bioRxiv directory

Klein, H.-U.; McCabe, C.; Gjoneska, E.; Sullivan, S. E.; Kaskow, B. J.; Tang, A.; Smith, R. V.; Xu, J.; Pfenning, A. R.; Bernstein, B. E.; Meissner, A.; Schneider, J. A.; Mostafavi, S.; Tsai, L.-H.; Young-Pearse, T. L.; Bennett, D. A.; De Jager, P. L.

10.1101/273789 — neuroscience — Posted on 2018-02-28

22 Target specific routing of visual information by the superior colliculus

Reinhard, K.; Li, C.; Do, Q.; Burke, E.; Heynderickx, S.; Farrow, K.

10.1101/272914 — neuroscience — Posted on 2018-02-28

23 Genome-wide diversity in temporal and regional populations of the betabaculovirus Erinnyis ello granulovirus (ErelGV)

Brito, A. F.; Melo, F. L.; Ardisson-Araujo, D. M.; Sihler, W.; Souza, M. L.; Ribeiro, B. M.

10.1101/273672 — genomics — Posted on 2018-02-28

24 Sci-LMM is an efficient strategy for inferring genetic variance components using population scale family trees

Shor, T.; Geiger, D.; Erlich, Y.; Weissbrod, O.

10.1101/256396 — genetics — Posted on 2018-02-28

25 Discovering patterns of pleiotropy in genome-wide association studies

Zhan, J.; Arking, D. E.; Bader, J. S.

10.1101/273540 — genetics — Posted on 2018-02-28

26 Sexual selection and inbreeding: two efficient ways to limit the accumulation of deleterious mutations

Noel, E.; Fruitet, E.; Lelaurin, D.; Bonel, N.; Segard, A.; Sarda, V.; Jarne, P.; David, P.

10.1101/273367 — evolutionary biology — Posted on 2018-02-28

27 Towards a unification of niche and neutral models of community ecology

Laan, A.; de Polavieja, G.

10.1101/273664 — ecology — Posted on 2018-02-28

28 The ecology of the Drosophila-yeast mutualism in wineries

Quan, A. S.; Eisen, M. B.

10.1101/273839 — ecology — Posted on 2018-02-28

29 Dietary lipids modulate Notch signaling and influence adult intestinal development and metabolism in Drosophila

Obniski, R.; Sieber, M.; Spradling, A. C.

10.1101/273813 — developmental biology — Posted on 2018-02-28

30 An Array of Gut-on-a-Chips for Drug Development

Ashammakhi, N.; Elmusrati, M.

10.1101/273847 — cell biology — Posted on 2018-02-28

31 Collagen stiffness modulates MDA-MB231 cell metabolism through adhesion-mediated contractility

Mah, E. J.; McGahey, G. E.; Yee, A. F.; Digman, M. A.

10.1101/272948 — cancer biology — Posted on 2018-02-28

32 Microbiome-TP53 Gene Interaction in Human Lung Cancer

Greathouse, K. L.; White, J. R.; Vargas, A. J.; Bliskovsky, V. V.; Beck, J. A.; von Muhlinen, N.; Polley, E. C.; Bowman, E. D.; Khan, M. A.; Robles, A. I.; Cooks, T.; Ryan, B. M.; Dzutsev, A. H.; Trinchieri, G.; Pineda, M. A.; Bilke, S.; Meltzer, P. S.; Hokenstad, A. N.; Stickrod, T. M.; Walther-Antonio, M. R.; Earl, J. P.; Mell, J. C.; Krol, J. E.; Balashov, S. V.; Bhat, A. S.; Ehrlich, G. D.; Valm, A.; Deming, C.; Conlan, S.; Oh, J.; Segre, J. A.; Harris, C. C.

10.1101/273524 — cancer biology — Posted on 2018-02-28

33 NMR Protein Structure Determination via Local Conformational Mapping

ElGamacy, M.; Riss, M.; Zhu, H.; Truffault, V.; Coles, M.

10.1101/273607 — biophysics — Posted on 2018-02-28

34 Tumor-specific Causal Inference (TCI): A Bayesian Method for Identifying Causative Genome Alterations within Individual Tumors

Cooper, G.; Cai, C.; Lu, X.

10.1101/225631 — bioinformatics — Posted on 2018-02-28

35 Testing competing models of dorsal anterior cingulate

Vassena, E.; Deraeve, J.; Alexander, W. H.

10.1101/273706 — neuroscience — Posted on 2018-02-28

36 Ehmt1 forebrain haploinsufficiency leads to impaired memory, sensory gating and information processing

Davis, B. A.; David, F.; O'Regan, C.; Adam, M.; Harwood, A.; Crunelli, V.; Isles, A.

10.1101/257626 — neuroscience — Posted on 2018-02-28

37 Dazl regulates germ cell survival through a network of polyA proximal mRNA interactions

Zagore, L. L.; Sweet, T. J.; Hannigan, M. M.; Weyn-Vanhentenryck, S. M.; Zhang, C.; Licatalosi, D. D.

10.1101/273292 — molecular biology — Posted on 2018-02-28

38 A new function for Prokineticin 2: recruitment of SVZ-derived neuroblasts to the injured cortex in a mouse model of traumatic brain injury

Mundim, M. V.; Zamproni, L.; Pinto, A.; Galindo, L.; Xavier, A. M.; Glezer, I.; Porcionatto, M.

10.1101/273698 — neuroscience — Posted on 2018-02-28

39 RNASeq analysis identifies non-canonical role of STAT2 and IRF9 in the regulation of a STAT1-independent antiviral and immunoregulatory transcriptional program induced by IFNβ and TNFα

Mariani, M.; Dasmeh, P.; Fortin, A.; Kalamujic, M.; Caron, E.; Harrison, A. N.; Cervantes-Ortiz, S.; Mukawera, E.; Serohijos, A.; Grandvaux, N.

10.1101/273623 — immunology — Posted on 2018-02-28

40 Recruitment of Two Dyneins to an mRNA-Dependent Bicaudal D Transport Complex

Sladewski, T. E.; Billington, N.; Ali, M. Y.; Bookwalter, C. S.; Lu, H.; Krementsova, E. B.; Schroer, T. A.; Trybus, K. M.

10.1101/273755 — biophysics — Posted on 2018-02-28

41 MtMOT1.2 is responsible for molybdate supply to Medicago truncatula nodules

Gil-Diez, P.; Tejada-Jimenez, M.; Leon-Mediavilla, J.; Wen, J.; Mysore, K. S.; Imperial, J.; Gonzalez-Guerrero, M.

10.1101/272112 — plant biology — Posted on 2018-02-28

42 Assessment and refinement of sample preparation methods for deep and quantitative plant proteome profiling

Song, G.; Hsu, P. Y.; Walley, J. W.

10.1101/273656 — plant biology — Posted on 2018-02-28

43 How evolution draws trade-offs

Bourg, S.; Jacob, L.; Menu, F.; Rajon, E.

10.1101/169904 — evolutionary biology — Posted on 2018-02-28

44 The Parkinson’s Phenome: Traits Associated with Parkinson’s Disease in a Large and Deeply Phenotyped Cohort

Heilbron, K.; Noyce, A.; Fontanillas, P.; Alipanahi, B.; The 23andMe Research Team, ; Nalls, M.; Cannon, P.

10.1101/270934 — epidemiology — Posted on 2018-02-28

45 Blimp-1 mediates the temporal control of embryonic tube maturation

Ozturk-Colak, A.; Stephan-Otto Attolini, C.; Casanova, J.; Araujo, S. J.

10.1101/273151 — developmental biology — Posted on 2018-02-28

46 A Suv39H1-low chromatin state drives migratory cell populations in cervical cancers

Rodrigues, C.; Pattabiraman, C.; Mysore Narayana, S.; V Kumar, R.; Notani, D.; Varga-Weisz, P.; Krishna, S.

10.1101/241398 — cancer biology — Posted on 2018-02-28

47 In silico design of ligand triggered RNA switches

Findeiss, S.; Hammer, S.; Wolfinger, M. T. T.; Kuehnl, F.; Flamm, C.; Hofacker, I. L.

10.1101/245464 — bioinformatics — Posted on 2018-02-28

48 Control of mRNA decapping by autoinhibition

Paquette, D. R.; Tibble, R. W.; Daifuku, T. S.; Gross, J. D.

10.1101/266718 — biochemistry — Posted on 2018-02-28

49 Optimization and uncertainty analysis of ODE models using second order adjoint sensitivity analysis

Stapor, P.; Froehlich, F.; Hasenauer, J.

10.1101/272005 — systems biology — Posted on 2018-02-28

50 Stochastic satisficing account of confidence in uncertain value-based decisions

Hertz, U.; Bahrami, B.; Keramati, M.

10.1101/107532 — neuroscience — Posted on 2018-02-28

51 Enhancing resolution of natural methylome reprogramming behavior in plants

Sanchez, R.; Yang, X.; Kundariya, H.; Barreras, J. R.; Wamboldt, Y.; Mackenzie, S.

10.1101/252106 — genomics — Posted on 2018-02-28

52 Concurrent duplication of the Cid and Cenp-C genes in the Drosophila subgenus with signatures of subfunctionalization and male germline-biased expression

Teixeira, J. R.; Dias, G. B.; Svartman, M.; Ruiz, A.; Kuhn, G. C. S.

10.1101/134817 — genetics — Posted on 2018-02-28

53 The Mathematics of Descriptions in Descriptive Epidemiology

Ozonoff, D.; Pogel, A.

10.1101/273219 — epidemiology — Posted on 2018-02-28

54 In vivo optochemical control of cell contractility at single cell resolution by Ca2+ induced myosin activation

Kong, D.; Wolf, F.; Grosshans, J.

10.1101/255372 — developmental biology — Posted on 2018-02-28

55 Characterizing glutamate receptor genes of Rat having vertebrate nervous system and Arabidopsis thaliana a plant having equivalent nervous system based on chemical properties of amino acids and investigating evolutionary relationships between them.

Sengupta, A.; Pal Choudhury, P.

10.1101/273334 — systems biology — Posted on 2018-02-28

56 A Comprehensive Mathematical Model of Surface Electromyography and Force Generation

Petersen, E.; Rostalski, P.

10.1101/273458 — systems biology — Posted on 2018-02-28

57 Task errors contribute to implicit remapping in sensorimotor adaptation

Leow, L.-A.; Marinovic, W.; de rugy, A.; Carroll, T.

10.1101/263988 — neuroscience — Posted on 2018-02-28

58 Phase-amplitude coupling of neural oscillations can be effectively probed with concurrent TMS-EEG

Glim, S.; Okazaki, Y. O.; Nakagawa, Y.; Mizuno, Y.; Hanakawa, T.; Kitajo, K.

10.1101/273482 — neuroscience — Posted on 2018-02-28

59 Morphological Adaptations of Mitochondria in Spatially Restricted Axons Revealed by Cryo-Electron Tomography

Fischer, T. D.; Dash, P. K.; Liu, J.; Waxham, M. N.

10.1101/273052 — neuroscience — Posted on 2018-02-28

60 The hippocampal film-editor: sensitivity and specificity to event boundaries in continuous experience

Ben-Yakov, A.; Henson, R. N.

10.1101/273409 — neuroscience — Posted on 2018-02-28

61 Group IIA secreted phospholipase A2 in human serum kills commensal but not clinical Enterococcus faecium isolates

Paganelli, F. L.; Leavis, H. L.; He, S.; van Sorge, N. M.; Payre, C.; Lambeau, G.; Willems, R. J.; Rooijakkers, S. H.

10.1101/272617 — microbiology — Posted on 2018-02-28

62 GenBank 2 Sequin - a file converter preparing custom GenBank files for database submission

Lehwark, P.; Greiner, S.

10.1101/273441 — genomics — Posted on 2018-02-28

63 New perspectives on multilocus ancestry informativeness

Tal, O.; Tran, T. D.

10.1101/273466 — genetics — Posted on 2018-02-28

64 Theoretical foundation of the RelTime method for estimating divergence times from variable evolutionary rates

Tamura, K.; Tao, Q.; Kumar, S.

10.1101/180182 — evolutionary biology — Posted on 2018-02-28

65 Does Borrelia burgdorferi sensu lato facilitate the colonisation of marginal habitats by Ixodes ricinus? A correlative study in the Swiss Alps

Lemoine, M.; Cornetti, L.; Tschirren, B.

10.1101/273490 — ecology — Posted on 2018-02-28

66 Riding the Cell Jamming Boundary: Geometry, Topology, and Phase of Human Corneal Endothelium

Brookes, N. H.

10.1101/236406 — biophysics — Posted on 2018-02-28

67 Compartmentalized RNA catalysis in membrane - free coacervate protocells

Drobot, B.; Iglesias-Artola, J. M.; Le Vay, K.; Mayr, V.; Kar, M.; Kresying, M.; Mutschler, H.; Tang, T.-Y. D.

10.1101/273417 — biophysics — Posted on 2018-02-28

68 Genetic correlations among psychiatric and immune-related phenotypes based on genome-wide association data.

Tylee, D. S.; Sun, J.; Hess, J. L.; Tahir, M. A.; Sharma, E.; Malik, R.; Worrall, B. B.; Levine, A. J.; Martinson, J. J.; Nejenstev, S.; Speed, D.; Fischer, A.; Mick, E.; Walker, B. R.; Crawford, A.; Grant, S. F. A.; Polychronakos, C.; Bradfield, J. P.; Sleiman, P. M. A.; Hakonarson, H.; The METASTROKE Consortium of the International Str, ; The Netherlands Twin Registry, ; The neuroCHARGE Working Group, ; The Obsessive Compulsive and Tourette Syndrome Wor, ; Faraone, S. V.; Glatt, S. J.

10.1101/070730 — bioinformatics — Posted on 2018-02-28

69 Intrinsic limitations in mainstream methods of identifying network motifs in biology

Fodor, J.; Brand, M.; Stones, R. J.; Buckle, A. M.

10.1101/272401 — systems biology — Posted on 2018-02-28

70 Host factors influence the sex of nematodes parasitizing roots of Arabidopsis thaliana

Anjam, M. S.; Shah, S. J.; Matera, C.; Rozanska, E.; Sobczak, M.; Siddique, S.; Grundler, F.

10.1101/273391 — plant biology — Posted on 2018-02-28

71 Patterns of recurrence after curative-intent surgery for pancreas cancer reinforce the importance of locoregional control and adjuvant chemotherapy.

Munir, R.; Soreide, K.; Ravindran, R.; Powell, J. J.; Harrison, E.; Adair, A.; Wigmore, S.; Parks, R.; Garden, O. J.; Kirkpatrick, L.; Wall, L. R.; Christie, A.; Penman, I.; McAvoy, N.; Save, V.; Stockman, A.; Worrral, D.; Ireland, H.; Weir, G.; Masson, N.; Hay, C.; Gordon-Smith, J.; Mole, D. J.

10.1101/270884 — pathology — Posted on 2018-02-28

72 FALCON: a Functional Atlas of Language COmprehension Networks based on multiple task-induced activation mapping and graph analysis of intrinsic connectivity in 137 healthy right-handers

Labache, L.; Joliot, M.; Saracco, J.; Jobard, G.; Hesling, I.; Zago, L.; Mellet, E.; Petit, L.; Crivello, F.; Mazoyer, B.; Tzourio-Mazoyer, N.

10.1101/273227 — neuroscience — Posted on 2018-02-28

73 Prediction of Optimal Growth Temperature using only Genome Derived Features

Sauer, D.; Wang, D.-N.

10.1101/273094 — bioinformatics — Posted on 2018-02-28

74 Deep mutational analysis reveals functional trade-offs in the sequences of EGFR autophosphorylation sites

Cantor, A. J.; Shah, N. H.; Kuriyan, J.

10.1101/273516 — biochemistry — Posted on 2018-02-28

75 Ancestral diet leads to dynamic transgenerational plasticity for five generations in Drosophila melanogaster

Emborski, C.; Mikheyev, A.

10.1101/273144 — physiology — Posted on 2018-02-28

76 MicroRNA-449 sustains cilia-related networks in the absence of transcription factor TAp73

Wildung, M.; Esser, T. U.; Grausam, K. B.; Wiedwald, C.; Li, L.; Zylla, J. L. S.; Günther, A.-K.; Wienken, M.; Ercetin, E.; Bremmer, F.; Shomroni, O.; Andreas, S.; Zhao, H.; Lize, M.

10.1101/273375 — cell biology — Posted on 2018-02-28

77 Non-canonical HIF-1 stabilization is essential for intestinal tumorigenesis

Rohwer, N.; Jumpertz, S.; Erdem, M.; Egners, A.; Warzecha, K. T.; Fragoulis, A.; Kuehl, A. A.; Kramann, R.; Neuss, S.; Rudolph, I.; Endermann, T.; Zasada, C.; Apostolova, I.; Gerling, M.; Kempa, S.; Hughes, R.; Lewis, C. E.; Brenner, W.; Malinowski, M. B.; Stockmann, M.; Schomburg, L.; Faller, W.; Sansom, O. J.; Tacke, F.; Morkel, M.; Cramer, T.

10.1101/273045 — cancer biology — Posted on 2018-02-28

78 Multi-hierarchical Profiling the Structure-Activity Relationships of Engineered Nanomaterials at Nano-Bio Interfaces

Cai, X.; Dong, J.; Liu, J.; Zheng, H.; Kaweeteerawat, C.; Wang, F.; Ji, Z.; Li, R.

10.1101/273268 — pharmacology and toxicology — Posted on 2018-02-28

79 Discordant attributes of structural and functional connectivity in a two-layer multiplex network

Lim, S.; Radicchi, F.; van den Heuvel, M. P.; Sporns, O.

10.1101/273136 — neuroscience — Posted on 2018-02-28

80 Restoration of Kv7 channel mediated inhibition reduces cued-reinstatement of cocaine seeking

Parrilla-Carrero, J.; Buchta, W. C.; Goswamee, P.; Culver, O.; McKendrick, G.; Harlan, B.; Moutal, A.; Penrod, R.; Khanna, R.; Kalivas, P.; Riegel, A. C.

10.1101/272971 — neuroscience — Posted on 2018-02-28

81 The CRF-R1 regulation of VTA-GABAergic plasticity is suppressed by CB1 receptor inhibition following chronic exposure to alcohol

Harlan, B.; Becker, H.; Woodward, J.; Riegel, A. C.

10.1101/272997 — neuroscience — Posted on 2018-02-28

82 Neuroticism Impairs the Use of Reward Values for Decision-Making in Major Depression

Rupprechter, S.; Stankevicius, A.; Huys, Q.; Steele, D. J.; Series, P.

10.1101/273300 — neuroscience — Posted on 2018-02-28

83 Genetic recombination of poliovirus facilitates subversion of host barriers to infection

Acevedo, A.; Woodman, A.; Arnold, J. J.; Yeh, M. T.; Evans, D.; Cameron, C. E.; Andino, R.

10.1101/273060 — microbiology — Posted on 2018-02-28

84 Disruption in A-to-I editing levels affects C. elegans development more than a complete lack of editing

Ganem, N. S.; Ben-Asher, N.; Manning, A. C.; Deffit, S. N.; Washburn, M. C.; Wheeler, E. C.; Yeo, G. W.; Ben-Naim Zgayer, O.; Mantsur, E.; Hundley, H. A.; Lamm, A. T.

10.1101/273433 — genomics — Posted on 2018-02-28

85 Blimp-1 mediates the temporal control of embryonic tube maturation

Öztürk-Colak, A.; Stephan-Otto Attolini, C.; Casanova, J.; Araujo, S. J.

10.1101/273151 — developmental biology — Posted on 2018-02-28

86 A novel xenograft model reveals invasive mesenchymal transition and ineffective angiogenic response during the evolution of resistance to anti-angiogenic therapy

Jahangiri, A.; Chen, W.; Chandra, A.; Nguyen, A.; Weiss, J.; Wolf, K.; Lin, G.; Rick, J.; Sidorov, M.; Flanigan, P.; Yagnik, G.; Carbonell, W. S.; Kumar, S.; Aghi, M. K.

10.1101/272328 — cancer biology — Posted on 2018-02-28

87 Crossbrowse: A versatile genome browser for visualizing comparative experimental data

Shenker, S.; Lai, E.

10.1101/272880 — bioinformatics — Posted on 2018-02-28

88 High Numerical Aperture Epi-illumination Selective Plane Illumination Microscopy

Yang, B.; Wang, Y.; Feng, S.; Pessino, V.; Stuurman, N.; Huang, B.

10.1101/273359 — bioengineering — Posted on 2018-02-28

89 Post-decision wagering after perceptual judgments reveals bi-directional certainty readouts

Moreira, C. M.; Rollwage, M.; Kaduk, K.; Wilke, M.; Kagan, I.

10.1101/272872 — neuroscience — Posted on 2018-02-28

90 Performance of convolutional neural networks for identification of bacteria in 3D microscopy datasets

Hay, E. A.; Parthasarathy, R.

10.1101/273318 — microbiology — Posted on 2018-02-28

91 MicroRNAs as potential therapeutics to enhance chemosensitivity in advancedprostate cancer

Lin, H.-M.; Nikolic, I.; Yang, J.; Castillo, L.; Deng, N.; Chan, C.-L.; Yeung, N. K.; Dodson, E.; Elsworth, B.; Spielman, C.; Lee, B.; Boyer, Z.; Simpson, K.; Daly, R. J.; Horvath, L. G.; Swarbrick, A.

10.1101/273284 — cancer biology — Posted on 2018-02-28

92 Femtomolar and selective dopamine detection by a gold nanoparticle enhanced surface plasmon resonance aptasensor

Cao, Y.; McDermott, M. T.

10.1101/273078 — biochemistry — Posted on 2018-02-28

93 Morphological Adaptations of Mitochondria in Spatially Restricted Axons Revealed by Cryo-Electron Tomography

Fischer, T. D.; Dash, P. K.; Liu, J.; Waxham, M. N.

10.1101/273052 — neuroscience — Posted on 2018-02-28

94 Comprehensive Genetic Testing for Female and Male Infertility Using Next Generation Sequencing

Patel, B.; Parets, S.; Akana, M.; Kellogg, G.; Jansen, M.; Chang, C.; Cai, Y.; Fox, R.; Niknazar, M.; Shraga, R.; Hunter, C.; Pollock, A.; Wisotzkey, R.; Jaremko, M.; Bisignano, A.; Puig, O.

10.1101/272419 — genomics — Posted on 2018-02-28

95 Clonal expansion of mitochondrial DNA deletions is a private mechanism of ageing in long-lived animals

Lakshmanan, L. N.; Yee, Z.; Ng, L. F.; Gunawan, R.; Halliwell, B.; Gruber, J.

10.1101/273326 — genetics — Posted on 2018-02-28

96 Adaptive Reduction of Male Gamete Number in a Selfing Species

Tsuchimatsu, T.; Kakui, H.; Yamazaki, M.; Marona, C.; Tsutsui, H.; Hedhly, A.; Meng, D.; Sato, Y.; Stadler, T.; Grossniklaus, U.; Kanaoka, M. M.; Lenhard, M.; Nordborg, M.; Shimizu, K. K.

10.1101/272757 — evolutionary biology — Posted on 2018-02-28

97 The yeast core spliceosome maintains genome integrity through R-loop prevention and alpha-tubulin expression

Tam, A. S.; Mathew, V.; Sihota, T. S.; Zhang, A.; Stirling, P. C.

10.1101/272807 — cell biology — Posted on 2018-02-28

98 Plasma redox imbalance caused by albumin oxidation promotes lung-predominant NETosis and pulmonary cancer metastasis

Inoue, M.; Enomoto, M.; Koike, Y.; Di Grappa, M. A.; Zhao, X.; Yip, K.; Huang, S. H.; Waldron, J. N.; Ikura, M.; Liu, F.-F.; Bratman, S. V.

10.1101/273037 — cancer biology — Posted on 2018-02-28

99 Network mechanisms underlying the role of oscillations in cognitive tasks

Schmidt, H.; Avitabile, D.; Montbrio, E.; Roxin, A.

10.1101/271973 — neuroscience — Posted on 2018-02-27

100 Temporal Multivariate Pattern Analysis (tMVPA): a single trial approach exploring the temporal dynamics of the BOLD signal

Vizioli, L.; Bratch, A.; Lao, J.; Ugurbil, K.; Muckli, L.; Yacoub, E.

10.1101/273110 — neuroscience — Posted on 2018-02-27

101 Most calbindin-immunoreactive neurons, but few calretinin-immunoreactive neurons, express the m1 acetylcholine receptor in the middle temporal visual area of the macaque monkey

Coppola, J. J.; Disney, A. A.

10.1101/271924 — neuroscience — Posted on 2018-02-27

102 Characterising RAG1 and RAG2 with predictive genomics

Lawless, D.; Walter, J. E.; Anwar, R.; Savic, S.

10.1101/272609 — genomics — Posted on 2018-02-27

103 Capturing the onset of PRC2-mediated repressive domain formation

Oksuz, O.; Narendra, V.; Lee, C.-H.; Descostes, N.; LeRoy, G.; Raviram, R.; Blumenberg, L.; Karch, K.; Rocha, P. R.; Garcia, B. A.; Skok, J. A.; Reinberg, D.

10.1101/272989 — genomics — Posted on 2018-02-27

104 Prediction of Optimal Growth Temperature using only Genome Derived Features

Sauer, D.; Wang, D.-N.

10.1101/273094 — bioinformatics — Posted on 2018-02-27

105 Reproducible big data science: A case study in continuous FAIRness

Madduri, R. K.; Chard, K.; D'Arcy, M.; Jung, S. C.; Rodriguez, A.; Sulakhe, D.; Deutsch, E. W.; Funk, C.; Heavner, B.; Richards, M.; Shannon, P.; Dinov, I.; Glusman, G.; Price, N.; Van Horn, J. D.; Kesselman, C.; Toga, A. W.; Foster, I.

10.1101/268755 — bioinformatics — Posted on 2018-02-27

106 Variable training but not sleep improves consolidation of motor adaptation

Thuerer, B.; Weber, F.; Born, J.; Stein, T.

10.1101/259671 — neuroscience — Posted on 2018-02-27

107 Natural selection on plasticity of thermal traits in a highly seasonal environment

Bacigalupe, L. D.; Barria, A. M.; Gonzalez-Mendez, A.; Ruiz-Aravena, M.; Gaitan-Espitia, J. D.; Trinder, M.; Sinervo, B.

10.1101/191825 — evolutionary biology — Posted on 2018-02-27

108 cisTEM: User-friendly software for single-particle image processing

Grant, T.; Rohou, A.; Grigorieff, N.

10.1101/257618 — biophysics — Posted on 2018-02-27

109 Noise-induced bistability in the quasineutral coexistence of viral RNA under different replication modes

Alarcon, T.; Sardanyes, J.; Arderiu, A.; Elena, S.

10.1101/272906 — systems biology — Posted on 2018-02-27

110 Rare Variant Pathogenicity Triage and Inclusion of Synonymous Variants Improves Analysis of Disease Associations

Dershem, R.; Metpally, R. P. R.; Jeffreys, K.; Krishnamurthy, S.; Carey, D. J.; Hershfinkel, M.; Robishaw, J. D.; Breitwieser, G. E.

10.1101/272955 — genetics — Posted on 2018-02-27

111 The first set of universal nuclear protein-coding loci markers for avian phylogenetic and population genetic studies

Liu, Y.; Liu, S.; Yeh, C.-F.; Zhang, N.; Chen, G.; Que, P.; Dong, L.; Li, S.-H.

10.1101/272732 — evolutionary biology — Posted on 2018-02-27

112 Host-parasite coevolution can promote the evolution of seed banking as a bet-hedging strategy

Verin, M.; Tellier, A.

10.1101/273003 — evolutionary biology — Posted on 2018-02-27

113 Thermal niche evolution across replicated Anolis lizard adaptive radiations

Gunderson, A. R.; Mahler, D. L.; Leal, M.

10.1101/069294 — evolutionary biology — Posted on 2018-02-27

114 Effect sizes of somatic mutations in cancer

Cannataro, V. L.; Gaffney, S. G.; Townsend, J. P.

10.1101/229724 — cancer biology — Posted on 2018-02-27

115 Integrated time course omics analysis distinguishes immediate therapeutic response from acquired resistance.

Stein-O'Brien, G.; Kagohara, L. T.; Li, S.; Thakar, M.; Ranaweera, R.; Ozawa, H.; Cheng, H.; Considine, M.; Schmitz, S.; Favorov, A.; Danilova, L.; Califano, J. A.; Izumchenko, E.; Gaykalova, D. A.; Chung, C. H.; Fertig, E. J.

10.1101/136564 — systems biology — Posted on 2018-02-27

116 Delegating sex: differential gene expression in stolonizing syllids uncovers the hormonal control of reproduction in Annelida

Alvarez-Campos, P.; Kenny, N.; Verdes, A.; Fernandez, R. M.; Novo, M.; Giribet, G.; Riesgo, A.

10.1101/271783 — molecular biology — Posted on 2018-02-27

117 Specific enrichment of hyperthermophilic electroactive Archaea from deep-sea hydrothermal vent on electrically conductive support

Pillot, G.; Frouin, E.; Pasero, E.; Godfroy, A.; Combet-Blanc, Y.; Davidson, S.; Liebgott, P.-P.

10.1101/272039 — microbiology — Posted on 2018-02-27

118 Influenza A virus environmental persistence is driven by the hemagglutinin and the neuraminidase

Labadie, T.; Batejat, C.; Manuguerra, J.-C.; Leclercq, I.

10.1101/268722 — microbiology — Posted on 2018-02-27

119 Significant shared heritability underlies suicide attempt and clinically predicted probability of attempting suicide

Ruderfer, D. M.; Walsh, C. G.; Aguirre, M. W.; Tanigawa, Y.; Ribeiro, J. D.; Franklin, J. C.; Rivas, M. A.

10.1101/266411 — genomics — Posted on 2018-02-27

120 Genomic imprinting mediates dosage compensation in a young plant XY system

Muyle, A.; Zemp, N.; Fruchard, C.; Cegan, R.; Vrana, J.; Deschamps, C.; Tavares, R.; Picard, F.; Hobza, R.; Widmer, A.; Marais, G.

10.1101/179044 — evolutionary biology — Posted on 2018-02-27

121 Revealing mechanisms of infectious disease transmission through empirical contact networks

Sah, P.; Otterstatter, M.; Leu, S. T.; Leviyang, S.; Bansal, S.

10.1101/169573 — epidemiology — Posted on 2018-02-27

122 Mitochondrial ATP synthase dimers spontaneously self-associate driven by a long-ranged membrane-induced force

Anselmi, C.; Davies, K. M.; Faraldo-Gomez, J. D.

10.1101/272146 — biophysics — Posted on 2018-02-27

123 babette: BEAUti 2, BEAST2 and Tracer for R

Bilderbeek, R. J. C.; Etienne, R. S.

10.1101/271866 — bioinformatics — Posted on 2018-02-27

124 FALCON: a method to infer metagenomic composition of ancient DNA

Pratas, D.; Pinho, A. J.; Silva, R. M.; Rodrigues, J. M. O. S.; Hosseini, M.; Caetano, T.; Ferreira, P. J. S. G.

10.1101/267179 — bioinformatics — Posted on 2018-02-27

125 Converging Evidence from Electrocorticography and BOLD fMRI for a Sharp Functional Boundary in Superior Temporal Gyrus Related to Multisensory Speech Processing

Beauchamp, M.; Ozker, M.

10.1101/272823 — neuroscience — Posted on 2018-02-27

126 Altered neocortical gene expression, brain overgrowth and functional over-connectivity in Chd8 haploinsufficient mice

Suetterlin, P.; Hurley, S.; Mohan, C.; Riegman, K. L. H.; Pagani, M.; Caruso, A.; Ellegood, J.; Galbusera, A.; Crespo-Enriquez, I.; Michetti, C.; Yee, Y.; Ellingford, R.; Brock, O.; Delogu, A.; Francis-West, P.; Lerch, J. P.; Scattoni, M. L.; Gozzi, A.; Fernandes, C.; Basson, A.

10.1101/143552 — neuroscience — Posted on 2018-02-27

127 Thalamostriatal Interactions in Human Reversal Learning

Bell, T.; Langdon, A.; Lindner, M.; Lloyd, W.; Christakou, A.

10.1101/246371 — neuroscience — Posted on 2018-02-27

128 Pervasive transcription-dependent chromatin remodeling influences the replication initiation program

Soudet, J.; Kaur, J.; Stutz, F.

10.1101/272666 — molecular biology — Posted on 2018-02-27

129 A catalog of microbial genes from the bovine rumen reveals the determinants of herbivory

Li, J.; Zhong, H.; Ramayo-Caldas, Y.; Terrapon, N.; Lombard, V.; Potocki-Veronese, G.; Estelle-Fabrellas, J.; Popova, M.; Yang, Z.; Zhang, H.; Li, F.; Tang, S.; Chen, W.; Chen, B.; Li, J.; Guo, J.; Martin, C.; Maguin, E.; Xu, X.; Yang, H.; Wang, J.; Madsen, L.; Kristiansen, K.; Henrissat, B.; Ehrlich, S. D.; Morgavi, D. P.

10.1101/272690 — microbiology — Posted on 2018-02-27

130 Microbiomes of North American Triatominae: the grounds for Chagas disease epidemiology

Rodriguez-Ruano, S. M.; Skochova, V.; Rego, R. O. M.; Schmidt, J. O.; Roachell, W.; Hypsa, V.; Novakova, E.

10.1101/269845 — microbiology — Posted on 2018-02-27

131 Live Zika virus chimeric vaccine candidate based on a yellow fever 17-D attenuated backbone

Touret, F.; Gilles, M.; Klitting, R.; Aubry, F.; de Lamballerie, X.; Nougairede, A.

10.1101/272625 — microbiology — Posted on 2018-02-27

132 High throughput characterization of genetic effects on DNA:protein binding and gene transcription

Kalita, C. A.; Brown, C. D.; Freiman, A.; Isherwood, J.; Wen, X.; Pique-Regi, R.; Luca, F.

10.1101/270991 — genetics — Posted on 2018-02-27

133 Evolution at two time frames: polymorphisms from an ancient singular divergence event fuel contemporary parallel evolution

Van Belleghem, S.; Vangestel, C.; De Wolf, K.; De Corte, Z.; Moest, M.; Rastas, P.; De Meester, L.; Hendrickx, F.

10.1101/255554 — evolutionary biology — Posted on 2018-02-27

134 Big data analysis of mitochondrial DNA substitution models: A regression approach elucidating the effects of codon position and neighboring nucleotides

Levinstein Hallak, K.; Tzur, S.; Rosset, S.

10.1101/272922 — evolutionary biology — Posted on 2018-02-27

135 Verified the effectiveness of AsCpf1 system in a variety of vertebrate species

Li, Z.; Shi, Z.; Fan, N.; Chen, Y.; Guo, J.; Wu, J.; Song, H.; Chu, S.; Mo, K.; Zhao, B.; Ouyang, Z.; Tian, D.; Zhao, S.; Zhu, J.; Chen, J.; Chen, Y.; Lai, L.; Pei, D.

10.1101/272716 — developmental biology — Posted on 2018-02-27

136 NF1 deficiency correlates with estrogen receptor signaling and diminished survival in breast cancer

Dischinger, P. S.; Tovar, E. A.; Essenburg, C. J.; Madaj, Z. B.; Gardner, E. E.; Callaghan, M.; Turner, A. N.; Challa, A. K.; Kempston, T.; Eagleson, B.; Kesterson, R. A.; Bronson, R. T.; Bowman, M. J.; Graveel, C. R.; Steensma, M. R.

10.1101/272815 — cancer biology — Posted on 2018-02-27

137 Aberrant resting-state functional brain networks in dyslexia: Symbolic mutual information analysis of neuromagnetic signals

Dimitriadis, S. I.; Simos, P. G.; Fletcher, J. M.; Papanicolaou, A.

10.1101/272567 — neuroscience — Posted on 2018-02-27

138 Variations in neuromodulatory chemical signatures define compartments in macaque cortex

Ward, N. J.; Zinke, W.; Coppola, J. J.; Disney, A. A.

10.1101/272849 — neuroscience — Posted on 2018-02-27

139 Improvement of ADHD symptoms in School Age Children and Adolescents with Autism via a Digital Smartglasses-based Socio-emotional Coaching Aid

Vahabzadeh, A.; Keshav, N. U.; Salisbury, J. P.; Sahin, N. T.

10.1101/165514 — neuroscience — Posted on 2018-02-27

140 Optimized real-time qPCR assays for detecting and quantifying the Fusarium and Microdochium species responsible for wheat head blight, as defined by MIQE guidelines

Elbelt, S.; Siou, D.; Gelisse, S.; Cruaud, C.; Lannou, C.; Lebrun, M.-H.; Laval, V.

10.1101/272534 — molecular biology — Posted on 2018-02-27

141 In vivo CRISPR-Cas gene editing with no detectable genome-wide off-target mutations

Akcakaya, P.; Bobbin, M. L.; Guo, J. A.; Lopez, J. M.; Clement, M. K.; Garcia, S. P.; Fellows, M. D.; Porritt, M. J.; Firth, M. A.; Carreras, A.; Baccega, T.; Seeliger, F.; Bjursell, M.; Tsai, S. Q.; Nguyen, N. T.; Nitsch, R.; Mayr, L.; Pinello, L.; Bohlooly-Y, M.; Aryee, M. J.; Maresca, M.; Joung, J. K.

10.1101/272724 — molecular biology — Posted on 2018-02-27

142 Pervasive epistasis modulates neurodevelopmental defects of the autism-associated 16p11.2 deletion

Iyer, J.; Singh, M. D.; Jensen, M.; Patel, P.; Pizzo, L.; Huber, E.; Koerselman, H.; Weiner, A. T.; Lepanto, P.; Vadodaria, K.; Kubina, A.; Wang, Q.; Talbert, A.; Yennawar, S.; Badano, J.; Manak, J. R.; Rolls, M. M.; Krishnan, A.; Girirajan, S.

10.1101/185355 — genomics — Posted on 2018-02-27

143 The dynamics of preferential host switching: host phylogeny as a key predictor of parasite prevalence and distribution

Engelstaedter, J.; Fortuna, N. Z.

10.1101/209254 — evolutionary biology — Posted on 2018-02-27

144 A frailty index for UK Biobank participants

Williams, D. M.; Jylhava, J.; Pedersen, N. L.; Hagg, S.

10.1101/233692 — epidemiology — Posted on 2018-02-27

145 Niche separation increases with genetic distance among bloom-forming cyanobacteria

Tromas, N.; Taranu, Z. E.; Martin, B. D.; Willis, A.; Fortin, N.; Greer, C. W.; Shapiro, B. J.

10.1101/226860 — ecology — Posted on 2018-02-27

146 Macropinocytosis overcomes directional bias due to hydraulic resistance to enhance space exploration by dendritic cells

Moreau, H. D.; Blanch-Mercader, C.; Attia, R.; Alraies, Z.; Maurin, M.; Bousso, P.; Joanny, J.-F.; Voituriez, R.; Piel, M.; Lennon-Dumenil, A.-M.

10.1101/272682 — cell biology — Posted on 2018-02-27

147 How well do force fields capture the strength of salt bridges in proteins?

Ahmed, M. C.; Papaleo, E.; Lindorff-Larsen, K.

10.1101/272799 — biophysics — Posted on 2018-02-27

148 TOGGLe, a flexible framework for easily building complex workflows and performing robust large-scale NGS analyses

Tranchant-Dubreuil, C.; Ravel, S.; Monat, C.; Sarah, G.; Diallo, A.; Helou, L.; Dereeper, A.; Tando, N.; Orjuela-Bouniol, J.; Sabot, F.

10.1101/245480 — bioinformatics — Posted on 2018-02-27

149 Salt-bridge Dynamics in Intrinsically Disordered Proteins: A trade-off between electrostatic interactions and structural flexibility

Basu, S.; Biswas, P.

10.1101/220392 — bioinformatics — Posted on 2018-02-27

150 MACPET: Model-based Analysis for ChIA-PET

Vardaxis, I.; Drablos, F.; Rye, M. B.; Lindqvist, B. H.

10.1101/272559 — bioinformatics — Posted on 2018-02-27

151 Predicting clinically promising therapeutic hypotheses using tensor factorization

Yao, J.; Hurle, M. R.; Nelson, M. R.; Agarwal, P.

10.1101/272740 — bioinformatics — Posted on 2018-02-27

152 ChIPdig: a comprehensive user-friendly tool for mining multi-sample ChIP-seq data

Esse, R.; Grishok, A.

10.1101/220079 — bioinformatics — Posted on 2018-02-27

153 Task errors contribute to implicit remapping in sensorimotor adaptation

Leow, L.-A.; Marinovic, W.; de rugy, A.; Carroll, T.

10.1101/263988 — neuroscience — Posted on 2018-02-27

154 Group IIA secreted phospholipase A2 in human serum kills commensal but not clinical Enterococcus faecium isolates

Paganelli, F. L.; Leavis, H. L.; He, S.; van Sorge, N. M.; Payre, C.; Gerard, G.; Willems, R. J.; Rooijakkers, S. H.

10.1101/272617 — microbiology — Posted on 2018-02-27

155 Structural variation detection by proximity ligation from FFPE tumor tissue

Troll, C.; Putnam, N. H.; Hartley, P. D.; Rice, B.; Blanchette, M.; Siddiqui, S.; Ganbat, J.-O.; Powers, M. P.; Kunder, C. A.; Bustamante, C. D.; Zehnder, J. L.; Green, R. E.; Costa, H. A.

10.1101/266023 — genomics — Posted on 2018-02-27

156 A High-Resolution Genetic Map for the Laboratory Rat

Littrell, J.; Tsaih, S.-W.; Baud, A.; Rastas, P. M. A.; Solberg-Woods, L.; Flister, M.

10.1101/268227 — genetics — Posted on 2018-02-27

157 Improving the accuracy of two-sample summary data Mendelian randomization: moving beyond the NOME assumption

Bowden, J.; Del Greco M, F.; Minelli, C.; Lawlor, D.; Zhao, Q.; Sheehan, N.; Thompson, J.; Davey Smith, G.

10.1101/159442 — epidemiology — Posted on 2018-02-27

158 Characterization of convergent thickening, a major convergence force producing morphogenic movement in amphibians

Shook, D. R.; Wen, J.; Rolo, A.; Francica, B.; Dobins, D.; Skoglund, P.; DeSimone, D.; Winklbauer, R.; Keller, R.

10.1101/270892 — developmental biology — Posted on 2018-02-27

159 OMEGA: a software tool for the management, analysis, and dissemination of intracellular trafficking data that incorporates motion type classification and quality control

Rigano, A.; Galli, V.; Clark, J. M.; Pereira, L. E.; Grossi, L.; Luban, J.; Giulietti, R.; Leidi, T.; Hunter, E.; Valle, M.; Sbalzarini, I. F.; Strambio-De-Castillia, C.

10.1101/251850 — bioinformatics — Posted on 2018-02-27

160 Human axial progenitors generate trunk neural crest cells

Frith, T. J. R.; Granata, I.; Stout, E.; Wind, M.; Thompson, O.; Neumann, K.; Stavish, D.; Heath, P. R.; Hackland, J. O. S.; Anastassiadis, K.; Gouti, M.; Briscoe, J.; Wilson, V.; Guarracino, M. R.; Andrews, P. W.; Tsakiridis, A.

10.1101/272591 — developmental biology — Posted on 2018-02-27

161 Combining multiple functional annotation tools increases coverage of metabolic annotation

Griesemer, M.; Kimbrel, J. A.; Zhou, C. E.; Navid, A.; D'haeseleer, P.

10.1101/160887 — bioinformatics — Posted on 2018-02-27

162 p53 deletion rescues apoptosis and microcephaly in a Kif20b mouse mutant

Little, J. N.; Dwyer, N. D.

10.1101/272393 — developmental biology — Posted on 2018-02-27

163 Large, long range tensile forces drive convergence during Xenopus blastopore closure and body axis elongation

Shook, D. R.; Keller, R.; Davidson, L.; Kasprowicz, E. M.

10.1101/126201 — biophysics — Posted on 2018-02-27

164 Lineage: Visualizing Multivariate Clinical Data in Genealogy Graphs

Nobre, C.; Gehlenborg, N.; Coon, H.; Lex, A.

10.1101/128579 — bioinformatics — Posted on 2018-02-27

165 Optimization and uncertainty analysis of ODE models using second order adjoint sensitivity analysis

Stapor, P.; Froehlich, F.; Hasenauer, J.

10.1101/272005 — systems biology — Posted on 2018-02-27

166 A Lotus japonicus E3 ligase interacts with the Nod factor receptor 5 and positively regulates nodulation

Tsikou, D.; Ramirez, E. E.; Psarrakou, I. S.; Wong, J. E.; Jensen, D. B.; Isono, E.; Radutoiu, S.; Papadopoulou, K. K.

10.1101/269506 — plant biology — Posted on 2018-02-27

167 End-to-end deep image reconstruction from human brain activity

Shen, G.; Dwivedi, K.; Majima, K.; Horikawa, T.; Kamitani, Y.

10.1101/272518 — neuroscience — Posted on 2018-02-27

168 A synaptic threshold mechanism for computing escape decisions

Evans, D. A.; Stempel, V.; Vale, R.; Ruehle, S.; Lefler, Y.; Branco, T.

10.1101/272492 — neuroscience — Posted on 2018-02-27

169 The thalamus regulates retinoic acid signaling and development of parvalbumin interneurons in postnatal mouse prefrontal cortex

Larsen, R.; Proue, A.; Christiansen, M.; Nakagawa, Y.

10.1101/272427 — neuroscience — Posted on 2018-02-27

170 The tumor suppressor FBW7 and the vitamin D receptor are mutual cofactors.

White, J. H.; Salehi-Tabar, R.; Memari, B.; Wong, H.; Rochel, N.

10.1101/272500 — molecular biology — Posted on 2018-02-27

171 The t haplotype, a selfish genetic element, manipulates migration propensity in free-living wild house mice Mus musculus domesticus

Runge, J.-N.; Lindholm, A. K.

10.1101/271247 — evolutionary biology — Posted on 2018-02-27

172 HDGF supports anti-apoptosis and pro-fibrosis in pancreatic stellate cells of pancreatic cancer

Chen, Y.-T.; Li, C.-F.; Wang, T.-W.; Chang, T.-H.; Hsu, T.-P.; Chi, J.-Y.; Hsiao, Y.-W.; Wang, J.-M.

10.1101/272542 — cancer biology — Posted on 2018-02-27

173 Learning common and specific patterns from data of multiple interrelated biological scenarios with matrix factorization

Zhang, L.; Zhang, S.

10.1101/272443 — bioinformatics — Posted on 2018-02-27

174 VideoTagger: User-Friendly Software for Annotating Video Experiments of Any Duration

Rennert, P.; Mac Aodha, O.; Piper, M.; Brostow, G.

10.1101/272468 — animal behavior and cognition — Posted on 2018-02-27

175 COMPUTING SIGNAL TRANSDUCTION IN SIGNALING NETWORKS MODELED AS BOOLEAN NETWORKS, PETRI NETS AND HYPERGRAPHS

Sordo Vieira, ; Vera-Licona, P.

10.1101/272344 — systems biology — Posted on 2018-02-26

176 Ratiometric assays of autophagic flux in zebrafish for analysis of familial Alzheimer’s disease-like mutations

Jiang, H.; Newman, M.; Ratnayake, D.; Lardelli, M.

10.1101/272351 — molecular biology — Posted on 2018-02-26

177 Estimating numbers of fluorescent molecules in single cells by analysing fluctuations in photobleaching

Bakker, E.; Swain, P. S.

10.1101/272310 — systems biology — Posted on 2018-02-26

178 Active degradation of a regulator controls coordination of downstream genes

Rossi, N. A.; Mora, T.; Walczak, A. M.; Dunlop, M. J.

10.1101/272120 — systems biology — Posted on 2018-02-26

179 Human primary astrocytes increase basal fatty acid oxidation following recurrent low glucose to maintain intracellular nucleotide levels

Weightman Potter, P. G.; Vlachaki Walker, J. M.; Robb, J. L.; Chilton, J. K.; Williamson, R.; Randall, A. D.; Ellacott, K.; Beall, C.

10.1101/271981 — neuroscience — Posted on 2018-02-26

180 The Impact of Spatial Normalization for Functional Magnetic Resonance Imaging Data Analyses Revisited

Smith, J. F.; Hur, J.; Kaplan, C. M.; Shackman, A. J.

10.1101/272302 — neuroscience — Posted on 2018-02-26

181 An eicosanoid protects from statin-induced myopathic changes in primary human cells

Grunwald, S.; Popp, O.; Haafke, S.; Jedraszczak, N.; Grieben, U.; Saar, K.; Patone, G.; Kress, W.; Steinhagen-Thiessen, E.; Dittmar, G.; Spuler, S.

10.1101/271932 — molecular biology — Posted on 2018-02-26

182 Delegating Sex: differential gene expression in stolonizing syllids uncover the hormonal control of reproduction in Annelida

Alvarez-Campos, P.; Kenny, N.; Verdes, A.; Fernandez, R. M.; Novo, M.; Giribet, G.; Riesgo, A.

10.1101/271783 — molecular biology — Posted on 2018-02-26

183 A novel environmental DNA (eDNA) sampling method for aye-ayes from their feeding traces

Aylward, M. L.; Johnson, S. E.; Sullivan, A. P.; Perry, G. H.; Louis, E. E.

10.1101/272153 — molecular biology — Posted on 2018-02-26

184 α-proteobacterial RNA degradosomes assemble liquid-liquid phase separated RNP bodies

Al-Husini, N.; Tomares, D. T.; Childers, W. S.; Schrader, J.

10.1101/272286 — molecular biology — Posted on 2018-02-26

185 Improved sgRNA design in bacteria via genome-wide activity profiling

Guo, J.; Wang, T.; Guan, C.; Liu, B.; Luo, C.; Xie, Z.; Zhang, C.; Xing, X.-H.

10.1101/272377 — microbiology — Posted on 2018-02-26

186 Specific enrichment of hyperthermophilic electroactive Archaea from deep-sea hydrothermal vent on electrically conductive support

Guillaume, P.; Frouin, E.; Pasero, E.; Godfroy, A.; Combet-Blanc, Y.; Davidson, S.; Liebgott, P.-P.

10.1101/272039 — microbiology — Posted on 2018-02-26

187 CONSTRUCTION OF WHOLE GENOMES FROM SCAFFOLDS USING SINGLE CELL STRAND-SEQ DATA

Hills, M.; Falconer, E.; O'Neil, K.; Sanders, A.; Howe, K.; Guryev, V.; Lansdorp, P. M.

10.1101/271510 — genomics — Posted on 2018-02-26

188 Ribo-tag translatomic profiling of Drosophila oenocyte reveals down-regulation of peroxisome and mitochondria biogenesis under aging and oxidative stress

Huang, K.; Chen, W.; Bai, H.

10.1101/272179 — genomics — Posted on 2018-02-26

189 Subset-based genomic prediction provides insights into the genetic architecture of free amino acid levels in dry Arabidopsis thaliana seeds

Bird, K. A.; Turner, S. D.; Beissinger, T. M.; Angelovici, R.

10.1101/272047 — genetics — Posted on 2018-02-26

190 Association of Arg389Gly β1-adrenergic receptor polymorphism with effective dose of β blocker in congestive heart failure among Chinese Han population

Gu, R.; Shen, Y.; Liu, J.; Qiao, S.; Xu, B.; Wang, L.

10.1101/272013 — genetics — Posted on 2018-02-26

191 Comparative demography elucidates the longevity of parasitic and symbiotic relationships.

Hecht, L. B. B.; Thompson, P. C.; Rosenthal, B. M.

10.1101/271965 — evolutionary biology — Posted on 2018-02-26

192 Sex-specific additive genetic variances and correlations for fitness in a song sparrow (Melospiza melodia) population subject to natural immigration and inbreeding

Wolak, M. E.; Arcese, P.; Keller, L. F.; Reid, J. M.

10.1101/272138 — evolutionary biology — Posted on 2018-02-26

193 Oxygen diffusion in ellipsoidal tumor spheroids

Grimes, D. R.; Currell, F. J.

10.1101/271890 — cancer biology — Posted on 2018-02-26

194 Hamiltonian distributed chaos in DNA

Bershadskii, A.

10.1101/272054 — biophysics — Posted on 2018-02-26

195 SMuRF: a novel tool to identify genomic regions enriched for somatic point mutations

Guilhamon, P.; Lupien, M.

10.1101/271957 — bioinformatics — Posted on 2018-02-26

196 Rotational 3D mechanogenomic Turing patterns of human colon Caco-2 cells during differentiation

Zheng, G.; Kalinin, A. A.; Dinov, I. D.; Meixner, W.; Zhu, S.; Wiley, J. W.

10.1101/272096 — bioinformatics — Posted on 2018-02-26

197 GenFam: A new web application for gene family-based classification and functional enrichment analysis of plant genomes

Bedre, R.; Mandadi, K.

10.1101/272187 — bioinformatics — Posted on 2018-02-26

198 ProtaBank: A repository for protein design and engineering data

Wang, C. Y.; Chang, P. M.; Ary, M. L.; Allen, B. D.; Chica, R. A.; Mayo, S. L.; Olafson, B. D.

10.1101/272211 — bioinformatics — Posted on 2018-02-26

199 A prize-collecting Steiner tree application for signature selection to stratify diffuse large B-cell lymphoma subtypes

Akhmedov, M.; Galbusera, L.; Montemanni, R.; Bertoni, F.; Kwee, I.

10.1101/272294 — bioinformatics — Posted on 2018-02-26

200 VirTect: a computational method for detecting virus species from RNA-Seq and its application in head and neck squamous cell carcinoma

Khan, A.; Liu, Q.; Chen, X.; Zeng, Y.; Stucky, A.; Sedghizadeh, P. P.; Adelpour, D.; Zhang, X.; Wang, K.; Zhong, J. F.

10.1101/272278 — bioinformatics — Posted on 2018-02-26

201 Structural basis of human 5,10-methylenetetrahydrofolate reductase (MTHFR) regulation by phosphorylation and S-adenosylmethionine inhibition

Froese, D. S.; Kopec, J.; Rembeza, E.; Bezerra, G. A.; Oberholzer, A.; Suormala, T.; Lutz, S.; Chalk, R.; Borkowska, O.; Baumgartner, M.; Yue, W.

10.1101/271593 — biochemistry — Posted on 2018-02-26

202 Monkeys predict trajectories of virtual prey using basic variables from Newtonian physics.

Yoo, S. B. M.; Piantadosi, S. T.; Hayden, B. Y.

10.1101/272260 — animal behavior and cognition — Posted on 2018-02-26

203 Development of a novel protein identification approach to define mitochondrial proteomic signatures in glioblastoma oncogenesis: T98G vs U87MG cell lines model.

Gomez-Caudillo, L.; Martinez-Batallar, A.; Ortega-Lozano, A.; Fernandez-Coto, D.; Rosas-Vargas, H.; Minauro, F.; Encarnacion-Guevara, S.

10.1101/270942 — systems biology — Posted on 2018-02-26

204 Chemogenetic Manipulations of Ventral Tegmental Area Dopamine Neurons Reveal Multifaceted Roles in Cocaine Abuse

Mahler, S. V.; Brodnik, Z. D.; Cox, B. M.; Buchta, W. C.; Bentzley, B. S.; Cope, Z. A.; Lin, E. C.; Riedy, M. D.; Scofield, M. D.; Messinger, J.; Riegel, A. C.; Espana, R. A.; Aston-Jones, G.

10.1101/246595 — neuroscience — Posted on 2018-02-26

205 Circular RNA expression and regulatory network prediction in posterior cingulate astrocytes in elderly subjects

Sekar, S.; Cuyugan, L.; Adkins, J.; Geiger, P.; Liang, W.

10.1101/268888 — neuroscience — Posted on 2018-02-26

206 A Signature of Passivity? An Explorative Study of the N3 Event-Related Potential Component in Passive Oddball Tasks

Kotchoubey, B.; Pavlov, Y. G.

10.1101/271502 — neuroscience — Posted on 2018-02-26

207 Conserved Methyltransferase Spb1 Targets mRNAs for Regulated Modification with 2′-O-Methyl Ribose

Bartoli, K. M.; Schaening, C.; Carlile, T.; Gilbert, W. V.

10.1101/271916 — molecular biology — Posted on 2018-02-26

208 An unconventional myosin, myosin 1d regulates Kupffer’s vesicle morphogenesis and laterality

Saydmohammed, M.; Yagi, H.; Calderon, M.; Clark, M. J.; Feinstein, T.; Sun, M.; Stolz, D. B.; Watkins, S. C.; Amack, J.; Lo, C.; Tsang, M.

10.1101/268789 — developmental biology — Posted on 2018-02-26

209 MYC Dysregulates Mitotic Spindle Function Creating a Dependency on TPX2

Rohrberg, J.; Corella, A.; Taileb, M.; Kilinc, S.; Jokisch, M.-L.; Camarda, R.; Zhou, A.; Balakrishnan, S.; Chang, A. N.; Goga, A.

10.1101/272336 — cell biology — Posted on 2018-02-26

210 Revisiting the functional properties of NPF6.3/NRT1.1/CHL1 in xenopus oocytes

Noguero, M.; Leran, S.; Bouguyon, E.; Brachet, C.; Tillard, P.; Nacry, P.; Gojon, A.; Krouk, G.; Lacombe, B.

10.1101/244467 — plant biology — Posted on 2018-02-26

211 Species delimitation and biogeography of the gnatcatchers and gnatwrens (Aves: Polioptilidae)

Smith, B. T.; Bryson, R. W.; Mauck, W. M.; Chaves, J.; Robbins, M. B.; Aleixo, A.; Klicka, J.

10.1101/271494 — evolutionary biology — Posted on 2018-02-26

212 Microzooplankton distribution in the Amundsen Sea Polynya (Antarctica) during an extensive Phaeocystis antarctica bloom

swalethorp, R.; Dinasquet, J.; Logares, R.; Bertilsson, S.; Kjellerup, S.; Krabberod, A.; Moksnes, P.-O.; Nielsen, T.; Riemann, L.

10.1101/271635 — ecology — Posted on 2018-02-26

213 The Ocean Gene Atlas: exploring the biogeography of plankton genes online

Villar, E.; Vannier, T.; Vernette, C.; Lescot, M.; Alexandre, A.; Bachelerie, P.; Rosnet, T.; Pelletier, E.; Sunagawa, S.; Hingamp, P.

10.1101/271882 — bioinformatics — Posted on 2018-02-26

214 Most regulatory interactions are not in linkage disequilibrium

Whalen, S.; Pollard, K. S.

10.1101/272245 — genomics — Posted on 2018-02-26

215 A Methodological Assessment and Characterization of Genetically-Driven Variation in Three Human Phosphoproteomes

Engelmann, B. W.; Hsiao, C. J.; Blischak, J. D.; Fourne, Y.; Ford, M.; Gilad, Y.

10.1101/271650 — genomics — Posted on 2018-02-26

216 Genomic signatures of fine-scale local adaptation in Atlantic salmon suggest involvement of sexual maturation, energy homeostasis, behaviour, and immune defence-related genes.

Pritchard, V. L.; Makinen, H.; Vaha, J.-P.; Erkinaro, J.; Orell, P.; Primmer, C.

10.1101/271528 — evolutionary biology — Posted on 2018-02-26

217 Phospho-regulation of Atoh1 is required for plasticity of secretory progenitors and tissue regeneration

Tomic, G.; Morrissey, E.; Kozar, S.; Ben-Moshe, S.; Hoyle, A.; Azzarelli, R.; Kemp, R.; Chilamakuri, C. S. R.; Itzkovitz, S.; Philpott, A.; Winton, D.

10.1101/268607 — cell biology — Posted on 2018-02-26

218 Activated BAX/BAK enable mitochondrial inner membrane permeabilisation and mtDNA release during cell death

Riley, J.; Quarato, G.; Lopez, J.; O'Prey, J.; Pearson, M.; Chapman, J.; Sesaki, H.; Carlin, L.; Passos, J.; Wheeler, A.; Oberst, A.; Ryan, K.; Tait, S.

10.1101/272104 — cell biology — Posted on 2018-02-26

219 Differential expression of an alternative splice variant of IL-12Rβ1 impacts early dissemination in the mouse and associates with disease outcome in both mouse and humans exposed to tuberculosis

Das, M. K.; Ray, A. A.; Cai, Y.; Singhania, A.; Graham, C.; Liao, M.; Fountain, J. J.; Pearl, J. E.; Pareek, M.; Haldar, P.; O'Garra, A.; Chen, X.; Cooper, A. M.

10.1101/271627 — immunology — Posted on 2018-02-26

220 Cerebral blood flow predicts differential neurotransmitter activity

Dukart, J.; Holiga, S.; Chatham, C.; Hawkins, P.; Forsyth, A.; McMillan, R.; Myers, J.; Lingford-Hughes, A.; Nutt, D.; Merlo-Pich, E.; Risterucci, C.; Umbricht, D.; Boak, L.; Schobel, S.; Liu, T.; Mehta, M.; Zelaya, F.; Williams, S.; Brown, G.; Paulus, M.; Honey, G.; Muthukumaraswamy, S.; Hipp, J.; Bertolino, A.; Sambataro, F.

10.1101/207407 — neuroscience — Posted on 2018-02-26

221 Aspartyl Protease 5 matures virulence factors found at the host-parasite interface in Toxoplasma gondii

Coffey, M. J.; Dagley, L. F.; Kapp, E. A.; Infusini, G.; Boddey, J. A.; Webb, A. I.; Tonkin, C. J.

10.1101/271676 — microbiology — Posted on 2018-02-26

222 Evidence of adhesion and signaling roles for β-catenin in the sponge Ephydatia muelleri

Schippers, K. J.; Nichols, S. A.

10.1101/164012 — evolutionary biology — Posted on 2018-02-26

223 Field evidence for manipulation of mosquito host selection by the human malaria parasite, Plasmodium falciparum

Vantaux, A.; Yao, F.; Hien, D. F.; Guissou, E.; Yameogo, B. K.; Gouagna, L.-C.; Fontenille, D.; Renaud, F.; Simard, F.; Constantini, C.; Thomas, F.; Mouline, K.; Roche, B.; Cohuet, A.; Dabire, K. R.; Lefevre, T.

10.1101/207183 — evolutionary biology — Posted on 2018-02-26

224 Modeling Spatial Genomic Interactions with the Hawkes model

Bonnet, A.; Rivoirard, V.; Picard, F.

10.1101/214874 — bioinformatics — Posted on 2018-02-26

225 MasterPATH: network analysis of functional genomics screening data

Rubanova, N.; Polesskaya, A.; Campalans, A.; Pinna, G.; Kropp, J.; Harel-Bellan, A.; Morozova, N.

10.1101/264119 — systems biology — Posted on 2018-02-26

226 Centrality and the shortest path approach on the human interactome

Rubanova, N.; Morozova, N.

10.1101/264069 — systems biology — Posted on 2018-02-26

227 Sex-biased long non-coding RNAs negatively correlated with sex-opposite protein coding gene co-expression networks in Diversity Outbred mouse liver

Melia, T.; Waxman, D. J.

10.1101/271668 — systems biology — Posted on 2018-02-26

228 Highly efficient CRISPR gene editing in yeast enabled by double selection

Despres, P. C.; Dube, A. K.; Nielly-Thibault, L.; Yachie, N.; Landry, C. R.

10.1101/262808 — synthetic biology — Posted on 2018-02-26

229 Network hubs in root-associated fungal metacommunities

Toju, H.; Tanabe, A. S.; Sato, H.

10.1101/270371 — microbiology — Posted on 2018-02-26

230 Clonal competition in B-cell repertoires during chronic HIV-1 infection

Nourmohammad, A.; Otwinowski, J.; Luksza, M.; Mora, T.; Walczak, A. M.

10.1101/271130 — immunology — Posted on 2018-02-26

231 A simple test identifies selection on complex traits in breeding and experimentally-evolved populations

Beissinger, T. M.; Kruppa, J.; Cavero, D.; Ha, N.-T.; Erbe, M.; Simianer, H.

10.1101/238295 — evolutionary biology — Posted on 2018-02-26

232 Data mining of digitized health records in a resource-constrained setting reveals that timely immunophenotyping is associated with improved breast cancer outcomes

Lopez Pineda, A.; Rodriguez Moran, M. F.; Alvarez Aguilar, C.; Fuentes Valle, S. M.; Acosta Rosales, R.; Bhatt, A. S.; Sheth, S. N.; Bustamante, C. D.

10.1101/198721 — epidemiology — Posted on 2018-02-26

233 Market Smells: Olfactory Detection and Identification in the Built Environment

Hoover, K. C.; Roberts, J.; Berbesque, J. C.

10.1101/270744 — ecology — Posted on 2018-02-26

234 Inhibition and late errors in the antisaccade task: Influence of task design

Aponte, E. A.; Tschan, D. G.; Stephan, K. E.; Heinzle, J.

10.1101/270165 — animal behavior and cognition — Posted on 2018-02-26

235 Biomechanics of the peafowl’s crest: a potential mechanosensory role for feathers during social displays

Kane, S. A.; Van Beveren, D.; Dakin, R.

10.1101/197525 — zoology — Posted on 2018-02-26

236 Sound induces change in orientation preference of V1 neurons: Audio-visual cross-influence

Chanauria, N.; Bharmauria, V.; Bachatene, L.; Cattan, S.; Rouat, J.; Molotchnikoff, S.

10.1101/269589 — neuroscience — Posted on 2018-02-26

237 A Genetic Program Mediates Cold-warming Response and Promotes Stress-induced Phenoptosis in C. elegans

Jiang, W.; Wei, Y.; Long, Y.; Owen, A.; Wang, B.; Wu, X.; Luo, S.; Dang, Y.; Ma, D. K.

10.1101/271106 — genetics — Posted on 2018-02-26

238 Some lessons and perspectives for applications of stochastic models in biological and cancer research

Sabino, A.; Silva Vasconcelos, M. F.; Sittoni, M. Y.; Lautenschlager, W. W.; Queiroga, A. S.; Morais, M. C. C.; Ferreira Ramos, A.

10.1101/270215 — systems biology — Posted on 2018-02-26

239 How prior knowledge prepares perception: Alpha-band oscillations carry perceptual expectations and influence early visual responses

Samaha, J.; Boutonnet, B.; Postle, B.; Lupyan, G.

10.1101/076687 — neuroscience — Posted on 2018-02-26

240 Theta-modulation drives the emergence of network-wide connectivity patterns underlying replay in a a model of hippocampal place cells

Theodoni, P.; Rovira, B.; Wang, Y.; Roxin, A.

10.1101/118489 — neuroscience — Posted on 2018-02-26

241 Task errors contribute to implicit remapping in sensorimotor adaptation

Leow, L.-A.; Marinovic, W.; de rugy, A.; Carroll, T.

10.1101/263988 — neuroscience — Posted on 2018-02-26

242 Sex specific endophenotypes of in-utero cannabinoid exposure

Bara, A.; Manduca, A.; Bernabeu, A.; Borsoi, M.; Servado, M.; Lassalle, O.; Murphy, M. N.; Wager-Miller, J.; Mackie, K.; Pelissier-Alicot, A.-L.; Trezza, V.; Manzoni, O. J.

10.1101/251348 — neuroscience — Posted on 2018-02-26

243 Age differentiation within grey matter, white matter and between memory and white matter in an adult lifespan cohort

de Mooij, S. M. M.; Henson, R. N. A.; Waldorp, L. J.; Cam-CAN, ; Kievit, R. A.

10.1101/148452 — neuroscience — Posted on 2018-02-26

244 Identification of Animal Behavioral Strategies by Inverse Reinforcement Learning

Yamaguchi, S.; Naoki, H.; Ikeda, M.; Tsukada, Y.; Nakano, S.; Mori, I.; Ishii, S.

10.1101/129007 — neuroscience — Posted on 2018-02-26

245 Community-based benchmarking improves spike rate inference from two-photon calcium imaging data

Berens, P.; Freeman, J.; Deneux, T.; Chenkov, N.; McColgan, T.; Speiser, A.; Macke, J. H.; Turaga, S.; Mineault, P.; Rupprecht, P.; Gerhard, S.; Friedrich, R. W.; Friedrich, J.; Paninski, L.; Pachitariu, M.; Harris, K. D.; Bolte, B.; Machado, T. A.; Ringach, D.; Stone, J.; Rogerson, L. E.; Sofroniew, N. J.; Reimer, J.; Froudarakis, E.; Euler, T.; Roman-Roson, M.; Theis, L.; Tolias, A. S.; Bethge, M.

10.1101/177956 — neuroscience — Posted on 2018-02-26

246 Probing the evolutionary robustness of two repurposed drugs targeting iron uptake in Pseudomonas aeruginosa

Rezzoagli, C.; Wilson, D.; Weigert, M.; Wyder, S.; Kuemmerli, R.

10.1101/195974 — microbiology — Posted on 2018-02-26

247 Insulation of gene expression by CTCF and cohesin-based subTADs (ubiquitous intra-TAD loop structures) in mouse liver

Matthews, B. J.; Waxman, D. J.

10.1101/271023 — genomics — Posted on 2018-02-26

248 Complete assembly of parental haplotypes with trio binning

Koren, S.; Rhie, A.; Walenz, B. P.; Dilthey, A. T.; Bickhart, D. M.; Kingan, S. B.; Hiendleder, S.; Williams, J. L.; Smith, T. P. L.; Phillippy, A.

10.1101/271486 — genomics — Posted on 2018-02-26

249 Disarticulating and Reassembling Amphipyrinae (Lepidoptera, Noctuoidea, Noctuidae)

Keegan, K.; Lafontaine, J. D.; Wahlberg, N.; Wagner, D.

10.1101/271478 — evolutionary biology — Posted on 2018-02-26

250 Early Holocene Morphological Variation in Hunter-Gatherer Hands and Feet

Hoover, K. C.; Berbesque, J. C.

10.1101/271460 — evolutionary biology — Posted on 2018-02-26

251 Biased parasitoid sex ratios: Wolbachia, functional traits, local and landscape effects

Laszlo, Z.; Lehel, D. A.; Kiraly, L.; Tothmeresz, B.

10.1101/271395 — ecology — Posted on 2018-02-26

252 TRPM7 residue S1269 mediates cAMP dependence of Ca2+ influx

Broertjes, J.; Klarenbeek, J.; Habani, Y.; Langeslag, M.; Jalink, K.

10.1101/269688 — cell biology — Posted on 2018-02-26

253 Somatic aberrations of BRCA1 gene are associated with progressive and stem cell-like phenotype of prostate cancer

Omari, A.; Nastaly, P.; Balabas, A.; Dabrowska, M.; Bielinska, B.; Huss, S.; Pantel, K.; Semjonow, A.; Eltze, E.; Brandt, B.; Bednarz-Knoll, N.

10.1101/271312 — cancer biology — Posted on 2018-02-26

254 New insights in Tibial muscular dystrophy revealed by protein-protein interaction networks

Leite, G. G. F.; Blighe, K.

10.1101/271411 — bioinformatics — Posted on 2018-02-26

255 Chiron: Translating nanopore raw signal directly into nucleotide sequence using deep learning

Teng, H.; Cao, M. D.; Hall, M. B.; Duarte, T.; Wang, S.; Coin, L.

10.1101/179531 — bioinformatics — Posted on 2018-02-26

256 Insects and incest: sib-mating tolerance in natural populations of a parasitoid wasp

Collet, M.; Amat, I.; Sauzet, S.; Auguste, A.; Fauvergue, X.; Mouton, L.; Desouhant, E.

10.1101/169268 — animal behavior and cognition — Posted on 2018-02-26

257 Rules for PP2A-controlled phosphosignalling and drug responses

Kauko, O.; Imanishi, S. Y.; Kulesskiy, E.; Laajala, T. D.; Yetukuri, L.; Laine, A.; Jumppanen, M.; Haapaniemi, P.; Ruan, L.; Yadav, B.; Suni, V.; Varila, T.; Corthals, G.; Reimand, J.; Wennerberg, K.; Aittokallio, T.; Westermarck, J.

10.1101/271841 — systems biology — Posted on 2018-02-26

258 Epigenetic aging of human hematopoietic cells is not accelerated upon transplantation into mice

Frobel, J.; Rahmig, S.; Franzen, J.; Waskow, C.; Wagner, W.

10.1101/271817 — genomics — Posted on 2018-02-26

259 Pathogen susceptibility and fitness costs explain variation in immune priming across natural populations of flour beetles

Khan, I.; Prakash, A.; Agashe, D.

10.1101/271775 — evolutionary biology — Posted on 2018-02-26

260 Worldwide cross-ecosystem carbon subsidies and their contribution to ecosystem functioning

Gounand, I.; Little, C. J.; Harvey, E.; Altermatt, F.

10.1101/271809 — ecology — Posted on 2018-02-26

261 One man’s trash is another man’s treasure - the effect of bacteria on phytoplankton-zooplankton interactions in chemostat systems

Raatz, M.; Schaelicke, S.; Sieber, M.; Wacker, A.; Gaedke, U.

10.1101/271791 — ecology — Posted on 2018-02-26

262 babette: BEAUti 2, BEAST2 and Tracer for R

Bilderbeek, R. J. C.; Etienne, R. S.

10.1101/271866 — bioinformatics — Posted on 2018-02-26

263 Hypoarousal non-stationary ADHD biomarker based on echo-state networks

Ibanez Soria, D.; Soria-Frisch, A.; Garcia-Ojalvo, J.; Picardo, J.; Garcia-Banda, G.; Servera, M.; Ruffini, G.

10.1101/271858 — bioengineering — Posted on 2018-02-26

264 Distinct impacts of air and root-zone temperatures on leaf and root features of cucumber seedlings: resource acquisition capacity, organ size and carbon-nitrogen balance

Wang, X.; Gao, L.; Tian, Y.

10.1101/271403 — plant biology — Posted on 2018-02-26

265 SELF-PRUNING affects auxin responses synergistically with the cyclophilin A DIAGEOTROPICA in tomato

Silva, W. B.; Vicente, M. H.; Moncaleano, J. R.; Reartes, D. S.; Ferrari, R. C.; Bianchetti, R.; Araujo, W. L.; Freschi, L.; Peres, L. E.; Zsögön, A.

10.1101/271387 — plant biology — Posted on 2018-02-26

266 Metabolomics and proteomics analyses of grain yield reduction in rice under abrupt drought-flood alternation

Xiong, Q.; Chen, X.; Shen, T.; Zhong, L.; Zhu, C.; Peng, X.; He, X.; Fu, J.; Ouyang, L.; Bian, J.; Hu, L.; Sun, X.; Xu, J.; Zhou, D.; Zhou, H.; He, H.

10.1101/271940 — plant biology — Posted on 2018-02-26

267 Identification of changing ribosome protein compositions using cryo-EM and mass spectrometry

Frank, J.

10.1101/271833 — microbiology — Posted on 2018-02-26

268 bpRNA: Large-scale Automated Annotation and Analysis of RNA Secondary Structure

Danaee, P.; Rouches, M.; Wiley, M.; Deng, D.; Huang, L.; Hendrix, D. A.

10.1101/271759 — bioinformatics — Posted on 2018-02-26

269 Long-term live imaging of the Drosophila adult midgut reveals real-time dynamics of cell division, differentiation, and loss

Martin, J.; Sanders, E. N.; Moreno-Roman, P.; Balachandra, S.; Du, X.; Jaramillo Koyama, L. A.; O'Brien, L. E.

10.1101/271742 — cell biology — Posted on 2018-02-26

270 The dynamic tumor ecosystem: how cell turnover and trade-offs affect cancer evolution

Gallaher, J.; Brown, J.; Anderson, A. R. A.

10.1101/270900 — ecology — Posted on 2018-02-26

271 Complementary, Semi-automated Methods for Creating Multi-dimensional, PEG-based Biomaterials

Brooks, E. A.; Jansen, L. E.; Gencoglu, M. F.; Yurkevicz, A. M.; Peyton, S.

10.1101/219501 — bioengineering — Posted on 2018-02-26

272 Dbx1 pre-Bötzinger complex interneurons comprise the core inspiratory oscillator for breathing in adult mice

Vann, N. C.; Pham, F. D.; Dorst, K. E.; Del Negro, C. A.

10.1101/271585 — neuroscience — Posted on 2018-02-25

273 On variational solutions for whole brain serial-section histology using the computational anatomy random orbit model

Lee, B. C.; Tward, D. J.; Mitra, P. P.; Miller, M.

10.1101/271692 — neuroscience — Posted on 2018-02-25

274 Confidence as a diagnostic tool for perceptual aftereffects

Gallagher, R.; Suddendorf, T.; Arnold, D.

10.1101/270280 — neuroscience — Posted on 2018-02-25

275 GTSF-1 is required for the formation of a functional RNA-dependent RNA Polymerase complex in C. elegans

Almeida, M. V.; Dietz, S.; Redl, S.; Karaulanov, E.; Hildebrandt, A.; Renz, C.; Ulrich, H. D.; König, J.; Butter, F.; Ketting, R. F.

10.1101/271270 — molecular biology — Posted on 2018-02-25

276 A bHLH-PAS protein regulates light-dependent rhythmic processes in the marine diatom Phaeodactylum tricornutum

Annunziata, R.; Ritter, A.; Fortunato, A. E.; Cheminant-Navarro, S.; Agier, N.; Huysman, M. J. J.; Winge, P.; Bones, A.; Bouget, F.-Y.; Cosentino Lagomarsino, M.; Bouly, J. P.; Falciatore, A.

10.1101/271445 — molecular biology — Posted on 2018-02-25

277 The exon junction complex regulates the release and phosphorylation of paused RNA polymerase II

Akhtar, J.; Kreim, N.; Marini, F.; Kumar Mohana, G.; Brune, D.; Binder, H.; Roignant, J.-Y.

10.1101/271544 — molecular biology — Posted on 2018-02-25

278 Multiple Small RNAs Alter Membrane Lipid Composition via Post-Transcriptional Regulation of Cyclopropane Fatty Acid Synthase

Bianco, C. M.; Vanderpool, C. K.

10.1101/271551 — microbiology — Posted on 2018-02-25

279 The role of AP-1 in self-sufficient proliferation and migration of cancer cells and its potential impact on an autocrine/paracrine loop.

Abudu, A.; Ibrahim, S.; Johnson, E.; Aftab, N.; Fluck, M.

10.1101/271536 — cancer biology — Posted on 2018-02-25

280 Correlating enzyme annotations with a large set of microbial growth temperatures reveals metabolic adaptations to growth at diverse temperatures

Engqvist, M. K.

10.1101/271569 — bioinformatics — Posted on 2018-02-25

281 Cas-CLIP: a method for customizing pooled CRISPR libraries

Kweon, J.; Kim, D.-e.; Jang, A.-H.; Kim, Y.

10.1101/187757 — bioengineering — Posted on 2018-02-25

282 Cross-Platform Mechanical Characterization of Lung Tissue

Polio, S.; Kundu, A.; Dougan, C.; Birch, N.; Aurien-Blajeni, D. E.; Schiffman, J.; Crosby, A.; Peyton, S.

10.1101/271726 — bioengineering — Posted on 2018-02-25

283 Controlling insulin resistance through modulation of interplay between mediators of cellular senescence: A mathematical study

Arora, C.

10.1101/269738 — systems biology — Posted on 2018-02-25

284 Spores and soil from six sides: interdisciplinarity and the environmental biology of anthrax (Bacillus anthracis)

Carlson, C. J.; Getz, W.; Kausrud, K.; Cizauskas, C.; Blackburn, J.; Bustos Carrillo, F. A.; Colwell, R.; Easterday, W. R.; Ganz, H.; Kamath, P.; Okstad, O. A.; Turner, W.; Kolsto, A.-B.; Stenseth, N. C.

10.1101/165548 — ecology — Posted on 2018-02-25

285 History is written by the victors: the effect of the push of the past on the fossil record

Budd, G. E.; Mann, R. P.

10.1101/194753 — paleontology — Posted on 2018-02-25

286 CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts

Noe Gonzalez, M.; Sato, S.; Tomomori-Sato, C.; Conaway, J. W.; Conaway, R. C.

10.1101/269977 — molecular biology — Posted on 2018-02-25

287 Multivariate genotypic analyses that identify specific genotypes to characterize disease and control groups in ADNI

Beaton, D.; Rieck, J.; Alhazmi, F.; the Alzheimer's Disease Neuroimaging Initiative, ; Abdi, H.

10.1101/235945 — genomics — Posted on 2018-02-25

288 Firefly genomes illuminate parallel origins of bioluminescence in beetles

Fallon, T. R.; Lower, S. E.; Chang, C.-H.; Bessho-Uehara, M.; Martin, G. J.; Bewick, A. J.; Behringer, M.; Debat, H. J.; Wong, I.; Day, J. C.; Suvorov, A.; Silva, C. J.; Stanger-Hall, K. F.; Hall, D. W.; Schmitz, R. J.; Nelson, D. R.; Lewis, S.; Shigenobu, S.; Bybee, S. M.; Larracuente, A. M.; Oba, Y.; Weng, J.-K.

10.1101/237586 — genomics — Posted on 2018-02-25

289 Impacts of predators, habitat, recruitment, and disease on soft-shell clams Mya arenaria and stout razor clams Tagelus plebeius in Chesapeake Bay

Glaspie, C. N.; Seitz, R. D.; Ogburn, M. B.; Dungan, C. F.; Hines, A. H.

10.1101/224071 — ecology — Posted on 2018-02-25

290 Maize GO Annotation - Methods, Evaluation, and Review (maize-GAMER)

Wimalanathan, K.; Friedberg, I.; Andorf, C. M.; Lawrence-Dill, C. J.

10.1101/222836 — bioinformatics — Posted on 2018-02-25

291 Directed Conservative Causal Core Gene Networks

Altay, G.

10.1101/271031 — bioinformatics — Posted on 2018-02-25

292 Addressing the looming identity crisis in single cell RNA-seq

Crow, M.; Paul, A.; Ballouz, S.; Huang, Z. J.; Gillis, J.

10.1101/150524 — bioinformatics — Posted on 2018-02-25

293 Insects and incest: sib-mating tolerance in natural populations of a parasitoid wasp

Collet, M.; Amat, I.; Sauzet, S.; Auguste, A.; Fauvergue, X.; Mouton, L.; Desouhant, E.

10.1101/169268 — animal behavior and cognition — Posted on 2018-02-25

294 MCRiceRepGP: a framework for identification of sexual reproduction associated coding and lincRNA genes in rice.

Golicz, A. A.; Bhalla, P. L.; Singh, M. B.

10.1101/271353 — plant biology — Posted on 2018-02-25

295 Interhemispheric Integration for Complex Behaviors, Absent the Corpus Callosum in Normal Ontogeny

Layden, E. A.; Schertz, K. E.; London, S. E.; Berman, M. G.

10.1101/271072 — neuroscience — Posted on 2018-02-25

296 Generating perfusion maps from structural optical coherence tomography with artificial intelligence

Lee, C. S.; Tyring, A. J.; Wu, Y.; Xiao, S.; Rokem, A. S.; Deruyter, N. P.; Zhang, Q.; Tufail, A.; Wang, R. K.; Lee, A.

10.1101/271346 — neuroscience — Posted on 2018-02-25

297 Top-down inputs drive neuronal network rewiring and context-enhanced sensory processing in olfaction

Adams, W.; Graham, J. N.; Han, X.; Riecke, H.

10.1101/271197 — neuroscience — Posted on 2018-02-25

298 Systematic differences between visually-relevant global and local image statistics of brain MRI and natural scenes

Xu, S.; Raj, A.; Victor, J. D.; Alzheimer's Disease Neuroimaging Initiative,

10.1101/271338 — neuroscience — Posted on 2018-02-25

299 Seasonal influenza circulation patterns and projections for Feb 2018 to Feb 2019

Bedford, T.; Neher, R.

10.1101/271114 — evolutionary biology — Posted on 2018-02-25

300 Relationship between Acropora millepora juvenile fluorescence and composition of newly established Symbiodinium assemblage

Quigley, K.; Strader, M.; Matz, M.

10.1101/271155 — ecology — Posted on 2018-02-25

301 Serial Dependence in Position Perception Occurs at the Time of Perception

Manassi, M.; Liberman, A.; Kosovicheva, A.; Zhang, K.; Whitney, D.

10.1101/270272 — neuroscience — Posted on 2018-02-25

302 Membrane proteins with high N-glycosylation, high expression, and multiple interaction partners were preferred by mammalian viruses as receptors

Zhang, Z.; Zhu, Z.; Chen, W.; Cai, Z.; Xu, B.; Tan, Z.; Wu, A.; Ge, X.; Guo, X.; Tan, Z.; Xia, Z.; Zhu, H.; Jiang, T.; Peng, Y.

10.1101/271171 — microbiology — Posted on 2018-02-25

303 A linear mixed model approach to study multivariate gene-environment interactions

Moore, R.; Casale, F. P.; Bonder, M. J.; Horta, D.; BIOS Consortium, ; Franke, L.; Barroso, I.; Stegle, O.

10.1101/270611 — genetics — Posted on 2018-02-25

304 Comparative metabolomics of forest communities: Species differences in foliar chemistry are greater in the tropics.

Sedio, B. E.; Parker, J. D.; McMahon, S. M.; Wright, S. J.

10.1101/271361 — ecology — Posted on 2018-02-25

305 Directed Conservative Causal Core Gene Networks

Altay, G.

10.1101/271031 — bioinformatics — Posted on 2018-02-25

306 Parallelized Inference for Single Cell Transcriptomic Clustering with Split Merge Sampling on DPMM Model

Duan, T.; Pinto, J. P.; Xie, X.

10.1101/271163 — bioinformatics — Posted on 2018-02-25

307 Animal learning in amultidimensional discrimination task as explained by dimension-specific allocation of attention

Aluisi, F.; Rubinchik, A.; Morris, G.

10.1101/271379 — animal behavior and cognition — Posted on 2018-02-25

308 Quantitative Temporal Analysis of Protein Dynamics in Maladaptive Cardiac Remodeling

McClatchy, D. B.; ma, y.; Liem, D. A.; Ng, D. C. M.; Ping, P.; Yates, J. R.

10.1101/270959 — pathology — Posted on 2018-02-24

309 Arabidopsis inositol phosphate kinases, IPK1 and ITPK1, constitute a metabolic pathway in maintaining phosphate homeostasis

Kuo, H.-F.; Hsu, Y.-Y.; Lin, W.-C.; Chen, K.-Y.; Munnik, T.; Brearley, C.; Chiou, T.-J.

10.1101/270355 — plant biology — Posted on 2018-02-24

310 Within-host recombination in structural proteins of the Foot-and-Mouth Disease Virus

Ferretti, L.; Perez, E.; Zhang, F.; Maree, F.; Charleston, B.; Ribeca, P.

10.1101/271239 — microbiology — Posted on 2018-02-24

311 The contraction in inverted repeat regions in the complete plastome sequence of Cressa cretica L

Thaker, V. S.; Bhatt, P. P.

10.1101/271221 — genomics — Posted on 2018-02-24

312 A Genetic Program Mediates Cold-warming Response and Promotes Stress-induced Phenoptosis in C. elegans

Jiang, W.; Wei, Y.; Long, Y.; Owen, A.; Wang, B.; Wu, X.; Luo, S.; Dang, Y.; Ma, D.

10.1101/271106 — genetics — Posted on 2018-02-24

313 Dynamic interplay of innate and adaptive immunity during sterile retinal inflammation: Insights from the transcriptome

Natoli, R.; Mason, E.; Jiao, H.; Chuah, A.; Patel, H.; Fernando, N.; Valter, K.; Wells, C. A.; Provis, J.; Rutar, M.

10.1101/267757 — neuroscience — Posted on 2018-02-24

314 Clonal competition in B-cell repertoires during chronic HIV-1 infection

Nourmohammad, A.; Otwinowski, J.; Luksza, M.; Walczak, A. M.; Mora, T.

10.1101/271130 — immunology — Posted on 2018-02-24

315 Sensitive periods for the effect of childhood adversity on DNA methylation: Results from a prospective, longitudinal study

Dunn, E. C.; Soare, T. W.; Simpkin, A. J.; Suderman, M. J.; Zhu, Y.; Klengel, T.; Smith, A. D. A. C.; Ressler, K.; Relton, C. L.

10.1101/271122 — genetics — Posted on 2018-02-24

316 Yeast heterochromatin regulators Sir2 and Sir3 act directly at euchromatic DNA replication origins

Hoggard, T.; Chang, F.; Perry, K. R.; Subramanian, S.; Kenworthy, J.; Chueng, J.; Shor, E.; Cosgrove, M.; Boeke, J.; Fox, C. A.; Weinreich, M.

10.1101/271304 — genetics — Posted on 2018-02-24

317 Predicting Evolutionarily Stable Strategies from Functional Trade-offs of Sonoran Desert Annuals

Cuello, W. S.; Gremer, J.; Trimmer, P.; Sih, A.; Schreiber, S.

10.1101/271080 — ecology — Posted on 2018-02-24

318 Regulation of midgut cell proliferation impacts Aedes aegypti susceptibility to dengue virus

Taracena, M. L.; Bottino-Rojas, V.; Talyuli, O. A. C.; Walter-Nuno, A. B.; Oliveira, J. H. M.; Anglero-Rodriguez, Y. I.; Wells, M. B.; Dimopoulos, G.; Oliveira, P. L.; Paiva-Silva, G. O.

10.1101/271288 — cell biology — Posted on 2018-02-24

319 Causal interactions from proteomic profiles: molecular data meets pathway knowledge

Babur, O.; Luna, A.; Korkut, A.; Durupinar, F.; Siper, M. C.; Dogrusoz, U.; Aslan, J. E.; Sander, C.; Demir, E.

10.1101/258855 — systems biology — Posted on 2018-02-24

320 Gender balance in time-keeping at life science conferences

Edlund, P.; Tranfield, E. M.; van Noort, V.; Siu Ting, K.; Tapani, S.; Hoog, J.

10.1101/267120 — scientific communication and education — Posted on 2018-02-24

321 A High-Throughput Pipeline Identifies Robust Connectomes But Troublesome Variability

Kiar, G.; Bridgeford, E.; Roncal, W. G.; Consortium for Reliability and Reproducibliity (CoRR), ; Chandrashekhar, V.; Mhembere, D.; Ryman, S.; Zuo, X.-N.; Marguiles, D. S.; Craddock, R. C.; Priebe, C. E.; Jung, R.; Calhoun, V.; Caffo, B.; Burns, R.; Milham, M. P.; Vogelstein, J.

10.1101/188706 — neuroscience — Posted on 2018-02-24

322 The Opportunity Cost of Time Modulates Cognitive Effort

Otto, A. R.; Daw, N.

10.1101/201863 — neuroscience — Posted on 2018-02-24

323 nPIST: A Novel Actin Binding Protein of trans-Golgi Network

Maiti, S.; Das, S.; Dutta, P.; Mazumder, M.; Seal, S.; Duraivelan, K.; Samanta, D.; Gourinath, S.

10.1101/270363 — cell biology — Posted on 2018-02-24

324 An Interpretable Framework for Clustering Single-Cell RNA-Seq Datasets

Zhang, J. M.; Fan, J.; Fan, H. C.; Rosenfeld, D.; Tse, D. N.

10.1101/191254 — bioinformatics — Posted on 2018-02-24

325 Partial-Width Injuries of the Rat Rotator Cuff Heal with Fibrosis

Lemmon, E. A.; Locke, R. C.; Szostek, A. K.; Killian, M. L.

10.1101/268920 — bioengineering — Posted on 2018-02-24

326 The microbiome and metabolome of pre-term infant stool is personalized, and not driven by health outcomes including necrotizing enterocolitis and late-onset sepsis

Wandro, S.; Osborne, S.; Enriquez, C.; Bixby, C.; Arrieta, A.; Whiteson, K.

10.1101/125922 — microbiology — Posted on 2018-02-24

327 Pervasive epistasis modulates neurodevelopmental defects of the autism-associated 16p11.2 deletion

10.1101/185355 — genomics — Posted on 2018-02-24

328 Full likelihood inference from the site frequency spectrum based on the optimal tree resolution

Sainudiin, R.; Veber, A.

10.1101/181412 — genetics — Posted on 2018-02-24

329 Fractal Features of Proto-Plant’s Origin and their Possible Consequences

Galitskii, V. V.

10.1101/083543 — evolutionary biology — Posted on 2018-02-24

330 Neither pulled nor pushed: Genetic drift and front wandering uncover a new class of reaction-diffusion waves

Birzu, G.; Hallatschek, O.; Korolev, K. S.

10.1101/183806 — ecology — Posted on 2018-02-24

331 GenomeDISCO: A concordance score for chromosome conformation capture experiments using random walks on contact map graphs

Ursu, O.; Boley, N.; Taranova, M.; Wang, Y. X. R.; Yardimci, G. G.; Noble, W. S.; Kundaje, A.

10.1101/181842 — bioinformatics — Posted on 2018-02-24

332 Efficient differentiation of vascular endothelial cells from dermal-derived mesenchymal stem cells induced by endothelial cell lines conditioned medium

Zhou, L.; Niu, X.; Liang, J.; Li, J.; Li, J.; Cheng, Y.; Meng, Y.; Wang, Q.; Yang, X.; Wang, G.; Shi, Y.; Dang, E.; Zhang, K.

10.1101/271148 — cell biology — Posted on 2018-02-24

333 Nicotinic cholinergic receptors in VTA glutamate neurons modulate excitatory transmission

Yan, Y.; Peng, C.; Arvin, M. C.; Jin, X.-T.; Kim, V. J.; Ramsey, M. D.; Wang, Y.; Banala, S.; Wokosin, D. L.; McIntosh, J. M.; Lavis, L. D.; Drenan, R. M.

10.1101/271205 — neuroscience — Posted on 2018-02-24

334 Lung Cancer Explorer (LCE): an open web portal to explore gene expression and clinical associations in lung cancer

Cai, L.; Lin, S.; Zhou, Y.; Yang, L.; Ci, B.; Zhou, Q.; Luo, D.; Yao, B.; Tang, H.; Allen, J.; Huffman, K.; Gazdar, A.; Heymach, J.; Wistuba, I.; Xiao, G.; Minna, J.; Xie, Y.

10.1101/271056 — cancer biology — Posted on 2018-02-24

335 ProxECAT: Proxy External Controls Association Test. A new case-control gene region association test using allele frequencies from public controls

Hendricks, A. E.; Billups, S.; Pike, H. N.; Farooqi, I. S.; Zeggini, E.; Barroso, I.; Dupuis, J.

10.1101/271007 — genetics — Posted on 2018-02-24

336 Emergence of evolutionary stable communities through eco-evolutionary tunneling

Kotil, S. E.; Vetsigian, K.

10.1101/271015 — evolutionary biology — Posted on 2018-02-24

337 Do pneumococcal conjugate vaccines (PCVs) reduce childhood pneumonia mortality? An assessment across socioeconomic groups in Brazil

Schuck-Paim, C.; Taylor, R. M.; Alonso, W. J.; Weinberger, D. M.; Simonsen, L.

10.1101/270637 — epidemiology — Posted on 2018-02-24

338 Interim impact evaluation of the hepatitis C virus elimination program in Georgia

Walker, J. G.; Lim, A. G.; Fraser, H.; Gvinjilia, L.; Hagan, L.; Kuchuloria, T.; Martin, N.; Nasrullah, M.; Shadaker, S.; Aladashvili, M.; Asatiani, A.; Baliashvili, D.; Butsashvili, M.; Chikovani, I.; Khonelidze, I.; Kirtadze, I.; Kuniholm, M.; Otiashvili, D.; Stvilia, K.; Tsertsvadze, T.; Hickman, M.; Morgan, J.; Gamkrelidze, A.; Kvaratskhelia, V.; Averhoff, F.; Vickerman, P.

10.1101/270579 — epidemiology — Posted on 2018-02-24

339 Enhancer RNAs are necessary and sufficient for activity-dependent neuronal gene transcription

Gallus, N. V. N.; Simon, R. A.; Salisbury, A. J.; Revanna, J. S.; Bunner, K. D.; Savell, K. E.; Sultan, F. A.; Gersbach, C. A.; Day, J. J.

10.1101/270967 — neuroscience — Posted on 2018-02-23

340 Brainstem control of urethral sphincter relaxation and scent marking behavior

Keller, J. A.; Chen, J.; Simpson, S.; Wang, E. H.-J.; Lilascharoen, V.; George, O.; Lim, B. K.; Stowers, L.

10.1101/270801 — neuroscience — Posted on 2018-02-23

341 SAMHD1 Impairs HIV-1 Gene Expression and Reactivation of Viral Latency in CD4+ T-cells

Antonucci, J. M.; Kim, S. H.; St. Gelais, C.; Bonifati, S.; Buzovetsky, O.; Knecht, K.; Duchon, A. A.; Xiong, Y.; Musier-Forsyth, K. M.; Wu, L.

10.1101/270843 — microbiology — Posted on 2018-02-23

342 Streptococcal Lancefield polysaccharides are critical cell wall determinants for human group IIA secreted phospholipase A2 to exert its bactericidal effects

van Hensbergen, V. P.; Movert, E.; de Maat, V.; Le Breton, Y.; Lambeau, G.; Payre, C.; Henningham, A.; Nizet, V.; Van Strijp, J. A. G.; Carlsson, F.; McIver, K. S.; van Sorge, N. M.

10.1101/269779 — microbiology — Posted on 2018-02-23

343 Network hubs in root-associated fungal metacommunities

Toju, H.; Tanabe, A. S.; Sato, H.

10.1101/270371 — microbiology — Posted on 2018-02-23

344 Statistical Significance of Cluster Membership with Applications to High-Throughput Genomic Data

Chung, N. C.

10.1101/248633 — genomics — Posted on 2018-02-23

345 A comprehensive assessment of benign genetic variability for neurodegenerative disorders

Guerreiro, R.; Sassi, C.; Gibbs, J.; Edsall, C.; Hernandez, D.; Brown, K.; Lupton, M.; Parkinnen, L.; Ansorge, O.; Hodges, A.; Ryten, M.; Tienari, P.; Van Deerlin, V.; Trojanowski, J.; Morgan, K.; Powell, J.; Singleton, A.; Hardy, J.; Bras, J.

10.1101/270686 — genomics — Posted on 2018-02-23

346 Epigenomic convergence of genetic and immune risk factors in autism brain

Vogel Ciernia, A.; Laufer, B. I.; Dunaway, K. W.; Mordaunt, C. E.; Coulson, R. L.; Yasui, D. H.; LaSalle, J. M.

10.1101/270827 — genomics — Posted on 2018-02-23

347 Elongation during segmentation shows axial variability, low mitotic rates, and synchronized cell cycle domains in the crustacean, Thamnocephalus platyurus

Constantinou, S. J.; Duan, N.; Chipman, A. D.; Nagy, L. M.; Williams, T. A.

10.1101/270728 — developmental biology — Posted on 2018-02-23

348 Classification of breast tumours into molecular apocrine, luminal and basal groups based on an explicit biological model

Iggo, R. D.

10.1101/270975 — cancer biology — Posted on 2018-02-23

349 Improved protein model quality assessments by changing the target function

Uziela, K.; Menendez Hurtado, D.; Shu, N.; Wallner, B.; Elofsson, A.

10.1101/270678 — bioinformatics — Posted on 2018-02-23

350 Robustness encoded across essential and accessory replicons in an ecologically versatile bacterium

diCenzo, G. C.; Benedict, A. B.; Fondi, M.; Walker, G. C.; Finan, T. M.; Mengoni, A.; Griffitts, J. S.

10.1101/209916 — systems biology — Posted on 2018-02-23

351 Probing the network structure of health deficits in human aging

Farrell, S. G.; Mitnitski, A. B.; Theou, O.; Rockwood, K.; Rutenberg, A. D.

10.1101/270876 — systems biology — Posted on 2018-02-23

352 Amplification and Suppression of Distinct Brain-wide Activity Patterns by Catecholamines

van den Brink, R. L.; Nieuwenhuis, S.; Donner, T. H.

10.1101/270645 — neuroscience — Posted on 2018-02-23

353 Household Transmission Study of Cryptosporidiosis in Bangladesh

Korpe, P. S.; Gilchrist, C.; Burkey, C.; Ahmed, E.; Madan, V.; Castillo, R.; Ahmed, S.; Arju, T.; Alam, M.; Kabir, M.; Petri, W. A.; Haque, R.; Faruque, A. S. G.; Duggal, P.

10.1101/269985 — microbiology — Posted on 2018-02-23

354 Is this a fake QTL? A short note on analysis of multiple QTL peaks on the same chromosome

Lorieux, M.

10.1101/270736 — genetics — Posted on 2018-02-23

355 Market Smells: Olfactory Detection and Identification in the Built Environment

Hoover, K. C.; Berbesque, J. C.; Roberts, J.

10.1101/270744 — ecology — Posted on 2018-02-23

356 Characterization of convergent thickening, a major convergence force producing morphogenic movement in amphibians

Shook, D. R.; Wen, J.; Rolo, A.; Francica, B.; Dobins, D.; Skoglund, P.; DeSimone, D.; Winklbauer, R.; Keller, R.

10.1101/270892 — developmental biology — Posted on 2018-02-23

357 Regulator of calcineurin-2 is a centriolar protein with a role in cilia length control

Stevenson, N.; Bergen, D.; Xu, A.; Wyatt, E.; Henry, F.; McCaughey, J.; Vuolo, L.; Hammond, C.; Stephens, D.

10.1101/188946 — cell biology — Posted on 2018-02-23

358 OMEGA: a software tool for the management, analysis, and dissemination of intracellular trafficking data that incorporates motion type classification and quality control

Rigano, A.; Galli, V.; Clark, J. M.; Pereira, L. E.; Grossi, L.; Luban, J.; Giulietti, R.; Leidi, T.; Hunter, E.; Valle, M.; Sbalzarini, I. F.; Strambio-De-Castillia, C.

10.1101/251850 — bioinformatics — Posted on 2018-02-23

359 TAG.ME: Taxonomic Assignment of Genetic Markers for Ecology

Pires, D. E. V.; Oliveira, F. S.; Correa, F. B.; Morais, D. K.; Fernandes, G. R.

10.1101/263293 — bioinformatics — Posted on 2018-02-23

360 Why do eukaryotic proteins contain more intrinsically disordered regions?

Basile, W.; Elofsson, A.

10.1101/270694 — bioinformatics — Posted on 2018-02-23

361 First data-driven approach to using individual cattle weights to estimate mean adult dairy cattle weight in the UK

Schubert, H. E.; Wood, S.; Reyher, K.; Mills, H.

10.1101/270702 — animal behavior and cognition — Posted on 2018-02-23

362 meaRtools: an R package for the Comprehensive Analysis of Neuronal Networks Recorded on Multi-Electrode Arrays

Gelfman, S.; Wang, Q.; Lu, Y.-F.; Hall, D.; Bostick, C.; Dhindsa, R.; Halvorsen, M.; McSweeney, K. M.; Cotterill, E.; Edinburgh, T.; Beaumont, M.; Frankel, W. N.; Petrovski, S.; Boland, M. J.; Allen, A. S.; Goldstein, D. B.; Eglen, S. J.

10.1101/242065 — neuroscience — Posted on 2018-02-23

363 A microtubule-based mechanism predicts cell division orientation in plant embryogenesis

Chakrabortty, B.; Willemsen, V.; Zeeuw, T. d.; Liao, C.-Y.; Weijers, D.; Mulder, B.; Scheres, B.

10.1101/270793 — developmental biology — Posted on 2018-02-23

364 Hedgehog signaling controls progenitor differentiation timing during heart development

Rowton, M.; Hoffmann, A. D.; Steimle, J. D.; Yang, X. H.; Guzzetta, A.; Lazarevic, S.; Kim, C.; Deng, N.; Lu, E.; Jacobs-Li, J.; Yu, S.; Hanson, E.; Perez-Cervantes, C.; Chan, S. S.-K.; Ikegami, K.; Garry, D. J.; Kyba, M.; Moskowitz, I. P.

10.1101/270751 — developmental biology — Posted on 2018-02-23

365 Inhibitory and late errors in the antisaccade task: Influence of task design

Aponte, E. A.; Tschan, D. G.; Stephan, K. E. E.; Heinzle, J.

10.1101/270165 — animal behavior and cognition — Posted on 2018-02-23

366 Novel Quantitative ChIP-seq Methods Measure Absolute Fold-Change in ER Binding Upon Fulvestrant Treatment

Guertin, M. J.; Cullen, A. E.; Markowetz, F.; Holding, A. N.

10.1101/182261 — genomics — Posted on 2018-02-23

367 Reverse immunodynamics: a new method to identifying targets of protective immunity.

Spensley, K. J.; Wikramaratna, P. S.; Penman, B. S.; Walker, A.; Smith, A. L.; Pybus, O. G.; Jean, L.; Gupta, S.; Lourenco, J.

10.1101/159483 — epidemiology — Posted on 2018-02-23

368 Modeling cell-substrate de-adhesion dynamics under fluid shear

Maan, R.; Menon, G. I.; Pullarkat, P. A.

10.1101/166371 — biophysics — Posted on 2018-02-23

369 Utilizing a resource of enrichment profiles in plasma for the systematic assessment of antibody selectivity.

Fredolini, C.; Bystrom, S.; Sanchez-Rivera, L.; Ioannou, M.; Tamburro, D.; Branca, R. M.; Nilsson, P.; Lehtio, J.; Schwenk, J. M.

10.1101/158022 — biochemistry — Posted on 2018-02-23

370 Quantitative understanding of molecular competition as a hidden layer of gene regulatory network

Yuan, Y.; Wei, L.; Hu, T.; Li, S.; Cheng, T.; Lei, J.; Xie, Z.; Zhang, M. Q.; Wang, X.

10.1101/258129 — systems biology — Posted on 2018-02-23

371 Bioscience-scale automated detection of figure element reuse

Acuna, D. E.; Brookes, P. S.; Kording, K. P.

10.1101/269415 — scientific communication and education — Posted on 2018-02-23

372 Yield of Universal Testing for DNA Mismatch Repair Protein Deficiency in Colorectal Carcinoma From an Australian Community-based Practice

Miller, G. C.; Bettington, M. L.; Brown, I. S.; Rosty, C.

10.1101/270322 — pathology — Posted on 2018-02-23

373 Huge intrinsic correlation between developmental prosopagnosia questionnaires: A comment on Shah et al. (2015)

Matsuyoshi, D.; Watanabe, K.

10.1101/267351 — neuroscience — Posted on 2018-02-23

374 Does impedance matter when recording spikes with polytrodes?

Neto, J. P.; Baiao, P.; Lopes, G.; Frazao, J.; Nogueira, J.; Fortunato, E.; Barquinha, P.; Kampff, A. R.

10.1101/270058 — neuroscience — Posted on 2018-02-23

375 3D Axonal Morphometry of White Matter

Abdollahzadeh, A.; Belevich, I.; Jokitalo, E.; Tohka, J.; Sierra, A.

10.1101/239228 — neuroscience — Posted on 2018-02-23

376 Deconstructing Procedural Memory: Different Learning Trajectories and Consolidation of Sequence and Statistical Learning

Simor, P.; Zavecz, Z.; Horvath, K.; Elteto, N.; Torok, C.; Pesthy, O.; Gombos, F.; Janacsek, K.; Nemeth, D.

10.1101/216374 — neuroscience — Posted on 2018-02-23

377 Dynamics of pellet fragmentation in liquid-grown cultures of Streptomyces lividans

Zacchetti, B.; Smits, P.; Claessen, D.

10.1101/270595 — microbiology — Posted on 2018-02-23

378 The development of gut microbiota in ostriches and its association with juvenile growth

Videvall, E.; Song, S. J.; Bensch, H. M.; Strandh, M.; Engelbrecht, A.; Serfontein, N.; Hellgren, O.; Olivier, A.; Cloete, S.; Knight, R.; Cornwallis, C. K.

10.1101/270017 — microbiology — Posted on 2018-02-23

379 The fungal ligand chitin directly binds and signals inflammation dependent on oligomer size and TLR2

Fuchs, K.; Cardona Gloria, Y.; Wolz, O.-O.; Herster, F.; Sharma, L.; Dillen, C.; Täumer, C.; Dickhöfer, S.; Bittner, Z.; Dang, T.-M.; Singh, A.; Haischer, D.; Schlöffel, M. A.; Koymans, K. J.; Sanmuganantham, T.; Krach, M.; Schilling, N. A.; Frauhammer, F.; Miller, L.; Nürnberger, T.; LeibundGut-Landmann, S.; Gust, A. A.; Macek, B.; Frank, M.; Gouttefangeas, C.; Dela-Cruz, C. S.; Hartl, D.; Weber, A.

10.1101/270405 — immunology — Posted on 2018-02-23

380 Rare germline variants in Fanconi Anemia genes increase risk for squamous lung cancer

Esai Selvan, M.; Klein, R. J.; Gumus, Z. H.

10.1101/269837 — genomics — Posted on 2018-02-23

381 Best Practices for Benchmarking Germline Small Variant Calls in Human Genomes

Krusche, P.; Trigg, L.; Boutros, P. C.; Mason, C. E.; De La Vega, F. M.; Moore, B. L.; Gonzalez-Porta, M.; Eberle, M. A.; Tezak, Z.; Labadibi, S.; Truty, R.; Asimenos, G.; Funke, B.; Fleharty, M.; Salit, M.; Zook, J. M.; Global Alliance for Genomics and Health Benchmarking Team,

10.1101/270157 — genomics — Posted on 2018-02-23

382 Common practice tissue extraction in solvent does not reflect actual emission of a sex pheromone during courtship in a butterfly

Visser, B.; Dublon, I.; Heuskin, S.; Laval, F.; Bacquet, P.; Lognay, G.; Nieberding, C.

10.1101/270462 — evolutionary biology — Posted on 2018-02-23

383 The TMEM16A Channel Mediates the fast polyspermy block in Xenopus Laevis

Wozniak, K. L.; Phelps, W. A.; Tembo, M.; Lee, M. T.; Carlson, A. E.

10.1101/270629 — developmental biology — Posted on 2018-02-23

384 Integrin signaling downregulates filopodia in muscle-tendon attachment

Richier, B.; Inoue, Y.; Dobramysl, U.; Friedlander, J.; Brown, N. H.; Gallop, J. L.

10.1101/270546 — developmental biology — Posted on 2018-02-23

385 Sexual stage-induced long noncoding RNAs in the filamentous fungus Fusarium graminearum

Kim, W.; Miguel-Rojas, C.; Wang, J.; Townsend, J. P.; Trail, F.

10.1101/270298 — developmental biology — Posted on 2018-02-23

386 Loss of embryonic neural crest cardiomyocytes causes adult hypertrophic cardiomyopathy

Abdul-Wajid, S.; Demarest, B.; Yost, H. J.

10.1101/270652 — developmental biology — Posted on 2018-02-23

387 Differential Recordings of Local Field Potential: A Genuine Tool to Quantify Functional Connectivity

Comte, J.-C.; Meyer, G.; Carponcy, J.; Salin, P. A.

10.1101/270439 — biophysics — Posted on 2018-02-23

388 Meta-analysis of hypoxic transcriptomes from public databases

Bono, H.

10.1101/267310 — bioinformatics — Posted on 2018-02-23

389 GLUE: A flexible software system for virus sequence data

Singer, J. B.; Thomson, E. C.; McLauchlan, J.; Hughes, J.; Gifford, R. J.

10.1101/269274 — bioinformatics — Posted on 2018-02-23

390 Novel modular pressure and flow rate balanced microfluidic serial dilution networks on printed circuit boards: Designs, Simulations and Fabrication

Vasilakis, N.; Papadimitriou, K. I.; Morgan, H.; Prodromakis, T.

10.1101/270124 — bioengineering — Posted on 2018-02-23

391 Rosetta Antibody Design (RAbD): A General Framework for Computational Antibody Design

Adolf-Bryfogle, J.; Kalyuzhniy, O.; Kubitz, M.; Weitzner, B. D.; Hu, X.; Adachi, Y.; Schief, W. R.; Dunbrack, R. L.

10.1101/183350 — bioengineering — Posted on 2018-02-23

392 Inhibitory and late errors in the antisaccade task: Influence of task design

Aponte, E. A.; Tschan, D. G.; Heinzle, J.; Stephan, K. E.

10.1101/270165 — animal behavior and cognition — Posted on 2018-02-23

393 Soil microbial habitats in an extreme desert Mars-analogue environment

Warren-Rhodes, K.; Lee, K.; Archer, S.; Lacap, D.; Ng-Boyle, L.; Wttergreen, D.; Zacny, K.; Demergasso, C.; Moersch, J.; Chong, G.; Vijayarangan, S.; Thebes, C.; Wagner, M.; Tanaka, K.; Hare, T.; Tate, C.; Wang, A.; Wei, J.; Foil, G.; Cabrol, N.; Pointing, S.

10.1101/269605 — microbiology — Posted on 2018-02-23

394 Parentage assignment with low density array data and low coverage sequence data

Whalen, A.; Gorjanc, G.; Hickey, J.

10.1101/270561 — genetics — Posted on 2018-02-23

395 Quantifying genetic, environmental and individual stochastic variability in Plantago lanceolata

Steiner, U.; Tuljapurkar, S.; Roach, D.

10.1101/270603 — evolutionary biology — Posted on 2018-02-23

396 Evolutionary Rescue Over A Fitness Landscape

Anciaux, Y.; Chevin, L.-M.; Ronce, O.; Martin, G.

10.1101/135780 — evolutionary biology — Posted on 2018-02-23

397 YAP1 Oncogene is a Context-specific Driver for Pancreatic Ductal Adenocarcinoma

Tu, B.; Yao, W.; Yao, J.; Ferri-Borgogno, S.; Chen, S.; Wang, Q.; Yan, L.; Zhu, C.; Bang, S.; Chang, Q.; Bristow, C. A.; Kang, Y.; Zheng, H.; Wang, H.; Fleming, J. B.; Kim, M.; Draetta, G. F.; Pan, D.; Maitra, A.; Gupta, S.; Ying, H.

10.1101/270314 — cancer biology — Posted on 2018-02-23

398 SMuRF: Portable and accurate ensemble-based somatic variant calling

Huang, W.; Guo, Y. A.; Muthukumar, K.; Baruah, P.; Chang, M.; Skanderup, A. J.

10.1101/270413 — bioinformatics — Posted on 2018-02-23

399 Quantitative solid-phase assay to measure deoxynucleoside triphosphate pools

Landoni, J. C.; Wang, L.; Suomalainen, A.

10.1101/270454 — biochemistry — Posted on 2018-02-23

400 CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts

Noe Gonzalez, M.; Sato, S.; Tomomori-Sato, C.; Conaway, J. W.; Conaway, R. C.

10.1101/269977 — molecular biology — Posted on 2018-02-23

401 Bi-clustering interpretation and prediction of correlation between gene expression and protein abundance

Wang, X.; Teng, L.; Zhang, H.; Zhou, Q.; Su, X.; Cui, X.; Bu, D.; Gong, X.; Poetsch, A.; Ning, K.

10.1101/270397 — bioinformatics — Posted on 2018-02-23

402 Amino acid stylization: a new approach for representing protein sequences and scoring protein alignments

Marino, S. M.

10.1101/270488 — bioinformatics — Posted on 2018-02-23

403 A fungal avirulence factor encoded in a highly plastic genomic region triggers partial resistance to septoria tritici blotch

Meile, L.; Croll, D.; Brunner, P. C.; Plissonneau, C.; Hartmann, F. E.; McDonald, B. A.; Sanchez-Vallet, A.

10.1101/264226 — plant biology — Posted on 2018-02-23

404 Network hubs in root-associated fungal metacommunities

Toju, H.; Tanabe, A. S.; Sato, H.

10.1101/270371 — microbiology — Posted on 2018-02-23

405 Factors influencing gene family size variation among related species in a plant family

Wang, P.; Moore, B. M.; Panchy, N. L.; Meng, F.; Lehti-Shiu, M. D.; Shiu, S.-H.

10.1101/270009 — evolutionary biology — Posted on 2018-02-23

406 Muscarinic M1 receptor modulation of synaptic plasticity in nucleus accumbens of wild-type and fragile X mice

Neuhofer, D.; Lassalle, O.; Manzoni, O.

10.1101/270256 — neuroscience — Posted on 2018-02-23

407 nPIST: A Novel Actin Binding Protein of trans-Golgi Network

MAITI, S.; Das, S.; Dutta, P.; mazumder, m.; Seal, S.; Duraivelan, K.; Samanta, D.; Gourinath, s.

10.1101/270363 — cell biology — Posted on 2018-02-23

408 Optimized breath detection algorithm in Electrical Impedance Tomography

Khodadad, D.; Nordebo, S.; Muller, B.; Waldman, A.; Yerworth, R.; Becher, T.; Frerichs, I.; Sophocleos, L.; Van Kaam, A.; Miedema, M.; Seifnaraghi, N.; Bayford, R.

10.1101/270348 — bioengineering — Posted on 2018-02-23

409 Multidirectional digital scanned light-sheet microscopy enables uniform fluorescence excitation and contrast-enhanced imaging

Glaser, A. K.; Chen, Y.; Yin, C.; Wei, L.; Barner, L.; Reder, N.; Liu, J.

10.1101/270207 — bioengineering — Posted on 2018-02-23

410 A novel model for the induction of postnatal murine hip deformity

Killian, M. L.; Atkins, P. R.; Locke, R. C.; James, M. G.; Anderson, A. E.; Clohisy, J. C.

10.1101/270181 — pathology — Posted on 2018-02-22

411 Spinal stretch reflexes exploit musculoskeletal redundancy to support postural hand control

Weiler, J.; Gribble, P. L.; Pruszynski, J. A.

10.1101/270116 — neuroscience — Posted on 2018-02-22

412 Structural diversity across arbuscular mycorrhizal, ectomycorrhizal, and endophytic plant-fungus networks

Toju, H.; Sato, H.; Yamamoto, S.; Tanabe, A. S.

10.1101/269563 — microbiology — Posted on 2018-02-22

413 Identification of general patterns of sex-biased expression in Daphnia, a genus with environmental sex determination

Molinier, C.; Reisser, C.; Fields, P.; Segard, A.; Galimov, Y.; Haag, C. R.

10.1101/269951 — genomics — Posted on 2018-02-22

414 Contact-dependent cell communications drive morphological invariance during ascidian embryogenesis

Guignard, L.; Fiuza, U.-M.; Leggio, B.; Faure, E.; Laussu, J.; Hufnagel, L.; Malandain, G.; Godin, C.; Lemaire, P.

10.1101/238741 — developmental biology — Posted on 2018-02-22

415 Structural Capacitance in Protein Evolution and Human Diseases

Li, C.; Clark, L. V.; Zhang, R.; Porebski, B. T.; McCoey, J. M.; Borg, N. A.; Webb, G. I.; Kass, I.; Buckle, M.; Song, J.; Woolfson, A.; Buckle, A. M.

10.1101/269613 — biochemistry — Posted on 2018-02-22

416 Reaction of Hydrogen sulfide homeostasis genes under biotic and abiotic stress condition in rice -- computational approach

Alagarasan, G.; Ramalingam, J.

10.1101/269639 — plant biology — Posted on 2018-02-22

417 Inhibitory and late errors in the antisaccade task: Influence of task design

Aponte, E. A.; Tschan, D. G.; Heinzle, J.; Stephan, K. E.

10.1101/270165 — neuroscience — Posted on 2018-02-22

418 The development of gut microbiota in ostriches and its association with growth

Videvall, E.; Song, S. J.; Bensch, H. M.; Strandh, M.; Engelbrecht, A.; Serfontein, N.; Hellgren, O.; Olivier, A.; Cloete, S.; Knight, R.; Cornwallis, C. K.

10.1101/270017 — microbiology — Posted on 2018-02-22

419 Isoform-scale annotation and expression profiling of the Cabernet Sauvignon transcriptome using single-molecule sequencing of full-length cDNA

Minio, A.; Massonnet, M.; Vondras, A.; Figueroa-Balderas, R.; Blanco-Ulate, B.; Cantu, D.

10.1101/269530 — genomics — Posted on 2018-02-22

420 Rare germline variants in Fanconi Anemia genes increase risk for squamous lung cancer

Esai Selvan, M.; Klein, R. J.; Gumus, Z.

10.1101/269837 — genomics — Posted on 2018-02-22

421 The relationship between robustness and evolution

Jiang, P.; Kreitman, M.; Reinitz, J.

10.1101/268862 — evolutionary biology — Posted on 2018-02-22

422 Mid-infrared optoacoustic microscopy with label-free chemical contrast in living cells and tissues

Pleitez, M. A.; Khan, A. A.; Reber, J.; Chmyrov, A.; Seeger, M.; Scheideler, M.; Herzig, S.; Ntziachristos, V.

10.1101/270082 — cell biology — Posted on 2018-02-22

423 Utilizing ExAC to Assess the Hidden Contribution of Variants of Unknown Significance to Sanfilippo Type B Incidence

Clark, W. T.; Yu, G. K.; Aoyagi-Scharber, M.; LeBowitz, J. H.

10.1101/253435 — bioinformatics — Posted on 2018-02-22

424 Spinal stretch reflexes exploit musculoskeletal redundancy to support postural hand control

Weiler, J.; Gribble, P. L.; Pruszynski, A.

10.1101/270116 — neuroscience — Posted on 2018-02-22

425 CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts

Noe Gonzalez, M.; Sato, S.; Tomomori-Sato, C.; Conaway, J. W.; Conaway, R. C.

10.1101/269977 — molecular biology — Posted on 2018-02-22

426 Towards comprehensive characterization of CRISPR-linked genes

Shmakov, S. A.; Makarova, K. S.; Wolf, Y. I.; Severinov, K. V.; Koonin, E. V.

10.1101/270033 — genomics — Posted on 2018-02-22

427 Programmable single and multiplex base-editing in Bombyx mori using RNA-guided cytidine deaminases

Xia, Q.; Li, Y.; Ma, S.; Sun, L.; Zhang, T.; Chang, J.; Lu, W.; Chen, X.; Liu, Y.; Wang, X.; Shi, R.; Zhao, P.

10.1101/269969 — genetics — Posted on 2018-02-22

428 The effects of haploid selection on Y chromosome evolution in a dioecious plant

Sandler, G.; Beaudry, F. E. G.; Barrett, S. C. H.; Wright, S. I.

10.1101/264382 — evolutionary biology — Posted on 2018-02-22

429 CRISPR-DT: designing gRNAs for the CRISPR-Cpf1 system with improved target efficiency and specificity

Zhu, H.; Liang, C.

10.1101/269910 — bioinformatics — Posted on 2018-02-22

430 Functional Social Structure in Baboons: Modelling Interactions Between Social and Environmental Structure in Group-Level Foraging

Bonnell, T.; Henzi, P.; Barrett, L.

10.1101/270041 — animal behavior and cognition — Posted on 2018-02-22

431 Genie: An interactive real-time simulation for teaching genetic drift

Castillo, A. I.; Roos, B. H.; Rosenberg, M. S.; Cartwright, R. A.; Wilson Sayres, M. A.

10.1101/268672 — scientific communication and education — Posted on 2018-02-22

432 Long-term depression is independent of GluN2 subunit composition.

Wong, J. M.; Gray, J. A.

10.1101/270074 — neuroscience — Posted on 2018-02-22

433 Secretory vesicle trafficking in awake and anesthetized mice: differential speeds in axons versus synapses

Knabbe, J.; Nassal, J. P.; Verhage, M.; Kuner, T.

10.1101/268078 — neuroscience — Posted on 2018-02-22

434 Learning multiple concurrent higher-order visual sequences in human primary visual cortex

Rosenthal, C. R.; Mallik, I.; Caballero-Gaudes, C.; Sereno, M.; Soto, D.

10.1101/261255 — neuroscience — Posted on 2018-02-22

435 Non-biological synthetic spike-in controls and the AMPtk software pipeline improve mycobiome data

Palmer, J. M.; Jusino, M. A.; Banik, M. T.; Lindner, D. L.

10.1101/213470 — microbiology — Posted on 2018-02-22

436 An Integrin-Independent Kaposi’s Sarcoma-Associated Herpesvirus Infection Mechanism

TerBush, A. A.; Hafkamp, F.; Hartenian, E.; Lee, H. J.; Glaunsinger, B. A.; Coscoy, L.

10.1101/270108 — microbiology — Posted on 2018-02-22

437 Tandem tyrosine residues in the EPEC multicargo chaperone CesT support differential type III effector translocation and early host colonization

Runte, C.; Jain, U.; Getz, L.; Secord, S.; Kuwae, A.; Abe, A.; LeBlanc, J.; Stadnyk, A. W.; Kaper, J. B.; Hansen, A.-M.; Thomas, N. A.

10.1101/270066 — microbiology — Posted on 2018-02-22

438 A hierarchical Bayesian model for detecting convergent rate changes of conserved noncoding elements on phylogenetic trees

Hu, Z.; Sackton, T. B.; Edwards, S. V.; Liu, J. S.

10.1101/260745 — evolutionary biology — Posted on 2018-02-22

439 On the timing of bill length evolution in British great tits: A comment on Bosse et al. 2017.

Perrier, C.; Charmantier, A.

10.1101/269175 — evolutionary biology — Posted on 2018-02-22

440 Oxidative stress in an aged population with diabetes mellitus and/or hypertension

Rodriguez-Castaneda, A.; Martinez-Gonzales, K. L.; Sanchez-Arenas, R.; Sanchez-Garcia, S.; Grijalva, I.; Basurto, L.; Cuadros-Moreno, J.; Ramirez-Garcia, E.; Garcia-delaTorre, P.

10.1101/269993 — epidemiology — Posted on 2018-02-22

441 Tracing the Transitions from Pluripotency to Germ Cell Fate with CRISPR Screening

Hackett, J. A.; Huang, Y.; Gunesdogan, U.; Holm-Gretarsson, K.; Kobayashi, T.; Surani, A. M.

10.1101/269811 — developmental biology — Posted on 2018-02-22

442 Bioscience-scale automated detection of figure element reuse

Acuna, D. E.; Brookes, P. S.; Kording, K. P.

10.1101/269415 — scientific communication and education — Posted on 2018-02-22

443 FERONIA’s sensing of cell wall pectin activates ROP GTPase signaling in Arabidopsis

Lin, W.; Tang, W.; Anderson, C.; Yang, Z.

10.1101/269647 — plant biology — Posted on 2018-02-22

444 Working Memory Load Modulates Neuronal Coupling

Pinotsis, D. A.; Buschman, T. J.; Miller, E. K.

10.1101/192336 — neuroscience — Posted on 2018-02-22

445 Influential parameters for the analysis of intracellular parasite metabolomics

Carey, M. A.; Covelli, V.; Brown, A.; Medlock, G. L.; Haaren, M.; Cooper, J. G.; Papin, J. A.; Guler, J. L.

10.1101/190421 — microbiology — Posted on 2018-02-22

446 Contribution of non-coding mutations to RPGRIP1-mediated inherited retinal degeneration.

Jamshidi, F.; Place, E. M.; Mehrotra, S.; Navarro-Gomez, D.; Maher, M.; Valkanas, E.; Cherry, T. J.; Lek, M.; MacArthur, D.; Bujakowska, K. M.; Pierce, E. A.

10.1101/211292 — genomics — Posted on 2018-02-22

447 A longitudinal model of human neuronal differentiation for functional investigation of schizophrenia polygenic risk

Ori, A. P. S.; Bot, M. H. M.; Molenhuis, R. T.; Olde Loohuis, L. M.; Ophoff, R. A.

10.1101/211581 — genetics — Posted on 2018-02-22

448 A systematic approach for identifying shared mechanisms in epilepsy and its comorbidities

Hoyt, C. T.; Domingo-Fernandez, D.; Balzer (Filep), N. R.; Gueldenpfennig, A.; Hofmann-Apitius, M.

10.1101/269860 — systems biology — Posted on 2018-02-22

449 Bioscience-scale automated detection of figure element reuse

Acuna, D. E.; Brookes, P. S.; Kording, K. P.

10.1101/269415 — scientific communication and education — Posted on 2018-02-22

450 Problematic usage of the Zhang and Luck mixture model

Ma, W. J.

10.1101/268961 — neuroscience — Posted on 2018-02-22

451 Intron-mediated enhancement is not limited to introns

Gallegos, J. E.; Rose, A. B.

10.1101/269852 — molecular biology — Posted on 2018-02-22

452 Survey of human chromosome 21 gene expression effects on early development in Danio rerio

Edie, S.; Zaghloul, N. A.; Leitch, C. C.; Klinedinst, D. K.; Lebron, J.; Thole, J. F.; McCallion, A. S.; Katsanis, N.; Reeves, R. H.

10.1101/269944 — genetics — Posted on 2018-02-22

453 Cellular Migration May Exhibit Intrinsic Left-Right Asymmetries: A meta-analysis

Sullivan, K. G.; Vandenberg, L. N.; Levin, M.

10.1101/269217 — cell biology — Posted on 2018-02-22

454 Separating intrinsic interactions from extrinsic correlations in a network of sensory neurons

Ferrari, U.; Deny, S.; Chalk, M.; Tkacik, G.; Marre, O.; Mora, T.

10.1101/243816 — neuroscience — Posted on 2018-02-22

455 Simultaneous detection of DNA and RNA virus species involved in bovine respiratory disease by PCR-free rapid tagmentation-based library preparation and MinION nanopore sequencing

McCabe, M.; Cormican, P.; Johnston, D.; Earley, B.

10.1101/269936 — molecular biology — Posted on 2018-02-22

456 Quantitative mapping of fluorescently tagged cellular proteins using FCS-calibrated four dimensional imaging

Politi, A. Z.; Cai, Y.; Walther, N.; Hossain, M. J.; Koch, B.; Wachsmuth, M.; Ellenberg, J.

10.1101/188862 — molecular biology — Posted on 2018-02-22

457 So many genes, so little time: a practical approach to divergence-time estimation in the genomic era

Smith, S.; Brown, J. W.; Walker, J. F.

10.1101/114975 — evolutionary biology — Posted on 2018-02-22

458 Contact-dependent cell communications drive morphological invariance during ascidian embryogenesis

Guignard, L.; Fiuza, U.-M.; Leggio, B.; Faure, E.; Laussu, J.; Hufnagel, L.; Malandain, G.; Godin, C.; Lemaire, P.

10.1101/238741 — developmental biology — Posted on 2018-02-22

459 ChromoTrace: Reconstruction of 3D Chromosome Configurations by Super-Resolution Microscopy

Barton, C.; Morganella, S.; Oedegaard, O.; Alexander, S.; Ries, J.; Fitzgerald, T.; Ellenberg, J.; Birney, E.

10.1101/115436 — bioinformatics — Posted on 2018-02-22

460 Partial-Width Injuries of the Rat Rotator Cuff Heal with Fibrosis

Lemmon, E. A.; Locke, R. C.; Szostek, A. K.; Killian, M. L.

10.1101/268920 — bioengineering — Posted on 2018-02-22

461 Reading Profiles in Multi-site Data with Missingness

Eckert, M.; Vaden, K.; Gebregziabher, M.; Dyslexia Data Consortium,

10.1101/269555 — neuroscience — Posted on 2018-02-22

462 The pharmacological perturbation of brain zinc impairs BDNF-related signalling and the cognitive performances of young mice

Frazzini, V.; Granzotto, A.; Bomba, M.; Massetti, N.; Castelli, V.; d'Aurora, M.; Punzi, M.; Iorio, M.; Mosca, A.; Delli Pizzi, S.; Gatta, V.; Cimini, A.; Sensi, S. L.

10.1101/267609 — neuroscience — Posted on 2018-02-22

463 Distinct co-modulation rules of synaptic and voltage-gated currents coordinates interactions of multiple neuromodulators

Li, X.; Bucher, D. M.; Nadim, F.

10.1101/265694 — neuroscience — Posted on 2018-02-22

464 Learning to read increases the informativeness of distributed ventral temporal responses

Nordt, M.; Gomez, J.; Natu, V.; Jeska, B.; Barnett, M.; Grill-Spector, K.

10.1101/257055 — neuroscience — Posted on 2018-02-22

465 Genetic meta-analysis identifies 9 novel loci and functional pathways for Alzheimers disease risk

Jansen, I.; Savage, J.; Watanabe, K.; Bryois, J.; Williams, D.; Steinberg, S.; Sealock, J.; Karlsson, I.; Hagg, S.; Athanasiu, L.; Voyle, N.; Proitsi, P.; Witoelar, A.; Stringer, S.; Aarsland, D.; Almdahl, I.; Andersen, F.; Bergh, S.; Bettella, F.; Bjornsson, S.; Braekhus, A.; Brathen, G.; de Leeuw, C.; Desikan, R.; Djurovic, S.; Dumitrescu, L.; Fladby, T.; Homan, T.; Jonsson, P.; Kiddle, S.; Rongve, A.; Saltvedt, I.; Sando, S.; Selbak, G.; Skene, N.; Snaedal, J.; Stordal, E.; Ulstein, I.; Wang, Y.; White, L.; Hjerling-Leffler, J.; Sullivan, P.; van der Flier, W.; Dobson, R.; Davis, L.; Stefan

10.1101/258533 — genetics — Posted on 2018-02-22

466 A hierarchical Bayesian model for detecting convergent rate changes of conserved noncoding elements on phylogenetic trees

Hu, Z.; Sackton, T. B.; Edwards, S. V.; Liu, J. S.

10.1101/260745 — evolutionary biology — Posted on 2018-02-22

467 Dissecting Conformational Changes in APP’s Transmembrane Domain Linked to ε-Efficiency in Familial Alzheimer’s Disease

Goetz, A.; Scharnagl, C.

10.1101/269084 — biophysics — Posted on 2018-02-22

468 MetaMap: An atlas of metatranscriptomic reads in human disease-related RNA-seq data

Simon, L. M.; Karg, S.; Westermann, A. J.; Engel, M.; Elbehery, A. H.; Hense, B.; Heinig, M.; Deng, L.; Theis, F. J.

10.1101/269092 — bioinformatics — Posted on 2018-02-22

469 Genie: An interactive real-time simulation for teaching genetic drift

Castillo, A. I.; Ross, B. H.; Rosenberg, M. S.; Cartwright, R. A.; Wilson Sayres, M. A.

10.1101/268672 — scientific communication and education — Posted on 2018-02-22

470 White matter plasticity and reading instruction: Widespread anatomical changes track the learning process

Huber, E.; Donnelly, P. M.; Rokem, A.; Yeatman, J.

10.1101/268979 — neuroscience — Posted on 2018-02-22

471 Evidence for functional and non-functional classes of peptides translated from long non-coding RNAs

Ruiz-Orera, J.; Verdaguer-Grau, P.; Villanueva-Canas, J. L.; Messeguer, X.; Alba, M. M.

10.1101/064915 — evolutionary biology — Posted on 2018-02-22

472 AlignmentViewer: Sequence Analysis of Large Protein Families

Reguant, R.; Antipin, Y.; Sheridan, R.; Luna, A.; Sander, C.

10.1101/269720 — bioinformatics — Posted on 2018-02-22

473 Leg force interference in poly-pedal locomotion

Weihmann, T.

10.1101/269100 — zoology — Posted on 2018-02-22

474 Controlling insulin resistance through modulation of interplay between mediators of cellular senescence: A mathematical study

Arora, C.; Nizami, H. L.; Chatterjee, S.

10.1101/269738 — systems biology — Posted on 2018-02-22

475 The application of text mining algorithms in summarizing trends in anti-epileptic drug research

Singh, S. P.; Karkare, S.; Baswan, S. M.; Singh, V. P.

10.1101/269308 — systems biology — Posted on 2018-02-22

476 Using confidence inferred from pupil-size to dissect perceptual task-strategy: support for a bounded decision-formation process

Kawaguchi, K.; Clery, S.; Pourriahi, P.; Seillier, L.; Haefner, R.; Nienborg, H.

10.1101/269159 — neuroscience — Posted on 2018-02-22

477 A sub-movement time scale of human motor adaptation

Crevecoeur, F.; Thonanrd, J.-L.; Lefevre, P.

10.1101/269134 — neuroscience — Posted on 2018-02-22

478 The timing of hemodynamic changes reliably reflects spiking activity

Zaidi, A. D.; Birbaumer, N.; Fetz, E.; Logothetis, N.; SItaram, R.

10.1101/269696 — neuroscience — Posted on 2018-02-22

479 Semaphorin4D induces inhibitory synapse formation by rapid stabilization of presynaptic boutons via MET co-activation

Frias, C. P.; Bresser, T.; Scheefhals, L.; Hu, H. Y.; van Bergen en Henegouwen, P. M. P.; Hoogenraad, C. C.; Wierenga, C. J.

10.1101/100271 — neuroscience — Posted on 2018-02-22

480 Emergence of oscillations via spike timing dependent plasticity

Soloduchin, S.; Shamir, M.

10.1101/269712 — neuroscience — Posted on 2018-02-22

481 An Augmented Aging Process in Brain White Matter in HIV

Kuhn, T.; Kaufmann, T.; Doan, N. T.; Westlye, L. T.; Jones, J. D.; Nunez, R. A.; Bookheimer, S. Y.; Singer, E. J.; Hinkin, C. H.; Thames, A. D.

10.1101/265199 — neuroscience — Posted on 2018-02-22

482 Dissociable contributions of the amygdala to the immediate and delayed effects of emotional arousal on memory

Schuemann, D.; Sommer, T.

10.1101/269050 — neuroscience — Posted on 2018-02-22

483 Sound induces change in orientation preference of V1 neurons: Audio-visual cross-influence

Chanauria, N.; Bharmauria, V.; Bachatene, L.; Cattan, S.; Rouat, J.; Molotchnikoff, S.

10.1101/269589 — neuroscience — Posted on 2018-02-22

484 Comparing EEG/MEG neuroimaging methods based on localization error, false positive activity, and false positive connectivity

Pascual-Marqui, R. D.; Faber, P. L.; Kinoshita, T.; Kochi, K.; Milz, P.; Nishida, K.; Yoshimura, M.

10.1101/269753 — neuroscience — Posted on 2018-02-22

485 Selective and context-dependent social and behavioral effects of Δ9-tetrahydrocannabinol in weakly electric fish

Neeley, B.; Overholt, T.; Artz, E.; Kinsey, S. G.; Marsat, G.

10.1101/269803 — neuroscience — Posted on 2018-02-22

486 Influenza A virus environmental persistence is driven by the hemagglutinin and the neuraminidase

Labadie, T.; Batejat, C.; Manuguerra, J.-C.; Leclercq, I.

10.1101/268722 — microbiology — Posted on 2018-02-22

487 Streptococcal Lancefield polysaccharides are critical cell wall determinants for human group IIA secreted phospholipase A2 to exert its bactericidal effects

van Hensbergen, V. P.; Movert, E.; de Maat, V.; Le Breton, Y.; Lambeau, G.; Payre, C.; Kahn, F.; Henningham, A.; Nizet, V.; Van Strijp, J. A. G.; Carlsson, F.; McIver, K. S.; van Sorge, N. M.

10.1101/269779 — microbiology — Posted on 2018-02-22

488 A semi-lethal CRISPR-Cas system permits DNA acquisition in Enterococcus faecalis

Hullahalli, K.; Rodrigues, M.; Nguyen, U.; Palmer, K.

10.1101/232322 — microbiology — Posted on 2018-02-22

489 Experimental and mathematical approaches to quantify recirculation kinetics of lymphocytes

Ganusov, V. V.; Tomura, M.

10.1101/268326 — immunology — Posted on 2018-02-22

490 A pseudogene of caffeic acid-o-methyltransferase (COMT) in Acacia mangium: Comparative analysis with other COMT plant promoters

Abdul Latif, A.; Tam, S. M.; Ratnam, W.

10.1101/269654 — genetics — Posted on 2018-02-22

491 Haploid selection, sex ratio bias, and transitions between sex-determining systems

Scott, M. F.; Osmond, M. M.; Otto, S. P.

10.1101/269431 — evolutionary biology — Posted on 2018-02-22

492 RAD sequencing and a hybrid Antarctic fur seal genome assembly reveal rapidly decaying linkage disequilibrium, global population structure and evidence for inbreeding

Humble, E.; Dasmahapatra, K. K.; Martinez-Barrio, A.; Gregorio, I.; Forcada, J.; Polikeit, A.-C.; Goldsworthy, S. D.; Goebel, M. E.; Kalinowski, J.; Wolf, J.; Hoffman, J.

10.1101/269167 — evolutionary biology — Posted on 2018-02-22

493 SOX2 Regulation by Hedgehog Signaling Controls Adult Lingual Epithelium Homeostasis

Castillo-Azofeifa, D.; Seidel, K.; Gross, L.; Jacquez, B.; Klein, O. D.; Barlow, L. A.

10.1101/269522 — developmental biology — Posted on 2018-02-22

494 ADAR1 A-to-I RNA editing alters codon usage

Brachova, P.; Alvarez, N. S.; Hong, X.; Vincent, K. A.; Latham, K. E.; Christenson, L. K.

10.1101/268813 — developmental biology — Posted on 2018-02-22

495 High affinity interactions and signal transduction between Aβ oligomers and TREM2

Lessard, C. B.; Malnik, S. L.; Zhou, Y.; Ladd, T. B.; Cruz, P. E.; Ran, Y.; Chakrabaty, P.; Mahan, T. E.; Holtzman, D. M.; Ulrich, J. D.; Colonna, M.; Golde, T.

10.1101/269787 — cell biology — Posted on 2018-02-22

496 Hematopoietic Stem And Progenitor Cells Use Podosomes To Transcellularly Home To The Bone Marrow.

Rademakers, T.; Goedhart, M.; Hoogenboezem, M.; Garcia Ponce, A.; van Rijssel, J.; Samus, M.; Schnoor, M.; Butz, S.; Huveneers, S.; Vestweber, D.; Nolte, M. A.; Voermans, C.; van Buul, J. D.

10.1101/269704 — cell biology — Posted on 2018-02-22

497 PAGE4 and Conformational Switching: Insights from Molecular Dynamics Simulations and Implications for Prostate Cancer

Lin, X.; Roy, S.; Jolly, M. K.; Bocci, F.; Schafer, N.; Tsai, M.-Y.; Chen, Y.; He, Y.; Grishaev, A.; Weninger, K.; Orban, J.; Kulkarni, P.; Rangarajan, G.; Levine, H.; Onuchic, J. N.

10.1101/264010 — biophysics — Posted on 2018-02-22

498 Information transfer in QT-RR dynamics: Towards a model-free QT correction method

Potapov, I.; Latukka, J.; Kim, J.; Luukko, P.; Aalto-Setälä, K.; Räsänen, E.

10.1101/269670 — biophysics — Posted on 2018-02-22

499 eTumorMetastasis, a network-based algorithm predicts clinical outcomes using whole-exome sequencing data of cancer patients

Milanese, J.-S.; Tibiche, C.; Zaman, N.; Zou, J.; Han, P.; Meng, Z.; Nantel, A.; Droit, A.; Wang, E.

10.1101/268680 — bioinformatics — Posted on 2018-02-22

500 ChIPSeqSpike: A R/Bioconductor package for ChIP-Seq data scaling according to spike-in control

Descostes, N.; Tsirigos, A.; Reinberg, D.

10.1101/269118 — bioinformatics — Posted on 2018-02-22

501 hRBPome: a central repository of all known human RNA-binding proteins

Ghosh, P.; Murugavel, P.; Sowdhamini, R.

10.1101/269043 — bioinformatics — Posted on 2018-02-22

502 Functional equivalence of genome sequencing analysis pipelines enables harmonized variant calling across human genetics projects

Regier, A. A.; Farjoun, Y.; Larson, D.; Krasheninina, O.; Kang, H. M.; Howrigan, D. P.; Chen, B.-J.; Kher, M.; Banks, E.; Ames, D. C.; English, A. C.; Li, H.; The NHLBI Trans-Omics for Precision Medicine (TOPMed) Program, ; Abecasis, G. R.; Salerno, W.; Zody, M. C.; Neale, B. M.; Hall, I. M.

10.1101/269316 — bioinformatics — Posted on 2018-02-22

503 Principal component based adaptive association test of multiple traits using GWAS summary statistics

Guo, B.; WU, B.

10.1101/269597 — bioinformatics — Posted on 2018-02-22

504 EcRBPome: a comprehensive database of all known E. coli RNA-binding proteins

Ghosh, P.; Guita, N.; Offmann, B.; Sowdhamini, R.

10.1101/268441 — bioinformatics — Posted on 2018-02-22

505 Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells

Tycko, J.; Barrera, L. A.; Huston, N.; Friedland, A. E.; Wu, X.; Gootenberg, J. S.; Abudayyeh, O. O.; Myer, V. E.; Wilson, C. J.; Hsu, P. D.

10.1101/269399 — bioengineering — Posted on 2018-02-22

506 Structural Capacitance in Protein Evolution and Human Diseases

Li, C.; Clarke, L. V.; Zhang, R.; Porebski, B. T.; McCoey, J.; Borg, N.; Webb, G.; Kass, I.; Buckle, M.; Song, J.; Woolfson, A.; Buckle, A.

10.1101/269613 — biochemistry — Posted on 2018-02-22

507 Clinical assay for direct assessment of IgG galactosylation in serum using endoglycosidase S

Vanderschaeghe, D.; Meuris, L.; Grootaert, H.; Raes, T.; Van Hecke, A.; Verhelst, X.; Van de Velde, F.; Lapauw, B.; Van Vlierberghe, H.; Callewaert, N.

10.1101/269795 — biochemistry — Posted on 2018-02-22

508 Value-based decisions involve sequential sampling from memory

Bakkour, A.; Zylberberg, A.; Shadlen, M. N.; Shohamy, D.

10.1101/269290 — animal behavior and cognition — Posted on 2018-02-22

509 Adaptive planning in human search

Krusche, M. J. F.; Schulz, E.; Guez, A.; Speekenbrink, M.

10.1101/268938 — animal behavior and cognition — Posted on 2018-02-22

510 FERONIA’s sensing of cell wall pectin activates ROP GTPase signaling in Arabidopsis

Yang, Z.; Lin, W.; Tang, W.; Anderson, C.

10.1101/269647 — plant biology — Posted on 2018-02-22

511 Structural diversity across arbuscular mycorrhizal, ectomycorrhizal, and endophytic plant-fungus networks

Toju, H.; Sato, H.; Yamamoto, S.; Tanabe, A. S.

10.1101/269563 — microbiology — Posted on 2018-02-22

512 Tripsacum de novo transcriptome assemblies reveal parallel gene evolution with maize after ancient polyploidy

Gault, C.; Kremling, K.; Buckler, E. S.

10.1101/267682 — genomics — Posted on 2018-02-22

513 Genomes of all known members of a Plasmodium subgenus reveal paths to virulent human malaria

Otto, T. D.; Gilabert, A.; Crellen, T.; Böhme, U.; Arnathau, C.; Sanders, M.; Oyola, S.; Okauga, A. P.; Boundenga, L.; Wuillaume, E.; Ngoubangoye, B.; Moukodoum, N.; Paupy, C.; Durand, P.; Rougeron, V.; Ollomo, B.; Renaud, F.; Newbold, C.; Berriman, M.; Prugnolle, F.

10.1101/095679 — evolutionary biology — Posted on 2018-02-22

514 Do latitudinal gradients exist in New Zealand stream invertebrate metacommunities?

Tonkin, J. D.; Death, R. G.; Muotka, T.; Astorga, A.; Lytle, D. A.

10.1101/084673 — ecology — Posted on 2018-02-22

515 Epigenetic Profiling for the Molecular Classification of Metastatic Brain Tumors

Orozco, J. I. J.; Knijnenburg, T. A.; Manughian-Peter, A. O.; Salomon, M. P.; Barkhoudarian, G.; Jalas, J. R.; Wilmott, J. S.; Hothi, P.; Wang, X.; Takasumi, Y.; Buckland, M. E.; Thompson, J. F.; Long, G. V.; Cobbs, C. S.; Shmulevich, I.; Kelly, D. F.; Scolyer, R. A.; Hoon, D. S. B.; Marzese, D. M.

10.1101/268193 — cancer biology — Posted on 2018-02-22

516 GLUE: A flexible software system for virus sequence data

Singer, J. B.; Thomson, E. C.; McLauchlan, J.; Hughes, J.; Gifford, R. J.

10.1101/269274 — bioinformatics — Posted on 2018-02-22

517 The Pseudomonas aeruginosa LasR quorum-sensing receptor balances ligand selectivity and sensitivity

Bassler, B. L.; McCready, A. R.; Paczkowski, J. E.; Henke, B. R.

10.1101/269001 — microbiology — Posted on 2018-02-21

518 Citius, Fortius? Cohort, inflammation and trajectories of gait speed and grip strength in older Britons

Tampubolon, G.; Fajarini, M.

10.1101/268334 — epidemiology — Posted on 2018-02-21

519 Ability of known susceptibility SNPs to predict colorectal cancer risk for persons with and without a family history

Jenkins, M.; Win, A. K.; Dowty, J.; MacInnis, R.; Makalic, E.; Schmidt, D.; Dite, G.; Kapuscinski, M.; Clendenning, M.; Rosty, C.; Winship, I.; Emery, J.; Saya, S.; Macrae, F.; Ahnen, D.; Duggan, D.; Figueiredo, J.; Lindor, N.; Haile, R.; Potter, J.; Cotterchio, M.; Gallinger, S.; Newcomb, P.; Buchanan, D.; Casey, G.; Hopper, J.

10.1101/267666 — epidemiology — Posted on 2018-02-21

520 MicroRNA-132 provides neuroprotection for tauopathies via multiple signaling pathways

EL Fatimy, R.; Li, S.; Chen, Z.; Mushannen, T.; Gongala, S.; Wei, Z.; Balu, D. T.; Rabinovsky, R.; Cantlon, A.; Elkhal, A.; Selkoe, D. J.; Sonntag, K. C.; Walsh, D. M.; Krichevsky, A. M.

10.1101/258509 — neuroscience — Posted on 2018-02-21

521 Rifampicin or capreomycin induced remodelling of the Mycobacterium smegmatis mycolic acid layer is mitigated in synergistic combinations with cationic antimicrobial peptides

Man, D. K.-W.; Kanno, T.; Manzo, G.; Robertson, B. D.; Lam, J. K.; Mason, A. J.

10.1101/269324 — microbiology — Posted on 2018-02-21

522 Meta-analysis reveals host-dependent nitrogen recycling as a mechanism of symbiont control in Aiptasia

Cui, G.; Liew, Y. J.; Li, Y.; Kharbatia, N.; Zahran, N. I.; Emwas, A.-H.; Eguiluz, V. M.; Aranda Lastra, M.

10.1101/269183 — genomics — Posted on 2018-02-21

523 RNA-Seq in 296 phased trios provides a high resolution map of genomic imprinting

Jadhav, B; Monajemi, R; Gagalova, K; Draisma, H; van de Wiel, M; Franke, L; Heijmans, B; van Meurs, J; Jansen, R; ʼt Hoen, P; Sharp, A; Kiełbasa, S

10.1101/269449 — genomics — Posted on 2018-02-21

524 Vps74 connects the Golgi apparatus and telomeres in Saccharomyces cerevisiae

Lydall, D.; Rodrigues, J.; Banks, P.

10.1101/269456 — genetics — Posted on 2018-02-21

525 Insights into the evolution of extracellular leucine rich repeats in metazoans with special reference to Toll-like receptor 4

Dhar, D.; Dey, D.; Basu, S.

10.1101/269241 — bioinformatics — Posted on 2018-02-21

526 ViDGER: An R package for integrative interpretation of differential gene expression results of RNA-seq data

McDermaid, A.; Monier, B.; Zhao, J.; Ma, Q.

10.1101/268896 — bioinformatics — Posted on 2018-02-21

527 Cytokinin perception in potato: New features of canonic players

Lomin, S. N.; Myakushina, Y. A.; Kolachevskaya, O. O.; Getman, I. A.; Arkhipov, D. V.; Savelieva, E. M.; Osolodkin, D. I.; Romanov, G. A.

10.1101/269266 — plant biology — Posted on 2018-02-21

528 Extracellular Pax6 regulates tangential Cajal-Retzius cell migration

Kaddour, H.; Coppola, E.; Di Nardo, A.; Wizenmann, A.; Volovitch, M.; Prochiantz, A.; Pierani, A.

10.1101/269480 — neuroscience — Posted on 2018-02-21

529 Probing host-anaerobe interactions in innovative human gut cellular models

Anonye, B. O.; Hassall, J.; Patient, J.; Detamornrat, U.; Aladdad, A. M.; Schüller, S.; Rose, F. R. A. J.; Unnikrishnan, M.

10.1101/269035 — microbiology — Posted on 2018-02-21

530 Cell type-dependent control of p53 transcription and enhancer activity by p63

Karsli Uzunbas, G.; Ahmed, F.; Sammons, M. A.

10.1101/268649 — genomics — Posted on 2018-02-21

531 Intergenerational epigenetic inheritance in reef-building corals

Liew, Y. J.; Howells, E. J.; Wang, X.; Michell, C. T.; Burt, J. A.; Idaghdour, Y.; Aranda, M.

10.1101/269076 — genetics — Posted on 2018-02-21

532 Predicting The Effects Of Hemlock Woolly Adelgid On Microhabitat Structure And Small Mammal Communities

Degrassi, A.

10.1101/269142 — ecology — Posted on 2018-02-21

533 Adaptive diversification of growth allometry in the plant Arabidopsis thaliana

Vasseur, F.; Exposito-Alonso, M.; Ayala-Garay, O. J.; Wang, G.; Enquist, B. J.; Vile, D.; Violle, C.; Weigel, D.

10.1101/269498 — ecology — Posted on 2018-02-21

534 Image-based methods for phenotyping growth dynamics and fitness in Arabidopsis thaliana

Vasseur, F.; Wang, G.; Bresson, J.; Schwab, R.; Weigel, D.

10.1101/208512 — bioinformatics — Posted on 2018-02-21

535 SMARTcleaner: identify and clean off-target signals in SMART ChIP-seq analysis

Zhao, D.; Zheng, D.

10.1101/269365 — bioinformatics — Posted on 2018-02-21

536 Standard operating procedure for somatic variant refinement of tumor sequencing data

Barnell, E. K.; Ronning, P.; Campbell, K. M.; Krysiak, K.; Ainscough, B. J.; Ramirez, C.; Spies, N.; Kunisaki, J.; Hundal, J.; Skidmore, Z. L.; Gomez, F.; Trani, L.; Matlock, M.; Wagner, A. H.; Swamidass, S. J.; Griffith, M.; Griffith, O. L.

10.1101/266262 — genetics — Posted on 2018-02-21

537 Expanding the genetic toolkit of Tribolium castaneum

Rylee, J. C.; Siniard, D. J.; Doucette, K.; Zentner, G. E.; Zelhof, A.

10.1101/269464 — genetics — Posted on 2018-02-21

538 Rapid proteotyping reveals cancer biology and drug response determinants in the NCI-60 cells

Guo, T.; Luna, A.; Koh, C. C.; Rajapakse, V.; Wu, Z.; Menden, M. P.; Cheng, Y.; Calzone, L.; Martignetti, L.; Ori, A.; Iskar, M.; Gillet, L.; Zhong, Q.; Varma, S.; Schmitt, U.; Qiu, P.; Sun, Y.; zhu, Y.; Wild, P.; Mathew, G.; Bork, P.; Beck, M.; Saez-Rodriguez, J.; Reinhold, W.; Sander, C.; Pommier, Y.; Aebersold, R.

10.1101/268953 — systems biology — Posted on 2018-02-21

539 Social licence through citizen science: A tool for marine conservation

Kelly, R.; Fleming, A.; Pecl, G.; Richter, A.; Bonn, A.

10.1101/266692 — scientific communication and education — Posted on 2018-02-21

540 Light Pollution Increases West Nile Virus Competence in a Ubiquitous Passerine Reservoir Species

Kernbach, M. E.; Miller, J. M.; Hall, R. J.; Unnasch, T. R.; Burkett-Cadena, N. D.; Martin, L. B.

10.1101/269209 — pathology — Posted on 2018-02-21

541 Working Memory Load Modulates Neuronal Coupling

Pinotsis, D. A.; Buschman, T. J.; Miller, E. K.

10.1101/192336 — neuroscience — Posted on 2018-02-21

542 Trends in CRP, D-dimer and fibrinogen during therapy for HIV associated multidrug resistant tuberculosis

Cudahy, P. G. T.; Warren, J. L.; Cohen, T.; Wilson, D.

10.1101/268367 — immunology — Posted on 2018-02-21

543 Optimizing conservation of migratory species over their full annual cycle in the Western Hemisphere

Schuster, R.; Wilson, S.; Rodewald, A.; Arcese, P.; Fink, D.; Auer, T.; Bennett, J.

10.1101/268805 — ecology — Posted on 2018-02-21

544 Ubiquitous abundance distribution of non-dominant plankton across the world’s ocean

Ser-Giacomi, E.; Zinger, L.; Malviya, S.; De Vargas, C.; Karsenti, E.; Bowler, C.; De Monte, S.

10.1101/269068 — ecology — Posted on 2018-02-21

545 ADAR1 A-to-I RNA alters codon usage

Brachova, P.; Alvarez, N. S.; Hong, X.; Vincent, K. A.; Latham, K. E.; Christenson, L. K.

10.1101/268813 — developmental biology — Posted on 2018-02-21

546 Phosphatidylethanolamine produced in the inner mitochondrial membrane is essential for yeast cytochrome bc1 complex function

Calzada, E.; Claypool, S.

10.1101/269233 — cell biology — Posted on 2018-02-21

547 Bead Enhancement of EV Analysis

Lin, H.-Y.; Yang, K. S.; Curley, C.; Lee, H.; Welch, M. W.; Wolpin, B. M.; Weissleder, R.; Im, H.; Castro, C.

10.1101/269423 — cancer biology — Posted on 2018-02-21

548 Structure of APP-C991-99 and Implications for Role of Extra-Membrane Domains in Function and Oligomerization

Pantelopulos, G. A.; Straub, J. E.; Thirumalai, D.; Sugita, Y.

10.1101/257469 — biophysics — Posted on 2018-02-21

549 Dissecting Conformational Changes in APP’s Transmembrane Domain Linked to Altered ε-Efficiency of Familial Alzheimer’s Disease Mutants

Goetz, A.; Scharnagl, C.

10.1101/269084 — biophysics — Posted on 2018-02-21

550 SeqStruct : A New Amino Acid Similarity Matrix Based on Sequence Correlations and Structural Contacts Yields Sequence-Structure Congruence

Jia, K.; Jernigan, R. L.

10.1101/268904 — bioinformatics — Posted on 2018-02-21

551 An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness

Galarza Torre, A.; Shaw, J. E.; Wood, A.; Gilbert, H. T. J.; Dobre, O.; Genever, P.; Brennan, K.; Richardson, S. M.; Swift, J.

10.1101/269225 — bioengineering — Posted on 2018-02-21

552 Multimodal on-axis platform for all-optical electrophysiology with near-infrared probes in human stem-cell-derived cardiomyocytes

Klimas, A.; Ortiz, G.; Boggess, S.; Miller, E. W.; Entcheva, E.

10.1101/269258 — bioengineering — Posted on 2018-02-21

553 Real-time tracking of complex ubiquitination cascades using a fluorescent confocal on-bead assay

Koszela, J.; Pham, N.; Evans, D.; Mann, S.; Perez-Pi, I.; Shave, S.; Ceccarelli, D.; Sicheri, F.; Tyers, M.; Auer, M.

10.1101/268706 — biochemistry — Posted on 2018-02-21

554 Spacing of Cue-approach Training Leads to Better Maintenance of Behavioral Change

Bakkour, A.; Botvinik Nezer, R.; Cohen, N.; Hover, A. M.; Poldrack, R. A.; Schonberg, T.

10.1101/268821 — animal behavior and cognition — Posted on 2018-02-21

555 meaRtools: an R package for the Comprehensive Analysis of Neuronal Networks Recorded on Multi-Electrode Arrays

10.1101/242065 — neuroscience — Posted on 2018-02-21

556 Viromic analysis of wastewater input to a river catchment reveals a diverse assemblage of RNA viruses

Adriaenssens, E.; Farkas, K.; Harrison, C.; Jones, D.; Allison, H. E.; McCarthy, A. J.

10.1101/248203 — microbiology — Posted on 2018-02-21

557 A fine-tuned vector-parasite dialogue in tsetse’s cardia determines peritrophic matrix integrity and trypanosome transmission success

Vigneron, A.; Aksoy, E.; Weiss, B. L.; Bing, X.; Zhao, X.; Awuoche, E. O.; O'Neill, M.; Wu, Y.; Attardo, G. M.; Aksoy, S.

10.1101/207993 — microbiology — Posted on 2018-02-21

558 Neuronal receptors display cytoskeleton-independent directed motion on the plasma membrane

Taylor, R. D.; Heine, M.; Emptage, N. J.; Andreae, L.

10.1101/269381 — cell biology — Posted on 2018-02-21

559 Phospho-signal flow from a pole-localized microdomain spatially patterns transcription factor activity

Lasker, K.; von Diezmann, A.; Ahrens, D. G.; Mann, T. H.; Moerner, W. E.; Shapiro, L.

10.1101/220293 — cell biology — Posted on 2018-02-21

560 TreeCluster: Massively scalable transmission clustering using phylogenetic trees

Moshiri, A. N.

10.1101/261354 — bioinformatics — Posted on 2018-02-21

561 Linear models enable powerful differential activity analysis in massively parallel reporter assays

Myint, L.; Avramopoulos, D. G.; Goff, L. A.; Hansen, K. D.

10.1101/196394 — bioinformatics — Posted on 2018-02-21

562 Tectal stem cells display diverse regenerative capacities

Lindsey, B. W.; Aitken, G. E.; Tang, J. K.; Khabooshan, M.; Vandestadt, C.; Kaslin, J.

10.1101/268136 — neuroscience — Posted on 2018-02-21

563 Topology highlights mesoscopic functional equivalence between imagery and perception

Ibanez-Marcelo, E.; Campioni, L.; Phinyomark, A.; Petri, G.; Santarcangelo, E. L.

10.1101/268383 — neuroscience — Posted on 2018-02-21

564 Cognitive Changes associated with Alzheimer’s disease in Down syndrome

Firth, N. C.; Startin, C. M.; Hithersay, R.; Hamburg, S.; Wijeratne, P. A.; Mok, K. Y.; Hardy, J.; Alexander, D. C.; The LonDownS Consortium, ; Strydom, A.

10.1101/263095 — neuroscience — Posted on 2018-02-21

565 Cell surface vimentin is involved in matrix stiffness-dependent infection of endothelial cells by Listeria monocytogenes

Bastounis, E. E.; Yeh, Y.-T.; Theriot, J. A.

10.1101/198739 — microbiology — Posted on 2018-02-21

566 Previously Hidden Dynamics at the TCR-pMHC Interface Revealed

Fodor, J.; Riley, B. T.; Borg, N. A.; Buckle, A. M.

10.1101/223628 — immunology — Posted on 2018-02-21

567 Genetic risk for schizophrenia influences substance use in emerging adulthood: An event-level polygenic prediction model

Mallard, T. T.; Harden, K. P.; Fromme, K.

10.1101/157636 — genetics — Posted on 2018-02-21

568 Association between the brain-derived neurotrophic factor Val66Met polymorphism and overweight/obesity in Mexican pediatric population

Martinez-Ezquerro, J. D.; Rendon-Macias, M. E.; Zamora-Mendoza, G.; Serrano-Meneses, J.; Rosales-Rodriguez, B.; Escalante-Bautista, D.; Rodriguez-Cruz, M.; Sanchez Gonzalez, R.; Arellano-Pineda, Y.; Lopez-Alarcon, M.; Zampedri, M. C.; Rosas-Vargas, H.

10.1101/215798 — genetics — Posted on 2018-02-21

569 Dual-layer transposon repression in heads of Drosophila melanogaster

van den Beek, M.; da Silva, B.; Pouch, J.; Ali Chaouche, M. e. a.; Carre, C.; Antoniewski, C.

10.1101/267039 — genetics — Posted on 2018-02-21

570 A complex performance landscape for suction-feeding reveals constraints and adaptations in a population of reef damselfish

Keren, T.; Kiflawi, M.; Martin, C.; China, V.; Mann, O.; Holzman, R.

10.1101/239418 — evolutionary biology — Posted on 2018-02-21

571 MARGE: Mutation Analysis for Regulatory Genomic Elements

Link, V. M.; Romanoski, C. E.; Metzler, D.; Glass, C. K.

10.1101/268839 — bioinformatics — Posted on 2018-02-21

572 Common variants in ABCG8 and TRAF3 genes confer risk for gallstone disease and gallbladder cancer in admixed Latinos with Mapuche Native American ancestry

Bustos, B. I.; Perez-Palma, E.; Buch, S.; Azocar, L.; Riveras, E.; Ugarte, G. D.; Toliat, M.; Nuernberg, P.; Lieb, W.; Franke, A.; Hinz, S.; Burmeister, G.; von Schoenfels, W.; Schafmayer, C.; Voelzke, H.; Voelker, U.; Homuth, G.; Lerch, M. M.; Santos, J. L.; Puschel, K.; Bambs, C.; Gutierrez, R. A.; Hampe, J.; De Ferrari, G. V.; Miquel, J. F.

10.1101/265728 — genetics — Posted on 2018-02-21

573 Aurora B-mediated exclusion of HP1a from late-segregating chromatin prevents formation of micronuclei

Warecki, B.; Sullivan, W.

10.1101/268912 — cell biology — Posted on 2018-02-21

574 Endothelia extrude apoptotic cells to maintain a constant barrier

Mleynek, T.; Li, D.; Rosenblatt, J.; Redd, M. J.; Chan, A.; Gu, Y.

10.1101/268946 — cell biology — Posted on 2018-02-21

575 Targeting TrkB with a brain-derived neurotrophic factor mimetic promotes myelin repair in the brain

Fletcher, J. L.; Wood, R. J.; Nguyen, J.; Normon, E. M.; Jun, C. M.; Prawdiuk, A. R.; Biemond, M.; Nguyen, H. T.; Northfield, S. E.; Hughes, R. A.; Gonsalvez, D. G.; Xiao, J.; Murray, S. S.

10.1101/268300 — neuroscience — Posted on 2018-02-20

576 Dual-layer transposon repression in heads of Drosophila melanogaster

van den Beek, M.; da Silva, B.; Pouch, J.; Ali Chaouche, M. e. a.; Carre, C.; Antoniewski, C.

10.1101/267039 — genetics — Posted on 2018-02-20

577 Identification and Structure-Activity Relationship of HDAC6 Zinc-finger Ubiquitin Binding Domain Inhibitors

Ferreira de Freitas, R.; Harding, R.; Franzoni, I.; Ravichandran, M.; Mann, M. K.; Ouyang, H.; Lautens, M.; Santhakumar, V.; Arrowsmith, C.; Schapira, M.

10.1101/268557 — biophysics — Posted on 2018-02-20

578 SETD3 protein is the actin-specific histidine N-methyltransferase

Kwiatkowski, S.; Seliga, A. K.; Veiga-da-Cunha, M.; Vertommen, D.; Terreri, M.; Ishikawa, T.; Grabowska, I.; Jagielski, A. K.; Drozak, J.

10.1101/266882 — biochemistry — Posted on 2018-02-20

579 Enhanced instructed fear learning in delusion-proneness

Petrovic, P.; Louzolo, A.; Almeida, R.; Guitart-Masip, M.; Björnsdotter, M.; Ingvar, M.; Olsson, A.

10.1101/264739 — physiology — Posted on 2018-02-20

580 A positive feedback-based mechanism for constriction rate acceleration during cytokinesis in C. elegans

Khaliullin, R.; Green, R.; Shi, L.; Berns, M.; Gomez-Cavazos, J. S.; Desai, A.; Oegema, K.

10.1101/161133 — cell biology — Posted on 2018-02-20

581 Optimal Therapy Scheduling Based on a Pair of Collaterally Sensitive Drugs

Yoon, N.; Vander Velde, R.; Marusyk, A.; Scott, J.

10.1101/196824 — cancer biology — Posted on 2018-02-20

582 Accelerated brain aging towards transcriptional inversion in a zebrafish model of familial Alzheimer’s disease

Hin, N.; Newman, M.; Kaslin, J.; Douek, A. M.; Lumsden, A.; Zhou, X.-F.; Manucat-Tan, N. B.; Ludington, A.; Adelson, D. L.; Pederson, S.; Lardelli, M.

10.1101/262162 — bioinformatics — Posted on 2018-02-20

583 Local temporal variability reflects functional network integration in the human brain: On the crucial role of the thalamus

Garrett, D.; Epp, S.; Perry, A.; Lindenberger, U.

10.1101/184739 — neuroscience — Posted on 2018-02-20

584 Validation of Davson’s equation in patients suffering from idiopathic Normal Pressure Hydrocephalus

Lalou, A. D.; Levrini, V.; Garnett, M. R.; Nabbanja, E.; Kim, D.-J.; Gergele, L.; Bjornson, A.; Czosnyka, Z. H.; Czosnyka, M.

10.1101/268698 — neuroscience — Posted on 2018-02-20

585 Neural responses to naturalistic clips of behaving animals in two different task contexts

Nastase, S. A.; Halchenko, Y. O.; Connolly, A. C.; Gobbini, M. I.; Haxby, J. V.

10.1101/268144 — neuroscience — Posted on 2018-02-20

586 Human copy number variants are enriched in regions of low mappability

Monlong, J.; Cossette, P.; Meloche, C.; Rouleau, G.; Girard, S. L.; Bourque, G.

10.1101/034165 — genomics — Posted on 2018-02-20

587 Discovering in vivo cytokine eQTL interactions from a lupus clinical trial

Davenport, E. E.; Amariuta, T.; Gutierrez-Arcelus, M.; Slowikowski, K.; Westra, H.-J.; Luo, Y.; Shen, C.; Rao, D. A.; Zhang, Y.; Pearson, S.; von Schack, D.; Beebe, J. S.; Bing, N.; John, S.; Vincent, M. S.; Zhang, B.; Raychaudhuri, S.

10.1101/118703 — genomics — Posted on 2018-02-20

588 Ancestral heterogeneity of ancient Eurasians

Shriner, D.

10.1101/268524 — genetics — Posted on 2018-02-20

589 Ancient genomes from North Africa evidence prehistoric migrations to the Maghreb from both the Levant and Europe

Fregel, R.; Mendez, F. L.; Bokbot, Y.; Martin-Socas, D.; Camalich-Massieu, M. D.; Santana, J.; Morales, J.; Avila-Arcos, M. C.; Underhill, P. A.; Shapiro, B.; Wojcik, G. L.; Rasmussen, M.; Soares, A. E. R.; Kapp, J.; Sockell, A.; Rodriguez-Santos, F. J.; Mikdad, A.; Trujillo-Mederos, A.; Bustamante, C. D.

10.1101/191569 — genetics — Posted on 2018-02-20

590 Tbx1 regulates extracellular matrix- and cell-cell interactions in the second heart field.

Baldini, A.; Alfano, D.; Altomonte, A.; Bilio, M.

10.1101/267906 — developmental biology — Posted on 2018-02-20

591 Conservative method for attenuation of Vertical Electrooculogram based on local suppression of artifact templates from ongoing EEG

Abramov, D. M.; Mourao, C. A.; Galhanone, P. R.; Lazarev, V. V.

10.1101/268763 — bioinformatics — Posted on 2018-02-20

592 Example of Methylome Analysis with MethylIT using Cancer Datasets

Sanchez, R.; Mackenzie, S.

10.1101/261982 — bioinformatics — Posted on 2018-02-20

593 Echo State Networks Ensemble for SSVEP Dynamical Online Detection

Ibanez-Soria, D.; Soria-Frisch, A.; Garcia-Ojalvo, J.; Ruffini, G.

10.1101/268581 — bioengineering — Posted on 2018-02-20

594 Delineating feedback activity in the MAPK and AKT pathways using feedback-enabled Inference of Signaling Activity

Thijssen, B.; Jastrzebski, K.; Beijersbergen, R. L.; Wessels, L. F. A.

10.1101/268359 — systems biology — Posted on 2018-02-20

595 Dynamic PET of Human Liver Inflammation: Impact of Kinetic Modeling with Optimization-Derived Dual-Blood Input Function

Wang, G.; Corwin, M. T.; Olson, K. A.; Badawi, R. D.; Sarkar, S.

10.1101/268748 — physiology — Posted on 2018-02-20

596 Reading memory formation from the eyes

Bergt, A.; Urai, A. E.; Donner, T. H.; Schwabe, L.

10.1101/268490 — neuroscience — Posted on 2018-02-20

597 Borderline personality disorder with cocaine dependence: impulsivity, emotional dysregulation and amygdala functional connectivity

Balducci, T.; Gonzalez-Olvera, J. J.; Angeles-Valdez, D.; Espinoza-Luna, I.; Garza-Villarreal, E. A.

10.1101/268169 — neuroscience — Posted on 2018-02-20

598 Multisensory stimuli improve relative localisation judgments compared to unisensory auditory or visual stimuli

Freeman, L.; Wood, K. C.; Bizley, J.

10.1101/268540 — neuroscience — Posted on 2018-02-20

599 Active Learning of Cortical Connectivity from Two-Photon Imaging Data

Bertran, M.; Martinez, N.; Wang, Y.; Dunson, D.; Sapiro, G.; Ringach, D.

10.1101/268599 — neuroscience — Posted on 2018-02-20

600 Abstract concept learning in a simple neural network inspired by the insect brain

Cope, A. J.; Vasilaki, E.; Minors, D.; Sabo, C.; Marshall, J. A. R.; Barron, A. B.

10.1101/268375 — neuroscience — Posted on 2018-02-20

601 Modality-independent coding of scene categories in prefrontal cortex

Jung, Y.; Larsen, B.; Walther, D. B.

10.1101/142562 — neuroscience — Posted on 2018-02-20

602 Youth-like Precision of Slow Oscillation-Spindle Coupling Promotes Memory Consolidation Across the Adult Lifespan

Muehlroth, B. E.; Sander, M. C.; Fandakova, Y.; Grandy, T. H.; Rasch, B.; Shing, Y. L.; Werkle-Bergner, M.

10.1101/268474 — neuroscience — Posted on 2018-02-20

603 Topology highlights mesoscopic functional equivalence between imagery and perception

Ibanez-Marcelo, E.; Campioni, L.; Phinyomark, A.; Petri, G.; Santarcangelo, E. L.

10.1101/268383 — neuroscience — Posted on 2018-02-20

604 The Effect of Acute Pharmacological Inhibition of Urokinase Plasminogen Activator and Neuropsin Extracellular Proteases on Neuronal Networks in vitro

Van De Vijver, S.; Missault, S.; Van Soom, J.; Van der Veken, P.; Augustyns, K.; Joossens, J.; Dedeurwaerdere, S.; Giugliano, M.

10.1101/263616 — neuroscience — Posted on 2018-02-20

605 A novel antimicrobial alternative of microbiota metabolic product deoxycholic acid controls chicken necrotic enteritis

Wang, H.; Latorre Cardenas, J. D.; Bansal, M.; Al-Rubaye, B.; Tellez, G.; Hargis, B.; Sun, X.

10.1101/215640 — microbiology — Posted on 2018-02-20

606 Microbial Treatment of Soil Contaminated with Spent engine Oil / Biotreatment of Soil Contaminated with Spent Engine by Microorganisms

Ayandele, A. A.

10.1101/268185 — microbiology — Posted on 2018-02-20

607 Mammalian Cell Entry domains are required for bile resistance and virulence in Salmonella

Isom, G.; Rooke, J.; Antunes, C.; Sheehan, E.; Wells, T.; Icke, C.; Cunningham, A.; Cole, J.; Henderson, I.; Rossiter, A.

10.1101/263871 — microbiology — Posted on 2018-02-20

608 Transposable elements generate regulatory novelty in a tissue specific fashion

Trizzino, M.; Kapusta, A.; Brown, C.

10.1101/268771 — genomics — Posted on 2018-02-20

609 Genome-wide analysis of adolescent psychotic-like experiences shows genetic overlap with psychiatric disorders

Pain, O.; Dudbridge, F.; Cardno, A. G.; Freeman, D.; Lu, Y.; Lundstrom, S.; Lichtenstein, P.; Ronald, A.

10.1101/265512 — genetics — Posted on 2018-02-20

610 Understanding 6th-Century Barbarian Social Organization and Migration through Paleogenomics

Amorim, C. E. G.; Vai, S.; Posth, C.; Modi, A.; Koncz, I.; Hakenbeck, S.; La Rocca, M. C.; Mende, B.; Bobo, D.; Pohl, W.; Baricco, L. P.; Bedini, E.; Francalacci, P.; Giostra, C.; Vida, T.; Winger, D.; von Freeden, U.; Ghirotto, S.; Lari, M.; Barbujani, G.; Krause, J.; Caramelli, D.; Geary, P. J.; Veeramah, K. R.

10.1101/268250 — genetics — Posted on 2018-02-20

611 Oligogenic inheritance of congenital heart disease involving a NKX2-5 modifier

Gifford, C. A.; Ranade, S. S.; Samarakoon, R.; Salunga, H. T.; de Soysa, T. Y.; Huang, Y.; Zhou, P.; Elfenbein, A.; Wyman, S. K.; Bui, Y. K.; Cordes Metzler, K. R.; Ursell, P.; Ivey, K. N.; Srivastava, D.

10.1101/266726 — genetics — Posted on 2018-02-20

612 Genetic meta-analysis identifies 10 novel loci and functional pathways for Alzheimer’s disease risk

Jansen, I.; Savage, J.; Watanabe, K.; Bryois, J.; Williams, D.; Steinberg, S.; Sealock, J.; Karlsson, I.; Hagg, S.; Athanasiu, L.; Voyle, N.; Proitsi, P.; Witoelar, A.; Stringer, S.; Aarsland, D.; Almdahl, I.; Andersen, F.; Bergh, S.; Bettella, F.; Bjornsson, S.; Braekhus, A.; Brathen, G.; de Leeuw, C.; Desikan, R.; Djurovic, S.; Dumitrescu, L.; Fladby, T.; Homan, T.; Jonsson, P.; Rongve, A.; Saltvedt, I.; Sando, S.; Selbak, G.; Skene, N.; Snaedal, J.; Stordal, E.; Ulstein, I.; Wang, Y.; White, L.; Hjerling-Leffler, J.; Sullivan, P.; van der Flier, W.; Dobson, R.; Davis, L.; Stefansson, H.; St

10.1101/258533 — genetics — Posted on 2018-02-20

613 Coadapted genomes and selection on hybrids: Fisher’s geometric model explains a variety of empirical patterns

Simon, A.; Bierne, N.; Welch, J. J.

10.1101/237925 — evolutionary biology — Posted on 2018-02-20

614 Developing an automated iterative near-term forecasting system for an ecological study

White, E. P.; Yenni, G. M.; Taylor, S. D.; Christensen, E. M.; Bledsoe, E. K.; Simonis, J. L.; Ernest, S. K. M.

10.1101/268623 — ecology — Posted on 2018-02-20

615 Contact-dependent cell communications drive morphological invariance during ascidian embryogenesis

Guignard, L.; Fiuza, U.-M.; Leggio, B.; Faure, E.; Laussu, J.; Hufnagel, L.; Malandain, G.; Godin, C.; Lemaire, P.

10.1101/238741 — developmental biology — Posted on 2018-02-20

616 APC/C-Vihar regulates centrosome activity and stability in the Drosophila germline

Braun, A. L.; Meghini, F.; Villa-Fombuena, G.; Fernandez, E. M.; Guermont, M.; Glover, D. M.; Martin-Bermudo, M. D.; Gonzalez-Reyes, A.; Kimata, Y.

10.1101/202465 — developmental biology — Posted on 2018-02-20

617 Early lethality of embryos derived from transgenic Xenopus females is associated with reduced ovarian grem1 expression

Beck, C. W.; Ward, J.; Troise, L.; Brochard, C.

10.1101/268235 — developmental biology — Posted on 2018-02-20

618 Diffusion rather than IFT provides most of the tubulin required for axonemal assembly

Harris, J. A.; Van De Weghe, J. M.; Kubo, T.; Witman, G. B.; Lechtreck, K.

10.1101/268573 — cell biology — Posted on 2018-02-20

619 Inferring Cancer Progression from Single Cell Sequencing while allowing loss of mutations

Ciccolella, S.; Soto Gomez, M.; Patterson, M.; Della Vedova, G.; Hajirasouliha, I.; Bonizzoni, P.

10.1101/268243 — bioinformatics — Posted on 2018-02-20

620 Dynamic Network Analysis of the 4D Nucleome

Liu, S.; Chen, P.-Y.; Hero, A.; Rajapakse, I.

10.1101/268318 — bioinformatics — Posted on 2018-02-20

621 Comparative assessment of strategies to identify similar ligand-binding pockets in proteins

Govindaraj, R. G.; Brylinski, M.

10.1101/268565 — bioinformatics — Posted on 2018-02-20

622 Targeted Drug Delivery by Radiation-Induced Tumor Vascular Modulation

Kunjachan, S.; Kotb, S.; Kumar, R.; Pola, R.; Pechar, M.; Gremse, F.; Taleeli, R.; Trichard, F.; Motto-Ros, V.; Sancey, L.; Detappe, A.; Protti, A.; Shanmugam, I.; Ireland, T.; Etrych, T.; Sridhar, S.; Tillement, O.; Makrigiorgos, G. M.; Berbeco, R.

10.1101/268714 — bioengineering — Posted on 2018-02-20

623 Relative Patlak Plot for Dynamic PET Parametric Imaging Without the Need for Early-time Input Function

Zuo, Y.; Qi, J.; Wang, G.

10.1101/268730 — bioengineering — Posted on 2018-02-20

624 Information sharing for a coordination game in fluctuating environments

Paarporn, K.; Eksin, C.; Weitz, J. S.

10.1101/268268 — animal behavior and cognition — Posted on 2018-02-20

625 Making honey bees lie: experimental dissociation of flight experience and dance communication.

Chatterjee, A.; MV, P.; George, E. A.; Basu, P.; Brockmann, A.

10.1101/268292 — animal behavior and cognition — Posted on 2018-02-20

626 Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies

Do, K.; Wahl, S.; Raffler, J.; Molnos, S.; Laimighofer, M.; Adamsky, J.; Suhre, K.; Strauch, K.; Peters, A.; Gieger, C.; Langenberg, C.; Stewart, I.; Theis, F. J.; Grallert, H.; Kastenmueller, G.; Krumsiek, J.

10.1101/260281 — systems biology — Posted on 2018-02-20

627 Microtubule-associated protein IQ67 DOMAIN5 regulates interdigitation of leaf pavement cells in Arabidopsis thaliana

Mitra, D.; Kumari, P.; Quegwer, J.; Klemm, S.; Moeller, B.; Poeschl, Y.; Pflug, P.; Stamm, G.; Abel, S.; Bürstenbinder, K.

10.1101/268466 — plant biology — Posted on 2018-02-20

628 Hypothesis testing in the presence of noisy experimental replications

Vidaurre, D.; Woolrich, M. W.; Karapanagiotidis, T.; Smallwood, J.; Nichols, T. E.

10.1101/268151 — neuroscience — Posted on 2018-02-20

629 Learning to read increases the informativeness of distributed ventral temporal responses

Nordt, M.; Gomez, J.; Natu, V.; Jeska, B.; Barnett, M.; Grill-Spector, K.

10.1101/257055 — neuroscience — Posted on 2018-02-20

630 A topographic axis of transcriptional identity across thalamic projection systems

Phillips, J. W.; Schulmann, A.; Hara, E.; Liu, C.; Wang, L.; Shields, B.; Korff, W.; Lemire, A.; Dudman, J.; Nelson, S. B.; Hantman, A.

10.1101/241315 — neuroscience — Posted on 2018-02-20

631 Yellow Fever, Dengue Fever And West Nile Viruses Co-Circulation In Ogbomoso

Oladipo, E. K.; Oloke, J. K.; Awoyelu, E. H.

10.1101/265819 — microbiology — Posted on 2018-02-20

632 Microbial diversity and toxin risk in tropical freshwater reservoirs of Cape Verde

Semedo-Aguiar, A. P.; Pereira-Leal, J. B.; Leite, R. B.

10.1101/266957 — microbiology — Posted on 2018-02-20

633 Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages

Yang, J.; Mott, D.; Sutiwisesak, R.; Lu, Y. J.; Rosa, F.; Stowell, B.; Babunovic, G.; Lee, J.; Carpenter, S.; Way, S. S.; Fortune, S.; Behar, S. M.

10.1101/262493 — immunology — Posted on 2018-02-20

634 Quantitative Genetic Analysis of the Maize Leaf Microbiome

Wallace, J. G.; Kremling, K. A.; Buckler, E. S.

10.1101/268532 — genetics — Posted on 2018-02-20

635 A High-Resolution Genetic Map for the Laboratory Rat

Littrell, J.; Tsaih, S.-W.; Baud, A.; Rastas, P. M. A.; Solberg-Woods, L.; Flister, M.

10.1101/268227 — genetics — Posted on 2018-02-20

636 Rapid nuclear exclusion of Hcm1 in aging Saccharomyces cerevisiae leads to vacuolar alkalization and replicative senescence

Harkness, T. A. A.; Ghavidel, A.; Prusinkiewicz, M.; Swan, C.; Belak, Z. R.; Eskiw, C. H.; Carvalho, C. E.; Baxi, K.

10.1101/268664 — genetics — Posted on 2018-02-20

637 PlasmoTron: an open-source platform for automated culture of malaria parasites

Sanderson, T.; Rayner, J. C.

10.1101/241596 — genetics — Posted on 2018-02-20

638 Some empirical arguments demonstrating that the latent period varies over the course of a plant disease epidemic

Suffert, F.; Thompson, R. N.

10.1101/148619 — epidemiology — Posted on 2018-02-20

639 From the cage to the wild: Introductions of Psittaciformes to Puerto Rico with emphasis on the invasive ecology of the white-winged parakeet

Falcon, W.; Tremblay, R. L.

10.1101/264937 — ecology — Posted on 2018-02-20

640 Highly efficient CRISPR/Cas9-mediated tissue specific mutagenesis in Drosophila

Poe, A. R.; Wang, B.; Sapar, M. L.; Ji, H.; Li, K.; Onabajo, T.; Fazliyeva, R.; Gibbs, M.; Qiu, Y.; Hu, Y.; Han, C.

10.1101/268482 — developmental biology — Posted on 2018-02-20

641 TRPV4 is the temperature-sensitive ion channel of human sperm

Mundt, N.; Spehr, M.; Lishko, P. V.

10.1101/268409 — cell biology — Posted on 2018-02-20

642 Escherichia coli can survive stress by noisy growth modulation

Patange, O.; Schwall, C.; Jones, M.; Griffith, D.; Phillips, A.; Locke, J.

10.1101/265801 — systems biology — Posted on 2018-02-20

643 Cell death in cells overlying lateral root primordia contributes to organ growth in Arabidopsis

Escamez, S.; Bollhoner, B.; Hall, H.; Andre, D.; Berthet, B.; Voss, U.; Lers, A.; Maizel, A.; Bennett, M.; Tuominen, H.

10.1101/268433 — plant biology — Posted on 2018-02-20

644 Growth- and stress-related defects associated to wall hypoacetylation are strigolactone-dependent

Ramirez, V.; Xiong, G.; Mashiguchi, K.; Yamaguchi, S.; Pauly, M.

10.1101/268417 — plant biology — Posted on 2018-02-20

645 Human cortical pyramidal neurons: From spines to spikes via models

Eyal, G.; Verhoog, M. B.; Testa-Silva, G.; Deitcher, Y.; Benavides-Piccione, R.; DeFelipe, J.; de Kock, C. P. J.; Mansvelder, H. D.; Segev, I.

10.1101/267898 — neuroscience — Posted on 2018-02-20

646 A Probabilistic, Distributed, Recursive Mechanism for Decision-making in the Brain

Caballero, J. A.; Humphries, M. D.; Gurney, K. N.

10.1101/036277 — neuroscience — Posted on 2018-02-20

647 The most informative neural code accounts for population heterogeneity

Zavitz, E.; Price, N. S. C.

10.1101/112037 — neuroscience — Posted on 2018-02-20

648 Handling Multiplicity in Neuroimaging through Bayesian Lenses with Multilevel Modeling

Chen, G.; Xiao, Y.; Taylor, P. A.; Rajendra, J. K.; Riggins, T.; Geng, F.; Redcay, E.; Cox, R. W.

10.1101/238998 — neuroscience — Posted on 2018-02-20

649 Matrin 3-dependent neurotoxicity is modified by nucleic acid binding and nucleocytoplasmic localization

Malik, A.; Miguez, R.; Li, X.; Ho, Y.-S.; Feldman, E.; Barmada, S.

10.1101/268458 — cell biology — Posted on 2018-02-20

650 psichomics: graphical application for alternative splicing quantification and analysis

Saraiva-Agostinho, N.; Barbosa-Morais, N. L.

10.1101/261180 — bioinformatics — Posted on 2018-02-20

651 FDAAA TrialsTracker: A live informatics tool to monitor compliance with FDA requirements to report clinical trial results

DeVito, N. J.; Bacon, S.; Goldacre, B.

10.1101/266452 — clinical trials — Posted on 2018-02-20

652 Common variants in ABCG8 and TRAF3 genes confer risk for gallstone disease and gallbladder cancer in admixed Latinos with Mapuche Native American ancestry

Bustos, B. I.; Perez-Palma, E.; Buch, S.; Azocar, L.; Riveras, E.; Ugarte, G. D.; Toliat, M.; Nuernberg, P.; Lieb, W.; Franke, A.; Hinz, S.; Burmeister, G.; von Shoenfels, W.; Schafmayer, C.; Voelzke, H.; Voelker, U.; Homuth, G.; Lerch, M. M.; Santos, J. L.; Puschel, K.; Bambs, C.; Gutierrez, R. A.; Hampe, J.; De Ferrari, G. V.; Miquel, J. F.

10.1101/265728 — genetics — Posted on 2018-02-20

653 Phospholipid flipping facilitates annexin translocation across membranes

Stewart, S. E.; Ashkenazi, A.; Williamson, A.; Rubinsztein, D. C.; Moreau, K.

10.1101/241976 — cell biology — Posted on 2018-02-20

654 Whole-genome sequencing of parvoviruses from wild and domestic animals in Brazil provides new insights into parvovirus distribution and diversity

Souza, W. M. d.; Dennis, T. P. W.; Fumagalli, M. J.; Araujo, J.; Sabino-Santos, G.; Maia, F. G. M.; Acrani, G. O.; Carrasco, A. O. T.; Romeiro, M. F.; Modha, S.; Vieira, L. C.; Ometto, T. L.; Queiroz, L. H.; Durigon, E. L.; Nunes, M. R. T.; Figueiredo, L. T. M.; Gifford, R. J.

10.1101/268219 — microbiology — Posted on 2018-02-20

655 Tectal stem cells display diverse regenerative capacities

Lindsey, B. W.; Aitkens, G. E.; Tang, J. K.; Khabooshan, M.; Vandestadt, C.; Kaslin, J.

10.1101/268136 — neuroscience — Posted on 2018-02-19

656 From spiral cleavage to bilateral symmetry: The developmental cell lineage of the annelid brain

Vopalensky, P.; Tosches, M. A.; Achim, K.; Handberg-Thorsager, M.; Arendt, D.

10.1101/268177 — developmental biology — Posted on 2018-02-19

657 Crowdsourcing Image Analysis for Plant Phenomics to Generate Ground Truth Data for Machine Learning

Siegel, Z. D.; Zhou, N.; Zarecor, S.; Lee, N.; Campbell, D. A.; Andorf, C. M.; Nettleton, D.; Lawrence-Dill, C. J.; Ganapathysubramanian, B.; Friedberg, I.; Kelly, J. W.

10.1101/265918 — plant biology — Posted on 2018-02-19

658 A majority of HIV persistence during antiretroviral therapy is due to infected cell proliferation

Reeves, D. B.; Duke, E. R.; Wagner, T. A.; Palmer, S. E.; Spivak, A. M.; Schiffer, J. T.

10.1101/146977 — immunology — Posted on 2018-02-19

659 Diet Modifies Colonic Microbiota and CD4+ T Cell Repertoire to Trigger Flares in a Novel Model of Colitis Induced by IL-23

Chen, L.; He, Z.; Iuga, A. C.; Filho, S. M.; Faith, J. J.; Clemente, J. C.; Deshpande, M.; Jayaprakash, A.; Colombel, J.-F.; Lafaille, J. J.; Sachidanandam, R.; Furtado, G. C.; Lira, S. A.

10.1101/262634 — immunology — Posted on 2018-02-19

660 Does a poor childhood associate with higher and steeper inflammation trajectories in the English Longitudinal Study of Ageing?

Tampubolon, G.; Fajarini, M.

10.1101/267559 — epidemiology — Posted on 2018-02-19

661 Phylogenetic factorization of mammalian viruses complements trait-based analyses and guides surveillance efforts

Washburne, A.; Crowley, D. E.; Becker, D. J.; Olival, K. J.; Taylor, M.; Munster, V. J.; Plowright, R. K.

10.1101/267252 — epidemiology — Posted on 2018-02-19

662 Shifting patterns of seasonal influenza epidemics

Coletti, P.; Poletto, C.; Turbelin, C.; Blanchon, T.; Colizza, V.

10.1101/268060 — epidemiology — Posted on 2018-02-19

663 The strong grip of childhood conditions in older Europeans

Tampubolon, G.; Fajarini, M.

10.1101/267526 — epidemiology — Posted on 2018-02-19

664 Cryo-EM structure of the adenosine A2A receptor coupled to an engineered heterotrimeric G protein

Tate, C. G.; Garcia-Nafria, J.; Lee, Y.; Bai, X.; Carpenter, B.

10.1101/267674 — biophysics — Posted on 2018-02-19

665 Generation of functional human adipose tissue in mice from primed progenitor cells

Rojas-Rodriguez, R.; Lujan-Hernandez, J.; Min, S. Y.; DeSouza, T.; Teebagy, P.; Desai, A.; Tessier, H.; Slamin, R.; Siegel-Reamer, L.; Berg, C.; Baez, A.; Lalikos, J.; Corvera, S.

10.1101/267427 — bioengineering — Posted on 2018-02-19

666 Familiarity and Face-Inversion Effect in Japanese Macaques (Macaca fuscata) during the Preferential Looking Task

Tomonaga, M.

10.1101/267716 — animal behavior and cognition — Posted on 2018-02-19

667 Food hardness and stone tool weight in wild primate nut-cracking

Haslam, M.

10.1101/267542 — animal behavior and cognition — Posted on 2018-02-19

668 Gender balance in time-keeping at life science conferences

Edlund, P.; Tranfield, E. M.; van Noort, V.; Siu Ting, K.; Tapani, S.; Hoog, J.

10.1101/267120 — scientific communication and education — Posted on 2018-02-19

669 The co-regulatory interaction of transpiration and water potential, and implications for stomatal conductance models

Beyer, R.; Pretzsch, H.; Cournede, P.-H.

10.1101/237826 — plant biology — Posted on 2018-02-19

670 Silencing of a unique integrated domain nucleotide-binding leucine-rich repeat gene in wheat abolishes Diuraphis noxia resistance

Nicolis, V. F.; Venter, E.

10.1101/261644 — plant biology — Posted on 2018-02-19

671 Acetylcholine disinhibits hippocampal circuits to enable rapid formation of overlapping memory ensembles

Prince, L. Y.; Tsaneva-Atanasova, K.; Clopath, C.; Mellor, J. R.

10.1101/201699 — neuroscience — Posted on 2018-02-19

672 Head-direction cells escaping attractor dynamics in the parahippocampal region

Kornienko, O.; Latuske, P.; Kohler, L.; Allen, K.

10.1101/268110 — neuroscience — Posted on 2018-02-19

673 Divergent effects of healthy ageing on semantic knowledge and control: Evidence from novel comparisons with semantically-impaired patients

Hoffman, P.

10.1101/216192 — neuroscience — Posted on 2018-02-19

674 A neural circuit arbitrates between perseverance and withdrawal in hungry Drosophila

Sayin, S.; De Backer, J.-F.; Wosniack, M. E.; Lewis, L.; Siju, K. P.; Frisch, L.-M.; Schlegel, P.; Edmondson-Stait, A.; Sharifi, N.; Fisher, C. B.; Calle-Schuler, S.; Lauritzen, S.; Bock, D.; Costa, M.; Jefferis, G. S. X. E.; Gjorgjieva, J.; Grunwald Kadow, I.

10.1101/259119 — neuroscience — Posted on 2018-02-19

675 Endospores and other lysis-resistant bacteria comprise a widely shared core community within the human microbiota

Kearney, S. M.; Gibbons, S. M.; Poyet, M.; Gurry, T.; Bullock, K.; Allegretti, J.; Clish, C.; Alm, E. J.

10.1101/221713 — microbiology — Posted on 2018-02-19

676 A reproducible and accurate 14-drug microtitre plate containing bedaquiline and delamanid for susceptibility testing of Mycobacterium tuberculosis

Rancoita, P. M.; Cugnata, F.; Gibertoni Cruz, A. L.; Borroni, E.; Hoosdally, S. J.; Walker, T. M.; Grazian, C.; Davies, T. J.; Peto, T. E.; Crook, D. W.; Fowler, P. W.; Cirillo, D. M.; the CRyPTIC Consortium,

10.1101/244731 — microbiology — Posted on 2018-02-19

677 The plasma biomarker soluble SIGLEC-1 is associated with the type I interferon transcriptional signature, ethnic background and renal disease in systemic lupus erythematosus

Oliveira, J.; Karrar, S.; Rainbow, D.; Pinder, C.; Clarke, P.; Rubio Garcia, A.; Al-Assar, O.; Burling, K.; Vyse, T.; Wicker, L.; Todd, J.; Ferreira, R.

10.1101/266965 — immunology — Posted on 2018-02-19

678 Population Turnover in Remote Oceania Shortly After Initial Settlement

Lipson, M.; Skoglund, P.; Spriggs, M.; Valentin, F.; Bedford, S.; Shing, R.; Buckley, H.; Phillip, I.; Ward, G. K.; Mallick, S.; Rohland, N.; Broomandkhoshbacht, N.; Cheronet, O.; Ferry, M.; Harper, T. K.; Michel, M.; Oppenheimer, J.; Sirak, K.; Stewardson, K.; Auckland, K.; Hill, A. V. S.; Maitland, K.; Oppenheimer, S. J.; Parks, T.; Robson, K.; Williams, T. N.; Kennett, D. J.; Mentzer, A. J.; Pinhasi, R.; Reich, D.

10.1101/268037 — genetics — Posted on 2018-02-19

679 Heterochromatin delays CRISPR-Cas9 mutagenesis but does not influence repair outcome

Kallimasioti-Pazi, E. M.; Thelakkad Chathoth, K.; Taylor, G. C.; Meynert, A.; Ballinger, T.; Kelder, M. J.; Lalevee, S.; Sanli, I.; Feil, R.; Wood, A. J.

10.1101/267690 — genetics — Posted on 2018-02-19

680 The population genetics of spatial sorting

Phillips, B.; Perkins, T. A.

10.1101/210088 — evolutionary biology — Posted on 2018-02-19

681 Detection of Plasmodium berghei infected Anopheles stephensi using near-infrared spectroscopy

Esperanca, P. M.; Blagborough, A. M.; Da, D. F.; Dowell, F. E.; Churcher, T. S.

10.1101/195925 — epidemiology — Posted on 2018-02-19

682 Response to Therapeutic Sleep Deprivation: A Naturalistic Study of Clinical and Genetic Factors and Post-Treatment Depressive Symptom Trajectory

Trautmann, N.; Foo, J. C.; Frank, J.; Witt, S. H.; Streit, F.; Treutlein, J.; Conrad von Heydendorff, S.; Gilles, M.; Major Depressive Disorder Working Group of the PGC, ; Forstner, A. J.; Ebner-Priemer, U.; Noethen, M. M.; Deuschle, M.; Rietschel, M.

10.1101/179457 — epidemiology — Posted on 2018-02-19

683 Detection of Plasmodium berghei infected Anopheles stephensi using near-infrared spectroscopy

Esperanca, P. M.; Blagborough, A. M.; Da, D. F.; Dowell, F. E.; Churcher, T. S.

10.1101/195925 — epidemiology — Posted on 2018-02-19

684 Application of the Mesolens for sub-cellular resolution imaging of intact larval and whole adult Drosophila

McConnell, G.; Amos, W. B.

10.1101/267823 — developmental biology — Posted on 2018-02-19

685 Ripple-Mapping for the Detection of Long Duration Action Potential Areas in Patients with Brugada Syndrome

Providencia, R.; Cavaco, D.; Carmo, P.; Pisani, C.; Costa, F. M.; Faustino, M.; Morgado, F.; Lambiase, P. D.; Scanavacca, M.; Adragao, P.

10.1101/263145 — clinical trials — Posted on 2018-02-19

686 Efflux Pumps Represent Possible Evolutionary Convergence onto the Beta Barrel Fold

Franklin, M. W.; Nepomnyachiy, S.; Feehan, R.; Ben-Tal, N.; Kolodny, R.; Slusky, J. S. G.

10.1101/268029 — biophysics — Posted on 2018-02-19

687 Bayesian phylodynamic inference with complex models

Volz, E.; Siveroni, I.

10.1101/268052 — bioinformatics — Posted on 2018-02-19

688 Structure and mutagenic analysis of the lipid II flippase MurJ from Escherichia coli

Zheng, S.; Sham, L.-T.; Rubino, F. A.; Brock, K.; Robins, W. P.; Mekalanos, J. J.; Marks, D. S.; Bernhardt, T. G.; Kruse, A. C.

10.1101/260596 — biochemistry — Posted on 2018-02-19

689 Universal transcriptomic signature of age reveals temporal scaling of Caenorhabditis elegans aging trajectories

Tarkhov, A. E.; Alla, R.; Ayyadevara, S.; Pyatnitskiy, M.; Menshikov, L. I.; Shmookler Reis, R. J.; Fedichev, P. O.

10.1101/207647 — systems biology — Posted on 2018-02-19

690 Incomplete reprogramming of cell-specific epigenetic marks during asexual reproduction leads to heritable phenotypic variation in plants

Wibowo, A.; Becker, C.; Durr, J.; Price, J.; Staepen, S.; Hilton, S.; Putra, H.; Papareddy, R.; Saintain, Q.; Harvey, S.; Bending, G. D.; Schulze-Lefert, P.; Weigel, D.; Gutierrez-Marcos, J.

10.1101/267955 — plant biology — Posted on 2018-02-19

691 ALOXE3 is a hepatic fasting-responsive lipoxygenase that enhances insulin sensitivity via hepatic PPARγ

Higgins, C. B.; Zhang, Y.; Mayer, A. L.; Fujiwara, H.; Stothard, A. I.; Graham, M.; Swarts, B. M.; DeBosch, B. J.

10.1101/267781 — physiology — Posted on 2018-02-19

692 Exosomes and exosomal miRNAs from muscle-derived fibroblasts promote skeletal muscle fibrosis

Mora, M.; Zanotti, S.; Gibertini, S.; Blasevich, F.; Bragato, C.; Saredi, S.; Introna, C.; Bernasconi, P.; Maggi, L.; Mantegazza, R.

10.1101/267963 — pathology — Posted on 2018-02-19

693 Hypothesis testing in the presence of noisy experimental replications

Vidaurre, D.; Woolrich, M. W.; Karapanagiotidis, T.; Smallwood, J.; Nichols, T. E.

10.1101/268151 — neuroscience — Posted on 2018-02-19

694 Dissociable effects of prediction and integration during language comprehension: Evidence from a large-scale study using brain potentials

Nieuwland, M. S.; Barr, D. J.; Bartolozzi, F.; Busch-Moreno, S.; Darley, E.; Donaldson, D. I.; Ferguson, H. J.; Fu, X.; Heyselaar, E.; Huettig, F.; Husband, E. M.; Ito, A.; Kazanina, N.; Kogan, V.; Kohut, Z.; Kulakova, E.; Meziere, D.; Politzer-Ahles, S.; Rousselet, G.; Rueschemeyer, S.-A.; Segaert, K.; Tuomainen, J.; Von Grebmer Zu Wolfsthurn, S.

10.1101/267815 — neuroscience — Posted on 2018-02-19

695 Human noise blindness drives suboptimal cognitive inference

Herce Castanon, S.; Bang, D.; Moran, R.; Ding, J.; Egner, T.; Summerfield, C.

10.1101/268045 — neuroscience — Posted on 2018-02-19

696 Human cortical pyramidal neurons: From spines to spikes via models

Eyal, G.; Verhoog, M. B.; Testa-Silva, G.; Deitcher, Y.; Benavides-Piccione, R.; DeFelipe, J.; de Kock, C. P. J.; Mansvelder, H. D.; Segev, I.

10.1101/267898 — neuroscience — Posted on 2018-02-19

697 Probing the limits of alpha power lateralization as a neural marker of selective attention in middle-aged and older listeners

Tune, S.; Woestmann, M.; Obleser, J.

10.1101/267989 — neuroscience — Posted on 2018-02-19

698 Spatial contextual cueing is not a limiting factor for expert performance in the domain of team sports or action video game playing

Schmidt, A.; Pollmann, S.; Geringswald, F.

10.1101/267872 — neuroscience — Posted on 2018-02-19

699 Tau seeding activity anticipates phospho-tau pathology in Alzheimer’s disease

Kaufman, S. K.; Del Tredici, K.; Thomas, T. L.; Braak, H.; Diamond, M. I.

10.1101/267724 — neuroscience — Posted on 2018-02-19

700 Lifestyle activities in mid-life contribute to cognitive reserve in late-life, independent of education, occupation and late-life activities

Chan, D.; Shafto, M.; Kievit, R.; Matthews, F.; Spink, M.; Valenzuela, M.; Cam-CAN, ; Henson, R.

10.1101/267831 — neuroscience — Posted on 2018-02-19

701 Distinct contributions of functional and deep neural network features to representational similarity of scenes in human brain and behavior

Groen, I.; Greene, M. R.; Baldassano, C.; Fei-Fei, L.; Beck, D. M.; Baker, C. I.

10.1101/207530 — neuroscience — Posted on 2018-02-19

702 Tdrd6a regulates the aggregation of Buc into functional subcellular compartments that drive germ cell specification

Roovers, E. F.; Kaaij, L. J.; Redl, S.; Bronkhorst, A. W.; Wiebrands, K.; de Jesus Domingues, A. M.; Huang, H.-Y.; Han, C.-T.; Salvenmoser, W.; Gruen, D.; Butter, F.; van Oudenaarden, A.; Ketting, R. F.

10.1101/267971 — molecular biology — Posted on 2018-02-19

703 Evolution of subgenomic RNA shapes dengue virus adaptation and epidemiological fitness

Finol, E.; Ooi, E. E.

10.1101/267922 — microbiology — Posted on 2018-02-19

704 Familial hypercholesterolemia: a single-nucleotide variant (SNV) in mosaic at the Low density lipoprotein receptor (LDLR)

Rodriguez Novoa, S.; Alonso, C.; Rodriguez Jimenez, C.; Rodriguez-Laguna, L.; Gordo, G.; Martinez-Glez, V.; Garcia Polo, I.

10.1101/266874 — genetics — Posted on 2018-02-19

705 STAG: Species Tree Inference from All Genes

Emms, D.; Kelly, S.

10.1101/267914 — evolutionary biology — Posted on 2018-02-19

706 Habitat choice stabilizes metapopulation dynamics through increased ecological specialisation.

Mortier, F.; Jacob, S.; Vandegehuchte, M. L.; Bonte, D.

10.1101/267575 — evolutionary biology — Posted on 2018-02-19

707 Changes in the neuropeptide complement correlate with nervous system architectures in xenacoelomorphs

Thiel, D.; Franz-Wachtel, M.; Aguilera, F.; Hejnol, A.

10.1101/265579 — evolutionary biology — Posted on 2018-02-19

708 Understanding policing as a mechanism of cheater control in cooperating bacteria

Wechsler, T.; Kuemmerli, R.; Dobay, A.

10.1101/267799 — evolutionary biology — Posted on 2018-02-19

709 Analyzing contentious relationships and outlier genes in phylogenomics

Walker, J. F.; Brown, J. W.; Smith, S. A.

10.1101/115774 — evolutionary biology — Posted on 2018-02-19

710 A Universal Temperature-Dependence of Mutational Fitness Effects

Berger, D.; Stangberg, J.; Walters, R. J.

10.1101/268011 — evolutionary biology — Posted on 2018-02-19

711 Microbes follow Humboldt: temperature drives plant and soil microbial diversity patterns from the Amazon to the Andes

Nottingham, A.; Fierer, N.; Turner, B.; Whitaker, J.; Ostle, N.; McNamara, N.; Bardgett, R.; Leff, J.; Salinas, N.; Silman, M.; Kruuk, L.; Meir, P.

10.1101/079996 — ecology — Posted on 2018-02-19

712 Heterocyclic sterol probes for live monitoring of sterol trafficking and lysosomal storage disorders

Kralova, J.; Jurasek, M.; Krcova, L.; Dolensky, B.; Novotny, I.; Dusek, M.; Rottnerova, Z.; Kahle, M.; Drasar, P.; Bartunek, P.; Kral, V.

10.1101/267948 — cell biology — Posted on 2018-02-19

713 Octadecaneuropeptide prevents toxicity induced by 6-hydroxydopamine in cultured rat astrocyte: involvement of the endogenous antioxidant systems and the intrinsic apoptotic pathway

Kaddour, H.; Hamdi, Y.; Vaudry, D.; Leprince, J.; Vaudry, H.; Tonon, M.-C.; Amri, M.; Masmoudi-Kouki, O.

10.1101/266379 — cell biology — Posted on 2018-02-19

714 Direct measurement of myofilament calcium in living cardiomyocytes

Robinson, P.; Sparrow, A. J.; Broyles, C. N.; Sievert, K.; Chang, Y.-F.; Brook, F. A.; Zhang, X.; Watkins, H.; Abassi, Y. A.; Geeves, M. A.; Redwood, C.; Daniels, M. J.

10.1101/268003 — cell biology — Posted on 2018-02-19

715 Phosphorylation of the exocyst subunit Exo70B2 contributes to the regulation of its function

Teh, O.-k.; Lee, C.-W.; Ditengou, F. A.; Klecker, T.; Furlan, G.; Zietz, M.; Hause, G.; Eschen-Lippold, L.; Hoehenwarter, W.; Lee, J.; Ott, T.; Trujillo, M.

10.1101/266171 — cell biology — Posted on 2018-02-19

716 Application of Polymersomes Engineered to Target P32 Protein for Detection of Small Breast Tumors in Mice

Simon-Gracia, L.; Scodeller, P.; Salzar Fuentes, S.; Gomez Vallejo, V.; Rios, X.; San Sebastian, E.; Sidorenko, V.; Di Silvio, D.; Suck, M.; De Lorenzi, F.; Yokota Rizzo, L.; von Stillfried, S.; Kilk, K.; Lammers, T.; Moya, S. E.; Teesalu, T.

10.1101/187716 — cancer biology — Posted on 2018-02-19

717 A genome-wide miRNA screen identifies regulators of tetraploid cell proliferation

Vittoria, M. A.; Shenk, E. M.; O'Rourke, K. P.; Bolgioni, A. F.; Lim, S.; Kacprzak, V.; Quinton, R. J.; Ganem, N. J.

10.1101/266395 — cancer biology — Posted on 2018-02-19

718 Live single molecule microscopy of HIV-1 assembly in host T cells reveals a spatio-temporal effect of the viral genome.

Floderer, C.; Masson, J.-B.; Boiley, E.; Georgeault, S.; Merida, P.; El Beheiry, M.; Dahan, M.; Roigeard, P.; Sibarita, J.-B.; Favard, C.; Muriaux, D.

10.1101/267930 — biophysics — Posted on 2018-02-19

719 High precision wavefront control in Point Spread Function engineering for single emitter localization

Siemons, M.; Hulleman, C.; Thorsen, R.; Smith, C.; Stallinga, S.

10.1101/267864 — biophysics — Posted on 2018-02-19

720 Pleiotropic and Epistatic Network-Based Discovery: Integrated Networks for Target Gene Discovery

Weighill, D. A.; Jones, P.; Shah, M.; Ranjan, P.; Muchero, W.; Schmutz, J.; Sreedasyam, A.; Macaya-Sanz, D.; Sykes, R.; Zhao, N.; Martin, M. Z.; DiFazio, S.; Tschaplinski, T. J.; Tuskan, G.; Jacobson, D.

10.1101/267997 — bioinformatics — Posted on 2018-02-19

721 C3: An R package for cross-species compendium-based cell-type identification

Kabir, M. H.; Djordjevic, D.; O'Connor, M. D.; Ho, J.

10.1101/267880 — bioinformatics — Posted on 2018-02-19

722 Matching drug transcriptional signatures to rare losses disrupting synaptic gene networks identifies known and novel candidate drugs for schizophrenia

Merico, D.; Wang, X.; Yuen, R. K. C.; Scherer, S. W.; Bassett, A. S.

10.1101/268094 — bioinformatics — Posted on 2018-02-19

723 Characterizing higher order structures of chromatin in human cells

Schwartz, U.; Nemeth, A.; Diermeier, S.; Exler, J.; Hansch, S.; Maldonado, R.; Heizinger, L.; Merkl, R.; Laengst, G.

10.1101/267856 — genomics — Posted on 2018-02-19

724 Revisiting the evolutionary analysis of mammalian CRISPs reveals positive selection

Vicens, A.; Trevino, C.

10.1101/266940 — evolutionary biology — Posted on 2018-02-19

725 QsRNA-seq: a method for high-throughput profiling and quantifying small RNAs

Fishman, A.; Light, D.; Lamm, A. T.

10.1101/265603 — genomics — Posted on 2018-02-19

726 Cell atlas of human uterus

Wu, B.; Li, Y.; Liu, Y.; Jin, K.; Zhao, K.; An, C.; Li, Q.; Gong, L.; Zhao, W.; Hu, J.; Qian, J.; Ouyang, H.; Zou, X.

10.1101/267849 — cell biology — Posted on 2018-02-19

727 Binding of general anesthetics to ion channels

Stock, L.; Hosoume, J.; Cirqueira, L.; Treptow, W.

10.1101/266809 — biophysics — Posted on 2018-02-19

728 Removing neural correlations improves population sensitivity in MT/MST in response to random dot stimuli

Chaplin, T. A.; Hagan, M. A.; Allitt, B. J.; Rosa, M. G.; Leo, L.

10.1101/267732 — neuroscience — Posted on 2018-02-19

729 Data-driven clustering reveals a link between symptoms and functional brain connectivity in depression

Maglanoc, L. A. M.; Landro, N. I.; Jonassen, R.; Kaufmann, T.; Cordova-Palomera, A.; Hilland, E.; Westlye, L. T.

10.1101/267591 — neuroscience — Posted on 2018-02-19

730 Spatial moment description of birth-death-movementprocesses incorporating the effects of crowding andobstacles

Surendran, A.; Plank, M.; Simpson, M. J.

10.1101/267708 — biophysics — Posted on 2018-02-18

731 Stochasticity of cellular growth: sources, propagation and consequences

Thomas, P.; Terradot, G.; Danos, V.; Weisse, A.

10.1101/267658 — systems biology — Posted on 2018-02-18

732 Mechanistic model of temperature influence on flowering through whole-plant accumulation of FT

Kinmonth-Schultz, H. A.; MacEwen, M. J.; Seaton, D. D.; Millar, A. J.; Imaizumi, T.; Kim, S.-H.

10.1101/267104 — plant biology — Posted on 2018-02-18

733 An inhibitor of apoptosis (SfIAP) interacts with SQUAMOSA promoter binding protein (SBP) transcription factors that exhibit pro-death characteristics

Kessens, R.; Sorensen, N.; Kabbage, M.

10.1101/267435 — plant biology — Posted on 2018-02-18

734 The dyslexia susceptibility KIAA0319 gene shows a highly specific expression pattern during zebrafish development supporting a role beyond neuronal migration.

Gostic, M.; Martinelli, A.; Tucker, C.; Yang, Z.; Gasparoli, F.; Dholakia, K.; Sillar, K.; Tello, J.; Paracchini, S.

10.1101/267617 — neuroscience — Posted on 2018-02-18

735 The low dimensional dynamic and integrative core of cognition in the human brain

Shine, J. M.; Breakspear, M.; Bell, P.; Ehgoetz Martens, K.; Shine, R.; Koyejo, O.; Sporns, O.; Poldrack, R.

10.1101/266635 — neuroscience — Posted on 2018-02-18

736 The pharmacological perturbation of brain zinc impairs BDNF-related signalling and the cognitive performances of young mice

Frazzini, V.; Granzotto, A.; Bomba, M.; Massetti, N.; Castelli, V.; d'Aurora, M.; Punzi, M.; Iorio, M.; Mosca, A.; Delli Pizzi, S.; Gatta, V.; Cimini, A.; Sensi, S. L.

10.1101/267609 — neuroscience — Posted on 2018-02-18

737 Temporal and spatial factors that influence magnetotaxis in C. elegans

Vidal-Gadea, A.; Caldart, C.; Bainbridge, C.; Clites, B.; Palacious, B.; Bakhtiari, L.; Gordon, V.; Golombek, D.; Pierce, J.

10.1101/252700 — neuroscience — Posted on 2018-02-18

738 Data management and sharing in neuroimaging: Practices and perceptions of MRI researchers

Borghi, J. A.; Van Gulick, A. E.

10.1101/266627 — neuroscience — Posted on 2018-02-18

739 Alpha-band oscillations track the retrieval of precise spatial representations from long-term memory

Sutterer, D. W.; Foster, J. J.; Serences, J. T.; Vogel, E. K.; Awh, E.

10.1101/207860 — neuroscience — Posted on 2018-02-18

740 Dynamic embedding of salience coding in hippocampal spatial maps

Sato, M.; Mizuta, K.; Islam, T.; Kawano, M.; Takekawa, T.; Gomez-Dominguez, D.; Kim, K.; Yamakawa, H.; Ohkura, M.; Fukai, T.; Nakai, J.; Hayashi, Y.

10.1101/266767 — neuroscience — Posted on 2018-02-18

741 Prediction-related neural activity during silent periods is sharply tuned

Demarchi, G.; Sanchez, G.; Weisz, N.

10.1101/266841 — neuroscience — Posted on 2018-02-18

742 Non-histone human chromatin protein, PC4 is critical for genomic integrity and negatively regulates autophagy

Sikder, S.; Kumari, S.; Mustafi, P.; Ramdas, N.; Padhi, S.; Saha, A.; Banerjee, B.; Manjithaya, R.; Kundu, T. K.

10.1101/266932 — molecular biology — Posted on 2018-02-18

743 Serum-mediated cleavage of Bacillus anthracis Protective Antigen is a two-step process that involves a serum carboxypeptidase

Goldman, D. L.; Nieves, E.; Nakouzi, A.; Rivera, J.; Phyu, E. E.; Win, T. H.; Achkar, J.; Casadevall, A.

10.1101/267369 — microbiology — Posted on 2018-02-18

744 Microbial diversity and toxin risk in tropical freshwater reservoirs of Cape Verde

Semedo-Aguiar, A. P.; Pereira-Leal, J. B.; Leite, R. B.

10.1101/266957 — microbiology — Posted on 2018-02-18

745 Microbial Engraftment and Efficacy of Fecal Microbiota Transplant for Clostridium difficile Patients With and Without IBD

Hirten, R. P.; Grinspan, A.; Fu, S.-C.; Luo, Y.; Suarez-Farinas, M.; Rowland, J.; Contijoch, E. J.; Mogno, I.; Yang, N.; Luong, T.; Labrias, P. R.; Peter, I.; Cho, J. H.; Sands, B. E.; Colombel, J.-F.; Faith, J. J.; Clemente, J. C. C.

10.1101/267492 — microbiology — Posted on 2018-02-18

746 De novo assembly of two Swedish genomes reveals missing segments from the human GRCh38 reference and improves variant calling of population-scale sequencing data

Ameur, A.; Che, H.; Martin, M.; Bunikis, I.; Dahlberg, J.; Höijer, I.; Häggqvist, S.; Vezzi, F.; Nordlund, J.; Olason, P.; Feuk, L.; Gyllensten, U.

10.1101/267062 — genomics — Posted on 2018-02-18

747 Differential Expression of Coding and Long Noncoding RNAs in Keratoconus-affected Corneas

Khaled, M. L.; Bykhovskaya, Y.; Yablonski, S. E.; Li, H.; Drewry, M. D.; Aboobakar, I. F.; Estes, A.; Gao, X.; Stamer, W. D.; Xu, H.; Allingham, R. R.; Hauser, M. A.; Rabinowitz, Y. S.; Liu, Y.

10.1101/267054 — genomics — Posted on 2018-02-18

748 Rapid low-cost assembly of the Drosophila melanogaster reference genome using low-coverage, long-read sequencing

Solares, E. A.; Chakraborty, M.; Miller, D. E.; Kalsow, S.; Hall, K. E.; Perera, A. G.; Emerson, J. J.; Hawley, R. S.

10.1101/267401 — genomics — Posted on 2018-02-18

749 Divergent genetic mechanisms lead to spiny hair in mammals

Goncalves, G. L.; Maestri, R.; Moreira, G. R. P.; Jacobi, M. A. M.; Freitas, T. R. O.; Hoekstra, H. E.

10.1101/267385 — genetics — Posted on 2018-02-18

750 Population Replacement in Early Neolithic Britain

Brace, S.; Diekmann, Y.; Booth, T. J.; Faltyskova, Z.; Rohland, N.; Mallick, S.; Ferry, M.; Michel, M.; Oppenheimer, J.; Broomandkhoshbacht, N.; Stewardson, K.; Walsh, S.; Kayser, M.; Schulting, R.; Craig, O. E.; Sheridan, A.; Pearson, M. P.; Stringer, C.; Reich, D.; Thomas, M. G.; Barnes, I.

10.1101/267443 — evolutionary biology — Posted on 2018-02-18

751 Evolutionary insights into Bean common mosaic necrosis virus and Cowpea aphid borne mosaic virus using global isolates and thirteen new near complete genomes from Kenya

Wainaina, J. M.; Kubatko, L.; Harvey, J.; Ateka, E.; Makori, T.; Karanja, D.; Boykin, L. M.; Kehoe, M. A.

10.1101/266858 — evolutionary biology — Posted on 2018-02-18

752 Gene expression is stronger associated with behaviour than with age and fertility in ant workers

Kohlmeier, P.; Alleman, A. R.; Libbrecht, R.; Foitzik, S.; Feldmeyer, B.

10.1101/267336 — evolutionary biology — Posted on 2018-02-18

753 A Likelihood-Free Inference Framework for Population Genetic Data using Exchangeable Neural Networks

Chan, J.; Perrone, V.; Spence, J. P.; Jenkins, P. A.; Mathieson, S.; Song, Y. S.

10.1101/267211 — evolutionary biology — Posted on 2018-02-18

754 Soil detrital inputs increase stimulate bacterial saprotrophs with different timing and intensity compared to fungal saprotrophs

Sukdeo, N.; Teen, E.; Rutherford, P. M.; Massicotte, H. B.; Egger, K. N.

10.1101/266684 — ecology — Posted on 2018-02-18

755 Effects of chronic thermal stress on the reproductive performance of male Octopus maya

Lopez-Galindo, L. L.; Galindo-Sanchez, C. E.; Olivares, A.; Avila-Poveda, O. H.; Diaz, F.; Juarez, O.; Lafarga, F.; Caamal-Monsreal, C.; Pantoja-Perez, J.; Rosas, C.

10.1101/267476 — ecology — Posted on 2018-02-18

756 Role of the novel endoribonuclease SLFN14 and its disease causing mutations in ribosomal degradation

Fletcher, S. J.; Pisareva, V. P.; Khan, A.; Tcherepanov, A.; Morgan, N. V.; Pisarev, A. V.

10.1101/267633 — cell biology — Posted on 2018-02-18

757 Integrated single-nucleotide and structural variation signatures of DNA-repair deficient human cancers

Funnell, T.; Zhang, A.; Shiah, Y.-J.; Grewal, D.; Lesurf, R.; McKinney, S.; Bashashati, A.; Wang, Y. K.; Boutros, P.; Shah, S.

10.1101/267500 — cancer biology — Posted on 2018-02-18

758 Collective motion conceals fitness differences in crowded cellular populations

Kayser, J.; Schreck, C.; Gralka, M.; Fusco, D.; Hallatschek, O.

10.1101/267286 — biophysics — Posted on 2018-02-18

759 MiLeSIM: combining super-resolution and machine learning permits high-throughput virus structure analysis

Laine, R. F.; Goodfellow, G.; Young, L. J.; Travers, J.; Carroll, D.; Dibben, O.; Bright, H.; Kaminski, C. F.

10.1101/266551 — biophysics — Posted on 2018-02-18

760 Statistical Inference in Cell Lineage Trees

Hicks, D. G.; Speed, T. P.; Yassin, M.; Russell, S. M.

10.1101/267450 — bioinformatics — Posted on 2018-02-18

761 LimeSeg: A coarsed-grained lipid membrane simulation for 3D image segmentation

Machado, S.; Mercier, V.; Chiaruttini, N.

10.1101/267534 — bioinformatics — Posted on 2018-02-18

762 Investigation of Electrical Stimulation Effect on Intracellular Calcium Dynamics Using Locally Uniform Mesh Refinement

Oftadeh, M. O.

10.1101/267294 — systems biology — Posted on 2018-02-18

763 Medical consequences of pathogenic CNVs in adults: Analysis of the UK Biobank

Crawford, K.; Bracher-Smith, M.; Kendall, K. M.; Rees, E.; Pardinas, A. F.; Einon, M.; Escott-Price, V.; Walters, J. T.; O'Donovan, M. C.; Owen, M. J.; Kirov, G.

10.1101/264077 — genomics — Posted on 2018-02-18

764 Parental legacy, demography, and introgression influenced the evolution of the two subgenomes of the tetraploid Capsella bursa-pastoris (Brassicaceae)

Kryvokhyzha, D.; Salcedo, A.; Eriksson, M. C.; Duan, T.; Tawari, N.; Chen, J.; Guerrina, M.; Kreiner, J. M.; Kent, T. V.; Lagercrantz, U.; Stinchcombe, J. R.; Glemin, S.; Wright, S. I.; Lascoux, M.

10.1101/234096 — evolutionary biology — Posted on 2018-02-18

765 Constriction rate modulation can drive cell size control and homeostasis in C. crescentus

Lambert, A.; Vanhecke, A.; Archetti, A.; Holden, S.; Schaber, F.; Pincus, Z.; Laub, M. T.; Goley, E. D.; Manley, S.

10.1101/266817 — biophysics — Posted on 2018-02-18

766 A Fast Adaptive Algorithm for Computing Whole-Genome Homology Maps

Jain, C.; Koren, S.; Dilthey, A.; Phillippy, A. M.; Aluru, S.

10.1101/259986 — bioinformatics — Posted on 2018-02-18

767 Crowdsourcing Image Analysis for Plant Phenomics to Generate Ground Truth Data for Machine Learning

Siegel, Z. D.; Zhou, N.; Zarecor, S.; Lee, N.; Campbell, D. A.; Andorf, C. M.; Nettleton, D.; Lawrence-Dill, C. J.; Ganapathysubramanian, B.; Friedberg, I.; Kelly, J. W.

10.1101/265918 — plant biology — Posted on 2018-02-18

768 A molecular rack and pinion actuates a cell-surface adhesin and enables bacterial gliding motility

Shrivastava, A.; Berg, H. C.

10.1101/267583 — microbiology — Posted on 2018-02-18

769 Some empirical arguments demonstrating that the latent period varies over the course of a plant disease epidemic

Suffert, F.; Thompson, R. N.

10.1101/148619 — epidemiology — Posted on 2018-02-18

770 A Fast Adaptive Algorithm for Computing Whole-Genome Homology Maps

Jain, C.; Koren, S.; Dilthey, A.; Phillippy, A. M.; Aluru, S.

10.1101/259986 — bioinformatics — Posted on 2018-02-18

771 Paradox resolved: stop signal race model with negative dependence

Colonius, H.; Diederich, A.

10.1101/158485 — animal behavior and cognition — Posted on 2018-02-18

772 FPtool a software tool to obtain in silico genotype-phenotype signatures and fingerprints based on massive model simulations

Santos, G.; Vera, J.

10.1101/266775 — systems biology — Posted on 2018-02-18

773 Metagenomic analysis with strain-level resolution reveals fine-scale variation in the human pregnancy microbiome

Goltsman, D. S. A.; Sun, C. L.; Proctor, D. M.; DiGiulio, D. B.; Robaczewska, A.; Thomas, B. C.; Shaw, G. M.; Stevenson, D. K.; Holmes, S. P.; Banfield, J. F.; Relman, D. A.

10.1101/266700 — microbiology — Posted on 2018-02-18

774 Non-antibiotic antimicrobial triclosan induces multiple antibiotic resistance through genetic mutation

Lu, J.; Jin, M.; Nguyen, S.; Mao, L.; Li, J.; Coin, L. J. M.; Yuan, Z.; Guo, J.

10.1101/267302 — microbiology — Posted on 2018-02-18

775 Family-Companion: analyse, visualise, browse, query and share your homology clusters

Cottret, L.; Rancurel, C.; Briand, M.; Carrere, S.

10.1101/266742 — bioinformatics — Posted on 2018-02-18

776 Estimating the cortex-wide overlap between wordless narrative scene comprehension, reading comprehension, and topological visual, auditory, and somatomotor maps

Sood, M. R.; Sereno, M. I.

10.1101/264002 — neuroscience — Posted on 2018-02-18

777 Aging alters envelope representations of speech-like sounds in the inferior colliculus

Parthasarathy, A.; Herrmann, B.; Bartlett, E. L.

10.1101/266650 — neuroscience — Posted on 2018-02-18

778 High-quality genome assemblies of 15 Drosophila species generated using Nanopore sequencing

Miller, D. E.; Staber, C.; Zeitlinger, J.; Hawley, R. S.

10.1101/267393 — genomics — Posted on 2018-02-18

779 diploS/HIC: an updated approach to classifying selective sweeps

Kern, A. D.; Schrider, D. R.

10.1101/267229 — evolutionary biology — Posted on 2018-02-18

780 FALCON: a method to infer metagenomic composition of ancient DNA

Pratas, D.; Pinho, A. J.; Silva, R. M.; Rodrigues, J.; Hosseini, M.; Caetano, T.; Ferreira, P.

10.1101/267179 — bioinformatics — Posted on 2018-02-18

781 DNAscan: a fast, computationally and memory efficient bioinformatics pipeline for the analysis of DNA next-generation-sequencing data

Iacoangeli, A.; Al Khleifat, A.; Sproviero, W.; Shatunov, A.; Jones, A.; Dobson, R.; Newhouse, S. J.; Al-Chalabi, A.

10.1101/267195 — bioinformatics — Posted on 2018-02-18

782 Generation of functional human adipose tissue in mice from primed progenitor cells

Rojas-Rodriguez, R.; Lujan-Hernandez, J.; Min, S. Y.; DeSouza, T.; Teebagy, P.; Desai, A.; Tessier, H.; Slamin, R.; Siegel-Reamer, L.; Berg, C.; Baez, A.; Lalikos, J.; Corvera, S.

10.1101/267427 — bioengineering — Posted on 2018-02-18

783 Inverted Face with Upright Body:Evidence for Face Inversion Effect in Japanese Macaques (Macaca fuscata) under the Preferential Looking Procedure

Tomonaga, M.

10.1101/266676 — animal behavior and cognition — Posted on 2018-02-18

784 Microbiota Accessible Carbohydrates Suppress Clostridium difficile in a Murine Model

Hryckowian, A. J.; Van Treuren, W.; Smits, S. A.; Davis, N. M.; Gardner, J. O.; Bouley, D. M.; Sonnenburg, J. L.

10.1101/243253 — microbiology — Posted on 2018-02-17

785 A cloning-free method for CRISPR/Cas9-mediated genome editing in fission yeast

Zhang, X.-R.; He, J.-B.; Wang, Y.-Z.; Du, L.-L.

10.1101/239673 — genetics — Posted on 2018-02-17

786 Standard operating procedure for somatic variant refinement of tumor sequencing data

Barnell, E. K.; Ronning, P.; Campbell, K. M.; Krysiak, K.; Ainscough, B. J.; Ramirez, C.; Skidmore, Z. L.; Gomez, F.; Trani, L.; Matlock, M.; Wagner, A. H.; Swamidass, S. J.; Griffith, M.; Griffith, O. L.

10.1101/266262 — genetics — Posted on 2018-02-17

787 The clinician impact and financial cost to the NHS of litigation over pregabalin: a cohort study in English primary care

Croker, R.; Smyth, D.; Walker, A.; Goldacre, B.

10.1101/266403 — epidemiology — Posted on 2018-02-17

788 An Adaptive Flagellar Photoresponse Determines the Dynamics of Accurate Phototactic Steering in Chlamydomonas

Leptos, K. C.; Chioccioli, M.; Furlan, S.; Pesci, A. I.; Goldstein, R. E.

10.1101/254714 — biophysics — Posted on 2018-02-17

789 Log D Analysis using Dynamic Approach

Krishnamoorthy, G. K. P.; Alluvada, P.; Alemayehu, E.; Hameed MS, S.; Alemayehu, W.; Kwa, T.; Krishnamoorthy, J.

10.1101/259770 — biophysics — Posted on 2018-02-17

790 Assessment of an organ-specific de novo transcriptome of the nematode trap-crop, Solanum sisymbriifolium

Wixom, A. Q.; Casavant, C.; Kuhl, J. C.; Xiao, F.; Dandurand, L.-M.; Caplan, A. B.

10.1101/256065 — bioinformatics — Posted on 2018-02-17

791 Multi-modal brain fingerprinting: a manifold approximation based framework

Kumar, K.; Chauvin, L.; Toews, M.; Colliot, O.; Desrosiers, C.

10.1101/209726 — neuroscience — Posted on 2018-02-17

792 Landscape of gene transposition-duplication within the Brassicaceae family

Oh, D.-H.; Dassanayake, M.

10.1101/236299 — genomics — Posted on 2018-02-17

793 Shared Genetic Contributions to Atrial Fibrillation and Ischemic Stroke Risk

Pulit, S. L.; Weng, L.-C.; McArdle, P. F.; Trinquart, L.; Huan Choi, S.; Mitchell, B. D.; Rosand, J.; de Bakker, P. I.; Benjamin, E. J.; Ellinor, P. T.; Kittner, S. J.; Lubitz, S. A.; Anderson, C. D.; Atrial Fibrillation Genetics Consortium, ; International Stroke Genetics Consortium,

10.1101/239269 — genetics — Posted on 2018-02-17

794 Gene Regulatory Divergence Between Locally Adapted Ecotypes in Their Native Habitats

Gould, B. A.; Chen, Y.; Lowry, D. B.

10.1101/145805 — evolutionary biology — Posted on 2018-02-17

795 Genomic imprinting mediates dosage compensation in a young plant XY system

Muyle, A.; Zemp, N.; Fruchard, C.; Cegan, R.; Vrana, J.; Deschamps, C.; Tavares, R.; Picard, F.; Hobza, R.; Widmer, A.; Marais, G.

10.1101/179044 — evolutionary biology — Posted on 2018-02-17

796 Tissue-specific activities of the Fat1 cadherin cooperate to control neuromuscular morphogenesis

Helmbacher, F.

10.1101/207308 — developmental biology — Posted on 2018-02-17

797 DNA sequence context controls the binding and processivity of T7 DNA primase

Afek, A.; Ilic, S.; Horton, J.; Lukatsky, D.; Gordan, R.; Akabayov, B.

10.1101/266924 — biophysics — Posted on 2018-02-17

798 PhysiBoSS: a multi-scale agent based modelling framework integrating physical dimension and cell signalling

Letort, G.; Montagud, A.; Stoll, G.; Heiland, R.; Barillot, E.; Macklin, P.; Zinovyev, A.; Calzone, L.

10.1101/267070 — systems biology — Posted on 2018-02-17

799 Investigation of Electrical Stimulation Effect on Intracellular Calcium Dynamics Using Locally Uniform Mesh Refinement

Oftadeh, M. O.

10.1101/267294 — systems biology — Posted on 2018-02-17

800 Detection and Degradation of Nonsense-mediated mRNA Decay Substrates Involve Two Distinct Upf1-bound Complexes

Dehecq, M.; Decourty, L.; Namane, A.; Proux, C.; Kanaan, J.; Le Hir, H.; Jacquier, A.; Saveanu, C.

10.1101/266833 — molecular biology — Posted on 2018-02-16

801 Atomic model of microtubule-bound tau

Kellogg, E. H.; Hejab, N. M. A.; Poepsel, S.; Downing, K. H.; DiMaio, F.; Nogales, E.

10.1101/267153 — molecular biology — Posted on 2018-02-16

802 Myosin1D is an evolutionarily conserved determinant of animal Left/Right asymmetry

Juan, T.; Geminard, C.; Coutelis, J.-B.; Cerezo, D.; Poles, S.; Noselli, S.; Fürthauer, M.

10.1101/267146 — developmental biology — Posted on 2018-02-16

803 Prospective identification of cross-reactive human peptide-MHC ligands for T cell receptor based therapies

Gejman, R. S.; Klatt, M. G.; Chang, A. Y.; Jones, H. F.; Oh, C. Y.; Chandran, S. S.; Korontsvit, T.; Zakahleva, V.; Dao, T.; Klebanoff, C. A.; Scheinberg, D. A.

10.1101/267047 — cancer biology — Posted on 2018-02-16

804 Regulation of ATR activity by the RNA polymerase II phosphatase PNUTS-PP1

Landsverk, H. B.; Sandquist, L. E.; Rodland, G. E.; Grallert, B.; Trinkle-Mulcahy, L.; Syljuasen, R. G.

10.1101/267013 — cancer biology — Posted on 2018-02-16

805 Quantifying configuration-sampling error in Langevin simulations of complex molecular systems

Fass, J.; Sivak, D.; Crooks, G. E.; Beauchamp, K. A.; Leimkuhler, B.; Chodera, J.

10.1101/266619 — biophysics — Posted on 2018-02-16

806 DeepLoco: Fast 3D Localization Microscopy Using Neural Networks

Boyd, N.; Jonas, E.; Babcock, H. P.; Recht, B.

10.1101/267096 — biophysics — Posted on 2018-02-16

807 A fully automatic method yielding initial models from high-resolution electron cryo-microscopy maps

Terwilliger, T. C.; Adams, P. D.; Afonine, P. V.; Sobolev, O. V.

10.1101/267138 — biochemistry — Posted on 2018-02-16

808 Mavacamten stabilizes a folded-back sequestered super-relaxed state of β-cardiac myosin

Anderson, R. L.; Trivedi, D. V.; Sarkar, S. S.; Henze, M.; Ma, W.; Gong, H.; Rogers, C. S.; Wong, F. L.; Morck, M.; Ruppel, K. M.; Irving, T. C.; Cooke, R.; Green, E. M.; Spudich, J. A.

10.1101/266783 — biochemistry — Posted on 2018-02-16

809 Control of mRNA decapping by autoinhibition

Paquette, D. R.; Tibble, R. W.; Daifuku, T. S.; Gross, J. D.

10.1101/266718 — biochemistry — Posted on 2018-02-16

810 Stress response of Chironomus riparius to changes in water temperature and oxygen concentration in a lowland stream

Manfrin, A.; Larsen, S.; Scalici, M.; Wurtz, S.; Monaghan, M. T.

10.1101/266528 — zoology — Posted on 2018-02-16

811 Using maximum entropy production to describe microbial biogeochemistry over time and space in a meromictic pond

Vallino, J. J.; Huber, J. A.

10.1101/266346 — systems biology — Posted on 2018-02-16

812 Sequence-directed action of RSC remodeler and pioneer factors positions +1 nucleosome to facilitate transcription

Kubik, S.; O'Dubhuir, E.; de Jonge, W.; Mattarocci, S.; Albert, B.; Falcone, J.-L.; Bruzzone, M. J.; Holstege, F. C. P.; Shore, D.

10.1101/266072 — molecular biology — Posted on 2018-02-16

813 Aberrant mast cell activation promotes chronic recurrent multifocal osteomyelitis

Lee, J. H. P.; Sharma, N.; Young, S.; Chitu, V.; Henkelman, M.; Neumeister, V.; Sohr, E.; Stanley, E. R.; Hedrich, C. M.; Craig, A.

10.1101/259275 — immunology — Posted on 2018-02-16

814 Emerging Evidence of Chromosome Folding by Loop Extrusion

Fudenberg, G.; Abdennur, N.; Imakaev, M.; Goloborodko, A.; Mirny, L.

10.1101/264648 — genomics — Posted on 2018-02-16

815 Standard operating procedure for somatic variant refinement of tumor sequencing data

10.1101/266262 — genetics — Posted on 2018-02-16

816 A comment on "Species are not most abundant in the center of their geographic range or climatic niche"

Soberon, J.; Peterson, A. T.; Osorio-Olvera, L.

10.1101/266510 — ecology — Posted on 2018-02-16

817 Growth tradeoffs produce complex microbial communities without direct interactions

Manhart, M.; Shakhnovich, E.

10.1101/266569 — ecology — Posted on 2018-02-16

818 Multi-omic tumor data reveal diversity of molecular mechanisms underlying survival

Ramazzotti, D.; Lal, A.; Wang, B.; Batzoglou, S.; Sidow, A.

10.1101/267245 — cancer biology — Posted on 2018-02-16

819 Generation of tumorigenic porcine pancreatic ductal epithelial cells: toward a large animal model of pancreatic cancer

Remmers, N.; Cox, J. L.; Grunkemeyer, J. A.; Aravind, S.; Arkfeld, C. K.; Hollingsworth, M. A.; Carlson, M.

10.1101/267112 — cancer biology — Posted on 2018-02-16

820 Competition in biofilms between cystic fibrosis isolates of Pseudomonas aeruginosa is driven by R-pyocins

Oluyombo, O.; Diggle, S. P.; Penfold, C. N.

10.1101/264580 — microbiology — Posted on 2018-02-16

821 The clinician impact and financial cost to the NHS of litigation over pregabalin: an economic impact analysis

Croker, R.; Smyth, D.; Walker, A.; Goldacre, B.

10.1101/266403 — epidemiology — Posted on 2018-02-16

822 Biochemical Characterization of RecBCD Enzyme from An Antarctic Pseudomonas Species and Identification of Its Cognate Chi (χ) Sequence

Pavankumar, T. L.; Sinha, A. K.; Ray, M. K.

10.1101/266460 — biochemistry — Posted on 2018-02-16

823 Emergence of the erythroid lineage from multipotent hematopoiesis

Khoramian Tusi, B.; Wolock, S. L.; Weinreb, C.; Hwang, Y.; Hidalgo, D.; Zilionis, R.; Waisman, A.; Huh, J.; Klein, A. M.; Socolovsky, M.

10.1101/261941 — systems biology — Posted on 2018-02-16

824 The axon initial segment drives the neuron’s extracellular action potential

Bakkum, D. J.; Radivojevic, M.; Obien, M. E.; Jaeckel, D.; Frey, U.; Takahashi, H.; Hierlemann, A.

10.1101/266734 — neuroscience — Posted on 2018-02-16

825 Stability of representational geometry across a wide range of fMRI activity levels

Arbuckle, S. A.; Yokoi, A.; Pruszynski, J. A.; Diedrichsen, J.

10.1101/266585 — neuroscience — Posted on 2018-02-16

826 Liquefaction of the brain following stroke shares a similar molecular and morphological profile with atherosclerosis and mediates secondary neurodegeneration in an osteopontin dependent mechanism

Chung, A.; Frye, J.; Zbesko, J. C.; Constantopoulos, E.; Hayes, M. I.; Figueroa, A. G.; Day, W. A.; Konhilas, J. P.; McKay, B. S.; Nguyen, T.-V. V.; Doyle, K. P.

10.1101/264275 — neuroscience — Posted on 2018-02-16

827 High prevalence of the antibody against Syncytin-1 in schizophrenia

Hibi, Y.; Asamitsu, K.; Matsumura, H.; Sanda, T.; Nakahira, Y.; Arimoto, K.; Nakanishi, S.; Maekawa, K.; Akechi, T.; Matsukawa, N.; Fukaya, T.; Tomita, Y.; Iijima, N.; Kato, H.; Okamoto, T.

10.1101/266049 — neuroscience — Posted on 2018-02-16

828 Swedish Nerve Growth Factor Mutation (NGFR100W) Defines a Role for TrkA and p75NTR in Nociception

Sung, K.; Ferrari, L. F.; Yang, W.; Chung, C.; Zhao, X.; Gu, Y.; Lin, S.; Zhang, K.; Cui, B.; Pearn, M. L. P. L.; Maloney, M. T.; Mobley, W. C.; Levine, J. D.; Wu, C.

10.1101/266643 — neuroscience — Posted on 2018-02-16

829 Liquid co-substrates repower sewage microbiomes

Hardegen, J.; Latorre-Perez, A.; Vilanova, C.; Gunther, T.; Simeonov, C.; Porcar, M.; Luschnig, O.; Abendroth, C.

10.1101/261339 — microbiology — Posted on 2018-02-16

830 Repeated imitation makes human vocalizations more word-like

Edmiston, P.; Lupyan, G.; Perlman, M.

10.1101/149708 — evolutionary biology — Posted on 2018-02-16

831 Reverse immunodynamics: a new method to identifying targets of protective immunity.

Lourenco, J.; Spensley, K. J.; Wikramaratna, P. S.; Penman, B. S.; Walker, A.; Smith, A. L.; Pybus, O. G.; Jean, L.; Gupta, S.

10.1101/159483 — epidemiology — Posted on 2018-02-16

832 FDAAA TrialsTracker: A live informatics tool to monitor compliance with FDA requirements to report clinical trial results

DeVito, N. J.; Bacon, S.; Goldacre, B.

10.1101/266452 — clinical trials — Posted on 2018-02-16

833 Characterizing protein-DNA binding event subtypes in ChIP-exo data

Yamada, N.; Lai, W. K.; Farrell, N.; Pugh, B. F.; Mahony, S.

10.1101/266536 — bioinformatics — Posted on 2018-02-16

834 Information synergy: adding unambiguous quality information rescues social information use in ants

Czaczkes, T. J.; Beckwith, J. J.

10.1101/219980 — animal behavior and cognition — Posted on 2018-02-16

835 CRISPR-based editing reveals edge-specific effects in biological networks

Li, Y.; Nowak, C.; Withers, D.; Pertsemlidis, A.; Bleris, L.

10.1101/265710 — systems biology — Posted on 2018-02-16

836 Single-Nucleotide-Resolution Computing and Memory in Living Cells

Farzadfard, F.; Gharaei, N.; Higashikuni, Y.; Jung, G.; Cao, J.; Lu, T. K.

10.1101/263657 — synthetic biology — Posted on 2018-02-16

837 Anamorphic development and extended parental care in a 520 million-year-old stem-group euarthropod from China

Fu, D.; Ortega-Hernandez, J.; Daley, A.; Zhang, X.; Degan, S.

10.1101/266122 — paleontology — Posted on 2018-02-16

838 DLPFC Transcriptome Defines Two Molecular Subtypes of Schizophrenia

Rhodes, C. H.; Bowen, E. F. W.; Burgess, J. L.; Granger, R.

10.1101/116699 — neuroscience — Posted on 2018-02-16

839 Significant shared heritability underlies suicide attempt and clinically predicted probability of attempting suicide

Ruderfer, D. M.; Walsh, C. G.; Aguirre, M. W.; Ribeiro, J. D.; Franklin, J. C.; Rivas, M. A.

10.1101/266411 — genomics — Posted on 2018-02-16

840 Meta-analyses identify differentially expressed microRNAs in Parkinson’s disease

Schulz, J.; Takousis, P.; Wohlers, I.; Itua, I.; Dobricic, V.; Binder, H.; Middleton, L.; Ioannidis, J.; Perneczky, R.; Bertram, L.; Lill, C.

10.1101/253849 — genetics — Posted on 2018-02-16

841 In search of the Goldilocks zone for hybrid speciation

Blanckaert, A.; Bank, C.

10.1101/266254 — evolutionary biology — Posted on 2018-02-16

842 The integrated stress response regulates BMP signaling through effects on translation

Malzer, E.; Dominicus, C. S.; Chambers, J. E.; Mookerjee, S.; Marciniak, S. J.

10.1101/266189 — cell biology — Posted on 2018-02-16

843 Network Dynamics of ER-α activation reveals reprogramming of GRHL2

Holding, A.; Giorgi, F. M.; Donnelly, A.; Cullen, A. E.; Selth, L. A.; Markowetz, F.

10.1101/266908 — cancer biology — Posted on 2018-02-16

844 Integrated molecular, clinical, and ontological analysis identifies overlooked disease relationships

Haynes, W.; Vashisht, R.; Vallania, F.; Liu, C.; Gaskin, G. L.; Bongen, E.; Lofgren, S.; Sweeney, T. E.; Utz, P. J.; Shah, N. H.; Khatri, P.

10.1101/214833 — bioinformatics — Posted on 2018-02-16

845 Constriction rate modulation can drive cell size control and homeostasis in C. crescentus

Manley, S.; Lambert, A.; Vanhecke, A.; Archetti, A.; Holden, S.; Schaber, F.; Pincus, Z.; Laub, M. T.; Goley, E. D.

10.1101/266817 — biophysics — Posted on 2018-02-16

846 Ultra-fast cellular contractions in the epithelium of T. adhaerens and the "active cohesion" hypothesis

Armon, S.; Bull, M. S.; Aranda-Diaz, A. J.; Prakash, M.

10.1101/258103 — biophysics — Posted on 2018-02-16

847 DNA sequence context controls the binding and processivity of T7 DNA primase

Afek, A.; Ilic, S.; Horton, J.; Lukatski, D.; Gordan, R.; Akabayov, B.

10.1101/266924 — biophysics — Posted on 2018-02-16

848 A mechanism for the proliferative control of tissue mechanics in the absence of growth

Wu, M.; Mani, M.

10.1101/266577 — developmental biology — Posted on 2018-02-16

849 tarsal-less is expressed as a gap gene but has no gap gene phenotype in the moth midge Clogmia albipunctata.

jimenez-guri, e.; Wotton, K.; Jaeger, J.

10.1101/266288 — developmental biology — Posted on 2018-02-16

850 BAX requires VDAC2 to mediate apoptosis and to limit tumor development

Chin, H. S.; van Delft, M. F.; Ninnis, R. L.; Mark, L. X.; Tan, I. K.; Reljic, B.; Scicluna, K.; Dagley, L. F.; Sandow, J. J.; Kelly, G. L.; Chappaz, S.; Khaw, S. L.; Chang, C.; Webb, A.; Hockings, C.; Hall, C.; Kueh, A.; Ryan, M. T.; Kluck, R. M.; Bouillet, P.; Herold, M. J.; Gray, D. H.; Huang, D. C.; Dewson, G.

10.1101/266668 — cell biology — Posted on 2018-02-16

851 Control of flagellum length by a grow-and-lock model

Bertiaux, E.; Morga, B.; Blisnick, T.; Rotureau, B.; Bastin, P.

10.1101/266759 — cell biology — Posted on 2018-02-16

852 Cell growth rate dictates the onset of glass to fluid-like transition and long time super-diffusion in an evolving cell colony

Malmi-Kakkada, A. N.; Li, X.; Samanta, H. S.; Sinha, S.; Thirumalai, D.

10.1101/174599 — biophysics — Posted on 2018-02-15

853 Evolution transforms pushed waves into pulled waves

Erm, P.; Phillips, B. L.

10.1101/266007 — ecology — Posted on 2018-02-15

Koen, J. D.; Horne, E. D.; Hauck, N.; Rugg, M. D.

10.1101/188664 — neuroscience — Posted on 2018-02-15

855 Dynamics of brain activity reveal a unitary recognition signal

Weidemann, C. T.; Kahana, M. J.

10.1101/165225 — neuroscience — Posted on 2018-02-15

856 The virome of Drosophila suzukii, an invasive pest of soft fruit

Medd, N. C.; Fellous, S.; Waldron, F. M.; Nakai, M.; Xuereb, A.; Cross, J. V.; Obbard, D. J.

10.1101/190322 — microbiology — Posted on 2018-02-15

857 Yellow fever virus is susceptible to sofosbuvir both in vitro and in vivo

de Freitas, C.; Higa, L.; Sacramento, C.; Ferreira, A.; Reis, P.; Delvecchio, R.; Monteiro, F.; Barbosa-Lima, G.; Vieira, Y.; Mattos, M.; Hoelz, L.; Leme, R.; Bastos, M.; Bozza, F.; Bozza, P.; Boechat, N.; Tanuri, A.; Souza, T.

10.1101/266361 — microbiology — Posted on 2018-02-15

858 Genetic variants associated with Alzheimer's disease confer different cerebral cortex cell-type population structure

Li, Z.; Del Aguila, J. L.; Dube, U.; Budde, J.; Martinez, R.; Black, K.; Xiao, Q.; Cairns, N. J.; Dominantly Inherited Alzheimer Network (DIAN), ; Dougherty, J. D.; Lee, J.-M.; Morris, J. C.; Bateman, R. J.; Karch, C. M.; Cruchaga, C.; Harari, O.

10.1101/266296 — genetics — Posted on 2018-02-15

859 Rab-mediated trafficking in the secondary cells of Drosophila male accessory glands and its role in fecundity

Prince, E.; Brankatschk, M.; Kroeger, B.; Wilson, C.; Gligorov, D.; Eaton, S.; Karch, F.; Maeda, R. K.

10.1101/266353 — cell biology — Posted on 2018-02-15

860 Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1

Ehlen, A.; Martin, C.; Julien, M.; Miron, S.; Theillet, F. X.; Boucherit, V.; Duchambon, P.; El Marjou, A.; Zinn Justin, S.; Carreira, A.

10.1101/265934 — cell biology — Posted on 2018-02-15

861 PET by MRI: Glucose Imaging by 13C-MRS without Dynamic Nuclear Polarization by Noise Suppression through Tensor Decomposition Rank Reduction

Brender, J. R.; Kishimoto, S.; Merkle, H.; Reed, G.; Hurd, R. E.; Chen, A. P.; Ardenkjaer-Larsen, J. H.; Munasinghe, J.; Saito, K.; Seki, T.; Oshima, N.; Yamamoto, K.; Choyke, P. L.; Mitchell, J.; Krishna, M. C.

10.1101/265793 — cancer biology — Posted on 2018-02-15

862 HISAT-genotype: Next Generation Genomic Analysis Platform on a Personal Computer

Kim, D.; Paggi, J. M.; Salzberg, S.

10.1101/266197 — bioinformatics — Posted on 2018-02-15

863 GeneQC: A quality control tool for gene expression estimation based on RNA-sequencing reads mapping

McDermaid, A.; Chen, X.; Zhang, Y.; Xie, J.; Wang, C.; Ma, Q.

10.1101/266445 — bioinformatics — Posted on 2018-02-15

864 NanoPack: visualizing and processing long read sequencing data

De Coster, W.; D'Hert, S.; Schultz, D. T.; Cruts, M.; Van Broeckhoven, C.

10.1101/237180 — bioinformatics — Posted on 2018-02-15

865 Biochemical Characterization of RecBCD Enzyme from An Antarctic Pseudomonas Species and Identification of Its Cognate Chi (χ) Sequence

Pavankumar, T. L.; Sinha, A. K.; Ray, M. K.

10.1101/266460 — biochemistry — Posted on 2018-02-15

866 Single-Nucleotide-Resolution Computing and Memory in Living Cells

Farzadfard, F.; Gharaei, N.; Higashikuni, Y.; Jung, G.; Cao, J.; Lu, T. K.

10.1101/263657 — synthetic biology — Posted on 2018-02-15

867 Reversion of the photoperiod dependence of flowering in rice with synthetic Hd1-microProteins

Eguen, T.; Gomez Ariza, J.; Bhati, K.; Sun, B.; Fornara, F.; Wenkel, S.

10.1101/266486 — plant biology — Posted on 2018-02-15

868 The Constriction Ring of Amniotic Band Syndrome Reveals Idiosyncrasies of Wound Repair in Infancy

Bhattacharyya, S. N.; Ilyashov, I. M.; Chu, A.

10.1101/266478 — pathology — Posted on 2018-02-15

869 The cortical dynamics orchestrating skilled prehension

Sauerbrei, B.; Guo, J.-Z.; Zheng, J.; Guo, W.; Kabra, M.; Verma, N.; Branson, K.; Hantman, A.

10.1101/266320 — neuroscience — Posted on 2018-02-15

870 Nanoscale colocalization of NK cell activating and inhibitory receptors controls signal integration

Tomaz, D.; Pereira, P. M.; Guerra, N.; Dyson, J.; Henriques, R.; Gould, K.

10.1101/266429 — immunology — Posted on 2018-02-15

871 Significant shared heritability underlies suicide attempt and clinically predicted probability of attempting suicide

Ruderfer, D. M.; Walsh, C. G.; Aquirre, M. W.; Ribeiro, J. D.; Franklin, J. C.; Rivas, M. A.

10.1101/266411 — genomics — Posted on 2018-02-15

872 Information Isometry Technique Reveals Organizational Features in Developmental Cell Lineages

Alicea, B. J.; Portegys, T. E.; Gordon, R.

10.1101/062539 — developmental biology — Posted on 2018-02-15

873 pyseer: a comprehensive tool for microbial pangenome-wide association studies

Lees, J.; Galardini, M.; Bentley, S. D.; Weiser, J. N.; Corander, J.

10.1101/266312 — bioinformatics — Posted on 2018-02-15

874 GenoGAM 2.0: Scalable and efficient implementation of genome-wide generalized additive models for gigabase-scale genomes

Stricker, G.; Galinier, M.; Gagneur, J.

10.1101/265595 — bioinformatics — Posted on 2018-02-15

875 Engineering bacteria for biogenic synthesis of chalcogenide nanomaterials

Boedicker, J. Q.; Chellamuthu, P.; Tran, F.; Silva, P.; El Naggar, M.

10.1101/266502 — bioengineering — Posted on 2018-02-15

876 Modeling Uncertainty in Grapevine Powdery Mildew Epidemiology Using Fuzzy Logic

Choudhury, R. A.; Mahaffee, W.; McRoberts, N.; Gubler, W. D.

10.1101/264622 — epidemiology — Posted on 2018-02-15

877 Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies

10.1101/260281 — systems biology — Posted on 2018-02-15

878 CRISPR-based editing reveals edge-specific effects in biological networks

Li, Y.; Nowak, C.; Withers, D.; Pertsemlidis, A.; Bleris, L.

10.1101/265710 — systems biology — Posted on 2018-02-15

879 Escherichia coli can survive stress by noisy growth modulation

Patange, O.; Schwall, C.; Jones, M.; Griffith, D.; Phillips, A.; Locke, J.

10.1101/265801 — systems biology — Posted on 2018-02-15

880 Crowdsourcing Image Analysis for Plant Phenomics to Generate Ground Truth Data for Machine Learning

Siegel, Z. D.; Zhou, N.; Zarecor, S.; Lee, N.; Campbell, D. A.; Andorf, C. M.; Nettleton, D.; Lawrence-Dill, C. J.; Ganapathysubramanian, B.; Friedberg, I.; Kelly, J. W.

10.1101/265918 — plant biology — Posted on 2018-02-15

881 3D Axonal Morphometry of White Matter

Abdollahzadeh, A.; Belevich, I.; Jokitalo, E.; Tohka, J.; Sierra, A.

10.1101/239228 — neuroscience — Posted on 2018-02-15

882 From categories to dimensions: spatio-temporal dynamics of the cerebral representations of emotion in voice

Giordano, B. L.; Whiting, C.; Kriegeskorte, N.; Kotz, S. A.; Belin, P.; Gross, J.

10.1101/265843 — neuroscience — Posted on 2018-02-15

883 Co-modulation of synapses and voltage-gated ionic currents by combined actions of multiple neuromodulators follow distinct rules

Li, X.; Bucher, D. M.; Nadim, F.

10.1101/265694 — neuroscience — Posted on 2018-02-15

884 Template-based prediction of vigilance fluctuations in resting-state fMRI

Falahpour, M.; Chang, C.; Wong, C. W.; Liu, T.

10.1101/234179 — neuroscience — Posted on 2018-02-15

885 A common goodness-of-fit framework for neural population models using marked point process time-rescaling

Tao, L.; Weber, K.; Arai, K.; Eden, U.

10.1101/265850 — neuroscience — Posted on 2018-02-15

886 The signaling lipid sphingosine 1-phosphate regulates mechanical pain

Hill, R. Z.; Hoffman, B. U.; Morita, T.; Campos, S. M.; Lumpkin, E. A.; Brem, R. B.; Bautista, D. M.

10.1101/236778 — neuroscience — Posted on 2018-02-15

887 Live cell monitoring of double strand breaks in S. cerevisiae

Waerman, D. P.; Lee, C.-S.; Tsabar, M.; Zhou, F.; Eapen, V. V.; Mazzella, A. J.; Haber, J. E.

10.1101/265611 — molecular biology — Posted on 2018-02-15

888 An Escherichia coli nitrogen starvation response is important for mutualistic coexistence with Rhodopseudomonas palustris

McCully, A. L.; Behringer, M. G.; Gliessman, J. R.; Pilipenko, E. V.; Mazny, J. L.; Lynch, M.; Drummond, D. A.; McKinlay, J. B.

10.1101/262139 — microbiology — Posted on 2018-02-15

889 Yellow Fever, Dengue Fever And West Nile Viruses Co-Circulation In Ogbomoso

Oladipo, E. K.; Olke, J. K.; Awoyelu, E. H.

10.1101/265819 — microbiology — Posted on 2018-02-15

890 A stainless-steel mortar, pestle and sleeve design for the efficient fragmentation of ancient bone

Gondek, A. T.; Boessenkool, S.; Star, B.

10.1101/265587 — genomics — Posted on 2018-02-15

891 Hybrid de novo assembly of the draft genome of the freshwater mussel Venustaconcha ellipsiformis (Bivalvia: Unionida).

Renaut, S.; Guerra, D.; Hoeh, W.; Stewart, D.; Bogan, A.; Ghiselli, F.; Milani, L.; Passamonti, M.; Breton, S.

10.1101/265157 — genomics — Posted on 2018-02-15

892 Age distributions of rare lineages reveal recent demographic history and selection

Platt, A.; Hey, J.

10.1101/265900 — genomics — Posted on 2018-02-15

893 H3K4 methylation dependent and independent chromatin regulation by JHD2 and SET1 in budding yeast

Meneghini, M.; Lee, K. Y.; Jiang, R.; Chen, Z.

10.1101/265926 — genetics — Posted on 2018-02-15

894 Ablation of Ezh2 in neural crest cells leads to Hirschsprung's disease-like phenotype in mice

Kim, J.; Kim, H.; Langohr, I. M.; Faisal, M.; McNulty, M.; Thorn, C.

10.1101/265868 — genetics — Posted on 2018-02-15

895 High accuracy haplotype-derived allele frequencies from ultra-low coverage pool-seq samples

Tilk, S.; Bergland, A. O.; Goodman, A.; Schmidt, P.; Petrov, D.; Greenblum, S.

10.1101/244004 — evolutionary biology — Posted on 2018-02-15

896 Estimating the impact of city-wide Aedes aegypti population control: An observational study in Iquitos, Peru

Reiner, R.; Stoddard, S.; Vazquez-Prokopec, G.; Astete, H.; Perkins, T. A.; Sihuincha, M.; Stancil, J.; Smith, D.; Kochel, T.; Halsey, E.; Kitron, U.; Morrison, A.; Scott, T.

10.1101/265751 — ecology — Posted on 2018-02-15

897 Spatial Capture-Recapture for Categorically Marked Populations with An Application to Genetic Capture-Recapture

Augustine, B.; Royle, J. A.; Murphy, S.; Chandler, R.; Cox, J.; Kelly, M.

10.1101/265678 — ecology — Posted on 2018-02-15

898 Massive surface membrane expansion without involvement of classical exocytic mechanisms.

Fine, M.; Bricogne, C.; Hilgemann, D. W.

10.1101/249284 — cell biology — Posted on 2018-02-15

899 A ZIP1 Separation-of-Function Allele Reveals that Meiotic Centromere Pairing Drives Meiotic Segregation of Achiasmate Chromosomes in Budding Yeast

Kurdzo, E. L.; Chuong, H. H.; Dawson, D. S.

10.1101/265652 — cell biology — Posted on 2018-02-15

900 Persistent cell motility requires transcriptional feedback of cytoskeletal - focal adhesion equilibrium by YAP/TAZ

Mason, D. E.; Dawahare, J. H.; Nguyen, T. D.; Lin, Y.; Voytik-Harbin, S. L.; Zorlutuna, P.; Yoder, M. E.; Boerckel, J. D.

10.1101/265744 — cell biology — Posted on 2018-02-15

901 Immune evasion and immunotherapy resistance via TGF-beta activation of extracellular matrix genes in cancer associated fibroblasts

Chakravarthy, A.; Khan, L.; Bensler, N. P.; Bose, P.; De Carvalho, D. D.

10.1101/265884 — cancer biology — Posted on 2018-02-15

902 PET by MRI: Glucose Imaging by 13C-MRS without Dynamic Nuclear Polarization by Noise Suppression through Tensor Decomposition Rank Reduction

10.1101/265793 — cancer biology — Posted on 2018-02-15

903 Uniform Resolution of Compact Identifiers for Biomedical Data

Wimalaratne, S.; Juty, N.; Kunze, J.; Janee, G.; McMurry, J. A.; Beard, N.; Jimenez, R.; Grethe, J.; Hermjakob, H.; Clark, T.

10.1101/101279 — bioinformatics — Posted on 2018-02-15

904 Modeling brain dynamics in brain tumor patients using The Virtual Brain

Aerts, H.; Schirner, M.; Jeurissen, B.; Van Roost, D.; Achten, E.; Ritter, P.; Marinazzo, D.

10.1101/265637 — bioinformatics — Posted on 2018-02-15

905 Enhancer Identification using Transfer and Adversarial Deep Learning of DNA Sequences

Cohn, D.; Zuk, O.; Kaplan, T.

10.1101/264200 — bioinformatics — Posted on 2018-02-15

906 The Sibship Index can’t discriminates Half-Sibs from Full-Sibs; a new algorithm, including maternal genotype, can do it

Cardillo, G.

10.1101/265561 — bioinformatics — Posted on 2018-02-15

907 Regressions fit for purpose: Models of locust phase state must not conflate morphology with behaviour

Ott, S. R.

10.1101/174763 — animal behavior and cognition — Posted on 2018-02-15

908 Decision by sampling implements efficient coding of psychoeconomic functions

Bhui, R.; Gershman, S. J.

10.1101/220277 — animal behavior and cognition — Posted on 2018-02-15

909 Double-digest RAD sequencing outperforms microsatellite loci at assigning paternity and estimating relatedness: a proof of concept in a highly promiscuous bird

Thrasher, D. J.; Butcher, B. G.; Campagna, L.; Webster, M. S.; Lovette, I. J.

10.1101/169144 — animal behavior and cognition — Posted on 2018-02-15

910 The upstrap

Crainiceanu, C.

10.1101/262436 — epidemiology — Posted on 2018-02-15

911 Downgrading disease transmission risk estimates using terminal importations

Fox, S. J.; Bellan, S. E.; Perkins, T. A.; Johansson, M. A.; Meyers, L. A.

10.1101/265942 — epidemiology — Posted on 2018-02-15

912 Epidemiological Study of Autism Subgroups Using Autism Treatment Evaluation Checklist (ATEC) Score

Mahapatra, S.; Khokhlovich, E.; Martinez, S.; Kannel, B.; Edelson, S. M.; Vyshedskiy, A.

10.1101/266221 — epidemiology — Posted on 2018-02-15

913 A new paradigm for personalized cancer screening

Walker, R.; Enderling, H.

10.1101/265959 — epidemiology — Posted on 2018-02-15

914 Epigenome-wide association study of placental DNA methylation and maternal exposure to night shift work in the Rhode Island Child Health Study

Clarkson-Townsend, D. A.; Everson, T. M.; Deyssenroth, M. A.; Burt, A. A.; Hermetz, K. E.; Hao, K.; Chen, J.; Marsit, C. J.

10.1101/265777 — epidemiology — Posted on 2018-02-15

915 Cardiovascular Disease Risk Factor Responses to a Type 2 Diabetes Care Model Including Nutritional Ketosis at One Year: An Open Label, Non-Randomized, Controlled Study

Bhanpuri, N. H.; Hallberg, S. J.; Williams, P. T.; McKenzie, A. L.; Ballard, K. D.; Campbell, W. W.; McCarter, J. P.; Phinney, S. D.; Volek, J. S.

10.1101/262709 — clinical trials — Posted on 2018-02-15

916 THEA: A novel approach to gene identification in phage genomes

McNair, K.; Zhou, C.; Souza, B.; Edwards, R.

10.1101/265983 — bioinformatics — Posted on 2018-02-15

917 Triggering the expression of a silent gene cluster from genetically intractable bacteria results in scleric acid discovery

Alberti, F.; Leng, D. J.; Wilkening, I.; Song, L.; Tosin, M.; Corre, C.

10.1101/265645 — synthetic biology — Posted on 2018-02-15

918 SNAP-tagged nanobodies enable reversible optical control of a G protein-coupled receptor via a remotely tethered photoswitchable ligand

Farrants, H.; Acosta Ruiz, A.; Gutzeit, V. A.; Trauner, D.; Johnsson, K.; Levitz, J.; Broichhagen, J.

10.1101/266247 — pharmacology and toxicology — Posted on 2018-02-15

919 Dental erosion caused by a gastrointestinal disorder in a child from the Late Holocene of Northeastern Brazil

Oliveira, R. E.; Solari, A.; Silva, S. F. S. M.; Martin, G.

10.1101/265702 — pathology — Posted on 2018-02-15

920 Anamorphic development and extended parental care in a 520 million-year-old stem-group euarthropod from China

Fu, D.; Hernandez-Ortega, J.; Daley, A.; Zhang, X.; Degan, S.

10.1101/266122 — paleontology — Posted on 2018-02-15

921 Somatic nicotinic acetylcholine receptors control the activity of dopamine neurons and reward-related behaviors.

Durand-de Cuttoli, R.; Mondoloni, S.; Marti, F.; Lemoine, D.; Naude, J.; d'Izarny-Gargas, T.; Pons, S.; Maskos, U.; Trauner, D.; Kramer, R. H.; Faure, P.; Mourot, A.

10.1101/266163 — neuroscience — Posted on 2018-02-15

922 Coordinate based meta-analysis of whole-brain voxel-based morphometry studies does not show evidence of grey matter loss specific to PTSD

Tench, C.; Tanasescu, R.; Jethwa, K.; Constantinescu, C.

10.1101/265496 — neuroscience — Posted on 2018-02-15

923 Feature Specific Prediction Errors and Surprise across Macaque Fronto-Striatal Circuits during Attention and Learning

Oemisch, M.; Westendorff, S.; Azimi, M.; Hassani, S. A.; Ardid, S.; Tiesinga, P.; Womelsdorf, T.

10.1101/266205 — neuroscience — Posted on 2018-02-15

924 Resistance to pentamidine is mediated by AdeAB, regulated by AdeRS, and influenced by growth conditions in Acinetobacter baumannii ATCC 17978

Adams, F. G.; Stroeher, U. H.; Hassan, K. A.; Marri, S.; Brown, M.

10.1101/265520 — microbiology — Posted on 2018-02-15

925 Drosophila melanogaster establishes a species-specific mutualistic interaction with stable gut-colonizing bacteria

Pais, I. S.; Valente, R. S.; Sporniak, M.; Teixeira, L.

10.1101/265991 — microbiology — Posted on 2018-02-15

926 Primate MHC class I from Genomes

Olivieri, D. N.; Gambon-Deza, F.

10.1101/266064 — immunology — Posted on 2018-02-15

927 Medical consequences of pathogenic CNVs in adults: Analysis of the UK Biobank.

Crawford, K.; Bracher-Smith, M.; Kendall, K. M.; Rees, E.; Pardinas, A. F.; Einon, M.; Escott-Price, V.; Walters, J. T.; O'Donovan, M. C.; Owen, M. J.; Kirov, G.

10.1101/264077 — genomics — Posted on 2018-02-15

928 Transcription initiation RNAs are associated with chromatin activation mark H3K4me3

Hobbs, M.; Ender, C.; Baillie, G. J.; Crawford, J.; Ru, K.; Taft, R.; Mattick, J. S.

10.1101/265827 — genomics — Posted on 2018-02-15

929 The Limits to Parapatric Speciation II: Strengthening a Preexisting Genetic Barrier to Gene Flow in Parapatry

Blanckaert, A.; Hermisson, J.

10.1101/266098 — genetics — Posted on 2018-02-15

930 In search of the Goldilocks zone for hybrid speciation

Blanckaert, A.; Bank, C.

10.1101/266254 — evolutionary biology — Posted on 2018-02-15

931 Evolution transforms pushed waves into pulled waves

Erm, P.; Phillips, B. L.

10.1101/266007 — ecology — Posted on 2018-02-15

932 The integrated stress response regulates BMP signaling through effects on translation

Malzer, E.; Dominicus, C. S.; Chambers, J. E.; Mookerjee, S.; Marciniak, S. J.

10.1101/266189 — cell biology — Posted on 2018-02-15

933 ReadFilter - Filtering reads of interest for quicker downstream analysis

Ng, K. L.; Johannesen, T. B.; Osterlund, M.; Kiil, K.; Andersen, P. S.; Stegger, M.

10.1101/266080 — bioinformatics — Posted on 2018-02-15

934 Open Community Challenge Reveals Molecular Network Modules with Key Roles in Diseases

Choobdar, S.; Ahsen, M. E.; Crawford, J.; Tomasoni, M.; Lamparter, D.; Lin, J.; Hescott, B.; Hu, X.; Mercer, J.; Natoli, T.; Narayan, R.; The DREAM Module Identification Challenge Consortium, ; Subramanian, A.; Stolovitzky, G.; Kutalik, Z.; Lage, K.; Slonim, D. K.; Saez-Rodriguez, J.; Cowen, L. J.; Bergmann, S.; Marbach, D.

10.1101/265553 — bioinformatics — Posted on 2018-02-15

935 Building a local community of practice in scientific programming for Life Scientists

Stevens, S. L. R.; Kuzak, M.; Martinez, C.; Moser, A.; Bleeker, P. M.; Galland, M.

10.1101/265421 — scientific communication and education — Posted on 2018-02-15

936 Feeling the force: how pollen tubes deal with obstacles

Burri, J. T.; Vogler, H.; Läubli, N. F.; Hu, C.; Grossniklaus, U.; Nelson, B. J.

10.1101/266106 — plant biology — Posted on 2018-02-15

937 A modular dCas9-SunTag DNMT3A epigenome editing system overcomes pervasive off-target activity of direct fusion dCas9-DNMT3A constructs

Pflueger, C.; Tan, D.; Swain, T.; Nguyen, T. V.; Pflueger, J.; Nefzger, C.; Polo, J. M.; Ford, E.; Lister, R.

10.1101/266130 — molecular biology — Posted on 2018-02-15

938 Structural variation detection by proximity ligation from FFPE tumor tissue

Troll, C.; Putnam, N. H.; Hartley, P. D.; Rice, B.; Blanchette, M.; Siddiqui, S.; Ganbat, J.-O.; Powers, M. P.; Kunder, C. A.; Bustamante, C. D.; Zehnder, J. L.; Green, R. E.; Costa, H. A.

10.1101/266023 — genomics — Posted on 2018-02-15

939 A Genomic Reference Panel for Drosophila serrata

Reddiex, A. R.; Allen, S. L.; Chenoweth, S. F.

10.1101/266031 — genetics — Posted on 2018-02-15

940 Evidence of a common causal relationship between body mass index and inflammatory skin disease: a Mendelian Randomization study

Budu-Aggrey, A.; Brumpton, B.; Tyrrell, J.; Watkins, S.; Modalsli, E. H.; Celis-Morales, C.; Ferguson, L. D.; Vie, G. A.; Palmer, T.; Fritsche, L. G.; Loset, M.; Nielsen, J. B.; Zhou, W.; Tsoi, L. C.; Wood, A. R.; Jones, S. E.; Beaumont, R.; Saunes, M.; Romundstad, P. R.; Siebert, S.; McInnes, I. B.; Elder, J. T.; Smith, G. D.; Frayling, T. M.; Asvold, B. O.; Brown, S. J.; Sattar, N.; Paternoster, L.

10.1101/265629 — genetics — Posted on 2018-02-15

941 Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1

Carreira, A.; Ehlen, A.; Martin, C.; Julien, M.; Miron, S.; Theillet, F. X.; Boucherit, V.; Duchambon, P.; El Marjou, A.; Zinn Justin, S.

10.1101/265934 — cell biology — Posted on 2018-02-15

942 Protein pheromone MUP20/Darcin is a vector and target of indirect genetic effects in mice.

Bachmann, S. O.; Cross, E.; Kalbassi, S.; Sarraf, M. A.; Woodley of Menie, M. A.; Baudouin, S. J. M.

10.1101/265769 — animal behavior and cognition — Posted on 2018-02-15

943 A Model for Resource Competition in CRISPR-Mediated Gene Repression

Chen, P.-Y.; Qian, Y.; Del Vecchio, D.

10.1101/266015 — synthetic biology — Posted on 2018-02-14

944 The proteome of the malaria plastid organelle, a key anti-parasitic target

Boucher, M. J.; Ghosh, S.; Zhang, L.; Lal, A.; Jang, S. W.; Ju, A.; Zhang, S.; Wang, X.; Ralph, S. A.; Zou, J.; Elias, J. E.; Yeh, E.

10.1101/265967 — microbiology — Posted on 2018-02-14

945 Real-time in vivo Global Transcriptional Dynamics During Plasmodium falciparum Blood-stage Development

Painter, H. J.; Chung, N. C.; Sebastian, A.; Albert, I.; Storey, J. D.; Llinas, M.

10.1101/265975 — microbiology — Posted on 2018-02-14

946 PAGE4 and Conformational Switching: Insights from Molecular Dynamics Simulations and Implications for Prostate Cancer

Lin, X.; Roy, S.; Jolly, M. K.; Bocci, F.; Schafer, N.; Tsai, M.-Y.; Kulkarni, P.; Chen, Y.; He, Y.; Orban, J.; Grishaev, A.; Weninger, K.; Rangarajan, G.; Levine, H.; Onuchic, J. N.

10.1101/264010 — biophysics — Posted on 2018-02-14

947 Fanconi Anemia FANCM/FNCM-1 and FANCD2/FCD-2 are required for maintaining histone methylation levels and interact with the histone demethylase LSD1/SPR-5 in C. elegans

Kim, H.-M.; Beese-Sims, S. E.; Colaiacovo, M. P.

10.1101/265876 — genetics — Posted on 2018-02-14

948 An evolutionary-conserved Wnt3/β-catenin/Sp5 feedback loop restricts head organizer activity in Hydra

Vogg, M. C.; Beccari, L.; Iglesias Olle, L.; Rampon, C.; Vriz, S.; Perruchoud, C.; Wenger, Y.; Galliot, B.

10.1101/265785 — developmental biology — Posted on 2018-02-14

949 In vivo clonal analysis reveals spatiotemporal regulation of thalamic nucleogenesis

Wong, S.; Scott, E. P.; Mu, W.; Guo, X.; Borgenheimer, E.; Freeman, M.; Ming, G.-l.; Wu, Q.-F.; Song, H.; Nakagawa, Y.

10.1101/238964 — neuroscience — Posted on 2018-02-14

950 Uncoupling of sgRNAs from their associated barcodes during PCR amplification of combinatorial CRISPR screens

Hegde, M.; Strand, C.; Hanna, R. E.; Doench, J. G.

10.1101/265686 — molecular biology — Posted on 2018-02-14

951 Spatial variation of the native colon microbiota in healthy adults

Flynn, K. J.; Ruffin, M. T.; Turgeon, D. K.; Schloss, P. D.

10.1101/189886 — microbiology — Posted on 2018-02-14

952 A genomic island of Streptomyces coelicolor with the self-contained regulon of an ECF sigma factor

Kao, C. M.; Karoonuthaisiri, N.; Weaver, D.; Vroom, J. A.; Gai, S. A.; Ho, M.-L.; Patel, K. G.

10.1101/247056 — microbiology — Posted on 2018-02-14

953 A widespread decrease of chromatin accessibility in age-related macular degeneration

Wang, J.; Zibetti, C.; Shang, P.; Sripathi, S. R.; Zhang, P.; Cano, M.; Hoang, T.; Xia, S.; Ji, H.; Merbs, S. L.; Zack, D. J.; Handa, J. T.; Sinha, D.; Blackshaw, S.; Qian, J.

10.1101/264564 — genomics — Posted on 2018-02-14

954 Data mining of digitized health records in a resource-constrained setting reveals that timely immunophenotyping is associated with improved breast cancer outcomes

Lopez Pineda, A.; Rodriguez Moran, M. F.; Alvarez Aguilar, C.; Fuentes Valle, S. M.; Acosta Rosales, R.; Bhatt, A. S.; Sheth, S. N.; Bustamante, C. D.

10.1101/198721 — epidemiology — Posted on 2018-02-14

955 Measuring the self-assembly kinetics of individual viral capsids

Garmann, R. F.; Goldfain, A. M.; Manoharan, V. N.

10.1101/265330 — biophysics — Posted on 2018-02-14

956 Identification of transcriptional signatures for cell types from single-cell RNA-Seq

Ntranos, V.; Yi, L.; Melsted, P.; Pachter, L.

10.1101/258566 — bioinformatics — Posted on 2018-02-14

957 False discovery rate estimation and heterobifunctional cross-linkers

Fischer, L.; Rappsilber, J.

10.1101/239715 — bioinformatics — Posted on 2018-02-14

958 Differences In Neural Activity, But Not Behavior, Across Social Contexts In Guppies, Poecilia reticulata

Fischer, E. K.; Westrick, S. E.; Hartsough, L.; Hoke, K. L.

10.1101/265736 — animal behavior and cognition — Posted on 2018-02-14

959 Sent to the Corner: xylem vessel anatomy not surface area determines megaphyll hydraulics in Cecropia obtusa Trecul (Urticaceae)

Levionnois, S.; Coste, S.; Nicolini, E.; Stahl, C.; Morel, H.; Heuret, P.

10.1101/259036 — plant biology — Posted on 2018-02-14

960 Enhancing resolution of natural methylome reprogramming behavior in plants

Sanchez, R.; Yang, X.; Kundariya, H.; Barreras, J. R.; Wamboldt, Y.; Mackenzie, S.

10.1101/252106 — genomics — Posted on 2018-02-14

961 The predictability of genomic changes underlying a recent host shift in Melissa blue butterflies

Chaturvedi, S.; Lucas, L. K.; Nice, C. C.; Fordyce, J. A.; Forister, M. L.; Gompert, Z.

10.1101/222703 — evolutionary biology — Posted on 2018-02-14

962 An optimized pipeline for parallel image-based quantification of gene expression and genotyping after in situ hybridization

Dobrzycki, T.; Krecsmarik, M.; Bonkhofer, F.; Patient, R. K.; Monteiro, R.

10.1101/149591 — developmental biology — Posted on 2018-02-14

963 Delayed activation of the DNA replication licensing system in Lgr5(+) intestinal stem cells

Carroll, T.; Newton, I.; Chen, Y.; Blow, J. J.; Nathke, I.

10.1101/177477 — cell biology — Posted on 2018-02-14

964 LinearFold: Linear-Time Prediction of RNA Secondary Structures

Deng, D.; Zhao, K.; Hendrix, D.; Mathews, D.; Huang, L.

10.1101/263509 — bioinformatics — Posted on 2018-02-14

965 Accurate analysis of genuine CRISPR editing events with ampliCan

Labun, K.; Guo, X.; Chavez, A.; Church, G.; Gagnon, J. A.; Valen, E.

10.1101/249474 — bioinformatics — Posted on 2018-02-14

966 Mitigating the lack of knowledge about long noncoding RNA: extracting biological functions

Adam, Y. A. I.; Ruiz, E. E. S.; Macedo, A. A.

10.1101/258343 — bioinformatics — Posted on 2018-02-14

967 Modelling the effects of bacterial cell state and spatial location on tuberculosis treatment: Insights from a hybrid multiscale cellular automaton model

Bowness, R.; Chaplain, M. A. J.; Powathill, G. G.; Gillespie, S. H.

10.1101/059113 — microbiology — Posted on 2018-02-14

968 A Bayesian Framework for Estimating Cell Type Composition from DNA Methylation Without the Need for Methylation Reference

Rahmani, E.; Schweiger, R.; Shenhav, L.; Wingert, T.; Hofer, I.; Gabel, E.; Eskin, E.; Halperin, E.

10.1101/112417 — bioinformatics — Posted on 2018-02-14

969 A functional landscape of chronic kidney disease entities from public transcriptomic data

Tajti, F.; Antoranz, A.; Ibrahim, M. M.; Kim, H.; Ceccarelli, F.; Kuppe, C.; Alexopoulos, L. G.; Kramann, R.; Saez-Rodriguez, J.

10.1101/265447 — pathology — Posted on 2018-02-14

970 Cardiovascular risk factors for micro- and macro-structural brain changes in healthy ageing

Fuhrmann, D.; Nesbitt, D.; Shafto, M.; Rowe, J. B.; Price, D.; Gadie, A.; Cam-CAN, ; Kievit, R. A.

10.1101/264770 — neuroscience — Posted on 2018-02-14

971 Population coupling predicts the plasticity of stimulus responses in cortical circuits

Sweeney, Y.; Clopath, C.

10.1101/265041 — neuroscience — Posted on 2018-02-14

972 Variation among intact tissue samples reveals the core transcriptional features of human CNS cell classes

Kelley, K. W.; Inoue, H.; Molofsky, A. V.; Oldham, M. C.

10.1101/265397 — neuroscience — Posted on 2018-02-14

973 Frequency selective encoding of substrate vibrations in the somatosensory cortex

Prsa, M.; Huber, D.

10.1101/264747 — neuroscience — Posted on 2018-02-14

974 The DNA repair associated protein Gadd45g regulates the temporal coding of immediate early gene expression and is required for the consolidation of associative fear memory

Li, X.; Marshall, P.; Leighton, L.; Zajackowski, E.; Bredy, T.; Wei, W.

10.1101/265355 — neuroscience — Posted on 2018-02-14

975 Dissociating decision confidence from evidence reliability in the human brain

Bang, D.; Fleming, S. M.

10.1101/251330 — neuroscience — Posted on 2018-02-14

976 An Augmented Aging Process in Brain White Matter in HIV

Kuhn, T.; Kaufmann, T.; Doan, N. T.; Westlye, L. T.; Jones, J. D.; Nunez, R. A.; Bookheimer, S. Y.; Singer, E. J.; Hinkin, C. H.; Thames, A. D.

10.1101/265199 — neuroscience — Posted on 2018-02-14

977 Occipitotemporal Representations Reflect Individual Differences in Conceptual Knowledge

Braunlich, K.; Love, B. C.

10.1101/264895 — neuroscience — Posted on 2018-02-14

978 RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection

Ates, L. S.; Sayes, F.; Frigui, W.; Ummels, R.; Damen, M. P. M.; Bottai, D.; Behr, M. A.; Bitter, W.; Majlessi, L.; Brosch, R.

10.1101/265462 — microbiology — Posted on 2018-02-14

979 The intestinal microbiota predisposes to traveller’s diarrhoea and to the carriage of multidrug-resistant Enterobacteriaceae after travelling to tropical regions

Leo, S.; Lazarevic, V.; Gaia, N.; Estellat, C.; Girard, M.; Matheron, S.; Armand-Lefevre, L.; Andremont, A.; The VOYAG-R Study Group, ; Schrenzel, J.; Ruppe, E.

10.1101/265033 — microbiology — Posted on 2018-02-14

980 Persistent Chikungunya Virus Replication in Human Cells is Associated with Presence of Stable Cytoplasmic Granules Containing Non-structural Protein 3

Remenyi, R.; Gao, Y.; Hughes, R. E.; Curd, A.; Zothner, C.; Peckham, M.; Merits, A.; Harris, M.

10.1101/236703 — microbiology — Posted on 2018-02-14

981 Protein Kinase A Negatively Regulates Ca2+ signalling in Toxoplasma gondii

Uboldi, A. D.; Wilde, M.-L.; McRae, E. A.; Stewart, R. J.; Dagley, L. F.; Yang, L.; Katris, N. J.; Hapuarachchi, S. V.; Coffey, M. J.; Lehane, A. M.; Botte, C. Y.; Waller, R. F.; Webb, A. I.; Tonkin, C. J.

10.1101/265371 — microbiology — Posted on 2018-02-14

982 Competence Inhibition by the XrpA Peptide Encoded Within the comX Gene of Streptococcus mutans

Kaspar, J.; Shields, R.; Burne, R.

10.1101/265223 — microbiology — Posted on 2018-02-14

983 Cyfip1 haploinsufficiency increases compulsive-like behavior and paternally inherited palatable food intake: Implications for Prader-Willi Syndrome

Babbs, R. K.; Ruan, Q. T.; Kelliher, J. C.; Feng, A. X.; Kirkpatrick, S. L.; Benitez, F. A.; Rodriguez, F. A.; Pierre, J.; Kumar, V.; Mulligan, M. K.; Bryant, C. D.

10.1101/264846 — genetics — Posted on 2018-02-14

984 The expansion of apolipoprotein D genes in cluster in teleost fishes

Gu, L.; Xia, C.

10.1101/265538 — evolutionary biology — Posted on 2018-02-14

985 Convergence in form and function overcomes non-parallel evolutionary histories in Arctic charr

Jacobs, A.; Carruthers, M.; Yurchenko, A.; Gordeeva, N.; Alekseyev, S.; Hooker, O.; Leong, J.; Rondeau, E.; Koop, B.; Adams, C.; Elmer, K. R.

10.1101/265272 — evolutionary biology — Posted on 2018-02-14

986 Tradeoffs and cultural diversity

Karin, O.; Alon, U.

10.1101/263905 — evolutionary biology — Posted on 2018-02-14

987 Evolution of male costs of copulation in sepsid flies (Diptera: Sepsidae)

Rohner, P. T.; Shen Yoong, K.; Tuan, M. J. M.; Meier, R.

10.1101/265439 — evolutionary biology — Posted on 2018-02-14

988 Size-dependent movement explains why bigger is better in fragmented landscapes

Hillaert, J.; Hovestadt, T.; Vandegehuchte, M. L.; Bonte, D.

10.1101/264861 — ecology — Posted on 2018-02-14

989 Information use during movement regulates how fragmentation and loss of habitat affect body size.

Hillaert, J.; Vandegehuchte, M. L.; Hovestadt, T.; Bonte, D.

10.1101/265025 — ecology — Posted on 2018-02-14

990 Homogenization of species composition and species association networks are decoupled

Li, D.; Poisot, T.; Waller, D.; Baiser, B.

10.1101/265264 — ecology — Posted on 2018-02-14

991 The transcription factor Tfap2e/AP-2ε plays a pivotal role in maintaining the identity of basal vomeronasal sensory neurons

Lin, J. M.; Taroc, E. Z. M.; Frias, J. A.; Prasad, A.; Catizone, A. N.; Sammons, M. A.; Forni, P. E.

10.1101/265280 — developmental biology — Posted on 2018-02-14

992 A Highly Efficient and Faithful MDS Patient-Derived Xenotransplantation Model for Pre-Clinical Studies

Song, Y.; Rongvaux, A.; Taylor, A.; Jiang, T.; Tebaldi, T.; Balasubramanian, K.; Bagale, A.; Terzi, Y. K.; Gbyli, R.; Wang, X.; Zhao, J.; Podoltsev, N.; Xu, M.; Neparidze, N.; Wong, E.; Torres, R.; Bruscia, E. M.; Kluger, Y.; Manz, M. G.; Flavell, R. A.; Halene, S.

10.1101/265082 — cancer biology — Posted on 2018-02-14

993 SV-plaudit: A cloud-based framework for manually curating thousands of structural variants

Belyeu, J. R.; Nicholas, T. J.; Pedersen, B. S.; Sasani, T. A.; Havrilla, J. M.; Kravitz, S. N.; Conway, M. E.; Lohman, B. K.; Quinlan, A. R.; Layer, R. M.

10.1101/265058 — bioinformatics — Posted on 2018-02-14

994 End-to-end differentiable learning of protein structure

AlQuraishi, M.

10.1101/265231 — bioinformatics — Posted on 2018-02-14

995 Moonlight: a tool for biological interpretation and driver genes discovery

Colaprico, A.; Olsen, C.; Cava, C.; Terkelsen, T.; Silva, T. C.; Olsen, A.; Cantini, L.; Bertoli, G.; Zinovyev, A.; Barillot, E.; Castiglioni, I.; Noushmehr, H.; Papaleo, E.; Bontempi, G.

10.1101/265322 — bioinformatics — Posted on 2018-02-14

996 Modelling cell-cell interactions from spatial molecular data with spatial variance component analysis

Arnol, D.; Schapiro, D.; Bodenmiller, B.; Saez-Rodriguez, J.; Stegle, O.

10.1101/265256 — bioinformatics — Posted on 2018-02-14

997 Quantifying Expansion Microscopy with DNA Origami Expansion Nanorulers

Scheible, M. B.; Tinnefeld, P.

10.1101/265405 — biochemistry — Posted on 2018-02-14

998 Uncertainty and exploration

Gershman, S. J.

10.1101/265504 — animal behavior and cognition — Posted on 2018-02-14

999 Identifying tissues implicated in Anorexia Nervosa using Transcriptomic Imputation

Huckins, L. M.; Dobbyn, A.; McFadden, W.; Ruderfer, D.; Wang, W.; Gamazon, E. R.; Leppa, V.; Eating Disorders working group of the Psychiatric Genomics Consortium (PGC-ED), ; Devlin, B.; Sieberts, S. K.; Cox, N.; Im, H. K.; Breen, G.; Sklar, P.; Bulik, C.; Stahl, E. A.

10.1101/265017 — genetics — Posted on 2018-02-14

1000 Metabarcoding lake sediments: taphonomy and representation of contemporary vegetation in environmental DNA (eDNA) records

Alsos, I. G.; Lammers, Y.; Yoccoz, N. G.; Joergensen, T.; Sjoegren, P.; Gielly, L.; Edwards, M. E.

10.1101/264903 — ecology — Posted on 2018-02-14

1001 From the cage to the wild: Introductions of Psittaciformes to Puerto Rico with emphasis on the invasive ecology of the white-winged parakeet

Falcon, W.; Tremblay, R. L.

10.1101/264937 — ecology — Posted on 2018-02-14

1002 Edge fires drive the shape and stability of tropical forests

Hebert-Dufresne, L.; Pellegrini, A.; Bhat, U.; Redner, S.; Pacala, S.; Berdahl, A.

10.1101/265124 — ecology — Posted on 2018-02-14

1003 Exploring the relationship between altmetrics and traditional measures of dissemination in health professions education

Maggio, L. A.; Leroux, T.; Meyer, H. S.; Artino, A. R.

10.1101/260059 — scientific communication and education — Posted on 2018-02-13

1004 Transcriptional Activation of a Cartilaginous Fish (Elephant Shark, Callorhinchus milii) Mineralocorticoid Receptor by Corticosteroids, Progestins and Spironolactone

Katsu, Y.; Kohno, S.; Oka, K.; Lin, X.; Otake, S.; Pillai, N. E.; Takagi, W.; Hyodo, S.; Venkatesh, B.; Baker, M. E.

10.1101/265348 — physiology — Posted on 2018-02-13

1005 Multiplex single-molecule DNA barcoding using an oligonucleotide ligation assay

Severins, I.; Szczepaniak, M.; Joo, C.

10.1101/265215 — biophysics — Posted on 2018-02-13

1006 Combinatorial library of biodegradable polyesters enables delivery of plasmid DNA to polarized human RPE monolayers for retinal gene therapy

Mishra, B.; Wilson, D. R.; Sripathi, S. R.; Suprenant, M. P.; Rui, Y.; Wahlin, K. J.; Berlinicke, C.; Green, J. J.; Zack, D. J.

10.1101/264390 — bioengineering — Posted on 2018-02-13

1007 Empirical Bayes Meets Information Theoretical Network Reconstruction from Single Cell Data

Chan, T. E.; Pallaseni, A.; Babtie, A. C.; McEwen, K.; Stumpf, M. P. H.

10.1101/264853 — systems biology — Posted on 2018-02-13

1008 Resting heart rate and psychopathy: Findings from the Add Health Survey

Kavish, N. A.; Fu, Q.; Vaughn, M.; Qian, Z.; Boutwell, B.

10.1101/205005 — physiology — Posted on 2018-02-13

1009 F-actin patches nucleated on chromosomes coordinate capture by microtubules in oocyte meiosis

Burdyniuk, M.; Callegari, A.; Mori, M.; Nedelec, F.; Lenart, P.

10.1101/265009 — cell biology — Posted on 2018-02-13

1010 In silico mechanobiochemical modeling of morphogenesis in cell monolayers

Marzban, B.; Ma, X.; Qing, X.; Yuan, H.

10.1101/189175 — biophysics — Posted on 2018-02-13

1011 Machine learning methods to reverse engineer dynamic gene regulatory networks governing cell state transitions

Tsakanikas, P.; Manatakis, D. V.; Manolakos, E. S.

10.1101/264671 — bioinformatics — Posted on 2018-02-13

1012 An integrated approach to comprehensively map the molecular context of proteins

Liu, X.; Salokas, K.; Tamene, F.; Varjosalo, M.

10.1101/264788 — systems biology — Posted on 2018-02-13

1013 The impact on authors and editors of introducing Data Availability Statements at Nature journals

Grant, R.; Hrynaszkiewicz, I.

10.1101/264929 — scientific communication and education — Posted on 2018-02-13

1014 Water availability dynamics have long-term effects on mature stem structure in Vitis vinifera

Munitz, S.; Netzer, Y.; Shtein, I.; Schwartz, A.

10.1101/265207 — plant biology — Posted on 2018-02-13

1015 Functional determinants of enhanced and depressed inter-areal information flow in NREM sleep between neuronal ensembles in rat cortex and hippocampus

Olcese, U.; Bos, J. J.; Vinck, M.; Pennartz, C. M. A.

10.1101/264820 — neuroscience — Posted on 2018-02-13

1016 Layer-specific integration of locomotion and concurrent wall touching in mouse barrel cortex

Ayaz, A.; Staeuble, A.; Saleem, A. B.; Helmchen, F.

10.1101/265165 — neuroscience — Posted on 2018-02-13

1017 Mef-2 and p300 interact to regulate expression of the homeostatic regulator Pumilio in Drosophila

Lin, W.-H.; Baines, R.

10.1101/264911 — neuroscience — Posted on 2018-02-13

1018 The histone chaperones FACT and ANP32E reshape the chromatin landscape during DNA damage repair through H2A.Z/H2A.X histone variant exchange

Piquet, S.; Le Parc, F.; Bai, S.-K.; Chevallier, O.; Adam, S.; Polo, S. E.

10.1101/264952 — molecular biology — Posted on 2018-02-13

1019 Influenza A viruses use multivalent sialic acid clusters for cell binding and receptor activation

Sieben, C.; Sezgin, E.; Eggeling, C.; Manley, S.

10.1101/264713 — microbiology — Posted on 2018-02-13

1020 Axenic Aedes aegypti develop without live bacteria, but exhibit delayed development and reduced oviposition.

Correa, M. A.; Brackney, D. E.; Steven, B.

10.1101/264978 — microbiology — Posted on 2018-02-13

1021 Transgenerational inheritance of shuffled symbiont communities in the coral Montipora digitata

Quigley, K.; Willis, B.; Kenkel, C.

10.1101/264796 — microbiology — Posted on 2018-02-13

1022 A long-chain fatty acid elongase Elovl6 regulates mechanical damage-induced keratinocyte death and skin inflammation

Shibuya, A.; Nakamura, Y.; Matsuzaka, T.; Tahara-Hanaoka, S.; Shibuya, K.; Shimano, H.; Nakahashi-Oda, C.

10.1101/264838 — immunology — Posted on 2018-02-13

1023 Neo-formation of chromosomes in bacteria

Poirion, O. B.; Lafay, B.

10.1101/264945 — genomics — Posted on 2018-02-13

1024 Reverse transcriptase fused CRISPR-Cas1 locus with RNA-seq expression necessitates revisiting hypothesis on acquisition of antibiotic resistance genes in multidrug-resistant Enterococcus faecalis V583

Chakraborty, S.

10.1101/263558 — genomics — Posted on 2018-02-13

1025 MethCP: Differentially Methylated Region Detection with Change Point Models

Gong, B.; Purdom, E.

10.1101/265116 — genomics — Posted on 2018-02-13

1026 Saccharomyces cerevisiae histone Chaperones FACT and Spt6 modulate Pol II and histone occupancy genome-wide

Pathak, R.; Singh, P.; Ananthakrishnan, S.; Adamczyk, S.; Schimmel, O.; Govind, C. K.

10.1101/265074 — genetics — Posted on 2018-02-13

1027 Plant quarantine alarm: as much as 20 new alien insect pest species including Drosophila suzukii appeared in the Caucasus in the last seven years

Orlova-Bienkowskaja, M. J.; Bienkowski, A. O.; Karpun, N. N.

10.1101/264127 — ecology — Posted on 2018-02-13

1028 A plant biodiversity effect resolved to a single locus

Wuest, S. E.; Niklaus, P. A.

10.1101/264960 — ecology — Posted on 2018-02-13

1029 Dispersal limitation and thermodynamic constraints govern spatial structure of permafrost microbial communities

Bottos, E. M.; Kennedy, D. W.; Romero, E. B.; Fansler, S. J.; Brown, J. M.; Bramer, L. M.; Chu, R. K.; Tfaily, M. M.; Jansson, J. K.; Stegen, J. C.

10.1101/265132 — ecology — Posted on 2018-02-13

1030 The C. elegans heterochronic gene lin-28 coordinates the timing of hypodermal and somatic gonadal programs for hermaphrodite reproductive system morphogenesis

Choi, S.; Ambros, V.

10.1101/265314 — developmental biology — Posted on 2018-02-13

1031 The Atypical Rho GTPase CHW-1 Works With SAX-3/Robo to Mediate Axon Guidance in Caenorhabditis elegans

Alan, J.; Robinson, S.; Magsig, K.; Demarco, R.; Lundquist, E. A.

10.1101/265066 — developmental biology — Posted on 2018-02-13

1032 Morphometric analysis of spread platelets identifies integrin αIIbβ3-specific contractile phenotype

Lickert, S.; Sorrentino, S.; Studt, J.-D.; Medalia, O.; Vogel, V.; Schoen, I.

10.1101/264804 — cell biology — Posted on 2018-02-13

1033 Markov chain models of cancer metastasis

Mason, J.; Newton, P. K.

10.1101/263350 — cancer biology — Posted on 2018-02-13

1034 CRISPR Cas9 searches for a protospacer adjacent motif by one-dimensional diffusion

Globyte, V.; Lee, S. H.; Bae, T.; Kim, J.-S.; Joo, C.

10.1101/264879 — biophysics — Posted on 2018-02-13

1035 Motif Scraper: A cross-platform, open-source tool for identifying degenerate nucleotide motif matches in FASTA files

Roberson, E. D. O.

10.1101/265108 — bioinformatics — Posted on 2018-02-13

1036 Machine learning of stem cell identities from single-cell expression data via regulatory network archetypes

Stumpf, P. S.; MacArthur, B. D.

10.1101/208470 — systems biology — Posted on 2018-02-13

1037 Mathematical modelling of cortical neurogenesis reveals that the founder population does not necessarily scale with neuronal output

Picco, N.; Garcia-Moreno, F.; Woolley, T.; Maini, P.; Molnar, Z.

10.1101/206045 — neuroscience — Posted on 2018-02-13

1038 A Bayesian Framework for Multiple Trait Colocalization from Summary Association Statistics

Giambartolomei, C.; Zhenli Liu, J.; Zhang, W.; Hauberg, M.; Shi, H.; Boocock, J.; Pickrell, J.; Jaffe, A. E.; CommonMind Consortium, ; Pasaniuc, B.; Roussos, P.

10.1101/155481 — genomics — Posted on 2018-02-13

1039 AnoniMME: Bringing Anonymity to the Matchmaker Exchange Platform for Rare Disease Gene Discovery

Oprisanu, B.; De Cristofaro, E.

10.1101/262295 — genomics — Posted on 2018-02-13

1040 What is an archaeon and are the Archaea really unique?

Harish, A.

10.1101/256263 — evolutionary biology — Posted on 2018-02-13

1041 PANOPLY: Omics-guided drug prioritization method tailored to an individual patient

Kalari, K. R.; Sinnwell, J. P.; Thompson, K. J.; Tang, X.; Carlson, E. E.; Yu, J.; Vedell, P. T.; Ingle, J. N.; Weinshilboum, R.; Wang, L.; Boughey, J. C.; Goetz, M. P.; Suman, V. J.

10.1101/176396 — bioinformatics — Posted on 2018-02-13

1042 Guidance on filtering DNA methylation microarray probes by detection p-values

Heiss, J. A.; Just, A. C.

10.1101/245217 — bioinformatics — Posted on 2018-02-13

1043 Metabolomics profile of umbilical cord blood is associated with maternal pre-pregnant obesity in a prospective multi-ethnic cohort displaying health disparities

Alakwaa, F.; Schlueter, R.; Benny, P.; Gurary, A.; Xie, G.; Jia, W.; Chun, S.; Chern, I.; Garmire, L.

10.1101/264374 — bioinformatics — Posted on 2018-02-13

1044 Actin and Src-family kinases regulate nuclear YAP1 and its export

Ege, N.; Dowbaj, A. M.; Jiang, M.; Howell, M.; Jenkins, R. P.; Sahai, E.

10.1101/201004 — molecular biology — Posted on 2018-02-13

1045 A cancer pharmacogenomic screen powering crowd-sourced advancement of drug combination prediction

Menden, M. P.; Wang, D.; Guan, Y.; Mason, M.; Szalai, B.; Bulusu, K. C.; Yu, T.; Kang, J.; Jeon, M.; Wolfinger, R.; Nguyen, T.; Zaslavskiy, M.; AstraZeneca-Sanger Drug Combination DREAM Consorti, ; Jang, I. S.; Ghazoui, Z.; Ahsen, M. E.; Vogel, R.; Chaibub Neto, E.; Norman, T.; Tang, E. K.; Garnett, M. J.; Di Veroli, G.; Fawell, S.; Stolovitzky, G.; Guinney, J.; Dry, J. R.; Saez-Rodriguez, J.

10.1101/200451 — bioinformatics — Posted on 2018-02-13

1046 Inferotemporal cortex reflects behaviorally-relevant target match information during invariant object search

Roth, N.; Rust, N. C.

10.1101/152181 — neuroscience — Posted on 2018-02-13

1047 Single-exposure visual memory judgments are reflected in IT cortex

Meyer, T.; Rust, N. C.

10.1101/197764 — neuroscience — Posted on 2018-02-13

1048 AnoniMME: Bringing Anonymity to the Matchmaker Exchange Platform for Rare Disease Gene Discovery

Oprisanu, B.; De Cristofaro, E.

10.1101/262295 — genomics — Posted on 2018-02-13

1049 Genome-wide enhancer - gene regulatory maps in two vertebrate genomes

Clement, Y.; Torbey, P.; Gilardi-Hebenstreit, P.; Roest Crollius, H.

10.1101/244475 — genomics — Posted on 2018-02-13

1050 mRNA expression-mediated gene repression in human cells

Hollerer, I.; Barker, J. C.; Jorgensen, V.; Tresenrider, A.; Dugast-Darzacq, C.; Darzacq, X.; Chan, L. Y.; Tjian, R.; Ünal, E.; Brar, G. A.

10.1101/264721 — genetics — Posted on 2018-02-13

1051 Pleistocene climate change and the formation of regional species pools

Calatayud, J.; Rodriguez, M. A.; Molina-Venegas, R.; Leo, M.; Horreo, J. L.; Hortal, J.

10.1101/149617 — ecology — Posted on 2018-02-13

1052 Clust: automatic extraction of optimal co-expressed gene clusters from gene expression data

Abu-Jamous, B.; Kelly, S.

10.1101/221309 — bioinformatics — Posted on 2018-02-13

1053 Structure of a novel dimeric SET domain methyltransferase that regulates cell motility

Pivovarova, Y.; Liu, J.; Lesigang, J.; Koldyka, O.; Rauschmeier, R.; Hu, K.; Dong, G.

10.1101/264291 — biochemistry — Posted on 2018-02-13

1054 Cross-modal and non-monotonic representations of statistical regularity are encoded in local neural response patterns

Nastase, S. A.; Davis, B.; Hasson, U.

10.1101/243550 — neuroscience — Posted on 2018-02-13

1055 An atlas of genetic variation for linking pathogen-induced cellular traits to human disease

Wang, L.; Pittman, K. J.; Barker, J. R.; Salinas, R. E.; Stanaway, I. B.; Williams, G. D.; Carroll, R. J.; Balmat, T.; Ingham, A.; Gopalakrishnan, A. M.; Gibbs, K. D.; Antonia, A. L.; The eMERGE Network, ; Heitman, J.; Lee, S. C.; Jarvick, G. P.; Denny, J. C.; Horner, S. M.; Delong, M. R.; Valdivia, R. H.; Crosslin, D. R.; Ko, D. C.

10.1101/202325 — genetics — Posted on 2018-02-13

1056 Extended logistic growth model for heterogeneous populations

Jin, W.; McCue, S.; Simpson, M.

10.1101/231100 — cell biology — Posted on 2018-02-13

1057 Stress matters: a double-blind, randomized controlled trial on the effects of a multispecies probiotic on neurocognition

Papalini, S.; Michels, F.; Kohn, N.; Wegman, J.; van Hemert, S.; Roelofs, K.; Arias Vasquez, A.; Aarts, E.

10.1101/263673 — neuroscience — Posted on 2018-02-13

1058 Competition in biofilms between Pseudomonas aeruginosa cystic fibrosis isolates is driven by R-pyocins

Oluyombo, O.; Diggle, S. P.; Penfold, C. N.

10.1101/264580 — microbiology — Posted on 2018-02-13

1059 HLA-B*39:06 Efficiently Mediates Type 1 Diabetes in a Mouse Model Incorporating Reduced Thymic Insulin Expression

Schloss, J.; Ali, R.; Racine, J. J.; Chapman, H.; Serreze, D.; DiLorenzo, T.

10.1101/264531 — immunology — Posted on 2018-02-13

1060 Axon Guidance Signaling Modulates Epithelial to Mesenchymal Transition in Stem Cell-Derived Retinal Pigment Epithelium

Sripathi, S. R.; Liu, M. M.; Hu, M.-W.; Wan, J.; Cheng, J.; Duan, Y.; Mertz, J.; Wahlin, K.; Maruotti, J.; Berlinicke, C. A.; Qian, J.; Zack, D. J.

10.1101/264705 — genomics — Posted on 2018-02-13

1061 A widespread decrease of chromatin accessibility in age-related macular degeneration

Wang, J.; Zibetti, C.; Shang, P.; Sripathi, S. R.; Zhang, P.; Cano, M.; Hoang, T.; Ji, H.; Merbs, S. L.; Zack, D. J.; Handa, J. T.; Sinha, D.; Blackshaw, S.; Qian, J.; Xia, S.

10.1101/264564 — genomics — Posted on 2018-02-13

1062 Segmenting accelerometer data from daily life with unsupervised machine learning

van Kuppevelt, D. E.; Heywood, J.; Hamer, M.; Sabia, S.; Fitzsimons, E.; van Hees, V.

10.1101/263046 — epidemiology — Posted on 2018-02-13

1063 Modeling Uncertainty in Grapevine Powdery Mildew Epidemiology Using Fuzzy Logic

Choudhury, R. A.; Mahaffee, W.; McRoberts, N.; Gubler, W. D.

10.1101/264622 — epidemiology — Posted on 2018-02-13

1064 Considerations for the design of vaccine efficacy trials during public health emergencies

Dean, N. E.; Gsell, P.-S.; Brookmeyer, R.; DeGruttola, V.; Donnelly, C.; Halloran, M. E.; Jasseh, M.; Nason, M. C.; Riveros Balta, A. X.; Watson, C.; Henao-Restrepo, A. M.; Longini, I. M.

10.1101/261875 — epidemiology — Posted on 2018-02-13

1065 Real-time fine aerosol exposures in taconite mining operations

Huynh, T.; Ramachandran, G.; Quick, H.; Hwang, J.; Raynor, P. C.; Alexander, B. H.; Mandel, J. H.

10.1101/263442 — epidemiology — Posted on 2018-02-13

1066 Competition and immigration lead to clusters of similar species, not trait separation

D'Andrea Rocha, R.; Riolo, M.; Ostling, A. M.

10.1101/264606 — ecology — Posted on 2018-02-13

1067 Cardiovascular Disease Risk Factor Responses to a Type 2 Diabetes Care Model Including Nutritional Ketosis at One Year: An Open Label, Non-Randomized, Controlled Study

Bhanpuri, N. H.; Hallberg, S. J.; Williams, P. T.; MnKenzie, A. L.; Ballard, K. D.; Campbell, W. W.; McCarter, J. P.; Phinney, S. D.; Volek, J. S.

10.1101/262709 — clinical trials — Posted on 2018-02-13

1068 Characterizing the 3D structure and dynamics of chromosomes and proteins in a common contact matrix framework

Lindsay, R. J.; Pham, B.; Shen, T.; McCord, R. P.

10.1101/264515 — biophysics — Posted on 2018-02-13

1069 A Convenient Non-harm Cervical Spondylosis Intelligent Identity method based on Machine Learning

Wang, N.; Huang, Y.; Cui, L.; Fan, F.; Huang, X.; Rao, Y.; Xiao, J.; Lu, J.

10.1101/264663 — bioinformatics — Posted on 2018-02-13

1070 MasterPATH: network analysis of functional genomics screening data

Rubanova, N.; Polesskaya, A.; Campalans, A.; Pinna, G.; Kropp, J.; Harel-Bellan, A.; Morozova, N.

10.1101/264119 — systems biology — Posted on 2018-02-13

1071 FGF21, a liver hormone that inhibits alcohol intake in mice, increases in human circulation after acute alcohol ingestion and sustained binge drinking at Oktoberfest

Soeberg, S.; Andersen, E. S.; Dalgaard, N. B.; Jarlhelt, I.; Hansen, N. L.; Hoffmann, N.; Vilsboell, T.; Chenchar, A.; Jensen, M.; Grevengoed, T. J.; Trammell, S. A. J.; Knop, F. K.; Gillum, M. P.

10.1101/264234 — physiology — Posted on 2018-02-13

1072 Targeting redox regulatory site of protein kinase B impedes neutrophilic inflammation

Hwang, T.-L.; Chen, P.-J.; Ko, I.-L.; Lee, C.-L.; Hu, H.-C.; Chang, F.-R.; Wu, Y.-C.; Leu, Y.-L.; Wu, C.-C.; Tsai, Y.-F.; Lin, C.-Y.; Pan, C.-Y.

10.1101/264184 — pharmacology and toxicology — Posted on 2018-02-13

1073 Lower performance of Toxoplasma-infected, Rh-negative subjects in the weight holding and hand-grip tests

Flegr, J.; Sebankova, B.; Priplatova, L.; Chvatalova, V.; Kankova, S.

10.1101/264093 — pathology — Posted on 2018-02-13

1074 A Hierarchical Anti-Hebbian Network Model for the Formation of Spatial Cells in Three-Dimensional Space

Soman, K.; Chakravarthy, S.; Yartsev, M.

10.1101/264366 — neuroscience — Posted on 2018-02-13

1075 Representation of multiple objects in macaque category-selective areas

Bao, P.; Tsao, D. Y.

10.1101/264465 — neuroscience — Posted on 2018-02-13

1076 Multisensory perception reflects individual differences in processing temporal correlations

Nidiffer, A.; Diederich, A.; Ramachandran, R.; Wallace, M. T.

10.1101/264457 — neuroscience — Posted on 2018-02-13

1077 Maturation Trajectories of Cortical Resting-State Networks Depend on the Mediating Frequency Band

Khan, S.; Hashmi, J.; Mamashli, F.; Michmizos, K.; Kitzbichler, M.; Bharadwaj, H.; Bekhti, Y.; Ganesan, S.; Garel, K. A.; Whitfield-Gabrieli, S.; Gollub, R.; Kong, J.; Vaina, L. M.; Rana, K.; Stufflebeam, S.; Hamalainen, M.; Kenet, T.

10.1101/264416 — neuroscience — Posted on 2018-02-13

1078 A Novel QconCAT-Based Proteomics Method for Determining Allele-Specific Protein Expression (ASPE): a New Approach to Identify Cis-acting Genetic Variants

Shi, J.; Wang, X.; Zhu, H.; Jiang, H.; Wang, D.; Zhu, H.-J.

10.1101/264614 — molecular biology — Posted on 2018-02-13

1079 Two novel strains of Torulaspora delbrueckii isolated from the honey bee gut microbiome and their use in honey fermentation

Barry, J. P.; Metz, M. S.; Hughey, J.; Quirk, A.; Bochman, M.

10.1101/264317 — microbiology — Posted on 2018-02-13

1080 The Spectre of Too Many Species

Leache, A.; Zhu, T.; Rannala, B.; Yang, Z.

10.1101/263996 — evolutionary biology — Posted on 2018-02-13

1081 Reducing compositional fluctuations facilitates artificial selection of microbial community function

Xie, L.; Shou, W.

10.1101/264689 — evolutionary biology — Posted on 2018-02-13

1082 Targeted mutation detection in breast cancer using MammaSeqTM

Smith, N. G.; Gyanchandani, R.; Gurda, G. T.; Lucas, P. C.; Hartmaier, R.; Brufsky, A. M.; Puhalla, S.; Bahreini, A.; Kota, K.; Wald, A.; Nikiforov, Y. E.; Nikiforova, M. N.; Oesterrich, S.; Lee, A. V.

10.1101/264267 — cancer biology — Posted on 2018-02-13

1083 Metabolomics profile of umbilical cord blood is associated with maternal pre-pregnant obesity in a prospective multi-ethnic cohort displaying health disparities

Alakwaa, F.; Schlueter, R.; Garmire, L.; Benny, P.; Gurary, A.; Xie, G.; Jia, W.; Chun, S.; Chern, I.

10.1101/264374 — bioinformatics — Posted on 2018-02-13

1084 Enhancer Identification using Transfer and Adversarial Deep Learning of DNA Sequences

Cohn, D.; Zuk, O.; Kaplan, T.

10.1101/264200 — bioinformatics — Posted on 2018-02-13

1085 Information synergy: adding unambiguous quality information rescues social information use in ants

Czaczkes, T. J.; Beckwith, J. J.

10.1101/219980 — animal behavior and cognition — Posted on 2018-02-13

1086 Genotyping-by-sequencing supports a genetic basis for alpine wing-reduction in a New Zealand stonefly

Veale, A. J.; Foster, B. J.; Dearden, P. K.; Waters, J. M.

10.1101/264473 — evolutionary biology — Posted on 2018-02-13

1087 Community function landscape and steady state species composition shape the eco-evolutionary dynamics of arti1cial community selection

Xie, L.; Shou, W.

10.1101/264697 — evolutionary biology — Posted on 2018-02-13

1088 Developmental Mechanisms Linking Form and Function During Jaw Evolution

Woronowicz, K. C.; Gline, S. E.; Herfat, S. T.; Fields, A. J.; Schneider, R. A.

10.1101/264556 — developmental biology — Posted on 2018-02-13

1089 The universally-conserved transcription factor RfaH is recruited to a hairpin structure of the non-template DNA strand

Zuber, P. K.; Schweimer, K.; NandyMazumdar, M.; Liu, Z.; Nedialkov, Y.; Artsimovitch, I.; Roesch, P.; Knauer, S. H.

10.1101/264887 — biochemistry — Posted on 2018-02-13

1090 Hawkmoth flight in the unsteady wakes of flowers

Matthews, M.; Sponberg, S.

10.1101/264762 — animal behavior and cognition — Posted on 2018-02-13

1091 Continuous flash suppression and monocular pattern masking impact subjective awareness similarly

Knotts, J. D.; Lau, H.; Peters, M. A. K.

10.1101/264598 — animal behavior and cognition — Posted on 2018-02-13

1092 Two levels of host-specificity in a fig-associated Caenorhabditis

Woodruff, G. C.; Phillips, P. C.

10.1101/261958 — ecology — Posted on 2018-02-13

1093 Heterochromatin and the Synaptonemal Complex Maintain Homologous Centromere Interactions in Mouse Spermatocytes

Guiraldelli, M. F.; Eyster, C.; Lee, C.-Y.; Dawson, D. S.; Pezza, R. J.

10.1101/264432 — cell biology — Posted on 2018-02-12

1094 Tunable molecular tension sensors reveal extension-based control of vinculin loading

LaCroix, A. S.; Lynch, A. D.; Berginski, M. E.; Hoffman, B. D.

10.1101/264549 — biophysics — Posted on 2018-02-12

1095 Centrality and the shortest path approach on the human interactome

Rubanova, N.; Morozova, N.

10.1101/264069 — systems biology — Posted on 2018-02-12

1096 -Florbetapir PET: Towards Predicting Dementia in Adults with Down Syndrome

Keator, D. B.; Doran, E.; VanErp, T. G. M.; Phelan, M. J.; Tseung, K.; Yassa, M. A.; Potkin, S. G.; Lott, I. T.

10.1101/235440 — neuroscience — Posted on 2018-02-12

1097 Redundancy makes music and speech robust to individual differences in perception

Jasmin, K.; Dick, F.; Tierney, A. T.

10.1101/263079 — neuroscience — Posted on 2018-02-12

1098 Control of Spreading Depression with Electrical Fields

Whalen, A. J.; Xiao, Y.; Kadji, H.; Dahlem, M.; Gluckman, B. J.; Schiff, S. J.

10.1101/234005 — neuroscience — Posted on 2018-02-12

1099 Altered cingulate and substantia nigra/ventral tegmental activation to novelty and emotional salience in antipsychotic naive first episode psychosis patients

Knolle, F.; Ermakova, A. O.; Justicia, A.; Fletcher, P. C.; Bunzeck, N.; Duzel, E.; Murray, G.

10.1101/263020 — neuroscience — Posted on 2018-02-12

1100 Multiple laboratory mouse reference genomes define strain specific haplotypes and novel functional loci

Lilue, J.; Doran, A. G.; Fiddes, I. T.; Abrudan, M.; Armstrong, J.; Bennett, R.; Chow, W.; Collins, J.; Czechanski, A.; Danecek, P.; Diekhans, M.; Dolle, D.-D.; Dunn, M.; Durbin, R.; Earl, D.; Ferguson-Smith, A.; Flicek, P.; Flint, J.; Frankish, A.; Fu, B.; Gerstein, M.; Gilbert, J.; Goodstadt, L.; Harrow, J.; Howe, K.; Kolmogorov, M.; Koenig, S.; Lelliott, C.; Loveland, J.; Mott, R.; Muir, P.; Navarro, F.; Odom, D.; Park, N.; Pelan, S.; Phan, S. K.; Quail, M.; Reinholdt, L.; Romoth, L.; Shirley, L.; Sisu, C.; Sjoberg-Herrera, M.; Stanke, M.; Steward, C.; Thomas, M.; Threadgold, G.; Thybert, D

10.1101/235838 — genomics — Posted on 2018-02-12

1101 Copy number variants in clinical WGS: deployment and interpretation for rare and undiagnosed disease

Gross, A.; Ajay, S. S.; Rajan, V.; Brown, C.; Bluske, K.; Burns, N.; Chawla, A.; Coffey, A. J.; Malhotra, A.; Scocchia, A.; Thorpe, E.; Dzidic, N.; Hovanes, K.; Sahoo, T.; Dolzhenko, E.; Lajoie, B.; Khouzam, A.; Chowdhury, S.; Belmont, J.; Roller, E.; Ivakhno, S.; Tanner, S.; McEachern, J.; Hambuch, T.; Eberle, M.; Hagelstrom, R. T.; Bentley, D. R.; Perry, D. L.; Taft, R. J.

10.1101/245100 — genomics — Posted on 2018-02-12

1102 Long term context dependent genetic adaptation of the viral genetic cloud

Klein, T.; Borderia, A. V.; Barbezange, C.; Vignuzzi, M.; Louzoun, Y.

10.1101/262345 — genetics — Posted on 2018-02-12

1103 Mechanism of evolution by genetic assimilation: Equivalence and independence of genetic mutation and epigenetic modulation in phenotypic expression

Nishikawa, K.; Kinjo, A. R.

10.1101/242206 — evolutionary biology — Posted on 2018-02-12

1104 LinearFold: Linear-Time Prediction of RNA Secondary Structures

Deng, D.; Zhao, K.; Hendrix, D.; Mathews, D.; Huang, L.

10.1101/263509 — bioinformatics — Posted on 2018-02-12

1105 Transfer learning for biomedical named entity recognition with neural networks.

Giorgi, J. M.; Bader, G.

10.1101/262790 — bioinformatics — Posted on 2018-02-12

1106 Kmer-db: instant evolutionary distance estimation

Deorowicz, S.; Gudys, A.; Dlugosz, M.; Kokot, M.; Danek, A.

10.1101/263590 — bioinformatics — Posted on 2018-02-12

1107 Generative adversarial networks as a tool to recover structural information from cryo-electron microscopy data

Su, M.; Zhang, H.; Schawinski, K.; Zhang, C.; Cianfrocco, M. A.

10.1101/256792 — biochemistry — Posted on 2018-02-12

1108 ssRNA/DNA-Sensors via Embedded Strand-Displacement Programs in CRISPR/Cas9 Guides

Jakimo, N.; Chatterjee, P.; Jacobson, J. M.

10.1101/264424 — bioengineering — Posted on 2018-02-12

1109 Transition State Characteristics During Cell Differentiation

Brackston, R.; Lakatos, E.; Stumpf, M. P. H.

10.1101/264143 — systems biology — Posted on 2018-02-12

1110 Multivariate directed connectivity analysis (MDCA) enables decoding of directed interactions in neural and social networks

Schlegel, A.; Vance, B.; Alexander, P.; Tse, P. U.

10.1101/263665 — neuroscience — Posted on 2018-02-12

1111 Clostridium difficile alters the structure and metabolism of distinct cecal microbiomes during initial infection to promote sustained colonization

Jenior, M. L.; Leslie, J. L.; Young, V. B.; Schloss, P. D.

10.1101/211516 — microbiology — Posted on 2018-02-12

1112 Structural model of Cyc2, the primary electron acceptor of Acidithiobacillus ferrooxidans’ respiratory chain, as a modular cytochrome - β-barrel fusion protein, and mechanistic proposals based on this model

Abriata, L. A.

10.1101/262287 — biophysics — Posted on 2018-02-12

1113 Taxonomic identification from metagenomic and metabarcoding data using any genetic marker

Bengtsson-Palme, J.; Richardsson, R. T.; Meola, M.; Wurzbacher, C.; Tremblay, E. D.; Thorell, K.; Kanger, K.; Eriksson, M.; Bilodeau, G. J.; Johnson, R. M.; Hartmann, M.; Nilsson, H.

10.1101/253377 — bioinformatics — Posted on 2018-02-12

1114 Evidences of conditioned behavior in Amoeba proteus

Martinez De la Fuente, I.; Bringas, C.; Malaina, I.; Fedetz, M.; Perez-Samartin, A.; Lopez, J. I.; Perez-Yarza, G.; Boyano, M. D.

10.1101/264176 — systems biology — Posted on 2018-02-12

1115 revtools: bibliographic data visualization for evidence synthesis in R

Westgate, M. J.

10.1101/262881 — scientific communication and education — Posted on 2018-02-12

1116 Nonpolar Residues in the Presumptive Pore-Lining Helix of Mechanosensitive Channel MSL10 Influence Channel Behavior and Confirm a Non-Conducting Function

Maksaev, G.; Shoots, J.; Ohri, S.; Haswell, E.

10.1101/264283 — plant biology — Posted on 2018-02-12

1117 Brain Iron Mediates the Relationship Between Cognition and Neighborhood Socioeconomic Status in Youth

Beard, L. M.; Roalf, D. R.; Elliott, M. A.; Prabhakaran, K.; Moore, T. M.; Gur, R. E.; Satterthwaite, T. D.

10.1101/261693 — neuroscience — Posted on 2018-02-12

1118 High-Speed Imaging of Paw Withdrawal Reflex to Objectively Assess Pain State in Mice

Abdus-Saboor, I.; Fried, N. T.; Lay, M.; Dong, P.; Burdge, J.; Lu, M.; Ma, M.; Dong, X.; Long, D.; Luo, W.

10.1101/263400 — neuroscience — Posted on 2018-02-12

1119 Sequence of cognitive changes associated with development of Alzheimer’s disease in Down syndrome – data driven analysis

Firth, N. C.; Startin, C. M.; Hithersay, R.; Hamburg, S.; Wijeratne, P. A.; Mok, K. Y.; Hardy, J.; Alexander, D. C.; The LonDownS Consortium, ; Strydom, A.

10.1101/263095 — neuroscience — Posted on 2018-02-12

1120 A probabilistic model of sleep structure suggests a primary role for wake probability in overall sleep in Drosophila melanogaster

Wiggin, T. D.; Goodwin, P. R.; Donelson, N. C.; Liu, C.; Griffith, L. C.

10.1101/263301 — neuroscience — Posted on 2018-02-12

1121 Increasing the Mobility of EEG Data Collection Using a Latte Panda Computer

Kuziek, J.; Redman, E. X.; Splinter, G. D.; Mathewson, K. E.

10.1101/263376 — neuroscience — Posted on 2018-02-12

1122 Oscillations in working memory and neural binding: a mechanism for multiple memories and their interactions

Pina, J. E.; Bodner, M.; Ermentrout, B.

10.1101/263277 — neuroscience — Posted on 2018-02-12

1123 Cortical networks for encoding near and far space in the non-human primate

Clery, J.; Guipponi, O.; Odouard, S.; Wardak, C.; Ben Hamed, S.

10.1101/261677 — neuroscience — Posted on 2018-02-12

1124 Frequency and power of human alpha oscillations drift systematically and independently with time-on-task

Benwell, C. S.; London, R. E.; Tagliabue, C. F.; Veniero, D.; Gross, J.; Keitel, C.; Thut, G.

10.1101/263103 — neuroscience — Posted on 2018-02-12

1125 Temporally unconstrained decoding reveals consistent but time-varying stages of stimulus processing

Vidaurre, D.; Myers, N.; Stokes, M.; Nobre, A. C.; Woolrich, M. W.

10.1101/260943 — neuroscience — Posted on 2018-02-12

1126 Microbiota metabolic product deoxycholic acid controls chicken necrotic enteritis

Wang, H.; Latorre Cardenas, J. D.; Bansal, M.; Al-Rubaye, B.; Tellez, G.; Hargis, B.; Sun, X.

10.1101/215640 — microbiology — Posted on 2018-02-12

1127 Threshold regulation and stochasticity from the MecA/ClpCP proteolytic system in Streptococcus mutans competence

Son, M.; Kaspar, J. R.; Ahn, S.-J.; Burne, R. A.; Hagen, S. J.

10.1101/263210 — microbiology — Posted on 2018-02-12

1128 On the design of CRISPR-based single cell molecular screens

Hill, A. J.; McFaline-Figueroa, J. L.; Starita, L. M.; Gasperini, M. J.; Matreyek, K. A.; Packer, J.; Jackson, D.; Shendure, J.; Trapnell, C.

10.1101/254334 — genomics — Posted on 2018-02-12

1129 The evolution of ogres: cannibalistic growth in giant phagotrophs

Bloomfield, G.

10.1101/262378 — evolutionary biology — Posted on 2018-02-12

1130 Genetic Signatures of Lipid Metabolism Evolution in Cetacea

Endo, Y.; Kamei, K.-i.; Inoue-Murayama, M.

10.1101/250597 — evolutionary biology — Posted on 2018-02-12

1131 Variability in timing of a β-catenin pulse biases a stochastic cell fate decision in C. elegans

Kroll, J. R.; Tsiaxiras, J.; van Zon, J. S.

10.1101/245225 — developmental biology — Posted on 2018-02-12

1132 Torso-like is a component of the hemolymph and regulates the insulin signalling pathway in Drosophila

Henstridge, M. A.; Aulsebrook, L.; Koyama, T.; Johnson, T. K.; Whisstock, J. C.; Tiganis, T.; Mirth, C. K.; Warr, C. G.

10.1101/264325 — developmental biology — Posted on 2018-02-12

1133 Tumour purity as a prognostic factor in colon cancer

Yihao, M.; Qingyang, F.; Peng, Z.; Liangliang, Y.; Tianyu, L.; Yuqiu, X.; Dexiang, Z.; Wenju, C.; Meiling, J.; Yongjiu, T.; Li, R.; Ye, W.; Guodong, H.; Jianmin, X.

10.1101/263723 — cancer biology — Posted on 2018-02-12

1134 Holmes-ITS2: Consolidated ITS2 resources and search engines for plant DNA-based marker analyses

Li, H.; Bai, H.; Yu, S.; Han, M.; Ning, K.

10.1101/263541 — bioinformatics — Posted on 2018-02-12

1135 Structure of a novel dimeric SET domain methyltransferase regulating cell motility

Pivovarova, Y.; Liu, J.; Lesigang, J.; Koldyka, O.; Rauschmeier, R.; Hu, K.; Dong, G.

10.1101/264291 — biochemistry — Posted on 2018-02-12

1136 Inflation versus filling-in: why we feel we see more than we actually do in peripheral vision

Odegaard, B.; Chang, M. Y.; Lau, H.; Cheung, S.-H.

10.1101/263244 — animal behavior and cognition — Posted on 2018-02-12

1137 High-throughput cancer hypothesis testing with an integrated PhysiCell-EMEWS workflow

Ozik, J.; Collier, N.; Wozniak, J.; Macal, C.; Cockrell, C.; Friedman, S.; Ghaffarizadeh, A.; Heiland, R.; An, G.; Macklin, P.

10.1101/196709 — systems biology — Posted on 2018-02-12

1138 Early mannitol-triggered changes in the Arabidopsis leaf (phospho)proteome

Nikonorova, N.; Van den Broeck, L.; Zhu, S.; van de Cotte, B.; Dubois, M.; Gevaert, K.; Inze, D.; De Smet, I.

10.1101/264259 — plant biology — Posted on 2018-02-12

1139 "Light-box" accelerated growth of poinsettias: LED-only Illumination

Weerasuriya, C.; Detez, S.; Ng, S. H.; Hughes, A.; Callaway, M.; Harrison, I.; Katkus, T.; Juodkazis, S.

10.1101/264168 — plant biology — Posted on 2018-02-12

1140 Extracting orthogonal subject- and behavior-specificsignatures from fMRI data using whole-brain effectiveconnectivity

Pallares, V.; Insabato, A.; Sanjuan, A.; Kuehn, S.; Mantini, D.; Deco, G.; Gilson, M.

10.1101/201624 — neuroscience — Posted on 2018-02-12

1141 The Aquilegia genome: adaptive radiation and an extraordinarily polymorphic chromosome with a unique history

Filiault, D.; Ballerini, E.; Mandakova, T.; Akoz, G.; Derieg, N.; Schmutz, J.; Jenkins, J.; Grimwood, J.; Shu, S.; Hayes, R.; Hellsten, U.; Barry, K.; Yan, J.; Mihaltcheva, S.; Karafiatova, M.; Nizhynska, V.; Lysak, M.; Hodges, S.; Nordborg, M.

10.1101/264101 — evolutionary biology — Posted on 2018-02-12

1142 Structural model of Cyc2, the primary electron acceptor of Acidithiobacillus ferrooxidans respiratory chain, as a modular cytochrome - β-barrel fusion protein, and mechanistic proposals based on this model

Abriata, L. A.

10.1101/262287 — biophysics — Posted on 2018-02-12

1143 HapCHAT: Adaptive haplotype assembly for efficiently leveraging high coverage in long reads

Beretta, S.; Patterson, M.; Marschall, T.; Martin, M.; Zaccaria, S.; Della Vedova, G.; Bonizzoni, P.

10.1101/170225 — bioinformatics — Posted on 2018-02-12

1144 Antimalarial pantothenamide metabolites target acetyl-CoA synthesis in Plasmodium falciparum

Schalkwijk, J.; Allman, E. L.; Jansen, P. A.; de Vries, L. E.; Jackowski, S.; Botman, P. N.; Beuckens-Schortinghuis, C. A.; Koolen, K. M.; Bolscher, J. M.; Vos, M. W.; Miller, K.; Reeves, S.; Pett, H.; Trevitt, G.; Wittlin, S.; Scheurer, C.; Sax, S.; Fischli, C.; Josling, G.; Kooij, T. W.; Bonnert, R.; Campo, B.; Blaauw, R. H.; Rutjes, F. P.; Sauerwein, R.; Llinas, M.; Hermkens, P. H.; Dechering, K. J.

10.1101/256669 — pharmacology and toxicology — Posted on 2018-02-12

1145 Large-scale, high-resolution comparison of the core visual object recognition behavior of humans, monkeys, and state-of-the-art deep artificial neural networks

Rajalingham, R.; Issa, E. B.; Bashivan, P.; Kar, K.; Schmidt, K.; DiCarlo, J. J.

10.1101/240614 — neuroscience — Posted on 2018-02-12

1146 PiFlow: A Low-Cost Programmable Dynamic Flow and Concentration System for Biological Stimulation Utilizing a Raspberry Pi and Commercial Piezoelectric Pumps

Kassis, T.; Perez, P. M.; Yang, C. J. W.; Soenksen, L. R.; Trumper, D. L.; Griffith, L. G.

10.1101/192047 — bioengineering — Posted on 2018-02-12

1147 Bacterial division FtsZ forms liquid condensates with nucleoid-associated Z-ring inhibitor SlmA

Monterroso, B.; Zorrilla, S.; Sobrinos-Sanguino, M.; Robles-Ramos, M. A.; Lopez-Alvarez, M.; Keating, C. D.; Rivas, G.

10.1101/264192 — biochemistry — Posted on 2018-02-12

1148 Working memory and reasoning benefit from different modes of large-scale brain dynamics in healthy older adults

Lebedev, A. V.; Nilsson, J.; Lovden, M.

10.1101/202630 — neuroscience — Posted on 2018-02-12

1149 Insights into Parkinson’s disease from computational models of the basal ganglia

Humphries, M.; Obeso, J.; Dreyer, J. K.

10.1101/260992 — neuroscience — Posted on 2018-02-12

1150 Aggregation recovers developmental plasticity in mouse polyploid embryos

Imai, H.; Fujii, W.; Kusakabe, K. T.; Kiso, Y.; Kano, K.

10.1101/263533 — developmental biology — Posted on 2018-02-12

1151 Cholesterol depletion by MβCD enhances membrane tension, its heterogeneity and affects cellular integrity.

Biswas, A.; Kashyap, P.; Datta, S.; Sengupta, T.; Sinha, B.

10.1101/264036 — biophysics — Posted on 2018-02-12

1152 Heat shock induces the depletion of Oct4 in mouse blastocysts and stem cells

Cheng, M.-b.; Wang, X.; Huang, Y.; Zhang, Y.

10.1101/264044 — molecular biology — Posted on 2018-02-12

1153 Genome-wide Association Study of Anxiety and Stress-related Disorders in the iPSYCH Cohort

Meier, S.; Trontti, K.; Als, T. D.; Laine, M.; Pedersen, M. G.; Bybjerg-Grauholm, J.; Hansen, M. B.; Sokolowska, E.; Mortensen, P. B.; Hougaard, D. M.; Werge, T.; Nordentoft, M.; Borglum, A.; Hovatta, I.; Mattheisen, M.; Mors, O.

10.1101/263855 — genetics — Posted on 2018-02-12

1154 Mechanistic insight into the interactions of NAP1 with NDP52 and TAX1BP1 for the recruitment of TBK1

Fu, T.; Liu, J.; Wang, Y.; Xie, X.; Hu, S.; Pan, L.

10.1101/264085 — biophysics — Posted on 2018-02-12

1155 Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies

10.1101/260281 — systems biology — Posted on 2018-02-11

1156 Epigenomic plasticity of Arabidopsis msh1mutants under prolonged cold stress

Kenchanmane Raju, S. K.; Shao, M.-R.; Wamboldt, Y.; Mackenzie, S.

10.1101/263780 — plant biology — Posted on 2018-02-11

1157 Chloroplasts of symbiotic microalgae remain active during bleaching induced by thermal stress in Collodaria (Radiolaria)

Villar, E.; Dani, V.; Bigeard, E.; Linhart, T.; Mendez-Sandin, M.; Bachy, C.; Six, C.; Lombard, F.; Sabourault, C.; Not, F.

10.1101/263053 — physiology — Posted on 2018-02-11

1158 Microbiota metabolic product deoxycholic acid controls chicken necrotic enteritis

Wang, H.; Latorre Cardenas, J. D.; Bansal, M.; Al-Rubaye, B.; Tellez, G.; Hargis, B.; Sun, X.

10.1101/215640 — microbiology — Posted on 2018-02-11

1159 Environmental determinants of pyoverdine production, exploitation and competition in natural Pseudomonas communities

Butaite, E.; Kramer, J.; Wyder, S.; Kuemmerli, R.

10.1101/263004 — microbiology — Posted on 2018-02-11

1160 Ancestry and Genetic Associations with Bronchopulmonary Dysplasia in Preterm Infants

Torgerson, D. G.; Ballard, P. L.; Keller, R. L.; Oh, S.; Huntsman, S.; Hu, D.; Eng, C.; Burchard, E. G.; Ballard, R. A.

10.1101/263814 — genetics — Posted on 2018-02-11

1161 A hierarchical Bayesian model for detecting convergent rate changes of conserved elements on phylogenetic trees

Hu, Z.; Sackton, T. B.; Edwards, S. V.; Liu, J. S.

10.1101/260745 — evolutionary biology — Posted on 2018-02-11

1162 Age-dependent dormant resident progenitors are stimulated by injury to regenerate Purkinje neurons

Bayin, N. S.; Wojcinski, A.; Mourton, A.; Saito, H.; Suzuki, N.; Joyner, A. L.

10.1101/263954 — developmental biology — Posted on 2018-02-11

1163 Structure of APP-C991-99 and Implications for Role of Extra-Membrane Domains in Function and Oligomerization

Pantelopulos, G.; Straub, J.; Thirumalai, D.; Sugita, Y.

10.1101/257469 — biophysics — Posted on 2018-02-11

1164 GTFtools: a Python package for analyzing various modes of gene models

Li, H.

10.1101/263517 — bioinformatics — Posted on 2018-02-11

1165 Culture-free generation of microbial genomes from human and marine microbiomes

Bishara, A.; Moss, E. L.; Kolmogorov, M.; Parada, A.; Weng, Z.; Sidow, A.; Dekas, A. E.; Batzoglou, S.; Bhatt, A. S.

10.1101/263939 — genomics — Posted on 2018-02-11

1166 A plug-and-play system for enzyme production at commercially viable levels in fed-batch cultures of Escherichia coli BL21 (DE3)

Sohoni, S.; Kundalia, P.; Shetty, A.; Vellore Sunder, A.; Gaikaiwari, R. P.; Wangikar, P. P.

10.1101/263582 — bioengineering — Posted on 2018-02-11

1167 miRNA profiling of primate cervicovaginal lavage and extracellular vesicles reveals miR-186-5p as a potential retroviral restriction factor in macrophages

Zhao, Z.; Muth, D. C.; Mulka, K.; Powell, B. H.; Hancock, G. V.; Liao, Z.; Metcalf Pate, K. A.; Witwer, K. W.

10.1101/263947 — molecular biology — Posted on 2018-02-11

1168 Long time-scales in primate amygdala neurons support aversive learning

Taub, A. H.; Stolero, T.; Livneh, U.; Shohat, Y.; Paz, R.

10.1101/263889 — neuroscience — Posted on 2018-02-11

1169 Herpes ICP8 protein stimulates homologous recombination in human cells

Valledor, M.; Myers, R. S.; Schiller, P. C.

10.1101/259739 — molecular biology — Posted on 2018-02-11

1170 Nuclear envelope assembly defects link mitotic errors to chromothripsis

Liu, S.; Kwon, M.; Mannino, M.; Yang, N.; Khodjakov, A.; Pellman, D.

10.1101/263392 — cell biology — Posted on 2018-02-11

1171 Single-cell transcriptome of antler stem cells from antlerogenic periosteum

Ba, H.; Wang, D.; Wu, W.; Sun, H.; Li, C.

10.1101/263798 — cell biology — Posted on 2018-02-11

1172 Photon yield enhancement of red fluorophores at cryogenic temperatures

Hulleman, C. N.; Li, W.; Gregor, I.; Rieger, B.; Enderlein, J.

10.1101/263848 — biophysics — Posted on 2018-02-11

1173 Validation and Topic-driven Ranking for Biomedical Hypothesis Generation Systems

Sybrandt, J.; Safro, I.

10.1101/263897 — bioinformatics — Posted on 2018-02-11

1174 The variability of song variability in wild and domesticated zebra finches Taeniopygia guttata

Lansverk, A. L.; London, S. E.; Griffith, S. C.; Clayton, D. F.; Balakrishnan, C. N.

10.1101/263913 — animal behavior and cognition — Posted on 2018-02-11

1175 The genome of the water strider Gerris buenoi reveals expansions of gene repertoires associated with adaptations to life on the water

Armisen, D.; Rajakumar, R.; Friedrich, M.; Benoit, J. B.; Robertson, H. M.; Panfilio, K. A.; Ahn, S.-J.; Poelchau, M. F.; Chao, H.; Dinh, H.; Doddapaneni, H.; Dugan-Perez, S.; Gibbs, R. A.; Hughes, D. S.; Han, Y.; Lee, S. L.; Murali, S. C.; Muzny, D. M.; Qu, J.; Worley, K. C.; Munoz-Torres, M.; Abouheif, E.; Bonneton, F.; Chen, T.; Chiang, L.-M.; Childers, C. P.; Cridge, A. G.; Crumiere, A. J.; Decaras, A.; Didion, E. M.; Duncan, E.; Elpidina, E. N.; Fave, M.-J.; Finet, C.; Jacobs, C. G.; Jarvela, A.; Jennings, E. J.; Jones, J. W.; Lesoway, M. P.; Lovegrove, M.; Martynov, A.; Oppert, B.; Lilic

10.1101/242230 — genomics — Posted on 2018-02-11

1176 DNA methylation dynamics during embryonic development and postnatal maturation of the mouse auditory organ of Corti

Yizhar-Barnea, O.; Valensisi, C.; Kishore, K.; Jayavelu, N. D.; Andrus, C.; Koffler-Brill, T.; Ushakov, K.; Perl, K.; Noy, Y.; Bhonker, Y.; Pelizzola, M.; Hawkins, R. D.; Avraham, K. B.

10.1101/262832 — genomics — Posted on 2018-02-11

1177 First nuclear genome assembly of an extinct moa species, the little bush moa (Anomalopteryx didiformis)

Cloutier, A.; Sackton, T. B.; Grayson, P.; Edwards, S. V.; Baker, A. J.

10.1101/262816 — evolutionary biology — Posted on 2018-02-11

1178 Gene expression in cord blood links genetic risk for neurodevelopmental disorders with maternal psychological distress and adverse childhood outcomes

Breen, M. S.; Wingo, A. P.; Koen, N.; Donald, K. A.; Nicol, M.; Zar, H. J.; Ressler, K. J.; Buxbaum, J. D.; Stein, D. J.

10.1101/216309 — developmental biology — Posted on 2018-02-11

1179 Recapitulation of human germline coding variation in an ultra-mutated infant leukemia

Gout, A. M.; Kotecha, R. S.; Kaur, P.; Abad, A.; Foley, B.; Carter, K. W.; Cole, C. H.; Bond, C. S.; Kees, U. R.; Waithman, J.; Cruickshank, M. N.

10.1101/248690 — cancer biology — Posted on 2018-02-11

1180 Correcting for batch effects in case-control microbiome studies

Gibbons, S.; Duvallet, C.; Alm, E. J.

10.1101/165910 — bioinformatics — Posted on 2018-02-11

1181 Example of Methylome Analysis with MethylIT using Cancer Datasets

Sanchez, R.; Mackenzie, S.

10.1101/261982 — bioinformatics — Posted on 2018-02-11

1182 Forget Pixels: Adaptive Particle Representation of Fluorescence Microscopy Images

Cheeseman, B. L.; Günther, U.; Susik, M.; Gonciarz, K.; Sbalzarini, I. F.

10.1101/263061 — bioinformatics — Posted on 2018-02-11

1183 Chromosome assembly of large and complex genomes using multiple references

Kolmogorov, M.; Armstrong, J.; Raney, B. J.; Streeter, I.; Dunn, M.; Yang, F.; Odom, D.; Flicek, P.; Keane, T.; Thybert, D.; Paten, B.; Pham, S.

10.1101/088435 — bioinformatics — Posted on 2018-02-11

1184 Postsynaptic Pannexin-1 Facilitates Anandamide Uptake to Modulate Glutamate Release and Enhance Network Excitability

Bialecki, J.; Weilinger, N. L.; Lohman, A. W.; Vecchiarelli, H. A.; Robinsons, J. H.; Egana, J.; Medizabal-Zubiaga, J.; Werner, A. C.; Grandes, P.; Teskey, G. C.; Hill, M. N.; Thompson, R. J.

10.1101/263640 — neuroscience — Posted on 2018-02-11

1185 Conserved Roles of C. elegans and Human MANFs in Sulfatide Binding and Cytoprotection

Bai, M.; Vozdek, R.; Hnizda, A.; Jiang, C.; Wang, B.; Kuchar, L.; Li, T.; Zhang, Y.; Wood, C.; Feng, L.; Dang, Y.; Ma, D. K.

10.1101/263731 — cell biology — Posted on 2018-02-11

1186 Structural insights into the recognition of mono- and di-acetyllysine by the ATAD2B bromodomain

Lloyd, J. T.; Gay, J. C.; Tonelli, M.; Cornilescu, G.; Nguyen, P.; Carlson, S.; Markley, J. L.; Glass, K. C.

10.1101/263624 — biochemistry — Posted on 2018-02-11

1187 RAD51 Enhances Zygotic Interhomolog Repair

Wilde, J. J.; Aida, T.; Wienisch, M.; Zhang, Q.; Qi, P.; Feng, G.

10.1101/263699 — molecular biology — Posted on 2018-02-11

1188 Experimental Evolution of Cell Shape in Bacteria

Yulo, P. R.; Desprat, N.; Gerth, M. L.; Liu, Y.; Zhang, X.-X.; Rainey, P. B.; Hendrickson, H. L.

10.1101/263681 — microbiology — Posted on 2018-02-11

1189 Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP pathways in macrophages

Muse, E. D.; Yu, S.; Edillor, C. R.; Tao, J.; Spann, N. J.; Troutman, T. D.; Seidman, J. S.; Henke, A.; Roland, J. T.; Ozeki, K. A.; McDonald, J. G.; Bahadorani, J.; Tsimikas, S.; Grossman, T. R.; Tremblay, M. S.; Glass, C. K.

10.1101/263434 — cell biology — Posted on 2018-02-11

1190 CD117/c-kit in Cancer Stem Cell-Mediated Progression and Therapeutic Resistance

Foster, B. M.; Zaidi, D.; Young, T. R.; Mobley, M. E.; Kerr, B. A.

10.1101/256099 — cancer biology — Posted on 2018-02-11

1191 Computational modeling highlights disordered Formin Homology 1 domain’s role in profilin-actin transfer

Horan, B.; Zerze, G.; Kim, Y. C.; Vavylonis, D.; Mittal, J.

10.1101/263566 — biophysics — Posted on 2018-02-11

1192 A death pheromone, oleic acid, triggers hygienic behavior in honey bees (Apis mellifera L.)

McAfee, A.; Chapman, A.; Iovinella, I.; Gallagher-Kurtzke, Y.; Collins, T. F.; Higo, H.; Madilao, L. L.; Pelosi, P.; Foster, L. J.

10.1101/231902 — animal behavior and cognition — Posted on 2018-02-10

1193 The Autoimmune Disease Risk Allele rs6897932 Modulates Monocyte IL7R Surface and Soluble Receptor Levels in a Context-Specific Manner

Al-Mossawi, H.; Lau, E.; Danielli, S.; de Wit, J.; Makino, S.; Yager, N.; Gilchrist, J.; Lee, W.; Nassiri, I.; Mahe, E. A.; Rizvi, L.; Cheeseman, J.; Neville, M.; Knight, J. C.; Bowness, P.; Fairfax, B. P.

10.1101/262410 — immunology — Posted on 2018-02-10

1194 Properties of Gene Expression and Chromatin Structure with Mechanically Regulated Transcription

Sevier, S. A.; Levine, H.

10.1101/262717 — biophysics — Posted on 2018-02-10

1195 ANIMA: Association Network Integration for Multiscale Analysis

Deffur, A.; Wilkinson, R. J.; Mayosi, B. M.; Mulder, N. M.

10.1101/257642 — systems biology — Posted on 2018-02-10

1196 Absence of receptor guanylyl cyclase C enhances ileal damage and reduces cytokine and antimicrobial peptide production during oral Salmonella Typhimurium infection

Majumdar, S.; Mishra, V.; Nandi, S.; Abdullah, M.; Barman, A.; Raghavan, A.; Nandi, D.; Visweswariah, S. S.

10.1101/214163 — microbiology — Posted on 2018-02-10

1197 The summary diagram of discovered host immunological pathways against different pathogens and its relation to hypersensitivities

Hu, W.

10.1101/006965 — immunology — Posted on 2018-02-10

1198 An agent-based model of cattle grazing toxic Geyer’s larkspur

Jablonski, K.; Boone, R. B.; Meiman, P. J.

10.1101/218032 — ecology — Posted on 2018-02-10

1199 Recapitulation of human germline coding variation in an ultra-mutated infant leukemia

Gout, A. M.; Kotecha, R. S.; Kaur, P.; Abad, A.; Foley, B.; Carter, K. W.; Cole, C. H.; Bond, C. S.; Kees, U. R.; Waithman, J.; Cruickshank, M. N.

10.1101/248690 — cancer biology — Posted on 2018-02-10

1200 CITGeneDB: A comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice

Li, J.; Deng, S.-P.; Wei, G.; Yu, P.

10.1101/250514 — bioinformatics — Posted on 2018-02-10

1201 Cornelia de Lange Syndrome-associated mutations in Smc1 cause both sister chromatid cohesion and cohesion-independent defects

Chen, J.; Wu, M.; Dawson, D.; Rankin, S.

10.1101/263418 — genetics — Posted on 2018-02-10

1202 A critical role for Dna2 at unwound telomeres

Lydall, D.; Lisby, M.; Markiewicz-Potoczny, M.

10.1101/263228 — genetics — Posted on 2018-02-10

1203 Competitive release in tumors

Ma, Y.; West, J.; Newton, P. K.

10.1101/263335 — cancer biology — Posted on 2018-02-10

1204 Optimizing chemo-scheduling based on tumor growth rates

West, J.; Newton, P. K.

10.1101/263327 — cancer biology — Posted on 2018-02-10

1205 Multi-Omic Profiling Reveals the Opposing Forces of Excess Dietary Sugar and Fat on Liver Mitochondria Protein Acetylation and Succinylation

Meyer, J. G.; Softic, S.; Basisty, N.; Rardin, M. J.; Verdin, E.; Gibson, B. W.; Ilkayeva, O.; Newgard, C.; Kahn, C. R.; Schilling, B.

10.1101/263426 — systems biology — Posted on 2018-02-10

1206 DNA methylation dynamics during embryonic development and postnatal maturation of the mouse auditory organ of Corti

Avraham, K. B.; Yizhar-Barnea, O.; Valensisi, C.; Kishore, K.; Jayavelu, N. D.; Andrus, C.; Koffler-Brill, T.; Ushakov, K.; Perl, K.; Noy, Y.; Bhonker, Y.; Pelizzola, M.; Hawkins, R. D.

10.1101/262832 — genomics — Posted on 2018-02-10

1207 Long-read sequencing across the C9orf72 ‘GGGGCC’ repeat expansion: implications for genetic discovery efforts in human disease

Ebbert, M. T. W.; Farrugia, S.; Sens, J.; Jansen-West, K.; Gendron, T.; Prudencio, M.; DeJesus-Hernandez, M.; Brown, P.; Dickson, D.; van Blitterswijk, M.; Rademakers, R.; Petrucelli, L.; Fryer, J. D.

10.1101/176651 — genetics — Posted on 2018-02-10

1208 Reciprocal F1 hybrids of two inbred mouse strains reveal parent-of-origin and perinatal diet effects on behavior and expression

Oreper, D. G.; Schoenrock, S.; McMullan, R.; Ervin, R.; Farrington, J.; Miller, D. R.; Pardo-Manuel de Villena, F.; Valdar, W.; Tarantino, L.

10.1101/262642 — genetics — Posted on 2018-02-10

1209 New insights on adaptation and population structure of cork oak using genotyping by sequencing

Pina-Martins, F.; Baptista, J.; Pappas, G.; Paulo, O. S.

10.1101/263160 — evolutionary biology — Posted on 2018-02-10

1210 Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages

Yang, J.; Mott, D.; Sutiwisesak, R.; Lu, Y. J.; Rosa, F.; Stowell, B.; Babunovic, G.; Lee, J.; Carpenter, S.; Way, S. S.; Fortune, S.; Behar, S. M.

10.1101/262493 — immunology — Posted on 2018-02-10

1211 Shugoshin protects centromere pairing and promotes segregation of non-exchange partner chromosomes in meiosis

Previato, L.; Kurdzo, E. L.; Eyster, C. A.; Gladstone, M. N.; Chuong, H. H.; Llano, E.; Pendas, A. M.; Pezza, R. J.; Dawson, D. S.

10.1101/263384 — cell biology — Posted on 2018-02-10

1212 Structure of the 30S ribosomal decoding complex at ambient temperature

Dao, E. H.; Poitevin, F.; Sierra, R. G.; Gati, C.; Rao, Y.; Ciftci, H. I.; Aksit, F.; McGurk, A.; Obrinski, T.; Mgbam, P.; Hayes, B.; de Lichtenberg, C.; Pardo-Avila, F.; Corsepius, N.; Zhang, L.; Seaberg, M.; Hunter, M. S.; Liang, M.; Koglin, J. E.; Wakatsuki, S.; Demirci, H.

10.1101/262972 — biophysics — Posted on 2018-02-10

1213 Zinc(II) binding on human wild-type ISCU and Met140 variants modulates Fe-S complex activity

Fox, N. G.; Martelli, A.; Nabhan, J. F.; Janz, J.; Borkowska, O.; Bulawa, C.; Yue, W.

10.1101/262477 — biochemistry — Posted on 2018-02-10

1214 Ultrastructure of salivary glands in Psammotettix alienus Dahlbom (Homoptera: Cicadellidae) infected with Taastrup virus

Lundsgaard, T.

10.1101/263194 — cell biology — Posted on 2018-02-10

1215 Substrate conformational dynamics drive structure-specific recognition of gapped DNA by DNA polymerase

Craggs, T. D.; Sustarsic, M.; Plochowietz, A.; Mosayebi, M.; Kaju, H.; Cuthbert, A.; Hohlbein, J.; Domicevica, L.; Biggin, P. C.; Doye, J. P. K.; Kapanidis, A. N.

10.1101/263038 — biophysics — Posted on 2018-02-10

1216 Spatio-temporal relays control layer specificity of motion-direction sensitive neurons in Drosophila

Apitz, H.; Salecker, I.

10.1101/262451 — neuroscience — Posted on 2018-02-10

1217 Properties of Gene Expression and Chromatin Structure with Mechanically Regulated Transcription

Sevier, S. A.; Levine, H.

10.1101/262717 — biophysics — Posted on 2018-02-10

1218 Single day construction of multi-gene circuits with 3G assembly

Halleran, A. D.; Swaminathan, A.; Murray, R. M.

10.1101/260851 — bioengineering — Posted on 2018-02-10

1219 Activations of Deep Convolutional Neural Network are Aligned with Gamma Band Activity of Human Visual Cortex

Kuzovkin, I.; Vicente, R.; Petton, M.; Lachaux, J.-P.; Baciu, M.; Kahane, P.; Rheims, S.; Vidal, J. R.; Aru, J.

10.1101/133694 — neuroscience — Posted on 2018-02-09

1220 Spike-timing pattern operates as gamma-distribution across cell types, regions and animal species and is essential for naturally-occurring cognitive states

Li, M.; Xie, K.; Kuang, H.; Liu, J.; Wang, D.; Fox, G. E.; Wei, W.; Li, X.; Li, Y.; Zhao, F.; Chen, L.; Shi, Z.; Cui, H.; Mao, Y.; Tsien, J. Z.

10.1101/145813 — neuroscience — Posted on 2018-02-09

1221 Deep convolutional and recurrent neural networks for cell motility discrimination and prediction

Kimmel, J.; Brack, A.; Marshall, W. F.

10.1101/159202 — bioinformatics — Posted on 2018-02-09

1222 Kinetics of winter deacclimation in response to temperature determines dormancy status and explains budbreak in different Vitis species

Kovaleski, A. P.; Reisch, B. I.; Londo, J. P.

10.1101/256362 — plant biology — Posted on 2018-02-09

1223 A Diverse Range of Factors Affect the Nature of Neural Representations Underlying Short-Term Memory

Orhan, E.; Ma, W. J.

10.1101/244707 — neuroscience — Posted on 2018-02-09

1224 riboSeed: leveraging prokaryotic genomic architecture to assemble across ribosomal regions

Waters, N. R.; Abram, F.; Brennan, F.; Holmes, A.; Pritchard, L.

10.1101/159798 — bioinformatics — Posted on 2018-02-09

1225 Effects of mRNA degradation and site-specific transcriptional pausing on protein expression noise

Kim, S.; Jacobs-Wagner, C.

10.1101/210401 — systems biology — Posted on 2018-02-09

1226 Prolonged reductions in cortical blood flow and tissue oxygen tension do not contribute to the activation and mechanical sensitization of meningeal afferents following CSD

Zhao, J.; Levy, D.

10.1101/149278 — neuroscience — Posted on 2018-02-09

1227 Three-stage processing of category and variation information by entangled interactive mechanisms of peri-occipital and peri-frontal cortices

Karimi-Rouzbahani, H.

10.1101/189811 — neuroscience — Posted on 2018-02-09

1228 An accumulation-of-evidence task using visual pulses for mice navigating in virtual reality

Pinto, L.; Koay, S. A.; Engelhard, B.; Yoon, A. M.; Deverett, B.; Thiberge, S. Y.; Witten, I.; Tank, D. W.; Brody, C.

10.1101/232702 — neuroscience — Posted on 2018-02-09

1229 Needle in a haystack? A comparison of eDNA metabarcoding and targeted qPCR for detection of great crested newt (Triturus cristatus)

Harper, L. R.; Lawson Handley, L.; Hahn, C.; Boonham, N.; Rees, H. C.; Gough, K. C.; Lewis, E.; Adams, I. P.; Brotherton, P.; Phillips, S.; Haenfling, B.

10.1101/215897 — molecular biology — Posted on 2018-02-09

1230 Improved imputation of summary statistics for realistic settings

Rüeger, S.; McDaid, A.; Kutalik, Z.

10.1101/203927 — genomics — Posted on 2018-02-09

1231 Subtle left-right asymmetry of gene expression profiles in embryonic and foetal human brains

de Kovel, C. G. F.; Lisgo, S. N.; Fisher, S. E.; Francks, C.

10.1101/263111 — genomics — Posted on 2018-02-09

1232 Building a schizophrenia genetic network: Transcription Factor 4 regulates genes involved in neuronal development and schizophrenia risk.

Xia, H.; Jahr, F. M.; Kim, N.-K.; Xie, L.; Shabalin, A. A.; Bryois, J.; Sweet, D. H.; Kronfol, M. M.; Palasuberniam, P.; McRae, M.; Riley, B. P.; Sullivan, P. F.; van den Oord, E. J.; McClay, J.

10.1101/215715 — genetics — Posted on 2018-02-09

1233 Forget Pixels: Adaptive Particle Representation of Fluorescence Microscopy Images

Cheeseman, B. L.; Günther, U.; Susik, M.; Gonciarz, K.; Sbalzarini, I. F.

10.1101/263061 — bioinformatics — Posted on 2018-02-09

1234 Effects of coil orientation on Motor Evoked Potentials from Orbicularis Oris and First Dorsal Interosseous

Adank, P.; Kennedy-Higgins, D.; Maegherman, G.; Hannah, R.; Nuttal, H. E.

10.1101/262261 — neuroscience — Posted on 2018-02-09

1235 Whole-genome analyses resolve the phylogeny of flightless birds (Palaeognathae) in the presence of an empirical anomaly zone

Cloutier, A.; Sackton, T. B.; Grayson, P.; Clamp, M.; Baker, A. J.; Edwards, S. V.

10.1101/262949 — evolutionary biology — Posted on 2018-02-09

1236 First nuclear genome assembly of an extinct moa species, the little bush moa (Anomalopteryx didiformis)

Cloutier, A.; Sackton, T. B.; Grayson, P.; Edwards, S. V.; Baker, A. J.

10.1101/262816 — evolutionary biology — Posted on 2018-02-09

1237 Bayesian multi-scale modeling of macromolecular structures based on cryo-electron microscopy density maps

Hanot, S.; Bonomi, M.; Greenberg, C. H.; Sali, A.; Nilges, M.; Vendruscolo, M.; Pellarin, R.

10.1101/113951 — bioinformatics — Posted on 2018-02-09

1238 Sustained release and pharmacologic effects of human glucagon-like peptide-1 and liraglutide from polymeric microparticles.

Icart, L. P.; Souza, F. G.; Lima, L. M.

10.1101/262782 — pharmacology and toxicology — Posted on 2018-02-09

1239 Neutralizing Gatad2a-Chd4-Mbd3 Axis within the NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency

Mor, N.; Rais, Y.; Peles, S.; Sheban, D.; Aguilera-Castrejon, A.; Zviran, A.; Elinger, D.; Viukov, S.; Geula, S.; Krupalnik, V.; Zerbib, M.; Chomsky, E.; Lasman, L.; Shani, T.; Bayerl, J.; Gafni, O.; Hanna, S.; Buenrostro, J.; Hagai, T.; Masika, H.; Bergman, Y.; Greenleaf, W. J.; Esteban, M. A.; Levin, Y.; Massarwa, R.; Merbl, Y.; Novershtern, N.; Hanna, J. H.

10.1101/192781 — developmental biology — Posted on 2018-02-09

1240 TCR-MHC Interaction Strength Defines Trafficking and Resident Memory Status of CD8 T cells in the Brain

Sanecka, A.; Yoshida, N.; Kolawole, E. M.; Patel, H.; Evavold, B. D.; Frickel, E.

10.1101/263152 — immunology — Posted on 2018-02-09

1241 Cell-matrix adhesion controls Golgi organization and function by regulating Arf1 activation in anchorage-dependent cells.

Singh, V.; Erady, C.; Balasubramanian, N.

10.1101/261842 — cell biology — Posted on 2018-02-09

1242 Specific Eph Receptor-Cytoplasmic Effector Signaling Mediated by SAM-SAM Domain Interactions

Zhang, M.; Wang, Y.; Shang, Y.; Li, J.; Chen, W.; Li, G.; Wan, J.; Liu, W.

10.1101/263137 — biophysics — Posted on 2018-02-09

1243 No unexpected CRISPR-Cas9 off-target activity revealed by trio sequencing of gene-edited mice

Iyer, V.; Boroviak, K.; Thomas, M.; Doe, B.; Ryder, E.; Adams, D.

10.1101/263129 — bioengineering — Posted on 2018-02-09

1244 Clonal Level Lineage Commitment Pathways of Hematopoietic Stem Cells In Vivo

Lu, R.; Czechowicz, A.; Seita, J.; Jiang, D.; Weissman, I. L.

10.1101/262774 — systems biology — Posted on 2018-02-09

1245 Highly efficient CRISPR gene editing in yeast enabled by double selection

Despres, P. C.; Dube, A. K.; Nielly-Thibault, L.; Yachie, N.; Landry, C. R.

10.1101/262808 — synthetic biology — Posted on 2018-02-09

1246 Distinct Neural Signatures of Reward and Sensory Prediction Error in Motor Learning

Palidis, D. J.; Cashaback, J.; Gribble, P.

10.1101/262576 — neuroscience — Posted on 2018-02-09

1247 The relationship between brain atrophy and cognitive-behavioral symptoms in retired Canadian football players with multiple concussions

Misquitta, K.; Dadar, M.; Tarazi, A.; Hussain, M. W.; Alatwi, M. K.; Ebraheem, A.; Multani, N.; Khodadadi, M.; Goswami, R.; Wennberg, R.; Tator, C.; Green, R.; Colella, B.; Davis, K.; Mikulis, D.; Grinberg, M.; Sato, C.; Rogaeva, E.; Collins, L.; Tartaglia, M. C.

10.1101/261404 — neuroscience — Posted on 2018-02-09

1248 A closed-loop hand prosthesis with simultaneous intraneural tactile and position feedback

D'Anna, E.; Valle, G.; Mazzoni, A.; Strauss, I.; Ibertie, F.; Patton, J.; Petrini, F.; Raspopovic, S.; Granata, G.; Di Iorio, R.; Controzzi, M.; Cipriani, C.; Stieglitz, T.; Rossini, P.; Micera, S.

10.1101/262741 — neuroscience — Posted on 2018-02-09

1249 Haploinsufficiency of autism candidate gene NUAK1 impairs cortical development and behavior

Courchet, V.; Roberts, A. J.; Del Carmine, P.; Lewis, T. L.; Polleux, F.; Courchet, J.

10.1101/262725 — neuroscience — Posted on 2018-02-09

1250 Sensations from a single M-cone depend on the activity of surrounding S-cones

Schmidt, B. P.; Sabesan, R.; Tuten, W. S.; Neitz, J.; Roorda, A.

10.1101/260653 — neuroscience — Posted on 2018-02-09

1251 Complex evolutionary history of translation Elongation Factor 2 and diphthamide biosynthesis in Archaea and parabasalids

Narrowe, A. B.; Spang, A.; Stairs, C. W.; Caceres, E. F.; Baker, B. J.; Miller, C. S.; Ettema, T. J. G.

10.1101/262600 — microbiology — Posted on 2018-02-09

1252 Functional Improbable Antibody Mutations Critical for HIV Broadly Neutralizing Antibody Development

Wiehe, K.; Bradley, T.; Meyerhoff, R. R.; Hart, C.; Williams, W.; Easterhoff, D.; Faison, W. J.; Kepler, T. B.; Saunders, K. O.; Alam, S. M.; Bonsignori, M.; Haynes, B. F.

10.1101/262592 — immunology — Posted on 2018-02-09

1253 Integrative analysis of transcription factor occupancy at enhancers and disease risk loci in noncoding genomic regions

Oki, S.; Ohta, T.; Shioi, G.; Hatanaka, H.; Ogasawara, O.; Okuda, Y.; Kawaji, H.; Nakaki, R.; Sese, J.; Meno, C.

10.1101/262899 — genomics — Posted on 2018-02-09

1254 SMRT-Cappable-seq reveals complex operon variants in bacteria

Yan, B.; Boitano, M.; Clark, T.; Ettwiller, L.

10.1101/262964 — genomics — Posted on 2018-02-09

1255 First nuclear genome assembly of an extinct moa species, the little bush moa (Anomalopteryx didiformis)

Cloutier, A.; Sackton, T. B.; Grayson, P.; Edwards, S. V.; Baker, A. J.

10.1101/262816 — evolutionary biology — Posted on 2018-02-09

1256 Conserved accessory proteins encoded with archaeal and bacterial Type III CRISPR-Cas gene cassettes that may specifically modulate, complement or extend interference activity

Shah, S. A.; Alkhnbashi, O. S.; Behler, J.; Han, W.; She, Q.; Hess, W. R.; Garrett, R. A.; Backofen, R.

10.1101/262675 — bioinformatics — Posted on 2018-02-09

1257 TFmapper: A tool for searching putative factors regulating gene expression using ChIP-seq data

Zeng, J.; Li, G.

10.1101/262923 — bioinformatics — Posted on 2018-02-09

1258 KrakenHLL: Confident and fast metagenomics classification using unique k-mer counts

Breitwieser, F. P.; Salzberg, S. L.

10.1101/262956 — bioinformatics — Posted on 2018-02-09

1259 A folded viral noncoding RNA blocks host cell exoribonucleases through programmed remodeling of RNA structure

Steckelberg, A.-L.; Akiyama, B. M.; Costantino, D. A.; Sit, T. L.; Nix, J. C.; Kieft, J. S.

10.1101/262683 — biochemistry — Posted on 2018-02-09

1260 Network dimensionality underlies flexible representation of cognitive information

Ito, T.; Cole, M. W.

10.1101/262626 — neuroscience — Posted on 2018-02-09

1261 Evolutionary trajectories to amoxicillin-clavulanic acid resistance in Escherichia coli are affected by growth media.

Hubbard, A. T.; Feasey, N. A.; Roberts, A. P.

10.1101/262691 — microbiology — Posted on 2018-02-09

1262 Phylogenomic analyses resolve historically contentious relationships within the Palaeognathae in the presence of an empirical anomaly zone

Cloutier, A.; Sackton, T. B.; Grayson, P.; Clamp, M.; Baker, A. J.; Edwards, S. V.

10.1101/262949 — evolutionary biology — Posted on 2018-02-09

1263 Accelerated brain aging towards transcriptional inversion in a zebrafish model of familial Alzheimer’s disease

Hin, N.; Newman, M.; Kaslin, J.; Douek, A. M.; Lumsden, A.; Zhou, X.-F.; Manucat-Tan, N. B.; Ludington, A.; Adelson, D. L.; Pederson, S.; Lardelli, M.

10.1101/262162 — bioinformatics — Posted on 2018-02-09

1264 Example of Methylome Analysis with MethylIT using Cancer Datasets

Sanchez, R.

10.1101/261982 — bioinformatics — Posted on 2018-02-09

1265 PET Brain imaging of α7-nAChR with ASEM: Reproducibility, occupancy, receptor density, and changes in schizophrenia

Wong, D. F.; Kuwabara, H.; Horti, A. G.; Roberts, J.; Nandi, A.; Cascella, N.; Brasic, J. R.; Weerts, E.; Kitzmiller, K.; Phan, J. A.; Gapasin, L.; Sawa, A.; Valentine, H.; Wand, G.; George, N.; McDonald, M.; Kem, W.; Freedman, R.; Gjedde, A.

10.1101/245118 — neuroscience — Posted on 2018-02-08

1266 Microfluidics for Electrophysiology, Imaging, and Behavioral Analysis of Hydra

Badhiwala, K. N.; Gonzales, D. L.; Vercosa, D. G.; Avants, B. W.; Robinson, J. T.

10.1101/257691 — neuroscience — Posted on 2018-02-08

1267 Mapping diversification metrics in macroecological studies: Prospects and challenges

Velasco, J. A.; Pinto Ledezma, J. N.

10.1101/261867 — ecology — Posted on 2018-02-08

1268 Riding the Cell Jamming Boundary: Geometry, Topology, and Phase of Human Corneal Endothelium

Brookes, N. H.

10.1101/236406 — biophysics — Posted on 2018-02-08

1269 Computational model of chimeric antigen receptors explains site-specific phosphorylation kinetics

Rohrs, J. A.; Zheng, D.; Graham, N. A.; Wang, P.; Finley, S.

10.1101/262527 — systems biology — Posted on 2018-02-08

1270 Functional analysis of African Xanthomonas oryzae pv. oryzae TALomes reveals a new susceptibility gene in bacterial leaf blight of rice

Tran, T. T.; Perez-Quintero, A. L.; Wonni, I.; Carpenter, S. C. D.; Yu, Y.; Wang, L.; Leach, J. E.; Verdier, V.; Cunnac, S.; Bogdanove, A. J.; Koebnik, R.; Hutin, M.; Szurek, B.

10.1101/261313 — plant biology — Posted on 2018-02-08

1271 Diet Modifies Colonic Microbiota and CD4+ T cell Repertoire to Trigger Flares in a Novel Model of Colitis Induced by IL-23

Chen, L.; He, Z.; Iuga, A. C.; Filho, S. M.; Faith, J. J.; Clemente, J. C.; Deshpande, M.; Jayaprakash, A.; Colombel, J.-F.; Lafaille, J. J.; Sachidanandam, R.; Furtado, G. C.; Lira, S. A.

10.1101/262634 — immunology — Posted on 2018-02-08

1272 Longitudinal immunosequencing in healthy people reveals persistent T cell receptors rich in public receptors

Chu, N. D.; Bi, H. S.; Emerson, R. O.; Sherwood, A. M.; Birnbaum, M. E.; Robins, H. S.; Alm, E. J.

10.1101/262667 — immunology — Posted on 2018-02-08

1273 Generative adversarial networks uncover epidermal regulators and predict single cell perturbations

Ghahramani, A.; Watt, F. M.; Luscombe, N. M.

10.1101/262501 — genomics — Posted on 2018-02-08

1274 Shared Nucleotide Flanks Confer Transcriptional Competency to bZip Core Motifs

Cohen, D. M.; Lim, H.-W.; Won, K. J.; Steger, D. J.

10.1101/262659 — genomics — Posted on 2018-02-08

1275 Assessment of DNA methylation patterns in the bone and cartilage of a nonhuman primate model of osteoarthritis

Housman, G.; Havill, L. M.; Quillen, E. E.; Comuzzie, A. G.; Stone, A. C.

10.1101/184879 — genetics — Posted on 2018-02-08

1276 Absence of the Spindle Assembly Checkpoint restores mitotic fidelity upon loss of sister chromatid cohesion

Silva, R. D.; Mirkovic, M.; Guilgur, L. G.; Rathore, O. S.; Martinho, R. G.; Oliveira, R. A.

10.1101/262204 — cell biology — Posted on 2018-02-08

1277 A normalized drug response metric improves accuracy and consistency of drug sensitivity quantification in cell-based screening

Gupta, A.; Gautam, P.; Wennerberg, K.; Aittokallio, T.

10.1101/262568 — bioinformatics — Posted on 2018-02-08

1278 Engineering of new-to-nature halogenated indigo precursors in plants

Frabel, S.; Wagner, B.; Krischke, M.; Schmidts, V.; Thiele, C. M.; Staniek, A.; Warzecha, H.

10.1101/262428 — synthetic biology — Posted on 2018-02-08

1279 Functional analysis of African Xanthomonas oryzae pv. oryzae TALomes reveals a new susceptibility gene in bacterial leaf light of rice

Tran, T. T.; Perez-Quintero, A. L.; Wonni, I.; Carpenter, S. C. D.; Yu, Y.; Wang, L.; Leach, J. E.; Verdier, V.; Cunnac, S.; Bogdanove, A. J.; Koebnik, R.; Hutin, M.; Szurek, B.

10.1101/261313 — plant biology — Posted on 2018-02-08

1280 Effects of different load on physiological, hematological, biochemical, cytokines indices of Zanskar ponies at high altitude

Vivek, P.; Bharti, V. K.; Kumar, D.; Kumar, R.; Nehra, K.; Singh, D.; Chaurasia, O. P.; Kumar, B.

10.1101/262253 — physiology — Posted on 2018-02-08

1281 2,4-Diaminothienopyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm

Partridge, F. A.; Forman, R.; Willis, N. J.; Bataille, C. J.; Murphy, E. A.; Brown, A. E.; Heyer-Chauhan, N.; Marinic, B.; Sowood, D. J.; Wynne, G. M.; Else, K. J.; Russell, A. J.; Sattelle, D. B.

10.1101/254037 — pharmacology and toxicology — Posted on 2018-02-08

1282 Neuroligins mediate presynaptic maturation through brain-derived neurotrophic factor signaling

Petkova, A.; Goedecke, N.; Korte, M.; Dresbach, T.

10.1101/262246 — neuroscience — Posted on 2018-02-08

1283 Transcranial focused ultrasound neuromodulation of the human primary motor cortex

Legon, W.; Bansal, P.; Tyshynsky, R.; Ai, L.; Mueller, J. K.

10.1101/234666 — neuroscience — Posted on 2018-02-08

1284 Unsupervised clustering of temporal patterns in high-dimensional neuronal ensembles using a novel dissimilarity measure

Grossberger, L.; Battaglia, F. P.; Vinck, M.

10.1101/252791 — neuroscience — Posted on 2018-02-08

1285 Differential role of prefrontal and parietal cortices in controlling level of consciousness

Pal, D.; Dean, J.; Liu, T.; Watson, C.; Hudetz, A.; Mashour, G. A.

10.1101/262360 — neuroscience — Posted on 2018-02-08

1286 Quantifying differences between passive and task-evoked intrinsic functional connectivity in a large-scale brain simulation

Ulloa, A.; Horwitz, B.

10.1101/250894 — neuroscience — Posted on 2018-02-08

1287 Growth potential of Listeria monocytogenes in twelve different types of RTE salads: impact of food matrix, storage temperature and shelf life

Ziegler, M.; Kent, D.; Stephan, R.; Guldimann, C.

10.1101/261552 — microbiology — Posted on 2018-02-08

1288 Genotypic and phenotypic diversity within the neonatal HSV-2 population

Akhtar, L. N.; Bowen, C. D.; Renner, D. W.; Pandey, U.; Della Fera, A. N.; Kimberlin, D. W.; Prichard, M. N.; Whitley, R. J.; Weitzman, M. D.; Szpara, M. L.

10.1101/262055 — microbiology — Posted on 2018-02-08

1289 Stronger connectivity of the resident gut microbiome lends resistance to invading bacteria

Herren, C.; Baym, M.

10.1101/261750 — microbiology — Posted on 2018-02-08

1290 A T7 phage factor required for managing RpoS in Escherichia coli

Tabib-Salazar, A.; Liu, B.; Barkar, D.; Burchell, L.; Qimron, U.; Matthews, S.; Wigneshweraraj, R.

10.1101/262279 — microbiology — Posted on 2018-02-08

1291 The Autoimmune Disease Risk Allele rs6897932 Modulates Monocyte IL7R Surface and Soluble Receptor Levels in a Context-Specific Manner

10.1101/262410 — immunology — Posted on 2018-02-08

1292 A complete nanonpore-only assembly of an XDR Mycobacterium tuberculosis Beijing lineage strain identifies novel genetic variation in repetitive PE/PPE gene regions

Bainomugisa, A.; Duarte, T.; Lavu, E.; Pandey, S.; Coulter, C.; Marais, B.; Coin, L.

10.1101/256719 — genomics — Posted on 2018-02-08

1293 Genome-wide study identifies 611 loci associated with risk tolerance and risky behaviors

Karlsson Linner, R.; Biroli, P.; Kong, E.; Meddens, S. F. W.; Wedow, R.; Fontana, M. A.; Lebreton, M.; Abdellaoui, A.; Hammerschlag, A. R.; Nivard, M. G.; Okbay, A.; Rietveld, C. A.; Timshel, P. N.; Tino, S. P.; Trzaskowski, M.; de Vlaming, R.; Zünd, C. L.; Bao, Y.; Buzdugan, L.; Caplin, A. H.; Chen, C.-Y.; Eibich, P.; Fontanillas, P.; Gonzalez, J. R.; Joshi, P. K.; Karhunen, V.; Kleinman, A.; Levin, R. Z.; Lill, C. M.; Meddens, G. A.; Muntane, G.; Sanchez-Roige, S.; van Rooij, F. J.; Taskesen, E.; Wu, Y.; Zhang, F.; 23andMe Research Team, ; eQTLgen Consortium, ; International Cannab

10.1101/261081 — genetics — Posted on 2018-02-08

1294 GWAS identifies 10 loci for objectively-measured physical activity and sleep with causal roles in cardiometabolic disease.

Doherty, A.; Smith-Bryne, K.; Ferreira, T.; Holmes, M. V.; Holmes, C.; Pulit, S. L.; Lindgren, C. M.

10.1101/261719 — genetics — Posted on 2018-02-08

1295 Host range and genetic plasticity explain the co-existence of integrative and extrachromosomal mobile genetic elements

Cury, J.; Oliveira, P.; de la Cruz, F.; Rocha, E.

10.1101/250266 — evolutionary biology — Posted on 2018-02-08

1296 Molecular Clock and Phylogeny of Anopheles species of the subgenus Nyssorhynchus (Diptera: Culicidae)

Hoyos-Lopez, R.

10.1101/262147 — evolutionary biology — Posted on 2018-02-08

1297 Convergent regulatory evolution and the origin of flightlessness in palaeognathous birds

Sackton, T. B.; Grayson, P.; Cloutier, A.; Hu, Z.; Liu, J. S.; Wheeler, N. E.; Gardner, P. P.; Clarke, J. A.; Baker, A. J.; Clamp, M.; Edwards, S. V.

10.1101/262584 — evolutionary biology — Posted on 2018-02-08

1298 Environmental DNA reveals the structure of phytoplankton assemblages along a 2900-km transect in the Mississippi River

Craine, J.; Henson, M. W.; Thrash, J. C.; Hanssen, J.; Spooner, G.; Fleming, P.; Pukonen, M.; Stahr, F.; Spaulding, S.; Fierer, N.

10.1101/261727 — ecology — Posted on 2018-02-08

1299 An agent-based model of cattle grazing toxic Geyer’s larkspur

Jablonski, K.; Boone, R. B.; Meiman, P. J.

10.1101/218032 — ecology — Posted on 2018-02-08

1300 Co-entangled actin-microtubule composites exhibit tunable stiffening and power-law stress relaxation

Ricketts, S. N.; Ross, J. L.; Robertson-Anderson, R. M.

10.1101/262089 — biophysics — Posted on 2018-02-08

1301 Reconstructing complex lineage trees from scRNA-seq data using MERLoT

Parra, R. G.; Papadopoulos, N.; Ahumada-Arranz, L.; El Kholtei, J.; Treutlein, B.; Soeding, J.

10.1101/261768 — bioinformatics — Posted on 2018-02-08

1302 hts-nim: scripting high-performance genomic analyses

Pedersen, B. S.; Quinlan, A. R.

10.1101/261735 — bioinformatics — Posted on 2018-02-08

1303 Improving Metagenomic Assemblies Through Data Partitioning: a GC content approach

Miranda, F. M.; Batista, C.; Silva, A.; Morais, J.; Neto, N.; Ramos, R.

10.1101/261784 — bioinformatics — Posted on 2018-02-08

1304 Active Function Learning

Jones, A.; Schulz, E.; Meder, B.; Ruggeri, A.

10.1101/262394 — animal behavior and cognition — Posted on 2018-02-08

1305 Computational elucidation of regulatory network responding to acid stress in Lactococcus lactis MG1363

Chen, X.; Ma, A.; Zhang, H.; Liu, C.; Cao, H.; Ma, Q.

10.1101/261453 — systems biology — Posted on 2018-02-08

1306 Transcriptome and metabolome analysis provide insights into root and root released organic anion responses to phosphorus deficiency in oat

Wang, Y.; Lysoe, E.; Armarego-Marriott, T.; Erban, A.; Paruch, L.; van Eerde, A.; Bock, R.; Liu Clarke, J.

10.1101/262014 — plant biology — Posted on 2018-02-08

1307 Nuclear localization of TORC1 and cellular co-localization of TORC1 and c-Fos in the visceral neuraxis after systemic LiCl injection

Kimbrough, A.; Houpt, T. A.

10.1101/259812 — neuroscience — Posted on 2018-02-08

1308 Descriptors of Pain Quality Associate with Pulpal and Periapical Diagnostic Tests in Patients Experiencing Acute Tooth Pain

Erdogan, O.; Malek, M.; Janal, M. N.; Jennifer, G.

10.1101/262022 — neuroscience — Posted on 2018-02-08

1309 Learning multiple concurrent higher-order visual sequences in human primary visual cortex

Rosenthal, C. R.; Mallik, I.; Caballero-Gaudes, C.; Sereno, M.; Soto, D.

10.1101/261255 — neuroscience — Posted on 2018-02-08

1310 Effects of coil orientation on Motor Evoked Potentials from Orbicularis Oris and First Dorsal Interosseus

Adank, P.; Kennedy-Higgins, D.; Maegherman, G.; Hannah, R.; Nuttal, H. E.

10.1101/262261 — neuroscience — Posted on 2018-02-08

1311 Environmentally enriched pigs have transcriptional profiles consistent with neuroprotective effects and microglial depletion

Brown, S. M.; Bush, S. J.; Summers, K. M.; Hume, D. A.; Lawrence, A. B.

10.1101/262469 — molecular biology — Posted on 2018-02-08

1312 A role for tetracycline selection in the evolution of Clostridium difficile PCR-ribotype 078

Dingle, K. E.; Didelot, X.; Quan, T. P.; Eyre, D. W.; Stoesser, N.; Marwick, C. A.; Coia, J.; Brown, D.; Buchanan, S.; Ijaz, U. Z.; Goswami, C.; Douce, G.; Fawley, W. N.; Wilcox, M. H.; Peto, T. E.; Walker, A. S.; Crook, D. W.

10.1101/262352 — microbiology — Posted on 2018-02-08

1313 An Escherichia coli nitrogen starvation response is important for mutualistic coexistence with Rhodopseudomonas palustris

McCully, A. L.; Behringer, M. G.; Gliessman, J. R.; Pilipenko, E. V.; Mazny, J. L.; Lynch, M.; Drummond, D. A.; McKinlay, J. B.

10.1101/262139 — microbiology — Posted on 2018-02-08

1314 DNA methylation oscillation defines classes of enhancers

Libertini, E.; Hamoudi, R.; Heath, S.; Lancashire, L.; Garcia, A. R.; Grassi, L.; Downes, K.; Ouwehand, W.; Javierre, B.-M.; Cairns, J.; Wingett, S.; Paul, D.; Gut, M.; Gut, I.; Martens, J.; Ivliev, A.; Stunnenberg, H.; Frontini, M.; Spivakov, M.; Fraser, P.; Cutler, A.; Wallace, C.; Beck, S.

10.1101/262212 — genomics — Posted on 2018-02-08

1315 Systematic Discovery of Conservation States for Single-Nucleotide Annotation of the Human Genome

Sperlea, A. C.; Ernst, J.

10.1101/262097 — genomics — Posted on 2018-02-08

1316 Lentiviral co-packaging mitigates the effects of intermolecular recombination and multiple integrations in pooled genetic screens

Feldman, D.; Singh, A.; Garrity, A. J.; Blainey, P. C.

10.1101/262121 — genomics — Posted on 2018-02-08

1317 Generating genomic platforms to study Candida albicans pathogenesis

Legrand, M.; Bachellier-Bassi, S.; Lee, K. K.; Chaudhari, Y.; Tournu, H.; Arbogast, L.; Boyer, H.; Chauvel, M.; Cabral, V.; Maufrais, C.; Nesseir, A.; Maslanka, I.; Permal, E.; Rossignol, T.; Walker, L. A.; Zeidler, U.; Znaidi, S.; Schoeters, F.; Majgier, C.; Julien, R. A.; Ma, L.; Tichit, M.; Bouchier, C.; Van Dijck, P.; Munro, C. A.; d'Enfert, C.

10.1101/261628 — genomics — Posted on 2018-02-08

1318 AnoniMME: Bringing Anonymity to the Matchmaker Exchange Platform for Rare Disease Gene Discovery

Oprisanu, B.; De Cristofaro, E.

10.1101/262295 — genomics — Posted on 2018-02-08

1319 Mapping diversification metrics in macroecological studies: Prospects and challenges

Pinto Ledezma, J. N.; Velasco, J. A.

10.1101/261867 — ecology — Posted on 2018-02-08

1320 Evolution increases ecosystem temporal stability and recovery from a flood in grassland communities

van Moorsel, S.; Hahl, T.; Petchey, O. L.; Ebeling, A.; Eisenhauer, N.; Schmid, B.; Wagg, C.

10.1101/262337 — ecology — Posted on 2018-02-08

1321 Evidence for rapid evolution in a grassland biodiversity experiment

van Moorsel, S. J.; Schmid, M. W.; Wagemaker, C. A. M.; van Gurp, T.; Schmid, B.; Vergeer, P.

10.1101/262303 — ecology — Posted on 2018-02-08

1322 Removing Contaminants from Metagenomic Databases

Lu, J.; Salzberg, S.

10.1101/261859 — bioinformatics — Posted on 2018-02-08

1323 Regulation of Decellularized Tissue Remodeling via Scaffold-Mediated Lentiviral Delivery in Anatomically-Shaped Osteochondral Constructs

Rowland, C.; Glass, K. A.; Ettyreddy, A. R.; Gloss, C. C.; Matthews, J.; Huynh, N. P. T.; Guilak, F.

10.1101/261792 — bioengineering — Posted on 2018-02-08

1324 Viral-mediated optical stimulation of peripheral motor nerves in non-human primates

Williams, J.; Vazquez, A. L.; Schwartz, A. B.

10.1101/261925 — bioengineering — Posted on 2018-02-08

1325 Contribution of the axon initial segment to action potentials recorded extracellularly

Telenczuk, M.; Brette, R.; Destexhe, A.; Telenczuk, B.

10.1101/243808 — neuroscience — Posted on 2018-02-08

1326 Identification of loci where DNA methylation potentially mediates genetic risk of type 1 diabetes

Ye, J.; Richardson, T. G.; McArdle, W.; Relton, C.; Gillespie, K. M.; Suderman, M.; Hemani, G.

10.1101/248260 — genomics — Posted on 2018-02-08

1327 Pathways-wide genetic risks in Chlamydial infections overlap between tissue tropisms: A genome-wide association scan

Roberts, C. h.; Ouberg, S.; Preston, M. D.; de Vries, H. J. C.; Holland, M. J.; Morre, S. A.

10.1101/205286 — genetics — Posted on 2018-02-08

1328 Linear relationship between peak and season-long abundances in insects

Onufrieva, K. S.; Onufriev, A. V.

10.1101/172270 — ecology — Posted on 2018-02-08

1329 Peptide Pattern Recognition for high-throughput protein sequence analysis and clustering

Busk, P. K.

10.1101/181917 — bioinformatics — Posted on 2018-02-08

1330 Molecular basis for the maintenance of lipid asymmetry in the outer membrane of Escherichia coli

Yeow, J.; Tan, K. W.; Holdbrook, D. A.; Chong, Z.-S.; Marzinek, J. K.; Bond, P. J.; Chng, S. S.

10.1101/192500 — biochemistry — Posted on 2018-02-08

1331 ssbio: A Python Framework for Structural Systems Biology

Mih, N.; Brunk, E.; Chen, K.; Catoiu, E.; Sastry, A.; Kavvas, E.; Monk, J. M.; Zhang, Z.; Palsson, B. O.

10.1101/165506 — systems biology — Posted on 2018-02-08

1332 Neuronal origin of the temporal dynamics of spontaneous BOLD activity correlation

Matsui, T.; Murakami, T.; Ohki, K.

10.1101/169698 — neuroscience — Posted on 2018-02-08

1333 A robust method to estimate regional polygenic correlation identifies heterogeneity in the shared heritability between complex traits

Pare, G.; Mao, S.; Deng, W. Q.

10.1101/143644 — genetics — Posted on 2018-02-08

1334 Radical mutations persist longer in the absence of sex

Sharbrough, J.; Luse, M.; Boore, J. L.; Logsdon, J. M.; Neiman, M.

10.1101/049924 — evolutionary biology — Posted on 2018-02-08

1335 Absence of the Spindle Assembly Checkpoint restores mitotic fidelity upon loss of sister chromatid cohesion

Silva, R. D.; Mirkovic, M.; Guilgur, L. G.; Rathore, O. S.; Martinho, R. G.; Oliveira, R. A.

10.1101/262204 — cell biology — Posted on 2018-02-08

1336 Regulation of ATM and ATR by SMARCAL1 and BRG1

Sethy, R.; Rakesh, R.; Patne, K.; Arya, V.; Sharma, T.; Haokip, D.; Kumari, R.; Muthuswami, R.

10.1101/261610 — molecular biology — Posted on 2018-02-08

1337 IFIT3 and IFIT2/3 promote IFIT1-mediated translation inhibition by enhancing binding to non-self RNA.

Fleith, R. C.; Mears, H. V.; Emmott, E.; Graham, S. C.; Mansur, D. S.; Sweeney, T. R.

10.1101/261776 — immunology — Posted on 2018-02-08

1338 Phylodynamic assessment of intervention strategies for the West African Ebola virus outbreak

Dellicour, S.; Baele, G.; Dudas, G.; Faria, N. R.; Pybus, O. G.; Suchard, M. A.; Rambaut, A.; Lemey, P.

10.1101/163691 — epidemiology — Posted on 2018-02-08

1339 Whole genome analysis illustrates global clonal population structure of the ubiquitous dermatophyte pathogen Trichophyton rubrum

Persinoti, G. F.; Martinez, D. A.; Li, W.; Dogen, A.; Billmyre, R. B.; Averette, A.; Goldberg, J. M.; Shea, T.; Young, S.; Zeng, Q.; Oliver, B.; Barton, R.; Metin, B.; Hilmioglu-Polat, S.; Ilkit, M.; Gräser, Y.; Martinez-Rossi, N.; White, T. C.; Heitman, J.; Cuomo, C. A.

10.1101/261743 — genetics — Posted on 2018-02-08

1340 GPseudoRank: a permutation sampler for single cell orderings

Strauss, M. E.; Reid, J. E.; Wernisch, L.

10.1101/211417 — bioinformatics — Posted on 2018-02-08

1341 Co-entangled actin-microtubule composites exhibit tunable stiffening and power-law stress relaxation

Ricketts, S. N.; Ross, J. L.; Roberston-Anderson, R. M.

10.1101/262089 — biophysics — Posted on 2018-02-07

1342 Reversing Glial Scar Back To Neural Tissue Through NeuroD1-Mediated Astrocyte-To-Neuron Conversion

Zhang, L.; Lei, Z.; Guo, Z.; Pei, Z.; Chen, Y.; Zhang, F.; Cai, A.; Mok, Y. K.; Lee, G.; Swaminathan, V.; Wang, F.; Bai, Y.; Chen, G.

10.1101/261438 — neuroscience — Posted on 2018-02-07

1343 Dual signaling of Wamide myoinhibitory peptides through a peptide-gated channel and a GPCR in Platynereis

Schmidt, A.; Bauknecht, P.; Williams, E. A.; Augustinowski, K.; Grunder, S.; Jekely, G.

10.1101/261990 — neuroscience — Posted on 2018-02-07

1344 Cell type-specific variation of somatotopic precision across corticostriatal projections

Hooks, B. M.; Papale, A. E.; Paletzki, R.; Feroze, M.; Eastwood, B. S.; Couey, J. J.; Winnubst, J.; Chandrashekar, J.; Gerfen, C. R.

10.1101/261446 — neuroscience — Posted on 2018-02-07

1345 Identification of piRNA binding sites reveals the Argonaute regulatory landscape of the C. elegans germline

Shen, E.-Z.; Chen, H.; Ozturk, A. R.; Tu, S.; Shirayama, M.; Tang, W.; Ding, Y.-H.; Dai, S.-Y.; Weng, Z.; Mello, C. C.

10.1101/262113 — genetics — Posted on 2018-02-07

1346 Speed Regulation and Gradual Enhancer Switching Models as Flexible and Evolvable Patterning Mechanisms

Kuhlmann, L.; El-Sherif, E.

10.1101/261891 — developmental biology — Posted on 2018-02-07

1347 FGF activity asymmetrically regulates the timing of habenular neurogenesis in a Nodal-dependent manner

Dean, B. J.; Gamse, J. T.; Wu, S.-Y.

10.1101/261834 — developmental biology — Posted on 2018-02-07

1348 ATP-dependent force generation and membrane scission by ESCRT-III and Vps4

Schoeneberg, J.; Yan, S.; Righini, M.; Remec Pavlin, M.; Lee, I.-H.; Carlson, L.-A.; Bahrami, A. H.; Goldman, D. H.; Ren, X.; Hummer, G.; Bustamante, C.; Hurley, J.

10.1101/262170 — biophysics — Posted on 2018-02-07

1349 Influenza A Virus Negative Strand RNA is Translated for CD8+ T Cell Immunosurveillance

Hickman, H.; Mays, J.; Gibbs, J.; Kosik, I.; Magadan, J.; Takeda, K.; Das, S.; Reynoso, G.; Ngudiankama, B.; Wei, J.; Shannon, J.; McManus, D.; Yewdell, J.

10.1101/261966 — immunology — Posted on 2018-02-07

1350 Realizing ‘integral control’ in living cells: How to overcome leaky integration due to dilution?

Qian, Y.; Del Vecchio, D.

10.1101/141051 — synthetic biology — Posted on 2018-02-07

1351 Conceptual content in images triggers rapid shifts of covert attention

Wyble, B.; Hess, M.; Callahan-Flintoft, C.; Folk, C.

10.1101/259929 — neuroscience — Posted on 2018-02-07

1352 Within-patient HIV mutation frequencies reveal fitness costs of CpG dinucleotides, drastic amino acid changes and G->A mutations

Theys, K.; Feder, A.; Gelbart, M.; Hartl, M.; Stern, A.; Pennings, P. S.

10.1101/057026 — evolutionary biology — Posted on 2018-02-07

1353 Estimates of Introgression as a Function of Pairwise Distances

Pfeifer, B.; Kapan, D. D.

10.1101/154377 — evolutionary biology — Posted on 2018-02-07

1354 Genomic imprinting mediates dosage compensation in a young plant XY system

Muyle, A.; Zemp, N.; Fruchard, C.; Cegan, R.; Vrana, J.; Deschamps, C.; Tavares, R.; Picard, F.; Hobza, R.; Widmer, A.; Marais, G.

10.1101/179044 — evolutionary biology — Posted on 2018-02-07

1355 A nonlinear updating algorithm captures suboptimal inference in the presence of signal-dependent noise

Egger, S. W.; Jazayeri, M.

10.1101/258434 — neuroscience — Posted on 2018-02-07

1356 Inferring mechanistic models of neuronal microcircuits from single-trial spike trains

Ladenbauer, J.; Ostojic, S.

10.1101/261016 — neuroscience — Posted on 2018-02-07

1357 Allele frequency-free inference of close familial relationships from genotypes or low depth sequencing data

Waples, R. K.; Albrechtsen, A.; Moltke, I.

10.1101/260497 — genetics — Posted on 2018-02-07

1358 Predictors of emergency department attendance following NHS 111 calls for children and young people: analysis of linked data

Wolters, A.; Robinson, C.; Hargreaves, D.; Pope, R.; Maconochie, I.; Deeny, S. R.; Steventon, A.

10.1101/237750 — epidemiology — Posted on 2018-02-07

1359 Lineage tracing axial progenitors using Nkx1.2CreERT2 mice defines their trunk and tail contributions

Rodrigo Albors, A.; Halley, P. A.; Storey, K. G.

10.1101/261883 — developmental biology — Posted on 2018-02-07

1360 Genetic determinants of co-accessible chromatin regions in T cell activation across humans

Gate, R. E.; Cheng, C. S.; Aiden, A. P.; Siba, A.; Tabaka, M.; Lituiev, D.; Machol, I.; Gordon, M. G.; Subramaniam, M.; Shammim, M.; Hougen, K. L.; Wortman, I.; Huang, S.-C.; Durand, N. C.; Feng, T.; De Jager, P. L.; Chang, H. Y.; Lieberman Aiden, E.; Benoist, C.; Beer, M. A.; Ye, C. J.; Regev, A.

10.1101/090241 — genomics — Posted on 2018-02-07

1361 From preliminary to definitive plans: two classes of neurons in frontal eye field

Glaser, J. I.; Wood, D. K.; Lawlor, P. N.; Segraves, M. A.; Kording, K. P.

10.1101/251835 — neuroscience — Posted on 2018-02-07

1362 Spatial reconstruction of single enterocytes uncovers broad zonation along the intestinal villus axis

Moor, A. E.; Harnik, Y.; Ben-Moshe, S.; Massasa, E. E.; Bahar Halpern, K.; Itzkovitz, S.

10.1101/261529 — systems biology — Posted on 2018-02-07

1363 Regulation by competition: a hidden layer of gene regulatory network

Yuan, Y.; Wei, L.; Hu, T.; Li, S.; Cheng, T.; Lei, J.; Xie, Z.; Zhang, M. Q.; Wang, X.

10.1101/258129 — systems biology — Posted on 2018-02-07

1364 Hair cells with heterogeneous transfer characteristics encode mechanical stimuli in the lateral line of zebrafish

Pichler, P.; Lagnado, L.

10.1101/261669 — neuroscience — Posted on 2018-02-07

1365 Imposing a curfew on the use of screen electronic devices improves sleep and daytime vigilance in adolescents.

Perrault, A. A.; Bayer, L.; Peuvrier, M.; Afyouni, A.; Ghisletta, P.; Perrig, S.; Schwartz, S.; Sterpenich, V.

10.1101/259309 — neuroscience — Posted on 2018-02-07

1366 Choice history biases subsequent evidence accumulation

Urai, A. E.; de Gee, J. W.; Donner, T. H.

10.1101/251595 — neuroscience — Posted on 2018-02-07

1367 Microbiome-host systems interactions: Protective effects of propionate upon the blood-brain barrier

Hoyles, L.; Snelling, T.; Umlai, U.-K.; Nicholson, J. K.; Carding, S. R.; Glen, R. C.; McArthur, S.

10.1101/170548 — neuroscience — Posted on 2018-02-07

1368 An annual cycle of gene regulation in the red-legged salamander mental gland: from hypertrophy to expression of rapidly evolving pheromones

Wilburn, D. B.; Feldhoff, R. C.

10.1101/261495 — molecular biology — Posted on 2018-02-07

1369 Chromosome-scale comparative sequence analysis unravels molecular mechanisms of genome evolution between two wheat cultivars

Thind, A. K.; Wicker, T.; Mueller, T.; Ackermann, P. M.; Steuernagel, B.; Wulff, B. B. H.; Spannagl, M.; Twardziok, S. O.; Felder, M.; Lux, T.; Mayer, K. F. X.; International Wheat Genome Sequencing Consortium, ; Keller, B.; Krattinger, S. G.

10.1101/260406 — genomics — Posted on 2018-02-07

1370 A database of simulated tumor genomes towards accurate detection of somatic small variants in cancer

Meng, J.; Chen, Y.-P. P.

10.1101/261503 — bioinformatics — Posted on 2018-02-07

1371 Mutation in DsbA signal sequence hampers the SRP mechanism: A new strategy to combat virulence factor

Durrani, F. G.; Gul, R.; Mirza, M. U.; Kaderbhai, N. N.; Saleem, M.; Akhter, M. W.

10.1101/261537 — bioengineering — Posted on 2018-02-07

1372 Identification and characterization of moonlighting long non-coding RNAs based on RNA and protein interactome

Cheng, L.; Leung, K.-S.

10.1101/261511 — systems biology — Posted on 2018-02-07

1373 The use of a chimeric rhodopsin vector for the detection of new proteorhodopsins based on color

Pushkarev, A.; Hevroni, G.; Roitman, S.; Shim, J.-g.; Choi, A.; Jung, K.-H.; Beja, O.

10.1101/162016 — microbiology — Posted on 2018-02-07

1374 Analysis of Spounaviruses as a Case Study for the Overdue Reclassification of Tailed Bacteriophages

Barylski, J.; Enault, F.; Dutilh, B. E.; Schuller, M. B.; Edwards, R. A.; Gillis, A.; Klumpp, J.; Knezevic, P.; Krupovic, M.; Kuhn, J. H.; Lavigne, R.; Oksanen, H. M.; Sullivan, M. B.; Wittmann, J.; Tolstoy, I.; Brister, J. R.; Kropinski, A. M.; Adriaenssens, E. M.

10.1101/220434 — microbiology — Posted on 2018-02-07

1375 DPP9 is an endogenous and direct inhibitor of the NLRP1 inflammasome that guards against human auto-inflammatory diseases

Zhong, F. L.; Robinson, K.; Lim, C.; Harapas, C. R.; Yu, C.-H.; Xie, W.; Sobota, R. M.; Au, V. B.; Hopkins, R.; Connolly, J. E.; Masters, S.; Reversade, B.

10.1101/260919 — immunology — Posted on 2018-02-07

1376 Noise-driven Cell Differentiation and the Emergence of Organization

Safdari, H.; Kalirad, A.; Picioreanu, C.; Tusserkani, R.; Goliaei, B.; Sadeghi, M.

10.1101/220525 — developmental biology — Posted on 2018-02-07

1377 Myosin Heavy Chain-embryonic is a crucial regulator of skeletal muscle development and differentiation.

Sharma, A.; Agarwal, M.; Kumar, A.; Kumar, P.; Saini, M.; Kardon, G.; Mathew, S.

10.1101/261685 — developmental biology — Posted on 2018-02-07

1378 Capitalizing on Competition: An Evolutionary Model of Competitive Release in Metastatic Castration Resistant Prostate Cancer Treatment

West, J.; Ma, Y.; Newton, P. K.

10.1101/190140 — cancer biology — Posted on 2018-02-07

1379 Recapitulation of human germline coding variation in an ultra-mutated infant leukemia

Gout, A. M.; Kotecha, R. S.; Kaur, P.; Abad, A.; Foley, B.; Carter, K. W.; Cole, C. H.; Bond, C. S.; Kees, U. R.; Waithman, J.; Cruickshank, M. N.

10.1101/248690 — cancer biology — Posted on 2018-02-07

1380 Structural-Kinetic-Thermodynamic Relationships Identified from Physics-based Molecular Simulation Models

Rudzinski, J. F.; Bereau, T.

10.1101/183053 — biophysics — Posted on 2018-02-07

1381 The harmonic mean p-value for combining dependent tests

Wilson, D. J.

10.1101/171751 — bioinformatics — Posted on 2018-02-07

1382 Simultaneous Determination of Protein Structure and Dynamics Using Cryo-Electron Microscopy

Bonomi, M.; Pellarin, R.; Vendruscolo, M.

10.1101/219972 — bioinformatics — Posted on 2018-02-07

1383 Sharq, a versatile preprocessing and QC pipeline for Single Cell RNA-seq

Candelli, T.; Lijnzaad, P.; Muraro, M. J.; Kerstens, H.; Kemmeren, P.; van Oudenaarden, A.; Margaritis, T.; Holstege, F.

10.1101/250811 — bioinformatics — Posted on 2018-02-07

1384 NormExpression: an R package to normalize gene expression data using evaluated methods

Wu, Z.; Liu, W.; Ji, H.; Yu, D.; Wang, H.; Liu, L.; Ji, S.; Shan, G.

10.1101/251140 — bioinformatics — Posted on 2018-02-07

1385 Choice of PP1 catalytic subunit affects neither requirement for G-actin nor insensitivity to Sephin1 of PPP1R15A-regulated eIF2αP dephosphorylation

Crespillo-Casado, A.; Claes, Z.; Choy, M. S.; Peti, W.; Bollen, M.; Ron, D.

10.1101/228809 — biochemistry — Posted on 2018-02-07

1386 Regulation of chloroplast NADH dehydrogenase-like complex by NADPH-dependent thioredoxin system

Nikkanen, L.; Toivola, J.; Trotta, A.; Guinea Diaz, M.; Tikkanen, M.; Aro, E.-M.; Rintamaki, E.

10.1101/261560 — plant biology — Posted on 2018-02-07

1387 A proteolytic complex targets multiple cell wall hydrolases in Pseudomonas aeruginosa

Srivastava, D.; Seo, J.; Rimal, B.; Kim, S. J.; Darwin, A. J.

10.1101/260620 — microbiology — Posted on 2018-02-07

1388 In situ relationships between microbiota and potential pathobiota in Arabidopsis thaliana

Bartoli, C.; Frachon, L.; Barret, M.; Rigal, M.; Huard-Chauveau, C.; Mayjonade, B.; Zanchetta, C.; Bouchez, O.; Roby, D.; Carrere, S.; Roux, F.

10.1101/261602 — microbiology — Posted on 2018-02-07

1389 Motor-Like Properties of Non-Motor Enzymes

Slochower, D. R.; Gilson, M. K.

10.1101/121848 — biophysics — Posted on 2018-02-07

1390 Silencing of a unique integrated domain nucleotide-binding leucine-rich repeat gene in wheat abolishes Diuraphis noxia resistance

Nicolis, V. F.; Venter, E.

10.1101/261644 — plant biology — Posted on 2018-02-07

1391 Single-trial Phase Entrainment of Theta Oscillations in Sensory Regions Predicts Human Associative Memory Performance

Wang, D.; Clouter, A.; Chen, Q.; Shapiro, K. L.; Hanslmayr, S.

10.1101/261487 — neuroscience — Posted on 2018-02-07

1392 The subesophageal ganglion modulates locust inter-leg sensory-motor interactions via contralateral pathways

Knebel, D.; Woerner, J.; Rillich, J.; Nadler, L.; Ayali, A.; Couzin-Fuchs, E.

10.1101/261164 — neuroscience — Posted on 2018-02-07

1393 Extinction recall of fear memories formed before stress is not affected despite amygdalar hyperactivity

Chattarji, S.; Rahman, M. M.; Shukla, A.

10.1101/261578 — neuroscience — Posted on 2018-02-07

1394 PIWI Proteins Act at Multiple Steps in the Production of Their Own Guides

Zamore, P.; Gainetdinov, I.; Coplan, C.; Cecchini, K.

10.1101/261545 — molecular biology — Posted on 2018-02-07

1395 A conserved regulatory program drives emergence of the lateral plate mesoderm

Hess, C.; Prummel, K. D.; Nieuwenhuize, S.; Parker, H.; Rogers, K. W.; Kozmikova, I.; Racioppi, C.; Burger, S.; Brombacher, E. C.; Burger, A.; Felker, A.; Chiavacci, E.; Shah, G.; Huisken, J.; Kozmik, Z.; Christiaen, L.; Mueller, P.; Bronner, M.; Krumlauf, R.; Mosimann, C.

10.1101/261115 — developmental biology — Posted on 2018-02-07

1396 High-quality ultrastructural preservation using cryofixation for 3D electron microscopy of genetically labeled tissues

Tsang, T. K.; Bushong, E. A.; Boassa, D.; Hu, J.; Romoli, B.; Phan, S.; Dulcis, D.; Su, C.-Y.; Ellisman, M. H.

10.1101/261594 — biophysics — Posted on 2018-02-07

1397 A Chemical Biology Toolbox for the Study of Protein Methyltransferases and Epigenetic Signaling

Scheer, S.; Ackloo, S.; Medina, T. S.; Schapira, M.; Li, F.; Ward, J. A.; Lewis, A. M.; Northrop, J. P.; Richardson, P. L.; Kaniskan, H. U.; Shen, Y.; Liu, J.; Smil, D.; Luo, M.; Jin, J.; Barsyte-Lovejoy, D.; Huber, K. V. M.; De Carvalho, D. D.; Vedadi, M.; Zaph, C.; Brown, P. J.; Arrowsmith, C. H.

10.1101/260638 — biochemistry — Posted on 2018-02-07

1398 Neural signatures of the processing of temporal patterns in sounds

Herrmann, B.; Johnsrude, I. S.

10.1101/261271 — neuroscience — Posted on 2018-02-07

1399 Emergence of Human Amygdala Functional Networks: 3 Months to 5 Years of Age

Gabard-Durnam, L. J.; O'Muircheartaigh, J.; Dirks, H.; Dean, D.; Tottenham, N.; Deoni, S.

10.1101/261347 — neuroscience — Posted on 2018-02-07

1400 Concentration of 2’C-methyladenosine triphosphate by Leishmania guyanensis enables specific inhibition of Leishmania RNA virus 1 via its RNA polymerase

Robinson, J. I.; Beverley, S. M.

10.1101/261172 — microbiology — Posted on 2018-02-07

1401 Multiplexed enrichment and genomic profiling of peripheral immune cell subsets on a microfluidic chip

Reyes, M.; Vickers, D.; Billman, K.; Eisenhaure, T.; Hoover, P.; Browne, E.; Rao, D. A.; Hacohen, N.; Blainey, P. C.

10.1101/261321 — bioengineering — Posted on 2018-02-07

1402 A novel surfactant protein is associated with extrapulmonary respiration in lungless salamanders

Lewis, Z. R.; Dorantes, J. A.; Hanken, J.

10.1101/261412 — zoology — Posted on 2018-02-07

1403 Proteomic analysis of chemosensory organs in the honey bee parasite Varroa destructor: a comprehensive examination of the potential carriers for semiochemicals

Iovinella, I.; McAfee, A.; Mastrobuoni, G.; Kempa, S.; Foster, L. J.; Pelosi, P.; Dani, F. R.

10.1101/260539 — zoology — Posted on 2018-02-07

1404 NeoDTI: Neural integration of neighborinformation from a heterogeneous network fordiscovering new drug-target interactions

Wan, F.; Hong, L.; Xiao, A.; Jiang, T.; Zeng, J.

10.1101/261396 — systems biology — Posted on 2018-02-07

1405 Mammalian Cells Engineered to Produce Novel Steroids

Spady, E. S.; Wyche, T. P.; Rollins, N. J.; Clardy, J.; Way, J. C.; Silver, P. A.

10.1101/261362 — synthetic biology — Posted on 2018-02-07

1406 Non-invasive Assessment of Liver Disease in Rats Using Multiparametric Magnetic Resonance Imaging: A Feasibility Study

Hoy, A. M.; McDonald, N.; Lennen, R. J.; Milanesi, M.; Herlihy, A. H.; Kendall, T. J.; Mungall, W.; Gyngell, M.; Banerjee, R.; Janiczek, R. L.; Murphy, P. S.; Jansen, M. A.; Fallowfield, J. A.

10.1101/261032 — pathology — Posted on 2018-02-07

1407 Non-Canonical Activation of CREB Mediates Neuroprotection in a C. elegans Model of Excitotoxic Necrosis

Feldmann, K. G.; Chowdhury, A.; Becker, J.; McAlpin, N.; Ahmed, T.; Haider, S.; Xia, J. X. R.; Diaz, K.; Mehta, M. G.; Mano, I.

10.1101/261420 — neuroscience — Posted on 2018-02-07

1408 Flexible sensorimotor computations through rapid reconfiguration of cortical dynamics

Remington, E. D.; Narain, D.; Hosseini, E.; Jazayeri, M.

10.1101/261214 — neuroscience — Posted on 2018-02-07

1409 A Kirchhoff-Nernst-Planck framework for modeling large scale extracellular electrodiffusion surrounding morphologically detailed neurons

Solbra, A.; Bergersen, A. W.; van den Brink, J.; Malthe-Sorenssen, A.; Einevoll, G. T.; Halnes, G.

10.1101/261107 — neuroscience — Posted on 2018-02-07

1410 Perceptual insensitivity to higher-order statistical moments of coherent random dot motion

Waskom, M. L.; Asfour, J. W.; Kiani, R.

10.1101/261370 — neuroscience — Posted on 2018-02-07

1411 Prediction of the secundary structure at the tRNASer (UCN) of Lutzomyia longipalpis (Diptera: Psychodidae)

Hoyos-Lopez, R.

10.1101/261297 — molecular biology — Posted on 2018-02-07

1412 Liquid co-substrates repower sewage microbiomes

Hardegen, J.; Latorre-Perez, A.; Vilanova, C.; Gunther, T.; Simeonov, C.; Porcar, M.; Luschnig, O.; Abendroth, C.

10.1101/261339 — microbiology — Posted on 2018-02-07

1413 Optimizing Trait Predictability in Hybrid Rice Using Superior Prediction Models and Selective Omic Datasets

Wang, S.; Wei, J.; Li, R.; Qu, H.; Xie, W.; Jia, Z.

10.1101/261263 — genetics — Posted on 2018-02-07

1414 Inference of population structure from ancient DNA

Joseph, T. A.; Pe'er, I.

10.1101/261131 — evolutionary biology — Posted on 2018-02-07

1415 Evolutionary pathways for the generation of new self-incompatibility haplotypes in a non-self recognition system

Bodova, K.; Priklopil, T.; Field, D. L.; Barton, N. H.; Pickup, M.

10.1101/260414 — evolutionary biology — Posted on 2018-02-07

1416 Adaptation to sub-optimal hosts is a driver of viral diversification in the ocean

Enav, H.; Kirzner, S.; Lindell, D.; Mandel-Gutfreund, Y.; Beja, O.

10.1101/261479 — evolutionary biology — Posted on 2018-02-07

1417 Identifying Critical Points of Trajectories of Depressive Symptoms From Childhood to Young Adulthood: Evidence of Sex Differences from the Avon Longitudinal Study of Parents and Children (ALSPAC)

Kwong, A. S. F.; Manley, D.; Timpson, N. J.; Person, R. M.; Heron, J.; Sallis, H. M.; Stergiakouli, E.; Davis, O. S. P.; Leckie, G.

10.1101/193680 — epidemiology — Posted on 2018-02-07

1418 A systematic review of Hepatitis B virus (HBV) drug and vaccine escape mutations in Africa: a call for urgent action

Mokaya, J.; McNaughton, A. L.; Hadley, M.; Beloukas, A.; Geretti, A.-M.; Goedhals, D.; Matthews, P. C.

10.1101/258350 — epidemiology — Posted on 2018-02-07

1419 Using movement data to estimate contact rates in a simulated environmentally-transmitted disease system

Dougherty, E. R.; Seidel, D. P.; Carlson, C. J.; Getz, W. M.

10.1101/261198 — ecology — Posted on 2018-02-07

1420 DROSHA associates to DNA damage sites and is required for DNA repair

Cabrini, M.; Roncador, M.; Galbiati, A.; Cipolla, L.; Iannelli, F.; Sabbioneda, S.; d'Adda di Fagagna, F.; Francia, S.

10.1101/261289 — cell biology — Posted on 2018-02-07

1421 Inducible expression of immediate early genes is regulated through dynamic chromatin association by NF45/ILF2 and NF90/ILF3

Wu, T.-H.; Shi, L.; Lowe, A. W.; Nicolls, M. R.; Kao, P. N.

10.1101/261305 — cell biology — Posted on 2018-02-07

1422 Generation of pulmonary neuro-endocrine cells and tumors resembling small cell lung cancers from human embryonic stem cells

Chen, J.; Poran, A.; Unni, A.; Huang, S.; Elemento, O.; Snoeck, H.-W.; Varmus, H.

10.1101/261461 — cancer biology — Posted on 2018-02-07

1423 Integrating Hi-C links with assembly graphs for chromosome-scale assembly

Ghurye, J.; Rhie, A.; Walenz, B. P.; Schmitt, A.; Selvaraj, S.; Pop, M.; Phillippy, A. M.; Koren, S.

10.1101/261149 — bioinformatics — Posted on 2018-02-07

1424 Mitigating the lack of knowledge about long noncoding RNA: extracting biological functions

Adam, Y. A. I.; Ruiz, E. E. S.; Macedo, A. A.

10.1101/258343 — bioinformatics — Posted on 2018-02-07

1425 ChIP-BIT2: a software tool to detect weak binding events using a Bayesian integration approach

Chen, X.; Shi, X.; Hilakivi-Clarke, L.; Clarke, R.; Wang, T.-L.; Xuan, J.

10.1101/260869 — bioinformatics — Posted on 2018-02-07

1426 psichomics: graphical application for alternative splicing quantification and analysis

Saraiva-Agostinho, N.; Barbosa-Morais, N. L.

10.1101/261180 — bioinformatics — Posted on 2018-02-07

1427 ClusterPicker-II: Massively scalable transmission clustering using phylogenetic trees

Moshiri, A. N.

10.1101/261354 — bioinformatics — Posted on 2018-02-07

1428 The formation of chromatin domains: a new model

Bernardi, G.

10.1101/260323 — genomics — Posted on 2018-02-07

1429 Focal adhesion kinase regulates early steps of myofibrillogenesis in cardiomyocytes

Taneja, N.; Neininger, A. C.; Bersi, M. R.; Merryman, W. D.; Burnette, D. T.

10.1101/261248 — cell biology — Posted on 2018-02-07

1430 ASGAL: Aligning RNA-Seq Data to a Splicing Graph to Detect Novel Alternative Splicing Events

Denti, L.; Rizzi, R.; Beretta, S.; Della Vedova, G.; Previtali, M.; Bonizzoni, P.

10.1101/260372 — bioinformatics — Posted on 2018-02-07

1431 Additional Essential Oils with High Activity against Stationary Phase Borrelia burgdorferi

Feng, J.; Shi, W.; Miklossy, J.; Zhang, Y.

10.1101/260091 — microbiology — Posted on 2018-02-06

1432 No Evidence for Systematic White Matter Correlates of Dyslexia and Dyscalculia

Moreau, D.; Wilson, A. J.; McKay, N. S.; Nihill, K.; Waldie, K. E.

10.1101/259788 — neuroscience — Posted on 2018-02-06

1433 Robustness of STDP to spike timing jitter

Cui, Y.; Prokin, I.; Mendes, A.; Berry, H.; Venance, L.

10.1101/259648 — neuroscience — Posted on 2018-02-06

1434 Transcranial direct current stimulation over left inferior frontal cortex improves speech fluency in adults who stutter

Chesters, J.; Mottonen, R.; Watkins, K. E.

10.1101/259796 — neuroscience — Posted on 2018-02-06

1435 Baldspot/ELOVL6 is a conserved modifier of disease and the ER stress response

Palu, R.; Chow, C. Y.

10.1101/261206 — genetics — Posted on 2018-02-06

1436 The Effects of Normalization, Transformation, and Rarefaction on Clustering of OTU Abundance

Molik, D.; Pfrender, M.; Emrich, S.

10.1101/259325 — ecology — Posted on 2018-02-06

1437 Standardized Informatics Computing Platform for Advancing Biomedical Discovery Through Data Sharing

Navale, V.; Ji, M.; McCreedy, E.; Gebremichael, T.; Garcia, A.; Misquitta, L.; Lin, C.-H.; Fann, Y.; McAuliffe, M.

10.1101/259465 — bioinformatics — Posted on 2018-02-06

1438 LonGP: an additive Gaussian process regression model for longitudinal study designs

Cheng, L.; Ramchandran, S.; Vatanen, T.; Lietzen, N.; Lahesmaa, R.; Vehtari, A.; Lahdesmäki, H.

10.1101/259564 — bioinformatics — Posted on 2018-02-06

1439 Myoelectric Prosthesis Control: Improving Internal Model Strength and Performance Using Augmented Feedback

Shehata, A. W.; Scheme, E. J.; Sensinger, J. W.

10.1101/259754 — bioengineering — Posted on 2018-02-06

1440 Phosphorothioate-modified DNA oligonucleotides inactivate CRISPR-Cpf1 mediated genome editing

Li, B.; Zeng, C.; Li, W.; Zhang, X.; Luo, X.; Zhao, W.; Zhang, C.; Dong, Y.

10.1101/253757 — bioengineering — Posted on 2018-02-06

1441 Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: meta-analysis of data from genome-wide association studies

Fabbri, C.; Tansey, K. E.; Perlis, R. H.; Hauser, J.; Henigsberg, N.; Maier, W.; Mors, O.; Placentino, A.; Rietschel, M.; Souery, D.; Breen, G.; Curtis, C.; Lee, S. H.; Newhouse, S.; Patel, H.; O'Donovan, M.; Lewis, G.; Jenkins, G.; Weinshilboum, R. M.; Farmer, A.; Aitchison, K. J.; Craig, I.; McGuffin, P.; Schruers, K.; Biernacka, J. M.; Uher, R.; Lewis, C. M.

10.1101/259838 — genetics — Posted on 2018-02-06

1442 Avian thermoregulation in the heat: phylogenetic variation among avian orders in evaporative cooling capacity and heat tolerance

Smit, B.; Whitfield, M. C.; Talbot, W. A.; Gerson, A. R.; McKechnie, A. E.; Wolf, B. O.

10.1101/211730 — zoology — Posted on 2018-02-06

1443 Distractor inhibition contributes to retroactive attentional orienting within working memory: Evidence by lateralized alpha oscillations in the EEG

Schneider, D.; Barth, A.; Haase, H.; Hickey, C.; Wascher, E.

10.1101/235069 — neuroscience — Posted on 2018-02-06

1444 Selective increases in inter-individual variability in response to environmental enrichment

Korholz, J.; Zocher, S.; Grzyb, A. N.; Morisse, B.; Poetzsch, A.; Ehret, F.; Schmied, C.; Kempermann, G.

10.1101/260455 — neuroscience — Posted on 2018-02-06

1445 Marine cyanolichens from different littoral zones are associated with distinct bacterial communities

West, N. J.; Parrot, D.; Fayet, C.; Grube, M.; Tomasi, S.; Suzuki, M. T.

10.1101/209320 — ecology — Posted on 2018-02-06

1446 High carnivore population density highlights the conservation value of industrialised sites

Loock, D. J. E.; Williams, S. T.; Emslie, K. W.; Matthews, W. S.; Swanepoel, L. H.

10.1101/260729 — ecology — Posted on 2018-02-06

1447 TMEM16F activation by Ca2+ triggers plasmalemma expansion and directs PD-1 trafficking

Bricogne, C.; Fine, M.; Pereira, P. M.; Wang, Y.; Sung, J.; Tijani, M.; Henriques, R.; Collins, M. K.; Hilgemann, D.

10.1101/249227 — cell biology — Posted on 2018-02-06

1448 Natural Gaze Data Driven Wheelchair

Raymond, L.-A.; Piccini, M.; Subramanian, M.; Orlov, P.; Zito, G.; Faisal, A.

10.1101/252684 — bioengineering — Posted on 2018-02-06

1449 Blind prediction of noncanonical RNA structure at atomic accuracy

Watkins, A. M.; Geniesse, C.; Kladwang, W.; Zakrevsky, P.; Jaeger, L.; Das, R.

10.1101/223305 — biochemistry — Posted on 2018-02-06

1450 Alpha Oscillations Prior to Encoding Preferentially Modulate Memory Consolidation during Wake Relative to Sleep

Cross, Z. R.; Santamaria, A.; Corcoran, A. W.; Alday, P. M.; Coussens, S.; Kohler, M. J.

10.1101/202176 — neuroscience — Posted on 2018-02-06

1451 The cohesin ring uses its hinge to organize DNA using non-topological as well as topological mechanisms

Srinivasan, M.; Scheinost, J.; Petela, N.; Gligoris, T.; Wissler, M.; Ogushi, S.; Collier, J.; Voulgaris, M.; Kurze, A.; Chan, K.-L.; Hu, B.; Costanzo, V.; Nasmyth, K.

10.1101/197848 — molecular biology — Posted on 2018-02-06

1452 The impact of surveillance and control on highly pathogenic avian influenza outbreaks in poultry in Dhaka division, Bangladesh

Hill, E. M.; House, T.; Dhingra, M. S.; Kalpravidh, W.; Morzaria, S.; Osmani, M. G.; Brum, E.; Yamage, M.; Kalam, M. A.; Prosser, D. J.; Takekawa, J. Y.; Xiao, X.; Gilbert, M.; Tildesley, M. J.

10.1101/193177 — epidemiology — Posted on 2018-02-06

1453 The dynamic core microbiome: Structure, dynamics and stability

Bjork, J. R.; O'Hara, R. B.; Ribes, M.; Coma, R.; Montoya, J. M.

10.1101/137885 — ecology — Posted on 2018-02-06

1454 Non-canonical apical constriction shapes emergent matrices in C. elegans

Katz, S. S.; Maybrun, C.; Frand, A. R.

10.1101/189951 — developmental biology — Posted on 2018-02-06

1455 Sensitivity analysis based ranking reveals unknown biological hypotheses for down regulated genes in time buffer during administration of PORCN-WNT inhibitor ETC-1922159 in CRC

Sinha, S.

10.1101/180927 — cancer biology — Posted on 2018-02-06

1456 Visualizing acto-myosin dynamics and vortices at a membrane surface using interferometric scattering microscopy

Koester, D.; Hundt, N.; Young, G. C.; Fineberg, A.; Kukura, P.; Mayor, S.

10.1101/199778 — biophysics — Posted on 2018-02-06

1457 Metabolic enzyme cost explains variable trade-offs between microbial growth rate and yield

Wortel, M. T.; Noor, E.; Ferris, M.; Bruggeman, F. J.; Liebermeister, W.

10.1101/111161 — systems biology — Posted on 2018-02-06

1458 Intronic CNVs cause gene expression variation in human population

Rigau, M.; Juan, D.; Valencia, A.; Rico, D.

10.1101/171165 — genomics — Posted on 2018-02-06

1459 Applying polygenic risk scoring for psychiatric disorders to a large family with Bipolar Disorder and Major Depressive Disorder

de Jong, S.; Abdalla Diniz, M. J.; Saloma Rodrigues, A. C.; Gadelha, A.; Santoro, M. L.; Ota, V. K.; Noto, C.; Psychiatric Genomics Consortium MDD & BIP groups, ; Curtis, C.; Patel, H.; Hall, L. S.; O'Reilly, P. F.; Belangero, S. I.; Bressan, R.; Breen, G.

10.1101/103713 — genetics — Posted on 2018-02-06

1460 Optimal Vaccination of a General Population Network via Genetic Algorithms

Sanders, L.; Woolley-Meza, O.

10.1101/227116 — epidemiology — Posted on 2018-02-06

1461 Going through the motions: incorporating movement analyses into disease research

Dougherty, E. R.; Seidel, D. P.; Carlson, C. J.; Speigel, O.; Getz, W. M.

10.1101/237891 — ecology — Posted on 2018-02-06

1462 pysster: Classification Of Biological Sequences By Learning Sequence And Structure Motifs With Convolutional Neural Networks

Budach, S.; Marsico, A.

10.1101/230086 — bioinformatics — Posted on 2018-02-06

1463 The role of Aβ circRNA in Alzheimer’s disease

Mo, D.

10.1101/260968 — neuroscience — Posted on 2018-02-06

1464 Theta bursts precede, and spindles follow, cortical and thalamic downstates in human NREM sleep

Gonzalez, C. E.; Mak-McCully, R.; Cash, S.; Chauvel, P.; Bastuji, H.; Rey, M.; Halgren, E.

10.1101/260786 — neuroscience — Posted on 2018-02-06

1465 The interplay of synaptic plasticity and scaling enables the self-organized allocation of multiple memory representations

Auth, J. M.; Nachstedt, T.; Tetzlaff, C.

10.1101/260950 — neuroscience — Posted on 2018-02-06

1466 Non-linear transfer characteristics of stimulation and recording hardware account for spurious low-frequency artifacts during amplitude modulated transcranial alternating current stimulation (AM-tACS)

Kasten, F. H.; Negahbani, E.; Frohlich, F.; Herrmann, C. S.

10.1101/246710 — neuroscience — Posted on 2018-02-06

1467 A new, phenotypically distinct subpopulation of Regulatory Killer T ex-Th17 cells expressing CD4lowCD25hiCD49hiFoxp3hiRORlowIL-17low

Sayapina, M.

10.1101/261073 — immunology — Posted on 2018-02-06

1468 Taxonomic Profiling and Populational Patterns of Bacterial Bile Salt Hydrolase (BSH) Genes on Worldwide Human Gut Microbiome

Li, J.; Jin, L.; Song, Z.; Cai, Y.; Wang, X.; Lin, X.; Cui, Y.; Shang, J.

10.1101/260794 — genomics — Posted on 2018-02-06

1469 Assessing the durability and efficiency of landscape-based strategies to deploy plant resistance to pathogens

Rimbaud, L.; Papaïx, J.; Rey, J.-F.; Barrett, L. G.; Thrall, P. H.

10.1101/260836 — evolutionary biology — Posted on 2018-02-06

1470 MSIGNET: a Metropolis sampling-based method for global optimal significant network identification

Chen, X.; Xuan, J.

10.1101/260844 — bioinformatics — Posted on 2018-02-06

1471 Direct-To-Consumer DNA testing of 6,000 dogs reveals 98.6-kb duplication causing blue eyes and heterochromia in Siberian Huskies

Deane-Coe, P. E.; Chu, E. T.; Boyko, A. R.; Sams, A. J.

10.1101/247973 — bioinformatics — Posted on 2018-02-06

1472 Allosteric Mechanism of the V. vulnificus Adenine Riboswitch Resolved by Four-dimensional Chemical Mapping

Tian, S.; Kladwang, W.; Das, R.

10.1101/157412 — biochemistry — Posted on 2018-02-06

1473 Individual- and population-level drivers of consistent foraging success across environments

Snijders, L.; Kurvers, R. H. J. M.; Krause, S.; Ramnarine, I. W.; Krause, J.

10.1101/260604 — animal behavior and cognition — Posted on 2018-02-06

1474 Naked mole-rat brain neurons have reduced ASIC-mediated currents and are resistant to acid-induced cell death

Husson, Z.; Smith, E. S. J.

10.1101/260901 — neuroscience — Posted on 2018-02-06

1475 Temporally unconstrained decoding reveals consistent but time-varying stages of stimulus processing

Vidaurre, D.; Myers, N.; Stokes, M.; Nobre, A. C.; Woolrich, M. W.

10.1101/260943 — neuroscience — Posted on 2018-02-06

1476 Evidence for the coupling of substrate recognition with transporter opening in MOP-family flippases

Sham, L.-T.; Zheng, S.; Kruse, A. C.; Bernhardt, T.

10.1101/260661 — microbiology — Posted on 2018-02-06

1477 Phylogeny Recapitulates Learning: Self-Optimization of Genetic Code

Attie, O.; Sulkow, B.; Di, C.; Qiu, W.

10.1101/260877 — evolutionary biology — Posted on 2018-02-06

1478 High carnivore population density highlights the conservation value of industrialised sites

Loock, D. J. E.; Williams, S. T.; Emslie, K. W.; Matthews, W. S.; Swanepoel, L. H.

10.1101/260729 — ecology — Posted on 2018-02-06

1479 Ximmer: A System for Improving Accuracy and Consistency of CNV Calling from Exome Data

Sadedin, S.; Ellis, J.; Masters, S.; Oshlack, A.

10.1101/260927 — bioinformatics — Posted on 2018-02-06

1480 Adaptive stimulus selection for multi-alternative psychometric functions with lapses

Bak, J. H.; Pillow, J. W.

10.1101/260976 — animal behavior and cognition — Posted on 2018-02-06

1481 Temperature-induced changes in wheat phosphoproteome reveal temperature-regulated interconversion of phosphoforms

Vu, L. D.; Zhu, T.; Verstraeten, I.; van de Cotte, B.; IWGSC, ; Gevaert, K.; De Smet, I.

10.1101/261065 — plant biology — Posted on 2018-02-06

1482 Template switching causes artificial junction formation and false identification of circular RNAs

Tang, C.; Yu, T.; Xie, Y.; Wang, Z.; McSwiggin, H.; Zhang, Y.; Zheng, H.; Yan, W.

10.1101/259556 — molecular biology — Posted on 2018-02-06

1483 Molecular basis of mitotic decline during human aging

Macedo, J. C.; Vaz, S.; Bakker, B.; Ribeiro, R.; Bakker, P.; Escandell, J. M.; Ferreira, M. G.; Medema, R.; Foijer, F.; Logarinho, E.

10.1101/261008 — cell biology — Posted on 2018-02-06

1484 Engineering Lipid Droplet Assembly Mechanisms for Improved Triacylglycerols Accumulation in S. cerevisiae

Teixeira, P. G.; David, F.; Siewers, V.; Nielsen, J.

10.1101/261057 — bioengineering — Posted on 2018-02-06

1485 Development of photoactivatable drugs enables nicotinic optopharmacology

Banala, S.; Arvin, M. C.; Bannon, N. M.; Jin, X.-T.; Wang, Y.; Zhao, G.; Marshall, J. J.; Gee, K. R.; Wokosin, D. L.; Contractor, A.; Henry, L. A.; Kozorovitskiy, Y.; Drenan, R. M.; Lavis, L. D.

10.1101/260232 — neuroscience — Posted on 2018-02-05

1486 PSF correction in soft x-ray tomography

Ekman, A.; Weinhardt, V.; Chen, J.-H.; McDermott, G.; Le Gros, M.; Larabell, C.

10.1101/260737 — cell biology — Posted on 2018-02-05

1487 Structure and mutagenic analysis of the lipid II flippase MurJ from Escherichia coli

Zheng, S.; Sham, L.-T.; Brock, K.; Robins, W. P.; Mekalanos, J. J.; Marks, D. S.; Bernhardt, T. G.; Kruse, A. C.

10.1101/260596 — biochemistry — Posted on 2018-02-05

1488 A Chemical Biology Toolbox for the Study of Protein Methyltransferases and Epigenetic Signaling

Scheer, S.; Ackloo, S.; Medina, T. S.; SCHAPIRA, M.; Li, F.; Ward, J. A.; Lewis, A. M.; Northrop, J. P.; Richardson, P. L.; Kaniskan, H. U.; Shen, Y.; Liu, J.; Smil, D.; Luo, M.; Jin, J.; Barsyte-Lovejoy, D.; Huber, K. V. M.; De Carvalho, D. D.; Vedadi, M.; Zaph, C.; Brown, P. J.; Arrowsmith, C. H.

10.1101/260638 — biochemistry — Posted on 2018-02-05

1489 Deep profiling of mouse splenic architecture with CODEX multiplexed imaging.

Goltsev, Y.; Samusik, N.; Kennedy-Darling, J.; Bhate, S.; Hale, M.; Vasquez, G.; Black, S.; Nolan, G.

10.1101/203166 — systems biology — Posted on 2018-02-05

1490 Mosaic representations of odors in the input and output layers of the mouse olfactory bulb

Chae, H.; Kepple, D.; Bast, W. G.; Murthy, V. N.; Koulakov, A.; Albeanu, D. F.

10.1101/259945 — neuroscience — Posted on 2018-02-05

1491 Measuring the reproducibility and quality of Hi-C data

Yardımcı, G. G.; Ozadam, H.; Sauria, M. E. G.; Ursu, O.; Yan, K.-K.; Yang, T.; Chakraborty, A.; Kaul, A.; Lajoie, B. R.; Song, F.; Zhan, Y.; Ay, F.; Gerstein, M.; Kundaje, A.; Li, Q.; Taylor, J.; Yue, F.; Dekker, J.; Noble, W. S.

10.1101/188755 — genomics — Posted on 2018-02-05

1492 Massive surface membrane expansion without involvement of classical exocytic mechanisms.

Fine, M.; Bricogne, C.; Hilgemann, D. W.

10.1101/249284 — cell biology — Posted on 2018-02-05

1493 Simulating human sleep spindle MEG and EEG from ion channel and circuit level dynamics

Rosen, B. Q.; Krishnan, G.; Sanda, P.; Komarov, M.; Sejnowski, T.; Rulkov, N.; Bazhenov, M.; Halgren, E.

10.1101/202606 — neuroscience — Posted on 2018-02-05

1494 Genomic imprinting mediates dosage compensation in a young plant XY system

Muyle, A.; Zemp, N.; Fruchard, C.; Cegan, R.; Vrana, J.; Deschamps, C.; Tavares, R.; Picard, F.; Hobza, R.; Widmer, A.; Marais, G.

10.1101/179044 — evolutionary biology — Posted on 2018-02-05

1495 Mosaic representations of odors in the input and output layers of the mouse olfactory bulb

Chae, H.; Kepple, D.; Bast, W. G.; Murthy, V. N.; Koulakov, A.; Albeanu, D. F.

10.1101/259945 — neuroscience — Posted on 2018-02-05

1496 The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice

Tong, D.; Chen, R.; Lu, Y.; Li, W.; Zhang, Y.; Lin, J.; He, L.; Dang, T.; Shan, S.; Xu, X.; Zhang, Y.; Zhang, C.; Du, Y.; Zhou, W.-H.; Wang, X.; Qiu, Z.

10.1101/260083 — neuroscience — Posted on 2018-02-05

1497 A proteolytic complex targets multiple cell wall hydrolases in Pseudomonas aeruginosa

Srivastava, D.; Seo, J.; Rimal, B.; Kim, S. J.; Darwin, A. J.

10.1101/260620 — microbiology — Posted on 2018-02-05

1498 Human mediated dispersal of cats in the Neolithic Central Europe

Baca, M.; Popovic, D.; Panagiotopoulou, H.; Marciszak, A.; Krajcarz, M.; Krajcarz, M. T.; Makowiecki, D.; Weglenski, P.; Nadachowski, A.

10.1101/259143 — ecology — Posted on 2018-02-05

1499 Increased autophagy in ephrinB2 deficient osteocytes is associated with hypermineralized, brittle bones

Vrahnas, C.; Dite, T. A.; Ansari, N.; Crimeen-Irwin, B.; Nguyen, H.; Forwood, M. R.; Hu, Y.; Ikegame, M.; Bambery, K. R.; Petibois, C.; Tobin, M. J.; Smyth, G. K.; Oakhill, J. S.; Martin, T. J.; Sims, N. A.

10.1101/260711 — cell biology — Posted on 2018-02-05

1500 RECAP reveals the true statistical significance of ChIP-seq peak calls

Chitpin, J. G.; Awdeh, A.; Perkins, T. J.

10.1101/260687 — bioinformatics — Posted on 2018-02-05

1501 Identification of parallel and divergent optimization solutions for homologous metabolic enzymes

Standaert, R. F.; Giannone, R. J.; Michener, J. K.

10.1101/260554 — bioengineering — Posted on 2018-02-05

1502 Reprogramming protein abundance fluctuations in single cells by degradation

Matalon, O.; Steinberg, A.; Sass, E.; Hausser, J.; Levy, E. D.

10.1101/260695 — systems biology — Posted on 2018-02-05

1503 Circulating unacylated-ghrelin impairs hippocampal neurogenesis and memory in mice and is altered in human Parkinson’s disease dementia

Hornsby, A. K. E.; Santos, V. V.; Johnston, F.; Roberts, L. D.; Stark, R.; Reichenbach, A.; Siervo, M.; Wells, T.; Andrews, Z. B.; Burn, D. J.; Davies, J. S.

10.1101/259333 — neuroscience — Posted on 2018-02-05

1504 Long-read sequencing reveals the splicing profile of the calcium channel gene CACNA1C in human brain

Clark, M.; Wrzesinski, T.; Garcia-Bea, A.; Kleinman, J.; Hyde, T.; Weinberger, D.; Haerty, W.; Tunbridge, E.

10.1101/260562 — neuroscience — Posted on 2018-02-05

1505 Using river temperature to optimize fish incubation metabolism and survival: a case for mechanistic models

Anderson, J. J.

10.1101/257154 — ecology — Posted on 2018-02-05

1506 Behaviors of microtubules depend on two critical concentrations

Jonasson, E. M.; Mauro, A. J.; Li, C.; Norby, E. C.; Mahserejian, S. M.; Scripture, J. P.; Gregoretti, I. V.; Alber, M. S.; Goodson, H.

10.1101/260646 — cell biology — Posted on 2018-02-05

1507 FastNet: Fast and accurate inference of phylogenetic networks using large-scale genomic sequence data

Hejase, H.; VandePol, N.; Bonito, G. M.; Liu, K. J.

10.1101/132795 — bioinformatics — Posted on 2018-02-05

1508 Protein-ligand interfaces are polarized: Discovery of a strong trend for intermolecular hydrogen bonds to favor donors on the protein side with implications for predicting and designing ligand complexes

Raschka, S.; Wolf, A. J.; Bemister-Buffington, J.; Kuhn, L. A.

10.1101/260612 — bioinformatics — Posted on 2018-02-05

1509 Linear Assembly of a Human Y Centromere

Jain, M.; Olsen, H. E.; Turner, D. J.; Stoddart, D.; Bulazel, K. V.; Paten, B.; Haussler, D.; Willard, H. F.; Akeson, M.; Miga, K. H.

10.1101/170373 — genomics — Posted on 2018-02-05

1510 Genetic basis of body color and spotting pattern in redheaded pine sawfly larvae (Neodiprion lecontei)

Linnen, C.; O'Quin, C. T.; Shackleford, T.; Sears, C. R.; Lindstedt, C.

10.1101/183996 — genetics — Posted on 2018-02-05

1511 Scaling read aligners to hundreds of threads on general-purpose processors

Langmead, B.; Wilks, C.; Antonescu, V.; Charles, R.

10.1101/205328 — bioinformatics — Posted on 2018-02-05

1512 Causal interactions from proteomic profiles: molecular data meets pathway knowledge

Babur, O.; Luna, A.; Korkut, A.; Durupinar, F.; Siper, M. C.; Dogrusoz, U.; Aslan, J. E.; Sander, C.; Demir, E.

10.1101/258855 — systems biology — Posted on 2018-02-05

1513 Two Novel Forms of ERG Oscillation in Drosophila: Age and Activity Dependence

Ueda, A.; Woods, S.; McElree, I.; O'Harrow, T. C. D. G.; Inman, C.; Thenuwara, S.; Aftab, M.; Iyengar, A.

10.1101/259952 — neuroscience — Posted on 2018-02-05

1514 Conceptual content in images triggers rapid shifts of covert attention

Wyble, B.; Hess, M.; Callahan-Flintoft, C.; Folk, C.

10.1101/259929 — neuroscience — Posted on 2018-02-05

1515 Real-time decoding of selective attention from the human auditory brainstem response to continuous speech

Etard, O.; Kegler, M.; Braiman, C.; Forte, A. E.; Reichenbach, T.

10.1101/259853 — neuroscience — Posted on 2018-02-05

1516 Non-Invasive Brain Stimulation to Investigate Language Production in Healthy Speakers: A Meta-Analysis

Klaus, J.; Schutter, D. J. L. G.

10.1101/230631 — neuroscience — Posted on 2018-02-05

1517 Peak gamma frequency and cortical laminar processing are modified across the healthy menstrual cycle

Sumner, R. L.; McMillan, R. L.; Shaw, A. D.; Singh, K. D.; Sundram, F.; Muthukumaraswamy, S.

10.1101/219196 — neuroscience — Posted on 2018-02-05

1518 Forty-Eight Hour Conditioning Produces A Robust Long Lasting Flavor Preference In Rats

Kimbrough, A.; Houpt, T. A.

10.1101/259804 — neuroscience — Posted on 2018-02-05

1519 Coupling MALDI-TOF mass spectrometry protein and specialized metabolite analyses to rapidly discriminate bacterial function

Clark, C. M.; Costa, M. S.; Sanchez, L. M.; Murphy, B. T.

10.1101/215350 — microbiology — Posted on 2018-02-05

1520 A novel combination of cyclophosphamide and anti-ICOS mAb prevents tumor growth by affecting regulatory T cells in mice with a human immune system

Burlion, A.; Ramos, R.; Sendeyo, K.; Corneau, A.; Caux, C.; Piaggio, E.; Olive, D.; Caux, C.; Marodon, G.

10.1101/191031 — immunology — Posted on 2018-02-05

1521 Gene Coregulation and Coexpression in the Aryl Hydrocarbon Receptor-mediated Transcriptional Regulatory Network in the Mouse Liver

Josyula, N.; Andersen, M. E.; Kaminski, N.; Dere, E.; Zacharewski, T. R.; Bhattacharya, S.

10.1101/260018 — genomics — Posted on 2018-02-05

1522 Atf3 links loss of epithelial polarity to defects in cell differentiation and cytoarchitecture

Donohoe, C. D.; Csordas, G.; Correia, A.; Jindra, M.; Klein, C.; Habermann, B.; Uhlirova, M.

10.1101/212969 — genetics — Posted on 2018-02-05

1523 Early Archean origin of heterodimeric Photosystem I

Cardona, T.

10.1101/225888 — evolutionary biology — Posted on 2018-02-05

1524 Estimation of age-specific susceptibility to influenza in the Netherlands and its relation to loss of CD8+ T-cell memory

van Dorp, C. H.; Woolthuis, R. G.; Yu, J. H. C.; De Boer, R. J.; van Boven, M.

10.1101/259614 — epidemiology — Posted on 2018-02-05

1525 Use of an individual-based model of pneumococcal carriage for planning a randomized trial of a vaccine

Cai, F. Y.; Fussell, T.; Cobey, S. E.; Lipsitch, M.

10.1101/258871 — epidemiology — Posted on 2018-02-05

1526 Education can Reduce Health Disparities Related to Genetic Risk of Obesity: Evidence from a British Reform

Barcellos, S. H.; Carvalho, L. S.; Turley, P.

10.1101/260463 — epidemiology — Posted on 2018-02-05

1527 Local adaptation primes cold-edge populationsfor range expansion but not warming-induced range shifts

Hargreaves, A. L.; Eckert, C. G.

10.1101/259879 — ecology — Posted on 2018-02-05

1528 In situ administration of cytokine combinations induces tumor regression

Zhang, J.; Jiang, H.; Zhang, H.

10.1101/260547 — cancer biology — Posted on 2018-02-05

1529 The role of conformational entropy in the determination of structural-kinetic relationships for helix-coil transitions

Rudzinski, J. F.; Bereau, T.

10.1101/237875 — biophysics — Posted on 2018-02-05

1530 TrackSig: reconstructing evolutionary trajectories of mutation signature exposure

Rubanova, Y.; Li, R.; Wintersinger, J.; Sahin, N.; Deshwar, A.; PCAWG-11 working group, ; Morris, Q.

10.1101/260471 — bioinformatics — Posted on 2018-02-05

1531 A Fast Adaptive Algorithm for Computing Whole-Genome Homology Maps

Jain, C.; Koren, S.; Dilthey, A.; Phillippy, A. M.; Aluru, S.

10.1101/259986 — bioinformatics — Posted on 2018-02-05

1532 Adaptive and Wireless Recordings of Electrophysiological Signals during Concurrent Magnetic Resonance Imaging

Mandal, R.; Babaria, N.; Cao, J.; Liu, Z.

10.1101/259762 — bioengineering — Posted on 2018-02-05

1533 Laminin heparin-binding peptides promiscuously bind growth factors and enhance diabetic wound healing

Ishihara, J.; Ishihara, A.; Fukunaga, K.; Briquez, P. S.; Hubbell, J. A.

10.1101/259481 — bioengineering — Posted on 2018-02-05

1534 Scopoletin Augments DJ1/Nrf2 Signalling and Prevents Protein Aggregation in Parkinson’s disease

Narasimhan, K. K.; Jayakumar, D.; Velusamy, P.; Srinivasan, A.; Mohan, T.; Ravi, D. B.; Uthamaraman, S.; Sathyamoorthy, Y. K.; Rajasekaran, N.-S.; Periandavan, K.

10.1101/260521 — biochemistry — Posted on 2018-02-05

1535 A tutorial on Bayesian parameter inference for dynamic energy budget models

Boersch-Supan, P. H.; Johnson, L. R.

10.1101/259705 — physiology — Posted on 2018-02-05

1536 Deep Convolutional Neural Networks for Breast Cancer Histology Image Analysis

Rakhlin, A.; Shvets, A.; Iglovikov, V.; Kalinin, A.

10.1101/259911 — pathology — Posted on 2018-02-05

1537 Neurocognitive Aging and Brain Signal Complexity

McIntosh, A.

10.1101/259713 — neuroscience — Posted on 2018-02-05

1538 The national alert-response strategy against cholera in Haiti: a four-year assessment of its implementation

Rebaudet, S.; Bulit, G.; Gaudart, J.; Michel, E.; Gazin, P.; Evers, C.; Beaulieu, S.; Abedi, A. A.; Osei, L.; Barrais, R.; Pierre, K.; Moore, S.; Boncy, J.; Adrien, P.; Beigbeder, E.; Duperval Guillaume, F.; Piarroux, R.

10.1101/259366 — epidemiology — Posted on 2018-02-05

1539 Choices in Vaccine Trial Design for Epidemics of Emerging Infections

Kahn, R.; Rid, A.; Smith, P. G.; Eyal, N.; Lipsitch, M.

10.1101/259606 — epidemiology — Posted on 2018-02-05

1540 Data-based, synthesis-driven: setting the agenda for computational ecology

Poisot, T.; Labrie, R.; Larson, E.; Rahlin, A.

10.1101/150128 — ecology — Posted on 2018-02-05

1541 Brain Development: Machine Learning Analysis Of Individual Stem Cells In Live 3D Tissue

Hailstone, M.; Yang, L.; Waithe, D.; Samuels, T. J.; Arava, Y.; Dobrzycki, T.; Parton, R. M.; Davis, I.

10.1101/137406 — developmental biology — Posted on 2018-02-05

1542 Log D Analysis using Dynamic approach

Krishnamoorthy, J.; Krishnamoorthy, G. K.; Alluvada, P.; Alemayehu, E.; hameed, S.; Alemayehu, W.; Kwa, T.

10.1101/259770 — biophysics — Posted on 2018-02-05

1543 Physiological motion of the carotid atherosclerotic plaque quantified using ultrasound B-Mode image analysis

Kanber, B.; Hartshorne, T. C.; Garrard, J. W.; Naylor, R. A.; Robinson, T. G.; Ramnarine, K. V.

10.1101/255232 — biophysics — Posted on 2018-02-05

1544 Molecular Typing with COI - DNA Barcode of mosquitoes with medical importance from rural area from La Pintada, Antioquia, Colombia

Hoyos-Lopez, R.

10.1101/260505 — zoology — Posted on 2018-02-05

1545 HRS1/HHOs GARP transcription factors and reactive oxygen species are regulators of Arabidopsis nitrogen starvation response.

Safi, A.; Medici, A.; Szponarski, W.; Marshall-Colon, A.; Ruffel, S.; Gaymard, F.; Coruzzi, G.; Lacombe, B.; Krouk, G.

10.1101/164277 — plant biology — Posted on 2018-02-05

1546 2,4-Diaminothienopyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm

Partridge, F. A.; Forman, R.; Willis, N. J.; Bataille, C. J.; Murphy, E. A.; Brown, A. E.; Heyer-Chauhan, N.; Marinic, B.; Sowood, D. J.; Wynne, G. M.; Else, K. J.; Russell, A. J.; Sattelle, D. B.

10.1101/254037 — pharmacology and toxicology — Posted on 2018-02-05

1547 Modulation of slow and fast oscillations by direct current stimulation in the cerebral cortex in vitro

D'Andola, M.; Weinert, J. F.; Mattia, M.; Sanchez-Vives, M. V.

10.1101/246819 — neuroscience — Posted on 2018-02-05

1548 Beyond the vestibulo-ocular reflex: Vestibular input is processed centrally to achieve visual stability

Dalmaijer, E. S.

10.1101/260299 — neuroscience — Posted on 2018-02-05

1549 Modeling driver cells in developing neuronal networks

Luccioli, S.; Angulo-Garcia, D.; Cossart, R.; Malvache, A.; Modol, L.; Sousa, V. H.; Bonifazi, P.; Torcini, A.

10.1101/260422 — neuroscience — Posted on 2018-02-05

1550 First Efficient Transfection in Choanoflagellates using Cell-Penetrating Peptides

Li, R.; Neundorf, I.; Nitsche, F.

10.1101/260190 — molecular biology — Posted on 2018-02-05

1551 Chromosome-scale comparative sequence analysis unravels molecular mechanisms of genome evolution between two wheat cultivars

10.1101/260406 — genomics — Posted on 2018-02-05

1552 MirGeneDB2.0: the curated microRNA Gene Database

Fromm, B.; Domanska, D.; Hackenberg, M.; Mathelier, A.; Hoye, E.; Johansen, M.; Hovig, E.; Flatmark, K.; Peterson, K. J.

10.1101/258749 — genomics — Posted on 2018-02-05

1553 Genome-wide epigenetic profiling of 5-hydroxymethylcytosine by long-read optical mapping

Gabrieli, T.; Sharim, H.; Nifker, G.; Jeffet, J.; Shahal, T.; Arielly, R.; Levy-Sakin, M.; Hoch, L.; Arbib, N.; Michaeli, Y.; Ebenstein, Y.

10.1101/260166 — genomics — Posted on 2018-02-05

1554 A transcript-wide association study in physical activity intervention implicates molecular pathways in chronic disease

Claypool, K.; Patel, C. J.

10.1101/260398 — genomics — Posted on 2018-02-05

1555 Genetic Instrumental Variable (GIV) Regression: Explaining Socioeconomic And Health Outcomes In Non-Experimental Data

DiPrete, T. A.; Burik, C. A. P.; Koellinger, P. D.

10.1101/134197 — genetics — Posted on 2018-02-05

1556 Sexual isolation with and without ecological isolation between sympatric isopods Jaera albifrons and J. praehirsuta

Ribardiere, A.; Pabion, E.; Coudret, J.; Daguin-Thiebaut, C.; Houbin, C.; Loisel, S.; Henry, S.; Broquet, T.

10.1101/260489 — evolutionary biology — Posted on 2018-02-05

1557 Haemolymph removal by the parasite Varroa destructor can trigger the proliferation of the Deformed Wing Virus in mite infested bees (Apis mellifera), contributing to enhanced pathogen virulence

Annoscia, D.; Brown, S.; Di Prisco, G.; De Paoli, E.; Del Fabbro, S.; Zanni, V.; Galbraith, D.; Caprio, E.; Grozinger, C. M.; Pennacchio, F.; Nazzi, F.

10.1101/257667 — ecology — Posted on 2018-02-05

1558 Life history variation along an elevational gradient in Plethodon montanus: implications for conservation

Caruso, N. M.; Rissler, L. J.

10.1101/130922 — ecology — Posted on 2018-02-05

1559 Ultrastructure of viruliferous Javesella pellucida transmitting Festuca leaf streak virus (genus Cytorhabdovirus)

Lundsgaard, T.

10.1101/258483 — cell biology — Posted on 2018-02-05

1560 Vasohibin1, a new IRES trans-acting factor for sequential induction of angiogenic factors in hypoxia

Prats, A.-C.; Hantelys, F.; Godet, A.-C.; Tatin, F.; Renaud-Gabardos, E.; Pujol, F.; Ader, I.; Ligat, L.; Henras, A.; Lacazette, E.; Parini, A.; Garmy-Susini, B.

10.1101/260364 — cell biology — Posted on 2018-02-05

1561 Lysosome expansion by selective translation of lysosomal transcripts during phagocyte activation

Hipolito, V. E. B.; Diaz, J.; Tandoc, K.; Saric, A.; Toposiviric, I.; Botelho, R.

10.1101/260257 — cell biology — Posted on 2018-02-05

1562 Fission yeast cells overproducing HSET/KIFC1 provides a useful tool for identification and evaluation of human kinesin-14 inhibitors

Yukawa, M.; Yamauchi, T.; Kimura, K.-i.; Toda, T.

10.1101/257436 — cell biology — Posted on 2018-02-05

1563 Interconnected feedback loops among ESRP1, HAS2, and CD44 regulate epithelial-mesenchymal plasticity in cancer

Jolly, M. K.; Preca, B.-T.; Tripathi, S. C.; Jia, D.; Hanash, S. M.; Brabletz, T.; Stemmler, M. P.; Maurer, J.; Levine, H.

10.1101/260349 — cancer biology — Posted on 2018-02-05

1564 Conservation of conformational dynamics across prokaryotic actins

Ng, N.; Shi, H.; Colavin, A.; Huang, K.

10.1101/260208 — biophysics — Posted on 2018-02-05

1565 The interplay of immune components and ECM in oral cancer

Kwak, Y.; Alsaihati, B.; Zhang, C.; Xu, Y.; Cao, S.

10.1101/259622 — bioinformatics — Posted on 2018-02-05

1566 Predicting Enhancer-Promoter Interaction from Genomic Sequence with Deep Neural Networks

Singh, S.; Yang, Y.; Poczos, B.; Ma, J.

10.1101/085241 — bioinformatics — Posted on 2018-02-05

1567 Metabolic pairing of aerobic and anaerobic production in a one-pot batch cultivation

Salmela, M.; Lehtinen, T.; Efimova, E.; Santala, S. M.; Mangayil, R.

10.1101/260216 — bioengineering — Posted on 2018-02-05

1568 The N-terminus of Sec61p plays key roles in ER protein import and ERAD

Elia, F.; Tretter, T.; Romisch, K.

10.1101/260174 — biochemistry — Posted on 2018-02-05

1569 Cognition and behaviour in learning difficulties and ADHD: A dimensional approach

Gathercole, S. E.; Astle, D. A.; Manly, T.; the CALM Team, ; Holmes, J.

10.1101/260265 — animal behavior and cognition — Posted on 2018-02-05

1570 Automatic Cell Segmentation by Adaptive Thresholding (ACSAT) for large scale calcium imaging datasets

Shen, S. P.; Tseng, H.-a.; Hansen, K. R.; Wu, R.; Gritton, H.; Si, J.; Han, X.

10.1101/260075 — neuroscience — Posted on 2018-02-05

1571 What drives interaction strengths in complex food webs? A test with feeding rates of a generalist stream predator

Preston, D.; Henderson, J.; Falke, L.; Segui, L.; Layden, T.; Novak, M.

10.1101/259697 — ecology — Posted on 2018-02-05

1572 Conbase: a software for discovery of clonal somatic mutations in single cells through read phasing

Hard, J.; Al Hakim, E.; Kindblom, M.; Bjorklund, A.; Demirci, I.; Paterlini, M.; Sennblad, B.; Borgstrom, E.; Stahl, P. L.; Michaelsson, J.; Mold, J. E.; Frisen, J.

10.1101/259994 — bioinformatics — Posted on 2018-02-05

1573 Modulation of defence and iron homeostasis genes in rice roots by the diazotrophic endophyte Herbaspirillum seropedicae

Brusamarello-Santos, L. C. C.; Alberton, D.; Valdameri, G.; Camilios-Neto, D.; Covre, R.; Lopes, K.; Tadra-Sfeir, M. Z.; Faoro, H.; Monteiro, R. A.; Silva, A. B.; Broughton, W. J.; Pedrosa, F. O.; Wassem, R.; Souza, E. M.

10.1101/260380 — plant biology — Posted on 2018-02-05

1574 Kaptive Web: user-friendly capsule and lipopolysaccharide serotype prediction for Klebsiella genomes

Wick, R. R.; Heinz, E.; Holt, K. E.; Wyres, K. L.

10.1101/260125 — microbiology — Posted on 2018-02-05

1575 Spatiotemporal dynamics of river viruses, bacteria and microeukaryotes

Van Rossum, T.; Uyaguari-Diaz, M. I.; Vlok, M.; Peabody, M. A.; Tian, A.; Cronin, K. I.; Chan, M.; Croxen, M. A.; Hsiao, W. W.; Isaac-Renton, J.; Tang, P. K.; Prystajecky, N. A.; Suttle, C. A.; Brinkman, F. S.

10.1101/259861 — microbiology — Posted on 2018-02-05

1576 Selection of appropriate metagenome taxonomic classifiers for ancient microbiome research

Velsko, I. M.; Frantz, L. A. F.; Herbig, A.; Larson, G.; Warinner, C.

10.1101/260042 — microbiology — Posted on 2018-02-05

1577 New insights on human essential genes based on integrated multi-omics analysis

Chen, H.; Zhang, Z.; Jiang, S.; Li, R.; Li, W.; Li, H.; Bo, X.

10.1101/260224 — genomics — Posted on 2018-02-05

1578 The TRIM-NHL protein NHL-2 is a Novel Co-Factor of the CSR-1 and HRDE-1 22G-RNA Pathways

Boag, P. R.; Davis, G. M.; Tu, S.; Colson, R. N.; Anderson, J. W. T.; Gunzburg, M. J.; Francisco, M. A.; Ray, D.; Maity, T.; Wu, M. Z.; Morris, Q. D.; Hughes, T. R.; Wilce, J. A.; Claycomb, J.; Weng, Z.

10.1101/260240 — genetics — Posted on 2018-02-05

1579 Endoderm Morphogenesis Reveals Integration of Distinct Processes in the Development and Evolution of Pharyngeal Arches

Takada, S.; Okada, K.; Wada, H.

10.1101/260356 — developmental biology — Posted on 2018-02-05

1580 Case-control analysis identifies shared properties of rare germline variation in cancer predisposing genes

Artomov, M.; Joseph, V.; Tiao, G.; Thomas, T.; Schrader, K.; Klein, R. J.; Kiezun, A.; Gupta, N.; Margolin, L.; Stratigos, A. J.; Kim, I.; Shannon, K.; Ellisen, L. W.; Haber, D.; Getz, G.; Tsao, H.; Lipkin, S. M.; Altshuler, D.; Offit, K.; Daly, M. J.

10.1101/162479 — genetics — Posted on 2018-02-04

1581 Characterising the short-term habituation of event-related evoked potentials

Mancini, F.; Pepe, A.; Di Stefano, G.; Mouraux, A.; Iannetti, G. D.

10.1101/153387 — neuroscience — Posted on 2018-02-04

1582 Estimating Heritability and Genetic Correlation in Case Control Studies Directly and with Summary Statistics

Weissbrod, O.; Flint, J.; Rosset, S.

10.1101/256388 — genetics — Posted on 2018-02-04

1583 Cold shock as a screen for genes involved in cold acclimatization in Neurospora crassa

Watters, M. K.; Manzanilla, V.; Howell, H.; Mehreteab, A.; Rose, E.; Walters, N.; Seitz, N.; Nava, J.; Kekelik, S.; Knuth, L.; Scivinsky, B.

10.1101/259580 — cell biology — Posted on 2018-02-04

1584 Using Current-flow Scheme to Capture Protein Allosteric Regulation

Botello-Smith, W. M.; Luo, Y.

10.1101/259572 — biophysics — Posted on 2018-02-04

1585 Atomic Resolution Mechanism of Ligand Binding to a Solvent Inaccessible Cavity in T4 Lysozyme

Mondal, J.; Ahalawat, N.; Pandit, S.; Kay, L. E.; Vallurupalli, P.

10.1101/259549 — biophysics — Posted on 2018-02-04

1586 Defect-Facilitated Buckling in Supercoiled Double-Helix DNA

Brahmachari, S.; Dittmore, A.; Takagi, Y.; Neuman, K. C.; Marko, J. F.

10.1101/259689 — biophysics — Posted on 2018-02-04

1587 Probe Efficient Feature Representation of Gapped K-mer Frequency Vectors from Sequences using Deep Neural Networks

Cao, Z.; Zhang, S.

10.1101/170761 — bioinformatics — Posted on 2018-02-04

1588 CITGeneDB: A comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice

Li, J.; Deng, S.-P.; Wei, G.; Yu, P.

10.1101/250514 — bioinformatics — Posted on 2018-02-04

1589 A robot-based gait training therapy for pediatric population with Cerebral Palsy: goal setting, proposal and preliminary clinical implementation

Bayon, C.; Martin-Lorenzo, T.; Moral-Saiz, B.; Ramirez, O.; Perez-Somarriba, A.; Lerma-Lara, S.; Martinez-Caballero, I.; Rocon, E.

10.1101/255448 — bioengineering — Posted on 2018-02-04

1590 Crystallizing the Parkinson’s Disease Protein LRRK2 Under Microgravity Conditions

Mattea, S.; Baptista, M.; Reichert, P.; Spinale, A.; Wu, J.; Allaire, M.; Fiske, B.; Knapp, S.

10.1101/259655 — biochemistry — Posted on 2018-02-04

1591 Defective RNA Polymerase III is negatively regulated by the SUMO-Ubiquitin-Cdc48 Pathway

Wang, Z.; Wu, C.; Aslanian, A.; Hunter, T.; Yates, J. R.

10.1101/259846 — biochemistry — Posted on 2018-02-04

1592 Design Principles of Lambda’s Lysis/lysogeny Decision vis-a-vis Multiplicity of Infection

Wadhwa, D.

10.1101/146308 — systems biology — Posted on 2018-02-04

1593 Independent control of slow and fast flight manoeuvres in insects: the roles of vision and antennal mechanoreception

Dahake, A.; Stoeckl, A.; Foster, J.; Sane, S. P.; Kelber, A.

10.1101/222448 — neuroscience — Posted on 2018-02-04

1594 Ultrasound elicits behavioral responses through mechanical effects on neurons and ion channels in a simple nervous system

Kubanek, J.; Shukla, P.; Das, A.; Baccus, S.; Goodman, M. B.

10.1101/104463 — neuroscience — Posted on 2018-02-04

1595 Time efficient preparation methods for MRI brain scanning in awake young children and factors associated with success

Thieba, C.; Frayne, A.; Walton, M.; Mah, A.; Benischek, A.; Dewey, D.; Lebel, C.

10.1101/259358 — neuroscience — Posted on 2018-02-04

1596 Local Cortical Activity Of Distant Brain Areas Can Time-Lock To The Respiratory Rhythm In The Freely Behaving Rat

Rojas-Libano, D.; Wimmer del Solar, J.; Aguilar, M.; Montefusco-Siegmund, R.; Maldonado, P. E.

10.1101/259457 — neuroscience — Posted on 2018-02-04

1597 Apolipoprotein L1 Dynamics in Human Parietal Epithelial Cell Molecular Phenotype Kinetics

Kumar, V.; Vashistha, H.; Lan, X.; Chandel, N.; Ayasolla, K.; Aslam, R.; Marshi Shoshtari, S. S.; Paliwal, N.; Abbruscato, F.; Mikulak, J.; Popik, W.; Malhotra, A.; Meyer-Scwesinger, C.; Skorecki, K.; Singhal, P. C.

10.1101/259267 — molecular biology — Posted on 2018-02-04

1598 Impacts of temperature on Zika virus transmission potential: combining empirical and mechanistic modeling approaches

Tesla, B.; Demakovsky, L. R.; Mordecai, E. A.; Bonds, M. H.; Ngonghala, C. N.; Brindley, M. A.; Murdock, C. C.

10.1101/259531 — ecology — Posted on 2018-02-04

1599 On the origin of the odorant receptor gene family in insects: evidence from the dragonfly Ladona fulva and the mayfly Ephemera danica

Robertson, H. M.

10.1101/259424 — bioinformatics — Posted on 2018-02-04

1600 GSEA-InContext: Identifying novel and common patterns in expression experiments

Powers, R.; Goodspeed, A.; Pielke-Lombardo, H.; Tan, A. C.; Costello, J.

10.1101/259440 — bioinformatics — Posted on 2018-02-04

1601 Experimental Zika Virus Infection in the Pregnant Common Marmoset Induces Spontaneous Fetal Loss and Neurodevelopmental Abnormalities

Seferovic, M.; Sanchez-SanMartin, C.; Tardif, S. D.; Rutherford, J.; Castro, E. C. C.; Li, T.; Hodara, V. L.; Parodi, L. M.; Giavedoni, L.; Layne-Colon, D.; Tamhankar, M.; Yagi, S.; Martyn, C.; Reyes, K.; Suter, M.; Aagaard, K. M.; Chiu, C. Y.; Patterson, J. L.

10.1101/259317 — microbiology — Posted on 2018-02-04

1602 GITAR: An open source tool for analysis and visualization of Hi-C data

Calandrelli, R.; Wu, Q.; Guan, J.; Zhong, S.

10.1101/259515 — bioinformatics — Posted on 2018-02-04

1603 Variable training but not sleep improves consolidation of motor adaptation

Thuerer, B.; Weber, F.; Born, J.; Stein, T.

10.1101/259671 — neuroscience — Posted on 2018-02-04

1604 Acetate is generated de novo from glucose metabolism in mammals and is coupled to central carbon metabolism

Liu, X.; Cooper, D. E.; Cluntun, A. A.; Warmoes, M. O.; Zhao, S.; Reid, M. A.; Liu, J.; Wellen, K. E.; Kirsch, D. G.; Locasale, J. W.

10.1101/259523 — biochemistry — Posted on 2018-02-04

1605 Determination of growth-coupling strategies and their underlying principles

Alter, T. B.; Blank, L. M.; Ebert, B. E.

10.1101/258996 — systems biology — Posted on 2018-02-03

1606 Integrated transcriptomics and metabolomics reveal signatures of lipid metabolism dysregulation in HepaRG liver cells exposed to PCB 126

Mesnage, R.; Biserni, M.; Balu, S.; Frainay, C.; Poupin, N.; Jourdan, F.; Wozniak, E.; Xenakis, T.; Mein, C. A.; Antoniou, M. A.

10.1101/259093 — pharmacology and toxicology — Posted on 2018-02-03

1607 Predicting functional networks from region connectivity profiles in task-based versus resting-state fMRI data

Rasero Daparte, J.; Aerts, H.; Cortes, J. M.; Stramaglia, S.; Marinazzo, D.

10.1101/259077 — neuroscience — Posted on 2018-02-03

1608 Context-dependent signaling of coincident auditory and visual events in primary visual cortex

Deneux, T.; Kempf, A.; Bathellier, B.

10.1101/258970 — neuroscience — Posted on 2018-02-03

1609 Loss of SDHB reprograms energy metabolisms and inhibits high fat diet induced metabolic syndromes

Zhu, Y.; Chen, Q.; Mu, C.; Ma, B.; Zhang, C.; Geng, G.; Zhang, X.; Chen, L.; Wang, M.; Li, J.; Zhao, T.; Zhang, Q.; Cheng, H.; Ma, K.; Luo, Q.; Chang, R.; Liu, Q.; Wu, H.; Liu, L.; Wang, J.; Wang, X.; Zhang, Y.; Wen, L.; Zhao, Y.

10.1101/259226 — molecular biology — Posted on 2018-02-03

1610 Thermoelectric Heat Exchange and Growth Regulation in a Continuous Yeast Culture

Latorre-Perez, A.; Vilanova, C.; J Alcaina, J.; Porcar, M.

10.1101/258962 — microbiology — Posted on 2018-02-03

1611 How to make use of ordination methods to identify local adaptation: a comparison of genome scans based on PCA and RDA

Capblancq, T.; Luu, K.; Blum, M.; Bazin, E.

10.1101/258988 — genomics — Posted on 2018-02-03

1612 Estimating Heritability and Genetic Correlation in Case Control Studies Directly and with Summary Statistics

Weissbrod, O.; Flint, J.; Rosset, S.

10.1101/256388 — genetics — Posted on 2018-02-03

1613 Doxorubicin induces caspase-mediated proteolysis of KV7.1

Strigli, A.; Schwake, M.; Raab, C.; Hessler, S.; Huth, T.; Schuldt, A. J. T.; Alzheimer, C.; Friedrich, T.; Burrdige, P. W.; Luedde, M.

10.1101/259242 — biochemistry — Posted on 2018-02-03

1614 Adaptive coding for dynamic sensory inference

Mlynarski, W.; Hermundstad, A. M.

10.1101/189506 — neuroscience — Posted on 2018-02-03

1615 Functional Parcellation of the Default Mode Network: A Large-Scale Meta-Analysis

Wang, S.; Taren, A. A.; Smith, D. V.

10.1101/225375 — neuroscience — Posted on 2018-02-03

1616 Rapid, noninvasive, and unsupervised detection of sleep/wake using piezoelectric monitoring for pharmacological studies in narcoleptic mice

Black, S. W.; Sun, J. D.; Laihsu, A.; Kimura, N.; Santiago, P.; Donohue, K. D.; O'Hara, B. F.; Bersot, R.; Humphries, P. S.

10.1101/226522 — neuroscience — Posted on 2018-02-03

1617 Listeria monocytogenes InlP interacts with afadin and facilitates basement membrane crossing

Faralla, C.; Bastounis, E. E.; Ortega, F. E.; Light, S. H.; Rizzuto, G.; Nocadello, S.; Anderson, W. F.; Robbins, J. R.; Theriot, J. A.; Bakardjiev, A. I.

10.1101/242222 — microbiology — Posted on 2018-02-03

1618 Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci

Thurner, M.; van de Bunt, M.; Torres, J. M.; Mahajan, A.; Nylander, V.; Bennett, A. J.; Gaulton, K.; Barrett, A.; Burrows, C.; Bell, C. G.; Lowe, R.; Beck, S.; Rakyan, V. K.; Gloyn, A. L.; McCarthy, M. I.

10.1101/190892 — genomics — Posted on 2018-02-03

1619 Association of Polygenic Risk Scores for Multiple Cancers in a Phenome-wide Study: Results from The Michigan Genomics Initiative

Fritsche, L. G.; Gruber, S. B.; Wu, Z.; Schmidt, E. M.; Zawistowski, M.; Moser, S. E.; Blanc, V. M.; Brummett, C. M.; Kheterpal, S.; Abecasis, G. R.; Mukherjee, B.

10.1101/205021 — genetics — Posted on 2018-02-03

1620 Reconstruction of atomistic structures from coarse-grained models for protein-DNA complexes

Shimizu, M.; Takada, S.

10.1101/205062 — biophysics — Posted on 2018-02-03

1621 Evaluating Internal Model Strength and Performance of Myoelectric Prosthesis Control Strategies

Shehata, A. W.; Scheme, E. J.; Sensinger, J. W.

10.1101/194225 — bioengineering — Posted on 2018-02-03

1622 In vivo cross-linking and transmembrane helix dynamics support a bidirectional non-piston model of signaling within E. coli EnvZ

Yusuf, R.; Nguyen, T. L.; Heininger, A.; Lawrence, R. J.; Hall, B. A.; Draheim, R. R.

10.1101/206888 — biochemistry — Posted on 2018-02-03

1623 Case-control analysis identifies shared properties of rare germline variation in cancer predisposing gene

10.1101/162479 — genetics — Posted on 2018-02-03

1624 Synthesis Of Extracellular Stable Gold Nanoparticles By Cupriavidus metallidurans CH34 Cells

Montero-Silva, F.

10.1101/139949 — biochemistry — Posted on 2018-02-03

1625 Sent to the Corner: xylem vessel anatomy not surface area determines megaphyll hydraulics in Cecropia obtusa Trecul (Urticaceae)

Levionnois, S.; Coste, S.; Nicolini, E.; Stahl, C.; Morel, H.; Heuret, P.

10.1101/259036 — plant biology — Posted on 2018-02-03

1626 Developmental chromatin restriction of pro-growth gene networks acts as an epigenetic barrier to axon regeneration in cortical neurons

Venkatesh, I.; Mehra, V.; Wang, Z.; Califf, B.; Blackmore, M.

10.1101/259408 — neuroscience — Posted on 2018-02-03

1627 Convergent evolution of gene expression in two high-toothed stickleback populations

Hart, J. C.; Ellis, N. A.; Eisen, M. B.; Miller, C. T.

10.1101/259499 — genomics — Posted on 2018-02-03

1628 INKA, an integrative data analysis pipeline for phosphoproteomic inference of active phosphokinases

Pham, T. V.; Beekhof, R.; van Alphen, C.; Knol, J. C.; Henneman, A. A.; Rolfs, F.; Labots, M.; Henneberry, E.; Le Large, T. Y.; de Haas, R. R.; Piersma, S. R.; Verheul, H.; Jimenez, C. R.

10.1101/259192 — systems biology — Posted on 2018-02-02

1629 Rationally-engineered reproductive barriers using CRISPR & CRISPRa: an evaluation of the synthetic species concept in Drosophila melanogaster

Waters, A. J.; Capriotti, P.; Gaboriau, D.; Papathanos, P. A.; Windbichler, N.

10.1101/259010 — synthetic biology — Posted on 2018-02-02

1630 T cell immunity does not age in a long-lived rodent species

Izraelson, M.; Nakonechnaya, T. O.; Davydov, A. N.; Dronina, M. A.; Miskevich, D. A.; Mamedov, I. Z.; Barbashova, L. N.; Shugay, M.; Bolotin, D.; Staroverov, D. B.; Kondratyuk, E. Y.; Bogdanova, E. A.; Lukyanov, S.; Shams, I.; Britanova, O. V.; Chudakov, D. M.

10.1101/259374 — immunology — Posted on 2018-02-02

1631 Long-range Notch-mediated tissue patterning requires actomyosin contractility

Hunter, G.; He, L.; Perrimon, N.; Charras, G.; Giniger, E.; Baum, B.

10.1101/259341 — developmental biology — Posted on 2018-02-02

1632 The Trials and Tribulations of Priors and Posteriors in Bayesian Timing of Divergence Analyses: the Age of Butterflies Revisited

Chazot, N.; Wahlberg, N.; Freitas, A. V.; Mitter, C.; Labandeira, C.; Sohn, J.-C.; Sahoo, R. K.; Seraphim, N.; de Jong, R.; Heikkila, M.

10.1101/259184 — evolutionary biology — Posted on 2018-02-02

1633 Disentangling eco-evolutionary effects on trait fixation

Czuppon, P.; Gokhale, C. S.

10.1101/259069 — evolutionary biology — Posted on 2018-02-02

1634 MVP: predicting pathogenicity of missense variants by deep neural networks

Qi, H.; Chen, C.; Zhang, H.; Long, J. J.; Chung, W. K.; Guan, Y.; Shen, Y.

10.1101/259390 — bioinformatics — Posted on 2018-02-02

1635 Candidate SNP analyses integrated with mRNA expression and hormone levels reveal influence on mammographic density and breast cancer risk

Biong, M.; Suderman, M.; Drageset Haakensen, V.; Kulle, B.; Berg, P.; Gram, I.-T.; Dumeaux, V.; Ursin, G.; Helland, A.; Hallet, M.; Borresen-Dale, A.-L.; Kristensen, V. N.

10.1101/259002 — genomics — Posted on 2018-02-02

1636 The Rate of Observable Molecular Evolution When Mutation May Not Be Weak

de Koning, A. P. J.; De Sanctis, B. D.

10.1101/259507 — genetics — Posted on 2018-02-02

1637 Xist Intron 1 Repression by TALE Transcriptional Factor Improves Somatic Cell Reprogamming in Mice

Zhang, J.; Gao, X.; Yang, J.; Fan, X.; Wang, W.; Liang, Y.; Fan, L.; Han, H.; Xu, X.; Tang, F.; Bao, S.; Liu, P.; Li, X.

10.1101/259234 — developmental biology — Posted on 2018-02-02

1638 H3K9 methylation maintains female identity in Drosophila germ cells through repression of the spermatogenesis program

Smolko, A.; Shapiro-Kulnane, L.; Salz, H.

10.1101/259473 — developmental biology — Posted on 2018-02-02

1639 Predicting CTCF-mediated chromatin loops using CTCF-MP

Zhang, R.; Wang, Y.; Yang, Y.; Zhang, Y.; Ma, J.

10.1101/259416 — bioinformatics — Posted on 2018-02-02

1640 Super-multiplexed fluorescence microscopy via photostability contrast

Orth, A.; Ghosh, R. N.; Wilson, E. R.; Doughney, T.; Brown, H.; Reineck, P.; Thompson, J.; Gibson, B. C.

10.1101/258889 — bioengineering — Posted on 2018-02-02

1641 Detection of Pro-apoptotic BaxΔ2 Proteins in the Human Cerebellum

Manas, A.; Davis, A.; Lamerand, S.; Xiang, J.

10.1101/245910 — cell biology — Posted on 2018-02-02

1642 CLIC4 is regulated by RhoA-mDia2 signaling through Profilin-1 binding to modulate filopodia length

Argenzio, E.; Kedziora, K. M.; Nahidiazar, L.; Isogai, T.; Perrakis, A.; Jalink, K.; Moolenaar, W. H.; Innocenti, M.

10.1101/259259 — cell biology — Posted on 2018-02-02

1643 Synaptic release of acetylcholine rapidly suppresses cortical activity by recruiting muscarinic receptors in layer 4

Dasgupta, R.; Seibt, F. M.; Beierlein, M.

10.1101/257980 — neuroscience — Posted on 2018-02-02

1644 Osteoclasts control sensory neurons axonal growth through epidermal growth factor receptor signaling

Neto, E.; Sousa, D.; Conceicao, F.; Leitao, L.; Alves, C. J.; Alencastre, I.; West, J.; Oreffo, R. O. C.; Lamghari, M.

10.1101/259218 — cell biology — Posted on 2018-02-02

1645 Inhibitor of apoptosis proteins determine glioblastoma stem-like cells fate depending on oxygen level

Souberan, A.; Cappai, J.; Chocry, M.; Nuccio, C.; Raujol, J.; Colin, C.; Lafitte, D.; Kovacic, H.; Quillien, V.; Baeza-Kallee, N.; Rougon, G.; Figarella-Branger, D.; Tchoghandjian, A.

10.1101/259283 — cancer biology — Posted on 2018-02-02

1646 Partial ablation of the orexin field induces a subnarcoleptic phenotype in a conditional mouse model of orexin neurodegeneration

Black, S. W.; Sun, J. D.; Santiago, P.; Laihsu, A.; Kimura, N.; Yamanaka, A.; Bersot, R.; Humphries, P. S.

10.1101/234765 — neuroscience — Posted on 2018-02-02

1647 Neural substrates of navigational decision-making in Drosophila larva anemotaxis

Jovanic, T.; Truman, J. W.; Gershow, M.; Zlatic, M.

10.1101/244608 — neuroscience — Posted on 2018-02-02

1648 Circuit and cellular mechanisms facilitate the transformation from dense to sparse coding in the insect olfactory system

Betkiewicz, R. L.; Nawrot, M. P.; Lindner, B.

10.1101/240671 — neuroscience — Posted on 2018-02-02

1649 Transcription-dependent DNA methylation at the imprinted Zrsr1-DMR

Joh, K.

10.1101/249524 — molecular biology — Posted on 2018-02-02

1650 Genomes of trombidid mites reveal novel predicted allergens and laterally-transferred genes associated with secondary metabolism

Dong, X.; Chaisiri, K.; Xia, D.; Armstrong, S. D.; Fang, Y.; Donnelly, M. J.; Kadowaki, T.; McGarry, J. W.; Darby, A. C.; Makepeace, B. L.

10.1101/259044 — genomics — Posted on 2018-02-02

1651 Mitochondrial D-loop DNA analyses of Norway Lobster (Nephrops norvegicus) reveals genetic isolation between Atlantic and Mediterranean populations

Gallagher, J.; Finarelli, J. A.; Jonasson, J. P.; Carlsson, J.

10.1101/258392 — genetics — Posted on 2018-02-02

1652 Bacterial adaptation to diet is a key evolutionary force shaping Drosophila-Lactobacillus symbiosis

Martino, M. E.; Joncour, P.; Leenay, R.; Gervais, H.; Shah, M.; Hughes, S.; Gillet, B.; Beisel, C.; Leulier, F.

10.1101/222364 — evolutionary biology — Posted on 2018-02-02

1653 Genome-wide transcriptome analysis identifies alternative splicing regulatory network and key splicing factors in mouse and human psoriasis

Li, J.; Yu, P.

10.1101/259291 — bioinformatics — Posted on 2018-02-02

1654 Two parallel pathways implement robust propionate catabolism and detoxification in mycobacteria

Tummler, K.; Zimmermann, M.; Schubert, O. T.; Aebersold, R.; Kühn, C.; Sauer, U.; Klipp, E.

10.1101/258947 — systems biology — Posted on 2018-02-02

1655 Discovery and Evaluation of Biosynthetic Pathways for the Production of Five Methyl Ethyl Ketone Precursors

Tokic, M.; Hadadi, N.; Ataman, M.; Neves, D. S.; Ebert, B. E.; Blank, L. M.; Miskovic, L.; Hatzimanikatis, V.

10.1101/209569 — synthetic biology — Posted on 2018-02-02

1656 MiR-21 Regulates Metabolic Adaptation of TH17 Cells during Autoimmunity and Host Defence

Yu, X.; Wang, L.; Yao, C.; Qiu, R.; Cui, Y. G.; Dai, D.; Deng, J.; Hou, G. J.; Wang, Y.; Qian, J.; Ouyang, Y.; Qin, Y. T.; Qu, B.; Zhou, H. B.; Qian, Y. C.; Tang, Y. J.; Shen, N.

10.1101/218545 — immunology — Posted on 2018-02-02

1657 Investigation Of Gluthatione S-Transferase Variants In A Healht Population In Goiania-Go

Pereira, L. C. G.; Bergamo, N. A.; Reis, A. A. d. S.; Anunciacao, C. E.; Silveira-Lacerda, E. d. P.

10.1101/258806 — genetics — Posted on 2018-02-02

1658 Paternal germ line aging: DNA methylation age prediction from human sperm

Jenkins, T. G.; Aston, K. I.; Smith, A. D.; Carrell, D. T.

10.1101/220764 — genetics — Posted on 2018-02-02

1659 Evolution of human, chicken, alligator, frog and zebrafish mineralocorticoid receptors: Allosteric influence on steroid specificity

Katsu, Y.; Oka, K.; Baker, M. E.

10.1101/151233 — evolutionary biology — Posted on 2018-02-02

1660 Methods in Description and Validation of Local Metagenetic Microbial Communities

Molik, D. C.; Pfrender, M.; Emrich, S.

10.1101/198614 — bioinformatics — Posted on 2018-02-02

1661 Ethology as a physical science

Brown, A. E.; de Bivort, B.

10.1101/220855 — animal behavior and cognition — Posted on 2018-02-02

1662 Blue light advances bud burst in branches of three temperate deciduous tree species under short-day conditions

Brelsford, C. C.; Robson, T. M.

10.1101/259101 — plant biology — Posted on 2018-02-02

1663 Gallic Acid Disrupts Aβ1-42 Aggregation and Rescues Cognitive Decline of APP/PS1 Transgenic Mouse

Yu, M.; Chen, X.; Liu, J.; Ma, Q.; Chen, H.; Zhou, L.; Yang, S.; Zheng, L.; Ning, C.; Gao, T.; Xu, J.; Hou, S.-T.

10.1101/258848 — neuroscience — Posted on 2018-02-02

1664 Single cell network analysis with a mixture of Nested Effects Models

Pirkl, M.; Beerenwinkel, N.

10.1101/258202 — systems biology — Posted on 2018-02-02

1665 Causal interactions from proteomic profiles: molecular data meets pathway knowledge

Babur, O.; Luna, A.; Korkut, A.; Durupinar, F.; Siper, M. C.; Dogrusoz, U.; Aslan, J. E.; Sander, C.; Demir, E.

10.1101/258855 — systems biology — Posted on 2018-02-02

1666 Mathematical Modelling of Actin treadmill in Apicomplexans

Prajapat, M. K.; Pathak, S.; Gauba, R.; Kale, A.; Saini, S.

10.1101/258913 — systems biology — Posted on 2018-02-02

1667 Addressing the Most Neglected Diseases through an Open Research Model: the Discovery of Fenarimols as Novel Drug Candidates for Eumycetoma

Lim, W.; Melse, Y.; Konings, M.; Duong, H. P.; Eadie, K.; Laleu, B.; Perry, B.; Todd, M.; Ioset, J.-R.; van de Sande, W.

10.1101/258905 — pharmacology and toxicology — Posted on 2018-02-02

1668 Specific octopaminergic neurons arbitrate between perseverance and reward in hungry Drosophila

Sayin, S.; De Backer, J.-F.; Wosniack, M. E.; Lewis, L.; Siju, K. P.; Frisch, L.-M.; Gjorgjieva, J.; Grunwald Kadow, I.

10.1101/259119 — neuroscience — Posted on 2018-02-02

1669 Early candidate urine biomarkers for detecting Alzheimer’s disease before beta amyloid plaque deposition in an APP (swe)/PSEN1dE9 transgenic mouse model

Zhang, F.; Wei, J.; Li, X.; Ma, C.; Gao, Y.

10.1101/258921 — molecular biology — Posted on 2018-02-02

1670 Evidence of independent acquisition and adaption of ultra-small bacteria to human hosts across the highly diverse yet reduced genomes of the phylum Saccharibacteria

McLean, J. S.; Bor, B.; To, T. T.; Liu, Q.; Kearns, K. A.; Solden, L. M.; Wrighton, K. C.; He, X.; Shi, W.

10.1101/258137 — microbiology — Posted on 2018-02-02

1671 Mutational origins and pathogenic consequences of multinucleotide mutations in 6,688 trios with developmental disorders

Kaplanis, J.; Akawi, N.; Gallone, G.; McRae, J. F.; Prigmore, E.; Wright, C. F.; Fitzpatrick, D. R.; Firth, H. V.; Barrett, J. C.; Hurles, M. E.; on behalf of the Deciphering Developmental Disorders Study,

10.1101/258723 — genomics — Posted on 2018-02-02

1672 Haplotypes associated to gene expression in breast cancer: can they lead us to the susceptibility markers?

Edvardsen, H.; Kulle, B.; Tsalenko, A.; Grenaker Alnaes, G. I.; Ekeberg Johansen, F.; Enerly, E.; Vailaya, A.; Lonning, P.-E.; Helland, A.; Syvanen, A.-C.; Yakhini, Z.; Borresen-Dale, A.-L.; Frigessi, A.; Kristensen, V. N.

10.1101/248047 — genomics — Posted on 2018-02-02

1673 Assessing the impact of high-throughput sequencing strategy and model complexity on ABC-inferred demographic history in mussels

Fraisse, C.; Roux, C.; Gagnaire, P.-A.; Romiguier, J.; Faivre, N.; Welch, J. J.; Bierne, N.

10.1101/259135 — evolutionary biology — Posted on 2018-02-02

1674 Zebrafish sp7 mutants show tooth cycling independent of attachment, eruption and poor differentiation of teeth

Kague, E.; Witten, P. E.; Soenens, M.; Campos, C. L.; Lubiana, T.; Fisher, S.; Hammond, C.; Robson Brown, K.; Passos Bueno, M. R.; Huysseune, A.

10.1101/259085 — developmental biology — Posted on 2018-02-02

1675 Modeling polypharmacy side effects with graph convolutional networks

Zitnik, M.; Agrawal, M.; Leskovec, J.

10.1101/258814 — bioinformatics — Posted on 2018-02-02

1676 Proteomics as a metrological tool to evaluate genome annotation accuracy following de novo genome assembly: a case study using the Atlantic bottlenose dolphin (Tursiops truncatus)

Neely, B. A.; Ellisor, D. L.; Davis, W. C.

10.1101/254250 — bioinformatics — Posted on 2018-02-02

1677 Rapid multi-locus sequence typing direct from uncorrected long reads using Krocus

Page, A.; Keane, J.

10.1101/259150 — bioinformatics — Posted on 2018-02-02

1678 BDQC: a general-purpose analytics tool for domain-blind validation of Big Data

Deutsch, E.; Kramer, R.; Ames, J.; Bauman, A.; Campbell, D. S.; Chard, K.; Clark, K.; D'Arcy, M.; Dinov, I.; Donovan, R.; Foster, I.; Heavner, B. D.; Hood, L. E.; Kesselman, C.; Madduri, R.; Mi, H.; Muruganujan, A.; Pa, J.; Price, N. D.; Robinson, M.; Sepehrband, F.; Toga, A. W.; Van Horn, J. D.; Zhao, L.; Glusman, G.

10.1101/258822 — bioinformatics — Posted on 2018-02-02

1679 Comprehensive and empirical evaluation of machine learning algorithms for LC retention time prediction

Bouwmeester, R.; Martens, L.; Degroeve, S.

10.1101/259168 — bioinformatics — Posted on 2018-02-02

1680 Divergent PAM Specificity of a Highly-Similar SpCas9 Ortholog

Chatterjee, P.; Jakimo, N.; Jacobson, J. M.

10.1101/258939 — microbiology — Posted on 2018-02-02

1681 Biological and clinical insights from genetics of insomnia symptoms

Lane, J. M.; Jones, S.; Dashti, H.; Wood, A.; Aragam, K.; van Hees, V. T.; Brumpton, B.; Winsvold, B. S.; Wang, H.; Bowden, J.; Song, Y.; Patel, K.; Anderson, S. G.; Beaumont, R.; Bechtold, D. A.; Cade, B.; Kathiresan, S.; Little, M. A.; Luik, A. I. I.; Loudon, A. S.; Purcell, S.; Richmond, R. C.; Scheer, F. A.; Tyrrell, J.; Winkelman, J.; HUNT All In Sleep, ; Strand, L. B.; Nielsen, J. B.; Willer, C. J.; Redline, S.; Spiegelhalder, K.; Kyle, S. D.; Ray, D. W.; Zwart, J. A.; Hveem, K.; Frayling, T. M.; Lawlor, D. A.; Rutter, M. K.; Weedon, M. N.; Saxena, R.

10.1101/257956 — genomics — Posted on 2018-02-02

1682 Mitochondrial D-loop DNA analyses of Norway Lobster (Nephrops norvegicus) reveals genetic isolation between Atlantic and Mediterranean populations

Gallagher, J.; Finarelli, J. A.; Jonasson, J. P.; Carlsson, J.

10.1101/258392 — genetics — Posted on 2018-02-02

1683 Single-cell analysis of progenitor cell dynamics and lineage specification of the human fetal kidney

Menon, R.; Otto, E. A.; Kokoruda, A.; Zhou, J.; Zhang, Z.; Yoon, E.; Chen, Y.-C.; Troyanscaya, O.; Spence, J.; Kretzler, M.; Cebrian, C.

10.1101/258798 — developmental biology — Posted on 2018-02-01

1684 Activity of Antimicrobial Peptides Decreases with Increased Cell Membrane Crossing Free Energy Cost

Zou, R.; Zhu, X.; Tu, Y.; Wu, J.; Landry, M. P.

10.1101/258863 — biophysics — Posted on 2018-02-01

1685 Automated Antibody Characterization and Screening for Array Tomography via Probabilistic Synapse Detection

Simhal, A. K.; Gong, B.; Trimmer, J. S.; Weinberg, R. J.; Smith, S. J.; Sapiro, G.; Micheva, K. D.

10.1101/258756 — neuroscience — Posted on 2018-02-01

1686 Perceived timing of active head movement at different speeds

Sachgau, C.; Chung, W.; Barnett-Cowan, M.

10.1101/258590 — neuroscience — Posted on 2018-02-01

1687 Titer estimation for quality control (TEQC) method: a practical approach for optimal production of protein complexes using the baculovirus expression vector system

Imasaki, T.; Wenzel, S.; Yamada, K.; Bryant, M.; Takagi, Y.

10.1101/258624 — molecular biology — Posted on 2018-02-01

1688 Candida albicans dispersed cells signify a developmental state distinct from biofilm and planktonic phases

Uppuluri, P.; Acosta Zakvidar, M.; Anderson, M.; Dunn, M.; Berman, J.; Lopez Ribot, J. L.; Koehler, J.

10.1101/258608 — microbiology — Posted on 2018-02-01

1689 CNBP controls c-Rel dependent IL-12 β gene transcription and Th1 immunity

Chen, Y.; Sharma, S.; Assis, P. A.; Jiang, Z.; Olive, A. J.; Hang, S.; Bernier, J.; Huh, J. R.; Sassetti, C. M.; Knipe, D. M.; Gazzinelli, R. T.; Fitzgerald, K. A.

10.1101/258731 — immunology — Posted on 2018-02-01

1690 Sequencing Metrics of Human Genomes Extracted from Single Cancer Cells Individually Isolated in a Valveless Microfluidic Device

Marie, R.; Podenphant, M.; Koprowska, K.; Baerlocher, L.; Vulders, R. C.; Wilding, J.; Ashley, N.; McGowan, S. J.; van Strijp, D.; van Hemert, F.; Olesen, T.; Agersnap, N.; Bilenberg, B.; Sabatel, C.; Schira, J.; Kristensen, A.; Bodmer, W.; van der Zaag, P. J.; Mir, K. U.

10.1101/258780 — genomics — Posted on 2018-02-01

1691 Hybridization and rampant mitochondrial introgression among fire salamanders in peninsular Italy

Bisconti, R.; Porretta, D.; Arduino, P.; Nascetti, G.; Canestrelli, D.

10.1101/258541 — evolutionary biology — Posted on 2018-02-01

1692 Shugoshin is essential for meiotic prophase checkpoints in C. elegans

Bohr, T.; Nelson, C. R.; Giacopazzi, S.; Lamelza, P.; Bhalla, N.

10.1101/258830 — cell biology — Posted on 2018-02-01

1693 SeqOthello: Query over RNA-seq experiments at scale

Yu, Y.; Liu, J.; Liu, X.; Zhang, Y.; Magner, E.; Qian, C.; Liu, J.

10.1101/258772 — bioinformatics — Posted on 2018-02-01

1694 Deterministic response strategies in trial-and-error learning

Mohr, H.; Zwosta, K.; Markovic, D.; Bitzer, S.; Wolfensteller, U.; Ruge, H.

10.1101/258459 — animal behavior and cognition — Posted on 2018-02-01

1695 Connecting conceptual and spatial search via a model of generalization

Wu, C. M.; Schulz, E.; Garvert, M. M.; Meder, B.; Schuck, N. W.

10.1101/258665 — animal behavior and cognition — Posted on 2018-02-01

1696 Sharing is not erring: Pseudo-reciprocity in collective search

Bouhlel, I.; Wu, C. M.; Hanaki, N.; Goldstone, R. L.

10.1101/258715 — animal behavior and cognition — Posted on 2018-02-01

1697 Impaired Spatial Reorientation in the 3xTg-AD Mouse Model of Alzheimer’s Disease

Stimmell, A.; Baglietto-Vargas, D.; Moseley, S. C.; Lapointe, V.; LaFerla, F. M.; McNaughton, B. L.; Wilber, A. A.

10.1101/258616 — neuroscience — Posted on 2018-02-01

1698 Type-I interferons inhibit interleukin-10 signaling and favor type 1 diabetes development in NOD mice

Iglesias, M.; Arun, A.; Chicco, M.; Lam, B.; Talbot, C.; Ivanova, V.; Lee, W. P. A.; Brandacher, G.; Raimondi, G.

10.1101/258525 — immunology — Posted on 2018-02-01

1699 Robustness of Transposable Element regulation but no genomic shock observed in interspecific Arabidopsis hybrids

Goebel, U.; Arce, A.; He, F.; Rico, A.; Schmitz, G.; de Meaux, J.

10.1101/258467 — genomics — Posted on 2018-02-01

1700 Targeted enrichment outperforms other enrichment techniques and enables more multi-species RNA-Seq analyses

Chung, M.; Teigen, L.; Liu, H.; Libro, S.; Shetty, A.; Kumar, N.; Zhao, X.; Bromley, R.; Tallon, L. J.; Sadzewicz, L.; Fraser, C. M.; Rasko, D.; Filler, S.; Foster, J.; Michalski, M.; Bruno, V.; Dunning Hotopp, J.

10.1101/258640 — genomics — Posted on 2018-02-01

1701 Bioelectric-calcineurin signaling module regulates allometric growth and size of the zebrafish fin

Daane, J.; Lanni, J.; Rothenberg, I.; Seebohm, G.; Higdon, C.; Johnson, S.; Harris, M.

10.1101/258442 — developmental biology — Posted on 2018-02-01

1702 AAK1 inhibits WNT signaling by promoting clathrin-mediated endocytosis of LRP6

Agajanian, M.; Walker, M.; Axtman, A.; Ruela-de-Sousa, R.; Rabinowitz, A.; Graham, D.; Ryan, M.; Serafin, S.; Bennett, J.; Counago, R.; Drewry, D.; Elkins, J.; Gileadi, C.; Gileadi, O.; Godoi, P.; Kapadia, N.; Muller, S.; Santiago, A.; Sorrell, F.; Wells, C.; Fedorov, O.; Willson, T.; Zuercher, W.; Major, M. B.

10.1101/258632 — cell biology — Posted on 2018-02-01

1703 A hypomorphic Stip1 allele reveals the requirement for chaperone networks in mouse development and aging

Lackie, R.; Lopes, M. H.; Farhan, S. M. K.; Razzaq, A.; Moshitzky, G.; Prado, M. B.; Beraldo, F. H.; Maciejewski, A.; Gros, R.; Fan, J.; Choy, W.-Y.; Greenberg, D.; Martins, V. R.; Duennwald, M.; Soreq, H.; Prado, V. F.; Prado, M. A. M.

10.1101/258673 — cell biology — Posted on 2018-02-01

1704 Random forest based similarity learning for single cell RNA sequencing data

Baran Pouyan, M.; Kostka, D.

10.1101/258699 — bioinformatics — Posted on 2018-02-01

1705 Identification of transcriptional signatures for cell types from single-cell RNA-Seq

Ntranos, V.; Yi, L.; Melsted, P.; Pachter, L.

10.1101/258566 — bioinformatics — Posted on 2018-02-01

1706 Estimating sleep parameters using an accelerometer without sleep diary

van Hees, V. T.; Sabia, S.; Jones, S. E.; Wood, A. R.; Anderson, K. N.; Kivimaki, M.; Frayling, T. M.; Pack, A. I.; Bucan, M.; Mazzotti, D. R.; Gehrman, P. R.; Singh-Manoux, A.; Weedon, M. N.

10.1101/257972 — epidemiology — Posted on 2018-02-01

1707 Single Session Real-time fMRI Neurofeedback has a Lasting Impact on Cognitive Behavioral Therapy Strategies

MacDuffie, K. E.; MacInnes, J.; Dickerson, K. C.; Eddington, K. M.; Strauman, T. J.; Adcock, R. A.

10.1101/258095 — neuroscience — Posted on 2018-02-01

1708 Rbfox splicing factors maintain skeletal muscle mass by regulating calpain3 and proteostasis

Singh, R. K.; Kolonin, A. M.; Fiorotto, M. L.; Cooper, T. A.

10.1101/257261 — molecular biology — Posted on 2018-02-01

1709 Frequent variants in the Japanese population determine quasi-Mendelian inheritance of rare retinal ciliopathy

Nikopoulos, K.; Cisarova, K.; Koskiniemi-Kuendig, H.; Miyake, N.; Farinelli, P.; Quinodoz, M.; Imran, M.; Prunotto, A.; Akiyama, M.; Kamatani, Y.; Terao, C.; Miya, F.; Ikeda, Y.; Ueno, S.; Fuse, N.; Murakami, A.; Terasaki, H.; Sonoda, K.-H.; Ishibashi, T.; Kubo, M.; Cremers, F. P. M.; Matsumoto, N.; Nishiguchi, K. M.; Nakazawa, T.; Rivolta, C.

10.1101/257634 — genomics — Posted on 2018-02-01

1710 An Algorithmic Information Calculus for Causal Discovery and Reprogramming Systems

Zenil, H.; Kiani, N. A.; Marabita, F.; Deng, Y.; Elias, S.; Schmidt, A.; Ball, G.; Tegner, J.

10.1101/185637 — systems biology — Posted on 2018-02-01

1711 Kinetics of winter deacclimation in response to temperature determines dormancy status and quantifies chilling requirement in grapevines (Vitis spp.)

Kovaleski, A. P.; Reisch, B. I.; Londo, J. P.

10.1101/256362 — plant biology — Posted on 2018-02-01

1712 NFTsim: Theory and Simulation of Multiscale Neural Field Dynamics

Sanz-Leon, P.; Robinson, P. A.; Knock, S. A.; Drysdale, P. D.; Abeysuriya, R. G.; Fung, P. K.; Rennie, C. J.; Zhao, X.

10.1101/237032 — neuroscience — Posted on 2018-02-01

1713 KLF6 and STAT3 co-occupy regulatory DNA and functionally synergize to promote axon growth in CNS neurons

Wang, Z.; Venkatesh, I.; Mehra, V.; Simpson, M.; Maunze, B.; Eastwood, E.; Holan, L.; Blackmore, M.

10.1101/257022 — neuroscience — Posted on 2018-02-01

1714 Genome-wide Analysis of Insomnia (N=1,331,010) Identifies Novel Loci and Functional Pathways

Jansen, P. R.; Watanabe, K.; Stringer, S.; Skene, N.; Bryois, J.; Hammerschlag, A. R.; de Leeuw, C. A.; Benjamins, J.; Munoz-Manchado, A. B.; Nagel, M.; Savage, J. E.; Tiemeier, H.; White, T.; Tung, J. Y.; Hinds, D. A.; Vacic, V.; Sullivan, P. F.; van der Sluis, S.; Polderman, T. J.; Smit, A. B.; Hjerling-Leffler, J.; van Someren, E. J.; Posthuma, D.

10.1101/214973 — genetics — Posted on 2018-02-01

1715 Bacterial adaptation to host diet is a key evolutionary force shaping host-microbe symbiosis

Martino, M. E.; Joncour, P.; Leenay, R.; Gervais, H.; Shah, M.; Hughes, S.; Gillet, B.; Beisel, C.; Leulier, F.

10.1101/222364 — evolutionary biology — Posted on 2018-02-01

1716 Dynein-2 intermediate chains play crucial but distinct roles in primary cilia formation and function

Vuolo, L.; Stevenson, N. L.; Heesom, K.; Stephens, D. J.

10.1101/251694 — cell biology — Posted on 2018-02-01

1717 Detection of complex structural variation from paired-end sequencing data

Arthur, J. G.; Chen, X.; Zhou, B.; Urban, A. E.; Wong, W. H.

10.1101/200170 — bioinformatics — Posted on 2018-02-01

1718 Label-free assessment of red blood cell storage lesions by deep learning

Doan, M.; Sebastian, J. A.; Pinto, R. N.; McQuin, C.; Goodman, A.; Wolkenhauer, O.; Parsons, M. J.; Acker, J. P.; Rees, P.; Hennig, H.; Kolios, M. C.; Carpenter, A. E.

10.1101/256180 — bioinformatics — Posted on 2018-02-01

1719 clusterProfiler: An universal enrichment tool for functional and comparative study

Yu, G.

10.1101/256784 — bioinformatics — Posted on 2018-02-01

1720 Ferrous iron mediates translation

Bray, M. S.; Bowman, J. C.; Petrov, A. S.; Reddi, A. R.; Williams, L. D.; Glass, J. B.

10.1101/256958 — biochemistry — Posted on 2018-02-01

1721 Differences in firing efficiency, chromatin and transcription underlie the developmental plasticity of Arabidopsis originome

Sequeira-Mendes, J.; Vergara, Z.; Peiro, R.; Morata, J.; Araguez, I.; Costas, C.; Mendez-Giraldez, R.; Casacuberta, J.; Bastolla, U.; Gutierrez, C.

10.1101/258301 — plant biology — Posted on 2018-02-01

1722 Dissection of the microProtein miP1 floral repressor complex in Arabidopsis

Rodrigues, V. L.; Dolde, U.; Straub, D.; Eguen, T.; Botterweg-Paredes, E.; Sun, B.; Hong, S.; Graeff, M.; Li, M.-W.; Gendron, J.; Wenkel, S.

10.1101/258228 — plant biology — Posted on 2018-02-01

1723 Longitudinal development of hippocampal subregions from childhood to adulthood

Tamnes, C. K.; Bos, M. G. N.; van de Kamp, F. C.; Peters, S.; Crone, E. A.

10.1101/186270 — neuroscience — Posted on 2018-02-01

1724 Surprise About Sensory Event Timing Drives Cortical Transients in the Beta Frequency Band

Meindertsma, T.; Kloosterman, N. A.; Engel, A. K.; Wagenmakers, E.-J.; Donner, T. H.

10.1101/254060 — neuroscience — Posted on 2018-02-01

1725 Presenilin-mediated cleavage of APP regulates synaptotagmin-7 and presynaptic plasticity

Barthet, G.; Jorda-Siquier, T.; Ruli-Masante, J.; Bernadou, F.; Mueller, U.; Mulle, C.

10.1101/258335 — neuroscience — Posted on 2018-02-01

1726 Rare variants in the genetic background modulate the expressivity of neurodevelopmental disorders

Pizzo, L.; Jensen, M.; Polyak, A.; Rosenfeld, J. A.; Mannik, K.; Krishnan, A.; McCready, E.; Pichon, O.; Le Caignec, C.; Van Dijck, A.; Pope, K.; Voorhoeve, E.; Yoon, J.; Stankiewicz, P.; Cheung, S. W.; Pazuchanics, D.; Huber, E.; Kumar, V.; Kember, R.; Mari, F.; Curro, A.; Castiglia, L.; Galesi, O.; Avola, E.; Mattina, T.; Fichera, M.; Mandara, L.; Vincent, M.; Nizon, M.; Mercier, S.; Beneteau, C.; Blesson, S.; Martin-Coignard, D.; Mosca-Boidron, A.-L.; Caberg, J. H.; Bucan, M.; Zeesman, S.; Nowaczyk, M. J. M.; Lefebvre, M.; Faivre, L.; Callier, P.; Skinner, C.; Keren, B.; Perrine, C.; Pronte

10.1101/257758 — genomics — Posted on 2018-02-01

1727 Identification of candidate genes for gelatinization temperature, gel consistency and pericarp color by GWAS in rice based on SLAF-sequencing

Yang, x.; Xia, X.; Zeng, Y.; Nong, B.; Zhang, Z.; Wu, Y.; Xiong, F.; Zhang, Y.; Liang, H.; Deng, G.; Li, D.

10.1101/258244 — genomics — Posted on 2018-02-01

1728 Germline DNA replication timing shapes mammalian genome composition

Yehida, Y.; Blumenfeld, B.; Mayorek, N.; Makedonski, K.; Vardi, O.; Mansour, Y.; Masika, H.; Farago, M.; Baror-Sebban, S.; Buganim, Y.; Koren, A.; Simon, I.

10.1101/258426 — genomics — Posted on 2018-02-01

1729 Computational Chromosome Conformation Capture by Correlation of ChIP-seq at CTCF motifs

Ibn-Salem, J.; Andrade-Navarro, M. A.

10.1101/257584 — genomics — Posted on 2018-02-01

1730 Local and global chromatin interactions are altered by large genomic deletions associated with human brain development

Zhang, X.; Zhang, Y.; Zhu, X.; Purmann, C.; Haney, M.; Ward, T.; Yao, J.; Weissman, S.; Urban, A.

10.1101/182451 — genetics — Posted on 2018-02-01

1731 Evidence for genetic correlations and bidirectional, causal effects between smoking and sleep behaviours

Gibson, M.; Munafo, M. R.; Taylor, A.; Treur, J. L.

10.1101/258384 — genetics — Posted on 2018-02-01

1732 A simple genetic basis for managing maternally transmitted symbionts

Funkhouser-Jones, L. J.; van Opstal, E. J.; Sharma, A.; Bordenstein, S. R.

10.1101/256909 — evolutionary biology — Posted on 2018-02-01

1733 Neuregulin-1 exerts molecular control over axolotl lung regeneration through ErbB family receptors

Jensen, T. B.; Giunta, P.; Schulz, N. G.; Kyeremateng, Y.; Wong, H.; Adesina, A.; Monaghan, J. R.

10.1101/258517 — developmental biology — Posted on 2018-02-01

1734 GEMC1 and CCNO are required for efferent duct development and male fertility

Terre, B.; Lewis, M.; Gil-Gomez, G.; Stracker, T. H.

10.1101/258418 — developmental biology — Posted on 2018-02-01

1735 Tetracyclines Modify Translation By Targeting Key Human rRNA Substructures.

Mortison, J. D.; Schenone, M.; Myers, J. A.; Zhang, Z.; Chen, L.; Ciarlo, C.; Comer, E.; Natchiar, S. K.; Carr, S. A.; Klaholz, B. P.; Myers, A. G.

10.1101/256230 — cell biology — Posted on 2018-02-01

1736 Selection dynamics in transient compartmentalization

Blokhuis, A. W. P.; Lacoste, D.; Nghe, P.; Peliti, L.

10.1101/258269 — biophysics — Posted on 2018-02-01

1737 Solubilization kinetics determines the pulsatory dynamics of lipid vesicles exposed to surfactant

Chabanon, M.; Rangamani, P.

10.1101/225946 — biophysics — Posted on 2018-02-01

1738 Improved pathway reconstruction from RNA interference screens by exploiting off-target effects

Srivatsa, S.; Kuipers, J.; Schmich, F.; Eicher, S.; Emmenlauer, M.; Dehio, C.; Beerenwinkel, N.

10.1101/258319 — bioinformatics — Posted on 2018-02-01

1739 Allele-specific transcription factor binding as a benchmark for assessing variant impact predictors

Wagih, O.; Merico, D.; Delong, A.; Frey, B. J.

10.1101/253427 — bioinformatics — Posted on 2018-02-01

1740 Greater range filling can explain why evolutionarily older and slower diversifying plants are less threatened by extinction

Tanentzap, A. J.; Igea, J.; Johnston, M. G.; Larcombe, M. J.

10.1101/152215 — evolutionary biology — Posted on 2018-02-01

1741 Horizontal gene transfer constrains the timing of methanogen evolution

Wolfe, J. M.; Fournier, G. P.

10.1101/129494 — evolutionary biology — Posted on 2018-02-01

1742 Drosophila CaV2 Channels Harboring Human Migraine Mutations Cause Synapse Hyperexcitability That Can Be Suppressed By Inhibition Of A Ca2+ Store Release Pathway

Brusich, D. J.; Spring, A. M.; James, T. D.; Yeates, C. J.; Helms, T. H.; Frank, C. A.

10.1101/141366 — neuroscience — Posted on 2018-02-01

1743 Fatherhood alters gene expression within the MPOA

Seelke, A. M. H.; Bond, J. M.; Simmons, T. C.; Stolzenberg, D.; Rhemtulla, M.; Bales, K. L.

10.1101/258111 — neuroscience — Posted on 2018-02-01

1744 Peroxiredoxin-mediated HMGB1 oxidation and secretion in response to inflammatory stimuli

Kwak, M. S.; Kim, H. S.; Lkhamsuren, K.; Kim, Y. H.; Hahn, M. G.; Shin, J. M.; Park, I. H.; Lee, S. K.; Rhee, S. G.; Shin, J.-S.

10.1101/258285 — immunology — Posted on 2018-02-01

1745 A Comprehensive Overview Of Genomic Imprinting In Breast & Its Deregulation In Cancer

Goovaerts, T.; Steyaert, S.; Vandenbussche, C. A.; Galle, J.; Thas, O.; Van Criekinge, W.; De Meyer, T.

10.1101/257824 — cancer biology — Posted on 2018-02-01

1746 Identification of endogenous Adenomatous polyposis coli interaction partners and β-catenin-independent targets by proteomics

Popow, O.; Tatham, M.; Paulo, J.; Rojaa, A.; Loyer, N.; Newton, I. P.; Januschke, J.; Haigis, K.; Nathke, I.

10.1101/258400 — cancer biology — Posted on 2018-02-01

1747 Report of Partial findings from the National Toxicology Program Carcinogenesis Studies of Cell Phone Radiofrequency Radiation in Hsd: Sprague Dawley(R) SD rats (Whole Body Exposure)

Wyde, M.; Cesta, M.; Blystone, C.; Elmore, S.; Foster, P.; Hooth, M.; Kissling, G.; Malarkey, D.; Sills, R.; Stout, M.; Walker, N.; Witt, K.; Wolfe, M.; Bucher, J.

10.1101/055699 — cancer biology — Posted on 2018-02-01

1748 Structure of Zip2:Spo16, a conserved XPF:ERCC1-like complex critical for meiotic crossover formation

Arora, K.; Corbett, K. D.

10.1101/258194 — biochemistry — Posted on 2018-02-01

1749 PTMscape: an open source tool to predict generic post-translational modifications and map hotspots of modification crosstalk

Li, G. X.; Vogel, C.; Choi, H.

10.1101/257386 — bioinformatics — Posted on 2018-02-01

1750 Regulation by competition: a hidden layer of gene regulatory network

Yuan, Y.; Wei, L.; Hu, T.; Li, S.; Cheng, T.; Lei, J.; Xie, Z.; Zhang, M. Q.; Wang, X.

10.1101/258129 — systems biology — Posted on 2018-02-01

1751 Functional organization of motion and disparity sensitivity in human visual cortex

Kohler, P. J.; Meredith, W.; Norcia, A. M.

10.1101/250878 — neuroscience — Posted on 2018-02-01

1752 Single Session Real-time fMRI Neurofeedback has a Lasting Impact on Cognitive Behavioral Therapy Strategies

MacDuffie, K. E.; MacInness, J.; Dickerson, K. C.; Eddington, K. M.; Strauman, T. J.; Adcock, R. A.

10.1101/258095 — neuroscience — Posted on 2018-02-01

1753 Habitat loss is information loss: Species distribution models are compromised in anthropogenic landscapes

Dinnage, R.; Cardillo, M.

10.1101/258038 — ecology — Posted on 2018-02-01

1754 DeepHINT: Understanding HIV-1 integration via deep learning with attention

Hu, H.; Xiao, A.; Zhang, S.; Li, Y.; Shi, X.; Jiang, T.; Zhang, L.; Zhang, L.; Zeng, J.

10.1101/258152 — bioinformatics — Posted on 2018-02-01

1755 Analysis of global and site-specific radiation damage in cryo-EM

Hattne, J.; Shi, D.; Glynn, C.; Zee, C.-T.; Gallagher-Jones, M.; Martynowycz, M.; Rodriguez, J.; Gonen, T.

10.1101/258178 — biochemistry — Posted on 2018-02-01

Archive, 2018-02