiology — Posted on 2023-02-04
3484 Comprehensive and Comparative Transcriptional Profiling of the Cell Wall Stress Response in Bacillus subtilis
Zhang, Q.; Cornilleau, C.; Muller, R. R.; Meier, D.; Flores, P.; Guerin, C.; Wolf, D.; Fromion, V.; Carballido-Lopez, R.; Mascher, T.
10.1101/2023.02.03.526509 — microbiology — Posted on 2023-02-04
3487 A role for the Gram-negative outer membrane in bacterial shape determination
Fivenson, E. M.; Rohs, P. D.; Vettiger, A.; Sardis, M. F.; Torres, G.; Forchoh, A.; Bernhardt, T. G.
10.1101/2023.02.03.527047 — microbiology — Posted on 2023-02-04
3488 Bulk and Mosaic Deletions of Egfr Reveal Regionally Defined Gliogenesis in the Developing Mouse Forebrain
Zhang, X.; Xiao, G.; Johnson, C. A.; Cai, Y.; Horowitz, Z.; Mennicke, C.; Coffey, R.; Haider, M.; Threadgill, D. W.; Eliscu, R.; Oldham, M. C.; Greenbaum, A. C.; Ghashghaei, H. T.
10.1101/2022.12.10.519926 — neuroscience — Posted on 2023-02-04
3491 A new route for integron cassette dissemination among bacterial genomes
Loot, C.; Millot, G.; Richard, E.; Littner, E.; Vit, C.; Lemoine, F.; Cury, J.; Darracq, B.; Niault, T.; Lapaillerie, D.; Parissi, V.; Rocha, E. P.; Mazel, D.
10.1101/2022.09.11.507474 — genetics — Posted on 2023-02-04
3495 The Clustered Gamma Protocadherin Pcdhγc4 Isoform Regulates Cortical Interneuron Programmed Cell Death in the Mouse Cortex.
Mancia Leon, W. R.; Steffen, D. M.; Dale-Huang, F.; Rakela, B.; Breevoort, A.; Romero-Rodriguez, R.; Hasenstaub, A. R.; Stryker, M. P.; Weiner, J. A.; Alvarez-Buylla, A.
10.1101/2023.02.03.526887 — neuroscience — Posted on 2023-02-04
3496 A Prefrontal Neural Circuit for Maternal Behavioural Leaning in Mice
Tasaka, G.-i.; Hagihara, M.; Irie, S.; Kobayashi, H.; Inada, K.; Kihara, M.; Abe, T.; Miyamichi, K.
10.1101/2023.02.03.527077 — neuroscience — Posted on 2023-02-04
3497 Neanderthal Introgression Shaped Human Circadian Traits
Velazquez-Arcelay, K.; Colbran, L. L.; McArthur, E.; Brand, C. M.; Siemann, J. K.; McMahon, D. G.; Capra, J. A.
10.1101/2023.02.03.527061 — evolutionary biology — Posted on 2023-02-04
3499 Riluzole suppresses growth and enhances response to endocrine therapy in ER+ breast cancer
Olukoya, A. O.; Stires, H.; Bahnassy, S.; Persaud, S.; Guerra, Y.; Ranjit, S.; Ma, S.; Cruz, M. I.; Benitez, C.; Rozeboom, A. M.; Ceuleers, H.; Berry, D. L.; Jacobsen, B. M.; Raj, G. V.; Riggins, R. B.
10.1101/2020.07.30.227561 — cancer biology — Posted on 2023-02-04
3500 Drivers of genomic landscapes of differentiation across Populus divergence gradient
Shang, H.; Rendon-Anaya, M.; Paun, O.; Field, D. L.; Hess, J.; Vogl, C.; Liu, J.; Ingvarsson, P. K.; Lexer, C.; Leroy, T.
10.1101/2021.08.26.457771 — evolutionary biology — Posted on 2023-02-04
3501 Cross-movie prediction of individualized functional topography
Jiahui, G.; Feilong, M.; Nastase, S. A.; Haxby, J. V.; Gobbini, M. I.
10.1101/2022.11.21.517253 — neuroscience — Posted on 2023-02-04
3505 Deformed wings is an Atg8a-interacting protein that negatively regulates autophagy
Kolodziej, M.; Tsapras, P.; Konstantinou, A.; Cameron, A.; Promponas, V.; Nezis, I.
10.1101/2023.02.03.526972 — cell biology — Posted on 2023-02-04
3506 A Soluble Platelet-Derived Growth Factor Receptor-β Originates via Pre-mRNA Splicing in the Healthy Brain and is Differentially Regulated during Hypoxia and Aging
Payne, L. B.; Abdelazim, H.; Hoque, M.; Barnes, A.; Mironovova, Z.; Willi, C. E.; Darden, J. A.; Houk, C.; Sedovy, M. W.; Johnstone, S. R.; Chappell, J. C.
10.1101/2023.02.03.527005 — cell biology — Posted on 2023-02-04
3507 Role of the small protein Mco6 in the mitochondrial sorting and assembly machinery
Busto, J. V.; Mathar, H.; Steiert, C.; Schneider, E. F.; Straub, S. P.; Ellenrieder, L.; Song, J.; Stiller, S. B.; Lübbert, P.; Guiard, B.; den Brave, F.; Schulte, U.; Fakler, B.; Becker, T.; Wiedemann, N.
10.1101/2023.02.03.527057 — cell biology — Posted on 2023-02-04
3508 FDX1 regulates cellular protein lipoylation through direct binding to LIAS.
Dreishpoon, M.; Bick, N.; Petrova, B.; Warui, D. M.; Cameron, A.; Booker, S. J.; Kanarek, N.; Golub, T.; Tsvetkov, P.
10.1101/2023.02.03.526472 — cell biology — Posted on 2023-02-04
3509 The tyrosine phosphatase LAR acts as a receptor of the nidogen-tetanus toxin complex
Surana, S.; Villarroel-Campos, D.; Panzi, C.; Novoselov, S. S.; Richter, S.; Zanotti, G.; Schiavo, G.
10.1101/2023.02.03.526966 — cell biology — Posted on 2023-02-04
3510 Chemo-sEVs release in cisplatin-resistance ovarian cancer cells are regulated by the lysosomal function
Cerda-Troncoso, C.; Grünenwald, F.; Arias-Munoz, E.; Cavieres, V. A.; Caceres-Verschae, A.; Hernandez, S.; Gaete-Ramirez, B.; Alvarez-Astudillo, F.; Acuna, R. A.; Ostrowski, M.; Burgos, P. V.; Varas-Godoy, M.
10.1101/2023.02.03.526974 — cancer biology — Posted on 2023-02-04
3511 BCR-ABL promotes hematopoietic stem and progenitor cell formation in embryonic stem cells
Artus, J.; Zenych, A.; Simanic, I.; Desterke, C.; Clay, D.; Saim, S.; Ijjeh, Y.; de Souza, L. E. B.; Coignard, S.; Bennaceur-Griscelli, A.; Turhan, A. G.; Foudi, A.
10.1101/2023.02.03.526926 — cancer biology — Posted on 2023-02-04
3514 Using single-cell RNA sequencing to generate cell-type-specific split-GAL4 reagents throughout development
Chen, Y.-C. D.; Chen, Y.-C.; Rajesh, R.; Shoji, N.; Jacy, M.; Lacin, H.; Erclik, T.; Desplan, C.
10.1101/2023.02.03.527019 — developmental biology — Posted on 2023-02-04
3515 Cardiac Troponin I Directly Binds and Inhibits Mitochondrial ATP Synthase: a Noncanonical Role in the Post-Ischemic Heart
Elezaby, A.; Lin, A. J.; Vijayan, V.; Pokhrel, S.; Bechara, L. R.; Ostberg, N. P.; Queliconi, B. B.; Campos, J. C.; Ferreira, J. C.; Haileselassie, B.; Mochly-Rosen, D.
10.1101/2023.02.03.526715 — cell biology — Posted on 2023-02-04
3517 Early maturation and hyperexcitability is a shared phenotype of cortical neurons derived from different ASD-associated mutations
Hussein, Y.; Tripathi, U.; Choudhary, A.; Nayak, R.; Peles, D.; Rosh, I.; Rabinski, T.; Djamus, J.; Vatine, G.; Spiegel, R.; Garin-Shkolnik, T.; Stern, S.
10.1101/2022.11.02.514882 — neuroscience — Posted on 2023-02-04
3518 Optogenetic recruitment of hypothalamic corticotrophin-releasing-hormone (CRH) neurons reduces motivational drive
Mitchell, C. S.; Campbell, E. J.; Fisher, S. D.; Stanton, L. M.; Burton, N. J.; Pearl, A. J.; McNally, G. P.; Bains, J. S.; Füzsi, T.; Graham, B. A.; Manning, E. E.; Dayas, C. V.
10.1101/2023.02.03.527084 — neuroscience — Posted on 2023-02-04
3519 Regulation of parvalbumin interneuron plasticity by neuropeptide-encoding genes
Selten, M.; Bernard, C.; Hamid, F.; Hanusz-Godoy, A.; Oozeer, F.; Zimmer, C.; Marin, O.
10.1101/2023.02.03.527010 — neuroscience — Posted on 2023-02-04
3520 Mathematically mapping the network of cells in the tumor microenvironment
van Santvoort, M.; Lapuente-Santana, O.; Finotello, F.; van der Hoorn, P.; Eduati, F.
10.1101/2023.02.03.526946 — systems biology — Posted on 2023-02-04
3522 Single-cell RNA sequencing reveals dysregulated fibroblast subclusters in prurigo nodularis
Patel, J. R.; Joel, M. Z.; Lee, K. K.; Kambala, A.; Cornman, H.; Oladipo, O.; Taylor, M.; Deng, J.; Parthasarathy, V.; Cravero, K.; Marani, M.; Zhao, R.; Sankararam, S.; Li, R.; Pritchard, T.; Rebecca, V.; Kwatra, M. M.; Ho, W. J.; Dong, X.; Kang, S.; Kwatra, S. G.
10.1101/2023.01.29.526050 — bioinformatics — Posted on 2023-02-04
3523 IQMMA: an efficient MS1 intensity extraction using multiple feature detection algorithms for DDA proteomics
Postoenko, V. I.; Garibova, L. A.; Levitsky, L. I.; Bubis, J. A.; Gorshkov, M. V.; Ivanov, M. V.
10.1101/2023.02.03.526776 — bioinformatics — Posted on 2023-02-04
3525 A genetic and linguistic analysis of the admixture histories of the islands of Cabo Verde
Laurent, R.; Szpiech, Z. A.; da Costa, S. S.; Thouzeau, V.; Fortes-Lima, C. A.; Dessarps-Freichey, F.; Lemee, L.; Utge, J.; Rosenberg, N. A.; Baptista, M.; Verdu, P.
10.1101/2022.04.11.487833 — genetics — Posted on 2023-02-03
3527 MICA: A multi-omics method to predict gene regulatory networks in early human embryos
Alanis-Lobato, G.; Bartlett, T. E.; Huang, Q.; Simon, C.; McCarthy, A.; Elder, K.; Snell, P.; Christie, L.; Niakan, K.
10.1101/2023.02.03.527081 — developmental biology — Posted on 2023-02-03
3528 Th1 cells alter the inflammatory signature of IL-6 by channeling STAT transcription factors to Alu-like retroelements
Millrine, D.; Cardus Figueras, A.; Uceda Fernandez, J.; Andrews, R.; Szomolay, B.; Cossins, B. C.; Rice, C.; Li, J.; Tyrrell, V.; mcLeod, L.; Holmans, P.; O'Donnell, V.; Taylor, P.; Turner, S. J.; Jenkins, B. J.; Jones, G. W.; Topley, N.; Williams, N. M.; Jones, S. A.
10.1101/2022.07.18.499157 — immunology — Posted on 2023-02-03
3529 Leptin antagonism improves Rett syndrome phenotype in symptomatic male Mecp2-null mice.
Belaidouni, Y.; Diabira, D.; Brosset-Heckel, M.; Valsamides, V.; Graziano, J.-C.; Santos, C.; Menuet, C.; Wayman, G.; Gaiarsa, J.-L.
10.1101/2023.02.03.526251 — neuroscience — Posted on 2023-02-03
3530 Effects of combined use of alcohol and delta-9-tetrahydrocannibinol on working memory in Long Evans rats
Carrica, L. K.; Choi, J.; Walter, F.; Noonan, B. L.; Shi, L.; Johnson, C. T.; Bradshaw, H. B.; Liang, N.-C.; Gulley, J. M.
10.1101/2023.02.02.526698 — neuroscience — Posted on 2023-02-04
3531 In vivo photopharmacology with light-activated opioid drugs
McClain, S. P.; Ma, X.; Johnson, D. A.; Johnson, C. A.; Layden, A. E.; Yung, J. C.; Lubejko, S. T.; Livrizzi, G.; He, X. J.; Zhou, J.; Ventriglia, E.; Rizzo, A.; Levinstein, M.; Gomez, J. L.; Bonaventura, J.; Michaelides, M.; Banghart, M. R.
10.1101/2023.02.02.526901 — neuroscience — Posted on 2023-02-04
3532 Spatio-temporal coordination at the maternal-fetal interface promotes trophoblast invasion and vascular remodeling in the first half of human pregnancy
Greenbaum, S.; Averbukh, I.; Soon, E.; Rizzuto, G.; Baranski, A.; Greenwald, N.; Kagel, A.; Bosse, M.; Jaswa, E. G.; Khair, Z.; Kwok, S.; Warshawsky, S.; Piyadasa, H.; Miller, G.; Schwartz, M.; Graf, W.; Van Valen, D.; Winn, V. D.; Hollmann, T.; Keren, L.; van de Rijn, M.; Angelo, M.
10.1101/2021.09.08.459490 — systems biology — Posted on 2023-02-03
3533 SOS2 regulates the threshold of mutant EGFR-dependent oncogenesis
Theard, P. L.; Linke, A. J.; Sealover, N. E.; Daley, B. R.; Yang, J.; Cox, K.; Kortum, R. L.
10.1101/2023.01.20.524989 — cancer biology — Posted on 2023-02-03
3535 Enhancing the anti-tumor efficacy of Bispecific T cell engagers via cell surface glycocalyx editing
Yang, Z.; Grande, G.; Hou, Y.; Wang, C.; Shi, Y.; Zak, J.; Cho, J. H.; Liu, D.; Teijaro, J.; Lerner, R. A.; Wu, P.
10.1101/2022.05.22.492978 — cancer biology — Posted on 2023-02-03
3536 In situ modeling of acquired resistance to RTK/RAS pathway targeted therapies
Sealover, N. E.; Theard, P. L.; Linke, A. J.; Hughes, J. M.; Daley, B. R.; Kortum, R. L.
10.1101/2023.01.27.525958 — cancer biology — Posted on 2023-02-03
3537 Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE
Chongsaritsinsuk, J.; Steigmeyer, A. D.; Mahoney, K. E.; Rosenfeld, M. A.; Lucas, T. M.; Ince, D.; Kearns, F. L.; Battison, A. S.; Hollenhorst, M. A.; Shon, J.; Tiemeyer, K. H.; Attah, V.; Kwon, C.; Bertozzi, C. R.; Ferracane, M. J.; Amaro, R. E.; Malaker, S. A.
10.1101/2023.02.01.526488 — cancer biology — Posted on 2023-02-03
3538 In situ architecture of Opa1-dependent mitochondrial cristae remodeling
Fry, M. Y.; Navarro, P. P.; Qin, X.; Inde, Z.; Ananda, V. Y.; Lugo, C. M.; Hakim, P.; Luce, B. E.; Ge, Y.; McDonald, J. L.; Ali, I.; Ha, L. L.; Kleinstiver, B. P.; Chan, D. C.; Sarosiek, K.; Chao, L. H.
10.1101/2023.01.16.524176 — biophysics — Posted on 2023-02-03
3542 Delineating genotypes and phenotypes of individual cells from long-read single cell transcriptomes
Shiau, C.-k.; Lu, L.; Kieser, R.; Fukumura, K.; Pan, T.; Lin, H.-Y.; Yang, J.; Tong, E. L.; Lee, G.; Yan, Y.; Huse, J.; Gao, R.
10.1101/2023.01.24.525264 — bioinformatics — Posted on 2023-02-03
3546 LDLR-mediated targeting and productive uptake of siRNA-peptide ligand conjugates in vitro and in vivo
Broc, B.; Varini, K.; Sonnette, R.; Pecqueux, B.; Benoist, F.; Thomas, M.; Masse, M.; Mechioukhi, Y.; Ferracci, G.; David, M.; Temsamani, J.; Khrestchatisky, M.; Jacquot, G.; Lecorche, P.
10.1101/2023.02.03.526778 — biochemistry — Posted on 2023-02-03
3548 Plant diversity in diet of Costa Rican Primates in contrasting habitats: a meta-analysis
Chaves, O. M.; Morales-Cerdas, V.; Calderon-Quiros, J.; Azofeifa-Rojas, I.; Riba-Hernandez, P.; Solano-Rojas, D.; Chaves-Cordero, C.; Chacon-Madrigal, E.; Melin, A. D.
10.1101/2023.02.02.526906 — animal behavior and cognition — Posted on 2023-02-03
3549 RTCpredictor: Identification of Read-Through Chimeric RNAs from RNA Sequencing Data
Singh, S.; Shi, X.; Ahmad, S.; Manley, T.; Piczak, C.; Phung, C.; Sun, Y.; Lynch, S.; Sharma, A.; Li, H.
10.1101/2023.02.02.526869 — genomics — Posted on 2023-02-03
3550 Spatially resolved multiomics of human cardiac niches
Kanemaru, K.; Cranley, J.; Muraro, D.; Miranda, A. M. A.; Pett, J. P.; Litvinukova, M.; Kumasaka, N.; Ho, S. Y.; Polanski, K.; Richardson, L.; Mach, L.; Dabrowska, M.; Richoz, N.; Barnett, S. N.; Perera, S.; Wilbrey-Clark, A. L.; Talavera-Lopez, C.; Mulas, I.; Mahbubani, K. T.; Bolt, L.; Mamanova, L.; Tuck, L.; Wang, L.; Huang, M. M.; Prete, M.; Pritchard, S.; Dark, J.; Saeb-Parsy, K.; Patel, M.; Clatworthy, M. R.; Hübner, N.; Chowdhury, R. A.; Noseda, M.; Teichmann, S. A.
10.1101/2023.01.30.526202 — genomics — Posted on 2023-02-03
3551 Integrative single-cell meta-analysis reveals disease-relevant vascular cell states and markers in human atherosclerosis
Mosquera, J. V.; Auguste, G.; Wong, D.; Turner, A. W.; Hodonsky, C. J.; Lino Cardenas, C. L.; Theofilatos, K.; Bos, M.; Kavousi, M.; Peyser, P.; Mayr, M.; Kovacic, J. C.; Bjorkegren, J. L. M.; Malhotra, R.; van der Laan, S. W.; Zang, C.; Sheffield, N.; Miller, C. L.
10.1101/2022.10.24.513520 — genomics — Posted on 2023-02-03
3552 A randomized multiplex CRISPRi-Seq approach for the identification of critical combinations of genes
Ellis, N. A.; Myers, K. S.; Tung, J.; Davidson Ward, A.; Johnston, K.; Bonnington, K. E.; Donohue, T. J.; Machner, M. P.
10.1101/2023.02.03.527066 — genetics — Posted on 2023-02-03
3555 Part-night exposure to artificial light at night has more detrimental effects on aphid colonies than fully lit nights
Heinen, R.; Sanchez-Mahecha, O.; Bezemer, T. M.; Dominoni, D. M.; Knappe, C.; Kollmann, J.; Kopatsch, A.; Pfeiffer, Z. A.; Schloter, M.; Sturm, S.; Schnitzler, J. P.; Vlot, A. C.; Weisser, W. W.
10.1101/2022.10.24.513514 — ecology — Posted on 2023-02-03
3558 An ULK1/2-PXN mechanotransduction complex suppresses breast cancer cell migration
Liang, P.; Zhang, J.; Wu, Y.; Zheng, S.; Xu, Z.; Yang, S.; Wang, J.; Ma, S.; Xiao, L.; Wu, T.; Jiang, W.; Xing, Q.; Kundu, M.; Wang, B.
10.1101/2023.02.03.526950 — cell biology — Posted on 2023-02-03
3559 Mechanotransductive feedback control of endothelial cell motility and vascular morphogenesis
Mason, D. E.; Goeckel, M.; Vega, S. L.; Wu, P.-H.; Johnson, D.; Heo, S.-J.; Wirtz, D.; Burdick, J. A.; Wood, L.; Chow, B. Y.; Stratman, A. N.; Boerckel, J. D.
10.1101/2022.06.15.496293 — cell biology — Posted on 2023-02-03
3561 Indoline CD4-mimetic Compounds Mediate Potent and Broad HIV-1 Inhibition and Sensitization to Antibody-dependent Cellular Cytotoxicity
Fritschi, C. J.; Anang, S.; Gong, Z.; Mohammadi, M.; Richard, J.; Bourassa, C.; Severino, K. T.; Richter, H.; Yang, D.; Chen, H.-C.; Chiu, T.-J.; Seaman, M.; Madani, N.; Abrams, C.; Finzi, A.; Hendrickson, W. A.; Sodroski, J.; Smith, A. B.
10.1101/2023.01.02.522483 — microbiology — Posted on 2023-02-03
3563 DIETARY PROTECTION AGAINST THE VISUAL AND MOTOR DEFICITS INDUCED BY EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS
Zyla-Jackson, K.; Walton, D. A.; Plafker, K. S.; Kovats, S.; Georgescu, C.; Brush, R. S.; Tytanic, M.; Agbaga, M.-P.; Plafker, S. M.
10.1101/2022.07.13.499958 — immunology — Posted on 2023-02-03
3564 UVB modifies skin immune-stroma cross-talk and promotes effector T cell recruitment during cryptic Leishmania donovani infection
Montes de Oca, M.; Dey, S.; Van Bocxlaer, K.; Ashwin, H.; Brown, N.; Myburgh, E.; Dey, N. S.; Rani, G. F.; Muscutt, E.; Osman, M.; Perez-Mazliah, D.; James, S.; Gilbert, L.; Chatterjee, M.; Kaye, P.
10.1101/2023.02.03.526940 — immunology — Posted on 2023-02-03
3566 Experience-Dependent Plasticity in Nucleus Laminaris of the Barn Owl
Carr, C. E.; Wang, T.; Kraemer, I.; Kuokkanen, P. T.; Capshaw, G.; Ashida, G.; Kempter, R.; Koeppl, C.
10.1101/2023.02.02.526884 — neuroscience — Posted on 2023-02-03
3570 Goal-seeking compresses neural codes for space in the human hippocampus and orbitofrontal cortex
Muhle-Karbe, P. S.; Sheahan, H.; Pezzulo, G.; Spiers, H. J.; Chien, S.; Schuck, N. W.; Summerfield, C.
10.1101/2023.01.12.523762 — neuroscience — Posted on 2023-02-03
3573 Phenelzine-based probes reveal Secernin-3 is involved in thermal nociception
Bustin, K. A.; Shishikura, K.; Chen, I.; Lin, Z.; McNight, N.; Chang, Y.; Wang, X.; Pei, L.; Lin, J. J.; Arellano, E.; Morton, P. D.; Gregus, A. M.; Buczynski, M. W.; Matthews, M. L.
10.1101/2023.02.02.526866 — neuroscience — Posted on 2023-02-03
3578 Systematic identification of structure-specific protein-protein interactions
Holfeld, A.; Schuster, D.; Sesterhenn, F.; Stalder, P.; Haenseler, W.; Barrio-Hernandez, I.; Ghosh, D.; Vowles, J.; Cowley, S. A.; Nagel, L.; Khanppnavar, B.; Beltrao, P.; Korkhov, V. M.; Riek, R.; de Souza, N.; Picotti, P.
10.1101/2023.02.01.522707 — systems biology — Posted on 2023-02-03
3580 Consensus tissue domain detection in spatial -omics data using MILWRM
Kaur, H.; Heiser, C. N.; McKinley, E. T.; Antunes, L. V.; Harris, C. R.; Roland, J. T.; Shrubsole, M. J.; Coffey, R. J.; Lau, K.; Vandekar, S. N.
10.1101/2023.02.02.526900 — systems biology — Posted on 2023-02-03
3581 Interactional roles in research meetings: a combined conversation analytic and quantitative network approach
Bet, M. D. A.; Antvelink, A. R.; van der Burgt, S. M. E.; Peerdeman, S. M.; Geurts, J. J. G.; Lamerichs, J.; Douw, L.
10.1101/2022.11.15.516566 — scientific communication and education — Posted on 2023-02-03
3582 Reduced motoneuron excitability and common synaptic inputs of the aged human vastus lateralis
Guo, Y.; Jones, E. J.; Skarabot, J.; Inns, T.; Phillips, B. E.; Atherton, P. J.; Piasecki, M.
10.1101/2023.02.03.526933 — physiology — Posted on 2023-02-03
3583 RAB7 deficiency impairs pulmonary artery endothelial function and promotes pulmonary hypertension
Piper, B.; Bogamuwa, S.; Hossain, T.; Farkas, D.; Rosas, L.; Green, A.; Newcomb, G.; Sun, N.; Horowitz, J. C.; Bhagwani, A. R.; Yang, H.; Kudryashova, T. V.; Rojas, M.; Mora, A. L.; Yan, P.; Mallampalli, R. K.; Goncharova, E. A.; Eckmann, D. M.; Farkas, L.
10.1101/2023.02.03.526842 — physiology — Posted on 2023-02-03
3584 Identifying Human Specific Adverse Outcome Pathways of Per- and Polyfluoroalkyl Substances Using Liver-Chimeric Humanized Mice
Robarts, D. R.; Paine-Cabrera, D.; Kotulkar, M.; Venneman, K. K.; Gunewardena, S.; Corton, J. C.; Lau, C.; Foquet, L.; Bial, G.; Apte, U.
10.1101/2023.02.01.526711 — pharmacology and toxicology — Posted on 2023-02-03
3585 An Innovative Non-Hormonal Strategy Targeting Redox Active Metals to Down-Regulate Estrogen-, Progesterone-, Androgen- and Prolactin-Receptors in Breast Cancer
Shehadeh-Tout, F.; Milioli, H. H.; Roslan, S.; Jansson, P. J.; Dharmasivam, M.; Graham, D.; Anderson, R.; Wijesinghe, T.; Azad, M. G.; Richardson, D. R.; Kovacevic, Z.
10.1101/2023.02.02.526543 — cancer biology — Posted on 2023-02-03
3586 IDHwt glioblastomas can be stratified by their transcriptional response to standard treatment, with implications for targeted therapy
Tanner, G.; Barrow, R.; Finetti, M.; Ajaib, S.; Ahmed, N.; Pollock, S.; Rippaus, N.; Bruns, A. F.; Syed, K.; Poulter, J.; Wilson, E. A.; Johnson, C. A.; Varn, F. S.; Bruning-Richardson, A.; Hogg, C.; Droop, A.; Gusnanto, A.; Care, M.; Cutillo, L.; Westhead, D. R.; Short, S.; Jenkinson, M.; Brodbelt, A.; Chakrabarty, A.; Ismail, A.; Verhaak, R. G.; Stead, L. F.
10.1101/2023.02.03.526945 — cancer biology — Posted on 2023-02-03
3587 Artificial channel separation of monochrome multi-structure microscopy image
Jin, L.; Liu, J.; Zhang, H.; Zhu, Y.; Yang, H.; Wang, J.; Zhang, L.; Xu, Y.
10.1101/2023.02.03.526797 — biophysics — Posted on 2023-02-03
3590 Label-free tumor cells classification using deep learning and high-content imaging
Piansaddhayanon, C.; Koracharkornradt, C.; Laosaengpha, N.; Tao, Q.; Ingrungruanglert, P.; Israsena, N.; Chuangsuwanich, E.; Sriswasdi, S.
10.1101/2023.02.03.526929 — bioinformatics — Posted on 2023-02-03
3592 Discovering highly potent antimicrobial peptides with deep generative model HydrAMP
Szymczak, P.; Mozejko, M.; Grzegorzek, T.; Jurczak, R.; Bauer, M.; Neubauer, D.; Sikora, K.; Michalski, M.; Sroka, J.; Setny, P.; Kamysz, W.; Szczurek, E.
10.1101/2022.01.27.478054 — bioinformatics — Posted on 2023-02-03
3593 FAVA: High-quality functional association networks inferred from scRNA-seq and proteomics data
Koutrouli, M.; Lindez, P. P.; Bouwmeester, R.; Rasmussen, S.; Martens, L.; Jensen, L. J.
10.1101/2022.07.06.499022 — bioinformatics — Posted on 2023-02-03
3596 Combined multiphoton microscopy and somatostatin receptor type 2 imaging of pancreatic neuroendocrine tumors
Daigle, N.; Knapp, T.; Duan, S.; Jones, D. W.; Azhdarinia, A.; Ghosh, S. C.; AghaAmiri, S.; Ikoma, N.; Estrella, J. S.; Schnermann, M. J.; Merchant, J. L.; Sawyer, T. W.
10.1101/2023.02.03.526958 — bioengineering — Posted on 2023-02-03
3597 The double-drift illusion biases the marmoset oculomotor system
Dotson, N. M.; Davis, Z. W.; Salisbury, J. M.; Palmer, S. E.; Cavanagh, P.; Reynolds, J.
10.1101/2023.02.02.526908 — animal behavior and cognition — Posted on 2023-02-03
3599 Multi-response Mendelian randomization: Identification of shared and distinct exposures for multimorbidity and multiple related disease outcomes
Zuber, V.; Lewin, A.; Levin, M.; Haglund, A.; Gonzalez, S. B.-A.; Emanueli, C.; Damrauer, S.; Burgess, S.; Gill, D.; Bottolo, L.
10.1101/2023.02.01.526689 — genetics — Posted on 2023-02-03
3601 The Soil Food Web Ontology: aligning trophic groups, processes, and resources to harmonise and automatise soil food web reconstructions
Le Guillarme, N.; Hedde, M.; Potapov, A.; Berg, M. P.; Briones, M. J. I.; Calderon-Sanou, I.; Hohberg, K.; Martinez Almoyna, C.; Martinez-Munoz, C. A.; Pey, B.; Russell, D.; Thuiller, W.
10.1101/2023.02.03.526812 — ecology — Posted on 2023-02-03
3602 Widespread reductions in body size are paired with stable assemblage biomass.
Martins, I. S.; Schrodt, F.; Blowes, S. A.; Bates, A. E.; Bjorkman, A. D.; Brambilla, V.; Carvajal-Quintero, J.; Chow, C. F. Y.; Daskalova, G. N.; Edwards, K.; Eisenhauer, N.; Field, R.; Fontrodona-Eslava, A.; Henn, J. J.; van Klink, R.; Madin, J. S.; Magurran, A. E.; McWilliam, M. J.; Moyes, F.; Pugh, B.; Sagouis, A.; Trindade-Santos, I.; McGill, B. J.; Chase, J. M.; Dornelas, M.
10.1101/2023.02.03.526822 — ecology — Posted on 2023-02-03
3605 Microbiome induced complement synthesized in the gut protects against enteric infections
Wu, M.; Zheng, W.; Song, X.; Bao, B.; Wang, Y.; Ramanan, D.; Yang, D.; Liu, R.; Macbeth, J. C.; Do, E. A.; Andrade, W. A.; Yang, T.; Cho, H.-S.; Gazzaniga, F. S.; Ilves, M.; Coronado, D.; Thompson, C.; Hang, S.; Chiu, I. M.; Moffitt, J. R.; Hsiao, A.; Mekalanos, J. J.; Benoist, C.; Kasper, D. L.
10.1101/2023.02.02.523770 — immunology — Posted on 2023-02-03
3607 BCR-induced protein dynamics and the emerging role of SUMOylation revealed by proximity proteomics
Awoniyi, L. O.; Sarapulov, A. V.; Hernandez-Perez, S.; Runsala, M.; Cunha, D. M.; Tejeda-Gonzalez, B.; Sustar, V.; Balci, M. O.; Petrov, P.; Mattila, P. K.
10.1101/2020.09.29.318766 — immunology — Posted on 2023-02-03
3608 Erasable Hippocampal Neural Signatures Predict Memory Discrimination
Kinsky, N. R.; Orlin, D. O.; Ruesch, E. A.; Diba, K.; Ramirez, S.
10.1101/2023.02.02.526824 — neuroscience — Posted on 2023-02-03
3610 Folate-based in vivo reprogramming of dentate gyrus improves cognitive function in old mice
Anton Fernandez, A.; Cuadros, R.; Peinado-Cahuchola, R.; Hernandez, F.; Avila, J.
10.1101/2023.02.01.526619 — neuroscience — Posted on 2023-02-03
3611 Social affective behaviors among female rats involve the basolateral amygdala and insular cortex
Djerdjaj, A.; Rieger, N. S.; Brady, B. H.; Carey, B. N.; Ng, A. J.; Christianson, J. P.
10.1101/2023.02.02.526780 — neuroscience — Posted on 2023-02-03
3614 Associations between regular cannabis use and brain resting-state functional connectivity in adolescents and adults
Ertl, N.; Lawn, W.; Mokrysz, C.; Freeman, T.; Alnagger, N.; Borissova, A.; Fernandez-Vinson, N.; Lees, R.; Ofori, S.; Petrilli, K.; Trinci, K.; Viding, E.; Curran, H. V.; Wall, M. B.
10.1101/2022.08.24.505069 — neuroscience — Posted on 2023-02-03
3615 The DUSP1 on CaMKII-positive neurons in mPFC mediates adolescent cocaine exposure-induced higher sensitivity to cocaine during adulthood
Wei, X.; Chang, J.; Cheng, Z.; Chen, W.; Guo, H.; Liu, Z.; Mai, Y.; Hu, T.; Zhang, Y.; Cai, Q.; Ge, F.; Fan, Y.; Guan, X.
10.1101/2022.08.26.505502 — neuroscience — Posted on 2023-02-03
3618 spongEffects: ceRNA modules offer patient-specific insights into the miRNA regulatory landscape
Boniolo, F.; Hoffmann, M.; Roggendorf, N.; Tercan, B.; Baumbach, J.; Castro, M.; Robertson, A. G.; Saur, D.; List, M.
10.1101/2022.03.29.486212 — systems biology — Posted on 2023-02-03
3619 Beyond the foliage: Using non-destructive multimodal 3D imaging and AI to phenotype and diagnose trunk diseases
Fernandez, R.; Le Cunff, L.; Merigeaud, S.; Verdeil, J.-L.; Perry, J.; Larignon, P.; Spilmont, A.-S.; Chatelet, P.; Cardoso, M.; Goze-Bac, C.; Moisy, C.
10.1101/2022.06.09.495457 — plant biology — Posted on 2023-02-03
3620 The Medicago truncatula nodule-specific cysteine-rich peptides, NCR343 and NCR-new35 are required for the maintenance of rhizobia in nitrogen-fixing nodules.
Horvath, B.; Gungor, B.; Toth, M.; Domonkos, A.; Ayaydin, F.; Saifi, F.; Chen, Y.; Biro, J. B.; Bourge, M.; Szabo, Z.; Toth, Z.; Chen, R.; Kalo, P.
10.1101/2023.01.23.523609 — plant biology — Posted on 2023-02-03
3621 Xenopus laevis lack the critical sperm factor PLCζ
Bainbridge, R. E.; Rosenbaum, J. C.; Sau, P.; Carlson, A. E.
10.1101/2023.02.02.526858 — physiology — Posted on 2023-02-03
3622 Effects of Aerobic Exercise in Hepatic Lipid Droplet-Mitochondria interaction in Non-alcoholic Fatty Liver Disease
Borquez, J. C.; Diaz-Castro, F.; Pino-de la Fuente, F.; Espinoza, K.; Figueroa, A. M.; Martinez-Ruiz, I.; Hernandez, V.; Lopez-Soldado, I.; Ventura, R.; Espinosa, A.; Cortes, V.; Hernandez-Alvarez, M. I.; Troncoso, R.
10.1101/2023.01.31.526481 — physiology — Posted on 2023-02-03
3623 Thermal conditioning of quail embryos has transgenerational and reversible long-term effects
Vitorino Carvalho, A.; Hennequet-Antier, C.; Rouger, R.; Delaveau, J.; Bordeau, T.; Crochet, S.; Courousse, N.; Pitel, F.; Collin, A.; Coustham, V.
10.1101/2023.02.02.526800 — physiology — Posted on 2023-02-03
3624 Adipocyte lipin 1 is positively associated with metabolic health in humans and regulates systemic metabolism in mice.
LaPoint, A.; Singer, J. M.; Ferguson, D.; Shew, T. M.; RenKemeyer, K.; Palacios, H.; Field, R.; Shankaran, M.; Smith, G. I.; Yoshino, J.; He, M.; Patti, G. J.; Hellerstein, M.; Klein, S.; Brestoff, J. R.; Finck, B.; Lutkewitte, A. J.
10.1101/2023.02.01.526676 — physiology — Posted on 2023-02-03
3625 NADK Isoform 3 promotes oxidative stress resistance and melanoma metastasis
Piskounova, E.; Cascio, G.; Aguirre, K.; Church, K.; Hughes, R. O.; Nease, L.; Licona, D. Q.; Delclaux, I.; Zerhouni, M.
10.1101/2023.02.02.526506 — cancer biology — Posted on 2023-02-03
3626 CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon restoration of RB function in malignant peripheral nerve sheath tumors
Wang, J.; Calizo, A.; Zhang, L.; Pino, J. C.; Lyu, Y.; Pollard, K.; Zhang, X.; Larsson, A. T.; Conniff, E.; Llosa, N.; Wood, D. K.; Largaespada, D. A.; Moody, S. E.; Gosline, S. J.; Hirbe, A. C.; Pratilas, C. A.
10.1101/2023.02.02.526674 — cancer biology — Posted on 2023-02-03
3627 Monitoring plasma nucleosome concentrations to measure of disease response and progression in dogs with hematopoietic malignancies.
Wilson-Robles, H.; Warry, E.; Miller, T.; Jarvis, J.; Matsushita, M.; Miller, P.; Herzog, M.; Turatsinze, J.-V.; Kelly, T. K.; Butera, T. K.; Michel, G.
10.1101/2023.02.02.526779 — cancer biology — Posted on 2023-02-03
3635 Novel integrated computational AMP discovery approaches highlight diversity in the helminth AMP repertoire
Irvine, A.; Mckenzie, D.; McCoy, C. J.; Graham, R.; Graham, C.; Huws, S. A.; Atkinson, L. E.; Mousley, A.
10.1101/2023.02.02.526830 — bioinformatics — Posted on 2023-02-03
3637 Rosuvastatin-Eluting Gold Nanoparticle-Loaded Perivascular Implantable Wrap for Enhanced Arteriovenous Fistula Maturation in a Murine Model
Klusman, C.; Martin, B.; Perez, J. V. D.; Barcena, A. J. R.; Bernardino, M. R.; San Valentin, E. M. D.; Damasco, J. A.; Del Mundo, H. C.; Court, K.; Godin, B.; Fowlkes, N.; Bouchard, R. R.; Cheng, J.; Huang, S. Y.; Melancon, M. P.
10.1101/2023.02.02.526859 — bioengineering — Posted on 2023-02-03
3638 An unbiased, automated platform for scoring dopaminergic neurodegeneration in C. elegans
Clark, A. S.; Kalmanson, Z.; Morton, K.; Hartman, J.; Meyer, J.; San-Miguel, A.
10.1101/2023.02.02.526781 — bioengineering — Posted on 2023-02-03
3639 Lung viral infection modelling in a bioengineered whole-organ
Tommasini, F.; Benoist, T.; Shibuya, S.; Woodall, M. N. J.; Naldi, E.; Orr, J. C.; Giobbe, G. G.; Maughan, E. F.; Hynds, R. E.; Gjinovci, A.; Hutchinson, J. C.; Arthurs, O. J.; Janes, S. M.; Elvassore, N.; Smith, C. M.; Michielin, F.; Pellegata, A. F.; De Coppi, P.
10.1101/2023.02.01.526441 — bioengineering — Posted on 2023-02-03
3645 PhylteR: efficient identification of outlier sequences in phylogenomic datasets
Comte, A.; Tricou, T.; Tannier, E.; Joseph, J.; Siberchicot, A.; Penel, S.; Allio, R.; Delsuc, F.; Dray, S.; de Vienne, D. M.
10.1101/2023.02.02.526888 — evolutionary biology — Posted on 2023-02-03
3648 A Novel MHC-Independent Mechanism of Tumor Cell Killing by CD8+ T Cells
Lerner, E. C.; Woroniecka, K.; D'Anniballe, V.; Wilkinson, D.; Lorrey, S.; Polania, J. W.; Wachsmuth, L.; Miggelbrink, A.; Raj, J.; Tomaszewski, W.; Mohan, A.; Cui, X.; Khasraw, M.; Gunn, M. D.; Fecci, P. E.
10.1101/2023.02.02.526713 — immunology — Posted on 2023-02-03
3649 EMBER multi-dimensional spectral microscopy enables quantitative determination of disease- and cell-specific amyloid strains
Yang, H.; Yuan, P.; Wu, y.; Shi, M.; caro, C.; tengeiji, a.; yamanoi, s.; Inoue, M.; DeGrado, W.; Condello, C.
10.1101/2023.02.01.526692 — neuroscience — Posted on 2023-02-03
3652 Nociceptor neuroimmune interactomes reveal cell type- and injury-specific inflammatory pain pathways
Jain, A.; Gyori, B.; Hakim, S.; Bunga, S.; Taub, D. G.; Ruiz-Cantero, M. C.; Tong-Li, C.; Andrews, N.; Sorger, P. K.; Woolf, C. J.
10.1101/2023.02.01.526526 — neuroscience — Posted on 2023-02-03
3653 Identical tau filaments in subacute sclerosing panencephalitis and chronic traumatic encephalopathy
Qi, C.; Hasegawa, M.; Takao, M.; Sakai, M.; Sasaki, M.; Mizutani, M.; Akagi, A.; Iwasaki, Y.; Miyahara, H.; Yoshida, M.; Scheres, S.; Goedert, M.
10.1101/2023.02.02.526771 — neuroscience — Posted on 2023-02-03
3655 Oral administration of 4-methylumbelliferone reduces glial scar and promotes anatomical plasticity
Stepankova, K.; Chudickova, M.; Simkova, Z.; Martinez-Varea, N.; Kubinova, S.; Urdzikova, L.; Jendelova, P.; Kwok, J. C. F.
10.1101/2023.02.02.526565 — neuroscience — Posted on 2023-02-03
3660 HIV viral protein R induces loss of DCT1-type renal tubules
Latt, K. Z.; Yoshida, T.; Shrivastav, S.; Abedini, A.; Reece, J. M.; Lee, H.; Okamoto, K.; Heymann, J.; Zhao, Y.; Chung, J.-Y.; Hewitt, S.; Jose, P. A.; Winkler, C. A.; Knepper, M. A.; Kino, T.; Rosenberg, A. Z.; Susztak, K.; Kopp, J. B.
10.1101/2023.02.02.526686 — pathology — Posted on 2023-02-03
3661 SCCA1/SERPINB3 promotes suppressive immune environment via STAT-dependent chemokine production, blunting the therapy-induced T cell responses
Markovina, S.; Chen, L.-Y.; Shi, V.; Wang, S.; Freeman, R.; Ruiz, F.; Jayachandran, K.; Zhang, J.; Cosper, P.; Sun, L.; Luke, C.; Spina, C.; Grigsby, P.; Schwarz, J.
10.1101/2023.02.01.526675 — cancer biology — Posted on 2023-02-03
3662 Robust biomarker discovery through multiplatform multiplex image analysis of breast cancer clinical cohorts
Eng, J. R.; Bucher, E.; Hu, Z.; Sanders, M.; Chakravarthy, B.; Pietenpol, J. A.; Gibbs, S. L.; Chin, K.
10.1101/2023.01.31.525753 — cancer biology — Posted on 2023-02-03
3663 Irreversible inhibition of TRF2TRFH recruiting functions: a strategy to induce telomeric replication stress in cancer cells.
Sobinoff, A. P.; Di Maro, S.; Low, R. R. J.; Benedetti, R.; Tomassi, S.; D'Aniello, A.; Russo, R.; Baglivo, I.; Chianese, U.; Pedone, P. V.; Chambery, A.; Cesare, A. J.; Altucci, L.; Pickett, H. A.; Cosconati, S.
10.1101/2023.02.01.526591 — cancer biology — Posted on 2023-02-03
3668 Thermal Stimulus Task fMRI in the Cervical Spinal Cord at 7 Tesla
Seifert, A. C.; Xu, J.; Kong, Y.; Eippert, F. C.; Miller, K. L.; Tracey, I.; Vannesjo, S. J.
10.1101/2023.01.31.526451 — bioengineering — Posted on 2023-02-03
3672 Alpha-synuclein pre-formed fibrils injected into prefrontal cortex primarily impact cortical and subcortical structures and lead to restricted behavioral impacts
Weber, M. A.; de Choisy, G.; Thangavel, R.; Conlon, M. M.; Abdelmotilib, H. A.; Halhouli, O.; Zhang, Q.; Geerling, J. C.; Narayanan, N. S.; Aldridge, G. M.
10.1101/2023.01.31.526365 — animal behavior and cognition — Posted on 2023-02-03
3674 Discovery of NRG1-VII: a novel myeloid-derived class of NRG1 isoforms
Angel Berrocal-Rubio, M.; Prawer, Y. D. J.; Dinevska, M.; De Paoli-Iseppi, R.; Widodo, S. S.; Rajab, N.; De Nardo, W.; Hallab, J. C.; Li, A.; Mantamadiotis, T.; Clark, M.; Wells, C.
10.1101/2023.02.02.525781 — genomics — Posted on 2023-02-03
3675 A multiomics approach to understanding pathology of Combined D,L-2- Hydroxyglutaric Aciduria and phenylbutyrate as potential treatment
Phua, Y. L.; D'Annibale, O. M.; Karunanidhi, A.; Mohsen, A.-W.; Kirmse, B.; Dobrowolski, S. F.; Vockley, J.
10.1101/2023.02.02.526527 — genetics — Posted on 2023-02-03
3681 B cell repertoire in children with skin barrier dysfunction supports altered IgE maturation associated with allergic food sensitization
Gill, K.; Moore, C.; Nwogu, O.; Kroner, J. W.; Chang, W.-C.; Stevens, M. L.; Baatyrbek kyzy, A.; Biagini, J.; Devonshire, A.; Kottyan, L.; Schwartz, J.; Assa'ad, A.; Martin, L.; Andorf, S.; Hershey, G. K.; Roskin, K. M.
10.1101/2023.02.01.526538 — immunology — Posted on 2023-02-03
3685 Deficient mitochondrial respiration impairs sirtuin activity in dorsal root ganglia in Friedreich Ataxia mouse and cell models
Sanz-Alcazar, A.; Britti, E.; Delaspre, F.; Medina-Carbonero, M.; Pazos-Gil, M.; Tamarit, J.; ROS, J.; Cabiscol, E.
10.1101/2023.02.01.526688 — neuroscience — Posted on 2023-02-03
3687 An electrochemical approach for rapid, sensitive, and selective detection of dynorphin
Conway, S. M.; Kuo, C.-C.; Gardiner, W.; Wu, R.-N.; Thang, L.; Gereau, G.; Yuede, C.; Cirrito, J.; McCall, J. G.; Al-Hasani, R.
10.1101/2023.02.01.526701 — neuroscience — Posted on 2023-02-03
3689 Path integration selectively predicts midlife risk of Alzheimer's disease
Newton, C.; Pope, M.; Rua, C.; Henson, R.; Ji, Z.; Burgess, N.; Rodgers, C. T.; Stangl, M.; Dounavi, M.-E.; Castegnaro, A.; Koychev, I.; Malhotra, P.; Wolbers, T.; Ritchie, K.; Ritchie, C.; O'Brien, J.; Su, L.; Chan, D.
10.1101/2023.01.31.526473 — neuroscience — Posted on 2023-02-03
3691 Large-scale brain-wide neural recording in nonhuman primates
Trautmann, E. M.; Hesse, J. K.; Stine, G.; Xia, R.; Shude Zhu, S.; O'Shea, D. J.; Karsh, B.; Colonell, J.; Lanfranchi, F.; Vyas, S.; Zimnik, A.; Steinemann, N. A.; Wagenaar, D. A.; Andrei, A.; Mora Lopez, C.; OCallaghan, J. M.; Putzeys, J.; Raducanu, B. C.; Welkenhuysen, M.; Churchland, M.; Moore, T.; Shadlen, M. N.; Shenoy, K. V.; Tsao, D.; Dutta, B.; Harris, T.
10.1101/2023.02.01.526664 — neuroscience — Posted on 2023-02-03
3693 Neuromuscular Basis of Drosophila larval escape behavior
Cooney, P. C.; Li, W.; Huang, Y.; Hormigo, R.; Tabachnik, T.; Hillman, E. M. C.; Grueber, W. B.; Zarin, A. A.
10.1101/2023.02.01.526733 — neuroscience — Posted on 2023-02-03
3697 ENVIRONMENT MODULATES PROTEIN HETEROGENEITY THROUGH TRANSCRIPTIONAL AND TRANSLATIONAL STOP CODON MISCODING
Romero-Romero, M. L.; Kirilenko, A.; Poehls, J.; Richter, D.; Jumel, T.; Shevchenko, A.; Toth-Petroczy, A.
10.1101/2023.02.01.526636 — systems biology — Posted on 2023-02-03
3698 The unknown lipids project: harmonized methods improve compound identification and data reproducibility in an inter-laboratory untargeted lipidomics study
Shen, T.; Conway, C.; Rempfert, K. R.; Kyle, J. E.; Colby, S. M.; Gaul, D. A.; Habra, H.; Kong, F.; Bloodsworth, K. J.; Allen, D.; Evans, B.; Du, X.; Fernandez, F.; Metz, T. O.; Fiehn, O.; Evans, C. R.
10.1101/2023.02.01.526566 — systems biology — Posted on 2023-02-03
3699 Climate, caribou and human needs linked by analysis of Indigenous and scientific knowledge
Gagnon, C. A.; Hamel, S.; Russell, D. E.; Andre, J.; Buckle, A.; Haogak, D.; Pascal, J.; Schafer, E.; Powell, T.; Svoboda, M. Y.; Berteaux, D.
10.1101/2023.02.01.526335 — systems biology — Posted on 2023-02-03
3701 EntomonVR: a New Virtual Reality Game for Learning Insect Morphology
Pasandideh Saqalaksari, M.; Talebi, A. A.; van de Kamp, T.; Reyhani Haghighi, S.; Zimmermann, D.; Richter, A.
10.1101/2023.02.01.526587 — scientific communication and education — Posted on 2023-02-03
3702 Killing them softly with EPO: a new role for erythropoietin in the homeostasis of red blood cells
Fernandez Arias, C.; Valente-Leal, N.; Bertocchini, F.; Marques, S.; Acosta, F. J.; Fernandez-Arias, C.
10.1101/2023.01.31.526417 — physiology — Posted on 2023-02-03
3703 FHF2 phosphorylation and regulation of native myocardial NaV1.5 channels
Lesage, A.; Lorenzini, M.; Burel, S.; Sarlandie, M.; Bibault, F.; Maloney, D.; Silva, J.; Townsend, R. R.; Nerbonne, J. M.; Marionneau, C.
10.1101/2023.01.31.526475 — physiology — Posted on 2023-02-03
3704 Linking Muscle Mechanics to the Metabolic Cost of Human Hopping
Jessup, L. N.; Kelly, L. A.; Cresswell, A. G.; Lichtwark, G. A.
10.1101/2023.01.31.526545 — physiology — Posted on 2023-02-03
3706 Elamipretide Improves ADP Sensitivity in Aged Mitochondria by Increasing Uptake through the Adenine Nucleotide Translocator (ANT)
Pharaoh, G.; Kamat, V.; Kannan, S.; Stuppard, R. S.; Whitson, J.; Martin-Perez, M.; Qian, W.-J.; MacCoss, M. J.; Villen, J.; Rabinovitch, P.; Campbell, M. D.; Sweet, I. R.; Marcinek, D. J.
10.1101/2023.02.01.525989 — physiology — Posted on 2023-02-03
3707 Optimizing anesthesia and delivery approaches for dosing into lungs of mice
Seo, Y.; Qiu, L.; Magnen, M.; Conrad, C.; Moussavi-Harami, S. F.; Looney, M. R.; Cleary, S. J.
10.1101/2023.02.01.526706 — physiology — Posted on 2023-02-03
3710 Three-dimensional spatial quantitative analysis of cardiac lymphatics in the mouse heart
Phillips, E. H.; Bindokas, V. P.; Jung, D.; Teamer, J.; Kitajewski, J. K.; Solaro, R. J.; Wolska, B. M.; Lee, S. S.-Y.
10.1101/2023.02.01.526338 — pathology — Posted on 2023-02-03
3712 B3GALT6 Promotes Dormant Breast Cancer Cell Survival and Recurrence by Enabling Heparan Sulfate-Mediated FGF Signaling
Sreekumar, A.; Lu, M.; Choudhury, B.; Pan, T.-c.; Pant, D. K.; Sterner, C. J.; Belka, G. K.; Toriumi, T.; Benz, B.; Escobar-Aguirre, M.; Marino, F. E.; Esko, J. D.; Chodosh, L. A.
10.1101/2023.01.31.526529 — cancer biology — Posted on 2023-02-03
3713 LCP1 Regulates Cell Motility in Chondrosarcoma and Correlates with Metastatic Potential and Poor Patient Outcomes
Watson, C. A.; Martin, J. T.; Nakagawa, M.; Guardino, N.; Zou, T.; Peairs, E.; Krez, A.; Nadesan, P.; Huang, Z.; Ou, J.; Somarelli, J.; Alman, B.; Visgauss, J. D.
10.1101/2023.01.31.526513 — cancer biology — Posted on 2023-02-03
3714 The gene expression classifier ALLCatchR identifies B-precursor ALL subtypes and underlying developmental trajectories across age
Beder, T.; Hansen, B.-T.; Hartmann, A. M.; Zimmermann, J.; Amelunxen, E.; Wolgast, N.; Walter, W.; Zaliova, M.; Antic, Z.; Chouvarine, P.; Bartsch, L.; Barz, M.; Bultmann, M.; Horns, J.; Bendig, S.; Kaessens, J.; Kaleta, C.; Cario, G.; Schrappe, M.; Neumann, M.; Goekbuget, N.; Bergmann, A. K.; Trka, J.; Haferlach, C.; Brueggemann, M.; Baldus, C. D.; Bastian, L.
10.1101/2023.02.01.526553 — cancer biology — Posted on 2023-02-03
3715 Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination
Wang, Y.-C.; Kelso, A. A.; Karamafrooz, A.; Chen, Y.-H.; Chen, W.-K.; Cheng, C.-T.; Qi, Y.; Gu, L.; Malkas, L.; Kung, H.-J.; Moldovan, G.-L.; Ciccia, A.; Stark, J. M.; Ann, D. K.
10.1101/2023.01.31.526362 — cancer biology — Posted on 2023-02-03
3721 dGAE(297-391) tau fragment promotes formation of CTE-like full-length tau filaments
Kitoka, K.; Lends, A.; Kucinskas, G.; Bula, A. L.; Krasauskas, L.; Smirnovas, V.; Skrabana, R.; Hritz, J.; Jaudzems, K.
10.1101/2023.02.01.526268 — biophysics — Posted on 2023-02-03
3723 Proteome encoded determinants of protein sorting into extracellular vesicles
Waury, K.; Gogishvili, D.; Nieuwland, R.; Chatterjee, M.; Teunissen, C. E.; Abeln, S.
10.1101/2023.02.01.526570 — bioinformatics — Posted on 2023-02-03
3727 Construction of a searchable database for gene expression changes in spinal cord injury experiments
Rouchka, E. C.; de Almeida, C.; House, R. B.; Daneshmand, J. C.; Chariker, J. H.; Saraswat Ohri, S.; Gomes, C.; Sharp, M.; Shum-Siu, A.; Cesarz, G. M.; Petruska, J. C.; Magnuson, D. S. K.
10.1101/2023.02.01.526630 — bioinformatics — Posted on 2023-02-03
3731 Gold Nanoparticles for Monitoring of Mesenchymal Stem Cell-Loaded Bioresorbable Polymeric Wraps for Arteriovenous Fistulas
Barcena, A. J. R.; Perez, J. V. D.; Damasco, J. A.; Bernardino, M. R.; San Valentin, E. M. D.; Klusman, C.; Martin, B.; Cortes, A.; Canlas, G.; Del Mundo, H. C.; Heralde, F. M.; Avritscher, R.; Fowlkes, N.; Bouchard, R. R.; Cheng, J.; Huang, S. Y.; Melancon, M. P.
10.1101/2023.02.01.526611 — bioengineering — Posted on 2023-02-03
3732 Light sheet autofluorescence lifetime imaging with a single photon avalanche diode array
Samimi, K.; Desa, D. E.; Lin, W.; Weiss, K.; Li, J.; Huisken, J.; Miskolci, V.; Huttenlocher, A.; Chacko, J. V.; Velten, A.; Rogers, J. D.; Eliceiri, K. W.; Skala, M. C.
10.1101/2023.02.01.526695 — bioengineering — Posted on 2023-02-03
3738 A chemoproteomic platform for reactive fragment profiling against the deubiquitinases
Cookson, R.; Vuorinen, A.; Pettinger, J.; Kennedy, C. R.; Kirkpatrick, J. M.; Peltier-Heap, R. E.; Powell, A.; Snijders, A. P.; Skehel, M.; House, D.; Rittinger, K.; Bush, J. T.
10.1101/2023.02.01.526632 — biochemistry — Posted on 2023-02-03
3742 Structure of the ceramide-bound SPOTS complex
Schafer, J.-H.; Korner, C.; Esch, B. M.; Limar, S.; Parey, K.; Walter, S.; Januliene, D.; Moeller, A.; Frohlich, F.
10.1101/2023.02.03.526835 — biochemistry — Posted on 2023-02-03
3747 Hypothesis-free phenotype prediction within a genetics-first framework
Lu, C.; Zaucha, J.; Gam, R.; Fang, H.; Smithers, B.; Oates, M. E.; Bernabe-Rubio, M.; Williams, J.; Zelenka, N.; Pandurangan, A.; Tandon, H.; Shihab, H.; Kalaivani, R.; Sung, M.; Sardar, A.; Greshake Tzovaras, B.; Danovi, D.; Gough, J.
10.1101/2023.02.01.526358 — genomics — Posted on 2023-02-03
3748 Detection and Phylogenetic Analysis of Highly Pathogenic A/H5N1 Avian Influenza Clade 2.3.4.4b Virus in Chile, 2022
Jimenez-Bluhm, P.; Siegers, J. Y.; Tan, S.; Sharp, B.; Freiden, P.; Johow, M.; Orozco, K.; Ruiz, S.; Baumberger, C.; Galdames, P.; Gonzalez, M. A.; Rojas, C.; Karlsson, E. A.; Hamilton-West, C. N.; Schultz-Cherry, S.
10.1101/2023.02.01.526205 — genetics — Posted on 2023-02-03
3749 Unraveling the causal genes and transcriptomic determinants of human telomere length
Cao, J.; Shen, Y.; Fan, X.; Yang, H.; Dong, X.; Zhang, S.; Yi, X.; Shuai, L.; Shi, L.; Liu, Z.; Yang, J.; Hao, J.; Chen, K.; Huang, D.; Wang, F.; Li, M. J.
10.1101/2023.02.01.526642 — genetics — Posted on 2023-02-03
3751 Short structural variation fuelled CAM evolution within an explosive bromeliad radiation
Groot Crego, C.; Hess, J.; Yardeni, G.; de la Harpe, M.; Beclin, F.; Cauz-Santos, L. A.; Saadain, S.; Barbara, T.; Temsch, E. M.; Weiss-Schneeweiss, H.; Barfuss, M. H. J.; Till, W.; Heyduk, K.; Lexer, C.; Paun, O.; Leroy, T.
10.1101/2023.02.01.526631 — evolutionary biology — Posted on 2023-02-03
3757 A Chromosome-Level Genome Assembly for the Rock Ptarmigan (Lagopus muta)
Rodin Morch, P. E.; Squires, T. E.; Formenti, G.; Tracey, A.; Abueg, L. A.; Brajuka, N.; Jarvis, E. D.; Melsted, P.; Höglund, J.; Magnusson, K. P.
10.1101/2023.01.31.526508 — molecular biology — Posted on 2023-02-03
3759 Streamlined and sensitive mono- and diribosome profiling in yeast and human cells
Ferguson, L.; Upton, H. E.; Pimentel, S. C.; Mok, A.; Lareau, L. F.; Collins, K.; Ingolia, N. T.
10.1101/2023.02.01.526718 — molecular biology — Posted on 2023-02-03
3760 Virus-host dynamics in archaeal groundwater biofilms and the associated bacterial community composition
Turzynski, V.; Griesdorn, L.; Moraru, C.; Soares, A.; Simon, S. A.; Stach, T. L.; Rahlff, J.; Esser, S. P.; Probst, A. J.
10.1101/2023.02.03.526798 — microbiology — Posted on 2023-02-03
3761 Novel diversity of polar Cyanobacteria revealed by genome-resolved metagenomics
Pessi, I. S.; Popin, R. V.; Durieu, B.; Lara, Y.; Savaglia, V.; Roncero-Ramos, B.; Hultman, J.; Verleyen, E.; Vyverman, W.; Wilmotte, A.
10.1101/2023.02.03.526606 — microbiology — Posted on 2023-02-03
3763 Transcriptional survey of ovarian bacteriomes in the cereal weevil, Sitophilus oryzae, shows down-regulation of immune effectors at the onset of sexual maturity
Ferrarini, M. G.; Vallier, A.; Dell'Aglio, E.; Balmand, S.; Vincent-Monegat, C.; Debbache, M.; Maire, J.; Parisot, N.; Zaidman-Remy, A.; Heddi, A.; Rebollo, R.
10.1101/2023.01.31.526389 — immunology — Posted on 2023-02-03
3764 Stroke induces early recurrent vascular events by inflammasome-dependent atherosclerotic plaque rupture
Cao, J.; Roth, S.; Zhang, S.; Kopczak, A.; Georgakis, M. K.; Li, X.; Dutsch, A.; Liman, T. G.; Endres, M.; Brough, D.; Green, J. P.; Wernsdorf, S. R.; Fürle, C.; Carofiglio, O.; Zhu, J.; Asare, Y.; DEMDAS Study Group, ; Dichgans, M. K.; Sager, H. B.; Grosse, G. M.; Liesz, A.
10.1101/2023.02.01.526550 — immunology — Posted on 2023-02-03
3765 A thin-film optogenetic visual prosthesis
Knudsen, E. B.; Zappitelli, K.; Brown, J.; Reeder, J.; Smith, K. S.; Rostov, M.; Choi, J.; Rochford, A.; Slager, N.; Miura, S. K.; Rodgers, K.; Reed, A.; Lewis Israeli, Y. R.; Shiraga, S.; Seo, K. J.; Wolin, C.; Dawson, P.; Eltaeb, M.; Dasgupta, A.; Chong, P.; Charles, S.; Stewart, J. M.; Silva, R. A.; Kim, T.; Kong, Y.; Mardinly, A. R.; Hodak, M.
10.1101/2023.01.31.526482 — neuroscience — Posted on 2023-02-03
3767 A cortical mechanism linking saliency detection and motor reactivity in rhesus monkeys
Novembre, G.; Lacal, I.; Benusiglio, D.; Quarta, E.; Schito, A.; Grasso, S.; Caratelli, L.; Caminiti, R.; Battaglia Mayer, A.; Iannetti, G.
10.1101/2023.01.31.526437 — neuroscience — Posted on 2023-02-03
3768 Aberrant circuitry underlying olfaction in the face of severe olfactory bulb degeneration
Licht, T.; Yunerman, M.; Maor, I.; Lawabny, N.; Oz Rokach, R.; Mizrahi, A.; Rokni, D.
10.1101/2023.01.31.526422 — neuroscience — Posted on 2023-02-03
3770 DeepD3, an Open Framework for Automated Quantification of Dendritic Spines
Fernholz, M. H. P.; Guggiana Nilo, D. A.; Bonhoeffer, T.; Kist, A. M.
10.1101/2023.02.01.526476 — neuroscience — Posted on 2023-02-03
3775 RGS14 is neuroprotective against seizure-induced mitochondrial oxidative stress and pathology in hippocampus
Harbin, N. H.; Lustberg, D. J.; Hurst, C.; Pare, J.-F.; Crotty, K. M.; Waters, A. L.; Yeligar, S. M.; Smith, Y.; Seyfried, N. T.; Weinshenker, D.; Hepler, J. R.
10.1101/2023.02.01.526349 — neuroscience — Posted on 2023-02-03
3777 Cell-free multi-omics analysis reveals tumor status-informative signatures in gastrointestinal cancer patients' plasma
Tao, Y.; Xing, S.; Zuo, S.; Bao, P.; Jin, Y.; Li, Y.; Wu, Y.; Chen, S.; Wang, X.; Zhu, Y.; Feng, Y.; Zhang, X.; Wang, X.; Xi, Q.; Lu, Q.; Wang, P.; Lu, Z. J.
10.1101/2023.01.31.526431 — systems biology — Posted on 2023-02-03
3779 Engineering a symbiont as a biosensor for the honey bee gut environment
Chhun, A.; Zoppi, F.; Moriano-Gutierrez, S.; Cabirol, A.; Engel, P.; Schaerli, Y.
10.1101/2023.02.02.526826 — synthetic biology — Posted on 2023-02-03
3781 Barking up the wrong tree: the importance of morphology in plant molecular phylogenetic studies
de Almeida, R. F.; Cheek, M.; Pellegrini, M.; de Morais, I. L.; Simao-Bianchini, R.; Rattanakrajang, P.; Simoes, A. R.
10.1101/2023.01.30.526223 — plant biology — Posted on 2023-02-03
3782 Danicamtiv increases myosin recruitment and alters the chemomechanical cross bridge cycle in cardiac muscle
Kooiker, K. B.; Mohran, S.; Turner, K. L.; Ma, W.; Flint, G.; Qi, L.; Gao, C.; Zheng, Y.; McMillen, T. S.; Mandrycky, C.; Martinson, A.; Mahoney-Schaefer, M.; Freeman, J. C.; Costales Arenas, E. G.; Tu, A.-Y.; Irving, T. C.; Geeves, M. A.; Tanner, B. C. W.; Regnier, M.; Davis, J.; Moussavi-Harami, F.
10.1101/2023.01.31.526380 — physiology — Posted on 2023-02-03
3784 Interpretation of body condition index should be informed by natural history
Wishart, A. E.; Guerrero-Chacon, A. L.; Smith, R.; Hawkshaw, D. M.; McAdam, A. G.; Dantzer, B.; Boutin, S.; Lane, J.
10.1101/2023.01.31.524791 — physiology — Posted on 2023-02-03
3785 Metabolic impact of trans 10, cis 12-conjugated linoleic acid in pai transgenic mice
Rao, Y.; Li, S. L.; Li, M. J.; Wang, B. Z.; Wang, Y. Y.; Liang, L. W.; Yu, S.; Liu, Z. P.; Cui, S.; GOU, K. M.
10.1101/2023.01.31.526123 — physiology — Posted on 2023-02-03
3788 Epigenetic Regulation Explains The Functionality Behind Colon Cancer Specific Biomarker Septin9
Vizkeleti, L.; Kiss, C.; Tisza, V.; Szigeti, A.; Gellert, A.; Csabai, I.; Pongor, L. S.; Spisak, S.
10.1101/2023.01.31.526413 — cancer biology — Posted on 2023-02-03
3789 Deep-Learning Assisted, Single-molecule Imaging analysis (Deep-LASI) of multi-color DNA Origami structures
Wanninger, S.; Asadiatouei, P.; Bohlen, J.; Salem, C.-B.; Tinnefeld, P.; Ploetz, E.; Lamb, D. C.
10.1101/2023.01.31.526220 — biophysics — Posted on 2023-02-03
3790 Liquid spherical shells are a non-equilibrium steady state
Bergmann, A. M.; Bauermann, J.; Bartolucci, G.; Donau, C.; Stasi, M.; Holtmannspoetter, A.-L.; Julicher, F.; Weber, C. A.; Boekhoven, J.
10.1101/2023.01.31.526480 — biophysics — Posted on 2023-02-03
3791 Theoretical model of membrane protrusions driven by curved active proteins
Ravid, Y.; Penic, S.; Mimori-Kiyosue, Y.; Suetsugu, S.; Iglic, A.; Gov, N.
10.1101/2023.01.31.526240 — biophysics — Posted on 2023-02-03
3793 Analysis of AlphaFold and molecular dynamics structure predictions of mutations in serpins
Garrido-Rodriguez, P.; Carmena-Bargueno, M.; de la Morena-Barrio, M. E.; Bravo-Perez, C.; de la Morena-Barrio, B.; Cifuentes-Riquelme, R.; Lozano, M. L.; Perez Sanchez, H.; Corral, J.
10.1101/2023.01.31.526415 — bioinformatics — Posted on 2023-02-03
3797 Serial Capture Affinity Purification and Integrated Structural Modeling of the H3K4me3 Binding and DNA Damage Related WDR76:SPIN1 Complex
Liu, X.; Zhang, Y.; Wen, Z.; Hao, Y.; Banks, C.; Lange, J. J.; Cesare, J.; Bhattacharya, S.; Slaughter, B.; Unruh, J.; Florens, L.; Workman, J.; Washburn, M.
10.1101/2023.01.31.526478 — biochemistry — Posted on 2023-02-03
3798 BARD1 germline variants induce haploinsufficiency and DNA repair defects in neuroblastoma
Randall, M. P.; Egolf, L. E.; Vaksman, Z.; Samanta, M.; Tsang, M.; Groff, D.; Evans, J. P.; Rokita, J. L.; Layeghifard, M.; Shlien, A.; Maris, J.; Diskin, S. J.; Bosse, K. R.
10.1101/2023.01.31.525066 — genetics — Posted on 2023-02-03
3799 ClockstaRX: testing molecular clock hypotheses with genomic data
Duchene, D. A.; Duchene, S.; Stiller, J.; Heller, R.; Ho, S. Y. W.
10.1101/2023.02.02.526226 — molecular biology — Posted on 2023-02-03
3800 TLN468 changes the pattern of tRNA used to readthrough premature termination codons in CFTR
Karri, S.; Bidou, L.; Cornu, D.; biri, L.; Hinzpeter, A.; Serot, C.; Sermet-Gaudelus, I.; NAMY, O.
10.1101/2023.02.02.526440 — molecular biology — Posted on 2023-02-03
3803 Sterile triggers drive joint inflammation in TNF and IL-1beta dependent mouse arthritis models
Thiran, A.; Petta, I.; Blancke, G.; Thorp, M.; Plankaert, G.; Jans, M.; Andries, V.; Barbry, K.; Hochepied, T.; Vanhove, C.; Gracey, E.; Dumas, E.; Manuelo, T.; Josipovic, I.; van Loo, G.; Elewaut, D.; Vereecke, L.
10.1101/2023.01.31.526410 — immunology — Posted on 2023-02-03
3805 Simulation-based inference for efficient identification of generative models in connectomics
Boelts, J.; Harth, P.; Gao, R.; Udvary, D.; Yanez, F.; Baum, D.; Hege, H.-C.; Oberlaender, M.; Macke, J. H.
10.1101/2023.01.31.526269 — neuroscience — Posted on 2023-02-03
3807 DeltaF508-Cftr mutation in genetically diverse Collaborative Cross mice yields novel disease-relevant phenotypes for cystic fibrosis
Sipione, B.; Lore, N. I.; Sanvito, F.; Rossi, G.; Neri, A.; Gianferro, F.; Tascini, S. A.; Livraghi-Butrico, A.; Cigana, C.; Bragonzi, A.
10.1101/2023.01.31.526098 — pathology — Posted on 2023-02-03
3808 Capturing the mechanosensitivity of cell proliferation in models of epithelium
Hollring, K.; Nuic, L.; Rogic, L.; Kaliman, S.; Gehrer, S.; Rehfeldt, F.; Hubert, M.; Smith, A.-S.
10.1101/2023.01.31.526438 — biophysics — Posted on 2023-02-03
3814 Mechanisms of SARS-CoV-2 Inactivation using UVC Laser Radiation
Devitt, G.; Johnson, P. B.; Hanrahan, N.; Lane, S. I. R.; Vidale, M. C.; Sheth, B.; Allen, J. D.; Humbert, M. V.; Spalluto, C. M.; Herve, R. C.; Staples, K.; West, J.; Forster, R.; Divecha, N.; McCormick, C. J.; Crispin, M.; Hempler, N.; Malcolm, G. P. A.; Mahajan, S.
10.1101/2023.02.03.526944 — microbiology — Posted on 2023-02-03
3815 IMPACT: a web server for exploring immunotherapeutic predictive and cancer prognostic biomarkers
Liu, Y.; Zhang, Y.; Xie, W.; Zhao, J.; Dong, Y.; Xu, C.; Wang, Y.; Li, M.; Wang, G.; Zhu, X.; Wang, W.; Lin, K.; Lu, H.; Han, Y.; Li, L.; Duan, J.; Cai, S.; Wang, J.; Wang, Z.
10.1101/2023.01.31.526401 — bioinformatics — Posted on 2023-02-03
3819 Uncertainty in crop phenology simulations is driven primarily by parameter variability
Wallach, D.; Palosuo, T.; Mielenz, H.; Buis, S.; Thorburn, P.; Asseng, S.; Dumont, B.; Ferrise, R.; Gayler, S.; Ghahramani, A.; Harrison, M. T.; Hochman, Z.; Hoogenboom, G.; Huang, M.; Jing, Q.; Justes, E.; Kersebaum, K. C.; Launay, M.; Lewan, E.; Liu, K.; Luo, Q.; Mequanint, F.; Nendel, C.; Padovan, G.; Olesen, J. E.; Pullens, J. W. M.; Qian, B.; Seserman, D.-M.; Shelia, V.; Souissi, A.; Specka, X.; Wang, J.; Weber, T. K. D.; Weihermuller, L.; Seidel, S.
10.1101/2023.02.03.526931 — plant biology — Posted on 2023-02-03
3820 Multi-species polyploidization, chromosome shuffling, and genome extraction in Zea/Tripsacum hybrids
Iqbal, M. Z.; Wen, X.; Lulu, X.; Zhao, Y.; Jing, L.; Weiming, J.; Mingjun, C.; Li, H.; Li, Y.; Xiaofeng, L.; He, R.; He, J.; Yan, P.; Rong, T.; Tang, Q.
10.1101/2023.02.02.526764 — genetics — Posted on 2023-02-03
3822 Identifying and tracking mobile elements in evolving compost communities yields insights into the nanobiome
Dijk, B. v.; Farr, A.; Buffard, P.; Giersdorf, F.; Meijer, J.; Dutilh, B. E.; Rainey, P. B.
10.1101/2023.02.02.526783 — microbiology — Posted on 2023-02-03
3823 Glutaredoxin regulation of primary root growth confers early drought stress tolerance in pearl millet
de la Fuente Canto, C.; Grondin, A.; Sine, B.; Debieu, M.; Belin, C.; Hajjarpoor, A.; Atkinson, J.; Passot, S.; Salson, M.; Orjuela, J.; Tranchant, C.; Brossier, J.-R.; Steffen, M.; Morgado, C.; Dinh, H. N.; Pandey, B. K.; Darmau, J.; Champion, A.; Petitot, A.-S.; Barrachina, C.; Pratlong, M.; Mounier, T.; Gantet, P.; Gangashetty, P.; Guedon, Y.; Vadez, V.; Reichheld, J.-P.; Bennett, M. J.; Kane, N. A.; Guyomarc'h, S.; Wells, D. M.; Vigouroux, Y.; Laplaze, L.
10.1101/2023.02.02.526762 — plant biology — Posted on 2023-02-03
3828 Subcellular second messenger networks drive distinct repellent-induced axon behaviors
Baudet, S.; Zagar, Y.; Roche, F.; Gomez-Bravo, C.; Couvet, S.; Becret, J.; Belle, M.; Ros, O.; Nicol, X.
10.1101/2023.02.02.526245 — developmental biology — Posted on 2023-02-03
3830 Lifelong tissue memory relies on spatially organised dedicated progenitors located distally from the injury
Levron, C. L.; Watanabe, M.; Proserpio, V.; Piacenti, G.; Lauria, A.; Kaltenbach, S.; Nohara, T.; Anselmi, F.; Duval, C.; Donna, D.; Baev, D.; Natsuga, K.; Hagai, T.; Oliviero, S.; Donati, G.
10.1101/2023.02.02.526841 — cell biology — Posted on 2023-02-03
3831 Calcium transients trigger switch-like discharge of prostaglandin E2 (PGE2) in an ERK-dependent manner
Watabe, T.; Yamahira, S.; Takakura, K.; Thumkeo, D.; Narumiya, S.; Matsuda, M.; Terai, K.
10.1101/2023.02.01.526734 — cell biology — Posted on 2023-02-03
3842 Cryo-electron tomography of C. elegans mitochondria reveals how the ATP synthase dimer interface shapes crista membranes
Buzzard, E.; McLaren, M.; Bragoszewski, P.; Brancaccio, A.; Ford, H.; Daum, B.; Kuwabara, P.; Collinson, I.; Gold, V.
10.1101/2023.02.02.526626 — biochemistry — Posted on 2023-02-03
3843 Modelling the Erythroblastic Island Niche of Dyserythropoietic Anaemia Type IV patients using Induced Pluripotent Stem Cells
May, A.; Ventura, T.; Fidanza, A.; Volmer, H.; Taylor, H. A.; Romano, N.; D'Souza, S. L.; Bieker, J. J.; Forrester, L. M.
10.1101/2023.02.02.526657 — cell biology — Posted on 2023-02-03
3844 ADO-MEDIATED SYNTHESIS OF TAURINE ALTERS THE CHROMATIN LANDSCAPE OF INGUINAL ADIPOSE TISSUE TO ENHANCE NON-SHIVERING THERMOGENESIS
Tsai, P.-Y.; Shui, B.; Lee, S.; Liu, Y.; Qu, Y.; Cheng, C.; Edwards, K.; Wong, C.; Meng-Killeen, R.; Soloway, P.; Barrow, J. J.
10.1101/2023.02.02.526843 — cell biology — Posted on 2023-02-03
3846 A harmonized public resource of deeply sequenced diverse human genomes
Koenig, Z.; Yohannes, M. T.; Nkambule, L. L.; Goodrich, J. K.; Kim, H. A.; Zhao, X.; Wilson, M. W.; Tiao, G.; Hao, S. P.; Sahakian, N.; Chao, K. R.; gnomAD Project Consortium, ; Talkowski, M. E.; Daly, M. J.; Brand, H.; Karczewski, K.; Atkinson, E. G.; Martin, A.
10.1101/2023.01.23.525248 — genomics — Posted on 2023-02-02
3849 Noradrenaline release from the locus coeruleus shapes stress-induced hippocampal gene expression
Privitera, M.; von Ziegler, L. M.; Floriou-Servou, A.; Duss, S. N.; Zhang, R.; Leimbacher, S.; Sturman, O.; Waag, R.; Roessler, F.; Heylen, A.; Vermeiren, Y.; Van Dam, D.; De Deyn, P. P.; Bohacek, J.
10.1101/2023.02.02.526661 — neuroscience — Posted on 2023-02-02
3850 Grey matter reshaping of language-related regions depends on tumor lateralization
Manso-Ortega, L.; de Frutos-Sagastuy, L.; Gisbert-Munoz, S.; Salamon, N.; Qiao, J.; Walshaw, P.; Quinones, I.; M. Polczynska, M.
10.1101/2023.02.02.526219 — neuroscience — Posted on 2023-02-02
3851 Functional Connectivity of the Cerebellar Vermis in Bipolar Disorder and Associations with Mood
Saleem, A.; Harmata, G.; Jain, S.; Voss, M. W.; Fiedorowicz, J. G.; Williams, A. J.; Shaffer, J. J.; Richards, J. G.; Barsotti, E. J.; Sathyaputri, L.; Schmitz, S. L.; Christensen, G. E.; Long, J. D.; Xu, J.; Wemmie, J. A.; Magnotta, V.
10.1101/2023.02.02.526878 — neuroscience — Posted on 2023-02-02
3857 ATM phosphorylates the FATC domain of DNA-PKcs at threonine 4102 to promote non-homologous end joining
Lu, H.; Zhang, Q.; Laverty, D. J.; Puncheon, A. C.; Williams, G. J.; Nagel, Z. D.; Chen, B. P.; Davis, A. J.
10.1101/2023.02.02.526879 — molecular biology — Posted on 2023-02-02
3860 Members of the CUGBP Elav-Like Family of RNA-Binding Proteins are Expressed in Distinct Populations of Primary Sensory Neurons
Grlickova-Duzevik, E.; Reimonn, T. M.; Michael, M.; Tian, T.; Owyoung, J. N.; McGrath-Conwell, A.; Neufeld, P. K.; Mueth, M.; Molliver, D. C.; Ward, P. J.; Harrison, B. J.
10.1101/2021.07.05.451166 — neuroscience — Posted on 2023-02-02
3863 Piperlongumine (PL) conjugates induce targeted protein degradation
Pei, J.; Xiao, Y.; Liu, X.; Hu, W.; Sobh, A.; Yuan, Y.; Zhou, S.; Hua, N.; Mackintosh, S. G.; Zhang, X.; Basso, K. B.; Kamat, M.; Yang, Q.; Licht, J. D.; Zheng, G.; Zhou, D.; Lv, D.
10.1101/2022.01.21.474712 — cancer biology — Posted on 2023-02-02
3869 Antigenic diversity in malaria parasites is maintained on extrachromosomal DNA
Ebel, E. R.; Kim, B. Y.; McDew-White, M.; Egan, E. S.; Anderson, T. J.; Petrov, D. A.
10.1101/2023.02.02.526885 — genetics — Posted on 2023-02-02
3871 Long-term effect of forest harvesting on boreal species assemblages under climate change
Bouderbala, I.; Labadie, G.; Beland, J.-M.; Tremblay, J. A.; Boulanger, Y.; Hebert, C.; Desrosiers, P.; Allard, A.; Fortin, D.
10.1101/2022.08.21.504664 — ecology — Posted on 2023-02-02
3873 Interplay between PLEKHG3-regulated actin dynamics and lysosomal trafficking in cell motility
Ettelt, R.; Vucak, G.; Didusch, S.; Riemelmoser, B.; Ehrenreiter, K.; Hartl, M.; Huber, L.; Baccarini, M.
10.1101/2023.02.01.526449 — cell biology — Posted on 2023-02-02
3874 Quercetin selectively reduces expanded repeat RNA levels in models of myotonic dystrophy
Mishra, S. K.; Hicks, S. M.; Frias, J. A.; Vangaveti, S.; Nakamori, M.; Cleary, J. D.; Reddy, K.; Berglund, J. A.
10.1101/2023.02.02.526846 — molecular biology — Posted on 2023-02-02
3877 Single-cell mass distributions reveal simple rules for achieving steady-state growth
Roller, B. R. K.; Hellerschmied, C.; Wu, Y.; Miettinen, T. P.; Manalis, S. R.; Polz, M. F.
10.1101/2023.02.02.526759 — microbiology — Posted on 2023-02-02
3878 Extravascular spaces are the primary reservoir of antigenic diversity in Trypanosoma brucei infection
Beaver, A.; Crilly, N. P.; Buenconsejo, G. Y.; Hakim, J.; Zhang, B.; Bobb, B.; Rijo-Ferreira, F.; Figueiredo, L. M.; Mugnier, M. R.
10.1101/2022.06.27.497797 — microbiology — Posted on 2023-02-02
3879 Evidence for a core set of microbial lichen symbionts from a global survey of metagenomes
Tagirdzhanova, G.; Saary, P.; Cameron, E. S.; Garber, A.; Diaz Escandon, D.; Goyette, S.; Tuovinen Nogerius, V.; Passo, A.; Mayrhofer, H.; Holien, H.; Tonsberg, T.; Stein, L. Y.; Finn, R. D.; Spribille, T.
10.1101/2023.02.02.524463 — microbiology — Posted on 2023-02-02
3885 Deep Learning-based Identification of Intraocular Pressure-Associated Genes Influencing Trabecular Meshwork Cell and Organelle Morphology
Greatbatch, C. J.; Lu, Q.; Hung, S.; Tran, S.; Wing, K.; Liang, H.; Han, X.; Zhou, T.; Siggs, O. M.; Mackey, D.; Liu, R.; Cook, A.; Powell, J.; Craig, J.; Macgregor, S.; Hewitt, A. W.
10.1101/2023.02.01.526555 — genetics — Posted on 2023-02-02
3886 Structural basis for guide RNA selection by the RESC1-RESC2 complex
Dolce, L. G.; Nesterenko, Y.; Walther, L.; Weis, F.; Kowalinski, E.
10.1101/2023.02.01.526499 — molecular biology — Posted on 2023-02-02
3889 A rapid and flexible microneutralization assay for serological assessment of influenza viruses
Rumfelt, K. E.; Fitzsimmons, W. J.; Truscon, R.; Monto, A.; Martin, E. T.; Lauring, A. S.
10.1101/2023.02.02.526820 — microbiology — Posted on 2023-02-02
3890 Imprinted anti-hemagglutinin and anti-neuraminidase antibody responses after childhood infections of A(H1N1) and A(H1N1)pdm09 influenza viruses
Daulagala, P.; Mann, B.; Leung, K.; Lau, E.; Yung, L.; Lei, R.; Nizami, S. I. N.; Wu, J. T.; Chiu, S. S.; Daniels, R. S.; Wu, N. C.; Wentworth, D. E.; Peiris, J. S. M.; Yen, H.-L.
10.1101/2023.02.01.526741 — microbiology — Posted on 2023-02-02
3891 Frequency variation and dose modification of benznidazole administration for the treatment of Trypanosoma cruzi infection in mice, dogs and non-human primates
Tarleton, R. L.; Bustamante, J.; White, B. E.; Wilkerson, G. K.; Hodo, C. L.; Aukland, L. D.; Wang, W.; McCain, S.; Hamer, S. A.; Saunders, A. B.
10.1101/2023.02.01.526739 — microbiology — Posted on 2023-02-02
3894 Discovery of a unique pathway for glutathione utilization in Francisella
Wang, Y.; Ledvina, H. E.; Tower, C. A.; Kambarev, S.; Liu, E.; Charity, J. C.; Kreuk, L. S. M.; Chen, Q.; Gallagher, L. A.; Radey, M. C.; Rerolle, G. F.; Li, Y.; Penewit, K. M.; Turkarslan, S.; Skerrett, S. J.; Salipante, S. J.; Baliga, N. S.; Woodward, J. J.; Dove, S. L.; Peterson, S. B.; Celli, J.; Mougous, J. D.
10.1101/2023.02.02.526638 — microbiology — Posted on 2023-02-02
3895 Regulation of Bacterial Two-Component Systems by Cardiolipin
Bae, T.; Yeo, W.-S.; Dyzenhaus, S.; Torres, V. J.; Brinsmade, S. R.
10.1101/2023.02.01.526740 — microbiology — Posted on 2023-02-02
3897 Microbial sensor variation across biogeochemical conditions in the terrestrial deep subsurface
Goldman, A. L.; Fulk, E. M.; Momper, L.; Heider, C.; Mulligan, J.; Osburn, M. R.; Masiello, C. A.; Silberg, J. J.
10.1101/2023.02.01.526704 — microbiology — Posted on 2023-02-02
3899 A vast evolutionarily transient translatome contributes to phenotype and fitness
Wacholder, A.; Parikh, S. B.; Coelho, N. C.; Acar, O.; Houghton, C.; Chou, L.; Carvunis, A.-R.
10.1101/2021.07.17.452746 — genomics — Posted on 2023-02-02
3901 Simultaneous identification of m6A and m5C reveals coordinated RNA modification at single-molecule resolution
Acera Mateos, P.; Sethi, A. J.; Ravindran, A.; Guarnacci, M.; Srivastava, A.; Xu, J.; Woodward, K.; Yuen, Z. W.-S.; Mahmud, S.; Kanchi, M.; Zhou, Y.; Sneddon, A.; Hamilton, W.; Gao, J.; Starrs, L. M.; Hayashi, R.; Wickramasinghe, V. O.; Zarnack, K.; Preiss, T.; Burgio, G.; Dehorter, N.; Shirokikh, N. E.; Eyras, E.
10.1101/2022.03.14.484124 — bioinformatics — Posted on 2023-02-02
3903 Modeling Flow in an In Vitro Anatomical Cerebrovascular Model with Experimental Validation
Bhardwaj, S.; Craven, B. A.; Sever, J. E.; Costanzo, F.; Simon, S. D.; Manning, K. B.
10.1101/2023.01.13.523948 — bioengineering — Posted on 2023-02-02
3906 An update on eukaryotic viruses revived from ancient permafrost
Alempic, J.-M.; Lartigue, A.; Goncharov, A. E.; Grosse, G.; Strauss, J.; Tikhonov, A. N.; Fedorov, A. N.; Poirot, O.; Legendre, M.; Santini, S.; Abergel, C.; Claverie, J.-M.
10.1101/2022.11.10.515937 — microbiology — Posted on 2023-02-02
3909 Taking stock of the past: A psychometric evaluation of the Autobiographical Interview
Lockrow, A. W.; Setton, R.; Spreng, K. A.; Sheldon, S.; Turner, G. R.; Spreng, R. N.
10.1101/2021.12.22.473803 — neuroscience — Posted on 2023-02-02
3911 Transformation of alignment files improves performance of variant callers for long-read RNA sequencing data
de Souza, V. B. C.; Jordan, B. T.; Tseng, E.; Nelson, E. A.; Hirschi, K. K.; Sheynkman, G. M.; Robinson, M. D.
10.1101/2022.02.08.479579 — bioinformatics — Posted on 2023-02-02
3914 Bioinformatic investigation of discordant sequence data for SARS-CoV-2: insights for robust genomic analysis during pandemic surveillance
Zufan, S. E.; Lau, K. A.; Donald, A.; Hoang, T.; Foster, C. S. P.; Sikazwe, C.; Theis, T.; Rawlinson, W. D.; Ballard, S. A.; Stinear, T. P.; Howden, B. P.; Jennison, A. V.; Seemann, T.
10.1101/2023.02.01.526694 — genomics — Posted on 2023-02-02
3915 EstroGene database reveals diverse temporal, context-dependent and directional estrogen receptor regulomes in breast cancer
Li, Z.; Li, T.; Yates, M. E.; Wu, Y.; Ferber, A.; Chen, L.; Brown, D. D.; Carroll, J.; Sikora, M. J.; Tseng, G.; Oesterreich, S.; LEE, A. V.
10.1101/2023.01.30.526388 — cancer biology — Posted on 2023-02-02
3916 Crystal Structures of Inhibitor-Bound Main Protease from Delta- and Gamma-Coronaviruses
Zvornicanin, S. N.; Shaqra, A. M.; Huang, Q. Y.; Ornelas, E.; Moghe, M.; Knapp, M.; Moquin, S.; Dovala, D.; Schiffer, C. A.; Kurt Yilmaz, N.
10.1101/2023.02.01.526623 — biochemistry — Posted on 2023-02-02
3917 Investigations on SARS-CoV-2 and other coronaviruses in mink farms in France at the end of the first year of COVID-19 pandemic
Wasniewski, M.; Boue, F.; Richomme, C.; Simon-Loriere, E.; Van der Werf, S.; Donati, F.; Enouf, V.; Blanchard, Y.; Beven, V.; Leperchois, E.; Leterrier, B.; Corbet, S.; Le Gouil, M.; Monchatre-Leroy, E.; Picard-Meyer, E.
10.1101/2023.02.02.526749 — microbiology — Posted on 2023-02-02
3920 Mass Spectrometry Imaging of Hair Identifies Daily Maraviroc Adherence in HPTN 069/ACTG A5305
Rosen, E. P.; White, N. R.; Gilliland, W. M.; Gerona, R.; Gandhi, M.; Amico, K. R.; Mayer, K. H.; Gulick, R. M.; Kashuba, A. D. M.
10.1101/2023.01.30.526384 — pharmacology and toxicology — Posted on 2023-02-02
3922 A comprehensive rRNA variation atlas in health and disease
Rothschild, D.; Susanto, T. T.; Spence, J. P.; Genuth, N. R.; Sinnott-Armstrong, N.; Pritchard, J. K.; Barna, M.
10.1101/2023.01.30.526360 — genetics — Posted on 2023-02-02
3926 Effects of IL2/anti-IL2 antibody complex on chikungunya virus-induced arthritis in a mouse model
Tritsch, S. R.; Porzucek, A. J.; Schwartz, A. M.; Proctor, A. M.; Amdur, R.; Latham, P. S.; Simon, G. L.; Mores, C. N.; Chang, A. Y.
10.1101/2023.01.30.526329 — immunology — Posted on 2023-02-02
3927 Organism-Wide Analysis of Sepsis Reveals Mechanisms of Systemic Inflammation
Takahama, M.; Patil, A.; Johnson, K.; Cipurko, D.; Miki, Y.; Taketomi, Y.; Carbonetto, P.; Plaster, M.; Richey, G.; Pandey, S.; Cheronis, K.; Ueda, T.; Gruenbaum, A.; Dudek, S.; Stephens, M.; Murakami, M.; Chevrier, N.
10.1101/2023.01.30.526342 — immunology — Posted on 2023-02-02
3929 Temporal regulation of AgRP neurons mediates context-induced feeding
Reed, F.; Dempsey, H.; Clarke, R.; Reichenbach, A.; Mequinion, M.; Stark, R.; Rawlinson, S.; Foldi, C.; Lockie, S.; Andrews, Z. B.
10.1101/2023.01.30.526347 — neuroscience — Posted on 2023-02-02
3932 Kv12-Encoded K+ Channels Drive the Day-Night Switch in the Repetitive Firing Rates of SCN Neurons
Hermanstyne, T. O.; Yang, N.-D.; Granados-Fuentes, D.; Li, X.; Mellor, R.; Jegla, T.; Herzog, E.; Nerbonne, J. M.
10.1101/2023.01.30.526323 — neuroscience — Posted on 2023-02-02
3933 Neural effects of TMS trains on the human prefrontal cortex
Ross, J. M.; Cline, C. C.; Sarkar, M.; Truong, J.; Keller, C. J.
10.1101/2023.01.30.526374 — neuroscience — Posted on 2023-02-02
3935 Uroprotective effect of a protein isolated from seed of Morinda citrifolia (McLTP1) on hemorrhagic cystitis induced by ifosfamide in mice
Rangel, G. d. F. P.; Cajado, A. G.; Pereira, A. F.; Rabelo, L. M. A.; Costa, A. S.; de Oliveira, H. D.; Wong, D. V. T.; Leitao, R. F. d. C.; Lima-Junior, R. C. P.; de Alencar, N. M. N.
10.1101/2023.01.30.526355 — pharmacology and toxicology — Posted on 2023-02-02
3937 Premature Aging and Reduced Cancer Incidence Associated with Body-Wide Loss of Myc
Wang, H.; Lu, J.; Stevens, T.; Roberts, A.; Mandel, J.; Avula, R.; Wu, Y.; Wang, J.; Finkel, T.; Vant Land, C.; Vockley, J. E.; Airik, M.; Airik, R.; Muzumdar, R.; Gong, Z.; Torbenson, M. S.; Prochownik, E. V.
10.1101/2023.01.30.526354 — cancer biology — Posted on 2023-02-02
3938 When do longer reads matter? A benchmark of long read de novo assembly tools for eukaryotic genomes
Cosma, B. M.; Shirali Hossein Zade, R.; Jordan, E. N.; van Lent, P.; Peng, C.; Pillay, S.; Abeel, T.
10.1101/2023.01.30.526229 — bioinformatics — Posted on 2023-02-02
3939 BIRDMAn: A Bayesian differential abundance framework that enables robust inference of host-microbe associations
Rahman, G.; Morton, J. T.; Martino, C.; Sepich-Poore, G. D.; Allaband, C.; Guccione, C.; Chen, Y.; Hakim, D.; Estaki, M.; Knight, R.
10.1101/2023.01.30.526328 — bioinformatics — Posted on 2023-02-02
3940 midiaPASEF maximizes information content in data-independent acquisition proteomics
Distler, U.; Lacki, M. K.; Startek, M. P.; Teschner, D.; Brehmer, S.; Decker, J.; Schild, T.; Krieger, J.; Krohs, F.; Raether, O.; Hildebrandt, A.; Tenzer, S.
10.1101/2023.01.30.526204 — bioinformatics — Posted on 2023-02-02
3946 Soil legacies of extreme droughts enhance the performance of invading plants
Thakur, M. P.; Sloot, M. v. d.; Wilschut, R.; Hannula, S. E.; Hooven, F. t.; Geisen, S.; Quist, C.; Steinauer, K.; Putten, W. v. d.
10.1101/2023.01.30.526304 — ecology — Posted on 2023-02-02
3949 Production of antigenically stable enterovirus A71 virus-like particles in Pichia pastoris as a vaccine candidate.
Kingston, N. J.; Snowden, J. S.; Martyna, A.; Shegdar, M.; Grehan, K.; Tedcastle, A.; Pegg, E.; Fox, H.; Macadam, A. J.; Martin, J.; Hogle, J. M.; Rowlands, D.; Stonehouse, N. J.
10.1101/2023.01.30.526315 — immunology — Posted on 2023-02-02
3950 Metabolomics reveals nucleoside analogs for regulating mucosal-associated invariant T cell responses
Huang, S.; Sharma, M.; Sallans, L.; Li, C.; Kh, Z.; Choubey, D.; Newburg, D.; Huaman, M.; Hansen, T.; Cao, S.
10.1101/2023.01.30.526332 — immunology — Posted on 2023-02-02
3951 Multiplex analysis of cytokines and chemokines in persons aging with or without HIV
Kroll, K. W.; Woolley, G.; Terry, K.; Premeaux, T. A.; Shikuma, C. M.; Corley, M. J.; Bowler, S.; Ndhlovu, L. C.; Reeves, R. K.
10.1101/2023.01.30.526135 — immunology — Posted on 2023-02-02
3955 Influence of root cortical aerenchyma on the rhizosphere microbiome of field-grown maize
Galindo-Castaneda, T.; Rojas Alvarado, C. M.; Karaoz, U.; Brodie, E. L.; Brown, K.; Lynch, J.
10.1101/2023.01.31.525837 — plant biology — Posted on 2023-02-02
3959 Plasma and liver lipids are differentially regulated after cannabinoid treatments in male and female mice
Johnson, C. T.; Bosquez-Berger, T.; Bentz, H. R.; de Abreu, G. H.; Mackie, K.; Lu, H.-C.; Bradshaw, H. B.
10.1101/2023.01.30.526249 — pharmacology and toxicology — Posted on 2023-02-02
3966 Heat-induced seizures, premature mortality, and hyperactivity in a novel Scn1a nonsense model for Dravet syndrome
Mavashov, A.; Brusel, M.; Liu, J.; Woytowicz, V.; Bae, H.; Chen, Y.-H.; Dani, V. S.; Cardenal, E.; Spinosa, V.; Aibar, J. A.; Rubinstein, M.
10.1101/2023.02.01.526678 — neuroscience — Posted on 2023-02-02
3967 MAPK11 (p38β) is a major determinant of cellular radiosensitivity by enhancing IR-associated senescence.
Fernandez-Aroca, D. M.; Garcia-Flores, N.; Frost, S.; Jimenez-Suarez, J.; Rodriguez-Gonzalez, A.; Fernandez-Aroca, P.; Sabater, S.; Andres, I.; Garnes-Garcia, C.; Belandia, B.; Cimas, F. J.; Villar, D.; Ruiz-Hidalgo, M. J.; Sanchez-Prieto, R.
10.1101/2022.09.12.506954 — cancer biology — Posted on 2023-02-02
3968 AGAP1-associated endolysosomal trafficking abnormalities link gene-environment interactions in a neurodevelopmental disorder with incomplete penetrance
Lewis, S. A.; Bakhtiari, S.; Forstrom, J.; Bayat, A.; Billan, F.; Le Guyader, G.; Alkhunaiz, E.; Vernon, H.; Padilla-Lopez, S. R.; Kruer, M. C.
10.1101/2023.01.31.526497 — genetics — Posted on 2023-02-02
3972 Abemaciclib restricts HCMV replication by suppressing pUL97-mediated phosphorylation of SAMHD1
Vavouras Syrigos, G.; Feige, M.; Dirlam, A.; Businger, R.; Gruska, I.; Wiebusch, L.; Hamprecht, K.; Schindler, M.
10.1101/2023.02.01.526617 — microbiology — Posted on 2023-02-02
3973 GADMA2: more efficient and flexible demographic inference from genetic data
Noskova, E.; Abramov, N.; Iliutkin, S.; Sidorin, A.; Dobrynin, P.; Ulyantsev, V.
10.1101/2022.06.14.496083 — bioinformatics — Posted on 2023-02-02
3974 A 3D cell-free bone model shows collagen mineralization is a physicochemical process driven and controlled by the matrix
Van der Meijden, R. H. M.; Daviran, D.; Rutten, L.; Walboomers, F.; Macias-Sanchez, E.; Sommerdijk, N.; Akiva, A.
10.1101/2022.10.24.513466 — biochemistry — Posted on 2023-02-02
3977 Automatic detection of complex structural genome variation across world populations
Zhou, B.; Arthur, J. G.; Guo, H.; Hughes, C. R.; Kim, T.; Huang, Y.; Pattni, R.; Lee, H.; Ji, H. P.; Song, G.; Palejev, D.; Zhu, X.; Wong, W. H.; Urban, A. E.
10.1101/200170 — genomics — Posted on 2023-02-02
3978 Congruent visual cues speed dynamic motor adaptation
Franklin, S.; Leib, R.; Dimitriou, M.; Franklin, D. W.
10.1101/2023.02.01.526660 — neuroscience — Posted on 2023-02-02
3985 DLK-dependent mitochondrial fission drives axon degeneration and neuronal cell death
Gomez Deza, J.; Nebiyou, M.; Alkaslasi, M. R.; Somasundaran, P.; Slavutsky, A. L.; Ward, M. E.; Watkins, T. A.; Le Pichon, C. E.
10.1101/2023.01.30.526132 — neuroscience — Posted on 2023-02-02
3988 The role of the Frontal Aslant tract in bilingual language control
Quartarone, C.; Navarrete, E.; Budisavljevic, S.; Gastaldon, S.; Peressotti, F.
10.1101/2023.02.01.526563 — neuroscience — Posted on 2023-02-02
3989 Spatially resolved multiomics of human cardiac niches
Kanemaru, K.; Cranley, J.; Muraro, D.; Miranda, A. M. A.; Pett, J. P.; Litvinukova, M.; Kumasaka, N.; Ho, S. Y.; Polanski, K.; Richardson, L.; Mach, L.; Dabrowska, M.; Richoz, N.; Barnett, S. N.; Perera, S.; Wilbrey-Clark, A. L.; Talavera-Lopez, C.; Mulas, I.; Mahbubani, K. T.; Bolt, L.; Mamanova, L.; Tuck, L.; Wang, L.; Huang, M. M.; Prete, M.; Pritchard, S.; Dark, J.; Saeb-Parsy, K.; Patel, M.; Clatworthy, M. R.; Chowdhury, R. A.; Noseda, M.; Teichmann, S. A.
10.1101/2023.01.30.526202 — genomics — Posted on 2023-02-01
3990 How to measure response diversity
Ross, S. R. P.-J.; Petchey, O. L.; Sasaki, T.; Armitage, D. W.
10.1101/2022.04.26.489626 — ecology — Posted on 2023-02-01
3993 Interplay between PLEKHG3-regulated actin dynamics and lysosomal trafficking in cell motility
Ettelt, R.; Didusch, S.; Vucak, G.; Riemelmoser, B.; Ehrenreiter, K.; Hartl, M.; Huber, L.; Baccarini, M.
10.1101/2023.02.01.526449 — cell biology — Posted on 2023-02-01
3995 Imaging dendritic spines in the hippocampus of a living mouse by 3D-STED microscopy
Bancelin, S.; Mercier, L.; Roos, J.; Belkadi, M.; Pfeiffer, T.; KIM, S. K.; Nagerl, V.
10.1101/2023.02.01.526326 — neuroscience — Posted on 2023-02-01
3996 tRNA m1G9 modification depends on substrate-specific RNA conformational changes induced by the methyltransferase Trm10
Strassler, S. E.; Bowles, I. E.; Krishnamohan, A.; Kim, H.; Kuiper, E. G.; Comstock, L.; Jackman, J. E.; Conn, G. L.
10.1101/2023.02.01.526536 — biochemistry — Posted on 2023-02-01
3998 m6A RNA methylation orchestrates transcriptional dormancy during developmental pausing
Collignon, E. A.; Cho, B.; Fothergill-Robinson, J.; Furlan, G.; Ross, R. L.; Limbach, P. A.; Ramalho-Santos, M.
10.1101/2023.01.30.526234 — developmental biology — Posted on 2023-02-01
4003 Computational modeling of DLBCL predicts response to BH3-mimetics.
Cloete, I.; Smith, V. M.; Jackson, R. A.; Pepper, A.; Pepper, C.; Vogler, M.; Dyer, M. J.; Mitchell, S.
10.1101/2023.02.01.526592 — systems biology — Posted on 2023-02-01
4005 Carcinogen induced expansion of atypical B cells and pre-treatment tumor adjacent tertiary lymphoid structures associate with poor response to BCG in non-muscle invasive bladder cancer
Yolmo, P.; Rahimi, S.; Chenard, S.; Conseil, G.; Jenkins, D.; Emon, I.; Hamilton, J.; Xu, M.; Rangachari, M.; Berman, D. M.; Siemens, D. R.; Koti, M.
10.1101/2022.12.30.522127 — cancer biology — Posted on 2023-02-01
4006 Emergent Simplicities in Stochastic Intergenerational Homeostasis
Joshi, K.; Wright, C. S.; Ziegler, K. F.; Spiers, E. M.; Crosser, J. T.; Eschker, S.; Biswas, R. R.; Iyer-Biswas, S.
10.1101/2023.01.18.524627 — biophysics — Posted on 2023-02-01
4008 High-content image-based CRISPR screening reveals regulators of 3D genome architectures
Hu, M.; Yang, B.; Jensen, T. B.; Radda, J. S. D.; Cheng, Y.; Jin, S.; Wang, S.
10.1101/2023.01.31.525983 — genetics — Posted on 2023-02-01
4011 Improving the predictive performance of CLUE-S by extending demand to land transitions: the trans-CLUE-S model
Kiziridis, D. A.; Mastrogianni, A.; Pleniou, M.; Tsiftsis, S.; Xystrakis, F.; Tsiripidis, I.
10.1101/2023.01.10.523486 — ecology — Posted on 2023-02-01
4013 Antimicrobial overproduction sustains intestinal inflammation by inhibiting Enterococcus colonization
Jang, K. K.; Heaney, T.; London, M.; Ding, Y.; Yeung, F.; Ercelen, D.; Chen, Y.-H.; Axelrad, J.; Gurunathan, S.; Keestra-Gounde, A. M.; Griffin, M. E.; Hang, H. C.; Cadwell, K.
10.1101/2023.01.29.526128 — immunology — Posted on 2023-02-01
4014 A versatile Synaptotagmin-1 nanobody provides perturbation-free live synaptic imaging and low linkage-error in super-resolution microscopy
Queiroz Zetune Villa Real, K.; Mougios, N.; Rehm, R.; Sograte-Idrissi, S.; Albert, L.; Rahimi, A. M.; Maidorn, M.; Hentze, J.; Martinez-Carranza, M.; Hosseini, H.; Saal, K. A.; Oleksiievets, N.; Prigge, M.; Tsukanov, R.; Stenmark, P.; Fornasiero, E. F.; Opazo, F.
10.1101/2023.01.30.525828 — neuroscience — Posted on 2023-02-01
4015 Functional Trajectories during innate spinal cord repair
Jensen, N. O.; Burris, B.; Zhou, L.; Yamada, H.; Reyes, C.; Mokalled, M. H.
10.1101/2023.01.31.526502 — neuroscience — Posted on 2023-02-01
4016 Continuous automated analysis workflow for MRS studies
Zoellner, H. J.; Davies-Jenkins, C. W.; Lee, E. G.; Hendrickson, T. J.; Clarke, W. T.; Edden, R. A.; Wisnowski, J. L.; Gudmundson, A. T.; Oeltzschner, G.
10.1101/2022.11.03.515056 — neuroscience — Posted on 2023-02-01
4018 A fungal endophyte-generated nucleoside signal regulates host cell death and promotes root colonization
Dunken, N.; Widmer, H.; Balcke, G. U.; Straube, H.; Langen, G.; Charura, N. M.; Saake, P.; De Quattro, C.; Schoen, J.; Roevenich, H.; Wawra, S.; Djamei, A.; Zurbriggen, M. D.; Tissier, A. F.; Witte, C.-P. F.; Zuccaro, A.
10.1101/2022.03.11.483938 — plant biology — Posted on 2023-02-01
4020 Inferring CTCF binding patterns and anchored loops across human tissues and cell types
Xu, H.; Yi, X.; Wang, W.; Chu, X.; Huang, D.; Zhang, S.; Dong, X.; Wang, Z.; Wang, J.; Zhou, Y.; Zhao, K.; Yao, H.; Wang, J.; Chen, K.; Plewczynski, D.; Sham, P. C.; Li, M. J.
10.1101/2022.06.15.496356 — bioinformatics — Posted on 2023-02-01
4022 Efficient and highly amplified imaging of nucleic acid targets in cellular and histopathological samples with pSABER
Attar, S.; Browning, V. E.; Liu, Y.; Nichols, E. K.; Tsue, A. F.; Shechner, D. M.; Shendure, J.; Lieberman, J. A.; Akilesh, S.; Beliveau, B. J.
10.1101/2023.01.30.526264 — genomics — Posted on 2023-02-01
4025 Zyxin contributes to coupling between cell junctions and contractile actomyosin networks during apical constriction
Slabodnick, M. M.; Tintori, S. C.; Prakash, M.; Zhang, P.; Higgins, C. D.; Chen, A. H.; Cupp, T. D.; Wong, T.; Bowie, E.; Jug, F.; Goldstein, B.
10.1101/2022.07.04.498649 — genetics — Posted on 2023-02-01
4026 Evaluating the mouse neural precursor line, SN4741, as a suitable proxy for midbrain dopaminergic neurons
Boyd, R. J.; McClymont, S. A.; Barrientos, N. B.; Hook, P. W.; Law, W. D.; Rose, R. J.; Waite, E. L.; Avramopoulos, D.; McCallion, A. S.
10.1101/2023.01.23.525270 — genetics — Posted on 2023-02-01
4027 Mitotic heritability of DNA methylation at intermediately methylated sites is imprecise
Hay, A. D.; Kessler, N. J.; Gebert, D.; Takahashi, N.; Tavares, H.; Karam Teixeira, F.; Ferguson-Smith, A. C.
10.1101/2023.01.27.525699 — genetics — Posted on 2023-02-01
4031 Dynamic interplay between RPL3- and RPL3L-containing ribosomes modulates mitochondrial activity in the mammalian heart
Milenkovic, I.; Santos Vieira, H. G.; Lucas, M. C.; Ruiz-Orera, J.; Patone, G.; Kesteven, S.; Wu, J.; Feneley, M.; Espadas, G.; Sabido, E.; Hubner, N.; van Heesch, S.; Voelkers, M.; Novoa, E. M.
10.1101/2021.12.04.471171 — molecular biology — Posted on 2023-02-01
4032 Metaproteomic analysis of nasopharyngeal swab samples to identify microbial peptides and potential co-infection status in COVID-19 patients
Bihani, S.; Gupta, A.; Mehta, S.; Rajczewski, A.; Johnson, J.; Borishetty, D.; Griffin, T. J.; Srivastava, S.; Jagtap, P.
10.1101/2023.01.31.525328 — microbiology — Posted on 2023-02-01
4034 Polypharmacology-based kinome screen identifies new regulators of KSHV reactivation
Olson, A. T.; Kang, Y.; Ladha, A. M.; Lim, C. B.; Lagunoff, M.; Gujral, T. S.; Geballe, A. P.
10.1101/2023.02.01.526589 — microbiology — Posted on 2023-02-01
4036 Eukaryotic-like gephyrin and cognate membrane receptor coordinate corynebacterial cell division and polar elongation.
Martinez, M.; Petit, J.; Leyva, A.; Sogues Castrejon, A.; Megrian, D.; Rodriguez, A.; Gaday, Q.; Ben Assaya, M.; Portela, M. M.; Haouz, A.; Ducret, A.; Grangeasse, C.; Alzari, P. M.; Duran, R.; Wehenkel, A. M.
10.1101/2023.02.01.526586 — microbiology — Posted on 2023-02-01
4039 An integrative and multi-indicator approach for wildlife health applied to an endangered caribou herd
Fernandez Aguilar, X.; Leclerc, L. M.; Association, K. A.; Organization, E. H. T.; Committee, O. H. & T.; Mavrot, F.; Roberto-Charron, A.; Tomaselli, M.; Mastromonaco, G.; Gunn, A.; Pruvot, M.; Rothenburger, J. L. R.; Thanthrige-Don, N.; Zeini Jahromi, E.; Kutz, S.
10.1101/2023.02.01.526641 — microbiology — Posted on 2023-02-01
4042 SPI-1 virulence gene expression modulates motility of Salmonella Typhimurium in a proton motive force- and adhesins-dependent manner
Osama Saleh, D.; Horstmann, J. A.; Giralt-Zuniga, M.; Weber, W.; Durai Raj, A. C.; Klotzsch, E.; Strowig, T.; Erhardt, M.
10.1101/2023.02.01.526580 — microbiology — Posted on 2023-02-01
4043 Genetic profiling of Plasmodium ovale wallikeri relapses with microsatellite markers and whole-genome sequencing
Joste, V.; Colard-Itte, E.; Guillochon, E.; Ariey, F.; Coppee, R.; Clain, J.; Houze, S.; French National Reference Center for Imported Malaria Study Group,
10.1101/2023.02.01.526392 — microbiology — Posted on 2023-02-01
4046 Increasingly divergent responses to infection in mice suggest B cell evolution is not constrained by germline-encoded specificities
Vieira, M. C.; Palm, A.-K. E.; Stamper, C. T.; Tepora, M. E.; Nguyen, K. D.; Pham, T. D.; Boyd, S. D.; Wilson, P. C.; Cobey, S.
10.1101/2022.09.16.508315 — immunology — Posted on 2023-02-01
4049 Transcriptomic analyses reveal prenatal stress promotes late-onset neural stem cell proliferation in adult male offspring
Wang, Z.; Zhou, L.; Lee, C.; Shi, J.; Liu, L.; Yang, X.; Deng, Y.; Liu, J.; Wang, J.; Zhu, W.; Sun, Y. E.; Lin, Q.
10.1101/2022.12.15.520572 — neuroscience — Posted on 2023-02-01
4050 GNOM-Dependent Endosomal Recycling Sets the Timing of Founder Cell Specification
Perez-Garcia, P.; Perianez-Rodriguez, J.; Sanchez-Corrionero, A.; Moreno-Risueno, M.-A.
10.1101/2023.01.31.526479 — plant biology — Posted on 2023-02-01
4051 Mass spectrometry-based proteomics imputation using self supervised deep learning
Webel, H.; Niu, L.; Bach Nielsen, A.; Locard-Paulet, M.; Mann, M.; Juhl Jensen, L.; Rasmussen, S.
10.1101/2023.01.12.523792 — bioinformatics — Posted on 2023-02-01
4052 Molecular drivers of insecticide resistance in the Sahelo-Sudanian populations of a major malaria vector Anopheles coluzzii
Ibrahim, S. S.; Muhammad, A.; Hearn, J.; Weedall, G. D.; Nagi, S. C.; Mukhtar, M. M.; Fadel, A. N.; Mugenzi, L. J.; Patterson, E. I.; Irving, H.; Wondji, C. S.
10.1101/2022.03.21.485146 — genomics — Posted on 2023-02-01
4054 A>G substitutions on a heavy chain of mitochondrial genome marks an increased level of aerobic metabolism in warm versus cold vertebrates .
Mikhailova, A. G.; Iliushchenko, D.; Shamanskiy, V.; Mihailova, A. A.; Ushakova, K.; Tretiakov, E.; Oreshkov, S.; Knorre, D.; Polishchuk, L.; Lawless, D.; Kuzmin, A.; Denisov, S.; Kozenkov, I.; Mazunin, I.; Kunz, W.; Tanaka, M.; Makeev, V.; Castilho, R.; Yurov, V.; Kuptsov, A.; Fellay, J. S.; Khrapko, K.; Gunbin, K.; Popadin, K.
10.1101/2020.07.25.221184 — evolutionary biology — Posted on 2023-02-01
4056 Selective pressure by rifampicin modulates mutation rates and evolutionary trajectories of mycobacterial genomes
Cebrian-Sastre, E.; Chiner-Oms, A.; Torres-Perez, R.; Comas, I.; Oliveros, J. C.; Blazquez, J.; Castaneda-Garcia, A.
10.1101/2023.02.01.525872 — microbiology — Posted on 2023-02-01
4058 EXPANSION OF ANTIGEN- SPECIFIC MEMORY CELLS AS A POTENTIAL BOOSTER FOR FOOD TOLERANCE INDUCTION
Pereira e Silva, A.; Marmello, B. O.; Bentes, A.; Faccini, C. R. J. d. N.; Rodrigues, S. K. P. M.; Soares, J. R. A.; Teixeira, G.
10.1101/2023.01.30.526302 — immunology — Posted on 2023-02-01
4059 MNRR1 activation by nitazoxanide abrogates lipopolysaccharide- induced preterm birth in mice
Purandare, N.; Gomez-Lopez, N.; Arenas-Hernandez, M.; Galaz, J.; Romero, R.; Xi, Y.; Fribley, A.; Grossman, L. I.; Aras, S.
10.1101/2023.01.30.525762 — immunology — Posted on 2023-02-01
4060 CD39+ conventional CD4+ T cells with exhaustion traits and cytotoxic potential infiltrate tumors and expand upon CTLA-4 blockade
Bossio, S. N.; Abrate, C.; Tosello Boari, J.; Rodriguez, C.; Canale, F.; Ramello, M. C.; Richer, W.; Rocha, D.; Sedlik, C.; Salomon, A.; Borcoman, E.; del Castillo, A.; Gruppi, A.; Fernandez, E.; Acosta Rodriguez, E. V.; Montes, C. L.
10.1101/2023.01.30.526262 — immunology — Posted on 2023-02-01
4061 IL-15 synergizes with CD40 agonist antibodies to induce durable immunity against bladder cancer
Wong, J. L.; Smith, P.; Angulo-Lozano, J.; Ranti, D.; Bochner, B.; Sfakianos, J. P.; Horowitz, A.; Ravetch, J. V.; Knorr, D.
10.1101/2023.01.30.526266 — immunology — Posted on 2023-02-01
4062 Power analysis for human melatonin suppression experiments
Spitschan, M.; Vidafar, P.; Cain, S. W.; Phillips, A. J. K.; Lambert, B. C.
10.1101/2023.01.30.526303 — neuroscience — Posted on 2023-02-01
4064 Spectral signatures of cross-modal attentional control in the adolescent brain and their link with physical activity and aerobic fitness levels
Hernandez, D.; Kujala, J.; Heinila, E.; Ruotsalainen, I.; Lapinkero, H.-M.; Syvaoja, H.; Parkkonen, L.; Tammelin, T. H.; Parviainen, T.
10.1101/2023.01.30.526274 — neuroscience — Posted on 2023-02-01
4065 Characterizing transcriptomic responses to sediment stress across location and morphology in reef-building corals
Ashey, J.; McKelvie, H.; Freeman, J. D.; Shpilker, P.; Zane, L. H.; Becker-Polinski, D. M.; Cowen, L.; Richmond, R. H.; Paul, V.; Seneca, F.; Putnam, H. M.
10.1101/2023.01.30.526279 — bioinformatics — Posted on 2023-02-01
4066 Near infrared conjugated polymer nanoparticles (CPN) for tracking cells using fluorescence and optoacoustic imaging
Muniz-Garcia, A.; Hernandez-Pichardo, A.; Littlewood, J.; Sharkey, J.; Wilm, B.; Peace, H.; O Callaghan, D.; Green, M.; Taylor, A.; Murray, P.
10.1101/2023.01.30.526261 — bioengineering — Posted on 2023-02-01
4067 Programmable peroxidase-assisted signal amplification enables flexible detection of nucleic acid targets in cellular and histopathological specimens
Attar, S.; Browning, V. E.; Liu, Y.; Nichols, E. K.; Tsue, A. F.; Shechner, D. M.; Shendure, J.; Lieberman, J. A.; Akilesh, S.; Beliveau, B. J.
10.1101/2023.01.30.526264 — genomics — Posted on 2023-02-01
4068 Skin microbiome attributes associate with biophysical skin aging
Zhou, W.; Fleming, E.; Legendre, G.; Roux, L.; Latreille, J.; Gendronneau, G.; Forestier, S.; Oh, J.
10.1101/2023.01.30.526239 — genomics — Posted on 2023-02-01
4069 Sustainable land management enhances ecological and economic multifunctionality under ambient and future climate
Scherzinger, F.; Schädler, M.; Reitz, T.; Yin, R.; Auge, H.; Merbach, I.; Roscher, C.; Harpole, S.; Berger, S.; Blagodatskaya, E.; Siebert, J.; Ciobanu, M.; Eisenhauer, N.; Quaas, M.
10.1101/2023.01.30.525902 — ecology — Posted on 2023-02-01
4070 Tregs constrain CD8+ T cell priming required for curative intratumorally anchored anti-4-1BB immunotherapy
Palmeri, J. R.; Lax, B. M.; Peters, J. M.; Duhamel, L. R.; Stinson, J. A.; Santollani, L.; Lutz, E. A.; Pinney, W.; Bryson, B. D.; Wittrup, K. D.
10.1101/2023.01.30.526116 — immunology — Posted on 2023-02-01
4075 The plasma degradome reflects later development of NASH fibrosis after liver transplant
Li, J.; Sato, T.; Hernandez-Tejero, M.; Beier, J. I.; Sayed, K.; Benos, P. V.; Wilkey, D. W.; Humar, A.; Merchant, M. L.; Duarte-Rojo, A.; Arteel, G. E.
10.1101/2023.01.30.526241 — pathology — Posted on 2023-02-01
4078 Analysis of the Distal Urinary Tract in Larval and Adult Zebrafish Reveals Unrecognized Homology to the Human System
Jubber, I.; Morhardt, D. R.; Griffin, J.; Cumberbatch, M. G.; Glover, M.; Zheng, Y.; Rehman, I.; Loynes, C. A.; Hussain, S. A.; Leach, S. D.; Renshaw, S.; Cunliffe, V. T.; Catto, J. W.
10.1101/2023.01.30.526174 — evolutionary biology — Posted on 2023-02-01
4079 Quantifying invasive pest dynamics through inference of a two-node epidemic network model
Wadkin, L. E.; Golightly, A.; Branson, J.; Hoppit, A.; Parker, N. G.; Baggaley, A. W.
10.1101/2023.01.30.526176 — ecology — Posted on 2023-02-01
4080 Generation and expansion of transitional lung organoids from human pluripotent stem cells
Snoeck, H.-W.; Matkovic Leko, I.; Schrode, N.; Pezet, M. G.; Thimraj, T. A.; Beaumont, K.; Torres, J. A.
10.1101/2023.01.30.526265 — cell biology — Posted on 2023-02-01
4081 Remodeling of the Ribosomal Quality Control and Protein Translation by a Viral Ubiquitin Deconjugase
Liu, J.; Nagy, N.; Aguilar-Alonso, F.; Esteves, F.; Ayala-Torres, C.; Xu, S.; Masucci, M. G.
10.1101/2023.01.31.526464 — cell biology — Posted on 2023-02-01
4085 Human Abdominal Subcutaneous-Derived Active Beige Adipocytes Carrying FTO rs1421085 Obesity-Risk Alleles Exert Lower Thermogenic Capacity
Vamos, A.; Arianti, R.; Vinnai, B. A.; Alrifai, R.; Shaw, A.; Poliska, S.; Guba, A.; Csosz, E.; Csomos, I.; Mocsar, G.; Lanyi, C.; Balajthy, Z.; Fesüs, L.; Kristof, E.
10.1101/2023.01.30.525688 — cell biology — Posted on 2023-02-01
4086 A new microphysiological system shows hypoxia primes human ISCs for interleukin-dependent rescue of stem cell activity
Rivera, K. R.; Bliton, R. J.; Burclaff, J.; Czerwinski, M. J.; Liu, J.; Trueblood, J. M.; Hinesley, C.; Breau, K. A.; Joshi, S.; Pozdin, V. A.; Yao, M.; Ziegler, A. L.; Blikslager, A. T.; Daniele, M.; Magness, S.
10.1101/2023.01.31.524747 — cell biology — Posted on 2023-02-01
4087 Identification of two β-cell subtypes by 7 independent criteria
Dror, E.; Fagnocchi, L.; Wegert, V.; Apostle, S.; Grimaldi, B.; Gruber, T.; Panzeri, I.; Heyne, S.; Hoeffler, K. D.; Kreiner, V.; Ching, R.; Lu, T. T.-H.; Semwal, A.; Johnson, B.; Senapati, P.; Lempradl, A. M.; Schones, D.; Imhof, A.; Shen, H.; Pospisilik, J. A.
10.1101/2023.01.31.526222 — cell biology — Posted on 2023-02-01
4088 A versatile synaptotagmin-1 nanobody provides perturbation-free live synaptic imaging and low linkage-error in super-resolution microscopy
Queiroz Zetune Villa Real, K.; Mougios, N.; Rehm, R.; Sograte-Idrissi, S.; Albert, L.; Rahimi, A. M.; Maidorn, M.; Martinez-Carranza, M.; Hosseini, H.; Saal, K. A.; Oleksiievets, N.; Prigge, M.; Tsukanov, R.; Stenmark, P.; Fornasiero, E. F.; Opazo, F.
10.1101/2023.01.30.525828 — neuroscience — Posted on 2023-02-01
4089 Live imaging of excitable axonal microdomains in ankyrin-G-GFP mice
Thome, C.; Janssen, J. M.; Karabulut, S.; Acuna, C.; D'Este, E.; Soyka, S. J.; Baum, K.; Bock, M.; Lehmann, N.; Ganea, D. A.; Benoit, C. M.; Gründemann, J.; Schultz, C.; Bennett, V.; Jenkins, P. M.; Engelhardt, M.
10.1101/2023.02.01.525891 — neuroscience — Posted on 2023-02-01
4091 Translational control of furina by an RNA regulon is essential for heart morphogenesis and cardiac valve function
Nagorska, A.; Lambert, F.; Inman, A.; Toral-Perez, S.; Zaucker, A.; Gorodkin, J.; Wan, Y.; Smutny, M.; Sampath, K.
10.1101/2023.01.30.526270 — developmental biology — Posted on 2023-02-01
4092 p16-dependent upregulation of PD-L1 impairs immunosurveillance of senescent cells
Majewska, J.; Agrawal, A.; Mayo, A.; Roitman, L.; Chatterjee, R.; Kralova, J.; Landsberger, T.; Katzenelenbogen, Y.; Salame, T. M.; Hagai, E.; Stanojevic, N.; Amit, I.; Alon, U.; Krizhanovsky, V.
10.1101/2023.01.30.524522 — cell biology — Posted on 2023-02-01
4094 Activation of Ca2+ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy
Marchesan, E.; Nardin, A.; Mauri, S.; Di Paola, S.; Chinellato, M.; von Stockum, S.; Chakraborty, J.; Herkenne, S.; Basso, V.; Schrepfer, E.; Marin, O.; Cendron, L.; Medina, D. L.; Scorrano, L.; Ziviani, E.
10.1101/2023.01.31.526442 — cell biology — Posted on 2023-02-01
4096 Perforin-2 is a pore-forming effector of endocytic escape in cross- presenting dendritic cells
Rodriguez-Silvestre, P.; Laub, M.; Davies, A. K.; Schessner, J. P.; Krawczyk, P. A.; Tuck, B. J.; McEwan, W. A.; Borner, G. H. H.; Kozik, P.
10.1101/2023.01.31.525875 — cell biology — Posted on 2023-02-01
4097 Single cell DNA methylation ageing in mouse blood
Bonder, M. J.; Clark, S.; Krueger, F.; Luo, S.; Agostinho de Sousa, J.; Hashtroud, A. M.; Stubbs, T. M.; Stark, A.-K.; Rulands, S.; Stegle, O.; Reik, W.; von Meyenn, F.
10.1101/2023.01.30.526343 — cell biology — Posted on 2023-02-01
4098 Human ovarian ageing is characterized by oxidative damage and mitochondrial dysfunction
Smits, M. A. J.; Schomakers, B. V.; van Weeghel, M.; Wever, E. J. M.; Wust, R. C. I.; Dijk, F.; Janssens, G. E.; Goddijn, M.; Mastenbroek, S.; Houtkooper, R.; Hamer, G.
10.1101/2023.01.31.525662 — cell biology — Posted on 2023-02-01
4099 Mesenchymal Stromal Cell secretome is affected by tissue source, donor age and sex.
Turlo, A. J.; Hammond, D. E.; Ramsbottom, K. A.; Soul, J.; Gillen, A.; McDonald, K.; Peffers, M. J.; Clegg, P. D.
10.1101/2023.01.30.526247 — cell biology — Posted on 2023-02-01
4100 A role for the V0 sector of the V-ATPase in neuroexocytosis: exogenous V0d blocks complexin and SNARE interactions with V0c
LEVEQUE, C.; MAULET, Y.; WANG, Q.; RAME, M.; MOCHIDA, S.; SANGIARDI, M.; YOUSSOUF, F.; IBORRA, C.; SEAGAR, M.; VITALE, N.; EL FAR, O.
10.1101/2023.01.31.526435 — cell biology — Posted on 2023-02-01
4101 Mucociliary Clearance Augmenting Drugs Block SARS-Cov-2 Replication in Human Airway Epithelial Cells
Campos-Gomez, J.; Fernandez Petty, C.; Mazur, M.; Tang, L.; Solomon, G. M.; Joseph, R.; Li, Q.; Peabody Lever, J. E.; Hussain, S. S.; Harrod, K. S.; Onuoha, E.; Kim, H.; Rowe, S. M.
10.1101/2023.01.30.526308 — microbiology — Posted on 2023-02-01
4102 Cyclical control of female rejection behavior by progesterone receptor expressing neurons of the anterior ventromedial hypothalamus
Gutierrez-Castellanos, N.; Husain, B. F. A.; Dias, I. C.; Nomoto, K.; Duarte, M. A.; Ferreira, L.; Lacoste, B.; Lima, S. Q.
10.1101/2023.01.30.526259 — neuroscience — Posted on 2023-02-01
4104 Glucose deprivation promotes pseudo-hypoxia and de-differentiation in lung adenocarcinoma
Saggese, P.; Pandey, A.; Fung, E.; Hall, A.; Yanagawa, J.; Rodriguez, E. F.; Grogan, T. R.; Giurato, G.; Nassa, G.; Salvati, A.; Weisz, A.; Dubinett, S. M.; Scafoglio, C.
10.1101/2023.01.30.526207 — cancer biology — Posted on 2023-02-01
4111 Stochastic dispersal assembly dominates tropical invertebrate community assembly regardless of land use intensity.
Granville, N. R.; Barclay, M. V. L.; Boyle, M. J. W.; Fayle, T. M.; Hardwick, J. L.; Kinneen, L.; Kitching, R. L.; Maunsell, S. C.; Miller, J. A.; Sharp, A. C.; Stork, N. E.; Ewers, R. M.
10.1101/2023.01.30.526177 — ecology — Posted on 2023-02-01
4112 M-CSF induces a coordinated myeloid and NK cell differentiation program protecting against CMV after hematopoietic cell transplantation
Kandalla, P. K.; Subburayalu, J.; Cocita, C.; de Laval, B.; Tomasello, E.; Iacono, J.; Nitsche, J.; Canali, M. M.; Cathou, W.; Bessou, G.; Mossadegh-Keller, N.; Huber, C.; Sarrazin, S.; Mouchiroud, G.; Bourette, R.; Grasset, M.-F.; Dalod, M.; Sieweke, M. H.
10.1101/2023.01.30.526105 — immunology — Posted on 2023-02-01
4116 TXNIP in liver sinusoidal endothelial cells ameliorates alcohol-associated liver disease
Jung, E.; Baek, E. B.; Hong, E.-J.; Kang, J. H.; Park, S.; Hong, E.-J.; Cho, Y.-E.; Ko, J.-W.; Won, Y.-S.; Kwon, H.-J.
10.1101/2023.01.30.526192 — pathology — Posted on 2023-02-01
4117 Colour patterns are less variable in highly unpalatable nudibranchs
van den Berg, C.; Endler, J. A.; Drummond, L.; Dawson, B.; Santiago, C.; Weber, N.; Cheney, K. L.
10.1101/2023.01.30.525844 — animal behavior and cognition — Posted on 2023-02-01
4121 ARHGAP29 is required for keratinocyte proliferation and migration
Reeb, T.; Rhea, L.; Adelizzi, E.; Garnica, B.; Dunnwald, E.; Dunnwald, M.
10.1101/2023.01.30.525978 — cell biology — Posted on 2023-02-01
4123 The distance between the plasma membrane and the actomyosin cortex acts as a nanogate to control cell surface mechanics
Lembo, S.; Strauss, L.; Cheng, W. C. D.; Vermeil, J.; Siggel, M.; Toro-Nahuelpan, M.; Chan, C. J.; Kosinski, J.; Piel, M.; Du Roure, O.; Heuvingh, J.; Mahamid, J.; Diz-Munoz, A.
10.1101/2023.01.31.526409 — biophysics — Posted on 2023-02-01
4125 The role of pneumococcal extracellular vesicles on the pathophysiology of the kidney disease Hemolytic Uremic Syndrome
Battista, M.; Hoffmann, B.; Bachelot, Y.; Zimmermann, L.; Teuber, L.; Jost, A.; Linde, S.; Westermann, M.; Müller, M. M.; Slevogt, H.; Hammerschmidt, S.; Figge, M. T.; Vilhena, C.; Zipfel, P. F.
10.1101/2023.01.30.526387 — microbiology — Posted on 2023-02-01
4128 Molecular portraits of colorectal cancer morphological regions
Budinska, E.; Hrivnakova, M.; Catela Ivkovic, T.; Madrzyk, M.; Nenutil, R.; Bencsikova, B.; Al Tukmachi, D.; Ruckova, M.; Zdrazilova Dubska, L.; Slaby, O.; Feit, J.; Dragomir, M.-P.; Borilova Linhartova, P.; Tejpar, S.; Popovici, V.
10.1101/2023.01.24.525310 — cancer biology — Posted on 2023-02-01
4132 Characterization of undocumented CO2 hydrothermal vent s system in the Mediterranean Sea:implications for ocean acidification forecasting
D'Alessandro, M.; Gambi, M. C.; Caruso, C.; Di Bella, M.; Esposito, V.; Gattuso, A.; Giacobbe, S.; Kralj, M.; Italiano, F.; Lazzaro, G.; Sabatino, G.; de Vittor, C.; Bazzarro, M.
10.1101/2022.10.27.513997 — ecology — Posted on 2023-02-01
4133 Novel emm4 lineage associated with an upsurge in invasive group A streptococcal disease in the Netherlands, 2022
van der Putten, B. C.; Bril-Keijzers, W. C.; Rumke, L. W.; Vestjens, S. M. T.; Koster, L. A.; Willemsen, M.; Vlaminckx, B. J. M.; de Gier, B.; van Sorge, N. M.
10.1101/2022.12.31.522331 — microbiology — Posted on 2023-02-01
4135 MPK12 in stomatal CO2 signaling: function beyond its kinase activity
Yeh, C. -Y.; Wang, Y.-S.; Takahashi, Y.; Kuusk, K.; Paul, K.; Arjus, T.; Yadlos, O.; Schroeder, J. I.; Ilves, I.; Garcia-Sosa, A. T.; Kollist, H.
10.1101/2023.01.31.526436 — plant biology — Posted on 2023-02-01
4136 A one-stage approach for the spatio-temporal analysis of high-throughput phenotyping data
Perez-Valencia, D. M.; Rodriguez-Alvarez, M. X.; Boer, M. P.; van Eeuwijk, F. A.
10.1101/2023.01.31.526411 — genetics — Posted on 2023-02-01
4138 Two teosintes made modern maize
Yang, N.; Wang, Y.; Liu, X.; Jin, M.; Vallebueno-Estrada, M.; Calfee, E.; Chen, L.; Dilkes, B. P.; Gui, S.; Fan, X.; Harper, T. K.; Kennett, D. J.; Li, W.; Lu, Y.; Luo, J.; Mambakkam, S.; Menon, M.; Snodgrass, S.; Veller, C.; Wu, S.; Wu, S.; Xiao, Y.; Yang, X.; Stitzer, M.; Runcie, D.; Yan, J.; Ross-Ibarra, J.
10.1101/2023.01.31.526540 — evolutionary biology — Posted on 2023-02-01
4139 Chromosome-level genomes of multicellular algal sisters to land plants illuminate signaling network evolution
Feng, X.; Zheng, J.; Irisarri, I.; Yu, H.; Zheng, B.; Ali, Z.; de Vries, S.; Keller, J.; Fuerst-Jansen, J. M.; Dadras, A.; Zegers, J. M.; Rieseberg, T. P.; Dhabalia Ashok, A.; Darienko, T.; Bierenbroodspot, M. J.; Gramzow, L.; Petroll, R.; Haas, F. B.; Fernandez-Pozo, N.; Nousias, O.; Li, T.; Fitzek, E.; Grayburn, W. S.; Rittmeier, N.; Permann, C.; Ruempler, F.; Archibald, J. M.; Theissen, G.; Mower, J. P.; Lorenz, M.; Buschmann, H.; von Schwartzenberg, K.; Boston, L.; Hayes, R. D.; Daum, C.; Barry, K.; Grigoriev, I. V.; Wang, X.; Li, F.-W.; Rensing, S. A.; Ben-Ari, J.; Keren, N.; Mosquna, A.;
10.1101/2023.01.31.526407 — evolutionary biology — Posted on 2023-02-01
4141 GNOM-Dependent Endosomal Recycling Sets the Timing of Founder Cell Specification
Perez-Garcia, P.; Moreno-Risueno, M.-A.; Perianez-Rodriguez, J.; Sanchez-Corrionero, A.
10.1101/2023.01.31.526479 — plant biology — Posted on 2023-02-01