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Archive, 2024-07

3 A subset of brain regions within adult functional connectivity networks demonstrate high reliability across early development
Tu, J. C.; Wang, Y.; Wang, X.; Dierker, D.; Sobolewski, C. M.; Day, T. K. M.; Kardan, O.; Miranda Dominguez, O.; Moore, L. A.; Elison, J. T.; Gordon, E. M.; Laumann, T. O.; Eggebrecht, A. T.; Wheelock, M. D.
10.1101/2024.07.31.606025 — neuroscience — Posted on 2024-07-31
6 The progression of neurovascular features and chemokine signatures of the intervertebral disc with degeneration
Walk, R.; Broz, K.; Jing, L.; Potter, R.; Gonzalez, C. E.; Beeve, A.; Scheller, E.; Gupta, M.; Setton, L.; Tang, S. Y.
10.1101/2024.07.12.603182 — bioengineering — Posted on 2024-07-31
11 BMP9 and BMP10 coordinate liver cellular crosstalk to maintain liver health
Zhao, D.; Huang, Z.; Li, X.; Wang, H.; Hou, Q.; Wang, Y.; Yan, F.; Yang, W.; Liu, D.; Yi, S.; Han, C.; Hao, Y.; Tang, L.
10.1101/2024.02.08.579542 — cell biology — Posted on 2024-07-31
12 Model-driven engineering of Yarrowia lipolytica for improved microbial oil production
Duman-Özdamar, Z. E.; Julsing, M. K.; Martins dos Santos, V. A. P.; Hugenholtz, J.; Suarez-Diez, M.
10.1101/2024.07.31.606002 — molecular biology — Posted on 2024-07-31
13 DNA-enhanced CuAAC ligand enables live-cell detection of intracellular biomolecules
Nian, K.; Liu, Y.; Qiu, Y.; Zhang, Z.; Brigandi, L.; Wanunu, M.; Rouhanifard, S. H.
10.1101/2022.11.10.515969 — molecular biology — Posted on 2024-07-31
15 Deep mutational scanning of H5 hemagglutinin to inform influenza virus surveillance
Dadonaite, B.; Ahn, J. J.; Ort, J. T.; Yu, J.; Furey, C.; Dosey, A.; Hannon, W. W.; Baker, A. V.; Webby, R. J.; King, N. P.; Liu, Y.; Hensley, S. E.; Peacock, T. P.; Moncla, L. H.; Bloom, J. D.
10.1101/2024.05.23.595634 — microbiology — Posted on 2024-07-31
16 IFNB induced by non-lytic virus immunotherapy promotes improved survival in hepatocellular carcinoma, mediated by MHCII-independent cytotoxic CD4+ T-cells
Hughes, R.; Moran, A.; Scott, K. J.; Appleton, E.; Bentham, M. J.; Ilett, E.; Melcher, A.; Macdonald, A.; Samson, A.; Griffin, S.
10.1101/2024.02.23.581738 — immunology — Posted on 2024-07-31
18 T cells promote distinct transcriptional programs of cutaneous inflammatory disease in human skin structural cells
DeBerg, H. A.; Fahning, M. L.; Schlenker, J. D.; Schmitt, W. P.; Gratz, I. K.; Carlin, J. S.; Campbell, D. J.; Morawski, P. A.
10.1101/2024.07.31.606077 — immunology — Posted on 2024-07-31
19 Macrophage-fibroblast crosstalk drives Arg1-dependent lung fibrosis via ornithine loading
Yadav, P.; Gomez Ortega, J.; Tamaki, W.; Chien, C.; Chang, K.-C.; Biswas, N.; Pan, S.; Nilsson, J.; Yin, X.; Bhattacharyya, A.; Boostanpour, K.; Jujaray, T.; Wang, J.; Tsukui, T.; Sheppard, D.; Li, B.; Maishan, M.; Taenaka, H.; Matthay, M.; Muramatsu, R.; Maliskova, L.; Ghosh, A.; Eckalbar, W.; Molofsky, A. B.; Wolters, P. J.; Tamaki, S.; Bivona, T.; Abate, A. R.; Wagner, A.; Tharp, K.; Bhattacharya, M.
10.1101/2023.09.06.556606 — immunology — Posted on 2024-07-31
20 Neurexin 3 is Essential for the Specific Wiring of a Color Pathway in the Mammalian Retina
Kunze, V. P.; Angueyra, J. M.; Ball, J. M.; Thomsen, M. B.; Li, X.; Sabnis, A.; Nadal-Nicolas, F. M.; Li, W.
10.1101/2023.02.13.527055 — neuroscience — Posted on 2024-07-31
21 Prolactin-mediates a lactation-induced suppression of arcuate kisspeptin neuronal activity necessary for lactational infertility in mice
Hackwell, E. C. R.; Ladyman, S. R.; Clarkson, J.; McQullian, H. J.; Boehm, U.; Herbison, A. E.; Brown, R. S. E.; Grattan, D. R.
10.1101/2024.01.26.577359 — neuroscience — Posted on 2024-07-31
24 B-BIND: Biophysical Bayesian Inference forNeurodegenerative Dynamics
Agrawal, A.; Rachleff, V. M.; Travaglini, K. J.; Mukherjee, S.; Crane, P. K.; Hawrylycz, M.; Keene, C. D.; Lein, E.; Mena, G. E.; Gabitto, M. I.
10.1101/2024.06.10.597236 — neuroscience — Posted on 2024-07-31
25 Establishing And Maintaining The Blood-Brain Barrier: Epigenetic And Signaling Determinants.
Pandit, P. K. T.; Sadanandan, J.; Thomas, S.; Mathew, I. E.; Huang, Z.; Blackburn, S. L.; Tandon, N.; Lokhande, H.; McCrea, P. D.; Bresnick, E. H.; Dash, P. K.; McBride, D. W.; Harmanci, A.; Ahirwar, L. K.; Jose, D.; Dienel, A. C.; Zeineddine, H. A.; Hong, S.
10.1101/2022.11.29.516809 — neuroscience — Posted on 2024-07-31
29 Natural Selection in a Synthetic Yeast Endosymbiont Promotes Stable Coexistence
Supekova, L.; Zhou, H.; Barcellos, I. H.; Nguyen, C.; Dik, D. A.; Schultz, P. G.
10.1101/2024.07.31.606091 — synthetic biology — Posted on 2024-07-31
32 Identifying interactions between TDP-43 N-terminal and RNA binding domains
Scott, D. D.; Jena, L.; Perez-Miller, S.; Kumirov, V.; Khanna, R.; Khanna, M.
10.1101/2024.07.31.604183 — biophysics — Posted on 2024-07-31
36 Lymphatic endothelial cell-targeting lipid nanoparticles delivering VEGFC mRNA improve lymphatic function after injury
Michalaki, E.; Chin, R.; Jeong, K.; Qi, Z.; Liebman, L. N.; Gonzalez-Vargas, Y.; Echeverri, E. S.; Paunovska, K.; Muramatsu, H.; Pardi, N.; Tamburini, B. J.; Jakus, Z.; Dahlman, J. E.; Dixon, J. B.
10.1101/2024.07.31.605343 — bioengineering — Posted on 2024-07-31
37 Beta-arrestin 1 mediated Src activation via Src SH3 domain revealed by cryo-electron microscopy
Pakharukova, N.; Thomas, B. N.; Bansia, H.; Li, L.; Abzalimov, R. R.; Kim, J.; Kahsai, A. W.; Pani, B.; Bassford, D. K.; Liu, S.; Zhang, X.; des Georges, A.; Lefkowitz, R. J.
10.1101/2024.07.31.605623 — biochemistry — Posted on 2024-07-31
40 Cathelicidin antimicrobial peptides mediate immune protection of marsupial neonates
Park, J.; Ke, W.; Kaage, A.; Feigin, C. Y.; Pritykin, Y.; Donia, M. S.; Mallarino, R.
10.1101/2024.07.29.605640 — evolutionary biology — Posted on 2024-07-31
42 Integrating metabolic scaling and coexistence theories
Saavedra, S.; Arroyo, J. I.; Deng, J.; Marquet, P. A.; Kempes, C. P.
10.1101/2023.02.28.530509 — ecology — Posted on 2024-07-31
44 Decoding protein phosphorylation during oocyte meiotic divisions using phosphoproteomics
Peshkin, L.; Daldello, E. M.; Van Itallie, E. S.; Sonnett, M.; Kreuzer, J.; Haas, W.; Kirschner, M. W.; Jessus, C.
10.1101/2024.07.26.605364 — developmental biology — Posted on 2024-07-31
45 Depletion of endomembrane reservoirs drives phagocytic appetite exhaustion in macrophages
Fountain, A.; Mansat, M.; Soffiaturo, S.; Gimenez, M. C.; Moussaoui, S.; Ezzo, M.; Verdawala, M. B.; Fung, K.; Lancaster, C.; Somerville, E.; Hinz, B.; Terebiznik, M.; Botelho, R. J.
10.1101/2024.07.31.605905 — cell biology — Posted on 2024-07-31
47 mDia2 is an important mediator of MRTF-A-dependent regulation of breast cancer cell migration
Eder, I.; Yu, V.; Antonello, J.; Chen, F.; Gau, D.; Chawla, P.; Joy, M.; Lucas, P.; Boone, D.; LEE, A. V.; Roy, P.
10.1101/2023.12.21.572883 — cell biology — Posted on 2024-07-31
48 4D structural biology: quantitative dynamics in the eukaryotic RNA exosome complex
Liebau, J.; Lazzaretti, D.; Fuertges, T.; Bichler, A.; Pilsl, M.; Rudack, T.; Sprangers, R.
10.1101/2024.01.28.577622 — molecular biology — Posted on 2024-07-31
49 Non-genetic messenger RNA silencing reveals essential genes in phage-host interplay
Gerovac, M.; Thurica-Mitic, S.; Buhlmann, L.; Rech, V.; Zhu, Y.; Carien, S.; Popella, L.; Vogel, J.
10.1101/2024.07.31.605949 — molecular biology — Posted on 2024-07-31
50 Transcriptional regulation of adipocyte lipolysis by IRF2BP2
Chen, Y.; Liu, L.; Calhoun, R.; Cheng, L.; Merrick, D.; Steger, D.; Seale, P.
10.1101/2024.07.31.605689 — molecular biology — Posted on 2024-07-31
51 Identification of novel fructo-oligosaccharide bacterial consumers by pulse metatranscriptomics in a human stool sample
Prattico, C.; Gonzalez, E.; Dridi, L.; Jazestani, S.; Low, K.; Abbott, W.; Maurice, C. F.; Castagner, B.
10.1101/2024.07.31.606081 — microbiology — Posted on 2024-07-31
52 Comprehensive Assessment of Initial Adaptation of ESBL Positive ST131 Escherichia coli to Carbapenem Exposure
Shropshire, W. C.; Song, X.; Bremer, J.; Seo, S.; Rodriguez, S.; Anand, S. S.; Dinh, A. Q.; Bhatti, M. M.; Konovalova, A.; Arias, C. A.; Kalia, A.; Shamoo, Y.; Shelburne, S. A.
10.1101/2024.07.31.606066 — microbiology — Posted on 2024-07-31
53 Assessing the effects of warming and carbonate chemistry parameters on marine microbes in the Gulf of Mexico through basin-scale DNA metabarcoding
Anderson, S. R.; Silliman, K.; Barbero, L.; Gomez, F. A.; Stauffer, B. A.; Schnetzer, A.; Kelble, C. R.; Thompson, L. R.
10.1101/2024.07.30.605667 — microbiology — Posted on 2024-07-31
54 Dietary fiber content in clinical ketogenic diets modifies the gut microbiome and seizure resistance in mice
Ozcan, E.; Yu, K. B.; Dinh, L.; Lum, G.; Lau, K.; Hsu, J.; Arino, M.; Paramo, J.; Lopez-Romero, A.; Hsiao, E. Y.
10.1101/2024.07.31.606041 — microbiology — Posted on 2024-07-31
55 An IL-12 mRNA-LNP adjuvant enhances mRNA vaccine induced CD8+ T cell responses
Aunins, E. A.; Phan, A. T.; Alameh, M.-G.; Cruz-Morales, E.; Christian, D. A.; Bunkofske, M. E.; Dwivedi, G.; Kedl, R.; Weissman, D.; Hunter, C. A.
10.1101/2024.07.29.605626 — immunology — Posted on 2024-07-31
58 Comparative Analysis of Antioxidant Activity, ROS, and Relative Water Content Between Red and Green Cabbage
Sojib, M. R.; Methela, N. J.; Das, B.; Siddique, M. N. A.; Sultana, S.; Karim, A.; Islam, R.; Jone, M. J. H.
10.1101/2024.07.27.605406 — plant biology — Posted on 2024-07-31
62 Active Learning-Assisted Directed Evolution
Yang, J.; Lal, R. G.; Bowden, J. C.; Astudillo, R.; Hameedi, M. A.; Kaur, S.; Hill, M.; Yue, Y.; Arnold, F. H.
10.1101/2024.07.27.605457 — bioengineering — Posted on 2024-07-31
65 Activation of the mitochondrial unfolded protein response regulates the formation of stress granules
Lopez-Nieto Jordana, M.; Sun, Z.; Relton, E.; Safakli, R.; Freibaum, B. D.; Taylor, J. P.; Ruggieri, A.; Smyrnias, I.; Locker, N.
10.1101/2023.10.26.564187 — cell biology — Posted on 2024-07-31
66 p110alpha-dependent hepatocyte signaling is critical for liver gene expression and its rewiring in MASLD
Regnier, M.; Polizzi, A.; Fougeray, T.; Fougerat, A.; Perrier, P.; Anderson, K.; Lippi, Y.; Smati, S.; Lukowicz, C.; Lasserre, F.; Fouche, E.; Huillet, M.; Rives, C.; Tramunt, B.; Naylies, C.; Garcia, G.; Rousseau-Bacquie, E.; Bertrand-Michel, J.; Canlet, C.; Chevolleau-Mege, S.; Debrauwer, L.; Heymes, C.; Burcelin, R.; Levade, T.; Gourdy, P.; Wahli, W.; Blum, Y.; Gamet-Payrastre, L.; Ellero-Simatos, S.; Guillermet-Guibert, J.; Hawkins, P.; Stephens, L.; Montagner, A.; Loiseau, N.; Guillou, H.
10.1101/2024.01.09.574858 — cell biology — Posted on 2024-07-31
67 Effects of two different compounds on seizure suppression using the zebrafish PTZ-seizure model
Fernandez, J. A. A.; de Moura, T. C.; Vila, S. F.; Gaytan, J. A. R.; Lopez-Diaz, I.; Learte-Aymami, S.; Vazquez, M. E.; Mayan, M. D.; Sanchez, L.; Maurer-Morelli, C. V.
10.1101/2024.07.29.605666 — neuroscience — Posted on 2024-07-31
70 TET proteins regulate Drosha expression and impact microRNAs in iNKT cells
Gioulbasani, M.; Aijo, T.; Valenzuela, J. E.; Buquera Bettes, J.; Tsagaratou, A.
10.1101/2024.07.31.605991 — immunology — Posted on 2024-07-31
71 Complete sequencing of ape genomes
Yoo, D.; Rhie, A.; Hebbar, P.; Antonacci, F.; Logsdon, G. A.; Solar, S. J.; Antipov, D.; Pickett, B. D.; Safonova, Y.; Montinaro, F.; Luo, Y.; Malukiewicz, J.; Storer, J. M.; Lin, J.; Sequeira, A. N.; Mangan, R. J.; Hickey, G.; Anez, G. M.; Balachandran, P.; Bankevich, A.; Beck, C. R.; Biddanda, A.; Borchers, M.; Bouffard, G. G.; Brannan, E.; Brooks, S. Y.; Carbone, L.; Carrel, L.; Chan, A. P.; Crawford, J.; Diekhans, M.; Engelbrecht, E.; Feschotte, C.; Formenti, G.; Garcia, G. H.; Gennaro, L. d.; Gilbert, D.; Green, R. E.; Guarracino, A.; Gupta, I.; Haddad, D.; Han, J.; Harris, R. S.; Hartley
10.1101/2024.07.31.605654 — genomics — Posted on 2024-07-31
72 PRMT7 mediated PTEN activation promotes bone formation in female mice
Zhang, Y.; Qing, J.; Li, Y.; Gao, X.; Lu, D.; Wang, Y.; Gu, L.; Zhang, H.; Li, Z.; Wang, X.; Zhou, Y.; Zhang, P.
10.1101/2024.07.31.605998 — developmental biology — Posted on 2024-07-31
74 Encephalomyocarditis virus protein 2B* antagonises innate immune signalling by interacting with 14-3-3 protein family members
Nguyen, S. K.; Holmes, S.; Barrow, H. G.; Lukhovitskaya, N.; Jahun, A. S.; Georgana, I.; Caller, L. G.; Edgar, J. R.; Emmott, E.; Firth, A.; Stewart, H.
10.1101/2024.07.31.605952 — microbiology — Posted on 2024-07-31
75 Comparative analysis of the treatment-naive microbiome across rheumatic diseases to predict MTX treatment response
Amend, L.; Huang, K. D.; Sivapornnukul, P.; Rabenow, M.; Bielecka, A.; Wang, X.-Y.; Neumann-Schaal, M.; Witte, T.; Strowig, T.
10.1101/2024.07.31.605913 — microbiology — Posted on 2024-07-31
76 Citizen science informs demand-driven breeding of opportunity crops
Voss, R.; de Sousa, K.; N'Danikou, S.; Shango, A. J.; Aglinglo, L. A.; Laporte, M.-A.; Legba, E. C.; Houdegbe, A. C.; Diarra, D. d. Y.; Dolo, A.; Sidibe, A.; Ouedraogo, C. O.; Coulibaly, H.; Achigan-Dako, E. G.; Kileo, A.; Malulu, D.; Matumbo, Z.; Dinssa, F. F.; van Heerwaarden, J.; van Etten, J.; Riar, A.; van Zonneveld, M.
10.1101/2024.07.31.605211 — plant biology — Posted on 2024-07-31
77 Low-dose colchicine treatment improves vasorelaxation, reduces arterial remodeling and attenuates blood pressure increases in spontaneously hypertensive rats
Baldwin, S. N.; Bastrup, J. A.; van der Horst, J.; Formento, A. M. G.; Dubik, M.; Kudryavtseva, O. S.; Saljic, A.; Rognant, S.; Dannesboe, J.; Mozzicato, A. M.; Jespersen, T.; Moeller, J. B.; Tardif, J.-C.; Thomsen, M. B.; Jepps, T. A.
10.1101/2024.07.31.604256 — physiology — Posted on 2024-07-31
79 Dynorphin modulates motivation through a pallido-amygdala cholinergic circuit
Li, B.; Sun, Q.; Liu, M.; Guan, W.; Xiao, X.; Dong, C.; Bruchas, M.; Zweifel, L.; Li, Y.; Tian, L.
10.1101/2024.07.31.605785 — neuroscience — Posted on 2024-07-31
80 Modelling Protein-Glycan Interactions with HADDOCK
Ranaudo, A.; Giulini, M.; Pelissou Ayuso, A.; Bonvin, A. M.
10.1101/2024.07.31.605986 — bioinformatics — Posted on 2024-07-31
82 Quantitative Label-Free Single-Cell Proteomics on the Orbitrap Astral MS
Petrosius, V.; Aragon-Fernandez, P.; Arrey, T. N.; Woessmann, J.; Üresin, N.; de Boer, B.; Su, J.; Furtwängler, B.; Stewart, H.; Denisov, E.; Petzoldt, J.; Peterson, A. C.; Hock, C.; Damoc, E.; Makarov, A. A.; Zabrouskov, V.; Porse, B. T.; Schoof, E. M.
10.1101/2024.07.31.605978 — biochemistry — Posted on 2024-07-31
85 Resource Quality Differentially Impacts Daphnia Interactions with Two Parasites
Fearon, M. L.; Sanchez, K. F.; Sun, S.-J.; Calhoun, S. K.; Monell, K. J.; Ravichandran, V.; Duffy, M. A.
10.1101/2024.07.31.605800 — ecology — Posted on 2024-07-31
86 HMCES corrupts replication fork stability during base excision repair in homologous recombination deficient cells
Pena-Gomez, M. J.; Rodriguez Martin, Y.; del Rio Oliva, M.; Masson, J.-Y.; Reyes, J. C.; Rosado, I. V.
10.1101/2024.07.31.605977 — molecular biology — Posted on 2024-07-31
89 Contributions of genetic variation in astrocytes to cell and molecular mechanisms of risk and resilience to late onset Alzheimer's disease
Lee, H.; Pearse, R. V.; Lish, A. M.; Pan, C.; Augur, Z. M.; Terzioglu, G.; Gaur, P.; Liao, M.; Fujita, M.; Tio, E. S.; Duong, D. M.; Felsky, D.; Seyfried, N. T.; Menon, V.; Bennett, D. A.; De Jager, P. L.; Young-Pearse, T. L.
10.1101/2024.07.31.605928 — neuroscience — Posted on 2024-07-31
91 Human PrP E219K as a new and promising substrate for RT-QuIC amplification of human prion strains: a first step towards strain discrimination
Marin-Moreno, A.; Reine, F.; Jaffrezic, F.; Herzog, L.; Rezaei, H.; Quadrio, I.; Haik, S.; Beringue, v.; Martin, D.
10.1101/2024.07.31.605973 — pathology — Posted on 2024-07-31
96 Temperature drives seagrass recovery across the Western North Atlantic
Smulders, F.; Campbell, J.; Altieri, A.; Armitage, A.; Bakker, E.; Barry, S.; Becker, T.; Bethel, E.; Douglass, J.; van Duijnhoven, H.; de Fouw, J.; Frazer, T.; Glazner, R.; Goeke, J.; Gort, G.; Heck, K.; Kramer, O.; van de Leemput, I.; Manuel, S.; Martin, C.; Martinez Lopez, I.; McDonald, A.; Munson, C.; O'Shea, O.; Paul, V.; Reynolds, L.; Rhoades, K.; Rodriguez Bravo, L.; Sang, A.; Sawall, Y.; Smith, K.; Thompson, J.; van Tussenbroek, B.; Wied, W.; Christianen, M.
10.1101/2024.07.31.605761 — ecology — Posted on 2024-07-31
100 Nonlinear sound-sheet microscopy: imaging opaque organs at the capillary and cellular scale
Heiles, B.; Nelissen, F.; Terwiel, D.; Park, B. M.; Munoz Ibarra, E.; Matalliotakis, A.; Waasdorp, R.; Ara, T.; Barturen-Larrea, P.; Duan, M.; Shapiro, M. G.; Gazzola, V.; Maresca, D.
10.1101/2024.07.31.605825 — bioengineering — Posted on 2024-07-31
101 Introducing identification probability for automated and transferable assessment of metabolite identification confidence in metabolomics and related studies
Metz, T. O.; Chang, C. H.; Gautam, V.; Anjum, A.; Tian, S.; Wang, F.; Colby, S. M.; Nunez, J. R.; Blumer, M. R.; Edison, A. S.; Fiehn, O.; Jones, D. P.; Li, S.; Morgan, E. T.; Patti, G. J.; Ross, D. H.; Shapiro, M. R.; Williams, A. J.; Wishart, D. S.
10.1101/2024.07.30.605945 — biochemistry — Posted on 2024-07-31
104 An LNP-mRNA vaccine provides potent immunogenicity and protection against Mycobacterium tuberculosis
Lukeman, H.; Al-Wassiti, H.; Fabb, S. A.; Lim, L.; Wang, T.; Britton, W. J.; Steain, M.; Pouton, C. W.; Triccas, J.; Counoupas, C.
10.1101/2024.07.31.605765 — immunology — Posted on 2024-07-31
106 Cholecystokinin modulates age-dependent Thalamocortical Neuroplasticity
Li, X.; Feng, J.; Hu, X.; Zhou, P.; Chen, T.; Zheng, X.; Jendrichovsky, P.; Wang, X.; Chen, M.; Li, H.; Chen, X.; Zeng, D.; Zhang, M.; Xiao, Z.; He, L.; Bello, S. T.; He, J.
10.1101/2024.07.31.605964 — neuroscience — Posted on 2024-07-31
109 How different immersive environments affect intracortical brain computer interfaces
Tortolani, A. F.; Kunigk, N. G.; Sobinov, A. R.; Boninger, M. L.; Bensmaia, S. J.; Collinger, J. L.; Hatsopoulos, N. G.; Downey, J. E.
10.1101/2024.07.30.605911 — neuroscience — Posted on 2024-07-31
113 Tumour-derived extracellular vesicles within the therapy-induced senescent secretome distinctly suppress breast cancer via DKK1-mediated inflammatory response.
Robert, M.; Jakhar, R.; Au, B. V.; Eng, G. W. L.; Wei, M.; Gao, A. K.; Chuah, Y. H.; Sachaphibulkij, K.; Bonne, I.; Lim, K. J.; Sinha, I.; Teh, D. B. L.; Lim, L. H. K.; Kumar, P.; Verma, N. K.; Sze, N. S. K.; Lim, E. H.; Ong, D. S. T.; Cheong, J. K.; Itahana, K.; Conolly, J. E.; Crasta, K. C.
10.1101/2024.03.29.586905 — cancer biology — Posted on 2024-07-31
114 Reinforced polymer-nanoparticle hydrogels for subcutaneous and sustained delivery of trastuzumab
Bovone, G.; Bernhard, S.; Jacquot, G.; Mittelheisser, V.; Mirjolet, C.; Guzzi, E. A.; Garau Paganella, L.; Liebi, L.; Lefebvre, O.; Goetz, J.; Charbonniere, L.; Harlepp, S.; Pivot, X.; Tibbitt, M. W.; Detappe, A.
10.1101/2024.07.30.605810 — bioengineering — Posted on 2024-07-31
117 Development of an Organ-on-a-Chip for Correlative Microscopy: Visualizing Early Osteogenesis in 3D with High Resolution
Schaart, J. M.; Wasserberg, D.; Eufrasio Cruz, M. A.; Kea-te Lindert, M.; Van der Meijden, R. H. M.; Roverts, R.; Debera, N. D.; Lu, M. P.; Rouwkema, J.; Nijhuis, W. H.; van der Meer, A. D.; Jonkheijm, P.; Sommerdijk, N.; Akiva, A.
10.1101/2024.07.31.605958 — bioengineering — Posted on 2024-07-31
120 The Neuropeptide Sulfakinin, a peripheral regulator of insect behavior switch between mating and foraging
Li, H.-F.; Dong, B.; Peng, Y.-Y.; Luo, H.-Y.; Ou, X.-L.; Ren, Z.-L.; Park, Y.; Wang, J.-J.; Jiang, H.
10.1101/2024.07.30.605941 — ecology — Posted on 2024-07-31
121 An outline on the chemical phenotype flexibility of forest species: an eco-metabolomics study of Pinus uncinata along an altitudinal gradient
Rivas Ubach, A.; Aranda, I.; Sardans, J.; Liu, Y.; Diaz de Quijano, M.; Pasa-Tolic, L.; Oravec, M.; Urban, O.; Penuelas, J.
10.1101/2024.07.31.605974 — ecology — Posted on 2024-07-31
122 Ciliary biology intersects autism and congenital heart disease
Teerikorpi, N.; Lasser, M. C.; Wang, S.; Kostyanovskaya, E.; Bader, E.; Sun, N.; Dea, J.; Nowakowski, T. J.; Willsey, A. J.; Willsey, H.
10.1101/2024.07.30.602578 — developmental biology — Posted on 2024-07-31
124 Mechanism of neurodegeneration mediated by clonal inflammatory microglia
Vicario, R.; Fragkogianni, S.; Pokrovskii, M.; Mayer, C.; Lopez-Rodrigo, E.; Hu, Y.; Ogishi, M.; Alberdi, A.; Baako, A.; Ay, O.; Plu, I.; Sazdovitch, V.; Heritier, S.; Cohen-Aubart, F.; Shor, N.; Miyara, M.; Nguyen-Khac, F.; Viale, A.; Idbaih, A.; Amoura, Z.; Rosenblum, M.; Zhang, H.; Karnoub, E.-R.; Sashittal, P.; Jakatdar, A.; Iacobuzio-Donahue, C. A.; Abdel-Wahab, O.; Tabar, V.; Socci, N. D.; Elemento, O.; Diamond, E.; Boisson, B.; Casanova, J.-L.; Seilhean, D.; Haroche, J.; Donadieu, J.; Geissmann, F.
10.1101/2024.07.30.605867 — immunology — Posted on 2024-07-31
125 A novel and potent MICA/B antibody is therapeutically effective in KRAS LKB1 mutant lung cancer models
Kowash, R. R.; Sabnani, M.; Gray, L. T.; Deng, Q.; Girard, L.; Naito, Y.; Masahiro, K.; Minna, J. D.; Gerber, D. E.; Koyama, S.; Liu, Z. L.; Baruah, H.; Akbay, E. A.
10.1101/2024.07.30.605880 — immunology — Posted on 2024-07-31
128 It's the Sound not the Pulse: Peripheral Magnetic Stimulation Reduces Central Sensitization through Auditory Modulatory Effects
Abssy, S.; Osborne, N. R.; Osokin, E. E.; Tomin, R.; Honigman, L.; Khan, J. S.; De Vera, N.; Furman, A. J.; Mazaheri, A.; Seminowicz, D. A.; Moayedi, M.
10.1101/2024.07.30.605813 — neuroscience — Posted on 2024-07-31
130 Opioid-Induced Inter-regional Dysconnectivity Correlates with Analgesia in Awake Mouse Brains
Mariani, J.-C.; Diebolt, S.; Beynac, L.; Santos, R.; Schulz, S.; Deffieux, T.; Tanter, M.; LENKEI, Z.; Kliewer, A.
10.1101/2024.07.30.604249 — neuroscience — Posted on 2024-07-31
131 Spreading depolarizations exhaust neuronal ATP in a model of cerebral ischemia
Schoknecht, K.; Baeza-Lehnert, F.; Hirrlinger, J.; Dreier, J. P.; Eilers, J.
10.1101/2024.07.30.605834 — neuroscience — Posted on 2024-07-31
132 CIB2 function is distinct from Whirlin in the development of cochlear stereocilia staircase pattern
Giese, A. P. J.; Parker, A.; Rehman, S.; Brown, S. D. M.; Riazuddin, S.; Vander Kooi, C. W.; Bowl, M. R.; Ahmed, Z. M.
10.1101/2024.07.30.605852 — neuroscience — Posted on 2024-07-31
136 Sleep homeostasis in lizards and the role of cortex
Hatori, S.; Yamaguchi, S. T.; Kobayashi, R.; Matsui, F.; Zhou, Z.; Norimoto, H.
10.1101/2024.07.31.605950 — neuroscience — Posted on 2024-07-31
138 Phosphorylation of Zearalenone retains its toxicity
Asaduzzaman, M.; Pavlov, I. A.; St-Jean, G.; Zhu, Y.; Castex, M.; Chorfi, Y.; del Castillo, J. R. E.; Zhou, T.; Alassane-Kpembi, I.
10.1101/2024.07.30.605906 — pharmacology and toxicology — Posted on 2024-07-31
139 Insights into Therapeutic Discovery Through the Kelch Domain Structure of Keap1 at Ambient Temperature
YILMAZ, M.; SEVER, B.; KUTLU, Y.; GUL, M.; OKUDUCU, C.; TAVLI, S.; OTSUKA, M.; FUJITA, M.; HALILOGLU, T.; CIFTCI, H.; Demirci, H.
10.1101/2024.07.30.605796 — biophysics — Posted on 2024-07-31
140 Scaling and Merging Time-Resolved Laue Data with Variational Inference
Zielinski, K. A.; Dolamore, C.; Wang, H. K.; Henning, R. W.; Wilson, M. A.; Pollack, L.; Srajer, V.; Hekstra, D. R.; Dalton, K. M.
10.1101/2024.07.30.605871 — biophysics — Posted on 2024-07-31
142 Receptor Binding Specificity of a Bovine A(H5N1) Influenza Virus
Chopra, P.; Page, C. K.; Shepard, J. D.; Ray, S. D.; Kandeil, A.; Jeevan, T.; Bowman, A. S.; Ellebedy, A. H.; Webby, R. J.; de Vries, R. P.; Tompkins, S. M.; Boons, G.-J.
10.1101/2024.07.30.605893 — biochemistry — Posted on 2024-07-31
143 Video Foundation Models for Animal Behavior Analysis
Sun, J. J.; Zhou, H.; Zhao, L.; Yuan, L.; Seybold, B.; Hendon, D.; Schroff, F.; Ross, D. A.; Adam, H.; Hu, B.; Liu, T.
10.1101/2024.07.30.605655 — animal behavior and cognition — Posted on 2024-07-31
145 Expanding the space of self-reproducing RNAs using probabilistic generative models
Lambert, C. N.; Opuu, V.; Calvanese, F.; Zamponi, F.; Hayden, E. J.; Weigt, M. J.; Smerlak, M.; Nghe, P.
10.1101/2024.07.31.605758 — biochemistry — Posted on 2024-07-31
146 Thrombospondin-1 inhibits alternative complement pathway activation in vasculitis synergistically to factor H
Konwar, S.; Schroda, S.; Kleindienst, J.; Decker, E. L.; Pohl, M.; Zieger, B.; Panse, J.; Wang, H.; Grosse, R.; Rogg, M.; Schell, C. L.; Vidal, S.; Liu, X.; Gorzelanny, C.; Tschongov, T.; Haeffner, K.
10.1101/2024.07.31.606000 — molecular biology — Posted on 2024-07-31
147 Ganoderma lucidum alleviates kidney aging by modulating gut microbiota
Liu, X.; Zhao, J.; Liu, J.; Huang, Y.; Deng, W.; Yan, L.; Liu, X.; Cui, M.; Xiao, H.
10.1101/2024.07.30.605752 — microbiology — Posted on 2024-07-31
148 Loss of RREB1 reduces adipogenesis and improves insulin sensitivity in mouse and human adipocytes
Yu, G. Z.; Krentz, N. A. J.; Bentley, L.; Zhao, M.; Paphiti, K.; Sun, H.; Honecker, J.; Nygard, M.; Dashti, H.; Bai, Y.; Reid, M.; Thaman, S.; Wabitsch, M.; Rajesh, V.; Yang, J.; Mattis, K. K.; Abaitua, F.; Casero, R.; Hauner, H.; Knowles, J. W.; Wu, J. Y.; Mandrup, S.; Claussnitzer, M.; Svensson, K. J.; Cox, R. D.; Gloyn, A. L.
10.1101/2024.07.30.605923 — physiology — Posted on 2024-07-31
149 Central activation of catecholamine-independent lipolysis drives the end-stage catabolism of all adipose tissues
Zhang, X.; Majumdar, A.; Kim, C.; Kleiboeker, B.; Magee, K. L.; Learman, B. S.; Thomas, S. A.; Lodhi, I. J.; MacDougald, O. A.; Scheller, E. L.
10.1101/2024.07.30.605812 — physiology — Posted on 2024-07-31
150 Ketomimetic Nutrients Trigger a Dual Metabolic Defense in Breast Cancer Cells
Kamra, M.; Chen, Y.-I.; Delgado, P.; Seeley, E.; Seidlits, S.; YEH, H.-C.; Brock, A.; Parekh, S. H.
10.1101/2024.07.03.601966 — cancer biology — Posted on 2024-07-31
151 A yeast two-hybrid system to obtain triple-helical ligands from combinatorial random peptide libraries
Masuda, R.; Thant, K. P. P.; Kawahara, K.; Oki, H.; Kadonosono, T.; Kobayashi, Y.; Koide, T.
10.1101/2023.11.14.567114 — biochemistry — Posted on 2024-07-31
152 Carbohydrate-active enzymes from Akkermansia muciniphila breakdown mucin O-glycans to completion
Crouch, L. I.; Bakshani, C. R.; Ojuri, T. O.; Pilgaard, B.; Holck, J.; McInnes, R.; Zakhour, M.; Kerouedan, M.; Newton, E.; Bolam, D. N.; Kozak, R. P.; Cakaj, S.
10.1101/2024.03.27.586211 — biochemistry — Posted on 2024-07-31
154 Iron transport pathways in the human malaria parasite Plasmodium falciparum revealed by RNA-sequencing
Wunderlich, J.; Kotov, V.; Votborg-Novel, L.; Ntalla, C.; Geffken, M.; Peine, S.; Portugal, S.; Strauss, J.
10.1101/2024.04.18.590068 — cell biology — Posted on 2024-07-31
157 Regulatory T-cells in multiple sclerosis are activated by Epstein-Barr Virus and produce IL-10 in the central nervous system
Pulvirenti, N.; Righetti, C.; Clemente, F.; Serafini, B.; Pietroboni, A.; Galeota, E.; Rosicarelli, B.; Cordiglieri, C.; Iannone, C.; de Riz, M.; Vasco, C.; Espadas de Arias, A.; De Feo, T.; Valenti, L.; Prati, D.; Abrignani, S.; Gerosa, M.; Caporali, R.; Galimberti, D.; Scarpini, E.; Geginat, J.
10.1101/2024.07.30.605745 — immunology — Posted on 2024-07-31
161 Immune Digital Twin Blueprint: A Comprehensive Mechanistic Model of the Human Immune System
Amin, R.; Aghamiri, S.; Puniya, B. L.; Mayo, L.; Startsev, D.; Poore, K.; Helikar, R. M.; Helikar, T.
10.1101/2020.03.11.988238 — systems biology — Posted on 2024-07-31
162 Defense-related callose synthase PMR4 promotes root hair callose deposition and adaptation to phosphate deficiency in Arabidopsis thaliana
Okada, K.; Yachi, K.; Nguyen, T. A. N.; Kanno, S.; Yasuda, S.; Tadai, H.; Tateda, C.; Lee, T.-H.; Nguyen, U.; Inoue, K.; Tsuchida, N.; Ishihara, T.; Miyashima, S.; Hiruma, K.; Miwa, K.; Maekawa, T.; Notaguchi, M.; Saijo, Y.
10.1101/2023.07.05.547890 — plant biology — Posted on 2024-07-31
164 EmbedGEM: A framework to evaluate the utility of embeddings for genetic discovery
Mukherjee, S.; McCaw, Z. R.; Pei, J.; Merkoulovitch, A.; Tandon, R.; Soare, T. W.; Amar, D.; Somineni, H.; Klein, C.; Satapati, S.; Lloyd, D.; Probert, C.; Insitro Research Team, ; Koller, D.; O'Dushlaine, C.; Karaletsos, T.
10.1101/2023.11.24.568344 — bioinformatics — Posted on 2024-07-31
168 Myeloid-Specific Thrombospondin-1 Deficiency Exacerbates Aortic Rupture via Broad Suppression of Extracellular Matrix Proteins
Zhou, T.; Yang, H.; Assa, C.; DeRoo, E.; Bontekoe, J.; Burkel, B.; Ponik, S. M.; Lu, H. S.; Daugherty, A.; Liu, B.
10.1101/2024.07.30.605216 — pathology — Posted on 2024-07-31
171 A survey of ADP-ribosyltransferase families in the pathogenic Legionella
Krysinska, M.; Gradowski, M.; Baranowski, B.; Pawlowski, K.; Dudkiewicz, M.
10.1101/2024.07.30.605764 — bioinformatics — Posted on 2024-07-31
173 Logan: Planetary-Scale Genome Assembly Surveys Life's Diversity
Chikhi, R.; Raffestin, B.; Korobeynikov, A.; Edgar, R. C.; Babaian, A.
10.1101/2024.07.30.605881 — bioinformatics — Posted on 2024-07-31
176 Annotation Vocabulary (Might Be) All You Need
Hallee, L.; Rafailidis, N.; Horger, C.; Hong, D.; Gleghorn, J. P.
10.1101/2024.07.30.605924 — bioinformatics — Posted on 2024-07-31
177 A rapid CAT transformation protocol and nuclear transgene expression tools for metabolic engineering in Cyanidioschyzon merolae 10D
Villegas-Valencia, M.; Stark, M. R.; Seger, M.; Wellman, G. B.; Overmans, S.; Lammers, P. J.; Rader, S. D.; Lauersen, K. J.
10.1101/2024.07.30.605877 — bioengineering — Posted on 2024-07-31
181 Mechanistic origin and preimplantation development of uniparental and polyploid blastomeres
Zhao, Y.; Fernandez-Montoro, A.; Peeters, G.; Jatsenko, T.; De Coster, T.; Angel-Velez, D.; Lefevre, T.; Voet, T.; Tsuiko, O.; Kurg, A.; Smits, K.; Van Soom, A.; Vermeesch, J. R.
10.1101/2024.07.30.605883 — genetics — Posted on 2024-07-31
183 wQFM-TREE: highly accurate and scalable quartet-based species tree inference from gene trees
Rafi, A.; Rumi, A. M. S.; Hakim, S. A.; Sohaib, S.; Tahmid, M. T.; Momin, R. J. I.; Zaman, T. A.; Reaz, R.; Bayzid, M. S.
10.1101/2024.07.30.605630 — evolutionary biology — Posted on 2024-07-31
184 ERGA-BGE genome of Valencia hispanica (Valenciennes, 1826): a critically endangered Iberian toothcarp
Ventura, M.; Franch, N.; Fernandez, R.; Palma-Guerrero, J.; Böhne, A.; Monteiro, R.; Aguilera, L.; Gut, M.; Alioto, T. S.; Camara Ferreira, F.; Cruz, F.; Gomez-Garrido, J.; Haggerty, L.; Martin, F.; Brown, T.
10.1101/2024.07.31.604920 — evolutionary biology — Posted on 2024-07-31
187 An effective model for community-based conservation around authorized fishing settlements inside a devolved Wildlife Management Area in southern Tanzania
Duggan, L. M.; Tarimo, L. J.; Walsh, K. A.; Kavishe, D. R.; Crego, R. D.; Elisa, M.; Mombo, F.; Butler, F.; Killeen, G.
10.1101/2024.07.30.605829 — ecology — Posted on 2024-07-31
189 Bacteria combine polar- and dispersed-growth to power cell elongation and wall width dynamics
Zambri, M. P.; Baglio, C. R.; Irazoki, O.; Jones, S. E.; Garner, E. C.; Cava, F.; Elliot, M. A.
10.1101/2024.07.30.605496 — microbiology — Posted on 2024-07-31
193 Isolation and characterization of cell wall and extracellular polysaccharides from cultures of the mycoparasitic strain Tirochoderma koningiopsis
Nowak, A.; Wlizło, K.; Komaniecka, I.; Szymanska-Chargot, M.; Zdunek, A.; Kapral-Piotrowska, J.; Tyskiewicz, K.; Jaroszuk-Sciseł, J.
10.1101/2024.07.31.605896 — microbiology — Posted on 2024-07-31
196 Circulating mucosal-like IgA responses associate with severity of Puumala orthohantavirus-caused hemorrhagic fever with renal syndrome
Cabrera, L.; Buckner, C.; Martinez, V.; Maki, S.; Vapalahti, O.; Vaheri, A.; Hepojoki, J.; Tietavainen, J.; Makela, S.; Mustonen, J.; Strandin, T.
10.1101/2024.07.30.605778 — immunology — Posted on 2024-07-31
197 Transcriptomic analysis of the functions of CSF1R-dependent macrophages in postnatal development in the rat
Carter-Cusack, D.; Huang, S.; Keshvari, S.; Patkar, O.; Sehgal, A.; Allavena, R.; Byrne, R.; Morgan, P.; Bush, S. J.; Summers, K. M.; Irvine, K. M.; Hume, D. A.
10.1101/2024.07.30.605701 — immunology — Posted on 2024-07-31
198 Cortical Acetylcholine Response to Deep Brain Stimulation of the Basal Forebrain
Shanazz, K.; Xie, K.; Oliver, T.; Bogan, J.; Vale Diaz, F.; Sword, J.; Kirov, S. A.; Terry, A.; O'Herron, P.; Blake, D. T.
10.1101/2024.07.30.605828 — neuroscience — Posted on 2024-07-31
199 Senescent cell clearance ameliorates temporal lobe epilepsy and associated spatial memory deficits in mice
Khan, T.; McFall, D. J.; Hussain, A. I.; Frayser, L. A.; Casilli, T. P.; Steck, M. C.; Sanchez Brualla, I.; Kuehn, N. M.; Cho, M.; Barnes, J. A.; Harris, B. T.; Vicini, S.; Forcelli, P. A.
10.1101/2024.07.30.605784 — neuroscience — Posted on 2024-07-31
200 Enhancer AAVs for targeting spinal motor neurons and descending motor pathways in rodents and macaque
Kussick, E.; Johansen, N.; Taskin, N.; Wynalda, B.; Martinez, R.; Groce, E. L.; Reding, M.; Liang, E.; Shulga, L.; Huang, C.; Casper, T.; Clark, M.; Ho, W.; Gao, Y.; van Velthoven, C. T. J.; Sobieski, C.; Ferrer, R.; Berg, M. R.; Curtis, B. C.; English, C.; Day, J. C.; Fortuna, M.; Donadio, N.; Newman, D.; Yao, S.; Chakka, A. B.; Goldy, J.; Torkelson, A.; Guzman, J. B.; Chakrabarty, R.; Nguy, B.; Guilford, N.; Pham, T. H.; Wright, V.; Ronellenfitch, K.; Gudsnuk, K.; Thyagarajan, B.; Smith, K. A.; Dee, N.; Zeng, H.; Yao, Z.; Tasic, B.; Levi, B. P.; Hodge, R.; Bakken, T. E.; Lein, E. S.; Ting, J
10.1101/2024.07.30.605864 — neuroscience — Posted on 2024-07-31
201 A computational model of altered neuronal activity in altered gravity
Gontier, C.; Kalinski, L.; Striebel, J.; Sturm, M.; Meerholz, Z.; Schunk, S.; Lichterfeld, Y.; Liemersdorf, C.
10.1101/2024.07.30.605832 — neuroscience — Posted on 2024-07-31
202 The big tau splice isoform resists Alzheimer's-related pathological changes
Chung, D.-e. C.; Deng, X.; Yalamanchili, H. K.; Revelli, J.-P.; Han, A. L.; Tadros, B.; Richman, R.; Dias, M.; Alavi Naini, F.; Boeynaems, S.; Hyman, B. T.; Zoghbi, H. Y.
10.1101/2024.07.30.605685 — neuroscience — Posted on 2024-07-31
204 Transcriptome profiling of maize transcription factor mutants to probe gene regulatory network predictions
Ellison, E. L.; Zhou, P.; Chu, Y.-H.; Hermanson, P.; Gomez-Cano, L.; Myers, Z. A.; Abnave, A.; Gray, J.; Hirsch, C. N.; Grotewold, E.; Springer, N. M.
10.1101/2024.07.30.605884 — plant biology — Posted on 2024-07-31
207 Unraveling cysteine deficiency-associated rapid weight loss
Varghese, A.; Gusarov, I.; Gamallo-Lana, B.; Dolgonos, D.; Mankan, Y.; Shamovsky, I.; Phan, M.; Jones, R.; Gomez-Jenkins, M.; White, E.; Wang, R.; Jones, D.; Papagiannakopoulos, T.; Pacold, M. E.; Mar, A. C.; Littman, D. R.; Nudler, E.
10.1101/2024.07.30.605703 — physiology — Posted on 2024-07-31
213 MRI signatures of cortical microstructure in human development align with oligodendrocyte cell-type expression
Genc, S.; Ball, G.; Chamberland, M.; Raven, E. P.; Tax, C. M.; Ward, I.; Yang, J. Y.; Palombo, M.; Jones, D. K.
10.1101/2024.07.30.605934 — neuroscience — Posted on 2024-07-30
215 Hypersynchronous iPSC-derived SHANK2 neuronal networks are rescued by mGluR5 agonism
McCready, F. P.; Pradeepan, K. S.; Khaki, M.; Wei, W.; Matusiak, N.; Piekna, A.; Martinez-Trujillo, J. C.; Ellis, J.
10.1101/2024.07.30.605451 — neuroscience — Posted on 2024-07-30
218 ChemPrint: An AI-Driven Framework for Enhanced Drug Discovery
Umansky, T.; Woods, V.; Russell, S. M.; Smith, D. M.; Haders, D.
10.1101/2024.03.22.586314 — bioinformatics — Posted on 2024-07-30
219 Enzymatic synthesis of isotopically labeled hydrogen peroxide for mass spectrometry-based applications
Hoare, M.; Tan, R.; Militi, I.; Welle, K. A.; Swovick, K.; Hryhorenko, J. R.; Ghaemmaghami, S.
10.1101/2024.07.30.605865 — biochemistry — Posted on 2024-07-30
220 Multi-omics approaches define novel aphid effector candidates associated with virulence and avirulence phenotypes
Thorpe, P.; Altmann, S.; Lopez-Cobollo, R.; Douglas, N.; Iqbal, J.; Kanvil, S.; Simon, J.-C.; Carolan, J. C.; Bos, J.; Turnbull, C.
10.1101/2024.07.30.605808 — genomics — Posted on 2024-07-30
224 Enhanced RNAi does not provide efficient innate antiviral immunity in mice in vivo.
Kulmann, M. I. R.; Taborska, E.; Benkoova, B.; Palus, M.; Drobek, A.; Horvat, F.; Pasulka, J.; Malik, R.; Salyova, E.; Honig, V.; Pellerova, M.; Borsanyiova, M.; Stepanek, O.; Bopegamage, S.; Ruzek, D.; Svoboda, P.
10.1101/2024.07.29.605661 — molecular biology — Posted on 2024-07-30
225 Metabolic alterations drive inflammatory phenotypes in CHIP-associated heart failure
Mansouri, S.; Hemmerling, I.; Hesami, G.; Cremer, S.; Kirschbaum, K.; Klatt, S.; Behjati, F.; Schulz, M. H.; Li, X.; Scheller, M.; Mueller-Tidow, C.; Arndt, P.; Guenther, S.; Nandigama, M.-S.; Looso, M.; A. Rieger, M.; Kuhnert, S.; Vogelmeier, C. F.; Bals, R.; Fleming, I.; Zeiher, A.; Seeger, W.; Leuschner, F.; Savai, R.; Dimmeler, S.; Pullamsetti, S. S.
10.1101/2024.07.30.605744 — molecular biology — Posted on 2024-07-30
226 The integrated stress response regulates 18S nonfunctional rRNA decay in mammals
Coria, A. R.; Shah, A.; Shafieinour, M.; Taylor, S. J.; Guiblet, W.; Miller, J. T.; Mani Sharma, I.; Wu, C. C.-C.
10.1101/2024.07.30.605914 — molecular biology — Posted on 2024-07-30
228 Closing the genome of Teredinibacter turnerae T7902 by long-read nanopore sequencing
Gasser, M. T.; Liu, A.; Flatau, R.; Altamia, M. A.; Filone, C. M.; Distel, D. L.
10.1101/2024.07.30.605897 — microbiology — Posted on 2024-07-30
229 In situ deposition of nanobodies by an engineered commensal microbe promotes survival in a mouse model of enterohemorrhagic E. coli
Srivastava, R.; Gonzalez-Prieto, C.; Lynch, J.; Muscolo, M.; Lin, C.; Brown, M. A.; Lemos, L.; Shrestha, A.; Osburne, M.; Leong, J. M.; Lesser, C. F.
10.1101/2024.07.30.605899 — microbiology — Posted on 2024-07-30
232 Multiplicity of Type 6 Secretion System toxins limits the evolution of resistance
Smith, W. P. J.; Armstrong-Bond, E.; Coyte, K. Z.; Knight, C.; Basler, M.; Brockhurst, M.
10.1101/2024.07.30.605577 — microbiology — Posted on 2024-07-30
237 Dynamics of antimicrobial resistance and virulence of Salmonella enterica serovar Dublin
Sia, C. M.; Ambrose, R. L.; Valcanis, M.; Andersson, P.; Ballard, S. A.; Howden, B. P.; Williamson, D. A.; Pearson, J. S.; Ingle, D. J.
10.1101/2024.07.30.605691 — microbiology — Posted on 2024-07-30
238 Assessing the effects of warming and carbonate chemistry parameters on marine microbes in the Gulf of Mexico through basin-scale DNA metabarcoding
Anderson, S. R.; Silliman, K.; Barbero, L.; Gomez, F. A.; Stauffer, B. A.; Schnetzer, A.; Kelble, C. R.; Thompson, L. R.
10.1101/2024.07.30.605667 — microbiology — Posted on 2024-07-30
239 Understanding the Transfer and Persistence of Antimicrobial Resistance in Aquaculture Using a Model Teleost Gut System
Barcan, A. S.; Humble, J. L.; Kasaragod, S.; Sajib, M. S. I.; Barcan, R. A.; McGinnity, P.; Welch, T. J.; Robertson, B.; Vamanu, E.; Bagigalupo, A. E.; Llewellyn, M. S.; Samsing, F.
10.1101/2024.07.30.605792 — microbiology — Posted on 2024-07-30
240 Commensal-pathogen dynamics structure disease outcomes during Clostridioides difficile colonization
Fishbein, S.; DeVeaux, A. L.; Khanna, S.; Ferreiro, A. L.; Liao, J.; Agee, W.; Ning, J.; Mahmud, B.; Wallace, M. J.; Hink, T.; Reske, K. A.; Guruge, J.; Leekha, S.; Dubberke, E. R.; Dantas, G.
10.1101/2024.07.11.603094 — microbiology — Posted on 2024-07-30
241 Motor cortical dynamics are shaped by multiple distinct subspaces during naturalistic behavior
Perich, M. G.; Conti, S.; Badi, M.; Bogaard, A.; Barra, B.; Rajan, K.; Bloch, J.; Courtine, G.; Micera, S.; Capogrosso, M.; Milekovic, T.
10.1101/2020.07.30.228767 — neuroscience — Posted on 2024-07-30
242 Harnessing CRISPR interference to re-sensitize laboratory strains and clinical isolates to last resort antibiotics
Frusteri Chiacchiera, A.; Casanova, M.; Bellato, M.; Piazza, A.; Migliavacca, R.; Batt, G.; Magni, P.; Pasotti, L.
10.1101/2024.07.30.604783 — synthetic biology — Posted on 2024-07-30
243 The structural basis for the selective antagonism of soluble TNF-alpha by shark variable new antigen receptors
Ubah, O. C.; Lake, E. W.; Priyanka, S.; Shi, K.; Moeller, N. H.; Porter, A. J.; Aihara, H.; LeBeau, A. M.; Barelle, C. J.
10.1101/2024.07.30.605874 — pharmacology and toxicology — Posted on 2024-07-30
246 An IL-12 mRNA-LNP adjuvant enhances mRNA-LNP vaccine induced CD8+ T cell responses
Aunins, E. A.; Phan, A. T.; Alameh, M.-G.; Cruz-Morales, E.; Christian, D. A.; Bunkofske, M. E.; Dwivedi, G.; Weissman, D.; Hunter, C. A.
10.1101/2024.07.29.605626 — immunology — Posted on 2024-07-30
247 Passive infusion of an S2-Stem broadly neutralizing antibody protects against SARS-CoV-2 infection and lower airway inflammation in rhesus macaques
Bosinger, S. E.; Edwards, C. T.; Karunakaran, K. A.; Garcia, E.; Beutler, N.; Gagne, M.; Golden, N.; Aoued, H.; Pellegrini, K.; Burnett, M. R.; Honeycutt, C. C.; Lapp, S. A.; Ton, T.; Lin, M. C.; Metz, A.; Bombin, A.; Goff, K.; Scheuermann, S. E.; Wilkes, A.; Wood, J. S.; Ehnert, S.; Weissman, S.; Curran, E. H.; Moore, I. N.; Roy, M.; Dessasau, E.; Paiardini, M.; Upadhyay, A. A.; Maness, N. J.; Douek, D. C.; Piantadosi, A.; Andrabi, R.; Rogers, T. R.; Burton, D. R.
10.1101/2024.07.30.605768 — immunology — Posted on 2024-07-30
248 Immunodominant extracellular loops of Treponema pallidum FadL outer membrane proteins elicit antibodies with opsonic and growth-inhibitory activities
Delgado, K. N.; Caimano, M. J.; Orbe, I. C.; Vicente, C. F.; LaVake, C. J.; Grassmann, A. A.; Moody, M. A.; Radolf, J. D.; Hawley, K. L.
10.1101/2024.07.30.605823 — immunology — Posted on 2024-07-30
251 Cryo-EM Structure of Salmonella typhimurium ArnC; the Key Enzyme in Lipid-A Modification Conferring Polymyxin Resistance
Patel, D. H.; Karimullina, E.; Guo, Y.; Semper, C.; Patel, D. T.; Emde, T.; Borek, D.; Savchenko, A.
10.1101/2024.07.30.605912 — biochemistry — Posted on 2024-07-30
252 Blended Genome Exome (BGE) as a Cost Efficient Alternative to Deep Whole Genomes or Arrays
DeFelice, M.; Grimsby, J.; Howrigan, D.; Yuan, K.; Chapman, S. B.; Stevens, C.; DeLuca, S.; Townsend, M.; Buxbaum, J.; Pericak-Vance, M. A.; Qin, S.; Stein, D. J.; Teferra, S.; Xavier, R.; Huang, H.; Martin, A.; Neale, B.
10.1101/2024.04.03.587209 — genomics — Posted on 2024-07-30
258 Establishing And Maintaining The Blood-Brain Barrier: Epigenetic And Signaling Determinants.
Pandit, P. K. T.; Sadanandan, J.; Thomas, S.; Mathew, I. E.; Huang, Z.; Blackburn, S. L.; Tandon, N.; Lokhande, H.; McCrea, P. D.; Bresnick, E. H.; Dash, P. K.; McBride, D. W.; Harmanci, A.; Ahirwar, L. K.; Jose, D.; Dienel, A. C.; Zeineddine, H. A.; Hong, S.
10.1101/2022.11.29.516809 — neuroscience — Posted on 2024-07-30
259 Clinical prediction of wound re-epithelisation outcomes in non-severe burn injury using the plasma lipidome
Ryan, M. J.; Raby, E.; Masuda, R.; Lodge, S.; Nitschke, P.; Maker, G. L.; Wist, J.; Fear, M. W.; Holmes, E.; Nicholson, J.; Gray, N.; Whiley, L.; Wood, F. M.
10.1101/2023.07.28.550938 — systems biology — Posted on 2024-07-30
260 Remote organ cancer adversely alters renal function and induces kidney injury, inflammation, and fibrosis.
Hammouri, D.; Orwick, A.; Doll, M.; Sanchez Vega, D.; Shah, P. P.; Clarke, C. J.; Clem, B.; Beverly, L. J.; Siskind, L. J.
10.1101/2024.07.29.605635 — physiology — Posted on 2024-07-30
263 Wearable Disposable Electrotherapy
FallahRad, M.; Chaudhry, Z.; Belali Koochesfahani, M.; Bhuiyan, R.; Zaman, M.; Liu, T.; Saha, K.; Diaz Uraga, M. R.; Thahsin, M.; Donnery, K.; Babaev, B.; Saw, M.; Rddad, A.; Velarde, O.; Couzis, A.; Bikson, M.
10.1101/2023.11.28.569062 — bioengineering — Posted on 2024-07-30
264 Molecular insight into the Drosophila piRNA pathway network through a combination of systematic protein interaction screening and structural prediction
Salgania, H. K.; Metz, J.; Lingren, E.; Bleischwitz, C.; Hauser, D.; Oliveras Mate, K.; Bollack, D.; Lahr, F.; Garbelyanski, A.; Jeske, M.
10.1101/2024.05.31.596839 — biochemistry — Posted on 2024-07-30
266 Regulatory T-cells in multiple sclerosis are activated by Epstein-Barr Virus and produce IL-10 in the central nervous system
Pulvirenti, N.; Righetti, C.; Clemente, F.; Serafini, B.; Pietroboni, A.; Galeota, E.; Rosicarelli, B.; Cordiglieri, C.; Iannone, C.; de Riz, M.; Vasco, C.; Espadas de Arias, A.; De Feo, T.; Valenti, L.; Prati, D.; Abrignani, S.; Gerosa, M.; Caporali, R.; Galimberti, D.; Scarpini, E.; Geginat, J.
10.1101/2024.07.30.605745 — immunology — Posted on 2024-07-30
267 ComBatLS: A location- and scale-preserving method for multi-site image harmonization
Gardner, M.; Shinohara, R.; Bethlehem, R. A. I.; Romero Garcia, R.; Warrier, V.; Dorfschmidt, L.; Lifespan Brain Chart Consortium, ; Shanmugan, S.; Thompson, P.; Seidlitz, J.; Alexander-Bloch, A.; Chen, A.
10.1101/2024.06.21.599875 — neuroscience — Posted on 2024-07-30
270 Pigment-dispersing factor neuropeptides act as multifunctional hormones and modulators in tardigrades
Dutta, S.; Hering, L.; Grollmann, M. M.; Metzendorf, N.; Gross, V.; Arakawa, K.; Neupert, S.; Stengl, M.; Herberg, F. W.; Mayer, G.
10.1101/2024.07.30.605422 — zoology — Posted on 2024-07-30
274 Derivation of aerial insect concentration with a 94 GHz FMCW cloud radar
Lochmann, M.; Kalesse-Los, H.; Haest, B.; Vogl, T.; van Klink, R.; Addison, F.; Maahn, M.; Schimmel, W.; Wirth, C.; Quaas, J.
10.1101/2024.07.30.605781 — ecology — Posted on 2024-07-30
275 Structural Basis of betaKNL2 Centromeric Targeting Mechanism and Its Role in Plant-Specific Kinetochore Assembly
Yadala, R.; Camara, A. S.; Yalagapati, S. P.; Jaroschinsky, P.; Meitzel, T.; Ariyoshi, M.; Fukagawa, T.; Rutten, T.; Bui, T. T. G.; Lermontova, I.
10.1101/2024.07.30.605747 — molecular biology — Posted on 2024-07-30
276 The phenotype of SMC6_G514R hinge mutant of Physcomitrium patents
Angelis, K. J.; Hola, M.; Vagnerova, R.; Vaculikova, J.; Palecek, J. J.
10.1101/2024.07.29.605668 — molecular biology — Posted on 2024-07-30
277 The role of the synaptic vesicle protein SV2A in regulating mitochondrial morphology and autophagy.
Joerg, M.; Reichert, J. S.; Pauly, K.; Distler, U.; Tenzer, S.; Bartholome, O.; Rogister, B.; Kern, A.; Behl, C.; Gelleri, M.; Ritz, S.; Cremer, C. M.; Peslalz, P.; Plietker, B.; Friedland, K.
10.1101/2024.07.30.605753 — molecular biology — Posted on 2024-07-30
278 Lasso peptides sviceucin and siamycin I have anti-virulence activity and restore vancomycin effectiveness in vancomycin-resistant Enterococcus sp. and Staphylococcus aureus
Boudrioua, A.; Baëtz, B.; Desmadril, S.; Goulard, C.; Groo, A.-C.; Lombard, C.; Gueulle, S.; Marugan, M.; Malzert-Freon, A.; Hartke, A.; Li, Y.; Giraud, C.
10.1101/2024.07.30.605797 — microbiology — Posted on 2024-07-30
280 Rapid neutralizing assay for circulating H5N1 influenza virus in dairy cows
Miyakawa, K.; Ota, M.; Sano, K.; Momose, F.; Okura, T.; Kishida, N.; Arita, T.; Suzuki, Y.; Shirakura, M.; Asanuma, H.; Watanabe, S.; Ryo, A.; Hasegawa, H.
10.1101/2024.07.30.605731 — microbiology — Posted on 2024-07-30
282 Second impact of an acute total body irradiation on thymic epithelial cells
Namiki, K.; Muramatsu, W.; Miyao, T.; Ishii, H.; Endo, R.; Hagiwara, N.; Miyauchi, M.; Yoshida, M.; Akiyama, N.; Akiyama, T.
10.1101/2024.07.30.605780 — immunology — Posted on 2024-07-30
287 Genome-based discovery of pachysiphine synthases in Tabernaemontana elegans
Lezin, E.; Durand, M.; Birer Williams, C.; Lopez Vazquez, A. L.; Perrot, T.; Gautron, N.; Petrignet, J.; Cuello, C.; Jansen, H.; Magot, F.; Szwarc, S.; Le Pogam, P.; Beniddir, M.; Koudounas, K.; Oudin, A.; St-Pierre, B.; Giglioli-Guivarc'h, N.; Sun, C.; Papon, N.; Krogh Jensen, M.; Dirks, R.; O'Connor, S.; Besseau, S.; Courdavault, V.
10.1101/2024.07.30.605783 — plant biology — Posted on 2024-07-30
288 Water availability determines plant regeneration fates
Kareem, A.; van Wullen, A. K.; Zhang, A.; Walckiers, G.; Fasth, E.; Melnyk, C. W.
10.1101/2024.07.30.605771 — plant biology — Posted on 2024-07-30
291 In silico PK predictions in Drug Discovery: Benchmarking of Strategies to Integrate Machine Learning with Empiric and Mechanistic PK modelling
Walter, M.; Aljayyoussi, G.; Gerner, B.; Rapp, H.; Tautermann, C. S.; Balazki, P.; Skalic, M.; Borghardt, J. M.; Humbeck, L.
10.1101/2024.07.30.605777 — bioinformatics — Posted on 2024-07-30
294 Anisotropic Articular Cartilage Biofabrication based on Decellularized Extracellular Matrix
Puiggali-Jou, A.; Hui, I.; Baldi, L.; Frischknecht, R.; Asadikorayem, M.; Janiak, J.; Chansoria, P.; McCabe, M. C.; Stoddart, M. J.; Hansen, K.; Christman, K. L.; Zenobi, M.
10.1101/2024.07.30.605411 — bioengineering — Posted on 2024-07-30
295 Intraperitoneal programming of tailored CAR macrophages via mRNA-LNP to boost cancer immunotherapy
Gu, K.; Liang, T.; Hu, L.; Zhao, Y.; Ying, W.; Zhang, M.; Chen, Y.; Liang, B.; Lin, X.; Zhang, Y.; Wu, H.; Wang, M.; Zhu, Y.; Wang, W.; Zhang, Y.; Zuo, C.; Du, Z.; Zhang, P.; Song, J.; Liu, X.; Xie, S.; Tan, W.
10.1101/2024.07.30.605730 — bioengineering — Posted on 2024-07-30
296 Chromosome-scale genome assembly of acerola (Malpighia emarginata DC.)
Shirasawa, K.; Harada, K.; Haramoto, N.; Aoki, H.; Kammera, S.; Yamamoto, M.; Nishizawa, Y.
10.1101/2024.07.30.605750 — genomics — Posted on 2024-07-30
298 Regulatory Subfunctionalization drives OXPHOS evolution in teleosts
Tsipourlianos, A.; Cardoso, J. C.; Angelakopoulos, R.; Kotoula, A.; Power, D. M.; Mamuris, Z.; Moutou, K. A.
10.1101/2024.07.30.605748 — evolutionary biology — Posted on 2024-07-30
299 patter: particle algorithms for animal tracking in R and Julia
Lavender, E.; Scheidegger, A.; Albert, C.; Biber, S. W.; Illian, J.; Thorburn, J.; Smout, S.; Moor, H.
10.1101/2024.07.30.605733 — ecology — Posted on 2024-07-30
301 Id2 levels determine the development of effector vs. exhausted tissue-resident memory CD8+ T cells during CNS chronic infection
Coulibaly, A. S. K.; Nozeran, L.; Thomann, C.; Alis, M.; Bassot, E.; Hassan, A.; Porte, R.; Belloy, M.; Blanchard, N.; Masson, F.
10.1101/2024.07.30.605547 — immunology — Posted on 2024-07-30
305 Human-like APOBEC3 gene expression and anti-viral responses following replacement of mouse Apobec3 with the 7-gene human APOBEC3 locus
Kirkwood, N. K.; Prosser, H.; Yap, M. W.; Gibson, J.; Cook, R.; Reddin, I.; Stranger, A.; Howes, E.; Zainal, N.; Periyasamy, M.; Thomas, G. J.; Scott, J.; Bishop, K. N.; Ali, S.; Bradley, A.; Fenton, T. R.
10.1101/2024.07.30.605801 — cancer biology — Posted on 2024-07-30
306 ADAM17 regulates hepatic DNA damage repair and tumour formation
Reichert, M.; Halwachs, B.; Bolik, J.; Senftleben, A.; Krause, F.; Conrady, L.; Bauer, R.; Rachmilewitz, J.; Horejs-Hoeck, J.; Rose-John, S.; Schmidt-Arras, D.
10.1101/2024.07.30.605791 — cancer biology — Posted on 2024-07-30
309 Fast and long-term super-resolution imaging of ER nano-structural dynamics in living cells using a neural network
Balakrishnan, A.; Rahm, J. V.; Wehrheim, M.; Kaminer, A.; Glogger, M.; Kessler, L. F.; Kaschube, M.; Barth, H.-D.; Heilemann, M.
10.1101/2024.07.30.605742 — biophysics — Posted on 2024-07-30
311 Disruption of CAD oligomerization by pathogenic variants
del Cano-Ochoa, F.; Ramadane-Morchadi, L.; Eixeres, L.; Moreno-Morcillo, M.; Fernandez-Leiro, R.; Ramon-Maiques, S.
10.1101/2024.07.30.605799 — biochemistry — Posted on 2024-07-30
316 Ca2+-driven PDIA6 phase separation to ensure proinsulin quality control
Lee, Y.-H.; Saio, T.; Watabe, M.; Matsusaki, M.; Kanemura, S.; Lin, Y.; Mannen, T.; Kuramochi, T.; Iuchi, K.; Tajiri, M.; Suzuki, K.; Li, Y.; Heo, Y.; Kamada, Y.; Arai, K.; Hashimoto, M.; Ninagawa, S.; Hattori, Y.; Kumeta, H.; Takeuchi, A.; Abe, H.; Mori, E.; Muraoka, T.; Okiyoneda, T.; Akashi, S.; Vendruscolo, M.; Inaba, K.; Okumura, M.
10.1101/2024.07.30.605722 — biochemistry — Posted on 2024-07-30
317 The origin of septin ring size control in budding yeast
Kukhtevich, I.; Persson, S.; Padovani, F.; Schneider, R.; Cvijovic, M.; Schmoller, K. M.
10.1101/2024.07.30.605628 — cell biology — Posted on 2024-07-30
319 One to rule them all? Assessing the performance of sustainable forest management indicators against multitaxonomic data for biodiversity conservation
Paillet, Y.; Zapponi, L.; Schall, P.; Monnet, J.-M.; Ammer, C.; Balducci, L.; Boch, S.; Brazaitis, G.; Campanaro, A.; Chianucci, F.; Doerfler, I.; Fischer, M.; Gosselin, M.; Gossner, M. M.; Heilmann-Clausen, J.; Hofmeister, J.; Hosek, J.; Jung, K.; Kepfer-Rojas, S.; Odor, P.; Tinya, F.; Trentanovi, G.; Vacchiano, G.; Vandekerkhove, K.; Weisser, W. W.; Wohlwend, M.; Burrascano, S.
10.1101/2024.02.12.579875 — ecology — Posted on 2024-07-30
321 Epsins oversee smooth muscle cell reprogramming by influencing master regulators KLF4 and OCT4.
Wang, B.; Cui, K.; Zhu, B.; Dong, Y.; Wang, D.; Singh, B.; Wu, H.; Li, K.; Eisa-Beygi, S.; Sun, Y.; Wong, S.; Cowan, D. B.; Chen, Y.; Du, M.; Chen, H.
10.1101/2024.01.08.574714 — cell biology — Posted on 2024-07-30
322 Glucocorticoids desensitize CRH neurons to norepinephrine via rapid nitrosylation-dependent regulation of α1 adrenoreceptor trafficking
Weiss, G. L.; Harrison, L. M.; Jiang, Z.; Nielsen, A. M.; Feygin, M. S.; Nguyen, S.; Tirrell, P. S.; Tasker, J. G.
10.1101/2024.07.29.605704 — neuroscience — Posted on 2024-07-30
325 Evolution and diversification of the momilactone biosynthetic gene cluster in the genus Oryza
Priego Cubero, S.; Toyomasu, T.; Gigl, M.; Liu, Y.; Hasegawa, Y.; Nojiri, H.; Dawid, C.; Okada, K.; Becker, C.
10.1101/2024.01.11.572147 — plant biology — Posted on 2024-07-30
327 The VanS sensor histidine kinase from type-B VRE recognizes vancomycin directly
Maciunas, L. J.; Rotsides, P.; D'Lauro, E. J.; Brady, S.; Beld, J.; Loll, P. J.
10.1101/2023.07.09.548278 — biochemistry — Posted on 2024-07-30
328 Mechanical problem solving in mice
Boon, M. N.; Andresen, N.; Traverso, S.; Meier, S.; Schuessler, F.; Hellwich, O.; Lewejohann, L.; Thöne-Reineke, C.; Sprekeler, H.; Hohlbaum, K.
10.1101/2024.07.29.605658 — animal behavior and cognition — Posted on 2024-07-30
329 Novel Approach for Refractive Index Matching in Calcified Tissues
Laudier, D.; Mora-Antionette, M.; Garcia-Ortiz, A.; Lewis, K. J.
10.1101/2024.07.23.604611 — cell biology — Posted on 2024-07-30
331 Gustatory Thalamic Neurons Mediate Aversive Behaviors
Cao, F.; Park, S.; Pauli, J. L.; Seo, E. Y.; Palmiter, R. D.
10.1101/2024.07.29.605702 — neuroscience — Posted on 2024-07-30
335 Harnessing genome prediction in Brassica napus through a nested association mapping population
Perumal, S.; Higgins, E.; Sra, S.; Khedikar, Y.; Moore, J.; Chaudhary, R.; Haile, T.; Koh, C. S.; Vail, S.; Robinson, S. J.; Horner, K. N.; Hope, B.; Klein-Gebbinck, H.; Herrmann, D.; Navabi, Z.-K.; Sharpe, A. G.; Parkin, I. A. P.
10.1101/2024.07.29.604859 — genomics — Posted on 2024-07-30
337 Change in functional trait diversity mediates the effects of nutrient addition on grassland stability
Chen, Q.; Wang, S.-P.; Seabloom, E. W.; Isbell, F.; Borer, E. T.; Bakker, J. D.; Bharath, S.; Roscher, C.; Peri, P. L.; Power, S. A.; Donohue, I.; Stevens, C.; Ebeling, A.; Nogueira, C.; Caldeira, M. C.; MacDougall, A.; Moore, J.; Bagchi, S.; Jentsch, A.; Tedder, M.; Kirkman, K.; Alberti, J.; Hautier, Y.
10.1101/2022.09.16.508233 — ecology — Posted on 2024-07-30
338 Deletion of Setd7 protects against cardiac hypertrophy via inhibiting lipid oxidation
Su, H.; Wang, J.; Zhang, Y.; Xu, J.; Liu, J.; Li, Y.; Xiao, C.; Wang, C.; Chang, J.; Liu, X.
10.1101/2024.07.29.605718 — molecular biology — Posted on 2024-07-30
339 Nutrition induced changes in the microbiota can cause dysbiosis and disease development
Lachnit, T.; Ulrich, L.; Willmer, F. M.; Hasenbein, T.; Steiner, L. X.; Wolters, M.; Herbst, E. M.; Deines, P.
10.1101/2024.07.29.605727 — microbiology — Posted on 2024-07-30
340 Cell binding, uptake and infection of influenza A virus using recombinant antibody-based receptors.
Adu, O. F.; Sempere Borau, M.; Frueh, S. P.; Karakus, U.; Weichert, W.; Wasik, B. R.; Stertz, S.; Parrish, C. R.
10.1101/2024.07.29.605726 — microbiology — Posted on 2024-07-30
341 An IL-12 mRNA-LNP adjuvant enhances mRNA-LNP vaccine induced CD8+ T cell responses
Aunins, E. A.; Phan, A. T.; Alameh, M.-G.; Cruz-Morales, E.; Christian, D. A.; Bunkofske, M. E.; Dwivedi, G.; Weissman, D.; Hunter, C.
10.1101/2024.07.29.605626 — immunology — Posted on 2024-07-30
342 Visual to default network pathways: A double dissociation between semantic and spatial cognition
Gonzalez Alam, T. R.; Krieger-Redwood, K.; Varga, D.; Gao, Z.; Horner, A. R.; Hartley, T.; Thiebaut de Schotten, M.; Sliwinska, M. W.; Pitcher, D.; Margulies, D. S.; Smallwood, J.; Jefferies, E.
10.1101/2023.11.28.568861 — neuroscience — Posted on 2024-07-30
343 Model of a striatal circuit exploring biological mechanisms underlying decision-making during normal and disordered states
Beck, D. W.; Heaton, C. N.; Davila, L. D.; Rakocevic, L. I.; Drammis, S. M.; Tyulmankov, D.; Vara, P.; Giri, A.; Umashankar Beck, S.; Zhang, Q.; Pokojovy, M.; Negishi, K.; Batson, S. A.; Salcido, A. A.; Reyes, N. F.; Macias, A. Y.; Ibanez-Alcala, R. J.; Hossain, S. B.; Waller, G. L.; O'Dell, L. E.; Moschak, T. M.; Goosens, K. A.; Friedman, A.
10.1101/2024.07.29.605535 — neuroscience — Posted on 2024-07-30
345 Integrative, high-resolution analysis of single cells across experimental conditions with PARAFAC2
Ramirez, A.; Orcutt-Jahns, B. T.; Pascoe, S.; Abraham, A.; Remigio, B.; Thomas, N.; Meyer, A. S.
10.1101/2024.07.29.605698 — systems biology — Posted on 2024-07-30
346 Deciphering the transcriptional regulatory network of Yarrowia lipolytica using machine learning
Kerssemakers, A. A. J.; Krishnan, J.; Rychel, K.; Zielinski, D. C.; Palsson, B.; Sudarsan, S.
10.1101/2024.07.29.605545 — systems biology — Posted on 2024-07-30
349 Efficient in situ epitope tagging of rice genes by nuclease-mediated prime editing
Li, X.; Zhang, S.; Wang, C.; Ren, B.; Yan, F.; Li, S.; Spetz, C.; Huang, J.; Zhou, X.; Zhou, H.
10.1101/2024.07.29.605657 — plant biology — Posted on 2024-07-30
351 Stromal KITL/SCF promotes pancreas tissue homeostasis and restrains tumor progression
Onate, M. K.; Oon, C.; Bhattacharyya, S.; Low, V.; Chen, C.; Zhao, X.; Yan, Z.; Hang, Y.; Kim, S. K.; Xia, Z.; Sherman, M. H.
10.1101/2024.07.29.605485 — cancer biology — Posted on 2024-07-30
352 Amyloid peptide - synthetic polymer blends with enhanced mechanical and biological properties
Wang, X.; Mondal, M.; Jankoski, P. E.; Kemp, L. K.; Clemons, T. D.; Rangachari, V.; Morgan, S. E.
10.1101/2024.07.29.605712 — biophysics — Posted on 2024-07-30
355 PCA-based spatial domain identification with state-of-the-art performance
Schaub, D. P.; Yousefi, B.; Kaiser, N.; Khatri, R.; Puelles, V. G.; Krebs, C. F.; Panzer, U.; Bonn, S.
10.1101/2024.07.29.605550 — bioinformatics — Posted on 2024-07-30
357 Calcium phosphate nanoclusters modify periodontium remodeling and minimize orthodontic relapse
Cuylear, D. L.; Fu, M. L.; Chau, J. C.; Kharbikar, B.; Kazakia, G.; Jheon, A.; Habelitz, S.; Kapila, S. D.; Desai, T. A.
10.1101/2024.07.29.605671 — bioengineering — Posted on 2024-07-30
361 Appendage regeneration requires IMPDH2 and creates a sensitized environment for enzyme filament formation
McCartney, M. E.; Wheeler, G. M.; O'Neill, A. G.; Patel, J. H.; Litt, Z. R.; Calise, S. J.; Kollman, J. M.; Wills, A. E.
10.1101/2024.07.29.605679 — developmental biology — Posted on 2024-07-30
362 Long-lived chondroprogenitors are generated by fetal-limb Gli1+ cells and are replenished upon mosaic cell-cycle arrest in the cartilage
Qu, X.; Razmara, E.; H'ng, C. H.; Vinu, K. K.; Martelotto, L. G.; Zethoven, M.; Rossello, F. J.; Johnstone, R. W.; Amarasinghe, S. L.; Powell, D. R.; Rosello-Diez, A.
10.1101/2024.07.29.603524 — developmental biology — Posted on 2024-07-30
365 Effects of two different compounds on seizure suppression using the zebrafish PTZ-seizure model
Fernandez, J. A. A.; de Moura, T. C.; Vila, S. F.; Gaytan, J. A. R.; Lopez-Diaz, I.; Learte-Aymami, S.; Vazquez, M. E.; Mayan, M. D.; Sanchez, L.; Maurer-Morelli, C. V.
10.1101/2024.07.29.605666 — neuroscience — Posted on 2024-07-30
366 Pervasive neurovascular dysfunction in the ventromedial prefrontal cortex of female depressed suicides with a history of childhood abuse
Wakid, M.; Almeida, D.; Denniston, R.; Chawla, A.; Aouabed, Z.; Davoli, M. A.; Rahimian, R.; Ellerbeck, K.; Yerko, V.; Leonova-Erko, E.; Turecki, G.; Mechawar, N.
10.1101/2024.07.29.605502 — neuroscience — Posted on 2024-07-30
369 Ototoxicity-related Changes in GABA Immunolabeling Within the Rat Inferior Colliculus
Holt, A. G.; Griffith, R. D.; Lee, S. D.; Asako, M.; Buras, E.; Yalcinoglu, S.; Altschuler, R. A.
10.1101/2024.07.29.603150 — neuroscience — Posted on 2024-07-30
373 K-mer Genome-wide Association Study for Anthracnose and BCMV Resistance in the Andean Diversity Panel
Wiersma, A.; Hamilton, J. P.; Vaillanoucrt, B.; Brose, J.; Awale, H. E.; Wright, E. M.; Kelly, J. D.; Buell, C. R.
10.1101/2024.07.29.605481 — plant biology — Posted on 2024-07-30
374 Remote organ cancer adversely alters renal function and induces kidney injury, inflammation, and fibrosis.
Hammouri, D.; Orwick, A.; Doll, M.; Sanchez Vega, D.; Shah, P. P.; Clarke, C. J.; Clem, B.; Beverly, L. J.; Siskind, L. J.
10.1101/2024.07.29.605635 — physiology — Posted on 2024-07-30
376 Subtypes and proliferation patterns of small intestine neuroendocrine tumors revealed by single cell RNA sequencing
Somech, E.; Halder, D.; Spitzer, A.; Barbolin, C.; Tyler, M.; Halperin, R.; Biton, M.; Tirosh, A.; Tirosh, I.
10.1101/2024.07.29.605642 — cancer biology — Posted on 2024-07-30
377 Senescent fibroblasts in the tumor stroma rewire lung cancer metabolism and plasticity
Lee, J.; Nabora, S. R.; Woo, S.-H.; Goel, S.; Stratton, F.; Kuang, C.; Mansfield, A.; LaFave, L.; Peng, T.
10.1101/2024.07.29.605645 — cancer biology — Posted on 2024-07-30
380 Collective flow of circadian clock information in honeybee colonies
Mellert, J.; Kłos, W.; Dormagen, D. M.; Wild, B.; Zachariae, A.; Smith, M. L.; Galizia, C. G.; Landgraf, T.
10.1101/2024.07.29.605620 — animal behavior and cognition — Posted on 2024-07-30
381 Genetic diversity analysis of main agronomic traits and ISSR markers in 35 ornamental rape germplasm resources
Xia, M.; Chen, M.; Dong, X.; Chen, M.; Chen, J.; Wang, H.; Dong, Y.; Zeng, C.; Dai, X.; Meizhu Chen,Xiaoxiao Dong, Jingdong Chen, Miao Cheng, Heping Wan, Yuanhuo Dong, Changli Zeng and Xig,
10.1101/2024.07.29.605676 — genetics — Posted on 2024-07-30
382 Cathelicidin antimicrobial peptides mediate immune protection of marsupial neonates
Park, J.; Ke, W.; Kaage, A.; Feigin, C. Y.; Pritykin, Y.; Donia, M. S.; Mallarino, R.
10.1101/2024.07.29.605640 — evolutionary biology — Posted on 2024-07-30
383 CIB2 as a Ca2+ Sensor for Auditory Mechano-Electrical Transduction and Linked to Genetic-Heterogeneity of TMC1 in Hearing Loss
Wu, S.; Lin, L.; Hu, Q.; Yao, X.; Wang, H.; Liu, S.; Liu, Q.; Xi, Y.; Lin, Y.; Gong, J.; Hu, R.; Zhan, W.; Luo, Y.; He, G.; Liu, Z.; Xiong, W.; Wang, Q.; Xu, Z.; Bai, F.; Lu, Q.
10.1101/2024.07.24.604958 — molecular biology — Posted on 2024-07-30
384 On the mode of anti-C. albicans activity of a bis(benzoxaborole) analogue of Tavaborole
Gadakh, S.; Szczepinska, T.; Potoczna, M.; Sakutayama, S. O.; Podlasz, P.; Rogalska, M.; Kaczorowska, E.; Adamczyk-Wozniak, A.; Staniszewska, M.
10.1101/2024.07.29.605614 — microbiology — Posted on 2024-07-30
387 Three Dimensional Multiscalar Neurovascular Nephron Connectivity Map of the Human Kidney Across the Lifespan
McLaughlin, L.; Zhang, B.; Sharma, S.; Knoten, A. L.; Kaushal, M.; Purkerson, J. M.; Huyck, H.; Pryhuber, G. S.; Gaut, J. P.; Jain, S.
10.1101/2024.07.29.605633 — neuroscience — Posted on 2024-07-30
388 Chemical genetics reveals cross-activation of plant developmental signaling by the immune peptide-receptor pathway
Herrmann, A.; Sepuru, K. M.; Endo, H.; Nakagawa, A.; Kusao, S.; Bai, P.; Ziadi, A.; Kato, H.; Sato, A.; Liu, J.; Shan, L.; Kimura, S.; Itami, K.; Uchida, N.; Hagihara, S.; Torii, K. U.
10.1101/2024.07.29.605519 — plant biology — Posted on 2024-07-30
390 A trimeric USP11/USP7/TCEAL1 complex stabilizes RNAPII during early transcription to sustain oncogenic gene expression
Dehmer, M.; Gallant, P.; Herold, S.; Cossa, G.; Conte, F.; Koster, J.; Sauer, F.; Schuelein-Voelk, C.; Ade, C. P.; Vidal, R.; Kisker, C.; Versteeg, R.; Beli, P.; Vos, S.; Eilers, M.; Buechel, G.
10.1101/2024.07.29.605622 — cancer biology — Posted on 2024-07-30
391 Resolving the Structure of a Guanine Quadruplex in TMPRSS2 Messenger RNA by Circular Dichroism and Molecular Modeling
D'Anna, L.; Froux, A.; Rainot, A.; Spinello, A.; Perricone, U.; Barbault, F.; Grandemange, S.; Barone, G.; Terenzi, A.; Monari, A.
10.1101/2024.07.29.605618 — biophysics — Posted on 2024-07-30
393 Explicit description of viral capsid subunit shapes by unfolding dihedrons
Toyooka, R.; Nishimoto, S.; Tendo, T.; Horiyama, T.; Tachi, T.; Matsunaga, Y.
10.1101/2024.07.29.605617 — biophysics — Posted on 2024-07-30
395 Machine Learning Uncovers the Transcriptional Regulatory Network for the Production Host Streptomyces albidoflavus
Jönsson, M.; Sigrist, R.; Gren, T.; Semenov Petrov, M.; Marcussen, N.; Svetlova, A.; Charusanti, P.; Gockel, P.; Palsson, B. O.; Yang, L.; Özdemir, E.
10.1101/2024.01.09.574332 — genomics — Posted on 2024-07-30
396 Impact of preanalytical factors on liquid biopsy in the canine cancer model
Megquier, K.; Husted, C.; Rhoades, J.; White, M. E.; Genereux, D. P.; Chen, F. L.; Xiong, K.; Kwon, E.; Swofford, R.; Painter, C.; Adalsteinsson, V.; London, C. A.; Gardner, H. L.; Karlsson, E. K.
10.1101/2024.07.29.605605 — genomics — Posted on 2024-07-30
400 Sepsis-induced NET formation requires MYD88 but is independent of GSDMD and PAD4
Renne, T.; Englert, H.; Rangaswamy, C.; Divivier, M.; Göbel, J.; Hermans-Borgmeyer, I.; Borgmeyer, U.; Mowen, K. A.; Beerens, M.; Frye, M.; Mailer, R. K.; Gelderblom, M.; Stavrou, E.; Preston, R. J.; Schneider, S. W.; Fuchs, T. A.
10.1101/2024.07.29.605563 — immunology — Posted on 2024-07-30
401 Limiting mitochondrial-derived ATP transfer to the cytosol enhances T-cell activation
Yosef, O.; Cohen-Daniel, L.; Shamriz, O.; Bar-On, Z.; Saragovi, A.; Abramovich, I.; Agranovich, B.; Lutz, V.; Tam, J.; Permyakova, A.; Gottlieb, E.; Huber, M.; Berger, M.
10.1101/2024.04.21.590436 — immunology — Posted on 2024-07-30
403 Calcium-independent lipid release from astrocytes modulates neuronal excitability
Wang, F.; Bradshaw, H. B.; Jablonska, B.; Pena, S. E.; Chittaranjan, S.; Xavier, J.; Gong, S.; Li, B.; Chandler-Militello, D.; Bekar, L. K.; Smith, N. A.
10.1101/2020.01.12.903393 — neuroscience — Posted on 2024-07-30
404 Structural diversity of mitochondria in the neuromuscular system across development
Bae, J. A.; Choi, M.-k.; Ahn, S.; Ko, G.; Choe, D. T.; Yim, H.; Nguyen, K. C. Q.; Kim, J. S.; Hall, D. H.; Lee, J.
10.1101/2024.07.19.604219 — neuroscience — Posted on 2024-07-30
405 DNA damage response signatures are associated with frontline chemotherapy response and routes of tumor evolution in extensive stage small cell lung cancer
Morris, B. B.; Heeke, S.; Xi, Y.; Diao, L.; Wang, Q.; Rocha, P.; Arriola, E.; Lee, M. C.; Tyson, D. R.; Concannon, K.; Ramkumar, K.; Stewart, C. A.; Cardnell, R. J.; Wang, R.; Quaranta, V.; Wang, J.; Heymach, J. V.; Nabet, B. Y.; Shames, D. S.; Gay, C. M.; Byers, L. A.
10.1101/2024.07.29.605595 — cancer biology — Posted on 2024-07-30
407 Using flux theory in dynamic omics data sets to identify differentially changing signals using DPoP
Edwards, H.; Zavorskas, J.; Huso, W.; Doan, A. G.; Silbiger, C.; Harris, S.; Srivastava, R.; Marten, M. R.
10.1101/2024.07.29.605590 — bioinformatics — Posted on 2024-07-30
408 Paternal genome elimination creates contrasting evolutionary trajectories in male and female citrus mealybugs
Mongue, A. J.; Woodman, T.; Marshall, H.; Garber, A. J.; Franco, J. C.; McCutcheon, J. P.; Ross, L.
10.1101/2024.07.28.604693 — evolutionary biology — Posted on 2024-07-30
411 Latent mitotic vulnerability of AML cells induced by therapeutic agents
Niikura, R.; Yabushita, T.; Yamamoto, S.; Suzuki, H.; Fukuyama, M.; Hata, S.; Goyama, S.; Kitamura, T.; Chinen, T.; Kitagawa, D.
10.1101/2024.06.27.600939 — cancer biology — Posted on 2024-07-30
413 TissueViewer: A Web-Based Multiplexed Image Viewer
van IJzendoorn, D. G. P.; Matusiak, M.; West, R. B.; van de Rijn, M.
10.1101/2024.06.21.600100 — bioinformatics — Posted on 2024-07-30
414 Enhancing the Reverse Transcriptase Function in Taq Polymerase via AI-driven Multiparametric Rational Design
Tomilova, Y. E.; Russkikh, N. E.; Yi, I. M.; Shaburova, E. V.; Tomilov, V. N.; Pyrinova, G. B.; Brezhneva, S. O.; Tikhonyuk, O. S.; Gololobova, N. S.; Popichenko, D. V.; Arkhipov, M. O.; Bryzgalov, L. O.; Brenner, E. V.; Artyukh, A. A.; Shtokalo, D. N.; Antonets, D. V.; Ivanov, M. K.
10.1101/2024.07.24.604875 — bioengineering — Posted on 2024-07-30
417 Functional networks of inhibitory neurons orchestrate synchrony in the hippocampus
Bocchio, M.; Vorobyev, A.; Sadeh, S.; Brustlein, S.; Dard, R.; Reichinnek, S.; EMILIANI, V.; Baude, A.; Clopath, C.; Cossart, R.
10.1101/2023.09.18.558335 — neuroscience — Posted on 2024-07-30
421 Efficient generation of CAR NK cells from human umbilical cord blood CD34+ stem and progenitors for democratizing affordable immunotherapy
Li, J.; Wang, Y.; Zheng, X.; Lin, Y.; Weng, Q.; Liu, X.; Geng, Y.; Wu, H.; Liu, L.; Peng, H.; Wu, B.; Huang, D.; Xia, C.; Wang, T.; Zhang, M.; Du, X.; Zeng, H.; Dong, F.; Zhang, Y.; Zhu, X.; Hu, F.; Wang, J.
10.1101/2024.07.30.605741 — cell biology — Posted on 2024-07-30
427 Multiscale mechanics drive functional maturation of the vertebrate heart
Andrews, T. G.; Cornwall Scoones, J.; Ramel, M.-C.; Gupta, K.; Briscoe, J.; Priya, R.
10.1101/2024.07.24.604962 — developmental biology — Posted on 2024-07-30
428 White matter connections of human ventral temporal cortex are organized by cytoarchitecture, eccentricity, and category-selectivity from birth
Kubota, E.; Yan, X.; Tung, S.; Fascendini, B.; Tyagi, C.; Duhameau, S.; Ortiz, D.; Grotheer, M.; Natu, V. S.; Keil, B.; Grill-Spector, K.
10.1101/2024.07.29.605705 — neuroscience — Posted on 2024-07-30
429 Unravelling the neurocognitive mechanisms underlying counterconditioning in humans
Wirz, L.; Houtekamer, M. C.; de Vos, J.; Dunsmoor, J. E.; Homberg, J.; Henckens, M. J. A. G.; Hermans, E.
10.1101/2024.07.29.605706 — neuroscience — Posted on 2024-07-30
430 Galanin receptor 1 expressing neurons in hippocampal-prefrontal circuitry modulate goal directed attention and impulse control
Messanvi, F.; Visocky, V.; Senneca, C.; Berkun, K.; Taori, M.; Bradley, S. P.; Wang, H.; Tejeda, H.; Chudasama, Y.
10.1101/2024.07.29.605653 — neuroscience — Posted on 2024-07-30
431 Multimodal weakly supervised learning to identify disease-specific changes in single-cell atlases
Litinetskaya, A.; Shulman, M.; Hediyeh-zadeh, S.; Moinfar, A. A.; Curion, F.; Szalata, A.; Omidi, A.; Lotfollahi, M.; Theis, F. J.
10.1101/2024.07.29.605625 — bioinformatics — Posted on 2024-07-29
433 Conservation, alteration, and redistribution of mammalian striatal interneurons
Corrigan, E. K.; DeBerardine, M.; Poddar, A.; Turrero Garcia, M.; Schmitz, M. T.; Harwell, C.; Paredes, M.; Krienen, F. M.; Pollen, A. A.
10.1101/2024.07.29.605664 — evolutionary biology — Posted on 2024-07-30
438 Oxidation of Four Monoterpenoid Indole Alkaloid Classes by Three Cytochrome P450 Monooxygenases from Tabernaemontana litoralis
Mai, Z.; Kim, K.; Richardson, M. B.; Deschenes, D. A. R.; Garza-Garcia, J. J. O.; Shahsavarani, M.; Perley, J. O.; Njoku, D. I.; Deslongchamps, G.; De Luca, V.; Qu, Y.
10.1101/2024.07.29.605674 — biochemistry — Posted on 2024-07-29
441 Histones are exosome membrane proteins regulated by cell stress
Singh, B.; Sundbom, M. F.; Muthukrishnan, U.; Natarajan, B.; Stransky, S.; Nordin, J. Z.; Wiklander, O. P. B.; Sandblad, L.; Sidoli, S.; EL Andaloussi, S.; Haney, M.; Gilthorpe, J. D.
10.1101/2024.04.08.588575 — cell biology — Posted on 2024-07-29
442 Identification and functional validation of human islet microRNAs associated with donor trait
Wong, W. K.; El-Azzi, I.; Nachanekar, A.; Alvandi, E.; Pham, N. H.; Sara, M.; Cheng, F.; Jiang, G.; Sorensen, A. E.; Chew, Y. V.; Loudovaris, T.; Thomas, H. E.; Ma, R. C.; Hawthorne, W. J.; Dalgaard, L. T.; Joglekar, M. V.; Hardikar, A. A.
10.1101/2022.10.14.512222 — cell biology — Posted on 2024-07-29
443 Enhanced RNAi does not provide efficient innate antiviral immunity in mice in vivo.
Kulmann, M. I. R.; Taborska, E.; Benkoova, B.; Palus, M.; Drobek, A.; Horvat, F.; Pasulka, J.; Malik, R.; Sakyova, E.; Honig, V.; Pellerova, M.; Borsanyiova, M.; Stepanek, O.; Bopegamage, S.; Ruzek, D.; Svoboda, P.
10.1101/2024.07.29.605661 — molecular biology — Posted on 2024-07-29
444 Myocardial infarction injury is exacerbated by nicotine in vape aerosol exposure
Savko, C.; Molinaro, C.; Esquer, C.; Rokaw, S.; Shain, A.; Jaafar, F.; Wright, M.; Phillips, J.; Hopkins, T.; Mikhail, S.; Rieder, A.; Mardani, A.; Bailey, B.; Sussman, M.
10.1101/2024.07.29.605355 — molecular biology — Posted on 2024-07-29
445 Tuning of ribosome levels mediated by RNase I and hibernating ribosomes
Minami, A.; Tanzawa, T.; Yang, Z.; Funatsu, T.; Kuzuyama, T.; Yoshida, H.; Kato, T.; Ogawa, T.
10.1101/2024.07.29.605612 — molecular biology — Posted on 2024-07-29
449 Pulsed blue light and phage therapy: A novel synergistic bactericide
Rimon, A.; Belin, J.; Yerushalmy, O.; Alkalay-Oren, S.; Eavri, Y.; Shapochnikov, A.; Coppenhagen-Glazer, S.; Hazan, R.; Gavish, L.
10.1101/2024.07.29.605651 — microbiology — Posted on 2024-07-29
454 Effect of curcumin and 5-bromoindole-3-carboxyaldehyde on the inhibition of Quorum sensig-dependent virulence factors in Pseudomonas aeruginosa
Gonzalez, G. M.; Garcia-Contreras, R.; Garcia Vales, I.; Valdes, N. G.; Lugo Gutierrez, D. A.; Bustamante Martinez, I. L.; Almeida, J.
10.1101/2024.07.29.605599 — microbiology — Posted on 2024-07-29
455 TMPRSS2 activation of Omicron lineage Spike glycoprotein is regulated by Collectrin-like domain of ACE2
Aggarwal, A.; Fichter, C.; Milogiannakis, V.; Ison, T.; Ruiz Silva, M.; Esneau, C.; Bartlett, N.; Burrell, L.; Patel, S.; Churchill, M.; Angelovich, T.; Parry, R.; Sng, J. D.; Neely, G. G.; Moreno, C. L.; Loo, L.; Kelleher, A. D.; Brilot, F.; Khromykh, A.; Turville, S. G.
10.1101/2023.09.22.558930 — microbiology — Posted on 2024-07-29
457 Pan-cortical cellular imaging in freely behaving mice using a miniaturized micro-camera array microscope (mini-MCAM)
Hu, J.; Cherkkil, A.; Surinach, D. A.; Oladepo, I.; Hossain, R. F.; Fausner, S.; Saxena, K.; Ko, E.; Peters, R.; Feldkamp, M.; Konda, P. C.; Pathak, V.; Horstmeyer, R.; Kodandaramaiah, S. B.
10.1101/2024.07.04.601964 — neuroscience — Posted on 2024-07-29
459 Widespread Autonomic Physiological Coupling Across the Brain-Body Axis
Bolt, T. S.; Wang, S.; Nomi, J. S.; Setton, R.; Gold, B.; Frederick, B.; Chen, J. J.; Picchioni, D.; Spreng, R. N.; Keilholz, S.; Uddin, L.; Chang, C.
10.1101/2023.01.19.524818 — neuroscience — Posted on 2024-07-29
462 DNA O-MAP uncovers the molecular neighborhoods associated with specific genomic loci
Liu, Y.; McGann, C. D.; Krebs, M.; Perkins, T. A.; Fields, R.; Camplisson, C. K.; Nwizugbo, D. Z.; Hsu, C.; Avanessian, S.; Tsue, A. F.; Kania, E. E.; Shechner, D. M.; Beliveau, B. J.; Schweppe, D. K.
10.1101/2024.07.24.604987 — systems biology — Posted on 2024-07-29
463 Neuronal expression of human amyloid-β and Tau drives global phenotypic and multi-omic changes in C. elegans
Holcom, A.; Fuentealba, M.; Sivapatham, R.; King, C. D.; Osman, H.; Foulger, A.; Bhaumik, D.; Schilling, B.; Furman, D.; Andersen, J. K.; Lithgow, G. J.
10.1101/2023.06.01.542377 — systems biology — Posted on 2024-07-29
464 Haptoglobin and glutamine synthetase may biomark cachexia induced by anti-acute myeloid leukemia chemotherapy
Campelj, D. G.; Timpani, C. A.; Spiesberger, G.; Formosa, L. E.; Steele, J.; Zhang, H.; Schittenhelm, R. B.; Leow, L.; Goodman, C.; Rybalka, E.
10.1101/2024.07.24.604689 — physiology — Posted on 2024-07-29
467 ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1
Rincon-Torroella, J.; Dal Molin, M.; Mog, B.; Han, G.; Watson, E.; Wyhs, N.; Ishiyama, S.; Ahmedna, T.; Minn, I.; Azad, N. S.; Bettegowda, C.; Papadopoulos, N.; Kinzler, K. W.; Zhou, S.; Vogelstein, B.; Gabrielson, K. L.; Sur, S.
10.1101/2023.07.23.550207 — cancer biology — Posted on 2024-07-29
468 CK2 signaling from TOLLIP-dependent perinuclear endosomes is an essential feature of KRAS and NRAS mutant cancers
Basu, S.; Luke, B.; Karim, B.; Martin, N.; Lockett, S.; Das, S.; Andresson, T.; Saylor, K.; Kozlov, S.; Bassel, L.; Esposito, D.; Galloux, M.; Johnson, P. F.
10.1101/2022.04.05.487175 — cancer biology — Posted on 2024-07-29
469 Development of AI-assisted microscopy frameworks through realistic simulation in pySTED
Bilodeau, A.; Michaud-Gagnon, A.; Chabbert, J.; Turcotte, B.; Heine, J.; Durand, A.; Lavoie-Cardinal, F.
10.1101/2024.03.25.586697 — bioinformatics — Posted on 2024-07-29
471 Reference Sequence Browser: An R application with a User-Friendly GUI to rapidly query sequence databases
Ramesh, S.; Rapp, S. L.; Tapias Gomez, J.; Levine, B.; Tapias-Gomez, D.; Chung, D.; Truong, Z.
10.1101/2023.09.20.558722 — bioinformatics — Posted on 2024-07-29
472 Nonenzymatic, prebiotic aminoacylation couples chirality of RNA and protein
Davisson, J. A.; Kalb, E. M.; Knudson, I. J.; Schepartz, A.; Engelhart, A. E.; Adamala, K.
10.1101/2024.07.29.605638 — biochemistry — Posted on 2024-07-29
473 Fast Targeted Metabolomics for Analyzing Metabolic Diversity of Bacterial Indole Derivatives in ME/CFS Gut Microbiome
Tian, H.; Wang, L.; Aiken, E.; Ortega, R. J. V.; Hardy, R.; Placek, L.; Kozhaya, L.; Unutmaz, D.; Oh, J.; Yao, X.
10.1101/2024.07.29.605643 — biochemistry — Posted on 2024-07-29
476 Phylogenomics resolves the relationship and the evolutionary history of planthoppers (Insecta: Hemiptera: Fulgoromorpha)
Deng, J.; Stroinski, A.; Szwedo, J.; Ghanavi, H. R.; Yapar, E.; Franco, D. C.; Prus-Frankowska, M.; Michalik, A.; Wahlberg, N.; Lukasik, P.
10.1101/2024.07.26.605304 — evolutionary biology — Posted on 2024-07-29
480 The valine-arginine dipeptide repeat protein encoded by mammalian telomeric RNA appears highly expressed in mitosis and may repress global translation
Al-Turki, T.; Mantri, V.; Willcox, S.; Mills, C. A.; Herring, L. E.; Cho, S.-j.; Lee, H.; meyer, C.; Anton, E.; Griffith, J. D.
10.1101/2024.07.24.604971 — molecular biology — Posted on 2024-07-29
481 ComBatLS: A location- and scale-preserving method for multi-site image harmonization
Gardner, M.; Shinohara, R.; Bethlehem, R. A. I.; Romero Garcia, R.; Warrier, V.; Dorfschmidt, L.; Lifespan Brain Chart Consortium, ; Shanmugan, S.; Thompson, P.; Seidlitz, J.; Alexander-Bloch, A.; Chen, A.
10.1101/2024.06.21.599875 — neuroscience — Posted on 2024-07-29
483 Hemispheric difference of adaptation lifetime in human auditory cortex measured with MEG
Dar, A. H.; Haertwich, N.; Hajizadeh, A.; Brosch, M.; Koenig, R.; May, P. J. C.
10.1101/2024.04.16.588236 — neuroscience — Posted on 2024-07-29
484 Trait Reward Sensitivity Modulates Connectivity with the Temporoparietal Junction and Anterior Insula during Strategic Decision Making
Sazhin, D.; Wyngaarden, J. B.; Dennison, J. B.; Zaff, O.; Fareri, D.; McCloskey, M. S.; Alloy, L. B.; Jarcho, J. M.; Smith, D. V.
10.1101/2023.10.19.563125 — neuroscience — Posted on 2024-07-29
486 Increasing spectral DCM flexibility and speed by leveraging Julia's ModelingToolkit and automated differentiation
Hofmann, D.; Chesebro, A. G.; Rackauckas, C.; Mujica-Parodi, L. R.; Friston, K.; Edelman, A.; Strey, H. H.
10.1101/2023.10.27.564407 — neuroscience — Posted on 2024-07-29
487 improv: A software platform for real-time and adaptive neuroscience experiments
Draelos, A.; Loring, M. D.; Nikitchenko, M.; Sriworarat, C.; Gupta, P.; Sprague, D. Y.; Pnevmatikakis, E.; Giovannucci, A.; Benster, T.; Deisseroth, K.; Pearson, J. M.; Naumann, E. A.
10.1101/2021.02.22.432006 — neuroscience — Posted on 2024-07-29
492 NEW INSIGHTS INTO THE HEPATIC IRON PHENOTYPE OF BMP6 KNOCKOUT MICE
BESSON, C.; WILLEMETZ, A.; LATOUR, C.; ROBERT, L.; COPPIN, H.; ROTH, M.-P.; CANONNE-HERGAUX, F.
10.1101/2023.09.28.559941 — pathology — Posted on 2024-07-29
495 Digital Microbe: A Genome-Informed Data Integration Framework for Collaborative Research on Emerging Model Organisms
Veseli, I.; DeMers, M. A.; Cooper, Z. S.; Schechter, M. S.; Miller, S.; Weber, L.; Smith, C. B.; Rodriguez, L. T.; Schroer, W. F.; McIlvin, M. R.; Lopez, P. Z.; Saito, M.; Dyhrman, S.; Eren, A. M.; Moran, M. A.; Braakman, R.
10.1101/2024.01.16.575828 — bioinformatics — Posted on 2024-07-29
496 An Alignment-free Method for Phylogeny Estimation using Maximum Likelihood
Zahin, T.; Abrar, M. H.; Rahman, M.; Tasnim, T.; Bayzid, M. S.; Rahman, A.
10.1101/2019.12.13.875526 — bioinformatics — Posted on 2024-07-29
499 Widely dispersed clonal expansion of multi-fungicide-resistant Aspergillus fumigatus limits genomic epidemiology prospects
Snelders, E.; Celia-Sanchez, B. N.; Nederlof, Y. C.; Zhang, J.; Kortenbosch, H. H.; Zwaan, B. J.; Tehupeiory-Kooreman, M.; Giraldo Lopez, A.; van Dijk, K.; Wang, L.; Brewer, M. T.; Momany, M.; Auxier, B.; Verweij, P. E.
10.1101/2024.07.29.605539 — microbiology — Posted on 2024-07-29
500 The Lag3 and PD-1 pathways govern TCR signal duration and migration of CD4+ T cells
Sheriff, L.; Copland, A.; Lecky, D. A.; Done, R.; George, L. S.; Jennings, E. K.; Rouvray, S.; Elliot, T. A.; Jinks, E. S.; Pallan, L.; Bending, D.
10.1101/2024.06.06.597762 — immunology — Posted on 2024-07-29
501 Optimal placement of high-channel visual prostheses in human retinotopic visual cortex
van Hoof, R.; Lozano, A.; Wang, F.; Klink, P. C.; Roelfsema, P. R.; Goebel, R.
10.1101/2024.03.05.583489 — neuroscience — Posted on 2024-07-29
505 Arc controls organ architecture through modulation of Crb and MyoII
Kim, J. H.; Maruyama, R.; Kim, K.; Vertrees, D.; Paul, P.; Britson, K. A.; Andrew, D. J.
10.1101/2024.07.29.605562 — developmental biology — Posted on 2024-07-29
506 The Small GTPase Rho5 - Yet Another Player in Yeast Glucose Signaling
Schweitzer, F.; Bischof, L.; Walter, S.; Morris, S.; Schmitz, H.-P.; Heinisch, J. J.
10.1101/2024.07.29.605593 — molecular biology — Posted on 2024-07-29
511 Brown Adipose Tissue undergoes pathological perturbations and shapes C2C12 myoblast homeostasis in the SOD1-G93A mouse model of Amyotrophic Lateral Sclerosis.
Rosina, M.; Scaricamazza, S.; Riggio, F.; Fenili, G.; Giannessi, F.; Matteocci, A.; Nesci, V.; Salvatori, I.; Angelini, D. F.; AQUILANO, K.; Chiurchiu, V.; Lettieri Barbato, D.; Mercuri, N. B.; Valle, C.; Ferri, A.
10.1101/2024.07.29.605540 — neuroscience — Posted on 2024-07-29
513 MACanalyzeR: scRNA-seq Analysis Tool Reveals PPARγHI Lipid-Associated Macrophages Facilitate Thermogenic Expansion in BAT
Ninni, A.; Zaccaria, F.; Verteramo, L.; Sciarretta, F.; Silveira, L. S.; Rosa-Neto, J. C.; Grumati, P.; Rizzo, G.; Cochain, C.; Williams, J. W.; Ivanov, S.; Zhou, B.; Aquilano, K.; Lettieri-Barbato, D.
10.1101/2024.07.29.605588 — physiology — Posted on 2024-07-29
515 Structural transitions in kinesin minus-end directed microtubule motility
Shibata, S.; Wang, M. Y.; Imasaki, T.; Shigetmatsu, H.; Wei, Y.; Jobichen, C.; Hagio, H.; Sivaraman, J.; Endow, S. A.; Nitta, R.
10.1101/2024.07.29.605428 — biophysics — Posted on 2024-07-29
516 Detection of Potential Phytochemicals against ctxAB Toxin to Combat Cholera
Akter, Y.; Rahman, K.; Reza, M. S.; Al-Mamun, A.; Alam, M.; Mollah, M. N. H.; MONIR, M. M.
10.1101/2024.07.29.605560 — bioinformatics — Posted on 2024-07-29
518 Mechanistic basis of temperature-adaptation in microtubule dynamics across frog species
Troman, L.; de Gaulejac, E.; Biswas, A.; Stiens, J.; Kuropka, B.; Moores, C.; Reber, S.
10.1101/2024.07.29.605571 — biochemistry — Posted on 2024-07-29
519 Nucleoside diphosphate kinase A (NME1) catalyze its own oligophosphorylation
Celik, A.; Schoepf, F.; Stieger, C. E.; Morgan, J. A. M.; Lampe, S.; Ruwolt, M.; Liu, F.; Hackenberger, C. P. R.; Roderer, D.; Fiedler, D.
10.1101/2024.07.29.605581 — biochemistry — Posted on 2024-07-29
520 Chromosome-level reference genome for the medically important Arabian horned viper (Cerastes gasperettii)
Mochales Riano, G.; Hirst, S. R.; Talavera, A.; Burriel-Carranza, B.; Pagone, V.; Estarellas, M.; Busschau, T.; Boissinot, S.; Hogan, M. P.; Tena-Garces, J.; Pla, D.; Calvete, J. J.; Els, J.; Margres, M. J.; Carranza, S.
10.1101/2024.07.29.605543 — genomics — Posted on 2024-07-29
523 ADAR1 p150 prevents HSV-1 from triggering PKR/eIF2alpha-mediated translational arrest and is required for efficient viral replication
Jurak, I.; Parchure, A. A.; Cesarec, M.; Ivanisevic, V.; Cunko, M.; Bursac, S.; de Reuver, R.; Rosani, U.; Volarevic, S.; Maelfait, J.
10.1101/2024.07.29.605561 — microbiology — Posted on 2024-07-29
524 Resource-efficiency of cyanobacterium production on Mars: Assessment and paths forward
Ramalho, T. P.; Baumgartner, V.; Kunst, N.; Rodrigues, D.; Bohuon, E.; Leroy, B.; Pillot, G.; Heinicke, C.; Kerzenmacher, S.; Avila, M.; Verseux, C.
10.1101/2024.07.29.605555 — microbiology — Posted on 2024-07-29
525 L-Phenylalanine is a metabolic checkpoint of human Th2 cells
Kulkarni, A.; Rodriguez-Coira, J.; Stocker, N.; Radzikowska, U.; Garcia-Civico, A. J.; Delgado-Dolset, M. I.; Contreras, N.; Jardon-Parages, I.; Saiz-Sanchez, V.; Serrano, P.; Izquierdo, E.; Gomez-Casado, C.; Sanchez-Solares, J.; Pablo-Torres, C.; Obeso, D.; Moreno-Aguilar, C.; Luisa Espinazo, M.; Eljaszewicz, A.; Koch, J.; Baerenfaller, K.; Heider, A.; Tan, G.; Escribese, M. M.; Ruiz-Leon, B.; Akdis, C. A.; Arguello, R. J.; Barber, D.; Villasenor, A.; Sokolowska, M.
10.1101/2024.07.29.605231 — immunology — Posted on 2024-07-29
526 The connectional diaschisis and normalization of cortical language network dynamics after basal ganglia and thalamus stroke
Chen, Q.; Guo, X.; Zhong, T.; Yang, J.; Gao, X.; Hu, Z.; Li, J.; Liu, J.; Wang, Y.; Qu, Z.; Li, W.; Li, Z.; Li, W.; Huang, Y.; Chen, J.; Wen, H.; Zhang, Y.; Yuan, B.; Gao, H.
10.1101/2024.07.29.605538 — neuroscience — Posted on 2024-07-29
527 Quantitative assessment and spatial distribution of Plasmopara viticola oospores in vineyard soil
Poeydebat, C.; Courchinoux, E.; Demeaux, I.; Rodriguez, M.; Chataigner, A.; Lelievre, M.; Goutouly, J.-P.; Rossi, J.-P.; Raynal, M.; Deliere, L.; Francois, D.
10.1101/2024.07.29.605284 — plant biology — Posted on 2024-07-29
528 Odor-based real-time detection and identification of pests and diseases attacking crop plants
Arce, C. M.; Mamin, M.; Roder, G.; Kanagendran, A.; Degen, T.; Defossez, E.; Rasmann, S.; AKIYAMA, T.; MINAMI, K.; YOSHIKAWA, G.; Lopez-Hilfiker, F.; Cappellin, L.; Turlings, T.
10.1101/2024.07.29.605549 — plant biology — Posted on 2024-07-29
529 The prion-like protein Doppel: A soluble biomarker steering ovarian cancers peritoneal to circulatory dissemination
Al-Hilal, T.; Azam, M. Z.; Zhang, X.; Wahab, R.; Hasan, M. M.; Kang, B.; Hassan, M. M.; Karim, M.; Choi, J. U.; Rana, M.; Zhang, J.-Y.; Roy, S.; Byun, Y.; Kim, I.-S.; Song, J. Y.; Alam, F.; Toy, E. P.; Reddy, S. Y.
10.1101/2024.07.26.605386 — cancer biology — Posted on 2024-07-29
532 Exploration of Flavonoids to identify Potential Therapeutic Compounds by Targeting the Non-Structural V protein of Nipah Virus
Ahmad, S. R.; Zeyaullah, M.; AlShahrani, A. M.; Khan, M. S.; Ali, H.; Muzammil, K.; Mohieldin, A.; AG Altijani, A.; Dawria, A.; Mohamed, A. O. A.; Kalam, A.
10.1101/2024.07.29.605559 — biochemistry — Posted on 2024-07-29
534 MitoNEET reduces the mitochondrial oxidative phosphorylation during epithelial-mesenchymal transition
Handa, H.; Onodera, Y.; Oikawa, T.; Takada, S.; Ueda, K.; Setoyama, D.; Yokota, T.; Yamasaki, M.; Watanabe, M.; Fumoto, Y.; Hashimoto, A.; Hata, S.; Murakami, M.; Sabe, H.
10.1101/2024.07.29.603210 — cell biology — Posted on 2024-07-29
535 Nomination of a novel plasma protein biomarker panel capable of classifying Alzheimer's disease dementia with high accuracy in an African American cohort
Kuchenbecker, L. A.; Thompson, K. J.; Hurst, C. D.; Opdenbosch, B. M.; Heckman, M. G.; Reddy, J. S.; Nguyen, T.; Casellas, H. L.; Reddy, D. J.; Lucas, J. A.; Day, G. S.; Willis, F. B.; Graff-Radford, N. R.; Ertekin-Taner, N.; Kalari, K. R.; Carrasquillo, M. M.
10.1101/2024.07.27.605373 — neuroscience — Posted on 2024-07-29
547 Caught in the act of triplication: TNF superfamily
Menon, N.; K, K.; Goswami, M.; Singh, A.; Srinivasan, S.
10.1101/2024.07.27.603686 — bioinformatics — Posted on 2024-07-29
548 CardioMEA: Comprehensive Data Analysis Platform for Studying Cardiac Diseases and Drug Responses
Lee, J.; Duperrex, E.; El-Battrawy, I.; Hohn, A.; Saguner, A. M.; Duru, F.; Emmenegger, V.; Cyganek, L.; Hierlemann, A.; Ulusan, H.
10.1101/2024.07.28.605490 — bioengineering — Posted on 2024-07-29
551 Introgression dynamics of sex-linked chromosomal inversions shape the Malawi cichlid adaptive radiation
Blumer, L. M.; Burskaia, V.; Artiushin, I.; Saha, J.; Camacho Garcia, J.; Elkin, J.; Fischer, B.; Zhou, C.; Gresham, S.; Malinsky, M.; Linderoth, T.; Sawasawa, W.; Bista, I.; Hickey, A.; Kucka, M.; Louzada, S.; Zatha, R.; Yang, F.; Rusuwa, B.; Santos, M. E.; Chan, Y. F.; Joyce, D. A.; Böhne, A.; Miska, E. A.; Ngochera, M.; Turner, G. F.; Durbin, R.; Svardal, H.
10.1101/2024.07.28.605452 — evolutionary biology — Posted on 2024-07-29
557 Coordinated regulation of chemotaxis and resistance to copper by CsoR in Pseudomonas putida
He, M.; Tao, Y.; Mu, K.; Feng, H.; Fan, Y.; Liu, T.; Huang, Q.; Xiao, Y.; Chen, W.
10.1101/2024.07.28.605504 — microbiology — Posted on 2024-07-29
558 Aging trajectories of memory CD8+ T cells differ by their antigen specificity
Sturmlechner, I.; Jain, A.; Hu, B.; Jadhav, R.; Cao, W.; Okuyama, H.; Tian, L.; Weyand, C.; Goronzy, J.
10.1101/2024.07.26.605197 — immunology — Posted on 2024-07-29
564 Differential Patterns of Gut and Oral Microbiomes in Hispanic Individuals with Cognitive Impairment
Wadop Ngouongo, Y.; Vasquez, E. L.; Mathews, J. J.; Muhammad, J. A. S.; Mavarez, R. P.; Satizabal, C.; Gonzales, M. M.; Tanner, J.; Maestre, G.; Fonteh, A. N.; Seshadri, S.; Kautz, T. F.; Fongang, B.
10.1101/2024.07.27.605455 — neuroscience — Posted on 2024-07-29
565 Maintenance of taste receptor cell presynaptic sites requires gustatory nerve fibers
Landon, S. M.; Holder, E.; Ng, A.; Wood, R. M.; Gutierrez Kuri, E.; Pinto, L.; Humayun, S.; Macpherson, L. J.
10.1101/2024.07.28.604832 — neuroscience — Posted on 2024-07-29
567 AraRoot - A Comprehensive Genome-Scale Metabolic Model for the Arabidopsis Root System.
Esterhuizen, L.; Ampimah, N.; Yandeau-Nelson, M.; Nikolau, B. J.; Sparks, E. E.; Saha, R.
10.1101/2024.07.28.605515 — systems biology — Posted on 2024-07-29
569 The nuclear-cytoplasmic ratio controls the cell cycle period in compartmentalized frog egg extract
Pineros, L.; Frolov, N.; Ruiz-Reynes, D.; Van Eynde, A.; Cavin-Meza, G. J.; Heald, R.; Gelens, L.
10.1101/2024.07.28.605512 — biophysics — Posted on 2024-07-29
571 Protein surface chemistry encodes an adaptive resistance to desiccation
Romero-Perez, P. S.; Moran, H. M.; Horani, A.; Truong, A.; Manriquez-Sandoval, E.; Ramirez, J. F.; Martinez, A.; Golub, E.; Hunter, K.; Lotthammer, J. M.; Emenecker, R. J.; Boothby, T. C.; Holehouse, A. S.; Fried, S. D.; Sukenik, S.
10.1101/2024.07.28.604841 — biophysics — Posted on 2024-07-29
574 PerturbAtlas: A Comprehensive Atlas of Public Genetic Perturbation Bulk RNA-seq Datasets
Zhang, Y.; Zhang, T.; Yang, G.; Pan, Z.; Tang, M.; He, P.; Wen, Y.; Wang, Y.; Zhou, R.
10.1101/2024.07.28.605482 — bioinformatics — Posted on 2024-07-29
577 Genetic diversity and evolution of rice centromeres
Xie, L.; Huang, Y.; Huang, W.; Shang, l.; Sun, Y.; Chen, Q.; Bi, S.; Suo, M.; Zhang, S.; Yang, C.; Zheng, X.; Jin, W.; Qian, Q.; Fan, L.; Dongya, W.
10.1101/2024.07.28.605524 — genetics — Posted on 2024-07-29
578 A path analysis disentangling determinants of natal dispersal in a cooperatively breeding bird
Borger, M. J.; Lee, K. G. L.; Weissing, F. J.; Richardson, D. S.; Dugdale, H. L.; Burke, T.; Pen, I.; Komdeur, J.
10.1101/2024.07.26.605387 — ecology — Posted on 2024-07-29
582 IPMK Deficiency Reduces Skeletal Muscle Oxidative Metabolism and Exercise Capacity
Lee, J.-H.; Jung, I.-R.; Tu-Sekine, B.; Jin, S.; Anokye-Danso, F.; Ahima, R. S.; Kim, S. F.
10.1101/2024.07.28.605526 — molecular biology — Posted on 2024-07-29
583 A retrograde transit filter mediated by optineurin controls mitostasis in distal axons
Marahori, N. A.; Gailer, B.; Schifferer, M.; Kleele, T.; Iatroudi, A.; Hannan, S. B.; Avramopoulos, P.; Engelhardt, S.; Lakadamyali, M.; Brill, M. S.; Misgeld, T.
10.1101/2024.07.28.604753 — cell biology — Posted on 2024-07-29
584 Mapping the nuclear landscape with multiplexed super-resolution fluorescence microscopy
Rahman, F.; Augoustides, V.; Tyler, E.; Daugird, T. A.; Arthur, C.; Legant, W. R.
10.1101/2024.07.27.605159 — cell biology — Posted on 2024-07-29
587 Fundamental limitations of kilohertz-frequency carriers in afferent fiber recruitment with transcutaneous spinal cord stimulation
Keesey, R.; Hofstoetter, U.; Hu, Z.; Lombardi, L.; Hawthorn, R.; Bryson, N. K.; Rowald, A.; Minassian, K.; Seanez, I.
10.1101/2024.07.26.603982 — neuroscience — Posted on 2024-07-29
591 Synaptogyrin-3 Prevents Cocaine Addiction and Dopamine Deficits
Peck, E. G.; Holleran, K. M.; Curry, A. M.; Holter, K. M.; Estave, P.; Sens, J. P.; Locke, J.; Ortelli, O.; George, B.; Dawes, M.; West, A. M.; Alexander, N.; Kiraly, D.; Farris, S.; Gould, R. W.; McCool, B.; Jones, S. R.
10.1101/2024.07.27.605436 — neuroscience — Posted on 2024-07-29
592 Dopamine reveals adaptive learning of actions representation
Come, M.; Gulmez, A.; Keshishian, L.; Jehl, J.; Bousseyrol, E.; Didienne, S.; Vicq, E.; Le Borgne, T.; Mourot, A.; Faure, P.
10.1101/2024.07.28.605479 — neuroscience — Posted on 2024-07-29
594 Imaging of developing human brains with ex vivo PSOCT and dMRI
Wang, H.; Blanke, N.; Gong, D.; Ortug, A.; Alatorre Warren, J. L.; Clickner, C.; Ammon, W.; Nolan, J.; Cotronis, Z.; van der Kouwe, A.; Takahashi, E.
10.1101/2024.07.27.605383 — neuroscience — Posted on 2024-07-29
595 Single field evolution rule governs the dynamics of representational drift in mouse hippocampal dorsal CA1 region.
Chen, C.; Yao, S.; Cheng, S.; Li, A. A.; Yan, Y.; Zhang, X.; Liu, Y.; Wang, Y.; Cao, Q.; Miao, C.
10.1101/2024.07.27.605419 — neuroscience — Posted on 2024-07-29
597 A common pathway controls cell size in the sepal and leaf epidermis leading to a non-random pattern of giant cells
Clark, F. K.; Weissbart, G.; Wang, X.; Harline, K.; Li, C.-B.; Formosa-Jordan, P.; Roeder, A. H. K.
10.1101/2024.07.26.605215 — plant biology — Posted on 2024-07-29
598 Rapid oxygen titration following cardiopulmonary resuscitation mitigates cerebral overperfusion and striatal mitochondrial dysfunction in asphyxiated newborn lambs
Badurdeen, S.; Galinsky, R.; Roberts, C.; Crossley, K. J.; Zahra, V.; Thiel, A.; Pham, Y.; Davis, P.; Hooper, S. B.; Polglase, G.; Camm, E.
10.1101/2024.07.27.603805 — physiology — Posted on 2024-07-29
600 Overcrowding Drives Tumor Invasion by Inducing Nanotopographical Transition of Plasma Membrane
Zhao, X.; Tan, M.; Li, L.; Lin, X.; Li, Z.; Wang, X.; Song, B.; Guo, Z.; Chen, T.; Hou, S.; Fan, J.; Wang, S.; Zhang, Y.; Fan, Y.; Du, J.
10.1101/2024.07.28.605413 — cancer biology — Posted on 2024-07-29
601 Accurate, fast and memory efficient quantification of immune cell phenotypes in cytometry using machine learning
Exner, T.; Hackert, N. S.; Pohl, F.; Osmanusta, G.; Schmidt, F.; Lorenz, H.-M.; Wabnitz, G.; Schett, G.; Graw, F.; Henes, J.; Grieshaber-Bouyer, R.
10.1101/2024.07.26.605341 — bioinformatics — Posted on 2024-07-29
607 Comparing efficiencies of population control methods for responding to foreign animal disease threats in wild pigs
Snow, N. P.; Smith, B.; Lavelle, M.; Glow, M.; Chalkowski, K.; Leland, B.; Sherburne, S.; Fischer, J.; Kohen, K.; Cook, S.; Smith, H.; VerCauteren, K. C.; Miller, R.; Pepin, K.
10.1101/2024.07.26.605354 — ecology — Posted on 2024-07-29
609 Limitations in mitochondrial programming restrain the differentiation and maturation of human stem cell-derived β cells
Lietzke, A. C.; Bealer, E.; Crumley, K.; King, J.; Stendahl, A. M.; Zhu, J.; Pearson, G. L.; Levi-DAncona, E.; Henry-Kanarek, B.; Reck, E. C.; Arnipalli, M.; Sidarala, V.; Walker, E. M.; Pennathur, S.; Madsen, J. G. S.; Shea, L. D.; Soleimanpour, S. A.
10.1101/2024.07.26.605318 — developmental biology — Posted on 2024-07-29
610 Single cell autofluorescence imaging reveals immediate metabolic shifts of neutrophils with activation across biological systems
Datta, R.; Miskolci, V.; Gallego Lopez, G. M.; Britt, E.; Gillette, A.; Kralovec, A.; Giese, M. A.; Qian, T.; Fan, J.; Huttenlocher, A.; Skala, M. C.
10.1101/2024.07.26.605362 — immunology — Posted on 2024-07-29
613 GRAViTy-V2: a grounded viral taxonomy application
Mayne, R. M.; Aiewsakun, P.; Turner, D.; Adriaenssens, E. M.; Simmonds, P.
10.1101/2024.07.26.605250 — bioinformatics — Posted on 2024-07-29
614 Structure of scavenger receptor SCARF1 and its interaction with lipoproteins
Wang, Y.; Xu, F.; Li, G.; Cheng, C.; Yu, B.; Zhang, Z.; Kong, D.; Chen, F.; Liu, Y.; Fang, Z.; Cao, L.; Yu, Y.; Gu, Y.; He, Y.
10.1101/2023.11.08.566208 — biophysics — Posted on 2024-07-29
615 Desmodium Volatiles in "Push-Pull" Agriculture and Protection Against the Fall Armyworm, Spodoptera frugiperda
Odermatt, D. M.; Chidawanyika, F.; Mutyambai, D. M.; Schmid, B.; Domeignoz Horta, L. A.; Tamiru, A.; Schuman, M. C.
10.1101/2024.07.24.604900 — ecology — Posted on 2024-07-29
619 Characterisation and comparison of semen microbiota and sperm function in men with infertility, recurrent miscarriage, or proven fertility
Mowla, S.; Farahani, L.; Tharakan, T.; Davies, R.; Correia, G. D.; Lee, Y. S.; Kundu, S.; Khanjani, S.; Sindi, E.; Rai, R.; Regan, L.; Khalifa, D.; Henkel, R.; Minhas, S.; S. Dhillo, W.; Ben Nagi, J.; Bennett, P.; MacIntrye, D. A.; Jayasena, C. N.
10.1101/2024.02.18.580923 — microbiology — Posted on 2024-07-29
620 Assemblies, synapse clustering and network topology interact with plasticity to explain structure-function relationships of the cortical connectome
Ecker, A.; Egas Santander, D.; Abdellah, M.; Blanco Alonso, J.; Bolanos-Puchet, S.; Chindemi, G.; Gowri Mariyappan, D. P.; Isbister, J. B.; King, J. G.; Kumbhar, P.; Magkanaris, I.; Muller, E. B.; Reimann, M. W.
10.1101/2023.08.07.552264 — neuroscience — Posted on 2024-07-29
623 Bifunctional probes reveal the rules of intracellular ether lipid transport
Böhlig, K.; Iglesias-Artola, J. M.; Lennartz, H. M.; Link, A. C.; Drobot, B.; Nadler, A.
10.1101/2024.07.26.605283 — cell biology — Posted on 2024-07-29
630 Intramolecular feedback regulation of the LRRK2 Roc G domain by a LRRK2 kinase dependent mechanism
Gilsbach, B. K.; Ho, F. Y.; Riebenbauer, B.; Zhang, X.; Guaitoli, G.; Kortholt, A.; Gloeckner, C. J.
10.1101/2023.07.31.549909 — biochemistry — Posted on 2024-07-29
634 Using normative models pre-trained on cross-sectional data to evaluate longitudinal changes in neuroimaging data
Rehak Buckova, B.; Fraza, C.; Rehak, R.; Kolenic, M.; Beckmann, C.; Spaniel, F.; Marquand, A.; Hlinka, J.
10.1101/2023.06.09.544217 — neuroscience — Posted on 2024-07-29
635 Human V4 size predicts crowding distance
Kurzawski, J. W.; Qiu, B. S.; Majaj, N. J.; Benson, N. C.; Pelli, D.; Winawer, J.
10.1101/2024.04.03.587977 — neuroscience — Posted on 2024-07-29
636 AgRP1 modulates breeding season-dependent feeding behavior in female medaka
Tagui, Y.; Takeda, S.; Waida, H.; Kitahara, S.; Kimura, T.; Kanda, S.; Oka, Y.; Hayashi, Y.; Umatani, C.
10.1101/2024.07.10.602830 — neuroscience — Posted on 2024-07-29
637 The spatial layout of antagonistic brain regions is explicable based on geometric principles
Leech, R.; Braga, R.; Haydock, D.; Vowles, N.; Jefferies, E.; Bernhardt, B.; Turkheimer, F. E.; Alberti, F.; Margulies, D.; Sherwood, O.; Jones, E. J.; Smallwood, J.; Vasa, F.
10.1101/2024.06.17.599309 — neuroscience — Posted on 2024-07-29
638 Isoform-specific C-terminal phosphorylation drives autoinhibition of Casein Kinase 1
Harold, R. L.; Tulsian, N. K.; Narasimamurthy, R.; Yaitanes, N.; Hernandez, M. G. A.; Lee, H.-W.; Crosby, P.; Tripathi, S.; Virshup, D. M.; Partch, C. L.
10.1101/2023.04.24.538174 — biochemistry — Posted on 2024-07-29
640 Spatial dynamics of mammalian brain development and neuroinflammation by multimodal tri-omics mapping
Zhang, D.; Rubio Rodriguez-Kirby, L. A.; Lin, Y.; Song, M.; Wang, L.; Wang, L.; Kanatani, S.; Jimenez-Beristain, T.; Dang, Y.; Zhong, M.; Kukanja, P.; Wang, S.; Chen, X. L.; Gao, F.; Wang, D.; Hang, X.; Lou, X.; Liu, Y.; Chen, J.; Sestan, N.; Uhlen, P.; Kriegstein, A.; Zhao, H.; Castelo-Branco, G.; Fan, R.
10.1101/2024.07.28.605493 — neuroscience — Posted on 2024-07-28
641 Characterization of Eye and Adnexal Tissues in Dogs and Wolves: A Histological and Lectin-Histochemical Approach
Diz Lopez, A.; Torres, M. V.; Martinez Gomez, F.; Lopez Beceiro, A. M.; Fidalgo, L.; Sanchez-Quinteiro, P.; Ortiz Leal, I.
10.1101/2024.07.26.605385 — neuroscience — Posted on 2024-07-28
642 The genetic architecture of resistance to flubendiamide insecticides in Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae)
Amado, D.; Koch, E. L.; Cordeiro, E. M. G.; Araujo, W. A.; Garcia, A. A. F.; Heckel, D. G.; Montejo-Kovacevich, G.; North, H. L.; Correa, A. S.; Jiggins, C. D.; Omoto, C.
10.1101/2024.07.28.605483 — genetics — Posted on 2024-07-28
643 pH dependent direct sulfhydrylation pathway is required for pathogenesis of Mycobacterium tuberculosis
Nain, V. K.; Barik, V.; Pandey, M.; Pareek, M.; Sharma, T.; Pal, R.; Tyagi, S.; Bajpai, M.; Dwivedi, P.; Panda, B. N.; Kumar, Y.; Asthana, S.; Pandey, A. K.
10.1101/2024.07.28.605477 — microbiology — Posted on 2024-07-28
645 Reassessment of body temperature and thermoregulation strategies in Mesozoic marine reptiles
Seon, N.; Vincent, P.; Delsett, L. L.; Poulallion, E.; Suan, G.; Lecuyer, C.; Roberts, A. J.; Fourel, F.; Charbonnier, S.; Amiot, R.
10.1101/2024.07.26.605303 — paleontology — Posted on 2024-07-28
646 Compaction-mediated segregation of partly replicated bacterial chromosome
Brahmachari, S.; Oliveira, A. B.; Mello, M. F.; Contessoto, V. G.; Onuchic, J. N.
10.1101/2024.07.27.604869 — biophysics — Posted on 2024-07-28
648 Multi-Modal CLIP-Informed Protein Editing
Yin, M.; Zhou, H.; Zhu, Y.; Lin, M.; Wu, Y.; Wu, J.; Xu, H.; Hsieh, C.-Y.; Hou, T.; Chen, J.; Wu, J.
10.1101/2024.07.28.605469 — bioinformatics — Posted on 2024-07-28
649 Active Learning-Assisted Directed Evolution
Yang, J.; Lal, R. G.; Bowden, J. C.; Astudillo, R.; Hameedi, M. A.; Kaur, S.; Hill, M.; Yue, Y.; Arnold, F. H.
10.1101/2024.07.27.605457 — bioengineering — Posted on 2024-07-28
650 Investigation of Intestinal Bacteria-binding Monoclonal Antibodies Derived from Rabbit Single B Cells
Anwar, K.; Kaneko, S.; Kawakita, I.; Adinegoro, D. S.; Kihara, M.; Ojima-Kato, T.; Nakano, H.
10.1101/2024.07.26.605397 — bioengineering — Posted on 2024-07-28
652 Mapping the peripheral immune landscape of Parkinson's disease patients with single-cell sequencing
Moquin-Beaudry, G.; Andriamboavonjy, L.; Audet, S.; Hamilton, L.; Duquette, A.; Chouinard, S.; Panisset, M.; Tetreault, M.
10.1101/2024.07.26.605020 — genetics — Posted on 2024-07-28
653 Environmental versus litter traits as drivers of microbial decomposer functions
Stock, S. C.; Canessa, R.; van den Brink, L.; Cavieres, L. A.; Kappler, A.; Merino Guzman, C.; Saldana, A.; Scholten, T.; Schweiger, A. H.; Rehfeld, K.; Neidhardt, H.; Oelmann, Y.; Tielboerger, K.; Bader, M. Y.; Ehlers, T. A.; Dippold, M. A.
10.1101/2024.07.26.605152 — ecology — Posted on 2024-07-28
655 12-Lipoxygenase Inhibition Suppresses Islet Immune and Inflammatory Responses and Delays Autoimmune Diabetes in Human Gene Replacement Mice
Nargis, T.; Muralidharan, C.; Enriquez, J. R.; Wang, J. E.; Kaylan, K.; Chakraborty, A.; Pratuagntham, S.; Figatner, K.; Nelson, J. B.; May, S. C.; Nadler, J. L.; Boxer, M. B.; Maloney, D. J.; Tersey, S. A.; Mirmira, R. G.
10.1101/2024.07.28.604986 — molecular biology — Posted on 2024-07-28
656 TNF Superfamily Member 14 Drives Post-Influenza Depletion of Alveolar Macrophages Enabling Secondary Pneumococcal Pneumonia
Malainou, C.; Peteranderl, C.; Ferrero, M. R.; Vazquez-Armendariz, A. I.; Alexopoulos, I.; Better, J.; Estiri, M.; Schultheis, H.; Hoppe, J.; del Rio, M.-L.; Rodriguez-Barbosa, J. I.; Pfeffer, K.; Gunther, S.; Looso, M.; Gruber, A. D.; Vadasz, I.; Matt, U.; Herold, S.
10.1101/2024.07.28.605445 — molecular biology — Posted on 2024-07-28
658 Exploring the Single-Cell Dynamics of FOXM1 Under Cell Cycle Perturbations
Jawwad, T.; Kamkaew, M.; Phongkitkarun, K.; Chusorn, P.; Sampattavanich, S.
10.1101/2024.07.27.605093 — systems biology — Posted on 2024-07-28
659 Discovery and Quantification of Long-Range RNA Base Pairs in Coronavirus Genomes with SEARCH-MaP and SEISMIC-RNA
Allan, M. F.; Aruda, J.; Plung, J. S.; Grote, S. L.; Martin, Y. J.; de Lajarte, A. A.; Bathe, M.; Rouskin, S.
10.1101/2024.04.29.591762 — molecular biology — Posted on 2024-07-28
661 The transcriptional response and genomic signature of metal tolerance in brown trout inhabiting metal-polluted rivers
Paris, J. R.; King, R. A.; Ferrer Obiol, J.; Shaw, S.; Lange, A.; Bourret, V.; Hamilton, P. B.; Rowe, D.; Laing, L. V.; Farbos, A.; Moore, K. A.; Urbina, M. A.; Catchen, J. M.; Wilson, R. W.; Bury, N. R.; Santos, E. M.; Stevens, J. R.
10.1101/2024.05.30.595956 — evolutionary biology — Posted on 2024-07-28
663 Pretrainable Geometric Graph Neural Network for Antibody Affinity Maturation
Cai, H.; Zhang, Z.; Wang, M.; Zhong, B.; Li, Q.; Zhong, Y.; Wu, Y.; Ying, T.; Tang, J.
10.1101/2023.08.10.552845 — bioinformatics — Posted on 2024-07-28
665 Transfer RNA acetylation regulates in vivo mammalian stress signaling
Thalalla Gamage, S.; Khoogar, R.; Howpay Manage, S. A.; Crawford, M. C.; Georgeson, J.; Polevoda, B. V.; Sanders, C.; Lee, K. A.; Nance, K. D.; Iyer, V.; Kustanovich, A.; Perez, M.; Thu, C. T.; Nance, S. R.; Amin, R.; Miller, C. N.; Holewinski, R. J.; Meyer, T.; Koparde, V.; Yang, A.; Jailwala, P.; Nguyen, J. T.; Andresson, T.; Hunter, K.; Gu, S.; Mock, B. A.; Edmondson, E. F.; Difilippantonio, S.; Chari, R.; Schwartz, S.; O'Connell, M. R.; Wu, C. C.-C.; Meier, J. L.
10.1101/2024.07.25.605208 — cell biology — Posted on 2024-07-28
668 AutoMorFi: Automated Whole-image Morphometry in Fiji/ImageJ for Diverse Image Analysis Needs
Bouadi, O.; Yao, C.; Zeng, J.; Beason, D.; Inda, N.; Malone, Z.; Yoshihara, J.; Manjally, A. V.; Johnson, C.; Cherry, J.; Chen, C.-Y.; Huang, T.-C.; Popovic, B.; Henley, M.; Liu, G.; Kharitonova, E.; Zeldich, E.; Aichelman, H.; Davies, S. W.; Walentek, P.; Tian, Y.; Man, H.; Ozsen, E.; Harder, K.; Gilmore, T. D.; Pitt, D.; Tay, T. L.
10.1101/2024.07.26.605357 — cell biology — Posted on 2024-07-27
669 A novel quinone biosynthetic pathway illuminates the evolution of aerobic metabolism
Elling, F. J.; Pierrel, F.; Chobert, S.-C.; Abby, S. S.; Evans, T. W.; Reveillard, A.; Pelosi, L.; Schnoebelen, J.; Hemingway, J. D.; Boumendjel, A.; Becker, K. W.; Blom, P.; Cordes, J.; Nathan, V.; Baymann, F.; Lucker, S.; Spieck, E.; Leadbetter, J. R.; Hinrichs, K.-U.; Summons, R. E.; Pearson, A.
10.1101/2024.07.27.605408 — microbiology — Posted on 2024-07-27
670 Cell-free expression of Nipah virus transmembrane proteins for proteoliposome vaccine design
Hu, V. T.; Ezzatpour, S.; Selivanovitch, E. T.; Carter, J.; Sahler, J.; Adeleke, R. A.; August, A.; Aguilar-Carreno, H.; Daniel, S.; Kamat, N. P.
10.1101/2024.07.26.605347 — synthetic biology — Posted on 2024-07-27
674 Imputing Single-Cell Protein Abundance in Multiplex Tissue Imaging
Kirchgaessner, R.; Watson, C.; Creason, A. L.; Keutler, K.; Goecks, J.
10.1101/2023.12.05.570058 — cancer biology — Posted on 2024-07-27
675 Mechano-metabolism of metastatic breast cancer cells in 2D and 3D microenvironments
Jaganathan, A.; Toth, J. M.; Chen, X.; Basir, R.; Pieuchot, L.; Shen, Y.; Reinhart-King, C. A.; Shenoy, V. B.
10.1101/2024.04.30.591879 — biophysics — Posted on 2024-07-27
677 A fluorescent biosensor for the visualization of agmatine
Kröger, P.; Stiel, A. C.; Stüven, B.; Shanmugaratnam, S.; Schoch, S.; Wachten, D.; Höcker, B.
10.1101/2024.07.27.605435 — biochemistry — Posted on 2024-07-27
681 Comparative Genomic Analysis of Campylobacter rectus and Closely Related Species
Hughes Lago, C. A.; Blackburn, D.; Kinder Pavlicek, M.; Threadgill, D. S.
10.1101/2024.07.26.605372 — genomics — Posted on 2024-07-27
684 Vestigial like 4 regulates the adipogenesis of classical brown adipose tissue
Zhou, P.; Kessinger, C. W.; Gu, F.; King, J. S.; Davenport, A.; Wang, G.; Negron, S. G.; Deplancke, B.; Pu, W. T.; Lin, Z.
10.1101/2024.07.09.602788 — developmental biology — Posted on 2024-07-27
685 Characterisation of human hair follicle development
Sudderick, Z. R.; Glover, J. D.; Batho-Samblas, C.; Shih, B. B.-J.; Headon, D. J.
10.1101/2024.07.26.605346 — developmental biology — Posted on 2024-07-27
686 Transfer RNA acetylation regulates in vivo mammalian stress signaling
Thalalla Gamage, S.; Khoogar, R.; Howpay Manage, S. A.; Crawford, M. C.; Georgeson, J.; Polevoda, B. V.; Sanders, C.; Lee, K. A.; Nance, K. D.; Iyer, V.; Kustanovich, A.; Perez, M.; Thu, C. T.; Nance, S. R.; Miller, C. N.; Holewinski, R. J.; Meyer, T.; Koparde, V.; Yang, A.; Jailwala, P.; Nguyen, J. T.; Andresson, T.; Mock, B. A.; Gu, S.; Edmondson, E. F.; Difilippantonio, S.; Chari, R.; Schwartz, S.; O'Connell, M. R.; Wu, C. C.-C.; Meier, J. L.
10.1101/2024.07.25.605208 — cell biology — Posted on 2024-07-27
687 Development of antisense tools to study Bodo saltans and its intracellular symbiont
Ahrar, M.; Glenn, L.; Held, M.; Jackson, A.; Kus, K.; Hurst, G. D.; Chrostek, E.
10.1101/2024.07.27.605423 — molecular biology — Posted on 2024-07-27
690 Polyamines sustain epithelial regeneration in aged intestines by modulating protein homeostasis
Minetti, A.; Omrani, O.; Brenner, C.; Allies, G.; Imada, S.; Roesler, J.; Khawaled, S.; Cansiz, F.; Meckelmann, S.; Gebert, N.; Heinze, I.; Lu, J.; Spengler, K.; Rasa, M.; Heller, R.; Yilmaz, O. H.; Tasdogan, A.; Neri, F.; Ori, A.
10.1101/2024.07.26.605278 — molecular biology — Posted on 2024-07-27
692 Urea assimilation and oxidation supports the activity of a phylogenetically diverse microbial community in the dark ocean
Arandia-Gorostidi, N.; Jaffe, A. L.; Parada, A. E.; Kapili, B. J.; Casciotti, K. L.; Salcedo, R. S. R.; Baumas, C. M. J.; Dekas, A. E.
10.1101/2024.07.26.605319 — microbiology — Posted on 2024-07-27
694 Investigation of the threonine metabolism of Echinococcus multilocularis: the threonine dehydrogenase as a potential drug target in alveolar echinococcosis
Kaethner, M.; Zumstein, P.; Preza, M.; Bartetzko, A.; Grossenbacher, P.; Lochner, M.; Schuerch, S.; Regnault, C.; Ramirez, D. V.; Lundstroem-Stadelmann, B.
10.1101/2024.07.27.605433 — microbiology — Posted on 2024-07-27
695 Gut microbiota metabolically mediate intestinal helminth infection in Zebrafish
Hammer, A. J.; Gaulke, C. A.; Garcia - Jaramillo, M.; Leong, C.; Morre, J. T.; Sieler, M. J.; Stevens, J. F.; Jiang, Y.; Maier, C. S.; Kent, M. L.; Sharpton, T. J.
10.1101/2024.07.26.605207 — microbiology — Posted on 2024-07-27
696 Chemically-informed coarse-graining of electrostatic forces in charge-richbiomolecular condensates
Tejedor, A. R.; Aguirre Gonzalez, A.; Maristany, M. J.; Chew, P. Y.; Rusell, K.; Ramirez, J.; Espinosa, J. R.; Collepardo-Guevara, R.
10.1101/2024.07.26.605370 — biophysics — Posted on 2024-07-27
697 Nucleotide dependency analysis of DNA language models reveals genomic functional elements
Tomaz da Silva, P.; Karollus, A.; Hingerl, J.; Galindez, G.; Wagner, N.; Hernandez-Alias, X.; Incarnato, D.; Gagneur, J.
10.1101/2024.07.27.605418 — genomics — Posted on 2024-07-27
705 The intersection of endocrine signaling and neuroimmune communication regulates neonatal nociception
Fadaka, A. O.; Dourson, A. J.; Hofmann, M. C.; Gupta, P.; Raut, N. G. R.; Jankowski, M. P.
10.1101/2024.07.26.605393 — neuroscience — Posted on 2024-07-27
706 SGLT2 inhibitors activate pantothenate kinase in the human heart
Forelli, N.; Eaton, D.; Patel, J.; Bowman, C.; Kawakami, R.; Kuzetsnov, I.; Li, K.; Brady, C.; Bedi, K.; Yang, Y.; Koya, K.; Megill, E.; Kantner, D.; Smith, L.; Bowman, G.; Snyder, N.; Edwards, J.; Margulies, K.; Arany, Z.
10.1101/2024.07.26.605401 — biochemistry — Posted on 2024-07-27
707 Proteomic Profiling Reveals Age-Related Changes in Transporter Proteins in the Human Blood-Brain Barrier
Zhou, X.; Azimi, M.; Handin, N.; Riselli, A.; Vora, B.; Chun, E.; Yee, S. W.; Artursson, P.; Giacomini, K. M.
10.1101/2024.07.26.604313 — developmental biology — Posted on 2024-07-27
715 Assembly of mTORC3 involves binding of ETV7 to two separate sequences in the mTOR kinase domain.
Zhan, J.; Harwood, F. C.; Have, S. T.; Lamond, A. I.; Halder, P.; Kriwacki, R.; Grosveld, G. C.; Phillips, A.; Cardone, M.
10.1101/2024.03.19.583970 — cancer biology — Posted on 2024-07-27
716 ChemPrint: An AI-Driven Framework for Enhanced Drug Discovery
Umansky, T.; Woods, V.; Russell, S. M.; Smith, D. M.; Haders, D.
10.1101/2024.03.22.586314 — bioinformatics — Posted on 2024-07-27
718 The genetic basis of the black pupae phenotype in tephritid fruit flies
Paulo, D. F.; Nguyen, T. N. M.; Ward, C. M.; Corpuz, R. L.; Kauwe, A. N.; Rendon, P.; Ruano, R. E. Y.; Cardoso, A. A. S.; Gouvi, G.; Fung, E.; Crisp, P.; Okada, A.; Choo, A.; Stauffer, C.; Bourtzis, K.; Sim, S. B.; Baxter, S. W.; Geib, S. M.
10.1101/2024.06.07.597636 — genomics — Posted on 2024-07-27
720 Growth parameters of the clupeids Limnothrissa miodon and Stolothrissa tanganicae in northern Lake Tanganyika (Bujumbura sub-basin)
N'Sibula, M. T.; Gordo-Vilaseca, C.; Milec, L. J. M.; Patel, D. M.; Kankonda, A. B.; Micha, J.-C.; Sarvala, J.; Raeymaekers, J. A. M.
10.1101/2024.03.16.584994 — ecology — Posted on 2024-07-27
722 Long-range chemical signalling in vivo is regulated by mechanical signals
Pillai, E. K.; Mukherjee, S.; Gampl, N.; McGinn, R. J.; Mooslehner, K. A.; Becker, J.; Thompson, A. J.; Franze, K.
10.1101/2024.02.15.580459 — developmental biology — Posted on 2024-07-27
723 Modelling genetic risk of β-cell dysfunction in human induced pluripotent stem cells from patients carrying the MTNR1B risk variant.
Singh, T.; Kalamajski, S.; Cunha, J. P. M. C. M.; Hladkou, S.; Roberts, F.; Gheibi, S.; Soltanian, A.; Yektay Farahmand, K.; Ekstrom, O.; Mamidi, A.; Franks, P. W.; Rosengren, A.; Semb, H.; Mulder, H.; Fex, M.
10.1101/2024.07.19.603674 — cell biology — Posted on 2024-07-27
724 Interpretable representation learning for 3D multi-piece intracellular structures using point clouds
Vasan, R.; Ferrante, A.; Borensztejn, A.; Frick, C. L.; Gaudreault, N.; Mogre, S. S.; Morris, B.; Pires, G. G.; Rafelski, S. M.; Theriot, J. A.; Viana, M. P.
10.1101/2024.07.25.605164 — cell biology — Posted on 2024-07-27
730 Imputing Single-Cell Protein Abundance in Multiplex Tissue Imaging
Kirchgaessner, R.; Watson, C.; Creason, A. L.; Keutler, K.; Goecks, J.
10.1101/2023.12.05.570058 — cancer biology — Posted on 2024-07-27
731 Single-molecule analysis reveals TDG exhibits multiple modes of linear diffusion to process 5-formylcytosine.
Schnable, B. L.; Schaich, M. A.; Roginskaya, V.; Leary, L. P.; Weaver, T. M.; Freudenthal, B. D.; Drohat, A. C.; Van Houten, B.
10.1101/2023.10.04.560925 — biophysics — Posted on 2024-07-27
733 Identification of SLC25A46 interaction interfaces with mitochondrial membrane fusogens Opa1 and Mfn2
Boopathy, S.; Luce, B. E.; Lugo, C. M.; Hakim, P.; McDonald, J. L.; Kim, H. L.; Ponce, J.; Ueberheide, B.; Chao, L. H.
10.1101/2023.12.29.573615 — biochemistry — Posted on 2024-07-27
738 A multicellular actin star network underpins epithelial organization and connectivity
Barai, A.; Soleilhac, M.; Xi, W.; Lin, S.-Z.; Karnat, M.; Bazellieres, E.; Richelme, S.; Berrebi, D.; Ruemmele, F.; Thery, M.; Rupprecht, J.-F.; Delacour, D.
10.1101/2024.07.26.605277 — cell biology — Posted on 2024-07-26
739 FZD2 inhibits YAP and prevents cell cycle reentry in adult murine cardiomyocytes
Bisson, J. A.; Quijada, P. J.; Wang, Y. T.; Lighthouse, J. K.; Helt, J. C.; Kim, E.; Morrisey, E. E.; Brookes, P. S.; Small, E. M.; Cohen, E. D.
10.1101/2024.07.26.605158 — cell biology — Posted on 2024-07-26
743 Fully Automated MRI-based Analysis of the Locus Coeruleus in Aging and Alzheimer's Disease Dementia using ELSI-Net
Dünnwald, M.; Krohn, F.; Sciarra, A.; Sarkar, M.; Schneider, A.; Fliessbach, K.; Kimmich, O.; Jessen, F.; Rostamzadeh, A.; Glanz, W.; Incesoy, E.; Teipel, S.; Kilimann, I.; Goerss, D.; Spottke, A.; Brustkern, J.; Heneka, M.; Brosseron, F.; Lüsebrink, F.; Hämmerer, D.; Düzel, E.; Tönnies, K.; Oeltze-Jafra, S.; Betts, M. J.
10.1101/2024.07.26.605356 — bioinformatics — Posted on 2024-07-26
747 Decoding protein phosphorylation during oocyte meiotic divisions using phosphoproteomics
Peshkin, L.; Daldello, E. M.; Van Itallie, E. S.; Sonnett, M.; Kreuzer, J.; Haas, W.; Kirschner, M. W.; Jessus, C.
10.1101/2024.07.26.605364 — developmental biology — Posted on 2024-07-26
749 Bifunctional probes reveal the rules of intracellular ether lipid transport
Böhlig, K.; Iglesias-Artola, J. M.; Lennartz, H. M.; Link, A. C.; Drobot, B.; Nadler, A.
10.1101/2024.07.26.605283 — cell biology — Posted on 2024-07-26
750 Reticulon dependent ER-phagy mediates adaptation to heat stress in Caenorhabditis elegans
Scarcelli, V.; Serot, C.; Pouget, A.; Largeau, C.; Sagot, A.; El-Hachimi, K.; Dupuy, D.; Culetto, E.; Lefebvre, C.; Legouis, R.
10.1101/2024.07.26.605287 — cell biology — Posted on 2024-07-26
751 Equine piroplasmosis in different geographical areas in France: prevalence heterogeneity of asymptomatic carriers and low genetic diversity of Theileria equi and Babesia caballi
Jouglin, M.; Bonsergent, C.; de la Cotte, N.; Mege, M.; Bizon, C.; Courouce, A.; Lallemand, E.; Leblond, A.; Lemonnier, L.; Leroux, A.; Marano, I.; Muzard, A.; Quere, E.; Toussaint, M.; Agoulon, A.; Malandrin, L.
10.1101/2024.07.26.605244 — microbiology — Posted on 2024-07-26
753 Epithelial memory after respiratory viral infection results in long-lasting enhancement of antigen presentation
Janas, P. P.; T'Jonck, W.; Burgess, M.; Chauche, C.; Vermeren, M.; Lucas, C.; Bain, C. C.; Illingworth, R. S.; Roberts, E. W.; McSorley, H. J.; Schwarze, J.
10.1101/2024.07.26.605255 — immunology — Posted on 2024-07-26
755 Episodic rhythmicity is generated by a distributed neural network in the developing mammalian spinal cord
Milla-Cruz, J. J.; Lognon, A. P.; Tran, M. A.; Di Vito, S. A.; Loer, C.; Shonak, A.; Broadhead, M. J.; Miles, G. B.; Sharples, S. A.; Whelan, P. J.
10.1101/2024.07.26.605187 — neuroscience — Posted on 2024-07-26
758 Horizontal transfer of nuclear DNA in transmissible cancer
Gori, K. C.; Baez-Ortega, A.; Strakova, A.; Stammnitz, M. R.; Wang, J.; Chan, J.; Hughes, K.; Belkhir, S.; Hammel, M.; Moralli, D.; Bancroft, J.; Drydale, E.; Allum, K. M.; Brignone, M. V.; Corrigan, A. M.; de Castro, K. F.; Donelan, E. M.; Faramade, I. A.; Hayes, A.; Ignatenko, N.; Karmacharya, R.; Koenig, D.; Lanza-Perea, M.; Lopez Quintana, A. M.; Meyer, M.; Neunzig, W.; Pedraza-Ordonez, F.; Phuentshok, Y.; Phuntsho, K.; Ramirez-Ante, J. C.; Reece, J. F.; Schmeling, S. K.; Singh, S.; Tapia Martinez, L. J.; Taulescu, M.; Thapa, S.; Thapa, S.; van der Wel, M. G.; Wehrle-Martinez, A. S.; Strat
10.1101/2024.07.26.604742 — cancer biology — Posted on 2024-07-26
761 Conformational dynamics and asymmetry in multimodal inhibition of membrane-bound pyrophosphatases
Vidilaseris, K.; Ma, Y.; Hardman, K.; Johansson, N. G.; De Castro Ribeiro, O. M.; Yli-Kauhaluoma, J.; Xhaard, H.; Jeuken, L. J. C.; Brookfield, A.; Bowen, A.; Liu, J.; -, ; Shah, A.; Pliotas, C.
10.1101/2024.07.26.605302 — biochemistry — Posted on 2024-07-26
764 Multiple variants of IncF plasmid alleles discovered within single bacterial cells challenge previous assumptions
Ruzickova, M.; Palkovicova, J.; Papousek, I.; Cummins, M. L.; Djordjevic, S. P.; Dolejska, M.
10.1101/2024.07.26.605309 — genomics — Posted on 2024-07-26
765 Environmentally-mediated selection parallels population divergence across a chimpanzee subspecies contact zone
Mitchell, M. W.; Alexander, W.; Mitchell, D. V.; Freedman, A. H.; Dordel, J.; Harrigan, R. J.; Sacan, A.; Kentatchime, F.; Featherstone, B. S.; Abwe, E. E.; Sesink Clee, P. R.; Abwe, A. E.; Locatelli, S.; Morgan, B. J.; Fosso, B.; Fotso, R.; Tishkoff, S. A.; Eichler, E. E.; Anthony, N. M.; Smith, T. B.; Gonder, M. K.
10.1101/2024.07.26.605171 — genomics — Posted on 2024-07-26
766 CO-OPTION OF NECK MUSCLES SUPPORTED THE VERTEBRATE WATER-TO-LAND TRANSITION
Heude, E.; Dutel, H.; Sanchez-Garrido, F.; Prummel, K. D.; Lalonde, R.; Lam, F.; Mosimann, C.; Herrel, A.; Tajbakhsh, S.
10.1101/2024.07.26.605297 — evolutionary biology — Posted on 2024-07-26
767 PLK-1 regulates MEX-1 polarization in the C. elegans zygote
Kim, A. J.; Miller, S. I.; Greiner, E. C.; Kettenbach, A. N.; Griffin, E. E.
10.1101/2024.07.26.605193 — developmental biology — Posted on 2024-07-26
768 Global coordination of protrusive forces in migrating immune cells
Reis-Rodrigues, P.; Canigova, N.; Avellaneda, M. J.; Gaertner, F.; Vaahtomeri, K.; Riedl, M.; Merrin, J.; Hauschild, R.; Fukui, Y.; Garcia, A. J.; Sixt, M.
10.1101/2024.07.26.605242 — cell biology — Posted on 2024-07-26
772 Partial redundancy buffers deleterious effects of mutating DNA methyltransferase 1-1 (MET1-1) in polyploid wheat
Burrows, S.; Dorussen, D.; Crudgington, J.; Di Santolo, G.; Simmonds, J.; Catoni, M.; Borrill, P.
10.1101/2024.07.26.605257 — plant biology — Posted on 2024-07-26
773 PRAME expression in melanoma is negatively regulated by TET2-mediated DNA hydroxymethylation
Fang, R.; Vallius, T.; Zhang, A.; Van Cura, D.; Alicandri, F.; Fischer, G.; Draper, E.; Xu, S.; Pelletier, R.; Katsyv, I.; Sorger, P. K.; Murphy, G. F.; Lian, C. G.
10.1101/2024.07.26.605293 — cancer biology — Posted on 2024-07-26
775 A non-autonomous protein quality control mechanism targeting tau aggregate propagation
Bluemke, A.; Hagemeier, B.; Ripkens, K.; Schulze, N.; Strzala, M.; Koci, M.; Kaschani, F.; Kaiser, M.; Erkelenz, M.; Schluecker, S.; Merdanovic, M.; Poepsel, S.; Hellerschmied, D.; Burston, S.; Ehrmann, M.
10.1101/2024.07.26.605305 — biochemistry — Posted on 2024-07-26
777 Phylogenomics resolves the relationship and the evolutionary history of planthoppers (Insecta: Hemiptera: Fulgoromorpha)
Deng, J.; Stroinski, A.; Szwedo, J.; Ghanavi, H. R.; Yapar, E.; Franco, D. C.; Prus-Frankowska, M.; Michalik, A.; Wahlberg, N.; Lukasik, P.
10.1101/2024.07.26.605304 — evolutionary biology — Posted on 2024-07-26
778 Extensive haplotype diversity in a butterfly colour pattern supergene is fuelled by incomplete recombination suppression
De-Kayne, R.; Gordon, I. J.; Terblanche, R. F.; Collins, S.; Omufwoko, K. S.; Martins, D. J.; Martin, S. H.
10.1101/2024.07.26.605145 — evolutionary biology — Posted on 2024-07-26
780 Dynamics of influenza transmission in vampire bats revealed by longitudinal monitoring and a large-scale anthropogenic perturbation
Griffiths, M. E.; Broos, A.; Morales, J.; Tu, I.-T.; Bergner, L.; Behdenna, A.; Valderrama, W.; Tello, C.; Carrera, J. E.; Recuenco, S.; Streicker, D. G.; Viana, M.
10.1101/2024.07.26.605290 — ecology — Posted on 2024-07-26
781 Avian-restrict Salmonella transition to endemicity is accompanied by localized resistome adaptation
Jia, C.; Huang, C.; Zhou, H.; Zhou, X.; Wang, Z.; Siddique, A.; Kang, X.; Cao, Q.; Huang, Y.; He, F.; Li, Y.; Yue, M.
10.1101/2024.07.26.605275 — microbiology — Posted on 2024-07-26
782 Early life microbial succession in the gut follows common patterns in humans across the globe
Fahur Bottino, G.; Bonham, K. S.; Patel, F.; McCann, S.; Zieff, M.; Naspolini, N.; Ho, D.; Portlock, T.; Joos, R.; Midani, F. S.; Schüroff, P.; Das, A.; Shennon, I.; Wilson, B. C.; O'Sullivan, J. M.; Britton, R. A.; Murray, D. M.; Kiely, M. E.; Taddei, C. R.; Beltrao-Braga, P. C.; Campos, A. C.; Polanczyk, G. V.; Huttenhower, C.; Donald, K. A.; Klepac-Ceraj, V.
10.1101/2024.07.25.605223 — microbiology — Posted on 2024-07-26
783 A new regulator of sporulation sheds light on spore morphogenesis and ballistospory in mushroom-forming fungi
Hou, Z.; Meretenyi, Z.; Yang, Y.; Zhang, Y.; Csernetics, A.; Balint, B.; Hegedus, B.; Foldi, C.; Wu, H.; Kristoffy, Z.; Abraham, E.; Miklovics, N.; Viragh, M.; Liu, X.-B.; Zsibrita, N.; Lipinszki, Z.; Karcagi, I.; Gao, W.; Nagy, L. G.
10.1101/2024.07.26.604922 — microbiology — Posted on 2024-07-26
791 An aging-sensitive compensatory secretory phospholipase that confers neuroprotection and cognitive resilience
Vicidomini, C.; Goode, T. D.; McAvoy, K.; Yu, R.; Beveridge, C.; Iyer, S.; Victor, M. B.; Leary, N.; Evans, L.; Steinbaugh, M. J. B.; Lai, Z. W.; Lyon, M. C.; Silvestre, M. R. F. S.; Bonilla, G.; Sadreyev, R. I.; Walther, T. C.; Sui, S. H.; Saido, T.; Yamamoto, K.; Murakami, M.; Tsai, L.-H.; Chopra, G.; Sahay, A.
10.1101/2024.07.26.605338 — neuroscience — Posted on 2024-07-26
793 Structured flexibility in recurrent neural networks via neuromodulation
Costacurta, J. C.; Bhandarkar, S.; Zoltowski, D. M.; Linderman, S. W.
10.1101/2024.07.26.605315 — neuroscience — Posted on 2024-07-26
794 Engineering anti-amyloid antibodies with transferrin receptor targeting improves safety and brain biodistribution
Pizzo, M. E.; Plowey, E. D.; Khoury, N.; Kwan, W.; Abettan, J.; DeVos, S. L.; Discenza, C. B.; Earr, T.; Joy, D.; Lye-Barthel, M.; Roche, E.; Chan, D.; Dugas, J. C.; Gadkar, K.; Meisner, R.; Sebalusky, J.; Silva Amaral, A. C.; Becerra, I.; Chau, R.; Chow, J.; Clemens, A. J.; Dennis, M. S.; Duque, J.; Fusaro, L.; Getz, J. A.; Kariolis, M. S.; Kim, D. J.; Leung, A. W.-S.; Nguyen, H. N.; Thomsen, E. R.; Sanchez, P. E.; Shan, L.; Silverman, A. P.; Solanoy, H.; Tong, R.; Calvert, M. E. K.; Watts, R. J.; Thorne, R. G.; Weinreb, P. H.; Walsh, D. M.; Lewcock, J. W.; Bussiere, T.; Zuchero, Y. J. Y.
10.1101/2024.07.26.604664 — neuroscience — Posted on 2024-07-26
795 Olfactory projection neuron rewiring in the brain of an ecological specialist
Duerr, B. R.; Bertolini, E.; Takagi, S.; Pascual, J.; Abuin, L.; Lucarelli, G.; Benton, R.; Auer, T. O.
10.1101/2024.07.26.605288 — neuroscience — Posted on 2024-07-26
797 In vivo analysis of the relationship between CP26 and qE-type NPQ via higher-order Arabidopsis cp26 mutants
Kromdijk, J.; Walter, J.; Patel-Tupper, D.; Lam, L.; Ma, A.; Taylor, G.; Fleming, G.; Niyogi, K. K.
10.1101/2024.07.26.605339 — plant biology — Posted on 2024-07-26
798 Adaptive resistance to FLT3 inhibitors is potentiated by ROS-driven DNA repair signalling
Staudt, D. E.; Germon, Z. P.; Mannan, A.; McLachlan, T.; Murray, H. C.; Duchatel, R. J.; Thomas, B. C.; Beitaki, T.; McEwen, H. P.; Persson, M. L.; Calvert, L.; Findlay, I. J.; Jackson, E. R.; Smith, N. D.; Skerrett-Byrne, D. A.; Mossman, D.; Nixon, B.; De Iullis, G.; Douglas, A. M.; Enjeti, A. K.; Sillar, J. R.; Chamberlain, J.; Alvaro, F.; Wei, A. H.; Connerty, P.; Verrills, N.; Dun, M. D.
10.1101/2024.07.26.605229 — cancer biology — Posted on 2024-07-26
800 Competitive modulation of Kv1.2 gating by LMAN2 and Slc7a5
Das, D.; Lamothe, S. M.; Wong, A. A.; Baronas, V. A.; Kurata, H. T.
10.1101/2024.07.25.605230 — biophysics — Posted on 2024-07-26
813 Emissions of climate-altering species from open vegetation fires in the Mediterranean region
Hundal, R. A.; Annadate, S.; Cesari, R.; Collalti, A.; Maione, M.; Cristofanelli, P.
10.1101/2024.07.26.605246 — ecology — Posted on 2024-07-26
814 Asynchronous mouse embryo polarization leads to heterogeneity in cell fate specification
Lamba, A.; Zhu, M.; Meglicki, M.; Czukiewska, S.; Balasubramaniam, L.; Hadas, R.; Weishaupt, N.; Patel, E.; Kavanagh, Y. H.; Wang, R.; Jing, N.; Zernicka-Goetz, M.
10.1101/2024.07.26.605266 — developmental biology — Posted on 2024-07-26
815 Identification of a novel myosin antigen activating CD8+ T cells in C57BL/6 mice
Richter, L.; Bauer, M.; Bernsen, C.; Vogel, E.; Mahmud, Z.; Saliba, A.-E.; Schulz, R.; Frantz, S.; Ashour, D.; Ramos, G. C.
10.1101/2024.07.26.605251 — immunology — Posted on 2024-07-26
816 Specific pre-plasma cell states and local proliferation at the dark zone - medulla interface characterize germinal center-derived plasma cell differentiation in lymph node
Binet, L.; Dong, C.; Attaf, N.; Gil, L.; Fallet, M.; Boudier, T.; Escaliere, B.; Chasson, L.; Siret, C.; van de Pavert, S. A.; Navarro, J.-M.; Milpied, P.
10.1101/2024.07.26.605240 — immunology — Posted on 2024-07-26
817 PD-1 negatively regulates helper T cell differentiation into Th2
Tajima, M.; Ikuta, N.; Nakajima, Y.; Suzuki, K.; Tokumaru, Y.; Li, P.; Kiyonari, H.; Honjo, T.; Ohta, A.
10.1101/2024.07.26.605269 — immunology — Posted on 2024-07-26
818 DOCK8 regulates a mechanosensitive actin redistribution that maintains immune cell cohesion and protects the nucleus during migration
Shen, C.; Postat, J.; Cerf, A.; Merino, M.; Bhagrath, A.; Patel, D.; Luo, V.; Abu-Thuraia, A.; Schneider, C.; Sharma, A.; Suh, W.-K.; Ehrlicher, A.; Cote, J.-F.; Mandl, J. N.
10.1101/2024.07.26.605273 — immunology — Posted on 2024-07-26
819 A single microRNA miR-195 rescues the arrested B cell development induced by EBF1 deficiency
Miyatake, Y.; Ikawa, T.; Yanagiya, R.; Kotaki, R.; Kameda, K.; Nasu, R. K.; Okuyama, K.; Hirano, K.-i.; Hosokawa, H.; Hozumi, K.; Ohtsuka, M.; Kisikawa, T.; Shibata, C.; Otsuka, M.; Maruyama, R.; Ando, K.; Kurosaki, T.; Kawamoto, H.; Kotani, A.
10.1101/2024.07.26.605276 — immunology — Posted on 2024-07-26
820 CD11b suppresses TLR7-driven inflammatory signaling to protect against lupus nephritis
Li, X.; Villanueva, V.; Jimenez, V.; Nguyen, B.; Chauhan, N. R.; Khan, S. Q.; Alzahrani, K.; Wei, H.; Cimbaluk, D. J.; Wei, D. C.; Jolly, M.; Lopez-Rodiguez, D.; Pineda, S. B.; Barbosa, A.; Faridi, H. M.; Reiser, J.; Niewold, T. B.; Gupta, V.
10.1101/2024.07.26.605143 — immunology — Posted on 2024-07-26
822 Guided by touch: Tactile Cues in Hand Movement Control
Vlachou, M. E.; Legros, J.; Sellin, C.; Paleressompoulle, D.; Massi, F.; Simoneau, M.; Mouchnino, L.; Blouin, J.
10.1101/2024.07.26.605248 — neuroscience — Posted on 2024-07-26
825 Dose-related Mutagenic and Clastogenic Effects of Benzofluoranthene in Mouse Somatic Tissues Detected by Duplex Sequencing and the Micronucleus Assay
Schuster, D. M.; LeBlanc, D. P. M.; Zhou, G.; Meier, M. J.; Dodge, A. E.; White, P. A.; Long, A. S.; Williams, A.; Hobbs, C.; Diesing, A.; Smith-Roe, S. L.; Salk, J. J.; Marchetti, F.; Yauk, C. L.
10.1101/2024.07.26.605228 — pharmacology and toxicology — Posted on 2024-07-26
826 Direct inference of the distribution of fitness effects of spontaneous mutations from recombinant inbred C. elegans mutation accumulation lines
Crombie, T. A.; Rajaei, M.; Saxena, A. S.; Johnson, L. M.; Saber, S.; Tanny, R. E.; Ponciano, J. M.; Andersen, E. C.; Zhou, J.; Baer, C. F.
10.1101/2024.05.08.593038 — evolutionary biology — Posted on 2024-07-26
828 Genomic Epidemiology of Monkeypox Virus During the 2022 Outbreak in New York City
Akther, S.; Su, M.; Wang, J. C.; Amin, H.; Taki, F.; De La Cruz, N.; Chowdhury, M.; Clabby, T.; Kopping, E.; Ruiz, V. E.; Leelawong, M.; Latash, J.; Johnson, K.; Baumgartner, J.; Wong, M.; Olsen, A.; Fowler, R. C.; Pekar, J. C.; Havens, J. L.; Vasylyeva, T. I.; Wertheim, J. O.; Hughes, S.; Omoregie, E.
10.1101/2024.07.23.604793 — genomics — Posted on 2024-07-26
830 The valine-arginine dipeptide repeat protein encoded by mammalian telomeric RNA appears highly expressed in mitosis and may repress global translation
Griffith, J. D.; Willcox, S.; Mills, C. A.; Herring, L. E.; Anton, E.; Cho, S.-j.; Lee, H.; meyer, C.; Al-Turki, T.; Mantri, V.
10.1101/2024.07.24.604971 — molecular biology — Posted on 2024-07-26
832 The divergence of DHN-derived melanin pathways in Metarhizium robertsii
Xie, L.; Liu, Y.; Zhang, Y.; Chen, K.; Yue, Q.; Wang, C.; Dun, B.; Xu, Y.; Zhang, L.
10.1101/2024.07.25.605210 — microbiology — Posted on 2024-07-26
833 CD103+ Dendritic Cell - Fibroblast Crosstalk via TLR9 and AHR Signaling Drives Lung Fibrogenesis
Carter, H.; Medina Costa, R.; Bame, M.; Gilchrist, T.; Emch, C.; Adams, T.; Linderholm, A.; Oldham, J. M.; Noth, I.; Kaminski, N.; Moore, B. B.; Gurczynski, S. J.
10.1101/2024.03.15.584457 — immunology — Posted on 2024-07-26
836 An Orthogonal T7 Replisome for Continuous Hypermutation and Accelerated Evolution in E. coli
Diercks, C. S.; Sondermann, P.; Rong, C.; Dik, D. A.; Gillis, T. G.; Ban, Y.; Schultz, P. G.
10.1101/2024.07.25.605042 — synthetic biology — Posted on 2024-07-26
837 Development and Assessment of a Sustainable PhD Internship Program Supporting Diverse Biomedical Career Outcomes
Brandt, P. D.; Whittington, D.; Wood, K. D.; Holmquist, C. E.; Nogueira, A. T.; Gaines, C. H.; Brennwald, P. J.; Layton, R. L.
10.1101/2023.07.13.548912 — scientific communication and education — Posted on 2024-07-26
839 Alleviation of salt stress in strawberries by hydrogen-rich water: physiological, transcriptomic and metabolomic responses
Wang, R.; Chu, S.; Zhang, D.; Zhang, X.; Chi, Y.; Ma, X.; Chen, X.; Yang, H.; Ding, W.; Zhao, T.; Ren, Y.; Yang, X.; Zhou, P.
10.1101/2024.07.25.605184 — physiology — Posted on 2024-07-26
840 Chromatin Remodeling by the Histone Methyltransferase SETD2 Drives Lipotoxic Injury in Cardiometabolic Heart Failure with Preserved Ejection Fraction
Ambrosini, S.; Costantino, S.; Mohammed, S. A.; Gorica, E.; Herwig, M.; van Heerebeek, L.; Mengozzi, A.; Karsai, G.; Hornemann, T.; Dzemali, O.; Ruschitzka, F.; Hamdani, N.; Paneni, F.
10.1101/2024.07.25.605217 — physiology — Posted on 2024-07-26
841 Epigenetic mechanisms controlling human leukemia stem cells and therapy resistance
Takao, S.; Morell, V.; Uni, M.; Slavit, A.; Rha, S.; Cheng, S.; Schmalbrock, L. K.; Brown, F. C.; Calabuig, S. B.-; Koche, R.; Velten, L.; Kentsis, A.
10.1101/2022.09.22.509005 — cancer biology — Posted on 2024-07-26
844 Evaluating the effects of archaic protein-altering variants in living human adults
Molz, B.; Lana Alberro, M.; Eising, E.; Schijven, D.; Alagöz, G.; Francks, C.; Fisher, S. E.
10.1101/2024.07.05.602242 — genetics — Posted on 2024-07-26
846 Heterochrony in orthodenticle expression is associated with ommatidial size variation between Drosophila species
Torres-Oliva, M.; Buchberger, E.; Buffry, A. D.; Kittelmann, M.; Guerrero, G.; Sumner-Rooney, L.; Gaspar, P. M. C.; Bullinger, G. C.; Figueras Jimenez, J.; Casares, F.; Arif, S.; Nunes, D. S.; Posnien, N.; McGregor, A. P.; Almudi, I.
10.1101/2021.03.17.435774 — evolutionary biology — Posted on 2024-07-26
848 Partitioning changes in ecosystem productivity by effects of species interactions in biodiversity experiments
Tao, J.; Nock, C.; Searle, E. B.; Huang, s.; Man, R.; Yang, H.; Freschet, G.; Violle, C.; Zheng, J.
10.1101/2024.03.30.587418 — ecology — Posted on 2024-07-26
849 The collective application of shorebird tracking data to conservation
Harrison, A.-L.; Stenzel, C.; Anderson, A.; Howell, J.; Lanctot, R. B.; Aikens, M.; Aldabe, J.; Berigan, L. A.; Bety, J.; Blomberg, E.; Bosi de Almeida, J.; Boyce, A. J.; Bradley, D. W.; Brown, S.; Carlisle, J.; Cheskey, E.; Christie, K.; Christin, S.; Clay, R.; Dayer, A.; Deppe, J. L.; English, W.; Flemming, S. A.; Gilg, O.; Gilroy, C.; Heath, S.; Hill, J. M.; Hipfner, J. M.; Johnson, J. A.; Johnson, L.; Kempenaers, B.; Knaga, P.; Kwon, E.; Lagasse, B. J.; Lamarre, J.-F.; Latty, C.; Leandri-Breton, D.-J.; Lecomte, N.; Loring, P.; McGuire, R.; Moorhead, S.; Navedo, J. G.; Newstead, D.; Nol, E.
10.1101/2024.01.30.576574 — ecology — Posted on 2024-07-26
850 Multi-species genome-wide CRISPR screens identify GPX4 as a conserved suppressor of cold-induced cell death
Lam, B.; Kajderowicz, K. M.; Keys, H. R.; Roessler, J. M.; Frenkel, E. M.; Kirkland, A.; Bisht, P.; El-Brolosy, M. A.; Jaenisch, R.; Bell, G. W.; Weissman, J. S.; Griffith, E. C.; Hrvatin, S.
10.1101/2024.07.25.605098 — cell biology — Posted on 2024-07-26
851 Mobile Integrons Encode Phage Defense Systems
Kieffer, N.; Hipolito, A.; Blanco, P.; Delobelle, T.; Ortiz-Miravalles, L.; Ojeda, F. M.; Jove, T.; Jurenas, D.; Garcia-Quintanilla, M.; Domingo-Calap, P.; Escudero, J. A.
10.1101/2024.07.02.601719 — microbiology — Posted on 2024-07-26
852 A mechanistic step in the genesis of secondary chromosomes from plasmids
Fournes, F.; Campos, M.; Cury, J.; Schiavon, C.; Pages, C.; Touchon, M.; Rocha, E. P. C.; Rousseau, P.; Cornet, F.
10.1101/2024.04.05.588136 — microbiology — Posted on 2024-07-26
855 Lack of Single Amino Acids Transcriptionally Remodels Sensory Systems to Enhance the Intake of Protein and Microbiota
Ezra, G.; Henriques, S. F.; Muench, D.; Francisco, A. P.; Baltazar, C.; Elias, A. P.; Deplancke, B.; Ribeiro, C.
10.1101/2024.07.23.604616 — neuroscience — Posted on 2024-07-26
856 Genetic variance in the murine defensin locus modulates glucose homeostasis
Masson, S. W. W.; Simpson, R. C.; Cutler, H. B.; Carlos, P. W.; Marian, O. C.; Potter, M.; Madsen, S.; Cooke, K. C.; Craw, N. R.; Fuller, O. K.; Harney, D. J.; Larance, M.; Cooney, G. J.; Morahan, G.; Shanahan, E. R.; Hodgkins, C.; Payne, R. J.; Stöckli, J.; James, D. E.
10.1101/2024.07.25.605202 — systems biology — Posted on 2024-07-26
857 Molecular mimicry of a pathogen virulence target by a plant immune receptor
Gomez De La Cruz, D.; Zdrzałek, R.; Banfield, M. J.; Talbot, N. J.; Moscou, M. J.
10.1101/2024.07.26.605320 — plant biology — Posted on 2024-07-26
858 Direct measurements of luminal Ca2+ with endo-lysosomal GFP-aequorin (ELGA) reveal functional IP3 receptors
Calvo, B.; Torres-Vidal, P.; Delrio, A.; Rodriguez, C.; Aulestia, F.; Rojo-Ruiz, J.; McVeigh, B. M.; Moiseenkova-Bell, V.; Yule, D. I.; Garcia-Sancho, J.; Patel, S.; Alonso, M. T.
10.1101/2023.07.11.547422 — physiology — Posted on 2024-07-26
860 3D osteocyte lacunar morphometry of human bone biopsies with high resolution microCT: from monoclonal gammopathy to newly diagnosed multiple myeloma
Moreno-Jimenez, I.; Heinig, S.; Heras, U.; Maichl, D. S.; Strifler, S.; Leich, E.; Blouin, S.; Fratzl, P.; Fratzl-Zelman, N.; Jundt, F.; Cipitria, A.
10.1101/2023.07.12.548656 — bioengineering — Posted on 2024-07-26
865 Microbes with higher metabolic independence are enriched in human gut microbiomes under stress
Veseli, I.; Chen, Y. T.; Schechter, M. S.; Vanni, C.; Fogarty, E. C.; Watson, A. R.; Jabri, B. A.; Blekhman, R.; Willis, A. D.; Yu, M. K.; Fernandez-Guerra, A.; Fussel, J.; Eren, A. M.
10.1101/2023.05.10.540289 — microbiology — Posted on 2024-07-26
867 Grasp Orientation in Ambiguous Settings is Sensitive to Prior Object Motion
Maffitt, N. J.; Cairns, E. G.; Wozna, J.; Soteropoulos, D. S.; Kraskov, A.
10.1101/2023.11.20.567846 — neuroscience — Posted on 2024-07-26
868 Moderate-term dimethyl fumarate treatment reduces pathology of dystrophic skeletal and cardiac muscle in a mouse model
Kourakis, S.; Timpani, C. A.; Bagaric, R. M.; Qi, B.; Ali, B. A.; Boyer, R.; Spiesberger, G.; Kandhari, N.; Peterson, A. L.; Debrincat, D.; Yates, T. J.; Yan, X.; Kuang, J.; de Haan, J. B.; Stupka, N.; Nijagal, B.; Deveson-Lucas, D.; Fischer, D.; Rybalka, E.
10.1101/2024.07.13.601627 — pathology — Posted on 2024-07-26
869 Transfer RNA acetylation regulates in vivo mammalian stress signaling
Thalalla Gamage, S.; Khoogar, R.; Howpay Manage, S. A.; Crawford, M. C.; Georgeson, J.; Polevoda, B. V.; Sanders, C.; Lee, K. A.; Nance, K. D.; Iyer, V.; Kustanovich, A.; Perez, M.; Thu, C. T.; Nance, S. R.; Miller, C. N.; Holewinski, R. J.; Meyer, T.; Koparde, V.; Yang, A.; Jailwala, P.; Nguyen, J. T.; Andresson, T.; Mock, B. A.; Gu, S.; Edmondson, E. F.; Difilippantonio, S.; Chari, R.; Schwartz, S.; O'Connell, M. R.; Wu, C. C.-C.; Meier, J. L.
10.1101/2024.07.25.605208 — developmental biology — Posted on 2024-07-26
870 Decoding RNA Metabolism by RNA-linked CRISPR Screening in Human Cells
Nugent, P. J.; Park, H.; Wladyka, C. L.; Chen, K. Y.; Bynum, C.; Quarterman, G.; Hsieh, A. C.; Subramaniam, A. R.
10.1101/2024.07.25.605204 — molecular biology — Posted on 2024-07-26
871 Adipogenin Dictates Adipose Tissue Expansion by Facilitating the Assembly of a Dodecameric Seipin Complex
Li, C.; Sun, X.-N.; Funcke, J.-B.; Vanharanta, L.; Joffin, N.; Li, Y.; Prasanna, X.; Paredes, M.; Joung, C.; Gordillo, R.; voros, C.; Kulig, W.; Straub, L.; Chen, S.; Velasco, J.; Cobb, A.; Padula, D.; Wang, M.-Y.; Onodera, T.; Varlamov, O.; Li, Y.; Liu, C.; Nawrocki, A.; Zhao, S.; Oh, D. Y.; Wang, Z.; Goodman, J.; Wynn, R. M.; Vattulainen, I.; Han, Y.; Ikonen, E.; Scherer, P. E.
10.1101/2024.07.25.605195 — cell biology — Posted on 2024-07-26
872 Interpretable representation learning for 3D multi-piece intracellular structures using point clouds
Vasan, R.; Ferrante, A.; Borensztejn, A.; Frick, C. L.; Gaudreault, N.; Mogre, S. S.; Morris, B.; Pires, G. G.; Rafelski, S. M.; Theriot, J. A.; Viana, M. P.
10.1101/2024.07.25.605164 — cell biology — Posted on 2024-07-26
873 CRISPR screens reveal ZBTB17/MIZ1 as a peroxisome regulator
Liu, H.; Chen, X.; Wang, H.; Zhuang, G.; Zhu, Z.-J.; Zhuang, M.
10.1101/2024.07.25.605214 — cell biology — Posted on 2024-07-26
874 Second generation of LNP based mRNA vaccine leads to a T-cell-inflamed tumor microenvironment favorable for improving PD-1/PD-L1 blocking therapy and long-term immunity in a cold tumor model
Fournier, C.; Mercey-Ressejac, M.; Derangere, V.; Al Kadi, A.; Rageot, D.; Charrat, C.; Leroy, A.; Escude, M.; Escaich, S.; Ghiringhelli, F.; Decaens, T.; Navarro, F. P.; Jouvin-Marche, E.; Marche, P. N.
10.1101/2024.07.24.604918 — immunology — Posted on 2024-07-26
877 The Genetic Architecture of the Human Corpus Callosum and its Subregions
Bhatt, R.; Gadewar, S. P.; Shetty, A. K.; Ba Gari, I.; Haddad, E.; Javid, S.; Ramesh, A.; Nourollahimoghadam, E.; Zhu, A. H.; de Leeuw, C.; Thompson, P. M.; Medland, S. E.; Jahanshad, N.
10.1101/2024.07.22.603147 — neuroscience — Posted on 2024-07-26
880 Re-analysis of mobile mRNA datasets highlights challenges in the detection of mobile transcripts from short-read RNA-Seq data
Paajanen, P.; Tomkins, M.; Hoerbst, F.; Veevers, R.; Heeney, M.; Thomas, H. R.; Apelt, F.; Saplaoura, E.; Gupta, S.; Frank, M.; Walther, D. J.; Faulkner, C.; Kehr, J.; Kragler, F.; Morris, R. J.
10.1101/2024.07.25.604588 — plant biology — Posted on 2024-07-26
882 Exploring the impacts of human breast milk functional lipidome on infant health and growth outcomes in early life using lipid bioinformatics
Ganeshalingam, M.; Cheema, S.; Wagner, C. L.; Pham, T. H.; Enstad, S.; Andrews, C.; Grapov, D.; Esposito, F.; Sen, S.; Thomas, R.
10.1101/2024.07.25.605136 — bioinformatics — Posted on 2024-07-26
884 Peer victimization in adolescence alters gene expression and cytokine profiles
Heumann, J.; Cole, S. W.; Eisner, M.; Ribeaud, D.; Gruenblatt, E.; Shanahan, M. J.
10.1101/2024.07.24.604965 — genomics — Posted on 2024-07-26
885 Genomic epidemiology and phenotypic characterisation of Salmonella entericaserovar Panama in Victoria, Australia
Thakur, S.; Baines, S. L.; Sia, C.; Valcanis, M.; Judd, L. M.; Howden, B. P.; Newton, H. J.; Ingle, D. J.
10.1101/2024.07.23.603842 — microbiology — Posted on 2024-07-26
886 WITHDRAWN: IL-17C plays a role in the pathophysiology of acute recurrent tonsillitis
Clapperton, M.; Kunanandam, T.; Florea, C. D.; Cunningham, M. R.; Douglas, C.; McConnell, G.
10.1101/2024.02.08.578879 — immunology — Posted on 2024-07-26
888 Factors behind poor cognitive outcome following a thalamic stroke
Vidal, J. P.; Danet, L.; Arribarat, G.; Pariente, J.; Peran, P.; Albucher, J.-F.; Barbeau, E. J.
10.1101/2024.07.24.604322 — neuroscience — Posted on 2024-07-26
895 Testing the causal impact of amyloidosis on total Tau using a genetically informative sample of adult male twins.
Gillespie, N.; Neale, M. C.; Panizzon, M. S.; McKenzie, R. E.; Tu, X. M.; Reynolds, C. M.; Lyons, M. J.; Rissman, R. A.; Elman, J. A.; Franz, C. E.; Kremen, W. S.
10.1101/2024.07.23.602498 — pathology — Posted on 2024-07-26
900 Genetic variation in the species Arabidopsis thaliana reveals the existence of natural heat resilience factors for meiosis
Zhao, J.; Fu, H.; Wang, Z.; Zhang, M.; Liang, Y.; Cui, X.; Pan, W.; Ren, Z.; Wu, Z.; Zhang, Y.; Gui, X.; Huo, L.; Lei, X.; Wang, C.; Schnittger, A.; Pawlowski, W. P.; Liu, B.
10.1101/2024.07.16.603532 — plant biology — Posted on 2024-07-26
901 Complete genome of the Medicago anthracnose fungus, Colletotrichum destructivum, reveals a mini-chromosome-like region within a core chromosome.
LAPALU, N.; SIMON, A.; Lu, A.; Plaumann, P.-L.; Amselem, J.; Pigne, S.; Auger, A.; Koch, C.; Dallery, J.-F.; O'Connell, R. J.
10.1101/2023.12.16.571984 — genomics — Posted on 2024-07-26
902 Is FAM19A5 an adipokine? Peripheral FAM19A5 in wild-type, FAM19A5 knock-out, and LacZ knock-in mice.
Kwak, H.; Cho, E.-H.; Cho, E. B.; Lee, Y.-N.; Shahapal, A.; Yong, H. J.; Reyes-Alcaraz, A.; Jeong, Y.; Lee, Y.; Lee, M.; Ha, N.; Oh, S.; Lee, J. K.; Lee, W. S.; Kim, W. K.; Hwang, J.-I.; Seong, J. Y.
10.1101/2020.02.19.955351 — genetics — Posted on 2024-07-26
903 Single nuclei transcriptomics reveal the differentiation trajectories of periosteal skeletal/stem progenitor cells in bone regeneration
Perrin, S.; Ethel, M.; Bretegnier, V.; Goachet, C.; Wotawa, C.-A.; Luka, M.; Coulpier, F.; Masson, C.; Menager, M.; Colnot, C.
10.1101/2023.06.23.546220 — cell biology — Posted on 2024-07-26
905 Assemblies, synapse clustering and network topology interact with plasticity to explain structure-function relationships of the cortical connectome
Ecker, A.; Egas Santander, D.; Abdellah, M.; Blanco Alonso, J.; Bolanos-Puchet, S.; Chindemi, G.; Gowri Mariyappan, D. P.; Isbister, J. B.; King, J. G.; Kumbhar, P.; Magkanaris, I.; Muller, E. B.; Reimann, M. W.
10.1101/2023.08.07.552264 — neuroscience — Posted on 2024-07-26
906 Combining systems and synthetic biology for in vivo enzymology
Castano-Cerezo, S.; Chamas, A.; Kulyk, H.; Treitz, C.; Bellvert, F.; Tholey, A.; Galeote, V.; Camarasa, C.; Heux, S.; Garcia-Alles, L. F.; Millard, P.; Truan, G.
10.1101/2024.02.02.578620 — systems biology — Posted on 2024-07-26
910 3D osteocyte lacunar morphometry of human bone biopsies with high resolution microCT: from monoclonal gammopathy to newly diagnosed multiple myeloma
Moreno-Jimenez, I.; Heinig, S.; Heras, U.; Maichl, D. S.; Strifler, S.; Leich, E.; Blouin, S.; Fratzl, P.; Fratzl-Zelman, N.; Jundt, F.; Cipitria, A.
10.1101/2023.07.12.548656 — bioengineering — Posted on 2024-07-26
913 ECM1 Attenuates Hepatic Fibrosis by Interfering with Mediators of Latent TGF-β1 Activation
Link, F.; Li, Y.; Zhao, J.; Munker, S.; Fan, W.; Nwosu, Z.; Yao, Y.; Wang, S.; Huang, C.; Hammad, S.; Liebe, R.; Liu, H.; Shao, C.; Gao, C.; Sun, B.; Torok, N. J.; Ding, H.; Ebert, M.; Weng, H.; Dijke, P. t.; Drasdo, D.; Dooley, S.; Wang, S.
10.1101/2023.12.12.571289 — cell biology — Posted on 2024-07-26
914 An emerging PB2-627 polymorphism increases the pandemic potential of avian influenza virus by breaking through ANP32 host restriction in mammalian and avian hosts
Guo, Y.; Shu, S.; Zhou, Y.; Peng, W.; Jiang, Z.; Li, Y.; Li, T.; Du, F.; Wang, L.; Chen, X.; Dong, J.; Zhao, C.; Wang, M. H.; Sun, Y.; Sun, H.; Lu, L.; Digard, P.; Chang, K.-c.; Yen, H.-L.; Liu, J.; Pu, J.
10.1101/2024.07.03.601996 — microbiology — Posted on 2024-07-26
918 Regenerative human liver organoids (HLOs) in a pillar/perfusion plate for hepatotoxicity assays
Shrestha, S.; Acharya, P.; Kang, S.-Y.; Vanga, M. G.; Lekkala, V. K. R.; Liu, J.; Yang, Y.; Joshi, P.; Lee, M.-Y.
10.1101/2024.03.25.586638 — bioengineering — Posted on 2024-07-26
919 PITPβ promotes COPI vesicle fission through lipid transfer and membrane contact formation
Park, K.; Ju, S.; Choi, H.; Gao, P.; Bang, G.; Choi, J. H.; Jang, J.; Morris, A.; Kang, B.-H.; Hsu, V. W.; Park, S.-Y.
10.1101/2024.05.27.596058 — cell biology — Posted on 2024-07-26
920 Direct RNA sequencing (RNA004) allows for improved transcriptome assessment and near real-time tracking of methylation for medical applications
Hewel, C.; Hofmann, F.; Dietrich, V.; Wierczeiko, A.; Friedrich, J.; Jenson, K.; Muendnich, S.; Diederich, S.; Sys, S.; Schartel, L.; Schweiger, S.; Helm, M.; Lemke, E. A.; Linke, M.; Gerber, S.
10.1101/2024.07.25.605188 — bioinformatics — Posted on 2024-07-25
925 The cold-inducible RNA-binding protein RBM3 stabilises viral mRNA at the cooler temperatures of the upper respiratory tract.
Coutts, H. L.; Turkington, H. L.; Bonazza, S.; Getty, E. M. P. E.; Sukumar, S.; Power, U. F.; Courtney, D. G.
10.1101/2024.07.25.605104 — microbiology — Posted on 2024-07-25
926 Age-related changes in 'cortical' 1/f dynamics are linked to cardiac activity
Schmidt, F.; Danboeck, S. K.; Trinka, E.; Klein, D. P.; Demarchi, G.; Weisz, N.
10.1101/2022.11.07.515423 — neuroscience — Posted on 2024-07-25
927 DNA O-MAP uncovers the molecular neighborhoods associated with specific genomic loci
Liu, Y.; McGann, C. D.; Krebs, M.; Perkins, T. A.; Fields, R.; Camplisson, C. K.; Hsu, C.; Avanessian, S.; Tsue, A. F.; Kania, E. E.; Shechner, D. M.; Beliveau, B. J.; Schweppe, D. K.
10.1101/2024.07.24.604987 — systems biology — Posted on 2024-07-25
929 PGC-1a drives small cell neuroendocrine cancer progression towards an ASCL1-expressing subtype with increased mitochondrial capacity
Varuzhanyan, G.; Chen, C.-C.; Freeland, J.; He, T.; Tran, W.; Song, K.; Wang, L.; Cheng, D.; Xu, S.; Dibernardo, G. A.; Esedebe, F. N.; Bhatia, V.; Han, M.; Abt, E. R.; Park, J. W.; Memarzadeh, S.; Shackelford, D.; Lee, J. K.; Graeber, T.; Shirihai, O.; Witte, O. N.
10.1101/2024.04.09.588489 — cancer biology — Posted on 2024-07-25
934 Cell surface ribonucleoproteins cluster with heparan sulfate to regulate growth factor signaling
Chai, P.; Perr, J.; Kageler, L.; Lebedenko, C. G.; Dias, J. M. L.; Yankova, E.; Esko, J. D.; Tzelepis, K.; Flynn, R. A.
10.1101/2024.07.25.605163 — molecular biology — Posted on 2024-07-25
935 Spotted hyena gut cross-talks:Symbionts modulate mucosal immunity
Veloso Soares, S. P.; JarquinDiaz, V. H.; Veiga, M. M.; Karl, S.; Czirjak, G. A.; Weyrich, A.; Metzger, S.; East, M. L.; Hofer, H.; Heitlinger, E.; Benhaiem, S.; Martins Ferreira, S. C.
10.1101/2024.07.25.605121 — ecology — Posted on 2024-07-25
940 Biom3d, a modular framework to host and develop 3D segmentation methods
Mougeot, G.; Safarbati, S.; Alegot, H.; Pouchin, P.; Field, N.; Almagro, S.; Pery, E.; Probst, A.; Tatout, C.; Evans, D. E.; Graumann, K.; Chausse, F.; Desset, S.
10.1101/2024.07.25.604800 — bioinformatics — Posted on 2024-07-25
942 Bursts of rapid diversification, dispersals out of southern Africa, and two origins of dioecy punctuate the evolution of Asparagus
Bentz, P. C.; Burrows, J. E.; Burrows, S. M.; Mizrachi, E.; Liu, Z.; Yang, J.-B.; Mao, Z.; Popecki, M.; Seberg, O.; Petersen, G.; Leebens-Mack, J.
10.1101/2024.07.25.605174 — evolutionary biology — Posted on 2024-07-25
944 Major change in swine influenza virus diversity in France owing to emergence and widespread dissemination of a newly introduced H1N2 1C genotype in 2020
Richard, G.; Herve, S.; Chastagner, A.; Queguiner, S.; Beven, V.; Hirchaud, E.; Barbier, N.; Gorin, S.; Blanchard, Y.; Simon, G.
10.1101/2024.07.25.605108 — evolutionary biology — Posted on 2024-07-25
946 Substrate stiffness regulates neuronal maturation via Piezo1-mediated TTR activity
Kreysing, E.; Gautier, H.; Humphrey, R. J.; Mooslehner, K. A.; Muresan, L. A.; Haarhoff, D.; Mukherjee, S.; Zhao, X. X.; Winkel, A. K.; Dimitracopoulos, A.; Pillai, E. K.; Karadottir, R. T.; Franze, K.
10.1101/2024.07.25.605128 — developmental biology — Posted on 2024-07-25
948 Local DNA compaction creates TF-DNA clusters that enable transcription
Chabot, N. M.; Purkanti, R.; Del Panta, A.; Dalle Nogare, D.; Oda, H.; Kimura, H.; Jug, F.; Dal Co, A.; Vastenhouw, N. L.
10.1101/2024.07.25.605169 — cell biology — Posted on 2024-07-25
950 Cell surface ribonucleoproteins cluster with heparan sulfate to regulate growth factor signaling
Flynn, R. A.; Chair, P.; Perr, J.; Kageler, L.; Lebedenko, C. G.; Dias, J. M. L.; Yankova, E.; Esko, J. D.; Tzelepis, K.
10.1101/2024.07.25.605163 — molecular biology — Posted on 2024-07-25
952 Altering rRNA 2'O-methylation pattern during neuronal differentiation is regulated by FMRP
D'Souza, M. N.; Gowda, N. K. C.; Hariharan, N.; Qadri, S. W.; Palakodeti, D.; Muddashetty, R. S.
10.1101/2024.07.25.605157 — molecular biology — Posted on 2024-07-25
953 An optimised approach to evaluate variability in gut health markers in healthy adults.
Krüger, K.; Myeonghyun, Y.; van der Wielen, N.; Kok, D.; Hooiveld, G.; Keshtkar, S.; Diepenveen-de Bruin, M.; Balvers, M. G. J.; Grootte Bromhaar, M.; Mudde, K.; Ly, N. T. H. N.; Vermeiren, Y.; de Groot, L. C. P. G. M.; de Vos, R. C. H.; Gonzales, G. B.; Steegenga, W.; van Trijp, M.
10.1101/2024.07.25.604267 — microbiology — Posted on 2024-07-25
954 An orexin-sensitive subpopulation of layer 6 neurons regulates cortical excitability and anxiety behaviour.
Messore, F.; Therpurakal Narayanan, R.; Dufour, J. P.; Hoerder-suabedissen, A.; Guidi, L.; Korrell, K.; Mueller, M.; Lak, A.; Bannerman, D.; Mann, E. O.; Molnar, Z.
10.1101/2024.07.25.605138 — neuroscience — Posted on 2024-07-25
955 Endothelial TRPV4/Cx43 Signaling Complex Regulates Vasomotor Tone in Resistance Arteries
Burboa, P. C.; Gaete, P.; Shu, P.; Araujo, P. A.; Beuve, A.; Contreras, J. E.; Duran, W.; Lillo Gallardo, M. A.
10.1101/2024.07.25.604930 — physiology — Posted on 2024-07-25
956 SAVANA: reliable analysis of somatic structural variants and copy number aberrations in clinical samples using long-read sequencing
Elrick, H.; Sauer, C. M.; Espejo Valle-Inclan, J.; Trevers, K.; Tanguy, M.; Zumalave, S.; De Noon, S.; Muyas, F.; Cascao, R.; Afonso, A.; Amary, F.; Tirabosco, R.; Giess, A.; Freeman, T.; Sosinsky, A.; Piculell, K.; Miller, D. T.; Faria, C. C.; Elgar, G.; Flanagan, A. M.; Cortes-Ciriano, I.
10.1101/2024.07.25.604944 — cancer biology — Posted on 2024-07-25
957 Evaluation of Methodologies in Anti-nephrin Autoantibody Detection
Liu, P.; Liu, S.; Dalal, V.; Lane, J.; Gessaroli, E.; Forte, E.; Gallon, L.; Jin, J.
10.1101/2024.07.25.605154 — biochemistry — Posted on 2024-07-25
960 The axillary lymphoid organ - an external, experimentally accessible immune organ in the zebrafish
Castranova, D.; Kenton, M. I.; Kraus, A.; Dell, C. W.; Park, J. S.; Venero Galanternik, M.; Park, G.; Lumbantobing, D. N.; Dye, L.; Marvel, M.; Iben, J.; Taimatsu, K.; Pham, V.; Willms, R. J.; Blevens, L.; Robertson, T. F.; Hou, Y.; Huttenlocher, A. F.; Foley, E.; Parenti, L. R.; Frazer, J. K.; Narayan, K.; Weinstein, B. M.
10.1101/2024.07.25.605139 — developmental biology — Posted on 2024-07-25
961 The role of dietary patterns in the polarization of angiogenic uterine Natural Killer cells during murine pregnancy
Lopes Salles, E.; Zavan, B.; Cabral Marcelino, R.; Shimaoka Chagas, P.; Mollica do Amarante-Paffaro, A.; Woodham, P.; Baban, B.; Paffaro Junior, V. A.
10.1101/2024.07.25.605132 — immunology — Posted on 2024-07-25
962 Illuminating microbial mat assembly: Cyanobacteria and Chloroflexota cooperate to structure light-responsive biofilms
Bunbury, F.; Rivas, C.; Calatrava, V.; Malkovskiy, A.; Joubert, L.-M.; Parvate, A.; Evans, J. E.; Grossman, A. R.; Bhaya, D.
10.1101/2024.07.24.605005 — microbiology — Posted on 2024-07-25
966 The collective application of shorebird tracking data to conservation
Harrison, A.-L.; Stenzel, C.; Anderson, A.; Howell, J.; Lanctot, R. B.; Aikens, M.; Aldabe, J.; Berigan, L. A.; Bety, J.; Blomberg, E.; Bosi de Almeida, J.; Boyce, A. J.; Bradley, D. W.; Brown, S.; Carlisle, J.; Cheskey, E.; Christie, K.; Christin, S.; Clay, R.; Dayer, A.; Deppe, J. L.; English, W.; Flemming, S. A.; Gilg, O.; Gilroy, C.; Heath, S.; Hill, J. M.; Hipfner, J. M.; Johnson, J. A.; Johnson, L.; Kempenaers, B.; Knaga, P.; Kwon, E.; Lagasse, B. J.; Lamarre, J.-F.; Latty, C.; Leandri-Breton, D.-J.; Lecomte, N.; Loring, P.; McDuffie, L. A.; McGuire, R.; Moorhead, S.; Navedo, J. G.; News
10.1101/2024.01.30.576574 — ecology — Posted on 2024-07-25
968 A comprehensive chemotyping and gonadal regulation of seven kisspeptinergic neuronal populations in the mouse brain
Hernandez, V. S.; Zetter, M. A.; Hernandez-Perez, O. R.; Hernandez-Gonzalez, R.; Camacho-Arroyo, I. S.; Millar, R. P.; Eiden, L. E.; Zhang, L.
10.1101/2024.07.23.604881 — neuroscience — Posted on 2024-07-25
969 Robust proteome profiling of cysteine-reactive fragments using label-free chemoproteomics
Biggs, G. S.; Cawood, E. E.; Vuorinen, A.; McCarthy, W. J.; Wilders, H.; Riziotis, I. G.; van der Zouwen, A. J.; Pettinger, J.; Nightingale, L.; Chen, P.; Powell, A. J.; House, D.; Boulton, S. J.; Skehel, J. M.; Rittinger, K.; Bush, J. T.
10.1101/2024.07.25.605137 — systems biology — Posted on 2024-07-25
970 Drug-loaded nanoparticles for cancer therapy: a high-throughput multicellular agent-based modeling study
Wang, Y.; Bucher, E.; Rocha, H.; Jadhao, V.; Metzcar, J.; Heiland, R.; Frieboes, H. B.; Macklin, P.
10.1101/2024.04.09.588498 — systems biology — Posted on 2024-07-25
974 Cryopreservation of neuroectoderm on a pillar plate and in situ differentiation into human brain organoids
Zolfaghar, M.; Acharya, P.; Joshi, P.; Choi, N. Y.; Shrestha, S.; Lekkala, V. K. R.; Kang, S.-Y.; Lee, M.; Lee, M.-Y.
10.1101/2024.07.25.605147 — bioengineering — Posted on 2024-07-25
977 Intracellular lipopolysaccharide regulates ER remodeling upon bacterial infection
Cheng, Y.-L.; Mello-Vieira, J.; Covarrubias-Pinto, A.; Gonzalez, A.; Kuncha, S. K.; Kew, C.; Zhang, K.; Afzal, M. A.; Diab, N.; Borchert, S.; Chen, W.; Huang, T. C.; Hornef, M.; Huebner, C. A.; Hensel, M.; Dikic, I.
10.1101/2024.07.25.605133 — cell biology — Posted on 2024-07-25
980 Chemokines Kill Bacteria by Binding Anionic Phospholipids without Triggering Antimicrobial Resistance
Pontejo, S. M.; Martinez, S.; Zhao, A.; Barnes, K.; de Anda, J.; Alimohamadi, H.; Lee, E. Y.; Dishman, A. F.; Volkman, B. F.; Wong, G. C. L.; Garboczi, D. N.; Ballesteros, A.; Murphy, P. M.
10.1101/2024.07.25.604863 — microbiology — Posted on 2024-07-25
983 Tripartite interaction of a patescibacterial epibiont, a methylotrophic gammaproteobacterial host and a jumbo phage
Buderka, F.; Lopez-Garcia, P.; Deschamps, P.; Krupovic, M.; Gutierrez-Preciado, A.; Ciobanu, M.; Bertolino, P.; David, G.; Moreira, D.; Jardillier, L.
10.1101/2024.03.08.584096 — microbiology — Posted on 2024-07-25
986 2'-O-Methyl-guanosine 3-base RNA fragments mediate essential natural TLR7/8 antagonism
Alharbi, A.; Sapkota, S.; Zhang, Z.; Jin, R.; Jayasekara, W. S.; Rupasinghe, E.; Speir, M.; Wilkinson-White, L.; Gamsjaeger, R.; Cubeddu, L.; Ellyard, J. I.; Wenholz, D.; McAllan, A.; Rezwan, R.; Ying, L.; Hosseini Far, H.; Bones, J.; He, S.; Yu, D.; Lennox, K.; Hertzog, P. J.; Vinuesa, C.; Behlke, M. A.; Ohto, U.; Laczka, O.; Corry, B.; Shimizu, T.; Gantier, M. P.
10.1101/2024.07.25.605091 — immunology — Posted on 2024-07-25
990 Control of tongue movements by the Purkinje cells of the cerebellum
Hage, P.; Fakharian, M. A.; Shoup, A. M.; Pi, J. S.; Sedaghat-Nejad, E.; Orozco, S. P.; Jang, I. K.; Looi, V.; Arginteanu, T.; Shadmehr, R.
10.1101/2024.07.25.604757 — neuroscience — Posted on 2024-07-25
991 Non-invasive Ultrasound Deep Neuromodulation of the Human Nucleus Accumbens Increases Win-Stay Behaviour
Yaakub, S. N.; Bault, N.; Lojkiewiez, M.; Bellec, E.; Roberts, J.; Philip, N.; Rushworth, M. F.; Fouragnan, E. F.
10.1101/2024.07.25.605068 — neuroscience — Posted on 2024-07-25
992 Modulation of Neuronal Excitability and Plasticity by BHLHE41 Conveys Lithium Non-Responsiveness
Rossner, M. J.; Stephan, M.; Papiol, S.; Zhang, M.; Song, J.; Frommeyer, S. M.; Haupt, H.; Jensen, N.; Kannaiyan, N.; Gupta, R.; Schuler, P.; Pickelmann, P.; McCarthy, M. J.; Schulte, E.; Lande, M.; Falkai, P.; Scheuss, V.; Schulze, T. G.; Zhang, W.
10.1101/2024.07.25.605130 — neuroscience — Posted on 2024-07-25
994 Precious3GPT: Multimodal Multi-Species Multi-Omics Multi-Tissue Transformer for Aging Research and Drug Discovery
Galkin, F.; Naumov, V.; Pushkov, S.; Sidorenko, D.; Urban, A.; Zagirova, D.; Alawi, K. M.; Aliper, A.; Gumerov, R.; Kalashnikov, A.; Mukba, S.; Pogorelskaya, A.; Ren, F.; Shneyderman, A.; Tang, Q.; Xiao, D.; Tyshkovskiy, A.; Ying, K.; Gladyshev, V. N.; Zhavoronkov, A.
10.1101/2024.07.25.605062 — bioinformatics — Posted on 2024-07-25
995 Robustness of time domain near infrared spectroscopy to variations in skin pigmentation
Lacerenza, M.; Amendola, C.; Bargigia, I.; Bossi, A.; Buttafava, M.; Calcaterra, V.; Contini, D.; Damagatla, V.; Negretti, F.; Rossi, V.; Spinelli, L.; Zanelli, S.; Zuccotti, G.; Torricelli, A.
10.1101/2024.07.25.605070 — bioengineering — Posted on 2024-07-25
996 Advancing Liver Gene Therapy: Enhanced Transduction with GalNAc-Bioconjugated rAAV Capsids
Lalys, P. A.; Bourdon, A.; Bouzelha, M.; Alvarez-Dorta, D.; Pavageau, K.; Girard, T.; Peumery, R.; Bouchouireb, Z.; Marchand, M.; Mellet, A.; Ledevin, M.; Depienne, S.; Guilbaud, M.; Croyal, M.; Gouin, S. G.; Roubinet, B.; Landemarre, L.; Adjali, O.; Ayuso, E.; Larcher, T.; Le Guiner, C.; MEVEL, M.; Deniaud, D.
10.1101/2024.07.25.605063 — bioengineering — Posted on 2024-07-25
999 Sex-Specific DNA Methylation and Gene Expression Changes in Mouse Placentas After Early Preimplantation Alcohol Exposure
Legault, L.-M.; Dupas, T.; Breton-Larrivee, M.; Filion-Bienvenue, F.; Lemieux, A.; Langford-Avelar, A.; McGraw, S.
10.1101/2023.09.30.560198 — developmental biology — Posted on 2024-07-25
1000 AP-1 Mediates Cellular Adaptation and Memory Formation During Therapy Resistance
Li, J.; Ravindran, P. T.; O'Farrell, A.; Busch, G. T.; Boe, R. H.; Niu, Z.; Woo, S.; Dunagin, M. C.; Jain, N.; Goyal, Y.; Sarma, K.; Herlyn, M.; Raj, A.
10.1101/2024.07.25.604999 — systems biology — Posted on 2024-07-25
1001 A combination of the geroprotectors trametinib and rapamycin is more effective than either drug alone
Gkioni, L.; Nespital, T.; Monzo, C.; Bali, J.; Nassr, T.; Cremer, A. L.; Beyer, A.; Backes, H.; Gronke, S.; Partridge, L.
10.1101/2024.07.25.605097 — physiology — Posted on 2024-07-25
1002 Single-molecule detection of transient dimerization of opioid receptors 2: Heterodimer blockage reduces morphine tolerance
Zhou, P.; Kasai, R. S.; Fujita, W.; Tsunoyama, T. A.; Ueda, H.; Pigolotti, S.; Fujiwara, T.; Kusumi, A.
10.1101/2024.07.25.605109 — biophysics — Posted on 2024-07-25
1003 Single-molecule detection of transient dimerization of opioid receptors 1: Homodimers' effect on signaling and internalization
Zhou, P.; Tsunoyama, T. A.; Kasai, R. S.; Hirosawa, K. M.; Kalay, Z.; Aladag, A.; Fujiwara, T.; Pigolotti, S.; Kusumi, A.
10.1101/2024.07.25.605080 — biophysics — Posted on 2024-07-25
1004 Diet breadth in two polyphagous Spodoptera moths in a wide range of host and non-host plants and the potential for range expansion
Roy, A.; Waschke, N.; Chattington, S.; Modlinger, R.; Chakraborty, A.; Chirere, T. C.; Larsson, M. C.; Heckel, D. G.; Anderson, P.; Schlyter, F.
10.1101/2024.07.25.605058 — ecology — Posted on 2024-07-25
1006 Co-recognition of histone acetylation and H3K4 trimethylation by GTE4-EML complex in Arabidopsis
Qian, F.; Zhao, Q.-Q.; Zhou, J.-X.; Yuan, D.-Y.; Su, Y.-N.; Li, L.; Chen, S.; He, X.-J.
10.1101/2024.07.25.605061 — molecular biology — Posted on 2024-07-25
1010 Improved tests for the origin of allometric scaling across tree architectures
Chmurzynski, A.; Brummer, A. B.; Savage, V.; Shenkin, A.; Malhi, Y.; Martin-Ducup, O.; Zieminska, K.; Barbier, N.; Enquist, B. J.
10.1101/2024.07.25.605048 — plant biology — Posted on 2024-07-25
1011 Characterization of radiations-inducedgenomic structural variations in Arabidopsis thaliana
Sall, S. O.; Alioua, A.; Staerck, S.; Graindorge, S.; Pellicioli, M.; Schuler, J.; Raffy, Q.; Rousseau, M.; Molinier, J.
10.1101/2024.07.25.605065 — plant biology — Posted on 2024-07-25
1015 Spherical harmonics texture extraction for versatile analysis of biological objects
Gros, O.; Passmore, J. B.; Borst, N.; Kutra, D.; Nijenhuis, W.; Fuqua, T.; Kapitein, L. C.; Crocker, J. M.; Kreshuk, A.; Koehler, S.
10.1101/2024.07.25.605050 — bioinformatics — Posted on 2024-07-25
1017 From egg to adult: a developmental table of the ant Monomorium pharaonis
Rajakumar, A.; Pontieri, L.; Li, R.; Larsen, R. S.; Vasquez-Correa, A.; Frandsen, J. K.; Rafiqi, A. M.; Zhang, G.; Abouheif, E.
10.1101/2020.12.22.423970 — developmental biology — Posted on 2024-07-25
1018 Extravascular spaces are the primary reservoir of antigenic diversity in Trypanosoma brucei infection
Beaver, A.; Keneskhanova, Z.; Cosentino, R. O.; Weiss, B. L.; Awuoche, E. O.; Smallenberger, G. M.; Buenconsejo, G. Y.; Crilly, N. P.; Smith, J. E.; Hakim, J. M.; Zhang, B.; Bobb, B.; Rijo-Ferreira, F.; Figueiredo, L. M.; Aksoy, S.; Siegel, T. N.; Mugnier, M. R.
10.1101/2022.06.27.497797 — microbiology — Posted on 2024-07-25
1025 A novel method for integrating genomic and Tn-Seq data to identify common in vivo fitness mechanisms across multiple bacterial species
Fouts, D. E.; Clarke, T. H.; Brown, A. N.; Ottosen, E. N.; Holmes, C. L.; Moricz, B. S.; Mason, S.; Sinha, R.; Severin, G. B.; Anderson, M. T.; DiRita, V.; Bachman, M. A.; Mobley, H. L. T.
10.1101/2024.07.24.604993 — bioinformatics — Posted on 2024-07-25
1028 High quality genome assembly and annotation (v1) of the eukaryotic terrestrial microalga Coccomyxa viridis SAG 216-4
Kraege, A.; Chavarro-Carrero, E.; Guiglielmoni, N.; Schnell, E.; Kirangwa, J.; Heilmann-Heimbach, S.; Becker, K.; Kohrer, K.; WGGC Team, ; DeRGA Community, ; Schiffer, P.; Thomma, B. P.; Rovenich, H.
10.1101/2023.07.11.548521 — genomics — Posted on 2024-07-25
1029 Genome-wide profiling of DNA repair proteins identifies higher-order coordination in single cells
de Luca, K. L.; Rullens, P. M.; Karpinska, M. A.; de Vries, S. S.; Gacek-Matthews, A.; Pongor, L. S.; Legube, G.; Jachowicz, J. W.; Oudelaar, A. M.; Kind, J.
10.1101/2023.05.10.540169 — genomics — Posted on 2024-07-25
1033 Sox10 is required for systemic initiation of bone mineralization
Gjorcheska, S.; Paudel, S.; McLeod, S.; Snape, L.; Camargo Sosa, K.; Duan, C.; Kelsh, R.; Barske, L.
10.1101/2024.07.24.604990 — developmental biology — Posted on 2024-07-25
1034 A Viral-Encoded Homologue of IPS-1 Modulates Innate Immune Signaling During KSHV Lytic Replication
Miranda, D.; He, B.; Sanchez, J. C.; Sennatti, A.; Bontemps, J.; Tran, J.; Tang, W. S.; Sanchez, D. J.
10.1101/2024.07.24.604690 — microbiology — Posted on 2024-07-25
1039 SimMS: A GPU-Accelerated Cosine Similarity implementation for Tandem Mass Spectrometry
Onoprishvili, T.; Yuan, J.-H.; Petrov, K.; Ingalalli, V.; Khederlarian, L.; Leuchtenmuller, N.; Chandra, S.; Duarte, A.; Bender, A.; Gloaguen, Y.
10.1101/2024.07.24.605006 — bioinformatics — Posted on 2024-07-25
1041 Identification of the trail-following pheromone receptor in termites
Diallo, S.; Kasparova, K.; Sulc, J.; Johny, J.; Krivanek, J.; Nebesarova, J.; Sillam-Dusses, D.; Kyjakova, P.; Vondrasek, J.; Machara, A.; Luksan, O.; Grosse-Wilde, E.; Hanus, R.
10.1101/2024.07.24.605012 — animal behavior and cognition — Posted on 2024-07-25
1042 Gaze audits food items for bite points during human withdraw-to-eat movements
Whishaw, I. Q.; Kuntz, J. R.; Ryait, H.; Phillip, J.; Kopples, J.; Dudley, J.; Karl, J. M.
10.1101/2024.07.24.604915 — animal behavior and cognition — Posted on 2024-07-25
1043 Long-Range Enhancer Networks Gradually Emerge as Key Regulators During Human Cortical Neurogenesis
Li, C.; Zhu, L.; Su, B.; Jia, L.; Hou, Y.; Cui, Z.; Luo, X.; Duan, J.; Guo, J.; Shi, M.; Chen, H.; Li, T.; Zhang, F.
10.1101/2024.07.24.605026 — genomics — Posted on 2024-07-25
1044 Scalable assessment of genome editing off-targets associated with genetic variants
Lin, J.; Nguyen, M. A.; Lin, L. Y.; Zeng, J.; Verma, A.; Neri, N. R.; da Silva, L. F.; Mucci, A.; Wolfe, S.; Shaw, K. L.; Clement, K.; Brendel, C.; Pinello, L.; Pellin, D.; Bauer, D. E.
10.1101/2024.07.24.605019 — genomics — Posted on 2024-07-25
1046 Ultrastructural diversity of alpha-Synuclein pathology in the post-mortem brain of Parkinson patients: implications for Lewy Body formation
Lewis, A.; van den Heuvel, L.; Di Fabrizio, M.; Burger, D.; Huisman, E.; Bol, J. G.; van de Berg, W. D. J.; Stahlberg, H.
10.1101/2024.07.25.605088 — neuroscience — Posted on 2024-07-25
1047 Melanocortin system activates carotid body arterial chemoreceptors in hypertension
Pauza, A. G.; Thakkar, P.; Shen, X.; Felippe, I. S. A.; Rossmann, K.; Oya, M.; Nakamura, K.; Broichhagen, J.; Hodson, D. J.; Pauza, D. H.; Murphy, D.; Paton, J. F.
10.1101/2024.07.22.604704 — neuroscience — Posted on 2024-07-25
1053 Endoglin regulates the integrity of the bone marrow vasculature
Rodriguez, D.; Jaykar, M.; Watts, D.; Sinha, A.; Gaete, D.; Krueger, A.; Mirtschink, P.; Rauner, M.; Chavakis, T.; Arthur, H. M.; Wielockx, B.
10.1101/2024.07.24.605039 — molecular biology — Posted on 2024-07-25
1054 Postnatal xanthine metabolism regulates cardiac regeneration in mammals
Saito, Y.; Sugiura, Y.; Sakaguchi, A.; Sada, T.; Nishiyama, C.; Maeda, R.; Kaneko, M.; Kiyonari, H.; Kimura, W.
10.1101/2024.07.24.605040 — developmental biology — Posted on 2024-07-25
1056 Destabilisation of bam transcripts terminates the mitotic phase of Drosophila female germline differentiation
Samuels, T. J.; Torley, E. J.; Naden, E. L.; Blair, P. E.; Hernandez Frometa, F. A.; Karam Teixeira, F.
10.1101/2024.07.24.604138 — developmental biology — Posted on 2024-07-25
1057 Structure, interaction, and nervous connectivity of beta cell primary cilia
Müller, A.; Klena, N.; Pang, S.; Garcia, L. E. G.; Topcheva, O.; Aurrecoechea Duran, S.; Sulaymankhil, D.; Seliskar, M.; Mziaut, H.; Schöniger, E.; Friedland, D.; Kipke, N.; Kretschmar, S.; Münster, C.; Weitz, J.; Distler, M.; Kurth, T.; Schmidt, D.; Hess, H. F.; Xu, C. S.; Pigino, G.; Solimena, M.
10.1101/2023.12.01.568979 — cell biology — Posted on 2024-07-25
1058 Effective lowering of α-synuclein expression by targeting G-quadruplex structures within the SNCA gene
Pirota, V.; Rey, F.; Esposito, L.; Fantini, V.; Pandini, C.; Maghraby, E.; Di Gerlando, R.; Doria, F.; Mella, M.; Pansarasa, O.; Gandellini, P.; Freccero, M.; Carelli, S.; Cereda, C.
10.1101/2024.02.09.579657 — molecular biology — Posted on 2024-07-25
1060 Spatiotemporal dispersion of DENV1 genotype V in western Colombia
Rojas-Gallardo, D.; Ferrell, T.; Paula, E.; Lopez, D.; Giraldo, B.; Restrepo-Chica, J.; Jimenez-Posada, E.; Martinez-Gutierrez, M.; Ruiz-Saenz, J.; Key, A.; Shariatzadeh, N.; Khosravi, D.; Martinez, M. A.; Bombin, A.; Waggoner, J. J.; Osorio, J. E.; Neufeldt, C. J.; Collins, M. H.; Cardona-Ospina, J. A.; Piantadosi, A.
10.1101/2024.07.24.605015 — evolutionary biology — Posted on 2024-07-25
1062 Changes in maternal blood and placental lipidomic profile in obesity and gestational diabetes: Evidence for sexual dimorphism
Kadam, L.; Velickovic, M.; Straton, K.; Nicora, C. D.; Kyle, J.; Wang, E.; Monroe, M.; Bramer, L.; Myatt, L.; Burnum-Johnson, K.
10.1101/2024.07.24.605016 — molecular biology — Posted on 2024-07-25
1063 Illuminating microbial mat assembly: Cyanobacteria and Chloroflexota cooperate to structure light-responsive biofilms
Bunbury, F.; Rivas, C.; Calatrava, V.; Malkovskiy, A.; Joubert, L.-M.; Parvate, A.; Evans, J. E.; Grossman, A. R.; Bhaya, D.
10.1101/2024.07.24.605005 — microbiology — Posted on 2024-07-25
1064 Flooding patterns shape microbial community in mangrove sediments
Vazquez-Rosas-Landa, M.; Perez-Ceballos, R.; Zaldivar-Jimenez, A.; Herreira-Pacheco, S. E.; Perez-Gonzalez, L. D.; Prieto-Davo, A.; Celis-Hernandez, O.; Canales-Delgadillo, J. C.
10.1101/2024.07.24.604998 — microbiology — Posted on 2024-07-25
1068 In vivo quantification of anterior and posterior chamber volumes in mice: implications for aqueous humor dynamics
Kim, D.; Fang, R.; Zhang, P.; Sun, C.; Li, G.; Montgomery, C.; John, S. W. M.; Stamer, W. D.; Zhang, H. F.; Ethier, C. R.
10.1101/2024.07.24.604989 — physiology — Posted on 2024-07-25
1076 Structures of transcription-translation coupling complexes at each stage of the translation cycle
Zhang, J.; Lu, G.; Zhou, W.; Yang, M.; Li, L.; Shao, H.; Zhou, X.; Chen, C.; Gao, Y.; Ebright, R. H.; Lin, J.; Wang, C.
10.1101/2024.03.13.584796 — molecular biology — Posted on 2024-07-25
1077 Tumor microenvironments impair T cell receptor affinity and function
Yuan, Z.; O'Melia, M. J.; Li, K.; Lyu, J.; Rosado, A. M.; Watson, V. E.; Ashkezari, A. H. K.; Zhou, F.; Kansal, V.; Kinney, B.; Travaglino, S.; Doudy, L. O.; Noel, R. K.; Lucas, S. N.; Kong, S. L.; Jothikumar, P.; Rohner, N. A.; Manspeaker, M. P.; Francis, D. M.; Bai, K.; Ge, C.; Rushdi, M. N.; Chingozha, L.; Ruiperez-Campillo, S.; Jiang, N.; Lu, H.; Schmitt, N. C.; Thomas, S. N.; Zhu, C.
10.1101/2022.09.11.507496 — immunology — Posted on 2024-07-25
1078 Dynamics of striatal action selection and reinforcement learning
Lindsey, J.; Markowitz, J. E.; Gillis, W. F.; Datta, S. R.; Litwin-Kumar, A.
10.1101/2024.02.14.580408 — neuroscience — Posted on 2024-07-25
1079 Modeling Nitric Oxide Diffusion and Plasticity Modulation in Cerebellar Learning
Trapani, A. M.; Sartori, C. A.; Gambosi, B.; Pedrocchi, A.; Antonietti, A.
10.1101/2024.07.24.604957 — neuroscience — Posted on 2024-07-25
1080 A family of bacterial Josephin-like deubiquitinases with an unusual cleavage mode
Hermanns, T.; Kolek, S.; Uthoff, M.; de Heiden, R. A.; Mulder, M. P. C.; Baumann, U.; Hofmann, K.
10.1101/2024.07.24.604956 — biochemistry — Posted on 2024-07-24
1082 Population genetics meets ecology: a guide to individual-based simulations in continuous landscapes
Chevy, E. T.; Min, J.; Caudill, V.; Champer, S. E.; Haller, B. C.; Rehmann, C. T.; Smith, C. C. R.; Tittes, S.; Messer, P. W.; Kern, A. D.; Ramachandran, S.; Ralph, P. L.
10.1101/2024.07.24.604988 — evolutionary biology — Posted on 2024-07-24
1083 Biomimetic model of corticostriatal micro-assemblies discovers new neural code
Pathak, A.; Brincat, S. L.; Organtzidis, H.; Strey, H. H.; Senneff, S.; Antzoulatos, E. G.; Mujica-Parodi, L. R.; Miller, E. K.; Granger, R.
10.1101/2023.11.06.565902 — neuroscience — Posted on 2024-07-24
1085 TIPE drives a cancer stem-like phenotype by promoting glycolysis via PKM2/HIF-1alpha axis in melanoma
Tian, M.; Yang, L.; Zhao, Z.; Li, J.; Wang, L.; Yin, Q.; Hu, W.; Lou, Y.; Du, J.; Zhao, P.
10.1101/2023.11.14.567124 — cancer biology — Posted on 2024-07-24
1091 Population responses to environmental stochasticity are primarily driven by survival-reproduction trade-offs and mediated by aridity
Santos, G. S.; Yang, X.; Gascoigne, S.; Compagnoni, A.; Dias, A.; Tuljapurkar, S. D.; Kajin, M.; Salguero-Gomez, R.
10.1101/2024.07.24.604949 — ecology — Posted on 2024-07-24
1093 DNA O-MAP uncovers the molecular neighborhoods associated with specific genomic loci
Liu, Y.; McGann, C. D.; Krebs, M.; Perkins, T. A.; Fields, R.; Camplisson, C. K.; Hsu, C.; Avanessian, S.; Tsue, A. F.; Kania, E. E.; Shechner, D. M.; Beliveau, B. J.; Schweppe, D. K.
10.1101/2024.07.24.604987 — systems biology — Posted on 2024-07-24
1094 A rewiring of the earliest immune events leading to T-cell mediated disease following intestinal infection in a PINK1 knock out mouse model of Parkinsons disease
Recinto, S.; Kazanova, A.; Afanasiev, E.; MacDonald, A.; Premachandran, S.; Allot, A.; Bessaiah, H.; Cordeiro, B.; Mukherjee, S.; Pei, J.; McBride, H. M.; Trudeau, L.-E.; Gruenheid, S.; Stratton, J. A.
10.1101/2024.06.18.598931 — immunology — Posted on 2024-07-24
1097 Cisplatin drives mitochondrial dysregulation in sensory hair cells
Lee, D. S.; Schrader, A.; Zou, J.; Ang, W. H.; Warchol, M. E.; Sheets, L.
10.1101/2024.01.29.577846 — neuroscience — Posted on 2024-07-24
1099 MYC and p53 alterations cooperate through VEGF signaling to repress cytotoxic T cell and immunotherapy responses in prostate cancer
Murphy, K. C.; DeMarco, K. D.; Zhou, L.; Lopez-Diaz, Y.; Ho, Y.-j.; Li, J.; Bai, S.; Simin, K.; Zhu, L. J.; Mercurio, A. M.; Ruscetti, M.
10.1101/2024.07.24.604943 — cancer biology — Posted on 2024-07-24
1100 Glioblastoma Neurovascular Progenitor Orchestrates Tumor Cell Type Diversity
Fazzari, E.; Azizad, D. J.; Yu, K.; Ge, W.; Li, M. X.; Nano, P. R.; Kan, R. L.; Tum, H. A.; Tse, C.; Bayley, N. A.; Haka, V.; Cadet, D.; Perryman, T.; Soto, J. A.; Wick, B.; Raleigh, D. R.; Crouch, E. E.; Patel, K. S.; Liau, L. M.; Deneen, B.; Nathanson, D. A.; Bhaduri, A.
10.1101/2024.07.24.604840 — cancer biology — Posted on 2024-07-24
1102 Thioether-functionalized cellulose for the fabrication of oxidation-responsive biomaterial coatings and films
DuBois, E. M.; Herrema, K. E.; Simkulet, M. G.; Hassan, L. F.; O'Connor, P. R.; Sen, R.; O'Shea, T. M.
10.1101/2024.07.24.604973 — bioengineering — Posted on 2024-07-24
1103 Stress relaxation rates of myocardium from failing and non-failing hearts
Gionet-Gonzales, M.; Gathman, G.; Rosas, J.; Kunisaki, K. Y.; Inocencio, D. G. P.; Hakami, N.; Milburn, G. N.; Pitenis, A. A.; Campbell, K. S.; Pruitt, B. L.; Stowers, R. S.
10.1101/2024.07.24.604845 — bioengineering — Posted on 2024-07-24
1104 Structures of the multi-domain oxygen sensor DosP: remote control of a c-di-GMP phosphodiesterase by a regulatory PAS domain
Wu, W.; Kumar, P.; Brautigam, C. A.; Cho, S.-C.; Baniasadi, H. R.; Kober, D. L.; Gilles-Gonzales, M.-A.
10.1101/2024.07.24.604967 — biochemistry — Posted on 2024-07-24
1105 Boosting the Predictive Power of Protein Representations with a Corpus of Text Annotations
Duan, H.; Skreta, M.; Cotta, L.; Rajaonson, E. M.; Dhawan, N.; Aspuru-Guzik, A.; Maddison, C. J.
10.1101/2024.07.22.604688 — biochemistry — Posted on 2024-07-24
1106 Similar Won't Make It: Coexistence, Habitat Availability and Suboptimal Restoration
Maresca, F.; Borthagaray, A. I.; Cunillera-Montcusi, D.; Soutullo, A.; Arim, M.
10.1101/2024.07.24.604984 — ecology — Posted on 2024-07-24
1107 Multiscale mechanics drive functional maturation of the vertebrate heart
Andrews, T. G.; Cornwall Scoones, J.; Ramel, M.-C.; Gupta, K.; Briscoe, J.; Priya, R.
10.1101/2024.07.24.604962 — developmental biology — Posted on 2024-07-24
1108 Sox10 is required for systemic initiation of bone mineralization
Barske, L.; Gjorcheska, S.; Paudel, S.; McLeod, S.; Snape, L.; Camargo Sosa, K.; Duan, C.; Kelsh, R.
10.1101/2024.07.24.604990 — developmental biology — Posted on 2024-07-24
1110 Satellite stem cell dysfunction in Duchenne muscular dystrophy
Granet, J. A.; Robertson, R.; Filippelli, R. L.; Cusmano, A.; Li, S.; Yaqubi, M.; Stratton, J. A.; Chang, N. C.
10.1101/2024.07.24.604963 — cell biology — Posted on 2024-07-24
1111 Host-derived CEACAM-laden vesicles engage enterotoxigenic E. coli for elimination and toxin neutralization.
Sheikh, A.; Ganguli, D.; Vickers, T. J.; Singer, B.; Foulke-Abel, J.; Akhtar, M.; Khatoon, N.; Setu, B.; Basu, S.; Maier, N.; Beatty, W.; Chakraborty, S.; Bhuiyan, T. R.; Qadri, F.; Donowitz, M.; Fleckenstein, J. M.
10.1101/2024.07.24.604983 — microbiology — Posted on 2024-07-24
1112 Multi-omics analysis of a traditional fermented food reveals a byproduct-associated subpopulation of Neurospora intermedia for waste-to-food upcycling
Maini Rekdal, V.; Villalobos-Escobedo, J. M.; Rodriguez-Valeron, N.; Olaizola Garcia, M.; Prado Vasquez, D.; Rosales, A.; Sorensen, P. M.; Baidoo, E. E. K.; Calheiros de Carvalho, A.; Riley, R.; Lipzen, A.; He, G.; Yan, M.; Haridas, S.; Daum, C.; Yoshinaga, Y.; Ng, V.; . Grigoriev, I. V.; Munk, R.; Wijaya, C. H. H.; Nuraida, L.; Damayanti, I.; Keasling, J. D.
10.1101/2024.07.24.604980 — microbiology — Posted on 2024-07-24
1113 Satellite glial contact enhances differentiation and maturation of human induced sensory neurons
LeBlang, C. J.; Pazyra-Murphy, M. F.; Silagi, E.; Dasgupta, S.; Tsolias, M.; Miller, T.; Petrova, V.; Zhen, S.; Gerrish, K.; Jovanovic, V.; Castellano, D.; Ormanoglu, P.; Tristan, C.; Woolf, C. J.; Tasdemir-Yilmaz, O.; Segal, R. A.
10.1101/2024.07.24.604966 — neuroscience — Posted on 2024-07-24
1115 Patient-specific responses to SMN2 splice-modifying treatments in spinal muscular atrophy fibroblasts
Signoria, I.; Zwartkruis, M. M.; Geerlofs, L.; Perenthaler, E.; Faller, K. M.; James, R.; McHale-Owen, H.; Green, J. W.; Kortooms, J. V.; Snellen, S. H.; Asselman, F.-L.; Gillingwater, T. H.; Viero, G.; Wadman, R. I.; van der Pol, W. L.; Groen, E. J.
10.1101/2024.07.24.604892 — molecular biology — Posted on 2024-07-24
1119 First-Year Dynamics of the Anaerobic Microbiome and Archaeome in Infants Oral and Gastrointestinal Systems
Neumann, C. J.; Mohammadzadeh, R.; Woh, P. Y.; Kobal, T.; Pausan, M.-R.; Shinde, T.; Haid, V.; Mertelj, P.; Mahnert, A.; Kumpitsch, C.; Jantscher-Krenn, E.; Moissl-Eichinger, C.
10.1101/2024.07.24.604926 — microbiology — Posted on 2024-07-24
1120 High fat low carbohydrate diet is linked to protection against CNS autoimmunity
Ni, D.; Tan, J.; Reyes, J.; Senior, A.; Andrews, C.; Taitz, J.; Potier, C.; Wishart, C.; Spiteri, A. G.; Piccio, L.; King, N. J. C.; Barres, R.; Raubenheimer, D.; Simpson, S.; Nanan, R.; Macia, L.
10.1101/2024.07.23.604865 — immunology — Posted on 2024-07-24
1121 Aberration correction in long GRIN lens-based microendoscopes for extended field-of-view two-photon imaging in deep brain regions
Sattin, A.; Nardin, C.; Daste, S.; Moroni, M.; Reddy, I.; Liberale, C.; Panzeri, S.; Fleischmann, A.; Fellin, T.
10.1101/2024.07.24.604890 — neuroscience — Posted on 2024-07-24
1123 MultiOmicsAgent: Guided extreme gradient-boosted decision trees-based approaches for biomarker-candidate discovery in multi-omics data
Settelmeier, J.; Goetze, S.; Boshart, J.; Fu, J.; Steiner, S. N.; Gesell, M.; Schueffler, P. J.; Salimova, D.; Pedrioli, P. G. A.; Wollscheid, B.
10.1101/2024.07.24.604727 — bioinformatics — Posted on 2024-07-24
1128 CIB2 as a Ca2+ Sensor for Auditory Mechano-Electrical Transduction and Linked to Genetic-Heterogeneity of TMC1 in Hearing Loss
Wu, S.; Lin, L.; Hu, Q.; Yao, X.; Wang, H.; Liu, S.; Liu, Q.; Lu, L.; Xi, Y.; Lin, Y.; Gong, J.; Hu, R.; Zhan, W.; Luo, Y.; He, G.; Liu, Z.; Xiong, W.; Wang, Q.; Xu, Z.; Bai, F.; Lu, Q.
10.1101/2024.07.24.604958 — molecular biology — Posted on 2024-07-24
1129 Detection and decontamination of chronic wasting disease prions during venison processing
Milstein, M. S.; Gresch, S. C.; Schwabenlander, M.; Li, M.; Bartz, J.; Bryant, D.; Christenson, P.; Lindsey, L.; Lurndahl, N.; Oh, S.-H.; Rowden, G.; Shoemaker, R.; Wolf, T. M.; Larsen, P. A.; Lichtenberg, S. S.
10.1101/2024.07.23.604851 — microbiology — Posted on 2024-07-24
1130 HLA topography enforces shared and convergent immunodominant B cell and antibody alloresponses in transplant recipients
Killian, J. T.; King, R. G.; Lucander, A. C.; Kizziah, J. L.; Fucile, C. F.; Diaz-Avalos, R.; Qiu, S.; Silva-Sanchez, A.; Mousseau, B. J.; Macon, K. J.; Callahan, A. R.; Yang, G.; Hossain, M. E.; Akther, J.; Houp, J. A.; Rosenblum, F. D.; Porrett, P. M.; Ong, S. C.; Kumar, V.; Saphire, E. O.; Kearney, J. F.; Randall, T. D.; Rosenberg, A. F.; Green, T. J.; Lund, F. E.
10.1101/2023.03.31.534734 — immunology — Posted on 2024-07-24
1131 Somatic hypermutation-mediated paratope flexibility improves the cross-reactivity of human malaria antibodies
Murugan, R.; Hanke, A.; Oludada, O. E.; Costa, G.; Flores-Garcia, Y.; Mustafa, G.; Li, K.; Huntwork, R. H. C.; Horn, G.; Sekaran, M.; Tomaras, G.; Zavala, F.; Levashina, E. A.; Ketchem, R. R.; Wade, R. C.; Wardemann, H.
10.1101/2024.07.24.604858 — immunology — Posted on 2024-07-24
1132 Presymptomatic Targeted Circuit Manipulation for Ameliorating Huntington's Disease Pathogenesis
Ikefuama, E. C.; Slaviero, A. N.; Schalau, R. C.; Gott, M. L.; Tree, M. O.; Dunbar, G. L.; Rossignol, J.; Hochgeschwender, U.
10.1101/2024.07.24.604946 — neuroscience — Posted on 2024-07-24
1133 CD2AP is Co-Expressed with Tropomyosin-Related Kinase A and Ras-Related Protein Rab-5A in Cholinergic Neurons of the Murine Basal Forebrain
Fitzsimons, L. A.; Atif-Sheikh, M.; Lovely, J.; Mueth, M.; Rice, M.; Kotredes, K. P. A.; Howell, G.; Harrison, B. J.
10.1101/2024.07.24.604961 — neuroscience — Posted on 2024-07-24
1135 Epigenetic control of metabolic identity across cell types
Pacheco, M. P.; Gerard, D.; Mangan, R. J.; Chapman, A. R.; Hecker, D.; Kellis, M.; Schulz, M. H.; Sinkkonen, L.; Sauter, T.
10.1101/2024.07.24.604914 — systems biology — Posted on 2024-07-24
1137 Rice JASMONIC ACID OXIDASES (OsJAO) control resting jasmonate metabolism to promote development and repress basal immune responses
Ndecky, S. Y.; Malherbe, L.; Villette, C.; Chalvon, V.; Meusnier, I.; Beltran-Valencia, D.; Baumberger, N.; Riemann, M.; Kroj, T.; Champion, A.; Heitz, T.
10.1101/2024.07.24.604933 — plant biology — Posted on 2024-07-24
1138 Discovery and evaluation of novel biomarkers reveal dasatinib as a potential treatment for a specific subtype of Triple-Negative Breast Cancer
Ortega-Alvarez, D.; Tebar-Garcia, D.; Casado-Pelaez, M.; Castillo-Agea, E.; Balibrea-Rull, J.; Olivares-Osuna, D.; Perez-Parra, D.; Guardia, C.; Musulen, E.; Vinuesa-Pitarch, E.; Sanchez-Lopez, E.; Postigo-Corrales, F.; Ballana, E.; Martinez-Cardus, A.; Margeli, M.; Esteller, M.; Fernandez-Ruiz, P. L.; Luengo-Gil, G.; Mereu, E.; Galan-Moya, E. M.; Rodilla, V.
10.1101/2024.07.24.603752 — cancer biology — Posted on 2024-07-24
1140 Size control and oscillations of active droplets in synthetic cells
Sastre, J.; Thatte, A. A.; Bergmann, A. M.; Stasi, M.; Tena-Solsona, M.; Weber, C. A.; Boekhoven, J.
10.1101/2024.07.24.604607 — biophysics — Posted on 2024-07-24
1143 Prediction of Hemolytic Peptides and their Hemolytic Concentration (HC50)
Rathore, A. S.; Kumar, N.; Choudhury, S.; Mehta, N. K.; Raghava, G. P. S.
10.1101/2024.07.23.604887 — bioinformatics — Posted on 2024-07-24
1144 Enhancing the Reverse Transcriptase Function in Taq Polymerase via AI-driven Multiparametric Rational Design
Tomilova, Y. E.; Russkikh, N. E.; Yi, I. M.; Shaburova, E. V.; Tomilov, V. N.; Pyrinova, G. B.; Brezhneva, S. O.; Tikhonyuk, O. S.; Gololobova, N. S.; Popichenko, D. V.; Arkhipov, M. O.; Bryzgalov, L. O.; Brenner, E. V.; Artyukh, A. A.; Shtokalo, D. N.; Antonets, D. V.; Ivanov, M. K.
10.1101/2024.07.24.604875 — bioengineering — Posted on 2024-07-24
1145 Broad substrate scope C-C oxidation in cyclodipeptides catalysed by a flavin-dependent filament
Sutherland, E.; Harding, C. J.; Monceau De Bergendal, T. M. Y. D.; Florence, G. J.; Ackermann, K.; Bode, B. E.; Synowksy, S.; Sundaramoorthy, R.; Czekster, C. M.
10.1101/2024.07.24.604905 — biochemistry — Posted on 2024-07-24
1149 Phylotranscriptomics reveals convergent behavioral evolution associated with shared and unique mechanisms in cavity-nesting songbirds
Lipshutz, S. E.; Hibbins, M. S.; Bentz, A. B.; Buechlin, A. M.; Empson, T. A.; George, E. M.; Hauber, M. E.; Rusch, D. B.; Schelsky, W. M.; Thomas, Q. K.; Torneo, S. J.; Turner, A. M.; Wolf, S. E.; Woodruff, M. J.; Hahn, M. W.; Rosvall, K. A.
10.1101/2024.02.13.580205 — evolutionary biology — Posted on 2024-07-24
1150 Desmodium Volatiles in "Push-Pull' Agriculture and Protection Against the Fall Armyworm, Spodoptera frugiperda
Odermatt, D. M.; Chidawanyika, F.; Mutyambai, D. M.; Schmid, B.; Domeignoz Horta, L. A.; Tamiru, A.; Schuman, M. C.
10.1101/2024.07.24.604900 — ecology — Posted on 2024-07-24
1153 ER-mitochondria distance is a critical parameter for efficient mitochondrial Ca2+ uptake and oxidative metabolism.
Dematteis, G.; Tapella, L.; Casali, C.; Talmon, M.; Tonelli, E.; Reano, S.; Ariotti, A.; Pessolano, E.; Malecka, M.; Chrostek, G.; Kilkoviene, G.; Umbrasas, D.; Distasi, C.; Grilli, M.; Ladds, G.; Filigheddu, N.; Fresu, L. G.; Mikoshiba, K.; Matute, C.; Ramos-Gonzalez, P.; Jekabsone, A.; Cali, T.; Brini, M.; Biggiogera, M.; Cavaliere, F.; Miggiano, R.; Genazzani, A. A.; Lim, D.
10.1101/2024.07.24.604907 — cell biology — Posted on 2024-07-24
1155 TORC1-dependent control of fission yeast cohesin
Besson, D.; Vaur, S.; Vazquez, S.; TOURNIER, S.; Gachet, Y.; Birot, A.; Claverol, S.; Marston, A.; Damdimopoulos, A.; Ekwall, K.; Javerzat, J.-P.
10.1101/2024.07.24.603895 — molecular biology — Posted on 2024-07-24
1157 Microscale Spatial Dysbiosis in Oral biofilms Associated with Disease
Grodner, B.; Wu, D. T.; Hahm, S.; Takayasu, L.; Wen, N.; Kim, D. M.; Chen, C.-Y.; De Vlaminck, I.
10.1101/2024.07.24.604873 — microbiology — Posted on 2024-07-24
1161 Nuclear FAK aggravates CD8+ T cell exhaustion via the SP1-IL-6 axis in colorectal cancer
Kong, H.; Wu, X.; Yang, Q.; Wu, C.; Yu, X.; Yang, J.; Xie, D.; Dai, Y.; Chen, L.; Ma, P.; Dai, S.; Huang, L.; Chen, C.; Mi, P.; Peng, Y.; Shi, H.; Zhang, D.; Ke, N.; Hu, B.; Zhou, Z.; Cao, D.; Wang, P.; Chen, L.; Liu, Y.-H.; Jiang, H.
10.1101/2024.07.24.604770 — immunology — Posted on 2024-07-24
1162 Supervised Automation of Cell Counting in Confocal Microscopic Cochlear Imaging Datasets Using Macro in Imaris
Rahman, M. T.; Khan, N. A.; Mokbul, M. I.; Razu, I.; Fatima, S. M.; Lira, S. S.; Garcia, C.; Eckard, P.; Hansen, M. R.
10.1101/2024.07.24.604970 — immunology — Posted on 2024-07-24
1163 Different Roles of D1/D2 Medium Spiny Neurons in the Nucleus Accumbens in Pair Bond Formation of Male Mandarin Voles
Zhang, L.; Qu, Y.; Young, L. J.; Hou, W.; Liu, L.; Liu, J.; Wang, Y.; Li, L.; Guo, X.; Li, Y.; Huang, C.; Lv, Z.; Li, Y.-T.; Jia, R.; Lian, T.; He, Z.; Tai, F.-D.
10.1101/2024.07.24.604911 — neuroscience — Posted on 2024-07-24
1165 Longevity or Well-being? A Dual-Dimension Structure of Neuroticism
He, Y.; Xiao, J.; Hu, K.; Gao, T.; Yan, Y.; Wang, L.; Li, K.; Lei, W.; Zhao, K.; Dong, C.; Tian, X.; Ding, C.; Peng, Y.; Xian, J.; Huang, S.; Liu, X.; Li, L.; Zhang, P.; Zhang, Z.; He, S.; Li, A.; Liu, B.
10.1101/2024.07.23.604876 — neuroscience — Posted on 2024-07-24
1167 Neuron-specific partial reprogramming in the dentate gyrus impacts mouse behavior and ameliorates age-related decline in memory and learning.
Vilchez-Acosta, A.; Maza, M. d. C.; Parras, A.; Planells, A.; Pico, S.; Desdin-Mico, G.; Mrabti, C.; Branchina, C.; Yacoub Maroun, C.; Deigin, Y.; Ocampo, A.
10.1101/2024.07.24.604939 — neuroscience — Posted on 2024-07-24
1168 Investigation of a Novel Mouse Model of Prader-Willi Syndrome with Invalidation of Necdin and Magel2
Barelle, P.-Y.; Sicardi, A.; Schaller, F.; Buron, J.; Becquet, D.; Omnes, F.; Watrin, F.; Santos, C.; Menuet, C.; Francois-Bellan, A.-M.; Caron, E.; Klucznik, J.; Prevot, V.; Bouret, S. G.; Muscatelli, F.
10.1101/2024.07.24.604909 — systems biology — Posted on 2024-07-24
1169 An Organism-Level Quantitative Flux Model of Energy Metabolism in Mice
Yuan, B.; Doxsey, W.; Tok, O.; Kwon, Y. Y.; Inouye, K. E.; Hotamisligil, G.; Hui, S.
10.1101/2024.02.11.579776 — systems biology — Posted on 2024-07-24
1172 Haptoglobin and glutamine synthetase may biomark cachexia induced by anti-acute myeloid leukemia chemotherapy
Campelj, D. G.; Timpani, C. A.; Spiesberger, G.; Formosa, L. E.; Steele, J.; Zhang, H.; Schittenhelm, R. B.; Leow, L.; Goodman, C.; Rybalka, E.
10.1101/2024.07.24.604689 — physiology — Posted on 2024-07-24
1173 Loss of H3K9 trimethylation leads to premature aging
Mrabti, C.; Yang, N.; Desdin-Mico, G.; Alonso-Calleja, A.; Vilchez-Acosta, A.; Pico, S.; Parras, A.; Piao, Y.; Schoenfeldt, L.; Luo, S.; Haghani, A.; Brooke, R.; Maza, M. d. C.; Branchina, C.; Yacoub Maroun, C.; von Meyenn, F.; Naveiras, O.; Horvath, S.; Sen, P.; Ocampo, A.
10.1101/2024.07.24.604929 — physiology — Posted on 2024-07-24
1174 Compromised chronic efficacy of a Glucokinase Activator AZD1656 in mouse models for common human GCKR variants
Ford, B. E.; Chachra, S. S.; Alshawi, A.; Oakley, F.; Fairclough, R. J.; Smith, D. M.; Tiniakos, D.; Agius, L.
10.1101/2024.07.24.604910 — pharmacology and toxicology — Posted on 2024-07-24
1175 CRISPR-inhibition screen for lncRNAs linked to melanoma growth and metastasis
Petroulia, S.; Hockemeyer, K.; Tiwari, S.; Berico, P.; Shamloo, S.; Banijamali, S. E.; Vega-Saenz de Miera, E.; Gong, Y.; Thandapani, P.; Wang, E.; Schulz, M.; Tsirigos, A.; Osman, I.; Aifantis, I.; Imig, J.
10.1101/2024.07.24.604899 — cancer biology — Posted on 2024-07-24
1177 Probing the modulation of enzyme kinetics by multi-temperature, time-resolved serial crystallography
Schulz, E. C.; Prester, A.; von Stetten, D.; Gore, G.; Hatton, C. E.; Bartels, K.; Leimkohl, J.-P.; Schikora, H.; Ginn, H. M.; Tellkamp, F.; Mehrabi, P.
10.1101/2021.11.07.467596 — biophysics — Posted on 2024-07-24
1178 Energetic portrait of the amyloid beta nucleation transition state
Arutyunyan, A.; Seuma, M.; Faure, A. J.; Bolognesi, B.; Lehner, B.
10.1101/2024.07.24.604935 — biophysics — Posted on 2024-07-24
1182 PrePR-CT: Predicting Perturbation Responses in Unseen Cell Types Using Cell-Type-Specific Graphs
Alsulami, R.; Lehmann, R.; Khan, S.; Lagani, V.; Gomez-Cabrero, D.; Kiani, N.; Tegner, J.
10.1101/2024.07.24.604816 — bioinformatics — Posted on 2024-07-24
1184 Evolutionary Origins of Self-sustained Kai Protein Circadian Oscillators
Mukaiyama, A.; Furuike, Y.; Ito-Miwa, K.; Onoue, Y.; Horiuchi, K.; Yamashita, E.; Akiyama, S.
10.1101/2024.07.23.604570 — biochemistry — Posted on 2024-07-24
1185 Overcoming the challenges of cascade reactions and complex substrates in natural product biocatalysis: Immobilization of a cyclodipeptide synthase.
Alvarado-Ramirez, L.; Sutherland, E.; Melchor-Martinez, E. M.; Parra-Saldivar, R.; Bonaccorso, A. D.; Czekster, C. M.
10.1101/2024.07.24.604810 — biochemistry — Posted on 2024-07-24
1191 Unraveling the relationship between cancer and life history traits in vertebrates
Bulls, S.; Platner, L.; Ayub, W.; Moreno, N.; Arditi, J.-P.; Dreyer, S.; McCain, S.; Wagner, P.; Burgstaller, S.; Davis, L. R.; Bruins - van Sonsbeek, L. G. R.; Fischer, D.; Lynch, V. J.; Claude, J.; Glaberman, S.; Chiari, Y.
10.1101/2022.07.12.499088 — evolutionary biology — Posted on 2024-07-24
1197 Coxsackievirus B infection invokes unique cell-type specific responses in primary human pancreatic islets
Veronese-Paniagua, D. A.; Hernandez-Rincon, D. C.; Taylor, J. P.; Tse, H. M.; Millman, J. R.
10.1101/2024.07.23.604861 — cell biology — Posted on 2024-07-24
1199 Circadian rhythms of macrophages are altered by the acidic pH of the tumor microenvironment
Knudsen-Clark, A. M.; Mwangi, D.; Cazarin, J.; Morris, K.; Baker, C.; Hablitz, L. M.; McCall, M. N.; Kim, M.; Altman, B. J.
10.1101/2024.02.14.580339 — immunology — Posted on 2024-07-24
1201 3D-Imaging of synapses in neuronal tissues with synchrotron X-ray ptychography
Bosch, C.; Aidukas, T.; Holler, M.; Pacureanu, A.; Mueller, E.; Peddie, C. J.; Zhang, Y.; Cook, P.; Collinson, L.; Bunk, O.; Menzel, A.; Guizar-Sicairos, M.; Aeppli, G.; Diaz, A.; Wanner, A.; Schaefer, A.
10.1101/2023.11.16.567403 — neuroscience — Posted on 2024-07-24
1202 Poly ADP-Ribose Signaling is Dysregulated in Huntington Disease Patients
Maiuri, T.; Bazan, C. B.; Harding, R. J.; Begeja, N.; Kam, T.-I.; Byrne, L. M.; Rodrigues, F. B.; Warner, M. M.; Neuman, K.; Mansoor, M.; Badiee, M.; Dasovich, M.; Wang, K.; Thompson, L. M.; Leung, A. K.; Andres, S. N.; Wild, E. J.; Dawson, T. M.; Dawson, V. L.; Arrowsmith, C. H.; Truant, R.
10.1101/2022.11.23.517669 — neuroscience — Posted on 2024-07-24
1205 A comprehensive chemotyping and gonadal regulation of seven kisspeptinergic neuronal populations in the mouse brain
Hernandez, V. S.; Zetter, M. A.; Hernandez-Perez, O. R.; Hernandez-Gonzalez, R.; Camacho-Arroyo, I. S.; Millar, R. P.; Eiden, L. E.; Zhang, L.
10.1101/2024.07.23.604881 — neuroscience — Posted on 2024-07-24
1206 Omics driven onboarding of the carotenoid producing red yeast Xanthophyllomyces dendrorhous CBS 6938
Tobin, E. E.; Collins, J. H.; Marsan, C. B.; Nadeau, G. T.; Mori, K.; Lipzen, A.; Mondo, S.; Grigoriev, I. V.; Young, E. M.
10.1101/2023.07.31.551333 — synthetic biology — Posted on 2024-07-24
1208 Resolving the three-dimensional interactome of Human Accelerated Regions during human and chimpanzee neurodevelopment
Pal, A.; Noble, M. A.; Morales, M.; Pal, R.; Baumgartner, M.; Yang, J. W.; Yim, K. M.; Uebbing, S.; Noonan, J. P.
10.1101/2024.06.25.600691 — genomics — Posted on 2024-07-24
1209 Host trees partially explain the complex bacterial communities of two threatened saproxylic beetles
Kolasa, ; Krovi, R. S.; Plewa, ; Jaworski, ; Kadej, ; Smolis, ; Gutowski, ; Sucko, ; Ruta, ; Olbrycht, ; Saluk, ; Oczkowicz, ; Kajtoch,
10.1101/2024.07.24.604729 — genetics — Posted on 2024-07-24
1213 Preclinical evaluation of tissue-selective gene therapies for congenital generalised lipodystrophy
Tiwari, M.; Roumane, A.; Sommer, N.; Han, W. D.; Delibegovic, M.; Rochford, J.; Mcilroy, G. D.
10.1101/2024.06.27.600757 — molecular biology — Posted on 2024-07-24
1214 Dissecting the dynamics of coordinated active transcriptional repression in a multicellular organism
Pimmett, V. L.; Douaihy, M.; Maillard, L.; Trullo, A.; Dufourt, J.; Lenden-Hasse, H.; Radulescu, O.; Lagha, M.
10.1101/2024.02.05.577724 — molecular biology — Posted on 2024-07-24
1215 Mutational landscape and molecular bases of echinocandin resistance
Durand, R.; Torbey, A. G.; Giguere, M.; Pageau, A.; Dube, A. K.; Lagüe, P.; Landry, C. R.
10.1101/2024.07.21.604487 — molecular biology — Posted on 2024-07-24
1216 Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis dependent functional plasticity.
Cox, D. J.; Connolly, S. A.; Maoldomhnaigh, C. O.; Brugman, A. A.; Thomas, O. S.; Duffin, E.; Gogan, K. M.; O Gallchobhair, O.; Murphy, D. M.; O'Rourke, S. A.; O'Connell, F.; Nadarajan, P.; Phelan, J. J.; Gleeson, L. E.; Basdeo, S. A.; Keane, J.
10.1101/2024.03.20.585747 — immunology — Posted on 2024-07-24
1220 Anthropogenic climate change will likely outpace coral range expansion
Vogt-Vincent, N. S.; Pringle, J. M.; Cornwall, C. E.; McManus, L. C.
10.1101/2024.07.23.604846 — ecology — Posted on 2024-07-24
1221 Cell-Surface RNA Associates with Heparan Sulfate and RNA-Binding Proteins to Modulate Receptor-Ligand Interactions
Li, Z.; Joshi, B. S.; Wijdeven, R. H.; Santos-Barriopedro, I.; Shademan, M.; Bos, E.; Tanenbaum, M.; Boons, G.-J.; Sharp, T.; Vermeulen, M.; Raz, V.; Joo, C.
10.1101/2024.07.23.604836 — molecular biology — Posted on 2024-07-24
1222 A nuclear RNA degradation code for eukaryotic transcriptome surveillance
Soles, L. V.; Liu, L.; Zou, X.; Yoon, Y.; Li, S.; Tian, L.; Valdez, M.; Yu, A.; Yin, H.; Li, W.; Ding, F.; Seelig, G.; Li, L.; Shi, Y.
10.1101/2024.07.23.604837 — molecular biology — Posted on 2024-07-24
1223 Activating FcγRs on monocytes are necessary for optimal Mayaro virus clearance
Dunagan, M. M.; Dabilla, N.; McNinch, C.; Brenchley, J. M.; Dolan, P. T.; Fox, J. M.
10.1101/2024.07.23.604823 — immunology — Posted on 2024-07-24
1226 Genetic Architecture and Analysis Practices of Circulating Metabolites in the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program
Wang, N.; Ockerman, F. P.; Zhou, L. Y.; Grove, M. L.; Alkis, T.; Barnard, J.; Bowler, R. P.; Clish, C. B.; Chung, S.; Drzymalla, E.; Evans, A. M.; Franceschini, N.; Gerszten, R. E.; Gillman, M. G.; Hutton, S. R.; Kelly, R. S.; Kooperberg, C.; Larson, M. G.; Lasky-Su, J. A.; Meyers, D. A.; Woodruff, P. G.; Reiner, A. P.; Rich, S. S.; Rotter, J.; Silverman, E. K.; Ramachandran, V. S.; Weiss, S. T.; Wong, K. E.; Wood, A. C.; Wu, L.; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, ; Yarden, R.; Blackwell, T.; Smith, A. V.; Chen, H.; Raffield, L. M.; Yu, B.
10.1101/2024.07.23.604849 — bioinformatics — Posted on 2024-07-24
1228 Mechanism-guided engineering of a minimal biological particle for genome editing
Ngo, W.; Peukes, J. T.; Baldwin, A.; Xue, Z. W.; Hwang, S.; Stickels, R. R.; Lin, Z.; Satpathy, A.; Wells, J. A.; Schekman, R.; Nogales, E.; Doudna, J. A.
10.1101/2024.07.23.604809 — bioengineering — Posted on 2024-07-24
1229 Sequencing 1206 genomes reveals origin and movement of Aedes aegypti driving increased dengue risk
Crawford, J. E.; Balcazar, D.; Redmond, S.; Rose, N. H.; Youd, H. A.; Lucas, E. R.; Sudirman Made Ali, R.; Al-Nazawi, A. M.; Badolo, A.; CHEN, C.-H.; Cosme, L. V.; Henke, J. A.; Hung, K. Y.; Kluh, S.; Liu, W. -L.; Maringer, K.; Micieli, M. V.; Pless, E.; Sombie, A. R.; Surendran, S. N.; Wahid, I.; Armbruster, P. A.; Weetman, D.; McBride, C. S.; Gloria-Soria, A.; Powell, J. R.; White, B. J.
10.1101/2024.07.23.604830 — genomics — Posted on 2024-07-24
1230 Genetic evolution of keratinocytes to cutaneous squamous cell carcinoma
Tandukar, B.; Deivendran, D.; Chen, L.; Cruz-Pacheco, N.; Sharma, H.; Xu, A.; Bandari, A. K.; Chen, D.; George, C.; Marty, A.; Cho, R. J.; Cheng, J.; Saylor, D.; Gerami, P.; Arron, S. T.; Bastian, B. C.; Shain, A. H.
10.1101/2024.07.23.604673 — genomics — Posted on 2024-07-24
1233 The battle of the sexes in humans is highly polygenic
Cole, J. M.; Scott, C. B.; Johnson, M. M.; Golightly, P. R.; Carlson, J.; Ming, M. J.; Harpak, A.; Kirkpatrick, M.
10.1101/2024.07.23.604850 — evolutionary biology — Posted on 2024-07-24
1235 Astrogliosis And Neuroinflammation Underlie Scoliosis Upon Cilia Dysfunction
Djebar, M.; Anselme, I.; Pezeron, G.; Bardet, P.-L.; Cantaut-Belarif, Y.; Eschstruth, A.; Lopez-Santos, D.; Le Ribeuz, H.; Jenett, A.; Khoury, H.; Veziers, J.; Parmentier, C.; Hirschler, A.; Carapito, C.; Bachmann-Gagescu, R.; Schneider-Maunoury, S.; Vesque, C.
10.1101/2024.02.22.581530 — developmental biology — Posted on 2024-07-24
1236 Comparative analysis of 43 distinct RNA modifications by nanopore tRNA sequencing
White, L. K.; Dobson, K.; del Pozo, S.; Bilodeaux, J. M.; Andersen, S. E.; Baldwin, A.; Barrington, C.; Koertel, N.; Martinez-Seidel, F.; Strugar, S. M.; Watt, K. E. N.; Mukherjee, N.; Hesselberth, J. R.
10.1101/2024.07.23.604651 — molecular biology — Posted on 2024-07-24
1238 A single-cell atlas of the Culex tarsalis midgut during West Nile virus infection
Fitzmeyer, E. A.; Dutt, T. S.; Pinaud, S.; Graham, B.; Gallichotte, E. N.; Hill, J. L.; Campbell, C.; Ogg, H.; Howick, V. M.; Lawniczak, M.; Osborne Nishimura, E.; Merkling, S. H.; Henao-Tamayo, M.; Ebel, G. D.
10.1101/2024.07.23.603613 — microbiology — Posted on 2024-07-24
1239 Mechanisms of Anammox Adaptation to High Temperatures: Increased Cyclization of Ladderane Lipids and Proteomic Insights
Karmann, C.; Navratilova, K.; Behner, A.; Noor, T.; Danner, S.; Santrucek, J.; Podzimek, T.; Lopez Marin, M. A.; Hajslova, J.; Bartacek, J.; Lipovova, P.; Kouba, V.
10.1101/2024.07.23.604647 — microbiology — Posted on 2024-07-24
1242 Lack of Single Amino Acids Transcriptionally Remodels Sensory Systems to Enhance the Intake of Protein and Microbiota
Ezra, G.; Henriques, S. F.; Munch, D.; Francisco, A. P.; Baltazar, C.; Elias, A. P.; Deplancke, B.; Ribeiro, C.
10.1101/2024.07.23.604616 — neuroscience — Posted on 2024-07-24
1243 Distinct subcircuits within the mesolimbic dopamine system encode the salience and valence of social stimuli
Cross, E. A.; Borland, J. M.; Shaughnessy, E. K.; Lee, S. D.; Vu, V.; Sambor, E. A.; Huhman, K. L.; Albers, H. E.
10.1101/2024.07.23.604824 — neuroscience — Posted on 2024-07-24
1245 Impaired experience-dependent inter-areal network connectivity across the visual cortex in Fmr1 KO mice
Cheng, X.; Nareddula, S.; Gao, H.-C.; Chen, Y.; Xiao, T.; Nadew, Y. Y.; Xu, F.; Edens, P. A.; Quinn, C. J.; Huang, F.; Kimbrough, A.; Chubykin, A. A.
10.1101/2024.07.23.601989 — neuroscience — Posted on 2024-07-24
1251 Beware of Data Leakage from Protein LLM Pretraining
Hermann, L.; Fiedler, T.; Nguyen, H. A.; Nowicka, M.; Bartoszewicz, J. M.
10.1101/2024.07.23.604678 — bioinformatics — Posted on 2024-07-24
1253 In vivo-Active Soluble Epoxide Hydrolase-targeting PROTACs with Improved Potency and Stability
Nakane, K.; Morisseau, C.; Dowker-Key, P. D.; Benitez, G.; Aguilan, J. T.; Nagai, E.; Sidoli, S.; Hammock, B. D.; Bettaieb, A.; Shinoda, K.; Kitamura, S.
10.1101/2024.07.23.604814 — biochemistry — Posted on 2024-07-24
1256 Site-specific metabolic labeling reveals proteome-wide phospho-dynamics
Alevra, M.; Correa Marrero, M.; Kluever, V.; Mandad, S.; Hemandhar-Kumar, N.; Pan, K.-T.; van Gerwen, J.; Glowacki, S. K.; Wildhagen, H.; Ischebeck, T.; Liu, Y.; RIzzoli, S. O.; Urlaub, H.; Beltrao, P.; Fornasiero, E. F.
10.1101/2024.07.23.604744 — molecular biology — Posted on 2024-07-24
1259 Assessing the balance between excitation and inhibition in chronic pain through the aperiodic component of EEG
Gil Avila, C.; May, E. S.; Bott, F. S.; Tiemann, L.; Hohn, V.; Heitmann, H.; Zebhauser, P. T.; Gross, J.; Ploner, M.
10.1101/2024.07.23.604775 — neuroscience — Posted on 2024-07-24
1261 Resolving artefacts in voltage-clamp experiments with computational modelling: an application to fast sodium current recordings
Lei, C. L.; Clark, A. P.; Clerx, M.; Wei, S.; Bloothooft, M.; de Boer, T. P.; Christini, D. J.; Krogh-Madsen, T.; Mirams, G. R.
10.1101/2024.07.23.604780 — systems biology — Posted on 2024-07-24
1264 A common CTRB misfolding variant associated with pancreatic cancer risk causes ER stress and inflammation in mice
Bodas, C.; Felipe, I.; Chanez, B.; Lafarga, M.; Lopez-de-Maturana, E.; Martinez-de-Villarreal, J.; del Pozo, N.; Malumbres, M.; Vargiu, P.; Cayuela-Lopez, A.; Peset, I.; Connelly, K. E.; Hoskins, J.; Mendez, R.; Amundadottir, L. E.; Malats, N.; Ortega, S.; Real, F. X.
10.1101/2024.07.23.604778 — cancer biology — Posted on 2024-07-24
1270 Genome admixture among four hare species in Iberia: focus on the broom hare (Lepus castroviejoi)
Souto, J.; Marques, J. P.; Farelo, L.; Costa, J.; Queiros, J.; Pietri, C.; Ballesteros, F.; Alves, P. C.; Boursot, P.; Melo-Ferreira, J.
10.1101/2024.07.23.604737 — evolutionary biology — Posted on 2024-07-24
1272 Leaf spectroscopy reveals drought response variation in Fagus sylvatica saplings from across the species' range
Kurath, D.; van Moorsel, S. J.; Klaver, J.; Voortman, T.; Siegried, B.; Bruegger, Y.-A.; Moradi, A.; Czyz, E. A.; de La Harpe, M.; Wiesenberg, G. L. B.; Schaepman, M. E.; Schuman, M. C.
10.1101/2024.07.23.604726 — ecology — Posted on 2024-07-24
1273 DNA polymerase {lambda}-driven targeted mutagenesis fordirected evolution in human cells
Aiello, D.; Ciciani, M.; Marelli, F.; Stancampiano, M.; De Sanctis, V.; Bertorelli, R.; Kheir, E. G. A.; Maule, G.; Cereseto, A.; Arosio, D.
10.1101/2024.07.23.604813 — molecular biology — Posted on 2024-07-24
1274 FISH, a new tool for in situ preservation of RNA in tissues of deep-sea mobile fauna.
Cueff-Gauchard, V.; Aube, J.; Lagadec, J.-R.; Bignon, L.; Lafontaine, J.-P.; Hernandez-Avila, I.; Marsaud, N.; Shillito, B.; Amand, L.; Roussel, E. G.; Cambon, M.-A.
10.1101/2024.07.23.604794 — molecular biology — Posted on 2024-07-24
1275 Protein Kinases MpkA and SepH Transduce Crosstalk Between CWI and SIN Pathways to Activate Protective Hyphal Septation Under Echinocandin Cell Wall Stress
Doan, A. G.; Schafer, J. E.; Douglas, C. M.; Quintanilla, M. S.; Morse, M. E.; Edwards, H.; Huso, W.; Gray, K. J.; Lee, J.; Dayie, J. K.; Harris, S.; Marten, M. R.
10.1101/2024.07.23.604799 — microbiology — Posted on 2024-07-24
1280 Destablisation of bam transcripts terminates the mitotic phase of Drosophila female germline differentiation
Samuels, T. J.; Torley, E. J.; Naden, E. L.; Blair, P. E.; Hernandez Frometa, F. A.; Karam Teixeira, F.
10.1101/2024.07.24.604138 — developmental biology — Posted on 2024-07-24
1282 Contrasting topologies of synchronous and asynchronous functional brain networks
McIntyre, C. C.; Bahrami, M.; Shappell, H. M.; Lyday, R. G.; Fish, J.; Bollt, E. M.; Laurienti, P. J.
10.1101/2024.07.23.604765 — neuroscience — Posted on 2024-07-24
1285 scRNA-seq identifies unique macrophage population in murine model of ozone induced asthma exacerbation
Ray, J. L.; Walum, J.; Jelic, D.; Barnes, R.; Bentley, I. D.; Britt, R. J.; Englert, J.; Ballinger, M. N.
10.1101/2024.07.23.604740 — pharmacology and toxicology — Posted on 2024-07-24
1290 Towards a new standard in genomic data privacy: a realization of owner-governance
Zhang, J.; Ren, Y.; Au, M. H.; Chow, K.-H.; Zhou, Y.; Chen, L.; Zhao, Y.; Su, J.; Luo, R.
10.1101/2024.07.23.604393 — bioinformatics — Posted on 2024-07-24
1291 Predicting real-world navigation performance from a virtual navigation task in older adults
Goodroe, S.; Fernandez Velasco, P.; Gahnstrom, C.; Wiener, J.; Coutrot, A.; Hornberger, M.; Spiers, H. J.
10.1101/2024.07.23.604766 — animal behavior and cognition — Posted on 2024-07-24
1298 Novel fluorescence-based methods to determine infarct and scar size in murine models of reperfused myocardial infarction
Duplessis, A.; Elster, C.; Becher, S.; Engel, C.; Lang, A.; Kaldirim, M.; Jung, C.; Grandoch, M.; Kelm, M.; Pfeiler, S.; Gerdes, N.
10.1101/2024.07.19.604384 — pathology — Posted on 2024-07-24
1302 Early and Delayed STAT1-Dependent Responses Drive Local Trained Immunity of Macrophages in the Spleen
Solomon, A.; Bossel Ben-Moshe, N.; Hoffman, D.; Trzebanski, S.; Yehezkel, D.; Vainman, L.; Netea, M. G.; Avraham, R.
10.1101/2024.07.19.604264 — immunology — Posted on 2024-07-24
1304 Therapeutic DBS for OCD Suppresses the Default Mode Network
Slepneva, N.; Basich-Pease, G.; Reid, L.; Frank, A. C.; Norbu, T.; Krystal, A. D.; Sugrue, L. P.; Motzkin, J. C.; Larson, P. S.; Starr, P. A.; Morrison, M. A.; Lee, A. M.
10.1101/2024.07.21.601827 — neuroscience — Posted on 2024-07-24
1305 Pulsed inhibition of corticospinal excitability by the thalamocortical sleep spindle
Hassan, U.; Okyere, P.; Masouleh, M. A.; Zrenner, C.; Ziemann, U.; Bergmann, T. O.
10.1101/2024.07.22.604668 — neuroscience — Posted on 2024-07-24
1307 Inflammatory Neuropathy in Mouse and Primate Models of Colorectal Cancer
Gaffney, C. M.; Casaril, A. M.; Mahmud, I.; Wei, B.; Valadez, K. M.; Kolb, E. A.; Cherry, F. R.; Guise, T. A.; Lorenzi, P. L.; Shi, L.; Hodo, C. L.; Shepherd, A. J.
10.1101/2024.07.19.604274 — neuroscience — Posted on 2024-07-24
1310 Synthetic dysmobility screening reveals a phosphorylation-independent facet of the SLK-Ezrin-F-actin signaling cascade.
LIN, H. C.; LIN, Y. Y.; WEI, L. Y.; ZHANG, J. M.; TSAI, P. J.; LIN, Y. C.; CHIA, J. S.; TSAI, F. C.
10.1101/2024.07.23.604488 — cell biology — Posted on 2024-07-24
1312 Coxsackievirus B infection invokes unique cell-type specific responses in primary human pancreatic islets
Veronese-Paniagua, D. A.; Hernandez-Rincon, D. C.; Taylor, J. P.; Tse, H. M.; Millman, J. R.
10.1101/2024.07.23.604861 — cell biology — Posted on 2024-07-24
1313 Sirt5 regulates chondrocyte metabolism and osteoarthritis development through protein lysine malonylation
Liu, H.; Binoy, A.; Ren, S.; Martino, T. C.; Miller, A. E.; Willis, C. R.; Veerabhadraiah, S. R.; Sukul, A.; Jurynec, M. J.; Zhu, S.
10.1101/2024.07.23.604872 — cell biology — Posted on 2024-07-24
1314 ATG9A and ARFIP2 cooperate to regulate PI4P levels for lysosomal repair
De Tito, S.; Almacellas, E.; Yu, D. D.; Zhang, W.; Millard, E.; Hervas, J. H.; Pellegrino, E.; Panagi, I.; Fodge, D.; Thurston, T. L. M.; Gutierrez, M.; Tooze, S.
10.1101/2024.07.23.604321 — cell biology — Posted on 2024-07-24
1315 Cell Storage Conditions Impact Single-Cell Proteomic Landscapes
Onat, B.; Momenzadeh, A.; Haghani, A.; Jiang, Y.; Song, Y.; Parker, S. J.; Meyer, J. G.
10.1101/2024.07.23.604834 — cell biology — Posted on 2024-07-24
1317 Oestrogen influences B cell class-switching in individuals with an XX sex chromosome complement
Peckham, H.; Radziszewska, A.; de Gruijter, N. M.; Restuadi, R.; Kartawinata, M.; Robinson, G. A.; Martin-Gutierrez, L.; Deakin, C. T.; Wedderburn, L. R.; Jury, E. C.; Butler, G.; Rosser, E. C.; Ciurtin, C.
10.1101/2024.07.18.604160 — immunology — Posted on 2024-07-24
1320 A Lipid Atlas of the Human Kidney
Farrow, M. A.; Tideman, L. E. M.; Neumann, E. K.; Migas, L. G.; Patterson, N. H.; Colley, M. E.; Allen, J. L.; Pingry, E. L.; Dufresne, M.; Yang, H.; Brewer, M.; Rivera, E. S.; Romer, C. E.; Djambazova, K.; Sharman, K.; Kruse, A. R. S.; Gutierrez, D. B.; Harris, R. C.; Fogo, A. B.; de Caestecker, M. P.; Caprioli, R. M.; Van de Plas, R.; Spraggins, J. M.
10.1101/2022.04.07.487155 — biochemistry — Posted on 2024-07-24
1322 A Comprehensive Resource for Exploring Antiphage Defense: DefenseFinder Webservice, Wiki and Databases.
Tesson, F.; Planel, R.; Egorov, A. A.; Georjon, H.; Vaysset, H.; Brancotte, B.; Neron, B.; Mordret, E.; Atkinson, G. C.; Bernheim, A.; Cury, J.
10.1101/2024.01.25.577194 — genomics — Posted on 2024-07-24
1323 Topological stress triggers persistent DNA lesions in ribosomal DNA with ensuing formation of PML-nucleolar compartment
Urbancokova, A.; Hornofova, T.; Novak, J.; Salajkova, S. A.; Stemberkova Hubackova, S.; Uvizl, A.; Buchtova, T.; Mistrik, M.; Mac Stay, B.; Hodny, Z.; Bartek, J.; Vasicova, P.
10.1101/2023.08.05.552131 — cell biology — Posted on 2024-07-24
1324 Pericytes promote more angiogenesis and vasculogenesis than mesenchymal stromal cells in microfluidic chips
Gonzalez-Rubio, J.; Kubiza, H.; Koenigs-Werner, H.; Jockenhoevel, S.; Cornelissen, C. G.; Thiebes, A. L.
10.1101/2023.11.02.565266 — cell biology — Posted on 2024-07-24
1326 Primate-specific BTN3A2 protects against SARS-CoV-2 infection by interacting with and reducing ACE2
Xu, L.; Yu, D.; Xu, M.; Yang, L.-X.; Zou, Q.-C.; Feng, X.-L.; Li, M.-H.; Sheng, N.; Yao, Y.-G.
10.1101/2024.01.13.575537 — cell biology — Posted on 2024-07-24
1327 IncC plasmid genome rearrangements influence the vertical and horizontal transmission tradeoff in Escherichia coli
Allain, M.; Morel-Journel, T.; Condamine, B.; Gibeaux, B.; Gachet, B.; GSCHWIND, R.; Denamur, E.; Landraud, L.
10.1101/2024.04.17.589899 — microbiology — Posted on 2024-07-24
1329 Cryptococcosis, tuberculosis, and a kidney cancer fail to fit the atherosclerosis paradigm for foam cell lipid content
Guerrini, V.; Prideaux, B.; Khan, R.; Subbian, S.; Wang, Y.; Sadimin, E.; Pawar, S.; Ukey, R.; Singer, E. A.; Xue, C.; Gennaro, M. L.
10.1101/2023.06.08.542766 — immunology — Posted on 2024-07-24
1331 Brain encoding of naturalistic, continuous, and unpredictable tactile events
Castellani, N.; Federici, A.; Fantoni, M.; Ricciardi, E.; Garbarini, F.; Bottari, D.
10.1101/2023.12.08.570756 — neuroscience — Posted on 2024-07-24
1338 Image-based force inference by biomechanical simulation
Vanslambrouck, M.; Thiels, W.; Vangheel, J.; van Bavel, C.; Smeets, B.; Jelier, R.
10.1101/2023.12.01.569682 — bioinformatics — Posted on 2024-07-24
1339 A generative foundation model for antibody sequence understanding
Barton, J.; Gaspariunas, A.; Yadin, D. A.; Dias, J.; Nice, F. L.; Minns, D. H.; Snudden, O.; Povall, C.; Valle Tomas, S.; Dobson, H.; Farmery, J. H.; Leem, J.; Galson, J. D.
10.1101/2024.05.22.594943 — bioinformatics — Posted on 2024-07-24
1340 Cryo-electron tomographic investigation of native hippocampal glutamatergic synapses
Matsui, A.; Spangler, C.; Elferich, J.; Shiozaki, M.; Jean, N.; Zhao, X.; Qin, M.; Zhong, H.; Yu, Z.; Gouaux, E.
10.1101/2024.04.01.587595 — biochemistry — Posted on 2024-07-24
1347 Hexokinase regulates Mondo-mediated longevity via the PPP and organellar dynamics
Laboy, R.; Ndoci, M.; Vonolfen, M.; Ballhysa, E.; syed, s. t.; droth, t.; schilling, k.; loehrke, a.; Atanassov, I.; Antebi, A.
10.1101/2023.06.14.544948 — cell biology — Posted on 2024-07-24
1349 Identification of culturable fungi and bacteria in mosquito saliva and impact on arbovirus infection in vitro
Wang, L.; Remue, L.; Trappeniers, K.; Verwimp, S.; Adriaens, N.; Rivas, F.; Soto, A.; van Bree, J.; Garigliany, M.; Delang, L.
10.1101/2023.03.31.534949 — microbiology — Posted on 2024-07-24
1350 Lung structural cell dynamics are altered by influenza virus infection experience leading to rapid immune protection following viral re-challenge
Worrell, J. C.; Hargrave, K. E.; Finney, G. E.; Hansell, C.; Cole, J. J.; Singh Niijar, J.; Morton, F. R.; Pingen, M.; Purnell, T.; Mitchelson, K.; Brennan, E.; Allan, J.; Ilia, G.; Herder, V.; Kennedy Dietrich, C.; Doncheva, Y.; Jamieson, N.; MacLeod, M. K.
10.1101/2024.07.20.604410 — immunology — Posted on 2024-07-24
1352 A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resist
Le Pen, J.; Paniccia, G.; Kinast, V.; Moncada-Velez, M.; Ashbrook, A. W.; Bauer, M.; Hoffmann, H.- H.; Pinharanda, A.; Ricardo-Lax, I.; Stenzel, A. F.; Rosado-Olivieri, E. A.; Dinnon, K. H.; Doyle, W. C.; Freije, C. A.; Hong, S.-H.; Lee, D.; Lewy, T.; Luna, J. M.; Peace, A.; Schmidt, C.; Schneider, W. M.; Winkler, R.; Yip, E. Z.; Larson, C.; McGinn, T.; Menezes, M.-R.; Ramos-Espiritu, L.; Banerjee, P.; Poirier, J. T.; Sanchez-Rivera, F. J.; Zhang, Q.; Casanova, J.-L.; Carroll, T. S.; Glickman, J. F.; Michailidis, E.; Razooky, B.; MacDonald, M. R.; Rice, C. M.
10.1101/2024.02.16.580725 — immunology — Posted on 2024-07-24
1353 The noncoding circular RNA circHomer1 regulates developmental experience-dependent plasticity in mouse visual cortex
Jenks, K. R.; Cai, Y.; Nayan, M. E.; Tsimring, K.; Li, K.; Zepeda, J. C.; Heller, G. R.; Delepine, C.; Shih, J.; Yuan, S.; Zhu, Y.; Wang, Y.; Duan, Y.; Fu, A. K. Y.; Ku, T.; Yun, D. H.; Chung, K.; Zhang, C.; Boyden, E. S.; Mellios, N.; Sur, M.; Ip, J. P. K.
10.1101/2024.07.19.603416 — neuroscience — Posted on 2024-07-24
1355 Prioritizing Maize Metabolic Gene Regulators through Multi-Omic Network Integration
Gomez-Cano, F. A.; Rodriguez, J.; Zhou, P.; Chu, Y.-H.; Magnusson, E.; Gomez-Cano, L.; Krishnan, A.; Springer, N. M.; de Leon, N.; Grotewold, E.
10.1101/2024.02.26.582075 — plant biology — Posted on 2024-07-24
1356 Deciphering drug response and phenotypic heterogeneity of cancer cells using gene ensembles of regulatory units defined by chromatin domains
Pandey, N.; Sharma, M.; Mathur, A.; Nzelu, G. A.; Hakimullah, M.; Jha, I. P.; Chandra, O.; Mishra, S.; Bhattacharya, J.; Sharma, A.; Foo, R.; Sandhu, K. S.; Mandoli, A.; DasGupta, R.; KUMAR, V.
10.1101/2023.01.15.524115 — cancer biology — Posted on 2024-07-24
1362 Paralemmin-1 controls the nanoarchitecture of the neuronal submembrane cytoskeleton
Macarron-Palacios, V.; Hubrich, J.; do Rego Barros Fernandes Lima, M. A.; Metzendorf, N. G.; Kneilmann, S.; Trapp, M.; Acuna, C.; Patrizi, A.; D'Este, E.; Kilimann, M. W.
10.1101/2024.07.23.604764 — cell biology — Posted on 2024-07-23
1366 Induction of cytoplasmic dsDNA and cGAS-STING immune signaling after exposure of breast cancer cells to X-rays or high energetic carbon ions
Totis, C.; Averbeck, N. B.; Jakob, B.; Schork, M.; Volpi, G.; Hintze, D. F.; Durante, M.; Fournier, C.; Helm, A.
10.1101/2024.07.23.604756 — biophysics — Posted on 2024-07-23
1369 A chemical-genetic system to rapidly inhibit the PP2A-B56 phosphatase
Allan, L.; Corno, A.; Valverde, J. M.; Toth, R.; Ly, T.; Saurin, A. T.
10.1101/2024.07.23.604754 — cell biology — Posted on 2024-07-23
1370 Laue-DIALS: open-source software for polychromatic X-ray diffraction data
Hewitt, R. A.; Dalton, K. M.; Mendez, D.; Wang, H. K.; Klureza, M. A.; Brookner, D. E.; Greisman, J. B.; McDonagh, D.; Srajer, V.; Sauter, N. K.; Brewster, A. S.; Hekstra, D. R.
10.1101/2024.07.23.604358 — molecular biology — Posted on 2024-07-23
1374 Computationally designed mRNA-launched protein nanoparticle vaccines
Hendricks, G. G.; Grigoryan, L.; Navarro, M. J.; Catanzaro, N. J.; Hubbard, M. L.; Powers, J. M.; Mattocks, M.; Treichel, C.; Walls, A. C.; Lee, J.; Ellis, D.; Wang, J. Y.; Cheng, S.; Miranda, M. C.; Valdez, A.; Chao, C. W.; Chan, S.; Men, C.; Johnson, M. R.; Hui, H.; Wu, S.-Y.; Lujan, V.; Muramatsu, H.; Lin, P. J. C.; Sung, M. M. H.; Tam, Y. K.; Leaf, E. M.; Pardi, N.; Baric, R. S.; Pulendran, B.; Veesler, D.; Schäfer, A.; King, N. P.
10.1101/2024.07.22.604655 — immunology — Posted on 2024-07-23
1378 PA2gamma promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP
Wang, J.; Shi, Y.; Wang, Y.; Shen, Y.; Liu, H.; Sun, S.; Wang, Y.; Zhou, X.; Zhou, Y.; Zeng, X.; Li, J.; Chen, Q.
10.1101/2024.07.23.604769 — cancer biology — Posted on 2024-07-23
1383 Demultiplexing and barcode-specific adaptive sampling for nanopore direct RNA sequencing
van der Toorn, W.; Bohn, P.; Liu-Wei, W.; Olguin-Nava, M.; Smyth, R. P.; von Kleist, M.
10.1101/2024.07.22.604276 — bioinformatics — Posted on 2024-07-23
1385 Pheno-morphological screening and acoustic sorting of 3D multicellular aggregates using drop millifluidics
Rembotte, L.; Beneyton, T.; Buisson, L.; Badon, A.; Boyreau, A.; Douillet, C.; Hermant, L.; Jana, A.; Nassoy, P.; Baret, J.-C.
10.1101/2024.07.22.604529 — bioengineering — Posted on 2024-07-23
1386 Bacterial cell cycle regulator MatP forms biomolecular condensates and directly interacts with cell division protein FtsZ
Barros-Medina, I.; Robles-Ramos, M. A.; Sobrinos-Sanguino, M.; Luque-Ortega, J. R.; Alfonso, C.; Margolin, W.; Rivas, G.; Monterroso, B.; Zorrilla, S.
10.1101/2024.07.23.604758 — biochemistry — Posted on 2024-07-23
1387 FAAH Inhibition as a Path to Mitigate Alzheimer's Disease Progression in Mouse Models of Amyloidosis
Oddi, S.; Scipioni, L.; Totaro, A.; Giacovazzo, G.; Ciaramellano, F.; Tortolani, D.; Leuti, A.; Businaro, R.; Armeli, F.; Bilkei-Gorzo, A.; Coccurello, R.; Zimmer, A.; Maccarrone, M.
10.1101/2024.07.23.604774 — biochemistry — Posted on 2024-07-23
1388 Unusual traits shape the architecture of the Ig ancestor molecule
Urdiciain, A.; Madej, T.; Wang, J.; Song, J.; Erausquin, E.; Youkharibache, P.; Lopez-Sagaseta, J.
10.1101/2024.07.22.604567 — evolutionary biology — Posted on 2024-07-23
1390 ASO-mediated knockdown of GPNMB in mutant-GRN and Grn-deficient peripheral myeloid cells disrupts lysosomal function and immune responses
Wallings, R.; Gillett, D. A.; Staley, H.; Mahn, S.; Mark, J.; Neighbarger, N.; kordasiewicz, H.; Hirst, W. D.; Tansey, M. G.
10.1101/2024.07.22.604676 — immunology — Posted on 2024-07-23
1393 Interplay of Light, Melatonin, and Circadian Genes in Skin Pigmentation Regulation
Bertolesi, G. E.; Debnath, N.; Heshami, N.; Bui, R.; Zadeh-Haghighi, H.; Simon, C.; McFarlane, S.
10.1101/2024.07.22.604624 — physiology — Posted on 2024-07-23
1395 Cleavage region organizes the structural architecture of the B2 SINE ribozyme
Singhal, A.; Mrozowich, T.; Chaudhury, S. N.; Rivera, C.; Badmalia, M.; Lee, J. T.; Patel, T. R.; Sanbonmatsu, K.
10.1101/2024.07.22.604665 — biophysics — Posted on 2024-07-23
1398 Hexokinase-I directly binds to a charged membrane-buried glutamate of mitochondrial VDAC1 and VDAC2
Holthuis, J. C. M.; Bieker, S.; Timme, M.; Woge, N.; Hassan, D. G.; Brown, C. M.; Marrink, S.-J.; Melo, M. N.
10.1101/2024.07.22.604557 — biochemistry — Posted on 2024-07-23
1401 Murine aortic valve cell heterogeneity at birth
Lincoln, J.; Bluemn, T.; Kessler, J. R.; Kim, A. J.; Drnevich, J.
10.1101/2024.07.22.604705 — cell biology — Posted on 2024-07-23
1403 Integrating in silico predictions with an engineered tissue assay identifies Perlecan as an age-perturbed re-quiescence cue for muscle stem cells
Jacques, E.; Garcia, P.; Mercier, O.; Hu, Y.; Degletagne, C.; Ravent, J.; Fall, S.; Almeida, M. P.; Wheeler, A. R.; Angers, S.; Gilbert, P. M.; Le Grand, F.
10.1101/2024.07.22.604619 — cell biology — Posted on 2024-07-23
1405 Transiently boosting Vγ9+Vδ2+ γδ T cells early in Mtb coinfection of SIV-infected juvenile macaques does not improve Mtb host resistance.
Larson, E. C.; Ellis, A.; Rodgers, M.; Gubernat, A. K.; Gleim, J. L.; Moriarty, R. V.; Balgeman, A. J.; Menezes, Y. K.; Ameel, C.; Fillmore, D. J.; Pergalske, S. M.; Juno, J. A.; Maiello, P.; Chishti, H. B.; Lin, P. L.; Godfrey, D. I.; Kent, S. J.; Pellicci, D.; NDHLOVU, L. C.; O'Connor, S. L.; Scanga, C. A.
10.1101/2024.07.22.604654 — immunology — Posted on 2024-07-23
1406 A Hypothalamic Circuit that Modulates Feeding and Parenting Behaviors
Alcantara, I. C.; Li, C.; Mickelsen, L. E.; Mazzone, C. M.; de Araujo Salgado, I.; Gao, C.; Papas, B. N.; Xiao, C.; Karolczak, E. O.; Goldschmidt, A. I.; Rodriguez Gonzalez, S.; Pinol, R. A.; Li, J.-L.; Cui, G.; Reitman, M. L.; Krashes, M. J.
10.1101/2024.07.22.604437 — neuroscience — Posted on 2024-07-23
1407 Enhanced restoration of visual code after targeting on bipolar cells compared to retinal ganglion cells with optogenetic therapy
Rodgers, J.; Hughes, S.; Ebrahimi, A.; Allen, A. E.; Storchi, R.; Lindner, M.; Peirson, S. N.; Badea, T. C.; Hankins, M. W.; Lucas, R. J.
10.1101/2024.07.22.604613 — neuroscience — Posted on 2024-07-23
1409 Sympathetic Nervous System Overactivation Induces Colonic Eosinophil-Associated Microinflammation and Contributes to the Pathogenesis of Irritable Bowel Syndrome
Duan, S.; Kanda, H.; Zhu, F.; Okubo, M.; Koike, T.; Ohno, Y.; Tanaka, T.; Harima, Y.; Miyamichi, K.; Fukui, H.; Shinzaki, S.; Cui, Y.; Noguchi, K.; Dai, Y.
10.1101/2024.07.22.604223 — neuroscience — Posted on 2024-07-23
1412 Control of cholesterol-induced adipocyte inflammation by the Nfe2l1-Atf3 pathway
Jethwa, C.; Hoffmann, A.; Kotschi, S.; Caesar, J.; Kern, M.; Worthmann, A.; Schlein, C.; Khani, S.; Arus, B. A.; Bruns, O. T.; Ghosh, A.; Wolfrum, C.; Döring, Y.; Herzig, S.; Weber, C.; Blüher, M.; Widenmaier, S. B.; Hotamıslıgil, G. S.; Bartelt, A.
10.1101/2024.07.22.604614 — physiology — Posted on 2024-07-23
1413 Impact of vertebrate host parasitaemia on Plasmodium development within mosquitoes
Isaia, J.; Baur, M.; Wassef, J.; Monod, S.; Glaizot, O.; Christe, P.; Pigeault, R.
10.1101/2024.07.22.604581 — pathology — Posted on 2024-07-23
1414 Preclinical Pediatric Molecular Analysis for Therapy Choice (MATCH)
Blankenship, K.; Chang, T.-C.; Fan, Y.; Gordon, B.; Wright, W. C.; Kieffer, M.; Karlstrom, A.; Jeon, J.; Patel, A.; Dapper, J.; Caufield, W. V.; Freeman, B. B.; Federico, S.; Clay, M. R.; Wu, G. G.; Zhou, X.; Hoffmann, L.; Geeleher, P.; Dyer, M. A.; McEvoy, J.; Stewart, E. A.
10.1101/2024.07.22.604648 — cancer biology — Posted on 2024-07-23
1415 Systematic profiling of the acetyl lysine machinery reveals a role for MAPKAPK2 in bromodomain inhibitor resistance
Kougnassoukou Tchara, P.-E.; Loehr, J.; Germain, L.; Steinhart, Z.; Gonzalez-Badillo, B.; Lashgari, A.; Chartier, F. J. M.; Tucholska, M.; Picaud, S.; Knight, J. D. R.; Angers, S.; Bisson, N.; Goding, C. R.; Audet-Walsh, E.; Filippakopoulos, P.; Gingras, A.-C.; Lambert, J.-P.
10.1101/2024.07.22.604604 — cancer biology — Posted on 2024-07-23
1420 Bacterial Wastewater-Based Epidemiology Using Surface-Enhanced Raman Spectroscopy and Machine Learning
Herndon, L. K.; Zhang, Y.; Safir, F.; Ogunlade, B.; Balch, H. B.; Boehm, A.; Dionne, J. A.
10.1101/2024.07.22.604506 — bioengineering — Posted on 2024-07-23
1422 STK19 positions TFIIH for cell-free transcription-coupled DNA repair
Mevissen, T. E. T.; Kuemmecke, M.; Schmid, E. W.; Farnung, L.; Walter, J. C.
10.1101/2024.07.22.604623 — biochemistry — Posted on 2024-07-23
1425 Boosting the Predictive Power of Protein Representations with a Corpus of Text Annotations
Duan, H.; Skreta, M.; Cotta, L.; Rajaonson, E. M.; Dhawan, N.; Aspuru-Guzik, A.; Maddison, C. J.
10.1101/2024.07.22.604688 — biochemistry — Posted on 2024-07-23
1426 A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo
Tilley, L.; Xie, S. C.; Tai, C.-W.; Morton, C. J.; Ma, L.; Huang, S.-C.; Wittlin, S.; Du, Y.; Hu, Y.; Dogovski, C.; Salimimarand, M.; Griffin, R.; England, D.; de la Curz, E.; Deni, I.; Yeo, T.; Burkhard, A. Y.; Striepen, J.; Schindler, K. A.; Crespo, B.; Gamo, F. J.; Khandokar, Y.; Hutton, C. A.; Rabie, T.; Birkholtz, L.-M.; Famodimu, M. T.; Delves, M. J.; Bolsher, J.; Koolen, K. M. J.; van der Laak, R.; Aguiar, A. C. C.; Pereira, D. B.; Creek, D. J.; Fidock, D. A.; Dick, L. R.; Brand, S. L.; Gould, A. E.; Langston, S.; Griffin, M. D. W.
10.1101/2024.07.22.604682 — biochemistry — Posted on 2024-07-23
1427 Parametrically guided design of beta barrels and transmembrane nanopores using deep learning
Kim, D. E.; Watson, J. L.; Juergens, D.; Majumder, S.; Gerben, S. R.; Kang, A.; Bera, A. K.; Li, X.; Baker, D.
10.1101/2024.07.22.604663 — biochemistry — Posted on 2024-07-23
1430 Stimulation of locus coeruleus inputs to the frontal cortex in mice induces cell type-specific expression of the Apoe gene
Craig, G. E.; Ramos, L.; Essig, S. R.; Eagles, N. J.; Jaffe, A. E.; Martinowich, K.; Hallock, H. L.
10.1101/2024.07.22.604695 — genetics — Posted on 2024-07-23
1431 Genetic variants affect diurnal glucose levels throughout the day
Sinnott-Armstrong, N.; Strausz, S.; Urpa, L.; Abner, E.; Valliere, J.; Estonian Biobank Research Team, ; Palta, P.; Dashti, H. S.; Daly, M.; Pritchard, J. K.; Saxena, R.; Jones, S. E.; Ollila, H. M.
10.1101/2024.07.22.604631 — genetics — Posted on 2024-07-23
1432 Molecular and structural innovations of the stator motor complex at the dawn of flagellar motility
Puente-Lelievre, C.; Ridone, P.; Douglas, J.; Amritkar, K.; Kacar, B.; Baker, M. A.; Matzke, N. J.
10.1101/2024.07.22.604496 — evolutionary biology — Posted on 2024-07-23
1433 Convergent expansions of keystone gene families drive metabolic innovation in a major eukaryotic clade
David, K. T.; Schraiber, J. G.; Crandall, J. G.; LaBella, A. L.; Opulente, D. A.; Harrison, M.-C.; Wolters, J. F.; Zhou, X.; Shen, X.-X.; Groenewald, M.; Hittinger, C. T.; Pennell, M.; Rokas, A.
10.1101/2024.07.22.604484 — evolutionary biology — Posted on 2024-07-23
1434 Size evolution of gigantic genomes suggests stochastic outcomes of transposable element/host silencing interactions
Wang, J.; Zhang, G.; Sun, C.; Chang, L.; Wang, Y.; Yang, X.; Chen, G.; Itgen, M. W.; Haley, A.; Tang, J.; Mueller, R. L.
10.1101/2024.07.22.604708 — evolutionary biology — Posted on 2024-07-23
1438 Relevance of the synergy of surveillance and populational networks in understanding the Usutu virus outbreak within common blackbirds (Turdus merula) in Metropolitan France, 2018
Bouchez-Zacria, M.; Calenge, C.; Villers, A.; Lecollinet, S.; Gonzalez, G.; Quintard, B.; Leclerc, A.; Baurier, F.; Paty, M.-C.; Faure, E.; Eraud, C.; Decors, A.
10.1101/2024.07.22.604715 — ecology — Posted on 2024-07-23
1441 Cell cycle-driven transcriptome maturation confers multilineage competence to cardiopharyngeal progenitors
Bernadskaya, Y. Y.; Kuan, A.; Tjarnberg, A.; Brandenburg, J.; Zheng, P.; Wiechecki, K.; Kaplan, N.; Failla, M.; Bikou, M.; Madilian, O.; Wang, W.; Christiaen, L.
10.1101/2024.07.23.604718 — developmental biology — Posted on 2024-07-23
1444 Aerobic methane production by methylotrophic Methylotenera in groundwater
Li, S.; Dong, X.; Humez, P.; Borecki, J.; Birks, J.; McClain, C.; Mayer, B.; Strous, M.; Diao, M.
10.1101/2024.07.22.604536 — microbiology — Posted on 2024-07-23
1445 Dietary iron deficiency impairs effector function of memory T cells following influenza infection
Bradley, M. C.; Gray, J.; La Carpia, F.; Idzikowski, E.; Guyer, R.; Pethe, K.; Hod, E.; Connors, T. J.
10.1101/2024.07.22.604599 — immunology — Posted on 2024-07-23
1448 Nanoscale organization is changed in native, surface AMPARs by mouse brain region and tauopathy
Vaidya, R. M.; Zhang, J.; Nall, D.; Lee, Y.; Kim, E. C.; Ma, D.; Huang, F.; Nonaka, H.; Kiyonaka, S.; Hamachi, I.; Chung, H. J.; Selvin, P. R.
10.1101/2024.07.22.604547 — neuroscience — Posted on 2024-07-23
1452 A disinhibitory basal forebrain to cortex projection supports sustained attention
Li, S.-J.; Hangya, B.; Gupta, U.; Fischer, K. B.; Sturgill, J. F.; Callaway, E. M.; Kepecs, A.
10.1101/2024.07.22.604711 — neuroscience — Posted on 2024-07-23
1454 Multi trait assessment of wheat variety mixtures performance and stability: mixtures for the win!
Stefan, L.; Strebel, S.; Camp, K.-H.; Christinat, S.; Fossati, D.; Staedeli, C.; Levy Haener, L.
10.1101/2024.07.22.604587 — plant biology — Posted on 2024-07-23
1455 Linking stomatal size and density to water use efficiency and leaf carbon isotope ratio in juvenile and mature trees
Petrik, P.; Petek-Petrik, A.; Lamarque, L. J.; Waite, P.-A.; Link, R. M.; Ruehr, N. K.; Schuldt, B.; Maire, V.
10.1101/2024.07.22.604523 — plant biology — Posted on 2024-07-23
1456 Off-the-shelf image analysis models outperform human visual assessment in identifying genes controlling seed color variation in sorghum
Shrestha, N.; Mangal, H.; Torres-Rodriguez, J. V.; Tross, M. C.; Lopez-Corona, L.; Linders, K.; Sun, G.; Mural, R. V.; Schnable, J. C.
10.1101/2024.07.22.604683 — plant biology — Posted on 2024-07-23
1460 The Orphan G Protein-Coupled Receptor GPR52 is a Novel Regulator of Breast Cancer Multicellular Organization
Hanif, S. Z.; Au, C. C.; Torregroza, I.; Jannath, S.; Fabiha, T.; Bhinder, B.; Washburn, M.; Devost, D.; Liu, S.; Bhardwaj, P.; Evans, T.; Anand, P. K.; Tarran, R.; Palikhe, S.; Elemento, O.; Dow, L. E.; Blenis, J.; Hebert, T.; Brown, K. A.
10.1101/2024.07.22.604482 — cancer biology — Posted on 2024-07-23
1463 Transient Non-local Interactions Dominate the Dynamics of Measles Virus NTAIL
Otteson, L.; Nagy, G.; Kunkel, J.; Kodis, G.; Zheng, W.; Bignon, C.; Longhi, S.; Grubmüller, H.; Vaiana, A. C.; Vaiana, S. M.
10.1101/2024.07.22.604679 — biophysics — Posted on 2024-07-23
1465 dsRNAEngineer: a web-based tool of comprehensive dsRNA design for pest control
Chen, Y.; Shi, Y.; Wang, Z.; An, X.; Wei, S.; Andronis, C.; Vontas, J.; Wang, J.-j.; Niu, J.
10.1101/2024.07.22.604585 — bioinformatics — Posted on 2024-07-23
1469 Engineered microvasculature using maskless photolithography and on-chip hydrogel patterning: a facile approach
Kasi, D. G.; de Graaf, M. N. S.; Nahon, D. M.; van den Hil, F. E.; van den Maagdenberg, A. M. J. M.; Mummery, C. L.; Orlova, V. V.
10.1101/2024.07.22.604661 — bioengineering — Posted on 2024-07-23
1472 Long-distance gene flow and recombination shape the evolutionary history of a maize pathogen
Rogerio, F.; Oosterhout, C. V.; De Mita, S.; Cuevas-Fernandez, F. B.; Garcia-Rodriguez, P.; Becerra, S.; Gutierrez-Sanchez, S.; Jacquat, A. G.; Bettiol, W.; Hosaka, G. K.; Ulla, S. B.; Hiltbrunner, J.; Santiago, R.; Revilla, P.; Dambolena, J. S.; Vicente-Villardon, J. L.; Buhinicek, I.; Sukno, S. A.; Thon, M. R.
10.1101/2024.07.22.604531 — genomics — Posted on 2024-07-23
1473 Population genetic structure of the aphid pest Myzus persicae in organic and conventional greenhouses
Beekman, M. M.; van den Heuvel, J.; Donner, S. H.; Litjens, J. J. H.; Dicke, M.; Zwaan, B. J.; Verhulst, E. C.; Pannebakker, B. A.
10.1101/2024.07.22.604537 — genetics — Posted on 2024-07-23
1474 Glycaemia and albumin glycation rates as fitness mediators in the wild: the case of a long-lived bird
Moreno Borrallo, A.; Bize, P.; Jaramillo Ortiz, S.; Schaeffer-Reiss, C.; Bertile, F.; Criscuolo, F.
10.1101/2024.07.22.604617 — evolutionary biology — Posted on 2024-07-23
1476 Operational lessons learned from simulating an elimination response to a transboundary animal disease in wild animals
Chalkowski, K.; Pepin, K. M.; Lavelle, M. J.; Miller, R. S.; Fischer, J. W.; Brown, V. R.; Glow, M. P.; Smith, B.; Cook, S.; Kohen, K.; Sherburne, S.; Smith, H.; Leland, B. R.; VerCauteren, K. C.; Snow, N. P.
10.1101/2024.07.22.604666 — ecology — Posted on 2024-07-23
1478 Sputum Proteomics reveals unique signatures linked to key outcomes in cystic fibrosis trials.
Pottenger, S.; Nazareth, D.; Wat, D.; Bellina, B.; Langini, M.; Walshaw, M.; Neill, D. R.; Schwarz, C.; Frost, F.; Fothergill, J. L.
10.1101/2024.07.23.604741 — immunology — Posted on 2024-07-23
1481 Experimentally induced pain and paresthesia respond differently to cuff-based compression
Skalski, J.; Swoboda, S.; Szikszay, T.; Wodarski, P.; Bieniek, A.; Luedtke, K.; Adamczyk, W. M.
10.1101/2024.07.22.604622 — physiology — Posted on 2024-07-23
1488 An arylsulphonamide that targets cell wall biosynthesis in Mycobacterium tuberculosis
Allen, R.; Ames, L.; Baldin, V. P.; Butts, A.; Henry, K. J.; Quach, D.; Sugie, J.; Pogliano, J.; Parish, T.
10.1101/2024.07.22.604653 — microbiology — Posted on 2024-07-23
1492 Synapse protein signatures in cerebrospinal fluid and plasma predict cognitive maintenance versus decline in Alzheimers disease
Oh, H. S.-H.; Urey, D. Y.; Karlsson, L.; Zhu, Z.; Shen, Y.; Farinas, A.; Timsina, J.; Guldner, I. H.; Morshed, N.; Yang, C.; Western, D.; Ali, M.; Le Guen, Y.; Trelle, A.; Herukka, S.-K.; Rauramaa, T.; Hiltunen, M.; Lipponen, A.; Luikku, A. J.; Poston, K. L.; Mormino, E.; Wagner, A. D.; Wilson, E. N.; Channappa, D.; Leinonen, V.; Stevens, B.; Ehrenberg, A. J.; Zetterberg, H.; Bennett, D. A.; Franzmeier, N.; Hansson, O.; Cruchaga, C.; Wyss-Coray, T.
10.1101/2024.07.22.604680 — neuroscience — Posted on 2024-07-23
1494 Functional gene embeddings improve rare variant polygenic risk scores
Londhe, S.; Lindner, J.; Chen, Z.; Holtkamp, E.; Holzlwimmer, F. R.; Casale, F. P.; Brechtmann, F.; Gagneur, J.
10.1101/2024.07.22.604535 — genetics — Posted on 2024-07-23
1495 Long shared haplotypes identify the Southern Urals as a primary source for the 10th century Hungarians
Gyuris, B.; Vyazov, L.; Türk, A.; Flegontov, P.; Szeifert, B.; Lango, P.; Mende, B. G.; Csaky, V.; Chizhevskiy, A. A.; Gazimzyanov, I. R.; Khokhlov, A. A.; Kolonskikh, A. G.; Matveeva, N. P.; Ruslanova, R. R.; Rykun, M. P.; Sitdikov, A.; Volkova, E. V.; Botalov, S. G.; Bugrov, D. G.; Grudochko, I. V.; Komar, O.; Krasnoperov, A. A.; Poshekhonova, O. E.; Chikunova, I.; Sungatov, F.; Stashenkov, D. A.; Zubov, S.; Zelenkov, A. S.; Ringbauer, H.; Cheronet, O.; Pinhasi, R.; Akbari, A.; Rohland, N.; Mallick, S.; Reich, D.; Szecsenyi-Nagy, A.
10.1101/2024.07.21.599526 — genetics — Posted on 2024-07-23
1499 Dengue virus structural proteins are expressed on the surface of DENV-infected cells and are a target for antibody-dependent cellular phagocytosis
Waldran, M. J.; Kurtz, E. A.; Gebo, C. J.; Rooney, T. J.; Middleton, F. A.; Roy, N. H.; Currier, J. R.; Waickman, A. T.
10.1101/2024.07.21.604479 — immunology — Posted on 2024-07-23
1500 Inhibiting monocyte migration reduces arterial thrombosis and facilitates thrombolysis
JANG, H. J.; Kim, J.; Kim, H.; Chung, J.; Kim, T.; Cremer, S.; Krohn-Grimberghe, M.; Schellingerhout, D.; Nahrendorf, M.; Kim, D.-E.
10.1101/2024.07.21.604499 — immunology — Posted on 2024-07-23
1502 Characterizing the heterogeneity of neurodegenerative diseases through EEG normative modeling
HASSAN, M.; Tabbal, J.; Ebadi, A.; Mheich, A.; Kabbara, A.; Guntekin, B.; Yener, G.; Paban, V.; Gschwandtner, U.; Fuhr, P.; Verin, M.; Babiloni, C.; Allouch, S.
10.1101/2024.07.22.604542 — neuroscience — Posted on 2024-07-23
1504 Patterns of Ongoing Thought in the Real World and Their Link to Mental Health and Well-Being
Mulholland, B.; Chitiz, L.; Wallace, R.; Mckeown, B.; Milham, M.; Klein, A.; Leech, R.; Jefferies, E.; Poerio, G.; Wammes, J.; Smallwood, J.
10.1101/2024.07.22.604681 — neuroscience — Posted on 2024-07-23
1505 ERβ mediates sex-specific protection in the App-NL-G-F mouse model of Alzheimer's disease
Demetriou, A.; Lindqvist, B.; Ali, H. G.; Shamekh, M. M.; Maioli, S.; Inzunza, J.; Varshney, M.; Nalvarte, I.
10.1101/2024.07.22.604543 — neuroscience — Posted on 2024-07-23
1508 A Suite of Biochemical and Cell-Based Assays for the Characterization of KRAS Inhibitors and Degraders
Kidane, M.; Hoffman, R. M.; Wolfe-Demarco, J. K.; Huang, T.-Y.; Teng, C.-L.; Gonzalez Lira, L. M.; Lin-Jones, J.; Pallares, G.; Lamerdin, J. E.; Servant, N. B.; Lee, C.-Y.; Yang, C.-T.; Bernatchez, J. A.
10.1101/2024.07.20.604418 — pharmacology and toxicology — Posted on 2024-07-23
1510 The multifaceted process of human coronary atherosclerotic cap destabilisation
Bruijn, L. E.; Fonseca Neves, N.; van Rhijn, C. M.; Hamming, J.; van den Bogaerdt, A.; Lindeman, J.
10.1101/2024.07.21.604507 — pathology — Posted on 2024-07-23
1511 An extinct clade sister to Eumetazoa: On the phylogeny of the Cambrian chancelloriids
Yun, H.; Zhang, X.; Brock, G. A.; Han, J.; Li, L.; Pan, B.; Li, G.; Reitner, J.
10.1101/2024.07.22.604532 — paleontology — Posted on 2024-07-23
1512 Manipulating the EphB4-ephrinB2 axis to reduce metastasis in HSNCC
Abdelazeem, K. N. M.; Nguyen, D.; Corbo, S.; Darragh, L.; Matsumoto, M. W.; Vancourt, B.; Neupert, B.; Yu, J.; Olimpo, N.; Osborne, D. G.; Gadwa, J.; Ross, R. B.; Nguyen, A.; Bhatia, S.; Kapoor, M.; Friedman, R. S.; Jacobelli, J.; Saviola, A. J.; Knitz, M. W.; Pasquale, E. B.; Karam, S. D.
10.1101/2024.07.21.604518 — cancer biology — Posted on 2024-07-23
1516 Cannabidiol reverses fentanyl-induced addiction and modulates neuroinflammation
Bhandari, B.; Chagas, H. I. S.; Naeini, S. E.; Chagas, P. S.; Rogers, H. M.; Gouron, J.; Khan, A.; Maciel, L. M.; Seyyedi, M.; MacKinnon, N. J.; Khodadadi, H.; Salles, E. L.; Hess, D. C.; Morgan, J. C.; Yu, J. C.; Wang, L. P.; Baban, B.
10.1101/2024.07.20.604441 — animal behavior and cognition — Posted on 2024-07-23
1518 Telomere-to-telomere sheep genome assembly reveals new variants associated with wool fineness trait
Luo, L.-Y.; Wu, H.; Zhao, L.-M.; Zhang, Y.-H.; Huang, J.-H.; Liu, Q.-Y.; Wang, H.-T.; Mo, D.-X.; EEr, H.-H.; Zhang, L.-Q.; Chen, H.-L.; Jia, S.-G.; Wang, W.-M.; Li, M.-H.
10.1101/2024.07.21.604451 — genomics — Posted on 2024-07-23
1519 Click-chemistry-aided quantitation and sequencing of oxidized guanines and apurinic sites uncovers their transcription-linked strand bias in human cells
Takhaveev, V.; Püllen, N. J. L.; Singh, N. K.; Huber, S. M.; Schauer, S.; Gahlon, H. L.; Poetsch, A. R.; Sturla, S. J.
10.1101/2024.07.21.604463 — genomics — Posted on 2024-07-23
1520 The role of methylation and structural variants in shaping the recombination landscape of barley
Casale, F. A.; Arlt, C.; Kuehl, M.; Li, J.; Engelhorn, J.; Hartwig, T.; Stich, B.
10.1101/2024.07.22.604552 — genomics — Posted on 2024-07-23
1521 Relative fire-proneness of land cover types in the Brazilian Atlantic Forest
Adorno, B. F.; Piratelli, A. A.; Hasui, E.; Ribeiro, M. C.; Vaz, P. G.
10.1101/2024.07.21.604452 — ecology — Posted on 2024-07-23
1526 Controlled pH Alteration Enables Guanine Accumulation and Drives Crystallization within Iridosomes
Eyal, Z.; Ggorelick-Ashkenazi, A.; Deis, R.; Barzilay, Y.; Broder, Y.; Kellum, A. P.; Varsano, N.; Hartstein, M.; Sorrentino, A.; Kaplan-Ashiri, I.; Rechav, K.; Metzler, R.; Houben, L.; Kronik, L.; Rez, P.; Gur, D.
10.1101/2024.07.20.604036 — cell biology — Posted on 2024-07-23
1529 A high-performance genetically encoded sensor for cellular imaging of PKC activity in vivo
Yahiro, T.; Bayless-Edwards, L.; Jones, J. A.; Ma, L.; Qin, M.; Mao, T.; Zhong, H.
10.1101/2024.07.19.604387 — neuroscience — Posted on 2024-07-23
1530 predicTTE: An accessible and optimal tool for time-to-event prediction in neurological diseases
Weinreich, M.; McDonough, H.; Yacovzada, N.; Magen, I.; Cohen, Y.; Harvey, C.; Gornall, S.; Boddy, S.; Alix, J.; Mohseni, N.; Kurz, J.; Kenna, K.; Zhang, S.; Iacoangeli, A.; Al-Khleifat, A.; Snyder, M.; Hobson, E.; Al-Chalabi, A.; Hornstein, E.; Elhaik, E.; Shaw, P.; McDermott, C.; Cooper-Knock, J.
10.1101/2024.07.20.604416 — neuroscience — Posted on 2024-07-23
1532 Modulation Of SUDEP By Central Serotonergic Cooperating with Noradrenergic Circuits: A Synergistic-Dependent Manner
Xu, Q.; Xu, X.; Wu, Y.; Yang, Y.; Gu, L.; Zhang, Z.; Zhang, Z.; Di, X.; Wang, Y.; Yu, Q.; Lian, X.; Ma, H.; Zhang, H.
10.1101/2024.07.20.604434 — neuroscience — Posted on 2024-07-23
1534 Context-driven interaction retrieval and classification for modeling, curation, and reuse
Luo, H.; Hansen, C.; Telmer, C. A.; Tang, D.; Arazkhani, N.; Zhou, G.; Spirtes, P.; Miskov-Zivanov, N.
10.1101/2024.07.21.604448 — systems biology — Posted on 2024-07-23
1535 Deletion of wheat alpha-gliadins from chromosome 6D improves gluten strength and reduces immunodominant celiac disease epitopes
Rottersman, M. G.; Zhang, W.; Zhang, J.; Grigorian, G.; Burguener, G.; Carter, C.; Vang, T.; Hegarty, J.; Zhang, X.; Dubcovsky, J.
10.1101/2024.07.19.604379 — plant biology — Posted on 2024-07-23
1536 A Ketogenic Diet Sensitizes Pancreatic Cancer to Inhibition of Glutamine Metabolism
Hajihassani, O.; Zarei, M.; Roichman, A.; Loftus, A.; Boutros, C.; Hue, J. J.; Naji, P.; Boyer, J. A.; Tahhan, S.; Gallagher, P.; Beegan, W.; Choi, J.; Lei, S.; Kim, C.; Rathore, M.; Nakazzi, F.; Shah, I.; Lebo, K.; Cheng, H.; Mudigonda, A.; Alibeckoff, S.; Ji, K.; Graor, H. J.; Miyagi, M.; Vaziri-Gohar, A.; Brunengraber, H.; Wang, R.; Lund, P.; Rothermel, L. D.; Rabinowitz, J. D.; Winter, J. M.
10.1101/2024.07.19.604377 — cancer biology — Posted on 2024-07-23
1537 SMYD5 is a ribosomal methyltransferase that catalyzes RPL40 lysine methylation to enhance translation output and promote hepatocellular carcinoma
Lan, F.; Miao, B.; Ge, L.; He, C.; Wang, X.; Li, X.; Wu, J.; Chen, K.; Wan, J.; Xing, S.; Ren, L.; Shi, Z.; Flores, N. M.; Cheng, J.; Mao, Y.; Xu, X.; Wang, R.; Liang, Z.; Mazur, P.; Cai, J.
10.1101/2024.07.21.604450 — cancer biology — Posted on 2024-07-23
1538 Deep Learning-based Modeling for Preclinical Drug Safety Assessment
Jaume, G.; de Brot, S.; Song, A. H.; Williamson, D. F. K.; Oldenburg, L.; Zhang, A.; Chen, R. J.; Asin, J.; Blatter, S.; Dettwiler, M.; Gopfert, C.; Grau Roma, L.; Soto, S.; Keller, S.; Rottenberg, S.; del-Pozo, J.; Pettit, R.; Le, L. P.; Mahmood, F.
10.1101/2024.07.20.604430 — bioinformatics — Posted on 2024-07-23
1539 Harnessing Dye-induced Photothermal Confinement in Lipid Membranes: A Path to NIR-modulated Artificial Synaptic Vesicles
Sarker, S. R.; Yamazaki, T.; Sou, K.; Takemura, I.; Kurita, Y.; Nomura, K.; Ichimura, M.; Suzuki, T.; Kai, A.; Araki, T.; Hattori, S.; Furuyama, T.; Chang, Y.-T.; Kiya, T.; Arai, S.
10.1101/2024.07.20.604262 — bioengineering — Posted on 2024-07-23
1542 Mitochondria affect photosynthesis through altered tissue levels of oxygen
Punkkinen, M.; Blokhina, O.; Peralta Ogorek, L. L.; Kim, M.; Fagerstedt, K. V.; Vierling, E.; Pedersen, O.; Shapiguzov, A.
10.1101/2024.07.19.604342 — plant biology — Posted on 2024-07-23
1543 The LYCOPENE EPSILON CYCLASE untranslated mRNA leader modulates carotenoid feedback and post-transcriptional regulation
Alagoz, Y.; Nayak, J.; Aryal, R.; Watkins, J.; Holland, S.; Tissue, D.; Pogson, B. J.; Cazzonelli, C. I.
10.1101/2024.07.19.604344 — plant biology — Posted on 2024-07-23
1544 TRAIL-induced cytokine production via NFKB2 pathway promotes neutrophil chemotaxis and immune suppression in triple negative breast cancers
Kundu, M.; Greer, Y. E.; Lobanov, A.; Ridnour, L.; Donahue, R. N.; Ng, Y.; Ratnayake, S.; Voeller, D.; Weltz, S.; Chen, Q.; Lockett, S. J.; Cam, M.; Meerzaman, D.; Wink, D. A.; Lipkowitz, S.
10.1101/2024.07.19.604341 — cancer biology — Posted on 2024-07-23
1547 A deep learning-based multiscale integration of spatial omics with tumor morphology.
Schmauch, B.; Herpin, L.; Olivier, A.; Duboudin, T.; Dubois, R.; Gillet, L.; Schiratti, J.-B.; Di Proietto, V.; Le Corre, D.; Bourgoin, A.; Taïeb, J.; Emile, J.-F.; Fridman, W. H.; Pronier, E.; Laurent-Puig, P.; Durand, E. Y.
10.1101/2024.07.22.604083 — bioinformatics — Posted on 2024-07-23
1548 FEHAT: Efficient, Large scale and Automated Heartbeat Detection in Medaka Fish Embryos.
Ferreira, M.; Stricker, S.; Fitzgerald, T. W.; Monahan, J.; Defranoux, F.; Watson, P.; Welz, B.; Hammouda, O.; Wittbrodt, J.; Birney, E.
10.1101/2024.07.21.604466 — bioinformatics — Posted on 2024-07-23
1549 3D printed bioelectronic scaffolds with soft tissue-like stiffness
Okafor, S. S.; Park, J.; Liu, T.; Goestenkors, A. P.; Alvarez, R. M.; Semar, B. A.; Yu, J. S.; O'Hare, C. P.; Montgomery, S. K.; Friedman, L. C.; Rutz, A. L.
10.1101/2024.07.19.604334 — bioengineering — Posted on 2024-07-23
1551 In-utero rescue of neurological dysfunction in a mouse model of Wiedemann-Steiner syndrome
Reynisdottir, T.; Anderson, K. J.; Brinn, A.; Franklin, K.; Ouyang, J.; Snorradottir, A. O.; Lutz, C. M.; Zuberi, A. R.; DeLeon, V. B.; Bjornsson, H. T.
10.1101/2024.07.19.604339 — genetics — Posted on 2024-07-23
1552 Interactions between weather, ungulates and geese create opportunities for wood-pasture cycles
Kramer, K.; Cornelissen, P.; Groot Bruinderink, G. W. T. A.; Kuiters, L.; Lammertsma, D.; Vulink, J. T.; Van Wieren, S. E.; Prins, H. H. T.
10.1101/2024.07.19.604241 — ecology — Posted on 2024-07-23
1555 A Novel Whole Tissue Explant Model of Hidradenitis Suppurativa
Leboit, P. E.; Patel, D. U.; Cohen, J. N.; Moss, M. I.; Naik, H. B.; Yates, A. E.; Harris, H. W.; Klufas, D. M.; Kim, E. A.; Neuhaus, I. M.; Hansen, S. L.; Kyle, R. L.; Kelly, M.; Rosenblum, M. D.; Lowe, M. M.
10.1101/2024.07.19.603617 — immunology — Posted on 2024-07-23
1556 Neuro-immunology in a mouse model of anti-NMDAR encephalitis and assessment of treatment approaches
Maudes, E.; Planaguma, J.; Marmolejo, L.; Radosevic, M.; Serafim, A. B.; Aguilar, E.; Sindreu, C.; Landa, J.; Garcia-Serra, A.; Mannara, F.; Cunquero, M.; Smith, A.; Milano, C.; Peixoto-Moledo, P.; Guasp, M.; Ruiz-Garcia, R.; Gray, S. M.; Spatola, M.; Loza-Alvarez, P.; Sabater, L.; Matute, C.; Dalmau, J.
10.1101/2024.07.19.604240 — neuroscience — Posted on 2024-07-23
1557 Long-lived adult-born hippocampal neurons promote successful cognitive aging
Blin, N.; Charrier, V.; Farrugia, F.; Cartier, E.; Pacary, E.; Koehl, M.; Lois, C.; Lie, D. C.; Masachs, N.; Abrous, N.
10.1101/2024.07.19.604332 — neuroscience — Posted on 2024-07-23
1559 Return of intracranial beta oscillations and traveling waves with recovery from traumatic brain injury
Vaz, A. P.; Wathen, C.; Miranda, S.; Thomas, R.; Darlington, T.; Jabarkheel, R.; Tomlinson, S.; Arena, J.; Bond, K.; Salwi, S.; Ajmera, S.; Bachschmid-Romano, L.; Gugger, J.; Sandsmark, D.; Diaz-Arrastia, R.; Schuster, J.; Ramayya, A.; Cajigas, I.; Pesaran, B.; Chen, I.; Petrov, D.
10.1101/2024.07.19.604293 — neuroscience — Posted on 2024-07-23
1562 Systemic inflammation is a minor contributor to remnant cholesterol atherogenicity
Kraaijenhof, J. M.; Kerkvliet, M.; Nurmohamed, N. S.; Grefhorst, A.; Kroon, J.; Wareham, N. J.; Hovingh, G. K.; Stroes, E. S.; Boekholdt, S. M.; Reeskamp, L. F.
10.1101/2024.07.18.604203 — systems biology — Posted on 2024-07-23
1569 Extending the Acute Skin Response Spectrum to Include the Far-UVC
Gutierrez-Bayona, N. E.; Petersen, C.; Hashmi, R. H.; Buonanno, M.; Shuryak, I.; Ponnaiya, B.; Kleiman, N. J.; Brenner, D. J.; Welch, D.
10.1101/2024.07.19.604306 — biophysics — Posted on 2024-07-23
1572 Bone mineral density affects tumor growth by shaping microenvironmental heterogeneity
Whitman, M. A.; Mantri, M.; Spanos, E.; Estroff, L. A.; De Vlaminck, I.; Fischbach, C.
10.1101/2024.07.19.604333 — bioengineering — Posted on 2024-07-23
1574 Dads on duty: First account of nest sitting in barnacle ganders
Scheiber, I. B. R.; Slettenhaar, A. J.; Loonen, M. J. J. E.; de Jong, M. E.
10.1101/2024.07.19.604238 — animal behavior and cognition — Posted on 2024-07-23
1580 Design principles of small intestinal crypt maintenance
banjac, I.; Maimets, M.; Tsang, I.; Dioli, M.; Hansen, S.; Krizic, K.; Bressan, R.; Lovkvist, C.; Jensen, K.
10.1101/2024.07.19.604296 — cell biology — Posted on 2024-07-23
1582 Diversity and functional specialization of oyster immune cells uncovered by integrative single cell level investigations
De La Forest Divonne, S.; Pouzadoux, J.; Romatif, O.; Montagnani, C.; Mitta, G.; Destoumieux-Garzon, D.; Gourbal, B.; Charriere, G. M.; Vignal, E.
10.1101/2024.07.19.604245 — immunology — Posted on 2024-07-23
1583 PLAbDab-nano: a database of camelid and shark nanobodies from patents and literature
Gordon, G. L.; Greenshields-Watson, A. L.; Agarwal, P.; Wong, A.; Boyles, F.; Hummer, A.; Lujan Hernandez, A. G.; Deane, C. M.
10.1101/2024.07.19.604232 — immunology — Posted on 2024-07-23
1585 Structural diversity of mitochondria in the neuromuscular system across development
Bae, J. A.; Choi, M.-k.; Ahn, S.; Ko, G.; Choe, D. T.; Yim, H.; Nguyen, K. C. Q.; Hall, D. H.; Kim, J. S.; Lee, J.
10.1101/2024.07.19.604219 — neuroscience — Posted on 2024-07-23
1586 Adaptive Safety Coding in the Prefrontal Cortex
Tashjian, S. M.; Cussen, J.; Deng, W.; Zhang, B.; Mobbs, D.
10.1101/2024.07.19.604228 — neuroscience — Posted on 2024-07-23
1587 Olfactory cortical outputs recruit and shape distinct brain-wide spatiotemporal networks
Ma, T.; Wang, X.; Lin, X.; Wen, J.; Xie, L.; Cao, P.; Leong, A. T. L.; Wu, E. X.
10.1101/2024.07.19.604242 — neuroscience — Posted on 2024-07-23
1589 Power-law adaptation in the presynaptic vesicle cycle
Mikulasch, F. A.; Georgiev, S. V.; Rudelt, L.; Rizzoli, S.; Priesemann, V.
10.1101/2024.07.19.604253 — neuroscience — Posted on 2024-07-23
1590 Spiking neural network models of sound localisation via a massively collaborative process
Ghosh, M.; Habashy, K. G.; De Santis, F.; Fiers, T.; Ercelik, D. F.; Meszaros, B.; Friedenberger, Z.; Bena, G.; Hong, M.; Abubacar, U.; Byrne, R. T.; Riquelme, J. L.; Liu, Y. H.; Aizenbud, I.; Bicknell, B. A.; Bormuth, V.; Antonietti, A.; Goodman, D. F. M.
10.1101/2024.07.19.604252 — neuroscience — Posted on 2024-07-23
1591 Uncovering the Neural Correlates of the Urge-to-Blink: A Study Utilising Subjective Urge Ratings and Paradigm Free Mapping
Houlgreave, M. S.; Urunuela, E.; Caballero-Gaudes, C.; Gowland, P. A.; Dyke, K.; Brandt, V.; Mohammed, I.; Sanchez Panchuelo, R. M.; Jackson, S. R.
10.1101/2024.07.19.603913 — neuroscience — Posted on 2024-07-23
1594 Integration of multi-omics and deep phenotyping provides novel insights into multiple abiotic stress responses in potato
Zagorscak, M.; Abdelhakim, L.; Rodriguez-Granados, N. Y.; Siroka, J.; Ghatak, A.; Bleker, C.; Blejec, A.; Zrimec, J.; Novak, O.; Pencik, A.; Baebler, S.; Borroto, L. P.; Schuy, C.; Zupanic, A.; Afjehi-Sadat, L.; Wurzinger, B.; Weckwerth, W.; Pompe-Novak, M.; Knight, M. R.; Strnad, M.; Bachem, C. W.; Chaturvedi, P.; Sonnewald, S.; Sasidharan, R.; Panzarova, K.; Gruden, K.; Teige, M.
10.1101/2024.07.18.604140 — plant biology — Posted on 2024-07-23
1595 Polysaccharide breakdown products drive degradation-dispersal cycles of foraging bacteria through changes in metabolism and motility
Stubbusch, A. K. M.; Keegstra, J. M.; Schwartzman, J.; Pontrelli, S.; Clerc, E. E.; Charlton, S.; Stocker, R.; Magnabosco, C.; Schubert, O. T.; Ackermann, M.; D'Souza, G. G.
10.1101/2023.07.14.548877 — microbiology — Posted on 2024-07-23
1599 Methionine Restriction Reduces Lung Cancer Progression and Increases Chemotherapy Response
Naughton, K. J.; Song, X.; Childress, A. R.; Skaggs, E. M.; Byrd, A. L.; Gosser, C. M.; Esoe, D.-P.; DuCote, T. J.; Plaugher, D. R.; Lukyanchuk, A.; Goettl, R. A.; Liug, J.; Brainson, C. F.
10.1101/2024.06.25.599795 — cancer biology — Posted on 2024-07-23
1600 Genome-wide CRISPR screen identifies KEAP1 perturbation as a vulnerability of ARID1A-deficient cells
Fournier, L.-A.; Kalantari, F.; Wells, J. P.; Lee, J. S.; Trigo-Gonzalez, G.; Moksa, M. M.; Smith, T.; White, J.; Shanks, A.; Wang, L.; Su, E.; Wang, Y.; Huntsman, D. G.; Hirst, M.; Stirling, P. C.
10.1101/2023.11.14.566591 — cancer biology — Posted on 2024-07-23
1605 Longitudinal sequencing reveals polygenic andepistatic nature of genomic response to selection
Forsberg, S. K. G.; Melo, D.; Grenier, J.; Wolf, S.; Tang, M.; Henry, L.; Pallares, L. F.; Clark, A. G.; Ayroles, J. F.
10.1101/2024.07.22.604612 — evolutionary biology — Posted on 2024-07-23
1606 Insect metamorphosis is regulated differently between sexes by members of a microRNA cluster
Li, C.; Chan, K. K.; Nong, W.; Chen, S.; So, W. L.; Qu, Z.; Wu, H. W. C.; Yip, H. Y.; Chan, C. B.; Tobe, S. S.; Bendena, W.; Kai, Z. P.; Hui, J. H. l.
10.1101/2024.06.25.600558 — evolutionary biology — Posted on 2024-07-23
1609 Contribution of the neuron-specific ATP1A3 to embryonic spinal circuit emergence
Dinvaut, S.; Calvet, S.; Comte, J.-C.; Gury, R.; Pascual, O.; Andre, M.; Ferrigno, R.; Honnorat, J.; Moret, F.; Marcy, G.; Falk, J.; Castellani, V.
10.1101/2024.06.11.598491 — developmental biology — Posted on 2024-07-23
1611 mTOR activation induces endolysosomal remodeling and nonclassical secretion of IL-32 via exosomes in inflammatory reactive astrocytes
Leng, K.; Rooney, B.; McCarthy, F.; Xia, W.; Rose, I. V. L.; Bax, S.; Chin, M. Y.; Fathi, S.; Herrington, K. A.; Leonetti, M.; Kao, A. W.; Fancy, S. P. J.; Elias, J. E.; Kampmann, M.
10.1101/2021.09.11.459904 — cell biology — Posted on 2024-07-23
1613 Multiomics unveils extracellular vesicle-driven mechanisms of endothelial communication in human carotid atherosclerosis
Raju, S.; Turner, M. E.; Cao, C.; Abdul-Samad, M.; Punwasi, N.; Blaser, M. C.; Cahalane, R. M.; Botts, S. R. C.; Prajapati, K.; Patel, S.; Wu, R.; Gustafson, D.; Galant, N. J.; Fiddes, L.; Chemaly, M.; Hedin, U.; Matic, L.; Seidman, M.; Subasri, V.; Singh, S. A.; Aikawa, E.; Fish, J. E.; Howe, K. L.
10.1101/2024.06.21.599781 — cell biology — Posted on 2024-07-23
1616 Mobile Integrons Encode Phage Defence Systems
Kieffer, N.; Hipolito, A.; Blanco, P.; Delobelle, T.; Ortiz-Miravalles, L.; Ojeda, F. M.; Jove, T.; Jurenas, D.; Garcia-Quintanilla, M.; Domingo-Calap, P.; Escudero, J. A.
10.1101/2024.07.02.601719 — microbiology — Posted on 2024-07-23
1619 Ternary representation of contextual information along the CA1 transverse axis
Duan, Y.-L.; Hu, S.-Y.; Ge, X.-F.; Long, J.-L.; Deng, C.; Sun, Y.-M.; Li, C.-J.; Zhang, R.; Cai, X.; Lu, L.
10.1101/2024.06.06.597717 — neuroscience — Posted on 2024-07-23
1620 Anatomical and behavioral correlates of auditory perception in developmental dyslexia
Qi, T.; Mandelli, M. L.; Watson Pereira, C. L.; Wellman, E.; Bogley, R.; Licata, A. E.; Chang, E. F.; Oganian, Y.; Gorno-Tempini, M. L.
10.1101/2023.05.09.539936 — neuroscience — Posted on 2024-07-23
1621 Working Memory Gating in Obesity is Moderated by Striatal Dopaminergic Gene Variants
Herzog, N.; Hartmann, H.; Janssen, L. K.; Kanyamibwa, A.; Waltmann, M.; Kovacs, P.; Deserno, L.; Fallon, S.; Villringer, A.; Horstmann, A.
10.1101/2023.11.03.565528 — neuroscience — Posted on 2024-07-23
1623 Trends in Self-citation Rates in High-impact Neurology, Neuroscience, and Psychiatry Journals
Rosenblatt, M.; Mehta, S.; Peterson, H.; Dadashkarimi, J.; Rodriguez, R. X.; Foster, M. L.; Adkinson, B. D.; Liang, Q.; Kimble, V. M.; Ye, J.; McCusker, M. C.; Farruggia, M. C.; Rolison, M.; Westwater, M. L.; Jiang, R.; Noble, S.; Scheinost, D.
10.1101/2022.09.27.509533 — neuroscience — Posted on 2024-07-23
1625 GABA-ergic inhibition in human hMT+ predicts visuo-spatial intelligence mediated through the frontal cortex
Gao, Y.; Cai, Y.-C.; Liu, D.-Y.; Yu, J.; Wang, J.; Li, M.; Xu, B.; Wang, T.; Chen, G.; Northoff, G.; Bai, R.; Song, X.
10.1101/2024.03.20.585863 — neuroscience — Posted on 2024-07-23
1626 Male rats emit aversive 44-kHz ultrasonic vocalizations during prolonged Pavlovian fear conditioning
Olszynski, K. H.; Polowy, R.; Wardak, A. D.; Laska, I. A.; Grymanowska, A. W.; Pulawski, W.; Gawrys, O.; Kolinski, M.; Filipkowski, R. K.
10.1101/2023.04.06.535936 — neuroscience — Posted on 2024-07-23
1631 Image processing tools for petabyte-scale light sheet microscopy data
Ruan, X.; Mueller, M.; Liu, G.; Görlitz, F.; Fu, T.-M.; Milkie, D. E.; Lillvis, J. L.; Kuhn, A.; Chong, J. G.; Hong, J. L.; Herr, C. Y. A.; Hercule, W.; Nienhaus, M.; Killilea, A. N.; Betzig, E.; Upadhyayula, S.
10.1101/2023.12.31.573734 — bioinformatics — Posted on 2024-07-23
1632 Ribosomal Frameshifting Selectively Modulates the Assembly, Function, and Pharmacological Rescue of a Misfolded CFTR Variant
Carmody, P.; Roushar, F. J.; Tedman, A.; Wang, W.; Herwig, M.; Kim, M.; McDonald, E. F.; Noguera, K.; Wong-Roushar, J.; Poirier, J.-L.; Zelt, N.; Pockrass, B.; McKee, A. G.; Kuntz, C. P.; Raju, S. V.; Plate, L.; Penn, W. D.; Schlebach, J. P.
10.1101/2023.05.02.539166 — biochemistry — Posted on 2024-07-23
1634 Prevalent fast evolution of genes involved in heterochromatin functions
Lin, L.; Huang, Y.; McIntyre, J.; Chang, C.-H.; Colmenares, S. S.; Lee, G. Y. C.
10.1101/2024.03.03.583199 — evolutionary biology — Posted on 2024-07-23
1635 Periosteal skeletal stem cells can migrate into the bone marrow and support hematopoiesis after injury
Marchand, T.; Akinnola, K. E.; Takeishi, S.; Maryanovich, M.; Pinho, S.; Saint-Vanne, J.; Birbrair, A.; Lamy, T.; Tarte, K.; Frenette, P.; Gritsman, K.
10.1101/2023.01.12.523842 — cell biology — Posted on 2024-07-23
1641 Scorpio : Enhancing Embeddings to Improve Downstream Analysis of DNA sequences
Refahi, M.; Sokhansanj, B. A.; Mell, J. C.; Brown, J.; Yoo, H.; Hearne, G.; Rosen, G.
10.1101/2024.07.19.604359 — genomics — Posted on 2024-07-23
1642 Evolutionary genomics of the emergence of brown algae as key components of coastal ecosystems
Denoeud, F.; Godfroy, O.; Cruaud, C.; Heesch, S.; Nehr, Z.; Tadrent, N.; Couloux, A.; Brillet-Gueguen, L.; Delage, L.; Mckeown, D.; Motomura, T.; Sussfeld, D.; Fan, X.; Mazeas, L.; Terrapon, N.; Barrera-Redondo, J.; Petroll, R.; Reynes, L.; Choi, S.-W.; Jo, J.; Uthanumallian, K.; Bogaert, K.; Duc, C.; Ratchinski, P.; Lipinska, A.; Noel, B.; Murphy, E. A.; Lohr, M.; Khatei, A.; Hamon-Giraud, P.; Vieira, C.; Akerfors, S. S.; Akita, S.; Avia, K.; Badis, Y.; Barbeyron, T.; Belcour, A.; Berrabah, W.; Blanquart, S.; Bouguerba, A.; Bringloe, T. T.; Cattolico, R. A.; Cormier, A.; Cruz de Carvalho, M.
10.1101/2024.02.19.579948 — genomics — Posted on 2024-07-23
1645 Centennial recovery of recent human-disturbed forests
Rodriguez-Una, A.; Cruz-Alonso, V.; Lopez-Lopez, J. A.; Moreno-Mateos, D.
10.1101/2024.07.21.604432 — ecology — Posted on 2024-07-23
1648 MDC1 mediates Pellino recruitment to sites of DNA double-strand breaks
Torres Esteban, M.; Stewart, M. J.; Bragginton, E.; Jeanrenaud, A.; Smerdon, S. J.; Stucki, M.
10.1101/2024.07.20.604390 — cell biology — Posted on 2024-07-23
1649 Molecular architecture of glideosome and nuclear F-actin in Plasmodium falciparum
Prazak, V.; Vasishtan, D.; Grunewald, K.; Douglas, R. G.; Ferreira, J. L.
10.1101/2024.04.22.590301 — microbiology — Posted on 2024-07-23
1650 Antimicrobial Resistance in Diverse Urban Microbiomes: Uncovering Patterns and Predictive Markers
Toscan, R. B.; Subramanian, B.; Stomma, P.; Łabaj, P. P.; Lesinski, W.; Rudnicki, W.
10.1101/2024.03.08.584116 — microbiology — Posted on 2024-07-23
1653 Striosomes Target Nigral Dopamine-Containing Neurons via Direct-D1 and Indirect-D2 Pathways Paralleling Classic Direct-Indirect Basal Ganglia Systems
Lazaridis, I.; Crittenden, J. R.; Ahn, G.; Hirokane, K.; Yoshida, T.; Wickersham, I.; Mahar, A.; Skara, V.; Loftus, J. H.; Parvataneni, K.; Meletis, K.; Ting, J. T.; Hueske, E.; Matsushima, A.; Graybiel, A. M.
10.1101/2024.06.01.596922 — neuroscience — Posted on 2024-07-23
1654 Lateral inhibition in V1 controls neural & perceptual contrast sensitivity
Del Rosario, J.; Coletta, S.; Kim, S. H.; Mobille, Z.; Peelman, K.; Williams, B.; Otsuki, A. J.; Del Castillo Valerio, A.; Worden, K.; Blanpain, L. T.; Lovell, L.; Choi, H.; Haider, B.
10.1101/2023.11.10.566605 — neuroscience — Posted on 2024-07-23
1661 A transposable element insertion in IAA16 interrupts normal splicing and generates a novel dicamba resistance allele in Bassia scoparia
Montgomery, J. S.; Soni, N.; Marques Hill, S.; Morran, S.; Patterson, E.; Edwards, S.; Ratnayake, S.; Hung, Y.-H.; Pandesha, P. H.; Slotkin, R. K.; Dayan, F. E.; Gaines, T. A.
10.1101/2024.07.19.604363 — plant biology — Posted on 2024-07-23
1663 Using deep learning predictions reveals a large number of register errors in PDB deposits
Sanchez Rodriguez, F.; Simpkin, A. J.; Chojnowski, G.; Keegan, R.; Rigden, D. J.
10.1101/2024.07.19.604304 — bioinformatics — Posted on 2024-07-23
1664 CGPA: multi-context insights from the cancer gene prognosis atlas
Cao, B.; Yu, X.; Gonzalez, G.; Murthy, A. R.; Li, T.; Shen, Y.; Yao, S.; Conejo-Garcia, J. R.; Jiang, P.; Wang, X.
10.1101/2024.07.19.604345 — bioinformatics — Posted on 2024-07-23
1665 AI-driven Discovery of Morphomolecular Signatures in Toxicology
Jaume, G.; Peeters, T.; Song, A. H.; Pettit, R.; Williamson, D. F. K.; Oldenburg, L.; Vaidya, A.; De Brot, S.; Chen, R. J.; Thiran, J.-P.; Le, L. P.; Gerber, G.; Mahmood, F.
10.1101/2024.07.19.604355 — bioinformatics — Posted on 2024-07-23
1666 Strain Tracking with Uncertainty Quantification
Kim, Y.; Worby, C. J.; Acharya, S.; van Dijk, L. R.; Alfonsetti, D.; Gromko, Z. J.; Azimzadeh, P. N.; Dodson, K. W.; Gerber, G. K.; Hultgren, S. J.; Earl, A. M.; Berger, B.; Gibson, T. E.
10.1101/2023.01.25.525531 — bioinformatics — Posted on 2024-07-23
1667 Non-Invasive Quality Control of Organoid Cultures Using Mesofluidic CSTR Bioreactors and High-Content Imaging
Charles, S.; Jackson-Holmes, E.; Sun, G.; Zhou, Y.; Siciliano, B.; Niu, W.; Han, H.; Nikitina, A.; Kemp, M. L.; Wen, Z.; Lu, H.
10.1101/2024.07.19.604365 — bioengineering — Posted on 2024-07-23
1668 Hydrophilic/ Omniphobic droplet arrays for high-throughput and quantitative enzymology
Lee, B.; Sunden, F.; Miller, M.; Pak, B.; Krebber, A.; Lutz, S.; Fordyce, P. M.
10.1101/2024.07.19.604368 — bioengineering — Posted on 2024-07-23
1670 Parallel patterns of cognitive aging in marmosets and macaques
Vanderlip, C. R.; Jutras, M. L.; Asch, P. A.; Zhu, S. Y.; Lerma, M. N.; Buffalo, E. A.; Glavis-Bloom, C.
10.1101/2024.07.22.604411 — animal behavior and cognition — Posted on 2024-07-23
1671 Chromosomal genome assembly resolves drug resistance loci in the parasitic nematode Teladorsagia circumcincta
McIntyre, J.; Morrison, A.; Maitland, K.; Berger, D.; Price, D. R. G.; Dougan, S.; Grigoriadis, D.; Tracey, A.; Holroyd, N.; Bull, K.; Rose Vineer, H.; Glover, M. J.; Morgan, E. R.; Nisbet, A. J.; McNeilly, T.; Bartley, Y.; Sargison, N.; Bartley, D.; Berriman, M.; Cotton, J.; Devaney, E.; Laing, R.; Doyle, S. R.
10.1101/2024.07.22.603261 — genomics — Posted on 2024-07-23
1673 Evolution of fast-growing piscivorous herring in the young Baltic Sea
Goodall, J.; Pettersson, M. E.; Bergstrom, U.; Cocco, A. E.; Delling, B.; Heimbrand, Y.; Karlsson, M.; Larsson, J.; Waldetoft, H.; Wallberg, A.; Wennerstrom, L.; Andersson, L.
10.1101/2024.07.20.604447 — evolutionary biology — Posted on 2024-07-23
1675 CTCF-DEPENDENT INSULATION OF Hoxb13 AND THE HETEROCHRONIC CONTROL OF TAIL LENGTH
Lopez-Delisle, L.; Zakany, J.; Bochaton, C.; OSTEIL, P.; Mayran, A.; Darbellay, F.; Mascrez, B.; Rekaik, H.; Duboule, D.
10.1101/2024.07.20.604409 — developmental biology — Posted on 2024-07-23
1676 Sub-chronic elevation in ambient temperature drives alterations to the sperm epigenome and accelerates early embryonic development in mice
Trigg, N. A.; Schjenken, J. E.; Martin, J. H.; Skerrett-Byrne, D. A.; Smyth, S. P.; Bernstein, I. R.; Anderson, A. L.; Stanger, S. J.; Simpson, E. N. A.; Tomar, A.; Teperino, R.; Conine, C. C.; De Iuliis, G. N.; Roman, S. D.; Bromfield, E. G.; Dun, M. D.; Eamens, A. L.; Nixon, B.
10.1101/2024.07.22.604196 — cell biology — Posted on 2024-07-23
1679 Lung structural cell dynamics are altered by influenza virus infection experience leading to rapid immune protection following viral re-challenge
Worrell, J. C.; Hargrave, K. E.; Finney, G. E.; Hansell, C.; Cole, J. J.; Singh Niijar, J.; Morton, F. R.; Pingen, M.; Purnell, T.; Mitchelson, K.; Brennan, E.; Allan, J.; Ilia, G.; Herder, V.; Kennedy Dietrich, C.; Doncheva, Y.; Jamieson, N.; MacLeod, M. K.
10.1101/2024.07.20.604410 — immunology — Posted on 2024-07-23
1680 White matter tract crossing and bottleneck regions in the fetal brain
Calixto, C.; Soldatelli, M.; Li, B.; Pierotich, L.; Gholipour, A.; Warfield, S. K.; Karimi, D.
10.1101/2024.07.20.603804 — neuroscience — Posted on 2024-07-22
1682 Longitudinal sequencing reveals polygenic andepistatic nature of genomic response to selection
Forsberg, S. K. G.; Melo, D.; Grenier, J.; Wolf, S.; Tang, M.; Henry, L.; Pallares, L. F.; Clark, A. G.; Ayroles, J. F.
10.1101/2024.07.22.604612 — evolutionary biology — Posted on 2024-07-22
1685 STK19 drives Transcription-Coupled Repair by stimulating repair complex stability, Pol II ubiquitylation and TFIIH recruitment
Ramadhin, A. R.; Lee, S.-H.; Zhou, D.; Salmazo, A.; Gonzalo-Hansen, C.; van Sluis, M.; Blom, C. M. A.; Janssens, R. C.; Raams, A.; Dekkers, D. H. W.; Bezstarosti, K.; Slade, D.; Vermeulen, W.; Pines, A.; Demmers, J. A.; Bernecky, C.; Sixma, T. K.; Marteijn, J. A.
10.1101/2024.07.22.604556 — molecular biology — Posted on 2024-07-22
1690 Super-resolution imaging of proteins inside live mammalian cells with mLIVE-PAINT
Bhaskar, H.; Gidden, Z.; Virdi, G.; Kleinjan, D.-J.; Rosser, S. J.; Gandhi, S.; Regan, L.; Horrocks, M. H.
10.1101/2024.07.22.604574 — synthetic biology — Posted on 2024-07-22
1692 G-quadruplexes are a source of vulnerability in BRCA2 deficient granule cell progenitors and medulloblastoma
Keahi, D. L.; Sanders, M. A.; Paul, M. R.; Webster, A. L. H.; Fang, Y.; Wiley, T. F.; Shalaby, S.; Carroll, T. S.; Chandrasekharappa, S. C.; Sandoval-Garcia, C.; MacMillan, M. L.; Wagner, J. E.; Hatten, M. E.; Smogorzewska, A.
10.1101/2024.07.20.604431 — cancer biology — Posted on 2024-07-22
1693 Programmable Editing of Primary MicroRNA Switches Stem Cell Differentiation and Improves Tissue Regeneration
Truong, V. A.; Chang, Y.-H.; Tu, Y.; Nguyen, N. T. K.; Pham, N. N.; Chang, C.-W.; Chang, Y.-H.; Ngo, D. T. K.; Pham, D. H.; Tu, J.; Dang, Q. T.; Truong, V. A.; Hu, Y.-C.
10.1101/2024.07.19.604260 — bioengineering — Posted on 2024-07-22
1695 STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair
van den Heuvel, D.; Rodriguez-Martinez, M.; van der Meer, P. J.; Nieto Moreno, N.; Park, J.; Kim, H.-S.; van Schie, J. J.; Wondergem, A. P.; D'Souza, A.; Yakoub, G.; Herlihy, A.; Kashyap, K.; Boissiere, T.; Walker, J.; Mitter, R.; Apelt, K.; de Lint, K.; Kirdok, I.; Ljungman, M.; Wolthuis, R. M.; Cramer, P.; Scharer, O. D.; Kokic, G.; Svejstrup, J. Q.; Luijsterburg, M. S.
10.1101/2024.07.22.604575 — molecular biology — Posted on 2024-07-22
1698 Dual modes of DNA N6-methyladenine maintenance by distinct methyltransferase complexes
Wang, Y.; Nan, B.; Ye, F.; Zhang, Z.; Yang, W.; Pan, B.; Niu, J.; Ju, A.; Liu, Y.; Zhang, W.; Liu, Y.; Gao, S.
10.1101/2024.07.21.604504 — molecular biology — Posted on 2024-07-22
1699 Metabolomics profiling reveals association of fermented herbal feed additive, growth performance and gut microbiota in piglets
Xiao, R.; Wang, L.; Tang, Z.; Qian, X.; Wang, J.; Lian, Y.; Tang, J.; Xu, J.; Lin, Y.; Shi, B.; Xu, P.; Xiong, Q.
10.1101/2024.07.21.604508 — microbiology — Posted on 2024-07-22
1700 Unravelling Plankton Adaptation in Global Oceans through the Analysis of Lipidomes
Liu, W.; Henry, H. C.; Lipp, J. S.; Fredricks, H. F.; Van Mooy, B.; Hinrichs, K.-U.
10.1101/2024.07.22.604538 — microbiology — Posted on 2024-07-22
1702 Inhibition of Fusarium oxysporum growth in banana by silver nanoparticles: in vitro and in vivo assays
Mendoza, N. V.; Yanez, P.; Magdama, F.; Pacheco, R.; Vielma, J.; Vanegas, M. E.; Pestryakov, A.; Bogdanchikova, N.; Chong-Aguirre, P.
10.1101/2024.07.22.604513 — microbiology — Posted on 2024-07-22
1703 Iron limitation differentially affects viral replication in key marine microbes
Yung, C. C. M.; Kelly, R. L.; Kauffman, K. M.; Cunningham, B.; Zimmerman, A.; Worden, A.; John, S. G.
10.1101/2024.07.22.604475 — microbiology — Posted on 2024-07-22
1704 ASO-enhancement of TARDBP exitron splicing mitigates TDP-43 proteinopathies
Yamagishi, T.; Koide, S.; Toyama, G.; Washida, A.; Yamada, Y.; Hanyu, R.; Nadbitova, E.; Koike, Y. M.; Konno, T.; Ishihara, T.; Kato, T.; Onodera, O.; Sugai, A.
10.1101/2024.07.22.604579 — neuroscience — Posted on 2024-07-22
1708 Correlated spontaneous activity sets up multi-sensory integration in the developing higher-order cortex
Dwulet, J. M.; Zabouri, N.; Kirchner, J. H.; Wosniack, M. E.; Raspanti, A.; Kong, D.; Houwen, G. J.; Maldonado, P. P.; Lohmann, C.; Gjorgjieva, J.
10.1101/2024.07.19.603239 — neuroscience — Posted on 2024-07-22
1712 CytoNormPy enables a fast and scalable removal of batch effects in cytometry datasets.
Exner, T.; Hackert, N. S.; Leomazzi, L.; Van Gassen, S.; Saeys, Y.; Lorenz, H.-M.; Grieshaber-Bouyer, R.
10.1101/2024.07.19.604225 — bioinformatics — Posted on 2024-07-22
1714 A pan-cancer gamma delta T cell repertoire
Yu, X.; Song, L.; Cen, L.; Cao, B.; Tao, R.; Shen, Y.; Abate-Daga, D.; Rodriguez, P. C.; Conejo-Garcia, J. R.; Wang, X.
10.1101/2024.07.18.604205 — genomics — Posted on 2024-07-22
1715 Evaluation of false positive and false negative errors in targeted next generation sequencing
Moon, Y.; Kim, Y.-H.; Kim, J.-K.; Hong, C. H.; Kang, E.-K.; Choi, H. W.; Lee, D.-e.; Kim, T.-M.; Heo, S. G.; Han, N.; Hong, K.-M.
10.1101/2024.07.22.603478 — genomics — Posted on 2024-07-22
1719 Conserved signals orchestrate self-organization and symmetry breaking of bi-layered epithelia during development and regeneration
Journot, R. P.; Huyghe, M.; Barthelemy, A.; Couto-Moreira, H.; Sumbal, J.; Faraldo, M. M.; Dubail, M.; Fouillade, C.; Fre, S. P.
10.1101/2024.07.21.603898 — developmental biology — Posted on 2024-07-22
1720 How do we imagine a speech? A triple network model for situationally simulated inner speech
Gao, X.; Yang, J.; Li, C.; Guo, X.; Wang, Y.; Qu, Z.; Li, W.; Liu, J.; Li, Z.; Li, W.; Hu, Z.; Li, J.; Huang, Y.; Chen, J.; Wen, H.; Zhao, Z.; Kaiser, D.; Wei, T.; Yuan, B.
10.1101/2024.07.18.604038 — neuroscience — Posted on 2024-07-22
1722 DREAMER: Exploring Common Mechanisms of Adverse Drug Reactions and Disease Phenotypes through Network-Based Analysis
Firoozbakht, F.; Elkjaer, M. L.; Handy, D.; Wang, R.; Chervontseva, Z.; Rarey, M.; Loscalzo, J.; Baumbach, J.; Tsoy, O.
10.1101/2024.07.20.602911 — systems biology — Posted on 2024-07-22
1724 The guardians of mitochondrial dynamics: a novel role for intermediate filament proteins
Hemel, I. M.; Steen, C.; Denil, S. L.; Ertaylan, G.; Kutmon, M.; Adriaens, M.; Gerards, M.
10.1101/2024.07.19.604282 — systems biology — Posted on 2024-07-22
1728 Network-based investigation of petroleum hydrocarbons-induced ecotoxicological effects and their risk assessment
Sahoo, A. K.; Madgaonkar, S. R.; Chivukula, N.; Karthikeyan, P.; Ramesh, K.; Marigoudar, S. R.; Sharma, K. V.; Samal, A.
10.1101/2024.07.18.604159 — pharmacology and toxicology — Posted on 2024-07-22
1730 γ-aminobutyric acid receptor B signaling drives glioblastoma in females in an immune-dependent manner
Pathak, A.; Palasalava, S.; Knott, M. V.; Colon, B.; Ciervo, E.; Zhou, Y.; Mitchell, J.; Pumar, O. T.; Wong, H. K. A.; Zhang, L.; Susic, N.; Shah, K. H.; Kay, K.; Chin, D.; Johnson, S.; Cheng, F.; Lyssiotis, C. A.; Watson, D. C.; Ceccarelli, M.; Shah, A.; Wahl, D.; Lathia, J.; Bayik, D.
10.1101/2024.07.18.603996 — cancer biology — Posted on 2024-07-22
1731 Ru(II)-Photoactive Agents for Targeting ER Stress and Immunogenic Cell Death
Denison, M.; Ullrich, A.; Herroon, M.; Mecca, S.; Turro, C.; PODGORSKI, I.; Gibson, H. M.; Kodanko, J. J.
10.1101/2024.07.18.604104 — cancer biology — Posted on 2024-07-22
1736 Ex vivo model of breast cancer cell invasion in live lymph node tissue
Morgaenko, K.; Arneja, A.; Ball, A. G.; Putelo, A. M.; Munson, J. M.; Rutkowski, M. R.; Pompano, R. R.
10.1101/2024.07.18.601753 — bioengineering — Posted on 2024-07-22
1737 Tunable bicontinuous macroporous cell culture scaffolds via kinetically controlled phase separation
Dudaryeva, O. Y.; Cousin, L.; Krajnovic, L.; Groebli, G.; Sapkota, V.; Ritter, L.; Deshmukh, D.; Style, R. W.; Levato, R.; Labouesse, C.; Tibbitt, M. W.
10.1101/2024.07.18.604180 — bioengineering — Posted on 2024-07-22
1740 Waves of Colonization and Gene Flow in a Great Speciator
Gyllenhaal, E. F.; Brady, S. S.; DeCicco, L. H.; Naikatini, A.; Hime, P. M.; Manthey, J. D.; Kelly, J. K.; Moyle, R. G.; Andersen, M. J.
10.1101/2024.07.18.603796 — evolutionary biology — Posted on 2024-07-22
1745 Effectiveness and equity of vaccination strategies against Rift Valley fever in a heterogeneous landscape
Tennant, W. S. D.; Cardinale, E.; Moutroifi, Y.; Spencer, S. E.; Charafouddine, O.; Tildesley, M. J.; Metras, R.
10.1101/2024.07.18.604096 — ecology — Posted on 2024-07-22
1747 Keeping common species common: the role of future climate refugee in species conservation
Serafini, C.; Santostasi, N. L.; Canestrelli, D.; Ficetola, G. F.; Maiorano, L.
10.1101/2024.07.19.602245 — ecology — Posted on 2024-07-22
1748 Modelling genetic risk of β-cell dysfunction in human induced pluripotent stem cells from patients carrying the MTNR1B risk variant.
Singh, T.; Kalamajski, S.; Cunha, J. P. M. C. M.; Hladkou, S.; Roberts, F.; Gheibi, S.; Soltanian, A.; Yektay Farahmand, K.; Ekstrom, O.; Mamidi, A.; Franks, P. W.; Rosengren, A.; Semb, H.; Mulder, H.; Fex, M.
10.1101/2024.07.19.603674 — cell biology — Posted on 2024-07-22
1752 NLRP1B allele 2 does not respond to Val-boro-Pro (VbP) in the intestinal epithelium
Mazzone, R. J.; Winsor, N. J.; Li, L. Y.; Barry, K. T.; Ranger, A.; Goyal, S.; Meade, J. J.; Bruce, J.; Philpott, D.; Girardin, S. E.
10.1101/2024.07.18.604161 — immunology — Posted on 2024-07-22
1753 Bona fide cytotoxic iNKT cells with superior antitumour responses identified in mice and humans
de Amat Herbozo, C.; Wong, S. W.; Kuypers, M.; Ilango, G.; Liu, Z.; Matthews, J. A.; Nguyen, A.; Veillette, A.; Gommerman, J. L.; Baranek, T.; Crome, S. Q.; Tsao, M. S.; Sacher, A. G.; Paget, C.; Mallevaey, T.
10.1101/2024.07.18.603987 — immunology — Posted on 2024-07-22
1754 Oestrogen influences B cell class-switching in individuals with an XX sex chromosome complement
Peckham, H.; Radziszewska, A.; de Gruijter, N. M.; Restuadi, R.; Kartawinata, M.; Robinson, G. A.; Martin-Gutierrez, L.; Deakin, C. T.; Wedderburn, L. R.; Jury, E. C.; Butler, G.; Rosser, E. C.; Ciurtin, C.
10.1101/2024.07.18.604160 — immunology — Posted on 2024-07-22
1756 TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism
Feiten, A. F.; Dahm, K.; van Lengerich, B.; Suh, J. H.; Reifschneider, A.; Wefers, B.; Bartos, L. M.; Wind-Mark, K.; Schlepckow, K.; Ulas, T.; De-Domenico, E.; Becker, M.; Khalin, I.; Davis, S. S.; Wurst, W.; Plesnila, N.; Neher, J. J.; Brendel, M.; Lewcock, J. W.; Di Paolo, G.; Capell, A.; Monroe, K. M.; Schultze, J. L.; Haass, C.
10.1101/2024.07.18.604115 — neuroscience — Posted on 2024-07-22
1757 Precuneus activity during retrieval is positively associated with amyloid burden in cognitively normal older APOE4 carriers
Fischer, L.; Molloy, E. N.; Pichet Binette, A.; Vockert, N.; Marquardt, J.; Pacha Pilar, A.; Kreissl, M. C.; Remz, J.; Poirier, J.; Rajah, M. N.; Villeneuve, S.; PREVENT-AD Research Group, ; Maass, A.
10.1101/2024.07.18.604145 — neuroscience — Posted on 2024-07-22
1759 Freestanding rGO electrodes with tunable porous structures for improved neural recording
Dong, M.; Yang, J.; Zhen, F.; Du, Y.; Ding, S.; Yu, A.; Zou, R.; Qiu, L.; Guo, Z.; Coleman, H. A.; Parkington, H. C.; Fallon, J. B.; Forsythe, J. S.; Liu, M.
10.1101/2024.07.18.603459 — neuroscience — Posted on 2024-07-22
1760 ARGX-119, a therapeutic agonist antibody targeting MuSK
Vanhauwaert, R.; Oury, J.; Vankerckhoven, B.; Steyaert, C.; Jensen, S. M.; Vergoossen, D. L. E.; Kneip, C.; Santana, L.; Lim, J. L.; Plomp, J. J.; Augustinus, R.; Koide, S.; Blanchetot, C.; Ulrichts, P.; Huijbers, M. G.; Silence, K.; Burden, S. J.
10.1101/2024.07.18.604166 — neuroscience — Posted on 2024-07-22
1761 Circulating Myeloid-Derived Suppressor Cell load and disease severity are associated to an enhanced oligodendroglial production in a murine model of multiple sclerosis
Serrano-Regal, M. P.; Camacho-Toledano, C.; Alonso-Garcia, I.; Ortega, M. C.; Machin-Diaz, I.; Lebron-Galan, R.; Garcia-Arocha, J.; Calahorra, L.; Clemente, D.
10.1101/2024.07.18.604171 — neuroscience — Posted on 2024-07-22
1762 Multi-Omic Analysis Reveals Lipid Dysregulation Associated with Mitochondrial Dysfunction in Parkinson's Disease Brain
Hallqvist, J.; Toomey, C. E.; Pinto, R.; Wernick, A.; Shahrani, M.; Heales, S.; Eaton, S.; Mills, K.; Gandhi, S.; Heywood, W. E.
10.1101/2024.07.18.604051 — neuroscience — Posted on 2024-07-22
1763 Inhibition of nitric oxide synthase transforms carotid occlusion-mediated benign oligemia into de novo large cerebral infarction
Kim, H.; Chung, J.; Kang, J. W.; Schellingerhout, D.; Lee, S. J.; Jang, H. J.; Park, I.; Kim, T.; Gwak, D.-S.; Lee, J. S.; Hong, S.-H.; Je, K.-H.; Bae, H.-J.; Sung, J.; Lo, E. H.; Faber, J.; Ayata, C.; Kim, D.-E.
10.1101/2024.07.18.604214 — neuroscience — Posted on 2024-07-22
1764 Deep Neural Networks to Register and Annotate the Cells of the C. elegans Nervous System
Atanas, A. A.; Lu, A. K.-Y.; Kim, J.; Baskoylu, S.; Kang, D.; Kramer, T. S.; Bueno, E.; Wan, F. K.; Flavell, S. W.
10.1101/2024.07.18.601886 — neuroscience — Posted on 2024-07-22
1765 Automated preparation of plasma lipids, metabolites, and proteins for LC/MS-based analysis of a high-fat diet in mice
Vu, N.; Maile, T. M.; Gullapudi, S.; Gaun, A.; Seitzer, P.; O'Brien, J. J.; Hackett, S. R.; Zavala-Solorio, J.; McAllister, F. E.; Kolumam, G.; Keyser, R.; Bennett, B. D.
10.1101/2024.07.18.602745 — physiology — Posted on 2024-07-22
1767 A mouse model of cardiac AL amyloidosis unveils mechanisms of tissue accumulation and toxicity of amyloid fibrils
Martinez-Rivas, G.; Ayala, M. V.; Bender, S.; Codo, G. R.; Swiderska, K. W.; Lampis, A.; Pedroza, L.; Merdanovic, M.; Sicard, P.; Pinault, E.; Richard, L.; Lavatelli, F.; Canetti, D.; Rinsant, A.; Sihem, K.; Ory, C.; Oblet, C.; Pollet, J.; Naser, E.; Carpinteiro, A.; Roussel, M.; Javaugue, V.; Jaccard, A.; Bonaud, A.; Delpy, L.; Ehrmann, M.; Bridoux, F.; Sirac, C.
10.1101/2024.07.18.604040 — pathology — Posted on 2024-07-22
1768 Sex-Specific Changes in Cardiac Function and Electrophysiology During Progression of Adenine-Induced Chronic Kidney Disease in Mice
Dargam, V.; Sanchez, A.; Kolengaden, A.; Perez, Y.; Arias, R.; Valentin Cabrera, A. M.; Chaparro, D.; Tarafa, C.; Coba, A.; Yapaolo, N.; Todd, E. A.; Williams, M. M.; Shehadeh, L. A.; Hutcheson, J. D.
10.1101/2024.07.18.604201 — pathology — Posted on 2024-07-22
1769 Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality
Cunningham, C. E.; Vizeacoumar, F. S.; Zhang, Y.; Kyrylenko, L.; Gao, P.; Maranda, V.; Dong, H.; Price, J. D.; Ganapathysamy, A.; Hari, R.; Denomy, C.; Both, S.; Wagner, K.; Wu, Y.; Khan, F.; Mosley, S.; Chen, A.; Katrii, T.; Zoller, B. G.; Rajamanickam, K.; Walke, P.; Gong, L.; Patel, H.; Lazell-Wright, M.; Morejon Morales, A.; Bhanumathy, K. K.; Elhasasna, H.; Dahiya, R.; Abuhussein, O.; Dmitriev, A.; Freywald, T.; Prando Munhoz, E.; Krishnan, A.; Ruppin, E.; Lee, J. S.; Rox, K.; Toosi, B.; Koebel, M.; Kinloch, M.; Hopkins, L.; Lee, C. H.; Datla, R.; Yadav, S.; Wu, Y.; Baker, K.; Empting, M.
10.1101/2024.07.18.603978 — cancer biology — Posted on 2024-07-22
1770 Vortex light field microscopy: 3D spectral single-molecule imaging with a twist
Zhang, B.; Daly, S.; Zhu, C.; Lenz, M. O.; Weiss, L. E.; Needham, L.-M.; Peters, R.; Lee, S.; O'Holleran, K.
10.1101/2024.07.18.604091 — biophysics — Posted on 2024-07-22
1775 A high-resolution model of gene expression during Gossypium hirsutum (cotton) fiber development
Grover, C. E.; Jareczek, J. J.; Swaminathan, S.; Lee, Y.; Howell, A. H.; Rani, H.; Arick, M. A.; Leach, A. G.; Miller, E. R.; Yang, P.; Hu, G.; Xiong, X.; Mallery, E. L.; Peterson, D. G.; Xie, J.; Haigler, C. H.; Zabotina, O. A.; Szymanski, D. B.; Wendel, J. F.
10.1101/2024.07.20.604417 — cell biology — Posted on 2024-07-22
1776 Secreted exosomes induce filopodia formation
McAtee, C.; Patel, M. R.; Hoshino, D.; Sung, B. H.; von Lersner, A. K.; Shi, M.; Hong, N. H.; Young, A.; Krystofiak, E.; Zijlstra, A.; Weaver, A. M.
10.1101/2024.07.20.604139 — cell biology — Posted on 2024-07-22
1777 Classification of human actin pathological variants using C. elegans CRISPR-generated models
Hecquet, T.; Arbogast, N.; Suhner, D.; Goetz, A.; Amann, G.; Yürekli, S.; Marangoni, F.; Greve, J. N.; Di Donato, N.; Reymann, A.-C.
10.1101/2024.07.22.604239 — cell biology — Posted on 2024-07-22
1779 Cell State-Specific Cytoplasmic Material Properties Control Spindle Architecture and Scaling
Kletter, T.; Munoz, O.; Reusch, S.; Biswas, A.; Halavatyi, A.; Neumann, B.; Kuropka, B.; Zaburdaev, V.; Reber, S.
10.1101/2024.07.22.604615 — cell biology — Posted on 2024-07-22
1781 Bone pain in Fibrous dysplasia does not rely on aberrant sensory nerve sprouting or neuroma formation
Palmisano, B.; Tavanti, C.; Farinacci, G.; Gosti, G.; Leonetti, M.; Donsante, S.; Giannicola, G.; Appelman-Dijkstra, N.; Corsi, A.; Ippolito, E.; Riminucci, M.
10.1101/2024.07.18.603554 — pathology — Posted on 2024-07-22
1782 An Alternatively Spliced Gain-of-Function NT5C2 Isoform Contributes to Chemoresistance in Acute Lymphoblastic Leukemia
Diz, M. T.; Reglero, C.; Falkenstein, C. D.; Castro, A.; Hayer, K. E.; Radens, C.; Quesnel-Vallieres, M.; Ang, Z.; Sehgal, P.; Li, M. M.; Barash, Y.; Tasian, S. K.; Ferrando, A.; Thomas-Tikhonenko, A.
10.1101/2023.09.14.557413 — cancer biology — Posted on 2024-07-22
1788 Advancing the Indian Cattle Pangenome: Characterizing Non-Reference Sequences in Bos indicus
Azam, S.; Sahu, A.; Pandey, N. K.; Neupane, M.; Tassel, C. P. V.; Rosen, B. D.; Gandham, R. K.; Rath, S. N.; Majumdar, S. S.
10.1101/2024.07.18.604025 — genomics — Posted on 2024-07-22
1789 The domesticated transposon protein L1TD1 associates with its ancestor L1 ORF1p to promote LINE-1 retrotransposition
Kavaklioglu, G.; Podhornik, A.; Vcelkova, T.; Marjanovic, J.; Beck, M. A.; Phan-Canh, T.; Mair, T.; Miccolo, C.; Drino, A.; Doni, M.; Egger, G.; Chiocca, S.; Modic, M.; Seiser, C.
10.1101/2024.02.01.577722 — genetics — Posted on 2024-07-22
1795 Aeromonas hydrophila CobQ is a new type of NAD+- and Zn2+-independent protein lysine deacetylase
Wang, Y.; Wang, G.; Zhang, L.; Cai, Q.; Lin, M.; Huang, D.; Xie, Y.; Lin, W.; Lin, X.
10.1101/2024.03.22.586220 — microbiology — Posted on 2024-07-22
1805 Intravenous BCG induces a more potent airway and lung immune response than intradermal BCG in SIV-infected macaques
Jauro, S.; Larson, E. C.; Gleim, J. L.; Wahlberg, B. M.; Rodgers, M. A.; Chehab, J. C.; Lopez-Velazques, A. E.; Ameel, C. L.; Tomko, J. A.; Sakal, J. L.; DeMarco, T.; Jake Borish, H.; Maiello, P.; Potter, E. L.; Roederer, M.; Lin, P. L.; Flynn, J. L.; Scanga, C. A.
10.1101/2024.07.17.603921 — immunology — Posted on 2024-07-22
1807 Normative trajectories of R1, R2* and magnetic susceptibility in basal ganglia on healthy ageing
Chan, K.-S.; Zwiers, M. P.; Jansen, M. G.; Oosterman, J. M.; Norris, D. G.; Beckmann, C. F.; Marques, J. P.
10.1101/2024.07.17.603922 — neuroscience — Posted on 2024-07-22
1810 Tensor Kernel Learning for Classification of Alzheimer's Conditions using Multimodal Data
Vu, T. D.; Le, T. T.; Pham, T. M.; Nguyen, T. L.; Merai, K. A.; Adel, M.; Nguyen, D. V.; Nguyen, T. T.; Dinh, L. D.; Chen, O. Y.
10.1101/2024.07.17.603875 — neuroscience — Posted on 2024-07-22
1812 Blocking the ability of huntingtin to bind membranes: a therapeutic strategy for Huntingtons disease
Siriwardhana, C.; Adegbuyiro, A.; Sedighi, F.; Stonebraker, A. R.; Leonard, S.; Beasley, M.; Skeens, A.; Mertz, B.; Geldenhuys, W. J.; Legleiter, J.
10.1101/2024.07.17.603089 — biophysics — Posted on 2024-07-22
1813 AliMarko: A Novel Tool for Eukaryotic Virus Identification Using Expert-Guided Approach
Popov, N.; Evdokimova, A.; Sonets, I.; Panova, V.; Molchanova, M.; Korneenko, E.; Manolov, A.; Ilina, E.
10.1101/2024.07.19.603887 — bioinformatics — Posted on 2024-07-22
1817 Effects of copepod chemical cues on intra- and extracellular toxins in two species of Dinophysis
Pourdanandeh, M.; Sechet, V.; Carpentier, L.; Reveillon, D.; Herve, F.; Hubert, C.; Hess, P.; Selander, E.
10.1101/2024.07.17.603891 — ecology — Posted on 2024-07-22
1819 The distribution of the hemlock woolly adelgid in Canada.
MacQuarrie, C. J. K.; Gray, M.; Bullas-Appleton, E.; Kimoto, T.; Mielewczyk, N.; Neville, R.; Ogden, J. B.; Fidgen, J. G.; Turgeon, J. J.
10.1101/2024.07.18.604084 — ecology — Posted on 2024-07-22
1822 SpeSpeNet: An interactive and user-friendly tool to create and explore microbial correlation networks
van Eijnatten, A. L.; van Zon, L.; Manousou, E.; Bikineeva, M.; Wubs, J.; van der Putten, W.; Morriën, E.; Dutilh, B. E.; Snoek, B. L.
10.1101/2024.07.17.603889 — ecology — Posted on 2024-07-22
1825 Spike inference from mouse spinal cord calcium imaging data
Rupprecht, P.; Fan, W.; Sullivan, S. J.; Helmchen, F.; Sdrulla, A.
10.1101/2024.07.17.603957 — neuroscience — Posted on 2024-07-22
1826 An enhancer-AAV toolbox to target and manipulate distinct interneuron subtypes
Furlanis, E.; Dai, M.; Leyva Garcia, B.; Vergara, J.; Pereira, A.; Pelkey, K.; Tran, T.; Gorissen, B. L.; Vlacho, A.; Hairston, A.; Huang, S.; Dwivedi, D.; Du, S.; Wills, S.; McMahon, J.; Lee, A. T.; Chang, E. F.; Razzaq, T.; Qazi, A.; Vargish, G.; Yuan, X.; Caccavano, A.; Hunt, S.; Chittajallu, R.; McLean, N.; Hewit, L.; Paranzino, E.; Rice, H.; Cummins, A. C.; Plotnikova, A.; Mohanty, A.; Tangen, A. C.; Shin, J. H.; Azadi, R.; Eldridge, M. A. G.; Alvarez, V. A.; Averbeck, B. B.; Alyahyay, M.; Reyes Vallejo, T.; Soheib, M.; Vattino, L. G.; MacGregor, C. P.; Banks, E.; Olah, V. J.; Naskar, S.;
10.1101/2024.07.17.603924 — neuroscience — Posted on 2024-07-22
1828 PATJ regulates cell stress responses and vascular remodeling post-stroke
Zhang, M.; Jiang, W.; Arkelius, K.; Swanson, R. A.; Ma, D. K.; Singhal, N. S.
10.1101/2024.07.17.603777 — neuroscience — Posted on 2024-07-22
1829 A selective S-acyltransferase inhibitor suppresses tumor growth
Lee, J.-Y.; Dilones, S.; Maujean, T.; Asad, M.; Najar, M. A.; Auslander, N.; Brady, D. C.; Burslem, G. M.; Witze, E.
10.1101/2024.07.18.604152 — cancer biology — Posted on 2024-07-22
1831 WITHDRAWN: Anti-TNF-induced IL-27 modulates regulatory T cell responses in patients with IBD that respond to therapy
Sanches Peres, R.; Thomas, T.; Friedrich, M.; Pohin, M.; Pearson, C.; Ferreira, R.; Mann, E.; Trzupek, D.; Rich-Griffin, C.; Jainarayanan, A.; Jones, K.; Gu, Y.; Todd, J.; Uhlig, H.; Buckley, C.; Dendrou, C.; Travis, S.; Powrie, F.
10.1101/2022.11.21.517257 — immunology — Posted on 2024-07-22
1833 Structures of TGF-beta with betaglycan and the signaling receptors reveal the mechanism whereby betaglycan potentiates receptor complex assembly and signaling
Wieteska, L.; Taylor, A. B.; Punch, E.; Coleman, J. A.; Conway, I. O.; Lin, Y.-F.; Byeon, C.-H.; Hinck, C. S.; Krzysiak, T.; Ishima, R.; Lopez-Casillas, F.; Cherepanov, P.; Bernard, D. J.; Hill, C. S.; Hinck, A. P.
10.1101/2024.07.19.604101 — biophysics — Posted on 2024-07-22
1836 Amyloid fibril structures link CHCHD10 and CHCHD2 to neurodegeneration.
Lv, G.; Sayles, N. M.; Huang, Y.; Mancinelli, C. D.; McAvoy, K.; Shneider, N. A.; Manfredi, G.; Kawamata, H.; Eliezer, D.
10.1101/2024.07.18.604174 — biophysics — Posted on 2024-07-22
1838 The structure of a NEMO construct engineered for screening reveals novel determinants of inhibition
Kenedy, A. E.; Barczewski, A. H.; Arnoldy, C. R.; Pennington, J. P.; Tiernan, K. A.; Hidalgo, M. B.; Reilly, C. C.; Ragusa, M. J.; Grigoryan, G.; Mierke, D. F.; Pellegrini, M.
10.1101/2024.07.18.604176 — biophysics — Posted on 2024-07-22
1841 Endogenous and fluorescent sterols reveal the molecular basis for ligand selectivity of human sterol transporters
Depta, L.; Bryce-Rogers, H. P.; Dekker, N. J.; Bonke, A. W.; Camporese, N.; Qian, M.; Xu, Y.; Covey, D. F.; Laraia, L.
10.1101/2024.07.22.604041 — biochemistry — Posted on 2024-07-22
1843 Cell state and transcription factor modulation during extended ex vivo CD8+ T-cell expansion.
Lui, Y.; Jenkins, E.; Ng, E. Z. Q.; Kotowski, M.; Mullin, S. J.; Clarke, J.; Davis, S. J.; Santos, A. M.; Sharma, S.
10.1101/2024.07.17.603780 — immunology — Posted on 2024-07-22
1844 Necrosis drives susceptibility to Mycobacterium tuberculosis in POLG mtDNA mutator mice
Mabry, C. J.; Weindel, C. G.; Stranahan, L. W.; Martinez, E. L.; VanPortfliet, J. J.; West, P. L.; Patrick, K. L.; Watson, R. O.
10.1101/2024.07.17.603991 — immunology — Posted on 2024-07-22
1845 Single cell RNA-sequencing reveals GINIP-expressing neurons as the main targets of focused ultrasound
Brunet, E.; Parpaite, T.; Yoo, S.; Debieu, E.; Metwally, K.; Mensah, S.; Malapert, P.; Saurin, A.; Macherey, O.; Franceschini, E.; Moqrich, A.
10.1101/2024.07.17.604026 — neuroscience — Posted on 2024-07-22
1851 Intestinal serotonergic vagal signaling as a mediator of microbiota-induced hypertension
de Araujo, A.; Sree Kumar, H.; Yang, T.; Alviter Plata, A.; Dirr, E. W.; Bearss, N.; Baekey, D. M.; Miller, D. S.; Donertas-Ayaz, B.; Ahmari, N.; Singh, A.; Kalinoski, A. L.; Garrett, T.; Martyniuk, C. J.; de Lartigue, G.; Zubcevic, J.
10.1101/2024.07.17.603451 — physiology — Posted on 2024-07-22
1855 MENTOR: Multiplex Embedding of Networks for Team-Based Omics Research
Sullivan, K. A.; Miller, J. I.; Townsend, A.; Morgan, M.; Lane, M.; Pavicic, M.; Shah, M.; Cashman, M.; Jacobson, D. A.
10.1101/2024.07.17.603821 — bioinformatics — Posted on 2024-07-22
1857 Bioadhesive Hydrogel-Coupled and Miniaturized Ultrasound Transducer System for Long-Term, Wearable Neuromodulation
Tang, K. W. K.; Jeong, J.; Ju-Chun, H.; Yao, M.; Ding, H.; Wang, W.; Liu, X.; Pyatnitskiy, I.; He, W.; Moscoso-Barrera, W. D.; Lozano, A. R.; Artman, B.; Huh, H.; Wilson, P. S.; Wang, H.
10.1101/2024.07.17.603650 — bioengineering — Posted on 2024-07-22
1859 De Novo Design of Peptide Binders to Conformationally Diverse Targets with Contrastive Language Modeling
Bhat, S.; Palepu, K.; Hong, L.; Mao, J.; Ye, T.; Iyer, R.; Zhao, L.; Chen, T.; Vincoff, S.; Watson, R.; Wang, T.; Srijay, D.; Kavirayuni, V. S.; Kholina, K.; Goel, S.; Vure, P.; Desphande, A. H.; Soderling, S.; DeLisa, M.; Chatterjee, P.
10.1101/2023.06.26.546591 — bioengineering — Posted on 2024-07-22
1864 The N-degron pathway governs autophagy to promote thermotolerance in Arabidopsis
Kim, S. H.; Park, J. S.; Lee, M.-H.; Seo, J.; Kim, J.; Yang, W. S.; Park, J.; Yoo, K.; Choi, J.; Seo, J.-B.; Song, H. K.; Park, O. K.
10.1101/2024.07.17.604022 — plant biology — Posted on 2024-07-22
1865 Multiomics-based assessment of the impact of airflow on diverse plant callus cultures
Kim, J.-S.; Sato, M.; Kojima, M.; Asrori, M. I.; Uehara-Yamaguchi, Y.; Takebayashi, Y.; Do, T. N.; Do, T. Y.; Thi, K. O. N.; Sakakibara, H.; Mochida, K.; Ogita, S.; Hirai, M. Y.
10.1101/2024.07.17.604000 — plant biology — Posted on 2024-07-22
1869 Early Steps of Protein Disaggregation by Hsp70 Chaperone and Class B J-Domain Proteins are Shaped by Hsp110
Sztangierska, W.; Wyszkowski, H.; Pokornowska, M.; Kochanowicz, K.; Rychlowski, M.; Liberek, K.; Klosowska, A.
10.1101/2023.10.31.564973 — biochemistry — Posted on 2024-07-22
1870 BETA-HYDROXYBUTYRATE COUNTERACTS THE DELETERIOUS EFFECTS OF A SATURATED HIGH-FAT DIET ON SYNAPTIC AMPA RECEPTORS AND COGNITIVE PERFORMANCE
Rojas, R.; Grinan-Ferre, C.; Castellanos, A.; Griego, E.; Martinez, M.; Navarro-Lopez, J. d. D.; Jimenez-Diaz, L.; Rodriguez-Alvarez, J.; Soto del Cerro, D.; Castillo, P. E.; Pallas, M.; Fado, R.; Casals, N.
10.1101/2024.01.23.576931 — neuroscience — Posted on 2024-07-22
1871 Sequential replacement of PSD95 subunits in postsynaptic supercomplexes is slowest in the cortex.
Morris, K.; Bulovaite, E.; Kaizuka, T.; Schnorrenberg, S.; Adams, C.; Komiyama, N.; Mendive-Tapia, L.; Grant, S. G. N.; Horrocks, M. H.
10.1101/2023.07.13.548866 — neuroscience — Posted on 2024-07-22
1872 The value of livestock abortion surveillance in Tanzania: identifying disease priorities and informing interventions
Lankester, F.; Kibona, T. J.; Allan, K. J.; de Glanville, W.; Buza, J. J.; Katzer, F.; Halliday, J. E.; Mmbaga, B. T.; Wheelhouse, N.; Innes, E. A.; Thomas, K.; Nyasebwa, O. M.; Swai, E.; Claxton, J. R.; Cleaveland, S.
10.1101/2024.01.07.574517 — zoology — Posted on 2024-07-22
1874 Evolution of the CRISPR-Cas9 defence system in Mycoplasma gallisepticum following colonization of a novel bird host
Ipoutcha, T.; Tsarmpopoulos, I.; Gourgues, G.; Baby, V.; Dubos, P.; Hill, G. E.; Arfi, Y.; Lartigue, C.; Thebault, P.; Bonneaud, C.; Sirand-Pugnet, P.
10.1101/2023.03.14.532377 — microbiology — Posted on 2024-07-22
1876 Reduced discrimination between signals of danger and safety but not overgeneralization is linked to exposure to childhood adversity in healthy adults
Klingelhoefer-Jens, M.; Hutterer, K.; Schiele, M. A.; Leehr, E. J.; Schuemann, D.; Rosenkranz, K.; Boehnlein, J.; Repple, J.; Deckert, J.; Domschke, K.; Dannlowski, U.; Lueken, U.; Reif, A.; Romanos, M.; Zwanzger, P.; Pauli, P.; Gamer, M.; Lonsdorf, T. B.
10.1101/2023.09.26.559474 — neuroscience — Posted on 2024-07-22
1877 Multi-way modelling of oral microbial dynamics and host-microbiome interactions during induced gingivitis
van der Ploeg, G. R.; Brandt, B.; Keijser, B.; van der Veen, M.; Volgenant, C.; Zaura, E.; Smilde, A.; Westerhuis, J.; Heintz-Buschart, A.
10.1101/2024.03.18.585469 — systems biology — Posted on 2024-07-22
1880 ZIP13 regulates lipid metabolism by changing intracellular iron and zinc balance
Fukunaka, A.; Tanaka, G.; Kimura, T.; Hengphasatporn, K.; Saito, D.; Shigeta, M.; Shibata, H.; Ichinose, T.; Abe, I.; Shimura, M.; Sato, T.; Nakagawa, Y.; Horii, T.; Hatada, I.; Kajimura, S.; Kiyonari, H.; Sakurai, H.; Shigeta, Y.; Watada, H.; Fukada, T.; Fujitani, Y.
10.1101/2024.07.03.601606 — cell biology — Posted on 2024-07-22
1881 Hierarchical structural organization in bioinspired peptide coacervate microdroplets
Lim, J.; Gudlur, S.; Buchanan, C.; Perrin, Q. M.; Boyd, H.; Moulin, M.; Iwase, H.; Porcar, L.; Cardenas, M.; Miserez, A.; Pervushin, K.
10.1101/2024.07.06.602323 — biochemistry — Posted on 2024-07-22
1882 Cohesin-mediated 3D contacts tune enhancer-promoter regulation
Guckelberger, P.; Doughty, B. R.; Munson, G.; Rao, S. S. P.; Tan, Y.; Cai, X. S.; Fulco, C. P.; Nasser, J.; Mualim, K. S.; Bergman, D. T.; Ray, J.; Jagoda, E.; Munger, C. J.; Gschwind, A. R.; Sheth, M. U.; Tan, A. S.; Pulido, S. G.; Mitra, N.; Weisz, D.; Shamim, M. S.; Durand, N. C.; Mahajan, R.; Khan, R.; Steinmetz, L. M.; Kanemaki, M. T.; Lander, E. S.; Meissner, A.; Aiden, E. L.; Engreitz, J. M.
10.1101/2024.07.12.603288 — molecular biology — Posted on 2024-07-22
1883 Ilamycin E and ilamycin F are dual inhibitors of ClpX and ClpC1 in mycobacteria
Gao, Y.; Fang, C.; Zhou, B.; Hameed, H. M. A.; Sun, C.; Tian, X.; He, J.; Han, X.; Zhang, H.; Li, J.; Ju, J.; Chen, X.; Zhong, N.; Ma, J.; Xiong, X.; Zhang, T.
10.1101/2024.02.24.581832 — microbiology — Posted on 2024-07-22
1884 Proteomic evidence of depression-associated astrocytic dysfunction in the human male olfactory bulb
Rahimian, R.; Perlman, K.; Fakhfouri, G.; Mpai, R.; Richard, V. R.; Hercher, C.; Penney, L.; Davoli, M. A.; Nagy, C.; Zahedi, R. P.; Borchers, C. H.; Giros, B.; Turecki, G.; Mechawar, N.
10.1101/2023.10.29.564604 — neuroscience — Posted on 2024-07-22
1886 Automated detection of Bornean white-bearded gibbon (Hylobates albibarbis) vocalisations using an open-source framework for deep learning
Owens, A. F.; Hockings, K. J.; Imron, M. A.; Madhusudhana, S.; Mariaty, ; Setia, T. M.; Sharma, M. D.; Soebagio, S. M.; Van Veen, F. J. F.; Erb, W. M.
10.1101/2024.04.15.589517 — ecology — Posted on 2024-07-21
1887 Super-enhancer-driven CACNA2D2 is an EWSR1::WT1 signature gene encoding a diagnostic marker for desmoplastic small round cell tumor (DSRCT)
Geyer, F. H.; Ritter, A.; Kinn-Gurzo, S.; Faehling, T.; Li, J.; Jarosch, A.; Ngo, C.; Vinca, E.; Aljakouch, K.; Orynbek, A.; Ohmura, S.; Kirchner, T.; Imle, R.; Romero-Perez, L.; Bertram, S.; de Alava, E.; Postel-Vilnay, S.; Banito, A.; Sill, M.; Versleijen-Jonkers, Y. M. H.; Mayer, B. F. B.; Ebinger, M.; Sparber-Sauer, M.; Stegmaier, S.; Baumhoer, D.; Hartmann, W.; Krijgsveld, J.; Horst, D.; Delattre, O.; Grohar, P. J.; Gruenewald, T. G. P.; Cidre-Aranaz, F.
10.1101/2024.07.17.603708 — cancer biology — Posted on 2024-07-21
1888 The inhibition of three distinct signaling pathways eliminates the oncogenic Tribbles homolog 2 from melanoma cells
Mayoral-Varo, V.; Orea-Soufi, A.; Jimenez, L.; Santos, B.; Serrao, G.; Jociles, M.; Obeso, S.; Ferreira, B.; Link, W.
10.1101/2024.07.17.603886 — cancer biology — Posted on 2024-07-21
1891 Deep Profiling of Plasma Proteoforms with Engineered Nanoparticles for Top-down Proteomics
Huang, C.-F.; Hollas, M. A.; Sanchez, A.; Bhattacharya, M.; Ho, G.; Sundaresan, A.; Caldwell, M. A.; Zhao, X.; Benz, R.; Siddiqui, A.; Kelleher, N. L.
10.1101/2024.07.20.604425 — biochemistry — Posted on 2024-07-21
1892 AQuaRef: Machine learning accelerated quantum refinement of protein structures
Zubatyuk, R.; Biczysko, M.; Ranasinghe, K.; Moriarty, N. W.; Gokcan, H.; Kruse, H.; Poon, B. K.; Adams, P. D.; Waller, M. P.; Roitberg, A. E.; Isayev, O.; Afonine, P. V.
10.1101/2024.07.21.604493 — biochemistry — Posted on 2024-07-21
1893 Identification of novel human 15-lipoxygenase-2 (h15-LOX-2) inhibitors using a virtual screening approach
Viviani, L. G.; Iijima, T. S.; Piccirillo, E.; de Rezende, L.; Alegria, T. G. P.; Netto, L. E. S.; do Amaral, A. T.; Miyamoto, S.
10.1101/2024.07.21.604444 — biochemistry — Posted on 2024-07-21
1895 Cross-transmission of resistant gastrointestinal nematodes between wildlife and transhumant sheep
Beaumelle, C.; Toigo, C.; Papet, R.; Benabed, S.; Beurier, M.; Bordes, L.; Brignone, A.; Curt-Grand-Gaudin, N.; Garel, M.; Ginot, J.; Jacquiet, P.; Miquel, C.; Poirel, M.-T.; Serafino, A.; Vannard, E.; Bourgoin, G.; Yannic, G.
10.1101/2023.07.21.550073 — ecology — Posted on 2024-07-21
1896 BCAS2 promotes primitive hematopoiesis by sequestering β-catenin within the nucleus
Ning, G.; Lin, Y.; Ma, H.; Zhang, J.; Yang, L.; Liu, Z.; Li, L.; He, X.; Wang, Q.
10.1101/2024.07.17.603892 — developmental biology — Posted on 2024-07-21
1897 Pharmacologically inducing regenerative cardiac cells by small molecule drugs
Zhou, W.; He, K.; Wang, C.; Wang, P.; Wang, D.; Wang, B.; Geng, H.; Lian, H.; Ma, T.; Nie, Y.; Ding, S.
10.1101/2023.10.24.563872 — cell biology — Posted on 2024-07-21
1898 Mutational landscape and molecular bases of echinocandin resistance
Durand, R.; Torbey, A. G.; Giguere, M.; Pageau, A.; Dube, A. K.; Lagüe, P.; Landry, C. R.
10.1101/2024.07.21.604487 — molecular biology — Posted on 2024-07-21
1899 Discovery and Engineering of Retrons for Precise GenomeEditing
Buffington, J. D.; Kuo, H.-C.; Hu, K.; Chang, Y.-C.; Javanmardi, K.; Voigt, B.; Li, Y.-R.; Little, M. E.; Devanathan, S. K.; Xhemalce, B.; GRAY, R.; Finkelstein, I. J.
10.1101/2024.07.21.604473 — molecular biology — Posted on 2024-07-21
1902 Characterization of a nosocomial outbreak caused by VIM-1 Klebsiella michiganensis using Fourier-Transform Infrared (FT-IR) Spectroscopy
Rodriguez-Temporal, D.; Sanchez-Cueto, M.; Buenestado-Serrano, S.; Blazquez-Sanchez, M.; Cercenado, E.; Gutierrez-Pareja, M.; Molero-Salinas, A.; Lopez-Camacho, E.; Munoz, P.; Garcia de Viedma, D.; Perez-Lago, L.; Rodriguez-Sanchez, B.
10.1101/2024.07.18.604080 — microbiology — Posted on 2024-07-21
1903 Still Not Sterile: Chlorhexidine gluconate treatment does not completely reduce skin microbial bioburden and promotes pathogen overabundance in patients undergoing elective surgeries.
Townsend, E. C.; Xu, K.; De La Cruz, K.; Huang, L.; Sandstrom, S.; Arend, D.; Gromek, O.; Scarborough, J. E.; Huttenlocher, A. C.; Gibson, A.; Kalan, L.
10.1101/2024.07.20.602341 — microbiology — Posted on 2024-07-21
1904 Ablation of B cell-derived IL-10 increases tuberculosis resistance
Hertz, D.; Marwitz, S.; Eggers, L.; von Borstel, L.; Harikumar Parvathy, G.; Behrends, J.; Jonigk, D. D.; Manz, R.; Goldmann, T.; Schneider, B. E.
10.1101/2024.07.17.603865 — immunology — Posted on 2024-07-21
1906 Enhanced purinergic signaling in the paraventricular hypothalamus induces hyperphagic obesity and insulin resistance
Liu, Y.; Zhang, H.; Zhang, Q.; Najam, S. S.; Liang, X.; Sirakawin, C.; Lin, D.; Huang, S.; Bondarenko, A.; Konopka, W.; Zhang, Y.; Zhang, Z.; Wu, S.; Jing, M.; Vinnikov, I. A.
10.1101/2024.07.02.601503 — neuroscience — Posted on 2024-07-21
1908 Linking Gba1 E326K mutation to microglia activation and mild age-dependent dopaminergic Neurodegeneration
Kweon, S. H.; Ryu, H. G.; Park, H.; Lee, S.; Kim, N.; Kwon, S.-H.; Ma, S.; Kim, S.; Ko, H. S.
10.1101/2023.09.14.557673 — neuroscience — Posted on 2024-07-21
1909 Multimodal screen reveals noise regulatory proteins
Garcia-Blay, O.; Hu, X.; Wassermann, C. L.; van Bokhoven, T.; Struijs, F. M. B.; Hansen, M. M. K.
10.1101/2024.07.17.603871 — systems biology — Posted on 2024-07-21
1910 Fine Tuning Genetic Circuits via Host Context and RBS Modulation
Chan, D. T. C.; Winter, L.; Bjerg, J.; Krsmanovic, S.; Baldwin, G. S.; Bernstein, H. C.
10.1101/2024.07.20.604438 — synthetic biology — Posted on 2024-07-21
1911 C-terminally encoded peptides promoting root symbiotic nodulation in legume plants also promote the root arbuscular mycorrhizal symbiotic interaction
Pedinotti, L.; Teyssendier de la Serve, J.; Roudaire, T.; San Clemente, H.; Aguilar, M.; Kohlen, W.; Frugier, F.; Frei dit Frey, N.
10.1101/2024.07.17.603861 — plant biology — Posted on 2024-07-21
1913 DOG1 prevents AFPs activation by AHG1 to control dormancy separately from ABA core signaling
Krueger, T.; Brandt, D.; Sodenkamp, J.; Gasper, M.; Branchat, M.; Ahloumessou, F.; Gehring, E.; Drotleff, J.; Bell, C.; Kramer, K.; Eirich, J.; Soppe, W. J. J.; Finkemeier, I.; Nee, G.
10.1101/2024.07.17.603870 — plant biology — Posted on 2024-07-21
1914 Molecular events accompanying aggregation-induced energy quenching in Fucoxanthin-Chlorophyll Proteins
Alexandre, M. M.; Kruger, T. P.; Pascal, A. A.; Veremeienko, V.; Llansola-Portoles, M.; Gundermann, K.; van Grondelle, R.; Buechel, C.; Robert, B.
10.1101/2024.03.20.585890 — biophysics — Posted on 2024-07-21
1915 PINDER: The protein interaction dataset and evaluation resource
Kovtun, D.; Akdel, M.; Goncearenco, A.; Zhou, G.; Holt, G.; Baugher, D.; Lin, D.; Adeshina, Y.; Castiglione, T.; Wang, X.; Marquet, C.; McPartlon, M.; Geffner, T.; Corso, G.; Stark, H.; Carpenter, Z.; Kucukbenli, E.; Bronstein, M.; Naef, L.
10.1101/2024.07.17.603980 — bioinformatics — Posted on 2024-07-21
1917 Megakaryocyte maturation involves activation of the adaptive unfolded protein response
Faiz, M.; Kalev-Zylinska, M. L.; Dunstan-Harrison, C.; Singleton, D. C.; Hay, M. P.; Ledgerwood, E. C.
10.1101/2023.07.26.550730 — cell biology — Posted on 2024-07-21
1918 Voluntary adolescent alcohol exposure does not robustly increase adulthood consumption of alcohol in multiple mouse and rat models
Sicher, A. R.; Liss, A.; Vozella, V.; Marsland, P.; Seemiller, L. R.; Springer, M.; Starnes, W. D.; Griffith, K. R.; Smith, G. C.; Astefanous, A.; Deak, T.; Roberto, M.; Varodayan, F. P.; Crowley, N. A.
10.1101/2024.04.30.591674 — neuroscience — Posted on 2024-07-21
1919 Tbx1 stabilizes differentiation of the cardiopharyngeal mesoderm and drives morphogenesis in the pharyngeal apparatus
Lanzetta, O.; Bilio, M.; Liebig, J.; Jechow, K.; Ten, F. W.; Ferrentino, R.; Aurigemma, I.; Illingworth, E.; Conrad, C.; Lukassen, S.; Angelini, C.; Baldini, A.
10.1101/2024.07.16.603669 — developmental biology — Posted on 2024-07-21
1920 Striatal endocannabinoid-long-term potentiation mediates one-shot learning
Piette, C.; Hubert, A.; Perez, S.; Berry, H.; Touboul, J. D.; Venance, L.
10.1101/2024.07.10.602953 — neuroscience — Posted on 2024-07-21
1922 High-density sampling reveals volume growth in human tumours
Angaji, A.; Owusu, M.; Velling, C.; Dick, N.; Weghorn, D.; Berg, J.
10.1101/2023.12.10.570995 — cancer biology — Posted on 2024-07-21
1924 Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathways.
Herrmannova, A.; Jelinek, J.; Pospisilova, K.; Kerenyi, F.; Vomastek, T.; Watt, K.; Brabek, J.; Mohammad, M. P.; Wagner, S.; Topisirovic, I.; Valasek, L. S.
10.1101/2023.06.29.547003 — molecular biology — Posted on 2024-07-21
1925 Characterization of a nosocomial outbreak caused by VIM-1 Klebsiella michiganensis using Fourier-Transform Infrared (FT-IR) Spectroscopy
Rodriguez-Temporal, D.; Sanchez-Cueto, M.; Buenestado-Serrano, S.; Blazquez-Sanchez, M.; Cercenado, E.; Gutierrez-Pareja, M.; Molero-Salinas, A.; Lopez-Camacho, E.; Munoz, P.; Garcia de Viedma, D.; Perez-Lago, L.; Rodriguez-Sanchez, B.
10.1101/2024.07.18.604080 — microbiology — Posted on 2024-07-21
1931 Pyramidal neurons proportionately alter the identity and survival of specific cortical interneuron subtypes
Wu, S. J.; Dai, M.; Yang, S.-P.; McCann, C.; Qiu, Y.; Marrero, G. J.; Stogsdill, J. A.; Di Bella, D. J.; Xu, Q.; Farhi, S. L.; Macosko, E. Z.; Chen, F.; Fishell, G.
10.1101/2024.07.20.604399 — neuroscience — Posted on 2024-07-21
1933 A multidimensional investigation of sleep and biopsychosocial profiles with associated neural signatures
Perrault, A. A.; Kebets, V.; Kuek, N. M. Y.; Cross, N. E.; Tesfaye, R.; Pomares, F. B.; Li, J.; Chee, M. W. L.; Dang Vu, T. T.; Yeo, B. T. T.
10.1101/2024.02.15.580583 — neuroscience — Posted on 2024-07-21
1934 Embryo movement is required for limb tendon maturation
Rolfe, R. A.; Talak Basturkmen, E.; Sliney, L.; Hayden, G.; Dunne, N.; Buckley, N.; McCarthy, H.; Szczesny, S.; Murphy, P.
10.1101/2024.07.18.604105 — developmental biology — Posted on 2024-07-21
1936 Spatial constraints and cell surface molecule depletion structure a randomly connected learning circuit
Thornton-Kolbe, E. M.; Ahmed, M.; Gordon, F. R.; Sieriebriennikov, B.; Williams, D. L.; Kurmangaliyev, Y. Z.; Clowney, E. J.
10.1101/2024.07.17.603956 — neuroscience — Posted on 2024-07-21
1937 Hierarchical Bayesian modeling of multi-region brain cell count data
Dimmock, S.; Exley, B. M. S.; Moore, G.; Menage, L.; Delogu, A.; Schultz, S. R.; Warburton, E. C.; Houghton, C. J.; O'Donnell, C.
10.1101/2024.07.20.603979 — neuroscience — Posted on 2024-07-21
1940 Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor
O'Brien, D. P.; Jones, H. B.; Shi, Y.; Guenther, F.; Vendrell, I.; Viner, R.; Brennan, P. E.; Mead, E.; Zarganis-Tzitzikas, T.; Davis, J. B.; Pinto-Fernandez, A.; England, K. S.; Murphy, E. J.; Turnbull, A. P.; Kessler, B. M.
10.1101/2024.07.20.604388 — biochemistry — Posted on 2024-07-20
1942 Lactate-carried Mitochondrial Energy Overflow
Rauseo, D.; Contreras-Baeza, Y.; Faurand, H.; Carcamo, N.; Suarez, R.; von Faber-Castell, A.; Silva, F.; Mora-Gonzalez, V.; Wyss, M. T.; Baeza-Lehnert, F.; Ruminot, I.; Alvarez-Navarro, C.; San Martin, A.; Weber, B.; Sandoval, P. Y.; Barros, L. F.
10.1101/2024.07.19.604361 — biochemistry — Posted on 2024-07-20
1943 Resolving DJ-1 Glyoxalase Catalysis Using Mix-and-Inject Serial Crystallography at a Synchrotron
Zielinski, K. A.; Dolamore, C.; Dalton, K. M.; Smith, N.; Termini, J.; Henning, R.; Srajer, V.; Hekstra, D. R.; Pollack, L.; Wilson, M. A.
10.1101/2024.07.19.604369 — biochemistry — Posted on 2024-07-20
1946 Manganese transporter SLC30A10 and iron transporters SLC40A1 and SLC11A2 impact dietary manganese absorption
Prajapati, M.; Zhang, J. Z.; Chong, G. S.; Chiu, L.; Mercadante, C. J.; Kowalski, H. L.; Antipova, O.; Lai, B.; Ralle, M.; Jackson, B. P.; Punshon, T.; Guo, S.; Aghajan, M.; Bartnikas, T. B.
10.1101/2024.07.17.603814 — genetics — Posted on 2024-07-20
1948 Expansion of the MutS gene family in plants
Sloan, D. B.; Broz, A. K.; Kuster, S. A.; Muthye, V.; Penafiel-Ayala, A.; Marron, J. R.; Lavrov, D. V.; Brieba, L. G.
10.1101/2024.07.17.603841 — evolutionary biology — Posted on 2024-07-20
1949 A facile chemical strategy to synthesize precise AAV-protein conjugates for targeted gene delivery
Pham, Q.; Glicksman, J.; Shahraeini, S. S.; Han, B.; Jewel, D.; Loynd, C.; Singha Roy, S. J.; Chatterjee, A.
10.1101/2024.07.20.604406 — synthetic biology — Posted on 2024-07-20
1951 A scalable genetic tool for the functional analysis of the signal recognition particle.
Long, L. F.; Biskunda, S.; Yang, M.; Wu, G. C.; Simas, C. F.; Bruner, S. D.; Denard, C. A.
10.1101/2024.07.20.602779 — synthetic biology — Posted on 2024-07-20
1953 N6-methyladenosine in DNA promotes genome stability
Conti, B.; Novikov, L.; Tong, D.; Xiang, Q.; Nguyen, C.; Vigil, S.; McLellan, T. J.; De La Cruz, N.; Veettil, R. T.; Pradhan, P.; Sahasrabudhe, P.; Arroyo, J. D.; Shang, L.; Sabari, B. R.; Shields, D. J.; Oppikofer, M.
10.1101/2024.07.20.604187 — molecular biology — Posted on 2024-07-20
1954 Oxygen Microenvironments in E. coli Biofilm Nutrient Transport Channels: Insights from Complementary Sensing Approaches
Bottura, B.; McConnell, G.; Florek, L. C.; Smiley, M. K.; Martin, R.; Eana, A.; Dayton, H. T.; Eckartt, K. N.; Price-Whelan, A.; Hoskisson, P. A.; Dietrich, L. E. P.; Rooney, L. M.
10.1101/2024.07.20.603676 — microbiology — Posted on 2024-07-20
1956 Cryptosporidium Oocyst Wall Proteins are true oocyst wall proteins, with COWP8 functioning to hold the inner and outer layers of the oocyst wall together
Bacchetti, R.; Stevens, S.; Lemgruber, L.; Oliva, M. A. G.; Sands, E. M.; Alexandrou, K.; Tinti, M.; Robinson, L.; Hanna, J. C.; Seizova, S.; Goddard, P.; Vassalli, M.; Pawlowic, M. C.
10.1101/2024.07.20.604394 — microbiology — Posted on 2024-07-20
1960 CONDENSATES OF SYNAPTIC VESICLES AND SYNAPSIN ARE MOLECULAR BEACONS FOR ACTIN SEQUESTERING AND POLYMERIZATION
Chhabra, A.; Hoffmann, C.; Korobeinikov, A.; Rentsch, J.; Kokwaro, L.; Gnidovec, L.; Cristina, R.-V.; Johnson, E.; Wallace, J.; Rankovic, B.; Perego, E.; Koester, S.; Rizzoli, S.; Ewers, H.; Morgan, J.; Milovanovic, D.
10.1101/2024.07.19.604346 — cell biology — Posted on 2024-07-20
1962 Compressive Pangenomics Using Mutation-Annotated Networks
Walia, S.; Motwani, H.; Smith, K.; Corbett-Detig, R.; Turakhia, Y.
10.1101/2024.07.02.601807 — bioinformatics — Posted on 2024-07-20
1963 Doublecortin restricts neuronal branching by regulating tubulin polyglutamylation
Sebastien, M.; Paquette, A. L.; Prowse, E. N. P.; Hendricks, A. G.; Brouhard, G. J.
10.1101/2023.06.02.543327 — cell biology — Posted on 2024-07-20
1964 Salmonella injectisome penetration of macrophages triggers rapid translation of transcription factors and protection against cell death
Wood, G.; Johnson, R.; Powell, J.; Bryant, O.; Lastovka, F.; Brember, M.; Tourlomousis, P.; Carr, J.; Bryant, C.; Chung, B. Y.
10.1101/2023.07.21.550113 — molecular biology — Posted on 2024-07-20
1966 PINDER: The protein interaction dataset and evaluation resource
Kovtun, D.; Akdel, M.; Goncearenco, A.; Zhou, G.; Holt, G.; Baugher, D.; Lin, D.; Adeshina, Y.; Castiglione, T.; Wang, X.; Marquet, C.; McPartlon, M.; Geffner, T.; Corso, G.; Stark, H.; Carpenter, Z.; Kucukbenli, E.; Bronstein, M.; Naef, L.
10.1101/2024.07.17.603980 — bioinformatics — Posted on 2024-07-20
1967 Proteomic analysis identifies dysregulated proteins in albuminuria: a South African pilot study
Khoza, S.; George, J. A.; Naicker, P.; Stoychev, S. H.; Fabian, J.; Govender, I. S.
10.1101/2024.07.16.603438 — biochemistry — Posted on 2024-07-20
1969 Ecological factors alter how spatial overlap predicts viral infection dynamics in wild rodent populations
Mistrick, J.; Veitch, J. S.; Wearing, K. E.; Kitchen, S. M.; Clague, S.; Du, S.; Michalska-Smith, M.; Newman, B. C.; Sironen, T.; Cressler, C. E.; Hall, R. J.; Budischak, S. A.; Forbes, K. M.; Craft, M. E.
10.1101/2024.06.19.599763 — ecology — Posted on 2024-07-20
1970 Plasmodium falciparum disruption of pericyte angiopoietin-1 secretion contributes to barrier breakdown in a 3D brain microvessel model
Long, R. K. M.; Korbmacher, F.; Ronchi, P.; Fleckenstein, H.; Schorb, M.; Mirza, W.; Mallorqui, M.; Aguilar, R.; Moncunill, G.; Schwab, Y.; Bernabeu, M.
10.1101/2024.03.29.587334 — microbiology — Posted on 2024-07-20
1971 Micron-resolution fiber mapping in brain histology independent of sample preparation
Georgiadis, M.; auf der Heiden, F.; Abbasi, H.; Ettema, L.; Nirschl, J.; Moein Taghavi, H.; Wakatsuki, M.; Liu, A.; Ho, W. H. D.; Carlson, M.; Doukas, M.; Koppes, S. A.; Keereweer, S.; Sobel, R. A.; Setsompop, K.; Liao, C.; Amunts, K.; Axer, M.; Zeineh, M. M.; Menzel, M.
10.1101/2024.03.26.586745 — pathology — Posted on 2024-07-20
1974 Deciphering the variation in cuticular hydrocarbon profiles of six European honey bee subspecies
Rodriguez-Leon, D. S.; Uzunov, A.; Costa, C.; Dylan, E. S.; Charistos, L.; Galea, T.; Gabel, M.; Scheiner, R.; Pinto, M. A.; Schmitt, T.
10.1101/2024.07.05.601031 — evolutionary biology — Posted on 2024-07-20
1975 Amoeboid cells undergo durotaxis with soft end polarized NMIIA
Kang, C.; Chen, P.; Yi, X.; Li, D.; Hu, Y.; Yang, Y.; Cai, H.; Li, B.; Wu, C.
10.1101/2023.04.13.536664 — cell biology — Posted on 2024-07-20
1977 An Efficient and Safe Trans-complementation System for MPXV Mimicking Authentic Viral Infection
Liu, J.; Zhu, L.; Mei, L.; Liu, Y.; Qu, Y.; Yuan, Y.; Zhang, F.; Cao, Y.; Zhu, Y.; Tai, W.; Ma, J.; Zheng, M.; Shi, X.; Liu, Y.; Cheng, G.
10.1101/2023.12.29.573498 — microbiology — Posted on 2024-07-20
1979 The 9p21.3 coronary artery disease risk locus drives vascular smooth muscle cells to an osteochondrogenic state
Salido, E.; de Medeiros Vieira, C.; Verdezoto Mosquera, J.; Zade, R.; Miller, C. L.; Lo Sardo, V.
10.1101/2024.05.25.595888 — cell biology — Posted on 2024-07-20
1980 Reduced functional fungal communities in two species of sloths (Bradypus variegatus and Choloepus hoffmanni) suggest a link to slow digestion
Chaverri, P.; Escudero-Leyva, E.; Mora-Rojas, D.; Calvo-Obando, A.; Gonzalez, M.; Escalante-Campos, E.; Mesen-Porras, E.; Wicki-Emmenegger, D.; Rojas-Gatjens, D.; Avey-Arroyo, J.; Campos-Hernandez, M.; Castellon, E.; Moreira-Soto, A.; Drexler, J. F.; Chavarria, M.
10.1101/2024.07.19.604311 — microbiology — Posted on 2024-07-20
1982 Dnmt1 determines bone length by regulating energy metabolism of growth plate chondrocytes
Yanagihara, Y.; Takahashi, M.; Yoshihiro, I.; Kinoshita, T.; Takao, M.; Bamba, T.; Imai, Y.
10.1101/2024.07.17.604010 — developmental biology — Posted on 2024-07-20
1983 Frequency coding of multisensory integration in the local field potentials of the medial pulvinar
Vittek, A.-L.; Juan, C.; Gaillard, C.; Mercier, M.; Girard, P.; Ben Hamed, S.; Cappe, C.
10.1101/2024.07.18.604099 — neuroscience — Posted on 2024-07-20
1985 Central Nervous System Control of breathing in Natural Conversational Turn-Taking
Di Pasquasio, C.; De Pellegrin, L.; Pineaud, A.; Marty, A.; Chaminade, T.
10.1101/2024.07.17.603521 — neuroscience — Posted on 2024-07-20
1986 Encoding of cerebellar dentate neuronal activity during visual attention in rhesus macaques
Flierman, N. A.; Koay, S. A.; van Hoogstraten, W. S.; Ruigrok, T. J. H.; Roelfsema, P.; Badura, A.; De Zeeuw, C. I.
10.1101/2024.07.18.604119 — neuroscience — Posted on 2024-07-20
1987 Systematic identification of Y-chromosome gene functions in mouse spermatogenesis
Subrini, J.; Varsally, W.; Balaguer Balsells, I.; Bensberg, M.; Sioutas, G.; Ojarikre, O.; Maciulyte, V.; Gylemo, B.; Crawley, K.; Courtis, K.; de Rooij, D. G.; Turner, J. M.
10.1101/2024.07.18.604063 — genetics — Posted on 2024-07-19
1990 Altered calcium responses and antioxidant properties in Friedreich's ataxia-like cerebellar astrocytes
Marullo, C.; Croci, L.; Giupponi, I.; Rivoletti, C.; Zuffetti, S.; Bettegazzi, B.; Casoni, F.; Cremona, O.; Consalez, G.; Codazzi, F.
10.1101/2024.07.19.604129 — cell biology — Posted on 2024-07-20
1991 Sex-dependent gastrointestinal colonization resistance to MRSA is microbiome and Th17 dependent
Lejeune, A.; Zhou, C.; Ercelen, D.; Putzel, G.; Yao, X.; Guy, A. R.; Pawline, M.; Podkowik, M.; Pironti, A.; Torres, V. J.; Shopsin, B.; Cadwell, K.
10.1101/2024.07.17.603994 — immunology — Posted on 2024-07-19
1993 The temporal refinement of Dach1 is a key step in the functional maturation of primary somatosensory neurons
Szemes, T.; Sabate San Jose, A.; Azouz, A.; Sitte, M.; Salinas, G.; Achouri, Y.; Kricha, S.; Ris, L.; Red-Horse, K.; Bellefroid, E. J.; Desiderio, S.
10.1101/2024.07.18.604081 — neuroscience — Posted on 2024-07-20
1996 Evolution of intrinsic transcriptional terminators in their genomic context
Toledo-Aparicio, D.; Denisov, S.; Bernard, C.; Redondo, R. A.; Carter, C. C.; Khomarbaghi, Z.; Pittrich, D. A.; Nagy-Staron, A.; Guet, C. C.; Lagator, M.
10.1101/2024.07.17.603904 — evolutionary biology — Posted on 2024-07-19
1997 The evolutionary ancient MEIS transcription factors actuate lineage-specific transcription to establish cardiac fate
Bobola, N.; Darieva, Z.; Zarrineh, P.; Phillips, N.; Mallen, J.; Garcia Mora, A.; Donaldson, I.; Bridoux, L.; Douglas, M.; Dias Henriques, S.; Schulte, D.; Birket, M.
10.1101/2024.07.18.604075 — developmental biology — Posted on 2024-07-19
1999 A Necrotizing Toxin Promotes Pseudomonas syringae Infection Across Evolutionarily Divergent Plant Lineages
Grenz, K.; Chia, K.-S.; Turley, E. K.; Tyszka, A. S.; Atkinson, R. E.; Reeves, J.; Vickers, M.; Rejzek, M.; Walker, J. F.; Carella, P.
10.1101/2024.07.17.603760 — plant biology — Posted on 2024-07-19
2001 The dynamic and diverse nature of parenchyma cells in the Arabidopsis root during secondary growth
Lyu, M.; Iida, H.; Eekhout, T.; Makela, M.; Muranen, S.; Ye, L.; Vaten, A.; Wybouw, B.; Wang, X.; De Rybel, B.; Mahonen, A. P.
10.1101/2024.07.18.604073 — plant biology — Posted on 2024-07-19
2002 Viral delivery of an RNA-guided genome editor for transgene-free plant germline editing
Weiss, T.; Kamalu, M.; Shi, H.; Li, Z.; Amerasekera, J.; Adler, B. A.; Song, M.; Vohra, K.; Wirnowski, G.; Chitkara, S.; Ambrose, C.; Steinmetz, N.; Sridharan, A.; Sahagun, D.; Banfield, J.; Doudna, J.; Jacobsen, S. E.
10.1101/2024.07.17.603964 — plant biology — Posted on 2024-07-19
2003 Epigenomic manipulation reveals the relationship between locus specific chromatin dynamics and gene expression
Venu, V.; Small, E. M.; Roth, C.; Adikari, S. H.; Vlot, A. H. C.; Sullivan, K. A.; Abeyratne, C. R.; Jacobson, D.; Starkenburg, S. R.; Sanbonmatsu, K. Y.; Steadman, C. R.
10.1101/2024.07.17.603961 — cancer biology — Posted on 2024-07-19
2005 RWRtoolkit: multi-omic network analysis using random walks on multiplex networks in any species
Kainer, D.; Lane, M.; Sullivan, K. A.; Miller, J. I.; Cashman, M.; Morgan, M.; Cliff, A.; Romero, J.; Walker, A.; Blair, D. D.; Chhetri, H.; Wang, Y.; Pavicic, M.; Furches, A.; Noshay, J.; Drake, M.; Landry, N.; Ireland, A.; Missaoui, A.; Kang, Y.; Sedbrook, J.; Dehal, P.; Canon, S.; Jacobson, D. A.
10.1101/2024.07.17.603975 — bioinformatics — Posted on 2024-07-19
2009 PINDER: The protein interaction dataset and evaluation resource
Kovtun, D.; Akdel, M.; Goncearenco, A.; Zhou, G.; Holt, G.; Baugher, D.; Lin, D.; Adeshina, Y.; Castiglione, T.; Wang, X.; Marquet, C.; McPartlon, M.; Geffner, T.; Corso, G.; Stark, H.; Carpenter, Z.; Kucukbenli, E.; Bronstein, M.; Naef, L.
10.1101/2024.07.17.603980 — bioinformatics — Posted on 2024-07-19
2011 Long-read sequencing transcriptome quantification with lr-kallisto
Loving, R. K.; Sullivan, D. K.; Reese, F.; Rebboah, E.; Sakr, J.; Rezaie, N.; Liang, H. Y.; Filimban, G.; Kawauchi, S.; Oakes, C.; Trout, D.; Williams, B. A.; MacGregor, G.; Wold, B.; Mortazavi, A.; Pachter, L.
10.1101/2024.07.19.604364 — bioinformatics — Posted on 2024-07-19
2013 Deep learning guided design of dynamic proteins
Guo, A. B.; Akpinaroglu, D.; Kelly, M.; Kortemme, T.
10.1101/2024.07.17.603962 — bioengineering — Posted on 2024-07-19
2014 Microbial photoproduction of heptane
BACA-PORCEL, A.; LEGERET, B.; AUROY-TARRAGO, P.; VEILLET, F.; GIACALONE, C.; Cuine, S.; Palakiyem SAMIRE, P.; MOULIN, S.; LI-BEISSON, Y.; BEISSON, F.; Sorigue, D.
10.1101/2024.07.17.603920 — bioengineering — Posted on 2024-07-19
2016 Structural basis for allosteric regulation of the proteasome core particle
Turner, M.; Uday, A. B.; Velyvis, A.; Rennella, E.; Zeytuni, N.; Vahidi, S.
10.1101/2024.07.19.604198 — biochemistry — Posted on 2024-07-19
2020 Biased agonism of carvedilol in the beta1-adrenergic receptor is governed by conformational exclusion
Abiko, L. A.; Petrovic, I.; Tatli, M.; Desai, S.; Stahlberg, H.; Spang, A.; Grzesiek, S.
10.1101/2024.07.19.604263 — biochemistry — Posted on 2024-07-19
2025 Ancient Borrelia genomes document the evolutionary history of louse-borne relapsing fever
Swali, P.; Booth, T.; Tan, C. C. S.; McCabe, J.; Anastasiadou, K.; Barrington, C.; Borrini, M.; Bricking, A.; Buckberry, J.; Buster, L.; Carlin, R.; Gilardet, A.; Glocke, I.; Irish, J.; Kelly, M.; King, M.; Petchey, F.; Peto, J.; Silva, M.; Speidel, L.; Tait, F.; Teoaca, A.; Valoriani, S.; Williams, M.; Madgwick, R.; Mullan, G.; Wilson, L.; Cootes, K.; Armit, I.; Gutierrez, M. G.; van Dorp, L.; Skoglund, P.
10.1101/2024.07.18.603748 — evolutionary biology — Posted on 2024-07-19
2028 Reproductive resource allocation correlates with successful global invasion of a mosquito species
Khorramnejad, A.; Alfaro, C. C.; Quaranta, S.; Lozada-Chavez, A. N.; Gasmi, L.; Perdomo, H. D.; Chiarelli, L. R.; Bonizzoni, M.
10.1101/2024.07.18.604133 — evolutionary biology — Posted on 2024-07-19
2035 Long range regulation of transcription scales with genomic distance in a gene specific manner
Jensen, C. L.; Chen, L.-F.; Swigut, T.; Crocker, O. J.; Yao, D.; Bassik, M. C.; Ferrell, J.; Boettiger, A.; Wysocka, J.
10.1101/2024.07.19.604327 — molecular biology — Posted on 2024-07-19
2036 Mesoscale chromatin confinement facilitates target search of pioneer transcription factors in live cells
Wang, Z.; Wang, B.; Niu, D.; Yin, C.; Bi, Y.; Cattoglio, C.; Loh, K. M.; Lavis, L. D.; Ge, H.; Deng, W.
10.1101/2024.07.18.604200 — molecular biology — Posted on 2024-07-19
2037 Lipotoxicity Induces Beta Cell Small Extracellular Vesicle-mediated Beta Cell Dysfunction
Roy, A.; Hoff, A.; Her, T. K.; Ariyaratne, G.; Sankaran Rajagopalan, K.; Brown, M. R.; Soto-Gonzalez, A.; Matveyenko, A. V.; Javeed, N.
10.1101/2024.07.19.604353 — molecular biology — Posted on 2024-07-19
2041 Immune disease dialogue of chemokine-based cell communications as revealed by single-cell RNA sequencing meta-analysis
Rahman, M. F.; Kurlovs, A. H.; Vodnala, M.; Meibalan, E.; Means, T. K.; Nouri, N.; de Rinaldis, E.; Savova, V.
10.1101/2024.07.17.603936 — immunology — Posted on 2024-07-19
2042 Discrimination of Jamaican fruit bat lymphocytes by flow cytometry
Burke, B. E.; Rocha, S. M.; Campbell, C. L.; Creissen, E.; Tjalkens, R.; Ma, W.; Henao-Tamayo, M. I.; Schountz, T.
10.1101/2024.07.18.604131 — immunology — Posted on 2024-07-19
2043 The noncoding circular RNA circHomer1 regulates developmental experience-dependent plasticity in mouse visual cortex
Jenks, K. R.; Cai, Y.; Nayan, M. E.; Tsimring, K.; Li, K.; Zepeda, J. C.; Heller, G. R.; Delepine, C.; Shih, J.; Yuan, S.; Zhu, Y.; Wang, Y.; Duan, Y.; Fu, A. K. Y.; Ku, T.; Yun, D. H.; Chung, K.; Zhang, C.; Boyden, E. S.; Mellios, N.; Sur, M.; Ip, J. P. K.
10.1101/2024.07.19.603416 — neuroscience — Posted on 2024-07-19
2044 Surfing beta burst waveforms to improve motor imagery-based BCI
Papadopoulos, S.; Darmet, L.; Szul, M. J.; Congedo, M.; Bonaiuto, J. J.; Mattout, J.
10.1101/2024.07.18.604064 — neuroscience — Posted on 2024-07-19
2046 Preventing escape and malfunction of recoded cells due to tRNA base changes
Chiappino-Pepe, A.; Radford, F.; Budnik, B.; Tas, H.; Augustin, T. L.; Burgess, H. M.; Moret, M.; Dharani, A. M.; Zheng, Q.; Fan, W.; Afrikawala, M. M.; Thapa, S.; Kuru, E.; Narasimhan, K.; Marchand, J. A.; Perrotta, R. M.; Stokes, J. M.; Lunshof, J. E.; Aach, J. D.; Tam, J. M.; Church, G. M.
10.1101/2024.07.18.604179 — synthetic biology — Posted on 2024-07-19
2047 A modular cell-free protein biosensor platform using split T7 RNA polymerase
McSweeney, M. A.; Patterson, A. T.; Loeffler, K.; Cuellar Lelo de Larrea, R.; McNerney, M. P.; Kane, R. S.; Styczynski, M. P.
10.1101/2024.07.19.604303 — synthetic biology — Posted on 2024-07-19
2050 Evaluation of intercellular and extracellular synthesis of biogenic amines by the aquatic moss Vesicularia dubyana
Belyshenko, A. Y.; Morgunova, M. M.; Malygina, E. V.; Dmitrieva, M. E.; Imidoeva, N. A.; Shelkovnikova, V. N.; Telnova, T. Y.; Vlasova, A. A.; Vavilina, T. N.; Tretyakova, A. V.; Axenov-Gribanov, D. V.
10.1101/2024.07.19.604072 — plant biology — Posted on 2024-07-19
2053 Structural characterization of two full length γδTCR/CD3 complexes
Hoque, M.; Grigg, J. B.; Ramlall, T.; Jones, J.; McGoldrick, L. L.; Olson, W. C.; Lin, J. C.; Smith, E.; Franklin, M. C.; Zhang, T.; Saotome, K.
10.1101/2024.07.19.604350 — biochemistry — Posted on 2024-07-19
2055 Accurate Predictions of Phase Separating Proteins at Single Amino Acid Resolution
Monti, M.; Fiorentino, J.; Vrachnos, D.; Bini, G.; Cotrufo, T.; Sanchez, N.; Armaos, A.; Tartaglia, G. G.
10.1101/2024.07.19.602785 — biochemistry — Posted on 2024-07-19
2058 Enhancing gRNA Transcript levels by Reducing the Scaffold Poly-T Tract for Optimal SpCas9- and SaCas9-mediated Gene Editing
Chey, Y. C. J.; Gierus, L.; Lushington, C.; Arudkumar, J. C.; Geiger, A.; Staker, L. G.; Robertson, L. J.; Pfitzner, C.; Kennedy, J. G.; Lee, R. H. B.; Godahewa, G. I.; Thomas, P. Q.; Adikusuma, F.
10.1101/2024.07.19.604224 — molecular biology — Posted on 2024-07-19
2059 Engineering the novel extremophile alga Chlamydomonas pacifica for high lipid and high starch production as a path to developing commercially relevant strains
Gupta, A.; Dutra Molino, J. V.; Wnuk-Fink, K. M.; Bruckbauer, A.; Tessman, M.; Kang, K.; Diaz, C. J.; Saucedo, B.; Malik, A.; Mayfield, S. P.
10.1101/2024.07.18.604193 — molecular biology — Posted on 2024-07-19
2060 High-throughput method rapidly characterizes hundreds of novel antibiotic resistance mutations
Jago, M. J.; Soley, J. K.; Denisov, S.; Walsh, C. J.; Gifford, D. R.; Howden, B. P.; Lagator, M.
10.1101/2024.07.19.604246 — microbiology — Posted on 2024-07-19
2063 Multiple dermal cell types support productive infection and dynamic translocation of infectious Ebola virus to the apical surface of human skin
Messingham, K.; Richards, P. T.; Fleck, A.; Patel, R. A.; Djurkovic, M.; Elliff, J.; Connell, S.; Gonzalez, J. P. M.; Gourronc, F. A.; Dillard, J. A.; Davey, R. A.; Klingelhutz, A. J.; Shtanko, O.; Maury, W.
10.1101/2024.07.19.604135 — microbiology — Posted on 2024-07-19
2064 Blood-based detection of MMP11 as a marker of prostate cancer progression regulated by the ALDH1A1-TGF-β1 signaling mechanism
Gorodetska, I.; Lukiyanchuk, V.; Gawin, M.; Sliusar, M.; Linge, A.; Lohaus, F.; Hölscher, T.; Erdmann, K.; Fuessel, S.; Borkowetz, A.; Reardon, M.; Choudhury, A.; Antonelli, Y.; Leal-Egana, A.; Köseer, A. S.; Kahya, U.; Püschel, J.; Klusa, D.; Peitzsch, C.; Kronstein-Wiedemann, R.; Tonn, T.; Thomas, C.; Widłak, P.; Pietrowska, M.; Krause, M.; Dubrovska, A.
10.1101/2024.07.16.603771 — cancer biology — Posted on 2024-07-19
2068 The role of YAP/TAZ signaling in dendritic cell-mediated pathogenesis of insulin resistance and non-alcoholic fatty liver disease
Schcolnik-Cabrera, A.; Lee, M.; Dzierlaga, K.; Basso, P.; Strachan, E.; Zhu, M.; Akbari, M.; Clemente-Casares, X.; Tsai, S.
10.1101/2024.07.16.603813 — immunology — Posted on 2024-07-19
2070 Inhibition of CD226 Co-Stimulation Suppresses Diabetes Development in the NOD Mouse by Augmenting Tregs and Diminishing Effector T Cell Function
Brown, M.; Thirawatananond, P.; Peters, L.; Kern, E.; Vijay, S.; Sachs, L.; Posgai, A. L.; Brusko, M.; Shapiro, M.; Mathews, C. E.; Bacher, R. E.; Brusko, T.
10.1101/2024.07.16.603756 — immunology — Posted on 2024-07-19
2074 SSRI antidepressant citalopram reverses the Warburg effect to inhibit hepatocellular carcinoma by directly targeting GLUT1
Dong, F.; He, K.; Zhang, S.; Song, K.; Jiang, L.; Hu, L.; Li, Q.; Zhang, X.-L.; Zhang, N.; Li, B.-T.; Zhu, L.-L.; Li, J.; Feng, M.; Gao, Y.; Chen, J.; Hu, X.; Wang, J.; Jiang, C.; Zhu, H.; Da, L.; Ji, J.; Bao, Z.; Jiang, S.-H.
10.1101/2024.07.17.603851 — cancer biology — Posted on 2024-07-19
2078 Representing Transcription Factor Dimer Binding Sites Using Forked-Position Weight Matrices and Forked-Sequence Logos
Matthew, D.; Roberto, T.-M.; Aida, G.-K.; Quy, X. X. L.; Walter, S.; Hamid, U.; Morgane, T.-C.; Sudhakar, J.; Denis, T.; Touati, B.
10.1101/2024.07.16.603695 — bioinformatics — Posted on 2024-07-19
2079 Wearable facemask-attached disposable printed sensor arrays for point-of-need monitoring of ammonia in breath
Barandun, G.; Sanli, A.; Yap, C. L.; Collins, A. S. P.; Grell, M.; Kasimatis, M.; Levy, J.; Guder, F.
10.1101/2024.07.16.603629 — bioengineering — Posted on 2024-07-19
2081 Cross-Tissue Comparison of Epigenetic Aging Clocks in Humans
Apsley, A. T.; Ye, Q.; Caspi, A.; Chiaro, C.; Etzel, L.; Hastings, W. J.; Heim, C. C.; Kozlosky, J.; Noll, J.; Schreier, H. M. C.; Shenk, C. E.; Sugden, K.; Shalev, I.
10.1101/2024.07.16.603774 — genomics — Posted on 2024-07-19
2082 The first complete mitochondrial genome of tjakura (Great Desert Skink, Liopholis kintorei)
Thuo, D.; Macgregor, N. A.; Keogh, J. S.; Goumas, M.; Swan, S.; Guest, T.; Doerr, E. D.; Wallace, J.; Paltridge, R.; Kenny, J.; Merson, S. D.; Leo, J.
10.1101/2024.07.17.603866 — genomics — Posted on 2024-07-19
2083 Pf-HaploAtlas: an interactive web app for spatiotemporal analysis of P. falciparum genes
Lee, C.; Ünlü, E. S.; White, N. F.; Almagro-Garcia, J.; Ariani, C.; Pearson, R. D.
10.1101/2024.07.16.603783 — genomics — Posted on 2024-07-19
2085 Alternative splicing controls pan-neuronal homeobox gene expression
Leyva-Diaz, E.; Cesar, M.; Pe, K.; Jorda-Llorens, J. I.; Valdivia, J.; Hobert, O.
10.1101/2024.07.16.603806 — developmental biology — Posted on 2024-07-19
2086 Mll4 regulates postnatal palate growth and midpalatal suture development
Lee, J.-M.; Jung, H.; de Paula Machado Pasqua, B.; Park, Y.; Jeon, S.; Lee, S.-K.; Lee, J. W.; Kwon, H.-J. E.
10.1101/2024.07.16.603832 — developmental biology — Posted on 2024-07-19
2087 Engineered NKG2C+ NK-like T cells exhibit superior antitumor efficacy while mitigating cytokine release syndrome
Lupo, K. B.; Panjwani, M. K.; Shahid, S.; Sottile, R.; Lawry, C.; Kolk, G.; Kontopolous, T.; Daniyan, A. F.; Chandran, S. S.; Klebanoff, C. A.; Hsu, K. C.
10.1101/2024.07.16.603785 — immunology — Posted on 2024-07-19
2088 Temporal asymmetry of neural representations predicts memory decisions
Ye, Z.; Zhao, Y.; Allen, E. J.; Naselaris, T.; Kay, K.; Hutchinson, J. B.; Kuhl, B. A.
10.1101/2024.07.16.603778 — neuroscience — Posted on 2024-07-19
2090 Spatiotemporal transcriptomic profiling and modeling of mouse brain at single-cell resolution reveals cell proximity effects of aging and rejuvenation
Sun, E. D.; Zhou, O. Y.; Hauptschein, M.; Rappoport, N.; Xu, L.; Navarro Negredo, P.; Liu, L.; Rando, T. A.; Zou, J.; Brunet, A.
10.1101/2024.07.16.603809 — neuroscience — Posted on 2024-07-19
2091 Perturbed pediatric serum metabolome in mild and severe dengue disease
Soma, P. S.; Gullberg, R. C.; Graham, B.; Islam, M. N.; Balmaseda, A.; Blair, C. D.; Beaty, B.; Belisle, J. T.; Harris, E.; Perera, R.
10.1101/2024.07.16.603788 — systems biology — Posted on 2024-07-19
2093 A viscoelastic-plastic deformation model of hemisphere-like tip growth in Arabidopsis zygotes
Kang, Z.; Nonoyama, T.; Ishimoto, Y.; Matsumoto, H.; Nakagawa, S.; Ueda, M.; Tsugawa, S.
10.1101/2024.07.17.603843 — plant biology — Posted on 2024-07-19
2094 Deletion of the endothelial glycocalyx component endomucin leads to impaired glomerular structure and function
Hu, Z.; Cano, I.; Lei, F.; Liu, J.; Bossardi Ramos, R.; Gordon, H.; Paschalis, E. I.; Saint-Geniez, M.; Ng, Y. S. E.; D'Amore, P. A.
10.1101/2024.07.16.603749 — pathology — Posted on 2024-07-19
2095 FLASH radiotherapy using high-energy X-rays: validation of the FLASH effect triggered by a compact single high-energy X-ray source device
Lin, B.; Du, H.; Yang, Y.; Hao, X.; Gao, F.; Liang, Y.; Tang, W.; Xu, H.; Tang, M.; Liao, Y.; Wang, D.; Lin, B.; Zhu, Y.; Zhang, Y.; Li, J.; zhou, z.; Wang, J.; Wu, D.; Du, X.
10.1101/2024.07.16.603758 — cancer biology — Posted on 2024-07-19
2098 Microphysiological system modeling pericyte-induced temozolomide resistance in glioblastoma
Maity, S.; Jewell, C.; Yilgor, C.; Kawakita, S.; Sharma, S.; Gomez, A.; Mecwan, M.; Falcone, N.; Ermis, M.; Monirizad, M.; Hosseinzadeh Kouchehbaghi, N.; Zehtabi, F.; Khorsandi, D.; Dokmeci, M. R.; Moniz-Garcia, D.; Quinones-Hinojosa, A.; Khademhosseini, A.; Jucaud, V.
10.1101/2024.07.16.603611 — bioengineering — Posted on 2024-07-19
2101 Adult caudal fin shape is imprinted in the embryonic fin fold
Surette, E.; Donahue, J.; Robinson, S.; McKenna, D.; Soto Martinez, C.; Fitzgerald, B.; Karlstrom, R.; Cumplido, N.; McMenamin, S. K.
10.1101/2024.07.16.603744 — developmental biology — Posted on 2024-07-19
2103 RAB12-LRRK2 Complex Suppresses Primary Ciliogenesis and Regulates Centrosome Homeostasis in Astrocytes
Li, X.; Zhu, H.; Huang, B. T.; Li, X.; Kim, H.; Tan, H.; Zhang, Y.; Choi, I.; Peng, J.; Xu, P.; Sun, J.; Yue, Z.
10.1101/2024.07.17.603999 — neuroscience — Posted on 2024-07-19
2105 Beyond Auditory Relay: Dissecting the Inferior Colliculus's Role in Sensory Prediction, Cognitive Decision-Making, and Reward Prediction
Du, X.; Xu, H.; Song, P.; Zhai, Y.; Ye, H.; Bao, X.; Huang, Q.; Tanigawa, H.; Tu, Z.; Chen, P.; Zhao, X.; P. Rauschecker, J.; Yu, X.
10.1101/2024.07.16.603747 — neuroscience — Posted on 2024-07-19
2106 Social odors drive hippocampal CA2 place cell responses to social stimuli
Robson, E.; Donahue, M. M.; Mably, A. J.; Demetrovich, P. G.; Hewitt, L. T.; Colgin, L. L.
10.1101/2024.07.16.603738 — neuroscience — Posted on 2024-07-19
2107 Mechanism of auxin-dependent gene regulation through composite auxin response elements
Novikova, D. D.; Omelyanchuk, N.; Korosteleva, A.; Albrecht, C.; Lavrekha, V. V.; Weijers, D.; Mironova, V.
10.1101/2024.07.16.603724 — plant biology — Posted on 2024-07-19
2109 Molecular consequences of acute versus chronic CDK12 loss in prostate carcinoma nominates distinct therapeutic strategies
Frank, S.; Persse, T.; Coleman, I. M.; Bankhead, A.; Li, D.; DeSarkar, N.; Wilson, D.; Rudoy, D.; Vashisth, M.; Galipeau, P.; Yang, M.; Hanratty, B.; Dumpit, R.; Morrissey, c.; Corey, E.; Montgomery, R.; Haffner, M.; Pritchard, C.; Vasioukhin, V.; Ha, G.; Nelson, P. S.
10.1101/2024.07.16.603734 — cancer biology — Posted on 2024-07-19
2111 ADToolbox: Incorporating Metagenomics Data for Improved Prediction of Anaerobic Digestion Dynamics
Ghadermazi, P.; Rico, J. L.; Rimelman, E.; Stenmark, S.; Reardon, K. F.; De Long, S. K.; Chan, S. H. J.
10.1101/2024.07.16.603753 — bioengineering — Posted on 2024-07-19
2114 Neural dynamics underlying minute-timescale persistent behavior in the human brain
Courellis, H.; Valiante, T. A.; Mamelak, A. N.; Adolphs, R.; Rutishauser, U.
10.1101/2024.07.16.603717 — neuroscience — Posted on 2024-07-19
2115 Thyroid hormones maintain parvalbumin neuron functions in mouse neocortex
Ren, J.; Markossian, S.; Guyot, R.; Aubert, D.; Li, D.; Cauli, B.; Riet, F.; Wong, J.; Flamant, F.; Richard, S.
10.1101/2024.07.16.603713 — neuroscience — Posted on 2024-07-19
2118 Gibberellic acid and light effects on seed germination in the seagrass Zostera marina
Pieraccini, R.; Whatley, L.; Koedam, N.; Dierick, J.; Vanreusel, A.; Dolch, T.; Van der Stocken, T.
10.1101/2024.07.16.603723 — plant biology — Posted on 2024-07-19
2120 The molecular impact of cigarette smoking resembles aging across tissues
Ramirez, J. M.; Ribeiro, R.; Soldatkina, O.; Moraes, A.; Garcia-Perez, R.; Ferreira, P. G.; Mele, M.
10.1101/2024.03.14.585016 — bioinformatics — Posted on 2024-07-19
2121 Modeling causal signal propagation in multi-omic factor space with COSMOS
Dugourd, A.; Lafrenz, P.; Mananes, D.; Paton, V.; Fallegger, R.; Kroger, A.-C.; Turei, D.; Shtylla, B.; Saez-Rodriguez, J.
10.1101/2024.07.15.603538 — bioinformatics — Posted on 2024-07-19
2122 Sensing endogenous RNA in living human cells using a CRISPR-activated protease
Blumenstock, K.; Hoch, A.; Hinterlang, L. D.; Caroline, F.; Schneberger, N.; Hagelueken, G.; Schmid-Burgk, J. L.
10.1101/2024.07.17.603943 — bioengineering — Posted on 2024-07-19
2123 Hierarchical structural organization in bioinspired peptide coacervate microdroplets
Lim, J.; Gudlur, S.; Buchanan, C.; Perrin, Q.; Boyd, H.; Moulin, M.; Iwase, H.; Porcar, L.; Cardenas, M.; Miserez, A.; Pervushin, K.
10.1101/2024.07.06.602323 — biochemistry — Posted on 2024-07-19
2124 Molecular basis for plasma membrane recruitment of PI4KA by EFR3
Suresh, S.; Shaw, A. L.; Pemberton, J. G.; Scott, M. K.; Harris, N. J.; Parson, M. A.; Jenkins, M. L.; Rohilla, P.; Prats, A. A.; Balla, T.; Yip, C. K.; Burke, J. E.
10.1101/2024.04.30.587787 — biochemistry — Posted on 2024-07-19
2125 PLINDER: The protein-ligand interactions dataset and evaluation resource
Durairaj, J.; Adeshina, Y.; Cao, Z.; Zhang, X.; Oleinikovas, V.; Duignan, T.; McClure, Z.; Robin, X.; Studer, G.; Kovtun, D.; Rossi, E.; Zhou, G.; Veccham, S.; Isert, C.; Peng, Y.; Sundareson, P.; Akdel, M.; Corso, G.; Stärk, H.; Tauriello, G.; Carpenter, Z.; Bronstein, M.; Kucukbenli, E.; Schwede, T.; Naef, L.
10.1101/2024.07.17.603955 — biochemistry — Posted on 2024-07-19
2126 Structure of Calcineurin bound to PI4KA reveals dual interface in both PI4KA and FAM126A
Shaw, A. L.; Suresh, S.; Parson, M. A.; Harris, N. J.; Jenkins, M. L.; Yip, C. K.; Burke, J. E.
10.1101/2024.04.09.588654 — biochemistry — Posted on 2024-07-19
2134 Interaction of GAT1 with sodium ions: from efficient recruitment to stabilisation of substrate and conformation
Lazzarin, E.; Gradisch, R.; Skopec, S. M.; Alves da Silva, L.; Sebastianelli-Schoditsch, C.; Szollosi, D.; Maier, J.; Sucic, S.; Roblek, M.; Kanner, B.; Sitte, H. H.; Stockner, T.
10.1101/2023.10.10.561652 — molecular biology — Posted on 2024-07-19
2136 A conserved cell-pole determinant organizes proper polar flagellum formation
Arroyo-Perez, E. E.; Hook, J. C.; Alvarado, A.; Wimmi, S.; Glatter, T.; Thormann, K. M.; Ringgaard, S.
10.1101/2023.09.20.558563 — microbiology — Posted on 2024-07-19
2137 Expansion-assisted selective plane illumination microscopy for nanoscale imaging of centimeter-scale tissues
Glaser, A.; Chandrashekar, J.; Vasquez, J.; Arshadi, C.; Ouellette, N.; Jiang, X.; Baka, J.; Kovacs, G.; Woodard, M.; Seshamani, S.; Cao, K.; Clack, N.; Recknagel, A.; Grim, A.; Balaram, P.; Turschak, E.; Hooper, M.; Liddell, A.; Rohde, J.; Hellevik, A.; Takasaki, K.; Erion Barner, L.; Logsdon, M.; Chronopoulos, C.; de Vries, S.; Ting, J.; Perlmutter, S.; Kalmbach, B.; Dembrow, N.; Tasic, B.; Reid, R. C.; Feng, D.; Svoboda, K.
10.1101/2023.06.08.544277 — neuroscience — Posted on 2024-07-19
2140 Bacterial stress granule protects mRNA through ribonucleases exclusion
Pei, L.; Xian, Y.; Yan, X.; Schaefer, C.; Syeda, A. H.; Howard, J.; Liao, H.; Bai, F.; Leake, M. C.; Pu, Y.
10.1101/2024.04.27.591437 — biophysics — Posted on 2024-07-19
2142 Human reproduction comes at the expense of faster aging and a shorter life
Hukkanen, M.; Kankaanpaa, A.; Heikkinen, A.; Kaprio, J.; Cristofari, R.; Ollikainen, M.
10.1101/2024.07.18.603826 — evolutionary biology — Posted on 2024-07-19
2144 Cryo-EM structure of the CBC-ALYREF complex
Clarke, B. P.; Angelos, A. E.; Mei, M.; Hill, P. S.; Xie, Y.; Ren, Y.
10.1101/2023.10.01.559959 — molecular biology — Posted on 2024-07-19
2145 Deletion of adipocyte Sine Oculis Homeobox Homolog 1 prevents lipolysis and attenuates skin fibrosis.
Wareing, N.; Mills, T. W.; Collum, S.; Wu, M.; Revercomb, L.; Girard, R.; Lyons, M.; Skaug, B.; Bi, W.; Ali, M. A.; Koochak, H.; Flores, A. R.; Yang, Y.; Zheng, W. J.; Swindell, W.; Assassi, S.; Karmouty-Quintana, H.
10.1101/2024.05.22.595271 — molecular biology — Posted on 2024-07-19
2148 Brain Structural Correlates of an Impending Initial Major Depressive Episode
Kraus, A.; Dohm, K.; Borgers, T.; Goltermann, J.; Grotegerd, D.; Winter, A.; Thiel, K.; Flinkenfluegel, K.; Schuermeyer, N.; Hahn, T.; Langer, S.; Kircher, T.; Nenadic, I.; Straube, B.; Jamalabadi, H.; Alexander, N.; Jansen, A.; Stein, F.; Brosch, K.; Usemann, P.; Teutenberg, L.; Thomas-Odenthal, F.; Meinert, S.; Dannlowski, U.
10.1101/2024.07.19.604266 — neuroscience — Posted on 2024-07-19
2150 Spatiotemporal resonance in mouse primary visual cortex
Gulbinaite, R.; Nazari, M.; Rule, M. E.; Bermudez Contreras, E. J.; Cohen, M. X.; Mohajerani, M. H.; Heimel, J. A.
10.1101/2023.07.31.551212 — neuroscience — Posted on 2024-07-19
2151 Engineered endosymbionts that modulate primary macrophage function and attenuate tumor growth by shifting the tumor microenvironment
Madsen, C. S.; Makela, A. V.; Maduka, C. V.; Greeson, E. M.; Tundo, A.; Ural, E.; Kulkarni, S. H.; Zarea, A.; Kiupel, M.; Sayadi, M.; Contag, C. H.
10.1101/2024.07.18.604190 — synthetic biology — Posted on 2024-07-19
2154 PRECLINICAL DEVELOPMENT OF A ROMIDEPSIN NANOPARTICLE DEMONSTRATES SUPERIOR TOLERABILITY AND EFFICACY IN MODELS OF HUMAN T-CELL LYMPHOMA AND LARGE GRANULAR LYMPHOCYTE LEUKEMIA
Pal, I.; Illendula, A.; Joyner, A.; Manavalan, J. S.; Deddens, T. M.; Sabzevari, A.; Damera, D. P.; Zuberi, S.; Marchi, E.; Fox, T. E.; Dunlap-Brown, M. E.; Jayappa, K. D.; Craig, J. W.; Loughran, T. P.; Feith, D. J.; O'Connor, O. A.
10.1101/2024.07.18.603379 — cancer biology — Posted on 2024-07-19
2156 Cost-effective DNA storage with DNA movable type
Wang, C.; Wei, D.; Wei, Z.; Yang, D.; Xing, J.; Wang, Y.; Wang, X.; Wang, P.; Ma, G.; Zhang, X.; Li, H.; Tang, C.; Hou, P.; Wang, J.; Gao, R.; Xie, G.; Li, C.; Ju, Y.; Wang, P.; Yue, L.; Zhao, Y.; Sheng, Y.; Xiao, J.; Niu, H.; Xu, S.; Duan, B.; Bu, D.; Tan, G.; Chen, F.
10.1101/2024.07.17.603163 — bioinformatics — Posted on 2024-07-19
2157 From spreadsheet lab data templates to knowledge graphs: A FAIR data journey in the domain of AMR research
Gadiya, Y.; Abbassi-Daloii, T.; Ioannidis, V.; Juty, N.; Stie Kallesoe, C.; Attwood, M.; Kohler, M.; Gribbon, P.; Witt, G.
10.1101/2024.07.18.604030 — bioinformatics — Posted on 2024-07-19
2160 Core Tri-fucosylation of Nematode N-glycans Requires Golgi α-mannosidase III Activity that Impacts Animal Growth and Behaviours
Kendler, J.; Woels, F.; Thapliyal, S.; Arcalis, E.; Gabriel, H.; Kubitschek, S.; Malzl, D.; Strobl, M. R.; Palmberger, D.; Luber, T.; Unverzagt, C.; Paschinger, K.; Glauser, D. A.; Wilson, I. B. H.; Yan, S.
10.1101/2024.07.18.600072 — biochemistry — Posted on 2024-07-19
2161 UK mosquitoes are competent to transmit Usutu virus at native temperatures
Pilgrim, J. D.; Metelmann, S.; Widlake, E.; Seechurn, N.; Vaux, A.; Mansfield, K. L.; Tanianis-Hughes, J.; Sherlock, K.; Johnson, N.; Medlock, J.; Baylis, M.; Blagrove, M. S.
10.1101/2024.07.19.604126 — ecology — Posted on 2024-07-19
2164 The Evolution and Epidemiology of H3N2 Canine Influenza Virus After 20 Years in Dogs
Wasik, B. R.; Damodaran, L.; Maltepes, M. A.; Voorhees, I. E.; Leutenegger, C. M.; Newbury, S.; Moncla, L. H.; Dalziel, B. D.; Goodman, L. B.; Parrish, C. R.
10.1101/2024.07.19.604289 — microbiology — Posted on 2024-07-19
2170 Multipath projection stereolithography (MPS) for 3D printing microfluidic devices
Soman, P.; Xiong, Z.; Geffert, Z. J.; Grutzmacher, J.; Wilderman, M.; Mohammadi, A.; Filip, A.; Li, Z.
10.1101/2024.07.18.604144 — bioinformatics — Posted on 2024-07-19
2171 Sodium butyrate is incorporated into central metabolism in fly head while inducing oxygen consumption increase
Müller-Eigner, A.; Gille, B.; Dethloff, F.; Meng, C.; Ludwig, C.; Heiker, J. T.; Giavalisco, P.; Peleg, S.
10.1101/2024.07.18.604059 — biochemistry — Posted on 2024-07-19
2172 Tbx1 stabilizes differentiation of the cardiopharyngeal mesoderm and drives morphogenesis in the pharyngeal apparatus
Lanzetta, O.; Bilio, M.; Liebig, J.; Jechow, K.; Ten, F. W.; Ferrentino, R.; Aurigemma, I.; Illingworth, E.; Conrad, C.; Lukassen, S.; Angelini, C.; Baldini, A.
10.1101/2024.07.16.603669 — developmental biology — Posted on 2024-07-19
2173 Permissive and instructive Hox codes govern limb positioning
Wang, Y.; Hintze, M.; Wang, J.; Petzsch, P.; Kohrer, K.; Tao, H.; Cheng, L.; Zhou, P.; Wang, J.; Liao, Z.; Qi, X.-F.; Cai, D.; Bartolomaeus, T.; Schilling, K.; Wilting, J.; Kuerten, S.; Koentges, G.; Patel, K.; Pu, Q.; Huang, R.
10.1101/2024.07.15.603511 — developmental biology — Posted on 2024-07-19
2175 Endothelial cell dysfunction and retinal arteriolar narrowing in young adults with elevated blood pressure
Tan, C.; Lewandowski, A. J.; Hanssen, H.; Streese, L.; Huckstep, O.; Fischer, R.; Alsharqi, M.; Mohamed, A.; Williamson, W.; Leeson, P.; Bertagnolli, M.
10.1101/2024.07.12.603349 — cell biology — Posted on 2024-07-19
2177 Incidence and multidrug resistance of Escherichia coli pathotypes on fresh vegetables and salads.
VAZQUEZ-QUINONES, C. R.; Rincon Guevara, M. A.; Natividad-Bonifacio, I.; Vazquez-Salinas, C.; Gonzalez-Marquez, H.
10.1101/2024.07.18.604175 — microbiology — Posted on 2024-07-19
2179 Antibacterial activity of tamoxifen derivatives against methicillin-resistant Staphylococcus aureus
Molina Panadero, I.; Falcon Torres, J.; Hmadcha, A.; Princiotto, S.; Cutarella, L.; Mori, M.; Dallavalle, S.; Christodoulou, M.; Smani, Y.
10.1101/2024.07.16.603795 — microbiology — Posted on 2024-07-19
2180 Antiparasitic effect of peptoids against Cryptosporidium parvum
Lamont, B.; Russell, B. M.; Suwanarusk, R.; Nielsen, J. E.; Sorensen, K.; Yung, D.; Barron, A.; Pletzer, D.; Muhsin-Sharafaldine, M.-R.
10.1101/2024.07.16.603782 — microbiology — Posted on 2024-07-19
2181 PicoCam: High-resolution 3D imaging of live animals and preserved specimens
Medina, J.; Irschick, D.; Epperly, K.; Cuban, D.; Elting, R.; Mansfield, L.; Lee, N.; Fermandes, A. M.; Garzon-Agudelo, F.; Rico-Guevara, A.
10.1101/2024.07.16.603742 — evolutionary biology — Posted on 2024-07-19
2183 TRGT-denovo: accurate detection of de novo tandem repeat mutations
Mokveld, T.; Dolzhenko, E.; Dashnow, H.; Nicholas, T. J.; Sasani, T.; van der Sanden, B.; Jadhav, B.; Pedersen, B.; Kronenberg, Z.; Tucci, A.; Sharp, A. J.; Quinlan, A. R.; Gilissen, C.; Hoischen, A.; Eberle, M. A.
10.1101/2024.07.16.600745 — bioinformatics — Posted on 2024-07-19
2184 Identification of novel myelodysplastic syndromes prognostic subgroups by integration of inflammation, cell-type composition, and immune signatures in the bone marrow
Gerlevik, S.; Seymen, N.; Hama, S.; Mumtaz, W.; Thompson, I. R.; Jalili, S. R.; Kaya, D. E.; Iacoangeli, A.; Pellagatti, A.; Boultwood, J.; Napolitani, G.; Mufti, G. J.; Karimi, M. M.
10.1101/2024.03.11.584361 — genomics — Posted on 2024-07-19
2185 The complete mitogenome of an unidentified Oikopleura species
Wibisana, J. N.; Plessy, C.; Dierckxsens, N.; Masunaga, A.; Miao, J.; Luscombe, N.
10.1101/2024.07.04.602139 — genomics — Posted on 2024-07-19
2191 NR2F2 is required in the embryonic testis for Fetal Leydig Cell development
Perea-Gomez, A.; Bellido Carreras, N.; Dhellemmes, M.; Tang, F.; Le Gallo, C.; Chaboissier, M.-C.
10.1101/2024.07.17.602099 — developmental biology — Posted on 2024-07-19
2193 Distinct tissue-niche localization and function of synovial tissue myeloid DC subsets in health, and in active and remission Rheumatoid Arthritis
MacDonald, L.; Elmesmari, A.; Somma, D.; Frew, J.; Di Mario, C.; Madhu, R.; Paoletti, A.; Simakou, T.; Hardy, O. M.; Tolusso, B.; Campobasso, D.; Perniola, S.; Gessi, M.; Gigante, M. R.; Petricca, L.; Bruno, D.; Coletto, L. A.; Benvenuto, R.; Isaacs, J. D.; Filby, A.; McDonald, D.; Sim, J. P. X.; Jamieson, N.; D'Agostino, M. A.; Wei, K.; Millar, N. L.; Milling, S.; McSharry, C.; Gremese, E.; Affleck, K.; Baker, K. F.; McInnes, I. B.; Otto, T. D.; Korsunsky, I.; Alivernini, S.; Kurowska-Stolarska, M.
10.1101/2024.07.17.600758 — immunology — Posted on 2024-07-19
2195 A ternary Neurexin-T178-PTPR complex represents a core-module of neuronal synapse organization
Thivaios, S.; Schwenk, J.; Brechet, A.; Boudkkazi, S.; Henneken, P.; Kocylowski, M. K.; Haupt, A.; Kaminski, D.; van den Broucke, J.-B.; Schreiner, D.; Schulte, U.; Sterky, F. H.; Yuzaki, M.; Scheiffele, P.; Fakler, B.
10.1101/2024.07.16.603715 — neuroscience — Posted on 2024-07-19
2198 Genetic variation in the species Arabidopsis thaliana reveals the existence of natural heat resilience factors for meiosis
Zhao, J.; Fu, H.; Wang, Z.; Zhang, M.; Liang, Y.; Cui, X.; Pan, W.; Ren, Z.; Wu, Z.; Zhang, Y.; Gui, X.; Huo, L.; Lei, X.; Wang, C.; Schnittger, A.; Pawlowski, W. P.; Liu, B.
10.1101/2024.07.16.603532 — plant biology — Posted on 2024-07-19
2199 Pectin methylesterase activity is required for RALF1 peptide signalling output
Roessling, A.-K.; Dunser, K.; Liu, C.; Lauw, S.; Rodriguez- Franco, M.; Kalmbach, L.; Barbez, E.; Kleine-Vehn, J.
10.1101/2023.08.18.553913 — plant biology — Posted on 2024-07-19
2200 Untargeted metabolomics reveals anion and organ-specific biochemistry of salinity tolerance in willow
Sas, E.; Fremont, A.; Gonzalez, E. J. B.; Sarrazin, M.; Barnabe, S.; Labrecque, M.; Brereton, n. J. B.; Pitre, F. E.
10.1101/2024.07.16.603755 — plant biology — Posted on 2024-07-19
2201 The microRNA156/SPL9 module mediates auxin response to facilitate apical hook maintenance in Arabidopsis
Pierdona, F. G.; Silva, A. J. M.; Vicente, M. H.; Taylor, L.; Pedmale, U. V.; Nogueira, F. T. S.
10.1101/2024.07.16.603710 — plant biology — Posted on 2024-07-19
2202 Mapping Genetic Interactions of All Paralogs in the Human Genome
Flister, M. J.; Verduzco, D.; Petiwala, S.; Ghekas, C.; Shi, X.; Lu, C.; Dezso, Z. J.
10.1101/2024.07.16.603642 — cancer biology — Posted on 2024-07-19
2203 Multiple allostery in the regulation of PDGFR beta kinase activities
Zhang, Y.; Wang, M.; Shao, G.; Shang, Q.; Dong, M.-Q.; Qin, X.; Mi, L.-Z.
10.1101/2024.06.06.597829 — biophysics — Posted on 2024-07-19
2205 SIngle cell level Genotyping Using scRna Data (SIGURD)
Grasshoff, M.; Kalmer, M.; Chaitan, N.; Kricheldorf, K.; Maurer, A.; Weiskirchen, R.; Koschmieder, S.; Costa, I. G.
10.1101/2024.07.16.603737 — bioinformatics — Posted on 2024-07-19
2206 Genomics-FM: Universal Foundation Model for Versatile andData-Efficient Functional Genomic Analysis
Ye, P.; Bai, W.; Ren, Y.; Li, W.; Qiao, L.; Liang, C.; Wang, L.; Cai, Y.; Sun, J.; Yang, Z.; Zheng, P.; Dong, N.; Chen, T.; Wang, Z.; Liu, X.; Ma, X.; Yan, H.; Wang, Z.; Wang, S.; Ouyang, W.
10.1101/2024.07.16.603653 — bioinformatics — Posted on 2024-07-19
2209 Potent pollen gene regulation by DNA glycosylases in maize
Zeng, Y.; Somers, J.; Bell, H. S.; Vejlupkova, Z.; Dawe, R. K.; Fowler, J. E.; Nelms, B.; Gent, J. I.
10.1101/2024.02.13.580204 — genetics — Posted on 2024-07-19
2210 Wheat TaNADPO promotes spot blotch resistance
Yuan, M.; Zeng, Q.; Hua, L.; Wu, J.; Zhao, S.; Li, M.; Ren, X.; Su, J.; Ren, Z.; Ma, L.; Liu, Z.; Wang, K.; Sun, M.; Yan, H.; Kang, Z.; Han, D.; Chen, S.; Wang, X.
10.1101/2024.07.16.602850 — genetics — Posted on 2024-07-19
2212 Experimental evolution of gene essentiality in bacteria
Bao, L.; Zhu, Z.; Ismail, A.; Zhu, B.; Anandan, V.; Whiteley, M.; Kitten, T.; Xu, P.
10.1101/2024.07.16.600122 — evolutionary biology — Posted on 2024-07-19
2213 Gene expression responses to environmental cues shed light on components of the migratory syndrome in butterflies
Shipilina, D.; Höök, L.; Näsvall, K.; Talla, V.; Palahi, A.; Parkes, E.; Vila, R.; Talavera, G.; Backström, N.
10.1101/2024.07.17.602486 — evolutionary biology — Posted on 2024-07-19
2216 Climate-driven vegetation characteristics shape phytophagous and carnivorous insect diversity in South African savannahs
Gaona, F. P.; Delabye, S.; Potocky, P.; Govorov, V.; Cuda, J.; Foxcroft, L. C.; Garlacz, R.; Hejda, M.; MacFadyen, S.; Pyrcz, T.; Pyskova, K.; Sedlacek, O.; Storch, D.; Pysek, P.; Tropek, R.
10.1101/2024.07.16.603689 — ecology — Posted on 2024-07-19
2217 Analysis of mixtures of birds and insects in weather radar data
Shi, X.; Drucker, J.; Chapman, J.; Sanchez-Herrera, M.; Dokter, A. M.
10.1101/2024.07.17.601450 — ecology — Posted on 2024-07-19
2218 Trap Spacing Protocols for Amazonian Dung Beetle Surveys
Hernandez Perez, E.; Aycart, P.; Chaboteaux, E.; Lopera Toro, A.; Forsyth, A.
10.1101/2024.07.16.603696 — ecology — Posted on 2024-07-19
2219 Oral citrate supplementation mitigates age-associated pathological intervertebral disc calcification in LG/J mice
Ottone, O. K.; Mundo, J. J.; Kwakye, B. N.; Slaweski, A.; John, J. A.; Wu, Q.; Connelly, M. A.; Niaziorimi, F.; van de Wetering, K.; Risbud, M.
10.1101/2024.07.17.604008 — cell biology — Posted on 2024-07-19
2220 Multiple clustered centrosomes in antigen-presenting cells foster T cell activation without MTOC polarization
Stoetzel, I.; Weier, A.-K.; Sarkar, A.; Som, S.; Konopka, P.; Mikova, E.; Boethling, J.; Homrich, M.; Schaedel, L.; Kazmaier, U.; Symeonidis, K.; Abdullah, Z.; Uderhardt, S.; Hons, M.; Paul, R.; Rieger, H.; Kiermaier, E.
10.1101/2024.07.18.604057 — cell biology — Posted on 2024-07-19
2221 Alternative splicing in mechanically stretched podocytes as a model of glomerular hypertension
Mattias, F.; Tsoy, O.; Hammer, E.; Gress, A.; Simm, S.; Lio, C. T.; Ameling, S.; Kalinina, O.; Amann, K.; Dreher, L.; Wenzel, U.; Endlich, K.; Baumbach, J.; Voelker, U.; Endlich, N.; Kliewe, F.
10.1101/2024.07.17.603550 — cell biology — Posted on 2024-07-19
2222 STANDARDISED FLOW CYTOMETRIC PROCEDURE FOR DEEP CHARACTERIZATION OF NANOPARTICLES
Tirelli, V.; Grasso, F.; Barreca, V.; Polignano, D.; gallinaro, a.; Cara, A.; Sargiacomo, M.; Fiani, M. L.; Sanchez, M.
10.1101/2024.07.18.604065 — cell biology — Posted on 2024-07-19
2224 Endomucin regulates the endothelial cytoskeleton independent of VEGF
Moon, J.; Chaudhary, S.; Rodriguez Martinez, L.; Hu, Z.; D'Amore, P. A.
10.1101/2024.07.17.603969 — cell biology — Posted on 2024-07-19
2228 Mammalian D-Cysteine controls insulin secretion in the pancreas
Roychaudhuri, R.; West, T.; Bhattacharya, S.; Saavedra, H.; Albacarys, L.; Gadalla, M. M.; Amzel, L. M.; Yang, P.; Snyder, S. H.
10.1101/2022.05.17.492243 — biochemistry — Posted on 2024-07-19
2229 PLINDER: The protein-ligand interactions dataset and evaluation resource
Durairaj, J.; Adeshina, Y.; Cao, Z.; Zhang, X.; Oleinikovas, V.; Duignan, T.; McClure, Z.; Robin, X.; Kovtun, D.; Rossi, E.; Zhou, G.; Veccham, S.; Isert, C.; Peng, Y.; Sundareson, P.; Akdel, M.; Corso, G.; Stärk, H.; Carpenter, Z.; Bronstein, M.; Kucukbenli, E.; Schwede, T.; Naef, L.
10.1101/2024.07.17.603955 — biochemistry — Posted on 2024-07-19
2235 High-motility pro-tumorigenic monocytes drive macrophage enrichment in the tumor microenvironment
Du, W.; Zhou, B.; Forjaz, A.; Shin, S. M.; Wu, F.; Crawford, A. J.; Nair, P. R.; Johnston, A. C.; West-Foyle, H.; Tang, A.; Kim, D.; Fan, R.; Kiemen, A. L.; Wu, P.-H.; Phillip, J. M.; Ho, W. J.; Sanin, D. E.; Wirtz, D.
10.1101/2024.07.16.603739 — immunology — Posted on 2024-07-18
2237 Stepping dynamics of dynein characterized by MINFLUX
Slivka, J.; Gleave, E.; Wijewardena, D. P.; Canty, J. T.; Selvin, P. R.; Carter, A. P.; Yildiz, A.
10.1101/2024.07.16.603667 — biophysics — Posted on 2024-07-18
2238 A Cost-effective, High-throughput, Highly Accurate Genotyping Method for Outbred Populations
Chen, D.; Chitre, A. S.; Nguyen, K.-M. H.; Cohen, K. A.; Peng, B. F.; Ziegler, K. S.; Okamoto, F.; Lin, B.; Johnson, B. B.; Sanches, T. M.; Cheng, R.; Polesskaya, O.; Palmer, A. A.
10.1101/2024.07.17.603984 — genetics — Posted on 2024-07-18
2240 Induced degradation of SNAP-fusion proteins
Abraham Pol, S.; Liljenberg, S.; Barr, J.; Simon, G.; Wong-Dilworth, L.; Paterson, D. L.; Berishvili, V. P.; Bottanelli, F.; Kaschani, F.; Kaiser, M.; Pettersson, M.; Hellerschmied, D.
10.1101/2024.07.18.603056 — cell biology — Posted on 2024-07-18
2241 A Field-Deployable Arsenic Sensor Integrating Bacillus Megaterium with CMOS Technology
Hu, C. Y.; McManus, J. B.; Aghlmand, F.; Larsson, E. M.; Emami, A.; Murray, R. M.
10.1101/2024.07.18.604150 — synthetic biology — Posted on 2024-07-18
2243 Microbial metabolomics' latest SICRIT: Soft ionization by Chemical Reaction in-Transfer mass spectrometry
McAtamney, A.; Ferranti, A.; Ludvik, D. A.; Yildiz, F. H.; Mandel, M. J.; Hayward, T.; Sanchez, L.
10.1101/2024.07.17.604007 — biochemistry — Posted on 2024-07-18
2246 CACHE Challenge #1: targeting the WDR domain of LRRK2, a Parkinson's Disease associated protein.
Ackloo, S.; Arrowsmith, C. H.; Ban, F.; Barden, C. J.; Beck, H.; Beranek, J.; Berenger, F.; Bolotokova, A.; Bret, G.; Breznik, M.; Carosati, E.; Chau, I.; Chen, Y.; Cherkasov, A.; Della Corte, D.; Denzinger, K.; Dong, A.; Draga, S.; Dunn, I.; Edfeldt, K.; Edwards, A.; Eguida, M.; Eisenhuth, P.; Friedrich, L.; Fuerll, A.; Gardiner, S.; Gentile, F.; Ghiabi, P.; Gibson, E.; Glavatskikh, M.; Gorgulla, C.; Guenther, J.; Gunnarsson, A.; Guseve, F.; Gutkin, E.; Hillisch, A.; Hoffer, L.; Hogner, A.; Irwin, J. J.; Isayev, O.; Ivanova, A.; Jacquemard, C.; Jarrett, A. J.; Jensen, J. H.; Kireev, D.; Klebe
10.1101/2024.07.18.603797 — biochemistry — Posted on 2024-07-18
2248 Structural basis for the interaction between the bacterial cell division proteins FtsZ and ZapA
Fujita, J.; Hibino, K.; Kagoshima, G.; Kamimura, N.; Kato, Y.; Uehara, R.; Namba, K.; Uchihashi, T.; Matsumura, H.
10.1101/2024.07.18.604045 — molecular biology — Posted on 2024-07-18
2249 Histone Tetrasome Dynamics Affects Chromatin Transcription
Shi, X.; Fedulova, A.; Kotova, E.; Maluchenko, N.; Armeev, G.; Chen, Q.; Prasanna, C.; Sivkina, A.; Feofanov, A.; Kirpichnikov, M.; Nordenskiold, L.; Shaytan, A. K.; Studitsky, V.
10.1101/2024.07.18.604164 — molecular biology — Posted on 2024-07-18
2252 FASTKD5 processes mitochondrial pre-mRNAs at non-canonical cleavage sites
Antonicka, H.; Weraarpachai, W.; Vuckovic, A.; Hillen, H. S.; Shoubridge, E. A.
10.1101/2024.07.18.603998 — molecular biology — Posted on 2024-07-18
2254 Stabilized dengue virus 2 envelope subunit vaccine redirects the neutralizing antibody response to all E-domains
Thiono, D. J.; Samaras, D. L.; Phan, T.; Zhu, D. R.; Shah, R. P.; Castillo, I. N.; Forsberg, L. J.; Premkumar, L.; Baric, R. S.; Tian, S.; Kuhlman, B.; de Silva, A. M.
10.1101/2024.07.18.604114 — microbiology — Posted on 2024-07-18
2255 A conjugative plasmid exploits flagella rotation as a cue to facilitate its transfer
Bhattacharya, S.; Bejerano-Sagie, M.; Ravins, M.; Zeroni, L.; Kaur, P.; Gopu, V.; Rosenshine, I.; Ben-Yehuda, S.
10.1101/2024.07.18.604039 — microbiology — Posted on 2024-07-18
2257 Global survey of secondary metabolism in Aspergillus niger via activation of specific transcription factors
Semper, C.; Pham, T. T. M.; Ram, S.; Palys, S.; Evdokias, G.; Ouedraogo, J.-P.; Moisan, M.-C.; Geoffrion, N.; Reid, I.; Di Falco, M.; Bailey, Z.; Tsang, A.; Benoit-Gelber, I.; Savchenko, A.
10.1101/2024.07.18.604165 — microbiology — Posted on 2024-07-18
2258 Identifying essential genes in Schaalia odontolytica using a highly-saturated transposon library
Bedree, J. K.; Bourgeois, J.; Balani, P.; Cen, L.; Hendrickson, E.; Kerns, K.; Camilli, A.; McLean, J. S.; He, X.
10.1101/2024.07.17.604004 — microbiology — Posted on 2024-07-18
2260 When is microbial strain sharing evidence for transmission?
Debray, R. R.; Dickson, C. C.; Webb, S. E.; Archie, E. A.; Tung, J.
10.1101/2024.07.18.604082 — microbiology — Posted on 2024-07-18
2261 The role of stomatin-like protein (STOML) in Plasmodium falciparum
Verhoef, J. M. J.; Bekkering, E. T.; Boshoven, C.; Hannon, M.; Proellochs, N.; Spruijt, C. G.; Kooij, T. W. A.
10.1101/2024.07.18.604071 — microbiology — Posted on 2024-07-18
2264 Rapid protein evolution by few-shot learning with a protein language model
Jiang, K.; Yan, Z.; Bernardo, M. D.; Sgrizzi, S. R.; Villiger, L.; Kayabolen, A.; Kim, B.; Carscadden, J. K.; Hiraizumi, M.; Nishimasu, H.; Gootenberg, J. S.; Abudayyeh, O. O.
10.1101/2024.07.17.604015 — bioengineering — Posted on 2024-07-18
2265 Sensing endogenous RNA in living human cells using a CRISPR-activated protease
Blumenstock, K.; Hoch, A.; Hinterlang, L. D.; Caroline, F.; Schneberger, N.; Hagelueken, G.; Schmid-Burgk, J. L.
10.1101/2024.07.17.603943 — bioengineering — Posted on 2024-07-18
2269 Systematic Targeting of Protein Complexes with Molecular COUPLrs
Yang, D.; Harry, S.; Chong, H.; Zhang, E.; Nordenfelt, N.; Chen, N.; Lee, C.; Kaluziak, S.; Codd, E.; Trivedi, S.; Gohar, M.; McKnight, G.; Mitchell, D.; Ge, M.; Gao, C.; Holmes, Z.; Yang, W.; Smith, A.; Carlin, A.; Lazarov, M.; Khandelwal, N.; Takahashi, M.; Zhang, S.; Leong, H.; Martinez Luna, H.; Chearavanont, Z.; Emonds, K.; Popoola, G.; Barakat, I.; Onozato, M.; Mahamdeh, M. S. S.; Fujino, T.; Seo, H.-S.; Dhe-Paganon, S.; Sun, Z.-Y.; Heffron, G.; Hata, A.; Soberman, R.; Liau, B.; Iafrate, A. J.; bar-peled, l.
10.1101/2024.07.16.603666 — systems biology — Posted on 2024-07-18
2276 Trained Immunity Causes Myeloid Cell Hypercoagulability
Rehill, A. M.; McCluskey, S.; Ledwith, A. E.; Ryan, T. A.; Leon, G.; Charles-Messance, H.; Gilbert, E. H.; Day, E. A.; McMahon, C.; O'Donnell, J. S.; Curtis, A. M.; O'Neill, L. A.; Sheedy, F. J.; Preston, R. J.
10.1101/2024.07.16.603679 — immunology — Posted on 2024-07-18
2277 Multimodal MEG and microstructure-MRI investigations of the human hippocampal scene network
Read, M.-L.; Hodgetts, C. J.; Lawrence, A. D.; Evans, C. J.; Singh, K. D.; Umla-Runge, K.; Graham, K. S.
10.1101/2024.07.16.603546 — neuroscience — Posted on 2024-07-18
2280 Cognitive hyperplasticity drives insomnia
Huang, S.; Piao, C.; Zhao, Z.; Beuschel, C. B.; Turrel, O.; Toppe, D.; Sigrist, S. J.
10.1101/2024.07.16.603670 — neuroscience — Posted on 2024-07-18
2281 A universal cannabinoid CB1 and CB2 receptor TR-FRET kinetic ligand binding assay.
Borrega-Roman, L.; Hoare, B. L.; Kosar, M.; Sarott, R. C.; Patej, K. J.; Bouma, J.; Scott-Dennis, M.; Koers, E. J.; Gazzi, T.; Mach, L.; Barrondo, S.; Salles, J.; Guba, W.; Kusznir, E.; Nazare, M.; Rufer, A. C.; Grether, U.; Heitman, L. H.; Carreira, E. M.; Sykes, D. A.; Veprintsev, D. B.
10.1101/2024.07.16.603654 — pharmacology and toxicology — Posted on 2024-07-18
2282 An epidemiological description of rabies outbreaks in Zambia from 2013 to 2023.
kachinda, w.; Banda, H.; Hamukale, A.; Makungu, C.; Ngoma, M.; Chazya, R.; Mataa, L.; Mulenga, C.; Banda, J. B.; Muleya, W.; Sialubanje, C.; Banda, D.; Sinyange, N.
10.1101/2024.07.16.603659 — pathology — Posted on 2024-07-18
2283 Integrated multiomic profiling reveals SWI/SNF subunit-specific pathway alterations and targetable vulnerabilities
Bretones-Santamarina, J.; Astier, C.; Garrido, M.; Colmet-Daage, L.; Roumeliotis, T. I.; Anthony, E.; Pardo, M.; Chasseriaud, M.; Gestraud, P.; Ngo, C.; Morel, D.; Chabanon, R.; Chaudhary, J. S.; Del Nery, E.; Postel-Vinay, S.; Ballesta, A.
10.1101/2024.07.16.603530 — cancer biology — Posted on 2024-07-18
2285 Normalization strategies for lipidome data in cell line panels
Leegwater, H.; Zhang, Z.; Zhang, X.; Hankemeier, T.; Harms, A. C.; Zweemer, A. J. M.; Le Devedec, S. E.; Kindt, A.
10.1101/2024.07.16.600977 — bioinformatics — Posted on 2024-07-18
2298 Mathematical model of transcription loss due to accumulated DNA damage
Raseta, M.; Grint, J. v. d.; Dealy, S.; Chang, J.; Hoeijmakers, J.; Pothof, J.
10.1101/2024.07.15.603615 — systems biology — Posted on 2024-07-18
2299 Insights into the role of root exudates in bacteriophage infection dynamics
Novak, V.; van Winden, M. C. M.; Harwood, T. V.; Neurath, R.; Kosina, S. M.; Louie, K. B.; Sullivan, M. B.; Roux, S.; Zengler, K.; Mutalik, V. K.; Northen, T. R.
10.1101/2024.07.15.603626 — plant biology — Posted on 2024-07-18
2300 An Adipo-Pulmonary Axis Mediated by FABP4 Hormone Defines a Therapeutic Target Against Obesity-Induced Airway Disease
Burak, M. F.; Tuncman, G.; Ayci, A. N.; Chetal, K.; Lee Seropian, G. Y.; Inouye, K. E.; Lai, Z. W.; Dagtekin, N.; Sadreyev, R. E.; Israel, E.; Hotamisligil, G. S.
10.1101/2024.07.15.603433 — physiology — Posted on 2024-07-18
2301 Classification of dinosaur footprints using machine learning
Jones, M.; Lallensack, J. N.; Jarman, I.; Falkingham, P.; Siekmann, I.
10.1101/2024.07.15.603597 — paleontology — Posted on 2024-07-18
2302 YAP1 is a key regulator of EWS::FLI1-dependent malignant transformation upon IGF-1 mediated reprogramming of bone mesenchymal stem cells
Kovar, H.; Noorizadeh, R.; Sax, B.; Javaheri, T.; Radic Sarikas, B.; Fock, V.; Kauer, M.; Bykov, A.; Suresh, V.; Schlederer, M.; Kenner, L.; Weber, G.; Mikulits, W.; Halbritter, F.; Moriggl, R.
10.1101/2024.07.15.603565 — cancer biology — Posted on 2024-07-18
2306 Peptide Coated Polycaprolactone-Benzalkonium Chloride Nanocapsules for Targeted Drug Delivery to the Pancreatic β-Cell
Collins, J.; Barra, J. M.; Holcomb, K.; Ocampo, A.; Fremin, A.; Akolade, J.; Kratz, A.; Hays, J. K.; Shilleh, A.; Hodson, D. J.; Broichhagen, J. J.; Russ, H. A.; Farnsworth, N. L.
10.1101/2024.07.15.603612 — bioengineering — Posted on 2024-07-18
2310 Automated Skin Lesion Detection and Prevalence Estimation in Tamanend's Bottlenose Dolphins
Murphy, C. J.; Collier, M. A.; Jacoby, A.-M.; Patterson, E. M.; Wallen, M. M.; Mann, J.; Bansal, S.
10.1101/2024.07.15.603578 — ecology — Posted on 2024-07-18
2312 Branched actin networks in innate immune cells mediate host microbiota homeostasis.
Vasconcellos, L. R.; Huang, S. C. M.; Suarez-Bonnet, A.; Priestnall, S.; Varsani-Brown, S.; Winder, M. L.; Shah, K.; Kogata, N.; Stockinger, B.; Way, M.
10.1101/2024.07.18.604111 — immunology — Posted on 2024-07-18
2313 Resistance to age-related hearing loss in the echolocating big brown bat (Eptesicus fuscus)
Capshaw, G.; Diebold, C. A.; Adams, D. M.; Rayner, J.; Wilkinson, G. S.; Moss, C. F.; Lauer, A. M.
10.1101/2024.07.15.603592 — neuroscience — Posted on 2024-07-18
2317 Modeling the effect of daytime duration on the biosynthesis of terpenoid precursors
Basallo, O.; Lucido, A.; Sorribas, A.; Marin-Sanguino, A.; Martinez, E.; Vilaprinyo, E.; Eleiwa, A.; Alves, R.
10.1101/2024.07.15.603555 — systems biology — Posted on 2024-07-18
2318 Additive and partially dominant effects contribute to crop heterosis
Dan, Z.; Chen, Y.; Zhou, W.; Xu, Y.; Huang, J.; Chen, Y.; Meng, J.; Yao, G.; Huang, W.
10.1101/2024.07.16.603817 — plant biology — Posted on 2024-07-18
2321 Exploring Harmala Alkaloids as Novel Antimalarial Agents against Plasmodium falciparum through Bioinformatics Approaches
Dipto, K. Z.; Shariar, R.; Saha, C. K.; Huzaifa, A.; Robin, T. B.; Patil, R. B.; Alam, M. T.; Rafi, M. I. H.; Faruk, A. Z.; Moin, A. T.; Zinnah, K. M. A.; Hasanuzzaman, M.; Islam, T.
10.1101/2024.07.17.603828 — bioinformatics — Posted on 2024-07-18
2323 Butyrate as a growth factor of Clostridium acetobutylicum
Seo, H.; Capece, S.; Hill, J. D.; Otten, J.; PAPOUTSAKIS, E. T.
10.1101/2024.07.15.603595 — bioengineering — Posted on 2024-07-18
2324 Plant functional types and tissue stoichiometry explain nutrient transfer in common arbuscular mycorrhizal networks of temperate grasslands
Dawson, H. R.; Shek, K. L.; Maxwell, T. M.; Reed, P. B.; Bomfim, B.; Bridgham, S.; Bohannan, B.; Silva, L. C. R.
10.1101/2022.10.05.511035 — ecology — Posted on 2024-07-18
2326 'Off-pore' nucleoporins relocalize heterochromatic breaks through phase separation
Merigliano, C.; Ryu, T.; See, C. D.; Caridi, C. P.; Li, X.; Butova, N.; Reynolds, T.; Deng, C.; Chenoweth, D. M.; Capelson, M.; Chiolo, I.
10.1101/2023.12.07.570729 — cell biology — Posted on 2024-07-18
2327 Acoustically evoked K-complexes together with sleep spindles boost verbal declarative memory consolidation in healthy adults
Leach, S.; Krugliakova, E.; Sousouri, G.; Snipes, S.; Scorucak, J.; Schuehle, S.; Mueller, M.; Ferster, M. L.; Da Poian, G.; Karlen, W.; Huber, R.
10.1101/2023.06.29.546822 — neuroscience — Posted on 2024-07-18
2328 Stimulus invariant aspects of the retinal code drive discriminability of natural scenes
Hoshal, B.; Holmes, C. M.; Bojanek, K.; Salisbury, J. M.; Berry, M. J.; Marre, O.; Palmer, S.
10.1101/2023.08.08.552526 — neuroscience — Posted on 2024-07-18
2330 Appearance of green tea compounds in plasma following green tea consumption is modulated by the gut microbiome in mice
Sterrett, J. D.; Quinn, K. D.; Doenges, K. A.; Nusbacher, N.; Levens, C. L.; Armstrong, M. L.; Reisdorph, R. M.; Smith, H.; Saba, L. M.; Kuhn, K. A.; Lozupone, C.; Reisdorph, N.
10.1101/2024.07.11.603097 — systems biology — Posted on 2024-07-18
2331 Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning
Estevam, G. O.; Linossi, E. M.; Rao, J.; Macdonald, C. B.; Ravikumar, A.; Chrispens, K. M.; Capra, J. A.; Coyote-Maestas, W.; Pimentel, H.; Collisson, E. A.; Jura, N.; Fraser, J. S.
10.1101/2024.07.16.603579 — cancer biology — Posted on 2024-07-18
2332 RNAGEN: A generative adversarial network-based model to generate synthetic RNA sequences to target proteins
Ozden, F.; Barazandeh, S.; Akboga, D.; Shokoueian Tabrizi, S.; Seker, U. O. S.; Cicek, A. E.
10.1101/2023.07.11.548246 — bioinformatics — Posted on 2024-07-18
2335 Exploring TAS2R46 Biomechanics through Molecular Dynamics and Network Analysis
Cannariato, M.; Fanunza, R.; Zizzi, E. A.; Miceli, M.; Di Benedetto, G.; Deriu, M. A.; Pallante, L.
10.1101/2023.11.21.568072 — bioengineering — Posted on 2024-07-18
2336 A differential requirement for ciliary transition zone proteins in human and mouse neural progenitor fate specification
Wiegering, A.; Anselme, I.; Brunetti, L.; Metayer-Derout, L.; Calderon, D.; Thomas, S.; Nedelec, S.; Eschstruth, A.; Serpieri, V.; catala, m.; Antoniewski, C.; Schneider-Maunoury, S.; STEDMAN, A.
10.1101/2024.02.28.582477 — developmental biology — Posted on 2024-07-18
2337 Pseudocobalamin production and use in marine Synechococcus cultures and communities
Bannon, C. C.; Soto, M. A.; Rowland, E.; Chen, N.; Gleason, A.; Devred, E.; LaRoche, J.; Bertrand, E. M.
10.1101/2024.04.01.587587 — microbiology — Posted on 2024-07-18
2338 Rhythmic sampling of multiple decision alternatives in the human brain
Siems, M.; Cao, Y.; Tohidi-Moghaddam, M.; Donner, T. H.; Tsetsos, K.
10.1101/2023.12.08.570734 — neuroscience — Posted on 2024-07-18
2341 A high-light tolerant alga from the desert is protected from oxidative stress by NPQ-independent responses
Levin, G.; Yasmin, M.; Liran, O.; Hanna, R.; Kleifeld, O.; Horev, G.; Wollman, F.-A.; Schuster, G.; Nawrocki, W. J.
10.1101/2024.06.10.598256 — plant biology — Posted on 2024-07-18
2348 Primary auditory thalamus relays directly to cortical layer 1 interneurons
Vattino, L. G.; MacGregror, C. P.; Liu, C. J.; Sweeney, C. G.; Takesian, A. E.
10.1101/2024.07.16.603741 — neuroscience — Posted on 2024-07-18
2349 Identifying Artifacts from Large Library Docking
Wu, Y.; Liu, F.; Glenn, I.; Fonseca-Valencia, K.; Paris, L.; Xiong, Y.; Jerome, S. V.; Brooks, C. L.; Shoichet, B. K.
10.1101/2024.07.17.603966 — biophysics — Posted on 2024-07-18
2350 Metabolic phenotyping of healthy and diseased human RPE cells
Rizwan, S.; Toothman, B.; Li, B.; Engel, A. J.; Lim, R. R.; Niernberger, S.; Lu, J.; Ratcliff, C.; Xiang, Y.; Eminhizer, M.; Chao, J. R.; Du, J.
10.1101/2024.02.28.582405 — biochemistry — Posted on 2024-07-18
2351 Temporal and spatial variability in availability bias has consequences for marine bird abundance estimates during the non-breeding season
Dunn, R. E.; Duckworth, J.; O'Brien, S.; Furness, R. W.; Buckingham, L.; Daunt, F.; Bogdanova, M. I.; Green, J. A.
10.1101/2024.03.13.584773 — ecology — Posted on 2024-07-18
2352 Control of lumen geometry and topology by the interplay between pressure and cell proliferation rate in pancreatic organoids
Lee, B. H.; Fuji, K.; Petzold, H.; Seymour, P. A.; Yennek, S.; Schewin, C.; Lewis, A.; Riveline, D.; Hiraiwa, T.; Sano, M.; Grapin-Botton, A.
10.1101/2024.05.29.596462 — developmental biology — Posted on 2024-07-18
2353 Overexpression of enhanced yellow fluorescent protein fused with Channelrhodopsin-2 causes contractile dysfunction in skeletal muscle
Lamia, S. N. E.; Davis, C. S.; Macpherson, P. C. D.; Willingham, B.; Zhang, Y.; Liu, C.; Iannucci, L.; Ganji, E.; Harden, D.; Bhattacharya, I.; Abraham, A. C.; Brooks, S. V.; Glancy, B.; Killian, M. L.
10.1101/2024.06.06.597782 — physiology — Posted on 2024-07-18
2354 A heterogeneous pool of tumor precursor cells with self-replenishing and tumor-originating properties in Chronic Lymphocytic Leukemia
Budeus, B.; Dampmann, M.; Kibler, A.; Fassbender, B.; Brauser, M.; Bronischewski, K.; Homp, E.; Taudien, S.; Johansson, P.; Bloehdorn, J.; Stilgenbauer, S.; von Tresckow, J.; Duerig, J.; Reinhardt, H. C.; Kueppers, R.; Dietrich, S.; Seifert, M.
10.1101/2022.05.04.490383 — cancer biology — Posted on 2024-07-18
2355 Detection of changes in membrane potential by magnetic resonance imaging
Min, K.; Chung, S.; Lee, S.-K.; Lee, J.; Toi, P. T.; Kim, D.; Lee, J. S.; Park, J.-Y.
10.1101/2024.04.02.587661 — biophysics — Posted on 2024-07-18
2356 Mechanism of host cell invasion by Leishmania through KMP-11 mediated cholesterol-transport and membrane phase transition
Chattopadhyay, K.; Sannigrahi, A.; Ghosh, S.; Jana, P.; Jawed, J. J.; Pradhan, S.; Majumdar, S.; Roy, S.; Karmakar, S.; Mukherjee, B.
10.1101/2024.07.15.603533 — biophysics — Posted on 2024-07-18
2357 CellPie: a scalable spatial transcriptomics factor discovery method via joint non-negative matrix factorization
Georgaka, S.; Morgans, W. G.; Zhao, Q.; Sanchez Martinez, D.; Ali, A.; Ghafoor, M.; Baker, S. M.; Bristow, R.; Iqbal, M.; Rattray, M.
10.1101/2023.09.29.560213 — bioinformatics — Posted on 2024-07-18
2359 On the synergy between myelin proteins P0, MBP, and P2 in peripheral nerve major dense line formation
Krokengen, O. C.; Raasakka, A.; Klenow, M. B.; Pal, A.; Hetland, O.; Mularski, A.; Ruskamo, S.; Pedersen, J. S.; Simonsen, A. C.; Kursula, P.
10.1101/2024.07.15.603506 — biochemistry — Posted on 2024-07-18
2360 Constant surface area-to-volume ratio during cell growth as a design principle in mammalian cells
Wu, W.; Lam, A. R.; Suarez, K.; Smith, G. N.; Duquette, S. M.; Yu, J.; Mankus, D.; Bisher, M.; Lytton-Jean, A.; Manalis, S. R.; Miettinen, T. P.
10.1101/2024.07.02.601447 — cell biology — Posted on 2024-07-18
2362 Synthesis of geometrically realistic and watertight neuronal ultrastructure manifolds for in silico modeling
Abdellah, M.; Foni, A.; Garcia Cantero, J. J.; Roman Guerrero, N.; Boci, E.; Fleury, A.; Coggan, J. S.; Keller, D.; Planas, J.; Courcol, J.-D.; Khazen, G.
10.1101/2024.03.11.584388 — neuroscience — Posted on 2024-07-18
2366 Targeting fatty acid synthase suppresses tumor development in NF2/CDKN2A-deficient malignant pleural mesothelioma
Karnan, S.; Ota, A.; Hasan, M. N.; Murakami, H.; Rahman, M. L.; Wahiduzzaman, M.; Shihan, M. T. A.; Jahan, N.; Vu, L. Q.; Hanamura, I.; Inoko, A.; Riku, M.; Ito, H.; Kaneko, Y.; Lin, Y.; Hyodo, T.; Konishi, H.; Tsuzuki, S.; Hosokawa, Y.
10.1101/2024.07.14.603191 — cancer biology — Posted on 2024-07-18
2368 Identification of spatial homogeneous regions in tissues with concordex
Jackson, K. C.; Booeshaghi, A. S.; Galvez-Merchan, A.; Moses, L.; Chari, T.; Kim, A.; Pachter, L.
10.1101/2023.06.28.546949 — bioinformatics — Posted on 2024-07-18
2369 Ribosomal RNA methylation by GidB modulates discrimination of mischarged tRNA
Bi, Z.; Chen, Y.-X.; Young, I. D.; Su, H.; Chen, Y.; Hong, J.; Fraser, J. S.; Javid, B.
10.1101/2021.03.02.433644 — molecular biology — Posted on 2024-07-18
2372 Fixational Eye Movements Enhance the Precision of Visual Information Transmitted by the Primate Retina
Wu, E. G.; Brackbill, N.; Rhoades, C. E.; Kling, A.; Gogliettino, A. R.; Shah, N. P.; Sher, A.; Litke, A. M.; Simoncelli, E. P.; Chichilnisky, E. J.
10.1101/2023.08.12.552902 — neuroscience — Posted on 2024-07-18
2374 Expanding salivary biomarker detection by creating a synthetic neuraminic acid sensor via chimeragenesis
Verzino, S. J.; Priyev, S. A.; Sanchez Estrada, V. A.; Crowley, G. X.; Rutkowski, A.; Lam, A. C.; Nazginov, E. S.; Kotemelo, P.; Bacelo, A.; Sukhram, D. T.; Vazquez, F. X.; Fernandez Juarez, J.
10.1101/2024.06.13.598939 — synthetic biology — Posted on 2024-07-18
2375 Dual expansion routes likely underlie the present-day population structure in a Parnassius butterfly across the Japanese Archipelago
Tamura, H.; Noda, T.; Hayashi, M.; Fujii, Y.; Iwata, N.; Yokota, Y.; Murata, M.; Tatematsu, C.; Tera, A.; Ono, K.; Yokoi, K.; Kato, T.; Okamoto, T.; Tsuchida, K.
10.1101/2024.07.16.603823 — molecular biology — Posted on 2024-07-17
2379 The Bordetella effector protein BteA induces host cell death by disruption of calcium homeostasis
Zmuda, M.; Sedlackova, E.; Pravdova, B.; Cizkova, M.; Cerny, O.; Allsop, T. R.; Grousl, T.; Malcova, I.; Kamanova, J.
10.1101/2024.07.17.603939 — microbiology — Posted on 2024-07-17
2381 Cell division protein A (CdpA) assembles and anchors the two FtsZ rings at midcell in haloarchaea
Liao, Y.; Shinde, V. D.; Hu, D.; Xu, Z.; Soderstrom, B.; Michie, K. A.; Duggin, I. G.
10.1101/2024.07.17.603854 — microbiology — Posted on 2024-07-17
2382 Northern peatland microbial networks exhibit resilience to warming and acquire electron acceptor from soil organic matter
Duchesneau, K.; Aldeguer Riquelme, B.; Petro, C.; Makke, G.; Green, M.; Tfaily, M.; Wilson, R.; Roth, S. W.; Johnston, E. R.; Kluber, L. A.; Schadt, C. W.; Chanton, J. P.; Hanson, P. J.; Tringe, S.; Eloe-Fadrosh, E.; Glavina Del Rio, T.; Konstantinidis, K. T.; Kostka, J. E.
10.1101/2024.07.17.603906 — microbiology — Posted on 2024-07-17
2384 Prkra is the double-stranded RNA sensor to mediate an embryonic integrated stress response
Lu, T.; Ma, P.; Chen, A.; Fang, H.; Xu, J.; Wang, M.; Su, L.; Wang, S.; Zhang, Y.; Wang, J.; Yang, B.; Shi, D.-L.; Zhou, Y.; Gong, Q.; Liu, X.; Mao, B.; Shao, M.
10.1101/2024.07.16.603655 — immunology — Posted on 2024-07-17
2387 PLINDER: The protein-ligand interactions dataset and evaluation resource
Durairaj, J.; Adeshina, Y.; Cao, Z.; Zhang, X.; Oleinikovas, V.; Duignan, T.; McClure, Z.; Robin, X.; Kovtun, D.; Rossi, E.; Zhou, G.; Veccham, S.; Isert, C.; Peng, Y.; Sundareson, P.; Akdel, M.; Corso, G.; Stärk, H.; Carpenter, Z.; Bronstein, M.; Kucukbenli, E.; Schwede, T.; Naef, L.
10.1101/2024.07.17.603955 — biochemistry — Posted on 2024-07-17
2392 Evolution of SARS-CoV-2 spike trimers towards optimized heparan sulfate cross-linking and inter-chain mobility
Froese, J.; Mandalari, M.; Civera, M.; Elli, S.; Pagani, I.; Vicenzi, E.; Garcia-Monge, I.; Di Iorio, D.; Frank, S.; Bisio, A.; Lenhart, D.; Gruber, R.; Yates, E. A.; Richter, R. P.; Guerrini, M.; Wegner, S. V.; Grobe, K.
10.1101/2024.07.17.603909 — molecular biology — Posted on 2024-07-17
2393 Virological characteristics of the SARS-CoV-2 KP.3.1.1 variant
Kaku, Y.; Uriu, K.; Okumura, K.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Ito, J.; Sato, K.
10.1101/2024.07.16.603835 — microbiology — Posted on 2024-07-17
2395 Exploring the impact of digestive physicochemical parameters of adults and infants on the pathophysiology of Cryptosporidium parvum using the dynamic TIM-1 gastrointestinal model
Tottey, J.; Etienne-Mesmin, L.; Chalancon, S.; Sausset, A.; Denis, S.; Mazal, C.; Blavignac, C.; Salle, G.; Laurent, F.; Blanquet-Diot, S.; Lacroix-Lamande, S.
10.1101/2024.07.17.603888 — microbiology — Posted on 2024-07-17
2396 Clostridioides difficile colonization is not mediated by bile salts and requires Stickland fermentation of proline in an in vitro model of infection
Huang, X.; Johnson, A. E.; Auchtung, T. A.; McCullough, H. C.; Lerma, A. I.; Haidacher, S. J.; Hoch, K. M.; Horvath, T. D.; Haag, A.; Auchtung, J. M.
10.1101/2024.07.17.603937 — microbiology — Posted on 2024-07-17
2397 A Metagenomic Approach Does Not Elucidate Uremic Toxin Levels in Hemodialysis Patients.
Taft, D.; Quinones, J. M.; Moreno, M. L.; Fatani, A.; Suh, J.; Gorwitz, G.; Wang, Y.; Segal, M. S.; Dahl, W. J.
10.1101/2024.07.16.603811 — microbiology — Posted on 2024-07-17
2399 Seed banking alters native seed microbiome composition and function relative to natural populations
Russell, D. H.; Rajabal, V.; Alfonzetti, M.; Van der Merwe, M. M.; Gallagher, R.; Tetu, S. G.
10.1101/2024.07.16.603074 — microbiology — Posted on 2024-07-17
2401 The catheterized bladder environment induces dysregulation of macrophage polarization exacerbating bacterial UTI
Marrufo, A. M.; Molina, J. J.; Gager, C.; Andersen, M. J.; La Bella, A. A.; Lucas, E.; Wongso, E.; Urmi, T.; Arias-Parbul, K.; Webster, R.; Stuckey, P. V.; Kohler, K. N.; Donahue, D.; Ploplis, V.; Flick, M. J.; Castellino, F. J.; Santiago-Tirado, F. H.; Flores-Mireles, A. L.
10.1101/2024.07.16.603761 — immunology — Posted on 2024-07-17
2402 F-CPI: Prediction of activity changes induced by fluorine substitution using multimodal deep learning
Zhang, Q.; Yin, W.; Chen, X.; Zhou, A.; Zhang, G.; Zhao, Z.; Li, Z.; Zhang, Y.; Shen, J.; Zhu, W.; Jiang, X.; Xu, Z.
10.1101/2024.07.17.602844 — bioinformatics — Posted on 2024-07-17
2404 Rapid neurostimulation at micron scale with optically controlled thermal-capture technique
Romshin, A. M.; Aseyev, N.; Idzhilova, O. S.; Koryagina, A. A.; Zeeb, V. E.; Vlasov, I. I.; Balaban, P. M.
10.1101/2024.07.15.603492 — biophysics — Posted on 2024-07-17
2407 HCS-3DX, a next-generation AI-driven automated 3D high-content screening system
Diosdi, A.; Toth, T.; Grexa, I.; Schrettner, B.; Hapek, N.; Kovacs, F.; Kriston, A.; Harmati, M.; Buzas, K.; Pampaloni, F.; Piccinini, F.; Horvath, P.
10.1101/2024.07.15.603536 — bioinformatics — Posted on 2024-07-17
2409 COLLAGE: COnsensus aLignment of muLtiplexing imAGEs
Antoranz, A.; Arnould, A.; Andhari, M. D.; Nazari, P.; Shankar, G.; De Moor, B.; De Smet, F.; Bosisio, F. M.; Pey, J.
10.1101/2024.07.15.603557 — bioinformatics — Posted on 2024-07-17
2414 Beyond A and B Compartments: how major nuclear locales define nuclear genome organization and function
Gholamalamdari, O.; van Schaik, T.; Wang, Y.; Kumar, P.; Zhang, L.; Zhang, Y.; Gonzalez, G. A. H.; Vouzas, A. E.; Zhao, P. A.; Gilbert, D. M.; Ma, J.; van Steensel, B.; Belmont, A. S.
10.1101/2024.04.23.590809 — genomics — Posted on 2024-07-17
2415 Stratifying variant deleteriousness and trait-modulating effect under human recent adaptation
Fan, X.; Huang, D.; Dong, X.; Yi, X.; Wang, J.; Zhang, S.; Dong, X.; Gu, X.; Li, M.; Sham, P. C.; Zhou, W.; Li, M. J.
10.1101/2024.07.15.603534 — genetics — Posted on 2024-07-17
2420 Heritable intraspecific variation among prey in size and movement interact to shape predation risk and potential natural selection
Coblentz, K. E.; Yang, L.; Dalal, A.; Incarnato, M. M. N.; Thilakarathne, D. D.; Shaw, C.; Wilson, R.; Biagioli, F.; Montooth, K. L.; DeLong, J. P.
10.1101/2024.01.11.575285 — ecology — Posted on 2024-07-17
2421 Fine-Scale Models of Bee Species Diversity and Habitat in New York State
Buckner, M. A.; White, E. L.; Howard, T. G.; Schlesinger, M. D.; Danforth, B. N.
10.1101/2024.07.15.603570 — ecology — Posted on 2024-07-17
2422 Characterization of Multicellular Niches Supporting Hematopoietic Stem Cells Within Distinct Zones
Dong, R.; Li, H.; He, X. C.; Wang, C.; Perera, A.; Malloy, S.; Russell, J.; Li, W.; Petentler, K.; Mao, X.; Yang, Z.; Epp, M.; Hall, K.; Scott, A.; McKinney, M. C.; Huang, S.; Smith, S.; Hembree, M.; Wang, Y.; Yu, Z.; Haug, J.; Unruh, J.; Slaughter, B.; Kang, X.; Li, L.
10.1101/2024.06.28.601225 — developmental biology — Posted on 2024-07-17
2423 UGGT1-mediated reglucosylation of N-glycan competes with ER-associated degradation of unstable and misfolded glycoproteins
Ninagawa, S.; Matsuo, M.; Ying, D.; Oshita, S.; Aso, S.; Matsushita, K.; Taniguchi, M.; Fueki, A.; Yamashiro, M.; Sugasawa, K.; Saito, S.; Imami, K.; Kizuka, Y.; Sakuma, T.; Yamamoto, T.; Yagi, H.; Kato, K.; Mori, K.
10.1101/2023.10.18.562958 — cell biology — Posted on 2024-07-17
2424 CHC22 clathrin functions in the early secretory pathway by two-site interaction with SNX5 and p115
Greig, J.; Bates, G. T.; Yin, D. I.; Briant, K.; Simonetti, B.; Cullen, P. J.; Brodsky, F. M.
10.1101/2022.12.21.520923 — cell biology — Posted on 2024-07-17
2427 HINT1 Inhibitors as Selective Modulators of MOR-NMDAR Cross Regulation and Non-Opioid Analgesia
Dillenburg, M.; Peterson, C. D.; Dolat, R.; Ligori, K.; Kitto, K. F.; Wilcox, G. L.; Fairbanks, C. A.; Wagner, C. R.
10.1101/2024.07.15.603568 — neuroscience — Posted on 2024-07-17
2428 LSD Modulates Proteins Involved in Cell Proteostasis, Energy Metabolism and Neuroplasticity in Human Brain Organoids
Costa, M. d. N.; Goto-Silva, L.; Nascimento, J. M.; Domith, I.; Karmirian, K.; Feilding, A.; Trindade, P.; Martins-de-Souza, D.; Rehen, S. K.
10.1101/2024.01.30.577659 — neuroscience — Posted on 2024-07-17
2430 Mistargeted retinal axons form synaptically segregated subcircuits in the visual thalamus of albino mice
McCracken, S.; McCoy, L.; Hu, Z.; Hodges, J. A.; Valkova, K.; R. Williams, P.; Morgan, J.
10.1101/2024.07.15.603571 — neuroscience — Posted on 2024-07-17
2435 Convolvulaceae of Guinea: taxonomy, conservation and useful plants
Davis, B.; Couch, C.; Bidault, E.; Simbiano, F. J.; Molmou, D.; Felipe Almeida, R.; Simoes, A. R. G.
10.1101/2024.07.15.602708 — plant biology — Posted on 2024-07-17
2440 Modeling causal signal propagation in multi-omic factor space with COSMOS
Dugourd, A.; Lafrenz, P.; Mananes, D.; Fallegger, R.; Kroger, A.-C.; Turei, D.; Shtylla, B.; Saez-Rodriguez, J.
10.1101/2024.07.15.603538 — bioinformatics — Posted on 2024-07-17
2445 Parallelized Droplet Vitrification Enables Single-Run Vitrification of the Whole Rat Liver Hepatocyte Yield
Taggart, M. S.; Tchir, A.; Van Dieren, L.; Chen, H.; Hassan, M.; Taveras, C.; Lellouch, A. G.; Toner, M.; Sandlin, R. D.; Uygun, K.
10.1101/2024.07.14.603471 — bioengineering — Posted on 2024-07-17
2446 A Mathematical Exploration of SDH-b Loss in Chromaffin Cells
Vera-Siguenza, E.; Rana, H.; Nashiebi, R.; Cloete, I.; Kluckova, K.; Spill, F.; Tennant, D. A.
10.1101/2024.07.15.603520 — bioengineering — Posted on 2024-07-17
2451 Growth of soil ammonia-oxidizing archaea on air-exposed solid surface.
Abiola, C.; Gwak, J.-H.; Lee, U.-J.; Awala, S. I.; Jung, M.-Y.; Park, W.; Rhee, S.-K.
10.1101/2024.07.15.603479 — ecology — Posted on 2024-07-17
2452 Effects of maize development and phenology on the field infestation dynamics of the European Corn Borer
Revillon, S.; Dillmann, C.; Galic, N.; Bauland, C.; Palaffre, C.; Malvar, R. A.; Butron, A.; Rebaudo, F.; Legrand, J.
10.1101/2024.01.29.577014 — ecology — Posted on 2024-07-17
2453 Using nature-based citizen science initiatives to enhance nature connection and mental health.
Oh, R. R. Y.; Suarez-castro, A.; Fuller, R.; Tervo, M.; Rozario, K.; Peters, B.; Chowdhury, S.; von Goenner, J.; Friedrichs-Manthey, M.; Berger, A.; Schultz, T.; Dean, A.; Tulloch, A.; Bonn, A.
10.1101/2024.07.14.603425 — ecology — Posted on 2024-07-17
2454 Generation and application of novel hES cell reporter lines for the differentiation and maturation of hPS cell-derived islet-like clusters
Zanfrini, E.; Bandral, M.; Jarc, L.; Ramirez-Torres, A. M.; Kufrin, V.; Rodriguez-Aznar, E.; Cohrs, C.; Speier, S.; Neumann, K.; Gavalas, A.
10.1101/2024.07.15.603551 — developmental biology — Posted on 2024-07-17
2457 Changes in the Public IgM Repertoire and its Idiotypic Connectivity in Alzheimer's Disease and Frontotemporal Dementia
Pashova-Dimov, S.; Petrov, P.; Karachanak-Yankova, S.; Belezhanska, D.; Zhelev, Y.; Mehrabian, S.; Traykov, L.; Pashov, A.
10.1101/2024.07.15.603559 — immunology — Posted on 2024-07-17
2459 Loss of MEF2C function by enhancer mutation leads to neuronal mitochondria dysfunction and motor deficits in mice
Yousefian-Jazi, A.; Kim, S.; Choi, S.-H.; Chu, J.; Nguyen, P. T.-T.; Park, U.; Lim, K.; Hwang, H.; Lee, K.; Kim, Y.; Hyeon, S. J.; Rhim, H.; Ryu, H. L.; Lim, G.; Stein, T. D.; Ryu, H.; Lee, J.
10.1101/2024.07.15.603186 — neuroscience — Posted on 2024-07-17
2461 Neurophysiological correlates of cortical hierarchy across the lifespan
Fehring, J.; Balestrieri, E.; Focke, N.; Dannlowski, U.; Stier, C.; Gross, J.
10.1101/2024.07.15.602693 — neuroscience — Posted on 2024-07-17
2463 Criticality explains structure-function relationships in the human brain
Angiolelli, M.; Scarpetta, S.; Sorrentino, P.; Troisi Lopez, E.; Quarantelli, M.; Granata, C.; Sorrentino, G.; Palmieri, V.; Messuti, G.; Stefano, M.; Filippi, S.; Cherubini, C.; Loppini, A.; Chiodo, L.
10.1101/2024.07.15.603226 — neuroscience — Posted on 2024-07-17
2468 A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective and anti-inflammatory properties following status epilepticus in mice
Ferhat, L.; Soussi, R.; Masse, M.; Kyriatzis, G.; Girard, S.; Gassiot, F.; Gaudin, N.; Laurencin, M.; Bernard, A.; Bole, A.; Ferracci, G.; Smirnova, M.; Roman, F.; Dive, V.; Cisternino, S.; Temsamani, J.; David, M.; Lecorche, P.; Jacquot, G.; KHRESTCHATISKY, M.
10.1101/2024.07.15.603208 — neuroscience — Posted on 2024-07-17
2471 Oxytocin facilitates social behavior of female rats via selective modulation of interneurons in the medial prefrontal cortex
Schimmer, S.; Lefevre, A.; Lebedeva, J.; Rozov, A.; Kania, A.; Raftogianni, A.; Afordakos, K.; Tiwari, R.; Netser, S.; Patwell, R.; Hefter, D.; Boender, A.; Podpecan, Y.; Schubert, T.; Sanetra, A.; Trenk, A.; Gugula, A.; Hurlemann, R.; Althammer, F.; Blasiak, A.; Melzer, S.; Monyer, H.; Wagner, S.; Eliava, M.; Grinevich, V.
10.1101/2024.07.15.603543 — neuroscience — Posted on 2024-07-17
2474 Human gut microbiota interactions shape the long-term growth dynamics and evolutionary adaptations of Clostridioides difficile
Sulaiman, J. E.; Thompson, J.; Cheung, P. L. K.; Qian, Y.; Mill, J.; James, I.; Vivas, E.; Simcox, J.; Venturelli, O. S.
10.1101/2024.07.15.603560 — systems biology — Posted on 2024-07-17
2477 A novel repressor-activator-competitor module comprising C2H2 zinc finger and NAC transcription factors regulates rice grain development
Jaiswal, P.; Priyadarshini, R.; Yadav, A.; V, A. P.; Mahto, A.; Mathew, I.; Das, U.; Qasim, F.; Vichitra, A.; Panwar, A.; Verma, A.; Tyagi, A. K.; Agarwal, P.
10.1101/2024.07.15.603577 — plant biology — Posted on 2024-07-17
2479 Cx43 Enhances Response to BRAF/MEK Inhibitors by Reducing DNA Repair Capacity
Varela-Vazquez, A.; Guitian-Caamano, A.; Carpintero-Fernandez, P.; Alvarez, V.; Carneiro-Figueira, A.; Varela-Eirin, M.; Calleja-Chucla, T.; Bravo, S.; Vidal, A.; Sendon-Lago, J.; Rodriguez-Candela Mateos, M.; Caeiro, J. R.; Blanco, M. G.; Sabio, G.; Rivas, C.; Santamaria, D.; Fernandez-Lozano, C.; Fonseca, E.; Huertas, P.; Sanchez-Laorden, B.; Alabert, C.; Mayan, M. D.
10.1101/2024.07.15.601645 — cancer biology — Posted on 2024-07-17
2482 Mechanism of host cell invasion by Leishmania through KMP-11 mediated cholesterol-transport and membrane phase transition
Chattopadhyay, K.; Sannigrahi, A.; Ghosh, S.; pradhan, s.; JANA, P.; Jawed, J. J.; Majumdar, S.; ROY, S.; KARMAKAR, S.; Mukherjee, B.
10.1101/2024.07.15.603533 — biophysics — Posted on 2024-07-17
2483 Mixtures of Intrinsically Disordered Neuronal Protein Tau and Anionic Liposomes Reveal Distinct Anionic Liposome-Tau Complexes Coexisting with Tau Liquid-Liquid Phase Separated Coacervates
Tchounwou, C.; Jobanputra, A. J.; Lasher, D.; Fletcher, B. J.; Jacinto, J.; Bhaduri, A.; Best, R. L.; Fisher, W. S.; Ewert, K. K.; Li, Y.; Feinstein, S. C.; Safinya, C. R.
10.1101/2024.07.15.603342 — biophysics — Posted on 2024-07-17
2485 Towards a Taxonomy Machine. A Training Set of 5.6 Million Arthropod Images
Steinke, D.; Ratnasingham, S.; Agda, J.; Ait Boutou, H.; Box, I.; Boyle, M.; Chan, D.; Feng, C.; Lowe, S. C.; McKeown, J. T.; McLeod, J.; Sanchez, A.; Smith, I.; Walker, S.; Wei, C. Y.-Y.; Hebert, P. D. N.
10.1101/2024.07.15.600863 — bioinformatics — Posted on 2024-07-17
2486 BMAP: a comprehensive and reproducible biomedical data analysis platform
Ren, Y.; Cheng, Z.; Li, L.; Zhang, Y.; Dai, F.; Deng, L.; Wu, Y.; Gu, J.; Lin, Q.; Wang, X.; Kong, Y.; Lu, H.
10.1101/2024.07.15.603507 — bioinformatics — Posted on 2024-07-17
2492 Placental-brain axis in females detected within broadly impacted metabolic gene networks protects against prenatal PCB exposure
Chau, K.; Neier, K.; Valenzuela, A. E.; Schmidt, R. J.; Durbin-Johnson, B. P.; Lein, P. J.; Korf, I.; LaSalle, J.
10.1101/2024.07.14.603326 — genomics — Posted on 2024-07-17
2498 FGF Signaling Regulates Development of the Anterior Fontanelle
Bobzin, L.; Nickle, A.; Ko, S.; Ince, M.; Bhojwani, A.; Merrill, A. E.
10.1101/2024.07.14.603452 — developmental biology — Posted on 2024-07-17
2500 HERV-derived epitopes represent new targets for T-cell based immunotherapies in ovarian cancer
Bonaventura, P.; Tabone, O.; Estornes, Y.; Page, A.; Mutez, V.; Delles, M.; Moran, S.; Dubois, C.; Lacourrege, M.; Tawfik, D.; Etchegaray, E.; Valente, A.; Boulos, R.; Jimenez Dominguez, G.; Chuvin, N.; Gadot, N.; Wang, Q.; Valladeau-Guilemond, J.; Depil, S.
10.1101/2024.07.13.603392 — immunology — Posted on 2024-07-17
2501 CyNET- a network analysis framework for high dimensionality, system level analyses of the functional Immunome
Kumar, P.; Yeo, J. G.; Poh, S. L.; Nur Hazirah, S.; Sutamam, N. B.; ang, G. W.; Chellamuthu, V. R.; Wasser, M.; Leong, J. Y.; Ramakrishna, L.; Arkachaisri, T.; Albani, S.
10.1101/2024.07.15.603495 — immunology — Posted on 2024-07-17
2508 Induction of long-term hyperexcitability by memory-related cAMP signaling in isolated nociceptor cell bodies
Bavencoffe, A.; Zhu, M. Y.; Neerukonda, S. V.; Johnson, K. N.; Dessauer, C. W.; Walters, E. T.
10.1101/2024.07.13.603393 — neuroscience — Posted on 2024-07-17
2509 The barley MLA13-AVRA13 heterodimer reveals principles for immunoreceptor recognition of RNase-like powdery mildew effectors
Lawson, A. W.; Flores-Ibarra, A.; Cao, Y.; An, C.; Neumann, U.; Gunkel, M.; Saur, I. M. L.; Chai, J.; Behrmann, E.; Schulze-Lefert, P.
10.1101/2024.07.14.603419 — plant biology — Posted on 2024-07-17
2512 Moderate-term dimethyl fumarate treatment reduces pathology of dystrophic skeletal and cardiac muscle in a mouse model
Kourakis, S.; Timpani, C. A.; Bagaric, R. M.; Qi, B.; Ali, B. A.; Boyer, R.; Spiesberger, G.; Kandhari, N.; Peterson, A. L.; Debrincat, D.; Yates, T. J.; Yan, X.; Stupka, N.; Kuang, J.; Nijagal, B.; Deveson-Lucas, D.; Fischer, D.; Rybalka, E.
10.1101/2024.07.13.601627 — pathology — Posted on 2024-07-17
2513 Oncogene inactivation-induced senescence facilitates tumor relapse
Schmitt, P.; Hoenig, K.; Milojkovic, A.; Anders, K.; Schroeck, E.; Sauer, S.; Uyar, B.; Akalin, A.; Martinez-Reyes, I.; Blankenstein, T.
10.1101/2024.07.13.603369 — cancer biology — Posted on 2024-07-17
2514 Targeting fatty acid synthase suppresses tumor development in NF2/CDKN2A-deficient malignant pleural mesothelioma
Karnan, S.; OTA, A.; Hasan, M. N.; Murakami, H.; Rahman, M. L.; Wahiduzzaman, M.; Shihan, M. T. A. S. T. A.; Jahan, N.; Vu, L. Q.; Hanamura, I.; Inoko, A.; Riku, M.; Ito, H.; Kaneko, Y.; Lin, Y.; Hyodo, T.; Konishi, H.; Tsuzuki, S.; Hosokawa, Y. H.
10.1101/2024.07.14.603191 — cancer biology — Posted on 2024-07-17
2516 Reversible disulfide bond crosslinks as tunable levers of phase separation in designer biomolecular condensates.
Mondal, M.; Jankoski, P. E.; Lee, L. D.; Dinakarapandian, D. M.; Chiu, T.-Y.; Swetman, W. S.; Wu, H.; Paravastu, A. K.; Clemons, T. D.; Rangachari, V.
10.1101/2024.07.13.603402 — biophysics — Posted on 2024-07-17
2520 Towards Reliable Diabetes Prediction: Innovations in Data Engineering and Machine Learning Applications
Talukder, M. A.; Islam, M. M.; Uddin, M. A.; Kazi, M.; Khalid, M.; Akhter, A.; Moni, M. A.
10.1101/2024.07.14.603436 — bioinformatics — Posted on 2024-07-17
2522 Chromosome-level genome assembly and annotation of Corallium rubrum: a Mediterranean coral threatened by overharvesting and climate change.
Ledoux, J.-B.; Gomez-Garrido, J.; Cruz, F.; Camara, F.; Matos, A.; Sarropoulou, X.; Ramirez-Calero, S.; Aurelle, D.; Lopez-Sendino, P.; Grayson, N.; Moore, B.; Antunes, A.; Aguilera, L.; Gut, M.; Salces-Ortiz, J.; Fernandez, R.; Linares, C.; Garrabou, J.; Alioto, T.
10.1101/2024.07.13.603384 — genomics — Posted on 2024-07-17
2524 eDNA metabarcoding shows highly diverse but distinct shallow, mid-water, and deep-water eukaryotic communities within a marine biodiversity hotspot
Cerrillo-Espinosa, P.; Calderon-Aguilera, L. E.; Medina-Rosas, P.; Gomez-Gutierrez, J.; Reyes-Bonilla, H.; Cupul-Magana, A.; Gonzalez-Cuellar, O. T.; Munguia-Vega, A.
10.1101/2024.07.14.603441 — genomics — Posted on 2024-07-17
2527 Dynamical forces drive organ morphology changes during embryonic development
Manna, R. K.; Retzlaff, E. M.; Hinman, A. M.; Lan, Y.; Abdel-Razek, O.; Bates, M.; Hehnly, H.; Amack, J. D.; Manning, M. L.
10.1101/2024.07.13.603371 — developmental biology — Posted on 2024-07-17
2529 ACID: A Comprehensive Toolbox for Image Processing and Modeling of Brain, Spinal Cord, and Post-mortem Diffusion MRI Data
David, G.; Fricke, B.; Oeschger, J. M.; Ruthotto, L.; Fritz, F. J.; Ohana, O.; Mordhorst, L.; Sauvigny, T.; Freund, P.; Tabelow, K.; Mohammadi, S.
10.1101/2023.10.13.562027 — neuroscience — Posted on 2024-07-17
2534 B cell receptor silencing reveals the origin of high-grade B cell lymphomas with MYC and BCL2 rearrangements
Sindaco, P.; Lonardi, S.; Varano, G.; Pietrini, I.; Morello, G.; Balzarini, P.; Neuman, H.; Vit, F.; Bertolazzi, G.; Arima, H.; Chiarini, M.; Lorenzi, L.; Pellegrini, V.; Giampaolo, S.; Garzon, D.; Ranise, C.; Bugatti, M.; Pagani, C.; Daffini, R.; Mainoldi, F.; Selvarasa, V.; Sivacegaram, A.; Yang, H.; Ying, L.; Cancila, V.; Bonnal, R.; Visco, E.; Gonzalez, C. L.; Capaccio, P.; Ferreri, A. J. M.; Tucci, A.; Cabras, A. D.; Pruneri, G.; di Napoli, A.; Siebert, R.; Bomben, R.; Falini, B.; Pizzi, M.; Song, J. Y.; Chan, W. C.; Ponzoni, M.; Mehr, R.; Tripodo, C.; Facchetti, F.; Casola, S.
10.1101/2024.07.13.603066 — cancer biology — Posted on 2024-07-17
2535 Marker Data Enhancement For Markerless Motion Capture
Falisse, A.; Uhlrich, S.; Chaudhari, A.; Hicks, J.; Delp, S.
10.1101/2024.07.13.603382 — bioengineering — Posted on 2024-07-17
2536 Targeting CD19 for the treatment of autoimmune with a novel T cell engager
Yuan, A. Q.; Zhao, L.; Bai, L.; Wang, Y.; Yang, I.; Yuan, R. Q.; Meng, Q.; Dai, X.
10.1101/2024.02.17.580750 — immunology — Posted on 2024-07-17
2538 Transcriptomic analysis of the human habenula in schizophrenia
Yalcinbas, E. A.; Ajanaku, B.; Nelson, E. D.; Garcia-Flores, R.; Eagles, N. J.; Montgomery, K. D.; Stolz, J. M.; Wu, J.; Divecha, H. R.; Chandra, A.; Bharadwaj, R.; Bach, S.; Rajpurohit, A.; Tao, R.; Pertea, G.; Shin, J.-H.; Kleinman, J. E.; Hyde, T. M.; Weinberger, D. R.; Huuki-Myers, L. A.; Collado-Torres, L.; Maynard, K. R.
10.1101/2024.02.26.582081 — neuroscience — Posted on 2024-07-17
2540 PhotoFiTT: A Quantitative Framework for Assessing Phototoxicity in Live-Cell Microscopy Experiments
Del Rosario, M.; Gomez-de-Mariscal, E.; Morgado, L.; Portela, R.; Jacquemet, G.; Pereira, P. M.; Henriques, R.
10.1101/2024.07.16.603046 — cell biology — Posted on 2024-07-17
2541 Toxicological evaluation of Vanillin Flavor in E-Liquid Aerosols on Endothelial Cell Function: Findings from the Replica Project
Emma, R.; Sun, A.; Partsinevelos, K.; Rust, S.; Volarevic, V.; Lesmana, R.; Giordano, A.; Goenawan, H.; Barliana, M. I.; Arsenijevic, A.; Kastratovic, N.; Markovic, V.; Spasic, B.; Distefano, A.; Orlando, L.; Carota, G.; Polosa, R.; Caruso, M.; Li Volti, G.
10.1101/2024.01.20.576442 — pharmacology and toxicology — Posted on 2024-07-17
2544 Proxi-RIMS-seq2 applied to native microbiomes uncovers hundreds of known and novel m5C methyltransferase specificities.
Yang, W.; Luyten, Y.; Reister, E.; Mangelson, H.; Sisson, Z.; Auch, B.; Liachko, I.; Roberts, R. J.; Ettwiller, L.
10.1101/2024.07.15.603628 — genomics — Posted on 2024-07-17
2545 Evolution of phenotypic plasticity during environmental fluctuations
Sekajova, Z.; Fossen, E. I. F.; Rosa, E.; Ratikainen, I. I.; Tourniaire-Blum, M.; Bolund, E.; Lind, M. I.
10.1101/2023.01.22.523389 — evolutionary biology — Posted on 2024-07-17
2546 TNFR2 loss leads to decreased TOX expression in T cells without affecting TIM3 and improves responses to tumor and chronic LCMV
Hoyt-Miggelbrink, A.; Waibl Polania, J.; Wachsmuth, L.; Lorrey, S. J.; Mohan, A.; Hardigan, A. A.; Blandford, E.; Lerner, E.; Wilkinson, D.; Hotchkiss, K.; Cook, S.; Hemmers, S.; Patel, A.; Ayasoufi, K.; Fecci, P. E.
10.1101/2024.07.12.603311 — immunology — Posted on 2024-07-17
2547 Using an ODE model to separate Rest and Task signals in fMRI
Kashyap, A.; Geenjaar, E. P. T.; Bey, P.; Dhindsa, J.; Glomb, K.; Plis, S.; Keilholz, S.; Ritter, P.
10.1101/2023.10.23.563564 — neuroscience — Posted on 2024-07-17
2554 Human FASTK preferentially binds single-stranded and G-rich RNA
Dawidziak, D. M.; Dzadz, D. A.; Kuska, M. I.; Kanavalli, M.; Klimecka, M. M.; Merski, M.; Bandyra, K. J.; Gorna, M. W.
10.1101/2024.07.16.603671 — molecular biology — Posted on 2024-07-17
2556 Dietary Branched Chain Amino Acids Modify Post-Infarct Cardiac Remodeling and Function in the Murine Heart
Nguyen, D. C.; Wells, C. K.; Taylor, M. S.; Martinez-Ondaro, Y. R.; Brittian, K. R.; Brainard, R. E.; Moore, J. B.; Hill, B. G.
10.1101/2024.07.12.603348 — physiology — Posted on 2024-07-17
2558 CompareM2 is a genomes-to-report pipeline for comparing microbial genomes
Kobel, C. M.; Aho, V. T. E.; Oyas, O.; Norskov-Lauritsen, N.; Woodcroft, B. J.; Pope, P. B.
10.1101/2024.07.12.603264 — bioinformatics — Posted on 2024-07-17
2559 Toward industrial C8 production: Oxygen intrusion drives renewable n caprylate production from ethanol and acetate via intermediate metabolite production
Gemeinhardt, K.; Seung Jeon, B.; Nepomuscene Ntihuga, J.; Wang, H.; Schlaiss, C.; Lucas, T. N.; Bessarab, I.; Nalpas, N. C.; Zhou, N.; Usack, J. G.; Huson, D.; Williams, R.; Macek, B.; Aristilde, L.; Angenent, L. T.
10.1101/2024.07.12.603245 — bioengineering — Posted on 2024-07-17
2561 Reproductive modes in populations of late-acting self-incompatible and self-compatible polyploid Ludwigia grandiflora subsp. hexapetala in western Europe
stoeckel, S.; Becheler, R.; Portillo-Lemus, L.; Harang, M.; Besnard, A.-L.; Lassalle, G.; Causse-Vedrines, R.; Michon-Coudouel, S.; Park, D. J.; Pope, B.; Petit, E. J.; BARLOY, D. H.
10.1101/2024.03.21.586104 — evolutionary biology — Posted on 2024-07-17
2564 High fat diet induces differential age- and gender-dependent changes in neuronal function linked to redox stress.
de Lange, M.; Yarosh, V.; Farel, K.; Oates, C.; Patil, R.; Hawthorn, I.; Jung, M.-M.; Wenje, S.; Steinert, J. R.
10.1101/2024.07.12.603123 — neuroscience — Posted on 2024-07-17
2567 Dynamic PRC1-CBX8 stabilizes a porous structure of chromatin condensates
Uckelmann, M.; Levina, V.; Taveneau, C.; Ng, X. H.; Pandey, V.; Martinez, J.; Mendiratta, S.; Houx, J.; Boudes, M.; Venugopal, H.; Trepout, S.; Zhang, Q.; Flanigan, S.; Li, M.; Sierecki, E.; Gambin, Y.; Das, P. P.; Bell, O.; de Marco, A.; Davidovich, C.
10.1101/2023.05.08.539931 — biophysics — Posted on 2024-07-17
2568 An emerging view of neural geometry in motor cortex supports high-performance decoding
Perkins, S. M.; Amematsro, E. A.; Cunningham, J. P.; Wang, Q.; Churchland, M. M.
10.1101/2023.04.05.535396 — bioengineering — Posted on 2024-07-17
2569 Inherited CDA-I disease: anemia-associated mutations disrupt CDIN1-Codanin1 complex
Stojaspal, M.; Brom, T.; Janovic, T.; Necasova, I.; Veverka, P.; Uhrik, L.; Hernychova, L.; Hofr, C.
10.1101/2023.05.25.542057 — biochemistry — Posted on 2024-07-17
2571 Actin dynamics sustains spatial gradients of membrane tension in adherent cells
Garcia-Arcos, J. M.; Mehidi, A.; Sanchez Velazquez, J.; Guillamat, P.; Tomba, C.; Houzet, L.; Capolupo, L.; D'Angelo, G.; Colom, A.; Hinde, E.; Aumeier, C.; Roux, A.
10.1101/2024.07.15.603517 — cell biology — Posted on 2024-07-17
2574 Protein complex heterogeneity and topology revealed by electron capture charge reduction and surface induced dissociation
Shaw, J. B.; Harvey, S. R.; Du, C.; Xu, Z.; Edgington, R. M.; Olmedillas, E.; Saphire, E. O.; Wysocki, V. H.
10.1101/2024.03.07.583498 — biophysics — Posted on 2024-07-17
2576 PhotoFiTT: A Quantitative Framework for Assessing Phototoxicity in Live-Cell Microscopy Experiments
Del Rosario, M.; Gomez-de-Mariscal, E.; Morgado, L.; Portela, R.; Jacquemet, G.; Pereira, P. M.; Henriques, R.
10.1101/2024.07.16.603046 — cell biology — Posted on 2024-07-16
2578 Sub-nucleolar trafficking of Hendra virus matrix protein is regulated by ubiquitination and oligomerisation
Rawlinson, S. M.; Zhao, T.; Gomez, F. A.; David, C. T.; Rootes, C. L.; Veuglers, P. F.; Rozario, A. M.; Stewart, C. R.; Bell, T. D. M.; Moseley, G. W.
10.1101/2023.08.10.552741 — microbiology — Posted on 2024-07-17
2581 On the synergy between myelin proteins P0, MBP, and P2 in peripheral nerve major dense line formation
Krokengen, O. C.; Raasakka, A.; Klenow, M. B.; Pal, A.; Hetland, O.; Mularski, A.; Ruskamo, S.; Pedersen, J. S.; Simonsen, A. C.; Kursula, P.
10.1101/2024.07.15.603506 — biochemistry — Posted on 2024-07-16
2584 Proteomic analysis identifies dysregulated proteins in albuminuria: a South African pilot study
Khoza, S.; George, J. A.; Naicker, P.; Stoychev, S. H.; Fabian, J.; Govender, I. S.
10.1101/2024.07.16.603438 — biochemistry — Posted on 2024-07-16
2585 Stabilised D2R G-protein coupled receptor oligomers identify multi-state β-arrestin complexes
Sharrocks, K. L.; Fanelli, F.; Milner, A. J.; Lui, Y.; Yining, W.; Byrne, B.; Hanyaloglu, A.
10.1101/2024.07.16.603735 — cell biology — Posted on 2024-07-16
2586 Polymer physics models reveal structural folding features of single-molecule gene chromatin conformations
Conte, M.; Abraham, A.; Esposito, A.; Yang, L.; Gibcus, J. H.; Parsi, K. M.; Vercellone, F.; Fontana, A.; Di Pierno, F.; Dekker, J.; Nicodemi, M.
10.1101/2024.07.16.603769 — molecular biology — Posted on 2024-07-16
2589 P-BODY AND CYTOSKELETON REMODELING BY ORTHOHANTAVIRUSES.
Schwarzer-Sperber, H. S.; Petrich, A.; Schade, M.; Nilson, N.; Chibrac-Ahad, L.; Lehmann, M. J.; Paulick, K.; Weiss, S.; Bourquain, D.; Witkowski, P. T.; Krüger, D. H.; Herrmann, A.; Schwarzer, R.
10.1101/2024.07.16.603662 — microbiology — Posted on 2024-07-16
2591 The stress-protectant molecule trehalose mediates fluconazole tolerance in Candida glabrata
Zhu, Q.; Wijnants, S.; Feil, R.; Vergauwen, R.; Lunn, J. E.; Van Ende, M.; Van Dijck, P.
10.1101/2024.07.16.603661 — microbiology — Posted on 2024-07-16
2594 An essential role for the Hv1 voltage-gated proton channel in Pseudomonas aeruginosa corneal infection
Rodriguez, P.; Abbondante, S.; Marshall, M. M.; Abdelmeseh, J.; Tombola, F.; Pearlman, E.
10.1101/2024.07.15.603631 — microbiology — Posted on 2024-07-16
2596 Chlamydia muridarum Causes Persistent Subclinical Infection and Elicits Innate and Adaptive Immune Responses in C57BL/6J, BALB/cJ and J:ARC(S) Mice Following Exposure to Shedding Mice
Mishkin, N.; Carrasco, S. E.; Palillo, M. B.; Momtsios, P.; Woods, C.; Henderson, K. S.; Longhini, A. L. F.; Otis, C.; Gardner, R.; Joseph, A. M.; Sonnenberg, G. F.; Palillo, J.; Ricart Arbona, R. J.; Lipman, N. S.
10.1101/2024.07.16.603732 — microbiology — Posted on 2024-07-16
2597 Peptide-enabled ribonucleoprotein delivery for CRISPR engineering (PERC) in primary human immune cells and hematopoietic stem cells
Sahu, S.; Castro, M.; Muldoon, J. J.; Asija, K.; Wyman, S. K.; Krishnappa, N.; Eyquem, J.; Nguyen, D. N.; Wilson, R. C.
10.1101/2024.07.14.603391 — bioengineering — Posted on 2024-07-16
2598 Allosteric regulation of the tyrosine phosphatase PTP1B by a protein-protein interaction
Chartier, C. A.; Woods, V. A.; Xu, Y.; van Vlimmeren, A. E.; Jovanovic, M.; McDermott, A. E.; Keedy, D. A.; Shah, N. H.
10.1101/2024.07.16.603632 — biochemistry — Posted on 2024-07-16
2599 SlNAP2 promoted fruit ripening by directly binding the ACS2 promoter and interacting with EIL3
Wu, X.; Fang, H.; Huang, D.; Hou, X.; Qiao, Y.; Li, C.; Li, A.; Huang, Y.; Zhang, Z.; Liu, Z.; Liu, Y.; Liao, W.
10.1101/2024.07.15.603576 — biochemistry — Posted on 2024-07-16
2600 Molecular basis of FIGNL1 in dissociating RAD51 from DNA and chromatin
Carver, A.; Yu, T.-Y.; Yates, L.; White, T.; Wang, R.; Lister, K.; Jasin, M.; Zhang, X.
10.1101/2024.07.16.603765 — biochemistry — Posted on 2024-07-16
2601 Diffusing protein binders to intrinsically disordered proteins
Liu, C.; Wu, K.; Choi, H.; Han, H.; Zhang, X.; Watson, J. L.; Shijo, S.; Bera, A. K.; Kang, A.; Brackenbrough, E.; Coventry, B.; Hick, D. R.; Hoofnagle, A. N.; Zhu, P.; Li, X.; Decarreau, J.; Gerben, S. R.; Yang, W.; Wang, X.; Lamp, M.; Murray, A.; Bauer, M.; Baker, D.
10.1101/2024.07.16.603789 — biochemistry — Posted on 2024-07-16
2602 Titration-WB: A methodology for accurate quantitative protein determination overcoming reproducibility errors
Maestri, A.; Ehrenborg, E.; Werngren, O.; Olin, M.; Hagberg, C. E.; Pedrelli, M.; Parini, P.
10.1101/2024.07.16.603677 — biochemistry — Posted on 2024-07-16
2604 Cryo-EM Structures of Saccharolobus solfataricus Initiation Complexes with Leaderless mRNAs Highlight Archaeal Features and Eukaryotic Proximity
BOURGEOIS, G.; Coureux, P.-D.; lazennec-Schurdevin, c.; MADRU, C.; Gaillard, T.; Duchateau, M.; Chamot-Rooke, J.; Bourcier, S.; Mechulam, Y.; Schmitt, E.
10.1101/2024.07.16.603699 — molecular biology — Posted on 2024-07-16
2605 Spatial evidence of cryptic methane cycling and methylotrophic metabolisms along a land-ocean transect in a California coastal wetland
Krause, S. J. E.; Wipfler, R. L.; Liu, J.; Yousavich, D. J.; Robinson, D.; Hoyt, D. W.; Orphan, V. J.; Treude, T.
10.1101/2024.07.16.603764 — microbiology — Posted on 2024-07-16
2609 Identification of V. parvula and S. gordonii adhesins mediating co-aggregation and its impact on physiology and mixed biofilm structure
DORISON, L.; BECHON, N.; MARTIN-GALLAUSIAUX, C.; CHAMORRO RODRIGUEZ, S. V.; VITRENKO, Y.; OUAZAHROU, R.; VILLA, R.; DESCHAMPS, J.; BRIANDET, R.; GRIBALDO, S.; GHIGO, J.-M.; BELOIN, C.
10.1101/2024.07.16.603716 — microbiology — Posted on 2024-07-16
2612 Dissecting human monoclonal antibody responses from mRNA- and protein-based XBB.1.5 COVID-19 monovalent vaccines
Fantin, R.; Clark, J.; Cohn, H.; Jaiswal, D.; Bozarth, B.; Civljak, A.; Rao, V.; Lobo, I.; Nardulli, J.; Srivastava, K.; Yong, J.; Andreata-Santos, R.; Bushfield, K.; Lee, E.; Singh, G.; Study group, P.; Kleinstein, S.; Krammer, F.; Simon, V.; Bajic, G.; Coelho, C.
10.1101/2024.07.15.602781 — immunology — Posted on 2024-07-16
2614 The SARS-CoV-2 nucleocapsid protein inhibits the cellular Nonsense-Mediated mRNA Decay (NMD) pathway preventing the full enzymatic activation of UPF1.
Nuccetelli, V.; Mghezzi-Habellah, M.; Deymier, S.; Roisin, A.; Gerard-Baraggia, F.; Rocchi, C.; Coureux, P.-D.; Gouet, P.; Cimarelli, A.; Mocquet, V.; Fiorini, F.
10.1101/2024.07.16.603692 — biochemistry — Posted on 2024-07-16
2615 Caenorhabditis elegans SynMuv B gene activity is down-regulated during a viral infection to enhance RNA interference
Seetharaman, A.; Galagali, H.; Linarte, E.; Liu, M. H. X.; Cohen, J. D.; Chetal, K.; Sadreyev, R.; Tate, A. J.; Montgomery, T. A.; Ruvkun, G.
10.1101/2024.07.12.603258 — genetics — Posted on 2024-07-16
2616 Lineage-specific genomic imprinting in the ZNF791 locus
Ahn, J.; Hwang, I.-S.; Park, M.-R.; Rosa-Velazquez, M.; Cho, I.-C.; Relling, A. E.; Hwang, S.; Lee, K.
10.1101/2024.07.13.603355 — genetics — Posted on 2024-07-16
2619 High fat diet induces differential age- and gender-dependent changes in neuronal function linked to redox stress.
de Lange, M.; Yarosh, V.; Farel, K.; Oates, C.; Patil, R.; Hawthorn, I.; Jung, M.-M.; Wenje, S.; Steinert, J. R.
10.1101/2024.07.12.603123 — neuroscience — Posted on 2024-07-16
2620 ROLE OF FORELIMB MORPHOLOGY IN MUSCLE SENSORIMOTOR FUNCTIONS DURING LOCOMOTION IN THE CAT
Rahmati, S. M.; Klishko, A. N.; Martin, R. S.; Bunderson, N. E.; Meslie, J. A.; Nichols, T. R.; Rybak, I. A.; Frigon, A.; Burkholder, T. J.; Prilutsky, B. I.
10.1101/2024.07.11.603106 — neuroscience — Posted on 2024-07-16
2622 The Calmodulin-like proteins, CML13 and CML14 Function as Myosin Light Chains for the Class XI Myosins in Arabidopsis
Symonds, K.; Duff, L.; Dwivedi, V.; Belausov, E.; Pal, L.; Tominaga, M.; Haraguchi, T.; Sadot, E.; Ito, K.; Snedden, W.
10.1101/2024.07.11.603113 — plant biology — Posted on 2024-07-16
2624 Portal bile acids and microbiota along the murine intestinal tract exhibit sex differences in physiology
Reichardt, F.; Lucas, L.; Okyere, L.; Choi, J.; Amador-Nogez, D.; Gaulke, C.; Anakk, S.
10.1101/2024.07.12.603325 — physiology — Posted on 2024-07-16
2627 Cells in the Polyaneuploid Cancer Cell State are Pro-Metastatic
Mallin, M. M.; Rolle, L. T. A.; Schmidt, M. J.; Priyadarsini Nair, S.; Zurita, A. J.; Kuhn, P.; Hicks, J.; Pienta, K. J.; Amend, S. R.
10.1101/2024.07.12.603285 — cancer biology — Posted on 2024-07-16
2629 Localized in vivo gene editing of murine cancer-associated fibroblasts
Kuhn, N. F.; Zaleta-Linares, I.; Nyberg, W. A.; Eyquem, J.; Krummel, M. F.
10.1101/2024.07.11.603114 — bioengineering — Posted on 2024-07-16
2630 Highly quantitative measurement of differential protein-genome binding with PerCell chromatin sequencing
Tallan, A.; Kucinski, J.; Sunkel, B.; Taslim, C.; LaHaye, S.; Liu, Q.; Qi, J.; Wang, M.; Kendall, G. C.; Stanton, B. Z.
10.1101/2024.07.12.603283 — genomics — Posted on 2024-07-16
2632 Two liverworts from same habitats developed many similar but few distinct seasonal adaptive strategies: Insights from a transcriptomic approach
Basu, S.; Yadav, S.; Jha, V. K.; Biswas, S.; Srivastava, A.; Tripathi, K.; Mondal, R.; Chaurasia, N.; Singh, S. K.; Mishra, Y.
10.1101/2024.07.12.603233 — genomics — Posted on 2024-07-16
2633 MalKinID: A Likelihood-Based Model for Identifying Malaria Parasite Genealogical Relationships Using Identity-by-Descent
Wong, W.; Wang, L.; Schaffner, S.; Li, X.; Cheeseman, I. H.; Anderson, T. J.; Vaughan, A. M.; Ferdig, M. T.; Volkman, S. K.; Hartl, D. L.; Wirth, D.
10.1101/2024.07.12.603328 — genetics — Posted on 2024-07-16
2635 Long-term population dynamics of an endangered butterfly are influenced by hurricane-mediated disturbance
Steele Cabrera, S.; Belitz, M.; Emmel, T.; Khazan, E.; Standridge, M.; Rossetti, K.; Daniels, J.
10.1101/2024.07.12.603220 — ecology — Posted on 2024-07-16
2637 Single-cell transcriptomics reveal differences between chorionic and basal plate cytotrophoblasts and trophoblast stem cells
Morey, R. E.; Soncin, F.; Kallol, S.; Sah, N.; Manalo, Z.; Bui, T.; Slamecka, J.; Cheung, V. C.; Pizzo, D.; Requena, D. F.; Chang, C.-W.; Farah, O.; Kittle, R.; Meads, M.; Horii, M.; Fisch, K.; Parast, M. M.
10.1101/2024.07.12.603155 — developmental biology — Posted on 2024-07-16
2639 An enterococcal phage protein broadly inhibits type IV restriction enzymes involved in antiphage defense
Bullen, N. P.; Johnson, C. N.; Andersen, S. E.; Arya, G.; Marotta, S. R.; Lee, Y.-J.; Weigele, P.; Whitney, J. C.; Duerkop, B. A.
10.1101/2023.11.16.567456 — microbiology — Posted on 2024-07-16
2640 IFNγ initiates TLR9-dependent autoimmune hepatitis in DNase II deficient mice
Hao, K.; Gao, K. M.; Strauss, M.; Subramanian, S.; Marshak-Rothstein, A.
10.1101/2024.07.10.602775 — immunology — Posted on 2024-07-16
2641 A SMARTR workflow for multi-ensemble atlas mapping and brain-wide network analysis
Jin, M.; Ogundare, S.; Lanio, M.; Sorid, S.; Whye, A. R.; Leal Santos, S.; Franceschini, A.; Denny, C. A.
10.1101/2024.07.12.603299 — neuroscience — Posted on 2024-07-16
2643 Fc-engineered large molecules targeting blood-brain barrier transferrin receptor and CD98hc have distinct central nervous system and peripheral biodistribution compared to standard antibodies
Khoury, N.; Pizzo, M. E.; Discenza, C. B.; Joy, D.; Tatarakis, D.; Todorov, M. I.; Negwer, M.; Ha, C.; De Melo, G. L.; Sarrafha, L.; Simon, M. J.; Chan, D.; Chau, R.; Chew, K.; Chow, J.; Clemens, A.; Robles-Colmenares, Y.; Dugas, J. C.; Duque, J.; Kaltenecker, D.; Kane, H.; Leung, A.; Lozano, E.; Moshkforoush, A.; Roche, E.; Sandmann, T.; Tong, M.; Xa, K.; Zhou, Y.; Lewcock, J. W.; Erturk, A.; Thorne, R. G.; Calvert, M. E. K.; Zuchero, Y. J. Y.
10.1101/2024.07.11.602993 — neuroscience — Posted on 2024-07-16
2645 Cerebellar output shapes cortical preparatory activity during motor adaptation
Israely, S.; Ninou, H.; Rajchert, O.; Elmaleh, L.; Harel, R.; Mawase, F.; Kadmon, J.; Prut, Y.
10.1101/2024.07.12.603354 — neuroscience — Posted on 2024-07-16
2647 Residual Microglia Following Short-term PLX5622 Treatment in 5xFAD Mice Exhibit Diminished NLRP3 Inflammasome and mTOR Signaling, and Enhanced Autophagy
Kodali, M.; Madhu, L. N.; Somayaji, Y.; Attaluri, S.; Huard, C.; Panda, P. K.; Shankar, G.; Rao, S.; Shuai, B.; Gonzalez, J. J.; Oake, C.; Hering, C.; Babu, R. S.; Kotian, S.; Shetty, A. K.
10.1101/2024.07.11.603157 — neuroscience — Posted on 2024-07-16
2648 Functional analysis of conserved C. elegans bHLH family members uncovers lifespan control by a peptidergic hub neuron
Aguilar, G. R.; Vidal, B.; Ji, H.; Evenblij, J.; Ji, H.; Valperga, G.; Liao, C.-P.; Fang-Yen, C.; Hobert, O.
10.1101/2024.07.12.603289 — neuroscience — Posted on 2024-07-16
2649 Female sex hormones exacerbate retinal neurodegeneration
Rowe, A. A.; Reyes, S.; Velasquez, M. J.; Yee, T.; Nettesheim, E. R.; McDonald, J. G.; Wert, K. J.
10.1101/2024.07.11.603104 — neuroscience — Posted on 2024-07-16
2652 ExPOSE: A comprehensive toolkit to perform expansion microscopy in plant protoplast systems
Cox, K. L.; Pardi, S. A.; O'Connor, L.; Klebanovych, A.; Huss, D. J.; Nusinow, D. A.; Meyers, B. C.; Czymmek, K. J.
10.1101/2024.07.12.603300 — plant biology — Posted on 2024-07-16
2654 FLASH Bragg-peak irradiation with a therapeutic carbon ion beam: first in vivo results
Tinganelli, W.; Sokol, O.; Puspitasari, A.; Helm, A.; Simoniello, P.; Schuy, C.; Lerchl, S.; Eckert, D.; Oppermann, J.; Rehm, A.; Janssen, S.; Engel, D.; Moeller, R.; Romano, R.; Fournier, C.; Durante, M.; Weber, U.
10.1101/2024.07.12.603197 — cancer biology — Posted on 2024-07-16
2655 Mapping the genetic landscape establishing a tumor immune microenvironment favorable for anti-PD-1 response in mice and humans
Skelly, D. A.; Graham, J. P.; Cheng, M.; Furuta, M.; Walter, A.; Stoklasek, T. A.; Yang, H.; Stearns, T. M.; Poirion, O.; Zhang, J.-G.; Grassmann, J. D. S.; Luo, D.; Flynn, W. F.; Courtois, E. T.; Chang, C.-H.; Serreze, D. V.; Menghi, F.; Reinholdt, L. G.; Liu, E. T.
10.1101/2024.07.11.603136 — cancer biology — Posted on 2024-07-16
2656 Drug-repurposing screen identifies thiostrepton as a novel regulator of the tumor suppressor DAB2IP
De Florian Fania, R.; Maiocchi, S.; Klima, R.; Pellegrini, V.; Ghetti, S.; Selvestrel, D.; Fava, L. L.; Braga, L.; Collavin, L.
10.1101/2024.07.12.603185 — cancer biology — Posted on 2024-07-16
2657 Rhabdomyosarcoma fusion oncoprotein initially pioneers a neural signature in vivo
Kucinski, J.; Tallan, A.; Taslim, C.; Wang, M.; Cannon, M. V.; Silvius, K. M.; Stanton, B. Z.; Kendall, G. C.
10.1101/2024.07.12.603270 — cancer biology — Posted on 2024-07-16
2658 Context-dependent roles for autophagy in myeloid cells in tumor progression
Choi, J.; Park, G.; Lee, S. S.-Y.; Dominici, E.; Becker, L.; Macleod, K. F.; KRON, S. J.; Hwang, S.
10.1101/2024.07.12.603292 — cancer biology — Posted on 2024-07-16
2662 The discovery of phages in the Substantia Nigra and its implication for Parkinson's Disease
Zhao, Y.; Xiong, C.; Wang, B.; Li, D.; Liu, J.; Wei, S.; Hou, Y.; Zhou, Y.; Zheng, R.
10.1101/2024.07.13.603353 — bioinformatics — Posted on 2024-07-16
2666 CompareM2 is a genomes-to-report pipeline for comparing microbial genomes
Kobel, C. M.; Aho, V. T. E.; Oeyaas, O.; Noerskov-Lauritsen, N.; Woodcroft, B. J.; Pope, P. B.
10.1101/2024.07.12.603264 — bioinformatics — Posted on 2024-07-16
2669 16,000 combinatorial DNA rings">Assembling a true "Olympic Gel" from >16,000 combinatorial DNA rings
Speed, S.; Atabay, A.; Peng, Y.-H.; Gupta, K.; Müller, T.; Fischer, C.; Sommer, J.-U.; Lang, M.; Krieg, E.
10.1101/2024.07.12.603212 — bioengineering — Posted on 2024-07-16
2671 Specialization into Host Sea Anemones Impacted Clownfish Demographic Responses to Pleistocene Sea Level Changes
Garcia Jimenez, A.; Gaboriau, T.; Fitzgerald, L. M.; Heim, S.; Marcionetti, A.; Schmid, S.; Bertrand, J.; Litsios, G.; Frederich, B.; Cortesi, F.; Yemin, T.; Salamin, N.
10.1101/2024.07.12.603135 — genomics — Posted on 2024-07-16
2672 Distinct structural and functional heterochromatin partitioning of lamin B1 and B2 revealed using genome-wide Nicking Enzyme Epitope targeted DNA sequencing.
Sen, S.; Esteve, P. O.; Karthikeyan, R.; Beaulieu, J.; Chin, H. G.; Feehary, G.; Vishnu, U. S.; Xu, S. y.; Samuelson, J.; Pradhan, S.
10.1101/2024.07.11.603107 — genomics — Posted on 2024-07-16
2673 Somy evolution in the honey bee infecting trypanosomatid parasite, Lotmaria passim
Markowitz, L. M.; Nearman, A.; Zhao, Z.; Boncristiani, D.; Butenko, A.; de Pablos, L. M.; Marin, A.; Xu, G.; Machado, C. A.; Schwarz, R. S.; Palmer-Young, E. C.; Evans, J. D.
10.1101/2024.07.12.603340 — genomics — Posted on 2024-07-16
2675 Waves of transcription drive erythroid differentiation and launch the NRF2-activated antioxidant program
Karppi, I.; Pessa, J. C.; Rabenius, A.; Himanen, S.; Prajapati, B.; Barkman Jonsson, E.; Vartiainen, M. K.; Sistonen, L.; Vihervaara, A.
10.1101/2024.07.12.603281 — genomics — Posted on 2024-07-16
2677 Consistent and scalable monitoring of birds and habitats along a coffee production intensity gradient
Somveille, M.; Grainger-Hull, J.; Ferguson, N.; Sethi, S. S.; Gonzalez Garcia, F.; Chassagnon, V.; Oktem, C.; Disney, M.; Lopez Bautista, G.; Vandermeer, J.; Perfecto, I.
10.1101/2024.07.12.603271 — ecology — Posted on 2024-07-16
2679 Modeling plant-microbe interactions with species distribution models
Wang, Z.; Piche-Choquette, S.; Lauzon, J.; Ishak, S.; Kembel, S. W.
10.1101/2024.07.12.603317 — ecology — Posted on 2024-07-16
2680 Unbounding fish: Assessing vulnerability to overexploitation for transboundary fish populations
Gangal, M.; Arthur, R.; Suri, V.; Pandit, A.; Tyagi, A.; Prakash, P.; Sule, M.; Majgaonkar, I.; Krishnaswamy, J.; Ramakrishnan, U.
10.1101/2024.07.12.603026 — ecology — Posted on 2024-07-16
2682 The Once and Future Fish: 1300 years of Atlantic herring population structure and demography revealed through ancient DNA and mixed-stock analysis
Atmore, L. M.; van der Jagt, I.; Boilard, A.; Haeberle, S.; Blevis, R.; Dierickx, K.; Quinlan, L. M.; Orton, D. C.; Hufthammer, A. K.; Barrett, J. H.; Star, B.
10.1101/2024.07.11.603078 — ecology — Posted on 2024-07-16
2683 Pulsatile dynamics propagate crystalline order in the developing Drosophila eye
Couturier, L.; Luna-Escalante, J.; Mazouni, K.; Mestdagh, C.; Phan, M.-S.; Tinevez, J.-Y.; Schweisguth, F.; Corson, F.
10.1101/2024.07.11.603179 — developmental biology — Posted on 2024-07-16
2684 Dysregulation of gene expression during gastrulation results in impaired primitive erythropoiesis and vascular development in Trim71-KO embryos
Beckroege, T.; Jux, B.; Seifert, H.; Theobald, H.; De Domenico, E.; Paulusch, S.; Beyer, M.; Schlitzer, A.; Mass, E.; Kolanus, W.
10.1101/2024.07.12.603214 — developmental biology — Posted on 2024-07-16
2685 A Single Trophoblast Layer Acts as the Gatekeeper at the Endothelial-Hematopoietic Crossroad in the Placenta
Home, P.; Ghosh, A.; Kumar, R. P.; Ray, S.; Gunewardena, S.; Kumar, R.; Dasgupta, P.; Roy, N.; Saha, A.; Ouseph, M. M.; Leone, G. W.; Paul, S.
10.1101/2024.07.12.603303 — developmental biology — Posted on 2024-07-16
2690 Card9 and MyD88 differentially regulate Th17 immunity to the commensal yeast Malassezia in the murine skin
Tuor, M.; Stappers, M. H. T.; Ruchti, F.; Desgardin, A.; Sparber, F.; Orr, S. J.; Gow, N. A. R.; LeibundGut-Landmann, S.
10.1101/2024.07.12.603211 — immunology — Posted on 2024-07-16
2691 Langerhans cells regulate immunity in adulthood by regulating postnatal dermal lymphatic development
Sim, J. H.; Bell, R.; Feng, Z.; Chyou, S.; Shipman, W.; Kataru, R.; Ivashkiv, L.; Mehrara, B.; Lu, T.
10.1101/2024.07.12.603312 — immunology — Posted on 2024-07-16
2692 YTHDF2 upregulation and relocation dictate CD8 T cell polyfunctionality in tumor immunity
Zhang, H.; Luo, X.; Yang, W.; Wu, Z.; Zhao, Z.; Pei, X.; Zhang, X.; Chen, C.; Lei, J. H.; Shi, Q.; Zhao, Q.; Chen, Y.; Wu, W.; Zeng, Z.; Ju, H.-Q.; Qiu, M.; Liu, J.; Shen, B.; Chen, M.; Chen, J.; Deng, C.-X.; Xu, R.-H.; Hou, J.
10.1101/2024.07.11.603088 — immunology — Posted on 2024-07-16
2693 Macrophage-derived CCL24 promotes fibrosis and worsens cardiac dysfunction during heart failure
Parthiban, P.; Barrow, F.; Nguyen, H.; Neto, F.; Florczak, K.; Wang, H.; Yucel, D.; Liu, H.; Draxler, M.; Ciske, E.; Fredrickson, G.; Herman, A.; Rothenberg, M.; Dudley, S.; van Berlo, J. H.; Revelo, X.
10.1101/2024.07.12.603277 — immunology — Posted on 2024-07-16
2699 Direct piriform-to-auditory cortical projections shape auditory-olfactory integration
Vogler, N. W.; Chen, R.; Virkler, A.; Tu, V. Y.; Gottfried, J. A.; Geffen, M. N.
10.1101/2024.07.11.602976 — neuroscience — Posted on 2024-07-16
2700 Mild neonatal hypoxia disrupts adult hippocampal learning and memory and is associated with CK2-mediated dysregulation of synaptic calcium-activated potassium channel KCNN2
Riddle, A.; Srivastava, T.; Wang, K.; Tellez, E.; O'neill, H.; Gong, X.; O'Neil, A.; Bell, J. A.; Raber, J.; Lattal, M.; Maylie, J.; Back, S. A.
10.1101/2024.07.10.602558 — neuroscience — Posted on 2024-07-16
2707 7 Tesla MRS estimates of GABA concentration relate to physiological measures of tonic inhibition in the human motor cortex
Paparella, I.; Cardone, P.; Zanichelli, B.; Lamalle, L.; Collette, F.; Sherif, S.; Zubkov, M.; Clarke, W. T.; Stagg, C. J.; Maquet, P.; Vandewalle, G.
10.1101/2024.07.12.603209 — neuroscience — Posted on 2024-07-16
2708 Persistent activity during working memory maintenance predicts long-term memory formation in the human hippocampus
Daume, J.; Kaminski, J.; Salimpour, Y.; Anderson, W. S.; Valiante, T. A.; Mamelak, A. N.; Rutishauser, U.
10.1101/2024.07.15.603630 — neuroscience — Posted on 2024-07-16
2711 Tracking changes in functionality and morphology of repopulated microglia in young and old mice
Kaminska, B.; Luczak-Sobotkowska, Z.; Rosa, P.; Banqueri-Lopez, M.; Ochocka, N.; Kiryk, A.; Lenkiewicz, A. M.; Fuhrmann, M.; Jankowski, A.
10.1101/2024.07.12.603244 — neuroscience — Posted on 2024-07-16
2712 REM sleep quality is associated with balanced tonic activity of the locus coeruleus during wakefulness
Mortazavi, N.; Talwar, P.; Koshmanova, E.; Sharifpour, R.; Beckers, E.; Berger, A.; Campbell, I.; Paparella, I.; Balda, F.; Dardour Hamzaoui, I.; Berthomier, C.; Bastin, C.; Phillips, C.; Maquet, P.; Collette, F.; Zubkov, M.; Lamalle, L.; Vandewalle, G.
10.1101/2024.07.12.603275 — neuroscience — Posted on 2024-07-16
2713 Cell-type specific binocular interactions in mouse visual thalamus
Masterson, S. P.; Govindaiah, G. E.; Guido, W.; Bickford, M. E.
10.1101/2024.07.12.603141 — neuroscience — Posted on 2024-07-16
2715 Generation of human appetite-regulating neurons and tanycytes from stem cells
Abay-Norgaard, Z.; Mueller, A. K.; Hanninen, E.; Rausch, D.; Piilgaard, L.; Christensen, J. B.; Peeters, S.; Schorling, A. L.; Salvador, A.; Nikulina, V.; Li, Y. K.; Kajtez, J.; Pers, T. H.; Kirkeby, A.
10.1101/2024.07.11.603039 — neuroscience — Posted on 2024-07-16
2717 Spatial Transcriptomics and Single-Nucleus Multi-omics Analysis Revealing the Impact of High Maternal Folic Acid Supplementation on Offspring Brain Development
Xie, H.; Xu, X.; Lin, Y.; Yin, L.; Serpa, P. d. S.; Conacher, B.; Pacholac, C.; Carvallo, F.; Hrubec, T.; Farris, S.; Zimmerman, K.; Wang, X.
10.1101/2024.07.12.603269 — neuroscience — Posted on 2024-07-16
2718 Systematic evaluation of blastoid models of early human development
Kim, H. J.; Salehin, N.; Huang, H.; Zhang, X.; Jothi, R.; Yang, P.
10.1101/2024.07.11.603073 — systems biology — Posted on 2024-07-16
2720 Climate adaptation in P. trichocarpa: key adaptive loci identified for stomata and leaf traits
Klein, M. C.; Meng, Z.; Bailey-Bale, J.; Milner, S.; Shi, P.; Muchero, W.; Chen, J.-G.; Tschaplinski, T. J.; Jacobson, D.; Lagergren, J.; Lane, M.; O Brien, C.; Chhetri, H.; Shu, M.; Freer-Smith, P.; Buckley, T. N.; Magney, T.; Monroe, J. G.; Tuskan, G. A.; Taylor, G.
10.1101/2024.07.11.603099 — plant biology — Posted on 2024-07-16
2721 Species wide inventory of Arabidopsis thaliana organellar variation reveals ample phenotypic variation for photosynthetic performance
Theeuwen, T. P. J. M.; Wijfjes, R. Y.; Dorussen, D.; Lawson, A. W.; Lind, J.; Jin, K.; Boekeloo, J.; Tijink, D.; Hall, D.; Hanhart, C.; Becker, F. F. M.; van Eeuwijk, F. A.; Kramer, D. M.; Wijnker, E.; Harbinson, J.; Koornneef, M.; Aarts, M. G. M.
10.1101/2024.07.12.603232 — plant biology — Posted on 2024-07-16
2722 DGTS overproduced in seed plants is excluded from plastid membranes and promotes endomembrane expansion
Salomon, S.; Schilling, M.; Albrieux, C.; Si Larbi, G.; Jouneau, P.-H.; Roy, S.; Falconet, D.; Michaud, M.; Jouhet, J.
10.1101/2024.07.11.603045 — plant biology — Posted on 2024-07-16
2723 Effects of leg immobilization and recovery resistance training on skeletal muscle-molecular markers in previously resistance trained versus untrained adults
Michel, J. M.; Godwin, J. S.; Plotkin, D. L.; McIntosh, M. C.; Mattingly, M. L.; Agostinelli, P. J.; Mueller, B. J.; Anglin, D. A.; Berry, A. C.; Vega, M. M.; Pipkin, A. A.; Stock, M. S.; Graham, Z. A.; Baweja, H. S.; Mobley, C. B.; Bamman, M. M.; Roberts, M. D.
10.1101/2024.07.12.603321 — physiology — Posted on 2024-07-16
2725 Importance of transcript variants in transcriptome analyses
Vo, K.; Mohamadi, R.; Sharma, Y.; Mohamadi, A.; Fields, P. E.; Rumi, M. A. K.
10.1101/2024.07.11.603122 — bioinformatics — Posted on 2024-07-16
2728 Improving rigor and reproducibility in chromatin immunoprecipitation assay data analysis workflows with Rocketchip
Haghani, V.; Goyal, A.; Zhang, A.; Sharifi, O.; Mariano, N.; Yasui, D. H.; Korf, I. F.; LaSalle, J. M.
10.1101/2024.07.10.602975 — bioinformatics — Posted on 2024-07-16
2729 Peptipedia v2.0: A peptide sequence database and user-friendly web platform. A major update
Cabas, G. E.; Daza, A.; Soto, N.; Garrido, V.; Alvarez, D.; Navarrete, M.; Sarmiento-Varon, L.; Sepulveda, J.; D. Davari, M. E.; Cadet, F.; Olivera, A.; Uribe, R.; Medina-Ortiz, D.
10.1101/2024.07.11.603053 — bioinformatics — Posted on 2024-07-16
2733 BOOST: a robust ten-fold expansion method on hour-scale
Guo, J.; Yang, H.; Lu, C.; Cui, D.; Zhao, M.; Li, C.; Chen, W.; Yang, Q.; Li, Z.; Chen, M.; Zhao, S.; Zhou, J.; He, J.; Jiang, H.
10.1101/2024.07.11.603043 — bioengineering — Posted on 2024-07-16
2735 Toward industrial C8 production: Oxygen intrusion drives renewable n caprylate production from ethanol and acetate via intermediate metabolite production
Gemeinhardt, K.; Seung Jeon, B.; Nepomuscene Ntihuga, J.; Wang, H.; Schlaiss, C.; Niklas, T. N.; Bessarab, I.; Nalpas, N. C.; Zhou, N.; Usack, J. G.; Huson, D.; Williams, R.; Macek, B.; Aristilde, L.; Angenent, L. T.
10.1101/2024.07.12.603245 — bioengineering — Posted on 2024-07-16
2736 Fructose-2,6-bisphosphate restores DNA repair activity of PNKP and ameliorates neurodegenerative symptoms in Huntingtons disease
CHAKRABORTY, A.; Sreenivasmurthy, S. G.; Miller, W.; Huai, W.; Biswas, T.; Mandal, S. M.; Bosca, L.; Krishnan, B.; Ghosh, G.; Hazra, T.
10.1101/2023.10.26.564220 — biochemistry — Posted on 2024-07-16
2737 Comparative evaluation of four exome enrichment solutions in 2024: Agilent, Roche, Vazyme and Nanodigmbio
Belova, V.; Vasiliadis, I.; Repinskaia, Z.; Samitova, A.; Shmitko, A.; Ponikarovskaya, N.; Suchalko, O.; Cheranev, V.; Shatalov, P.; Shegai, P.; Kaprin, A.; Rebrikov, D.; Korostin, D.
10.1101/2024.07.11.602872 — genomics — Posted on 2024-07-16
2741 Robust coexistence in ecological competitive communities
Lechon-Alonso, P.; Kundu, S.; Lemos-Costa, P.; Allesina, S.
10.1101/2024.07.10.602979 — ecology — Posted on 2024-07-16
2745 First-male sperm precedence in polyandrous Spodoptera frugiperda allows sterile males induce population suppression
Sun, H.; Bu, L.-A.; Zhang, X.-Y.; Zhang, Z.-R.; Zhu, L.-Y.; Su, S.; Guo, D.; Hu, G.; Gao, C.-F.; Palli, S. R.; Champer, J.; Wu, S.-F.
10.1101/2024.07.10.602994 — zoology — Posted on 2024-07-16
2746 Appearance of green tea compounds in plasma following green tea consumption is modulated by the gut microbiome in mice
Sterrett, J. D.; Quinn, K. D.; Doenges, K. A.; Nusbacher, N.; Levens, C. L.; Armstrong, M. L.; Reisdorph, R. M.; Smith, H.; Saba, L. M.; Kuhn, K. A.; Lozupone, C.; Reisdorph, N.
10.1101/2024.07.11.603097 — systems biology — Posted on 2024-07-16
2751 Platelet integrin αIIbβ3 plays a key role in venous thrombogenesis in a mouse model
Adair, B. D.; Field, C. O.; Alonso, J. L.; Xiong, J.-P.; Deng, S.-X.; Ahn, H. S.; Mashin, E.; Clish, C. B.; van Agthoven, J.; Yeager, M.; Guo, Y.; Tess, D. A.; Landry, D. W.; Poncz, M.; Arnaout, M. A.
10.1101/2024.07.11.602533 — pathology — Posted on 2024-07-16
2752 Effects of clinically relevant radionuclides on the activation of a type I interferon response by radiopharmaceuticals in syngeneic murine tumor models
Kerr, C. P.; Sheehan-Klenk, J.; Grudzinski, J. J.; Adam, D. P.; Nguyen, T. P. T.; de Aguiar Ferreira, C.; Bates, A. M.; Jin, W. J.; Kwon, O.; Olson, A. P.; Lin, W.; Hyun, M.; Jagodinsky, J. C.; Powers, M.; Sriramaneni, R. N.; Clark, P. A.; Shea, A. G.; Comas Rojas, H.; Choi, C.; Massey, C. F.; Zangl, L. M.; Pinchuk, A. N.; Aluicio-Sarduy, E.; Kim, K.; Engle, J. W.; Hernandez, R.; Bednarz, B. P.; Weichert, J. P.; Morris, Z. S.
10.1101/2024.07.10.602990 — cancer biology — Posted on 2024-07-16
2756 Identification of Southeast Asian Anopheles mosquito species with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry using a cross-correlation approach
Chaumeau, V.; Sawasdichai, S.; Min, T. Z. M. M. M.; Kulabkeeree, T.; Jaruwan, N.; Gloria, N.; Yu Lee, N.; Trackoolchengkaew, M.; Phanaphadungtham, M.; Rongthong, P.; Inta, A.; Watthanaworawit, W.; Nosten, F.
10.1101/2024.07.10.602996 — bioinformatics — Posted on 2024-07-16
2759 Influence of salinity on the thermal tolerance of aquatic organisms
Farias, L.; Beszteri, B.; Castellanos, A.; Doliwa, A.; Enss, J.; Feld, C.; Grabner, D.; Lampert, K.; Mayombo, S.; Prati, S.; Schuerings, C.; Smollich, E.; Schaefer, R.; Sures, B.; Le, Y. T. T.
10.1101/2024.07.11.603038 — ecology — Posted on 2024-07-16
2762 Hemogenic endothelium of the vitelline and umbilical arteries is the major contributor to mouse fetal lympho-myelopoiesis
Barone, C.; Quattrini, G.; Orsenigo, R.; Timoteo-Ferreira, F.; Muratore, A.; Cazzola, A.; Patelli, A.; Soares-da-Silva, F.; Nicholls, M.; Mauri, M.; Bombelli, S.; De Marco, S.; D'Aliberti, D.; Spinelli, S.; Bonalume, V.; Domingues, A.; Sala, G.; Colonna, A.; D'Errico, E.; D'Orlando, C.; Bianchi, C.; Perego, R. A.; Meneveri, R.; de Bruijn, M.; Cumano, A.; Fantin, A.; Brunelli, S.; Piazza, R.; Azzoni, E.
10.1101/2024.07.11.603050 — developmental biology — Posted on 2024-07-16
2763 Fundamental parameters governing the transmission of conjugative plasmids
Rodriguez-Grande, J.; Ortiz, Y.; Garcillan-Barcia, M. d. P.; de la Cruz, F.; Fernandez, R.
10.1101/2023.07.11.548640 — microbiology — Posted on 2024-07-16
2764 Determining potential immunomodulatory drug efficacy in sepsis using ELISpot
Walton, A. H.; Mazer, M. B.; Remy, K. E.; Davitt, E. B.; Griffith, T. S.; Gould, R. W.; Badovinac, V. P.; Brakenridge, S. C.; Drewry, A. M.; Loftus, T. J.; Efron, P. A.; Moldawer, L. L.; Caldwell, C. C.; Hotchkiss, R. S.
10.1101/2024.07.10.602970 — immunology — Posted on 2024-07-16
2765 Gut-specific H3R signaling orchestrates microglia-dependent resolution of peripheral inflammation
Duerholz, K.; Linnerbauer, M.; Schmid, E.; Danzer, H.; Loesslein, L.; Amend, L.; Ehnes, L.; Frech, M.; Azizov, V.; Schaelter, F.; Gessner, A.; Lucas, S.; Lesker, T.-R.; Taudte, R. V.; Hofmann, J.; Beyer, F.; Bootz-Maoz, H.; Reich, Y.; Romano, H.; Mauro, D.; Beckervordersandvorth, R.; Xiang, W.; Haghikia, A.; Akdis, C. A.; Ciccia, F.; Baeuerle, T.; Sarter, K.; Strowig, T.; Yissachar, N.; Schett, G.; Rothhammer, V.; Zaiss, M. M.
10.1101/2024.07.11.603031 — immunology — Posted on 2024-07-16
2766 MAGE-A4-Responsive Plasma Cells Promote Non-Small Cell Lung Cancer
Armstrong, D.; Chang, C.-Y.; Hong, M. J.; Green, L. K.; Hudson, W.; Shen, Y.; Song, L.-Z.; Jammi, S.; Casal, B.; Creighton, C. J.; Carisey, A.; Zhang, X.; McKenna, N.; Kang, S.; Lee, H.-S.; Corry, D.; Kheradmand, F.
10.1101/2024.07.10.602985 — immunology — Posted on 2024-07-16
2768 H105A peptide eye drops promote photoreceptor survival in murine and human models of retinal degeneration
Bernardo-Colon, A.; Bighinati, A.; Parween, S.; Debnath, S.; Piano, I.; Adani, E.; Corsi, F.; Gargini, C.; Vergara, N.; Marigo, V.; Becerra, S. P.
10.1101/2024.07.10.602890 — neuroscience — Posted on 2024-07-16
2769 Sequential Transitions of Male Sexual Behaviours Driven by Dual Acetylcholine-Dopamine Dynamics
Miyasaka, A.; Kanda, T.; Nonaka, N.; Terakoshi, Y.; Cherasse, Y.; Ishikawa, Y.; Li, Y.; Takizawa, H.; Seita, J.; Yanagisawa, M.; Sakurai, T.; Sakurai, K.; Liu, Q.
10.1101/2023.12.21.572798 — neuroscience — Posted on 2024-07-16
2771 APP beta-CTF triggers cell-autonomous synaptic toxicity independent of Abeta
Luo, M.; Zhou, J.; Sun, C.; Chen, W.; Fu, C.; Si, C.; Zhang, Y.; Geng, Y.; Chen, Y.
10.1101/2024.07.11.603028 — neuroscience — Posted on 2024-07-16
2772 WITHDRAWN: Immune regulators EDS1 and PAD4 constrain ADR1-dependent disease resistance in rice
Fernandes, J.; Wang, J.; Su, R.; Lee, T.; Zheng, Z.; Perin, S.; Cesari, S.; Jalilian, A.; Sciallano, C.; Szurek, B.; Cui, H.; Kroj, T.; Parker, J. E.
10.1101/2024.04.08.588512 — plant biology — Posted on 2024-07-16
2774 CLEC18A interacts with sulfated GAGs and controls clear cell renal cell carcinoma progression
Jonsson, G.; Hofmann, M.; Mereiter, S.; Hartley-Tassell, L.; Sakic, I.; Oliveira, T.; Hoffmann, D.; Novatchkova, M.; Schleiffer, A.; Penninger, J. M.
10.1101/2024.07.08.602586 — cancer biology — Posted on 2024-07-16
2785 Plant-to-plant reactive oxygen signal transmission via a Cuscuta bridge
Fichman, Y.; Pelaez-Vico, M. A.; Mudalige, A.; Lee, H.; Mittler, R.; Park, S.
10.1101/2023.07.13.548730 — plant biology — Posted on 2024-07-16
2787 Quantifying "just-right" APC inactivation for colorectal cancer initiation
Brunet Guasch, M.; Feeley, N.; Soriano, I.; Thorn, S.; Tomlinson, I.; Nicholson, M.; Antal, T.
10.1101/2024.07.10.602868 — cancer biology — Posted on 2024-07-16
2789 Emergence of cellular nematic order is a conserved feature of gastrulation in animal embryos
Li, X.; Huebner, R. J.; Williams, M. L. K.; Sawyer, J.; Peifer, M.; Wallingford, J. B.; Thirumalai, D.
10.1101/2024.07.11.603175 — biophysics — Posted on 2024-07-16
2792 A rapid, accurate approach to inferring pedigrees in endogamous populations
Williams, C. M.; Scelza, B.; Slack, S. D.; Mathias, R. A.; Watson, H.; Barnes, K. C.; Lange, E.; Johnson, R. K.; Gignoux, C. R.; Ramachandran, S.; Henn, B. M.
10.1101/2020.02.25.965376 — bioinformatics — Posted on 2024-07-16
2794 Multi-scale Simulations Reveal Molecular Drivers in MUT-16 Scaffold Protein Phase Separations and Client Recognition
Gaurav, K.; Busetto, V.; Moscoso, D. J. P.; Changiarath, A.; Hanson, S. M.; Falk, S.; Ketting, R. F.; Stelzl, L. S.
10.1101/2024.04.13.589337 — bioinformatics — Posted on 2024-07-16
2795 Embryonic piRNAs target horizontally transferred vertebrate transposons in assassin bugs
Brito, T. F. d.; Cardoso, M. A.; Atinbayeva, N.; Brito, I. A. d. A.; da Costa, L. A.; Iovino, N.; Pane, A.
10.1101/2024.01.22.576481 — genomics — Posted on 2024-07-16
2796 The FIGNL1-FIRRM complex is required to complete meiotic recombination in the mouse and prevents massive DNA damage-independent RAD51 and DMC1 loading
Zainu, A.; Dupaigne, P.; Bouchouika, S.; Cau, J.; Clement, J. A. J.; Auffret, P.; Ropars, V.; Charbonnier, J.-B.; de Massy, B.; Mercier, R.; Kumar, R.; Baudat, F.
10.1101/2023.05.17.541096 — genetics — Posted on 2024-07-16
2801 Pressorum Sensing: Growth-induced Compression Activates cAMP Signaling in Pseudomonas aeruginosa
Ni, L.; Huang, Y.; Huang, Y.; Yu, Y.; Xiong, J.; Wen, H.; Xiao, W.; Liang, H.; Jin, F.
10.1101/2024.07.08.602437 — microbiology — Posted on 2024-07-16
2802 Event-Related Potential Markers of Subjective Cognitive Decline and Mild Cognitive Impairment during a sustained visuo-attentive task
Vergani, A. A.; Mazzeo, S.; Moschini, V.; Burali, R.; Lassi, M.; Amato, L. G.; Carpaneto, J.; Salvestrini, G.; Fabbiani, C.; Giacomucci, G.; Morinelli, C.; Emiliani, F.; Scarpino, M.; Bagnoli, S.; Ingannato, A.; Nacmias, B.; Padiglioni, S.; Sorbi, S.; Bessi, V.; Grippo, A.; Mazzoni, A.
10.1101/2024.01.30.577910 — neuroscience — Posted on 2024-07-16
2804 Astrocyte aquaporin mediates a tonic water efflux maintaining brain homeostasis
Pham, C.; Komaki, Y.; Deas-Just, A.; Le Gac, B.; Mouffle, C.; Franco, C.; Chaperon, A.; Vialou, V.; Tsurugizawa, T.; Cauli, B.; Li, D.
10.1101/2023.10.03.560471 — physiology — Posted on 2024-07-16
2806 Toxicological evaluation of Vanillin Flavor in E-Liquid Aerosols on Endothelial Cell Function: Findings from the Replica Project
Emma, R.; Sun, A.; Partsinevelos, K.; Rust, S.; Volarevic, V.; Lesmana, R.; Giordano, A.; Goenawan, H.; Barliana, M. I.; Arsenijevic, A.; Kastratovic, N.; Markovic, V.; Spasic, B.; Distefano, A.; Orlando, L.; Carota, G.; Polosa, R.; Caruso, M.; Li Volti, G.
10.1101/2024.01.20.576442 — pharmacology and toxicology — Posted on 2024-07-16
2807 Single-molecule live-cell RNA imaging with CRISPR-Csm
Xia, C.; Colognori, D.; Jiang, X.; Xu, K.; Doudna, J. A.
10.1101/2024.07.14.603457 — biophysics — Posted on 2024-07-16
2813 Limited protection against early-life cytomegalovirus infection results from deficiency of cytotoxic CD8T cells
Fonseca Brito, L.; Ostermann, E.; Perez, A.; Toedter, S.; Virdi, S.; Indenbirken, D.; Glau, L.; Gieras, A.; Brixel, R.; Arens, R.; Grundhoff, A.; Arck, P.; Diemert, A.; Tolosa, E.; Brune, W.; Stahl, F. R.
10.1101/2024.07.10.602923 — immunology — Posted on 2024-07-16
2814 Avirulence depletion assay: combining R gene-mediated selection with bulk sequencing for rapid avirulence gene identification in wheat powdery mildew
Kunz, L.; Jigisha, J.; Menardo, F.; Sotiropoulos, A. G.; Zbinden, H.; Zou, S.; Tang, D.; Hueckelhoven, R.; Keller, B.; Mueller, M. C.
10.1101/2024.07.10.602895 — plant biology — Posted on 2024-07-16
2822 Widespread parasite infections in living resident killer whales in the Northeast Pacific Ocean
Mastick, N. C.; Van Cise, A. M.; Parsons, K. M.; Ashe, E.; Williams, R.; Childress, J. N.; Fearnbach, H.; Durban, J.; Emmons, C.; Hanson, B.; Olsen, D.; Wood, C. L.
10.1101/2024.07.10.602791 — ecology — Posted on 2024-07-16
2823 EPHA1 and EPHB4 tyrosine kinase receptors regulate epithelial morphogenesis
Lavoie, N.; Scribe, A.; Chartier, F. J.; Ghani, K.; Jette, A.; Banerjee, S. L.; Caruso, M.; Laurin, M.; Freywald, A.; Elowe, S.; Laprise, P.; Bisson, N.
10.1101/2024.07.15.603563 — cell biology — Posted on 2024-07-16
2825 An off-lattice discrete model to characterise filamentous yeast colony morphology
Li, K.; Green, E.; Tronnolone, H.; Tam, A.; Black, A.; Gardner, J.; Sundstrom, J.; Jiranek, V.; Binder, B.
10.1101/2024.07.14.603473 — cell biology — Posted on 2024-07-16
2828 Small molecule FICD inhibitors suppress endogenous and pathologic FICD-mediated protein AMPylation
Chatterjee, B.; Alam, M.; Chakravorty, A.; Lacy, S.; Rech, J.; Brooks, C. L.; Arvan, P.; Truttmann, M.
10.1101/2024.07.13.603377 — cell biology — Posted on 2024-07-16
2833 Unbiased functional genetic screens reveal essential RNA modifications in human cancer and drug resistance
Pauli, C.; Kienhoefer, M.; Blank, M.; Begik, O.; Rohde, C.; Heid, D.; Xu, F.; Zimmermann, S. M. N.; Weidenauer, K.; Delaunay, S.; Krall, N.; Trunk, K.; Zhao, D.; Zhou, F.; Heit-Mondrzyk, A.; Platzbecker, U.; Baldus, C.; Serve, H.; Bornhaeuser, M.; Vagbo, C. B.; Aznar Benitah, S.; Krijgsveld, J.; Novoa, E. M.; Mueller-Tidow, C.; Frye, M.
10.1101/2024.07.13.603368 — cell biology — Posted on 2024-07-16
2834 Senescent cells cluster CTCF on nuclear speckles to sustain their splicing program
Palikyras, S.; Varamogianni-Mamatsi, V.; Zhu, Y.; Ramasamy, S.; Mizi, A.; Liebermann, I.; Stavropoulou, A.; Papadionysiou, I.; Bartsch, D.; Kargapolova, Y.; Sofiadis, K.; Nikolaou, C.; Kurian, L.; Oudelaar, M.; Barbieri, M.; Papantonis, A.
10.1101/2024.07.16.603680 — cell biology — Posted on 2024-07-16
2835 A linear ontogeny accounts for the development of naive, memory and tumour-infiltrating regulatory T cells in mice
Pathak, S.; Hogan, T.; rane, S.; Huang, Y.; Sinclair, C.; Barry, S.; Carnevalli, L.; Yates, A.; Seddon, B.
10.1101/2024.07.10.602914 — immunology — Posted on 2024-07-16
2836 A reaction norm for flowering time plasticity reveals physiological footprints of maize adaptation
Drouault, J.; Palaffre, C.; Millet, E. J.; Rodriguez, J.; Martre, P.; Johnson, K.; Parent, B.; Welcker, C.; Wisser, R. J.
10.1101/2024.07.10.602692 — plant biology — Posted on 2024-07-16
2838 Sequence-specific targeting of intrinsically disordered protein regions
Wu, K.; Jiang, H.; Hicks, D. R.; Liu, C.; Muratspahic, E.; Ramelot, T. A.; Liu, Y.; McNally, K.; Gaur, A.; Coventry, B.; Chen, W.; Bera, A. K.; Kang, A.; Gerben, S.; Lamb, M. Y.-L.; Murray, A.; Li, X.; Kennedy, M. A.; Yang, W.; Schober, G.; Brierley, S. M.; Gelb, M. H.; Montelione, G. T.; Derivery, E.; Baker, D.
10.1101/2024.07.15.603480 — biochemistry — Posted on 2024-07-16
2839 Actin dynamics sustains spatial gradients of membrane tension in adherent cells
Garcia-Arcos, J. M.; Mehidi, A.; Sanchez Velazquez, J.; Guillamat, P.; Tomba, C.; Houzet, L.; Capolupo, L.; D'Angelo, G.; Colom, A.; Hinde, E.; Aumeier, C.; Roux, A.
10.1101/2024.07.15.603517 — cell biology — Posted on 2024-07-16
2843 Physical activity modulates early visual response and improves target detection in humans
Weischner, T.; Che, X.; Schmid, P. R.; Reichert, C.; Scholz, A.; Knight, R. T.; Duerschmid, S.
10.1101/2024.07.10.602924 — neuroscience — Posted on 2024-07-16
2844 Preclinical validation and kinetic modelling of the SV2A PET ligand UCB-J in mice
Everix, L.; Elvas, F.; Miranda, A.; Khetarpal, V.; Liu, L.; Bard, J.; Staelens, S.; Bertoglio, D.
10.1101/2024.07.10.602899 — neuroscience — Posted on 2024-07-16
2851 Ancient tree-topologies and gene-flow processes among human lineages in Africa
Breton, G.; Sjodin, P.; Zervakis, P. I.; Laurent, R.; Froment, A.; Sjostrand, A. E.; Hewlett, B. S.; Barreiro, L. B.; Perry, G. H.; Soodyall, H.; Heyer, E.; Schlebusch, C. M.; Jakobsson, M.; Verdu, P.
10.1101/2024.07.15.603519 — genetics — Posted on 2024-07-16
2852 Improving biodiversity in Central and Eastern European domestic gardens needs regionally scaled strategies
Varga-Szilay, Z.; Barsevskis, A.; Benedek, K.; Bevk, D.; Jojczyk, A.; Kristin, A.; Ruzickova, J.; Jelaska, L. S.; Veromann, E.; Vilumets, S.; Fetyko, K.; Szovenyi, G.; Pozsgai, G.
10.1101/2024.07.12.603327 — ecology — Posted on 2024-07-16
2854 Emergent collective alignment gives competitive advantage to longer cells during range expansion
van den Berg, N.; Thijssen, K.; Nguyen, T. T.; Sarlet, A.; Cordero, M.; Vazquez, A. G.; Mitarai, N.; Doostmohammadi, A.; Jauffred, L.
10.1101/2024.01.26.577059 — biophysics — Posted on 2024-07-16
2855 Controlled and orthogonal partitioning of large particles into biomolecular condensates
Kelley, F.; Ani, A.; Pinlac, E.; Linders, B.; Favetta, B.; Barai, M.; Ma, Y.; Singh, A.; Dignon, G. L.; Gu, Y.; Schuster, B. S.
10.1101/2024.07.11.603072 — biophysics — Posted on 2024-07-16
2856 Effect of molecular weight of tyramine-modified hyaluronan on polarization state of THP-1 and peripheral blood mononuclear cells-derived macrophages
Wychowaniec, J. K.; Bektas, E. I.; Vernengo, A. J.; Mürner, M.; Airoldi, M.; Tipay, P. S.; Sapudom, J.; Teo, J.; Eglin, D.; D'Este, M.
10.1101/2024.01.11.575241 — bioengineering — Posted on 2024-07-16
2857 Glycosaminoglycans act as activators of peptidylarginine deiminase 4
Bereta, G. P.; Bielecka, E.; Marzec, K.; Pijanowski, L.; Biela, A.; Wilk, P.; Kaminska, M.; Nowak, J.; Wator, E.; Grudnik, P.; Kowalczyk, D.; Koziel, J.; Mydel, P.; Poreba, M.; Kantyka, T.
10.1101/2024.06.17.599283 — biochemistry — Posted on 2024-07-16
2858 Palaeoproteomic identification of a whale bone tool from Bronze Age Heiloo, the Netherlands
Dekker, J. A. A.; Mylopotamitaki, D.; Verbaas, A.; Sinet-Mathiot, V.; Presslee, S.; McCarthy, M. L.; Olsen, M. T.; Olsen, J. V.; van den Hurk, Y.; Brattinga, J.; Welker, F.
10.1101/2024.04.15.589626 — evolutionary biology — Posted on 2024-07-16
2861 Dimeric assembly of F1-like ATPase for Mycoplasma gliding motility
Toyonaga, T.; Kato, T.; Kawamoto, A.; Miyata, T.; Kawakami, K.; Fujita, J.; Hamaguchi, T.; Namba, K.; Miyata, M.
10.1101/2024.06.11.597861 — microbiology — Posted on 2024-07-16
2864 Uncertainty-Aware Traction Force Microscopy
Kandasamy, A.; Yeh, Y.-T.; Serrano, R.; Mercola, M.; del Alamo, J. C.
10.1101/2024.07.05.602172 — biophysics — Posted on 2024-07-16
2868 SARS-CoV-2 entry and fusion are independent of ACE2 localization to lipid rafts
Bolland, W.; Buchrieser, J.; Schwartz, O.; Casartelli, N.; Porrot, F.; Guivel-Benhassine, F.; Marechal, I.; Petiot, C.
10.1101/2024.07.13.603361 — microbiology — Posted on 2024-07-16
2869 Secondary metabolites and their impact on symbiotic interactions in the ambrosia fungus Geosmithia eupagioceri
Kolarik, M.; Stodulkova, E.; Kajzrova, S.; Semerad, J.; Hubert, J.; Kuzma, M.; Sulc, M.; Cisarova, I.; Jasica, A.; Wennrich, J.-P.; Hulcr, J.; Flieger, M.
10.1101/2024.07.15.603585 — microbiology — Posted on 2024-07-16
2870 Endogenous ZAP affects Zika virus RNA interactome
Sabir, A. J.; Le, N. P. K.; Singh, P. P.; Karniychuk, U.
10.1101/2024.05.23.595534 — microbiology — Posted on 2024-07-16
2871 Astrocyte-induced firing in primary afferent axons
Gaudel, F.; Giraud, J.; Morquette, P.; Couillard-Larocque, M.; Verdier, D.; Kolta, A.
10.1101/2024.06.07.597942 — neuroscience — Posted on 2024-07-16
2874 Rate variation and recurrent sequence errors in pandemic-scale phylogenetics
De Maio, N.; Willemsen, M.; Guo, Z.; Saha, A.; Hunt, M.; Ly-Trong, N.; Minh, B. Q.; Iqbal, Z.; Goldman, N.
10.1101/2024.07.12.603240 — bioinformatics — Posted on 2024-07-15
2875 Enzymatic carbon-fluorine bond cleavage by human gut microbes
Probst, S. I.; Felder, F. D.; Poltorak, V.; Mewalal, R.; Blaby, I. K.; Robinson, S. L.
10.1101/2024.07.15.601322 — biochemistry — Posted on 2024-07-15
2876 p16High immune cell - controlled disease tolerance as a broad defense and healthspan extending strategy
Triana-Martinez, F.; Pierantoni, A.; Graca, D.; Bergo, V.; Emelyanov, A.; Grigorash, B.; Tsuji, S.; Nakano, S.; Grosse, L.; Brglez, V.; Marty, P.; Dellamonica, J.; Fornace, A. J.; Trompouki, E.; Eiji, H.; Seitz-Polski, B.; Bulavin, D. V.
10.1101/2024.07.15.603540 — cell biology — Posted on 2024-07-15
2877 Molecular Landscape of Modality-Specific Exercise Adaptation in Human Skeletal Muscle through Large-Scale Multi-OMICs Integration
Jacques, M.; Landen, S.; Sharples, A. P.; Garnham, A.; Schittenhelm, R.; Stele, J.; Heikkinen, A.; Sillanpaa, E.; Ollikainen, M.; Broatch, J.; Zarekookandeh, N.; Hanson, O.; Ekstrom, O.; Asplund, O.; Lamon, S.; Alexander, S. E.; Smith, C.; Bauer, C.; Woessner, M. N.; Levinger, I.; Teschendorff, A. E.; Gillberg, L.; Blom, I.; Wulff Helge, J.; Harvey, N. R.; Haupt, L. M.; Griffiths, L. R.; Deshmukh, A. S.; Pietilainen, K. H.; Piirila, P.; Seaborne, R. A.; Jones-Freeman, B.; EYNON, N.
10.1101/2024.07.14.603458 — molecular biology — Posted on 2024-07-15
2878 The Splice Index as a prognostic biomarker of strength and function in myotonic dystrophy type 1
Provenzano, M.; Ikegami, K.; Bates, K.; Gaynor, A.; Hartman, J. M.; Jones, A. S.; Butler, A.; Berggren, K. N.; Dekdebrun, J.; Hung, M.; Lapato, D. M.; Kiefer, M.; Thornton, C.; Johnson, N. E.; Hale, M. A.
10.1101/2024.07.10.602610 — molecular biology — Posted on 2024-07-15
2883 Efficacy and mechanism of actions of cipargamin as an antibabesial drug candidate
Li, H.; Ji, S.; Ariefta, N. R.; Galon, E. M. S.; El-Sayed, S. A.; Jia, L.; Nishikawa, Y.; Liu, M.; Xuan, X.
10.1101/2024.07.15.603500 — microbiology — Posted on 2024-07-15
2885 Metabolic conservation by protein quality control in Campylobacter jejuni underlies the antibiotic tolerance
Feng, J.; Li, S.; Hu, Y.; Stahl, M.; Ma, L.; Knuff-Janzen, K.; Wang, K.; Hua, M. Z.; Vallance, B. A.; Konkel, M. E.; Finlay, B. B.; Lu, X.
10.1101/2024.07.15.603561 — microbiology — Posted on 2024-07-15
2886 Structural insight into sodium ion pathway in the bacterial flagellar stator from marine Vibrio
Nishikino, T.; Takekawa, N.; Kishikawa, J.-i.; Hirose, M.; Kojima, S.; Homma, M.; Kato, T.; Imada, K.
10.1101/2024.07.15.603494 — microbiology — Posted on 2024-07-15
2887 Electrochemical cofactor recycling of bacterial microcompartments
Sutter, M.; Utschig, L. M.; Niklas, J.; Paul, S.; Kahan, D. N.; Gupta, S.; Poluektov, O. G.; Ferlez, B.; Tefft, N. M.; TerAvest, M. A.; Hickey, D. P.; Vermaas, J. V.; Ralston, C. Y.; Kerfeld, C. A.
10.1101/2024.07.15.603600 — microbiology — Posted on 2024-07-15
2888 Biofilm dispersal patterns revealed using far-red fluorogenic probes
Prentice, J. A.; Kasivisweswaran, S.; van de Weerd, R.; Bridges, A. A.
10.1101/2024.07.15.603607 — microbiology — Posted on 2024-07-15
2890 Single-Cell and Spatial Transcriptomic Analyses Deciphering the Three-Layer Architecture of Human Tuberculosis Granulomas
Yu, X.; Wang, J.; Wang, P.; Liu, X.; Li, C.; Ju, Y.; Liu, S.; Dong, Y.; Wang, J.; Tuohetaerbaike, B.; Wen, H.; Zhang, W.; Niu, H.; Xu, S.; Jiang, C.; Jiang, X.; Wu, J.; Huang, H.; Chen, F.
10.1101/2024.07.15.603490 — microbiology — Posted on 2024-07-15
2891 The bacterial microbiome in Spider and Deathwatch beetles
Hendricks, A.; Philips, T. K.; Plarre, R.; Engl, T.; Martinson, V. G.
10.1101/2024.07.15.603335 — microbiology — Posted on 2024-07-15
2897 Physical Exercise Improves Working Memory through Ripple-Spindle Coupling
Che, X.; Auer, B.; Schmid, P.; Reichert, C.; Scholz, A.; Weischner, T.; Knight, R. T.; Duerschmid, S.
10.1101/2024.07.10.602896 — neuroscience — Posted on 2024-07-15
2898 Digital pathology assessment of kidney glomerular filtration barrier ultrastructure in an animal model of podocytopathy
Laudon, A. D.; Wang, Z.; Zou, A.; Sharma, R.; Ji, J.; Kim, C.; Qian, Y.; Ye, Q.; Chen, H.; Henderson, J. M.; Zhang, C.; Kolachalama, V. B.; Lu, W.
10.1101/2024.06.14.599097 — pathology — Posted on 2024-07-15
2903 Msh3 and Pms1 Set Neuronal CAG-repeat Migration Rate to Drive Selective Striatal and Cortical Pathogenesis in HD Mice
Wang, N.; Zhang, S.; Langfelder, P.; Ramanathan, L.; Plascencia, M.; Gao, F.; Vaca, R.; Gu, X.; Ferguson, L. D.; Dionisio, L. E.; Prasad, B. C.; Vogt, T. F.; Horvath, S.; Aaronson, J.; Rosinski, J.; Yang, X. W.
10.1101/2024.07.09.602815 — neuroscience — Posted on 2024-07-15
2904 Contextual AI models for single-cell protein biology
Li, M. M.; Huang, Y.; Sumathipala, M.; Liang, M. Q.; Valdeolivas, A.; Ananthakrishnan, A. N.; Liao, K.; Marbach, D.; Zitnik, M.
10.1101/2023.07.18.549602 — bioinformatics — Posted on 2024-07-15
2906 Comprehensive multi-site profiling of the malignant pleural mesothelioma micro-environment identifies candidate molecular determinants of histopathologic type
Severson, D. T.; Freyaldenhoven, S.; Wadowski, B.; Hughes, T.; Hung, Y. P.; Chirieac, L.; Jensen, R. V.; Richards, W. G.; Sedak, A. A.; Gustafson, C. E.; Vermilya, K.; Innocenti, S.; Korle, S.; Barlow, J. S.; Couger, M. B.; Anderson, J.; Meyervitz, J.; Wang, V.; Dao, M. N.; Shalek, A. K.; De Rienzo, A.; Bueno, R.
10.1101/2024.05.24.595690 — cancer biology — Posted on 2024-07-15
2908 Transcription Factors DksA and PsrA are synergistic contributors to L. pneumophila virulence in Acathamoeba castellanii protozoa
Graham, C. I.; Gierys, A. J.; MacMartin, T. L.; Penner, T. V.; Beck, J. C.; Prehna, G.; de Kievit, T. R.; Brassinga, A. K. C.
10.1101/2024.07.09.602712 — microbiology — Posted on 2024-07-15
2909 Mast Cell Derived Histamine Negatively Regulates Hematopoiesis
Klein, B. R.; Smith, J. N. P.; Katabathula, R.; Chaudhary, R.; Gao, Z.; Cordova, B. A.; Petroze, F.; Tiwari, R.; Gerson, S. L.; Xu, R.; Markowitz, S. D.; Desai, A. B.
10.1101/2022.02.03.479012 — immunology — Posted on 2024-07-15
2910 Oxidized LDL regulates efferocytosis through the CD36-PKM2-mtROS pathway
Zhang, J.; Chang, J.; Chen, V.; Beg, M. A.; Huang, W.; Vick, L.; Wang, Y.; Zhang, H.; Yttre, E.; Gupta, A.; Castleberry, M.; Zhang, Z.; Dai, W.; Song, S.; Zhu, J.; Yang, M.; Brown, A. K.; Xu, Z.; Ma, Y.-q.; Smith, B. C.; Zielonka, J.; Taylor, J. G.; Dhaou, C. B.; Orr, A. W.; Cui, W.; Zheng, Z.; Chen, Y.
10.1101/2023.09.07.556574 — immunology — Posted on 2024-07-15
2912 Longitudinal Multi-Tensor Analysis of Neocortical Microstructure in an Animal Model of Cortical Dysplasia
Villasenor, P. J.; Luna-Munguia, H.; Ramirez-Manzanares, A.; Coronado-Leija, R.; Concha, L.
10.1101/2024.07.09.602800 — neuroscience — Posted on 2024-07-15
2915 INF2-mediated actin polymerization at ER-organelle contacts regulates organelle size and movement
Schiavon, C. R.; Wang, Y.; Feng, J. W.; Garrett, S.; Dayn, Y.; Sung, T.-C.; Wang, C.; Youle, R. J.; Quintero-Carmona, O. A.; Shadel, G. S.; Manor, U.
10.1101/2024.07.06.602365 — cell biology — Posted on 2024-07-15
2916 CellPie: a scalable spatial transcriptomics factor discovery method via joint non-negative matrix factorization
Georgaka, S.; Morgans, W. G.; Zhao, Q.; Sanchez Martinez, D.; Ali, A.; Ghafoor, M.; Baker, S. M.; Bristow, R.; Iqbal, M.; Rattray, M.
10.1101/2023.09.29.560213 — bioinformatics — Posted on 2024-07-15
2917 Ongoing genome doubling promotes evolvability and immune dysregulation in ovarian cancer
McPherson, A. W.; Vazquez-Garcia, I.; Myers, M. A.; Zatzman, M.; Al-Rawi, D. H.; Weiner, A. C.; Freeman, S. S.; Mohibullah, N.; Satas, G.; Williams, M. J.; Ceglia, N.; Zhang, A. W.; Li, J.; Lim, J. L. P.; Wu, M.; Choi, S.; Havasov, E.; Grewal, D.; Shi, H.; Kim, M.; Schwarz, R. F.; Kaufmann, T. L.; Dinh, K. N.; Uhlitz, F.; Tran, J.; Wu, Y.; Patel, R.; Ramakrishnan, S.; Kim, D.; Clarke, J.; Green, H.; Ali, E.; DiBona, M.; Varice, N.; Kundra, R.; Broach, V.; Gardner, G. J.; Long Roche, K.; Sonoda, Y.; Zivanovic, O.; Kim, S. H.; Grisham, R. N.; Liu, Y. L.; Viale, A.; Rusk, N.; Lakhman, Y.; Ellenso
10.1101/2024.07.11.602772 — cancer biology — Posted on 2024-07-15
2920 Inhibitor-induced supercharging of kinase turnover via endogenous proteolytic circuits
Scholes, N. S.; Bertoni, M.; Comajuncosa-Creus, A.; Kladnik, K.; Frommelt, F.; Hinterndorfer, M.; Razumkov, H.; Prokofeva, P.; Schwalm, M. P.; Imrichova, H.; Barone, E.; Schätz, C.; Rukavina, A.; Koren, A.; Kubicek, S.; Knapp, S.; Gray, N. S.; Superti-Furga, G.; Küster, B.; Aloy, P.; Winter, G. E.
10.1101/2024.07.10.602881 — molecular biology — Posted on 2024-07-15
2921 Aperiodic activity as a central neural feature of hypnotic susceptibility outside of hypnosis
Landry, M.; da Silva Castanheira, J.; Boisvert, C.; Rousseaux, F.; Sackur, J.; Raz, A.; Ogez, D.; Rainville, P.; Jerbi, K.
10.1101/2023.11.16.567097 — neuroscience — Posted on 2024-07-15
2924 Deep learning-based aberration compensation improves contrast and resolution in fluorescence microscopy
Guo, M.; Wu, Y.; Hobson, C. M.; Su, Y.; Qian, S.; Krueger, E.; Christensen, R.; Kroeschell, G.; Bui, J.; Chaw, M.; Zhang, L.; Liu, J.; Hou, X.; Han, X.; Lu, Z.; Ma, X.; Zhovmer, A.; Combs, C.; Moyle, M.; Yemini, E.; Liu, H.; Liu, Z.; Benedetto, A.; La Riviere, P.; Colon-Ramos, D.; Shroff, H.
10.1101/2023.10.15.562439 — bioengineering — Posted on 2024-07-15
2926 Origin and stepwise improvement of vertebrate lungs
Li, Y.; Hu, M.; Zhang, Z.; Wu, B.; Zheng, J.; Zhang, F.; Hao, J.; Xue, T.; Li, Z.; Zhu, C.; Zhao, L.; Xu, W.; Xin, P.; Feng, C.; Wang, W.; Zhao, Y.; Qiu, Q.; wang, K.
10.1101/2024.07.14.603411 — evolutionary biology — Posted on 2024-07-15
2930 Membrane potential as master regulator of cellular mechano-transduction
Mukherjee, A.; Huang, Y.; Elgeti, J.; Oh, S.; Abreu, J.; Neliat, A. R.; Schuttler, J.; Su, D.; Dupre, C.; Benites, N. C.; Liu, X.; Peshkin, L.; Barboiu, M.; Stocker, H.; Kirschner, M. W.; Basan, M.
10.1101/2023.11.02.565386 — cell biology — Posted on 2024-07-15
2934 The interplay of uncertainty, relevance and learning influences auditory categorization
Sheth, J.; Collina, J.; Piasini, E.; Kording, K. P.; Cohen, Y.; Geffen, M. N.
10.1101/2022.12.01.518777 — neuroscience — Posted on 2024-07-15
2935 Agrobacterium-mediated Cuscuta campestris transformation as a tool for understanding plant-plant interactions
Adhikari, S.; Mudalige, A.; Phillips, L.; Lee, H.; Bernal, V.; Gruszewski, H.; Westwood, J.; Park, S.-Y.
10.1101/2024.02.23.581736 — plant biology — Posted on 2024-07-15
2940 Distinct Excitability Properties of Cardiac Calbindin Neurons: Identifying a Unique Neuronal Population
Lizot, G.; Bescond, J.; De Koninck, Y.; Chahine, M.; Bois, P.; Faivre, J.-F.; Chatelier, A.
10.1101/2024.05.31.596786 — physiology — Posted on 2024-07-15
2941 A Myelin Map of Trunk Folds in the Elephant Trigeminal Nucleus
Reveyaz, N.; Schneeweiss, U.; Heise, O.; Gerhardt, B.; Gui, A. M.; Kaufmann, L. V.; Alfken, J.; Reichmann, J.; Salditt, T.; Hildebrandt, T. B.; Brecht, M.
10.1101/2023.11.15.567239 — neuroscience — Posted on 2024-07-15
2944 Molecular chaperone BiP controls activity of the ER stress sensor Ire1 through interactions with its oligomers
Dawes, S.; Hurst, N.; Grey, G.; Wieteska, L.; Wright, N. V.; Manfield, I. W.; Hussain, M. H.; Kalverda, A. P.; Lewandowski, J. R.; Chen, B.; Zhuravleva, A.
10.1101/2024.02.16.579620 — biophysics — Posted on 2024-07-15
2945 Developmental stage determines the realized energy landscape for a flight specialist
Nourani, E.; Faure, L.; Bronnvik, H.; Scacco, M.; Bassi, E.; Fiedler, W.; Gruebler, M. U.; Hatzl, J. S.; Jenny, D.; Roverselli, A.; Sumasgutner, P.; Tschumi, M.; Wikelski, M.; Safi, K.
10.1101/2023.09.07.556633 — animal behavior and cognition — Posted on 2024-07-15
2946 The regulatory grammar of human promoters uncovered by MPRA-trained deep learning
Barbadilla-Martinez, L.; Klaassen, N. H.; Franceschini-Santos, V. H.; Breda, J.; Hernandez-Quiles, M.; van Lieshout, T.; Urzua Traslavina, C. G.; Yücel, H.; Boi, M. C. L.; Hermana-Garcia-Agullo, C.; Gregoricchio, S.; Zwart, W. H.; Voest, E.; Franke, L.; Vermeulen, M.; de Ridder, J.; van Steensel, B.
10.1101/2024.07.09.602649 — genetics — Posted on 2024-07-15
2949 Cortical sensory aging is layer-specific
Liu, P.; Doehler, J.; Henschke, J. U.; Northall, A.; Serian, A.; Loaiza-Carvajal, L. C.; Budinger, E.; Schwarzkopf, D. S.; Speck, O.; Pakan, J. M. P.; Kuehn, E.
10.1101/2023.12.01.567841 — neuroscience — Posted on 2024-07-15
2952 Longitudinal Multi-Tensor Analysis of Neocortical Microstructure in an Animal Model of Cortical Dysplasia
Villasenor, P. J.; Luna-Munguia, H.; Ramirez-Manzanares, A.; Coronado-Leija, R.; Concha, L.
10.1101/2024.07.09.602800 — neuroscience — Posted on 2024-07-15
2953 Emergence of cellular nematic order is a conserved feature of gastrulation in animal embryos
Li, X.; Huebner, R. J.; Williams, M. L. K.; Sawyer, J.; Peifer, M.; Wallingford, J. B.; Thirumalai, D.
10.1101/2024.07.11.603175 — developmental biology — Posted on 2024-07-15
2957 Induction and characterisation of Abeta and tau pathology in AppNL-F/NL-F mice following inoculation with Alzheimer's disease brain homogenate
Purro, S. A.; Farmer, M.; Quarterman, E.; Ravey, J.; Thomas, D. X.; Noble, E.; Turnbull, C.; Linehan, J.; Nazari, T.; Brandner, S.; Farrow, M. A.; Walsh, D. M.; Collinge, J.
10.1101/2024.07.11.602448 — neuroscience — Posted on 2024-07-15
2959 Nitration of a ribosomal pentapeptide generates a noncanonical precursor for nonribosomal peptide synthesis
Padva, L.; Zimmer, L.; Gullick, J.; Zhao, Y.; Sasi, V. M.; Schittenhelm, R. B.; Jackson, C. J.; Cryle, M. J.; Cruesemann, M.
10.1101/2024.07.12.603347 — biochemistry — Posted on 2024-07-14
2960 Interchromosomal segmental duplication drives translocation and loss of P. falciparum histidine-rich protein 3
Hathaway, N. J.; Kim, I. E.; Young, N. W.; Hui, S. T.; Crudale, R.; Giesbrecht, D.; Liang, E. Y.; Nixon, C. P.; Juliano, J. J.; Parr, J. B.; Bailey, J. A.
10.1101/2022.12.07.519189 — genomics — Posted on 2024-07-14
2967 Recording γ-secretase activity in living mouse brains
Hou, S. S.; Ikegawa, Y.; Kwon, Y.; Wieckiewicz, N.; Houser, M. C. Q.; Lundin, B.; Bacskai, B. J.; Berezovska, O.; Maesako, M.
10.1101/2024.01.31.578105 — neuroscience — Posted on 2024-07-14
2969 NF-κB Epigenetic Attractor Landscape Drives Breast Cancer Heterogeneity
Lopes, F. J. P.; Pires, B. R. B.; Lima, A. A. B.; Binato, R.; Abdelhay, E.
10.1101/2024.07.10.602798 — systems biology — Posted on 2024-07-14
2970 Programmable promoter editing for precise control of transgene expression
Kabaria, S. R.; Bae, Y.; Ehmann, M. E.; Beitz, A. M.; Lende-Dorn, B. A.; Peterman, E. L.; Love, K. S.; Ploessl, D. S.; Galloway, K. E.
10.1101/2024.06.19.599813 — synthetic biology — Posted on 2024-07-14
2971 Single-cell resolved differentiation of pre-Kranz anatomy in maize leaf primordia
Yi, J.; Su, H.; Tian, S.; Sedelnikova, O.; Chen, Y.; Zhao, C.; Yang, J.; Zhang, Y.; Zhu, X.-G.; Langdale, J.; Wang, J.; Wang, P.
10.1101/2024.07.10.602848 — plant biology — Posted on 2024-07-14
2972 A Receptor Like Cytoplasmic Kinase evolved in Aeschynomene legumes to mediate Nod-independent rhizobial symbiosis
Horta Araujo, N.; Landry, D.; Quilbe, J.; Pervent, M.; Klopp, C.; Nouwen, N.; Racoupeau, M.; Gully, D.; Rios, M.; Brottier, L.; Pichereaux, C.; Gressent, F.; Chaintreuil, C.; Gough, C.; Giraud, E.; Lefebvre, B.; ARRIGHI, J.-F.
10.1101/2024.07.10.602847 — plant biology — Posted on 2024-07-14
2975 The regulatory potential of transposable elements in maize
Bubb, K. L.; Hamm, M. O.; Min, J. K.; Ramirez-Corona, B.; Mueth, N. A.; Ranchalis, J.; Vollger, M. R.; Trapnell, C.; Cuperus, J. T.; Queitsch, C.; Stergachis, A. B.
10.1101/2024.07.10.602892 — genomics — Posted on 2024-07-14
2978 VIRAL METAGENOMIC SURVEY OF CASPIAN SEALS
Karamendin, K.; Goodman, S. J.; Kasymbekov, Y.; Kumar, M.; Nuralibekov, S.; Kydyrmanov, A.
10.1101/2024.07.14.603418 — microbiology — Posted on 2024-07-14
2979 A new pathway in central metabolism mediates nutrient control of development and antibiotic production by Streptomyces
Li, C.; Urem, M.; Kotsogianni, I.; Lau, j.; Elsayed, S. S.; Martin, N. I.; McNae, I.; Voskamp, P.; Mayer, C.; Rigali, S.; Pannu, N.; Abrahams, J.-P.; Schada von Borzyskowski, L.; van Wezel, G. P.
10.1101/2024.07.14.603434 — microbiology — Posted on 2024-07-14
2980 Integrative deep immune profiling of the elderly reveals systems-level signatures of aging, sex, smoking, and clinical traits
Riemann, L.; Gutierrez, R.; Odak, I.; Barros-Martins, J.; Roesner, L. M.; Leon Lara, X.; Falk, C.; Schulz, T. F.; Hansen, G.; Werfel, T.; Foerster, R.
10.1101/2024.07.10.602828 — immunology — Posted on 2024-07-14
2981 Spurious correlations in surface-based functional brain imaging
Jeganathan, J.; Koussis, N. C.; Paton, B.; L, S. M.; Zalesky, A.; Breakspear, M.
10.1101/2024.07.09.602799 — neuroscience — Posted on 2024-07-14
2982 Connectome predictive modeling of trait mindfulness
Treves, I. N.; Kucyi, A.; Park, M.; Kral, T. R. A.; Goldberg, S. B.; Davidson, R. J.; Rosenkranz, M.; Whitfield-Gabrieli, S.; Gabrieli, J. D. E.
10.1101/2024.07.09.602725 — neuroscience — Posted on 2024-07-14
2983 AgRP1 modulates breeding season-dependent feeding behavior in female medaka
Tagui, Y.; Takeda, S.; Waida, H.; Kitahara, S.; Kimura, T.; Kanda, S.; Oka, Y.; Hayashi, Y.; Umatani, C.
10.1101/2024.07.10.602830 — neuroscience — Posted on 2024-07-14
2986 Preimaginal development of Aedes aegypti in brackish water produces adult mosquitoes with thicker cuticles and greater insecticide resistance
Ramasamy, R.; Sivabalakrishnan, K.; Hemphill, A.; Karunaratne, P.; Naguleswaran, A.; Roditi, I.; Surendran, S. N.
10.1101/2024.07.10.602862 — zoology — Posted on 2024-07-14
2988 FUSION: A web-based application for in-depth exploration of multi-omics data with brightfield histology
Border, S.; Melo Ferreira, R.; Lucarelli, N.; Kumar, S.; Paul, A.; Manthey, D.; Barisoni, L.; Strekalova, Y.; Ray, J.; Cheng, Y.-H.; Rosenberg, A. Z.; Tomaszewski, J. E.; Mimar, S.; Hodgin, J. B.; HuBMAP consortium, ; El-Achkar, T. M.; Jain, S.; Eadon, M. T.; Sarder, P.
10.1101/2024.07.09.602778 — pathology — Posted on 2024-07-14
2989 Acetate drives ovarian cancer quiescence via ACSS2-mediated acetyl-CoA production
Sharrow, A. C.; Megill, E.; Chen, A. J.; Farooqi, A.; McGonigal, S.; Hempel, N. W.; Snyder, N. W.; Buckanovich, R. J.; Aird, K. M.
10.1101/2024.07.12.603313 — cancer biology — Posted on 2024-07-14
2990 Quantifying "just-right" APC inactivation for colorectal cancer initiation
Brunet Guasch, M.; Feeley, N.; Soriano, I.; Thorn, S. B.; Tomlinson, I.; Nicholson, M.; Antal, T.
10.1101/2024.07.10.602868 — cancer biology — Posted on 2024-07-14
2991 Discovery and Repurposing of Multi-Target Senolytics through Structure-Based Virtual Screening
Olacoaga, S.; Königsberg, M.; Cortes-Benitez, F.; Perez-Villanueva, J.; Lopez-Diazguerrero, N. E.
10.1101/2024.07.09.602796 — bioinformatics — Posted on 2024-07-14
2994 Flexible neural representations of abstract structural knowledge in the human Entorhinal Cortex
Mark, S.; Baram, A.; Schwartenbeck, P.; Hahamy, A.; Samborska, V.; Behrens, T. E. J.
10.1101/2023.08.31.555760 — neuroscience — Posted on 2024-07-14
2995 Orthology inference at scale with FastOMA
Majidian, S.; Nevers, Y.; Yazdizadeh Kharrazi, A.; Warwick Vesztrocy, A.; Pascarelli, S.; Moi, D.; Glover, N.; Altenhoff, A. M.; Dessimoz, C.
10.1101/2024.01.29.577392 — bioinformatics — Posted on 2024-07-14
2999 Rapid evolution of gene expression patterns in flowering plants
Schuster, C.; Gabel, A.; Drost, H.-G.; Grosse, I.; Leyser, O.; Meyerowitz, E. M.
10.1101/2024.07.08.602577 — plant biology — Posted on 2024-07-14
3000 Doubling the resolution of fluorescence-lifetime single-molecule localization microscopy with image scanning microscopy
Radmacher, N.; Nevskyi, O.; Gallea, J. I.; Thiele, J. C.; Gregor, I.; Rizzoli, S. O.; Enderlein, J.
10.1101/2023.08.23.554438 — biophysics — Posted on 2024-07-14
3001 Distinct representation of locomotive action affordances in human behavior, brains and deep neural networks
Bartnik, C. G.; Sartzetaki, C.; Puigseslloses Sanchez, A.; Molenkamp, E.; Bommer, S.; Vuksic, N.; Groen, I. I. A.
10.1101/2024.05.15.594298 — neuroscience — Posted on 2024-07-14
3002 Evaluation of a Real-time Plasmid Transmission Detection Pipeline
Scherff, N.; Rothgänger, J.; Weniger, T.; Mellmann, A.; Harmsen, D.
10.1101/2024.07.09.602722 — bioinformatics — Posted on 2024-07-14
3003 E2VD: a unified evolution-driven framework for virus variation drivers prediction
Nie, Z.; Liu, X.; Chen, J.; Wang, Z.; Liu, Y.; Si, H.; Dong, T.; Xu, F.; Song, G.; Wang, Y.; Zhou, P.; Gao, W.; Tian, Y.
10.1101/2023.11.27.568815 — bioinformatics — Posted on 2024-07-14
3008 Exercise training at different intensities induces heat stress, disrupts barrier function and alters microbiota in the gut of mice
Lian, P.; Kovynev, A.; Wang, L.; Pronk, A. C. M.; Verhoeven, A.; Giera, M.; Thijssen, S.; Martinez Tellez, B.; Kooijman, S.; Rensen, P. C.; Timmerman, H.; Wichers, H. J.; Henricks, P. A. J.; Folkerts, G.; Schonke, M.; Braber, S.
10.1101/2024.07.10.602866 — physiology — Posted on 2024-07-14
3009 Expansion of mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis
Jaquish, A.; Phung, E.; Gong, X.; Baldominos, P.; Galvan-Pena, S.; Bursulaya, I.; Magill, I.; ImmgenT consortium, ; Bertrand, K.; Chambers, C.; Agudo, J.; Mathis, D.; Benoist, C.; Ramanan, D.
10.1101/2024.07.09.602739 — immunology — Posted on 2024-07-13
3011 Neuron synchronization analyzed through spatial-temporal attention
Yang, H.; KC, P.; Chen, P.; Lei, H.; Sponberg, S.; Tarokh, V.; Riffell, J.
10.1101/2024.07.10.602834 — neuroscience — Posted on 2024-07-13
3012 From histology to macroscale function in the human amygdala
Auer, H.; Cabalo, D. G.; Rodriguez-Cruces, R.; Benkarim, O.; Paquola, C.; Dekraker, J.; Wang, Y.; Valk, S. L.; Bernhardt, B.; Royer, J.
10.1101/2024.07.09.602743 — neuroscience — Posted on 2024-07-13
3014 Enhancing Retrieval Capacity of the Predictive Brain through Dorsolateral Prefrontal Cortex Intervention
Szucs-Bencze, L.; Vekony, T.; Pesthy, O.; Kocsis, K.; Kincses, Z. T.; Szabo, N.; Nemeth, D.
10.1101/2024.07.10.602829 — neuroscience — Posted on 2024-07-13
3015 Post-weaning social isolation alters sociability in a sex-specific manner
Myers, T.; Birmingham, E. A.; Rhoads, B. T.; McGrath, A. G.; Miles, N. A.; Schuldt, C. B.; Briand, L. A.
10.1101/2024.07.11.603129 — neuroscience — Posted on 2024-07-13
3018 Kupffer cell and recruited macrophage heterogeneity orchestrate granuloma maturation and hepatic immunity in visceral leishmaniasis
Pessenda, G.; Ferreira, T. R.; Paun, A.; Kabat, J.; Amaral, E. P.; Kamenyeva, O.; Gazzinelli-Guimaraes, P. H.; Perera, S. R.; Ganesan, S.; Lee, S. H.; Sacks, D. L.
10.1101/2024.07.09.602717 — immunology — Posted on 2024-07-13
3021 Msh3 and Pms1 Set Neuronal CAG-repeat Migration Rate to Drive Selective Striatal and Cortical Pathogenesis in HD Mice
Wang, N.; Zhang, S.; Langfelder, P.; Ramanathan, L.; Plascencia, M.; Gao, F.; Vaca, R.; Gu, X.; Ferguson, L. D.; Dionisio, L. E.; Prasad, B. C.; Vogt, T. F.; Horvath, S.; Aaronson, J.; Rosinski, J.; Yang, X. W.
10.1101/2024.07.09.602815 — neuroscience — Posted on 2024-07-13
3022 Sex-related differences in vascular remodeling of sodium overloaded normotensive mice
Silva, J. C. d. S.; Viegas, K. A. d. S.; Lima, R. S. d.; Lima, C. T.; Peron, N. N.; Silva, M. B. d.; Irigoyen, M. C.; Lacchini, S.
10.1101/2024.07.09.602349 — physiology — Posted on 2024-07-13
3023 Accurate isoform quantification by joint short- and long-read RNA-sequencing
Apostolides, M.; Choi, B.; Navickas, A.; Saberi, A.; Soto, L. M.; Goodarzi, H.; Najafabadi, H. S.
10.1101/2024.07.11.603067 — bioinformatics — Posted on 2024-07-13
3024 Silicon Nitride Induces Osteoconduction Via Activated Mitochondrial Oxidative Phosphorylation and Neovascularization
Gonzales, W. D.; Khade, R.; Kondo, T.; Arimoto, S.; Inagaki, T.; Hokugo, A.; Kaczor-Urbanowicz, K. E.; McEntire, B.; Bock, R. M.; Ogawa, T.; Pezzotti, G.; Nishimura, I.
10.1101/2024.07.09.602787 — bioengineering — Posted on 2024-07-13
3031 METTL3 shapes m6A epitranscriptomic landscape for successful human placentation
Kumar, R. P.; Kumar, R.; Ganguly, A.; Ghosh, A.; Ray, S.; Islam, M. R.; Saha, A.; Roy, N.; Dasgupta, P.; Knowles, T.; Niloy, A. J.; Marsh, C.; Paul, S.
10.1101/2024.07.12.603294 — developmental biology — Posted on 2024-07-13
3032 Multisite Assembly of Gateway Induced Clones (MAGIC): a flexible cloning toolbox withdiverse applications in vertebrate model systems.
Gillespie, W.; Zhang, Y.; Ruiz, O. E.; Cerda, J.; Ortiz-Guzman, J.; Turner, W. D.; Largoza, G.; Sherman, M.; Mosser, L. E.; Fujimoto, E.; Chien, C.-B.; Kwan, K. M.; Arenkiel, B. R.; Devine, W. P.; Wythe, J.
10.1101/2024.07.13.603267 — molecular biology — Posted on 2024-07-13
3033 Mitigating sTNF/TNFR1 activation on VGluT2+ spinal cord interneurons improves immune function after mid-thoracic spinal cord injury
Martynyuk, T.; Ricard, J.; Bracchi-Ricard, V.; Price, S.; McGrath, J.; Dougherty, K.; Tom, V.; Bethea, J. R.
10.1101/2024.07.09.602690 — neuroscience — Posted on 2024-07-13
3036 Ongoing genome doubling promotes evolvability and immune dysregulation in ovarian cancer
McPherson, A. W.; Vazquez-Garcia, I.; Myers, M. A.; Zatzman, M.; Al-Rawi, D. H.; Weiner, A. C.; Freeman, S. S.; Mohibullah, N.; Satas, G.; Williams, M. J.; Ceglia, N.; Zhang, A. W.; Li, J.; Lim, J. L. P.; Wu, M.; Choi, S.; Havasov, E.; Grewal, D.; Shi, H.; Kim, M.; Schwarz, R. F.; Kaufmann, T. L.; Dinh, K. N.; Uhlitz, F.; Tran, J.; Wu, Y.; Patel, R.; Ramakrishnan, S.; Kim, D.; Clarke, J.; Green, H.; Ali, E.; DiBona, M.; Varice, N.; Kundra, R.; Broach, V.; Gardner, G. J.; Long Roche, K.; Sonoda, Y.; Zivanovic, O.; Kim, S. H.; Grisham, R. N.; Liu, Y. L.; Viale, A.; Rusk, N.; Lakhman, Y.; Ellenso
10.1101/2024.07.11.602772 — cancer biology — Posted on 2024-07-13
3038 Pymportx: Facilitating Next-Generation Transcriptomics Analysis in Python
Pena Gonzalez, P.; Lozano-Paredes, D.; Rojo, J. L.; Bote-Curiel, L.; Sanchez-Arevalo Lobo, V. J.
10.1101/2024.07.12.598873 — bioinformatics — Posted on 2024-07-13
3039 Enhanced sensitivity of TAPscan v4 enables comprehensive analysis of streptophyte transcription factor evolution
Petroll, R.; Varshney, D.; Hiltemann, S.; Finke, H.; Schreiber, M.; de Vries, J.; Rensing, S. A.
10.1101/2024.07.13.602682 — bioinformatics — Posted on 2024-07-13
3041 Ribosomal DNA arrays are the most H-DNA rich element in the human genome
Chantzi, N.; Patsakis, M.; Nayak, A.; Montgomery, A.; Mouratidis, I.; Georgakopoulos Soares, I.
10.1101/2024.07.12.602585 — genomics — Posted on 2024-07-13
3042 Structural variants underlie parallel adaptation following global invasion
Battlay, P.; Hendrickson, B. T.; Mendez-Reneau, J. I.; Santangelo, J. S.; Albano, L. J.; Wilson, J.; Caizergues, A. E.; King, N.; Puentes, A.; Tudoran, A.; Violle, C.; Vasseur, F.; Patterson, C. M.; Foster, M. J.; Stamps, C.; Innes, S. G.; Allio, R.; Angeoletto, F.; Anstett, D. N.; Anstett, J.; Bucharova, A.; Comerford, M. S.; David, S.; Falahati Anbaran, M.; Godsoe, W.; Gonzalez-Lagos, C.; Gundel, P. E.; Hood, G. R.; Karousou, R.; Lampei, C.; Lara, C.; Lazaro-Lobo, A.; Leandro, D.; Merritt, T. J.; Mitchell, N.; Mohammadi Bazargani, M.; Moles, A.; Murua, M.; Paule, J.; Pfeiffer, V.; Raeymaeker
10.1101/2024.07.09.602765 — evolutionary biology — Posted on 2024-07-13
3043 PP1 PNUTS binds the restrictor and dephosphorylates RNA pol II CTD Ser5 to stimulate transcription termination
Bentley, D.; Treisman, R.; Erickson, B.; Fong, N.; Hansen, K.; Sheridan, R. M.; Larson, K.; Saviola, A.; Fedoryshchak, R.; Mouilleron, S.
10.1101/2024.07.12.603302 — molecular biology — Posted on 2024-07-13
3044 Bioenergetic stress potentiates antimicrobial resistance and persistence
Li, B.; Srivastava, S.; Shaikh, M.; Mereddy, G.; Garcia, M. R.; Shah, A.; Ofori-Anyinam, N.; Chu, T.-Y.; Cheney, N.; Yang, J. H.
10.1101/2024.07.12.603336 — microbiology — Posted on 2024-07-13
3045 LRRK2 kinase activity restricts NRF2-dependent mitochondrial protection in microglia
Weindel, C. G.; Ellzey, L. M.; Coleman, A. K.; Patrick, K. L.; Watson, R. O.
10.1101/2024.07.09.602769 — immunology — Posted on 2024-07-13
3046 IL-21 Shapes the B Cell Response in a Context-Dependent Manner
Kim, Y.; Manara, F.; Grassmann, S.; Belcheva, K.; Reyes, K.; Kim, H.; Downs-Canner, S.; Yewdell, W. T.; Sun, J. C.; Chaudhuri, J.
10.1101/2024.07.13.600808 — immunology — Posted on 2024-07-13
3048 Chronic β3 adrenergic agonist treatment improves brain microvascular endothelial function and cognition in aged mice
Natarajan, D.; Ekambaram, S.; Tarantini, S.; Yelahanka Nagaraja, R.; Yabluchanskiy, A.; Hendrik, A.; Awasthi, V.; Subramanian, M.; Csiszar, A.; Balasubramanian, P.
10.1101/2024.07.09.602747 — neuroscience — Posted on 2024-07-13
3050 PyINETA: Open-source platform for INADEQUATE-JRES integration in NMR metabolomics
Taujale, R.; Uchimiya, M.; Clendinen, C. S.; Borges, R. M.; Turck, C. W.; Edison, A. S.
10.1101/2024.07.10.601875 — systems biology — Posted on 2024-07-13
3051 The penetration ring is a novel infection structure formed by the penetration peg for invading plant cell membrane in rice blast fungus
Fang, W.; Zai, X.; Chen, J.; Abubakar, Y. S.; Wu, Q.; Fang, Z.; Huang, X.; Gan, X.; Ebbole, D. J.; Wang, Z.; Zheng, W.
10.1101/2024.07.11.603048 — pathology — Posted on 2024-07-13
3054 STRPsearch: fast detection of structured tandem repeat proteins
Mozaffari, S.; Arrias, P. N.; Clementel, D.; Piovesan, D.; Ferrari, C.; Tosatto, S. C. E.; Monzon, A. M.
10.1101/2024.07.10.602726 — bioinformatics — Posted on 2024-07-13
3060 Genomic insights into red squirrels in Scotland reveals loss of heterozygosity associated with extreme founder effects
Marr, M. M.; Humble, E.; Lurz, P. W. W.; Wilson, L. A.; Milne, E.; Beckmann, K. M.; Schoenebeck, J.; Fung, U.-Y.-Y.; Kitchener, A. C.; Kortland, K.; Edwards, C.; Ogden, R.
10.1101/2024.07.10.602565 — genomics — Posted on 2024-07-13
3061 An updated DNA barcoding tool for Aloe vera and related CITES-regulated species
Woudstra, Y.; Rees, P.; Rakotoarisoa, S. E.; Roensted, N.; Howard, C.; Grace, O. M.
10.1101/2024.07.09.602761 — genomics — Posted on 2024-07-13
3062 Transposable element accumulation drives genome size increase in Hylesia metabus (Lepidoptera: Saturniidae), an urticating moth species from South America
Perrier, C.; Allio, R.; Legeai, F.; Gautier, M.; Beneluz, F.; Marande, W.; Theron, A.; Rodde, N.; Herrera, M.; Saune, L.; Parrinello, H.; McClure, M.; Arias, M.
10.1101/2024.07.11.602864 — genomics — Posted on 2024-07-13
3063 Cryptic diversity shapes coral symbioses, physiology, and response to thermal challenge
Aichelman, H. E.; Benson, B. E.; Gomez-Campo, K.; Martinez-Rugerio, M. I.; Fifer, J. E.; Tsang, L.; Hughes, A. M.; Bove, C. B.; Nieves, O. C.; Pereslete, A. M.; Stanizzi, D.; Kriefall, N. G.; Baumann, J. H.; Rippe, J. P.; Gondola, P.; Castillo, K. D.; Davies, S. W.
10.1101/2024.07.09.602709 — evolutionary biology — Posted on 2024-07-13
3064 Ideal efficacy photoswitches for TRPC4/5 channels harness high potency for spatiotemporally-resolved control of TRPC function in live tissues
Müller, M.; Niemeyer, K.; Ojha, N. K.; Porav, S. A.; Vinayagam, D.; Urban, N.; Büchau, F.; Oleinikov, K.; Makke, M.; Bauer, C. C.; Johnson, A. V.; Muench, S. P.; Zufall, F.; Bruns, D.; Schwarz, Y.; Raunser, S.; Leinders-Zufall, T.; Bon, R. S.; Schaefer, M.; Thorn-Seshold, O.
10.1101/2024.07.12.602451 — cell biology — Posted on 2024-07-13
3065 Follicle stimulating hormone receptor expression in human pancreas and effects on insulin secretion: A translational study
Aydin, B. K.; Incedal Nilsson, C.; Chowdhury, A.; Wen, Q.; Cerenius, S. Y.; Stenlid, R.; Morwald, K.; Ciba, I.; Manell, H.; Weghuber, D.; Forslund, A.; Idevall-Hagren, O.; Bergsten, P.
10.1101/2024.07.12.603223 — cell biology — Posted on 2024-07-13
3066 An INS-1 beta-cell proteome highlights the role of fatty acid biosynthesis in glucose-stimulated insulin secretion
Stremmel, N.; Lemke, O.; Textoris-Taube, K.; Ludwig, D.; Muelleder, M.; Muenzner, J.; Ralser, M.
10.1101/2024.07.12.603204 — cell biology — Posted on 2024-07-13
3067 Experimental reproduction of viral replication and disease in dairy calves and lactating cows inoculated with highly pathogenic avian influenza H5N1 clade 2.3.4.4b
Baker, A. L.; Arruda, B.; Palmer, M. V.; Boggiatto, P.; Sarlo Davila, K.; Buckley, A.; Ciacci Zanella, G.; Snyder, C. A.; Anderson, T. K.; Hutter, C.; Nguyen, T.-Q.; Markin, A.; Lantz, K.; Posey, E. A.; Torchetti, M. K.; Robbe-Austerman, S.; Magstadt, D. R.; Gorden, P. J.
10.1101/2024.07.12.603337 — microbiology — Posted on 2024-07-13
3068 Endemism shapes viral ecology and evolution in globally distributed hydrothermal vent ecosystems
Langwig, M. V.; Koester, F.; Martin, C.; Zhou, Z.; Joye, S. B.; Reysenbach, A.-L.; Anantharaman, K.
10.1101/2024.07.12.603268 — microbiology — Posted on 2024-07-13
3074 "Micro-offline gains" convey no benefit for motor skill learning
Das, A.; Karagiorgis, A.; Diedrichsen, J.; Stenner, M.-P.; Azanon, E.
10.1101/2024.07.11.602795 — neuroscience — Posted on 2024-07-13
3080 OpenTn5: Open-Source Resource for Robust and Scalable Tn5 Transposase Purification and Characterization
Soroczynski, J.; Anderson, L. J.; Yeung, J. L.; Rendleman, J. M.; Oren, D. A.; Konishi, H. A.; Risca, V. I.
10.1101/2024.07.11.602973 — genomics — Posted on 2024-07-13
3081 Resolving the chromatin impact of mosaic variants with targeted Fiber-seq
Bohaczuk, S. C.; Amador, Z. J.; Li, C.; Mallory, B. J.; Swanson, E. G.; Ranchalis, J.; Vollger, M. R.; Munson, K. M.; Walsh, T.; Hamm, M. O.; Mao, Y.; Lieber, A.; Stergachis, A. B.
10.1101/2024.07.09.602608 — genomics — Posted on 2024-07-13
3085 Single influenza A viruses induce nanoscale cellular reprogramming at the virus-cell interface
Broich, L.; Wullenkord, H.; Osman, M. K.; Fu, Y.; Reuther, P.; Broenstrup, M.; Sieben, C.
10.1101/2024.07.13.603385 — microbiology — Posted on 2024-07-13
3087 Natural phasic inhibition of dopamine neurons signals cognitive rigidity
Burwell, S. C. V.; Yan, H.; Lim, S. S. X.; Shields, B. C.; TADROSS, M. R.
10.1101/2024.05.09.593320 — neuroscience — Posted on 2024-07-13
3091 E. coli do not count single molecules
Mattingly, H. H.; Kamino, K.; Kottou, R.; Ong, J.; Emonet, T.; Machta, B. B.
10.1101/2024.07.09.602750 — biophysics — Posted on 2024-07-13
3093 Long-term single-molecule tracking in living cells using weak-affinity protein labeling
Catapano, C.; Dietz, M. S.; Kompa, J.; Jang, S.; Freund, P.; Johnsson, K.; Heilemann, M.
10.1101/2024.07.11.603077 — biophysics — Posted on 2024-07-13
3095 A conformational fingerprint for amyloidogenic light chains.
Paissoni, C.; Puri, S.; BROGGINI, L.; Sriramoju, M. K.; Maritan, M.; Russo, R.; Speranzini, V.; Ballabio, F.; Nuvolone, M.; Merlini, G.; Palladini, G.; Hsu, S.-T. D.; Ricagno, S.; Camilloni, C.
10.1101/2024.07.12.603200 — biophysics — Posted on 2024-07-13
3096 Modified Chlorophyll Pigment at ChlD1 Tunes Photosystem II Beyond the Red-Light Limit
Allgower, F.; Sirohiwal, A.; Gamiz-Hernandez, A. P.; Poverlein, M. C.; Fantuzzi, A.; Rutherford, A. W.; Kaila, V. R. I.
10.1101/2024.07.13.603357 — biophysics — Posted on 2024-07-13
3097 DNA supercoiling enhances DNA condensation by ParB proteins
Martin Gonzalez, A.; Tisma, M.; Analikwu, B. T.; Barth, A.; Janissen, R.; Antar, H.; Kemps, G.; Gruber, S.; Dekker, C.
10.1101/2024.07.11.603076 — biophysics — Posted on 2024-07-13
3098 Unveiling the role of yeast cytochrome c isoforms in the assembly of mitochondrial supercomplexes and the control of respiratory chain rate
Guerra-Castellano, A.; Aneas, M.; Tamargo-Azpilicueta, J.; Marquez, I.; Olloqui-Sariego, J. L.; Calvente, J. J.; De la Rosa, M. A.; Diaz Moreno, I.
10.1101/2024.07.13.603375 — biophysics — Posted on 2024-07-13
3099 Rep structures can be tuned by ionicity via metastable intermediates in the absence of DNA
Howard, J. A. L.; Ambrose, B.; Abdelhamid, M. A. S.; Alevropoulos-Borrill, A.; Ejaz, A.; Dresser, L.; Dienerowitz, M.; Quinn, S. D.; Squires, A. H.; Noy, A.; Craggs, T. D.; Leake, M. C.
10.1101/2024.07.12.603287 — biophysics — Posted on 2024-07-13
3100 A novel mechanism of microbial attachment: the flagellar pump of Giardia lamblia
Picou, T. J.; Luo, H.; Polackwich, R.; Gabilondo, B. B.; McAllister, R. G.; Gagnon, D. A.; Powers, T. R.; Elmendorf, H. G.; Urbach, J.
10.1101/2024.07.09.602685 — biophysics — Posted on 2024-07-13
3102 Nitration of a ribosomal pentapeptide generates a noncanonical precursor for nonribosomal peptide synthesis
Padva, L.; Zimmer, L.; Gullick, J.; Zhao, Y.; Sasi, V. M.; Schittenhelm, R. B.; Jackson, C. J.; Cryle, M. J.; Crueseman, M.
10.1101/2024.07.12.603347 — biochemistry — Posted on 2024-07-13
3104 Monovalent Pseudo-Natural Product Degraders Supercharge the Native Degradation of IDO1 by KLHDC3
Hennes, E.; Lucas, B.; Scholes, N. S.; Cheng, X.-f.; Scott, D. C.; Bischoff, M.; Reich, K.; Gasper, R.; Lucas, M.; Xu, T. T.; Pulvermacher, L.-M.; Doetsch, L.; Imrichova, H.; Brause, A.; Naredla, K. R.; Sievers, S.; Kumar, K.; Janning, P.; Gersch, M.; Murray, P. J.; Schulmann, B. A.; Winter, G. E.; Ziegler, S.; Waldmann, H.
10.1101/2024.07.10.602857 — cell biology — Posted on 2024-07-13
3106 Impact of physical activity on physical performance, mitochondrial bioenergetics, ROS production and calcium handling across the human adult lifespan
Cefis, M.; Marcangeli, V.; Hammad, R.; Granet, J.; Leduc-Gaudet, J.-P.; Gaudreau, P.; Trumpff, C.; Huang, Q.; Picard, M.; Aubertin-Leheudre, M.; Belanger, M.; Morais, J. A.; Gouspillou, G.
10.1101/2024.07.09.602758 — cell biology — Posted on 2024-07-13
3109 Maturation of Human Intestinal Epithelial Cell Layers Fortifies the Apical Surface against Salmonella Attack
van Rijn, J. M.; Lopes, A. C. C.; Ceylan, M.; Eriksson, J.; Bergholtz, A.; Ntokaki, A.; Hammar, R.; Sundbom, M.; Skogar, M.; Graf, W.; Webb, D.-L.; Hellström, P. M.; Artursson, P.; Pelaseyed, T.; Di Martino, M. L.; Sellin, M. E.
10.1101/2024.07.11.603014 — cell biology — Posted on 2024-07-13
3110 Cryo-ET reveals the in situ architecture of the polar tube invasion apparatus from microsporidian parasites
Usmani, M.; Coudray, N.; Riggi, M.; Raghu, R.; Ramchandani, H.; Bobe, D.; Kopylov, M.; Zhong, E. D.; Iwasa, J. H.; Ekiert, D. C.; Bhabha, G.
10.1101/2024.07.13.603322 — microbiology — Posted on 2024-07-13
3111 Immunisation of chickens with inactivated and/or infectious H9N2 avian influenza virus leads to differential immune B cell repertoire development
Dascalu, S.; Sealy, J. E.; Sadeyen, J.-R.; Flammer, P. G.; Fiddaman, S.; Preston, S. G.; Dixon, R. J.; Bonsall, M. B.; Smith, A. L.; Iqbal, M.
10.1101/2024.07.09.602583 — immunology — Posted on 2024-07-13
3113 eIF1 and eIF5 dynamically control translation start site fidelity
Grosely, R.; Alvarado, C.; Ivanov, I. P.; Nicholson, O. B.; Puglisi, J. D.; Dever, T. E.; Lapointe, C. P.
10.1101/2024.07.10.602410 — biophysics — Posted on 2024-07-13
3114 Regulation of Kv1.2 redox-sensitive gating by the transmembrane lectin LMAN2
Lamothe, S. M.; Das, D.; Wong, A. A.; Hao, Y.; Maguire, A. D.; Kerr, B. J.; Baronas, V. A.; Kurata, H. T.
10.1101/2024.07.09.602766 — biophysics — Posted on 2024-07-13
3116 Scalable intracellular delivery via microfluidic vortex shedding enhances the function of chimeric antigen receptor T-cells
Sytsma, B. J.; Allain, V.; Bourke, S.; Faizee, F.; Fathi, M.; Berdeaux, R.; Ferreira, L. M. R.; Brewer, J. W.; Li, L.; Pan, F. L.; Rothrock, A. G.; Nyberg, W. A.; Li, Z.; Wilson, L. H.; Eyquem, J.; Pawell, R. S.
10.1101/2024.06.25.600671 — bioengineering — Posted on 2024-07-13
3117 A draft Arab pangenome reference
Nassir, N.; Almarri, M.; Kumail, M.; Mohamed, N.; Balan, B.; Hanif, S.; AlObathani, M.; Jamlalail, B.; Elsokary, H.; Kondaramage, D.; Shiyas, S.; Kosaji, N.; Satsangi, D.; Abdelmotagali, M.; AbouTayoun, A.; Ahmed, O.; Youssef, D.; Al Suwaidi, H.; Albanna, A.; Duplessis, S.; Khansaheb, H.; Alsheikh-Ali, A.; Uddin, M.
10.1101/2024.07.09.602638 — genomics — Posted on 2024-07-13
3119 Moderate Cold Stress Enhance Drought Resistance through CCA1 via -an ABA- independent Pathway
Yang, X.; Liu, Y.; Jia, Z.-C.; Li, M.; Hou, X.-X.; Hou, S.-Q.; Shi, X.-L.; Chen, M.-X.; Liu, Y.-G.
10.1101/2024.07.09.602734 — cell biology — Posted on 2024-07-13
3120 Spleen Tyrosine Kinase (SYK) negatively regulates ITAM-mediated human NK cell signaling and CD19-CAR NK cell efficacy
Millan, A. J.; Allain, V.; Nayak, I.; Aguilar, O. A.; Arakawa- Hoyt, J. S.; Ureno, G.; Rothrock, A. G.; Shemesh, A.; Eyquem, J.; Das, J.; Lanier, L. L.
10.1101/2024.07.09.602676 — immunology — Posted on 2024-07-13
3121 Interleukin-33 from oligodendrocytes sustains effector differentiation of tissue-resident CD8+ T cells and is a druggable target in CNS autoimmune disease
Fonta, N.; Page, N.; Klimek, B.; Piccinno, M.; Di Liberto, G.; Lemeille, S.; Kreutzfeldt, M.; Kastner, A. L.; Ertuna, Y. I.; Vincenti, I.; Wagner, I.; Pinschewer, D. D.; Merkler, D.
10.1101/2024.07.09.602661 — immunology — Posted on 2024-07-13
3122 Flexible neural representations of abstract structural knowledge in the human Entorhinal Cortex
Mark, S.; Baram, A.; Schwartenbeck, P.; Hahamy, A.; Samborska, V.; Behrens, T. E. J.
10.1101/2023.08.31.555760 — neuroscience — Posted on 2024-07-13
3124 A systematic evaluation of dynamic functional connectivity methods using simulation data
Yuan, B.; Yang, J.; Guo, X.; Gao, X.; Hu, Z.; Li, J.; Liu, J.; Wang, Y.; Qu, Z.; Li, W.; Li, Z.; Li, W.; Huang, Y.; Chen, J.; Wen, H.; Li, J.; Liu, D.-Q.; Xie, H.
10.1101/2024.07.09.600728 — neuroscience — Posted on 2024-07-13
3126 Temperature-dependent polar lignification of a seed coat suberin layer promoting dormancy in Arabidopsis thaliana
Hyvärinen, L.; Fuchs, C.; Utz-Pugin, A.; Gully, K.; Megies, C.; Holbein, J.; Iwasaki, M.; Demonsais, L.; Capitao, M. B.; Barberon, M.; Franke, R.; Nawrath, C.; Loubery, S.; Lopez-Molina, L.
10.1101/2024.07.09.602674 — plant biology — Posted on 2024-07-13
3127 Cytokinin acts as a systemic signal coordinating reproductive effort in Arabidopsis
Volkava, D.; Bukovcakova, S. V.; Mikulkova, P.; Pecinkova, J.; Skalak, J.; Hejatko, J.; Riha, K.
10.1101/2024.07.09.602718 — plant biology — Posted on 2024-07-13
3128 HERMES: Holographic Equivariant neuRal network model for Mutational Effect and Stability prediction
Visani, G. M.; Pun, M. N.; Galvin, W.; Daniel, E.; Borisiak, K.; Wagura, U.; Nourmohammad, A.
10.1101/2024.07.09.602403 — bioinformatics — Posted on 2024-07-13
3129 3D Brain Vascular Niche Model Captures Invasive Behavior and Gene Signatures of Glioblastoma
Lee, V. K.; Tejero, R.; Silvia, N.; Sattiraju, A.; Ramakrishnan, A.; Shen, L.; Wojcinski, A.; Kesari, S.; Friedel, R. H.; Zou, H.; Dai, G.
10.1101/2024.07.09.601756 — bioengineering — Posted on 2024-07-13
3131 The regulatory grammar of human promoters uncovered by MPRA-trained deep learning
Barbadilla-Martinez, L.; Klaassen, N. H.; Fransceschini-Santos, V.; Breda, J.; Hernandez-Quiles, M.; van Lieshout, T.; Urzua, C.; Yucel, H.; Boi, M. C. L.; Hermana-Garcia, C.; Gregoricchio, S.; Zwart, W. H.; Voest, E.; Franke, L.; Vermeulen, M.; de Ridder, J.; van Steensel, B.
10.1101/2024.07.09.602649 — genetics — Posted on 2024-07-13
3133 Genetic architecture and adaptation of Ladakh highlanders of trans-Himalayas
Kumar, L.; Rajpal, R.; Ahlawat, B.; Pasupuleti, N.; Konar, S.; Dwivedi, A.; Kumar, S.; Spalzin, S.; Rabyang, S.; Thangaraj, K.; Rai, N.
10.1101/2024.02.05.579041 — genetics — Posted on 2024-07-13
3137 PRC1.6 localizes on chromatin with the human silencing hub (HUSH) complex for promoter-specific silencing
Rodriguez, T. C.; Yurkovetskiy, L.; Nagalekshmi, K.; Lam, C. H. O.; Jazbec, E.; Maitland, S. A.; Wolfe, S.; Sontheimer, E. J.; Luban, J.
10.1101/2024.07.12.603173 — microbiology — Posted on 2024-07-13
3142 Loss of the lysosomal lipid flippase ATP10B leads to progressive dopaminergic neurodegeneration and Parkinsonian motor deficits
Sanchiz-Calvo, M.; Coccia, E.; Cawthorne, C.; Parfitt, G.; Van Laere, K.; Torre-Muruzabal, T.; Cabezudo, D.; Tsafaras, G.; Cascalho, A.; Van Den Haute, C.; Vangheluwe, P.; Blanchard, J.; Bentea, E.; Baekelandt, V.
10.1101/2024.07.09.602700 — neuroscience — Posted on 2024-07-13
3144 Microglia-specific transduction via AAV11 armed with IBA1 promoter and miRNA-9 targeting sequences
Luo, N.; Lin, K.; Cai, Y.; Sui, X.; Zhang, Z.; Xing, J.; Liu, G.; Yuan, W.; Wang, J.; Xu, F.
10.1101/2024.07.09.602653 — neuroscience — Posted on 2024-07-13
3148 Nematode Extracellular Protein Interactome Expands Connections between Signaling Pathways
Nawrocka, W. I.; Cheng, S.; Hao, B.; Rosen, M. C.; Cortes, E.; Baltrusaitis, E. E.; Aziz, Z.; Kovacs, I. A.; Özkan, E.
10.1101/2024.07.08.602367 — biochemistry — Posted on 2024-07-13
3150 Membrane potential as master regulator of cellular mechano-transduction
Mukherjee, A.; Huang, Y.; Elgeti, J.; Oh, S.; Abreu, J.; Neliat, A. R.; Schuttler, J.; Su, D.; Dupre, C.; Benites, N. C.; Liu, X.; Peshkin, L.; Barboiu, M.; Stocker, H.; Kirschner, M. W.; Basan, M.
10.1101/2023.11.02.565386 — cell biology — Posted on 2024-07-13
3151 HIV broadly neutralizing antibody escapability drives the therapeutic efficacy of vectored immunotherapy
Galvez, N. M. S.; Cao, Y.; Nitido, A. D.; Deal, C. E.; Boutros, C. L.; MacDonald, S. W.; Soto Albrecht, Y. E.; Lam, E. C.; Sheehan, M. L.; Parsons, D.; Lin, A. Z.; Deymier, M. J.; Brady, J. M.; Moon, B.; Bullock, C. B.; Tanno, S.; Pegu, A.; Chen, X.; Liu, C.; Koup, R. A.; Mascola, J. R.; Vrbanac, V. D.; Lingwood, D.; Balazs, A. B.
10.1101/2024.07.11.603156 — microbiology — Posted on 2024-07-13
3152 Distinct pathway for evolution of enhanced receptor binding and cell entry in SARS-like bat coronaviruses
Tse, A. L.; Acreman, C. M.; Ricardo-Lax, I.; Berrigan, J.; Lasso, G.; Balogun, T.; Kearns, F. L.; Casalino, L.; McClain, G. L.; Chandran, A. M.; Lemeunier, C.; Amaro, R. E.; Rice, C. M.; Jangra, R. K.; McLellan, J. S.; Chandran, K.; Miller, E. H.
10.1101/2024.06.24.600393 — microbiology — Posted on 2024-07-13
3153 Ventral attention network connectivity is linked to cortical maturation and cognitive ability in childhood
Dong, H.; Zhang, X.-H.; Labache, L.; Zhang, S.; Ooi, L. Q. R.; Yeo, B. T. T.; Margulies, D. S.; Holmes, A.; Zuo, X.-N.
10.1101/2022.04.12.488101 — neuroscience — Posted on 2024-07-13
3157 Transcriptomic analysis of meiotic genes during the mitosis-to-meiosis transition in Drosophila females
Valles, A. M.; Rubin, T.; Macaisne, N.; Dal Toe, L.; Molla-Herman, A.; Antoniewski, C.; Huynh, J.-R.
10.1101/2024.07.10.602987 — developmental biology — Posted on 2024-07-13
3160 Molecular profile, source and lineage restriction of stem cells in an annelid regeneration model
Stockinger, A. W.; Adelmann, L.; Fahrenberger, M.; Ruta, C.; Ozpolat, B. D.; Balavoine, G.; Raible, F.
10.1101/2024.07.09.602635 — developmental biology — Posted on 2024-07-13
3161 Unraveling the immunological roles of serum amyloid A3 in aortic immune cell subsets during atherosclerosis progression
Chou, T.-Y.; Ye, Y.-Z.; Lin, I.-J.; Lien, C.-J.; Yang, C.-H.; Chen, Y.-T.; Chao, P.-A.; Lin, J.-D.
10.1101/2024.07.09.602634 — immunology — Posted on 2024-07-13
3162 The neurovascular coupling response of the aged brain is brain-state dependent.
zhang, X.; Tao, L.; Nygaard, A. H.; Dong, Y.; Hong, X.; Goddard, C. M.; He, C.; Postnov, D. D.; Allodi, I.; Lauritzen, M.; Cai, C.
10.1101/2024.07.09.602636 — neuroscience — Posted on 2024-07-13
3167 Synergistic reinforcement learning by cooperation of the cerebellum and basal ganglia
Yohida, T.; Sugino, H.; Yamamoto, H.; Tanno, S.; Tamura, M.; Igarashi, J.; Isomura, Y.; Hira, R.
10.1101/2024.07.12.603330 — neuroscience — Posted on 2024-07-13
3171 Females with autism spectrum disorders show stronger DNA methylation signatures than males in perinatal tissues
Mouat, J. S.; Krigbaum, N. Y.; Hakam, S.; Thrall, E.; Mellis, J.; Yasui, D. H.; Cirillo, P. M.; Ludena, Y.; Schmidt, R. J.; La Merrill, M. A.; Hertz-Picciotto, I.; Cohn, B. A.; LaSalle, J. M.
10.1101/2024.07.11.603098 — genomics — Posted on 2024-07-13
3172 Glycolytic flux controls retinal progenitor cell differentiation via regulating Wnt signaling
Hanna, J.; Touahri, Y.; Pak, A.; Belfiore, L.; van Oosten, E.; David, L. A.; Han, S.; Ilnytskyy, Y.; Kovalchuk, I.; Kurrasch, D.; Okawa, S.; del Sol, A.; Screaton, R. A.; Aubert, I.; Schuurmans, C.
10.1101/2024.07.12.603298 — developmental biology — Posted on 2024-07-13
3175 CUTS RNA Biosensor for the Real-Time Detection of TDP-43 Loss-of-Function
Xie, L.; Merjane, J.; Bergmann Munoz, C. A.; Xu, J.; Hurtle, B.; Donnelly, C. J.
10.1101/2024.07.12.603231 — molecular biology — Posted on 2024-07-12
3176 The impact of ERUPR on mitochondrial integrity mediated by PDK4
Mallick, P.; Maity, S.; Mondal, R.; Roy, T.; Chakrabarti, O.; Chakrabarti, S.
10.1101/2024.07.12.603217 — molecular biology — Posted on 2024-07-12
3181 NanoTag - an IgG-free method for mapping DNA-protein interactions
Dimitriu, M. A.; Arzate-Mejia, R. G.; Steg, L. C.; Germain, P.-L.; Mansuy, I. M.
10.1101/2024.07.12.603224 — molecular biology — Posted on 2024-07-12
3182 The neonatal Fc receptor and DPP4 are human astrovirus receptors
Ingle, H.; Molleston, J. M.; Hall, P. D.; Bui, D.; Wang, L.; Foster, L.; Antia, A.; Ding, S.; Lee, S.; Fremont, D. H.; Baldridge, M. T.
10.1101/2024.07.12.603331 — microbiology — Posted on 2024-07-12
3183 Previously unknown regulatory role of extracellular RNA on bacterial directional migration
Tetz, V.; Kardava, K.; Vecherkovskaya, M.; Khodadadi-Jamayran, A.; Tsirigos, A.; Tetz, G.
10.1101/2024.07.11.603110 — microbiology — Posted on 2024-07-12
3185 The bat Influenza A virus subtype H18N11 induces nanoscale MHCII clustering upon host cell attachment
Osman, M. K.; Robert, J.; Broich, L.; Frank, D.; Grosse, R.; Schwemmle, M.; Wrobel, A.; Ciminski, K.; Sieben, C.; Reuther, P.
10.1101/2024.07.12.603249 — microbiology — Posted on 2024-07-12
3186 Depletion of skin bacteria by topical antibiotic treatment accelerates onset of Zika virus disease in mice.
Langendries, L.; Verwimp, S.; Jacobs, S.; Alpizar, Y. A.; Malengier-Devlies, B.; Abdelnabi, R.; Raes, J.; Callewaert, C.; Yshii, L.; Delang, L.
10.1101/2024.07.12.602934 — microbiology — Posted on 2024-07-12
3188 MDRepo - an open environment for data warehousing and knowledge discovery from molecular dynamics simulations
Roy, A.; Ward, E.; Choi, I.; Cosi, M.; Edgin, T.; Hughes, T. S.; Islam, M. S.; Khan, A. M.; Kolekar, A.; Rayl, M.; Robinson, I.; Sarando, P.; Skidmore, E.; Swetnam, T. L.; Wall, M.; Xu, Z.; Yung, M. L.; Merchant, N.; Wheeler, T. J.
10.1101/2024.07.11.602903 — biochemistry — Posted on 2024-07-12
3189 The mitochondrial Na+/Ca2+ exchanger NCLX is implied in the activation of hypoxia-inducible factors
Choya-Foces, C.; Hernansanz-Agustin, P.; Navarro, E.; Lopez, M. G.; Egea, J.; Martinez-Ruiz, A.
10.1101/2024.07.12.603081 — biochemistry — Posted on 2024-07-12
3190 The association between metabolite concentrations and wellbeing in adults
Azcona Granada, N.; Geijsen, A. J. M. R.; Pool, R.; Pelt, D. H. M.; Bartels, M.
10.1101/2024.07.12.603238 — biochemistry — Posted on 2024-07-12
3191 Post-proline cleaving enzymes also show specificity to reduced cysteine.
Kalaninova, Z.; Portasikova, J. M.; Jireckova, B.; Polak, M.; Novakova, J.; Kavan, D.; Novak, P.; Man, P.
10.1101/2024.07.12.603020 — biochemistry — Posted on 2024-07-12
3192 Resolving a neonatal intensive care unit outbreak of methicillin-resistant Staphylococcus aureus to the SNV level using Oxford Nanopore simplex reads and HERRO error correction
Bloomfield, M.; Bakker, S.; Burton, M.; Castro, M. L.; Dyet, K.; Eustace, A.; Hutton, S.; Macartney-Coxson, D.; Taylor, W.; White, R. T.
10.1101/2024.07.11.603154 — genomics — Posted on 2024-07-12
3193 DeepOrientation: Deep Orientation Estimation of Macromolecules in Cryo-electron tomography
Hajarolasvadi, N.; Baum, D.; Phelippeau, H.; Martinez-Sanchez, A.; Suau, P.-N.; Brandt, R.
10.1101/2024.07.12.603241 — molecular biology — Posted on 2024-07-12
3195 Cohesin-mediated 3D contacts tune enhancer-promoter regulation
Guckelberger, P.; Doughty, B. R.; Munson, G.; Rao, S. S. P.; Tan, Y.; Cai, X. S.; Fulco, C. P.; Nasser, J.; Mualim, K. S.; Bergman, D. T.; Ray, J.; Jagoda, E.; Munger, C. J.; Gschwind, A. R.; Sheth, M. U.; Tan, A. S.; Steinmetz, L. M.; Lander, E. S.; Meissner, A.; Lieberman Aiden, E.; Engreitz, J. M.
10.1101/2024.07.12.603288 — molecular biology — Posted on 2024-07-12
3199 Seasonal influenza A virus lineages exhibit divergent abilities to antagonize interferon induction and signaling
Rivera-Cardona, J.; Kakuturu, N.; Rowland, E. F.; Teo, Q. W.; Thayer, E. A.; Tan, T. J. C.; Sun, J.; Kieffer, C.; Wu, N. C.; Brooke, C. B.
10.1101/2024.07.11.603146 — microbiology — Posted on 2024-07-12
3200 PRC1.6 localizes on chromatin with the human silencing hub (HUSH) complex for promoter-specific silencing
Rodriguez, T. C.; Yurkovetskiy, L.; Nagalekshmi, K.; Lam, C. H. O.; Jazbec, E.; Maitland, S. A.; Wolfe, S.; Sontheimer, E. J.; Luban, J.
10.1101/2024.07.12.603173 — microbiology — Posted on 2024-07-12
3201 Mechanisms of life cycle simplification in African trypanosomes
Oldrieve, G. R.; Venter, F.; Cayla, M.; Verney, M.; Hebert, L.; Geerts, M.; Van Reet, N.; Matthews, K.
10.1101/2024.07.12.603250 — microbiology — Posted on 2024-07-12
3204 Cryptic cycling by electroactive bacterioplankton in Trout Bog Lake
Olmsted, C. N.; Gahler, M.; Roden, E.; Peterson, B.; Lazarcik, J.; Tran, P. Q.; Berg, M.; Bryant, D. A.; Qin, M.; McMahon, K.
10.1101/2024.07.11.603116 — microbiology — Posted on 2024-07-12
3205 HIV broadly neutralizing antibody escapability drives the therapeutic efficacy of vectored immunotherapy
Balazs, A. B.; Galvez, N. M. S.; Cao, Y.; Nitido, A. D.; Deal, C. E.; Boutros, C. L.; MacDonald, S. W.; Soto Albrecht, Y. E.; Lam, E. C.; Sheehan, M. L.; Parsons, D.; Lin, A. Z.; Deymier, M. J.; Brady, J. M.; Moon, B.; Bullock, C. B.; Tanno, S.; Pegu, A.; Chen, X.; Liu, C.; Koup, R. A.; Mascola, J. R.; Vrbanac, V. D.; Lingwood, D.
10.1101/2024.07.11.603156 — microbiology — Posted on 2024-07-12
3206 Stimulation Effects Mapping for Optimizing Coil Placement for Transcranial Magnetic Stimulation
Zhong, G.; Jin, F.; Ma, L.; Zhang, B.; Cao, D.; Li, J.; Zuo, N.; Fan, L.; Yang, Z.; Jiang, T.
10.1101/2024.02.23.581706 — bioengineering — Posted on 2024-07-12
3209 How much warming can mosquito vectors tolerate?
Couper, L.; Desire Uwera Nalukwago, D.; Lyberger, K.; Farner, J.; Mordecai, E. A.
10.1101/2024.01.03.574109 — ecology — Posted on 2024-07-12
3210 Cmai: Predicting Antigen-Antibody Interactions from Massive Sequencing Data
Song, B.; Wang, K.; Na, S.; Yao, J.; Fattah, F. J.; von Itzstein, M. S.; Yang, D. M.; Liu, J.; Xue, Y.; Liang, C.; Guo, Y.; Raman, I.; Zhu, C.; Dowell, J. E.; Homsi, J.; Rashdan, S.; Yang, S.; Gwin, M. E.; Hsiehchen, D.; Gloria-McCutchen, Y.; Raj, P.; Bai, X.; Wang, J.; Conejo-Garcia, J.; Xie, Y.; Gerber, D. E.; Huang, J.; Wang, T.
10.1101/2024.06.27.601035 — immunology — Posted on 2024-07-12
3211 Multiple mechanisms of aminoglycoside ototoxicity are distinguished by subcellular localization of action
Wu, P.; Becker, F. B.; Ogelman, R.; Camci, E.; Linbo, T. H.; Simon, J. A.; Rubel, E. W.; Raible, D.
10.1101/2024.05.30.596537 — neuroscience — Posted on 2024-07-12
3212 Molecular Connectomics Reveals a Glucagon-Like Peptide 1 Sensitive Neural Circuit for Satiety
Webster, A. N.; Becker, J. J.; Li, C.; Schwalbe, D. C.; Kerspern, D.; Karolczak, E. O.; Bundon, C.; Onoharigho, R. A.; Crook, M.; Jalil, M.; Godschall, E. N.; Dame, E. G.; Dawer, A.; Belmont-Rausch, D. M.; Pers, T. H.; Lutas, A.; Habib, N.; Guler, A. D.; Krashes, M. J.; Campbell, J. N.
10.1101/2023.10.31.564990 — neuroscience — Posted on 2024-07-12
3216 Light-driven synchronization of optogenetic clocks
Cannarsa, M. C.; Liguori, F.; Pellicciotta, N.; Frangipane, G.; Di Leonardo, R.
10.1101/2023.10.24.563722 — synthetic biology — Posted on 2024-07-12
3217 Molecular response to multiple trace-element contamination of the European sardine
Beauvieux, A.; Fromentin, J.-M.; Saraux, C.; Romero, D.; Couffin, N.; Brown, A.; Metral, L.; Bertile, F.; Schull, Q.
10.1101/2024.02.16.580673 — physiology — Posted on 2024-07-12
3218 Identification and quantification of transposable element transcripts using Long-Read RNA-seq in Drosophila germline tissues
Rebollo, R.; Gerenton, P.; Cumunel, E.; Mary, A.; Sabot, F.; Burlet, N.; Gillet, B.; Hughes, S.; Siqueira Oliveira, D.; Goubert, C.; Fablet, M.; Vieira, C.; Lacroix, V.
10.1101/2023.05.27.542554 — bioinformatics — Posted on 2024-07-12
3221 Structural Basis for the Activation of Proteinase-Activated Receptors (PARs) by Endogenous Ligands
Lyu, Z.; Lyu, X.; Xia, G.; Carney, D.; Alves, V. M.; Falk, M.; Arora, N.; Zou, H.; McGrath, A.; Kang, Y.
10.1101/2024.07.08.602624 — biochemistry — Posted on 2024-07-12
3223 Notch induces transcription by stimulating release of paused RNA Pol II without increasing chromatin accessibility
Rogers, J. M.; Mimoso, C. A.; Martin, B. J.; Martin, A. P.; Aster, J. C.; Adelman, K.; Blacklow, S. C.
10.1101/2024.06.13.598853 — genomics — Posted on 2024-07-12
3225 Transcriptional and Cellular Response of hiPSC-derived Microglia-Neural Progenitor Co-Cultures Exposed to IL-6
Couch, A. C. M.; Brown, A.; Raimundo, C.; Solomon, S.; Taylor, M.; Sichlinger, L.; Matuleviciute, R.; Srivastava, D. P.; Vernon, A. C.
10.1101/2023.12.21.572748 — neuroscience — Posted on 2024-07-12
3226 Senolytic therapy preserves blood-brain barrier integrity and promotes microglia homeostasis in a tauopathy model
Yao, M.; Wei, Z.; Nielsen, J. S.; Kakazu, A.; Ouyang, Y.; Li, R.; Chu, T.; Scafidi, S.; Lu, H.; Aggarwal, M.; Duan, W.
10.1101/2024.03.25.586662 — neuroscience — Posted on 2024-07-12
3227 TOR kinase controls Arabidopsis shoot development by translational repression of cytokinin catabolic enzymes
Janocha, D.; Pfeiffer, A.; Dong, Y.; Novak, O.; Strnad, M.; Ryabova, L.; Werner, T.; Lohmann, J. U.
10.1101/2021.07.29.454319 — plant biology — Posted on 2024-07-12
3228 Dual inhibition of ATR and DNA-PKcs radiosensitizes ATM-mutant prostate cancer
Hofstad, M.; Woods, A.; Parra, K.; Sychev, Z. E.; Mazzagatti, A.; Yu, L.; Gilbreath, C.; Ly, P.; Drake, J. M.; Kittler, R.
10.1101/2024.07.10.602941 — cancer biology — Posted on 2024-07-12
3229 Reporter-based screening identifies RAS-RAF stabilizing mutations as drivers of resistance to broad-spectrum RAS inhibition in colorectal cancer
Aust, O.; Blanc, E.; Lüthen, M.; Hollek, V.; Astaburuaga-Garcia, R.; Klinger, B.; Trinks, A.; Beule, D.; Papke, B.; Horst, D.; Bluthgen, N.; Sers, C.; Der, C. J.; Morkel, M.
10.1101/2024.07.01.601542 — cancer biology — Posted on 2024-07-12
3233 Temporally resolved single cell transcriptomics in a human model of amniogenesis
Sekulovski, N.; Carleton, A. E.; Rengarajan, A. A.; Lin, C.-W.; Juga, L. L.; Whorton, A. E.; Kropp Schmidt, J.; Golos, T.; Taniguchi, K.
10.1101/2023.09.07.556553 — developmental biology — Posted on 2024-07-12
3234 A Retinoic Acid:YAP1 signaling axis controls atrial lineage commitment
Abraham, E.; Volmert, B.; Roule, T.; Huang, L.; Yu, J.; Williams, A. E.; Cohen, H. M.; Douglas, A.; Megill, E.; Morris, A.; Stronati, E.; Fueyo, R.; Zubillaga, M.; Elrod, J. W.; Akizu, N.; Aguirre, A.; Estaras, C.
10.1101/2024.07.11.602981 — developmental biology — Posted on 2024-07-12
3235 Mutation of a highly conserved isoleucine residue in loop 2 of several ????-coronavirus macrodomains indicates that enhanced ADP-ribose binding is detrimental to infection
Kerr, C. M.; Pfannenstiel, J. J.; Alhammad, Y. M.; O'Connor, J. J.; Ghimire, R.; Shrestha, R.; Khattabi, R.; Saenjamsai, P.; Parthasarathy, S.; McDonald, P. R.; Gao, P.; Johnson, D. K.; More, S.; Roy, A.; Channappanavar, R.; Fehr, A. R.
10.1101/2024.01.03.574082 — microbiology — Posted on 2024-07-12
3236 Surveillance of H5 HPAI in Michigan using retail milk
Lauring, A. S.; Martin, E. T.; Eisenberg, M. C.; Fitzsimmons, W. J.; Salzman, E.; Leis, A. M.; Lyon-Callo, S.; Bagdasarian, N.
10.1101/2024.07.04.602115 — microbiology — Posted on 2024-07-12
3239 Classification of Parkinson's Disease and Delineating Progression Markers from the Sebum Volatilome
Walton-Doyle, C.; Heim, B.; Sinclair, E.; Lim, S. H.; Hollywood, K.; Milne, J.; Holzknecht, E.; Stefani, A.; Hogl, B.; Seppi, K.; Silverdale, M.; Poewe, W.; Barran, P.; Trivedi, D. K.
10.1101/2023.03.01.530578 — neuroscience — Posted on 2024-07-12
3240 Enhanced purinergic signaling in the paraventricular hypothalamus induces hyperphagic obesity and insulin resistance
Liu, Y.; Zhang, H.; Zhang, Q.; Najam, S. S.; Liang, X.; Sirakawin, C.; Lin, D.; Huang, S.; Bondarenko, A.; Konopka, W.; Zhang, Y.; Zhang, Z.; Wu, S.; Jing, M.; Vinnikov, I. A.
10.1101/2024.07.02.601503 — neuroscience — Posted on 2024-07-12
3241 Targeting cancer with small molecule pan-KRAS degraders
Popow, J.; Farnaby, W.; Gollner, A.; Kofink, C.; Fischer, G.; Wurm, M.; Zollman, D.; Wijaya, A.; Mischerikow, N.; Hasenoehrl, C.; Prokofeva, P.; Arnhof, H.; Arce-Solano, S.; Bell, S.; Boeck, G.; Diers, E.; Frost, A. B.; Goodwin-Tindall, J.; Karolyi-Oezguer, J.; Khan, S.; Klawatsch, T.; Koegl, M.; Kousek, R.; Kratochvil, B.; Kropatsch, K.; Lauber, A. A.; McLennan, R.; Olt, S.; Peter, D.; Petermann, O.; Roessler, V.; Stolt-Bergner, P.; Strack, P.; Strauss, E.; Trainor, N.; Vetma, V.; Whitworth, C.; Zhong, S.; Quant, J.; Weinstabl, H.; Küster, B.; Ettmayer, P.; Ciulli, A.
10.1101/2023.10.24.563163 — pharmacology and toxicology — Posted on 2024-07-12
3243 Unveiling the Structural Proteome of an Alzheimer's Disease Rat Brain Model
Khalili Samani, E.; Hasan, S. M. N.; Waas, M.; Keszei, A. F. A.; Xu, X.; Heydari, M.; Hill, M. E.; McLaurin, J.; Kislinger, T.; Mazhab-Jafari, M. T.
10.1101/2024.07.11.602936 — biochemistry — Posted on 2024-07-12
3245 An MITF- and mTOR-dependent FLCN pathway suppresses TFE3-driven metastasis in melanoma
Chang, J.; Campbell-Hanson, K. R.; Vanneste, M.; Yevdash, J.; Bartschat, N. I.; Jiarui, J.; Bhinu, A.; Helverson, A.; Henry, M.; Steingrimsson, E.; Weigel, R. J.; Cornell, R.; Kenny, C.
10.1101/2024.07.11.603140 — cancer biology — Posted on 2024-07-12
3249 KIF2A maintains cytokinesis in mouse embryonic stem cells by stabilising intercellular bridge microtubules
Stockmann, L.; Kabbech, H.; Kremers, G.-J.; van Herk, B.; Dille, B.; van den Hout, M.; van IJcken, W.; Dekkers, D. H. W.; Demmers, J. A.; Smal, I.; Huylebroeck, D.; Basu, S.; Galjart, N.
10.1101/2024.07.11.603034 — cell biology — Posted on 2024-07-12
3250 An in vivo screen for proteolytic switches that can mediate Notch activation
Jordan, T.; Baker, F.; Harman, J.; Walton, B.; Ajamu-Johnson, A.; Alashqar, R.; Struhl, G.; Langridge, P. D.
10.1101/2024.07.10.602225 — cell biology — Posted on 2024-07-12
3252 TIM-3 blockade enhances ex vivo stimulated allogeneic NK cell therapy for relapsed murine neuroblastoma after hematopoietic cell transplant
Quamine, A.; Mohrdieck, N. R.; King, C. A.; Griggs, A. A.; Kline, J. M.; Cho, M. M.; Rinella, S. P.; Tippins, K. E.; Bates, P. D.; Shi, L.; Song, L.; Hess, N. J.; Kearl, T. J.; Johnson, B. D.; Capitini, C. M.
10.1101/2024.07.09.602731 — immunology — Posted on 2024-07-12
3253 Sarm1-Dependent Metabolic Reprogramming of Schwann Cells Following Nerve Injury
Stepanova, E.; Cho, C.; Lee, J.; Pavelec, C. M.; Tripathi, A.; Vegiraju, T.; Hunter-Chang, S.; Leitinger, N.; Campbell, J. N.; Deppmann, C.
10.1101/2024.07.11.603162 — neuroscience — Posted on 2024-07-12
3258 Nitrate activates a MKK3-dependent MAPK module via NLP transcription factors in Arabidopsis
Schenk, S. T.; Brehaut, V.; Chardin, C.; Boudsocq, M.; Marmagne, A.; Colcombet, J.; Krapp, A.
10.1101/2024.07.09.602786 — plant biology — Posted on 2024-07-12
3260 Coronary Microvascular Dysfunction is Associated with Augmented Lysosomal Signaling in Hypercholesterolemic Mice
Wang, Y.; Moura, A. K.; Zuo, R.; Zhou, W.; Wang, Z.; Roudbari, K.; Hu, J. Z.; Li, P.-L.; Zhang, Y.; Li, X.
10.1101/2024.07.10.603000 — pharmacology and toxicology — Posted on 2024-07-12
3261 Dual inhibition of ATR and DNA-PKcs radiosensitizes ATM-mutant prostate cancer
Hofstad, M.; Woods, A.; Parra, K.; Sychev, Z. E.; Mazzagatti, A.; Yu, L.; Gilbreath, C.; Ly, P.; Drake, J. M.; Kittler, R.
10.1101/2024.07.10.602941 — cancer biology — Posted on 2024-07-12
3264 Fig4 confers tolerance to rapamycin in a Ste20-dependent manner independent of the Vac14 scaffold
Reeves, H. E.; King, A.; Khan, I.; Thomas, A.; Chung, C.; Dotson, L. D.; Sivaprakash, A.; Hall, H. A.; Habib, A.; Lee, S. R.; Lloyd, B. C.; Darbro, C. L.; Strunk, B. S.
10.1101/2024.07.12.603206 — cell biology — Posted on 2024-07-12
3265 L-type calcium channel blockade with verapamil prevents noise induced neuronal dyssynchrony
Yalcinoglu, S.; Braun, R. D.; Wattoo, A.; Apawu, A. K.; Alrayashi, R.; Holt, A. G.
10.1101/2024.07.10.602276 — neuroscience — Posted on 2024-07-12
3266 Oral cannabidiol administration in mice during pregnancy and lactation affects early postnatal body weight, fasting glucose, ingestive behavior, anxiety- and obsessive compulsive-like behaviors, and long-term object-memory in adult offspring in a sex-dependent manner
Krakora Compagno, M.; Silver, C. R.; Cox-Holmes, A.; Basso, K. B.; Bishop, C.; Bernstein, A. M.; Carley, A.; Cazorla, J.; Claydon, J.; Crane, A.; Crespi, C.; Curley, E.; Dolezel, T.; Franck, E.; Heiden, K.; Huffstettler, C. M.; Loeven, A. M.; May, C. A.; Maykut, N.; Narvarez, A.; Pacheco, F. A.; Turner, O.; Fadool, D. A.
10.1101/2024.07.10.602955 — neuroscience — Posted on 2024-07-12
3267 GlyTrait Brings Insights into Functional Glycosylation
Fu, B.; Wang, G.; Li, C.; Li, Y.; Liu, X.; Zhang, Y.; Lu, H.
10.1101/2024.07.09.602632 — bioinformatics — Posted on 2024-07-12
3269 Repeated extrinsic and anisotropic mechanical inputs promote polarized adherens junction elongation
Yang, X.; Ferraro, T.; Molnar, K.; Pontabry, J.; Malanda, S.-R.; Maghelli, N.; Royer, L. A.; Grill, S. W.; Myers, E. W.; Grigolon, S.; Labouesse, M.
10.1101/2024.07.09.602689 — developmental biology — Posted on 2024-07-12
3271 Polycystin-1 loss of function increases susceptibility to atrial fibrillation through impaired DNA damage response
Hendrickson, T.; Abigail Giese, A.; Fiedler, M.; Perez, W.; Reyes-Sanchez, E.; Reyes-Lozano, M.; Wang, S.; Venegas-Zamora, L.; Provasek, V.; El-Essawi, A.; Breitenbach, I.; Fakuade, F. E.; Kutschka, I.; Schiattarella, G. G.; Voigt, N.; Valderrabano, M.; Altamirano, F.
10.1101/2024.07.08.602618 — pathology — Posted on 2024-07-12
3275 Pond Water Microbiome Taxa Profiles and Antibiotic Resistance Genes Associated with Acidity and Tannins
Vaccaro, M.; Pilat, A. M.; Gusmano, L.; Pham, M. T. N.; Barich, D.; Gibson, A.; Epalle, M.; Frost, D. J.; Volin, E.; Slimak, Z. C.; Menke, C. C.; Fennessy, M. S.; Slonczewski, J. L.
10.1101/2024.07.10.602992 — microbiology — Posted on 2024-07-12
3276 Microbial consortia driving lignocellulose transformation in agricultural woodchip bioreactors
Schiml, V.; Walter, J.; Hagen, L. H.; Varnai, A.; Bergaust, L.; de Leon, A. V.-P.; Elsgaard, L.; Bakken, L. R.; Arntzen, M. O.
10.1101/2024.07.11.603112 — microbiology — Posted on 2024-07-12
3277 Malassezia responds to environmental pH signals through the conserved Rim/Pal pathway
Pianalto, K. M.; Telzrow, C. L.; Brown Harding, H.; Brooks, J. T.; Granek, J. A.; Gushiken Ibanez, E.; LeibundGut-Landmann, S.; Heitman, J. B.; Ianiri, G.; Alspaugh, J. A.
10.1101/2024.07.11.603086 — microbiology — Posted on 2024-07-12
3278 Deep learning-driven neuromorphogenesis screenings identify repurposable drugs for mitochondrial disease
Menacho, C.; Okawa, S.; Alvarez-Merz, I.; Wittich, A.; Munoz-Oreja, M.; Lisowski, P.; Pentimalli, T. M.; Rybak-Wolf, A.; Inak, G.; Zakin, S.; Thevandavakkam, M.; Petersilie, L.; Zaliani, A.; Mlody, B.; Seibt, A.; Donnelly, J.; Woleben, K.; Fernandez-Checa, J.; Herebian, D.; Mayatepek, E.; Rajewsky, N.; Spinazzola, A.; Schuelke, M.; Perlstein, E.; Rossi, A.; Distelmaier, F.; Holt, I. J.; Pless, O.; Rose, C.; Del Sol, A.; Prigione, A.
10.1101/2024.07.08.602501 — neuroscience — Posted on 2024-07-12
3279 Extended-depth of field random illumination microscopy, EDF-RIM, provides super-resolved projective imaging
Mazzella, l.; Mangeat, T.; Giroussens, G.; Rogez, B.; Li, H.; Creff, J.; Saadaoui, m.; Martins, C.; Bouzignac, R.; Labouesse, S.; Idier, J.; Galland, F.; Allain, M.; Sentenac, A.; LeGoff, L.
10.1101/2023.10.30.564754 — bioengineering — Posted on 2024-07-12
3280 SMYD5 is a regulator of the mild hypothermia response
Rafnsdottir, S.; Jang, K.; Halldorsdottir, S. T.; Vinod, M.; Tomasdottir, A.; Moller, K.; Halldorsdottir, K.; Reynisdottir, T.; Atladottir, L. H.; Allison, K. E.; Ostacolo, K.; He, J.; Zhang, L.; Northington, F. J.; Magnusdottir, E.; Chavez-Valdez, R.; Anderson, K. J.; Bjornsson, H.
10.1101/2023.05.11.540170 — genetics — Posted on 2024-07-12
3281 KLF6 in Pulmonary Hypertension: The Dual Role of Friend and Foe
Alharbi, R.; Fernandes, N.; Maude, H.; Fellows, A.; Williams, R. D.; Chen, C.-N.; Lambie, N.; Keles, M.; Matthews, N.; Al-Sahaf, M.; Guo, M.; Zhao, L.; Lawrie, A.; Whitsett, J. A.; Cebola, I.; Wojciak-Stothard, B.
10.1101/2024.07.08.602619 — cell biology — Posted on 2024-07-12
3282 Membrane binding properties of the cytoskeletal protein bactofilin
Liu, Y.; Karmakar, R.; Steinchen, W.; Mukherjee, S.; Bange, G.; Schafer, L. V.; Thanbichler, M.
10.1101/2024.06.14.599034 — microbiology — Posted on 2024-07-12
3286 Rabphilin-3A negatively regulates neuropeptide release, through its SNAP25 interaction
Abramian, A.; Hoogstraaten, R. I.; Murphy, F. H.; mcDaniel, K. F.; Toonen, R. F.; Verhage, M.
10.1101/2024.01.05.574432 — neuroscience — Posted on 2024-07-12
3289 ARF1 compartments direct cargo flow via maturation into recycling endosomes
Stockhammer, A.; Adarska, P.; Natalia, V.; Heuhsen, A.; Klemt, A.; Bregu, G.; Harel, S.; Rodilla-Ramirez, C.; Spalt, C.; Oezsoy, E.; Leupold, P.; Grindel, A.; Fox, E.; Mejedo, J. O.; Zehtabian, A.; Ewers, H.; Puchkov, D.; Haucke, V.; Bottanelli, F.
10.1101/2023.10.27.564143 — cell biology — Posted on 2024-07-12
3290 Priming lymphocyte responsiveness and differential T cell signaling in pediatric IBD patients with Cannabis use.
Sanctuary, M. R.; Hudacheck, C. L.; Jones, A. J.; Murphy, B. V.; Welsh, N.; Klawitter, J.; Hoffenberg, E. J.; Collins, C. B.
10.1101/2024.07.08.602495 — immunology — Posted on 2024-07-12
3291 Epidural Spinal Cord Recordings (ESRs): Sources of Artifact in Stimulation Evoked Compound Action Potentials
Deshmukh, A.; Settell, M. L.; Cheng, K. L.; Knudsen, B.; Trevathan, J. K.; LaLuzerne, M.; Blanz, S.; Skubal, A.; Verma, N.; Romanauski, B.; Brucker-Hahn, M.; Lam, D.; Lavrov, I.; Suminski, A.; Weber, D.; Fisher, L.; Lempka, S.; Shoffstall, A.; Park, H.; Ross Ellison, E.; Zhang, M.; Ludwig, K.
10.1101/2024.05.17.594739 — neuroscience — Posted on 2024-07-12
3298 Effects of context changes on memory reactivation
Ozdemir, S.; Senturk, Y. D.; Unver, N.; Demircan, C.; Olivers, C. N. L.; Egner, T.; Gunseli, E.
10.1101/2024.03.20.585920 — neuroscience — Posted on 2024-07-12
3301 Hierarchical structural organization in bioinspired peptide coacervate microdroplets
Lim, J.; Gudlur, S.; Buchanan, C.; Perrin, Q.; Boyd, H.; Moulin, M.; Iwase, H.; Porcar, L.; Cardenas, M.; Miserez, A.; Pervushin, K.
10.1101/2024.07.06.602323 — biochemistry — Posted on 2024-07-12
3303 Nitrogen metabolism in the picoalga Pelagomonas calceolata: disentangling cyanate lyase function under different nutrient conditions.
Guerin, N.; Seyman, C.; Orvain, C.; Bertrand, L.; Gourvil, P.; Probert, I.; Vacherie, B.; Brun, E.; Magdelenat, G.; Labadie, K.; Wincker, P.; Thurotte, A.; Carradec, Q.
10.1101/2024.02.19.580968 — genomics — Posted on 2024-07-12
3304 Comprehensive profiling of transcriptional regulation in cartilage reveals pathogenesis of osteoarthritis
Tian, W.; Dong, S.-S.; Jiang, F.; Zhang, J.-Q.; Wang, C.; He, C.-Y.; Hu, S.-Y.; Hao, R.-H.; Song, H.-M.; Gao, H.-W.; An, K.; Zhu, D.-L.; Yang, Z.; Guo, Y.; Yang, T.-L.
10.1101/2024.06.11.598401 — genetics — Posted on 2024-07-12
3305 On the nature of the earliest known life forms
Kanaparthi, D.; Westall, F.; Lampe, M.; Zhu, B.; Boesen, T.; Klingl, A.; Schwille, P.; Lueders, T.
10.1101/2021.08.16.456462 — evolutionary biology — Posted on 2024-07-12
3306 Drivers of thermal tolerance breadth of plants across contrasting biomes: do mean or seasonality in climate indices matter more?
Briceno, V. F.; Arnold, P. A.; Cook, A. M.; Courtney Jones, S. K.; Gallagher, R. V.; French, K.; Bravo, L. A.; Nicotra, A. B.; Leigh, A.
10.1101/2023.10.02.560437 — ecology — Posted on 2024-07-12
3307 Contraction-induced endocardial id2b plays a dual role in regulating myocardial contractility and valve formation
Chen, S.; Yin, J.; Liang, J.; Zhang, W.; Jiang, P.; Wang, W.; Chen, X.; Zhou, Y.; Xia, P.; Yang, F.; Gu, Y.; Zhang, R.; Han, p.
10.1101/2024.05.09.593293 — developmental biology — Posted on 2024-07-12
3309 Eed controls craniofacial osteoblast differentiation and mesenchymal proliferation from the neural crest
Casey-Clyde, T.; Liu, S. J.; Serrano, J. A. C.; Teng, C.; Jang, Y.-G.; Vasudevan, H. N.; Bush, J. O.; Raleigh, D. R.
10.1101/2024.03.13.584903 — developmental biology — Posted on 2024-07-12
3310 A progeria-associated BAF-1 mutation modulates gene expression and accelerates aging in C. elegans
Romero-Bueno, R.; Fragoso-Luna, A.; Ayuso, C.; Mellmann, N.; Kavsek, A.; Riedel, C. G.; Ward, J. D.; Askjaer, P.
10.1101/2024.03.17.585430 — cell biology — Posted on 2024-07-12
3311 Telomemore enables single-cell analysis of cell cycle and chromatin condensation
Yakovenko, I.; Mihai, I. S.; Selinger, M.; Rosenbaum, W.; Dernstedt, A.; Groning, R.; Trygg, J.; Carroll, L.; Forsell, M.; Henriksson, J.
10.1101/2023.03.19.533267 — immunology — Posted on 2024-07-12
3316 Development of robust antiviral assays using relevant apical-out human airway organoids
Lee, J.-H.; LeCher, J. C.; Parigoris, E.; Shinagawa, N.; Sentosa, J.; Manfredi, C.; Goh, S. L.; De, R.; Tao, S.; Zandi, K.; Amblard, F.; Sorscher, E. J.; Spence, J. R.; Tirouvanziam, R.; Schinazi, R. F.; Takayama, S.
10.1101/2024.01.02.573939 — bioengineering — Posted on 2024-07-12
3321 Noncanonical roles of ATG5 and membrane atg8ylation in retromer assembly and function
Paddar, M. A.; Wang, F.; Trosdal, E.; Hendrix, E.; He, Y.; Salemi, M. R.; Mudd, M.; Jia, J.; Duque, T.; Javed, R.; Phinney, B. S.; Deretic, V.
10.1101/2024.07.10.602886 — cell biology — Posted on 2024-07-12
3322 RABGAP1 acts as a sensor to facilitate sorting and processing of amyloid precursor protein
Eden, J.; Kaufman, J. G. G.; Cattin-Ortola, J.; Benedetti, L.; Nieuwenhuis, B.; Owen, D. J.; Lippincott-Schwartz, J.; Munro, S.; Gershlick, D. C.
10.1101/2024.07.11.602925 — cell biology — Posted on 2024-07-12
3327 The replication principle revisited: a shared functional organization between pulvinar-cortical and cortico-cortical connectivity and its structural and molecular imaging correlates
Basile, G. A.; Ielo, A.; Bonanno, L.; Cerasa, A.; Santoro, G.; Milardi, D.; Anastasi, G. P.; Torre, A.; Baldari, S.; Laudicella, R.; Gaeta, M.; Quartu, M.; Serra, M. P.; Trucas, M.; Quartarone, A.; Saranathan, M.; Cacciola, A.
10.1101/2024.07.11.603063 — neuroscience — Posted on 2024-07-12
3329 A multiomic atlas of human early skeletal development
To, K.; Fei, L.; Pett, J. P.; Roberts, K.; Polanski, K.; Li, T.; Yayon, N.; He, P.; Xu, C.; Cranley, J.; Li, R.; Kanemaru, K.; Huang, N.; Megas, S.; Richardson, L.; Kapuge, R.; Perera, S.; Tuck, E.; Wilbrey-Clark, A.; Mulas, I.; Memi, F.; Cakir, B.; Predeus, A. V.; Horsfall, D.; Murray, S.; Prete, M.; Mazin, P.; He, X.; Meyer, K. B.; Haniffa, M.; Barker, R. A.; Bayraktar, O.; Buckley, C. D.; Teichmann, S. A.
10.1101/2024.07.10.602965 — developmental biology — Posted on 2024-07-12
3330 PRMT1-SFPQ regulates intron retention to control matrix gene expression during craniofacial development
Raulino Lima, J.; Ungvijanpunya, N.; Chen, Q.; Park, G.; Vatankhah, M.; Rosen, T.; Chai, Y.; Merrill, A. E.; Peng, W.; Xu, J.
10.1101/2024.07.09.598733 — developmental biology — Posted on 2024-07-12
3331 A shared threat-anticipation circuit is dynamically engaged at different moments by certain and uncertain threat
Cornwell, B. R.; Didier, P. R.; Grogans, S. E.; Anderson, A. S.; Islam, S.; Kim, H. C.; Kuhn, M.; Tillman, R. M.; Hur, J.; Scott, Z. S.; Fox, A. S.; DeYoung, K. A.; Smith, J. F.; Shackman, A. J.
10.1101/2024.07.10.602972 — neuroscience — Posted on 2024-07-12
3334 The fate of secretory cells during intestinal homeostasis, regeneration, and tumor formation is regulated by Tcf4
Janeckova, L.; Stastna, M.; Hrckulak, D.; Berkova, L.; Kubovciak, J.; Onhajzer, J.; Kriz, V.; Dostalikova, S.; Mullerova, T.; Vecerkova, K.; Tenglerova, M.; Coufal, S.; Kostovcikova, K.; Blumberg, R. S.; Filipp, D.; Basler, K.; Valenta, T.; Kolar, M.; Korinek, V.
10.1101/2024.07.11.603019 — molecular biology — Posted on 2024-07-11
3335 Commensal-pathogen dynamics structure disease outcomes during Clostridioides difficile colonization
Fishbein, S.; DeVeaux, A. L.; Khanna, S.; Ferreiro, A. L.; Liao, J.; Agee, W.; Ning, J.; Mahmud, B.; Wallace, M. J.; Hink, T.; Reske, K. A.; Guruge, J.; Leekha, S.; Dubberke, E. R.; Dantas, G.
10.1101/2024.07.11.603094 — microbiology — Posted on 2024-07-11
3336 The skin microbiome as a new potential biomarker in the domestication and welfare of Octopus vulgaris
Costas-Imbernon, D.; Costas-Prado, C.; Sequeiro, T.; Tourinan, P.; Garcia-Fernandez, P.; Tur, R.; Chavarrias, D.; Saura, M.; Rotllant, J.
10.1101/2024.07.11.602832 — microbiology — Posted on 2024-07-11
3338 Expansion and revision of the genus Xanthobacter and proposal of Roseixanthobacter gen. nov.
Soltysiak, M. P. M.; Jalihal, A. P.; Christophersen, C. E.; Ory, A. L. H.; Lee, A. D.; Boulton, J. M.; Springer, M.
10.1101/2024.07.11.603134 — microbiology — Posted on 2024-07-11
3340 SSR42 is a Novel Regulator of Cytolytic Activity in Staphylococcus aureus
Jobson, M.-E.; Tomlinson, B. R.; Mustor, E. M.; Felton, E. A.; Weiss, A.; Caswell, C. C.; Shaw, L. N.
10.1101/2024.07.11.603084 — microbiology — Posted on 2024-07-11
3341 Using breathing systems in anaesthesia for up to 7 days instead of 24 hours: a comparative microbial safety study
Haanappel, C. P.; Rieff, E. A.; Pavkovic, L.; van Holst-Raaphorst, M. N.; de Groot, W.; van der Marel, C. D.; Voor in 't holt, A. F.; Severin, J. A.
10.1101/2024.07.11.603054 — microbiology — Posted on 2024-07-11
3343 Functionally Validated Proteome-Wide Bioinformatic Annotation of the Monotopic Phosphoglycosyl Transferase Family
Durand, T.; Dodge, G. J.; Siuda, R. P.; Higinbotham, H. R.; Arbour, C. A.; Ghosh, S.; Allen, K. N.; Imperiali, B.
10.1101/2024.07.10.602977 — biochemistry — Posted on 2024-07-11
3345 Direct testing of natural twister ribozymes from over a thousand organisms reveals a broad tolerance for structural imperfections
McKinley, L. N.; Meyer, M. O.; Sebastian, A.; Chang, B. K.; Messina, K. J.; Albert, I.; Bevilacqua, P. C.
10.1101/2024.07.11.603121 — biochemistry — Posted on 2024-07-11
3347 The Fc fragment of soluble IgMs binds C1q to activate the classical complement pathway, while inhibiting complement-dependent cytotoxicity
Pinto, A. J.; Chouquet, A.; Bally, I.; Thielens, N. M.; Dumestre-Perard, C.; Kunert, R.; Gaboriaud, C.; Ling, W. L. W.; REISER, J.-B.
10.1101/2024.07.10.602503 — biochemistry — Posted on 2024-07-11
3349 Systematic characterization of indel variants using a yeast-based protein folding sensor
Larsen-Ledet, S.; Lindemose, S.; Panfilova, A.; Gersing, S.; Suhr, C. H.; Genzor, A. V.; Lanters, H.; Nielsen, S. V.; Lindorff-Larsen, K.; Winther, J. R.; Stein, A.; Hartmann-Petersen, R.
10.1101/2024.07.11.603017 — biochemistry — Posted on 2024-07-11
3350 Metabolic PCTA-Based Shift Reagents for the Selective Detection of Extracellular Lactate Using CEST MRI
Chiaffarelli, R.; Cruz, P.; Zimmermann, M.; Geraldes, C. F. G. C.; Jurek, P.; F. Martins, A.
10.1101/2024.07.09.602789 — biochemistry — Posted on 2024-07-11
3353 Unveiling the Structural Proteome of an Alzheimer's Disease Rat Brain Model
Khalili Samani, E.; Hasan, S. M. N.; Wass, M.; Keszei, A. F. A.; Xu, X.; Heydari, M.; Hill, M. E.; McLaurin, J.; Kislinger, T.; Mazhab-Jafari, M. T.
10.1101/2024.07.11.602936 — biochemistry — Posted on 2024-07-11
3354 Physical interaction with Ephrin B1 promotes CXCR4 intracellular localization and oncogenic potential
Rabbito, A.; Otun, O.; Fumagalli, A.; Seveno, M.; Galant, S.; Counson, M.; Durroux, T.; Bechara, C.; Smit, M. J.; Granier, S.; Szpakowska, M.; Chevigne, A.; Chaumont-Dubel, S.; Marin, P.
10.1101/2024.07.10.602459 — biochemistry — Posted on 2024-07-11
3355 Ketogenesis supports hepatic polyunsaturated fatty acid homeostasis via fatty acid elongation
Queathem, E. D.; Moazzami, Z.; Stagg, D. B.; Nelson, A. B.; Fulghum, K.; Hayir, A.; Seay, A.; Gillingham, J. R.; d`Avignon, D. A.; Han, X.; Ruan, H.-B.; Crawford, P. A.; Puchalska, P.
10.1101/2024.07.09.602593 — biochemistry — Posted on 2024-07-11
3356 Quadrupia: Derivation of G-quadruplexes for organismal genomes across the tree of life
Chantzi, N.; Nayak, A.; Baltoumas, F. A.; Aplakidou, E.; Liew, S. W.; Galuh, J. E.; Patsakis, M.; Moeckel, C.; Mouratidis, I.; Sazed, S. A.; Guiblet, W.; Montgomery, A.; Karmiris-Obratanski, P.; Guliang, W.; Zaravinos, A.; Vasquez, K. M.; Kwok, C. K.; Pavlopoulos, G.; Georgakopoulos-Soares, I.
10.1101/2024.07.09.602008 — genomics — Posted on 2024-07-11
3357 Mitoregulin self-associates to form likely homo-oligomeric pore-like structures
Linzer, C. R.; Stein, C. S.; Witmer, N. H.; Xu, Z.; Schnicker, N. J.; Boudreau, R. L.
10.1101/2024.07.10.601956 — molecular biology — Posted on 2024-07-11
3358 Association study of Plasmodium falciparum Acetyl-CoA Synthetase Mutations S868G and V949I with antimalarial drugs
Zhao, W.; Xiang, Z.; Zeng, W.; Qin, Y.; Pan, M.; Wu, Y.; Duan, M.; Mou, Y.; Liang, T.; Zhang, Y.; Liu, C.; Tang, X.; Huang, Y.; Yang, G.; Cui, L.; Yang, Z.
10.1101/2024.07.10.602966 — microbiology — Posted on 2024-07-11
3360 Human Gastric Multi-Regional Assembloids Favour Functional Parietal Maturation and Allow Modelling of Antral Foveolar Hyperplasia
Jones, B. C.; Benedetti, G.; Cala, G.; Tullie, L.; Simcock, I.; Lutman, R.; Balys, M.; Amiri, R.; Sufi, J.; Arthurs, O.; Eaton, S.; Anderson, G.; Elvassore, N.; Li, V. S.; Jones, K. D.; Tape, C. J.; Luni, C.; Giobbe, G. G.; De Coppi, P.
10.1101/2024.07.08.602480 — cell biology — Posted on 2024-07-11
3361 Global regulation via modulation of ribosome pausing by the ABC-F protein EttA
Ousalem, F.; Ngo, S.; Oiffer, T.; Omairi-Nasser, A.; Monlezun, L.; Boel, G.
10.1101/2023.10.17.562674 — microbiology — Posted on 2024-07-11
3362 Acute rapamycin treatment reveals novel mechanisms of behavioral, physiological, and functional dysfunction in a maternal inflammation mouse model of autism and sensory over-responsivity
Le Belle, J. E.; Condro, M.; Cepeda, C.; Oikonomou, K. D.; Tessema, K.; Dudley, L.; Schoenfield, J.; Kawaguchi, R.; Geschwind, D.; Silva, A. J.; Zhang, Z.; Shokat, K.; Harris, N. G.; Kornblum, H. I.
10.1101/2024.07.08.602602 — neuroscience — Posted on 2024-07-11
3363 VTA μ-opioidergic neurons facilitate low sociability in protracted opioid withdrawal
Jo, A. Y.; Xie, Y.; Rodrigues, A.; Sandoval Ortega, R. A.; Creasy, K. T.; Beier, K. T.; Blendy, J. A.; Corder, G.
10.1101/2024.07.08.602522 — neuroscience — Posted on 2024-07-11
3365 Global genomics of the man-o'-war (Physalia) reveals biodiversity at the ocean surface
Church, S. H.; Abedon, R. B.; Ahuja, N.; Anthony, C. J.; Ramirez, D. A.; Rojas, L. M.; Albinsson, M. E.; Alvarez Trasobares, I.; Bergemann, R. E.; Bogdanovic, O.; Burdick, D. R.; Cunha, T. J.; Damian-Serrano, A.; D'Elia, G.; Dion, K.; Doyle, T. K.; Goncalves, J. M.; Gonzalez Rajal, A.; Haddock, S. H. D.; Helm, R. R.; Le Gouvello, D.; Lewis, Z. R.; Magalhaes, B. I. M. M.; Manko, M. K.; de Mendoza, A.; Moura, C. J.; Nel, R.; Perelman, J. N.; Prieto, L.; Munro, C.; Oguchi, K.; Pitt, K. A.; Schaeffer, A.; Schmidt, A. L.; Sellanes, J.; Wilson, N. G.; Yamamoto, G.; Lazo-Wasem, E.; Simon, C.; Decker,
10.1101/2024.07.10.602499 — zoology — Posted on 2024-07-11
3368 Single-cell analysis of pediatric acute myeloid leukemia samples uncovers treatment-resistant stem and mast cells
Ohlstrom, D.; Bakhtia, M.; Mumme, H.; Michaud, M.; Chien, F.; Pilcher, W.; Satpathy, S.; Jordan, S.; Bhasin, S.; Bhasin, M.
10.1101/2024.07.09.602801 — cancer biology — Posted on 2024-07-11
3373 The impact of Library Size and Scale of Testing on Virtual Screening
Liu, F.; Mailhot, O.; Glenn, I. S.; Vigneron, S. F.; Bassim, V.; Xu, X.; Valencia, K. F.; Smith, M. S.; Radchenko, D. S.; Fraser, J. S.; Moroz, Y. S.; Irwin, J. J.; Shoichet, B. K.
10.1101/2024.07.08.602536 — biophysics — Posted on 2024-07-11
3377 AI-driven high-throughput droplet screening of cell-free gene expression
Zhu, J.; Meng, Y.; Gao, W.; Yang, S.; Zhu, W.; Ji, X.; Zhai, X.; Liu, W.; Luo, Y.; Ling, S.; Li, J.; Liu, Y.
10.1101/2024.07.04.602084 — bioengineering — Posted on 2024-07-11
3379 Body size and light environment modulate flight speed and saccadic behavior in free flying Drosophila melanogaster
Barredo, E.; Yang, H.; Currea, J. P.; Sondhi, Y.; Palavalli-Nettimi, R.; Sponberg, S.; Tarokh, V.; Theobald, J.
10.1101/2024.07.08.602594 — animal behavior and cognition — Posted on 2024-07-11
3381 Dynamic alterations in gene co-expression networks and gene-transcript associations characterize co-morbidities in cocaine use disorder
Nwaneshiudu, C.; Girdhar, K.; Kleopoulos, S.; Fullard, J.; Butelman, E.; Parvaz, M.; Goldstein, R. Z.; Alia-Klein, N.; Roussos, P.
10.1101/2024.07.10.602908 — genomics — Posted on 2024-07-11
3382 Smooth muscle expression of RNA editing enzyme ADAR1 controls vascular integrity and progression of atherosclerosis
Weldy, C. S.; Li, Q.; Monteiro, J. P.; Guo, H.; Galls, D.; Gu, W.; Cheng, P. P.; Ramste, M.; Li, D. Y.; Palmisano, B. T.; Sharma, D.; Worssam, M. D.; Zhao, Q.; Bhate, A.; Kundu, R.; Nguyen, T.; Li, J. B.; Quertermous, T.
10.1101/2024.07.08.602569 — genomics — Posted on 2024-07-11
3383 Optically Mapped Black Genomes: Distinct Structures and 22q11.2 Deletion Syndrome Mechanisms
Pastor, S.; Tran, O.; Lapointe, R.; Olali, A. Z.; Wallace, D. C.; Morrow, B. E.; Zackai, E. H.; McDonald-McGinn, D. M.; Emanuel, B. S.
10.1101/2024.07.08.602568 — genomics — Posted on 2024-07-11
3384 Vcam1+ Fibro-adipogenic Progenitors Mark Fatty Infiltration in Chronic Limb Threatening Ischemia
Dai, Q.; Wan, C.; Xu, Y.; Fei, K.; Olivere, L. A.; Garrett, B.; Akers, L.; Peters, D.; Otto, J. C.; Kontos, C. D.; Ji, Z.; Diao, Y.; Southerland, K. W.
10.1101/2024.07.08.602430 — genomics — Posted on 2024-07-11
3385 Gut metagenomes of Asian octogenarians reveal metabolic potential expansion and distinct microbial species associated with aging phenotypes
Ravikrishnan, A.; Wijaya, I.; Png, E.; Chng, K. R.; Xin Pei, E. H.; Ng, H. Q. A.; Mohamed Naim, A. N.; Eric Emmanuel, J.-S.; Guan, S. P.; Lee, H. J.; Guan, L.; Li, C.; Koh, J. J. Y.; de Sessions, P. F.; Koh, W.-P.; Lei, F.; Ng, T. P.; Larbi, A.; Maier, A. B.; Kennedy, B.; Nagarajan, N.
10.1101/2024.07.08.602612 — genomics — Posted on 2024-07-11
3387 Host-use Drives Convergent Evolution in Clownfish and Disentangles the Mystery of an Iconic Adaptive Radiation
Gaboriau, T. N.; Marcionetti, A.; Garcia Jimenez, A.; Schmid, S.; Fitzgerald, L. M.; Micheli, B.; Titus, B.; Salamin, N.
10.1101/2024.07.08.602550 — evolutionary biology — Posted on 2024-07-11
3390 Global thermal tolerance of freshwater invertebrates and fish
Bayat, H. S.; He, F.; Madariaga, G. M.; Escobar-Sierra, C.; Prati, S.; Jupke, J. F.; Peters, K.; Chen, X.; Spaak, J. W.; Manfrin, A.; Juvigny-Khenafou, N. P. D.; Schäfer, R. B.
10.1101/2024.07.08.602306 — ecology — Posted on 2024-07-11
3391 Entangled and non-modular enhancer sequences producing independent spatial activities
Gompel, N.; Museridze, M.; Ceolin, S.; Muehling, B.; Ramanathan, S.; Barmina, O.; Santhi Sekhar, P.
10.1101/2024.07.08.602541 — developmental biology — Posted on 2024-07-11
3392 Mechanosensitive PIEZO2 channels shape coronary artery development
Pampols-Perez, M.; Fuerst, C.; Sanchez-Carranza, O.; Cano, E.; Raimundo, S.; Lindberg, E. L.; Taube, M.; Heuser, A.; Sporbert, A.; Huebner, N.; Gerhardt, H.; Lewin, G. R.; Hammes, A.
10.1101/2024.07.08.602502 — developmental biology — Posted on 2024-07-11
3395 FLASH proton reirradiation, with or without hypofractionation, mitigates chronic toxicity in the normal murine intestine, skin, and bone.
Verginadis, I. I.; Velalopoulou, A.; Kim, M. M.; Kim, K.; Paraskevaidis, I.; Bell, B.; Oliaei Motlagh, S. A.; Karaj, A.; Banerjee, E.; Finesso, G. E.; Assenmacher, C.-A.; Radaelli, E.; Lu, J.; Lin, Y.; Putt, M. E.; Diffenderfer, E. S.; Guha, C.; Qin, L.; Metz, J. M.; Maity, A.; Cengel, K. A.; Koumenis, C.; Busch, T. M.
10.1101/2024.07.08.602528 — cell biology — Posted on 2024-07-11
3396 The nuclear periphery confers repression on H3K9me2-marked genes and transposons to shape cell fate
Marin, H.; Simental, E.; Allen, C.; Martin, E.; Panning, B.; Al-Sady, B.; Buchwalter, A.
10.1101/2024.07.08.602542 — cell biology — Posted on 2024-07-11
3397 Mitochondrial Fatty Acid Synthesis and Mecr Regulate CD4+ T Cell Function and Oxidative Metabolism
Steiner, K. K.; Young, A. C.; Patterson, A. R.; Jennings, E. Q.; Chi, C.; Hatem, Z.; Heintzman, D.; Sugiura, A.; Arner, E. N.; Sewell, A. E.; Madden, M. Z.; Okparaugo, R.; Fallman, E. V.; Gibson-Corley, K.; Voss, K.; Mogilenko, D.; Rathmell, J.
10.1101/2024.07.08.602554 — immunology — Posted on 2024-07-11
3398 A variational deep-learning approach to modeling memory T cell dynamics
van Dorp, C. H.; Gray, J. I.; Paik, D. H.; Farber, D. L.; Yates, A. J.
10.1101/2024.07.08.602409 — immunology — Posted on 2024-07-11
3399 Structural Mapping of Polyclonal IgG Responses to HA After Influenza Virus Vaccination or Infection
Leon, A. N.; Rodriguez, A. J.; Richey, S. T.; Torrents de la Pena, A.; Wolters, R. M.; Jackson, A. M.; Webb, K.; Creech, C. B.; Yoder, S.; Mudd, P. A.; Crowe, J. E.; Han, J.; Ward, A. B.
10.1101/2024.07.08.601940 — immunology — Posted on 2024-07-11
3401 On the replicability of diffusion weighted MRI-based brain-behavior models
Kotikalapudi, R.; Kincses, B.; Gallitto, G.; Englert, R.; Hoffschlag, K.; Li, J.; Bingel, U.; Spisak, T.
10.1101/2024.07.08.602202 — neuroscience — Posted on 2024-07-11
3406 Newly discovered base barrier cells provide compartmentalization of choroid plexus, brain and CSF
Verhaege, D.; De Nolf, C.; Castelein, J.; Claeys, W.; Van Wonterghem, E.; Van Imschoot, G.; Dujardin, P.; De Spiegelaere, W.; Hoste, E.; Boone, F.; Lidov, H. G.; Dani, N.; Derk, J.; Kremer, A.; Van Hamme, E.; Borghgraef, P.; Lippens, S.; Lehtinen, M. K.; Siegenthaler, J.; Van Hoecke, L.; Vandenbroucke, R. E.
10.1101/2024.07.08.601696 — neuroscience — Posted on 2024-07-11
3407 Spectral-switching analysis reveals real-time neuronal network representations of concurrent spontaneous naturalistic behaviors in human brain
Zhu, H.; Michalak, A. J.; Merricks, E. M.; Agopyan-Miu, A. H. C. W.; Jacobs, J.; Hamberger, M. J.; Sheth, S.; McKhann, G. M.; Feldstein, N.; Schevon, C.; Hillman, E. M. C.
10.1101/2024.07.08.600416 — neuroscience — Posted on 2024-07-11
3408 Mineral Phase Changes During Intervertebral Disc Degeneration
Yenen, T. B.; Jugdaohsingh, R.; Thom, W. D.; Khan, S.; Solano, V. R.; Lampronti, G. I.; Brown, A.; Saez, J.; Corbetta, D.; Eminaga, S.; Cherubini, G. B.; Powell, J.; Hughes, K.; Freeman, P.
10.1101/2024.07.08.602462 — neuroscience — Posted on 2024-07-11
3409 Detrimental Influence of Arginase-1 in Infiltrating Macrophages on Post-Stroke Functional Recovery and Inflammatory Milieu
Kim, H. S.; Jee, S. A.; Einisadr, A.; Seo, Y.; Seo, H. G.; Jang, B. S.; Park, H. H.; Chung, W.-S.; Kim, B. G.
10.1101/2024.07.08.602449 — neuroscience — Posted on 2024-07-11
3411 Translating human drug use patterns into rat models: exploring spontaneous interindividual differences via refined drug self-administration procedures
D'Ottavio, G.; Pezza, S.; Modoni, J.; Reverte, I.; Marchetti, C.; Zenoni, S. F.; Termine, A.; Fabrizio, C.; Maftei, D.; Lattanzi, R.; Esposito, G.; Ragozzino, D.; Merlo, E.; Milella, M. S.; Ciccocioppo, R.; Fumagalli, F.; Venniro, M.; Badiani, A.; Boix, F.; Caprioli, D.
10.1101/2024.07.08.602268 — neuroscience — Posted on 2024-07-11
3412 High-speed three-dimensional random access scanning with SPARCLS
Berlage, C.; Bohm, U. L.; Sanchez Moreno, A.; Ledderose, J.; Gidon, A.; Larkum, M. E.; Plested, A.; Judkewitz, B.
10.1101/2024.07.08.602445 — neuroscience — Posted on 2024-07-11
3413 Interoceptive Signals Bias Decision Making in Rhesus Macaques
Cardenas, M. A.; Le, R. P.; Champ, T. M.; O'Neill, D.; Fuglevand, A. J.; Gothard, K. M.
10.1101/2024.07.08.602563 — neuroscience — Posted on 2024-07-11
3414 Cell-Type-Specific Regulation of Cocaine Reward by the E2F3a Transcription Factor in Nucleus Accumbens
Martinez-Rivera, F. J.; Yim, Y. Y.; Godino, A.; Minier-Toribio, A.; Tofani, S.; Holt, L. M.; Torres-Berrio, A.; Futamura, R.; Browne, C. J.; Markovic, T.; Hamilton, P. J.; Neve, R. L.; Nestler, E. J.
10.1101/2024.07.08.602609 — neuroscience — Posted on 2024-07-11
3415 A multi-region recurrent circuit for evidence accumulation in rats
Gupta, D.; Kopec, C. D.; Bondy, A. G.; Luo, T. Z.; Elliott, V. A.; Brody, C. D.
10.1101/2024.07.08.602544 — neuroscience — Posted on 2024-07-11
3417 Selective deletion of interleukin-1 alpha in microglia does not modify acute outcome but regulates neurorepair processes after experimental ischemic stroke.
Lemarchand, E.; Grayston, A.; Wong, R.; Rogers, M.; Ouvrier, B.; Llewellyn, B.; Webb, F.; Lenart, N.; Denes, A.; Brough, D.; Allan, S. M.; Bix, G.; Pinteaux, E.
10.1101/2024.02.16.580635 — neuroscience — Posted on 2024-07-11
3418 Aberrant remodelling of astrocytic architecture in acute hepatic encephalopathy: complexity of oedematic atrophic astrocytes
Popek, M. P.; Obara-Michlewska, M.; Szewczyk, L. M.; Kolodziej, M.; Verkhratsky, A.; Albrecht, J.; Zielinska, M.
10.1101/2024.07.08.602491 — neuroscience — Posted on 2024-07-11
3421 Multifunctional polymerization domains determine the onset of epigenetic silencing in Arabidopsis
Schulten, A.; Jang, G.-J.; Payne-Dwyer, A.; Nielsen, M. L.; Bienz, M.; Leake, M. C.; Dean, C.
10.1101/2024.02.15.580496 — plant biology — Posted on 2024-07-11
3422 Peripheral Skeletal Muscle Alterations in Adults Born Preterm: An Observational Comparative Study
Deprez, A.; El-Jalbout, R.; Cloutier, A.; Gagnon, D.; Gagnon Hamelin, A.; Mathieu, M.-E.; Arabi Kugathasan, T.; Dumont, N.; Nuyt, A. M.; Luu, T. M.
10.1101/2024.07.08.602584 — physiology — Posted on 2024-07-11
3425 Predicting immunotherapy response in advanced bladder cancer: a meta-analysis of six independent cohorts
Boll, L. M.; Vazquez Montes de Oca, S.; Camarena, M. E.; Castelo, R.; Bellmunt, J.; Perera-Bel, J.; Alba, M. M.
10.1101/2024.04.18.589711 — cancer biology — Posted on 2024-07-11
3433 Healthy microbiome - moving towards functional interpretation
Zielinska, K.; Udekwu, K.; Rudnicki, W.; Frolova, A.; Labaj, P. P.
10.1101/2023.12.04.569909 — bioinformatics — Posted on 2024-07-11
3435 Addressing the dynamic nature of reference data: a new nt database for robust metagenomic classification
Marti, J. M.; Kok, C. R.; Thissen, J. B.; Mulakken, N. J.; Avila-Herrera, A.; Jaing, C. J.; Allen, J. E.; Be, N. A.
10.1101/2024.06.12.598617 — bioinformatics — Posted on 2024-07-11
3440 Loss of cped1 does not affect bone and lean mass in zebrafish
Alvarado, K.; Tang, W. J.; Watson, C. J.; Ahmed, A. R.; Gomez, A. E.; Donaka, R.; Amemiya, C. T.; Karasik, D.; Hsu, Y.-H.; Kwon, R. Y.
10.1101/2024.07.10.601974 — genetics — Posted on 2024-07-11
3441 Piwi mutant germ cells transmit a form of heritable stress that promotes longevity
Heestand, B.; McCarthy, B.; Simon, M.; Lister-Shimauchi, E. H.; Frenk, S.; Ahmed, S.
10.1101/326769 — genetics — Posted on 2024-07-11
3443 The evolutionary history of the ancient weevil family Belidae (Coleoptera: Curculionoidea) reveals the marks of Gondwana breakup and major floristic turnovers, including the rise of angiosperms
Li, X.; Marvaldi, A. E.; Oberprieler, R. G.; Clarke, D.; Farrell, B. D.; Sequeira, A.; Ferrer, M. S.; O'Brien, C.; Salzman, S.; Shin, S.; Tang, W.; McKenna, D. D.
10.1101/2024.03.12.584611 — evolutionary biology — Posted on 2024-07-11
3447 Population density drives increased parasitism via greater exposure and reduced resource availability in wild hosts
Hasik, A. Z.; Butt, S.; Turner, R. S.; Maris, K.; Morris, S.; Morris, A.; Pemberton, J. M.; Albery, G. F.
10.1101/2024.07.08.602460 — ecology — Posted on 2024-07-11
3450 Single cell profiling to determine influence of wheeze and early-life viral infection on developmental programming of airway epithelium
Berdnikovs, S.; Newcomb, D. C.; McKernan, K. E.; Kuehnle, S. N.; Haruna, N.-F.; Gebretsadik, T.; McKennan, C. G.; Ma, S.; Cephus, J.-Y.; Rosas-Salazar, C.; Anderson, L. J.; Gern, J. E.; Hartert, T.
10.1101/2024.07.08.602506 — developmental biology — Posted on 2024-07-11
3451 Endogenous FGFs drive ERK-dependent cell fate patterning in 2D human gastruloids
Jo, K.; Liu, Z.-Y.; Patel, G.; Yu, Z.; Yao, L.; Teague, S.; Johnson, C.; Spence, J.; Heemskerk, I.
10.1101/2024.07.08.602611 — developmental biology — Posted on 2024-07-11
3453 Facultative endosymbiosis between cellulolytic protists and methanogenic archaea in the gut of the Formosan termite Coptotermes formosanus
Kaneko, M.; Omori, T.; Igai, K.; Mabuchi, T.; Sakai-Tazawa, M.; Nishihara, A.; Kihara, K.; Yoshimura, T.; Ohkuma, M.; Hongoh, Y.
10.1101/2024.05.03.592298 — microbiology — Posted on 2024-07-11
3454 A comprehensive two-hybrid analysis to explore the L. pneumophila effector-effector interactome
O'Connor Mount, H.; Urbanus, M. L.; Sheykhkarimli, D.; Cote, A. G.; Laval, F.; Coppin, G.; Kishore, N.; Li, R.; Spirohn-Fitzgerald, K.; Petersen, M. O.; Knapp, J. J.; Kim, D.-K.; Twizere, J.-C.; Calderwood, M. A.; Vidal, M.; Roth, F. P.; Ensminger, A. W.
10.1101/2024.03.29.587239 — microbiology — Posted on 2024-07-11
3455 Membrane binding properties of the cytoskeletal protein bactofilin
Liu, Y.; Karmakar, R.; Steinchen, W.; Mukherjee, S.; Bange, G.; Schafer, L. V.; Thanbichler, M.
10.1101/2024.06.14.599034 — microbiology — Posted on 2024-07-11
3456 Sleep and memory consolidation are linked by RNA processing genes in the Drosophila mushroom body
Li, Y.; Chouhan, N. S.; Zhang, S. L.; Moore, R. S.; Shon, J.; Noya, S. B.; Yue, Z.; Sehgal, A.
10.1101/2023.05.31.543136 — neuroscience — Posted on 2024-07-11
3461 A Myelin Map of Trunk Folds in the Elephant Trigeminal Nucleus
Reveyaz, N.; Schneeweiss, U.; Heise, O.; Gerhardt, B.; Gui, A. M.; Kaufmann, L. V.; Alfken, J.; Reichmann, J.; Salditt, T.; Hildebrandt, T. B.; Brecht, M.
10.1101/2023.11.15.567239 — neuroscience — Posted on 2024-07-11
3462 Automating clinical assessments of memory deficits: Deep Learning based scoring of the Rey-Osterrieth Complex Figure
Langer, N.; Weber, M.; Hebling Vieira, B.; Strzelczyk, D.; Wolf, L.; Pedroni, A.; Heitz, J.; Schultheis, C.; Troendle, M.; Arango Lasprilla, J. C.; Rivera, D.; Scarpina, F.; Zhao, Q.; Leuthold, R.; Wehrle, F.; Jenni, O. G.; Brugger, P.; Zaehle, T.; Lorenz, R.; Zhang, C.
10.1101/2022.06.15.496291 — neuroscience — Posted on 2024-07-11
3464 Neural Prioritisation of Past Solutions Supports Generalisation
Hall-McMaster, S.; Tomov, M. S.; Gershman, S. J.; Schuck, N. W.
10.1101/2024.06.10.598294 — neuroscience — Posted on 2024-07-11
3465 Life Cycle and Morphogenetic Differentiation in Heteromorphic Cell Types of a Cosmopolitan Marine Microalga
Bousquet, L.; Fainsod, S.; Decelle, J.; Murik, O.; Chevalier, F.; Gallet, B.; Templin, R.; Schwab, Y.; Avrahami, Y.; Koplovitz, G.; Ku, C.; Frada, M.
10.1101/2024.07.03.601694 — plant biology — Posted on 2024-07-11
3466 Deep phenotyping of the prostate tumor microenvironment reveals molecular stratifiers of relapse and links inflammatory chemokine expression to aberrant metabolism
Krossa, S.; Andersen, M. K.; Midtbust, E.; Wess, M.; Kiviaho, A.; Sharma, A.; Viset, T.; Storkersen, O.; Giskeodegard, G. F.; Nykter, M.; Urbanucci, A.; Rye, M. B.; Tessem, M.-B.
10.1101/2024.05.13.593822 — cancer biology — Posted on 2024-07-11
3467 Resolving atomic-level dynamics and interactions of high-molecular weight hyaluronic acid by multidimensional solid-state NMR
Rampratap, P.; Lasorsa, A.; Arunachalam, A.; Kamperman, M.; Walvoort, M. T. C.; van der Wel, P. C. A.
10.1101/2024.02.29.582163 — biophysics — Posted on 2024-07-11
3468 Sizes, conformational fluctuations, and SAXS profiles for Intrinsically Disordered Proteins
Mugnai, M. L.; Chakraborty, D.; Kumar, A.; Nguyen, H. T.; Zeno, W.; Stachowiak, J. C.; Straub, J. E.; Thirumalai, D.
10.1101/2023.04.24.538147 — biophysics — Posted on 2024-07-11
3469 Nuclear RNAi Modulates Influenza A Virus Infectivity By Downregulating Type-I Interferon Response
Huang, H.-C.; Nowak, I.; Lobo, V.; Besavilla, D. F.; Schon, K.; Westholm, J. O.; Fernandez, C.; Patel, A. A.; Wiel, C.; Sayin, V. I.; Anastasakis, D. G.; Angeletti, D.; Sarshad, A. A.
10.1101/2024.03.07.583365 — biochemistry — Posted on 2024-07-11
3470 The Open Pediatric Cancer Project
Geng, Z.; Wafula, E.; Corbett, R. J.; Zhang, Y.; Jin, R.; Gaonkar, K. S.; Shukla, S.; Rathi, K. S.; Hill, D.; Lahiri, A.; Miller, D. P.; Sickler, A.; Keith, K.; Blackden, C.; Chroni, A.; Brown, M. A.; Kraya, A. A.; Koschmann, C. J.; Aldape, K.; Huang, X.; Rood, B. R.; Mason, J. L.; Trooskin, G. R.; Abdullaev, Z.; Wang, P.; Zhu, Y.; Farrow, B. K.; Farrel, A.; Dybas, J. M.; Zhong, C.; Van Kuren, N.; Zhang, B.; Santi, M.; Phul, S.; Chinwalla, A. T.; Resnick, A. C.; Diskin, S. J.; Tasian, S.; Stefankiewicz, S.; Maris, J. M.; Ennis, B. M.; Lueder, M. R.; Naqvi, A. S.; Coleman, N.; Ma, W.; Taylor, D
10.1101/2024.07.09.599086 — genomics — Posted on 2024-07-11
3472 Diversification and recurrent adaptation of the synaptonemal complex in Drosophila
Zakerzade, R.; Chang, C.-H.; Chatla, K.; Krishnapura, A.; Appiah, S. P.; Zhang, J.; Unckless, R. L.; Blumenstiel, J.; Bachtrog, D.; Wei, K. H.
10.1101/2023.10.20.563324 — evolutionary biology — Posted on 2024-07-11
3473 Cardiomyocyte antisense transcription regulates exon usage in the elastic spring region of Titin to modulate sarcomere function
Celik, S.; Hyrefelt, L.; Czuba, T.; Li, Y.; Assis, J.; Andre, O.; Sandstedt, J.; Nordenfelt, P.; Vukusic, K.; Smith, J. G.; Gidlof, O.
10.1101/2024.07.10.602998 — molecular biology — Posted on 2024-07-11
3476 Impacts of Antiretroviral Therapy on the Oral Microbiome and Periodontal Health of Feline Immunodeficiency Virus Positive Cats
Bashor, L.; Rawlinson, J. E.; Kozakiewicz, C. P.; Behzadi, E.; Miller, C.; Kim, J.; Conry, M.; Nehring, M.; Carver, S.; Abdo, Z.; VandeWoude, S.
10.1101/2024.07.10.602918 — microbiology — Posted on 2024-07-11
3478 Brief targeting of resurgent STAT3 activation in chronic epilepsy for potent and enduring disease modification.
Hoffman, O. R.; Koehler, J. L.; Espina, J. E. C.; Patterson, A.; Gohar, E.; Coleman, E.; Schoenike, B.; Espinosa-Garcia, C.; Paredes, F.; Dingledine, R.; Maguire, J.; Roopra, A.
10.1101/2023.08.07.552299 — neuroscience — Posted on 2024-07-11
3479 A cancer immunotherapy modality based on dendritic cell reprogramming in vivo
Ascic, E.; Akerstrom, F.; Sreekumar Nair, M.; Rosa, A.; Kurochkin, I.; Zimmermannova, O.; Catena, X.; Rotankova, N.; Veser, C.; Rudnik, M.; Ballocci, T.; Scharer, T.; Huang, X.; de Rosa Torres, M.; Renaud, E.; Velasco Santiago, M.; Met, O.; Askmyr, D.; Lindstedt, M.; Greiff, L.; Ligeon, L.-A.; Agarkova, I.; Svane, I. M.; F. Pires, C.; F. Rosa, F.; Pereira, C.-F.
10.1101/2024.07.08.602356 — immunology — Posted on 2024-07-11
3480 Spatial and mechanical environments regulate the heterogeneity of myonuclei
NICOLAS, R.; BLAVET, c.; BONNIN, M.-A.; ESTEVES DE LIMA, J.; LEGALLAIS, C.; DUPREZ, D.
10.1101/2024.07.08.602510 — developmental biology — Posted on 2024-07-11
3481 FtsN coordinates septal peptidoglycan synthesis and degradation through self-interaction of SPOR in E. coli
Lyu, Z.; Yang, X.; Yahashiri, A.; Ha, S.; McCausland, J. W.; Chen, X.; Britton, B. M.; Weiss, D. S.; Xiao, J.
10.1101/2024.05.13.594014 — microbiology — Posted on 2024-07-11
3486 Biomolecular condensates can function as inherent catalysts
Guo, X.; Farag, M.; Qian, N.; Yu, X.; Ni, A.; Ma, Y.; Yu, W.; King, M.; Liu, V.; Lee, J.; Min, W.; Zare, R. N.; Pappu, R. V.; Dai, Y.
10.1101/2024.07.06.602359 — biophysics — Posted on 2024-07-11
3487 Optimization of an adeno-associated viral vector for epidermal keratinocytes in vitro and in vivo
Shen, Q.; Suga, S.; Moriwaki, Y.; Zening, D.; Aizawa, E.; Okazaki, M.; Izpisua Belmonte, J. C.; Hirabayashi, Y.; Suzuki, K.; Kurita, M.
10.1101/2024.04.15.589645 — bioengineering — Posted on 2024-07-11
3489 Impaired motor-to-sensory transformation mediates auditory hallucinations
Yang, F.; Zhu, H.; Cao, X.; Li, H.; Fang, X.; Yu, L.; Li, S.; Wu, Z.; Li, C.; Zhang, C.; Tian, X.
10.1101/2023.06.10.544451 — neuroscience — Posted on 2024-07-11
3490 GATA6 regulates WNT and BMP programs to pattern precardiac mesoderm during the earliest stages of human cardiogenesis
Bisson, J. A.; Gordillo, M.; Kumar, R.; de Silva, N.; Yang, E.; Banks, K. M.; Shi, Z.-D.; Lee, K.; Yang, D.; Chung, W. K.; Huangfu, D.; Evans, T.
10.1101/2024.07.09.602666 — developmental biology — Posted on 2024-07-11
3491 A high affinity monoclonal antibody against HLA-E-VL9 enhances natural killer cell anti-tumor killing
Hwang, J. K.; Marston, D. J.; Wrapp, D.; Li, D.; Tuyishime, M.; Brackenridge, S.; Rhodes, B.; Quastel, M.; Kapingidza, A. B.; Gater, J.; Harner, A.; Wang, Y.; Rountree, W.; Ferrari, G.; Borrow, P.; McMichael, A. J.; Gillespie, G. M.; Haynes, B. F.; Azoitei, M. L.
10.1101/2024.07.08.602401 — immunology — Posted on 2024-07-11
3492 Local genetic adaptation to habitat in wild chimpanzees
Ostridge, H. J.; Fontsere, C.; Lizano, E.; Soto, D. C.; Schmidt, J. M.; Saxena, V.; Alvarez-Estape, M.; Barratt, C. D.; Gratton, P.; Bocksberger, G.; Lester, J. D.; Dieguez, P.; Agbor, A.; Angedakin, S.; Assumang, A. K.; Bailey, E.; Barubiyo, D.; Bessone, M.; Brazzola, G.; Chancellor, R.; Cohen, H.; Coupland, C.; Danquah, E.; Deschner, T.; Dotras, L.; Dupain, J.; Egbe, V. E.; Granjon, A.-C.; Head, J.; Hedwig, D.; Hermans, V.; Hernandez-Aguilar, R. A.; Jeffery, K. J.; Jones, S.; Junker, J.; Kadam, P.; Kaiser, M.; Kalan, A. K.; Kambere, M.; Kienast, I.; Kujirakwinja, D.; Langergraber, K. E.; Lap
10.1101/2024.07.09.601734 — evolutionary biology — Posted on 2024-07-11
3495 Elucidating Interactome Dynamics of the A2A Adenosine Receptor
Lee, W.; Son, A.; Kim, W.; Park, J.; Cho, J.-y.; Kim, J.-W.; Kim, Y.-O.; Kong, H. J.; Kim, H.
10.1101/2024.07.08.601789 — systems biology — Posted on 2024-07-11
3497 Unveiling Clonal Cell Fate and Differentiation Dynamics: A Hybrid NeuralODE-Gillespie Approach
Gao, M.; Barile, M.; Chabra, S.; Haltalli, M.; Calderbank, E.; Chao, Y.; Laurenti, E.; Gottgens, B.; Huang, Y.
10.1101/2024.07.08.602444 — bioinformatics — Posted on 2024-07-11
3498 Maternal obesity and offspring neurodevelopment are associated with hypoxic gene expression in term human placenta
Gunter-Rahman, F.; Mallett, S.; White, F.; Jacques, P.-E.; Raju, R. M.; Hivert, M.-F.; Lee, E. A.
10.1101/2024.07.10.602900 — genomics — Posted on 2024-07-10
3500 Beyond brain size: disentangling the effect of sex and brain size on brain morphometry and cognitive functioning
Brzezinski-Rittner, A.; Moqadam, R.; Iturria-Medina, Y.; Chakravarty, M.; Dadar, M.; Zeighami, Y.
10.1101/2024.06.20.599908 — neuroscience — Posted on 2024-07-10
3503 Striatal endocannabinoid-long-term potentiation mediates one-shot learning
Piette, C.; Hubert, A.; Perez, S.; Berry, H.; Touboul, J. D.; Venance, L.
10.1101/2024.07.10.602953 — neuroscience — Posted on 2024-07-10
3504 Functional ultrasound imaging and neuronal activity: how accurate is the spatiotemporal match?
Lambert, T.; Niknejad, H. R.; Kil, D.; Brunner, C.; Nuttin, B.; Montaldo, G.; Urban, A.
10.1101/2024.07.10.602912 — neuroscience — Posted on 2024-07-10
3505 Neuronal Hyperactivity in Neurons Derived from Individuals with Grey Matter Heterotopia
Di Matteo, F.; Bonrath, R.; Schmidt, H.; Ayo Martin, A. C.; Pravata, V.; Di Giaimo, R.; Menegaz, D.; Riesenberg, S.; de Vrij, F. M. S.; Maccarrone, G.; Holzapfel, M.; Straub, T.; Kushner, S. A.; Robertson, S. P.; Matthias Eder, M.; Cappello, S.
10.1101/2024.07.10.602948 — neuroscience — Posted on 2024-07-10
3511 Mitochondria-containing extracellular vesicles from mouse vs. human brain endothelial cells for ischemic stroke therapy
Dave, K. M.; Venna, V. R.; Rao, K. S.; Stolz, D. B.; Brady, B.; Quaicoe, V. A.; Maniskas, M.; Hildebrand, E. E.; Green, D.; Chen, M.; Milosevic, J.; Zheng, S.-y.; Shiva, S.; McCullough, L. D.; Manickam, D. S.
10.1101/2024.01.16.575903 — bioengineering — Posted on 2024-07-10
3513 Deletion of an evolutionarily conserved TAD boundary compromises spermatogenesis in mice
Lima, A. C.; Okhovat, M.; Stendahl, A. M.; VanCampen, J.; Nevonen, K. A.; Herrera, J.; Li, W.; Harshman, L.; Yang, R.; Fedorov, L.; Vigh-Conrad, K.; Ahituv, N.; Conrad, D.; Carbone, L.
10.1101/2024.07.08.602428 — genetics — Posted on 2024-07-10
3515 Vestigial like 4 regulates the adipogenesis of classical brown adipose tissue
Zhou, P.; Kessinger, C. W.; Gu, F.; Davenport, A.; Wang, G.; Deplancke, B.; Pu, W. T.; Lin, Z.
10.1101/2024.07.09.602788 — developmental biology — Posted on 2024-07-10
3516 Single Cell Transcriptomics-informed Induced Pluripotent Stem Cells Differentiation to Tenogenic Lineage
Papalamprou, A.; Yu, V.; Jiang, W.; Sheyn, J.; Stefanovic, T.; Chen, A.; Castaneda, C.; Chavez, M.; Sheyn, D.
10.1101/2023.04.10.536240 — developmental biology — Posted on 2024-07-10
3517 Newborn reactions to maternal prenatal stress alter umbilical cord blood tRNA fragments targeting cholinergic transcripts
Vaknine Treidel, S.; Lobmaier, S.; Sharma, R.; Madrer, N.; Shulman, D.; Greenberg, P.; Bennett, E. R.; Greenberg, D. S.; Zelgert, C.; Zimmermann, P.; Frasch, M. G.; Carmel, L.; Antonelli, M. C.; Soreq, H.
10.1101/2024.07.10.602894 — molecular biology — Posted on 2024-07-10
3521 QuickFit: A high-throughput RT-qPCR-based assay to quantify viral growth and fitness in vitro
Galvez, N. M. S.; Sheehan, M. L.; Lin, A. Z.; Cao, Y.; Lam, E. C.; Jackson, A. M.; Balazs, A. B.
10.1101/2024.07.08.602587 — microbiology — Posted on 2024-07-10
3522 A functional interleukin-4 homolog is encoded in the genome of infectious laryngotracheitis virus: unveiling a novel virulence factor
Volkening, J. D.; Spatz, S. J.; Garcia, M.; Zamora, A. C.; Rosenthal, K. S.; Skipper, A.; Blakey, J.; Ross, T. A.
10.1101/2024.07.10.602945 — microbiology — Posted on 2024-07-10
3525 Dynamics of bacterial biofilm development imaged using light sheet fluorescence microscopy
Smerdova, L.; Fuzik, T.; Valentova, L.; Bardy, P.; Prochazkova, M.; Parenicova, M.; Plevka, P.
10.1101/2024.07.10.602771 — microbiology — Posted on 2024-07-10
3526 Environmental differences impact Acinetobacter baumannii phage isolation and infectivity
Alseth, E. O.; Roush, C.; Irby, I.; Kopylov, M.; Bobe, D.; Nguyen, K.; Xu, H.; Bryksin, A. V.; Rather, P. N.
10.1101/2024.07.10.602838 — microbiology — Posted on 2024-07-10
3527 Engineering programmable CAR-T cells with tunable controls as fail-safe mechanisms during cancer immunotherapy
Dogan, M.; Kozhaya, L.; Placek, L.; Karhan, E.; Yigit, M.; Mohammed, C.; Zhao, Q.; Unutmaz, D.
10.1101/2024.07.09.602762 — immunology — Posted on 2024-07-10
3530 NMR Reveals the Synergistic Roles of Bivalent Metal Ions in Norovirus Infections
Maass, T.; Westermann, L. T.; Sharotri, L.; Blankenhorn, L.; Lane, M. S.; Chaika, M.; Taube, S.; Peters, T.; Mallagaray, A.
10.1101/2024.07.10.602906 — biochemistry — Posted on 2024-07-10
3532 Modulating immune cell fate and inflammation through CRISPR-mediated DNA methylation editing
Valcarcel, G.; Lopez-Rubio, A. V.; Lazarenkov, A.; Berenguer, C.; Calafell, J.; Rodriguez-Ubreva, J.; Ballestar, E.; Sardina, J. L.
10.1101/2024.07.10.599183 — genomics — Posted on 2024-07-10
3535 Importin alpha inhibitors act against the differentiated stages of apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii
Bhambid, M.; Walunj, S. B.; C.A., A.; Jain, S.; Mehta, D.; Wagstaff, K.; Panda, A.; Jans, D.; Mohmmed, A.; Patankar, S.
10.1101/2024.07.10.602875 — molecular biology — Posted on 2024-07-10
3536 A unique mechanism of snRNP core assembly
Wang, Y.; Chen, X.; Kong, X.; Chen, Y.; Xiang, Z.; Xiang, Y.; Hu, Y.; Hou, Y.; Zhou, S.; Shen, C.; Mu, L.; Su, D.; Zhang, R.
10.1101/2024.07.09.602679 — molecular biology — Posted on 2024-07-10
3537 A Transfection-Free Approach of Gene Editing via a gold-based nanoformulation of the Cas9 protein
Konstantinidou, S.; Lindstaedt, A.; Schmidt, T. J. N.; Nocilla, F.; Maltinti, G.; Rocco, M. A.; Landi, E.; De Carli, A.; Crucitta, S.; Lai, M.; Pistello, M.; Cappello, V.; Witt, D.; Gabellini, C.; Barski, P.; Raffa, V.
10.1101/2024.07.09.602746 — molecular biology — Posted on 2024-07-10
3538 Inhibitor-induced supercharging of kinase turnover via endogenous proteolytic circuits
Scholes, N. S.; Bertoni, M.; Comajuncosa-Creus, A.; Kladnik, K.; Frommelt, F.; Hinterndorfer, M.; Razumkov, H.; Prokofeva, P.; Schwalm, M. P.; Imrichova, H.; Barone, E.; Schätz, C.; Rukavina, A.; Koren, A.; Kubicek, S.; Knapp, S.; Gray, N. S.; Superti-Furga, G.; Küster, B.; Aloy, P.; Winter, G. E.
10.1101/2024.07.10.602881 — molecular biology — Posted on 2024-07-10
3541 Star-polymers as potent broad-spectrum extracellular virucidal antivirals
Super, E. H.; Lai, S. M.; Cytlak-Chaudhuri, U.; Coppola, F.; Saouaf, O. M.; Song, Y. E.; Casey, K. M.; Batt, L. J.; Macleod, S.-L.; Bagley, R. H. T.; Korb, Z.; Kral, P.; Appel, E.; Travis, M.; Jones, S. T.
10.1101/2024.07.10.602907 — microbiology — Posted on 2024-07-10
3543 N-acylethanolamine acid amidase inhibition reduces SARS-CoV-2 infection in Human Precision cut-lung slices and downregulates NF-kappaB signalling.
La Rocca, V.; Filipponi, C.; Diesendorf, V.; De Carli, A.; Sciandrone, G.; Nottoli, S.; Plicanti, E.; Fonnesu, R.; Iacono, E.; Mengozzi, A.; Masi, S.; Lenzi, P.; Fornai, F.; Sewald, K.; Obernolte, H.; Bodem, J.; Freer, G.; Pistello, M.; Lai, M.
10.1101/2024.07.10.602842 — microbiology — Posted on 2024-07-10
3545 Omicron-specific ultra-potent SARS-CoV-2 neutralizing antibodies targeting the N1/N2 loop of Spike N-terminal domain
Niu, X.; Li, Z.; Wang, J.; Jian, F.; Yu, Y.; Song, W.; Yisimayi, A.; Du, S.; Zhang, Z.; Wang, Q.; Wang, J.; An, R.; Wang, Y.; Wang, P.; Sun, H.; Yu, L.; Yang, S.; Xiao, T.; Gu, Q.; Shao, F.; Wang, Y.; Xiao, J.; Cao, Y.
10.1101/2024.07.10.602843 — immunology — Posted on 2024-07-10
3546 Global siRNA Screen Reveals Critical Human Host Factors of SARS-CoV-2 Multicycle Replication
Yin, X.; Pu, Y.; Yuan, S.; Pache, L.; Churas, C.; Weston, S.; Riva, L.; Simons, L. M.; Cisneros, W.; Clausen, T.; de Jesus, P.; Kim, H. N.; Fuentes, D.; Whitelock, J.; Esko, J.; Lord, M.; Mena, I.; Garcia-Sastre, A.; Hultquist, J.; Frieman, M.; Ideker, T.; Pratt, D.; Martin-Sancho, L.; Chanda, S.
10.1101/2024.07.10.602835 — systems biology — Posted on 2024-07-10
3547 Genome assembly of a diversity panel of Chenopodium quinoa
Rey, E.; Abrouk, M.; Dufau, I.; Rodde, N.; Saber, N.; Cizkova, J.; Fiene, G.; Stanschewski, C.; Jarvis, D. E.; Jellen, E. N.; Maughan, P. J.; von Baer, I.; Troukhan, M.; Kravchuk, M.; Hribova, E.; Cauet, S.; Krattinger, S.; Tester, M. A.
10.1101/2024.07.07.602379 — genomics — Posted on 2024-07-10
3553 Fluorogenic Aptamer Optimizations on a Massively Parallel Sequencing Platform
Kuo, Y.-A.; Chen, Y.-I.; Wang, Y.; Korkmaz, Z.; Yonas, S.; He, Y.; Nguyen, T. D.; Hong, S.; Nguyen, A.-T.; Kim, S.; Seifi, S.; Fan, P.-H.; Wu, Y.; Yang, Z.; Liu, H.-W.; Lu, Y.; Ren, P.; Yeh, H.-C.
10.1101/2024.07.07.602435 — biophysics — Posted on 2024-07-10
3558 Fully synthetic hydrogels promote robust crypt formation in intestinal organoids
Hushka, E. A.; Blatchley, M. R.; Macdougall, L. J.; Yavitt, F. M.; Kirkpatrick, B. E.; Bera, K.; Dempsey, P. J.; Anseth, K. S.
10.1101/2024.07.06.602364 — bioengineering — Posted on 2024-07-10
3559 Synchronous assembly of peptide anisosome
Zhou, L.; Zhu, L.; Wang, C.; Xu, T.; Wang, J.; Zhang, B.; Zhang, X.; Wang, H.
10.1101/2024.07.07.602414 — bioengineering — Posted on 2024-07-10
3561 Quantifying social roles in multi-animal videos using subject-aware deep-learning
Goss, K.; Bueno-Junior, L. S.; Stangis, K.; Ardoin, T.; Carmon, H.; Zhou, J.; Satapathy, R.; Baker, I.; Jones-Tinsley, C. E.; Lim, M. M.; Watson, B. O.; Sueur, C.; Ferrario, C. R.; Murphy, G. G.; Ye, B.; Hu, Y.
10.1101/2024.07.07.602350 — animal behavior and cognition — Posted on 2024-07-10
3567 Lung Microbiome Intervention Attenuates Herpesvirus-Induced Post-HCT Pulmonary Fibrosis Through PD-L1 Upregulation on Dendritic Cells
Perkins, J. B.; Ravi, K.; Guo, C.; Oh, G. J.; Rodriguez, B. G.; Gurczynski, S. J.; Weinberg, J. B.; Huffnagle, G. B.; O'Dwyer, D. N.; Moore, B. B.; Zhou, X.
10.1101/2024.07.06.602351 — immunology — Posted on 2024-07-10
3568 Nasal tissue-resident memory CD4+ T cells persist after influenza A virus infection and provide heterosubtypic protection
Mathew, N. R.; Gailleton, R.; Scharf, L.; Schön, K.; Strömberg, A.; Lycke, N.; Bemark, M.; Tang, K.-W.; Angeletti, D.
10.1101/2024.07.06.602325 — immunology — Posted on 2024-07-10
3571 Sexually dimorphic auditory representation in Aedes aegypti brains
Ohashi, T. S.; Xu, Y. Y. J.; Shigaki, S.; Nakamura, Y.; Lee, T.-T.; Loh, Y. M.; Mishiro-Sato, E.; Eberl, D. F.; Su, M. P.; Kamikouchi, A.
10.1101/2024.07.07.602439 — neuroscience — Posted on 2024-07-10
3574 Mouse parasubthalamic Crh neurons drive alcohol drinking escalation and behavioral disinhibition
Kreifeldt, M.; Okhuarobo, A.; Dunning, J. L.; Lopez, C.; Macedo, G.; Sidhu, H.; Contet, C.
10.1101/2024.07.06.602357 — neuroscience — Posted on 2024-07-10
3575 Single-Platelet Mapping of Jugular, Puncture-Wound Thrombi Reveals the Spatial Evolution of Platelet Activation
Rhee, S.; Pokrovskaya, I. D.; Ball, K. K.; Webb, M. W.; Kamykowski, J. A.; Zhao, O.; Driehaus, E. R.; Aronova, M. A.; Whiteheart, S. W.; Leapman, R. D.; Storrie, B.
10.1101/2024.07.07.602390 — systems biology — Posted on 2024-07-10
3579 Biomolecular condensates can function as inherent catalysts
Guo, X.; Farag, M.; Qian, N.; Yu, X.; Ni, A.; Ma, Y.; Yu, W.; King, M.; Liu, V.; Lee, J.; Min, W.; Zare, R. N.; Pappu, R. V.; Dai, Y.
10.1101/2024.07.06.602359 — biophysics — Posted on 2024-07-10
3581 Integrated functional genomic analysis identifies the regulatory variants underlying a major QTL for disease resistance in European sea bass
Mukiibi, R.; Ferraresso, S.; Franch, R.; Peruzza, L.; Rovere, G. D.; Babbucci, M.; Bertotto, D.; Toffan, A.; Pascoli, F.; Faggion, S.; Penaloza, C.; Tsigenopoulos, C. S.; Houston, R. D.; Bargelloni, L.; Robledo, D.
10.1101/2024.07.06.602346 — genetics — Posted on 2024-07-10
3582 Genomics of Neotropical biodiversity indicators: two butterfly radiations with rampant chromosomal rearrangements and hybridisation
van der Heijden, E. S.; Nasvall, K.; Beserra Nobre, C. E.; Seixas, F. A.; Campos D Maia, A.; Salazar-Carrion, P. A.; Walker, J. M.; Szczerbowski, D.; Schulz, S.; Warren, I. A.; Gavilanes Cordova, K. G.; Sanchez-Carvajal, M. J.; Chandi, F.; Arias-Cruz, A. P.; Rueda-Munoz, N.; Salazar, C.; Dasmahapatra, K. K.; Montgomery, S. H.; McClure, M.; Absolon, D. E.; Mathers, T. C.; Santos, C. A.; McCarthy, S.; Wood, J.; Bacquet, C.; Freitas, A. V.; Willmott, K. R.; Jiggins, C. D.; Elias, M.; Meier, J. I.
10.1101/2024.07.07.602206 — evolutionary biology — Posted on 2024-07-10
3583 Global-scale quantification of responses to anthropogenic stressors in six riverine organism groups
Kaijser, W.; Schuerings, C.; Schneider, A.; Prati, S.; Musiol, M.; Wenskus, F.; Brauer, V. S.; Feldhaus, L.; Wagner, C. S.; Bayer, R.; Madge Pimentel, I.; Birk, S.; Mario, B.; Dunne, L.; Enss, J.; Farias, L.; Feld, C. K.; Gillmann, S. M.; Hupalo, K.; Osakpolor, S. E.; Olberg, S.; Schlautmann, C.; Schwelm, J.; Wells, N. E.; Sures, B.; Schaefer, R. B.; Hering, D.
10.1101/2024.07.06.602319 — ecology — Posted on 2024-07-10
3586 Modulation of microglia activation after human donor retinal ganglion cell transplantation
Malechka, V.; Phay, M. H.; Augustine, J.; Rivera, J. D.; Alt, C.; Gregory-Ksander, M.; Baranov, P.
10.1101/2024.07.06.602307 — cell biology — Posted on 2024-07-10
3587 Temporal-spatially metabolic reprogramming rewires the H3K27ac landscape to enable the initiation of liver regeneration
Zheng, Q.; Li, X.; Xu, Z.; Cai, Y.; Li, F.; Xue, X.; Li, S.; Fan, G.; Sun, R.; Wu, J.; Qu, J.; Liu, R.
10.1101/2024.07.07.602368 — cell biology — Posted on 2024-07-10
3591 De Novo Design of Integrin α5β1 Modulating Proteins for Regenerative Medicine
Wang, X.; Guillem-Marti, J.; Kumar, S.; Lee, D.; Cabrerizo-Aguado, D.; Werther, R.; Alamo, K. A. E.; Zhao, Y.-T.; Nguyen, A.; Kopyeva, I.; Huang, B.; Li, J.; Hao, Y.; Li, X.; Brizuela-Velasco, A.; Murray, A. N.; Gerben, S.; Roy, A.; DeForest, C. A.; Springer, T.; Ruohola-Baker, H.; Cooper, J.; Campbell, M. G.; Manero, J. M.; Ginebra, M.-P.; Baker, D.
10.1101/2024.06.21.600123 — bioengineering — Posted on 2024-07-10
3593 Large-scale genome analyses provide insights into Hymenoptera evolution
He, C.; Yang, Y.; Zhao, X.; Li, J.; Cai, Y.; Peng, L.; Liu, Y.; Xiong, S.; Mei, Y.; Yan, Z.; Wang, J.; Xiao, S.; Teng, Z.; Gao, X.; Xue, H.; Fang, Q.; Ye, G.; Ye, X.
10.1101/2024.07.01.601370 — genomics — Posted on 2024-07-10
3596 Emerging cooperativity between Oct4 and Sox2 governs the pluripotency network in mouse early embryos
Schöler, H. R.; Hou, Y.; Nie, Z.; Jiang, Q.; Velychko, S.; Heising, S.; Bedzhov, I.; Wu, G.; Adachi, K.
10.1101/2023.10.18.562912 — developmental biology — Posted on 2024-07-10
3597 Minimally invasive serial collection of cerebrospinal fluid reveals sex-dependent differences in neuroinflammation in a rat model of mild traumatic brain injury
Karam, J.; Ashfaq, N.; Benitez, C.; Morales, V.; Partida, E.; Hernandez, M.; Yokoyama, J.; Villegas, A.; Brown, B.; Sakthivel, P.; Anderson, A. J.; Cummings, B. J.
10.1101/2024.02.26.582018 — neuroscience — Posted on 2024-07-10
3599 Brief targeting of resurgent STAT3 activation in chronic epilepsy for potent and enduring disease modification.
Hoffman, O. R.; Patterson, A.; Gohar, E.; Coleman, E.; Espina, J. E. C.; Schoenike, B.; Espinosa-Garcia, C.; Paredes, F.; Dingledine, R.; Maguire, J.; Roopra, A.
10.1101/2023.08.07.552299 — neuroscience — Posted on 2024-07-10
3600 Reproductive life history of an acoel worm
Chandra, V.; Tseng, S. E.; Kann, A. P.; Bolanos, D. M.; Srivastava, M.
10.1101/2024.07.09.602770 — zoology — Posted on 2024-07-10
3601 Global genomics of the man-o'-war (Physalia) reveal biodiversity at the ocean surface
Church, S. H.; Abedon, R. B.; Ahuja, N.; Anthony, C. J.; Ramirez, D. A.; Rojas, L. M.; Albinsson, M. E.; Alvarez Trasobares, I.; Bergemann, R. E.; Bogdanovic, O.; Burdick, D. R.; Cunha, T. J.; Damian-Serrano, A.; D'Elia, G.; Dion, K.; Doyle, T. K.; Goncalves, J. M.; Gonzalez Rajal, A.; Haddock, S. H. D.; Helm, R. R.; Le Gouvello, D.; Lewis, Z. R.; Magalhaes, B. I. M. M.; Manko, M. K.; de Mendoza, A.; Moura, C. J.; Nel, R.; Perelman, J. N.; Prieto, L.; Munro, C.; Oguchi, K.; Pitt, K. A.; Schaeffer, A.; Schmidt, A. L.; Sellanes, J.; Wilson, N. G.; Yamamoto, G.; Lazo-Wasem, E.; Simon, C.; Decker,
10.1101/2024.07.10.602499 — zoology — Posted on 2024-07-10
3602 Peroxidasin is associated with a mesenchymal-like transcriptional phenotype and promotes invasion in metastatic melanoma
Smith-Diaz, C. C.; Kumar, A.; Das, A.; Pace, P.; Chitcholtan, K.; Magon, N. J.; Hossain, S. H. M.; Eccles, M. R.; Winterbourn, C. C.; Paumann-Page, M.
10.1101/2024.04.05.588346 — cancer biology — Posted on 2024-07-10
3604 Cnidaria XIAP activates caspase-mediated cell death
Chen, Y.; Wu, M.; Yuan, Z.; Wang, Q.; Xu, H.; Sun, L.
10.1101/2024.07.06.602363 — cell biology — Posted on 2024-07-10
3605 Modulation of ribosomal subunit associations by eIF6 is critical for mitotic exit and cancer progression.
Roshan, P.; Biswas, A.; Anagnos, S.; Luebbers, R.; Harish, K.; Ahmed, S.; Li, M.; Nguyen, N.; Zhou, G.; Tedeschi, F.; Hathuc, V.; Lin, Z.; Hamilton, Z.; Origanti, S. S.
10.1101/2024.06.24.600220 — molecular biology — Posted on 2024-07-10
3606 Combining computational modeling and experimental library screening to affinity-mature VEEV-neutralizing antibody F5
Sumner, C. A.; Schwedler, J. L.; McCoy, K. M.; Holland, J. E.; Duva, V.; Gelperin, D.; Busygina, V.; Stefan, M. A.; Martinez, D. V.; Jurros, M. A.; Phillips, A. A.; Weilhammer, D. R.; Grigoryan, G.; Kent, M. S.; Harmon, B. N.
10.1101/2024.07.08.602599 — microbiology — Posted on 2024-07-10
3607 Epigenomic landscape of the human dorsal root ganglion: sex differences and transcriptional regulation of nociceptive genes
Franco-Enzastiga, U.; Inturi, N. N.; Natarajan, K.; Mwirigi, J. M.; Mazhar, K.; Schlachetzki, J. C.; Schumacher, M.; Price, T. J.
10.1101/2024.03.27.587047 — neuroscience — Posted on 2024-07-10
3608 Proteome-scale tissue mapping using mass spectrometry based on label-free and multiplexed workflows
Kwon, Y.; Woo, J.; Yu, F.; Williams, S. M.; Markillie, L. M.; Moore, R. J.; Nakaysu, E. S.; Chen, J.; Campbell-Thompson, M.; Mathews, C. E.; Nesvizhskii, A. I.; Qian, W.-J.; Zhu, Y.
10.1101/2024.03.04.583367 — systems biology — Posted on 2024-07-10
3609 Early-life glucocorticoids accelerate lymphocyte count senescence in roe deer
Lalande, L. D.; Bourgoin, G.; Carbillet, J.; Cheynel, L.; Debias, F.; Ferte, H.; Gaillard, J.-M.; Garcia, R.; Lemaitre, J.-F.; Palme, R.; Pellerin, M.; Peroz, C.; Rey, B. D.; Vuarin, P.; Gilot-Fromont, E.
10.1101/2024.05.24.595732 — physiology — Posted on 2024-07-10
3610 Single-molecule detection and super-resolution imaging with a portable and adaptable 3D-printed microscopy platform (Brick-MIC)
Moya Munoz, G. G.; Brix, O.; Klocke, P.; Harris, P. D.; Luna Piedra, J. R.; Wendler, N. D.; Lerner, E.; Zijlstra, N.; Cordes, T.
10.1101/2023.12.29.573596 — biophysics — Posted on 2024-07-10
3612 Efficient Genome Editing with Chimeric Oligonucleotide-Directed Editing
Nguyen, L. T.; Rakestraw, N. R.; Pizzano, B. L. M.; Young, C. B.; Huang, Y.; Beerensson, K. T.; Fang, A.; Antal, S. G.; Anamiss, K. V.; Peggs, C. M. D.; Yan, J.; Jing, Y.; Burdine, R. D.; Adamson, B.; Toettcher, J. E.; Myhrvold, C.; Jain, P. K.
10.1101/2024.07.09.602710 — bioengineering — Posted on 2024-07-10
3614 Activation of Polycystin-1 Signaling by Binding of Stalk-derived Peptide Agonists
Pawnikar, S.; Magenheimer, B. S.; Joshi, K.; Nevarez-Munoz, E.; Haldane, A.; Maser, R. L.; Miao, Y.
10.1101/2024.01.06.574465 — biochemistry — Posted on 2024-07-10
3616 Regulatory genome annotation of 33 insect species
Asma, H.; Tieke, E.; Deem, K. D.; Rahmat, J.; Dong, T.; Huang, X.; Tomoyasu, Y.; Halfon, M. S.
10.1101/2024.01.23.576926 — genomics — Posted on 2024-07-10
3617 A Developmental Mechanism to Regulate Alterna6ve Polyadenyla6on in an Adult Stem Cell Lineage
Gallicchio, L.; Reis Matias, N.; Morales-Polanco, F.; Nava, I.; Stern, S.; Zeng, Y.; Fuller, M. T.
10.1101/2024.03.18.585561 — developmental biology — Posted on 2024-07-10
3618 Acute BRCAness Induction and AR Signaling Blockage through CDK12/7/9 Degradation Enhances PARP Inhibitor Sensitivity in Prostate Cancer
Gui, F.; Jiang, B.; Jiang, J.; He, Z.; Tsujino, T.; Takai, T.; Arai, S.; Pana, C.; Koellermann, J.; Bradshaw, G. A.; Eisert, R.; Kalocsay, M.; Fassl, A.; Balk, S. P.; Kibel, A. S.; Jia, L.
10.1101/2024.07.09.602803 — cancer biology — Posted on 2024-07-10
3620 The West African lungfish secretes a living cocoon during aestivation with uncertain antimicrobial function
Palominos, M. F.; Bharadwaj, R.; Tralka, C.; Trang, K.; Aka, D.; Alami, M.; Andrews, D.; Bartlett, B.; Golde, C.; Liu, J.; Le-Pedroza, M.; Perrot, R.; Seiter, B.; Sparrow, C.; Shapira, M.; Martin, C. H.
10.1101/2024.07.05.602297 — physiology — Posted on 2024-07-10
3621 Single-cell analysis of pediatric acute myeloid leukemia samples uncovers treatment-resistant stem and mast cells
Ohlstrom, D.; Bakhtia, M.; Mumme, H.; Michaud, M.; Chien, F.; Pilcher, W.; Satpathy, S.; Bhasin, S.; Bhasin, M.
10.1101/2024.07.09.602801 — cancer biology — Posted on 2024-07-10
3623 Generation of an inflammatory niche in an injectable hydrogel depot through recruitment of key immune cells improves efficacy of mRNA vaccines
Meany, E. L.; Klich, J. H.; Jons, C. K.; Mao, T.; Chaudhary, N.; Utz, A.; Baillet, J.; Song, Y. E.; Saouaf, O. M.; Ou, B. S.; Williams, S. C.; Eckman, N.; Irvine, D. J.; Appel, E.
10.1101/2024.07.05.602305 — bioengineering — Posted on 2024-07-10
3624 Extracellular ISG15 triggers ISGylation via a type-I interferon independent mechanism to regulate host response during virus infection
Miller, L. G.; Chiok, K.; Mariasoosai, C.; Mohanty, I.; Pandit, S.; Mehari, L.; Haas, A. L.; Natesan, S.; Miura, T. A.; Bose, S.
10.1101/2024.07.05.602290 — immunology — Posted on 2024-07-10
3625 Esophageal epithelial Ikkβ deletion promotes eosinophilic esophagitis in experimental allergy mouse model
Clevenger, M. H.; Wei, C.; Karami, A. L.; Tsikretsis, L.; Carlson, D. A.; Pandolfino, J. E.; Gonsalves, N.; Winter, D. R.; Whelan, K. A.; Tetreault, M.-P.
10.1101/2024.07.05.602313 — immunology — Posted on 2024-07-10
3627 A Novel Ex Vivo Approach for Investigating Profibrotic Macrophage Polarization Using Murine Precision-Cut Lung Slices
Vierhout, M.; Ayoub, A.; Ali, P.; Kumaran, V.; Naiel, S.; Isshiki, T.; Koenig, J. F.; Kolb, M. R.; Ask, K.
10.1101/2024.07.05.602278 — immunology — Posted on 2024-07-10
3628 Main Sequence of Human Luminance-Evoked Pupil Dynamics
Coutinho, J. D.; Huang, J.; Lefevre, P.; Blohm, G.; Munoz, D. P.
10.1101/2024.07.05.602284 — neuroscience — Posted on 2024-07-10
3631 Differential Anti-Inflammatory Effects of Electrostimulation in a Standardized Setting
Di Pietro, B.; Villata, S.; Dal MOnego, S.; Degasperi, M.; Ghini, V.; Guarnieri, T.; Plaksienko, A.; Liu, Y.; Pecchioli, V.; Manni, L.; Tenori, L.; Licastro, D.; Angelini, C.; Napione, L.; Frascella, F.; Nardini, C.
10.1101/2024.07.05.602081 — systems biology — Posted on 2024-07-10
3633 Rapid evolution of gene expression patterns in flowering plants
Schuster, C.; Gabel, A.; Drost, H.-G.; Grosse, I.; Leyser, O.; Meyerowitz, E. M.
10.1101/2024.07.08.602577 — plant biology — Posted on 2024-07-10
3636 Nemacounter: A user-friendly software to accurately phenotype SCN cysts
Mejias, J.; Kozlowski, D. K. L.; Goshon, J.; Maier, T. R.; Baum, T. J.
10.1101/2024.07.07.602381 — plant biology — Posted on 2024-07-10
3643 Evolutionary dynamics in the decades preceding acute myeloid leukaemia
Watson, C.; Poon, Y. P. G. G.; MacGregor, H. A. J.; Fonseca, A. V. A.; Apostolidou, S.; Gentry-Maharaj, A.; Menon, U.; Blundell, J. R.
10.1101/2024.07.05.602251 — cancer biology — Posted on 2024-07-10
3645 Charge distribution and helical content tune the binding of septins amphipathic helix domain to lipid membranes
Edelmaier, C. J.; Klawa, S. J.; Mofidi, S. M.; Wang, Q.; Bhonge, S.; Vogt, E. J. D.; Curtis, B. N.; Shi, W.; Hanson, S. M.; Klotsa, D.; Forest, M. G.; Gladfelter, A. S.; Freeman, R.; Nazockdast, E.
10.1101/2024.07.05.602292 — biophysics — Posted on 2024-07-10
3646 Tumor Subtype Classification Tool for HPV-associated Head and Neck Cancers
Li, S.; Grab, B. F.; Qin, T.; Soppe, S.; Lopez, E.; Patil, S.; D'Silva, N. J.; Rozek, L. S.; Sartor, M. A.
10.1101/2024.07.05.601906 — bioinformatics — Posted on 2024-07-10
3648 Draft genome of Palmaria palmata and intraspecific genetic variations in the North-East Atlantic
Rosignoli, S.; Inaba, M.; Schmid, M.; McHale, M.; Fort, A.; Edwards, M. D.; Mols Mortensen, A.; Bartle, R.; Endal, A.; Baud, A.; Maggs, C.; Sulpice, R.
10.1101/2024.07.05.602248 — genomics — Posted on 2024-07-10
3650 Pathogenicity is associated with population structure in a fungal pathogen of humans
Hatmaker, E. A.; Barber, A. E.; Drott, M. T.; Sauters, T. J. C.; Alastruey-Izquierdo, A.; Garcia-Hermoso, D.; Kurzai, O.; Rokas, A.
10.1101/2024.07.05.602241 — evolutionary biology — Posted on 2024-07-10
3656 A snapshot of the Physcomitrella N-terminome reveals N-terminal methylation of organellar proteins
Hoernstein, S. N. W.; Schlosser, A.; Fiedler, K.; van Gessel, N.; Igloi, G. L.; Lang, D.; Reski, R.
10.1101/2024.06.11.598444 — plant biology — Posted on 2024-07-10
3657 Resolving multi-image spatial lipidomic responses to inhaled toxicants by machine learning
Stevens, N. C.; Shen, T.; Martinez, J.; Evans, V. J.; Domanico, M. C.; Neumann, E. K.; Van Winkle, L. S.; Fiehn, O.
10.1101/2024.07.05.602264 — pharmacology and toxicology — Posted on 2024-07-10
3661 Structural basis for CCR6 modulation by allosteric antagonists
Wasilko, D. J.; Gerstenberger, B. S.; Farley, K. A.; Li, W.; Alley, J.; Schnute, M. E.; Unwalla, R. J.; Victorino, J.; Crouse, K. K.; Ding, R.; Sahasrabudhe, P. V.; Vincent, F.; Frisbie, R. K.; Dermenci, A.; Flick, A.; Choi, C.; Chinigo, G.; Mousseau, J. J.; Trujillo, J. I.; Nuhant, P.; Mondal, P.; Lombardo, V.; Lamb, D.; Hogan, B. J.; Minhas, G. S.; Segala, E.; Oswald, C.; Windsor, I. W.; Han, S.; Rappas, M.; Cooke, R. M.; Calabrese, M. F.; Berstein, G.; Thorarensen, A.; Wu, H.
10.1101/2024.04.05.588354 — biochemistry — Posted on 2024-07-10
3662 Machine Learning Uncovers the Transcriptional Regulatory Network for the Production Host Streptomyces albidoflavus
Jönsson, M.; Sigrist, R.; Gren, T.; Semenov Petrov, M.; Marcussen, N.; Svetlova, A.; Charusanti, P.; Palsson, B. O.; Yang, L.; Özdemir, E.
10.1101/2024.01.09.574332 — genomics — Posted on 2024-07-10
3663 An integrative taxonomy approach reveals Saccharomyces chiloensis sp. nov. as a newly discovered species from Coastal Patagonia
Pena, T. A.; Villarreal, P.; Agier, N.; Chiara, M. D.; Barria, T.; Urbina, K.; Villarroel, C. A.; Santos, A. R. O.; Rosa, C. A.; Nespolo, R. F.; Liti, G.; Fischer, G.; Cubillos, F.
10.1101/2024.04.29.591617 — genetics — Posted on 2024-07-10
3664 Does bumblebee preference of continuous over interrupted strings in string-pulling tasks indicate means-end comprehension?
Wen, C.; Lu, Y.; Solvi, C.; Dong, S.; Cai, W.; Haijun, X.; Jun, W. X.; Kui, D. S.; Wen, J.; Peng, F.; Chittka, L.
10.1101/2024.04.02.587731 — ecology — Posted on 2024-07-10
3665 UPF1 is required for gene expression in mitochondria and paternal mtDNA clearance during spermatogenesis
Wright, M. T.; Singh, A. K.; Dixon, H. L.; Price, E. M.; Connolly, E. C.; di Maio, A.; Barlow, J. P.; Catoni, M.; Fan, Y.; Brogna, S.
10.1101/2024.05.10.591322 — cell biology — Posted on 2024-07-10
3668 Preclinical evaluation of the novel CHDI-650 PET ligand for non-invasive quantification of mutant huntingtin aggregates in Huntington's disease
Zajicek, F.; Verhaeghe, J.; de Lombaerde, S.; Van Eetveldt, A.; Miranda, A.; Munoz-Sanjuan, I.; Dominguez, C.; Khetarpal, V.; Bard, J.; Liu, L.; Staelens, S.; Bertoglio, D.
10.1101/2024.05.16.594492 — neuroscience — Posted on 2024-07-10
3670 Alternative TSS use is widespread in Cryptococcus fungi in response to environmental cues and regulated genome-wide by the transcription factor Tur1
Dang, T. T. V.; Maufrais, C.; Colin, J.; Moyrand, F.; Mouyna, I.; Coppee, J.-Y.; Onyishi, C. U.; Lipecka, J.; Guerrera, I. C.; May, R. C.; Janbon, G.
10.1101/2023.07.18.549460 — molecular biology — Posted on 2024-07-10
3673 BRAT1 - a new therapeutic target for glioblastoma
Haydo, A. S.; Schmidt, J. H.; Crider, A.; Kögler, T.; Ertl, J.; Hehlgans, S.; Hoffmann, M. E.; Rathore, R.; Güllülü, O.; Wang, Y.; Zhang, X.; Herold-Mende, C.; Pampaloni, F.; Tegeder, I.; Dikic, I.; Dai, M.; Rödel, F.; Kögel, D.; Linder, B.
10.1101/2024.07.08.602519 — cancer biology — Posted on 2024-07-10
3674 Efficient Genome Editing with Chimeric Oligonucleotide-Directed Editing
Nguyen, L. T.; Rakestraw, N. R.; Pizzano, B. L.; Young, C. B.; Huang, Y.; Beerensson, K. T.; Fang, A.; Antal, S. G.; Anamiss, K. V.; Peggs, C. M.; Yan, J.; Jing, Y.; Burdine, R. D.; Adamson, B.; Toettcher, J. E.; Myhrvold, C.; Jain, P. K.
10.1101/2024.07.09.602710 — bioengineering — Posted on 2024-07-10
3679 RBM10 loss induces aberrant splicing of cytoskeletal and extracellular matrix mRNAs and promotes metastatic fitness.
Krishnamoorthy, G. P.; Glover, A. R.; Untch, B. R.; Sigcha-Coello, N. F.; Xu, B.; Vukel, D.; Liu, Y.; Tiedje, V.; Berman, K.; Tamarapu, P. P.; Acuna-Ruiz, A.; Saqcena, M.; de Stanchina, E.; Boucai, L.; Ghossein, R. A.; Knauf, J. A.; Abdel-Wahab, O.; Bradley, R.; Fagin, J. A.
10.1101/2024.07.09.602730 — cancer biology — Posted on 2024-07-10
3681 Transcriptional Characterization of Resistance in Early Drug Response
Ruoff, C.; Mitchell, A.; Mondal, P.; Gopalan, V.; Gottesman, M.; Hannenhalli, S.
10.1101/2024.07.05.602281 — cancer biology — Posted on 2024-07-10
3684 CLEC18A interacts with sulfated GAGs and controls clear cell renal cell carcinoma progression
Jonsson, G.; Hofmann, M.; Mereiter, S.; Hartley-Tassell, L.; Sakic, I.; Oliveira, T.; Hoffmann, D.; Novatchkova, M.; Schleiffer, A.; Penninger, J. M.
10.1101/2024.07.08.602586 — cancer biology — Posted on 2024-07-10
3685 Targeting NOTCH2-JAG1 juxtacrine signaling reverses macrophage-mediated tumor resistance to taxol
Yu, F.; Zhou, Q.; Zhou, T.; Xie, Y.; Zhang, P.; He, W.; Yu, W.; Cheng, A.; Liu, H.; Wu, Q.; Ma, X.; Guo, J.; Zhou, Y.; Shi, J.; Yang, Z.
10.1101/2024.07.08.602467 — cancer biology — Posted on 2024-07-10
3687 Osmotic Stress Influences Microtubule Drug Response Via WNK1 Kinase Signaling
Monfort-Vengut, A.; Sanz-Gomez, N.; Ballesteros-Sanchez, S.; Ortigosa, B.; Cambon, A.; Ramos, M.; Montes-San Lorenzo, A.; Rosa-Rosa, J. M.; Martinez-Lopez, J.; Sanchez-Prieto, R.; Sotillo, R.; de Carcer, G.
10.1101/2024.07.08.602030 — cancer biology — Posted on 2024-07-10
3689 Effective in vivo binding energy landscape illustrates kinetic stability of RBPJ-DNA binding
Huynh, D.; Hoffmeister, P.; Friedrich, T.; Zhang, K.; Bartkuhn, M.; Ferrante, F.; Giaimo, B. D.; Kovall, R.; Borggrefe, T.; Oswald, F.; Gebhardt, J. C. M.
10.1101/2023.12.19.572376 — biophysics — Posted on 2024-07-10
3694 The sperm hook in house mice: a functional adaptation for migration and self-organised behaviour
Ryu, H.; Nam, K.; Lee, B. E.; Jeong, Y.; Lee, S.; Kim, J.; Hyun, Y.-M.; Kim, J.-I.; Park, J.-H.
10.1101/2024.02.19.581047 — cell biology — Posted on 2024-07-10
3695 Purging viral latency by a bifunctional HSV-vectored therapeutic vaccine in chronically SIV-infected macaques
Wen, Z.; Li, P.; Yuan, Y.; Wang, C.; Li, M.; Wang, H.; Shi, M.; He, Y.; Cui, M.; Chen, L.; Sun, C.
10.1101/2024.02.20.581122 — microbiology — Posted on 2024-07-10
3696 Ly6G+Granulocytes-derived IL-17 limits protective host responses and promotes tuberculosis pathogenesis
Sharma, P.; Sharma, R. D.; Das, M.; Sarkar, B.; Singh, L.; Jain, N.; Chaturvedi, S.; Mehra, L.; Rathee, A.; Sharma, S.; Shihui, F.; Lee, A.; Kumar, P. N.; Das, P.; Viswanathan, V.; Kornfeld, H.; Howland, S.; Babu, S.; Nandicoori, V.; Singhal, A.; Kumar, D.
10.1101/2023.10.05.561061 — immunology — Posted on 2024-07-10
3700 Generation of the First Transgenic Line of the Iconic Coral Reef Fish Amphiprion ocellaris
Graham, G. J.; Ibanez, E. M.; Mitchell, L. J.; Weis, K. E.; Raetzman, L. T.; Cortesi, F.; Rhodes, J. S.
10.1101/2024.06.05.597662 — bioengineering — Posted on 2024-07-10
3701 A Comprehensive Resource for Exploring Antiphage Defense: DefenseFinder Webservice, Wiki and Databases.
Tesson, F.; Planel, R.; Egorov, A. A.; Georjon, H.; Vaysset, H.; Brancotte, B.; Neron, B.; Mordret, E.; Atkinson, G. C.; Bernheim, A.; Cury, J.
10.1101/2024.01.25.577194 — genomics — Posted on 2024-07-10
3702 Contextualising samples: Supporting reference genomes of European biodiversity through sample and associated metadata collection
Boehne, A.; Fernandez, R.; Leonard, J. A.; McCartney, A. M.; McTaggart, S.; Melo-Ferreira, J.; Monteiro, R.; Oomen, R. A.; Vinnere Pettersson, O.; Struck, T. H.
10.1101/2023.06.28.546652 — genomics — Posted on 2024-07-10
3705 Membrane potential mediates an ancient mechano-transduction mechanism for multi-cellular homeostasis
Mukherjee, A.; Huang, Y.; Elgeti, J.; Oh, S.; Abreu, J.; Neliat, A. R.; Schuttler, J.; Su, D.; Dupre, C.; Benites, N. C.; Liu, X.; Peshkin, L.; Barboiu, M.; Stocker, H.; Kirschner, M. W.; Basan, M.
10.1101/2023.11.02.565386 — cell biology — Posted on 2024-07-10
3706 N-acetyl-transferases required for iron uptake and aminoglycoside resistance promote virulence lipid production in M. marinum
Jones, B. S.; Pareek, V.; Hu, D. D.; Weaver, S. D.; Syska, C.; Galfano, G.; Champion, M.; Champion, P. A.
10.1101/2024.07.05.602253 — microbiology — Posted on 2024-07-10
3707 Evolution of genotypic and phenotypic diversity in multispecies biofilms
Amador, C. I.; Moskovitz, S. Z.; Maccario, L.; Herschend, J.; Kramer, I. S.; Jeckel, H.; Cooper, V. S.; Drescher, K.; Neu, T. R.; Burmolle, M.; Roder, H. L.
10.1101/2023.10.08.561388 — microbiology — Posted on 2024-07-10
3708 Converging Topographic Axes of Connectivity and Genetic Architectures Scaffold Cortical Patterning
Li, D.; Wang, Y.; Ma, L.; Wang, Y.; Cheng, L.; Liu, Y.; Shi, W.; Lu, Y.; Wang, H.; Gao, C.; Erichsen, C.; Zhang, Y.; Yang, Z.; Eickhoff, S.; Chen, C.-h.; Jiang, T.; Chu, C.; Fan, L.
10.1101/2023.09.06.556618 — neuroscience — Posted on 2024-07-10
3711 Rapid loss of genetic variation and increased inbreeding in small and isolated populations of Norwegian wild reindeer
Hansen, B. B.; Peeters, B.; Flagstad, O.; Roed, K. H.; Martin, M. D.; Jensen, H.; Burnett, H. A.; Bieker, V. C.; Mysterud, A.; Sun, X.; Cote, S. D.; Robert, C.; Rolandsen, C. M.; Strand, O.
10.1101/2024.07.09.598942 — genetics — Posted on 2024-07-09
3712 Dynamic stress- and inflammatory-based regulation of psychiatric risk loci in human neurons
Retallick-Townsley, K. G.; Lee, S.; Cartwright, S.; Cohen, S.; Sen, A.; Jia, M.; Young, H.; Dobbyn, L.; Deans, M.; Fernandez-Garcia, M.; Huckins, L. M.; Brennand, K. J.
10.1101/2024.07.09.602755 — genetics — Posted on 2024-07-09
3715 A dendritic substrate for temporal diversity of cortical inhibition
Morabito, A.; Zerlaut, Y.; Dhanasobhon, D.; Berthaux, E.; Tzilivaki, A.; Moneron, G.; Cathala, L.; Poirazi, P.; Bacci, A.; DiGregorio, D.; Lourenco, J.; Rebola, N.
10.1101/2024.07.09.602783 — neuroscience — Posted on 2024-07-09
3716 Environmental controls on crenarchaeol distributions in hydrothermal springs
Calhoun, A. N.; Blewett, J.; Colman, D.; Amenabar, M. J.; Harris, C. M.; Boyd, E.; Pearson, A.; Leavitt, W. D.
10.1101/2024.07.09.602736 — microbiology — Posted on 2024-07-09
3719 Metagenomic insights into the development of microbial communities of straw and leaf composts.
Kimeklis, A. K.; Gladkov, G. V.; Orlova, O. V.; Lisina, T. O.; Afonin, A. M.; Aksenova, T. S.; Kichko, A. A.; Lapidus, A.; Abakumov, E. V.; Andronov, E. E.
10.1101/2024.07.08.602579 — microbiology — Posted on 2024-07-09
3720 Combining computational modeling and experimental library screening to affinity-mature VEEV-neutralizing antibody F5
Sumner, C. A.; Schwedler, J. L.; McCoy, K. M.; Holland, J. E.; Duva, V.; Gelperin, D.; Busygina, V.; Stefan, M. A.; Martinez, D. V.; Jurros, M. A.; Phillips, A. A.; Weilhammer, D. R.; Grigoryan, G.; Kent, M. S.; Harmon, B. N.
10.1101/2024.07.08.602599 — microbiology — Posted on 2024-07-09
3722 Transcription Factors DksA and PsrA are synergistic contributors to L. pneumophila virulence in Acathamoeba castellanii protozoa
Graham, C. I.; MacMartin, T. L.; Penner, T. V.; Beck, J. C.; Gierys, A. J.; Prehna, G.; de Kievit, T. R.; Brassinga, A. K. C.
10.1101/2024.07.09.602712 — microbiology — Posted on 2024-07-09
3723 Bacteriophage resistance evolution in a honey bee pathogen
Van Leuven, J.; Miller, C.; Peters, T.; Spencer, E.; Eline, Y.; Paull, K.; Saucedo, L.; Linzan, K.
10.1101/2024.07.09.602782 — microbiology — Posted on 2024-07-09
3724 Genome-resolved year-round dynamics reveal a broad range of giant virus microdiversity
Fang, Y.; Meng, L.; Xia, J.; Gotoh, Y.; Hayashi, T.; Nagasaki, K.; Endo, H.; Okazaki, Y.; Ogata, H.
10.1101/2024.07.08.602415 — microbiology — Posted on 2024-07-09
3725 Illuminating microbial phosphorus cycling in deep-sea cold seep sediments using protein language models
Zhang, C.; He, Y.; Wang, J.; Chen, T.; Baltar, F.; Hu, M.; Liao, J.; Xiao, X.; Li, Z.-R.; Dong, X.
10.1101/2024.07.09.602434 — microbiology — Posted on 2024-07-09
3727 TgATG9 is required for autophagosome biogenesis and maintenance of chronic infection in Toxoplasma gondii
Thaprawat, P.; Zhang, Z.; Rentchler, E. C.; Wang, F.; Chalasani, S.; Giuliano, C. J.; Lourido, S.; Di Cristina, M.; Klionsky, D. J.; Carruthers, V. B.
10.1101/2024.07.08.602581 — microbiology — Posted on 2024-07-09
3728 The Haemagglutinin Genes of the UK Clade 2.3.4.4b H5N1 Avian Influenza Viruses from 2020 to 2022 Retain Strong Avian Phenotype
Yang, J.; Daines, R.; Chang, P.; Karunarathna, T. K.; Qureshi, M.; Sadeyen, J.-R.; James, J.; Banyard, A. C.; Slomka, M. J.; Brown, I. H.; Iqbal, M.
10.1101/2024.07.09.602706 — microbiology — Posted on 2024-07-09
3731 Optogenetic control of a horizontally acquired region in yeast prevent stuck fermentations
Figueroa, D.; Ruiz, D.; Tellini, N.; De Chiara, M.; Kessi-Perez, E. I.; Martinez, C.; Liti, G.; Querol, A.; Guillamon, J. M.; Salinas, F.
10.1101/2024.07.09.602721 — microbiology — Posted on 2024-07-09
3739 Structural Basis for the Activation of Proteinase-Activated Receptors (PARs) by Endogenous Ligands
Kang, Y.; Lyu, Z.; Lyu, X.; Xia, G.; Carney, D.; Alves, V. M.; Falk, M.; Arora, N.; Zou, H.; McGrath, A.
10.1101/2024.07.08.602624 — biochemistry — Posted on 2024-07-09
3743 The RRM domain-containing protein Rbp3 interacts with ribosomes and the 3' ends of mRNAs encoding photosynthesis proteins
Hemm, L.; Lichtenberg, E.; Tholen, S.; Reimann, V.; Kakazu, K.; Machida, S.; Mahbub, M.; Schilling, O.; Wilde, A.; Watanabe, S.; Mullineaux, C. W.; Hess, W. R.
10.1101/2024.07.09.602696 — microbiology — Posted on 2024-07-09
3744 Co-option of mitochondrial nucleic acid sensing pathways by HSV-1 UL12.5 for reactivation from latent Infection
Cuddy, S.; Krakowiak, P. A.; Flores, M. E.; Whitford, A. L.; Dochnal, S. A.; Babnis, A.; Miyake, T.; Tigano, M.; Engel, D. A.; Cliffe, A. R.
10.1101/2024.07.06.601241 — microbiology — Posted on 2024-07-09
3747 A genome-wide CRISPR/Cas9 screen identifies genes that regulate the cellular uptake of α-synuclein fibrils by modulating heparan sulfate proteoglycans
Vanderperre, B.; Muraleedharan, A.; Dorion, M.-F.; Larroquette, F.; Del Cid Pellitero, E.; Rajakulendran, N.; Chen, C. X.- Q.; Lariviere, R.; Michaud-Tardif, C.; Chidiac, R.; Lipuma, D.; Macleod, G.; Thomas, R.; Wang, Z.; Reintsch, W. E.; Luo, W.; Shlaifer, I.; Zhang, F.; Xia, K.; Steinhart, Z.; Linhardt, R. J.; Trempe, J.-F.; Liu, J.; Durcan, T.; Angers, S.; Fon, E. A.
10.1101/2023.09.29.560170 — cell biology — Posted on 2024-07-09
3750 Focal cortical dysplasia type II-dependent maladaptive myelination in the human frontal lobe
Donkels, C.; Huber, S.; Demerath, T.; Scheiwe, C.; Schah, M. J.; Heers, M.; Urbach, H.; Schulze-Bonhage, A.; Prinz, M.; Haeussler, U.; Vlachos, A.; Beck, J.; Nakagawa, J. M.; Haas, C. A.
10.1101/2024.03.02.582894 — neuroscience — Posted on 2024-07-09
3752 DNA Origami Signal Amplification in LateralFlow Immunoassays
Ijäs, H.; Trommler, J.; Nguyen, L.; van Rest, S.; Nickels, P. C.; Liedl, T.; Urban, M. J.
10.1101/2024.07.05.602214 — biophysics — Posted on 2024-07-09
3758 Cell Simulation as Cell Segmentation
Jones, D. C.; Elz, A. E.; Hadadianpour, A.; Ryu, H.; Glass, D. R.; Newell, E. W.
10.1101/2024.04.25.591218 — bioinformatics — Posted on 2024-07-09
3759 VaccineDesigner: A Web-based Tool for Streamlined Epitope-based Vaccine Design
Trygoniaris, D.; Anna, K.; Paraskeva, A.; Dhusku, E.; Tzimagiorgis, G.; Yiangou, M.; Kotzamanidis, C.; Malousi, A.
10.1101/2024.03.20.585850 — bioinformatics — Posted on 2024-07-09
3763 Repeated horizontal acquisition of lagriamide-producing symbionts in Lagriinae beetles
Uppal, S.; Waterworth, S. C.; Nick, A.; Vogel, H.; Florez, L.; Kaltenpoth, M.; Kwan, J. C.
10.1101/2024.01.23.576914 — genomics — Posted on 2024-07-09
3768 Design, infectability, and transcriptomic analysis of transregionally differentiated and scalable lung organoids derived from adult bronchial cells.
Reyes Valenzuela, A.; Turner, M.; Markarian, N.; Lachance-Brais, C.; Hanrahan, J. W.; Vali, H.; Vidal, S.; Mongeau, L.
10.1101/2024.07.02.601655 — cell biology — Posted on 2024-07-09
3769 Chromatin endogenous cleavage provides a global view of RNA polymerase II transcription kinetics
VanBelzen, J.; Sakelaris, B.; Brickner, D. G.; Marcou, N.; Riecke, H.; Mangan, N.; Brickner, J. H.
10.1101/2024.07.08.602535 — molecular biology — Posted on 2024-07-09
3772 Neural Stem Cell Relay from B1 to B2 cells in the adult mouse Ventricular-Subventricular Zone
Cebrian-Silla, A.; Assis Nascimento, M.; Mancia Leon, W.; Gonzalez-Granero, S.; Romero-Rodriguez, R.; Obernier, K.; Steffen, D. M.; Lim, D. A.; Garcia-Verdugo, J. M.; Alvarez-Buylla, A.
10.1101/2024.06.28.600695 — neuroscience — Posted on 2024-07-09
3776 Targeting NRP1 with EG00229 induces neurovascular permeability
Dragoni, S.; Brash, J. T.; Fantin, A.; Burridge, C.; Denti, L.; Turowski, P.; Ruhrberg, C.
10.1101/2023.11.07.564946 — physiology — Posted on 2024-07-09
3777 The interplay between biomolecular assembly and phase separation
Bartolucci, G.; Haugerud, I. S.; Michaels, T. C. T.; Weber, C. A.
10.1101/2023.04.18.537072 — biophysics — Posted on 2024-07-09
3781 ESRP2-microRNA-122 axis directs the postnatal onset of liver polyploidization and maturation
Bangru, S.; Chen, J.; Baker, N. J.; Das, D.; Chembazhi, U. V.; Derham, J. M.; Chorghade, S. G.; Arif, W.; Alencastro, F.; Duncan, A. W.; Carstens, R. P.; Kalsotra, A.
10.1101/2024.07.06.602336 — developmental biology — Posted on 2024-07-09
3784 O-glycosylation of intrinsically disordered regions regulates homeostasis of membrane proteins in streptococci
Rahman, M. M.; Zamakhaeva, S.; Rush, J. S.; Chaton, C. T.; Kenner, C. W.; Hla, Y. M.; Tsui, H.-C. T.; Uversky, V. N.; Winkler, M. E.; Korotkov, K. V.; Korotkova, N.
10.1101/2024.05.05.592596 — microbiology — Posted on 2024-07-09
3785 Taxonomy, nomenclature, and identification of the giant hummingbirds (Patagona spp.) (Aves: Trochilidae)
Williamson, J. L.; Gadek, C. R.; Robinson, B. W.; Bautista, E.; Bauernfeind, S. M.; Baumann, M. J.; Gyllenhaal, E. F.; Marra, P. P.; Ricote, N.; Singh, N. D.; Valqui, T.; Witt, C. C.
10.1101/2024.07.03.601580 — zoology — Posted on 2024-07-09
3787 Benchmarking reveals superiority of deep learning variant callers on bacterial nanopore sequence data
Hall, M. B.; Wick, R. R.; Judd, L. M.; Nguyen, A. N. T.; Steinig, E. J.; Xie, O.; Davies, M. R.; Seemann, T.; Stinear, T. P.; Coin, L. J. M.
10.1101/2024.03.15.585313 — bioinformatics — Posted on 2024-07-09
3788 Behavioral and neural correlates of social hierarchy formation in a sex-changing fish
Quertermous, H. M.; Kamstra, K.; van der Burg, C. A.; Muncaster, S.; Todd, E. V.; Jasoni, C. L.; Brown, C.; Gemmell, N. J.
10.1101/2024.07.04.602141 — animal behavior and cognition — Posted on 2024-07-09
3789 Gut microbiota regulates food intake in a rodent model of binge-eating disorder
Demangeat, T.; Loison, L.; Hure, M.; do Rego, J.-L.; Dechelotte, P.; Achamrah, N.; Coëffier, M.; Ribet, D.
10.1101/2024.07.05.602243 — animal behavior and cognition — Posted on 2024-07-09
3793 Legionella felix sp. - A novel Legionella species isolated in Israel from hot tap water
Zizelski Valenci, G.; Ohad, S.; Robinstein, M.; Assaly, S.; Kutikov, I.; Groisman, L.; Murik, O.; Zeevi, D. A.; Ben David, R.; Farber, A.; Dveyrin, Z.; Rorman, E.; Nissan, I.
10.1101/2023.09.14.557692 — microbiology — Posted on 2024-07-09
3795 Unbiased multiplex antigen screening of Cerebrospinal Fluid detects microbial and autoantigenic epitopes associated with Multiple Sclerosis
Barton, N. J.; Tran, K.; Olson, M. N.; Deshpande, M.; Radu, I.; Francis, N.; Kurban, M.; Orszulak, A. R.; Chigas, S. M.; Sundstrom, J.; Dawes, P.; Murray, L. F.; Ionete, C.; Lim, E. T.; Hemond, C. C.; Chan, Y.
10.1101/2024.07.05.602301 — immunology — Posted on 2024-07-09
3796 A Systematic Review of the Neuroprotective Role and Biomarker Potential of GDF15 in Neurodegeneration
Isik, F. I.; Thomson, S.; Cueto, J. F.; Spathos, J.; Breit, S. N.; Tsai, V. W. W.; Brown, D. A.; Finney, C. A.
10.1101/2024.07.07.600156 — neuroscience — Posted on 2024-07-09
3798 Probing tau citrullination in Alzheimer's disease brains and mouse models of tauopathy
Liang, H.; Hunt, J. B.; Ma, C.; Kovalenko, A.; Calahatian, J. T.; Pedersen, C.; Liu, H.; Serrano, M. E.; Blazier, D.; Watler, M.; Rocha-Rangel, P.; Saunders, C.; Blair, L. J.; Breydo, L.; Nash, K.; Quadri, Z.; Kraemer, B.; Nelson, P.; Norris, C.; Abner, E. L.; Uversky, V. N.; Chaput, D.; Selenica, M.-L. B.; Lee, D. C.
10.1101/2024.07.06.601399 — neuroscience — Posted on 2024-07-09
3800 Additive effects of cerebrovascular disease functional connectome phenotype and plasma p-tau181 on longitudinal neurodegeneration and cognitive outcomes
Chong, J. S. X.; Ji, F.; Hilal, S.; Chong, J. R.; Lau, J. M.; Tong, N. R. J.; Tan, B. Y.; Venketasubramanian, N.; Lai, M. K. P.; Chen, C. L.-H.; Zhou, J. H.
10.1101/2024.07.09.602637 — neuroscience — Posted on 2024-07-09
3801 Representation of visual uniformity in the lateral prefrontal cortex
Ge, Y.; Taschereau-Dumouchel, V.; Lin, Q.; Moharramipour, A.; Sun, Z.; Lau, H.
10.1101/2024.07.07.602149 — neuroscience — Posted on 2024-07-09
3805 Membrane Contact Sites Between Chloroplasts and Pathogen Interface Underpin Plant Focal Immune Responses
Yuen, E. L. H.; Savage, Z.; Adamkova, V.; Vuolo, C.; Zhou, Y.; Tumtas, Y.; Erickson, J. L.; Prautsch, J.; Balmez, A. I.; Stuttmann, J.; Duggan, C.; Rivetti, F.; Molinari, C.; Schattat, M.; Bozkurt, T. O.
10.1101/2021.10.08.463641 — plant biology — Posted on 2024-07-09
3807 Comparative vitreous proteomic profiling of proliferative diabetic retinopathy and diabetic with no-retinopathy subjects implicates impaired autophagy in DR pathogenesis
Sharma, S.; Hameed, S. S.; Vishwakarma, S.; Chhablani, J.; Tyagi, M.; Narayanan, R.; Pappuru, R. R.; Swarup, G.; Chakrabarti, S.; Kaur, I.
10.1101/2024.07.08.601678 — genomics — Posted on 2024-07-09
3813 Physiologically refined cell culture conditions uncover oncogene-dependent metabolic signatures in Ewing sarcoma spheroids
Ceranski, A. K.; Carreno-Gonzalez, M. J.; Ehlers, A. C.; Kolodynska, Z.; Vinca, E.; Faehling, T.; Hanssen, K. M.; Poeller, P.; Ohmura, S.; Cidre-Aranaz, F.; Schulze, A.; Gruenewald, T. G. P.
10.1101/2024.07.05.602211 — cancer biology — Posted on 2024-07-09
3815 A microvascularized in vitro liver model for disease modeling and drug discovery
Bonanini, F.; Dinkelberg, R.; Torregrosa, M. C.; Kortekaas, N.; Hagens, T. M. S.; Treillard, S.; Kurek, D.; van Duinen, V.; Vulto, P.; Bircsak, K.
10.1101/2024.07.05.602196 — bioengineering — Posted on 2024-07-09
3817 Clathrin-associated carriers enable recycling through a kiss-and-run mechanism
Xu, J.; Liang, Y.; Li, N.; Dang, S.; Jiang, A.; Liu, Y.; Guo, Y.; Yang, X.; Yuan, Y.; Zhang, X.; Yang, Y.; Du, Y.; Shi, A.; Liu, X.; Li, D.; He, K.
10.1101/2024.07.09.601372 — cell biology — Posted on 2024-07-09
3822 Potato cultivars use different root physiological and molecular mechanisms to acclimate to salt stress
Nicolas, M.; Bouma, J.; Venema, J. H.; Van der Schoot, H.; Verstappen, F.; De Zeeuw, T.; Langedijk, S. E.; Boer, D.; Bucher, J.; Staal, M.; Krom, B.; Elzenga, J. T. M.; Visser, R.; Testerink, C.; Karlova, R.
10.1101/2024.07.05.602205 — plant biology — Posted on 2024-07-09
3823 Airway smooth muscle tone curbs hyperresponsiveness in experimental asthma
Gazzola, M.; Boucher, M.; Henry, C.; Rojas-Ruiz, A.; Marsolais, D.; Bosse, Y.
10.1101/2024.07.05.602208 — physiology — Posted on 2024-07-09
3824 Modeling Immunoglobulin light chain amyloidosis in Caenorhabditis elegans
Romeo, M.; Barzago, M. M.; Corbelli, A.; Maglioni, S.; Ventura, N.; Natale, C.; Conz, A.; Salmona, M.; Palladini, G.; Nuvolone, M.; Fiordaliso, F.; Merlini, G.; Diomede, L.
10.1101/2024.07.05.602215 — pathology — Posted on 2024-07-09
3826 Uncertainty-Aware Traction Force Microscopy
Kandasamy, A.; Yeh, Y.-T.; Serrano, R.; Mercola, M.; del Alamo, J. C.
10.1101/2024.07.05.602172 — biophysics — Posted on 2024-07-09
3827 VirID: Beyond Virus Discovery - An Integrated Platform for Comprehensive RNA Virus Characterization
Yang, Z.; Shan, Y.; Liu, X.; Chen, G.; Pan, Y.; Gou, Q.; Zou, J.; Chang, Z.; Zeng, Q.; Yang, C.; Kong, J.; Sun, Y.; Li, S.; Zhang, X.; Wu, W.; Li, C.; Peng, H.; Holmes, E. C.; Guo, D.; Shi, M.
10.1101/2024.07.05.602175 — bioinformatics — Posted on 2024-07-09
3831 Somatic Cell Identity Affects Specific Cell Differentiation Programs Upon Reprogramming In Vivo
Zikmund, T.; Fiorentino, J.; Penfold, C. A.; Stock, M.; Agarwal, G.; Langfeld, L.; Hamperl, S.; Scialdone, A.; Hoermanseder, E.
10.1101/2024.07.05.602198 — developmental biology — Posted on 2024-07-09
3832 LAG-3 blockade reactivates the CD8+ T cell expansion program to re-expand contracted clones in the tumor
Takahashi, M.; Tsunoda, M.; Aoki, H.; Kurosu, M.; Ogiwara, H.; Shichino, S.; Bending, D.; Ishikawa, S.; Thaventhiran, J.; Matsushima, K.; Ueha, S.
10.1101/2024.07.05.601623 — immunology — Posted on 2024-07-09
3833 Tau phosphorylation suppresses oxidative stress-induced mitophagy via FKBP8 receptor modulation
Isei, M. O.; Crockett, M.; Chen, E.; Rodwell-Bullock, J.; Caroll, T.; Girardi, P. A.; Nehrke, K.; Johnson, G. V.
10.1101/2024.07.05.602170 — neuroscience — Posted on 2024-07-09
3834 Pharmacological rescue of motor circuit dysfunction in a Drosophila model of paroxysmal dyskinesia
Wilson, A.; Jiang, Y.; Desai, N.; Simon-Batsford, N.; Sanderson, A.; Tolley, I.; Gao, H.; Jepson, J.
10.1101/2024.07.05.602188 — neuroscience — Posted on 2024-07-09
3835 Frontal Theta Oscillations and Cognitive Flexibility: Age-Related Modulations in EEG Activity
Darna, M.; Stolz, C.; Jauch, H. S.; Strumpf, H.; Hopf, J. M.; Seidenbecher, C. I.; Schott, B. H.; Richter, A.
10.1101/2024.07.05.602082 — neuroscience — Posted on 2024-07-09
3837 Tabula Glycine: The whole-soybean single-cell resolution transcriptome atlas
Cervantes-Perez, S. A.; Thibivilliers, S.; Amini, S.; Pelletier, J. M.; Meyer, I.; Xu, H.; Tennant, S.; Ma, P.; Sprueill, C. M.; Farmer, A. D.; Coate, J.; Nelissen, H.; Yao, Q.; Martin, O.; Amezquita, E. J.; Goldberg, R.; Harada, J.; Libault, M.
10.1101/2024.07.08.602332 — plant biology — Posted on 2024-07-09
3838 Exercise and disease state influence the beneficial effects of Fn14-depletion on survival and muscle pathology in the SOD1G93A amyotrophic lateral sclerosis (ALS) mouse model
Hazell, G.; Ahlskog, N.; Sutton, E. R.; Okoh, M.; Hoolachan, J. M.; Scaife, T.; Iqbal, S.; McCallion, E.; Bhomra, A.; Kordala, A. J.; Scamps, F.; Raoul, C.; Wood, M. J.; Bowerman, M.
10.1101/2024.07.05.602199 — pathology — Posted on 2024-07-09
3840 Reconstructing the evolutionary history of freshwater fishes (Nemacheilidae) across Eurasia since early Eocene
Bohlen, V. S.; Dvorak, T.; Freyhof, J.; Kottelat, M.; Levin, B.; Golubtsov, A.; Slechta, V.; Bohlen, J.
10.1101/2024.07.05.602185 — evolutionary biology — Posted on 2024-07-09
3841 Selective promotion of oligonucleotides in the course of evolution
Mathew, B.; Halder, A.; Panda, S.; Jaiswal, N.; Pramanik, D.; Peela, S. C. M.; Garg, A.; Tripathi, S.; Gupta, P.; Malhotra, V.; Ahuja, G.; Sengupta, D.
10.1101/2024.07.05.602168 — evolutionary biology — Posted on 2024-07-09
3843 Physiological Roles of an Acinetobacter-specific σ Factor
Bacon, E. E.; Myers, K. S.; Iruegas-Lopez, R.; Banta, A. B.; Place, M.; Ebersberger, I.; Peters, J. M.
10.1101/2024.07.08.602572 — microbiology — Posted on 2024-07-09
3845 Structurally targeted mutagenesis identifies key residues supporting α-synuclein misfolding in multiple system atrophy
Reis, P. M.; Holec, S. A. M.; Ezeiruaku, C.; Frost, M. P.; Brown, C. K.; Liu, S. L.; Olson, S. H.; Woerman, A. L.
10.1101/2024.07.04.602104 — neuroscience — Posted on 2024-07-09
3847 Humans forage for reward in reinforcement learning tasks
Zid, M.; Laurie, V.-J.; Levine-Champagne, A.; Shourkeshti, A.; Harrel, D.; Herman, A.; Ebitz, B.
10.1101/2024.07.08.602539 — neuroscience — Posted on 2024-07-08
3850 Cerebellar output neurons impair non-motor behaviors by altering development of extracerebellar connectivity
Lee, A. S.; Arefin, T. M.; Gubanova, A.; Stephen, D.; Liu, Y.; Lao, Z.; Krishnamurthy, A.; De Marco Garcia, N. V.; Heck, D. H.; Zhang, J.; Rajadhyaksha, A. M.; Joyner, A. L.
10.1101/2024.07.08.602496 — neuroscience — Posted on 2024-07-08
3851 Pre-cancerous Niche Remodelling Dictates Nascent Tumour Survival
Skrupskelyte, G.; Rojo Arias, J. E.; Dang, Y.; Han, S.; Bejar, M. T.; Colom, B.; Fowler, J. C.; Jones, P.; Rulands, S.; Simons, B. D.; Alcolea, M.
10.1101/2024.07.04.602022 — cancer biology — Posted on 2024-07-08
3853 Promoting enzyme catalysis via azobenzene facilitated vibrational energy transfer
Lahmy, R.; Hiefinger, C.; Zeqiri, F.; Mandl, S.; Straub, K.; Stockerl, W.; Gschwind, R. M.; Rudack, T.; Koenig, B.; Hupfeld, A.
10.1101/2024.07.04.602025 — biophysics — Posted on 2024-07-08
3854 Transcriptional landscapes underlying Notch-induced lineageconversion and plasticity of mammary basal cells
Merle, C.; Rodrigues, C.; Pourkhalili Langeroudi, A.; Journot, R.; Rost, F.; Dang, Y.; Rulands, S.; Fre, S.
10.1101/2024.07.04.602034 — developmental biology — Posted on 2024-07-08
3857 Glioma-associated tertiary lymphoid structures are sites of lymphocyte clonal expansion and plasma cell formation
Cakmak, P.; Lun, J. H.; Singh, A.; Macas, J.; Schupp, J.; Koehler, M.; Starzetz, T.; Burger, M. C.; Steidl, E.; Hasse, L. M.; Hattingen, E.; Plate, K. H.; Reiss, Y.; Imkeller, K.
10.1101/2024.07.04.602038 — immunology — Posted on 2024-07-08
3858 Photopharmacological activation of adenosine A1receptor signaling suppresses seizures in a mousemodel for temporal lobe epilepsy
Spanoghe, J.; Boon, P.; Vergaelen, M.; De Colvenaer, M.; Mariman, T.; Vonck, K.; Carrette, E.; Wadman, W.; Craey, E.; Larsen, L. E.; Sprengers, M.; Missinne, J.; Van Calenbergh, S.; De Bundel, D.; Smolders, I.; Raedt, R.
10.1101/2024.07.04.602052 — neuroscience — Posted on 2024-07-08
3859 Calcium-triggered (de)ubiquitination events in synapses
Ainatzi, S.; Kaufmann, S. V.; Silbern, I.; Georgiev, S. V.; Lorenz, S.; Rizzoli, S. O.; Urlaub, H.
10.1101/2024.07.04.602026 — neuroscience — Posted on 2024-07-08
3861 Intracellular Protein Editing to Enable Incorporation of Non-Canonical Residues into Endogenous Proteins
Beyer, J.; Serebrenik, Y.; Toy, K.; Najar, M. A.; Raniszewski, N.; Shalem, O.; Burslem, G.
10.1101/2024.07.08.602493 — biochemistry — Posted on 2024-07-08
3862 Discovery and pharmacological characterization of nanobodies acting as potent positive allosteric modulators of the calcium-sensing receptor
Mos, I.; Zögg, T.; Wohlkönig, A.; Egholm, A. M. H.; Rahman, S. N.; Pardon, E.; Steyaert, J.; Bräuner-Osborne, H.; Mathiesen, J. M.
10.1101/2024.07.08.602375 — biochemistry — Posted on 2024-07-08
3867 Genetic architecture of the tomato fruit lipidome; new insights link lipid and volatile compounds
Kuhalskaya, A.; Li, X.; Lee, J.; Gonda, I.; Nauen, J.; Bulut, M.; Karakas, E.; Fisher, J.; Kraemer, K.; Vanholme, R.; Rosental, L.; Wijesingha Ahchige, M.; Garbowicz, K.; Klemmer, A.; Russ, A.-K.; Donath, A.; Cuadros-Inostroza, A.; Boerjan, W.; Tieman, D.; Zamir, D.; Klee, H.; Alseekh, S.
10.1101/2024.07.08.602461 — molecular biology — Posted on 2024-07-08
3868 Chromatin endogenous cleavage provides a global view of RNA polymerase II transcription kinetics
VanBelzen, J.; Sakelaris, B.; Brickner, D. G.; Marcou, N.; Riecke, H.; Mangan, N.; Brickner, J. H.
10.1101/2024.07.08.602535 — molecular biology — Posted on 2024-07-08
3872 Asparagine couples group A Streptococcal metabolism to virulence
Sharma, A.; Anand, A.; Ravins, M.; Horstmann, N. M. M.; McIver, K. S.; Hanski, E.
10.1101/2024.07.08.602371 — microbiology — Posted on 2024-07-08
3873 A pumpless and tubeless microfluidic device enables extended in vitro development of Cryptosporidium parvum
Gunasekera, S.; Thierry, B.; Cheah, E.; King, B.; Monis, P.; Carr, J. M.; Chopra, A.; Watson, M.; O'Dea, M.; Ryan, U.
10.1101/2024.07.07.602413 — microbiology — Posted on 2024-07-08
3875 Nematode Extracellular Protein Interactome Expands Connections between Signaling Pathways
Nawrocka, W. I.; Cheng, S.; Hao, B.; Rosen, M.; Cortes, E.; Baltrusaitis, E.; Aziz, Z.; Kovacs, I. A.; Özkan, E.
10.1101/2024.07.08.602367 — biochemistry — Posted on 2024-07-08
3876 Jasmonic acid signalling is targeted by a smut fungal Tin2-fold effector
Gul, S.; Mendoza-Rojas, G.; Hessler, N.; Galle, S.; Smits, S. H. J.; Altegoer, F.; Gohre, V.
10.1101/2024.07.08.602457 — biochemistry — Posted on 2024-07-08
3879 Decoding the Escherichia coli epitranscriptome
Riquelme-Barrios, S.; Vasquez Camus, L.; Cusack, S. A.; Burdack, K.; Plamenov Petrov, D.; Yesiltac, G. N.; Kaiser, S.; Giehr, P.; Jung, K.
10.1101/2024.07.08.602490 — microbiology — Posted on 2024-07-08
3881 Biological tick control: modeling the potential impact of entomopathogenic fungi on the transmission of East Coast fever in cattle
Oundo, J. W.; Hartemink, N.; de Jong, M. C. M.; Koenraadt, C. J. M.; Kalayou, S.; Masiga, D.; ten Bosch, Q.
10.1101/2024.07.08.602534 — microbiology — Posted on 2024-07-08
3882 FapR regulates HssRS-mediated heme homeostasis in Bacillus anthracis
Skaar, E. P.; Pi, H.; Carlin, S. M.; Beavers, W. N.; Hillebrand, G. H.; Krystofiak, E. S.; Stauff, D. L.
10.1101/2024.07.08.602573 — microbiology — Posted on 2024-07-08
3883 MICROBIOTA AT THE CROSS ROAD OF DIET AND HEALTH: HOW DIETARY FATS SHAPE BACTERIAL LAND-SCAPE AND INFLUENCE GLOBAL HEALTH
Portela, N. D.; Eberhardt, N.; Bergero, G.; Mazzocco, Y. L.; Aoki, M. P.; Galvan, C. A.; Cano, R. C.; Pesoa, S. A.
10.1101/2024.07.08.602483 — microbiology — Posted on 2024-07-08
3886 Subsurface Microbial Colonization at Mineral-Filled Veins in 2-Billion-Year-Old Igneous Rock from the Bushveld Complex, South Africa
Suzuki, Y.; Webb, S. J.; Kouduka, M.; Kobayashi, H.; Castillo, J. H.; Kallmeyer, J.; Moganedi, K.; Allwright, A. J.; Klemd, R.; Roelofse, F.; Mapiloko, M.; Hill, S. J.; Ashwal, L. D.; Trumbull, R. B.
10.1101/2024.07.08.602455 — microbiology — Posted on 2024-07-08
3887 Typing of feces-derived Candida albicans strains using a novel seven-locus microsatellite panel reveals associations with yeast phenotype in individuals with inflammatory bowel disease
van Thiel, I. A. M.; Kreulen, I. A. M.; Benard, M. V.; de Goffau, M.; Theelen, B.; Heinsbroek, S. E. M.; Zylka, P.; Ponsioen, C. Y.; Boekhout, T.; de Jonge, W. J.; Rosendahl, S.; van den Wijngaard, R. M.; Hagen, F.
10.1101/2024.07.08.601751 — microbiology — Posted on 2024-07-08
3888 EM-Compressor: Electron Microscopy Image Compression in Connectomics with Variational Autoencoders
Li, Y.; Park, C. F.; Xenes, D.; Bishop, C.; Berger, D. R.; Samuel, A. D. T.; Wester, B.; Lichtman, J. W.; Pfister, H.; Li, W.; Meirovitch, Y.
10.1101/2024.07.07.601368 — neuroscience — Posted on 2024-07-08
3889 Astroglial atrophy associates with loss of nuclear S100A10 in the hippocampus of aged male tree shrews
Rodriguez-Callejas, J. d. D.; Irene-Fierro, M.; Aguilar-Navarro, S. G.; Fuchs, E.; Perez-Cruz, C.
10.1101/2024.07.04.602113 — neuroscience — Posted on 2024-07-08
3890 Structural insights into the in situ assembly of clustered protocadherin γB4
Zhang, Z.; Chen, F.; Zhang, Z.; Guo, L.; Feng, T.; Fang, Z.; Xin, L.; Yu, Y.; Hu, H.; He, Y.
10.1101/2024.07.05.602218 — biophysics — Posted on 2024-07-08
3892 DNA walk of specific fused oncogenes exhibit distinct fractal geometric characteristics in nucleotide patterns
Das, A.; Sehgal, M.; Singh, A.; Goyal, R.; Prabhakar, M.; Fricke, J.; Mambetsariev, I.; Kulkarni, P.; Jolly, M. K.; Salgia, R.
10.1101/2024.07.05.602166 — bioinformatics — Posted on 2024-07-08
3893 Activation of two noncanonical R proteins by an insect effector confers plant immunity to aphid infestation
Lei, K.; Tian, D.; Shao, Y.; Wang, F.; Chang, J.; Char, S. N.; Li, G.; Dong, Z.; Zhang, J.; Cui, J.-H.; Zhao, S.; Li, J.; Liu, H.; Liu, G.-Q.; Lv, P.; Wei, M.; Jin, X.; Song, Q.; Yang, B.; Zhang, K.; Wu, D.; Wang, D. W.
10.1101/2024.07.06.601796 — genetics — Posted on 2024-07-08
3894 Independent genetic mapping experiments identify diverse molecular determinants of host adaptation in a generalist herbivore
Villacis-Perez, E.; De Graeve, F.; De Beer, B.; Ali Alshami, S.; de Jong, R.; De Meyer, T.; Van Leeuwen, T.
10.1101/2024.07.05.602111 — evolutionary biology — Posted on 2024-07-08
3895 Abundance, diversity and evolution of tyrosinase enzymes involved in the adhesive systems of mussels and tubeworms
Duthoo, E.; Delroisse, J.; Maldonado, B.; Sinot, F.; Mascolo, C.; Wattiez, R.; Lopez, P. J.; Van de Weerdt, C.; Harrington, M.; Flammang, P.
10.1101/2024.07.05.602216 — evolutionary biology — Posted on 2024-07-08
3896 Fish predation induces drifting and emergence in an experimental stream mesocosm system
Vermiert, A.-M.; Madge Pimentel, I.; Rehsen, P. M.; Meisner, J.; Horstmann, M.; Beermann, A. J.; Leese, F.; Weiss, L. C.; Tollrian, R.
10.1101/2024.07.04.602120 — ecology — Posted on 2024-07-08
3899 Inclusion of Salicornia ramosissima biomass in diets for juvenile whiteleg shrimp (Penaeus vannamei) induces favourable but transient effects in the immune and oxidative status
Ramos-Pinto, L.; Marcal, R.; Barreto, A.; Laranjeira, A.; Machado, M.; Fernandez-Boo, S.; Teixeira, C.; Couto, A.; Dias, J.; Guilherme, S.; Verissimo, A.; Pinto, D.; Rocha, R.; Costas, B.
10.1101/2024.07.05.602095 — immunology — Posted on 2024-07-08
3900 eLemur: A cellular-resolution 3D atlas of the mouse lemur brain
Jeon, H.; Kim, J.; Kim, J.; Choi, Y. K.; Ho, A. C. L.; Pifferi, F.; Huber, D.; Feng, L.; Kim, J.
10.1101/2024.07.05.601641 — neuroscience — Posted on 2024-07-08
3901 Mutation of phosphatidate phosphohydrolase genes confers broad-spectrum disease resistance in plants
Gong, Q.; Sha, G.; Han, X.; Guo, Z.; Yang, L.; Yang, W.; Tan, R.; Chen, G.; Li, Y.; Shen, X.; Xie, K.; Cai, G.; Hu, H.; Luo, J.; Li, Q.; Li, G.
10.1101/2024.07.04.602136 — plant biology — Posted on 2024-07-08
3904 stormTB: A web-based simulator of a murine minimal-PBPK model for anti-tuberculosis treatments.
Visintainer, R.; Fochesato, A.; Boaretti, D.; Giampiccolo, S.; Watson, S.; Levi, M.; Reali, F.; Marchetti, L.
10.1101/2024.07.04.602069 — pharmacology and toxicology — Posted on 2024-07-08
3905 Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets
Vijay, V.; Karisani, N.; Shi, L.; Hung, Y.-H.; Vu, P.; Kattel, P.; Kenney, L.; Merritt, J.; Adil, R.; Wu, Q.; Zhen, Y.; Morris, R.; Kreuzer, J.; Kathiresan, M.; Herrera Lopez, X. I.; Ellis, H.; Gritti, I.; Lecorgne, L.; Farag, I.; Popa, A.; Shen, W.; Kato, H.; Xu, Q.; Balasooriya, E. R.; Wu, M.-J.; Chaturantabut, S.; Kelley, R. K.; Cleary, J. M.; Lawrence, M. S.; Root, D. E.; Benes, C. H.; Deshpande, V.; Juric, D.; Ferrone, C. R.; Sellers, W. R.; Haas, W.; Vazquez, F.; Getz, G.; Bardeesy, N.
10.1101/2024.07.04.601970 — cancer biology — Posted on 2024-07-08
3907 Reinforcement learning guides single-cell sequencing in decoding lineage and cell fate decisions
Fu, Z.; Wang, S.; Sun, K.; Xu, B.; Ye, X.; Wen, Z.; Shen, M.; Chen, M.; Chen, F.; Xu, Y.; Chen, S.; Wang, J.
10.1101/2024.07.04.602019 — bioinformatics — Posted on 2024-07-08
3908 Regulation of cell-nanoparticle interactions through mechanobiology
Cassani, M.; Niro, F.; Fernandes, S.; Pereira-Sousa, D.; Morazzo, S.; Durikova, H.; Vrbsky, J.; Oliver-De La Cruz, J.; Klimovic, S.; Pribyl, J.; Loja, T.; Skladal, P.; Caruso, F.; Forte, G.
10.1101/2024.07.07.599665 — bioengineering — Posted on 2024-07-08
3909 Droplet-AI-empowered high-throughput screening of cell-free gene expression
Zhu, J.; Meng, Y.; Gao, W.; Yang, S.; Zhu, W.; Ji, X.; Zhai, X.; Liu, W.; Luo, Y.; Ling, S.; Li, J.; Liu, Y.
10.1101/2024.07.04.602084 — bioengineering — Posted on 2024-07-08
3911 NSP4 mutation T492I drives rapid evolution of SARS-CoV-2 toward Omicron
Lin, X.; Sha, Z.; Zhang, C.; Adler, J. M.; Vidal, R. M.; Langner, C.; Fu, B.; Xiong, Y.; Tan, M.; Jiang, C.; Zeng, H.; Zhang, X.; Li, Q.; Yan, J.; Lu, X.; Wang, S.; Mao, X.; Kunec, D.; Trimpert, J.; Wu, H.; Zou, Q.; Zhu, Z.
10.1101/2024.07.05.602217 — evolutionary biology — Posted on 2024-07-08
3913 White matter microglia morphological changes with aging in guinea pig offspring born growth restricted
Nunes, T. B.; Nygard, K. L.; Courchesne, M. C. J.; Whitehead, S. N.; Richardson, B. S.; Regnault, T. R. H.
10.1101/2024.07.04.602101 — developmental biology — Posted on 2024-07-08
3914 Early 2022 breakthrough infection sera from India target the conserved cryptic class 5 epitope to counteract immune escape by SARS-CoV-2 variants
Das Jana, I.; Kanjo, K.; Roy, S.; Bhasin, M.; Bhattacharya, S.; Banerjee, I.; Jana, S.; Chatterjee, A.; Chakraborty, A.; Chakraborty, S.; Mukherjee, B.; Varadarajan, R.; Mondal, A.
10.1101/2024.07.08.602485 — molecular biology — Posted on 2024-07-08
3917 Microglial low-affinity FcγR mediates the phagocytic elimination of dopaminergic neurons in Parkinsons disease degeneration
Casanova, P. V.; Saavedra-Lopez, E.; Freitag-Berenguel, I.; Usandizaga, M.; Martinez-Remedios, P.; Gimenez-Montes, C.; Clinton, E.; Roig-Martinez, M.; Cribaro, G. P.; Barcia, C.
10.1101/2024.07.04.602092 — neuroscience — Posted on 2024-07-08
3918 Time-resolved functional connectivity during visuomotor graph learning
Loman, S.; Caciagli, L.; Kahn, A. E.; Szymula, K. P.; Nyema, N.; Bassett, D. S.
10.1101/2024.07.04.602005 — neuroscience — Posted on 2024-07-08
3920 Characterizing BOLD activation patterns in the human hippocampus with laminar fMRI
Pfaffenrot, V.; Bouyeure, A.; Gomes, C. A.; Kashyap, S.; Axmacher, N.; Norris, D.
10.1101/2024.07.04.602065 — neuroscience — Posted on 2024-07-08
3921 The dynamic gene regulatory landscape of the mouse brain in response to sleep deprivation
Jagannath, A.; Bafna, A.; Dang, Q.; Taylor, L.; Walsh, S.; Sims, D.; George, C.
10.1101/2024.07.04.602083 — neuroscience — Posted on 2024-07-08
3922 MJF-14 proximity ligation assay detects early non-inclusion alpha-synuclein pathology with enhanced specificity and sensitivity
Jensen, N. M.; Fu, Y.; Betzer, C.; Li, H.; Elfarrash, S.; Shaib, A. H.; Krah, D.; Vitic, Z.; Reimer, L.; Gram, H.; Buchman, V.; Denham, M.; Rizzoli, S. O.; Halliday, G. M.; Jensen, P. H.
10.1101/2024.07.08.602186 — neuroscience — Posted on 2024-07-08
3925 Characterization of the Cannabis sativa glandular trichome epigenome
Conneely, L. J.; Hurgobin, B.; Ng, S.; Tamiru-Oli, M.; Lewsey, M. G.
10.1101/2024.07.04.602151 — plant biology — Posted on 2024-07-08
3927 Chronic inorganic nitrate supplementation does not improve metabolic health and worsens disease progression in mice with diet-induced obesity.
Sowton, A. P.; Holzner, L. M.; Krause, F. N.; Baxter, R.; Mocciaro, G.; Krzyzanska, D. K.; Minnion, M.; O'Brien, K. A.; Harrop, M. C.; Darwin, P. M.; Thackray, B. D.; Vacca, M.; Feelisch, M.; Griffin, J. L.; Murray, A. J.
10.1101/2024.07.04.602070 — physiology — Posted on 2024-07-08
3928 Antimicrobial cetylpyridinium chloride suppresses mast cell function by targeting tyrosine phosphorylation of Syk kinase
Obeng, B.; Bennett, L. J.; West, B. E.; Wagner, D. J.; Fleming, P. J.; Tasker, M. N.; Lorenger, M. K.; Smith, D. R.; Systuk, T.; Plummer, S. M.; Eom, J.; Paine, M. D.; Frangos, C. T.; Wilczek, M. P.; Shim, J. K.; Maginnis, M. S.; Gosse, J. A.
10.1101/2024.07.04.602096 — pharmacology and toxicology — Posted on 2024-07-08
3931 Developing peptide-based fusion inhibitors as an antiviral strategy utilizing Coronin 1 as a template
Panda, M. S.; Qazi, B.; Vishwakarma, V.; Pattnaik, G. P.; Haldar, S.; Chakraborty, H.
10.1101/2024.07.04.602150 — biophysics — Posted on 2024-07-08
3933 Heli-SMACC: Helicase-targeting SMAll Molecule Compound Collection
Martin, H.-J.; Hossain, M. A.; Wellnitz, J.; Kelestemur, E.; Hochuli, J.; Perveen, S.; Arrowsmith, C.; Willson, T. M.; Muratov, E.; Tropsha, A.
10.1101/2024.07.04.602122 — bioinformatics — Posted on 2024-07-08
3934 Exploring Effector Protein Dynamics and Natural Fungicidal Potential in Rice Blast Pathogen Magnaporthe oryzae
Ferdausi, J.; Robin, T. B.; Nasrin, S.; Ahmed, I.; Hossain, T.; Hasan, M. M.; Soaeb, M. H.; Tamim, M. A.; Yeasmin, N. J.; Habiba, U.; Ahmed, N.; Rani, N. A.; Bhuyian, M. S.; Vakare, S. N.; Moin, A. T.; Patil, R. B.; Hossain, M. S.
10.1101/2024.07.04.602162 — bioinformatics — Posted on 2024-07-08
3936 Engineering of Transmembrane Alkane Monooxygenases to Improve a Key Reaction Step in the Synthesis of Polymer Precursor Tulipalin A
Kourist, R.; Nigl, A.; Delsoglio, V.; Grgic, M.; Malihan-Yap, L.; Myrtollari, K.; Spasic, J.; Winkler, M.; Oberdorfer, G.; Taden, A.; Anic, I.
10.1101/2024.07.04.601532 — bioengineering — Posted on 2024-07-08
3939 Behavioral and neural correlates of social hierarchy formation in a sex-changing fish
Quertermous, H. M.; Kamstra, K.; van der Burg, C. A.; Muncaster, S.; Todd, E. V.; Brown, C.; Gemmell, N. J.
10.1101/2024.07.04.602141 — animal behavior and cognition — Posted on 2024-07-08
3942 Functional traits explain growth resistance to successive hotter droughts across a wide set of common and future tree species in Europe
Kretz, L.; Schnabel, F.; Richter, R.; Raabgrund, A.; Kattge, J.; Andraczek, K.; Kahl, A.; Kuenne, T.; Wirth, C.
10.1101/2024.07.04.602057 — ecology — Posted on 2024-07-08
3948 Acidic pH attenuates immune killing through inactivation of perforin
Hodel, A. W.; Rudd-Schmidt, J. A.; Noori, T.; Lupton, C. J.; Cheuk, V. C.; Trapani, J. A.; Hoogenboom, B.; Voskoboinik, I.
10.1101/2024.07.04.602105 — immunology — Posted on 2024-07-08
3950 The perineurium integrates leptin with its sympathetic outflow to protect against obesity
Sarker, G.; Haberman, E.; Chandran, A.; Monfeuga, T.; Maroteau, C.; Lundh, S.; Raimondi, A.; Martinez Sanchez, N.; Arus, B.; Iannacone, M.; Toledo, E. M.; Domingos, A.
10.1101/2024.07.04.602091 — neuroscience — Posted on 2024-07-08
3952 Hedgehog-Hippo pathway interactions promote T cell exclusion from the tumor microenvironment in basal cell carcinoma
Stockmaier, G.; Varkhande, S.; Krenn, P. W.; Dang, H.-h.; Sharma, A.; Elmer, D. P.; Steiner, M.; Zaborsky, N.; Neureiter, D.; Greil, R.; Horejs-Hoeck, J.; Fortelny, N.; Gratz, I. K.; Aberger, F.
10.1101/2024.07.07.602398 — cancer biology — Posted on 2024-07-08
3955 Structural basis for Vipp1 membrane binding: From loose coats and carpetsto ring and rod assemblies
Junglas, B.; Kartte, D.; Kutzner, M.; Hellmann, N.; Ritter, I.; Schneider, D.; Sachse, C.; Sachse, C.
10.1101/2024.07.08.602470 — biophysics — Posted on 2024-07-08
3956 MINFLUX fluorescence nanoscopy in biological tissue
Moosmayer, T.; Kiszka, K. A.; Westphal, V.; Pape, J. K.; Leutenegger, M.; Steffens, H.; Grant, S. G. N.; Sahl, S. J.; Hell, S. W.
10.1101/2024.07.06.602333 — biophysics — Posted on 2024-07-08
3957 Structural plasticity of bacterial ESCRT-III protein PspA in higher-orderassemblies
Junglas, B.; Hudina, E.; Schoennenbeck, P.; Ritter, I.; Heddier, A.; Santiago-Schuebel, B.; Huesgen, P. F.; Schneider, D.; Sachse, C.
10.1101/2024.07.08.602472 — biophysics — Posted on 2024-07-08
3960 Azole resistance: Patterns of amino acid substitutions in Candida sterol 14α-demethylase
Rao, R. S. P.; Pinto, L.; Shastry, R. P.; Dakal, T. C.; Suravajhala, P.; Sashindran, V.; Ghate, S.
10.1101/2024.07.04.602050 — bioinformatics — Posted on 2024-07-08
3961 Activity of FoxP2-positive neurons correlate with tadpole begging behavior
Ludington, S. C.; McKinney, J. E.; Butler, J. M.; Goolsby, B. C.; Callan, A. A.; Gaines-Richardson, M.; O'Connell, L. A.
10.1101/2023.05.26.542531 — animal behavior and cognition — Posted on 2024-07-08
3962 The Pgb1 locus controls glycogen aggregation in astrocytes of the aged hippocampus without impacting cognitive function
Gomez-Pascual, A.; Glikman, D. M.; Ng, H. X.; Tomkins, J. E.; Lu, L.; Xu, Y.; Ashbrook, D. G.; Kaczorowski, C.; Kempermann, G.; Killmar, J.; Mozhui, K.; Ohlenschlaeger, O.; Aebersold, R.; Ingram, D. K.; Williams, E. G.; Williams, R. W.; Overall, R. W.; Jucker, M.; de Bakker, D. E. M.
10.1101/2023.11.22.567373 — genetics — Posted on 2024-07-08
3964 Seasonal changes in fish eDNA signal vary between contrasting river types
Griffiths, N. P.; Bolland, J. D.; Wright, R. M.; Blabolil, P.; Macarthur, J. A.; Sellers, G. S.; Hänfling, B.
10.1101/2024.07.08.601838 — ecology — Posted on 2024-07-08
3967 SRSF2 transcriptional function maintains genome integrity during cell division
Wagner, R. E.; Arnetzl, L.; Britto-Borges, T.; Heit-Mondrzyk, A.; Bakr, A.; Sollier, E.; Panten, J.; Delaunay, S.; Sohn, D.; Schmezer, P.; Odom, D. T.; Mueller-Decker, K.; Plass, C.; Dieterich, C.; Lutsik, P.; Borneloev, S.; Frye, M.
10.1101/2024.07.08.602469 — cell biology — Posted on 2024-07-08
3969 Future movement plans interact in sequential arm movements
Kashefi, M.; Reschechtko, S.; Ariani, G.; Shahbazi, M.; Tan, A.; Diedrichsen, J.; Pruszynski, J. A.
10.1101/2023.05.24.542099 — neuroscience — Posted on 2024-07-08
3970 Developmental and age-related synapse elimination is mediated by glial Croquemort
Jay, T. R.; Kang, Y.; Ouellet-Massicotte, V.; Micael, M. K. B.; Kacouros-Perkins, V. L.; Chen, J.; Sheehan, A.; Freeman, M.
10.1101/2024.06.24.600214 — neuroscience — Posted on 2024-07-08
3971 Light-microscopy based dense connectomic reconstruction of mammalian brain tissue
Tavakoli, M. R.; Lyudchik, J.; Januszewski, M.; Vistunou, V.; Agudelo, N.; Vorlaufer, J.; Sommer, C.; Kreuzinger, C.; Oliveira, B.; Cenameri, A.; Novarino, G.; Jain, V.; Danzl, J. G.
10.1101/2024.03.01.582884 — neuroscience — Posted on 2024-07-08
3972 Miniscope Recording Calcium Signals at Hippocampus of Mice Navigating an Odor Plume
de Souza, F. S.; Williamson, R.; McCullough, C. M.; Teel, A.; Futia, G.; Ma, M.; True, A. C.; Crimaldi, J. P.; Gibson, E. A.; Restrepo, D.
10.1101/2024.06.12.598681 — neuroscience — Posted on 2024-07-08
3981 Synaptic plasticity in the medial preoptic area of male mice encodes social experiences with female and regulates behavior toward young
Ito, K.; Sato, K.; Tsuneoka, Y.; Maejima, T.; Okuno, H.; Hamasaki, Y.; Murakawa, S.; Takabayashi, Y.; Yoshihara, C.; Shindo, S.; Uki, H.; Herlitze, S.; Seki, M.; Suzuki, Y.; Sakurai, T.; Kuroda, K. O.; Minami, M.; AMANO, T.
10.1101/2023.10.23.560098 — zoology — Posted on 2024-07-08
3982 Cytokinin-inducible DIRIGENT13 involved in lignan synthesis and ROS accumulation promotes root growth and abiotic stress tolerance in Arabidopsis
Melnikava, A.; Perreau, F.; Paniagua, C.; Cheng, S.-C.; Huang, L.-M.; Ubogoeva, E.; Zemlyanskaya, E.; Yang, Y.-L.; Mouille, G.; Arnaud, D.; Hejatko, J.
10.1101/2024.06.25.600713 — plant biology — Posted on 2024-07-08
3983 Biochemical, biophysical, and structural investigations of two mutants (C154Y and R312H) of the human Kir2.1 channel involved in the Andersen-Tawil syndrome.
Zuniga, D.; Zoumpoulakis, A.; Veloso, R. F.; Peverini, L.; Shi, S.; Pozza, A.; Kugler, V.; Bonnete, F.; Bouceba, T.; Wagner, R.; Corringer, P.-J.; Fernandes, C. A.; Venien-Bryan, C.
10.1101/2024.02.09.579451 — biophysics — Posted on 2024-07-08
3984 On the pH-dependence of α-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation
Frey, L.; Ghosh, D.; Qureshi, B. M.; Rhyner, D.; Guerrero-Ferreira, R.; Pokharna, A.; Kwiatkowski, W.; Serdiuk, T.; Picotti, P.; Riek, R.; Greenwald, J.
10.1101/2023.06.25.546428 — biophysics — Posted on 2024-07-08
3985 Decoupling of the Onset of Anharmonicity between a Protein and Its Surface Water around 200 K
Zheng, L.; Zhou, B.; Wu, B.; Tan, Y.; Huang, J.; Tyagi, M.; Sakai, V. G.; Yamada, T.; O'Neill, H.; Zhang, Q.; Hong, L.
10.1101/2023.10.18.562890 — biophysics — Posted on 2024-07-08
3987 Quantitative Analysis of Miniature Synaptic Calcium Transients Using Positive Unlabeled Deep Learning
Beaupre, F.; Bilodeau, A.; Wiesner, T.; Leclerc, G.; Lemieux, M.; Nadeau, G.; Castonguay, K.; Fan, B.; Labrecque, S.; Hlozek, R.; De Koninck, P.; Gagne, C.; Lavoie-Cardinal, F.
10.1101/2024.07.04.602047 — bioinformatics — Posted on 2024-07-08
3992 Unexpectedly low recombination rates and presence of hotspots in termite genomes
Everitt, T.; Ronneburg, T.; Elsner, D.; Olsson, A.; Liu, Y.; Larva, T.; Korb, J.; Webster, M. T.
10.1101/2024.03.22.586269 — genomics — Posted on 2024-07-08
3994 Epigenetic regulation by TET1 in gene-environmental interactions influencing susceptibility to congenital malformations
van der Veer, B. K.; Chen, L.; Tsaniras, S. C.; Brangers, W.; Chen, Q.; Schroiff, M.; Custers, C.; Kwak, H. H. M.; Khoueiry, R.; Cabrera, R.; Gross, S. S.; Finnell, R. H.; Lei, Y.; Koh, K. P.
10.1101/2024.02.21.581196 — developmental biology — Posted on 2024-07-08
3995 Fully-Automated Multicolour Structured Illumination Module for Super-resolution Microscopy
Wang, H.; Brown, P. T.; Ullom, J.; Shepherd, D. P.; Heintzmann, R. P.; Diederich, B.
10.1101/2024.07.04.601961 — cell biology — Posted on 2024-07-08
3996 Cortistatin exerts an immunomodulatory and neuroprotective role in ischemic stroke
Castillo-Gonzalez, J.; Buscemi, L.; Vargas-Rodriguez, P.; Serrano-Martinez, I.; Forte-Lago, I.; Price-Hirt, M.; Hernandez-Cortes, P.; Hirt, L.; Gonzalez-Rey, E.
10.1101/2024.02.07.579281 — immunology — Posted on 2024-07-08
3997 The ciliary kinesin KIF7 controls the development of the cerebral cortex by acting differentially on SHH-signaling in dorsal and ventral forebrain
PEDRAZA, M.; GRAMPA, V.; SCOTTO-LOMASSESE, S.; PUECH, J.; MUZERELLE, A.; MOHAMMAD, A.; RENIER, N.; METIN, C.; MASSON, J.
10.1101/2024.03.21.586159 — neuroscience — Posted on 2024-07-08
3999 Neurocomputational Mechanisms Underlying Maladaptive Self-Belief Formation in Depression
Czekalla, N.; Schröder, A.; Mayer, A. V.; Stierand, J.; Stolz, D. S.; Kube, T.; Korn, C. W.; Wilhelm-Groch, I.; Klein, J. P.; Paulus, F. M.; Krach, S.; Müller-Pinzler, L.
10.1101/2024.05.09.593087 — neuroscience — Posted on 2024-07-08
4000 Metacognitive Experiences Track Rational Adaptations in Cognitive Processes
Vermeylen, L.; Braem, S.; Ivanchei, I. I.; Desender, K.; Gonzalez-Garcia, C.; Garcia-Roman, J. M.; Ruz, M.; Notebaert, W.
10.1101/2023.09.26.559523 — neuroscience — Posted on 2024-07-08
4001 A neurotrophin functioning with a Toll regulates structural plasticity in a dopaminergic circuit
SUN, J.; ROJO-CORTES, F. R.; ULIAN-BENITEZ, S.; FORERO, M. G.; LI, G.; SINGH, D.; WANG, X.; CACHERO, S.; MOREIRA, M.; KAVANAGH, D.; JEFFERIS, G. S. X. E.; CROSET, V.; HIDALGO, A.
10.1101/2023.01.04.522695 — neuroscience — Posted on 2024-07-08
4002 A theoretical basis for cell death
Himeoka, Y.; Horiguchi, S. A.; Kobayashi, T. J.
10.1101/2024.03.04.583348 — systems biology — Posted on 2024-07-08
4003 Proteomic and functional comparison between human induced and embryonic stem cells
Brenes, A. J.; Griesser, E.; Sinclair, L. V.; Davidson, L.; Prescott, A. R.; Singh, F.; Hogg, E. K. J.; Espejo-Serrano, C.; Jiang, H.; Yoshikawa, H.; Platani, M.; Swedlow, J.; Cantrell, D. A.; Lamond, A. I.
10.1101/2021.10.20.464767 — systems biology — Posted on 2024-07-08
4004 Novel endogenous engineering platform for robust loading and delivery of functional mRNA by extracellular vesicles
Zickler, A. M.; Liang, X.; Gupta, D.; Mamand, D.; de Luca, M.; Corso, G.; Errichelli, L.; Hean, J.; Sen, T.; Elsharkasy, O. M.; Kamei, N.; Niu, Z.; Zhou, G.; Zhou, H.; Roudi, S.; Wiklander, O. P. B.; Goergens, A.; Nordin, J.; Castilla-Llorente, V.; EL Andaloussi, S.
10.1101/2023.03.17.533081 — bioengineering — Posted on 2024-07-08
4005 Blood metabolomic profiling reveals new targets in the management of psychological symptoms associated with severe alcohol use disorder
Leclercq, S.; Ahmed, H.; Amadieu, C.; Petit, G.; Koistinen, V.; Leyrolle, Q.; Poncin, M.; Stärkel, P.; Kok, E.; Karhunen, P. J.; de Timary, P.; Laye, S.; Neyrinck, A. M.; Kärkkäinen, O. K.; Hanhineva, K.; Delzenne, N.
10.1101/2024.02.27.582239 — neuroscience — Posted on 2024-07-08
4007 Decoding Missense Variants by Incorporating Phase Separation via Machine Learning
Feng, M.; Wei, X.; Zheng, X.; Liu, L.; Lin, L.; Xia, M.; He, G.; Shi, Y.; Lu, Q.
10.1101/2024.04.01.587546 — bioinformatics — Posted on 2024-07-08
4008 Transposable element expression with variation in sex chromosome number: insights into a toxic Y effect on human longevity
Teoli, J.; Merenciano, M.; Fablet, M.; Necsulea, A.; Siqueira-de-Oliveira, D.; Brandulas-Cammarata, A.; Labalme, A.; Lejeune, H.; Lemaitre, J.-F.; Gueyffier, F.; Sanlaville, D.; Bardel, C.; Vieira, C.; Marais, G. A.; Plotton, I.
10.1101/2023.08.03.550779 — genomics — Posted on 2024-07-08
4009 A highly divergent mitochondrial genome in extant Cape buffalo from Addo Elephant National Park, South Africa
de Jager, D.; Moller, M.; Hoal, E. G.; van Helden, P.; Glanzmann, B.; Harper, C. K.; Bloomer, P.
10.1101/2023.01.14.524049 — genetics — Posted on 2024-07-08
4012 Hexokinase 2 expression in apical enterocytes correlates with inflammation severity in patients with inflammatory bowel disease
Weber-Stiehl, S.; Taubenheim, J.; Jaerke, L.; Roecken, C.; Schreiber, S.; Aden, K.; Kaleta, C.; Rosenstiel, P.; Sommer, F.
10.1101/2024.04.04.588060 — immunology — Posted on 2024-07-08
4013 Physical constraints on the positions and dimensions of the zebrafish swim bladder by surrounding bones
Satoh, K.; Maeno, A.; Adachi, U.; Ishizaka, M.; Yamada, K.; Koita, R.; Nakazawa, H.; Oikawa, S.; Fujii, R.; Furudate, H.; Kawamura, A.
10.1101/2024.07.04.602051 — developmental biology — Posted on 2024-07-08
4014 Tks5 interactome reveals ER-associated machinery translation in invadosomes.
NORMAND, L.; BONNARD, B.; Sala, M.; DI-TOMMASO, S.; DOURTHE, C.; RAYMOND, A.-A.; DUPUY, J.-W.; MERCIER, L.; GOETZ, J. G.; MOREAU, V.; HENRIET, E.; SALTEL, F.
10.1101/2024.07.02.601728 — cancer biology — Posted on 2024-07-08
4015 Transcriptomic Hallmarks of Mortality Reveal Universal and Specific Mechanisms of Aging, Chronic Disease, and Rejuvenation
Tyshkovskiy, A.; Kholdina, D.; Ying, K.; Davitadze, M.; Moliere, A.; Tongu, Y.; Kasahara, T.; Kats, L. M.; Vladimirova, A.; Moldakozhayev, A.; Liu, H.; Zhang, B.; Khasanova, U.; Moqri, M.; Van Raamsdonk, J. M.; Harrison, D. E.; Strong, R.; Abe, T.; Dmitriev, S. E.; Gladyshev, V. N.
10.1101/2024.07.04.601982 — systems biology — Posted on 2024-07-07
4016 Shikimate pathway-Dependent Catabolism:enabling near-to-maximum production yield of aromatics
Bruinsma, L.; Batianis, C.; Moreno Paz, S.; Kurnia, K.; Dirkmaat, J.; Muller, A.; Juncosa Nunez, J.; Weusthuis, R.; Martins dos Santos, V. A. P.
10.1101/2024.07.06.602327 — synthetic biology — Posted on 2024-07-07
4017 Multi-omic profiling of intraductal papillary neoplasms of the pancreas reveals distinct expression patterns and potential markers of progression
Wang, Y.; Lih, T.-S. M.; Lee, J. W.; Ohtsuka, T.; Hozaka, Y.; Mino-Kenudson, M.; Adsay, N. V.; Luchini, C.; Scarpa, A.; Maker, A. V.; Kim, G. E.; Paulino, J.; Chen, L.; Jiao, L.; Sun, Z.; Goodman, D.; Pfluger, M. J.; Roberts, N. J.; Matthaei, H.; Wood, L. D.; Furukawa, T.; Zhang, H.; Hruban, R. H.
10.1101/2024.07.07.602385 — cancer biology — Posted on 2024-07-07
4019 Hedgehog-Hippo pathway interactions promote T cell exclusion from the tumor microenvironment in basal cell carcinoma
Aberger, F.; Stockmaier, G.; Varkhande, S.; Krenn, P. W.; Dang, H.-h.; Sharma, A.; Elmer, D. P.; Steiner, M.; Zaborsky, N.; Neureiter, D.; Greil, R.; Horejs-Hoeck, J.; Fortelny, N.; Gratz, I. K.
10.1101/2024.07.07.602398 — cancer biology — Posted on 2024-07-07
4022 Breaking free from references: a consensus-based approach for community profiling with long amplicon nanopore data
Stock, W.; Rousseau, C.; Dierickx, G.; D'hondt, S.; Martinez, L. A.; Dittami, S. M.; van der Loos, L.; De Clerck, O.
10.1101/2024.07.04.602031 — bioinformatics — Posted on 2024-07-07
4025 Ultra-resolution Deconvolution of Spatial Transcriptomics Unveils Spatiotemporal Cellular Dynamics in Complex Microenvironments
Xu, Y.; Huang, Z.; Zhang, Y.; Wang, Z.; Guo, P.; Zhang, F.; Gong, W.; Liang, G.; Mei, B.; Dong, L.; Chang, R.; Gong, M.; Xia, Y.; Ni, H.; Yang, J.; Gao, Y.; Liu, Z.; Shen, L.; Li, J.; Xu, M. M.; Han, D.
10.1101/2024.07.05.602200 — bioinformatics — Posted on 2024-07-07
4028 'Target-and-release' nanoparticles for effective immunotherapy of metastatic ovarian cancer
Pires, I. S.; Covarrubias, G.; Gomerdinger, V. F.; Backlund, C. M.; Shanker, A.; Gordon, E.; Wu, S.; Pickering, A. J.; Melo, M. B.; Suh, H.; Irvine, D. J.; Hammond, P. T.
10.1101/2024.07.05.602135 — bioengineering — Posted on 2024-07-07
4029 In vivo CRISPR base editing for treatment of Huntington's disease
Shirguppe, S.; Gapinske, M.; Swami, D.; Gosstola, N.; Acharya, P.; Miskalis, A.; Joulani, D.; Szkwarek, M. G.; Bhattacharjee, A.; Elias, G.; Stilger, M.; Winter, J.; Woods, W. S.; Anand, D.; Lim, C. K. W.; Gaj, T.; Perez-Pinera, P.
10.1101/2024.07.05.602282 — bioengineering — Posted on 2024-07-07
4030 Quantification and site-specific analysis of co-occupied N- and O-glycopeptides
Chongsaritsinsuk, J.; Rangel-Angarita, V.; Mahoney, K. E.; Lucas, T. M.; Enny, O. M.; Katemauswa, M.; Malaker, S. A.
10.1101/2024.07.06.602348 — biochemistry — Posted on 2024-07-07
4031 Discovery and mechanism of K63-linkage-directed deubiquitinase activity in USP53
Wendrich, K.; Gallant, K.; Recknagel, S.; Petroulia, S.; Führer, S.; Bezstarosti, K.; O'Dea, R.; Demmers, J.; Gersch, M.
10.1101/2024.07.07.602376 — biochemistry — Posted on 2024-07-07
4032 Hierarchical structural organization in bioinspired peptide coacervate microdroplets
Lim, J.; Gudlur, S.; Buchanan, C.; Perrin, Q.; Boyd, H.; Moulin, M.; Iwase, H.; Porcar, L.; Cardenas, M.; Miserez, A.; Pervushin, K.
10.1101/2024.07.06.602323 — biochemistry — Posted on 2024-07-07
4035 Insights into non-crossover recombination from long-read sperm sequencing
Schweiger, R.; Lee, S.; Zhou, C.; Yang, T.-P.; Smith, K.; Li, S.; Sanghvi, R.; Neville, M.; Mitchell, E.; Nessa, A.; Wadge, S.; Small, K. S.; Campbell, P. J.; Sudmant, P. H.; Rahbari, R.; Durbin, R.
10.1101/2024.07.05.602249 — genetics — Posted on 2024-07-07
4036 Frequent transitions in self-assembly across the evolution of a central metabolic enzyme
Sendker, F. L.; Schlotthauer, T.; Mais, C.-N.; Lo, Y. K.; Girbig, M.; Bohn, S.; Heimerl, T.; Schindler, D.; Weinstein, A.; Metzger, B. P.; Thornton, J. W.; Pillai, A.; Bange, G.; Schuller, J.; Hochberg, G.
10.1101/2024.07.05.602260 — evolutionary biology — Posted on 2024-07-07
4037 Plastid translocon recycling in dinoflagellates demonstrates the portability of complex plastids between hosts
Lewis, W. H.; Paris, G.; Beedessee, G.; Koreny, L.; Flores, V.; Dendooven, T.; Gallet, B.; Yee, D. P.; Lam, S.; Decelle, J.; Luisi, B.; Waller, R. F.
10.1101/2024.07.06.602338 — evolutionary biology — Posted on 2024-07-07
4038 A probabilistic view of forbidden links: their prevalence and their consequences for the robustness of mutualistic networks
Duchenne, F.; Barreto, E.; Guevara, E. A.; Beck, H.; Bello, C.; Bobato, R.; Bolla, D.; Brenes, E.; Büttner, N.; Caron, A. P.; Elizondo, N.; Restrepo-Gonzalez, A.; Castro, J. A.; Kaehler, M.; Machado-de-Souza, T.; Machnicki-Reis, M.; Marcayata-Fajardo, A. S.; de Menezes, C. G.; Nieto, A.; de Oliveira, R.; de Oliveira, R. A. C.; Richter, F.; Rojas, B. G.; Romanowski, L. L.; de Souza, W. L.; Veluza, D. S.; Weinstein, B.; Wüest, R.; Zanata, T. B.; Zuniga, K.; Maglianesi, M. A.; Santander, T.; Varassin, I. G.; Graham, C. H.
10.1101/2024.07.04.602032 — ecology — Posted on 2024-07-07
4039 A conserved RNA switch for acetylcholine receptor clustering at neuromuscular junctions in chordates
Hossain, M. F.; Popsuj, S.; Vitrinel, B.; Kaplan, N. A.; Stolfi, A.; Christiaen, L.; Ruggiu, M.
10.1101/2024.07.05.602308 — developmental biology — Posted on 2024-07-07
4040 Spatial organization of PI3K-PI(3,4,5)P3-AKT signaling by focal adhesions
Wang, J.; An, Z.; Wu, Z.; Zhou, W.; Sun, P.; Wu, P.; Xue, R.; Dang, S.; Bai, X.; Wang, W.; Chen, R.; Du, Y.; Huang, P.; Lam, S. M.; Ai, Y.; Liu, S.; Shui, G.; Zhang, Z.; Liu, Z.; Huang, J.; Fang, X.; He, K.
10.1101/2024.07.05.602013 — cell biology — Posted on 2024-07-07
4041 INF2-mediated actin polymerization at ER-organelle contacts regulates organelle size and movement
Schiavon, C. R.; Wang, Y.; Feng, J. W.; Garrett, S.; Dayn, Y.; Sung, T.-C.; Wang, C.; Youle, R. J.; Quintero-Carmona, O. A.; Shadel, G. S.; Manor, U.
10.1101/2024.07.06.602365 — cell biology — Posted on 2024-07-07
4044 Treatment with 2-phospho-L-ascorbic acid mitigates biochemical phenotypes of heme oxygenase 1 deficiency
Berendes, L.-S.; Schulze Westhoff, P.; Tobinski, A.-M.; Wingert, V.; Biskup, S.; Seelhoefer, A.; Van Marck, V.; Heitplatz, B.; Wittkowski, H.; Das, A. M.; Hannibal, L.; Nowak, W. N.; Jozkowicz, A.; Klotz, L.; Varga, G.; Marquardt, T.; Park, J. H.
10.1101/2024.07.05.602073 — molecular biology — Posted on 2024-07-07
4046 RNA genome expansion up to 64 kb in nidoviruses is host constrained and associated with new modes of replicase expression
Neuman, B. W.; Smart, A.; Vaas, J.; Bartenschlager, R.; Seitz, S.; Gorbalenya, A. E.; Caliskan, N. E.; Lauber, C.
10.1101/2024.07.07.602380 — microbiology — Posted on 2024-07-07
4048 Co-option of mitochondrial nucleic acid sensing pathways by HSV-1 UL12.5 for reactivation from latent Infection
Cuddy, S.; Krakowiak, P. A.; Flores, M. E.; Whitford, A. L.; Dochnal, S. A.; Babnis, A.; Miyake, T.; Tigano, M.; Engel, D. A.; Cliffe, A. R.
10.1101/2024.07.06.601241 — microbiology — Posted on 2024-07-07
4049 Single-cell omics for complex microbial communities
Lan, X.; Liang, Q.; Wu, J.; He, J.; Zhang, X.; Li, F.; Zhao, G.-P.; Guo, R.; Jia, H.
10.1101/2024.07.07.602369 — microbiology — Posted on 2024-07-07
4050 Integrative genomic reconstruction of carbohydrate utilization networks in bifidobacteria: global trends, local variability, and dietary adaptation
Arzamasov, A. A.; Rodionov, D. A.; Hibberd, M. C.; Guruge, J. L.; Kazanov, M. D.; Leyn, S. A.; Kent, J. E. D.; Sejane, K.; Bode, L.; Barratt, M. J.; Gordon, J.; Osterman, A.
10.1101/2024.07.06.602360 — microbiology — Posted on 2024-07-07
4052 Identification of P-type ATPase as a bacterial transporter for host-derived small RNA
Dong, P.-T.; Yang, M.; Cen, L.; Zhou, P.; Xu, D.; Xiong, P.; Wu, C.; Li, J.; He, X.
10.1101/2024.07.05.602285 — microbiology — Posted on 2024-07-07
4054 Interspecies interaction reshapes the fitness landscape of evolved genotypes
Sun, X.; Xu, Z.; Hu, G.; Xie, J.; Li, Y.; Tao, L.; Zhang, N.; Xun, W.; Miao, Y.; Zhang, R.; Shen, Q.; Kovacs, A. T.
10.1101/2024.07.06.602328 — microbiology — Posted on 2024-07-07
4055 Comparing Raman and NanoSIMS for heavy water labeling of single cells
Schaible, G.; Cliff, J.; Crandall, J.; Bougoure, J.; Atwood, J.; Hatzenpichler, R.
10.1101/2024.07.05.602271 — microbiology — Posted on 2024-07-07
4056 Multiple stressor effects on organic carbon degradation and microbial community composition in urban river sediments in a mesocosm experiment
Baikova, D.; Hadziomerovic, U.; Madge Pimentel, I.; Buchner, D.; Vermiert, A.-M.; Rehsen, P. M.; Brauer, V.; Meckenstock, R. U.
10.1101/2024.07.05.602289 — microbiology — Posted on 2024-07-07
4057 Acidotolerant soil nitrite oxidiser 'Candidatus Nitrobacter laanbroekii' NHB1 alleviates constraints on growth of acidophilic soil ammonia oxidisers
Hink, L.; Bachtsevani, E.; Meng, Y.; Sedlacek, C. J.; Lee, S.; Daims, H.; Wagner, M.; Gubry-Rangin, C.; de Boer, W.; Hazard, C.; Prosser, J. I.; Nicol, G. W.
10.1101/2024.07.06.601931 — microbiology — Posted on 2024-07-07
4058 Diel changes in the expression of a marker gene and candidate genes for intracellular amorphous CaCO3 biomineralization in Microcystis
Bruley, A.; Gaëtan, J.; Gugger, M.; Pancrace, C.; Millet, M.; Gaschignard, G.; Dezi, M.; Humbert, J.-F.; Leloup, J.; Skouri-Panet, F.; Callebaut, I.; Benzerara, K.; Duprat, E.
10.1101/2024.07.07.602159 — microbiology — Posted on 2024-07-07
4060 Synergically enhanced anti-tumor immunity of in vivo CAR by circRNA vaccine boosting
Wang, Y.; Lin, L.; Wang, X.; Li, J.; Yin, J.; Gao, F.; Liao, X.; Zhang, C.; Yin, Q.; Zhao, C.; Lin, J.; Xu, Y.; Qiu, M.; Luo, D.; Qu, L.
10.1101/2024.07.05.600312 — immunology — Posted on 2024-07-07
4061 Rebalancing Viral and Immune Damage versus Tissue Repair Prevents Death from Lethal Influenza Infection
Ichise, H.; Speranza, E.; La Russa, F.; Veres, T. Z.; Chu, C. J.; Gola, A.; Germain, R. N.
10.1101/2024.07.04.601620 — immunology — Posted on 2024-07-07
4063 Inhibitory neurons defined by a synaptogenic molecule impair memory discrimination
Tunon-Ortiz, A. B. N.; Trankner, D.; Raines, O. K.; Mahnke, A.; Brockway, S.; Grega, M.; Zelikowsky, M.; Williams, M. E.
10.1101/2024.07.05.602304 — neuroscience — Posted on 2024-07-07
4067 Membrane permeability selection drove the stereochemistry of life
Goode, O.; Lapinska, U.; Glover, G.; Milner, D. S.; Santoro, A. E.; Pagliara, S.; Richards, T.
10.1101/2024.04.23.590732 — evolutionary biology — Posted on 2024-07-08
4068 Ilamycin E and ilamycin F are dual inhibitors of ClpX and ClpC1 in mycobacteria
Gao, Y.; Fang, C.; Zhou, B.; Hameed, H. M. A.; Sun, C.; Tian, X.; He, J.; Han, X.; Zhang, H.; Ju, J.; Chen, X.; Zhong, N.; Ma, J.; Xiong, X.; Zhang, T.
10.1101/2024.02.24.581832 — microbiology — Posted on 2024-07-08
4069 E. coli division machinery drives cocci development inside host cells
Pokhrel, A.; Costas, A.; Pittorino, M.; Duggin, I. G.; Söderström, B.
10.1101/2024.04.08.588611 — microbiology — Posted on 2024-07-08
4070 Synthesis and Biological Assessment of Chalcone and Pyrazoline Derivatives as novel inhibitor for ELF3-MED23 Interaction
Hwang, S.-Y.; Jeon, K.-H.; Lee, H.-J.; Moon, I.; Jung, S.; Kim, S.-A.; Jo, H.; Park, S.; Ahn, M.; Kwak, S.-Y.; Na, Y.; Kwon, Y.
10.1101/2024.03.01.583029 — pharmacology and toxicology — Posted on 2024-07-08
4071 Determination of the absolute concentration of Rayleigh particles via scattering microscopy
Lee, I.-B.; Moon, H.-M.; Park, J.-S.; Lee, S.-H.; Lee, J.; Park, S. H.; Lee, S.; Hong, S.-C.; Cho, M.
10.1101/2024.06.08.598040 — biophysics — Posted on 2024-07-08
4072 AutoPeptideML: A study on how to build more trustworthy peptide bioactivity predictors
Fernandez-Diaz, R.; Cossio-Perez, R.; Agoni, C.; Hoang, L. T.; Lopez, V.; Shields, D. C.
10.1101/2023.11.13.566825 — bioinformatics — Posted on 2024-07-08
4075 N-acetyl-transferases required for iron uptake and aminoglycoside resistance promote virulence lipid production in M. marinum
Jones, B. S.; Pareek, V.; Hu, D. D.; Weaver, S. D.; Syska, C.; Galfano, G.; Champion, M.; Champion, P. A.
10.1101/2024.07.05.602253 — microbiology — Posted on 2024-07-07
4076 Multiple independent acquisitions of ACE2 usage in MERS-related coronaviruses
Ma, C.-B.; Liu, C.; Park, Y.-J.; Tang, J.; Chen, J.; Xiong, Q.; Lee, J.; Stewart, C.; Asarnow, D.; Brown, J.; Tortorici, M. A.; Yang, X.; Sun, Y.-H.; Chen, Y.-M.; Yu, X.; Si, J.-Y.; Liu, P.; Tong, F.; Huang, M.-L.; Li, J.; Shi, Z.-L.; Deng, Z.; Veesler, D.; Yan, H.
10.1101/2023.10.02.560486 — microbiology — Posted on 2024-07-08
4080 Shikimate pathway-Dependent Catabolism:enabling near-to-maximum production yield of aromatics
Bruinsma, L.; Batianis, C.; Moreno Paz, S.; Kurnia, K.; Dirkmaat, J.; Muller, A.; Juncosa Nunez, J.; Weusthuis, R.; Martins dos Santos, V. A. P.
10.1101/2024.07.06.602327 — synthetic biology — Posted on 2024-07-07
4082 Multiple stressor effects on organic carbon degradation and microbial community composition in urban river sediments in a mesocosm experiment
Baikova, D.; Hadziomerovic, U.; Madge Pimentel, I.; Buchner, D.; Vermiert, A.-M.; Rehsen, P. M.; Brauer, V.; Meckenstock, R. U.
10.1101/2024.07.05.602289 — microbiology — Posted on 2024-07-07
4083 Interspecies interaction reshapes the fitness landscape of evolved genotypes
Sun, X.; Xu, Z.; Hu, G.; Xie, J.; Li, Y.; Tao, L.; Zhang, N.; Xun, W.; Miao, Y.; Zhang, R.; Shen, Q.; Kovacs, A. T.
10.1101/2024.07.06.602328 — microbiology — Posted on 2024-07-07
4084 Identification of P-type ATPase as a bacterial transporter for host-derived small RNA
Dong, P.-T.; Yang, M.; Cen, L.; Zhou, P.; Xu, D.; Xiong, P.; Wu, C.; Li, J.; He, X.
10.1101/2024.07.05.602285 — microbiology — Posted on 2024-07-07
4086 Targeting mitochondrial metabolism with CPI-613 in chemoresistant ovarian tumors
Udumula, M. P.; Rashid, F.; Singh, H.; Pardee, T.; Luther, S.; Bhardwaj, T.; Anjaly, K.; Piloni, S.; Hijaz, M.; Gogoi, R.; Philip, P. A.; Munkarah, A.; Giri, s.; Rattan, R.
10.1101/2024.05.16.594585 — cancer biology — Posted on 2024-07-07
4089 CRF release from a unique subpopulation of accumbal neurons constrains action-outcome acquisition in reward learning
Eckenwiler, E. A.; Ingebretson, A. E.; Stolley, J. J.; Fusaro, M. A.; Romportl, A. M.; Ross, J. M.; Petersen, C. L.; Kale, E. M.; Clark, M. S.; Schattauer, S. S.; Zweifel, L. S.; Lemos, J. C.
10.1101/2023.11.16.567495 — neuroscience — Posted on 2024-07-07
4090 Zero-shot animal behavior classification with vision-language foundation models
Dussert, G.; Miele, V.; Van Reeth, C.; Delestrade, A.; Dray, S.; Chamaille-Jammes, S.
10.1101/2024.04.05.588078 — ecology — Posted on 2024-07-07
4091 Discovery of a novel albendazole-ivermectin refractory Trichuris species, T. hominis, in Cote d'Ivoire patients through fecal DNA metabarcoding
Venkatesan, A.; Chen, R.; Bär, M. A.; Schneeberger, P.; Reimer, B.; Hürlimann, E.; Coulibaly, J. T.; Ali, S. M.; Sayasone, S.; Soghigian, J.; Keiser, J.; Gilleard, J. S.
10.1101/2024.07.04.602123 — genomics — Posted on 2024-07-07
4093 Heightened lateral habenula activity during stress produces brainwide and behavioral substrates of susceptibility
Zhukovskaya, A.; Christopher, Z.; Willmore, L.; Pan Vazquez, A.; Janarthanan, S.; Falkner, A.; Witten, I.
10.1101/2023.11.06.565681 — neuroscience — Posted on 2024-07-07
4096 Altered cortico-cerebellar connectivity in cerebellar degeneration patients improves with motor training
Nettekoven, C.; Draganova, R.; Steiner, K. M.; Goericke, S. L.; Deistung, A.; Konczak, J.; Timmann, D.
10.1101/2024.07.05.602300 — neuroscience — Posted on 2024-07-06
4098 Dual-mode action of scalable, high-quality engineered stem cell-derived SIRPα-extracellular vesicles for treating acute liver failure
Kim, S.; Kim, Y. K.; Kim, S.; Choi, Y.-S.; Lee, I.; Joo, H.; Kim, J.; Kwon, M.; Park, S.; Jo, M. K.; Choi, Y.; D'Souza, T.; Jung, J. W.; Zakhem, E.; Lenzini, S.; Woo, J.; Choi, H.; Park, J.; Park, S.-Y.; Kim, G. B.; Nam, G.-H.; Kim, I.-S.
10.1101/2024.05.24.592430 — bioengineering — Posted on 2024-07-07
4099 A metabolic modeling-based framework for predicting trophic dependencies in native rhizobiomes of crop plants
Ginatt, A. A.; Berihu, M.; Castel, E.; Medina, S.; Carmi, G.; Doron-Faigenboim, A.; Sharon, I.; Tal, O.; Droby, S.; Somera, T.; Mazzola, M.; Eizenberg, H.; Freilich, S.
10.1101/2023.12.11.571117 — microbiology — Posted on 2024-07-07
4100 Prdm1 Positively Regulates Liver Group 1 ILCs Cancer Immune Surveillance and Preserves Functional Heterogeneity
He, J.; Gao, L.; Wang, P.; Chan, W. K.; Zheng, Y.; Zhang, Y.; Sun, J.; Li, X.; Wang, J.; Li, X.; Chen, H.; Yang, Z.; Wang, Y.
10.1101/2023.10.20.563222 — immunology — Posted on 2024-07-07
4101 Comparing arm to whole-body motor control disambiguates age-related deterioration from compensation
Mathieu, R.; Chambellant, F.; Thomas, E.; Papaxanthis, C.; Hilt, P.; Manckoundia, P.; Mourey, F.; Gaveau, J.
10.1101/2024.02.16.576683 — neuroscience — Posted on 2024-07-07
4103 Cortical circuits for cross-modal generalization
Guyoton, M.; Matteucci, G.; Foucher, C. G.; Getz, M. P.; Gjorgjieva, J.; El-Boustani, S.
10.1101/2023.10.13.562215 — neuroscience — Posted on 2024-07-06
4104 HyperPRI: A Dataset of Hyperspectral Images for Underground Plant Root Study
Chang, S. J.; Chowdhry, R.; Song, Y.; Mejia, T.; Hampton, A.; Kucharski, S.; Sazzad, T.; Zhang, Y.; Koppal, S. J.; Wilson, C. H.; Gerber, S.; Tillman, B.; Resende, M. F.; Hammond, W. M.; Zare, A.
10.1101/2023.09.29.559614 — plant biology — Posted on 2024-07-06
4105 Transposable element expression with variation in sex chromosome number: insights into a toxic Y effect on human longevity
Teoli, J.; Merenciano, M.; Fablet, M.; Necsulea, A.; Siqueira-de-Oliveira, D.; Brandulas-Cammarata, A.; Labalme, A.; Lejeune, H.; Lemaitre, J.-F.; Gueyffier, F.; Sanlaville, D.; Bardel, C.; Vieira, C.; Marais, G. A.; Plotton, I.
10.1101/2023.08.03.550779 — genomics — Posted on 2024-07-06
4106 Draft genomes of a male and female Australian jacky dragon (Amphibolurus muricatus)
Tian, R.; Dong, H.; Zhang, F.; Yu, H.; Pei, E.; Shi, C.; Fan, G.; Whiteley, S. L.; Holleley, C. E.; Seim, I.; Georges, A.
10.1101/2021.10.11.463868 — genomics — Posted on 2024-07-06
4107 Mitochondria-derived Vesicles mediate Mito-nuclear Trafficking of Cargo
Rajeev, T.; Shil, D.; Bhattacharjee, S.; Ramesh, L.; Samuel, V.; Nair, N. Y.; Marib, A.; Jayakumar, M.; Gayathri, S.; Surendran, A.; Johnson, J. B.; Sundararaman, A.
10.1101/2024.05.04.592299 — cell biology — Posted on 2024-07-06
4109 Cellular and molecular events organizing the assembly of tertiary lymphoid structures in glioblastoma
Vaccaro, A.; Yang, F.; van de Walle, T.; Franke, S.; Lugano, R.; Denes, A.; Magoulopoulou, A.; Cid-Farina, I.; Smits, A.; Uhrbom, L.; Libard, S.; Latini, F.; Essand, M.; Nilsson, M.; He, L.; Olsson Bontell, T.; Jakola, A. S.; Ramachandran, M.; Dimberg, A.
10.1101/2024.07.04.601824 — cancer biology — Posted on 2024-07-06
4110 Worldwide Soundscapes: a synthesis of passive acoustic monitoring across realms
Darras, K. F.; Rountree, R.; Van Wilgenburg, S.; Cord, A. F.; Pitz, F.; Chen, Y.; Dong, L.; Gasc, A.; Lin, T.-H.; Diaz, P. M.; Wu, S.-H.; Salton, M.; Marley, S.; Schille, L.; Wensveen, P. J.; Desjonqueres, C.; Acevedo-Charry, O.; Adam, M.; Aguzzi, J.; Andre, M.; Antonelli, A.; Aparecido Do Nascimento, L.; Appel, G.; Astaras, C.; Atemasov, A.; Barbaro, L.; Basan, F.; Batist, C.; Baucells, A. L.; Baumgarten, J. E.; Bayle Sempere, J. T.; Bellisario, K.; Ben David, A.; Berger-Tal, O.; Betts, M. G.; Bhalla, I.; Bicudo, T.; Bolgan, M.; Bombaci, S.; Boullhesen, M.; Bradfer-Lawrence, T.; Briers, R. A.
10.1101/2024.04.10.588860 — ecology — Posted on 2024-07-06
4111 Seq2scFv: a toolkit for the comprehensive analysis of display libraries from long-read sequencing platforms
Bachmann Salvy, M.; Santuari, L.; Schmid-Siegert, E.; Lykoskoufis, N. M. R.; Xenarios, I.; Arpat, B.
10.1101/2024.07.04.602016 — immunology — Posted on 2024-07-06
4113 PVN-mPFC OT projections modulates pup-directed pup care or attacking in virgin mandarin voles
Li, L.; Li, Y.; Huang, C.; Hou, W.; Lv, Z.; Zhang, L.; Qu, Y.; Sun, Y.; Huang, K.; Han, X.; He, Z.; Tai, F.-D.
10.1101/2024.03.06.583718 — neuroscience — Posted on 2024-07-06
4114 Enhanced purinergic signaling in the paraventricular hypothalamus induces hyperphagic obesity and insulin resistance
Liu, Y.; Zhang, H.; Zhang, Q.; Najam, S. S.; Liang, X.; Sirakawin, C.; Lin, D.; Huang, S.; Bondarenko, A.; Konopka, W.; Zhang, Y.; Zhang, Z.; Wu, S.; Jing, M.; Vinnikov, I. A.
10.1101/2024.07.02.601503 — neuroscience — Posted on 2024-07-06
4119 Co-Transplantation-Based Human-Mouse Chimeric Brain Models to Study Human Glial-Glial and Glial-Neuronal Interactions
Jin, M.; Ma, Z.; Zhang, H.; Papetti, A. V.; Dang, R.; Stillitano, A. C.; Goldman, S. A.; Jiang, P.
10.1101/2024.07.03.601990 — neuroscience — Posted on 2024-07-06
4120 Atypical chemokine receptor 3 regulates synaptic removal in disease astrocytes
Giusti, V.; Park, J.; Giusto, E.; Masatti, L.; Ramos-Gonzales, P.; Iovino, L.; Sandre, M.; Emmi, A.; Kaur, G.; Coletto, E.; Calura, E.; Petrelli, F.; Porzionato, A.; De Caro, R.; Cavaliere, F.; Chung, W.-S.; Civiero, L.
10.1101/2024.07.03.601867 — neuroscience — Posted on 2024-07-06
4123 Comparing arm to whole-body motor control disambiguates age-related deterioration from compensation
Mathieu, R.; Chambellant, F.; Thomas, E.; Papaxanthis, C.; Hilt, P.; Manckoundia, P.; Mourey, F.; Gaveau, J.
10.1101/2024.02.16.576683 — neuroscience — Posted on 2024-07-06
4124 Bait, not reward: CO2-enriched Nepenthes pitchers secrete toxic nectar
Lathika, C. C.; Sujatha, G. B.; Thomas, G.; Johnson, A. J.; Viswanathan, G.; Varghese, T. S.; Mohamed, S.; Shereefa, L. A.; Baby, S.
10.1101/2023.11.25.568661 — plant biology — Posted on 2024-07-06
4125 R2Dtool: Integration and visualization of isoform-resolved RNA features
Sethi, A. J.; Acera Mateos, P.; Hayashi, R.; Shirokikh, N. E.; Eyras, E.
10.1101/2022.09.23.509222 — bioinformatics — Posted on 2024-07-06
4128 An emerging PB2-627 polymorphism increases the pandemic potential of avian influenza virus by breaking through ANP32 host restriction in mammalian and avian hosts
Guo, Y.; Shu, S.; Zhou, Y.; Peng, W.; Jiang, Z.; Li, Y.; Li, T.; Du, F.; Wang, L.; Chen, X.; Dong, J.; Zhao, C.; Wang, M. H.; Sun, Y.; Sun, H.; Lu, L.; Digard, P.; Chang, K.-c.; Yen, H.-L.; Liu, J.; Pu, J.
10.1101/2024.07.03.601996 — microbiology — Posted on 2024-07-06
4130 qMAP Enabled Microanatomical Mapping of Human Skin Aging
Han, K. S.; Sander, I. B.; Kumer, J.; Resnick, E. P.; Booth, C.; Im, Y.; Cheng, G.; Starich, B.; Kiemen, A. L.; Phillip, J. M.; Reddy, S.; Joshu, C.; Sunshine, J.; Walston, J.; Wirtz, D.; Wu, P.-H.
10.1101/2024.04.03.588011 — pathology — Posted on 2024-07-06
4132 Estimating gene conversion tract length and rate from PacBio HiFi data
Charmouh, A. P.; Porsborg, P. S.; Bataillon, T.; Hobolth, A.; Hansen, L. T.; Besenbacher, S.; Winge, S. B.; Almstrup, K.; Schierup, M. H.
10.1101/2024.07.05.601865 — genomics — Posted on 2024-07-06
4133 Comprehensive Molecular Epidemiology of Influenza Viruses in Brazil: Insights from a Nationwide Analysis
Brcko, I. C.; de Souza, V. C.; Ribeiro, G.; Lima, A. R. J.; Martins, A. J.; Barros, C. R. d. S.; Carvalho, E.; Pereira, J. S.; de Lima, L. P. O.; Viala, V. L.; Kashima, S.; de La-Roque, D. G. L.; Santos, E. V.; Rodrigues, E. S.; Nunes, J. A.; Torres, L. S.; Caldeira, L. A. V.; Palmieri, M.; Medina, C. G.; Augusto de Arruda, R.; Lopes, R. B.; Reple Sobrinho, G.; Jorge, D. M. d. M.; Arruda, E.; Mendes, E. C. B. d. S.; Santos, H. d. O.; de Mello, A. L. e. S.; Pereira, F. M.; Gomez, M. K. A.; Nardy, V. B.; Henrique, B. V. M.; Vieira, L. L.; Roll, M. M.; de Oliveira, E. C.; Almeida, J. D. P. C.; da
10.1101/2024.07.04.602044 — evolutionary biology — Posted on 2024-07-06
4134 PD-1 blockade enhances HIV-1 vaccine-induced CD8+ T-cell responses in PWH early ART-treated
Marin, M.; Ruiz, A.; Jimenez-Moyano, E.; Ouchi, D.; Blanch-Lombarte, O.; Penya, R.; Gorman, D.; Barnard, R.; Hanke, T.; Clotet, B.; Howell, B. J.; Brander, C.; Mothe, B.; G Prado, J.
10.1101/2024.07.05.601669 — immunology — Posted on 2024-07-06
4136 SPArrOW: a flexible, interactive and scalable pipeline for spatial transcriptomics analysis
Pollaris, L.; Vanneste, B.; Rombaut, B.; Defauw, A.; Vernaillen, F.; Mortier, J.; Vanhenden, W.; Thone, T.; Martens, L.; Hastir, J.-F.; Bujko, A.; Saelens, W.; Marine, J.-C.; Nelissen, H.; Van Hamme, E.; Seurinck, R.; Scott, C. L.; Guilliams, M.; Saeys, Y.
10.1101/2024.07.04.601829 — bioinformatics — Posted on 2024-07-06
4138 Dokdo sea lion Zalophus japonicus genome reveals its evolutionary trajectory before extinction
Kim, J.; Blazyte, A.; Choi, J.-P.; Kim, C.; Sharko, F.; Jeon, S.; Kim, E.-M.; Sohn, H.; Lee, J. H.; Kim, H. W.; Yoo, M. H.; Lee, K.; Nedoluzhko, A.; Bhak, J.
10.1101/2024.07.04.602024 — genomics — Posted on 2024-07-06
4140 Evolutionary new centromeres in the snowy owl genome putatively seeded from a transposable element
Baalsrud, H. T.; Garmann-Aarhus, B.; Enevoldsen, E. L. G.; Krabberod, A. K.; Fischer, D.; Tooming-Klunderud, A.; Skage, M.; Arnyasi, M.; Sandve, S. R.; Jakobsen, K. S.; Nielsen, R.; Boessenkool, S.; Torresen, O. K.
10.1101/2024.07.05.602039 — genomics — Posted on 2024-07-06
4141 Repeat-rich regions cause false positive detection of NUMTs - a case study in amphibians using an improved cane toad reference genome
Cheung, K.; Rollins, L. A.; Hammond, J. M.; Barton, K.; Ferguson, J. M.; Eyck, H. J. F.; Shine, R.; Edwards, R. J.
10.1101/2024.07.04.601973 — genomics — Posted on 2024-07-06
4142 Deciphering the variation in cuticular hydrocarbon profiles of five European honey bee subspecies
Rodriguez-Leon, D. S.; Uzunov, A.; Costa, C.; Dylan, E. S.; Charistos, L.; Galea, T.; Gabel, M.; Scheiner, R.; Pinto, M. A.; Schmitt, T.
10.1101/2024.07.05.601031 — evolutionary biology — Posted on 2024-07-06
4143 Insights into gene conversion and crossing-over processes from long-read sequencing of human, chimpanzee and gorilla testes and sperm
Porsborg, P. S.; Charmouh, A. P.; Singh, V.; Winge, S. B.; Hvilsom, C.; Pelizzola, M.; Laurentino, S.; Neuhaus, N.; Hobolth, A.; Bataillon, T.; Almstrup, K.; Besenbacher, S.; Schierup, M. H.
10.1101/2024.07.05.601967 — evolutionary biology — Posted on 2024-07-06
4144 Distinct modes of holobiont specialization among cryptic coral lineages
Grupstra, C. G. B.; Meyer-Kaiser, K. S.; Bennett, M.-J.; Andres, M. O.; Juszkiewicz, D. J.; Fifer, J. E.; Da-Anoy, J. P.; Gomez-Campo, K.; Martinez-Rugerio, I.; Aichelman, H. E.; Huzar, A. K.; Hughes, A. M.; Rivera, H. E.; Davies, S. W.
10.1101/2024.07.05.598868 — ecology — Posted on 2024-07-06
4145 Food texture preference reveals multisensory contributions of gustatory organs in behaviour and physiology
Komarov, N.; Fritsch, C.; Maier, G. L.; Bues, J.; Biocanin, M.; Avalos, C. B.; Dodero, A.; Kwon, J. Y.; Deplancke, B.; Sprecher, S. G.
10.1101/2024.07.04.602043 — neuroscience — Posted on 2024-07-06
4146 Pan-cortical cellular imaging in freely behaving mice using a miniaturized micro-camera array microscope (mini-MCAM)
Hu, J.; Cherkkil, A.; Surinach, D. A.; Oladepo, I.; Hossain, R. F.; Fausner, S.; Saxena, K.; Ko, E.; Peters, R.; Feldkamp, M.; Konda, P. C.; Pathak, V.; Horstmeyer, R.; Kodandaramaiah, S. B.
10.1101/2024.07.04.601964 — neuroscience — Posted on 2024-07-06
4147 Generative deep learning models for cognitive performance trajectories in real-world scenarios
Exposito Navarro, D.; Maltseva, E.; Sastre-Barrios, C.; Fernandez de Pierola, I.; Cortes, J.
10.1101/2024.07.05.600608 — neuroscience — Posted on 2024-07-06
4151 SOX21 suppresses GBM growth by repressing AP-1 regulated target genes
Muhr, J.; Rrapaj, E.; Yuan, J.; Kurtsdotter, I.; Misyurin, V.; Baselli, G.; Persson, O.; Bergsland, M.
10.1101/2024.07.05.601643 — cancer biology — Posted on 2024-07-06
4153 N-acetyl-transferases required for iron uptake and aminoglycoside resistance promote virulence lipid production in M. marinum
Jones, B. S.; Pareek, V.; Hu, D. D.; Weaver, S. D.; Syska, C.; Galfano, G.; Champion, M.; Champion, P. A.
10.1101/2024.07.05.602253 — microbiology — Posted on 2024-07-06
4155 "Magnetic Sand" : Illusions of Interactivity
Shimojo, S.; Shimojo, K.; Shimojo, E.; Zheng, S.; Wu, D.-A.
10.1101/2024.07.03.598775 — neuroscience — Posted on 2024-07-06
4162 Structural Characterization of DNA Binding Domain of Essential Mammalian Protein TTF 1
Singh, G.; Bhopale, A. J.; Khatri, S.; Prakash, P.; Kumar, R.; Singh, S. M.; Singh, S. K.
10.1101/2024.07.05.602234 — biochemistry — Posted on 2024-07-06
4163 SYSTEMIC FRATAXIN DEFICIENCY CAUSES TISSUE-DEPENDENT IRON HOMEOSTASIS ALTERATIONS: IMPLICATIONS FOR FRIEDREICH ATAXIA
Pazos-Gil, M.; Medina-Carbonero, M.; Sanz-Alcazar, A.; Portillo-Carrasquer, M.; Oliveira, L.; Hernandez, G.; Sanchez, M.; Delaspre, F.; Cabiscol, E.; Ros, J.; Tamarit, J.
10.1101/2024.07.05.602088 — biochemistry — Posted on 2024-07-06
4164 Nanotiming: telomere-to-telomere DNA replication timing profiling by nanopore sequencing
Theulot, B.; Tourancheau, A.; Simonin Chavignier, E.; Jean, E.; Arbona, J.-M.; Audit, B.; Hyrien, O.; Lacroix, L.; Le Tallec, B.
10.1101/2024.07.05.602252 — genomics — Posted on 2024-07-06
4167 The complete mitogenome of an unidentified Oikopleura species
Wibisana, J. N.; Plessy, C.; Dierckxsens, N.; Masunaga, A.; Luscombe, N.
10.1101/2024.07.04.602139 — genomics — Posted on 2024-07-06
4168 No phenotypic consequences of archaic hominin alleles in present-day humans
Molz, B.; Lana Alberro, M.; Eising, E.; Schijven, D.; Alagöz, G.; Francks, C.; Fisher, S. E.
10.1101/2024.07.05.602242 — genetics — Posted on 2024-07-06
4170 Quantifying Forest Biomass and Genetic Contribution using Light Detection and Ranging
Sano, H.; Miura, N.; Inamori, M.; Unno, Y.; Guo, W.; Isobe, S.; Kusunoki, K.; Iwata, H.
10.1101/2024.07.03.601985 — genetics — Posted on 2024-07-06
4172 Recommendations for Population and Individual Diagnostic SNP Selection in Non-Model Species
Armstrong, E. E.; Li, C.; Campana, M. A.; Ferrari, T.; Kelley, J. L.; Petrov, D.; Solari, K. A.; Mooney, J. A.
10.1101/2024.07.03.601943 — evolutionary biology — Posted on 2024-07-06
4175 The first report on the effect of white and black truffle extracts on human semen parameters in vitro
Shelkovnikova, V.; Dmitrieva, M.; Malygina, E.; Imidoeva, N.; Belyshenko, A.; Morgunova, M.; Vlasova, A.; Telnova, T.; Batalova, A.; Martynova, E.; Axenov-Gribanov, D.
10.1101/2024.07.03.601846 — developmental biology — Posted on 2024-07-06
4176 The functional roles of zebrafish HoxA- and HoxD-related clusters in the pectoral fin development
Ishizaka, M.; Nakazawa, H.; Maeno, A.; Kanno, H.; Fujii, R.; Tani, T.; Oikawa, S.; Koita, R.; Kawamura, A.
10.1101/2024.07.05.600788 — developmental biology — Posted on 2024-07-06
4177 Mapping the human hematopoietic stem and progenitor cell hierarchy through integrated single-cell proteomics and transcriptomics
Furtwaengler, B.; Uresin, N.; Richter, S.; Schuster, M. B.; Barmpouri, D.; Holze, H.; Wenzel, A.; Gronbaek, K.; Theilgaard-Moench, K.; Theis, F. J.; Schoof, E. M.; Porse, B. T.
10.1101/2024.07.05.602277 — cell biology — Posted on 2024-07-06
4181 Loss of TLR9 expression in breast cancer tumour cells and its role in the cell cycle.
Sible, E.; Weitsman, G.; Amouya, S.; Roblot, G.; Marotel, M.; Pescarmona, R.; Bendriss-Vermare, N.; Gillet, C.; Walzer, T.; Ceesay, A.; Michallet, M.-C.; Caux, C.; Cosset, F.-L.; Al-alem, U.; Ng, T.; Hasan, U. A.
10.1101/2024.07.04.601915 — cell biology — Posted on 2024-07-06
4182 Cellular heterogeneity in hypertrophic burn scars in response to carbon dioxide laser therapy
Chen, Y.-Y.; Mahon, C.; Turner, J.; Smith, C. M.; Abdulsalam, A.; Amirize, E.; Prince, A.; Heagerty, A.; Roberts, C.; Croft, A.; Wilson, Y.; Moiemen, N.; Lord, J.
10.1101/2024.07.05.600800 — cell biology — Posted on 2024-07-06
4183 Fully-Automated Multicolour Structured Illumination Module for Super-resolution Microscopy
Wang, H.; Peter, B.; Ullom, J.; Shepherd, D. P.; Heintzmann, R. P.; Diederich, B.
10.1101/2024.07.04.601961 — cell biology — Posted on 2024-07-06
4187 De novo synthesis of fatty acids in Archaea via an archaeal fatty acid synthase complex
Schmerling, C.; Zhou, X.; Goers, P. E.; Koestlbacher, S.; Kessenbrock, T.; Podlesainski, D.; Sybers, D.; Wang, K.; Lindas, A.-C.; Snoep, J. L.; Peeters, E.; Kaiser, M.; Ettema, T. J. G.; Meckelmann, S. W.; Braesen, C.; Siebers, B.
10.1101/2024.07.05.601840 — microbiology — Posted on 2024-07-06
4188 Transovarial transmission in field caught mosquitoes identifies a mechanism for the establishment of Usutu virus in a temperate country
Schilling, M.; Lawson, B.; Spiro, S.; Jagdev, M.; Vaux, A. G. C.; Bruce, R. C.; Johnston, C. J.; Abbott, A. J.; Wrigglesworth, E.; Pearce-Kelly, P.; Cunningham, A. A.; Medlock, J. M.; Johnson, N.; Folly, A. J.
10.1101/2024.07.05.602178 — microbiology — Posted on 2024-07-06
4189 Toxic Small Alarmone Synthetase FaRel2 inhibits translation by pyrophosphorylating tRNAGly and tRNAThr
Kurata, T.; Takegawa, M.; Ohira, T.; Syroegin, E. A.; Johansson, M. J. O.; Atkinson, G. C.; Polikanov, Y. S.; Garcia-Pino, A.; Suzuki, T.; Hauryliuk, V.
10.1101/2024.07.05.602228 — microbiology — Posted on 2024-07-06
4190 Surveillance of H5 HPAI in Michigan using retail milk
Lauring, A. S.; Martin, E. T.; Eisenberg, M. C.; Fitzsimmons, W. J.; Salzman, E.; Leis, A. M.; Lyon-Callo, S.; Bagdasarian, N.
10.1101/2024.07.04.602115 — microbiology — Posted on 2024-07-06
4193 Altered B Cell Metabolic Pathways Characterize Type 1 Diabetes Progression
Conway, H.; Perez, D.; Swar-Eldahab, M.; Pignanelli, J.; Evans-Molina, C.; Felton, J. L.
10.1101/2024.07.03.601778 — immunology — Posted on 2024-07-06
4194 A lasting impact of serotonergic psychedelics on visual processing and behavior
West, C. L.; Bastos, G.; Duran, A.; Nadeem, S.; Ricci, D. A.; Rader, A. M.; Wargo, J. A.; Peterka, D. S.; Van Leeuwen, N.; Hamm, J. P.
10.1101/2024.07.03.601959 — neuroscience — Posted on 2024-07-06
4196 Glia control experience-dependent plasticity in an olfactory critical period
Leier, H. C.; Foden, A. J.; Jindal, D. A.; Wilkov, A. J.; Van der Linden Costello, P.; Vanderzalm, P. J.; Coutinho-Budd, J.; Tabuchi, M.; Broihier, H. T.
10.1101/2024.07.05.602232 — neuroscience — Posted on 2024-07-06
4197 Molecular and cellular rhythms in excitatory and inhibitory neurons in the mouse prefrontal cortex
Burns, J. N.; Jenkins, A. K.; Yin, R.; Zong, W.; Vadnie, C. A.; DePoy, L.; Petersen, K. A.; Tsyglakova, M.; Scott, M. R.; Tseng, G.; Huang, Y. H.; McClung, C. A.
10.1101/2024.07.05.601880 — neuroscience — Posted on 2024-07-06
4198 Bayesian inference in arm posture perception
Peviani, V. C.; Joosten, M. G. A.; Miller, L. E.; Medendorp, W. P.
10.1101/2024.07.05.602180 — neuroscience — Posted on 2024-07-06
4199 Robustness of mitochondrial biogenesis and respiration explain aerobic glycolysis
Arunachalam, E.; Keber, F. C.; Law, R. C.; Kumar, C. K.; Shen, Y.; Park, J. O.; Wuehr, M.; Needleman, D. J.
10.1101/2024.07.04.601975 — systems biology — Posted on 2024-07-05
4201 Hormonal dynamics reveal a stimulatory role for secretoneurin in zebrafish ovulation
Peng, D.; Lu, C.; Spadacini, V.; Mitchell, K.; Tan, Y.; Zhang, D.; Levavi-Sivan, B.; Hu, W.; Trudeau, V.
10.1101/2024.07.03.601258 — physiology — Posted on 2024-07-05
4202 Agent-Based Modeling of Virtual Tumors Reveals the Critical Influence of Microenvironmental Complexity on Immunotherapy Efficacy
Wang, Y.; Bergman, D. R.; Trujillo, E.; Fernald, A. A.; Li, L.; Pearson, A. T.; Sweis, R. F.; Jackson, T. L.
10.1101/2024.07.03.601920 — cancer biology — Posted on 2024-07-05
4204 Translational control of cell plasticity drives 5-FU tolerance
CHALABI-DCHAR, M.; VILLERONCE, O.; RIPOLL, J.; VINCENT, A.; FENOUIL, T.; KHOUEIRY, R.; KUCHARCZAK, J.; JENTSCHEL, L.; CATEZ, F.; Vigneron, A. M.; TREGUIER, J.; MANDIER, C.; BOUCLIER, C.; VITRE, J.; LAGERQVIST, L.; CHOQUET, A.; HERCEG, Z.; MACHON, C.; GUITTON, J.; DAVID, A.; SOLARY, E.; Bernard, D.; MARTIN, N.; RIVALS, E.; DALLA VENEZIA, N.; Pannequin, J.; DIAZ, J.-J.
10.1101/2024.07.03.601826 — cancer biology — Posted on 2024-07-06
4207 Mechanism of Proton Release during Water Oxidation in Photosystem II
Allgower, F.; Poverlein, M. C.; Rutherford, A. W.; Kaila, V. R. I.
10.1101/2024.07.03.602004 — biophysics — Posted on 2024-07-06
4208 Identifying Alzheimer's disease-related pathways based on whole-genome sequencing data
Wang, Y.; Liu, T.; He, Y.; Tang, Y.; Tan, P.; Huang, L.; Huang, D.; Wen, T.; Shao, L.; Wang, J.; Wang, Y.; Han, Z.
10.1101/2024.07.03.601830 — bioinformatics — Posted on 2024-07-05
4211 Setting up an institutional OMERO environment for bioimage data: perspectives from both facility staff and users
Jannasch, A. K.; Tulok, S.; Okafornta, C. W.; Kugel, T.; Bortolomeazzi, M.; Boissonnet, T.; Schmidt, C.; Vogelsang, A.; Dittfeld, C.; Tugtekin, S.-M.; Matschke, K. E.; Paliulis, L.; Lindemann, D.; Fabig, G.; Mueller-Reichert, T.
10.1101/2024.07.04.601832 — bioinformatics — Posted on 2024-07-06
4214 Oriented nucleosome binding by the pioneer factor ELF2
Xiao, T.; Crowe-McAuliffe, C.; Ochmann, M.; Zhu, F.; Osmala, M.; Rogerson, C.; Cramer, P.; Dienemann, C.; Taipale, J.
10.1101/2024.05.24.595749 — biochemistry — Posted on 2024-07-05
4216 Structural details of helix-mediated TDP-43 C-terminal domain multimerization
Rizuan, A.; Shenoy, J.; Mohanty, P.; dos Passos, P. M.; Mercado Ortiz, J. F.; Bai, L.; Viswanathan, R.; Wang, S.-H.; Johnson, V.; Mamede, L. D.; Ayala, Y. M.; Ghirlando, R.; Mittal, J.; Fawzi, N. L.
10.1101/2024.07.05.602258 — biochemistry — Posted on 2024-07-06
4218 High-Resolution Multimodal Profiling of Human Epileptic Brain Activity via Explanted Depth Electrodes
Dwivedi, A.; Mariappan, A.; Sanfeliu, A.; Larkin, J.; Walsh, P.; Henshall, D.; Tiwari, V.
10.1101/2024.07.03.601925 — genomics — Posted on 2024-07-05
4220 Discovery of a novel albendazole-ivermectin refractory Trichuris species, T. hominis, in Côte d'Ivoire patients through fecal DNA metabarcoding
Venkatesan, A.; Chen, R.; Bär, M. A.; Schneeberger, P.; Reimer, B.; Hürlimann, E.; Coulibaly, J. T.; Ali, S. M.; Sayasone, S.; Soghigian, J.; Keiser, J.; Gilleard, J. S.
10.1101/2024.07.04.602123 — genomics — Posted on 2024-07-06
4222 Pan-cancer subclonal mutation analysis of 7,827 tumors predicts clinical outcome
Jiang, Y.; Montierth, M. D.; Yu, K.; Ji, S.; Guo, S.; Tran, Q.; Liu, X.; Shin, S. J.; Cao, S.; Li, R.; Tang, Y.; Lesluyes, T.; Kopetz, S.; Ajani, J.; Msaouel, P.; Subudhi, S. K.; Aparicio, A.; Sharma, P.; Shen, J. P.; Sood, A. K.; Tarabichi, M.; Wang, J. R.; Kimmel, M.; Loo, P. V.; Zhu, H.; Wang, W.
10.1101/2024.07.03.601939 — genomics — Posted on 2024-07-06
4225 Evaluating UCE data adequacy and integrating uncertainty in a comprehensive phylogeny of ants
Borowiec, M. L.; Zhang, Y. M.; Neves, K.; Ramahlo, M. O.; Fisher, B. L.; Lucky, A.; Moreau, C. S.
10.1101/2024.07.03.601921 — evolutionary biology — Posted on 2024-07-05
4227 Copy number variation contributes to parallel local adaptation in an invasive plant
Wilson, J. R.; Battlay, P.; Bieker, V. C.; van Boheemen, L.; Connallon, T.; Martin, M. D.; Hodgins, K. A.
10.1101/2024.07.03.601998 — evolutionary biology — Posted on 2024-07-06
4241 Mass Spectrometry-based Profiling of Single-cell Histone Post-translational Modifications to Dissect Chromatin Heterogeneity
Cutler, R.; Corveleyn, L.; Ctortecka, C.; Cantlon, J.; Jacome Vaca, S. A.; Deforce, D.; Vijg, J.; Dhaenens, M.; Papanastasiou, M.; Carr, S. A.; Sidoli, S.
10.1101/2024.07.05.602213 — molecular biology — Posted on 2024-07-06
4248 TLR9 signaling requires ligand-induced phosphorylation of two specific tyrosine residues by EGFR and Syk
Veleeparambil, M.; Wang, C.; Kessler, P. M.; Willard, B.; Sen, G. C.; Chattopadhyay, S.
10.1101/2024.07.03.601759 — immunology — Posted on 2024-07-05
4249 Whole-body PET imaging of SIV using anti-Env probes fails to reveal regions of specific uptake in rhesus macaques
Srinivasula, S.; Kim, I.; Jang, H.; DeGrange, P.; Brown, H.; Dalton, V.; Badralmaa, Y.; Natarajan, V.; Long, B.; Carrasquillo, J.; Di Mascio, M.
10.1101/2024.07.05.601545 — immunology — Posted on 2024-07-05
4250 Wild-type and single-O-antigen repeat outer-membrane vesicles induce equivalent protection against homologous and heterologous Salmonella challenge
Alshayea, A. I.; Jossi, S.; Marcial-Juarez, E.; Perez-Toledo, M.; Persaud, R.; Schager, A. E.; Larsen, D. N.; Gutishvili, G.; Pillaye, J.; Escobar-Riquelme, F.; Aksu, K.; Bryant, J. A.; Horsnell, W. G.; Banzhaf, M.; Kaczmarek, J. Z.; Hojrup, P.; C. Gumbart, J.; Henderson, I. R.; Bavro, V. N.; Lopez-Macias, C.; Cunningham, A. F.
10.1101/2024.07.03.601871 — immunology — Posted on 2024-07-05
4251 Bacterial vaginosis-driven changes in vaginal T cell phenotypes and their implications for HIV susceptibility
MacLean, F.; Tsegaye, A. T.; Graham, J. B.; Swarts, J. L.; Vick, S. C.; Potchen, N.; Cruz Talavera, I.; Warrier, L.; Dubrulle, J.; Schroeder, L. K.; Mar, C.; Thomas, K. K.; Mack, M.; Sabo, M. C.; Chohan, B. H.; Ngure, K.; Mugo, N.; Lingappa, J. R.; Lund, J. M.
10.1101/2024.07.03.601916 — immunology — Posted on 2024-07-05
4252 Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation channels
Giese, A. P. J.; Weng, W.-H.; Kindt, K. S.; Chang, V. H. H.; Montgomery, J. S.; Ratzan, E. M.; Beirl, A. J.; Aponte Rivera, R.; Lotthammer, J. M.; Walujkar, S.; Foster, M. P.; Zobeiri, O. A.; Holt, J. R.; Riazuddin, S.; Cullen, K. E.; Sotomayor, M.; Ahmed, Z. M.
10.1101/2023.05.26.542533 — neuroscience — Posted on 2024-07-05
4253 Poor Self-Reported Sleep is Associated with Prolonged White Matter T2 Relaxation in Psychotic Disorders
Yesilkaya, H. U.; Chen, X.; Watford, L.; McCoy, E.; Genc, I.; Du, F.; Ongur, D.; Yuksel, C.
10.1101/2024.07.03.601887 — neuroscience — Posted on 2024-07-05
4256 An orbitocortical-thalamic circuit suppresses binge alcohol-drinking.
Gimenez Gomez, P.; Le, T.; Zinter, M.; M'angale, P.; Duran Laforet, V.; Freels, T.; Pavchinskiy, R.; Molas, S.; Schafer, D.; Tapper, A.; Thomson, T.; Martin, G.
10.1101/2024.07.03.601895 — neuroscience — Posted on 2024-07-05
4257 Simultaneous dual-color calcium imaging in freely-behaving mice
Dong, Z.; Feng, Y.; Diego, K.; Baggetta, A. M.; Sweis, B. M.; Pennington, Z. T.; Lamsifer, S. I.; Zaki, Y.; Sangiuliano, F.; Philipsberg, P. A.; Morales-Rodriguez, D.; Kircher, D. M.; Slesinger, P.; Shuman, T.; Aharoni, D.; Cai, D. J.
10.1101/2024.07.03.601770 — neuroscience — Posted on 2024-07-05
4260 Hierarchical cortical plasticity in congenital sight impairment
Maimon-Mor, R. O.; Farahbakhsh, M.; Hedger, N.; Rider, A. T.; Anderson, E.; Rees, G.; Knapen, T.; Michaelides, M.; Dekker, T.
10.1101/2024.07.04.602138 — neuroscience — Posted on 2024-07-05
4263 Atypical chemokine receptor 3 regulates synaptic removal in disease astrocytes
Giusti, V.; Park, J.; Giusto, E.; Masatti, L.; Ramos-Gonzales, P.; Iovino, L.; Sandre, M.; Emmi, A.; Kaur, G.; Coletto, E.; Calura, E.; Petrelli, F.; Porzionato, A.; De Caro, R.; Cavaliere, F.; Civiero, L.
10.1101/2024.07.03.601867 — neuroscience — Posted on 2024-07-05
4265 Postprandial sleep in short-sleeping Mexican cavefish
Gallman, K.; Rastoge, A.; North, O.; O'Gorman, M.; Hutton, P.; Lloyd, E.; Warren, W. C.; Kowalko, J. E.; Duboue, E. R.; Rohner, N.; Keene, A. C.
10.1101/2024.07.03.602003 — neuroscience — Posted on 2024-07-05
4266 Simulating a medical expertise: a robust novel stress induction paradigm in chronic pain patients
Chiron, A.; Fernandez, A.; Schmidt, L.; Plaza Wuthrich, S.; Suter, M. R.; Leknes, S.; Berna, C.
10.1101/2024.07.03.601919 — neuroscience — Posted on 2024-07-05
4270 Taxonomy and nomenclature of the giant hummingbirds (Patagona spp.) (Aves: Trochilidae)
Williamson, J. L.; Gadek, C. R.; Robinson, B. W.; Bautista, E.; Bauernfeind, S. M.; Baumann, M. J.; Gyllenhaal, E. F.; Marra, P. P.; Ricote, N.; Singh, N. D.; Valqui, T.; Witt, C. C.
10.1101/2024.07.03.601580 — zoology — Posted on 2024-07-05
4271 Life Cycle and Morphogenetic Differentiation in Heteromorphic Cell Types of a Cosmopolitan Marine Microalga
Bousquet, L.; Fainsod, S.; Decelle, J.; Murik, O.; Chevalier, F.; Gallet, B.; Templin, R.; Schwab, Y.; Avrahami, Y.; Koplovitz, G.; Ku, C.; Frada, M.
10.1101/2024.07.03.601694 — plant biology — Posted on 2024-07-05
4274 Basal Cambrian soft-bodied segmented bilaterians preserved as microbial pseudomorphs
Yang, X.; Wang, D.; Zhang, Z.; Wang, X.; Sun, J.; Hao, W.; Liu, Y.; Uesugi, K.; Komiya, T.; Han, J.
10.1101/2024.07.03.601876 — paleontology — Posted on 2024-07-05
4275 Aging promotes lung cancer metastasis through epigenetic ATF4 induction
Patel, A. A. H.; Dzanan, J.; Ali, K. X.; Eklund, E. A.; Alvarez, S. W.; Altinönder, I.; Raj, D.; Zowalaty, A. E. E.; Sayin, S. I.; Dankis, M.; Schwarz, M.; Jonasson, E.; Le Gal, K.; Albatrok, H.; Oloffson Bagge, R.; Härtlova, A.; Stahlberg, A.; Hallqvist, A.; Wiel, C.; Sayin, V. I.
10.1101/2024.07.03.601209 — cancer biology — Posted on 2024-07-05
4276 Microgravity stimulates network activity of 3D neuronal spheroids in an acoustic trap
Lecoq, P.-E.; Viraye, G.; Dupuis, C.; Benoit-Gonin, X.; Aider, J.-L.; Peyrin, J.-M.
10.1101/2024.07.03.601873 — biophysics — Posted on 2024-07-05
4278 PEPCy: Photostable fluoromodules for live cell, super-resolution microscopy of surface proteins
Sasazawa, M.; Chimthanawala, A.; Zeng, R.; Kim, D.; Buchan, K.; Zhang, M.; Saurabh, S.
10.1101/2024.07.03.601615 — biophysics — Posted on 2024-07-05
4281 Spatial top-down proteomics for the functional characterization of human kidney
Zemaitis, K. J.; Fulcher, J. M.; Kumar, R.; Degnan, D. J.; Lewis, L. A.; Liao, Y.-C.; Velickovic, M.; Williams, S. M.; Moore, R. J.; Bramer, L. M.; Velickovic, D.; Zhu, Y.; Zhou, M.; Pasa-Tolic, L.
10.1101/2024.02.13.580062 — biochemistry — Posted on 2024-07-05
4282 From Acute to Persistent Infection: Revealing Phylogenomic Variations in Salmonella Agona
Waters, E. V.; Lee, W. W. Y.; Ismail Ahmed, A.; Chattaway, M.-A.; Langridge, G. C.
10.1101/2024.07.03.601855 — genomics — Posted on 2024-07-05
4284 Characterization of diatom communities in restored sewage channels in the Boye catchment, Germany
Mayombo, N. A. S.; Haverbeck, L. S.; Dani, M.; Kloster, M.; Vidakovic, D.; Beszteri, B.; Burfeid-Castellanos, A. M.
10.1101/2024.07.03.601863 — ecology — Posted on 2024-07-05
4285 Torque Teno Sus Virus 1: A Potential Surrogate Pathogen to Study Pig-Transmitted Transboundary Animal Diseases
Li, X.; Parker, B.; Boughton, R.; Beasley, J.; Smyser, T. J.; Austin, J.; Pepin, K.; Miller, R. S.; VerCauteren, K. C.; Wisely, S. M.
10.1101/2024.07.03.601911 — ecology — Posted on 2024-07-05
4286 Substrate stiffness modulates the emergence and magnitude of senescence phenotypes in dermal fibroblasts
Starich, B.; Yang, F.; Tanrioven, D.; Kung, H.-C.; Baek, J.; Nair, P. R.; Kamat, P.; Macaluso, N.; Eoh, J.; Han, K. S.; Gu, L.; Walston, J.; Sun, S.; Wu, P.-H.; Wirtz, D.; Phillip, J. M.
10.1101/2024.02.06.579151 — molecular biology — Posted on 2024-07-05
4287 Pathophysiology of hypereosinophilia-associated heart disease
Sunusi, U.; Ziegelmeyer, B.; Osuji, I.; Medvedovic, M.; Todd, H.; Abou-Khalil, J.; Zimmermann, N.
10.1101/2024.07.03.601845 — immunology — Posted on 2024-07-05
4288 Neurocomputational Mechanisms Underlying Maladaptive Self-Belief Formation in Depression
Czekalla, N.; Schröder, A.; Mayer, A. V.; Stierand, J.; Stolz, D. S.; Kube, T.; Korn, C. W.; Wilhelm-Groch, I.; Klein, J. P.; Paulus, F. M.; Krach, S.; Müller-Pinzler, L.
10.1101/2024.05.09.593087 — neuroscience — Posted on 2024-07-05
4289 Sex differences in change-of-mind neuroeconomic decision-making is modulated by LINC00473 in medial prefrontal cortex
Durand-de Cuttoli, R.; Issler, O.; Yakubov, B.; Jahan, N.; Abid, A.; Kasparov, S.; Granizo, K.; Ahmed, S.; Russo, S. J.; Nestler, E. J.; Sweis, B. M.
10.1101/2024.05.08.592609 — neuroscience — Posted on 2024-07-05
4291 Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology
Goettemoeller, A. M.; Banks, E.; Kumar, P.; Olah, V. J.; McCann, K. E.; South, K.; Ramelow, C. C.; Eaton, A.; Duong, D. M.; Seyfried, N. T.; Weinshenker, D.; Rangaraju, S.; Rowan, M. J.
10.1101/2023.11.06.565629 — neuroscience — Posted on 2024-07-05
4292 Flexible neural representations of abstract structural knowledge in the human Entorhinal Cortex
Mark, S.; Baram, A.; Schwartenbeck, P.; Hahamy, A.; Samborska, V.; Behrens, T. E. J.
10.1101/2023.08.31.555760 — neuroscience — Posted on 2024-07-05
4294 Niche-Based Priority Effects Predict Microbe Resistance to Erwinia amylovora in Pear Nectar
McDaniel, C. S.; Vannette, R. L.; Arroyo-Flores, A.; Boundy-Mills, K. L.; Crowder, D. W.; Grilley, M. M.; Pathak, H.; Schaeffer, R. N.
10.1101/2024.07.03.601912 — plant biology — Posted on 2024-07-05
4296 Methods for constructing and evaluating consensus genomic interval sets
Rymuza, J.; Sun, Y.; Zheng, G.; LeRoy, N. J.; Murach, M.; Phan, N.; Zhang, A.; Sheffield, N. C.
10.1101/2023.08.03.551899 — genomics — Posted on 2024-07-05
4297 ZIP13 regulates lipid metabolism by changing intracellular iron and zinc balance
Fukunaka, A.; Tanaka, G.; Kimura, T.; Hengphasatporn, K.; Saito, D.; Shigeta, M.; Shibata, H.; Ichinose, T.; Abe, I.; Shimura, M.; Sato, T.; Nakagawa, Y.; Horii, T.; Hatada, I.; Kajimura, S.; Kiyonari, H.; Sakurai, H.; Shigeta, Y.; Watada, H.; Fukada, T.; Fujitani, Y.
10.1101/2024.07.03.601606 — cell biology — Posted on 2024-07-05
4299 Neonatal microbiota colonization drives maturation of primary and secondary goblet cell mediated protection in the pre-weaning colon
Johansson, A.; Venkita Subramani, M.; Yilmaz, B.; Nystrom, E.; Layunta, E.; Arike, L.; Sommer, F.; Rosenstiel, P.; Vereecke, L.; Manneras Holm, L.; Wullaert, A.; Pelaseyed, T.; Johansson, M. E. V.; Birchenough, G. M. H.
10.1101/2024.07.03.601781 — immunology — Posted on 2024-07-05
4300 Autoregulation of cluster root and nodule development by white lupin CCR1 receptor-like kinase
Marques, L.; Divol, F.; Boultif, A.; Garcia, F.; Soriano, A.; Maurines-Carboneill, C.; Fernandez, V.; Verstraeten, I.; Pidon, H.; Izquierdo, E.; Hufnagel, B.; Peret, B.
10.1101/2024.07.04.602037 — plant biology — Posted on 2024-07-05
4302 CarboTag: a modular approach for live and functional imaging of plant cell walls
Besten, M.; Hendriksz, M.; Michels, L.; Charrier, B.; Smakowska-Luzan, E.; Weijers, D.; Borst, J. W.; Sprakel, J.
10.1101/2024.07.05.597952 — plant biology — Posted on 2024-07-05
4303 Structurally diverse calloses/β-1,3-glucans in plant cell wall microdomains
Amsbury, S.; Marcus, S. E.; Yeshvekar, R.; Barber, J.; German, L.; Ross, J. F.; Lelenaite, I.; de Souza Moraes, T.; Wickramanayake, J.; Klebanovych, A.; Czymmek, K.; Burch-Smith, T. M.; Bayer, E. M.; Willats, W.; Manfield, I. W.; Knox, P.; Benitez-Alfonso, Y.
10.1101/2024.07.04.602027 — plant biology — Posted on 2024-07-05
4304 MAP4K1 and MAP4K2 regulate ABA-induced and Ca2+-mediated stomatal closure in Arabidopsis
Yamashita, K.; Katagiri, S.; Takase, H.; Li, Y.; Otoguro, A.; Kamiyama, Y.; Yamauchi, S.; Takemiya, A.; Mori, I. C.; Umezawa, T.
10.1101/2024.07.05.602132 — plant biology — Posted on 2024-07-05
4305 Integrating Gene Expression Analysis and Ecophysiological Responses to Water Deficit in Leaves of Tomato Plants
Bortolami, G.; de Werk, T. A.; Larter, M.; Thonglim, A.; Mueller-Roeber, B.; Balazadeh, S.; Lens, F.
10.1101/2024.07.05.602262 — plant biology — Posted on 2024-07-05
4306 Spatial Transcriptomics Reveals a Myeloma Cell Architecture with Dysfunctional T-Cell Distribution, Neutrophil Traps, and Inflammatory Signaling
Sudupe, L.; Muinos-Lopez, E.; Lopez-Perez, A. R.; Vilas-Zornoza, A.; Sarvide, S.; Ripalda-Cemborain, P.; Aguirre-Ruiz, P.; San Martin-Uriz, P.; Larrayoz, M.; Alvarez-Gigli, L.; Abengozar-Muela, M.; Cenzano, I.; Cocera, M.; Ruiz, J.; Sancho Gonzalez, I.; Bantan, A.; Kurowska, A.; Ye, J.; Newton, P. T.; Paiva, B.; Rodriguez-Madoz, J. R.; Lagani, V.; tegner, j.; Saez, B.; Martinez-Climent, J. A.; Calvo Arnedo, I.; Gomez-Cabrero, D.; Prosper, F.
10.1101/2024.07.03.601833 — cancer biology — Posted on 2024-07-05
4307 Alzheimer Disease Knowledge Graph Enhances Knowledge Discovery and Disease Prediction
Yang, Y.; Zhu, H.; Yu, K.; Gao, S.; Yu, S.; Xiong, D.; Qin, C.; Chen, H.; Tang, J.; Tang, N.
10.1101/2024.07.03.601339 — bioinformatics — Posted on 2024-07-05
4310 UPF1 is required for gene expression in mitochondria and paternal mtDNA clearance during spermatogenesis
Wright, M. T.; Singh, A. K.; Dixon, H. L.; Price, E. M.; Connolly, E. C.; di Maio, A.; Barlow, J. P.; Catoni, M.; Fan, Y.; Brogna, S.
10.1101/2024.05.10.591322 — cell biology — Posted on 2024-07-05
4314 Exceptional longevity of mammalian ovarian and oocyte macromolecules throughout the reproductive lifespan
Bomba-Warczak, E. K.; Velez, K. M.; Zhou, L. T.; Guillermier, C.; Edassery, S.; Steinhauser, M. L.; Savas, J. N.; Elizabeth Duncan, F.
10.1101/2023.10.18.562852 — physiology — Posted on 2024-07-05
4319 Unique territorial and compartmental organization of chromosomes in the holocentric silkmoth
Gil, J.; Rosin, L. F.; Navarrete, E.; Chowdhury, N.; Abraham, S.; Cornilleau, G.; Lei, E. P.; Mozziconacci, J.; Mirny, L. A.; Muller, H.; Drinnenberg, I. A.
10.1101/2023.09.14.557757 — genomics — Posted on 2024-07-05
4324 Intercellular adhesion boots collective cell migration through elevated membrane tension
Bijonowski, B. M.; Park, J.; Bergert, M.; Teubert, C.; Diz-Munoz, A.; Galic, M.; Wegner, S. V.
10.1101/2024.07.03.601828 — cell biology — Posted on 2024-07-05
4327 Glomerular Elasticity and Gene Expression Patterns Define Two Phases of Alport Nephropathy
Yoon, J.; Liu, Z.; Alaba, M.; Bruggeman, L. A.; Janmey, P.; Arana, C.; Ayenuyo, O.; Medeiros, I.; Nair, V.; Eddy, S.; Kretzler, M.; Henderson, J. M.; Naik, A.; Chang, A. N.; Miller, R. T.
10.1101/2024.02.26.582201 — cell biology — Posted on 2024-07-05
4331 Harnessing early multimodal motor training to drive motor recovery and brain-wide structural reorganization after stroke
Teichert, M.; Gull, S.; Herrmann, K.-H.; Gaser, C.; Reichenbach, J. R.; Urbach, A.; Frahm, C.; Holthoff, K.; Witte, O. W.; Schmidt, S.
10.1101/2024.07.03.601837 — neuroscience — Posted on 2024-07-05
4333 Restoration of locus coeruleus noradrenergic transmission during sleep
Sima, J.; Zhang, Y.; Farriday, D.; Ahn, A. Y.-E.; Lopez, E. R.; Jin, C.; Harrell, J.; Darmohray, D.; Silverman, D.; Dan, Y.
10.1101/2024.07.03.601820 — neuroscience — Posted on 2024-07-05
4335 An Alzheimer's disease-associated common regulatory variant in a PTK2B intron alters microglial function
Bello, E.; Long, K.; Iwama, S.; Steer, J.; Cooper, S. E.; Alasoo, K.; Kumasaka, N.; Schwartzentruber, J.; Panousis, N. I.; Bassett, A. R.
10.1101/2023.11.04.565613 — neuroscience — Posted on 2024-07-05
4337 A murine experimental model of the unique pulmonary thrombotic effect induced by the venom of the snake Bothrops lanceolatus
Rucavado, A.; Camacho, E.; Escalante, T.; Lomonte, B.; Fernandez, J.; Solano, D.; Quiros-Gutierrez, I.; Ramirez-Vargas, G.; Vargas, K.; Arguello, I.; Navarro, A.; Abarca, C.; Segura, A.; Florentin, J.; Kallel, H.; Resiere, D.; Neviere, R.; Gutierrez, J. M.
10.1101/2024.07.03.601850 — pharmacology and toxicology — Posted on 2024-07-05
4338 Mechanobiochemical finite element model to analyze impact-loading-induced cell damage, subsequent proteoglycan loss, and anti-oxidative treatment effects in articular cartilage
Kosonen, J. P.; Eskelinen, A. S. A.; Orozco, G. A.; Coleman, M. C.; Goetz, J. E.; Anderson, D. D.; Grodzinsky, A. J.; Tanska, P.; Korhonen, R. K.
10.1101/2024.07.03.601852 — biophysics — Posted on 2024-07-05
4340 Dicarbonyl stress enhances tumor intravasation
Kumar, N.; Samanta, B.; M, J. K.; Raghunathan, V.; Sen, P.; Bhat, R.
10.1101/2024.07.03.601810 — bioengineering — Posted on 2024-07-05
4341 Mapping the blood vasculature in an intact human kidney using hierarchical phase-contrast tomography
Rahmani, S.; Jafree, D. J.; Lee, P. D.; Tafforeau, P.; Brunet, J.; Nandawar, S.; Jacob, J.; Bellier, A.; Ackermann, M.; Jonigk,, D. D.; Shipley, R. J.; Long, D. A.; Walsh, C. L.
10.1101/2023.03.28.534566 — bioengineering — Posted on 2024-07-05
4346 Structure-based inference of eukaryotic complexity in Asgard archaea
Koestlbacher, S.; van Hooff, J. J. E.; Panagiotou, K.; Tamarit, D.; De Anda, V.; Appler, K. E.; Baker, B. J.; Ettema, T. J. G.
10.1101/2024.07.03.601958 — evolutionary biology — Posted on 2024-07-05
4349 Polyelectrolyte mannan from diatoms reshapes sunlit ocean microbiome
Krull, J.; Crawford, C. J.; Sidhu, C.; Solanki, V.; Bligh, M.; Rössler, L.; Singh, R. K.; Huang, G.; Robb, C. S.; Teeling, H. J.; Seeberger, P. H.; Schweder, T.; Hehemann, J.-H.
10.1101/2024.07.03.601839 — ecology — Posted on 2024-07-05
4352 UltraCortex: Submillimeter Ultra-High Field 9.4 T Brain MR Image Collection and Manual Cortical Segmentations
Mahler, L.; Steiglechner, J.; Bender, B.; Lindig, T.; Ramadan, D.; Bause, J.; Birk, F.; Heule, R.; Charyasz, E.; Erb, M.; Kumar, V. J.; Hagberg, G. E.; Martin, P.; Lohmann, G.; Scheffler, K.
10.1101/2024.06.18.599541 — neuroscience — Posted on 2024-07-05
4354 Full-length RNA transcript sequencing traces brain isoform diversity in house mouse natural populations
Zhang, W.; Guenther, A.; Gao, Y.; Ullrich, K. K.; Huettel, B.; Ahmad, A.; Duan, L.; Wei, K.; Tautz, D.
10.1101/2024.01.03.573993 — genomics — Posted on 2024-07-05
4355 ASTROGLIOSIS AND NEUROINFLAMMATION UNDERLIE SCOLIOSIS UPON CILIA DYSFUNCTION
Djebar, M.; Anselme, I.; Pezeron, G.; Bardet, P.-L.; Cantaut-Belarif, Y.; Eschstruth, A.; Lopez-Santos, D.; Le Ribeuz, H.; Jenett, A.; Khoury, H.; Veziers, J.; Parmentier, C.; Hirschler, A.; Carapito, C.; Bachmann-Gagescu, R.; Schneider-Maunoury, S.; Vesque, C.
10.1101/2024.02.22.581530 — developmental biology — Posted on 2024-07-05
4356 Inhibition of the Notch signal transducer CSL by Pkc53E-mediated phosphorylation to fend off parasitic immune challenge in Drosophila
Deichsel, S.; Frankenreiter, L.; Fechner, J.; Gahr, B. M.; Zimmermann, M.; Mastel, H.; Preis, I.; Preiss, A.; Nagel, A. C.
10.1101/2023.06.16.545247 — developmental biology — Posted on 2024-07-05
4357 Placental malaria is associated with a TLR-Endothelin-3-oxidative damage response in human placenta tissues
Chenge, S.; Mbalitsi, M.; Ngure, H.; Obimbo, M.; Singoei, M.; Kangogo, M.; Kanoi, B. N.; Gitaka, J.; Kobia, F. M.
10.1101/2024.04.17.589949 — cell biology — Posted on 2024-07-05
4358 Inhibition of host N-myristoylation compromises the infectivity of SARS-CoV-2 due to Golgi-bypassing egress from lysosomes and endoplasmic reticulum
Saber, S. H.; Shaker, M. R.; Sng, J.; Yak, N.; Morrison, S. D.; Pars, S.; Zheng, H.; Pietrogrande, G.; Binder, T.; Lu, S.; Floetenmeyer, M.; Ojha, R.; Quirin, T.; Ruuska, J.; Smura, T.; Strandin, T.; Kant, R.; Kareinen, L.; Sironen, T.; Talbo, G. H.; Zhu, Y.; Short, K.; Mar, J. C.; Kallemeijn, W. W.; Tate, E. W.; Solari, R.; van Waardenberg, A. J.; Vapalahti, O.; Wolvetang, E. J.; Balistreri, G.; Joensuu, M.
10.1101/2023.03.03.530798 — microbiology — Posted on 2024-07-05
4359 Architecture of the Human Default Mode Network: Cytoarchitecture, Wiring and Signal Flow
Paquola, C.; Garber, M.; Fraessle, S.; Royer, J.; Zhou, Y.; Tavakol, S.; Rodriguez-Cruces, R.; Cabalo, D. G.; Valk, S. L.; Eickhoff, S.; Margulies, D. S.; Evans, A. C.; Amunts, K.; Jefferies, E.; Smallwood, J.; Bernhardt, B.
10.1101/2021.11.22.469533 — neuroscience — Posted on 2024-07-05
4360 Reconfiguration of the visual code and retinal cell type complement in closely related diurnal and nocturnal mice
Allen, A. E.; Hahn, J.; Richarson, R.; Pantiru, A.; Mouland, J.; Bano-Otalora, B.; Monavarfeshani, A.; Yan, W.; Williams, C.; Wynne, J.; Rodgers, J.; Milosavljevic, N.; Orlowska-Feuer, P.; Storchi, R.; Sanes, J. R.; Shekhar, K.; Lucas, R. J.
10.1101/2024.06.14.598659 — neuroscience — Posted on 2024-07-05
4362 Visualizing the translation landscape in human cells at high resolution
Zheng, W.; Zhang, Y.; Wang, J.; Wang, S.; Chai, P.; Bailey, E. J.; Guo, w.; Devarkar, S. C.; Wu, S.; Lin, J.; Zhang, K.; Liu, J.; Lomakin, I. B.; Xiong, Y.
10.1101/2024.07.02.601723 — molecular biology — Posted on 2024-07-05
4363 Inhibition of influenza virus replication by artificial proteins (αReps) targeting its RNA-polymerase
Delmas, B.; Bessonne, M.; Morel, J.; Nevers, Q.; Urvoas, A.; Valerio-Lepiniec, M.; Crepin, T.; Minard, P.
10.1101/2024.07.03.601934 — microbiology — Posted on 2024-07-05
4364 The archaeal class Nitrososphaeria is a key player of the reproductive microbiome in sponges during gametogenesis
Turon, M.; Koutsouveli, V.; Conejero, M.; Taboada, S.; Verdes, A.; Lorente-Sorolla, J. M.; Diez-Vives, C.; Riesgo, A.
10.1101/2024.07.03.601946 — microbiology — Posted on 2024-07-05
4365 MYBPHL nonsense mutations have poor sarcomere binding, are degraded, and cause abnormal contraction
Alvarez-Arce, A.; Fritzmann, G.; Burnham, H.; Araujo, K.; Pena, A.; Wittenkeller, L.; Barefield, D. Y.
10.1101/2024.07.01.601577 — physiology — Posted on 2024-07-05
4366 Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium
Medina-Feliciano, J. G.; Valentin-Tirado, G.; Luna-Martinez, K.; Miranda-Negron, Y.; Garcia-Arraras, J. E.
10.1101/2024.07.01.601561 — developmental biology — Posted on 2024-07-05
4367 YAP1 Contributes to The Development of Contractile Force and Sarcomere Maturation in Human Pluripotent Stem Cell Derived Cardiomyocytes
Vinarsky, V.; Pagliari, S.; Martino, F.; Mazzotti, C.; Jirakova, K.; Garlikova, Z.; Di Iuri, E.; Kytyr, D.; Benzoni, P.; Arici, M.; Metallo, A.; Zeevaert, K.; Wagner, W.; Rocchetti, M.; Forte, G.
10.1101/2024.07.02.601803 — cell biology — Posted on 2024-07-05
4368 Spatial transcriptomics unveils the in situ cellular and molecular hallmarks of the lung in fatal COVID-19
Garcia-Prieto, C.; Musulen, E.; Davalos, V.; Ferrer, G.; Grases, D.; Porta-Pardo, E.; Perez Mies, B.; Caniego Casas, T.; Palacios, J.; Saenz Sarda, X.; Englund, E.; Esteller, M.
10.1101/2024.07.03.601404 — pathology — Posted on 2024-07-04
4371 Female fruit flies use social cues to make egg clustering decisions
Churchill, E. R.; Fowler, E. K.; Friend, L. A.; Archetti, M.; Yu, D. W.; Bourke, A. F. G.; Chapman, T.; Bretman, A.
10.1101/2024.07.03.600353 — animal behavior and cognition — Posted on 2024-07-05
4372 Revisiting the impact of synthetic ORF sequences on engineered LINE-1 retrotransposition
Chan, D.; Workman, S.; Gerdes, P.; Han, J. S.; Boeke, J. D.; Faulkner, G. J.; Richardson, S. R.
10.1101/2022.08.29.505632 — molecular biology — Posted on 2024-07-04
4374 Pathogenic Th17 cells in ZAP-70 mutant mice share T cell receptor features with Wild-type Tregs
Llamas-Covarrubias, M. A.; Tanaka, A.; Loza Lopez, M. d. J.; Diez, D.; Xu, Z.; Lim, E. L.; Teraguchi, S.; Sakaguchi, S.; Standley, D. M.
10.1101/2024.03.01.582868 — immunology — Posted on 2024-07-04
4375 The Geometry and Dimensionality of Brain-wide Activity
Wang, Z.; Mai, W.; Chai, Y.; Qi, K.; Ren, H.; Shen, C.; Zhang, S.; Tan, G.; Hu, Y.; Wen, Q.
10.1101/2023.02.23.529673 — neuroscience — Posted on 2024-07-04
4376 Neurovascular coupling actively regulates context-dependent emotional adjustment
Ruan, J.; Quan, X.; Xie, H.; Zhang, Y.; Zhang, D.; Wang, W.; Zhao, B.; Lu, D.; Jia, J.-M.
10.1101/2023.02.13.527949 — neuroscience — Posted on 2024-07-04
4377 Mesolimbic local field potentials are modulated by motor control
Mann, L. G.; Qian, H.; Hughes, N. C.; Zhao, Z.; Singh, B.; Wang, Z.; Johnson, G. W.; Fulton, J. N.; Yan, B.; Kang, H.; Li, R.; Dawant, B. M.; Englot, D. J.; Constantinidis, C.; Roberson, S. W.; Claassen, D. O.; Bick, S. K.
10.1101/2024.07.02.601451 — neuroscience — Posted on 2024-07-04
4380 LEAFY and WAPO1 jointly regulate spikelet number per spike and floret development in wheat
Paraiso, F.; Lin, H.; Li, C.; Woods, D. P.; Lan, T.; Burguener, G. F.; Tumelty, C.; Debernardi, J. M.; Joe, A.; Dubcovsky, J.
10.1101/2023.11.02.565263 — plant biology — Posted on 2024-07-04
4381 StarSignDNA: Signature tracing for accurate representation of mutational processes
Bope, c. D.; Kalyanasundaram, S.; Rand, K. D.; Nakken, S.; Lingjaerde, O. C.; Hovig, E.
10.1101/2024.06.29.601345 — bioinformatics — Posted on 2024-07-04
4382 Increased female competition for males with enhanced foraging skills in Guinea baboons
O'Hearn, W. J.; Beckmann, J.; von Fersen, L.; Dal Pesco, F.; Mundry, R.; Keupp, S.; Diakhate, N.; Niederbremer, C.; Fischer, J.
10.1101/2024.07.04.602040 — animal behavior and cognition — Posted on 2024-07-04
4383 Genetic association data are broadly consistent with stabilizing selection shaping human common diseases and traits
Koch, E. M.; Connally, N. J.; Baya, N. A.; Reeve, M. P.; Daly, M. J.; Neale, B. M.; Lander, E. S.; Bloemendal, A.; Sunyaev, S. R.
10.1101/2024.06.19.599789 — genomics — Posted on 2024-07-04
4384 De novo acquisition of antibiotic resistance in six species of bacteria
Wang, X. H.; de Koster, A. H.; Koenders-van Sintanneland, B. B.; Jonker, M. J.; Brul, S.; ter Kuile, B. H.
10.1101/2024.07.03.601945 — microbiology — Posted on 2024-07-04
4386 The Staphylococcus aureus small non-coding RNA IsrR regulates TCA cycle activity and virulence
Rios, G.; McReynolds, A. K. G.; Pagella, E. A.; Norambuena, J.; Briaud, P.; Zheng, V.; Munneke, M. J.; Kim, J.; Racine, H.; Carroll, R. K.; Zelzion, E.; Skaar, E. P.; Bose, J. L.; Parker, D.; Lalaouna, D.; Boyd, J. M.
10.1101/2024.07.03.601953 — microbiology — Posted on 2024-07-04
4388 Development of a highly active engineered PETase enzyme for polyester degradation
Bhattacharya, S.; Castagna, R.; Estiri, H.; Upmanis, T.; Ricci, A.; Gautieri, A.; Parisini, E.
10.1101/2024.07.04.602061 — bioengineering — Posted on 2024-07-04
4389 Conserved loop of a phase modifier endows protein condensates with fluidity
Kawamukai, H.; Matsusaki, M.; Tanimoto, T.; Watabe, M.; Morishima, K.; Tomita, S.; Shinkai, Y.; Niwa, T.; Mannen, T.; Kumeta, H.; Nanaura, H.; Kato, K.; Mabuchi, T.; Aiba, Y.; Uehara, T.; Isozumi, N.; Hara, Y.; Kanemura, S.; Matsumura, H.; Sugie, K.; Ishimori, K.; Muraoka, T.; Sugiyama, M.; Okumura, M.; Mori, E.; Yoshizawa, T.; Saio, T.
10.1101/2024.07.03.601791 — biochemistry — Posted on 2024-07-04
4392 Female oviposition decisions are influenced by the microbial environment
Fowler, E. K.; Friend, L. A.; Churchill, E. R.; Yu, D. W.; Archetti, M.; Bourke, A. F. G.; Bretman, A.; Chapman, T.
10.1101/2024.07.03.601843 — evolutionary biology — Posted on 2024-07-04
4393 What determines the vertical structuring of pelagic ecosystems in the global ocean?
Belharet, M.; Lengaigne, M.; Barrier, N.; Brierley, A. S.; Irigoien, X.; Proud, R.; Maury, O.
10.1101/2024.07.04.602098 — ecology — Posted on 2024-07-04
4395 Dynamic Plk1 recruitment to the inner centromere
Norman, R. X.; Lera, R. F.; Mattix, A. A.; Shen, Z.; Carlsen, C. L.; Burkard, M. E.
10.1101/2024.07.03.601947 — cell biology — Posted on 2024-07-04
4397 Activated RNAi does not rescue piRNA pathway deficiency in testes
Taborska, E.; Loubalova, Z.; Kulmann, M. I. R.; Malik, R.; Buccheri, V.; Pasulka, J.; Horvat, F.; Jenickova, I.; Sedlacek, R.; Svoboda, P.
10.1101/2024.07.04.602103 — molecular biology — Posted on 2024-07-04
4398 An emerging PB2-627 polymorphism increases the pandemic potential of avian influenza virus by breaking through ANP32 host restriction in mammalian and avian hosts
Guo, Y.; Shu, S.; Zhou, Y.; Peng, W.; Jiang, Z.; Li, Y.; Li, T.; Du, F.; Wang, L.; Chen, X.; Dong, J.; Zhao, C.; Wang, M. H.; Sun, Y.; Sun, H.; Lu, L.; Digard, P.; Chang, K.-c.; Yen, H.-L.; Liu, J.; Pu, J.
10.1101/2024.07.03.601996 — microbiology — Posted on 2024-07-04
4399 Alpine lakes harbor diverse, endemic and structurally unique RNA viruses
Wu, L.; Liu, Y.; Shi, W.; Chang, T.; Liu, P.; Liu, K.; He, Y.; Li, Z.; Shi, M.; Jiao, N.; Dong, X.; Zheng, Q.
10.1101/2024.07.04.601995 — microbiology — Posted on 2024-07-04
4400 Oxygen metabolism in descendants of the archaeal-eukaryotic ancestor
Appler, K. E.; Lingford, J. P.; Gong, X.; Panagiotou, K.; Leao, P.; Langwig, M.; Greening, C.; Ettema, T. J. G.; De Anda, V.; Baker, B. J.
10.1101/2024.07.04.601786 — microbiology — Posted on 2024-07-04
4402 Sensitive detection of synthetic response to cancer immunotherapy driven by gene paralog pairs
Dong, C.; Zhang, F.; He, E.; Ren, P.; Verma, N.; Zhu, X.; Feng, D.; Zhao, H.; Chen, S.
10.1101/2024.07.02.601809 — bioinformatics — Posted on 2024-07-04
4403 G-quadruplex formation in long non-coding RNAs dysregulated in colorectal cancer
Sharma, S.; Shukla, C.; Mitteaux, J.; Pipier, A.; Pirrotta, M.; Penouilh, M.-J.; Monchaud, D.; Datta, B.
10.1101/2024.07.04.602106 — biochemistry — Posted on 2024-07-04
4405 Self-Organization of Sinusoidal Vessels in Pluripotent Stem Cell-derived Human Liver Bud Organoids
Saiki, N.; Nio, Y.; Yoneyama, Y.; Kawamura, S.; Iwasawa, K.; Kawakami, E.; Araki, K.; Fukumura, J.; Sakairi, T.; Ohmura, R.; Koido, M.; Funata, M.; Thompson, W. L.; Cruz-Encarnacion, P.; Chen, Y.-W.; Takebe, T.
10.1101/2024.07.02.601804 — developmental biology — Posted on 2024-07-04
4406 Constant surface area-to-volume ratio during cell growth as a design principle in mammalian cells
Wu, W.; Lam, A. R.; Suarez, K.; Smith, G. N.; Duquette, S. M.; Yu, J.; Mankus, D.; Bisher, M.; Lytton-Jean, A.; Manalis, S. R.; Miettinen, T. P.
10.1101/2024.07.02.601447 — cell biology — Posted on 2024-07-04
4407 IL-13 decreases susceptibility to airway epithelial SARS-CoV-2 infection but increases disease severity in vivo
Ghimire, S.; Xue, B.; Li, K.; Gannon, R. M.; Wohlford-Lenane, C. L.; Thurman, A. L.; Gong, H.; Necker, G. C.; Zheng, J.; Meyerholz, D. K.; Perlman, S.; McCray, P. B.; Pezzulo, A. A.
10.1101/2024.07.03.601941 — cell biology — Posted on 2024-07-04
4408 Ixodes ricinus bites promote allergic skin inflammation and intestinal tuft and mast cell expansion in mice.
Leyva-Castillo, J. M.; Strakosha, M.; Smith, S. E. M.; Vega-Mendoza, D.; Elkins, M.; Chou, J.; Vogel, P.; Boulanger, N.
10.1101/2024.07.02.600632 — immunology — Posted on 2024-07-04
4411 Cryo-EM of AKAP350 reveals fibrillar clusters and a potential association with DNA
Dai, D. L.; Keszei, A. F. A.; kolobova, e.; St-Germain, J.; Hasan, S. M. N.; Liu, A. C. H.; Zhang, X.; Raught, B.; Goldenring, J. R.; Mazhab-Jafari, M. T.
10.1101/2024.07.02.601773 — biochemistry — Posted on 2024-07-04
4412 Complement C5a receptor 1 blockade reverses cognitive deficits following cranialradiation therapy for brain cancer
Krattli, R. P.; Do, A. H.; El-Khatib, S. M.; Alikhani, L.; Markarian, M.; Vagadia, A. R.; Usmani, M. T.; Madan, S.; Baulch, J. E.; Clark, R. J.; Woodruff, T. M.; Tenner, A. J.; Acharya, M. M.
10.1101/2024.07.02.601806 — neuroscience — Posted on 2024-07-04
4414 Spatial gene expression at single-cell resolution from histology using deep learning with GHIST
Fu, X.; Cao, Y.; Bian, B.; Wang, C.; Graham, D.; Pathmanathan, N.; Patrick, E.; Kim, J.; Yang, J. Y. H.
10.1101/2024.07.02.601790 — bioinformatics — Posted on 2024-07-04
4416 Compressive Pangenomics Using Mutation-Annotated Networks
Walia, S.; Motwani, H.; Smith, K.; Corbett-Detig, R.; Turakhia, Y.
10.1101/2024.07.02.601807 — bioinformatics — Posted on 2024-07-04
4417 Transcriptional landscape of a hypoxia response identifies cell-specific pathways for adaptation
Kong, J. N.; Ghosh, D. D.; Savvidis, A.; Sando, S. R.; Droste, R.; Horvitz, H. R.
10.1101/2024.07.02.601765 — genetics — Posted on 2024-07-04
4419 Substrate Rigidity Modulates Segmentation Clock Dynamics in Isolated Presomitic Mesoderm Cells
Sung, C.-Y.; Kadiyala, U.; Blanchard, O.; Yourston, L.; Walker, D.; Li, L.; Fu, J.; Yang, Q.
10.1101/2024.07.02.601712 — developmental biology — Posted on 2024-07-04
4421 Disruption of the PGE2 synthesis / response pathway restrains atherogenesis in programmed cell death-1 (Pd-1) deficient hyperlipidemic mice
Ricciotti, E.; Tang, S. Y.; Mrcela, A.; Das, U.; Lordan, R.; Joshi, R.; Ghosh, S.; Aoyama, J.; McConnell, R.; Yang, J.; Grant, G. R.; FitzGerald, G. A.
10.1101/2024.07.02.601762 — pharmacology and toxicology — Posted on 2024-07-04
4422 Memantine Inhibits Calcium-Permeable AMPA Receptors
Carrillo, E.; Montano Romero, A.; Gonzalez, C. U.; Turcu, A. L.; Chen, S.-R.; Chen, H.; Pan, H.-L.; Vazquez, S.; Twomey, E. C.; Jayaraman, V.
10.1101/2024.07.02.601784 — biophysics — Posted on 2024-07-04
4423 Biomolecular condensates are characterized by interphase electric potentials
Posey, A. E.; Bremer, A.; Erkamp, N. A.; Pant, A.; Knowles, T.; Dai, Y.; Mittag, T.; Pappu, R. V.
10.1101/2024.07.02.601783 — biophysics — Posted on 2024-07-04
4425 Molecular characterization of response to etrolizumab and anti-TNF reveals treatment resistance in ulcerative colitis is associated with the abundance of residual neutrophil subsets and inflammatory fibroblast populations
Toghi Eshghi, S.; Gubatan, J. M.; Mazrooei, P.; Quintanilla, L.; Nguyen, A.; Au-Yeung, A.; Holman, D. R.; Takahashi, C.; Schiffman, C.; O'Gorman, W.; Keir, M.; Ramanujan, S.; Rogalla, S.; Hackney, J.; McBride, J. M.
10.1101/2024.07.02.601267 — immunology — Posted on 2024-07-04
4426 TDP43 autoregulation gives rise to shortened isoforms that are tightly controlled by both transcriptional and post-translational mechanisms
Dykstra, M. M.; Weskamp, K.; Gomez, N. B.; Waksmacki, J.; Tank, E. M.; Glineburg, M. R.; Snyder, A.; Pinarbasi, E.; Bekier, M.; Li, X.; Bai, J.; Shahzad, S.; Nedumaran, J.; Wieland, C.; Stewart, C.; Willey, S.; Grotewold, N.; McBride, J.; Moran, J.; Suryakumar, A.; Lucas, M.; Tessier, P.; Ward, M.; Todd, P.; Barmada, S.
10.1101/2024.07.02.601776 — neuroscience — Posted on 2024-07-04
4428 Microglia mediate the early-life programming of adult glucose control
Valdearcos, M.; McGrath, E. R.; Brown Mayfield, S.; Folick, A.; Cheang, R. T.; Li, L.; Bachor, T. P.; Lippert, R. N.; Xu, A. W.; Koliwad, S. K.
10.1101/2024.07.02.601752 — physiology — Posted on 2024-07-04
4430 Preclinical evaluation of pharmacological inhibition of SIRT1 on the growth of tumoral and metastatic granulosa cells
Cluzet, V.; Airaud, E.; Devillers, M. M.; Petit, F.; Leary, A.; Pierre, A.; Li, H.; Day, C.-P.; Weyemi, U.; Chauvin, S.; Guigon, C.
10.1101/2024.07.02.601506 — cancer biology — Posted on 2024-07-04
4431 Impact of PI3K pathway alterations on response to immune checkpoint inhibitors in HPV-negative head and neck squamous cell carcinoma
Park, J. C.; Basak, N. P.; Useche, M.; Park, J. S.; Mandakulutur, S. G.; Prabha, A.; Chandra Reddy, J.; Varvares, M.; Wirth, L.; Faquin, W.; Sankaran, S.; Saladi, S. V.
10.1101/2024.07.02.601738 — cancer biology — Posted on 2024-07-04
4433 Metagenomic peek into a corn mummy
Solymosi, N.; Pap, B.; Nagy, S. A.; Toth, A. G.; Kevely, F. J.; Maroti, G.; Csabai, I.; Kothay, K.; Magyar, D.
10.1101/2024.07.02.601727 — bioinformatics — Posted on 2024-07-04
4436 Metabolic Profiles of Encapsulated Chondrocytes Exposed to Short-Term Simulated Microgravity
Bergstrom, A. R.; Glmm, M. G.; Houske, E. A.; Cooper, G.; Viles, E.; Bourekis, K.; Welhaven, H. D.; Brahmachary, P. P.; Hahn, A. K.; June, R. K.
10.1101/2024.07.01.601604 — bioengineering — Posted on 2024-07-04
4437 Opto-Myomatrix: μLED integrated microelectrode arrays for optogenetic activation and electrical recording in muscle tissue
Lu, J.; Zia, M.; Baig, D. A.; Yan, G.; Kim, J. J.; Nagapudi, K.; Anschutz, P.; Oh, S.; O'Connor, D. H.; Sober, S. J.; Bakir, M. S.
10.1101/2024.07.01.601601 — bioengineering — Posted on 2024-07-04
4440 Genomic Signatures of Domestication in a Fungus Obligately Farmed by Leafcutter Ants
Leal-Dutra, C. A.; Vizueta, J.; Baril, T.; Kooij, P. W.; Rodsgaard-Jorgensen, A.; Schantz-Conlon, B. H.; Shik, J. Z.
10.1101/2024.07.02.601708 — evolutionary biology — Posted on 2024-07-04
4441 Salinisation and warming disrupt predator-induced drift behaviour in aquatic predator-prey interactions
Vermiert, A.-M.; Madge Pimentel, I.; Rehsen, P. M.; Otto, T.; Horstmann, M.; Beermann, A. J.; Leese, F.; Weiss, L. C.; Tollrian, R.
10.1101/2024.07.02.601583 — ecology — Posted on 2024-07-04
4446 Epigenetic changes regulating the epithelial-mesenchymal transition in human trophoblast differentiation
Ackerman, W. E.; Rigo, M. M.; DaSilva-Arnold, S. C.; Do, C.; Tariq, M.; Salas, M.; Castano, A.; Zamudio, S.; Tycko, B.; Illsley, N. P.
10.1101/2024.07.02.601748 — developmental biology — Posted on 2024-07-04
4448 Lack of Synergistic Outcomes with Roflumilast Combined with Levetiracetam or Adipose Stem Cell Secretome After Spinal Cord Injury
Sousa, C.; lima, R.; Gomes, E. D.; Silva, D.; Cibrao, J.; Pinho, T.; Santos, D.; Afonso, J.; Martins-Macedo, J.; Monteiro, A.; Salgado, A. J.; Silva, N. A.
10.1101/2024.07.02.601664 — neuroscience — Posted on 2024-07-04
4449 Reciprocal interactions between CA1 pyramidal and axo-axonic cells control sharp wave-ripple events
Gilbert, E. T.; Klaver, L. M. F.; Arndt, K. C.; Kim, J.; Jia, X.; McKenzie, S.; English, D. F.
10.1101/2024.07.02.601726 — neuroscience — Posted on 2024-07-04
4451 Redox signaling by hydrogen peroxide modulates axonal microtubule organization and induces a specific phosphorylation signature of microtubule proteins distinct from distress
Conze, C.; Trushina, N. I.; Monteiro-Abreu, N.; Villar Romero, D.; Wienbeuker, E.; Schwarze, A.-S.; Holtmannspoetter, M.; Bakota, L.; Brandt, R.
10.1101/2024.07.01.601594 — neuroscience — Posted on 2024-07-04
4452 EPILEPTOGENESIS INHIBITS THE CIRCADIAN CLOCK AND RESHAPES THE DIURNAL TRANSCRIPTOMIC RHYTHMICITY IN THE MOUSE HIPPOCAMPUS
Benvenutti, R.; Bruno, D. C. F.; Gallas-Lopes, M.; Veno, M. T.; Bruxel, E. M.; Strickland, T.; Ramsook, A.; Wadgaonkar, A.; Jiang, Y.; Sanz-Rodriguez, A.; Sinkkonen, L.; Alvim, M. K. M.; Yasuda, C. L.; Rogerio, F.; Cendes, F.; Henshall, D. C.; Curtis, A. M.; Kobow, K.; Lopes-Cendes, I.; Reschke, C. R.
10.1101/2024.07.02.601732 — neuroscience — Posted on 2024-07-04
4453 Spectrotemporal profiling of ultrasonic vocalizations during neonatal opioid withdrawal reveals a kappa opioid receptor component in female mice
Wingfield, K. K.; Misic, T.; Jain, K.; McDermott, C. S.; Abney, N. M.; Richardson, K. T.; Rubman, M. B.; Beierle, J. A.; Miracle, S. A.; Sandago, E. J.; Baskin, B. M.; Borrelli, K. N.; Yao, E. J.; Wachman, E. M.; Bryant, C. D.
10.1101/2024.07.02.601766 — neuroscience — Posted on 2024-07-04
4455 Parallel measurement of transcriptomes and proteomes from same single cells using nanodroplet splitting
Fulcher, J. M.; Markillie, L. M.; Mitchell, H. D.; Williams, S. M.; Engbrecht, K. M.; Degnan, D. J.; Bramer, L.; Moore, R. J.; Chrisler, W. B.; Cantlon-Bruce, J.; Bagnoli, J. W.; Qian, W.; Seth, A.; Pasa-Tolic, L.; Zhu, Y.
10.1101/2022.05.17.492137 — systems biology — Posted on 2024-07-04
4457 Tks5 interactome reveals ER-associated machinery translation in invadosomes.
NORMAND, L.; BONNARD, B.; Sala, M.; DI-TOMMASO, S.; DOURTHE, C.; RAYMOND, A.-A.; DUPUY, J.-W.; MERCIER, L.; GOETZ, J. G.; MOREAU, V.; HENRIET, E.; SALTEL, F.
10.1101/2024.07.02.601728 — cancer biology — Posted on 2024-07-04
4458 Uridine Phosphorylase-1 supports metastasis of mammary cancer by altering immune and extracellular matrix landscapes of the lung
Whyte, D.; Vande Voorde, J.; Sumpton, D.; Dhayade, S.; Dornier, E.; Moore, M.; Novo, D.; Peters, J.; Wiesheu, R.; Mackey, J. B.; McFarlane, A. J.; Fercoq, F.; Fisher, S.; Dehesa Caballero, C.; Gilroy, K.; Redmond, K. L.; Mitchell, L. E.; Anderson, E.; Thomson, G.; Dzierozynski, L. N.; Apiz Saab, J. J.; Lewis, C. A.; Muir, A.; Halbrook, C. J.; Strathdee, D.; Jackstadt, R.; Nixon, C.; Dunne, P.; Steele, C. W.; Carlin, L. M.; Macpherson, I. R.; Roberts, E. W.; Coffelt, S. B.; Blyth, K.; Sansom, O. J.; Norman, J. C.; Clarke, C. J.
10.1101/2024.07.02.601676 — cancer biology — Posted on 2024-07-04
4459 An integrin centered complex coordinates ion transport and pH to regulate f-actin organization and cell migration in breast cancer.
Capitani, C.; Iorio, J.; Lastraioli, E.; Duranti, C.; Bagni, G.; Chioccioli Altadonna, G.; Colasurdo, R.; Scarpellino, G.; Fraser, S. P.; Becchetti, A.; Djamgoz, M. B. A.; Arcangeli, A.
10.1101/2024.07.02.601509 — cancer biology — Posted on 2024-07-04
4461 Chaotropic Agent-assisted Supported Lipid Bilayer Formation
Cawley, J. L.; Santa, D. E.; Singh, A. N.; Odudimu, A. T.; Berger, B. A.; Wittenberg, N. J.
10.1101/2024.07.02.601713 — biophysics — Posted on 2024-07-04
4463 tauX: A Gene Expression Ratio Strategy to Improve Machine Learning Applications in Precision Medicine
Pfeil, J.; Ma, L.; Lo, H. C.; Turan, T.; McLaughlin, R. T.; Shi, X.; Villarruel, S.; Wilson, S.; Zhao, X.; Samayoa, J.; Halliwill, K.
10.1101/2024.07.01.601595 — bioinformatics — Posted on 2024-07-04
4469 Reproductive output of old polygynous males is limited by seminal fluid, not sperm number
Sanghvi, K.; Shandilya, S.; Brown, A.; Todorova, B.; Jahn, M.; Gascoigne, S.; Camilleri, T.-L.; Pizzari, T.; Sepil, I.
10.1101/2024.07.02.601670 — evolutionary biology — Posted on 2024-07-04
4470 Ecology not genetics explains correlated trait divergence during speciation
de Carvalho, C.; Planidin, N.; Villoutreix, R.; Soria-Carrasco, V.; Riesch, R.; Feder, J.; Parchman, T.; Slate, J.; Gompert, Z.; Nosil, P.
10.1101/2024.07.02.601691 — evolutionary biology — Posted on 2024-07-04
4472 Innovative Use of Depth Data to Estimate Energy Intake and Expenditure in Adelie Penguins
Dupuis, B.; Kato, A.; Hicks, O.; Wisniewska, D. M.; Marciau, C.; Angelier, F.; Ropert-Coudert, Y.; Chimienti, M.
10.1101/2024.07.02.601650 — ecology — Posted on 2024-07-04
4473 A genome engineered tool set for Drosophila TGF-β/BMP signaling studies
Ell, C.-M.; Safyan, A.; Chayengia, M.; Kustermann, M. M. M.; Lorenz, J.; Schächtle, M.; Pyrowolakis, G.
10.1101/2024.07.02.601693 — developmental biology — Posted on 2024-07-04
4474 The CCT chaperonin and actin modulate the ER and RNA-binding protein condensation during oogenesis to maintain translational repression of maternal mRNA and oocyte quality
Elaswad, M. T.; Gao, M.; Tice, V. E.; Bright, C. G.; Thomas, G. M.; Munderloh, C.; Trombley, N. J.; Haddad, C. N.; Johnson, U. G.; Cichon, A. N.; Schisa, J. A.
10.1101/2024.07.01.601596 — developmental biology — Posted on 2024-07-04
4476 Basophils drive the resolution and promote wound healing in adult and aged mice
Bex, J.; Peter, V.; Saji, C.; Chapart, L.; Jin, S.; Gauthier, G.; Thibaudeau, O.; Thaminy, M. K.; Tchen, J.; Simon, Q.; Dai, X.; Miyake, K.; Karasuyama, H.; Jiang, J. X.; Naidoo, K.; Benhamou, M.; Blank, U.; Monteiro, R.; Le Gros, G.; Charles, N.; Pellefigues, C.
10.1101/2024.07.02.601665 — immunology — Posted on 2024-07-04
4478 Poly(allylamine)-tripolyphosphate polymeric nanoparticle as an NLRP3-dependent systemic adjuvant for the vaccine development
Rizzo, G. P.; Sanches, R. C.; Chavero, C.; Bianchi, D. S.; Apuzzo, E.; Herrera, S. E.; Agazzi, M. L.; Keitelman, I. A.; Trevani, A. S.; Oliveira, S. C.; Azzaroni, O.; Smaldini, P. L.; Docena, G. H.
10.1101/2024.07.01.601578 — immunology — Posted on 2024-07-04
4480 Dynamic functional connectivity correlates of trait mindfulness in early adolescence
Treves, I. N.; Marusak, H. A.; Decker, A.; Kucyi, A.; Hubbard, N. A.; Bauer, C. C. C.; Leonard, J.; Grotzinger, H.; Giebler, M. A.; Camacho Torres, Y.; Imhof, A.; Romeo, R.; Calhoun, V.; Gabrieli, J. D. E.
10.1101/2024.07.01.601544 — neuroscience — Posted on 2024-07-04
4483 iTome Volumetric Serial Sectioning Apparatus for TEM
Peale, D. R.; Hess, H.; Lee, P. R.; Cardona, A.; Bock, D.; Schneider-Mizell, C. M.; Fetter, R. D.; Lee, W.-P.; Robinson, C. G.; Iyer, N.; Managan, C.
10.1101/2024.07.02.601671 — neuroscience — Posted on 2024-07-04
4484 Microglia-astrocyte interplay mitigates Aβ toxicity in a novel human 3D neurosphere model of Alzheimer's Disease
Wendt, S.; Lin, A. J.; Ebert, S. N.; Brennan, D. J.; Cai, W.; Bai, Y.; Sorrentino, S.; Groten, C. J.; Lee, C.; Frew, J.; Choi, H. B.; Karamboulas, K.; Delhaye, M.; Kaplan, D. R.; Miller, F.; MacVicar, B. A.; Nygaard, H. B.
10.1101/2024.07.01.601570 — neuroscience — Posted on 2024-07-04
4493 Leveraging machine learning to streamline the development of liposomal drug delivery systems
Eugster, R.; Orsi, M.; Buttitta, G.; Serafini, N.; Tiboni, M.; Casettari, L.; Reymond, J.-L.; Aleandri, S.; Luciani, P.
10.1101/2024.07.01.600773 — pharmacology and toxicology — Posted on 2024-07-04
4495 The metabolic benefits of thermogenic stimulation are preserved in aging
Natarajan, D.; Plakkot, B.; Tiwari, K.; Ekambaram, S.; Wang, W.; Rudolph, M.; Mohammad, M.; Chacko, S.; Subramanian, M.; Tarantini, S.; Yabluchanskiy, A.; Ungvari, Z.; Csiszar, A.; Balasubramanian, P.
10.1101/2024.07.01.601572 — pharmacology and toxicology — Posted on 2024-07-04
4496 Tumor- and immune-derived N-acetyl-β-D-hexosaminidase drive colorectal cancer and stratify patient risk
Kawahara, R.; Kautto, L.; Bansal, N.; Dipta, P.; Chau, T. H.; Liquet-Weiland, B.; Ahn, S. B.; Thaysen-Andersen, M.
10.1101/2024.07.02.601644 — cancer biology — Posted on 2024-07-04
4497 Structure of a novel α-synuclein filament fold from multiple system atrophy
Yan, N. L.; Candido, F.; Tse, E.; Melo, A. A.; Prusiner, S. B.; Mordes, D. A.; Southworth, D. R.; Paras, N. A.; Merz, G. E.
10.1101/2024.07.01.601365 — biophysics — Posted on 2024-07-04
4499 Replacing non-biomedical concepts improves embedding of biomedical concepts
Niyonkuru, E.; Soto Gomez, M.; Casiraghi, E.; Antogiovanni, S.; Blau, H.; Reese, J. T.; Valentini, G.; Robinson, P. N.
10.1101/2024.07.01.601556 — bioinformatics — Posted on 2024-07-04
4502 Disease exacerbation in MYOrganoids derived from Duchenne Muscular Dystrophy iPSC reveals limitations of microdystrophin therapeutic efficacy
Palmieri, L.; Pili, L.; Jaber, A.; Vu Hong, A.; Moula, M.; El Khoury, R.; Brochiet, G.; Bigot, A.; Israeli, D.; Richard, I.; Albini, S.
10.1101/2023.07.26.550063 — bioengineering — Posted on 2024-07-04
4504 Transposable element expression with variation in sex chromosome number: insights into a toxic Y effect on human longevity
Teoli, J.; Merenciano, M.; Fablet, M.; Necsulea, A.; Siqueira-de-Oliveira, D.; Brandulas-Cammarata, A.; Labalme, A.; Lejeune, H.; Lemaitre, J.-F.; Gueyffier, F.; Sanlaville, D.; Bardel, C.; Vieira, C.; Marais, G. A.; Plotton, I.
10.1101/2023.08.03.550779 — genomics — Posted on 2024-07-04
4506 Chitosan reduces naturally occurring plant pathogenic fungi and increases nematophagous fungus Purpureocillium in field soil
Lopez-Nunez, R.; Prieto-Rubio, J.; Bautista-Carrascosa, I.; Lidon-Cerezuela, A. L.; Lopez-Moya, F.; Lopez-Llorca, L. V.
10.1101/2024.07.01.600678 — ecology — Posted on 2024-07-04
4512 Immune Checkpoint Inhibition-related Neuroinflammation Disrupts Cognitive Function
Ifejeokwu, O. V.; Do, A. H.; El-Khatib, S. M.; Ho, N. H.; Zavala, A.; Othy, S.; Acharya, M. M.
10.1101/2024.07.01.601087 — neuroscience — Posted on 2024-07-04
4513 Human birth tissue products as a non-opioid medicine to inhibit post-surgical pain
Zhang, C.; Huang, Q.; Ford, N. C.; Limjunyawong, N.; Lin, Q.; Yang, F.; Cui, X.; Uniyal, A.; Liu, J.; Mahabole, M.; He, H.; Wang, X.; Duff, I.; Wang, Y.; Wan, J.; Zhu, G.; Raja, S. N.; Jia, H.; Yang, D.; Dong, X.; Cao, X.; Tseng, S.; He, S.; Guan, Y.
10.1101/2024.05.19.594874 — neuroscience — Posted on 2024-07-04
4514 The relationship between microbial community succession, decay, and anatomical character loss in non-biomineralised animals
Clements, T.; Goodall, R.; Gabbott, S.; Murdock, D.; Clokie, M.; Millard, A.; Turkington, C.; Bath-Enright, O.; Purnell, M. A.
10.1101/2024.07.01.601543 — paleontology — Posted on 2024-07-04
4516 High-speed 3D DNA PAINT and unsupervised clustering for unlocking 3D DNA origami cryptography
Wisna, G. B. M.; Sukhareva, D.; Zhao, J.; Satyabola, D.; Matthies, M.; Roy, S.; Wang, C.; Sulc, P.; Yan, H.; Hariadi, R. F.
10.1101/2023.08.29.555281 — biophysics — Posted on 2024-07-04
4517 The Asgard archaeal ESCRT-III system forms helical filaments and remodels eukaryotic membranes, shedding light on the emergence of eukaryogenesis
Melnikov, N.; Junglas, B.; Halbi, G.; Nachmias, D.; Zerbib, E.; Upcher, A.; Zalk, R.; Sachse, C.; Bernheim, A.; Elia, N.
10.1101/2022.09.07.506706 — biochemistry — Posted on 2024-07-04
4518 T7 DNA polymerase treatment improves quantitative sequencing of both double-stranded and single-stranded DNA viruses
Billaud, M.; Theodorou, I.; Lamy-Besnier, Q.; Shah, S. A.; Lecointe, F.; De Sordi, L.; De Paepe, M.; Petit, M.-A.
10.1101/2022.12.12.520144 — genomics — Posted on 2024-07-04
4520 Deep sequencing of 16 Ixodes ricinus ticks unveils insights into their interactions with endosymbionts
Lesiczka, P. M.; Azagi, T.; Krawczyk, A. I.; Scott, W. T.; Dirks, R. P.; Simo, L.; Dobler, G.; Nijsse, B.; Schaap, P. J.; Sprong, H.; Koehorst, J. J.
10.1101/2024.04.22.590557 — microbiology — Posted on 2024-07-04
4521 Phageome transfer from gut to circulation and its regulation by human immunity
Szymczak, A.; Gembara, K.; Ferenc, S.; Majewska, J.; Miernikiewicz, P.; Harhala, M.; Rybicka, I.; Strapagiel, D.; Slomka, M.; Lach, J.; Gnus, J.; Staczek, P.; Witkiewicz, W.; Dabrowska, K.
10.1101/2024.06.05.597592 — microbiology — Posted on 2024-07-04
4523 Metabolic Dependency Shapes Bivalent Antiviral Response in Host Cells in response to poly:IC: The Role of Glutamine
Lebeau, G.; Paulo-Ramos, A.; Hoareau, M.; El Safadi, D.; Meilhac, O.; Krejbich-Trotot, P.; Roche, M.; Viranaicken, W.
10.1101/2023.08.31.555729 — immunology — Posted on 2024-07-04
4524 Comparative neuroimaging of the carnivoran brain: Neocortical sulcal anatomy
Boch, M.; Karadachka, K.; Loh, K. K.; Benn, R. A.; Roumazeilles, L.; Bertelsen, M. F.; Manger, P. R.; Wriggelsworth, E.; Spiro, S.; Spocter, M. A.; Johnson, P. J.; Avelino-de-Souza, K.; Patzke, N.; Lamm, C.; Miller, K. L.; Sallet, J.; Khrapitchev, A. A.; Tendler, B. C.; Mars, R. B.
10.1101/2024.06.03.597118 — neuroscience — Posted on 2024-07-04
4527 Control of innate olfactory valence by segregated cortical amygdala circuits
Howe, J. R.; Chan, C.-L.; Lee, D.; Blanquart, M.; Romero, H.; Zadina, A. N.; Lemieux, M. E.; Desplats, P. A.; Tye, K. M.; Root, C. M.
10.1101/2024.06.26.600895 — neuroscience — Posted on 2024-07-04
4529 Antibody-based immunotherapy targeting FAM19A5 reverses synaptic loss and improves cognitive function in Alzheimer's disease.
Seong, J. Y.; Kim, H.-B.; Yoo, S.; Kwak, H.; Ma, S.-X.; Kim, R.; Lee, M.; Ha, N.; Pyo, S.; Kwon, S.-G.; Cho, E.-H.; Lee, S.-M.; Jang, J.; Kim, W.; Park, H.-C.; Baek, M.; Park, Y.; Park, J.-Y.; Park, J.-W.; Hwang, S. W.; Hwang, J.-I.
10.1101/2023.11.22.568357 — neuroscience — Posted on 2024-07-04
4530 Trazodone, dibenzoylmethane and tauroursodeoxycholic acid do not prevent motor dysfunction and neurodegeneration in Marinesco-Sjögren syndrome mice
Lavigna, G.; Grasso, A.; Pasini, C.; Grande, V.; Mignogna, L.; Restelli, E.; Masone, A.; Fracasso, C.; Lucchetti, J.; Gobbi, M.; Chiesa, R.
10.1101/2024.04.30.591862 — pharmacology and toxicology — Posted on 2024-07-04
4531 Linker histone H1-0 is a specific mediator of the repressive ETV6::RUNX1 transcriptional landscape
Jepsen, V. H.; Hanel, A.; Picard, D.; Mehtonen, J.; Hasselmann, R.; Schliehe-Diecks, J.; Scharov, K.; Tu, J.-W.; Bhave, R.; Kameri, E.; Qin, N.; Wang, H.; Zhuang, Z.; Wagener, R.; Blümel, L.; Lautwein, T.; Hein, D.; Kögler, G.; Remke, M.; Bhatia, S.; Heinäniemi, M.; Borkhardt, A.; Fischer, U.
10.1101/2024.06.28.601221 — cancer biology — Posted on 2024-07-04
4532 Structural visualisation of the dynamics of DNA unwinding by a replicative helicase
Shahid, T.; Tehseen, M.; Alhudhali, L.; Clark, A. R.; Savva, C. G.; Hamdan, S. M.; De Biasio, A.
10.1101/2024.04.19.590217 — biophysics — Posted on 2024-07-04
4535 Castanet: a pipeline for rapid analysis of targeted multi-pathogen genomic data
Mayne, R. M.; Secret, S.; Geoghegan, C.; Trebes, A.; Kean, K.; Reid, K.; Lin, G.-L.; Ansari, M. A.; de Cesare, M.; Bonsall, D.; Elliott, I.; Piazza, P.; Brown, A.; Bray, J.; Knight, J. C.; Harvala, H.; Breuer, J.; Simmonds, P.; Bowden, R. J.; Golubchik, T.
10.1101/2024.06.28.601013 — bioinformatics — Posted on 2024-07-04
4537 Zinc stimulation of phytoplankton in a low carbon dioxide, coastal Antarctic environment
Kell, R. M.; Subhas, A. V.; Schanke, N. L.; Lees, L. E.; Chmiel, R. J.; Rao, D.; Brisbin, M. M. M.; Moran, D. M.; McIlvin, M. R.; Bolinesi, F.; Mangoni, O.; Casotti, R.; Balestra, C.; Horner, T.; Dunbar, R. B.; Allen, A. E.; DiTullio, G. R.; Saito, M. A.
10.1101/2023.11.05.565706 — biochemistry — Posted on 2024-07-04
4542 Gossamer: Scaling Image Processing and Reconstruction to Whole Brains
Marrett, K.; Moradi, K.; Park, C. S.; Yan, M.; Choi, C.; Zhu, M.; Akram, M.; Nanda, S.; Xue, Q.; Mun, H.-S.; Gutierrez, A. E.; Rudd, M.; Zingg, B.; Magat, G.; Wijaya, K.; Dong, H.; Yang, X. W.; Cong, J.
10.1101/2024.04.07.588466 — neuroscience — Posted on 2024-07-04
4543 Identification and validation of reference genes for RT-qPCR single-gene relative expression analysis in Taenia solium pre-adult stages
Castaneda, D.; Maravi, J. d. C.; Gutierrez-Loli, R.; Villar, V.; Blume La Torre, J.; Del Aguila, S. W.; Guerra-Giraldez, C.
10.1101/2022.03.22.485324 — microbiology — Posted on 2024-07-04
4549 Ancestral SARS-CoV-2 immune imprinting persists on RBD but not NTD after sequential Omicron infections
Wang, Z.; Li, L.; Du, R.; Chen, X.; Sun, Y.; Qin, R.; Li, Y.; Feng, H.; Hu, L.; Chen, X.; Lu, M.; Jiang, L.; Zuo, T.
10.1101/2024.05.30.596664 — immunology — Posted on 2024-07-04
4552 Hypoxia-Inducible Factor-1 activated by PIM1 assembles a non-canonical transcription complex and resultant regulon that drives progression of JAK2V617F myeloproliferative neoplasms
Kealy, D.; Ellerington, R.; Bansal, S.; Zeng, A. G. X.; Medeiros, J. J. F.; West, K. A.; Blacknell, N.-M.; Hawley, C. A.; Lukaszonek, J.; Gawne, R.; Khoo, H. M.; Caalim, G.; Drylie, B.; Chatzigerou, J.; Rodriguez Lima Ferreira, B.; Wang, G.; Fielding, A. K.; Kent, D.; Psaila, B.; Wilkinson, A. C.; Holding, A. N.; Hitchcock, I. S.; Mason, A. S.; Gupta, V.; Dick, J.; Bridge, K. S.
10.1101/2024.07.02.601518 — cancer biology — Posted on 2024-07-04
4553 Transcriptome-wide characterization of genetic perturbations
Nadig, A.; Replogle, J. M.; Pogson, A. N.; McCarroll, S. A.; Weissman, J. S.; Robinson, E. B.; O'Connor, L. J.
10.1101/2024.07.03.601903 — genomics — Posted on 2024-07-03
4554 DNA Methylation of CpG in the Promoter Regions of HIV Coreceptors Related Genes (CCR5 and CXCR4): Original Research
Esman, A.; Salamaikina, S.; Vinokurov, M.; Fomina, D.; Kirichenko, A.; Pokrovskaya, A.; Akimkin, V.
10.1101/2024.07.01.601546 — genetics — Posted on 2024-07-03
4556 Effects of temperature and salinity on microbial degradation of bacterial necromass in urban river sediments in outdoor mesocosm experiments
Hadziomerovic, U.; Baikova, D.; Madge Pimentel, I.; Buchner, D.; Vermiert, A.-M.; Rehsen, P. M.; Brauer, V. S.; Meckenstock, R. U.
10.1101/2024.07.03.601918 — microbiology — Posted on 2024-07-03
4557 Regulation of proteostasis by sleep through autophagy in Drosophila models of Alzheimer's Disease
Ortiz-Vega, N.; Lobato, A. G.; Canic, T.; Zhu, Y.; Lazopulo, S.; Syed, S.; Zhai, R. G.
10.1101/2024.07.01.601554 — neuroscience — Posted on 2024-07-03
4559 Thalamic Control Over Laminar Cortical Dynamics Across Conscious States
Muller, E. J.; Munn, B.; Baracchini, G.; Fulcher, B. D.; Medel, V.; Redinbaugh, M. J.; Saalmann, Y. B.; Brunton, B. W.; Brunton, S. L.; Shine, J.
10.1101/2024.07.02.601788 — neuroscience — Posted on 2024-07-03
4561 Modelling determinants of region-specific dopamine dynamics in the striatum
Ejdrup, A. L.; Dreyer, J. K.; Lycas, M. D.; Jorgensen, S. H.; Robbins, T. W.; Dalley, J. W.; Herborg, F.; Gether, U.
10.1101/2024.07.03.601861 — neuroscience — Posted on 2024-07-03
4562 Familiarity of an environment prevents song suppression in isolated zebra finches
Zai, A. T.; Rodrigues, D. I.; Stepien, A. E.; Adam, I.; Lorenz, C.; Giret, N.; Hahnloser, R. H. R.
10.1101/2024.07.02.601800 — zoology — Posted on 2024-07-03
4564 Induction of intercrypt goblet cells upon bacterial infection
LEONARD, R.; PASQUEREAU KOTULA, E.; MADEC, E.; MARSAC, B.; MIHALACHE, A.; DU MERLE, L.; DENIS, J.; SPRIET, C.; SANSONETTI, P. J.; DRAMSI, S.; ROBBE MASSELOT, C.
10.1101/2024.07.03.601821 — biochemistry — Posted on 2024-07-03
4566 Structural basis of the human transcriptional Mediator complex modulated by its dissociable Kinase module
Chen, S.-F.; Chao, T.-C.; Kim, H. J.; Tang, H.-C.; Khadka, S.; Li, T.; Lee, D.-F.; Murakami, K.; Boyer, T. G.; Tsai, K.-L.
10.1101/2024.07.01.601608 — biochemistry — Posted on 2024-07-03
4568 Tsa1 is the dominant peroxide scavenger and a source of H2O2-dependent GSSG production in yeast
Morgan, B.; Zimmermann, J.; Lang, L.; Calabrese, G.; Laporte, H.; Amponsah, P.; Michalk, C.; Sukmann, T.; Oestreicher, J.; Tursch, A.; Peker, E.; Owusu, T.; Weith, M.; Prates Roma, L.; Deponte, M. q.; Riemer, J.
10.1101/2024.07.03.601836 — biochemistry — Posted on 2024-07-03
4570 Fine-tuning of a CRISPRi screen in the seventh pandemic Vibrio cholerae
Debatisse, K.; Niault, T.; Peeters, S.; Maire, A.; Darracq, B.; Baharoglu, Z.; Bikard, D.; Mazel, D.; Loot, C.
10.1101/2024.07.03.601881 — genetics — Posted on 2024-07-03
4572 Sedentary chromosomal integrons as biobanks of bacterial anti-phage defence systems
Darracq, B.; Littner, E.; Brunie, M.; Bos, J.; Kaminski, P. A.; Depardieu, F.; Slesak, W.; Debatisse, K.; Touchon, M.; Bernheim, A.; Bikard, D.; Le Roux, F.; Mazel, D.; Rocha, E. P.; Loot, C.
10.1101/2024.07.02.601686 — genetics — Posted on 2024-07-03
4573 Phenotypically wild barley shows evidence of introgression from cultivated barley
Liu, C.; Lei, L.; Shao, M.; Franckowiak, J. D.; Pacheco, J. B.; Scott, J. C.; Gavin, R. T.; Roy, J. K.; Sallam, A. H.; Steffenson, B. J.; Morrell, P. L.
10.1101/2024.07.01.601622 — evolutionary biology — Posted on 2024-07-03
4576 Wetland tree barks are dynamic hotspots for microbial trace gas cycling
Leung, P. M.; Jeffrey, L. C.; Bay, S. K.; Gomez-Alvarez, P.; Hall, M.; Johnston, S. G.; Dittmann, J.; Jirapanjawat, T.; Hutchinson, T. F.; Coleman, N. V.; Dong, X.; Deschaseaux, E.; Maher, D. T.; Greening, C.
10.1101/2024.07.02.601631 — microbiology — Posted on 2024-07-03
4578 Competition and cooperation: The plasticity of bacteria interactions across environments
Solowiej-Wedderburn, J.; Pentz, J. T.; Lizana, L.; Schroder, B.; Lind, P.; Libby, E.
10.1101/2024.07.03.601864 — microbiology — Posted on 2024-07-03
4581 Ecology of prophage-like elements in Bacillus subtilis at global and local geographical scale
Stefanic, P.; Stare, E.; Floccari, V. A.; Kovac, J.; Hertel, R.; Rocha, U.; Kovacs, A. T.; Mandic-Mulec, I.; Strube, M. L.; Dragos, A.
10.1101/2024.07.03.601884 — microbiology — Posted on 2024-07-03
4583 Developing, characterizing and modelingCRISPR-based point-of-use pathogen diagnostics
Jung, J. K.; Dreyer, K. S.; Dray, K. E.; Muldoon, J. J.; George, J.; Shirman, S.; Cabezas, M. D.; D'Aquino, A. E.; Verosloff, M. S.; Seki, K.; Rybnicky, G. A.; Alam, K. K.; Bagheri, N.; Jewett, M. C.; Leonard, J. N.; Mangan, N. M.; Lucks, J. B.
10.1101/2024.07.03.601853 — synthetic biology — Posted on 2024-07-03
4585 Effect of truffle extracts on growth of Chlorella vulgaris
VLASOVA, A.; Lipatova, O. E.; Belyshenko, A. Y.; Martynova, E. I.; Imidoeva, N. A.; Telnova, T. Y.; Malygina, E. V.; Morgunova, M. M.; Dmitrieva, M. E.; Shelkovnikova, V. N.; Shashkina, S. S.; Vavilina, T. N.; Axenov-Gribanov, D.
10.1101/2024.07.03.601813 — biochemistry — Posted on 2024-07-03
4590 Spatial proteomic mapping of human nuclear bodies reveals new functional insights into RNA regulation
Dyakov, B. J. A.; Kobelke, S.; Ahmed, B. R.; Wu, M.; Roth, J. F.; Kasmaeifar, V.; Lin, Z.-Y.; Youn, J.-Y.; Thivierge, C.; Campbell, K. R.; Duchaine, T. F.; Blencowe, B. J.; Fox, A. H.; Gingras, A.-C.
10.1101/2024.07.03.601239 — cell biology — Posted on 2024-07-03
4592 Heat pre-treatment reduces multiplicity of plasmid transformations in yeast during electroporation, without diminishing the transformation efficiency
Wäneskog, M.; Hoch-Schneider, E. E.; Garg, S.; Kronborg Cantalapiedra, C.; Schaefer, E.; Krogh Jensen, M.; Damgaard Jensen, E.
10.1101/2024.07.03.601847 — microbiology — Posted on 2024-07-03
4593 Characterizing Excretory-Secretory Products Proteome Across Larval Development Stages in Ascaris suum
Castaneda, S.; Adeniyi-Ipadeola, G.; Wu, Y.; Suarez-Reyes, C.; Jain, A.; Ramirez Gonzalez, J. D.; Weatherhead, J.
10.1101/2024.07.03.601870 — microbiology — Posted on 2024-07-03
4594 Tubulin-Targeted Therapy in Melanoma Increases Cell Invasive Potential by Activation of Actomyosin Cytoskeleton - an in vitro study
Luty, M.; Szydlak, R.; Pabijan, J.; Zemla, J.; Oevreeide, I. H.; Prot, V. E.; Stokke, B. T.; Lekka, M.; Zapotoczny, B.
10.1101/2024.07.01.601575 — biophysics — Posted on 2024-07-03
4595 A Drug-Elicitable Alternative-Splicing Module (DreAM) for Tunable AAV Expression and Controlled Myocardial Regeneration
Chen, Z.; Yang, L.; Zhang, Y.; Li, Y.; Chen, G.; Wang, Z.; Li, J.; Yang, Y.; Zhao, D.; Pu, W. T.; Yang, K.; Dong, E.; Guo, Y.
10.1101/2024.07.01.601517 — bioengineering — Posted on 2024-07-03
4596 Comparison of Infinium MethylationEPIC v2.0 to v1.0 for human population epigenetics: considerations for addressing EPIC version differences in DNA methylation-based tools
Zhuang, B. C.; Jude, M. S.; Konwar, C.; Ryan, C. P.; Whitehead, J.; Engelbrecht, H.-R.; MacIsaac, J. L.; Dever, K.; Toan, T. K.; Korinek, K.; Zimmer, Z.; Huffman, K. M.; Lee, N. R.; McDade, T. W.; Kuzawa, C. W.; Belsky, D. W.; Kobor, M. S.
10.1101/2024.07.02.600461 — genomics — Posted on 2024-07-03
4597 Understanding glycaemia and glycation levels in birds: diet and life history traits associations
Moreno Borrallo, A.; Jaramillo Ortiz, S.; Schaeffer-Reiss, C.; Rey, B.; Quintard, B.; Viblanc, V. A.; Boulinier, T.; Bize, P.; S. Gutierrez, J.; Masero, J. A.; Bertile, F.; Criscuolo, F.
10.1101/2024.07.02.600014 — evolutionary biology — Posted on 2024-07-03
4599 Unexpected diversity and ecological significance of uncultivable large virus-like particles in aquatic environments
Billard, H.; Fuster, M.; Enault, F.; Carrias, J.-F.; Fargette, L.; Carrouee, M.; Desmares, P.; Delmont, T. O.; Bigeard, E.; Tanguy, G.; Nogaret, P.; Baudoux, A.-C.; Christaki, U.; Sime-Ngando, T.; Colombet, J.
10.1101/2024.07.03.599014 — ecology — Posted on 2024-07-03
4602 Reticulate leaf venation in Pilea peperomioides is a Voronoi diagram
Zheng, X.; Venezia, M.; Blum, E.; Pedmale, U. V.; Jackson, D.; Prusinkiewicz, P.; Navlakha, S.
10.1101/2024.07.01.601217 — plant biology — Posted on 2024-07-03
4603 Connexin 43 drives glioblastoma cancer stem cell phenotypes through a WNK lysine-deficient protein kinase 1-c-MYC signaling axis
Mulkearns-Hubert, E. E.; Hajdari, N.; Hong, E. S.; Jacobs, A. P.; Kay, K. E.; Wang, S. Z.; Silver, D. J.; Hubert, C. G.; Lathia, J. D.
10.1101/2024.07.01.601549 — cancer biology — Posted on 2024-07-03
4606 Innate immune system signaling and CD11b+CD11c+CD103+ cell migration to the brain underlie changes in mouse behavior after microbial colonization.
Philip, V.; Kraimi, N.; Zhang, H.; Lu, J.; De Palma, G.; Shimbori, C.; McCoy, K. D.; Hapfelmeier, S.; Schaeren, O. P.; Macpherson, A.; Chirdo, F.; Surette, M. G.; Verdu, E. F.; Liu, F.; Collins, S. M.; Bercik, P.
10.1101/2024.07.03.600853 — animal behavior and cognition — Posted on 2024-07-03
4608 Cryptic recombination and transposition drive structural variation to shape genomic plasticity and life history traits in a host generalist fungal plant pathogen
Derbyshire, M. C.; Newman, T. E.; Khentry, Y.; Michael, P. J.; Bennett, S. J.; Rijal Lamichhane, A.; Graham-Taylor, C.; Chander, S.; Camplone, C.; Vicini, S.; Esquivel-Garcia, L.; Buchwaldt, L.; Coutou, C.; Hegedus, D.; Clarkson, J.; Lindbeck, K.; Kamphuis, L. G.
10.1101/2024.07.02.600549 — genomics — Posted on 2024-07-03
4610 RNA mis-splicing in children with myotonic dystrophy is associated with physical function
Hartman, J. M.; Ikegami, K.; Provenzano, M.; Bates, K.; Butler, A.; Jones, A. S.; Berggren, K. N.; Dekdebrun, J.; McKay, M. J.; Baldwin, J. N.; Cornett, K. M. D.; Burns, J.; Kiefer, M.; Johnson, N. E.; Hale, M. A.; DMCRN,
10.1101/2024.07.03.600889 — genetics — Posted on 2024-07-03
4611 SID-2 localises to extracellular vesicles in parasitic nematodes and does not function in environmental RNAi
Blow, F.; Jeffrey, K.; Wang-Ngai Chow, F.; Nikonorova, I. A.; Barr, M. M.; Cook, A. G.; Prevo, B.; Cheerambathur, D. K.; Buck, A. H.
10.1101/2024.07.03.599821 — evolutionary biology — Posted on 2024-07-03
4612 Specialized signaling centers direct cell fate and spatial organization in a limb organoid model
Skoufa, E.; Zhong, J.; Kahre, O.; Hu, K.; Tsissios, G.; Carrau, L.; Herrera, A.; Dominguez Mantes, A.; Ibeas, A.; Jang, H.; Weigert, M.; La Manno, G.; Lutolf, M. P.; Ros, M.; Aztekin, C.
10.1101/2024.07.02.601324 — developmental biology — Posted on 2024-07-03
4613 Ambivalent partnership of the Drosophila posterior class Hox protein Abdominal-B with the Extradenticle and Homothorax cofactors
Curt, J. R.; Martin, P.; Foronda, D.; Hudry, B.; Kannan, R.; Shetty, S.; Merabet, S.; Saurin, A.; Graba, Y.; Sanchez-Herrero, E.
10.1101/2024.07.03.601496 — developmental biology — Posted on 2024-07-03
4614 The ERK5 MAP kinase regulates annexin complexes and membrane dynamics in embryonic stem cells
Brown, H. A.; Guillet, L.; Williams, C. A.; Shaw, H.; Zhou, H.; Rios-Szwed, D.; Fernandez-Alonso, R.; McMulkin, L.; Stavridis, M. P.; Findlay, G. M.
10.1101/2024.07.03.598211 — developmental biology — Posted on 2024-07-03
4616 Rampant Reticulation in a Rapid Radiation of Tropical Trees - Insights from Inga (Fabaceae)
Schley, R. J.; Pineiro, R.; Nicholls, J. A.; Pezzini, F. F.; Kidner, C.; Farbos, A.; Ringelberg, J. J.; Twyford, A. D.; Dexter, K. G.; Pennington, T.
10.1101/2023.09.12.557345 — evolutionary biology — Posted on 2024-07-03
4617 Defects in exosome biogenesis are associated with sensorimotor defects in zebrafish vps4a mutants
Shipman, A.; Gao, Y.; Liu, D.; Sun, S.; Zang, J.; Sun, P.; Syed, Z.; Bhagavathi, A.; Smith, E.; Erickson, T.; Hill, M.; Neuhauss, S. C.; Sui, S.-F.; Nicolson, T.
10.1101/2024.03.13.584854 — neuroscience — Posted on 2024-07-03
4618 Flexible EMG arrays with integrated electronics for scalable electrode density
Anschutz, P. M.; Zia, M.; Lu, J.; Williams, M. J.; Jacob, A. L.; Sober, S. J.; Bakir, M. S.
10.1101/2024.07.02.601782 — neuroscience — Posted on 2024-07-03
4619 The genetics of fruit skin separation in date palm
Malek, J. A.; Younuskunju, S.; Mayer, K.; Mohamoud, Y. A.; Suhre, K.; Mathew, L. S.
10.1101/2024.07.01.601480 — bioinformatics — Posted on 2024-07-03
4620 Toward a generic feature set defined by consensus peaks as a consistent reference for ATAC-seq data
Meng, Q.; Wu, X.; Zhao, Y.; Chen, W.; Li, C.; Wei, Z.; Li, J.; Xi, X.; Chen, S.; Zhang, C.; Chen, S.; Li, J.; Wang, X.; Jiang, R.; Wei, L.; Zhang, X.
10.1101/2023.05.30.542889 — bioinformatics — Posted on 2024-07-03
4621 A novel induced pluripotent stem cell model of schwann cell differentiation reveals NF2-related gene regulatory networks of the extracellular matrix
Lazaro, O.; Li, S.; Carter, W.; Awosika, O.; Robertson, S.; Hickey, B. E.; Angus, S. P.; House, A.; Clapp, D. W.; Qadir, A. S.; Johnson, T. S.; Rhodes, S. D.
10.1101/2024.05.02.591952 — bioinformatics — Posted on 2024-07-03
4622 Large-scale genome analyses provide insights into Hymenoptera evolution
He, C.; Yang, Y.; Zhao, X.; Li, J.; Cai, Y.; Peng, L.; Liu, Y.; Xiong, S.; Mei, Y.; Yan, Z.; Wang, J.; Xiao, S.; Teng, Z.; Gao, X.; Xue, H.; Fang, Q.; Ye, G.; Ye, X.
10.1101/2024.07.01.601370 — genomics — Posted on 2024-07-03
4623 A High-quality Oxford Nanopore Assembly of the Hourglass Dolphin (Lagenorhynchus cruciger) Genome
McGrath, N.; le Roux, J.; Whibley, A.; Alexander, A.; Stewart, R. O.; Johnstone, M.; Stockin, K. A.; Silander, O. K.
10.1101/2024.05.30.596754 — genomics — Posted on 2024-07-03
4627 Quantification of heterogeneity in human CD8+ T cell responses to vaccine antigens: an HLA-guided perspective
Harris, D. C.; Shanker, A.; Montoya, M. M.; Llewellyn, T. R.; Matuszak, A. R.; Lohar, A.; Kubicek Sutherland, J. Z.; Li, Y. W.; Wilding, K.; Mcmahon, B.; Gnanakaran, S.; Ribeiro, R. M.; Perelson, A. S.; molina-paris, c.
10.1101/2024.07.02.601716 — immunology — Posted on 2024-07-03
4628 Single-cell transcriptomic changes in oligodendrocytes and precursors derived from Parkinson's disease patient-iPSCs with LRRK2-G2019S mutation
Dehestani, M.; Kessler, W.; Karmali, N.; Sun, W.; Tsitkov, S.; Dhingra, A.; Rodriguez-Nieto, S.; Tietz, J.; Schafflick, D.; Fernandes, N.; Fraenkel, E.; Gasser, T.; Kuhlmann, T.; Bansal, V.
10.1101/2024.07.01.601392 — neuroscience — Posted on 2024-07-03
4629 Explicit and implicit locomotor learning in individuals with chronic hemiparetic stroke
Wood, J. M.; Thompson, E. M.; Wright, H.; Festa, L.; Morton, S. M.; Reisman, D. S.; Kim, H. E.
10.1101/2024.02.04.578807 — neuroscience — Posted on 2024-07-03
4631 Neural correlates of nightmares revisited: findings from large-scale fMRI cohorts
Pereira, M.; Terpstra, N.; Rutiku, R.; Sandberg, K.; Dresler, M.; Krause, F.
10.1101/2024.07.02.601684 — neuroscience — Posted on 2024-07-03
4632 Single-cell proteomics of Arabidopsis leaf mesophyll identifies drought stress-related proteins
Fulcher, J. M.; Dawar, P.; Balasubramanian, V. K.; Williams, S. M.; Nadeau, K.; Winkler, T. E.; Markillie, L. M.; Mitchell, H. D.; Ahkami, A. H.; Pasa-Tolic, L.; Zhu, Y.
10.1101/2024.07.01.601628 — plant biology — Posted on 2024-07-03
4633 Molecular control of dormancy transitions throughout the year in the monoecious cork oak
Silva, H. G.; Sobral, R.; Alhinho, A. T. T.; Afonso, H. R.; Ribeiro, T.; Silva, P.; Bousbaa, H.; Morais-Cecilio, L.; Costa, M. M. R.
10.1101/2024.07.03.601814 — plant biology — Posted on 2024-07-03
4634 Reporter-based screening identifies RAS-RAF stabilizing mutations as drivers of resistance to broad-spectrum RAS inhibition in colorectal cancer
Aust, O.; Blanc, E.; Lüthen, M.; Hollek, V.; Astaburuaga-Garcia, R.; Klinger, B.; Trinks, A.; Beule, D.; Papke, B.; Horst, D.; Bluthgen, N.; Sers, C.; Der, C.; Morkel, M.
10.1101/2024.07.01.601542 — cancer biology — Posted on 2024-07-03
4638 Surpassing Light Inhomogeneities in Structured-Illumination Microscopy with FlexSIM
Soubies, E.; Nogueron, A.; Pelletier, F.; Mangeat, T.; Leterrier, C.; Unser, M.; Sage, D.
10.1101/2023.12.20.572677 — biophysics — Posted on 2024-07-03
4641 Microglia Morphological Response to Mesenchymal Stromal Cell Extracellular Vesicles Demonstrates EV Therapeutic Potential for Modulating Neuroinflammation
Daga, K. R.; Larey, A. M.; Morfin, M. G.; Chen, K.; Bitarafan, S.; Carpenter, J. M.; Hynds, H. M.; Hines, K. M.; Wood, L. B.; Marklein, R. A.
10.1101/2024.07.01.601612 — bioengineering — Posted on 2024-07-03
4642 Structural basis for transcription activation through cooperative recruitment of MntR
Shi, H.; Fu, Y.; Kodyte, V.; Andreas, A.; Sachla, A.; Miller, K.; Shrestha, R.; Helmann, J. D.; Glasfeld, A.; Ahuja, S.
10.1101/2024.06.28.601288 — biochemistry — Posted on 2024-07-03
4643 Gene body DNA hydroxymethylation restricts the magnitude of transcriptional changes during aging
Occean, J. R.; Yang, N.; Sun, Y.; Dawkins, M. S.; Munk, R.; Belair, C.; Dar, S.; Anerillas, C.; Wang, L.; Shi, C.; Dunn, C.; Bernier, M.; Price, N. L.; Kim, J. S.; Cui, C.-Y.; Fan, J.; Bhattacharyya, M.; De, S.; Maragkakis, M.; Cabo, R. d.; Sidoli, S.; Sen, P.
10.1101/2023.02.15.528714 — genomics — Posted on 2024-07-03
4644 Mechanistic target of rapamycin (mTOR) pathway in Sertoli cells regulates age-dependent changes in sperm DNA methylation
Amir, S.; Arowolo, O.; Mironova, E.; McGaunn, J.; Oluwayiose, O.; Sergeyev, O.; Pilsner, J. R.; Suvorov, A.
10.1101/2023.05.23.541978 — developmental biology — Posted on 2024-07-03
4646 Design, infectability, and transcriptomic analysis of transregionally differentiated and scalable lung organoids derived from adult bronchial cells.
Reyes Valenzuela, A.; Turner, M.; Markarian, N.; Lachance-Brais, C.; Hanrahan, J. W.; Vali, H.; Vidal, S.; Mongeau, L.
10.1101/2024.07.02.601655 — cell biology — Posted on 2024-07-03
4648 Nepali oral microbiomes reflect a gradient of lifestyles from traditional to industrialized
Ryu, E. P.; Gautam, Y.; Proctor, D. M.; Bhandari, D.; Tandukar, S.; Gupta, M.; Gautam, G. P.; Relman, D. A.; Shibl, A. A.; Sherchand, J. B.; Jha, A. R.; Davenport, E. R.
10.1101/2024.07.01.601557 — microbiology — Posted on 2024-07-03
4650 A spatially resolved multiomic single-cell atlas of soybean development
Zhang, X.; Luo, Z.; Marand, A. P.; Yan, H.; Jang, H.; Bang, S.; Mendieta, J. P.; Minow, M. A. A.; Schmitz, R. J.
10.1101/2024.07.03.601616 — plant biology — Posted on 2024-07-03
4651 CRISPR targeting of FOXL2 c.402C>G mutation reduces malignant phenotype in granulosa tumor cells and identifies anti-tumoral compounds
Amarilla-Quintana, S.; Navarro, P.; Ramos, A.; Montero-Calle, A.; Cabezas-Sainz, P.; Barrero, M. J.; Megias, D.; Vilaplana-Marti, B.; Epifano, C.; Gomez-Dominguez, D.; Hernandez, I.; Monzon, S.; Cuesta, I.; Sanchez, L.; Barderas, R.; Garcia-Donas, J.; Martin, A.; Perez de Castro, I.
10.1101/2024.07.01.601520 — cancer biology — Posted on 2024-07-03
4653 Upregulation of a nonsense mediated decay (NMD) insensitive CFTR mRNA isoform has therapeutic potential for the treatment of 3 Prime CFTR PTC variants
Allaire, N. E.; Armstrong, M.; Yoon, J. S.; Bhatt, P.; Harrington, J.; Cheng, Y.; Valley, H.; Macadino, C.; Bihler, H.; Sivachenko, A.; Mense, M.; Cotton, C.
10.1101/2024.07.01.601512 — genomics — Posted on 2024-07-03
4654 HCV- and HBV-mediated liver cancer converge on similar transcriptomic landscapes and immune profiles.
Borden, E.; Jorgensen, A.; Natri, H. M.; Hastings, K. T.; Buetow, K. H.; Wilson, M. A.
10.1101/2024.07.01.601493 — genetics — Posted on 2024-07-03
4655 Imputation of ancient canid genomes reveals inbreeding history over the past 10,000 years
Bougiouri, K.; Aninta, S. G.; Charlton, S.; Harris, A.; Carmagnini, A.; Piliciauskiene, G.; Feuerborn, T. R.; Scarsbrook, L.; Tabadda, K.; Blazevicius, P.; Parker, H. G.; Gopalakrishnan, S.; Larson, G.; Ostrander, E. A.; Irving-Pease, E. K.; Frantz, L. A. F.; Racimo, F.
10.1101/2024.03.15.585179 — evolutionary biology — Posted on 2024-07-03
4657 Sphingosine kinase 1 is integral for elastin deficiency-induced arterial hypermuscularization
Saito, J.; Dave, J. M.; Gallardo-Vara, E.; Kabir, I.; Tellides, G.; Riemer, R. K.; Urban, Z.; Hla, T.; Greif, D. M.
10.1101/2024.07.01.601150 — developmental biology — Posted on 2024-07-03
4658 A Vago-like gene enhances dengue and Zika virus dissemination in Aedes aegypti
Couderc, E.; Crist, A. B.; Daron, J.; Varet, H.; Van Hout, F. A. H.; Miesen, P.; Palatini, U.; Dabo, S.; Vial, T.; LAMBRECHTS, L.; Merkling, S.
10.1101/2024.07.01.601473 — immunology — Posted on 2024-07-03
4659 Activated NK cells with a predominance of inhibitory receptors and a decidual-like phenotype expand after autologous HSCT in children with tumors.
Astarloa-Pando, G.; Polanco-Alonso, D.; Sanda, V.; Orrantia, A.; Amarilla-Irusta, A.; Perez-Fernandez, S.; Perez-Garay, R.; Sevilla, A.; Lopez-Pardo, A.; Tijero, A.; Uriz, J. J.; Rey, M.; Astigarraga, I.; Manzanares-Martin, B.; Bediaga, N. G.; Amo, L.; Zenarruzabeitia, O.; Borrego, F.
10.1101/2024.07.01.601507 — immunology — Posted on 2024-07-03
4661 The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases uncovers cholesterol as a regulator of astrocyte reactivity impaired by ApoE4
Feringa, F. M.; Koppes-den Hertog, S. J.; Wang, L.; Derks, R. J. E.; Kruijff, I.; Erlebach, L.; Heijneman, J.; Miramontes, R.; Pömpner, N.; Blomberg, N.; Olivier-Jimenez, D.; Johanson, L. E.; Cammack, A. J.; Giblin, A.; Toomey, C. E.; Rose, I. V. L.; Yuan, H.; Ward, M. E.; Isaacs, A.; Kampmann, M.; Kronenberg-Versteeg, D.; Lashley, T.; Thompson, L. M.; Ori, A.; Mohammed, Y.; Giera, M.; van der Kant, R. H. N.
10.1101/2024.07.01.601474 — neuroscience — Posted on 2024-07-03
4665 DWARF14 and KARRIKIN INSENSITIVE2 mediate signaling of the apocarotenoid zaxinone in Arabidopsis
Moreno Beltran, J. C.; Shahul Hameed, U. F.; Balakrishna, A.; Ablazov, A.; Liew, K. X.; Jamil, M.; Mi, J.; Alashoor, K.; de Saint Germain, A.; Arold, S. T.; Al-Babili, S.
10.1101/2024.07.03.601835 — plant biology — Posted on 2024-07-03
4666 DNA methylation database for gynecological cancer detection, classification and assay development
Boers, J.; Boers, R.; Sakoltchik, J.; Dasgupta, S.; Martens, L.; Tadema, K.; Prevoo, F.; Van IJcken, W.; Van den Munckhof, H.; Quint, W.; Van Beekhuizen, H.; Quint, W. H.; Van Kemenade, F.; Gribnau, J.
10.1101/2024.07.01.601485 — cancer biology — Posted on 2024-07-03
4668 Multiplatform molecular profiling and functional genomic screens identify prognostic signatures and mechanisms underlying MEK inhibitor response in somatic NF1 mutant glioblastoma
Pan, S.; Mirchia, K.; Payne, E.; Liu, S. J.; Al-Adli, N.; Peeran, Z.; Shukla, P.; Young, J. S.; Gupta, R.; Wu, J.; Pak, J.; Seo, K.; Ozawa, T.; Na, B.; Reddy, A. T.; Braunstein, S. E.; Phillips, J. J.; Chang, S.; Solomon, D. A.; Perry, A.; Raleigh, D. R.; Berger, M. S.; Abate, A. R.; Vasudevan, H. N.
10.1101/2024.07.01.601334 — genomics — Posted on 2024-07-03
4669 A transphyletic study of metazoan β-catenin protein complexes
Mbogo, I.; Kawano, C.; Nakamura, R.; Tsuchiya, Y.; Villar-Briones, A.; Hirao, Y.; Yasuoka, Y.; Hayakawa, E.; Tomii, K.; Watanabe, H.
10.1101/2024.07.01.600363 — evolutionary biology — Posted on 2024-07-03
4672 Characterisation of aphid antixenosis in aphid-resistant ancestor wheat, Triticum monococcum
Borg, A. N.; Vuts, J.; Caulfield, J. C.; Withall, D. M.; Foulkes, J.; Birkett, M. A.
10.1101/2024.07.01.601505 — ecology — Posted on 2024-07-03
4673 Oviductin sets the species-specificity of the mammalian zona pellucida
de la Fuente, D.; Maroto, M.; Cajas, Y. N.; Canon-Beltran, K.; Fernandez-Gonzalez, R.; Munoz-Maceda, A.; Sanchez-Puig, J. M.; Blasco, R.; Cots, P.; Aviles, M.; Rizos, D.; Gutierrez-Adan, A.
10.1101/2024.07.01.601502 — developmental biology — Posted on 2024-07-03
4676 Fgf23 expression increases atherosclerotic plaque burden in male ApoE deficient mice
Lindberg, K.; Ovchinnikova, O.; Moor, M. B.; Pirault, J.; Ketelhuth, D. F. J.; Olauson, H.; Hansson, G. K.; Larsson, T. E.
10.1101/2024.07.01.601461 — physiology — Posted on 2024-07-03
4677 Development of a Deep Learning model Tailored for HER2 Detection in Breast Cancer to aid pathologists in interpreting HER2-Low cases
Bannier, P.-A.; Broeckx, G.; Herpin, L.; Dubois, R.; Van Praet, L.; Maussion, C.; Deman, F.; Amonoo, E.; Mera, A.; Timbres, J.; Gillett, C.; Sawyer, E.; Gazinska, P.; Ziolkowski, P.; Lacroix-Triki, M.; Salgado, R.; Irshad, S.
10.1101/2024.07.01.601397 — pathology — Posted on 2024-07-03
4680 GenoTools: An Open-Source Python Package for Efficient Genotype Data Quality Control and Analysis
Vitale, D.; Koretsky, M.; Kuznetsov, N.; Hong, S.; Martin, J.; James, M.; Makarious, M. B.; Leonard, H.; Iwaki, H.; Faghri, F.; Blauwendraat, C.; Singleton, A. B.; Song, Y.; Levine, K.; Sreelatha, A. A. K.; Fang, Z.-H.; Nalls, M. A.
10.1101/2024.03.26.586362 — genomics — Posted on 2024-07-03
4681 Dynamics of X chromosome hyper-expression and inactivation in male tissues during stick insect development
Djordjevic, J.; Tran Van, P.; Toubiana, W.; Labedan, M.; Dumas, Z.; Aury, J.-M.; Cruaud, C.; Istace, B.; Labadie, K.; Noel, B.; Parker, D. J.; Schwander, T.
10.1101/2024.07.01.601468 — evolutionary biology — Posted on 2024-07-03
4683 The combination of stimulus-driven and modulatory inputs in visual thalamus depend on visual responsiveness and stimulus type
Schmors, L.; Kotkat, A.; Bauer, Y.; Huang, Z.; Crombie, D.; Meyerolbersleben, L.; Sokoloski, S.; Berens, P.; Busse, L.
10.1101/2023.10.18.562960 — neuroscience — Posted on 2024-07-03
4685 HHV-6B, HHV-7, and B19V Are Frequently Found DNA Viruses in the Human Thymus but Show No Definitive Link with Myasthenia Gravis
NOWLAN, K.; Hannolainen, L.; Assimakopoulou, I. M.; Durnsteiner, P.; Sarkkinen, J.; Suokas, S.; Hedman, L.; Tienari, P. J.; Hedman, K.; Niku, M.; Aaltonen, L.-M.; Huuskanen, A.; Rasanen, J.; Ilonen, I. K.; Mayranpaa, M. I.; Dunkel, J.; Laakso, S. M.; Soderlund-Venermo, M.; Perdomo, M. F.; Kekalainen, E.
10.1101/2024.06.27.600940 — immunology — Posted on 2024-07-03
4689 Insights into the metabolic consequences of type 2 diabetes
Bocher, O.; Singh, A.; Huang, Y.; Vosa, U.; Reimann, E.; Arruda, A.; Barysenska, A.; Kolde, A.; Rayner, N. W.; Esko, T.; Mägi, R.; Zeggini, E.
10.1101/2024.06.20.599832 — genomics — Posted on 2024-07-03
4691 Chromosome X Dosage Modulates Development of Aneuploidy in Genetically Diverse Mouse Embryonic Stem Cells
Stanton, A.; Aydin, S.; Skelly, D. A.; Stavish, D.; Leonhard, K. A.; McIntire, E.; Pankratz, M.; Czechanski, A.; Ludwig, T.; Choi, T.; Gygi, S. P.; Barbaric, I.; Munger, S. C.; Reinholdt, L. G.; PERA, M. F.
10.1101/2024.06.29.601344 — genetics — Posted on 2024-07-03
4696 Unsilenced inhibitory cortical ensemble gates remote memory retrieval
Wang, S.; Sheng, T.; Su, F.; Yang, H.; Cao, R.; Wang, Q.; Zhang, C.; Lu, W.
10.1101/2024.07.01.601454 — neuroscience — Posted on 2024-07-03
4698 1.94 Angstrom structure of synthetic alpha-synuclein fibrils seeding MSA neuropathology
Burger, D.; Kashyrina, M.; Lewis, A. J.; De Nuccio, F.; Mohammed, I.; de La Seigliere, H.; van den Heuvel, L.; Verchere, J.; Feuillie, C.; Berbon, M.; Arotcarena, M.-L.; Retailleau, A.; Bezard, E.; Laferriere, F.; Loquet, A.; Bousset, L.; Baron, T.; Lofrumento, D. D.; De Giorgi, F.; Stahlberg, H.; Ichas, F.
10.1101/2024.07.01.601498 — neuroscience — Posted on 2024-07-03
4699 MICOS Complex Loss Governs Age-Associated Murine Mitochondrial Architecture and Metabolism in the Liver, While Sam50 Dictates Diet Changes
Vue, Z.; Murphy, A. C.; Le, H.; Neikirk, K.; Lopez, E. G.; Marshall, A. G.; Mungai, M.; Jenkins, B. C.; Vang, L.; Beasley, H.; Ezedimma, M.; Manus, S. A.; Whiteside, A.; Forni, M. F.; Harris, C.; Crabtree, A.; Albritton, C. F.; Jamison, S.; Demirci, M.; Prasad, P.; Oliver, A.; Actkins, K.; Shao, J.; Zaganjor, E.; Scudese, E.; Rodriguez, B. I.; Koh, A.; Rabago, I.; Moore, J.; Nguyen, D.; Aftab, M.; Kirk, B.; Li, Y.; Wandira, N.; Ahmad, T.; Saleem, M.; Kadam, A. A.; Katti, P.; Koh, H.-J.; Evans, C.; Koo, Y. D.; Wang, E.; Smith, Q.; Tomar, D.; Williams, C. R.; Sweetwyne, M. T.; Quintana, A.; Phil
10.1101/2024.06.20.599846 — physiology — Posted on 2024-07-03
4700 Phosphodiesterase 3 inhibitors boost bone outgrowth
Kawabe, T.; Ichimura, A.; Yasue, T.; Li, J.; Kim, G. E.; Ishikawa, H.; Ueda, Y.; Itoh, H.; Nishi, M.; Takeshima, H.
10.1101/2024.07.01.601482 — pharmacology and toxicology — Posted on 2024-07-03
4701 Linker histone H1-0 is a specific mediator of the repressive ETV6::RUNX1 transcriptional landscape
Jepsen, V. H.; Hanel, A.; Picard, D.; Mehtonen, J.; Hasselmann, R.; Schliehe-Diecks, J.; Tu, J.-W.; Bhave, R.; Kameri, E.; Qin, N.; Wang, H.; Zhuang, Z.; Wagener, R.; Blümel, L.; Lautwein, T.; Hein, D.; Kögler, G.; Remke, M.; Bhatia, S.; Heinäniemi, M.; Borkhardt, A.; Fischer, U.; Scharov, K.
10.1101/2024.06.28.601221 — cancer biology — Posted on 2024-07-03
4705 The fully activated open state of KCNQ1 controls the cardiac 'fight-or-flight' response
HOU, P.; ZHAO, L.; ZHONG, L.; Shi, J.; WANG, H.; GAO, J.; LIU, H.; Zuckerman, J.; COHEN, I. S.; Cui, J.
10.1101/2024.07.02.601749 — biophysics — Posted on 2024-07-03
4706 FAPM: Functional Annotation of Proteins using Multi-Modal Models Beyond Structural Modeling
Xiang, W.; Xiong, Z.; Huan, C.; Xiong, J.; Zhang, W.; Fu, Z.; Zheng, M.; Liu, B.; Shi, Q.
10.1101/2024.05.07.593067 — bioinformatics — Posted on 2024-07-03
4708 GET: a foundation model of transcription across human cell types
Fu, X.; Mo, S.; Buendia, A.; Laurent, A.; Shao, A.; Alvares-Torres, M. d. M.; Yu, T.; Tan, J.; Su, J.; Sagatelian, R.; Ferrando, A. A.; Ciccia, A.; Lan, Y.; Owens, D. M.; Palomero, T.; Xing, E. P.; Rabadan, R.
10.1101/2023.09.24.559168 — bioinformatics — Posted on 2024-07-03
4719 Unravelling the progression of the zebrafish primary body axis with reconstructed spatiotemporal transcriptomics
Dong, Y.; Cheng, T.; Liu, X.; Fu, X.-x.; Hu, Y.; Yang, X.-F.; Yang, L.; Li, H.-R.; Bian, Z.-W.; JING, N.; Liao, J.; Fan, X.; Xu, P.-F.
10.1101/2024.07.01.601472 — developmental biology — Posted on 2024-07-03
4721 Identification of small molecule agonists of fetal hemoglobin expression for the treatment of sickle cell disease
Yang, J.-P.; Toughiri, R.; Gounder, A.; Scheibe, D.; Petrus, M.; Fink, S.; Vallee, S.; Langston, S.; Kenniston, J.; Papaioannou, N.; Gavva, N.; Horman, S.
10.1101/2024.07.01.601536 — cell biology — Posted on 2024-07-03
4722 Prenylation controls proliferation in human pluripotent stem cell-derived cardiomyocytes
Batho, C.; Reid, J.; Robinson, H.; Cserne Szappanos, H.; Devilee, L.; Hoyte, S.; Johnston, R.; Ziegman, R.; Hassan, S.; Soday, L.; Fitzsimmons, R.; Foster, S.; Ng, D.; Tate, E. W.; Porrello, E. R.; Parker, B.; Mills, R.; Hudson, J. E.
10.1101/2024.07.01.601625 — cell biology — Posted on 2024-07-03
4725 Kingdom-specific lipid unsaturation shapes up sequence evolution in membrane arm subunits of eukaryotic respiratory complexes
Gupta, P.; Chakroborty, S.; Rathod, A. K.; Bhat, S.; Ghosh, S.; Rao T., P.; Nagaraj, R.; Manna, M.; Raychaudhuri, S.
10.1101/2024.07.01.601479 — cell biology — Posted on 2024-07-03
4726 De novo cancer mutations frequently associate with recurrent chromosomal abnormalities during long-term human pluripotent stem cell culture
Al Delbany, D.; Ghosh, M. S.; Krivec, N.; Huyghebaert, A. E.; Regin, M.; Duong, C. M.; Lei, Y.; Sermon, K. D.; Olsen, C.; Spits, C.
10.1101/2024.07.01.601640 — cell biology — Posted on 2024-07-03
4727 Enhancing reproducibility and decentralization in single cell research with biocytometry
Fikar, P.; Alvarez, L.; Berne, L.; Cienciala, M.; Kan, C.; Kasl, H.; Luo, M.; Novackova, Z.; Ordonez, S.; Sramkova, Z.; Holubova, M.; Lysak, D.; Avery, L.; Caro, A. A.; Crowder, R. N.; Diaz-Martinez, L. A.; Donley, D. W.; Giorno, R. R.; Reed, I. K. G.; Hensley, L. L.; Johnson, K. C.; Kim, P.; Kim, A. Y.; LaGier, A. J.; Newman, J. J.; Padilla-Crespo, E.; Reyna, N. S.; Tsotakos, N.; Al-Saadi, N. N.; Appleton, T.; Arosemena-Pickett, A.; Bell, B. A.; Bing, G.; Bishop, B.; Forde, C.; Foster, M. J.; Gray, K.; Hasley, B. L.; Johnson, K.; Jones, D. J.; LaShall, A. C.; McGuire, K.; McNaughton, N.; Morg
10.1101/2024.07.01.601489 — cell biology — Posted on 2024-07-03
4729 Polyamines regulate cell fate by altering the activity of histone-modifying enzymes
Emmons-Bell, M.; Forsyth, G.; Sundquist, A.; Oldeman, S.; Gardikioti, A.; de Souza, R.; Coene, J.; Kamel, M.; Ayyappan, S.; Fuchs, H. A.; Verhelst, S.; Smeeton, J.; Musselman, C. A.; Schvartzman, J. M.
10.1101/2024.07.02.600738 — cell biology — Posted on 2024-07-03
4730 Duodenal organoids from metabolic dysfunction-associated steatohepatitis patients exhibit altered digestive homeostasis
Hadefi, A.; Leprovots, M.; Dinsart, G.; Marefati, M.; Vermeersch, M.; Monteyne, D.; Perez-Morga, D.; Lefort, A.; Libert, F.; Verset, L.; Liefferinckx, C.; Moreno, C.; Jacques, D.; Trepo, E.; Garcia, M.-I.
10.1101/2024.07.02.601648 — cell biology — Posted on 2024-07-03
4733 Large transient assemblies of Apaf1 constitute the apoptosome in cells
Borgeaud, A. C.; Ganeva, I.; Klein, C.; Stooss, A.; Ross-Kaschitza, D.; Wu, L.; Riley, J. S.; Tait, S. W.; Lemmin, T.; Kaufmann, T.; Kukulski, W.
10.1101/2024.07.01.600688 — cell biology — Posted on 2024-07-03
4734 Dsg2 truncation causes a lethal barrier breakdown in mice
Kugelmann, D.; Butz, E. S.; Garcia Ponce, A.; Radeva, M. Y.; Neubauer, J.; Hiermaier, M.; Siadjeu, C.; Burkard, N.; Egu, D.; Horn, A. K. E.; Schmitz, C.; Vuopala, K. S.; Kuismin, O.; Schlegel, N.; Waschke, J.
10.1101/2024.07.01.601522 — cell biology — Posted on 2024-07-03
4737 THE DUAL-SPECIFICITY KINASE DYRK1A INTERACTS WITH THE HEPATITIS B VIRUS GENOME AND REGULATES THE PRODUCTION OF VIRAL RNA
Pastor, F.; Charles, E.; Di Vona, C.; Chapelle, M.; Rivoire, M.; Passot, G.; Chabot, B.; de la Luna, S.; Lucifora, J.; Durantel, D.; Salvetti, A.
10.1101/2024.05.30.596758 — microbiology — Posted on 2024-07-03
4738 NE contribution to rebooting unconsciousness caused by midazolam
Gu, L.; Shao, W.; Liu, L.; Xu, Q.; Wang, Y.; Gu, J.; Yang, Y.; Zhang, Z.; Wu, Y.; Shen, Y.; Yu, Q.; Lian, X.; Ma, H.; Zhang, Y.; Zhang, H.
10.1101/2023.03.20.533578 — neuroscience — Posted on 2024-07-03
4740 Rational Design of Frontline Institutional Phage Cocktail for the Treatment of Nosocomial Enterobacter cloacae Complex Infections
Subedi, D.; Gordillo Altamirano, F. L.; Deehan, R.; Perera, A.; Patwa, R.; Kostoulias, X.; Korneev, D.; Blakeway, L.; Macesic, N.; Peleg, A. Y. L.; Barr, J. J.
10.1101/2024.06.30.601436 — microbiology — Posted on 2024-07-03
4741 Podoplanin Positive Cell-derived Extracellular Vesicles Contribute to Cardiac Amyloidosis After Myocardial Infarction
Kishore, R.; Cimini, M.; Hansmann, U. H. E.; Gonzalez, C.; Chesney, A. D.; Trungcao, M.; Gao, E.; Wang, T.; Roy, R.; Forte, E.; Mallaredy, V.; Gurrala, C. T.; Magadum, A.; Joladarashi, D.; Benedict, C. L.; Koch, W.; Tükel, C.
10.1101/2024.06.28.601297 — immunology — Posted on 2024-07-03
4744 Enhanced purinergic signaling in the paraventricular hypothalamus induces hyperphagic obesity and insulin resistance
Liu, Y.; Zhang, H.; Zhang, Q.; Najam, S. S.; Liang, X.; Sirakawin, C.; Lin, D.; Huang, S.; Bondarenko, A.; Konopka, W.; Zhang, Y.; Zhang, Z.; Wu, S.; Jing, M.; Vinnikov, I. A.
10.1101/2024.07.02.601503 — neuroscience — Posted on 2024-07-03
4747 Transdiagnostic Neurobiology of Social Cognition and Individual Variability as Measured by Fractional Amplitude of Low-Frequency Fluctuation in Schizophrenia and Autism Spectrum Disorders
Bagheri, S.; Yu, J.-C.; Gallucci, J.; Tan, V.; Oliver, L. D.; Dickie, E. W.; Rashidi, A. G.; Foussias, G.; Lai, M.-C.; Buchanan, R. W.; Malhotra, A. K.; Voineskos, A. N.; Ameis, S. H.; Hawco, C.
10.1101/2024.07.02.601737 — neuroscience — Posted on 2024-07-03
4748 Neuronal APOE4-induced Early Hippocampal Network Hyperexcitability in Alzheimers Disease Pathogenesis
Tabuena, D. R.; Jang, S.-S.; Grone, B.; Yip, O.; Aery Jones, E. A.; Blumenfeld, J.; Liang, Z.; Koutsodendris, N.; Rao, A.; Ding, L.; Zhang, A. R.; Hao, Y.; Xu, Q.; Yoon, S. Y.; De Leon, S.; Huang, Y.; Zilberter, M.
10.1101/2023.08.28.555153 — neuroscience — Posted on 2024-07-03
4750 tRNA modification profiling reveals epitranscriptome regulatory networks in Pseudomonas aeruginosa
Sun, J.; Wu, J.; Yuan, Y.; Fan, L.; Chua, W. L. P.; Ling, Y. H. S.; Balamkundu, S.; Dwijapriya, D.; Suen Suen, H. C.; de Crecy-Lagard, V.; Dziergowska, A.; Dedon, P.
10.1101/2024.07.01.601603 — genetics — Posted on 2024-07-02
4752 R(+) Propranolol decreases lipid accumulation in hemangioma-derived stem cells
Tan, J. W. H.; Wylie-Sears, J.; Seebauer, C.; Mulliken, J. B.; Francois, M.; Holm, A.; Bischoff, J.
10.1101/2024.07.01.601621 — molecular biology — Posted on 2024-07-02
4753 Delineation of a thrombin receptor-stimulated vascular smooth muscle cell transition generating cells in the plaque-stabilising fibrous cap
Taylor, J. C.; Worssam, M.; Oc, S.; Lambert, J.; Mahbubani, K. T.; Foote, K.; Finigan, A.; Chan, Y.-H.; Figg, N.; Clarke, M. C.; Bennett, M. R.; Jorgensen, H. F.
10.1101/2024.07.02.600985 — molecular biology — Posted on 2024-07-02
4754 Polyunsaturated Fatty Acid - mediated Cellular Rejuvenation for Reversing Age-related Vision Decline
Gao, F.; Tom, E.; Rydz, C.; Cho, W.; Kolesnikov, A. V.; Sha, Y.; Papadam, A.; Jafari, S.; Joseph, A. P.; Ahanchi, A.; Balalaei Someh Saraei, N.; Lyon, D. C.; Foik, A. T.; Nie, Q.; Grassmann, F.; Kefalov, V.; Skowronska-Krawczyk, D.
10.1101/2024.07.01.601592 — molecular biology — Posted on 2024-07-02
4757 Mobile Integrons Encode Phage Defence Systems
Kieffer, N.; Hipolito, A.; Blanco, P.; Delobelle, T.; Ojeda, F. M.; Jove, T.; Jurenas, D.; Garcia-Quintanilla, M.; Domingo-Calap, P.; Escudero, J. A.
10.1101/2024.07.02.601719 — microbiology — Posted on 2024-07-02
4759 Functional analysis of ESRP1/2 gene variants and CTNND1 isoforms in orofacial cleft pathogenesis
Caetano da Silva, C.; Macias Trevino, C.; Mitchell, J.; Murali, H.; Tsimbal, C.; Dalessandro, E.; Carroll, S. H.; Kochhar, S.; Curtis, S. W.; Cheng, C. H. E.; Wang, F.; Kutschera, E.; Carstens, R. P.; Xing, Y.; Wang, K.; Leslie, E. J.; Liao, E. C.
10.1101/2024.07.02.601574 — genetics — Posted on 2024-07-02
4760 Cytosolic N6AMT1-dependent translation supports mitochondrial RNA processing
Foged, M. M.; Recazens, E.; Chollet, S.; Lisci, M.; Allen, G. E.; Zinshteyn, B.; Boutguetait, D.; Munch, C. A.; Mootha, V. K.; Jourdain, A. A.
10.1101/2024.07.02.601698 — molecular biology — Posted on 2024-07-02
4761 Enhancer-promoter hubs organize transcriptional networks promoting oncogenesis and drug resistance
Perlman, B. S.; Burget, N.; Zhou, Y.; Schwartz, G. W.; Petrovic, J.; Modrusan, Z.; Faryabi, R. B.
10.1101/2024.07.02.601745 — molecular biology — Posted on 2024-07-02
4762 Progerin Can Induce DNA Damage in the Absence of Global Changes in Replication or Cell Proliferation
Joudeh, L. A.; Schuck, P. L.; Van, N. M.; DiCintio, A. J.; Stewart, J. A.; Waldman, A. S.
10.1101/2024.07.02.601729 — molecular biology — Posted on 2024-07-02
4770 Myoferlin is an essential component of late-stage vRNP trafficking vesicles for enveloped RNA viruses.
Bonazza, S.; Turkington, H. L.; Coutts, H. L.; Sukumar, S.; Hawthorn, C.; Getty, E. M. P. E.; Touzelet, O.; Barabas, J.; Power, U.; Courtney, D. G.
10.1101/2024.07.02.601679 — microbiology — Posted on 2024-07-02
4771 Antagonistic effects of actin-specific toxins on Salmonella Typhimurium invasion into mammalian cells
Heisler, D. B.; Kudryashova, E.; Hitt, R.; Williams, B.; Dziejman, M.; Gunn, J. S.; KUDRYASHOV, D. S.
10.1101/2024.07.01.601609 — microbiology — Posted on 2024-07-02
4772 Single-cell transcriptomics highlights sexual cues among reproductive life stages of uncultivated Acantharia (Radiolaria)
Rizos, I.; Romac, S.; Juery, C.; Berthelier, C.; Decelle, J.; Bernardes, J.; Corre, E.; Bittner, L.; Not, F.
10.1101/2024.07.02.601653 — microbiology — Posted on 2024-07-02
4773 Identifying Genetic Variations in emm89 Streptococcus pyogenes Linked to Severe Invasive Infections
Ono, M.; Yamaguchi, M.; Motooka, D.; Hirose, Y.; Higashi, K.; Sumitomo, T.; Miyoshi-Akiyama, T.; Okuno, R.; Yamaguchi, T.; Kawahara, R.; Otsuka, H.; Nakanishi, N.; Kazawa, Y.; Nakagawa, C.; Yamaguchi, R.; Sakai, H.; Matsumoto, Y.; Ikebe, T.; Kawabata, S.
10.1101/2024.07.02.601674 — microbiology — Posted on 2024-07-02
4774 HIV-1 control in vivo is related to the number but not the fraction of infected cells with viral unspliced RNA
Capoferri, A. A.; Wiegand, A.; Hong, F.; Jacobs, J. L.; Spindler, J.; Musick, A.; Bale, M. J.; Shao, W.; Sobolewski, M. D.; Cillo, A. R.; Luke, B. T.; Fennessey, C. M.; Gorelick, R. J.; Hoh, R.; Halvas, E. K.; Deeks, S. G.; Coffin, J. M.; Mellors, J. W.; Kearney, M. F.
10.1101/2024.07.01.601579 — microbiology — Posted on 2024-07-02
4777 Enzyme-Responsive DNA Condensates
Bucci, J.; Malouf, L.; Tanase, D. A.; Farag, N.; Lamb, J. R.; Gentile, S.; Del Grosso, E.; Kaminski, C. F.; Di Michele, L.; Ricci, F.
10.1101/2024.07.02.601714 — synthetic biology — Posted on 2024-07-02
4778 Temporal Image Sandwiches Enable Link between Functional Data Analysis and Deep Learning for Single-Plant Cotton Senescence
DeSalvio, A. J.; Adak, A.; Arik, M. A.; Shepard, N. R.; DeSalvio, S. M.; Murray, S. C.; Garcia-Ramos, O.; Badavath, H.; Stelly, D. M.
10.1101/2024.06.30.601428 — plant biology — Posted on 2024-07-02
4782 Stepwise developmental mimicry generates proximal-biased kidney organoids
Schnell, J.; Miao, Z.; Achieng, M.; Fausto, C. C.; Wang, V.; De Kuyper, F.; Thornton, M. E.; Grubbs, B.; Kim, J.; Lindstrom, N. O.
10.1101/2024.06.28.601028 — developmental biology — Posted on 2024-07-02
4783 IgM plays a prominent role in naturally acquired immunity against Plasmodium falciparum gametocytes
Chan, J.-A.; Lisboa-Pinto, A.; Lu, S.; Harris, A.; Dixon, M. W.; Thomas, A.; Drew, D. R.; Jayakrishnan, N.; Larcher, K.; Naghizadeh, M.; Opi, D. H.; Reiling, L.; Theisen, M.; Chelimo, K.; Kaius-Ome, M.; Mantila, D.; Laman, M.; Robinson, L.; Mueller, I.; King, C. L.; Dent, A.; Kazura, J.; Beeson, J.
10.1101/2024.06.30.601434 — immunology — Posted on 2024-07-02
4786 TGFb-ANGPT2-Tie2 axis in cancer-associated fibroblasts reprograms oral cancer cells to embryonic-like cell state with predictive significance of poor prognosis
Mitra, P.; Saha, U.; Stephen, K. J.; Prasad, P.; Patel, A. K.; Harshvardhan, B. V.; Mondal, S. K.; Kurkalang, S.; Roy, S.; Ghosh, A.; Roy, S. S.; DasSarma, J.; Biswas, N. K.; Acharya, M.; Sharan, R.; Arun, P.; Jolly, M. K.; Maitra, A.; Singh, S.
10.1101/2024.06.29.601319 — cancer biology — Posted on 2024-07-02
4788 GeneLLM: A Large cfRNA Language Model for Cancer Screening from Raw Reads
Deng, S.; Sha, L.; Jin, Y.; Zhou, T.; Wang, C.; Liu, Q.; Guo, H.; Xiong, C.; Xue, Y.; Li, X.; Li, Y.; Gao, Y.; Hong, M.; Xu, J.; Chen, S.; Wang, P.
10.1101/2024.06.29.601341 — bioinformatics — Posted on 2024-07-02
4790 High-Throughput Bioprinting of Spheroids for Scalable Tissue Fabrication
Kim, M. H.; Singh, Y. P.; Celik, N.; Yeo, M.; Rizk, E.; Hayes, D. J.; Ozbolat, I. T.
10.1101/2024.06.30.601432 — bioengineering — Posted on 2024-07-02
4796 Integrin-deficient T cell leukemia accumulates in the central nervous system
Lux, S. Y.; Chen, C.; Subhan, B. S.; Okuniewska, M.; Chung, H.; Vernejoul, J. B.; Martin, K. A.; Caslin, A. Y.; Schiavo, J. K.; Froemke, R.; Cammer, M.; Schwab, S. R.
10.1101/2024.06.28.601274 — immunology — Posted on 2024-07-02
4797 CREB determines the expression of ST2 in Tregs and mediates the balance between type 1 and type 2 immune responses
Hebbar Subramanyam, S.; Hriczko, J.; Look, T.; Goodarzi, T.; Clarner, T.; Verjans, E.; Boell, S.; Neullens, C.; Costa, I.; Gan, L.; Denecke, B.; Schippers, A.; Floess, S.; Huehn, J.; Schmitt, E.; Bopp, T.; Wasmuth, H.; Winograd, R.; Beyaert, R.; Lambrecht, B.; Boor, P.; Zenke, M.; Wagner, N.; Ohl, K.; Tenbrock, K.
10.1101/2024.06.29.601312 — immunology — Posted on 2024-07-02
4800 Anatomical and functional analysis of the corticospinal tract in an FRDA mouse model
Nishiyama, M.; Kalambogias, J.; Imai, F.; Yang, E.; Lang, S.; de Nooij, J. C.; Yoshida, Y.
10.1101/2024.06.28.601178 — neuroscience — Posted on 2024-07-02
4801 Towards a simplified model of primary visual cortex
Du, F.; Nunez-Ochoa, M. A.; Pachitariu, M.; Stringer, C.
10.1101/2024.06.30.601394 — neuroscience — Posted on 2024-07-02
4802 Rod-shaped microglia interact with neuronal dendrites to regulate cortical excitability in TDP-43 related neurodegeneration
Xie, M.; Miller, A.; Pallegar, P.; Umpierre, A.; Liang, Y.; Wang, N.; Zhang, S.; Nagaraj, N.; Zachary, F.; Qi, F.; Ghayal, N.; Oskarsson, B.; Zhao, S.; Zheng, J.; Nguyen, A.; Dickson, D. W.; Wu, L.-J.
10.1101/2024.06.30.601396 — neuroscience — Posted on 2024-07-02
4807 Knock out of the intracellular calcium conducting ion channel Mitsugumin 23 (MG23) protects against pressure overload induced left ventricular hypertrophy and cardiac dysfunction.
Dorward, A. M.; Robertson, G. B.; Sneddon, C.; O'Rourke, C. L.; Um, I. H.; Harrison, D. J.; Nishi, M.; Takeshima, H.; Murdoch, C.; Pitt, S. J.
10.1101/2024.06.28.601299 — physiology — Posted on 2024-07-02
4808 Integrative Imaging of Lung Micro Structure: Amplifying Classical Histology by Paraffin Block μCT and same-slide Scanning Electron Microscopy
Reiser, J.; Albers, J.; Svetlove, A.; Mertiny, M.; Kommoss, F. K.; Schwab, C.; Schneemann, A.; Tromba, G.; Wacker, I.; Curticean, R. E.; Schroeder, R. R.; Kauczor, H.-U.; Wielpuetz, M. O.; Dullin, C.; Wagner, W. L.
10.1101/2024.06.29.601332 — pathology — Posted on 2024-07-02
4812 SPACEc: A Streamlined, Interactive Python Workflow for Multiplexed Image Processing and Analysis
Tan, Y.; Kempchen, T. N.; Becker, M.; Haist, M.; Feyaerts, D.; Xiao, Y.; Su, G.; Rech, A. J.; Fan, R.; Hickey, J. W.; Nolan, G. P.
10.1101/2024.06.29.601349 — bioinformatics — Posted on 2024-07-02
4813 PRISM: Multiplexed Profiling of RNA In-Situ through Single-round of Imaging in Three-Dimensional Tissue
Chang, T.; Zhao, S.; Deng, K.; Liao, Z.; Tang, M.; Zhu, Y.; Han, W.; Yu, C.; Fan, W.; Jiang, M.; Wang, G.; Liu, D.; Peng, J.; Pang, Y.; Fei, P.; Wang, J.; Zheng, C.; Huang, Y.
10.1101/2024.06.29.601330 — bioengineering — Posted on 2024-07-02
4816 Functional monocentricity with holocentric characteristics andchromosome-specific centromeres in a stick insect
Toubiana, W.; Dumas, Z.; Tran Van, P.; Parker, D. J.; Merel, V.; Schubert, V.; Aury, J.-M.; Bournonville, L.; Cruaud, C.; Houben, A.; Istace, B.; Labadie, K.; Noel, B.; Schwander, T.
10.1101/2024.06.30.601385 — evolutionary biology — Posted on 2024-07-02
4817 Selection for early reproduction leads to accelerated aging and extensive metabolic remodeling in Drosophila melanogaster populations
Hubert, D. L.; Arnold, K. R.; Greenspan, Z. G.; Pupo, A.; Robinson, R. D.; Chavarin, V. V.; Barter, T. T.; Djukovic, D.; Raftery, D.; Vue, Z.; Hinton, A.; McReynolds, M. R.; Harrison, B. R.; Phillips, M. A.
10.1101/2024.06.28.601037 — evolutionary biology — Posted on 2024-07-02
4818 Forecasting trade and biosecurity risk under climate change
Camac, J. S.; Cantele, M.; Ha Pham, V.; Li, C.; Robinson, A.; Kompas, T.
10.1101/2024.06.30.601437 — ecology — Posted on 2024-07-02
4820 Analysing bird population trends from monitoring data with highly structured sampling designs
Rieger, M. R.; Grueneberg, C.; Oberhaus, M.; Trautmann, S.; Parepa, M.; Anthes, N.
10.1101/2024.06.30.601382 — ecology — Posted on 2024-07-02
4821 The inflammasome adaptor pycard is essential for immunity against Mycobacterium marinum infection in adult zebrafish
Uusi-Mäkelä, M.; Harjula, S.-K. E.; Junno, M.; Sillanpää, A.; Nätkin, R.; Niskanen, M. T.; Nykter, M.; Rämet, M.
10.1101/2024.06.28.601189 — immunology — Posted on 2024-07-02
4822 Autoimmunity and clinical pathology amelioration in SLE by Dexamethasone primed Mesenchymal Stem Cell derived conditioned media
priya, K.; Rawat, S.; Das, D.; Chaubey, M.; Thacker, H.; Giri, K.; Singh, S.; Rai, M.; Mohanty, S.; Rai, G.
10.1101/2024.06.29.601320 — immunology — Posted on 2024-07-02
4824 Assessing data quality on fetal brain MRI reconstruction: a multi-site and multi-rater study
Sanchez, T.; Mihailov, A.; Gomez, Y.; Marti-Juan, G.; Eixarch, E.; Jakab, A.; Dunet, V.; Koob, M.; Auzias, G.; Bach Cuadra, M.
10.1101/2024.06.28.601169 — neuroscience — Posted on 2024-07-02
4826 Layer-specific reorganization of mnemonic representations in primate retrosplenial cortex during learning
KAMBI, N. A.; Afrasiabi, M. A.; Phillips, J. M.; Kenchappa, S. C.; Cleveland, D.; Redinbaugh, M. J.; Mohanta, S.; Wang, B.; Fayyad, M.; Saalmann, Y. B.
10.1101/2024.06.30.601381 — neuroscience — Posted on 2024-07-02
4831 NREM sleep brain networks modulate cognitive recovery from sleep deprivation
Lee, K.; Wang, Y.; Cross, N.; Jegou, A.; Razavipour, F.; Pomares, F. B.; Perrault, A. A.; Nguyen, A.; Aydin, U.; Uji, M.; Abdallah, C.; Anticevic, A.; Frauscher, B.; Benali, H.; Dang-vu, T. T.; Grova, C.
10.1101/2024.06.28.601285 — neuroscience — Posted on 2024-07-02
4834 Pancreatic islets undergo functional and morphological adaptation during development of Barth Syndrome
Carlein, C.; Hoffmann, M. D.; Amaral, A. G.; Bickelmann, C.; Lotfinia, A.; de Selliers, L.-A.; Audouze-Chaud, J.; Wrublewsky, S.; Lauterbach, M. A.; von der Malsburg, K.; van der Laan, M.; Bozem, M.; Hoth, M.; Gilon, P.; Ravier, M.; Morgan, B.; Ampofo, E.; Maack, C.; Prates Roma, L.
10.1101/2024.06.28.601122 — physiology — Posted on 2024-07-02
4836 The oncofetal protein IMP1 regulates the transcriptomic landscape to drive early events in pancreatic cancer progression and growth
Hacariz, O.; Messina-Pacheco, J.; Goodfellow, E.; Leibovitch, M.; Lowy, A.; Perrino, S.; Jean-Claude, B.; Gao, Z.-H.; Gregorieff, A.; Brodt, P.
10.1101/2024.06.28.601273 — cancer biology — Posted on 2024-07-02
4838 FLT3 is genetically essential for ITD-mutated leukemic stem cells but dispensable for human hematopoietic stem cells
Araujo, J. L.; Wagenblast, E.; Voisin, V.; McLeod, J.; Gan, O. I.; Bansal, S.; Jin, L.; Mitchell, A.; Gratton, B.; Cutting, S.; Arruda, A.; Doedens, M.; Capo-Chichi, J.-M.; Abelson, S.; Minden, M. D.; Wang, J. C.; Sobrinho-Simoes, M. A.; Pinto-do-O, P.; Lechman, E.; Dick, J. E.
10.1101/2024.06.30.601363 — cancer biology — Posted on 2024-07-02
4839 Combined HDAC and eIF4A inhibition: A novel epigenetic therapy for pancreatic adenocarcinoma
Safari, M.; Scotto, L.; Basseville, A.; Litman, T.; Xue, H.; Petrukhin, L.; Zhou, P.; Morales, D. V.; Damoci, C.; Zhu, M.; Hull, K.; Olive, K. P.; Fojo, T.; Romo, D.; Bates, S. E.
10.1101/2024.06.30.600495 — cancer biology — Posted on 2024-07-02
4840 Cellular Dynamics Upon Immune Checkpoint Inhibition
Lin, Z.; Petrenko, E.; Chandra, M.; Srinivas, N.; Ugurel, S.; Becker, J.; Aran, D.
10.1101/2024.06.30.601413 — cancer biology — Posted on 2024-07-02
4841 Dynamic Localization of Leukemia Stem Cells via CXCL12 Regulates Leukemia Progression
Wang, C.; Pan, Y.; Dong, R.; Zhou, W.; Meng, X.; Shi, Y.; Nistala, R.; Hammer, R.; Li, L.; Kang, X.
10.1101/2024.06.29.601323 — cancer biology — Posted on 2024-07-02
4842 The Mammalian KU70 C-terminus SAP Domain Is Required to Repair Exogenous DNA Damage
Wang, Y.; Czap, M.; Kim, H.; Lu, H.; Liu, J.; Chang, Y.; Romanienko, P.; Montagna, C.; Shen, Z.
10.1101/2024.06.30.601420 — cancer biology — Posted on 2024-07-02
4844 StarSignDNA: Signature tracing for accurate representation of mutational processes
Bope, c. D.; Kalyanasundaram, S.; Rand, K. D.; Lingjaerde, O. C.; Hovig, E.; Nakken, S.
10.1101/2024.06.29.601345 — bioinformatics — Posted on 2024-07-02
4846 e3SIM: epidemiological-ecological-evolutionary simulation framework for genomic epidemiology
Xu, P.; Liang, S.; Hahn, A.; Zhao, V.; Lo, W. T. J.; Haller, B. C.; Sobkowiak, B.; Chitwood, M. H.; Colijn, C.; Cohen, T.; Rhee, K. Y.; Messer, P. W.; Wells, M. T.; Clark, A. G.; Kim, J.
10.1101/2024.06.29.601123 — bioinformatics — Posted on 2024-07-02
4852 The role of LEDGF in transcription is exploited by HIV-1 to position integration
Pathak, R.; Esnault, C.; Radhakrishnan, R.; Singh, P. K.; Hongen, H.; Dale, R. K.; Anand, A.; Bedwell, G. J.; Engelman, A.; Rabi, A.; Hormoz, S.; Singh, P.; Levin, H. L.
10.1101/2024.06.29.601340 — genomics — Posted on 2024-07-02
4854 Population genetic consequences of the seasonal migrations of birds
Pegan, T.; Kimmitt, A. A.; Benz, B. W.; Weeks, B. C.; Aubry, Y.; Burg, T.; Hudon, J.; Jones, A. W.; Kirchman, J. J.; Ruegg, K.; Winger, B.
10.1101/2024.06.28.601242 — evolutionary biology — Posted on 2024-07-02
4856 Density-dependent network structuring within and across wild animal systems
Albery, G. F.; Becker, D. J.; Firth, J. A.; Silk, M.; Sweeny, A. R.; Wal, E. V.; Webber, Q.; Allen, B.; Babayan, S. A.; Barve, S.; Begon, M.; Birtles, R. J.; Block, T. A.; Block, B. A.; Bradley, J. E.; Budischak, S.; Buesching, C.; Burthe, S. J.; Carlisle, A. B.; Caselle, J. E.; Cattuto, C.; Chaine, A. S.; Chapple, T.; Cheney, B. J.; Clutton-Brock, T.; Collier, M.; Curnick, D. J.; Delahay, R. J.; Farine, D. R.; Fenton, A.; Ferretti, F.; Fielding, H.; Foroughirad, V.; Frere, C.; Gardner, M. G.; Geffen, E.; Godfrey, S. S.; Graham, A. L.; Hammond, P. S.; Henrich, M.; Heurich, M.; Hopwood, P.; Ila
10.1101/2024.06.28.601262 — ecology — Posted on 2024-07-02
4859 Spatial structure affects the establishment and persistence of closed microbial ecosystems
Mansour, I.; Hähnlein, M.; Minkewitz, L.; Wilk, E. N.; Remus-Emsermann, M.; Antonovics, J.; Matthias, R. C.
10.1101/2024.06.28.601237 — ecology — Posted on 2024-07-02
4860 Phylogenetic and non-phylogenetic patterns in the richness, frequency and composition of links in a herbivore-parasitoid interaction network
Sinclair, F. H.; Tang, C.-T.; Bailey, R. A.; Csoka, G. L.; Melika, G.; Nicholls, J. A.; Nieves-Aldrey, J.-L.; Reiss, A.; Zhang, Y. M.; Phillimore, A.; Schonrogge, K.; Stone, G. N.
10.1101/2024.06.30.601383 — ecology — Posted on 2024-07-02
4861 Phospholipase Cgamma regulates lacrimal gland branching by competing with PI3K in phosphoinositide metabolism
Wang, Q.; Tao, C.; Wu, Y.; Anderson, K. E.; Hannan, A.; Lin, C.-s.; Hawkins, P. T.; Stephens, L.; Zhang, X.
10.1101/2024.06.28.601066 — developmental biology — Posted on 2024-07-02
4864 Anti-diabetic and anti-adipogenic effects of polyherbal formulation Varanadi kashayam with a focus on incretin modulation
Thottappillil, A.; Kouser, S.; Badiger, A. V.; Pinto, P. G.; Ramachandran, S.; Janadri, S.; Mudagal, M. P.; Kukkupuni, S. K.; Mohan S, S.; Chethala N, V.
10.1101/2024.06.29.601306 — cell biology — Posted on 2024-07-02
4865 PTEN Regulates Myofibroblast Activation in Valvular Interstitials Cells based on Subcellular Localization
Batan, D.; Tseropoulos, G.; Bishop, C.; Kirkpatrick, B. E.; Bera, K.; Khang, A.; Weiser-Evans, M. C.; Anseth, K. S.
10.1101/2024.06.30.601424 — cell biology — Posted on 2024-07-02
4866 Reorganization of the Flagellum Scaffolding Induces a Sperm Standstill During Fertilization
Jablonski, M.; Luque, G. M.; Gomez-Elias, M.; Sanchez-Cardenas, C.; Xu, X.; de la Vega-Beltran, J. L.; Corkidi, G.; Linares, A.; Abonza, V.; Arenas-Hernandez, A.; Ramos-Godinez, M. D. P.; Lopez-Saavedra, A.; Krapf, D.; Krapf, D.; Darszon, A.; Guerrero, A.; Buffone, M. G.
10.1101/2023.06.22.546073 — cell biology — Posted on 2024-07-02
4868 Distinct Mechanisms of T3SS Recognition Control LTB4 Synthesis in Neutrophils versus Macrophages
Brady, A.; Mora Martinez, L. C.; Hammond, B.; Bodduluri, H.; Uriarte, S. M.; Lawrenz, M. B.
10.1101/2024.07.01.601466 — immunology — Posted on 2024-07-02
4872 Neural Stem Cell Relay from B1 to B2 cells in the adult mouse Ventricular-Subventricular Zone
Cebrian-Silla, A.; Assis Nascimento, M.; Mancia Leon, W.; Gonzalez-Granero, S.; Romero-Rodriguez, R.; Obernier, K.; Steffen, D. M.; Lim, D. A.; Garcia-Verdugo, J. M.; Alvarez-Buylla, A.
10.1101/2024.06.28.600695 — neuroscience — Posted on 2024-07-02
4878 Ultradian rhythms of CRHPVN neuron activity, behaviour and stress hormone secretion
Zheng, S.; Focke, C. M. B.; Young, C. K.; Tripp, I.; Ganeshan, D.; Power, E.; Schwenke, D. O.; Herbison, A.; Kim, J. S.; Iremonger, K. J.
10.1101/2024.06.30.601439 — neuroscience — Posted on 2024-07-02
4881 Iron deprivation activates aboveground cell wall biosynthesis in Populus and the role of PtrbHLH011
Tadesse, D.; Dai, Y.; Yang, L.; Yang, Y.; Dwivedi, N.; Kumaran, D.; Blaby-Haas, C.; Lipzen, A. M.; Santiago, K.; Barry, K. W.; Liu, C.-J.; Xie, M.
10.1101/2024.06.28.601228 — plant biology — Posted on 2024-07-02
4882 Berberine Bridge enzyme-like oxidases orchestrate homeostatic control and signaling of oligogalacturonides in defense and wounding
Salvati, A.; Diomaiuti, A.; Locci, F.; Gravino, M.; Gramegna, G.; Ilyas, M.; Benedetti, M.; Costantini, S.; De Caroli, M.; Castel, B.; Jones, J. D.; Cervone, F.; Pontiggia, D.; De Lorenzo, G.
10.1101/2024.06.28.601198 — plant biology — Posted on 2024-07-02
4885 Label-Free Melanoma Phenotype Classification Using Artificial Intelligence-Based Morphological Profiling
Lattmann, E.; Jovic, A.; Kim, J.; Pham, T.; Corona, C.; Lian, Z.; Saini, K.; Ray, M.; Lu, V.; Tastanova, A.; Boutet, S. C.; Levesque, M. P.
10.1101/2024.06.28.601235 — cancer biology — Posted on 2024-07-02
4888 Maloja: simple and scalable Snakemake workflow orchestration in the cloud
Giustizia, J.; Hodgson, W.; Andress, C.; Bilkhu, S.; Macklin, J.; Kess, T.
10.1101/2024.06.28.601236 — bioinformatics — Posted on 2024-07-02
4889 Active surveillance for influenza A virus in swine reveals within-farm reassortment and cocirculation of distinct subtypes and genetic clades
Thomas, M. N.; Janzen, G. M.; Markin, A. K.; Sharma, A.; Hewitt, K. S.; Li, G.; Baker, A. L.; Gauger, P. C.; Anderson, T. K.
10.1101/2024.06.28.601245 — bioinformatics — Posted on 2024-07-02
4892 Atf4 protects islet beta-cell identity and function under acute glucose-induced stress but promotes beta-cell failure in the presence of free fatty acid
Yagan, M.; Najam, S.; Hu, R.; Wang, Y.; DAdi, P.; Xu, Y.; Simmons, A. J.; Stein, R.; Adams, C. M.; Jacobson, D. J.; Lau, K.; Liu, Q.; Gu, G.
10.1101/2024.06.28.601249 — genetics — Posted on 2024-07-02
4894 Characterization of Multicellular Niches Supporting Hematopoietic Stem Cells Within Distinct Zones
Dong, R.; Li, H.; He, X. C.; Wang, C.; Perera, A.; Malloy, S.; Russell, J.; Li, W.; Petentler, K.; Mao, X.; Yang, Z.; Epp, M.; Hall, K.; Scott, A.; Smith, S.; Hembree, M.; Wang, Y.; McKinney, S.; Haug, J.; Unruh, J.; Slaughter, B.; Kang, X.; Li, L.
10.1101/2024.06.28.601225 — developmental biology — Posted on 2024-07-02
4895 TSC2 loss in neural progenitor cells suppresses translation of ASD/NDD-associated transcripts in an mTORC1- and MNK1/2-reversible fashion
Martin, P.; Szkop, K.; Robert, F.; Bhattacharyya, S.; Beauchamp, R.; Brenner, J.; Redmond, N.; Huang, S.; Erdin, S.; Larsson, O.; Ramesh, V.
10.1101/2024.06.04.597393 — molecular biology — Posted on 2024-07-02
4896 Target-agnostic identification of human antibodies to Plasmodium falciparum sexual forms reveals cross stage recognition of glutamate-rich repeats
Amen, A.; Yoo, R.; Fabra-Garcia, A.; Bolscher, J.; Stone, W. J. R.; Bally, I.; Dergan-Dylon, S.; Kucharska, I.; de Jong, R. M.; de Bruijni, M.; Bousema, T.; King, C. R.; MacGill, R. S.; Sauerwein, R. W.; Julien, J.-P.; Poignard, P.; Jore, M. M.
10.1101/2023.11.03.565335 — immunology — Posted on 2024-07-02
4898 Glutathione Oxidation in Cerebrospinal Fluid as a Biomarker of Oxidative Stress in Amyotrophic Lateral Sclerosis
Pham, T. K.; Verber, N.; Turner, M. R.; Malaspina, A.; Collins, M. O.; Mead, R. J.; Shaw, P. J.
10.1101/2024.07.01.601162 — neuroscience — Posted on 2024-07-02
4899 Evolution of Opsin Genes in Caddisflies (Insecta: Trichoptera)
Powell, A.; Heckenhauer, J.; Pauls, S. U.; Rios-Touma, B.; Kuranishi, R. B.; Holzenthal, R. W.; Razuri-Gonzales, E.; Bybee, S.; Frandsen, P. B.
10.1101/2023.12.15.571940 — genomics — Posted on 2024-07-02
4900 The sensory shark: high-quality morphological, genomic and transcriptomic data for the small spotted catshark Scyliorhinus canicula reveal the molecular bases of sensory organ evolution in jawed vertebrates
Mayeur, H.; Leyhr, J.; Mulley, J.; Nicolas, L.; Michel, L.; Sharma, K.; Lagadec, R.; Aury, J.-M.; Osborne, O. G.; Mulhair, P.; Poulain, J.; Mangenot, S.; Mead, D.; Smith, M.; Corton, C.; Oliver, K.; Skelton, J.; Betteridge, E.; Dolucan, J.; Dudchenko, O.; Omer, A.; Weisz, D.; Lieberman-Aiden, E.; McCarthy, S.; Sims, Y.; Torrance, J.; Tracey, A.; Howe, K.; Baril, T.; Hayward, A.; Martinand-Mari, C.; Sanchez, S.; Haitina, T.; Martin, K. J.; MAZAN, S.; Korsching, S. I.; Debiais-Thibaud, M.
10.1101/2024.05.23.595469 — evolutionary biology — Posted on 2024-07-02
4904 An Artificial Intelligence Model for Profiling the Landscape of Antigen-binding Affinities of Massive BCR Sequencing Data
Song, B.; Wang, K.; Na, S.; Yao, J.; Fattah, F. J.; von Itzstein, M. S.; Yang, D. M.; Liu, J.; Xue, Y.; Liang, C.; Guo, Y.; Raman, I.; Zhu, C.; Dowell, J. E.; Homsi, J.; Rashdan, S.; Yang, S.; Gwin, M. E.; Hsiehchen, D.; Gloria-McCutchen, Y.; Raj, P.; Bai, X.; Wang, J.; Conejo-Garcia, J.; Xie, Y.; Gerber, D. E.; Huang, J.; Wang, T.
10.1101/2024.06.27.601035 — immunology — Posted on 2024-07-02
4905 SLAM/SAP signaling regulates discrete γδ T cell developmental checkpoints and shapes the innate-like γδ TCR repertoire
Mistri, S. K.; Hilton, B. M.; Horrigan, K. J.; Andretta, E. S.; Savard, R.; Dienz, O.; Hampel, K. J.; Gerrard, D. L.; Rose, J. T.; Sidiropoulos, N.; Majumdar, D.; Boyson, J. E.
10.1101/2024.01.10.575073 — immunology — Posted on 2024-07-02
4906 T cells Instruct Immune Checkpoint Inhibitor Therapy Resistance in Tumors Responsive to IL-1 and TNFa Inflammation.
Cho, N. W.; Guldberg, S. M.; Nabet, B. Y.; Yu, J. Z.; Kim, E. J.; Hiam-Galvez, K. J.; Yee, J. L.; DeBarge, R.; Tenvooren, I.; Ashitey, N. A.; Lynce, F.; Dillon, D. A.; Rosenbluth, J. M.; Spitzer, M. H.
10.1101/2022.09.20.508732 — immunology — Posted on 2024-07-02
4907 Dopamine D1 receptor expression in dlPFC inhibitory parvalbumin neurons may contribute to higher visuospatial distractibility in marmosets versus macaques
Joyce, M. K. P.; Ivanov, T. G.; Krienen, F.; Mitchell, J.; Ma, S.; Inoue, W.; Nandy, A. P.; Datta, D.; Duque, A.; Arellano, J. I.; Gupta, R.; Gonzalez-Burgos, G.; Lewis, D. A.; Sestan, N.; McCarroll, S. A.; Martinez-Trujillo, J. C.; Froudist-Walsh, S.; Arnsten, A. F.
10.1101/2024.06.15.599163 — neuroscience — Posted on 2024-07-02
4911 Senolytic Intervention Improves Cognition, Metabolism, and Adiposity in Female APPNL-F/NL-F Mice.
Fang, Y.; Peck, M. R.; Quinn, K.; Chapman, J. E.; Medina, D.; McFadden, S. A.; Bartke, A.; Hascup, K. N.; Hascup, E. R.
10.1101/2023.12.12.571277 — neuroscience — Posted on 2024-07-02
4912 Transpirational water loss from flowers is low but unregulated
Roddy, A.; Schreel, J.; Paiva, D.; Qin, N.; Jiang, G.-F.; Brodersen, C. R.; Simonin, K.
10.1101/2024.06.28.600864 — plant biology — Posted on 2024-07-02
4913 Sympathetic neuron-derived NPY protects from obesity by sustaining the mural progenitors of thermogenic adipocytes.
Zhu, Y.; Yao, L.; Gallo-Ferraz, A. L.; Bombassaro, B.; Simoes, M. R.; Abe, I.; Chen, J.; Sarker, G.; Ciccarelli, A.; Lee, C.; Martinez-Sanchez, N.; Dustin, M.; Anderson, K.; Zhan, C.; Horvath, T.; Velloso, L.; Kajimura, S.; Domingos, A. I.
10.1101/2024.05.18.594804 — physiology — Posted on 2024-07-02
4914 In vitro genotoxic and mutagenic potentials of combustion particles from marine fuels with different sulfur contents
Jeong, S.; Pantzke, J.; Offer, S.; Kaefer, U.; Bendl, J.; Saraji-Bozorgzad, M.; Huber, A.; Michalke, B.; Etzien, U.; Jacobi, G.; Orasche, J.; Czech, H.; Rueger, C. P.; Schnelle-Kreis, J.; Streibel, T.; Buchholz, B.; Adam, T.; Sklorz, M.; Di Bucchianico, S.; Zimmermann, R.
10.1101/2024.06.27.601016 — pharmacology and toxicology — Posted on 2024-07-02
4916 circPCMTD1: A protein-coding circular RNA that regulates DNA damage response in BCR/ABL-positive leukemias
Papaioannou, D.; Urs, A. P.; Buisson, R.; Petri, A.; Kulkarni, R.; Nicolet, D.; Woodward, L.; Goda, C.; Mrozek, K.; Behbehani, G. K.; Kauppinen, S.; Eisfeld, A.-K.; Aifantis, I.; Singh, G.; Dorrance, A. M.; Garzon, R.
10.1101/2024.06.27.601046 — cancer biology — Posted on 2024-07-02
4917 Lineage-dependence of the neuroblastoma surfaceome defines tumor cell state-dependent and independent immunotherapeutic targets
Kendsersky, N. M.; Odrobina, M.; Mabe, N. W.; Farrel, A.; Grossmann, L.; Tsang, M.; Wolpaw, A. J.; Zammarchi, F.; van Berkel, P. H.; Dang, C. V.; Mosse, Y. P.; Stegmaier, K.; Maris, J.
10.1101/2024.06.27.600865 — cancer biology — Posted on 2024-07-02
4918 The m6A reader IGF2BP3 promotes gastric cancer progression via increasing the expression of FBXO32 protein
Si, Y.; Tian, B.; Zhang, R.; Xuan, M.; Liu, K.; Jiao, J.; Han, S.; Li, H.; Hu, Y.; Zhao, H.; He, W.; Wang, J.; Liu, T.; Yu, W.
10.1101/2024.06.28.601102 — cancer biology — Posted on 2024-07-02
4919 EstroGene2.0: A multi-omic database of response to estrogens, ER-modulators, and resistance to endocrine therapies in breast cancer
Li, Z.; Chen, F.; Chen, L.; Liu, J.; Tseng, D.; Hadi, F.; Omarjee, S.; Kishore, K.; Kent, J.; Kirkpatrick, J.; DSantos, C.; Lawson, M.; Gertz, J.; Sikora, M. J.; McDonnell, D. J.; Carroll, J.; Polyak, K.; Oesterreich, S.; LEE, A. V.
10.1101/2024.06.28.601163 — cancer biology — Posted on 2024-07-02
4920 Dynamic regions allosterically connect the USP14 active site with the proteasome interaction surface
Salomonsson, J.; Sjostrand, L.; Eskilson, A.; Derbyshire, D.; D'Arcy, P.; Sunnerhagen, M.; Ahlner, A.
10.1101/2024.06.28.601165 — biophysics — Posted on 2024-07-02
4923 Ultrafast and accurate sequence alignment and clustering of viral genomes
Zielezinski, A.; Gudys, A.; Barylski, J.; Siminski, K.; Rozwalak, P.; Dutilh, B. E.; Deorowicz, S.
10.1101/2024.06.27.601020 — bioinformatics — Posted on 2024-07-02
4924 Critical roles of Ikaros and HDAC1 in regulation of heterochromatin and tumor suppression in T-cell acute lymphoblastic leukemia
Ding, Y.; He, B.; Bogush, D.; Schramm, J.; Singh, C.; Dovat, K.; Randazzo, J.; Tukaramrao, D.; Hengst, J.; Annageldiyev, C.; Kudva, A.; Desai, D.; Sharma, A.; Spiegelman, V. S.; Huang, S.; Viet, C. T.; Dorsam, G.; Saulnier Scholler, G.; Broach, J.; Yue, F.; Dovat, S.
10.1101/2024.06.27.600861 — bioinformatics — Posted on 2024-07-02
4925 spatialGE: A user-friendly web application to democratize spatial transcriptomics analysis
Ospina, O. E.; Manjarres-Betancur, R.; Gonzalez-Calderon, G.; Soupir, A. C.; Smalley, I.; Tsai, K. Y.; Markowitz, J.; Vallebuona, E.; Berglund, A.; Eschrich, S. A.; Yu, X.; Fridley, B. L.
10.1101/2024.06.27.601050 — bioinformatics — Posted on 2024-07-02
4927 Read Length Dominates Phylogenetic Placement Accuracy of Ancient DNA Reads
Bettisworth, B.; Psonis, N.; Poulakakis, N.; Pavlidis, P.; Stamatakis, A.
10.1101/2024.06.28.601240 — bioinformatics — Posted on 2024-07-02
4929 Joint and tissue mechanics in post-traumatic osteoarthritis: insights from the rat model
Piet, J.; Elahi, S. A.; Esrafilian, A.; Mielke, F.; Van Nuffel, M.; Orozco, G. A.; Vancleef, S.; Lories, R.; Korhonen, R. K.; Aerts, P.; Van Wassenbergh, S.; Jonkers, I.
10.1101/2024.06.27.601039 — bioengineering — Posted on 2024-07-02
4930 IGF-1 Peptide Mimetic-functionalized Hydrogels Enhance MSC Survival and Immunomodulatory Activity
Tan, X.; Jing, L.; Neal, S. M.; Gupta, M. C.; Buchowski, J. M.; Setton, L. A.; Huebsch, N.
10.1101/2024.06.27.600680 — bioengineering — Posted on 2024-07-02
4939 An applicable and efficient retrograde monosynaptic circuit mapping tool for larval zebrafish
Chen, T.; Deng, Q.; Lin, K.; Zheng, X.; Wang, X.; Zhong, Y.; Ning, X.; Li, Y.; Xu, F.; Du, J.; Du, X.
10.1101/2024.06.27.601104 — neuroscience — Posted on 2024-07-02
4941 Differential expression ofCCD4(4B) drives natural variation in fruit carotenoidcontent in strawberry ( Fragaria spp.)
Amaya, I.; Roldan-Guerra, F. J.; Ordonez, J. L.; Torreblanca, R.; Wagner, H.; Waurich, V.; Olbricht, K.; Moreno-Rojas, J. M.; Sanchez Sevilla, J. F.; CASTILLEJO, C.
10.1101/2024.07.02.601541 — plant biology — Posted on 2024-07-02
4942 Deep mutational scanning reveals sequence to function constraints for SWEET family transporters
Narayanan, K.; Weigle, A. T.; Xu, L.; Mi, X.; Zhang, C.; Chen, L.-Q.; Procko, E.; Shukla, D.
10.1101/2024.06.28.601307 — plant biology — Posted on 2024-07-02
4946 Mechanical evolution of metastatic cancer cells in three-dimensional microenvironment
Hilai, K.; Grubich, D.; Akrawi, M.; Zhu, H.; Zaghloul, R.; Shi, C.; Do, M.; Zhu, D.; Zhang, J.
10.1101/2024.06.27.601015 — biophysics — Posted on 2024-07-02
4952 Wound closure after brain injury relies on force generation by microglia in zebrafish
El-Daher, F.; Drake, L. K.; Enos, S. J.; Wehner, D.; Westphal, M.; Porter, N. J.; Becker, C. G.; Becker, T.
10.1101/2024.06.04.597300 — neuroscience — Posted on 2024-07-02
4953 Mechano-regulation of GLP-1 production by Piezo1 in intestinal L cells
Huang, Y.; Mo, H.; Yang, J.; Gao, L.; Tao, T.; Shu, Q.; Guo, W.; Zhao, Y.; Lyu, J.; Wang, Q.; Guo, J.; Zhai, H.; Zhu, L.; Chen, H.; Xu, G.
10.1101/2024.04.01.587569 — physiology — Posted on 2024-07-02
4954 Approaching Maximum Resolution in Structured Illumination Microscopy via Accurate Noise Modeling
Saurabh, A.; Brown, P. T.; Bryan, J. S.; Fox, Z. R.; Kruithoff, R.; Thompson, C.; Kural, C.; Shepherd, D. P.; Presse, S. P.
10.1101/2023.12.07.570701 — biophysics — Posted on 2024-07-02
4955 Castanet: a pipeline for rapid analysis of targeted multi-pathogen genomic data
Mayne, R. M.; Secret, S.; Geoghegan, C.; Trebes, A.; Kean, K.; Reid, K.; Lin, G.-L.; Ansari, M. A.; de Cesare, M.; Bonsall, D.; Elliott, I.; Piazza, P.; Brown, A.; Bray, J.; Knight, J. C.; Harvala, H.; Breuer, J.; Simmonds, P.; Bowden, R. J.; Golubchik, T.
10.1101/2024.06.28.601013 — bioinformatics — Posted on 2024-07-02
4956 plasma: Partial LeAst Squares for Multiomics Analysis
Yamaguchi, K.; Abdelbaky, S.; Yu, L.; Oakes, C. C.; Abruzzo, L. V.; Coombes, K. R.
10.1101/2023.03.10.532096 — bioinformatics — Posted on 2024-07-02
4957 Hydrogels for Local and Sustained Delivery of Bacteriophages to Treat Wound Infections
Lin, Y.-H.; Dharmaraj, T.; Chen, Q.; Echterhof, A.; Manasherob, R.; Zheng, L. J.; de Leeuw, C.; Peterson, N. A.; Stannard, W.; Li, Z.; Hajfathalian, M.; Hargil, A.; Martinez, H. A.; Chang, T. H. W.; Blankenberg, F. G.; Amanatullah, D.; Chaudhuri, O.; Bollyky, P. L.
10.1101/2024.05.07.593005 — bioengineering — Posted on 2024-07-02
4958 Enhanced binding of guanylated poly(A) RNA by the LaM domain of LARP1
Kozlov, G.; Jiang, J.; Rutherford, T.; Noronha, A.; Wilds, C.; Gehring, K.
10.1101/2024.05.08.593157 — biochemistry — Posted on 2024-07-02
4962 A direct experimental test of Ohno's hypothesis
Mihajlovic, L.; Iyengar, B. R.; Baier, F.; Barbier, I.; Iwaszkiewicz, J.; Zoete, V.; Wagner, A.; Schaerli, Y.
10.1101/2023.09.25.559237 — evolutionary biology — Posted on 2024-07-02
4963 Weighting of sensory cues reflect changing patterns of visual investment during ecological divergence in Heliconius butterflies.
Borrero, J.; Mogollon Perez, E. A.; Wright, D. S.; Lozano, D.; Rueda-Munoz, G.; Pardo-Diaz, C.; Salazar, C.; Montgomery, S. H.; Merrill, R. M.
10.1101/2024.04.03.587949 — evolutionary biology — Posted on 2024-07-02
4964 Scalable Hypothalamic Arcuate Neuron Differentiation from Human Pluripotent Stem Cells Suitable for Modeling Metabolic and Reproductive Disorders
Jovanovic, V. M.; Narisu, N.; Bonnycastle, L. L.; Tharakan, R.; Mesch, K. T.; Glover, H. J.; Yan, T.; Sinha, N.; Sen, C.; Castellano, D.; Yang, S.; Blivis, D.; Ryu, S.; Bennett, D. F.; Rosales-Soto, G.; Inman, J.; Ormanoglu, P.; LeClair, C. A.; Xia, M.; Schneider, M.; Hernandez-Ochoa, E. O.; Erdos, M. R.; Simeonov, A.; Chen, S.; Singec, I.; Collins, F. S.; Doege, C. S.; Tristan, C. A.
10.1101/2024.06.27.601062 — developmental biology — Posted on 2024-07-02
4965 A novel family of lncRNAs relate facioscapulohumeral muscular dystrophy to nucleolar architecture and protein synthesis
Salsi, V.; Losi, F.; Fosso, B.; Ferrarini, M.; Pini, S.; Manfredi, M.; Vattemi, G. N. A.; Mongini, T. E.; Maggi, L.; Pesole, G. D.; Henras, A.; Kaufman, P. D.; McStay, B.; Tupler, R. G.
10.1101/2024.06.29.600824 — molecular biology — Posted on 2024-07-02
4972 Ageing impacts basic auditory and timing processing
Criscuolo, A.; Schwartze, M.; Bonetti, L.; Kotz, S. A.
10.1101/2024.03.24.586049 — neuroscience — Posted on 2024-07-02
4973 Dopamine Dynamics Underlying Alloparental Behavioral Acquisition Facilitated by Top-down Orbitofrontal Inputs in Female Mice
Tasaka, G.-i.; Hagihara, M.; Irie, S.; Kobayashi, H.; Inada, K.; Kobayashi, K.; Kato, S.; Kobayashi, K.; Miyamichi, K.
10.1101/2023.02.03.527077 — neuroscience — Posted on 2024-07-02
4974 Control of innate olfactory valence by segregated cortical amygdala circuits
Howe, J. R.; Chan, C.-L.; Lee, D.; Blanquart, M.; Romero, H.; Zadina, A. N.; Lemieux, M. E.; Desplats, P. A.; Tye, K. M.; Root, C. M.
10.1101/2024.06.26.600895 — neuroscience — Posted on 2024-07-02
4976 Spike-phase coupling of subthalamic neurons to posterior opercular cortex predicts speech sound accuracy
Vissani, M.; Bush, A.; Lipski, W. J.; Bullock, L.; Fischer, P.; Neudorfer, C.; Holt, L. L.; Fiez, J. A.; Turner, R. S.; Richardson, R. M.
10.1101/2023.10.18.562969 — neuroscience — Posted on 2024-07-02
4977 Cellular and Molecular Changes During Aging in MEC: Unveiling the Role of Bglap3 Neurons in Cognitive Aging
Miao, C.; Cao, Q.; Uzeen, S.; Cheng, S.; Liu, Y.; Liu, J.; Wen, S.; Zhong, M.; Hao, J.; Yao, S.; Yang, Y.; Yan, X.; Guo, W.
10.1101/2024.06.27.600930 — neuroscience — Posted on 2024-07-02
4979 Scale matters: Large language models with billions (rather than millions) of parameters better match neural representations of natural language
Hong, Z.; Wang, K.; Zada, Z.; Gazula, H.; Turner, D.; Aubrey, B.; Niekerken, L.; Doyle, W.; Devore, S.; Dugan, P.; Friedman, D.; Devinsky, O.; Flinker, A.; Hasson, U.; Nastase, S.; Goldstein, A.
10.1101/2024.06.12.598513 — neuroscience — Posted on 2024-07-02
4980 Simulating 500 million years of evolution with a language model
Hayes, T.; Rao, R.; Akin, H.; Sofroniew, N. J.; Oktay, D.; Lin, Z.; Verkuil, R.; Tran, V. Q.; Deaton, J.; Wiggert, M.; Badkundri, R.; Shafkat, I.; Gong, J.; Derry, A.; Molina, R. S.; Thomas, N.; Khan, Y. A.; Mishra, C.; Kim, C.; Bartie, L. J.; Nemeth, M.; Hsu, P. D.; Sercu, T.; Candido, S.; Rives, A.
10.1101/2024.07.01.600583 — synthetic biology — Posted on 2024-07-02
4983 Acarbose ameliorates Western diet-induced metabolic and cognitive impairments in the 3xTg mouse model of Alzheimer's disease
Sonsalla, M. M.; Babygirija, R.; Johnson, M.; Cai, S.; Cole, M.; Yeh, C.-Y.; Grunow, I.; Liu, Y.; Vertein, D.; Calubag, M. F.; Trautman, M. E.; Green, C. L.; Rigby, M. J.; Puglielli, L.; Lamming, D. W.
10.1101/2024.06.27.600472 — physiology — Posted on 2024-07-02
4984 FKBP12-BOUND CALCINEURIN CONTROL TMEM16A ACTIVITY
Guzman-Hernandez, M. L.; Huerta, M.; Lopez-Romero, A. E.; Moran-Zendejas, R.; Betanzos, A.; Perez-Cornejo, P.; ARREOLA, J.
10.1101/2024.06.27.601078 — physiology — Posted on 2024-07-02
4985 SntB triggers the antioxidant pathways to regulate development and aflatoxin biosynthesis in Aspergillus flavus
Wu, D.; Yang, C.; Yao, Y.; Ma, D.; Lin, H.; Hao, L.; Xin, W.; Ye, K.; Sun, M.; Hu, Y.; Yang, Y.; Zhuang, Z.
10.1101/2023.12.19.572357 — pharmacology and toxicology — Posted on 2024-07-02
4986 The Ubiquitin Ligase RBX2/SAG Regulates Mitochondrial Ubiquitination and Mitophagy
Wang, W.; Li, E.; Zou, J.; Qu, C.; Ayala, J.; Wen, Y.; Islam, M. S.; Weintraub, N. L.; Fulton, D. J.; Liang, Q.; Zhou, J.; Liu, J.; Li, J.; Sun, Y.; Su, H.
10.1101/2024.02.24.581168 — pathology — Posted on 2024-07-02
4987 TEtrimmer: a novel tool to automate the manual curation of transposable elements
Qian, J.; Xue, H.; Ou, S.; Storer, J. M.; Fuertauer, L.; Wildermuth, M. C.; Kusch, S.; Panstruga, R.
10.1101/2024.06.27.600963 — bioinformatics — Posted on 2024-07-02
4988 A stabilized MERS-CoV spike ferritin nanoparticle vaccine elicits robust and protective neutralizing antibody responses
Powell, A. E.; Caruso, H.; Park, S.; Chen, J.-L.; O'Rear, J.; Ferrer, B. J.; Walker, A.; Bruening, A.; Hartwig, A.; Ahyong, V.; Dougherty, C. S.; Bowen, R. A.; Ledgerwood, J. E.; Kay, M. S.; Weidenbacher, P. A.- B.; Palanski, B. A.
10.1101/2024.07.01.601243 — biochemistry — Posted on 2024-07-02
4991 A High-quality Oxford Nanopore Assembly of the Hourglass Dolphin (Sagmatias cruciger) Genome
McGrath, N.; le Roux, J.; Whibley, A.; Alexander, A.; Stewart, R. O.; Johnstone, M.; Stockin, K. A.; Silander, O. K.
10.1101/2024.05.30.596754 — genomics — Posted on 2024-07-02
4993 AURA: Automated Universal RNAscope Analysis for high-throughput applications
Descarpentrie, J.; Bernard, F.; Souleyreau, W.; Brisson, L.; Mathivet, T.; Pateras, I. S.; Martin, O. C.; Frisan, T.
10.1101/2024.06.28.601140 — cell biology — Posted on 2024-07-02
4995 Comprehensive analysis of the microbial consortium in the culture of flagellate Monocercomonoides exilis
Jimenez-Gonzalez, A.; Treitli, S. C.; Pena-Diaz, P.; Janovska, A.; Benes, V.; Zacek, P.; Hampl, V.
10.1101/2024.02.02.578639 — microbiology — Posted on 2024-07-02
4996 CD28 Shapes T Cell Receptor Signaling by Regulating ZAP70 Activation and Lck Dynamics
Raychaudhuri, K.; Rangu, R.; Ma, A.; Alvinez, N.; Tran, A. D.; Pallikkuth, S.; McIntire, K. M.; Garvey, J. A.; Yi, J.; Samelson, L. E.
10.1101/2024.06.27.601067 — immunology — Posted on 2024-07-02
4997 Antigen specificity shapes antibody functions in tuberculosis.
Miles, J. R.; Lu, P.; Bai, S.; Aguillon-Duran, G.; Rodriguez-Herrera, J.; Gunn, B.; Restrepo, B.; Lu, L.
10.1101/2024.06.03.597169 — immunology — Posted on 2024-07-02
4998 An Atlas of Protein Phosphorylation Dynamics During Interferon Signaling
Busnadiego, I.; Lork, M.; Fernbach, S.; Schiefer, S.; Tsolakos, N.; Hale, B. G.
10.1101/2024.06.28.601147 — immunology — Posted on 2024-07-02
5000 Multiple mechanisms of aminoglycoside ototoxicity are distinguished by subcellular localization of action
Wu, P.; Becker, F. B.; Ogelman, R.; Camci, E.; Linbo, T. H.; Simon, J. A.; Rubel, E. W.; Raible, D.
10.1101/2024.05.30.596537 — neuroscience — Posted on 2024-07-02
5001 A central steering circuit in Drosophila
Feng, K.; Khan, M.; Minegishi, R.; Mueller, A.; Van De Poll, M. N.; Swinderen, B. v.; Dickson, B. J.
10.1101/2024.06.27.601106 — neuroscience — Posted on 2024-07-02
5002 Exploring anterior thalamus functional connectivity with cortical regions in prospective memory with ultra-high field fMRI
Flanagan, L.; Mansur, B. d. M.; Reichert, C.; Richter, A.; Golbabaei, S.; Kizilirmak, J. M.; Sweeney-Reed, C. M.
10.1101/2024.02.14.580346 — neuroscience — Posted on 2024-07-02
5003 Comprehensive evaluation of phosphoproteomic-based kinase activity inference
Mueller-Dott, S.; Jaehnig, E. J.; Munchic, K. P.; Jiang, W.; Yaron-Barir, T. M.; Savage, S. R.; Garrido-Rodriguez, M.; Johnson, J. L.; Lussana, A.; Petsalaki, E.; Lei, J. T.; Dugourd, A.; Krug, K.; Cantley, L. C.; Mani, D. R.; Zhang, B.; Saez-Rodriguez, J.
10.1101/2024.06.27.601117 — systems biology — Posted on 2024-07-02
5006 Hydroxysteroid 17-beta dehydrogenase 13 (Hsd17b13) knockdown attenuates liver steatosis in high-fat diet obese mice
Mahmood, S.; Morrice, N. Z.; Thompson, D.; Milanizadeh, S.; Wilson, S.; Whitfield, P. D.; Mcilroy, G. D.; Rochford, J. J.; Mody, N.
10.1101/2024.02.27.582262 — physiology — Posted on 2024-07-02
5008 Atypical contribution of caspase-3 to melanoma cancer cell motility by regulation of coronin 1B activity
Berthenet, K.; Diazzi, S.; Jamard, C.; Stopa, K.; Dragan, S.; Fanfone, D.; Nguyen, T.; Al, N.; Virard, F.; Meurette, O.; Popgeorgiev, N.; Hernandez-Vargas, H.; Ablain, J.; Ichim, G.
10.1101/2024.06.27.601010 — cancer biology — Posted on 2024-07-02
5009 The TissueTractor, a device for applying large strains to tissues and cells for simultaneous high-resolution live cell microscopy.
Yang, J.; Hearty, E.; Wang, Y.; Vijayraghavan, D. S.; Walter, T.; Anjum, S.; Stuckenholz, C.; Cheng, Y.-W.; Balasubramanian, S.; Kwiatkowski, A. V.; Davidson, L. A.
10.1101/2024.06.28.600827 — biophysics — Posted on 2024-07-02
5010 Real-time visualization reveals Mycobacterium tuberculosis ESAT-6 disrupts phagosome via fibril-mediated vesiculation
Koiri, D.; Nandi, M.; PM, A. H.; Bhausaheb, A. J.; Meher, G.; Behura, A.; Kumar, A.; Choudhary, V.; Choubey, S.; Saleem, M.
10.1101/2024.04.19.590309 — biophysics — Posted on 2024-07-02
5014 Effects of microplastics on Daphnia-associated microbiomes in situ and in vitro
Krzynowek, A.; Van de Moortel, B.; Pichler, N.; Vanoverberghe, I.; Lapere, J.; Jenisch, L.; Deloof, D.; Thielemans, W.; Muylaert, K.; Dusselier, M.; Springael, D.; Faust, K.; Decaestecker, E.
10.1101/2024.06.28.601137 — ecology — Posted on 2024-07-02
5015 Enteric Populations of Escherichia coli are Likely to be Resistant to Phages Due to O Antigen Production
Berryhill, B. A.; Burke, K. B.; Fontaine, J.; Brink, C. E.; Harvill, M. G.; Goldberg, D. A.; Konstantinidis, K. T.; Levin, B. R.; Woodworth, M. H.
10.1101/2023.11.08.566299 — microbiology — Posted on 2024-07-02
5017 Dissociation between biomechanical stiffness and sEMG activity in trapezius and lumbar skeletal muscles in steady postures
Veraksits, A.; Reinvee, M.; Ereline, J.; Gapeyeva, H.; Kums, T.; Gavronski, G.; Paasuke, M.; Vasar, E.
10.1101/2024.06.27.600991 — biophysics — Posted on 2024-07-02
5019 Reduced Auditory Perception and Brain Response with Quiet TMS Coil
Murphy, D. L. K.; Koponen, L. M.; Wood, E.; Li, Y.; Bukhari-Parlakturk, N.; Goetz, S. M.; Peterchev, A. V.
10.1101/2024.06.24.600400 — bioengineering — Posted on 2024-07-02
5020 An Autonomous Implantable Device for the Prevention of Death from Opioid Overdose
Ciatti, J. L.; Vazquez-Guardado, A.; Brings, V. E.; Park, J.; Ruyle, B.; Ober, R. A.; McLuckie, A. J.; Talcott, M. R.; Carter, E. A.; Burrell, A. R.; Sponenburg, R. A.; Trueb, J.; Gupta, P.; Kim, J.; Avila, R.; Seong, M.; Slivicki, R. A.; Kaplan, M. A.; Villalpando, B.; Massaly, N.; Montana, M. C.; Pet, M.; Huang, Y.; Moron, J. A.; Gereau, R. W.; Rogers, J. A.
10.1101/2024.06.27.600919 — bioengineering — Posted on 2024-07-02
5021 Evolutionarily conserved principles of ESCRT-III-mediated membrane remodelling revealed by a two-subunit Asgard archaeal system
Souza, D. P.; Espadas, J.; Chaaban, S.; Moody, E. R. R.; Hatano, T.; Balasubramanian, M.; Williams, T. A.; Roux, A.; Baum, B.
10.1101/2024.07.01.601590 — evolutionary biology — Posted on 2024-07-02
5022 Temporal stability of sex ratio distorter prevalence in natural populations of the isopod Armadillidium vulgare
Durand, S.; Pigeault, R.; Giraud, I.; Loisier, A.; Bech, N.; Grandjean, F.; Rigaud, T.; Peccoud, J.; Cordaux, R.
10.1101/2023.11.27.568845 — evolutionary biology — Posted on 2024-07-02
5024 Novel Mechanism for Tubular Injury in Nephropathic Cystinosis
Sur, S.; Kerwin, M.; Pineda, S.; Sansanwal, P.; Sigdel, T. K.; Sirota, M.; Sarwal, M. M.
10.1101/2022.05.13.491826 — cell biology — Posted on 2024-07-02
5025 Induction of neutralising antibodies against conserved rhinovirus capsid protein VP4 depends on presenting VP4 in a virus-like conformation
Kelly, J. T.; Dellosa, G. K.; Newman, J.; Hills, R.; Mohamed, A. A. M.; Aniscenko, J.; Johnston, S. L.; Tuthill, T. J.
10.1101/2024.06.28.601138 — microbiology — Posted on 2024-07-02
5028 Synthesis of alkyl glucosides catalyzed by immobilized α-amylase from Thermotoga maritima
Xolalpa-Villanueva, W.; Ramirez-Amador, F. O.; Olvera, L.; Miranda-Molina, A.; Lopez-Munguia, A.; Saab-Rincon, G.
10.1101/2024.06.28.601278 — biochemistry — Posted on 2024-07-02
5029 Glycation of alpha-synuclein enhances aggregation and neuroinflammatory responses
Vasili, E.; Konig, A.; Al-Azzani, M.; Bosbach, C.; Gatzemeier, L. M.; Chegao, A.; Miranda, H. V.; Erskine, D.; Outeiro, T.
10.1101/2024.06.27.600956 — neuroscience — Posted on 2024-07-02
5032 TEtrimmer: a novel tool to automate the manual curation of transposable elements
QIAN, J.; Xue, H.; Ou, S.; Storer, J. M.; Fuertauer, L.; Wildermuth, M. C.; Kusch, S.; Panstruga, R.
10.1101/2024.06.27.600963 — bioinformatics — Posted on 2024-07-02
5034 Interhemispheric Connectivity of the Human Temporal Lobes
Binder, J. R.; Giraldo-Chica, M.; Mathis, J.; Tong, J.-Q.; Schoenrock, S.; Arpinar, V.; Muftuler, L. T.
10.1101/2024.07.01.601568 — neuroscience — Posted on 2024-07-01
5035 Deep genetic substructure within bonobos
Han, S.; de Filippo, C.; Parra, G.; Meneu, J. R.; Laurent, R.; Frandsen, P.; Hvilsom, C.; Gronau, I.; Marques-Bonet, T.; Kuhlwilm, M.; Andres, A. M.
10.1101/2024.07.01.601523 — evolutionary biology — Posted on 2024-07-01
5038 Phage display profiling of CDR3β loops enables machine learning predictions of NY-ESO-1 specific TCRs
Croce, G.; Lani, R.; Tardivon, D.; Bobisse, S.; de Tiani, M.; Bragina, M.; Perez, M. A.; Schmidt, J.; Guillame, P.; Zoete, V.; Harari, A.; Rufer, N.; Hebeisen, M.; Dunn, S.; Gfeller, D.
10.1101/2024.06.27.600973 — bioinformatics — Posted on 2024-07-01
5039 Leveraging Basecaller's Move Table to Generate a Lightweight k-mer Model
Samarakoon, H.; Kei Wan, Y.; Parameswaran, S.; Göke, J.; Gamaarachchi, H.; Deveson, I. W.
10.1101/2024.06.30.601452 — bioinformatics — Posted on 2024-07-01
5042 Efficient Generation of SOCS2 Knock-out Sheep by Electroporation of CRISPR-Cas9 Ribonucleoprotein Complex with Dual-sgRNAs.
Mahdi, A. K.; Fitzpatrick, D. S.; Hagen, D. E.; McNabb, B. R.; Urbano, T.; Muir, W. M.; Werry, N.; Van Eenennaam, A. L.; Medrano, J. F.; ROSS, P. J.
10.1101/2024.06.30.601433 — bioengineering — Posted on 2024-07-01
5043 Large-Scale Comparative Transcriptomic Analysis of CHO Cell Functional Adaptation to Recombinant Monoclonal Antibody Production
Alexandru-Crivac, C. N.; Cartwright, J. F.; Taylor, R. M.; Sweeney, B. M.; Feary, M.; Chathoth, K. T.; Fabian, D. K.; Allsopp, H.; Brown, A. J.; James, D. C.
10.1101/2024.06.27.600995 — bioengineering — Posted on 2024-07-01
5044 Down regulation of Engase in Caenorhabditis elegans may improve its stresses adaptivity
Lu, X.; Tong, Y.; Wu, M.; Lyu, S.; Fan, J.; Zheng, J.; Zou, L.; Shen, D.; Rao, L.; Hou, L.; Chen, C.; Cheng, X.; Sun, G.; Shao, Z.; Chen, L.
10.1101/2024.07.01.601486 — biochemistry — Posted on 2024-07-01
5045 A stabilized MERS-CoV spike ferritin nanoparticle vaccine elicits robust and protective neutralizing antibody responses
Powell, A. E.; Caruso, H.; Park, S.; Chen, J.-L.; O'Rear, J.; Ferrer, B. J.; Walker, A.; Bruenig, A.; Hartwig, A.; Ahyong, V.; Dougherty, C. S.; Bowen, R. A.; Ledgerwood, J. E.; Kay, M. S.; Weidenbacher, P. A.- B.; Palanski, B. A.
10.1101/2024.07.01.601243 — biochemistry — Posted on 2024-07-01
5046 Streamlined screening platforms lead to the discovery of pachysiphine synthase from Tabernanthe iboga
Kamileen, M. O.; Nakamura, Y.; Luck, K.; Heinicke, S.; Hong, B.; Colinas, M.; Lichman, B. R.; O'Connor, S. E.
10.1101/2024.06.30.601415 — biochemistry — Posted on 2024-07-01
5047 Inhibition of serine racemase prevents diabetic retinopathy
Jiang, H.; Zhou, P.; Jiang, X.; wu, X.; Mao, Y.; Liu, S.; Tang, S.; Zhou, J.; Zhang, Z.; Ren, B.; Shan, G.; Qu, J.; Wu, S.
10.1101/2024.06.30.601441 — biochemistry — Posted on 2024-07-01
5048 Multi-sample non-negative spatial factorization
Wang, Y.; Woyshner, K.; Sriworarat, C.; Stein-O'Brien, G.; Goff, L. A.; Hansen, K. D.
10.1101/2024.07.01.599554 — genomics — Posted on 2024-07-01
5049 The Amphibian Genomics Consortium: advancing genomic and genetic resources for amphibian research and conservation
Kosch, T. A.; Torres-Sanchez, M.; Liedtke, H. C.; Summers, K.; Yun, M. H.; Crawford, A. J.; Maddock, S. T.; Ahammed, M. S.; Araujo, V. L. N.; Vincenzo Bertola, L.; Bucciarelli, G.; Carne, A.; Carneiro, C. M.; Chan, K. O.; Chen, Y.; Crottini, A.; da Silva, J. M.; Denton, R. D.; Dittrich, C.; Espregueira Themudo, G.; Farquharson, K. A.; Forsdick, N. J.; Gilbert, E.; Che, J.; Katzenback, B. A.; Kotharambath, R.; Levis, N. A.; Marquez, R.; Mazepa, G.; Mulder, K. P.; Muller, H.; O'Connell, M. J.; Orozco-terWengel, P.; Palomar, G.; Petzold, A.; Pfennig, D. W.; Pfennig, K. S.; Reichert, M. S.; Robert
10.1101/2024.06.27.601086 — genomics — Posted on 2024-07-01
5051 Muskelin acts as a substrate receptor of the highly regulated Drosophila CTLH E3 ligase during the maternal-to-zygotic transition
Briney, C. A.; Henriksen, J. C.; Lin, C.; Jones, L. A.; Benner, L.; Rains, A. B.; Gutierrez, R.; Gafken, P. R.; Rissland, O.
10.1101/2024.06.28.601265 — developmental biology — Posted on 2024-07-01
5052 Identification of mCMQ069, a novel antimalarial with potential for a single-dose cure and/or 28-day chemoprevention
Gupta, A. K.; Pedroarena, J.; Nazarian, A.; Antonova-Koch, J.; Weiss, F.; Kumpornsin, K.; Chi, V.; Woods, A. K.; Lee, K.-J.; Joseph, S. B.; Li, S.; Brittain, J.; Hostos, E. D.; Duffy, J.; Cooper, A.; Schultz, P. G.; McNamara, C. W.; Chatterjee, A. K.
10.1101/2024.07.01.601566 — microbiology — Posted on 2024-07-01
5053 Human erythroid progenitors express antigen presentation machinery
Clements, R. L.; Kennedy, E. A.; Song, D.; Campbell, A.; An, H. H.; Amses, K. R.; Miller-Ensminger, T.; Addison, M. M.; Eisenlohr, L. C.; Chou, S. T.; Jurado, K. A.
10.1101/2024.06.27.601047 — immunology — Posted on 2024-07-01
5054 Distinct neutrophil effector functions in response to different isolates of Leishmania aethiopica
Adem, E.; Cruz Cervera, E.; Yizengaw, E.; Takele, Y.; Shorter, S.; Cotton, J.; Getti, G.; Kropf, P.
10.1101/2024.06.27.601019 — immunology — Posted on 2024-07-01
5055 Sulfur Amino Acid Restriction Enhances Exercise Capacity in Mice by Boosting Fat Oxidation
Mann, C. G.; MacArthur, M. R.; Zhang, J.; Gong, S.; AbuSalim, J. E.; Hunter, C. J.; Lu, W.; Agius, T.; Longchamp, A.; Allagnat, F.; Rabinowitz, J.; Mitchell, J. R.; De Bock, K.; Mitchell, S. J.
10.1101/2024.06.27.601041 — physiology — Posted on 2024-07-01
5058 In Vitro Generation and Characterization of The Wu Syndrome Model That Causes Mental Retardation in Neural Cell Lines
Karaman, S. S.; Sevik, T.; Akdemir, S.; Bilgin, B.; Karadeli, E.; Yalcin, D.; Baran, B.; Gelsin, B.; Budaklar, B.; Sert, B.; Gulden, G.; Tastan, C.
10.1101/2024.07.01.601494 — molecular biology — Posted on 2024-07-01
5059 Gene body methylation buffers noise in gene expression in plants
Zastapilo, J.; Emmerson, R. A.; Mikheeva, L. A.; Catoni, M.; Bechtold, U.; Zabet, N. R.
10.1101/2024.07.01.601483 — molecular biology — Posted on 2024-07-01
5060 MeCP2 Interacts with the Super Elongation Complex to Regulate Transcription
Sonn, J. Y.; Kim, W.; Iwanaszko, M.; Aoi, Y.; Li, Y.; Parkitny, L.; Brissette, J. L.; Weiner, L.; Al-Ramahi, I.; Botas, J.; Shilatifard, A.; Zoghbi, H. Y.
10.1101/2024.06.30.601446 — molecular biology — Posted on 2024-07-01
5063 Beta-1,6-glucan plays a central role in the structure and remodeling of the bilaminate fungal cell wall
Bekirian, C.; Valsecchi, I.; Bachellier-Bassi, S.; Scandola, C.; Guijarro, J. I.; Chauvel, M.; Mourer, T.; Gow, N.; Aimanianda Bopaiah, V. K.; d'Enfert, C.; Fontaine, T.
10.1101/2024.06.30.601427 — microbiology — Posted on 2024-07-01
5064 Rational Design of Frontline Institutional Phage Cocktail for the Treatment of Nosocomial Enterobacter cloacae Complex Infections
Subedi, D.; Gordillo Altamirano, F. L.; Deehan, R.; Perera, A.; Patwa, R.; Kostoulias, X.; Korneev, D.; Blakeway, L.; Wiesnewski, J.; Macesic, N.; Peleg, A. Y. L.; Barr, J. J.
10.1101/2024.06.30.601436 — microbiology — Posted on 2024-07-01
5068 Differential action modes of Neutrophil Extracellular Trap-targeted drugs define T cell responses in SARS-CoV-2 infection.
Bonilha, C. S.; Veras, F. P.; Ramos, A. d. S.; Gomes, G. F.; Lemes, R. M. R.; Arruda, E.; Alves-Filho, J. C.; Cunha, T. M.; Cunha, F. d. Q.
10.1101/2024.06.30.601403 — immunology — Posted on 2024-07-01
5069 Assessing the predictive value of peak alpha frequency for the sensitivity to pain
May, E. S.; Tiemann, L.; Gil Avila, C. S.; Bott, F. S.; Hohn, V.; Gross, J.; Ploner, M.
10.1101/2024.06.27.600974 — neuroscience — Posted on 2024-07-01
5071 Dual roles of idling moments in past and future memories
Inokuchi, K.; Ghandour, K.; Haga, T.; Ohkawa, N.; FUNG, C. C. A.; Nomoto, M.; Fayed, M. R.; Asai, H.; Sato, M.; Fukai, T.
10.1101/2024.06.27.600961 — neuroscience — Posted on 2024-07-01
5074 PRDM16-DT is a Brain and Astrocyte-Specific lncRNA Implicated in Alzheimers Disease
Schroeder, S.; Fuchs, U.; GIsa, V.; Pena, T.; Krueger, D. M.; Hempel, N.; Burkhardt, S.; Salinas-Riester, G.; Schuetz, A.-L.; Delalle, I.; Sananbenesi, F.; Fischer, A.
10.1101/2024.06.27.600964 — neuroscience — Posted on 2024-07-01
5075 Mitochondrial maintenance is involved in the exceptional longevity of reproductive queens of the eusocial ant Lasius niger
Kervella, M.; Bertile, F.; Granger-Farbos, A.; Pinson, B.; Schmitt, A.; Quque, M.; Bouillaud, F.; Criscuolo, F.
10.1101/2024.06.27.600950 — physiology — Posted on 2024-07-01
5077 Hydrogels for Local and Sustained Delivery of Bacteriophages to Treat Wound Infections
Lin, Y.-H.; Dharmaraj, T.; Chen, Q.; Echterhof, A.; Manasherob, R.; Zheng, L. J.; de Leeuw, C.; Peterson, N. A.; Stannard, W.; Li, Z.; Hajfathalian, M.; Hargil, A.; Martinez, H. A.; Chang, T. H. W.; Blankenberg, F. G.; Amanatullah, D.; Chaudhuri, O.; Bollyky, P. L.
10.1101/2024.05.07.593005 — bioengineering — Posted on 2024-07-01
5078 Extended-depth of field random illumination microscopy, EDF-RIM, provides super-resolved projective imaging
Mazzella, l.; Mangeat, T.; Giroussens, G.; Rogez, B.; Li, H.; Creff, J.; Saadaoui, m.; Martins, C.; Labouesse, S.; Idier, J.; Galland, F.; Allain, M.; Sentenac, A.; LeGoff, L.
10.1101/2023.10.30.564754 — bioengineering — Posted on 2024-07-01
5079 Compromising tyrosine hydroxylase function establishes a delusion-like temporal profile of reinforcement by dopamine neurons in Drosophila
Amin, F.; Koenig, C.; Zhang, J.; Kalinichenko, L. S.; Koenigsmann, S.; Brunsberg, V.; Riemensperger, T. D.; Mueller, C. P.; Gerber, B.
10.1101/2024.06.27.600982 — animal behavior and cognition — Posted on 2024-07-01
5080 Genomic Evidence of Fisheries Induced Evolution in Eastern Baltic cod
Han, K. Y.; Brennan, R. S.; Monk, C. T.; Jentoft, S.; Helmerson, C.; Dierking, J.; Huessy, K.; Kokubun, E. E.; Fuss, J.; Krause-Kyora, B.; Thomsen, T. B.; Heredia, B. D.; Reusch, T. B. H.
10.1101/2024.06.27.601002 — evolutionary biology — Posted on 2024-07-01
5083 Crk mediates Csk-Hippo signaling independently of Yap tyrosine phosphorylation to induce cell extrusion
Hannan, A.; Wang, Q.; Wu, Y.; Makrides, N.; Qu, X.; Mao, J.; Que, J.; Cardoso, W. V.; Zhang, X.
10.1101/2024.06.27.601065 — developmental biology — Posted on 2024-07-01
5084 Burst-dependent Thalamocortical Dynamics Underlie Perceptual Awareness
Whyte, C. J.; Munn, B. R.; Aru, J.; Larkum, M.; John, Y.; Muller, E. J.; Shine, J. M.
10.1101/2023.07.13.548934 — neuroscience — Posted on 2024-07-01
5085 Multiple mechanisms of aminoglycoside ototoxicity are distinguished by subcellular localization of action
Wu, P.; Becker, F. B.; Ogelman, R.; Camci, E.; Linbo, T. H.; Simon, J. A.; Rubel, E. W.; Raible, D.
10.1101/2024.05.30.596537 — neuroscience — Posted on 2024-07-01
5086 Functional lung imaging identifies peripheral ventilation changes in mice with muco-obstructive lung disease
Reyne, N.; Smith, R.; Cmielewski, P.; Eikelis, N.; Nilsen, K.; Louise, J.; Duerr, J.; Mall, M. A.; Lawrence, M.; Parsons, D.; Donnelley, M.
10.1101/2024.06.27.600946 — physiology — Posted on 2024-07-01
5088 PIKfyve controls dendritic cell function and tumor immunity
Choi, J. E.; Qiao, Y.; Kryczek, I.; Yu, J.; Gurkan, J.; Bao, Y.; Gondal, M.; Tien, J. C.-Y.; Maj, T.; Yazdani, S.; Parolia, A.; Xia, H.; Zhou, J.; Wei, S.; Grove, S.; Vatan, L.; Lin, H.; Li, G.; Zheng, Y.; Zhang, Y.; Cao, X.; Su, F.; Wang, R.; He, T.; Cieslik, M.; Green, M. D.; Zou, W.; Chinnaiyan, A. M.
10.1101/2024.02.28.582543 — cancer biology — Posted on 2024-07-01
5089 Latent mitotic vulnerability of AML cells induced by therapeutic agents
Niikura, R.; Yabushita, T.; Yamamoto, S.; Suzuki, H.; Fukuyama, M.; Hata, S.; Goyama, S.; Kitamura, T.; Chinen, T.; Kitagawa, D.
10.1101/2024.06.27.600939 — cancer biology — Posted on 2024-07-01
5090 RBM7 deficiency promotes breast cancer metastasis by coordinating MFGE8 splicing switch and NF-kB pathway
Huang, F.; Dai, Z.; Yu, J.; Wang, K.; Chen, C.; Chen, D.; Zhang, J.; Zhao, J.; Zhang, W.; Qi, Y.; Wang, Y.; Li, X.; Li, M.
10.1101/2024.01.03.574004 — cancer biology — Posted on 2024-07-01
5097 Polyphyletic domestication and inter-lineage hybridization magnified genetic diversity of cultivated melon, Cucumis melo L.
TANAKA, K.; Shigita, G.; Dung, T. P.; Nhi, P. T. P.; Takahashi, M.; Monden, Y.; Nishida, H.; Ishikawa, R.; Kato, K.
10.1101/2024.06.27.601017 — evolutionary biology — Posted on 2024-07-01
5098 Flexible movement kernel estimation in habitat selection analyses with generalized additive models
Arce Guillen, R.; Pohle, J.; Jeltsch, F.; Roeleke, M.; Reineking, B.; Klappstein, N.; Schlägel, U.
10.1101/2024.06.27.600970 — ecology — Posted on 2024-07-01
5100 Ecologically and economically sustainable level of timber harvesting in boreal forests - defining the safe operating space for forest use
Mönkkönen, M.; Blattert, C.; Cours, J.; Duflot, R.; Elo, M.; Eyvindson, K.; Kouki, J.; Trivino, M.; Burgas, D.
10.1101/2024.06.27.600997 — ecology — Posted on 2024-07-01
5101 Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival
Goswami, M. T.; Weh, E.; Subramanya, S.; Weh, K. M.; Durumutla, H. B.; Hager, H.; Miller, N.; Chaudhury, S.; Andren, A.; Sajjakulnukit, P.; Zhang, L.; Besirli, C. G.; Lyssiotis, C. A.; Wubben, T. J.
10.1101/2024.03.26.582525 — cell biology — Posted on 2024-07-01
5105 How predictability and individual alpha frequency shape memory: insights from the N400
Jano, S. L.; Chatburn, A.; Cross, Z. R.; Schlesewsky, M.; Bornkessel-Schlesewsky, I.
10.1101/2023.10.25.564081 — neuroscience — Posted on 2024-07-01
5108 APOE, Immune Factors, Sex, and Diet Interact to Shape Brain Networks in Mouse Models of Aging
Winter, S.; Mahzarnia, A.; Anderson, R. J.; Han, Z. Y.; Tremblay, J. J.; Stout, J. A.; Moon, H. S.; Marcellino, D.; Dunson, D.; Badea, A.
10.1101/2023.10.04.560954 — neuroscience — Posted on 2024-07-01
5111 Cytokinin-inducible DIRIGENT13 involved in lignan synthesis and ROS accumulation promotes root growth and abiotic stress tolerance in Arabidopsis
Melnikava, A.; Perreau, F.; Paniagua, C.; Cheng, S.-C.; Huang, L.-M.; Ubogoeva, E.; Zemlyanskaya, E.; Yang, Y.-L.; Mouille, G.; Arnaud, D.; Hejatko, J.
10.1101/2024.06.25.600713 — plant biology — Posted on 2024-07-01
5112 Alasemenia, the earliest ovule with three wings and without cupule
Wang, D.; Yang, J.; Liu, L.; Zhou, Y.; Xu, P.; Qin, M.; Huang, P.
10.1101/2023.10.11.561822 — paleontology — Posted on 2024-07-01
5117 Links between behaviour and resistances to acute hyperthermia and hypoxia using rainbow trout isogenic lines
Lagarde, H.; LALLIAS, D.; Phocas, F.; Goardon, L.; Bideau, M.; Guyvarc'h, F.; Labbe, L.; Dupont-Nivet, M.; Cousin, X.
10.1101/2023.10.19.563047 — animal behavior and cognition — Posted on 2024-07-01
5118 Single-cell analysis of human diversity in circulating immune cells
Kock, K. H.; Tan, L. M.; Han, K. Y.; Ando, Y.; Jevapatarakul, D.; Chatterjee, A.; Lin, Q. X. X.; Buyamin, E. V.; Sonthalia, R.; Rajagopalan, D.; Tomofuji, Y.; Sankaran, S.; Park, M.-S.; Abe, M.; Chantaraamporn, J.; Furukawa, S.; Ghosh, S.; Inoue, G.; Kojima, M.; Kouno, T.; Lim, J.; Myouzen, K.; Nguantad, S.; Oh, J.-M.; Rayan, N. A.; Sarkar, S.; Suzuki, A.; Thungsatianpun, N.; Venkatesh, P. N.; Moody, J.; Nakano, M.; Chen, Z.; Tian, C.; Zhang, Y.; Tong, Y.; Tan, C. T. Y.; Tizazu, A. M.; SG10K_Health Consortium, ; Loh, M.; Hwang, Y. Y.; Ho, R. C.; Larbi, A.; Ng, T. P.; Won, H.-H.; Wright, F. A.
10.1101/2024.06.30.601119 — genomics — Posted on 2024-07-01
5120 The Molecules Gateway: a homogeneous, searchable database of 150k annotated molecules from Actinomycetes
Simone, M.; Iorio, M.; Monciardini, P.; Santini, M.; Cantu, N.; Tocchetti, A.; Serina, S.; Brunati, C.; Vernay, T.; Gentile, A.; Aracne, M.; Cozzi, M.; van der Hooft, J.; Sosio, M.; Donadio, S.; Maffioli, S. I.
10.1101/2024.06.28.601135 — microbiology — Posted on 2024-07-01
5124 Cancer vaccine attenuates carcinogen induced head and neck cancer with impaired early T cell response
Kono, M.; Rokugo, M.; Quadarella, J. D.; Saito, S.; Komatsuda, H.; Fu, C.; Woo, S.-B.; Egloff, A. M.; Uppaluri, R.
10.1101/2024.06.26.600828 — cancer biology — Posted on 2024-07-01
5126 Novel Mechanism for Tubular Injury in Nephropathic Cystinosis
Sur, S.; Kerwin, M.; Pineda, S.; Sansanwal, P.; Sigdel, T. K.; Sirota, M.; Sarwal, M. M.
10.1101/2022.05.13.491826 — cell biology — Posted on 2024-07-01
5127 Evidence for a role of human blood-borne factors in mediating age-associated changes in molecular circadian rhythms
Schwarz, J. E.; Mrcela, A.; Lahens, N. F.; Li, Y.; Hsu, C.; Grant, G.; Skarke, C.; Zhang, S. L.; Sehgal, A.
10.1101/2023.04.19.537477 — molecular biology — Posted on 2024-07-01
5128 The sulfur-related metabolic status of Aspergillus fumigatus during infection reveals cytosolic serine hydroxymethyltransferase as a promising antifungal target.
Alharthi, R.; Sueiro-Olivares, M.; Storer, I.; Alshammri, H.; Scott, J.; Al-Shidhani, R.; Fortune-Grant, R.; Bignell, E.; Tabernero, L.; Bromley, M.; Zhao, C.; Amich, J.
10.1101/2024.03.08.582945 — microbiology — Posted on 2024-07-01
5133 PAN deadenylase ensures proper mitosis under conditions of microtubule stress by regulating spindle integrity and promoting cell survival
Verma, J.; He, Z.; Brown, J. A. R.; Dean, P.; Young, B.; Flibotte, S.; Howe, L. J.; Maxwell, C.; Roskelley, C.; Loewen, C.
10.1101/2024.05.01.591760 — cell biology — Posted on 2024-07-01
5134 A protective and broadly binding antibody class engages the influenza virus hemagglutinin head at its stem interface
Simmons, H. C.; Finney, J.; Kotaki, R.; Adachi, Y.; Moseman, A. P.; Watanabe, A.; Song, S.; Robinson-McCarthy, L. R.; Le Sage, V.; Kuraoka, M.; Moseman, E. A.; Kelsoe, G.; Takahashi, Y.; McCarthy, K. R.
10.1101/2023.12.13.571543 — microbiology — Posted on 2024-07-01
5137 The Role of Cilia in the Development, Survival, and Regeneration of Hair Cells
Boldizar, H.; Friedman, A.; Stanley, T.; Padilla, M.; Galdieri, J.; Sclar, A.; Stawicki, T. M.
10.1101/2024.04.01.587636 — neuroscience — Posted on 2024-07-01
5139 A Markovian neural barcode representing mesoscale cortical spatiotemporal dynamics.
Culp, J. M.; Ashby, D. M.; George, A.; Teskey, G. C.; Nicola, W.; McGirr, A.
10.1101/2024.06.29.601346 — neuroscience — Posted on 2024-07-01
5142 Human Accelerated Regions regulate gene networks implicated in apical-to-basal neural progenitor fate transitions
Noble, M. A.; Ji, Y.; Yim, K. M.; Yang, J. W.; Morales, M.; Abu-Shamma, R.; Pal, A.; Poulsen, R.; Baumgartner, M.; Noonan, J. P.
10.1101/2024.06.30.601407 — neuroscience — Posted on 2024-07-01
5148 Intestine-on-chip enhances nutrient and drug metabolism and maturation of iPSC-derived intestinal epithelial cells relative to organoids and Transwells
Moerkens, R.; Mooiweer, J.; Smits, E.; Berg, M.; Ramirez Sanchez, A. D.; Modderman, R.; Puschhof, J.; Pleguezuelos-Manzano, C.; Barrett, R. J.; Wijmenga, C.; Jonkers, I. H.; Withoff, S.
10.1101/2024.06.30.601390 — cell biology — Posted on 2024-07-01
5149 Membrane Curvature Promotes ER-PM Contact Formation via Junctophilin-EHD Interactions
Yang, Y.; Valencia, L. A.; Lu, C.-H.; Nakamoto, M. L.; Tsai, C.-T.; Liu, C.; Yang, H.; Zhang, W.; Jahed, Z.; Lee, W.-R.; Santoro, F.; Liou, J.; Wu, J. C.; Cui, B.
10.1101/2024.06.29.601287 — cell biology — Posted on 2024-07-01
5152 Allosteric modulation of protein kinase A in individuals affected by NLPD-PKA , a neurodegenerative disease in which the RIβ-L50R variant is expressed
Benjamin-Zukerman, T.; Pane, V.; Safadi-Safa, R.; Solomon, M.; Lev-Ram, V.; Aboraya, M.; Dakwar, A.; Bertinetti, D.; Hoy, A.; Mol, M.; van Swieten, J.; Herberg, F. W.; Maillard, R.; Ilouz, R.
10.1101/2024.06.30.601371 — cell biology — Posted on 2024-07-01