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Archive, 2020-05

4 Microbe-metabolite associations linked to the rebounding murine gut microbiome post-colonization with vancomycin resistant Enterococcus faecium
Mu, A.; Carter, G. P.; Li, L.; Isles, N. S.; Vrbanac, A. F.; Morton, J. T.; Jarmusch, A. K.; De Souza, D. P.; Narayana, V. K.; Kanojia, K.; Nijagal, B.; McConville, M. J.; Knight, R.; Howden, B. P.; Stinear, T. P.
10.1101/849539 — microbiology — Posted on 2020-05-31
5 The carboxyl-termini of RAN translated GGGGCC nucleotide repeat expansions modulate toxicity in models of ALS/FTD
He, F.; Flores, B. N.; Krans, A.; Frazer, M.; Natla, S.; Niraula, S.; Adefioye, O.; Barmada, S. J.; Todd, P. K.
10.1101/2020.05.27.119651 — genetics — Posted on 2020-05-31
6 A novel redox-active switch in Fructosamine-3-kinases expands the regulatory repertoire of the protein kinase superfamily
Shrestha, S.; Katiyar, S.; Sanz-Rodriguez, C. E.; Kemppinen, N. R.; Kim, H. W.; Kadirvelraj, R.; Panagos, C.; Keyhaninejad, N.; Colonna, M.; Chopra, P.; Byrne, D. P.; Boons, G. J.; Knaap, E. V.; Eyers, P.; Edison, A. S.; Wood, Z. A.; Kannan, N.
10.1101/2020.01.13.904870 — biochemistry — Posted on 2020-05-31
13 Field and mesocosm methods to test biodegradable plastic film under marine conditions
Lott, C.; Eich, A.; Unger, B.; Makarow, D.; Battagliarin, G.; Schlegel, K.; Lasut, M. T.; Weber, M.
10.1101/2020.01.31.928606 — ecology — Posted on 2020-05-31
21 A novel mechanism of natural killer cell response to anti-CTLA-4 therapy identified by integrative analysis of mouse and human tumors
Davis-Marcisak, E. F.; Fitzgerald, A. A.; Kessler, M. D.; Danilova, L.; Jaffee, E. M.; Zaidi, N.; Weiner, L. M.; Fertig, E. J.
10.1101/2020.05.31.125625 — cancer biology — Posted on 2020-05-31
23 An interpretable classification method for predicting drug resistance in M. tuberculosis
Zabeti, H.; Dexter, N.; Safari, A. H.; Sedaghat, N.; Libbrecht, M.; Chindelevitch, L.
10.1101/2020.05.31.115741 — bioinformatics — Posted on 2020-05-31
25 Serratia marcescens secretes proteases and chitinases with larvicidal activity against Anopheles dirus
Jupatanakul, N.; Pengon, J.; Selisana, S. M. G.; Choksawangkarn, W.; Jaito, N.; Saeung, A.; Bunyong, R.; Posayapisit, N.; Thammatinna, K.; Kalpongnukul, N.; Aupalee, K.; Pisitkun, T.; Kamchonwongpaisan, S.
10.1101/2020.05.31.123539 — microbiology — Posted on 2020-05-31
26 LINE elements are a reservoir of regulatory potential in mammalian genomes
Roller, M.; Stamper, E.; Villar, D.; Izuogu, O.; Martin, F.; Redmond, A.; Ramachanderan, R.; Harewood, L.; Odom, D. T.; Flicek, P.
10.1101/2020.05.31.126169 — genomics — Posted on 2020-05-31
29 Sofosbuvir protects human brain organoids against SARS-CoV-2
Mesci, P.; Macia, A.; Saleh, A.; Martin-Sancho, L.; YIN, X.; Snethlage, C.; Avansini, S.; Chanda, S.; Muotri, A.
10.1101/2020.05.30.125856 — neuroscience — Posted on 2020-05-31
30 A distinct phylogenetic cluster of Indian SARS-CoV-2 isolates
Banu, S.; Jolly, B.; Mukherjee, P.; Singh, P.; Khan, S.; Zaveri, L.; Shambhavi, S.; Gaur, N.; Mishra, R. K.; Scaria, V.; Sowpati, D. T.
10.1101/2020.05.31.126136 — genomics — Posted on 2020-05-31
31 Origin and cross-species transmission of bat coronaviruses in China
Latinne, A.; Hu, B.; Olival, K. J.; Zhu, G.; Zhang, L.; Li, H.; Chmura, A. A.; Field, H. E.; Zambrana-Torrelio, C.; Epstein, J. H.; Li, B.; Zhang, W.; Wang, L.-F.; Shi, Z.; Daszak, P.
10.1101/2020.05.31.116061 — evolutionary biology — Posted on 2020-05-31
37 Telomere length is highly heritable and independent of growth rate manipulated by temperature in field crickets
Boonekamp, J.; Rodriguez-Munoz, R.; Hopwood, P.; Zuidersma, E.; Mulder, E.; Wilson, A.; Verhulst, S.; Tregenza, T.
10.1101/2020.05.29.123216 — zoology — Posted on 2020-05-31
38 Development of an Ocean Protein Portal for Interactive Discovery and Education
Saito, M.; Saunders, J. K.; Chagnon, M.; Gaylord, D.; Shepherd, A.; Held, N. A.; Dupont, C. L.; Symmonds, N.; York, A.; Charron, M.; Kinkade, D.
10.1101/2020.05.29.124388 — systems biology — Posted on 2020-05-31
39 Obesity phenotypes are preserved in intestinal stem cell enteroids from morbidly obese patients
Hasan, N.; Johnson, K.; Yin, J.; Baetz, N.; Sherman, V.; Blutt, S.; Estes, M. K.; Kumbhari, V.; Zachos, N.; Kovbasnjuk, O.
10.1101/2020.05.29.123737 — physiology — Posted on 2020-05-31
41 Stop the crop: insights into the insecticidal mode of action of cinnamodial against mosquitoes
Kalsi, M.; Walter, A.; Lee, B.; DeLaat, A.; Rusconi Trigueros, R.; Happel, K.; Sepesy, R.; Nguyen, B.; Manwill, P. K.; Rakotondraibe, H. L.; Piermarini, P. M.
10.1101/2020.05.30.125203 — physiology — Posted on 2020-05-31
43 Abuse liability, antinociceptive, and discriminative stimulus properties of IBNtxA
Islam, A.; Rahman, M. A.; Brenner, M.; Moore, A.; Kellmyer, A.; Buechler, H.; DiGiorgio, F.; Verchio, V.; McCracken, L.; Sumi, M.; Hartley, R.; Lizza, J.; Moura-Letts, G.; Ficher, B. D.; Keck, T. M.
10.1101/2020.05.30.125450 — pharmacology and toxicology — Posted on 2020-05-31
44 Physical activity is positively related to local functional connectivity in adolescents' brains
Ruotsalainen, I.; Glerean, E.; Karvanen, J.; Gorbach, T.; Renvall, V.; Syvaoja, H. J.; Tammelin, T. H.; Parviainen, T.
10.1101/2020.05.29.122788 — neuroscience — Posted on 2020-05-31
45 Gray and white matter morphology in substance use disorders: A neuroimaging systematic review and meta-analysis.
Pando-Naude, V.; Toxto, S.; Fernandez-Lozano, S.; Parsons, C. E.; Alcauter, S.; Garza-Villarreal, E. A.
10.1101/2020.05.29.122812 — neuroscience — Posted on 2020-05-31
46 In vivo contactless brain stimulation via non-invasive and targeted delivery of magnetoelectric nanoparticles
Nguyen, T.; Gao, J.; Wang, P.; Nagesetti, A.; Andrew, P.; Masood, S.; Vriesmann, Z.; Liang, P.; Khizroev, S.; Jin, X.
10.1101/2020.05.29.123075 — neuroscience — Posted on 2020-05-31
47 Lynx1 modulates the activity of nAChRs to slow NMJ and muscle fiber degeneration during aging
Vaughan, S. K.; Barbat-Artigas, S.; Myers, T.; Pradham, B. S.; Proszynski, T. J.; Robitaille, R.; Valdez, G.
10.1101/2020.05.29.123851 — neuroscience — Posted on 2020-05-31
50 Herpes Simplex Virus type 1 neuronal infection triggers disassembly of key structural components of dendritic spines
Acuna-Hinrichsen, F.; Covarrubias-Pinto, A.; Ishizuka, Y.; Stolzenbach, M. F.; Martin, C.; Salazar, P.; Castro, M. A.; Bramham, C.; Otth, C.
10.1101/2020.05.30.124958 — neuroscience — Posted on 2020-05-31
55 Neurotrophin receptor activation rescues cognitive and synaptic abnormalities caused by mutation of the psychiatric risk gene Cacna1c
Tigaret, C. M.; Lin, T.-C. E.; Morrell, E.; Sykes, L.; O'Donovan, M. C.; Owen, M. J.; Wilkinson, L. S.; Jones, M. W.; Thomas, K. L.; Hall, J.
10.1101/2020.05.29.123695 — neuroscience — Posted on 2020-05-31
56 Preferential Pharmacological Inhibition of Nav1.6, but not Nav1.1, Abolishes Epileptiform Activity Induced by 4-AP in Mouse Cortical Slices
Patel, R. R.; Ping, X.; Patel, S.; McDermott, J. S.; Krajewski, J. L.; Chi, X. X.; Nisenbaum, E. S.; Jin, X.; Cummins, T. R.
10.1101/2020.05.29.124693 — neuroscience — Posted on 2020-05-31
59 MRI-BASED DEEP LEARNING METHOD FOR DETERMINING METHYLATION STATUS OF THE O6 METHYLGUANINE DNA METHYLTRANSFERASE PROMOTER OUTPERFORMS TISSUE BASED METHODS IN BRAIN GLIOMAS
Bangalore Yogananda, C. G.; Shah, B. R.; Nalawade, S.; Murugesan, G. K.; Yu, F. F.; Pinho, M. C.; Wagner, B. C.; Mickey, B.; Patel, T. R.; Fei, B.; Madhuranthakam, A. J.; Maldjian, J. A.
10.1101/2020.05.30.124230 — neuroscience — Posted on 2020-05-31
67 Dynamic cerebellar network organization across the human menstrual cycle
Fitzgerald, M.; Pritschet, L.; Santander, T.; Grafton, S. T.; Jacobs, E. G.
10.1101/2020.05.29.123869 — neuroscience — Posted on 2020-05-31
73 Functional and Structural Moment Arm Validation for Musculoskeletal Models: A Study of the Human Forearm and Hand
Boots, M. T.; Hardesty, R.; Sobinov, A.; Gritsenko, V.; Collinger, J. L.; Fisher, L. E.; Gaunt, R.; Yakovenko, S.
10.1101/2020.05.29.124644 — neuroscience — Posted on 2020-05-31
74 Dynamin-2 regulates synaptic podosome maturation to facilitate neuromuscular junction development
Lin, S.-S.; Hsieh, T.-L.; Liou, G.-G.; Li, T.-N.; Lin, H.-C.; Chang, C.-W.; Wu, H.-Y.; Yao, C.-K.; Liu, Y.-W.
10.1101/2020.05.30.125062 — molecular biology — Posted on 2020-05-31
76 Interleukin-10 and Small Molecule SHIP1 Allosteric Regulators Trigger Anti-Inflammatory Effects Through SHIP1/STAT3 Complexes
Chamberlain, T. C.; Cheung, S. T.; Yoon, J. S. J.; Ming-Lum, A.; Gill, B. R.; Shakibakho, S.; Dzananovic, E.; Ban, F.; Samiea, A.; Jawanda, K.; Priatel, J.; Krystal, G.; Ong, C. J.; Cherkasov, A.; Andersen, R. J.; McKenna, S. A.; Van Petegem, F.; Mui, A. L.-F.
10.1101/2020.05.29.123943 — immunology — Posted on 2020-05-31
78 Two new immature and dysfunctional neutrophil cell subsets define a predictive signature of sepsis useable in clinical practice
Meghraoui-Kheddar, A.; Chousterman, B. G.; Guillou, N.; Barone, S. M.; Granjeaud, S.; Vallet, H.; Corneau, A.; Guessous, K.; Boissonnas, A.; Irish, J. M.; Combadiere, C.
10.1101/2020.05.29.123992 — immunology — Posted on 2020-05-31
79 Elicitation of broadly protective immunity to influenza by multivalent hemagglutinin nanoparticle vaccines
Boyoglu-Barnum, S.; Ellis, D.; Gillespie, R. A.; Hutchinson, G. B.; Park, Y.-J.; Moin, S. M.; Acton, O.; Ravichandran, R.; Murphy, M.; Pettie, D.; Matheson, N.; Carter, L.; Creanga, A.; Watson, M. J.; Kephart, S.; Vaile, J. R.; Ueda, G.; Crank, M. C.; Stewart, L.; Lee, K. K.; Guttman, M.; Baker, D.; Mascola, J. R.; Veesler, D.; Graham, B.; King, N. P.; Kanekiyo, M.
10.1101/2020.05.30.125179 — immunology — Posted on 2020-05-31
80 Genus-wide characterization of bumblebee genomes reveals variation associated with key ecological and behavioral traits of pollinators
Sun, C.; Huang, J.; Wang, Y.; Zhao, X.; Su, L.; Thomas, G. W. C.; Zhao, M.; Zhang, X.; Jungreis, I.; Kellis, M.; Vicario, S.; Sharakhov, I. V.; Bondarenko, S. M.; Hasselmann, M.; Kim, C. N.; Paten, B.; Penso-Dolfin, L.; Wang, L.; Chang, Y.; Gao, Q.; Ma, L.; Ma, L.; Zhang, Z.; Zhang, H.; Zhang, H.; Ruzzante, L.; Robertson, H. M.; Zhu, Y.; Liu, Y.; Yang, H.; Ding, L.; Wang, Q.; Xu, W.; Liang, C.; Itgen, M. W.; Mee, L.; Sadd, B. M.; Cao, G.; Zhang, Z.; Hahn, M. W.; Schaack, S.; Barribeau, S. M.; Williams, P. H.; Waterhouse, R. M.; Mueller, R. L.
10.1101/2020.05.29.122879 — genomics — Posted on 2020-05-31
82 A high-quality genome assembly and annotation of the gray mangrove, Avicennia marina
Friis, G.; Vizueta, J.; Nelson, D. R.; Khraiwesh, B.; Qudeimat, E.; Salehi-Ashtiani, K.; Ortega, A.; Marshell, A.; Duarte, C. M.; Burt, J. A.
10.1101/2020.05.30.124800 — genomics — Posted on 2020-05-31
84 Reduced Gene Dosage of Histone H4 Prevents CENP-A Mislocalization in Budding Yeast
Basrai, M. A.; Eisenstatt, J. R.; Ohkuni, K.; Preston, O.; Au, W.-C.; Costanzo, M.; Boone, C.
10.1101/2020.05.29.124032 — genetics — Posted on 2020-05-31
85 Rrp1 translocase and ubiquitin ligase activities restrict the genome destabilising effects of Rad51 in fission yeast
Muraszko, J.; Argunhan, B.; Ito, K.; Baranowska, G.; Barg-Wojas, A.; Kramarz, K.; Kurokawa, Y.; Iwasaki, H.; Dziadkowiec, D.
10.1101/2020.05.30.125286 — genetics — Posted on 2020-05-31
87 Elephant genomes reveal insights into differences in disease defense mechanisms between species
Tollis, M.; Ferris, E.; Campbell, M. S.; Harris, V. K.; Rupp, S. M.; Harrison, T. M.; Kiso, W. K.; Schmitt, D. L.; Garner, M. M.; Aktipis, C. A.; Maley, C. C.; Boddy, A. M.; Yandell, M.; Gregg, C.; Schiffman, J. D.; Abegglen, L. M.
10.1101/2020.05.29.124396 — evolutionary biology — Posted on 2020-05-31
89 Deforestation and bird habitat loss in Colombia
Negret, P. J.; Maron, M.; Fuller, R.; Possingham, H.; Watson, J.; Simmonds, J.
10.1101/2020.05.30.125849 — ecology — Posted on 2020-05-31
92 A hydraulic instability drives the cell death decision in the nematode germline
Chartier, N. T.; Mukherjee, A.; Pfanzelter, J.; Früthauer, S.; Larson, B. T.; Fritsch, A. W.; Kreysing, M.; Julicher, F.; Grill, S. W.
10.1101/2020.05.30.125864 — developmental biology — Posted on 2020-05-31
95 Lyn controls chemotaxis and motility of CLL cells via phosphorylation of ROR1.
Dave, Z.; Vondalova-Blanarova, O.; Cada, S.; Janovska, P.; Zezula, N.; Behal, M.; Hanakova, K.; Ganjani, S. R.; Krejci, P.; Gmöryöva, K.; Peschelova, H.; Smida, M.; Zdrahal, Z.; Pavlova, S.; Kotaskova, J.; Pospisilova, S.; Bryja, V.
10.1101/2020.05.29.124156 — cancer biology — Posted on 2020-05-31
96 Intra-tumor heterogeneity of Diffuse Large B-cell Lymphoma involves the induction of diversified stroma-tumor interfaces
Sangaletti, S.; Iannelli, F.; Zanardi, F.; Cancila, V.; Portararo, P.; Botti, L.; Vacca, D.; Chiodoni, C.; Di Napoli, A.; Valenti, C.; Vegliante, M. C.; Pisati, F.; Gulino, A.; Ponzoni, M.; Colombo, M. P.; Tripodo, C.
10.1101/2020.05.30.124859 — cancer biology — Posted on 2020-05-31
98 Metabolic control of tumour extracellular matrix production in cancer-associated fibroblasts
Kay, E. J.; Paterson, K.; Sumpton, D.; Stepanova, E.; Boldrini, C.; Hernandez-Fernaud, J. R.; Dhayade, S.; Gjerga, E.; Shaw, R.; Neilson, L. J.; Koulouras, G.; McGregor, G.; Lilla, S.; Jamieson, C.; Hedley, A.; Johnson, R. M.; Park, M.; Miller, C.; Kamphorst, J.; Loayza-Puch, F.; Saez-Rodriguez, J.; Blyth, K.; Zagnoni, M.; Zanivan, S.
10.1101/2020.05.30.125237 — cancer biology — Posted on 2020-05-31
99 SHP2 Inhibition Abrogates Adaptive Resistance to KRASG12C-Inhibition and Remodels the Tumor Microenvironment of KRAS-Mutant Tumors
Fedele, C.; Li, S.; Teng, K. W.; Foster, C.; Peng, D.; Ran, H.; Mita, P.; Geer, M.; Hattori, T.; Koide, A.; Wang, Y.; Tang, K. H.; Leinwand, J.; Wang, W.; Diskin, B.; Deng, J.; Chen, T.; Dolgalev, I.; Ozerdem, U.; Miller, G.; Koide, S.; Wong, K.-K.; Neel, B. G.
10.1101/2020.05.30.125138 — cancer biology — Posted on 2020-05-31
100 Deletion and overexpression of the scaffolding protein IQGAP1 promotes HCC
Delgado, E. R.; Erickson, H. L.; Tao, J.; Monga, S. P.; Duncan, A. W.; Anakk, S.
10.1101/2020.05.29.124404 — cancer biology — Posted on 2020-05-31
101 Multivalent lipid targeting by the calcium-independent C2A domain of Slp-4/granuphilin
Alnaas, A. A.; Watson-Siriboe, A.; Tran, S.; Negussie, M.; Henderson, J. A.; Osterberg, J. R.; Lee Chon, N.; Oviedo, J.; Lyakhova, T.; Michel, C.; Reisdorph, N.; Reisdorph, R.; Shearn, C. T.; Lin, H.; Knight, J. D.
10.1101/2020.05.29.123596 — biophysics — Posted on 2020-05-31
109 TreeMap: A Structured Approach to Fine Mapping of eQTL Variants
Liu, L.; Chandrashekar, P.; Zeng, B.; Sanderford, M. D.; Kumar, S.; Gibson, G.
10.1101/2020.05.31.125880 — bioinformatics — Posted on 2020-05-31
120 Unexpected Specificity within Dynamic Transcriptional Protein-Protein Complexes
Henley, M. J.; Linhares, B. M.; Morgan, B. S.; Fierke, C. A.; Cierpicki, T.; Mapp, A.
10.1101/2020.05.29.124271 — biochemistry — Posted on 2020-05-31
121 Female rat sexual behavior is unaffected by perinatal fluoxetine exposure
Hegstad, J.; Huijgens, P. T.; Houwing, D. J.; Olivier, J. D.; Heijkoop, R.; Snoeren, E.
10.1101/2020.05.29.122945 — animal behavior and cognition — Posted on 2020-05-31
122 The ubiquitin ligase Hecw controls oogenesis and neuronal homeostasis by promoting the liquid state of ribonucleoprotein particles
Fajner, V.; Giavazzi, F.; Sala, S.; Oldani, A.; Martini, E.; Napoletano, F.; Parazzoli, D.; Cerbino, R.; Maspero, E.; Vaccari, T.; Polo, S.
10.1101/2020.05.30.124933 — animal behavior and cognition — Posted on 2020-05-31
124 Distinct signalling routes mediates intercellular and intracellular rhizobial infection in Lotus japonicus
Montiel, J.; Reid, D. E.; Gronbaek, T. H.; Benfeldt, C. M.; James, E. K.; Ott, T.; Ditengou, F. A.; Nadzieja, M.; Kelly, S.; Stougaard, J.
10.1101/2020.05.29.124313 — plant biology — Posted on 2020-05-31
126 Divergent projections of the prelimbic cortex bidirectionally regulate active avoidance
Diehl, M. M.; Iravedra-Garcia, J. M.; Moran-Sierra, J.; Rojas-Bowe, G.; Gonzalez-Diaz, F. N.; Valentin-Valentin, V. P.; Quirk, G.
10.1101/2020.05.28.120659 — neuroscience — Posted on 2020-05-31
127 Genetically flexible but conserved: a new essential motif in the C-ter domain of HIV-1 group M integrases
Kanja, M.; Cappy, P.; Levy, N.; Oladosu, O.; Schmidt, S.; Rossolillo, P.; Winter, F.; Gasser, R.; Moog, C.; Ruff, M.; Negroni, M.; Lener, D.
10.1101/2020.05.26.118158 — molecular biology — Posted on 2020-05-31
130 Microbial strategies for survival in the glass sponge Vazella pourtalesii
Bayer, K.; Busch, K.; Kenchington, E.; Beazley, L.; Franzenburg, S.; Michels, J.; Hentschel, U.; Slaby, B. M.
10.1101/2020.05.28.122663 — microbiology — Posted on 2020-05-31
133 Regulation of meiotic progression by Sertoli-cell androgen signaling
Larose, H.; Kent, T.; Ma, Q.; Shami, A.; Li, J.; Handel, M.; Hammoud, S. S.
10.1101/2020.05.26.117093 — genetics — Posted on 2020-05-31
135 PP2A-Rts1 antagonizes Rck2-mediated hyperosmotic stress signaling in yeast
Hollenstein, D. M.; Veis, J.; Romanov, N.; Gerecova, G.; Ogris, E.; Hartl, M.; Ammerer, G.; Reiter, W.
10.1101/2020.05.30.124925 — cell biology — Posted on 2020-05-31
137 From wing shape to fluid dynamics in the barn owl (Tyto alba)
Cheney, J. A.; Stevenson, J. P.; Durston, N. E.; Song, J.; Maeda, M.; Windsor, S. P.; Usherwood, J. R.; Bomphrey, R. J.
10.1101/2020.05.29.121178 — zoology — Posted on 2020-05-31
140 Recombination of 2Fe-2S ferredoxins reveals differences in the inheritance of thermostability and midpoint potential
Campbell, I. J.; Kahanda, D.; Atkinson, J. T.; Sparks, O. N.; Kim, J.; Tseng, C.-P.; Verduzco, R.; Bennett, G. N.; Silberg, J. J.
10.1101/2020.05.29.122317 — synthetic biology — Posted on 2020-05-31
142 Silk Fibroin as an Additive for Cell-Free Protein Synthesis
Lee, M. S.; Hung, C.-s.; Phillips, D. A.; Buck, C. C.; Gupta, M. K.; Lux, M. W.
10.1101/2020.05.28.121616 — synthetic biology — Posted on 2020-05-31
145 Three-dimensional understanding of the morphological complexity of the human uterine endometrium
Yamaguchi, M.; Yoshihara, K.; Suda, K.; Nakaoka, H.; Yachida, N.; Ueda, H.; Sugino, K.; Mori, Y.; Yamawaki, K.; Tamura, R.; Ishiguro, T.; Motoyama, T.; Watanabe, Y.; Okuda, S.; Tainaka, K.; Enomoto, T.
10.1101/2020.05.29.118034 — pathology — Posted on 2020-05-31
146 Ventral tegmental area GABA neurons mediate stress-induced anhedonia.
Lowes, D. C.; Chamberlin, L. A.; Kretsge, L. N.; Holt, E. S.; Abbas, A. I.; Park, A. J.; Yusufova, L.; Bretton, Z. H.; Firdous, A.; Gordon, J. A.; Harris, A. Z.
10.1101/2020.05.28.121905 — neuroscience — Posted on 2020-05-31
147 Complement factor C1q mediates chronic neuron loss and inflammation post-brain injury
Holden, S. S.; Aboubakr, O.; Higashikubo, B.; Cho, F. S.; Chang, A. H.; Morningstar, A.; Mathur, V.; Kuhn, L. J.; Suri, P.; Sankaranarayanan, S.; Andrews-Zwilling, Y.; Aronica, E.; Yednock, T.; Paz, J. T.
10.1101/2020.05.29.120220 — neuroscience — Posted on 2020-05-31
149 Axon morphology is modulated by the local environment and impacts the non-invasive investigation of its structure-function relationship
Andersson, M.; Kjer, H. M.; Rafael-Patino, J.; Pacureanu, A.; Pakkenberg, B.; Thiran, J.-P.; Ptito, M.; Bech, M.; Bjorholm Dahl, A.; Andersen Dahl, V.; Dyrby, T. B.
10.1101/2020.05.29.118737 — neuroscience — Posted on 2020-05-31
153 Further biochemical profiling of Hypholoma fasciculare metabolome reveals its chemo-genetic diversity
Al-Salihi, S.; Bull, I.; Al-Salhi, R. A.; Gates, P. J.; Salih, K.; Bailey, A. M.; Foster, G. D.
10.1101/2020.05.28.122176 — molecular biology — Posted on 2020-05-31
157 animalcules: Interactive Microbiome Analytics 1 and Visualization in R
Johnson, W. E.; Federico, A.; Faits, T.; Manimaran, S.; Monti, S.; Zhao, Y.
10.1101/2020.05.29.123760 — microbiology — Posted on 2020-05-31
158 Polymorphisms in STING affect human innate immune responses to poxviruses
Kennedy, R. B.; Haralambieva, I. H.; Ovsyannikova, I. G.; Voigt, E. A.; Larrabee, B.; Schaid, D. J.; Zimmermann, M. T.; Oberg, A. L.; Poland, G. A.
10.1101/2020.05.28.121657 — immunology — Posted on 2020-05-31
159 Divergent cancer etiologies drive distinct B cell signatures and tertiary lymphoid structures
Ruffin, A. T.; Cillo, A. R.; Tabib, T.; Liu, A.; Onkar, S.; Kunning, S.; Lampenfeld, C.; Abecassis, I.; Qi, Z.; Soose, R.; Duvvuri, U. D.; Kim, S.; Oesterreich, S.; Lafyatis, R.; Ferris, R. L.; Vignali, D. A.; Bruno, T. C.
10.1101/2020.05.29.123265 — immunology — Posted on 2020-05-31
160 Escape of TLR5 Recognition by Leptospira spp: A Rationale for Atypical Endoflagella
Holzapfel, M.; Bonhomme, D.; Cagliero, J.; Vernel-Pauillac, F.; Fanton d'Andon, M.; Bortolussi, S.; Fiette, L.; Goarant, C.; Wunder, E.; Picardeau, M.; Ko, A.; Werling, D.; Matsui, M.; Gomberts Boneca, I.; Werts, C.
10.1101/2020.05.30.121202 — immunology — Posted on 2020-05-31
161 Macrophages drive the inflammatory phase in experimental osteoarthritis
Montgomery, A.; Fahy, N.; Hamilton, S.; Eckman, B.; De Almeida, L.; Ishihara, S.; Mayr, M. G.; Chen, S.-Y.; Gadhvi, G.; Cuda, C.; Malfait, A.-M.; Bastiaansen-Jenniskens, Y.; Winter, D. R.
10.1101/2020.05.28.122408 — immunology — Posted on 2020-05-31
162 CREBBP and STAT6 co-mutation and 16p13 and 1p36 loss define the t(14;18)-negative diffuse variant of follicular lymphoma
Xian, R. R.; Xie, Y.; Haley, L. M.; Yonescu, R.; Pallavajjala, A.; Pittaluga, S.; Jaffe, E. S.; Duffield, A. S.; McCall, C. M.; Gheith, S. M. F.; Gocke, C. D.
10.1101/2020.05.28.120212 — genomics — Posted on 2020-05-31
164 Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure
Wang, H.; Noordam, R.; Cade, B. E.; Schwander, K.; Winkler, T. W.; Lee, J.; Sung, Y. J.; Bentley, A. R.; Manning, A. K.; Aschard, H.; Kilpelainen, T. O.; Ilkov, M.; Brown, M. R.; Horimoto, A. R.; Richard, M.; Bartz, T. M.; Vojinovic, D.; Lim, E.; Nierenberg, J. L.; Liu, Y.; Chitrala, K.; Rankinen, T.; Musani, S. K.; Franceschini, N.; Rauramaa, R.; Alver, M.; Zee, P.; Harris, S. E.; van der Most, P. J.; Nolte, I. M.; Munroe, P. B.; Palmer, N. D.; Kuhnel, B.; Weiss, S.; Wen, W.; Hall, K. A.; Lyytikainen, L.-P.; O'Connell, J. R.; Eiriksdottir, G.; Launer, L. J.; de Vries, P. S.; Arking, D.; Chen,
10.1101/2020.05.29.123505 — genomics — Posted on 2020-05-31
166 Epigenome dysregulation resulting from NSD1 mutation in head and neck squamous cell carcinoma
Farhangdoost, N.; Horth, C.; Hu, B.; Bareke, E.; Chen, X.; Li, Y.; Coradin, M.; Garcia, B. A.; Lu, C.; Majewski, J.
10.1101/2020.05.30.124057 — genomics — Posted on 2020-05-31
167 The Caribbean-Hispanic Alzheimer's Brain Transcriptome Reveals Ancestry-Specific Disease Mechanisms
Felsky, D.; Sariya, S.; Santa-Maria, I.; Schneider, J. A.; Bennett, D. A.; Mayeux, R. P.; De Jager, P. L.; Tosto, G.
10.1101/2020.05.28.122234 — genomics — Posted on 2020-05-31
168 Pervasive additive and non-additive effects within the HLA region contribute to disease risk in the UK Biobank
Venkataraman, G. R.; Olivieri, J. E.; DeBoever, C.; Tanigawa, Y.; Justesen, J. M.; Rivas, M. A.
10.1101/2020.05.28.119669 — genetics — Posted on 2020-05-31
169 Marker-assisted selection of trees with MALE STERALITY 1 in Cryptomeria japonica D. Don
Moriguchi, Y.; Ueno, S.; Hasegawa, Y.; Tadama, T.; Watanabe, M.; Saito, R.; Hirayama, S.; Iwai, J.; Konno, Y.
10.1101/2020.05.29.114140 — genetics — Posted on 2020-05-31
170 Population structure of the invasive golden mussel (Limnoperna fortunei) on reservoirs from five Brazilian drainage basins
Rodinho Nunes Ferreira, J. G.; Soares Souza, G. B.; Americo, J. A.; Silva Romao Dumaresq, A.; de Freitas Rebelo, M.
10.1101/2020.05.28.122069 — genetics — Posted on 2020-05-31
175 Core binding factor leukemia hijacks T-cell prone PU.1 antisense promoter
van der Kouwe, E.; Heller, G.; Czibere, A.; Castilla, L. H.; Delwel, R.; Di Ruscio, A.; Ebralidze, A. K.; Forte, M.; Kazianka, L.; Kornauth, C.; Le, T.; Lind, K.; Monteiro Barbosa, I. A.; Pichler, A.; Pulikkan, J. A.; Schmolke, A.-S.; Sill, H.; Sperr, W.; Spittler, A.; Trinh, B. Q.; Valent, P.; Vanura, K.; Welner, R. S.; Zuber, J.; Tenen, D. G.; Staber, P. B.
10.1101/2020.05.29.120857 — cancer biology — Posted on 2020-05-31
176 Loss of malate-aspartate shuttle component SLC25A12 induces pulmonary metastasis
Alkan, H. F.; Vesely, P.; Hackl, H.; Fosselteder, J.; Vander Heiden, M.; Pichler, M.; Hoefler, G.; Bogner-Strauss, J.
10.1101/2020.05.29.121400 — cancer biology — Posted on 2020-05-31
177 HSP90 facilitates oncogenic alterations of metabolism in B-cell lymphomas
Calvo-Vidal, M. N.; Zamponi, N.; Krumsiek, J.; Stockslager, M. A.; Revuelta, M. V.; Phillip, J. M.; Marullo, R.; Kotlov, N.; Patel, J.; Yang, S. N.; Yang, L.; Taldone, T.; Thieblemont, C.; Leonard, J. P.; Martin, P.; Inghirami, G.; Chiosis, G.; Manalis, S. R.; Cerchietti, L.
10.1101/2020.05.29.119925 — cancer biology — Posted on 2020-05-31
181 The mutational landscape of human olfactory G protein-coupled receptors
Cierco, R.; Casajuana, N.; Garcia, A.; Alcantara, L.; Campillo, M.; Pardo, L.; Gonzalez, A.
10.1101/2020.05.29.121103 — bioinformatics — Posted on 2020-05-31
187 25 Years of Pathway Figures
Hanspers, K.; Riutta, A.; Kutmon, M.; Pico, A. R.
10.1101/2020.05.29.124503 — bioinformatics — Posted on 2020-05-31
189 Development of a Tet-On inducible expression system for the anhydrobiotic cell line, Pv11
Tokumoto, S.; Miyata, Y.; Usui, K.; Deviatiiarov, R.; Ohkawa, T.; Kondratieva, S.; Shagimardanova, E.; Gusev, O.; Cornette, R.; Itoh, M.; Hayashizaki, Y.; Kikawada, T.
10.1101/2020.05.29.123570 — bioengineering — Posted on 2020-05-31
191 Structural basis for stereospecific inhibition of ASCT2 from rational design
Garibsingh, R.-A. A.; Ndaru, E.; Garaeva, A. A.; Bonomi, M.; Slotboom, D. J.; Paulino, C.; Grewer, C.; Schlessinger, A.
10.1101/2020.05.29.124305 — biochemistry — Posted on 2020-05-31
192 Structural basis for lipid transport by the MLA complex
Mann, D.; Fan, J.; Farrell, D.; Somboon, K.; Muenks, A.; Tzokov, S.; Khalid, S.; DiMaip, F.; Miller, S.; Bergeron, J.
10.1101/2020.05.30.125013 — biochemistry — Posted on 2020-05-31
198 Alterations of multiple alveolar macrophage states in chronic obstructive pulmonary disease
Bassler, K.; Fujii, W.; Kapellos, T. S.; Horne, A.; Reiz, B.; Dudkin, E.; Luecken, M.; Reusch, N.; Osei-Sarpong, C.; Warnat-Herresthal, S.; Wagner, A.; Bonaguro, L.; Guenther, P.; Pizarro, C.; Schreiber, T.; Becker, M.; Haendler, K.; Wohnhaas, C. T.; Baumgartner, F.; Koehler, M.; Theis, H.; Kraut, M.; Wadsworth, M. H.; Hughes, T. K.; Ferreira, H. J. G.; Schulte-Schrepping, J.; Hinkley, E.; Kaltheuner, I. H.; Geyer, M.; Thiele, C.; Shalek, A. K.; Feisst, A.; Thomas, D.; Dickten, H.; Beyer, M.; Baum, P.; Yosef, N.; Aschenbrenner, A. C.; Ulas, T.; Hasenauer, J.; Theis, F. J.; Skowasch, D.; Schult
10.1101/2020.05.28.121541 — systems biology — Posted on 2020-05-30
201 Impact of rare and common genetic variation in theInterleukin-1 pathway for human cytokine responses
van Deuren, R. C.; Arts, P.; Cavalli, G.; Jaeger, M.; Steehouwer, M.; van de Vorst, M.; Gilissen, C.; Joosten, L. A.; Dinarello, C. A.; Mhlanga, M. M.; Kumar, V.; Netea, M. G.; van de Veerdonk, F. L.; Hoischen, A.
10.1101/2020.02.14.949602 — systems biology — Posted on 2020-05-30
202 Underpinning wheat physiological and molecular responses to co-occurring iron and phosphate deficiency stress
Kaur, G.; Shukla, V.; Meena, V.; Kumar, A.; Singh, J.; Kandoth, P. K.; Mantri, S.; Raouched, H.; Pandey, A. K.
10.1101/2020.05.26.117101 — plant biology — Posted on 2020-05-30
203 Database for drug metabolism and comparisons, NICEdrug.ch, aids discovery and design
MohammadiPeyhani, H.; Chiappino-Pepe, A.; Haddadi, K.; Hafner, J.; Hadadi, N.; Hatzimanikatis, V.
10.1101/2020.05.28.120782 — pharmacology and toxicology — Posted on 2020-05-30
204 Validation and Performance Comparison of Three SARS-CoV-2 Antibody Assays
Lu, S.; Paiva, K. J.; Grisson, R. D.; Chan, P. A.; Lonks, J.; King, E.; Huard, R. C.; Pytel-Parenteau, D. L.; Nam, G. H.; Yakirevich, E.
10.1101/2020.05.29.124776 — pathology — Posted on 2020-05-30
205 SARS-CoV-2 receptor and entry genes are expressed by sustentacular cells in the human olfactory neuroepithelium
Fodoulian, L.; Tuberosa, J.; Rossier, D.; Boillat, M.; Kan, C.-D.; Pauli, V.; Egervari, K.; Lobrinus, J. A.; Landis, B.; Carleton, A.; Rodriguez, I.
10.1101/2020.03.31.013268 — neuroscience — Posted on 2020-05-30
206 Recovery of Consciousness and Cognition after General Anesthesia in Humans
Mashour, G. A.; Palanca, B. J. A.; Basner, M.; Li, D.; Wang, W.; Blain-Moraes, S.; Lin, N.; Maier, K.; Muench, M.; Tarnal, V.; Vanini, G.; Ochroch, E. A.; Hogg, R.; Schwarz, M.; Maybrier, H.; Hardie, R.; Janke, E.; Golmirzaie, G.; Picton, P.; McKinstry-Wu, A.; Avidan, M.; Kelz, M.
10.1101/2020.05.28.121269 — neuroscience — Posted on 2020-05-30
207 Motor corollary discharge activates layer six circuits in the auditory cortex
Clayton, K. K.; Williamson, R. S.; Watanabe, Y.; Hancock, K. E.; Tasaka, G.-i.; Mizrahi, A.; Hackett, T.; Polley, D. B.
10.1101/2020.05.28.121459 — neuroscience — Posted on 2020-05-30
208 Hippocampal subfield volumes across the healthy lifespan and the effects of MR sequence on estimates
Bussy, A.; Plitman, E.; Patel, R.; Tullo, S.; Salaciak, A.; Bedford, S.; Farzin, S.; Beland, M.-L.; Valiquette, V.; Kazazian, C.; Tardif, C.; Devenyi, G.; Chakravarty, M.
10.1101/2020.05.28.121343 — neuroscience — Posted on 2020-05-30
210 Mapping social reward and punishment processing in the human brain: A voxel-based meta-analysis of neuroimaging findings using the Social Incentive Delay task
Martins, D.; Rademacher, L.; Gabay, A.; Taylor, R.; Richey, J.; Smith, D. V.; Goerlich, K.; Nawijn, L.; Cremers, H.; Wilson, R.; Bhattacharyya, S.; Paloyelis, Y.
10.1101/2020.05.28.121475 — neuroscience — Posted on 2020-05-30
213 A Clock-Driven Neural Network Critical for Arousal
Bell, B. J.; Liu, Q.; Kim, D. W.; Lee, S. S.; Liu, Q.; Blum, I. D.; Wang, A.; Bedont, J. L.; Chang, A.; Issa, H.; Cohen, J. Y.; Blackshaw, S.; Wu, M. N.
10.1101/2020.03.12.989921 — neuroscience — Posted on 2020-05-30
216 Dual SMAD inhibition and Wnt inhibition enhances the differentiation of induced pluripotent stem cells into Retinal Ganglion cells (iPSC-RGCs)
Chavali, V. R. M.; Haider, N.; Rathi, S.; Vrathasha, V.; Alapati, T.; He, J.; Gill, K.; Nikonov, S.; Nikonov, R.; Duong, T. T.; McDougald, D. S.; O'Brien, J. M.; Mills, J. A.
10.1101/682666 — neuroscience — Posted on 2020-05-30
220 Structure-based Design of Prefusion-stabilized SARS-CoV-2 Spikes
Hsieh, C.-L.; Goldsmith, J. A.; Schaub, J. M.; DiVenere, A. M.; Kuo, H.-C.; Javanmardi, K.; Le, K. C.; Wrapp, D.; Lee, A. G.-W.; Liu, Y.; Chou, C.-W.; Byrne, P. O.; Hjorth, C. K.; Johnson, N. V.; Ludes-Meyers, J.; Nguyen, A. W.; Park, J.; Wang, N.; Dzifa, A.; Maynard, J. A.; Finkelstein, I. J.; McLellan, J. S.
10.1101/2020.05.30.125484 — microbiology — Posted on 2020-05-30
221 TsaP binds PilQ and is involved in cyclic di-GMP signaling
McCallum, M.; Tammam, S.; Rubinstein, J. L.; Burrows, L. L.; Howell, P. L.
10.1101/2020.05.29.123786 — microbiology — Posted on 2020-05-31
222 Decoding the role of CBLB for innate immune responses regulating systemic dissemination during Non-Tuberculous Mycobacteria infection
Mudalagiriyappa, S.; Sharma, J.; Abdelaal, H. F. M.; Kelly, T. C.; Choi, W.; Vieson, M. D.; Talaat, A. M.; Nanjappa, S. G.
10.1101/2020.05.28.117663 — immunology — Posted on 2020-05-30
225 High accuracy DNA sequencing on a small, scalable platform via electrical detection of single base incorporations
Esfandyarpour, H.; Parizi, K. B.; Rezaei Barmi, M.; Rategh, H.; Wang, L.; Paliwal, S.; Golnabi, H. R.; Kenney, P.; Reel, R.; Lee, F.; Gomes, X.; Stern, S.; Ramachandran, A.; Sankar, S.; Doomson, S.; Ung, R.; Jouzi, M.; Akula Suresh Babu, R.; Nabi, A.; Castillo, N.; Lei, R.; Fallahi, M.; LoPrete, E.; Kemper, A.; Bagchi, S.; Tarbox, R.; Choudhary, P.; Nezamfar, H.; Hsie, L.; Monier, N.; Clark, T. A.; Spence, E.; Yang, F.; Bronson, B.; Sutton, G.; Schweidenback, C.; Lundy, J.; Ho, A.; Tangprasertchai, N.; Thomas, A.; Baxter, B.; Shastry, S.; Barua, A.; Chen, Y.; Hashemzadeh, H.; Shtern, D.; Kim,
10.1101/604553 — genomics — Posted on 2020-05-30
226 The carboxyl-terminus of RAN translated GGGGCC nucleotide repeat expansions modulates toxicity in models of ALS/FTD
He, F.; Flores, B. N.; Krans, A.; Frazer, M.; Natla, S.; Niraula, S.; Adefioye, O.; Barmada, S. J.; Todd, P. K.
10.1101/2020.05.27.119651 — genetics — Posted on 2020-05-30
229 Lateral and longitudinal fish eDNA distribution in dynamic riverine habitats
Thalinger, B.; Kirschner, D.; Puetz, Y.; Moritz, C.; Schwarzenberger, R.; Wanzenboeck, J.; Traugott, M.
10.1101/2020.05.28.120147 — ecology — Posted on 2020-05-30
230 Closed microbial communities self-organize to persistently cycle carbon
de Jesus Astacio, L. M.; Prabhakara, K. H.; Li, Z.; Mickalide, H.; Kuehn, S.
10.1101/2020.05.28.121848 — ecology — Posted on 2020-05-30
232 A single-cell atlas of the mouse and human prostate reveals heterogeneity and conservation of epithelial progenitors
Crowley, L.; Cambuli, F.; Aparicio, L.; Shibata, M.; Robinson, B. D.; Xuan, S.; Li, W.; Hibshoosh, H.; Loda, M.; Rabadan, R.; Shen, M. M.
10.1101/2020.05.29.123836 — developmental biology — Posted on 2020-05-31
234 Direct reprogramming of adult hepatocytes to generate LGR5+ endodermal progenitor
Chaker, D.; Desterke, C.; Moniaux, N.; Ernault, T.; Oudrhiri, N.; Faivre, J.; Turhan, A.; Bennaceur, A.; Griscelli, F.
10.1101/2020.05.29.123273 — developmental biology — Posted on 2020-05-31
236 Frizzled-7 Identifies Platinum Tolerant Ovarian Cancer Cells Susceptible to Ferroptosis
Wang, Y.; Zhao, G.; Condello, S.; Huang, H.; Cardenas, H.; Tanner, E.; Wei, J.-J.; Ji, Y.; Li, J.; Tan, Y.; Davuluri, R.; Cheng, J.-X.; Matei, D.
10.1101/2020.05.28.121590 — cancer biology — Posted on 2020-05-30
237 Hypoxia driven oncometabolite L-2HG maintains "stemness"-differentiation balance and facilitates immune suppression in pancreatic cancer
Gupta, V. K.; Sharma, N. S.; Durden, B.; Garrido, V. T.; Kesh, K.; Edwards, D.; Wang, D.; Myers, C.; Bhattacharya, S. K.; Saluja, A.; Singh, P. K.; Banerjee, S.
10.1101/2020.05.08.084244 — cancer biology — Posted on 2020-05-30
239 Keratin-Based Epidermal Green Autofluorescence is a Common Biomarker of Organ Injury
Zhang, M.; Li, Y.; Wang, J.; Yang, Z.; Wu, D.; Tao, Y.; He, H.; Yang, Z.; Maharjan, D. T.; Tang, H.; Wang, S.; Chen, X.; Jin, L.; Ying, W.
10.1101/564112 — biophysics — Posted on 2020-05-30
240 Unscrambling Fluorophore Blinking for Comprehensive Cluster Detection via Photoactivated Localization Microscopy
Platzer, R.; Rossboth, B. K.; Schneider, M. C.; Sevcsik, E.; Baumgart, F.; Stockinger, H.; Schuetz, G. J.; Huppa, J. B.; Brameshuber, M.
10.1101/545152 — biophysics — Posted on 2020-05-30
242 Correction for both common and rare cell types in blood is important to identify genes that correlate with age
Pellegrino Coppola, D.; Claringbould, A.; Stutvoet, M.; BIOS Consortium, ; Boomsma, D.; Ikram, M. A.; Slagboom, E.; Westra, H.-J.; Franke, L.
10.1101/2020.05.28.120600 — bioinformatics — Posted on 2020-05-30
249 COVID-3D: An online resource to explore the structural distribution of genetic variation in SARS-CoV-2 and its implication on therapeutic development
Portelli, S.; Olshansky, M.; Rodrigues, C. H. M.; D'Souza, E. N.; Myung, Y.; Silk, M.; Alavi, A.; Pires, D. E. V.; Ascher, D. B.
10.1101/2020.05.29.124610 — bioinformatics — Posted on 2020-05-30
252 Evidence for an apathy phenotype in aged mice
Jackson, M. G.; Lightman, S. L.; Gilmour, G.; Marston, H.; Robinson, E. S. J.
10.1101/2020.05.28.121004 — animal behavior and cognition — Posted on 2020-05-30
253 Single-cell Transcriptomics Identifies Gene Expression Networks Driving Differentiation and Tumorigenesis in the Human Fallopian Tube
Dinh, H. Q.; Lin, X.; Abbasi, F.; Nameki, R.; Haro, M.; Olingy, C.; Chang, H.; Hernandez, L.; Gayther, S.; Wright, K. N.; Aspuria, P.-J.; Karlan, B.; Corona, R. I.; Li, A.; Rimel, B.; Siedhoff, M.; Medeiros, F.; Lawrenson, K.
10.1101/2020.05.28.119933 — genomics — Posted on 2020-05-30
254 Impacts of radiation on the bacterial and fungal microbiome of small mammals in the Chernobyl Exclusion Zone
Antwis, R. E.; Beresford, N.; Jackson, J.; Fawkes, R.; Barnett, C.; Potter, E.; Walker, L.; Gaschak, S.; Wood, M.
10.1101/2020.05.28.120717 — ecology — Posted on 2020-05-30
258 A rapid urban biodiversity blitz using aquatic environmental DNA
Hupalo, K.; Majaneva, M.; Czachur, M. V.; Sire, L.; Marquina, D.; Lijtmaer, D. A.; Ivanov, V.; Leidenberger, S.; Ciampor, F.; Ciamporova-Zatovicova, Z.; Mendes, I. S.; Desiderato, A.; Topstad, L.; Meganck, K.; Hariz Z. A., D.; Kjaerstad, G.; Lin, X.-L.; Price, B.; Stevens, M.; Ekrem, T.; Deiner, K.
10.1101/2020.05.27.116905 — scientific communication and education — Posted on 2020-05-30
259 Underpinning wheat physiological and molecular responses to co-occurring iron and phosphate deficiency stress
Kaur, G.; Shukla, V.; Meena, V.; Kumar, A.; Singh, J.; Kandoth, P. K.; Mantri, S.; Raouched, H.; Pandey, A. K.
10.1101/2020.05.26.117101 — plant biology — Posted on 2020-05-29
260 An efficient gene excision system in maize
ANAND, A.; Wang, N.; Arling, M.; Hoerster, G.; Ryan, L.; Wu, E.; Lowe, K.; Gordon-Kamm, W.; Jones, T.; Chilcoat, D.
10.1101/2020.05.26.116996 — plant biology — Posted on 2020-05-29
261 Genome-wide Association Studies Reveal Important Candidate Genes for the Bacillus pumilus TUAT-1-Arabidopsis thaliana Interaction
Soneghett Cotta, M.; Plucani do Amaral, F.; Cruz, L.; Wassem, R.; Pedrosa, F. d. O.; Yokoyama, T.; Stacey, G.
10.1101/2020.05.26.117002 — plant biology — Posted on 2020-05-29
262 Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding.
Yperman, K.; Papageorgiou, A. C.; Merceron, R.; De Munck, S.; Bloch, Y.; Eeckhout, D.; Tack, P.; Evangelidis, T.; Van Leene, J.; Vincze, L.; Vandenabeele, P.; Potocky, M.; De Jaeger, G.; Savvides, S. N.; Tripsianes, K.; Pleskot, R.; Van Damme, D.
10.1101/2020.05.29.122911 — plant biology — Posted on 2020-05-30
263 Host-dependent fungus-fungus competition suppresses fungal pathogenesis in Arabidopsis thaliana
Pathompitaknukul, K.; Hiruma, K.; Tanaka, H.; Kawamura, N.; Toyoda, A.; Itoh, T.; Saijo, Y.
10.1101/2020.05.27.117978 — plant biology — Posted on 2020-05-30
264 Diploid male gametes circumvent hybrid sterility between Asian and African rice species
Kuniyoshi, D.; Masuda, I.; Kanaoka, Y.; Shimazaki-Kishi, Y.; Okamoto, Y.; Yasui, H.; Yamamoto, T.; Nagaki, K.; Hoshino, Y.; Koide, Y.; Takamure, I.; Kishima, Y.
10.1101/2020.05.27.119180 — plant biology — Posted on 2020-05-30
268 A minimally disruptive method for measuring water potential in-planta using hydrogel nanoreporters
Jain, P.; Liu, W.; Zhu, S.; Melkonian, J.; Pauli, D.; Riha, S. J.; Gore, M. A.; Stroock, A. D.
10.1101/2020.05.29.122507 — plant biology — Posted on 2020-05-30
271 A heat-shock inducible system for flexible gene expression in cereals
Harrington, S. A.; Backhaus, A. E.; Fox, S.; Rogers, C.; Borrill, P.; Uauy, C.; Richardson, A.
10.1101/2020.05.29.123554 — plant biology — Posted on 2020-05-30
278 Phosphate and phosphite differentially impact the proteome and phosphoproteome of Arabidopsis suspension cell cultures
Mehta, D.; Ghahremani, M.; Perez-Fernandez, M.; Tan, M.; Schlapfer, P.; Plaxton, W. C.; Uhrig, R. G.
10.1101/2020.05.29.124040 — plant biology — Posted on 2020-05-30
279 Posttranslational modification of the RHO of plants protein RACB by phosphorylation and cross-kingdom conserved ubiquitination
Weiss, L.; Reiner, T.; Mergner, J.; Kuster, B.; Feher, A.; Hensel, G.; Gahrtz, M.; Kumlehn, J.; Engelhardt, S.; Huckelhoven, R.
10.1101/2020.05.28.121228 — plant biology — Posted on 2020-05-30
280 Frequency-independent biological signal identification (FIBSI): A free program that simplifies intensive analysis of non-stationary time series data
Odem, M. A.; Cassidy, R. M.; Bavencoffe, A. G.; Lopez, E. R.; Cheruvu, S. S.; Walters, E. T.; Uribe, R. A.; Krachler, A. M.
10.1101/2020.05.29.123042 — physiology — Posted on 2020-05-29
285 Rapid toxin sequestration impacts poison frog physiology
O'Connell, L. A.; LS50: Integrated Science Laboratory Course, ; O'Connell, J. D.; Paulo, J. A.; Trauger, S. A.; Gygi, S. P.; Murray, A. W.
10.1101/2020.05.27.119081 — physiology — Posted on 2020-05-30
286 Chronic Perinatal Hypoxia Delays Cardiac Maturation in a Mouse Model for Cyanotic Congenital Heart Disease
Romanowicz, J.; Dhari, Z.; Mulvany, C.; Guerrelli, D.; Reilly, M.; Swift, L.; Vasandani, N.; Ramadan, M.; Ishibashi, N.; Posnack, N.
10.1101/2020.05.28.117648 — physiology — Posted on 2020-05-30
289 Distinct Long-term Effects of Precision X-Radiation on Reflex Saliva Flow Rate and Tissue Integrity in a Preclinical Model of Chronic Hyposalivation
Aalam, S. M. M.; Viringipurampeer, I. A.; Walb, M. C.; Tryggestad, E. J.; Emperumal, C. P.; Song, J.; Xu, X.; Saini, R.; Lombaert, I. M. A.; Sarkaria, J. N.; Garcia, J.; Janus, J. R.; Kannan, N.
10.1101/2020.05.26.117937 — pathology — Posted on 2020-05-30
290 The role of sodium thiocyanate supplementation during dextran sodium sulphate-stimulated experimental colitis
Chami, B.; Liu, Y. A.; Burton, T.; Rayner, B. S.; Gabriel, P. S.; Shi, H.; El-Kazzi, M.; Dennis, J.; Ahmad, G.; Witting, P. K.
10.1101/2020.05.27.117994 — pathology — Posted on 2020-05-30
291 Evidence for an Active Role of Inferior Frontal Cortex in Conscious Experience
Weilnhammer, V. A.; Fritsch, M.; Chikermane, M.; Eckert, A.-L.; Kanthak, K.; Stuke, H.; Kaminski, J.; Sterzer, P.
10.1101/2020.05.28.114645 — neuroscience — Posted on 2020-05-30
293 An image resource of subdivided Drosophila GAL4-driver expression patterns for neuron-level searches
Meissner, G. W.; Dorman, Z.; Nern, A.; Forster, K.; Gibney, T.; Jeter, J.; Johnson, L.; He, Y.; Lee, K.; Melton, B.; Yarbrough, B.; Clements, J.; Goina, C.; Otsuna, H.; Rokicki, K.; Svirskas, R. R.; Aso, Y.; Card, G. M.; Dickson, B. J.; Ehrhardt, E.; Goldammer, J.; Ito, M.; Korff, W.; Minegishi, R.; Namiki, S.; Rubin, G. M.; Sterne, G.; Wolff, T.; Malkesman, O.; FlyLight Project Team,
10.1101/2020.05.29.080473 — neuroscience — Posted on 2020-05-30
297 Lapatinib protects against epileptic seizures via halting glutathione peroxidase 4-dependent ferroptosis
Jia, J.-N.; Li, Q.; Sun, Q.-Y.; Yang, N.; Chen, K.-N.; Yin, X.-X.; Zhou, H.-H.; Mao, X.-Y.
10.1101/2020.05.28.120733 — neuroscience — Posted on 2020-05-30
298 Accumbens cholinergic interneurons mediate cue-induced nicotine seeking and associated glutamatergic plasticity
Leyrer-Jackson, J.; Holter, M. C.; Overby, P.; Newbern, J.; Scofield, M.; Olive, F.; Gipson, C. D.
10.1101/2020.05.28.119222 — neuroscience — Posted on 2020-05-30
299 On the complexity of resting state spiking activity in monkey motor cortex
Dabrowska, P. A.; Voges, N.; von Papen, M.; Ito, J.; Dahmen, D.; Riehle, A.; Brochier, T.; Grün, S.
10.1101/2020.05.28.121095 — neuroscience — Posted on 2020-05-30
300 Insulin-like growth factor 2 (IGF2) protects against Huntington's disease through the extracellular disposal of protein aggregates
Garcia-Huerta, P.; Troncoso-Escudero, P.; Wu, D.; Thiruvalluvan, A.; Cisternas, M.; Henriquez, D. R.; Plate, L.; Chana-Cuevas, P.; Sequel, C.; Thielen, P.; Longo, K. A.; Geddes, B. J.; Lederkremer, G.; Sharma, N.; Shenkman, M.; Naphade, S.; Sardi, P.; Spichiger, C.; Richter, H. G.; Court, F.; Ellerby, L.; Wiseman, L.; Gonzalez-Billault, C.; Bergink, S.; Vidal, R. L.; Hetz, C.
10.1101/2020.05.28.119164 — neuroscience — Posted on 2020-05-30
301 An enhanced isothermal amplification assay for viral detection
Qian, J.; Boswell, S. A.; Chidley, C.; Lu, Z.-x.; Pettit, M. E.; Gaudio, B. L.; Fajnzylber, J. M.; Ingram, R. T.; Ward, R. H.; Li, J. Z.; Springer, M.
10.1101/2020.05.28.118059 — molecular biology — Posted on 2020-05-29
302 SYBR Green-based one-step qRT-PCR for the detection of SARS-CoV-2 RNA in saliva
Ganguly, D. R.; Rottet, S.; Yee, S.; Hee, W. Y.; Smith, A. B.; Khin, N. C.; Millar, T.; Fahrer, A.
10.1101/2020.05.29.109702 — molecular biology — Posted on 2020-05-29
303 Development Optimization and Validation of RT-LAMP based COVID-19 Facility in Pakistan
Haq, F.; Sharif, S.; Khurshid, A.; Shabbir, I.; Salman, M.; Badar, N.; Ikram, A.; Ahad, A.; Malik, M. F.
10.1101/2020.05.29.124123 — molecular biology — Posted on 2020-05-29
304 Comparison Of Different Kits For SARS-CoV-2 RNA Extraction Marketed In Brazil
Eisen, A. K. A.; Demoliner, M.; Gularte, J. S.; Hansen, A. W.; Schallenberger, K.; Mallmann, L.; Hermann, B. S.; Heldt, F. H.; de Almeida, P. R.; Fleck, J. D.; Spilki, F. R.
10.1101/2020.05.29.122358 — molecular biology — Posted on 2020-05-29
305 TSPAN1 promotes human pancreatic cancer cells proliferation by modulating CDK1 via Akt
shi, g.; WANG, X.; GAO, Z. X.; tian, x. j.; ZHANG, R.; qiao, y.; Hua, d. x.; Zhang rui,Ma shiyang,
10.1101/2020.05.29.123091 — molecular biology — Posted on 2020-05-29
307 Detecting nanoscale distribution of protein pairs by proximity dependent super-resolution microscopy
Clowsley, A. H.; Kaufhold, W. T.; Lutz, T.; Meletiou, A.; Di Michele, L.; Soeller, C.
10.1101/591081 — molecular biology — Posted on 2020-05-30
308 Detecting nanoscale distribution of protein pairs by proximity dependent super-resolution microscopy
Clowsley, A. H.; Kaufhold, W. T.; Lutz, T.; Meletiou, A.; Di Michele, L.; Soeller, C.
10.1101/591081 — molecular biology — Posted on 2020-05-30
309 Reduced RNA turnover as a driver of cellular senescence
Mullani, N.; Porozhan, Y.; Costallat, M.; Batsche, E.; Goodhardt, M.; Cenci, G.; Mann, C.; Muchardt, C.
10.1101/800128 — molecular biology — Posted on 2020-05-30
310 Reduced RNA turnover as a driver of cellular senescence
Mullani, N.; Porozhan, Y.; Costallat, M.; Batsche, E.; Goodhardt, M.; Cenci, G.; Mann, C.; Muchardt, C.
10.1101/800128 — molecular biology — Posted on 2020-05-30
314 Viral-Induced Alternative Splicing of Host Genes Promotes Influenza Replication
Thompson, M. G.; Dittmar, M.; Mallory, M. J.; Bhat, P.; Ferretti, M. B.; Fontoura, B. M.; Cherry, S.; Lynch, K. W.
10.1101/2020.05.28.122044 — molecular biology — Posted on 2020-05-30
315 Selective antibiofilm properties and biocompatibility of nano-ZnO and nano-ZnO/Ag coated surfaces
Rosenberg, M.; Visnapuu, M.; Vija, H.; Kisand, V.; Kasemets, K.; Kahru, A.; Ivask, A.
10.1101/2020.03.18.996967 — microbiology — Posted on 2020-05-30
318 Shared PKS modules in biosynthesis of synergistic laxaphycins
Heinilä, L. M. P.; Fewer, D. P.; Jokela, J. K.; Wahlsten, M.; Jortikka, A.; Sivonen, K.
10.1101/2020.05.29.098152 — microbiology — Posted on 2020-05-30
321 Head-to-head comparison of four antigen-based rapid detection tests for the diagnosis of SARS-CoV-2 in respiratory samples
Weitzel, T.; Legarraga, P.; Iruretagoyena, M.; Pizarro, G.; Vollrath, V.; Araos, R.; Munita, J. M.; Porte, L.
10.1101/2020.05.27.119255 — microbiology — Posted on 2020-05-30
322 Expansion of SARS-CoV-2-specific Antibody-secreting Cells and Generation of Neutralizing Antibodies in Hospitalized COVID-19 Patients
Varnaite, R.; Garcia, M.; Glans, H.; Maleki, K. T.; Sandberg, J. T.; Tynell, J.; Christ, W.; Lagerqvist, N.; Asgeirsson, H.; Ljunggren, H.-G.; Ahlen, G.; Frelin, L.; Sällberg, M.; Blom, K.; Klingström, J.; Gredmark-Russ, S.
10.1101/2020.05.28.118729 — immunology — Posted on 2020-05-29
323 Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies
Barnes, C. O.; West, A. P.; Huey-Tubman, K.; Hoffmann, M. A. G.; Sharaf, N. G.; Hoffman, P. R.; Koranda, N.; Gristick, H. B.; Gaebler, C.; Muecksch, F.; Cetrulo Lorenzi, J. C.; Finkin, S.; Hagglof, T.; Hurley, A.; Millard, K. G.; Weisblum, Y.; Schmidt, F.; Hatziioannou, T.; Bieniasz, P. D.; Caskey, M.; Robbiani, D.; Nussenzweig, M. C.; Bjorkman, P. J.
10.1101/2020.05.28.121533 — immunology — Posted on 2020-05-29
324 Severe dysregulation of TNF expression leads to multiple inflammatory diseases and embryonic death
Bouillet, P.; Clayer, E.; Dalseno, D.; Kueh, A. J.; Lacey, D.; Tsai, M.; Carr, E.; Wimmer, V.
10.1101/2020.05.28.120501 — immunology — Posted on 2020-05-29
327 Identification of HIV-Transmitting Sub-Epithelial Mononuclear Phagocytes in Human Anogenital and Colorectal Tissues
Rhodes, J. W.; Botting, R. A.; Bertram, K. M.; Rana, H.; Baharlou, H.; Longmuir-Vine, E. E.; Vegh, P.; Fletcher, J.; O'Neil, T. R.; Parnell, G. P.; Graham, D.; Nasr, N.; Lim, J. J. K.; Barnouti, L.; Haertsch, P.; Gosselink, M. P.; Di Re, A.; Ctercteko, G.; Jenkins, G. J.; Brooks, A. J.; Patrick, E.; Byrne, S. N.; Haniffa, M. A.; Cunningham, A. L.; Harman, A. N.
10.1101/2020.05.26.117408 — immunology — Posted on 2020-05-29
329 CAR T cell entry into tumor islets is a two-step process dependent on IFNγ and ICAM-1
Kantari-Mimoun, C.; Barrin, S.; Haghiri, S.; Gervais, C.; Mittelstaet, J.; Mockel-Tenbrinck, N.; Kinkhabwala, A.; Damotte, D.; Lupo, A.; Sibony, M.; Alifano, M.; Vimeux, L.; Dondi, E.; Bercovici, N.; Trautmann, A.; Kaiser, A.; Donnadieu, E.
10.1101/2020.05.27.119198 — immunology — Posted on 2020-05-30
330 Wnt Signalling Orchestrates the Immune Response and Cardiac Damage During Trypanosoma cruzi Infection
Volpini, X.; Ambrosio, L. F.; Brajin, A.; Brugo, M. B.; Aoki, M. P.; Rivarola, H. W.; Alfonso, F.; Fozzatti, L.; Cervi, L.; Motran, C. C.
10.1101/2020.05.27.119107 — immunology — Posted on 2020-05-30
332 The clonal and molecular aetiology of emergency dendritic cell development
Lin, D. S.; Tian, L.; Tomei, S.; Amann-Zalcenstein, D.; Baldwin, T. M.; Weber, T. S.; Schreuder, J.; Stonehouse, O.; Rautela, J.; Huntington, N. D.; Ng, A. P.; Nutt, S. L.; Taoudi, S.; Ritchie, M. E.; Hodgkin, P. D.; Naik, S. H.
10.1101/2020.05.28.120188 — immunology — Posted on 2020-05-30
334 SARS-CoV-2 transmission chains from genetic data: a Danish case study
Bluhm, A.; Christandl, M.; Gesmundo, F.; Ravn Klausen, F.; Mancinska, L.; Steffan, V.; Stilck Franca, D.; Werner, A.
10.1101/2020.05.29.123612 — genomics — Posted on 2020-05-29
336 Chromatin arranges in chains of mesoscale domains with nanoscale functional topography independent of cohesin
Miron, E.; Oldenkamp, R.; Brown, J. M.; Pinto, D. M.; Xu, C. S.; Faria, A. R.; Shaban, H. A.; Rhodes, J. D.; Innocent, C.; de Ornellas, S.; Hess, H.; Buckle, V.; Schermelleh, L.
10.1101/566638 — genomics — Posted on 2020-05-30
337 Insights into the evolution of symbiosis gene copy number and distribution from a chromosome-scale Lotus japonicus Gifu genome sequence
Kamal, N.; Mun, T.; Reid, D.; Lin, J.-s.; Akyol, T. Y.; Sandal, N.; Asp, T.; Hirakawa, H.; Stougaard, J.; Mayer, K. F. X.; Sato, S.; Andersen, S. U.
10.1101/2020.04.17.042473 — genomics — Posted on 2020-05-30
341 A chromosome-level genome assembly of the woolly apple aphid, Eriosoma lanigerum (Hausmann) (Hemiptera: Aphididae)
Biello, R.; Singh, A.; Godfrey, C. J.; Fernandez, F. F.; Mugford, S. T.; Powell, G.; Hogenhout, S. A.; Mathers, T. C.
10.1101/2020.05.29.121947 — genomics — Posted on 2020-05-30
344 Long read sequencing and de novo assembly of Hepatitis B Virus identifies 5mCpG in CpG islands
Goldsmith, C. D.; Cohen, D.; Dubois, A.; Martinez, M.-G.; Petitjean, K.; Corlu, A.; Hernandez-Vargas, H.; Chemin, I.
10.1101/2020.05.29.122259 — genomics — Posted on 2020-05-30
345 Germline ERBB3 mutation in familial non-small cell lung carcinoma: expanding the role of the ErbB family in oncogenesis.
McInerney-Leo, A. M.; Chew, H. Y.; Inglis, P.-L.; Leo, P. J.; Joseph, S. R.; Cooper, C. L.; Okano, S.; Hassall, T.; Anderson, L.; Bowman, R. V.; Gattas, M.; Harris, J. E.; Marshall, M. S.; Shaw, J. G.; Wheeler, L.; Yang, I. A.; Brown, M. A.; Fong, K. M.; Simpson, F.; Duncan, E. L.
10.1101/2020.05.29.122796 — genomics — Posted on 2020-05-30
346 Understanding the diversity of DNA methylation in Mycobacterium tuberculosis
Ndhlovu, V.; Kiran, A.; Sloan, D. J.; Mandala, W.; Nliwasa, M.; Everett, D. B.; Mwapasa, M.; Kontogianni, K.; Kamdolozi, M.; Corbett, E. L.; Caws, M.; Davies, G.
10.1101/2020.05.29.117077 — genomics — Posted on 2020-05-30
349 Lineage tracing of human embryonic development and foetal haematopoiesis through somatic mutations
Spencer Chapman, M.; Ranzoni, A. M.; Myers, B.; Williams, N.; Coorens, T.; Mitchell, E.; Butler, T.; Dawson, K. J.; Hooks, Y.; Moore, L.; Nangalia, J.; Robinson, P. S.; Hook, E.; Campbell, P. J.; Cvejic, A.
10.1101/2020.05.29.088765 — genomics — Posted on 2020-05-30
352 Genomic analysis of early SARS-CoV-2 strains introduced in Mexico
Taboada, B.; Vazquez-Perez, J. A.; Munoz-Medina, J. E.; Ramos-Cervantes, P.; Escalera-Zamudio, M.; Boukadida, C.; Sanchez-Flores, A.; Pavel, I.; Mendieta-Condado, E.; Martinez-Orozco, J. A.; Becerril-Vargas, E.; Salas-Hernandez, J.; Grande, R.; Gonzalez-Torres, C.; Gaytan-Cervantes, F. J.; Vazquez, G.; Pulido, F.; Araiza-Rodriguez, A.; Garces-Ayala, F.; Gonzalez-Bonilla, C. R.; Grajales-Muniz, C.; Borja-Aburto, V. H.; Barrera-Badillo, G.; Lopez, S.; Hernandez-Rivas, L.; Perez-Padilla, R.; Lopez Martinez, I.; Avila-Rios, S.; Ruiz-Palacios, G.; Ramirez-Gonzalez, J. E.; Arias, C. F.
10.1101/2020.05.27.120402 — genomics — Posted on 2020-05-30
357 A pedigree-based prediction model identifies carriers of deleterious de novo mutations in families with Li-Fraumeni syndrome
Gao, F.; Pan, X.; Dodd-Eaton, E. B.; Vera Recio, C. C.; Montierth, M. D.; Bojadzieva, J.; Mai, P. L.; Zelley, K.; Johnson, V. E.; Braun, D.; Nichols, K. E.; Garber, J. E.; Savage, S. A.; Strong, L. C.; Wang, W.
10.1101/2020.02.10.942409 — genetics — Posted on 2020-05-30
358 Genetic effects on educational attainment in Hungary
Ujma, P. P.; Eszlari, N.; Millinghoffer, A.; Bruncsics, B.; Petschner, P.; Antal, P.; Deakin, B.; Breen, G.; Bagdy, G.; Juhasz, G.
10.1101/2020.01.13.905034 — genetics — Posted on 2020-05-30
360 Mice lacking paternal expression of imprinted Grb10 are risk-takers
Dent, C. L.; Reinecker, K. D.; Ward, A.; Wilkins, J. F.; Humby, T.; Isles, A.
10.1101/2020.02.25.962399 — genetics — Posted on 2020-05-30
364 The carboxyl-terminus of RAN translated GGGGCC nucleotide repeat expansions modulates toxicity in models of ALS/FTD
He, F.; Flores, B. N.; Krans, A.; Frazer, M.; Natla, S.; Niraula, S.; Adefioye, O.; Barmada, S. J.; Todd, P. K.
10.1101/2020.05.27.119651 — genetics — Posted on 2020-05-30
365 The variant call format provides efficient and robust storage of GWAS summary statistics
Lyon, M. S.; Andrews, S. J.; Elsworth, B. L.; Gaunt, T. R.; Hemani, G.; Marcora, E.
10.1101/2020.05.29.115824 — genetics — Posted on 2020-05-30
366 Rare variant analysis of 4,241 pulmonary arterial hypertension cases from an international consortium implicate FBLN2, PDGFD and rare de novo variants in PAH
Zhu, N.; Swietlik, E. M.; Welch, C. L.; Pauciulo, M. W.; Hagen, J. J.; Zhou, X.; Guo, Y.; Karten, J.; Pandya, D.; Tilly, T.; Lutz, K. A.; Rosenzweig, E.; Krishnan, U.; Coleman, A. W.; Gonzaga-Juaregiu, C.; Lawrie, A.; Trembath, R. C.; Wilkins, M. R.; Regeneron Genetics Group, ; PAH Biobank Enrolling Centers' Investigators, ; NIHR BioResource for Translational Research - Rare Diseases, ; National Cohort Study of Idiopathic and Heritable PAH, ; Morrell, N. W.; Shen, Y.; Graf, S.; Nichols, W. C.; Chung, W. K.
10.1101/2020.05.29.124255 — genetics — Posted on 2020-05-30
368 Evidence of significant natural selection in the evolution of SARS-CoV-2 in bats, not humans
MacLean, O. A.; Lytras, S.; Singer, J. B.; Weaver, S.; Kosakovsky Pond, S. L.; Robertson, D. L.
10.1101/2020.05.28.122366 — evolutionary biology — Posted on 2020-05-29
369 The gene cortex controls scale colour identity in Heliconius
Livraghi, L.; Hanly, J. J.; Loh, L. S.; Ren, A.; Warren, I. A.; Concha, C.; Wright, C.; Walker, J. M.; Foley, J.; Arenas-Castro, H.; Brenes, L. R.; Martin, A.; McMillan, W. O.; Jiggins, C. D.
10.1101/2020.05.26.116533 — evolutionary biology — Posted on 2020-05-29
371 A genomic footprint of a moving hybrid zone in marbled newts
Arntzen, J. W.; Lopez-Delgado, J.; van Riemsdijk, I.; Wielstra, B.
10.1101/2020.05.27.118448 — evolutionary biology — Posted on 2020-05-30
377 A target enrichment probe set for resolving the flagellate plant tree of life
Breinholt, J. W.; Carey, S. B.; Tiley, G. P.; Davis, E. C.; Endara, L.; McDaniel, S. F.; Neves, L. G.; Sessa, E. B.; von Konrat, M.; Chantanaorrapint, S.; Fawcett, S.; Ickert-Bond, S. M.; Labiak, P. H.; Larrain, J.; Lehnert, M.; Nagalingum, N. S.; Patel, N.; Rensing, S. A.; Testo, W.; Vasco, A.; Villarreal, J. C.; Williams, E. W.; Burleigh, J. G.
10.1101/2020.05.29.124081 — evolutionary biology — Posted on 2020-05-30
389 Identifying Mangrove-Coral Habitats in the Florida Keys
Kellogg, C. A.; Moyer, R. P.; Jacobsen, M.; Yates, K. K.
10.1101/2020.05.27.119727 — ecology — Posted on 2020-05-30
392 Indigenous plants promote insect biodiversity in urban greenspaces
Mata, L.; Andersen, A. N.; Moran-Ordonez, A.; Hahs, A. K.; Backstrom, A.; Ives, C. D.; Bickel, D.; Duncan, D.; Palma, E.; Thomas, F.; Cranney, K.; Walker, K.; Shears, I.; Semeraro, L.; Malipatil, M.; Moir, M. L.; Plein, M.; Porch, N.; Vesk, P. A.; Smith, T. R.; Lynch, Y.
10.1101/2020.05.29.122572 — ecology — Posted on 2020-05-30
393 Habitat fragmentation and food security in crop pollination systems
Montoya, D.; Haegeman, B.; Gaba, S.; De Mazancourt, C.; Loreau, M.
10.1101/2020.05.28.120550 — ecology — Posted on 2020-05-30
396 Establishment and maintenance of motor neuron identity via temporal modularity in terminal selector function
Li, Y.; Osuma, A.; Correa, E.; Okebalama, M.; Dao, P.; Gaylord, O.; Aburas, J.; Islam, P.; Brown, A. E. X.; Kratsios, P.
10.1101/2020.05.06.080184 — developmental biology — Posted on 2020-05-30
398 An extracellular protein regulates patched-related/DAF-6-mediated sensory compartment formation in C. elegans
Hong, H.; Chen, H.; Zhang, Y.; Wu, Z.; Zhang, Y.; Zhang, Y.; Hu, Z.; Zhang, J.; Lin, K.; Hu, J.; Wei, Q.
10.1101/2020.05.29.123182 — developmental biology — Posted on 2020-05-30
399 Tumor-free elongation of mammalian nephrogenesis by excess fetal GDNF
Li, H.; Kupari, J.; Gui, Y.; Siefker, E.; Lu, B.; Mätlik, K.; Olfat, S.; Montano-Rodriguez, A. R.; Huh, S.-H.; Costantini, F. D.; Andressoo, J.-O.; Kuure, S.
10.1101/2020.05.28.120865 — developmental biology — Posted on 2020-05-30
400 Analysis of gene network bifurcation during optic cup morphogenesis in zebrafish
Bono, L.; Naranjo, S.; Moreno-Marmol, T.; de la Cerda, B.; Polvillo, R.; Diaz-Corrales, F. J.; Bogdanovic, O.; Bovolenta, P.; Martinez-Morales, J.-R.
10.1101/2020.05.28.121038 — developmental biology — Posted on 2020-05-30
402 The Arp1/11 Minifilament of Dynactin Primes the Endosomal Arp2/3 Complex
Fokin, A. I.; David, V.; Oguievetskaia, K.; Derivery, E.; Stone, C. E.; Cao, L.; Rocques, N.; Molinie, N.; Henriot, V.; Aumont-Nicaise, M.; Hinckelmann, M. V.; SAUDOU, F.; Le Clainche, C.; Carter, A. P.; Romet-Lemonne, G.; Gautreau, A. M.
10.1101/2020.05.29.123372 — cell biology — Posted on 2020-05-29
403 drICE restrains DIAP2-mediated inflammatory signalling and intestinal inflammation
Kietz, C.; Pollari, V.; Tuominen, I.-E.; Ribeiro, P. S.; Meier, P.; Meinander, A.
10.1101/2020.05.29.122978 — cell biology — Posted on 2020-05-29
405 AMPK regulates cell shape of cardiomyocytes by modulating turnover of microtubules through CLIP-170
Shintani, Y.; Yashirogi, S.; Katayama, T.; Nagao, T.; Nishida, Y.; Kioka, H.; Matsui, T. S.; Saito, S.; Masumura, Y.; Tsukamoto, O.; Kato, H.; Yazawa, I.; Ueda, H.; Tsukamoto, O.; Yashiro, K.; Yamazaki, S.; Takeshima, S.
10.1101/2020.05.29.123299 — cell biology — Posted on 2020-05-29
409 Effects of Post-Myocardial Infarction Heart Failure on the Bone Vascular Niche
Hoffmann, J.; Luxan, G.; Abplanalp, W. T.; Glaser, S.-F.; Rasper, T.; Fischer, A.; Muhly-Reinholz, M.; John, D.; Assmus, B.; Zeiher, A. M.; Dimmeler, S.
10.1101/2020.05.29.123711 — cell biology — Posted on 2020-05-30
410 The immunophilin Zonda controls regulated exocytosis in endocrine and exocrine tissues
de la Riva Carrasco, R. V.; Perez Pandolfo, S.; Suarez Freire, S.; Romero, N. M.; Bhujabal, Z.; Johansen, T.; Wappner, P.; Melani, M.
10.1101/2020.05.28.122465 — cell biology — Posted on 2020-05-30
411 SARS-CoV-2 infection induces EMT-like molecular changes, including ZEB1-mediated repression of the viral receptor ACE2, in lung cancer models
Stewart, C. A.; Gay, C. M.; Ramkumar, K.; Cargill, K. R.; Cardnell, R. J.; Nilsson, M. B.; Heeke, S.; Park, E. M.; Kundu, S. T.; Diao, L.; Wang, Q.; Shen, L.; Xi, Y.; Della Corte, C. M.; Fan, Y.; Kundu, K.; Pickering, C. R.; Johnson, F. M.; Zhang, J.; Kadara, H.; Minna, J. D.; Gibbons, D. L.; Wang, J.; Heymach, J. V.; Byers, L. A.
10.1101/2020.05.28.122291 — cancer biology — Posted on 2020-05-29
413 Identification of oncolytic vaccinia restriction factors in canine high-grade mammary tumor cells using single-cell transcriptomics
Cambien, B.; Lebrigand, K.; Baeri, A.; Nottet, N.; Compin, C.; Lamit, A.; Ferraris, O.; Peyrefitte, C.; Magnone, V.; Henriques, J.; Zaragosi, L.-E.; Giorgetti-Peraldi, S.; Bost, F.; Gautier-Isola, M.; Rezzonico, R.; Barbry, P.; Barthel, R.; Mari, B.; Vassaux, G.
10.1101/2020.05.29.123133 — cancer biology — Posted on 2020-05-29
414 Polymer-assisted intratumoral delivery of ethanol: Preclinical investigation of safety and efficacy in a murine breast cancer model
Nief, C.; Morhard, R.; Chelales, E.; Adrianzen Alvarez, D.; Bourla, I.; Lam, C. T.; Crouch, B.; Sag, A. A.; Mueller, J. L.; Katz, D.; Dewhirst, M. W.; Everitt, J. I.; Ramanujam, N.
10.1101/2020.05.29.123125 — cancer biology — Posted on 2020-05-29
415 Ablation of MYB-dependent leukaemia phenotype in MLL-driven AML correlates with increased expression of MAFB.
Ward, C.; Cauchy, P.; Walton, D. S.; Clarke, M. L.; Blakemore, D.; Grebien, F.; Garcia, P.; Frampton, J.; Volpe, G.
10.1101/2020.05.27.118828 — cancer biology — Posted on 2020-05-30
416 N-acetylaspartate improves cell survival when glucose is limiting
Alkan, H. F.; Walter, K. E.; Hackl, H.; Vander Heiden, M.; Madl, T.; Bogner-Strauss, J.
10.1101/2020.05.28.114629 — cancer biology — Posted on 2020-05-30
417 Netrin G1 promotes pancreatic tumorigenesis through cancer associated fibroblastdriven nutritional support and immunosuppression
Francescone, R.; Barbosa Vendramini-Costa, D.; Franco-Barraza, J.; Wagner, J.; Muir, A.; Lau, A. N.; Gabitova, L.; Pazina, T.; Gupta, S.; Luong, T.; Shah, N.; Rollins, D.; Malik, R.; Thapa, R.; Restifo, D.; Zhou, Y.; Cai, K. Q.; Hensley, H. H.; Tan, Y.; Kruger, W. D.; Devarajan, K.; Balachandran, S.; Klein-Szanto, A. J.; Wang, H.; El-Deiry, W. S.; Vander Heiden, M. G.; Peri, S.; Campbell, K. S.; Astsaturov, I.; Cukierman, E.
10.1101/330209 — cancer biology — Posted on 2020-05-30
418 Kinobead Profiling Reveals Reprogramming of B-cell Receptor Signaling in Response to Therapy Within Primary Chronic Lymphocytic Leukemia Cells.
Linley, A. J.; Karydis, L.; Mondru, A.; D'Avola, A.; Cicconi, S.; Griffin, R.; Forconi, F.; Pettitt, A. R.; Kalakonda, N.; Rawstron, A.; Hillmen, P.; Steele, A. J.; MacEwan, D. J.; Packham, G.; Prior, I.; Slupsky, J.
10.1101/841312 — cancer biology — Posted on 2020-05-30
419 Effects of germline and somatic events in candidate BRCAness genes on breast-tumor signatures
Bodily, W. R.; Shirts, B. H.; Walsh, T.; Gulsuner, S.; King, M.-C.; Parker, A.; Roosan, M.; Piccolo, S. R.
10.1101/662874 — cancer biology — Posted on 2020-05-30
420 Pharmacologically modified pluripotent stem cell-based cancer vaccines with anti-metastatic potential
Heront-Kishi, M.; Asgorava, A.; Desterke, C.; Chaker, D.; de Goer, M. G.; TURHAN, A.; Bennaceur, A.; Griscelli, F.
10.1101/2020.05.27.118471 — cancer biology — Posted on 2020-05-30
422 Non-canonical glutamate-cysteine ligase activity protects against ferroptosis
Kang, Y. P.; Mockabee-Macias, A.; Jiang, C.; Harris, I. S.; DeNicola, G. M.
10.1101/2020.05.29.123802 — cancer biology — Posted on 2020-05-30
423 Inhibition of tryptophan-2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells
Reed, M. R.; Maddukuri, L.; Ketkar, A.; Byrum, S. D.; Zafar, M. K.; Bostian, A. C. L.; Tackett, A. J.; Eoff, R. L.
10.1101/2020.05.28.110874 — cancer biology — Posted on 2020-05-30
424 Tumor-Immune Partitioning and Clustering (TIPC) algorithm reveals distinct signatures of tumor-immune cell interactions within the tumor microenvironment
Lau, M. C.; Borowsky, J.; Vayrynen, J. P.; Haruki, K.; Zhao, M.; Dias Costa, A.; Gu, S.; Silva, A. d.; Arima, K.; Yeong, J.; Felt, K. D.; Hamada, T.; Nishihara, R.; Lennerz, J. K.; Fuchs, C. S.; Wu, C. J.; Ogino, S.; Nowak, J. A.
10.1101/2020.05.29.111542 — cancer biology — Posted on 2020-05-30
425 The MNK1/2-eIF4E axis contributes to phenotype switching, melanoma progression, and resistance to immunotherapy.
Huang, F.; Goncalves, C.; Bartish, M.; Remy-Sarrazin, J.; Guo, Q.; Emond, A.; Yang, W.; Plourde, D.; Su, J.; Gimeno, M. G.; Zhan, Y.; Attias, M.; Galan, A.; rzymski, T.; Mazan, M.; Masiejczyk, M.; Faber, J.; Khoury, E.; Benoit, A.; Gagnon, N.; Dankort, D.; Piccirillo, C. A.; Journe, F.; Ghanem, G.; Saragovi, H. U.; Sonenberg, N.; Toposiviric, I.; Miller, W. H.; del Rincon, S.
10.1101/2020.05.29.117531 — cancer biology — Posted on 2020-05-30
426 Integrative Molecular Characterization of Sarcomatoid and Rhabdoid Renal Cell Carcinoma Reveals Determinants of Poor Prognosis and Response to Immune Checkpoint Inhibitors
Bakouny, Z.; Braun, D. A.; Shukla, S. A.; Pan, W.; Gao, X.; Hou, Y.; Flaifel, A.; Tang, S.; Bosma-Moody, A.; He, M. X.; Vokes, N.; Nyman, J.; Xie, W.; Nassar, A. H.; Abou Alaiwi, S.; Flippot, R.; Bouchard, G.; Steinharter, J. A.; Nuzzo, P. V.; Ficial, M.; Sant'Angelo, M.; Forman, J.; Berchuck, J. E.; Dudani, S.; Bi, K.; Park, J.; Camp, S.; Sticco-Ivins, M.; Hirsch, L.; Wind-Rotolo, M.; Ross-Macdonald, P.; Sun, M.; Lee, G.-S. M.; Chang, S. L.; Wei, X. X.; McGregor, B. A.; Harshman, L. C.; Genovese, G.; Ellis, L.; Pomerantz, M.; Hirsch, M. S.; Freedman, M. L.; Atkins, M. B.; Wu, C. J.; Ho, T. H.
10.1101/2020.05.28.121806 — cancer biology — Posted on 2020-05-30
427 Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during periods of clinical latency
Werner-Klein, M.; Grujovic, A.; Irlbeck, C.; Obradovic, M.; Hoffmann, M.; Koerkel-Qu, H.; Lu, X.; Treitschke, S.; Koestler, C.; Botteron, C.; Weidele, K.; Werno, C.; Polzer, B.; Kirsch, S.; Guzvic, M.; Warfsmann, J.; Honarnejad, K.; Czyz, Z.; Blochberger, I.; Grunewald, S.; Schneider, E.; Haunschild, G.; Patwary, N.; Guetter, S.; Huber, S.; Buchholz, S.; Ruemmele, P.; Heine, N.; Rose-John, S.; Klein, C. A.
10.1101/2020.05.28.121145 — cancer biology — Posted on 2020-05-30
432 Unscrambling Fluorophore Blinking for Comprehensive Cluster Detection via Photoactivated Localization Microscopy
Platzer, R.; Rossboth, B. K.; Schneider, M. C.; Sevcsik, E.; Baumgart, F.; Stockinger, H.; Schuetz, G. J.; Huppa, J. B.; Brameshuber, M.
10.1101/545152 — biophysics — Posted on 2020-05-30
436 The orchestrated cellular and molecular responses of the kidney to endotoxin define the sepsis timeline
Janosevic, D.; Myslinski, J.; McCarthy, T.; Zollman, A.; Syed, F.; Xuei, X.; Gao, H.; Liu, Y.; Collins, K.; Cheng, Y.-H.; Winfree, S.; El-Achkar, T. M.; Maier, B.; Melo Ferreira, R.; Eadon, M.; Hato, T.; Dagher, P.
10.1101/2020.05.27.118620 — bioinformatics — Posted on 2020-05-30
442 Agile workflow for interactive analysis of mass cytometry data
Casado, J.; Lehtonen, O.; Rantanen, V.; Kaipio, K.; Pasquini, L.; Häkkinen, A.; Petrucci, E.; Carpen, O.; Biffoni, M.; Farkkila, A.; Hautaniemi, S.
10.1101/2020.05.28.120527 — bioinformatics — Posted on 2020-05-30
445 Evolutionary design of optimal surface topographies for biomaterials
Vasilevich, A. S.; Carlier, A.; Winkler, D.; Singh, S. S.; Boer, J. d.
10.1101/2020.05.29.123422 — bioinformatics — Posted on 2020-05-30
449 SPIAT: An R package for the Spatial Image Analysis of Cells in Tissues
Yang, T.; Ozcoban, V.; Pasam, A.; Kocovski, N.; Pizzolla, A.; Huang, Y.-K.; Bass, G.; Keam, S. P.; Neeson, P. J.; Sandhu, S. K.; Goode, D. L.; Trigos, A. S.
10.1101/2020.05.28.122614 — bioinformatics — Posted on 2020-05-30
452 Cellular-scale silicon probes for high-density, precisely-localized neurophysiology
Egert, D.; Pettibone, J. R.; Lemke, S.; Patel, P. R.; Caldwell, C. M.; Cai, D.; Ganguly, K.; Chestek, C. A.; Berke, J.
10.1101/2020.05.26.117572 — bioengineering — Posted on 2020-05-29
453 Injectable hydrogels for sustained co-delivery of subunit vaccines enhance humoral immunity
Roth, G. A.; Gale, E. C.; Alcantara-Hernandez, M.; Luo, W.; Axpe, E.; Smith, A. A. A.; Verma, R.; Yin, Q.; Yu, A. C.; Lopez Hernandez, H.; Maikawa, C. L.; Davis, M. M.; Pulendran, B.; Idoyaga, J.; Appel, E. A.
10.1101/2020.05.26.117465 — bioengineering — Posted on 2020-05-29
455 Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing.
Griffin, D. R.; Archang, M. M.; Kuan, C. H.; Weaver, W.; Weinstein, J. S.; Feng, A. C.; Ruccia, A.; Sideris, E.; Ragkousis, V.; Koh, J.; Plikus, M. V.; Di Carlo, D.; Segura, T.; Scumpia, P. O.
10.1101/2020.05.27.117317 — bioengineering — Posted on 2020-05-30
462 Biofabricating murine and human myo-substitutes for rapid volumetric muscle loss restoration
Costantini, M.; Testa, S.; Fornetti, E.; Fuoco, C.; Nie, M.; Bernardini, S.; Rainer, A.; Baldi, J.; Zoccali, C.; Biagini, R.; Castagnoli, L.; Vitiello, L.; Blaauw, B.; Seliktar, D.; Swieszkowski, W.; Garstecki, P.; Takeuchi, S.; Cesareni, G.; Cannata, S.; Gargioli, C.
10.1101/2020.05.25.114819 — bioengineering — Posted on 2020-05-30
465 Convergent evolution between PALI1 and JARID2 for the allosteric activation of PRC2
Zhang, Q.; Agius, S. C.; Flanigan, S. F.; Levina, V.; Owen, B. M.; Davidovich, C.
10.1101/2020.05.28.122556 — biochemistry — Posted on 2020-05-29
468 CryoEM reveals how the small molecule EGCG binds to AD brain-derived tau fibrils and initiates fibril disaggregation
Seidler, P. M.; Boyer, D. R.; Sawaya, M. R.; Ge, P.; Shin, A.; DeTure, M. A.; Dickson, D. W.; Jiang, L.; Eisenberg, D. S.
10.1101/2020.05.29.124537 — biochemistry — Posted on 2020-05-30
470 The evolution of non-motif selectivity determinants in Monosiga brevicollis PDZ domains
Gao, M.; Mackley, I. G. P.; Mesbahi-Vasey, S.; Bamonte, H. A.; Struyvenberg, S. A.; Landolt, L.; Pederson, N. J.; Williams, L. I.; Bahl, C. D.; Brooks, L.; Amacher, J. F.
10.1101/2020.05.28.121053 — biochemistry — Posted on 2020-05-30
471 A giant leap in sequence space reveals the intracellular complexities of evolving a new function
Hall, K. R.; Robins, K. J.; Rich, M. H.; Calcott, M. J.; Copp, J.; Williams, E. M.; Little, R. F.; Schwörer, R.; Evans, G. B.; Patrick, W. M.; Ackerley, D. F.
10.1101/2020.05.27.118489 — biochemistry — Posted on 2020-05-30
478 2'-O-methylation alters the RNA secondary structural ensemble
Abou Assi, H.; Shi, H.; Liu, B.; Clay, M. C.; Erharter, K.; Kreutz, C.; Holley, C.; Al-Hashimi, H.
10.1101/2020.05.28.121996 — biochemistry — Posted on 2020-05-29
479 Survival on a semi-arid island: submersion and desiccation tolerances of fiddler crabs from the Galapagos Archipelago
capparelli, m. v.; Thurman, C. L.; Abessa, D. M.; Choueri, P. G.; Fontes, M. K.; Nobre, C. R.; McNamara, J. C.
10.1101/2020.05.27.120014 — physiology — Posted on 2020-05-29
480 Chromatin-associated MRN complex protects highly transcribing genes from genomic instability
Salifou, K.; Burnard, C.; Basavarajaiah, P.; Helsmoortel, M.; Mac, V.; Depierre, D.; Grasso, G.; Franckhauser, C.; Beyne, E.; Contreras, X.; Dejardin, J.; Rouquier, S.; Cuvier, O.; Kiernan, R.
10.1101/2020.05.27.118638 — molecular biology — Posted on 2020-05-29
484 The Bgee suite: integrated curated expression atlas and comparative transcriptomics in animals
Bastian, F. B.; Roux, J.; Niknejad, A.; Comte, A.; Fonseca Costa, S. S.; Mendes de Farias, T.; Moretti, S.; Parmentier, G.; Rech de Laval, V.; Rosikiewicz, M.; Wollbrett, J.; Echchiki, A.; Gharib, W.; Gonzales-Porta, M.; Jarosz, Y.; Laurenczy, B.; Moret, P.; Person, E.; Roelli, P.; Sanjeev, K.; Seppey, M.; Robinson-Rechavi, M.
10.1101/2020.05.28.119560 — bioinformatics — Posted on 2020-05-29
487 Immune Response Drives Outcomes in Prostate Cancer: Implications for Immunotherapy
Meng, J.; Zhou, Y.; Lu, X.; Bian, Z.; Chen, Y.; Fan, S.; Zhou, J.; Zhang, L.; Hao, Z.; Zhang, M.; Liang, C.
10.1101/2020.05.26.117218 — immunology — Posted on 2020-05-29
489 ACME dissociation: a versatile cell fixation-dissociation method for single-cell transcriptomics
Garcia-Castro, H.; Kenny, N. J.; Alvarez-Campos, P.; Mason, V.; Schönauer, A.; Sleight, V. A.; Neiro, J.; Aboobaker, A.; Permanyer, J.; Iglesias, M.; Irimia, M.; Sebe-Pedros, A.; Solana, J.
10.1101/2020.05.26.117234 — systems biology — Posted on 2020-05-29
493 Latrophilin-2 repels Teneurin-3+ hippocampal axons during target selection
Pederick, D. T.; Lui, J. H.; Gingrich, E. C.; Xu, C.; Liu, Y.; He, Z.; Quake, S. R.; Luo, L.
10.1101/2020.05.28.122242 — neuroscience — Posted on 2020-05-29
494 CRISPR Knockdown of Kcnq3 Attenuates the M-current in NPY/AgRP Neurons
Stincic, T. L.; Bosch, M. A.; Hunker, A. C.; Juarez, B.; Connors, A. M.; Zweifel, L.; Rønnekleiv, O. K.; Kelly, M. J.
10.1101/2020.05.28.122341 — neuroscience — Posted on 2020-05-29
497 The heart microbiome of insectivorous bats from Central and South Eastern Europe
Corduneanu, A.; Mihalca, A. D.; Sandor, A.; Hornok, S.; Malmberg, M.; PinViso, N.; Bongcam-Rudloff, E.
10.1101/2020.04.30.069815 — microbiology — Posted on 2020-05-29
498 Exploring prokaryotic transcription, operon structures, rRNA maturation and modifications using Nanopore-based native RNA sequencing
Grünberger, F.; Knüppel, R.; Jüttner, M.; Fenk, M.; Borst, A.; Reichelt, R.; Soppa, J.; Ferreira-Cerca, S.; Grohmann, D.
10.1101/2019.12.18.880849 — microbiology — Posted on 2020-05-29
499 Peptide:MHC dependent activation of natural killer cells through KIR2DS2 generates anti-tumor responses
Rettman, P.; Blunt, M. D.; Mbiribindi, B.; Fulton, R.; Schittenhelm, R.; Vallejo, A. F.; Bastidas-Legarda, L.; Polak, M. E.; Ayala, R.; Purcell, A. W. E.; Al-Shamkhani, A.; Retiere, C.; Khakoo, S. I.
10.1101/2020.04.15.042077 — immunology — Posted on 2020-05-29
501 Shared SARS-CoV-2 diversity suggests localised transmission of minority variants
Lythgoe, K. A.; Hall, M. D.; Ferretti, L.; de Cesare, M.; MacIntyre-Cockett, G.; Trebes, A.; Andersson, M.; Otecko, N.; Wise, E. L.; Moore, N.; Lynch, J.; Kidd, S.; Cortes, N.; Mori, M.; Justice, A.; Green, A.; Ansari, M. A.; Abeler-Dorner, L.; Moore, C. E.; Peto, T. E. A.; Shaw, R.; Simmonds, P.; Buck, D.; Todd, J. A.; Bonsall, D.; Fraser, C.; Golubchik, T.
10.1101/2020.05.28.118992 — genomics — Posted on 2020-05-29
504 Chromosight: A computer vision program for pattern detection in chromosome contact maps
Matthey-Doret, C.; Baudry, L.; Breuer, A.; Guiglielmoni, N.; Moreau, P.; Vigouroux, A.; Montagne, R.; Scolari, V.; Politis, L.; Meot, A.; Oriol, E.; Chanut, P.-H.; Campeas, A.; Jean, E.; Koszul, R.; Cournac, A.
10.1101/2020.03.08.981910 — bioinformatics — Posted on 2020-05-29
506 The biofilm matrix scaffold of Pseudomonas species contains non-canonically base paired extracellular DNA and RNA
Seviour, T. W.; Winnerdy, F. R.; Lan Li, W.; Xiangyan, S.; Mugunthan, S.; Castaig, R.; Adav, S. S.; Kohli, G. S.; Shewan, H. M.; Stokes, J.; Rice, S. A.; Phan, A.-T.; Kjelleberg, S.
10.1101/527267 — biochemistry — Posted on 2020-05-29
508 Efficacy of a novel SARS-CoV-2 detection kit without RNA extraction and purification
Fukumoto, T.; Iwasaki, S.; Hayasaka, K.; Sato, K.; Oguri, S.; Taki, K.; Nakakubo, S.; Kamada, K.; Yamashita, Y.; Konno, S.; Nishida, M.; Sugita, J.; Teshima, T.
10.1101/2020.05.27.120410 — microbiology — Posted on 2020-05-29
509 Draft Genome of the Sea Cucumber Holothuria glaberrima, a model for the study of regeneration
Medina-Feliciano, J. G.; Pirro, S.; Garcia-Arraras, J. E.; Mashanov, V.; Ryan, J. F.
10.1101/2020.05.26.117028 — genomics — Posted on 2020-05-29
510 C. elegans establishes germline versus soma by balancing inherited histone methylation
Carpenter, B. S.; Lee, T. W.; Plott, C. F.; Brockett, J. S.; Myrick, D. A.; Katz, D.
10.1101/2020.01.22.914580 — developmental biology — Posted on 2020-05-29
512 Chromatin arranges in chains of mesoscale domains with nanoscale functional topography independent of cohesin
Miron, E.; Oldenkamp, R.; Brown, J. M.; Pinto, D. M.; Xu, C. S.; Faria, A. R.; Shaban, H. A.; Rhodes, J. D.; Innocent, C.; de Ornellas, S.; Hess, H.; Buckle, V.; Schermelleh, L.
10.1101/566638 — genomics — Posted on 2020-05-29
516 Developmental Expression of Transforming Growth Factor Induced Protein Promotes NF-Kappa-B Mediated Angiogenesis During Postnatal Lung Development
Liu, M.; Iosef, C.; Rao, S. P.; Domingo-Gonzalez, R.; Fu, S.; Snider, P.; Conway, S. J.; Umbach, G. S.; Heilshorn, S. C.; Dewi, R. E.; Dahl, M. J.; Null, D. M.; Albertine, K. H.; Alvira, C. M.
10.1101/2020.05.28.121871 — developmental biology — Posted on 2020-05-29
517 Chronic optogenetic stimulation of hippocampal engrams variably modulates social behaviors in mice
Doucette, E.; Leblanc, H.; Monasterio, A.; Cincotta, C.; Grella, S. L.; Logan, J.; Ramirez, S.
10.1101/2020.05.28.121822 — neuroscience — Posted on 2020-05-29
518 Unique maternal immune and functional microbial profiles during prenatal stress
Antonson, A. M.; Evans, M. V.; Galley, J. D.; Chen, H. J.; Rajesekera, T. A.; Lammers, S. M.; Hale, V. L.; Bailey, M. T.; Gur, T. L.
10.1101/2020.05.26.116574 — immunology — Posted on 2020-05-29
520 Cell clusters adopt a collective amoeboid mode of migration in confined non-adhesive environments
Pages, D.-L.; Dornier, E.; de Seze, J.; Wang, L.; Luan, R.; Cartry, J.; Canet-Jourdan, C.; Raingeaud, J.; Voituriez, R.; Coppey, M.; Piel, M.; Jaulin, F.
10.1101/2020.05.28.106203 — cell biology — Posted on 2020-05-29
521 Single Cell Deconstruction of Muscle Stem Cell Heterogeneity During Aging Reveals Sensitivity to the Neuromuscular Junction
Ulintz, P. J.; Larouche, J.; Mohiuddin, M.; Castor Macias, J.; Kurpiers, S. J.; Liu, W.; Choi, J. J.; Brown, L. A.; Markworth, J. F.; de Silva, K.; Levi, B. D.; Merajver, S. D.; Chakkalakal, J. V.; Jang, Y. C.; Brooks, S. V.; Aguilar, C. A.
10.1101/2020.05.28.121426 — cell biology — Posted on 2020-05-29
524 HIV Diversity Considerations in the Application of the Intact Proviral DNA Assay (IPDA)
Kinloch, N. N.; Ren, Y.; Conce Alberto, W. D.; Dong, W.; Khadka, P.; Huang, S. H.; Mota, T. M.; Wilson, A.; Shahid, A.; Kirkby, D.; Harris, M.; Kovacs, C.; Benko, E.; Ostrowski, M. A.; Del Rio Estrada, P. M.; Wimpelberg, A.; Cannon, C.; Hardy, W. D.; MacLaren, L.; Goldstein, H.; Brumme, C. J.; Lee, G. Q.; Lynch, R. M.; Brumme, Z. L.; Jones, R. B.
10.1101/2020.05.26.115006 — genetics — Posted on 2020-05-29
526 Targeted disruption of Pparγ1 promotes trophoblast endoreplication in the murine placenta
Nakano, T.; Aochi, H.; Hirasaki, M.; Takenaka, Y.; Fujita, K.; Soma, H.; Kamezawa, H.; Koizumi, T.; Okuda, A.; Murakoshi, T.; Shimada, A.; Inoue, I.
10.1101/2020.05.28.120691 — developmental biology — Posted on 2020-05-29
529 Sox9EGFP defines biliary epithelial heterogeneity downstream of Yap activity
Tulasi, D. Y.; Martinez Castaneda, D.; Wager, K. E.; Alcedo, K. P.; Raab, J. R.; Gracz, A. D.
10.1101/2020.05.28.113522 — cell biology — Posted on 2020-05-29
530 Sustained Androgen Receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis
Ma, M.; Ghosh, S.; Tavernari, D.; Katarkar, A.; Clocchiatti, A.; Mazzeo, L.; Samarkina, A.; Epiney, J.; Yu, Y.-R.; Ho, P.-C.; Levesque, M. P.; Özdemir, B.; Ciriello, G.; Dumme, R.; Dotto, G.-P.
10.1101/2020.05.26.116665 — cancer biology — Posted on 2020-05-29
531 Assessment of Inactivation Procedures for SARS-CoV-2
Auerswald, H.; Yann, S.; Dul, S.; In, S.; Dussart, P.; Martin, N. J.; Karlsson, E. A.; Garcia-Rivera, J. A.
10.1101/2020.05.28.120444 — microbiology — Posted on 2020-05-28
532 Burkholderia thailandensis methylated hydroxy-alkylquinolines: biosynthesis and antimicrobial activity in co-culture experiments
Klaus, J. R.; Majerczyk, C.; Eppler, N. A.; Ball, P.; Groleau, M.-C.; Asfahl, K. L.; Smalley, N. E.; Hayden, H.; Piochon, M.; Dandekar, A. A.; Gauthier, C.; Deziel, E.; Chandler, J. R.
10.1101/2020.05.27.120295 — microbiology — Posted on 2020-05-28
533 Non-Invasive Single-Cell Morphometry in Living Bacterial Biofilms
Zhang, M.; Zhang, J.; Wang, Y.; Wang, J.; Achimovich, A. M.; Acton, S. T.; Gahlmann, A.
10.1101/2020.05.28.120279 — microbiology — Posted on 2020-05-28
536 Comprehensive Transcriptomic Analysis of COVID-19 Blood, Lung, and Airway
Daamen, A. R.; Bachali, P.; Owen, K. A.; Kingsmore, K. M.; Hubbard, E. L.; Labonte, A. C.; Robl, R.; Shrotri, S.; Grammer, A. C.; Lipsky, P. E.
10.1101/2020.05.28.121889 — immunology — Posted on 2020-05-28
537 Advancing the genetic utility of pre-clinical species through a high-quality assembly of the cynomolgus monkey (Macaca fascicularis) genome
Oziolor, E. M.; Sullivan, S.; Mangelson, H.; Eacker, S. M.; Agostino, M.; Whiteley, L. O.; Cook, J.; Koza-Taylor, P.
10.1101/2020.05.01.072280 — genomics — Posted on 2020-05-29
540 Semi-automatic stitching of filamentous structures in image stacks from serial-section electron tomography
Baum, D.; Lindow, N.; Brünig, F. N.; Dercksen, V. J.; Fabig, G.; Kiewisz, R.; Redemann, S.; Müller-Reichert, T.; Prohaska, S.
10.1101/2020.05.28.120899 — cell biology — Posted on 2020-05-28
545 NF45/NF90-mediated rDNA transcription provides a novel target for immunosuppressant development
Hsiang-i, T.; Zeng, X.; Liu, L.; Xin, S.; Wu, Y.; Xu, Z.; Liu, G.; Bi, Z.; Su, D.; Yang, M.; Wang, C.; Zhao, J.; Eriksson, J. E.; Deng, W.; Cheng, F.; Chen, H.
10.1101/2020.05.26.116897 — molecular biology — Posted on 2020-05-28
546 Genotypic diversity between surgical and nasal Staphylococcus aureus isolates
Ma, D.; Maher, P. L.; Brothers, K. M.; Phillips, J. E.; Simonetti, D.; Pasculle, A. W.; Richardson, A. R.; Cooper, V. S.; Urish, K. L.
10.1101/2020.05.27.120436 — microbiology — Posted on 2020-05-28
549 Regulation of blood cell transdifferentiation by oxygen sensing neurons in Drosophila
Corcoran, S.; Mase, A.; Hashmi, Y.; Ouyang, D.; Augsburger, J.; Jacobs, T.; Kukar, K.; Brueckner, K.
10.1101/2020.04.22.056622 — developmental biology — Posted on 2020-05-28
555 Bilayer graphene oxide membranes for a wearable hemodialyzer
Rode, R.; Chung, H.; Miller, H.; Gaborski, T. R.; Moghaddam, S.
10.1101/2020.05.26.116863 — bioengineering — Posted on 2020-05-28
556 Optimizing high-yield production of SARS-CoV-2 soluble spike trimers for serology assays
Esposito, D.; Mehalko, J.; Drew, M.; Snead, K.; Wall, V.; Taylor, T.; Frank, P.; Denson, J.-P.; Hong, M.; Gulten, G.; Sadtler, K.; Messing, S.; Gillette, W.
10.1101/2020.05.27.120204 — biochemistry — Posted on 2020-05-28
557 "Monoclonal-type" plastic antibodies for SARS-CoV-2 based on Molecularly Imprinted Polymers
Puoci, F.; Parisi, O. I.; Dattilo, M.; Patitucci, F.; Malivindi, R.; Pezzi, V.; Perrotta, I.; Ruffo, M.; Amone, F.
10.1101/2020.05.28.120709 — synthetic biology — Posted on 2020-05-28
558 Characterization of Components of Resistance to Corn Stunt Disease
Oleszczuk, J. D.; Catalano, M. I.; Dalaison, L.; Di Rienzo, J. A.; Gimenez Pecci, M. d. l. P.; Carpane, P.
10.1101/2020.05.28.120972 — plant biology — Posted on 2020-05-28
562 Monitoring the microbiome for food safety and quality using deep shotgun sequencing
Beck, K. L.; Haiminen, N.; Chambliss, D.; Edlund, S. B.; Kunitomi, M.; Huang, B. C.; Kong, N.; Ganesan, B.; Baker, R.; Markwell, P.; Kawas, B.; Davis, M.; Prill, R. J.; Krishnareddy, H.; Seabolt, E.; Marlowe, C. H.; Pierre, S.; Quintanar, A.; Parida, L.; Dubois, G.; Kaufman, J.; Weimer, B. C.; Consortium for Sequencing the Food Supply Chain,
10.1101/2020.05.18.102574 — microbiology — Posted on 2020-05-28
564 Fecal microbiota transplantation efficacy for Clostridium difficile infection: A trans-kingdom battle between donor and recipient gut microbiomes
Kazemian, N.; Ramezankhani, M.; Sehgal, A.; Khalid, F. M.; Kalkhoran, A. H. Z.; Narayan, A.; Wong, G. K.-S.; Kao, D.; Pakpour, S.
10.1101/2020.05.27.120386 — microbiology — Posted on 2020-05-28
565 Single-dose replicating RNA vaccine induces neutralizing antibodies against SARS-CoV-2 in nonhuman primates
Erasmus, J. H.; Khandhar, A. P.; Walls, A. C.; Hemann, E. A.; O'Connor, M. A.; Murapa, P.; Archer, J.; Leventhal, S.; Fuller, J.; Lewis, T.; Draves, K. E.; Randall, S.; Guerriero, K. A.; Duthie, M. S.; Carter, D.; Reed, S. G.; Hawman, D. W.; Feldmann, H.; Gale, M.; Veesler, D.; Berglund, P.; Fuller, D. H.
10.1101/2020.05.28.121640 — immunology — Posted on 2020-05-28
566 Developmentally Delayed Epigenetic Reprogramming Underlying the Pathogenesis of Preeclampsia
He, W.; Wei, Y.; Gong, X.; Chang, L.; Jin, W.; Liu, K.; Wang, X.; Xiao, Y.; Zhang, W.; Chen, Q.; Wu, K.; Liang, L.; Liu, J.; Chen, Y.; Guo, H.; Li, X.; Chen, W.; Yang, J.; Qi, Y.; Dong, W.; Fu, M.; Liu, J.; Zhang, Y.; Yin, A.
10.1101/2020.05.08.085290 — genomics — Posted on 2020-05-28
568 LincRNA sequences are biased to counteract their translation
Brümmer, A.; Dreos, R.; Marques, A. C.; Bergmann, S.
10.1101/737890 — genomics — Posted on 2020-05-28
569 SARS-CoV-2 genomics beyond the consensus sequence: evidence for circulating mixed viral populations
Lythgoe, K. A.; Hall, M. D.; Ferretti, L.; de Cesare, M.; MacIntyre-Cockett, G.; Trebes, A.; Andersson, M.; Otecko, N.; Wise, E. L.; Moore, N.; Lynch, J.; Kidd, S.; Cortes, N.; Mori, M.; Justice, A.; Green, A.; Ansari, M. A.; Abeler-Dorner, L.; Moore, C. E.; Peto, T. E. A.; Shaw, R.; Simmonds, P.; Buck, D.; Todd, J. A.; Bonsall, D.; Fraser, C.; Golubchik, T.
10.1101/2020.05.28.118992 — genomics — Posted on 2020-05-28
571 Evidence for two main domestication trajectories in Saccharomyces cerevisiae linked to distinct bread-making processes
Bigey, F.; Segond, D.; Friedrich, A.; Guezenec, S.; Bourgais, A.; Huyghe, L.; Agier, N.; Nidelet, T.; Sicard, D.
10.1101/2020.05.28.120584 — genomics — Posted on 2020-05-28
581 Integrated sample inactivation, amplification, and Cas13-based detection of SARS-CoV-2
Arizti-Sanz, J.; Freije, C. A.; Stanton, A. C.; Boehm, C. K.; Petros, B. A.; Siddiqui, S.; Shaw, B. M.; Adams, G.; Kosoko-Thoroddsen, T.-S. F.; Kemball, M. E.; Gross, R.; Wronka, L.; Caviness, K.; Hensley, L. E.; Bergman, N. H.; MacInnis, B. L.; Lemieux, J. E.; Sabeti, P. C.; Myhrvold, C.
10.1101/2020.05.28.119131 — bioengineering — Posted on 2020-05-28
584 A single-cell transcriptomic and anatomic atlas of mouse dorsal raphe Pet1 neurons
Okaty, B. W.; Sturrock, N.; Escobedo Lozoya, Y.; Chang, Y.; Senft, R. A.; Lyon, K. A.; Alekseyenko, O. V.; Dymecki, S. M.
10.1101/2020.01.28.923375 — neuroscience — Posted on 2020-05-28
585 Evolutionary stasis of the pseudoautosomal boundary in strepsirrhine primates
Shearn, R.; Wright, A.; Mousset, S.; Regis, C.; Penel, S.; Lemaitre, J. F.; Douay, G.; Crouau-Roy, B.; Lecompte, E.; Marais, G.
10.1101/445072 — evolutionary biology — Posted on 2020-05-28
586 In vivo deuterated water labeling allows tumor visualization via deuterium magnetic resonance spectroscopic imaging of cholesterol
Assmann, J. C.; Brender, J. R.; Farthing, D. E.; Saito, K.; Warrick, K. A.; Maglakelidze, N.; Crooks, D. R.; Merkle, H.; Krishna, M. C.; Gress, R. E.; Buxbaum, N. P.
10.1101/809327 — cancer biology — Posted on 2020-05-28
592 The Axenfeld-Rieger syndrome gene FOXC1 contributes to left-right patterning
Chrystal, P. W.; French, C. R.; Jean, F.; Havrylov, S.; van Baarle, S.; Peturson, A.-M.; Xu, P.; Crump, J. G.; Pilgrim, D. B.; Lehmann, O. J.; Waskiewicz, A. J.
10.1101/2020.05.28.120915 — genetics — Posted on 2020-05-28
593 The 20S proteasome activator PA28γ controls the compaction of chromatin
Fesquet, D.; Lleres, D.; Grimaud, C.; Vigano, C.; Mechali, F.; Boulon, S.; Feil, R.; Coux, O.; Bonne-Andrea, C.; Baldin, V.
10.1101/716332 — cell biology — Posted on 2020-05-28
596 Restructuring of amygdala subregion apportion across adolescence
Campbell, C. E.; Mezher, A. F.; Eckel, S. P.; Tyszka, J. M.; Pauli, W. M.; Nagel, B. J.; Herting, M. M.
10.1101/690875 — neuroscience — Posted on 2020-05-28
597 The dynamics of spawning acts by a semelparous fish and its associated energetic expenses
Tentelier, C.; Bouchard, C.; Bernardin, A.; Tauzin, A.; Aymes, J.-C.; Lange, F.; Recapet, C.; Rives, J.
10.1101/436295 — ecology — Posted on 2020-05-28
601 Multicellular rosettes organize neuropil formation
Brittin, C. A.; Santella, A.; Barnes, K. M.; Moyle, M. W.; Fan, L.; Christensen, R.; Kolotuev, I.; Mohler, W. A.; Schroff, H.; Colón-Ramos, D.; Bao, Z.
10.1101/2020.05.27.119750 — neuroscience — Posted on 2020-05-28
606 Sponges as bioindicators for microparticulate pollutants
Girard, E. B.; Fuchs, A.; Kaliwoda, M.; Lasut, M.; Ploetz, E.; Schmahl, W. W.; Wörheide, G.
10.1101/2020.05.26.116012 — ecology — Posted on 2020-05-28
607 Prediction of vascular ageing based on smartphone acquired PPG signals
Dall'Olio, L.; Curti, N.; Remondini, D.; Harb, Y. S.; Asselbergs, F. W.; Castellani, G.; Uh, H.-W.
10.1101/2020.05.26.116186 — biophysics — Posted on 2020-05-28
613 Conserved nicotine-activated neuroprotective pathways involve mitochondrial stress
Nourse, B. J.; Harshefi, G.; Marom, A.; Karmi, A.; Caldwell, K. A.; Caldwell, G. A.; Treinin, M.
10.1101/2020.05.28.120576 — neuroscience — Posted on 2020-05-28
614 Atoh7-independent specification of retinal ganglion cell identity
Brodie-Kommit, J.; Hattar, S.; Clark, B. S.; Shi, Q.; Shiau, F.; Kim, D. W.; Langel, J.; Sheely, C.; Schmidt, T. M.; Glaser, T.; Badea, T.; Zhao, H.; Singer, J. H.; Blackshaw, S.
10.1101/2020.05.27.116954 — developmental biology — Posted on 2020-05-28
615 Exposure to hypergravity during development leads to altered cartilage material properties and strain distribution in zebrafish.
Lawrence, E. A.; Aggleton, J. A.; van Loon, J. J. W. A.; Godivier, J.; Harniman, R. L.; Pei, J.; Nolan, N. C.; Hammond, C. L.
10.1101/2020.05.26.116046 — physiology — Posted on 2020-05-28
618 "Select and retrieve via direct upsampling" network (SARDU-Net): a data-driven, model-free, deep learning approach for quantitative MRI protocol design
Grussu, F.; Blumberg, S. B.; Battiston, M.; Kakkar, L. S.; Lin, H.; Ianus, A.; Schneider, T.; Singh, S.; Bourne, R.; Punwani, S.; Atkinson, D.; Gandini Wheeler-kingshott, C. A. M.; Panagiotaki, E.; Mertzanidou, T.; Alexander, D. C.
10.1101/2020.05.26.116491 — bioengineering — Posted on 2020-05-28
619 Combinatorial Polyacrylamide Hydrogels for Preventing Biofouling on Implantable Biosensors
Chan, D.; Chien, J.-C.; Axpe, E.; Blankemeier, L.; Baker, S. W.; Swaminathan, S.; Piunova, V. A.; Zubarev, D. Y.; Soh, H. T.; Appel, E. A.
10.1101/2020.05.25.115675 — bioengineering — Posted on 2020-05-28
622 Keratin 19 maintains E-cadherin localization at the cell surface and stabilizes cell-cell adhesion of MCF7 cells
Alsharif, S.; Sharma, P.; Bursch, K.; Milliken, R.; Collins, M.; Lam, V.; Fallatah, A.; Phan, T.; Dohlman, P.; Nehmetallah, G.; Raub, C. B.; Chung, B. M.
10.1101/2020.05.28.119297 — cell biology — Posted on 2020-05-28
624 Templating S100A9 amyloids on Aβ fibrillar surfaces revealed by charge detection mass spectrometry, microscopy, kinetic and microfluidic analyses
Pansieri, J.; Iashchishyn, I. A.; Fakhouri, H.; Ostojic, L.; Malisauskas, M.; Musteikyte, G.; Smirnovas, V.; Schneider, M. M.; Scheidt, T.; Xu, C. K.; Meisl, G.; Knowles, T. P.; Gazit, E.; Antoine, R.; Morozova-Roche, L.
10.1101/2020.05.26.116400 — biophysics — Posted on 2020-05-28
627 Atypical B cells are a normal component of immune responses to vaccination and infection in humans
Sutton, H. J.; Aye, R.; Idris, A. H.; Vistein, R.; Nduati, E.; Kai, O.; Mwacharo, J.; Xi, L.; Gao, X.; Andrews, D.; Koutsakos, M.; Nguyen, T. H. O.; Nekrasov, M.; Milburn, P.; Ethala, A.; Berry, A. A.; KC, N.; Chakravarty, S.; Sim, B. K. L.; Wheatley, A. K.; Kent, S. J.; Hoffman, S. L.; Lyke, K. E.; Bejon, P.; Luciani, F.; Kedzierska, K.; Seder, R. A.; Ndungu, F. M.; Cockburn, I. A.
10.1101/2020.05.28.120808 — immunology — Posted on 2020-05-28
629 Novel heme-binding enables allosteric modulation in an ancient TIM-barrel glycosidase
Gamiz-Arco, G.; Gutierrez-Rus, L.; Risso, V.; Ibarra-Molero, B.; Hoshino, Y.; Petrovic, D.; Romero-Rivera, A.; Seelig, B.; Gavira, J.; Kamerlin, S.; Gaucher, E.; Sanchez-Ruiz, J.
10.1101/2020.05.27.118968 — biophysics — Posted on 2020-05-28
632 Mechanistic insights into ventricular arrhythmogenesis of hydroxychloroquine and azithromycin for the treatment of COVID-19
Wang, G.; Tian, X.; Lu, C.-J.; Flores, H.; Maj, P.; Zhang, K.; Niu, Y.; Wang, L.; Du, Y.; Ji, X.; Xu, Y.; Trafford, A.; Li, D.; Herring, N.; Paterson, D.; Huang, C.; Zhang, H.; Lei, M.; Hao, G.
10.1101/2020.05.21.108605 — pharmacology and toxicology — Posted on 2020-05-28
633 The SARS-CoV-2 cytopathic effect is blocked with autophagy modulators
Gorshkov, K.; Chen, C. Z.; Bostwick, R.; Rasmussen, L.; Xu, M.; Pradhan, M.; Tran, B. N.; Zhu, W.; Shamim, K.; Huang, W.; Hu, X.; Shen, M.; Klumpp-Thomas, C.; Itkin, Z.; Shinn, P.; Simeonov, A.; Michael, S.; Hall, M. D.; Lo, D. C.; Zheng, W.
10.1101/2020.05.16.091520 — pharmacology and toxicology — Posted on 2020-05-28
635 Multi-contrast Anatomical Subcortical Structures Parcellation
Bazin, P.-L.; Alkemade, A.; Mulder, M.; Henry, A. G.; Forstmann, B.
10.1101/2020.05.26.115865 — neuroscience — Posted on 2020-05-28
636 Conscious processing of narrative stimuli synchronizes heart rate between individuals
Perez, P.; Madsen, J.; Banellis, L.; Turker, B.; Raimondo, F.; Perlbarg, V.; Valente, M.; Nierat, M.-C.; Puybasset, L.; Naccache, L.; Similowski, T.; Cruse, D.; Parra, L. C.; SITT, J.
10.1101/2020.05.26.116079 — neuroscience — Posted on 2020-05-28
638 Fear learning sculpts functional brain connectivity at rest beyond the traditional fear network in humans
Fraenz, C.; Metzen, D.; Merz, C. J.; Selpien, H.; Friedrich, P.; Ocklenburg, S.; Axmacher, N.; Genc, E.
10.1101/2020.05.26.115840 — neuroscience — Posted on 2020-05-28
641 Chromatin-associated protein complexes link DNA base J and transcription termination in Leishmania
Jensen, B. C.; Phan, I. Q.; McDonald, J. R.; Sur, A.; Gillespie, M. A.; Ranish, J. A.; Parsons, M.; Myler, P. J.
10.1101/2020.05.26.117721 — molecular biology — Posted on 2020-05-28
642 Ozone Treatment for Elimination of Bacteria and SARS-CoV2 for Medical Environments
Westover, C.; Rahmatulloev, S.; Danko, D.; Afshinnekoo, E.; O'Hara, N. B.; Ounit, R.; Bezdan, D.; Mason, C. E.
10.1101/420737 — microbiology — Posted on 2020-05-28
643 Human IgG neutralizing monoclonal antibodies block SARS-CoV-2 infection
Wan, J.; Xing, S.; Ding, L.; Wang, Y.; Zhu, D.; Rong, B.; Wang, S.; Chen, K.; He, C.; Yuan, S.; Qiu, C.; Zhao, C.; Zhang, X.; Wang, X.; Lu, Y.; Xu, J.; Lan, F.
10.1101/2020.05.19.104117 — immunology — Posted on 2020-05-28
644 A validation of Illumina EPIC array system with bisulfite-based amplicon sequencing
Noble, A. J.; Pearson, J. F.; Boden, J. M.; Horwood, L. J.; Gemmell, N. J.; Kennedy, M. A.; Osborne, A. J.
10.1101/2020.05.25.115428 — genomics — Posted on 2020-05-28
645 Genetic, lifestyle and environmental risk factors for chronic pain revealed through GWAS
Lundberg, M.; Campos Gonzalez, A. I.; Farrell, S. F.; Wang, G.; Sterling, M.; Renteria, M. E.; Ngo, T. T.; Cuellar Partida, G.
10.1101/2020.05.26.115568 — genetics — Posted on 2020-05-28
646 Lifestyle Risk Score for aggregating multiple lifestyle factors: Handling missingness of individual lifestyle components in meta-analysis of gene-by-lifestyle interactions
Xu, H.; Schwander, K.; Brown, M. R.; Wang, W.; Waken, R.; Boerwinkle, E.; Cupples, L. A.; de las Fuentes, L.; van Heemst, D.; Osazuwa-Peters, O.; de Vries, P. S.; van Dijk, K. W.; Sung, Y. J.; Zhang, X.; Morrison, A. C.; Rao, D.; Noordam, R.; Liu, C.-T.
10.1101/2020.05.26.116723 — genetics — Posted on 2020-05-28
647 Benefit of Drought on an Herbivore of Herbaceous Plants: Enemy Free Space and Reduced Competition
Lin, P.-A.; Liu, C.-M.; Ou, J.-A.; Sun, C.-H.; Chuang, W.-P.; Ho, C.-K.; Kinoshita, N.; Felton, G. W.
10.1101/2020.05.25.115519 — ecology — Posted on 2020-05-28
651 Real-space quantum-based refinement for cryo-EM: Q|R#3
Wang, L.; Kruse, H.; Sobolev, O. V.; Moriarty, N. W.; Waller, M. P.; Afonine, P. V.; Biczysko, M.
10.1101/2020.05.25.115386 — bioinformatics — Posted on 2020-05-28
652 SARS-CoV-2 mutations and where to find them: An in silico perspective of structural changes and antigenicity of the Spike protein
Lemes Goncalves, R.; Leite, T. C. R.; Dias, B. d. P.; Caetano, C. C. d. S.; Souza, A. C. G. d.; Batista, U. d. S.; Barbosa, C. C.; Reyes-Sandoval, A.; Leomil Coelho, L. F.; Silva, B. d. M.
10.1101/2020.05.21.108563 — bioinformatics — Posted on 2020-05-28
653 Insurgence and worldwide diffusion of genomic variants in SARS-CoV-2 genomes
Comandatore, F.; Chiodi, A.; Gabrieli, P.; Batisti Biffignandi, G.; Perini, M.; Ricagno, S.; Mascolo, E.; Petazzoni, G.; Ramazzotti, M.; Rimoldi, S. G.; Gismondo, M.; Micheli, V.; Sassera, D.; Gaiarsa, S.; Bandi, C.; Brilli, M.
10.1101/2020.04.30.071027 — bioinformatics — Posted on 2020-05-28
654 Characterization of systemic genomic instability in budding yeast
Vieira Sampaio, N. M.; Ajith, V. P.; Watson, R. A.; Heasley, L. R.; Chakraborty, P.; Rodrigues-Prause, A.; Malc, E. P.; Mieczkowski, P. A.; Nishant, K. T.; Argueso, J. L.
10.1101/2020.05.25.115535 — genetics — Posted on 2020-05-28
656 Miniaturized head-mounted device for whole cortex mesoscale imaging in freely behaving mice
Rynes, M. L.; Surinach, D.; Linn, S.; Laroque, M.; Rajendran, V.; Dominguez, J.; Hadjistamolou, O.; Navabi, Z. S.; Ghanbari, L.; Johnson, G. L.; Nazari, M.; Mohajerani, M.; Kodandaramaiah, S. B.
10.1101/2020.05.25.114892 — neuroscience — Posted on 2020-05-28
658 Neutrophils Mediate Kidney Inflammation Following Acute Skin Exposure to UVB Light
Skopelja-Gardner, S.; Tai, J.; Sun, X.; Tanaka, L.; Kuchenbecker, J. A.; Snyder, J. M.; Kubes, P.; Mustelin, T.; Elkon, K. B.
10.1101/2020.05.25.115204 — immunology — Posted on 2020-05-28
659 DNA polymerase epsilon is a central coordinator of heterochromatin structure and function in Arabidopsis
Bourguet, P.; Lopez-Gonzalez, L.; Gomez-Zambrano, A.; Pelissier, T.; Hesketh, A.; Potok, M. E.; Pouch-Pelissier, M.-N.; Perez, M.; Da Ines, O.; Latrasse, D.; White, C. I.; Jacobsen, S. E.; Benhamed, M.; Mathieu, O.
10.1101/2020.05.26.117556 — genomics — Posted on 2020-05-28
663 Fast in vivo 23Na imaging and T2* mapping using accelerated 2D-FID magnetic resonance spectroscopic imaging at 3 T: Proof of concept and reliability study
Alhulail, A. A.; Xia, P.; Shen, X.; Nichols, M.; Volety, S.; Farley, N.; Thomas, M. A.; Nagel, A. M.; Dydak, U.; Emir, U. E.
10.1101/2020.05.25.114918 — biophysics — Posted on 2020-05-28
664 Male-mediated maturation in a wild primate
Lu, A.; Feder, J. A.; Snyder-Mackler, N.; Bergman, T. J.; Beehner, J. C.
10.1101/2020.05.25.114934 — zoology — Posted on 2020-05-28
665 Development of genetic markers for sexing Cannabis sativa seedlings
Prentout, D.; Razumova, O.; Henri, H.; Divashuk, M.; Karlov, G.; Marais, G. A.
10.1101/2020.05.25.114355 — plant biology — Posted on 2020-05-28
667 Inversion Genotyping in the Anopheles gambiae Complex Using High-Throughput Array and Sequencing Platforms
Love, R. R.; Pombi, M.; Guelbeogo, M. W.; Campbell, N. R.; Stephens, M. T.; Dabire, R. K.; Costantini, C.; della Torre, A.; Besansky, N. J.
10.1101/2020.05.25.114793 — genomics — Posted on 2020-05-28
670 Reference genome and demographic history of the most endangered marine mammal, the vaquita
Morin, P. A.; Archer, F. I.; Avila, C. D.; Balacco, J. R.; Bukhman, Y. V.; Chow, W.; Fedrigo, O.; Formenti, G.; Fronczek, J. A.; Fungtammasan, A.; Gulland, F. M. D.; Haase, B.; Heide-Jorgensen, M. P.; Houck, M.; Howe, K.; Misuraca, A. C.; Mountcastle, J.; Musser, W.; Paez, S.; Pelan, S.; Phillippy, A. M.; Rhie, A.; Robinson, J. A.; Rojas-Bracho, L.; Rowles, T. K.; Ryder, O. A.; Smith, C. R.; Stevenson, S.; Taylor, B. L.; Teilmann, J.; Torrance, J.; Wells, R. S.; Westgate, A.; Jarvis, E.
10.1101/2020.05.27.098582 — genomics — Posted on 2020-05-28
674 Defining the familial fold of the vicilin-buried peptide family
Payne, C. D.; Vadlamani, G.; Fisher, M. F.; Zhang, J.; Clark, R. J.; Mylne, J. S.; Rosengren, K. J.
10.1101/2020.05.26.118075 — biochemistry — Posted on 2020-05-28
675 Molecular connection between the TUTase URT1 and decapping activators
Scheer, H.; de Almeida, C.; Ferrier, E.; Poirier, L.; Pflieger, D.; Sement, F. M.; Koechler, S.; Piermaria, C.; Chicher, J.; Kuhn, L.; Hammann, P.; Zuber, H.; Gagliardi, D.
10.1101/2020.05.26.114322 — molecular biology — Posted on 2020-05-28
676 TRACE-Seq Reveals Clonal Reconstitution Dynamics of Gene Targeted Human Hematopoietic Stem Cells
Sharma, R.; Dever, D. P.; Lee, C. M.; Azizi, A.; Pan, Y.; Camarena, J.; Köhnke, T.; Bao, G.; Porteus, M.; Majeti, R.
10.1101/2020.05.25.115329 — molecular biology — Posted on 2020-05-28
677 Light-Sheet Fluorescence Imaging Charts the Gastrula Origin of Vascular Endothelial Cells in Early Zebrafish Embryos
Xiong, J.-W.; Pang, M.; Bai, L.; Zong, W.; Wang, X.; Bu, Y.; Xiong, C.; Zheng, J.; Li, J.; Gao, W.; Feng, Z.; Chen, L.; Zhang, J.; Cheng, H.; Zhu, X.
10.1101/2020.05.27.118661 — developmental biology — Posted on 2020-05-28
679 Essential amnion signals for primate primitive streak formation resolved by scRNA map
Yang, R.; Goedel, A.; Kang, Y.; Si, C.; Chu, C.; Zheng, Y.; Chen, Z.; Gruber, P. J.; Xiao, Y.; Zhou, C.; Leung, C.-Y.; Chen, Y.; Fu, J.; Ji, W.; Lanner, F.; Niu, Y.; Chien, K. R.
10.1101/2020.05.28.118703 — developmental biology — Posted on 2020-05-28
683 Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology
Stangherlin, A.; Wong, D. C. S.; Barbiero, S.; Watson, J. L.; Zeng, A.; Seinkmane, E.; Chew, S. P.; Beale, A. D.; Hayter, E. A.; Guna, A.; Inglis, A.; Bartolami, E.; Matile, S.; Lequeux, N.; Pons, T.; Day, J.; van Ooijen, G.; Voorhees, R. M.; Bechtold, D.; Derivery, E.; Edgar, R. S.; Newham, P.; O'Neill, J. S.
10.1101/2020.05.28.118398 — cell biology — Posted on 2020-05-28
684 Novel antioxidant therapy with the immediate precursor to glutathione, γ-glutamylcysteine (GGC), ameliorates LPS-induced cellular stress in an in vitro cystic fibrosis model
Hewson, C. K.; Capraro, A.; Wong, S. L.; Pandzic, E.; Fernando, B. S. M.; Awatade, N. T.; Zhong, L.; Hart-Smith, G.; Whan, R. M.; Thomas, S. R.; Jaffe, A.; Bridge, W. J.; Waters, S. A.
10.1101/2020.05.27.119990 — cell biology — Posted on 2020-05-28
687 Single cell analysis of human site-specific melanocyte differentiation and the decoding of developmental programs in melanoma
Belote, R. L.; Le, D.; Maynard, A.; Lang, U. E.; Sinclair, A.; Planells-Palop, V.; Baskin, L. S.; Tward, A. D.; Darmanis, S.; Judson-Torres, R. L.
10.1101/2020.05.25.115287 — cancer biology — Posted on 2020-05-28
688 Anaphase Promoting Complex activity mediates clinical responsiveness to recurrent caninelymphoma
Aranson, T.; MacDonald-Dickinson, V.; Davies, G. F.; Gaunt, C.; Lubanova, L.; Trost, B.; Waldner, M.; Baldwin, P.; Borrowood, D.; Marwood, H.; Gillespie, Z. E.; Vizeacoumar, F.; Vizeacoumar, F.; Eskiw, C. H.; Kusalik, A.; Harkness, T. A. A.
10.1101/2020.05.26.115337 — cancer biology — Posted on 2020-05-28
690 Cryo-EM Structure of Native Human Uromodulin, a Zona Pellucida Module Polymer
Stsiapanava, A.; Xu, C.; Brunati, M.; Zamora-Caballero, S.; Schaeffer, C.; Han, L.; Carroni, M.; Yasumasu, S.; Rampoldi, L.; Wu, B.; Jovine, L.
10.1101/2020.05.28.119206 — biophysics — Posted on 2020-05-28
691 The linear ubiquitin chain assembly complex generates heterotypic ubiquitin chains
Carvajal, A. R.; Diaz, C. G.; Vogel, A.; Sonn-Segev, A.; Schodl, K.; Deszcz, L.; Orban-Nemeth, Z.; Sakamoto, S.; Mechtler, K.; Kukura, P.; Clausen, T.; Haselbach, D.; Ikeda, F.
10.1101/2020.05.27.117952 — biochemistry — Posted on 2020-05-28
695 Sex-biased reduction in reproductive success drives selective constraint on human genes
Gardner, E. J.; Neville, M. D.; Samocha, K. E.; Barclay, K.; Kolk, M.; Niemi, M. E.; Kirov, G.; Martin, H. C.; Hurles, M. E.
10.1101/2020.05.26.116111 — genetics — Posted on 2020-05-28
696 The island rule explains consistent patterns of body size evolution across terrestrial vertebrates
Benitez-Lopez, A.; Santini, L.; Gallego-Zamorano, J.; Mila, B.; Walkden, P.; Huijbregts, M. A. J.; Tobias, J. A.
10.1101/2020.05.25.114835 — ecology — Posted on 2020-05-28
697 Tumor-on-a-chip platform to interrogate the role of macrophages in tumor progression
Bi, Y.; Shirure, V. S.; Liu, R.; Cunningham, C.; Ding, L.; Meacham, M.; Goedegebuure, P.; George, S. C.; Fields, R. C.
10.1101/2020.05.27.119636 — cancer biology — Posted on 2020-05-28
698 Single cell characterization of B-lymphoid differentiation and leukemic cell states during chemotherapy in ETV6-RUNX1 positive pediatric leukemia identifies drug-targetable transcription factor activities
Mehtonen, J.; Teppo, S.; Lahnalampi, M.; Kokko, A.; Kaukonen, R.; Oksa, L.; Bouvy-Liivrand, M.; Malyukova, A.; Laukkanen, S.; Makinen, P. I.; Rounioja, S.; Ruusuvuori, P.; Sangfelt, O.; Lund, R.; Lonnberg, T.; Lohi, O.; Heinaniemi, M.
10.1101/2020.05.27.116293 — cancer biology — Posted on 2020-05-28
700 The histone demethylase KDM6B fine-tunes the host response to Streptococcus pneumoniae.
Connor, M. G.; Camarasa, T. M. N.; Patey, E.; Rasid, O.; Barrio, L.; Weight, C.; Miller, D. P.; HEYDERMAN, R. S.; Lamont, R. J.; Enninga, J.; Hamon, M. A.
10.1101/757906 — microbiology — Posted on 2020-05-28
704 Macromolecular and electrical coupling between inner hair cells in the rodent cochlea
Jean, P.; Anttonen, T.; Michanski, S.; Garcia de Diego, A. M.; Steyer, A. M.; Neef, A.; Oestreicher, D.; Kroll, J.; Nardis, C.; Pangrsic, T.; Moebius, W.; Ashmore, J.; Wichmann, C.; Moser, T.
10.1101/2019.12.17.879767 — neuroscience — Posted on 2020-05-28
706 High-resolution population-specific recombination rates and their effect on phasing and genotype imputation
Hassan, S.; Surakka, I.; Taskinen, M.-R.; Salomaa, V.; Palotie, A.; Wessman, M.; Tukiainen, T.; Pirinen, M.; Palta, P.; Ripatti, S.
10.1101/2020.05.20.106831 — genomics — Posted on 2020-05-28
708 CryoSIM: super resolution 3D structured illumination cryogenic fluorescence microscopy for correlated ultra-structural imaging
Phillips, M. A.; Harkiolaki, M.; Pinto, D. M. S.; Parton, R. M.; Palanca, A.; Garcia-Moreno, M.; Kounatidis, I.; Sedat, J.; Stuart, D. I.; Castello, A.; Booth, M. J.; Davis, I.; Dobbie, I. M.
10.1101/2020.03.09.980334 — cell biology — Posted on 2020-05-28
709 Direct digital sensing of proteins in solution through single-molecule optofluidics
Krainer, G.; Saar, K. L.; Arter, W. E.; Jacquat, R. P. B.; Peter, Q.; Challa, P.; Taylor, C. G.; Klenerman, D.; Knowles, T. P. J.
10.1101/2020.05.24.113498 — biophysics — Posted on 2020-05-28
710 iMAC: An interactive atlas to explore phenotypic differences between in vivo, ex vivo and in vitro-derived myeloid cells in the Stemformatics platform
Rajab, N.; Angel, P.; Deng, Y.; Gu, J.; Jameson, V.; Kurowska-Stolarska, M.; Milling, S.; Pacheco, C.; Pacheco Rivera, C.; Rutar, M.; Laslett, A. L.; Le Cao, K.-A.; Choi, J.; Wells, C. A.
10.1101/719237 — systems biology — Posted on 2020-05-28
711 Medical relevance of common protein-altering variants in GPCR genes across 337,205 individuals in the UK Biobank
DeBoever, C.; Venkatakrishnan, A. J.; Paggi, J. M.; Heydenreich, F. M.; Laurin, S.-A.; Masureel, M.; Tanigawa, Y.; Venkataraman, G.; Bouvier, M.; Dror, R. O.; Rivas, M. A.
10.1101/2019.12.13.876250 — genetics — Posted on 2020-05-28
713 Mitochondrial fatty acid synthesis coordinates mitochondrial oxidative metabolism
Nowinski, S. M.; Solmonson, A.; Rusin, S. F.; Maschek, J. A.; Bensard, C. L.; Fogarty, S.; Jeong, M.-Y.; Lettlova, S.; Berg, J. A.; Morgan, J. T.; Ouyang, Y.; Naylor, B. C.; Paulo, J. A.; Funai, K.; Cox, J.; Gygi, S. P.; Winge, D. R.; DeBerardinis, R.; Rutter, J.
10.1101/2020.05.09.086199 — biochemistry — Posted on 2020-05-28
718 Polycystin-2 ciliary extracellular vesicle release and targeting
Wang, J.; Nikonorova, I. A.; Gu, A.; Sternberg, P. W.; Barr, M. M.
10.1101/2020.04.21.050690 — cell biology — Posted on 2020-05-28
722 Transcriptional and epigenetic characterization of early striosomes identifies Foxf2 and Olig2 as factors required for development of striatal compartmentation and neuronal phenotypic differentiation
Cirnaru, M.-D.; Song, S.; Tshilenge, K.-T.; Corwin, C.; Mleczko, J.; Galicia Aguirre, C.; Benlhabib, H.; Bendl, J.; Fullard, J.; Apontes, P.; Creus Muncunill, J.; Reyah, A.; Moussavi, A. N.; Carlsson, P.; Mooney, S. D.; Roussos, P.; Ellerby, L.; Ehrlich, M. E.
10.1101/2020.05.19.105171 — neuroscience — Posted on 2020-05-28
724 A Prokaryotic Membrane Sculpting BAR Domain Protein
Phillips, D. A.; Zacharoff, L. A.; Hampton, C. M.; Chong, G. W.; Malanoski, A. P.; Metskas, L. A.; Xu, S.; Bird, L. J.; Eddie, B. J.; Jensen, G. J.; Drummy, L. F.; El-Naggar, M. Y.; Glaven, S. M.
10.1101/2020.01.30.926147 — microbiology — Posted on 2020-05-28
725 Developmentally Delayed Epigenetic Reprogramming Underlying the Pathogenesis of Preeclampsia
He, W.; Wei, Y.; Gong, X.; Chang, L.; Jin, W.; Liu, K.; Wang, X.; Xiao, Y.; Zhang, W.; Chen, Q.; Wu, K.; Liang, L.; Liu, J.; Chen, Y.; Guo, H.; Li, X.; Chen, W.; Yang, J.; Qi, Y.; Dong, W.; Fu, M.; Liu, J.; Zhang, Y.; Yin, A.
10.1101/2020.05.08.085290 — genomics — Posted on 2020-05-28
726 Selective Labeling and Identification of the Tumor Cell Proteome of Pancreatic Cancer In Vivo
Azizian, N. G.; Nie, L.; Sullivan, D. K.; Pardo, S.; Molleur, D.; Chen, J.; Weintraub, S. T.; Li, Y.
10.1101/2020.05.25.113670 — cancer biology — Posted on 2020-05-28
727 Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs
Li, Z.; Li, X.; Huang, Y.-Y.; Wu, Y.; Zhou, L.; Liu, R.; Wu, D.; Zhang, L.; Liu, H.; Xu, X.; Zhang, Y.; Cui, J.; Zhan, C.-G.; Wang, X.; Luo, H.-B.
10.1101/2020.03.23.004580 — biophysics — Posted on 2020-05-28
730 Evolutionary Response to Resource Deprivation: Parallelism and Nonmonotonicity
Behringer, M. G.; Ho, W.-C.; Miller, S. F.; Meraz, J. C.; Boyer, G. F.; Lynch, M.
10.1101/865584 — evolutionary biology — Posted on 2020-05-28
731 Spatiotemporal Evaluation of The Human Footprint in Colombia: Four Decades of Anthropic Impact in Highly Biodiverse Ecosystems
Correa Ayram, C. A.; Rothlisberger, A. E.; Diaz Timote, J. J.; Rodriguez Buritica, S.; Ramirez, W.; Corzo, G.
10.1101/2020.05.15.098855 — ecology — Posted on 2020-05-28
734 Role of Diversity-Generating Retroelements for Regulatory Pathway Tuning in Cyanobacteria
Vallota-Eastman, A.; Arrington, E. C.; Meeken, S.; Roux, S.; Rosen, S.; Dasari, K.; Miller, J. F.; Valentine, D. L.; Paul, B. G.
10.1101/2020.05.26.117283 — microbiology — Posted on 2020-05-28
738 Management performance mapping and the value of information for regional prioritization of management interventions
Buddenhagen, C.; Andrade-Piedra, J.; Forbes, G. A.; Kromann, P.; Navarrete, I.; Thomas-Sharma, S.; Xing, Y.; Choudhury, R. A.; Andersen, K. F.; Schulte-Geldermann, E.; Garrett, K. A.
10.1101/380352 — ecology — Posted on 2020-05-28
739 Single cell resolution regulatory landscape of the mouse kidney highlights cellular differentiation programs and renal disease targets
Miao, Z.; Balzer, M. S.; Ma, Z.; Liu, H.; Wu, J.; Shrestha, R.; Aranyi, T.; Kwan, A.; Kondo, A.; Pontoglio, M.; Kim, J.; Li, M.; Kaestner, K. H.; Susztak, K.
10.1101/2020.05.24.113910 — developmental biology — Posted on 2020-05-28
741 Brain functional connectivity modulates social bonding in monogamous voles
Lopez-Gutierrez, M. F.; Gracia-Tabuenca, Z.; Ortiz, J. J.; Camacho, F. J.; Young, L. J.; Paredes, R. G.; Diaz, N. F.; Portillo, W.; Alcauter, S.
10.1101/752345 — animal behavior and cognition — Posted on 2020-05-28
742 Enhancing Intracellular Accumulation and Target Engagement of PROTACs with Reversible Covalent Chemistry
Guo, W.-H.; Qi, X.; Yu, X.; Liu, Y.; Chung, C.-I.; Bai, F.; Lin, X.; Lu, D.; Wang, L.; Chen, J.; Su, L.; Nomie, K. J.; Li, F.; Wang, M. C.; Shu, X.; Onuchic, J. N.; Woyach, J. A.; Wang, M. L.; Wang, J.
10.1101/2019.12.30.873588 — pharmacology and toxicology — Posted on 2020-05-28
744 The finger 2 tip loop of Activin A is required for the formation of its non-signaling complex with ACVR1 and type II Bone Morphogenetic Protein receptors
Aykul, S.; Corpina, R. A.; Goebel, E. J.; Cunanan, C. J.; Dimitriou, A.; Kim, H.; Zhang, Q.; Rafique, A.; Leidich, R.; Wang, X.; McClain, J.; Jimenez, J.; Nannuru, K. C.; Rothman, N. J.; Lees-Shepard, J. B.; Thompson, T. B.; Martinez-Hackert, E.; Murphy, A. J.; Economides, A. N.; Idone, V.
10.1101/733147 — cell biology — Posted on 2020-05-28
747 Functional reconstitution of a bacterial CO2 concentrating mechanism in E. coli
Flamholz, A. I.; Dugan, E.; Blikstad, C.; Gleizer, S.; Ben-Nissan, R.; Amram, S.; Antonovsky, N.; Ravishankar, S.; Noor, E.; Bar-Even, A.; Milo, R.; Savage, D.
10.1101/2020.05.27.119784 — synthetic biology — Posted on 2020-05-27
748 Telomere length and oxidative stress variations in a murine model of Alzheimer's disease progression
Martinez-Gonzalez, K. L.; Islas-Hernandez, A.; Martinez-Ezquerro, J. D.; Bermudez-Rattoni, F.; Garcia-delaTorre, P.
10.1101/684365 — neuroscience — Posted on 2020-05-28
749 Haptic metameric textures
Kuroki, S.; Sawayama, M.; Nishida, S.
10.1101/653550 — neuroscience — Posted on 2020-05-28
751 Metabolic cooperation among commensal bacteria supports Drosophila juvenile growth under nutritional stress
Consuegra, J.; Grenier, T.; Akherraz, H.; Rahioui, I.; Gervais, H.; da Silva, P.; Leulier, F.
10.1101/2020.05.27.119370 — microbiology — Posted on 2020-05-27
754 Vpr R36W and R77Q Mutations Alter HIV-1 Replication and Cytotoxicity in T Lymphocytes
Solis-Leal, A.; Karlinsey, D. C.; Lopez, J. B.; Planelles, V.; Poole, B. D.; Berges, B. K.
10.1101/2020.05.26.118174 — microbiology — Posted on 2020-05-27
755 Influenza C and D viral load in cattle correlates with bovine respiratory disease (BRD): Emerging role of orthomyxoviruses in the pathogenesis of BRD
Nissly, R. H.; Zaman, N.; Ibrahim, P. A. S.; McDaniel, K.; Lim, L.; Kiser, J. N.; Bird, I. M.; Chothe, S. K.; Bhushan, G. L.; Vandegrift, K.; Neibergs, H. L.; Kuchipudi, S. V.
10.1101/2020.05.26.118166 — microbiology — Posted on 2020-05-27
758 The crystal structure of SnTox3 from the necrotrophic fungus Parastagonospora nodorum reveals a unique effector fold and insights into Kex2 protease processing of fungal effectors
Outram, M. A.; Sung, Y.-C.; Yu, D.; Dagvadorj, B.; Rima, S.; Jones, D.; Ericsson, D. J.; Sperschneider, J.; Solomon, P.; Kobe, B.; Williams, S. J.
10.1101/2020.05.27.120113 — plant biology — Posted on 2020-05-27
759 Tuberculosis causes highly conserved metabolic changes in human patients, mycobacteria-infected mice and zebrafish larvae
Ding, Y.; Raterink, R. J.; Juez, R. M.; Veneman, W. J.; Egbers, K.; Eeden, S. v. d.; Hak, M. C.; Joosten, S. A.; Ottenhoff, T. H. M.; Harms, A. C.; Alia, A.; Hankemeier, T.; Spaink, H. P.
10.1101/2020.05.25.114470 — molecular biology — Posted on 2020-05-27
760 Azole use in agriculture reduces Aspergillus fumigatus abundance but does not alter its population structure
Barber, A. E.; Riedel, J.; Sae-Ong, T.; Kang, K.; Brabetz, W.; Panagiotou, G.; Deising, H. B.; Kurzai, O.
10.1101/2020.05.26.116616 — microbiology — Posted on 2020-05-27
761 Comparative analysis of macrophage post-translational modifications during intracellular bacterial pathogen infection
Johnson, J. R.; Parry, T.; Repasy, T.; Geiger, K. M.; Verschueren, E.; Budzik, J. M.; Jimenez-Morales, D.; Newton, B. W.; Powell, E.; Coscoy, L.; Portnoy, D. A.; Krogan, N. J.; Cox, J. S.
10.1101/2020.05.27.116772 — microbiology — Posted on 2020-05-27
762 A refined set of rRNA-targeted oligonucleotide probes for in situ detection and quantification of ammonia-oxidizing bacteria
Lukumbuzya, M.; Kristensen, J. M.; Kitzinger, K.; Pommerening-Roeser, A.; Nielsen, P. H.; Wagner, M.; Daims, H.; Pjevac, P.
10.1101/2020.05.27.119446 — microbiology — Posted on 2020-05-27
763 High-resolution yeast quiescence profiling in human-like media reveals interacting influences of auxotrophy and nutrient availability
Santos, S. L.; Laflin, S.; Broadway, A.; Burnett, C.; Hartheimer, J.; Rodgers, J. W.; Smith, D. L.; Hartman, J. L.
10.1101/2020.05.25.114801 — genetics — Posted on 2020-05-27
765 Searching for biological feedstock material: 3D printing of wood particles from house borer and drywood termite frass
Guenster, J.; Plarre, R.; Zocca, A.; Spitzer, A.; Benemann, S.; Gorbushina, A. A.; Li, Y.; Wilbig, J.
10.1101/2020.05.27.118562 — bioengineering — Posted on 2020-05-27
766 Functional microRNA targetome undergoes degeneration-induced shift in the retina
Chu-Tan, J. A.; Feng, Z.-P.; Wooff, Y.; Cioanca, A. V.; Schumann, U.; Aggio-Bruce, R.; Patel, H. R.; Rutar, M.; Hannan, K.; Panov, K.; Provis, J.; Natoli, R.
10.1101/2020.05.27.118307 — molecular biology — Posted on 2020-05-27
767 Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time
Barnes, K. G.; Lachenauer, A. E.; Nitido, A.; Siddiqui, S.; Gross, R.; Beitzel, B.; Siddle, K. J.; Freije, C. A.; Dighero-Kemp, B.; Mehta, S.; Carter, A.; Uwanibe, J.; Ajogbasile, F.; Olumade, T. J.; Odia, I.; Sandi, J. D.; Momoh, M.; Metsky, H. C.; Boehm, C. K.; Lin, A. E.; Kemball, M.; Park, D. J.; Grant, D. S.; Happi, C. T.; Branco, L.; Boisen, M.; Sullivan, B. M.; Amare, M.; Tiamiyu, A.; Parker, Z.; Iroezindu, M.; Modjarrad, K.; Myhrvold, C.; Garry, R. F.; Palacios, G.; Hensley, L. E.; Schaffner, S. F.; Colubri, A.; Sabeti, P. C.
10.1101/2020.05.26.116442 — molecular biology — Posted on 2020-05-27
768 Systematic Discovery of Pseudomonad Genetic Factors Involved in Sensitivity to Tailocins
Carim, S.; Azadeh, A. L.; Kazakov, A. E.; Price, M. N.; Walian, P. J.; Chakraborty, R.; Deutschbauer, A. M.; Mutalik, V. K.; Arkin, A. P.
10.1101/2020.05.27.113977 — microbiology — Posted on 2020-05-27
769 LESR2 is a lymphatic endothelial-specific lncRNA that governs cell proliferation and migration through KLF4 and SEMA3C
Ducoli, L.; Agrawal, S.; Sibler, E.; Kouno, T.; Tacconi, C.; Hon, C.-C.; Berger, S. D.; Muellhaupt, D.; He, Y.; D'Addio, M.; Dieterich, L.; Carninci, P.; de Hoon, M. J. L.; Shin, J. W.; Detmar, M.
10.1101/2020.05.25.114546 — genomics — Posted on 2020-05-27
772 Content-Based Similarity Search in Large-Scale DNA Data Storage Systems
Bee, C.; Chen, Y.-J.; Ward, D.; Liu, X.; Seelig, G.; Strauss, K.; Ceze, L. H.
10.1101/2020.05.25.115477 — bioengineering — Posted on 2020-05-27
774 Dual thermal ecotypes detected within a nearly genetically-identical population of the unicellular marine cyanobacterium Synechococcus
Kling, J.; Lee, M. D.; Webb, E. A.; Coelho, J. T.; Wilburn, P.; Anderson, S. I.; Zhou, Q.; Wang, C.; Phan, M. D.; Kremer, C. T.; Litchman, E.; Rynearson, T. A.; Hutchins, D. A.
10.1101/2020.05.27.119842 — microbiology — Posted on 2020-05-27
776 Contribution of segment 3 to the acquisition of virulence in contemporary H9N2 avian influenza viruses
Clements, A. L.; Sealy, J. E.; Peacock, T. P.; Sadeyen, J.-R.; Hussain, S.; Lycett, S. J.; Shelton, H.; Digard, P.; Iqbal, M.
10.1101/2020.05.27.119917 — microbiology — Posted on 2020-05-27
778 Time-course Profiling of Bovine Herpesvirus Type 1 and Host Cell Transcriptomes using Multiplatform Sequencing
Moldovan, N.; Maroti, Z.; Torma, G.; Gulyas, G.; Hornyak, A.; Zadori, Z.; Jefferson, V. A.; Csabai, Z.; Boldogkoi, M.; Kalmar, T.; Tombacz, D.; Meyer, F.; Boldogkoi, Z.
10.1101/2020.05.25.114843 — genomics — Posted on 2020-05-27
781 Reprogramming of serine metabolism is an actionable vulnerability in FLT3-ITD driven acute myeloid leukaemia
Bjelosevic, S.; Gruber, E.; Newbold, A.; Kats, L. M.; Shembrey, C.; Abrehart, T. C.; Todorovski, I.; Pomilio, G.; Wei, A. H.; Gregory, G. P.; Vervoort, S. J.; Brown, K. K.; Johnstone, R. W.
10.1101/2020.05.26.116392 — cancer biology — Posted on 2020-05-27
787 Spatial separation of Streptomyces aerial mycelium during fermentation enhances secondary metabolite production
Muralikrishnan, B.; R J, R.; Ramachandran, R.; J S, V.; M, N.; K B, A.; Paul, L.; Dastager, S. G.; Dan, V. M.; Ramakrishnan, A. K.
10.1101/2020.05.27.118091 — microbiology — Posted on 2020-05-27
788 Diffusion assessment through image processing: beyond the point-source paradigm
Postnikov, E. B.; Namykin, A. A.; Semyachkina-Glushkovskaya, O. V.; Postnov, D. E.
10.1101/2020.05.27.118588 — biophysics — Posted on 2020-05-27
789 SARS-CoV-2 envelope protein topology in eukaryotic membranes
Duart, G.; Garcia-Murria, M. J.; Grau, B.; Acosta-Caceres, J. M.; Martinez-Gil, L.; Mingarro, I.
10.1101/2020.05.27.118752 — biochemistry — Posted on 2020-05-27
791 Molecular detection of pathogens in ticks and fleas collected from companion dogs and cats in East and Southeast Asia
Nguyen, V.-L.; Colella, V.; Greco, G.; Fang, F.; Nurcahyo, W.; Hadi, U. K.; Venturina, V.; Tong, K. B. Y.; Tsai, Y.-L.; Taweethavonsawat, P.; Tiwananthagorn, S.; Tangtrongsup, S.; Le, T. Q.; Bui, K. L.; Do, T.; Watanabe, M.; Rani, P. A. M. A.; Dantas-Torres, F.; Halos, L.; Beugnet, F.; Otranto, D.
10.1101/2020.05.27.118554 — molecular biology — Posted on 2020-05-27
793 Impact of Comorbidities on the Expression of SARS-CoV-2 Viral Entry-Related Genes
Breidenbach, J. D.; Dube, P.; Ghosh, S.; Modyanov, N. N.; Malhotra, D.; Dworkin, L. D.; Haller, S. T.; Kennedy, D. J.
10.1101/2020.05.26.117440 — microbiology — Posted on 2020-05-27
794 Different pattern of pre-existing SARS-COV-2 specific T cell immunity in SARS-recovered and uninfected individuals
Le Bert, N.; Tan, A. T.; Kunasegaran, K.; Tham, C. Y. L.; Hafezi, M.; Chia, A.; Chng, M.; Lin, M.; Tan, N.; Linster, M.; Chia, W. N.; Chen, M. I.-C.; Wang, L.-F.; Ooi, E. E.; Kalimuddin, S.; Tambyah, P. A.; Low, J. G.-H.; Tan, Y.-J.; Bertoletti, A.
10.1101/2020.05.26.115832 — immunology — Posted on 2020-05-27
798 Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19
Mirabelli, C.; Wotring, J. W.; Zhang, C. J.; McCarty, S. M.; Fursmidt, R.; Kadambi, N. S.; Amin, A. T.; O'Meara, T. R.; Pretto-Kernahan, C. D.; Spence, J. R.; Frum, T.; Alysandratos, K. D.; Huang, J.; Kotton, D. N.; Wobus, C. E.; Weatherwax, K. J.; Mashour, G. A.; Handelman, S. K.; O'Meara, M. J.; Sexton, J. Z.
10.1101/2020.05.27.117184 — cell biology — Posted on 2020-05-27
799 Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease
Douangamath, A.; Fearon, D.; Gehrtz, P.; Krojer, T.; Lukacik, P.; Owen, C. D.; Resnick, E.; Strain-Damerell, C.; aimon, A.; Abranyi-Balogh, P.; Brandao-Neto, J.; Carberry, A.; Davison, G.; Dias, A.; Downes, T. D.; Dunnett, L.; Fairhead, M.; Firth, J. D.; Jones, S. P.; Keely, A.; Keserü, G. M.; Klein, H. F.; Martin, M. P.; Noble, M. E. M.; O'Brien, P.; Powell, A.; Reddi, R.; Skyner, R.; Snee, M.; Waring, M. J.; Wild, C.; London, N.; von Delft, F.; Walsh, M. A.
10.1101/2020.05.27.118117 — biophysics — Posted on 2020-05-27
801 Development and validation of IMMUNO-COV: a high-throughput clinical assay for detecting antibodies that neutralize SARS-CoV-2
Vandergaast, R.; Carey, T.; Reiter, S.; Lech, P.; Gnanadurai, C.; Tesfay, M.; Buehler, J.; Suksanpaisan, L.; Naik, S.; Brunton, B.; Recker, J.; Haselton, M.; Ziegler, C.; Roesler, A.; Mills, J. R.; Theel, E.; Weaver, S. C.; Rafael, G.; Roforth, M. M.; Jerde, C.; Tran, S.; Diaz, R. M.; Bexon, A.; Baum, A.; Kyratsous, C. A.; Peng, K.-W.; Russell, S. J.
10.1101/2020.05.26.117549 — immunology — Posted on 2020-05-27
802 Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling
Goldman-Israelow, B.; Song, E.; Mao, T.; Lu, P.; Meir, A.; Liu, F.; Madel Alfajaro, M.; Wei, J.; Dong, H.; Homer, R.; Ring, A.; Wilen, C. B.; Iwasaki, A.
10.1101/2020.05.27.118893 — immunology — Posted on 2020-05-27
804 Convergent and distributed effects of the schizophrenia-associated 3q29 deletion on the human neural transcriptome
Sefik, E.; Purcell, R. H.; Merritt-Garza, M.; Karne, S.; Randall, J.; The Emory 3q29 Project, ; Walker, E. F.; Bassell, G. J.; Mulle, J. G.
10.1101/2020.05.25.111351 — genetics — Posted on 2020-05-27
805 Discovery of novel haplotypes for complex traits in landraces
Mayer, M.; Hoelker, A. C.; Gonzalez-Segovia, E.; Presterl, T.; Ouzunova, M.; Melchinger, A. E.; Schoen, C.-C.
10.1101/2020.05.25.114264 — genetics — Posted on 2020-05-27
806 An exploratory rehearsal on AIE dots assisted NIR-II fluorescence non-human primates imaging
Feng, Z.; Bai, S.; Qi, J.; Sun, C.; Zhang, Y.; Yu, X.; Ni, H.; Wu, D.; Fan, X.; Xue, D.; Gong, J.; Wei, P.; He, M.; Lam, J. W. Y.; Li, X.; Tang, B. Z.; Gao, L.; Qian, J.
10.1101/2020.05.26.113316 — bioengineering — Posted on 2020-05-27
808 Male linked genomic regions determine sex in dioecious Amaranthus palmeri
Neves, C. J.; Matzrafi, M.; Thiele, M.; Lorant, A.; Mesgaran, M. B.; Stetter, M. G.
10.1101/2020.05.25.113597 — plant biology — Posted on 2020-05-27
812 Controlling wireframe DNA origami nuclease degradation with minor groove binders
Wamhoff, E.-C.; Huang, H.; Read, B. J.; Ginsburg, E.; Schief, W. R.; Farrell, N.; Irvine, D. J.; Bathe, M.
10.1101/2020.05.24.110783 — bioengineering — Posted on 2020-05-27
813 Chromosome-scale assembly and annotation of the macadamia genome(Macadamia integrifolia HAES 741)
Nock, C. J.; Baten, A.; Mauleon, R.; Langdon, K. S.; Topp, B.; Hardner, C. M.; Furtado, A.; Henry, R. J.; King, G. J.
10.1101/2020.05.25.114009 — genomics — Posted on 2020-05-27
814 3D chromatin organization changes modulate adipogenesis and osteogenesis
Hao, R.-H.; Guo, Y.; Guo, J.; Rong, Y.; Yao, S.; Chen, Y.-X.; Dong, S.-S.; Zhu, D.-L.; Chen, H.; Yang, T.-L.
10.1101/2020.05.25.114272 — genetics — Posted on 2020-05-27
817 Data quantity is more important than its spatial bias for predictive species distribution modelling
Gaul, W. B.; Sadykova, D.; White, H. J.; Leon-Sanchez, L.; Caplat, P.; Emmerson, M. C.; Yearsley, J. M.
10.1101/2020.05.24.113415 — ecology — Posted on 2020-05-27
820 A unique small molecule pair controls the plant circadian clock
Uehara, T. N.; Takao, S.; Matsuo, H.; Saito, A. N.; Ota, E.; Ono, A.; Itami, K.; Kinoshita, T.; Yamaguchi, J.; Nakamichi, N.
10.1101/2020.05.25.113746 — plant biology — Posted on 2020-05-27
822 Phenotypic changes of bacteria through opportunity and global methylation leads to antibiotic resistance
Neerathilingam, M.; Mysore, S.; Bairy, S.; Chandola, C.; Varadharajan, V.; Rajasekharan, R.
10.1101/2020.05.27.114090 — microbiology — Posted on 2020-05-27
829 Transcription factor TGA2 is essential for UV-B stress tolerance controlling oxidative stress in Arabidopsis
Herrera-Vasquez, A.; Fonseca, A.; Ugalde, J. M.; Lamig, L.; Seguel, A.; Moyano, T.; Gutierrez, R. A.; Salinas, P.; Vidal, E.; Holuigue, L.
10.1101/2020.05.24.113589 — plant biology — Posted on 2020-05-27
830 Gsta4 controls apoptosis of differentiating adult oligodendrocytes during homeostasis and remyelination via the mitochondria-associated Fas/Casp8/Bid-axis
Carlstrom, K. E.; Zhu, K.; Ewing, E.; Krabbendam, I.; Harris, R. A.; Mendanha Falcao, A.; Jagodic, M.; Castelo Branco, G.; Piehl, F.
10.1101/2020.05.26.111856 — neuroscience — Posted on 2020-05-27
832 A framework for in situ molecular characterization of coral holobionts using nanopore sequencing
Carradec, Q.; Poulain, J.; Boissin, E.; Hume, B. C.; Voolstra, C. R.; Ziegler, M.; Engelen, S.; Cruaud, C.; Planes, S.; Wincker, P.
10.1101/2020.05.25.071951 — genomics — Posted on 2020-05-27
833 Anopheles mosquitoes revealed new principles of 3D genome organization in insects
Lukyanchikova, V.; Nuriddinov, M.; Belokopytova, P.; Liang, J.; Reijnders, M. J. M. F.; Ruzzante, L.; Waterhouse, R. M.; Tu, Z.; Sharakhov, I. V.; Fishman, V.
10.1101/2020.05.26.114017 — genomics — Posted on 2020-05-27
836 Haplotype tagging reveals parallel formation of hybrid races in two butterfly species
Meier, J. I.; Salazar, P. A.; Kucka, M.; Davies, R. W.; Dreau, A.; Aldas, I.; Box Power, O.; Nadeau, N. J.; Bridle, J. R.; Rolian, C. P.; Barton, N. H.; McMillan, W. O.; Jiggins, C. D.; Chan, Y. F.
10.1101/2020.05.25.113688 — evolutionary biology — Posted on 2020-05-27
838 Modeling IKZF1 lesions in B-ALL reveals distinct chemosensitivity patterns and potential therapeutic vulnerabilities
Rogers, J. H.; Gupta, R.; Reyes, J. M.; Gundry, M.; Medrano, G.; Guzman, A.; Song, T.; Johnson, C.; Barnes, S.; Cristobal, C. D. D.; Brunetti, L.; Goodell, M. A.; Rau, R. E.
10.1101/2020.05.26.109579 — cancer biology — Posted on 2020-05-27
840 Dynamic Loading of Human Engineered Heart Tissue Enhances Contractile Function and Drives Desmosome-linked Disease Phenotype
Bliley, J. M.; Vermeer, M.; Duffy, R. M.; Batalov, I.; Kramer, D.; Tashman, J. W.; Shiwarski, D. J.; Lee, A.; Teplenin, A. S.; Volkers, L.; Coffin, B.; Hoes, M. F.; Kalmykov, A.; Palchesko, R. N.; Sun, Y.; Jongbloed, J. D. H.; Bomer, N.; de Boer, R. A.; Suurmeijer, A. J. H.; Pijnappels, D. A.; Bolling, M. C.; Meer, P. v. d.; Feinberg, A. W.
10.1101/2020.05.25.111690 — bioengineering — Posted on 2020-05-27
843 A cortico-collicular circuit for accurate orientation to shelter during escape
Vale, R.; Campagner, D.; Iordanidou, P.; Arocas, O. P.; Tan, Y. L.; Stempel, A. V.; Sepideh Keshavarzi, S.; Petersen, R.; Margrie, T.; Branco, T.
10.1101/2020.05.26.117598 — neuroscience — Posted on 2020-05-27
845 An improved CRISPR/dCas9 interference tool for neuronal gene suppression
Duke, C. G.; Bach, S. V.; Revanna, J. S.; Sultan, F. A.; Southern, N. T.; Davis, M. N.; Gallus, N. V. N.; Bauman, A. J.; Phillips, R. A.; Day, J. J.
10.1101/2020.05.26.116822 — neuroscience — Posted on 2020-05-27
846 Neuronal circuitry underlying female aggression in Drosophila
Rubin, G. M.; Schretter, C. E.; Aso, Y.; Dreher, M.; Robie, A. A.; Dolan, M.-J.; Chen, N.; Ito, M.; Yang, T.; Parekh, R.
10.1101/2020.05.27.118810 — neuroscience — Posted on 2020-05-27
848 Chromatin arranges in chains of mesoscale domains with nanoscale functional topography independent of cohesin
Miron, E.; Oldenkamp, R.; Brown, J. M.; Pinto, D. M.; Xu, C. S.; Faria, A. R.; Shaban, H. A.; Rhodes, J. D.; Innocent, C.; de Ornellas, S.; Hess, H.; Buckle, V.; Schermelleh, L.
10.1101/566638 — genomics — Posted on 2020-05-27
849 Fluorescent secreted bacterial effectors reveal an intravacuolar replication compartment for Listeria monocytogenes
Peron Cane, C.; Leblanc, J.; Wingertsmann, L.; Fernandez, J.-C.; Gautier, A.; Desprat, N.; Lebreton, A.
10.1101/2019.12.23.886689 — microbiology — Posted on 2020-05-27
850 Deep Learning for Alzheimer's Disease: Mapping Large-scale Histological Tau Protein for Neuroimaging Biomarker Validation
Alegro, M.; Chen, Y.; Ovando, D.; Heinsen, H.; Eser, R.; Ushizima, D.; Tosun, D.; Grinberg, L.
10.1101/698902 — neuroscience — Posted on 2020-05-27
853 Hearing restoration by a low-weight power-efficient multichannel optogenetic cochlear implant system
Jablonski, L.; Harczos, T.; Wolf, B.; Hoch, G.; Dieter, A.; Hessler, R.; Ayub, S.; Ruther, P.; Moser, T.
10.1101/2020.05.25.114868 — neuroscience — Posted on 2020-05-27
854 Integrated hiPSC-based liver and heart microphysiological systems predict unsafe drug-drug interaction
Lee-Montiel, F. T.; Laemmle, A.; Dumont, L.; Lee, C. S.; Huebsch, N.; Charwat, V.; Okochi, H.; Hancock, M. J.; Siemons, B.; Bogess, S.; Goswami, I.; Miller, E.; Willenbring, H.; Healy, K.
10.1101/2020.05.24.112771 — bioengineering — Posted on 2020-05-27
856 Tolerance induction in memory CD4 T cells is partial and reversible
Gray, J. I.; Al Khabouri, S.; Morton, F.; Clambey, E.; Gapin, L.; Matsuda, J. L.; Kappler, J. W.; Marrack, P.; Garside, P.; Otto, T. D.; MacLeod, M. K.
10.1101/2020.05.25.114785 — immunology — Posted on 2020-05-27
858 Cell states beyond transcriptomics: integrating structural organization and gene expression in hiPSC-derived cardiomyocytes
Gerbin, K. A.; Grancharova, T.; Donovan-Maiye, R.; Hendershott, M. C.; Brown, J.; Dinh, S. Q.; Gehring, J. L.; Hirano, M.; Johnson, G. R.; Nath, A.; Nelson, A.; Roco, C. M.; Rosenberg, A. B.; Sluzewski, M. F.; Viana, M. P.; Yan, C.; Zaunbrecher, R. J.; Cordes Metzler, K. R.; Menon, V.; Palecek, S. P.; Seelig, G.; Gaudreault, N.; Knijnenburg, T.; Rafelski, S. M.; Theriot, J. A.; Gunawardane, R. N.
10.1101/2020.05.26.081083 — cell biology — Posted on 2020-05-27
859 Autoregulatory circuit regulating basolateral cargo export from the TGN: role of the orphan receptor GPRC5A in PKD signaling and cell polarity.
Di Martino, R.; Capalbo, A.; Sticco, L.; Varavallo, A.; Kunnathully, V.; De Luca, V.; Iyengar, N. R.; Lo Monte, M.; Henklein, P.; Cancino, J.; Luini, A.
10.1101/2020.05.26.114710 — cell biology — Posted on 2020-05-27
860 RT-qPCR analyses on the osteogenic differentiation from human iPS cells: An investigation of reference genes
Okamura, K.; Inagaki, Y.; Matsui, T. K.; Matsubayashi, M.; Komeda, T.; Ogawa, M.; Mori, E.; Tanaka, Y.
10.1101/2020.05.27.118000 — cell biology — Posted on 2020-05-27
863 Temporal control of tumor growth in nocturnal mammals: impact of the circadian system
Wagner, P. M.; Prucca, C.; Velazquez, F.; Sosa Alderete, L.; Caputto, B. L.; GUIDO, M. E.
10.1101/2020.05.25.114652 — cancer biology — Posted on 2020-05-27
864 Selective Labeling and Identification of the Tumor Cell Proteome of Pancreatic Cancer In Vivo
Azizian, N. G.; Nie, L.; Sullivan, D. K.; Pardo, S.; Molleur, D.; Chen, J.; Weintraub, S. T.; Li, Y.
10.1101/2020.05.25.113670 — cancer biology — Posted on 2020-05-27
867 Direct digital sensing of proteins through single-molecule optofluidics
Krainer, G.; Saar, K. L.; Arter, W. E.; Jacquat, R. P. B.; Peter, Q.; Challa, P.; Taylor, C. G.; Klenerman, D.; Knowles, T. P. J.
10.1101/2020.05.24.113498 — biophysics — Posted on 2020-05-27
870 Enhancing CRISPR deletion via pharmacological delay of DNA-PK
Bosch, N.; Medova, M.; Esposito, R.; Pulido-Quetglas, C.; Zimmer, Y.; Johnson, R.
10.1101/2020.02.12.945907 — molecular biology — Posted on 2020-05-27
871 Timing of fruiting rather than topography determines the direction of vertical seed dispersal by mammals and birds
Tsunamoto, Y.; Koike, S.; Tayasu, I.; Masaki, T.; Kato, S.; Kikuchi, S.; Nagamitsu, T.; Haraguchi, T.; Naganuma, T.; Naoe, S.
10.1101/2020.05.24.112987 — ecology — Posted on 2020-05-27
874 Benchmarking atlas-level data integration in single-cell genomics
Luecken, M. D.; Büttner, M.; Chaichoompu, K.; Danese, A.; Interlandi, M.; Müller, M. F.; Strobl, D. C.; Zappia, L.; Dugas, M.; Colome-Tatche, M.; Theis, F. J.
10.1101/2020.05.22.111161 — bioinformatics — Posted on 2020-05-27
877 Low-disturbance Farming Regenerates Healthy Deep Soil towards Sustainable Agriculture
Deng, F.; Wang, H.; Xie, H.; Bao, X.; He, H.; Zhang, X.; Liang, C.
10.1101/828673 — ecology — Posted on 2020-05-27
878 Low-disturbance Farming Regenerates Healthy Deep Soil towards Sustainable Agriculture
Deng, F.; Wang, H.; Xie, H.; Bao, X.; He, H.; Zhang, X.; Liang, C.
10.1101/828673 — ecology — Posted on 2020-05-27
879 Low-disturbance Farming Regenerates Healthy Deep Soil towards Sustainable Agriculture
Deng, F.; Wang, H.; Xie, H.; Bao, X.; He, H.; Zhang, X.; Liang, C.
10.1101/828673 — ecology — Posted on 2020-05-27
880 Reduced RNA turnover as a driver of cellular senescence
Mullani, N.; Porozhan, Y.; Costallat, M.; Batsche, E.; Goodhardt, M.; Cenci, G.; Mann, C.; Muchardt, C.
10.1101/800128 — molecular biology — Posted on 2020-05-27
881 Genomic Surveillance of Yellow Fever Virus Epizootic in Sao Paulo, Brazil, 2016 - 2018
Hill, S. C.; de Souza, R. P.; Theze, J.; Claro, I.; Aguiar, R. S.; Abade, L.; Santos, F. C. P.; Cunha, M. S.; Nogueira, J. S.; Salles, F. F. C.; Rocco, I. M.; Maeda, A. Y.; Vasami, F. G. S.; Plessis, L. d.; Silveira, P. P.; de Jesus, J. G.; Quick, J.; Fernandes, N. C. C. A.; Guerra, J. M.; Ressio, R. A.; Giovanetti, M.; Alcantara, L. C. J.; Cirqueira, C. S.; Delagado, J. D.; Macedo, F. L. L.; Timenetsky, M. C. S. T.; de Paula, R.; Spinola, R.; de Deus, J. T.; Mucci, L. F.; Tubaki, R. M.; de Menezes, R. M. T.; Ramos, P. L.; de Abreu, A. L.; da Cruz, L. N.; Loman, N.; Dellicour, S.; Pybus, O. G.
10.1101/645341 — epidemiology — Posted on 2020-05-27
883 AmpliconDesign - An interactive web server for the design of high-throughput targeted DNA methylation assays
Schoenung, M.; Hess, J.; Bawidamann, P.; Staeble, S.; Hey, J.; Langstein, J.; Assenov, Y.; Weichenhan, D.; Lutsik, P.; Lipka, D. B.
10.1101/2020.05.23.043448 — bioinformatics — Posted on 2020-05-27
889 Core Fermentation (CoFe) granules focus coordinated glycolytic mRNAlocalization and translation to fuel glucose fermentation
Morales-Polanco, F.; Bates, C.; Lui, J.; Casson, J.; Solari, C. A.; Pizzinga, M.; Forte, G.; Burt, H. E.; Dixon, H. L.; Griffin, C.; Hubbard, S. J.; Portela, P.; Ashe, M. P.
10.1101/741231 — cell biology — Posted on 2020-05-27
890 Role of RNA Guanine Quadruplexes in Favoring the Dimerization of SARS Unique Domain in Coronaviruses
Hognon, C.; Miclot, T.; Garcia Iriepa, C.; France-Monerris, A.; Grandemange, S.; Terenzi, A.; Marazzi, M.; Barone, G.; Monari, A.
10.1101/2020.04.07.029447 — biophysics — Posted on 2020-05-27
891 Relationship between simultaneously recorded spiking activity and fluorescence signal in GCaMP6 transgenic mice
Huang, L.; Knoblich, U.; Ledochowitsch, P.; Lecoq, J.; Reid, R. C.; de Vries, S. E. J.; Buice, M. A.; Murphy, G. J.; Waters, J.; Koch, C.; Zeng, H.; Li, L.
10.1101/788802 — neuroscience — Posted on 2020-05-27
892 PelX is a UDP-N-acetylglucosamine C4-epimerase involved in Pel polysaccharide-dependent biofilm formation
Marmont, L. S.; Whitfield, G. B.; Pfoh, R.; Williams, R. J.; Randall, T. E.; Ostaszewski, A.; Razvi, E.; Groves, R. A.; Robinson, H.; Nitz, M.; Parsek, M. R.; Lewis, I. A.; Whitney, J. C.; Harrison, J. J.; Howell, P. L.
10.1101/2020.05.26.111013 — microbiology — Posted on 2020-05-27
893 DNA Binding Induces a cis to trans Switch in Cre Recombinase to Enable Intasome Assembly
Unnikrishnan, A.; Amero, C. D.; Yadav, D. K.; Stachowski, K.; Potter, D.; Foster, M.
10.1101/2020.05.24.113654 — biophysics — Posted on 2020-05-27
895 Endothelial CXCL12 regulates neovascularization during tissue repair and tumor progression
Maan, Z. N.; Hu, M. S.; Rennert, R.; Barrera, J. A.; Duscher, D.; Januszyk, M.; Whittam, A.; Padmanabhan, J.; Vial, I.; Ho, N.; Fischer, L. H.; Riegler, J.; Wu, J. C.; Longaker, M. T.; Gurtner, G.
10.1101/2020.05.24.113845 — molecular biology — Posted on 2020-05-27
896 A global data-driven census of Salmonella small proteins and their potential functions in bacterial virulence
Venturini, E.; Svensson, S. L.; Maass, S.; Gelhausen, R.; Eggenhofer, F.; Li, L.; Cain, A. K.; Parkhill, J.; Becher, D.; Backofen, R.; Barquist, L.; Sharma, C. M.; Westermann, A. J.; Vogel, J.
10.1101/2020.05.26.116038 — microbiology — Posted on 2020-05-27
898 TLR9-activated B cells improve their regulatory function by endogenously produced catecholamines
Honke, N.; Lowin, T.; Opgenoorth, B.; Shaabani, N.; Lautwein, A.; Teijaro, J. R.; Schneider, M.; Pongratz, G.
10.1101/2020.05.24.113167 — immunology — Posted on 2020-05-27
901 Choanoflagellates and the ancestry of neurosecretory vesicles
Gohde, R.; Nauman, B.; Laundon, D.; Imig, C.; McDonald, K. L.; Cooper, B. H.; Varoqueaux, F.; Fasshauer, D.; Burkhardt, P.
10.1101/2020.05.24.111997 — evolutionary biology — Posted on 2020-05-27
904 Capsule Networks as Recurrent Models of Grouping and Segmentation
Doerig, A.; Schmittwilken, L.; Sayim, B.; Manassi, M.; Herzog, M. H.
10.1101/747394 — neuroscience — Posted on 2020-05-27
905 Role of Diversity-Generating Retroelements for Regulatory Pathway Tuning in Cyanobacteria
Vallota-Eastman, A.; Arrington, E. C.; Meeken, S.; Roux, S.; Rosen, S.; Dasari, K.; Miller, J. F.; Valentine, D. L.; Paul, B. G.
10.1101/2020.05.26.117283 — microbiology — Posted on 2020-05-27
908 Meltwater runoff from the Greenland Ice Sheet reveals microbial consortia from contrasting subglacial drainage systems
Lamarche-Gagnon, G.; Anesio, A. M.; Wadham, J. L.; Zarsky, J. D.; Kohler, T. J.; Bagshaw, E. A.; Telling, J.; Hawkings, J. R.; Stibal, M.
10.1101/2020.05.26.116566 — microbiology — Posted on 2020-05-27
911 PYK2 controls intestinal inflammation via activation of IRF5 in macrophages
Ryzhakov, G.; Almuttaqi, H.; Corbin, A. L.; Khoyratty, T.; Berthold, D.; Bullers, S.; Eames, H. L.; Ai, Z.; Bonham, S.; Fischer, R.; Jostins-Dean, L.; Travis, S. P. L.; Kessler, B. M.; Udalova, I. A.
10.1101/2020.05.24.113076 — immunology — Posted on 2020-05-27
912 A population genomic unveiling of a new cryptic mosquito taxon within the malaria-transmitting Anopheles gambiae complex
Tennessen, J. A.; Ingham, V. A.; Toe, K. H.; Guelbeogo, W. M.; Sagnon, N.; Kuzma, R.; Ranson, H.; Neafsey, D. E.
10.1101/2020.05.26.116988 — evolutionary biology — Posted on 2020-05-27
913 Molecular interaction mechanism of 14-3-3ε protein with phosphorylated Myeloid leukemia factor 1 revealed by an enhanced conformational sampling
Higo, J.; Kawabata, T.; Kusaka, A.; Kasahara, K.; Kamiya, N.; Fukuda, I.; Mori, K.; Hata, Y.; Fukunishi, Y.; Nakamura, H.
10.1101/2020.05.24.113209 — biophysics — Posted on 2020-05-27
919 Simeprevir suppresses SARS-CoV-2 replication and synergizes with remdesivir
Lo, H. S.; Hui, K. P. Y.; Lai, H.-M.; Khan, K. S.; Kaur, S.; Li, Z.; Chan, A. K. N.; Cheung, H. H.-Y.; Ng, K. C.; Ho, J. C. W.; Che, Y. W.; Ma, B.; Cheung, P. M.-H.; Shin, D.; Wang, K.; Wu, K.-P.; Dikic, I.; Liang, P.-H.; Zuo, Z.; Chan, F. K. L.; Hui, D. S. C.; Mok, V. C. T.; Wong, K.-B.; Ko, H.; Aik, W. S.; Chan, M. C. W.; Ng, W.-L.
10.1101/2020.05.26.116020 — microbiology — Posted on 2020-05-26
924 SciSight: Combining faceted navigation and research group detection for COVID-19 exploratory scientific search
Hope, T.; Portenoy, J.; Vasan, K.; Borchardt, J.; Horvitz, E.; Weld, D. S.; Hearst, M. A.; West, J.
10.1101/2020.05.23.112284 — bioinformatics — Posted on 2020-05-26
930 Ebola and Marburg virus infection in bats is controlled by a systemic response
Jayaprakash, A. D.; Ronk, A. J.; Prasad, A. N.; Covington, M. F.; Stein, K. R.; Schwarz, T. M.; Hekmaty, S.; Fenton, K. A.; Geisbert, T. W.; Basler, C. F.; Bukreyev, A.; Sachidanandam, R.
10.1101/2020.04.13.039503 — microbiology — Posted on 2020-05-26
933 Sources of variation and establishment of Russian reference intervals for major hormones and tumor markers
Ruzhanskaya, A.; Ichihara, K.; Evgina, S.; Skibo, I.; Vybornova, N.; Vasiliev, A.; Agarkova, G.; Emanuel, V.
10.1101/2020.05.26.116269 — biochemistry — Posted on 2020-05-26
936 Task-driven hierarchical deep neural network models of the proprioceptive pathway
Sandbrink, K. J.; Mamidanna, P.; Michaelis, C.; Mathis, M. W.; Bethge, M.; Mathis, A.
10.1101/2020.05.06.081372 — neuroscience — Posted on 2020-05-26
937 Telomere length and oxidative stress in the progression of Alzheimer's disease
Martinez-Gonzalez, K. L.; Islas-Hernandez, A.; Martinez-Ezquerro, J. D.; Bermudez-Rattoni, F.; Garcia-delaTorre, P.
10.1101/684365 — neuroscience — Posted on 2020-05-26
942 Exploring Chromosomal Structural Heterogeneity AcrossMultiple Cell Lines
Cheng, R. R.; Contessoto, V.; Aiden, E. L.; Wolynes, P. G.; Di Pierro, M.; Onuchic, J. N.
10.1101/2020.03.21.001917 — biophysics — Posted on 2020-05-26
943 Inferring Telomerase Enzymatic Activity from Expression Data
Noureen, N.; Wu, S.; Lyu, Y.; Yang, J.; Yung, W. K. A.; Gelfond, J.; Wang, X.; Koul, D.; Ludlow, A.; Zheng, S.
10.1101/2020.05.21.109249 — bioinformatics — Posted on 2020-05-26
947 Longitudinal ComBat: A Method for Harmonizing Longitudinal Multi-scanner Imaging Data
Beer, J. C.; Tustison, N. J.; Cook, P. A.; Davatzikos, C.; Sheline, Y. I.; Shinohara, R. T.; Linn, K. A.
10.1101/868810 — neuroscience — Posted on 2020-05-26
950 Antibody repertoire and gene expression dynamics of diverse human B cell states during affinity maturation.
King, H. W.; Orban, N.; Riches, J. C.; Clear, A. J.; Warnes, G.; Teichmann, S. A.; James, L. K.
10.1101/2020.04.28.054775 — immunology — Posted on 2020-05-26
955 Temperature-dependence of metabolic rate in tropical and temperate aquatic insects: support for the Climate Variability Hypothesis in mayflies but not stoneflies.
Shah, A. A.; Woods, H. A.; Havird, J. C.; Encalada, E. C.; Flecker, A. S.; Funk, W. C.; Guayasamin, J. M.; Kondratieff, B. K.; Poff, N. L.; Thomas, S. A.; Zamudio, K. R.; Ghalambor, C. K.
10.1101/2019.12.25.888578 — ecology — Posted on 2020-05-26
960 A comprehensive benchmarking of WGS-based structural variant callers
Sarwal, V.; Niehus, S.; Ayyala, R.; Chang, S.; Lu, A.; Darci-Maher, N.; Littman, R.; Wesel, E.; Castellanos, J.; Chikka, R.; Distler, M. G.; Eskin, E.; Flint, J.; Mangul, S.
10.1101/2020.04.16.045120 — bioinformatics — Posted on 2020-05-26
962 Shotgun Metagenomics of 361 elderly women reveals gut microbiome change in bone mass loss
Wang, Q.; Sun, Q.; Li, X.; Wang, Z.; Zheng, H.; Ju, Y.; Guo, R.; Peng, S.; Jia, H.
10.1101/679985 — microbiology — Posted on 2020-05-26
963 Immunomodulatory effects of extract of Ganoderma lucidum basidiocarps cultivated on alternative substrate
Bozic Nedeljkovic, B.; Cilerdzic, J.; Zmijanjac, D.; Markovic, M.; Dzopalic, T.; Vasilijic, S.; Stajic, M.; Vucevic, D.
10.1101/603498 — immunology — Posted on 2020-05-26
964 Modeling Epistasis in Mice and Yeast Using the Proportion of Two or More Distinct Genetic Backgrounds: Evidence for "Polygenic Epistasis"
Rau, C. D.; Gonzales, N. M.; Bloom, J. S.; Park, D.; Ayroles, J. S.; Palmer, A. A.; Lusis, A. J.; Zaitlen, N.
10.1101/555383 — genomics — Posted on 2020-05-26
966 Social groups with diverse personalities mitigate physiological stress in a songbird
Vagasi, C. I.; Fulop, A.; Osvath, G.; Pap, P. L.; Penzes, J.; Benko, Z.; Lendvai, A. Z.; Barta, Z.
10.1101/2020.04.15.043471 — ecology — Posted on 2020-05-26
967 Lysosomal cystine efflux opposes mTORC1 reactivation through the TCA cycle
Jouandin, P.; Marelja, Z.; Parkhitko, A.; Dambowsky, M.; Asara, J. M.; Nemazanyy, I.; Dibble, C. C.; Simons, M.; Perrimon, N.
10.1101/606541 — cell biology — Posted on 2020-05-26
970 An endocrine-hepato-muscular metabolic cycle links skeletal muscle atrophy and hyperglycemia in type 2 diabetes
Okun, J. G.; Rusu, P. M.; Chan, A. Y.; Yap, Y. W.; Sharkie, T.; Schumacher, J.; Hille, S.; Schmidt, K.; Zota, A.; Jungmann, A.; Maggi, L.; Lee, Y.; Blueher, M.; Herzig, S.; Heikenwaelder, M.; Mueller, O.; Rose, A. J.
10.1101/2020.05.25.115709 — physiology — Posted on 2020-05-26
972 Scale-invariance in brain activity predicts practice effects in cognitive performance
Kardan, O.; Layden, E. A.; Choe, K. W.; Lyu, M.; Zhang, X.; Beilock, S. L.; Rosenberg, M. D.; Berman, M. G.
10.1101/2020.05.25.114959 — neuroscience — Posted on 2020-05-26
973 The impact of daily caffeine intake on nighttime sleep: signs of overnight withdrawal?
Weibel, J.; Lin, Y.-S.; Landolt, H.-P.; Kistler, J.; Rehm, S.; Rentsch, K. M.; Slawik, H.; Borgwardt, S.; Cajochen, C.; Reichert, C. F.
10.1101/2020.05.26.114769 — neuroscience — Posted on 2020-05-26
975 A simple RNA preparation method for SARS-CoV-2 detection by RT-qPCR
Wozniak, A.; Cerda, A.; Ibarra-Henriquez, C.; Sebastian, V.; Armijo, G.; Lamig, L.; Miranda, C.; Lagos, M.; Solari, S.; Guzman, A. M.; Quiroga, T.; Hitschfeld, S.; Riveras, E.; Ferres, M.; Gutierrez, R. A.; Garcia, P.
10.1101/2020.05.07.083048 — molecular biology — Posted on 2020-05-26
976 A simple RNA preparation method for SARS-CoV-2 detection by RT-qPCR
Wozniak, A.; Cerda, A.; Ibarra-Henriquez, C.; Sebastian, V.; Armijo, G.; Lamig, L.; Miranda, C.; Lagos, M.; Solari, S.; Guzman, A. M.; Quiroga, T.; Hitschfeld, S.; Riveras, E.; Ferres, M.; Gutierrez, R. A.; Garcia, P.
10.1101/2020.05.07.083048 — molecular biology — Posted on 2020-05-26
980 Serotonin suppresses slow oscillations by activating somatostatin interneurons via the 5-HT2A receptor
de Filippo, R.; Rost, B.; Stumpf, A.; Cooper, C.; Tukker, J.; Harms, C.; Beed, P.; Schmitz, D.
10.1101/2020.05.26.113373 — neuroscience — Posted on 2020-05-26
981 MINERVA: A facile strategy for SARS-CoV-2 whole genome deep sequencing of clinical samples
Chen, C.; Li, J.; Di, L.; Jing, Q.; Du, P.; Song, C.; Li, J.; Li, Q.; Cao, Y.; Xie, S.; Wu, A. R.; Zeng, H.; Huang, Y.; Wang, J.
10.1101/2020.04.25.060947 — molecular biology — Posted on 2020-05-26
984 Frequency-specific meso-scale structure of spontaneous oscillatory activity in the human brain
Iandolo, R.; Semprini, M.; Mantini, D.; Buccelli, S.; Sona, D.; Avanzino, L.; Chiappalone, M.
10.1101/2020.05.26.114488 — neuroscience — Posted on 2020-05-26
986 A Multi-Objective Genetic Algorithm to Find Active Modules in Multiplex Biological Networks
Novoa del Toro, E. M.; Mezura Montes, E.; Vignes, M.; Magdinier, F.; Tichit, L.; Baudot, A.
10.1101/2020.05.25.114215 — systems biology — Posted on 2020-05-26
987 Single cell resolution regulatory landscape of the mouse kidney highlights cellular differentiation programs and renal disease targets
Miao, Z.; Balzer, M. S.; Ma, Z.; Liu, H.; Wu, J.; Shrestha, R.; Aranyi, T.; Kwan, A.; Kondo, A.; Pontoglio, M.; Kim, J.; Li, M.; Kaestner, K. H.; Susztak, K.
10.1101/2020.05.24.113910 — developmental biology — Posted on 2020-05-26
988 Precise detection of Acrs in prokaryotes using only six features
Dong, C.; Pu, D.-K.; Ma, C.; Wang, X.; Wen, Q.-F.; Zeng, Z.; Guo, F.-B.
10.1101/2020.05.23.112011 — bioinformatics — Posted on 2020-05-26
989 BrphyB is critical for rapid recovery to darkness in mature Brassica rapa leaves
Arsovski, A.; Zemke, J. E.; Hamm, M.; Houston, L.; Romanowski, A.; Halliday, K.; Nesi, N.; Nemhauser, J.
10.1101/2020.05.22.111245 — plant biology — Posted on 2020-05-26
993 Generation of human bronchial organoids for SARS-CoV-2 research
Suzuki, T.; Ito, Y.; Sakai, Y.; Saito, A.; Okuzaki, D.; Motooka, D.; Minami, S.; Kobayashi, T.; Yamamoto, T.; Okamoto, T.; Takayama, K.
10.1101/2020.05.25.115600 — cell biology — Posted on 2020-05-26
1002 An updated staging system for cephalochordate development: one table suits them all
Carvalho, J. E.; Lahaye, F.; Yong, L. W.; Croce, J. C.; Escriva, H.; Yu, J.-K.; Schubert, M.
10.1101/2020.05.26.112193 — developmental biology — Posted on 2020-05-26
1003 Lysine acetylation of TDP-43 drives phase separation and pathological aggregation
Garcia Morato, J.; Hans, F.; von Zweydorf, F.; Feederle, R.; Elsaesser, S. J.; Skodras, A. A.; Gloeckner, C. J.; Neumann, M.; Kahle, P. J.
10.1101/2020.05.26.104356 — cell biology — Posted on 2020-05-26
1006 Median/modal death ages of European males were near-constant for ~30 years.
Clark, J. S. C.; Rydzewska, K.; Podsiadło, K.; van de Wetering, T.; Ciechanowicz, A.
10.1101/2020.05.23.111971 — physiology — Posted on 2020-05-26
1007 Canagliflozin Extends Lifespan in Genetically Heterogeneous Male But Not Female Mice
Miller, R. A.; Harrison, D. E.; Allison, D. B.; Bogue, M.; Diaz, V.; Fernandez, E.; Galecki, A.; Garvey, W. T.; Kumar, N.; Javors, M. A.; Ladies, W. C.; Macchiarini, F.; Nelson, J.; Reifsnyder, P.; Rosenthal, N. A.; Salmon, A. B.; Smith, D. L.; Snyder, J. M.; Lombard, D. B.; Strong, R.
10.1101/2020.05.23.112763 — pathology — Posted on 2020-05-26
1010 A genetically encoded red fluorescence dopamine biosensor enables dual imaging of dopamine and norepinephrine
Nakamoto, C.; Goto, Y.; Tomizawa, Y.; Fukata, Y.; Fukata, M.; Harpsoe, K.; Gloriam, D. E.; Aoki, K.; Takeuchi, T.
10.1101/2020.05.25.115162 — cell biology — Posted on 2020-05-26
1011 Understanding the impact of preprocessing pipelines on neuroimaging cortical surface analyses
Bhagwat, N.; Barry, A.; Dickie, E. W.; Brown, S. T.; Devenyi, G. A.; Hatano, K.; DuPre, E.; Dagher, A.; Chakravarty, M. M.; Greenwood, C. M. T.; Misic, B.; Kennedy, D. N.; Poline, J.-B.
10.1101/2020.05.22.100180 — bioinformatics — Posted on 2020-05-26
1014 Sex and Power: sexual dimorphism in trait variability and its eco-evolutionary and statistical implications
Zajitschek, S. R. K.; Zajitschek, F.; Bonduriansky, R.; Brooks, R. C.; Cornwell, W. K.; Falster, D. S.; Lagisz, M.; Mason, J.; Senior, A.; Noble, D.; Nakagawa, S.
10.1101/2020.05.23.106146 — evolutionary biology — Posted on 2020-05-26
1019 Hypoxia-induced SETX links replication stress with the unfolded protein response
Ramachandran, S.; Ma, T.; Ng, N.; Foskolou, I.; Hwang, M.-S.; Victori, P.; Cheng, W.-C.; Buffa, F. M.; Leszczynska, K.; Gromak, N.; Hammond, E. M.
10.1101/2020.05.24.113548 — cancer biology — Posted on 2020-05-26
1024 Basis of Specificity for a Conserved and Promiscuous Chromatin Remodeling Protein
Donovan, D. A.; Crandall, J. G.; Truong, V. N.; Vaaler, A. L.; Bailey, T. B.; Dinwiddie, D.; McKnight, L. E.; McKnight, J. N.
10.1101/2020.05.25.115584 — molecular biology — Posted on 2020-05-26
1032 Protective Effects of Edaravone Against Hypoxia-Induced Lethality in Mice
Shaki, F.; Mokhtaran, M.; Shamshirian, A.; Eslami, S.; Shamshirian, D.; Ebrahimzadeh, M. A.
10.1101/2020.05.22.111401 — pharmacology and toxicology — Posted on 2020-05-26
1033 ISL2 is an epigenetically silenced tumor suppressor and regulator of metabolism in pancreatic cancer
Tufan, T.; Yang, J.; Tummala, K. S.; Cingoz, H.; Kuscu, C.; Adair, S. J.; Comertpay, G.; Nagdas, S.; Goudreau, B. J.; Lulepay, H. U.; Hsu, K.-l.; Kashatus, D. F.; Bardeesy, N.; Bauer, T. W.; Adli, M.
10.1101/2020.05.23.112839 — molecular biology — Posted on 2020-05-26
1035 State-space Modeling Clarifies Productivity Regime Shifts of Japanese Flying Squid
Nishijima, S.; Kubota, H.; Kaga, T.; Okamoto, S.; Miyahara, H.; Okamura, H.
10.1101/2020.05.22.111088 — ecology — Posted on 2020-05-26
1036 A ubiquitin-based mechanism for the oligogenic inheritance of heterotaxy and heart defects
Kong, J. H.; Young, C. B.; Pusapati, G. V.; Patel, C. B.; Ho, S.; Krishnan, A.; Lin, J.-H. I.; Devine, W.; de Bellaing, A. M.; Athni, T. S.; Aravind, L.; Gunn, T. M.; Lo, C. W.; Rohatgi, R.
10.1101/2020.05.25.113944 — developmental biology — Posted on 2020-05-26
1037 Targeted CRISPR screening identifies PRMT5 as synthetic lethality combinatorial target with gemcitabine in pancreatic cancer cells
Wei, X.; Yang, J.; Adair, S. J.; Kuscu, C.; Lee, K. Y.; Kane, W.; O'Hara, P. E.; Liu, D.; Demirlenk, Y. M.; Habieb, A. H.; Yilmaz, E.; Dutta, A.; Bauer, T.; Adli, M.
10.1101/2020.05.25.112896 — cancer biology — Posted on 2020-05-26
1038 Polymerase Theta Inhibition Kills Homologous Recombination Deficient Tumors
Zhou, J.; Gelot, C.; Pantelidou, C.; Li, A.; Yucel, H.; Davis, R. E.; Farkkila, A.; Kochupurakkal, B.; Syed, A.; Shapiro, G. I.; Tainer, J. A.; Blagg, B. S.; Ceccaldi, R.; D'Andrea, A. D.
10.1101/2020.05.23.111658 — cancer biology — Posted on 2020-05-26
1039 Quantitative analysis questions the role of MeCP2 in alternative splicing
Chhatbar, K.; Cholewa-Waclaw, J.; Shah, R.; Bird, A.; Sanguinetti, G.
10.1101/2020.05.25.115154 — bioinformatics — Posted on 2020-05-26
1043 A selective autophagy pathway for phase separated endocytic protein deposits
Wilfling, F.; Lee, C.-W.; Erdmann, P.; Zheng, Y.; Jentsch, S.; Pfander, B.; Schulman, B. A.; Baumeister, W.
10.1101/2020.05.26.116368 — cell biology — Posted on 2020-05-26
1044 SciSight: Combining faceted navigation and research group detection for COVID-19 exploratory scientific search
Hope, T.; Portenoy, J.; Vasan, K.; Borchardt, J.; Horvitz, E.; Weld, D. S.; Hearst, M. A.; West, J.
10.1101/2020.05.23.112284 — bioinformatics — Posted on 2020-05-26
1049 Children cooperate more successfully with non-kin than with siblings.
Barragan-Jason, G.; Cauchoix, M.; Regnier, A.; Bourjade, M.; Hopfensitz, A.; Chaine, A.
10.1101/2020.05.22.110387 — evolutionary biology — Posted on 2020-05-26
1050 Personalized in-silico drug response prediction based on the genetic landscape of muscle-invasive bladder cancer
Krentel, F.; Singer, F.; Rosano Gonzalez, L.; Gibb, E. A.; Liu, Y.; Davicioni, E.; Keller, N.; Stekhoven, D.; Kruithof-De Julio, M.; Seiler, R.
10.1101/2020.05.22.101428 — bioinformatics — Posted on 2020-05-26
1055 Coupling transcriptomics and behaviour to unveil the olfactory system of Spodoptera exigua larvae
Llopis-Gimenez, A.; Carrasco-Oltra, T.; Jaquin-Joly, E.; Herrero, S.; Crava, C. M.
10.1101/2020.05.22.110155 — ecology — Posted on 2020-05-26
1060 Machine learning analysis of the bleomycin-mouse model reveals the spatial and temporal pulmonary inflammatory fingerprint
Bordag, N.; Biasin, V.; Schnoegl, D.; Francesco, V.; Jandl, K.; Nagy, B. M.; Sharma, N.; Wygrecka, M.; Kwapiszewska, G.; Marsh, L. M.
10.1101/2020.05.22.106690 — immunology — Posted on 2020-05-26
1061 FAM83F regulates canonical Wnt signalling through an interaction with CK1α
Dunbar, K.; Jones, R. A.; Dingwell, K. S.; Macartney, T.; Smith, J. C.; Sapkota, G. P.
10.1101/2020.05.25.114504 — cell biology — Posted on 2020-05-26
1067 Coadaptation of the chemosensory system with voluntary exercise behavior in mice
Nguyen, Q. A. T.; Hillis, D.; Katada, S.; Harris, T.; Pontrello, C.; Garland, T.; Haga-Yamanaka, S.
10.1101/2020.05.24.113506 — animal behavior and cognition — Posted on 2020-05-26
1068 Quantitative secretome analysis establishes the cell type-resolved mouse brain secretome
Tüshaus, J.; Müller, S. A.; Kataka, E. S.; Zaucha, J.; Sebastian Monasor, L.; Su, M.; Güner, G.; Jocher, G.; Tahirovic, S.; Frishman, D.; Simons, M.; Lichtenthaler, S. F.
10.1101/2020.05.22.110023 — neuroscience — Posted on 2020-05-26
1069 Long term sterile immunity induced by an adjuvant-containing live-attenuated AIDS virus
Okamura, T.; Shimizu, Y.; Kanuma, T.; Tsujimura, Y.; Asaka, M. N.; Matsuo, K.; Yamamoto, T.; Yasutomi, Y.
10.1101/2020.05.22.111781 — immunology — Posted on 2020-05-26
1070 SLFN11 captures cancer-immunity interactions associated with platinum sensitivity in ovarian cancer
Winkler, C.; Ferraioli, D.; Garuti, A.; Grillo, F.; Rodriguez-Canales, J.; Ferrando, L.; Chopin, N.; Ray-Coquard, I.; Bedognetti, D.; Ballestrero, A.; Leo, E.; Zoppoli, G.
10.1101/2020.05.22.110593 — cancer biology — Posted on 2020-05-26
1073 Altered kinetics of circulating progenitor cells in cardiopulmonary bypass (CPB) associated vasoplegic patients: An observational study
Nandi, S.; Kumari, C.; Potunuru, U. R.; Nathan, A. A.; Gopal, J.; Menon, G. I.; Siddharthan, R.; Dixit, M.; Thangaraj, P. R.
10.1101/2020.03.11.987099 — physiology — Posted on 2020-05-26
1074 Maintenance of adaptive dynamics in a bottlenecked range-edge population that retained outcrossing
Takou, M.; Hämälä, T.; Koch, E.; Steige, K. A.; Dittberner, H.; Yant, L.; Genete, M.; Sunyaev, S.; Castric, V.; Vekemans, X.; Savolainen, O.; de Meaux, J.
10.1101/709873 — evolutionary biology — Posted on 2020-05-26
1075 Deterministic scRNA-seq of individual intestinal organoids reveals new subtypes and coexisting distinct stem cell pools
Bues, J.; Biocanin, M.; Pezoldt, J.; Dainese, R.; Chrisnandy, A.; Rezakhani, S.; Saelens, W.; Gupta, R.; Russeil, J.; Saeys, Y.; Amstad, E.; Claassen, M.; Lutolf, M.; Deplancke, B.
10.1101/2020.05.19.103812 — bioengineering — Posted on 2020-05-26
1076 Switching secretory pathway direction for organelle acquisition in plants
Kanazawa, T.; Morinaka, H.; Ebine, K.; Shimada, T. L.; Ishida, S.; Minamino, N.; Yamaguchi, K.; Shigenobu, S.; Kohchi, T.; Nakano, A.; Ueda, T.
10.1101/2020.03.02.956961 — plant biology — Posted on 2020-05-26
1077 Human-lineage-specific genomic elements: relevance to neurodegenerative disease and APOE transcript usage
Chen, Z.; Zhang, D.; Reynolds, R. H.; Gustavsson, E. K.; Garcia Ruiz, S.; D'Sa, K.; Fairbrother-Browne, A.; Vandrovcova, J.; Genomics Consortium (IPDGC), I. P. D.; Hardy, J.; Houlden, H.; Gagliano Taliun, S. A.; Botia, J. A.; Ryten, M.
10.1101/2020.04.17.046441 — neuroscience — Posted on 2020-05-26
1078 Mapping the nucleolar proteome reveals a spatiotemporal organization related to intrinsic protein disorder
Stenstrom, L.; Mahdessian, D.; Gnann, C.; Cesnik, A. J.; Ouyang, W.; Leonetti, M.; Uhlen, M.; Cuylen-Haering, S.; Thul, P.; Lundberg, E.
10.1101/2020.01.30.923003 — cell biology — Posted on 2020-05-26
1080 Determining insulin sensitivity from glucose tolerance tests in Iberian and Landrace pigs
Rodriguez-Lopez, J. M.; Lachica, M.; Gonzalez-Valero, L.; Fernandez-Figares, I.
10.1101/2019.12.20.884056 — physiology — Posted on 2020-05-26
1081 Evidence for prescribed NK cell Ly49 developmental pathways in mice
Millan, A. J.; Hom, B. A.; Libang, J. B.; Sindi, S.; Manilay, J. O.
10.1101/2020.05.23.112391 — immunology — Posted on 2020-05-26
1082 NK cells and CTLs are required to clear solid tumor in a novel model of patient-derived-xenograft
Le, D. T.; Burt, B.; Van Buren, G.; Abeynaike, S. A.; Zalfa, C.; Nikzad, R.; Kheradmand, F.; Paust, S.
10.1101/2020.05.24.112722 — immunology — Posted on 2020-05-26
1083 Highly multiplexed molecular and cellular mapping of breast cancer tissue in three dimensions using mass tomography.
Catena, R.; Oezcan, A.; Kuett, L.; Pluess, A.; Schraml, P.; Moch, H.; Consortium, I.; Bodenmiller, B.
10.1101/2020.05.24.113571 — cell biology — Posted on 2020-05-26
1085 High-Efficiency Electroporation of Chytrid Fungi
Swafford, A. J. M.; Hussey, S. P.; Fritz-Laylin, L. K.
10.1101/2020.05.25.114942 — cell biology — Posted on 2020-05-26
1089 Single cell RNA sequencing reveals regulation of fetal ovary development in the monkey (Macaca fascicularis)
Zhao, Z.-H.; Li, C.-Y.; Meng, T.-G.; Wang, Y.; Liu, W.-B.; Li, A.; Cai, Y.-J.; Hou, Y.; Schatten, H.; Wang, Z.-B.; Sun, Q.-Y.; Sun, Q.
10.1101/2020.05.22.110064 — developmental biology — Posted on 2020-05-26
1090 HSP90 inhibition modulates NFB signaling in airway goblet cell metaplasia
Tudas, R. A.; Gannon, R. M.; Thurman, A. L.; Stroik, M. R.; Zabner, J.; Pezzulo, A. A.
10.1101/2020.05.24.113902 — cell biology — Posted on 2020-05-26
1091 Regenerating motor neurons prime muscle stem cells for myogenesis by enhancing protein synthesis and mitochondrial bioenergetics
Choi, J. J.; Shin, E. J.; Han, W. M.; Anderson, S. E.; Mohiuddin, M.; Lee, N. H.; Tran, T.; Nakhai, S.; Jeong, H.; Shcherbina, A.; Jeong, G.; Oh, D. G.; Weinstock, L.; Sankar, S. B.; Ogle, M. E.; Katsimpardi, L.; Rao, T. N.; Wood, L. B.; Aguilar, C. A.; Wagers, A. J.; Jang, Y. C.
10.1101/2020.05.24.113456 — cell biology — Posted on 2020-05-26
1094 Input connectivity reveals additional heterogeneity of dopaminergic reinforcement in Drosophila
Otto, N.; Pleijzier, M. W.; Morgan, I. C.; Edmonson-Stait, A. J.; Heinz, K. J.; Stark, I.; Dempsey, G.; Ito, M.; Kapoor, I.; Hsu, J.; Schlegel, P. M.; Bates, A. S.; Feng, L.; Costa, M.; Ito, K.; Bock, D. D.; Rubin, G. M.; Jefferis, G. S. X. E.; Waddell, S.
10.1101/2020.02.19.952648 — neuroscience — Posted on 2020-05-26
1097 Intercalative DNA binding governs fluorescence enhancement of SYBR Gold
Kolbeck, P. J.; Vanderlinden, W.; Nicolaus, T.; Gebhardt, C.; Cordes, T.; Lipfert, J.
10.1101/2020.05.23.112631 — biophysics — Posted on 2020-05-26
1098 Distinct domain requirements for EAP45 in HIV budding, late endosomal recruitment, and cytokinesis
Meng, B.; Vallejo Ramirez, P. P.; Scherer, K. M.; Bruggeman, E.; Kenyon, J. C.; Kaminski, C. F.; Lever, A. M.
10.1101/2020.05.23.112607 — biophysics — Posted on 2020-05-26
1099 Structural Insights on Fusion Mechanisms of Extracellular Vesicles with Model Plasma Membrane
Perissinotto, F.; Rondelli, V. M.; Senigagliesi, B.; Brocca, P.; Almasy, L.; Bottyan, L.; Merkel, D. G.; Sartori, B.; Amenitsch, H.; Pachler, K.; Mayr, M.; Gimona, M.; Rohde, E.; Casalis, L.; Parisse, P.
10.1101/2020.05.25.110601 — biophysics — Posted on 2020-05-26
1101 The persistence of Nontypeable Haemophilus influenzae fuels airway inflammation
Saliu, F.; Rizzo, G.; Bragonzi, A.; Cariani, L.; Cirillo, D. M.; Colombo, C.; Dacco', V.; Girelli, D.; Rizzetto, S.; Barbara, S.; Cigana, C.; Lore', N. I.
10.1101/2020.05.25.107995 — microbiology — Posted on 2020-05-25
1106 Fecal filtrate transfer protects against necrotizing enterocolitis in preterm pigs
Brunse, A.; Deng, L.; Pan, X.; Hui, Y.; Kot, W.; Nguyen, D. N.; Bojsen-Moller Secher, J.; Nielsen, D. S.; Thymann, T.
10.1101/2020.05.25.114751 — microbiology — Posted on 2020-05-25
1108 Energy efficiency and biological interactions define the core microbiome of deep oligotrophic groundwater
Mehrshad, M.; Lopez-Fernandez, M.; Sundh, J.; Bell, E.; Simone, D.; Buck, M.; Bernier-Latmani, R.; Bertilsson, S.; Dopson, M.
10.1101/2020.05.24.111179 — microbiology — Posted on 2020-05-25
1109 Decoding the architecture of the varicella-zoster virus transcriptome
Braspenning, S. E.; Sadaoka, T.; Breuer, J.; Verjans, G.; Ouwendijk, W. J. D.; Depledge, D. P.
10.1101/2020.05.25.110965 — microbiology — Posted on 2020-05-25
1110 The impact of genetic diversity on gene essentiality within the E. coli species
Rousset, F.; Cabezas Caballero, J.; Piastra-Facon, F.; Fernandez-Rodriguez, J.; Clermont, O.; Denamur, E.; Rocha, E. P. C.; Bikard, D.
10.1101/2020.05.25.114553 — genomics — Posted on 2020-05-25
1111 Functional Organization of the Maternal and Paternal Human 4D Nucleome
Lindsly, S. M.; Jia, W.; Chen, H.; Liu, S.; Ronquist, S.; Chen, C.; Wen, X.; Dotson, G.; Omenn, G. S.; Li, S. C.; Wicha, M.; Rehemtulla, A.; Muir, L.; Rajapakse, I.
10.1101/2020.03.15.992164 — genomics — Posted on 2020-05-25
1113 A standardized head-fixation system for performing large-scale, in-vivo physiological recordings in mice
Groblewski, P.; Sullivan, D.; Lecoq, J.; de Vries, S.; Caldejon, S.; L'Heureux, Q.; Keenan, T.; Roll, K.; Slaughterback, C.; Williford, A.; Farrell, C.
10.1101/2020.01.22.916007 — neuroscience — Posted on 2020-05-25
1114 Ebola and Marburg virus matrix layers are locally ordered assemblies of VP40 dimers
Wan, W.; Clarke, M.; Norris, M.; Kolesnikova, L.; Koehler, A.; Bornholdt, Z.; Becker, S.; Saphire, E. O.; Briggs, J.
10.1101/2020.05.25.114462 — microbiology — Posted on 2020-05-25
1117 Broad-spectrum virucidal activity of bacterial secreted lipases against flaviviruses, SARS-CoV-2 and other enveloped viruses
Yu, X.; Zhang, L.; Tong, L.; Zhang, N.; Wang, H.; Yang, Y.; Shi, M.; Xiao, X.; Zhu, Y.; Wang, P.; Ding, Q.; Zhang, L.; Qin, C.; Cheng, G.
10.1101/2020.05.22.109900 — microbiology — Posted on 2020-05-25
1119 PA-X is an avian virulence factor in H9N2 avian influenza virus
Clements, A. L.; Peacock, T. P.; Sealy, J. E.; Hussain, S.; Sadeyen, J.-R.; Shelton, H.; Digard, P.; Iqbal, M.
10.1101/2020.05.25.114876 — microbiology — Posted on 2020-05-25
1122 A chromosome-level assembly of the cat flea genome uncovers rampant gene duplication and genome size plasticity
Driscoll, T.; Verhoeve, V. I.; Gillespie, J. J.; Johnston, S.; Guillotte, M.; Bankert, K. E.; Rahman, M. S.; Hagen, D.; Elsik, C. G.; Macaluso, K. R.; Azad, A. F.
10.1101/2020.04.14.038018 — genomics — Posted on 2020-05-25
1124 The inhibition of KDM2B promotes the differentiation of basal-like breast cancer cells via the posttranslational destabilization of SLUG.
Fraile, E.-A.; Chavdoula, E.; Laliotis, G. I.; Anastas, V.; Serebrennikova, O.; Paraskevopoulou, M. D.; Tsichlis, P. N.
10.1101/2020.05.21.109819 — cancer biology — Posted on 2020-05-25
1125 Conformational maps of human 20S proteasomes reveal PA28- and immuno-dependant inter-ring crosstalks
Lesne, J.; Locard-Paulet, M.; Parra, J.; Zivkovic, D.; Bousquet, M.-P.; Burlet-Schiltz, O.; Marcoux, J.
10.1101/2020.05.05.078170 — biophysics — Posted on 2020-05-25
1129 Macrophages transfer mitochondria to neurons to resolve inflammatory pain
Raoof, R.; van der Vlist, M.; Willemen, H. L. D. M.; Prado, J.; Versteeg, S.; Vos, M.; Lokhorst, R. E.; Pasterkamp, R. J.; Khoury-Hanold, W.; Meyaard, L.; Eijkelkamp, N.
10.1101/2020.02.12.940445 — neuroscience — Posted on 2020-05-25
1130 Mass Spectrometric detection of SARS-CoV-2 virus in scrapings of the epithelium of the nasopharynx of infected patients via Nucleocapsid N protein
Nikolaev, E. N.; Indeykina, M. I.; Brzhozovskiy, A. G.; Bugrova, A. E.; Kononikhin, A.; Starodubtseva, N. L.; Petrotchenko, E. V.; Kovalev, G. I.; Borchers, C. H.; Sukhikh, G. T.
10.1101/2020.05.24.113043 — molecular biology — Posted on 2020-05-25
1133 Glutamate transporters contain a conserved chloride channel with two hydrophobic gates
Chen, I.; Pant, S.; Wu, Q.; Cater, R.; Sobti, M.; Vandenberg, R.; Stewart, A. G.; Tajkhorshid, E.; Font, J.; Ryan, R. M.
10.1101/2020.05.25.115360 — biophysics — Posted on 2020-05-25
1136 A comparative study of isothermal nucleic acid amplification methods for SARS-CoV-2 detection at point of care
Tran, D. H.; Hoang, Q. C.; Tran, H. T.; Le, U. P.; Do, H. D. K.; Bui, L. M.; Nguyen, D. H.; Hoang, T. L.; Nguyen, T. T. T.; Nguyen, H. A.; Nguyen, T. H.; Cao, M. T.; Vu, V. V.; Phung, H. T. T.
10.1101/2020.05.24.113423 — molecular biology — Posted on 2020-05-25
1137 Methods Matter -- Standard Production Platforms For Recombinant AAV Produce Chemically And Functionally Distinct Vectors
Rumachik, N. G.; Malaker, S. A.; Poweleit, N.; Maynard, L. H.; Adams, C. M.; Leib, R. D.; Cirolia, G.; Thomas, D.; Stamnes, S.; Holt, K.; Sinn, P.; May, A. P.; Paulk, N. K.
10.1101/640169 — molecular biology — Posted on 2020-05-25
1140 Predicting Individual Variability in Task-Evoked Brain Activity in Schizophrenia
Tik, N.; Livny, A.; Gal, S.; Gigi, K.; Tsarfaty, G.; Weiser, M.; Tavor, I.
10.1101/2020.05.25.114603 — neuroscience — Posted on 2020-05-25
1143 Characterization of mWake expression in the murine brain
Bell, B. J.; Wang, A. A.; Kim, D. W.; Blackshaw, S.; Wu, M. N.
10.1101/2020.05.25.114363 — neuroscience — Posted on 2020-05-25
1146 Learning is shaped by abrupt changes in neural engagement
Hennig, J. A.; Oby, E. R.; Golub, M. D.; Bahureksa, L. A.; Sadtler, P. T.; Quick, K. M.; Ryu, S. I.; Tyler-Kabara, E. C.; Batista, A. P.; Chase, S. M.; Yu, B. M.
10.1101/2020.05.24.112714 — neuroscience — Posted on 2020-05-25
1147 Somatostatin neurons of the bed nucleus of stria terminalis enhance associative fear memory consolidation in mice
Bruzsik, B.; Biro, L.; Zelena, D.; Sipos, E.; Szebik, H.; Sarosdi, K. R.; Horvath, O.; Farkas, I.; Csillag, V.; Finszter, C. K.; Mikics, E.; Toth, M.
10.1101/2020.05.22.103481 — neuroscience — Posted on 2020-05-25
1151 Brain orchestration of pregnancy and maternal behavior in mice.
Barriere, D. A.; Ella, A.; Szeremeta, F.; Adriaensen, H.; Meme, W.; Chaillou, E.; Migaud, M.; Meme, S.; Levy, F.; Keller, M.
10.1101/2020.05.23.112045 — neuroscience — Posted on 2020-05-25
1153 Anterior Cingulate Cortex Directs Exploration of Alternative Strategies
Tervo, D. G. R.; P, E. K.; Manakov, M.; Proskurin, M.; Karlsson, M.; Lustig, A.; Behnam, R.; Karpova, A.
10.1101/2020.05.23.098822 — neuroscience — Posted on 2020-05-25
1155 Flow-Mediated Olfactory Communication in Honey Bee Swarms
Nguyen, D. M. T.; Iuzzolino, M. L.; Mankel, A.; Bozek, K.; Stephens, G. J.; Peleg, O.
10.1101/2020.05.23.112540 — animal behavior and cognition — Posted on 2020-05-25
1158 A developmental analysis of juxtavascular microglia dynamics and interactions with the vasculature
Mondo, E.; Becker, S. C.; Kautzman, A. G.; Schifferer, M.; Baer, C. E.; Chen, J.; Huang, E. J.; Simons, M.; Schafer, D. P.
10.1101/2020.05.25.110908 — neuroscience — Posted on 2020-05-25
1159 A neural mechanism of social responsibility
Gaedeke, M.; Willems, T.; Ahmed, O. S.; Weber, B.; Hurlemann, R.; Schultz, J. W.
10.1101/2020.05.25.107300 — neuroscience — Posted on 2020-05-25
1166 Subcellular resolution 3D light field imaging with genetically encoded voltage indicators
Quicke, P.; Howe, C. L.; Song, P.; Verinaz Jadan, H.; Song, C.; Knöpfel, T.; Neil, M.; Dragotti, P. L.; Schultz, S. R.; Foust, A. J.
10.1101/2020.05.22.108191 — neuroscience — Posted on 2020-05-25
1167 Features Of Hippocampal Astrocytic Domains And Their Spatial Relation To Excitatory And Inhibitory Neurons
Refaeli, R.; Doron, A.; Benmelech-Chovav, A.; Groysman, M.; Kreisel, T.; Loewenstein, Y.; Goshen, I.
10.1101/2020.05.25.114348 — neuroscience — Posted on 2020-05-25
1172 Extracting the Dynamics of Behavior in Decision-Making Experiments
Roy, N. A.; Bak, J. H.; The International Brain Lab, ; Akrami, A.; Brody, C. D.; Pillow, J. W.
10.1101/2020.05.21.109678 — neuroscience — Posted on 2020-05-25
1173 A three-dimensional thalamocortical dataset for characterizing brain heterogeneity
Prasad, J. A.; Balwani, A. H.; Johnson, E. C.; Miano, J. D.; Sampathkumar, V.; de Andrade, V.; Fezza, K.; Du, M.; Vescovi, R.; Jacobsen, C.; Kording, K. P.; Gürsoy, D.; Gray-Roncal, W.; Kasthuri, N.; Dyer, E. L.
10.1101/2020.05.22.111617 — neuroscience — Posted on 2020-05-25
1174 MRI-guided histology of TDP-43 knock-in mice implicates parvalbumin interneuron loss, impaired neurogenesis and aberrant neurodevelopment in ALS-FTD
Lin, Z.; Kim, E.; Ahmed, M.; Han, G.; Simmons, C.; Redhead, Y.; Bartlett, J.; Altamira, L. E. P.; Callaghan, I.; White, M.; Singh, N.; Sawiak, S.; Spires-Jones, T.; Vernon, A. C.; Coleman, M.; Green, J. B. A.; Henstridge, C.; Davies, J. S.; Cash, D.; Sreedharan, J.
10.1101/2020.05.24.107177 — neuroscience — Posted on 2020-05-25
1180 Flexible categorization in perceptual decision making
Prat-Ortega, G.; Wimmer, K.; Roxin, A.; de la Rocha, J.
10.1101/2020.05.23.110460 — neuroscience — Posted on 2020-05-25
1181 Dopamine-gated memory selection during slow wave sleep
Isotalus, H. K.; Carr, W. J.; Averill, G. G.; Radtke, O.; Selwood, J.; Williams, R.; Ford, E.; McCullagh, L.; McErlane, J.; O'Donnell, C. K.; Durant, C.; Bartsch, U.; Jones, M. W.; Munoz Neira, C.; Wearn, A. R.; Grogan, J. P.; Coulthard, E. J.
10.1101/2020.05.23.112375 — neuroscience — Posted on 2020-05-25
1182 Decoding music-evoked emotions in the auditory and motor cortex
Putkinen, V.; Nazari-Farsani, S.; Seppala, K.; Karjalainen, T.; Sun, L.; Karlsson, H. K.; Hudson, M.; Heikkila, T. T.; Hirvonen, J.; Nummenmaa, L.
10.1101/2020.05.24.101667 — neuroscience — Posted on 2020-05-25
1185 The floor-plate of His is a non-neuronal electrical conduction pathway
Arulkandarajah, K. H.; Osterstock, G.; Lafont, A.; Le Corronc, H.; Escalas, N.; Corsini, S.; Le Bras, B.; Boeri, J.; Czarnecki, A.; Mouffle, C.; Bullier, E.; Hong, E.; Soula, C.; Legendre, P.; Mangin, J.-M.
10.1101/2020.05.23.111955 — neuroscience — Posted on 2020-05-25
1187 Visual information routes in the posterior dorsal and ventral face network studied with intracranial neurophysiology, and white matter tract endpoints
Babo-Rebelo, M.; Puce, A.; Bullock, D.; Hugueville, L.; Pestilli, F.; Adam, C.; Lehongre, K.; Lambrecq, V.; Dinkelacker, V.; George, N.
10.1101/2020.05.22.102046 — animal behavior and cognition — Posted on 2020-05-25
1188 New oligodendrocytes exhibit more abundant and accurate myelin regeneration than those that survive demyelination
Neely, S. A.; Williamson, J. M.; Klingseisen, A.; Zoupi, L.; Early, J. J.; Williams, A.; Lyons, D. A.
10.1101/2020.05.22.110551 — neuroscience — Posted on 2020-05-25
1189 Microstructural integrity of the major nuclei of the thalamus in Parkinson's disease
Borlase, N.; Myall, D.; Melzer, T. R.; Livingston, L.; Watts, R.; Keenan, R. J.; MacAskill, M.; Anderson, T.; Dalrymple-Alford, J. C.
10.1101/2020.05.21.109660 — neuroscience — Posted on 2020-05-25
1190 UHRF1 drives the poor prognosis associated with RB loss in osteosarcoma
Wu, S. C.; Lopez, J.; Salcido, K.; Zocchi, L.; Wu, J.; Benavente, C.
10.1101/2020.05.24.113647 — cancer biology — Posted on 2020-05-25
1194 Malacological survey in a bottle of water: A comparative study between manual sampling and environmental DNA metabarcoding approaches
Mulero, S.; Toulza, E.; Loisier, A.; Zimmerman, M.; Allienne, J.-F.; Foata, J.; Quilichini, Y.; Pointier, J.-P.; Rey, O.; Boissier, J.
10.1101/2020.05.21.108589 — ecology — Posted on 2020-05-25
1197 Gene regulatory networks controlling differentiation, survival, and diversification of hypothalamic Lhx6-expressing GABAergic neurons.
Kim, D. W.; Liu, K.; Wang, Z. Q.; Zhang, Y. S.; Bathini, A.; Brown, M. P.; Lin, S. H.; Washington, P. W.; Sun, C.; Lindtner, S.; Lee, B.; Wang, H.; Shimogori, T.; Rubenstein, J. L. R.; Blackshaw, S.
10.1101/2020.05.21.106963 — neuroscience — Posted on 2020-05-25
1198 Learning to play the piano with the Supernumerary Robotic 3rd Thumb
Shafti, A.; Haar, S.; Mio Zaldivar, R.; Guilleminot, P.; Faisal, A. A.
10.1101/2020.05.21.108407 — neuroscience — Posted on 2020-05-25
1200 Normal Olfactory Functional Connectivity Despite Life-Long Absence of Olfactory Experiences
Peter, M. G.; Fransson, P.; Martensson, G.; Postma, E. M.; Engstrom Nordin, L.; Westman, E.; Boesveldt, S.; Lundstrom, J. N.
10.1101/2020.05.21.106161 — neuroscience — Posted on 2020-05-25
1204 Potential consequences of the red blood cell storage lesion on cardiac electrophysiology
Reilly, M.; Bruno, C.; Prudencio, T.; Ciccarelli, N.; Guerrelli, D.; Nair, R.; Ramadan, M.; Luban, N.; Posnack, N. G.
10.1101/2020.05.22.111302 — physiology — Posted on 2020-05-25
1208 Heroin self-administration and extinction increases prelimbic cortical astroglia-synapse proximity and alters dendritic spine morphometrics that are reversed by N-acetylcysteine
Siemsen, B. M.; Hooker, K. N.; McFaddin, J. A.; Carpenter, E. A.; Prescott, M. E.; Brock, A. G.; Leath, M. N.; McGinty, J. F.; Scofield, M. D.
10.1101/2020.05.21.108530 — neuroscience — Posted on 2020-05-25
1209 Excitatory-Inhibitory Balance within EEG Microstates and Resting-state fMRI Networks: Assessed via Simultaneous PET-MR-EEG Imaging
Rajkumar, R.; Regio Brambilla, C.; Veselinovic, T.; Bierbrier, J.; Wyss, C.; Ramkiran, S.; Orth, L.; Lang, M.; Rota Kops, E.; Mauler, J.; Scheins, J.; Neumaier, B.; Ermert, J.; Herzog, H.; Langen, K.-J.; Binkofski, F. C.; Lerche, C.; Shah, N. J.; Neuner, I.
10.1101/2020.05.22.109413 — neuroscience — Posted on 2020-05-25
1211 Coupling between slow-waves and sharp-wave ripples organizes distributed neural activity during sleep in humans
Skelin, I.; Zhang, H.; Zheng, J.; Ma, S.; Mander, B. A.; Kim Mcmanus, O.; Vadera, S.; Knight, R. T.; McNaughton, B. L.; Lin, J. J.
10.1101/2020.05.24.113480 — neuroscience — Posted on 2020-05-25
1212 Discovery and characterization of a novel family of prokaryotic nanocompartments involved in sulfur metabolism
Nichols, R. J.; LaFrance, B.; Phillips, N. R.; Oltrogge, L. M.; Valentin-Alvarado, L. E.; Bischoff, A. J.; Nogales, E.; Savage, D.
10.1101/2020.05.24.113720 — biochemistry — Posted on 2020-05-25
1213 AMP-activated-kinase (AMPK) is essential sensor and metabolic regulator of retinal neurons and their integrated metabolism with RPE.
Xu, L.; Brown, E. E.; Keuthan, C. J.; Gubbi, H.; Swaroop, A.; Grellier, E.-K.; Roger, J. E.; Du, J.; Ash, J. D.
10.1101/2020.05.22.109165 — neuroscience — Posted on 2020-05-25
1215 Structural basis of bile acid receptor activation and Gs coupling
Yang, F.; Mao, C.; Guo, L.; Lin, J.; Ming, Q.; Xiao, P.; Wu, X.; Shen, Q.; Guo, S.; Shen, D.-D.; Lu, R.; Zhang, L.; Huang, S.; Ping, Y.; Zhang, C.; Ma, C.; Zhang, K.; Liang, X.; Shen, Y.; Nan, F.; Yi, F.; Luca, V. C.; Zhou, J.; Jiang, C.; Sun, J.; Xie, X.; Yu, X.; Zhang, Y.
10.1101/2020.05.24.104034 — biochemistry — Posted on 2020-05-25
1218 EpiDope: A Deep neural network for linear B-cell epitope prediction
Collatz, M.; Mock, F.; Hoelzer, M.; Barth, E.; Sachse, K.; Marz, M.
10.1101/2020.05.12.090019 — bioinformatics — Posted on 2020-05-25
1221 Heat Shock Protein 27 Immune Complex Upregulates LDLR Expression Thereby Reducing Plasma Cholesterol and Atherogenesis
Chen, Y.-X.; Shi, C.; Deng, J.; Diao, C.; Maarouf, N.; Rosin, M.; Shrivastava, V.; Hu, A.; Bharadwa, S.; Adijiang, A.; Ulke-Lemee, A.; Gwilym, B. L.; Hellmich, A.; Malozzi, C.; Batulan, Z.; Dean, J. L. E.; Ramirez, F. D.; Liu, J.; Gerthoffer, W. T.; O'Brien, E. R.
10.1101/2020.05.21.102350 — pathology — Posted on 2020-05-25
1222 Optogenetic inhibition of colon epithelium reduces hypersensitivity in a mouse model of inflammatory bowel disease
Najjar, S. A.; Ejoh, L. L.; Loeza-Alcocer, E.; Edwards, B. S.; Smith-Edwards, K. M.; Epouhe, A. Y.; Gold, M. S.; Davis, B. M.; Albers, K. M.
10.1101/2020.05.21.107110 — neuroscience — Posted on 2020-05-25
1224 Pituitary stem cells produce paracrine WNT signals to control the expansion of their descendant progenitor cells
Russell, J. P.; Lim, X.; Santambrogio, A.; Yianni, V.; Kemkem, Y.; Wang, B.; Fish, M.; Haston, S.; Grabek, A.; Hallang, S.; Lodge, E. J.; Patist, A. L.; Schedl, A.; Mollard, P.; Nusse, R.; Andoniadou, C. L.
10.1101/2020.05.22.107045 — developmental biology — Posted on 2020-05-25
1225 Natural Genetic Variation in Drosophila melanogaster Reveals Genes Associated with Coxiella burnetii Infection
Guzman, R. M.; Howard, Z. P.; Liu, Z.; Oliveira, R. D.; Massa, A. T.; Omsland, A.; White, S.; Goodman, A. G.
10.1101/2020.05.21.109371 — genetics — Posted on 2020-05-25
1226 Decreased miR-24-3p potentiates DNA damage responses and increases susceptibility to COPD
Nouws, J.; Wan, F.; Finnemore, E.; Roque, W.; Kim, S.; Bazan, I.; Li, C.-x.; Skold, M.; Yan, X.; Neumeister, V.; Britto, C. J.; Bindra, R.; Wheelock, A.; Gomez-Villalobos, J.; Kaminski, N.; Lee, P. J.; Sauler, M.
10.1101/2020.05.22.108688 — cell biology — Posted on 2020-05-25
1228 A proteogenomics workflow to uncover the world of small proteins in Staphylococcus aureus
Fuchs, S.; Kucklick, M.; Lehmann, E.; Beckmann, A.; Wilkens, M.; Kolte, B.; Mustafayeva, A.; Ludwig, T.; Diwo, M.; Wissing, J.; Jaensch, L.; Ahrens, C. H.; Ignatova, Z.; Engelmann, S.
10.1101/2020.05.25.114132 — genomics — Posted on 2020-05-25
1230 Variable Number Tandem Repeats mediate the expression of proximal genes
Bakhtiari, M.; Park, J.; Ding, Y.-C.; Shleizer-Burko, S.; Neuhausen, S. L.; Halldorsson, B. V.; Stefansson, K.; Gymrek, M.; Bafna, V.
10.1101/2020.05.25.114082 — genomics — Posted on 2020-05-25
1233 Genetic Risk Scores for Cardiometabolic Traits in Sub-Saharan African Populations
Ekoru, K.; Adeyemo, A. A.; Chen, G.; Doumatey, A. P.; Zhou, J.; Bentley, A. R.; Shriner, D.; Rotimi, C. N.
10.1101/2020.05.21.109199 — genomics — Posted on 2020-05-25
1235 Network Preservation Reveals Shared and Unique Biological Processes Associated with Chronic Alcohol Abuse in NAc and PFC.
Vornholt, E.; Mamdani, M.; Drake, J.; McMichael, G.; Taylor, Z. N.; Bacanu, S.-A.; Miles, M. F.; Vladimirov, V. I.
10.1101/2020.05.21.108621 — genomics — Posted on 2020-05-25
1241 A Two-Part Strategy using Genomic Selection in Hybrid Crop Breeding Programs
Powell, O. M.; Gaynor, R. C.; Gorjanc, G. M.; Werner, C. R.; Hickey, J. M.
10.1101/2020.05.24.113258 — genetics — Posted on 2020-05-25
1242 The comprehensive genetic architecture of brain white matter
Zhao, B.; Li, T.; Yang, Y.; Wang, X.; Luo, T.; Shan, Y.; Zhu, Z.; Xiong, D.; Li, Y.; Stein, J. L.; Zhu, H.
10.1101/2020.05.23.112409 — genetics — Posted on 2020-05-25
1243 Bi-allelic variants in TSPOAP1, encoding the active zone protein RIMBP1, cause autosomal recessive dystonia
Mencacci, N. E.; Brockmann, M. M.; Dai, J.; Pajusalu, S.; Atasu, B.; Gonzalez-Latapi, P.; Patzke, C.; Schwake, M.; Tucci, A.; Pittmann, A.; Simon-Sanchez, J.; Carvill, G.; Balint, B.; Wiethoff, S.; Warner, T. W.; Papandreou, A.; Soo, A.; Rein, R.; Kadastik-Eerme, L.; Puusepp, S.; Reinson, K.; Tomberg, T.; Pino, G.; Campos, J.; Hanagasi, H.; Gasser, T.; Bhatia, K.; Kurian, M.; Lohmann, E.; Ounap, K.; Rosenmund, C.; Sudhof, T.; Wood, N. W.; Krainc, D.; Acuna, C.
10.1101/2020.05.24.086215 — genetics — Posted on 2020-05-25
1245 Novel missense mutation E585K in retinitis pigmentosa leads to compromised RPGR splicing diversity
Liu, Y.; Wan, J.-F.; Ren, C.-Y.; Xu, Z.-H.; Pan, X.-B.; Pan, J.-Q.; Gao, N.-N.; Liu, S.-Q.; Zhang, J.-L.; Yao, Q.-H.; Wang, J.-H.; Li, E.-M.; Rao, J.-H.; Hou, P.; Chen, J.-H.
10.1101/2020.05.22.109884 — genetics — Posted on 2020-05-25
1247 Relationship of DUX4 and target gene expression in FSHD myocytes
Chau, J.; Kong, X.; Nguyen, N. V.; Williams, K.; Tawil, R.; Kiyono, T.; Mortazavi, A.; Yokomori, K.
10.1101/2020.05.24.109710 — genetics — Posted on 2020-05-25
1258 Late Quaternary habitat suitability models for chimpanzees (Pan troglodytes) since the Last Interglacial (120,000 BP)
Barratt, C. D.; Lester, J. D.; Gratton, P.; Onstein, R. E.; Kalan, A. K.; McCarthy, M. S.; Bocksberger, G.; White, L. C.; Vigilant, L.; Dieguez, P.; Boesch, C.; Arandjelovic, M.; Kuehl, H.
10.1101/2020.05.15.066662 — ecology — Posted on 2020-05-25
1260 Integrated cross-study datasets of genetic dependencies in cancer
Pacini, C.; Dempster, J. M.; Goncalves, E.; Najgebauer, H.; Karakoc, E.; van der Meer, D.; Barthorpe, A.; Lightfoot, H.; Jaaks, P.; McFarland, J. M.; Garnett, M.; Tsherniak, A.; Iorio, F.
10.1101/2020.05.22.110247 — bioinformatics — Posted on 2020-05-25
1261 In silico detection of SARS-CoV-2 specific B-cell epitopes and validation in ELISA for serological diagnosis of COVID-19
Phan, I. Q.; Subramanian, S.; Kim, D.; Carter, L.; King, N.; Anishchenko, I.; Barrett, L. K.; Craig, J. K.; Tillery, L.; Shek, R.; Harrington, W. E.; Koelle, D. M.; Wald, A.; Boonyaratanakornkit, J.; Isoherranen, N.; Greninger, A. L.; Jerome, K. R.; Chu, H.; Staker, B.; Myler, P. J.; Van Voorhis, W. C.
10.1101/2020.05.22.111526 — bioinformatics — Posted on 2020-05-25
1262 Cold-induced hyperphagia requires AgRP-neuron activation in mice
Deem, J.; Faber, C. L.; Pedersen, C.; Phan, B. A.; Larsen, S. A.; Ogimoto, K.; Nelson, J. T.; Damian, V.; Tran, M. A.; Palmiter, R.; Kaiyala, K. J.; Scarlett, J. M.; Bruchas, M.; Schwartz, M. W.; Morton, G. J.
10.1101/2020.05.21.107896 — neuroscience — Posted on 2020-05-25
1263 Shank2 expression identifies a subpopulation of glycinergic interneurons involved in nociception and altered in an autism mouse model
olde Heuvel, F.; Ouali-Alami, N.; Wilhelm, H.; Deshpande, D.; Khatamsaz, E.; Catanese, A.; Woelfle, S.; Schoen, M.; Jain, S.; Grabrucker, S.; Ludolph, A. C.; Verpelli, C.; Michaelis, J.; Boeckers, T.; Roselli, F.
10.1101/2020.05.24.112052 — neuroscience — Posted on 2020-05-25
1264 Non-CG methylation and multiple epigenetic layers associate child abuse with immune and small GTPase dysregulation
Lutz, P.-E.; Chay, M.-A.; Pacis, A.; Chen, G. G.; Aouabed, Z.; Maffioletti, E.; Theroux, J.-F.; Grenier, J.-C.; Yang, J.; Aguirre, M.; Ernst, C.; Redensek, A.; van Kempen, L. C.; Yalcin, I.; Kwan, T.; Mechawar, N.; Pastinen, T.; Turecki, G.
10.1101/501239 — neuroscience — Posted on 2020-05-25
1270 N-type calcium channels control GABAergic transmission in brain areas related to fear and anxiety
Blazon, M.; LaCarubba, B.; Bunda, A.; Czepiel, N.; Mallat, S.; Londrigan, L.; Andrade, A.
10.1101/2020.05.24.113712 — neuroscience — Posted on 2020-05-25
1271 A workflow for accurate metabarcoding using nanopore MinION sequencing
Baloglu, B.; Chen, Z.; Elbrecht, V.; Braukmann, T.; MacDonald, S.; Steinke, D.
10.1101/2020.05.21.108852 — bioinformatics — Posted on 2020-05-25
1273 Immunoglobulin T genes in Neopterygii
Mirete-Bachiller, S.; Olivieri, D. N.; Gambon-Deza, F.
10.1101/2020.05.21.108993 — immunology — Posted on 2020-05-24
1275 A bipartite element with allele-specific functions safeguards DNA methylation imprints at the Dlk1-Dio3 locus
Aronson, B. E.; Scourzic, L.; Shah, V.; Swanzey, E.; Kloetgen, A.; Polyzos, A.; Sinha, A.; Azziz, A.; Caspi, I.; Li, J.; Pelham-Webb, B.; Wichterle, H.; Tsirigos, A.; Stadtfeld, M.; Apostolou, E.
10.1101/2020.05.22.103796 — developmental biology — Posted on 2020-05-24
1276 Development of novel apoptosis-assisted lung tissue decellularization methods
Song, Y. H.; Maynes, M.; Hlavac, N.; Visosevic, D.; Daramola, K.; Porvasnik, S. L.; Schmidt, C. E.
10.1101/2020.05.21.109173 — bioengineering — Posted on 2020-05-25
1278 Activation of amino acid metabolic program in response to impaired glycolysis in cardiac HIF1 deficient mice
Menendez-Montes, I.; Escobar, B.; Gomez, M. J.; Albendea-Gomez, T.; Palacios, B.; Bonzon, E.; Alonso, A. V.; Ferrarini, A.; Gimenez-Borreguero, L. J.; Vazquez, J.; Martin-Puig, S.
10.1101/2020.05.23.111674 — developmental biology — Posted on 2020-05-24
1279 Structural visualization of septum formation in Staphylococcus warneri using atomic force microscopy
Su, H.-N.; Li, K.; Yuan, X.-X.; Zhang, M.-Y.; Liu, S.-M.; Chen, X.-L.; Liu, L.-N.; Zhang, Y.-Z.
10.1101/2020.05.24.113035 — biophysics — Posted on 2020-05-24
1281 Brain tissue transcriptomic analysis of SIV-infected macaques identifies Poly (ADP-ribose) polymerases (PARPs) as potential biomarkers for neuropathogenesis.
Mavian, C. N.; Ramirez-Mata, A. S.; Dollar, J. J.; Nolan, D. J.; Rich, S. N.; White, K.; Rife Magalis, B.; Cash, M. N.; Marini, S.; Prosperi, M.; Moraga Amador, D.; Riva, A.; Williams, K. C.; Salemi, M.
10.1101/2020.05.21.109140 — pathology — Posted on 2020-05-24
1282 Hidden features of the malaria vectormosquito, Anopheles stephensi ,revealed by a high-quality referencegenome
Chakraborty, M.; Ramaiah, A.; Adolfi, A.; Halas, P.; Kaduskar, B.; Ngo, L. T.; Jayaprasad, S.; Paul, K.; Whadgar, S.; Srinivasan, S.; Subramani, S.; Bier, E.; James, A.; Emerson, J. J.
10.1101/2020.05.24.113019 — genomics — Posted on 2020-05-24
1286 Treatment with valproate downregulates the Agtr2 mRNA in rat lungs
Seppa, K.; Terasmaa, A.; Jagomäe, T.; Innos, J.; Vasar, E.; Plaas, M.
10.1101/2020.05.21.108399 — molecular biology — Posted on 2020-05-24
1287 In vitro evolution of colistin resistance in the Klebsiella pneumoniae complex follows multiple evolutionary trajectories with variable effects on fitness and virulence characteristics.
Janssen, A. B.; Doorduijn, D. J.; Mills, G.; Rogers, M. R. C.; Bonten, M.; Rooijakkers, S.; Willems, R. J. L.; Bengoechea, J. A.; van Schaik, W.
10.1101/2020.05.24.112334 — microbiology — Posted on 2020-05-24
1289 Discovery of a novel simian pegivirus in common marmosets (Callithrix jacchus) with lymphocytic enteritis
Heffron, A. S.; Lauck, M.; Somsen, E. D.; Townsend, E. C.; Bailey, A. L.; Eickhoff, J. C.; Newman, C. M.; Kuhn, J.; Mejia, A.; Simmons, H. A.; OConnor, D.
10.1101/2020.05.24.113662 — microbiology — Posted on 2020-05-24
1290 Nanopore sequencing enables comprehensive transposable element epigenomic profiling
Ewing, A. D.; Smits, N.; Sanchez-Luque, F. J.; Faivre, J.; Brennan, P. M.; Cheetham, S. W.; Faulkner, G. J.
10.1101/2020.05.24.113068 — genomics — Posted on 2020-05-24
1292 Comparison of induced neurons reveals slower structural and functional maturation in humans than in apes
Schoernig, M.; Ju, X.; Fast, L.; Weigert, A.; Schaffer, T.; Ebert, S.; Treutlein, B.; Nadif Kasri, N.; Peter, B.; Hevers, W.; Taverna, E.
10.1101/2020.05.21.094912 — evolutionary biology — Posted on 2020-05-24
1293 MicroRNAs Restrain Proliferation in BRAFV600E Melanocytic Nevi
McNeal, A. S.; Belote, R. L.; Zeng, H.; Barker, K.; Torres, R.; Shain, A. H.; Andtbacka, R. H.; Holmen, S. L.; Lum, D. H.; McCalmont, T.; VanBrocklin, M. W.; Wei, M. L.; Lang, U. E.; Judson-Torres, R. L.
10.1101/2020.05.21.109397 — cancer biology — Posted on 2020-05-24
1297 Ketamine restores escape behavior by re-engaging dopamine systems to drive cortical spinogenesis
Wu, M.; Minkowicz, S.; Dumrongprechachan, V.; Hamilton, P.; Xiao, L.; Kozorovitskiy, Y.
10.1101/2020.03.11.987818 — neuroscience — Posted on 2020-05-24
1306 The ORF8 Protein of SARS-CoV-2 Mediates Immune Evasion through Potently Downregulating MHC-I
Zhang, Y.; Zhang, J.; Chen, Y.; Luo, B.; Yuan, Y.; Huang, F.; Yang, T.; Yu, F.; Liu, J.; Liu, B.; Song, Z.; Chen, J.; Pan, T.; Zhang, X.; Li, Y.; Li, R.; Huang, W.; Xiao, F.; Zhang, H.
10.1101/2020.05.24.111823 — microbiology — Posted on 2020-05-24
1307 Evidence of natural selection in human complex phenotypes from GWAS summary statistics
Holland, D.; Frei, O.; Desikan, R.; Fan, C. C.; Shadrin, A.; Smeland, O.; Andreassen, O. A.; Dale, A.
10.1101/705285 — genomics — Posted on 2020-05-24
1312 Stable unmethylated DNA demarcates expressed genes and their cis-regulatory space in plant genomes
Crisp, P. A.; Marand, A. P.; Noshay, J. M.; Zhou, P.; Lu, Z.; Schmitz, R. J.; Springer, N. M.
10.1101/2020.05.21.109744 — genomics — Posted on 2020-05-24
1313 Multiple domains in ARHGAP36 regulate PKA degradation and Gli activation
Nano, P. R.; Kudo, T.; Mooney, N. A.; Ni, J.; Demeter, J.; Jackson, P. K.; Chen, J. K.
10.1101/2020.05.14.094961 — cell biology — Posted on 2020-05-24
1318 Tripartite Inhibition of SRC-WNT-PKC Signalling Consolidates Human Naive Pluripotency
Bayerl, J.; Ayyash, M.; Shani, T.; Manor, Y.; Gafni, O.; Kalma, Y.; Aguilera-Castrejon, A.; Zerbib, M.; Amir, H.; Sheban, D.; Geula, S.; Mor, N.; Weinberger, L.; Krupalnik, V.; Oldak, B.; Livnat, N.; Tarazi, S.; Tawil, S.; Lasman, L.; Hanna, S.; Novershtern, N.; Ben-Yosef, D.; Viukov, S.; Hanna, J. H.
10.1101/2020.05.23.112433 — developmental biology — Posted on 2020-05-24
1320 Frizzled-dependent Planar Cell Polarity without Wnt Ligands
Yu, J. J. S.; Maugarny-Cales, A.; Pelletier, S.; Alexandre, C.; Bellaiche, Y.; Vincent, J.-P.; McGough, I. J.
10.1101/2020.05.23.108977 — developmental biology — Posted on 2020-05-24
1322 Winner-Takes-All Resource Competition Redirects Cascading Cell Fate Transitions
Zhang, R.; Goetz, H.; Melendez-Alvarez, J.; Li, J.; Ding, T.; Wang, X.; Tian, X.
10.1101/2020.05.23.103259 — synthetic biology — Posted on 2020-05-24
1324 Profiling of Human Gut Virome with Oxford Nanopore Technology
Cao, J.; Zhang, Y.; Dai, M.; Xu, J.; Chen, L.; Zhang, F.; Zhao, N.; Wang, J.
10.1101/2020.02.03.933077 — bioinformatics — Posted on 2020-05-24
1325 UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFRsignaling
TORRINO, S.; TIROILLE, V.; DOLFI, B.; DUFIES, M.; HINAULT, C.; BONESSO, L.; DAGNINO, S.; UHLER, J. P.; IRONDELLE, M.; GAY, A.-S.; FLEURIOT, L.; Debayle, D.; LACAS-GERVAIS, S.; CORMONT, M.; BERTERO, T.; BOST, F.; GILLERON, J.; CLAVEL, S.
10.1101/2020.05.20.105775 — cell biology — Posted on 2020-05-24
1326 Arabidopsis cell wall composition determines disease resistance specificity and fitness
Molina, A.; Miedes, E.; Bacete, L.; Rodriguez, T.; Melida, H.; Denance, N.; Sanchez-Vallet, A.; Riviere, M.-P.; Lopez, G.; Freydier, A.; Barlet, X.; Pattathil, S.; Hahn, M. G.; Goffner, D.
10.1101/2020.05.21.105650 — plant biology — Posted on 2020-05-24
1327 Single cell RNA-seq analysis reveals compartment-specific heterogeneity and plasticity of microglia
Zheng, J.; Ru, W.; Adolacion, J. R.; Spurgat, M. S.; Liu, X.; Yuan, S.; Liang, R. X.; Dong, J.; Potter, A.; Potter, S. S.; Varadarajan, N.; Tang, S.-J.
10.1101/2020.03.10.985895 — neuroscience — Posted on 2020-05-24
1330 Mechanical cell competition in heterogeneous epithelial tissues
Murphy, R. J.; Buenzli, P. R.; Baker, R. E.; Simpson, M. J.
10.1101/869495 — biophysics — Posted on 2020-05-24
1334 NTR 2.0: a rationally-engineered prodrug converting enzyme with substantially enhanced efficacy for targeted cell ablation
Sharrock, A. v.; Mulligan, T. S.; Hall, K. R.; Williams, E. M.; White, D. T.; Zhang, L.; Matthews, F.; Nimmagadda, S.; Washington, S.; Le, K.; Meir-Levi, D.; Cox, O. L.; Saxena, M. T.; Calof, A.; Lopez-Burks, M. E.; Lander, A. D.; Ding, D.; Ji, H.; Ackerley, D. F.; Mumm, J. S.
10.1101/2020.05.22.111427 — cell biology — Posted on 2020-05-24
1337 Intravital imaging reveals cell cycle-dependent satellite cell migration during muscle regeneration.
Konagaya, Y.; Takakura, K.; Sogabe, M.; Bisaria, A.; Liu, C.; Meyer, T.; Sehara-Fujisawa, A.; Matsuda, M.; Terai, K.
10.1101/2020.05.22.111138 — cell biology — Posted on 2020-05-24
1338 Proofreading through spatial gradients
Galstyan, V.; Husain, K.; Xiao, F.; Murugan, A.; Phillips, R.
10.1101/2020.05.23.112664 — biophysics — Posted on 2020-05-24
1339 Use of the Polo-like kinase 4 (PLK4) inhibitor centrinone to investigate intracellular signaling networks using SILAC-based phosphoproteomics
Byrne, D. P.; Clarke, C. J.; Brownridge, P.; Kalyuzhnyy, A.; Perkins, S.; Campbell, A.; Mason, D.; Jones, A. R.; Eyers, P. A.; Eyers, C. E.
10.1101/2020.05.22.110767 — biochemistry — Posted on 2020-05-24
1340 Proliferation is a requirement for differentiation of oligodendrocyte progenitor cells during CNS remyelination
Foerster, S.; Neumann, B.; McClain, C.; Di Canio, L.; Chen, C.; Reich, D.; Simons, B. D.; Franklin, R.
10.1101/2020.05.21.108373 — neuroscience — Posted on 2020-05-24
1341 Inhibition of Osteoclast Differentiation and Activation by Leukotriene B4 Loaded in Microspheres
Lorencetti-Silva, F.; Manfrin Arnez, M. F.; Thome, J. P. Q.; Carvalho, F. K.; Faccioli, L. H.; Paula-Silva, F. W. G.
10.1101/2020.05.22.111633 — cell biology — Posted on 2020-05-24
1343 Improvements on marker-free images alignment for electron tomography
Sorzano, C. O. S.; de Isidro-Gomez, F.; Fernandez-Gimenez, E.; Herreros, D.; Marco, S.; Carazo, J. M.; Messaoudi, C.
10.1101/2020.05.22.110445 — molecular biology — Posted on 2020-05-24
1344 High-Throughput Human Primary Cell-Based Airway Model for Evaluating Influenza, Coronavirus, or other Respiratory Viruses in vitro
Gard, A. L.; Maloney, R.; Cain, B. P.; Miller, C. R.; Luu, R. J.; Coppeta, J. R.; Liu, P.; Wang, J. P.; Azizgolshani, H.; Fezzie, R. F.; Balestrini, J. L.; Isenberg, B. C.; Finberg, R. W.; Borenstein, J. T.
10.1101/2020.05.23.112797 — microbiology — Posted on 2020-05-23
1349 A viral genome packaging motor transitions between cyclic and helical symmetry to translocate dsDNA
Woodson, M.; Pajak, J.; Zhao, W.; Zhang, W.; Arya, G.; White, M. A.; Jardine, P. J.; Morais, M. C.
10.1101/2020.05.23.112524 — biophysics — Posted on 2020-05-23
1350 Nanaerobic growth enables direct visualization of dynamic cellular processes in human gut symbionts
Garcia-Bayona, L.; Coyne, M. J.; Hantman, N.; Montero-Llopis, P.; Von, S.; Ito, T.; Malamy, M.; Basler, M.; Barquera, B.; Comstock, L. E.
10.1101/2020.05.22.111492 — microbiology — Posted on 2020-05-23
1353 The stringent stress response controls proteases and global regulators under optimal growth conditions in Pseudomonas aeruginosa
Pletzer, D.; Blimkie, T. M.; Wolfmeier, H.; Li, Y.; Baghela, A.; Lee, A. H.; Falsafi, R.; Hancock, R. E. W.
10.1101/2020.05.23.112573 — microbiology — Posted on 2020-05-23
1354 High burden of Mycoplasma genitalium and other reproductive tract infections among pregnant women in Papua New Guinea
Scoullar, M. J. L.; Boeuf, P.; Peach, E.; Fidelis, R.; Tokmun, K.; Melepia, P.; Elijah, A.; Bradshaw, C. S.; Fehler, G.; Siba, P. M.; Erskine, S.; Mokany, E.; Kennedy, E.; Umbers, A. J.; Luchters, S.; Robinson, L. J.; Wong, N. C.; Vallely, A.; Badman, S. G.; Vallely, L. M.; Fowkes, F. J. I.; Morgan, C.; Pomat, W.; Crabb, B. S.; Beeson, J. G.
10.1101/2020.05.22.109983 — microbiology — Posted on 2020-05-23
1355 smORFer: a modular algorithm to detect small ORFs in prokaryotes
Bartholomaus, A.; Kolte, B.; Mustafayeva, A.; Goebel, I.; Fuchs, S.; Engelmann, S.; Ignatova, Z.
10.1101/2020.05.21.109181 — bioinformatics — Posted on 2020-05-23
1357 Biophysical modeling of the SARS-CoV-2 viral cycle reveals ideal antiviral targets
Castle, B. T.; Dock, C.; Hemmat, M.; Kline, S.; Tignanelli, C.; Rajasingham, R.; Masopust, D.; Provenzano, P.; Langlois, R.; Schacker, T.; Haase, A.; Odde, D. J.
10.1101/2020.05.22.111237 — systems biology — Posted on 2020-05-23
1359 Intestinal inflammation modulates the expression of ACE2 and TMPRSS2 and potentially overlaps with the pathogenesis of SARS-CoV-2 related disease
Suarez-Farinas, M.; Tokuyama, M.; Wei, G.; Huang, R.; Livanos, A.; Jha, D.; Levescot, A.; Kosoy, R.; Irizar, H.; Cording, S.; Wang, W.; Ungaro, R.; Di Narzo, A.; Martinez, G.; Suprun, M.; Corley, M. J.; Stojmirovic, A.; Houten, S.; Curran, M.; Brodmerkel, C.; Perrigoue, J.; Friedman, J. R.; Hao, K.; Schadt, E. E.; Zhu, J.; Ko, H. M.; Cho, J.; Dubinsky, M. C.; Sands, B. E.; Ndhlovu, L.; Cerf-Bensusan, N.; Kasarskis, A.; Colombel, J.-F.; Harpaz, N.; Argmann, C.; Mehandru, S.
10.1101/2020.05.21.109124 — immunology — Posted on 2020-05-23
1360 Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions
Mathew, D.; Giles, J. R.; Baxter, A. E.; Greenplate, A. R.; Wu, J. E.; Alanio, C.; Oldridge, D. A.; Kuri-Cervantes, L.; Pampena, M. B.; D'Andrea, K.; Manne, S.; Chen, Z.; Huang, Y. J.; Reilly, J. P.; Weisman, A. R.; Ittner, C. A. G.; Kuthuru, O.; Dougherty, J.; Nzingha, K.; Han, N.; Kim, J.; Pattekar, A.; Goodwin, E. C.; Anderson, E. M.; Weirick, M. E.; Gouma, S.; Arevalo, C. P.; Bolton, M. J.; Chen, F.; Lacey, S. F.; Hensley, S. E.; Apostolidis, S.; Huang, A. C.; Vella, L. A.; UPenn COVID Processing Unit, ; Betts, M. R.; Meyer, N. J.; Wherry, E. J.
10.1101/2020.05.20.106401 — immunology — Posted on 2020-05-23
1361 The emergence of SARS-CoV-2 in Europe and the US
Worobey, M.; Pekar, J.; Larsen, B. B.; Nelson, M. I.; Hill, V.; Joy, J. B.; Rambaut, A.; Suchard, M. A.; Wertheim, J. O.; Lemey, P.
10.1101/2020.05.21.109322 — genetics — Posted on 2020-05-23
1362 Lung epithelial stem cells express SARS-CoV-2 entry factors: implications for COVID-19
Valyaeva, A. A.; Zharikova, A. A.; Kasianov, A. S.; Vassetzky, Y. S.; Sheval, E. V.
10.1101/2020.05.23.107334 — cell biology — Posted on 2020-05-23
1363 In silico detection of SARS-CoV-2 specific B-cell epitopes and validation in ELISA for serological diagnosis of COVID-19
Phan, I. Q.; Subramanian, S.; Kim, D.; Carter, L.; King, N.; Anishchenko, I.; Barrett, L. K.; Craig, J. K.; Tillery, L.; Shek, R.; Harrington, W. E.; Koelle, D. M.; Wald, A.; Boonyaratanakornkit, J.; Isoherranen, N.; Greninger, A. L.; Jerome, K. R.; Chu, H.; Staker, B.; Myler, P. J.; Van Voorhis, W. C.
10.1101/2020.05.22.111526 — bioinformatics — Posted on 2020-05-23
1364 Targeting the SARS-CoV-2 Main Protease to Repurpose Drugs for COVID-19
Vatansever, E. C.; Yang, K.; Kratch, K. C.; Drelich, A.; Cho, C.-C.; Mellot, D. M.; Xu, S.; Tseng, C.-T. K.; Liu, W. R.
10.1101/2020.05.23.112235 — pharmacology and toxicology — Posted on 2020-05-23
1365 A Modular Microarray Imaging System for Highly Specific COVID-19 Antibody Testing
Hedde, P. N.; Abram, T. J.; Jain, A.; Nakajima, R.; Ramiro de Assis, R.; Pearce, T.; Jasinskas, A.; Toosky, M. N.; Khan, S.; Felgner, P. L.; Gratton, E.; Zhao, W.
10.1101/2020.05.22.111518 — microbiology — Posted on 2020-05-23
1366 T cells Mediate Progression of Load-Induced Osteoarthritis
Wheeler, T. A.; Antoinette, A. Y.; Kim, M. J.; van der Meulen, M. C. H.; Singh, A.
10.1101/2020.05.20.106435 — immunology — Posted on 2020-05-23
1367 Predicting wildlife hosts of betacoronaviruses for SARS-CoV-2 sampling prioritization
Becker, D.; Albery, G. F.; Sjodin, A. R.; Poisot, T.; Dallas, T.; Eskew, E. A.; Farrell, M. J.; Guth, S.; Han, B. A.; Simmons, N. B.; Carlson, C. J.
10.1101/2020.05.22.111344 — ecology — Posted on 2020-05-23
1368 Age-related expression of SARS-CoV-2 priming protease TMPRSS2 in the developing lung
Schuler, B. A.; Habermann, A. C.; Plosa, E. J.; Taylor, C. J.; Jetter, C. S.; Kapp, M. E.; Benjamin, J.; Gulleman, P.; Nichols, D. S.; Braunstein, L. Z.; Koval, M. H.; Guttentag, S. H.; Blackwell, T. S.; Vanderbilt COVID-19 Consortium Cohort, ; Webber, S. A.; Banovich, N.; Kropski, J. A.; Sucre, J. M.; HCA Lung Biological Network,
10.1101/2020.05.22.111187 — developmental biology — Posted on 2020-05-23
1370 Neural Stimulation in vitro and in vivo by Photoacoustic Nanotransducers
Huang, Y.; Jiang, Y.; Luo, X.; Wu, J.; Zong, H.; Shi, L.; Cheng, R.; Jiang, S.; Jia, X.; Mei, J.; Man, H.; Cheng, J.-X.; Yang, C.
10.1101/2020.05.20.106898 — neuroscience — Posted on 2020-05-23
1371 Systemic and mucosal antibody secretion specific to SARS-CoV-2 during mild versus severe COVID-19
Cervia, C.; Nilsson, J.; Zurbuchen, Y.; Valaperti, A.; Schreiner, J.; Wolfensberger, A.; Raeber, M. E.; Adamo, S.; Emmenegger, M.; Hasler, S.; Bosshard, P. P.; De Cecco, E.; Baechli, E.; Rudiger, A.; Stuessi-Helbling, M.; Huber, L. C.; Zinkernagel, A. S.; Schaer, D. J.; Aguzzi, A.; Held, U.; Probst-Mueller, E.; Rampini, S. K.; Boyman, O.
10.1101/2020.05.21.108308 — immunology — Posted on 2020-05-23
1373 Biomimetic sponges improve muscle structure and function following volumetric muscle loss
Haas, G.; Dunn, A.; Madsen, J.; Genovese, P.; Lin, A.; Chauvin, H.; Au, J.; Paoli, A.; Garg, K.
10.1101/2020.05.20.106823 — bioengineering — Posted on 2020-05-23
1374 Methods of inactivation of SARS-CoV-2 for downstream biological assays
Patterson, E. I.; Prince, T.; Anderson, E. R.; Casas-Sanchez, A.; Smith, S. L.; Cansado-Utrilla, C.; Turtle, L.; Hughes, G. L.
10.1101/2020.05.21.108035 — microbiology — Posted on 2020-05-23
1375 GraphGR: A graph neural network to predict the effect of pharmacotherapy on the cancer cell growth
Singha, M.; Pu, L.; Shawky, A.-E.-M.; Busch, K.; Wu, H.-C.; Ramanujam, J.; Brylinski, M.
10.1101/2020.05.20.107458 — bioinformatics — Posted on 2020-05-23
1377 High-speed adaptive optics line-scan OCT for cellular-resolution optoretinography
Pandiyan, V. P.; Jiang, X.; Bertelli, A. M.; Kuchenbecker, J. A.; Sharma, U.; Sabesan, R.
10.1101/2020.05.20.105478 — bioengineering — Posted on 2020-05-23
1388 Discovery of multiple anti-CRISPRs uncovers anti-defense gene clustering in mobile genetic elements
Pinilla-Redondo, R.; Shehreen, S.; Marino, N. D.; Fagerlund, R. D.; Brown, C. M.; Soerensen, S. J.; Fineran, P. C.; Bondy-Denomy, J.
10.1101/2020.05.22.110304 — microbiology — Posted on 2020-05-23
1390 Dual midbrain and forebrain origins of thalamic inhibitory interneurons
Jager, P.; Moore, G.; Calpin, P.; Durmishi, X.; Kita, Y.; Salgarella, I.; Wang, Y.; Schultz, S. R.; Brickley, S. G.; Shimogori, T.; Delogu, A.
10.1101/651745 — developmental biology — Posted on 2020-05-23
1392 Multivalent proteins rapidly and reversibly phase-separate upon osmotic cell volume change
Jalihal, A. P.; Pitchiaya, S.; Xiao, L.; Bawa, P.; Jiang, X.; Bedi, K.; Parolia, A.; Cieslik, M.; Ljungman, M.; Chinnaiyan, A. M.; Walter, N. G.
10.1101/748293 — cell biology — Posted on 2020-05-23
1394 An RNA dynamic ensemble at atomic resolution
Shi, H.; Rangadurai, A.; Abou Assi, H.; Roy, R.; Case, D. A.; Herschlag, D.; Yesselman, J. D.; Al-Hashimi, H. M.
10.1101/2020.05.13.092981 — biophysics — Posted on 2020-05-23
1395 Benchmarking atlas-level data integration in single-cell genomics
Luecken, M. D.; Buttner, M.; Chaichoompu, K.; Danese, A.; Interlandi, M.; Mueller, M. F.; Strobl, D. C.; Zappia, L.; Dugas, M.; Colome-Tatche, M.; Theis, F. J.
10.1101/2020.05.22.111161 — bioinformatics — Posted on 2020-05-23
1398 Mountain stoneflies may tolerate warming streams: evidence from organismal physiology and gene expression
Hotaling, S.; Shah, A. A.; McGowan, K. L.; Tronstad, L. M.; Giersch, J. J.; Finn, D. S.; Woods, H. A.; Dillon, M. E.; Kelley, J. L.
10.1101/2019.12.16.878926 — physiology — Posted on 2020-05-23
1399 Whole genome analysis of four Bangladeshi individuals
Khan, S.; Akter, S.; Goswami, B.; Habib, A.; Banu, T. A.; Barton, C.; Osman, E.; Samir, S.; Arjuman, F.; Hasan, S.; Hossain, M. M.
10.1101/2020.05.21.109058 — genomics — Posted on 2020-05-23
1400 Actin binding domain of Rng2 sparsely bound on F-actin strongly inhibits actin movement on myosin II
Hayakawa, Y.; Takaine, M.; Imai, T.; Yamada, M.; Hirose, K.; Ngo, K. X.; Kodera, N.; Tokuraku, K.; Numata, O.; Nakano, K.; Uyeda, T.
10.1101/2020.04.14.041046 — biophysics — Posted on 2020-05-23
1402 Hard to catch: Experimental evidence supports evasive mimicry
Paez, E.; Valkonen, J. K.; Willmott, K. R.; Matos-Maravi, P.; Elias, M.; Mappes, J.
10.1101/2020.05.20.102525 — evolutionary biology — Posted on 2020-05-23
1403 Compromised nuclear envelope integrity drives tumor cell invasion
Nader, G.; Aguera-Gonzalez, S.; Routet, F.; Gratia, M.; Maurin, M.; Cancila, V.; Cadart, C.; Gentili, M.; Yamada, A.; Lodillinsky, C.; Lagoutte, E.; Villard, C.; Viovy, J.-L.; Tripodo, C.; Scita, G.; Manel, N.; Chavrier, P.; Piel, M.
10.1101/2020.05.22.110122 — cell biology — Posted on 2020-05-23
1405 Towards complete and error-free genome assemblies of all vertebrate species
Rhie, A.; McCarthy, S. A.; Fedrigo, O.; Damas, J.; Formenti, G.; Koren, S.; Uliano-Silva, M.; Chow, W.; Fungtammasan, A.; Gedman, G. L.; Cantin, L. J.; Thibaud-Nissen, F.; Haggerty, L.; Lee, C.; Ko, B. J.; Kim, J.; Bista, I.; Smith, M.; Haase, B.; Mountcastle, J.; Winkler, S.; Paez, S.; Howard, J.; Vernes, S. C.; Lama, T. M.; Grutzner, F. C.; Warren, W. C.; Balakrishnan, C.; Burt, D.; George, J. M.; Biegler, M.; Iorns, D.; Digby, A.; Eason, D.; Edwards, T.; Wilkinson, M.; Turner, G. F.; Meyer, A.; Kautt, A. F.; Franchini, P.; Detrich, H. W.; Svardal, H.; Wagner, M.; Naylor, G. J. P.; Pippel, M
10.1101/2020.05.22.110833 — genomics — Posted on 2020-05-23
1407 Physical constrains and functional plasticity of cellulases: Linear scaling relationships for a heterogeneous enzyme reaction
Kari, J.; Molina, G.; Schaller, K.; Christensen, S.; Schiano-di-Cola, C.; Badino, S.; Soerensen, T.; Roejel, N.; Keller, M.; Kolaczkowski, B.; Olsen, J. P.; Krogh, K.; Jensen, K.; Cavaleiro, A. M.; Peters, G. H.; Spodsberg, N.; Borch, K.; Westh, P.
10.1101/2020.05.20.105569 — biochemistry — Posted on 2020-05-23
1408 Characterization of extracellular vesicles produced by Aspergillus fumigatus protoplasts
Rizzo, J.; Chaze, T.; Miranda, K.; Robersen, R. W.; Gorgette, O.; Nimrichter, L.; Matondo, M.; Latge, J.-P.; Beauvais, A.; Rodrigues, M. L.
10.1101/2020.05.21.109926 — microbiology — Posted on 2020-05-23
1415 Evidence for dosage compensation in Coccinia grandis, a plant with a highly heteromorphic XY system
Fruchard, C.; Badouin, H.; Latrasse, D.; Devani, R. S.; Muyle, A.; Rhone, B.; Renner, S. S.; Banerjee, A. K.; Bendahmane, A.; Marais, G. A.
10.1101/2020.05.22.111070 — plant biology — Posted on 2020-05-23
1418 Recruitment of Archaeal DTD is a Key Event in the Emergence of Land Plants
Mazeed, M.; Singh, R.; Kumar, P.; Raman, B.; Kruparani, S. P.; Sankaranarayanan, R.
10.1101/2020.05.22.109876 — biochemistry — Posted on 2020-05-23
1422 Maturation of Purkinje cell firing properties relies on granule cell neurogenesis
van der Heijden, M. E.; Lackey, E. P.; Isleyen, F. S.; Brown, A. M.; Perez, R.; Lin, T.; Zoghbi, H. Y.; Sillitoe, R. V.
10.1101/2020.05.20.106732 — neuroscience — Posted on 2020-05-23
1425 Focal cortical surface cooling is a novel and safe method for intraoperative functional brain mapping
Ibayashi, K.; Cardenas, A. R.; Oya, H.; Kawasaki, H.; Kovach, C. K.; Howard, M. A.; Long, M. A.; Greenlee, J. D. W.
10.1101/2020.05.20.104364 — neuroscience — Posted on 2020-05-23
1426 The hippocampus as the switchboard between perception and memory
Treder, M.; Charest, I.; Michelmann, S.; Martin-Buro, M. C.; Roux, F.; Carceller-Benito, F.; Ugalde-Canitrot, A.; Rollings, D.; Sawlani, V.; Chelvarajah, R.; Wimber, M.; Hanslmayr, S.; Staresina, B. P.
10.1101/2020.05.20.104539 — neuroscience — Posted on 2020-05-23
1428 Seasonal variation in brain mu-opioid receptor availability
Sun, L.; Tang, J.; Liljenback, H.; Honkaniemi, A.; Virta, J.; Isojarvi, J.; Karjalainen, T.; Kantonen, T.; Nuutila, P.; Hietala, J.; Kaasinen, V.; Kalliokoski, K.; Hirvonen, J.; Scheinin, H.; Helin, S.; Eerola, K.; Savontaus, E.; Yatkin, E.; Rinne, J. O.; Roivainen, A.; Nummenmaa, L.
10.1101/2020.05.20.104349 — neuroscience — Posted on 2020-05-23
1429 Bacillus anthracis chain length, a virulence determinant, is regulated by a transmembrane Ser/Thr protein kinase PrkC
Gupta, M.; Singh, Y.; Dhasmana, N.; Kumar, N.; Gangwal, A.; keshavam, C. c.; Singh, L. K.; Sangwan, N.; nashier, P.; biswas, S.; Pomerantsev, A. P.; Leppla, S. H.
10.1101/2020.03.15.992834 — microbiology — Posted on 2020-05-23
1430 High-resolution population-specific recombination rates and their effect on phasing and genotype imputation
Hassan, S.; Surakka, I.; Taskinen, M.-R.; Salomaa, V.; Palotie, A.; Wessman, M.; Tukiainen, T.; Pirinen, M.; Palta, P.; Ripatti, S.
10.1101/2020.05.20.106831 — genomics — Posted on 2020-05-23
1435 Proper names from story recall are associated with beta-amyloid in cognitively unimpaired adults at risk for Alzheimer's disease
Mueller, K. D.; Koscik, R.; Du, L.; Bruno, D.; Jonaitis, E. M.; Koscik, A. Z.; Christian, B.; Betthauser, T. J.; Chin, N.; Hermann, B. P.; Johnson, S. C.
10.1101/2020.05.22.106195 — neuroscience — Posted on 2020-05-23
1437 Dopamine responses reveal efficient coding of cognitive variables
Motiwala, A.; Soares, S.; Atallah, B. V.; Paton, J. J.; Machens, C. K.
10.1101/2020.05.20.100065 — neuroscience — Posted on 2020-05-23
1438 Ultra-high field (10.5 T) resting state fMRI in the macaque
Yacoub, E.; Grier, M. D.; Auerbach, E. J.; Lagore, R. L.; Harel, N.; Ugurbil, K.; Adriany, G.; Zilverstand, A.; Hayden, B. Y.; Heilbronner, S. R.; Zimmermann, J.
10.1101/2020.05.21.109595 — neuroscience — Posted on 2020-05-23
1439 Stable unmethylated DNA demarcates expressed genes and their cis-regulatory space in plant genomes
Crisp, P. A.; Marand, A. A.; Noshay, J. M.; Zhou, P.; Lu, Z.; Schmitz, R. J.; Springer, N. M.
10.1101/2020.05.21.109744 — genomics — Posted on 2020-05-23
1440 Detection of a multi-disease biomarker in Salivawith Graphene Field Effect Transistors
Kumar, N.; Gray, M.; Ortiz-Marquez, J. C.; Weber, A.; Desmond, C. R.; Argun, A.; van Opijnen, T.; Burch, K. S.
10.1101/2020.05.22.111047 — biophysics — Posted on 2020-05-23
1441 The interaction of DNA repair factors ASCC2 and ASCC3 is affected by somatic cancer mutations
Jia, J.; Absmeier, E.; Holton, N.; Pietrzyk-Brzezinska, A. J.; Hackert, P.; Bohnsack, K. E.; Bohnsack, M. T.; Wahl, M. C.
10.1101/2020.05.22.111591 — biochemistry — Posted on 2020-05-23
1443 Examining interspecific density-dependent dispersal in forest small mammals
Denomme-Brown, S. T.; Cottenie, K.; Falls, J. B.; Falls, E. A.; Brooks, R. J.; McAdam, A. G.
10.1101/2020.05.21.109827 — ecology — Posted on 2020-05-23
1444 Translocation of an arctic seashore plant reveals signs of maladaptation to altered climatic conditions
Hallfors, M. H.; Lehvavirta, S.; Aandahl, T. R.; Lehtimaki, I.; Nilsson, L.-O.; Ruotsalainen, A.-L.; Schulman, L. E.; Hyvarinen, M. T.
10.1101/2020.05.22.109868 — ecology — Posted on 2020-05-23
1445 Integrated cross-study datasets of genetic dependencies in cancer
Pacini, C.; Dempster, J. M.; Goncalves, E.; Najgebauer, H.; Karakoc, E.; van der Meer, D.; Barthorpe, A.; Lightfoot, H.; Jaaks, P.; McFarldan, J. M.; Garnett, M.; Tsherniak, A.; Iorio, F.
10.1101/2020.05.22.110247 — bioinformatics — Posted on 2020-05-23
1448 The specificity of SRC Homology 3 (SH3) domain interactions is modulated by their protein context in vivo
Dionne, U.; Bourgault, E.; Dube, A. K.; Bradley, D.; Chartier, F.; Dandage, R.; Dibyachintan, S.; Despres, P. C.; Gish, G. D.; Lambert, J.-P.; Bisson, N.; Landry, C. R.
10.1101/2020.05.18.103002 — systems biology — Posted on 2020-05-23
1450 Intrinsic connectivity of the prefrontal cortex and striato-limbic system respectively differentiate Major Depressive from Generalized Anxiety Disorder
Xu, X.; Dai, J.; Chen, Y.; Liu, C.; Xin, F.; Zhou, X.; Zhou, F.; Stamatakis, E.; Yao, S.; Lizhu, L.; Huang, Y.; Wang, J.; Zou, Z.; Vatansever, D.; Kendrick, K. M.; Zhou, B.; Becker, B.
10.1101/2020.05.19.105148 — neuroscience — Posted on 2020-05-23
1451 Intrinsic defects in lymph node stromal cells underpin poor germinal center responses during aging
Denton, A. E.; Silva-Cayetano, A.; Dooley, J.; Hill, D. L.; Carr, E. J.; Robert, P. A.; Meyer-Hermann, M.; Liston, A.; Linterman, M. A.
10.1101/2020.05.07.082255 — immunology — Posted on 2020-05-23
1457 Discriminating changes in protein structure using PTAD conjugation to tyrosine
Moinpour, M.; Barker, N. K.; Guzman, L. E.; Jewett, J. C.; Langlais, P. R.; Schwartz, J. C.
10.1101/2020.02.04.934406 — biochemistry — Posted on 2020-05-23
1458 A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma
Ruffieux, H.; Carayol, J.; Popescu, R.; Harper, M.-E.; Dent, R.; Saris, W.; Astrup, A.; Hager, J.; Davison, A.; Valsesia, A.
10.1101/524405 — genetics — Posted on 2020-05-23
1459 β-catenin perturbations control differentiation programs in mouse embryonic stem cells
Pedone, E.; Failli, M.; Gambardella, G.; De Cegli, R.; di Bernardo, D.; Marucci, L.
10.1101/2020.05.15.098137 — cell biology — Posted on 2020-05-23
1460 Radiosynthesis and Preclinical Evaluation of Ga-NOTA-Folate for PET Imaging of Folate Receptor βPositive Macrophages
Moisio, O.; Palani, S.; Virta, J.; Elo, P.; Liljenback, H.; Tolvanen, T.; Kakela, M.; Miner, M. G.; Atencio Herre, E.; Marjamaki, P.; Ord, T.; Heinaniemi, M.; Kaikkonen-Maatta, M.; Zhang, F.; Srinivasarao, M.; Knuuti, J.; Low, P. S.; Saraste, A.; Li, X.-G.; Roivainen, A.
10.1101/2020.05.18.102483 — biochemistry — Posted on 2020-05-23
1461 Children's Hospital Los Angeles COVID-19 Analysis Research Database (CARD) - A Resource for Rapid SARS-CoV-2 Genome Identification Using Interactive Online Phylogenetic Tools
Shen, L.; Maglinte, D.; Ostrow, D.; Pandey, U.; Bootwalla, M.; Ryutov, A.; Govindarajan, A.; Ruble, D.; Han, J.; Triche, T. J.; Dien Bard, J.; Biegel, J. A.; Judkins, A. R.; Gai, X.
10.1101/2020.05.11.089763 — genomics — Posted on 2020-05-23
1463 Exploiting the GTEx resources to decipher the mechanisms at GWAS loci
Barbeira, A. N.; Bonazzola, R.; Gamazon, E. R.; Liang, Y.; Park, Y.; Kim-Hellmuth, S.; Wang, G.; Jiang, Z.; Zhou, D.; Hormozdiari, F.; Liu, B.; Rao, A.; Hamel, A. R.; Pividori, M. D.; Aguet, F.; GTEx GWAS Working Group, ; Bastarache, L.; Jordan, D. M.; Verbanck, M.; Do, R.; GTEx Consortium, ; Stephens, M.; Ardlie, K.; McCarthy, M.; Montgomery, S. B.; Segre, A.; Brown, C. D.; Lappalainen, T.; Wen, X.; Im, H. K.
10.1101/814350 — genetics — Posted on 2020-05-23
1464 Quantification of the Resilience and Vulnerability of HIV-1 Native GlycanShield at Atomistic Detail
Chakraborty, S.; Berndsen, Z. T.; Hengartner, N. W.; Korber, B. T.; Ward, A. B.; Gnanakaran, S.
10.1101/846071 — biophysics — Posted on 2020-05-23
1466 So you think you can PLS-DA?
Perez, D. R.; Guan, H.; Madhivanan, P.; Mathee, K.; Narasimhan, G.
10.1101/207225 — bioinformatics — Posted on 2020-05-23
1467 Novel insights into the structure and transport mechanisms of TAPT1
Parvez, M. S. A.; Rahman, M. M.; Morshed, M. N.; Rahman, D.; Anwar, S.; Coucke, P.; Hosen, M. J.
10.1101/2020.05.18.099887 — biochemistry — Posted on 2020-05-23
1471 Experimentally revealed stochastic preferences for multi-component choice options
Pastor-Bernier, A.; Volkmann, K.; Stasiak, A.; Grabenhorst, F.; Schultz, W.
10.1101/832881 — neuroscience — Posted on 2020-05-23
1473 Golgi-Dependent Copper Homeostasis Sustains Synaptic Development and Mitochondrial Content
Hartwig, C.; Macias Mendez, G.; Bhattacharjee, S.; Vrailas-Mortimer, A.; Zlatic, S. A.; Freeman, A. A.; Gokhale, A.; Concilli, M.; Sapp Savas, C.; Rudin-Rush, S.; Palmer, L.; Shearing, N.; Margewich, L.; McArthy, J.; Taylor, S.; Roberts, B. R.; Lupashin, V.; Polishchuk, R. R.; Cox, D. N.; Jorquera, R. A.; Faundez, V. M.
10.1101/2020.05.22.110627 — neuroscience — Posted on 2020-05-23
1474 Analysis of brain atrophy and local gene expression in genetic frontotemporal dementia
Altmann, A.; Cash, D. M.; Bocchetta, M.; Heller, C.; Reynolds, R. H.; Moore, K.; Convery, R. S.; Thomas, D.; van Swieten, J. C.; Moreno, F.; Sanchez-Valle, R.; Borroni, B.; Laforce, R.; Masellis, M.; Tartaglia, C.; Graff, C.; Galimberti, D.; Rowe, J.; Finger, E.; Synofzik, M.; Vandenberghe, R.; de Mendonca, A.; Tagliavini, F.; Santana, I.; Ducharme, S.; Butler, C.; Gerhard, A.; Levin, J.; Danek, A.; Frisoni, G.; Ghidoni, R.; Sorbi, S.; Otto, M.; Ryten, M.; Rohrer, J. D.; Genetic FTD Initiative, GENFI,
10.1101/2019.12.11.872143 — neuroscience — Posted on 2020-05-23
1476 Genetic structure and molecular diversity of Brazilian grapevine germplasm: management and use in breeding programs
de Oliveira, G. L.; de Souza, A. P.; de Oliveira, F. A.; Zucchi, M. I.; de Souza, L. M.; Moura, M. F.
10.1101/2020.05.05.078865 — molecular biology — Posted on 2020-05-23
1478 Disease-relevant single cell photonic signatures identify S100β stem cells and their myogenic progeny in vascular lesions
Molony, C.; King, D.; di Luca, M.; Olayinka, A.; Hakimjavadi, R.; Julius, L. A.; Fitzpatrick, E.; Burtenshaw, D.; Healy, K.; Finlay, E.; Kernan, D.; Llobera, A.; Liu, W.; Morrow, D.; Redmond, E. M.; Ducree, J.; Cahill, P. A.
10.1101/2020.05.13.093518 — cell biology — Posted on 2020-05-23
1481 Exifone is a Potent HDAC1 Activator with Neuroprotective Activity in Human Neuronal Models of Neurodegeneration
Patnaik, D.; Pao, P.-C.; Zhao, W.-N.; Silva, M. C.; Hylton, N. K.; Chindavong, P. S.; Pan, L.; Tsai, L.-H.; Haggarty, S. J.
10.1101/2020.03.02.973636 — biochemistry — Posted on 2020-05-23
1483 A clinically validated human capillary blood transcriptome test for global systems biology studies
Toma, R.; Pelle, B.; Duval, N.; Parks, M. M.; Gopu, V.; Tily, H.; Hatch, A.; Perlina, A.; Banavar, G. S.; Vuyisich, M.
10.1101/2020.05.22.110080 — systems biology — Posted on 2020-05-23
1485 Association between erythrocyte dynamics and vessel remodelling in developmental vascular networks
Zhou, Q.; Perovic, T.; Fechner, I.; Edgar, L. T.; Hoskins, P. R.; Gerhardt, H.; Krüger, T.; Bernabeu, M. O.
10.1101/2020.05.21.106914 — developmental biology — Posted on 2020-05-23
1486 Cellular transformation by combined lineage conversion and oncogene expression
Sahu, B.; Pihlajamaa, P.; Zhang, K.; Palin, K.; Ahonen, S.; Cervera, A.; Ristimaki, A.; Aaltonen, L.; Hautaniemi, S.; Taipale, J.
10.1101/525600 — cancer biology — Posted on 2020-05-23
1487 Reconstruction of Fur pan-regulon uncovers the complexity and diversity of transcriptional regulation in E. coli
Gao, Y.; Bang, I.; Seif, Y.; Nam, G.; Sastry, A. V.; Chen, K.; Monk, J.; Choudhary, K. S.; Seo, S. W.; Lee, E.-Y.; Kim, D.; Palsson, B.
10.1101/2020.05.21.109694 — systems biology — Posted on 2020-05-22
1488 Transcriptome and epigenome diversity and plasticity of muscle stem cells following transplantation
Evano, B.; Gill, D.; Hernando-Herraez, I.; Comai, G.; Stubbs, T.; Commere, P.-H.; Reik, W.; Tajbakhsh, S.
10.1101/2020.05.20.107219 — molecular biology — Posted on 2020-05-22
1489 A systematic investigation of human DNA preservation in medieval skeletons
Parker, C. E.; Rohrlach, A. B.; Friederich, S.; Nagel, S.; Meyer, M.; Krause, J.; Bos, K. I.; Haak, W.
10.1101/2020.05.20.106971 — molecular biology — Posted on 2020-05-22
1491 Chromosome-scale genome assembly of Fusarium oxysporum strain Fo47, a fungal endophyte and biocontrol agent
Wang, B.; Yu, H.; Jia, Y.; Dong, Q.; Steinberg, C.; Alabouvette, C.; Edel-Hermann, V.; Kistler, H. C.; Ye, K.; Ma, L.-J.; Guo, L.
10.1101/2020.05.22.110718 — genomics — Posted on 2020-05-23
1495 Genomic Epidemiology of Escherichia coli Isolates from a Tertiary Referral Center in Lilongwe, Malawi
Tegha, G.; Ciccone, E.; Krysiak, R.; Kaphatika, J.; Chikaonda, T.; Ndhlovu, I.; van Duin, D.; Hoffman, I.; Juliano, J. J.; Wang, J. J.
10.1101/2020.05.22.106062 — genetics — Posted on 2020-05-22
1500 Mycobacterium tuberculosis micro-diversity promotes intra-macrophagic persistence and antibiotic tolerance
Genestet, C.; Hodille, E.; Barbry, A.; Berland, J.-L.; Hoffmann, J.; Westeel, E.; Claude, J.-B.; Berti, V.; Bastian, F.; Guichardant, M.; Venner, S.; Ader, F.; Lina, G.; Ginevra, C.; Goutelle, S.; Dumitrescu, O.; on behalf of the Lyon TB study group,
10.1101/2020.05.22.110775 — microbiology — Posted on 2020-05-22
1501 SARS-CoV-2 mutations and where to find them: An in silico perspective of structural changes and antigenicity of the Spike protein
Lemes Goncalves, R.; Leite, T. C. R.; Dias, B. d. P.; Caetano, C. C. d. S.; Souza, A. C. G. d.; Batista, U. d. S.; Barbosa, C. C.; Reyes-Sandoval, A.; Leomil Coelho, L. F.; Silva, B. d. M.
10.1101/2020.05.21.108563 — bioinformatics — Posted on 2020-05-22
1508 Broad-spectrum virucidal activity of bacterial secreted lipases against flaviviruses, SARS-CoV-2 and other enveloped viruses
Yu, X.; Zhang, L.; Tong, L.; Zhang, N.; Wang, H.; Yang, Y.; Shi, M.; Xiao, X.; Zhu, Y.; Wang, P.; Ding, Q.; Zhang, L.; Qin, C.; Cheng, G.
10.1101/2020.05.22.109900 — microbiology — Posted on 2020-05-22
1510 Electric-field-driven microfluidics for rapid CRISPR-based diagnostics and its application to detection of SARS-CoV-2
Ramachandran, A.; Huyke, D. A.; Sharma, E.; Sahoo, M. K.; Banaei, N.; Pinsky, B. A.; Santiago, J. G.
10.1101/2020.05.21.109637 — bioengineering — Posted on 2020-05-22
1511 PD-L1 expression in equine malignant melanoma and functional effects of PD-L1 blockade
Ganbaatar, O.; Konnai, S.; Okagawa, T.; Nojima, Y.; Maekawa, N.; Minato, E.; Kobayashi, A.; Ando, R.; Sasaki, N.; Miyakosi, D.; Ichi, O.; Kato, Y.; Suzuki, Y.; Murata, S.; Ohashi, K.
10.1101/2020.05.22.110395 — immunology — Posted on 2020-05-22
1513 A modular framework for the development of targeted Covid-19 blood transcript profiling panels
Rinchai, D.; Kabeer, B.; Toufiq, M.; Calderone, Z.; Deola, S.; Brummaier, T.; Garand, M.; Branco, R.; Baldwin, N.; Alfaki, M.; Altman, M.; Ballestrero, A.; Bassetti, M.; Zoppoli, G.; De Maria, A.; Tang, B.; Bedognetti, D.; Chaussabel, D.
10.1101/2020.05.20.107243 — immunology — Posted on 2020-05-22
1516 Genome and transcriptome analysis of the mealybug Maconellicoccus hirsutus: A model for genomic Imprinting
Kohli, S.; Gulati, P.; Maini, J.; KV, S.; Pandey, R.; Scaria, V.; Sivasubbu, S.; Narang, A.; Brahmachari, V.
10.1101/2020.05.22.110437 — genomics — Posted on 2020-05-22
1518 A high-throughput neutralizing antibody assay for COVID-19 diagnosis and vaccine evaluation
Muruato, A. E.; Fontes-Garfias, C. R.; Ren, P.; Garcia-Blanco, M. A.; Menachery, V. D.; Xie, X. D.; Shi, P.-Y.
10.1101/2020.05.21.109546 — microbiology — Posted on 2020-05-22
1519 Potently neutralizing human antibodies that block SARS-CoV-2 receptor binding and protect animals
Zost, S. J.; Gilchuk, P.; Case, J. B.; Binshtein, E.; Chen, R. E.; Reidy, J. X.; Trivette, A.; Nargi, R. S.; Sutton, R. E.; Suryadevara, N.; Williamson, L. E.; Chen, E. C.; Jones, T.; Day, S.; Myers, L.; Hassan, A. O.; Kafai, N. M.; Winkler, E. S.; Fox, J. M.; Steinhardt, J. J.; Ren, K.; Loo, Y.-M.; Kallewaard, N. L.; Martinez, D. R.; Schafer, A.; Gralinski, L. E.; Baric, R. S.; Thackray, L. B.; Diamond, M. S.; Carnahan, R. H.; Crowe, J. E.
10.1101/2020.05.22.111005 — immunology — Posted on 2020-05-22
1520 Repeat length increases disease penetrance and severity in C9orf72 ALS/FTD BAC transgenic mice
Pattamatta, A.; Nguyen, L. T. T.; Olafson, H.; Scotti, M. M.; Laboissonniere, L. A.; Richardson, J.; Berglund, A.; Zu, T.; Wang, E. T.-S.; Ranum, L. P. W.
10.1101/2020.05.21.107425 — neuroscience — Posted on 2020-05-22
1522 Discovery of multiple anti-CRISPRs uncovers anti-defense gene clustering in mobile genetic elements
Pinilla-Redondo, R.; Shehreen, S.; Marino, N. D.; Fagerlund, R. D.; Brown, C. M.; Soerensen, S. J.; Fineran, P. C.; Bondy-Denomy, J.
10.1101/2020.05.22.110304 — microbiology — Posted on 2020-05-22
1524 Alternative splicing redefines landscape of commonly mutated genes in acute myeloid leukemia
Rivera, O. D.; Mallory, M. J.; Quesnel-Vallieres, M.; Schultz, D. C.; Carroll, M.; Barash, Y.; Cherry, S.; Lynch, K. W.
10.1101/2020.05.21.107557 — genomics — Posted on 2020-05-22
1526 Effect of nanocarbon molecules on the Arabidopsis thaliana transcriptome
Nakamichi, N.; Sato, A.; Aihara, Y.; Kinoshita, T.; Segawa, Y.; Itami, K.
10.1101/2020.05.22.110171 — plant biology — Posted on 2020-05-22
1528 Massively multiplex single-molecule oligonucleosome footprinting
Abdulhay, N. J.; McNally, C. P.; Hsieh, L. J.; Kasinathan, S.; Keith, A.; Estes, L. S.; Karimzadeh, M.; Underwood, J. G.; Goodarzi, H.; Narlikar, G. J.; Ramani, V.
10.1101/2020.05.20.105379 — genomics — Posted on 2020-05-22
1531 Assessing the co-variability of DNA methylation across peripheral cells and tissues: implications for the interpretation of findings in epigenetic epidemiology
Hannon, E.; Mansell, G.; Burrage, J.; Kepa, A.; Best-Lane, J.; Rose, A.; Heck, S.; Moffitt, T.; Caspi, A.; Arseneault, L.; Mill, J.
10.1101/2020.05.21.107730 — genomics — Posted on 2020-05-22
1535 Substitutional landscape of a split fluorescent protein fragment
Antonescu, O. N.; Rasmussen, A.; Damm, N. A. M.; Heidemann, D. F.; Popov, R.; Nesterov-Mueller, A.; Johansson, K. E.; Winther, J. R.
10.1101/2020.05.20.105668 — synthetic biology — Posted on 2020-05-22
1536 Acetyl-Leucine slows disease progression in lysosomal storage disorders
Kaya, E.; Smith, D.; Smith, C.; Morris, L.; Bremova-Ertl, T.; Cortina-Borja, M.; Fineran, P.; Morten, K.; Poulton, J.; Boland, B.; Spencer, J.; Strupp, M.; Platt, F. M.
10.1101/2020.05.20.105973 — neuroscience — Posted on 2020-05-22
1538 Dopamine signaling in wake promoting clock neurons is not required for the normal regulation of sleep in Drosophila
Fernandez-Chiappe, F.; Hermann-Luibl, C.; Peteranderl, A.; Reinhard, N.; Hieke, M.; Selcho, M.; Shafer, O. T.; Muraro, N. I.; Helfrich-Foerster, C.
10.1101/2020.05.20.106369 — neuroscience — Posted on 2020-05-22
1539 Complement C3-dependent glutamatergic synapse elimination in the developing hippocampus is region- and synapse-specific
Salter, E. W.; Lei, G.; Choi, S.-L.; Ralph, L. T.; Zhang, L.; Jin, F.; Kadia, A.; Wang, J.; Georgiou, J.; Collingridge, G. L.
10.1101/2020.05.20.106930 — neuroscience — Posted on 2020-05-22
1540 Human SKI is a telomere-associated complex involved in DNA-RNA hybrid control and telomere stability.
Herrera-Moyano, E.; Porreca, R. M.; Ranjha, L.; Gonzalez Franco, R.; Skourti, E.; Sun, Y.; Stylianakis, M.; Montoya, A.; Kramer, H.; Vannier, J.-B.
10.1101/2020.05.20.107144 — molecular biology — Posted on 2020-05-22
1541 Perforin-2 limits pathogen proliferation at the maternal-fetal interface
Gayle, P.; McGaughey, V.; Hernandez, R.; Nguyen, K. L.; Arons, M.; Padula, L.; Strbo, N.; Wylie, M.; Colletti, R. C.; Schesser, K.
10.1101/2020.05.20.107193 — immunology — Posted on 2020-05-22
1542 High-resolution population-specific recombination rates and their effect on phasing and genotype imputation
Hassan, S.; Surakka, I.; Taskinen, M. R.; Salomaa, V.; Palotie, A.; Wessman, M.; Tukiainen, T.; Pirinen, M.; Palta, P.; Ripatti, S.
10.1101/2020.05.20.106831 — genomics — Posted on 2020-05-22
1543 Population-scale single-cell RNA-seq profiling across dopaminergic neuron differentiation
Jerber, J.; Seaton, D. D.; Cuomo, A. S.; Kumasaka, N.; Haldane, J.; Steer, J.; Patel, M.; Pearce, D.; Andersson, M.; Bonder, M. J.; Mountjoy, E.; Ghoussaini, M.; Lancaster, M. A.; HipSci Consortium, ; Marioni, J. C.; Merkle, F. T.; Stegle, O.; Gaffney, D. J.
10.1101/2020.05.21.103820 — genetics — Posted on 2020-05-22
1544 Body size and tree species composition determine variation in prey consumption in a forest-inhabiting generalist predator
van Schrojenstein Lantman, I. M.; Vesterinen, E. J.; Hertzog, L. R.; Martel, A.; Verheyen, K.; Lens, L.; Bonte, D.
10.1101/2020.05.20.105866 — ecology — Posted on 2020-05-22
1545 FGFR2 fusion protein-driven mouse models of intrahepatic cholangiocarcinoma unveil a necessary role for Erk signalling
Cristinziano, G.; Porru, M.; Lamberti, D.; Buglioni, S.; Rollo, F.; Amoreo, C. A.; Manni, I.; Giannarelli, D.; Cristofoletti, C.; Russo, G.; Borad, M. J.; Grazi, G. L.; Diodoro, M. G.; Giordano, S.; Forcato, M.; Anastasi, S.; Leonetti, C.; Segatto, O.
10.1101/2020.05.20.106104 — cancer biology — Posted on 2020-05-22
1554 Oxytocinergic modulation of threat-specific amygdala sensitization in humans is critically mediated by serotonergic mechanisms
Liu, C.; Lan, C.; Li, K.; Zhou, F.; Yao, S.; Xu, L.; Yang, N.; Yang, J.; Yong, X.; Ma, Y.; Scheele, D.; Kendrick, K. M.; Becker, B.
10.1101/2020.05.20.105684 — neuroscience — Posted on 2020-05-22
1556 Transcriptional Profiling Reveals the Transcription Factor Networks Regulating the Survival of Striatal Neurons
Yang, L.; Su, Z.; Song, X.; Li, Z.; Wang, Z.; Chen, H.; Shang, Z.; Du, H.; Wen, Y.; Liu, G.; Qi, D.; Li, X.; You, Y.; Xu, Z.; Zhang, Z.
10.1101/2020.05.20.105585 — neuroscience — Posted on 2020-05-22
1557 Biosynthesis and heterologous expression of cacaoidin, the first member of the lanthidin family of RiPPS
Roman-Hurtado, F.; Sanchez-Hidalgo, M.; Martin-Serrano, J. M.; Ortiz-Lopez, F. J.; Genilloud, O.
10.1101/2020.05.20.105809 — molecular biology — Posted on 2020-05-22
1558 Prediction of regional wildfire activity with a probabilistic Bayesian framework
Pimont, F.; Fargeon, H.; Opitz, T.; Ruffault, J.; Barbero, R.; Martin-StPaul, N.; Rigolot, E.; Riviere, M.; Dupuy, J.-L.
10.1101/2020.05.20.105767 — bioengineering — Posted on 2020-05-22
1559 Evaluation and Optimization of Motion Correction in Spinal Cord fMRI Preprocessing
Dehghani, H.; Weber, K. A.; Batouli, S. A. H.; Oghabian, M. A.; Khatibi, A.
10.1101/2020.05.20.103986 — neuroscience — Posted on 2020-05-22
1561 Seasonal variation in brain mu-opioid receptor availability
Sun, L.; Tang, J.; Liljenback, H.; Honkaniem, A.; Virta, J.; Isojarvi, J.; Karjalainen, T.; Kantonen, T.; Nuutila, P.; Hietala, J.; Kaasinen, V.; Kalliokoski, K.; Hirvonen, J.; Scheinin, H.; Helin, S.; Eerola, K.; Savontaus, E.; Yatkin, E.; Rinne, J. O.; Roivainen, A.; Nummenmaa, L.
10.1101/2020.05.20.104349 — neuroscience — Posted on 2020-05-22
1562 Real-time detection of bursts in neuronal cultures using a Neuromorphic Auditory Sensor and Spiking Neural Networks
Dominguez-Morales, J. P.; Buccelli, S.; Gutierrez-Galan, D.; Colombi, I.; Jimenez-Fernandez, A.; Chiappalone, M.
10.1101/2020.05.20.105593 — neuroscience — Posted on 2020-05-22
1563 Single-particle cryo-EM at atomic resolution
Nakane, T.; Kotecha, A.; Sente, A.; McMullan, G.; Masiulis, S.; Brown, P. M. G. E.; Grigoras, I. T.; Malinauskaite, L.; Malinauskas, T.; Miehling, J.; Yu, L.; Karia, D.; Pechnikova, E. V.; de Jong, E.; Keizer, J.; Bischoff, M.; McCormack, J.; Tiemeijer, P.; Hardwick, S. W.; Chirgadze, D. Y.; Murshudov, G.; Aricescu, A. R.; Scheres, S.
10.1101/2020.05.22.110189 — biophysics — Posted on 2020-05-22
1566 PDIP38 is a novel adaptor-like modulator of the mitochondrial AAA+ protease CLPXP
Strack, P. R.; Brodie, E. J.; Zhan, H.; Schuenemann, V. J.; Valente, L. J.; Saiyed, T.; Zeth, K.; Truscott, K. N.; Dougan, D. A.
10.1101/2020.05.19.105320 — biochemistry — Posted on 2020-05-22
1567 Central amygdala mineralocorticoid receptors modulate alcohol self-administration.
Makhijani, V. H.; Irukulapati, P. L.; Van Voorhies, K.; Fortino, B.; Besheer, J.
10.1101/2020.05.19.105262 — neuroscience — Posted on 2020-05-22
1573 Cis-regulatory elements within TEs can influence expression of nearby maize genes
Noshay, J.; Marand, A. P.; Anderson, S. N.; Zhou, P.; Mejia Guerra, M. K.; Lu, Z.; O'Connor, C.; Crisp, P. A.; Hirsch, C. N.; Schmitz, R. J.; Springer, N. M.
10.1101/2020.05.20.107169 — plant biology — Posted on 2020-05-22
1575 A new perspective on the evolution of the interaction between the Vg/VGLL1-3 proteins and the TEAD transcription factors
Mesrouze, Y.; Aguilar, G.; Bokhovchuk, F.; Martin, T.; Martin, C.; Villard, F.; Meyerhofer, M.; Zimmermann, C.; Fontana, P.; Wille, R.; Vorherr, T.; Erdmann, D.; Furet, P.; Scheufler, C.; Schmelzle, T.; Affolter, M.; Chene, P.
10.1101/2020.05.21.107789 — biochemistry — Posted on 2020-05-22
1576 Chronic intake of high dietary sucrose induces sexually dimorphic metabolic adaptations in liver and adipose tissue
Stephenson, E. J.; Stayton, A. S.; Sethuraman, A.; Rao, P. K.; Klazer Gomes, C.; Mulcahy, M. C.; McAllan, L.; Puchowicz, M. A.; Pierre, J. F.; Bridges, D.; Han, J. C.
10.1101/2020.05.20.106922 — physiology — Posted on 2020-05-22
1577 Integration of multiple imaging platforms to uncover cardiac defects in adult zebrafish
Bensimon-Brito, A.; Boezio, G. L.; Cardeira-da-Silva, J.; Wietelmann, A.; Helker, C. S. M.; Ramadass, R.; Piesker, J.; Nauerth, A.; Mueller, C.; Stainier, D. Y. R.
10.1101/2020.05.21.108548 — developmental biology — Posted on 2020-05-22
1585 Microbial diversity of the glass sponge Vazella pourtalesii in response to anthropogenic activities
Busch, K.; Beazley, L.; Kenchington, E.; Whoriskey, F.; Slaby, B. M.; Hentschel, U.
10.1101/2020.05.19.102806 — ecology — Posted on 2020-05-22
1586 Identification a novel subset of alveolar type 2 cells expanding following pneumonectomy and enriched in PD-L1
Ahmadvand, N.; Khosravi, F.; Lingampally, A.; Wasnick, R. M.; Vazquez-Armendariz, A. I.; Heiner, M.; Rivetti, S.; Lv, Y.; Wilhelm, J.; Gunther, A.; Herold, S.; Al Alam, D. M.; Chen, C.; Minoo, P.; Zhang, J.; Bellusci, S.
10.1101/2020.05.20.106005 — cell biology — Posted on 2020-05-22
1588 Multi-Scale 3D Cryo-Correlative Microscopy for Vitrified Cells
Wu, G.-H.; Mitchell, P. G.; Galaz-Montoya, J. G.; Hecksel, C. W.; Sontag, E. M.; Gangadharan, V.; Marshman, J.; Mankus, D.; Bisher, M. E.; Lytton-Jean, A. K.; Frydman, J.; Czymmek, K.; Chiu, W.
10.1101/2020.05.21.107771 — cell biology — Posted on 2020-05-22
1589 Oxidative Stress and Neuroinflammation in a Rat Model of Co-Morbid Obesity and Psychogenic Stress
Santiago Santana, J. M.; Vega-Torres, J. D.; Ontiveros-Angel, P.; Bin Lee, J.; Arroyo Torres, Y.; Cruz Gonzalez, A. Y.; Aponte Boria, E.; Zabala Ortiz, D.; Alvarez Carmona, C.; Figueroa, J. D.
10.1101/2020.05.19.104794 — neuroscience — Posted on 2020-05-22
1591 The role of the hypothalamus in cortical arousaland sleep homeostasis
Yamagata, T.; Kahn, M. C.; Sabanovic, M.; Guillaumin, M. C. C.; Vinne, V. v. d.; Huang, Y.-G.; McKillop, L. E.; Jagannath, A.; Peirson, S. N.; Mann, E. O.; Foster, R. G.; Vyazovskiy, V. V.
10.1101/2020.05.19.104521 — neuroscience — Posted on 2020-05-22
1592 Altered Capicua expression drives regional Purkinje neuron vulnerability through ion channel gene dysregulation in Spinocerebellar ataxia type 1
Chopra, R.; Bushart, D.; Cooper, J.; Yellajoshyula, D.; Morrison, L.; Huang, H.; Scoles, D.; Pulst, S. M.; Orr, H.; Shakkottai, V.
10.1101/2020.05.21.104976 — neuroscience — Posted on 2020-05-22
1594 Mutation of NEKL-4/NEK10 and TTLL genes opposes loss of the CCPP-1 deglutamylase and prevents neuronal ciliary degeneration
Power, K. M.; Akella, J. S.; Gu, A.; Walsh, J. D.; Belotti, S.; Morash, M.; Zhang, W.; Ross, N.; Golden, A.; Smith, H. E.; Barr, M. M.; O'Hagan, R.
10.1101/2020.05.21.108449 — genetics — Posted on 2020-05-22
1595 Ligand-directed two-step labeling to quantify neuronal glutamate receptor trafficking
Ojima, K.; Shiraiwa, K.; Doura, T.; Takato, M.; Komatsu, K.; Yuzaki, M.; Hamachi, I.; Kiyonaka, S.
10.1101/2020.05.20.105296 — biochemistry — Posted on 2020-05-22
1597 Co-expression signatures of combinatorial gene regulation
Gomez-Cano, F.; Qian, X.; Shiu, S.-H.; Krishnan, A.; Grotewold, E.
10.1101/2020.05.19.104935 — systems biology — Posted on 2020-05-22
1598 Multimodal and multisensory coding in the Drosophila larval peripheral gustatory center
Maier, L.; Biocanin, M.; Bues, J.; Meyenhofer, F.; Brunet, C.; Kwon, J. Y.; Deplancke, B. G.; Sprecher, S. G.
10.1101/2020.05.21.109959 — neuroscience — Posted on 2020-05-22
1599 Ramping activity in midbrain dopamine neurons signifies the use of a cognitive map
Guru, A.; Seo, C.; Post, R. J.; Kullakanda, D. S.; Schaffer, J. A.; Warden, M. R.
10.1101/2020.05.21.108886 — neuroscience — Posted on 2020-05-22
1600 Intrinsic connectivity of the prefrontal cortex and striato-limbic system respectively differentiate Major Depressive from Generalized Anxiety Disorder
Xu, X.; Dai, J.; Chen, Y.; Liu, C.; Xin, F.; Zhou, X.; Zhou, F.; Stamatakis, E.; Yao, S.; Lizhu, L.; Huang, Y.; Wang, J.; Zou, Z.; Kendrick, K. M.; Zhou, B.; Becker, B.
10.1101/2020.05.19.105148 — neuroscience — Posted on 2020-05-22
1601 Transcriptional and epigenetic characterization of early striosomes identifies Foxf2 and Olig2 as factors required for development of striatal compartmentation and neuronal phenotypic differentiation
Cirnaru, M.-D.; Song, S.; Tshilenge, K.-T.; Corwin, C.; Mleczko, J.; Galicia Aguirre, C.; Benlhabib, H.; Bendl, J.; Fullard, J.; Apontes, P.; Creus Muncunill, J.; Carlsson, P.; Mooney, S. D.; Roussos, P.; Ellerby, L.; Ehrlich, M. E.
10.1101/2020.05.19.105171 — neuroscience — Posted on 2020-05-22
1603 Postzygotic and germinal de novo mutations in ASD: exploring their biological role
Gonzalez, A. A.; Cabanas, M. C.; Amigo, J.; Penas, J. G.; Regueiro, R. M.; Prieto, M. F.; Parellada, M.; Fontenla, C. R.; Alvarez, A. C.
10.1101/2020.05.21.107987 — genomics — Posted on 2020-05-22
1604 Genome analysis of the fatal tapeworm Sparganum proliferum unravels the cryptic lifecycle and mechanisms underlying the aberrant larval proliferation
Kikuchi, T.; Dayi, M.; Hunt, V. L.; Toyoda, A.; Maeda, Y.; Kondo, Y.; Noya, B. A. d.; Noya, O.; Kojima, S.; Kuramochi, T.; Maruyama, H.
10.1101/2020.05.19.105387 — genomics — Posted on 2020-05-22
1605 Purifying selection on noncoding deletions of human regulatory elements detected using their cellular pleiotropy
Radke, D. W.; Sul, J. H.; Balick, D. J.; Akle, S.; Alzheimer's Disease Neuroimaging Initiative, ; Green, R. C.; Sunyaev, S. R.
10.1101/2020.05.19.105205 — evolutionary biology — Posted on 2020-05-22
1607 Chromosome-level reference genome of the European wasp spider Argiope bruennichi: a resource for studies on range expansion and evolutionary adaptation
Sheffer, M. M.; Hoppe, A.; Krehenwinkel, H.; Uhl, G.; Kuss, A. W.; Jensen, L.; Jensen, C.; Gillespie, R. G.; Hoff, K. J.; Prost, S.
10.1101/2020.05.21.103564 — genomics — Posted on 2020-05-22
1610 A Biophysical Model for Plant Cell Plate Development
Jawaid, M. Z.; Drakakaki, G.; Sinclair, R. M.; Cox, D.
10.1101/2020.05.21.109512 — biophysics — Posted on 2020-05-22
1613 Blunted Neural Reward Responsiveness and Recent Suicidal Ideation in Children and Adolescents: Failure to Replicate Across Two Independent Samples
Gallyer, A. J.; Burani, K.; Mulligan, E. M.; Santopetro, N.; Dougherty, S. P.; Jeon, M. E.; Nelson, B. D.; Joiner, T. E.; Hajcak, G.
10.1101/2020.05.19.104208 — neuroscience — Posted on 2020-05-22
1614 A novel therapeutic antibody screening method using bacterial high-content imaging reveals functional antibody binding phenotypes of Escherichia coli ST131
Maes, M.; Dyson, Z. A.; Smith, S. E.; Goulding, D. A.; Ludden, C.; Baker, S.; Kellam, P.; Reece, S. T.; Dougan, G.; Bartholdson Scott, J.
10.1101/2020.05.22.110148 — microbiology — Posted on 2020-05-22
1615 Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus.
Mathieson, I.; Day, F.; Barban, N.; Tropf, F.; Brazel, D.; eQTLGen Consortium, ; BIOS Consortium, ; Vaez, A.; van Zuydam, N.; Bitarello, B.; Snieder, H.; den Hoed, M.; Ong, K.; Mills, M.; Perry, J.; Human Reproductive Behaviour Consortium,
10.1101/2020.05.19.104455 — genetics — Posted on 2020-05-22
1616 High-altitude adaptation in rhesus macaques
Szpiech, Z. A.; Novak, T. E.; Bailey, N. P.; Stevison, L. S.
10.1101/2020.05.19.104380 — evolutionary biology — Posted on 2020-05-22
1617 Household and climate factors influence Aedes aegypti risk in the arid city of Huaquillas, Ecuador
Martin, J. L.; Stewart-Ibarra, A. M.; Ayala, E. B.; Mordecai, E. A.; Sippy, R.; Heras, F.; Blackburn, J. K.; Ryan, S. J.
10.1101/2020.05.19.104372 — ecology — Posted on 2020-05-22
1620 Field evaluation of biocontrol agents against black-foot and Petri diseases of grapevine
Martinez-Diz, M. d. P.; Diaz-Losada, E.; Andres, M.; Bujanda, R.; Maldonado-Gonzalez, M. M.; Ojeda, S.; Yacoub, A.; Rey, P.; Gramaje, D.
10.1101/2020.05.19.101568 — plant biology — Posted on 2020-05-22
1621 To pool or not to pool: Can we ignore cross-trial variability in FMRI?
Chen, G.; Padmala, S.; Chen, Y.; Taylor, P. A.; Cox, R. W.; Pessoa, L.
10.1101/2020.05.19.102111 — neuroscience — Posted on 2020-05-22
1622 The iron-responsive genome of the chiton Acanthopleura granulata
Varney, R. M.; Speiser, D. I.; McDougall, C.; Degnan, B. M.; Kocot, K. M.
10.1101/2020.05.19.102897 — genomics — Posted on 2020-05-22
1623 THE IMPACT OF MISTRANSLATION ON PHENOTYPIC VARIABILITY AND FITNESS
Samhita, L.; Raval, P. K.; Stephenson, G.; Thutupalli, S.; Agashe, D.
10.1101/2020.05.19.104141 — evolutionary biology — Posted on 2020-05-22
1627 Maturation of complex synaptic connections of layer 5 cortical axons in the posterior thalamic nucleus requires SNAP25
Hayashi, S.; Hoerder-Suabedissen, A.; Kiyokage, E.; Maclachlan, C.; Toida, K.; Knott, G. W.; Molnar, Z.
10.1101/2020.05.20.093070 — neuroscience — Posted on 2020-05-22
1628 Travelling spindles create necessary conditions for spike-timing-dependent plasticity in humans
Dickey, C. W.; Sargsyan, A.; Madsen, J. R.; Eskandar, E. N.; Cash, S. S.; Halgren, E.
10.1101/2020.05.21.079152 — neuroscience — Posted on 2020-05-22
1629 Sweet taste of heavy water
Ben Abu, N.; Mason, P. E.; Klein, H.; Dubovski, N.; Ben Shoshan-Galeczki, Y.; Malach, E.; Prazienkova, V.; Maletinska, L.; Tempra, C.; Chamorro, V. C.; Cvacka, J.; Behrens, M.; Niv, M. Y.; Jungwirth, P.
10.1101/2020.05.22.110205 — biochemistry — Posted on 2020-05-22
1633 Structural Features and Oligomeric Nature of Human Podocin Domain
Mulukala Narasimha, S. K. K.; Irukuvajjula, S. S.; Kumar, K.; Garai, K.; Venkatesu, P.; Vadrevu, R.; Pasupulati, A. k.
10.1101/2020.05.21.108415 — biophysics — Posted on 2020-05-22
1634 Feeding dihydroquercetin and vitamin E to broiler chickens reared at standard and high ambient temperatures
Pirgozliev, V.; Westbrook, C.; Woods, S.; Mansbridge, S. C.; Rose, P.; Whiting, I.; Yovchev, D.; Atanasov, A.; Kljak, K.; Staykova, G.; Ivanova, S.; KARAGECILI, M. R.; Karadas, F.; Stringhini, J. H.
10.1101/2020.05.19.104398 — physiology — Posted on 2020-05-22
1635 Corticothalamic feedback sculpts visual spatial integration in mouse thalamus
Born, G.; Erisken, S.; Schneider, F. A.; Klein, A.; Mobarhan, M. H.; Lao, C. L.; Spacek, M. A.; Einevoll, G. T.; Busse, L.
10.1101/2020.05.19.104000 — neuroscience — Posted on 2020-05-22
1636 PLCG2 as a Risk Factor for Alzheimer's Disease
Tsai, A. P.; Dong, C.; Preuss, C.; Moutinho, M.; Lin, P. B.-C.; Hajicek, N.; Sondek, J.; Bissel, S. J.; Oblak, A. L.; Carter, G. W.; Liu, Y.; Landreth, G. E.; Lamb, B. T.; Nho, K.
10.1101/2020.05.19.104216 — neuroscience — Posted on 2020-05-22
1638 Disturbance-induced changes in size-structure promote coral biodiversity
Alvarez-Noriega, M.; Madin, J. S.; Baird, A. H.; Dornelas, M.; Connolly, S. R.
10.1101/2020.05.21.094797 — ecology — Posted on 2020-05-22
1639 Membrane bending by protein phase separation
Yuan, F.; Alimohamadi, H.; Bakka, B.; Trementozzi, A. N.; Fawzi, N. L.; Rangamani, P.; Stachowiak, J. C.
10.1101/2020.05.21.109751 — biophysics — Posted on 2020-05-22
1640 BTP-7, a novel peptide for therapeutic targeting of malignant brain tumors
von Spreckelsen, N.; Ghotmi, Y.; Fadzen, C.; Wolfe, J.; Farquhar, C.; Hartrampf, N.; Bergmann, S.; Zdioruk, M.; Wasserburg, J. R.; Murrell, E.; Bononi, F.; Luyt, L.; Lamfers, M.; Ligon, K.; Chiocca, E. A.; Viapiano, M.; Pentelute, B.; Lawler, S.; Cho, C.-F.
10.1101/2020.05.21.106633 — bioengineering — Posted on 2020-05-22
1643 CD4+ T-cell epitope prediction by combined analysis of antigen conformational flexibility and peptide-MHCII binding affinity
Charles, T. P.; Moss, D. L.; Bhat, P.; Moore, P. W.; Nicholas, K. A.; Bhattacharya, A.; Mettu, R. R.; Landry, S. J.
10.1101/2020.05.21.109967 — immunology — Posted on 2020-05-22
1651 Viscoelasticity of single macromolecules using Atomic Force Microscopy
Patil, S. P. V.; Rajput, S. S.; deopa, S.; Yadav, J.; Ahlawat, V.; Talele, S.
10.1101/2020.05.21.107888 — biophysics — Posted on 2020-05-22
1654 A mechanistic model improves off-target predictions and reveals the physical basis of SpCas9 fidelity
Eslami-Mossallam, B.; Klein, M.; Smagt, C. v. d.; Sanden, K. v. d.; Jones, S. K.; Hawkins, J. A.; Finkelstein, I. J.; Depken, M.
10.1101/2020.05.21.108613 — biophysics — Posted on 2020-05-22
1661 Single Molecule Light Field Microscopy
Sims, R. R.; Abdul Rehman, S.; Lenz, M. O.; Clark, A.; Sanders, E. W.; Ponjavic, A.; Muresan, L.; Lee, S. F.; O'Holleran, K.
10.1101/2020.05.20.104802 — biophysics — Posted on 2020-05-22
1662 Redox proteomics of stomatal immunity reveals role of a lipid transfer protein in plant defense
Chen, S.; Balmant, K. M.; Lawrence, S. R.; Duong, B. V.; Zhu, F.; Zhu, N.; Nicklay, J. J.
10.1101/2020.05.21.108704 — plant biology — Posted on 2020-05-22
1664 SugarQuant: a streamlined pipeline for multiplexed quantitative site-specific N-glycoproteomics
Fang, P.; Ji, Y.; Silbern, I.; Doebele, C.; Ninov, M.; Lenz, C.; Oellerich, T.; Pan, K.-T.; Urlaub, H.
10.1101/2020.05.20.105726 — biochemistry — Posted on 2020-05-22
1665 Altered N-glycan composition impacts flagella mediated adhesion in Chlamydomonas reinhardtii
Hippler, M.; Xu, N.; Oltmanns, A.; Zhao, L.; Girot, A.; Karimi, M.; Hoepfner, L.; Kelterborn, S.; Scholz, M.; Beissel, J.; Hegemann, P.; Bäumchen, O.; Liu, L.; Huang, K.
10.1101/2020.05.18.102624 — plant biology — Posted on 2020-05-22
1666 SSRIs modulate asymmetric learning from reward and punishment
Michely, J.; Eldar, E.; Erdman, A.; Martin, I. M.; Dolan, R. J.
10.1101/2020.05.21.108266 — neuroscience — Posted on 2020-05-22
1668 Mechanistic insights into ventricular arrhythmogenesis of hydroxychloroquine and azithromycin for the treatment of COVID-19
Wang, G.; Tian, X.; Lu, C.-J.; Flores, H.; Maj, P.; Zhang, K.; Niu, Y.; Wang, L.; Du, Y.; Ji, X.; Xu, Y.; Trafford, A.; Li, D.; Herring, N.; Paterson, D.; Huang, C.; Zhang, H.; Lei, M.; Hao, G.
10.1101/2020.05.21.108605 — pharmacology and toxicology — Posted on 2020-05-22
1670 Chemogenetic manipulation of microglia inhibits neuroinflammation and neuropathic pain in mice
Yi, M.-H.; Liu, Y. U.; Liu, K.; Chen, T.; Bosco, D. B.; Zheng, J.; Xie, M.; Zhou, L.; Qu, W.; Wu, L.-J.
10.1101/2020.05.21.109538 — neuroscience — Posted on 2020-05-22
1672 Arabidopsis cell wall composition determines disease resistance specificity and fitness
Molina, A.; Miedes, E.; Bacete, L.; Rodriguez, T.; Melida, H.; Denance, N.; Sanchez-Vallet, A.; Riviere, M.-P.; Lopez, G.; Freydier, A.; Barlet, X.; Marco, Y.; Pattathil, S.; Hahn, M. G.; Goffner, D.
10.1101/2020.05.21.105650 — plant biology — Posted on 2020-05-22
1673 Active zone compaction in presynaptic homeostatic potentiation
Mrestani, A.; Kollmannsberger, P.; Pauli, M.; Repp, F.; Kittel, R. J.; Eilers, J.; Doose, S.; Sauer, M.; Siren, A.-L.; Heckmann, M.; Paul, M. M.
10.1101/802843 — neuroscience — Posted on 2020-05-22
1675 Cis acting variation is common, can propagates across multiple regulatory layers, but is often buffered in developmental programs
Floc'hlay, S.; Wong, E.; Zhao, B.; Viales, R. R.; Thomas-Chollier, M.; Thieffry, D.; Garfield, D. A.; Furlong, E. E. M.
10.1101/2020.05.21.107961 — genomics — Posted on 2020-05-22
1677 G-baToN: a versatile reporter system for cancer cell-stromal cell interactions.
Tang, R.; Murray, C. W.; Linde, I.; Kramer, N. J.; Tsai, M. K.; Chen, L.; Cai, H.; Gitler, A. D.; Engleman, E.; Winslow, M. M.
10.1101/2020.02.01.929877 — bioengineering — Posted on 2020-05-22
1678 Neuronal and glial 3D chromatin architecture illustrates cellular etiology of brain disorders
Hu, B.; Won, H.; Mah, W.; Park, R.; Kassim, B.; Spiess, K.; Kozlenkov, A.; Crowley, C. A.; Pochareddy, S.; Li, Y.; Dracheva, S.; Sestan, N.; Akbarian, S.; Geschwind, D.
10.1101/2020.05.14.096917 — neuroscience — Posted on 2020-05-22
1684 Superior Colliculus-Projected GABAergic Retinal Ganglion Cells Mediate Looming-Evoked Flight Response
Luo, X.; Cai, D.; Shen, K.; Deng, Q.; Lei, X.; Jin, S.; Zeng, W.-B.; Li, H.; Xu, F.; Huang, L.; Ren, C.; Luo, M.-H.; Xie, T.; Shen, Y.
10.1101/2020.05.14.090167 — neuroscience — Posted on 2020-05-22
1685 Connectomes across development reveal principles of brain maturation in C. elegans
Witvliet, D.; Mulcahy, B.; Mitchell, J. K.; Meirovitch, Y.; Berger, D. R.; Wu, Y.; Liu, Y.; Koh, W. X.; Parvathala, R.; Holmyard, D.; Schalek, R. L.; Shavit, N.; Chisholm, A. D.; Lichtman, J. W.; Samuel, A. D. T.; Zhen, M.
10.1101/2020.04.30.066209 — neuroscience — Posted on 2020-05-22
1689 Rdh54/Tid1 Inhibits Rad51-Rad54-Mediated D-loop Formation and Limits D-loop Length
Shah, S.; Hartono, S. R.; Piazza, A.; Som, V.; Wright, W.; Chedin, F.; Heyer, W.-D.
10.1101/2020.05.20.106641 — biochemistry — Posted on 2020-05-22
1690 Activity-dependent tuning of intrinsic excitability in mouse and human neurogliaform cells
Chittajallu, R.; Auville, K.; Mahadevan, V.; Lai, M.; Hunt, S.; Calvigioni, D.; Pelkey, K. A.; Zaghloul, K.; McBain, C. J.
10.1101/2020.03.24.004465 — neuroscience — Posted on 2020-05-22
1692 Yeast-Expressed SARS-CoV Recombinant Receptor-Binding Domain (RBD219-N1) Formulated with Alum Induces Protective Immunity and Reduces Immune Enhancement
Chen, W.-H.; Tao, X.; Peng, B.-H.; Agrawal, A.; Algaissi, A.; Pollet, J.; Strych, U.; Bottazzi, M. E.; Hotez, P. J.; Lustigman, S.; Du, L.; Jiang, S.; Tseng, C.-T. K.
10.1101/2020.05.15.098079 — immunology — Posted on 2020-05-22
1694 Reconstruction of natural images from responses of primate retinal ganglion cells
Brackbill, N.; Rhoades, C.; Kling, A.; Shah, N. P.; Sher, A.; Litke, A. M.; Chichilnisky, E. J.
10.1101/2020.05.04.077693 — neuroscience — Posted on 2020-05-22
1695 BrainGNN: Interpretable Brain Graph Neural Network for fMRI Analysis
Li, X.; Duncan, J.; Zhou, Y.; Gao, S.; Dvornek, N.; Zhang, M.; Gu, S.; Scheinost, D.; Staib, L.; Ventola, P.; Duncan, J.
10.1101/2020.05.16.100057 — neuroscience — Posted on 2020-05-22
1696 Bi-allelic MCM10 mutations cause telomere shortening with immune dysfunction and cardiomyopathy
Baxley, R. M.; Leung, W.; Schmit, M. M.; Matson, J. P.; Oram, M. K.; Wang, L.; Taylor, J.; Yin, L.; Hedberg, J.; Rogers, C. B.; Harvey, A. J.; Basu, D.; Taylor, J. C.; Pagnamenta, A. T.; Dreau, H.; Craft, J.; Ormondroyd, E.; Watkins, H.; Hendrickson, E. A.; Mace, E. M.; Orange, J.; Aihara, H.; Stewart, G. S.; Blair, E.; Cook, J. G.; Bielinsky, A.-K.
10.1101/844498 — molecular biology — Posted on 2020-05-22
1699 Convergent Antibody Responses to SARS-CoV-2 Infection in Convalescent Individuals
Robbiani, D. F.; Gaebler, C.; Muecksch, F.; Cetrulo Lorenzi, J.; Wang, Z.; Cho, A.; Agudelo, M.; Barnes, C.; Finkin, S.; Hagglof, T.; Oliveira, T.; Viant, C.; Hurley, A.; Millard, K.; Kost, R.; Cipolla, M.; Gazumyan, A.; Gordon, K.; Bianchini, F.; Chen, S.; Ramos, V.; Patel, R.; Dizon, J.; Shimeliovich, I.; Mendoza, P.; Hartweger, H.; Nogueira, L.; Pack, M.; Horowitz, J.; Schmidt, F.; Weisblum, Y.; Hoffmann, H.-H.; Michailidis, E.; Ashbrook, A.; Waltari, E. F.; Pak, J.; Huey-Tubman, K.; Koranda, N.; Hoffman, P.; West, A.; Rice, C.; Hatziioannou, T.; Bjorkman, P.; Bieniasz, P.; Caskey, M.; Nuss
10.1101/2020.05.13.092619 — immunology — Posted on 2020-05-22
1701 Unveiling Crucivirus Diversity by Mining Metagenomic Data
de la Higuera, I.; Kasun, G. W.; Torrance, E. L.; Pratt, A. A.; Maluenda, A.; Colombet, J.; Bisseux, M.; Ravet, V.; Dayaram, A.; Stainton, D.; Kraberger, S.; Zawar-Reza, P.; Goldstien, S.; Briskie, J. V.; White, R.; Taylor, H.; Gomez, C.; Ainley, D. G.; Harding, J. S.; Fontenele, R. S.; Schreck, J.; Ribeiro, S. G.; Oswald, S. A.; Arnold, J. M.; Enault, F.; Varsani, A.; Stedman, K. M.
10.1101/2020.02.27.967703 — evolutionary biology — Posted on 2020-05-22
1703 Micro RNAs are minor constituents of extracellular vesicles and are hardly delivered to target cells
Albanese, M.; Chen, Y.-F. A.; Huels, C.; Gaertner, K.; Tagawa, T.; Keppler, O. T.; Goebel, C.; Zeidler, R.; Hammerschmidt, W.
10.1101/2020.05.20.106393 — cell biology — Posted on 2020-05-22
1706 A CellAge epigenetic clock for expedited discovery of anti-ageing compounds
Lujan, C.; Tyler, E. J.; Ecker, S.; Webster, A. P.; Stead, E. R.; Martinez Miguel, V. E.; Milligan, D.; Garbe, J. C.; Stampfer, M. R.; Beck, S.; Lowe, R.; Bishop, C.; Bjedov, I.
10.1101/803676 — molecular biology — Posted on 2020-05-22
1707 A process-based metacommunity framework linking local and regional scale community ecology
Thompson, P. L.; Guzman, L. M.; De Meester, L.; Horvath, Z.; Ptacnik, R.; Vanschoenwinkel, B.; Viana, D. S.; Chase, J.
10.1101/832170 — ecology — Posted on 2020-05-22
1711 Extreme storms cause rapid, context-dependent shifts in nearshore subtropical bacterial communities
Ares, A.; Mars Brisbin, M.; Sato, K. N.; Martin, J. P.; Iinuma, Y.; Mitarai, S.
10.1101/801886 — microbiology — Posted on 2020-05-22
1713 Variation in space and time: a long-term examination of density-dependent dispersal in a woodland rodent
Denomme-Brown, S. T.; Cottenie, K.; Falls, J. B.; Falls, E. A.; Brooks, R. J.; McAdam, A. G.
10.1101/536144 — ecology — Posted on 2020-05-22
1715 Atlas of Transcription Factor Binding Sites from ENCODE DNase Hypersensitivity Data Across 27 Tissue Types
Funk, C. C.; Casella, A. M.; Jung, S.; Richards, M. A.; Rodriguez, A.; Shannon, P.; Donovan, R.; Heavner, B.; Chard, K.; Xiao, Y.; Glusman, G.; Erteskin-Taner, N.; Golde, T.; Toga, A.; Hood, L.; Van Horn, J. D.; Kesselman, C.; Foster, I.; Ament, S.; Madduri, R.; Price, N. D.
10.1101/252023 — bioinformatics — Posted on 2020-05-22
1717 A prevalent and culturable microbiota links ecological balance to clinical stability of the human lung after transplantation
Das, S.; Bernasconi, E.; Koutsokera, A.; Wurlod, D.-A.; Tripathi, V.; Bonilla-Rosso, G.; Aubert, J.-D.; Derkenne, M.-F.; Mercier, L.; Pattaroni, C.; Rapin, A.; von Garnier, C.; Marsland, B. J.; Engel, P.; Nicod, L. P.
10.1101/2020.05.21.106211 — microbiology — Posted on 2020-05-21
1721 Massively parallel quantification of CRISPR editing in cells by TRAP-seq enables better design of Cas9, ABE, CBE gRNAs of high efficiency and accuracy
Xiang, X.; Qu, K.; Liang, X.; Pan, X.; Wang, J.; Han, P.; Dong, Z.; Liu, L.; Zhong, J.; Ma, T.; Wang, Y.; Yu, J.; Zhao, X.; Li, S.; Xu, Z.; Wang, J.; Zhang, X.; Jiang, H.; Xu, F.; Zou, L.; Teng, H.; Liu, X.; Xu, X.; Wang, J.; Yang, H.; Bolund, L.; Church, G. M.; Lin, L.; Luo, Y.
10.1101/2020.05.20.103614 — systems biology — Posted on 2020-05-21
1722 Computational image analysis reveals the structural complexity of Toxoplasma gondii tissue cysts
Bauman, N.; Ilic, A.; Lijeskic, O.; Uzelac, A.; Klun, I.; Srbljanovic, J.; Cirkovic, V.; Bobic, B.; Stajner, T.; Djurkovic-Djakovic, O.
10.1101/2020.05.21.108118 — microbiology — Posted on 2020-05-21
1724 IgY antibodies against Ebola virus possess post-exposure protection and excellent thermostability
Yang, L.; Zhang, Y.; Wei, Y.; Li, Y.; Wang, X.; Liu, Y.; Tian, D.; Jia, X.; Gong, R.; Liu, W.
10.1101/2020.05.21.108159 — immunology — Posted on 2020-05-21
1727 Coordinating cell polarization and morphogenesis through mechanical feedback
Banavar, S. P.; Trogdon, M.; Drawert, B.; Yi, T.-M.; Petzold, L. R.; Campas, O.
10.1101/2020.05.21.108076 — biophysics — Posted on 2020-05-21
1728 Modeling and Simulation of a Fully-glycosylated Full-length SARS-CoV-2 Spike Protein in a Viral Membrane
Woo, H.; Park, S.-J.; Choi, Y. K.; Park, T.; Tanveer, M.; Cao, Y.; Kern, N. R.; Lee, J.; Yeom, M. S.; Croll, T.; Seok, C.; Im, W.
10.1101/2020.05.20.103325 — biophysics — Posted on 2020-05-21
1730 A natural single-guide RNA repurposes Cas9 to autoregulate CRISPR-Cas expression
Workman, R. E.; Pammi, T.; Nguyen, B. T. K.; Graeff, L. W.; Smith, E.; Sebald, S. M.; Stoltzfus, M. J.; Modell, J. W.
10.1101/2020.05.21.102756 — microbiology — Posted on 2020-05-21
1735 Mechanistic insights into ventricular arrhythmogenesis of hydroxychloroquine and azithromycin for the treatment of COVID-19
Wang, G.; Tian, X.; Lu, C.-J.; Flores, H.; Maj, P.; Zhang, K.; Niu, Y.; Wang, L.; Du, Y.; Ji, X.; Xu, Y.; Trafford, A.; Li, D.; Herring, N.; Paterson, D.; Huang, C.; Zhang, H.; Lei, M.; Lei, G.
10.1101/2020.05.21.108605 — pharmacology and toxicology — Posted on 2020-05-21
1736 Full-field optical coherence tomography for the diagnosis of giant cell arteritis
Maldiney, T.; Greigert, H.; Martin, L.; Benoit, E.; Creuzot-Garcher, C.; Gabrielle, P.-H.; Chassot, J.-M.; Boccara, C.; Balvay, D.; Tavitian, B.; Clement, O.; Audia, S.; Bonnotte, B.; Samson, M.
10.1101/2020.05.21.108092 — pathology — Posted on 2020-05-21
1740 Trimeric SARS-CoV-2 Spike interacts with dimeric ACE2 with limited intra-Spike avidity
Lui, I.; Zhou, X. X.; Lim, S. A.; Elledge, S.; Solomon, P.; Rettko, N. J.; Zha, B. S.; Kirkemo, L. L.; Gramespacher, J. A.; Liu, J.; Muecksch, F.; Lorenzi, J. C. C.; Schmidt, F.; Weisblum, Y.; Robbiani, D. F.; Nussenzweig, M. C.; Hatziioannou, T.; Bieniasz, P. D.; Rosenberg, O.; Leung, K. K.; Wells, J. A.
10.1101/2020.05.21.109157 — biochemistry — Posted on 2020-05-21
1741 Immunization with the receptor-binding domain of SARS-CoV-2 elicits antibodies cross-neutralizing SARS-CoV-2 and SARS-CoV without antibody-dependent enhancement
Zang, J.; Gu, C.; Zhou, B.; Zhang, C.; Yang, Y.; Xu, S.; Zhang, X.; Zhou, Y.; Bai, L.; Wu, Y.; Sun, Z.; Zhang, R.; Deng, Q.; Yuan, Z.; Tang, H.; Qu, D.; Lavillette, D.; Xie, Y.; Huang, Z.
10.1101/2020.05.21.107565 — microbiology — Posted on 2020-05-21
1742 Rapid Isothermal Amplification and Portable Detection System for SARS-CoV-2
Ganguli, A.; Mostafa, A.; Berger, J.; Aydin, M.; Sun, F.; Valera, E.; Cunningham, B. T.; King, W. P.; Bashir, R.
10.1101/2020.05.21.108381 — bioengineering — Posted on 2020-05-21
1744 No evidence for increased transmissibility from recurrent mutations in SARS-CoV-2
van Dorp, L.; Richard, D.; Tan, C. C.; Shaw, L. P.; Acman, M.; Balloux, F.
10.1101/2020.05.21.108506 — genomics — Posted on 2020-05-21
1746 Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer's disease
Ping, L.; Kundinger, S. R.; Duong, D. M.; Yin, L.; Gearing, M.; Lah, J. J.; Levey, A. I.; Seyfried, N. T.
10.1101/2020.05.19.105197 — neuroscience — Posted on 2020-05-21
1749 Deterministic scRNA-seq of individual intestinal organoids reveals new subtypes and coexisting distinct stem cell pools
Bues, J.; Biocanin, M.; Pezoldt, J.; Dainese, R.; Chrisnandy, A.; Rezakhani, S.; Saelens, W.; Gupta, R.; Russeil, J.; Saeys, Y.; Amstad, E.; Claassen, M.; Lutolf, M.; Deplancke, B.
10.1101/2020.05.19.103812 — bioengineering — Posted on 2020-05-21
1750 Discordant evolution of organellar genomes in peas (Pisum L.)
Bogdanova, V. S.; Shatskaya, N. V.; Mglinets, A. V.; Kosterin, O. E.; Vasiliev, G. V.
10.1101/2020.05.19.104224 — evolutionary biology — Posted on 2020-05-21
1751 Network reconstruction for trans acting genetic loci using multi-omics data and prior information
Hawe, J. S.; Saha, A.; Waldenberger, M.; Kunze, S.; Wahl, S.; Mueller-Nurasyid, M.; Prokisch, H.; Grallert, H.; Herder, C.; Peters, A.; Strauch, K.; Theis, F. J.; Gieger, C.; Chambers, J.; Battle, A.; Heinig, M.
10.1101/2020.05.19.101592 — bioinformatics — Posted on 2020-05-21
1752 Deep learning the collisional cross sections of the peptide universe from a million training samples
Meier, F.; Koehler, N. D.; Brunner, A.-D.; Wanka, J.-M. H.; Voytik, E.; Strauss, M. T.; Theis, F. J.; Mann, M.
10.1101/2020.05.19.102285 — systems biology — Posted on 2020-05-21
1756 Crystal structures of SARS-CoV-2 ADP-ribose phosphatase (ADRP): from the apo form to ligand complexes
Michalska, K.; Kim, Y.; Jedrzejczak, R.; Maltseva, N. I.; Stols, L.; Endres, M.; Joachimiak, A.
10.1101/2020.05.14.096081 — molecular biology — Posted on 2020-05-21
1757 The protein expression profile of ACE2 in human tissues
Hikmet, F.; Mear, L.; Edvinsson, A.; Micke, P.; Uhlen, M.; Lindskog, C.
10.1101/2020.03.31.016048 — cell biology — Posted on 2020-05-21
1759 The impact of super-spreaders in COVID-19: mapping genome variation worldwide
Gomez-Carballa, A.; Bello, X.; Pardo-Seco, J.; Martinon-Torres, F.; Salas, A.
10.1101/2020.05.19.097410 — genomics — Posted on 2020-05-21
1762 Large scale genomic analysis of 3067 SARS-CoV-2 genomes reveals a clonal geo-distribution and a rich genetic variations of hotspots mutations
Laamarti, M.; Alouane, T.; Kartti, S.; Chemao-Elfihri, M. W.; Hakmi, M.; Essabbar, A.; Laamarti, M.; Hlali, H.; Allam, L.; El Hafidi, N.; El Jaoudi, R.; Allali, I.; Marchoudi, N.; Fekkak, J.; Benrahma, H.; Nejjari, C.; Amzazi, S.; Belyamani, L.; Ibrahimi, A.
10.1101/2020.05.03.074567 — genomics — Posted on 2020-05-21
1766 Poultry farmer response to disease outbreaks in smallholder farming systems
Delabouglise, A.; Thanh, N. T. L.; Xuyen, H. T. A.; Nguyen-Van-Yen, B.; Tuyet, P. N.; Lam, H. M.; Boni, M. F.
10.1101/2020.05.19.104059 — systems biology — Posted on 2020-05-21
1767 Divergent CPEB prion-like domains reveal different assembly mechanisms for a generic amyloid-like fold
Hervas, R.; Fernandez-Ramirez, M. d. C.; Galera-Prat, A.; Suzuki, M.; Nagai, Y.; Bruix, M.; Menendez, M.; Laurents, D. V.; Carrion-Vazquez, M.
10.1101/2020.05.19.103804 — neuroscience — Posted on 2020-05-21
1768 Medial Prefrontal Cortex Interacts with the Anteromedial Thalamus in Motivation and Dopaminergic Activity
Yang, C.; Hu, Y.; Talishinsky, A. D.; Potter, C. T.; Ramsey, L. A.; Kesner, A. J.; Don, R. F.; Junn, S.; Tan, A.; Pierce, A. F.; Nicolas, C.; Calva, C. B.; Su, C.; Mejia-Aponte, C. A.; Wang, D. V.; Lu, H.; Yang, Y.; Ikemoto, S.
10.1101/2020.05.19.104026 — neuroscience — Posted on 2020-05-21
1770 Did I imagine that? The functional role of paracingulate cortex in reality monitoring
Garrison, J. R.; Saviola, F.; Morgenroth, E.; Barker, H.; Luhrs, M.; Simons, J.; Fernyhough, C. P.; Allen, P.
10.1101/2020.05.19.103572 — neuroscience — Posted on 2020-05-21
1771 Acquired fluoroquinolone resistance genes in corneal isolates of Pseudomonas aeruginosa
Khan, M.; Summers, S.; Rice, S. A.; Stapleton, F.; Willcox, M. D. P.; Subedi, D.
10.1101/2020.05.17.100396 — microbiology — Posted on 2020-05-21
1776 Evidence for motility in 3.4 Gyr-old organic-walled microfossils ?
Delarue, F.; Bernard, S.; Sugitani, K.; Robert, F.; Tartese, R.; Albers, S.-V.; Duhamel, R.; Pont, S.; Derenne, S.
10.1101/2020.05.19.103424 — paleontology — Posted on 2020-05-21
1777 Transient resting-state network dynamics in cognitive ageing
Tibon, R.; Tsvetanov, K. A.; Price, D.; Nesbitt, D.; Cam-CAN, ; Henson, R.
10.1101/2020.05.19.103531 — neuroscience — Posted on 2020-05-21
1778 Phytoplankton trigger the production of cryptic metabolites in the marine actinobacteria Salinispora tropica
Chhun, A.; Sousoni, D.; Aguilo-Ferretjans, M. d. M.; Song, L.; Corre, C.; Christie-Oleza, J. A.
10.1101/2020.05.18.103358 — microbiology — Posted on 2020-05-21
1781 Electronic blood vessel
Cheng, S.; Hang, C.; Ding, L.; Jia, L.; Tang, L.; Mou, L.; Qi, J.; Dong, R.; Zheng, W.; Zhang, Y.; Jiang, X.
10.1101/2020.05.19.103457 — bioengineering — Posted on 2020-05-21
1784 Nutrient sensing pathways regulating adult reproductive diapause in C. elegans
Eustice, M.; Reece, J. M.; Konzman, D.; Ghosh, S.; Alston, J.; Hansen, T.; Golden, A.; Hanover, J.
10.1101/2020.05.21.108340 — genetics — Posted on 2020-05-21
1785 ABHD17 enzymes regulate dynamic plasma membrane palmitoylation and N-Ras-dependent cancer growth
Remsberg, J. R.; Suciu, R. M.; Zambetti, N. A.; Hanigan, T. W.; Firestone, A. J.; Inguva, A.; Long, A.; Ngo, N.; Lum, K. M.; Henry, C. L.; Richardson, S. K.; Predovic, M.; Huang, B.; Howell, A. R.; Niphakis, M. J.; Shannon, K.; Cravatt, B. F.
10.1101/2020.05.21.108316 — cancer biology — Posted on 2020-05-21
1788 Non-canonical cell death by reassortant reovirus
Rodriguez Stewart, R. M.; Raghuram, V.; Berry, J. T. L.; Mainou, B. A.
10.1101/2020.05.20.107706 — microbiology — Posted on 2020-05-21
1789 Abl kinase deficiency promotes AKT pathway activation and prostate cancer progression and metastasis
Marchal, M. A.; Moose, D.; Varzavand, A.; Taylor, D.; Brown, J. A.; Henry, M. D.; Stipp, C. S.
10.1101/2020.05.19.104679 — cancer biology — Posted on 2020-05-21
1790 S-nitrosylated and non-nitrosylated COX2 has differential expression and distinct subcellular localization in normal and breast cancer tissue
Jindal, S.; Pennock, N. D.; Klug, A.; Narasimhan, J.; Calhoun, A.; Roberts, M. R.; Tamimi, R. M.; Eliassen, A. H.; Weinmann, S.; Borges, V. F.; Schedin, P. J.
10.1101/2020.05.20.104612 — cancer biology — Posted on 2020-05-21
1792 Capillary Electrophoresis of PCR fragments with labelled primers for testing the SARS-Cov-2
GOMEZ, J.; MELON, S.; BOGA, J. A.; Alvarez-Arguelles, M. E.; ROJO-ALBA, S.; LEAL-NEGREDO, A.; Castello-Abietar, C.; ALVAREZ, V.; CUESTA-LLAVONA, E.; COTO, E.
10.1101/2020.05.16.099242 — microbiology — Posted on 2020-05-21
1794 The SARS-CoV-2 cytopathic effect is blocked with autophagy modulators
Gorshkov, K.; Chen, C. Z.; Bostwick, R.; Rasmussen, L.; Xu, M.; Pradhan, M.; Tran, B. N.; Zhu, W.; Shamim, K.; Huang, W.; Hu, X.; Shen, M.; Klumpp-Thomas, C.; Itkin, Z.; Shinn, P.; Simeonov, A.; Michael, S.; Hall, M. D.; Lo, D. C.; Zheng, W.
10.1101/2020.05.16.091520 — pharmacology and toxicology — Posted on 2020-05-21
1796 Integrative analysis of mutated genes and mutational processes reveals seven colorectal cancer subtypes
Dashti, H.; Dehzangi, A.; Bayati, M.; Breen, J.; Lovell, N.; Ebrahimi, D.; Rabiee, H. R.; Alinejad-Rokny, H.
10.1101/2020.05.18.101022 — cancer biology — Posted on 2020-05-21
1800 Time between milestone events in the Alzheimer's disease amyloid cascade
Insel, P.; Donohue, M.; Berron, D.; Hansson, O.; Mattsson-Carlgren, N.
10.1101/2020.05.18.103226 — neuroscience — Posted on 2020-05-21
1803 HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signaling
Giroud, M.; Tsokanos, F. F.; Caratti, G.; Khani, S.; Vogl, E. S.; Irmler, M.; Glantschnig, C.; Lozano, M. G.; Kotschi, S.; Hass, D.; Khan, A. A.; Garcia, M. R.; Mattijssen, F.; Maida, A.; Tews, D.; Posovszky, P. F.; Feuchtinger, A.; Virtanen, K. A.; Beckers, J.; Wabitsc, M.; Bluher, M.; Tuckermann, J. P.; Scheideler, M.; Bartelt, A.; Herzig, S.
10.1101/2020.05.18.102699 — molecular biology — Posted on 2020-05-21
1807 Ant community potential for pest control in olive groves: management and landscape effects
Martinez-Nunez, C.; Rey, P. J.; Salido, T.; Manzaneda, A. J.; Camacho, F. M.; Isla, J.
10.1101/2020.05.18.103028 — ecology — Posted on 2020-05-21
1811 Mitochondrial Enzymes of the Urea Cycle Cluster at the Inner Mitochondrial Membrane
Haskins, N.; Bhuvanendran, S.; Gams, A.; Kanholm, T.; Kocher, K. M.; LoTempio, J.; Krohmaly, K. I.; Sohai, D.; Stearrett, N.; Bonner, E.; Tuchman, M.; Morizono, H.; Jaiswal, J. K.; Caldovic, L.
10.1101/2020.05.18.102988 — biochemistry — Posted on 2020-05-21
1813 Pathophysiological regulation of lung function by the free fatty acid receptor FFA4
Tobin, A. B.; Prihandoko, R.; Kaur, D.; Wiegman, C. H.; Alvarez-Curto, E.; Donovan, C.; Chachi, L.; Ulven, T.; Tyas, M. R.; Euston, E.; Dong, Z.; Alharbi, A. G.; Kim, R.; Lowe, J. G.; Hansbro, P. M.; Chung, K. F.; Brightling, C. E.; Milligan, G.
10.1101/2020.05.18.101170 — pharmacology and toxicology — Posted on 2020-05-21
1817 The H-NS regulator plays a role in the stress induced by carbapenemase expression in Acinetobacter baumannii
Huang, F.; Fitchett, N.; Razo-Gutierrez, C.; Li, C.; Ra, G.; Lopez, C.; Gonzalez, L. J.; Sieira, R.; Vila, A. J.; Bonomo, R. A.; Ramirez, M. S.
10.1101/2020.05.18.103317 — microbiology — Posted on 2020-05-21
1818 Inversion of pheromone preference optimizes foraging in C. elegans
Dal Bello, M.; Perez-Escudero, A.; Schroeder, F. C.; Gore, J.
10.1101/2020.05.18.101352 — ecology — Posted on 2020-05-21
1819 Tumor stiffening reversion through collagen crosslinking inhibition improves T cell migration and anti-PD-1 treatment
Nicolas-Boluda, A.; Vaquero, J.; Barrin, S.; Kantari-Mimoun, C.; Ponzo, M.; Renault, G.; Deptula, P.; Pogoda, K.; Bucki, R.; Cascone, I.; Courty, J.; Fouassier, L.; Gazeau, F.; Donnadieu, E.
10.1101/2020.05.19.104430 — cancer biology — Posted on 2020-05-21
1820 SPATIAL ORGANIZATION OF TRANSCRIBED EUKARYOTIC GENES
Leidescher, S.; Nuebler, J.; Feodorova, Y.; Hildebrand, E.; Ullrich, S.; Bultmann, S.; Link, S.; Thanisch, K.; Dekker, J.; Leonhardt, H.; Mirny, L.; Solovei, I.
10.1101/2020.05.20.106591 — cell biology — Posted on 2020-05-21
1823 Human es-fMRI Resource: Concurrent deep-brain stimulation and whole-brain functional MRI
Thompson, W. H.; Nair, R.; Oya, H.; Esteban, O.; Shine, J. M.; Petkov, C.; Poldrack, R. A.; Howard, M.; Adolphs, R.
10.1101/2020.05.18.102657 — neuroscience — Posted on 2020-05-21
1826 Metagenomic profiling of ammonia- and methane-oxidizing microorganisms in a Dutch drinking water treatment plant
Poghosyan, L.; Koch, H.; Frank, J.; van Kessel, M. A. H. J.; Cremers, G.; van Alen, T.; Jetten, M. S. M.; Op den Camp, H. J. M.; Luecker, S.
10.1101/2020.05.19.103440 — microbiology — Posted on 2020-05-21
1828 Homeostatic regulation of STING by Golgi-to-ER membrane traffic
Mukai, K.; Ogawa, E.; Uematsu, R.; Kuchitsu, Y.; Uemura, T.; Waguri, S.; Suzuki, T.; Dohmae, N.; Arai, H.; Shum, A. K.; Taguchi, T.
10.1101/2020.05.20.107664 — cell biology — Posted on 2020-05-21
1835 NeuroPycon: An open-source Python toolbox for fast multi-modal and reproducible brain connectivity pipelines
Meunier, D.; Pascarella, A.; Altukhov, D.; Jas, M.; Combrisson, E.; Lajnef, T.; Bertrand-Dubois, D.; Hadid, V.; Alamian, G.; Alves, J.; Barlaam, F.; Saive, A.-L.; Dehgan, A.; Jerbi, K.
10.1101/789842 — neuroscience — Posted on 2020-05-21
1838 Alterations in neuronal physiology, development, and function associated with a common duplication of chromosome 15 involving CHRNA7
Meganathan, K.; Prakasam, R.; Baldridge, D.; Gontarz, P.; Zhang, B.; Urano, F.; Bonni, A.; Huettner, J. E.; Constantino, J. N.; Kroll, K. L.
10.1101/2020.01.28.922187 — developmental biology — Posted on 2020-05-21
1839 The calcium binding protein S100β marks Hedgehog-responsive perivascular stem cells that contribute to intimal thickening following iatrogenic flow restriction
Di Luca, M.; Fitzpatrick, E.; Burtenshaw, D.; Liu, W.; Helt, J.-C.; Hakimjavadi, R.; Corcoran, E.; Gusti, Y.; Sheridan, D.; Harman, S.; Lally, C.; Redmond, E. M.; Cahill, P. A.
10.1101/2020.05.20.105981 — cell biology — Posted on 2020-05-21
1840 Downregulation of E-cadherin in pluripotent stem cells triggers partial EMT
Aban, C.; Lombardi, A.; Neiman, G.; Biani, M. C.; La Greca, A.; Waisman, A.; Moro, L. N.; Sevlever, G. E.; Miriuka, S. G.; Luzzani, C.
10.1101/2020.05.18.101899 — cell biology — Posted on 2020-05-21
1842 Chemical probe-based Nanopore Sequencing to Selectively Assess the RNA modifications
Ramasamy, S.; Sahayasheela, V. J.; Yu, Z.; Hidaka, T.; Cai, L.; Sugiyama, H.; Pandian, G. N.
10.1101/2020.05.19.105338 — synthetic biology — Posted on 2020-05-21
1843 Effects of genetic variability of CYP2D6 on neural substrates of sustained attention during on-task activity
Viviani, R.; Messina, I.; Bosch, J. E.; Dommes, L.; Paul, A.; Schneider, K. L.; Scholl, C.; Stingl, J. C.
10.1101/831198 — pharmacology and toxicology — Posted on 2020-05-21
1844 Development of follicular dendritic cells in lymph nodes depends on retinoic acid mediated signaling
Koning, J. J.; Rajaraman, A.; Reijmers, R. M.; Konijn, T.; Pan, J.; Ware, C. F.; Butcher, E. C.; Mebius, R. E.
10.1101/2020.05.20.106385 — immunology — Posted on 2020-05-21
1845 Epithelial cell biomarkers are predictive of response to biologic agents in Crohn's disease
Osterman, M.; VanDussen, K.; Gordon, I. O.; Davis, E. M.; Li, K.; Simpson, K.; Ciorba, M.; Abraham, B. P.; Guo, X.; Yee, E.; Allard, F.; Jacqueline G. Perrigoue,, J. G.; Claggett, B.; Shen, B.; Stappenbeck, T. S.; Liu, J. J.
10.1101/2020.05.20.106518 — cell biology — Posted on 2020-05-21
1847 A localization screen reveals translation factories and widespread co-translational RNA targeting
Chouaib, R.; SAFIEDDINE, A.; Pichon, X.; Imbert, A.; Kwon, O. S.; Samacoits, A.; Traboulsi, A.-M.; Robert, M.-C.; Tsanov, N.; Coleno, E.; Poser, I.; Zimmer, C.; Hyman, A. A.; Le Hir, H.; Zibara, K.; Peter, M.; Müller, F.; Walter, T.; Bertrand, E.
10.1101/2020.05.20.106989 — cell biology — Posted on 2020-05-21
1848 Alk1 mutant endothelial cells undergo clonal expansion in mouse brain arteriovenous malformations
Shaligram, S.; Zhang, R.; Zhu, W.; Ma, L.; Winkler, E.; Luo, M.; Li, Q.; Arnold, T.; Santander, N.; M. McDougall, C. M.; Wong, J. Y.; Liang, R.; Barbosa Do Prado, L.; Tang, C.; Su, H.
10.1101/2020.05.20.106799 — cell biology — Posted on 2020-05-21
1850 Micro RNAs are minor constituents of extracellular vesicles and are hardly delivered to target cells
Albanese, M.; Chen, Y.-F. A.; Huels, C.; Gaertner, K.; Tagawa, T.; Keppler, O. T.; Goebel, C.; Zeidler, R.; Hammerschmidt, W.
10.1101/2020.05.20.106393 — cell biology — Posted on 2020-05-21
1854 Loss of PKCα increases arterial medial calcification in a uremic mouse model of chronic kidney disease
Borland, S. J.; Facchi, C.; Behnsen, J.; Adamson, A.; Humphreys, N. E.; Withers, P. J.; Sherratt, M. J.; Francis, S. E.; Brennan, K.; Ashton, N.; Canfield, A. E.
10.1101/2020.05.20.097642 — cell biology — Posted on 2020-05-21
1856 Measuring both microbial load and diversity with a single amplicon sequencing library
Lundberg, D. S.; Pramoj Na Ayutthaya, P.; Strauss, A.; Shirsekar, G.; Lo, W.-S.; Lahaye, T.; Weigel, D.
10.1101/2020.05.19.103937 — bioengineering — Posted on 2020-05-21
1857 Social and endogenous infant vocalizations
Long, H.; Bowman, D.; Yoo, H.; Burkhardt-Reed, M.; Bene, E.; Oller, D. K.
10.1101/821371 — developmental biology — Posted on 2020-05-21
1860 Schistosoma mansoni infection reprograms the metabolic potential of the myeloid lineage in a mouse model of metabolic syndrome
Cortes-Selva, D.; Gibbs, L.; Maschek, J. A.; Van Ry, T.; Rajwa, B.; Cox, J. E.; Amiel, E.; Fairfax, K. C.
10.1101/2020.04.20.050898 — immunology — Posted on 2020-05-21
1861 Population-specific causal disease effect sizes in functionally important regions impacted by selection
Shi, H.; Gazal, S.; Kanai, M.; Koch, E. M.; Schoech, A. P.; Siewert, K. M.; Kim, S. S.; Luo, Y.; Amariuta, T.; Huang, H.; Okada, Y.; Raychaudhuri, S.; Sunyaev, S. R.; Price, A. L.
10.1101/803452 — genetics — Posted on 2020-05-21
1862 Modeling human TBX5 haploinsufficiency predicts regulatory networks for congenital heart disease
Kathiriya, I. S.; Rao, K. S.; Iacono, G.; Devine, W. P.; Blair, A. P.; Hota, S. K.; Lai, M. H.; Garay, B. I.; Thomas, R.; Gong, H. Z.; Wasson, L. K.; Goyal, P.; Sukonnik, T.; Akgun, G. A.; Bernard, L. D.; Akerberg, B. N.; Gu, F.; Li, K.; Pu, W. T.; Stuart, J. M.; Seidman, C. E.; Seidman, J. G.; Heyn, H.; Bruneau, B. G.
10.1101/835603 — developmental biology — Posted on 2020-05-21
1864 The Nucleome Data Bank: Web-based Resources to Simulate and Analyze the Three-Dimensional Genome
Contessoto, V. d. G.; Cheng, R. R.; Hajitaheri, A.; Dodero-Rojas, E.; Mello, M. F.; Aiden, E. L.; Wolynes, P. G.; Di Pierro, M.; Onuchic, J. N.
10.1101/2019.12.20.885145 — bioinformatics — Posted on 2020-05-21
1865 Taxonomically and metabolically distinct microbial communities with depth and across a hillslope to riparian zone transect
Lavy, A.; Matheus Carnevali, P. B.; Keren, R.; Bill, M.; Wan, J.; Tokunaga, T. K.; Williams, K. H.; Hubbard, S. S.; Banfield, J. F.
10.1101/768572 — bioinformatics — Posted on 2020-05-21
1868 Single-cell RNA sequencing reveals functional heterogeneity and sex differences of glioma-associated brain macrophages
Ochocka, N.; Segit, P.; Walentynowicz, K. A.; Wojnicki, K.; Cyranowski, S.; Swatler, J.; Mieczkowski, J.; Kaminska, B.
10.1101/752949 — cancer biology — Posted on 2020-05-20
1869 The landscape of chloroplast genome assembly tools
Freudenthal, J. A.; Pfaff, S.; Terhoeven, N.; Korte, A.; Ankenbrand, M. J.; Foerster, F.
10.1101/665869 — bioinformatics — Posted on 2020-05-20
1871 Timescales of spontaneous fMRI fluctuations relate to structural connectivity in the brain
Fallon, J.; Ward, P.; Parkes, L.; Oldham, S.; Arnatkeviciute, A.; Fornito, A.; Fulcher, B. D.
10.1101/655050 — neuroscience — Posted on 2020-05-20
1872 The developing Human Connectome Project (dHCP) automated resting-state functional processing framework for newborn infants.
Fitzgibbon, S. P.; Harrison, S. J.; Jenkinson, M.; Baxter, L.; Robinson, E. C.; Bastiani, M.; Bozek, J.; Karolis, V.; Cordero Grande, L.; Price, A. N.; Hughes, E.; Makropoulos, A.; Passerat-Palmbach, J.; Schuh, A.; Gao, J.; Farahibozorg, S.-R.; O'Muircheartaigh, J.; Ciarrusta, J.; O'Keeffe, C.; Brandon, J.; Arichi, T.; Rueckert, D.; Hajnal, J. V.; Edwards, A. D.; Smith, S. M.; Duff, E.; Andersson, J.
10.1101/766030 — neuroscience — Posted on 2020-05-20
1875 ActDES- a Curated Actinobacterial Database for Evolutionary Studies
Schniete, J. K.; Selem-Mojica, N.; Birke, A. S.; Cruz-Morales, P.; Hunter, I. S.; Barona-Gomez, F.; Hoskisson, P. A.
10.1101/2020.05.20.105536 — microbiology — Posted on 2020-05-20
1877 Physiologic RNA Targets and Refined Sequence Specificity of Coronavirus EndoU
Ancar, R.; Li, Y.; Kindler, E.; Cooper, D.; Ransom, M.; Thiel, V.; Weiss, S. R.; Hesselberth, J. R.; Barton, D. L.
10.1101/2020.05.20.064436 — microbiology — Posted on 2020-05-20
1878 Quasi-essentiality of RNase Y in Bacillus subtilis is caused by its critical role in the control of mRNA homeostasis
Benda, M.; Woelfel, S.; Gunka, K.; Klumpp, S.; Poehlein, A.; Kalalova, D.; Sanderova, H.; Daniel, R.; Krasny, L.; Stuelke, J.
10.1101/2020.05.20.106237 — microbiology — Posted on 2020-05-20
1879 A single master regulator controls asexual cell cycle division patterns in Toxoplasma gondii
Khelifa, A. S.; Guillen Sanchez, C.; Lesage, K. M.; Huot, L.; Pericard, P.; Barois, N.; Touzet, H.; Marot, G.; GISSOT, M.
10.1101/2020.05.20.095877 — microbiology — Posted on 2020-05-20
1881 Characterizing the response of Acinetobacter baumannii ATCC 17978 to azithromycin in multiple in vitro growth conditions
Dillon, N. A.; Seif, Y.; Tsunemoto, H.; Poudel, S.; Meehan, M.; Szubin, R.; Olson, C.; Rajput, A.; Alarcon, G.; Lamsa, A.; Vrbanac, A.; Sugie, J.; Dahesh, S.; Monk, J.; Dorrestein, P.; Knight, R.; Feist, A.; Pogliano, J.; Palsson, B.; Nizet, V.
10.1101/2020.05.19.079962 — microbiology — Posted on 2020-05-20
1885 Development of diagnostic PCR and LAMP markers for MALE STERILITY 1 (MS1) in Cryptomeria japonica D. Don
Hasegawa, Y.; Ueno, S.; Wei, F.-J.; Matsumoto, A.; Ujino-Ihara, T.; Moriguchi, Y.; Kasahara, M.; Fujino, T.; Shigenobu, S.; Yamaguchi, K.; Bino, T.; Hakamata, T.
10.1101/2020.05.19.090092 — genetics — Posted on 2020-05-20
1887 Cell cycle-gated feedback control mediates desensitization to interferon stimulation
Mudla, A.; Jiang, Y.; Arimoto, K.-i.; Xu, B.; Rajesh, A.; Ryan, A. P.; Wang, W.; Daugherty, M. D.; Zhang, D.-E.; Hao, N.
10.1101/2020.05.18.103101 — systems biology — Posted on 2020-05-20
1890 Morphologic Classification and Automatic Nugent Scoring of Bacterial Vaginosis by Deep Neural Networks
Wang, Z.; Zhang, L.; Wang, Y.; Wang, Y.; Liu, Z.; Bai, H.; Wu, W.; Mo, W.; An, R.; Li, J.; Li, N.; Li, P.; Zeng, X.; Rui, C.; Fan, C.; Geng, L.; Liu, X.; Zhao, M.; Zhu, W.; Qi, L.; Qiao, Q.; Wang, Z.; Si, Y.; Feng, A.; Li, M.; Zhang, Q.; Wang, M.; Liao, Q.; Xu, W.
10.1101/2020.05.20.101055 — microbiology — Posted on 2020-05-20
1891 Human Respiratory Syncytial Virus-induced immune signature of infection revealed by transcriptome analysis of clinical pediatric nasopharyngeal swab samples
Nicolas de Lamballerie, C.; Pizzorno, A.; Dubois, J.; Padey, B.; Julien, T.; Traversier, A.; Carbonneau, J.; Orcel, E.; Lina, B.; Hamelin, M.-E.; Roche, M.; Textoris, J.; Boivin, G.; Legras-Lachuer, C.; Terrier, O.; Rosa-Calatrava, M.
10.1101/2020.05.20.106492 — microbiology — Posted on 2020-05-20
1893 Glyphosate Inhibits Melanization and Increases Insect Susceptibility to Infection
Smith, D. F. Q.; Camacho, E.; Thakur, R.; Barron, A. J.; Broderick, N. A.; Casadevall, A.
10.1101/2020.05.20.105353 — microbiology — Posted on 2020-05-20
1894 Deep sequencing of B cell receptor repertoires from COVID-19 patients reveals strong convergent immune signatures
Galson, J. D.; Schaetzle, S.; Bashford-Rogers, R. J. M.; Raybould, M. I. J.; Kovaltsuk, A.; Kilpatrick, G. J.; Minter, R.; Finch, D. K.; Dias, J.; James, L.; Thomas, G.; Lee, W.-Y. J.; Betley, J.; Cavlan, O.; Leech, A.; Deane, C. M.; Seoane, J.; Caldas, C.; Pennington, D.; Pfeffer, P.; Osbourn, J.
10.1101/2020.05.20.106294 — immunology — Posted on 2020-05-20
1895 In vivo CRISPR screening identifies Fli1 as a transcriptional safeguard that restrains effector CD8 T cell differentiation during infection and cancer
Chen, Z.; Arai, E.; Khan, O.; Zhang, Z.; Ngiow, S. F.; He, Y.; Huang, H.; Manne, S.; Cao, Z.; Baxter, A. E.; Cai, Z.; Freilich, E.; Ali, M. A.; Giles, J. R.; Wu, J. E.; Greenplate, A. R.; Kurachi, M.; Nzingha, K.; Ekshyyan, V.; Wen, Z.; Speck, N. A.; Battle, A.; Berger, S. L.; Wherry, E. J.; Shi, J.
10.1101/2020.05.20.087379 — immunology — Posted on 2020-05-20
1896 A defect in COPI-mediated transport of STING causes immune dysregulation in COPA syndrome
Shum, A. K.; Deng, Z.; Chong, Z.; Law, C. S.; Mukai, K.; Ho, F. O.; Martinu, T.; Backes, B. J.; Eckalbar, W. L.; Taguchi, T.
10.1101/2020.05.20.106500 — immunology — Posted on 2020-05-20
1897 The Southern Bluefin Tuna mucosal microbiome is influenced by husbandry method, net pen location, and anti-parasite treatment
Minich, J. J.; Power, C.; Melanson, M.; Knight, R.; Webber, C.; Rough, K.; Bott, N. J.; Nowak, B.; Allen, E.
10.1101/2020.05.19.105270 — genomics — Posted on 2020-05-20
1898 Intra-host Variation and Evolutionary Dynamics of SARS-CoV-2 Population in COVID-19 Patients
Wang, Y.; Wang, D.; Zhang, L.; Sun, W.; Zhang, Z.; Chen, W.; Zhu, A.; Huang, Y.; Xiao, F.; Yao, J.; Gan, M.; Li, F.; luo, L.; Huang, X.; Zhang, Y.; Wong, S.-s.; Cheng, X.; Ji, J.; Ou, Z.; Xiao, M.; Li, M.; Li, J.; Ren, P.; Deng, Z.; Zhong, H.; Yang, H.; Wang, J.; Xu, X.; Song, T.; Mok, C.; Peiris, M.; Zhong, N.; Zhao, J.; Li, Y.; Li, J.; Zhao, J.
10.1101/2020.05.20.103549 — genomics — Posted on 2020-05-20
1899 In-Vivo Toxicity Studies and In-Vitro Inactivation of SARS-CoV-2 by Povidone-iodine In-situ Gel Forming Formulations
Liang, B.; Yuan, X.; Wei, G.; Wang, W.; Zhang, M.; Peng, H.; Javer, A.; Mendenhall, M.; Julander, J.; Huang, S.; Michail, H.; Lu, Y.; Zhu, Q.; Baldwin, J. J.
10.1101/2020.05.18.103184 — microbiology — Posted on 2020-05-20
1900 A replication-competent vesicular stomatitis virus for studies of SARS-CoV-2 spike-mediated cell entry and its inhibition
Dieterle, M. E.; Haslwanter, D.; Bortz, R. H.; Wirchnianski, A. S.; Lasso, G.; Vergnolle, O.; Abbasi, S. A.; Fels, J. M.; Laudermilch, E.; Florez, C.; Mengotto, A.; Kimmel, D.; Malonis, R. J.; Georgiev, G.; Quiroz, J.; Barnhill, J.; Pirofski, L.-A.; Daily, J. P.; Dye, J. M.; Lai, J. R.; Herbert, A. S.; Chandran, K.; Jangra, R. K.
10.1101/2020.05.20.105247 — microbiology — Posted on 2020-05-20
1901 Dissecting HSV-1-induced host shut-off at RNA level
Friedel, C. C.; Whisnant, A. W.; Djakovic, L.; Rutkowski, A. J.; Friedl, M.-S.; Kluge, M.; Williamson, J. C.; Sai, S.; Vidal, R. O.; Sauer, S.; Hennig, T.; Prusty, B.; Lehner, P. J.; Matheson, N. J.; Erhard, F.; Dölken, L.
10.1101/2020.05.20.106039 — microbiology — Posted on 2020-05-20
1902 Clinical And Analytical Performance Of An Automated Serological Test That Identifies S1/S2 Neutralizing IgG In Covid-19 Patients Semiquantitatively.
Bonelli, F.; Sarasini, A.; Zierold, C.; Calleri, M.; Bonetti, A.; Vismara, C. S.; Blocki, F. A.; Pallavicini, L.; Chinali, A.; Campisi, D.; Percivalle, E.; DiNapoli, A. P.; Perno, C. F.; Balldanti, F.
10.1101/2020.05.19.105445 — immunology — Posted on 2020-05-20
1903 CD8+ T cell cross-reactivity against SARS-CoV-2 conferred by other coronavirus strains and influenza virus
Koohy, H.; Hyun-Jung Lee, C.; Pereira Pinho, M.; Buckley, P.; Woodhouse, I. B.; Ogg, G.; Simmons, A.; Napolitani, G.
10.1101/2020.05.20.107292 — immunology — Posted on 2020-05-20
1905 SARS-CoV-2 targets cortical neurons of 3D human brain organoids and shows neurodegeneration-like effects
Gopalakrishnan, J.; Ramani, A.; Mueller, L.; Niklas Ostermann, P.; Gabriel, E.; Islam Pranty, A.; Mueller-Shiffmann, A.; Mariappan, A.; Goureau, O.; Gruell, H.; Walker, A.; Andree, M.; Hauka, S.; Wohlgemuth, K.; Omran, H.; Klein, F.; Wieczorek, D.; Adams, O.; Timm, J.; Korth, C.; Schaal, H.; Houwaart, T.; Dilthey, A.
10.1101/2020.05.20.106575 — cell biology — Posted on 2020-05-20
1906 A Multiple Peptides Vaccine against nCOVID-19 Designed from the Nucleocapsid phosphoprotein (N) and Spike Glycoprotein (S) via the Immunoinformatics Approach
Abd Albagi, S. O.; Al-Nour, M. Y.; Elhag, M.; Abdelihalim, A. T. I.; Haroun, E. M.; Essa, M. E. A.; Abubaker, M.; Hassan, M. A.
10.1101/2020.05.20.106351 — bioinformatics — Posted on 2020-05-20
1910 Type I and Type III IFN Restrict SARS-CoV-2 Infection of Human Airway Epithelial Cultures
Vanderheiden, A.; Ralfs, P.; Chirkova, T.; Upadhyay, A. A.; Zimmerman, M. G.; Bedoya, S.; Aoued, H.; Tharp, G. K.; Pellegrini, K.; Lowen, A. C.; Menachery, V. D.; Anderson, L. J.; Grakoui, A.; Bosinger, S. E.; Suthar, M. S.
10.1101/2020.05.19.105437 — microbiology — Posted on 2020-05-20
1914 Tiger team: a panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes
Noy-Porat, T.; Makdasi, E.; Alcalay, R.; Mechaly, A.; Levy, Y.; Bercovich-Kinori, A.; Zauberman, A.; Tamir, H.; Yahalom-Ronen, Y.; Israeli, M.; Epstein, E.; Achdout, H.; Melamed, S.; Chitlaru, T.; Weiss, S.; Peretz, E.; Rosen, O.; Paran, N.; Yitzhaki, S.; Shapira, S. C.; Israely, T.; Mazor, O.; Rosenfeld, R.
10.1101/2020.05.20.106609 — immunology — Posted on 2020-05-20
1915 Split-ends is modulating lipid droplet content in adult Drosophila glial cells and is protective against paraquat toxicity.
Girard, V.; Goubard, V.; Querenet, M.; Seugnet, L.; Pays, L.; Nataf, S.; Dufourd, E.; Cluet, D.; Mollereau, B.; Davoust, N.
10.1101/2020.05.20.101220 — neuroscience — Posted on 2020-05-20
1917 CONTAIN: An open-source shipping container laboratory optimisedfor automated COVID-19 diagnostics
Walker, K. T.; Donora, M.; Thomas, A.; Phillips, A. J.; Ramgoolam, K.; Pilch, K. S.; Oberacker, P.; Jurkowski, T. P.; Gosman, R. M.; Fleiss, A.; Perkins, A.; MacKenzie, N.; Zuckerman, M.; Danovi, D.; Steiner, H.; Meany, T.
10.1101/2020.05.20.106625 — molecular biology — Posted on 2020-05-20
1919 Radiosynthesis and Preclinical Evaluation of Ga-NOTA-Folate for PET Imaging of Folate Receptor β Positive Macrophages
Moisio, O.; Palani, S.; Virta, J.; Elo, P.; Liljenback, H.; Tolvanen, T.; Kakela, M.; Miner, M. G.; Atencio Herre, E.; Marjamaki, P.; Ord, T.; Heinaniemi, M.; Kaikkonen-Maatta, M.; Zhang, F.; Srinivasarao, M.; Knuuti, J.; Low, P. S.; Saraste, A.; Li, X.-G.; Roivainen, A.
10.1101/2020.05.18.102483 — biochemistry — Posted on 2020-05-20
1920 Prostaglandin in the ventromedial hypothalamus regulates peripheral glucose metabolism
Lee, M.-L.; Matsunaga, H.; Sugiura, Y.; Hayasaka, T.; Yamamoto, I.; Imoto, D.; Suematsu, M.; Iijima, N.; Kimura, K.; Diano, S.; Toda, C.
10.1101/2020.05.18.056374 — physiology — Posted on 2020-05-20
1921 A Purkinje cell model that simulates complex spikes
Burroughs, A.; Cerminara, N. L.; Apps, R.; Houghton, C. J.
10.1101/2020.05.18.102236 — neuroscience — Posted on 2020-05-20
1923 The AMPK-related kinase NUAK1 controls cortical axons branching though a local modulation of mitochondrial metabolic functions
Lanfranchi, M.; Meyer-Dilhet, G.; Dos Reis, R.; Garcia, A.; Blondet, C.; Javin, L.; Amar, A.; Courchet, J.
10.1101/2020.05.18.102582 — neuroscience — Posted on 2020-05-20
1924 The PAXFOXO1s trigger fast trans-differentiation of chick embryonic neural cells into alveolar rhabdomyosarcoma with tissue invasive properties limited by S phase entry inhibition
GONZALEZ CURTO, G.; Der Vartanian, A.; FRARMA, Y.; Manceau, L.; Baldi, L.; Prisco, S.; ELAROUCI, N.; Causeret, F.; RIGOLET, M.; AURADE, F.; DE REYNIES, A.; CONTREMOULINS, V.; RELAIX, F.; FAKLARIS, O.; BRISCOE, J.; GILARDI-HEBENSTREIT, P.; RIBES, V.
10.1101/2020.05.18.097618 — cancer biology — Posted on 2020-05-20
1926 A unique arginine cluster in PolDIP2 enhances nucleotide binding and DNA synthesis by PrimPol
Kasho, K.; Stojkovic, G.; Velazquez-Ruiz, C.; Martinez-Jimenez, M. I.; Laurent, T.; Perez-Rivera, A. E.; Jenninger, L.; Blanco, L.; Wanrooij, S.
10.1101/2020.05.18.101550 — biochemistry — Posted on 2020-05-20
1929 GATA3 and MDM2 are synthetic lethal in estrogen receptor-positive breast cancers
Bianco, G.; Coto Llerena, M.; Gallon, J.; Taha-Mehlitz, S.; Kancherla, V.; Konantz, M.; Srivatsa, S.; Montazeri, H.; De Menna, M.; Paradiso, V.; Ercan, C.; Beerenwinkel, N.; Kruithof-de Julio, M.; Terracciano, L.; Lengerke, C.; Jeselsohn, R.; Ng, C. K.; Piscuoglio, S.
10.1101/2020.05.18.101998 — cancer biology — Posted on 2020-05-20
1931 Practical gradient non-linearity correction of multi-site diffusion weighted MRI with empirical field maps
Hansen, C. B.; Rogers, B. P.; Schilling, K. G.; Nath, V.; Blaber, J. A.; Irfanoglu, O.; Barnett, A.; Pierpaoli, C.; Anderson, A. W.; Landman, B. A.
10.1101/2020.05.18.102558 — neuroscience — Posted on 2020-05-20
1932 Human es-fMRI Resource: Concurrent deep-brain stimulation and whole-brain functional MRI
Thompson, W. H.; Nair, R.; Oya, H.; Esteban, O.; Shine, J. M.; Petkov, C.; Poldrack, R. A.; Howard, M.; Adolphs, R.
10.1101/2020.05.18.102657 — neuroscience — Posted on 2020-05-20
1933 Genome-wide association study of circulating liver enzymes reveals an expanded role for manganese transporter SLC30A10 in liver health
Ward, L. D.; Tu, H.-C.; Quenneville, C.; Flynn-Carroll, A. O.; Parker, M. M.; Deaton, A. M.; Haslett, P. A. J.; Hinkle, G.; Nioi, P.
10.1101/2020.05.19.104570 — genetics — Posted on 2020-05-20
1936 Cardiac MRI in common marmosets revealing age-dependency of cardiac function
Moussavi, A.; Mietsch, M.; Drummer, C.; Behr, R.; Mylius, J.; Boretius, S.
10.1101/2020.05.18.102020 — zoology — Posted on 2020-05-20
1938 Visualizing the itch-sensing skin arbors
Xing, Y.; Steele, H. R.; Hilley, H. B.; Niehoff, T.; Lawson, K.; Han, L.
10.1101/2020.05.18.098871 — neuroscience — Posted on 2020-05-20
1940 The bear bones: mosaic ancestry of Macaca arctoides explains divergent baculum morphology
Stevison, L.; Szpiech, Z. A.; Bailey, N. P.; Novak, T. E.; Melnick, D. J.; Evans, B. J.; Wall, J. D.
10.1101/2020.05.18.102251 — evolutionary biology — Posted on 2020-05-20
1941 Evolutionary transition to XY sex chromosomes associated with Y-linked duplication of a male hormone gene in a terrestrial isopod
Russell, A.; Borrelli, S.; Fontana, R.; Laricchiuta, J.; Pascar, J.; Becking, T.; Giraud, I.; Cordaux, R.; Chandler, C.
10.1101/2020.05.18.102079 — evolutionary biology — Posted on 2020-05-20
1946 O-Pair Search with MetaMorpheus for O-glycopeptide Characterization
Lu, L.; Riley, N. M.; Shortreed, M. R.; Bertozzi, C. R.; Smith, L. M.
10.1101/2020.05.18.102327 — bioinformatics — Posted on 2020-05-20
1949 DNA from dried blood spots yields high quality sequences for exome analysis
Sunderam, U.; Adhikari, A. N.; Kundu, K.; Puck, J. M.; Currier, R.; Kwok, P.-Y.; Brenner, S. E.; Srinivasan, R.
10.1101/2020.05.19.105304 — genomics — Posted on 2020-05-20
1950 Genome-wide landscape of RNA-binding protein dysregulation reveals a major impact on psychiatric disorder risk
Park, C. Y.; Zhou, J.; Wong, A. K.; Chen, K. M.; Theesfeld, C. L.; Darnell, R.; Troyanskaya, O. G.
10.1101/2020.05.19.102319 — genetics — Posted on 2020-05-20
1953 PrimPol primase mediates replication traverse of DNA interstrand crosslinks
Gonzalez-Acosta, D.; Blanco-Romero, E.; Mutreja, K.; Llanos, S.; Miguez, S.; Garcia, F.; Munoz, J.; Blanco, L.; Lopes, M.; Mendez, J.
10.1101/2020.05.19.104729 — molecular biology — Posted on 2020-05-20
1954 A role for neutral variation in the evolution of C4 photosynthesis
Karki, S.; Lin, H.; Danila, F. R.; AbuJamous, B.; Giuliani, R.; Emms, D. M.; Coe, R. A.; Covshoff, S.; Woodfield, H.; Bagunu, E.; Thakur, V.; Wanchana, S.; Slamet-Loedin, I.; Cousins, A. B.; Hibberd, J. M.; Kelly, S.; Quick, W. P.
10.1101/2020.05.19.104299 — plant biology — Posted on 2020-05-20
1955 In-cell quantitative structural imaging of phytoplankton using 3D electron microscopy
Uwizeye, C.; Decelle, J.; Jouneau, P.-H.; Gallet, B.; Keck, J.-B.; Moriscot, C.; Chevalier, F.; Schieber, N. L.; Templin, R.; Curien, G.; Schwab, Y.; Schoehn, G.; Zeeman, S. C.; Falconet, D.; Finazzi, G.
10.1101/2020.05.19.104166 — plant biology — Posted on 2020-05-20
1959 Structure and Evolution of Constitutive Bacterial Promoters
Lagator, M.; Sarikas, S.; Steinrück, M.; Toledo-Aparicio, D.; Bollback, J. P.; Tkacik, G.; Guet, C. C.
10.1101/2020.05.19.104232 — evolutionary biology — Posted on 2020-05-20
1960 UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFRsignaling
TORRINO, S.; TIROILLE, V.; DOLFI, B.; DUFIES, M.; HINAULT, C.; BONESSO, L.; DAGNINO, S.; UHLER, J. P.; IRONDELLE, M.; GAY, A.-S.; FLEURIOT, L.; Debayle, D.; LACAS-GERVAIS, S.; CORMONT, M.; BERTERO, T.; BOST, F.; GILLERON, J.; CLAVEL, S.
10.1101/2020.05.20.105775 — cell biology — Posted on 2020-05-20
1961 Novel insights into the structure and transport mechanisms of TAPT1
Parvez, M. S. A.; Rahman, M. M.; Morshed, M. N.; Rahman, D.; Anwar, S.; Coucke, P.; Hosen, M. J.
10.1101/2020.05.18.099887 — biochemistry — Posted on 2020-05-20
1962 Alterations in resting-state network dynamics along the Alzheimer's disease continuum: a combined MEG-PET/MR approach
Puttaert, D.; Coquelet, N.; Wens, V.; Peigneux, P.; Fery, P.; Rovai, A.; Trotta, N.; Bier, J.-C.; Goldman, S.; De Tiege, X.
10.1101/2020.05.18.101683 — neuroscience — Posted on 2020-05-20
1965 A singleton NLR of recent origin causes hybrid necrosis in Arabidopsis thaliana
Barragan, A. C.; Collenberg, M.; Wang, J.; Lee, R. R. Q.; Cher, W. Y.; Rabanal, F. A.; Ashkenazy, H.; Weigel, D.; Chae, E.
10.1101/2020.05.18.101451 — evolutionary biology — Posted on 2020-05-20
1966 In silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor
Ariey-Bonnet, J.; Carrasco, K.; Le Grand, M.; Hoffer, L.; Betzi, S.; Feracci, M.; Tsvetkov, P.; Devred, F.; Collette, Y.; Morelli, X.; Ballester, P.; Pasquier, E.
10.1101/2020.05.18.101329 — pharmacology and toxicology — Posted on 2020-05-20
1969 Dynamic proteomics profiling of Legionella pneumophila infection unveils modulation of the host mitochondrial stress response pathway
Noack, J.; Jimenez-Morales, D.; Stevenson, E.; Moss, T.; Jang, G. M.; Krogan, N. J.; Swaney, D. L.; Mukherjee, S.
10.1101/2020.05.19.105395 — cell biology — Posted on 2020-05-20
1975 Identification of Avramr1 from Phytophthora infestans using long read and cDNA pathogen-enrichment sequencing (PenSeq)
Lin, X.; Song, T.; Fairhead, S.; Witek, K.; Jouet, A.; Jupe, F.; Witek, A. I.; Karki, H. S.; Vleeshouwers, V. G. A. A.; Hein, I.; Jones, J. D. G.
10.1101/2020.05.14.095158 — genomics — Posted on 2020-05-20
1979 Small molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer's disease
Heller, G. T.; Aprile, F. A.; Michaels, T. C.; Limbocker, R.; Perni, M.; Ruggeri, F. S.; Mannini, B.; Lohr, T.; Bonomi, M.; Camilloni, C.; De Simone, A.; Felli, I. C.; Pierattelli, R.; Knowles, T. P.; Dobson, C. M.; Vendruscolo, M.
10.1101/729392 — biophysics — Posted on 2020-05-20
1980 Dynamic meta-analysis: a method of using global evidence for local decision making
Shackelford, G. E.; Martin, P. A.; Hood, A. S. C.; Christie, A. P.; Kulinskaya, E.; Sutherland, W. J.
10.1101/2020.05.18.078840 — ecology — Posted on 2020-05-20
1984 Biomineral armor in leaf-cutter ants
Li, H.; Sun, C.-Y.; Fang, Y.; Carlson, C. M.; Xu, H.; Jesovnik, A.; Sosa-Calvo, J.; Zarnowski, R.; Bechtel, H. A.; Fournelle, J. H.; Andes, D. R.; Schultz, T.; Gilbert, P. U. P. A.; Currie, C. R.
10.1101/2020.05.18.102962 — biophysics — Posted on 2020-05-20
1986 TraIT, Translational research IT bridging the valley of death in translational medicine
Boiten, J.-W.; Azevedo, R.; van Bochove, K.; Cavelaars, M.; Dekker, A.; Fijneman, R. J. A.; Lansberg, P.; van der Linden, W.; Mons, B.; Stathonikos, N.; Verheul, H. M. W.; Beliën, J. A. M.; Meijer, G. A.
10.1101/2020.05.18.052563 — bioinformatics — Posted on 2020-05-20
1991 Transcription factor PU.1 enforces quiescence and limits hematopoietic stem cell expansion during inflammatory stress
Chavez, J. S.; Rabe, J. L.; Loeffler, D.; Higa, K.; Hernandez, G.; Mills, T. S.; Ahmed, N.; Gessner, R. L.; Ke, Z.; Idler, B. M.; Kim, H. M.; Myers, J. R.; Stevens, B. M.; Jordan, C. T.; Nakajima, H.; Ashton, J.; Welner, R. S.; Schroeder, T.; DeGregori, J.; Pietras, E. M.
10.1101/2020.05.18.102830 — immunology — Posted on 2020-05-20
1992 Infrared fiber optic spectroscopy detects bovine articular cartilage degeneration
Virtanen, V. K. O.; Nippolainen, E.; Shaikh, R.; Afara, I.; Toyras, J.; Solheim, J.; Tafintseva, V.; Zimmermann, B.; Kohler, A.; Saarakkala, S.; Rieppo, L.
10.1101/2020.05.18.101600 — biophysics — Posted on 2020-05-20
1994 Protective role of neuronal and lymphoid cannabinoid CB2 receptors in neuropathic pain
Cabanero, D.; Ramirez-Lopez, A.; Drews, E.; Schmöle, A.; Otte, D. M.; Wawrzczak-Bargiela, A.; Huerga Encabo, H.; Kummer, S.; Przewlocki, R.; Zimmer, A.; Maldonado, R.
10.1101/2020.05.19.103580 — physiology — Posted on 2020-05-20
1995 Genome-wide effects of the antimicrobial peptide apidaecin on translation termination
Vazquez-Laslop, N.; Mankin, A.; FLorin, T.; Mangano, K.; Shao, X.; Klepacki, D.; Chelysheva, I.; Ignatova, Z.; Gao, Y.
10.1101/2020.05.17.100735 — biochemistry — Posted on 2020-05-20
1997 EHBP1 and EHD2 regulate Dll4 caveolin-mediated endocytosis during blood vessel development
Webb, A. M.; Francis, C. R.; Webb, J. M.; Kincross, H.; Lundy, K. M.; Judson, R.; Meadows, S. M.; Kushner, E. J.
10.1101/2020.05.19.104547 — cell biology — Posted on 2020-05-20
1998 Local RNA translation controls cell migration and Rab GTPase function
Moissoglu, K.; Stueland, M.; Gasparski, A. N.; Wang, T.; Jenkins, L. M.; Hastings, M. L.; Mili, S.
10.1101/2020.05.19.104463 — cell biology — Posted on 2020-05-20
2000 Discrete regulation of b-catenin-mediated transcription governs identity of intestinal epithelial stem cells
Borrelli, C.; Valenta, T.; Handler, K.; Velez, K.; Moro, G.; Lafzi, A.; de Vargas Roditi, L.; Hausmann, G.; Moor, A. E.; Basler, K.
10.1101/2020.05.19.103499 — cell biology — Posted on 2020-05-20
2002 K-fiber bundles in the mitotic spindle are mechanically reinforced by Kif15
Begley, M. A.; Solon, A. L.; Davis, E. M.; Sherrill, M. G.; Ohi, R.; Elting, M. W.
10.1101/2020.05.19.104661 — cell biology — Posted on 2020-05-20
2004 A Connectivity-based Psychometric Prediction Framework for Brain-behavior Relationship Studies
Wu, J.; Eickhoff, S. B.; Hoffstaedter, F.; Patil, K. R.; Schwender, H.; Yeo, B. T. T.; Genon, S.
10.1101/2020.01.15.907642 — neuroscience — Posted on 2020-05-20
2006 Circadian clock mechanism driving mammalian photoperiodism
Wood, S. H.; Hindle, M. H.; Mizoro, Y.; Cheng, Y.; Saer, B. R.; Miedzinska, K.; Christian, H. C.; Begley, N.; McNeilly, J.; McNeilly, A. S.; Meddle, S.; Burt, D. W.; Loudon, A. S.
10.1101/2020.05.19.102194 — molecular biology — Posted on 2020-05-20
2007 Host genetic and environmental factors shape the human gut resistome
Le Roy, C. I.; Bowyer, R. C.; Carr, V. R.; Costeira, R.; Castillo-Fernandez, J. E. R.; Martin, T. C.; Spector, T.; Steves, C.; Moyes, D.; Forslund, S. K.; Bell, J. T.
10.1101/2020.05.18.092973 — microbiology — Posted on 2020-05-20
2008 Modification of forests by people means only 40% of remaining forests have high ecosystem integrity
Grantham, H. S.; Duncan, A.; Evans, T. D.; Jones, K. R.; Beyer, H.; Schuster, R.; Walston, J.; Ray, J.; Robinson, J.; Callow, M.; Clements, T.; Costa, H.; DeGemmis, A.; Elsen, P. R.; Ervin, J.; Franco, P.; Goldman, E.; Goetz, S.; Hansen, A.; Hofsvang, E.; Jantz, P.; Jupiter, S.; Kang, A.; Langhammer, P.; Laurance, W. F.; Liberman, S.; Linkie, M.; Malhi, Y.; Maxwell, S. L.; Mendez, M.; Mittermeier, R.; Murray, N.; Possingham, H.; Radachowsky, J.; Samper, C.; Silverman, J.; Shapiro, A.; Strassburg, B.; Stevens, T.; Stokes, E.; Taylor, R.; Tear, T.; Tizard, R.; Venter, O.; Visconti, P.; Wang, S.;
10.1101/2020.03.05.978858 — ecology — Posted on 2020-05-20
2011 Non-canonical proline-tyrosine interactions with multiple host proteins regulate Ebola virus infection
Batra, J.; Anantpadma, M.; Small, G. I.; Shtanko, O.; Zhang, M.; Liu, D.; Williams, C. G.; Biedenkopf, N.; Becker, S.; Gross, M. L.; Leung, D. W.; Davey, R. A.; Amarasinghe, G. K.; Krogan, N. J.; Basler, C. F.
10.1101/2020.05.19.102954 — microbiology — Posted on 2020-05-20
2012 Tissue-specific multiOMICs analysis of atrial fibrillation
Assum, I.; Krause, J.; Scheinhardt, M. O.; Hammer, E.; Mueller, C.; Boerschel, C. S.; Voelker, U.; Conradi, L.; Geelhoed, B.; Zeller, T.; Schnabel, R.; Heinig, M.
10.1101/2020.04.06.021527 — genetics — Posted on 2020-05-20
2017 Metagenomic profiling of ammonia- and methane-oxidizing microorganisms in a Dutch drinking water treatment plant
Poghosyan, L.; Koch, H.; Frank, J.; van Kessel, M. A. H. J.; Cremers, G.; van Alen, T.; Jetten, M. S. M.; Op den Camp, H. J. M.; Luecker, S.
10.1101/2020.05.19.103440 — microbiology — Posted on 2020-05-20
2018 A draft genome assembly of the eastern banjo frog Limnodynastes dumerilii dumerilii (Anura: Limnodynastidae)
Li, Q.; Guo, Q.; Zhou, Y.; Tan, H.; Bertozzi, T.; Zhu, Y.; Li, J.; Donnellan, S.; Zhang, G.
10.1101/2020.03.03.971721 — genomics — Posted on 2020-05-20
2022 HIV-1 RNA genomes initiate host protein packaging in the cytosol independently of Gag capsid proteins
Becker, J. T.; Evans, E. L.; Benner, B. E.; Pritzl, S. L.; Smith, L. E.; Bates, A. E.; Sherer, N. M.
10.1101/846105 — cell biology — Posted on 2020-05-20
2024 Plasma and Fecal Metabolite Profiles in Autism Spectrum Disorder
Needham, B. D.; Adame, M. D.; Serena, G.; Rose, D. R.; Preston, G. M.; Conrad, M. C.; Campbell, A. S.; Donabedian, D. H.; Fasano, A.; Ashwood, P.; Mazmanian, S. K.
10.1101/2020.05.17.098806 — biochemistry — Posted on 2020-05-20
2026 Circadian Rhythms of Perineuronal Net Composition
Pantazopoulos, H.; Gisabella, B.; Rexrode, L.; Benefield, D.; Yildiz, E.; Seltzer, P.; Valeri, J.; Chelini, G.; Reich, A.; Ardelt, M.; Berretta, S.
10.1101/2020.04.21.053751 — neuroscience — Posted on 2020-05-20
2027 Endocannabinoids and dopamine balance basal ganglia output
Gorodetski, L.; Loewenstern, Y.; Faynveitz, A.; Bar-Gad, I.; Blackwell, K. T.; Korngreen, A.
10.1101/2020.05.18.099341 — neuroscience — Posted on 2020-05-20
2028 Nonlinear convergence preserves information
Gutierrez, G. J.; Rieke, F.; Shea-Brown, E.
10.1101/811539 — neuroscience — Posted on 2020-05-20
2029 Histone deposition pathways determine the chromatin landscapes of H3.1 and H3.3 K27M oncohistones
Sarthy, J. F.; Meers, M. P.; Janssens, D.; Henikoff, J. G.; Morris, S.; Biery, M.; Feldman, H.; Paddison, P. J.; Vitanza, N.; Olson, J. M.; Ahmad, K.; Henikoff, S.
10.1101/2020.05.18.101709 — molecular biology — Posted on 2020-05-20
2030 The importance of orangutans in small fragments for maintaining metapopulation dynamics
Ancrenaz, M.; Oram, F.; Nardiyono, N.; Silmi, M.; Jopony, M. E. M.; Voigt, M.; Seaman, D. J. I.; Sherman, J.; Lackman, I.; Traeholt, C.; Wich, S.; Struebig, M. J.; Santika, T.; Meijaard, E.
10.1101/2020.05.17.100842 — ecology — Posted on 2020-05-20
2031 A Chemical-genetics and Nanoparticle Enabled Approach for in vivo Protein Kinase Analysis
Chen, F.; Liu, Q.; Hilliard, T.; Wang, T.; Liang, H.; Gao, W.; Huang, L.; Wang, D.
10.1101/2020.05.13.094573 — cell biology — Posted on 2020-05-20
2032 Nek8445, a protein kinase required for microtubule regulation and cytokinesis in Giardia lamblia
Hennessey, K. M.; Alas, G. C. M.; Rogiers, I.; Li, R.; Merritt, E. A.; Paredez, A. R.
10.1101/719005 — cell biology — Posted on 2020-05-20
2034 Predictive Patterns of Antidepressant Response from Pre-Treatment Reward Processing using Functional MRI and Deep Learning: Key Results from the EMBARC Randomized Clinical Trial
Nguyen, K. P.; Chin Fatt, C.; Treacher, A.; Mellema, C.; Cooper, C.; Jha, M.; Kurian, B.; Fava, M.; McGrath, P. J.; Weissman, M.; Phillips, M. L.; Trivedi, M. H.; Montillo, A.
10.1101/2020.01.28.923821 — bioinformatics — Posted on 2020-05-20
2036 Spontaneous restoration of functional β-cell mass in obese SM/J mice
Miranda, M. A.; Carson, C.; St Pierre, C. L.; Macias-Velasco, J. F.; Hughes, J. W.; Kunzmann, M.; Schmidt, H.; Wayhart, J. P.; Lawson, H. A.
10.1101/2020.05.19.104588 — physiology — Posted on 2020-05-20
2037 Spontaneous variability in gamma dynamics described by a linear harmonic oscillator driven by noise
Spyropoulos, G.; Dowdall, J. R.; Scholvinck, M. L.; Bosman, C. A.; Lima, B.; Peter, A.; Onorato, I.; Klon-Lipok, J.; Roese, R.; Neuenschwander, S.; Singer, W.; Vinck, M.; Fries, P.
10.1101/793729 — neuroscience — Posted on 2020-05-20
2038 Skill learning can be independent of speed and accuracy instructions
Vekony, T.; Marossy, H.; Must, A.; Vecsei, L.; Janacsek, K.; Nemeth, D.
10.1101/726315 — neuroscience — Posted on 2020-05-20
2039 Population genomics and antimicrobial resistance in Corynebacterium diphtheriae
Hennart, M.; Panunzi, L. G.; Rodrigues, C.; Gaday, Q.; Baines, S. L.; Barros-Pinkelnig, M.; Carmi-Leroy, A.; Dazas, M.; Wehenkel, A.-M.; Didelot, X.; Toubiana, J.; Badell, E.; Brisse, S.
10.1101/2020.05.19.101030 — microbiology — Posted on 2020-05-20
2040 An ex vivo model of Toxoplasma recrudescence
Goerner, A. L.; Vizcarra, E. A.; Hong, D. D.; Bergersen, K. V.; Alvarez, C. A.; Talavera, M. A.; Wilson, E. H.; White, M. W.
10.1101/2020.05.18.101931 — microbiology — Posted on 2020-05-20
2043 Mate-finding dispersal reduces local mate limitation and sex bias in dispersal
Mishra, A.; Tung, S.; Shree Sruti, V. R.; Srivathsa, S.; Dey, S.
10.1101/770412 — ecology — Posted on 2020-05-20
2046 Wakefulness fluctuations elicit behavioural and neural reconfiguration of awareness
Noreika, V.; Canales-Johnson, A.; Johnson, A.; Arnatkeviciute, A.; Koh, J.; Chennu, S.; Bekinschtein, T. A.
10.1101/155705 — neuroscience — Posted on 2020-05-20
2047 Seizure-associated spreading depression is a major feature of ictal events in two animal models of chronic epilepsy
Bahari, F.; Ssentongo, P.; Liu, J.; Kimbugwe, J.; Curay, C.; Schiff, S. J.; Gluckman, B. J.
10.1101/455519 — neuroscience — Posted on 2020-05-20
2048 Role of Inflammasome-independent Activation of IL-1β by the Pseudomonas aeruginosa Protease LasB
Sun, J.; LaRock, D.; Skowronski, E.; Kimmey, J. M.; Olson, J.; Jiang, Z.; O'Donoghue, A.; Nizet, V.; LaRock, C.
10.1101/2020.05.18.101303 — microbiology — Posted on 2020-05-19
2049 Integration of machine learning and pan-genomics expands the biosynthetic landscape of RiPP natural products
Kloosterman, A. M.; Cimermancic, P.; Elsayed, S. S.; Du, C.; Hadjithomas, M.; Donia, M. S.; Fischbach, M. A.; van Wezel, G. P.; Medema, M. H.
10.1101/2020.05.19.104752 — microbiology — Posted on 2020-05-19
2055 Monitoring the microbiome for food safety and quality using deep shotgun sequencing
Beck, K. L.; Haiminen, N.; Chambliss, D.; Edlund, S. B.; Kunitomi, M.; Huang, B. C.; Kong, N.; Ganesan, B.; Baker, R.; Markwell, P.; Kawas, B.; Davis, M.; Prill, R. J.; Krishnareddy, H.; Seabolt, E.; Marlowe, C. H.; Pierre, S.; Quintanar, A.; Parida, L.; Dubois, G.; Kaufman, J.; Weimer, B. C.; Consortium for Sequencing the Food Supply Chain,
10.1101/2020.05.18.102574 — microbiology — Posted on 2020-05-19
2056 Mud, microbes, and macrofauna: seasonal dynamics of the iron biogeochemical cycle in an intertidal mudflat
Beam, J. P.; George, S.; Record, N. R.; Countway, P. D.; Johnston, D. T.; Girguis, P. R.; Emerson, D.
10.1101/2020.05.18.100800 — microbiology — Posted on 2020-05-19
2057 Molecular Mechanism for Rotational Switching of the Bacterial Flagellar Motor
Chang, Y.; Zhang, K.; Carroll, B.; Zhao, X.; Charon, N. W.; Norris, S. J.; Motaleb, M. A.; Li, C.; Liu, J.
10.1101/2020.05.18.101634 — microbiology — Posted on 2020-05-19
2058 SERINC5 potently restricts retrovirus infection in vivo
Timilsina, U.; Umthong, S.; Lynch, B.; Stablewski, A.; Stavrou, S.
10.1101/2020.05.19.102798 — microbiology — Posted on 2020-05-19
2064 Phytoplankton trigger the production of cryptic metabolites in the marine actinobacteria Salinispora tropica
Chhun, A.; Sousoni, D.; Aguilo-Ferretjans, M. d. M.; Song, L.; Corre, C.; Christie-Oleza, J. A.
10.1101/2020.05.18.103358 — microbiology — Posted on 2020-05-20
2068 Human IgG cell neutralizing monoclonal antibodies block SARS-CoV-2 infection
Lan, F.; Xu, J.; Lu, Y.; Wan, J.; Xing, S.; Wang, Y.; Ding, L.; Yuan, S.; Qiu, C.; Zhao, C.; Zhang, X.; Wang, X.
10.1101/2020.05.19.104117 — immunology — Posted on 2020-05-19
2069 Multi-Antigenic Virus-like Particle of SARS CoV-2 produced in Saccharomyces cerevisiae as a vaccine candidate
Arora, K.; Rastogi, R.; Arora, N. M.; Parashar, D.; Paliwal, J.; Naqvi, A.; Srivastava, A.; Singh, S. K.; Kalyanaraman, S.; Potdar, S.; Kumar, D.; Arya, V. B.; Bansal, S.; Rautray, S.; Singh, I.; Fengade, P. S.; Kumar, B.; Kundu, P. K.
10.1101/2020.05.18.099234 — biochemistry — Posted on 2020-05-19
2071 Antiviral activity of Glucosylceramide synthase inhibitors against SARS-CoV-2 and other RNA virus infections
Vitner, E. B.; Avraham, R.; Achdout, H.; Tamir, H.; Agami, A.; Cherry, L.; Yahalom-Ronen, Y.; Politi, B.; Erez, N.; Melamed, S.; Paran, N.; Israely, T.
10.1101/2020.05.18.103283 — microbiology — Posted on 2020-05-19
2072 The impact of super-spreaders in COVID-19: mapping genome variation worldwide
Gomez-Carballa, A.; Bello, X.; Pardo-Seco, J.; Martinon-Torres, F.; Salas, A.
10.1101/2020.05.19.097410 — genomics — Posted on 2020-05-19
2073 Emerging phylogenetic structure of the SARS-CoV-2 pandemic
Fountain-Jones, N. M.; Carol Appaw, R.; Carver, S.; Didelot, X.; Volz, E. M.; Charleston, M.
10.1101/2020.05.19.103846 — genetics — Posted on 2020-05-19
2075 Transcriptional profiling of immune and inflammatory responses in the context of SARS-CoV-2 fungal superinfection in a human airway epithelial model
Nicolas de Lamballerie, C.; Pizzorno, A.; Fouret, J.; szpiro, L.; Padey, B.; Dubois, J.; Julien, T.; Traversier, A.; Duliere, V.; Brun, P.; Lina, B.; Rosa-Calatrava, M.; Terrier, O.
10.1101/2020.05.19.103630 — microbiology — Posted on 2020-05-19
2078 A ChIC solution for ChIP-seq quality assessment
Livi, C. M.; Tagliaferri, I.; Pal, K.; Sebestyen, E.; Lucini, F.; Bianchi, A.; Valsoni, S.; Lanzuolo, C.; Ferrari, F.
10.1101/2020.05.19.103887 — bioinformatics — Posted on 2020-05-19
2082 Using targeted genome integration for virus-free genome-wide mammalian CRISPR screen
Xiong, K.; Karottki, K. J. L.; Hefzi, H.; Li, S.; Grav, L. M.; Li, S.; Spahn, P.; Lee, J. S.; Lee, G. M.; Kildegaard, H. F.; Lewis, N. E.; Pedersen, L. E.
10.1101/2020.05.19.103648 — genomics — Posted on 2020-05-19
2083 Short- and long-read metagenomics of South African gut microbiomes reveal a transitional composition and novel taxa
Tamburini, F. B.; Maghini, D.; Oduaran, O. H.; Brewster, R.; Hulley, M. R.; Sahibdeen, V.; Norris, S. A.; Tollman, S.; Kahn, K.; Wagner, R.; Wade, A. N.; Wafawanaka, F.; Gomez-Olive, X.; Twine, R.; Lombard, Z.; Hazelhurst, S.; Bhatt, A. S.
10.1101/2020.05.18.099820 — genomics — Posted on 2020-05-19
2084 Kinship, acquired and inherited status, and population structure at the Early Bronze Age Mokrin necropolis in northern Serbia.
Zegarac, A.; Winkelbach, L.; Bloecher, J.; Diekmann, Y.; Kreckovic Gavrilovic, M.; Porcic, M.; Stojkovic, B.; Milasinovic, L.; Schreiber, M.; Wegmann, D.; Veeramah, K. R.; Stefanovic, S.; Burger, J.
10.1101/2020.05.18.101337 — genomics — Posted on 2020-05-19
2085 A rapid, sensitive, scalable method for Precision Run-On sequencing (PRO-seq)
Judd, J.; Wojenski, L. A.; Wainman, L. M.; Tippens, N. D.; Rice, E. J.; Dziubek, A.; Villafano, G. J.; Wissink, E. M.; Versluis, P.; Bagepalli, L.; Shah, S. R.; Mahat, D. B.; Tome, J. M.; Danko, C. G.; Lis, J. T.; Core, L. J.
10.1101/2020.05.18.102277 — genomics — Posted on 2020-05-19
2086 AnAms1.0: A high-quality chromosome-scale assembly of a domestic cat Felis catus of American Shorthair breed
Isobe, S.; Matsumoto, Y.; Chung, C.; Sakamoto, M.; Chan, T.; Hirakawa, H.; Ishihara, G.; Lam, H.-M.; Nakayama, S.; Sasamoto, S.; Tanizawa, Y.; Watanabe, A.; Watanabe, K.; Yagura, M.; Nakamura, Y.
10.1101/2020.05.19.103788 — genomics — Posted on 2020-05-19
2087 Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development
Geusz, R. J.; Wang, A.; Chiou, J.; Lancman, J. J.; Wetton, N.; Kefalopoulou, S.; Wang, J.; Qiu, Y.; Yan, J.; Aylward, A.; Ren, B.; Dong, P. D. S.; Gaulton, K. J.; Sander, M.
10.1101/2020.05.18.101071 — genomics — Posted on 2020-05-19
2090 Resistance to pirimiphos-methyl in West African Anopheles is spreading via duplication and introgression of the Ace1 locus
Grau-Bove, X.; Lucas, E. R.; Pipini, D.; Rippon, E.; van't Hof, A.; Constant, E.; Dadzie, S.; Egyir-Yawson, A.; Essandoh, J.; Chabi, J.; Djogbenou, L.; Harding, N. J.; Miles, A.; Kwiatkowski, D.; Donnelly, M. J.; Weetman, D.; The Anopheles gambiae 1000 Genomes Consortium,
10.1101/2020.05.18.102343 — genomics — Posted on 2020-05-19
2092 Deciphering the genetic diversity of landraces with high-throughput SNP genotyping of DNA bulks: methodology and application to the maize 50k array
Arca, M.; Mary-Huard, T. D.; Gouenard, B.; Berard, A.; Bauland, C.; Combes, V.; Madur, D.; Charcosset, A.; Nicolas, S. D.
10.1101/2020.05.19.103655 — genetics — Posted on 2020-05-19
2093 Paternal multigenerational exposure to an obesogenic diet drives epigenetic predisposition to metabolic disorders
Raad, G.; Serra, F.; Martin, L.; Derieppe, M.-A.; Gilleron, J.; Costa, V. L.; Pisani, D. F.; Amri, E.-Z.; Trabucchi, M.; Grandjean, V.
10.1101/2020.05.19.104075 — genetics — Posted on 2020-05-19
2095 Targeted Next-Generation Sequencing Identifies Pathogenic Variants in Kidney Disease-Related Genes in Patients with Diabetic Kidney Disease
Lazaro Guevara, J. M.; Pezzolesi, M. G.; Fierro, J.; Wright, H. A.; Gunville, R.; frodsham, s. G.; Pezzolesi, M. H.; Zaffino, C.; Al-Rabadi, L.; Ramkumar, N.
10.1101/2020.05.18.102822 — genetics — Posted on 2020-05-19
2096 Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis
Mousavy-Gharavy, N. S.; Owen, B.; Millership, S. J.; Chabosseau, P.; Pizza, G.; Martinez-Sanchez, A.; Tasoez, E.; Georgiadou, E.; Hu, M.; Fine, N. H. F.; Jacobson, D. A.; Dickerson, M.; Idevall, O.; Montoya, A.; Kramer, H.; Mehta, Z.; Withers, D.; Ninov, N.; Gadue, P.; Cardenas-Diaz, F. L.; Cruciani-Guglielmacci, C.; Magnan, C.; Ibberson, M.; Leclerc, I.; Voz, M.; Rutter, G. A.
10.1101/2020.05.18.099200 — genetics — Posted on 2020-05-19
2097 The impact of global and local Polynesian genetic ancestry on complex traits in Native Hawaiians
Sun, H.; Lin, M.; Russell, E. M.; Minster, R. L.; Chan, T. F.; Naseri, T.; Reupena, M. S.; Lum-Jones, A.; the Samoan Obesity, Lifestyle, and Genetic Adaptations (OLaGA) Study Group, ; Cheng, I.; Wilkens, L. R.; Le Marchand, L.; Haiman, C. A.; Chiang, C. W. K.
10.1101/2020.05.18.102996 — genetics — Posted on 2020-05-19
2099 Awakening a latent carbon fixation cycle in Escherichia coli
Satanowski, A.; Dronsella, B.; Noor, E.; Vögeli, B.; He, H.; Wichmann, P.; Erb, T. J.; Lindner, S. N.; Bar-Even, A.
10.1101/2020.05.18.102244 — synthetic biology — Posted on 2020-05-19
2100 ITPK1 is an InsP6/ADP phosphotransferase that controls systemic phosphate homeostasis in Arabidopsis
Riemer, E.; Laha, D.; Harmel, R. K.; Gaugler, P.; Pries, V.; Frei, M.; Hajirezaei, M. R.; Laha, N. P.; Krusenbaum, L.; Schneider, R.; Jessen, H. J.; Saiardi, A.; Fiedler, D.; Schaaf, G.; Giehl, R. F. H.
10.1101/2020.05.18.100297 — plant biology — Posted on 2020-05-19
2101 The minor and major spliceosome interact to regulate alternative splicing around minor introns
Olthof, A. M.; White, A. K.; Lee, M. F.; Chakroun, A.; Abdel Aleem, A. K.; Rousseau, J.; Magnani, C.; Campeau, P. M.; Kanadia, R. N.
10.1101/2020.05.18.101246 — molecular biology — Posted on 2020-05-19
2105 Developmental Normalization of Phenomics Data Generated by High Throughput Plant Phenotyping Systems
Lozano-Claros, D.; Meng, X.; Custovic, E.; Deng, G.; Berkowitz, O.; Whelan, J.; Lewsey, M. G.
10.1101/2020.05.17.100917 — plant biology — Posted on 2020-05-19
2110 The importance of orangutans in small fragments for maintaining metapopulation dynamics
Ancrenaz, M.; Oram, F.; Nardiyono, N.; Silmi, M.; Jopony, M. E. M.; Voigt, M.; Seaman, D. J. I.; Sherman, J.; Lackman, I.; Traeholt, C.; Wich, S.; Struebig, M. J.; Santika, T.; Meijaard, E.
10.1101/2020.05.17.100842 — ecology — Posted on 2020-05-19
2113 Plasma and Fecal Metabolite Profiles in Autism Spectrum Disorder
Needham, B. D.; Adame, M. D.; Serena, G.; Rose, D. R.; Preston, G. M.; Conrad, M. C.; Campbell, A. S.; Donabedian, D. H.; Fasano, A.; Ashwood, P.; Mazmanian, S. D.
10.1101/2020.05.17.098806 — biochemistry — Posted on 2020-05-19
2115 Human Hair Graying is Naturally Reversible and Linked to Stress
Rosenberg, A.; Rausser, S.; Ren, J.; Mosharov, E.; Sturm, G. M.; Ogden, R. T.; Patel, P.; Soni, R. K.; Lacefield, C.; Paus, R.; Picard, M.
10.1101/2020.05.18.101964 — cell biology — Posted on 2020-05-19
2117 Talin Rod Domain Containing Protein 1 (TLNRD1) is a novel actin- bundling protein which promotes filopodia formation
Cowell, A. R.; Jacquemet, G.; Singh, A. K.; Ammon, Y.-C.; Brown, D. G.; Akhmanova, A.; Ivaska, J.; Goult, B. T.
10.1101/2020.05.19.103606 — cell biology — Posted on 2020-05-19
2119 Integrative proteomics reveals principles of dynamic phospho-signaling networks in human erythropoiesis
Karayel, O.; Xu, P.; Bludau, I.; Bhoopalan, S. V.; Yao, Y.; Freitas Colaco, A. R.; Santos Delgado, A.; Schulman, B. A.; Alpi, A. F.; Weiss, M. J.; Mann, M.
10.1101/2020.05.18.102178 — systems biology — Posted on 2020-05-19
2120 ASYMMETRIC EXPRESSION OF ARGONAUTES IN ARABIDOPSIS REPRODUCTIVE TISSUES
jullien, p. E.; Bonnet, D. M.; Pumplin, N.; Schroeder, J. A.; Voinnet, O.
10.1101/2020.05.18.102863 — developmental biology — Posted on 2020-05-19
2121 Human iPSC-derived hypertrophic chondrocytes reveal a mutation-specific unfolded protein response in chondrodysplasias
Pretemer, Y.; Kawai, S.; Watanabe, M.; Nagata, S.; Nishio, M.; Tamaki, S.; Alev, C.; Yamanaka, Y.; Xue, J.-Y.; Wang, Z.; Fukiage, K.; Tsukanaka, M.; Futami, T.; Ikegawa, S.; Toguchida, J.
10.1101/2020.05.19.103960 — cell biology — Posted on 2020-05-19
2124 Expanding Biomaterial Surface Topographical Design Space through Natural Surface Reproduction
de Boer, J.; Vermeulen, S.; Honig, F.; Vasilevich, A.; Roumans, N.; Carlier, A.; Romero, M.; Williams, P.; Uquillas, J. A.
10.1101/2020.05.18.099663 — cell biology — Posted on 2020-05-19
2129 Adenine Nucleotide Translocase regulates the airway epithelium, mitochondrial metabolism and ciliary function
Kliment, C.; Nguyen, J. M. K.; Kaltreider, M. J.; Lu, Y.-W.; Claypool, S. M.; Radder, J. E.; Sciurba, F. C.; Zhang, Y.; Gregory, A. D.; Iglesias, P. A.; Sidhaye, V. K.; Robinson, D. N.
10.1101/2020.05.18.101378 — cell biology — Posted on 2020-05-19
2131 Lipid Droplet Is an Ancient and Inheritable Organelle in Bacteria
Chi, X.; Ogunsade, O. O.; Zhou, Z.; Li, Z.; Li, X.; Zhang, M.; Song, F.; Wang, J.; Hammad, M. A.; Zhang, X.; Zhang, S.; Wan, X.; Zhang, L.; Zhang, C.; Liu, P.
10.1101/2020.05.18.103093 — cell biology — Posted on 2020-05-19
2135 Gut microbial metabolite p-Cresol promotes autistic-like behaviors in mice through remodeling of the microbiota
Bermudez-Martin, P.; Becker, J. J.; Fernandez, S. P.; Costa-Campos, R.; Barbosa, S.; Martinez Gili, L.; Myridakis, A.; Dumas, M. E.; Bruneau, A.; Cherbuy, C.; Langella, P.; Chabry, J.; Barik, J.; Le Merrer, J.; Glaichenhaus, N.; Davidovic, L.
10.1101/2020.05.18.101147 — neuroscience — Posted on 2020-05-19
2136 Endocannabinoids and dopamine balance basal ganglia output
Gorodetski, L.; Loewenstern, Y.; Faynveitz, A.; Bar-Gad, I.; Blackwell, K. T.; Korngreen, A.
10.1101/2020.05.18.099341 — neuroscience — Posted on 2020-05-19
2145 Tractor: A framework allowing for improved inclusion of admixed individuals in large-scale association studies.
Atkinson, E. G.; Maihofer, A. X.; Kanai, M.; Martin, A. R.; Karczewski, K. J.; Santoro, M. L.; Ulirsch, J. C.; Kamatani, Y.; Okada, Y.; Finucane, H. K.; Koenen, K. C.; Nievergelt, C. M.; Daly, M. J.; Neale, B. M.
10.1101/2020.05.17.100727 — genomics — Posted on 2020-05-19
2147 Temporal Changes Guided by Mesenchymal Stem Cells on a 3D Microgel Platform Enhances Angiogenesis In Vivo at a Low-Cell Dose
Thomas, D.; Marsico, G.; Mohd Isa, I. L.; Thirumaran, A.; Chen, X.; Lukasz, B.; Fontana, G.; Rodriguez, B.; Marchetti-Deschmann, M.; O'Brien, T.; Pandit, A.
10.1101/2020.05.16.086298 — bioengineering — Posted on 2020-05-19
2148 Thiazoline-related TRPA1 agonist odorants orchestrate survival fate in mice
Matsuo, T.; Isosaka, T.; Tang, L.; Soga, T.; Kobayakawa, R.; Kobayakawa, K.
10.1101/2020.05.17.100933 — physiology — Posted on 2020-05-19
2149 Comprehensive analyses of the cysteine thiol oxidation of PKM2 reveals the effects of multiple oxidation on cellular oxidative stress response
Irokawa, H.; Numasaki, S.; Kato, S.; Iwai, K.; Inose-Maruyama, A.; Ohadate, T.; Hwang, G.-W.; Toyama, T.; Watanabe, T.; Kuge, S.
10.1101/2020.05.14.097139 — molecular biology — Posted on 2020-05-19
2150 Plasmodium falciparum sexual parasites regulate infected erythrocyte permeability
Bouyer, G.; Barbieri, D.; Dupuy, F.; Marteau, A.; Sissoko, A.; N'Dri, M.-E.; Neveu, G.; Bedault, L.; Khodabux, N.; Roman, D.; Houze, S.; Siciliano, G.; Alano, P.; Martins, R. M.; Lopez-Rubio, J.-J.; Clain, J.; Duval, R.; Egee, S.; Lavazec, C.
10.1101/2020.05.18.101576 — microbiology — Posted on 2020-05-19
2153 Magnesium maintains length of circadian period in Arabidopsis thaliana
de Melo, J. R.; Gutsch, A.; De Caluwe, J.; Leloup, J.-C.; Gonze, D.; Hermans, C. R.; Webb, A. A.; Verbruggen, N.
10.1101/2020.05.14.096537 — molecular biology — Posted on 2020-05-19
2162 The specificity of SRC Homology 3 (SH3) domain interactions is modulated by their protein context in vivo
Dionne, U.; Bourgault, E.; Dube, A. K.; Bradley, D.; Chartier, F.; Dandage, R.; Dibyachintan, S.; Despres, P. C.; Gish, G. D.; Lambert, J.-P.; Bisson, N.; Landry, C. R.
10.1101/2020.05.18.103002 — systems biology — Posted on 2020-05-19
2164 Global Root Traits (GRooT) Database
Guerrero-Ramirez, N. R.; Mommer, L.; Freschet, G. T.; Iversen, C. M.; McCormack, M. L.; Kattge, J.; Poorter, H.; van der Plas, F.; Bergmann, J.; Kuyper, T. W.; York, L. M.; Bruelheide, H.; Laughlin, D. C.; Meier, I. C.; Roumet, C.; Semchenko, M.; Sweeney, C. J.; van Ruijven, J.; Valverde-Barrantes, O. J.; Aubin, I.; Catford, J. A.; Manning, P.; Martin, A. R.; Milla, R.; Minden, V.; Pausas, J. G.; Smith, S. W.; Soudzilovskaia, N. A.; Ammer, C.; Butterfield, B.; Craine, J.; Cornelissen, J. H. C.; de Vries, F. T.; Isaac, M. E.; Kramer, K.; König, C.; Lamb, E. G.; Onipchenko, V. G.; Penuelas, J.;
10.1101/2020.05.17.095851 — ecology — Posted on 2020-05-19
2165 Sierra: discovery of differential transcript usage from polyA-captured single-cell RNA-seq data
Patrick, R.; Humphreys, D. T.; Janbandhu, V.; Oshlack, A.; Ho, J. W. K.; Harvey, R. P.; Lo, K. K.
10.1101/867309 — bioinformatics — Posted on 2020-05-19
2166 Growth factor receptor signaling inhibition prevents SARS-CoV-2 replication
Klann, K.; Bojkova, D.; Tascher, G.; Ciesek, S.; Muench, C.; Cinatl, J.
10.1101/2020.05.14.095661 — systems biology — Posted on 2020-05-19
2167 RNAseq studies reveal distinct transcriptional response to vitamin A deficiency in small intestine versus colon, uncovering novel vitamin A-regulated genes
Chai, Z.; Lyu, Y.; Chen, Q.; Wei, C.-H.; Snyder, L. M.; Weaver, V.; Sebastian, A.; Albert, I.; Li, Q.; Cantorna, M.; Ross, C.
10.1101/798504 — physiology — Posted on 2020-05-19
2169 Characterization of miRNAs encoded by Autographa californica nucleopolyhedrovirus
Wang, J.; Xing, K.; Xiong, P.; Liang, H.; Zhu, M.; Huang, S.; Zhao, J.; Yu, X.; Ning, X.; Li, R.; Wang, X.
10.1101/2020.05.13.094193 — microbiology — Posted on 2020-05-19
2172 BitEpi: A Fast and Accurate Exhaustive Higher-Order Epistasis Search
Bayat, A.; Hosking, B.; Jain, Y.; Hosking, C.; Reti, D.; Twine, N.; C. Bauer, D.
10.1101/858282 — bioinformatics — Posted on 2020-05-19
2173 Resource availability and disturbance shape maximum tree height across the Amazon
Gorgens, E. B.; Nunes, M. H.; Jackson, T.; Coomes, D.; Keller, M.; Reis, C. R.; Valbuena, R.; Rosette, J.; Almeida, D. R. A.; Gimenez, B.; Cantinho, R. Z.; Motta, A. Z.; Assis, M.; Pereira, F. R. d. S.; Spanner, G.; Higuchi, N.; Ometto, J. P.
10.1101/2020.05.15.097683 — ecology — Posted on 2020-05-19
2174 Stress-induced translation inhibition through rapid displacement of scanning initiation factors
Bresson, S.; Shchepachev, V.; Spanos, C.; Turowski, T.; Rappsilber, J.; Tollervey, D.
10.1101/2020.05.14.096354 — cell biology — Posted on 2020-05-19
2179 Asymmetric transcallosal conduction delay leads to finer bimanual coordination
Bortoletto, M.; Bonzano, L.; Zazio, A.; Ferrari, C.; Pedulla, L.; Gasparotti, R.; Miniussi, C.; Bove, M.
10.1101/2020.01.24.918102 — neuroscience — Posted on 2020-05-19
2181 High-Resolution Linkage Map and QTL Analyses for Machine Harvest Traits in Autotetraploid Blueberry
Cappai, F.; Amadeu, R. R.; Benevenuto, J.; Cullen, R.; Garcia, A. L.; Grossman, A.; Ferrao, L. F. V.; Munoz, P. R.
10.1101/2020.05.13.093633 — genomics — Posted on 2020-05-19
2184 Cyrius: accurate CYP2D6 genotyping using whole genome sequencing data
Chen, X.; Shen, F.; Gonzaludo, N.; Malhotra, A.; Rogert, C.; Taft, R. J.; Bentley, D. R.; Eberle, M. A.
10.1101/2020.05.05.077966 — bioinformatics — Posted on 2020-05-19
2186 An anti-amyloidogenic treatment to specifically block the consolidation of traumatic events in mouse
Lopez-Garcia, P.; Ramirez de Mingo, D.; McGreevy, K. R.; Palle Lopez, A.; Popiel, H. A.; Santi, A.; Nagai, Y.; Trejo, J. L.; Carrion-Vazquez, M.
10.1101/2020.01.21.913053 — animal behavior and cognition — Posted on 2020-05-19
2187 Combined Effects of Standing and Passive Heating on Attenuating Sitting-Induced Vascular Dysfunction
Caldwell, A. R.; Jansen, L. T.; Rosa-Caldwell, M. E.; Howie, E. K.; Gallagher, K. M.; Turner, R. C.; Ganio, M. S.
10.1101/2020.04.30.060087 — physiology — Posted on 2020-05-19
2188 Persistent Epigenetic Reprogramming of Sweet Tase by Diet
Vaziri, A.; Khabiri, M.; Genaw, B. T.; May, C. E.; Freddolino, P.; Dus, M.
10.1101/2020.03.25.007773 — neuroscience — Posted on 2020-05-19
2189 Expert programmers have fine-tuned cortical representations of source code
Ikutani, Y.; Kubo, T.; Nishida, S.; Hata, H.; Matsumoto, K.; Ikeda, K.; Nishimoto, S.
10.1101/2020.01.28.923953 — neuroscience — Posted on 2020-05-19
2195 Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys
Nagai, Y.; Miyakawa, N.; Takuwa, H.; Hori, Y.; Oyama, K.; Ji, B.; Takahashi, M.; Huang, X.-P.; Slocum, S.; DiBerto, J. F.; Xiong, Y.; Urushihata, T.; Hirabayashi, T.; Fujimoto, A.; Mimura, K.; English, J. G.; Liu, J.; Inoue, K.-i.; Kumata, K.; Seki, C.; Ono, M.; Shimojo, M.; Zhang, M.-R.; Tomita, Y.; Nakahara, J.; Suhara, T.; Takada, M.; Higuchi, M.; Jin, J.; Roth, B. L.; Minamimoto, T.
10.1101/854513 — neuroscience — Posted on 2020-05-19
2203 Bacteria primed by antimicrobial peptides develop tolerance and persist
Rodriguez Rojas, A.; Baeder, D. Y.; Johnston, P. R.; Regoes, R. R.; Rolff, J.
10.1101/802207 — evolutionary biology — Posted on 2020-05-19
2205 Membrane-type 1 matrix metalloproteinase (MMP-14) modulates tissue homeostasis by a non-proteolytic mechanism
Attur, M. G.; Lu, C.; Zhang, X.; Han, T.; Alexandre, C.; Valacca, C.; Zheng, S.; Meikle, S.; Brukner Dabovic, B.; Tassone, E.; Yang, Q.; Kolupaeva, V.; Yakar, S.; Abramson, S. B.; Mignatti, P.
10.1101/631739 — cell biology — Posted on 2020-05-19
2207 Frontoparietal connectivity correlates with working memory performance in multiple sclerosis
Figueroa-Vargas, A.; Carcamo, C.; Henriquez-Ch., R. A.; Zamorano, F.; Ciampi, E.; Uribe, R.; Macarena, V.; Aboitiz, F.; Billeke, P.
10.1101/639930 — neuroscience — Posted on 2020-05-19
2208 Brain structures associated with reading and their abnormalities in dyslexia: a whole-brainanalysis
Kujala, T.; Thiede, A.; Palo-oja, P.; Virtala, P.; Laasonen, M.; Numminen, J.; Sihvonen, A. J.
10.1101/2020.03.27.011577 — neuroscience — Posted on 2020-05-19
2209 GIGYF2 and 4EHP Inhibit Translation Initiation of Defective Messenger RNAs to Assist Ribosome-Associated Quality Control
Hickey, K. L.; Dickson, K.; Cogan, J. Z.; Replogle, J. M.; Schoof, M.; D'Orazio, K. N.; Sinha, N. K.; Frost, A.; Green, R.; Kostova, K. K.; Weissman, J. S.
10.1101/792994 — genetics — Posted on 2020-05-19
2210 EMT-induced cell mechanical changes enhance mitotic rounding strength
Hosseini, K.; Taubenberger, A.; Werner, C.; Fischer-Friedrich, E.
10.1101/598052 — biophysics — Posted on 2020-05-19
2213 Th2-like T-follicular helper cells promote functional antibody production during Plasmodium falciparum infection
Chan, J.-A.; de Labastida Rivera, F.; Loughland, J.; Engel, J. A.; Lee, H. J.; SheelaNair, A.; Wines, B.; Amante, F.; Webb, L.; Mukhopadhyay, P.; Patch, A.-M.; Hogarth, M.; Beeson, J. A.; McCarthy, J.; Haque, A.; Engwerda, C.; Boyle, M. J.
10.1101/2020.05.18.101048 — immunology — Posted on 2020-05-19
2214 Integrated multi-omics reveals common properties underlying stress granule and P-body formation
Kershaw, C.; Nelson, M. G.; Lui, J.; Bates, C. P.; Jennings, M. D.; Hubbard, S. J.; Ashe, M. P.; Grant, C. M.
10.1101/2020.05.18.102517 — biochemistry — Posted on 2020-05-19
2215 Suppression of liquid-liquid phase separation by 1,6-hexanediol partially compromises the 3D genome organization in living cells
Ulianov, S. V.; Velichko, A. K.; Magnitov, M. D.; Luzhin, A. V.; Golov, A. K.; Ovsyannikova, N.; Kireev, I. I.; Tyakht, A. V.; Gavrilov, A. A.; Kantidze, O. L.; Razin, S. V.
10.1101/2020.05.18.101261 — molecular biology — Posted on 2020-05-19
2216 Histone deposition pathways determine the chromatin landscapes of H3.1 and H3.3 K27M oncohistones
Sarthy, J. F.; Meers, M. P.; Janssens, D.; Henikoff, J. G.; Morris, S.; Biery, M.; Feldman, H.; Paddison, P. J.; Vitanza, N.; Olson, J. M.; Ahmad, K.; Henikoff, S.
10.1101/2020.05.18.101709 — molecular biology — Posted on 2020-05-19
2217 Downregulation of E-cadherin in pluripotent stem cells triggers partial EMT
Aban, C.; Lombardi, A.; Neiman, G.; Biani, M. C.; La Greca, A.; Waisman, A.; Moro, L. N.; Sevlever, G. E.; Miriuka, S. G.; Luzzani, C.
10.1101/2020.05.18.101899 — cell biology — Posted on 2020-05-19
2218 SDE2 Integrates into the TIMELESS-TIPIN Complex to Protect Stalled Replication Forks
Rageul, J.; Park, J.; Zeng, P. P.; Lee, E.-A.; Yang, J.; Hwang, S.; Lo, N.; Weinheimer, A.; Scharer, O.; Yeo, J.-E.; Kim, H.
10.1101/2020.05.18.097154 — cell biology — Posted on 2020-05-18
2219 Age-related changes in the motor planning strategy slow down motor initiation in elderly adults
Frolov, N. S.; Pitsik, E. N.; Maksimenko, V. A.; Grubov, V. V.; Kiselev, A. R.; Wang, Z.; Hramov, A. E.
10.1101/2020.05.18.101774 — neuroscience — Posted on 2020-05-18
2220 Single caudate neurons encode temporally discounted value for formulating motivation for action
Hori, Y.; Mimura, K.; Nagai, Y.; Fujimoto, A.; Oyama, K.; Kikuchi, E.; Inoue, K.-i.; Takada, M.; Suhara, T.; Richmond, B. J.; Minamimoto, T.
10.1101/2020.05.18.101824 — neuroscience — Posted on 2020-05-18
2221 Learning receptive field properties of complex cells in V1
Lian, Y.; Almasi, A.; Grayden, D. B.; Kameneva, T.; Burkitt, A. N.; Meffin, H.
10.1101/2020.05.18.101873 — neuroscience — Posted on 2020-05-18
2222 Learning receptive field properties of complex cells in V1
Lian, Y.; Almasi, A.; Grayden, D. B.; Kameneva, T.; Burkitt, A. N.; Meffin, H.
10.1101/2020.05.18.101881 — neuroscience — Posted on 2020-05-18
2223 Repurposing of Miglustat to inhibit the coronavirus Severe Acquired Respiratory Syndrome SARS-CoV-2
Rajasekharan, S.; Milan Bonotto, R.; Kazungu, Y.; Nascimento Alves, L.; Poggianella, M.; Martinez Orellana, P.; Skoko, N.; Polez, S.; Marcello, A.
10.1101/2020.05.18.101691 — microbiology — Posted on 2020-05-18
2225 Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2.
Case, J. B.; Rothlauf, P. W.; Chen, R. E.; Liu, Z.; Zhao, H.; Kim, A. S.; Bloyet, L.-M.; Zeng, Q.; Tahan, S.; Droit, L.; Ilagan, M. X. G.; Tartell, M. A.; Amarasinghe, G. K.; Henderson, J. P.; Miersch, S.; Ustav, M.; Sidhu, S.; Virgin, H. W.; Wang, D.; Ding, S.; Corti, D.; Theel, E. S.; Fremont, D. H.; Diamond, M. S.; Whelan, S. P. J.
10.1101/2020.05.18.102038 — microbiology — Posted on 2020-05-18
2227 SARS-CoV2 infection in farmed mink, Netherlands, April 2020
Oreshkova, N.; Molenaar, R.-J.; Vreman, S.; Harders, F.; Oude Munnink, B. B.; Hakze-vd Honing, R. W.; Gerhards, N.; Tolsma, P.; Bouwstra, R.; Sikkema, R.; Tacken, M.; de Rooij, M. M. T.; Weesendorp, E.; Engelsma, M.; Bruschke, C.; Smit, L. A. M.; Koopmans, M.; van der Poel, W. H. M.; Stegeman, J.
10.1101/2020.05.18.101493 — microbiology — Posted on 2020-05-18
2228 Immunologic perturbations in severe COVID-19/SARS-CoV-2 infection
Kuri-Cervantes, L.; Pampena, M. B.; Meng, W.; Rosenfeld, A. M.; Ittner, C. A. G.; Weisman, A. R.; Agyekum, R.; Mathew, D.; Baxter, A. E.; Vella, L.; Kuthuru, O.; Apostolidis, S.; Bershaw, L.; Dougherty, J.; Greenplate, A. R.; Pattekar, A.; Kim, J.; Han, N.; Gouma, S.; Weirick, M. E.; Arevalo, C. P.; Bolton, M. J.; Goodwin, E. C.; Anderson, E. M.; Hensley, S. E.; Jones, T. K.; Mangalmurti, N. S.; Luning Prak, E. T.; Meyer, N. J.; Kim, J.; Betts, M. R.
10.1101/2020.05.18.101717 — immunology — Posted on 2020-05-18
2229 Controlling the SARS-CoV-2 Spike Glycoprotein Conformation
Henderson, R.; Edwards, R. J.; Mansouri, K.; Janowska, K.; Stalls, V.; Gobeil, S.; Kopp, M.; Hsu, A. L.; Borgnia, M. J.; Parks, R.; Haynes, B. F.; Acharya, P.
10.1101/2020.05.18.102087 — immunology — Posted on 2020-05-18
2230 Longitudinal high-throughput TCR repertoire profiling reveals the dynamics of T cell memory formation after mild COVID-19 infection
Minervina, A. A.; Komech, E. A.; Titov, A.; Bensouda Koraichi, M.; Rosati, E.; Mamedov, I. Z.; Franke, A.; Efimov, G. A.; Chudakov, D. M.; Mora, T.; Walczak, A. M.; Lebedev, Y. B.; Pogorelyy, M. V.
10.1101/2020.05.18.100545 — immunology — Posted on 2020-05-18
2231 Does the human placenta express the canonical cell entry mediators for SARS-CoV-2?
Pique-Regi, R.; Romero, R.; Tarca, A. L.; Luca, F.; Xu, Y.; Leng, Y.; Hsu, C.-D.; Gomez-Lopez, N.
10.1101/2020.05.18.101485 — genomics — Posted on 2020-05-18
2232 Afucosylated immunoglobulin G responses are a hallmark of enveloped virus infections and show an exacerbated phenotype in COVID-19
Larsen, M. D.; de Graaf, E. L.; Sonneveld, M. E.; Plomp, H. R.; Linty, F.; Visser, R.; Brinkhaus, M.; Sustic, T.; deTaeye, S. W.; Bentlage, A. E. H.; Nouta, J.; Natunen, S.; Koeleman, C. A. M.; Sainio, S.; Kootstra, N. A.; Brouwer, P. J. M.; Sanders, R. W.; van Gils, M. J.; de Bruin, S.; Vlaar, A. P. J.; Amsterdam UMC COVID-19 biobank study group, ; Zaaijer, H. L.; Wuhrer, M.; van der Schoot, C. E.; Vidarsson, G.
10.1101/2020.05.18.099507 — immunology — Posted on 2020-05-18
2236 Molecular mapping of qBK1Z, a major QTL for bakanae disease resistance in rice
Lee, S.-B.; Kim, N.; Jo, S.; Hur, Y.-J.; Cho, J.-H.; Lee, J.-y.; Lee, J.-H.; Song, Y.-C.; Ko, J.-M.; Seo, Y.-S.; Lee, J.; Bombay, M.; Kim, S.-R.; Park, D.-S.
10.1101/2020.05.18.101725 — plant biology — Posted on 2020-05-18
2237 Glycosaminoglycans are specific endosomal receptors for Yersinia pseudotuberculosis Cytotoxic Necrotizing Factor
Schmidt, G.; Kowarschik, S.; Schöllkopf, J.; Mueller, T.; Tian, S.; Knerr, J.; Bakker, H.; Rein, S.; Dong, M.; Weber, S.; Grosse, R.
10.1101/2020.05.18.101790 — pharmacology and toxicology — Posted on 2020-05-18
2238 Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2
Thoms, M.; Buschauer, R.; Ameismeier, M.; Koepke, L.; Denk, T.; Hirschenberger, M.; Kratzat, H.; Hayn, M.; Mackens-Kiani, T.; Cheng, J.; Stuerzel, C. M.; Froehlich, T.; Berninghausen, O.; Becker, T.; Kirchhoff, F.; Sparrer, K. M. J.; Beckmann, R.
10.1101/2020.05.18.102467 — molecular biology — Posted on 2020-05-18
2240 Leptospiral LPS escapes mouse TLR4 internalization and TRIF?associated antimicrobial responses through O antigen and associated lipoproteins
Bonhomme, D.; Santecchia, I.; Vernel-Pauillac, F.; Caroff, M.; Germon, P.; Murray, G.; Adler, B.; Boneca, I. G.; Werts, C.
10.1101/2020.05.18.101857 — immunology — Posted on 2020-05-18
2241 Deviation from mendelian transmission of autosomal SNPs can be used to estimate germline mutations in humans exposed to ionizing radiation
Leite Filho, H. P.; Pinto, I. P.; Oliveira, L. G.; Costa, E. O. A.; da Cruz, A. S.; e Silva, D. d. M.; da Silva, C. C.; Caetano, A. R.; da Cruz, A. D.
10.1101/2020.05.18.101816 — genetics — Posted on 2020-05-18
2242 Highly sensitive and full-genome interrogation of SARS-CoV-2 using multiplexed PCR enrichment followed by next-generation sequencing
Li, C.; Debruyne, D. N.; Spencer, J.; Kapoor, V.; Liu, L. Y.; Zhou, B.; Pandey, U.; Bootwalla, M.; Ostrow, D.; Maglinte, D. T.; Ruble, D.; Ryutov, A.; Shen, L.; Lee, L.; Feigelman, R.; Burdon, G.; Liu, J.; Oliva, A.; Borcherding, A.; Tan, H.; Urban, A. E.; Gai, X.; Bard, J. D.; Liu, G.; Liu, Z.
10.1101/2020.03.12.988246 — genomics — Posted on 2020-05-18
2243 Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia
Brann, D.; Tsukahara, T.; Weinreb, C.; Lipovsek, M.; Van den Berge, K.; Gong, B.; Chance, R.; Macaulay, I. C.; Chou, H.-j.; Fletcher, R.; Das, D.; Street, K.; Roux de Bezieux, H.; Choi, Y.-G.; Risso, D.; Dudoit, S.; Purdom, E.; Mill, J. C.; Hachem, R. A.; Matsunami, H.; Logan, D. W.; Goldstein, B.; Grubb, M. S.; Ngai, J.; Datta, S. R.
10.1101/2020.03.25.009084 — neuroscience — Posted on 2020-05-18
2244 T cells expanded from renal cell carcinoma are tumor-reactive but fail to produce IFN-γ, TNF-α or IL-2
van Asten, S. D.; Groot, R. d.; van Loenen, M. M.; Jong, J. d.; Monkhorst, K.; Haanen, J. B.; Amsen, D.; Bex, A.; Spaapen, R. M.; Wolkers, M. C.
10.1101/2020.05.17.098558 — immunology — Posted on 2020-05-18
2245 Chromosome scale reference genome of Cluster bean (Cyamopsis tetragonoloba (L.) Taub.)
Gaikwad, K.; Ramakrishna, G.; Srivastava, H.; Saxena, S.; Kaila, T.; Tyagi, A.; Sharma, P.; Sharma, S.; Sharma, R.; Mahla, H.; SV, A. M.; Solanke, A.; Kalia, P.; Rao, A.; Rai, A.; Sharma, T.; Singh, N.
10.1101/2020.05.16.098434 — genomics — Posted on 2020-05-18
2246 A novel fragmented mitochondrial genome in the protist pathogen Toxoplasma gondii and related tissue coccidia
Namasivayam, S.; Baptista, R. d. P.; Xiao, W.; Hall, E. M.; Doggett, J. S.; Troell, K.; Kissinger, J. C.
10.1101/2020.05.16.099366 — genomics — Posted on 2020-05-18
2250 Diazotrophic bacteria from maize exhibit multifaceted plant growth promotion traits in multiple hosts
Higdon, S. M.; Pozzo, T.; Tibbitt, E.; Chiu, C.; Jeannotte, R.; Bennett, A. B.; Weimer, B. C.
10.1101/2020.05.17.100859 — microbiology — Posted on 2020-05-17
2254 Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenes
Brouwer, S.; Barnett, T. C.; Ly, D.; Kasper, K. J.; De Oliveira, D. M.; Rivera-Hernandez, T.; Cork, A. J.; McIntyre, L.; Jespersen, M. G.; Richter, J.; Schulz, B. L.; Dougan, G.; Nizet, V.; Yuen, K.-Y.; You, Y.; McCormick, J. K.; Sanderson-Smith, M. L.; Davies, M. R.; Walker, M. J.
10.1101/2020.05.17.095000 — microbiology — Posted on 2020-05-17
2256 Potent programmable antiviral against dengue virus in primary human cells by Cas13b RNP with short spacer and delivery by virus-like particle
Singsuksawat, E.; Onnome, S.; Posiri, P.; Suphatrakul, A.; Srisuk, N.; Nantachokchawapan, R.; Praneechit, H.; Sae-kow, C.; Chidpratum, P.; Hongeng, S.; Avirutnan, P.; Duangjinda, T.; Siridechadilok, B.
10.1101/2020.05.17.100388 — microbiology — Posted on 2020-05-17
2258 The naked cell: emerging properties of a surfome-streamlined Pseudomonas putida strain
Martinez-Garcia, E.; Fraile, S.; Rodriguez-Espeso, D.; Vecchietti, D.; Bertoni, G.; de Lorenzo, V.
10.1101/2020.05.17.100628 — synthetic biology — Posted on 2020-05-17
2259 Modern Machine Learning: Partition & Vote
Priebe, C. E.; Vogelstein, J.; Engert, F.; White, C. M.
10.1101/2020.04.29.068460 — neuroscience — Posted on 2020-05-17
2261 Massively parallel assessment of human variants with base editor screens
Hanna, R. E.; Hegde, M.; Fagre, C. R.; DeWeirdt, P. C.; Sangree, A. K.; Szegletes, Z.; Griffith, A.; Feeley, M. N.; Sanson, K. R.; Baidi, Y.; Koblan, L. W.; Liu, D. R.; Neal, J. T.; Doench, J. G.
10.1101/2020.05.17.100818 — genetics — Posted on 2020-05-17
2266 Advancing Divide-and-Conquer Phylogeny Estimation
Yu, X.; Le, T.; Christensen, S.; Molloy, E. K.; Warnow, T.
10.1101/2020.05.16.099895 — bioinformatics — Posted on 2020-05-17
2269 A novel platform to accelerate antimicrobial susceptibility testing in Neisseria gonorrhoeae using RNA signatures
M.Hashemi, M.; Ram-Mohan, N.; Yang, X.; Andini, N.; Gessner, N. R.; Carroll, K. C.; Wang, T.-H.; Yang, S.
10.1101/2020.05.05.078808 — molecular biology — Posted on 2020-05-17
2271 Community-scale Synchronization and Temporal Partitioning of Gene Expression, Metabolism, and Lipid Biosynthesis in Oligotrophic Ocean Surface Waters
Muratore, D.; Boysen, A. K.; Harke, M. J.; Becker, K. W.; Casey, J. R.; Coesel, S. N.; Mende, D. R.; Wilson, S. T.; Aylward, F. O.; Eppley, J. M.; Vislova, A.; Peng, S.; Rodriguez-Gonzalez, R. A.; Beckett, S. J.; Armbrust, E. V.; DeLong, E. F.; Karl, D. M.; White, A. E.; Zehr, J. P.; Van Mooy, B. A. S.; Dyhrman, S. T.; Ingalls, A. E.; Weitz, J. S.
10.1101/2020.05.15.098020 — ecology — Posted on 2020-05-17
2272 Ebselen as a highly active inhibitor of PLProCoV2
Weglarz-Tomczak, E.; Tomczak, J. M.; Talma, M.; Brul, S.
10.1101/2020.05.17.100768 — biochemistry — Posted on 2020-05-17
2273 Hypoxia-Sensing CAR T-Cells Provide Safety and Efficacy in Treating Solid Tumors
Kosti, P.; Opzoomer, J.; Larios Martinez, K.; Henley-Smith, R.; Scudamore, C.; Okesola, M.; Taher, M.; Davies, D.; Muliaditan, T.; Larcombe-Young, D.; Woodman, N.; Gillett, C.; Thavaraj, S.; Maher, J.; Arnold, J.
10.1101/2020.05.13.091546 — synthetic biology — Posted on 2020-05-17
2276 Saturation of influenza virus neutralization and antibody consumption can both lead to bistable growth kinetics
Xu, S.; Yan, A. W. C.; Peck, H.; Gillespie, L.; Barr, I. G.; Yang, X.; Turner, S. J.; Donato, C. M.; Zhang, T.; Olshansky, M.; Dhanasekaran, V.
10.1101/2020.03.02.973958 — microbiology — Posted on 2020-05-17
2279 DYNAMICS OF CLONAL HEMATOPOIESIS IN A SUPER-CENTENARIAN
van den Akker, E. B.; Makrodimitris, S.; Hulsman, M.; Brugman, M. H.; Nikolic, T.; Bradley, T.; Waisfisz, Q.; Baas, F.; Jakobs, M. E.; de Jong, D.; Slagboom, P. E.; Staal, F. J.; Reinders, M. J.; Holstege, H.
10.1101/788752 — immunology — Posted on 2020-05-17
2281 Optogenetic therapy: High spatiotemporal resolution and pattern recognition compatible with vision restoration in non-human primates
Gauvain, G.; Akolkar, H.; Chaffiol, A.; Arcizet, F.; Khoei, M.; Desrosiers, M.; Jaillard, C.; Caplette, R.; Marre, O.; Bertin, S.; Fovet, C.-M.; Demilly, J.; Forster, V.; Brazhnikova, E.; Hantraye, P.; Pouget, P.; Douar, A.; Pruneau, D.; Chavas, J.; Sahel, J.-A.; Dalkara, D.; Duebel, J.; Benosman, R.; Picaud, S.
10.1101/2020.05.17.100230 — neuroscience — Posted on 2020-05-17
2283 Distinct conformational states of SARS-CoV-2 spike protein
Cai, Y.; Zhang, J.; Xiao, T.; Peng, H.; Sterling, S. M.; Walsh, R. M.; Rawson, S.; Rits-Volloch, S.; Chen, B.
10.1101/2020.05.16.099317 — biochemistry — Posted on 2020-05-17
2285 Establishment of an African green monkey model for COVID-19
Woolsey, C. B.; Borisevich, V.; Prasad, A. N.; Agans, K. N.; Deer, D. J.; Dobias, N. S.; Heymann, J. C.; Foster, S. L.; Levine, C. B.; Medina, L.; Melody, K.; Geisbert, J. B.; Fenton, K. A.; Geisbert, T. W.; Cross, R. W.
10.1101/2020.05.17.100289 — microbiology — Posted on 2020-05-17
2287 Epitope-Based Peptide Vaccine Against Severe Acute Respiratory Syndrome-Coronavirus-2 Nucleocapsid Protein: An in silico Approach
Rakib, A.; Sami, S. A.; Islam, M. A.; Ahmed, S.; Faiz, F. B.; Khanam, B. H.; Uddin, M. M. N.; Emran, D. T. B.
10.1101/2020.05.16.100206 — bioinformatics — Posted on 2020-05-17
2288 Binding of the SARS-CoV-2 Spike Protein to Glycans
Hao, W.; Ma, B.; Li, Z.; Wang, X.; Gao, X.; Li, Y.; Qin, B.; Shang, S.; Cui, S.; Tan, Z.
10.1101/2020.05.17.100537 — biochemistry — Posted on 2020-05-17
2291 The Host Cell ViroCheckpoint: Identification and Pharmacologic Targeting of Novel Mechanistic Determinants of Coronavirus-Mediated Hijacked Cell States
Laise, P.; Bosker, G.; Sun, X.; Shen, Y.; Douglass, E. F.; Karan, C.; Realubit, R. B.; Pampou, S.; Califano, A.; Alvarez, M. J.
10.1101/2020.05.12.091256 — systems biology — Posted on 2020-05-17
2295 Modulation of endothelial organelle size as an antithrombotic strategy
Ferraro, F.; Rodrigues Simoes Da Costa, J.; Kriston-Vizi, J.; Ketteler, R.; Cutler, D. F.
10.1101/2020.05.16.099580 — cell biology — Posted on 2020-05-17
2296 Tracking Single Particles for Hours via Continuous DNA-mediated Fluorophore Exchange
Stehr, F.; Stein, J.; Bauer, J.; Niederauer, C.; Jungmann, R.; Ganzinger, K. A.; Schwille, P.
10.1101/2020.05.17.100354 — biophysics — Posted on 2020-05-17
2297 Mapping Cell Membrane Organization and Dynamics Using Soft Nano-Imprint Lithography
Sansen, T.; Sanchez-Fuentes, D.; Rathar, R.; Colom-Diego, A.; El Alaoui, F.; Viaud, J.; Macchione, M.; de Rossi, S.; Matile, S.; Gaudin, R.; Baeker, V.; Carretero-Genevrier, A.; Picas, L.
10.1101/767590 — biophysics — Posted on 2020-05-17
2299 Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis
Jungwirth, U.; van Weverwijk, A.; Jenkins, L.; Alexander, J.; Vicente, D.; Gao, Q.; Haider, S.; Iravani, M.; Isacke, C. M.
10.1101/2020.05.17.100412 — cancer biology — Posted on 2020-05-17
2302 Lipoic acid biosynthesis is essential for Plasmodium falciparum transmission and influences redox response and carbon metabolism of parasite asexual blood stages
Biddau, M.; Kumar, S. T. R.; Henrich, P.; Laine, L. M.; Blackburn, G. J.; Chokkathukalam, A.; Li, T. B.; Sim, K. L.; Hoffman, S. L.; Barrett, M. P.; Coombs, G. H.; McFadden, G. I.; Fidock, D. A.; Muller, S.; Sheiner, L.
10.1101/2020.05.17.099630 — cell biology — Posted on 2020-05-17
2305 Validity of the Lumen(R) hand-held metabolic device to measure fuel utilization in healthy young adults
Lorenz, K. A.; Yeshurun, S.; Aziz, R.; Ortiz-Delatorre, J.; Bagley, J. R.; Mor, M.; Kern, M.
10.1101/2020.05.05.078980 — physiology — Posted on 2020-05-17
2307 MINPP1 prevents intracellular accumulation of the cation chelator inositol hexakisphosphate and is mutated in Pontocerebellar Hypoplasia
Ucuncu, E.; Rajamani, K.; Wilson, M. S. C.; Medina-Cano, D.; Altin, N.; David, P.; Barcia, G.; Lefort, N.; Vasilache-Dangles, M.-T.; Pitelet, G.; Lorino, E.; Rabasse, N.; Bieth, E.; Zaki, M. S.; Topcu, M.; Sonmez, F. M.; Musaev, D.; Stanley, V.; Bole-Feysot, C.; Nitschke, P.; Munnich, A.; Bahi-Buisson, N.; Fossoud, C.; Giuliano, F.; Colleaux, L.; Burglen, L.; Gleeson, J. G.; Boddaert, N.; Saiardi, A.; Cantagrel, V.
10.1101/2020.05.17.100248 — genetics — Posted on 2020-05-17
2311 The serogroup B meningococcal outer membrane vesicle-based vaccine 4CMenB induces cross-species protection against Neisseria gonorrhoeae
Leduc, I.; Connolly, K. L.; Begum, A.; Underwood, K.; Rahman, N.; Darnell, s.; Balthazar, J.; shafer, w.; Macintyre, A. N.; sempowski, g.; Jerse, A.
10.1101/2020.05.13.094177 — microbiology — Posted on 2020-05-17
2315 A rat epigenetic clock recapitulates phenotypic aging and co-localizes with heterochromatin-associated histone modifications
Levine, M.; McDevitt, R.; Meer, M.; Perdue, K.; Di Francesco, A.; Meade, T.; Farrell, C.; Thrush, K.; Wang, M.; Dunn, C.; Pellegrini, M.; deCabo, R.; Ferrucci, L.
10.1101/2020.05.13.094292 — molecular biology — Posted on 2020-05-17
2316 Preventive efficacy of a tenofovir alafenamide fumarate nanofluidic implant in SHIV-challenged nonhuman primates
Pons-Faudoa, F. P.; Sizovs, A.; Shelton, K. A.; Momin, Z.; Bushman, L. R.; Chua, C. Y. X.; Nichols, J. E.; Hawkins, T.; Rooney, J. F.; Marzinke, M. A.; Kimata, J. T.; Anderson, P. L.; Nehete, P. N.; Arduino, R. C.; Ferrari, M.; Sastry, K. J.; Grattoni, A.
10.1101/2020.05.13.091694 — bioengineering — Posted on 2020-05-17
2318 Altered kinetics of circulating progenitor cells in cardiopulmonary bypass (CPB) associated vasoplegic patients: An observational study
Nandi, S.; Kumari, C.; Potunuru, U. R.; Nathan, A. A.; Gopal, J.; Menon, G. I.; Siddharthan, R.; Dixit, M.; Thangaraj, P. R.
10.1101/2020.03.11.987099 — physiology — Posted on 2020-05-17
2322 NAIP-NLRC4-deficient mice are susceptible to shigellosis
Mitchell, P. S.; Roncaioli, J. L.; Turcotte, E. A.; Goers, L.; Chavez, R. A.; Lee, A. Y.; Lesser, C. F.; Rauch, I.; Vance, R. E.
10.1101/2020.05.16.099929 — microbiology — Posted on 2020-05-17
2323 Metagenomic identification of diverse animal hepaciviruses and pegiviruses
Porter, A. F.; Pettersson, J. H.- O.; Chang, W.-S.; Harvey, E.; Rose, K.; Shi, M.; Eden, J.-S.; Buchmann, J.; Moritz, C.; Holmes, E. C.
10.1101/2020.05.16.100149 — microbiology — Posted on 2020-05-17
2328 The low complexity motif of cytoplasmic polyadenylation element binding protein 3 (CPEB3) is critical for the trafficking of its targets in neurons
Ford, L.; Asok, A.; Tripp, A. D.; Parro, C.; Fitzpatrick, M.; de Solis, C. A.; Shafiian, N.; Fioriti, L.; Soni, R. K.; Kandel, E.
10.1101/2020.05.16.100032 — neuroscience — Posted on 2020-05-17
2334 Spatiotemporal variation in drivers of parasitism in a wild wood mouse population
Sweeny, A. R.; Albery, G. F.; Venkatesan, S.; Fenton, A.; Pedersen, A. B.
10.1101/2020.05.16.099481 — ecology — Posted on 2020-05-17
2337 Advancing Divide-and-Conquer Phylogeny Estimation
Yu, X.; Le, T.; Christensen, S.; Molloy, E. K.; Warnow, T.
10.1101/2020.05.16.099895 — bioinformatics — Posted on 2020-05-17
2338 Plasma metabolomics of presymptomatic PSEN1-H163Y mutation carriers: A pilot study
Natarajan, K.; Ullgren, A.; Khoshnood, B.; johansson, c.; Laffita, J.; Pannee, J.; Zetterberg, H.; Blennow, K.; Graff, C.
10.1101/2020.05.16.093559 — neuroscience — Posted on 2020-05-17
2339 Label-free optical detection of bioelectric potentials using electrochromic thin films
Alfonso, F. S.; Zhou, Y.; Liu, E.; McGuire, A. F.; Yang, Y.; Kantarci, H.; Li, D.; Copenhaver, E.; Zuchero, J. B.; Muller, H.; Cui, B.
10.1101/2020.05.16.099002 — neuroscience — Posted on 2020-05-17
2340 MutantHuntWGS: A Pipeline for Identifying Saccharomyces cerevisiae Mutations
Ellison, M. A.; Walker, J. L.; Ropp, P. J.; Durrant, J. D.; Arndt, K. M.
10.1101/2020.05.16.099259 — genetics — Posted on 2020-05-17
2345 A unique and evolutionarily conserved retinal interneuron relays rod and cone input to the inner plexiform layer
Young, B. K.; Ramakrishnan, C.; Ganjawala, T.; Li, Y.; Kim, S.; Wang, P.; Chen, R.; Deisseroth, K.; Tian, N.
10.1101/2020.05.16.100008 — neuroscience — Posted on 2020-05-17
2346 Altered oligodendroglia and astroglia in chronic traumatic encephalopathy
Chancellor, K. B.; Chancellor, S. E.; Duke-Cohan, J. E.; Huber, B. R.; Stein, T. D.; Alvarez, V. E.; McKee, A. C.
10.1101/2020.05.13.089086 — genomics — Posted on 2020-05-17
2348 An Atlas of Gene Regulatory Elements in Adult Mouse Cerebrum
Li, Y. E.; Preissl, S.; Hou, X.; Zhang, Z.; Zhang, K.; Fang, R.; Qiu, Y.; Poirion, O.; Li, B.; Yan, Y.; Liu, H.; Wang, X.; Han, J. Y.; Lucero, J.; Kuan, S.; Gorkin, D.; Nunn, M.; Mukamel, E. A.; Behrens, M. M.; Ecker, J. R.; Ren, B.
10.1101/2020.05.10.087585 — neuroscience — Posted on 2020-05-17
2350 A community-maintained standard library of population genetic models
Adrion, J. R.; Cole, C. B.; Dukler, N.; Galloway, J. G.; Gladstein, A. L.; Gower, G.; Kyriazis, C. C.; Ragsdale, A. P.; Tsambos, G.; Baumdicker, F.; Carlson, J.; Cartwright, R. A.; Durvasula, A.; Gronau, I.; Kim, B. Y.; McKenzie, P.; Messer, P. W.; Noskova, E.; Ortega-Del Vecchyo, D.; Racimo, F.; Struck, T. J.; Gravel, S.; Gutenkunst, R. N.; Lohmueller, K.; Ralph, P. L.; Schrider, D. R.; Siepel, A.; Kelleher, J.; Kern, A. D.
10.1101/2019.12.20.885129 — evolutionary biology — Posted on 2020-05-17
2351 Improved RAD51 binders through motif shuffling based on the modularity of BRC repeats
Lindenburg, L.; Pantelejevs, T.; Gielen, F.; Zuazua-Villar, P.; Butz, M.; Rees, E. J.; Kaminski, C. F.; Downs, J.; Hyvonen, M.; Hollfelder, F.
10.1101/2020.05.14.097071 — biochemistry — Posted on 2020-05-17
2352 Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein
Wec, A. Z.; Wrapp, D.; Herbert, A. S.; Maurer, D. P.; Haslwanter, D.; Sakharkar, M.; Jangra, R. K.; Dieterle, M. E.; Lilov, A.; Huang, D.; Tse, L. V.; Johnson, N. V.; Hsieh, C.-L.; Wang, N.; Nett, J. H.; Champney, E.; Burnina, I.; Brown, M.; Lin, S.; Sinclair, M.; Johnson, C.; Pudi, S.; Bortz, R.; Wirchnianski, A. S.; Laudermilch, E.; Florez, C.; Fels, J. M.; O'Brien, C. M.; Graham, B. S.; Nemazee, D.; Burton, D. R.; Baric, R. S.; Voss, J. E.; Chandran, K.; Dye, J. M.; McLellan, J. S.; Walker, L. M.
10.1101/2020.05.15.096511 — immunology — Posted on 2020-05-16
2355 Sybodies targeting the SARS-CoV-2 receptor-binding domain
Walter, J. D.; Hutter, C. A. J.; Zimmermann, I.; Wyss, M.; Egloff, P.; Sorgenfrei, M.; Hürlimann, L. M.; Gonda, I.; Meier, G.; Remm, S.; Thavarasah, S.; Plattet, P.; Seeger, M. A.
10.1101/2020.04.16.045419 — biochemistry — Posted on 2020-05-16
2360 Real-time suppression and amplification of frequency-specific neural activity using stimulation evoked oscillations
Escobar Sanabria, D.; Johnson, L. A.; Yu, Y.; Busby, Z.; Nebeck, S.; Zhang, J.; Harel, N.; Johnson, M. D.; Molnar, G. F.; Vitek, J. L.
10.1101/2020.02.09.940643 — neuroscience — Posted on 2020-05-16
2361 Clonal Heterogeneity Supports Mitochondrial Metabolism in Pancreatic Cancer
Halbrook, C. J.; Thurston, G.; McCarthy, A.; Nelson, B. S.; Sajjakulnukit, P.; Krall, A. S.; Mullen, P. J.; Zhang, L.; Batra, S.; Viale, A.; Stanger, B. Z.; Cristofk, H. R.; Zhang, J.; Pasca di Magliano, M.; Jorgensen, C.; Lyssiotis, C. A.
10.1101/2020.05.15.098368 — cancer biology — Posted on 2020-05-16
2362 Single cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype
Valdes-Mora, F.; Salomon, R.; Gloss, B. S.; Law, A. M.; Castillo, L.; Murphy, K.; Venhuizen, J.; Magenau, A.; Papanicolau, M.; Rodriguez de la Fuente, L.; Roden, D. L.; Colino-Sanguino, Y.; Kikhtyak, Z.; Farbehi, N.; Conway, J. R.; Oakes, S. R.; Sikta, N.; O'Donoghue, S.; Cox, T. R.; Timpson, P.; Ormandy, C. J.; Gallego-Ortega, D.
10.1101/624890 — cancer biology — Posted on 2020-05-16
2363 Dual Role of a Rubisco Activase in Metabolic Repair and Carboxysome Organization
Hayer-Hartl, M.; Flecken, M.; Wang, H.; Popilka, L.; Hartl, F. U.; Bracher, A.
10.1101/2020.05.16.099382 — biochemistry — Posted on 2020-05-16
2364 Enhancer RNAs predict enhancer-gene regulatory links and are critical for enhancer function in neuronal systems
Carullo, N. V. N.; Phillips, R. A.; Simon, R. C.; Roman Soto, S. A.; Hinds, J. E.; Salisbury, A. J.; Revanna, J. S.; Bunner, K. D.; Ianov, L.; Sultan, F. A.; Savell, K. E.; Gersbach, C. A.; Day, J. J.
10.1101/270967 — neuroscience — Posted on 2020-05-16
2365 A taxonomy of seizure dynamotypes
Saggio, M.; Crisp, D.; Scott, J. M.; Karoly, P.; Kuhlmann, L.; Nakatani, M.; Murai, T.; Duempelmann, M.; Schulze-Bonhage, A.; Ikeda, A.; Cook, M.; Gliske, S. V.; Lin, J.; Bernard, C.; Jirsa, V.; Stacey, W. C.
10.1101/2020.02.08.940072 — neuroscience — Posted on 2020-05-16
2368 Higher prevalence of Bacteroides fragilis in Crohn's disease exacerbations and strain-dependent increase of epithelial resistance
Becker, H. E. F.; Jamin, C.; Bervoets, L.; Xu, P.; Pierik, M. J.; Stassen, F. R. M.; Savelkoul, P. H. M.; Penders, J.; Jonkers, D. M. A. E.
10.1101/2020.05.16.099358 — microbiology — Posted on 2020-05-16
2370 Cell-Derived Vesicles as TRPC1 Channel Delivery Systems for the Recovery of Cellular Respiratory and Proliferative Capacities
Kurth, F.; Tai, Y. K.; Parate, D.; van Oostrum, M.; Schmid, Y. R. F.; Toh, S. J.; Yap, J. L. Y.; Wollscheid, B.; Othman, A.; Dittrich, P. S.; Franco-Obregon, A.
10.1101/2020.05.16.099283 — cell biology — Posted on 2020-05-16
2371 Multifocal imaging for precise, label-free tracking of fast biological processes in 3D
Hansen, J. N.; Gong, A.; Wachten, D.; Pascal, R.; Turpin, A.; Jikeli, J. F.; Kaupp, U. B.; Alvarez, L.
10.1101/2020.05.16.099390 — cell biology — Posted on 2020-05-16
2372 A cell competition-based drug screen identifies a novel compound that induces dual c-Myc degradation and p53 activation
Tadele, D. S.; Robertson, J. M.; Crispin, R.; Herrera, M. C.; Chlubnova, M.; Piechaczyk, L. I.; Ayuda-Duran, P.; Singh, S. K.; Gedde-Dahl, T.; Floisand, Y.; Skavland, J.; Wesche, J.; Gjertsen, B.-T.; Enserink, J. M.
10.1101/2020.05.16.089755 — cancer biology — Posted on 2020-05-16
2376 The structural variation landscape in 492 Atlantic salmon genomes
Bertolotti, A. C.; Layer, R. M.; Gundappa, M. K.; Gallagher, M. D.; Pehlivanoglu, E.; Nome, T.; Robledo, D. M.; Kent, M. P.; Rosaeg, L. L.; Holen, M.; Mulugeta, T.; Ashton, T. J.; Hindar, K.; Saegrov, H.; Floro-Larsen, B.; Erkinaro, J.; Primmer, C. R.; Bernatchez, L.; Martin, S. A. M.; Johnston, I. A.; Sandve, S. R.; Lien, S.; Macqueen, D. J.
10.1101/2020.05.16.099614 — genomics — Posted on 2020-05-16
2377 A comprehensive germline variant and expression analyses of ACE2, TMPRSS2 and SARS-CoV-2 activator FURIN genes from the Middle East: Combating SARS-CoV-2 with precision medicine
Al-Mulla, F.; Mohammad, A.; Madhoun, A. A.; Haddad, D.; Ali, H.; Eaaswarkhanth, M.; John, S. E.; Nizam, R.; Channanath, A.; Abu-Farha, M.; Ahmad, R.; Abubaker, J.; Thangavel, A. T.
10.1101/2020.05.16.099176 — genetics — Posted on 2020-05-16
2378 CRYPTOCHROME suppresses the circadian proteome and promotes protein homeostasis
Wong, D. C. S.; Seinkmane, E.; Stangherlin, A.; Zeng, A.; Rzechorzek, N. M.; Beale, A. D.; Day, J.; Reed, M.; Peak-Chew, S. Y.; Putker, M.; O'Neill, J. S.
10.1101/2020.05.16.099556 — cell biology — Posted on 2020-05-16
2381 Loss of FSTL1-expressing adipocyte progenitors drives the age-related involution of brown adipose tissue
Huang, Z.; Zhang, Z.; Heck, R.; Hu, P.; Nanda, H.; Ren, K.; Sun, Z.; Bartolomucci, A.; Gao, Y.; Chung, D.; Zhu, W.; Shen, S.; Ruan, H.-B.
10.1101/2020.05.14.096990 — physiology — Posted on 2020-05-16
2384 Let it bud: an ultrastructural study of Cryptococcus neoformans surface during budding events
Araujo, G. R. d. S.; Alcantara, C. d. L.; Rodrigues, N.; de Souza, W.; Pontes, B.; Frases, S.
10.1101/2020.05.15.098913 — microbiology — Posted on 2020-05-16
2386 Replicating infant astrocyte behavior in the adult after brain injury improves outcomes
Teo, L.; Boghdadi, A. G.; Homman-Ludiye, J.; Mundinano, I.-C.; Kwan, W. C.; Bourne, J. A.
10.1101/2020.05.14.096974 — neuroscience — Posted on 2020-05-16
2387 Elevated dietary ω-6 polyunsaturated fatty acids induce reversible peripheral nerve dysfunction that exacerbates comorbid pain conditions
Boyd, J. T.; LoCoco, P. M.; Furr, A. R.; Bendele, M. R.; Tram, M.; Li, Q.; Chang, F.-M.; Colley, M. E.; Arris, D. A.; Locke, E. E.; Bach, S. B.; Tobon, A.; Ruparel, S. B.; Hargreaves, K. M.
10.1101/2020.05.15.077164 — neuroscience — Posted on 2020-05-16
2389 Community-scale Synchronization and Temporal Partitioning of Gene Expression, Metabolism, and Lipid Biosynthesis in Oligotrophic Ocean Surface Waters
Muratore, D.; Boysen, A. K.; Harke, M. J.; Becker, K. W.; Casey, J. R.; Coesel, S. N.; Mende, D. R.; Wilson, S. T.; Aylward, F. O.; Eppley, J. M.; Vislova, A.; Peng, S.; Rodriguez-Gonzalez, R. A.; Beckett, S. J.; Armbrust, E. V.; DeLong, E. F.; Karl, D. M.; White, A. E.; Zehr, J. P.; Van Mooy, B. A. S.; Dyhrman, S. T.; Ingalls, A. E.; Weitz, J. S.
10.1101/2020.05.15.098020 — ecology — Posted on 2020-05-16
2390 A SNAI2-PEAK1 stromal axis drives progression and lapatinib resistance in HER2-positive breast cancer by supporting a cytokine expression profile that converges on PI3K/Akt signaling
Hamalian, S.; Güth, R.; Runa, F.; Molnar, J.; Vickers, E.; Agajanian, M.; Humphries, J. D.; Humphries, M. J.; Tchou, J. C.; Zervantonakis, I.; Kelber, J.
10.1101/2020.05.15.098772 — cancer biology — Posted on 2020-05-16
2392 Hsp70 chaperone blocks α-synuclein oligomer formation via a novel engagement mechanism
Tao, J.; Berthet, A.; Citron, R.; Stanley, R.; Gestwicki, J.; Agard, D. A.; McConlogue, L.
10.1101/2020.05.15.098699 — neuroscience — Posted on 2020-05-16
2394 Algorithms for the selection of fluorescent reporters
Vaidyanathan, P.; Appleton, E.; Tran, D.; Vahid, A.; Church, G.; Densmore, D.
10.1101/2020.05.15.098186 — bioinformatics — Posted on 2020-05-16
2396 Acute Exercise Following Skill Practice Promotes Motor Memory Consolidation in Parkinson's Disease
Wanner, P.; Winterholler, M.; Gassner, H.; Winkler, J.; Klucken, J.; Pfeifer, K.; Steib, S.
10.1101/2020.05.15.097394 — neuroscience — Posted on 2020-05-16
2398 Correlates of auditory decision making in prefrontal, auditory, and basal lateral amygdala cortical areas
Napoli, J. L.; Camalier, C. R.; Brown, A. L.; Jacobs, J.; Mishkin, M. M.; Averbeck, B. B.
10.1101/2020.05.14.096263 — neuroscience — Posted on 2020-05-16
2399 Stress induces divergent gene expression among lateral habenula efferent pathways
Levinstein, M. R.; Coffey, K. R.; Marx, R. G.; Lesiak, A. J.; Neumaier, J. F.
10.1101/2020.05.15.098319 — neuroscience — Posted on 2020-05-16
2403 Mapping Cognitive Brain Functions at Scale
Balasubramani, P. P.; Ojeda, A.; Maric, V.; Le, H.; Grennan, G.; Alim, F.; Zafar-Khan, M.; Diaz-Delgado, J.; Silveira, S.; Ramanathan, D.; Mishra, J.
10.1101/2020.05.14.097014 — neuroscience — Posted on 2020-05-16
2404 intern: Integrated Toolkit for Extensible and Reproducible Neuroscience
Matelsky, J. K.; Rodriguez, L.; Xenes, D.; Gion, T.; Hider, R.; Wester, B.; Gray-Roncal, W.
10.1101/2020.05.15.098707 — neuroscience — Posted on 2020-05-16
2405 Non-thalamic origin of zebrafish sensory relay nucleus: convergent evolution of visual pathways in amniotes and teleosts
Bloch, S.; Hagio, H.; Thomas, M.; Heuze, A.; Hermel, J.-M.; Lasserre, E.; Colin, I.; Saka, K.; Affaticati, P.; Jenett, A.; Kawakami, K.; Yamamoto, N.; Yamamoto, K.
10.1101/2020.05.16.099010 — neuroscience — Posted on 2020-05-16
2406 Astrocytes close a critical period of motor circuit plasticity
Ackerman, S. D.; Perez-Catalan, N. A.; Freeman, M. R.; Doe, C. Q.
10.1101/2020.05.15.098608 — neuroscience — Posted on 2020-05-16
2408 Resource availability and availability and disturbance shape maximum tree height across the Amazon
Gorgens, E. B.; Nunes, M. H.; Jackson, T.; Coomes, D.; Keller, M.; Reis, C. R.; Valbuena, R.; Rosette, J.; Almeida, D. R. A.; Gimenez, B.; Cantinho, R. Z.; Motta, A. Z.; Assis, M.; Pereira, F. R. d. S.; Spanner, G.; Higuchi, N.; Ometto, J. P.
10.1101/2020.05.15.097683 — ecology — Posted on 2020-05-16
2410 Mitigation of radiation damage in macromolecules via tunable ultrafast stroboscopic TEM
Choe, H.; Ponomarev, I.; Montgomery, E.; Lau, J. W.; Zhu, Y.; Zhao, Y.; Liu, A.; Kanareykin, A.; Jing, C.
10.1101/2020.05.15.099036 — biophysics — Posted on 2020-05-16
2411 Multi-channel intraneural vagus nerve recordings with a novel high-density carbon fiber microelectrode array
Jiman, A. A.; Ratze, D. C.; Welle, E. J.; Patel, P. R.; Richie, J. M.; Bottorff, E. C.; Seymour, J. P.; Chestek, C. A.; Bruns, T. M.
10.1101/2020.05.15.098301 — bioengineering — Posted on 2020-05-16
2413 A system-view of B. pertussis booster vaccine responses in adults primed with whole-cell vs. acellular vaccine in infancy
da Silva Antunes, R.; Pomaznoy, M.; Soldevila, F.; Babor, M.; Bennett, J.; Tian, Y.; Khalil, N.; Qian, Y.; Mandava, A.; Scheuermann, R. H.; Cortese, M.; Pulendran, B.; Petro, C. D.; Gilkes, A.; Purcell, L. A.; Sette, A.; Peters, B.
10.1101/2020.05.15.098830 — systems biology — Posted on 2020-05-16
2415 Superior Colliculus-Projected GABAergic Retinal Ganglion Cells Mediate Looming-Evoked Flight Response
Luo, X.; Cai, D.; Shen, K.; Deng, Q.; Lei, X.; Jin, S.; Zeng, W.-B.; Li, H.; Xu, F.; Huang, L.; Ren, C.; Luo, M.-H.; Xie, T.; Shen, Y.
10.1101/2020.05.14.090167 — neuroscience — Posted on 2020-05-16
2419 Guiding and interpreting brain network classification with transcriptional data
Li, M.; Kessler, D.; Arroyo, J.; Freytag, S.; Bahlo, M.; Levina, E.; Yang, J. Y. H.
10.1101/2020.05.15.099028 — bioinformatics — Posted on 2020-05-16
2421 Machine Learning Identifies Novel Candidates for DrugRepurposing in Alzheimer's Disease
Rodriguez, S.; Hug, C.; Todorov, P.; Moret, N.; Boswell, S. A.; Evans, K.; Zhou, G.; Johnson, N. T.; Hyman, B.; Sorger, P.; Albers, M. W.; Sokolov, A.
10.1101/2020.05.15.098749 — neuroscience — Posted on 2020-05-16
2423 Multifocal tDCS modulates resting-state functional connectivity in older adults depending on induced electric field and baseline connectivity
Abellaneda-Perez, K.; Vaque-Alcazar, L.; Perellon-Alfonso, R.; Sole-Padulles, C.; Bargallo, N.; Salvador, R.; Ruffini, G.; Nitsche, M.; Pascual-Leone, A.; Bartres-Faz, D.
10.1101/2020.05.15.090860 — neuroscience — Posted on 2020-05-16
2425 Measuring Metacognition of Direct and Indirect Parameters of Voluntary Movement
Arbuzova, P.; Peters, C.; Roed, L.; Koss, C.; Maurer, H.; Maurer, L. K.; Mueller, H.; Verrel, J.; Filevich, E.
10.1101/2020.05.14.092189 — neuroscience — Posted on 2020-05-16
2426 Single-cell regulatory landscape and disease vulnerability map of adult Macaque cortex
Lei, Y.; Cheng, M.; Li, Z.; Zhuang, Z.; Wu, L.; Han, L.; Liu, S.; Huang, Z.; Wei, J.; Wang, Y.; Wang, Z.; Xu, L.; Pan, T.; Xie, J.; Liu, C.; Volpe, G.; Ward, C.; Lai, Y.; Xu, J.; Yuan, Y.; Wang, M.; Yu, H.; Sun, H.; Yu, Q.; Wu, L.; Chen, D.; Wang, C.; Wong, C. W.; Liu, W.; Xu, L.; Shang, Z.; Li, G.; Ma, K.; Cheng, L.; Ling, F.; Tan, T.; Chen, K.; Chen, A.; Tasic, B.; Dean, M.; Ji, W.; Yang, H.; Gu, Y.; Esteban, M. A.; Xu, X.; Zeng, H.; Liu, L.; Niu, Y.; Hou, Y.; Liu, S.
10.1101/2020.05.14.087601 — neuroscience — Posted on 2020-05-16
2429 Loss of Photosynthetic Rhythm Thermal Plasticity Under Domestication and RepurposingDrivers of Circadian Clock (DOC) Loci for Adaptive Breeding in Barley
Prusty, M. R.; Bdolach, E.; Yamamoto, E.; Neyhart, J. L.; Tiwari, L. D.; Pillen, K.; Feigenbaum, A. D. D.; Smith, K. P.; Fridman, E.
10.1101/2020.05.15.098418 — genetics — Posted on 2020-05-16
2430 Quantitative in vivo bioluminescence imaging of orthotopic patient-derived glioblastoma xenografts
Koessinger, A. L.; Koessinger, D.; Stevenson, K.; Cloix, C.; Mitchell, L.; Chalmers, A. J.; Norman, J. C.; Tait, S. W.
10.1101/2020.05.15.098640 — cancer biology — Posted on 2020-05-16
2431 A Novel Xenonucleic Acid Mediated Molecular Clamping Technology for Early Colorectal Cancer Screening
Sun, Q.; Pastor, L.; Du, J.; Powell, M.; Zhang, A.; Bodmer, W.; Wu, J.; Zheng, S.; Sha, M. Y.
10.1101/2020.05.15.098954 — cancer biology — Posted on 2020-05-16
2432 Single-cell RNA-sequencing of peripheral neuroblastic tumors reveals an aggressive transitional cell state at the junction of an adrenergic-mesenchymal transdifferentiation trajectory
Yuan, X.; Seneviratne, J. A.; Du, S.; Xu, Y.; Chen, Y.; Jin, Q.; Jin, X.; Balachandran, A.; Huang, S.; Xu, Y.; Zhai, Y.; Lu, L.; Tang, M.; Dong, Y.; Cheung, B. B.; Marshall, G. M.; Shi, W.; Zhang, C.; Carter, D. R.
10.1101/2020.05.15.097469 — cancer biology — Posted on 2020-05-16
2439 Evaluation of cerebellar function scores in relation to cerebellar axonal loss in multiple sclerosis
Boonstra, F.; Gajamange, S.; Noffs, G.; Perera, T.; Strik, M.; Vogel, A.; Butzkueven, H.; Evans, A.; van der Walt, A.; Kolbe, S.
10.1101/2020.05.15.094938 — neuroscience — Posted on 2020-05-16
2440 Enzymatic dissociation induces transcriptional and proteotype bias in brain cell populations
Mattei, D.; Ivanov, A.; van Oostrum, M.; Pantelyushin, S.; Richetto, J.; Mueller, F.; Beffinger, M. M.; Schellhammer, L.; vom Berg, J.; Wollscheid, B.; Beule, D.; Paolicelli, R. C.; Meyer, U.
10.1101/2020.05.14.095422 — neuroscience — Posted on 2020-05-16
2441 The demographic buffering strategy has a threshold of effectiveness to increases in environmental stochasticity
Rodriguez-Caro, R. C.; Capdevila, P.; Gracia, E.; Barbosa, J. M.; Gimenez, A.; Salguero-Gomez, R.
10.1101/2020.05.15.098095 — ecology — Posted on 2020-05-16
2442 Spatiotemporal Evaluation of The Human Footprint in Colombia: Four Decades of Anthropic Impact in Highly Biodiverse Ecosystems
Correa Ayram, C. A.; Rothlisberger, A. E.; Diaz Timote, J. J.; Rodriguez Buritica, S.; Ramirez, W.; Corzo, G.
10.1101/2020.05.15.098855 — ecology — Posted on 2020-05-16
2449 Neuronal and glial 3D chromatin architecture illustrates cellular etiology of brain disorders
Hu, B.; Won, H.; Mah, W.; Park, R.; Kassim, B.; Spiess, K.; Kozlenkov, A.; Crowley, C. A.; Pochareddy, S.; Li, Y.; Dracheva, S.; Sestan, N.; Akbarian, S.; Geschwind, D.
10.1101/2020.05.14.096917 — neuroscience — Posted on 2020-05-16
2451 Profiling of small non-coding RNAs across cellular and biofluid compartments: implications for multiple sclerosis immunopathology
Zheleznyakova, G. Y.; Piket, E.; Needhamsen, M.; Hagemann-Jensen, M.; Ekman, D.; Khademi, M.; Al Nimer, F.; Scicluna, P.; Faridani, O. R.; Olsson, T.; Piehl, F.; Jagodic, M.
10.1101/2020.05.15.097519 — molecular biology — Posted on 2020-05-16
2453 Habitat loss causes long transients in small trophic chains
Vidiella Rocamora, B.; Valverde, S.; Fontich, E.; Sardanyes, J.
10.1101/2020.05.15.098863 — ecology — Posted on 2020-05-16
2463 Shifting carbon flux from non-transient starch to lipid allows oil accumulation in transgenic tobacco leaves
Chu, K.; Jenkins, L. M.; Bailey, S. R.; Kambhampati, S.; Koley, S.; Foley, K.; Arp, J. J.; Czymmek, K. J.; Bates, P. D.; Allen, D. K.
10.1101/2020.05.15.098632 — plant biology — Posted on 2020-05-16
2464 Pituitary Tumor Transforming Gene 1 orchestrates gene regulatory variation in mouse ventral midbrain during aging
Gui, Y.; Thomas, M. H.; Garcia, P.; Karout, M.; Halder, R.; Michelucci, A.; Kollmus, H.; Zhou, C.; Melmed, S.; Schughart, K.; Balling, R.; Mittelbronn, M.; Nadeau, J. H.; Williams, R. W.; Sauter, T.; Buttini, M.; Sinkkonen, L.
10.1101/2020.05.14.096156 — genomics — Posted on 2020-05-16
2470 Eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis
O'Neill, J.; Hoyle, N. P.; Robertson, J. B.; Edgar, R. S.; Beale, A. D.; Peak-Chew, S. Y.; Day, J.; Costa, A. S. H.; Frezza, C.; Causton, H. C.
10.1101/2020.05.14.095521 — molecular biology — Posted on 2020-05-16
2475 TOR signaling modulates Cdk8-dependent GAL gene expression in Saccharomyces cerevisiae
Hawe, N.; Mestnikov, K.; Horvath, R.; Eji-Lasisi, M.; Lam, C.; Rohde, J. R.; Sadowski, I.
10.1101/2020.05.15.097576 — genetics — Posted on 2020-05-16
2476 p53 induces ARTS to promote mitochondrial apoptosis
Hao, Q.; Chen, J.; Liao, J.; Huang, Y.; Larisch, S.; Zeng, S. X.; Lu, H.; Zhou, X.
10.1101/2020.05.14.096982 — cancer biology — Posted on 2020-05-16
2477 Sulfur reduction coupled with anaerobic ammonium oxidation drove prebiotic proto-anabolic networks
Bao, P.; Li, G.-X.; Zhao, J.-Y.; Wu, K.; Wang, J.; Jia, X.-Y.; Zhang, H.-E.; He, Y.-Q.; Li, H.
10.1101/461707 — biochemistry — Posted on 2020-05-16
2478 JAG1-NOTCH4 MECHANOSENSING DRIVES ATHEROSCLEROSIS
Souilhol, C.; Li, X.; Canham, L.; Roddie, H.; Pirri, D.; Tardajos Ayllon, B.; Chambers, E.; Dunning, M.; Ariaans, M.; Li, J.; Fang, Y.; FRAGIADAKI, M.; Ridger, V.; Serbanovic-Canic, J.; De Val, S.; Francis, S.; Chico, T. J.; Evans, P.
10.1101/2020.05.15.097931 — pathology — Posted on 2020-05-16
2480 Late Quaternary habitat suitability models for chimpanzees (Pan troglodytes) since the Last Interglacial (120,000 BP)
Barratt, C. D.; Lester, J. D.; Gratton, P.; Onstein, R. E.; Kalan, A. K.; McCarthy, M. S.; Bocksberger, G.; White, L. C.; Vigilant, L.; Dieguez, P.; Boesch, C.; Arandjelovic, M.; Kuehl, H.
10.1101/2020.05.15.066662 — ecology — Posted on 2020-05-16
2482 Evolutionary Changes in Left-Right Visceral Asymmetry in Astyanax Cavefish
Ma, L.; Ng, M.; Shi, J.; Gore, A. V.; Castranova, D.; Weinstein, B. M.; Jeffery, W. R.
10.1101/2020.05.15.098483 — developmental biology — Posted on 2020-05-16
2483 RIPK2 Stabilizes c-Myc and is an Actionable Target for Inhibiting Prostate Cancer Metastasis
Yan, Y.; Zhou, B.; Qian, C.; Vasquez, A.; Chatterjee, A.; Yuan, X.; Posadas, E.; Kyprianou, N.; Knudsen, B. S.; Murali, R.; Gertych, A.; You, S.; Freeman, M. R.; Yang, W.
10.1101/2020.05.14.096867 — cancer biology — Posted on 2020-05-16
2484 PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response
Li, J.; Kaneda, M. M.; Ma, J.; Li, M.; Patel, K.; Koga, T.; Sarver, A. L.; Furnari, F.; Xu, B.; Dhawan, S.; Ning, J.; Zhu, H.; Wu, A.; You, G.; Jiang, T.; Venteichera, A. S.; Rich, J. N.; Glass, C. K.; Varner, J. A.; Chen, C. C.
10.1101/2020.05.14.097121 — cancer biology — Posted on 2020-05-16
2486 Glucocorticoid signaling in pancreatic islets modulates gene regulatory programs and genetic risk of type 2 diabetes
Aylward, A.; Okino, M.-L.; Benaglio, P.; Chiou, J.; Beebe, E.; Padilla, J. A.; Diep, S.; Gaulton, K. J.
10.1101/2020.05.15.038679 — genomics — Posted on 2020-05-16
2487 Soil microbial diversity and litter decomposition increase along a recovery gradient in tropical montane forests of Malaysian Borneo
Sniegocki, R.; Moon, J. B.; Rutrough, A.; gireneus, J.; Sathiya, J. S. S.; Weindorf, D. C.; Farmer, M. C.; Naithani, K.
10.1101/2020.05.14.096883 — ecology — Posted on 2020-05-16
2490 Expression changes in immune and epigenetic gene pathways associated with nutritional metabolites in maternal blood from pregnancies resulting in autism and atypical neurodevelopment
Zhu, Y.; Mordaunt, C. E.; Durbin-Johnson, B. P.; Caudill, M. A.; Malysheva, O. V.; Miller, J. W.; Green, R.; James, S. J.; Melnyk, S. B.; Fallin, M. D.; Hertz-Picciotto, I.; Schmidt, R. J.; LaSalle, J. M.
10.1101/2020.05.14.096586 — bioinformatics — Posted on 2020-05-16
2494 Spider viscid silk sticks better to superhydrophobic surfaces
Alicea-Serrano, A. M.; Htut, K. Z.; Coonfield, A. J.; Karkosiak, K.; Dhinojwala, A.; Blackledge, T. A.
10.1101/2020.05.15.098194 — evolutionary biology — Posted on 2020-05-16
2497 Analyzing editosome function in high-throughput
Del Campo, C.; Leeder, W.-M.; Reissig, P.; Göringer, H. U.
10.1101/2020.05.15.096370 — molecular biology — Posted on 2020-05-16
2498 Genome-wide association analysis and replication in 810,625 individuals identifies novel therapeutic targets for varicose veins
Ahmed, W.-U.-R.; Wiberg, A.; Ng, M.; Wang, W.; Auton, A.; 23andMe Research Team, ; Lee, R.; Handa, A.; Zondervan, K. T.; Furniss, D.
10.1101/2020.05.14.095653 — genetics — Posted on 2020-05-16
2500 Evaluating assembly and variant calling software for strain-resolved analysis of large DNA-viruses
Deng, Z.-L.; Dhingra, A.; Fritz, A.; Goetting, J.; Muench, P.; Steinbrueck, L.; Schulz, T.; Ganzenmueller, T.; McHardy, A. C.
10.1101/2020.05.14.095265 — bioinformatics — Posted on 2020-05-16
2501 The architecture of EMC reveals a path for membrane protein insertion
O'Donnell, J. P.; Phillips, B. P.; Yagita, Y.; Juszkiewicz, S.; Wagner, A.; Malinverni, D.; Keenan, R. J.; Miller, E. A.; Hegde, R. S.
10.1101/2020.05.15.098574 — biochemistry — Posted on 2020-05-16
2502 Ectopic bone formation and systemic bone loss in a transmembrane TNF-driven model of human spondyloarthritis
Christodoulou-Vafeiadou, E.; Geka, C.; Ntari, L.; Kranidioti, K.; Argyropoulou, E.; Meier, F.; Armaka, M.; Mourouzis, I.; Pantos, C.; Rouchota, M.; Loudos, G.; Denis, M. C.; Karagianni, N.; Kollias, G.
10.1101/2020.05.14.095588 — pathology — Posted on 2020-05-16
2504 LC3B phosphorylation regulates FYCO1 binding anddirectional transport of autophagosomes
Nieto Torres, J. L.; Shanahan, S.-L.; Chassefeyre, R.; Landeras Bueno, S.; Encalada, S. E.; Hansen, M.
10.1101/2020.05.15.081638 — molecular biology — Posted on 2020-05-16
2505 Peptide YY: a novel Paneth cell antimicrobial peptide that maintains fungal commensalism
Pierre, J. F.; La Torre, D.; Sidebottom, A.; Kambal, A.; Zhu, X.; Tao, Y.; Cham, C. M.; Wang, L.; Harris, K. G.; Zaborina, O.; Alverdy, J. C.; Witchley, J.; Noble, S. M.; Chang, E. B.
10.1101/2020.05.15.096875 — molecular biology — Posted on 2020-05-16
2507 Direct and indirect effects of maternal, paternal, and offspring genotypes: Trio-GCTA
Eilertsen, E. M.; Jami, E. S.; McAdams, T. A.; Hannigan, L. J.; Havdahl, A. S.; Magnus, P. M.; Evans, D. M.; Ystrom, E.
10.1101/2020.05.15.097840 — genetics — Posted on 2020-05-16
2511 Clonal Heterogeneity Supports Mitochondrial Metabolism in Pancreatic Cancer
Halbrook, C. J.; Thurston, G.; McCarthy, A.; Nelson, B. S.; Sajjakulnukit, P.; Krall, A. S.; Mullen, P. J.; Zhang, L.; Batra, S.; Viale, A.; Stanger, B. Z.; Cristofk, H. R.; Zhang, J.; Pasca di Magliano, M.; Jorgensen, C.; Lyssiotis, C. A.
10.1101/2020.05.15.098368 — cancer biology — Posted on 2020-05-16
2513 LiBis: An ultrasensitive alignment method for low-input bisulfite sequencing
Yin, Y.; Li, J.; Li, J.; Lee, M.; Zhao, S.; Guo, L.; Li, J.; Zhang, M.; Huang, Y.; Li, X.-N.; Sun, D.
10.1101/2020.05.14.096461 — bioinformatics — Posted on 2020-05-16
2514 Electromembrane extraction and mass spectrometry for liver organoid drug metabolism studies
Skottvoll, F. S.; Hansen, F.; Harrison, S.; Boger, I. C. S.; Mrsa, A.; Restan, M. S.; Stein, M.; Lundanes, E.; Pedersen-Bjergaard, S.; Aizenshtadt, A.; Krauss, S.; Sullivan, G. J.; Bogen, I. L.; Wilson, S. R.
10.1101/2020.05.15.095174 — biochemistry — Posted on 2020-05-16
2517 A bimodular PKS platform that expands the biological design space
Zargar, A.; Valencia, L.; Wang, J.; Chang, S.; Werts, M.; Wong, A.; Benites, V.; Baidoo, E.; Katz, L.; Keasling, J. D.
10.1101/2020.05.14.096743 — synthetic biology — Posted on 2020-05-16
2518 A complex resistance locus in Solanum americanum recognizes a conserved Phytophthora effector
Witek, K.; Lin, X.; Karki, H. S.; Jupe, F.; Witek, A. I.; Steuernagel, B.; Stam, R.; Van Oosterhout, C.; Fairhead, S.; Cocker, J. M.; Bhanvadia, S.; Barrett, W.; Song, T.; Vleeshouwers, V. G.; Tomlinson, L.; Wulff, B. B.; Jones, J. D.
10.1101/2020.05.15.095497 — plant biology — Posted on 2020-05-16
2527 A chromosome-level assembly of the black tiger shrimp (Penaeus monodon) genome facilitates the identification of novel growth-associated genes
Uengwetwanit, T.; Pootakham, W.; Nookaew, I.; Sonthirod, C.; Angthong, P.; Sittikankaew, K.; Rungrassamee, W.; Arayamethakorn, S.; Wongsurawat, T.; Jenjaroenpun, P.; Sangsrakru, D.; Leelatanawit, R.; Khudet, J.; Koehorst, J. J.; Schaap, P. J.; Martins dos Santos, V. A. P.; Tangy, F.; Karoonuthaisiri, N.
10.1101/2020.05.14.096073 — genomics — Posted on 2020-05-16
2533 Aberrant claudin-6-adhesion signal promotes endometrial cancer progression via estrogen receptor α
Kojima, M.; Sugimoto, K.; Tanaka, M.; Endo, Y.; Ichikawa-Tomikawa, N.; Kashiwagi, K.; Kato, H.; Honda, T.; Furukawa, S.; Nishiyama, H.; Watanabe, T.; Soeda, S.; Fujimori, K.; Chiba, H.
10.1101/2020.05.15.097659 — cancer biology — Posted on 2020-05-16
2534 Interplay of folded domains and the disordered low-complexity domain in mediating hnRNPA1 phase separation
Milkovic, N. M.; Thomasen, F. E.; Cuneo, M. J.; Grace, C. R.; Martin, E. W.; Nourse, A.; Lindorff-Larsen, K.; Mittag, T.
10.1101/2020.05.15.096966 — biophysics — Posted on 2020-05-16
2540 Effect of short-term prescription opioids on DNA methylation of the OPRM1 promoter
Sandoval-Sierra, J. V.; García, F. I. S.; Brooks, J. H.; Derefinko, K. J.; Mozhui, K.
10.1101/2020.01.24.919084 — genomics — Posted on 2020-05-16
2541 EM-seq: Detection of DNA Methylation at Single Base Resolution from Picograms of DNA
Vaisvila, R.; Ponnaluri, V. K. C.; Sun, Z.; Langhorst, B. W.; Saleh, L.; Guan, S.; Dai, N.; Campbell, M. A.; Sexton, B. S.; Marks, K.; Samaranayake, M.; Samuelson, J. C.; Church, H. E.; Tamanaha, E.; Correa, I. R.; Pradhan, S.; Dimalanta, E. T.; Evans, T. C.; Williams, L.; Davis, T. B.
10.1101/2019.12.20.884692 — genomics — Posted on 2020-05-16
2542 Polarized endosome dynamics engage cytosolic Par-3 and dynein during asymmetric division
Zhao, X.; Tong, K.; Chen, x.; Yang, B.; Li, Q.; Dai, Z.; Shi, X.; Seiple, I.; Huang, B.; Guo, S.
10.1101/2020.05.15.098012 — cell biology — Posted on 2020-05-16
2543 Distortion correction of diffusion weighted MRI without reverse phase-encoding scans or field-maps
Schilling, K. G.; Blaber, J.; Hansen, C.; Cai, L.; Rogers, B.; Anderson, A. W.; Smith, S.; Kanakaraj, P.; Rex, T.; Resnick, S. M.; Shafer, A. T.; Cutting, L.; Woodward, N.; Zald, D.; Landman, B. A.
10.1101/2020.01.19.911784 — bioengineering — Posted on 2020-05-16
2544 Recurrent processing drives experience-dependent plasticity for perceptual decisions
Jia, K.; Zamboni, E.; Kemper, V.; Rua, C.; Goncalves, N. R.; Ng, A. K. T.; Rodgers, C.; Williams, G.; Goebel, R.; Kourtzi, Z.
10.1101/2020.04.07.030510 — neuroscience — Posted on 2020-05-15
2545 A freshwater radiation of diplonemids
Mukherjee, I.; Salcher, M. M.; Andrei, A.-S.; Kavagutti, V.; Shabarova, T.; Grujcic, V.; Haber, M.; Layoun, P.; Hodoki, Y.; Nakano, S.-i.; Simek, K.; Ghai, R.
10.1101/2020.05.14.095992 — microbiology — Posted on 2020-05-15
2546 Increased antibiotic susceptibility in Neisseria gonorrhoeae through adaptation to the cervical environment
Ma, K. C.; Mortimer, T. D.; Hicks, A. L.; Wheeler, N. E.; Sanchez-Buso, L.; Golparian, D.; Taiaroa, G.; Rubin, D. H.; Wang, Y.; Williamson, D. A.; Unemo, M.; Harris, S. R.; Grad, Y. H.
10.1101/2020.01.07.896696 — microbiology — Posted on 2020-05-15
2551 Dynamic dopaminergic activity controls the timing of self-timed movement
Hamilos, A. E.; Spedicato, G.; Hong, Y.; Sun, F.; Li, Y.; Assad, J. A.
10.1101/2020.05.13.094904 — neuroscience — Posted on 2020-05-15
2553 Genomic diversity of Escherichia coli isolates from backyard chickens and guinea fowl in the Gambia
Foster-Nyarko, E.; Alikhan, N.-F.; Ravi, A.; Thomson, N. M.; Jarju, S.; Kwambana-Adams, B. A.; Secka, A.; O'Grady, J.; Antonio, M.; PALLEN, M. J.
10.1101/2020.05.14.096289 — genomics — Posted on 2020-05-15
2556 MEKK3-MEK5-ERK5 signaling promotes mitochondrial degradation
Craig, J. E.; Miller, J. N.; Rayavarapu, R. R.; Hong, Z.; Bulut, G. B.; Zhuang, W.; Sakurada, S. M.; Temirov, J.; Low, J. A.; Chen, T.; Pruett-Miller, S. M.; Huang, L. J.-s.; Potts, M. B.
10.1101/2020.05.15.098442 — cell biology — Posted on 2020-05-15
2557 Structure and function of stator units of the bacterial flagellar motor
Santiveri, M.; Roa-Eguiara, A.; Kuhne, C.; Wadhwa, N.; Berg, H. C.; Erhardt, M.; Taylor, N. M. I.
10.1101/2020.05.15.096610 — biophysics — Posted on 2020-05-15
2564 Improved RAD51 binders through motif shuffling based on the modularity of BRC repeats
Lindenburg, L.; Pantelejevs, T.; Gielen, F.; Zuazua-Villar, P.; Butz, M.; Rees, E. J.; Kaminski, C. F.; Downs, J.; Hyvonen, M.; Hollfelder, F.
10.1101/2020.05.14.097071 — biochemistry — Posted on 2020-05-15
2569 Citric Acid Water as an Alternative to Water Restriction for High-Yield Mouse Behavior
Urai, A. E.; Aguillon-Rodriguez, V.; Laranjeira, I.; Cazettes, F.; The International Brain Laboratory, ; Mainen, Z. F.; Churchland, A. K.
10.1101/2020.03.02.973016 — neuroscience — Posted on 2020-05-15
2570 Transplacental innate immune training via maternal microbial exposure: a central role for the XBP1-ERN1 axis in programming dendritic cell precursors
Mincham, K. T.; Jones, A. C.; Bodinier, M.; Scott, N. M.; Lauzon-Joset, J.-F.; Stumbles, P. A.; Bosco, A.; Holt, P. G.; Strickland, D. H.
10.1101/848242 — immunology — Posted on 2020-05-15
2576 Spooky interaction at a distance in cave and surface dwelling electric fishes
Fortune, E.; Andanar, N.; Madhav, M.; Jayakumar, R.; Cowan, N. J.; Bichuette, M. E.; Soares, D.
10.1101/747154 — neuroscience — Posted on 2020-05-15
2577 Distinct pathways of homologous recombination controlled by the SWS1-SWSAP1-SPIDR complex
prakash, r.; sandoval, t.; Morati, F.; Zagelbaum, J. A.; Taylor, B.; Desclos, E. C.; Wang, R.; Sullivan, M. R.; Rein, H. L.; Bernstein, K. A.; Krawczyk, P. M.; Gautier, J.; Modesti, M.; Vanoli, F.; Jasin, M.
10.1101/2020.05.15.098848 — molecular biology — Posted on 2020-05-15
2579 Lytic Reactivation of the Kaposis sarcoma-associated herpesvirus (KSHV) is Accompanied by Major Nucleolar Alterations
Atari, N.; Rajan, K. S.; Chikne, V.; Cohen-Chalamish, S.; Orbaum, O.; Jacob, A.; Kalt, I.; Michaeli, S.; Sarid, R.
10.1101/2020.05.15.097808 — microbiology — Posted on 2020-05-15
2582 Transparency in butterflies and moths: structural diversity, optical properties and ecological relevance
Gomez, D.; Pinna, C.; Pairraire, J.; Arias, M.; Barbut, J.; Pomerantz, A.; Nous, C.; Daney de Marcillac, W.; Berthier, S.; Patel, N.; Andraud, C.; Elias, M.
10.1101/2020.05.14.093450 — evolutionary biology — Posted on 2020-05-15
2584 Field efficacy of guppies and pyriproxyfen (Sumilarv(R) 2MR) combined with community engagement on dengue vectors in Cambodia: a randomized controlled trial
Hustedt, J. C.; Doum, D.; Keo, V.; Ly, S.; Sam, B.; Chan, V.; Alexander, N.; Bradley, J.; Liverani, M.; Prasetyo, D. B.; Rachmat, A.; Shafique, M.; Lopes, S.; Rithea, L.; Hii, J.
10.1101/2020.05.15.097782 — ecology — Posted on 2020-05-15
2585 Evolution and molecular characteristics of SARS-CoV-2 genome
Bai, Y.; Jiang, D.; Lon, J. R.; Chen, X.; Hu, M.; Lin, S.; Chen, Z.; Wang, X.; Meng, Y.; Du, H.
10.1101/2020.04.24.058933 — bioinformatics — Posted on 2020-05-15
2591 Paternal aging causes atypical development of vocal communication in neonatal mice
Mai, L.; Kimura, R.; Inada, H.; Kanno, K.; Matsuda, T.; Tachibana, R. O.; Yoshizaki, K.; Komaki, F.; Osumi, N.
10.1101/738781 — neuroscience — Posted on 2020-05-15
2593 The FDA-approved drug Nelfinavir inhibits lytic cell-free transmission of human adenoviruses
Georgi, F.; Andriasyan, V.; Witte, R.; Murer, L.; Hemmi, S.; Yu, L.; Grove, M.; Meili, N.; Kuttler, F.; Yakimovich, A.; Turcatti, G.; Greber, U. F.
10.1101/2020.05.15.098061 — microbiology — Posted on 2020-05-15
2594 Rumen protozoa shape microbiome composition and metabolic output of fermentation
Solomon, R.; Wein, T.; Levy, B.; Reiss, V.; Zehavi, T.; Furman, O.; Jami, E.
10.1101/2020.05.15.080218 — microbiology — Posted on 2020-05-15
2596 Sensing soluble uric acid by Naip1-Nlrp3 platform
Braga, T. T.; Davanso, M. R.; Mendes, D.; Souza, T. A.; de Brito, A. F.; Cruz, M. C.; Hiyane, M. I.; de Lima, D. S.; Nunes, V.; Giarola, J. d. F.; Souto, D. E. P.; Prochnicki, T.; Lauterbach, M.; Biscaia, S. M. P.; de Freitas, R. A.; Curi, R.; Pontillo, A.; Latz, E.; Camara, N. O. S.
10.1101/2020.05.15.077644 — immunology — Posted on 2020-05-15
2599 Impaired Layer Specific Retinal Vascular Reactivity Among Diabetic Subjects
Singer, M.; Ashimatey, B. S.; Zhou, X.; Chu, Z.; Wang, R.; Kashani, A. H.
10.1101/2020.05.15.097717 — physiology — Posted on 2020-05-15
2601 SARS-CoV2 (COVID-19) Structural/Evolution Dynamicome: Insights into functional evolution and human genomics.
Gupta, R.; Charron, J.; Stenger, C.; Painter, J.; Steward, H.; Cook, T.; Faber, W.; Frisch, A.; Lind, E.; Bauss, J.; Li, X.; Sirpilla, O.; Soehnlen, X.; Underwood, A.; Hinds, D.; Morris, M.; Lamb, N.; Carcillo, J.; Bupp, C.; Uhal, B.; Rajasekaran, S.; Prokop, J. W.
10.1101/2020.05.15.098616 — genetics — Posted on 2020-05-15
2603 PCH-2TRIP13 regulates spindle checkpoint strength
Defachelles, L.; Russo, A. E.; Nelson, C. R.; Bhalla, N.
10.1101/389080 — cell biology — Posted on 2020-05-15
2604 Analysis of SARS-CoV-2 RNA-Sequences by Interpretable Machine Learning Models
Villmann, T.; Kaden, M.; Bohnsack, K. S.; Weber, M.; Kudla, M.; Gutowska, K.; Blazewicz, J.
10.1101/2020.05.15.097741 — bioinformatics — Posted on 2020-05-15
2605 Yeast-Expressed SARS-CoV Recombinant Receptor-Binding Domain (RBD219-N1) Formulated with Alum Induces Protective Immunity and Reduces Immune Enhancement
Chen, W.-H.; Tao, X.; Peng, B.-H.; Pollet, J.; Strych, U.; Bottazzi, M. E.; Hotez, P. J.; Lustigman, S.; Du, L.; Jiang, S.; Tseng, C.-T. K.
10.1101/2020.05.15.098079 — immunology — Posted on 2020-05-15
2606 A single dose SARS-CoV-2 simulating particle vaccine induces potent neutralizing activities
Cai, Y.; Yin, D.; Ling, S.; Tian, X.; Li, Y.; Xu, Z.; Jiang, H.; Zhang, X.; Wang, X.; Shi, Y.; Zhang, Y.; Da, L.; Tao, S.-c.; Wang, Q.; Xu, J.; Ying, T.; Hong, J.
10.1101/2020.05.14.093054 — bioengineering — Posted on 2020-05-15
2607 Favipiravir strikes the SARS-CoV-2 at its Achilles heel, the RNA polymerase
Shannon, A.; Selisko, B.; Le, T.-T.-N.; Huchting, J.; Touret, F.; Piorkowski, G.; Fattorini, V.; Ferron, F.; Decroly, E.; Meier, C.; Coutard, B.; Peersen, O.; Canard, B.
10.1101/2020.05.15.098731 — biochemistry — Posted on 2020-05-15
2608 Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein
Walker, L. M.; Wec, A. Z.; Wrap, D.; Herbert, A. S.; Maurer, D. P.; Haslwanter, D.; Sakharkar, M.; Jangra, R. K.; Dieterle, M. E.; Lilov, A.; Huang, D.; Tse, L. V.; Johnson, N. V.; Hsieh, C.-L.; Wang, N.; Nett, J. H.; Champney, E.; Burnina, I.; Brown, M.; Lin, S.; Sinclair, M.; Johnson, C.; Pudi, S.; Bortz, R.; Wirchnianski, A. S.; Laudermilch, E.; Florez, C.; Fels, J. M.; O'Brien, C. M.; Graham, B. S.; Nemazee, D.; Burton, D. R.; Baric, R. S.; Voss, J. E.; Chandran, K.; Dye, J. M.; McLellan, J. S.
10.1101/2020.05.15.096511 — immunology — Posted on 2020-05-15
2609 Conservation and host-specific expression of non-tandemly repeated heterogenous ribosome RNA gene in arbuscular mycorrhizal fungi
Maeda, T.; Kobayashi, Y.; Nakagawa, T.; Ezawa, T.; Yamaguchi, K.; Bino, T.; Nishimoto, Y.; Shigenobu, S.; Kawaguchi, M.
10.1101/2020.05.14.095489 — genomics — Posted on 2020-05-15
2610 Functional Connectivity of the Precuneus Reflects Effectiveness of Visual Restitution Training in Chronic Hemianopia
Halbertsma, H. N.; Elshout, J. A.; Bergsma, D. P.; Norris, D. G.; Cornelissen, F. W.; van den Berg, A. V.; Haak, K. V.
10.1101/2020.05.14.050310 — neuroscience — Posted on 2020-05-15
2611 BAP31 regulated polarization of macrophages through C/EBP β in cutaneous wound healing
Yuan, Q.; Zhao, B.; Cao, Y.; Yan, J.-c.; Sun, L.-j.; Liu, X.; Xu, Y.; Wang, X.-y.; Wang, B.
10.1101/2020.05.14.095554 — molecular biology — Posted on 2020-05-15
2615 Prediction analysis of SARS-COV-2 entry in Livestock and Wild animals
Praharaj, M. R.; Garg, P.; Khan, R. I. N.; Sharma, S.; Panigrahi, M.; Mishra, B. P.; Mishra, B.; Kumar, G. S.; Gandham, R. K.; Singh, R. K.; Majumdar, S.; Mohapatra, T.
10.1101/2020.05.08.084327 — microbiology — Posted on 2020-05-15
2616 Rapid isolation of potent SARS-CoV-2 neutralizing antibodies and protection in a small animal model
Rogers, T. F.; Zhao, F.; Huang, D.; Beutler, N.; Burns, A.; He, W.-t.; Limbo, O.; Smith, C.; Song, G.; Woehl, J.; Yang, L.; Abbott, R. K.; Callaghan, S.; Garcia, E.; Hurtado, J.; Parren, M.; Peng, L.; Ricketts, J.; Ricciardi, M. K.; Rawlings, S. A.; Smith, D. M.; Nemazee, D.; Teijaro, J. R.; Voss, J. E.; Andrabi, R.; Briney, B.; Landais, E.; Sok, D.; Jardine, J. G.; Burton, D.
10.1101/2020.05.11.088674 — immunology — Posted on 2020-05-15
2618 Predicting the Immunogenicity of T cell epitopes: From HIV to SARS-CoV-2
Gao, A.; Chen, Z.; Segal, F. P.; Carrington, M.; Streeck, H.; Chakraborty, A. K.; Juelg, B.
10.1101/2020.05.14.095885 — immunology — Posted on 2020-05-15
2620 Androgen regulates SARS-CoV-2 receptor levels and is associated with severe COVID-19 symptoms in men
Ghazizadeh, Z.; Majd, H.; Richter, M.; Samuel, R.; Zekavat, S. M.; Asgharian, H.; Farahvashi, S.; Kalantari, A.; Ramirez, J.; Zhao, H.; Natarajan, P.; Goodarzi, H.; Fattahi, F.
10.1101/2020.05.12.091082 — cell biology — Posted on 2020-05-15
2621 Activity profiling and structures of inhibitor-bound SARS-CoV-2-PLpro protease provides a framework for anti-COVID-19 drug design
Rut, W.; Lv, Z.; Zmudzinski, M.; Patchett, S.; Nayak, D.; Snipas, S. J.; El Oualid, F.; Bekes, M.; Huang, T. T.; Drag, M.; Olsen, S. K.
10.1101/2020.04.29.068890 — biochemistry — Posted on 2020-05-15
2624 CRYPTOCHROMES confer robustness, not rhythmicity, to circadian timekeeping
Putker, M.; Wong, D.; Seinkmane, E.; Rzechorzek, N. M.; Zeng, A.; Hoyle, N. P.; Chesham, J. E.; Edwards, M. D.; Feeney, K. A.; Fischer, R.; Peschel, N.; Chen, K.-F.; Selby, C. P.; Sancar, A.; O'Neill, J. S.
10.1101/2020.05.14.095968 — cell biology — Posted on 2020-05-15
2626 Transcriptional profiling reveals TRPM5-expressing cells involved in viral infection in the olfactory epithelium
Baxter, B. D.; Larson, E. D.; Feinstein, P.; Polese, A. G.; Bubak, A. N.; Niemeyer, C. S.; Merle, L.; Shepherd, D.; Ramakrishnan, V. R.; Nagel, M. A.; Restrepo, D.
10.1101/2020.05.14.096016 — neuroscience — Posted on 2020-05-15
2627 Unique roles of ATAC and SAGA KAT2A complexes in normal and malignant hematopoiesis
Arede, L.; Foerner, E.; Wind, S.; Kulkarni, R.; Domingues, A. F.; Kleinwaechter, S.; Gupta, S.; Scheer, E.; Tora, L.; Pina, C.
10.1101/2020.05.14.096057 — cell biology — Posted on 2020-05-15
2630 Experimental glaucoma retinal proteomics identifies mutually exclusive and overlapping molecular characteristics with human glaucoma
Mirzaei, M.; Gupta, V.; Chitranshi, N.; Deng, L.; Pushpitha, K.; Abbasi, M.; Chick, J.; Rajput, R.; Wu, Y.; McKay, M. J.; Salekdeh, G. H.; Gupta, V.; Haynes, P. A.; Graham, S.
10.1101/2020.05.14.095307 — neuroscience — Posted on 2020-05-15
2631 Sequence Characterization and Molecular Modeling of Clinically Relevant Variants of the SARS-CoV-2 Main Protease
Cross, T. J.; Takahashi, G. R.; Diessner, E. M.; Crosby, M. G.; Farahmand, V.; Zhuang, S.; Butts, C. T.; Martin, R. W.
10.1101/2020.05.15.097493 — molecular biology — Posted on 2020-05-15
2632 Distribution of ACE2, CD147, cyclophilins, CD26 and other SARS-CoV-2 associated molecules in human tissues and immune cells in health and disease
Radzikowska, U.; Ding, M.; Tan, G.; Zhakparov, D.; Peng, Y.; Wawrzyniak, P.; Wang, M.; Li, S.; Morita, H.; Altunbulakli, C.; Reiger, M.; Neumann, A. U.; Lunjani, N.; Traidl-Hoffmann, C.; Nadeau, K.; O'Mahony, L.; Akdis, C. A.; Sokolowska, M.
10.1101/2020.05.14.090332 — immunology — Posted on 2020-05-15
2634 Multiple domains in ARHGAP36 regulate PKA degradation and Gli activation
Nano, P. R.; Kudo, T.; Mooney, N. A.; Ni, J.; Demeter, J.; Jackson, P. K.; Chen, J. K.
10.1101/2020.05.14.094961 — cell biology — Posted on 2020-05-15
2635 Non-canonical autophagy drives alternative ATG8 conjugation to phosphatidylserine
Durgan, J.; Lystad, A. H.; Sloan, K.; Carlsson, S. R.; Wilson, M. I.; Marcassa, E.; Ulferts, R.; Webster, J.; Lopez-Clavijo, A. F.; Wakelam, M. J.; Beale, R.; Simonsen, A.; Oxley, D.; Florey, O.
10.1101/2020.05.14.096115 — cell biology — Posted on 2020-05-15
2636 The plate-to-rod transition in trabecular bone loss is elusive
Felder, A.; Monzem, S.; De Souza, R.; Mills, D.; Boyde, A.; Doube, M.
10.1101/2020.05.14.081042 — physiology — Posted on 2020-05-15
2637 Pre-existing and de novo humoral immunity to SARS-CoV-2 in humans
Ng, K.; Faulkner, N.; Cornish, G.; Rosa, A.; Earl, C.; Wrobel, A.; Benton, D.; Roustan, C.; Bolland, W.; Thompson, R.; Agua-Doce, A.; Hobson, P.; Heaney, J.; Rickman, H.; Paraskevopoulou, S.; Houlihan, C. F.; Thomson, K.; Sanchez, E.; Shin, G. Y.; Spyer, M. J.; Walker, P. A.; Kjaer, S.; Riddell, A.; Beale, R.; Swanton, C.; Gandhi, S.; Stockinger, B.; Gamblin, S.; McCoy, L. E.; Cherepanov, P.; Nastouli, E.; Kassiotis, G.
10.1101/2020.05.14.095414 — immunology — Posted on 2020-05-15
2638 Need for speed: Examining protein behaviour during cryoEM grid preparation at different timescales
Klebl, D. P.; Gravett, M. S. C.; Kontziampasis, D.; Wright, D. J.; Bon, R. S.; Monteiro, D.; Trebbin, M.; Sobott, F.; White, H. D.; Darrow, M.; Thompson, R. F.; muench, s. P.
10.1101/2020.05.14.095372 — biochemistry — Posted on 2020-05-15
2640 Phagosome resolution regenerates lysosomes and maintains the degradative capacity in phagocytes
Lancaster, C.; Fountain, A.; Somerville, E.; Sheth, J.; Dayam, R.; Jacobelli, V.; Somerville, A.; Terebiznik, M.; Botelho, R. J.
10.1101/2020.05.14.094722 — cell biology — Posted on 2020-05-15
2641 Endogenous formaldehyde scavenges cellular glutathione resulting in cytotoxic redox disruption
Umansky, C.; Morellato, A.; Scheidegger, M.; Rieckher, M.; Martinefski, M. R.; Fernandez, G. A.; Kolesnikova, K.; Vesting, A. J.; Karakasilioti, I.; Reingruber, H.; Wei, Y.; He, R.; Bollini, M.; Monge, M. E.; Schumacher, B.; Pontel, L. B.
10.1101/2020.05.14.090738 — cell biology — Posted on 2020-05-15
2642 SCA-1 micro-heterogeneity in the fate decision of dystrophic fibro/adipogenic progenitors
Giuliani, G.; Vumbaca, S.; Fuoco, C.; Gargioli, C.; Giorda, E.; Massacci, G.; Palma, A.; Riccio, F.; Vinci, M.; Castagnoli, L.; Cesareni, G.
10.1101/2020.05.14.096438 — cell biology — Posted on 2020-05-15
2644 CoV-AbDab: the Coronavirus Antibody Database
Raybould, M. I. J.; Kovaltsuk, A.; Marks, C.; Deane, C. M.
10.1101/2020.05.15.077313 — immunology — Posted on 2020-05-15
2648 HBV pgRNA can generate a circRNA with two junction sites
Zhu, M.; Liang, Z.; Pan, J.; Hu, X.; Zhang, X.; Xue, R.; Cao, G.; Gong, C.
10.1101/2020.05.14.095273 — molecular biology — Posted on 2020-05-15
2650 IgA MAb blocks SARS-CoV-2 Spike-ACE2 interaction providing mucosal immunity
Ejemel, M.; Li, Q.; Hou, S.; Schiller, Z. A.; Wallace, A. L.; Amcheslavsky, A.; Kurt Yilmaz, N.; Toomey, J. R.; Schneider, R.; Close, B. J.; Chen, D.-Y.; Conway, H. L.; Saeed, M.; Cavacini, L. A.; Klempner, M. S.; Schiffer, C. A.; Wang, Y.
10.1101/2020.05.15.096719 — microbiology — Posted on 2020-05-15
2652 Cingulin unfolds ZO-1 and organizes myosin-2B and gamma-actin to mechanoregulate apical and tight junction membranes
Vasileva, E.; Rouaud, F.; Spadaro, D.; Huang, W.; Colom, A.; Flinois, A.; Shah, J.; Dugina, V.; Chaponnier, C.; Sluysmans, S.; Mean, I.; Jond, L.; Roux, A.; Yan, J.; Citi, S.
10.1101/2020.05.14.095364 — cell biology — Posted on 2020-05-15
2653 Stress-induced translation inhibition through rapid displacement of scanning initiation factors
Bresson, S.; Shchepachev, V.; Spanos, C. S.; Turowski, T.; Rappsilber, J.; Tollervey, D.
10.1101/2020.05.14.096354 — cell biology — Posted on 2020-05-15
2657 Supramammillary neurons projecting to the septum regulate dopamine and motivation for environmental interaction
Kesner, A. J.; Shin, R.; Calva, C. B.; Don, R. F.; Junn, S.; Potter, C. T.; Ramsey, L. A.; Abou-Elnaga, A. F.; Cover, C. G.; Wang, D. V.; Lu, H.; Yang, Y.; Ikemoto, S.
10.1101/2020.05.15.097857 — neuroscience — Posted on 2020-05-15
2660 Altered oligodendroglia and astroglia in chronic traumatic encephalopathy
Chancellor, K. B.; Chancellor, S. E.; Duke-Cohan, J. E.; Huber, B. R.; Stein, T. D.; Alvarez, V. E.; McKee, A. C.
10.1101/2020.05.13.089086 — genomics — Posted on 2020-05-15
2661 Phylogenetic Analysis of SARS-CoV-2 Genomes in Turkey
Adebali, O.; Bircan, A.; Circi, D.; Islek, B.; Kilinc, Z.; Selcuk, B.; Turhan, B.
10.1101/2020.05.15.095794 — genomics — Posted on 2020-05-15
2671 Convergent Antibody Responses to SARS-CoV-2 Infection in Convalescent Individuals
Robbiani, D. F.; Gaebler, C.; Muecksch, F.; Cetrulo Lorenzi, J.; Wang, Z.; Cho, A.; Agudelo, M.; Barnes, C.; Finkin, S.; Hagglof, T.; Oliveira, T.; Viant, C.; Hurley, A.; Millard, K.; Kost, R.; Cipolla, M.; Gazumyan, A.; Gordon, K.; Bianchini, F.; Chen, S.; Ramos, V.; Patel, R.; Dizon, J.; Shimeliovich, I.; Mendoza, P.; Hartweger, H.; Nogueira, L.; Pack, M.; Horowitz, J.; Schmidt, F.; Weisblum, Y.; Hoffmann, H.-H.; Michailidis, E.; Ashbrook, A.; Waltari, E. F.; Pak, J.; Huey-Tubman, K.; Koranda, N.; Hoffman, P.; West, A.; Rice, C.; Hatziioannou, T.; Bjorkman, P.; Bieniasz, P.; Caskey, M.; Nuss
10.1101/2020.05.13.092619 — immunology — Posted on 2020-05-15
2672 Interpretable deep learning of label-free live cell images uncovers functional hallmarks of highly-metastatic melanoma
Zaritsky, A.; Jamieson, A. R.; Welf, E. S.; Nevarez, A.; Cillay, J.; Eskiocak, U.; Cantarel, B. L.; Danuser, G.
10.1101/2020.05.15.096628 — cell biology — Posted on 2020-05-15
2676 Metabolite profiling of experimental cutaneous leishmaniasis lesions demonstrates significant perturbations in tissue phospholipids
McCall, L.-I.; Parab, A.; McKerrow, J.; Dorrestein, P. C.; Thomas, D.; Lostracco-Johnson, S.; de Siquiera-Neto, J. L.
10.1101/2020.05.13.094649 — biochemistry — Posted on 2020-05-15
2677 Revisiting neoantigen depletion signal in the untreated cancer genome
Wang, S.; Wang, X.; Wu, T.; He, Z.; Li, H.; Sun, X.; Liu, X.-S.
10.1101/2020.05.11.089540 — genomics — Posted on 2020-05-15
2680 A mechanistic model of the neural entropy increaseelicited by psychedelic drugs
Herzog, R.; Mediano, P. A. M.; Rosas, F. E.; Carhart-Harris, R.; Sanz, Y.; Tagliazucchi, E.; Cofre, R.
10.1101/2020.05.13.093732 — neuroscience — Posted on 2020-05-15
2681 A Chemical-genetics and Nanoparticle Enabled Approach for in vivo Protein Kinase Analysis
Chen, F.; Liu, Q.; Hilliard, T.; Wang, T.; Liang, H.; Gao, W.; Huang, L.; Wang, D.
10.1101/2020.05.13.094573 — cell biology — Posted on 2020-05-15
2683 A combination of two small molecule toxin inhibitors provides pancontinental preclinical efficacy against viper snakebite
Albulescu, L.-O.; Xie, C.; Ainsworth, S.; Alsolaiss, J.; Crittenden, E.; Dawson, C. A.; Softley, R.; Bartlett, K. E.; Harrison, R. A.; Kool, J.; Casewell, N. R.
10.1101/2020.05.13.094599 — pharmacology and toxicology — Posted on 2020-05-15
2689 β-catenin perturbations control differentiation programs in mouse embryonic stem cells
Pedone, E.; Failli, M.; Gambardella, G.; De Cegli, R.; di Bernardo, D.; Marucci, L.
10.1101/2020.05.15.098137 — cell biology — Posted on 2020-05-15
2691 Indoleamine 2,3-dioxygenase-1 expressing aggregate bone marrow dendritic cell populations are associated with systemic T cell compartment changes in chronic myelomonocytic leukemia
Mangaonkar, A.; Reichard, K. K.; Binder, M.; Coltro, G.; Lasho, T. L.; Carr, R. M.; Chiu, A.; Negron, V.; Hefazi, M.; Anagnostou, T.; Villasboas, J. C.; Gonsalves, W.; Gangat, N.; Shah, M.; Alkhateeb, H. B.; Al-Kali, A.; Elliott, M. A.; Begna, K. H.; Wolanskyj-Spinner, A. P.; Litzow, M. R.; Hogan, W. J.; Ansell, S. M.; Pardanani, A.; Tefferi, A.; Patnaik, M. M.
10.1101/2020.05.14.096297 — immunology — Posted on 2020-05-15
2692 Integrin αvβ8 on T cells is responsible for suppression of anti-tumor immunity in multiple syngeneic models and is a promising target for tumor immunotherapy
Dodagatta-Marri, E.; Ma, H.-Y.; Liang, B.; Li, J.; Meyer, D. S.; Sun, K.-H.; Ren, X.; Zirak, B.; Rosenblum, M. D.; Headley, M.; Pinzas, L.; Reed, N. I.; Del Cid, J. S.; Adoumie, M.; Hann, B. C.; Yang, S.; Giddabasappa, A.; Noorbehesht, K.; Yang, B.; Dal Porto, J.; Tsukui, T.; Niessen, K.; Atakilit, A.; Akhurst, R. J.; Sheppard, D.
10.1101/2020.05.14.084913 — cancer biology — Posted on 2020-05-15
2694 Compact and contactless reflectance confocal microscope for neurosurgery
Cui, J.; Turcotte, R.; Hampson, K. M.; Wincott, M.; Schmidt, C. C.; Emptage, N. J.; Charalampaki, C.; Booth, M. J.
10.1101/2020.05.13.093435 — neuroscience — Posted on 2020-05-15
2696 Pattern Separation Contributes to Categorical Face Perception
Baker, S. W.; Youm, A.; Levy, Y.; Moscovitch, M.; Rosenbaum, R. S.
10.1101/2020.05.13.094276 — neuroscience — Posted on 2020-05-15
2697 Dose-dependent and disease-modifying effects of striatal infusion of cholesterol in Huntington's disease
Birolini, G.; Valenza, M.; DiPaolo, E.; Vezzoli, E.; Talpo, F.; Maniezzi, C.; Caccia, C.; Leoni, V.; Bocchi, V. D.; Conforti, P.; Sogne, E.; Petricca, L.; Cariulo, C.; Verani, M.; Caricasole, A.; Falqui, A.; Biella, G.; Cattaneo, E.
10.1101/2020.05.13.092742 — neuroscience — Posted on 2020-05-15
2698 Expansion Sequencing: Spatially Precise In Situ Transcriptomics in Intact Biological Systems
Alon, S.; Goodwin, D.; Sinha, A.; Wassie, A.; Chen, F.; Daugharthy, E.; Bando, Y.; Kajita, A.; Xue, A.; Marrett, K.; Prior, R.; Cui, Y.; Payne, A.; Yao, C.-C.; Suk, H.-J.; Wang, R.; Yu, C.-C.; Tillberg, P.; Reginato, P.; Pak, N.; Liu, S.; Punthambaker, S.; Iyer, E.; Kohman, R.; Miller, J.; Lein, E.; Lako, A.; Cullen, N.; Rodig, S.; Helvie, K.; Abravanel, D.; Wagle, N.; Johnson, B.; Klughammer, J.; Slyper, M.; Waldman, J.; Jane-Valbuena, J.; Rozenblatt-Rosen, O.; Regev, A.; Church, G.; Marblestone, A.; Boyden, E. S.
10.1101/2020.05.13.094268 — genomics — Posted on 2020-05-15
2700 Cell fate coordinates mechano-osmotic forces in intestinal crypt morphogenesis
Yang, Q.; Xue, S.-L.; Chan, C. J.; Rempfler, M.; Vischi, D.; Mauer Gutierrez, F.; Hiiragi, T.; Hannezo, E.; Liberali, P.
10.1101/2020.05.13.094359 — developmental biology — Posted on 2020-05-15
2705 Cellular taxonomy and spatial organization of the ventral posterior hypothalamus reveals neuroanatomical parcellation of the mammillary bodies
Mickelsen, L. E.; Flynn, W. F.; Springer, K.; Wilson, L.; Beltrami, E. J.; Bolisetty, M.; Robson, P. F.; Jackson, A. C.
10.1101/2020.05.14.096818 — neuroscience — Posted on 2020-05-15
2708 High-Resolution Linkage Map and QTL Analyses for Machine Harvest Traits in Autotetraploid Blueberry
Cappai, F.; Amadeu, R. R.; Benevenuto, J.; Cullen, R.; Grossman, A.; Ferrao, L. F. V.; Munoz, P. R.
10.1101/2020.05.13.093633 — genomics — Posted on 2020-05-15
2712 Unraveling the interaction between doxorubicin and DNA origami nanostructures for customizable chemotherapeutic drug release
Ijäs, H.; Shen, B.; Heuer-Jungemann, A.; Keller, A.; Kostiainen, M. A.; Liedl, T.; Ihalainen, J. A.; Linko, V.
10.1101/2020.05.13.088054 — biochemistry — Posted on 2020-05-15
2713 Transcription Co-Factor LBH Is Necessary for Maintenance of Stereocilia Bundles and Survival of Cochlear Hair Cells
Liu, H.; Giffen, K. P.; Grati, M.; Morrill, S.; Li, Y.; Liu, X. Z.; Briegel, K. J.; He, D. Z. Z.
10.1101/2020.05.13.093377 — neuroscience — Posted on 2020-05-15
2715 Microtubule re-organization during female meiosis in C. elegans
Lantzsch, I.; Yu, C.-H.; Yazdhkasti, H.; Lindow, N.; Szentgyoergyi, E.; Prohaska, S.; Srayko, M.; Fuerthauer, S.; Redemann, S.
10.1101/2020.05.14.095984 — cell biology — Posted on 2020-05-15
2716 On the correlation between material-induced cell shape and phenotypical response of human mesenchymal stem cells
Vasilevich, A. S.; Vermeulen, S. S.; Kamphuis, M.; Roumans, N.; Eroume, S.; Hebels, D. G. A. J.; Peppel, J. v. d.; Reihs, R.; Beijer, N. R. M.; Carlier, A.; Carpenter, A. E.; Singh, S.; de Boer, J.
10.1101/2020.05.13.093641 — bioinformatics — Posted on 2020-05-15
2718 MET Receptor Tyrosine Kinase Regulates Vagal Laryngeal Motor Neuron Development and Lifespan Ultrasonic Vocal Communication
Kamitakahara, A. K.; Ali Marandi Ghoddousi, R.; Lanjewar, A. L.; Magalong, V. M.; Wu, H.-H.; Levitt, P.
10.1101/2020.05.13.093617 — neuroscience — Posted on 2020-05-15
2719 Depth relationships and measures of tissue thickness in dorsal midbrain
Truong, P.; Kim, J. H.; Savjani, R.; Sitek, K. R.; Hagberg, G.; Scheffler, K.; Ress, D.
10.1101/2020.05.13.093492 — neuroscience — Posted on 2020-05-15
2720 BLM-dependent Break-Induced Replication handles DSBs in transcribed chromatin upon impaired RNA:DNA hybrids dissolution.
Cohen, S.; Guenole, A.; Marnef, A.; Clouaire, T.; Puget, N.; Rocher, V.; Arnould, C.; Aguirrebengoa, M.; Genais, M.; Verneka, D.; Mourad, R.; Borde, V.; Legube, G.
10.1101/2020.05.13.093112 — molecular biology — Posted on 2020-05-15
2722 Satellite cell expansion is mediated by P-eIF2α dependent Tacc3 translation
Fujita, R.; Lean, G.; Jamet, S.; Hebert, S.; Kleinman, C. L.; Crist, C.
10.1101/2020.05.13.093302 — cell biology — Posted on 2020-05-15
2724 Supersampling Enables Accurate Microstructural Bone Adaptation Simulations in Human in vivo HR-pQCT Images
Ohs, N.; Tourolle ne Betts, D. C.; Atkins, P. R.; Sebastian, S.; van Rietbergen, B.; Blauth, M.; Christen, P.; Müller, R.
10.1101/2020.05.13.093328 — bioinformatics — Posted on 2020-05-15
2725 NDI: A platform-independent data interface and database for neuroscience physiology and imaging experiments
Garcia Murillo, D.; Rogovin, O.; Zhao, Y.; Chen, S.; Wang, Z.; Papaemmanouil, O.; Van Hooser, S. D.
10.1101/2020.05.13.093542 — neuroscience — Posted on 2020-05-15
2731 Structure-function properties in disordered condensates
Bhandari, K.; Cotten, M. A.; Kim, J.; Rosen, M. K.; Schmit, J. D.
10.1101/2020.05.14.096388 — biophysics — Posted on 2020-05-15
2733 An RNA dynamic ensemble at atomic resolution
Shi, H.; Rangadurai, A.; Abou Assi, H.; Roy, R.; Case, D. A.; Herschlag, D.; Yesselman, J. D.; Al-Hashimi, H. M.
10.1101/2020.05.13.092981 — biophysics — Posted on 2020-05-15
2734 An NMR-based biosensor to measure stereo-specific methionine sulfoxide reductase (MSR) activities in vitro and in vivo.
Sanchez-Lopez, M. C.; Labadie, N.; Lombardo, V. A.; Biglione, F. A.; Manta, B.; Jacob, R. S.; Gladyshev, V. N.; Abdelilah-Seyfried, S.; Selenko, P.; Binolfi, A.
10.1101/2020.05.14.092957 — biophysics — Posted on 2020-05-15
2741 The Ice Nucleating Protein InaZ is Activated by Low Temperature
Roeters, S. J.; Golbek, T. W.; Bregnhoj, M.; Drace, T.; Alamdari, S.; Roseboom, W.; Kramer, G.; Santl-Temkiv, T.; Finster, K.; Woutersen, S.; Pfaendtner, J.; Boesen, T.; Weidner, T.
10.1101/2020.05.15.092684 — biophysics — Posted on 2020-05-15
2751 Shifts from pulled to pushed range expansions caused by reductions in connectedness
Dahirel, M.; Bertin, A.; Haond, M.; Blin, A.; Lombaert, E.; Calcagno, V.; Fellous, S.; Mailleret, L.; Vercken, E.
10.1101/2020.05.13.092775 — ecology — Posted on 2020-05-15
2752 Phenotyping Root Architecture of Soil-Grown Rice: A Robust Protocol Combining Manual Practices with Image-based Analyses.
De Bauw, P.; Ramarolahy, J. A.; Senthilkumar, K.; Rakotoson, T.; Merckx, R.; Smolders, E.; Van Houtvinck, R.; Vandamme, E.
10.1101/2020.05.13.088369 — developmental biology — Posted on 2020-05-15
2755 A novel RNA virus, Macrobrachium rosenbergii Golda virus (MrGV), linked to mass mortalities of the larval giant freshwater prawn in Bangladesh
Hooper, C.; Debnath, P. P.; Biswas, S.; van Aerle, R.; Bateman, K. S.; Basak, S. K.; Rahman, M. M.; Mohan, C. V.; Rakibul Islam, H. M.; Ross, S.; Stentiford, G. D.; Currie, D.; Bass, D.
10.1101/2020.05.12.090258 — molecular biology — Posted on 2020-05-15
2756 Synergistic Material-Topography Combinations to Achieve Immunomodulatory Osteogenic Biomaterials
Burroughs, L.; Amer, M.; Vassey, M.; Koch, B.; Figueredo, G.; Mukonoweshuro, B.; Mikulskis, P.; Vasilevich, A.; Vermeulen, S.; Dryden, I. L.; Winkler, D. A.; Ghaemmaghami, A. M.; Rose, F. R. A. J.; de Boer, J.; Alexander, M. R.
10.1101/2020.04.29.067421 — bioengineering — Posted on 2020-05-15
2758 Aberrant PARP1 Activity Couples DNA Breaks to Deregulated Presynaptic Calcium Signalling and Lethal Seizures
Komulainen, E.; Badman, J.; Rey, S.; Rulten, S.; Ju, L.; Fennel, K.; McKinnon, P.; Staras, K.; Caldecott, K.
10.1101/431916 — neuroscience — Posted on 2020-05-15
2759 Stress-primed secretory autophagy drives extracellular BDNF maturation
Martinelli, S.; Anderzhanova, E. A.; Wiechmann, S.; Dethloff, F.; Weckmann, K.; Bajaj, T.; Hartmann, J.; Hafner, K.; Poehlmann, M. L.; Jollans, L.; Maccarrone, G.; Hausch, F.; Turck, C. W.; Philipsen, A.; Schmidt, M. V.; Kuster, B.; Gassen, N. C.
10.1101/2020.05.13.090514 — molecular biology — Posted on 2020-05-15
2760 circZNF827 nucleates a transcription inhibitory complex to balance neuronal differentiation
Hollensen, A. K.; Thomsen, H. S.; Llinares, M. L.; Kamstrup, A. B.; Jensen, J. M.; Luckmann, M.; Birkmose, N.; Palmfeldt, J.; Jensen, T. H.; Hansen, T. B.; Damgaard, C. K.
10.1101/791798 — molecular biology — Posted on 2020-05-15
2761 A novel humanized mouse model to study the function of human cutaneous memory T cells in vivo in human skin
Klicznik, M. M.; Benedetti, A.; Gail, L. M.; Varkhande, S. R.; Holly, R.; Laimer, M.; Stoecklinger, A.; Sir, A.; Reitsamer, R.; Neuper, T.; Horejs-Hoeck, J.; Rosenblum, M. D.; Campbell, D. J.; Murauer, E.; Gratz, I. K.
10.1101/490060 — immunology — Posted on 2020-05-15
2764 Confronting p-hacking: addressing p-value dependence on sample size
Gomez-de-Mariscal, E.; Sneider, A.; Jayatilaka, H.; Phillip, J. M.; Wirtz, D.; Munoz-Barrutia, A.
10.1101/2019.12.17.878405 — bioinformatics — Posted on 2020-05-15
2765 Titration of in-cellula affinities of protein-protein interactions
Cluet, D.; Vergier, B.; Levy, N.-P.; Dehau, L.; Thurman, A.; Amri, I.; Spichty, M.
10.1101/2020.04.27.063552 — biochemistry — Posted on 2020-05-15
2766 An adaptive pre-DNA-damage-response protects genome integrity
Ragu, S.; Matos-Rodrigues, G.; Droin, N.; Barascu, A.; Caillat, S.; Zarkovic, G.; Siberchicot, C.; Dardillac, E.; Gelot, C.; Radicella, J. P.; Ishchenko, A. A.; Ravanat, J.-L.; Solary, E.; Lopez, B. S.
10.1101/2020.05.13.092460 — cell biology — Posted on 2020-05-15
2768 RBFOX2 Is Critical For Maintaining Alternative Polyadenylation And Mitochondrial Health In Myoblasts
Kuyumcu-Martinez, M. N.; Routh, A. L.; Cao, J.; Jaworski, E.; Rayavara, K.; Belanger, K.; Sooter, A.; Miller, S.; Verma, S. K.; Ji, P.; Elrod, N.; Wagner, E. J.; Popov, V.; Garg, N. J.
10.1101/2020.05.13.093013 — molecular biology — Posted on 2020-05-15
2770 Kidney single-cell atlas reveals myeloid heterogeneity in progression and regression of kidney disease.
Conway, B. R.; O'Sullivan, E. D.; Cairns, C.; O'Sullivan, J.; Simpson, D. J.; Salzano, A.; Connor, K.; Ding, P.; Humphries, D.; Stewart, K.; Teenan, O.; Henderson, N. C.; Benezech, C.; Ramachandran, P.; Ferenbach, D.; Hughes, J.; Chandra, T.; Denby, L.
10.1101/2020.05.14.095166 — immunology — Posted on 2020-05-15
2773 dms-view: Interactive visualization tool for deep mutational scanning data
Hilton, S. K.; Huddleston, J. L.; Black, A.; North, K.; Dingens, A. S.; Bedford, T.; Bloom, J. D.
10.1101/2020.05.14.096842 — bioinformatics — Posted on 2020-05-15
2775 A Molecular Mechanism for Probabilistic Bet-hedging and its Role in Viral Latency
Chaturvedi, S.; Klein, J.; Vardi, N.; Bolovan-Fritts, C.; Wolf, M.; Du, K.; Mlera, L.; Calvert, M.; Moorman, N. J.; Goodrum, F.; Huang, B.; Weinberger, L. S.
10.1101/2020.05.14.096560 — molecular biology — Posted on 2020-05-15
2776 Plasticity of the xylem vulnerability to embolism in poplar relies on quantitative pit properties rather than on pit structure
Lemaire, C.; Quilichini, Y.; Brunel-Michac, N.; Santini, J.; Berti, L.; Cartailler, J.; Conchon, P.; Badel, E.; Herbette, S.
10.1101/2020.05.14.096222 — plant biology — Posted on 2020-05-15
2778 Huge and variable diversity of episymbiotic CPR bacteria and DPANN archaea in groundwater ecosystems
He, C. Y.; Keren, R.; Whittaker, M.; Farag, I. F.; Doudna, J. A.; Cate, J. H.; Banfield, J. F.
10.1101/2020.05.14.094862 — microbiology — Posted on 2020-05-15
2779 Conserved anti-inflammatory effects and sensing of butyrate in zebrafish
Cholan, P. M.; Han, A.; Woodie, B. R.; Kurz, A. R.; Britton, W. J.; Ye, L.; Holmes, Z. C.; McCann, J. R.; David, L. A.; Rawls, J. F.; Oehlers, S. H.
10.1101/2020.05.13.069997 — immunology — Posted on 2020-05-15
2782 Psi promotes Drosophila wing growth through transcriptional repression of key developmental networks
Zaytseva, O.; Mitchell, N. C.; Delandre, C.; Nie, Z.; Evers, M.; Werner, J. K.; Lis, J. T.; Hannan, R. D.; Levens, D. L.; Marshall, O. J.; Quinn, L. M.
10.1101/2020.05.13.094664 — developmental biology — Posted on 2020-05-15
2783 Exploring phenotyping plasticity for improving deficit irrigation and growth performance in maize
Urfan, M.; Hakla, H. R.; Sharma, S.; Sharma, M.; Khajuria, M.; Satbhai, S. B.; Vyas, D.; Bhougal, S.; Pal, S.
10.1101/2020.05.12.087940 — plant biology — Posted on 2020-05-15
2785 A role for glutathione in buffering excess intracellular copper in Streptococcus pyogenes
Stewart, L. J.; Ong, C.-l. Y.; Zhang, M. M.; Brouwer, S.; McIntyre, L.; Davies, M. R.; Walker, M. J.; McEwan, A. G.; Waldron, K. J.; Djoko, K. Y.
10.1101/2020.05.14.095349 — microbiology — Posted on 2020-05-15
2786 Meanders as a scaling motif for understanding of floodplain soil microbiome and biogeochemical potential at the watershed scale
Matheus Carnevali, P. B.; Lavy, A.; Thomas, A. D.; Crits-Christoph, A.; Diamond, S.; Meeheust, R.; Olm, M. R.; Sharrar, A.; Lei, S.; Dong, W.; Falco, N.; Bouskill, N.; Newcomer, M.; Nico, P.; Wainwright, H.; Dwivedi, D.; Williams, K. H.; Hubbard, S.; Banfield, J. F.
10.1101/2020.05.14.086363 — microbiology — Posted on 2020-05-15
2787 Structural insights into loss of function of a pore forming toxin and its role in pneumococcal adaptation to an intracellular lifestyle
Badgujar, D. C.; Anil, A.; Green, A. E.; Surve, M. V.; Madhavan, S.; Beckett, A.; Prior, I.; Godsora, B. K.; Patil, S. B.; More, P. K.; Guha Sarkar, S.; Mitchell, A.; Banerjee, R.; Phale, P. P.; Mitchell, T. J.; Neill, D. R.; Bhaumik, P.; Banerjee, A.
10.1101/2020.05.13.093682 — microbiology — Posted on 2020-05-15
2789 Monocytes mediate Salmonella Typhimurium-induced tumour growth inhibition
Johnson, S.; Ormsby, M. J.; Wessel, H. M.; Hulme, H.; Bravo Blas, A.; McIntosh, A.; Mason, S.; Coffelt, S. B.; Tait, S. W.; Mowat, A. M.; Milling, S.; Blyth, K.; Wall, D. M.
10.1101/2020.05.13.092858 — immunology — Posted on 2020-05-15
2790 ZEB1 is Required for NHEJ-Mediated DSB Repair in Euchromatin
Genetta, T. L.; Abbas, T.; Pandita, R.; Hunt, C. R.; Pandita, T.; Larner, J. M.
10.1101/2020.05.13.094391 — cancer biology — Posted on 2020-05-15
2794 Human Dicer helicase domain acts as an interaction platform to recruit PKR and dsRNA binding proteins during viral infection
Montavon, T. C.; Lefevre, M.; Baldaccini, M.; Girardi, E.; Chane-Woon-Ming, B.; Messmer, M.; Hammann, P.; Chicher, J.; Pfeffer, S.
10.1101/2020.05.14.095356 — microbiology — Posted on 2020-05-15
2795 A druggable oxidative folding pathway in the endoplasmic reticulum of human malaria parasites
Cobb, D. W.; Kudyba, H. M.; Villegas, A.; Hoopmann, M. R.; Baptista, R.; Bruton, B.; Krakowiak, M.; Moritz, R. L.; Muralidharan, V.
10.1101/2020.05.13.093591 — microbiology — Posted on 2020-05-15
2796 Anaplerotic pathways in Halomonas elongata: the role of the sodium gradient
Hobmeier, K.; Goëss, M.; Sehr, C.; Kunte, H. J.; Kremling, A.; Pfluger-Grau, K.; Marin-Sanguino, A.
10.1101/2020.05.13.093179 — microbiology — Posted on 2020-05-15
2798 SLE non-coding Genetic Risk Variant Determines the Epigenetic Dysfunction of an Immune Cell Specific Enhancer that Controls Disease-critical microRNA Expression
Hou, G.; Harley, I. T. W.; Lu, X.; Zhou, T.; Xu, N.; Yao, C.; Qin, Y.; Ouyang, Y.; Ma, J.; Zhu, X.; Yu, X.; Dai, D.; Xu, H.; Ding, H.; Tang, Y.; Namjou, B.; Weirauch, M. T.; Kottyan, L. C.; Harley, J. B.; Shen, N.
10.1101/2020.05.13.092932 — genetics — Posted on 2020-05-15
2799 Unveiling diffusion pattern and structural impact of the most invasive SARS-CoV-2 spike mutation
Trucchi, E.; Gratton, P.; Mafessoni, F.; Motta, S.; Cicconardi, F.; Bertorelle, G.; D'Annessa, I.; Di Marino, D.
10.1101/2020.05.14.095620 — evolutionary biology — Posted on 2020-05-15
2800 Geographic and environmental contributions to genomic divergence in mangrove forests
Silva, M. F. d.; Cruz, M. V.; Junior, J. d. D. V.; Zucchi, M. I.; Mori, G. M.; de Souza, A. P.
10.1101/2020.01.08.889717 — evolutionary biology — Posted on 2020-05-15
2803 Streptomyces endophytes promote the growth of Arabidopsis thaliana
Worsley, S. F.; Newitt, J. T.; Rassbach, J.; Batey, S. F. D.; Holmes, N. A.; Murrell, C.; Wilkinson, B.; Hutchings, M. I.
10.1101/532309 — microbiology — Posted on 2020-05-15
2804 Toxoplasma TgATG9 is critical for autophagy and long-term persistence in tissue cysts
Smith, D.; Kannan, G.; Coppens, I.; Wang, F.; Nugyen, H. M.; Cerutti, A.; Schultz, T. L. B.; Rimple, P.; Di Cristina, M.; Besteiro, S.; Carruthers, V. B.
10.1101/2020.05.13.093401 — microbiology — Posted on 2020-05-15
2805 Deciphering a marine bone degrading microbiome reveals a complex community effort
Borchert, E.; Garcia-Moyano, A.; Sanchez-Carrillo, S.; Dahlgren, T. G.; Slaby, B.; Bjerga, G. E. K.; Ferrer, M.; Franzenburg, S.; Hentschel, U.
10.1101/2020.05.13.093005 — microbiology — Posted on 2020-05-15
2806 Predicting the Immunogenicity of T cell epitopes: From HIV to SARS-CoV-2
Gao, A.; Chen, Z.; Segal, F. P.; Mary Carrington, M.; Streeck, H.; Chakraborty, A. K.; Juelg, B.
10.1101/2020.05.14.095885 — immunology — Posted on 2020-05-15
2809 GATA3 controls mitochondrial biogenesis in primary human CD4+ T cells during DNA damage
Callender, L. A.; Schroth, J.; Carroll, E. C.; Romano, L. E. L.; Hendy, E.; Kelly, A.; Lavender, P.; Akbar, A. N.; Chapple, J. P.; Henson, S. M.
10.1101/727479 — immunology — Posted on 2020-05-15
2810 Reduced transfer coefficient of carbon monoxide in pulmonary arterial hypertension implicates rare protein-truncating variants in KDR
Swietlik, E. M.; Greene, D.; Zhu, N.; Megy, K.; Cogliano, M.; Rajaram, S.; Pandya, D.; Tilly, T.; Lutz, K. A.; Welch, C. C. L.; Pauciulo, M. W.; Southgate, L.; Martin, J. M.; Treacy, C. M.; Penkett, C. J.; Stephens, J. C.; UK National Cohort Study of Idiopathic and Heritable PAH, ; NIHR Bioresource for Translational Research - Rare Diseases, ; US PAH Biobank Enrolling Centers' Investigators, ; Lawrie, A.; Wilkins, M. R.; Trembath, R. C.; Shen, Y.; Wendy, C. K.; Swift, A. J.; Nichols, W. C.; Morrell, N. W.; Gräf, S.
10.1101/2019.12.11.871210 — genetics — Posted on 2020-05-15
2814 LIVE-PAINT: Super-Resolution Microscopy Inside Live Cells Using Reversible Peptide-Protein Interactions
Oi, C.; Gidden, Z.; Holyoake, L. V.; Kantelberg, O.; Mochrie, S.; Horrocks, M. H.; Regan, L.
10.1101/2020.02.03.932228 — synthetic biology — Posted on 2020-05-15
2815 Testing relationships between multimodal modes of brain structural variation and age, sex and polygenic scores for neuroticism in children and adolescents
Norbom, L. B.; Rokicki, J.; van der Meer, D.; Alnaes, D.; Doan, N. T.; Moberget, T.; Kaufmann, T.; Andreassen, O.; Westlye, L. T.; Tamnes, C. K.
10.1101/2019.12.20.883959 — neuroscience — Posted on 2020-05-15
2818 A cyclin-dependent kinase 5-derived peptide inhibits Cdk5/p25 activity and improves neurodegenerative phenotypes
Seo, J.; Pao, P.-C.; Kritskiy, O.; Lee, A.; Patnaik, D.; Watson, L. A.; Bula, M.; Barker, S. J.; Penney, J.; Silva, M. C.; Haggarty, S. J.; Tsai, L.-H.
10.1101/2020.05.12.090472 — neuroscience — Posted on 2020-05-15
2819 Effect of allelopathy on plant performance
Zhang, Z.; Liu, Y.; Yuan, L.; Weber, E.; van Kleunen, M.
10.1101/2020.05.14.095190 — ecology — Posted on 2020-05-14
2820 Size-dependent patterns of cell proliferation and migration in freely-expanding epithelia
Heinrich, M. A.; Alert, R.; LaChance, J.; Zajdel, T. J.; Kosmrlj, A.; Cohen, D. J.
10.1101/2020.02.28.970418 — cell biology — Posted on 2020-05-14
2821 annoFuse: an R Package to annotate and prioritize putative oncogenic RNA fusions
Gaonkar, K. S.; Rathi, K. S.; Jain, P.; Zhu, Y.; Chimicles, N. A.; Brown, M. A.; Naqvi, A. S.; Zhang, B.; Storm, P. B.; Maris, J. M.; Resnick, A. C.; Raman, P.; Taroni, J. N.; Rokita, J. L.
10.1101/839738 — bioinformatics — Posted on 2020-05-14
2825 Tracing the in vivo fate of nanoparticles with a "non-self" biological identity
Mohammad-Beigi, H.; Scavenius, C.; Jensen, P. B.; Kjaer-Sorensen, K.; Oxvig, C.; Boesen, T.; Enghild, J. J.; Sutherland, D. S.; Hayashi, Y.
10.1101/2020.03.27.012146 — pharmacology and toxicology — Posted on 2020-05-14
2827 Reduced Auditory Steady State Responses in Autism Spectrum Disorder
Seymour, R. A.; Rippon, G.; Gooding-Williams, G.; Sowman, P. F.; Kessler, K.
10.1101/837633 — neuroscience — Posted on 2020-05-14
2830 Crystal structures of SARS-CoV-2 ADP-ribose phosphatase (ADRP): from the apo form to ligand complexes
Michalska, K.; Kim, Y.; Jedrzejczak, R.; Maltseva, N. I.; Stols, L.; Endres, M.; Joachimiak, A.
10.1101/2020.05.14.096081 — molecular biology — Posted on 2020-05-14
2831 Characteristic and quantifiable COVID-19-like abnormalities in CT- and PET/CT-imaged lungs of SARS-CoV-2-infected crab-eating macaques (Macaca fascicularis)
Finch, C. L.; Crozier, I.; Lee, J. H.; Byrum, R.; Cooper, T. K.; Liang, J.; Sharer, K.; Solomon, J.; Sayre, P. J.; Kocher, G.; Bartos, C.; Aiosa, N. M.; Castro, M.; Larson, P. A.; Adams, R.; Beitzel, B.; Di Paola, N.; Kugelman, J. R.; Kurtz, J. R.; Burdette, T.; Nason, M. C.; Feuerstein, I. M.; Palacios, G.; St. Claire, M. C.; Lackemeyer, M. G.; Johnson, R. F.; Braun, K. M.; Ramuta, M. D.; Wada, J.; Schmaljohn, C. S.; Friedrich, T. C.; O'Connor, D. H.; Kuhn, J. H.
10.1101/2020.05.14.096727 — microbiology — Posted on 2020-05-14
2832 The coding capacity of SARS-CoV-2
Finkel, Y.; Mizrahi, O.; Nachshon, A.; Weingarten-Gabbay, S.; Yahalom-Ronen, Y.; Tamir, H.; Achdout, H.; Melamed, S.; Weiss, S.; Isrealy, T.; Paran, N.; Schwartz, M.; Stern-Ginossar, N.
10.1101/2020.05.07.082909 — microbiology — Posted on 2020-05-14
2835 Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveola formation
Tillu, V.; Rae, J.; Gao, Y.; Ariotti, N.; Floetenmeyer, M.; Kovtun, O.; McMahon, K.-A.; Chaudhary, N.; Parton, R. G.; Collins, B. M.
10.1101/831149 — cell biology — Posted on 2020-05-14
2838 Exosomes Facilitate Transmission of SARS-CoV-2 Genome into Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Kwon, Y.; Nukala, S. B.; Srivastava, S.; Miyamoto, H.; Ismail, N. I.; Ong, S.-B.; Lee, W. H.; Ong, S.-G.
10.1101/2020.05.14.093583 — cell biology — Posted on 2020-05-14
2839 A limbic circuit selectively linking active escape to food suppression
Azevedo, E.; Tan, B.; Pomeranz, L.; Ivan, V.; Fetcho, R.; Schneeberger, M.; Doerig, K.; Liston, C.; Friedman, J.; Stern, S.
10.1101/683946 — neuroscience — Posted on 2020-05-14
2840 Iron Chelator-Mediated Anoxic Biotransformation of Lignin by Novel sp., Tolumonas lignolytica BRL6-1
Chaput, G.; Billings, A. F.; DeDiego, L.; Orellana, R.; Adkins, J. N.; Chu, R.; Simmons, B.; DeAngelis, K. M.
10.1101/2020.05.14.095802 — microbiology — Posted on 2020-05-14
2846 Prevalence of Major Limb Loss (MLL) in Post conflict Acholi sub-region of Northern Uganda: Cross sectional study
Atim, P.; Loum, C. S.; Okello, T. R.; Magada, S. M.; Yagos, W. O.; Abelle, P.; Moro, E. B.; Huck, J.; Redmond, A.; Nirmalan, M.
10.1101/2020.05.14.095836 — pathology — Posted on 2020-05-14
2849 Cerebrospinal fluid endo-lysosomal proteins as potential biomarkers for Huntingtons disease.
Lowe, A.; Sjödin, S.; Rodrigues, F.; Byrne, L.; Blennow, K.; Tortelli, R.; Zetterberg, H.; Wild, E.
10.1101/2020.05.14.095828 — neuroscience — Posted on 2020-05-14
2850 Intracellular Cryptococcus neoformans disrupts the transcriptome profile of M1- and M2-polarized host macrophages
Subramani, A.; Griggs, P.; Frantzen, N.; Mendez, J.; Tucker, J.; Murriel, J.; Sircy, L.; McClelland, E. E.; Seipelt-Thiemann, R. L.; Nelson, D. E.
10.1101/2020.05.14.095752 — immunology — Posted on 2020-05-14
2851 Self-organized map: the new aproach for study of genetic divergence in kale
Brito, O. G.; Andrade Junior, V. C. d.; Azevedo, A. M.; Silva, M. T. N. L.; Sa, L. G. d.; Rodrigues, C. H. O.; Fernandes, A. C. G.
10.1101/2020.05.14.095711 — genetics — Posted on 2020-05-14
2852 Differential Effects of RASA3 Mutations on Hematopoiesis are Profoundly Influenced by Genetic Background and Molecular Variant
Robledo, R. F.; Ciciotte, S. L.; Graber, J. H.; Zhao, Y.; Lambert, A. J.; Gwynn, B.; Maki, N. J.; Blanc, L.; Peters, L.
10.1101/2020.05.14.095745 — genetics — Posted on 2020-05-14
2855 Cobalt(III) Schiff Base complexes stabilize non-fibrillar amyloid-β aggregates with reduced toxicity
Roberts, K. F.; Brue, C.; Preston, A.; Baxter, D.; Herzog, E.; Varelas, E.; Meade, T. J.
10.1101/2020.05.12.091405 — neuroscience — Posted on 2020-05-14
2856 Structure of a proton-powered molecular motor that drives protein transport and gliding motility
Hennell-James, R.; Deme, J.; Kjaer, A.; Alcock, F.; Silale, A.; Lauber, F.; Berks, B.; Lea, S. M.
10.1101/2020.05.11.089193 — biochemistry — Posted on 2020-05-14
2858 Single-cell analysis supports a luminal-neuroendocrine transdifferentiation in human prostate cancer
Dong, B.; Miao, J.; Wang, Y.; Luo, W.; Ji, Z.; Lai, H.; Zhang, M.; Cheng, X.; Wang, J.; Fang, Y.; Zhu, H. H.; Chua, C. W.; Fan, L.; Zhu, Y.; Pan, J.; Wang, J.; Xue, W.; Gao, W. Q.
10.1101/2020.05.12.091132 — cancer biology — Posted on 2020-05-14
2861 Annexin-A1 tripeptide attenuates surgery-induced neuroinflammation and memory deficits through regulation of the NLRP3 inflammasome
Zhang, Z.; Ma, Q.; Velagapudi, R.; Barclay, W. E.; Rodriguiz, R. M.; Wetsel, W. C.; Shinohara, M. L.; Terrando, N.
10.1101/2020.05.12.090654 — neuroscience — Posted on 2020-05-14
2863 Single Trial Decoding of Movement Intentions Using Functional Ultrasound Neuroimaging
Norman, S. L.; Maresca, D.; Christopoulos, V. N.; Griggs, W. S.; Demene, C.; Tanter, M.; Shapiro, M. G.; Andersen, R. A.
10.1101/2020.05.12.086132 — neuroscience — Posted on 2020-05-14
2864 GroEL/ES Buffers Entropic Traps In Folding Pathway During Evolution Of A Model Substrate
Sadat, A.; Tiwari, S.; Verma, K.; Ray, A.; Ali, M.; Upadhyay, V.; Singh, A.; Chaphalkar, A.; Chakraborty, R.; Chakraborty, K.; Mapa, K.
10.1101/2020.05.12.090233 — molecular biology — Posted on 2020-05-14
2871 Seizures are a druggable mechanistic link between TBI and subsequent tauopathy
Alyenbaawi, H.; Kanyo, R.; Locskai, L. F.; Kamali-Jamil, R.; DuVal, M. G.; Bai, Q.; Wille, H.; Burton, E. A.; Allison, W. T.
10.1101/2020.05.12.091819 — neuroscience — Posted on 2020-05-14
2873 TAZ inhibits GR and coordinates hepatic glucose homeostasis in normal physiologic states
Xu, S.; Liu, Y.; Hu, R.; Wang, M.; Stohr, O.; Xiong, Y.; Chen, L.; Kang, H.; Zheng, L.; Cai, S.; He, L.; Wang, C.; Copps, K. D.; White, M.; Miao, J.
10.1101/2020.05.12.091264 — biochemistry — Posted on 2020-05-14
2880 Are mice born normally with an egg-only diet?
Isobe, K.-i.; SAto, N.; Ono, K.; Fujita, H.; kawamura, M.; Sasaki, H.; Yamamoto, S.; Nishio, N.
10.1101/2020.05.12.091660 — developmental biology — Posted on 2020-05-14
2882 The Genomic Landscape of Prostate Cancer Brain Metastases
Rodriguez, A.; Gallon, J.; Akhoundova, D.; Maletti, S.; Ferguson, A.; Cyrta, J.; Amstutz, U.; Garofoli, A.; Paradiso, V.; Tomlins, S.; Hewer, E.; Genitsch, V.; Fleischmann, A.; Rushing, E. J.; Grobholz, R.; Fischer, I.; Jochum, W.; Cathomas, G.; Bubendorf, L.; Moch, H.; Ng, C. K.; Gillessen Sommer, S.; Piscuoglio, S.; Rubin, M. A.
10.1101/2020.05.12.092296 — cancer biology — Posted on 2020-05-14
2883 Exploiting KRAS-driven Ferroaddiction in Cancer Through Ferrous Iron-Activatable Drug Conjugates (FeADC)
Jiang, H.; Muir, R. K.; Gonciarz, R. L.; Olshen, A. B.; Yeh, I.; Hann, B. C.; Zhao, N.; Wang, Y.-h.; Korkola, J.; Behr, S. C.; Evans, M. J.; collisson, e.; Renslo, A.
10.1101/2020.05.12.088971 — cancer biology — Posted on 2020-05-14
2885 A common human variant of GIPR improves systemic glucose homeostasis in a sexual dimorphic manner
Yammine, L.; Picatoste, B.; Abdullah, N.; Soares, D.; Leahey, R.; Gomez-Banoy, N.; Rosselot, C.; Wen, J.; Lo, J. C.; Garcia-Ocana, A.; McGraw, T. E.
10.1101/2020.05.12.091025 — physiology — Posted on 2020-05-14
2886 Catestatin (CST) is a key mediator of the immunoendocrine regulation of cardiovascular function
Ying, W.; Tang, K.; Avolio, E.; Schilling, J. M.; Pasqua, T.; Liu, M. A.; Mahata, S.; Bandyopadhyay, G. K.; Das, S.; Sahoo, D.; Webster, N. J.; Patel, H. H.; Ghosh, P.; Mahata, S. K.
10.1101/2020.05.12.092254 — physiology — Posted on 2020-05-14
2887 Testosterone enhances GLP-1 efficacy at the plasma membrane and endosomes to augment insulin secretion in male pancreatic β cells
Xu, W.; Ashford, F.; Bitsi, S.; Schiffer, L.; Qadir, F.; Arlt, W.; Tomas, A.; Hodson, D.; Mauvais-Jarvis, F.
10.1101/2020.05.12.081588 — physiology — Posted on 2020-05-14
2890 Phosphoproteomics identifies microglial Siglec-F inflammatory response during neurodegeneration
Morshed, N.; Ralvenius, W. T.; Nott, A.; Watson, L. A.; Rodriguez, F. H.; Akay, L. A.; Joughin, B. A.; Pao, P.-C.; Penney, J.; LaRocque, L.; Mastroeni, D.; Tsai, L.-H.; White, F. M.
10.1101/2020.05.12.090688 — neuroscience — Posted on 2020-05-14
2891 Combined pigment and metatranscriptomic analysis reveals synchronized diel patterns of phenotypic light response across domains in the open ocean
Becker, K. W.; Harke, M. J.; Mende, D. R.; Muratore, D.; Weitz, J. S.; DeLong, E. F.; Dyhrman, S. T.; Van Mooy, B. A. S.
10.1101/2020.05.12.091322 — molecular biology — Posted on 2020-05-14
2892 RTEL1 Influences the Abundance and Localization of TERRA RNA
Ghisays, F.; Garzia, A.; Wang, H.; Canasto-Chibuque, C.; Hohl, M.; Savage, S. A.; Tuschl, T.; Petrini, J. H. J.
10.1101/2020.05.12.088583 — molecular biology — Posted on 2020-05-14
2893 A putative long noncoding RNA-encoded micropeptide maintains cellular homeostasis in pancreatic β-cells
Li, M.; Shao, F.; Qian, Q.; Yu, W.; Zhang, Z.; Chen, B.; Dan, S.; Guo, Y.; Phan, A.-V. D.; Song, L.-S.; Stephens, S. B.; Sebag, J. A.; Imai, Y.; Ling, Y.; Cao, H.
10.1101/2020.05.12.091728 — molecular biology — Posted on 2020-05-14
2894 Integrated technology platform for accelerated discovery of antiviral antibody therapeutics
Gilchuk, P.; Bombardi, R. G.; Erasmus, J. H.; Tan, Q.; Nargi, R. S.; Soto, C.; Abbink, P.; Suscovich, T. J.; Dunellin, L. A.; Khandhar, A.; Archer, J.; Liang, J.; Fouch, M. E.; Davidson, E.; Doranz, B.; Jones, T.; Larson, E.; Ertel, S.; Granger, B.; Fuerte-Stone, J.; Roy, V.; Broge, T.; Linnekin, T. C.; Linde, C. H.; Gorman, M. J.; Nkolola, J.; Alter, G.; Reed, S. G.; Barouch, D. H.; Diamond, M. S.; Crowe, J. E.; Van Hoeven, N.; Thackray, L.; Carnahan, R. H.
10.1101/2020.05.12.090944 — immunology — Posted on 2020-05-14
2901 Complex small-world regulatory networks emerge from the 3D organisation of the human genome
Brackley, C. A.; Gilbert, N.; Michieletto, D.; Papantonis, A.; Pereira, M. C. F.; Cook, P. R.; Marenduzzo, D.
10.1101/2020.05.12.091041 — biophysics — Posted on 2020-05-14
2903 Circulating BMP9 protects the pulmonary endothelium during inflammation-induced lung injury in mice
Li, W.; Long, L.; Yang, X.; Tong, Z.; Southwood, M.; Caruso, P.; Upton, P. D.; Yang, P.; Bocobo, G.; Nikolic, I.; Higuera, A.; Salmon, R.; Jiang, H.; Lodge, K.; Hoenderdos, K.; Baron, R.; Yu, P. B.; Condliffe, A.; Summers, C.; Chilvers, E. R.; Morrell, N. W.
10.1101/2020.05.12.088880 — physiology — Posted on 2020-05-14
2906 FFA and OFA encode distinct types of face identity information
Tsantani, M.; Kriegeskorte, N.; Storrs, K.; Williams, A. L.; McGettigan, C.; Garrido, L.
10.1101/2020.05.12.090878 — neuroscience — Posted on 2020-05-14
2907 Electrophysiological correlates of visual backward masking in patients with bipolar disorder
Garobbio, S. A.; Roinishvili, M.; Favrod, O.; da Cruz, J. R.; Chkonia, E.; Brand, A.; Herzog, M. H.
10.1101/2020.05.12.090407 — neuroscience — Posted on 2020-05-14
2910 Coexistence of long and short DNA constructs within adhesion plaques
Li, L.; Kamal, M. A.; Stumpf, H.; Thibaudau, F.; Sengupta, K.; Smith, A.-S.
10.1101/2020.05.12.090357 — biophysics — Posted on 2020-05-14
2912 Determination and correction of aberrations in full field OCT using phase gradient autofocus by maximizing the likelihood function
Matkivsky, V.; Moiseev, A.; Shilyagin, P.; Rodionov, A.; Spahr, H.; Pfaffle, C.; Huttmann, G.; Hillmann, D.; Gelikonov, G.
10.1101/2020.05.12.089128 — biophysics — Posted on 2020-05-14
2914 Potent neutralization of SARS-CoV-2 in vitro and in an animal model by a human monoclonal antibody
Li, W.; Drelich, A.; Martinez, D. R.; Gralinski, L. E.; Chen, C.; Sun, Z.; Liu, X.; Zhelev, D. V.; Zhang, L.; Peterson, E. L.; Conard, A.; Mellors, J. W.; Tseng, C.-T.; Baric, R. S.; Dimitrov, D. S.
10.1101/2020.05.13.093088 — microbiology — Posted on 2020-05-14
2916 Growth factor receptor signaling inhibition prevents SARS-CoV-2 replication
Klann, K.; Bojkova, D.; Tascher, G.; Ciesek, S.; Muench, C.; Cinatl, J.
10.1101/2020.05.14.095661 — systems biology — Posted on 2020-05-14
2918 Novel ACE2-Independent Carbohydrate-Binding of SARS-CoV-2 Spike Protein to Host Lectins and Lung Microbiota
Chiodo, F.; Bruijns, S. C. M.; Rodriguez, E.; Li, R. J. E.; Molinaro, A.; Silipo, A.; Di Lorenzo, F.; Garcia-Rivera, D.; Valdes-Balbin, Y.; Verez-Bencomo, V.; van Kooyk, Y.
10.1101/2020.05.13.092478 — immunology — Posted on 2020-05-14
2919 PIDDosome-induced p53-activation for ploidy restriction facilitates hepatocarcinogenesis
Sladky, V. C.; Knapp, K.; Szabo, T. G.; Bongiovanni, L.; van den Bos, H.; Spierings, D. C. J.; Westendorp, B.; Stojakovic, T.; Scharnagl, H.; Timelthaler, G.; Tsuchia, K.; Pinter, M.; Foijer, F.; de Bruin, A.; Reiberger, T.; Rohr-Udilova, N.; Villunger, A.
10.1101/2020.05.13.092486 — cancer biology — Posted on 2020-05-14
2920 Hypoxia-Sensing CAR T-Cells Provide Safety and Efficacy in Treating Solid Tumors
Kosti, P.; Opzoomer, J.; Larios Martinez, K.; Henley-Smith, R.; Scudamore, C.; Okesola, M.; Taher, M.; Davies, D.; Muliaditan, T.; Larcombe-Young, D.; Woodman, N.; Gillett, C.; Thavaraj, S.; Maher, J.; Arnold, J.
10.1101/2020.05.13.091546 — synthetic biology — Posted on 2020-05-14
2923 Identification of Fusarium solani f. sp. pisi (Fsp) responsive genes in Pisum sativum
Willamson-Benavides, B. A.; Sharpe, R. M.; Nelson, G. M.; Bodah, E. T.; Porter, L. D.; Dhingra, A.
10.1101/2020.05.12.091892 — plant biology — Posted on 2020-05-14
2924 Identification of Avramr1 from Phytophthora infestans using long read and cDNA pathogen-enrichment sequencing (PenSeq)
Lin, X.; Song, T.; Fairhead, S.; Witek, K.; Jouet, A.; Jupe, F.; Witek, A. I.; Vleeshouwers, V. G. A. A.; Hein, I.; Jones, J. D. G.
10.1101/2020.05.14.095158 — genomics — Posted on 2020-05-14
2926 Scalable and flexible gene-environment interaction analysis in millions of samples
Westerman, K. E.; Pham, D. T.; Hong, L.; Chen, Y.; Sevilla-Gonzalez, M.; Sung, Y. J.; Sun, Y. V.; Morrison, A.; Chen, H.; Manning, A. K.
10.1101/2020.05.13.090803 — bioinformatics — Posted on 2020-05-14
2927 Chromosome-level genome assembly of the African pike, Hepsetus odoe
Du, X.; Hong, X.; Fan, G.; Huang, X.; Sun, S.; Ouyang, B.; Zhang, H.; Zhang, M.; Liu, S.; Liu, X.; Zhang, W.
10.1101/2020.05.13.094987 — genomics — Posted on 2020-05-14
2930 Control of RNA polymerase II promoter-proximal pausing by DNA supercoiling
Herrero-Ruiz, A.; Martinez-Garcia, P.; Terron-Bautista, J.; Lieberman, J. A.; Jimeno-Gonzalez, S.; Cortes-Ledesma, F.
10.1101/2020.05.12.091058 — molecular biology — Posted on 2020-05-14
2932 The eIF2α kinase HRI triggers the autophagic clearance of cytosolic protein aggregates
Abdel-Nour, M.; Ramaglia, V.; Bianchi, A. A.; Tsalikis, J.; Chau, H. N.; Kalia, S. K.; Kalia, L. V.; Chen, J.-J.; Arnoult, D.; Gommerman, J. L.; Philpott, D. J.; Girardin, S. E.
10.1101/2020.05.12.092072 — cell biology — Posted on 2020-05-14
2935 Regional, layer, and cell-class specific connectivity of the mouse default mode network
Whitesell, J. D.; Liska, A.; Coletta, L.; Hirokawa, K. E.; Bohn, P.; Williford, A.; Groblewski, P. A.; Graddis, N.; Kuan, L.; Knox, J. E.; Ho, A.; Wakeman, W.; Nicovich, P. R.; Nguyen, T. N.; Garren, E.; van Velthoven, C. T. J.; Fong, O.; Feng, D.; Naeemi, M.; Henry, A. M.; Dee, N.; Smith, K. A.; Levi, B. P.; Ng, L.; Tasic, B.; Zeng, H.; Mihalas, S.; Gozzi, A.; Harris, J. A.
10.1101/2020.05.13.094458 — neuroscience — Posted on 2020-05-14
2939 Medial Orbitofrontal Cortex Regulates Instrumental Conditioned Punishment, but not Pavlovian Conditioned Fear
Ma, C.; Jean-Richard-dit-Bressel, P.; Roughley, S.; Vissel, B.; Balleine, B.; Killcross, S.; Bradfield, L. A.
10.1101/2020.05.12.092205 — neuroscience — Posted on 2020-05-14
2940 Probing the functions of microglial cyclin-dependent kinase 5 under physiological and pathological conditions
Peng, Z.; Huang, W.-C.; Chen, M.; Penney, J.; Cam, H.; Abdurrob, F.; Akay, L.; Chen, X.; Ralvenius, W.; Rubino, L. P.; Tsai, L.-H.
10.1101/2020.05.12.090605 — neuroscience — Posted on 2020-05-14
2941 High concordance between hippocampal transcriptome of the intraamygdala kainic acid model and human temporal lobe epilepsy
Conte, G.; Parras, A.; Alves, M.; Olla, I.; de Diego-Garcia, L.; Beamer, E.; Alalqam, R.; Ocampo, A.; Mendez, R.; Lucas, J. J.; Engel, T.
10.1101/2020.05.12.092338 — neuroscience — Posted on 2020-05-14
2943 The impact of non-additive genetic associations on age-related complex diseases.
Guindo-Martinez, M.; Amela, R.; Bonas-Guarch, S.; Puiggros, M.; Salvoro, C.; Miguel-Escalada, I.; Carey, C. E.; Cole, J. B.; Rüeger, S.; Atkinson, E.; Leong, A.; Sanchez, F.; Ramon-Cortes, C.; Ejarque, J.; Palmer, D. S.; Kurki, M.; Aragam, K.; Florez, J. C.; Badia, R. M.; Mercader, J. M.; Torrents, D.
10.1101/2020.05.12.084608 — genomics — Posted on 2020-05-14
2945 Rewiring of peatland plant-microbe networks outpaces species turnover
Robroek, B. J.; Marti, M.; Svensson, B. H.; Dumont, M. G.; Veraart, A. J.; Jassey, V. E.
10.1101/2020.05.12.090274 — ecology — Posted on 2020-05-14
2946 A systematic dissection of human primary osteoblasts in vivo at single-cell resolution
gong, y.; Yang, J.; Li, X.; Zhou, C.; Chen, Y.; wang, z.; Qiu, X.; Liu, Y.; Zhang, H.; Greenbaum, J.; Chen, L.; Hu, Y.; Xie, J.; Yang, X.; Li, Y.; Bai, Y.; Wang, Y.-P.; Chen, Y.; Tan, L.-J.; Shen, H.; Xiao, H.; deng, H.-W.
10.1101/2020.05.12.091975 — bioinformatics — Posted on 2020-05-14
2950 Sphingolipids mediate polar sorting of PIN2 through phosphoinositide consumption at the trans-Golgi Network
Ito, Y.; Esnay, N.; Platre, M. P.; Noack, L. C.; Menzel, W.; Claverol, S.; Moreau, P.; Jaillais, Y.; Boutte, Y.
10.1101/2020.05.12.090399 — plant biology — Posted on 2020-05-14
2952 Dynamic dopaminergic activity controls the timing of self-timed movement
Hamilos, A. E.; Spedicato, G.; Hong, Y.; Sun, F.; Li, Y.; Assad, J. A.
10.1101/2020.05.13.094904 — neuroscience — Posted on 2020-05-14
2954 A cyclin-dependent kinase 5-derived peptide inhibits Cdk5/p25 activity and improves neurodegenerative phenotypes
Seo, J.; Pao, P.-C.; Kritskiy, O.; Lee, A.; Patnaik, D.; Watson, L. A.; Bula, M.; Barker, S. J.; Penney, J.; Silva, M. C.; Haggarty, S. J.; Tsai, L.-H.
10.1101/2020.05.12.090472 — neuroscience — Posted on 2020-05-14
2957 Haplotype-based heritability estimations reveal gestational duration as a maternal trait and fetal size measurements at birth as fetal traits in human pregnancy
Srivastava, A. K.; Juodakis, J.; Sole-Navais, P.; Chen, J.; Bacelis, J.; Teramo, K.; Hallman, M.; Njolstad, P. R.; Evans, D. M.; Jacobsson, B.; Muglia, L. J.; Zhang, G.
10.1101/2020.05.12.079863 — genetics — Posted on 2020-05-14
2959 Evolution of body size and wing shape trade-offs in arsenurine silkmoths
Hamilton, C. A.; Winiger, N.; Rubin, J. J.; Breinholt, J.; Rougerie, R.; Kitching, I. J.; Barber, J. R.; Kawahara, A. Y.
10.1101/2020.05.12.092197 — evolutionary biology — Posted on 2020-05-14
2961 Disease-relevant single cell photonic signatures identify S100β+ stem cells and their myogenic progeny in vascular lesions
Molony, C.; King, D.; di Luca, M.; Olayinka, A.; Hakimjavadi, R.; Julius, L. A.; Fitzpatrick, E.; Burtenshaw, D.; Healy, K.; Finlay, E.; Kernan, D.; Llobera, A.; Liu, W.; Morrow, D.; Redmond, E. M.; Ducree, J.; Cahill, P. A.
10.1101/2020.05.13.093518 — cell biology — Posted on 2020-05-14
2963 Promiscuous enzymes cooperate at the substrate level en route to lactazole A
Vinogradov, A. A.; Shimomura, M.; Kano, N.; Goto, Y.; Onaka, H.; Suga, H.
10.1101/2020.05.12.092031 — biochemistry — Posted on 2020-05-14
2965 Rational Design of Minimal Synthetic Promoters for Plants
Cai, Y.; Kallam, K.; Tidd, H.; Gendarini, G.; Salzman, A.; Patron, N. J.
10.1101/2020.05.14.095406 — synthetic biology — Posted on 2020-05-14
2966 Efficient Gene Targeting in Maize using Inducible CRISPR-Cas9 and Marker-Free Donor Template
Barone, P.; Wu, E.; Lenderts, B.; Anand, A.; Gordon-Kamm, W.; Svitashev, S.; Kumar, S.
10.1101/2020.05.13.093575 — plant biology — Posted on 2020-05-14
2969 Deep learning enables genetic analysis of the human thoracic aorta
Pirruccello, J.; Chaffin, M. D.; Fleming, S. J.; Arduini, A.; Lin, H.; Khurshid, S.; Chou, E. L.; Friedman, S. N.; Bick, A. G.; Weng, L.-C.; Choi, S. H.; Akkad, A.-D.; Batra, P.; Tucker, N. R.; Hall, A. W.; Roselli, C.; Benjamin, E. J.; Vellarikkal, S. K.; Gupta, R. M.; Stegman, C. M.; Ho, J. E.; Hoffmann, U.; Lubitz, S. A.; Philippakis, A.; Lindsay, M. E.; Ellinor, P. T.
10.1101/2020.05.12.091934 — genomics — Posted on 2020-05-14
2974 The role of conidia in the dispersal of Ascochyta rabiei
Khaliq, I.; Fanning, J.; Melloy, P.; Galloway, J.; Moore, K.; Burrell, D.; Sparks, A. H.
10.1101/2020.05.12.091827 — plant biology — Posted on 2020-05-14
2978 Identifying root traits affecting root-substrate adhesion in Arabidopsis using a novel centrifugation technique
Eldridge, B. M.; Larson, E. R.; Weldon, L.; Smyth, K. M.; Sellin, A. N.; Chenchiah, I. V.; Liverpool, T. B.; Grierson, C. S.
10.1101/2020.05.14.095448 — plant biology — Posted on 2020-05-14
2981 Effect of allelopathy on plant performance
Zhang, Z.; Liu, Y.; Yuan, L.; Weber, E.; van Kleunen, M.
10.1101/2020.05.14.095190 — ecology — Posted on 2020-05-14
2982 Sensitivity to food and cocaine cues are independent traits in a large sample of heterogeneous stock rats.
King, C. P.; Tripi, J. A.; Hughson, A. R.; Hovarth, A. P.; Lamparelii, A. C.; Holl, K. L.; Chitre, A. S.; Polesskaya, O.; Richards, J. B.; Solberg-Woods, L. C.; Palmer, A. A.; Robinson, T. E.; Flagel, S. B.; Meyer, P. J.
10.1101/2020.05.13.066944 — animal behavior and cognition — Posted on 2020-05-14
2984 Targeted mutation of barley (1,3;1,4)-β-glucan synthases reveals complex relationships between the storage and cell wall polysaccharide content
Garcia-Gimenez, G.; Barakate, A.; Smith, P.; Stephens, J.; Khor, S. F.; Doblin, M. S.; Hao, P.; Bacic, A.; Fincher, G. B.; Burton, R. A.; Waugh, R.; Tucker, M. R.; Houston, K.
10.1101/2020.05.13.093146 — plant biology — Posted on 2020-05-14
2986 Extended field-of-view ultrathin microendoscopes for high-resolution two-photon imaging with minimal invasiveness in awake mice
Antonini, A.; Sattin, A.; Moroni, M.; Bovetti, S.; Moretti, C.; Succol, F.; Forli, A.; Vecchia, D.; Rajamanickam, V. P.; Bertoncini, A.; Panzeri, S.; Liberale, C.; Fellin, T.
10.1101/2020.05.14.095299 — neuroscience — Posted on 2020-05-14
2990 Small interfering RNAs are highly effective inhibitors regarding Crimean-Congo hemorrhagic fever virus replication in vitro
Foldes, F.; Madai, M.; Papp, H.; Kemenesi, G.; Zana, B.; Geiger, L.; Gombos, K.; Somogyi, B.; Bock-Marquette, I.; Jakab, F.
10.1101/2020.05.13.093047 — microbiology — Posted on 2020-05-14
2991 In situ structure and organisation of the type IX secretion system
Gorasia, D. G.; Chreifi, G.; Seers, C. A.; Butler, C. A.; Heath, J. E.; Glew, M. D.; McBride, M. J.; Subramanian, P.; Kjaer, A.; Jensen, G. J.; Veith, P. D.; Reynolds, E. C.
10.1101/2020.05.13.094771 — microbiology — Posted on 2020-05-14
2992 Potential antiviral options against SARS-CoV-2 infection
Ianevski, A.; Yao, R.; Fenstad, M. H.; Biza, S.; Zusinaite, E.; Lysvand, H.; Loeseth, K.; Lamndsem, V. M.; Malmring, J. F.; Oksenych, V.; Erlandsen, S. E.; Aas, P. A.; Hagen, L.; Pettersen, C. H.; Afset, J. E.; Nordbo, S. A.; Bjoras, M.; Kainov, D. E.
10.1101/2020.05.12.091165 — microbiology — Posted on 2020-05-14
2994 Density modification of cryo-EM maps
Terwilliger, T. C.; Sobolev, O. V.; Afonine, P.; Adams, P. D. D.; Read, R. J.
10.1101/2020.05.13.091884 — biochemistry — Posted on 2020-05-14
2996 Development of a COVID-19 vaccine based on the receptor binding domain displayed on virus-like particles
Zha, L.; Zhao, H.; Mohsen, M. O.; Hong, L.; Zhou, Y.; Li, Z.; Yao, C.; Chen, H.; Liu, X.; Chang, X.; Zhang, J.; Li, D.; Wu, K.; Vogel, M.; Bachmann, M. F.; Wang, J.
10.1101/2020.05.06.079830 — immunology — Posted on 2020-05-14
2998 SARS-CoV-2 spike protein predicted to form stable complexes with host receptor protein orthologues from mammals
Lam, S. D.; Bordin, N.; Waman, V. P.; Scholes, H. M.; Ashford, P.; Sen, N.; van Dorp, L.; Rauer, C.; Dawson, N. L.; Pang, C. S.; Abbasian, M.; Sillitoe, I.; Edwards, S. J.; Fraternali, F.; Lees, J. G.; Santini, J. M.; Orengo, C. A.
10.1101/2020.05.01.072371 — bioinformatics — Posted on 2020-05-14
2999 Potential modes of COVID-19 transmission from human eye revealed by single-cell atlas
Hamashima, K.; Gautam, P.; Lau, K. A.; Khiong, C. W.; Blenkinsop, T. A.; Li, H.; Loh, Y. H.
10.1101/2020.05.09.085613 — genomics — Posted on 2020-05-14
3000 Whole genome sequencing and phylogenetic analysis of SARS-CoV-2 strains from the index and early patients with COVID-19 in Dubai, United Arab Emirates, 29 January to 18 March 2020
Abou Tayoun, A.; Loney, T.; Khansaheb, H.; Ramaswamy, S.; Harilal, D.; Deesi, Z.; Varghese, R.; Al Suwaidi, H.; Alkhajeh, A.; AlDabal, L.; Uddin, M.; Senok, A.; Hamoudi, R.; Halwani, R.; Hamid, Q.; Nowotny, N.; Alsheikh-Ali, A.
10.1101/2020.05.06.080606 — genomics — Posted on 2020-05-14
3002 Insulin receptor activation by proinsulin preserves synapses and vision in retinitis pigmentosa
Sanchez Cruz, A.; Hernandez Pinto, A.; Lillo, C.; Isiegas, C.; Marchena, M.; Lizasoain, I.; Bosch, F.; de la Villa, P.; Hernandez Sanchez, C.; de la Rosa, E. J.
10.1101/2020.05.13.092833 — neuroscience — Posted on 2020-05-14
3003 Live Imaging of Intracranial Lymphatics in the Zebrafish
Castranova, D.; Samasa, B.; Venero Galanternik, M.; Jung, H. M.; Pham, V. N.; Weinstein, B. M.
10.1101/2020.05.13.094581 — developmental biology — Posted on 2020-05-14
3004 Interactions of Upstream and Downstream Promoter Regions with RNA Polymerase are Energetically Coupled and a Target of Regulation in Transcription Initiation
Sosa, R. P.; Florez-Ariza, A. F.; Diaz Celis, C.; Onoa, B.; Cassago, A.; de Oliveira, P. S. L.; Portugal, R. V.; Guerra, D. G.; Bustamante, C. J.
10.1101/2020.05.13.070375 — biophysics — Posted on 2020-05-14
3008 Conserved anti-inflammatory effects and sensing of butyrate in zebrafish
Cholan, P. M.; Han, A.; Woodie, B. R.; Kurz, A. R.; Britton, W. J.; Ye, L.; Holmes, Z. C.; McCann, J. R.; David, L. A.; Rawls, J. F.; Oehlers, S. H.
10.1101/2020.05.13.069997 — immunology — Posted on 2020-05-14
3009 Repurposing low-molecular-weight drugs against the main protease of severe acute respiratory syndrome coronavirus 2
Gao, J.; Zhang, L.; Liu, X.; Li, F.; Ma, R.; Zhu, Z.; Zhang, J.; Wu, J.; Shi, Y.; Pan, Y.; Ge, Y.; Ruan, K.
10.1101/2020.05.05.079848 — biochemistry — Posted on 2020-05-14
3012 3D ultrastructural study of synapses in the human entorhinal cortex
Dominguez-Alvaro, M.; Montero-Crespo, M.; Blazquez-Llorca, L.; DeFelipe, J.; Alonso-Nanclares, L.
10.1101/2020.05.11.088435 — neuroscience — Posted on 2020-05-14
3014 Screening for New Interaction Partners for a Group IIB Intron Ribozyme with Surface Plasmon Resonance Imaging Coupled to MALDI Mass Spectrometry
Anders, U.; Gulotti-Georgieva, M.; Zelger-Paulus, S.; Hibti, F.-E.; Frydman, C.; Suckau, D.; Sigel, R. K. O.; Zenobi, R.
10.1101/2020.05.07.082776 — molecular biology — Posted on 2020-05-14
3016 Elements at the 5' end of Xist harbor SPEN-independent transcriptional antiterminator activity
Trotman, J. B.; Lee, D. M.; Cherney, R. E.; Kim, S. O.; Inoue, K.; Schertzer, M. D.; Bischoff, S. R.; Cowley, D. O.; Calabrese, M.
10.1101/2020.05.13.090506 — molecular biology — Posted on 2020-05-14
3018 TCF7L2 Silencing Reprograms the 4D Nucleome of Colorectal Cancer Cells
Brown, M. A.; Dotson, G. A.; Ronquist, S.; Emons, G.; Rajapakse, I.; Ried, T.
10.1101/2020.05.12.090845 — cancer biology — Posted on 2020-05-14
3019 SORBS2 is a genetic factor contributing to cardiac malformation of 4q deletion syndrome
Liang, F.; Zhang, X.; Wang, B.; Geng, J.; You, G.; Fa, J.; Sun, H.; Chen, H.; Fu, Q.; Zhang, Z.
10.1101/2020.05.12.087452 — genetics — Posted on 2020-05-14
3020 Oligomycins Inhibit Magnaporthe oryzae Triticum and suppress wheat blast disease
Chakraborty, M.; Mahmud, N. U.; Muzahid, A. N. M.; Rabby, S. M. F.; Islam, T.
10.1101/2020.05.13.094151 — microbiology — Posted on 2020-05-14
3021 A rapid, point of care red blood cell agglutination assay for detecting antibodies against SARS-CoV-2
Kruse, R. L.; Huang, Y.; Smetana, H.; Gehrie, E. A.; Amukele, T. K.; Tobian, A. A.; Mostafa, H. H.; Wang, Z. Z.
10.1101/2020.05.13.094490 — pathology — Posted on 2020-05-14
3024 A novel Ca2+ signalling pathway co-ordinates environmental phosphorus sensing and nitrogen metabolism in marine diatoms
Helliwell, K. E.; Harrison, E.; Christie-Oleza, J.; Rees, A.; Downe, J.; Aguilo-Ferretjans, M.; Al-Moosawi, L.; Brownlee, C.; Wheeler, G.
10.1101/2020.05.13.090282 — microbiology — Posted on 2020-05-14
3025 Tracing two causative SNPs reveals SARS-CoV-2 transmission in North America population
Ou, X.; Yang, Z.; Zhu, D.; Mao, S.; Wang, M.; Jia, R.; Chen, S.; Liu, M.; Yang, Q.; Wu, Y.; Zhao, X.; Zhang, S.; Huang, J.; Gao, Q.; Liu, Y.; Zhang, L.; Peopplenbosch, M.; Pan, Q.; Cheng, A.-c.
10.1101/2020.05.12.092056 — microbiology — Posted on 2020-05-14
3026 Phthiocerol dimycocerosates from Mycobacterium tuberculosis increase the membrane activity of bacterial effectors and host receptors
Augenstreich, J.; Haanappel, E.; Sayes, F.; Simeone, R.; Guillet, V.; Mazeres, S.; Chalut, C.; Mourey, L.; Brosch, R.; Guilhot, C.; Astarie-Dequeker, C.
10.1101/2020.05.13.092585 — microbiology — Posted on 2020-05-14
3027 Modelling the developmental spliceosomal craniofacial disorder Burn-McKeown syndrome using induced pluripotent stem cells
Wood, K. A.; Rowlands, C. F.; Thomas, H. B.; Woods, S.; OFlaherty, J.; Douzgou, S.; Kimber, S. J.; Newman, W. G.; O'Keefe, R.
10.1101/2020.05.13.094029 — genetics — Posted on 2020-05-14
3032 Insights into the genetic architecture of the human face
White, J. D.; Indencleef, K.; Naqvi, S.; Eller, R. J.; Roosenboom, J.; Lee, M. K.; Li, J.; Mohammed, J.; Richmond, S.; Quillen, E. E.; Norton, H. L.; Feingold, E.; Swigut, T.; Marazita, M. L.; Peeters, H.; Hens, G.; Shaffer, J. R.; Wysocka, J.; Walsh, S.; Weinberg, S. M.; Shriver, M. D.; Claes, P.
10.1101/2020.05.12.090555 — genetics — Posted on 2020-05-14
3033 NLRP3 controls ATM activation in response to DNA damage.
PETRILLI, V.; Bodnar-Wachtel, M.; Huber, A.-L.; Gorry, J.; Hacot, S.; Gerossier, L.; Guey, B.; Goutagny, N.; Bartosch, B.; Ballot, E.; Ghiringhelli, F.; Py, B.; Coute, Y.; Ballesta, A.; Lantuejoul, S.; Hall, J.
10.1101/2020.05.12.087015 — cancer biology — Posted on 2020-05-14
3034 PHERI - Phage Host Exploration tool.
Balaz, A.; Kajsik, M.; Budis, J.; Szemes, T.; Turna, J.
10.1101/2020.05.13.093773 — bioinformatics — Posted on 2020-05-14
3039 Aquaporins are main contributors of root hydraulic conductivity in pearl millet
Grondin, A.; Affortit, P.; Tranchant-Dubreuil, C.; de la Fuente Canto, C.; Mariac, C.; Gantet, P.; Vadez, V.; Vigouroux, Y.; Laplaze, L.
10.1101/2020.05.13.094094 — plant biology — Posted on 2020-05-14
3040 Rethinking GPS Navigation: Creating Cognitive Maps Through Auditory Clues
Clemenson, G. D.; Maselli, A.; Fiannaca, A.; Miller, A.; Gonzalez-Franco, M.
10.1101/2020.05.13.094219 — neuroscience — Posted on 2020-05-14
3043 In vivo analysis of Trypanosoma cruzi persistence foci at single cell resolution
Ward, A. I.; Lewis, M. D.; Khan, A.; McCann, C. J.; Francisco, A. F.; Jayawardhana, S.; Taylor, M. C.; Kelly, J. M.
10.1101/2020.05.13.092551 — microbiology — Posted on 2020-05-14
3044 Revisiting the gastrin-releasing peptide/bombesin system: A reverse-evolutionary study considering Xenopus
Hirooka, A.; Hamada, M.; Fujiyama, D.; Takanami, K.; Kobayashi, Y.; Oti, T.; Sakamoto, T.; Sakamoto, H.
10.1101/2020.05.13.093955 — evolutionary biology — Posted on 2020-05-13
3051 Structure of SARS-CoV-2 main protease in the apo state reveals the inactive conformation
Zhou, X.; Zhong, F.; Lin, C.; Hu, X.; Zhang, Y.; Xiong, B.; Yin, X.; Fu, J.; He, W.; Duan, J.; Fu, Y.; Zhou, H.; Wang, Q.; Li, J.; Zhang, J.
10.1101/2020.05.12.092171 — biochemistry — Posted on 2020-05-13
3053 Renal tubule Cpt1a overexpression mitigates kidney fibrosis by restoring mitochondrial homeostasis
Miguel, V.; Tituana, J.; Herrero, J. I.; Herrero, L.; Serra, D.; Cuevas, P.; Barbas, C.; Rodriguez-Puyol, D.; Marquez-Exposito, L.; Ruiz-Ortega, M.; Castillo, C.; Sheng, X.; Susztak, K.; Ruiz-Canela, M.; Salas-Salvado, J.; Hu, F. B.; Martinez Gonzalez, M. A.; Ortega, S.; Ramos, R.; Lamas, S.
10.1101/2020.02.18.952440 — biochemistry — Posted on 2020-05-13
3055 Auditory evoked potential (P300) in cochlear implant users: a scoping review.
Amaral, M. S. A. d.; Zamberlan-Amorin, N. E.; Mendes, K. D. S.; Bernal, S. C.; Massuda, E. T.; Hyppolito, M. A.; Reis, A. C. M. B.
10.1101/2020.05.13.094235 — neuroscience — Posted on 2020-05-13
3060 The cryo-electron microscopy structure of the human CDK-activating kinase
Greber, B. J.; Perez-Bertoldi, J. M.; Lim, K.; Iavarone, A. T.; Toso, D. B.; Nogales, E.
10.1101/2020.05.13.094755 — biochemistry — Posted on 2020-05-13
3061 Involvement of the Pseudomonas aeruginosa MexAB-OprM efflux pump in the secretion of the metallophore pseudopaline
Gomez, N. O.; Tetard, A.; Ouerdane, L.; Laffont, C.; Brutesco, C.; Ball, G.; Lobinski, R.; Denis, Y.; Plesiat, P.; Llanes, C.; Arnoux, P.; Voulhoux, R.
10.1101/2020.05.13.092411 — microbiology — Posted on 2020-05-13
3063 Comparison of the Accula SARS-CoV-2 Test with a Laboratory-Developed Assay for Detection of SARS-CoV-2 RNA in Clinical Nasopharyngeal Specimens
Hogan, C. A.; Garamani, N.; Lee, A. S.; Tung, J. K.; Sahoo, M. K.; Huang, C.; Stevens, B.; Zehnder, J.; Pinsky, B. A.
10.1101/2020.05.12.092379 — microbiology — Posted on 2020-05-13
3064 Conserved anti-inflammatory effects and sensing of butyrate in zebrafish
Cholan, P. M.; Han, A.; Woodie, B. R.; Kurz, A. R.; Britton, W. J.; Ye, L.; Holmes, Z. C.; McCann, J. R.; David, L. A.; Rawls, J. F.; Oehlers, S. H.
10.1101/2020.05.13.069997 — immunology — Posted on 2020-05-13
3065 Strain-dependent modifier genes determine survival in Zfp423 mice
Alcaraz, W. A.; Liu, Z.; Valdes, P.; Chen, E.; Valdovino Gonzalez, A. G.; Wade, S.; Wong, C.; Kim, E.; Chen, H.-H. M.; Concepcion, D.; Hamilton, B. A.
10.1101/2020.05.12.091629 — genetics — Posted on 2020-05-13
3067 Recellularization of bronchial extracellular matrix with primary bronchial smooth muscle cells
Ben Hamouda, S.; Vargas, A.; Boivin, R.; Miglino, M. A.; da Palma, R. K.; Lavoie, J.-P.
10.1101/2019.12.23.878645 — cell biology — Posted on 2020-05-13
3071 Human dental pulp stem cells: a sanctuary for relapsing Bartonella quintana.
Oumarou Hama, H.; Hamada, A.; Aboudharam, G.; Ghigo, E.; Drancourt, M.
10.1101/2020.05.13.094037 — microbiology — Posted on 2020-05-13
3072 IRRIGATION LEVELS AND SOIL COVERS IN CARROT CROP
Vieira, J. H.; Aleman, C. C.; de Freitas, E. M.; Santos, L. d. A.; Da Silva, G. H.; Fernandes, P. H. F.
10.1101/2020.05.13.094128 — ecology — Posted on 2020-05-13
3077 ChAdOx1 nCoV-19 vaccination prevents SARS-CoV-2 pneumonia in rhesus macaques
van Doremalen, N.; Lambe, T.; Spencer, A.; Belij-Rammerstorfer, S.; Purushotham, J.; Port, J.; Avanzato, V.; Bushmaker, T.; Flaxman, A.; Ulaszewska, M.; Feldmann, F.; Allen, E.; Sharpe, H.; Schulz, J.; Holbrook, M.; Okumura, A.; Meade-White, K.; Perez-Perez, L.; Bissett, C.; Gilbride, C.; Williamson, B.; Rosenke, R.; Long, D.; Ishwarbhai, A.; Kailath, R.; Rose, L.; Morris, S.; Powers, C.; Lovaglio, J.; Hanley, P.; Scott, D.; Saturday, G.; de Wit, E.; Gilbert, S. C.; Munster, V.
10.1101/2020.05.13.093195 — microbiology — Posted on 2020-05-13
3078 Quantifying variation in bacterial reproductive fitness with and without antimicrobial resistance: a high-throughput method
Frey, P. M.; Baer, J.; Bergada Pijuan, J.; Lawless, C.; Bühler, P. K.; Kouyos, R. D.; Lemon, K. P.; Zinkernagel, A. S.; Brugger, S. D.
10.1101/2020.05.13.093807 — microbiology — Posted on 2020-05-13
3087 DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junction
Li, G.; Pan, P.; Shen, M.; Yu, Z.; Ge, W.; Lao, Z.; Fan, Y.; Chen, K.; Ding, Z.; Wang, W.; Wan, P.; Shereen, M. A.; Luo, Z.; Chen, X.; Zhang, Q.; Lin, L.; Wu, J.
10.1101/2020.05.13.094136 — microbiology — Posted on 2020-05-13
3090 Antibody repertoire induced by SARS-CoV-2 spike protein immunogens
Ravichandran, S.; Coyle, E. M.; Klenow, L.; Tang, J.; Grubbs, G.; Liu, S.; Wang, T.; Golding, H.; Khurana, S.
10.1101/2020.05.12.091918 — microbiology — Posted on 2020-05-13
3091 Mediocremonas mediterraneus, a New Member within the Developea
Weiler, B. A.; Sa, E.; Sieracki, M. E.; Massana, R.; del Campo, J.
10.1101/2020.05.12.090621 — microbiology — Posted on 2020-05-13
3092 Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein
Zost, S. J.; Gilchuk, P.; Chen, R.; Case, J. B.; Reidy, J. X.; Trivette, A.; Nargi, R. S.; Sutton, R. E.; Suryadevara, N.; Chen, E. C.; Binshtein, E.; Shrihari, S.; Ostrowski, M. A.; Chu, H. Y.; Didier, J. E.; MacRenaris, K. W.; Jones, T.; Day, S.; Myers, L.; Lee, F. E.-H.; Nguyen, D. C.; Sanz, I.; Martinez, D. R.; Gralinski, L.; Baric, R. S.; Thackray, L.; Diamond, M. S.; Carnahan, R. H.; Crowe, J. E.
10.1101/2020.05.12.091462 — immunology — Posted on 2020-05-13
3098 A CRISPR/Cas9-Based Approach For Editing Immortalised Human Myoblasts To Model Duchenne Muscular Dystrophy In Vitro
Soblechero-Martin, P.; Albiasu-Arteta, E.; Anton-Martinez, A.; Garcia-Jimenez, I.; Gonzalez-Iglesias, G.; Larranaga-Aiestaran, I.; Lopez-Martinez, A.; Poyatos-Garcia, J.; Ruiz-Del-Yerro, E.; Gonzalez, F.; Arechavala-Gomeza, V.
10.1101/2020.02.24.962316 — neuroscience — Posted on 2020-05-13
3099 Evaluation Of SYBR Green Real Time PCR For Detecting SARS-CoV-2 From Clinical Samples
Fajardo, A.; Pereira-Gomez, M.; Echeverria, N.; Lopez-Tort, F.; Perbolianachis, P.; Aldunate, F.; Moreno, P.; Moratorio, G.
10.1101/2020.05.13.093609 — molecular biology — Posted on 2020-05-13
3101 Comparison of SARS-CoV-2 Indirect and Direct Detection Methods
Bremner, R.; Pearson, J. D.; Trcka, D.; Hyduk, S. J.; Aynaud, M.-M.; Hernandez, J. J.; Peidis, F.; Lu, S.; Chan, K.; Woodgett, J.; Mazzulli, T.; Attisano, L.; Pelletier, L.; Cybulsky, M. I.; Wrana, J. L.
10.1101/2020.05.12.092387 — microbiology — Posted on 2020-05-13
3103 In Vitro Inhibition of SARS-CoV-2 Infection by Bovine Lactoferrin
Carvalho, C. A. M.; Matos, A. R.; Caetano, B. C.; Sousa Junior, I. P.; Campos, S. P. C.; Geraldino, B. R.; Barros, C. A.; Almeida, M. A. P.; Rocha, V. P.; Silva, A. M. V.; Melgaco, J. G.; Neves, P. C. C.; Azamor, T.; Ano Bom, A. P. D.; Siqueira, M. M.; Missailidis, S.; Goncalves, R. B.
10.1101/2020.05.13.093781 — microbiology — Posted on 2020-05-13
3107 A new paradigm for Prelamin A proteolytic processing by ZMPSTE24: the upstream SY^LL cleavage occurs first and there is no CaaX processing by ZMPSTE24
Nie, L.; Spear, E.; Babatz, T. D.; Quigley, A.; Dong, Y. Y.; Chu, A.; Rotty, B.; Chalk, R.; Mukhopadhyay, S. M. M.; Burgess-Brown, N. A.; Pike, A. C. W.; Young, S. G.; Michaelis, S.; Carpenter, E. P.
10.1101/2020.05.13.093849 — biochemistry — Posted on 2020-05-13
3108 An original structural fold underlies the multitask P1, a silencing suppressor encoded by the Rice yellow mottle virus
Poignavent, V.; Hoh, F.; Terral, G.; Yang, Y.; Gillet, F.-x.; Kim, J. H.; Allemand, F.; Lacombe, E.; Brugidou, C.; Cianferani, S.; Demene, H.; Vignols, F.
10.1101/2020.02.24.963488 — pathology — Posted on 2020-05-13
3110 Functional MRI of large scale activity in behaving mice
Fonseca, M. S.; Bergomi, M. G.; Mainen, Z. F.; Shemesh, N.
10.1101/2020.04.16.044941 — neuroscience — Posted on 2020-05-13
3111 A point mutation in Ttc26 causes lumbar spinal cord fusion and synchronous hind-limb locomotion in hop mice
Bernhardt, N.; Memic, F.; Velica, A.; Tran, M. A.; Vieillard, J.; Chersa, T.; Andersson, L.; Whelan, P. J.; Boije, H.; Kullander, K.
10.1101/2020.05.13.093799 — neuroscience — Posted on 2020-05-13
3114 Visualizing the dynamics of exported bacterial proteins with the chemogenetic fluorescent reporter FAST
Chekli, Y.; Peron-Cane, C.; Dell'Arciprete, D.; Allemand, J.-F.; Li, C.; GHIGO, J.-M.; Gautier, A.; Lebreton, A.; Desprat, N.; BELOIN, C.
10.1101/2020.05.12.090142 — microbiology — Posted on 2020-05-13
3115 Characterization of miRNAs encoded by Autographa californica nucleopolyhedrovirus
Wang, J.; Xing, K.; Xiong, P.; Liang, H.; Zhu, M.; Huang, S.; Zhao, J.; Yu, X.; Ning, X.; Li, R.; Wang, X.
10.1101/2020.05.13.094193 — microbiology — Posted on 2020-05-13
3116 Pleiotropy-guided transcriptome imputation from normal and tumor tissues identifies new candidate susceptibility genes for breast and ovarian cancer
Kar, S.; Considine, D.; Tyrer, J.; Plummer, J.; Chen, S.; Dezem, F.; Barbeira, A.; Rajagopal, P.; Rosenow, W.; Anton, F.; Bodelon, C.; Chang-Claude, J.; Chenevix-Trench, G.; deFazio, A.; Doerk, T.; Ekici, A.; Ewing, A.; Fountzilas, G.; Goode, E.; Hartman, M.; Heitz, F.; Hillemanns, P.; Hogdall, E.; Hogdall, C.; Huzarski, T.; Jensen, A.; Karlan, B.; Khusnutdinova, E.; Kiemeney, L.; Kjaer, S.; Klapdor, R.; Kobel, M.; Li, J.; Liebrich, C.; May, T.; Olsson, H.; Permuth, J.; Peterlongo, P.; Radice, P.; Ramus, S.; Riggan, M.; Risch, H.; Saloustros, E.; Simard, J.; Szafron, L.; Thompson, C.; Vierkant
10.1101/2020.04.23.043653 — genetics — Posted on 2020-05-13
3118 LDpred-funct: incorporating functional priors improves polygenic prediction accuracy in UK Biobank and 23andMe data sets
Marquez-Luna, C.; Gazal, S.; Loh, P.-R.; Kim, S. S.; Furlotte, N.; Auton, A.; 23andMe Research Team, ; Price, A. L.
10.1101/375337 — genetics — Posted on 2020-05-13
3120 Recombinant BCG overexpressing a STING agonist elicits trained immunity and improved antitumor efficacy in non-muscle invasive bladder
Singh, A. K.; Praharaj, M.; Lombardo, K. A.; Yoshida, T.; Matoso, A.; Baras, A. S.; Zhao, L.; Prasad, P.; Powell, J. D.; Kates, M.; McConkey, D.; Pardoll, D. M.; Bishai, W. R.; Bivalacqua, T. J.
10.1101/2020.04.25.061531 — cancer biology — Posted on 2020-05-13
3121 Crystal Structure of the Werner's Syndrome Helicase
Newman, J. A.; Gavard, A. E.; Lieb, S.; Ravichandran, M. C.; Hauer, K.; Werni, P.; Geist, L.; Boettcher, J.; Engen, J. R.; Rumpel, K.; Samwer, M.; Petronczki, M.; Gileadi, O.
10.1101/2020.05.04.075176 — biochemistry — Posted on 2020-05-13
3122 Impact of industrial production system parameters on chicken microbiomes: mechanisms to improve performance and reduce Campylobacter
McKenna, A.; Ijaz, U. Z.; Kelly, C.; Linton, M.; Sloan, W. T.; Green, B. D.; Lavery, U.; Dorrell, N.; Wren, B. W.; Richmond, A.; Corcionivoschi, N.; Gundogdu, O.
10.1101/2020.05.10.084251 — microbiology — Posted on 2020-05-13
3130 Auranofin inhibits virulence in Pseudomonas aeruginosa
Tan, L. Z. W.; Yam, J. K. H.; Hong, Z.; Salido, M. M. S.; Woo, B. Y.; Li, S. F. Y.; Yang, L.; Givskov, M.; Chng, S.-S.
10.1101/198820 — microbiology — Posted on 2020-05-13
3131 Gfral-expressing Neurons Suppress Food Intake via Aversive Pathways
Sabatini, P. V.; Henriette Frikke-Schmidt, H.; Arthurs, J.; Gordian, D.; Patel, A.; Adams, J. M.; Wang, J.; Beck Jorgensen, S.; Olson, D. P.; Palmiter, R. D.; Myers, M. G.; Seeley, R. J.
10.1101/2020.05.11.088773 — neuroscience — Posted on 2020-05-13
3133 Viscoelastic mapping of mouse brain tissue: relation to structure and age
Antonovaite, N.; Hulshof, L. A.; Hol, E. M.; Wadman, W. J.; Iannuzzi, D.
10.1101/2020.05.11.089144 — neuroscience — Posted on 2020-05-13
3135 Listeria monocytogenes personalized cancer vaccines drive therapeutic immune responses to cancer derived neoantigens
Coder, B.; Pryshchep, O.; Kelkar, D.; Filippova, E.; Ju, X.; Balli, D.; Mottershead, C.; Ramos, K.; Thambi, N.; Cheng, Z.; Vander Lugt, B.; Lesch, J.; Liu, X.; DeVoss, J.; Cooke, K.; Liu, S.; Zhan, J.; Mitchell, P.; Villarreal, D. O.; Hayes, S. M.; Johnston, J. A.; Petit, R.; Phee, H.; Princiotta, M.
10.1101/2020.05.11.088930 — immunology — Posted on 2020-05-13
3136 The kinetic landscape of an RNA binding protein in cells
Sharma, D.; Zagore, L. L.; Brister, M. M.; Ye, X.; Crespo-Hernández, C. E.; Licatalosi, D.; Jankowsky, E.
10.1101/2020.05.11.089102 — biochemistry — Posted on 2020-05-13
3138 CTLA-4 blockade reverses the Foxp3+ T-regulatory-cell suppression of anti-tuberculosis T-cell effector responses
Shao, L.; Gao, Y.; Shao, X.; Ou, Q.-f.; Zhang, S.; Liu, Q.; Zhang, B.; Wu, J.; Ruan, Q.; Shen, L.; Weng, X.; Zhang, W.; Chen, Z. W.
10.1101/2020.05.11.089946 — immunology — Posted on 2020-05-13
3142 EpiDope: A Deep neural network for linear B-cell epitope prediction
Collatz, M.; Mock, F.; Hoelzer, M.; Barth, E.; Sachse, K.; Marz, M.
10.1101/2020.05.12.090019 — bioinformatics — Posted on 2020-05-13
3144 Phage-DMS: a comprehensive method for fine mapping of antibody epitopes
Garrett, M. E.; Itell, H. L.; Crawford, K. H. D.; Basom, R.; Bloom, J. D.; Overbaugh, J.
10.1101/2020.05.11.089342 — immunology — Posted on 2020-05-13
3147 The Dynamics of Plant Nutation
Raja, V.; Silva, P. L.; Holghoomi, R.; Calvo, P.
10.1101/2020.05.11.089466 — plant biology — Posted on 2020-05-13
3149 Nuclear IQGAP1 promotes gastric cancer cell growth by altering the splicing of a cell-cycle regulon in co-operation with hnRNPM
Birladeanu, A.; Rogalska, M.; Potiri, M.; Papadaki, V.; Andreadou, M.; Kontoyiannis, D. L.; Erpapazoglou, Z.; Lewis, J. D.; Kafasla, P.
10.1101/2020.05.11.089656 — molecular biology — Posted on 2020-05-13
3150 FSC-Q: A CryoEM map-to-atomic model quality validation based on the local Fourier Shell Correlation
Ramirez-Aportela, E.; Maluenda, D.; Fonseca, Y. C.; Conesa, P.; Marabini, R.; Heymann, J. B.; Carazo, J. M.; Sorzano, C. O. S.
10.1101/2020.05.12.069831 — biophysics — Posted on 2020-05-13
3152 Leukemia cell of origin influences apoptotic priming and sensitivity to LSD1 inhibition
Cai, S. F.; Chu, S. H.; Goldberg, A. D.; Parvin, S.; Koche, R. P.; Glass, J. L.; Stein, E. M.; Tallman, M. S.; Sen, F.; Famulare, C.; Cusan, M.; Huang, C.-H.; Chen, C.-W.; Zou, L.; Cordner, K. B.; DelGaudio, N. L.; Durani, V.; Kini, M.; Rex, M.; Tian, H. S.; Zuber, J. L.; Baslan, T.; Lowe, S. W.; Rienhoff, H. Y.; Letai, A.; Levine, R. L.; Armstrong, S. A.
10.1101/2020.05.11.089060 — cancer biology — Posted on 2020-05-13
3156 SIRPalpha on mouse B1 cells restricts lymphoid tissue migration and natural antibody production
van den Berg, T.; Franke, K.; Pillai, S. Y.; Hoogenboezem, M.; Gijbels, M. J. J.; Matlung, H. L.; Geissler, J.; Olsman, H.; Pottgens, C.; van Gorp, P. J.; Ozsvar-Kozma, M.; Saito, Y.; Matozaki, T.; Kuijpers, T. W.; Hendriks, R. W.; Kraal, G.; Binder, C. J.; de Winther, M. P. J.
10.1101/2020.05.13.092494 — immunology — Posted on 2020-05-13
3157 FLEXIQuant-LF: Robust Regression to Quantify Protein Modification Extent in Label-Free Proteomics Data
Kahnert, K.; Schlaffner, C. N.; Muntel, J.; Chauhan, R.; Renard, B. Y.; Steen, J. A.; Steen, H.
10.1101/2020.05.11.088492 — bioinformatics — Posted on 2020-05-13
3159 Transcriptional regulation of genes involved in Zn transport after foliar Zn application to Medicago sativa
Cardini, A.; Elisa Pellegrino, E.; White, P. J.; Mazzolai, B.; Mascherpa, M. C.; Ercoli, L.
10.1101/2020.05.11.088617 — plant biology — Posted on 2020-05-13
3162 Targeting the latent human cytomegalovirus reservoir with virus specific nanobodies
De Groof, T. W. M.; Elder, E. G.; Heukers, R.; Lim, E. Y.; Wills, M.; Sinclair, J. H.; Smit, M. J.
10.1101/2020.05.12.071860 — microbiology — Posted on 2020-05-13
3164 Immune landscape of a genetically-engineered murine model of glioma relative to human glioma by single-cell sequencing
Zamler, D. B.; Shingu, T.; Kahn, L. M.; Kassab, C.; Ott, M.; Tomczak, K.; Liu, J.; Li, Y.; Lai, I. P.; Yee, C.; Rai, K.; Heimberger, A. B.; Draetta, G.; Hu, J.
10.1101/2020.05.11.088708 — cancer biology — Posted on 2020-05-13
3165 Ion Identity Molecular Networking in the GNPS Environment
Schmid, R.; Petras, D.; Nothias, L.-F.; Wang, M.; Aron, A. T.; Jagels, A.; Tsugawa, H.; Rainer, J.; Garcia-Aloy, M.; Duehrkop, K.; Korf, A.; Pluskal, T.; Kamenik, Z.; Jarmusch, A. K.; Caraballo-Rodriguez, A. M.; Weldon, K.; Nothias-Esposito, M.; Aksenov, A. A.; Bauermeister, A.; Albarracin-Orio, A.; Grundmann, C. O.; Vargas, F.; Koester, I.; Gauglitz, J. M.; Gentry, E. C.; Hoevelmann, Y.; Kalinina, S. A.; Pendergraft, M. A.; Panitchpakdi, M. W.; Tehan, R.; Le Gouellec, A.; Aleti, G.; Mannochio Russo, H.; Arndt, B.; Huebner, F.; Hayen, H.; Zhi, H.; Raffatellu, M.; Prather, K. A.; Aluwihare, L.
10.1101/2020.05.11.088948 — bioinformatics — Posted on 2020-05-13
3167 Human follicular CD4 T cell function is defined by specific molecular, positional and TCR dynamic signatures.
Padhan, K.; Moysi, E.; Noto, A.; Chassiakos, A.; Ghneim, K.; Shah, S.; Papaioannou, V.; Fabozzi, G.; Ambrozak, D.; Poultsidi, A.; Ioannou, M.; Fenwik, C.; Darko, S.; Douek, D. C.; Sekaly, R.-P.; Pantaleo, G.; Koup, R. A.; Petrovas, C.
10.1101/2020.05.12.089706 — immunology — Posted on 2020-05-13
3171 Plasmacytoid dendritic cell expansion defines a distinct subset of RUNX1 mutated acute myeloid leukemia
Xiao, W.; Chan, A.; Waarts, M. R.; Mishra, T.; Liu, Y.; Cai, S. F.; Yao, J.; Gao, Q.; Bowman, R. L.; Koche, R.; Csete, I. S.; Baik, J.; Yanis, S.; Famulare, C.; Patel, M.; Arcila, M. E.; Stahl, M.; Rampal, R. K.; Tallman, M. S.; Zhang, Y.; Dogan, A.; Goldberg, A. D.; Roshal, M.; Levine, R.
10.1101/2020.05.11.088872 — pathology — Posted on 2020-05-13
3173 REV-ERBalpha mediates complement expression and circadian regulation of microglial synaptic phagocytosis
Griffin, P.; Sheehan, P. W.; Dimitry, J. M.; Guo, C.; Kanan, M. F.; Lee, J.; Zhang, J.; Musiek, E. S.
10.1101/2020.05.11.088443 — neuroscience — Posted on 2020-05-13
3177 Non-canonical role for Lpar1-EGFP subplate neurons in early postnatal somatosensory cortex
Ghezzi, F.; Marques-Smith, A.; Anastasiades, P. G.; Lyngholm, D.; Vagnoni, C.; Rowett, A.; Hoerder-Suabedissen, A.; Nakagawa, Y.; Molnar, Z.; Butt, S. J. B.
10.1101/2020.05.12.088450 — neuroscience — Posted on 2020-05-13
3178 Single-soma transcriptomics of tangle-bearing neurons in Alzheimer's disease reveals the signatures of tau-associated synaptic dysfunction
Otero-Garcia, M.; Xue, Y.-Q.; Shakouri, T.; Deng, Y.; Morabito, S.; Allison, T.; Lowry, W. E.; Kawaguchi, R.; Swarup, V.; Cobos, I.
10.1101/2020.05.11.088591 — neuroscience — Posted on 2020-05-13
3180 Genome-scale phylogeny and contrasting modes of genome evolution in the fungal phylum Ascomycota
Shen, X.-X.; Steenwyk, J. L.; LaBella, A. L.; Opulente, D. A.; Zhou, X.; Kominek, J.; Li, Y.; Groenewald, M.; Hittinger, C. T.; Rokas, A.
10.1101/2020.05.11.088658 — evolutionary biology — Posted on 2020-05-13
3181 iDePP: a genetically encoded system for the inducible depletion of PI(4,5)P2 in Arabidopsis thaliana.
Doumane, M.; Colin, L.; Lebecq, A.; Fangain, A.; Bareille, J.; Hamant, O.; Belkhadir, Y.; Jaillais, Y.; Caillaud, M.-C.
10.1101/2020.05.13.091470 — plant biology — Posted on 2020-05-13
3182 CryoEM Structure of CtBP2 Confirms Tetrameric Architecture
Jecrois, A. M.; Dcona, M. M.; Deng, X.; Bandyopadhyay, D.; Grossman, S. R.; Schiffer, C. A.; Royer, W. E.
10.1101/2020.04.06.027573 — biochemistry — Posted on 2020-05-13
3185 Visual stimulus-specific habituation of innate defensive behaviour in mice
Tafreshiha, A.; Van den Burg, S. A.; Smits, K.; Blömer, L. A.; Heimel, J. A.
10.1101/2020.05.11.087825 — neuroscience — Posted on 2020-05-13
3186 3D ultrastructural study of synapses in the human entorhinal cortex
Dominguez-Alvaro, M.; Montero-Crespo, M.; Blazquez-Llorca, L.; DeFelipe, J.; Alonso-Nanclares, L.
10.1101/2020.05.11.088435 — neuroscience — Posted on 2020-05-13
3190 Evaluation of the EUROIMMUN Anti-SARS-CoV-2 ELISA Assay for detection of IgA and IgG antibodies
Matushek, S.; Beavis, K. G.; Abeleda, A.; Bethel, C.; Hunt, C.; Gillen, S.; Moran, A.; Tesic, V.
10.1101/2020.05.11.089862 — microbiology — Posted on 2020-05-13
3191 Dopaminergic neurons establish a distinctive axonal arbor with a majority of non-synaptic terminals
Ducrot, C.; Bourque, M.-J.; Delmas, C. V. L.; Racine, A.-S.; Bello, D. G.; Delignat-Lavaud, B.; Lycas, M. D.; Fallon, A.; Michaud-Tardif, C.; Burke Nanni, S.; Herborg, F.; Gether, U.; Nanci, A.; Takahashi, H.; Parent, M.; Trudeau, L.-E.
10.1101/2020.05.11.088351 — neuroscience — Posted on 2020-05-13
3193 High dimensional single-cell analysis reveals iNKT cell developmental trajectories and effector fate decision
Baranek, T.; Lebrigand, K.; de Amat Herbozo, C.; Gonzalez, L.; Bogard, G.; Dietrich, C.; Magnone, V.; Boisseau, C.; Jouan, Y.; Trottein, F.; Si-Tahar, M.; Leite-de-Moraes, M.; Mallevaey, T.; Paget, C.
10.1101/2020.05.12.070425 — immunology — Posted on 2020-05-13
3194 Reduced purine biosynthesis in humans after their divergence from Neandertals
Stepanova, V.; Moczulska, K. E.; Vacano, G. N.; Ju, X.-c.; Riesenberg, S.; Macak, D.; Maricic, T.; Dombrowski, L.; Schörnig, M.; Anastassiadis, K.; Baker, O.; Naumann, R.; Khrameeva, E. E.; Vanyushkina, A.; Stekolschikova, E.; Kurochkin, I.; Mazzarino, R.; Duval, N.; Zubkov, D.; Giavalisco, P.; Wilkinson, T. G.; Patterson, D.; Khaitovich, P.; Pääbo, S.
10.1101/2020.05.11.087338 — evolutionary biology — Posted on 2020-05-13
3196 Titan Mice are Unique Short-Lived Mammalian Model of Metabolic Syndrome and Aging
Peleg, S.; German Mouse Clnic (GMC), ; de-Diego, I.; Sanz-Moreno, A.; Müller-Eigner, A.; Venkateswaran Venkatasubramani, A.; Langhammer, M.; Gerlini, R.; Rathkolb, B.; Aguilar-Pimentel, A.; Klein-Rodewald, T.; Calzada-Wack, J.; Becker, L.; Imhof, A.; Meng, C.; Ludwig, C.; Koch, F.; von Krusenstiern, E.; Varner, E. L.; Snyder, N. W.; Caton, V.; Brenmoehl, J.; Hoeflich, A.; Fuchs, H.; Gailus-Durner, V.; Hrabe de Angelis, M.
10.1101/2020.05.11.088625 — biochemistry — Posted on 2020-05-13
3197 Phe-Gly Motifs Drive Fibrillization of TDP-43's Prion-Like Domain Droplets
Pantoja-Uceda, D.; Stuani, C.; Laurents, D. V.; McDermott, A. E.; Buratti, E.; Mompean, M.
10.1101/2020.02.20.957969 — biophysics — Posted on 2020-05-13
3198 An original structural fold underlies the multitask P1, a silencing suppressor encoded by the Rice yellow mottle virus
Poignavent, V.; Hoh, F.; Terral, G.; Yang, Y.; Gillet, F.-x.; Kim, J. H.; Allemand, F.; Lacombe, E.; Brugidou, C.; Cianferani, S.; Demene, H.; Vignols, F.
10.1101/2020.02.24.963488 — pathology — Posted on 2020-05-13
3199 Microrheology reveals microscale viscosity gradients in planktonic systems
Guadayol, O.; Mendonca, T.; Segura-Noguera, M.; Wright, A. J.; Tassieri, M.; Humphries, S.
10.1101/2020.04.09.033464 — ecology — Posted on 2020-05-13
3200 Platelet Derived Growth Factor Receptor β (PDGFRβ) is a Host Receptor for the human malaria parasite adhesin TRAP
Steel, R. W. J.; Vigdorovich, V.; Dambrauskas, N.; Wilder, B. K.; Arredondo, S. A.; Goswami, D.; Kumar, S.; Carbonetti, S.; Swearingen, K. E.; Nguyen, T.; Betz, W.; Camargo, N.; Fisher, B. S.; Soden, J.; Thomas, H.; Freeth, J.; Moritz, R. L.; Sather, D. N.; Kappe, S. H. I.
10.1101/2020.05.12.091488 — microbiology — Posted on 2020-05-13
3201 Inhibition of TRPV1 and TRPA1 by mosquito and mouse saliva
Li, T.; Derouiche, S.; Sakai, Y.; Uta, D.; Aoyagi, S.; Tominaga, M.
10.1101/2020.05.12.090985 — cell biology — Posted on 2020-05-13
3202 Structures of the stator complex that drives rotation of the bacterial flagellum
Deme, J.; Johnson, S.; Vickery, O.; Muellbauer, A.; Monkhouse, H.; Griffiths, T.; Hennell-James, R.; Berks, B.; Coulton, J.; Stansfeld, P. J.; Lea, S. M.
10.1101/2020.05.12.089201 — biochemistry — Posted on 2020-05-13
3205 Hematopoietic progenitors polarize in contact with bone marrow stromal cells by engaging CXCR4 receptors.
Bessy, T.; Souquet, B.; Vianay, B.; Schaeffer, A.; Jaffredo, T.; Larghero, J.; Blanchoin, L.; Brunet, S.; Faivre, L.; Thery, M.
10.1101/2020.05.11.089292 — cell biology — Posted on 2020-05-13
3206 Skeletal muscle-derived Human Mesenchymal Stem Cells: influence of different culture conditions on proliferative and myogenic capabilities
Testa, S.; Riera, C. S.; Fornetti, E.; Riccio, F.; Fuoco, C.; Bernardini, S.; Baldi, J.; Costantini, M.; Foddai, M. L.; Cannata, S.; Gargioli, C.
10.1101/2020.05.12.090746 — cell biology — Posted on 2020-05-13
3208 Protease Activity Profiling Via Programmable Phage Display
Roman-Melendez, G.; Venkataraman, T.; Monaco, D.; Larman, H. B.
10.1101/2020.05.11.089607 — molecular biology — Posted on 2020-05-13
3210 SUPER RESOLUTION MICROSCOPY AND DEEP LEARNING IDENTIFY ZIKA VIRUS REORGANIZATION OF THE ENDOPLASMIC RETICULUM
Long, R. K. M.; Moriarty, K. P.; Cardoen, B.; Gao, G.; Vogl, A. W.; Jean, F.; Hamarneh, G.; Nabi, I. R.
10.1101/2020.05.12.091611 — cell biology — Posted on 2020-05-13
3211 Flotillin-upregulation acts as an epithelial-mesenchymal transition driver by promoting sphingosine kinase 2-dependent AXL stabilization
Genest, M.; Comunale, F.; Rios-Morris, E.; Planchon, D.; Govindin, P.; Vacher, S.; Bieche, I.; Robert, B.; Schoenit, A.; Tashireva, L.; Gauthier-Rouviere, C.; Bodin, S.
10.1101/2020.05.12.090571 — cell biology — Posted on 2020-05-13
3214 Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b
Chan, L.-J.; Gandhirajan, A.; Carias, L. L.; Dietrich, M. H.; Vadas, O.; Visentin, R.; Franca, C. T.; Menant, S.; Soldati-Favre, D.; Mueller, I.; King, C. L.; Tham, W.-H.
10.1101/2020.05.12.091900 — microbiology — Posted on 2020-05-13
3215 A lineage-tracing tool to map the fate of hypoxic tumour cells
Vermeer, J. A. F.; Ient, J.; Markelc, B.; Kaeppler, J.; Barbeau, L. M. O.; Groot, A. J.; Muschel, R. J.; Vooijs, M. A.
10.1101/2020.03.03.974857 — cancer biology — Posted on 2020-05-13
3217 Shoot and root thermomorphogenesis are linked by a developmental trade-off
Gaillochet, C.; Burko, Y.; Platre, M. P.; Zhang, L.; Simura, J.; Kumar, V.; Ljung, K.; Chory, J.; Busch, W.
10.1101/2020.05.07.083246 — plant biology — Posted on 2020-05-13
3218 Retrograde transport defects in Munc18-1 null neurons explain abnormal Golgi morphology
van Berkel, A. A.; Santos, T. C.; Shaweis, H.; van Weering, J. R. T.; Toonen, R. F. G.; Verhage, M.
10.1101/2020.05.12.090811 — neuroscience — Posted on 2020-05-13
3220 Visualizing the dynamics of exported bacterial proteins with the chemogenetic fluorescent reporter FAST
Chekli, Y.; Peron-Cane, C.; Dell'Arciprete, D.; Allemand, J.-F.; Li, C.; GHIGO, J.-M.; Gautier, A.; Lebreton, A.; Desprat, N.; BELOIN, C.
10.1101/2020.05.12.090142 — microbiology — Posted on 2020-05-13
3222 Antibiotics may influence gut microbiome signaling to the brain in preterm neonates
Russell, J. T.; Ruoss, J. L.; de la Cruz, D.; Li, N.; Bazacliu, C.; Patton, L.; Lobean McKinley, K.; Garrett, T. J.; Polin, R. A.; Triplett, E. W.; Neu, J.
10.1101/2020.04.20.052142 — microbiology — Posted on 2020-05-13
3223 Expanding the Caenorhabditis elegans auxin-inducible degron system toolkit with internal expression and degradation controls and improved modular constructs for CRISPR/Cas9-mediated genome editing
Ashley, G.; Duong, T.; Levenson, M. T. .; Martinez, M. A. Q.; Hibshman, J. D.; Saeger, H. N.; Doonan, R.; Palmisano, N. J.; Martinez-Mendez, R.; Davidson, B.; Zhang, W.; Ragle, J. M.; Medwig-Kinney, T. N.; Sirota, S. S.; Goldstein, B.; Matus, D. Q.; Dickinson, D. J.; Reiner, D. J.; Ward, J. D.
10.1101/2020.05.12.090217 — genetics — Posted on 2020-05-13
3226 Gene expression and chromatin accessibility during progressive EMT and MET linked to dynamic CTCF engagement
Johnson, K. S.; Hussein, S.; Song, S.; Chakraborty, P.; Jolly, M. K.; Toneff, M.; Lin, Y.; Taube, J.
10.1101/2020.05.11.089110 — cell biology — Posted on 2020-05-13
3230 Mediocremonas mediterraneus, a New Member within the Developea
Weiler, B. A.; Sa, E.; Sieracki, M. E.; Massana, R.; del Campo, J.
10.1101/2020.05.12.090621 — microbiology — Posted on 2020-05-13
3233 A novel RNA virus, Macrobrachium rosenbergii Golda virus (MrGV), linked to mass mortalities of the larval giant freshwater prawn in Bangladesh
Hooper, C.; Debnath, P. P.; Biswas, S.; van Aerle, R.; Bateman, K. S.; Basak, S. K.; Rahman, M. M.; Mohan, C. V.; Rakibul Islam, H. M.; Ross, S.; Stentiford, G. D.; Currie, D.; Bass, D.
10.1101/2020.05.12.090258 — molecular biology — Posted on 2020-05-12
3237 Emergence of artemisinin-resistant Plasmodium falciparum with kelch13 C580Y mutations on the island of New Guinea
Miotto, O.; Sekihara, M.; Tachibana, S.-I.; Yamauchi, M.; Pearson, R. D.; Amato, R.; Goncalves, S.; Mehra, S.; Noviyanti, R.; Marfurt, J.; Auburn, S.; Price, R. N.; Mueller, I.; Ikeda, M.; Mori, T.; Hirai, M.; Tavul, L.; Hetzel, M.; Laman, M.; Barry, A.; Ringwald, P.; Ohashi, J.; Hombhanje, F.; Kwiatkowski, D. P.; Mita, T.
10.1101/621813 — microbiology — Posted on 2020-05-12
3238 Supramolecular assembly of the E. coli LdcI upon acid stress
Jessop, M.; Liesche, C.; Felix, J.; Desfosses, A.; Baulard, M.; Adam, V.; Fraudeau, A.; Huard, K.; Effantin, G.; Kleman, J.-P.; Bacia-Verloop, M.; Bourgeois, D.; Gutsche, I.
10.1101/2020.05.12.090381 — microbiology — Posted on 2020-05-13
3240 Linking phenotype, genotype and ecology: antimicrobial resistance in the zoonotic pathogen Streptococcus suis
Hadjirin, N. F.; Miller, E. L.; Murray, G. G. R.; Yen, P. L. K.; Phuc, H. D.; Wileman, T. M.; Hernandez-Garcia, J.; Williamson, S. M.; Parkhill, J.; Maskell, D. J.; Zhou, R.; Fittipaldi, N.; Gottschalk, M.; Tucker, A. .W.; Hoa, N. T.; Welch, J. J.; Weinert, L. A.
10.1101/2020.05.05.078493 — microbiology — Posted on 2020-05-13
3245 A new microcirculation culture method with a self-organized capillary network
Sugihara, K.; Yamaguchi, Y.; Usui, S.; Nashimoto, Y.; Hanada, S.; Kiyokawa, E.; Uemura, A.; Yokokawa, R.; Nishiyama, K.; Miura, T.
10.1101/2020.05.12.067165 — cell biology — Posted on 2020-05-13
3249 RootPainter: Deep Learning Segmentation of Biological Images with Corrective Annotation
Smith, A. G.; Han, E.; Petersen, J.; Olsen, N. A. F.; Giese, C.; Athmann, M.; Dresboll, D. B.; Thorup-Kristensen, K.
10.1101/2020.04.16.044461 — plant biology — Posted on 2020-05-12
3252 Genome-wide association study of school grades identifies a genetic overlap between language ability, psychopathology and creativity
Rajagopal, V. M.; Ganna, A.; Coleman, J. R.; Allegrini, A. G.; Voloudakis, G.; Grove, J.; Als, T. D.; Horsdal, H. T.; Petersen, L. V.; Appadurai, V.; Schork, A.; Buil, A.; Bulik, C.; Bybjerg-Grauholm, J.; Baekvad-Hansen, M.; Hougaard, D. M.; Mors, O.; Nordentoft, M.; Werge, T.; iPSYCH-Broad Consortium, ; Mortensen, P. B.; Breen, G.; Roussos, P.; Plomin, R.; Agerbo, E.; Borglum, A.; Demontis, D.
10.1101/2020.05.09.075226 — genomics — Posted on 2020-05-12
3253 Mutation landscape of SARS-CoV-2 reveals three mutually exclusive clusters of leading and trailing single nucleotide substitutions
Mishra, A.; Pandey, A. K.; Gupta, P.; Pradhan, P.; Dhamija, S.; Gomes, J.; Kundu, B.; Vivekanandan, P.; Menon, M. B.
10.1101/2020.05.07.082768 — genomics — Posted on 2020-05-12
3254 Androgen regulates SARS-CoV-2 receptor levels and is associated with severe COVID-19 symptoms in men
Ghazizadeh, Z.; Majd, H.; Richter, M.; Samuel, R.; Zekavat, S. M.; Asgharian, H.; Farahvashi, S.; Kalantari, A.; Ramirez, J.; Zhao, H.; Natarajan, P.; Goodarzi, H.; Fattahi, F.
10.1101/2020.05.12.091082 — cell biology — Posted on 2020-05-12
3256 Identification of biochemically neutral positions in liver pyruvate kinase
Martin, T. A.; Wu, T.; Tang, Q.; Dougherty, L. L.; Parente, D. J.; Swint-Kruse, L.; Fenton, A. W.
10.1101/632562 — biochemistry — Posted on 2020-05-12
3257 The ModelSEED Database for the integration of metabolic annotations and the reconstruction, comparison, and analysis of metabolic models for plants, fungi, and microbes
Seaver, S. M. D.; Liu, F.; Zhang, Q.; Jeffryes, J.; Faria, J. P.; Edirisinghe, J.; Mundy, M.; Chia, N.; Noor, E.; Beber, M. E.; Best, A. A.; DeJongh, M.; Kimbrel, J. A.; D'haeseleer, P.; Pearson, E.; Canon, S.; Wood-Charlson, E. M.; Cottingham, R. W.; Arkin, A. P.; Henry, C. S.
10.1101/2020.03.31.018663 — systems biology — Posted on 2020-05-12
3261 Enhanced aversive memory retrieval by chemogenetic activation of locus coeruleus norepinephrine neurons
Fukabori, R.; Iguchi, Y.; Takahashi, K.; Eifuku, S.; Tsuji, S.; Hazama, A.; Uchigashima, M.; Watanabe, M.; Mizuma, H.; Cui, Y.; Onoe, H.; Hikishima, K.; Yasoshima, Y.; Osanai, M.; Inagaki, R.; Fukunaga, K.; Nishijo, T.; Momiyama, T.; Benton, R.; Kobayashi, K.
10.1101/831313 — neuroscience — Posted on 2020-05-12
3262 Oculomotor inhibition precedes temporally expected auditory targets
Abeles, D.; Amit, R.; Tal-Perry, N.; Carrasco, M.; Yuval-Greenberg, S.
10.1101/2020.04.28.065839 — neuroscience — Posted on 2020-05-12
3263 Children's Hospital Los Angeles COVID-19 Analysis Research Database (CARD) - A Resource for Rapid SARS-CoV-2 Genome Identification Using Interactive Online Phylogenetic Tools
Shen, L.; Maglinte, D.; Ostrow, D.; Pandey, U.; Bootwalla, M.; Ryutov, A.; Govindarajan, A.; Ruble, D.; Han, J.; Triche, T. J.; Dien Bard, J.; Biegel, J. A.; Judkins, A. R.; Gai, X.
10.1101/2020.05.11.089763 — genomics — Posted on 2020-05-12
3264 Dissecting chronic myeloid leukaemia overlapping transcriptome with TIF-Seq2
Wang, J.; Li, B.; Marques, S.; Steinmetz, L. M.; Wei, W.; Pelechano, V.
10.1101/859488 — genomics — Posted on 2020-05-12
3265 Real-time dynamics of Plasmodium NDC80 reveals unusual modes of chromosome segregation during parasite proliferation
Zeeshan, M.; Pandey, R.; Ferguson, D. J. P.; Tromer, E. C.; Markus, R.; Abel, S.; Brady, D.; Daniel, E.; Stanway, R. R.; Bottrill, A. R.; Le Roch, K. G.; Holder, A. A.; Waller, R. F.; Guttery, D. S.; Tewari, R.
10.1101/767830 — cell biology — Posted on 2020-05-12
3266 CoV-Seq: SARS-CoV-2 Genome Analysis and Visualization
Liu, B.; Liu, K.; Zhang, H.; Zhang, L.; Bian, Y.; Huang, L.
10.1101/2020.05.01.071050 — bioinformatics — Posted on 2020-05-12
3267 Atypical spatial frequency dependence of visual metacognition among schizophrenia patients
Koizumi, A.; Hori, T.; Maniscalco, B.; Hayase, M.; Mishima, R.; Kawashima, T.; Miyata, J.; Aso, T.; Lau, H.; Takahashi, H.; Amano, K.
10.1101/853135 — neuroscience — Posted on 2020-05-12
3269 The influence of object-colour knowledge on emerging object representations in the brain
Teichmann, L.; Quek, G. L.; Robinson, A.; Grootswagers, T.; Carlson, T.; Rich, A.
10.1101/533513 — neuroscience — Posted on 2020-05-12
3270 Functional determinants of a small protein repressor controlling a broadly conserved bacterial sensor kinase
Yadavalli, S. S.; Goh, T.; Carey, J. N.; Malengo, G.; Vellappan, S.; Nickels, B. E.; Sourjik, V.; Goulian, M.; Yuan, J.
10.1101/438515 — microbiology — Posted on 2020-05-12
3273 Structural insights into the recognition of mono- and di-acetylated histones by the ATAD2B bromodomain
Lloyd, J. T.; McLaughlin, K.; Lubula, M. Y.; Gay, J. C.; Dest, A.; Gao, C.; Phillips, M.; Tonelli, M.; Cornilescu, G.; Marunde, M. R.; Evans, C. M.; Boyson, S. P.; Carlson, S.; Keogh, M.-C.; Markley, J. L.; Frietze, S.; Glass, K. C.
10.1101/263624 — biochemistry — Posted on 2020-05-12
3274 Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability
Brouwer, P.; Caniels, T.; van Straten, K.; Snitselaar, J.; Aldon, Y.; Bangaru, S.; Torres, J.; Okba, N.; Claireaux, M.; Kerster, G.; Bentlage, A.; van Haaren, M.; Guerra, D.; Burger, J.; Schermer, E.; Verheul, K.; van der Velde, N.; van der Kooi, A.; van Schooten, J.; van Breemen, M.; Bijl, T.; Sliepen, K.; Aartse, A.; Derking, R.; Bontjer, I.; Kootstra, N.; Wiersinga, J.; Vidarsson, G.; Haagmans, B.; Ward, A.; de Bree, G.; Sanders, R.; van Gils, M.
10.1101/2020.05.12.088716 — microbiology — Posted on 2020-05-12
3275 Antiviral options against SARS-CoV-2 infection
Ianevski, A.; Yao, R.; Fenstad, M. H.; Biza, S.; Zusinaite, E.; Lysvand, H.; Loeseth, K.; Lamndsem, V. M.; Malmring, J. F.; Oksenych, V.; Erlandsen, S. E.; Aas, P. A.; Hagen, L.; Pettersen, C. H.; Afset, J. E.; Nordbo, S. A.; Bjoras, M.; Kainov, D. E.
10.1101/2020.05.12.091165 — microbiology — Posted on 2020-05-12
3277 Characterization of neutralizing antibodies from a SARS-CoV-2 infected individual
Seydoux, E.; Homad, L. J.; MacCamy, A. J.; Parks, K. R.; Hurlburt, N. K.; Jennewein, M. F.; Akins, N. R.; Stuart, A. B.; Wan, Y.-H.; Feng, J.; Nelson, R.; Singh, S.; Cohen, K. W.; McElrath, J. M.; Englund, J. A.; Chu, H. Y.; Pancera, M.; McGuire, A. T.; Stamatatos, L.
10.1101/2020.05.12.091298 — immunology — Posted on 2020-05-12
3280 A small molecule that binds an RNA repeat expansion stimulates its decay via the exosome complex
Angelbello, A. J.; Benhamou, R. I.; Rzuczek, S. G.; Choudhary, S.; Tang, Z.; Chen, J. L.; Roy, M.; Wang, K. W.; Yildirim, I.; Jun, A. S.; Thornton, C. A.; Disney, M. D.
10.1101/2020.05.11.088427 — cell biology — Posted on 2020-05-12
3281 Structural variants at the BRCA1/2 loci are a common source of homologous repair deficiency in high grade serous ovarian carcinoma
Ewing, A.; Meynert, A.; Churchman, M.; Grimes, G. R.; Hollis, R. L.; Herrington, C. S.; Rye, T.; Bartos, C.; Croy, I.; Ferguson, M.; Lennie, M.; McGoldrick, T.; McPhail, N.; Siddiqui, N.; Dowson, S.; Glasspool, R.; Mackean, M.; Nussey, F.; McDade, B.; The Scottish Genomes Partnership, ; McMahon, L.; Matakidou, A.; Dougherty, B.; March, R.; Barrett, J. C.; McNeish, I. A.; Biankin, A. V.; Roxburgh, P.; Gourley, C.; Semple, C. A.
10.1101/2020.05.11.088278 — cancer biology — Posted on 2020-05-12
3285 Cancer Cell Intrinsic Expression of MHCII Regulates the Immune Microenvironment and Response to Anti-PD-1 Therapy in Lung Adenocarcinoma
Johnson, A. M.; Bullock, B. L.; Neuwelt, A. J.; Poczobutt, J. M.; Kaspar, R. E.; Li, H. Y.; Kwak, J. W.; Hopp, K.; Weiser-Evans, M. C. M.; Heasley, L. E.; Schenk, E. L.; Clambey, E. T.; Nemenoff, R. A.
10.1101/2020.01.09.900597 — cancer biology — Posted on 2020-05-12
3289 Exploring phenotyping plasticity for improving deficit irrigation and growth performance in maize
Urfan, M.; Hakla, H. R.; Sharma, S.; Sharma, M.; Khajuria, M.; Vyas, D.; Satbhai, S. B.; Pal, S.
10.1101/2020.05.12.087940 — plant biology — Posted on 2020-05-12
3290 Ppd-1 Remodels Spike Architecture by Regulating Floral Development in wheat
Liu, Y.; Zhang, L.; Melzer, M.; shen, L.; Wang, Z.; Sun, Z.; Schnurbusch, T.; Guo, Z.
10.1101/2020.05.11.087809 — plant biology — Posted on 2020-05-12
3292 Electrophysiological receptor mapping of GABA-A receptors
Shaw, A. D.; Chandler, H. L.; Hamandi, K.; Muthukumaraswamy, S. D.; Hammers, A.; Singh, K. D.
10.1101/2020.05.11.087726 — neuroscience — Posted on 2020-05-12
3298 Development of caecaloids to study host-pathogen interactions: new insights into immunoregulatory functions of Trichuris muris extracellular vesicles in the caecum
Duque-Correa, M. A.; Schreiber, F.; Rodgers, F. H.; Goulding, D.; Forrest, S.; White, R.; Buck, A.; Grencis, R. K.; Berriman, M.
10.1101/2020.05.11.087684 — immunology — Posted on 2020-05-12
3300 The complex optic lobe of dragonflies
Fabian, J. M.; el Jundi, B. M.; Wiederman, S. D.; O'Carroll, D. C.
10.1101/2020.05.10.087437 — neuroscience — Posted on 2020-05-12
3303 The study of the determinants controlling Arpp19 phosphatase-inhibitory activity reveals a new Arpp19/PP2A-B55 feedback loop
Labbe, J. C.; Vigneron, S.; Mechali, F.; Robert, P.; Genoud, C.; Goguet-Rubio, P.; Barthe, P.; Labesse, G.; Cohen-Gonsaud, M.; Castro, A.; Lorca, T.
10.1101/2020.05.11.087890 — developmental biology — Posted on 2020-05-12
3305 Deubiquitinating Enzyme Amino Acid Profiling Reveals a Class of Ubiquitin Esterases
Virdee, S.; De Cesare, V.; Carbajo Lopez, D.; Mabbitt, P. D.; Antico, O.; Wood, N. T.
10.1101/2020.05.11.087965 — biochemistry — Posted on 2020-05-12
3306 RippleNet: A Recurrent Neural Network for Sharp Wave Ripple (SPW-R) Detection
Hagen, E.; Chambers, A. R.; Einevoll, G. T.; Pettersen, K. H.; Enger, R.; Stasik, A. J.
10.1101/2020.05.11.087874 — neuroscience — Posted on 2020-05-12
3309 Connecting structure to function with the recovery of over 1000 high-quality activated sludge metagenome-assembled genomes encoding full-length rRNA genes using long-read sequencing
Singleton, C. M.; Petriglieri, F.; Kristensen, J. M.; Kirkegaard, R. H.; Michaelsen, T. Y.; Andersen, M. H.; Kondrotaite, Z.; Karst, S. M.; Dueholm, M. S.; Nielsen, P. H.; Albertsen, M.
10.1101/2020.05.12.088096 — microbiology — Posted on 2020-05-12
3310 Inhibition of 2-Hydroxyglutrate Elicits Metabolic-reprograming and Mutant IDH1 Glioma Immunity
Kadiyala, P.; Carney, S. V.; Gauss, J. C.; Garcia-Fabiani, M.; Nunez, F.; Nunez, F. M.; Alghamri, M.; Liu, Y.; Yu, M.; Li, D.; Edwards, M.; Moon, J. J.; Schwendeman, A.; Lowenstein, P. R.; Castro, M.
10.1101/2020.05.11.086371 — immunology — Posted on 2020-05-12
3319 Lumi-Map, a real-time luciferase bioluminescence screen of mutants combined with MutMap, reveals Arabidopsis genes involved in PAMP-triggered immunity
Kato, H.; Onai, K.; Abe, A.; Shimizu, M.; Takagi, H.; Tateda, C.; Utsushi, H.; Singkarabanit-Ogawa, S.; Kitakura, S.; Ono, E.; Zipfel, C.; Takano, Y.; Ishiura, M.; Terauchi, R.
10.1101/2020.05.11.086728 — plant biology — Posted on 2020-05-12
3320 Learning-induced plasticity in the barrel cortex is disrupted by inhibition of layer 4 somatostatin-containing interneurons
Dobrzanski, G.; Lukomska, A.; Zakrzewska, R.; Posluszny, A.; Kanigowski, D.; Urban-Ciecko, J.; Liguz-Lecznar, M.; Kossut, M.
10.1101/2020.05.11.087791 — neuroscience — Posted on 2020-05-12
3321 Metric and chronological time in human episodic memory
Evensmoen, H.; Rimol, L. M.; Rise, H. H.; Hansen, T. I.; Nili, H.; Winkler, A.; Haaberg, A. K.
10.1101/2020.05.11.084202 — neuroscience — Posted on 2020-05-12
3325 YeaZ: A convolutional neural network for highly accurate, label-free segmentation of yeast microscopy images
Dietler, N.; Minder, M.; Gligorovski, V.; Economou, A. M.; Joly, D. A. H. L.; Sadeghi, A.; Chan, C. H. M.; Kozinski, M.; Weigert, M.; Bitbol, A.-F.; Rahi, S. J.
10.1101/2020.05.11.082594 — bioinformatics — Posted on 2020-05-12
3326 COTAN: Co-expression Table Analysis for scRNA-seq data
Galfre', S. G.; Morandin, F.; Pietrosanto, M.; Cremisi, F.; Helmer-Citterich, M.
10.1101/2020.05.11.088062 — bioinformatics — Posted on 2020-05-12
3328 Huntington's disease-specific mis-splicing captured by human-mouse intersect-RNA-seq unveils pathogenic effectors and reduced splicing factors
Elorza, A.; Marquez, Y.; Cabrera, J. R.; Sanchez-Trincado, J. L.; Santos-Galindo, M.; Hernandez, I. H.; Diaz-Hernandez, J. I.; Garcia-Escudero, R.; Irimia, M.; Lucas, J. J.
10.1101/2020.05.11.086017 — neuroscience — Posted on 2020-05-12
3329 Processing of a spoken narrative in the human brain is shaped by family cultural background
Hakonen, M.; Ikaheimonen, A.; Hulten, A.; Kauttonen, J.; Koskinen, M.; Lin, F.-H.; Lowe, A.; Sams, M.; Jaaskelainen, I.
10.1101/2020.05.11.083931 — neuroscience — Posted on 2020-05-12
3332 Allelic diversity study of functional genes in East Africa bread wheat highlights opportunities for genetic improvement.
Wamalwa, M.; Tadesse, Z.; Muthui, L.; Yao, N.; Zegeye, H.; Randhawa, M.; Wanyera, R.; Uauy, C.; Shorinola, O.
10.1101/2020.05.11.088104 — genetics — Posted on 2020-05-12
3333 SIRT1 activity orchestrates ECM expression during hESC-chondrogenic differentiation through SOX5 and ARID5B
Smith, C. A.; Humphreys, P. A.; Bates, N.; Naven, M. A.; Cain, S. A.; Kimber, S. J.; Dvir Ginzbrg, M.
10.1101/2020.05.12.087957 — developmental biology — Posted on 2020-05-12
3335 The SARS-CoV-2 conserved macrodomain is a highly efficient ADP-ribosylhydrolase enzyme
Alhammad, Y. M. O.; Kashipathy, M. M.; Roy, A.; Johnson, D. K.; McDonald, P.; Battaile, K. P.; Gao, P.; Lovell, S. W.; Fehr, A. R.
10.1101/2020.05.11.089375 — biochemistry — Posted on 2020-05-12
3336 Local computational methods to improve the interpretability and analysis of cryo-EM maps
Kaur, S.; Gomez-Blanco, J.; Adinarayanan, S.; Khalifa, A.; Sanchez-Garcia, R.; Wrapp, D.; McLellan, J. S.; Bui, K. H.; Vargas, J.
10.1101/2020.05.11.088013 — biophysics — Posted on 2020-05-12
3337 Pericyte-specific vascular expression of SARS-CoV-2 receptor ACE2 - implications for microvascular inflammation and hypercoagulopathy in COVID-19 patients
He, L.; Mae, M. A.; Sun, Y.; Muhl, L.; Nahar, K.; Liebanas, E. V.; Fagerlund, M. J.; Oldner, A.; Liu, J.; Genove, G.; Pietila, R.; Zhang, L.; Xie, Y.; Liptidis, S.; Mocci, G.; Stritt, S.; Osman, A.; Anisimov, A.; Hemanthakumar, K. A.; Rasenen, M.; Bjorkegren, J.; Vanlandewijck, M.; Blomgren, K.; Hansson, E.; Makinen, T.; Peng, X.-R.; Arnold, T. D.; Alitalo, K.; Eriksson, L. I.; Lendahl, U.; Betsholtz, C.
10.1101/2020.05.11.088500 — pathology — Posted on 2020-05-12
3338 Sensorimotor hallucinationsin Parkinson's disease
Bernasconi, F.; Blondiaux, E.; Potheegadoo, J.; Stripeikyte, G.; Pagonabarraga, J.; Bejr-Kasem, H.; Bassolino, M.; Akselrod, M.; Martinez-Horta, S.; Sampedro, F.; Hara, M.; Horvath, J.; Franza, M.; Konik, S.; Bereau, M.; Ghika, J.-A.; Burkhard, P. R.; Van De Ville, D.; Faivre, N.; Rognini, G.; Krack, P.; Kulisevsky, J.; Blanke, O.
10.1101/2020.05.11.054619 — neuroscience — Posted on 2020-05-12
3339 Recognition memory via repetition suppression in mouse hippocampal dorsal CA2 pyramidal neurons expressing the vasopressin 1b receptor
Cymerblit-Sabba, A.; Stackmann, M.; Williams Avram, S.; Granovetter, M. C.; Cliz, N. I.; Pereira, F.; Smith, A. S.; Song, J.; Lee, H.-J.; Young, W. S.
10.1101/2020.05.11.078915 — neuroscience — Posted on 2020-05-12
3341 Spike-frequency adaptation provides a long short-term memory to networks of spiking neurons
Salaj, D.; Subramoney, A.; Kraisnikovic, C.; Bellec, G.; Legenstein, R.; Maass, W.
10.1101/2020.05.11.081513 — neuroscience — Posted on 2020-05-12
3342 High dimensional single-cell analysis reveals iNKT cell developmental trajectories and effector fate decision
Baranek, T.; Lebrigand, K.; de Amat Herbozo, C.; Gonzalez, L.; Bogard, G.; Dietrich, C.; Magnone, V.; Boisseau, C.; Jouan, Y.; Trottein, F.; Leite-de-Moraes, M.; Mallevaey, T.; Paget, C.
10.1101/2020.05.12.070425 — immunology — Posted on 2020-05-12
3343 Test-retest reliability of force plate-derived measures of reactive stepping
Saumur, T. M.; Mathur, S.; Nestico, J.; Perry, S. D.; Mochizuki, G.; Mansfield, A. M.
10.1101/2020.05.10.068957 — bioengineering — Posted on 2020-05-12
3344 Eating to dare - Nutrition impacts human risk decision and related brain function
Liu, L.; Artigas, S. O.; Ulrich, A.; Tardu, J.; Wilms, B.; Koletzko, B.; Schmid, S. M.; Park, S. Q.
10.1101/2020.05.10.085688 — neuroscience — Posted on 2020-05-12
3346 Changes in electrophysiological static and dynamic human brain functional architecture from childhood to late adulthood
Coquelet, N.; Wens, V.; Mary, A.; Niesen, M.; Puttaert, D.; Ranzini, M.; Vander Ghinst, M.; Bourguignon, M.; Peigneux, P.; Goldman, S.; Woolrich, M. W.; De Tiege, X.
10.1101/2020.05.11.047894 — neuroscience — Posted on 2020-05-12
3350 Silent dissemination of plasmid-borne tigecycline resistance gene tet(X6) in livestock-associated Acinetobacter towneri
Cheng, Y.; Chen, Y.; Liu, Y.; Song, J.; Guo, Y.; Zhou, Y.; Xiao, T.; Zhang, S.; Xu, H.; Chen, Y.-B.; Shan, T.; Xiao, Y.; Zhou, K.
10.1101/2020.05.08.085514 — genetics — Posted on 2020-05-12
3351 Seascape genomics reveals candidate molecular targets of heat stress adaptation in three coral species
Selmoni, O.; Lecellier, G.; Magalon, H.; Vigliola, L.; Benzoni, F.; Peignon, C.; Joost, S.; Berteaux-Lecellier, V.
10.1101/2020.05.12.090050 — evolutionary biology — Posted on 2020-05-12
3352 Nano-Emulsion Adjuvant Enhances Cross-presentation by Lipid Body Formation Independent of Glycolysis
Suresh, M.; Lee, W.; Kingstad-Bakke, B.; Paulson, B.; Larsen, A.; Overmyer, K.; Marinaik, C.; Dull, K.; Toy, R.; Vogel, G.; Mueller, K.; Tweed, K.; Walsh, A.; Russell, J.; Saha, K.; Reyes, L.; Skala, M.; Sauer, J.-D.; Shayakhmetov, D. M.; Coon, J.; Roy, K.
10.1101/2020.05.08.083790 — immunology — Posted on 2020-05-12
3353 Gut microbiota impairs insulin clearance during obesity
Foley, K. P.; Zlitni, S.; Duggan, B. M.; Barra, N.; Anhe, F. F.; Cavallari, J. F.; Henriksbo, B. D.; Chen, C. Y.; Huang, M.; Lau, T.; Schertzer, J. D.
10.1101/2020.05.08.083923 — physiology — Posted on 2020-05-12
3354 Bayesian transfer in a complex spatial localisation task
Kiryakova, R.; Aston, S.; Beierholm, U.; Nardini, M.
10.1101/716431 — neuroscience — Posted on 2020-05-12
3358 Observed but Never Experienced - Vicarious Learning of Fear Under Ecological Conditions
Szczepanik, M.; Kazmierowska, A. M.; Michałowski, J. M.; Wypych, M.; Olsson, A.; Knapska, E.
10.1101/2020.01.29.924720 — neuroscience — Posted on 2020-05-12
3359 A systematic survey of PRMT interactomes reveals the key roles of arginine methylation in the global control of RNA splicing and translation
Wei, H.-H.; Fan, X.-J.; Hu, Y.; Tian, X.-X.; Guo, M.; Fang, Z.-Y.; Wu, P.; Gao, S.-X.; Peng, C.; Yang, Y.; Wang, Z.
10.1101/746529 — molecular biology — Posted on 2020-05-12
3360 Stable task information from an unstable neural population
Rule, M. E.; Loback, A.; Raman, D. V.; Driscoll, L. N.; Harvey, C. D.; O'Leary, T.
10.1101/796334 — neuroscience — Posted on 2020-05-12
3362 Variability within rare cell states enables multiple paths towards drug resistance
Emert, B.; Cote, C.; Torre, E. A.; Dardani, I. P.; Jiang, C.; Jain, N.; Shaffer, S. M.; Raj, A.
10.1101/2020.03.18.996660 — systems biology — Posted on 2020-05-12
3363 SUMOylation of rice DELLA SLR1 modulates transcriptional responses and improves yield under salt stress
Goncalves, N. M.; Fernandes, T.; Nunes, C.; Rosa, M. T. G.; Matiolli, C. C.; Rodrigues, M. A. A.; Barros, P. M.; Oliveira, M. M.; Abreu, I. A.
10.1101/2020.03.10.986224 — plant biology — Posted on 2020-05-12
3366 HCR-FlowFISH: A flexible CRISPR screening method to identify cis-regulatory elements and their target genes
Reilly, S. K.; Gosai, S. J.; Guiterrez, A.; Ulirsch, J. C.; Kanai, M.; Berenzy, D.; Kales, S.; Butler, G. B.; Gladden-Young, A.; Finucane, H. K.; Sabeti, P. C.; Tewhey, R.
10.1101/2020.05.11.078675 — genomics — Posted on 2020-05-12
3369 CryoEM Structure of CtBP2 Confirms Tetrameric Architecture
Jecrois, A. M.; Dcona, M. M.; Deng, X.; Bandyopadhyay, D.; Grossman, S. R.; Schiffer, C. A.; Royer, W. E.
10.1101/2020.04.06.027573 — biochemistry — Posted on 2020-05-12
3373 Minimal genome-wide human CRISPR-Cas9 library
Goncalves, E.; Thomas, M.; Behan, F. M.; Picco, G.; Pacini, C.; Allen, F.; Sharma, M.; Jackson, D. A.; Price, S.; Beaver, C. M.; Dovey, O.; Parry-Smith, D.; Iorio, F.; Parts, L.; Yusa, K.; Garnett, M. J.
10.1101/848895 — genomics — Posted on 2020-05-12
3377 An active chromatin interactome in relevant cell lines elucidates biological mechanisms at genetic risk loci for dermatological traits
Shi, C.; Ray-Jones, H.; Ding, J.; Duffus, K.; Fu, Y.; Gaddi, V. P.; Gough, O.; Hankinson, J.; Martin, P.; Mcgovern, A.; Yarwood, A.; Gaffney, P.; Eyre, S.; Rattray, M.; Warren, R.; Orozco, G.
10.1101/2020.03.05.973271 — genomics — Posted on 2020-05-12
3378 Common fragile sites are characterised by faulty condensin loading after replication stress
Boteva, L.; Nozawa, R.-S.; Naughton, C.; Samejima, K.; Earnshaw, W.; Gilbert, N.
10.1101/508713 — molecular biology — Posted on 2020-05-12
3379 Tracing animal genomic evolution with the chromosomal-level assembly of the freshwater sponge Ephydatia muelleri
Kenny, N. J.; Francis, W. R.; Rivera-Vicens, R. E.; Juravel, K.; de Mendoza, A.; Diez-Vives, C.; Lister, R.; Bezares-Calderon, L.; Grombacher, L.; Roller, M.; Barlow, L. D.; Camilli, S.; Ryan, J. F.; Wörheide, G.; Hill, A. L.; Riesgo, A.; Leys, S.
10.1101/2020.02.18.954784 — evolutionary biology — Posted on 2020-05-12
3381 Drug-tolerant idling melanoma cells exhibit theory-predicted metabolic low-low phenotype
Jia, D.; Paudel, B.; Hayford, C. E.; Hardeman, K.; Levine, H.; Onuchic, J. N.; Quaranta, V.
10.1101/809889 — systems biology — Posted on 2020-05-12
3382 Modular and distinct PlexinA4/Farp2/Rac1 signaling controls dendrite morphogenesis
Danelon, V.; Goldner, R.; Martinez, E.; Gokhman, I.; Wang, K.; Yaron, A.; Tran, T. S.
10.1101/2020.01.15.908434 — neuroscience — Posted on 2020-05-12
3383 HIV-1 and HIV-2 differentially regulate NF-κB activity during the late stages of the replication cycle through BST-2/tetherin antagonism
Dufrasne, F. E.; Dessilly, G.; Lucchetti, M.; Soumillion, K.; Ngyuvula, E.; Ruelle, J.; Tafforeau, L.; Sanou, M.; Kabamba-Mukadi, B.
10.1101/2020.05.11.088385 — microbiology — Posted on 2020-05-12
3385 Mendelian randomisation for mediation analysis: current methods and challenges for implementation
Carter, A. R.; Sanderson, E.; Hammerton, G.; Richmond, R.; Davey Smith, G.; Heron, J.; Taylor, A.; Davies, N. M.; Howe, L. D.
10.1101/835819 — genetics — Posted on 2020-05-12
3389 Joint probabilistic modeling of paired transcriptome and proteome measurements in single cells
Gayoso, A.; Steier, Z.; Lopez, R.; Regier, J.; Nazor, K. L.; Streets, A.; Yosef, N.
10.1101/2020.05.08.083337 — bioinformatics — Posted on 2020-05-12
3390 The BRPF1 bromodomain is a molecular reader of di-acetyllysine
Obi, J. O.; Lubula, M. Y.; Cornilescu, G.; Henrickson, A.; McGuire, K.; Evans, C. M.; Phillips, M.; Boyson, S. P.; Demeler, B.; Markley, J. L.; Glass, K. C.
10.1101/2020.02.13.948091 — biochemistry — Posted on 2020-05-12
3393 Measuring Sequences of Representations with Temporally Delayed Linear Modelling
Liu, Y.; Dolan, R.; Penagos-Vargas, H. L.; Kurth-Nelson, Z.; Behrens, T. E. J.
10.1101/2020.04.30.066407 — neuroscience — Posted on 2020-05-12
3394 Infection with CagA+ Helicobacter pylori induces epithelial to mesenchymal transition in human cholangiocytes
Thanaphongdecha, P.; Speigh, S.; Tanno, W. I.; Mann, V. H.; Chamgramol, Y.; Pairojkul, C.; Fox, J. G.; Suttiprapa, S.; Sripa, B.; Brindley, P. J.
10.1101/2020.04.28.066324 — molecular biology — Posted on 2020-05-12
3397 Shape matters: the relationship between cell geometry and diversity in phytoplankton
Ryabov, A.; Kerimoglu, O.; Litchman, E.; Olenina, I.; Roselli, L.; Basset, A.; Stanca, E.; Blasius, B.
10.1101/2020.02.06.937219 — ecology — Posted on 2020-05-12
3399 Discovering biomarkers of chemotherapy resistance using in vitro evolution in haploid human cells
Jado, J. C.; Dow, M.; Carolino, K.; Fonseca, G.; Ideker, T.; Carter, H.; Winzeler, E.
10.1101/2020.03.17.982181 — cancer biology — Posted on 2020-05-12
3402 Network analysis prioritizes DEWAX and ICE1 as the candidate genes for two major eQTL hotspots in seed germination
Hartanto, M.; Joosen, R. V. L.; Snoek, B. L.; Willems, L. A. J.; Sterken, M. G.; de Ridder, D.; Hilhorst, H. W. M.; Ligterink, W.; Nijveen, H.
10.1101/2020.04.29.050567 — plant biology — Posted on 2020-05-12
3406 Evolution of resistance to fluoroquinolones by dengue virus serotype 4 provides insight into mechanism of action and consequences for viral fitness
Scroggs, S. L. P.; Gass, J. T.; Chinnasamy, R.; Widen, S. G.; Azar, S. R.; Rossi, S. L.; Arterburn, J. B.; Vasilakis, N.; Hanley, K. A.
10.1101/2020.05.11.088690 — evolutionary biology — Posted on 2020-05-12
3411 Cryptococcus neoformans evades pulmonary immunity by modulating xylose precursor transport
Li, L. X.; Hole, C. R.; Rangel-Moreno, J.; Khader, S. A.; Doering, T. L.
10.1101/741017 — microbiology — Posted on 2020-05-11
3413 Phage infection mediates inhibition of bystander bacteria
Chatterjee, A.; Willett, J. L. E.; Dunny, G. M.; Duerkop, B. A.
10.1101/2020.05.11.077669 — microbiology — Posted on 2020-05-11
3415 Chromatin arranges in chains of mesoscale domains with nanoscale functional topography independent of cohesin
Miron, E.; Oldenkamp, R.; Brown, J. M.; Pinto, D. M.; Xu, C. S.; Faria, A. R.; Shaban, H. A.; Rhodes, J. D.; Innocent, C.; de Ornellas, S.; Hess, H.; Buckle, V.; Schermelleh, L.
10.1101/566638 — genomics — Posted on 2020-05-11
3420 Historical population declines prompted significant genomic erosion in the northern and southern white rhinoceros (Ceratotherium simum)
Sanchez Barreiro, F.; Gopalakrishnan, S.; Ramos-Madrigal, J.; Westbury, M. V.; de Manuel, M.; Margaryan, A.; Ciucani, M. M.; Vieira, F. G.; Patramanis, Y.; Kalthoff, D.; Timmons, Z.; Sicheritz-Ponten, T.; Dalen, L.; Ryder, O. A.; Zhang, G.; Marques-Bonet, T.; Moodley, Y.; Gilbert, M. T. P.
10.1101/2020.05.10.086686 — evolutionary biology — Posted on 2020-05-11
3422 A systems genetics approach reveals environment-dependent associations between SNPs, protein co-expression and drought-related traits in maize
Blein-Nicolas, M.; Negro, S. S.; Balliau, T.; Welcker, C.; Cabrera-Bosquet, L.; Nicolas, S. D.; Charcosset, A.; Zivy, M.
10.1101/636514 — systems biology — Posted on 2020-05-11
3423 Dicer-like 5 deficiency confers temperature-sensitive male sterility in maize
Teng, C.; Zhang, H.; Hammond, R.; Huang, K.; Meyers, B.; Walbot, V.
10.1101/498410 — plant biology — Posted on 2020-05-11
3425 The genomic and epigenomic evolutionary history of papillary renal cell carcinomas
Zhu, B.; Poeta, M. L.; Costantini, M.; Zhang, T.; Shi, J.; Sentinelli, S.; Zhao, W.; Pompeo, V.; Cardelli, M.; Alexandrov, B. S.; Otlu, B.; Hua, X.; Jones, K.; Brodie, S.; Toro, J. R.; Yeager, M.; Wang, M.; Hicks, B.; Alexandrov, L. B.; Brown, K. M.; Wedge, D. C.; Chanock, S.; Fazio, V. M.; Gallucci, M.; Landi, M. T.
10.1101/478156 — genomics — Posted on 2020-05-11
3426 Evidence for strong mutation bias towards, and selection against, T/U content in SARS-CoV2: implications for attenuated vaccine design.
Rice, A. M.; Castillo Morales, A.; Ho, A. T.; Mordstein, C.; Mühlhausen, S.; Watson, S.; Cano, L.; Young, B.; Kudla, G.; Hurst, L. D.
10.1101/2020.05.11.088112 — evolutionary biology — Posted on 2020-05-11
3429 Learning hierarchical sequence representations across human cortex and hippocampus
Henin, S.; Turk-Browne, N.; Friedman, D.; Liu, A.; Dugan, P.; Flinker, A.; Doyle, W.; Devinsky, O.; Melloni, L.
10.1101/583856 — neuroscience — Posted on 2020-05-11
3430 Rapid isolation of potent SARS-CoV-2 neutralizing antibodies and protection in a small animal model
Rogers, T. F.; Zhao, F.; Huang, D.; Beutler, N.; Abbott, R. K.; Callaghan, S.; Garcia, E.; He, W.-t.; Hurtado, J.; Limbo, O.; Parren, M.; Peng, L.; Ricketts, J.; Ricciardi, M. K.; Smith, C.; Song, G.; Woehl, J.; Yang, L.; Rawlings, S.; Smith, D. M.; Nemazee, D.; Teijaro, J. R.; Voss, J. E.; Andrabi, R.; Briney, B.; Landais, E.; Sok, D.; Jardine, J. G.; Burton, D.
10.1101/2020.05.11.088674 — immunology — Posted on 2020-05-11
3432 A chemical screen identifies a link between lipid metabolism and mRNA translation
Fernandez-Capetillo, O.; Corman, A.; Kanellis, D. C.; Haggblad, M.; Lafarga, V.; Bartek, J.; Carreras-Puigvert, J.
10.1101/2020.05.11.088005 — molecular biology — Posted on 2020-05-11
3433 A Rapid, Cost-Effective Tailed Amplicon Method for Sequencing SARS-CoV-2
Gohl, D. M.; Garbe, J.; Grady, P.; Daniel, J.; Watson, R. H. B.; Auch, B.; Nelson, A.; Yohe, S.; Beckman, K. B.
10.1101/2020.05.11.088724 — genomics — Posted on 2020-05-11
3434 Nance-Horan Syndrome-like 1 protein negatively regulates Scar/WAVE-Arp2/3 activity and inhibits lamellipodia stability and cell migration.
Law, A.-L.; Jalal, S.; Mosis, F.; Pallett, T.; Guni, A.; Brayford, S.; Yolland, L.; Marcotti, S.; Levitt, J.; Poland, S.; Rowe-Sampson, M.; Jandke, A.; Koechl, R.; Pula, G.; Ameer-Beg, S. M.; Stramer, B. M.; Krause, M.
10.1101/2020.05.11.083030 — cell biology — Posted on 2020-05-11
3440 Cellular water analysis in T cells reveals a switch from metabolic water gain to water influx
Saragovi, A.; Zilberman, T.; Yasur, G.; Turjeman, K.; Abramovich, I.; Kuchersky, M.; Gottlieb, E.; Barenholz, Y.; Berger, M.
10.1101/2020.05.11.087767 — biochemistry — Posted on 2020-05-11
3442 Skin protective effects of RM191A, a novel superoxide dismutase mimetic
Shariev, A.; Laos, A. J.; Lai, D.; Hua, S.; Zinger, A.; Mcrae, C. R.; Casbolt, L. S.; Combes, V.; Hung, T.-t.; Dixon, K. M.; Thordarson, P.; Mason, R. S.; Das, A.
10.1101/2020.05.10.086694 — physiology — Posted on 2020-05-11
3443 Mitochondrial fission is a critical modulator of mutant APP-induced neural toxicity
Shields, L. Y.; Li, H.; Nguyen, K.; Kim, H.; Doric, Z.; Gill, T. M.; Haddad, D.; Vossel, K.; Calvert, M.; Nakamura, K.
10.1101/2020.05.10.087346 — neuroscience — Posted on 2020-05-11
3444 An Atlas of Gene Regulatory Elements in Adult Mouse Cerebrum
Li, Y.; Preissl, S.; Hou, X.; Zhang, z.; Zhang, K.; Fang, R.; Qiu, Y.; Poirion, O.; Li, B.; Yan, Y.; Liu, H.; Wang, X.; Han, J. Y.; Lucero, J.; Kuan, S.; Gorkin, D.; Nunn, M.; Mukamel, E. A.; Behrens, M. M.; Ecker, J. R.; Ren, B.
10.1101/2020.05.10.087585 — neuroscience — Posted on 2020-05-11
3445 Longitudinal profiles of dietary and microbial metabolites in formula- and breastfed infants
Sillner, N.; Walker, A.; Lucio, M.; Maier, T. V.; Bazanella, M.; Rychlik, M.; Haller, D.; Schmitt-Kopplin, P.
10.1101/2020.05.11.086546 — biochemistry — Posted on 2020-05-11
3446 Intra-dimer cooperativity between the active site cysteines during the oxidation of peroxiredoxin 2
Peskin, A. V.; Meotti, F. C.; de Souza, L. F.; Anderson, R. F.; Winterbourn, C. C.; Salvador, A.
10.1101/2020.05.11.087908 — biochemistry — Posted on 2020-05-11
3449 Metabolomic signatures of coral bleaching history
Roach, T. N. F.; Dilworth, J.; Martin H., C.; Jones, A. D.; Quinn, R. A.; Drury, C.
10.1101/2020.05.10.087072 — ecology — Posted on 2020-05-11
3450 Trajectory analysis of cardiovascular phenotypes from biobank data uncovers novel genetic associations
Pottinger, T. D.; Pesce, L. L.; Gacita, A.; Montefiori, L.; Hodge, N.; Kearns, S.; Salamone, I. M.; Pacheco, J. A.; Rasmussen-Torvik, L. J.; Smith, M. E.; Chisholm, R.; Nobrega, M. A.; McNally, E. M.; Puckelwartz, M. J.
10.1101/2020.05.10.087130 — genomics — Posted on 2020-05-11
3454 A rapid, low cost, and highly sensitive SARS-CoV-2 diagnostic based on whole genome sequencing
Glenn St Hilaire, B.; Durand, N. C.; Mitra, N.; Godinez Pulido, S.; Mahajan, R.; Blackburn, A.; Colaric, Z. L.; Theisen, J. W. M.; Weisz, D.; Dudchenko, O.; Gnirke, A.; Rao, S. S. P.; Kaur, P.; Aiden, E. L.; Aiden, A. P.
10.1101/2020.04.25.061499 — genomics — Posted on 2020-05-11
3455 Genome-wide data inferring the evolution and population demography of the novel pneumonia coronavirus (SARS-CoV-2)
Fang, B.; Liu, L.; Yu, X.; Li, X.; Ye, G.; Xu, J.; Zhang, L.; Zhan, F.; Liu, G.; Pan, T.; Shu, Y.; Jiang, Y.
10.1101/2020.03.04.976662 — evolutionary biology — Posted on 2020-05-11
3460 Removal of repressive histone marks creates epigenetic memory of recurring heat in Arabidopsis
Yamaguchi, N.; Matsubara, S.; Yoshimizu, K.; Seki, M.; Hamada, K.; Kamitani, M.; Kurita, Y.; Inagaki, S.; Suzuki, T.; Gan, E.-S.; To, T.; Kakutani, T.; Nagano, A. J.; Satake, A.; Ito, T.
10.1101/2020.05.10.086611 — plant biology — Posted on 2020-05-11
3464 Mapping fetal brain development based on automated segmentation and 4D brain atlasing
Li, H.; Yan, G.; Luo, W.; Liu, T.; Wang, Y.; Liu, R.; Zheng, W.; Zhang, Y.; Li, K.; Zhao, L.; Limperopoulos, C.; Zou, Y.; Wu, D.
10.1101/2020.05.10.085381 — neuroscience — Posted on 2020-05-11
3465 Enisamium is a small molecule inhibitor of the influenza A virus and SARS-CoV-2 RNA polymerases
Walker, A.; Fan, H.; Keown, J. R.; Margitich, V.; Grimes, J. M.; Fodor, E.; te Velthuis, A. J.
10.1101/2020.04.21.053017 — microbiology — Posted on 2020-05-11
3467 SARS-CoV-2 spike protein predicted to form stable complexes with host receptor protein orthologues from mammals, but not fish, birds or reptiles
Lam, S. D.; Bordin, N.; Waman, V. P.; Scholes, H. M.; Ashford, P.; Sen, N.; van Dorp, L.; Rauer, C.; Dawson, N. L.; Pang, C. S.; Abbasian, M.; Sillitoe, I.; Edwards, S. J.; Fraternali, F.; Lees, J. G.; Santini, J. M.; Orengo, C. A.
10.1101/2020.05.01.072371 — bioinformatics — Posted on 2020-05-11
3468 Stress granules display bistable dynamics modulated by Cdk
Yahya, G.; Perez, A. P.; Mendoza, M. B.; Parisi, E.; Moreno, D. F.; Gallego, C.; Aldea, M.
10.1101/2020.05.08.083782 — cell biology — Posted on 2020-05-11
3470 A series of five population-specific Indian brain templates and atlases spanning ages 6 to 60 years
Holla, B.; Taylor, P. A.; Glen, D. R.; Lee, J. A.; Vaidya, N.; Mehta, U. M.; Venkatasubramanian, G.; Pal, P.; Saini, J.; Rao, N. P.; Ahuja, C.; Kuriyan, R.; Krishna, M.; Basu, D.; Kalyanram, K.; Chakrabarti, A.; Orfanos, D. P.; Barker, G. J.; Cox, R. W.; Schumann, G.; Bharath, R. D.; Benegal, V.
10.1101/2020.05.08.077172 — neuroscience — Posted on 2020-05-11
3471 Genome wide association study in 3,173 outbred rats identifies multiple loci for body weight, adiposity, and fasting glucose
Chitre, A. S.; Polesskaya, O.; Holl, K.; Gao, J.; Cheng, R.; Garcia Martinez, A.; George, T.; Gileta, A. F.; Han, W.; Horvath, A.; Hughson, A.; Ishiwari, K.; King, C. P.; Lamparelli, A.; Versaggi, C. L.; Martin, C.; St. Pierre, C. L.; Tripi, J. A.; Wang, T.; Bimschleger, H.; Chen, H.; Flagel, S. B.; Meyer, P.; Richards, J.; Robinson, T. E.; Palmer, A. A.; Solberg Woods, L. C.
10.1101/422428 — genetics — Posted on 2020-05-11
3473 Endoglycan plays a role in axon guidance and neuronal migration by negatively regulating cell-cell adhesion
Baeriswyl, T.; Dumoulin, A.; Schaettin, M.; Tsapara, G.; Niederkofler, V.; Helbling, D.; Aviles, E.; Frei, J. A.; Wilson, N. H.; Gesemann, M.; Stoeckli, E. T.
10.1101/425207 — neuroscience — Posted on 2020-05-11
3475 Analyzing the neuroglial brainstem circuits for respiratory chemosensitivity in freely moving mice
Bhandare, A.; van de Wiel, J.; Roberts, R.; Braren, I.; Huckstepp, R.; Dale, N.
10.1101/492041 — neuroscience — Posted on 2020-05-11
3477 Year-to-year crop shifts promote weed diversity in tropical permanent rainfed cultivation
Neyret, M.; de Rouw, A.; Colbach, N.; Robain, H.; Soulileuth, B.; Valentin, C.
10.1101/2020.03.12.988469 — ecology — Posted on 2020-05-11
3478 Clearance of senescent cells during cardiac ischemia-reperfusion injury improves heart recovery following myocardial infarction
Dookun, E.; Walaszczyk, A.; Redgrave, R.; Palmowski, P.; Tual-Chalot, S.; Suwana, A.; Chapman, J.; Jirkovsky, E.; Donastorg, L.; Gill, E.; Santin, Y.; Yausep, o. E.; Mialet-Perez, J.; Owens, W. A.; Grieve, D. G.; Spyridopoulos, I.; Taggart, M.; Arthur, H.; Passos, J. F.; Richardson, G. D.
10.1101/2020.04.28.065789 — cell biology — Posted on 2020-05-11
3480 Network analysis prioritizes DEWAX and ICE1 as the candidate genes for two major eQTL hotspots in seed germination
Hartanto, M.; Joosen, R. V. L.; Snoek, B. L.; Willems, L. A. J.; Sterken, M. G.; de Ridder, D.; Hilhorst, H. W. M.; Ligterink, W.; Nijveen, H.
10.1101/2020.04.29.050567 — plant biology — Posted on 2020-05-11
3481 In-depth characterization of layer 5 output neurons of the primary somatosensory cortex innervating the mouse dorsal spinal cord
Frezel, N.; Platonova, E.; Voigt, F.; Mateos, J. M.; Kastli, R.; Ziegler, U.; Karayannis, T.; Helmchen, F.; Wildner, H.; Zeilhofer, H. U.
10.1101/2020.04.02.021311 — neuroscience — Posted on 2020-05-11
3482 Myosin-X is required for integrin activation at filopodia tips
Miihkinen, M.; Grönloh, M. L. B.; Vihinen, H.; Jokitalo, E.; Goult, B. T.; Ivaska, J.; Jacquemet, G.
10.1101/2020.05.05.078733 — cell biology — Posted on 2020-05-11
3484 Epigenetic aging of classical monocytes from healthy individuals
Shchukina, I.; Bagaitkar, J.; Shpynov, O.; Loginicheva, E.; Porter, S.; Mogilenko, D. A.; Wolin, E.; Collins, P.; Demidov, G.; Artomov, M.; Zaitsev, K.; Sidorov, S.; Camell, C.; Bambouskova, M.; Arthur, L.; Swain, A.; Panteleeva, A.; Dievskii, A.; Kurbatsky, E.; Tsurinov, P.; Chernyatchik, R.; Dixit, V. D.; Jovanovic, M.; Stewart, S. A.; Daly, M. J.; Dmitriev, S.; Oltz, E. M.; Artyomov, M. N.
10.1101/2020.05.10.087023 — systems biology — Posted on 2020-05-11
3488 Increased p53 signaling impairs neural differentiation causing HUWE1-promoted intellectual disabilities
Aprigliano, R.; Bradamante, S.; Mihaljevic, B.; Wang, W.; Fordyce Martin, S. L.; Bordin, D. L.; Bosshard, M.; Montaldo, N. P.; Peng, Y.; Alexov, E.; Skinner, C.; Bjoras, M.; Schwartz, C. E.; Van Loon, B.
10.1101/2020.05.10.087296 — cell biology — Posted on 2020-05-11
3491 Impact of industrial production system parameters on chicken microbiomes: mechanisms to improve performance and reduce Campylobacter
McKenna, A.; Ijaz, U. Z.; Kelly, C.; Linton, M.; Sloan, W. T.; Green, B. D.; Lavery, U.; Dorrell, N.; Wren, B. W.; Richmond, A.; Corcionivoschi, N.; Gundogdu, O.
10.1101/2020.05.10.084251 — microbiology — Posted on 2020-05-11
3495 Satellite glial cells promote regenerative growth in sensory neurons
Avraham, O.; Deng, P.-Y.; Jones, S.; Kuruvilla, R.; Semenkovich, C. F.; Klyachko, V. A.; Cavalli, V.
10.1101/2019.12.13.874669 — neuroscience — Posted on 2020-05-11
3497 Environmental RNA interference in two-spotted spider mite, Tetranychus urticae, reveals dsRNA processing requirements for efficient RNAi response
Bensoussan, N.; Dixit, S.; Tabara, M.; Letwin, D.; Milojevic, M.; Antonacci, M.; Jin, P.; Arai, Y.; Bruinsma, K.; Suzuki, T.; Fukuhara, T.; Zhurov, V.; Geibel, S.; Nauen, R.; Grbic, M.; Grbic, V.
10.1101/2020.05.10.087429 — molecular biology — Posted on 2020-05-11
3498 A cross-scale assessment of productivity-diversity relationships
Craven, D.; van der Sande, M.; Meyer, C.; Gerstner, K.; Bennett, J. M.; Giling, D. P.; Hines, J.; Phillips, H. R. P.; May, F.; Bannar-Martin, K.; Chase, J.; Keil, P.
10.1101/769232 — ecology — Posted on 2020-05-11
3502 Experimental and computational study on motor control and recovery after stroke: towards a constructive loop betweenexperimental and virtual embodiedneuroscience
Allegra Mascaro, A. L.; Falotico, E.; Petkoski, S.; Pasquini, M.; Vannucci, L.; Tort-Colet, N.; Conti, E.; Resta, F.; Spalletti, C.; Ramalingasetty, S. T.; von Arnim, A.; Formento, E.; Angelidis, E.; Blixhavn, C. H.; Leergaard, T. B.; Caleo, M.; Destexhe, A.; Ijspeert, A.; Micera, S.; Laschi, C.; Jirsa, V.; Gewaltig, M. O.; Pavone, F.
10.1101/2020.04.22.019661 — neuroscience — Posted on 2020-05-10
3503 Identification of MAZ as a novel transcription factor regulating erythropoiesis
Vernimmen, D.; Deen, D.; Butter, F.; Holland, M. L.; Samara, V.; Sloane-Stanley, J. A.; Ayyub, H.; Mann, M.; Garrick, D.
10.1101/2020.05.10.087254 — molecular biology — Posted on 2020-05-10
3515 Multiplexed in situ protein imaging using DNA-barcoded antibodies withextended hybridization chain reactions
Wang, Y.; Zeng, Y.; Saka, S. K.; Xie, W.; Goldaracena, I.; Kohman, R. E.; Yin, P.; Church, G. M.
10.1101/274456 — cell biology — Posted on 2020-05-10
3516 Binding partners regulate unfolding of myosin VI to activate the molecular motor
dos Santos, A.; Fili, N.; Hari-Gupta, Y.; Gough, R. E.; Wang, L.; Martin-Fernandez, M. L.; Arron, J.; Waite, E.; Chew, T. L.; Toseland, C. P.
10.1101/2020.05.10.079236 — biophysics — Posted on 2020-05-10
3517 A causal role for estradiol in human reinforcement learning
Veselic, S.; Jocham, G.; Gausterer, C.; Wagner, B.; Ressler, M.; Lanzenberger, R.; Lamm, C.; Eisenegger, C.; Vermeer, A. L.
10.1101/2020.02.18.954982 — neuroscience — Posted on 2020-05-10
3518 Potential modes of COVID-19 transmission from human eye revealed by single-cell atlas
Hamashima, K.; Gautam, P.; Lau, K. A.; Khiong, C. W.; Blenkinsop, T. A.; Li, H.; Loh, Y. H.
10.1101/2020.05.09.085613 — genomics — Posted on 2020-05-10
3520 Synthetic Maturation of Multilineage Human Liver Organoids via Genetically Guided Engineering
Velazquez, J. J.; LeGraw, R.; Moghadam, F.; Tan, Y.; Kilbourne, J.; Hislop, J.; Liu, S.; Cats, D.; Chuva de Sousa Lopes, S. M.; Plaisier, C.; Cahan, P.; Kiani, S.; Ebrahimkhani, M. R.
10.1101/2020.05.10.087445 — bioengineering — Posted on 2020-05-10
3522 Chemoinformatic-guided engineering of polyketide synthases
Zargar, A.; Lal, R.; Valencia, L.; Wang, J.; Backman, T.; Cruz-Morales, P.; Kothari, A.; Werts, M.; Wong, A.; Bailey, C. B.; Loubat, A.; Liu, Y.; Chen, Y.; Benites, V.; Chang, S.; Hernandez, A. C.; Barajas, J. F.; Thompson, M.; Barcelos, C.; Anayah, R.; Garcia-Martin, H.; Mukhopadhyay, A.; Petzold, C. J.; Baidoo, E. E.; Katz, L.; Keasling, J. D.
10.1101/805671 — biochemistry — Posted on 2020-05-10
3524 Germline mutagenesis of Nasonia vitripennis through ovarian delivery of CRISPR-Cas9 ribonucleoprotein
Chaverra-Rodriguez, D.; Dalla Benetta, E.; Heu, C. C.; Rasgon, J.; Ferree, P. M.; Akbari, O. S.
10.1101/2020.05.10.087494 — molecular biology — Posted on 2020-05-10
3525 Identification of erythroid cell positive blood transcriptome phenotypes associated with severe respiratory syncytial virus infection
Rinchai, D.; Altman, M. B.; Konza, O.; Hassler, S.; Martina, F.; Toufiq, M.; Garand, M.; Kabeer, B.; Palucka, K.; Mejias, A.; Ramilo, O.; Bedognetti, D.; Mariotti-Ferrandiz, E.; Klatzmann, D.; Chaussabel, D.
10.1101/527812 — immunology — Posted on 2020-05-10
3526 The Setaria viridis genome and diversity panel enables discovery of a novel domestication gene
Mamidi, S.; Healey, A.; Huang, P.; Grimwood, J.; Jenkins, J.; Barry, K.; Sreedasyam, A.; Shu, S.; Lovell, J. T.; Feldman, M.; Wu, J.; Yu, Y.; Chen, C.; Johnson, J.; Sakakibara, H.; Kiba, T.; Sakurai, T.; Tavares, R.; Nusinow, D. A.; Baxter, I.; Schmutz, J.; Brutnell, T.; Kellogg, E. A.
10.1101/744557 — genomics — Posted on 2020-05-10
3527 Dissecting the regulatory activity and sequence content of loci with exceptional numbers of transcription factor associations
Ramaker, R. C.; Hardigan, A. A.; Goh, S.-T.; Partridge, E. C.; Wold, B.; Cooper, S. J.; Myers, R. M.
10.1101/2019.12.21.885830 — genomics — Posted on 2020-05-10
3529 Lack of adaptation to centriolar defects leads to p53-independent microcephaly in the absence of Cep135
Gonzalez-Martinez, J.; Cwersch, A.; Martinez-Alonso, D.; Lopez, L. R.; Almagro, J.; Megias, D.; Boskovic, J.; Gilabert, J.; Grana Castro, O.; Pierani, A.; Behrens, A.; Ortega, S.; Malumbres, M.
10.1101/2020.05.07.082032 — cell biology — Posted on 2020-05-10
3532 Sub-lethal insecticide exposure affects host biting efficiency of Kdr-resistant Anopheles gambiae
Diop, M. M.; Chandre, F.; Rossignol, M.; Porciani, A.; Chateau, M.; Moiroux, N.; Pennetier, C.
10.1101/653980 — animal behavior and cognition — Posted on 2020-05-10
3534 Mutually suppressive roles of KMT2A and KDM5C in behaviour, neuronal structure, and histone H3K4 methylation
Vallianatos, C. N.; Raines, B.; Porter, R. S.; Bonefas, K. M.; Wu, M. C.; Garay, P. M.; Collette, K. M.; Seo, Y. A.; Dou, Y.; Keegan, C. E.; Tronson, N.; Iwase, S.
10.1101/567917 — genetics — Posted on 2020-05-10
3535 Transmission of West Nile and other temperate mosquito-borne viruses peaks at intermediate environmental temperatures
Shocket, M. S.; Verwillow, A. B.; Numazu, M. G.; Slamani, H.; Cohen, J. M.; El Moustaid, F.; Rohr, J. R.; Johnson, L. R.; Mordecai, E. A.
10.1101/597898 — ecology — Posted on 2020-05-10
3536 Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact
Chiasson, M. A.; Rollins, N. J.; Stephany, J. J.; Sitko, K. A.; Matreyek, K. A.; Verby, M.; Sun, S.; Roth, F.; DeSloover, D.; Marks, D. S.; Rettie, A. E.; Fowler, D. M.
10.1101/2020.05.10.087312 — genomics — Posted on 2020-05-10
3537 Interactive MS/MS Visualization with the Metabolomics Spectrum Resolver Web Service
Wang, M.; Rogers, S.; Bittremieux, W.; Chen, C.; Dorrestein, P. C.; Schymanski, E. L.; Schulze, T.; Neumann, S.; Meier, R.
10.1101/2020.05.09.086066 — bioinformatics — Posted on 2020-05-10
3538 Systematic auditing is essential to debiasing machine learning in biology
Eid, F.-E.; Elmarakeby, H.; Chan, Y. A.; Martins, N. F.; Elhefnawi, M.; Van Allen, E.; Heath, L. S.; Lage, K.
10.1101/2020.05.08.085183 — systems biology — Posted on 2020-05-10
3540 Brain Modeling ToolKit: an Open Source Software Suite for Multiscale Modeling of Brain Circuits
Dai, K.; Gratiy, S.; Billeh, Y. N.; Xu, R.; Cai, B.; Cain, N.; Rimehaug, A. E.; Stasik, A. J.; Einevoll, G. T.; Mihalas, S.; Koch, C.; Arkhipov, A.
10.1101/2020.05.08.084947 — neuroscience — Posted on 2020-05-10
3543 Prediction analysis of SARS-COV-2 entry in Livestock and Wild animals
Praharaj, M. R.; Garg, P.; Khan, R. I. N.; Sharma, S.; Panigrahi, M.; Mishra, B. P.; Mishra, B.; kumar, G. S.; Gandham, R. K.; Singh, R. K.; Majumdar, S.; Mohapatra, T.
10.1101/2020.05.08.084327 — microbiology — Posted on 2020-05-10
3547 Structure of the unique tetrameric STENOFOLIA homeodomain bound with DNA
Pathak, P. K.; Zhang, F.; Peng, S.; Niu, L.; Chaturvedi, J.; Tadege, M.; Deng, J.
10.1101/2020.05.08.085126 — biochemistry — Posted on 2020-05-10
3548 Bypass of DNA Interstrand crosslinks by a Rev1-DNA polymerase ζ complex
Buch, R. B.; Cheun, Y. K.; Roy, U.; Schärer, O. D.; Burgers, P. M.
10.1101/2020.05.09.085902 — biochemistry — Posted on 2020-05-10
3550 Diel Oscillations of Particulate Metabolites Reflect Synchronized Microbial Activity in the North Pacific Subtropical Gyre
Boysen, A. K.; Carlson, L. T.; Durham, B. P.; Groussman, R. D.; Aylward, F. O.; Ribalet, F.; Heal, K. R.; DeLong, E. F.; Armbrust, E. V.; Ingalls, A. E.
10.1101/2020.05.09.086173 — ecology — Posted on 2020-05-10
3551 Potential modes of COVID-19 transmission from human eye revealed by single-cell atlas
Hamashima, K.; Gautam, P.; Lau, K. A.; Khiong, C. W.; Blenkinsop, T. A.; Li, H.; Loh, Y. H.
10.1101/2020.05.09.085613 — genomics — Posted on 2020-05-10
3554 Isolation of full-length IgG antibodies from combinatorial libraries expressed in the cytoplasm of Escherichia coli
Robinson, M.-P.; Cox, E. C.; Li, M.; Jaroentomeechai, T.; Zheng, X.; Chang, M.; Berkmen, M.; DeLisa, M. P.
10.1101/2020.05.09.085944 — synthetic biology — Posted on 2020-05-10
3558 Reassembly of soil fungal communities under reforestation and herbivore exclusion
Tatsumi, S.; Matsuoka, S.; Fujii, S.; Makoto, K.; Osono, T.; Isbell, F.; Mori, A. S.
10.1101/2020.05.09.086025 — ecology — Posted on 2020-05-10
3559 Clinical Knowledge Graph Integrates Proteomics Data into Clinical Decision-Making
Santos, A.; Colaco, A. R.; Nielsen, A. B.; Niu, L.; Geyer, P. E.; Coscia, F.; Wewer Albrechtsen, N. J.; Mundt, F.; Jensen, L. J.; Mann, M.
10.1101/2020.05.09.084897 — bioinformatics — Posted on 2020-05-10
3562 A Comparison of Pruning During Multi-Step Planning in Depressed and Healthy Individuals
Faulkner, P.; Huys, Q.; Renz, D.; Eshel, N.; Pilling, S.; Dayan, P.; Roiser, J.
10.1101/2020.05.08.084509 — systems biology — Posted on 2020-05-10
3565 Somatostatin receptor subtypes 1 and 4 redundantly regulate neprilysin, the major amyloid beta-degrading enzyme, in brain
Nilsson, P.; Sorgjerd, K.; Kakiya, N.; Sasaguri, H.; Shimozawa, M.; Tsubuki, S.; Takamura, R.; Zhou, Z.; Loera-Valencia, R.; Sekiguchi, M.; Petrish, A.; Schulz, S.; Saito, T.; Winblad, B.; Saido, T.
10.1101/2020.05.09.085795 — neuroscience — Posted on 2020-05-10
3569 Developmentally Delayed Epigenetic Reprogramming Underlying the Pathogenesis of Preeclampsia
He, W.; Wei, Y.; Gong, X.; Chang, L.; Jin, W.; Liu, K.; Wang, X.; Xiao, Y.; Zhang, W.; Chen, Q.; Wu, K.; Liang, L.; Liu, J.; Chen, Y.; Guo, H.; Li, X.; Chen, W.; Yang, J.; Qi, Y.; Zhang, Y.; Yin, A.
10.1101/2020.05.08.085290 — genomics — Posted on 2020-05-10
3571 Single cell RNA sequencing reveals the landscape of early female germ cell development
Zhao, Z.-H.; Ma, J.-Y.; Meng, T.-G.; Wang, Z.-B.; Yue, W.; Zhou, Q.; Li, S.; Feng, X.; Hou, Y.; Schatten, H.; Ou, X.-H.; Sun, Q.-Y.
10.1101/2020.05.09.085845 — developmental biology — Posted on 2020-05-10
3574 SpaGE: Spatial Gene Enhancement using scRNA-seq
Abdelaal, T.; Mourragui, S.; Mahfouz, A.; Reinders, M.
10.1101/2020.05.08.084392 — bioinformatics — Posted on 2020-05-10
3576 Mitochondrial fatty acid synthesis coordinates mitochondrial oxidative metabolism
Nowinski, S. M.; Solmonson, A.; Rusin, S. F.; Maschek, J. A.; Bensard, C. L.; Fogarty, S.; Jeong, M.-Y.; Lettlova, S.; Berg, J. A.; Morgan, J. T.; Ouyang, Y.; Naylor, B. C.; Paulo, J. A.; Funai, K.; Cox, J.; Gygi, S. P.; Winge, D. R.; DeBerardinis, R.; Rutter, J.
10.1101/2020.05.09.086199 — biochemistry — Posted on 2020-05-10
3581 The Genetic Architecture of DNA Replication Timing in Human Pluripotent Stem Cells
Ding, Q.; Edwards, M. M.; Hulke, M. L.; Bracci, A. N.; Hu, Y.; Tong, Y.; Zhu, X.; Hsiao, J.; Charvet, C. J.; Ghosh, S.; Handsaker, R. E.; Eggan, K.; Merkle, F. T.; Gerhardt, J.; Egli, D.; Clark, A. G.; Koren, A.
10.1101/2020.05.08.085324 — genomics — Posted on 2020-05-10
3583 Multiscale Characterization of Complex Binding Interactions of Cellulolytic Enzymes Highlights Limitations of Classical Approaches
Chundawat, S. P. S.; Nemmaru, B.; Hackl, M.; Brady, S. K.; Hilton, M. A.; Johnson, M. M.; Chang, S.; Lang, M. J.; Huh, H.; Lee, S.-H.; Yarbrough, J. M.; Lopez, C. A.; Gnanakaran, S.
10.1101/2020.05.08.084152 — biochemistry — Posted on 2020-05-10
3584 Functional requirement of the Arabidopsis importin-α nuclear transport receptor family in autoimmunity mediated by the NLR protein SNC1
Lüdke, D.; Roth, C.; Kamrad, S. A.; Messerschmidt, J.; Hartken, D.; Appel, J.; Hörnich, B. F.; Yan, Q.; Kusch, S.; Klenke, M.; Gunkel, A.; Wirthmueller, L.; Wiermer, M.
10.1101/2020.05.09.084020 — plant biology — Posted on 2020-05-10
3585 Born to be young: prenatal thyroid hormones increase early-life telomere length
Stier, A.; Hsu, B.-Y.; Marciau, C.; Doligez, B.; Gustafsson, L.; Bize, P.; Ruuskanen, S.
10.1101/2020.05.07.083667 — physiology — Posted on 2020-05-10
3588 Time-dependent roles of adolescent- and adult-born dentate granule neurons in spatial learning
Masachs, N.; Charrier, V.; Farrugia, F.; Lemaire, V.; Mazier, W.; Blin, N.; Tronel, S.; Montaron, M.-F.; Ge, S.; Cota, D.; Deroche-Gamonet, V.; Herry, C.; Abrous, N.
10.1101/2020.05.08.084467 — neuroscience — Posted on 2020-05-10
3590 Genome-wide association study of school grades identifies a genetic overlap between language ability, psychopathology and creativity
Rajagopal, V. M.; Ganna, A.; Coleman, J. R.; Allegrini, A. G.; Voloudakis, G.; Grove, J.; Als, T. D.; Horsdal, H. T.; Petersen, L. V.; Appadurai, V.; Schork, A.; Buil, A.; Bulik, C.; Bybjerg-Grauholm, J.; Baekvad-Hansen, M.; Hougaard, D. M.; Mors, O.; Nordentoft, M.; Werge, T.; iPSYCH-Broad Consortium, ; Mortensen, P. B.; Breen, G.; Plomin, R.; Agerbo, E.; Borglum, A.; Demontis, D.
10.1101/2020.05.09.075226 — genomics — Posted on 2020-05-10
3592 Identification and genetic diversity analysis of a male-sterile gene (MS1) in Japanese cedar (Cryptomeria japonica D. Don)
Hasegawa, Y.; Ueno, S.; Wei, F.-J.; Matsumoto, A.; Uchiyama, K.; Ujino-Ihara, T.; Hakamata, T.; Fujino, T.; Kasahara, M.; Bino, T.; Yamaguchi, K.; Shigenobu, S.; Tsumura, Y.; Moriguchi, Y.
10.1101/2020.05.09.085464 — genetics — Posted on 2020-05-10
3593 Multiple origins of insular woodiness on the Canary Islands are consistent with palaeoclimatic aridification
Hooft van Huysduynen, A.; Janssens, S.; Merckx, V.; Vos, R.; Valente, L.; Zizka, A.; Larter, M.; Karabayir, B.; Maaskant, D.; Witmer, Y.; Fernandez-Palacios, J. M.; de Nascimento, L.; Jaen Molina, R.; Marrero-Rodriguez, A.; del Arco, M.; Lens, F.
10.1101/2020.05.09.084582 — evolutionary biology — Posted on 2020-05-10
3595 Hypoxia driven oncometabolite L-2HG maintains "stemness"-differentiation balance and facilitates immune suppression in pancreatic cancer
Gupta, V. K.; Durden, B.; Garrido, V. T.; Sharma, N. S.; Kesh, K.; Edwards, D.; Myers, C.; Bhattacharya, S. K.; Saluja, A.; Singh, P. K.; Banerjee, S.
10.1101/2020.05.08.084244 — cancer biology — Posted on 2020-05-10
3596 Developmental chromatin programs determine oncogenic competence in melanoma
Baggiolini, A.; Callahan, S. J.; Trieu, T.; Tagore, M. M.; Montal, E.; Weiss, J. M.; Tischfield, S. E.; Fan, Y.; Campbell, N. R.; Saurat, N.; Hollmann, T.; Simon-Vermot, T.; Tickoo, S. K.; Taylor, B. S.; Koche, R.; Khurana, E.; Studer, L.; White, R. M.
10.1101/2020.05.09.081554 — cancer biology — Posted on 2020-05-10
3599 Mechanical Tension in Syndecan-1 is Regulated by Extracellular Mechanical Cues and Fluidic Shear Stress
Le, V.; Mei, L.; Voyvodic, P. L.; Zhao, C.; Busch, D. J.; Stachowiak, J. C.; Baker, A. B.
10.1101/2020.05.09.085894 — bioengineering — Posted on 2020-05-10
3603 Converting endogenous genes of the malaria mosquito into simple non-autonomous gene drives for population replacement
Hoermann, A.; Tapanelli, S.; Capriotti, P.; Masters, E. K.; Habtewold, T.; Christophides, G. K.; Windbichler, N.
10.1101/2020.05.09.086157 — synthetic biology — Posted on 2020-05-10
3606 The Suprachiasmatic Nucleus Regulates Anxiety-Like Behavior in Mice
Vadnie, C. A.; Eberhardt, L. A.; Hildebrand, M. A.; Zhang, H.; Becker-Krail, D.; DePoy, L. M.; Logan, R. W.; McClung, C. A.
10.1101/2020.05.08.085217 — neuroscience — Posted on 2020-05-10
3608 Generating Artificial Sensations with Spinal Cord Stimulation in Primates and Rodents
Yadav, A. P.; Li, S.; Krucoff, M. O.; Lebedev, M. A.; Abd-El-Barr, M. M.; Nicolelis, M. A. L.
10.1101/2020.05.09.085647 — neuroscience — Posted on 2020-05-10
3611 Pulmonary infection interrupts acute cutaneous wound healing through disruption of chemokine signals
Crane, M. J.; Xu, Y.; Monaghan, S. F.; Hall, B. M.; Albina, J. E.; Henry, W. L.; Tran, H. L.; Chhabria, K. R. P.; Jordon, A. R. D.; Carlsen, L.; Jamieson, A. M.
10.1101/2020.05.08.084442 — immunology — Posted on 2020-05-10
3613 The rise of the three-spined stickleback: eco-evolutionary consequences of a mesopredator release
Eriksson, B. K.; Yanos, C.; Bourlat, S.; Donadi, S.; Fontaine, M.; Hansen, J.; Jakubaviciute, E.; Kiragosyan, K.; Maan, M.; Merila, J.; Austin, A.; Olsson, J.; Reiss, K.; Sundblad, G.; Bergstrom, U.; Eklof, J.
10.1101/2020.05.08.083873 — ecology — Posted on 2020-05-10
3614 Impacts of the Samarco tailing dam collapse on metals and arsenic concentration in freshwater fish muscle from Doce River, southeastern Brazil
Ferreira, F. F.; Freitas, M. B.; Szinwelski, N.; Vicente, N.; Medeiros, L. C. C.; Schaefer, C. E. G. R.; Dergam, J. A.; SPERBER, C. F.
10.1101/2020.05.09.086058 — ecology — Posted on 2020-05-10
3615 Novel antiproliferative tripeptides block AP-1 transcriptional complex by in silico approach
Kumar, A.; Kothari, J.; Sinchana, S. T.; Lokhande, K.; Swamy, K. V.; Sharma, N. K.
10.1101/2020.05.08.083972 — cancer biology — Posted on 2020-05-10
3616 MSCs Successfully Deliver Oncolytic Virotherapy to Diffuse Intrinsic Pontine Glioma
Chastkofsky, M.; Pituch, K. C.; Katagi, H.; Ilut, L.; Xiao, T.; Han, Y.; Sonabend, A. M.; Curiel, D. T.; Bonner, E. R.; Nazarian, J.; Horbinski, C.; James, C. D.; Saratsis, A.; Hashizume, R.; Lesniak, M. S.; Balyasnikova, I. V.
10.1101/2020.05.09.085837 — cancer biology — Posted on 2020-05-10
3617 Extending the Martini coarse-grained forcefield to N-glycans
Shivgan, A. T.; Marzinek, J. K.; Huber, R. G.; Krah, A.; Henchman, R. H.; Matsudaira, P.; Verma, C. S.; Bond, P. J.
10.1101/2020.05.08.085399 — biophysics — Posted on 2020-05-10
3619 Mapping glycan-mediated galectin-3 interactions by live cell proximity labeling
Joeh, E.; O'Leary, T.; Li, W.; Hawkins, R.; Hung, J.; Parker, C. G.; Huang, M. L.
10.1101/2020.05.09.058586 — biochemistry — Posted on 2020-05-10
3627 Genomic analysis of worldwide sheep breeds reveals PDGFD a major target of fat-tail selection in sheep
Dong, K.; Yang, M.; Han, J.; Han, J.; Song, Z.; Ma, Q.; Luosang, C.; Gorkhali, N. A.; Yang, B.; He, X.; Ma, Y.; Jiang, L.
10.1101/2020.05.08.085431 — genomics — Posted on 2020-05-10
3628 Local genetic correlation analysis reveals heterogeneous etiologic sharing of complex traits
Zhang, Y.; Lu, Q.; Ye, Y.; Huang, K.; Liu, W.; Wu, Y.; Zhong, X.; Li, B.; Yu, Z.; Travers, B.; Werling, D.; Li, J. J.; Zhao, H.
10.1101/2020.05.08.084475 — genetics — Posted on 2020-05-10
3629 White pupae genes in the Tephritids Ceratitis capitata, Bactrocera dorsalis and Zeugodacus cucurbitae: a story of parallel mutations
Ward, C. M.; Aumann, R. A.; Whitehead, M. A.; Nikolouli, K.; Leveque, G.; Gouvi, G.; Fung, E.; Reiling, S. J.; Djambazian, H. H. V.; Hughes, M. A.; Whiteford, S.; Caceres-Barrios, C.; Nguyen, N. M. T.; Choo, A.; Crisp, P.; Sim, S.; Geib, S.; Marec, F.; Haecker, I.; Ragoussis, I.; Darby, A. C.; Bourtzis, K.; Baxter, S. W.; Schetelig, M. F.
10.1101/2020.05.08.076158 — genetics — Posted on 2020-05-10
3631 Functionally unique, specialised, and endangered (FUSE) species: towards integrated metrics for the conservation prioritisation toolbox
Griffin, J. N.; Leprieur, F.; Silvestro, D.; Lefcheck, J. S.; Albouy, C.; Rasher, D. B.; Davis, M.; Svenning, J.-C.; Pimiento, C.
10.1101/2020.05.09.084871 — ecology — Posted on 2020-05-10
3633 Rapid Assembly and Screening of Multivalent Immune Cell-Redirecting Therapies for Leukemia
Do, P.; Perdue, L. A.; Chyong, A.; Hunter, R.; Dougan, J.; Henry, C. J.; Porter, C. C.; Dreaden, E. C.
10.1101/2020.05.08.082628 — bioengineering — Posted on 2020-05-10
3637 E2F4 as a single multifactorial target against Alzheimer's disease
Lopez-Sanchez, N.; Ramon-Landreau, M.; Trujillo, C.; Garrido-Garcia, A.; Frade, J. M.
10.1101/2020.05.08.082784 — pathology — Posted on 2020-05-10
3638 Differential functional neural circuitry behind autism subtypes with marked imbalance between social-communicative and restricted repetitive behavior symptom domains
Bertelsen, N.; Landi, I.; Bethlehem, R. A. I.; Seidlitz, J.; Busuoli, E. M.; Mandelli, V.; Satta, E.; Trakoshis, S.; Auyeung, B.; Kundu, P.; Loth, E.; Dumas, G.; Baumeister, S.; Beckmann, C. F.; Bolte, S.; Bourgeron, T.; Charman, T.; Durston, S.; Ecker, C.; Holt, R.; Johnson, M. H.; Jones, E. J. H.; Mason, L.; Meyer-Lindenberg, A.; Moessnang, C.; Oldehinkel, M.; Persico, A.; Tillmann, J.; Williams, S. C. R.; Spooren, W.; Murphy, D. G. M.; Buitelaar, J. K.; EU-AIMS LEAP group, ; Baron-Cohen, S.; Lai, M.-C.; Lombardo, M. V.
10.1101/2020.05.08.083758 — neuroscience — Posted on 2020-05-10
3640 Primate-specific response of astrocytes to stroke limits peripheral macrophage infiltration
Boghdadi, A. G.; Spurrier, J.; Teo, L.; Li, M.; Skarica, M.; Cao, B.; Kwan, W.; Merson, T. D.; Nilsson, S. K.; Sestan, N.; Strittmatter, S. M.; Bourne, J. A.
10.1101/2020.05.08.083501 — neuroscience — Posted on 2020-05-10
3641 History of childbirths relates to region-specific brain aging patterns in middle and older-aged women
de Lange, A.-M. G.; Barth, C.; Kaufmann, T. G.; Anatürk, M.; Suri, S.; Ebmeier, K. P.; Westlye, L. T.
10.1101/2020.05.08.084616 — neuroscience — Posted on 2020-05-10
3642 Connectome and microcircuit models implicate atypical subcortico-cortical interactions in autism pathophysiology
Park, B.-y.; Hong, S.-J.; Valk, S. L.; Paquola, C.; Benkarim, O.; Bethlehem, R. A. I.; Di Martino, A.; Milham, M.; Gozzi, A.; Yeo, B. T. T.; Smallwood, J.; Bernhardt, B.
10.1101/2020.05.08.077289 — neuroscience — Posted on 2020-05-10
3646 An evolutionarily conserved metallophosphodiesterase is a determinant of lifespan in Drosophila
Gupta, K.; Janardan, V.; Banerjee, S.; Chakrabarti, S.; Srinivas, S.; Mahishi-Vasuki, D.; PADINJAT, R.; Visweswariah, S. S.
10.1101/2020.05.08.084137 — developmental biology — Posted on 2020-05-10
3647 Furry is required for cell movements during gastrulation and functionally interacts with NDR1
Cervino, A. S.; Moretti, B.; Stuckenholz, C.; Grecco, H. E.; Davidson, L. A.; Cirio, M. C.
10.1101/2020.05.08.083980 — developmental biology — Posted on 2020-05-10
3654 Ray tracing models for estimating light collection properties of microstructured tapered optical fibers for optical neural interfaces
Maglie, E.; Pisanello, M.; Pisano, F.; Balena, A.; Bianco, M.; Spagnolo, B.; Sileo, L.; Sabatini, B. L.; De Vittorio, M.; Pisanello, F.
10.1101/2020.05.07.083469 — bioengineering — Posted on 2020-05-10
3659 Joint probabilistic modeling of paired transcriptome and proteome measurements in single cells
Gayoso, A.; Steier, Z.; Lopez, R.; Regier, J.; Nazor, K. L.; Streets, A.; Yosef, N.
10.1101/2020.05.08.083337 — bioinformatics — Posted on 2020-05-10
3663 L-bodies are novel RNA-protein condensates driving RNA transport in Xenopus oocytes
Neil, C. R.; Jeschonek, S. P.; Cabral, S. E.; O'Connell, L. C.; Powrie, E. A.; Wood, T. A.; Mowry, K. L.
10.1101/2020.05.08.084814 — cell biology — Posted on 2020-05-10
3665 Irisin directly stimulates osteoclastogenesis and bone resorption in vitro and in vivo
Estell, E. G.; Le, P. T.; Vegting, Y.; Kim, H.; Baron, R.; Spiegelman, B.; Rosen, C. J.
10.1101/2020.05.09.085977 — cell biology — Posted on 2020-05-10
3667 Disrupted Endothelial Cell Heterogeneity and Network Organization Impairs Vascular Function in Prediabetic Obesity
Wilson, C.; Zhang, X.; Lee, M. D.; MacDonald, M.; Heathcote, H.; Alorfi, N.; Buckley, C.; Dolan, S.; McCarron, J. G.
10.1101/2020.05.07.083543 — cell biology — Posted on 2020-05-10
3668 Labeling subcellular structures in living specimens using live-cell incompatible dyes with excellent optical properties
Han, Y.; Zhang, Z.; Liu, W.; Yao, Y.; Chen, Y.; Luo, X.; Wang, W.; Xu, Y.; Liu, X.; Kuang, C.; Hao, X.
10.1101/2020.05.10.086538 — cell biology — Posted on 2020-05-10
3672 Condensation of pericentrin proteins in human cells illuminates phase separation in centrosome assembly
Jiang, X.; Ho, D. B. T.; Mahe, K.; Mia, J.; Sepulveda, G.; Antkowiak, M.; Yamada, S.; Jao, L.-E.
10.1101/2020.05.08.084749 — cell biology — Posted on 2020-05-10
3674 Antiviral signalling in human IPSC-derived neuronsrecapitulates neurodevelopmental disorder phenotypes
Warre Cornish, K.; Perfect, L.; Nagy, R.; Reid, M. J.; Mueller, A.; Evans, A.; Ghevaert, C.; McAlonan, G.; Loth, E.; Murphy, D.; Srivastava, D. P.; Price, J.
10.1101/789321 — neuroscience — Posted on 2020-05-10
3680 Plasmodium falciparum-specific IgM B cells dominate in children, expand with malaria and produce parasite inhibitory IgM
Hopp, C.; Diouf, A.; Miura, K.; Boswell, K.; Sekar, P.; Skinner, J.; Tipton, C. M.; Chambers, M.; Andrews, S.; Tan, J.; Li, S.; Doumbo, S.; Kayentao, K.; Ongoiba, A.; Traore, B.; Portugal, S.; Long, C.; Koup, R. A.; Long, E. O.; McDermott, A. B.; Crompton, P. D.
10.1101/2020.04.12.030049 — immunology — Posted on 2020-05-10
3681 Regulatory T cell expansion by a highly CD25-dependent IL-2 mutein arrests ongoing autoimmunity
Khoryati, L.; Pham, M. N.; Sherve, M.; Kumari, S.; Cook, K.; Pearson, J.; Bogdani, M.; Campbell, D. J.; Gavin, M. A.
10.1101/862789 — immunology — Posted on 2020-05-10
3686 The CCCTC-binding factor CTCF represses hepatitis B virus Enhancer I and regulates viral transcription
D'Arienzo, V.; Ferguson, J.; Giraud, G.; Chapus, F.; Harris, J. M.; Wing, P. A.; Claydon, A.; Begum, S.; Zhuang, X.; Balfe, P.; Testoni, B.; McKeating, J. A.; Parish, J. L.
10.1101/2020.05.08.085548 — microbiology — Posted on 2020-05-09
3687 A universal subcuticular bacterial symbiont of a coral predator, the crown-of-thorns starfish, in the Indo-Pacific
Wada, N.; Yuasa, H.; Kajitani, R.; Gotoh, Y.; Ogura, Y.; Yoshimura, D.; Toyoda, A.; Tang, S.-L.; Higashimura, Y.; Sweatman, H.; Forsman, Z. H.; Bronstein, O.; Eyal, G.; Thongtham, N.; Itoh, T.; Hayashi, T.; Yasuda, N.
10.1101/2020.02.13.947093 — microbiology — Posted on 2020-05-09
3689 Describing the current status of Plasmodium falciparum population structure and drug resistance within mainland Tanzania using molecular inversion probes
Moser, K. A.; Madebe, R. A.; Aydemir, O.; Chiduo, M. G.; Mandara, C. I.; Rumisha, S. F.; Chaky, F.; Denton, M.; Marsh, P. W.; Verity, R.; Watson, O. J.; Ngasala, B.; Mkude, S.; Molteni, F.; Njau, R.; Warsame, M.; Mandike, R.; Kabanywanyi, A. M.; Mahende, M. K.; Kamugisha, E.; Ahmed, M.; Kavishe, R. A.; Greer, G.; Kitojo, C. A.; Reaves, E. J.; Mlunde, L.; Bishanga, D.; Mohamed, A.; Juliano, J. J.; Ishengoma, D. S.; Bailey, J. A.
10.1101/2020.05.09.085225 — genomics — Posted on 2020-05-09
3690 Demonstration of Patient-Specific Simulations To Assess Left Atrial Appendage Thrombogenesis Risk
Garcia-Villalba, M.; Rossini, L.; Gonzalo, A.; Vigneault, D.; Martinez-Legazpi, P.; Flores, O.; Bermejo, J.; McVeigh, E.; Kahn, A. M.; del Alamo, J. C.
10.1101/2020.05.07.083220 — bioengineering — Posted on 2020-05-09
3691 Light pollution affects West Nile virus exposure risk across Florida.
Kernbach, M. E.; Martin, L. B.; Unnasch, T. R.; Hall, R. J.; Jiang, R. H.; Francis, C. D.
10.1101/2020.05.08.082974 — ecology — Posted on 2020-05-09
3696 Characterization, modelling and mitigation of gene expression burden in mammalian cells
Frei, T.; Cella, F.; Tedeschi, F.; Gutierrez, J.; Stan, G.-B.; Khammash, M.; Siciliano, V.
10.1101/867549 — synthetic biology — Posted on 2020-05-09
3698 The microbiome mediates subchondral bone loss and metabolomic changes after acute joint trauma
Hahn, A. K.; Wallace, C. W.; Welhaven, H. D.; Brooks, E.; McAlpione, M.; Christiansen, B. A.; Walk, S. T.; June, R. K.
10.1101/2020.05.08.084822 — immunology — Posted on 2020-05-09
3699 A Genetic Model Therapy Proposes a Critical Role for Liver Dysfunction in Mitochondrial Biology and Disease
Sabharwal, A.; Wishman, M. D.; Cervera, R. L.; Serres, M. R.; Anderson, J. L.; Treichel, A. J.; Ichino, N.; Liu, W.; Yang, J.; Ding, Y.; Deng, Y.; Farber, S. A.; Clark, K. J.; Xu, X.; Ekker, S. C.
10.1101/2020.05.08.084681 — genetics — Posted on 2020-05-09
3708 Central role and structure of the membrane pseudokinase YukC in the antibacterial Bacillus subtilis Type VIIb Secretion System.
Tassinari, M.; Doan, T.; Bellinzoni, M.; Chabalier, M.; Ben-Assaya, M.; Martinez, M.; Gaday, Q.; Alzari, P. M.; Cascales, E.; Fronzes, R.; GUBELLINI, F.
10.1101/2020.05.09.085852 — microbiology — Posted on 2020-05-09
3710 Airway Gene-Expression Classifiers for Respiratory Syncytial Virus (RSV) Disease Severity in Infants
Wang, L.; Chu, C.-Y.; McCall, M. N.; Slaunwhite, C.; Holden-Wiltse, J.; Corbett, A.; Falsey, A. R.; Topham, D. J.; Caserta, M. T.; Mariani, T. J.; Walsh, E. E.; Qiu, X.
10.1101/628701 — immunology — Posted on 2020-05-09
3711 No Difference in 2D:4D Ratio between Youth with Elevated Prenatal Androgen Exposure due to Congenital Adrenal Hyperplasia and Controls
Nave, G.; Koppin, C. M.; Manfredi, D.; Richards, G.; Watson, S. J.; Geffner, M. E.; Yong, J. E.; Kim, R.; Ross, H. M.; Serrano-Gonzalez, M.; Kim, M. S.
10.1101/2020.05.07.082529 — developmental biology — Posted on 2020-05-09
3712 Identification of Functional Noncoding RNA-encoded Proteins on Lipid Droplets
Huang, T.; Bamigbade, A. T.; Xu, S.; Deng, Y.; Xie, K.; Ogunsade, O. O.; Mirza, A. H.; Wang, J.; Liu, P.; Zhang, S.
10.1101/2020.04.10.036160 — cell biology — Posted on 2020-05-09
3713 Robust and Gradient Thickness Porous Membranes for In Vitro Modeling of Physiological Barriers
Gholizadeh, S.; Allahyari, Z.; Carter, R.; Delgadillo, L.; Blaquiere, M.; Nouguier-Morin, F.; Marchi, N.; Gaborski, T. R.
10.1101/2020.05.07.083188 — bioengineering — Posted on 2020-05-09
3719 Metabolomic and Proteomic Stratification of Equine Osteoarthritis
Anderson, J. R.; Phelan, M. M.; Caamano-Gutierrez, E.; Clegg, P. D.; Rubio-Martinez, L. M.; Peffers, M. J.
10.1101/2020.05.04.077305 — molecular biology — Posted on 2020-05-09
3721 Pre-treatment of the clinical sample with Proteinase K allows detection of SARS-CoV-2 in the absence of RNA extraction
Mallmann, L.; Schallenberger, K.; Demoliner, M.; Antunes Eisen, A. K.; Hermann, B. S.; Heldt, F. H.; Hansen, A. W.; Spilki, F. R.; Fleck, J. D.
10.1101/2020.05.07.083139 — microbiology — Posted on 2020-05-09
3723 Reverse regression increases power for detecting trans-eQTLs
Banerjee, S.; Simonetti, F. L.; Detrois, K. E.; Kaphle, A.; Mitra, R.; Nagial, R.; Soeding, J.
10.1101/2020.05.07.083386 — genetics — Posted on 2020-05-09
3725 Computational analysis of ligand dose range thermal proteome profiles
Kurzawa, N.; Becher, I.; Sridharan, S.; Franken, H.; Mateus, A.; Anders, S.; Bantscheff, M.; Huber, W.; Savitski, M. M.
10.1101/2020.05.08.083709 — bioinformatics — Posted on 2020-05-09
3726 CytofRUV: Removing unwanted variation to integrate multiple CyTOF datasets
Trussart, M.; Teh, C. E.; Tan, T.; Leong, L.; Gray, D. H.; Speed, T. P.
10.1101/2020.05.09.085621 — bioinformatics — Posted on 2020-05-09
3728 Single cell fitness landscapes induced by genetic and pharmacologic perturbations in cancer
Salehi, S.; Kabeer, F.; Ceglia, N.; Andronescu, M.; Williams, M.; Campbell, K. R.; Masud, T.; Wang, B.; Biele, J.; Brimhall, J.; Ting, J.; Zhang, A. W.; OFlanagan, C. H.; Dorri, F.; Rusk, N.; Lee, H.; Algara, T.; Lee, S. R.; Cheng, B. Y. C.; Eirew, P.; Kono, T.; Pham, J.; Grewal, D.; Lai, D.; Moore, R. A.; Mungall, A. J.; Marra, M.; Consortium, I.; McPherson, A.; Bouchard-Cote, A.; Aparicio, S.; Shah, S. P.
10.1101/2020.05.08.081349 — cancer biology — Posted on 2020-05-09
3732 Proteomic Analysis Uncovers Measles Virus Protein C Interaction with p65/iASPP/p53 Protein Complex
Meignie, A.; Combredet, C.; Santolini, M.; Kovacs, I. A.; Douche, T.; Giai Gianetto, Q.; Eun, H.; Matondo, M.; Jacob, Y.; Grailhe, R.; Tangy, F.; Komarova, A. V.
10.1101/2020.05.08.084418 — microbiology — Posted on 2020-05-09
3733 Zika virus infection during pregnancy protects against secondary infection in the absence of CD8+ cells
Schouest, B.; Gilbert, M. H.; Bohm, R. P.; Schiro, F.; Aye, P. P.; Panganiban, A. T.; Magnani, D. M.; Maness, N. J.
10.1101/2020.05.08.082610 — immunology — Posted on 2020-05-09
3736 Genetic architecture of a body color cline in Drosophila americana
Sramkoski, L. L.; McLaughlin, W. N.; Cooley, A. M.; Yuan, D. C.; John, A.; Wittkopp, P.
10.1101/2020.05.07.074211 — evolutionary biology — Posted on 2020-05-09
3740 A phylodynamic workflow to rapidly gain insights into the dispersal history and dynamics of SARS-CoV-2 lineages
Dellicour, S.; Durkin, K.; Hong, S. L.; Vanmechelen, B.; Marti-Carreras, J.; Gill, M. S.; Meex, C.; Bontems, S.; Andre, E.; Gilbert, M.; Walker, C.; De Maio, N.; Hadfield, J.; Hayette, M.-P.; Bours, V.; Wawina-Bokalanga, T.; Artesi, M.; Baele, G.; Maes, P.
10.1101/2020.05.05.078758 — evolutionary biology — Posted on 2020-05-09
3744 Acid sphingomyelinase inhibition results in profound rescue of neuronal function in glucocerebrosidase deficiency
Keatinge, M.; Gegg, M.; Watson, L.; Mortiboys, H.; Li, N.; Dunning, M. J.; Ailani, D.; Bui, H.; van Leens, A.; Lefeber, D.; MacDonald, R.; Schapira, A.; Bandmann, O.
10.1101/702340 — neuroscience — Posted on 2020-05-09
3745 Flanker task-elicited Event Related Potential sources reflect human recombinant Erythropoietin differential effects on Parkinson patients
Bringas Vega, M. L.; Liu, S.; Zhang, M.; Pedroso Ibanez, I.; Morales Chacon, L. M.; Galan Garcia, L.; Perez Bocourt, V.; Jahanshahi, M.; Valdes-Sosa, P. A.
10.1101/864397 — neuroscience — Posted on 2020-05-09
3746 Identification of neutralizing human monoclonal antibodies from Italian Covid-19 convalescent patients
Andreano, E.; Nicastri, E.; Paciello, I.; Pileri, P.; Manganaro, N.; Piccini, G.; Manenti, A.; Troisi, M.; Vacca, F.; Pantano, E.; De Santi, C.; Cardamone, D.; Kabanova, A.; Agrati, C.; Castilletti, C.; Capobianchi, M. R.; Emiliozzi, A.; Fabbiani, M.; Montagnani, F.; Montomoli, E.; Sala, C.; Ippolito, G.; Rappuoli, R.
10.1101/2020.05.05.078154 — immunology — Posted on 2020-05-09
3748 Confound modelling in UK Biobank brain imaging
Alfaro-Almagro, F.; McCarthy, P.; Afyouni, S.; Andersson, J. L. R.; Bastiani, M.; Miller, K. L.; Nichols, T.; Smith, S. M.
10.1101/2020.03.11.987693 — neuroscience — Posted on 2020-05-09
3749 Gray whale transcriptome reveals longevity adaptations associated with DNA repair and ubiquitination
Toren, D.; Kulaga, A.; Jethva, M.; Rubin, E.; Snezhkina, A.; Kudryavtseva, A.; Nowicki, D.; Tacutu, R.; Moskalev, A.; Fraifeld, V.
10.1101/754218 — evolutionary biology — Posted on 2020-05-09
3750 The vulnerability of working memory to distraction is rhythmic
Woestmann, M.; Lui, T. K.-Y.; Friese, K.-H.; Kreitewolf, J.; Naujokat, M.; Obleser, J.
10.1101/2020.02.26.965848 — neuroscience — Posted on 2020-05-09
3752 Macromolecular and electrical coupling between inner hair cells in the rodent cochlea
Jean, P.; Anttonen, T.; Michanski, S.; Garcia de Diego, A. M.; Steyer, A. M.; Neef, A.; Oestreicher, D.; Kroll, J.; Nardis, C.; Pangrsic, T.; Moebius, W.; Ashmore, J.; Wichmann, C.; Moser, T.
10.1101/2019.12.17.879767 — neuroscience — Posted on 2020-05-09
3754 Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19
Dong, C.; Nakagawa, R.; Oyama, K.; Yamamoto, Y.; Zhang, W.; Li, Y.; Yoshimura, Y.; Kamiya, H.; Nakayama, J.-i.; Ueda, J.; Min, J.
10.1101/2020.05.08.085233 — molecular biology — Posted on 2020-05-09
3755 Tunable hetero-assembly of a plant pseudoenzyme-enzyme complex
Novikova, I. V.; Zhou, M.; Du, C.; Parra, M.; Kim, D. N.; VanAernum, Z. L.; Shaw, J. B.; Hellmann, H.; Wysocki, V. H.; Evans, J. E.
10.1101/717082 — molecular biology — Posted on 2020-05-09
3756 Photorespiration pathways in a chemolithoautotroph
Claassens, N. J.; Scarinci, G.; Fischer, A.; Flamholz, A. I.; Newell, W.; Frielingsdorf, S.; Lenz, O.; Bar-Even, A.
10.1101/2020.05.08.083683 — microbiology — Posted on 2020-05-09
3757 Long-term homeostatic T cell proliferation is driven by AMPK-dependent regulation of oxygen reactive species
Lepez, A.; Pirnay, T.; Denanglaire, S.; Perez-Morga, D.; Vermeersch, M.; Leo, O.; Andris, F.
10.1101/2020.03.06.978791 — immunology — Posted on 2020-05-09
3758 A Genetic Model Therapy Proposes a Critical Role for Liver Dysfunction in Mitochondrial Biology and Disease
Sabharwal, A.; Wishman, M. D.; Cervera, R. L.; Serres, M. R.; Anderson, J. L.; Treichel, A. J.; Ichino, N.; Liu, W.; Yang, J.; Ding, Y.; Deng, Y.; Farber, S. A.; Clark, K. J.; Xu, X.; Ekker, S. C.
10.1101/2020.05.08.084681 — genetics — Posted on 2020-05-09
3759 How spiders make their eyes: Systemic paralogy and function of retinal determination network homologs in arachnids
Gainett, G.; Ballesteros, J. A.; Kanzler, C. R.; Zehms, J. T.; Zern, J. M.; Aharon, S.; Gavish-Regev, E.; Sharma, P. P.
10.1101/2020.04.28.067199 — developmental biology — Posted on 2020-05-09
3760 Structural basis for active-site probes targeting Staphylococcus aureus serine hydrolase virulence factors
Fellner, M.; Lentz, C. S.; Jamieson, S. A.; Brewster, J. L.; Chen, L.; Bogyo, M.; Mace, P. D.
10.1101/2020.04.21.054437 — biochemistry — Posted on 2020-05-09
3761 Spontaneous polyploids and antimutators compete during the evolution of mutator cells
Tracy, M.; Lee, M.; Hearn, B.; Dowsett, I.; Thurber, L.; Loo, J.; Loeb, A. M.; Preston, K.; Tuncel, M.; Ghodsian, N.; Bode, A.; Tang, T.; Chia, A. R.; Herr, A. J.
10.1101/718163 — cancer biology — Posted on 2020-05-09
3762 On spatial molecular arrangements of SARS-CoV2 genomes of Indian patients
Hassan, S. S.; Moitra, A.; Rout, R. K.; Choudhury, P. P.; Pramanik, P.; Jana, S. S.
10.1101/2020.05.01.071985 — bioinformatics — Posted on 2020-05-09
3766 Suicidal thoughts, behaviors, and event-related potentials: A meta-analysis
Gallyer, A. J.; Dougherty, S. P.; Burani, K.; Albanese, B. J.; Joiner, T. E.; Hajcak, G.
10.1101/2020.04.29.069005 — neuroscience — Posted on 2020-05-09
3767 mir-21 is associated with inactive low molecular weight Argonaute complexes in thyroid cancer cell lines
Powell, B. H.; Turchinovich, A.; Wang, Y.; Liao, Z.; Aasif Dar, M.; La Rocca, G.; Umanah, G. E.; Zeiger, M. A.; Umbricht, C. B.; Witwer, K. W.
10.1101/2020.03.24.006072 — molecular biology — Posted on 2020-05-09
3768 The non-typeable Haemophilus influenzae major adhesin Hia is a dual function lectin that binds to human-specific respiratory tract sialic acid glycan receptors.
Atack, J. M.; Day, C. J.; Poole, J.; Brockman, K.; Timms, J. R. L.; Winter, L.; Haselhorst, T.; Bakaletz, L. O.; Barenkamp, S. J.; Jennings, M. P.
10.1101/2020.05.08.084038 — microbiology — Posted on 2020-05-09
3770 Phage recombination drives evolution of spore-forming Bacilli
Dragos, A.; B, P.; Hasan, Z.; Lenz-Strube, M.; Kempen, P. J.; Maroti, G.; Kaspar, C.; Bose, B.; Burton, B.; Bischofs, I. B.; Kovacs, A. T.
10.1101/2020.05.06.055103 — microbiology — Posted on 2020-05-09
3772 Fine-scale genomic analyses of admixed individuals reveal unrecognized genetic ancestry components in Argentina
Luisi, P.; Garcia, A.; Berros, J. M.; Motti, J.; Demarchi, D.; Alfaro, E.; Aquilano, E.; Argüelles, C.; Avena, S.; Bailliet, G.; Beltramo, J.; Bravi, C.; Cuello, M.; Dejean, C.; Dipierri, J. E.; Jurado Medina, L.; Lanata, J. L.; Muzzio, M.; Parolin, M. L.; Pauro, M.; Paz Sepulveda, P. B.; Rodriguez Golpe, D.; Santos, M. R.; Schwab, M.; Silverio, N.; Zubrzycki, J.; Ramallo, V.; Dopazo, H.
10.1101/2020.01.24.917898 — genetics — Posted on 2020-05-09
3776 First-principles prediction of the information processing capacity of a simple genetic circuit
Razo-Mejia, M.; Marzen, S.; Chure, G. D.; Taubman, R.; Morrison, M.; Phillips, R.
10.1101/594325 — biophysics — Posted on 2020-05-09
3779 Defensin driven viral evolution
Diaz, K.; Hu, C. T.; Sul, Y.; Bromme, B. A.; Myers, N. D.; Skorohodova, K. V.; Gounder, A. P.; Smith, J. G.
10.1101/2020.05.08.079574 — microbiology — Posted on 2020-05-09
3782 Whole Genome Sequences of Aedes aegypti (Linn.) Field Isolates from Southern India
Bernard, V.; Moudgalya, S.; Reegan, D.; Sreekanthreddy, P.; Mohan, A.; Subramanya, H. S.; Vembar, S. S.; Ghosh, S.
10.1101/2020.05.08.083949 — genomics — Posted on 2020-05-09
3783 A rapid, low cost, and highly sensitive SARS-CoV-2 diagnostic based on whole genome sequencing
Glenn St Hilaire, B.; Durand, N. C.; Mitra, N.; Godinez Pulido, S.; Mahajan, R.; Blackburn, A.; Colaric, Z. L.; Theisen, J. W. M.; Weisz, D.; Dudchenko, O.; Gnirke, A.; Rao, S. S. P.; Kaur, P.; Aiden, E. L.; Aiden, A. P.
10.1101/2020.04.25.061499 — genomics — Posted on 2020-05-09
3784 Geographic and environmental contributions to genomic divergence in mangrove forests
Silva, M. F. d.; Cruz, M. V.; Junior, J. d. D. V.; Zucchi, M. I.; Mori, G. M.; de Souza, A. P.
10.1101/2020.01.08.889717 — evolutionary biology — Posted on 2020-05-09
3787 The loss of the pyoverdine secondary receptor in Pseudomonas aeruginosa results in a fitter strain suitable for population invasion
Gonzalez, J.; Salvador, M.; Ozkayab, O.; Spick, M.; Costa, C.; Bailey, M. J.; Avignone Rossa, C.; Kuemmerli, R.; Jimenez, J. I.
10.1101/2020.05.08.085159 — microbiology — Posted on 2020-05-09
3789 YTHDF1 drives intestinal immune response against bacterial infection
Wang, Y.; Zong, X.; Xiao, X.; Shen, B.; Jiang, Q.; Wang, H.; Lu, Z.; Wang, F.; Jing, M.
10.1101/2020.05.08.083840 — immunology — Posted on 2020-05-09
3792 Assessing the variation within the oral microbiome of healthy adults
Nearing, J. T.; DeClercq, V.; Van Limbergen, J.; Langille, M. G. I.
10.1101/2020.05.07.083634 — microbiology — Posted on 2020-05-09
3793 Whole genome and phylogenetic analysis of SARS-CoV-2 strains from the index and early patients with COVID-19 in Dubai, United Arab Emirates, 29 January to 18 March 2020
Abou Tayoun, A.; Loney, T.; Khansaheb, H.; Ramaswamy, S.; Harilal, D.; Deesi, Z.; Varghese, R.; Al Suwaidi, H.; Alkhajeh, A.; AlDabal, L.; Uddin, M.; Senok, A.; Hamoudi, R.; Halwani, R.; Hamid, Q.; Nowotny, N.; Alsheikh-Ali, A.
10.1101/2020.05.06.080606 — genomics — Posted on 2020-05-08
3797 Massive Multiplexing Can Deliver a $1 Test for COVID-19
Hebert, P. D.; Prosser, S. W.; Ivanova, N. V.; Zakharov, E. V.; Ratnasingham, S.
10.1101/2020.05.05.079400 — genomics — Posted on 2020-05-08
3800 Identification of neutralizing human monoclonal antibodies from Italian Covid-19 convalescent patients
Andreano, E.; Nicastri, E.; Paciello, I.; Pileri, P.; Manganaro, N.; Piccini, G.; Manenti, A.; Troisi, M.; Vacca, F.; Pantano, E.; De Santi, C.; Cardamone, D.; Kabanova, A.; Agrati, C.; Castilletti, C.; Capobianchi, M. R.; Emiliozzi, A.; Fabbiani, M.; Montagnani, F.; Montomoli, E.; Sala, C.; Ippolito, G.; Rappuoli, R.
10.1101/2020.05.05.078154 — immunology — Posted on 2020-05-08
3801 A phylodynamic workflow to rapidly gain insights into the dispersal history and dynamics of SARS-CoV-2 lineages
Dellicour, S.; Durkin, K.; Hong, S. L.; Vanmechelen, B.; Marti-Carreras, J.; Gill, M. S.; Meex, C.; Bontems, S.; Andre, E.; Gilbert, M.; Walker, C.; De Maio, N.; Hadfield, J.; Hayette, M.-P.; Bours, V.; Wawina-Bokalanga, T.; Artesi, M.; Baele, G.; Maes, P.
10.1101/2020.05.05.078758 — evolutionary biology — Posted on 2020-05-08
3805 A potent neutralizing human antibody reveals the N-terminal domain of the Spike protein of SARS-CoV-2 as a site of vulnerability
Chi, X.; Yan, R.; Zhang, J.; Zhang, G.; Zhang, Y.; Hao, M.; Zhang, Z.; Fan, P.; Dong, Y.; Yang, Y.; Chen, Z.; Guo, Y.; Zhang, J.; Li, Y.; Song, X.; Chen, Y.; Xia, L.; Fu, L.; Hou, L.; Xu, J.; Yu, C.; Li, J.; Zhou, Q.; Chen, W.
10.1101/2020.05.08.083964 — biochemistry — Posted on 2020-05-08
3806 Efficacy of a novel iodine complex solution, CupriDyne, in inactivating SARS-CoV-2
Mantlo, E. K.; Evans, A.; Patterson-Fortin, L.; Boutros, J.; Smith, R.; Paessler, S.
10.1101/2020.05.08.082701 — microbiology — Posted on 2020-05-08
3808 Mitochondrial cytochrome c liberates the nucleophosmin-sequestered ARF tumor suppressor in the nucleolus
Gonzalez-Arzola, K.; Diaz-Quintana, A.; Bernardo-Garcia, N.; Casado-Combreras, M. A.; Elena-Real, C. A.; Velazquez-Cruz, A.; Gil-Caballero, S.; Velazquez-Campoy, A.; Szulc, E.; Ayala, I.; Arranz, R.; Salvatella, X.; Valpuesta, J. M.; Hermoso, J. A.; De la Rosa, M. A.; Diaz-Moreno, I.
10.1101/2020.05.07.057075 — biophysics — Posted on 2020-05-08
3811 Methods for quantitative susceptibility and R2* mapping in whole post-mortem brains at 7T
Wang, C.; Foxley, S.; Ansorge, O.; Bangerter-Christensen, S.; Chiew, M.; Leonte, A.; Menke, R. A.; Mollink, J.; Pallebage-Gamarallage, M.; Turner, M. R.; Miller, K. L.; Tendler, B. C.
10.1101/2020.05.07.082479 — neuroscience — Posted on 2020-05-08
3815 Reversing age: dual species measurement of epigenetic age with a single clock
Horvath, S.; Singh, K.; Raj, K.; Khairnar, S.; Sanghavi, A.; Shrivastava, A.; Zoller, J. A.; Li, C. Z.; Herenu, C.; Canatelli-Mallat, M.; Lehmann, M.; Solberg-Woods, L.; Garcia Martinez, A.; Wang, T.; Chiavellini, P.; Levine, A. J.; Chen, H.; Goya, R. G.; Katcher, H. L.
10.1101/2020.05.07.082917 — developmental biology — Posted on 2020-05-08
3817 Tradeoffs between mobility and infectiousness in the spatial spread of an emerging pathogen
Langwig, K. E.; White, J. P.; Parise, K. L.; Kaarakka, H. M.; Redell, J. A.; DePue, J. E.; Scullon, W. H.; Foster, J. T.; Kipatrick, A. M.; Hoyt, J. R.
10.1101/2020.05.07.082651 — ecology — Posted on 2020-05-08
3819 A metabolic CRISPR-Cas9 screen in Chinese hamster ovary cells identifies glutamine-sensitive genes
Karottki, K. J. l. C.; Hefzi, H.; Li, S.; Pedersen, L. E.; Spahn, P.; Ruckerbauer, D.; Bort, J. H.; Thomas, A.; Lee, J. S.; Borth, N.; Lee, G. M.; Kildegaard, H. F.; Lewis, N. E.
10.1101/2020.05.07.081604 — bioengineering — Posted on 2020-05-08
3821 Diversity and composition of gut microbiome of cervical cancer patients by 16S rRNA and whole-metagenome sequencing
Biegert, G.; Karpinets, T.; Wu, X.; El Alam, M. B.; Sims, T. T.; Yoshida-Court, K.; Lynn, E. J.; Yue, J.; Delgado Medrano, A.; Petrosino, J.; Mezzari, M. P.; Ajami, N. J.; Solley, T.; Ahmed-Kaddar, M.; Colbert, L. E.; Klopp, A. H.
10.1101/2020.05.05.080002 — microbiology — Posted on 2020-05-08
3822 A low-cost pipeline for soil microbiome profiling
Bollmann-Giolai, A.; Giolai, M.; Heavens, D.; Macaulay, I. C.; Malone, J. G.; Clark, M. D.
10.1101/2020.05.07.082305 — genomics — Posted on 2020-05-08
3823 Colorectal adenocarcinomas downregulate the mitochondrial Na+/Ca2+ exchanger NCLX to drive metastatic spread
Pathak, T.; Gueguinou, M.; Walter, V.; Delierneux, C.; Johnson, M. T.; Zhang, X.; Xin, P.; Yoast, R. E.; Emrich, S. M.; Yochum, G. S.; Sekler, I.; Koltun, W. A.; Gill, D. L.; Hempel, N.; Trebak, M.
10.1101/2020.05.07.083071 — cancer biology — Posted on 2020-05-08
3825 Novel NGS Pipeline for Virus Discovery from a Wide Spectrum of Hosts and Sample Types
Plyusnin, I.; Kant, R.; Jaaskelainen, A. J.; Sironen, T.; Holm, L.; Vapalahti, O.; Smura, T.
10.1101/2020.05.07.082107 — bioinformatics — Posted on 2020-05-08
3826 Werewolf, there wolf: variants in Hairless associated with hypotrichia and roaning in the lykoi cat breed
Buckley, R. M.; Gandolfi, B.; Creighton, E. K.; Pyne, C. A.; LeRoy, M. L.; Senter, D. A.; Bouhan, D. M.; Gobble, J. R.; Abitbol, M.; Lyons, L. A.; 99 Lives Consortium,
10.1101/2020.05.07.082719 — genetics — Posted on 2020-05-08
3828 Diverse deep neural networks all predict human IT well, after training and fitting
Storrs, K. R.; Kietzmann, T. C.; Walther, A.; Mehrer, J.; Kriegeskorte, N.
10.1101/2020.05.07.082743 — neuroscience — Posted on 2020-05-08
3829 Conservative route to extreme genome compaction in a miniature annelid
Martin-Duran, J. M.; Vellutini, B.; Marletaz, F.; Cetrangolo, V.; Cvetesic, N.; Thiel, D.; Henriet, S.; Grau-Bove, X.; Carrillo-Baltodano, A.; Gu, W.; Kerbl, A.; Marquez, Y.; Bekkouche, N.; Chourrout, D.; Gomez-Skarmeta, J.-L.; Irimia, M.; Lenhard, B.; Worsaae, K.; Hejnol, A.
10.1101/2020.05.07.078311 — genomics — Posted on 2020-05-08
3830 No Difference in 2D:4D Ratio between Youth with Elevated Prenatal Androgen Exposure due to Congenital Adrenal Hyperplasia and Controls
Nave, G.; Koppin, C. M.; Manfredi, D.; Richards, G.; Watson, S. J.; Geffner, M. E.; Yong, J. E.; Kim, R.; Ross, H. M.; Serrano-Gonzalez, M. S.-G.; Kim, M. S.
10.1101/2020.05.07.082529 — developmental biology — Posted on 2020-05-08
3831 Proteome-Wide Analysis of ADAR-mediated Messenger RNA Editing During Fruit Fly Ontogeny
Kliuchnikova, A. A.; Goncharov, A. O.; Levitsky, L. I.; Pyatnitskiy, M. A.; Novikova, S. E.; Kuznetsova, K. G.; Ivanov, M. V.; Ilina, I. Y.; Farafonova, T. E.; Zgoda, V. G.; Gorshkov, M. V.; Moshkovskii, S. A.
10.1101/2020.05.07.082404 — systems biology — Posted on 2020-05-08
3833 Screening for New Interaction Partners for a Group IIB Intron Ribozyme with Surface Plasmon Resonance Imaging Coupled to MALDI Mass Spectrometry
Anders, U.; Gulotti-Georgieva, M.; Zelger-Paulus, S.; Hibti, F.-E.; Frydman, C.; Suckau, D.; Sigel, R. K. O.; Zenobi, R.
10.1101/2020.05.07.082776 — molecular biology — Posted on 2020-05-08
3834 Robust decomposition of cell type mixtures in spatial transcriptomics
Cable, D. M.; Murray, E.; Zou, L. S.; Goeva, A.; Macosko, E. Z.; Chen, F.; Irizarry, R. A.
10.1101/2020.05.07.082750 — genomics — Posted on 2020-05-08
3835 Thermogenic genes are blunted whereas brown adipose tissue identity is preserved in human obesity
Jespersen, N. Z.; Andersen, M. W.; Jensen, V. H.; Staerker, T. W.; Severinsen, M. C.; Peijs, L.; Soares, R.; Forss, I.; Andersen, E. S.; Hahn, C. H.; Homee, P.; Mandrup, S.; Pedersen, B. K.; Nielsen, S.; Scheele, C.
10.1101/2020.05.07.082057 — cell biology — Posted on 2020-05-08
3836 A kinetic ensemble of the Alzheimer's Aβ peptide
Löhr, T.; Kohlhoff, K.; Heller, G. T.; Camilloni, C.; Vendruscolo, M.
10.1101/2020.05.07.082818 — biophysics — Posted on 2020-05-08
3839 Efficient Estimation of Large-Scale Spatial Capture-Recapture Models
Turek, D.; Milleret, C.; Ergon, T.; Broseth, H.; de Valpine, P.
10.1101/2020.05.07.081182 — ecology — Posted on 2020-05-08
3840 CD8 T cells induce destruction of bone marrow stromal niches and hematopoietic stem cell dysfunction in chronic viral infections
Isringhausen, S.; Kovtonyuk, L.; Suessbier, U.; Krautler, N.; Gomariz, A.; Helbling, P. M.; Chyn Wong, H.; Nagasawa, T.; Manz, M. G.; Oxenius, A.; Nombela-Arrieta, C.
10.1101/2020.05.07.076083 — immunology — Posted on 2020-05-08
3841 Single-cell atlas of human developing and azoospermia patients' testicles reveals the roadmap and defects in somatic microenvironment
Zhao, L.; Yao, C.; Xing, X.; Jing, T.; Li, P.; Zhu, Z.; Yang, C.; Zhai, J.; Tian, R.; Chen, H.; Luo, J.; Liu, N.; Deng, Z.; Lin, X.; Li, N.; Fang, J.; Sun, J.; Wang, C.; Zhou, Z.; Li, Z.
10.1101/2020.05.07.082024 — developmental biology — Posted on 2020-05-08
3842 3D additive manufactured composite scaffolds with antibiotic-loaded lamellar fillers for bone infection prevention and tissue regeneration
Camara Torres, M.; Duarte, S.; Sinha, R.; Egizabal, A.; Alvarez, N.; Bastianini, M.; Sisani, M.; Scopece, P.; Scatto, M.; Bonetto, A.; Marcomini, A.; Sanchez, A.; Patelli, A.; Mota, C.; Moroni, L.
10.1101/2020.05.07.082495 — bioengineering — Posted on 2020-05-08
3844 Analysis of SARS-CoV-2 Antibodies in COVID-19 Convalescent Blood using a Coronavirus Antigen Microarray
de Assis, R. R.; Jain, A.; Nakajima, R.; Jasinskas, A.; Felgner, J.; Obiero, J. M.; Adenaiye, O. O.; Tai, S.; Hong, F. H.; Norris, P.; Stone, M.; Simmons, G.; Bagri, A.; Schreiber, M.; Buser, A.; Holbro, A.; Battegay, M.; Hosimer, P.; Noesen, C.; Milton, D. K.; Prometheus Study Group, ; Davies, H.; Contestable, P.; Corash, L. M.; Busch, M. P.; Felgner, P. L.; Khan, S.
10.1101/2020.04.15.043364 — immunology — Posted on 2020-05-08
3846 Rapid community-driven development of a SARS-CoV-2 tissue simulator
Wang, Y.; An, G.; Becker, A.; Cockrell, C.; Collier, N.; Craig, M.; Davis, C. L.; Faeder, J.; Ford Versypt, A. N.; Gianlupi, J. F.; Glazier, J. A.; Heiland, R.; Hillen, T.; Islam, M. A.; Jenner, A.; Liu, B.; Morel, P.; Narayanan, A.; Ozik, J.; Rangamani, P.; Shoemaker, J. E.; Smith, A. M.; Macklin, P.
10.1101/2020.04.02.019075 — systems biology — Posted on 2020-05-08
3847 Heparin inhibits cellular invasion by SARS-CoV-2: structural dependence of the interaction of the surface protein (spike) S1 receptor binding domain with heparin.
Mycroft-West, C.; Su, D.; Pagani, I.; Rudd, T.; Elli, S.; Guimond, S.; Miller, G.; Meneghetti, M.; Nader, H.; Li, Y.; Nunes, Q.; Procter, P.; Mancini, N.; Clementi, M.; Bisio, A.; Forsyth, N.; Turnbull, J.; Guerrini, M.; Fernig, D.; Vicenzi, E.; Yates, E.; Lima, M.; Skidmore, M. A.
10.1101/2020.04.28.066761 — biochemistry — Posted on 2020-05-08
3848 A temperature-dependent translational switch controls biofilm development in Vibrio cholerae
del Peso Santos, T.; Blake, J.; Sit, B.; Warr, A. R.; Benes, V.; Waldor, M. K.; Cava, F.
10.1101/2020.05.07.082040 — microbiology — Posted on 2020-05-08
3853 Lack of adaptation to centriolar defects leads to p53-independent microcephaly in the absence of Cep135
Malumbres, M.; Gonzalez-Martinez, J.; Cwersch, A.; Martinez-Alonso, D.; Lopez, L. R.; Almagro, J.; Megias, D.; Boskovic, J.; Gilabert, J.; Grana Castro, O.; Pierani, A.; Behrens, A.; Ortega, S.
10.1101/2020.05.07.082032 — cell biology — Posted on 2020-05-08
3854 A gas-and-brake mechanism of bHLH proteins modulates shade avoidance in Arabidopsis thaliana
Buti, S.; Pantazopoulou, C. K.; Hoogers, V. A. C.; van Gelderen, K.; Reinen, E.; Pierik, R.
10.1101/2020.05.07.082735 — plant biology — Posted on 2020-05-08
3857 The actin-modulating protein Synaptopodin mediates long-term survival of dendritic spines
Yap, K.; Drakew, A.; Smilovic, D.; Rietsche, M.; Vuksic, M.; Del Turco, D.; Deller, T.
10.1101/2020.05.08.080374 — neuroscience — Posted on 2020-05-08
3862 Light affects behavioral despair involving the clock gene Period 1
Olejniczak, I.; Ripperger, J. A.; Sandrelli, F.; Schnell, A.; Mansencal-Strittmatter, L.; Hui, K. Y.; Brenna, A.; Benfredj, N.; Albrecht, U.
10.1101/2020.05.07.082156 — genetics — Posted on 2020-05-08
3863 Warming-enhanced priority effects at population and community levels in aquatic bacteria
Vass, M.; Szekely, A. J.; Lindström, E. S.; Osman, O. A.; Langenheder, S.
10.1101/2020.01.27.921726 — ecology — Posted on 2020-05-08
3864 AI-based identification of grain cultivars via non-target mass spectrometry
Nichani, K.; Uhlig, S.; Colson, B.; Hettwer, K.; Simon, K.; Bönick, J.; Uhlig, C.; Rawel, H. M.; Stoyke, M.; Gowik, P.; Huschek, G.
10.1101/2020.05.07.082065 — bioinformatics — Posted on 2020-05-08
3865 Shoot and root thermomorphogenesis are linked by a developmental trade-off
Gaillochet, C.; Burko, Y.; Platre, M. P.; Zhang, L.; Simura, J.; Kumar, V.; Ljung, K.; Chory, J.; Busch, W.
10.1101/2020.05.07.083246 — plant biology — Posted on 2020-05-08
3866 Personality and local brain structure: their shared genetic basis and reproducibility.
Valk, S. L.; Hoffstaedter, F.; Camilleri, J.; Kochunov, P.; Yeo, B. T. T.; Eickhoff, S. B.
10.1101/645945 — neuroscience — Posted on 2020-05-08
3868 Plasmids shape the diverse accessory resistomes of Escherichia coli ST131
Decano, A. G.; Tran, N.; Al-Foori, H.; Al-Awadi, B.; Leigh Campbell, L.; Ellison, K.; Mirabueno, L. P.; Nelson, M.; Power, S.; Smith, G.; Smyth, C.; Vance, Z.; Rahm, A.; Downing, T.
10.1101/2020.05.07.081380 — genomics — Posted on 2020-05-08
3871 Machine learning with biomedical ontologies
Kulmanov, M.; Smaili, F. Z.; Gao, X.; Hoehndorf, R.
10.1101/2020.05.07.082164 — bioinformatics — Posted on 2020-05-08
3872 ampir: an R package for fast genome-wide prediction of antimicrobial peptides
Fingerhut, L. C.; Miller, D. J.; Strugnell, J. M.; Daly, N. L.; Cooke, I. R.
10.1101/2020.05.07.082412 — bioinformatics — Posted on 2020-05-08
3873 Transcriptomic response of an Antarctic yeast Rhodotorula sp. USM-PSY62 to temperature changes
Chai, C.-N.; Yam, H.-C.; Rosli, N.; Azlan, A.; Azzam, G.; Abdul Halim, M.; Najimudin, N.
10.1101/2020.05.07.080796 — bioinformatics — Posted on 2020-05-08
3875 Endophilin A1 promotes Actin Polymerization in response to Ca2+/calmodulin to Initiate Structural Plasticity of Dendritic Spines
Liu, J.-J.; Yang, Y.; Chen, J.; Chen, X.; Li, D.; He, J.; Zhao, S.; Yang, X.; Deng, S.; Wang, D.; Guo, Z.; Zhu, S.; Li, D.; Ma, C.; Liang, X.; Shi, Y. S.
10.1101/2020.05.07.082081 — cell biology — Posted on 2020-05-08
3878 Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease
Ma, C.; Sacco, M. D.; Hurst, B.; Townsend, J. A.; Hu, Y.; Szeto, T.; Zhang, X.; Tarbet, B.; Marty, M. T.; Chen, Y.; Wang, J.
10.1101/2020.04.20.051581 — pharmacology and toxicology — Posted on 2020-05-08
3882 Cell-type specific in vitro gene expression profiling of stem-cell derived neural models
Gregory, J. A.; Hoelzli, E.; Abdelaal, R.; Braine, C.; Cuevas, M.; Halpern, M.; Kang, K.; Barretto, N.; Akbalik, G.; Schrode, N.; Cheng, E.; Bowles, K. R.; Lotz, S.; Goderie, S.; Karch, C.; Goate, A. M.; temple, S.; Brennand, K.; Phatnani, H.
10.1101/2020.04.30.064709 — genomics — Posted on 2020-05-08
3889 Pazopanib induces dramatic but transient contraction of myeloid suppression compartment in favor of adaptive immunity
Rinchai, D.; Verzoni, E.; Huber, V.; Cova, A.; Squarcina, P.; Cecco, L. D.; Braud, F. d.; Ratta, R.; Dugo, M.; Lalli, L.; Vallacchi, V.; Rodolfo, M.; Roelands, J.; Castelli, C.; Chaussabel, D.; Procopio, G.; Bedognetti, D.; Rivoltini, L.
10.1101/2020.05.01.071613 — cancer biology — Posted on 2020-05-08
3891 Host evolutionary history and ecology shape virome composition in fishes
Geoghegan, J. L.; Di Giallonardo, F.; Wille, M.; Ortiz-Baez, A. S.; Costa, V. A.; Ghaly, T.; Mifsud, J. C.; Turnbull, O. M.; Bellwood, D. R.; Williamson, J. E.; Holmes, E. C.
10.1101/2020.05.06.081505 — microbiology — Posted on 2020-05-08
3894 Functional brain age prediction suggests accelerated aging in preclinical familial Alzheimer's disease, irrespective of fibrillar amyloid-beta pathology
Gonneaud, J.; Baria, A. T.; Pichet Binette, A.; Gordon, B. A.; Chhatwal, J. P.; Cruchaga, C.; Jucker, M.; Levin, J.; Salloway, S.; Farlow, M.; Gauthier, S.; Benzinger, T. L.; Morris, J. C.; Bateman, R. J.; Breitner, J. C. S.; Poirier, J.; Vachon-Presseau, E.; Villeneuve, S.; Alzheimer's Disease Neuroimaging Initiative (ADNI), ; Dominantly Inherited Alzheimer Network (DIAN), ; PREVENT-AD Research Group,
10.1101/2020.05.06.076745 — neuroscience — Posted on 2020-05-08
3896 FMRP Links Optimal Codons to mRNA stability in Neurons
Shu, H. R.; Donnard, E.; Liu, B.; Wang, R.; Richter, J.
10.1101/801449 — molecular biology — Posted on 2020-05-08
3897 Rapid diagnosis of SCA36 in a three-generation family using short-read whole genome sequencing data
Rafehi, H.; Szmulewicz, D. J.; Pope, K.; Wallis, M.; Christodoulou, J.; White, S. M.; Delatycki, M.; Lockhart, P. J.; Bahlo, M.
10.1101/851675 — genomics — Posted on 2020-05-08
3903 Skin Delivery of Modified Vaccinia Ankara Viral Vectors Generates Superior T Cell Immunity Against a Respiratory Viral Challenge
Pan, Y.; Liu, L.; Tian, T.; Zhao, J.; Park, C. O.; Lofftus, S. Y.; Stingley, C. A.; Mei, S.; Liu, X.; Kupper, T. S.
10.1101/2020.05.06.079046 — immunology — Posted on 2020-05-08
3904 Causal Inference for Heritable Phenotypic Risk Factors Using Heterogeneous Genetic Instruments
Wang, J.; Zhao, Q.; Bowden, J.; Hemani, G.; Smith, G. D.; Small, D.; Zhang, N. R.
10.1101/2020.05.06.077982 — genetics — Posted on 2020-05-08
3906 Systemic immune dysfunction in cancer patients driven by IL6 and IL8 induction of an inhibitory receptor module in peripheral CD8+ T cells
Somasundaram, A.; Cillo, A. R.; Lampenfeld, C.; Oliveri, L.; Velez, M. A.; Joyce, S.; Calderon, M. J.; Dadey, R.; Rajasundaram, D.; Normolle, D. P.; Watkins, S. C.; Herman, J. G.; Kirkwood, J. M.; Lipson, E. J.; Ferris, R. L.; Bruno, T. C.; Vignali, D. A. A.
10.1101/2020.05.06.081471 — cancer biology — Posted on 2020-05-08
3907 Cancer-associated hypersialylated MUC1 drives the differentiation of monocytes into macrophages with a pathogenic phenotype
Beatson, R.; Graham, R.; Grundland Freile, F.; Cozzetto, D.; Kannambath, S.; Pfeifer, E.; Woodman, N.; Owen, J.; Nuamah, R.; Mandel, U.; Pinder, S.; Gillett, C.; Noll, T.; Bouybayoune, I.; Taylor-Papadimitriou, J.; Burchell, J. M.
10.1101/2020.05.06.080713 — cancer biology — Posted on 2020-05-08
3909 DMT alters cortical travelling waves
Alamia, A.; Timmermann, C.; VanRullen, R.; Carhart-Harris, R.
10.1101/2020.05.06.080937 — neuroscience — Posted on 2020-05-08
3910 Mutations in MYLPF cause a novel segmental amyoplasia that manifests as distal arthrogryposis
Chong, J. X.; Talbot, J. C.; Teets, E. M.; Previs, S.; Martin, B. L.; Shively, K. M.; Marvin, C. T.; Aylsworth, A. S.; Saadeh-Haddad, R.; Schatz, U. A.; Inzana, F.; Ben-Omran, T.; Almusafri, F.; Al-Mulla, M.; Buckingham, K. J.; Harel, T.; Mor-Shaked, H.; Radhakrishnan, P.; Girisha, K. M.; Nayak, S. S.; Shukla, A.; Dieterich, K.; Faure, J.; Rendu, J.; Capri, Y.; Latypova, X.; Nickerson, D. A.; Warshaw, D.; Janssen, P. M.; University of Washington Center for Mendelian Genomics, ; Amacher, S. L.; Bamshad, M. J.
10.1101/2020.05.06.071555 — genetics — Posted on 2020-05-08
3912 Nintedanib Targets KIT D816V Neoplastic Cells Derived from Induced Pluripotent Stem cells of Systemic Mastocytosis
Szymanski de Toledo, M. A.; Gatz, M.; Sontag, S.; Gleixer, K. V.; Eisenwort, G.; Feldberg, K.; Kluge, F.; Guareschi, R.; Rossetti, G.; Sechi, A. S.; Dufva, O.; Mustjoki, S. M.; Maurer, A.; Schueler, H. M.; Goetzke, R.; Braunschweig, T.; Simonowski, A.; Panse, J. P.; Jawhar, M.; Reiter, A.; Hilberg, F.; Ettmayer, P.; Wagner, W.; Koschmieder, S.; Bruemmendorf, T. H.; Valent, P.; Chatain, N.; Zenke, M.
10.1101/2020.05.06.080150 — cancer biology — Posted on 2020-05-08
3913 Temporal correlation between oscillating force dipoles drives single cell migration in 3D.
Godeau, A.; Leoni, M. P.; Comelles, J.; Delanoe-Ayari, H.; Ott, A.; Harlepp, S.; Sens, P.; Riveline, D.
10.1101/2020.05.07.081984 — biophysics — Posted on 2020-05-08
3919 Bacterial evolution in high osmolarity environments
Cesar, S.; Anjur-Dietrich, M.; Yu, B.; Li, E.; Rojas, E.; Neff, N.; Cooper, T. F.; Huang, K. C.
10.1101/2020.05.07.081752 — microbiology — Posted on 2020-05-08
3920 Characterization Of Ancestral Origin Of Cystic Fibrosis Of Patients With New Reported Mutations In CFTR
Paz-y-Mino, C.; Zambrano, A. K.; Ruiz-Cabezas, J. C.; Armendariz-Castillo, I.; Garcia-Cardenas, J. M.; Guerrero, S.; Lopez-Cortes, A.; Perez-Villa, A.; Guevara-Ramirez, P.; Yumiceba, V.; Leone, P. E.
10.1101/2020.05.06.081653 — genetics — Posted on 2020-05-08
3921 Requirement for Anti-Apoptotic MCL-1 during Early Erythropoiesis
Turnis, M. E.; Kaminska, E.; Smith, K. H.; Kartchner, B. J.; Vogel, P.; Laxton, J. D.; Ashmun, R. A.; Ney, P. A.; Opferman, J. T.
10.1101/2020.05.06.081422 — developmental biology — Posted on 2020-05-08
3922 Epithelial-mesenchymal transition sensitizes breast cancer cells to cell death via the fungus-derived sesterterpenoid ophiobolin A
Reisenauer, K. N.; Tao, Y.; Song, S.; Patel, S.; Ingros, A.; Sheesley, P.; Masi, M.; Boari, A.; Taube, J. H.; Evidente, A.; Kornienko, A.; Romo, D.
10.1101/2020.05.06.079343 — cancer biology — Posted on 2020-05-08
3924 Spatial heterogeneity of cell-matrix adhesive forces predicts human glioblastoma migration
Rezk, R.; Jia, B. Z.; Wendler, A.; Dimov, I.; Watts, C.; Markaki, A. E.; Kabla, A.; Franze, K.
10.1101/2020.05.06.080804 — biophysics — Posted on 2020-05-08
3926 Haplocheck: Phylogeny-based Contamination Detection in Mitochondrial and Whole-Genome Sequencing Studies
Weissensteiner, H.; Forer, L.; Fendt, L.; Kheirkhah, A.; Salas, A.; Kronenberg, F.; Schoenherr, S.
10.1101/2020.05.06.080952 — bioinformatics — Posted on 2020-05-08
3928 CheckV: assessing the quality of metagenome-assembled viral genomes
Nayfach, S.; Camargo, A. P.; Eloe-Fadrosh, E.; Roux, S.; Kyrpides, N.
10.1101/2020.05.06.081778 — bioinformatics — Posted on 2020-05-08
3929 Selective Plane Illumination Microscopy and Computing Reveal Differential Obliteration of Retinal Vascular Plexuses
Chang, C.-C.; Chu, A.; Meyer, S.; Sun, M. M.; Abiri, P.; Baek, K. I.; Gudapati, V.; Ding, X.; Guihard, P.; Ding, Y.; Bostrom, K. I.; Li, S.; Gordon, L. K.; Zheng, J. J.; Hsiai, T. K.
10.1101/2020.05.06.081463 — bioengineering — Posted on 2020-05-08
3935 Task-driven hierarchical deep neural networkmodels of the proprioceptive pathway
Sandbrink, K. J.; Mamidanna, P.; Michaelis, C.; Mathis, M. W.; Bethge, M.; Mathis, A.
10.1101/2020.05.06.081372 — neuroscience — Posted on 2020-05-08
3936 Detailed temporal dissection of an enhancer cluster reveals two distinct roles for individual elements
Thomas, H.; Kotova, E.; Pilz, A.; Romeike, M.; Lackner, A.; Bock, C.; Leeb, M.; Wysocka, J.; Buecker, C.
10.1101/2020.05.06.080564 — molecular biology — Posted on 2020-05-08
3938 Identification of Lipid Droplets in Gut Microbiota
Zhang, K.; Zhou, C.; Zhou, Z.; Li, X.; Li, Z.; Zhang, M.; Zhang, X.; Zhang, C.; Wei, T.; Zhang, S.; Liu, P.
10.1101/2020.05.06.080317 — microbiology — Posted on 2020-05-08
3940 Promoter activity-based case-control association study on SLC6A4 highlighting hypermethylation and altered amygdala volume in male patients with schizophrenia
Ikegame, T.; Bundo, M.; Okada, N.; Murata, Y.; Koike, S.; Sugawara, H.; Saito, T.; Ikeda, M.; Owada, K.; Fukunaga, M.; Yamashita, F.; Koshiyama, D.; Natsubori, T.; Iwashiro, N.; Asai, T.; Yoshikawa, A.; Nishimura, F.; Kawamura, Y.; Ishigooka, J.; Kakiuchi, C.; Sasaki, T.; Abe, O.; Hashimoto, R.; Iwata, N.; Yamasue, H.; Kato, T.; Kasai, K.; Iwamoto, K.
10.1101/2020.05.06.058792 — genetics — Posted on 2020-05-08
3943 Pretreatment of aged mice with retinoic acid restores alveolar regeneration via upregulation of reciprocal PDGFRA signaling
Gokey, J.; Snowball, J.; Green, J.; Waltamath, M.; Spinney, J. J.; Black, K. E.; Hariri, L. P.; Xu, Y.; Perl, A.-K. T.
10.1101/2020.05.06.080994 — cell biology — Posted on 2020-05-08
3945 Structural, in silico, and functional analysis of a Disabled-2-derived peptide for recognition of sulfatides
Song, W.; Gottschalk, C. J.; Tang, T.-X.; Biscardi, A.; Ellena, J. F.; Finkielstein, C. V.; Brown, A. M.; Capelluto, D. G. S.
10.1101/2020.05.06.081299 — biophysics — Posted on 2020-05-08
3946 A mouse bio-electronic nose for sensitive and versatile chemical detection
Shor, E.; Herrero-Vidal, P.; Dewan, A.; Uguz, I.; Curto, V. F.; Malliaras, G. G.; Savin, C.; Bozza, T.; Rinberg, D.
10.1101/2020.05.06.079772 — bioengineering — Posted on 2020-05-08
3947 Detect Genomic G-Quadruplexes in Living Animal Cells with a Tiny Artificial Protein Probe
Zheng, K.-w.; Zhang, J.-y.; He, Y.-d.; Gong, J.-y.; Wen, C.-j.; Chen, J.-n.; Hao, Y.-h.; Tan, Z.
10.1101/2020.05.06.080622 — biochemistry — Posted on 2020-05-08
3952 Phage recombination drives evolution of spore-forming Bacilli
Dragos, A.; B, P.; Hasan, Z.; Lenz-Strube, M.; Kempen, P. J.; Maroti, G.; Kaspar, C.; Bischofs, I. B.; Kovacs, A. T.
10.1101/2020.05.06.055103 — microbiology — Posted on 2020-05-07
3953 Full-length 16S rRNA gene amplicon analysis of human gut microbiota using MinION™ nanopore sequencing confers species-level resolution
Matsuo, Y.; Komiya, S.; Yasumizu, Y.; Yasuoka, Y.; Mizushima, K.; Takagi, T.; Kryukov, K.; Fukuda, A.; Morimoto, Y.; Naito, Y.; Okada, H.; Bono, H.; Nakagawa, S.; Hirota, K.
10.1101/2020.05.06.078147 — microbiology — Posted on 2020-05-08
3954 Dectin-1 limits central nervous system autoimmunity through a non-canonical pathway
Deerhake, M. E.; Danzaki, K.; Inoue, M.; Cardakli, E. D.; Nonaka, T.; Aggarwal, N.; Barclay, W. E.; Ji, R. R.; Shinohara, M. L.
10.1101/2020.05.06.080481 — immunology — Posted on 2020-05-08
3956 Human serum proteome profoundly overlaps with genetic signatures of disease
Emilsson, V.; Gudmundsdottir, V.; Ilkov, M.; Staley, J. R.; Gudjonsson, A.; Gudmundsson, E. F.; Launer, L. J.; Lindeman, J. H.; Morton, N. M.; Aspelund, T.; Lamb, J. R.; Jennings, L. L.; Gudnason, V.
10.1101/2020.05.06.080440 — genetics — Posted on 2020-05-08
3957 Reclassification of seven honey bee symbiont strains as Bombella apis
Smith, E. A.; Anderson, K. E.; Corby-Harris, V.; McFrederick, Q. S.; Newton, I. L. G.
10.1101/2020.05.06.081802 — microbiology — Posted on 2020-05-08
3958 Recurrent evolution of vertebrate transcription factors by transposase capture.
Cosby, R. L.; Judd, J.; Zhang, R.; Zhong, A.; Garry, N.; Pritham, E. J.; Feschotte, C.
10.1101/2020.05.07.082677 — genomics — Posted on 2020-05-07
3960 Polycistronic gene expression in the model microorganism Ustilago maydis
Muentjes, K.; Philipp, M.; Huesemann, L.; Heucken, N.; Weidtkamp-Peters, S.; Schipper, K.; Zurbriggen, M.; Feldbrugge, M.
10.1101/2020.05.06.081414 — microbiology — Posted on 2020-05-07
3961 Holobiont Urbanism: sampling urban beehives reveals cities' metagenomes
Henaff, E. M.; Najjar, D.; Perez, M.; Flores, R.; Woebken, C.; Mason, C.; Slavin, K.
10.1101/2020.05.07.075093 — microbiology — Posted on 2020-05-07
3963 Uropathogenic E. coli induces DNA damage in the bladder
Chagneau, C. V.; Massip, C.; Bossuet-Greif, N.; Fremez, C.; Motta, J.-P.; Shima, A.; Besson, C.; Le Faouder, P.; Cenac, N.; Roth, M.-P.; Coppin, H.; Fontanie, M.; Martin, P.; Nougayrede, J.-P.; Oswald, E.
10.1101/2020.05.07.080291 — microbiology — Posted on 2020-05-07
3964 Single-cell longitudinal analysis of SARS-CoV-2 infection in human bronchial epithelial cells
Ravindra, N. G.; Alfajaro, M. M.; Gasque, V.; Wei, J.; Filler, R. B.; Huston, N. C.; Wan, H.; Szigeti-Buck, K.; Wang, B.; Montgomery, R. R.; eisenbarth, S. C.; Williams, A.; Pyle, A. M.; Iwasaki, A.; Horvath, T. L.; Foxman, E. F.; van Dijk, D.; Wilen, C.
10.1101/2020.05.06.081695 — microbiology — Posted on 2020-05-07
3965 A Combined approach of MALDI-TOF Mass Spectrometry and multivariate analysis as a potential tool for the detection of SARS-CoV-2 virus in nasopharyngeal swabs.
Rocca, M. F.; Zintgraff, J. C.; Dattero, M. E.; Silva Santos, L.; Ledesma, M.; Vay, C.; Prieto, M. A.; Benedetti, E.; Avaro, M.; Russo, M.; Nachtigall, F. M.; Baumeister, E.
10.1101/2020.05.07.082925 — microbiology — Posted on 2020-05-07
3966 Identifying the effect of vancomycin on HA-MRSA strains using bacteriological and physiological media
Rajput, A.; Poudel, S.; Tsunemoto, H.; Meehan, M.; Szubin, R.; Olson, C.; Seif, Y.; Lamsa, A.; Dillon, N.; Vrbanac, A.; Sugie, J.; Dahesh, S.; Monk, J.; Dorrestein, P.; Pogliano, J.; Nizet, V.; Feist, A.; Palsson, B. O.
10.1101/2020.05.06.079640 — microbiology — Posted on 2020-05-07
3967 Nanoscale imaging of bacterial infections by sphingolipid expansion microscopy
Goetz, R.; Kunz, T. C.; Fink, J.; Solger, F.; Schlegel, J.; Seibel, J.; Kozjak-Pavlovic, V.; Rudel, T.; Sauer, M.
10.1101/2020.05.06.080663 — microbiology — Posted on 2020-05-07
3970 Taxonomic reassignment of Pseudohaptolina birgeri comb. nov. (Haptophyta)
Ribeiro, C. G.; dos Santos, A. L.; Probert, I.; Vaulot, D.; Edvardsen, B.
10.1101/2020.05.06.081489 — microbiology — Posted on 2020-05-07
3971 Lifestyle adaptations of Rhizobium from rhizosphere to symbiosis
Wheatley, R.; Ford, B.; Li, L.; Aroney, S.; Knights, H.; Ledermann, R.; East, A.; Ramachandran, V.; Poole, P.
10.1101/2020.05.07.082560 — microbiology — Posted on 2020-05-07
3972 Adaptable and Efficient Genome Editing by sgRNA-Cas9 Protein Co-injection into Drosophila
Nyberg, K. G.; Nguyen, J.; Kwon, Y.-J.; Blythe, S. A.; Beitel, G. J.; Carthew, R. W.
10.1101/2020.05.07.080762 — genetics — Posted on 2020-05-07
3974 A simple RNA preparation method for SARS-CoV-2 detection by RT-qPCR
Wozniak, A.; Cerda, A.; Ibarra-Henriquez, C.; Sebastian, V.; Armijo, G.; Lamig, L.; Miranda, C.; Lagos, M.; Solari, S.; Guzman, A. M.; Quiroga, T.; Hitschfeld, S.; Riveras, E.; Ferres, M.; Gutierrez, R. A.; Garcia, P.
10.1101/2020.05.07.083048 — molecular biology — Posted on 2020-05-07
3975 The coding capacity of SARS-CoV-2
Finkel, Y.; Mizrahi, O.; Nachshon, A.; Weingarten-Gabbay, S.; Yahalom-Ronen, Y.; Tamir, H.; Achdout, H.; Melamed, S.; Weiss, S.; Isrealy, T.; Paran, N.; Schwartz, M.; Stern-Ginossar, N.
10.1101/2020.05.07.082909 — microbiology — Posted on 2020-05-07
3976 Neutral sphingomyelinase 2 regulates inflammatory responses in monocytes/macrophages induced by TNF-α
Al-Rashed, F.; Ahmad, Z.; Thomas, R.; Melhem, M.; Snider, A. J.; Obeid, L. M.; Al-Mulla, F.; Hannun, Y. A.; Ahmad, R.
10.1101/2020.05.06.080382 — immunology — Posted on 2020-05-07
3978 COVID-19: Viral-host interactome analyzed by network based-approach model to study pathogenesis of SARS-CoV-2 infection.
Messina, F.; Giombini, E.; Agrati, C.; Vairo, F.; Ascoli Bartoli, T.; Al Moghazi, S.; Piancentini, M.; Locatelli, F.; Kobinger, G.; Maeurer, M.; Zumla, A.; Capobianchi, M. R.; Lauria, F. N.; Ippolito, G.
10.1101/2020.05.07.082487 — bioinformatics — Posted on 2020-05-07
3980 Development of a COVID-19 vaccine based on the receptor binding domain displayed on virus-like particles
Zha, L.; Zhao, H.; Mohsen, M. O.; Hong, L.; Li, Z.; Yao, C.; Chen, H.; Liu, X.; Chang, X.; Zhang, J.; Li, D.; Wu, K.; Vogel, M.; Bachmann, M. F.; Wang, J.
10.1101/2020.05.06.079830 — immunology — Posted on 2020-05-07
3983 Suramin inhibits SARS-CoV-2 infection in cell culture by interfering with early steps of the replication cycle
Salgado-Benvindo, C.; Thaler, M.; Tas, A.; Ogando, N. S.; Bredenbeek, P. J.; Ninaber, D.; Wang, Y.; Hiemstra, P.; Snijder, E. J.; van Hemert, M. J.
10.1101/2020.05.06.081968 — microbiology — Posted on 2020-05-07
3984 Genomic characterisation and context of the blaNDM-1 carbapenemase in Escherichia coli ST101.
Ashcroft, M. M.; Forde, B. M.; Phan, M.-D.; Peters, K. M.; Henderson, A. M.; Hancock, S. J.; Roberts, L. W.; White, R. T.; Chan, K.-G.; Chong, T. M.; Yin, W.-F.; Paterson, D. L.; Walsh, T. R.; Schembri, M. A.; Beatson, S. A.
10.1101/860726 — genomics — Posted on 2020-05-07
3988 Establishment of a stable zg6pdM118-144 transgenic zebrafish model of glucose-6-phosphate dehydrogenase deficiency
Xia, H.-X.; Zhou, Y.-H.; Tuo, Y.-Y.; Ren, P.-P.; Song, J.; Shang, L.-J.; Jin, J.; He, Z.-X.; Shu, L.
10.1101/2020.04.28.066779 — zoology — Posted on 2020-05-07
3991 A mouse-adapted SARS-CoV-2 model for the evaluation of COVID-19 medical countermeasures
Dinnon, K. H.; Leist, S. R.; Schafer, A.; Edwards, C. E.; Martinez, D. R.; Montgomery, S. A.; West, A.; Yount, B. L.; Hou, Y. J.; Adams, L. E.; Gully, K. L.; Brown, A. J.; Huang, E.; Bryant, M. D.; Choong, I. C.; Glenn, J. S.; Gralinski, L. E.; Sheahan, T. P.; Baric, R. S.
10.1101/2020.05.06.081497 — microbiology — Posted on 2020-05-07
3993 Caspases from Scleractinian Coral Show Unique Regulatory Features
Shrestha, S.; Tung, J.; Grinshpon, R. D.; Swartz, P. D.; Hamilton, P. T.; Dimos, B.; Mydlarz, L.; Clark, C.
10.1101/2020.04.13.039685 — biochemistry — Posted on 2020-05-07
3996 A Proteogenomic workflow reveals distinct molecular phenotypes related to breast cancer appearance
De Marchi, T.; Pyl, P. T.; Sjöstrom, M.; Klasson, S.; Sartor, H.; Malmström, J. A.; Malmström, L.; Nimeus, E.
10.1101/2020.05.05.077974 — systems biology — Posted on 2020-05-07
3997 Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer's disease
Rayaprolu, S.; Gao, T.; Xiao, H.; Ramesha, S.; Weinstock, L. D.; Shah, J.; Duong, D.; Dammer, E. B.; Webster, J. A.; Lah, J. J.; Wood, L. B.; Betarbet, R.; Levey, A. I.; Seyfried, N. T.; Rangaraju, S.
10.1101/802694 — neuroscience — Posted on 2020-05-07
3998 Optimal protocols for sequence-based characterization of the human vaginal microbiome
Hugerth, L. W.; Pereira, M.; Zha, Y.; Seifert, M.; Kaldhusdal, V.; Boulund, F.; Krog, M. C.; Bashir, Z.; Hamsten, M.; Fransson, E.; Svarre-Nielsen, H.; Schuppe-Koistinen, I.; Engstrand, L.
10.1101/2020.05.05.079996 — molecular biology — Posted on 2020-05-07
3999 Dynamics of T cell activation mediated by eIF3 interactions with T cell receptor mRNAs
De Silva, D.; Ferguson, L.; Smith, B. E.; Chin, G. H.; Apathy, R. A.; Roth, T. L.; Kudla, M.; Marson, A.; Ingolia, N. T.; Cate, J. H. D.
10.1101/2019.12.20.885558 — molecular biology — Posted on 2020-05-07
4001 Activation of oral epithelial EphA2-EFGR signaling by Candida albicans virulence factors
Swidergall, M.; Solis, N. V.; Millet, N.; Huang, M. Y.; Lin, J.; Phan, Q.; Lazarus, M. D.; Wang, Z.; Mitchell, A. P.; Filler, S. G.
10.1101/491076 — microbiology — Posted on 2020-05-07
4003 Accelerated loss of hypoxia response in zebrafish with familial Alzheimer's disease-like mutation of Presenilin 1.
Newman, M.; Moussavi Nik, H.; Sutherland, G.; Hin, N.; Kim, W.; Halliday, G.; Jayadev, S.; Smith, C.; Laird, A.; Lucas, C.; Kittipassorn, T.; Peet, D.; Lardelli, M.
10.1101/526277 — genomics — Posted on 2020-05-07
4004 A near-chromosome level genome assembly of Anopheles stephensi
Chida, A. R.; Ravi, S.; Jayaprasad, S.; Paul, K.; Saha, J.; Suresh, C.; Whadgar, S.; Kumar, N.; Rao K, R.; Ghosh, C.; Choudhary, B.; Subramani, S.; Srinivasan, S.
10.1101/2020.04.27.063040 — genomics — Posted on 2020-05-07
4005 Fused in sarcoma regulates DNA replication timing and progression
Jia, W.; Scalf, M. A.; Tonzi, P.; Millikin, R. J.; Kim, S. H.; Guns, W. M.; Liu, L.; Mastrocola, A. S.; Smith, L. M.; Huang, T. T.; Tibbetts, R. S.
10.1101/2020.04.22.055343 — genomics — Posted on 2020-05-07
4006 Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation
Ren, W.; Fan, H.; Grimm, S. A.; Guo, Y.; Kim, J. J.; Li, L.; Petell, C. J.; Tan, X.-F.; Zhang, Z.-M.; Coan, J. P.; Yin, J.; Gao, L.; Cai, L.; Detrick, B.; Cetin, B.; Wang, Y.; Cui, Q.; Strahl, B. D.; Gozani, O.; Miller, K. M.; O'Leary, S. E.; Wade, P. A.; Patel, D. J.; Wang, G. G.; Song, J.
10.1101/2020.04.27.064493 — genetics — Posted on 2020-05-07
4009 Regulation of blood cell transdifferentiation by oxygen sensing neurons in Drosophila
Corcoran, S.; Mase, A.; Hashmi, Y.; Ouyang, D.; Augsburger, J.; Jacobs, T.; Kukar, K.; Brueckner, K.
10.1101/2020.04.22.056622 — developmental biology — Posted on 2020-05-07
4010 Pattern recognition receptors confer plant salt tolerance via WRKY18/WRKY40 transcription factors
Loo, E. P.; Tajima, Y.; Yamada, K.; Hirase, T.; Ariga, H.; Fujiwara, T.; Tanaka, K.; Taji, T.; Somssich, I. E.; Parker, J. E.; Saijo, Y.
10.1101/2020.05.07.082172 — plant biology — Posted on 2020-05-07
4012 Neural activity during a simple reaching task in macaques is counter to theories of basal ganglia-thalamic communication
Schwab, B. C.; Kase, D.; Zimnik, A.; Rosenbaum, R.; Codianni, M. G.; Rubin, J. E.; Turner, R. S.
10.1101/546598 — neuroscience — Posted on 2020-05-07
4014 Whole-genome sequencing of a sporadic primary immunodeficiency cohort
Thaventhiran, J. E. D.; Lango Allen, H.; Burren, O. S.; Rae, W.; Greene, D.; Staples, E.; Zhang, Z.; Farmery, J. H. R.; Simeoni, I.; Maimaris, J.; Penkett, C.; Stephens, J.; Deevi, S. V. V.; Sanchis-Juan, A.; Gleadall, N. S.; Thomas, M. J.; Sargur, R. B.; Gordins, P.; Baxendale, H. E.; Brown, M.; Tuijnenburg, P.; Worth, A.; Hanson, S.; Linger, R.; Buckland, M. S.; Rayner-Matthews, P. J.; Gilmour, K. C.; Samarghitean, C.; Seneviratne, S. L.; Lyons, P. A.; Sansom, D. M.; Lynch, A. G.; Megy, K.; Ellinghaus, E.; Ellinghaus, D.; Jorgensen, S. F.; Karlsen, T. H.; Stirrups, K. E.; Cutler, A. J.; Kuma
10.1101/499988 — immunology — Posted on 2020-05-07
4017 Identification of 370 loci for age at onset of sexual and reproductive behaviour, highlighting common aetiology with reproductive biology, externalizing behaviour and longevity
Mills, M. C.; Tropf, F. C.; Brazel, D. M.; van Zuydam, N.; Vaez, A.; eQTLGen Consortium, ; BIOS Consortium, ; Pers, T. H.; Snieder, H.; Perry, J. R. B.; Ong, K. K.; den Hoed, M.; Barban, N.; Day, F. R.; Human Reproductive Behaviour Consortium,
10.1101/2020.05.06.081273 — genetics — Posted on 2020-05-07
4020 Transcriptional comparison of Testicular Adrenal Rest Tumors with fetal and adult tissues
Schröder, M. A. M.; Sweep, F. C. G. J.; van Herwaarden, A. E.; Rowan, A. E.; Korbie, D.; Mitchell, R. T.; Stikkelbroeck, N. M. M. L.; Claahsen-van der Grinten, H. L.; Span, P. N.
10.1101/2020.05.07.082313 — molecular biology — Posted on 2020-05-07
4022 Prokaryotic Argonaute from Archaeoglobus fulgidus interacts with DNA as a homodimer
Golovinas, E.; Rutkauskas, D.; Manakova, E.; Jankunec, M.; Silanskas, A.; Sasnauskas, G.; Zaremba, M.
10.1101/2020.05.06.080267 — biochemistry — Posted on 2020-05-07
4025 Determinants of Predictability in Multi-decadal Forest Community and Carbon Dynamics
Raiho, A. M.; Dietze, M.; Dawson, A.; Rollinson, C.; Tipton, J.; McLachlan, J.
10.1101/2020.05.05.079871 — ecology — Posted on 2020-05-07
4027 Mycena genomes resolve the evolution of fungal bioluminescence
Ke, H.-M.; Lee, H.-H.; Lin, C.-Y. I.; Liu, Y.-C.; Lu, M. R.; Hsieh, J.-W. A.; Chang, C.-C.; Wu, P.-H.; Lu, M. J.; Li, J.-Y.; Shang, G.; Lu, R. J.-H.; Nagy, L. G.; Chen, P.-Y.; Kao, H.-W.; Tsai, I. J.
10.1101/2020.05.06.079921 — genomics — Posted on 2020-05-07
4028 MEIS-WNT5A axis regulates development of 4th ventricle choroid plexus
Kaiser, K.; Jang, A.; Lun, M.; Prochazka, J.; Machon, O.; Prochazkova, M.; Laurent, B.; Gyllborg, D.; van Amerongen, R.; Kompanikova, P.; Wu, F.; Barker, R. A.; Uramova, I.; Sedlacek, R.; Kozmik, Z.; Arenas, E.; Lehtinen, M. K.; Bryja, V.
10.1101/2020.05.07.082370 — developmental biology — Posted on 2020-05-07
4035 Cortical Thickness Trajectories across the Lifespan: Data from 17,075 healthy individuals aged 3-90 years
Frangou, S.; Modabbernia, A.; Doucet, G. E.; Papachristou, E.; Williams, S. C.; Agartz, I.; Aghajani, M.; Akudjedu, T. N.; Albajes-Eizagirre, A.; Alnaes, D.; Alpert, K. I.; Andersson, M.; Andreasen, N.; Andreassen, O. A.; Asherson, P.; Banaschewski, T.; Bargallo, N.; Baumeister, S.; Baur-Streubel, R.; Bertolino, A.; Bonvino, A.; Boomsma, D. I.; Borgwardt, S.; Bourque, J.; Brandeis, D.; Breier, A.; Brodaty, H.; Brouwer, R. M.; Buitelaar, J. K.; Busatto, G. F.; Buckner, R. L.; Calhoun, V.; Canales-Rodriguez, E. J.; Cannon, D. M.; Caseras, X.; Castellanos, F. X.; Cervenka, S.; Chaim-Avancini, T.
10.1101/2020.05.05.077834 — neuroscience — Posted on 2020-05-07
4037 Efficient Bayesian inference of phylogenetic trees from large scale, low-depth genome-wide single-cell data
Dorri, F.; Salehi, S.; Chern, K.; Funnell, T.; Williams, M.; Lai, D.; Andronescu, M.; Campbell, K. R.; McPherson, A.; Aparicio, S.; Roth, A.; Shah, S. P.; Bouchard-Cote, A.
10.1101/2020.05.06.058180 — bioinformatics — Posted on 2020-05-07
4039 In situ detection of protein interactions for recombinant therapeutic enzymes
Samoudi, M.; Kuo, C.-C.; Robinson, C. M.; Shams-Ud-Doha, K.; Schinn, S.-M.; Kol, S.; Weiss, L.; Petersen Bjorn, S.; Voldborg, B. G.; Rosa Campos, A.; Lewis, N. E.
10.1101/2020.05.06.081885 — synthetic biology — Posted on 2020-05-07
4042 Integrative Single-cell RNA-Seq and ATAC-Seq Analysis of Human Foetal Liver and Bone Marrow Haematopoiesis
Ranzoni, A. M.; Tangherloni, A.; Berest, I.; Riva, S. G.; Myers, B.; Strzelecka, P. M.; Xu, J.; Panada, E.; Mohorianu, I.; Zaugg, J. B.; Cvejic, A.
10.1101/2020.05.06.080259 — cell biology — Posted on 2020-05-07
4044 Mutational processes impact the evolution of anti-EGFR antibody resistance in colorectal cancer
Woolston, A.; Barber, L. J.; Griffiths, B.; Matthews, N.; Rao, S.; Watkins, D.; Chau, I.; Starling, N.; Cunningham, D.; Gerlinger, M.
10.1101/2020.05.07.082339 — cancer biology — Posted on 2020-05-07
4046 Identification of PDE6D as a potential target of sorafenib via PROTAC technology
Li, Y.; Meng, Q.; Wang, P.; Liu, X.; Fu, Q.; Xie, Y.; Zhou, Y.; Qi, X.; Huang, N.
10.1101/2020.05.06.079947 — biochemistry — Posted on 2020-05-07
4048 Subcortical Volume Trajectories across the Lifespan: Data from 18,605 healthy individuals aged 3-90 years
Dima, D.; Papachristou, E.; Modabbernia, A.; Doucet, G. E.; Agartz, I.; Aghajani, M.; Akudjedu, T. N.; Albajes-Eizagirre, A.; Alnaes, D.; Alpert, K. I.; Andersson, M.; Andreasen, N.; Andreassen, O. A.; Asherson, P.; Banaschewski, T.; Bargallo, N.; Baumeister, S.; Baur-Streubel, R.; Bertolino, A.; Bonvino, A.; Boomsma, D. I.; Borgwardt, S.; Bourque, J.; Brandeis, D.; Breier, A.; Brodaty, H.; Brouwer, R. M.; Buitelaar, J. K.; Busatto, G. F.; Buckner, R. L.; Calhoun, V.; Canales-Rodriguez, E. J.; Cannon, D. M.; Caseras, X.; Castellanos, F. X.; Cervenka, S.; Chaim-Avancini, T. M.; Ching, C. R.; Cl
10.1101/2020.05.05.079475 — neuroscience — Posted on 2020-05-07
4049 Multifocal small intestine neuroendocrine tumors form by independent somatic evolution
Elias, E.; Ardalan, A.; Lindberg, M.; Reinsbach, S.; Muth, A.; Nilsson, O.; Arvidsson, Y.; Larsson, E.
10.1101/2020.05.06.080499 — genomics — Posted on 2020-05-07
4053 Chromatin profiling reveals reorganization of lysine specific demethylase 1 by an oncogenic fusion protein
Theisen, E. R.; Selich-Anderson, J.; Miller, K. R.; Tanner, J. M.; Taslim, C.; Pishas, K. I.; Sharma, S.; Lessnick, S. L.
10.1101/2020.05.05.079533 — cancer biology — Posted on 2020-05-07
4056 Eyes are essential for magnetoreception in a mammal
Caspar, K. R.; Moldenhauer, K.; Moritz, R. E.; Malkemper, E. P.; Begall, S.
10.1101/2020.05.07.082388 — animal behavior and cognition — Posted on 2020-05-07
4057 Cutting out the middle clam: lucinid endosymbiotic bacteria are also associated with seagrass roots worldwide
Martin, B. C.; Middleton, J. A.; Fraser, M. W.; Marshall, I. P. G.; Scholz, V. V.; Schmidt, H.
10.1101/2020.05.06.080127 — plant biology — Posted on 2020-05-07
4058 A recombineering pipeline to clone large and complex genes in Chlamydomonas
Emrich-Mills, T.; Yates, G.; Barrett, J.; Grouneva, I.; Lau, C. S.; Walker, C. E.; Kwok, T. K.; Davey, J. W.; Johnson, M. P.; Mackinder, L.
10.1101/2020.05.06.080416 — plant biology — Posted on 2020-05-07
4059 Teacher-student neural coupling during teaching and learning
Nguyen, M.; Chang, A.; Micciche, E.; Meshulam, M.; Nastase, S. A.; Hasson, U.
10.1101/2020.05.07.082958 — neuroscience — Posted on 2020-05-07
4060 Prefrontal neural dynamics for behavioral decisions and attentional control
Erez, Y.; Kadohisa, M.; Petrov, P.; Sigala, N.; Buckley, M. J.; Kusunoki, M.; Duncan, J.
10.1101/2020.05.06.080325 — neuroscience — Posted on 2020-05-07
4061 RAN translation of the expanded CAG repeats in the SCA3 disease context
Jazurek-Ciesiolka, M.; Ciesiolka, A.; Komur, A. A.; Urbanek-Trzeciak, M. O.; Fiszer, A.
10.1101/2020.05.07.082354 — molecular biology — Posted on 2020-05-07
4062 Intrinsic defects in lymph node stromal cells underpin poor germinal center responses during aging
Denton, A. E.; Silva-Cayetano, A.; Dooley, J.; Hill, D. L.; Carr, E. J.; Robert, P.; Meyer-Hermann, M.; Liston, A.; Linterman, M. A.
10.1101/2020.05.07.082255 — immunology — Posted on 2020-05-07
4063 The use of two-sample methods for Mendelian randomization analyses on single large datasets
Minelli, C.; Del Greco M., F.; van der Plaat, D. A.; Bowden, J.; Sheehan, N. A.; Thompson, J.
10.1101/2020.05.07.082206 — genetics — Posted on 2020-05-07
4066 A Method to sort heterogenous cell populations based on migration in 2D and 3D environments
Arora, A.; Galeano, J. L.; Myaing, M. Z.; Arasi, B.; Huang, R. Y.-J.; DasGupta, R.; Biro, M.; Viasnoff, V.
10.1101/2020.05.06.080234 — cell biology — Posted on 2020-05-07
4073 Small molecule enhancers of endosome-to-cytosol import augment anti-tumour immunity
Kozik, P.; Gros, M.; Itzhak, D. N.; Joannas, L.; Magalhaes, J. G.; Alloatti, A.; Del Nery, E.; Borner, G. H.; Amigorena, S.
10.1101/2020.05.05.079491 — immunology — Posted on 2020-05-07
4074 Comprehensive mapping of the human cytokine gene regulatory network
Santoso, C.; Li, Z.; Lal, S.; Yuan, S.; Gan, K. A.; Agosto, L.; Liu, X.; Carrasco Pro, S.; Sewell, J.; Henderson, A.; Atianand, M.; Fuxman Bass, J. I.
10.1101/2020.05.05.079657 — immunology — Posted on 2020-05-07
4075 Rare variant enriched identity-by-descent enables the detection of distant relatedness and older divergence between populations
Shetty, A. C.; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, ; TOPMed Population Genetics Working Group, ; O'Connell, J.; Mitchell, B. D.; O'Connor, T. D.
10.1101/2020.05.05.079541 — genomics — Posted on 2020-05-07
4076 Genetic and environmental determinants of variation in the plasma lipidome of older Australian twins
Wong, M. W. K.; Thalamuthu, A.; Braidy, N.; Mather, K. A.; Liu, Y.; Ciobanu, L.; Baune, B. T.; Armstrong, N. J.; Kwok, J.; Schofield, P. R.; Wright, M. J.; Ames, D.; Pickford, R.; Lee, T.; Poljak, A.; Sachdev, P. S.
10.1101/2020.05.05.075606 — genetics — Posted on 2020-05-07
4080 Microglial phagocytosis dysfunction is related to local neuronal activity in a genetic model of epilepsy
Sierra-Torre, V.; Plaza-Zabala, A.; Bonifazi, P.; Abiega, O.; Diaz-Aparicio, I.; Tegelberg, S.; Lehesjoki, A.-E.; Valero, J.; Sierra, A.
10.1101/2020.05.06.075903 — neuroscience — Posted on 2020-05-07
4081 Somatostatin-positive neurons in the reticular thalamus modulate gamma rhythms and visual information in mouse V1
Hoseini, M. S.; Higashikubo, B.; Cho, F. S.; Chang, A. H.; Clemente-Perez, A.; Lew, I.; Stryker, M. P.; Paz, J. T.
10.1101/2020.05.06.081877 — neuroscience — Posted on 2020-05-07
4082 1-Methylnicotinamide is an immune regulatory metabolite in human ovarian cancer
Kilgour, M. K.; MacPherson, S.; Zacharias, L.; Keyes, S.; Pauly, B.; Allard, B.; Smazynski, J.; Watson, P. H.; Stagg, J.; Nelson, B. H.; DeBerardinis, R. J.; Hamilton, P. T.; Lum, J. J.
10.1101/2020.05.05.077990 — immunology — Posted on 2020-05-07
4083 Immunodietica: interrogating the role of diet in autoimmune disease
Gershteyn, I. M.; Burov, A. A.; Miao, B. Y.; Morais, V. H.; Ferreira, L. M. R.
10.1101/2020.05.05.079418 — immunology — Posted on 2020-05-07
4087 Microbe-dependent heterosis in maize
Wagner, M. R.; Tang, C.; Salvato, F.; Clouse, K. M.; Bartlett, A.; Sermons, S.; Hoffmann, M.; Balint-Kurti, P. J.; Kleiner, M.
10.1101/2020.05.05.078766 — plant biology — Posted on 2020-05-07
4088 Evidence for a behaviourally measurable perseverance trait
Maattanen, I.; Makkonen, E.; Jokela, M.; Narvainen, J.; Valiaho, J.; Seppala, V.; Kylmala, J.; Henttonen, P.
10.1101/2020.05.05.079509 — physiology — Posted on 2020-05-07
4091 Conserved long-range RNA structures associated with pre-mRNA processing of human protein-coding genes
Kalmykova, S.; Kalinina, M.; Denisov, S.; Mironov, A.; Skvortsov, D.; Guigo, R.; Pervouchine, D. D.
10.1101/2020.05.05.076927 — bioinformatics — Posted on 2020-05-07
4093 Three-dimensional reconstructions of the internal structures of haustoria in parasitic Orobanchaceae
Masumoto, N.; Suzuki, Y.; Cui, S.; Wakazaki, M.; Sato, M.; Kumaishi, K.; Shibata, A.; Furuta, K. M.; Ichihashi, Y.; Shirasu, K.; Toyooka, K.; Sato, Y.; Yoshida, S.
10.1101/2020.05.07.083055 — plant biology — Posted on 2020-05-07
4094 Validity of the Lumen(R) hand-held metabolic device to measure fuel utilization in healthy young adults
Lorenz, K. A.; Yeshurun, S.; Aziz, R.; Ortiz-Delatorre, J.; Bagley, J. R.; Mor, M.; Kern, M.
10.1101/2020.05.05.078980 — physiology — Posted on 2020-05-07
4101 A 6.5kb intergenic structural variation enhances P450-mediated resistance to pyrethroids in malaria vectors lowering bed net efficacy
Leon, M. M. J.; Benjamin, M. D.; Magellan, T.; Murielle, W. J.; Helen, I.; Micareme, T.; Jack, H.; Gareth, W. D.; Jacob, R. M.; Fidelis, C.-N.; Charles, W. S.
10.1101/2020.05.05.078600 — evolutionary biology — Posted on 2020-05-07
4105 RNA and DNA G-quadruplexes bind to human Dicer and inhibit its activity
Koralewska, N.; Szczepanska, A.; Ciechanowska, K.; Wojnicka, M.; Pokornowska, M.; Milewski, M. C.; Gudanis, D.; Baranowski, D.; Nithin, C.; Bujnicki, J. M.; Gdaniec, Z.; Figlerowicz, M.; Kurzynska-Kokorniak, A.
10.1101/2020.05.05.078592 — biochemistry — Posted on 2020-05-07
4109 Deletion of porcine BOLL causes defective acrosomes and subfertility in Yorkshire boars
Noskova, A.; Wurmser, C.; Crysnanto, D.; Sironen, A.; Uimari, P.; Fries, R.; Andersson, M.; Pausch, H.
10.1101/2020.05.05.074724 — genomics — Posted on 2020-05-07
4110 Repeated genomic signatures of adaptation to urbanisation in a songbird across Europe
Salmon, P.; Jacobs, A.; Ahren, D.; Biard, C.; Dingemanse, N.; Dominoni, D.; Helm, B.; Lundberg, M.; Senar, J. C.; Sprau, P.; Visser, M. E.; Isaksson, C.
10.1101/2020.05.05.078568 — evolutionary biology — Posted on 2020-05-07
4112 Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions
Krainer, G.; Welsh, T. J.; Joseph, J. A.; Espinosa, J. R.; de Csillery, E.; Sridhar, A.; Toprakcioglu, Z.; Gudiskyte, G.; Czekalska, M. A.; Arter, W. E.; St George-Hyslop, P.; Collepardo-Guevara, R.; Alberti, S.; Knowles, T. P.
10.1101/2020.05.04.076299 — biophysics — Posted on 2020-05-07
4113 Cadherin-13 is a critical regulator of GABAergic modulation in human stem cell derived neuronal networks
Mossink, B.; van Rhijn, J.-R.; Wang, S.; van Hugte, E.; Linda, K.; Bak, J.; Verboven, A. H.; Selten, M.; Anania, A.; Jansen, S.; Keller, J. M.; Klein Gunnewiek, T.; Schoenmaker, C.; Oudakker, A.; Frega, M.; van Bokhoven, H.; Schubert, D.; Nadif Kasri, N.
10.1101/2020.05.07.082453 — neuroscience — Posted on 2020-05-07
4114 Myosin 10 and a Cytoneme-Localized Ligand Complex Promote Morphogen Transport
Hall, E. T.; Stewart, D. P.; Dillard, M.; Wagner, B.; Temirov, J.; Cheney, R. E.; Mori, M.; Robinson, C. G.; Ogden, S. K.
10.1101/2020.05.06.080820 — cell biology — Posted on 2020-05-07
4117 Lack of astrocytic glycogen alters synaptic plasticity but not seizure susceptibility
Duran, J.; Brewer, M. K.; Hervera, A.; Gruart, A.; del Rio, J. A.; Delgado-Garcia, J. M.; Guinovart, J. J.
10.1101/2020.05.06.080978 — biochemistry — Posted on 2020-05-07
4120 Establishment and maintenance of motor neuron identity via temporal modularity in terminal selector function
Li, Y.; Osuma, A.; Correa, E.; Okebalama, M.; Dao, P.; Gaylord, O.; Aburas, J.; Islam, P.; Brown, A. E. X.; Kratsios, P.
10.1101/2020.05.06.080184 — developmental biology — Posted on 2020-05-07
4121 Splicing variation of BMP2K balances endocytosis, COPII trafficking and autophagy in erythroid cells
Cendrowski, J.; Kaczmarek, M.; Kuzmicz-Kowalska, K.; Mazur, M.; Jastrzebski, K.; Brewinska-Olchowik, M.; Kominek, A.; Piwocka, K.; Miaczynska, M.
10.1101/2020.05.05.079970 — cell biology — Posted on 2020-05-07
4122 Metabolomic and Proteomic Stratification of Equine Osteoarthritis
Anderson, J. R.; Phelan, M. M.; Caamano-Gutierrez, E.; Clegg, P. D.; Rubio-Martinez, L. M.; Peffers, M. J.
10.1101/2020.05.04.077305 — molecular biology — Posted on 2020-05-07
4123 Linking phenotype, genotype and ecology: antimicrobial resistance in the zoonotic pathogen Streptococcus suis
Hadjirin, N. F.; Miller, E. L.; Murray, G. G. R.; Yen, P. L. K.; Phuc, H. D.; Wileman, T. M.; Hernandez-Garcia, J.; Williamson, S. M.; Parkhill, J.; Maskell, D. J.; Zhou, R.; Fittipaldi, N.; Gottschalk, M.; Tucker, A. .W.; Hoa, N. T.; Welch, J. J.; Weinert, L. A.
10.1101/2020.05.05.078493 — microbiology — Posted on 2020-05-07
4124 Systematic protein complex profiling and differential analysis from co-fractionation mass spectrometry data
Fossati, A.; Li, C.; Sykacek, P.; Heusel, M.; Frommelt, F.; Uliana, F.; Hallal, M.; Bludau, I.; Klemens, C. T.; Xue, P.; Purcell, A. W.; Gstaiger, M.; Aebersold, R.
10.1101/2020.05.06.080465 — systems biology — Posted on 2020-05-07
4127 Lack of Kcnn4 improves mucociliary clearance in muco-obstructive lung disease.
Vega, G.; Guequen, A.; Philp, A. R.; Gianotti, A.; Arzola, L.; Villalon, M.; Zegarra-Moran, O.; Galietta, L. J.; Mall, M. A.; Flores, C. A.
10.1101/2020.05.06.079707 — physiology — Posted on 2020-05-07
4128 Using structural connectivity to augment community structure in EEG functional connectivity
Glomb, K.; Mullier, E.; Carboni, M.; Rubega, M.; Iannotti, G.; Tourbier, S.; Seeber, M.; Vulliemoz, S.; Hagmann, P.
10.1101/831743 — neuroscience — Posted on 2020-05-07
4130 Roles of developmentally regulated KIF2A alternative isoforms in cortical neuron migration and differentiation
Akkaya, C.; Atak, D.; Kamacioglu, A.; Akarlar, B. A.; Guner, G.; Bayam, E.; Taskin, A. C.; Ozlu, N.; Ince Dunn, G.
10.1101/2020.05.07.081216 — developmental biology — Posted on 2020-05-07
4131 IN VITRO RECONSTITUTION OF DYNEIN FORCE EXERTION IN BULK CYTOPLASM
Palenzuela, H.; Lacroix, B.; Salle, J.; Minami, K.; Shima, T.; Jegou, A.; Romet-Lemonne, G.; Minc, N.
10.1101/2020.05.06.081364 — biophysics — Posted on 2020-05-07
4133 Erosion of human X chromosome inactivation causes major remodelling of the iPSC proteome
Brenes, A. J.; Yoshikawa, H.; Bensaddek, D.; Mirauta, B.; Seaton, D. D.; Hukelmann, J. L.; Jiang, H.; Stegle, O.; Lamond, A. I.
10.1101/2020.03.18.997049 — molecular biology — Posted on 2020-05-07
4139 A neural code for egocentric spatial maps in the human medial temporal lobe
Kunz, L.; Brandt, A.; Reinacher, P. C.; Staresina, B. P.; Reifenstein, E. T.; Weidemann, C. T.; Herweg, N. A.; Tsitsiklis, M.; Kempter, R.; Kahana, M. J.; Schulze-Bonhage, A.; Jacobs, J.
10.1101/2020.03.03.973131 — neuroscience — Posted on 2020-05-07
4140 The WD and linker domains of ATG16L1 required for non canonical autophagy limit lethal influenza A virus infection at epithelial surfaces.
Wang, Y.; Zhang, W.; Jefferson, M.; Sharma, P.; Bone, B.; Kipar, A.; Coombes, J. L.; Pearson, T.; Mann, A.; Zhekova, A.; Bao, Y.; Tripp, R. A.; Yamauchi, Y.; Carding, S. R.; Mayer, U.; Powell, P. P.; Stewart, J. P.; Wileman, T.
10.1101/2020.01.15.907873 — microbiology — Posted on 2020-05-07
4141 A comprehensive benchmarking of WGS-based structural variant callers
Sarwal, V.; Niehus, S.; Ayyala, R.; Chang, S.; Lu, A.; Darci-Maher, N.; Littman, R.; Wesel, E.; Castellanos, J.; Chikka, R.; Distler, M. G.; Eskin, E.; Flint, J.; Mangul, S.
10.1101/2020.04.16.045120 — bioinformatics — Posted on 2020-05-07
4153 MARCH8 inhibits viral infection by two different mechanisms
Zhang, Y.; Tada, T.; Ozono, S.; Kishigami, S.; Fujita, H.; Tokunaga, K.
10.1101/2020.04.09.035204 — microbiology — Posted on 2020-05-07
4154 Analysis of Plasmodium vivax schizont transcriptomes from field isolates reveals heterogeneity of expression of genes involved in host-parasite interactions
Siegel, S. V.; Chappell, L.; Hostetler, J. B.; Amaratunga, C.; Suon, S.; Bohme, U.; Berriman, M.; Fairhurst, R. M.; Rayner, J. C.
10.1101/2020.03.20.998294 — genomics — Posted on 2020-05-07
4155 A novel framework for characterizing genomic haplotype diversity in the human immunoglobulin heavy chain locus
Rodriguez, O. L.; Gibson, W. S.; Parks, T.; Emery, M.; Powell, J.; Strahl, M.; Deikus, G.; Auckland, K.; Eichler, E. E.; Marasco, W. A.; Sebra, R.; Sharp, A. J.; Smith, M. L.; Bashir, A.; Watson, C. T.
10.1101/2020.04.19.049270 — genomics — Posted on 2020-05-07
4157 Spatial inter-centromeric interactions facilitated the emergence of evolutionary new centromeres
Guin, K.; Chen, Y.; Mishra, R.; Muzaki, S. R. B. M.; Thimmappa, B. C.; O'Brien, C. E.; Butler, G.; Sanyal, A.; Sanyal, K.
10.1101/2020.02.07.938175 — genetics — Posted on 2020-05-07
4158 Combining metabarcoding and morphological approaches to identify phytoplankton taxa associated with harmful algal blooms
Esenkulova, S.; Sutherland, B. J. G.; Tabata, A.; Haigh, N.; Pearce, C. M.; Miller, K. M.
10.1101/816926 — genetics — Posted on 2020-05-07
4159 Structural genomic variation leads to unexpected genetic differentiation in Lake Tanganyika's sardines
Junker, J.; Rick, J. A.; McIntyre, P. B.; Kimirei, I.; Sweke, E. A.; Mosille, J. B.; Wehrli, B.; Dinkel, C.; Mwaiko, S.; Seehausen, O.; Wagner, C. E.
10.1101/800904 — evolutionary biology — Posted on 2020-05-07
4163 A Modular Framework for Multiscale Spatial Modeling of Viral Infection and Immune Response in Epithelial Tissue
Sego, T. J.; Aponte-Serrano, J. O.; Ferrari Gianlupi, J.; Heaps, S.; Breithaupt, K.; Brusch, L.; Osborne, J. M.; Quardokus, E. M.; Glazier, J. A.
10.1101/2020.04.27.064139 — bioengineering — Posted on 2020-05-07
4166 Remote control of CAR T cell therapies by thermal targeting
Miller, I. C.; Sun, L.-K.; Harris, A. M.; Gamboa, L.; Zamat, A.; Kwong, G. A.
10.1101/2020.04.26.062703 — bioengineering — Posted on 2020-05-07
4167 Measuring Sequences of Representations with Temporally Delayed Linear Modelling
Liu, Y.; Dolan, R.; Penagos-Vargas, H. L.; Kurth-Nelson, Z.; Behrens, T. E. J.
10.1101/2020.04.30.066407 — neuroscience — Posted on 2020-05-07
4168 Integrated requirement of non-specific and sequence-specific DNA binding in MYC-driven transcription
Pellanda, P.; Dalsass, M.; Filipuzzi, M.; Loffreda, A.; Verrecchia, A.; Castillo Cano, V.; Doni, M.; Morelli, M. J.; Beaulieu, M.-E.; Soucek, L.; Mazza, D.; Mapelli, M.; Kress, T.; Amati, B.; Sabo, A.
10.1101/2020.05.04.076190 — molecular biology — Posted on 2020-05-07
4170 On a reef far, far away: Offshore transport of floodwaters following extreme storms impacts sponge health and associated microbial communities
Shore, A.; Sims, J. A.; Grimes, M.; Howe-Kerr, L. I.; Stadler, L.; Sylvan, J. B.; Shamberger, K. E.; Davies, S. W.; Santiago-Vasquez, L. Z.; Correa, A. M.
10.1101/2020.04.27.064568 — microbiology — Posted on 2020-05-07
4171 An association between the gut microbiota and immune cell dynamics in humans.
Schluter, J.; Peled, J. U.; Taylor, B. P.; Smith, M.; Markey, K. A.; Taur, Y.; Niehus, R.; Staffas, A.; Dai, A.; Fontana, E.; Amoretti, L. A.; Wright, R. J.; Morjaria, S.; Fenelus, M.; Pessin, M. S.; Chao, N. J.; Lew, M.; Bohannon, L.; Bush, A.; Sung, A. D.; Hohl, T. M.; Perales, M.-A.; van den Brink, M. R. M.; Xavier, J. B.
10.1101/618256 — microbiology — Posted on 2020-05-07
4174 Task-generic and task-specific connectivity modulations in the ADHD brain: An integrated analysis across multiple tasks
Chauvin, R. J.; Buitelaar, J. K.; Sprooten, E.; Oldehinkel, M.; Franke, B.; Hartman, C.; Heslenfeld, D. J.; Hoekstra, P. J.; Oosterlaan, J.; Beckmann, C. F.; Mennes, M.
10.1101/755603 — neuroscience — Posted on 2020-05-07
4175 Serotonergic modulation of visual neurons in Drosophila melanogaster
Myers Gschweng, K. M.; Sampson, M. M.; Hardcastle, B. J.; Bonanno, S. L.; Sizemore, T. R.; Arnold, R. C.; Gao, F.; Dacks, A. M.; Frye, M. A.; Krantz, D. E.
10.1101/619759 — neuroscience — Posted on 2020-05-07
4178 Darwinian properties and their trade-offs in autocatalytic RNA reaction networks
Ameta, S.; Arsene, S.; Foulon, S.; Saudemont, B.; Clifton, B. E.; Griffiths, A. D.; Nghe, P.
10.1101/726497 — evolutionary biology — Posted on 2020-05-07
4179 Signatures of selection in a recent invasion reveals adaptive divergence in a highly vagile invasive species
Cardilini, A. P. A.; Stuart, K. C.; Cassey, P.; Richardson, M. F.; Sherwin, W.; Rollins, L. A.; Sherman, C. D. H.
10.1101/643569 — evolutionary biology — Posted on 2020-05-07
4182 Sleep is bi-directionally modified by amyloid beta oligomers
Ozcan, G. G.; Lim, S.; Leighton, P. L. A.; Allison, W. T.; Rihel, J.
10.1101/610014 — neuroscience — Posted on 2020-05-07
4183 Revealing nonlinear neural decoding by analyzing choices
Yang, Q.; Walker, E. Y.; Cotton, R. J.; Tolias, A. S.; Pitkow, X. S.
10.1101/332353 — neuroscience — Posted on 2020-05-07
4184 Astrocytes promote a protective immune response to brain Toxoplasma gondii infection via IL-33-ST2 signaling
Still, K. M.; Batista, S. J.; O'Brien, C. A.; Oyesola, O. O.; Frueh, S.; Webb, L.; Smirnov, I.; Kovacs, M. A.; Cowan, M. N.; Hayes, N. W.; Thompson, J. A.; Tait Wojno, E. D.; Harris, T. H.
10.1101/338400 — immunology — Posted on 2020-05-07
4185 Mitochondria form contact sites with the nucleus to couple pro-survival retrograde response
Desai, R.; East, D. A.; Hardy, L.; Rigon, M.; Faccenda, D.; Alvarex, M. S.; Singh, A.; Mainenti, M.; Hussey, L. K.; Bentham, R.; Szabadkai, G.; Zappulli, V.; Dhoot, G.; Romano, L. E.; Dong, X.; Coppens, I.; Hamacher-Brady, A.; Chapple, P.; Fleck, R. A.; Vizcay-Barrena, G.; Abeti, R.; Smith, K.; Campanella, M.
10.1101/445411 — cell biology — Posted on 2020-05-07
4187 Characterization of apo-form selective inhibition of indoleamine 2,3-dioxygenase.
Ortiz-Meoz, R. F.; Wang, L.; Matico, R.; Rutkowska, A.; De la Rosa, M.; Bedard, S.; Midgett, R.; Strohmer, K.; Thomson, D.; Zhang, C.; Mebrahtu, M.; Guss, J.; Totoritis, R.; Consler, T.; Campobasso, N.; Taylor, D.; Lewis, T.; Weaver, K.; Mulbaier, M.; Seal, J.; Dunham, R.; Kazmierski, W.; Favre, D.; Bergamini, G.; Shewchuk, L.; Rendina, A.; Zhang, G.
10.1101/324947 — biochemistry — Posted on 2020-05-07
4191 Co-evolution of Eukaryotic-like Vps4 and ESCRT-III Subunits in the Asgard Archaea
Lu, Z.; Fu, T.; Li, T.; Liu, Y.; Zhang, S.; Li, J.; Dai, J.; Koonin, E. V.; Li, G.; Chu, H.; Li, M.
10.1101/2020.05.05.080093 — microbiology — Posted on 2020-05-06
4196 Repurposing low-molecular-weight drugs against the main protease of SARS-CoV-2
Gao, J.; Zhang, L.; Liu, X.; Li, F.; Ma, R.; Zhu, Z.; Zhang, J.; Wu, J.; Shi, Y.; Pan, Y.; Ge, Y.; Ruan, K.
10.1101/2020.05.05.079848 — biochemistry — Posted on 2020-05-06
4198 Expression and function of murine WFDC2 in the respiratory tract.
Bingle, L.; Armes, H.; Williams, D. J.; GIanfrancesco, O.; Chowdhury, M. M. K.; Drapkin, R.; Bingle, C. D.
10.1101/2020.05.05.079293 — genomics — Posted on 2020-05-06
4200 Small protein 26 interacts and enhances glutamine synthetase activity in Methanosarcina mazei
Gutt, M.; Jordan, B.; Weidenbach, K.; Gudzuhn, M.; Kiessling, C.; Cassidy, L.; Helbig, A.; Tholey, A.; Pyper, D.; Schwalbe, H.; Schmitz, R. A.
10.1101/2020.05.06.080432 — biochemistry — Posted on 2020-05-06
4205 Neutralization of SARS-CoV-2 by destruction of the prefusion Spike
Huo, J.; Zhao, Y.; Ren, J.; Zhou, D.; Duyvesteyn, H. M. E.; Ginn, H. M.; Carrique, L.; Malinauskas, T.; Ruza, R. R.; Shah, P. N.; Tan, T. K.; Rijal, P.; Coombes, N.; Bewley, K.; Radecke, J.; Paterson, N. G.; Supasa, P.; Mongkolsapaya, J.; Screaton, G. R.; Carroll, M.; Townsend, A.; Fry, E. E.; Owens, R. J.; Stuart, D. I.
10.1101/2020.05.05.079202 — microbiology — Posted on 2020-05-06
4206 Multiple SARS-CoV-2 introductions shaped the early outbreak in Central Eastern Europe: comparing Hungarian data to a worldwide sequence data-matrix
Kemenesi, G.; Zeghbib, S.; Somogyi, B.; Toth, G. E.; Banyai, K.; Solymosi, N.; Szabo, P. M.; Szabo, I.; Balint, A.; Urban, P.; Herczeg, R.; Gyenesei, A.; Nagy, A.; Pereszlenyi, C. I.; Babinszky, G.; Dudas, G.; Terhes, G.; Zoldi, V.; Lovas, R.; Tenczer, S.; Kornya, L.; Jakab, F.
10.1101/2020.05.06.080119 — microbiology — Posted on 2020-05-06
4207 Inhibition of the replication of SARS-CoV-2 in human cells by the FDA-approved drug chlorpromazine
Plaze, M.; Attali, D.; Prot, M.; Petit, A.-C.; Blatzer, M.; Vinckier, F.; Levillayer, L.; Perin-Dureau, F.; Cachia, A.; Friedlander, G.; Chretien, F.; Simon-Loriere, E.; Gaillard, R.
10.1101/2020.05.05.079608 — microbiology — Posted on 2020-05-06
4211 Conformational maps of human 20S proteasomes reveal PA28- and immuno-dependant inter-ring crosstalks
Lesne, J.; Locard-Paulet, M.; Parra, J.; Zivkovic, D.; Bousquet, M.-P.; Burlet-Schiltz, O.; Marcoux, J.
10.1101/2020.05.05.078170 — biophysics — Posted on 2020-05-06
4212 Condensed chromatin behaves like a solid on the mesoscale in vitro and in living cells
Strickfaden, H.; Tolsma, T.; Sharma, A.; Underhill, D. A.; Hansen, J.; Hendzel, M.
10.1101/2020.05.06.079905 — biochemistry — Posted on 2020-05-06
4213 Methylated PP2A stabilizes Gcn4 to enable a methionine-induced anabolic program
Walvekar, A. S.; Kadamur, G.; Sreedharan, S.; Gupta, R.; Srinivasan, R.; Laxman, S.
10.1101/2020.05.05.079020 — biochemistry — Posted on 2020-05-06
4214 Intravital imaging of islet Ca2+ dynamics reveals enhanced β cell connectivity after bariatric surgery in mice
Akalestou, E.; Suba, K.; Lopez-Noriega, L.; Georgiadou, E.; Chabosseau, P.; Leclerc, I.; Salem, V.; Rutter, G. A.
10.1101/2020.05.05.078725 — cell biology — Posted on 2020-05-06
4216 The oncometabolite L-2-hydroxyglutarate is a common product of Dipteran larval development
Mahmoudzadeh, N. H.; Fitt, A. J.; Schwab, D. B.; Martenis, W. E.; Nease, L. M.; Owings, C. G.; Brinkley, G. J.; Li, H.; Karty, J. A.; Sudarshan, S.; Hardy, R. W.; Picard, C. J.; Moczek, A. P.; Tennessen, J. M.
10.1101/2020.05.05.078857 — developmental biology — Posted on 2020-05-06
4217 Cadherin Preserves Cohesion Across Involuting Tissues During C. elegans Neurulation
Barnes, K. M.; Fan, L.; Moyle, M. W.; Brittin, C. A.; Xu, Y.; Colon-Ramos, D. A.; Santella, A.; Bao, Z.
10.1101/2020.05.05.079301 — developmental biology — Posted on 2020-05-06
4218 Deducing transcriptional kinetics and molecular functions of long non-coding RNAs using allele-sensitive single-cell RNA-sequencing
Johnsson, P. A.; Hartmanis, L.; Ziegenhain, C.; Hendriks, G.-J.; Hagemann-Jensen, M.; Reinius, B.; Sandberg, R.
10.1101/2020.05.05.079251 — genomics — Posted on 2020-05-06
4219 Accurate CYP2D6 genotyping using whole genome sequencing data
Chen, X.; Shen, F.; Gonzaludo, N.; Malhotra, A.; Rogert, C.; Taft, R. J.; Bentley, D. R.; Eberle, M. A.
10.1101/2020.05.05.077966 — bioinformatics — Posted on 2020-05-06
4220 Schizophrenia-associated variation at ZNF804A correlates with altered experience-dependent dynamics of sleep slow-waves and spindles in healthy young adults
Bartsch, U.; Corbin, L. J.; Hellmich, C.; Taylor, M.; Easey, K. E.; Durant, C.; Marston, H. M.; Timpson, N. J.; Jones, M. W.
10.1101/2020.05.01.072165 — neuroscience — Posted on 2020-05-06
4225 The diversity and multiplexity of edge communities within and between brain systems
Jo, Y.; Zamani Esfahlani, F.; Faskowitz, J.; Chumin, E.; Sporns, O.; Betzel, R.
10.1101/2020.05.05.067777 — neuroscience — Posted on 2020-05-06
4227 AAV9 gene therapy restores lifespan and treats pathological and behavioral abnormalities in a mouse model of CLN8-Batten disease
Johnson, T. B.; White, K. A.; Cain, J. T.; Langin, L.; Pratt, M. A.; Brudvig, J. J.; Booth, C. D.; Timm, D. J.; Davis, S. S.; Meyerink, B.; Likhite, S.; Meyer, K.; Weimer, J. M.
10.1101/2020.05.05.079350 — neuroscience — Posted on 2020-05-06
4228 Modulation of neural activity in frontopolar cortex drives reward-based motor learning
Herrojo Ruiz, M.; Maudrich, T.; Kalloch, B.; Sammler, D.; Kenville, R.; Villringer, A.; Sehm, B.; Nikulin, V.
10.1101/2020.05.05.077743 — neuroscience — Posted on 2020-05-06
4229 UPREGULATION OF SUPEROXIDE DISMUTASE 2 BY ASTROCYTES IN THE SIV/MACAQUE MODEL OF HIV-ASSOCIATED NEUROLOGIC DISEASE
Sullivan, M. N.; Brill, S. A.; Mangus, L. M.; Jeong, Y. J.; Solis, C. V.; Knight, A. C.; Colantuoni, C.; Keceli, G.; Paolocci, N.; Queen, S. E.; Mankowski, J. L.
10.1101/2020.05.05.078691 — neuroscience — Posted on 2020-05-06
4231 Tuba1a is uniquely important for axon guidance through midline commissural structures
Buscaglia, G.; Aiken, J.; Hoff, K. J.; Northington, K. R.; Moore, J. K.; Bates, E. A.
10.1101/2020.05.05.079376 — developmental biology — Posted on 2020-05-06
4232 Myosin-X is required for integrin activation at filopodia tips
Miihkinen, M.; Grönloh, M. L. B.; Vihinen, H.; Jokitalo, E.; Goult, B. T.; Ivaska, J.; Jacquemet, G.
10.1101/2020.05.05.078733 — cell biology — Posted on 2020-05-06
4233 Phase-amplitude coupling profiles differ in frontal and auditory cortices
Garcia-Rosales, F.; Lopez-Jury, L.; Gonzalez-Palomares, E.; Cabral-Calderin, Y.; Koessl, M.; Hechavarria, J. C.
10.1101/2020.05.05.078667 — neuroscience — Posted on 2020-05-06
4235 The relationship between fasting-induced torpor,sleep and wakefulness in the laboratory mouse
Vyazovskiy, V. V.; Peirson, S. N.; Foster, R. G.; Huang, Y.-G.; Flaherty, S.; Pothecary, C.
10.1101/2020.05.05.076570 — neuroscience — Posted on 2020-05-06
4236 Volitional Control of Individual Neurons in the Human Brain
Patel, K. V.; Katz, C. N.; Kalia, S. K.; Popovic, M. R.; Valiante, T. A.
10.1101/2020.05.05.079038 — neuroscience — Posted on 2020-05-06
4237 CDNF rescues motor neurons in three animal models of ALS by targeting ER stress
De Lorenzo, F.; Luningschror, P.; Nam, J.; Pilotto, F.; Galli, E.; Lindholm, P.; Rudt von Collenberg, C.; Tii Mungwa, S.; Kauder, J.; Jablonka, S.; Petri, S.; Lindholm, D.; Saxena, S.; Sendtner, M.; Saarma, M.; Voutilainen, M. H.
10.1101/2020.05.05.078618 — neuroscience — Posted on 2020-05-06
4239 Multiple sclerosis iPSC-derived oligodendroglia conserve their intrinsic properties to functionally interact with axons and glia in vivo
Mozafari, S.; Starost, L.; Manot-Saillet, B.; Garcia-Diaz, B.; Xu, Y. K. T.; Roussel, D.; Levy, M. J. F.; Ottoboni, L.; Kim, K.-P.; Scholer, H. R.; Kennedy, T. E.; Antel, J. P.; Martino, G.; Angulo, M. C.; Kuhlmann, T.; Baron-Van Evercooren, A.
10.1101/2020.05.05.078642 — neuroscience — Posted on 2020-05-06
4241 Individualized multi-omic pathway deviation scores using multiple factor analysis
Rau, A.; Manansala, R.; Flister, M.; Rui, H.; Jaffrezic, F.; Laloë, D.; Auer, P.
10.1101/827022 — bioinformatics — Posted on 2020-05-06
4242 Social networks predict the life and death of honey bees
Wild, B.; Dormagen, D. M.; Zachariae, A.; Smith, M. L.; Traynor, K. S.; Brockmann, D.; Couzin, I. D.; Landgraf, T.
10.1101/2020.05.06.076943 — animal behavior and cognition — Posted on 2020-05-06
4244 An integrated personal and population-based Egyptian genome reference
Wohlers, I.; Kuenstner, A.; Munz, M.; Olbrich, M.; Faehnrich, A.; Calonga-Solis, V.; Ma, C.; Hirose, M.; El-Mosallamy, S.; Salama, M.; Busch, H.; Ibrahim, S.
10.1101/681254 — genetics — Posted on 2020-05-06
4245 Platelet miRNA bio-signature discriminates between dementia with Lewy bodies and Alzheimer disease
Gamez-Valero, A.; Campdelacreu, J.; Vilas, D.; Ispierto, L.; Samaniego, D.; Gascon-Bayarri, J.; Rene, R.; Alvarez, R.; Armengol, M. P.; Borras, F. E.; Beyer, K.
10.1101/2020.05.04.075713 — neuroscience — Posted on 2020-05-06
4247 Application of aptamers improves CRISPR-based live imaging of plant telomeres
Khosravi, S.; Schindele, P.; Gladilin, E.; Dunemann, F.; Rutten, T.; Puchta, H.; Houben, A.
10.1101/2020.05.05.078246 — cell biology — Posted on 2020-05-06
4248 Deciphering the temporal heterogeneity of cancer-associated fibroblast subpopulations in breast cancer
Venning, F. A.; Zornhagen, K. W.; Wullkopf, L.; Hajkarim, M. C.; Won, K. J.; Madsen, C. D.; Erler, J. T.
10.1101/2020.05.05.070607 — cancer biology — Posted on 2020-05-06
4250 Integrated requirement of non-specific and sequence-specific DNA binding in MYC-driven transcription
Amati, B.; Filipuzzi, M.; Verrecchia, A.; Doni, M.; Morelli, M. J.; Beaulieu, M.-E.; Soucek, L.; Pellanda, P.; Dalsass, M.; Loffreda, A.; Mazza, D.; Kress, T.; Castillo Cano, V.; Mapelli, M.; Sabo, A.
10.1101/2020.05.04.076190 — molecular biology — Posted on 2020-05-06
4253 A cortical wiring space links cellular architecture, functional dynamics and hierarchies in humans
Paquola, C.; Seidlitz, J.; Benkarim, O.; Royer, J.; Klimes, P.; Bethlehem, R. A. I.; Lariviere, S.; Vos de Wael, R.; Hall, J.; Frauscher, B.; Smallwood, J.; Bernhardt, B.
10.1101/2020.01.08.899583 — neuroscience — Posted on 2020-05-06
4254 Rotavirus Induces Intercellular Calcium Waves Through ADP Signaling
Chang-Graham, A. C.; Perry, J. L.; Engevik, M. A.; Danhof, H. A.; Scribano, F.; Engevik, K. A.; Nelson, J.; Kellen, J. S.; Strtak, A. C.; Palla, N. S.; Estes, M. K.; Versalovic, J.; Britton, R. A.; Hyser, J. M.
10.1101/2019.12.31.892018 — microbiology — Posted on 2020-05-06
4257 A histone-like motif in yellow fever virus contributes to viral replication
Mourao, D.; Chen, S.; Schaefer, U.; Bozzacco, L.; Carneiro, L. A.; Gerber, A.; Adura, C.; Dill, B. D.; Molina, H.; Carroll, T.; Paul, M.; Bhanu, N. V.; Garcia, B. A.; Joberty, G.; Rioja, I.; Prinjha, R. K.; Roeder, R. G.; Rice, C. M.; MacDonald, M. R.; Patel, D. J.; Tarakhovsky, A.
10.1101/2020.05.05.078782 — microbiology — Posted on 2020-05-06
4258 Pou5f3 and Sox19b select gene expression repertoire at Zygotic Genome Activation
Gao, M.; Veil, M.; Rosenblatt, M.; Gebhard, A.; Hass, H.; Buryanova, L.; Yampolsky, L.; Gruening, B. A.; Timmer, J.; Onichtchouk, D.
10.1101/2020.02.16.949362 — developmental biology — Posted on 2020-05-06
4261 Osprey: Open-Source Processing, Reconstruction & Estimation of Magnetic Resonance Spectroscopy Data
Oeltzschner, G.; Zoellner, H. J.; Hui, S. C. N.; Mikkelsen, M.; Saleh, M. G.; Tapper, S.; Edden, R. A. E.
10.1101/2020.02.12.944207 — biochemistry — Posted on 2020-05-06
4264 Metagenomic alterations in gut microbiota precede and predict onset of colitis in the IL10 gene-deficient murine model
Miyoshi, J.; Lee, S. T. M.; Kennedy, M.; Puertolas, M.; Frith, M.; Koval, J. C.; Miyoshi, S.; Antonopoulos, D. A.; Leone, V.; Chang, E. B.
10.1101/2020.05.04.078022 — microbiology — Posted on 2020-05-06
4266 Large-scale pathway-specific polygenic risk, transcriptomic community networks and functional inferences in Parkinson disease
Bandres-Ciga, S.; Saez-Atienzar, S.; Kim, J. J.; Makarious, M.; Faghri, F.; Diez-Fairen, M.; Iwaki, H.; Leonard, H.; Botia, J. A.; Ryten, M.; Hernandez, D.; Gibbs, R.; Ding, J.; Gan-Or, Z.; Noyce, A.; Pihlstrom, L.; Torkamani, A.; Scholz, S. W.; Traynor, B.; Ehrlich, D.; Scherzer, C. R.; Bookman, M.; Cookson, M. R.; Blauwendraat, C.; Nalls, M. A.; Singleton, A.; International Parkinson's Disease Genomics Consortium,
10.1101/2020.05.05.079228 — genetics — Posted on 2020-05-06
4267 HIF1α stability in hypoxia is not oxidant-initiated but can be tuned by redox regulation of the proteasome
Kumar, A.; Vaish, M.; Karuppagounder, S. S.; Gazaryan, I.; Cave, J. W.; Starkov, A. A.; Anderson, E. T.; Zhang, S.; Pinto, J. T.; Rountree, A.; Wang, W.; Sweet, I. R.; Ratan, R. R.
10.1101/2020.05.05.079681 — cell biology — Posted on 2020-05-06
4269 Revealing the high propensity of RNAs to non-specifically bind drug-like small molecules
Kelly, M. L.; Chu, C.-C.; Shi, H.; Ganser, L. R.; Bogerd, H. P.; Huynh, K.; Hou, Y.; Cullen, B. R.; Al-Hashimi, H. M.
10.1101/2020.05.02.074336 — biochemistry — Posted on 2020-05-06
4271 Motile ghosts of the halophilic archaeon, Haloferax volcanii
Kinosita, Y.; Mikami, N.; Li, Z.; Braun, F.; Quax, T. E.; Does, C. v. d.; Ishmukhametov, R.; Albers, S.-V.; Berry, R. M.
10.1101/2020.01.08.899351 — biophysics — Posted on 2020-05-06
4272 STARRPeaker: Uniform processing and accurate identification of STARR-seq active regions
Lee, D.; Shi, M.; Moran, J.; Wall, M.; Zhang, J.; Liu, J.; Fitzgerald, D.; Kyono, Y.; Ma, L.; White, K. P.; Gerstein, M. B.
10.1101/694869 — bioinformatics — Posted on 2020-05-05
4274 Tissue ingrowth markedly reduces mechanical anisotropy and stiffness in fibre direction of highly aligned electrospun polyurethane scaffolds
Krynauw, H.; Buescher, J.; Koehne, J.; Verrijt, L.; Limbert, G.; Davies, N. H.; Bezuidenhout, D.; Franz, T.
10.1101/779942 — bioengineering — Posted on 2020-05-05
4275 Verification of genetic engineering in yeasts with nanopore whole genome sequencing
Collins, J. H.; Keating, K. W.; Jones, T. R.; Balaji, S.; Marsan, C. B.; Como, M.; Newlon, Z. J.; Mitchell, T.; Bartley, B.; Adler, A.; Roehner, N.; Young, E. M.
10.1101/2020.05.05.079368 — synthetic biology — Posted on 2020-05-05
4276 During Aspergillus infection, neutrophil, monocyte-derived DC, and plasmacytoid DC enhance innate immune defense through CXCR3-dependent crosstalk
Guo, Y.; Kasahara, S.; Jhingran, A.; Tosini, N. L.; Zhai, B.; Aufiero, M. A.; Mills, K. A. M.; Gjonbalaj, M.; Espinosa, V.; Rivera, A.; Luster, A. D.; Hohl, T.
10.1101/2020.05.05.079517 — immunology — Posted on 2020-05-05
4279 A SMAD1/5-YAP signaling module drives radial glia self-amplification and growth of the developing cerebral cortex
Najas, S.; Pijuan, I.; Esteve-Codina, A.; Usieto, S.; Martinez, J. D.; Zwijsen, A.; Arbones, M. L.; Marti, E.; Le Dreau, G.
10.1101/558486 — developmental biology — Posted on 2020-05-05
4280 Prochlorococcus phage ferredoxin: structural characterization and electron transfer to cyanobacterial sulfite reductases
Campbell, I. J.; Olmos, J. L.; Xu, W.; Kahanda, D.; Atkinson, J. T.; Sparks, O. N.; Miller, M. D.; Phillips, G. N.; Bennett, G. N.; Silberg, J. J.
10.1101/2020.02.07.937771 — biochemistry — Posted on 2020-05-05
4283 Action enhances predicted touch
Thomas, E. R.; Yon, D.; de Lange, F. P.; Press, C.
10.1101/2020.03.26.007559 — neuroscience — Posted on 2020-05-05
4285 Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance
Schep, R.; Brinkman, E. K.; Leemans, C.; Vergara, X.; Morris, B.; van Schaik, T.; Manzo, S. G.; Peric Hupkes, D.; van den Berg, J.; Beijersbergen, R.; Medema, R. H.; van Steensel, B.
10.1101/2020.05.05.078436 — molecular biology — Posted on 2020-05-05
4287 Phylogenetic analysis of HIV-1 archived DNA in blood and gut-associated lymphoid tissue in patients receiving antiretroviral therapy: a study from Provir/Latitude45 project.
recordon pinson, p.; tumiotto, c.; bellecave, p.; salin, f.; thebault, p.; gosselin, a.; ancuta, p.; soares, m.; routy, j.-p.; fleury, h.
10.1101/2020.05.05.078634 — microbiology — Posted on 2020-05-05
4290 JARID2 and AEBP2 regulate PRC2 activity in the presence of H2A ubiquitination or other histone modifications
Kasinath, V.; Beck, C.; Sauer, P.; Poepsel, S.; Kosmatka, J.; Faini, M.; Toso, D.; Aebersold, R.; Nogales, E.
10.1101/2020.04.20.049213 — biophysics — Posted on 2020-05-05
4293 Naturally occurring cobalamin (B12) analogs can function as cofactors for human methylmalonyl-CoA mutase
Sokolovskaya, O. M.; Plessl, T.; Bailey, H.; Mackinnon, S.; Baumgartner, M. R.; Yue, W. W.; Froese, D. S.; Taga, M. E.
10.1101/2020.03.20.997551 — biochemistry — Posted on 2020-05-05
4296 Phenotypic screening using synthetic CRISPR gRNAs reveals pro-regenerative genes in spinal cord injury
Keatinge, M.; Tsarouchas, T.; Munir, T.; Larraz, J.; Gianni, D.; Tsai, H.-H.; Becker, C. G.; Lyons, D.; Becker, T.
10.1101/2020.04.03.023119 — neuroscience — Posted on 2020-05-05
4297 Electron Microscopic Reconstruction of Neural Circuitry in the Cochlea
Hua, Y.; Ding, X.; Wang, H.; Wang, F.; Gao, Y.; Lu, Y.; Moser, T.; Wu, H.
10.1101/2020.01.04.894816 — neuroscience — Posted on 2020-05-05
4301 Autotrophic and mixotrophic metabolism of an anammox bacterium revealed by in vivo 13C and 2H metabolic network mapping
Lawson, C. E.; Nuijten, G.; de Graaf, R. M.; Jacobson, T. B.; Pabst, M.; Stevenson, D. M.; Jetten, M. S. M.; Noguera, D. R.; McMahon, K. D.; Amador-Noguez, D.; Lücker, S.
10.1101/835298 — microbiology — Posted on 2020-05-05
4305 Generative modelling of the thalamo-cortical circuit mechanisms underlying the neurophysiological effects of ketamine
Shaw, A. D.; Muthukumaraswamy, S. D.; Saxena, N.; Sumner, R. L.; Adams, N.; Moran, R. J.; Singh, K. D.
10.1101/688044 — neuroscience — Posted on 2020-05-05
4306 Taking the sub-lexical route: brain dynamics of reading in the semantic variant of Primary Progressive Aphasia.
Borghesani, V.; Hinkley, L. B.; Ranasinghe, K. G.; Thompson, M.; Shwe, W.; Mizuiri, D.; Lauricella, M.; Europa, E.; Honma, S.; Miller, Z.; Miller, B. L.; Vossel, K.; Henry, M.; Houde, J. F.; Gorno-Tempini, M. L.; Nagarajan, S.
10.1101/847798 — neuroscience — Posted on 2020-05-05
4307 Transneuronal Dpr12/DIP-δ interactions facilitate compartmentalized dopaminergic innervation of Drosophila mushroom body axons
Bornstein, B.; Alyagor, I.; Berkun, V.; Meltzer, H.; Reh, F.; Keren-Shaul, H.; David, E.; Riemensperger, T.; Schuldiner, O.
10.1101/834515 — neuroscience — Posted on 2020-05-05
4309 Transcriptional memory-like imprints and enhanced functional activity in γδ T cells following resolution of malaria infection
Kumarasingha, R.; Ioannidis, L. J.; Abeysekera, W.; Studniberg, S.; Wijesurendra, D.; Mazhari, R.; Poole, D. P.; Mueller, I.; Schofield, L.; Hansen, D. S.; Eriksson, E. M.
10.1101/2020.05.05.078717 — immunology — Posted on 2020-05-05
4310 Unexpected harvesting-induced evolution ofcollective behavior in a fish
Sbragaglia, V.; Klamser, P. P.; Romanczuk, P.; Arlinghaus, R.
10.1101/809442 — ecology — Posted on 2020-05-05
4313 Translating GWAS-identified loci for cardiac rhythm and rate using an in vivo image- and CRISPR/Cas9/based approach
von der Heyde, B.; Emmanouilidou, A.; Mazzaferro, E.; Vicenzi, S.; Hoijer, I.; Klingström, T.; Jumaa, S.; Dethlefsen, O.; Snieder, H.; de Geus, E.; Ameur, A.; Ingelsson, E.; Allalou, A.; Brooke, H. L.; den Hoed, M.
10.1101/385500 — genomics — Posted on 2020-05-05
4320 Translation-associated mutational U-pressure in the first ORF of SARS-CoV-2 and other coronaviruses
Khrustalev, V. V.; Giri, R.; Khrustaleva, T. A.; Kapuganti, S. K.; Stojarov, A. N.; Poboinev, V. V.
10.1101/2020.05.05.078238 — bioinformatics — Posted on 2020-05-05
4322 Test Agreement Between Roche Cobas 6800 and Cepheid GeneXpert Xpress SARS-CoV-2 Assays at High Cycle Threshold Ranges
Broder, K. J.; Babiker, A.; Myers, C.; White, T.; Jones, H.; Cardella, J.; Burd, E. M.; Hill, C. E.; Kraft, C. S.
10.1101/2020.05.05.078501 — microbiology — Posted on 2020-05-05
4324 Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication
Vuong, W.; Khan, M. B.; Fischer, C.; Arutyunova, E.; Lamer, T.; Shields, J.; Saffran, H. A.; McKay, R. T.; van Belkum, M. J.; Joyce, M.; Young, H. S.; Tyrrell, D. L.; Vederas, J. C.; Lemieux, M. J.
10.1101/2020.05.03.073080 — biochemistry — Posted on 2020-05-05
4325 Bulk and single-cell gene expression profiling of SARS-CoV-2 infected human cell lines identifies molecular targets for therapeutic intervention
Wyler, E.; Mösbauer, K.; Franke, V.; Diag, A.; Gottula, L. T.; Arsie, R.; Klironomos, F.; Koppstein, D.; Ayoub, S.; Buccitelli, C.; Richter, A.; Legnini, I.; Ivanov, A.; Mari, T.; Del Giudice, S.; Papies, J. P.; Müller, M. A.; Niemeyer, D.; Selbach, M.; Akalin, A.; Rajewsky, N.; Drosten, C.; Landthaler, M.
10.1101/2020.05.05.079194 — systems biology — Posted on 2020-05-05
4327 Global genetic patterns reveal host tropism versus cross-taxon transmission of bat Betacoronaviruses
Murao, L. E.; Bacus, M. G.; Dayap, S. A. H.; Tampon, N. V. T.; Udarbe, M. M.; Puentespina, R. P.; Villanueva, S. Y. A. M.; de Cadiz, A. E.; Achondo, M. J. M. M.
10.1101/2020.05.04.076281 — evolutionary biology — Posted on 2020-05-05
4328 Identification of Candidate COVID-19 Therapeutics using hPSC-derived Lung Organoids
Han, Y.; Yang, L.; Duan, X.; Duan, F.; Nilsson-Payant, B. E.; Yaron, T. M.; Wang, P.; Tang, X.; Zhang, T.; Zhao, Z.; Bram, Y.; Redmond, D.; Houghton, S.; Nguyen, D.; Xu, D.; Wang, X.; Uhl, S.; Huang, Y.; Johnson, J. L.; Xiang, J.; Wang, H.; Pan, F. C.; Cantley, L. C.; tenOever, B. R.; Ho, D. D.; Evans, T.; Schwartz, R. E.; Chen, H. J.; Chen, S.
10.1101/2020.05.05.079095 — microbiology — Posted on 2020-05-05
4329 Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2
Korber, B.; Fischer, W.; Gnanakaran, S. G.; Yoon, H.; Theiler, J.; Abfalterer, W.; Foley, B.; Giorgi, E. E.; Bhattacharya, T.; Parker, M. D.; Partridge, D. G.; Evans, C. M.; de Silva, T.; LaBranche, C. C.; Montefiori, D. C.; Sheffield COVID-19 Genomics Group,
10.1101/2020.04.29.069054 — evolutionary biology — Posted on 2020-05-05
4331 A Second Generation Leishmanization Vaccine with a Markerless Attenuated Leishmania major Strain using CRISPR gene editing
Zhang, W. W.; Karmakar, S.; Gannavaram, S.; Dey, R.; Lypaczewski, P.; Ismail, N.; Siddiqui, A.; Simonyan, V.; Oliveira, F.; Coutinho-Abreu, I. V.; DeSouza-Vieira, T.; Meneses, C.; Oristian, J.; Serfim, T. D.; Musa, A.; Nakamura, R.; Saljoughian, N.; Volpedo, G.; Satoskar, M.; Satoskar, S.; Dagur, P. K.; McCoy, J. P.; Kamhawi, S.; Valenzuela, J. G.; Hamano, S.; Satoskar, A.; Matlashewski, G.; Nakhasi, H. L.
10.1101/2020.05.04.077115 — microbiology — Posted on 2020-05-05
4335 Ripasudil in a model of pigmentary glaucoma
Wang, C.; Dang, Y.; Waxman, S.; Hong, Y.; Shah, P.; Loewen, R. T.; Xia, X.; Loewen, N.
10.1101/2020.05.04.076760 — pharmacology and toxicology — Posted on 2020-05-05
4341 Malignant Schwann cell precursors mediate intratumoral plasticity in human neuroblastoma
Olsen, T. K.; Otte, J.; Mei, S.; Kameneva, P.; Bjoerklund, A.; Kryukov, E.; Hou, Z.; Johansson, A.; Sundstroem, E.; Martinsson, T.; Fransson, S.; Johnsen, J. I.; Kogner, P.; Adameyko, I.; Kharchenko, P. V.; Baryawno, N.
10.1101/2020.05.04.077057 — cancer biology — Posted on 2020-05-05
4343 MALVIRUS: an integrated web application for viral variant calling
Ciccolella, S.; Denti, L.; Bonizzoni, P.; Della Vedova, G.; Pirola, Y.; Previtali, M.
10.1101/2020.05.05.076992 — bioinformatics — Posted on 2020-05-05
4346 A modular system regulates specialized metabolite pathway branch choice in the medicinal plant Catharanthus roseus
Colinas, M.; Pollier, J.; Vaneechoutte, D.; Malat, D. G.; Schweizer, F.; De Clercq, R.; Guedes, J. G.; Martinez-Cortes, T.; Molina Hidalgo, F. J.; Sottomayor, M.; Vandepoele, K.; Goossens, A.
10.1101/2020.05.04.075671 — plant biology — Posted on 2020-05-05
4347 Mechanism and function of root circumnutation
Taylor, I. W.; Lehner, K. R.; McCaskey, E. N.; Nirmal, N. A.; Ozkan-Aydin, Y.; Murray-Cooper, M.; Jain, R.; Hawkes, E. W.; Ronald, P. C.; Goldman, D. I.; Benfey, P. N.
10.1101/2020.05.04.075127 — plant biology — Posted on 2020-05-05
4349 PHOSPHO1, a novel skeletal regulator of insulin resistance and obesity
Suchacki, K. J.; Morton, N. M.; Vary, C.; Huesa, C.; Yadav, M. C.; Thomas, B. J.; Rajoanah, S.; Bunger, L.; Ball, D.; Barrios-Llerena, M.; Guntur, A. R.; Khavandgar, Z.; Cawthorn, W. P.; Ferron, M.; Karsenty, G.; Murshed, M.; Rosen, C. J.; MacRae, V. E.; Millan, J. L.; Farquharson, C.
10.1101/2020.05.04.075895 — physiology — Posted on 2020-05-05
4350 Targeted bisulfite sequencing: A novel tool for the assessment of DNA methylation with high sensitivity and increased coverage
Moser, D. A.; Mueller, S.; Hummel, E. M.; Limberg, A.; Dieckmann, L.; Frach, L.; Pakusch, J.; Flasbeck, V.; Bruene, M.; Beygo, J.; Klein-Hitpass, L.; Kumsta, R.
10.1101/2020.05.05.078386 — neuroscience — Posted on 2020-05-05
4351 The paraventricular thalamus provides a polysynaptic brake on limbic CRF neurons to sex-dependently blunt binge alcohol drinking and avoidance behavior
Levine, O. B.; Skelly, M. J.; Miller, J. D.; DiBerto, J. F.; Rowson, S. A.; Rivera-Irizarry, J. K.; Kash, T. L.; Pleil, K. E.
10.1101/2020.05.04.075051 — neuroscience — Posted on 2020-05-05
4352 Reconstruction of natural images from responses of primate retinal ganglion cells
Brackbill, N.; Rhoades, C.; Kling, A.; Shah, N. P.; Sher, A.; Litke, A. M.; Chichilnisky, E. J.
10.1101/2020.05.04.077693 — neuroscience — Posted on 2020-05-05
4353 Snca-GFP knock-in mice reflect patterns of endogenous expression and pathological seeding
Caputo, A.; Liang, Y.; Raabe, T. D.; Lo, A.; Horvath, M.; Zhang, B.; Brown, H. J.; Stieber, A.; Luk, K.
10.1101/2020.05.05.077321 — neuroscience — Posted on 2020-05-05
4354 The Proline-rich Domain Promotes Tau Liquid Liquid Phase Separation in Cells
Zhang, X.; Vigers, M.; McCarty, J.; Rauch, J. N.; Fredrickson, G. H.; Wilson, M. Z.; Shea, J.-E.; Han, S.; Kosik, K.
10.1101/2020.05.04.076968 — neuroscience — Posted on 2020-05-05
4355 Region-Specific PSD-95 Interactomes Contribute to Functional Diversity of Excitatory Synapses in Human Brain.
Funk, A.; Labilloy, G.; Reigle, J.; Alnafisah, R.; Heaven, M.; Roberts, R.; Shamsaei, B.; Greis, K.; Meller, J.; McCullumsmith, R.
10.1101/2020.05.04.076844 — neuroscience — Posted on 2020-05-05
4359 Brain/MINDS Beyond Human Brain MRI Study: Multi-Site Harmonization for Brain Disorders Throughout the Lifespan
Koike, S.; Tanaka, S.; Okada, T.; Aso, T.; Asano, M.; Maikusa, N.; Morita, K.; Okada, N.; Fukunaga, M.; Uematsu, A.; Togo, H.; Miyazaki, A.; Murata, K.; Urushibata, Y.; Autio, J. A.; Ose, T.; Yoshiomoto, J.; Araki, T.; Glasser, M. F.; Van Essen, D. C.; Murayama, M.; Sadato, N.; Kawato, M.; Kasai, K.; Okamoto, Y.; Hanakawa, T.; Hayashi, T.; Brain/MINDS Beyond Human Brain MRI Group,
10.1101/2020.05.05.076273 — neuroscience — Posted on 2020-05-05
4362 Metagenomic alterations in gut microbiota precede and predict onset of colitis in the IL10 gene-deficient murine model
Miyoshi, J.; Lee, S. T. M.; Kennedy, M.; Puertolas, M.; Frith, M.; Koval, J. C.; Miyoshi, S.; Antonopoulos, D. A.; Leone, V.; Chang, E. B.
10.1101/2020.05.04.078022 — microbiology — Posted on 2020-05-05
4363 Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure
Smith, D. A.; Magri, A.; Bowden, R.; Chaturvedi, N.; Fellay, J.; McLauchlan, J.; Foster, G. R.; Irving, W. L.; STOP-HCV Consortium, ; Simmonds, P.; Pedergnana, V.; Barnes, E.; Ansari, M. A.
10.1101/2020.05.05.077230 — microbiology — Posted on 2020-05-05
4364 E prostanoid receptor 4 expressing macrophages promote the regeneration of the intestinal epithelial barrier upon inflammation
Na, Y. R.; Jung, D.; Stakenborg, M.; Gu, G. J.; Jeong, M. R.; Jang, H. R.; Suh, S. Y.; Kim, H. J.; Kwon, Y. H.; Sung, T. S.; Ryoo, S. B.; Park, K. J.; Im, J. P.; Park, J. Y.; Lee, Y. S.; Han, H. J.; Park, B. Y.; Lee, S. W.; Lee, H. S.; Cleynen, I.; Matteoli, G.; Seok, S. H.
10.1101/2020.05.04.077412 — immunology — Posted on 2020-05-05
4366 Genoppi: an open-source software for robust and standardized integration of proteomic and genetic data
Pintacuda, G.; Lassen, F. H.; Hsu, Y.-H. H.; Kim, A.; Martin, J. M.; Malolepsza, E.; Lim, J. K.; Fornelos, N.; Eggan, K. C.; Lage, K.
10.1101/2020.05.04.076034 — genetics — Posted on 2020-05-05
4367 CHOP-c-JUN complex plays a critical role in liver proteotoxicity induced by mutant Z alpha-1 antitrypsin.
Attanasio, S.; Gernoux, G.; Ferriero, R.; De Cegli, R.; Carissimo, A.; Nusco, E.; Campione, S.; Teckman, J.; Piccolo, P.; Brunetti-Pierri, N.
10.1101/2020.05.04.076752 — genetics — Posted on 2020-05-05
4368 High resolution imaging of nascent mitochondrial protein synthesis in cultured human cells.
Zorkau, M.; Albus, C.; Berlinguer-Palmini, R.; Chrzanowska-Lightowlers, Z. M.; Lightowlers, R. N.
10.1101/2020.05.05.076109 — cell biology — Posted on 2020-05-05
4372 Heritability of visual cortex architecture and perception
Alvarez, I.; Finlayson, N. J.; Ei, S.; de Haas, B.; Greenwood, J. A.; Schwarzkopf, D. S.
10.1101/2020.05.04.077545 — neuroscience — Posted on 2020-05-05
4374 Removal of the extracellular matrix biases auditory cortical layer dynamics towards supragranular corticocortical integration
EL Tabbal, M.; Niekisch, H.; Henschke, J. J.; Budinger, E.; Frischknecht, R.; Deliano, M.; Happel, M. F. K.
10.1101/2020.05.04.076224 — neuroscience — Posted on 2020-05-05
4375 Pathologic α-Synuclein Species Activate LRRK2 in Pro-Inflammatory Monocyte and Macrophage Responses
Xu, E.; Boddu, R.; Abdelmotilib, H. A.; Kelly, K.; Sokratian, A.; Harms, A. S.; Schonhoff, A. M.; Bryant, N.; Harmsen, I. E.; Schlossmacher, M.; Chandra, S.; Krendelshchikova, V.; Liu, Z.; West, A. B.
10.1101/2020.05.04.077065 — neuroscience — Posted on 2020-05-05
4377 Prm2 deficiency triggers a Reactive Oxygen Species (ROS)-mediated destruction cascade during epididymal sperm maturation in mice
Schneider, S.; Shakeri, F.; Troetschel, C.; Arevalo, L.; Kruse, A.; Buness, A.; Poetsch, A.; Steger, K.; Schorle, H.
10.1101/2020.05.05.075929 — molecular biology — Posted on 2020-05-05
4379 Improved growth and morphological plasticity of Haloferax volcanii
de Silva, R. T.; Abdul Halim, M. F.; Pittrich, D. A.; Brown, H. J.; Pohlschroder, M.; Duggin, I. G.
10.1101/2020.05.04.078048 — microbiology — Posted on 2020-05-05
4382 Pre-TCR signaling intensity shapes the TCRβ repertoire
Bovolenta, E. R.; Garcia-Cuesta, E. M.; Ponomarenko, J.; Mellado, M.; Castro, M.; Abia, D.; van Santen, H. M.
10.1101/2020.05.04.074922 — immunology — Posted on 2020-05-05
4384 Type III interferons disrupt the lung epithelial barrier upon viral recognition.
Broggi, A.; Ghosh, S.; Sposito, B.; Spreafico, R.; Balzarini, F.; Lo Cascio, A.; Clementi, N.; De Santis, M.; Mancini, N.; Granucci, F.; Zanoni, I.
10.1101/2020.05.05.077867 — immunology — Posted on 2020-05-05
4388 SMARCB1 loss interacts with neuronal differentiation state to block maturation and impact cell stability
Parisian, A. D.; Koga, T.; Miki, S.; Johann, P. D.; Kool, M.; Crawford, J. R.; Furnari, F.
10.1101/2020.05.04.074443 — cancer biology — Posted on 2020-05-05
4391 Chemically-informed Analyses of Metabolomics Mass Spectrometry Data with Qemistree
Tripathi, A.; Vazquez-Baeza, Y.; Gauglitz, J. M.; Wang, M.; Duhrkop, K.; Esposito-Nothias, M.; Acharya, D.; Ernst, M.; van der Hooft, J. J. J.; Zhu, Q.; McDonald, D.; Gonzalez, A.; Handelsman, J.; Fleischauer, M.; Ludwig, M.; Bocker, S.; NOTHIAS, L. F.; Knight, R.; Dorrestein, P. C.
10.1101/2020.05.04.077636 — bioinformatics — Posted on 2020-05-05
4401 Functional traits of three Ulmus minor fungal endophytes and their role in host resistance to Ophiostoma novo-ulmi
Martinez-Arias, C.; Sobrino-Plata, J.; Ormeno-Moncalvillo, S.; Gil, L.; Rodriguez-Calcerrada, J.; Martin, J. A.
10.1101/2020.05.04.076349 — plant biology — Posted on 2020-05-05
4403 Single Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis
Henriques, F.; Bedard, A. H.; Guilherme, A.; Kelly, M.; Chi, J.; Zhang, P.; Lifshitz, L. M.; Bellve, K.; Rowland, L.; Yenilmez, B.; Kumar, S.; Wang, Y.; Luban, J.; Weinstein, L. S.; Lin, J. D.; Cohen, P.; Czech, M. P.
10.1101/2020.05.04.077529 — physiology — Posted on 2020-05-05
4407 Transcription of intragenic CpG islands influences spatiotemporal host gene pre-mRNA processing
Amante, S. M.; Montibus, B.; Cowley, M.; Barkas, N.; Setiadi, J.; Saadeh, H.; Giemza, J.; Contreras-Castillo, S.; Fleischanderl, K.; Schulz, R.; Oakey, R. J.
10.1101/2020.05.04.076729 — molecular biology — Posted on 2020-05-05
4410 Highly accurate long-read HiFi sequencing data for five complex genomes
Hon, T.; Mars, K.; Young, G.; Tsai, Y.-C.; Karalius, J. W.; Landolin, J. M.; Maurer, N.; Kudrna, D.; Hardigan, M. A.; Steiner, C. C.; Knapp, S. J.; Ware, D.; Shapiro, B.; Peluso, P.; Rank, D. R.
10.1101/2020.05.04.077180 — genomics — Posted on 2020-05-05
4411 Examining sex-differentiated genetic effects across neuropsychiatric and behavioral traits
Martin, J.; Khramtsova, E. A.; Goleva, S. B.; Blokland, G. A. M.; Traglia, M.; Walters, R. K.; Hübel, C.; Coleman, J. R. I.; Breen, G.; Borglum, A.; Demontis, D.; Grove, J.; Werge, T.; Bralten, J.; Bulik, C.; Lee, P. H.; Mathews, C. A.; Peterson, R. E.; Winham, S. J.; Wray, N. R.; Edenberg, H. J.; Guo, W.; Yao, Y.; Neale, B.; Faraone, S. V.; Petryshen, T. L.; Weiss, L.; Duncan, L.; Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium, ; Goldstein, J. M.; Smoller, J. W.; Stranger, B.; Davis, L. K.
10.1101/2020.05.04.076042 — genetics — Posted on 2020-05-05
4412 Change in terrestrial human footprint drives continued loss of intact ecosystems
Williams, B. A.; Venter, O.; Allan, J. R.; Atkinson, S.; Rehbein, J. A.; Ward, M. S.; Di Marco, M.; Grantham, H. S.; Erivin, J.; Goetz, S.; Hansen, A.; Jantz, P.; Pillay, R.; Rodriguez-Buritica, S.; Supples, C.; Virnig, A. L. S.; Watson, J. E. M.
10.1101/2020.05.04.077818 — ecology — Posted on 2020-05-05
4413 Hallmarks of basidiomycete soft- and white-rot in wood-decay -omics data of Armillaria
Sahu, N.; Merenyi, Z.; Balint, B.; Kiss, B.; Sipos, G.; Owens, R.; Nagy, L. G.
10.1101/2020.05.04.075879 — ecology — Posted on 2020-05-05
4418 Three-Dimensional (3D) Fibronectin Nano-Array Presented on Fibrin Matrix Accelerates Mice Skin Wound Healing
Jara, C. P.; Wang, O.; Prado, T. P. d.; Ismail, A.; Fabian, F. M.; Li, H.; Velloso, L. A.; Carlson, M. A.; Burgess, W.; Lei, Y.; Velander, W. H.; Araujo, E. P.
10.1101/2020.05.04.077891 — bioengineering — Posted on 2020-05-05
4420 Direct and specific assessment of axonal injury and spinal cord microenvironments using diffusion correlation imaging
Benjamini, D.; Hutchinson, E. B.; Komlosh, M. E.; Comrie, C. J.; Schwerin, S. C.; Zhang, G.; Pierpaoli, C.; Basser, P. J.
10.1101/2020.05.04.074856 — neuroscience — Posted on 2020-05-05
4422 Network-based atrophy modelling in the common epilepsies: a worldwide ENIGMA study
Lariviere, S.; Rodriguez-Cruces, R.; Royer, J.; Caligiuri, M. E.; Gambardella, A.; Concha, L.; Keller, S. S.; Cendes, F.; Yasuda, C.; Bonilha, L.; Gleichgerrcht, E.; Focke, N. K.; Domin, M.; von Podewills, F.; Langner, S.; Rummel, C.; Wiest, R.; Martin, P.; Kotikalapudi, R.; O.Brien, T. J.; Sinclair, B.; Vivash, L.; Desmond, P. M.; Alhusaini, S.; Doherty, C. P.; Cavalleri, G. L.; Delanty, N.; Kälviäinen, R.; Jackson, G. D.; Kowalczyk, M.; Mascalchi, M.; Semmelroch, M.; Thomas, R. H.; Soltanian-Zadeh, H.; Davoodi-Bojd, E.; Zhang, J.; Lenge, M.; Guerrini, R.; Bartolini, E.; Hamandi, K.; Foley,
10.1101/2020.05.04.076836 — neuroscience — Posted on 2020-05-05
4423 A GRAB sensor reveals activity-dependent non-vesicular somatodendritic adenosine release
Wu, Z.; Cui, Y.; Wang, H.; Song, K.; Yuan, Z.; Dong, A.; Wu, H.; Wan, Y.; Pan, S.; Peng, W.; Jing, M.; Xu, M.; Luo, M.; Li, Y.
10.1101/2020.05.04.075564 — neuroscience — Posted on 2020-05-05
4425 Determinants of RNA recognition by the FinO domain of the Escherichia coli ProQ protein
Stein, E. M.; Kwiatkowska, J.; Basczok, M. M.; Gravel, C. M.; Berry, K. E.; Olejniczak, M.
10.1101/2020.05.04.075150 — molecular biology — Posted on 2020-05-05
4427 Type I and III interferons disrupt lung epithelial repair during recovery from viral infection
Major, J.; Crotta, S.; Llorian, M.; McCabe, T. M.; Gad, H. H.; Hartmann, R.; Wack, A.
10.1101/2020.05.05.078360 — immunology — Posted on 2020-05-05
4428 Allele-specific alternative splicing in human tissues
Amoah, K.; Hsiao, Y.-H. E.; Bahn, J. H.; Sun, Y.; Burghard, C.; Tan, B. X.; Yang, E.-W.; Xiao, X.
10.1101/2020.05.04.077255 — genomics — Posted on 2020-05-05
4432 Combining network-guided GWAS to discover susceptibility mechanisms for breast cancer
Climente-Gonzalez, H.; Lonjou, C.; Lesueur, F.; GENESIS Study collaborators, ; Stoppa-Lyonnet, D.; Andrieu, N.; Azencott, C.-A.
10.1101/2020.05.04.076661 — genetics — Posted on 2020-05-05
4436 A pan-cancer atlas of transcriptional dependence on DNA methylation and copy number aberrations
Fougner, C.; Höglander, E. K.; Lien, T. G.; Sorlie, T.; Nord, S.; Lingjaerde, O. C.
10.1101/2020.05.04.076901 — genomics — Posted on 2020-05-05
4438 Just Add Data: Automated Predictive Modeling and BioSignature Discovery
Tsamardinos, I.; Charonyktakis, P.; Lakiotaki, K.; Borboudakis, G.; Zenklusen, J. C.; Juhl, H.; Chatzaki, E.; Lagani, V.
10.1101/2020.05.04.075747 — bioinformatics — Posted on 2020-05-05
4440 Importin α2 associates with chromatin via a novel DNA binding domain
Jibiki, K.; Kodama, T.; Suenaga, A.; Kawase, Y.; Shibazaki, N.; Nomoto, S.; Nagasawa, S.; Nagashima, M.; Shimodan, S.; Kikuchi, R.; Saitoh, N.; Yoneda, Y.; Akagi, K.-i.; Yasuhara, N.
10.1101/2020.05.04.075580 — molecular biology — Posted on 2020-05-05
4444 Clusterin secretion is attenuated by pro-inflammatory cytokines in culture models of cartilage degradation
Matta, C.; Fellows, C. R.; Quasnichka, H.; Williams, A.; Jeremiasse, B.; Allaway, D.; Mobasheri, A.
10.1101/2020.05.05.078105 — molecular biology — Posted on 2020-05-05
4447 Rapid T cell receptor interaction grouping with ting
Mölder, F.; Stervbo, U.; Loyal, L.; Bacher, P.; Babel, N.; Rahmann, S.
10.1101/2020.05.04.069914 — bioinformatics — Posted on 2020-05-05
4451 Automatic deep learning driven label-free image guided patch clamp system for human and rodent in vitro slice physiology
Koos, K.; Olah, G.; Balassa, T.; Mihut, N.; Rozsa, M.; Ozsvar, A.; Tasnadi, E.; Barzo, P.; Farago, N.; Puskas, L.; Molnar, G.; Molnar, J.; Tamas, G.; Horvath, P.
10.1101/2020.05.05.078162 — neuroscience — Posted on 2020-05-05
4461 Vanishing white matter disease expression of truncated EIF2B5 activates induced stress response
Keefe, M.; Soderholm, H.; Shih, H.-Y.; Stevenson, T.; Glaittli, K.; Bowles, D. M.; Scholl, E.; Colby, S.; Merchant, S.; Hsu, E.; Bonkowsky, J.
10.1101/2020.05.05.078295 — physiology — Posted on 2020-05-05
4463 CoNNECT: Convolutional Neural Network for Estimating synaptic Connectivity from spike Trains
Endo, D.; Kobayashi, R.; Bartolo, R.; Averbeck, B. B.; Sugase-Miyamoto, Y.; Hayashi, K.; Kenji, K.; Richmond, B. J.; Shinomoto, S.
10.1101/2020.05.05.078089 — neuroscience — Posted on 2020-05-05
4465 A molecular atlas of proximal airway identifies subsets of known airway cell types revealing details of the unique molecular pathogenesis of Cystic Fibrosis
Carraro, G.; Langerman, J.; Sabri, S.; Lorenzana, Z.; Purkayastha, A.; Konda, B.; Aros, C. J.; Calvert, B. A.; Szymaniak, A.; Wilson, E.; Mulligan, M.; Bhatt, P.; Vijayaraj, P.; Yao, C.; Shia, D. W.; Israely, E.; Rickabaugh, T. M.; Mense, M.; Randell, S. H.; Vladar, E. K.; Ryan, A. L.; Plath, K.; Mahoney, J.; Stripp, B. R.; Gomperts, B. N.
10.1101/2020.05.01.072876 — cell biology — Posted on 2020-05-05
4466 SH3KBP1 scaffolds endoplasmic reticulum and controls skeletal myofibers architecture and integrity
Guiraud, A.; Christin, E.; Couturier, N.; Kretz-Remy, C.; Janin, A.; Ghasemizadeh, A.; Durieux, A.-C.; Arnould, D.; Romero, N.; Bui, T. M.; Buchman, V.; Julien, L.; Bitoun, M.; Gache, V.
10.1101/2020.05.04.076208 — cell biology — Posted on 2020-05-05
4468 Close encounters of the three morphs: does color affect aggression in a polymorphic lizard?
Scali, S.; Mangiacotti, M.; Sacchi, R.; Coladonato, A. J.; Falaschi, M.; Saviano, L.; Rampoldi, M. G.; Crozi, M.; Perotti, C.; Zucca, F.; Gozzo, E.; Zuffi, M. A.
10.1101/2020.05.02.074146 — animal behavior and cognition — Posted on 2020-05-05
4469 Robust Inference of Kinase Activity using Functional Networks
Yilmaz, S.; Ayati, M.; Schlatzer, D.; Cicek, A. E.; Chance, M.; Koyuturk, M.
10.1101/2020.05.01.062802 — systems biology — Posted on 2020-05-05
4470 PARP12-catalyzed mono-ADP-ribosylation of Golgin-97 controls the transport of E-cadherin
Grimaldi, G.; Schembri, L.; Lo Monte, M.; Spano, D.; Di Martino, R.; Beccari, A. R.; Valente, C.; Corda, D.
10.1101/2020.05.05.078097 — cell biology — Posted on 2020-05-05
4477 ALKBH7 mediates necrosis via rewiring of glyoxal metabolism
Kulkarni, C.; Nadtochiy, S. M.; Kennedy, L.; Zhang, J.; Chhim, S.; Alwaseem, H.; Murphy, E.; Fu, D.; Brookes, P. S.
10.1101/2020.05.04.077297 — cell biology — Posted on 2020-05-05
4478 Lipogenesis and innate immunity in hepatocellular carcinoma cells reprogrammed by an isoenzyme switch of hexokinases
Perrin-Cocon, L.; Vidalain, P.-O.; Jacquemin, C.; Aublin-Gex, A.; Olmstead, K.; Panthu, B.; Rautureau, G. J. P.; Andre, P.; Nyczka, P.; Hutt, M.-T.; Amoedo, N.; Rossignol, R.; Filipp, F. V.; Lotteau, V.; Diaz, O.
10.1101/2020.03.13.973321 — cancer biology — Posted on 2020-05-05
4480 P2X-GCaMPs as versatile tools for imaging extracellular ATP signaling
Ollivier, M.; Beudez, J.; Linck, N.; Grutter, T.; Compan, V.; Rassendren, F.
10.1101/2020.04.23.057513 — neuroscience — Posted on 2020-05-05
4481 Mass spectrometric method for the unambiguous profiling of cellular dynamic glycosylation.
Shajahan, A.; Supekar, N. T.; Wu, H.; Wands, A. M.; Bhat, G.; Kalimurthy, A.; Matsubara, M.; Ranzinger, R.; Kohler, J. J.; Azadi, P.
10.1101/2020.05.04.075655 — biochemistry — Posted on 2020-05-05
4482 Syndecan 2 regulates hematopoietic lineages and infection resolution in zebrafish
Sharma Lamichhane, B.; Bisgrove, B. W.; Su, Y.-C.; Demarest, B. L.; Yost, H. J.
10.1101/2020.05.04.076786 — developmental biology — Posted on 2020-05-05
4483 SerraNA: a program to determine nucleic acids elasticity from simulation data
Velasco-Berrelleza, V.; Burman, M.; Shepherd, J. W.; Leake, M. C.; Golestanian, R.; Noy, A.
10.1101/2020.03.24.004945 — biophysics — Posted on 2020-05-05
4488 Phosphorylation and dephosphorylation of Ser852 and Ser889 control clustering, localization, and function of PAR-3
Yamashita, K.; Mizuno, K.; Furukawa, K.; Hirose, H.; Sakurai, N.; Masuda-Hirata, M.; Amano, Y.; Hirose, T.; Suzuki, A.; Ohno, S.
10.1101/2020.05.04.075952 — cell biology — Posted on 2020-05-05
4490 HGF-induced activation of NEPHRIN and NEPH1 serves as a novel mechanism for recovery of podocytes from injury
Solanki, A. K.; Srivastava, P.; Arif, E.; Furcht, C. M.; Rahman, B.; Wen, P.; Singh, A.; Holzman, L. B.; Fitzgibbon, W. R.; Lobo, G.; Lipschutz, J. H.; Kwon, S.-H.; Han, Z.; Lazzara, M. J.; Nihalani, D.
10.1101/2020.05.04.077941 — cell biology — Posted on 2020-05-05
4491 Oncogenic GLI1 and STAT1/3 activation drives immunosuppressive tryptophan/kynurenine metabolism via synergistic induction of IDO1 in skin cancer cells
Elmer, D. P.; Strobl, V.; Stockmaier, G.; Dang, H.-H.; Wiederstein, M.; Licha, D.; Strobl, A.; Sternberg, C.; Tesanovic, S.; Grund-Groeschke, S.; Gruber, W.; Wolff, F.; Moriggl, R.; Risch, A.; Reischl, R.; Huber, C. G.; Horejs-Hoeck, J.; Aberger, F.
10.1101/2020.05.04.074757 — cancer biology — Posted on 2020-05-05
4495 Impact of formate supplementation on body weight and plasma amino acids
Dhayade, S.; Pietzke, M.; Wiesheu, R.; Tait-Mulder, J.; Athineos, D.; Sumpton, D.; Coffelt, S. B.; Blyth, K.; Vazquez, A. B.
10.1101/2020.05.04.075796 — biochemistry — Posted on 2020-05-05
4496 Primitive RNA-catalysis with guanine-rich oligonucleotide sequences - the case of a (GGC)3 nonamer
Costanzo, G.; Cirigliano, A.; Pino, S.; Giorgi, A.; Sedo, O.; Zdrahal, Z.; Stadlbauer, P.; Sponer, J.; Sponer, J.; Di Mauro, E.
10.1101/2020.05.04.075614 — biochemistry — Posted on 2020-05-05
4497 Crystal Structure of the Werner's Syndrome Helicase
Newman, J. A.; Gavard, A. E.; Lieb, S.; Ravichandran, M. C.; Hauer, K.; Werni, P.; Geist, L.; Boettcher, J.; Engen, J. R.; Rumpel, K.; Samwer, M.; Petronczki, M.; Gileadi, O.
10.1101/2020.05.04.075176 — biochemistry — Posted on 2020-05-05
4499 Impact of tumor-parenchyma biomechanics on liver metastatic progression: a multi-model approach
Wang, Y.; Brodin, E.; Nishii, K.; Frieboes, H. B.; Mumenthaler, S.; Sparks, J. L.; Macklin, P.
10.1101/2020.05.04.074989 — systems biology — Posted on 2020-05-05
4504 Bioengineered human skeletal muscle with a Pax7+ satellite cell niche capable of functional regeneration
Fleming, J. W.; Capel, A. J.; Rimingtion, R. P.; Wheeler, P.; Davies, O. G.; Lewis, M. P.
10.1101/2020.05.04.076828 — cell biology — Posted on 2020-05-05
4505 Closure motif-mediated state changes of the HORMA protein ASY1
Yang, C.; Hu, B.; Portheine, S. M.; Chuenban, P.; Schnittger, A.
10.1101/2020.05.04.064501 — cell biology — Posted on 2020-05-05
4508 Mechanical dysfunction induced by a hypertrophic cardiomyopathy mutation is the primary driver of cellular adaptation
Clippinger, S. R.; Cloonan, P. E.; Wang, W.; Greenberg, L.; Stump, W. T.; Angsutararux, P.; Nerbonne, J. M.; Greenberg, M. J.
10.1101/2020.05.04.067181 — biophysics — Posted on 2020-05-05
4510 Decomposing Loss Aversion from Gaze Allocation and Pupil Dilation
Sheng, F.; Ramakrishnan, A.; Darsol, S.; Zhao, W. J.; Thelaus, S.; Cen, P.; Platt, M.
10.1101/2020.02.27.967711 — neuroscience — Posted on 2020-05-05
4512 Transcriptome-wide sites of collided ribosomes reveal principles of translational pausing
Arpat, A. B.; Liechti, L. A.; De Matos, M.; Dreos, R.; Janich, P.; Gatfield, D.
10.1101/710061 — cell biology — Posted on 2020-05-05
4513 The irradiated brain microenvironment supports glioma stemness and survival via astrocyte-derived Transglutaminase 2
Berg, T. J.; Marques, C.; Pantazopoulou, V.; Johansson, E.; von Stedingk, K.; Lindgren, D.; Pietras, E. J.; Bergström, T.; Swartling, F. J.; Governa, V.; Bengzon, J.; Belting, M.; Axelson, H.; Squatrito, M.; Pietras, A.
10.1101/2020.02.12.945329 — cancer biology — Posted on 2020-05-05
4515 Low protein intake compromises the recovery of lactation-induced bone loss in female mouse dams without affecting skeletal muscles.
Kanakis, I.; Alameddine, M.; Scalabrin, M.; van 't Hof, R. J.; Liloglou, T.; Ozanne, S. E.; Goljanek-Whysall, K.; Vasilaki, A.
10.1101/2020.05.02.073759 — physiology — Posted on 2020-05-05
4517 Single Cell RNA-Sequencing-based Analysis of CD4+ T-Cell Subset-Specific Susceptibility to Transcriptional Modulation by HIV-1 Latency-Reversing Agents
Kazmierski, J.; Postmus, D.; Wyler, E.; Fischer, C.; Jansen, J.; Meixenberger, K.; Vitcetz, S.; Sohn, M.; Sauer, S.; Bannert, N.; Landthaler, M.; GOFFINET, C.
10.1101/2020.05.04.075119 — microbiology — Posted on 2020-05-05
4518 Advancing pre-clinical species genetic utility through a high-quality assembly of the cynomolgus monkey (Macaca fascicularis) genome
Oziolor, E. M.; Sullivan, S.; Mangelson, H.; Eacker, S. M.; Agostino, M.; Whiteley, L. O.; Cook, J.; Koza-Taylor, P.
10.1101/2020.05.01.072280 — genomics — Posted on 2020-05-05
4519 Deciphering cattle temperament measures derived from a four-platform standing scale using genetic factor analytic modeling
Yu, H.; Morota, G.; Celestino, E. F.; Dahlen, C. R.; Wagner, S. A.; Riley, D. G.; Hulsman Hanna, L. L.
10.1101/2020.01.20.913343 — genetics — Posted on 2020-05-05
4527 Multi-modal characterization and simulation of human epileptic circuitry
Buchin, A.; de Frates, R.; Nandi, A.; Mann, R.; Chong, P.; Ng, L.; Miller, J.; Hodge, R. D.; Kalmbach, B.; Bose, S.; Rutishauser, U.; McConoughey, S.; Lein, E.; Berg, J.; Sorensen, S.; Gwinn, R.; Koch, C.; Ting, J. T.; Anastassiou, C. A.
10.1101/2020.04.24.060178 — neuroscience — Posted on 2020-05-05
4528 Multi-modal characterization and simulation of human epileptic circuitry
Buchin, A.; de Frates, R.; Nandi, A.; Mann, R.; Chong, P.; Ng, L.; Miller, J.; Hodge, R. D.; Kalmbach, B.; Bose, S.; Rutishauser, U.; McConoughey, S.; Lein, E.; Berg, J.; Sorensen, S.; Gwinn, R.; Koch, C.; Ting, J. T.; Anastassiou, C. A.
10.1101/2020.04.24.060178 — neuroscience — Posted on 2020-05-05
4529 An implicit memory of errors limits human sensorimotor adaptation
Albert, S. T.; Jang, J.; Sheahan, H. R.; Teunissen, L.; Vandevoorde, K.; Shadmehr, R.
10.1101/868406 — neuroscience — Posted on 2020-05-05
4530 An implicit memory of errors limits human sensorimotor adaptation
Albert, S. T.; Jang, J.; Sheahan, H. R.; Teunissen, L.; Vandevoorde, K.; Shadmehr, R.
10.1101/868406 — neuroscience — Posted on 2020-05-05
4533 Host adaptations in the fixLJ pathway of the Burkholderia cepacia complex increase virulence
Schaefers, M. M.; Wang, B. X.; Boisvert, N. M.; Martini, S. J.; Bonney, S. L.; Marshall, C. W.; Laub, M. T.; Cooper, V. S.; Priebe, G. P.
10.1101/2020.05.04.070367 — microbiology — Posted on 2020-05-05
4534 Global Genetic Cartography of Urban Metagenomes andAnti-Microbial Resistance
Danko, D. C.; Bezdan, D.; Afshinnekoo, E.; Ahsanuddin, S.; Alicea, J.; Bhattacharya, C.; Bhattacharyya, M.; Blekhman, R.; Butler, D. J.; Castro-Nallar, E.; Canas, A. M.; Chatziefthimiou, A. D.; Chng, K. R.; Coil, D. A.; Court, D. S.; Crawford, R. W.; Desnues, C.; Dias-Neto, E.; Donnellan, D.; Dybwad, M.; Eisen, J. A.; Elhaik, E.; Ercolini, D.; De Filippis, F.; Frolova, A.; Graf, A. B.; Green, D. C.; Lee, P. K. H.; Hecht, J.; Hernandez, M.; Jang, S.; Kahles, A.; Karasikov, M.; Knights, K.; Kyrpides, N. C.; Ljungdahl, P.; Lyons, A.; Mason-Buck, G.; McGrath, K.; Mongodin, E. F.; Mustafa, H.; Muta
10.1101/724526 — microbiology — Posted on 2020-05-05
4535 Global Genetic Cartography of Urban Metagenomes andAnti-Microbial Resistance
Danko, D. C.; Bezdan, D.; Afshinnekoo, E.; Ahsanuddin, S.; Alicea, J.; Bhattacharya, C.; Bhattacharyya, M.; Blekhman, R.; Butler, D. J.; Castro-Nallar, E.; Canas, A. M.; Chatziefthimiou, A. D.; Chng, K. R.; Coil, D. A.; Court, D. S.; Crawford, R. W.; Desnues, C.; Dias-Neto, E.; Donnellan, D.; Dybwad, M.; Eisen, J. A.; Elhaik, E.; Ercolini, D.; De Filippis, F.; Frolova, A.; Graf, A. B.; Green, D. C.; Lee, P. K. H.; Hecht, J.; Hernandez, M.; Jang, S.; Kahles, A.; Karasikov, M.; Knights, K.; Kyrpides, N. C.; Ljungdahl, P.; Lyons, A.; Mason-Buck, G.; McGrath, K.; Mongodin, E. F.; Mustafa, H.; Muta
10.1101/724526 — microbiology — Posted on 2020-05-05
4536 The histone modification reader ZCWPW1 links histone methylation to PRDM9-induced double strand break repair
Huang, T.; Yuan, S.; Gao, L.; Li, M.; Yu, X.; Zhang, J.; Yin, Y.; Liu, C.; Zhang, C.; Lu, G.; Li, W.; Liu, J.; Chen, Z.-J.; Liu, H.
10.1101/836023 — developmental biology — Posted on 2020-05-05
4537 The histone modification reader ZCWPW1 links histone methylation to PRDM9-induced double strand break repair
Huang, T.; Yuan, S.; Gao, L.; Li, M.; Yu, X.; Zhang, J.; Yin, Y.; Liu, C.; Zhang, C.; Lu, G.; Li, W.; Liu, J.; Chen, Z.-J.; Liu, H.
10.1101/836023 — developmental biology — Posted on 2020-05-05
4538 A 'one-two punch' therapy strategy to target chemoresistance in estrogen receptor positive breast cancer
Chi, F.; Liu, J.; Brady, S. W.; Cosgrove, P. A.; Nath, A.; McQuerry, J. A.; Majumdar, S.; Moos, P. J.; Chang, J. T.; Kahn, M.; Bild, A. H.
10.1101/2020.03.12.989251 — cancer biology — Posted on 2020-05-05
4539 A 'one-two punch' therapy strategy to target chemoresistance in estrogen receptor positive breast cancer
Chi, F.; Liu, J.; Brady, S. W.; Cosgrove, P. A.; Nath, A.; McQuerry, J. A.; Majumdar, S.; Moos, P. J.; Chang, J. T.; Kahn, M.; Bild, A. H.
10.1101/2020.03.12.989251 — cancer biology — Posted on 2020-05-05
4540 Autoantibody landscape of advanced prostate cancer
Chen, W. S.; Haynes, W. A.; Waitz, R.; Kamath, K.; Vega-Crespo, A.; Shrestha, R.; Zhang, M.; Foye, A.; Baselga Carretero, I.; Garcilazo Perez, I.; Zhang, M.; Zhao, S. G.; Sjostrom, M.; Quigley, D. A.; Chou, J.; Beer, T.; Rettig, M.; Gleave, M.; Evans, C.; Lara, P.; Chi, K. N.; Reiter, R. E.; Alumkal, J. J.; Aggarwal, R.; Small, E. J.; Daugherty, P. S.; Ribas, A.; Oh, D. Y.; Shon, J. C.; Feng, F. Y.
10.1101/2020.05.02.074575 — cancer biology — Posted on 2020-05-05
4541 Autoantibody landscape of advanced prostate cancer
Chen, W. S.; Haynes, W. A.; Waitz, R.; Kamath, K.; Vega-Crespo, A.; Shrestha, R.; Zhang, M.; Foye, A.; Baselga Carretero, I.; Garcilazo Perez, I.; Zhang, M.; Zhao, S. G.; Sjostrom, M.; Quigley, D. A.; Chou, J.; Beer, T.; Rettig, M.; Gleave, M.; Evans, C.; Lara, P.; Chi, K. N.; Reiter, R. E.; Alumkal, J. J.; Aggarwal, R.; Small, E. J.; Daugherty, P. S.; Ribas, A.; Oh, D. Y.; Shon, J. C.; Feng, F. Y.
10.1101/2020.05.02.074575 — cancer biology — Posted on 2020-05-05
4544 Identifying cardiac actinin interactomes reveals sarcomere crosstalk with RNA-binding proteins
Ladha, F. A.; Thakar, K.; Pettinato, A. M.; Legere, N.; Cohn, R.; Romano, R.; Meredith, E.; Chen, Y.-s.; Hinson, J. T.
10.1101/2020.03.18.994004 — cell biology — Posted on 2020-05-05
4545 Rescoring ensembles of protein-protein docking poses using consensus approaches
Launay, G.; Ohue, M.; Prieto Santero, J.; Matsuzaki, Y.; Hilpert, C.; Uchikoga, N.; Hayashi, T.; Martin, J.
10.1101/2020.04.24.059469 — bioinformatics — Posted on 2020-05-05
4546 Tyrosine kinase inhibitors induce mitochondrial dysfunction during cardiomyocyte differentiation through alteration of GATA4-mediated networks
Liu, Q.; Wu, H.; Luo, Q.-J.; Jiang, C.; Duren, Z.; Van Bortle, K.; Zhao, M.-t.; Zhao, B.; Liu, J.; Marciano, D. P.; Lee-McMullen, B.; Zhu, C.; Narasimha, A. M.; Gruber, J. J.; Lipchik, A. M.; Guo, H.; Watson, N. K.; Tsai, M.-S.; Furihata, T.; Tian, L.; Wei, E.; Li, Y.; Steinmetz, L. M.; Wong, W. H.; Kay, M. A.; Wu, J. C.; Snyder, M. P.
10.1101/2020.05.04.077024 — systems biology — Posted on 2020-05-05
4547 Multiplexing information flow through dynamic signalling systems
Minas, G.; Woodcock, D. J.; Ashall, L.; Harper, C.; White, M. R. H.; Rand, D. A.
10.1101/863159 — systems biology — Posted on 2020-05-05
4548 The hepatic compensatory response to elevated systemic sulfide impairs medium chain fat oxidation and promotes diabetes
Carter, R. N.; Gibbins, M. T. G.; Barrios-Llerena, M. E.; Wilkie, S.; Freddolino, P.; Libiad, M.; Vitvitsky, V.; Emerson, B.; LeBihan, T.; Brice, M.; Su, H.; Denham, S.; Homer, N. Z. M.; Mc Fadden, C.; Tailleux, A.; Faresse, N.; Sulpice, T.; Briand, F.; Gillingwater, T.; Ahn, K. H.; Singha, S.; McMaster, C.; Hartley, R. C.; Staels, B.; Gray, G. A.; Finch, A.; Selman, C.; Banerjee, R.; Morton, N. M.
10.1101/2020.04.27.064287 — physiology — Posted on 2020-05-05
4550 A synthetic likelihood solution to the silent synapse estimation problem
Lynn, M. B.; Lee, K. F. H.; Soares, C.; Naud, R.; Beique, J.-C.
10.1101/781898 — neuroscience — Posted on 2020-05-05
4551 α-Synuclein aggregation intermediates form fibril polymorphs with distinct prion-like properties
Mehra, S.; Ahlawat, S.; Kumar, H.; Singh, N.; Navalkar, A.; Patel, K.; Kadu, P.; Kumar, R.; Jha, N. N.; Udgaonkar, J. B.; Agarwal, V.; Maji, S. K.
10.1101/2020.05.03.074765 — neuroscience — Posted on 2020-05-05
4553 Translatomic database of cortical astroglia across male and female mouse development reveals two distinct developmental phenotypes
Rurak, G. M.; Simard, S.; Charih, F.; Van Geel, A.; Stead, J.; Woodside, B.; Green, J. R.; Coppola, G.; Salmaso, N.
10.1101/681684 — neuroscience — Posted on 2020-05-05
4554 The CNS lymphatic system modulates the adaptive neuro-immune response in the perilesional cortex in a mouse model of traumatic brain injury
Wojciechowski, S.; Vihma, M.; Galbardi, B.; Keuters, M. H.; Antila, S.; Alitalo, K.; Koistinaho, J. E.; Noe, F. M.
10.1101/821645 — neuroscience — Posted on 2020-05-05
4555 A cortical wiring space links cellular architecture, funtional dynamics and hierarchies in humans
Paquola, C.; Seidlitz, J.; Benkarim, O.; Royer, J.; Klimes, P.; Bethlehem, R. A. I.; Lariviere, S.; Vos de Wael, R.; Hall, J.; Frauscher, B.; Smallwood, J.; Bernhardt, B.
10.1101/2020.01.08.899583 — neuroscience — Posted on 2020-05-05
4557 A broad response to intracellular long-chain polyphosphate in human cells
Bondy-Chorney, E.; Abramchuk, I.; Nasser, R.; Holinier, C.; Denoncourt, A.; Baijal, K.; McCarthy, L.; Khacho, M.; Lavallee-Adam, M.; Downey, M.
10.1101/2020.05.01.056192 — molecular biology — Posted on 2020-05-05
4558 Cutting in-line with iron: ribosomal function and non-oxidative RNA cleavage
Guth-Metzler, R.; Bray, M. S.; Frenkel-Pinter, M.; Suttapitugsakul, S.; Montllor-Albalate, C.; Bowman, J. C.; Wu, R.; Reddi, A. R.; Okafor, C. D.; Glass, J. B.; Williams, L. D.
10.1101/851097 — molecular biology — Posted on 2020-05-05
4559 RNA binding regulates TRIM25-mediated RIG-I ubiquitylation
Haubrich, K.; Augsten, S.; Simon, B.; Masiewicz, P.; Perez, K.; Lethier, M.; Rittinger, K.; Gabel, F.; Cusack, S.; Hennig, J.
10.1101/2020.05.04.070177 — molecular biology — Posted on 2020-05-05
4563 Global mapping of Salmonella enterica-host protein-protein interactions during infection
Walch, P. D. K.; Selkrig, J. P.; Knodler, L. A.; Rettel, M.; Stein, F.; Fernandez, K.; Vieitez, C.; Potel, C. M.; Scholzen, K.; Geyer, M.; Rottner, K.; Steele-Mortimer, O.; Savitski, M. M.; Holden, D. W.; Typas, A.
10.1101/2020.05.04.075937 — microbiology — Posted on 2020-05-05
4564 Circumpolar diversification of the Ixodes uriae tick virome
Pettersson, J. H.- O.; Ellstrom, P.; Ling, J.; Nilsson, I.; Bergstrom, S.; Gonzalez-Acuna, D.; Olsen, B.; Holmes, E. C.
10.1101/2020.05.04.075515 — microbiology — Posted on 2020-05-05
4567 Signatures of selection in the coral holobiont reveal complex adaptations to inshore environments driven by Holocene climate change
Cooke, I. R.; Ying, H.; Foret, S.; Bongaerts, P.; Strugnell, J. M.; Simakov, O.; Zhang, J.; Field, M. A.; Rodriguez-Lanetty, M.; Bell, S.; Bourne, D. G.; van Oppen, M.; Ragan, M. A.; Miller, D. J.
10.1101/2020.02.25.951905 — genomics — Posted on 2020-05-05
4568 Protein manipulation using single copies of short peptide tags in cultured cells and in Drosophila melanogaster
Vigano, M. A.; Ell, C.-M.; Kustermann, M. M.; Aguilar, G.; Matsuda, S.; Zhao, N.; Stasevich, T. J.; Pyrowolakis, G.; Affolter, M.
10.1101/2020.04.06.027599 — cell biology — Posted on 2020-05-05
4570 Genetic Background Dictates Aortic Fibrosis in Hypertensive Mice
Spronck, B.; Latorre, M.; Mehta, S.; Caulk, A. W.; Ramachandra, A. B.; Murtada, S.-I.; Rojas, A.; He, C.-S.; Jiang, B.; Wang, M.; Bersi, M. R.; Tellides, G.; Humphrey, J. D.
10.1101/727800 — bioengineering — Posted on 2020-05-05
4571 Causal associations between potentially modifiable risk factors and the Alzheimer's phenome: A Mendelian randomization study
Andrews, S. J.; Fulton-Howard, B.; O'Reilly, P.; Farrer, L. A.; Haines, J. L.; Mayeux, R.; Naj, A. C.; Pericak-Vance, M. A.; Schellenberg, G. D.; Wang, L.-S.; Marcora, E.; Goate, A. M.
10.1101/689752 — genetics — Posted on 2020-05-04
4574 PrimeDesign software for rapid and simplified design of prime editing guide RNAs
Hsu, J. Y.; Anzalone, A. V.; Grunewald, J.; Lam, K. C.; Shen, M. W.; Liu, D. R.; Joung, J. K.; Pinello, L.
10.1101/2020.05.04.077750 — bioinformatics — Posted on 2020-05-04
4576 Trapped Topoisomerase II initiates formation of de novo duplications via the nonhomologous end-joining pathway in yeast
Stantial, N.; Rogojina, A.; Gilbertson, M.; Sun, Y.; Miles, H.; Shaltz, S.; Berger, J.; Nitiss, K.; Jinks-Robertson, S.; Nitiss, J.
10.1101/2020.05.03.075358 — molecular biology — Posted on 2020-05-04
4579 Decomposition of transcriptional responses provides insights into differential antibiotic susceptibility
Sastry, A. V.; Dillon, N.; Poudel, S.; Hefner, Y.; Xu, S.; Szubin, R.; Feist, A.; Nizet, V.; Palsson, B.
10.1101/2020.05.04.077271 — microbiology — Posted on 2020-05-04
4581 Seasonal dynamics of methane cycling microbial communities in Amazonian floodplain sediments.
Gontijo, J. B.; Venturini, A. M.; Yoshiura, C. A.; Borges, C. D.; Moura, J. M. S.; Bohannan, B. J. M.; Nusslein, K.; Rodrigues, J. L. M.; Paula, F. S.; Tsai, S. M.
10.1101/2020.05.04.076356 — microbiology — Posted on 2020-05-04
4586 LAMA: Automated image analysis for developmentalphenotyping of mouse embryos
Horner, N. R.; Venkataraman, S.; Casero, R.; Brown, J. M.; Johnson, S.; Teboul, L.; Wells, S.; Brown, S. D. M.; Westerberg, H.; Mallon, A.-M.
10.1101/2020.05.04.075853 — bioinformatics — Posted on 2020-05-04
4588 Temporal signal and the phylodynamic threshold of SARS-CoV-2
Duchene, S.; Featherstone, L.; Haritopoulou-Sinanidou, M.; Rambaut, A.; Lemey, P.; Baele, G.
10.1101/2020.05.04.077735 — evolutionary biology — Posted on 2020-05-04
4589 Complexity in SARS-CoV-2 genome data: Price theory of mutant isolates
Mandal, S.; Singh, R. K. S.; Sharma, S. K.; Malik, M. Z.; Singh, R. K. B.
10.1101/2020.05.04.077511 — systems biology — Posted on 2020-05-04
4590 Genetic variation associated with PPO-inhibiting herbicide tolerance in sorghum
Adhikari, P.; Goodrich, E.; Fernandes, S. B.; Lipka, A. E.; Tranel, P.; Brown, P.; Jamann, T. M.
10.1101/2020.05.04.076620 — plant biology — Posted on 2020-05-04
4593 Tumor-specific changes in Kaposi sarcoma-associated herpesvirus genomes in Ugandan adults with Kaposi sarcoma
Santiago, C.; Goldman, J. D.; Zhao, H.; Pankow, A. P.; Okuku, F.; Schmitt, M. W.; Chen, L. H.; Hill, C. A.; Casper, C.; Phipps, W. T.; Mullins, J. I.
10.1101/2020.05.04.076638 — microbiology — Posted on 2020-05-04
4594 Hepatitis B virus Core protein nuclear interactome identifies SRSF10 as a host RNA-binding protein restricting HBV RNA production
Chabrolles, H.; Auclair, H.; Vegna, S.; Lahlali, T.; Pons, C.; Michelet, M.; Coute, Y.; Belmudes, L.; Kim, Y.; Di Bernardo, A.; Jalaguier, P.; Rivoire, M.; Arnold, L. D.; Lopatin, U.; Combet, C.; Zoulim, F.; Grierson, D.; Chabot, B.; Lucifora, J.; Durantel, D.; SALVETTI, A.
10.1101/2020.05.04.076646 — microbiology — Posted on 2020-05-04
4603 Circumstances and factors of sleep-related sudden infant deaths in Japan
Osawa, M.; Ueno, Y.; Ikeda, N.; Ikematsu, K.; Yamamoto, T.; Irie, W.; Kozawa, S.; Kotani, H.; Hamayasu, H.; Murase, T.; Shingu, K.; Sugimoto, M.; Nagao, R.; Kakimoto, Y.
10.1101/2020.05.04.076612 — pathology — Posted on 2020-05-04
4607 A genome-wide scan for candidate lethal variants in Thoroughbred horses.
Todd, E.; Thomson, P. C.; Hamilton, N. A.; Ang, R. A.; Lindgren, G.; Viklund, A.; Eriksson, S.; Mikko, S.; Strand, E.; Velie, B. D.
10.1101/2020.05.04.077008 — bioinformatics — Posted on 2020-05-04
4608 The UCSC SARS-CoV-2 Genome Browser
Fernandes, J. D.; Hinrichs, A. S.; Clawson, H.; Navarro Gonzales, J.; Lee, B. T.; Nassar, L. R.; Raney, B. J.; Rosenbloom, K. R.; Nerli, S.; Rao, A. A.; Schmelter, D.; Zweig, A. S.; Lowe, T. M.; Ares, M.; Corbett-Detig, R.; Kent, W. J.; Haussler, D.; Haeussler, M.
10.1101/2020.05.04.075945 — genomics — Posted on 2020-05-04
4609 Tacrolimus, but not voclosporin, inhibits insulin secretion from human islets at a clinical trough dose
Kolic, J.; Beet, L.; Overby, P.; Cen, H. H.; Panzhinskiy, E.; Ure, D. R.; Cross, J. L.; Huizinga, R. B.; Johnson, J. D.
10.1101/2020.04.30.071324 — cell biology — Posted on 2020-05-04
4613 ATP-driven separation of liquid phase condensates in bacteria
Guilhas, B.; Walter, J.-C.; Rech, J.; David, G.; Walliser, N.; Palmeri, J.; Mathieu-Demaziere, C.; Parmeggiani, A.; Bouet, J.-Y.; Le Gall, A.; Nollmann, M.
10.1101/791368 — cell biology — Posted on 2020-05-04
4614 Catalytic cleavage of HEAT and subsequent covalent binding of the tetralone moiety by the SARS-CoV-2 main protease
Günther, S.; Reinke, P. Y. A.; Oberthuer, D.; Yefanov, O.; Ginn, H.; Meier, S.; Lane, T. J.; Lorenzen, K.; Gelisio, L.; Brehm, W.; Dunkel, I.; Domaracky, M.; Saouane, S.; Lieske, J.; Ehrt, C.; Koua, F.; Tolstikova, A.; White, T. A.; Groessler, M.; Fleckenstein, H.; Trost, F.; Galchenkova, M.; Gevorkov, Y.; Li, C.; Awel, S.; Peck, A.; Xavier, P. L.; Barthelmess, M.; Schlünzen, F.; Werner, N.; Andaleeb, H.; Ullah, N.; Falke, S.; Franca, B. A.; Schwinzer, M.; Brognaro, H.; Seychell, B.; Gieseler, H.; Melo, D.; Zaitsev-Doyle, J. J.; Norton-Baker, B.; Knoska, J.; Esperanza, G.; Mashhour, A. R.; G
10.1101/2020.05.02.043554 — biophysics — Posted on 2020-05-04
4615 Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication
Vuong, W.; Khan, M. B.; Fischer, C.; Arutyunova, E.; Lamer, T.; Shields, J.; Saffran, H. A.; McKay, R. T.; van Belkum, M. J.; Joyce, M.; Young, H. S.; Tyrrell, D. L.; Vederas, J. C.; Lemieux, M. J.
10.1101/2020.05.03.073080 — biochemistry — Posted on 2020-05-04
4622 Gold Nanoparticles interacting with Synthetic Lipid Rafts: an AFM investigation
Ridolfi, A.; Caselli, L.; Montis, C.; Mangiapia, G.; Berti, D.; Brucale, M.; Valle, F.
10.1101/2020.05.03.075101 — biophysics — Posted on 2020-05-04
4627 Specific and conserved patterns of microbiota-structuring by maize benzoxazinoids in the field
Cadot, S.; Guan, H.; Bigalke, M.; Walser, J.-C.; Jander, G.; Erb, M.; van der Heijden, M.; Schlaeppi, K.
10.1101/2020.05.03.075135 — plant biology — Posted on 2020-05-04
4629 Criticality as a measure of developing proteinopathy in engineered human neural networks
Valderhaug, V. D.; Heiney, K.; Ramstad, O. H.; Braathen, G.; Kuan, W.-L.; Nichele, S.; Sandvig, A.; Sandvig, I.
10.1101/2020.05.03.074666 — neuroscience — Posted on 2020-05-04
4630 α-Synuclein aggregation intermediates form fibril polymorphs with distinct prion-like properties
Mehra, S.; Ahlawat, S.; Kumar, H.; Singh, N.; Navalkar, A.; Patel, K.; Kadu, P.; Kumar, R.; Jha, N. N.; Udgaonkar, J. B.; Agarwal, V.; Maji, S. K.
10.1101/2020.05.03.074765 — neuroscience — Posted on 2020-05-04
4635 Antagonistic Effects of Intraspecific Cooperation and Interspecific Competition on Thermal Performance
Tsai, H.-Y.; Rubenstein, D. R.; Chen, B.-F.; Liu, M.; Chan, S.-F.; Chen, D.-P.; Sun, S.-J.; Yuan, T.-N.; Shen, S.-F.
10.1101/2020.05.03.075325 — ecology — Posted on 2020-05-04
4636 Crystallographic and cryogenic electron microscopic structures and enzymatic characterization of sulfur oxygenase reductase from Sulfurisphaera tokodaii
Sato, Y.; Yabuki, T.; Adachi, N.; Moriya, T.; Arakawa, T.; Kawasaki, M.; Yamada, C.; Senda, T.; Fushinobu, S.; Wakagi, T.
10.1101/2020.05.03.074773 — biochemistry — Posted on 2020-05-04
4639 Gene capture by transposable elements leads to epigenetic conflict in maize
Muyle, A.; Seymour, D. K.; Darzentas, N.; Primetis, E.; Gaut, B. S.; Bousios, A.
10.1101/777037 — genomics — Posted on 2020-05-04
4643 Queuine is a nutritional regulator of Entamoeba histolytica response to oxidative stress and a virulence attenuator
Nagaraja, S.; Cai, M. W.; Sarid, L.; Shaulov, Y.; Trebicz-Geffen, M.; Mazumdar, M.; Varet, H.; Legendre, R.; Coppee, J.-Y.; Dedon, P. C.; Gourinath, S.; Guillen, N.; Saito-Nakano, Y.; Shimokawa, C.; Hisaeda, H.; Ankri, S.
10.1101/2020.04.30.070276 — microbiology — Posted on 2020-05-04
4644 High-content image-based drug screen identifies a clinical compound against cell transmission of adenovirus
Georgi, F.; Kuttler, F.; Murer, L.; Andriasyan, V.; Witte, R.; Yakimovich, A.; Turcatti, G.; Greber, U. F.
10.1101/2020.03.24.006346 — microbiology — Posted on 2020-05-04
4645 Transposable Elements activity and role in Meloidogyne incognita genome dynamic and adaptability
Kozlowski, D. K.; Hassanaly-Goulamhoussen, R.; Da-Rocha, M.; Bailly-Bechet, M.; Danchin, E. G.
10.1101/2020.04.30.069948 — evolutionary biology — Posted on 2020-05-04
4646 Trait-based responses to forestry and grazing modify long-term changes in biodiversity hot-spots of boreal forests
Happonen, K.; Muurinen, L.; Virtanen, R.; Kaakinen, E.; Grytnes, J.-A.; Kaarlejarvi, E.; Parisot, P.; Wolff, M.; Maliniemi, T.
10.1101/2020.04.30.069708 — ecology — Posted on 2020-05-04
4647 Base-pair resolution analysis of the effect of supercoiling on DNA flexibility and recognition
Pyne, A. L. B.; Noy, A.; Main, K.; Velasco-Berrelleza, V.; Piperakis, M. M.; Mitchenhall, L. A.; Cugliandolo, F. M.; Beton, J. G.; Stevenson, C. E. M.; Hoogenboom, B. W.; Bates, A. D.; Maxwell, A.; Harris, S. A.
10.1101/863423 — biophysics — Posted on 2020-05-04
4650 Trophic cascade driven by behavioural fine-tuning as naive prey rapidly adjust to a novel predator
Jolly, C. J.; Smart, A. S.; Moreen, J.; Webb, J. K.; Gillespie, G. R.; Phillips, B. L.
10.1101/856997 — ecology — Posted on 2020-05-04
4652 Phagocytic glia are obligatory intermediates in transmission of mutant huntingtin aggregates across neuronal synapses
Donnelly, K. M.; DeLorenzo, O. R.; Zaya, A. D. A.; Pisano, G. E.; Thu, W. M.; Luo, L.; Kopito, R. R.; Panning Pearce, M. M.
10.1101/868448 — neuroscience — Posted on 2020-05-04
4656 Different Proteins Mediate Step-wise Chromosome Architectures in Thermoplasma acidophilum and Pyrobaculum calidifontis
Maruyama, H.; Prieto, E. I.; Nambu, T.; Mashimo, C.; Kashiwagi, K.; Okinaga, T.; Atomi, H.; Takeyasu, K.
10.1101/2020.03.13.982959 — microbiology — Posted on 2020-05-04
4661 Antibiotics may influence gut microbiome signaling to the brain in preterm neonates
Russell, J. T.; Ruoss, J. L.; de la Cruz, D.; Li, N.; Bazacliu, C.; Patton, L.; Lobean McKinley, K.; Garrett, T. J.; Polin, R. A.; Triplett, E. W.; Neu, J.
10.1101/2020.04.20.052142 — microbiology — Posted on 2020-05-04
4663 A cortical wiring space linkss cellular architecture, funtional dynamics and hierarchicies in humans
Paquola, C.; Seidlitz, J.; Benkarim, O.; Royer, J.; Klimes, P.; Bethlehem, R. A. I.; Lariviere, S.; Vos de Wael, R.; Hall, J.; Frauscher, B.; Smallwood, J.; Bernhardt, B.
10.1101/2020.01.08.899583 — neuroscience — Posted on 2020-05-03
4665 Charting extracellular transcriptomes in The Human Biofluid RNA Atlas
Hulstaert, E.; Morlion, A.; Avila Cobos, F.; Verniers, K.; Nuytens, J.; Vanden Eynde, E.; Yigit, N.; Anckaert, J.; Geerts, A.; Hindryckx, P.; Jacques, P.; Brusselle, G.; Bracke, K. R.; Maes, T.; Malfait, T.; Derveaux, T.; Ninclaus, V.; Van Cauwenbergh, C.; Roelens, K.; Roets, E.; Hemelsoet, D.; Tilleman, K.; Brochez, L.; Kuersten, S.; Simon, L.; Karg, S.; Kautzky-Willers, A.; Leutner, M.; Nöhammer, C.; Slaby, O.; Willinge Prins, R.; Koster, J.; Lefever, S.; Schroth, G. P.; Vandesompele, J.; Mestdagh, P.
10.1101/823369 — genomics — Posted on 2020-05-04
4667 ORP5 Transfers Phosphatidylserine To Mitochondria And Regulates Mitochondrial Calcium Uptake At Endoplasmic Reticulum - Mitochondria Contact Sites
Rochin, L.; Sauvanet, C.; Jaaskelainen, E.; Houcine, A.; Arora, A.; Kivela, A. M.; Ma, X.; Marien, E.; Dehairs, J.; Le Bars, R.; Neveu, J.; Santonico, E.; Swinnen, J. V.; Bernard, D.; Tareste, D.; Olkkonen, V. M.; Giordano, F.
10.1101/695577 — cell biology — Posted on 2020-05-04
4668 A statistical framework for assessing pharmacological response and biomarkers with confidence
Wang, D.; Hensman, J.; Kutkaite, G.; Toh, T. S.; GDSC Screening Team, ; Dry, J. R.; Saez-Rodriguez, J.; Garnett, M.; Menden, M. P.; Dondelinger, F.
10.1101/2020.05.01.072983 — cancer biology — Posted on 2020-05-04
4673 Functional and genetic markers of niche partitioning among enigmatic members of the human oral microbiome
Shaiber, A.; Willis, A. D.; Delmont, T. O.; Roux, S.; Chen, L.-X.; Schmid, A. C.; Yousef, M.; Watson, A. R.; Lolans, K.; Esen, O. C.; Lee, S. T.; Downey, N.; Morrison, H. G.; Dewhirst, F.; Mark Welch, J. L.; Eren, A. M.
10.1101/2020.04.29.069278 — microbiology — Posted on 2020-05-03
4674 Hair follicle stem cell progeny heal blisters while pausing skin development
Fujimura, Y.; Watanabe, M.; Ohno, K.; Kobayashi, Y.; Takashima, S.; Nakamura, H.; Kosumi, H.; Wang, Y.; Mai, Y.; Lauria, A.; Proserpio, V.; Ujiie, H.; Iwata, H.; Nishie, W.; Nagayama, M.; Oliviero, S.; Donati, G.; Shimizu, H.; Natsuga, K.
10.1101/2020.04.08.032326 — cell biology — Posted on 2020-05-03
4678 PTENP1-AS contributes to BRAF inhibitor resistance and is associated with adverse clinical outcome in stage III melanoma
Vidarsdottir, L.; Azimi, A.; Sigvaldadottir, I.; Rahmanto, A. S.; Petri, A.; Kauppinen, S.; Ingvar, C.; Jonsson, G.; Olsson, H.; Frostvik-Stolt, M.; Tuominen, R.; Sangfelt, O.; Pokrovskaja, K.; Hansson, J.; Grander, D.; Egyhazi-Brage, s.; Johnsson, P.
10.1101/2020.05.03.073627 — cancer biology — Posted on 2020-05-03
4680 Large CRISPR-Cas-induced deletions in the oxamniquine resistance locus of the human parasite Schistosoma mansoni
Sankaranarayanan, G.; Coghlan, A.; Driguez, P.; Lotkowska, M. E.; Sanders, M.; Holroyd, N.; Tracey, A.; Berriman, M.; Rinaldi, G.
10.1101/2020.05.03.074831 — molecular biology — Posted on 2020-05-03
4682 Detection of pathogenic Leptospira in the environment and its association with antagonistic Pseudomonas spp. and rainy season
Vinod Kumar, K.; Lall, C.; Vimal Raj, R.; Vedhagiri, K.; Maile, A.; Muruganandam, N.; Sunish, I. P.; Vijayachari, P.
10.1101/2020.05.03.074963 — microbiology — Posted on 2020-05-03
4683 Spatiotemporal single-cell RNA sequencing of developing hearts reveals interplay between cellular differentiation and morphogenesis
Mantri, M.; Scuderi, G. J.; Nassab, R. A.; Wang, M. F. Z.; McKellar, D.; Butcher, J. T.; De Vlaminck, I.
10.1101/2020.05.03.065102 — genomics — Posted on 2020-05-03
4685 Large scale genomic analysis of 3067 SARS-CoV-2 genomes reveals a clonal geodistribution and a rich genetic variations of hotspots mutations
LAAMARTI, M.; ALOUANE, T.; KARTTI, S.; CHEMAO-ELFIHRI, M. W.; HAKMI, M.; ESSABBAR, A.; LAAMART, M.; HLALI, H.; ALLAM, L.; EL HAFIDI, N.; EL JAOUDI, R.; ALLALI, I.; MARCHOUDI, N.; FEKKAK, J.; BENRAHMA, H.; NEJJARI, C.; Amzazi, S.; BELYAMANI, L.; IBRAHIMI, A.
10.1101/2020.05.03.074567 — genomics — Posted on 2020-05-03
4689 Histopathological Landscape of Molecular Genetics and Clinical Determinants in MDS Patients
Bruck, O.; Lallukka-Bruck, S.; Hohtari, H.; Ianevski, A.; Ebeling, F.; Kovanen, P.; Kytola, S.; Aittokallio, T.; Marques, P. R.; Porkka, K.; Mustjoki, S.
10.1101/2020.05.03.073858 — bioinformatics — Posted on 2020-05-03
4692 A long non-coding RNA controls parasite differentiation in African trypanosomes
Guegan, F.; Bento, F.; Neves, D.; Sequeira, M.; Notredame, C.; Figueiredo, L. M.
10.1101/2020.05.03.074625 — microbiology — Posted on 2020-05-03
4698 Functional and Genetic Analysis of Viral Receptor ACE2 Orthologs Reveals a Broad Potential Host Range of SARS-CoV-2
Liu, Y.; Hu, G.; Wang, Y.; Zhao, X.; Ji, F.; Ren, W.; Gong, M.; Ju, X.; Li, C.; Hong, J.; Zhu, Y.; Cai, X.; Wu, J.; Lan, X.; Xie, Y.; Wang, X.; Yuan, Z.; Zhang, R.; Ding, Q.
10.1101/2020.04.22.046565 — microbiology — Posted on 2020-05-03
4699 Molecular Architecture of Early Dissemination and Evolution of the SARS-CoV-2 Virus in Metropolitan Houston, Texas
Long, S. W.; Olsen, R. J.; Christensen, P. A.; Bernard, D. W.; Davis, J. R.; Shukla, M.; Nguyen, M.; Saavedra, M. O.; Cantu, C. C.; Yerramilli, P.; Pruitt, L.; Subedi, S.; Hendrickson, H.; Eskandari, G.; Kumaraswami, M.; McLellan, J. S.; Musser, J. M.
10.1101/2020.05.01.072652 — genetics — Posted on 2020-05-03
4700 Regulated compartmentalization of enzymes in Golgi by GRASP55 controls cellular glycosphingolipid profile and function
Pothukuchi, P.; Agliarulo, I.; Pirozzi, M.; Rizzo, R.; Russo, D.; Turacchio, G.; Capolupo, L.; Hernandez-Corbacho, M. J.; Vanacore, G.; Dathan, N.; Henklein, P.; Nuchel, J.; Plomann, M.; Obeid, L. M.; Hannun, Y.; Luini, A.; D'Angelo, G.; Parashuraman, S.
10.1101/2020.05.03.074682 — cell biology — Posted on 2020-05-03
4703 Dropout in Neural Networks Simulates theParadoxical Effects of Deep Brain Stimulation onMemory
Tan, S. Z. K.; Du, R.; Perucho, J. A. U.; Chopra, S. S.; Vardhanabhut, V.; Lim, L. W.
10.1101/2020.05.01.073486 — neuroscience — Posted on 2020-05-03
4707 Analyses of spike protein from first deposited sequences of SARS-CoV2 from West Bengal, India
BEGUM, F.; MUKHERJEE, D.; THAKRIKI, D.; DAS, S.; TRIPATHI, P. P.; BANERJEE, A. K.; RAY, U.
10.1101/2020.04.28.066985 — molecular biology — Posted on 2020-05-03
4710 The TRF2 General Transcription Factor Is a Key Regulator of Cell Cycle Progression
Kedmi, A.; Sloutskin, A.; Epstein, N.; Gasri-Plotnitsky, L.; Ickowicz, D.; Shoval, I.; Doniger, T.; Darmon, E.; Ideses, D.; Porat, Z.; Yaron, O.; Juven-Gershon, T.
10.1101/2020.03.27.011288 — molecular biology — Posted on 2020-05-03
4711 In vivo inducible reverse genetics in patients' tumors to identify individual therapeutic targets
Carlet, M.; Voelse, K.; Vergalli, J.; Becker, M.; Herold, T.; Arner, A.; Liu, W.-H.; Dill, V.; Fehse, B.; Baldus, C. D.; Bastian, L.; Lenk, L.; Schewe, D. M.; Bagnoli, J. W.; Jost, P. J.; Miehting, C.; Riecken, K.; Schmidt-Supprian, M.; Binder, V.; Jeremias, I.
10.1101/2020.05.02.073577 — cancer biology — Posted on 2020-05-03
4712 Oral pyruvate prevents glaucomatous neurodegeneration
Williams, P. A.; Harder, J. M.; Guymer, C.; Wood, J. P.; Daskalakis, E.; Chidlow, G.; Cardozo, B. H.; Foxworth, N. E.; Cochran, K. E.; Ouellette, T. B.; Wheelock, C. E.; Casson, R. J.; John, S. W.
10.1101/2020.05.02.072215 — neuroscience — Posted on 2020-05-03
4713 Obesity-induced astrocyte dysregulation of heterosynaptic plasticity within the orbitofrontal cortex
Lau, B. K.; Murphy-Royal, C.; Kaur, M.; Qiao, M.; Gordon, G. R.; Bains, J. S.; Borgland, S. L.
10.1101/2020.05.01.073205 — neuroscience — Posted on 2020-05-03
4715 Low protein intake compromises the recovery of lactation-induced bone loss in female mouse dams without affecting skeletal muscles.
Kanakis, I.; Alameddine, M.; Scalabrin, M.; van 't Hof, R. J.; Liloglou, T.; Ozanne, S. E.; Goljanek-Whysall, K.; Vasilaki, A.
10.1101/2020.05.02.073759 — physiology — Posted on 2020-05-03
4717 Structure of the full kinetoplastids mitoribosome and insight on its large subunit maturation
Soufari, H.; Waltz, F.; Parrot, C.; Durrieu, S.; Bochler, A.; Kuhn, L.; Sissler, M.; Hashem, Y.
10.1101/2020.05.02.073890 — molecular biology — Posted on 2020-05-03
4718 Wnt-inducible Lrp6-APEX2 Interacting Proteins identify ESCRT Machinery and Trk-Fused Gene as Components of the Wnt Signaling Pathway
Colozza, G.; Jami-Alahmadi, Y.; Dsouza, A.; Tejeda-Munoz, N.; Albrecht, L. V.; Sosa, E.; Wohlschlegel, J. A.; De Robertis, E. M.
10.1101/2020.05.03.072579 — cell biology — Posted on 2020-05-03
4719 Short-term responses to ocean acidification: effects on relative abundance of eukaryotic plankton from the tropical Timor Sea
Rahlff, J.; Khodami, S.; Voskuhl, L.; Humphreys, M.; Stolle, C.; Martinez Arbizu, P.; Wurl, O.; Ribas-Ribas, M.
10.1101/2020.04.30.068601 — ecology — Posted on 2020-05-03
4720 Rab18 Binds PLIN2 and ACSL3 to Mediate Lipid Droplet Dynamics
Deng, Y.; Zhou, C.; Hammad, M. A.; Bamigbade, A. T.; Xu, S.; Zhang, S.; Liu, P.
10.1101/2020.05.02.073957 — cell biology — Posted on 2020-05-03
4722 Tcf21+ mesenchymal cells contribute to testis somatic cell development, homeostasis, and regeneration
Hammoud, S. S.; Shen, Y.-c.; LaRose, H.; Shami, A.; Moritz, L.; Manske, G. L.; Ma, Q.; Zheng, X.; Orwig, K.; Li, J.; Tallquist, M.
10.1101/2020.05.02.074518 — developmental biology — Posted on 2020-05-03
4723 Parkinson Disease-Linked Parkin Mediates Redox Reactions That Lower Oxidative Stress In Mammalian Brain
El Kodsi, D. N.; Tokarew, J. M.; Sengupta, R.; Lengacher, N. A.; Ng, A. C.; Boston, H.; Jiang, Q.; Palmberg, C.; Pileggi, C.; Shutinoski, B.; Li, J.; Nguyen, A. P.; Fehr, T. K.; Im, D. S.; Callaghan, S.; Park, D. S.; LaVoie, M. J.; Chan, J. A.; Takanashi, M.; Hattori, N.; Ratan, R. R.; Zecca, L.; Puente, L.; Shaw, G. S.; Harper, M.-E.; Holmgren, A.; Tomlinson, J. J.; Schlossmacher, M. G.
10.1101/2020.04.26.062380 — neuroscience — Posted on 2020-05-03
4724 Subthreshold repertoire and threshold dynamics of midbrain dopamine neuron firing in vivo
Otomo, K.; Perkins, J.; Kulkarni, A.; Stojanovic, S.; Roeper, J.; Paladini, C. A.
10.1101/2020.04.06.028829 — neuroscience — Posted on 2020-05-03
4725 XTRACT - Standardised protocols for automated tractography in the human and macaque brain
Warrington, S.; Bryant, K. L.; Khrapitchev, A. A.; Sallet, J.; Charquero-Ballester, M.; Douaud, G.; Jbabdi, S.; Mars, R. B.; Sotiropoulos, S. N.
10.1101/804641 — neuroscience — Posted on 2020-05-03
4726 Multi-modal characterization and simulation of human epileptic circuitry
Buchin, A.; de Frates, R.; Nandi, A.; Mann, R.; Chong, P.; Ng, L.; Miller, J.; Hodge, R. D.; Kalmbach, B.; Bose, S.; Rutishauser, U.; McConoughey, S.; Lein, E.; Berg, J.; Sorensen, S.; Gwinn, R.; Koch, C.; Ting, J. T.; Anastassiou, C. A.
10.1101/2020.04.24.060178 — neuroscience — Posted on 2020-05-03
4728 Regulation of dopamine-dependent transcription and cocaine action by Gadd45b
Zipperly, M. E.; Sultan, F. A.; Graham, G.-E.; Brane, A. C.; Simpkins, N. A.; Ianov, L.; Day, J. J.
10.1101/2020.05.01.072926 — neuroscience — Posted on 2020-05-03
4731 Mining ancient microbiomes using selective enrichment of damaged DNA molecules
Weiss, C. L.; Gansauge, M.-T.; Aximu-Petri, A.; Meyer, M.; Burbano, H. A.
10.1101/397927 — genomics — Posted on 2020-05-03
4734 Inside-out regulation of E-cadherin conformation and adhesion
Koirala, R.; Priest, A. V.; Yen, C.-F.; Cheah, J. S.; Gloerich, M.; Yamada, S.; Sivasankar, S.
10.1101/2020.05.02.074187 — biophysics — Posted on 2020-05-03
4735 Structural basis for control of antibiotic production by bacterial hormones
Zhou, S.; Bhukya, H.; Malet, N.; Harrison, P. J.; Rea, D.; Belousoff, M. J.; Venugopal, H.; Sydor, P. K.; Styles, K. M.; Song, L.; Cryle, M. J.; Alkhalaf, L. M.; Fülöp, V.; Challis, G. L.; Corre, C.
10.1101/2020.05.02.073981 — biochemistry — Posted on 2020-05-03
4740 Versatile live-cell activity analysis platform for characterization of neuronal dynamics at single-cell and network level
Yuan, X.; Schröter, M.; Obien, M. E. J.; Fiscella, M.; Gong, W.; Kikuchi, T.; Odawara, A.; Noji, S.; Suzuki, I.; Takahashi, J.; Hierlemann, A.; Frey, U.
10.1101/2020.05.01.071787 — neuroscience — Posted on 2020-05-03
4743 Myelin and nodal plasticity modulate action potential conduction in the adult mouse brain
Cullen, C. L.; Pepper, R. E.; Clutterbuck, M. T.; Pitman, K. A.; Oorschot, V.; Auderset, L.; Tang, A. D.; Ramm, G.; Emery, B.; Rodger, J.; Jolivet, R. B.; Young, K. M.
10.1101/726760 — neuroscience — Posted on 2020-05-03
4748 Quantifying uncertainty in brain-predicted age using scalar-on-image quantile regression
Palma, M.; Tavakoli, S.; Brettschneider, J.; Nichols, T. E.; for the Alzheimer's Disease Neuroimaging Initiative,
10.1101/853341 — neuroscience — Posted on 2020-05-03
4750 Multiethnic catalog of structural variants and their translational impact for disease phenotypes across 19,652 genomes
Sedlazeck, F. J.; Yu, B.; Mansfield, A. J.; Chen, H.; Krasheninina, O.; Tin, A.; Qi, Q.; Zarate, S.; Traynelis, J.; Menon, V.; BCM HGSC Sequencing Lab, ; Hu, J.; doddapaneni, h. v.; Metcalf, G.; Coresh, J.; Kaplan, R.; muzny, d. m.; Jun, G.; Gibbs, R. A.; Salerno, W.; Boerwinkle, E.
10.1101/2020.05.02.074096 — genomics — Posted on 2020-05-03
4751 Single nucleus and in situ RNA sequencing reveals cell topographies in the human pancreas
Tosti, L.; Hang, Y.; Debnath, O.; Tiesmeyer, S.; Trefzer, T.; Steiger, K.; Ten, F. W.; Lukassen, S.; Ballke, S.; Kuehl, A. A.; Spieckermann, S.; Bottino, R.; Ishaque, N.; Weichert, W.; Kim, S. K.; Eils, R.; Conrad, C.
10.1101/733964 — genomics — Posted on 2020-05-03
4755 Autoantibody landscape of advanced prostate cancer
Chen, W. S.; Haynes, W. A.; Waitz, R.; Kamath, K.; Vega-Crespo, A.; Shrestha, R.; Foye, A.; Baselga Carretero, I.; Zhang, M.; Zhao, S. G.; Sjostrom, M.; Quigley, D. A.; Chou, J.; Beer, T.; Rettig, M.; Gleave, M.; Evans, C.; Lara, P.; Chi, K. N.; Reiter, R. E.; Alumkal, J. J.; Aggarwal, R.; Small, E. J.; Daugherty, P. S.; Ribas, A.; Oh, D. Y.; Shon, J. C.; Feng, F. Y.
10.1101/2020.05.02.074575 — cancer biology — Posted on 2020-05-03
4759 Spatio-temporal analyses of OCT4 expression and fate transitions in human embryonic stem cells
Orozco-Fuentes, S.; Wadkin, L. E.; Neganova, I.; Lako, M.; Barrio, R. A.; Baggaley, A. W.; Shukurov, A.; Parker, N. G.
10.1101/2020.05.02.074435 — biophysics — Posted on 2020-05-03
4760 No evidence for transient transformation via pollen magnetofection in several monocot species
Vejlupkova, Z. E.; Warman, C.; Sharma, R.; Scheller, H.; Mortimer, J.; Fowler, J. E.
10.1101/2020.05.01.071266 — plant biology — Posted on 2020-05-03
4762 Optically splitting symmetric neuron pairs in C. elegans
Davis, L.; Radman, I.; Goutou, A.; Tynan, A.; Baxter, K.; Xi, Z.; Chin, J. W.; Greiss, S.
10.1101/2020.05.02.072363 — neuroscience — Posted on 2020-05-03
4765 Synaptic and intrinsic mechanisms underlying development of cortical direction selectivity
Roy, A.; Osik, J. J.; Meschede-Krasa, B.; Alford, W.; Leman, D. P.; Van Hooser, S. D.
10.1101/776534 — neuroscience — Posted on 2020-05-03
4767 One gene, multiple ecological strategies: a biofilm regulator is a capacitor for sustainable diversity
Mhatre, E. R.; Snyder, D. J.; Sileo, E.; Turner, C. B.; Buskirk, S. W.; Fernandez, N. L.; Neiditch, M. B.; Waters, C. M.; Cooper, V. S.
10.1101/2020.05.02.074534 — microbiology — Posted on 2020-05-03
4768 Sleep Deficits and Cannabis Use Behaviors: An Analysis of Shared Genetics Using Linkage Disequilibrium Score Regression and Polygenic Risk Prediction
Winiger, E. A.; Ellingson, J. M.; Morrison, C. L.; Corley, R. P.; Pasman, J. A.; Wall, T. L.; Hopfer, C. J.; Hewitt, J. K.
10.1101/2020.05.02.053983 — genetics — Posted on 2020-05-03
4770 The mitotic protein NuMA plays a spindle-independent role in nuclear formation and mechanics
Serra-Marques, A.; Houtekamer, R.; Hintzen, D.; Canty, J. T.; Yildiz, A.; Dumont, S.
10.1101/2020.05.02.070680 — cell biology — Posted on 2020-05-03
4771 Impact of sustained TGFβ receptor inhibition on chromatin accessibility and gene expression in cultured human endometrial MSC
Lucciola, R.; Vrljicak, P.; Filby, C.; Darzi, S.; Gurung, S.; Muter, J.; Ott, S.; Brosens, J.; Gargett, C. E.
10.1101/2020.05.01.073346 — cell biology — Posted on 2020-05-03
4772 Novel cytokinetic ring components drive negative feedback in cortical contractility
Rehain-Bell, K.; Werner, M. E.; Doshi, A.; Cortes, D. B.; Sattler, A.; Vuong-Brender, T. T.; Labouesse, M.; Maddox, A. S.
10.1101/633743 — cell biology — Posted on 2020-05-03
4776 Revealing the high propensity of RNAs to non-specifically bind drug-like small molecules
Kelly, M. L.; Chu, C.-C.; Shi, H.; Ganser, L. R.; Bogerd, H. P.; Huynh, K.; Hou, Y.; Cullen, B. R.; Al-Hashimi, H. M.
10.1101/2020.05.02.074336 — biochemistry — Posted on 2020-05-03
4779 The M1/M4 agonist xanomeline modulates functional connectivity and NMDAR antagonist-induced changes in the mouse brain
Montani, C.; Canella, C.; Schwarz, A. J.; Li, J.; Gilmour, G.; Galbusera, A.; Wafford, K. A.; McCarthy, A. P.; Shaw, D. B.; Knitowski, K.; McKinzie, D.; Gozzi, A.; Felder, C.
10.1101/2020.05.01.072595 — neuroscience — Posted on 2020-05-03
4780 Identification of palmitoyl protein thioesterase 1 substrates defines roles for synaptic depalmitoylation
Gorenberg, E. L.; Zhao, H. R.; Bishai, J.; Chou, V.; Wirak, G. S.; Lam, T. T.; Chandra, S. S.
10.1101/2020.05.02.074302 — neuroscience — Posted on 2020-05-03
4782 The microbiota promotes social behavior by neuro-immune modulation of neurite complexity
Bruckner, J. J.; Stednitz, S. J.; Grice, M. Z.; Larsch, J. J.; Tallafuss, A.; Washbourne, P.; Eisen, J.
10.1101/2020.05.01.071373 — neuroscience — Posted on 2020-05-03
4785 Gliding motility of Plasmodium merozoites
Yahata, K.; Hart, M. N.; Davies, H.; Asada, M.; Templeton, T. J.; Treeck, M.; Moon, R. W.; Kaneko, O.
10.1101/2020.05.01.072637 — microbiology — Posted on 2020-05-03
4787 LINE-1 DNA methylation in response to aging and vitamin D
Ong, L.; Schibeci, S.; Fewings, N.; Booth, D.; Parnell, G.
10.1101/2020.05.02.073551 — genetics — Posted on 2020-05-03
4789 A statistical framework for assessing pharmacological response and biomarkers with confidence
Wang, D.; Hensman, J.; Kukaite, G.; Toh, T. S.; GDSC Screening Team, ; Dry, J. R.; Saez-Rodriguez, J.; Garnett, M.; Menden, M. P.; Dondelinger, F.
10.1101/2020.05.01.072983 — cancer biology — Posted on 2020-05-03
4796 Inferring Maps of Cellular Structures from MRI Signals using Deep Learning
Liang, Z.; Lee, C. H.; Arefin, T. M.; Dong, Z.; Walczak, P.; Shi, S.-H.; Knoll, F.; Ge, Y.; Ying, L.; Zhang, J.
10.1101/2020.05.01.072561 — bioengineering — Posted on 2020-05-03
4797 Robust Sequence Determinants of α-Synuclein Toxicity in Yeast Implicate Membrane Binding
Newberry, R. W.; Arhar, T.; Costello, J.; Hartoularos, G. C.; Maxwell, A. M.; Naing, Z. Z. C.; Pittman, M.; Reddy, N. R.; Schwarz, D. M. C.; Wassarman, D. R.; Wu, T. S.; Barrero, D.; Caggiano, C.; Catching, A.; Cavazos, T. B.; Estes, L. S.; Faust, B.; Fink, E. A.; Goldman, M. A.; Gomez, Y. K.; Gordon, M. G.; Gunsalus, L. M.; Hoppe, N.; Jaime-Garza, M.; Johnson, M. C.; Jones, M. G.; Kung, A. F.; Lopez, K. E.; Lumpe, J.; Martyn, C.; McCarthy, E. E.; Miller-Vedam, L. E.; Navarro, E. J.; Palar, A.; Pellegrino, J.; Saylor, W.; Stephens, C. A.; Strickland, J.; Torosyan, H.; Wankowicz, S. A.; Wong, D
10.1101/2020.05.01.072884 — biochemistry — Posted on 2020-05-03
4798 Arabidopsis SMN2/HEN2, encoding DEAD-box RNA helicase, governs proper expression of the resistance gene SMN1/RPS6 and is involved in dwarf, autoimmune phenotypes of mekk1 and mpk4
Takagi, M.; Iwamoto, N.; Kubo, Y.; Morimoto, T.; Takagi, H.; Takahashi, F.; Nishiuchi, T.; Tanaka, K.; Taji, T.; Kaminaka, H.; Shinozaki, K.; Akimitsu, K.; Terauchi, R.; Shirasu, K.; Ichimura, K.
10.1101/2020.05.01.071647 — plant biology — Posted on 2020-05-03
4801 LSD flattens the functional hierarchy of the human brain
Girn, M.; Roseman, L.; Bernhardt, B.; Smallwood, J.; Carhart-Harris, R. L.; Spreng, N.
10.1101/2020.05.01.072314 — neuroscience — Posted on 2020-05-03
4803 An altered cognitive strategy associated with reduction of synaptic inhibition in the prefrontal cortex after social play deprivation in rats
Omrani, A.; Bijlsma, A.; Spoelder, M.; Verharen, J. P. H.; Bauer, L.; Cornelis, C.; van Dorland, R.; Vanderschuren, L. J. M. J.; Wierenga, C. J.
10.1101/2020.05.01.070540 — neuroscience — Posted on 2020-05-03
4806 Integrative genomic analysis in African American children with asthma finds 3 novel loci associated with lung function
Goddard, P. C.; Keys, K. L.; Mak, A. C. Y.; Lee, E. Y.; Liu, A. K.; Samedy-Bates, L.-A.; Risse-Adams, O.; Contreras, M. G.; Elhawary, J. R.; Hu, D.; Huntsman, S.; Oh, S. S.; Salazar, S.; Eng, C.; Himes, B. E.; White, M. J.; Burchard, E. G.
10.1101/2020.05.01.045468 — genetics — Posted on 2020-05-03
4808 The importomer is a peroxisomal membrane protein translocase
Martenson, J. S.; Tam, H.; McQuown, A. J.; Reif, D.; Zhou, J.; Denic, V.
10.1101/2020.05.01.072660 — cell biology — Posted on 2020-05-03
4814 Kaleidoscope: A New Bioinformatics Pipeline Web Application for In Silico Hypothesis Exploration of Omics Signatures
Alganem, K.; Shukla, R.; Eby, H.; Abel, M.; Zhang, X.; Mcintyre, W. B.; Lee, J.; Au-Yeung, C.; Asgariroozbehani, R.; Panda, R.; O'Donovan, S. M.; Funk, A.; Hahn, M.; Meller, J.; McCullumsmith, R.
10.1101/2020.05.01.070805 — bioinformatics — Posted on 2020-05-03
4816 Deep learning enables the atomic structure determination of the Fanconi Anemia core complex from cryoEM
Farrell, D.; Anishchanka, I.; Shakeel, S.; Lauko, A.; Passmore, L. A.; Baker, D.; DiMaio, F.
10.1101/2020.05.01.072751 — biochemistry — Posted on 2020-05-03
4817 A New Framework for MR Diffusion Tensor Distribution
Magdoom, K. N.; Pajevic, S.; Gasbarra, D.; Basser, P. J.
10.1101/2020.05.01.071118 — neuroscience — Posted on 2020-05-02
4820 A broad response to intracellular long-chain polyphosphate in human cells
Bondy-Chorney, E.; Abramchuk, I.; Nasser, R.; Holinier, C.; Denoncourt, A.; Baijal, K.; McCarthy, L.; Khacho, M.; Lavallee-Adam, M.; Downey, M.
10.1101/2020.05.01.056192 — molecular biology — Posted on 2020-05-03
4822 Epithelial Cell Regulation of Type 2 Cytokine Release by Peripheral Blood Mononuclear Cells
Southern, A.; Gondrand, A.; Layzell, S.; Cane, J. L.; Pavord, I. D.; Powell, T. J.
10.1101/2020.05.01.067694 — immunology — Posted on 2020-05-03
4824 Long-TUC-seq is a robust method for quantification of metabolically labeled full-length isoforms
Rahmanian, S.; Balderrama-Gutierrez, G.; Wyman, D.; McGill, C. J.; Nguyen, K.; Spitale, R.; Mortazavi, A.
10.1101/2020.05.01.073296 — genomics — Posted on 2020-05-02
4825 DNA methylation covariation in human whole blood and sperm: implications for studies of intergenerational epigenetic effects
Asenius, F.; Gorrie-Stone, T. J.; Brew, A.; Panchbhaya, Y.; Williamson, E.; Schalkwyk, L. C.; Rakyan, V.; Holland, M. L.; Marzi, S. J.; Williams, D. J.
10.1101/2020.05.01.072934 — genomics — Posted on 2020-05-02
4826 Reference genome for the highly transformable Setaria viridis cultivar ME034V
Thielen, P. M.; Pendelton, A. L.; Player, R. A.; Bowden, K. V.; Lawton, T. J.; Wisecaver, J. H.
10.1101/2020.05.02.073684 — genomics — Posted on 2020-05-03
4832 Velcro-like mannose and slime-like sialic acid interactions guide self- adhesion and aggregation of virus N-glycan shields
Ogharandunkun, E.; Tewolde, W.; Damtae, E.; Wang, S.; Ivanov, A.; Kumari, N.; Nekhai, S.; Chandran, P.
10.1101/2020.05.01.072769 — biophysics — Posted on 2020-05-02
4840 Transcriptomic expression patterns of two contrasting lowland rice varieties reveal high iron stress tolerance
Kar, S.; Mai, H.-J.; Khalouf, H.; Ben Abdallah, H.; Flachbart, S.; Fink-Straube, C.; Braeutigam, A.; Xiong, G.; Shang, L.; Panda, S. K.; Bauer, P.
10.1101/2020.05.01.070516 — plant biology — Posted on 2020-05-02
4844 Impact of long- and short-range fiber depletion on the cognitive deficits of fronto-temporal dementia
Savard, M.; Pascoal, T.; Dhollander, T.; Iturria-Medina, Y.; Vitali, P.; Therriault, J.; Mathotaarachchi, S.; Benedet, A. L.; Gauthier, S.; Rosa Neto, P.
10.1101/2020.05.01.064576 — neuroscience — Posted on 2020-05-02
4845 Structural and functional alterations associated with the LRRK2 G2019S mutation revealed in structured human neural networks
Valderhaug, V. D.; Ramstad, O. H.; van de Wijdeven, R.; Heiney, K.; Nichele, S.; Sandvig, A.; Sandvig, I.
10.1101/2020.05.02.073726 — neuroscience — Posted on 2020-05-02
4848 Equine synovial fluid small non-coding RNA signatures in early osteoarthritis
Castanheira, C.; Balaskas, P.; Falls, C.; Ashraf-Kharaz, Y.; Clegg, P. D.; Burke, K.; Fang, Y.; Dyer, P.; Welting, T. J.; Peffers, M. J.
10.1101/2020.05.01.066027 — molecular biology — Posted on 2020-05-02
4856 ATP driven diffusiophoresis: active cargo transport without motor proteins
Ramm, B.; Goychuk, A.; Khmelinskaia, A.; Blumhardt, P.; Ganzinger, K. A.; Frey, E.; Schwille, P.
10.1101/2020.05.01.072744 — biophysics — Posted on 2020-05-02
4858 Structural and molecular determinants of CCS-mediated copper activation of MEK1/2
Grasso, M.; Bond, G. J.; Kim, Y.-J.; Alwan, K. B.; Boyd, S.; Dzebo, M. M.; Valenzuela, S.; Tsang, T.; Schibrowsky, N. A.; Matthews, M. L.; Burslem, G. M.; Wittung-Stafshede, P.; Winkler, D. D.; Blackburn, N. J.; Marmorstein, R.; Brady, D. C.
10.1101/2020.05.01.072124 — biochemistry — Posted on 2020-05-02
4859 Structural and Functional Implications of Non-synonymous Mutations in the Spike protein of 2,954 SARS-CoV-2 Genomes
Nelson-Sathi, S.; Perunthottathu K, U.; Easwaran, S.; Nair, R. R.; Joseph, I.; Nori, S. R. C.; Philip, J. S.; Prasad, R.; Kolaparamba, K. V.; Ramesh, S.; Pillai, H.; Gosh, S.; TR, S. K.; Pillai, M. R.
10.1101/2020.05.02.071811 — evolutionary biology — Posted on 2020-05-02
4860 An artificial intelligence system reveals liquiritin inhibits SARS-CoV-2 by mimicking type I interferon
Zhu, J.; Deng, Y.-Q.; Wang, X.; Li, X.-F.; Zhang, N.-N.; Liu, Z.; Zhang, B.; Qin, C.; Xie, Z.
10.1101/2020.05.02.074021 — systems biology — Posted on 2020-05-02
4861 PSGL-1 blocks SARS-CoV-2 S protein-mediated virus attachment and infection of target cells
He, S.; Hetrick, B.; Dabbagh, D.; Akhrymuk, I. V.; Kehn-Hall, K.; Freed, E. O.; Wu, Y.
10.1101/2020.05.01.073387 — microbiology — Posted on 2020-05-02
4864 Rapid adaptation of SARS-CoV-2 in BALB/c mice: Novel mouse model for vaccine efficacy
Gu, H.; Chen, Q.; Yang, G.; He, L.; Fan, H.; Deng, Y.-q.; Wang, Y.; Teng, Y.; Zhao, Z.; Cui, Y.; Li, Y.; Li, X.-F.; Li, J.; Zhang, N.; Yang, X.; Chen, S.; Zhao, G.; Wang, X.; Luo, D.; Wang, H.; Yang, X.; Li, Y.; Han, G.; He, Y.; Zhou, X.; Geng, S.; Sheng, X.; Shi, B.; Sun, S.; Qin, C.-F.; Zhou, Y.
10.1101/2020.05.02.073411 — microbiology — Posted on 2020-05-02
4865 Identification of Drugs Blocking SARS-CoV-2 Infection using Human Pluripotent Stem Cell-derived Colonic Organoids
Duan, X.; Han, Y.; Yang, L.; Nilsson, B.; Wang, P.; Zhang, T.; Wang, X.; Xu, D.; Xiang, J. Z.; uhl, s.; Huang, Y.; Chen, H.; Wang, H.; tenOever, B. R.; Schwartz, R. E.; Ho, D. D.; Pan, F. C.; Chen, S.; Evans, T. R.
10.1101/2020.05.02.073320 — microbiology — Posted on 2020-05-02
4867 Mutually opposing activity of PIN7 splicing isoforms is required for auxin-mediated tropic responses in Arabidopsis thaliana
Kashkan, I.; Hrtyan, M.; Filepova, R.; Vondrakova, Z.; Hejatko, J.; Simon, S.; Rombaut, D.; Jacobs, T. B.; Frilander, M. J.; Friml, J.; Petrasek, J.; Ruzicka, K.
10.1101/2020.05.02.074070 — plant biology — Posted on 2020-05-02
4871 Illuminating chromatin compaction in live cells and fixed tissues using SiR-DNA fluorescence lifetime
Hockings, C.; Poudel, C.; Feeney, K. A.; Novo, C. L.; Hamouda, M. S.; Mela, I.; Fernandez-Antoran, D.; Vallejo Ramirez, P. P.; Rugg-Gunn, P.; Chalut, K.; Kaminski, C. F.; Kaminski Schierle, G. S.
10.1101/2020.05.02.073536 — cell biology — Posted on 2020-05-02
4875 Regulation of bacterial cell cycle progression by redundant phosphatases
Coppine, J.; Kaczmarczyk, A.; Petit, K.; Brochier, T.; Jenal, U.; Hallez, R.
10.1101/2020.04.29.069633 — microbiology — Posted on 2020-05-02
4877 Altered substance P signaling underlies perivascular sensory nerve dysfunction in inflammatory bowel disease
Norton, C. E.; Grunz-Borgmann, E. A.; Hart, M.; Jones, B. W.; Franklin, C. M.; Boerman, E. M.
10.1101/2020.04.29.066126 — physiology — Posted on 2020-05-02
4878 Synergistic Material-Topography Combinations to Achieve Immunomodulatory Osteogenic Biomaterials
Burroughs, L.; Amer, M.; Vassey, M.; Koch, B.; Figueredo, G.; Mukonoweshuro, B.; Mikulskis, P.; Vasilevich, A.; Vermeulen, S.; Dryden, I. L.; Winkler, D. A.; Ghaemmaghami, A. M.; Rose, F. R. A. J.; de Boer, J.; Alexander, M. R.
10.1101/2020.04.29.067421 — bioengineering — Posted on 2020-05-02
4879 LFA-1 signals to promote actin polymerization and upstream migration in T cells
Roy, N. H.; Kim, S. H.; Buffone, A.; Blumenthal, D.; Huang, B.; Agarwal, S.; Schwartzberg, P. L.; Hammer, D. A.; Burkhardt, J. K.
10.1101/2020.04.29.069302 — cell biology — Posted on 2020-05-02
4883 S100A8/A9 mediate the reprograming of normal mammary epithelial cells induced by dynamic cell-cell interactions with adjacent breast cancer cells.
Jo, S. H.; Heo, W. H.; Quan, M.; Hong, B. S.; Kim, J. H.; Lee, H.-B.; Han, W.; Park, Y.; Lee, D.-S.; Kwon, N. H.; Park, M. C.; Chae, J.; Kim, J.-I.; Noh, D.-Y.; Moon, H.-G.
10.1101/312884 — cancer biology — Posted on 2020-05-02
4884 Inflated citations and metrics of journals discontinued from Scopus for publication concerns: the GhoS(t)copus Project
Cortegiani, A.; Ippolito, M.; Ingoglia, G.; Manca, A.; Cugusi, L.; Severin, A.; Strinzel, M.; Panzarella, V.; Campisi, G.; Lalu, M.; Gregoretti, C.; Einav, S.; Moher, D.; Giarratano, A.
10.1101/2020.03.26.007435 — scientific communication and education — Posted on 2020-05-02
4887 Determination of primary microRNA processing in clinicalsamples by targeted pri-miR-sequencing
Conrad, T.; Ntini, E.; Lang, B.; Cozzuto, L.; Andersen, J. B.; Marquardt, J. U.; Ponomarenko, J.; Tartaglia, G. G.; Vang Orom, U. A.
10.1101/2020.04.30.070912 — molecular biology — Posted on 2020-05-02
4888 Novel Loss-of-Function Mutations in COCH Cause Autosomal Recessive Nonsyndromic Deafness
Booth, K. T.; Ghaffar, A.; Rashid, M.; Hovey, L. T.; Hussain, M.; Frees, K.; Renkes, E. M.; Nishimura, C. J.; Shahzad, M.; Smith, R. J. H.; Ahmed, Z.; Azaiez, H.; Riazuddin, S.
10.1101/2020.04.30.071134 — genetics — Posted on 2020-05-02
4889 Genetic, morphological, and niche variation in the widely hybridizing Rhus integrifolia-Rhus ovata species complex.
Barrett, C. F.; Lambert, J.; Santee, M. V.; Sinn, B. T.; Skibicki, S. V.; Stephens, H. M.; Thixton, H.
10.1101/2020.04.30.070813 — evolutionary biology — Posted on 2020-05-02
4891 Platinum-Induced Ubiquitination of Phosphorylated H2AX by RING1A is Mediated by Replication Protein A in Ovarian Cancer
Sriramkumar, S.; Matthews, T. D.; Ghobashi, A. H.; Miller, S. A.; VanderVere-Carozza, P. S.; Pawelczak, K. S.; Nephew, K. P.; Turchi, J. J.; O'Hagan, H. M.
10.1101/2020.04.30.070185 — cancer biology — Posted on 2020-05-02
4894 Comparing proportional and ordinal dominance ranks reveals multiple competitive landscapes in an animal society
Levy, E. J.; Zipple, M. N.; McLean, E.; Campos, F. A.; Dasari, M.; Fogel, A. S.; Franz, M.; Gesquiere, L. R.; Gordon, J. B.; Grieneisen, L.; Habig, B.; Jansen, D. J.; Learn, N. H.; Weibel, C. J.; Alberts, S. C.; Archie, E. A.; Altmann, J.
10.1101/2020.04.30.065805 — animal behavior and cognition — Posted on 2020-05-02
4898 Leveraging Tools from Autonomous Navigation for Rapid, Robust Neuron Connectivity
Drenkow, N.; Joyce, J.; Matelsky, J.; Larabi, R.; Heiko, J.; Kleissas, D.; Wester, B.; Johnson, E. C.; Gray-Roncal, W. R.
10.1101/2020.04.30.070755 — neuroscience — Posted on 2020-05-02
4899 Causal role for sleep-dependent reactivation of learning-activated sensory ensembles for fear memory consolidation
Clawson, B.; Pickup, E.; Ensing, A.; Geneseo, L.; Shaver, J.; Gonzalez-Amoretti, J.; Zhao, M.; York, A. K.; Jiang, S.; Aton, S.
10.1101/2020.04.30.070466 — neuroscience — Posted on 2020-05-02
4900 Poly(2-oxazoline) nanoparticle delivery enhances the therapeutic potential of vismodegib for medulloblastoma by improving CNS pharmacokinetics and reducing systemic toxicity
Hwang, D.; Dismuke, T.; Tikunov, A.; Rosen, E.; Kagel, J.; Ramsey, J.; Lim, C.; Zamboni, W.; Kabanov, A.; Gershon, T. R.; Sokolsky-Papkov, M.
10.1101/2020.04.30.068726 — neuroscience — Posted on 2020-05-02
4901 A Novel Efficient L-Lysine Exporter Identified by Functional Metagenomics
Malla, S.; Helm, E. v. d.; Darbani, B.; Wieschalka, S.; Forster, J.; Borodina, I.; Sommer, M. O. A.
10.1101/2020.04.30.071142 — molecular biology — Posted on 2020-05-02
4902 Longevity, clonal relationship and transcriptional program of celiac disease-specific plasma cells
Lindeman, I.; Zhou, C.; Eggesbo, L. M.; Miao, Z.; Polak, J.; Lundin, K. E.; Jahnsen, J.; Qiao, S.-W.; Iversen, R.; Sollid, L. M.
10.1101/2020.04.30.058560 — immunology — Posted on 2020-05-02
4903 Genome mapping resolves structural variation within segmental duplications associated with microdeletion/microduplication syndromes
Mostovoy, Y.; Yilmaz, F.; Chow, S. K.; Chu, C.; Lin, C.; Geiger, E. A.; Meeks, N. J. L.; Chatfield, K. C.; Coughlin, C. R.; Kwok, P.-Y.; Shaikh, T. H.
10.1101/2020.04.30.071449 — genomics — Posted on 2020-05-02
4904 Short-term responses to ocean acidification: effects on relative abundance of eukaryotic plankton from the tropical Timor Sea
Rahlff, J.; Khodami, S.; Voskuhl, L.; Humphreys, M.; Stolle, C.; Martinez Arbizu, P.; Wurl, O.; Ribas-Ribas, M.
10.1101/2020.04.30.068601 — ecology — Posted on 2020-05-02
4906 Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in Myc-driven Medulloblastoma
Veo, B. L.; Danis, E.; Pierce, A.; Wang, D.; Fosmire, S.; Sullivan, K. D.; Joshi, M.; Khanal, S.; Dahl, N.; Karam, S.; Serkova, N.; Venkataraman, S.; Vibhakar, R.
10.1101/2020.04.30.069237 — cancer biology — Posted on 2020-05-02
4907 An Arf/Rab cascade controls the growth and invasiveness of glioblastoma
Kulasekaran, G.; Chaineau, M.; Piscapo, V. E.; Verginelli, F.; Girard, M.; Fotouhi, M.; Tang, Y.; Dali, R.; Lo, R.; Stifani, S.; McPherson, P. S.
10.1101/2020.04.30.070334 — cancer biology — Posted on 2020-05-02
4912 Human and mouse transcriptome profiling identifies cross-species homology in pulmonary and lymph node mononuclear phagocytes
Leach, S.; Gibbings, S.; Tewari, A.; Atif, S.; Vestal, B.; Danhorn, T.; Janssen, W.; Wager, T.; Jakubzick, C.
10.1101/2020.04.30.070839 — immunology — Posted on 2020-05-02
4914 Optimized photochemistry and enzymology enable efficient analysis of RNA structures and interactions in cells and virus infections
Zhang, M.; Li, K.; Velema, W. A.; Bai, J.; Yu, C.; van Damme, R.; Lee, W. H.; Corpuz, M. L.; Chen, J.-F.; Lu, Z.
10.1101/2020.04.30.071167 — genomics — Posted on 2020-05-02
4917 Analysis of circulating protein aggregates reveals pathological hallmarks of amyotrophic lateral sclerosis
Adiutori, R.; Puentes, F.; Bremang, M.; Lombardi, V.; Zubiri, I.; Leoni, E.; Aarum, J.; Sheer, D.; McArthur, S.; Pike, I.; Malaspina, A.
10.1101/2020.04.30.070979 — neuroscience — Posted on 2020-05-02
4923 Detecting Early Response to Immune Checkpoint Blockade by Multimodal Molecular Imaging
Saida, Y.; Brender, J. R.; Yamamoto, K.; Mitchell, J. B.; Krishna, M. C.; Kishimoto, S.
10.1101/2020.04.30.070508 — cancer biology — Posted on 2020-05-02
4924 Combined Effects of Standing and Passive Heating on Attenuating Sitting-Induced Vascular Dysfunction
Caldwell, A. R.; Jansen, L. T.; Rosa-Caldwell, M. E.; Howie, E. K.; Gallagher, K. M.; Turner, R. C.; Ganio, M. S.
10.1101/2020.04.30.060087 — physiology — Posted on 2020-05-02
4929 Macrophages can either inhibit or enhance endometriosis depending on their origin
Hogg, C.; Dhami, P.; Rosser, M.; Mack, M.; Soong, D.; Pollard, J. W.; Jenkins, S. J.; Horne, A. W.; Greaves, E.
10.1101/2020.04.30.070003 — immunology — Posted on 2020-05-02
4932 Pericyte-derived fibrotic scarring is conserved across diverse central nervous system lesions
Dias, D. O.; Kalkitsas, J.; Kelahmetoglu, Y.; Estrada, C. P.; Tatarishvili, J.; Ernst, A.; Huttner, H. B.; Kokaia, Z.; Lindvall, O.; Brundin, L.; Frisen, J.; Göritz, C.
10.1101/2020.04.30.068965 — neuroscience — Posted on 2020-05-02
4933 Upregulation of TRPM3 drives hyperexcitability in nociceptors innervating inflamed tissue.
Mulier, M.; Van Ranst, N.; Corthout, N.; Munck, S.; Vanden Berghe, P.; Vriens, J.; Voets, T.; Moilanen, L.
10.1101/2020.04.30.069849 — neuroscience — Posted on 2020-05-02
4935 Neonatal immune challenge induces female-specific changes in social behavior and somatostatin cell number, independent of microglial inflammatory signaling
Smith, C. J.; Kingsbury, M. A.; Dziabis, J. E.; Hanamsagar, R.; Malacon, K. E.; Tran, J. N.; Norris, H. A.; Gulino, M.; Bilbo, S. D.
10.1101/2020.04.30.068924 — neuroscience — Posted on 2020-05-02
4937 Optimised biomolecular extraction for metagenomic analysis of microbial biofilms from high-mountain streams
Busi, S. B.; Pramateftaki, P.; Brandani, J.; Fodelianakis, S.; Peter, H.; Halder, R.; Wilmes, P.; Battin, T.
10.1101/2020.04.30.069724 — molecular biology — Posted on 2020-05-02
4940 Trait-based responses to forestry and grazing modify long-term changes in biodiversity hot-spots of boreal forests
Happonen, K.; Muurinen, L.; Virtanen, R.; Kaakinen, E.; Grytnes, J.-A.; Kaarlejarvi, E.; Parisot, P.; Wolff, M.; Maliniemi, T.
10.1101/2020.04.30.069708 — ecology — Posted on 2020-05-02
4941 Chemical patterns of colony membership and mother-offspring similarity in Antarctic fur seals are reproducible over time
Tebbe, J.; Humble, E.; Stoffel, M. A.; Tewes, L. J.; Mueller, C.; Forcada, J.; Caspers, B.; Hoffman, J. I.
10.1101/2020.04.30.070193 — ecology — Posted on 2020-05-02
4942 Germination ecology of wild and domesticated Ensete ventricosum: Evidence for maintenance of sexual reproductive capacity in a vegetatively propagated perennial crop
Tamrat, S.; Borrell, J. S.; Shiferaw, E.; Kallow, S. S.; Davies, R. M.; Dickie, J. B.; Nuraga, G. W.; White, O.; Woldeyes, F.; Demissew, S.; Wilkin, P.
10.1101/2020.04.30.055582 — ecology — Posted on 2020-05-02
4943 Niche-based processes and neutrality influence patterns of indirect interactions in mutualistic networks
Simmons, B. I.; Beckerman, A. P.; Hansen, K.; Maruyama, P. K.; Vizentin-Bugoni, J. I.; Dalsgaard, B.
10.1101/2020.04.30.070391 — ecology — Posted on 2020-05-02
4945 Unannotated small RNA clusters in circulating extracellular vesicles detect early stage liver cancer
Felden, J. v.; Lezana, T. G.; Dogra, N.; Kozlova, E.; Ahsen, M. E.; Craig, A.; Gifford, S.; Wunsch, B.; Smith, J. T.; Kim, S.; Diaz, J. E.; Chen, X.; Labgaa, I.; Haber, P. K.; Olsen, R.; Han, D.; Restrepo, P.; D'Vola, D.; Allette, K.; Sebra, R.; Saberi, B.; Tabrizian, P.; Asgharpour, A.; Dietereich, D.; Llovet, J.; Cardo, C.; Tewari, A.; Schwartz, M.; Stolovitzky, G. A.; Losic, B.; Villanueva, A.
10.1101/2020.04.29.066183 — cancer biology — Posted on 2020-05-02
4946 Epigenetic therapy remodels the immune synaptic cytoskeleton to potentiate cancer susceptibility to γδ T cells
Weng, R. R.; Lu, H.-H.; Lin, C.-T.; Fan, C.-C.; Lin, R.-S.; Huang, T.-C.; Lin, S.-Y.; Huang, Y.-J.; Juan, Y.-H.; Wu, Y.-C.; Hung, Z.-C.; Liu, C.; Lin, X.-H.; Hsieh, W.-C.; Chiu, T.-Y.; Liao, J.-C.; Chiu, Y.-L.; Chen, S.-Y.; Yu, C.-J.; Tsai, H.-C.
10.1101/2020.04.30.069955 — cancer biology — Posted on 2020-05-02
4947 A machine learning approach to optimizing cell-free DNA sequencing panels: with an application to prostate cancer
Cario, C. L.; Chen, E.; Leong, L.; Emami, N. C.; Lopez, K.; Tenggara, I.; Simko, J. P.; Friedlander, T. W.; Li, P. S.; Paris, P. L.; Carroll, P. R.; Witte, J. S.
10.1101/2020.04.30.069658 — cancer biology — Posted on 2020-05-02
4948 Transcriptional profiling reveals a subset of human breast tumors that retain wt TP53 but display mutant p53-associated features
Oren, M.; Domany, E.; Benor, G.; Fuks, G.; Rueda, O.; Chin, S.-F.; Caldas, C.; mukherjee, s.; Arankar, S.; Aylon, Y.
10.1101/2020.04.30.070037 — cancer biology — Posted on 2020-05-02
4950 Heterosis of leaf and rhizosphere microbiomes in field-grown maize
Wagner, M. R.; Roberts, J. H.; Balint-Kurti, P. J.; Holland, J. B.
10.1101/2020.01.13.904979 — plant biology — Posted on 2020-05-02
4951 Neuronal Hyperexcitability is a DLK-dependent Trigger of HSV-1 Reactivation that can be Induced by IL-1
Cuddy, S. R.; Schinlever, A. R.; Dochnal, S.; Suzich, J. B.; Kundu, P.; Downs, T. K.; Farah, M.; Desai, B.; Boutell, C.; Cliffe, A. R.
10.1101/2020.04.16.044875 — microbiology — Posted on 2020-05-02
4952 Membrane-type 1 matrix metalloproteinase (MMP-14) modulates tissue homeostasis by a non-proteolytic mechanism
Attur, M. G.; Lu, C.; Zhang, X.; Han, T.; Alexandre, C.; Valacca, C.; Zheng, S.; Meikle, S.; Brukner Dabovic, B.; Tassone, E.; Yang, Q.; Kolupaeva, V.; Yakar, S.; Abramson, S. B.; Mignatti, P.
10.1101/631739 — cell biology — Posted on 2020-05-02
4954 Analyzing kinetic signaling data for G-protein-coupled receptors
Hoare, S. R. J.; Tewson, P. H.; Quinn, A. M.; Hughes, T. E.; Bridge, L. J.
10.1101/2020.01.20.913319 — pharmacology and toxicology — Posted on 2020-05-02
4956 Predicting Functional Associations using Flanking Genes (FlaGs)
Saha, C. K.; Sanches Pires, R.; Brolin, H.; Delannoy, M.; Atkinson, G. C.
10.1101/362095 — bioinformatics — Posted on 2020-05-02
4958 Freshwater monitoring by nanopore sequencing
Urban, L.; Holzer, A.; Baronas, J. J.; Hall, M.; Braeuninger-Weimer, P.; Scherm, M. J.; Kunz, D. J.; Perera, S. N.; Martin-Herranz, D. E.; Tipper, E. T.; Salter, S. J.; Stammnitz, M. R.
10.1101/2020.02.06.936302 — microbiology — Posted on 2020-05-02
4961 Shaky Scaffolding: Age Differences In Cerebellar Activation Revealed Through Activation Likelihood Estimation Meta-Analysis
Bernard, J.; Nguyen, A. D.; Hausman, H. K.; Maldonado, T.; Ballard, H. K.; Jackson, T. B.; Eakin, S. M.; Lokshina, Y.; Goen, J. R. M.
10.1101/716530 — neuroscience — Posted on 2020-05-02
4963 Multi-modal characterization and simulation of human epileptic circuitry
Buchin, A.; de Frates, R.; Nandi, A.; Mann, R.; Chong, P.; Ng, L.; Miller, J.; Hodge, R. D.; Kalmbach, B.; Bose, S.; Rutishauser, U.; McConoughey, S.; Lein, E.; Berg, J.; Sorensen, S.; Gwinn, R.; Koch, C.; Ting, J. T.; Anastassiou, C. A.
10.1101/2020.04.24.060178 — neuroscience — Posted on 2020-05-02
4965 High-resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica
Righetto, R. D.; Anton, L.; Adaixo, R.; Jakob, R. P.; Zivanov, J.; Mahi, M.-A.; Ringler, P.; Schwede, T.; Maier, T.; Stahlberg, H.
10.1101/2020.04.28.065599 — molecular biology — Posted on 2020-05-02
4967 Accurate, scalable cohort variant calls using DeepVariant and GLnexus
Yun, T.; Li, H.; Chang, P.-C.; Lin, M. F.; Carroll, A.; McLean, C. Y.
10.1101/2020.02.10.942086 — genomics — Posted on 2020-05-02
4970 Stable Biomarker Identification For Predicting Schizophrenia in the Human Connectome
Gutierrez-Gomez, L.; Vohryzek, J.; Chiem, B.; Baumann, P.; Conus, P.; Do Cuenod, K. Q.; Hagmann, P.; Delvenne, J.-C.
10.1101/711135 — neuroscience — Posted on 2020-05-02
4972 Functional properties of habenular neurons are determined by developmental stage and sequential neurogenesis
Fore, S.; Acuna-Hinrichsen, F.; Mutlu, K. A.; Bartoszek, E. M.; Serneels, B.; Faturos, N. G.; Chau, P.; Cosacak, M. I.; Diaz Verdugo, C.; Palumbo, F.; Ringers, C.; Jurisch-Yaksi, N.; Kizil, C.; Yaksi, E.
10.1101/722462 — neuroscience — Posted on 2020-05-02
4973 Unilateral vocal nerve resection alters neurogenesis in the avian song system in a region-specific manner
Aronowitz, J. V.; Perez, A.; O'Brien, C.; Aziz, S.; Rodriguez, E.; Wasner, K.; Ribeiro, S.; Green, D.; Faruk, F.; Pytte, C.
10.1101/2020.03.24.005330 — neuroscience — Posted on 2020-05-02
4974 Alterations in brain network organization in adults with obesity as compared to healthy-weight individuals and seniors
Ottino-Gonzalez, J.; Baggio, H. C.; Jurado, M. A.; Segura, B.; Caldu, X.; Prats-Soteras, X.; Tor, E.; Sender-Palacios, M. J.; Miro, N.; Sanchez-Garre, C.; Dadar, M.; Dagher, A.; Garcia Garcia, I.; Garolera, M.
10.1101/685081 — neuroscience — Posted on 2020-05-02
4975 Thetaburst TMS to the posterior superior temporal sulcus decreases resting-state fMRI connectivity across the face processing network
Handwerker, D. A.; Ianni, G.; Gutierrez, B.; Roopchansingh, V.; Gonzalez-Castillo, J. A.; Chen, G.; Bandettini, P. A.; Ungerleider, L. G.; Pitcher, D.
10.1101/794578 — neuroscience — Posted on 2020-05-02
4984 Molecular Basis for the Evolved Instability of a Human G-Protein Coupled Receptor
Chamness, L. M.; Zelt, N. B.; Kuntz, C. P.; Bender, B. J.; Penn, W. D.; Ziarek, J. J.; Meiler, J. P.; Schlebach, J. P.
10.1101/2019.12.20.884718 — biochemistry — Posted on 2020-05-02
4986 BioID analysis of the cyclin F interactome reveals that ALS-variant cyclin F alters the homeostasis of paraspeckle-associated proteins
Rayner, S. L.; Cheng, F.; Yang, S.; Grima, N.; Ke, Y. D.; Au, C. G.; Morsch, M.; De Luca, A.; Davidson, J. M.; Molloy, M. P.; Shi, B.; Ittner, L. M.; Blair, I.; Chung, R. S.; Lee, A.
10.1101/2020.04.30.071365 — neuroscience — Posted on 2020-05-01
4987 Release sites are positioned to activate NMDA receptors
Li, S.; Raychaudhuri, S.; Lee, S. A.; Wang, J.; Kusick, G. F.; Prater, C.; Syed, S.; Falahati, H.; Ramos, R.; Bartol, T. M.; Hosy, E.; Watanabe, S.
10.1101/2020.05.01.072157 — neuroscience — Posted on 2020-05-02
4991 Peroxisome counteracts oxidative stresses by suppressing catalase import via Pex14 phosphorylation
Fujiki, Y.; Okumoto, K.; Shermely, M. E.; Natsui, M.; Kosako, H.; Natsuyama, R.; Marutani, T.
10.1101/2020.05.01.072132 — cell biology — Posted on 2020-05-02
4993 Pazopanib induces dramatic but transient contraction of myeloid suppression compartment in favor of adaptive immunity
Rinchai, D.; Verzoni, E.; Huber, V.; Cova, A.; Squarcina, P.; Cecco, L. D.; Braud, F. d.; Ratta, R.; Dugo, M.; Lalli, L.; Vallacchi, V.; Rodolfo, M.; Roelands, J.; Castelli, C.; Chaussabel, D.; Procopio, G.; Bedognetti, D.; Rivoltini, L.
10.1101/2020.05.01.071613 — cancer biology — Posted on 2020-05-01
4995 Neurodevelopmental deficits and cell-type-specific transcriptomic perturbations in a mouse model of HNRNPU haploinsufficiency
Dugger, S. A.; Dhindsa, R. S.; De Almeida Sampaio, G.; Rafikian, E.; Petri, S.; Teoh, J.; Ye, J.; Colombo, S.; Yang, M.; Boland, M.; Frankel, W.; Goldstein, D.
10.1101/2020.05.01.072512 — neuroscience — Posted on 2020-05-01
4997 Evidences of histologic Thrombotic Microangiopathy and the impact in renal outcomes of patients with IgA nephropathy
Neves, P. D. M. d. M.; Souza, R. A.; Torres, F. M.; Reis, F. A.; Pinheiro, R. B.; Dias, C. B.; Yu, L.; Woronik, V.; Furukawa, L. S.; Cavalcante, L. B.; Malheiros, D. M.; Jorge, L. B.
10.1101/2020.05.01.072074 — immunology — Posted on 2020-05-01
5000 Evidence for unique small RNA modifications in Alzheimers disease
Zhang, X.; Trebak, F.; Souza, L. A. C.; Shi, J.; Zhou, T.; Kehoe, P. G.; Chen, Q.; Feng Earley, Y.
10.1101/2020.04.30.071100 — cell biology — Posted on 2020-05-01
5001 On spatial molecular arrangements of SARS-CoV2 genomes of Indian patients
Hassan, S. S.; Moitrab, A.; Rout, R. K.; Choudhury, P. P.; Pramanik, P.; Jana, S. S.
10.1101/2020.05.01.071985 — bioinformatics — Posted on 2020-05-01
5002 The complete genome sequence of the Staphylococcus bacteriophage Metroid
Crane, A.; Abaidoo, J.; Beltran, G.; Fry, D.; Furey, C.; Green, N.; Johal, R.; La Rosa, B.; Lopez Jimenez, C.; Luong, L.; Maag, G.; Porche, J.; Reyes, L.; Robinson, A.; Sabbara, S.; Soto Herrera, L.; Urquidez Negrete, A.; Wilson, P.; Geiler-Samerotte, K.; Pfeifer, S. P.
10.1101/2020.05.01.072256 — genomics — Posted on 2020-05-01
5003 Developmental co-emergence of cardiac and gut tissues modeled by human iPSC-derived organoids
Silva, A. C.; Matthys, O. B.; Joy, D. A.; Kauss, M. A.; Natarajan, V.; Lai, M. H.; Turaga, D.; Alexanian, M.; Bruneau, B. G.; McDevitt, T. C.
10.1101/2020.04.30.071472 — developmental biology — Posted on 2020-05-01
5005 New insights into how MutS separates its function in the regulation of the Pol IV access to replication sites from that in the conserved MMR pathway
Ibanez, M. I.; Margara, L. M.; Castell, S. D.; Fernandez, M. M.; Malchiodi, E. L.; Montich, G. G.; Miguel, V.; Argarana, C. E.; Monti, M. R.
10.1101/2020.05.01.070730 — biochemistry — Posted on 2020-05-01
5007 Barbadin selectively modulates FPR2-mediated neutrophil functions independent of receptor endocytosis
Sundqvist, M.; Holdfeldt, A.; Wright, S.; Moller, T.; Siaw, E.; Jennbacken, K.; Franzyk, H.; Bouvier, M.; Dahlgren, C.; forsman, h.
10.1101/2020.04.30.070011 — pharmacology and toxicology — Posted on 2020-05-01
5009 Impaired hand dexterity function in a non-human primate model with chronic Parkinson's disease
Seo, J.; Won, J.; Kim, K.; Park, J.; Yeo, H.-G.; Kim, Y. G.; Baek, S. H.; Lee, H.; Jeon, C.-Y.; Choi, W. S.; Lee, S.; Kim, K. J.; Park, S.-H.; Son, Y.; Jeong, K. J.; Lim, K. S.; Kang, P.; Lee, H.-Y.; Son, H.-C.; Huh, J.-W.; Kim, Y.-H.; Jin, Y. B.; Lee, D.-S.; Lee, S.-R.; Choi, J.-W.; Lee, Y.
10.1101/2020.05.01.072058 — neuroscience — Posted on 2020-05-01
5014 Actinobacillus utilizes a binding-protein dependent ABC transporter to acquire Vitamin B6
Pan, C.; Zimmer, A.; Shah, M.; Huynh, M.; Lai, C. C.; Sit, B.; Hooda, Y.; Curran, D.; Moraes, T. F.
10.1101/2020.05.01.072959 — biochemistry — Posted on 2020-05-01
5017 New genotypic adaptability and stability analyses using Legendre polynomials and genotype-ideotype distances
de Souza, M. H.; Pereira Junior, J. D.; Steckling, S. D. M.; Mencalha, J.; Dias, F. d. S.; Rocha, J. R. d. A. S. d. C.; Carneiro, P. C. S.; Carneiro, J. E. d. S.
10.1101/2020.05.01.072090 — genetics — Posted on 2020-05-01
5018 SARS-CoV-2 spike protein predicted to form stable complexes with host receptor protein orthologues from mammals, but not fish, birds or reptiles
Lam, S. D.; Bordin, N.; Waman, V. P.; Scholes, H. M.; Ashford, P.; Sen, N.; van Dorp, L.; Rauer, C.; Dawson, N. L.; Pang, C. S.; Abbasian, M.; Sillitoe, I.; Edwards, S. J.; Fraternali, F.; Lees, J. G.; Santini, J. M.; Orengo, C. A.
10.1101/2020.05.01.072371 — bioinformatics — Posted on 2020-05-01
5019 GCN sensitive protein translation in yeast
Barr, W. A.; Sheth, R. B.; Kwon, J.; Cho, J.; Glickman, J. W.; Hart, F.; Chatterji, O.; Scopino, K.; Voelkel-Meiman, K.; Krizanc, D.; Thayer, K. M.; Weir, M. P.
10.1101/2020.05.01.072066 — molecular biology — Posted on 2020-05-01
5020 The STRIPAK signaling complex regulates phosphorylation of GUL1, an RNA-binding protein that shuttles on endosomes
Stein, V.; Blank-Landeshammer, B.; Müntjes, K.; Märker, R.; Teichert, I.; Feldbrügge, M.; Sickmann, A.; Kück, U.
10.1101/2020.05.01.072009 — genetics — Posted on 2020-05-01
5021 All-Atom Simulation of the HET-s Prion Replication
Terruzzi, L.; Spagnolli, G.; Boldrini, A.; Requena, J. R.; Biasini, E.; faccioli, p.
10.1101/2020.05.01.072017 — biophysics — Posted on 2020-05-01
5023 Lack of Reinfection in Rhesus Macaques Infected with SARS-CoV-2
Bao, L.; Deng, W.; Gao, H.; Xiao, C.; Liu, J.; Xue, J.; Lv, Q.; Liu, J.; Yu, P.; Xu, Y.; Qi, F.; Qu, Y.; Li, F.; Xiang, Z.; Yu, H.; Gong, S.; Liu, M.; Wang, G.; Wang, S.; Song, Z.; Liu, Y.; Zhao, W.; Han, Y.; Zhao, L.; Liu, X.; Wei, Q.; Qin, C.
10.1101/2020.03.13.990226 — microbiology — Posted on 2020-05-01
5027 SARS-CoV2 quantification using RT-dPCR: a faster and safer alternative to assist viral genomic copies assessment using RT-qPCR
Almeida, P. R.; Demoliner, M.; Antunes Eisen, A. K.; Heldt, F. H.; Hansen, A. W.; Schallenberger, K.; Fleck, J. D.; Spilki, F. R.
10.1101/2020.05.01.072728 — molecular biology — Posted on 2020-05-01
5028 Shotgun Transcriptome and Isothermal Profiling of SARS-CoV-2 Infection Reveals Unique Host Responses, Viral Diversification, and Drug Interactions
Butler, D. J.; Mozsary, C.; Meydan, C.; Danko, D. C.; Foox, J.; Rosiene, J.; Shaiber, A.; Afshinnekoo, E.; MacKay, M.; Sedlazeck, F. J.; Ivanov, N. A.; Sierra, M. A.; Pohle, D.; Zietz, M.; Gisladottir, U.; Ramlall, V.; Westover, C. D.; Ryon, K.; Young, B.; Bhattacharya, C.; Ruggiero, P.; Langhorst, B. W.; Tanner, N. A.; Gawrys, J.; Meleshko, D.; Xu, D.; Steel, P. A. D.; Shemesh, A. J.; Xiang, J.; Thierry-Mieg, J.; Thierry-Mieg, D.; Schwartz, R. E.; Iftner, A.; Bezdan, D.; Sipley, J.; Cong, L.; Craney, A.; Velu, P.; Melnick, A.; Hajirasouliha, I.; Horner, S. M.; Iftner, T.; Salvatore, M.; Loda,
10.1101/2020.04.20.048066 — molecular biology — Posted on 2020-05-01
5029 Distinct Inductions of and Responses to Type I and Type III Interferons PromoteInfections in Two SARS-CoV-2 Isolates
Hsin, F.; Chao, T.-L.; Chan, Y.-R.; Kao, H.-C.; Liu, W.-D.; Wang, J.-T.; Pang, Y.-H.; Lin, C.-H.; Tsai, Y.-M.; Lin, J.-Y.; Chang, S.-Y.; Liu, H. M.
10.1101/2020.04.30.071357 — microbiology — Posted on 2020-05-01
5030 SARS-CoV-2 genomes recovered by long amplicon tiling multiplex approach using nanopore sequencing and applicable to other sequencing platforms
Resende, P. C.; Motta, F. C.; Roy, S.; Appolinario, L.; Fabri, A.; Xavier, J.; Harris, K.; Matos, A. R.; Caetano, B. C.; Garcia, C. C.; Miranda, M. D.; Ogrzewalska, M.; Abreu, A.; Williams, R.; Breuer, J.; Siqueira, M. M.
10.1101/2020.04.30.069039 — molecular biology — Posted on 2020-05-01
5031 Potent antiviral effect of protoporphyrin IX and verteporfin on SARS-CoV-2 infection
Gu, C.; Wu, Y.; Guo, H.; Zhu, Y.; Xu, W.; Wang, Y.; Sun, Z.; Cai, X.; Li, Y.; Liu, J.; Yuan, Z.; Zhang, R.; Deng, Q.; Qu, D.; Xie, Y.
10.1101/2020.04.30.071290 — microbiology — Posted on 2020-05-01
5032 Comparative transcriptome analysis reveals the intensive early-stage responses of host cells to SARS-CoV-2 infection
Sun, J.; Ye, F.; Wu, A.; Yang, R.; Pan, M.; Sheng, J.; Zhu, W.; Mao, L.; Wang, M.; Huang, B.; Tan, W.; Jiang, T.
10.1101/2020.04.30.071274 — microbiology — Posted on 2020-05-01
5033 Molecular Architecture of Early Dissemination and Evolution of the SARS-CoV-2 Virus in Metropolitan Houston, Texas
Long, S. W.; Christensen, P. A.; Bernard, D. W.; Davis, J. R.; Shukla, M.; Nguyen, M.; Saavedra, M. O.; Cantu, C. C.; Yerramilli, P.; Pruitt, L.; Subedi, S.; Hendrickson, H.; Eskandari, G.; Kumaraswami, M.; McLellan, J. S.; Musser, J. M.
10.1101/2020.05.01.072652 — genetics — Posted on 2020-05-01
5034 Dysregulation in mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells
Appelberg, S.; Gupta, S.; Ambikan, A. T.; Mikaeloff, F.; Vegvari, A.; Svensson Akusjarvi, S.; Benfeitas, R.; Sperk, M.; Stahlberg, M.; Krishnan, S.; Singh, K.; Penninger, J. M.; Mirazimi, A.; Neogi, U.
10.1101/2020.04.30.070383 — microbiology — Posted on 2020-05-01
5036 Broad-spectrum antiviral activity of naproxen: from Influenza A to SARS-CoV-2 Coronavirus
Terrier, O.; Dilly, S.; Pizzorno, M.-A.; Henri, J.; Berenbaum, F.; Lina, B.; Feve, B.; Adnet, F.; Sabbah, M.; Rosa-Calavatra, M.; Marechal, V.; Slama-Schwok, A.
10.1101/2020.04.30.069922 — microbiology — Posted on 2020-05-01
5037 Population genomic analyses of schistosome parasites highlight critical challenges facing end-game elimination efforts
Shortt, J. A.; Timm, L. E.; Hales, N. R.; Nikolakis, Z. L.; Schield, D. R.; Perry, B. W.; Liu, Y.; Zhong, B.; Castoe, T. A.; Carlton, E. J.; Pollock, D. D.
10.1101/2020.04.30.070656 — evolutionary biology — Posted on 2020-05-01
5038 The search for sexually antagonistic genes: Practical insights from studies of local adaptation and statistical genomics
Ruzicka, F.; Dutoit, L.; Czuppon, P.; Jordan, C. Y.; Li, X.-Y.; Olito, C.; Papoli Yazdi, H.; Runemark, A.; Svensson, E. I.; Connallon, T.
10.1101/2020.04.30.071191 — evolutionary biology — Posted on 2020-05-01
5042 Evidences of histologic Thrombotic Microangiopathy and the impact in renal outcomes of patients with IgA nephropathy
Neves, P. D. M. d. M.; Souza, R. A.; Torres, F. M.; Reis, F. A.; Pinheiro, R. B.; Dias, C. B.; Yu, L.; Woronik, V.; Furukawa, L. S.; Cavalcante, L. B.; Malheiros, D. M.; Jorge, L. B.
10.1101/2020.05.01.072074 — immunology — Posted on 2020-05-01
5043 The prolyl hydroxylase PHD3 maintains β-cell glucose metabolism during fatty acid excess
Nasteska, D.; Cuozzo, F.; Thakker, A.; Bany Bakar, R.; Westbrook, R.; Akerman, I.; Cantley, J.; Tennant, D. A.; Hodson, D. J.
10.1101/2020.04.30.068106 — physiology — Posted on 2020-05-01
5047 Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms
von Loeffelholz, O.; Purkiss, A.; Cao, L.; Kjaer, S.; Kogata, N.; Romet-Lemonne, G.; Way, M.; Moores, C. A.
10.1101/2020.05.01.071704 — biophysics — Posted on 2020-05-01
5050 Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis
Xu, C.; Fisher, D.; Rankovic, S.; Li, W.; Dick, R.; Runge, B.; Zadorozhnyi, R.; Ahn, J.; Aiken, C.; Polenova, T.; Engelman, A.; Ambrose, Z.; Rousso, I.; Perilla, J. R.
10.1101/2020.04.30.071217 — biophysics — Posted on 2020-05-01
5051 A Workflow for Protein Structure Determination from Thin Crystal Lamella by Micro-Electron Diffraction
Beale, E. V.; Waterman, D. G.; van Rooyen, J.; Gilchrist, J. B.; Parkhurst, J. M.; de Haas, F.; Buijsse, B.; Evans, G.; zhang, p.
10.1101/2020.04.30.061895 — biophysics — Posted on 2020-05-01
5052 GRP78 and Integrins Play Different Roles in Host Cell Invasion During Mucormycosis
Alqarihi, A.; Gebremariam, T.; Gu, Y.; Swidergall, M.; Alkhazraji, S.; Soliman, s.; Bruno, V.; Edwards, J.; Filler, S.; Uppuluri, P.; Ibrahim, A. S.
10.1101/2020.04.29.069666 — microbiology — Posted on 2020-05-01
5054 Histone deacetylase inhibitors butyrate and bufexamac inhibit de novo HIV-1 infection in CD4 T-cells
Schölz, C.; Chen, L.; Zutz, A.; Keppler, O. T.; Philippou-Massier, J.; Blum, H.; Liebner, T.; Choudhary, C.
10.1101/2020.04.29.067884 — microbiology — Posted on 2020-05-01
5055 Atypical meiosis can be adaptive in outcrossed S. pombe due to wtf meiotic drivers
Bravo Nunez, M. A.; Sabbarini, I. M.; Eide, L. E.; Unckless, R. L.; Zanders, S. E.
10.1101/2020.04.28.066035 — evolutionary biology — Posted on 2020-05-01
5056 Notch and TLR signaling coordinate monocyte cell fate and inflammation
Gamrekelashvili, J.; Kapanadze, T.; Sablotny, S.; Ratiu, C.; Dastagir, K.; Lochner, M.; Karbacher, S.; Wenzel, P.; Sitnow, A.; Fleig, S.; Sparwasser, T.; Kalinke, U.; Haller, H.; Holzmann, B.; Limbourg, F.
10.1101/2020.04.28.066217 — immunology — Posted on 2020-05-01
5057 Post-mitotic expansion of cell nuclei requires ACTN4-mediated nuclear actin filament bundling
Grosse, R.; Krippner, S.; Winkelmeier, J.; Schwan, C.; Knerr, J.; Virant, D.; Endesfelder, U.
10.1101/2020.04.29.067488 — cell biology — Posted on 2020-05-01
5058 Specificity of Gβ and γ subunits to SNARE complex both at rest and after α2aadrenergic receptor stimulation
Yim, Y. Y.; McDonald, W. H.; Betke, K. M.; Kaya, A.; Hyde, K.; Gilsbach, R.; Hein, L.; Hamm, H. E.
10.1101/2020.04.29.065136 — biochemistry — Posted on 2020-05-01
5059 Structural and functional analysis of pyocin S8 from Pseudomonas aeruginosa : requirement of a glutamate in the H-N-H motif for the DNase activity.
Turano, H. G.; Fomes, F.; Domingos, R. M.; Degenhardt, M. F. S.; Oliveira, C. L. P.; Garratt, R. C.; Lincopan, N.; Netto, L. E. S.
10.1101/2020.04.29.068437 — molecular biology — Posted on 2020-05-01
5060 The RNA Polymerase II core subunit RPB-9 directs transcriptional elongation at piRNA loci in Caenorhabditis elegans
Berkyurek, A. C.; Lampersberger, L.; Furlan, G.; Beltran, T.; Weick, E.-M.; Nischwitz, E.; Navarro, I. C.; Braukmann, F.; Akay, A.; Price, J.; Butter, F.; Sarkies, P.; Miska, E. A.
10.1101/2020.05.01.070433 — genetics — Posted on 2020-05-01
5063 Dendritic cells require TMEM176A/B ion channels for optimal MHC II antigen presentation to naive CD4+ T cells
Lancien, M.; Bienvenu, G.; Gueno, L.; Salle, S.; Merieau, E.; Remy, S.; Even, A.; Moreau, A.; Molle, A.; Fourgeux, C.; Coulon, F.; Beriou, G.; Bouchet-Delbos, L.; Chiffoleau, E.; Kirstetter, P.; Chan, S.; Kerfoot, S.; Abdu Rahiman, S.; De Simone, V.; Matteoli, G.; Boncompain, G.; Perez, F.; Josien, R.; Poschmann, J.; Cuturi, M. C.; Louvet, C.
10.1101/851527 — immunology — Posted on 2020-05-01
5064 B1 and B2 B cells are characterized by distinct CpG modification states at DNMT3A-maintained enhancers
Mahajan, V. S.; Mattoo, H.; Sun, N.; Viswanadham, V. V.; Yuen, G. J.; Allard-Chamard, H.; Ahmad, M.; Murphy, S. J. H.; Annaiah, C.; Tuncay, Y.; Pillai, S.
10.1101/2020.04.30.071209 — immunology — Posted on 2020-05-01
5066 A transient role of primary cilia in controlling direct versus indirect neurogenesis in the developing cerebral cortex
Hasenpusch-Theil, K.; Laclef, C.; Colligan, M.; Fitzgerald, E.; Howe, K.; Carroll, E.; Abrams, S.; Reiter, J. F.; Schneider-Maunoury, S.; Theil, T.
10.1101/2020.04.28.065615 — developmental biology — Posted on 2020-05-01
5067 Brassinosteroids Influence Arabidopsis Hypocotyl Graviresponses Through Changes In Mannans And Cellulose
Somssich, M.; Vandenbussche, F.; Ivakov, A.; Funke, N.; Ruprecht, C.; Vissenberg, K.; Van Der Straeten, D.; Persson, S.; Suslov, D.
10.1101/557777 — plant biology — Posted on 2020-05-01
5068 Enhanced differentiation of functional human T cells in NSGW41 mice with tissue-specific expression of human interleukin-7.
Coppin, E.; Sundarasetty, B. S.; Rahmig, S.; Blume, J.; Verheyden, N. A.; Bahlmann, F.; Ravens, S.; Schubert, U.; Schmid, J.; Ludwig, S.; von Kaisenberg, C.; Platz, A.; Naumann, R.; Ludwig, B.; Prinz, I.; Waskow, C.; Krueger, A.
10.1101/2020.04.24.060319 — immunology — Posted on 2020-05-01
5072 SARM1 depletion rescues NMNAT1 dependent photoreceptor cell death and retinal degeneration.
Sasaki, Y.; Kakita, H.; Kubota, S.; Sene, A.; Lee, T. J.; Ban, N.; Dong, Z.; Lin, J. B.; Boye, S. L.; DiAntonio, A.; Boye, S. E.; Apte, R. S.; Milbrandt, J.
10.1101/2020.04.30.069385 — neuroscience — Posted on 2020-05-01
5075 Periodic propagating waves coordinate RhoGTPase network dynamics at the leading and trailing edges during cell migration
Bolado-Carrancio, A.; Rukhlenko, O. S.; Nikonova, E.; Tsyganov, M. A.; Wheeler, A.; Munoz, A. G.; Kolch, W.; von Kriegsheim, A.; Kholodenko, B. N.
10.1101/2020.03.09.984054 — systems biology — Posted on 2020-05-01
5077 Hypothalamic circuitry underlying stress-induced insomnia and peripheral immunosuppression
Li, S.-B.; Borniger, J. C.; Yamaguchi, H.; Hédou, J.; Gaudillière, B.; de Lecea, L.
10.1101/2020.04.29.069393 — neuroscience — Posted on 2020-05-01
5080 Cell-type specific gene expression profiling in heterogeneous in vitro cultures using epitope-tagged RPL22
Gregory, J. A.; Hoelzli, E.; Abdelaal, R.; Braine, C.; Cuevas, M.; Halpern, M.; Kang, K.; Barretto, N.; Akbalik, G.; Schrode, N.; Cheng, E.; Bowles, K. R.; Lotz, S.; Goderie, S.; Karch, C.; Goate, A. M.; temple, S.; Brennand, K.; Phatnani, H.
10.1101/2020.04.30.064709 — molecular biology — Posted on 2020-05-01
5082 High-resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica
Righetto, R. D.; Anton, L.; Adaixo, R.; Jakob, R. P.; Zivanov, J.; Mahi, M.-A.; Ringler, P.; Schwede, T.; Maier, T.; Stahlberg, H.
10.1101/2020.04.28.065599 — molecular biology — Posted on 2020-05-01
5083 Dendritic cells require TMEM176A/B ion channels for optimal MHC II antigen presentation to naive CD4+ T cells
Lancien, M.; Bienvenu, G.; Gueno, L.; Salle, S.; Merieau, E.; Remy, S.; Even, A.; Moreau, A.; Molle, A.; Fourgeux, C.; Coulon, F.; Beriou, G.; Bouchet-Delbos, L.; Chiffoleau, E.; Kirstetter, P.; Chan, S.; Kerfoot, S.; Abdu Rahiman, S.; De Simone, V.; Matteoli, G.; Boncompain, G.; Perez, F.; Josien, R.; Poschmann, J.; Cuturi, M. C.; Louvet, C.
10.1101/851527 — immunology — Posted on 2020-05-01
5084 Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction
Safi, F.; Dhapola, P.; Warsi, S.; Erlandsson, E.; Sitnicka, E.; Bryder, D.; Boiers, C.; Thakur, R. K.; Karlsson, G.
10.1101/2020.04.29.069062 — cell biology — Posted on 2020-05-01
5085 Tumor -Associated MUC1 Regulates TGF-β Signaling and Function in Pancreatic Ductal Adenocarcinoma
Grover, P.; Nath, S.; Bose, M.; Sanders, A. J.; Brouwer, C.; Fnu, N.; Zhou, R.; Yazdanifar, M.; Ahmed, M.; Wu, S.-t.; Truman, A. W.; Mukherjee, P.
10.1101/2020.04.29.068577 — cancer biology — Posted on 2020-05-01
5092 Enterohepatic transcription factor CREB3L3 protects atherosclerosis via SREBP competitive inhibition
Shimano, H.; Nakagawa, Y.; Yunong Wang, Y.; Han, S.-i.; Okuda, K.; Oishi, A.; Yagishita, Y.; Kumagai, K.; Ohno, H.; Osaki, Y.; Mizunoe, Y.; Murayama, Y.; Iwasaki, H.; Konishi, M.; Itoh, N.; Matsuzaka, T.; Sone, H.; Yamada, N.; Araki, M.
10.1101/2020.04.29.069260 — physiology — Posted on 2020-05-01
5096 Leveraging biological complexity to predict patch occupancy in a recent host range expansion
Forister, M.; Philbin, C.; Marion, Z.; Buerkle, C. A.; Dodson, C.; Fordyce, J.; Forister, G.; Lebeis, S.; Lucas, L.; Nice, C.; Gompert, Z.
10.1101/2020.04.29.069559 — ecology — Posted on 2020-05-01
5097 Epigenetic feedback and stochastic partitioning during cell division can drive resistance to EMT
Jia, W.; Tripathi, S.; Chakraborty, P.; Chedere, A.; Rangarajan, A.; Levine, H.; Jolly, M. K.
10.1101/2020.04.29.068239 — cancer biology — Posted on 2020-05-01
5100 Conformational Selection in Ligand Recognition by the First Tudor Domain of PHF20L1
Lv, M.; Gao, J.; Li, M.; Ma, R.; Li, F.; Liu, Y.; Liu, M.; Zhang, J.; Yao, X.; Wu, J.; Shi, Y.; Tang, Y.; Pan, Y.; Zhang, Z.; Ruan, K.
10.1101/2020.04.29.069500 — biochemistry — Posted on 2020-05-01
5101 Experimental Stroke Induces Chronic Gut Dysbiosis and Neuroinflammation in Male Mice
Brichacek, A. L.; Nwafor, D. C.; Benkovic, S. A.; Chakraborty, S.; Kenney, S. M.; Mace, M.; Jun, S.; Gambill, C. A.; Wang, W.; Hu, H.; Ren, X.; Povroznik, J. M.; Engler-Chiurazzi, E. B.; Primerano, D.; Denvir, J.; Percifield, R.; Infante, A.; Franko, J.; Schafer, R.; Gemoets, D. E.; Brown, C. M.
10.1101/2020.04.29.069575 — neuroscience — Posted on 2020-05-01
5105 Spatial confinement and temporal dynamics of selectin ligands enable stable hematopoietic stem cell rolling
Al Alwan, B.; AbuZineh, K.; Nozue, S.; Rakhmatulina, A.; Aldehaiman, M.; Al-Amoodi, A. S.; Serag, M. F.; Aleisa, F. A.; Merzaban, J. S.; Habuchi, S.
10.1101/2020.04.29.069617 — biophysics — Posted on 2020-05-01
5108 Fractional re-distribution among cell motility states during ageing
Phillip, J. M.; Zamponi, N.; Phillip, M. P.; Daya, J.; McGovern, S.; Williams, W.; Tschudi, K.; Jayatilaka, H.; Wu, P.-H.; Walston, J.; Wirtz, D.
10.1101/2020.04.29.069286 — bioengineering — Posted on 2020-05-01
5114 Neuronal Hyperexcitability is a DLK-dependent Trigger of HSV-1 Reactivation that can be Induced by IL-1
Cuddy, S. R.; Schinlever, A. R.; Dochnal, S.; Suzich, J. B.; Kundu, P.; Downs, T. K.; Farah, M.; Desai, B.; Boutell, C.; Cliffe, A. R.
10.1101/2020.04.16.044875 — microbiology — Posted on 2020-05-01
5116 Site-specific glycosylation mapping of Fc gamma receptor IIIb from neutrophils of health donors
Wojcik, I.; Senard, T.; de Graaf, E. L.; Janssen, G. M.; de Ru, A. H.; Mohammed, Y.; van Veelen, P. A.; Vidarsson, G.; Wuhrer, M.; Falck, D.
10.1101/2020.04.29.068742 — immunology — Posted on 2020-05-01
5122 An incoherent feedforward loop interprets NFκB/RelA dynamics to determine TNF-induced necroptosis decisions
Oliver Metzig, M.; Tang, Y.; Mitchell, S.; Taylor, B.; Foreman, R.; Wollman, R.; Hoffmann, A.
10.1101/2020.04.30.070888 — systems biology — Posted on 2020-05-01
5125 A Disinhibitory Circuit for Contextual Modulation in Primary Visual Cortex
Keller, A. J.; Dipoppa, M.; Roth, M. M.; Caudill, M.; Ingrosso, A.; Miller, K. D.; Scanziani, M.
10.1101/2020.01.31.929166 — neuroscience — Posted on 2020-05-01
5126 Suicidal thoughts, behaviors, and event-related potentials: A meta-analysis
Gallyer, A. J.; Dougherty, S. P.; Burani, K.; Albanese, B. J.; Joiner, T. E.; Hajcak, G.
10.1101/2020.04.29.069005 — neuroscience — Posted on 2020-05-01
5127 Sniff-synchronized, gradient-guided olfactory search by freely-moving mice
Findley, T. M.; Wyrick, D. G.; Cramer, J. L.; Brown, M. A.; Holcomb, B.; Attey, R.; Yeh, D.; Monasevitch, E.; Nouboussi, N.; Cullen, I.; Songco, J.; King, J. F.; Ahmadian, Y.; Smear, M. C.
10.1101/2020.04.29.069252 — neuroscience — Posted on 2020-05-01
5128 Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses
Zonneveld, M. I.; Herwijnen, M. J. C.; Fernandez-Gutierrez, M. M.; Giovanazzi, A.; de Groot, A. M.; Kleinjan, M.; van Capel, T. M. M.; Sijts, A. J. A. M.; Taams, L. S.; Garssen, J.; de Jong, E. C.; Kleerebezem, M.; Nolte-'t Hoen, E. N. M.; Redegeld, F. A.; Wauben, M. H. M.
10.1101/2020.04.29.068841 — immunology — Posted on 2020-05-01
5130 1q21.3 amplification modulates therapy sensitivity in Triple-Negative Breast Cancer
Chirravuri Venkata, R.; Ghersi, D.; Ganti, A. K.; Lakshmanan, I.; Chaudhary, S.; Batra, S. K.; Nasser, M. W.
10.1101/2020.04.29.066993 — cancer biology — Posted on 2020-05-01
5134 Multiplexed whole animal imaging with reversibly switchable optoacoustic proteins
Mishra, K.; Stankevych, M.; Fuenzalida-Werner, J. P.; Grassmann, S.; Gujrati, V.; Klemm, U.; Buchholz, V. R.; Ntziachristos, V.; Stiel, A. C.
10.1101/2020.02.01.930222 — biochemistry — Posted on 2020-05-01
5135 Establishment of a stable transgenic g6pdM1315-1443 zebrafish line with glucose-6-phosphate dehydrogenase deficiency
Shang, L.-J.; Song, J.; Xia, H.-X.; Tuo, Y.-Y.; Ren, P.-P.; Wu, X.-J.; Zhou, Y.-H.; Jin, J.; Ye, C.; He, Z.-X.; Shu, L.
10.1101/2020.04.30.068981 — zoology — Posted on 2020-05-01
5139 Characterization of Vibrio cholerae isolates from freshwater sources in northwest Ohio
Daboul, J.; Weghorst, L.; DeAngelis, C.; Plecha, S.; Saul-McBeth, J.; Matson, J. S.
10.1101/2020.04.30.070565 — microbiology — Posted on 2020-05-01
5141 Effects of agricultural systems on the anuran diversity in the Colombian amazon
Diaz Ricaurte, J. C.; Arriga Villegas, N. C.; Lopez Coronado, J. D.; Macias Garzon, G. X.; Ferreto Fiorillo, B.
10.1101/2020.04.29.068940 — ecology — Posted on 2020-05-01
5142 Comparative analysis of genome-wide DNA methylation identifies patterns that associate with conserved transcriptional programs in osteosarcoma
Mills, L. J.; Scott, M.; Shah, P.; Cunanan, A. R.; Deshpande, A.; Auch, B.; Curtin, B.; Beckman, K. B.; Spector, L. G.; Sarver, A. L.; Subramanian, S.; Richmond, T.; Modiano, J. F.
10.1101/2020.04.29.068155 — cancer biology — Posted on 2020-05-01
5145 The heart microbiome of insectivorous bats from Central and South Eastern Europe
Corduneanu, A.; Mihalca, A. D.; Sandor, A.; Hornok, S.; Malmberg, M.; PinViso, N.; Bongcam-Rudloff, E.
10.1101/2020.04.30.069815 — microbiology — Posted on 2020-05-01
5151 A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues
Nims, R.; Pferdehirt, L.; Ho, N.; Savadipour, A.; Lorentz, J.; Sohi, S.; Kassab, J.; Ross, A.; O'Conor, C.; Liedtke, W.; Zhang, B.; McNulty, A.; Guilak, F.
10.1101/2020.04.29.069294 — synthetic biology — Posted on 2020-05-01
5152 A way to break bones? The weight of intuitiveness
Vettese, D.; Stavrova, T.; Borel, A.; Marin, J.; Moncel, M.-H.; Arzarello, M.; Daujeard, C.
10.1101/2020.03.31.011320 — paleontology — Posted on 2020-05-01
5153 Cognitive Deficits and Altered Functional Brain Network Organization in Pediatric Brain Tumor Patients
Anandarajah, H.; Seitzman, B. A.; McMichael, A.; Dworetsky, A.; Coalson, R. S.; Jiang, C.; Gu, H.; Barbour, D. L.; Schlaggar, B. L.; Limbrick, D. D.; Rubin, J. B.; Shimony, J. S.; Perkins, S. M.
10.1101/2020.04.22.055459 — neuroscience — Posted on 2020-05-01
5154 Isolation and characterization of multi-protein complexes enriched in the K-Cl co-transporter 2 from brain plasma membranes
Smalley, J. L.; Kontou, G.; Choi, C.; Ren, Q.; Albrecht, D.; Abiraman, K.; Rodriguez Santos, M. A.; Bope, C. E.; Deeb, T. Z.; Davies, P. A.; Brandon, N. J.; Moss, S. J.
10.1101/2020.04.30.071076 — neuroscience — Posted on 2020-05-01
5156 Profiling the effect of nafcillin on HA-MRSA D592 using bacteriological and physiological media
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