bioRxiv directory

Hiroshi Tamura;Masa-aki Sato;Mitsuo Kawato;Keisuke Toyama

10.1101/220301 — neuroscience — Posted on 2017-11-16

3 Hyperacuity Bayesian methods to enhance temporal resolution of two-photon recording of the complex spikes in the cerebellar Purkinje cells

Huu Hoang;Masa-aki Sato;Mitsuo Kawato;Keisuke Toyama;Joseph R Madsen;Orrin Devinsky;Werner Doyle;Daniel Fabo;Sydney S Cash;Eric Halgren

10.1101/220350 — neuroscience — Posted on 2017-11-16

4 Heterogeneous origins of human sleep spindles in different cortical layers

Donald J Hagler;Istvan Ulbert;Lucia Wittner;Lorand Eross;Joseph R Madsen;Orrin Devinsky;Werner Doyle;Daniel Fabo;Sydney S Cash;Eric Halgren

10.1101/221234 — neuroscience — Posted on 2017-11-17

5 Discovery of a new song mode in Drosophila reveals hidden structure in the sensory and neural drivers of behavior

Jan Clemens;Pip Coen;Frederic Roemschied;Talmo Pereira;David Mazumder;Diego Pacheco;Mala Murthy

10.1101/221044 — neuroscience — Posted on 2017-11-17

6 Synaptic m6A Epitranscriptome Reveals Functional Partitioning of Localized Transcripts for Dynamic Tripartite Synapse Modulation

Daria Merkurjev;Wan-Ting Hong;Kei Iida;Belinda Goldie;Hitoshi Yamaguti;Ikumi Oomoto;Takayuki Ohara;Shin-ya Kawaguchi;Tomoo Hirano;Kelsey C Martin;Matteo Pellegrini;Dan O Wang

10.1101/221374 — neuroscience — Posted on 2017-11-17

7 Loss of the intellectual disability and autism gene Cc2d1a and its homolog Cc2d1b differentially affect spatial memory, anxiety, and hyperactivity

Marta Zamarbide;Adam W Oaks;Heather L Pond;Julia S Adelman;M. Chiara Manzini

10.1101/222638 — neuroscience — Posted on 2017-11-21

8 Value generalization in human avoidance learning

Agnes Norbury;Trevor W Robbins;Ben Seymour

10.1101/223149 — neuroscience — Posted on 2017-11-21

9 Comparing neurotransmitter metabolism in the brain of patients with symptomatic and aysmptomatic Alzheimer’s disease and healthy individuals

Snowden, S. G.; Ebshiana, A.; Hye, A.; Yang, A.; Olga, P.; Richard, O.; John, T.; Cristina, L.-Q.; Madhav, T.

10.1101/220699 — neuroscience — Posted on 2017-11-17

10 Effect of dihydrolipoamide dehydrogenase (dld-1) on human tau phosphorylation in a C. elegans model of Alzheimer’s Disease

Ahmad, W.

10.1101/220442 — neuroscience — Posted on 2017-11-17

11 Defining Depression Cohorts Using the EHR: Multiple Phenotypes Based on ICD-9 Codes and Medication Orders

Ingram, W. M.; Baker, A. M.; Brown, J. P.; Goes, F. S.; Zandi, P. P.; Larson, S.

10.1101/227561 — epidemiology — Posted on 2017-11-30

12 Optimal Vaccination of a General Population Network via Genetic Algorithms

Sanders, L.

10.1101/227116 — epidemiology — Posted on 2017-11-30

13 Genome-based transmission modeling separates imported tuberculosis from recent transmission within an immigrant population

Ayabina, D.; Ronning, J. O.; Alfsnes, K.; Debech, N.; Brynildsrud, O. B.; Arnesen, T.; Norheim, G.; Mengshoel, A.-T.; Rykkvin, R.; Dahle, U. R.; Colijn, C.; Eldholm, V.

10.1101/226662 — epidemiology — Posted on 2017-11-30

14 Visual Representation of Experimental Protocols

Scott-Brown, J.; Papachristodoulou, A.

10.1101/226852 — synthetic biology — Posted on 2017-11-30

15 A rhamnose-inducible system for precise and temporal control of gene expression in cyanobacteria

Kelly, C. L.; Hitchcock, A.; Torres-Mendez, A.; Heap, J.

10.1101/227355 — synthetic biology — Posted on 2017-11-30

16 Formin3 regulates dendritic architecture via microtubule stabilization and is required for somatosensory nociceptive behavior

Das, R.; Letcher, J. M.; Harris, J. M.; Foldi, I.; Nanda, S.; Bobo, H. M.; Mihaly, J.; Ascoli, G. A.; Cox, D. N.

10.1101/227348 — neuroscience — Posted on 2017-11-30

17 Serotonin 5-HT1A receptor binding and self-transcendence in healthy control subjects - a replication study using Bayesian hypothesis testing

Griffioen, G.; Matheson, G. J.; Cervenka, S.; Farde, L.; Borg, J.

10.1101/226092 — neuroscience — Posted on 2017-11-30

18 A clustering neural network model of insect olfaction

Pehlevan, C.; Genkin, A.; Chklovskii, D. B.

10.1101/226746 — neuroscience — Posted on 2017-11-30

19 An open resource for nonhuman primate imaging

Milham, M.; Ai, L.; Koo, B.; Xu, T.; Balezeau, F.; Baxter, M. G.; Croxson, P. L.; Damatac, C. G.; Harel, N.; Freiwald, W.; Griffiths, T. D.; Everling, S.; Jung, B.; Kastner, S.; Leopold, D. A.; Mars, R. B.; Menon, R. S.; Messinger, A.; Morrison, J. H.; Nacef, J.; Nagy, J.; Rios, M. O.; Petkov, C. I.; Pinsk, M.; Poirier, C.; Rajimehr, R.; Rushworth, M. F.; Russ, B. E.; Schmid, M.; Schwiedrzik, C. M.; Sallet, J.; Seidlitz, J.; Ungerleider, L.; Thiele, A.; Tsao, D.; Yacoub, E.; Ye, F.; Zarco, W.; Margulies, D. S.; Schroeder, C. E.

10.1101/227462 — neuroscience — Posted on 2017-11-30

20 Peripatric speciation associated with genome expansion and female-biased sex ratios in the moss genus Ceratodon

Nieto-Lugilde, M.; Werner, O.; McDaniel, S. F.; Koutecky, P.; Kucera, J.; Rizk, S. M.; Ros, R. M.

10.1101/227280 — molecular biology — Posted on 2017-11-30

21 Cytomegalovirus infection is a risk factor for TB disease in Infants

Muller, J.; Matsumiya, M.; Snowden, M. A.; Bernard, B.; Satti, I.; Harris, S. A.; Tanner, R.; O'Shea, M. K.; Stockdale, L.; Marsay, L.; Chomka, A.; Harrington-Kandt, R.; Manjaly Thomas, Z.-R.; Naranbhai, V.; Stylianou, E.; Kimbung Mbandi, S.; Hatherill, M.; Hussey, G.; Mahomed, H.; Tameris, M.; McClain, J. B.; Evans, T. G.; Hanekom, W. A.; Scriba, T. J.; McShane, H.; Fletcher, H. A.

10.1101/222646 — immunology — Posted on 2017-11-30

22 Actin Redundancy in Chlamydomonas is Required for Flagellar Protein Synthesis and Gating

Jack, B.; Mueller, D. M.; Fee, A. C.; Tetlow, A.; Avasthi, P.

10.1101/227553 — cell biology — Posted on 2017-11-30

23 High resolution genetic mapping of causal regulatory interactions in the human genome

Kumasaka, N.; Knights, A.; Gaffney, D.

10.1101/227389 — genomics — Posted on 2017-11-30

24 Promoter boundaries for the luxCDABE and betIBA-proXWV operons in Vibrio harveyi defined by the method RAIL: Rapid Arbitrary PCR Insertion Libraries

Hustmyer, C. M.; Simpson, C. A.; Olney, S. G.; Bochman, M. L.; van Kessel, J. C.

10.1101/227371 — molecular biology — Posted on 2017-11-30

25 Oxford Nanopore sequencing in a research-based undergraduate course

Zeng, Y.; Martin, C. H.

10.1101/227439 — genomics — Posted on 2017-11-30

26 Recombination of ecologically and evolutionarily significant loci maintains genetic cohesion in the Pseudomonas syringae species complex

Dillion, M. M.; Thakur, S.; Almeida, R. N.; Guttman, D. S.

10.1101/227413 — genomics — Posted on 2017-11-30

27 BLINK: A Package for Next Level of Genome Wide Association Studies with Both Individuals and Markers in Millions

Huang, M.; Liu, X.; Zhou, Y.; Summers, R. M.; Zhang, Z.

10.1101/227249 — genomics — Posted on 2017-11-30

28 A genome-wide resource for high-throughput genomic tagging of yeast ORFs

Meurer, M.; Duan, Y.; Sass, E.; Kats, I.; Herbst, K.; Buchmuller, B. C.; Dederer, V.; Huber, F.; Kirrmaier, D.; Stefl, M.; Van Laer, K.; Dick, T. P.; Lemberg, M. K.; Khmelinskii, A.; Levy, E. D.; Knop, M.

10.1101/226811 — genomics — Posted on 2017-11-30

29 Introgression of a block of genome under infinitesimal selection

Sachdeva, H.; Barton, N. H.

10.1101/227082 — genetics — Posted on 2017-11-30

30 Rice blast resistance gene Pii is controlled by a pair of NBS-LRR genes Pii-1 and Pii-2

Takagi, H.; Abe, A.; Uemura, A.; Oikawa, K.; Utsushi, H.; Yaegashi, H.; Kikuchi, H.; Shimizu, M.; Abe, Y.; Kanzaki, H.; Saitoh, H.; Terauchi, R.; Fujisaki, K.

10.1101/227132 — genetics — Posted on 2017-11-30

31 Constrained Instruments and their Application to Mendelian Randomization with Pleiotropy

Jiang, L.; Oualkacha, K.; Didelez, V.; Ciampi, A.; Rosa, P.; Benedet, A. L.; Mathotaarachchi, S. S.; Richards, B.; Greenwood, C. M. T.

10.1101/227454 — genetics — Posted on 2017-11-30

32 Hybrid Songbirds are Deficient in Learning and Memory

McQuillan, M. A.; Roth, T. C.; Huynh, A. V.; Rice, A. M.

10.1101/227298 — evolutionary biology — Posted on 2017-11-30

33 No evidence for correlations between handgrip strength and sexually dimorphic acoustic properties of voices

Han, C.; Wang, H.; Fasolt, V.; Hahn, A.; Holzleitner, I. J.; DeBruine, L.; Feinberg, D.; Jones, B.

10.1101/227165 — evolutionary biology — Posted on 2017-11-30

34 The use of salivary α-amylase as an evolutionary solution to host selection in parasitoids

Bichang'a, G.; Da Lage, J.-L.; Mailhan, C.-M.; Marion-Poll, F.; Capdevielle-Dulac, C.; Zivy, M.; Balliau, T.; Le Ru, B.; Kaiser-Arnauld, L.; Juma, G.; Maina, E.; Calatayud, P.-a.

10.1101/227173 — evolutionary biology — Posted on 2017-11-30

35 The interplay between facilitation and habitat type drive spatial vegetation patterns in global drylands

Berdugo, M.; Soliveres, S.; Kefi, S.; Maestre, F. T.

10.1101/227330 — ecology — Posted on 2017-11-30

36 Physico-chemical properties of co-formulation of insulin with pramlintide

Silva, D. C.; Lima, L. M.

10.1101/227363 — biophysics — Posted on 2017-11-30

37 Classifying cells with Scasat - a tool to analyse single-cell ATAC-seq

Baker, S. M.; Rogerson, C.; Hayes, A.; Sharrocks, A. D.; Rattray, M.

10.1101/227397 — bioinformatics — Posted on 2017-11-30

38 Improving the annotation of the Heterorhabditis bacteriophora genome

McLean, F.; Berger, D.; Laetsch, D.; Schwartz, H.; Blaxter, M.

10.1101/225904 — bioinformatics — Posted on 2017-11-30

39 The GCTx format and cmap{Py, R, M} packages: resources for the optimized storage and integrated traversal of dense matrices of data and annotations

Enache, O. M.; Lahr, D. L.; Natoli, T. E.; Litichevskiy, L.; Wadden, D.; Flynn, C.; Gould, J.; Asiedu, J. K.; Narayan, R.; Subramanian, A.

10.1101/227041 — bioinformatics — Posted on 2017-11-30

40 In vivo multiphoton fluorescence imaging with polymer dots

Hassan, A. M.; Wu, X.; Jarrett, J. W.; Xu, S.; Miller, D. R.; Yu, J.; Perillo, E. P.; Liu, Y.-L.; Chiu, D. T.; Yeh, H.-C.; Dunn, A. K.

10.1101/227488 — bioengineering — Posted on 2017-11-30

41 Catalytic potential and disturbance rejection of glycolytic kinases in the human red blood cell

Yurkovich, J. T.; Alcantar, M. A.; Haiman, Z. B.; Palsson, B. O.

10.1101/227058 — systems biology — Posted on 2017-11-30

42 Biological Self-organisation and Markov blankets

Palacios, E. R.; Razi, A.; Parr, T.; Kirchhoff, M.; Friston, K.

10.1101/227181 — systems biology — Posted on 2017-11-30

43 Characterisation of the pathogenicity of strains of Pseudomonas syringae towards cherry and plum

Hulin, M. T.; Mansfield, J. W.; Brain, P.; Xu, X.; Jackson, R. W.; Harrison, R.

10.1101/227223 — plant biology — Posted on 2017-11-30

44 Differential representation of articulatory gestures and phonemes in motor, premotor, and inferior frontal cortices

Mugler, E. M.; Tate, M. C.; Livescu, K.; Templer, J. W.; Goldrick, M. A.; Slutzky, M. W.

10.1101/220723 — neuroscience — Posted on 2017-11-30

45 Tau hyperphosphorylation on T217 in cerebrospinal fluid is specifically associated to amyloid-β pathology

Barthelemy, N. R.; Bateman, R. J.; Marin, P.; Becher, F.; Sato, C.; Lehmann, S.; Gabelle, A.

10.1101/226977 — neuroscience — Posted on 2017-11-30

46 Laminar-specific cortical dynamics in human visual and sensorimotor cortices

Bonaiuto, J. J.; Meyer, S. S.; Little, S.; Rossiter, H.; Callaghan, M. F.; Dick, F.; Barnes, G. R.; Bestmann, S.

10.1101/226274 — neuroscience — Posted on 2017-11-30

47 On the Impact of Interhemispheric White Matter: Age, Executive Functioning, and Dedifferentiation in the Frontal Lobes

Waters, A. B.; Sawyer, K. S.; Gansler, D. A.

10.1101/226845 — neuroscience — Posted on 2017-11-30

48 Altering brain dynamics with transcranial random noise stimulation

van der Groen, O.; Wenderoth, N.; Mattingley, J.

10.1101/227140 — neuroscience — Posted on 2017-11-30

49 Rule Activation and Ventromedial Prefrontal Engagement Support Accurate Stopping in Self-Paced Learning

O'Bryan, S.; Walden, E.; Serra, M. J.; Davis, T.

10.1101/169110 — neuroscience — Posted on 2017-11-30

50 Differential temporal dynamics during visual imagery and perception

Dijkstra, N.; Mostert, P.; de Lange, F.; Bosch, S. E.; van Gerven, M.

10.1101/226217 — neuroscience — Posted on 2017-11-30

51 Counterfactual reasoning underlies the learning of priors in decision making

Zylberberg, A.; Wolpert, D. M.; Shadlen, M. N.

10.1101/227421 — neuroscience — Posted on 2017-11-30

52 Common variant burden contributes significantly to the familial aggregation of migraine in 1,589 families

Gormley, P.; Kurki, M. I.; Hiekkala, M. E.; Veerapen, K.; Häppölä, P.; Mitchell, A.; Lal, D.; Palta, P.; Surakka, I.; Kaunisto, M. A.; Hämäläinen, E.; Vepsäläinen, S.; Havanka, H.; Harno, H.; Ilmavirta, M.; Nissilä, M.; Säkö, E.; Sumelahti, M.-L.; Liukkonen, J.; Sillanpää, M.; Metsähonkala, L.; Jousilahti, P.; Anttila, V.; Salomaa, V.; Artto, V.; Färkkilä, M.; 23andMe Research Team, ; The International Headache Genetics Consortium, ; Runz, H.; Daly, M. J.; Neale, B.

10.1101/226985 — genetics — Posted on 2017-11-30

53 Assessment of the performance of different hidden Markov models for imputation in animal breeding

Whalen, A.; Gorjanc, G.; Ros-Freixedes, R.; Hickey, J. M.

10.1101/227157 — genetics — Posted on 2017-11-30

54 Gene Expression Distribution Deconvolution in Single Cell RNA Sequencing

Wang, J.; Huang, M.; Torre, E.; Dueck, H.; Shaffer, S.; Murray, J.; Raj, A.; Li, M.; Zhang, N. R.

10.1101/227033 — genetics — Posted on 2017-11-30

55 Early-exposure to new sex pheromone blend alters mate preference in female butterflies and in their offspring

Dion, E.; Pui, L. X.; Monteiro, A.

10.1101/214635 — evolutionary biology — Posted on 2017-11-30

56 Rapid evolution of gained essential developmental functions of a young gene via interactions with other essential genes

Lee, Y. C. G.; Ventura, I. M.; Rice, G. R.; Chen, D.-Y.; Long, M.

10.1101/226936 — evolutionary biology — Posted on 2017-11-30

57 Gene regulatory network rewiring by an adaptively evolving microRNA cluster in Drosophila

Lyu, Y.; Liufu, Z.; Xiao, J.; Chen, Y.; Wu, C.-I.; Tang, T.

10.1101/227314 — evolutionary biology — Posted on 2017-11-30

58 Timescales of influenza A/H3N2 antibody dynamics

Kucharski, A.; Lessler, J.; Cummings, D.; Riley, S.

10.1101/183111 — epidemiology — Posted on 2017-11-30

59 Nasal and aerosol shedding of infectious influenza virus - a community based study

Yan, J.; Grantham, M.; Pantelic, J.; Bueno de Mesquita, P. J.; Albert, B.; Liu, F.; Ehrman, S.; Milton, D. K.; EMIT Consortium,

10.1101/194985 — epidemiology — Posted on 2017-11-30

60 Review of UNAIDS national estimates of men who have sex with men, gay dating application users, and 90-90-90 data

Granich, R.; Gupta, S.; Garner, A.; Howell, S.

10.1101/186163 — epidemiology — Posted on 2017-11-30

61 Single cell RNA-seq and ATAC-seq indicate critical roles of Isl1 and Nkx2-5 for cardiac progenitor cell transition states and lineage settlement

Jia, G.; Preussner, J.; Guenther, S.; Yuan, X.; Yekelchyk, M.; Kuenne, C.; Looso, M.; Zhou, Y.; Braun, T.

10.1101/210930 — developmental biology — Posted on 2017-11-30

62 Force-dependent ligand sensing enables αVβ3 integrin to differentiate between fibronectin and high-affinity ligands

Bachmann, M.; Schäfer, M.; Weissenbruch, K.; Mykuliak, V.; Heiser, L.; Franz, C. M.; Hytönen, V.; Wehrle-Haller, B.; Bastmeyer, M.

10.1101/200493 — cell biology — Posted on 2017-11-30

63 Decrease of Nibrin expression in chronic hypoxia is associated with hypoxia-induced chemoresistance in medulloblastoma cells

Cowman, S.; Fan, Y. N.; Pizer, B.; See, V.

10.1101/227207 — cell biology — Posted on 2017-11-30

64 TelNet - a database for human and yeast genes involved in telomere maintenance

Braun, D. M.; Chung, I.; Kepper, N.; Deeg, K. I.; Rippe, K.

10.1101/130153 — cancer biology — Posted on 2017-11-30

65 Aberrant splicing in B-cell acute lymphoblastic leukemia

Black, K. L.; Naqvi, A. S.; Hayer, K. E.; Yang, S.; Gillespie, E.; Bagashev, A.; Pillai, V.; Tasian, S.; Gazzara, M. R.; Carroll, M.; Taylor, D.; Lynch, K. W.; Barash, Y.; Thomas-Tikhonenko, A.

10.1101/225136 — cancer biology — Posted on 2017-11-30

66 An Essential Role for Argonaute 2 in EGFR-KRAS Signaling in Pancreatic Cancer Development

Shankar, S.; Tien, J.; Siebenaler, R. F.; Dommeti, V. L.; Zelenka-Wang, S.; Juckette, K. M.; Xu, A.; Mody, M.; Goodrum, A.; Tsaloff, G.; Apel, I. J.; Wang, L.; Siddiqui, J.; Shi, J.; Kumar-Sinha, C.; Chinnaiyan, A. M.

10.1101/227264 — cancer biology — Posted on 2017-11-30

67 Biomolecular simulations under realistic macroscopic salt conditions

Ross, G. A.; Rustenburg, A. S.; Grinaway, P. B.; Fass, J.; Chodera, J. D.

10.1101/226001 — biophysics — Posted on 2017-11-30

68 Statistical methods for large ensemble of super-resolution stochastic single particle trajectories

Hoze, N.; holcman, d.

10.1101/227090 — biophysics — Posted on 2017-11-30

69 Generalization and search in risky environments

Schulz, E.; Wu, C. M.; Huys, Q. J. M.; Krause, A.; Speekenbrink, M.

10.1101/227322 — animal behavior and cognition — Posted on 2017-11-30

70 SNPTB: nucleotide variant identification and annotation in Mycobacterium tuberculosis genomes

Gupta, A.

10.1101/227066 — bioinformatics — Posted on 2017-11-30

71 A linear-time algorithm to sample the dual-birth model

Moshiri, N.

10.1101/226423 — bioinformatics — Posted on 2017-11-30

72 Single-molecule DNA unzipping reveals asymmetric modulation of a transcription factor by its binding site sequence and context

Rudnizky, S.; Khamis, H.; Malik, O.; Squires, A.; Meller, A.; Melamed, P.; Kaplan, A.

10.1101/188458 — biophysics — Posted on 2017-11-30

73 Quinary structure kinetically controls protein function and dysfunction

Khan, T.; Kandola, T.; Wu, J.; Ketter, E.; Venkatesan, S.; Lange, J. J.; Rodriguez Gama, A.; Box, A.; Unruh, J. R.; Cook, M.; Halfmann, R.

10.1101/205690 — biophysics — Posted on 2017-11-30

74 Dopaminergic Modulation Of Hemodynamic Signal Variability And The Functional Connectome During Cognitive Performance

Alavash, M.; Lim, S.-J.; Thiel, C.; Sehm, B.; Deserno, L.; Obleser, J.

10.1101/130021 — neuroscience — Posted on 2017-11-30

75 Non-invasive laminar inference with MEG: Comparison of methods and source inversion algorithms

Bonaiuto, J. J.; Rossiter, H. E.; Meyer, S. S.; Adams, N.; Little, S.; Callaghan, M. F.; Dick, F.; Bestmann, S.; Barnes, G. R.

10.1101/147215 — neuroscience — Posted on 2017-11-30

76 Optimizing survey methods for spiders and harvestmen assemblages in an Amazonian upland forest

Tourinho, A. L.; Dias, S. C.; Lo Man Hung, N.; Pinto-da-Rocha, R.; Baccaro, F. B.; Bonaldo, A. B.

10.1101/093740 — ecology — Posted on 2017-11-30

77 Integrative DNA copy number detection and genotyping from sequencing and array-based platforms

Zhou, Z.; Wang, W.; Wang, L.-S.; Zhang, N.

10.1101/172700 — bioinformatics — Posted on 2017-11-30

78 Comparative genomics approaches accurately predict deleterious variants in plants

Kono, T. J. Y.; Lei, L.; Shih, C.-H.; Hoffman, P. J.; Morrell, P. L.; Fay, J. C.

10.1101/112318 — bioinformatics — Posted on 2017-11-30

79 THiCweed: fast, sensitive detection of sequence features by clustering big data sets

Agrawal, A.; Sambare, S. V.; Narlikar, L.; Siddharthan, R.

10.1101/104109 — bioinformatics — Posted on 2017-11-30

80 Reciprocal Disruptions in Thalamic and Hippocampal Resting-State Functional Connectivity in Youth with 22q11.2 Deletions

Schleifer, C. H.; Lin, A.; Kushan, L.; Ji, J. L.; Yang, G.; Bearden, C. E.; Anticevic, A.

10.1101/226951 — neuroscience — Posted on 2017-11-29

81 Sniff-invariant intensity perception using olfactory bulb coding of inhalation dynamics

Jordan, R.; Kollo, M.; Schaefer, A. T.

10.1101/226969 — neuroscience — Posted on 2017-11-29

82 Soluble amyloid-beta buffering by plaques in Alzheimer disease dementia versus high-pathology controls

Esparza, T.; Gangolli, M.; Cairns, N. J.; Brody, D. L.

10.1101/227009 — neuroscience — Posted on 2017-11-29

83 Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche

Sosa, E.; Chen, D.; Rojas, E. J.; Hennebold, J.; Peters, K.; Wu, Z.; Lam, T. N.; Mitchell, J.; Tailor, R.; Meistrich, M.; Orwig, K.; Shetty, G.; Clark, A. T.

10.1101/226506 — developmental biology — Posted on 2017-11-29

84 The paradoxical sustainability of periodic migration and habitat destruction

Tan, Z. X.; Cheong, K. H.

10.1101/226589 — ecology — Posted on 2017-11-29

85 CRISPR-Cas12a target binding unleashes single-stranded DNase activity

Chen, J. S.; Ma, E.; Harrington, L. B.; Tian, X.; Doudna, J. A.

10.1101/226993 — biochemistry — Posted on 2017-11-29

86 Inhibition of the Platelet-activating factor receptor for the treatment of Amyotrophic Lateral Sclerosis?

Briones, M. R.; Snyder, A. M.; Neely, E. B.; Connor, J. R.; Broach, J. R.

10.1101/224030 — neuroscience — Posted on 2017-11-29

87 Community-driven data analysis training for biology

Batut, B.; Hiltemann, S.; Bagnacani, A.; Baker, D.; Bhardwaj, V.; Blank, C.; Bretaudeau, A.; Gueguen, L.; Cech, M.; Chilton, J.; Clements, D.; Doppelt-Azeroual, O.; Erxleben, A.; Freeberg, M.; Gladman, S.; Hoogstrate, Y.; Hotz, H.-R.; Houwaart, T.; Jagtap, P.; Lariviere, D.; Le Corguille, G.; Manke, T.; Mareuil, F.; Ramirez, F.; Ryan, D.; Sigloch, F.; Soranzo, N.; Wolff, J.; Videm, P.; Wolfien, M.; Wubuli, A.; Yusuf, D.; Backofen, R.; Nekrutenko, A.; Grüning, B.

10.1101/225680 — bioinformatics — Posted on 2017-11-29

88 Enumerating all possible biosynthetic pathways from metabolic networks

Ravikrishnan, A.; Nasre, M.; Raman, K.

10.1101/226795 — systems biology — Posted on 2017-11-29

89 ShuTu: Open-Source Software for Efficient and Accurate Reconstruction of Dendritic Morphology

Jin, D. Z.; Zhao, T.; Hunt, D.; Pearcy, R.; Hsu, C.-L.; Spruston, N.

10.1101/226548 — neuroscience — Posted on 2017-11-29

90 Neutrophil adhesion in brain capillaries contributes to cortical blood flow decreases and impaired memory function in a mouse model of Alzheimer’s disease

Cruz Hernandez, J. C.; Bracko, O.; Kersbergen, C. J.; Muse, V.; Haft-Javaherian, M.; Berg, M.; Park, L.; Vinarcsik, L. K.; Ivasyk, I.; Kang, Y.; Cortes-Canteli, M.; Peyrounette, M.; Doyeux, V.; Smith, A.; Zhou, J.; Otte, G.; Beverly, J. D.; Davenport, E.; Davit, Y.; Strickland, S.; Iadecola, C.; Lorthois, S.; Nishimura, N.; Schaffer, C. B.

10.1101/226886 — neuroscience — Posted on 2017-11-29

91 Transcriptome-wide analysis of the functional intronome using spliceosome profiling

Chen, W.; Moore, J.; Ozadam, H.; Shulha, H. P.; Rhind, N.; Weng, Z.; Moore, M. J.

10.1101/226894 — genomics — Posted on 2017-11-29

92 Penetrance of polygenic obesity susceptibility loci across the body mass index distribution: an update on scaling effects.

Abadi, A.; Alyass, A.; Robiou du Pont, S.; Bolker, B.; Singh, P.; Mohan, V.; Diaz, R.; Engert, J. C.; Gerstein, H. C.; Anand, S. S.; Meyre, D.

10.1101/225128 — genetics — Posted on 2017-11-29

93 Niche separation increases with genetic distance among bloom-forming cyanobacteria

Tromas, N.; Taranu, Z. E.; Martin, B. D.; Willis, A.; Fortin, N.; Greer, C. W.; Shapiro, B. J.

10.1101/226860 — ecology — Posted on 2017-11-29

94 Foliar pathogens of California grasses infect multiple hosts: implications for grassland diversity

Spear, E. R.; Mordecai, E. A.

10.1101/226928 — ecology — Posted on 2017-11-29

95 Multiple inputs ensure yeast cell size homeostasis during cell cycle progression

Garmendia, C.; Tassy, O.; Matifas, A.; Molina, N.; Charvin, G.

10.1101/226803 — cell biology — Posted on 2017-11-29

96 Assessing the Gene Regulatory Landscape in 1,188 Human Tumors

Calabrese, C.; Lehmann, K.-V.; Urban, L.; Liu, F.; Erkek, S.; Fonseca, N.; Kahles, A.; Kilpinen-Barrett, L. H.; Markowski, J.; PCAWG-3, ; Waszak, S.; Korbel, J.; Zhang, Z.; Brazma, A.; Raetsch, G.; Schwarz, R.; Stegle, O.

10.1101/225441 — cancer biology — Posted on 2017-11-29

97 Structure of lekking courts of male White-bearded Manakins (Manacus manacus) is linked to their attractiveness

Tokarev, K.; van der Hoek, Y.

10.1101/226944 — animal behavior and cognition — Posted on 2017-11-29

98 Conformational control of translation termination on the 70S ribosome

Svidritskiy, E.; Korostelev, A. A.

10.1101/226837 — biochemistry — Posted on 2017-11-29

99 Paramecium Learning: New Insights and Modifications

Alipour, A.; Dorvash, M.; Yeganeh, Y.; Hatam, G.

10.1101/225250 — animal behavior and cognition — Posted on 2017-11-29

100 Expecting the Unexpected: Base-rate Neglect is Driven by Neural Activation of Common Cues

O'Bryan, S. R.; Worthy, D. A.; Livesey, E. J.; Davis, T.

10.1101/130716 — neuroscience — Posted on 2017-11-29

101 A quantitative PCR based environmental DNA assay for detecting Atlantic salmon (Salmo salar L.)

Atkinson, S.; Carlsson, J. E. L.; Ball, B.; Egan, D.; Kelly-Quinn, M.; Whelan, K.; Carlsson, J.

10.1101/226829 — genetics — Posted on 2017-11-29

102 Tn-Core: context-specific reconstruction of core metabolic models using Tn-seq data

diCenzo, G.; Mengoni, A.; Fondi, M.

10.1101/221325 — systems biology — Posted on 2017-11-29

103 Rehabilitation promotes the recovery of distinct functional and structural features of healthy neuronal networks after stoke

Allegra Mascaro, A. L.; Conti, E.; Lai, S.; Di Giovanna, A. P.; Spalletti, C.; Alia, C.; Quarta, E.; Panarese, A.; Sacconi, L.; Micera, S.; Caleo, M.; Pavone, F. S.

10.1101/141697 — neuroscience — Posted on 2017-11-29

104 Listeria monocytogenes virulence factors are secreted in biologically active Extracellular Vesicles

Coelho, C.; Brown, L.; Maryam, M.; Burnet, M. C.; Kyle, J. E.; Heyman, H. M.; Vij, R.; Ramirez, J.; Prados-Rosales, R.; Lauvau, G.; Nakayasu, E. S.; Brady, N. R.; Brady, A.; Coppens, I.; Casadevall, A.

10.1101/210906 — microbiology — Posted on 2017-11-29

105 The miR-96/RARγ signaling axis governs androgen signaling and prostate cancer progression

Long, M. D.; Singh, P. K.; Russell, J. R.; Llimos, G.; Rosario, S.; Rizvi, A.; Withers, H.; van den Berg, P. R.; Kirk, J.; Sucheston-Campbell, L. E.; Smiraglia, D. J.; Campbell, M. J.

10.1101/198465 — cancer biology — Posted on 2017-11-29

106 The Wisconsin Registry for Alzheimer’s Prevention: A Review of findings and current directions

Johnson, S. C.; Koscik, R. L.; Jonaitis, E. M.; Clark, L. R.; Mueller, K. D.; Berman, S. E.; Bendlin, B. B.; Engelman, C. D.; Okonkwo, O. C.; Hogan, K. J.; Asthana, S.; Carlsson, C. M.; Hermann, B. P.; Sager, M. A.

10.1101/206839 — neuroscience — Posted on 2017-11-29

107 Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins

Wang, Y.; Karlsson, R.; Lampa, E.; Zhang, Q.; Hedman, A. K.; Almgren, M.; Almqvist, C.; McRae, A. F.; Marioni, R.; Ingelsson, E.; Visscher, P. M.; Deary, I. J.; Lind, L.; Morris, T.; Beck, S.; Pedersen, N. L.; Hägg, S.

10.1101/226266 — genetics — Posted on 2017-11-29

108 The contributions of the actin machinery to endocytic membrane bending and vesicle formation

Picco, A.; Kukulski, W.; Manenschijn, H. E.; Specht, T.; Briggs, J. A. G.; Kaksonen, M.

10.1101/172072 — cell biology — Posted on 2017-11-29

109 Single-Molecule Peptide Fingerprinting

van Ginkel, J.; Filius, M.; Szczepaniak, M.; Tulinksi, P.; Meyer, A. S.; Joo, C.

10.1101/226712 — biophysics — Posted on 2017-11-29

110 Controllability in an islet specific regulatory network identifies the transcriptional factor NFATC4, which regulates Type 2 Diabetes associated genes

Sharma, A.; Halu, A.; Decano, J. L.; Menche, J.; Liu, Y.-Y.; Prasad, R. B.; Fadista, J.; Santolini, M.; Padi, M.; Weiss, S. T.; Vidal, M.; Silverman, E. K.; Aikawa, M.; Barabasi, A.-L.; Groop, L.; Loscalzo, J.

10.1101/226456 — systems biology — Posted on 2017-11-29

111 A design framework and exemplar metrics for FAIRness

Wilkinson, M. D.; Sansone, S.-A.; Schultes, E.; Doorn, P.; Bonino da Silva Santos, L. O.; Dumontier, M.

10.1101/225490 — scientific communication and education — Posted on 2017-11-29

112 UV-Induced Keratin 1 Proteolysis Mediates UV-Induced Skin Damage

Zhang, M.; Maharjan, D. T.; He, H.; Li, Y.; Yan, W.; Yan, W.; Zhu, Y.; Ying, W.

10.1101/226308 — pathology — Posted on 2017-11-29

113 And the best task is ...? Using Task potency to infer task specificity

Chauvin, R.; Mennes, M.; Llera Arenas, A.; Buitelaar, J.; Beckmann, C.

10.1101/111187 — neuroscience — Posted on 2017-11-29

114 Network supporting contextual fear learning after dorsal hippocampal damage has increased dependence on retrosplenial cortex

Coelho, C. A. O.; Ferreira, T. L.; Soares, J. C. K.; Sato, J. R.; Oliveira, M. G. M.

10.1101/209866 — neuroscience — Posted on 2017-11-29

115 Prioritized memory access explains planning and hippocampal replay

Mattar, M. G.; Daw, N. D.

10.1101/225664 — neuroscience — Posted on 2017-11-29

116 Identifying the in vivo cellular correlates of antipsychotic drugs

Joshi, R.; PANICKER, M.

10.1101/226050 — neuroscience — Posted on 2017-11-29

117 Altered sensitivity to motion of area MT neurons following long-term V1 lesions

Hagan, M. A.; Chaplin, T. A.; Huxlin, K. R.; Rosa, M. G. P.; Lui, L. L.

10.1101/226571 — neuroscience — Posted on 2017-11-29

118 Rapid, noninvasive, and unsupervised detection of sleep/wake using piezoelectric monitoring for pharmacological studies in narcoleptic mice

Black, S. W.; Sun, J. D.; Laihsu, A.; Kimura, N.; Santiago, P.; Donohue, K. D.; O'Hara, B. F.; Bersot, R.; Humphries, P. S.

10.1101/226522 — neuroscience — Posted on 2017-11-29

119 Loss of Wt1 in the murine spinal cord alters interneuron composition and locomotion

Schnerwitzki, D.; Perry, S.; Ivanova, A.; Caixeta, F. V.; Cramer, P.; Guenther, S.; Weber, K.; Tafreshiha, A.; Becker, L.; Vargas Panesso, I. L.; Klopstock, T.; Hrabe de Angelis, M.; Schmidt, M.; Kullander, K.; Englert, C.

10.1101/226316 — neuroscience — Posted on 2017-11-29

120 Identification and Targeting of Cortical Ensembles

Carrillo-Reid, L.; Han, S.; Taralova, E.; Jebara, T.; Yuste, R.

10.1101/226514 — neuroscience — Posted on 2017-11-29

121 Learning a neural response metric for retinal prosthesis

Shah, N. P.; Madugula, S.; Chichilnisky, E. J.; Singer, Y.; Shlens, J.

10.1101/226530 — neuroscience — Posted on 2017-11-29

122 The Vibrio cholerae Type VI Secretion System Can Modulate Host Intestinal Mechanics to Displace Commensal Gut Bacteria

Logan, S. L.; Thomas, J.; Yan, J.; Baker, R. P.; Shields, D. S.; Xavier, J. B.; Hammer, B. K.; Parthasarathy, R.

10.1101/226472 — microbiology — Posted on 2017-11-29

123 Increased usage of antiseptics is associated with reduced susceptibility in clinical isolates of S. aureus

Hardy, K.; Sunnucks, K.; Gil, H.; Shabir, S.; Trampari, E.; Hawkey, P.; Webber, M. A.

10.1101/226738 — microbiology — Posted on 2017-11-29

124 A new sequence logo plot to highlight enrichment and depletion

Dey, K. K.; Xie, D.; Stephens, M.

10.1101/226597 — genetics — Posted on 2017-11-29

125 The asexual genome of Drosophila

Schiffels, S.; Mustonen, V.; Lässig, M.

10.1101/226670 — genetics — Posted on 2017-11-29

126 Collapse and rescue of cooperation in evolving dynamic networks

Akcay, E.

10.1101/226563 — evolutionary biology — Posted on 2017-11-29

127 Effective polyploidy causes phenotypic delay and influences bacterial evolvability

Sun, L.; Alexander, H. K.; Bogos, B.; Kiviet, D. J.; Ackermann, M.; Bonhoeffer, S.

10.1101/226654 — evolutionary biology — Posted on 2017-11-29

128 Time calibrated tree of Dioscorea (Dioscoreaceae) indicated four origins of yams in the Neotropics since Eocene

Couto, R. S.; Martins, A.; Bolson, M.; Lopes, R. C.; Smidt, E. C.; Braga, J. M. A.

10.1101/224790 — evolutionary biology — Posted on 2017-11-29

129 The paradoxical sustainability of periodic migration and habitat destruction

Tan, Z. X.; Cheong, K. H.

10.1101/226589 — ecology — Posted on 2017-11-29

130 An adaptable chromosome preparation methodology for use in invertebrate research organisms

Guo, L.; Accorsi, A.; He, S.; Guerrero-Hernandez, C.; Sivagnanam, S.; McKinney, S.; Gibson, M.; Sanchez Alvarado, A.

10.1101/226084 — developmental biology — Posted on 2017-11-29

131 CYRI (FAM49) proteins are local inhibitors of Scar/WAVE induced lamellipodia that bind directly to active Rac1

Fort, L.; Batista, J.; Thomason, P. A.; Spence, H. J.; Greaves, J.; Martin, K. J.; Anderson, K. I.; Brown, P.; Lilla, S.; Neilson, M. P.; Tafelmeyer, P.; Zanivan, S.; Ismail, S.; Tomkinson, N. C. O.; Chamberlain, L. H.; Insall, R. H.; Machesky, L. M.

10.1101/164905 — cell biology — Posted on 2017-11-29

132 Electrophysiological properties of human β-cell lines EndoC-βH1 and -βH2 conform with human β-cells

Hastoy, B.; Godazgar, M.; Clark, A.; Nylander, V.; Spiliotis, I.; van de Bunt, M.; Chibalina, M.; Barrett, A.; Burrows, C.; Tarasov, A.; Scharfmann, R.; Gloyn, A.; Rorsman, P.

10.1101/226282 — cell biology — Posted on 2017-11-29

133 Toward Machine Learning-based Data-driven Functional Protein Studies: Understanding Colour Tuning Rules and Predicting the Absorption Wavelengths of Microbial Rhodopsins

Karasuyama, M.; Inoue, K.; Kandori, H.; Takeuchi, I.

10.1101/226118 — biophysics — Posted on 2017-11-29

134 Biomolecular simulations under realistic macroscopic salt conditions

Ross, G.; Rustenburg, A. S.; Grinaway, P. B.; Fass, J.; Chodera, J. D.

10.1101/226001 — biophysics — Posted on 2017-11-29

135 scmap - A tool for unsupervised projection of single cell RNA-seq data

Kiselev, V. Y.; Yiu, A.; Hemberg, M.

10.1101/150292 — bioinformatics — Posted on 2017-11-29

136 Module analysis captures pancancer (epi)genetically deregulated cancer driver genes for smoking and antiviral response

Champion, M.; Brennan, K.; Croonenborghs, T.; Gentles, A. J.; Pochet, N.; Gevaert, O.

10.1101/216754 — bioinformatics — Posted on 2017-11-29

137 Label-free non-invasive quantitative measurement of lipid contents in individual microalgal cells using refractive index tomography

Jung, J.; Hong, S.-J.; Kim, H.-B.; Kim, G.; Lee, M.; Shin, S.; Lee, S.; Kim, D.-J.; Lee, C.-G.; Park, Y.

10.1101/226480 — bioengineering — Posted on 2017-11-29

138 Presence of WH2 like domain in VgrG-1 toxin of Vibrio cholerae reveals the molecular mechanism of actin cross-linking

Dutta, P.; A S, J.; Mazumder, M.; Dileep, D.; Gourinath, S.; Mukhopadhyay, A. K.; Maiti, S.

10.1101/226605 — biochemistry — Posted on 2017-11-29

139 The MALDI TOF E2/E3 ligase assay as an universal tool for drug discovery in the ubiquitin pathway

De Cesare, V.; Johnson, C.; Barlow, V.; Hastie, J.; Knebel, A.; Trost, M.

10.1101/224600 — biochemistry — Posted on 2017-11-29

140 RESCUE OF AN AGGRESSIVE FEMALE SEXUAL COURTSHIP IN MICE BY CRISPR/Cas9 SECONDARY MUTATION IN VIVO.

Zakany, J.; Duboule, D.

10.1101/226639 — animal behavior and cognition — Posted on 2017-11-29

141 Practice induces a qualitative change in the memory representation for visuomotor learning

Huberdeau, D. M.; Krakauer, J. W.; Haith, A. M.

10.1101/226415 — neuroscience — Posted on 2017-11-28

142 Integrated Analysis of Gene Expression Differences in Twins Discordant for Disease and Binary Phenotypes

Tangirala, S.; Patel, C.

10.1101/226449 — genomics — Posted on 2017-11-28

143 Effect of migration and environmental heterogeneity on the maintenance of quantitative variation: a simulation study

McDonald, T. K.; Yeaman, S.

10.1101/226381 — evolutionary biology — Posted on 2017-11-28

144 A linear-time algorithm to sample the dual-birth model

Moshiri, N.

10.1101/226423 — bioinformatics — Posted on 2017-11-28

145 Biofilm Lithography: High-resolution cell patterning via optogenetic adhesin expression

Jin, X.; Riedel-Kruse, I. H.

10.1101/226027 — synthetic biology — Posted on 2017-11-28

146 Tracking and optimizing human performance using deep reinforcement learning in closed-loop behavioral- and neurofeedback: a proof of concept

Dinov, M.; Leech, R.

10.1101/225995 — neuroscience — Posted on 2017-11-28

147 Thalamocortical Projectional Divergence Leads to Complexity in Functional Organizations in Mouse Auditory Cortex

Ohga, S.; Tsukano, H.; Horie, M.; Terashima, H.; Nishio, N.; Kubota, Y.; Takahashi, K.; Hishida, R.; Takebayashi, H.; Shibuki, K.

10.1101/226100 — neuroscience — Posted on 2017-11-28

148 All-Resolutions Inference for Brain Imaging

Rosenblatt, J. D.; Finos, L.; Weeda, W. D.; Solari, A.; Goeman, J. J.

10.1101/226126 — neuroscience — Posted on 2017-11-28

149 Tracking the dynamic functional connectivity structure of the human brain across the adult lifespan

Xia, Y.; Chen, Q.; Li, M.; Qiu, J.

10.1101/226043 — neuroscience — Posted on 2017-11-28

150 Short-term dosage regimen for stimulation-induced long-lasting desynchronization

Manos, T.; Zeitler, M.; Tass, P.

10.1101/226134 — neuroscience — Posted on 2017-11-28

151 Laminar-specific cortical dynamics in human visual and sensorimotor cortices

Bonaiuto, J. J.; Meyer, S. S.; Little, S.; Rossiter, H.; Callaghan, M. F.; Dick, F.; Barnes, G. R.; Bestmann, S.

10.1101/226274 — neuroscience — Posted on 2017-11-28

152 Disruption to functional networks in neonates with perinatal brain injury predicts motor skills at 8 months

Linke, A. C.; Wild, C.; Zubiaurre-Elorza, L.; Herzmann, C.; Duffy, H.; Han, V. K.; Lee, D. S.; Cusack, R.

10.1101/226340 — neuroscience — Posted on 2017-11-28

153 Knockdown of Liver-Derived C1 Inhibitor Results in Brain Pathology in mice

Farfara, D.; Feierman, E.; Richards, A.; Revenko, A. S.; MacLeod, R. A.; Norris, E. H.; Strickland, S.

10.1101/216531 — neuroscience — Posted on 2017-11-28

154 RodZ promotes MreB polymer formation and curvature localization to determine the cylindrical uniformity of E. coli shape

Morgenstein, R. M.; Bratton, B. P.; Shaevitz, J. W.; Gitai, Z.

10.1101/226290 — microbiology — Posted on 2017-11-28

155 Modelling the effects of bacterial cell state and spatial location on tuberculosis treatment: Insights from a hybrid multiscale cellular automaton model

Bowness, R.; Chaplain, M. A. J.; Powathill, G. G.; Gillespie, S. H.

10.1101/059113 — microbiology — Posted on 2017-11-28

156 Recurrence of de novo mutations in families

Jonsson, H.; Sulem, P.; Arnadottir, G. A.; Palsson, G.; Eggertsson, H. P.; Kristmundsdottir, S.; Zink, F.; Kehr, B.; Hjorleifsson, K. E.; Jensson, B. O.; Jonsdottir, I.; Marelsson, S. E.; Gudjonsson, S. A.; Gylfason, A.; Jonasdottir, A.; Jonasdottir, A.; Stacey, S. N.; Magnusson, O. T.; Thorsteinsdottir, U.; Masson, G.; Kong, A.; Halldorsson, B. V.; Helgason, A.; Gudbjartsson, D. F.; Stefansson, K.

10.1101/221259 — genomics — Posted on 2017-11-28

157 Whole genome and RNA sequencing of 1,220 cancers reveals hundreds of genes deregulated by rearrangement of cis-regulatory elements

Zhang, Y.; Chen, F.; Fonseca, N. A.; He, Y.; Fujita, M.; Nakagawa, H.; Zhang, Z.; Brazma, A.; Creighton, C.

10.1101/099861 — genomics — Posted on 2017-11-28

158 QTLseqr: An R package for bulk segregant analysis with next-generation sequencing

Mansfeld, B. N.; Grumet, R.

10.1101/208140 — genomics — Posted on 2017-11-28

159 Caudal counter-represses Hunchback to regulate even-skipped stripe 2 expression in Drosophila embryos

Vincent, B. J.; Staller, M. V.; Lopez-Rivera, F.; Bragdon, M. D.; Wunderlich, Z.; Estrada, J.; DePace, A. H.

10.1101/226373 — genetics — Posted on 2017-11-28

160 Phylogenomics of montane frogs of the Brazilian Atlantic Forest supports a scenario of isolation in sky islands followed by relative climatic stability

Pie, M. R.; Faircloth, B. C.; Ribeiro, L. F.; Bornschein, M. R.; McCormack, J.

10.1101/226159 — evolutionary biology — Posted on 2017-11-28

161 Developmental loci harbor clusters of accelerated regions that evolved independently in ape lineages

Kostka, D.; Holloway, A. K.; Pollard, K.

10.1101/226019 — evolutionary biology — Posted on 2017-11-28

162 Alternative mating tactics and tactical deception: Is the common cuttlefish (Sepia officinalis) nothing but a common cheat?

Cooke, G. M.

10.1101/226191 — evolutionary biology — Posted on 2017-11-28

163 Population genomic analysis reveals contrasting demographic changes of two closely related dolphin species in the last glacial

Vijay, N.; Park, C.; Oh, J.; Jin, S.; Kern, E.; Kim, H. W.; Zhang, J.; Park, J.-K.

10.1101/225987 — evolutionary biology — Posted on 2017-11-28

164 Diminishing returns of inoculum size on the rate of a plant RNA virus evolution

Navarro, R.; Ambros, S.; Martinez, F.; Elena, S. F.

10.1101/226357 — evolutionary biology — Posted on 2017-11-28

165 Host shifts result in parallel genetic changes when viruses adapt to closely related species

Longdon, B.; Day, J. P.; Alves, J. M.; Smith, S. C.; Houslay, T. M.; McGonigle, J. E.; Tagliaferri, L.; Jiggins, F. M.

10.1101/226175 — evolutionary biology — Posted on 2017-11-28

166 Statistical power of clinical trials has increased whilst effect size remained stable: an empirical analysis of 137 032 clinical trials between 1975-2017

Lamberink, H. J.; Otte, W. M.; Sinke, M. R.; Lakens, D.; Glasziou, P. P.; Tijdink, J. K.; Vinkers, C. H.

10.1101/225730 — epidemiology — Posted on 2017-11-28

167 Transmission patterns of hyper-endemic multi-drug resistant Klebsiella pneumoniae in a Cambodian neonatal unit: a longitudinal study with whole genome sequencing

Smit, P.; Stoesser, N.; Pol, S.; van Kleef, E.; Oonsivilai, M.; Tan, P.; Neou, L.; Turner, C.; Turner, P.; Cooper, B. S.

10.1101/223701 — epidemiology — Posted on 2017-11-28

168 Automated detection of sleep-boundary times using wrist-worn accelerometry

O'Donnell, J.; Hollowell, S.; Salimi-Khorshidi, G.; Velardo, C.; Sexton, C.; Rahimi, K.; Johansen-Berg, H.; Tarassenko, L.; Doherty, A.

10.1101/225516 — epidemiology — Posted on 2017-11-28

169 Causal inference in cancer epidemiology: what is the role of Mendelian randomization?

Yarmolinsky, J.; Wade, K. H.; Richmond, R. C.; Langdon, R. J.; Bull, C. J.; Tilling, K. M.; Relton, C. L.; Lewis, S. J.; Smith, G. D.; Martin, R. M.

10.1101/223966 — epidemiology — Posted on 2017-11-28

170 Metabarcoding for the parallel identification of several hundred predators and their preys: application to bat species diet analysis

Galan, M.; Pons, J.-B.; Tournayre, O.; Pierre, E.; Leuchtmann, M.; Pontier, D.; Charbonnel, N.

10.1101/155721 — ecology — Posted on 2017-11-28

171 Distance Sampling in R

Miller, D. L.; Rexstad, E.; Thomas, L.; Marshall, L.; Laake, J.

10.1101/063891 — ecology — Posted on 2017-11-28

172 Evaluating a sepsis prediction machine learning algorithm using minimal electronic health record data in the emergency department and intensive care unit

Burdick, H.; Pino, E.; Gabel-Comeau, D.; Gu, C.; Huang, H.; Lynn-Palevsky, A.; Das, R.

10.1101/224014 — clinical trials — Posted on 2017-11-28

173 Targeting regulatory T cells with Interleukin-2 treatment in type 1 diabetes: a response-adaptive, non-randomised, open-label trial of repeat doses of Aldesleukin (DILfrequency)

Seelig, E.; Howlett, J.; Porter, L.; Truman, L.; Heywood, J.; Kennet, J.; Arbon, E. L.; Anselmiova, K.; Walker, N. M.; Atkar, R.; Pekaiski, M. L.; Rytina, E.; Evans, M.; Wicker, L. S.; Todd, J. A.; Mander, A. P.; Bond, S.; Waldron-Lynch, F.

10.1101/223958 — clinical trials — Posted on 2017-11-28

174 Uncoupling Intraflagellar Transport and Primary Cilia Formation Demonstrates Deep Integration of IFT in Hedgehog Signaling

Eguether, T. J.; Cordelieres, F. P.; Pazour, G. J.

10.1101/226324 — cell biology — Posted on 2017-11-28

175 Uncoupling Intraflagellar Transport and Primary Cilia Formation Demonstrates Deep Integration of IFT in Hedgehog Signaling

Eguether, T.; Cordelieres, F. P.; Pazour, G. J.

10.1101/226324 — cell biology — Posted on 2017-11-28

176 Tumor-specific Causal Inference (TCI): A Bayesian Method for Identifying Causative Genome Alterations within Individual Tumors

Cooper, G.; Cai, C.; Lu, X.

10.1101/225631 — bioinformatics — Posted on 2017-11-28

177 Photocatalytic disinfection of surfaces with copper doped TiO2 nanotube coatings illuminated by ceiling mounted fluorescent lights

Koklic, T.; Pintaric, S.; Zdovc, I.; Golob, M.; Umek, P.; Mehle, A.; Dobeic, M.; Strancar, J.

10.1101/225615 — bioengineering — Posted on 2017-11-28

178 PWO1 interacts with PcG proteins and histones to regulate Arabidopsis flowering and development.

Hohenstatt, M. L.; Mikulski, P.; Komarynets, O.; Klose, C.; Kycia, I.; Jeltsch, A.; Farrona, S.; Schubert, D.

10.1101/226183 — plant biology — Posted on 2017-11-28

179 The Functional Connectivity between the Locust Leg Pattern Generating Networks and the Subesophageal Ganglion Higher Motor Center

Knebel, D.; Rillich, J.; Nadler, L.; Pflueger, H. J.; Ayali, A.

10.1101/226167 — neuroscience — Posted on 2017-11-28

180 Sparse Bursts Optimize Information Transmission

Naud, R.; Sprekeler, H.

10.1101/143636 — neuroscience — Posted on 2017-11-28

181 Network supporting contextual fear learning after dorsal hippocampal damage has increased dependence on retrosplenial cortex

Coelho, C. A. O.; Ferreira, T. L.; Soares, J. C. K.; Sato, J. R.; Oliveira, M. G. M.

10.1101/209866 — neuroscience — Posted on 2017-11-28

182 Temporal transitions of spontaneous brain activity

Ma, Z.; Zhang, N.

10.1101/166512 — neuroscience — Posted on 2017-11-28

183 PWWP INTERACTOR OF POLYCOMBS (PWO1) links PcG-mediated gene repression to the nuclear lamina in Arabidopsis.

Mikulski, P.; Hohenstatt, M. L.; Farrona, S.; Smaczniak, C.; Kaufmann, K.; Angenent, G.; Schubert, D.

10.1101/220541 — molecular biology — Posted on 2017-11-28

184 CTCF mediated genome architecture regulates the dosage of mitotically stable mono-allelic expression of autosomal genes

Chandradoss, K. R.; Sandhu, K. S.

10.1101/178749 — genomics — Posted on 2017-11-28

185 Co-regulation of transcription by BRG1 and BRM, two mutually exclusive SWI/SNF ATPase subunits

Raab, J.; Runge, J. S.; Spear, C. C.; Magnuson, T.

10.1101/178848 — genomics — Posted on 2017-11-28

186 Pathogen evolution: slow and steady spreads the best

Parsons, T.; Lambert, A.; Day, T.; Gandon, S.

10.1101/225599 — evolutionary biology — Posted on 2017-11-28

187 A Theory For Ecological Survey Methods To Map Individual Distributions

Takashina, N.; Beger, M.; Kusumoto, B.; Rathnayake, S.; Possingham, H.

10.1101/137158 — ecology — Posted on 2017-11-28

188 Evolution and cell-type specificity of human-specific genes preferentially expressed in progenitors of fetal neocortex

Florio, M.; Heide, M.; Brandl, H.; Pinson, A.; Winkler, S.; Wimberger, P.; Huttner, W. B.; Hiller, M.

10.1101/225722 — developmental biology — Posted on 2017-11-28

189 PDGFRα signaling in cardiac stem and stromal cells modulates quiescence, metabolism and self-renewal, and promotes anatomical and functional repair

Harvey, R. P.; Asili, N.; Xaymardan, M.; Forte, E.; Waardenberg, A. J.; Cornwell, J.; Janbandhu, V.; Kesteven, S.; Chandrakanthan, V.; Malinowska, H.; Reinhard, H.; Yang, S.; Pickett, H.; Schofield, P.; Christ, D.; Ahmed, I.; Chong, J.; Heffernan, C.; Li, J.; Simonian, M.; Bouveret, R.; Srivastava, S.; Mishra, R.; Dhawan, J.; Nordon, R.; Macdonald, P.; Graham, R.; Feneley, M.

10.1101/225979 — cell biology — Posted on 2017-11-28

190 Understanding boundary effects and confocal optics enables quantitative FRAP analysis in the confined geometries of animal, plant, and fungal cells

Kingsley, J. L.; Bibeau, J. P.; Mousavi, I.; Unsal, C.; Chen, Z.; Huang, X.; Vidali, L.; Tuzel, E.

10.1101/059220 — biophysics — Posted on 2017-11-28

191 What goes up must come down - Biomechanical impact analysis of jumping locusts

Reichel, S.; Labisch, S.; Dirks, J.-H.

10.1101/225672 — zoology — Posted on 2017-11-27

192 Prioritized memory access explains planning and hippocampal replay

Mattar, M. G.; Daw, N. D.

10.1101/225664 — neuroscience — Posted on 2017-11-27

193 Energy saving in vision at the first synapse: The ON and OFF pathways measure temporal differences

ter Haar Romeny, B. M.

10.1101/225557 — neuroscience — Posted on 2017-11-27

194 Dopaminergic drug treatment remediates exaggerated cingulate prediction error responses in obsessive-compulsive disorder

Murray, G. K.; Knolle, F.; Ersche, K. D.; Craig, K. J.; Abbot, S.; Shabbir, S. S.; Fineberg, N. A.; Suckling, J.; Sahakian, B. J.; Bullmore, E. T.; Robbins, T. W.

10.1101/225938 — neuroscience — Posted on 2017-11-27

195 Reversed depth in anti-correlated random dot stereograms and central-peripheral difference in visual inference

Zhaoping, L.; Ackermann, J.

10.1101/225532 — neuroscience — Posted on 2017-11-27

196 Learning to read the imprints of consciousness on global brain dynamics: an application to intra-operative monitoring of anesthesia

Alonso, L. M.; Solovey, G.; Yanagawa, T.; Proekt, A.; Cecchi, G.; Magnasco, M. O.

10.1101/225813 — neuroscience — Posted on 2017-11-27

197 The effects of host species and sexual dimorphism differ among root, leaf and flower microbiomes of wild strawberries in situ

Wei, N.; Ashman, T.-L.

10.1101/225755 — microbiology — Posted on 2017-11-27

198 Drug repurposing for yellow fever using high content screening

Pilger, D. R.; Borsoi Moraes, C.; Gil, L.; Freitas-Junior, L.

10.1101/225656 — microbiology — Posted on 2017-11-27

199 Endospores and other lysis-resistant bacteria comprise a widely shared core community within the human microbiota

Kearney, S. M.; Gibbons, S. M.; Poyet, M.; Gurry, T.; Bullock, K.; Allegretti, J.; Clish, C.; Alm, E. J.

10.1101/221713 — microbiology — Posted on 2017-11-27

200 Deferiprone, an iron chelator, is preventive and therapeutic in experimental crescentic glomerulonephritis

Chen, T.-D.; Ko, J.-H.; Prendecki, M.; McAdoo, S. P.; Pusey, C. D.; Cook, H. T.; Behmoaras, J.

10.1101/225540 — immunology — Posted on 2017-11-27

201 Systems genetics identifies modifiers of Alzheimer’s disease risk and resilience

Neuner, S. M.; Hohman, T. J.; Richholt, R.; Bennett, D. A.; Schneider, J. A.; De Jager, P. L.; Huentelman, M. J.; O'Connell, K. M. S.; Kaczorowski, C. C.

10.1101/225714 — genetics — Posted on 2017-11-27

202 Early Archean origin of heterodimeric Photosystem I

Cardona, T.

10.1101/225888 — evolutionary biology — Posted on 2017-11-27

203 The Plateau Method for Forensic DNA SNP Mixture Deconvolution

Ricke, D. O.; Isaacson, J.; Watkins, J.; Fremont-Smith, P.; Boettcher, T.; Petrovick, M.; Wack, E.; Schwoebel, E.

10.1101/225805 — bioinformatics — Posted on 2017-11-27

204 Paramecium Learning: New Insights and Modifications

Alipour, A.; Dorvash, M.; Yeganeh, Y.; Hatam, G.

10.1101/225250 — animal behavior and cognition — Posted on 2017-11-27

205 Invasion and migration of spatially self-limiting gene drives: a comparative analysis

Dhole, S.; Vella, M. R.; Lloyd, A. L.; Gould, F.

10.1101/159855 — synthetic biology — Posted on 2017-11-27

206 Eukaryotically expressed encapsulins as orthogonal compartments for multiscale molecular imaging

Sigmund, F.; Massner, C.; Erdmann, P.; Stelzl, A.; Rolbieski, H.; Fuchs, H.; Hrabe de Angelis, M.; Desai, M.; Bricault, S.; Jasanoff, A.; Ntziachristos, V.; Plitzko, J.; Westmeyer, G. G.

10.1101/222083 — synthetic biology — Posted on 2017-11-27

207 A design framework and exemplar metrics for FAIRness

Wilkinson, M. D.; Sansone, S.-A.; Schultes, E.; Doorn, P.; Bonino da Silva Santos, L. O.; Dumontier, M.

10.1101/225490 — scientific communication and education — Posted on 2017-11-27

208 Diabetic Retinopathy detection through integration of Deep Learning classification framework

Rakhlin, A.

10.1101/225508 — pathology — Posted on 2017-11-27

209 Behavioral and neural indices of affective coloring for neutral social stimuli

Grupe, D. W.; Schaefer, S. M.; Lapate, R. C.; Schoen, A. J.; Gresham, L. K.; Mumford, J. A.; Davidson, R. J.

10.1101/178384 — neuroscience — Posted on 2017-11-27

210 Estimating the number of missing experiments in a neuroimaging meta-analysis

Samartsidis, P.; Montagna, S.; Laird, A. R.; Fox, P. T.; Johnson, T. D.; Nichols, T. E.

10.1101/225425 — neuroscience — Posted on 2017-11-27

211 Functional Parcellation of the Default Mode Network: A Large-Scale Meta-Analysis

Wang, S.; Taren, A. A.; Smith, D. V.

10.1101/225375 — neuroscience — Posted on 2017-11-27

212 Knockdown of Liver-Derived C1 Inhibitor Results in Brain Pathology in mice

Farfara, D.; Feierman, E.; Richards, A.; Revenko, A. S.; MacLeod, R. A.; Norris, E. H.; Strickland, S.

10.1101/216531 — neuroscience — Posted on 2017-11-27

213 Determinants of target prioritization and regulatory hierarchy for the bacterial small RNA SgrS

Bobrovskyy, M.; Frandsen, J. K.; Zhang, J.; Poddar, A.; Azam, M. S.; Henkin, T. M.; Ha, T.; Vanderpool, C. K.

10.1101/221978 — microbiology — Posted on 2017-11-27

214 Origin, evolution, and distribution of the molecular machinery for biosynthesis of sialylated lipooligosaccharide structures in Campylobacter coli

Culebro, A.; Machado, M. P.; Carrico, J. A.; Rossi, M.

10.1101/225771 — microbiology — Posted on 2017-11-27

215 Dissecting FcγR Regulation Through a Multivalent Binding Model

Robinett, R. A.; Guan, N.; Lux, A.; Biburger, M.; Nimmerjahn, F.; Meyer, A. S.

10.1101/142273 — immunology — Posted on 2017-11-27

216 Integrating animal movement with habitat suitability for estimating dynamic landscape connectivity

van Toor, M. L.; Kranstauber, B.; Newman, S. H.; Prosser, D. J.; Takekawa, J. Y.; Technitis, G.; Weibel, R.; Wikelski, M.; Safi, K.

10.1101/224766 — ecology — Posted on 2017-11-27

217 Frequency-dependent Maternal Effects across Species and Environments

Germain, R. M.; Grainger, T. N.; Jones, N. T.; Gilbert, B.

10.1101/225763 — ecology — Posted on 2017-11-27

218 Predator-prey feedback in a gyrfalcon-ptarmigan system?

Barraquand, F.; Nielsen, O. K.

10.1101/220038 — ecology — Posted on 2017-11-27

219 A damped oscillator imposes temporal order on posterior gap gene expression in Drosophila

Verd, B.; Clark, E.; Wotton, K. R.; Janssens, H.; Jimenez-Guri, E.; Crombach, A.; Jaeger, J.

10.1101/068072 — developmental biology — Posted on 2017-11-27

220 Androgen receptor binding sites are highly mutated in prostate cancer

MOROVA, T.; GÖNEN, M.; GÜRSOY, A.; KESKIN, O.; LACK, N. A.

10.1101/225433 — cancer biology — Posted on 2017-11-27

221 Gaussian Curvature Directs The Distribution Of Spontaneous Curvature On Bilayer Membrane Necks

Chabanon, M.; Rangamani, P.

10.1101/137091 — biophysics — Posted on 2017-11-27

222 Mining therapeutic insights from large scale drug screenings with transfer learning

Yang, M.; Simm, J.; Zakeri, P.; Moreau, Y.; Saez-Rodriguez, J.

10.1101/225573 — bioinformatics — Posted on 2017-11-27

223 Bioentities: a resource for entity recognition and relationship resolution in biomedical text mining

Bachman, J. A.; Gyori, B. M.; Sorger, P.

10.1101/225698 — bioinformatics — Posted on 2017-11-27

224 Producing Hfq/Sm Proteins and sRNAs for Structural and Biophysical Studies of Ribonucleoprotein Assembly

Stanek, K. A.; Mura, C.

10.1101/150672 — biochemistry — Posted on 2017-11-27

225 Producing Hfq/Sm Proteins and sRNAs for Structural and Biophysical Studies of Ribonucleoprotein Assembly

Stanek, K. A.; Mura, C.

10.1101/150672 — biochemistry — Posted on 2017-11-27

226 EASI-tag enables accurate multiplexed and interference-free MS2-based proteome quantification

Virreira Winter, S.; Meier, F.; Wichmann, C.; Cox, J.; Mann, M.; Meissner, F.

10.1101/225649 — biochemistry — Posted on 2017-11-27

227 The structure of SALM5 suggests a dimeric assembly for the presynaptic RPTP ligand recognition

Karki, S.; Paudel, P.; Sele, C.; Shkumatov, A. V.; Kajander, T.

10.1101/225821 — biochemistry — Posted on 2017-11-27

228 Equine strongyle communities are constrained by horse sex and species dipersal-fecundity trade-off

Salle, G.; Kornas, S.; Basiaga, M.

10.1101/225417 — zoology — Posted on 2017-11-27

229 Proteomics of phosphorylation and protein dynamics during fertilization and meiotic exit in the Xenopus egg

Presler, M. S.; Van Itallie, E.; Klein, A. M.; Kunz, R.; Coughlin, P.; Peshkin, L.; Gygi, S.; Wühr, M.; Kirschner, M.

10.1101/145086 — systems biology — Posted on 2017-11-27

230 Mapping the phenotypic repertoire of the cytoplasmic 2-Cys peroxiredoxin - thioredoxin system. 1. Understanding commonalities and differences among cell types.

Selvaggio, G.; Coelho, P. M. B. M.; Salvador, A.

10.1101/224428 — systems biology — Posted on 2017-11-27

231 Modeling Dynamic Transcriptional Circuits with CRISPRi

Clamons, S. E.; Murray, R. M.

10.1101/225318 — synthetic biology — Posted on 2017-11-27

232 Statistical testing and power analysis for brain-wide association study

Gong, W.; Wan, L.; Lu, W.; Ma, L.; Cheng, F.; Cheng, W.; Gruenewald, S.; Feng, J.

10.1101/089870 — neuroscience — Posted on 2017-11-27

233 Automated 3D Neuron Tracing with Precise Branch Erasing and Confidence Controlled Back-Tracking

Liu, S.; Zhang, D.; Song, Y.; Peng, H.; Cai, W.

10.1101/109892 — neuroscience — Posted on 2017-11-27

234 Altered neurocognitive processing of tactile stimuli in patients with Complex Regional Pain Syndrome (CRPS)

Kuttikat, A.; Noreika, V.; Chennu, S.; Shenker, N.; Bekinschtein, T.; Brown, C.

10.1101/146613 — neuroscience — Posted on 2017-11-27

235 Convis: A Toolbox To Fit and Simulate Filter-based Models of Early Visual Processing

Huth, J.; Masquelier, T.; Arleo, A.

10.1101/169284 — neuroscience — Posted on 2017-11-27

236 Molecule guided laser ablation as a novel therapeutic strategy to control itch.

Nocchi, L.; D'Attilia, M.; Roy, N.; Dhandapani, R.; Traista, A.; Maffei, M.; Castaldi, L.; Perlas, E.; Heppenstall, P. A.

10.1101/225391 — neuroscience — Posted on 2017-11-27

237 Instructive starPEG-Heparin biohybrid 3D cultures for modeling human neural stem cell plasticity, neurogenesis, and neurodegeneration

Papadimitriou, C.; Cosacak, M. I.; Mashkaryan, V.; Celikkaya, H.; Bray, L.; Bhattarai, P.; Hollak, H.; Chen, X.; He, S.; Antos, C. L.; Thomas, A.; Friedrichs, J.; Dahl, A.; Zhang, Y.; Freudenberg, U.; Werner, C.; Kizil, C.

10.1101/225243 — neuroscience — Posted on 2017-11-27

238 Shared Spatiotemporal Category Representations in Biological and Artificial Deep Neural Networks

Greene, M. R.; Hansen, B. C.

10.1101/225607 — neuroscience — Posted on 2017-11-27

239 GABAergic deficits and schizophrenia-like behaviors in a mouse model carrying patient-derived neuroligin-2 R215H mutation

Chen, G.; Jiang, D.; Wu, Z.; Hu, Y.; Yee, S.-P.

10.1101/225524 — neuroscience — Posted on 2017-11-27

240 Extended "Constant Field" equations: an electrodiffusion model of NMDA receptors

Moradi, K.; Moradi, K.; Bakouie, F.; Gharibzadeh, S.

10.1101/221408 — neuroscience — Posted on 2017-11-27

241 Anterior cingulate cortex connectivity is associated with suppression of behavior in a rat model of chronic pain

Morris, L. S.; Sprenger, C.; Koda, K.; de la Mora, D. M.; Yamada, T.; Mano, H.; Kashiwagi, Y.; Yoshioka, Y.; Morioka, Y.; Seymour, B.

10.1101/225482 — neuroscience — Posted on 2017-11-27

242 Potential high-frequency off-target mutagenesis induced by CRISPR/Cas9 in Arabidopsis and its prevention

Zhang, Q.; Xing, H.-L.; Wang, Z.-P.; Zhang, H.-Y.; Yang, F.; Wang, X.-C.; Chen, Q.-J.

10.1101/203489 — molecular biology — Posted on 2017-11-27

243 A single cycle influenza virus coated in H7 hemagglutinin provides heterotypic protection and neutralising antibody responses to both glycoproteins.

Powell, T. J.; Rijal, P.; McEwen-Smith, R. M.; Byun, H.; Hardwick, M.; Schimanski, L. M.; Huang, K.-Y. A.; Daniels, R. S.; Townsend, A. R. M.

10.1101/224550 — immunology — Posted on 2017-11-27

244 Comparison of reprogramming factor targets reveals both species-specific and conserved mechanisms in early iPS cells

Fu, K.; Chronis, C.; Soufi, A.; Bonora, G.; Edwards, M.; Smale, S.; Zaret, K.; Plath, K.; Pellegrini, M.

10.1101/225326 — genomics — Posted on 2017-11-27

245 A tutorial on how (not) to over-interpret STRUCTURE/ADMIXTURE bar plots

Lawson, D.; van Dorp, L.; Falush, D.

10.1101/066431 — genetics — Posted on 2017-11-27

246 Integrated genomics and protein interaction analyses implicate postsynaptic signaling in schizophrenia

Schijven, D.; Kofink, D.; Tragante, V.; Verkerke, M.; Pulit, S. L.; Kahn, R. S.; Veldink, J. H.; Vinkers, C. H.; Boks, M. P.; Luykx, J. J.

10.1101/117481 — genetics — Posted on 2017-11-27

247 Common risk variants identified in autism spectrum disorder

Grove, J.; Ripke, S.; Als, T. D.; Mattheisen, M.; Walters, R.; Won, H.; Pallesen, J.; Agerbo, E.; Andreassen, O. A.; Anney, R.; Belliveau, R.; Bettella, F.; Buxbaum, J. D.; Bybjerg-Grauholm, J.; Baekved-Hansen, M.; Cerrato, F.; Chambert, K.; Christensen, J. H.; Churchhouse, C.; Dellenvall, K.; Demontis, D.; De Rubeis, S.; Devlin, B.; Djurovic, S.; Dumont, A.; Goldstein, J.; Hansen, C. S.; Hauberg, M. E.; Hollegaard, M. V.; Hope, S.; Howrigan, D. P.; Huang, H.; Hultman, C.; Klei, L.; Maller, J.; Martin, J.; Martin, A. R.; Moran, J.; Nyegaard, M.; Naerland, T.; Palmer, D. S.; Palotie, A.; Peders

10.1101/224774 — genetics — Posted on 2017-11-27

248 Genomic relationships reveal significant dominance effects for growth in hybrid Eucalyptus

Tan, B.; Grattapaglia, D.; Wu, H. X.; Ingvarsson, P. K.

10.1101/178160 — genetics — Posted on 2017-11-27

249 A data-driven model for the assessment of Tuberculosis transmission in evolving demographic structures.

Arregui, S.; Marinova, D.; Iglesias, M. J.; Samper, S.; Martin, C.; Sanz, J.; Moreno, Y.

10.1101/112409 — epidemiology — Posted on 2017-11-27

250 Failure through expanding voids in bacterial streamers

Biswas, I.; Ghosh, R.; Sadrzadeh, M.; Kumar, A.

10.1101/225367 — biophysics — Posted on 2017-11-27

251 Architecture of human interphase chromosome determines the spatiotemporal dynamics of chromatin loci

Liu, L.; Shi, G.; Thirumalai, D.; Hyeon, C.

10.1101/223669 — biophysics — Posted on 2017-11-27

252 High-throughput ANI Analysis of 90K Prokaryotic Genomes Reveals Clear Species Boundaries

Jain, C.; Rodriguez-R, L. M.; Phillippy, A. M.; Konstantinidis, K. T.; Aluru, S.

10.1101/225342 — bioinformatics — Posted on 2017-11-27

253 RecoverY: K-mer based read classification for Y-chromosome specific sequencing and assembly

Rangavittal, S.; Harris, R. S.; Cechova, M.; Tomaszkiewicz, M.; Chikhi, R.; Makova, K.; Medvedev, P.

10.1101/148114 — bioinformatics — Posted on 2017-11-27

254 Reconstructing phylogeny from reduced-representation genome sequencing data without assembly or alignment

Fan, H.; Ives, A. R.; Surget-Groba, Y.

10.1101/225623 — bioinformatics — Posted on 2017-11-27

255 ProLego: tool for extracting and visualizing topological modules in protein structures

Khan, T.; Panday, S. K.; Ghosh, I.

10.1101/225565 — bioinformatics — Posted on 2017-11-27

256 Dimerization of the Pragmin pseudo-kinase regulates protein tyrosine phosphorylation

lecointre, c.; simon, v.; kerneur, c.; allemand, f.; fournet, a.; montarras, i.; pons, j.-l.; gelin, m.; brignatz, c.; urbach, s.; labesse, g.; roche, s.

10.1101/218669 — biochemistry — Posted on 2017-11-27

257 Refactoring gene sequences for broad assembly standards compatibility

Shepherd, T. R.

10.1101/225284 — synthetic biology — Posted on 2017-11-26

258 AtRsgA from Arabidopsis thaliana controls maturation of the small subunit of the chloroplast ribosome

Mutwil, M.; Marcin, J.; Zoschke, R.; Scharff, L.; Jaime, S. M.; Ferrari, C.; Proost, S.; Omranian, N.; Musialak-Lange, M.; Nikoloski, Z.; Graf, A.; Schottler, M. A.; Sampathkumar, A.; Vaid, N.

10.1101/225052 — molecular biology — Posted on 2017-11-26

259 Redox-Dependent Condensation Of the Mycobacterial Nucleoid By WhiB4

Chawla, M.; Mehta, M.; Parikh, P.; Mishra, S.; Shukla, P.; Vij, M.; Jakkala, K.; Singh, P.; AjitKumar, P.; Verma, H. N.; Ganguli, M.; Seshasayee, A. S. N.; Singh, A.

10.1101/133181 — microbiology — Posted on 2017-11-26

260 DUSP1 regulates apoptosis and cell migration, but not the JIP1-protected cytokine response, during Respiratory Syncytial Virus and Sendai Virus infection

Robitaille, A. C.; Caron, E.; Zucchini, N.; Mukawera, E.; Adam, D.; Mariani, M. K.; Gelinas, A.; Fortin, A.; Brochiero, E.; Grandvaux, N.

10.1101/163360 — microbiology — Posted on 2017-11-26

261 Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

Zekavat, S. M.; Ruotsalainen, S.; Handsaker, R. E.; Alver, M.; Bloom, J.; Poterba, T.; Seed, C.; Ernst, J.; Chaffin, M.; Engreitz, J.; Correa, A.; Metspalu, A.; Salomaa, V.; Kellis, M.; Daly, M. J.; Wilson, J. G.; Neale, B. M.; McCaroll, S.; Surakka, I.; Esko, T.; Ganna, A.; Ripatti, S.; Kathiresan, S.; Natarajan, P.; NHLBI TOPMed Lipids Working Group,

10.1101/225169 — genomics — Posted on 2017-11-26

262 Gene expression response to sea lice in Atlantic salmon skin: an RNA-Seq comparison between resistant and susceptible animals

Robledo, D.; Gutierrez, A. P.; Barria, A.; Yanez, J. M.; Houston, R. D.

10.1101/225094 — genetics — Posted on 2017-11-26

263 Elevated polygenic burden for autism is associated with differential DNA methylation at birth.

Hannon, E.; Schendel, D.; Ladd-Acosta, C.; Grove, J.; iPSYCH-Broad ASD Group, ; Hansen, C. S.; Andrews, S. V.; Hougaard, D.; Bresnahan, M.; Mors, O.; Hollegaard, M. V.; Baekvad-Hansen, M.; Hornig, M.; Mortensen, P. B.; Borglum, A.; Werge, T.; Pedersen, M. G.; Nordentoft, M.; Buxbaum, J.; Fallin, D.; Bybjerg-Grauholm, J.; Reichenberg, A.; Mill, J.

10.1101/225193 — genetics — Posted on 2017-11-26

264 Genomic and geographic footprints of differential introgression between two highly divergent fish species

Souissi, A.; Bonhomme, F.; Manchado, M.; Sfar, L. B.; Gagnaire, P.- A.

10.1101/225201 — evolutionary biology — Posted on 2017-11-26

265 Cytokine response of acute myeloid leukemia cells has impact on patient prognosis: Insights from mathematical modeling

Stiehl, T.; Ho, A. D.; Marciniak-Czochra, A.

10.1101/225235 — cancer biology — Posted on 2017-11-26

266 Neural Interactome: Interactive Simulation of a Neuronal System

Kim, J.; Leahy, W.; Shlizerman, E.

10.1101/209155 — neuroscience — Posted on 2017-11-26

267 Tracing cellular heterogeneity in pooled genetic screens via multi-level barcoding

Boettcher, M.; Covarrubias, S.; Biton, A.; Blau, J. A.; Wang, H.; Zaitlen, N.; McManus, M. T.

10.1101/224345 — genomics — Posted on 2017-11-26

268 DECENT: Differential Expression with Capture Efficiency AdjustmeNT for Single-Cell RNA-seq Data

Ye, C.; Speed, T. P.; Salim, A.

10.1101/225177 — genomics — Posted on 2017-11-26

269 AtRsgA from Arabidopsis thaliana controls maturation of the small subunit of the chloroplast ribosome

Mutwil, M.; Marcin, J.; Zoschke, R.; Scharff, L.; Jaime, S. M.; Ferrari, C.; Proost, S.; Omranian, N.; Musialak-Lange, M.; Nikoloski, Z.; Graf, A.; Schottler, M. A.; Sampathkumar, A.; Vaid, N.

10.1101/225052 — molecular biology — Posted on 2017-11-25

270 Proof of concept continuous event logging in living cells

Shur, A.; Murray, R. M.

10.1101/225151 — synthetic biology — Posted on 2017-11-25

271 Cell-free prototyping strategies for enhancing the sustainable production of polyhydroxyalkanoates bioplastics

Kelwick, R.; Ricci, L.; Chee, S. M.; Bell, D.; Webb, A. J.; Freemont, P. S.

10.1101/225144 — synthetic biology — Posted on 2017-11-25

272 Posterior parietal cortex represents sensory stimulus history and is necessary for its effects on behavior

Akrami, A.; Kopec, C. D.; Diamond, M. E.; Brody, C. D.

10.1101/182246 — neuroscience — Posted on 2017-11-25

273 Brain Modularity Mediates the Relation of Cognitive Performance to Task Complexity

Yue, Q.; Martin, R.; Fischer-Baum, S.; Ramos-Nunez, A. I.; Ye, F.; Deem, M. W.

10.1101/224949 — neuroscience — Posted on 2017-11-25

274 Human VMPFC encodes early signatures of confidence in perceptual decisions

Gherman, S.; Philiastides, M. G.

10.1101/224337 — neuroscience — Posted on 2017-11-25

275 A suite of transgenic driver and reporter mouse lines with enhanced brain cell type targeting and functionality

Daigle, T. L.; Madisen, L.; Hage, T. A.; Valley, M. T.; Knoblich, U.; Larsen, R. S.; Takeno, M. M.; Huang, L.; Gu, H.; Larsen, R.; Mills, M.; Bosma-Moody, A.; Siverts, L.; Walker, M.; Graybuck, L. T.; Yao, Z.; Fong, O.; Garren, E.; Lenz, G.; Chavarha, M.; Pendergraft, J.; Harrington, J.; Hirokawa, K. E.; Harris, J. A.; McGraw, M.; Ollerenshaw, D. R.; Smith, K.; Baker, B. A.; Ting, J. T.; Sunkin, S. M.; Lecoq, J.; Lin, M. Z.; Boyden, E. S.; Murphy, G. J.; da Costa, N.; Waters, J.; Li, L.; Tasic, B.; Zeng, H.

10.1101/224881 — neuroscience — Posted on 2017-11-25

276 Scale-specific analysis of fMRI data on the irregular cortical surface

Chen, Y.; Cichy, R. M.; Stannat, W.; Haynes, J.-D.

10.1101/224873 — neuroscience — Posted on 2017-11-25

277 Stochastic processes dominate the within and between host evolution of influenza virus

McCrone, J. T.; Woods, R. J.; Martin, E. T.; Malosh, R. E.; Monto, A. S.; Lauring, A. S.

10.1101/176362 — microbiology — Posted on 2017-11-25

278 DDX3 is exploited by Arenaviruses to suppress type I interferons and favor their replication

Loureiro, M. E.; Zorzetto-Fernandes, A. L.; Radoshitzky, S.; Chi, X.; Dallari, S.; Marooki, N.; Leger, P.; Foscaldi, S.; Sharma, S.; Lopez, N.; de la Torre, J. C.; Bavari, S.; Zuniga, E.

10.1101/224725 — microbiology — Posted on 2017-11-25

279 Antigen-induced but not innate memory CD8 T cells express NKG2D and are recruited to the lung parenchyma upon viral infection

Grau, M.; Valsesia, S.; Mafille, J.; Djebali, S.; Tomkowiak, M.; Mathieu, A.-L.; Laubreton, D.; De bernard, S.; Jouve, P.-E.; Buffat, L.; Walzer, T.; LEVERRIER, Y.; marvel, j.

10.1101/224782 — immunology — Posted on 2017-11-25

280 Zika virus infection preferentially counterbalances human peripheral monocyte and/or NK-cell activity

Lum, F. M.; Lee, D.; Chua, T.-K.; Tan, J. J.; Lee, C. Y.; Liu, X.; Fang, Y.; Lee, B.; Yee, W.-X.; Rickett, N.; Chia, P.-Y.; Lim, V.; Leo, Y.-S.; Matthews, D.; Hiscox, J.; Ng, L. F.

10.1101/225102 — immunology — Posted on 2017-11-25

281 Expressed Exome Capture Sequencing (EecSeq): a method for cost-effective exome sequencing for all organisms with or without genomic resources

Puritz, J. B.; Lotterhos, K. E.

10.1101/223735 — genomics — Posted on 2017-11-25

282 Deciphering cis-regulatory logic with 100 million synthetic promoters

de Boer, C.; Sadeh, R.; Friedman, N.; Regev, A.

10.1101/224907 — genomics — Posted on 2017-11-25

283 Common risk variants identified in autism spectrum disorder

10.1101/224774 — genetics — Posted on 2017-11-25

284 A non-genetic meiotic repair program inferred from spore survival values in fission yeast wild isolates: a clue for an epigenetic ratchet-like model of ageing?

Marsellach, X.

10.1101/223685 — genetics — Posted on 2017-11-25

285 Gene expression response to sea lice in Atlantic salmon skin: an RNA-Seq comparison between resistant and susceptible animals

Robledo, D.; Gutierrez, A. P.; Barria, A.; Yanez, J.; Houston, R. M.

10.1101/225094 — genetics — Posted on 2017-11-25

286 Common lizards break Dollo’s law of irreversibility: genome-wide phylogenomics support a single origin of viviparity and re-evolution of oviparity

Recknagel, H.; Kamenos, N.; Elmer, K. R.

10.1101/225086 — evolutionary biology — Posted on 2017-11-25

287 A Non-Classical Phase Diagram for Virus-Bacterial Co-Evolution Mediated by CRISPR

Han, P.; Deem, M. W.

10.1101/224923 — evolutionary biology — Posted on 2017-11-25

288 Ecological Change Points: The strength of density dependence and the loss of history

Ponciano, J. M.; Taper, M. L.; Dennis, B.

10.1101/224352 — ecology — Posted on 2017-11-25

289 Re-arrangements in the cytoplasmic distribution of small RNAs following the maternal-to-zygotic transition in Drosophila embryos

Cosacak, M. I.; Yigit, H.; Akgul, B.

10.1101/224626 — developmental biology — Posted on 2017-11-25

290 Dose response relationships for gamma radiation induced chromosomal instability

Eidelman, Y.; Slanina, S.; Pyatenko, V.; Khvostunov, I.; Andreev, S.

10.1101/224741 — cancer biology — Posted on 2017-11-25

291 Nonequilibrium entropic bounds for Darwinian replicators

Pinero, J.; Sole, R.

10.1101/225011 — biophysics — Posted on 2017-11-25

292 scImpute: Accurate And Robust Imputation For Single Cell RNA-Seq Data

Li, W. V.; Li, J. J.

10.1101/141598 — bioinformatics — Posted on 2017-11-25

293 VarExp: Estimating variance explained by Genome-Wide GxE summary statistics

Laville, V.; Bentley, A. R.; Prive, F.; Zhu, X.; Gauderman, W.; Winkler, T.; Province, M.; Rao, D.; Aschard, H.; CHARGE Gene-Lifestyle Interactions Working Group,

10.1101/224634 — bioinformatics — Posted on 2017-11-25

294 AptaBlocks: Accelerating the Design of RNA-based Drug Delivery Systems

Wang, Y.; Hoinka, J.; Swiderski, P.; Przytycka, T. M.

10.1101/216465 — bioinformatics — Posted on 2017-11-25

295 Combining accurate tumour genome simulation with crowd sourcing to benchmark somatic structural variant detection

Lee, A. Y.-W.; Ewing, A. D.; Ellrott, K.; Hu, Y.; Houlahan, K. E.; Bare, J. C.; Espiritu, S. M. G.; Huang, V.; Dang, K.; Chong, Z.; Caloian, C.; Yamaguchi, T. N.; ICGC-TCGA DREAM Somatic Mutation Calling Challenge, ; Kellen, M. R.; Chen, K.; Norman, T. C.; Friend, S. H.; Guinney, J.; Stolovitzky, G.; Haussler, D.; Margolin, A. A.; Stuart, J. M.; Boutros, P. C.

10.1101/224733 — bioinformatics — Posted on 2017-11-25

296 Improving bioinformatics prediction of microRNA targets by ranks aggregation

Quillet, A.; Saad, C.; Ferry, G.; Anouar, Y.; Vergne, N.; Lecroq, T.; Dubessy, C.

10.1101/224915 — bioinformatics — Posted on 2017-11-25

297 Clusterdv, a simple density-based clustering method that is robust, general and automatic.

Marques, J. C.; Orger, M. B.

10.1101/224840 — bioinformatics — Posted on 2017-11-25

298 MICCS: A Fully Programmable Multipurpose Integrated Cell Culture System

Kassis, T.; Perez, P. M.; Yang, C. J. W.; Soenksen, L. R.; Trumper, D. L.; Griffith, L. G.

10.1101/192047 — bioengineering — Posted on 2017-11-25

299 Control of bacterial population density with population feedback and molecular sequestration

McCardell, R. D.; Huang, S.; Green, L. N.; Murray, R. M.

10.1101/225045 — synthetic biology — Posted on 2017-11-25

300 A global comparison of the nutritive values of forage plants grown in contrasting environments

Lee, M.

10.1101/224808 — plant biology — Posted on 2017-11-25

301 Static and dynamic measures of human brain connectivity predict complementary aspects of human cognitive performance

Ramos-Nunez, A. I.; Fischer-Baum, S.; Martin, R.; Yue, Q.; Ye, F.; Deem, M.

10.1101/224956 — neuroscience — Posted on 2017-11-25

302 Binding of the integrated stress response inhibitor, ISRIB, reveals a regulatory site in the nucleotide exchange factor, eIF2B

Zyryanova, A. F.; Weis, F.; Faille, A.; Abo Alard, A.; Crespillo-Casado, A.; Harding, H. P.; Allen, F.; Parts, L.; Fromont, C.; Fischer, P. M.; Warren, A. J.; Ron, D.

10.1101/224824 — molecular biology — Posted on 2017-11-25

303 Single-Cell Immune Map of Breast Carcinoma Reveals Diverse Phenotypic States Driven by the Tumor Microenvironment

Azizi, E.; Carr, A. J.; Plitas, G.; Cornish, A. E.; Konopacki, C.; Prabhakaran, S.; Nainys, J.; Wu, K.; Kiseliovas, V.; Setty, M.; Choi, K.; Dao, P.; Mazutis, L.; Rudensky, A. Y.; Pe'er, D.

10.1101/221994 — immunology — Posted on 2017-11-25

304 A Computational Model for the Evaluation of Complement System Regulation under Homeostasis, Disease, and Drug Intervention

Zewde, N.; Morikis, D.

10.1101/225029 — immunology — Posted on 2017-11-25

305 The standard genetic code facilitates exploration of the space of functional nucleotide sequences

Tripathi, S.; Deem, M.

10.1101/225003 — evolutionary biology — Posted on 2017-11-25

306 Modularity of the metabolic gene network as a prognostic biomarker for hepatocellular carcinoma

Ye, F.; Jia, D.; Lu, M.; Levine, H.; Deem, M.

10.1101/224998 — cancer biology — Posted on 2017-11-25

307 Interaction of lecithin-cholesterol acyltransferase with lipid surfaces and apolipoprotein A-I derived peptides: implications for the cofactor mechanism of apolipoprotein A-I

Casteleijn, M. G.; Parkkila, P.; Viitala, T.; Koivuniemi, A.

10.1101/225037 — biophysics — Posted on 2017-11-25

308 Functional Plasticity of the gut and the Malpighian tubules underlies cold acclimation and mitigates cold-induced hyperkalemia in Drosophila melanogaster

Yerushalmi, G. Y.; Misyura, L.; MacMillan, H. A.; Donini, A.

10.1101/224832 — zoology — Posted on 2017-11-24

309 Brain-Computer Interfaces for Post-Stroke Motor Rehabilitation: A Meta-Analysis

Cervera, M. A.; Soekadar, S. R.; Ushiba, J.; Millan, J. d. R.; Liu, M.; Birbaumer, N.; Garipelli, G.

10.1101/224618 — neuroscience — Posted on 2017-11-24

310 Is the LAN effect in morphosyntactic processing an ERP artifact?

Caffarra, S.; Mendoza, M.; Davidson, D.

10.1101/218594 — neuroscience — Posted on 2017-11-24

311 Two-Photon Imaging of Striatum Demonstrates Distinct Functions for Striosomes and Matrix in Reinforcement Learning

Bloem, B.; Huda, R.; Sur, M.; Graybiel, A. M.

10.1101/199497 — neuroscience — Posted on 2017-11-24

312 Sensory cortex is optimised for prediction of future input

Singer, Y.; Teramoto, Y.; Willmore, B.; Schnupp, J. W. H.; King, A. J.; Harper, N. S.

10.1101/224758 — neuroscience — Posted on 2017-11-24

313 Antigen B from Echinococcus granulosus enters mammalian cells by endocytic pathways

da Silva, E. D.; Cancela, M.; Monteiro, K. M.; Ferreira, H. B.; Zaha, A.

10.1101/224691 — molecular biology — Posted on 2017-11-24

314 Determinants of Transcription Initiation Directionality in Metazoans

Ibrahim, M. M.; Karabacak, A.; Glahs, A.; Kolundzic, E.; Hirsekorn, A.; Carda, A.; Tursun, B.; Zinzen, R. P.; Lacadie, S. A.; Ohler, U.

10.1101/224642 — molecular biology — Posted on 2017-11-24

315 Population level mitogenomics of the long-lived Greater Mouse-eared bat, Myotis myotis, reveals dynamic heteroplasmy and challenges the Free Radical Theory of Ageing

Jebb, D.; Foley, N. M.; Whelan, C. V.; Touzalin, F.; Puechmaille, S. J.; Teeling, E. C.

10.1101/224592 — genomics — Posted on 2017-11-24

316 A genome-wide association study for host resistance to Ostreid Herpesvirus in Pacific oysters (Crassostrea gigas)

Gutierrez, A.; Bean, T. P.; Hooper, C.; Stenton, C. A.; Sanders, M. B.; Paley, R. K.; Rastas, P.; Bryrom, M.; Matika, O.; Houston, R. D.

10.1101/223032 — genomics — Posted on 2017-11-24

317 Paleocene origin of the Neotropical lineage of cleptoparasitc bees Ericrocidini-Rhathymini (Hymenoptera, Apidae)

Martins, A. C.; da Luz, D. R.; Melo, G. A.

10.1101/224683 — evolutionary biology — Posted on 2017-11-24

318 From tree tops to the ground: reversals to terrestrial habit in Galeandra orchids (Epidendroideae: Catasetinae)

Martins, A. C.; Bochorny, T.; Perez-Escobar, O. A.; Chomicki, G.; Monteiro, S. H.; Smidt, E.

10.1101/224709 — evolutionary biology — Posted on 2017-11-24

319 Death and population dynamics affect mutation rate estimates and evolvability under stress in bacteria

Frenoy, A.; Bonhoeffer, S.

10.1101/224675 — evolutionary biology — Posted on 2017-11-24

320 Effects of increased N and P availability on biomass allocation and root carbohydrate reserves differ between N-fixing and non-N-fixing savanna tree seedlings

Varma, V.; Catherin, A. M.; Sankaran, M.

10.1101/224188 — ecology — Posted on 2017-11-24

321 Re-arrangements in the cytoplasmic distribution of small RNAs following the maternal-to-zygotic transition in Drosophila embryos

Cosacak, M. I.; Yigit, H.; Akgul, B.

10.1101/224626 — developmental biology — Posted on 2017-11-24

322 Altered hsrω lncRNA levels in activated Ras background further enhance Ras activity in Drosophila eye and induces more R7 photoreceptors

Lakhotia, S. C.; Ray, M.

10.1101/224543 — cell biology — Posted on 2017-11-24

323 The urinary microbiome associated with bladder cancer

Bucevic Popovic, V.; Situm, M.; Chow, C.-E. T.; Chan, L. S.; Roje, B.; Terzic, J.

10.1101/224667 — cancer biology — Posted on 2017-11-24

324 The MYC antagonist MNT autoregulates its expression and supports proliferation in MAX deficient cells

Lafita-Navarro, M. C.; Liano-Pons, J.; Quintanilla, A.; Varela, I.; Ourique, F.; Bretones, G.; Blanco, R.; Aresti, J.; Carroll, P.; Hurlin, P.; Eisenman, R. N.; Delgado, M. D.; Leon, J.

10.1101/212944 — cancer biology — Posted on 2017-11-24

325 DHSpred: support-vector-machine-based human DNase I hypersensitive sites prediction using the optimal features selected by random forest

Manavalan, B.; Shin, T. H.; Lee, G.

10.1101/224527 — bioinformatics — Posted on 2017-11-24

326 VarExp: Estimating variance explained by Genome-Wide GxE summary statistics

Laville, V.; Bentley, A.; Prive, F.; Zhu, X.; Gauderman, W.; Winkler, T.; Province, M.; Rao, D.; Aschard, H.; CHARGE Gene-Lifestyle Interactions Working Group,

10.1101/224634 — bioinformatics — Posted on 2017-11-24

327 Automated evaluation of quaternary structures from protein crystals

Bliven, S.; Lafita, A.; Parker, A.; Capitani, G.; Duarte, J. M.

10.1101/224717 — bioinformatics — Posted on 2017-11-24

328 MEGAN-LR: New algorithms allow accurate binning and easy interactive exploration of metagenomic long reads and contigs

Huson, D.; Albrecht, B.; Bagci, C.; Bessarab, I.; Gorska, A.; Jolic, D.; Williams, R. B. H.

10.1101/224535 — bioinformatics — Posted on 2017-11-24

329 Quaternary structure evaluation tool for protein assemblies

Korkmaz, S.; Duarte, J. M.; Prlic, A.; Goksuluk, D.; Zararsiz, G.; Saracbasi, O.; Burley, S. K.; Rose, P. W.

10.1101/224196 — bioinformatics — Posted on 2017-11-24

330 Avian thermoregulation in the heat: phylogenetic variation among avian orders in evaporative cooling capacity and heat tolerance

Smit, B.; Whitfield, M. C.; Talbot, W. A.; Gerson, A. R.; McKechnie, A. E.; Wolf, B. O.

10.1101/211730 — zoology — Posted on 2017-11-24

331 Mapping the phenotypic repertoire of the cytoplasmic 2-Cys peroxiredoxin - thioredoxin system. 1. Understanding commonalities and differences among cell types.

Selvaggio, G.; Coelho, P. M. B. M.; Salvador, A.

10.1101/224428 — systems biology — Posted on 2017-11-24

332 DNA Damage Induced Chromosomal Instability. Computational modeling view.

Eidelman, Y.; Slanina, S.; Pyatenko, V.; Andreev, S.

10.1101/218826 — systems biology — Posted on 2017-11-24

333 Naked mole-rat transcriptome signatures of socially-suppressed sexual maturation and links of reproduction to aging

Bens, M.; Szafranski, K.; Holtze, S.; Sahm, A.; Groth, M.; Kestler, H. A.; Hildebrandt, T. B.; Platzer, M.

10.1101/221333 — systems biology — Posted on 2017-11-24

334 Quantifying relationships between chromosome organization and chromosomal aberrations

Eidelman, Y.; Slanina, S.; Andreev, S.

10.1101/223859 — systems biology — Posted on 2017-11-24

335 A comparison of root and shoot hydraulics, aquaporin expression and leaf gas exchange between two grapevine cultivars reveals differences in hydraulic control mediated by aquaporins

Dayer, S.; Scharwies, J. D.; Ramesh, S.; Sullivan, W.; Doerflinger, F.; Pagay, V.; Tyerman, S. D.

10.1101/224212 — plant biology — Posted on 2017-11-24

336 Speaker gaze increases information coupling between infant and adult brains

Leong, V.; Byrne, E.; Clackson, K.; Georgieva, S.; Lam, S.; Wass, S.

10.1101/108878 — neuroscience — Posted on 2017-11-24

337 Unfolding the hippocampus: An intrinsic coordinate system for subfield segmentations and quantitative mapping

DeKraker, J.; Ferko, K. M.; Lau, J. C.; Köhler, S.; Khan, A. R.

10.1101/146878 — neuroscience — Posted on 2017-11-24

338 A Retina Model Based on Convolutions on the GPU

Huth, J.; Masquelier, T.; Arleo, A.

10.1101/169284 — neuroscience — Posted on 2017-11-24

339 A functioning model of human time perception

Roseboom, W.; Fountas, Z.; Nikiforou, K.; Bhowmik, D.; Shanahan, M.; Seth, A. K.

10.1101/172387 — neuroscience — Posted on 2017-11-24

340 Cell-Type Specific Interrogation of Amygdala Drd2-Expressing Neurons Identifies Targets for Pharmacological Modulation of Fear Extinction

Ressler, K. J.; Mccullough, K.; Daskalakis, N. P.; Gafford, G.; Morrison, F. G.

10.1101/224261 — neuroscience — Posted on 2017-11-24

341 Dorsomedial prefrontal cortex activity during reinforcement learning discriminates response to Cognitive Behavioural Therapy in depression.

Queirazza, F.; Fouragnan, E.; Steele, J. D.; Cavanagh, J.; Philiastides, M.

10.1101/224410 — neuroscience — Posted on 2017-11-24

342 From image formation to image representation: the human visual system preserves the hierarchy of 2-dimensional pattern regularity

Kohler, P. J.; Norcia, A. M.

10.1101/223743 — neuroscience — Posted on 2017-11-24

343 Alpha/beta power compresses time in sub-second temporal judgments

van Viegen, T.; Charest, I.; Jensen, O.; Mazaheri, A.

10.1101/224386 — neuroscience — Posted on 2017-11-24

344 Self-organised attractor dynamics in the developing head direction circuit.

Bassett, J. P.; Wills, T. J.; Cacucci, F.

10.1101/221028 — neuroscience — Posted on 2017-11-24

345 Bidirectional Cycling Dynamics of Living Neuronal Networks in Vitro

Gladkov, A.; Grinchuk, O.; Pigareva, Y.; Mukhina, I.; Kazantsev, V.; Pimashkin, A.

10.1101/223230 — neuroscience — Posted on 2017-11-24

346 Unmasking cellular response of a bloom-forming alga to virus infection by resolving expression profiling at a single-cell level

Rosenwasser, S.; Frada, M. J.; Pilzer, D.; Rotkopf, R.; Vardi, A.

10.1101/186981 — microbiology — Posted on 2017-11-24

347 5-Formylcytosine controls nucleosome positioning through covalent histone-DNA interaction

Raiber, E.-A.; Portella, G.; Martinez Cuesta, S.; Hardisty, R.; Murat, P.; Li, Z.; Iurlaro, M.; Dean, W.; Spindel, J.; Beraldi, D.; Dawson, M.; Reik, W.; Balasubramanian, S.

10.1101/224444 — genomics — Posted on 2017-11-24

348 Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

Natarajan, P.; Peloso, G. M.; Zekavat, S. M.; Montasser, M.; Ganna, A.; Chaffin, M.; Khera, A. V.; Zhao, W.; Bloom, J. M.; Engreitz, J. M.; Ernst, J.; O'Connell, J. R.; Ruotsalainen, S. E.; Alver, M.; Manichaikul, A.; Johnson, W. C.; Perry, J. A.; Poterba, T.; Seed, C.; Surakka, I. L.; Esko, T.; Ripatti, S.; Salomaa, V.; Correa, A.; Vasan, R. S.; Kellis, M.; Neale, B. M.; Lander, E. S.; Abecassis, G.; Mitchell, B.; Rich, S. S.; Wilson, J. G.; Cupples, L. A.; Rotter, J. I.; NHLBI TOPMed Lipids Working Group, ; Willer, C. J.; Kathiresan, S.

10.1101/224378 — genomics — Posted on 2017-11-24

349 Whole genome hybrid assembly and protein-coding gene annotation of the entirely black native Korean chicken breed Yeonsan Ogye

Sohn, J.-i.; Nam, K.; Kim, J.-M.; Lim, D.; Lee, K.-T.; Do, Y. J.; Cho, C. Y.; Kim, N.; Nam, J.-W.; Chae, H.-H.

10.1101/224311 — genomics — Posted on 2017-11-24

350 Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

Zhou, W.; Nielsen, J. B.; Fritsche, L. G.; Dey, R.; Elvestad, M. B.; Wolford, B. N.; LeFaive, J.; VandeHaar, P.; Gifford, A.; Bastarache, L. A.; Wei, W.-Q.; Denny, J. C.; Lin, M.; Hveem, K.; Kang, H. M.; Abecasis, G. R.; Willer, C. J.; Lee, S.

10.1101/212357 — genomics — Posted on 2017-11-24

351 Weighted burden analysis of exome-sequenced case-control sample implicates synaptic genes in schizophrenia aetiology

Curtis, D.; Coelewij, L.; Liu, S.-H.; Humphrey, J.; Mott, R.

10.1101/203521 — genetics — Posted on 2017-11-24

352 A reassessment of DNA immunoprecipitation-based genomic profiling

Lentini, A.; Lagerwall, C.; Vikingsson, S.; Mjoseng, H. K.; Douvlataniotis, K.; Vogt, H.; Green, H.; Meehan, R. R.; Benson, M.; Nestor, C. E.

10.1101/224279 — genetics — Posted on 2017-11-24

353 Tracing the genetic etiology of cardiovascular disease using a hierarchy of common genetic variants derived from patient subgroups stratified by differential levels in severity

Fatakia, S. N.

10.1101/213124 — genetics — Posted on 2017-11-24

354 Predicting microbial relative growth in a mixed culture from growth curve data

Ram, Y.; Dellus-Gur, E.; Bibi, M.; Obolski, U.; Berman, J.; Hadany, L.

10.1101/022640 — evolutionary biology — Posted on 2017-11-24

355 Complex models of sequence evolution require accurate estimators as exemplified with the invariable site plus Gamma model

Nguyen, L. T.; von Haeseler, A.; Minh, B. Q.

10.1101/185652 — evolutionary biology — Posted on 2017-11-24

356 Prevalence of loss-of-function alleles does not correlate with lifetime fecundity and other life-history traits in metazoans

Bezmenova, A. V.; Bazykin, G. A.; Kondrashov, A. S.

10.1101/224436 — evolutionary biology — Posted on 2017-11-24

357 The role of chromosomal inversions in speciation

Fuller, Z.; Leonard, C.; Young, R.; Schaeffer, S.; Phadnis, N.

10.1101/211771 — evolutionary biology — Posted on 2017-11-24

358 The feasibility and stability of large complex biological networks: a random matrix approach

Stone, L.

10.1101/223651 — ecology — Posted on 2017-11-24

359 The HoxD Cluster is a Dynamic and Resilient TAD Boundary Controling the Segregation of Antagonistic Regulatory Landscapes

Rodriguez-Carballo, E.; Lopez-Delisle, L.; Zhan, Y.; Fabre, P.; Beccari, L.; El-Idrissi, I.; Nguyen Huynh, T. H.; Ozadam, H.; Dekker, J.; Duboule, D.

10.1101/193706 — developmental biology — Posted on 2017-11-24

360 Endocytosis caused by liquid-liquid phase separation of proteins

Bergeron-Sandoval, L.-P.; Heris, H. K.; Hendricks, A. G.; Ehrlicher, A. J.; Francois, P.; Pappu, R. V.; Michnick, S. W.

10.1101/145664 — cell biology — Posted on 2017-11-24

361 A urine-dependent human urothelial organoid offers a promising alternative to rodent models of infection

Horsley, H.; Dharmasena, D.; Malone-Lee, J.; Rohn, J. L.

10.1101/152033 — cell biology — Posted on 2017-11-24

362 Cryo-ET reveals nucleosome reorganization in condensed mitotic chromosomes in vivo

Cai, S.; Chen, C.; Tan, Z. Y.; Huang, Y.; Shi, J.; Gan, L.

10.1101/178996 — cell biology — Posted on 2017-11-24

363 Quantitative relationships for radiation induced chromosome instability: data analysis

Eidelman, Y.; Slanina, S.; Pyatenko, V.; Khvostunov, I.; Andreev, S.

10.1101/224006 — cancer biology — Posted on 2017-11-24

364 Euplotid: A quantized geometric model of the eukaryotic cell

Borges-Rivera, D.

10.1101/170159 — biophysics — Posted on 2017-11-24

365 Is chaos making a difference? Synchronization transitions in chaotic and non-chaotic neuronal networks

xu, k.; Maidana, J. P.; Castro, S.; Orio, P.

10.1101/224451 — biophysics — Posted on 2017-11-24

366 Interoperable and scalable metabolomics data analysis with microservices

Emami Khoonsari, P.; Moreno, P.; Bergmann, S.; Burman, J.; Capuccini, M.; Carone, M.; Cascante, M.; de Atauri, P.; Foguet, C.; Gonzalez-Beltran, A.; Hankemeier, T.; Haug, K.; He, S.; Herman, S.; Johnson, D.; Kale, N.; Larsson, A.; Neumann, S.; Peters, K.; Pireddu, L.; Rocca-Serra, P.; Roger, P.; Rueedi, R.; Ruttkies, C.; Sadawi, N.; Salek, R. M.; Sansone, S.-A.; Schober, D.; Selivanov, V.; Thevenot, E. A.; van Vliet, M.; Zanetti, G.; Steinbeck, C.; Kultima, K.; Spjuth, O.

10.1101/213603 — bioinformatics — Posted on 2017-11-24

367 REASSESSING THE REVOLUTIONS RESOLUTIONS

van Heel, M.; Schatz, M.

10.1101/224402 — biochemistry — Posted on 2017-11-24

368 C-terminal truncation of Pik3r1 in mice models human lipodystrophic insulin resistance uncoupled from dyslipidemia

Kwok, A.; Zvetkova, I.; Virtue, S.; Huang-Doran, I.; Tomlinson, P.; Bulger, D. A.; Hart, D.; Knox, R.; Franks, S.; Voshol, P.; Vidal-Puig, A.; Sferruzzi-Perri, A.; Jensen, J.; O'Rahilly, S.; Semple, R. K.

10.1101/224485 — biochemistry — Posted on 2017-11-24

369 Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule

Tsai, J. C.; Miller-Vedam, L. E.; Anand, A. A.; Jaishankar, P.; Nguyen, H. C.; Renslo, A. R.; Frost, A.; Walter, P.

10.1101/222257 — biochemistry — Posted on 2017-11-24

370 Experimental evidence that female rhesus macaques (Macaca mulatta) perceive variation in male facial masculinity

Rosenfield, K. A.; Semple, S.; Georgiev, A. V.; Maestripieri, D.; Higham, J. P.; Dubuc, C.

10.1101/222810 — animal behavior and cognition — Posted on 2017-11-24

371 A systematic review of sample size and power in leading neuroscience journals

Carter, A. R.; Tilling, K.; Munafo, M. R.

10.1101/217596 — scientific communication and education — Posted on 2017-11-23

372 Cooperating H3N2 influenza virus variants are not detectable in primary clinical samples

Xue, K. S.; Greninger, A. L.; Perez-Osorio, A.; Bloom, J. D.

10.1101/223677 — microbiology — Posted on 2017-11-23

373 Habitat complexity mediates benthic predator-prey interactions in Chesapeake Bay

Glaspie, C. N.; Seitz, R. D.

10.1101/224089 — ecology — Posted on 2017-11-23

374 CaDrA: A computational framework for performing candidate driver analyses using binary genomic features

Kartha, V. K.; Kern, J. G.; Sebastiani, P.; Zhang, L.; Varelas, X.; Monti, S.

10.1101/221846 — bioinformatics — Posted on 2017-11-23

375 Single-cell quantitative analysis of skeletal muscle cell population dynamicsduring regeneration and ageing

Petrilli, L. L.; Spada, F.; Fuoco, C.; Micarelli, E.; Reggio, A.; Rosina, M.; Gargioli, C.; Castagnoli, L.; Cesareni, G.

10.1101/222158 — systems biology — Posted on 2017-11-23

376 Ranked tree shapes, non-random extinctions and the loss of phylogenetic diversity

Maliet, O.; Gascuel, F.; Lambert, A.

10.1101/224295 — evolutionary biology — Posted on 2017-11-23

377 Cyclic nature of the REM-like state in the cuttlefish Sepia officinalis

Iglesias, T. L.; Boal, J.; Frank, M.; Zeil, J.; Hanlon, R.

10.1101/224220 — animal behavior and cognition — Posted on 2017-11-23

378 Chromatin-release of the long ncRNA A-ROD is required for transcriptional activation of its target gene DKK1

Ntini, E.; Liz, J.; Muino, J. M.; Marsico, A.; Oerom, U. A.

10.1101/224360 — molecular biology — Posted on 2017-11-23

379 Previously Hidden Dynamics at the TCR-pMHC Interface Revealed

Fodor, J.; Riley, B. T.; Borg, N. A.; Buckle, A. M.

10.1101/223628 — immunology — Posted on 2017-11-23

380 Allosteric effects in a catalytically impaired variant of the enzyme Cyclophilin A are unrelated to millisecond time scale motions

Wapeesittipan, P.; Mey, A.; Walkinshaw, M.; Michel, J.

10.1101/224329 — biophysics — Posted on 2017-11-23

381 Balance between resource supply and demand determines nutrient limitation of primary productivity in the ocean

Hagstrom, G. I.; Levin, S. A.; Martiny, A.

10.1101/064543 — ecology — Posted on 2017-11-23

382 Neuronal resonance in the theta (4-10 Hz) frequency range is modulated by dynamic changes in the input resistance

Vera, J.; Pereira, U.; Reynaert, B.; Bacigalupo, J.; Sanhueza, M.

10.1101/224253 — neuroscience — Posted on 2017-11-23

383 A Phylogenomic Study Quantifies Competing Mechanisms for Pseudogenization in Prokaryotes

Avni, E.; Montoya, D.; Lopez, D.; Modlin, R.; Pellegrini, M.; Snir, S.

10.1101/224238 — evolutionary biology — Posted on 2017-11-23

384 A comparison of root and shoot hydraulics, aquaporin expression and leaf gas exchange between two grapevine cultivars reveals differences in hydraulic control mediated by aquaporins

Dayer, S.; Scharwies, J. D.; Ramesh, S.; Sullivan, W.; Doerflinger, F.; Pagay, V.; Tyerman, S. D.

10.1101/224212 — plant biology — Posted on 2017-11-23

385 Sensitivity to Pain Expectations: A Bayesian Model of Individual Differences

Hoskin, R.; Berzuini, C. C.; Acosta-Kane, D.; El-Deredy, W.; Guo, H.; Talmi, D.

10.1101/176172 — neuroscience — Posted on 2017-11-23

386 Signaling-dependent control of apical membrane size and self-renewal in rosette-stage human neuroepithelial stem cells

Medelnik, J.-P.; Roensch, K.; Okawa, S.; del Sol, A.; Chara, O.; Mchedlishvili, L.; Tanaka, E.

10.1101/222125 — neuroscience — Posted on 2017-11-23

387 Analysis of fMRI data using noise-diffusion network models: a new covariance-coding perspective

Gilson, M.

10.1101/223784 — neuroscience — Posted on 2017-11-23

388 Real-Time Tracking of Selective Auditory Attention from M/EEG: A Bayesian Filtering Approach

Miran, S.; Akram, S.; Sheikhattar, A.; Simon, J. Z.; Zhang, T.; Babadi, B.

10.1101/222661 — neuroscience — Posted on 2017-11-23

389 Expressed Exome Capture Sequencing (EecSeq): a method for cost-effective exome sequencing for all organisms with or without genomic resources

Puritz, J. B.; Lotterhos, K. E.

10.1101/223735 — genomics — Posted on 2017-11-23

390 A new standard for crustacean genomes: the highly contiguous, annotated genome assembly of the clam shrimp Eulimnadia texana reveals HOX gene order and identifies the sex chromosome

Baldwin-Brown, J. G.; Weeks, S. C.; Long, A. D.

10.1101/222869 — genomics — Posted on 2017-11-23

391 An interlaboratory study of complex variant detection

Lincoln, S. E.; Zook, J. M.; Chowdhury, S.; Mahamdallie, S.; Fellowes, A.; Klee, E. W.; Truty, R.; Huang, C.; Tomson, F. L.; Cleveland, M. H.; Vallone, P. M.; Ding, Y.; Seal, S.; DeSilva, W.; Garlick, R. K.; Salit, M.; Rahman, N.; Kingsmore, S. F.; Aradhya, S.; Nussbaum, R. L.; Ferber, M. J.; Shirts, B. H.

10.1101/218529 — genetics — Posted on 2017-11-23

392 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal

Jeong, C.; Witonsky, D. B.; Basnyat, B.; Neupane, M.; Beall, C. M.; Childs, G.; Craig, S. R.; Novembre, J.; Di Rienzo, A.

10.1101/223081 — genetics — Posted on 2017-11-23

393 The origin and remolding of genomic islands of differentiation in the European sea bass

Duranton, M.; Allal, F.; Fraïsse, C.; Bierne, N.; Bonhomme, F.; Gagnaire, P.-A.

10.1101/223750 — evolutionary biology — Posted on 2017-11-23

394 Pooled population resequencing of clam shrimp (Eulimnadia texana) from different vernal pools reveals signatures of local adaptation

Baldwin-Brown, J. G.; Long, A. D.

10.1101/223602 — evolutionary biology — Posted on 2017-11-23

395 Quaternary structure evaluation tool for protein assemblies

Korkmaz, S.; Duarte, J. M.; Prlic, A.; Goksuluk, D.; Zararsiz, G.; Saracbasi, O.; Burley, S. K.; Rose, P. W.

10.1101/224196 — bioinformatics — Posted on 2017-11-23

396 Non-coding Transcriptome Maps Across Twenty Tissues of the Korean Black Chicken, Yeonsan Ogye

Hong, H.; Chai, H.-H.; Nam, K.; Lim, D.; Lee, K.-T.; Do, Y. J.; Cho, C.-Y.; Nam, J.-W.

10.1101/223644 — bioinformatics — Posted on 2017-11-23

397 Variance reduction for antithetic integral control of stochastic reaction networks

Briat, C.; Gupta, A.; Khammash, M.

10.1101/223917 — systems biology — Posted on 2017-11-22

398 Cerebral Autoregulation, CSF outflow resistance and outcome following CSF diversion in Normal Pressure Hydrocephalus.

Lalou, A. D.; Czosnyka, M.; Donnelly, J.; Peter, J. D.; Nabbanja, E.; Keong, N. C.; Garnett, M. R.; Czosnyka, Z.

10.1101/223867 — neuroscience — Posted on 2017-11-22

399 Effects of background and contour luminance on the hue and brightness of the Watercolor effect

Gerardin, P.; Dojat, M.; Knoblauch, K.; Devinck, F.

10.1101/223792 — neuroscience — Posted on 2017-11-22

400 Immediate effects of psychosocial stress on attention depend on subjective experience and not directly on stress-related physiological changes

Palacios-Garcia, I.; Villena-Gonzalez, M.; Campos-Arteaga, G.; Artigas-Vergara, C.; Jaramillo, K.; Lopez, V.; Rodriguez, E.; Silva, J.

10.1101/223909 — neuroscience — Posted on 2017-11-22

401 Advanced NeuroGPS-Tree: dense reconstruction of brain-wideneuronal population close to ground truth

Zhou, H.; Li, S.; Feng, X.; Han, J.; Kang, H.; Chen, Y.; Li, Y.; Li, J.; Su, L.; Li, A.; Gong, H.; Zeng, S.; Quan, T.; Luo, Q.

10.1101/223834 — neuroscience — Posted on 2017-11-22

402 Task-dependent modulation of spinal and transcortical stretch reflexes linked to motor learning rate

Dimitriou, M.

10.1101/223842 — neuroscience — Posted on 2017-11-22

403 Translational control plays an important role in the adaptive heat-shock response of Streptomyces coelicolor

Bucca, G.; Pothi, R.; Hesketh, A.; Moller-Levet, C.; Hodgson, D. A.; Laing, E. E.; Stewart, G. R.; Smith, C. P.

10.1101/223925 — genomics — Posted on 2017-11-22

404 Effective population size and durability of plant resistances in the potato cyst nematode Globodera pallida

Montarry, J.; Petit, E. J.; Bardou-Valette, S.; Mabon, R.; Jan, P.-L.; Fournet, S.; Grenier, E.

10.1101/223826 — evolutionary biology — Posted on 2017-11-22

405 Aiptasia as a model to study metabolic diversity and specificity in cnidarian-dinoflagellate symbioses

Raedecker, N.; Raina, J.-B.; Pernice, M.; Perna, G.; Guagliardo, P.; Killburn, M.; Aranda, M.; Voolstra, C. R.

10.1101/223933 — physiology — Posted on 2017-11-22

406 The temporal evolution of conceptual object representations revealed through models of behavior, semantics and deep neural networks

Bankson, B. B.; Hebart, M. N.; Groen, I. I. A.; Baker, C. I.

10.1101/223990 — neuroscience — Posted on 2017-11-22

407 Spliceosome profiling visualizes the operations of a dynamic RNP in vivo at nucleotide resolution

Burke, J.; Longhurst, A.; Merkurjev, D.; Sales-Lee, J.; Rao, B.; Moresco, J.; Yates, J.; Li, J. J.; Madhani, H. D.

10.1101/224170 — molecular biology — Posted on 2017-11-22

408 Placenta DNA Methylation Adaptation to Maternal Glucose Tolerance in Pregnancy

Cardenas, A.; Gagne-Ouellet, V.; Allard, C.; Brisson, D.; Perron, P.; Bouchard, L.; Hivert, M.-F.

10.1101/224139 — genomics — Posted on 2017-11-22

409 Nextstrain: real-time tracking of pathogen evolution

Hadfield, J.; Megill, C.; Bell, S. M.; Huddleston, J.; Potter, B.; Callender, C.; Sagulenko, P.; Bedford, T.; Neher, R. A.

10.1101/224048 — evolutionary biology — Posted on 2017-11-22

410 Impacts of predators, habitat, recruitment, and disease on soft-shell clams Mya arenaria and stout razor clams Tagelus plebeius in Chesapeake Bay

Glaspie, C. N.; Seitz, R. D.; Ogburn, M. B.; Dungan, C. F.; Hines, A. H.

10.1101/224071 — ecology — Posted on 2017-11-22

411 The perfect storm: Extreme weather drives and predation maintains phase shift in dominant Chesapeake Bay bivalve

Glaspie, C. N.; Seitz, R. D.; Lipcius, R. N.

10.1101/224097 — ecology — Posted on 2017-11-22

412 EB1 binding provides a diffusion trap mechanism regulating STIM1 localization and Ca2+ signaling

Chang, C.-L.; Chen, Y.-J.; Liou, J.

10.1101/224162 — cell biology — Posted on 2017-11-22

413 Mechanochemical Coupling and Bi-Phasic Force-Velocity Dependence in the Ultra-Fast Ring ATPase SpoIIIE

Liu, N.; Chistol, G.; Cui, Y.; Bustamante, C.

10.1101/224022 — biochemistry — Posted on 2017-11-22

414 Quantifying relationships between chromosome organization and chromosomal aberrations

Eidelman, Y.; Slanina, S.; Andreev, S.

10.1101/223859 — systems biology — Posted on 2017-11-22

415 DNA Damage Induced Chromosomal Instability. Computational modeling view.

Eidelman, Y.; Slanina, S.; Pyatenko, V.; Andreev, S.

10.1101/218826 — systems biology — Posted on 2017-11-22

416 Expansion and diversification of the gibberellin receptor GIBBERELLIN INSENSITIVE DWARF1 (GID1) family in land plants

Gazara, R. K.; Moharana, K. C.; Bellieny-Rabelo, D.; Venancio, T. M.

10.1101/221937 — plant biology — Posted on 2017-11-22

417 Fast voltage sensitivity in retinal pigment epithelium: sodium channels and their novel role in phagocytosis

Johansson, J. K.; Ihalainen, T. O.; Skottman, H.; Nymark, S.

10.1101/223719 — physiology — Posted on 2017-11-22

418 Phenotyping ciliary dynamics and coordination in response to CFTR-modulators in Cystic Fibrosis respiratory epithelial cells

Chioccioli, M.; Feriani, L.; Kotar, J.; Bratcher, P. E.; Cicuta, P.

10.1101/223024 — physiology — Posted on 2017-11-22

419 Classification and characterisation of brain network changes in chronic back pain: a multicenter study.

Mano, H.; Kotecha, G.; Leibnitz, K.; Matsubara, T.; Nakae, A.; Shenker, N.; Shibata, M.; Voon, V.; Yoshida, W.; Lee, M.; Yanagida, T.; Kawato, M.; Rosa, M.; Seymour, B.

10.1101/223446 — neuroscience — Posted on 2017-11-22

420 Cellular diversity of the somatosensory cortical map plasticity

Kole, K.; Scheenen, W.; Tiesinga, P.; Celikel, T.

10.1101/201293 — neuroscience — Posted on 2017-11-22

421 Network supporting contextual fear learning after dorsal hippocampal damage has increased dependence on retrosplenial cortex

Coelho, C. A. O.; Ferreira, T. L.; Soares, J. C. K.; Sato, J. R.; Oliveira, M. G. M.

10.1101/209866 — neuroscience — Posted on 2017-11-22

422 Developmental And Genetic Regulation Of The Human Cortex Transcriptome In Schizophrenia

Jaffe, A. E.; Straub, R. E.; Shin, J. H.; Tao, R.; Gao, Y.; Collado Torres, L.; Kam-Thong, T.; Xi, H. S.; Quan, J.; Chen, Q.; Colantuoni, C.; Ulrich, W. S.; Maher, B. J.; Deep-Soboslay, A.; The BrainSeq Consortium, ; Cross, A.; Brandon, N. J.; Leek, J. T.; Hyde, T. M.; Kleinman, J. E.; Weinberger, D. R.

10.1101/124321 — neuroscience — Posted on 2017-11-22

423 Decoding of neural data using cohomological learning

Rybakken, E.; Baas, N.; Dunn, B.

10.1101/222331 — neuroscience — Posted on 2017-11-22

424 Developing a low-cost milliliter-scale chemostat array for precise control of cellular growth

Skelding, D. H.; Hart, S. F. M.; Vidyasagar, T.; Pozhitkov, A. E.; Shou, W.

10.1101/223594 — microbiology — Posted on 2017-11-22

425 Single cell transcriptomics of regulatory T cells reveals trajectories of tissue adaptation

Miragaia, R. J.; Gomes, T.; Chomka, A.; Jardine, L.; Riedel, A.; Hegazy, A. N.; Lindeman, I.; Emerton, G.; Krausgruber, T.; Shields, J.; Haniffa, M.; Powrie, F.; Teichmann, S. A.

10.1101/217489 — immunology — Posted on 2017-11-22

426 Cyclin-Dependent Kinase Activity is Required for Type I Interferon Production

Cingoz, O.; Goff, S.

10.1101/224121 — immunology — Posted on 2017-11-22

427 RNA G-quadruplexes mark repressive upstream open reading frames in human mRNAs

Murat, P.; Marsico, G.; Herdy, B.; Ghanbarian, A.; Portella, G.; Balasubramanian, S.

10.1101/223073 — genomics — Posted on 2017-11-22

428 Genomic insights into the domestication of the chocolate tree, Theobroma cacao L.

Cornejo, O. E.; Yee, M.-C.; Dominguez, V.; Andrews, M.; Sockell, A.; Strandberg, E.; Livingstone, D.; Stack, C.; Romero, A.; Umaharan, P.; Royaert, S.; Tawari, N. R.; Pauline, N.; Schnell, R.; Wilbert, P.; Mockaitis, K.; Bustamante, C. D.; Motamayor, J. C.

10.1101/223438 — genomics — Posted on 2017-11-22

429 Genome-wide detection of genes under positive selection in worldwide populations of the barley scald pathogen

Mohd-Assaad, N.; McDonald, B. A.; Croll, D.

10.1101/223545 — genomics — Posted on 2017-11-22

430 A map of constrained coding regions in the human genome.

Havrilla, J. M.; Pedersen, B. S.; Layer, R. M.; Quinlan, A. R.

10.1101/220814 — genomics — Posted on 2017-11-22

431 Epigenome-wide association in adipose tissue from the METSIM cohort identifies novel loci and the involvement of adipocytes and macrophages in diabetes traits

Orozco, L.; Farrell, C.; Hale, C.; Rubbi, L.; Rinaldi, A.; Civelek, M.; Pam, C.; Lam, L.; Montoya, D.; Edillor, C.; Seldin, M.; Boehnke, M.; Mohlke, K.; Jacobsen, S.; Kuusisto, J.; Laakso, M.; Lusis, A.; Pellegrini, M.

10.1101/223495 — genetics — Posted on 2017-11-22

432 Phylogenetic analysis of West Nile Virus in Maricopa County, Arizona: Evidence for dynamic behavior of strains in two major lineages in the American Southwest

Hepp, C. M.; Cocking, J. H.; Valentine, M.; Young, S. J.; Damian, D.; Sheridan, K.; Fofanov, V. Y.; Busch, J. D.; Erickson, D. E.; Lancione, R. C.; Smith, K.; Will, J.; Townsend, J.; Keim, P. S.; Engelthaler, D. M.

10.1101/223503 — evolutionary biology — Posted on 2017-11-22

433 Ancestral genome estimation reveals the history of ecological diversification in Agrobacterium.

Lassalle, F.; Planel, R.; Penel, S.; Chapulliot, D.; Barbe, V.; Dubost, A.; Calteau, A.; Vallenet, D.; Mornico, D.; Bigot, T.; Gueguen, L.; Vial, L.; Muller, D.; Daubin, V.; Nesme, X.

10.1101/034843 — evolutionary biology — Posted on 2017-11-22

434 Pervasive correlated evolution in gene expression shapes cell type transcriptomes

Liang, C.; Musser, J. M.; Cloutier, A.; Prum, R.; Wagner, G.

10.1101/070060 — evolutionary biology — Posted on 2017-11-22

435 Time course analysis of the brain transcriptome during transitions between brood care and reproduction in the clonal raider ant

Libbrecht, R.; Oxley, P. R.; Kronauer, D. J.

10.1101/223255 — evolutionary biology — Posted on 2017-11-22

436 What can an evolutionary perspective on women’s health provide to the current public health paradigm? A case study on redefining thyroid cancer as a reproductive cancer

Fraser, A. G.

10.1101/222737 — evolutionary biology — Posted on 2017-11-22

437 Inferring Genetic Interactions From Comparative Fitness Data

Crona, K.; Gavryushkin, A.; Greene, D.; Beerenwinkel, N.

10.1101/137372 — evolutionary biology — Posted on 2017-11-22

438 The predictability of genomic changes underlying a recent host shift in Melissa blue butterflies

Chaturvedi, S.; Lucas, L. K.; Nice, C. C.; Fordyce, J. A.; Forister, M. L.; Gompert, Z.

10.1101/222703 — evolutionary biology — Posted on 2017-11-22

439 Determining whether a class of random graphs is consistent with an observed contact network

Nath, M.; Ren, Y.; Khorramzadeh, Y.; Eubank, S.

10.1101/168047 — epidemiology — Posted on 2017-11-22

440 An agent-based model of cattle grazing toxic Geyer’s larkspur

Jablonski, K.; Boone, R. B.; Meiman, P. J.

10.1101/218032 — ecology — Posted on 2017-11-22

441 From pioneer to repressor: Bimodal foxd3 activity dynamically remodels neural crest regulatory landscape in vivo

Gavriouchkina, D.; Williams, R. M.; Lukoseviciute, M.; Hochgreb-Hagele, T.; Senanayake, U.; Chong-Morrison, V.; Thongjuea, S.; Repapi, E.; Mead, A.; Sauka-Spengler, T.

10.1101/213611 — developmental biology — Posted on 2017-11-22

442 Skeletal muscle fibro-adipogenic progenitors of dystrophic mice are insensitive to NOTCH-dependent regulation of adipogenesis

Marinkovic, M.; Sacco, F.; Spada, F.; Petrilli, L. L.; Fuoco, C.; Micarelli, E.; Pavlidou, T.; Castagnoli, L.; Mann, M.; Gargioli, C.; Cesareni, G.

10.1101/223370 — cell biology — Posted on 2017-11-22

443 Evaluation of anti insulin receptor antibodies as potential novel therapies for human insulin receptoropathy

Brierley, G.; Siddle, K.; Semple, R. K.

10.1101/223883 — cell biology — Posted on 2017-11-22

444 Nuclear Export Through Nuclear Envelope Remodeling in Saccharomyces cerevisiae

Ding, B.; Mirza, A. M.; Ashley, J.; Budnik, V.; Munson, M.

10.1101/224055 — cell biology — Posted on 2017-11-22

445 BMPR2 inhibits activin- and BMP-signaling via wild type ALK2

Olsen, O. E.; Sankar, M.; Elsaadi, S.; Hella, H.; Buene, G.; Darvekar, S. R.; Misund, K.; Katagiri, T.; Holien, T.

10.1101/222406 — cell biology — Posted on 2017-11-22

446 Quantitative relationships for radiation induced chromosome instability: data analysis

Eidelman, Y.; Slanina, S.; Pyatenko, V.; Khvostunov, I.; Andreev, S.

10.1101/224006 — cancer biology — Posted on 2017-11-22

447 BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous cell carcinoma

Lazarus, K. A.; Hadi, F.; Zambon, E.; Bach, K.; Santolla, M.-F.; Watson, J. K.; Correia, L. L.; Das, M.; Ugur, R.; Pensa, S.; Becker, L.; Campos, L. S.; Ladds, G.; Liu, P.; Evan, G.; McCaughan, F.; Le Quesne, J.; Lee, J.-H.; Calado, D.; Khaled, W. T.

10.1101/223776 — cancer biology — Posted on 2017-11-22

448 Detection of small breast tumors using tumor penetrating-polymersomes engineered to target p32 protein

Simon-Gracia, L.; Scodeller, P.; Salzar Fuentes, S.; Gomez Vallejo, V.; Rios, X.; San Sebastian, E.; Di Silvio, D.; Suck, M.; De Lorenzi, F.; Yokota Rizzo, L.; von Stillfried, S.; Kilk, K.; Lammers, T.; Moya, S. E.; Teesalu, T.

10.1101/187716 — cancer biology — Posted on 2017-11-22

449 Characterizing Cancer Drug Response and Biological Correlates: A Geometric Network Approach

Pouryahya, M.; Oh, J. H.; Mathews, J.; Deasy, J.; Tannenbaum, A. R.

10.1101/222943 — cancer biology — Posted on 2017-11-22

450 miR-16 suppresses growth of rhabdoid tumor cells

Stroup, E. K.; Yeu, Y.; Budhipramono, A.; Hwang, T. H.; Rakheja, D.; Erdreich-Epstein, A.; Laetsch, T. W.; Amatruda, J. F.; Chen, K. S.

10.1101/219709 — cancer biology — Posted on 2017-11-22

451 Magnetic resonance imaging for characterization of a chick embryo model of cancer cell metastases

Herrmann, A.; Taylor, A.; Murray, P.; Poptani, H.; SEE, V.

10.1101/223891 — cancer biology — Posted on 2017-11-22

452 Regulatory mechanisms are revealed by the distribution of transcription initiation times in single microbial cells

Choubey, S.; Kondev, J.; Sanchez, A.

10.1101/223552 — biophysics — Posted on 2017-11-22

453 Architecture of human interphase chromosome determines the spatiotemporal dynamics of chromatin loci

Liu, L.; Shi, G.; Thirumalai, D.; Hyeon, C.

10.1101/223669 — biophysics — Posted on 2017-11-22

454 IVIM parameters have good scan-rescan reproducibility when evidential motion contaminated and poorly fitted image data are removed

Chevallier, O.; Zhou, N.; He, J.; Loffroy, R.; Wang, Y.-X.

10.1101/179440 — biophysics — Posted on 2017-11-22

455 Authentic Enzyme Intermediates Captured "on-the-fly" by Mix-and-Inject Serial Crystallography

Olmos, J.; Pandey, S.; Martin-Garcia, J. M.; Calvey, G.; Katz, A.; Knoska, J.; Kupitz, C.; Hunter, M. S.; Liang, M.; Oberthuer, D.; Yefanov, O.; Wiedorn, M.; Heymann, M.; Holl, M.; Pande, K.; Barty, A.; Miller, M. D.; Stern, S.; Roy-Chowdhury, S.; Coe, J. D.; Nagaratnam, N.; Zook, J.; Verburgt, J.; Norwood, T.; Poudyal, I.; Xu, D.; Koglin, J.; Seaberg, M.; Zhao, Y.; Bajt, S.; Grant, T.; Mariani, V.; Nelson, G.; Subramanian, G.; Bae, E.; Fromme, R.; Fung, R.; Schwander, P.; Frank, M.; White, T.; Weierstall, U.; Zatsepin, N.; Spence, J.; Fromme, P.; Chapman, H. N.; Pollack, L.; Tremblay, L.; Our

10.1101/202432 — biophysics — Posted on 2017-11-22

456 Efficient Flexible Backbone Protein-Protein Docking for Challenging Targets

Marze, N. A.; Roy Burman, S. S.; Sheffler, W.; Gray, J. J.

10.1101/223511 — biophysics — Posted on 2017-11-22

457 A hidden Markov model approach to characterizing the photo-switching behavior of fluorophores

Patel, L.; Gustafsson, N.; Lin, Y.; Ober, R.; Henriques, R.; Cohen, E.

10.1101/223875 — biophysics — Posted on 2017-11-22

458 Computational haplotype recovery and long-read validation identifies novel isoforms of industrially relevant enzymes from natural microbial communities

Nicholls, S. M.; Aubrey, W.; Edwards, A.; de Grave, K.; Huws, S.; Schietgat, L.; Soares, A.; Creevey, C. J.; Clare, A.

10.1101/223404 — bioinformatics — Posted on 2017-11-22

459 quanTIseq: quantifying immune contexture of human tumors

Finotello, F.; Mayer, C.; Plattner, C.; Laschober, G.; Rieder, D.; Hackl, H.; Krogsdam, A.; Posch, W.; Wilflingseder, D.; Sopper, S.; Jsselsteijn, M.; Johnsons, D.; Xu, Y.; Wang, Y.; Sanders, M. E.; Estrada, M. V.; Ericsson-Gonzalez, P.; Balko, J.; de Miranda, N. F.; Trajanoski, Z.

10.1101/223180 — bioinformatics — Posted on 2017-11-22

460 q2-longitudinal: a QIIME 2 plugin for longitudinal and paired-sample analyses of microbiome data

Bokulich, N.; Zhang, Y.; Dillon, M.; Rideout, J. R.; Bolyen, E.; Li, H.; Albert, P.; Caporaso, J. G.

10.1101/223974 — bioinformatics — Posted on 2017-11-22

461 Prediction of Acute Kidney Injury with a Machine Learning Algorithm using Electronic Health Record Data

Mohamadlou, H.; Lynn-Palevsky, A.; Barton, C.; Chettipally, U.; Shieh, L.; Calvert, J.; Das, R.

10.1101/223354 — bioinformatics — Posted on 2017-11-22

462 Improving Gene Regulatory Network Inference by Incorporating Rates of Transcriptional Change

Desai, J.; Sartor, R. C.; Lawas, L. M.; Jagadish, K. S. V.; Doherty, C. J.

10.1101/093807 — bioinformatics — Posted on 2017-11-22

463 Pediatric Severe Sepsis Prediction Using Machine Learning

Desautels, T.; Hoffman, J.; Barton, C.; Mao, Q.; Jay, M.; Calvert, J.; Das, R.

10.1101/223289 — bioinformatics — Posted on 2017-11-22

464 New synthetic-diploid benchmark for accurate variant calling evaluation

Li, H.; Bloom, J. M.; Farjoun, Y.; Fleharty, M.; Gauthier, L. D.; Neale, B.; MacArthur, D.

10.1101/223297 — bioinformatics — Posted on 2017-11-22

465 Linear models enable powerful differential activity analysis in massively parallel reporter assays

Myint, L.; Avramopoulos, D. G.; Goff, L. A.; Hansen, K. D.

10.1101/196394 — bioinformatics — Posted on 2017-11-22

466 The Oyster River Protocol: A Multi Assembler and Kmer Approach For de novo Transcriptome Assembly

MacManes, M. D.

10.1101/177253 — bioinformatics — Posted on 2017-11-22

467 Modelling the Dynamics of Biological Systems with the Geometric Hidden Markov Model

Vangelov, B.; Barahona, M.

10.1101/224063 — bioinformatics — Posted on 2017-11-22

468 In-solution Y-chromosome capture-enrichment on ancient DNA libraries

Cruz Davalos, D. I.; Nieves-Colon, M. A.; Sockell, A.; Poznik, D. G.; Schroeder, H.; Stone, A. C.; Bustamante, C. D.; Malaspinas, A.-S.; Avila-Arcos, M. C.

10.1101/223214 — genomics — Posted on 2017-11-22

469 deepNF: Deep network fusion for protein function prediction

Gligorijevic, V.; Barot, M.; Bonneau, R.

10.1101/223339 — systems biology — Posted on 2017-11-22

470 Bidirectional Cycling Dynamics of Living Neuronal Networks in Vitro

Gladkov, A.; Grinchuk, O.; Pigareva, Y.; Mukhina, I.; Kazantsev, V.; Pimashkin, A.

10.1101/223230 — neuroscience — Posted on 2017-11-22

471 Prediction of potential disease-associated microRNAs using structural perturbation method

Zeng, X.; Liu, L.; Lu, L.; Zou, Q.

10.1101/223693 — bioinformatics — Posted on 2017-11-22

472 Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule

Tsai, J. C.; Miller-Vedam, L. E.; Anand, A. A.; Jaishankar, P.; Nguyen, H. C.; Renslo, A. R.; Frost, A.; Walter, P.

10.1101/222257 — biochemistry — Posted on 2017-11-22

473 Blind prediction of noncanonical RNA structure at atomic accuracy

Watkins, A. M.; Geniesse, C.; Kladwang, W.; Zakrevsky, P.; Jaeger, L.; Das, R.

10.1101/223305 — biochemistry — Posted on 2017-11-22

474 RetSynth: Solving all optimal retrosynthesis solutions using dynamically constrained integer linear programming

Whitmore, L. S.; Pinar, A.; George, A.; Hudson, C. M.

10.1101/223271 — synthetic biology — Posted on 2017-11-21

475 The ventral stream receives spatial information from the dorsal stream during configural face processing

Zachariou, V.; Mlynaryk, N.; Vernet, M.; Ungerleider, L.

10.1101/222851 — neuroscience — Posted on 2017-11-21

476 Aging and neurodegeneration are associated with increased mutations in single human neurons

Lodato, M. A.; Rodin, R. E.; Bohrson, C. L.; Coulter, M. E.; Barton, A. R.; Kwon, M.; Sherman, M. A.; Vitzhum, C. M.; Luquette, L. J.; Yandava, C.; Yang, P.; Chittenden, T. W.; Hatem, N. E.; Ryu, S. C.; Woodworth, M. B.; Park, P. J.; Walsh, C. A.

10.1101/221960 — genomics — Posted on 2017-11-21

477 Mutations in RPL3L and MYZAP increase risk of atrial fibrillation

Thorolfsdottir, R. B.; Sveinbjornsson, G.; Sulem, P.; Jonsson, S.; Halldorsson, G.; Melsted, P.; Ivarsdottir, E. V.; Davidsson, O. B.; Kristjansson, R. B.; Thorleifsson, G.; Helgadottir, A.; Gretarsdottir, S.; Norddahl, G.; Rajamani, S.; Torfason, B.; Valgardsson, A. S.; Sverrisson, J. T.; Tragante, V.; Asselbergs, F. W.; Roden, D. M.; Darbar, D.; Pedersen, T. R.; Sabatine, M. S.; Lochen, M.-L.; Halldorsson, B. V.; Jonsdottir, I.; Arnar, D. O.; Thorsteinsdottir, U.; Gudbjartsson, D. F.; Holm, H.; Stefansson, K.

10.1101/223578 — genetics — Posted on 2017-11-21

478 Rethinking phylogenetic comparative methods

Uyeda, J. C.; Zenil-Ferguson, R.; Pennell, M. W.

10.1101/222729 — evolutionary biology — Posted on 2017-11-21

479 Live imaging of heart tube development in mouse reveals alternating phases of cardiac differentiation and morphogenesis

Ivanovitch, K.; Temino, S.; Torres, M.

10.1101/170522 — developmental biology — Posted on 2017-11-21

480 Evidence for, and Metabolic Consequences of, a Cardiac Mitochondrial KNa1.2 Channel

Smith, C. O.; Wang, Y. T.; Nadtochiy, S. M.; Miller, J. H.; Jonas, E. A.; Dirksen, R. T.; Nehrke, K.; Brookes, P. S.

10.1101/223321 — cell biology — Posted on 2017-11-21

481 Modular assembly of the nucleolar large subunit processome

Assur Sanghai, Z.; Miller, L.; Molloy, K. R.; Barandun, J.; Hunziker, M.; Chaker-Margot, M.; Wang, J.; Chait, B. T.; Klinge, S.

10.1101/223412 — biochemistry — Posted on 2017-11-21

482 On the proportional abundance of species: Integrating population genetics and community ecology

Marquet, P. A.; Espinoza, G.; Abades, S. R.; Ganz, A.; Rebolledo, R.

10.1101/223529 — ecology — Posted on 2017-11-21

483 Infino: a Bayesian hierarchical model improves estimates of immune infiltration into tumor microenvironment

Zaslavsky, M. E.; Novik, J. B.; Chang, E. J.; Hammerbacher, J. E.

10.1101/221671 — bioinformatics — Posted on 2017-11-21

484 The CURE for Culturing Fastidious Microbes

Bakshi, A.; Webber, A. T.; Patrick, L. E.; Wischusen, E. W.; Thrash, J. C.

10.1101/167130 — scientific communication and education — Posted on 2017-11-21

485 Subtle perturbations of the maize methylome reveal genes and transposons silenced by DNA methylation

Anderson, S. N.; Zynda, G.; Song, J.; Han, Z.; Vaughn, M.; Li, Q.; Springer, N. M.

10.1101/221580 — plant biology — Posted on 2017-11-21

486 k-mer grammar uncovers maize regulatory architecture

Mejia Guerra, M. K.; Buckler, E. S.

10.1101/222927 — plant biology — Posted on 2017-11-21

487 Arabidopsis U1 snRNP subunit LUC7 functions in alternative splicing and preferential removal of terminal introns

de Francisco Amorim, M.; Willing, E.-M.; Droste-Borel, I.; Macek, B.; Schneeberger, K.; Laubinger, S.

10.1101/150805 — plant biology — Posted on 2017-11-21

488 Subtle perturbations of the maize methylome reveal genes and transposons silenced by DNA methylation

Anderson, S. N.; Zynda, G.; Song, J.; Han, Z.; Vaughn, M.; Li, Q.; Springer, N. M.

10.1101/221580 — plant biology — Posted on 2017-11-21

489 Neural circuits for long-range color filling-in

Gerardin, P.; Abbatecola, C.; Devinck, F.; Kennedy, H.; Dojat, M.; Knoblauch, K.

10.1101/223156 — neuroscience — Posted on 2017-11-21

490 A model of multifractality as observed in the neuronal activity of the human basal ganglia

Andres, D.

10.1101/223164 — neuroscience — Posted on 2017-11-21

491 rTMS with individualized resting-state network mapping for neuropsychiatric sequelae of repetitive traumatic brain injury in a retired NFL player

Siddiqi, S. H.; Trapp, N. T.; Hacker, C. D.; Laumann, T. O.; Kandala, S.; Shahim, P.; Carter, A. R.; Brody, D. L.

10.1101/151696 — neuroscience — Posted on 2017-11-21

492 Active sampling state dynamically enhances olfactory bulb odor representation

Jordan, R.; Fukunaga, I.; Kollo, M.; Schaefer, A. T.

10.1101/222588 — neuroscience — Posted on 2017-11-21

493 A Basal Ganglia Circuit Sufficient to Guide Birdsong Learning

Xiao, L.; Chattree, G.; Garcia Oscos, F.; Cao, M.; Wanat, M. J.; Roberts, T. F.

10.1101/222828 — neuroscience — Posted on 2017-11-21

494 The Control of Tonic Pain by Active Relief Learning

Zhang, S.; Mano, H.; Lee, M.; Yoshida, W.; Robbins, T.; Kawato, M.; Seymour, B.

10.1101/222653 — neuroscience — Posted on 2017-11-21

495 A new analysis of resting state connectivity and graph theory reveals distinctive short-term modulations due to whisker stimulation in rats.

Kreitz, S.; de Celis Alonso, B.; Uder, M.; Hess, A.

10.1101/223057 — neuroscience — Posted on 2017-11-21

496 Stochastic satisficing account of confidence in uncertain value-based decisions

Hertz, U.; Bahrami, B.; Keramati, M.

10.1101/107532 — neuroscience — Posted on 2017-11-21

497 Paleo-oscillomics: reconstructing language-relevant computational capacities in Neanderthals from the molecular basis of neural oscillations

Murphy, E.; Benitez-Burraco, A.

10.1101/167528 — neuroscience — Posted on 2017-11-21

498 Decoding of neural data using cohomological learning

Rybakken, E.; Baas, N.; Dunn, B.

10.1101/222331 — neuroscience — Posted on 2017-11-21

499 Using Barcoded Zika Virus to Assess virus Population Structure in vitro and in Aedes aegypti Mosquitoes

Weger-Lucarelli, J.; Garcia, S. M.; Rueckert, C.; Byas, A.; O'Connor, S. L.; Aliota, M. T.; Friedrich, T. C.; O'Connor, D. H.; Ebel, G. D.

10.1101/222984 — molecular biology — Posted on 2017-11-21

500 A Rice Dual-localized Pentatricopeptide Repeat Protein is involved in Organellar RNA Editing with MORFs

Xiao, H.; Xu, Y.; Ni, C.; Zhang, Q.; Zhong, F.; Huang, J.; Zhu, Y.; Hu, J.

10.1101/223115 — molecular biology — Posted on 2017-11-21

501 Inter- and intracellular colonization of Arabidopsis roots by endophytic actinobacteria and the impact of plant hormones on their antimicrobial activity

van der Meij, A.; Willemse, J.; Schneijderberg, M. A.; Geurts, R.; Raaijmakers, J.; van Wezel, G.

10.1101/222844 — microbiology — Posted on 2017-11-21

502 Abundance of Enterovirus C in RD-L20B cell culture negative stool samples from Acute Flaccid Paralysis cases in Nigeria is geographically defined.

Donbraye, E.; Olasunkanmi, O. I.; Opabode, B. A.; Ishola, T. R.; Faleye, T. O. C.; Adewumi, M. O. M.; Adeniji, J. A.

10.1101/222935 — microbiology — Posted on 2017-11-21

503 Predictability and persistence of prebiotic dietary supplementation in a healthy human cohort

Gurry, T.; Microbiome Consortium, H.; Gibbons, S.; Nguyen, L. T. T.; Kearney, S.; Ananthakrishnan, A.; Ziang, X.; Kassam, Z.; Alm, E.

10.1101/222919 — microbiology — Posted on 2017-11-21

504 Translational regulation by bacterial small RNAs via an unusual Hfq-dependent mechanism

Azam, M. S.; Vanderpool, C. K.

10.1101/169359 — microbiology — Posted on 2017-11-21

505 Temperate phages as self-replicating weapons in bacterial competition

Li, X.-Y.; Lachnit, T.; Fraune, S.; Bosch, T. C. G.; Traulsen, A.; Sieber, M.

10.1101/185751 — microbiology — Posted on 2017-11-21

506 Sex differences in the genetic architecture of obsessive-compulsive disorder

Khramtsova, E. A.; Heldman, R.; Derks, E. M.; Yu, D.; TS/OCD Psychiatric Genomics Disorders Workgroup, ; Davis, L. K.; Stranger, B. E.

10.1101/219170 — genomics — Posted on 2017-11-21

507 High Throughput Functional Evaluation of KCNQ1 Decrypts Variants of Unknown Significance

Vanoye, C.; Desai, R.; Fabre, K.; Potet, F.; DeKeyser, J.-M.; Macaya, D.; Meiler, J.; Sanders, C.; George, A.

10.1101/223206 — genetics — Posted on 2017-11-21

508 Proper Conditional Analysis in the Presence of Missing Data Identified Novel Independently Associated Low Frequency Variants in Nicotine Dependence Genes

Jiang, B.; Chen, S.; Jiang, Y.; Liu, M.; Iacono, W. G.; Hewitt, J. K.; Hokanson, J. E.; Krauter, K.; Laakso, M.; Li, K. W.; Lutz, S. M.; McGue, M.; McGuire, D.; Pandit, A.; Zajac, G.; Boehnke, M.; Abecasis, G. R.; Vrieze, S. I.; Zhan, X.; Liu, D. J.

10.1101/222695 — genetics — Posted on 2017-11-21

509 Transcriptomic Imputation of Bipolar Disorder and Bipolar subtypes reveals 29 novel associated genes

Huckins, L.; Dobbyn, A.; McFadden, W.; Wang, W.; Ruderfer, D.; Hoffman, G.; Rajagopal, V.; Nguyen, H. T.; Roussos, P.; Fromer, M.; Kramer, R.; Domenici, E.; Gamazon, E.; CommonMind Consortium, ; Bipolar Disorder Working Group of the Psychiatric, ; iPSYCH Consortium, ; Demontis, D.; Borglum, A.; Devlin, B.; Sieberts, S. K.; Cox, N.; Im, H. K.; Sklar, P.; Stahl, E. A.

10.1101/222786 — genetics — Posted on 2017-11-21

510 Gene expression imputation across multiple brain regions reveals schizophrenia risk throughout development.

Huckins, L. M.; Dobbyn, A.; Ruderfer, D.; Hoffman, G.; Wang, W.; Pardinas, A. F.; Rajagopal, V. M.; Als, T. D.; Hoang, H. T.; Girdhar, K.; Boocock, J.; Roussos, P.; Fromer, M.; Kramer, R.; Domenici, E.; Gamazon, E.; Purcell, S.; CommonMind Consortium, ; Schizophrenia Working Group of the Psychiatric Gen, ; iPSYCH-GEMS Schizophrenia Working Group, ; Demontis, D.; Borglum, A.; Walters, J.; O'Donovan, M.; Sullivan, P. F.; Owen, M.; Devlin, B.; Sieberts, S. K.; Cox, N.; Im, H. K.; Sklar, P.; Stahl, E. A.

10.1101/222596 — genetics — Posted on 2017-11-21

511 Genetic pleiotropy between mood disorders, metabolic, and endocrine traits in a multigenerational pedigree

Kember, R. L.; Hou, L.; Ji, X.; Andersen, L. H.; Ghorai, A.; Estrella, L. N.; Almasy, L.; McMahon, F. J.; Brown, C. D.; Bucan, M.

10.1101/196055 — genetics — Posted on 2017-11-21

512 Experimental assay of a fitness landscape on a macroevolutionary scale

Pokusaeva, V.; Usmanova, D.; Putintseva, E.; Espinar, L.; Sarkisyan, K.; Mishin, A.; Bogatyreva, N.; Ivankov, D.; Filion, G.; Carey, L.; Kondrashov, F. A.

10.1101/222778 — evolutionary biology — Posted on 2017-11-21

513 The predictability of genomic changes underlying a recent host shift in Melissa blue butterflies

Chaturvedi, S.; Lucas, L. K.; Nice, C. C.; Fordyce, J. A.; Forister, M. L.; Gompert, Z.

10.1101/222703 — evolutionary biology — Posted on 2017-11-21

514 Rethinking phylogenetic comparative methods

Uyeda, J. C.; Zenil-Ferguson, R.; Pennell, M. W.

10.1101/222729 — evolutionary biology — Posted on 2017-11-21

515 Fragmentation modes and the evolution of life cycles

Pichugin, Y.; Pena, J.; Rainey, P.; Traulsen, A.

10.1101/120097 — evolutionary biology — Posted on 2017-11-21

516 Reduction in major transcription factor binding domain families during the evolution of the avian lineage

Graham, A. M.; Presnell, J. S.

10.1101/193896 — evolutionary biology — Posted on 2017-11-21

517 Chaos and the (un)predictability of evolution in a changing environment

Rego-Costa, A.; Debarre, F.; Chevin, L.-M.

10.1101/222471 — evolutionary biology — Posted on 2017-11-21

518 A multivariate analysis of CalEnviroScreen: comparing environmental and socioeconomic stressors versus chronic disease

Greenfield, B. K.; Rajan, J.; McKone, T. E.

10.1101/221739 — epidemiology — Posted on 2017-11-21

519 Zoonotic Babesia microti in the northeastern U.S.: evidence for the expansion of a specific parasite lineage

Goethert, H. K.; Molloy, P. J.; Berardi, V.; Weeks, K.; Telford, S.

10.1101/223420 — epidemiology — Posted on 2017-11-21

520 Circulating selenium and prostate cancer risk: a Mendelian randomization analysis

Yarmolinsky, J.; Bonilla, C.; Haycock, P. C.; Langdon, R. J.; Lotta, L. A.; Langenberg, C.; Relton, C. L.; Lewis, S. J.; Evans, D. M.; the PRACTICAL consortium, ; Smith, G. D.; Martin, R. M.

10.1101/223248 — epidemiology — Posted on 2017-11-21

521 Trends in Escherichia coli bloodstream infection, urinary tract infections and antibiotic susceptibilities in Oxfordshire, 1998-2016: an observational study

Vihta, K.-D.; Stoesser, N.; Llewelyn, M. J.; Quan, P. T.; Davies, T.; Fawcett, N.; Dunn, L.; Jeffery, K.; Butler, C.; Hayward, G.; Andersson, M.; Morgan, M.; Oakley, S.; Mason, A.; Wyllie, D. H.; Crook, D.; Wilcox, M.; Johnson, A. P.; Peto, T.; Walker, S. A.

10.1101/223107 — epidemiology — Posted on 2017-11-21

522 Assessing the genetic effect mediated through gene expression from summary eQTL and GWAS data

Barfield, R.; Feng, H.; Gusev, A.; Wu, L.; Zheng, W.; Pasaniuc, B.; Kraft, P.

10.1101/223263 — epidemiology — Posted on 2017-11-21

523 Stability in the genetic structure of a Zymoseptoria tritici population from epidemic to interepidemic stages at a small spatial scale

Morais, D.; Duplaix, C.; Sache, I.; Laval, V.; Suffert, F.; Walker, A.-S.

10.1101/222380 — epidemiology — Posted on 2017-11-21

524 Inference about causation between body mass index and DNA methylation in blood from a twin family study

Li, S.; Wong, E. M.; Bui, M.; Nguyen, T. L.; Joo, J.; Stone, J.; Dite, G. S.; Dugue, P.-A.; Milne, R. L.; Giles, G. G.; Saffery, R.; Southey, M. C.; Hopper, J. L.

10.1101/223040 — epidemiology — Posted on 2017-11-21

525 A structural approach to disentangle the visualization of bipartite biological networks

Garcia-Algarra, J.; Pastor, J. M. M.; Mouronte, M. L.; Galeano, J.

10.1101/192013 — ecology — Posted on 2017-11-21

526 Migration alters oscillatory dynamics and promotes survival in connected bacterial populations

Gokhale, S.; Conwill, A.; Ranjan, T.; Gore, J.

10.1101/223487 — ecology — Posted on 2017-11-21

527 Ca2+-induced mitochondrial ROS regulate the early embryonic cell cycle

Han, Y.; Ishibashi, S.; Iglesias-Gonzalez, J.; Chen, Y.; Love, N. R.; Amaya, E.

10.1101/223123 — developmental biology — Posted on 2017-11-21

528 Elevated and sustained reactive oxygen species levels facilitate mesoderm formation during early Xenopus development

Han, Y.; Chen, Y.; Love, N. R.; Ishibashi, S.; Amaya, E.

10.1101/223453 — developmental biology — Posted on 2017-11-21

529 Effect of vitamin D supplementation on biomarkers of inflammation and immune function: functional genomics analysis of the BEST-D trial

Berlanga-Taylor, A. J.; Plant, K.; Lau, E.; Dahl, A.; Hill, M.; Sims, D.; Heger, A.; Emberson, J.; Armitage, J.; Clarke, R.; Knight, J.

10.1101/217612 — clinical trials — Posted on 2017-11-21

530 The conserved LEM-3/Ankle1 nuclease is involved in the combinatorial regulation of meiotic recombination repair and chromosome segregation in Caenorhabditis elegans

HONG, Y.; Velkova, M.; Silva, N.; Jagut, M.; Scheidt, V.; Labib, K.; Jantsch, V.; Gartner, A.

10.1101/223172 — cell biology — Posted on 2017-11-21

531 Asymmetrical localization of components of the Nup107-160 subcomplex within the nuclear pore complex in fission yeast

Asakawa, H.; Kojidani, T.; Yang, H.-J.; Ohtsuki, C.; Osakada, H.; Iwamoto, M.; Takagi, N.; Nagao, K.; Obuse, C.; Hiraoka, Y.; Haraguchi, T.

10.1101/223131 — cell biology — Posted on 2017-11-21

532 Airway IRF7hi versus IRF7lo molecular response patterns determine clinical phenotypes in children with acute wheezing

Khoo, K.; Read, J.; Franks, K.; Zhang, G.; Bizzintino, J.; Coleman, L.; McCrae, C.; Oberg, L.; Troy, N.; Prastanti, F.; Everard, J.; Oo, S.; Borland, M.; Maciewicz, R.; Le Seouf, P.; Laing, I.; Bosco, A.

10.1101/222950 — cell biology — Posted on 2017-11-21

533 Acute myeloid/T-lymphoblastic leukemia (AMTL): A distinct category of acute leukemias with common pathogenesis in need of improved therapy

Gutierrez, A.; Kentsis, A.

10.1101/223388 — cancer biology — Posted on 2017-11-21

534 Detecting cancer vulnerabilities through gene networks under purifying selection in 4,700 cancer genomes

Gupta, A.; Horn, H.; Razaz, P.; Kim, A.; Lawrence, M.; Getz, G.; Lage, K.

10.1101/222687 — bioinformatics — Posted on 2017-11-21

535 A Web-resource for Nutrient Use Efficiency related Genes, QTLs, and microRNA in important cereals and model plants

Kumar, A.; Pandeya, A.; Malik, G.; P, H. K.; S, A. K.; Sharma, M.; Gahlaut, V.; Gajula, P. M.; Suravajhala, P.; Singh, K. P.; Balyan, H. S.; Gupta, P. K.

10.1101/222992 — bioinformatics — Posted on 2017-11-21

536 DNCON2: Improved protein contact prediction using two-level deep convolutional neural networks

Adhikari, B.; Hou, J.; Cheng, J.

10.1101/222893 — bioinformatics — Posted on 2017-11-21

537 Serum proteins can successfully predict self-reported ethnicity: Implications for precision-medicine

Bishnoi, R.; Palmer, R.; Royall, D. R.

10.1101/221614 — bioinformatics — Posted on 2017-11-21

538 Maize GO Annotation - Methods, Evaluation, and Review (maize-GAMER)

Wimalanathan, K.; Friedberg, I.; Andorf, C. M.; Lawrence-Dill, C. J.

10.1101/222836 — bioinformatics — Posted on 2017-11-21

539 Heritable tumor cell division rate heterogeneity induces clonal dominance

Palm, M. M.; Elemans, M.; Beltman, J. B.

10.1101/097683 — bioinformatics — Posted on 2017-11-21

540 viGEN: An open source pipeline for the detection and quantification of viral RNA in human tumors

Bhuvaneshwar, K.; Song, L.; Madhavan, S.; Gusev, Y.

10.1101/099788 — bioinformatics — Posted on 2017-11-21

541 Detecting cancer vulnerabilities through gene networks under purifying selection in 4,700 cancer genomes

Gupta, A.; Horn, H.; Razaz, P.; Kim, A.; Lawrence, M.; Getz, G.; Lage, K.

10.1101/222687 — bioinformatics — Posted on 2017-11-21

542 K-nearest neighbor smoothing for high-throughput single-cell RNA-Seq data

Wagner, F.; Yan, Y.; Yanai, I.

10.1101/217737 — bioinformatics — Posted on 2017-11-21

543 Computational Design of Asymmetric Three-dimensional RNA Structures and Machines.

Yesselman, J. D.; Eiler, D.; Carlson, E. D.; Ooms, A. N.; Kladwang, W.; Shi, X.; Costantino, D. A.; Herschlag, D.; Jewett, M. C.; Kieft, J. S.; Das, R.

10.1101/223479 — bioengineering — Posted on 2017-11-21

544 Fe2+/H2O2-mediated oxidation of homogentisic acid indicates the production of ochronotic and non-ochronotic pigments. Implications in Alkaptonuria and beyond.

Vercruysse, K.; Taylor, A.; Knight, J.

10.1101/223099 — biochemistry — Posted on 2017-11-21

545 PyFolding: An open-source software package for graphing, simulation and analysis of the biophysical properties of proteins

Lowe, A. R.; Perez-Riba, A.; Itzhaki, L. S.; Main, E.

10.1101/191593 — biochemistry — Posted on 2017-11-21

546 Experimental evidence that female rhesus macaques (Macaca mulatta) perceive variation in male facial masculinity

Rosenfield, K. A.; Semple, S.; Georgiev, A. V.; Maestripieri, D.; HIgham, J. P.; Dubuc, C.

10.1101/222810 — animal behavior and cognition — Posted on 2017-11-21

547 Testing the parasite mass burden effect on host behaviour alteration in the Schistocephalus-stickleback system

Grecias, L.; Valentin, J.; Aubin-Horth, N.

10.1101/222802 — animal behavior and cognition — Posted on 2017-11-21

548 Testing the parasite mass burden effect on host behaviour alteration in the Schistocephalus-stickleback system

Grecias, L.; Valentin, J.; Aubin-Horth, N.

10.1101/222802 — animal behavior and cognition — Posted on 2017-11-21

549 LRX Proteins play a crucial role in pollen grain and pollen tube cell wall development

Ndinyanka Fabrice, T.; Vogler, H.; Draeger, C.; Munglani, G.; Gupta, S.; Herger, A. G.; Knox, P.; Grossniklaus, U.; Ringli, C.

10.1101/223008 — plant biology — Posted on 2017-11-21

550 INSULIN-LIKE PEPTIDES REGULATE FEEDING PREFERENCE AND METABOLISM IN DROSOPHILA

Semanyuk, U.; Gospodaryov, D.; Fedenko, H.; Yurkevych, I.; Vaiserman, A.; Storey, K.; Simpson, S.; Lushchak, O.

10.1101/222539 — physiology — Posted on 2017-11-21

551 Phenotyping ciliary dynamics and coordination in response to CFTR-modulators in Cystic Fibrosis respiratory epithelial cells

Chioccioli, M.; Feriani, L.; Kotar, J.; Bratcher, P. E.; Cicuta, P.

10.1101/223024 — physiology — Posted on 2017-11-21

552 Interplay of target site architecture and miRNA abundance determine miRNA activity and specificity

Brancati, G.; Carl, S. H.; Grosshans, H.

10.1101/214817 — molecular biology — Posted on 2017-11-21

553 Dynamic reorganization of nuclear architecture during human cardiogenesis

Fields, P. A.; Ramani, V.; Bonora, G.; Yardimci, G. G.; Bertero, A.; Reinecke, H.; Pabon, L.; Noble, W. S.; Shendure, J.; Murry, C.

10.1101/222877 — genomics — Posted on 2017-11-21

554 Improved genome assembly and annotation for the rock pigeon (Columba livia)

Holt, C.; Campbell, M.; Keays, D.; Edelman, N.; Kapusta, A.; Maclary, E.; Domyan, E.; Suh, A.; Warrenb, W.; Yandell, M.; Gilbert, T.; Shapiro, M. D.

10.1101/220947 — genomics — Posted on 2017-11-21

555 Integrated analysis of single-cell embryo data yields a unified transcriptome signature for the human preimplantation epiblast

Stirparo, G. G.; Boroviak, T.; Guo, G.; Nichols, J.; Smith, A.; Bertone, P.

10.1101/222760 — developmental biology — Posted on 2017-11-21

556 Allele-specific control of replication timing and genome organization during development

Rivera-Mulia, J. C.; Dimond, A.; Vera, D.; Trevilla-Garcia, C.; Sasaki, T.; Zimmerman, J.; Dupont, C.; Gribnau, J.; Fraser, P.; Gilbert, D. M.

10.1101/221762 — cell biology — Posted on 2017-11-21

557 Cytoplasmic import and processing of mRNA amplify transcriptional bursts accounting for the majority of cellular noise

Hansen, M. M. K.; Desai, R. V.; Simpson, M. L.; Weinberger, L. S.

10.1101/222901 — cell biology — Posted on 2017-11-21

558 Hyperactivation of extracellular signal-regulated kinase (ERK) by RAS-mediated signaling or inhibition of dual specificity phosphatase 6 (DUSP6) is associated with toxicity in lung adenocarcinoma cells with mutations in KRAS or EGFR

Unni, A. M.; Harbourne, B.; Oh, M. H.; Wild, S.; Lockwood, W. W.; Varmus, H.

10.1101/222505 — cancer biology — Posted on 2017-11-21

559 Characterizing Cancer Drug Response andBiological Correlates: A Geometric NetworkApproach

Tannenbaum, A.; Pouryahya, M.; Oh, J. H.; Mathews, J.; Deasy, J.

10.1101/222943 — cancer biology — Posted on 2017-11-21

560 YAMP: a framework enabling reproducibility in metagenomics research

Visconti, A.; Martin, T. C.; Falchi, M.

10.1101/223016 — bioinformatics — Posted on 2017-11-21

561 CREAM: Clustering of genomic REgions Analysis Method

Madani Tonekaboni, S. A.; Mazrooei, P.; Kofia, V.; Haibe-Kains, B.; Lupien, M.

10.1101/222562 — bioinformatics — Posted on 2017-11-21

562 Single-molecule fluorescent amplification of RNA using clampFISH probes

Rouhanifard, S. H.; Dunagin, M.; Mellis, I. A.; Bayatpour, S.; Symmons, O.; Cote, A.; Raj, A.

10.1101/222794 — bioengineering — Posted on 2017-11-21

563 Identification of key pathways and metabolic fingerprints of longevity in C. elegans

Gao, A.; Smith, R.; Van Weeghel, M.; Kamble, R.; Houtkooper, R.

10.1101/222554 — biochemistry — Posted on 2017-11-21

564 Species comparison of liver proteomes reveals enhanced lipid metabolism, reduced mitochondrial respiration and enhanced expression of detoxifying enzymes in the long-lived naked mole-rat.

Heinze, I.; Bens, M.; Calzia, E.; Holtze, S.; Dakhovnik, O.; Sahm, A.; Kirkpatrick, J.; Szafranski, K.; Romanov, N.; Singer, S.; Ermolaeva, M.; Platzer, M.; Hildebrandt, T.; Ori, A.

10.1101/220343 — systems biology — Posted on 2017-11-20

565 The tumor suppressor APC is an attenuator of spindle-pulling forces during C. elegans asymmetric cell division

Sugioka, K.; Fielmich, L.-E.; Mizumoto, K.; Bowerman, B.; van den Heuvel, S.; Kimura, A.; Sawa, H.

10.1101/157404 — cell biology — Posted on 2017-11-20

566 EGLN Inhibition Reduces Gastrointestinal Radiation Toxicity and Improves Survival in a Murine Model of Locally Advanced Pancreatic Cancer

Fujimoto, T. N.; Colbert, L. E.; Molkentine, J. M.; Baseler, L.; Deorukukhar, A.; Kingsley, C. V.; Sawakuchi, G. O.; Tailor, R. C.; Taniguchi, C. M.

10.1101/195610 — cancer biology — Posted on 2017-11-20

567 Peptidomimetic blockade of MYB in acute myeloid leukemia

Ramaswamy, K.; Forbes, L.; Minuesa, G.; Gindin, T.; Brown, F.; Kharas, M.; Krivtsov, A.; Armstrong, S.; Still, E.; de Stanchina, E.; Knoechel, B.; Koche, R.; Kentsis, A.

10.1101/222620 — cancer biology — Posted on 2017-11-20

568 EGLN Inhibition Reduces Gastrointestinal Radiation Toxicity and Improves Survival in a Murine Model of Locally Advanced Pancreatic Cancer

Fujimoto, T. N.; Colbert, L. E.; Molkentine, J. M.; Baseler, L.; Deorukukhar, A.; Kingsley, C. V.; Sawakuchi, G. O.; Tailor, R. C.; Taniguchi, C. M.

10.1101/195610 — cancer biology — Posted on 2017-11-20

569 The magnitude of trial-by-trial neural variability is reproducible over time and across tasks in humans

Arazi, A.; Gonen-Yaacovi, G.; Dinstein, I.

10.1101/096198 — neuroscience — Posted on 2017-11-20

570 Emergence of binocular disparity selectivity through Hebbian learning

Chauhan, T.; Masquelier, T.; Montlibert, A.; Cottereau, B. R.

10.1101/221283 — neuroscience — Posted on 2017-11-20

571 Eye movement-related confounds in neural decoding of visual working memory representations

Mostert, P.; Albers, A. M.; Brinkman, L.; Todorova, L.; Kok, P.; de Lange, F. P.

10.1101/215509 — neuroscience — Posted on 2017-11-20

572 Diurnal changes in glutamate/glutamine levels of healthy young adults assessed by proton magnetic resonance spectroscopy

Volk, C.; Jaramillo, V.; Merki, R. R.; O'Gorman, R. L.; Huber, R.

10.1101/216762 — neuroscience — Posted on 2017-11-20

573 Gene co-expression networks in whole blood implicate multiple interrelated molecular pathways in obese asthma

Croteau-Chonka, D. C.; Chen, Z.; Barnes, K. C.; Barraza-Villarreal, A.; Celedon, J. C.; Gauderman, W. J.; Gilliland, F. D.; Krishnan, J. A.; Liu, A. H.; London, S. J.; Martinez, F. D.; Millstein, J.; Naureckas, E. T.; Nicolae, D. L.; White, S. R.; Ober, C.; Weiss, S. T.; Raby, B. A.

10.1101/181651 — genomics — Posted on 2017-11-20

574 An atlas of Caenorhabditis elegans chemoreceptor expression

Vidal, B.; Aghayeva, U.; Sun, H.; Wang, C.; Glenwinkel, L.; Bayer, E.; Hobert, O.

10.1101/222570 — genetics — Posted on 2017-11-20

575 WeSeqMiner: A Weka package for building machine-learning models for sequence data

Hogan, D.; Maruthachalam, B. V.; Geyer, R. C.; Kusalik, A.

10.1101/217802 — bioinformatics — Posted on 2017-11-20

576 Multi-scale periodicities in the functional brain networks of patients with epilepsy and their effect on seizure detection

Christodoulakis, M.; Anastasiadou, M. N.; Papathanasiou, E. S.; Papacostas, S. S.; Hadjipapas, A.; Mitsis, G. D.

10.1101/221036 — bioengineering — Posted on 2017-11-20

577 A method to keep the excitation light sheet in focus in selective plane illumination microscopy

Gao, L.

10.1101/222497 — bioengineering — Posted on 2017-11-20

578 Hard Limits And Performance Tradeoffs In A Class Of Sequestration Feedback Systems

Olsman, N.; Baetica, A.-A.; Xiao, F.; Leong, Y. P.; Doyle, J.; Murray, R.

10.1101/222042 — systems biology — Posted on 2017-11-20

579 Cell size control driven by the circadian clock and environment in cyanobacteria

Martins, B. M. C.; Tooke, A. K.; Thomas, P.; Locke, J. C. W.

10.1101/183558 — systems biology — Posted on 2017-11-20

580 Strong binding activity of few transcription factors is a major determinant of open chromatin

Wei, B.; Jolma, A.; Sahu, B.; Orre, L. M.; Zhong, F.; Zhu, F.; Kivioja, T.; Sur, I. K.; Lehtio, J.; Taipale, M.; Taipale, J.

10.1101/204743 — systems biology — Posted on 2017-11-20

581 Investigating on relationship between effective quantum efficiency and irradiance

Ye, Z.-P.; Zhou, S.-X.; Yang, X.-L.; Kang, H.-J.; Robakowski, P.

10.1101/222414 — plant biology — Posted on 2017-11-20

582 Decoding of neural data using cohomological learning

Rybakken, E.; Baas, N.; Dunn, B.

10.1101/222331 — neuroscience — Posted on 2017-11-20

583 Sensory attenuation is related to dopamine dose in Parkinson’s disease

Wolpe, N.; Zhang, J.; Nombela, C.; Ingram, J. N.; Wolpert, D. M.; Cam-CAN, ; Rowe, J. B.

10.1101/221317 — neuroscience — Posted on 2017-11-20

584 Age differentiation within grey matter, white matter and between memory and white matter in an adult lifespan cohort

de Mooij, S. M. M.; Henson, R. N. A.; Waldorp, L. J.; Cam-CAN, ; Kievit, R. A.

10.1101/148452 — neuroscience — Posted on 2017-11-20

585 Genetic Single Neuron Anatomy reveals fine granularity of cortical interneuron subtypes

Wang, X.; Tucciarone, J.; Jiang, S.; Yin, F.; Wang, B.-s.; Wang, D.; Jia, Y.; Jia, X.; Li, Y.; Yang, T.; Xu, Z.; Akram, M. A.; Wang, Y.; Zeng, S.; Ascoli, G. A.; Mitra, P.; Gong, H.; Luo, Q.; Huang, Z. J.

10.1101/219485 — neuroscience — Posted on 2017-11-20

586 A perturbation model of the gut microbiome’s response to antibiotics

Shaw, L. P.; Barnes, C. P.; Walker, A. S.; Klein, N.; Balloux, F.

10.1101/222398 — microbiology — Posted on 2017-11-20

587 Recurrently Mutated Genes Differ between Leptomeningeal and Solid Lung Cancer Brain Metastases

Li, Y.; Liu, B.; Connolly, I. D.; Kakusa, B. W.; Pan, W.; Nagpal, S.; Montgomery, S. B.; Gephart, M. H.

10.1101/222349 — genomics — Posted on 2017-11-20

588 Meiotic Crossover Patterning In The Absence Of ATR: Loss Of Interference And Assurance But Not The Centromere Effect

Brady, M. M.; McMahan, S.; Sekelsky, J.

10.1101/143651 — genetics — Posted on 2017-11-20

589 Patterns of Z chromosome divergence among Heliconius species highlight the importance of historical demography

Van Belleghem, S. M.; Baquero, M.; Papa, R.; Salazar, C.; McMillan, W. O.; Counterman, B. A.; Jiggins, C. D.; Martin, S. H.

10.1101/222430 — evolutionary biology — Posted on 2017-11-20

590 Chaos and the (un)predictability of evolution in a changing environment

Rego-Costa, A.; Debarre, F.; Chevin, L.-M.

10.1101/222471 — evolutionary biology — Posted on 2017-11-20

591 Bacterial adaptation to host diet is a key evolutionary force shaping host-microbe symbiosis

Martino, M. E.; Joncour, P.; Leenay, R.; Gervais, H.; Shaw, M.; Hughes, S.; Gillet, B.; Beisel, C.; Leulier, F.

10.1101/222364 — evolutionary biology — Posted on 2017-11-20

592 Higher eukaryote-specific APC/C composition is a determinant of spindle assembly checkpoint importance

Wild, T.; Budzowska, M.; Karemore, G.; Choudhary, C.

10.1101/222422 — cell biology — Posted on 2017-11-20

593 A Biomaterial Screening Approach to Reveal Microenvironmental Mechanisms of Drug Resistance

Schwartz, A. D.; Barney, L. E.; Jansen, L. E.; Nguyen, T. V.; Hall, C. L.; Meyer, A. S.; Peyton, S.

10.1101/168039 — bioengineering — Posted on 2017-11-20

594 Attomol-level quantification of chemically modified ribonucleosides enabled by capillary porous graphitic carbon columns in nano LC-MS

Sarin, P.; Kienast, S. D.; Leufken, J.; Ross, R. R.; Limbach, P. A.; Fufezan, C.; Drexler, H. C. A.; Leidel, S.

10.1101/222315 — biochemistry — Posted on 2017-11-20

595 Naked mole-rat transcriptome signatures of socially-suppressed sexual maturation and links of reproduction to aging

Bens, M.; Szafranski, K.; Holtze, S.; Sahm, A.; Groth, M.; Kestler, H. A.; Hildebrandt, T. B.; Platzer, M.

10.1101/221333 — systems biology — Posted on 2017-11-20

596 Knockdown of Liver-Derived C1 Inhibitor Results in Brain Pathology in mice

Farfara, D.; Feierman, E.; Richards, A.; Revenko, A. S.; MacLeod, R. A.; Norris, E. H.; Strickland, S.

10.1101/216531 — neuroscience — Posted on 2017-11-20

597 Tracking wakefulness as it fades: micro-measures of Alertness

Jagannathan, S. R.; Nassar, A. E.; Jachs, B.; Pustovaya, O. V.; Bareham, C. A.; Bekinschtein, T. A.

10.1101/219527 — neuroscience — Posted on 2017-11-20

598 Fronto-limbic dysconnectivity leads to impaired brain network controllability in young people with bipolar disorder and those at high genetic risk

Jeganathan, J.; Perry, A.; Bassett, D. S.; Roberts, G.; Mitchell, P. B.; Breakspear, M.

10.1101/222216 — neuroscience — Posted on 2017-11-20

599 Performance-optimized hierarchical models only partially predict neural responses during perceptual decision making

Gwilliams, L.; King, J.-R.

10.1101/221630 — neuroscience — Posted on 2017-11-20

600 Rapid high-resolution measurement of DNA replication timing by droplet digital PCR

Batrakou, D. G.; Heron, E. D.; Nieduszynski, C. A.

10.1101/208546 — molecular biology — Posted on 2017-11-20

601 Within host selection for faster replicating bacterial symbionts

Chrostek, E.; Teixeira, L.

10.1101/222240 — microbiology — Posted on 2017-11-20

602 Comparison of whole-genome bisulfite sequencing library preparation strategies identifies sources of biases affecting DNA methylation data

Olova, N.; Krueger, F.; Andrews, S.; Oxley, D.; Berrens, R. V.; Branco, M. R.; Reik, W.

10.1101/165449 — genomics — Posted on 2017-11-20

603 iterative Random Forests to discover predictive and stable high order interactions

Basu, S.; Kumbier, K.; Brown, J. B.; Yu, B.

10.1101/222299 — genomics — Posted on 2017-11-20

604 Molecular basis of hemoglobin adaptation in the high-flying bar-headed goose

Storz, J. F.; Natarajan, C.; Jendroszek, A.; Kumar, A.; Weber, R. E.; Tame, J. R.; Fago, A.

10.1101/222182 — genomics — Posted on 2017-11-20

605 Dynamics of the upper airway microbiome in the pathogenesis of asthma-associated persistent wheeze in preschool children

Teo, S. M.; Tang, H. H.; Mok, D.; Judd, L. M.; Watts, S. C.; Pham, K.; Holt, B. J.; Kusel, M.; Serralha, M.; Troy, N.; Bochkov, Y. A.; Grindle, K.; Lemanske, R. F.; Johnston, S. L.; Gern, J. E.; Sly, P. D.; Holt, P. G.; Holt, K. E.; Inouye, M.

10.1101/222190 — genetics — Posted on 2017-11-20

606 Leveraging polygenic functional enrichment to improve GWAS power

Kichaev, G.; Bhatia, G.; Loh, P.-R.; Gazal, S.; Burch, K.; Freund, M.; Scoech, A.; Pasaniuc, B.; Price, A.

10.1101/222265 — genetics — Posted on 2017-11-20

607 Beyond Brownian motion and the Ornstein-Uhlenbeck process: Stochastic diffusion models for the evolution of quantitative characters.

Blomberg, S. P.

10.1101/067363 — evolutionary biology — Posted on 2017-11-20

608 Deciphering the histone code to build the genome structure

Prakash, K.; Fournier, D.

10.1101/217190 — cell biology — Posted on 2017-11-20

609 Shaping Epigenetic Memory via Genomic Bookmarking

Michieletto, D.; Chiang, M.; Coli, D.; Papantonis, A.; Orlandini, E.; Cook, P. R.; Marenduzzo, D.

10.1101/184598 — biophysics — Posted on 2017-11-20

610 Denaturants alter the flux through multiple pathways in the folding of PDZ domain

Liu, Z.; Thirumalai, D.

10.1101/221945 — biophysics — Posted on 2017-11-20

611 cycleX: multi-dimensional pseudotime reveals cell cycle and differentiation relationship of dendritic cell progenitors

Tan, Y. K.; Zhang, X.; Chen, J.

10.1101/222372 — bioinformatics — Posted on 2017-11-20

612 Recurrent Neural Networks with Interpretable Cells Predict and Classify Worm Behaviour

Li, K.; Javer, A.; Keaveny, E. E.; Brown, A. E. X.

10.1101/222208 — animal behavior and cognition — Posted on 2017-11-20

613 Glutamatergic drive along the septo-temporal axis of hippocampus boosts prelimbic oscillations in the neonatal mouse

Ahlbeck, J.; Song, L.; Chini, M.; Candela, A.; Bitzenhofer, S. H.; Hanganu-Opatz, I. L.

10.1101/222166 — neuroscience — Posted on 2017-11-19

614 Chasing a moving target: Detection of mitochondrial heteroplasmy for clinical diagnostics

White, E. J.; Ross, T.; Lopez, E.; Nikiforov, A.; Gault, C.; Batorsky, R.; Darcy, C.; Campagna, D.; Fleming, M.; Thompson, J.

10.1101/222109 — genomics — Posted on 2017-11-19

615 Dietary and behavioral inferences from dental pathology and non-masticatory wear on dentitions from a British medieval town

Towle, I.; Davenport, C.; Irish, J.; De Groote, I.

10.1101/222091 — pathology — Posted on 2017-11-19

616 Root grooves on two adjacent anterior teeth of Australopithecus africanus

Towle, I.; Irish, J.; Elliott, M.; De Groote, I.

10.1101/222059 — paleontology — Posted on 2017-11-19

617 Superficial Slow Rhythms Integrate Cortical Processing in Humans

Halgren, M.; Fabo, D.; Ulbert, I.; Madsen, J. R.; Eross, L.; Doyle, W. K.; Devinsky, O.; Schomer, D.; Cash, S. S.; Halgren, E.

10.1101/202549 — neuroscience — Posted on 2017-11-19

618 A comparison of tests for quantifying sensory eye dominance

Bossi, M.; Hamm, L.; Dahlmann-Noor, A.; Dakin, S.

10.1101/219816 — neuroscience — Posted on 2017-11-19

619 Recording neural activity in unrestrained animals with 3D tracking two photon microscopy

Karagyozov, D.; Mihovilovic Skanata, M.; Lesar, A.; Gershow, M.

10.1101/213942 — neuroscience — Posted on 2017-11-19

620 Hyperedge bundling: A practical solution to spurious interactions in MEG/EEG source connectivity analyses

Wang, S. H.; Lobier, M.; Siebenhuhner, F.; Puolivali, T.; Palva, S.; Palva, J. M.

10.1101/219311 — neuroscience — Posted on 2017-11-19

621 Bayesian adaptive stimulus selection for dissociating models of psychophysical data

Cooke, J. R. H.; Selen, L. P. J.; van Beers, R. J.; Medendorp, W. P.

10.1101/220590 — neuroscience — Posted on 2017-11-19

622 Bayesian adaptive stimulus selection for dissociating models of psychophysical data

Cooke, J. R. H.; Selen, L. P. J.; van Beers, R. J.; Medendorp, W. P.

10.1101/220590 — neuroscience — Posted on 2017-11-17

623 Methylation guide RNA evolution in archaea: structure, function, and genomic organization of 110 C/D box sRNA families across six Pyrobaculum species

Lui, L. M.; Uzilov, A. V.; Bernick, D. L.; Corredor, A.; Lowe, T. M.; Dennis, P. P.

10.1101/121921 — molecular biology — Posted on 2017-11-19

624 Permissive zones for the centromere-binding protein ParB on the Caulobacter crescentus chromosome

Tran, N. T.; Stevenson, C. E.; Som, N. F.; Thanapipatsiri, A.; Jalal, A. S. B.; Le, T. B. K.

10.1101/172932 — microbiology — Posted on 2017-11-19

625 Determinants of target prioritization and regulatory hierarchy for the bacterial small RNA SgrS

Bobrovskyy, M.; Frandsen, J.; Zhang, J.; Poddar, A.; Azam, M. S.; Henkin, T. M.; Ha, T.; Vanderpool, C. K.

10.1101/221978 — microbiology — Posted on 2017-11-19

626 Genomic features and evolution of the conditionally dispensable chromosome in the tangerine pathotype of Alternaria alternata

Wang, M.; Fu, H.; Shen, X.-X.; Ruan, R.; Pun, N.; Xu, J.; Li, H.; Rokas, A.

10.1101/207746 — microbiology — Posted on 2017-11-19

627 Detection Of Cooperatively Bound Transcription Factor Pairs Using ChIP-seq Peak Intensities And Expectation Maximization

Datta, V.; Siddharthan, R.; Krishna, S.

10.1101/120113 — genomics — Posted on 2017-11-19

628 Insights into platypus population structure and history from whole-genome sequencing

Martin, H. C.; Batty, E. M.; Hussin, J.; Westall, P.; Daish, T.; Kolomyjec, S.; Piazza, P.; Bowden, R.; Hawkins, M.; Grant, T.; Moritz, C.; Grutzner, F.; Gongora, J.; Donnelly, P.

10.1101/221481 — genomics — Posted on 2017-11-19

629 Adaptive significance of frontal eyes: Binocular disparity improves the capacity of vision

Railo, H.; Saastamoinen, J.; Kylmala, S.; Peltola, A.

10.1101/222034 — evolutionary biology — Posted on 2017-11-19

630 Selection for pollen competitive ability in mixed mating systems

Peters, M. A. E.; Weis, A. E.

10.1101/222117 — evolutionary biology — Posted on 2017-11-19

631 Symmetric assembly and disassembly processes in an ecological network

Tylianakis, J.; Martinez-Garcia, L.; Richardson, S.; Peltzer, D.; Dickie, I. A.

10.1101/042572 — ecology — Posted on 2017-11-19

632 On Model Averaging Partial Regression Coefficients

Walker, J. A.

10.1101/133785 — ecology — Posted on 2017-11-19

633 Selective Filopodia Adhesion Ensures Robust Cell Matching in the Drosophila Heart

Zhang, S.; Amourda, C.; Saunders, T.

10.1101/222018 — developmental biology — Posted on 2017-11-19

634 Topography and refractometry of sperm cells using SLIM

Liu, L.; Kandel, M. E.; Rubessa, M.; Schreiber, S.; Wheeler, M.; Popescu, G.

10.1101/222000 — cell biology — Posted on 2017-11-19

635 Prevention and reversion of pancreatic tumorigenesis through a differentiation-based mechanism

Krah, N. M.; Yugawa, D.; Straley, J.; Wright, C. V. E.; MacDonald, R. J.; Murtaugh, L. C.

10.1101/221986 — cancer biology — Posted on 2017-11-19

636 Euplotid: A quantized geometric model of life

Borges-Rivera, D.

10.1101/170159 — biophysics — Posted on 2017-11-19

637 Length and time scales of cell-cell signaling circuits in agar

Doong, J.; Parkin, J.; Murray, R. M.

10.1101/220244 — synthetic biology — Posted on 2017-11-18

638 Expansion and diversification of the gibberellin receptor GIBBERELLIN INSENSITIVE DWARF1 (GID1) in land plants

Gazara, R. K.; Moharana, K. C.; Bellieny-Rabelo, D.; Venancio, T. M.

10.1101/221937 — plant biology — Posted on 2017-11-18

639 Transcriptional control and exploitation of an immune-responsive family of retrotransposons in Arabidopsis

Deleris, A.; Zervudacki, J.; Yu, A.; Wang, J.; Drouaud, J.; Navarro, L.

10.1101/206813 — plant biology — Posted on 2017-11-18

640 Human-specific NOTCH-like genes in a region linked to neurodevelopmental disorders affect cortical neurogenesis

Fiddes, I. T.; Lodewijk, G. A.; Mooring, M. M.; Bosworth, C. M.; Ewing, A. D.; Mantalas, G. L.; Novak, A. M.; van den Bout, A.; Bishara, A.; Rosenkrantz, J. L.; Lorig-Roach, R.; Field, A. R.; Haeussler, M.; Russo, L.; Bhaduri, A.; Nowakowski, T. J.; Pollen, A. A.; Dougherth, M. L.; Nuttle, X.; Addor, M.-C.; Zwolinski, S.; Katzman, S.; Kreigstein, A.; Eichler, E. E.; Salama, S. R.; Jacobs, F. M.; Haussler, D.

10.1101/221226 — neuroscience — Posted on 2017-11-18

641 The Generation and Propagation of the Human Alpha Rhythm

Halgren, M.; Devinsky, O.; Doyle, W. K.; Bastuji, H.; Rey, M.; Mak-McCully, R.; Chauvel, P.; Ulbert, I.; Fabo, D.; Wittner, L.; Heit, G.; Eskandar, E.; Mandell, A.; Cash, S. S.

10.1101/202564 — neuroscience — Posted on 2017-11-18

642 Biologically plausible mechanisms underlying motor response correction during reward-based decision-making

Lee, J. H.

10.1101/221770 — neuroscience — Posted on 2017-11-18

643 Transcription activator-coactivator specificity is mediated by a large and dynamic fuzzy protein-protein complex

Tuttle, L. M.; Pacheco, D.; Warfield, L.; Luo, J.; Ranish, J.; Hahn, S.; Klevit, R. E.

10.1101/221747 — molecular biology — Posted on 2017-11-18

644 Time intervals in sequence sampling, not data modifications, have a major impact on estimates of HIV escape rates

Ganusov, V. V.

10.1101/221812 — immunology — Posted on 2017-11-18

645 Defining kinetic properties of HIV-specific CD8+ T-cell responses in acute infection

Yang, Y.; Ganusov, V. V.

10.1101/158683 — immunology — Posted on 2017-11-18

646 Higher-order inter-chromosomal hubs shape 3-dimensional genome organization in the nucleus

Quinodoz, S. A.; Ollikainen, N.; Tabak, B.; Palla, A.; Schmidt, J. M.; Detmar, E.; Lai, M.; Shishkin, A.; Bhat, P.; Trinh, V.; Aznauryan, E.; Russell, P.; Cheng, C.; Jovanovic, M.; Chow, A.; McDonel, P.; Garber, M.; Guttman, M.

10.1101/219683 — genomics — Posted on 2017-11-18

647 Insights into platypus population structure and history from whole-genome sequencing

Martin, H. C.; Batty, E. M.; Hussin, J.; Westall, P.; Daish, T.; Kolomyjec, S.; Piazza, P.; Bowden, R.; Hawkins, M.; Grant, T.; Moritz, C.; Grutzner, F.; Gongora, J.; Donnelly, P.

10.1101/221481 — genomics — Posted on 2017-11-18

648 Transcription start site analysis reveals widespread divergent transcription in D. melanogaster and core promoter encoded enhancer activities

Rennie, S.; Dalby, M.; Lloret-Llinares, M.; Bakoulis, S.; Dalager Vaagenso, C.; Jensen, T. H.; Andersson, R.

10.1101/221952 — genomics — Posted on 2017-11-18

649 Genome-wide identification of directed gene networks using large-scale population genomics data

Luijk, R.; Dekkers, K. F.; van Iterson, M.; Arindrarto, W.; Claringbould, A.; Hop, P.; BIOS Consortium, ; Boomsma, D. I.; van Duin, C. M.; Veldink, J. H.; van Greevenbroek, M. M.; Wijmenga, C.; Franke, L.; 't Hoen, P. A.; Jansen, R.; van Meurs, J.; Mei, H.; Slagboom, E. P.; Heijmans, B. T.; van Zwet, E. W.

10.1101/221879 — genomics — Posted on 2017-11-18

650 Standardizing microsatellite panels for individual identification of seabirds’ Snow Petrel Pagodroma nivea and Wilson’s Storm Petrel Oceanites oceanicus in Antarctica

Pande, A.; Rawat, N.; Sivakumar, K.; Sathyakumar, S.; Mathur, V. B.; Mondol, S.

10.1101/221861 — genetics — Posted on 2017-11-18

651 Causal gene inference by multivariate mediation analysis in Alzheimer’s disease

Park, Y.; Sarkar, A.; He, L.; Davila-Velderrain, J.; De Jager, P. L.; Kellis, M.

10.1101/219428 — genetics — Posted on 2017-11-18

652 Population dynamics of mutualism and intraspecific density dependence: how θ-logistic density dependence affects mutualistic positive feedback

Moore, C. M.; Catella, S. A.; Abbott, K. C.

10.1101/108175 — ecology — Posted on 2017-11-18

653 Identification and characterisation of the cryptic Golgi Apparatus in Naegleria gruberi

Herman, E.; Yiangou, L.; Cantoni, D. M.; Miller, C.; Marciano-Cabral, F.; Anthonyrajah, E.; Dacks, J.; Tsaousis, A.

10.1101/221721 — cell biology — Posted on 2017-11-18

654 Coarse-grained simulations of actomyosin rings point to a nodeless model involving both unipolar and bipolar myosins

Nguyen, L.; Swulius, M. T.; Aich, S.; Mishra, M.; Jensen, G. J.

10.1101/194910 — biophysics — Posted on 2017-11-18

655 Denaturants alter the flux through multiple pathways in the folding of PDZ domain

Liu, Z.; Thirumalai, D.

10.1101/221945 — biophysics — Posted on 2017-11-18

656 Wx: a neural network-based feature selection algorithm for next-generation sequencing data

Park, S.; Shin, B.; Choi, Y.; Kang, K.; Kang, K.

10.1101/221911 — bioinformatics — Posted on 2017-11-18

657 Targeted Genotyping of Variable Number Tandem Repeats with adVNTR

Bakhtiari, M.; Shleizer-Burko, S.; Gymrek, M.; Bansal, V.; Bafna, V.

10.1101/221754 — bioinformatics — Posted on 2017-11-18

658 Transgenic mouse lines expressing the 3xFLAG-dCas9 protein for enChIP analysis

Fujita, T.; Kitaura, F.; Oji, A.; Tanigawa, N.; Yuno, M.; Ikawa, M.; Taniuchi, I.; Fujii, H.

10.1101/221820 — biochemistry — Posted on 2017-11-18

659 Human-specific NOTCH-like genes in a region linked to neurodevelopmental disorders affect cortical neurogenesis

10.1101/221226 — neuroscience — Posted on 2017-11-17

660 Human-specific NOTCH-like genes in a region linked to neurodevelopmental disorders affect cortical neurogenesis

10.1101/221226 — neuroscience — Posted on 2017-11-17

661 Walking behavior in a circular arena modified by pulsed light stimulation in Drosophila melanogaster w1118 line

Qiu, S.; Xiao, C.

10.1101/119966 — animal behavior and cognition — Posted on 2017-11-17

662 Strong binding activity of few transcription factors is a major determinant of open chromatin

Wei, B.; Jolma, A.; Sahu, B.; Orre, L. M.; Zhong, F.; Zhu, F.; Kivioja, T.; Sur, I. K.; Lehtio, J.; Taipale, M.; Taipale, J.

10.1101/204743 — systems biology — Posted on 2017-11-17

663 Species comparison of liver proteomes reveals enhanced lipid metabolism, reduced mitochondrial respiration and enhanced expression of detoxifying enzymes in the long-lived naked mole-rat.

Heinze, I.; Bens, M.; Calzia, E.; Holtze, S.; Dakhovnik, O.; Sahm, A.; Kirkpatrick, J.; Szafranski, K.; Romanov, N.; Singer, S.; Ermolaeva, M.; Platzer, M.; Hildebrandt, T.; Ori, A.

10.1101/220343 — systems biology — Posted on 2017-11-17

664 Integrating co-expression networks with GWAS detects genes driving elemental accumulation in maize seeds

Schaefer, R. J.; Michno, J.-M.; Jeffers, J.; Hoekenga, O.; Dilkes, B.; Baxter, I.; Myers, C.

10.1101/221655 — systems biology — Posted on 2017-11-17

665 Tn-Core: context-specific reconstruction of core metabolic models using Tn-seq data

diCenzo, G.; Mengondi, A.; Fondi, M.

10.1101/221325 — systems biology — Posted on 2017-11-17

666 A neuronal theory of sequential economic choice

Hayden, B.; Moreno-Bote, R.

10.1101/221135 — neuroscience — Posted on 2017-11-17

667 Self-organised attractor dynamics in the developing head direction circuit.

Bassett, J. P.; Cacucci, F.; Wills, T. J.

10.1101/221028 — neuroscience — Posted on 2017-11-17

668 LRRTM1 underlies synaptic convergence in visual thalamus

Monavarfeshani, A.; Stanton, G.; Van Name, J.; Su, K.; Mills, W.; Swilling, K.; Kerr, A.; Su, J.; Fox, M. A.

10.1101/221200 — neuroscience — Posted on 2017-11-17

669 Motor selection dynamics in FEF explain the reaction time variance of saccades to single targets

Hauser, C. K.; Zhu, D.; Stanford, T. R.; Salinas, E.

10.1101/221218 — neuroscience — Posted on 2017-11-17

670 Replay of large-scale spatio-temporal patterns from waking during subsequent slow-wave sleep in human cortex

Jiang, X.; Shamie, I.; Doyle, W.; Friedman, D.; Dugan, P.; Devinsky, O.; Eskandar, E.; Cash, S. S.; Thesen, T.; Halgren, E.

10.1101/221275 — neuroscience — Posted on 2017-11-17

671 Selective attention modulates surface filling-in

Harrison, W. J.; Ayeni, A. J.; Bex, P. J.

10.1101/221150 — neuroscience — Posted on 2017-11-17

672 Oxidative stress and loss of Fe-S proteins in Friedreich ataxia induced pluripotent stem cell-derived PSNs can be reversed by restoring FXN expression with a benzamide HDAC inhibitor.

Hu, A.; Rai, M.; Donatello, S.; Pandolfo, M.

10.1101/221242 — neuroscience — Posted on 2017-11-17

673 Reconstruction of resting-state networks from macaqueelectrocorticographic data

Hindriks, R.; Micheli, C.; Bosman, C.; Oostenveld, R.; Lewis, C. M.; Mantini, D.; Fries, P.; Deco, G.

10.1101/221051 — neuroscience — Posted on 2017-11-17

674 A Multilevel Computational Characterization of Endophenotypes in Addiction

Fiore, V. G.; Ognibene, D.; Adinoff, B.; Gu, X.

10.1101/220905 — neuroscience — Posted on 2017-11-17

675 Spontaneous eye blink rate and dopamine synthesis capacity: Preliminary evidence for an absence of positive correlation

Sescousse, G.; Ligneul, R.; van Holst, R. J.; Janssen, L. K.; de Boer, F.; Janssen, M.; Berry, A. S.; Jagust, W. J.; Cools, R.

10.1101/215178 — neuroscience — Posted on 2017-11-17

676 Temporal epigenomic profiling identifies AHR as dynamic super-enhancer controlled regulator of mesenchymal multipotency

Gerard, D.; Schmidt, F.; Ginolhac, A.; Schmitz, M.; Halder, R.; Ebert, P.; Schulz, M. H.; Sauter, T.; Sinkkonen, L.

10.1101/183988 — molecular biology — Posted on 2017-11-17

677 Giant flagellins form thick flagellar filaments in two species of marine Gammaproteobacteria

Thomson, N. M.; Ferreira, J. L.; Matthews-Palmer, T. R.; Beeby, M.; Pallen, M. J.

10.1101/221366 — microbiology — Posted on 2017-11-17

678 Viral hijacking of the nucleolar DNA-damage response machinery: a novel mechanism to regulate host cell biology

Rawlinson, S. M.; Zhao, T.; Rozario, A. M.; Rootes, C. L.; McMillan, P. J.; Purcell, A. W.; Woon, A.; Marsh, G. A.; Lieu, K. G.; Wang, L.-F.; Netter, H. J.; Bell, T. D.; Stewart, C. R.; Moseley, G. W.

10.1101/219071 — microbiology — Posted on 2017-11-17

679 Molecularly barcoded Zika virus libraries to probe in vivo evolutionary dynamics

Aliota, M. T.; Dudley, D. M.; Newman, C. M.; Weger-Lucarelli, J.; Stewart, L. M.; Koenig, M. R.; Breitbach, M. E.; Weiler, A. M.; Semler, M. R.; Barry, G. L.; Zarbock, K. R.; Mohns, M. S.; Mohr, E. L.; Venturi, V.; Schultz-Darken, N.; Peterson, E.; Newton, W.; Schotzko, M. L.; Simmons, H. A.; Mejia, A.; Hayes, J. M.; Capuano, S.; Davenport, M. P.; Friedrich, T. C.; Ebel, G. D.; O'Connor, S. L.; O'Connor, D. H.

10.1101/221564 — microbiology — Posted on 2017-11-17

680 Estimating the effects of variation in viremia on mosquito susceptibility, infectiousness, and R0 of Zika in Aedes aegypti

Tesla, B.; Demakovsky, L. R.; Packiam, H. S.; Mordecai, E. A.; Rodriguez, A. D.; Bonds, M. H.; Brindley, M. A.; Murdock, C. C.

10.1101/221572 — microbiology — Posted on 2017-11-17

681 Application of the immunoregulatory receptor LILRB1 as a novel crystallisation chaperone for class I peptide-MHC complexes

Mohammed, F.; Stones, D.; Willcox, B. E.

10.1101/213207 — immunology — Posted on 2017-11-17

682 HIV-1 unmasks the plasticity of innate lymphoid cells

Wang, Y.; Gellatly, K.; Derr, A.; Jaiswal, S.; Kucukural, A.; McDonel, P.; Greenough, T.; Houghton, J.; Garber, M.; Luban, J.

10.1101/221010 — immunology — Posted on 2017-11-17

683 A de novo approach to disentangle partner identity and function in holobiont systems

Meng, A.; Marchet, C.; Corre, E.; Peterlongo, P.; Alberti, A.; Da Silva, C.; Wincker, P.; Pelletier, E.; Probert, I.; Decelle, J.; Le Crom, S.; Not, F.; Bittner, L.

10.1101/221424 — genomics — Posted on 2017-11-17

684 Insights into platypus population structure and history from whole-genome sequencing

Martin, H. C.; Batty, E. M.; Hussin, J.; Westall, P.; Daish, T.; Kolomyjec, S.; Piazza, P.; Bowden, R.; Hawkins, M.; Grant, T.; Moritz, C.; Grutzner, F.; Gongora, J.; Donnelly, P.

10.1101/221481 — genomics — Posted on 2017-11-17

685 The association between the HLA-DRB1 shared epitope alleles and the risk of rheumatoid arthritis is influenced by massive gene-gene interactions.

Diaz-Gallo, L. M.; Ramsköld, D.; Shchetynsky, K.; Folkersen, L.; Chemin, K.; Brynedal, B.; Uebe, S.; Okada, Y.; Alfredsson, L.; Klareskog, L.; Padyukov, L.

10.1101/221416 — genetics — Posted on 2017-11-17

686 Effects of partial selfing on the equilibrium genetic variance, mutation load and inbreeding depression under stabilizing selection

Abu Awad, D.; Roze, D.

10.1101/180000 — evolutionary biology — Posted on 2017-11-17

687 PHYLOSCANNER: Inferring Transmission from Within- and Between-Host Pathogen Genetic Diversity

Wymant, C.; Hall, M.; Ratmann, O.; Bonsall, D.; Golubchik, T.; de Cesare, M.; Gall, A.; Cornelissen, M.; Fraser, C.; STOP-HCV Consortium, ; The Maela Pneumococcal Collaboration, ; The BEEHIVE Collaboration,

10.1101/157768 — evolutionary biology — Posted on 2017-11-17

688 Don’t throw out the sympatric species with the crater lake water: fine-scale investigation of introgression provides weak support for functional role of secondary gene flow in one of the clearest examples of sympatric speciation

Richards, E.; Poelstra, J.; Martin, C.

10.1101/217984 — evolutionary biology — Posted on 2017-11-17

689 The evolution of social life in family groups

Kramer, J.; Meunier, J.

10.1101/221192 — evolutionary biology — Posted on 2017-11-17

690 Gene buddies: Linked balanced polymorphisms reinforce each other even in the absence of epistasis

Tennessen, J. A.

10.1101/220897 — evolutionary biology — Posted on 2017-11-17

691 The polygenic basis of an ancient divergence in yeast thermotolerance

Weiss, C.; Roop, J. I.; Hackley, R.; Chuong, J.; Grigoriev, I. V.; Arkin, A. P.; Skerker, J. M.; Brem, R. B.

10.1101/220913 — evolutionary biology — Posted on 2017-11-17

692 A simple rule for the evolution of fast dispersal at the edge of expanding populations

Deforet, M.; Carmona-Fontaine, C.; Korolev, K. S.; Xavier, J. B.

10.1101/221390 — evolutionary biology — Posted on 2017-11-17

693 Deleterious variation mimics signatures of genomic incompatibility and adaptive introgression

Kim, B. Y.; Huber, C. D.; Lohmueller, K.

10.1101/221705 — evolutionary biology — Posted on 2017-11-17

694 Assessing the stability of polio eradication after the withdrawal of oral polio vaccine

Famulare, M.; Selinger, C.; McCarthy, K. A.; Eckhoff, P. A.; Chabot-Couture, G.

10.1101/084012 — epidemiology — Posted on 2017-11-17

695 The relationship between varicella (chickenpox) and scarlet fever in contemporary Hong Kong

Coleman, S.

10.1101/221507 — epidemiology — Posted on 2017-11-17

696 Regime shifts and hysteresis in the Sarracenia microecosystem

Lau, M. K.; Baiser, B.; Northrop, A.; Gotelli, N. J.; Ellison, A. M.

10.1101/087296 — ecology — Posted on 2017-11-17

697 GMSE: an R package for generalised management strategy evaluation

Duthie, A. B.; Cusack, J. J.; Jones, I. L.; Nilsen, E. B.; Pozo, R. A.; Rakotonarivo, O. S.; Van Moorter, B.; Bunnefeld, N.

10.1101/221432 — ecology — Posted on 2017-11-17

698 Nutrient homeostasis and mechanisms related to nutrient retention by wetland macrophytes in a subtropical wetland.

Julian, P.; Gerber, S.; King, J.; Wright, A. L.

10.1101/221465 — ecology — Posted on 2017-11-17

699 Diel predator activity drives a dynamic landscape of fear

Kohl, M. T.; Stahler, D. R.; Metz, M. C.; Forester, J. D.; Kauffman, M. J.; Varley, N.; White, P. J.; Smith, D. W.; MacNulty, D. R.

10.1101/221440 — ecology — Posted on 2017-11-17

700 Hominin-specific NOTCH2 paralogs expand human cortical neurogenesis through regulation of Delta/Notch interactions.

Suzuki, I. K.; Gacquer, D.; Van Heurck, R.; Kumar, D.; Wojno, M.; Bilheu, A.; Herpoel, A.; Cheron, J.; Polleux, F.; Detours, V.; Vanderhaeghen, P.

10.1101/221358 — developmental biology — Posted on 2017-11-17

701 Hominin-specific NOTCH2 paralogs expand human cortical neurogenesis through regulation of Delta/Notch interactions.

Suzuki, I. K.; Gacquer, D.; Van Heurck, R.; Kumar, D.; Wojno, M.; Bilheu, A.; Herpoel, A.; Cheron, J.; Polleux, F.; Detours, V.; Vanderhaeghen, P.

10.1101/221358 — developmental biology — Posted on 2017-11-17

702 LEM-3 is a midbody-tethered DNA nuclease that resolves chromatin bridges during cytokinesis

HONG, Y.; Sonneville, R.; Wang, B.; Scheidt, V.; Meier, B.; Woglar, A.; Demetriou, S.; Labib, K.; Jantsch, V.; Gartner, A.

10.1101/221291 — cell biology — Posted on 2017-11-17

703 Optical crosstalk in SPAD arrays for high-throughput single-molecule fluorescence spectroscopy

Ingargiola, A.; Segal, M.; Gulinatti, A.; Rech, I.; Labanca, I.; Maccagnani, P.; Ghioni, M.; Weiss, S.; Michalet, X.

10.1101/207118 — biophysics — Posted on 2017-11-17

704 Dynamics of a Form-Fitting Protein in a Nanopore: Avidin in ClyA

Lu, B.; Stokes, C.; Fahie, M.; Chen, M.; Golovchenko, J. A.; Hau, L. V.

10.1101/221457 — biophysics — Posted on 2017-11-17

705 Flex ddG: Rosetta ensemble-based estimation of changes in protein-protein binding affinity upon mutation

Barlow, K. A.; O Conchuir, S.; Thompson, S.; Suresh, P.; Lucas, J. E.; Heinonen, M.; Kortemme, T.

10.1101/221689 — biophysics — Posted on 2017-11-17

706 SV2: Accurate Structural Variation Genotyping and De Novo Mutation Detection

Antaki, D.; Brandler, W. M.; Sebat, J.

10.1101/113498 — bioinformatics — Posted on 2017-11-17

707 CRISPys: Optimal sgRNA design for editing multiple members of a gene family using the CRISPR system

Hyams, G.; Abadi, S.; Avni, A.; Halperin, E.; Shani, E.; Mayrose, I.

10.1101/221341 — bioinformatics — Posted on 2017-11-17

708 Simple statistical identification and removal of contaminant sequences in marker-gene and metagenomics data

Davis, N. M.; Proctor, D.; Holmes, S. P.; Relman, D. A.; Callahan, B. J.

10.1101/221499 — bioinformatics — Posted on 2017-11-17

709 CapsidMesh: atomic-detail structured mesh representation of icosahedral viral capsids for the study of their physical properties

Alonzo-Velazquez, J. L.; Botello-Rionda, S.; Herrera-Guzman, R.; Carrillo-Tripp, M.

10.1101/221663 — bioinformatics — Posted on 2017-11-17

710 Clust: automatic extraction of optimal co-expressed gene clusters from gene expression data

Abu-Jamous, B.; Kelly, S.

10.1101/221309 — bioinformatics — Posted on 2017-11-17

711 TKSA-MC: A Web Server for rational mutation through the optimization of protein charge interactions

Contessoto, V. G.; de Oliveira, V. M.; Fernandes, B. R.; Slade, G. G.; Leite, V. B. P.

10.1101/221556 — bioinformatics — Posted on 2017-11-17

712 Partitioning of semisynthetic lipidated N-Ras in lipid raft nanodomains determined by FRET to lipid domain markers

Shishina, A.; Kovrigina, E.; Galiakhmetov, A.; Rathore, R.; Kovrigin, E. L.

10.1101/221382 — biochemistry — Posted on 2017-11-17

713 Validating Antibodies for Quantitative Western Blot Measurements with Microwestern Array

Koch, R. J.; Barrette, A. M.; Stern, A. D.; Hu, B.; Azeloglu, E. U.; Iyengar, R.; Birtwistle, M. R.

10.1101/221523 — biochemistry — Posted on 2017-11-17

714 Atypical domain communication and domain functions of a Hsp110 chaperone

Kumar, V.; Peter, J. J.; Sagar, A.; Ray, A.; Ashish, ; mapa, k.

10.1101/220798 — biochemistry — Posted on 2017-11-17

715 Deficiency of global genome nucleotide excision repair explains mutational signature observed in cancer

Jager, M.; Blokzijl, F.; Kuijk, E.; Vougioukalaki, M.; Janssen, R.; Besselink, N.; Boymans, S.; de Ligt, J.; Hoeijmakers, J.; Pothof, J.; van Boxtel, R.; Cuppen, E.

10.1101/221168 — molecular biology — Posted on 2017-11-17

716 The global distribution and spread of the mobilized colistin resistance gene mcr-1

Wang, R.; van Dorp, L.; Shaw, L.; Bradley, P.; Wang, Q.; Wang, X.; Jin, L.; Zhang, Q.; Liu, Y.; Rieux, A.; Dorai-Schneiders, T.; Weinert, L. A.; Iqbal, Z.; Didelot, X.; Wang, H.; Balloux, F.

10.1101/220921 — microbiology — Posted on 2017-11-17

717 Ecological Insights from the Evolutionary History of Microbial Innovations

Muscarella, M. E.; O'Dwyer, J. P.

10.1101/220939 — microbiology — Posted on 2017-11-17

718 Real-time analysis of nanopore-based metagenomic sequencing from orthopaedic device infection

Sanderson, N. D.; Street, T. L.; Foster, D.; Swann, J.; Atkins, B. L.; Brent, A. J.; McNally, M. A.; Oakley, S.; Taylor, A.; Peto, T. E. A.; Crook, D.; Eyre, D. W.

10.1101/220616 — microbiology — Posted on 2017-11-17

719 Significant abundance of cis configurations of mutations in diploid human genomes

Hoehe, M. R.; Herwig, R.; Mao, Q.; Peters, B. A.; Drmanac, R.; Church, G. M.; Huebsch, T.

10.1101/221085 — genomics — Posted on 2017-11-17

720 Reorientation of the primary body axis by ectopic embryonic cWnt signaling.

Martindale, M. Q.; Wijesena, N.

10.1101/220988 — developmental biology — Posted on 2017-11-17

721 GDF15 Concentrations in Maternal Serum Associated with Vomiting in Pregnancy: the Cambridge Baby Growth Study

Petry, C. J.; Ong, K. K.; Burling, K. A.; Barker, P.; Perry, J. R.; Acerini, C. L.; Hughes, I. A.; Dunger, D. B.; O'Rahilly, S.

10.1101/221267 — developmental biology — Posted on 2017-11-17

722 Stopping Transformed Growth with Cytoskeletal Proteins: Turning a Devil into an Angel

Yang, B.; Wolfenson, H.; Nakazawa, N.; Liu, S.; Hu, J.; Sheetz, M.

10.1101/221176 — cell biology — Posted on 2017-11-17

723 Mechanical changes in proteins with large-scale motions highlight the formation of structural locks

Sacquin-Mora, S.

10.1101/221077 — biophysics — Posted on 2017-11-17

724 glactools: a command-line toolset for the management of genotype likelihoods and allele counts

Renaud, G.

10.1101/221127 — bioinformatics — Posted on 2017-11-17

725 Fast ordered sampling of DNA sequence variants

Greenberg, A. J.

10.1101/220871 — bioinformatics — Posted on 2017-11-17

726 Efficient online-group-screening designs for agent identification

Gao, T.; Finkel, O.; Dangl, J.; Jojic, V.

10.1101/220863 — bioinformatics — Posted on 2017-11-17

727 Newly identified relatives of botulinum neurotoxins shed light on their molecular evolution

Mansfield, M. J.; Wentz, T. G.; Zhang, S.; Lee, E. J.; Dong, M.; Sharma, S. K.; Doxey, A. C.

10.1101/220806 — bioinformatics — Posted on 2017-11-17

728 Closed-loop feedback control for microfluidic systems through automated capacitive fluid height sensing

Soenksen Martinez, L. R.; Kassis, T.; Noh, M.; Griffith, L. G.; Trumper, D. L.

10.1101/221002 — bioengineering — Posted on 2017-11-17

729 Multi-Funnel Landscape of the Fold-Switching Protein RfaH-CTD

Bernhardt, N. A.; Hansmann, U.

10.1101/221143 — biochemistry — Posted on 2017-11-17

730 The study of animal behaviour as a physical science

Brown, A. E.; de Bivort, B.

10.1101/220855 — animal behavior and cognition — Posted on 2017-11-17

731 Identification of USP7 as an essential component to maintain integrity and function of non-canonical PRC1.1 in leukemia

Maat, H.; Jaques, J.; Rodriguez Lopez, A.; de Vries, M. P.; Gravesteijn, C.; Brouwers-Vos, A.; Huls, G.; Vellenga, E.; van den Boom, V.; Schuringa, J. J.

10.1101/221093 — cancer biology — Posted on 2017-11-17

732 Cholesterol Synthesis Pathway Genes in Prostate Cancer are consistently downregulated when tissue confounding is minimized.

Rye, M. B.; Bertilsson, H.; Andersen, M. K.; Rise, K.; Bathen, T. F.; Drablos, F.; Tessem, M.-B.

10.1101/220400 — cancer biology — Posted on 2017-11-17

733 Wide-field dynamic monitoring of immune cell trafficking in murine models of glioblastoma

SoRelle, E. D.; Yecies, D. W.; Liba, O.; Bennett, C. F.; Graef, C.-M.; Dutta, R.; Mitra, S. S.; Joubert, L.-M.; Cheshier, S. H.; Grant, G. A.; de la Zerda, A.

10.1101/220954 — bioengineering — Posted on 2017-11-17

734 Cross-Site Comparison of Ribosomal Depletion Kits for Illumina RNAseq Library Construction

Herbert, Z. T.; Kershner, J. P.; Butty, V. L.; Thimmapuram, J.; Choudhari, S.; Alekseyev, Y. O.; Fan, J.; Podnar, J. W.; Wilcox, E.; Gipson, J.; Gillaspy, A.; Jepsen, K.; BonDurant, S. S.; Morris, K.; Berkeley, M.; LeClerc, A.; Simpson, S. D.; Sommerville, G.; Grimmett, L.; Adams, M.; Levine, S. S.

10.1101/212639 — genomics — Posted on 2017-11-16

735 Raw sequence to target gene prediction: An integrated inference pipeline for ChIP-seq and RNA-seq datasets

Wani, N.; Raza, K.

10.1101/220152 — systems biology — Posted on 2017-11-16

736 A robust and tunable mitotic oscillator in artificial cells

Guan, Y.; Li, Z.; Wang, S.; Barnes, P. M.; Liu, X.; Xu, H.; Jin, M.; Liu, A. P.; Yang, Q.

10.1101/218263 — systems biology — Posted on 2017-11-16

737 Comparative omics analyses differentiate Mycobacterium tuberculosis and Mycobacterium bovis and reveal distinct macrophage responses to infection with the human and bovine tubercle bacilli

Malone, K. M.; Rue-Albrecht, K.; Magee, D. A.; Conlon, K.; Schubert, O.; Nalpas, N. C.; Browne, J. A.; Smyth, A.; Gormley, E.; Aebersold, R.; MacHugh, D.; Gordon, S. V.

10.1101/220624 — systems biology — Posted on 2017-11-16

738 Current CRISPR gene drive systems are likely to be highly invasive in wild populations

Noble, C.; Adlam, B.; Church, G. M.; Esvelt, K. M.; Nowak, M. A.

10.1101/219022 — synthetic biology — Posted on 2017-11-16

739 Secondary metabolites and the antimicrobial potential of five different Coleus species in response to salinity stress

Kotagiri, D.; Khasim Beebi, S.; Viswanatha Chaitanya, K.

10.1101/220368 — plant biology — Posted on 2017-11-16

740 Propofol induces metabolic reprogramming and cell death in a mitochondrial electron transport chain-dependent manner

Sumi, C.; Okamoto, A.; Tanaka, H.; Nishi, K.; Kusunoki, M.; Shoji, T.; Uba, T.; Matsuo, Y.; Adachi, T.; Hayashi, J.-I.; Takenaga, K.; Hirota, K.

10.1101/181933 — pharmacology and toxicology — Posted on 2017-11-16

741 Mapping neurons and brain regions underlying sensorimotor decisions and sequences

Jovanic, T.; Masson, J.-B.; Truman, J. W.; Zlatic, M.

10.1101/215236 — neuroscience — Posted on 2017-11-16

742 Limitations of proposed signatures of Bayesian confidence

Adler, W. T.; Ma, W. J.

10.1101/218222 — neuroscience — Posted on 2017-11-16

743 Theta Oscillations Organize Spiking Activity in Higher-Order Visual Thalamus during Sustained Attention

Yu, C.; Stitt, I.; Li, Y.; Zhou, Z. C.; Sellers, K.; Frohlich, F.

10.1101/219626 — neuroscience — Posted on 2017-11-16

744 Ghost interactions in MEG/EEG source space: A note of caution on inter-areal coupling measures

Palva, J. M.; Wang, S. H.; Palva, S.; Zhigalov, A.; Monto, S.; Brookes, M. J.; Schoffelen, J.-M.; Jerbi, K.

10.1101/220459 — neuroscience — Posted on 2017-11-16

745 Behavioral and neural representations of spatial directions across words, schemas, and images

Weisberg, S. M.; Marchette, S. A.; Chatterjee, A.

10.1101/220137 — neuroscience — Posted on 2017-11-16

746 Differential representation of articulatory gestures and phonemes in motor, premotor, and inferior frontal cortices

Mugler, E. M.; Tate, M. C.; Livescu, K.; Templer, J. W.; Goldrick, M. A.; Slutzky, M. W.

10.1101/220723 — neuroscience — Posted on 2017-11-16

747 Organization of Neural Population Code in Mouse Visual System

Esfahany, K.; Siergiej, I.; Zhao, Y.; Park, I. M.

10.1101/220558 — neuroscience — Posted on 2017-11-16

748 Cerebellar granule cell precursors can extend processes, undergo short migratory movements and express postmitotic markers before mitosis in the chick EGL

Hanzel, M.; Wingate, R. J.

10.1101/220715 — neuroscience — Posted on 2017-11-16

749 Age-accelerated cognitive decline in asymptomatic adults with CSF β-amyloid

Clark, L.; Berman, S.; Norton, D.; Koscik, R.; Jonaitis, E.; Blennow, K.; Bendlin, B.; Asthana, S.; Johnson, S.; Zetterberg, H.; Carlsson, C.

10.1101/220756 — neuroscience — Posted on 2017-11-16

750 Temporal neural mechanisms underlying conscious access to different levels of facial stimulus contents

Hsu, S.-M.; Yang, Y.-f.

10.1101/220426 — neuroscience — Posted on 2017-11-16

751 ABCF ATPases involved in protein synthesis, ribosome assembly and antibiotic resistance: structural and functional diversification across the tree of life

Murina, V.; Kasari, M.; Reith, M.; Hauryliuk, V.; Atkinson, G.

10.1101/220046 — molecular biology — Posted on 2017-11-16

752 PWWP INTERACTOR OF POLYCOMBS (PWO1) links PcG-mediated gene repression to the nuclear lamina in Arabidopsis.

Mikulski, P.; Hohenstatt, M. L.; Farrona, S.; Smaczniak, C.; Kaufmann, K.; Angenent, G.; Schubert, D.

10.1101/220541 — molecular biology — Posted on 2017-11-16

753 Antisense lncRNAs expression correlates with attenuation of highly transcribed genes in fission yeast

WERY, M.; GAUTIER, C.; DESCRIMES, M.; YODA, M.; MIGEOT, V.; HERMAND, D.; MORILLON, A.

10.1101/220707 — molecular biology — Posted on 2017-11-16

754 Spatial variation of the native colon microbiota in healthy adults

Flynn, K. J.; Ruffin, M. T.; Turgeon, D. K.; Schloss, P. D.

10.1101/189886 — microbiology — Posted on 2017-11-16

755 Novel bacterial lineages associated with boreal moss species

Holland-Moritz, H.; Stuart, J.; Lewis, L. R.; Miller, S.; Mack, M. C.; McDaniel, S. F.; Fierer, N.

10.1101/219659 — microbiology — Posted on 2017-11-16

756 Evolutionary outcomes of plasmid-CRISPR conflicts in an opportunistic pathogen

Huo, W.; Price, V. J.; Sharifi, A.; Zhang, M. Q.; Palmer, K. L.

10.1101/220467 — microbiology — Posted on 2017-11-16

757 MetQy: an R package to query metabolic functions of genes and genomes

Martinez-Vernon, A.; Farrell, F.; soyer, o.

10.1101/215525 — microbiology — Posted on 2017-11-16

758 Genomic, proteomic, and phylogenetic analysis of spounaviruses indicates paraphyly of the order Caudovirales

Barylski, J.; Enault, F.; Dutilh, B. E.; Schuller, M. B.; Edwards, R. A.; Gillis, A.; Klumpp, J.; Knezevic, P.; Krupovic, M.; Kuhn, J. H.; Lavigne, R.; Oksanen, H. M.; Sullivan, M. B.; Wittmann, J.; Tolstoy, I.; Brister, J. R.; Kropinski, A. M.; Adriaenssens, E. M.

10.1101/220434 — microbiology — Posted on 2017-11-16

759 Fungal communities associated with the eastern larch beetle: diversity and variation within developmental stages

Durand, A.-A.; Buffet, J.-P.; Constant, P.; Deziel, E.; Guertin, C.

10.1101/220780 — microbiology — Posted on 2017-11-16

760 TGF-β1 enhances mouse mast cell release of IL-6 and IL-13

Lyons, D. O.; Plewes, M. R.; Pullen, N. A.

10.1101/220665 — immunology — Posted on 2017-11-16

761 The Evolutionary Genomic Dynamics of Peruvians Before, During, and After the Inca Empire

Harris, D. N.; Song, W.; Shetty, A. C.; Lavano, K.; Caceres, O.; Padilla, C.; Borda, V.; Tarazona, D.; Trujillo, O.; Sanchez, C.; Kessler, M. D.; Galarza, M.; Capristano, S.; Montejo, H.; Flores-Villanueva, P. O.; Tarazona-Santos, E.; O'Connor, T. D.; Guio, H.

10.1101/219808 — genomics — Posted on 2017-11-16

762 Genome variants altering gene splicing in bovine are extensively shared between tissues

Xiang, R.; Hayes, B. J.; Vander Jagt, C. J.; MacLeod, I. M.; Khansefid, M.; Bowman, P. J.; Prowse-Wilkins, C. P.; Reich, C. M.; Mason, B. A.; Garner, J. B.; Marett, L. C.; Chen, Y.; Bolormaa, S.; Daetwyler, H. D.; Chamberlain, A. J.; Goddard, M. E.

10.1101/220251 — genomics — Posted on 2017-11-16

763 The Evolutionary Genomic Dynamics of Peruvians Before, During, and After the Inca Empire

Harris, D. N.; Song, W.; Shetty, A. C.; Levano, K.; Caceres, O.; Padilla, C.; Borda, V.; Tarazona, D.; Trujillo, O.; Sanchez, C.; Kessler, M. D.; Galarza, M.; Capristano, S.; Montejo, H.; Flores-Villanueva, P. O.; Tarazona-Santos, E.; O'Connor, T. D.; Guio, H.

10.1101/219808 — genomics — Posted on 2017-11-16

764 Differential gene expression analysis tools exhibit substandard performance for long non-coding RNA-sequencing data

Assefa, A. T.; De Paepe, K.; Everaert, C.; Mestdagh, P.; Thas, O.; Vandesompele, J.

10.1101/220129 — genomics — Posted on 2017-11-16

765 Sex Chromosome Dosage Effects On Gene Expression In Humans

Raznahan, A.; Parikshak, N.; Chandran, V.; Blumenthal, J.; Clasen, L.; Alexander-Bloch, A.; Zinn, A.; Wangsa, D.; Wise, J.; Murphy, D.; Bolton, P.; Ried, T.; Ross, J.; Giedd, J.; Geschwind, D.

10.1101/137752 — genomics — Posted on 2017-11-16

766 A map of constrained coding regions in the human genome.

Havrilla, J. M.; Pedersen, B. S.; Layer, R. M.; Quinlan, A. R.

10.1101/220814 — genomics — Posted on 2017-11-16

767 Origin and evolution of the nuclear auxin response system

Mutte, S.; Kato, H.; Rothfels, C.; Melkonian, M.; Wong, G. K.-S.; Weijers, D.

10.1101/220731 — genomics — Posted on 2017-11-16

768 HAPDeNovo: a haplotype-based approach for filtering and phasing de novo mutations in linked read sequencing data

Xin, Z.; Batzoglou, S.; Sidow, A.; Zhang, L.

10.1101/220830 — genomics — Posted on 2017-11-16

769 Method to estimate the approximate samples size that yield a certain number of significant GWAS signals in polygenic traits

Bacanu, S.-A.; Kendler, K. S.

10.1101/219733 — genetics — Posted on 2017-11-16

770 Reduced representation optical methylation mapping (R2OM2).

Grunwald, A.; Sharim, H.; Gabrieli, T.; Michaeli, Y.; Torchinsky, D.; Arieli, R.; Juhasz, M.; Wagner, K. R.; Pevsner, J.; Reifenberger, J.; Hastie, A. R.; Cao, H.; Weinhold, E.; Ebenstein, Y.

10.1101/113522 — genetics — Posted on 2017-11-16

771 SMN1 and SMN2 Copy Number Determination by droplet digital PCR (ddPCR) based on Extreme Value Theory for Threshold Estimation

Niknazar, M.; Jansen, M.; Puig, O.

10.1101/220020 — genetics — Posted on 2017-11-16

772 Multivariate genome-wide association study of rapid automatized naming and rapid alternating stimulus in Hispanic and African American youth.

Truong, D.; Adams, A. K.; Boada, R.; Frijters, J. C.; Hill, D. E.; Lovett, M. W.; Mahone, M. E.; Willcutt, E. G.; Wolf, M.; Pediatric, Imaging, Neurocognition, & Genetics Con, ; Defries, J. C.; Fisher, S. E.; Francks, C.; Gialluisi, A.; Olson, R. K.; Pennington, B.; Smith, S. D.; Bosson-Heenan, J.; Gruen, J. R.

10.1101/202929 — genetics — Posted on 2017-11-16

773 Widespread Genotype-Phenotype Correlations in Intellectual Disability

Casanova, E. L.; Gerstner, Z.; Sharp, J. L.; Casanova, M. F.; Feltus, F. A.

10.1101/220608 — genetics — Posted on 2017-11-16

774 Germ line aging and regional epigenetic instability: age prediction using human sperm DNA methylation signatures

Jenkins, T. G.; Aston, K. I.; Carrell, D. T.

10.1101/220764 — genetics — Posted on 2017-11-16

775 Bayesian Inference Of Phylogenetic Networks From Bi-allelic Genetic Markers

Zhu, J.; Wen, D.; Yu, Y.; Meudt, H.; Nakhleh, L.

10.1101/143545 — evolutionary biology — Posted on 2017-11-16

776 RelTime relaxes the strict molecular clock throughout the phylogeny

Battistuzzi, F. U.; Tao, Q.; Jones, L.; Tamura, K.; Kumar, S.

10.1101/220194 — evolutionary biology — Posted on 2017-11-16

777 The Basic Reproductive Number for Disease Systems with Multiple Coupled Heterogeneities

Lloyd, A.; Kitron, U.; Perkins, A.; Vazquez Prokopec, G.; Waller, L.

10.1101/220004 — epidemiology — Posted on 2017-11-16

778 Zika: An ongoing threat to women and infants

Coimbra, B. M.; Coelho, F. C.; Armstrong, M.; Saraceni, V.; Lemos, C.

10.1101/220640 — epidemiology — Posted on 2017-11-16

779 The Association between Tuberculosis and Diphtheria

Coleman, S.

10.1101/219584 — epidemiology — Posted on 2017-11-16

780 Household Members Do Not Contact Each Other at Random: Implications for Infectious Disease Modelling

Goeyvaerts, N.; Santermans, E.; Potter, G.; Torneri, A.; Van Kerckhove, K.; Willem, L.; Aerts, M.; Beutels, P.; Hens, N.

10.1101/220202 — epidemiology — Posted on 2017-11-16

781 Is the HIV epidemic over? Investigating population dynamics using Bayesian methodology to estimate epidemiological parameters for a system of stochastic differential equations

Dale, R.; Guo, B.

10.1101/219832 — epidemiology — Posted on 2017-11-16

782 Reactive and pre-emptive vaccination strategies to control hepatitis E infection in emergency and refugee settings: a modelling study.

Cooper, B. S.; White, L. J.; Siddiqui, M. R.

10.1101/219154 — epidemiology — Posted on 2017-11-16

783 Analyzing ecological networks of species interactions

Delmas, E.; Besson, M.; Brice, M.-H.; Burkle, L.; Dalla Riva, G. V.; Fortin, M.-J.; Gravel, D.; Guimaraes, P.; Hembry, D.; Newman, E.; Olesen, J. M.; Pires, M.; Yeakel, J. D.; Poisot, T.

10.1101/112540 — ecology — Posted on 2017-11-16

784 Boreal river impoundments caused little change in fish diversity but clear community assemblage shifts: A multi-scale analysis

Turgeon, K.; Turpin, C.; Gregory-Eaves, I.

10.1101/129403 — ecology — Posted on 2017-11-16

785 Stoichiometric relationships amongst ecosystem compartments of a subtropical treatment wetland

Julian, P.; Gerber, S.; Bhomia, R.; King, J.; Osborne, T. Z.; Wright, A. L.

10.1101/220186 — ecology — Posted on 2017-11-16

786 Predator-prey feedback in a gyrfalcon-ptarmigan system?

Barraquand, F.; Nielsen, O. K.

10.1101/220038 — ecology — Posted on 2017-11-16

787 On the Calculation of Betweenness Centrality in Marine Connectivity Studies Using Transfer Probabilities

Costa, A.; Petrenko, A. A.; Guizien, K.; Doglioli, A. M.

10.1101/219881 — ecology — Posted on 2017-11-16

788 Rethinking the importance of ecological networks through the glass of environmental variations

Cenci, S.; Song, C.; Saavedra, S.

10.1101/219691 — ecology — Posted on 2017-11-16

789 Influence of APOA5 locus on the treatment efficacy of three statins: evidence from a randomized pilot study in Chinese subjects

Hua, S.; Ma, C.; Zhang, J.; Li, J.; Wu, W.; Xu, N.; Luo, G.; Zhao, J.

10.1101/213629 — clinical trials — Posted on 2017-11-16

790 Noise-driven Cell Differentiation and the Emergence of Organization

Safdari, H.; Kalirad, A.; Picioreanu, C.; Tusserkani, R.; Sadeghi, M.

10.1101/220525 — cell biology — Posted on 2017-11-16

791 A FRET based biosensor for measuring Gα13 activation in single cells

Mastop, M.; Reinhard, N. R.; Zuconelli, C. R.; Terwey, F.; Gadella, T. W. J.; van Unen, J.; Adjobo-Hermans, M. J. W.; Goedhart, J.

10.1101/220632 — cell biology — Posted on 2017-11-16

792 Ribosome profiling uncovers selective mRNA translation associated with eIF2 phosphorylation in erythroid progenitors

Paolini, N. A.; Moore, K. S.; Di Summa, F. M.; Fokkema, I. F. A. C.; 't Hoen, P. A. C.; von LIndern, M. M.

10.1101/216234 — cell biology — Posted on 2017-11-16

793 Hypothesis: Hypoxia induces de novo synthesis of NeuGc gangliosides in humans through CMAH domain substitute

Bousquet, A. P. A.; Sandvig, J. A.; Edin, N. F. J.; Krengel, U.

10.1101/125617 — cancer biology — Posted on 2017-11-16

794 Dissecting single cell molecular spatiotemporal mobility and clustering at Focal Adhesions in polarised cells by fluorescence fluctuation spectroscopy methods

Bernardino de la Serna, J.; Garcia, E.

10.1101/220491 — biophysics — Posted on 2017-11-16

795 Conversion between parallel and antiparallel β-sheets in wild-type and Iowa mutant fibrils

Xi, W.; Hansmann, U.

10.1101/220749 — biophysics — Posted on 2017-11-16

796 ChIPdig: a comprehensive user-friendly tool for mining multi-sample ChIP-seq data

Esse, R.; Grishok, A.

10.1101/220079 — bioinformatics — Posted on 2017-11-16

797 Latent variable model for aligning barcoded short-reads improves downstream analyses

Shajii, A.; Numanagic, I.; Berger, B.

10.1101/220236 — bioinformatics — Posted on 2017-11-16

798 What are the most influencing factors in reconstructing a reliable transcriptome assembly?

Ghaffari, N.; Abante, J.; Singh, R.; Blood, P. D.; Pipes, L.; Mason, C.; Johnson, C. D.

10.1101/220269 — bioinformatics — Posted on 2017-11-16

799 Salt-bridge Dynamics in Intrinsically Disordered Proteins: A trade-off between electrostatic interactions and structural flexibility

Basu, S.; Biswas, P.

10.1101/220392 — bioinformatics — Posted on 2017-11-16

800 miRAW: A deep learning approach to predict miRNA targets by analyzing whole miRNA transcripts

Pla Planas, A.; Zhong, X.; Rayner, S.

10.1101/220483 — bioinformatics — Posted on 2017-11-16

801 CPdock: The Complementarity Plot for Docking of Proteins: Implementing Multi-dielectric Continuum Electrostatics

Basu, S.

10.1101/185686 — bioinformatics — Posted on 2017-11-16

802 LSX: Automated reduction of gene-specific lineage evolutionary rate heterogeneity for multi-gene phylogeny inference

Rivera-Rivera, C. J.; Montoya-Burgos, J. I.

10.1101/220053 — bioinformatics — Posted on 2017-11-16

803 The fractured landscape of RNA-seq alignment: The default in our STARs

Ballouz, S.; Dobin, A.; Gingeras, T. R.; Gillis, J.

10.1101/220681 — bioinformatics — Posted on 2017-11-16

804 Systematic interrogation of diverse Omic data reveals interpretable, robust, and generalizable transcriptomic features of clinically successful therapeutic targets

Rouillard, A.; Hurle, M. R.; Agarwal, P.

10.1101/220848 — bioinformatics — Posted on 2017-11-16

805 Decision by sampling implements efficient coding of psychoeconomic functions

Bhui, R.; Gershman, S. J.

10.1101/220277 — animal behavior and cognition — Posted on 2017-11-16

806 Variational Treatment of Trial-by-Trial Drift-Diffusion Models of Behaviour

Moens, V.; Zenon, A.

10.1101/220517 — animal behavior and cognition — Posted on 2017-11-16

807 Do Sigmoidal Acquisition Curves Indicate Conformity?

Smaldino, P. E.; Aplin, L. M.; Farine, D. R.

10.1101/159038 — animal behavior and cognition — Posted on 2017-11-16

808 A semi-synthetic strategy for derivatization of the violacein natural product scaffold

Lai, H.-E.; Chee, S. M.; Morgan, M.; Moore, S. J.; Polizzi, K. M.; Freemont, P. S.

10.1101/202523 — synthetic biology — Posted on 2017-11-15

809 Impaired Cu-Zn superoxide dismutase (SOD1) and calcineurin (Cn) interaction in ALS: A presumed consequence for TDP-43 and zinc aggregation in Tg SOD1G93A rodent spinal cord tissue.

Kim, J. M.; Billington, E.; Reyes, A.; Notarianni, T.; Sage, J. M.; Agbas, E.; Taylor, M.; Monast, I.; Stanford, J. A.; Agbas, A.

10.1101/220210 — neuroscience — Posted on 2017-11-15

810 Suboptimal eye movements for seeing fine details

Agaoglu, M. N.; Sheehy, C. K.; Tiruveedhula, P.; Roorda, A.; Chung, S. T. L.

10.1101/220319 — neuroscience — Posted on 2017-11-16

811 Gender-biased perceptions of important ecology articles

Bradshaw, C. J. A.; Courchamp, F.

10.1101/219824 — ecology — Posted on 2017-11-16

812 Comparison of multiple transcriptomes exposes unified and divergent features of quiescent and activated skeletal muscle stem cells

Pietrosemoli, N.; Mella, S.; Yennek, S.; Baghdadi, M.; Sakai, H.; Sambasivan, R.; Pala, F.; DI GIROLAMO, D.; Tajbakhsh, S.

10.1101/219998 — cell biology — Posted on 2017-11-15

813 Assessment of the aging of the brown adipose tissue by 18F-FDG PET/CT imaging in the progeria mouse model LmnaG609G/G609G

Wang, Z.; Xu, X.; Liu, Y.; Gao, Y.; Ma, W.; Yang, W.; Kang, F.; Liu, B.; Wang, J.

10.1101/220061 — cell biology — Posted on 2017-11-15

814 Exploring Applications of Crowdsourcing to Cryo-EM

Bruggemann, J.; Lander, G. C.; Su, A. I.

10.1101/220145 — bioinformatics — Posted on 2017-11-15

815 Extracting biological age from biomedical data via deep learning: too much of a good thing?

Pyrkov, T. V.; Slipensky, K.; Barg, M.; Kondrashin, A.; Zhurov, B.; Zenin, A.; Pyatnitskiy, M.; Menshikov, L.; Markov, S.; Fedichev, P. O.

10.1101/219162 — bioinformatics — Posted on 2017-11-16

816 Per-sample immunoglobulin germline inference from B cell receptor deep sequencing data

Ralph, D. K.; Matsen, F. A.

10.1101/220285 — bioinformatics — Posted on 2017-11-16

817 Pathway crosstalk enables cells to interpret TGF-β duration

Zhang, J.; Tian, X.-J.; Chen, Y.-J.; Wang, W.; Watkins, S.; Xing, J.

10.1101/134106 — systems biology — Posted on 2017-11-15

818 Embryonic circular RNAs at tandem duplicated genes in zebrafish present new paradigm in gene expression

Chong-Morrison, V.; Sauka-Spengler, T.

10.1101/220160 — molecular biology — Posted on 2017-11-15

819 Fusicatenibacter Is Associated with Kefir Drinking

Sprague, R.

10.1101/218313 — microbiology — Posted on 2017-11-15

820 Transgenerational Epigenetic Inheritance Factors Localize to Spatiallyand Temporally Ordered Liquid Droplet Assemblages

Wan, G.; Fields, B.; Spracklin, G.; Phillips, C.; Kennedy, S.

10.1101/220111 — genetics — Posted on 2017-11-15

821 Optimizing gene expression by adapting splicing

Frumkin, I.; Yofe, I.; Bar-Ziv, R.; Voichek, Y.; Pilpel, Y.

10.1101/220228 — evolutionary biology — Posted on 2017-11-15

822 Quantitative imaging of chromatin decompaction in living cells

Dultz, E.; Mancini, R.; Polles, G.; Vallotton, P.; Alber, F.; Weis, K.

10.1101/219253 — cell biology — Posted on 2017-11-15

823 Actomyosin contractility modulates Wnt signaling through adherens junction stability

Hall, E. T.; Hoesing, E. A.; Sinkovics, E. D.; Verheyen, E. M.

10.1101/220178 — cell biology — Posted on 2017-11-15

824 Nuclear Abl Drives miR-34c Transfer by Extracellular Vesicles to Induce Radiation Bystander Effects

Rastogi, S.; Hwang, A.; Chan, J.; Wang, J. Y.

10.1101/209767 — cell biology — Posted on 2017-11-15

825 Bringing Diffuse X-ray Scattering Into Focus

Wall, M.; Wolff, A.; Fraser, J. S.

10.1101/219113 — biophysics — Posted on 2017-11-15

826 The impact factor fallacy

Paulus, F. M.; Cruz, N.; Krach, S.

10.1101/108027 — scientific communication and education — Posted on 2017-11-15

827 Effects of polyploidy on response of Dunaliella salina to salinity

Mansouri, H.; Soltani Nezhad, F.

10.1101/219840 — plant biology — Posted on 2017-11-15

828 Multiple spin echos in cerebral dynamics: Evidence for spontaneous symmetry breaking during pulsation

Kerskens, C.; Lopez Perez, D.

10.1101/219931 — physiology — Posted on 2017-11-15

829 Voluntary control of illusory contour formation

Harrison, W.; Rideaux, R.

10.1101/219279 — neuroscience — Posted on 2017-11-15

830 EEG Decoding Reveals the Temporal Dynamics and Functional Relevance of Goal-Relevant Representations

Hubbard, J.; Kikumoto, A.; Mayr, U.

10.1101/219741 — neuroscience — Posted on 2017-11-15

831 Changes in global brain connectivity in LSD-induced altered states of consciousness are attributable to the 5-HT2A receptor

Preller, K. H.; Burt, J. B.; Ji, J. L.; Schleifer, C.; Adkinson, B.; Staempfli, P.; Repovs, G.; Krystal, J. H.; Murray, J. D.; Vollenweider, F. X.; Anticevic, A.

10.1101/219956 — neuroscience — Posted on 2017-11-15

832 Widespread shorter cortical adaptation in dyslexia

Jaffe-Dax, S.; Kimel, E.; Ahissar, M.

10.1101/219923 — neuroscience — Posted on 2017-11-15

833 Modification of scale-free electrophysiological activity induced by changes in excitatory-inhibitory balance is governed by the dynamics of multiple oscillatory relaxation processes

Muthukumaraswamy, S. D.; Liley, D. T.

10.1101/203786 — neuroscience — Posted on 2017-11-15

834 Vagal nerve stimulation triggers widespread responses and alters large-scale functional connectivity in the rat brain

Cao, J.; Lu, K.-H.; Powley, T. L.; Liu, Z.

10.1101/200220 — neuroscience — Posted on 2017-11-15

835 EEG Decoding Reveals the Temporal Dynamics and Functional Relevance of Goal-Relevant Representations in Humans

Hubbard, J.; Kikumoto, A.; Mayr, U.

10.1101/219741 — neuroscience — Posted on 2017-11-15

836 Distributed Rhythm Generators Underlie Caenorhabditis elegans Forward Locomotion

Fouad, A. D.; Teng, S.; Mark, J. R.; Liu, A.; Alvarez-Illera, P.; Ji, H.; Du, A.; Bhirgoo, P.; Cornblath, E.; Guan, A.; Fang-Yen, C.

10.1101/141911 — neuroscience — Posted on 2017-11-15

837 EEG Decoding Reveals the Temporal Dynamics and Functional Relevance of Goal-Relevant Representations in Humans

Hubbard, J.; Kikumoto, A.; Mayr, U.

10.1101/219741 — neuroscience — Posted on 2017-11-15

838 Needle in a haystack? A comparison of eDNA metabarcoding and targeted qPCR for detection of great crested newt (Triturus cristatus)

Harper, L. R.; Lawson Handley, L.; Hahn, C.; Boonham, N.; Rees, H. C.; Gough, K. C.; Lewis, E.; Adams, I. P.; Brotherton, P.; Phillips, S.; Haenfling, B.

10.1101/215897 — molecular biology — Posted on 2017-11-15

839 Identification of stable reference genes for quantitative PCR in koalas

Sarker, N.; Fabijan, J.; Emes, R. D.; Hemmatzadeh, F.; Meers, J.; Moreton, J.; Owen, H.; Seddon, J. M.; Simmons, G.; Speight, N.; Trott, D.; Woolford, L.; Tarlinton, R.

10.1101/215681 — molecular biology — Posted on 2017-11-15

840 Gene flow between divergent cereal- and grass-specific lineages of the rice blast fungus Magnaporthe oryzae

Gladieux, P.; Condon, B.; Ravel, S.; Soanes, D.; Nunes Maciel, J. L.; Nhani, A.; Chen, L.; Terauchi, R.; Lebrun, M.-H.; Tharreau, D.; Mitchell, T.; Pedley, K. F.; Valent, B.; Talbot, N.; Farman, M.; Fournier, E.

10.1101/161513 — microbiology — Posted on 2017-11-15

841 KKL-35 Exhibits Potent Antibiotic Activity Against Legionella Species Independently Of Trans-Translation Inhibition

Brunel, R.; Descours, G.; Durieux, I.; Doublet, P.; Jarraud, S.; Charpentier, X.

10.1101/135798 — microbiology — Posted on 2017-11-15

842 The antiviral mechanism of MxA revealed by a molecular docking-based structural model of the complex of MxA and influenza A virus NP/RNPs

Sun, Y.

10.1101/219915 — microbiology — Posted on 2017-11-15

843 Peptide Terminus Tilting: an Unusual conformational transition of MHC Class I Revealed by Molecular Dynamics Simulations

Sun, Y.; Tian, P.

10.1101/219873 — immunology — Posted on 2017-11-15

844 Genome-wide polygenic score to identify a monogenic risk-equivalent for coronary disease

Khera, A. V.; Chaffin, M.; Aragam, K.; Emdin, C. A.; Klarin, D.; Haas, M.; Roselli, C.; Natarajan, P.; Kathiresan, S.

10.1101/218388 — genomics — Posted on 2017-11-15

845 Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

10.1101/212357 — genomics — Posted on 2017-11-15

846 Hemimetabolous genomes reveal molecular basis of termite eusociality

Harrison, M. C.; Jongepier, E.; Robertson, H. M.; Arning, N.; Bitard-Feildel, T.; Chao, H.; Childers, C. P.; Dinh, H.; Doddapaneni, H.; Dugan, S.; Gowin, J.; Greiner, C.; Han, Y.; Hu, H.; Hughes, D. S. T.; Huylmans, A.-K.; Kemena, C.; Kremer, L. P. M.; Lee, S. L.; Lopez-Ezquerra, A.; Mallet, L.; Monroy-Kuhn, J. M.; Moser, A.; Murali, S. C.; Muzny, D. M.; Otani, S.; Piulachs, M.-D.; Poelchau, M.; Qu, J.; Schaub, F.; Wada-Katsumata, A.; Worley, K. C.; Xie, Q.; Ylla, G.; Poulsen, M.; Gibbs, R. A.; Schal, C.; Richards, S.; Belles, X.; Korb, J.; Bornberg-Bauer, E.

10.1101/181909 — evolutionary biology — Posted on 2017-11-15

847 The necessary emergence of structural complexity in self-replicating RNA populations

G. Oliver, C.; Reinharz, V.; Waldispühl, J.

10.1101/218990 — evolutionary biology — Posted on 2017-11-15

848 Same law, different results: comparative analysis of Endangered Species Act consultations by two federal agencies

Evansen, M.; Li, Y.-W.; Malcom, J.

10.1101/165647 — ecology — Posted on 2017-11-15

849 Anisotropic Cellular Mechanoresponse for Radial Size Maintenance of Developing Epithelial Tubes

Hirashima, T.; Adachi, T.

10.1101/172916 — developmental biology — Posted on 2017-11-15

850 Systematic analysis of the molecular architecture of endocytosis reveals a nanoscale actin nucleation template that drives efficient vesicle formation

Mund, M.; van der Beek, J. A.; Deschamps, J.; Dmitrieff, S.; Monster, J. L.; Picco, A.; Nedelec, F.; Kaksonen, M.; Ries, J.

10.1101/217836 — cell biology — Posted on 2017-11-15

851 The SCWISh network is essential for survival under mechanical pressure.

Delarue, M.; Poterewicz, G.; Hoxha, O.; Choi, J.; Yoo, W.; Kayser, J.; Holt, L.; Hallatschek, O.

10.1101/150789 — cell biology — Posted on 2017-11-15

852 Combining optical imaging of cleared tissue with mathematical modelling to predict drug delivery and therapeutic response

d'Esposito, A.; Sweeney, P.; Ali, M.; Saleh, M.; Ramasawmy, R.; Roberts, T. A.; Desjardins, A.; Lythgoe, M. F.; Pedley, R. B.; Shipley, R.; Walker-Samuel, S.

10.1101/219865 — biophysics — Posted on 2017-11-15

853 Powerful Inference with the D-statistic on Low-Coverage Whole-Genome Data

Soraggi, S.; Wiuf, C.; Albrechtsen, A.

10.1101/127852 — bioinformatics — Posted on 2017-11-15

854 Privacy-preserving generative deep neural networks support clinical data sharing

Beaulieu-Jones, B. K.; Wu, Z. S.; Williams, C.; Byrd, J. B.; Greene, C. S.

10.1101/159756 — bioinformatics — Posted on 2017-11-15

855 Balances: a new perspective for microbiome analysis

Rivera Pinto, J.; Egozcue, J. J.; Pawlowsky-Glahn, V.; Paredes, R.; Noguera-Julian, M.; Calle, M. L.

10.1101/219386 — bioinformatics — Posted on 2017-11-15

856 Simultaneous Determination of Protein Structure and Dynamics Using Cryo-Electron Microscopy

Bonomi, M.; Pellarin, R.; Vendruscolo, M.

10.1101/219972 — bioinformatics — Posted on 2017-11-15

857 The Bio::Phylo libraries for phylogenetic data analysis, version 2.0

Vos, R. A.; Hettling, H.

10.1101/211334 — bioinformatics — Posted on 2017-11-15

858 Molecular characterization of breast and lung tumors by integration of multiple data types with sparse-factor analysis

Bismeijer, T.; Canisius, S.; Wessels, L.

10.1101/183582 — bioinformatics — Posted on 2017-11-15

859 No changes in parieto-occipital alpha during neural phase locking to visual quasi-periodic theta-, alpha-, and beta-band stimulation

Keitel, C.; Benwell, C. S.; Thut, G.; Gross, J.

10.1101/219766 — neuroscience — Posted on 2017-11-15

860 Metaproteomics of colonic microbiota unveils discrete protein functions among colitic mice and control groups

Moon, C.; Stupp, G. S.; Su, A. I.; Wolan, D. W.

10.1101/219782 — bioinformatics — Posted on 2017-11-15

861 BURRITO: An interactive multi-omic tool for visualizing taxa-function relationships in microbiome data

McNally, C. P.; Eng, A.; Noecker, C.; Gagne-Maynard, W. C.; Borenstein, E.

10.1101/217315 — bioinformatics — Posted on 2017-11-15

862 Whole-cell scale dynamic organization of lysosomes revealed by spatial statistical analysis

Ba, Q.; Raghavan, G.; Kiselyov, K.; Yang, G.

10.1101/219790 — systems biology — Posted on 2017-11-14

863 Hox genes pattern the primary body axis of an anthozoan cnidarian prior to gastrulation

DuBuc, T. Q.; Stephenson, T. B.; Rock, A. N.; Martindale, M. Q.

10.1101/219758 — developmental biology — Posted on 2017-11-14

864 Whole-transcriptome causal network inference with genomic and transcriptomic data

Wang, L.; Michoel, T.

10.1101/213371 — systems biology — Posted on 2017-11-14

865 The unrealized potential of herbaria in global change biology

Meineke, E. K.; Davis, C. C.; Davies, T. J.

10.1101/218776 — plant biology — Posted on 2017-11-14

866 Tracking wakefulness as it fades: micro-measures of Alertness

Jagannathan, S. R.; Nassar, A. E.; Jachs, B.; Pustovaya, O. V.; Bareham, C. A.; Bekinschtein, T. A.

10.1101/219527 — neuroscience — Posted on 2017-11-14

867 The Brain Dynamics Toolbox for Matlab

Heitmann, S.; Aburn, M. J.; Breakspear, M.

10.1101/219329 — neuroscience — Posted on 2017-11-14

868 Genetic Single Neuron Anatomy reveals fine granularity of cortical interneuron subtypes

10.1101/219485 — neuroscience — Posted on 2017-11-14

869 A random-dot kinematogram for web-based vision research

Rajananda, S.; Lau, H.; Odegaard, B.

10.1101/192377 — neuroscience — Posted on 2017-11-14

870 Histone deacetylation promotes transcriptional silencing at facultative heterochromatin

Watts, B. R.; Wittmann, S.; Wery, M.; Gautier, C.; Kus, K.; Heo, D.-H.; Kilchert, C.; Morillon, A.; Vasiljeva, L.

10.1101/219535 — molecular biology — Posted on 2017-11-14

871 Rapid, modular, and cost-effective generation of donor DNA constructs for CRISPR-based gene knock-in

Chen, Y.-J.; Wang, W.; Tian, X.-J.; Lefever, D. E.; Taft, D. A.; Xing, J.

10.1101/219618 — molecular biology — Posted on 2017-11-14

872 High-throughput sequencing of murine immunoglobulin heavy chain transcripts using single side unique molecular identifiers on an Ion Torrent PGM

Buerckert, J.-P.; Faison, W. J.; Dubois, A. R. S. X.; Sinner, R.; Hunewald, O.; Wienecke-Baldacchino, A.; Brieger, A.; Muller, C. P.

10.1101/219568 — immunology — Posted on 2017-11-14

873 Quantifying Immune-Based Counterselection of Somatic Mutations

Yang, F.; Kim, D.-K.; Nakagawa, H.; Hayashi, S.; Imoto, S.; Stein, L.; Roth, F.

10.1101/219576 — genetics — Posted on 2017-11-14

874 Smg5 is required for multiple nonsense-mediated mRNA decay pathways in Drosophila

Nelson, J. O.; Foerster, D.; Frizzell, K.; Luschnig, S.; Metzstein, M. M.

10.1101/219725 — genetics — Posted on 2017-11-14

875 Advances in computer-assisted syndrome recognition and differentiation in a set of metabolic disorders

Pantel, J. T.; Zhao, M.; Mensah, M. A.; Hajjir, N.; Hsieh, T.-C.; Hanani, Y.; Fleischer, N.; Kamphans, T.; Mundlos, S.; Gurovich, Y.; Krawitz, P. M.

10.1101/219394 — genetics — Posted on 2017-11-14

876 Causal gene inference by multivariate mediation analysis in Alzheimer's disease

Park, Y.; Sarkar, A.; He, L.; Davilla-Velderrain, J.; De Jager, P. L.; Kellis, M.

10.1101/219428 — genetics — Posted on 2017-11-14

877 Male age is associated with extra-pair paternity, but not with extra-pair mating behaviour

Girndt, A.; Chng, C. W. T.; Burke, T.; Schroeder, J.

10.1101/219477 — evolutionary biology — Posted on 2017-11-14

878 Singleton Variants Dominate the Genetic Architecture of Human Gene Expression

Hernandez, R. D.; Uricchio, L. H.; Hartman, K.; Ye, J.; Dahl, A.; Zaitlen, N.

10.1101/219238 — evolutionary biology — Posted on 2017-11-14

879 Effects of partial selfing on the equilibrium genetic variance, mutation load and inbreeding depression under stabilizing selection

Abu Awad, D.; Roze, D.

10.1101/180000 — evolutionary biology — Posted on 2017-11-14

880 The dynamics of starvation and recovery

Yeakel, J. D.; Kempes, C. P.; Redner, S.

10.1101/219519 — ecology — Posted on 2017-11-14

881 Species abundance plays a dominant role in local and regional extinctions in freshwater communities and allows the identification of selective extinctions

Almeida, R. J.; Biro, E. G.; Woods, L. M.; Smith, K. G.

10.1101/219469 — ecology — Posted on 2017-11-14

882 The Habc Domain of Syntaxin 3 is a Ubiquitin Binding Domain with Specificity for K63-Linked Poly-Ubiquitin Chains

Giovannone, A. J.; Reales, E.; Bhattaram, P.; Nackeeran, S.; Monahan, A. B.; Syed, R.; Weimbs, T.

10.1101/219642 — cell biology — Posted on 2017-11-14

883 Accurate Discrimination of 23 Major Cancer Types via Whole Genome Somatic Mutation Patterns

Jiao, W.; Polak, P.; Karlic, R.; Getz, G.; Stein, L. D.; PCAWG Pathology & Clinical Correlates Working Grp, ; ICGC/TCGA Pan-cancer Analysis of Whole Genomes Net,

10.1101/214494 — cancer biology — Posted on 2017-11-14

884 Modeling Enhancer-Promoter Interactions with Attention-Based Neural Networks

Mao, W.; Kostka, D.; Chikina, M.

10.1101/219667 — bioinformatics — Posted on 2017-11-14

885 COLT-Viz: Interactive Visualization of Antibody Lineage Trees

He, C.; Wendel, B. S.; Xiao, J.; Chen, K.; Jiang, N.

10.1101/219592 — bioinformatics — Posted on 2017-11-14

886 Automated high throughput animal DNA metabarcode classification

Porter, T. M.; Hajibabaei, M.

10.1101/219675 — bioinformatics — Posted on 2017-11-14

887 Complementary, High-throughput Methods for Creating Multi-dimensional, PEG-based Biomaterials

Brooks, E. A.; Jansen, L. E.; Gencoglu, M. F.; Yurkevicz, A. M.; Peyton, S.

10.1101/219501 — bioengineering — Posted on 2017-11-14

888 Structure and function of accessory Sec proteins involved in the adhesin export pathway of Streptococcus gordonii

Chen, Y.; Bensing, B. A.; Seepersaud, R.; Mi, W.; Liao, M.; Jeffrey, P. D.; Shajahan, A.; Sonon, R. N.; Azadi, P.; Sullam, P. M.; Rapoport, T. A.

10.1101/219105 — biochemistry — Posted on 2017-11-14

889 Evidence of non-tandemly repeated rDNAs and their intragenomic heterogeneity in Rhizophagus irregularis

Maeda, T.; Kobayashi, Y.; Kameoka, H.; Okuma, N.; Takeda, N.; Yamaguchi, K.; Bino, T.; Shigenobu, S.; Kawaguchi, M.

10.1101/205864 — plant biology — Posted on 2017-11-14

890 Beyond Bilingualism: multilingual experience correlates with caudate volume

Hervais-Adelman, A.; Egorova, N.; Golestani, N.

10.1101/209619 — neuroscience — Posted on 2017-11-14

891 Divergent effects of healthy ageing on semantic knowledge and control: Evidence from novel comparisons with semantically-impaired patients

Hoffman, P.

10.1101/216192 — neuroscience — Posted on 2017-11-14

892 Heterogeneous Responses of Hematopoietic Stem Cells to Inflammatory Stimuli are Altered with Age

Mann, M.; Mehta, A.; de Boer, C.; Kowalczyk, M. S.; Lee, K.; Rogel, N.; Knecht, A. R.; Farouq, D.; Regev, A.; Baltimore, D.

10.1101/163402 — immunology — Posted on 2017-11-14

893 Expanding heterochromatin reveals discrete subtelomeric domains delimited by chromatin landscape transitions

Hocher, A.; Ruault, M.; Kaferle, P.; Garnier, M.; Descrimes, M.; Morillon, A.; Taddei, A.

10.1101/187138 — genomics — Posted on 2017-11-14

894 Scaling accurate genetic variant discovery to tens of thousands of samples

Poplin, R.; Ruano-Rubio, V.; DePristo, M. A.; Fennell, T. J.; Carneiro, M. O.; Van der Auwera, G. A.; Kling, D. E.; Gauthier, L. D.; Levy-Moonshine, A.; Roazen, D.; Shakir, K.; Thibault, J.; Chandran, S.; Whelan, C.; Lek, M.; Gabriel, S.; Daly, M. J.; Neale, B.; MacArthur, D. G.; Banks, E.

10.1101/201178 — genomics — Posted on 2017-11-14

895 Systemic Markers of Adaptive and Innate Immunity Are Associated with COPD Severity and Spirometric Disease Progression

Halper-Stromberg, E.; Yun, J. H.; Parker, M. M.; Tal-Singer, R. M.; Gaggar, A.; Silverman, E. K.; Leach, S.; Bowler, R. P.; Castaldi, P. J.

10.1101/193920 — genomics — Posted on 2017-11-14

896 Quantifying the contribution of recessive coding variation to developmental disorders

Martin, H. C.; Jones, W. D.; Stephenson, J.; Handsaker, J.; Gallone, G.; McRae, J. F.; Prigmore, E.; Short, P.; Niemi, M.; Kaplanis, J.; Radford, E.; Akawi, N.; Balasubramanian, M.; Dean, J.; Horton, R.; Hulbert, A.; Johnson, D. S.; Johnson, K.; Kumar, D.; Lynch, S. A.; Mehta, S. G.; Morton, J.; Parker, M. J.; Splitt, M.; Turnpenny, P. D.; Vasudevan, P. C.; Wright, M.; Wright, C. F.; FitzPatrick, D. R.; Firth, H. V.; Hurles, M. E.; Barrett, J. C.

10.1101/201533 — genetics — Posted on 2017-11-14

897 Quantifying the impact of rare and ultra-rare coding variation across the phenotypic spectrum

Ganna, A.; Satterstrom, K.; Zekavat, S.; Das, I.; Kurki, M.; Churchhouse, C.; Alfoldi, J.; Martin, A.; Havulinna, A.; Byrnes, A.; Thompson, W.; Nielsen, P.; Karczewski, K.; Saarentaus, E.; Rivas, M.; Gupta, N.; Pietilainen, O.; Emdin, C.; Lescai, F.; Bybjerg-Grauholm, J.; Flannick, J.; Mercader, J.; Udler, M.; Laakso, M.; Salomaa, V.; Hultman, C.; Ripatti, S.; Hamalainen, E.; Moilanen, J.; Korkko, J.; Kuismin, O.; Nordentoft, M.; Hougaard, D.; Mors, O.; Werge, T.; Mortensen, P.; MacArthur, D.; Daly, M.; Sullivan, P.; Locke, A.; Palotie, A.; Borglum, A.; Kathiresan, S.; Neale, B.

10.1101/148247 — genetics — Posted on 2017-11-14

898 Evidence for convergent evolution of host parasitic manipulation in response to environmental conditions

Loreto, R. G.; Araujo, J. P. M.; Kepler, R. M.; Fleming, K. R.; Moreau, C. S.; Hughes, D. P.

10.1101/211144 — evolutionary biology — Posted on 2017-11-14

899 On Model Averaging Partial Regression Coefficients

Walker, J. A.

10.1101/133785 — ecology — Posted on 2017-11-14

900 Consensus and conflict among ecological forecasts of Zika virus outbreaks in the United States

Carlson, C. J.; Dougherty, E.; Boots, M.; Getz, W.; Ryan, S.

10.1101/138396 — ecology — Posted on 2017-11-14

901 Cobwebbing in the city: urbanization-driven changes in web-building are decoupled from body size in an orb-web spider

Dahirel, M.; De Cock, M.; Vantieghem, P.; Bonte, D.

10.1101/214924 — ecology — Posted on 2017-11-14

902 Theory of site-specific DNA-protein interactions in the presence of nucleosome roadblocks

Murugan, R.

10.1101/214387 — biophysics — Posted on 2017-11-14

903 QuASAR: Quality Assessment of Spatial Arrangement Reproducibility in Hi-C Data

Sauria, M. E.; Taylor, J.

10.1101/204438 — bioinformatics — Posted on 2017-11-14

904 High genomic diversity of multi-drug resistant wastewater Escherichia coli

Mahfouz, N.; Caucci, S.; Achatz, E.; Semmler, T.; Guenther, S.; Berendonk, T.; Schroeder, M.

10.1101/215210 — bioinformatics — Posted on 2017-11-14

905 3D label-free imaging and analysis of Pinus pollen grains using optical diffraction tomography

Kim, G.; Lee, S.; Shin, S.; Park, Y.

10.1101/219378 — plant biology — Posted on 2017-11-14

906 What drives results in Bayesian morphological clock analyses?

Parins-Fukuchi, C.; Brown, J. W.

10.1101/219048 — paleontology — Posted on 2017-11-14

907 Advanced Lesion Symptom Mapping Analyses And Implementation As BCBtoolkit

Foulon, C.; Cerliani, L.; Kinkingnehun, S.; Levy, R.; Rosso, C.; Urbanski, M.; Volle, E.; Thiebaut de Schotten, M.

10.1101/133314 — neuroscience — Posted on 2017-11-14

908 Hyperedge bundling: A practical solution to spurious interactions in MEG/EEG source connectivity analyses

Wang, S. H.; Lobier, M.; Siebenhuhner, F.; Palva, S.; Palva, J. M.

10.1101/219311 — neuroscience — Posted on 2017-11-14

909 Peak gamma frequency and cortical laminar processing are modified across the healthy menstrual cycle

Sumner, R. L.; McMillan, R. L.; Shaw, A. D.; Singh, K. D.; Sundram, F.; Muthukumaraswamy, S.

10.1101/219196 — neuroscience — Posted on 2017-11-14

910 A proof-of-principle study of the effect of combined haloperidol and levodopa administration on working memory-related brain activation in humans

van Ruitenbeek, P.; Hernaus, D.; Mehta, M. A.

10.1101/219436 — neuroscience — Posted on 2017-11-14

911 Physiological Gaussian Process Priors for the Hemodynamics in fMRI Analysis

Wilzen, J.; Eklund, A.; Villani, M.

10.1101/179838 — neuroscience — Posted on 2017-11-14

912 Mutations in C11ORF70 cause primary ciliary dyskinesia with randomization of left/right body asymmetry due to outer and inner dynein arm defects

Höben, I. M.; Hjeij, R.; Olbrich, H.; Dougherty, G. W.; Menchen, T.; Aprea, I.; Frank, D.; Pennekamp, P.; Dworniczak, B.; Wallmeier, J.; Raidt, J.; Nielsen, K. G.; Philipsen, M. C.; Santamaria, F.; Venditto, L.; Amirav, I.; Prenzel, F.; Wu, K.; Schmidts, M.; Loges, N. T.; Omran, H.

10.1101/218206 — molecular biology — Posted on 2017-11-14

913 Potent and Selective Antitumor Activity of a T-Cell Engaging Bispecific Antibody Targeting a Membrane-Proximal Epitope of ROR1

Qi, J.; Li, X.; Peng, H.; Park, H.; Rader, C.

10.1101/219402 — immunology — Posted on 2017-11-14

914 Reduced cellular diversity and an altered basal progenitor cell state inform epithelial barrier dysfunction in human type 2 immunity

Ordovas-Montanes, J.; Dwyer, D. F.; Nyquist, S. K.; Buchheit, K. M.; Deb, C.; Wadsworth, M. H.; Hughes, T. K.; Kazer, S. W.; Yoshimoto, E.; Bhattacharyya, N.; Katz, H. R.; Laidlaw, T. M.; Boyce, J. A.; Barrett, N. A.; Shalek, A. K.

10.1101/218958 — immunology — Posted on 2017-11-14

915 T helper cells modulate intestinal stem cell renewal and differentiation

Biton, M.; Haber, A.; Beyaz, S.; Rogel, N.; Smillie, C.; Shekhar, K.; Schnell, A.; Chen, Z.; Wu, C.; Ordovas-Montanes, J.; Alvarez, D.; Herbst, R. H.; Tirosh, I.; Burgin, G.; Dionne, D.; Xifaras, M. E.; Zhang, M.; Shalek, A. K.; von Andrian, U. H.; Graham, D. B.; Rozenblatt-Rosen, O.; Shi, H. N.; Kuchroo, V.; Yilmaz, O.; Regev, A.; Xavier, R. J.

10.1101/217133 — immunology — Posted on 2017-11-14

916 Genome-wide analyses of self-reported empathy: correlations with autism, schizophrenia, and anorexia nervosa

Warrier, V.; Toro, R.; Chakrabarti, B.; iPSYCH-Broad Autism Group, ; Borglum, A. D.; Grove, J.; 23andMe Research Team, ; Hinds, D.; Bourgeron, T.; Baron-Cohen, S.

10.1101/050682 — genomics — Posted on 2017-11-14

917 Independent assessment and improvement of wheat genome assemblies using Fosill jumping libraries

Lu, F.-H.; McKenzie, N.; Kettleborough, G.; Heavens, D.; Clark, M. D.; Bevan, M. W.

10.1101/219352 — genomics — Posted on 2017-11-14

918 Cross-species systems analyses reveal a conserved brain transcriptional response to social challenge

Saul, M. C.; Blatti, C.; Yang, W.; Bukhari, S. A.; Shpigler, H. Y.; Troy, J. M.; Seward, C. H.; Sloofman, L. G.; Chandrasekaran, S.; Bell, A. M.; Stubbs, L. J.; Robinson, G. E.; Zhao, S. D.; Sinha, S.

10.1101/219444 — genomics — Posted on 2017-11-14

919 Scaling accurate genetic variant discovery to tens of thousands of samples

10.1101/201178 — genomics — Posted on 2017-11-14

920 Genetic risk for neurodegenerative disorders, and its overlap with cognitive ability and physical function

Hagenaars, S.; Radakovic, R.; Crockford, C.; Fawns-Ritchie, C.; International FTD-Genomics Consortium, ; Harris, S. E.; Gale, C. R.; Deary, I. J.

10.1101/219345 — genetics — Posted on 2017-11-14

921 Combined flow cytometry and high throughput image analysis for the study of essential genes in Caenorhabditis elegans

Hernando-Rodriguez, B.; Erinjeri, A. P.; Rodriguez-Palero, M. J.; Millar, V.; Gonzalez-Hernandez, S.; Olmedo, M.; Schulze, B.; Baumeister, R.; Munoz, M. J.; Askjaer, P.; Artal-Sanz, M.

10.1101/218735 — genetics — Posted on 2017-11-14

922 The function of the prereplicative complex and SCF complex components during Drosophila wing development

Kohzaki, H.

10.1101/219220 — genetics — Posted on 2017-11-14

923 The nature of nurture: effects of parental genotypes

Kong, A.; Thorleifsson, G.; Frigge, M. L.; Vilhjalmsson, B.; Young, A. I.; Thorgeirsson, T. E.; Benonisdottir, S.; Oddsson, A.; Halldorsson, B. V.; Masson, G.; Gudbjartsson, D. F.; Helgason, A.; Bjornsdottir, G.; Thorsteinsdottir, U.; Stefansson, K.

10.1101/219261 — genetics — Posted on 2017-11-14

924 Estimating heritability without environmental bias

Young, A. I.; Frigge, M. L.; Gudbjartsson, D. F.; Thorleifsson, G.; Bjornsdottir, G.; Sulem, P.; Masson, G.; Thorsteinsdottir, U.; Stefansson, K.; Kong, A.

10.1101/218883 — genetics — Posted on 2017-11-14

925 Developmental constraints on genome evolution in four bilaterian model species

Liu, J.; Robinson-Rechavi, M.

10.1101/161679 — evolutionary biology — Posted on 2017-11-14

926 The necessary emergence of structural complexity in self-replicating RNA populations.

G. Oliver, C.; Reinharz, V.; Waldispühl, J.

10.1101/218990 — evolutionary biology — Posted on 2017-11-14

927 Gene regulatory network architecture in different developmental contexts influences the genetic basis of morphological evolution

Kittelmann, S.; Buffry, A. D.; Almudi, I.; Yoth, M.; Sabaris, G.; Franke, F. A.; Couso, J. P.; Nunes, M. D. S.; Frankel, N.; Gomez-Skarmeta, J. L.; Pueyo-Marques, J.; Arif, S.; McGregor, A. P.

10.1101/219337 — evolutionary biology — Posted on 2017-11-14

928 An epithelial-mesenchymal-amoeboid transition gene signature reveals molecular subtypes of breast cancer progression and metastasis

Emad, A.; Ray, T.; Jensen, T. W.; Parat, M.; Natrajan, R.; Sinha, S.; Ray, P. S.

10.1101/219410 — cancer biology — Posted on 2017-11-14

929 Discrete and continuum approximations for collective cell migration in a scratch assay with cell size dynamics

Matsiaka, O. M.; Penington, C.; Baker, R. E.; Simpson, M.

10.1101/219204 — biophysics — Posted on 2017-11-14

930 DNA sequence encodes the position of DNA supercoils

Kim, S. H.; Ganji, M.; Torre, J. v. d.; Abbondanzieri, E.; Dekker, C.

10.1101/180414 — biophysics — Posted on 2017-11-14

931 Combining RNA-seq data and homology-based gene prediction for plants, animals and fungi

Keilwagen, J.; Hartung, F.; Paulini, M.; Twardziok, S. O.; Grau, J.

10.1101/219287 — bioinformatics — Posted on 2017-11-14

932 A systems approach to refine disease taxonomy by integrating phenotypic and molecular networks

Zhou, X.; Lei, L.; Liu, J.; Halu, A.; Zhang, Y.; Li, B.; Guo, Z.; Liu, G.; Sun, C.; Loscalzo, J.; Sharma, A.; Wang, Z.

10.1101/219089 — bioinformatics — Posted on 2017-11-14

933 Genomes from uncultivated prokaryotes: a comparison of metagenome-assembled and single-amplified genomes

Alneberg, J.; Karlsson, C. M. G.; Divne, A.-M.; Bergin, C.; Homa, F.; Lindh, M. V.; Hugerth, L. W.; Ettema, T. J. G.; Bertilsson, S.; Andersson, A. F.; Pinhassi, J.

10.1101/219295 — bioinformatics — Posted on 2017-11-14

934 Beyond pseudotime: Following T-cell maturation in single-cell RNAseq time series

Fischer, D. S.; Fiedler, A. K.; Kernfeld, E.; Genga, R. M. J.; Hasenauer, J.; Maehr, R.; Theis, F. J.

10.1101/219188 — bioinformatics — Posted on 2017-11-14

935 Large protein complex production using the SmartBac System - Strategies and Applications

Zhai, Y.; Zhang, D.; Yu, L.; Sun, F.; Sun, F.

10.1101/219246 — bioengineering — Posted on 2017-11-14

936 Hospitalizations associated with respiratory syncytial virus (RSV) and influenza in children, including children having a diagnosis of asthma

Goldstein, E.

10.1101/161067 — epidemiology — Posted on 2017-11-13

937 New routes for PTP1B allosteric inhibition by multitemperature crystallography, fragment screening and covalent tethering

Keedy, D. A.; Hill, Z. B.; Biel, J. T.; Kang, E.; Rettenmaier, T. J.; Brandao-Neto, J.; Pearce, N. M.; von Delft, F.; Wells, J. A.; Fraser, J. S.

10.1101/218966 — biophysics — Posted on 2017-11-13

938 Bringing Diffuse X-ray Scattering Into Focus

Wall, M.; Wolff, A. M.; Fraser, J. S.

10.1101/219113 — biophysics — Posted on 2017-11-13

939 AQMM: Enabling Absolute Quantification of Metagenome and Metatranscriptome

Jiang, X.-T.; Yu, K.; Li, L.-G.; Yin, X. L.; Li, A. D.; Zhang, T.

10.1101/218347 — bioinformatics — Posted on 2017-11-13

940 A Deep Recurrent Neural Network Discovers Complex Biological Rules to Decipher RNA Protein-Coding Potential

Hill, S. T.; Kuintzle, R. C.; Teegarden, A.; Merrill, E.; Danaee, P.; Hendrix, D. A.

10.1101/200758 — bioinformatics — Posted on 2017-11-13

941 sigQC: A procedural approach for standardising the evaluation of gene signatures

Dhawan, A.; Barberis, A.; Cheng, W.-C.; Domingo, E.; West, C.; Maughan, T.; Scott, J.; Harris, A. L.; Buffa, F. M.

10.1101/203729 — bioinformatics — Posted on 2017-11-13

942 CODEX2: full-spectrum copy number variation detection by high-throughput DNA sequencing

Jiang, Y.; Anastopoulos, I. N.; Nathanson, K. L.; Zhang, N. R.

10.1101/211698 — bioinformatics — Posted on 2017-11-13

943 A Deep Recurrent Neural Network Discovers Complex Biological Rules to Decipher RNA Protein-Coding Potential

Hill, S. T.; Kuintzle, R. C.; Teegarden, A.; Merrill, E.; Danaee, P.; Hendrix, D. A.

10.1101/200758 — bioinformatics — Posted on 2017-11-13

944 A hyperthermophilic phage decoration protein suggests common evolutionary origin with Herpesvirus Triplex proteins and an anti-CRISPR protein

Stone, N. P.; Hilbert, B. J.; Hidalgo, D.; Halloran, K. T.; Kelch, B. A.

10.1101/216911 — biochemistry — Posted on 2017-11-13

945 A new sequencing-based women’s health assay combining self-sampling, HPV detection and genotyping, STI detection, and vaginal microbiome analysis

Bik, E. M.; Bird, S. W.; Bustamante, J. P.; Leon, L. E.; Nieto, P. A.; Addae, K.; Alegria-Mera, V.; Bravo, C.; Bravo, D.; Cardenas, J. P.; Caughey, A.; Covarrubias, P. C.; Perez-Donoso, J.; Gass, G.; Gupta, S. L.; Harman, K.; Hongo, D. M. B.; Jimenez, J. C.; Kraal, L.; Melis-Arcos, F.; Morales, E. H.; Morton, A.; Navas, C. F.; Nunez, H.; Olivares, E.; Ordenes-Aenishanslins, N.; Ossandon, F. J.; Phan, R.; Pino, R.; Soto-Liebe, K.; Varas, I.; Walton, N. A.; Vera-Wolf, P.; Almonacid, D. E.; Goddard, A. D.; Ugalde, J. A.; Richman, J.; Apte, Z. S.

10.1101/217216 — microbiology — Posted on 2017-11-13

946 The CD11a and EPCR marker combination simplifies and improves the purification of mouse hematopoietic stem cells

Karimzadeh, A.; Scarfone, V.; Chao, C.; Grathwohl, K.; Fathman, J. W.; Fruman, D.; Serwold, T.; Inlay, M.

10.1101/219063 — immunology — Posted on 2017-11-13

947 LINE-2 transposable elements shape post-transcriptional gene regulation in the human brain

Petri, R.; Brattas, P. L.; Jönsson, M. E.; Pircs, K.; Bengzon, J.; Jakobsson, J.

10.1101/218842 — genomics — Posted on 2017-11-13

948 Protein structures as shapes: Analysing protein structure variation using geometric morphometrics

Hleap, J. S.; Blouin, C.

10.1101/219030 — bioinformatics — Posted on 2017-11-13

949 DNA Damage Induced Chromosomal Instability. Computational modeling view.

Eidelman, Y.; Slanina, S.; Pyatenko, V.; Andreev, S.

10.1101/218826 — systems biology — Posted on 2017-11-13

950 Towards a unified resource for transcriptional regulation in Escherichia coli K-12: Incorporating high throughput-generated binding data within the classic framework of regulation of initiation of transcription in RegulonDB.

Santos-Zavaleta, A.; Sanchez-Perez, M.; Salgado, H.; Velazquez-Ramirez, D. A.; Gama-Castro, S.; Tierrafria, V. H.; Busby, S.; Fang, X.; Palsson, B.; Galagan, J.; Collado-Vides, J.

10.1101/219006 — systems biology — Posted on 2017-11-13

951 Viral Complexity: Amino acid co-evolution in viral genomes as a possible metric

Sruthi, C. K.; Prakash, M. K.

10.1101/159541 — systems biology — Posted on 2017-11-13

952 Explanation implies causation?

Myint, L.; Leek, J. T.; Jager, L. R.

10.1101/218784 — scientific communication and education — Posted on 2017-11-13

953 Bin-Free Fitting of Probability Distributions Emphasizing DNA Histograms

Rochman, N. D.

10.1101/218933 — scientific communication and education — Posted on 2017-11-13

954 How Changes in Common Practice Can Improve the Quality of Biomedical Science

Steinfath, M.; Vogl, S.; Violet, N.; Schwarz, F.; Mielke, H.; Selhorst, T.; Greiner, M.; Schoenfelder, G.

10.1101/218867 — scientific communication and education — Posted on 2017-11-13

955 Intestinal crypts recover rapidly from focal damage with coordinated motion of stem cells that is impaired by aging

Choi, J.; Rakhilin, N.; Gadamsetty, P.; Joe, D. J.; Tabrizian, T.; Lipkin, S. M.; Huffman, D.; Shen, X.; Nishimura, N.

10.1101/218685 — physiology — Posted on 2017-11-13

956 Detecting pathogen exposure during the non-symptomatic incubation period using physiological data

Milechin, L.; Davis, S.; Patel, T.; Hernandez, M.; Ciccarelli, G.; Schwartz, S.; Samsi, S.; Hensley, L.; Goff, A.; Trefry, J.; Johnston, S.; Purcell, B.; Cabrera, C.; Fleischman, J.; Reuther, A.; Rossi, F.; Honko, A.; Pratt, W.; Swiston, A.

10.1101/218818 — physiology — Posted on 2017-11-13

957 PGC-1β prevents statin-associated myotoxicity in oxidative skeletal muscle

Singh, F.; Zoll, J.; Duthaler, U.; Charles, A.-L.; Laverny, G.; Metzger, D.; Geny, B.; Kraehenbuehl, S.; Bouitbir, J.

10.1101/218636 — pharmacology and toxicology — Posted on 2017-11-13

958 Age-dependent neurodegeneration and organelle transport deficiencies in mutant TDP43 patient-derived neurons are independent of TDP43 aggregation

Kreiter, N.; Pal, A.; Lojewski, X.; Corcia, P.; Naujock, M.; Reinhardt, P.; Sterneckert, J.; Petri, S.; Wegner, F.; Storch, A.; Hermann, A.

10.1101/218610 — neuroscience — Posted on 2017-11-13

959 Online detection of auditory attention with mobile EEG: closing the loop with neurofeedback

Zink, R.; Proesmans, S.; Bertrand, A.; Van Huffel, S.; De Vos, M.

10.1101/218727 — neuroscience — Posted on 2017-11-13

960 Acute fluoxetine differently affects aggressive display in zebrafish phenotypes

Barbosa, H. P.; Lima, M. G.; Maximino, C.

10.1101/217810 — neuroscience — Posted on 2017-11-13

961 Striatal action-value neurons reconsidered

Elber-Dorozko, L.; Loewenstein, Y.

10.1101/087502 — neuroscience — Posted on 2017-11-13

962 The Drosophila dystonia gene homolog Neurocalcin facilitates sleep by inhibiting a movement-promoting neural network

Chen, K.-F.; Lamaze, A.; Kratschmer, P.; Jepson, J. E. C.

10.1101/159772 — neuroscience — Posted on 2017-11-13

963 Hierarchy of transcriptomic specialization across human cortex captured by myelin map topography

Burt, J. B.; Demirtas, M.; Eckner, W. J.; Navejar, N. M.; Ji, J. L.; Martin, W. J.; Bernacchia, A.; Anticevic, A.; Murray, J. D.

10.1101/199703 — neuroscience — Posted on 2017-11-13

964 Impaired perceptual learning in Fragile X syndrome is mediated by parvalbumin neuron dysfunction in V1 and is reversible.

Goel, A.; Cantu, D.; Guilfoyle, J.; Chaudhari, G. R.; Newadkar, A.; Todisco, B.; Alba, D. d.; Kourdougli, N.; Schmitt, L. M.; Pedapati, E.; Erickson, C. A.; Portera-Cailliau, C.

10.1101/217414 — neuroscience — Posted on 2017-11-13

965 Regulation of vocal precision by local noradrenergic modulation of a motor nucleus

Schmidt, M. F.; Glaze, C. M.; Castelino, C. B.; Bibu, S. P.; Yau, E.

10.1101/218479 — neuroscience — Posted on 2017-11-13

966 Limitations of proposed signatures of Bayesian confidence

Adler, W. T.; Ma, W. J.

10.1101/218222 — neuroscience — Posted on 2017-11-13

967 Is dopamine D1 receptor availability related to social behavior? A positron emission tomography replication study

Plaven-Sigray, P.; Matheson, G. J.; Gustavsson, P.; Stenkrona, P.; Halldin, C.; Farde, L.; Cervenka, S.

10.1101/218420 — neuroscience — Posted on 2017-11-13

968 Brca2, Pds5 and Wapl differentially control cohesin chromosome association and function

Misulovin, Z.; Pherson, M.; Gause, M.; Dorsett, D.

10.1101/170829 — molecular biology — Posted on 2017-11-13

969 CHRAC/ACF Contribute to the Repressive Ground State of Chromatin

Scacchetti, A.; Brueckner, L.; Jain, D.; Schauer, T.; Zhang, X.; Schnorrer, F.; van Steensel, B.; Straub, T.; Becker, P. B.

10.1101/218768 — molecular biology — Posted on 2017-11-13

970 MapZ forms a stable ring structure that acts as a track for FtsZ treadmilling in Streptococcus mutans

Li, Y.; Shao, S.; Xu, X.; Su, X.; Sun, Y.; Wei, S.

10.1101/218677 — microbiology — Posted on 2017-11-13

971 Antimicrobial resistant Klebsiella pneumoniae carriage and infection in specialized geriatric care wards linked to acquisition in the referring hospital

Gorrie, C. L.; Mirceta, M.; Wick, R. R.; Judd, L. M.; Wyres, K. L.; Thomson, N. R.; Strugnell, R. A.; Pratt, N. F.; Garlick, J. F.; Watson, K. M.; Hunter, P. C.; McGloughlin, S. A.; Spelman, D. W.; Jenney, A. W. J.; Holt, K. E.

10.1101/218461 — microbiology — Posted on 2017-11-13

972 Cyanobacterial Growth on Municipal Wastewater Requires Low Temperatures

Korosh, T. C.; Dutcher, A.; Pfleger, B. F.; McMahon, K.

10.1101/161166 — microbiology — Posted on 2017-11-13

973 Transcriptional landscape and regulatory roles of small non-coding RNAs in the oxidative stress response of the haloarchaeon Haloferax volcanii

Gelsinger, D. R.; DiRuggiero, J.

10.1101/218552 — microbiology — Posted on 2017-11-13

974 Fine scale diversification of endolithic microbial communities in the hyper-arid Atacama Desert

Meslier, V.; Casero, M. C.; Dailey, M.; Wierzchos, J.; Ascaso, C.; Artieda, O.; DiRuggiero, J.

10.1101/218446 — microbiology — Posted on 2017-11-13

975 Fusicatenibacter Is Associated with Kefir Drinking

Sprague, R.

10.1101/218313 — microbiology — Posted on 2017-11-13

976 The study of antibody responses to influenza neuraminidase using a lentiviral pseudotype based ELLA

Biuso, F.; Carnell, G.; Montomoli, E.; Temperton, N. J.

10.1101/218800 — microbiology — Posted on 2017-11-13

977 One-step generation of monoclonal B cell receptor mice capable of class switch recombination and somatic hypermutation

Jacobsen, J. T.; Mesin, L.; Markoulaki, S.; Cavazzoni, C. B.; Bousbaine, D.; Jaenisch, R.; Victora, G. D.

10.1101/218438 — immunology — Posted on 2017-11-13

978 MicroRNA-21 Regulates Metabolic Adaptation of Pathogenic TH17 cells and Controls Autoimmune Inflammation

Yu, X.; Wang, L.; Yao, C.; Qiu, R.; Cui, Y. G.; Dai, D.; Deng, J.; Hou, G. J.; Wang, Y.; Qian, J.; Ou, Y. Y.; Qin, Y. T.; Zhou, H. B.; Qian, Y. C.; Tang, Y. J.; Shen, N.

10.1101/218545 — immunology — Posted on 2017-11-13

979 B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage

Wong, J. B.; Hewitt, S. L.; Heltemes-Harris, L. M.; Mandal, M.; Johnson, K.; Rajewsky, K.; Koralov, S. B.; Clark, M. R.; Farrar, M. A.; Skok, J. A.

10.1101/214908 — immunology — Posted on 2017-11-13

980 Comparing miRNA structure of mirtrons and non-mirtrons

Titov, I. I.; Vorozheykin, P. S.

10.1101/218701 — genomics — Posted on 2017-11-13

981 Easy quantification of template-directed CRISPR/Cas9 editing

Brinkman, E. K.; Nedergaard Kousholt, A.; Harmsen, T.; Leemans, C.; Chen, T.; Jonkers, J.; van Steensel, B.

10.1101/218156 — genetics — Posted on 2017-11-13

982 Characterization of Glycosylphosphatidylinositol Biosynthesis Defects by Clinical Features, Flow Cytometry, and Automated Image Analysis

Knaus, A.; Pantel, J. T.; Pendziwiat, M.; Hajjir, N.; Zhao, M.; Hsieh, T.-C.; Schubach, M.; Gurovich, Y.; Fleischer, N.; Jaeger, M.; Koehler, S.; Muhle, H.; Korff, C.; Moller, R. S.; Bayat, A.; Calvas, P.; Chassaing, N.; Warren, H.; Skinner, S. A.; Louie, R.; Evers, C.; Bohn, M.; Christen, H.-J.; van den Born, M.; Obersztyn, E.; Charzewska, A.; Endziniene, M.; Kortuem, F.; Brown, N.; Robinson, P. N.; Schelhaas, H. J.; Weber, Y.; Helbig, I.; Mundlos, S.; Horn, D.; Krawitz, P. M.

10.1101/216291 — genetics — Posted on 2017-11-13

983 Phenome-wide association studies (PheWAS) across large "real-world data" population cohorts support drug target validation

Diogo, D.; Tian, C.; Franklin, C.; Alanne-Kinnunen, M.; March, M.; Spencer, C.; Vangjeli, C.; Weale, M.; Mattsson, H.; Kilpelainen, E.; Sleiman, P.; Reilly, D.; McElwee, J.; Maranville, J.; Chatterjee, A.; Bhandari, A.; the 23andMe Research Team, ; Reeve, M.-P.; Hutz, J.; Bing, N.; John, S.; MacArthur, D.; Salomaa, V.; Ripatti, S.; Hakonarson, H.; Daly, M.; Palotie, A.; Hinds, D.; Donnelly, P.; Fox, C.; Day-Williams, A.; Plenge, R.; Runz, H.

10.1101/218875 — genetics — Posted on 2017-11-13

984 ADAM17 is the Principal Ectodomain Sheddase of the EGF-Receptor Ligand Amphiregulin

Hosur, V.; Farley, M. L.; Burzenski, L. M.; Shultz, L. D.; Wiles, M. V.

10.1101/218891 — genetics — Posted on 2017-11-13

985 Ant nurse workers exhibit behavioral and transcriptomic specialization on larval stage but not caste

Walsh, J. T.; Warner, M. R.; Kase, A.; Cushing, B. J.; Linksvayer, T. A.

10.1101/218834 — evolutionary biology — Posted on 2017-11-13

986 Epidemiological trade-off between intra- and interannual scales in the evolution of aggressiveness in a local plant pathogen population

Suffert, F.; Goyeau, H.; Sache, I.; Carpentier, F.; Gelisse, S.; Morais, D.; Delestre, G.

10.1101/151068 — epidemiology — Posted on 2017-11-13

987 The Impact of 2017 ACC/AHA Guidelines on the Prevalence of Hypertension and Eligibility for Anti-Hypertensive Therapy in the United States and China

Khera, R.; Lu, Y.; Saxena, A.; Nasir, K.; Krumholz, H. M.

10.1101/218859 — epidemiology — Posted on 2017-11-13

988 The Impact of 2017 ACC/AHA Guidelines on the Prevalence of Hypertension and Eligibility for Anti-Hypertensive Therapy in the United States and China

Khera, R.; Lu, Y.; Saxena, A.; Nasir, K.; Krumholz, H. M.

10.1101/218859 — epidemiology — Posted on 2017-11-13

989 Size-reduced embryos reveal a gradient scaling based mechanism for zebrafish somite formation

Ishimatsu, K.; Hiscock, T. W.; Collins, Z. M.; Sari, D. W. K.; Lischer, K.; Richmond, D. L.; Bessho, Y.; Matsui, T.; Megason, S. G.

10.1101/211615 — developmental biology — Posted on 2017-11-13

990 EpiGraph: an open-source platform to quantify epithelial organization

Vicente-Munuera, P.; Gomez-Galvez, P.; Tagua, A.; Letran, M.; Mao, Y.; Escudero, L. M.

10.1101/217521 — developmental biology — Posted on 2017-11-13

991 Maternal proteins that are phospho-regulated upon egg activation include crucial factors for oogenesis, egg activation and embryogenesis in Drosophila melanogaster

Zhang, Z.; Krauchunas, A. R.; Huang, S.; Wolfner, M. F.

10.1101/218925 — developmental biology — Posted on 2017-11-13

992 The NSIGHT1 Randomized Controlled Trial: Rapid Whole Genome Sequencing for Accelerated Etiologic Diagnosis in Critically Ill Infants

Petrikin, J. E.; Cakici, J. A.; Clark, M.; Willig, L.; Sweeney, N.; Farrow, E.; Saunders, C.; Thiffault, I.; Miller, N.; Zellmer, L.; Herd, S.; Holmes, A.; Batalov, S.; Veeraraghavan, N.; Smith, L.; Dimmock, D.; Leeder, S.; Kingsmore, S. F.

10.1101/218255 — clinical trials — Posted on 2017-11-13

993 CDC20B is required for deuterosome-mediated centriole production in multiciliated cells

Revinski, D. R.; Zaragosi, L.-E.; Boutin, C.; Ruiz-Garcia, S.; Deprez, M.; Rosnet, O.; Thome, V.; Mercey, O.; Paquet, A.; Pons, N.; Marcet, B.; Kodjabachian, L.; Barbry, P.

10.1101/218750 — cell biology — Posted on 2017-11-13

994 Deciphering the histone code to build the genome structure

Prakash, K.; Fournier, D.

10.1101/217190 — cell biology — Posted on 2017-11-13

995 A semi-quantitative analysis of lupus arthritis using contrasted high-field MRI

Zollars, E.; Chapin, R.

10.1101/218503 — biophysics — Posted on 2017-11-13

996 PRS-on-Spark: a novel, efficient and flexible approach for generating polygenic risk scores

Chen, L. M.; Yao, N.; Garg, E.; Zhu, Y.; Nguyen, T. T. T.; Pokhvisneva, I.; Hari Dass, S. A.; Forest, M.; McEwen, L. M.; MacIsaac, J. L.; Kobor, M. S.; Greenwood, C. M. T.; Silveira, P. P.; Meaney, M. J.; O'Donnell, K. J.

10.1101/209833 — bioinformatics — Posted on 2017-11-13

997 TRUmiCount: Correctly counting absolute numbers of molecules using unique molecular identifiers

Pflug, F. G.; von Haeseler, A.

10.1101/217778 — bioinformatics — Posted on 2017-11-13

998 TRUmiCount: Correctly counting absolute numbers of molecules using unique molecular identifiers

Pflug, F. G.; von Haeseler, A.

10.1101/217778 — bioinformatics — Posted on 2017-11-10

999 Clinker: visualising fusion genes detected in RNA-seq data

Schmidt, B. M.; Davidson, N. M.; Hawkins, A. D.; Bartolo, R.; Majewski, I. J.; Ekert, P. G.; Oshlack, A.

10.1101/218586 — bioinformatics — Posted on 2017-11-13

1000 AQMM: Enabling Absolute Quantification of Metagenome and Metatranscriptome

Jiang, X.-T.; Yu, K.; Li, L.-G.; Yin, X. L.; Li, A. D.; Zhang, T.

10.1101/218347 — bioinformatics — Posted on 2017-11-13

1001 BayCount: A Bayesian Decomposition Method for Inferring Tumor Heterogeneity using RNA-Seq Counts

Xie, F.; Zhou, M.; Xu, Y.

10.1101/218511 — bioinformatics — Posted on 2017-11-13

Lithgow-Serrano, O. W.; Gama-Castro, S.; Ishida-Gutierrez, C.; Mejia-Almonte, C.; Tierrafria, V.; Martinez-Luna, S.; Santos-Zavaleta, A.; Velazquez-Ramirez, D.; Collado-Vides, J.

10.1101/219014 — bioinformatics — Posted on 2017-11-13

1003 Structure of transmembrane helix 8 and possible membrane defects in CFTR

Corradi, V.; Gu, R.-X.; Vergani, P.; Tieleman, D. P.

10.1101/218792 — biochemistry — Posted on 2017-11-13

1004 Role of guard-cell ABA in determining maximal stomatal aperture and prompt vapor-pressure-deficit response

Yaaran, A.; Negin, B.; Moshelion, M.

10.1101/218719 — plant biology — Posted on 2017-11-13

1005 The role of telomere shortening in carcinogenesis: A hybrid stochastic-deterministic approach

Rodriguez-Brenes, I. A.; Komarova, N.; Wodarz, D.

10.1101/218537 — cancer biology — Posted on 2017-11-13

1006 Quadratic Programming Data Descriptors for Abnormal Beat Detection in ECG Recordings

Minhas, F. u. A. A.

10.1101/218008 — bioinformatics — Posted on 2017-11-13

1007 Modeling mesoscopic cortical dynamics using a mean-field model of conductance-based networks of adaptive exponential integrate-and-fire neurons

Zerlaut, Y.; Chemla, S.; Chavane, F.; Destexhe, A.

10.1101/168385 — neuroscience — Posted on 2017-11-12

1008 The role of m6A-RNA methylation in stress response regulation

Engel, M.; Roeh, S.; Eggert, C.; Kaplick, P. M.; Tietze, L.; Arloth, J.; Weber, P.; Rex-Haffner, M.; Jakovcevski, M.; Uhr, M.; Eder, M.; Wotjak, C. T.; Schmidt, M. V.; Deussing, J. M.; Binder, E. B.; Chen, A.

10.1101/200402 — neuroscience — Posted on 2017-11-12

1009 Electrophysiological signatures of spatial boundaries in the human subiculum

Lee, S. A.; Miller, J. F.; Watrous, A. J.; Sperling, M.; Sharan, A.; Worrell, G. A.; Berry, B. M.; Jobst, B. C.; Davis, K. A.; Gross, R. E.; Lega, B.; Sheth, S.; Das, S. R.; Stein, J. M.; Gorniak, R.; Rizzuto, D. S.; Jacobs, J.

10.1101/218040 — neuroscience — Posted on 2017-11-12

1010 Heritability Informed Power Optimization (HIPO) Leads to Enhanced Detection of Genetic Associations Across Multiple Traits

Qi, G.; Chatterjee, N.

10.1101/218404 — genetics — Posted on 2017-11-12

1011 Sexual Imprinting And Speciation In Two Peromyscus Species

Delaney, E. K.; Hoekstra, H. E.

10.1101/145243 — evolutionary biology — Posted on 2017-11-12

1012 Early-exposure to new sex pheromone blend alters mate preference in female butterflies and in their offspring

Dion, E.; Pui, L. X.; Monteiro, A.

10.1101/214635 — evolutionary biology — Posted on 2017-11-12

1013 Comparison of fine-scale recombination maps in fungal plant pathogens reveals dynamic recombination landscapes and intragenic hotspots

Stukenbrock, E. H.; Dutheil, J. Y.

10.1101/158907 — evolutionary biology — Posted on 2017-11-12

1014 Electrophysiological signatures of spatial boundaries in the human subiculum

10.1101/218040 — neuroscience — Posted on 2017-11-12

1015 Genetic ablation of RhoA in adult microglia causes synapse and neuronal loss

Socodato, R.; Portugal, C. C.; Canedo, T.; Henriques, J.; Vaz, S. H.; Magalhaes, J. D.; Silva, C. M.; Baptista, F. I.; Alves, R. L.; Nogueira, J.; Coelho-Santos, V.; Silva, A. P.; Paes-de-Carvalho, R.; Magalhaes, A.; Summavielle, T.; Brakebusch, C.; Sebastiao, A. M.; Ambrosio, A. F.; Relvas, J. B.

10.1101/218107 — neuroscience — Posted on 2017-11-12

1016 A theory of multineuronal dimensionality, dynamics and measurement

Gao, P.; Trautmann, E.; Yu, B. M.; Santhanam, G.; Ryu, S.; Shenoy, K.; Ganguli, S.

10.1101/214262 — neuroscience — Posted on 2017-11-12

1017 Dynamics of finely resolved, abundant symbiotic marine plankton and other interacting microbes via automated high-frequency sampling

Needham, D. M.; Fichot, E. B.; Wang, E.; Berdjeb, L.; Cram, J. A.; Fichot, C. G.; Fuhrman, J. A.

10.1101/216978 — microbiology — Posted on 2017-11-12

1018 Transposon insertional mutagenesis in Saccharomyces uvarum reveals trans-acting effects influencing species dependent essential genes

Sanchez, M. R.; Payen, C.; Cheong, F.; Hovde, B.; Bissonnette, S.; Arkin, A.; Skerker, J. M.; Brem, R.; Caudy, A. A.; Dunham, M. J.

10.1101/218305 — genomics — Posted on 2017-11-12

1019 Genetic analysis of de novo variants reveals sex differences in complex and isolated congenital diaphragmatic hernia and indicates MYRF as a candidate gene

Qi, H.; Yu, L.; Zhou, X.; Kitaygorodsky, A.; Wynn, J.; Zhu, N.; Aspelund, G.; Lim, F. Y.; Crombleholme, T.; Cusick, R.; Azarow, K.; Danko, M. E.; Chung, D.; Warner, B. W.; Mychaliska, G. B.; Potoka, D.; Wagner, A. J.; ElFiky, M.; Nickerson, D. A.; Bamshad, M. J.; Wilson, J. M.; High, F. A.; Longoni, M.; Donahoe, P.; Chung, W. K.; Shen, Y.

10.1101/206037 — genetics — Posted on 2017-11-12

1020 Energetic Evolution of Cellular Transportomes

Darbani, B.; Kell, D. B.; Borodina, I.

10.1101/218396 — evolutionary biology — Posted on 2017-11-12

1021 Epidemiological trade-off between intra- and interannual scales in the evolution of aggressiveness in a local plant pathogen population

Suffert, F.; Goyeau, H.; Sache, I.; Carpentier, F.; Gelisse, S.; Morais, D.; Delestre, G.

10.1101/151068 — epidemiology — Posted on 2017-11-12

1022 Robustness of early warning signals for catastrophic and non-catastrophic transitions

Dutta, P. S.; Sharma, Y.; Abbott, K.

10.1101/218297 — ecology — Posted on 2017-11-12

1023 High fidelity lineage tracing in mouse pre-implantation embryos using primed conversion of photoconvertible proteins

Welling, M.; Mohr, M. A.; Ponti, A.; Sabater, L. R.; Boni, A.; Liberali, P.; Pelczar, P.; Pantazis, P.

10.1101/218354 — developmental biology — Posted on 2017-11-12

1024 PPARD regulation in gastric progenitor cells drives gastric tumorigenesis in mice

Zuo, X.; Deguchi, Y.; Xu, W.; Wei, D.; Tian, R.; Chen, W.; Moussalli, M. J.; Liu, Y.; Mao, F.; Xu, M.; Yang, Y.; Gao, S.; Jaoude, J. C.; Liu, F.; Gagea, M.; Broaddus, R.; Xie, K.; Shureiqi, I.

10.1101/218214 — cancer biology — Posted on 2017-11-12

1025 MCO: towards an ontology and unified vocabulary for a framework-based annotation of microbial growth conditions

Tierrafria, V. H.; Mejia-Almonte, C.; Camacho-Zaragoza, J. M.; Salgado, H.; Alquicira, K.; Gama-Castro, S.; Collado-Vides, J.

10.1101/218289 — bioinformatics — Posted on 2017-11-12

1026 Using Optimal F-Measure and Random Resampling in Gene Ontology Enrichment Calculations

Ge, W.; Fazal, Z.; Jakobsson, E.

10.1101/218248 — bioinformatics — Posted on 2017-11-12

1027 Saturating Single-Cell Datasets

Bhaduri, A.; Nowakowski, T. J.; Pollen, A. A.; Kriegstein, A. R.

10.1101/218370 — bioinformatics — Posted on 2017-11-12

1028 The effect of macromolecular crowding on single-round transcription by E. coli RNA polymerase

Chung, S.; Lerner, E.; Jin, Y.; Kim, S.; Alhadid, Y.; Grimaud, L. W.; Zhang, I. X.; Knobler, C. M.; Gelbart, W. M.; Weiss, S.

10.1101/218321 — biochemistry — Posted on 2017-11-12

1029 People Can Create Iconic Vocalizations to Communicate Various Meanings to Naive Listeners

Perlman, M.; Lupyan, G.

10.1101/148841 — animal behavior and cognition — Posted on 2017-11-12

1030 Laccaria bicolor MiSSP8 is a small-secreted protein decisive for the establishment of the ectomycorrhizal symbiosis

Pellegrin, C.; Daguerre, Y.; Ruytinx, J.; Guinet, F.; Kemppainen, M.; Plourde, M. B.; Hecker, A.; Morin, E.; Pardo, A. G.; Germain, H.; Martin, F. M.; Veneault-Fourrey, C.

10.1101/218131 — plant biology — Posted on 2017-11-11

1031 Extra-field spike-timed activity shifts the place field center of mass to encode aversion experience

Mamad, O.; Agayby, B.; Stumpp, L.; Reilly, R. B.; Tsanov, M.

10.1101/218180 — neuroscience — Posted on 2017-11-11

1032 Circuit-based models of shared variability in cortical networks

Huang, C.; Ruff, D.; Pyle, R.; Rosenbaum, R.; Cohen, M.; Doiron, B. D.

10.1101/217976 — neuroscience — Posted on 2017-11-11

1033 Regulation of Eag by calcium/calmodulin controls presynaptic excitability in Drosophila

Bronk, P.; Kuklin, E. A.; Liu, C.; Wiggin, T. D.; Reed, M. L.; Gorur-Shandilya, S.; Marder, E.; Griffith, L. C.

10.1101/215293 — neuroscience — Posted on 2017-11-11

1034 Theta and alpha oscillations are traveling waves in the human neocortex

Zhang, H.; Watrous, A. J.; Patel, A.; Jacobs, J.

10.1101/218198 — neuroscience — Posted on 2017-11-11

1035 Sleep-Dependent Memory Consolidation and Incremental Sentence Comprehension: Computational Dependencies during Language Learning as Revealed by Neuronal Oscillations

Cross, Z. R.; Kohler, M. J.; Schlesewsky, M.; Gaskell, M. G.; Bornkessel-Schlesewsky, I.

10.1101/218123 — neuroscience — Posted on 2017-11-11

1036 White Matter Connectivity Reflects Success in Musical Improvisation

Zeng, T.; Przysinda, E.; Pfeifer, C.; Arkin, C.; Loui, P.

10.1101/218024 — neuroscience — Posted on 2017-11-11

1037 Genome-wide transcriptional responses of iron-starved Chlamydia trachomatis reveal prioritization of metabolic precursor synthesis over protein translation

Brinkworth, A. J.; Wildung, M. R.; Carabeo, R. A.

10.1101/217992 — microbiology — Posted on 2017-11-11

1038 Anti-phage islands force their target phage to directly mediate island excision and spread

McKitterick, A. C.; Seed, K.

10.1101/218164 — microbiology — Posted on 2017-11-11

1039 QTLseqr: An R package for bulk segregant analysis with next-generation sequencing

Mansfeld, B. N.; Grumet, R.

10.1101/208140 — genomics — Posted on 2017-11-11

1040 Role of SCN5A coding and non-coding sequences in Brugada syndrome onset: What’s behind the scenes?

Daimi, H.; Haj Khelil, A.; Neji, A.; Ben Hamda, K.; Maaoui, S.; Aranega, A.; Be Chibani, J.; Franco Jaime, D.

10.1101/218099 — genetics — Posted on 2017-11-11

1041 High genetic loading for schizophrenia predicts poor response to lithium in patients with bipolar disorder: A polygenic score and cross-trait genetic analysis

Amare, A. T.; Schubert, K. O.; The International Consortium on Lithium Genetics, ; Schulze, T. G.; Baune, B.

10.1101/209270 — genetics — Posted on 2017-11-11

1042 Don’t throw out the sympatric species with the crater lake water: fine-scale investigation of introgression provides weak support for functional role of secondary gene flow in one of the clearest examples of sympatric speciation

Richards, E.; Martin, C.; Poelstra, J.

10.1101/217984 — evolutionary biology — Posted on 2017-11-11

1043 An agent-based model of cattle grazing toxic Geyer’s larkspur

Jablonski, K.; Boone, R. B.; Meiman, P. J.

10.1101/218032 — ecology — Posted on 2017-11-11

1044 A synergistic transcriptional regulation of olfactory genes derives complex behavioral responses in the mosquito Anopheles culicifacies

Das De, T.; Thomas, T.; Verma, S.; Singla, D.; Rawal, C.; Srivastava, V.; Sharma, P.; Kumari, S.; Tevatiya, S.; Rani, J.; Hasija, Y.; Pandey, K. C.; Dixit, R.

10.1101/218081 — animal behavior and cognition — Posted on 2017-11-11

1045 The impact of tumor receptor heterogeneity on the response to anti-angiogenic cancer treatment

Li, D.; Finley, S.

10.1101/218073 — systems biology — Posted on 2017-11-11

1046 L-tyrosine supplementation is not therapeutic for skeletal muscle dysfunction in zebrafish and mouse models of dominant skeletal muscle α-actin nemaline myopathy.

Messineo, A. M.; Gineste, C.; Sztal, T. E.; McNamara, E. L.; Vilmen, C.; Ogier, A. C.; Hahne, D.; Bendahan, D.; Laing, N. G.; Bryson-Richardson, R. J.; Gondin, J.; Nowak, K. J.

10.1101/218016 — neuroscience — Posted on 2017-11-11

1047 Local network-level integration mediates effects of transcranial Alternating Current Stimulation

Fusca, M.; Ruhnau, P.; Neuling, T.; Weisz, N.

10.1101/216176 — neuroscience — Posted on 2017-11-11

1048 Covalent linkage of the DNA repair template to the CRISPR/Cas9 complex enhances homology-directed repair

Savic, N.; Ringnalda, F.; Bargsten, K.; Li, Y.; Berk, C.; Hall, J.; Neri, D.; Jinek, M.; Schwank, G.

10.1101/218149 — molecular biology — Posted on 2017-11-11

1049 Phytophthora methylomes modulated by expanded 6mA methyltransferases are associated with adaptive genome regions

Chen, H.; Shu, H.; Wang, L.; Zhang, F.; Li, X.; Ochola, S.; Mao, F.; Ma, H.; Ye, W.; Gu, T.; Jiang, L.; Wu, Y.; Wang, Y.; Kamoun, S.; Dong, S.

10.1101/217646 — molecular biology — Posted on 2017-11-11

1050 Polymerase pausing induced by sequence-specific RNA binding protein drives heterochromatin assembly

Parsa, J.-Y.; Boudoukha, S.; Burke, J.; Homer, C.; Madhani, H.

10.1101/217968 — molecular biology — Posted on 2017-11-11

1051 Maintaining tiger connectivity and minimizing extinction into the next century: Insights from landscape genetics and spatially-explicit simulations

Thatte, P.; Joshi, A.; Vaidyanathan, S.; Landguth, E.; Ramakrishnan, U.

10.1101/081117 — genetics — Posted on 2017-11-11

1052 Functional redundancy of variant and canonical histone H3 lysine 9 modification in Drosophila

Penke, T. J. R.; McKay, D. J.; Strahl, B. D.; Matera, A. G.; Duronio, R. J.

10.1101/183251 — genetics — Posted on 2017-11-11

1053 Can Ebola Virus evolve to be less virulent in humans?

Sofonea, M. T.; Aldakak, L.; Boullosa, L. F. V. V.; Alizon, S.

10.1101/108589 — evolutionary biology — Posted on 2017-11-11

1054 Targeting the Untargetable: Predicting Pramlintide Resistance Using a Neural Network Based Cellular Automata

Kim, E.; Schenck, R.; West, J.; Cross, W.; Harris, V.; McKenna, J.; Cho, H.; Coker, E.; Lee-Kramer, S.; Tsai, K.; Flores, E.; Gatenbee, C. D.

10.1101/211383 — cancer biology — Posted on 2017-11-11

1055 FateID infers cell fate bias in multipotent progenitors from single-cell RNA-seq data

Herman, J. S.; Sagar, S.; Grun, D.

10.1101/218115 — bioinformatics — Posted on 2017-11-11

1056 A mid-level organization of the ventral stream

Long, B.; Yu, C.-P.; Konkle, T.

10.1101/213934 — neuroscience — Posted on 2017-11-10

1057 Adaptation in a fibronectin binding autolysin of Staphylococcus saprophyticus

Mortimer, T. D.; Annis, D. S.; O'Neill, M. B.; Bohr, L. L.; Smith, T. M.; Poinar, H. N.; Mosher, D. F.; Pepperell, C. S.

10.1101/136556 — microbiology — Posted on 2017-11-10

1058 Nuclear Abl Drives Extracellular-Vesicle Transfer of miR-34c to Induce Bystander Effects of Radiation

Rastogi, S.; Hwang, A.; Chan, J.; Wang, J. Y.

10.1101/209767 — cell biology — Posted on 2017-11-10

1059 Microbial community structure corresponds to nutrient gradients and human impact within coastal wetlands of the Great Lakes.

Horton, D. J.; Theis, K. R.; Uzarski, D. G.; Learman, D. R.

10.1101/217919 — microbiology — Posted on 2017-11-10

1060 Hospitalized premature infants are colonized by related bacterial strains with distinct proteomic profiles

Brown, C. T.; Xiong, W.; Olm, M. R.; Thomas, B. C.; Baker, R.; Firek, B.; Morowitz, M. J.; Hettich, R. L.; Banfield, J. F.

10.1101/217950 — microbiology — Posted on 2017-11-10

1061 Mitochondrial genomes of the regionally extinct Nittany Lion (Puma concolor from Pennsylvania)

Evanitsky, M. N.; George, R. J.; Johnson, S.; Dowell, S.; Perry, G. H.

10.1101/214510 — ecology — Posted on 2017-11-10

1062 A repetitive mutation and selection system for bacterial evolution to increase the specific affinity to pancreatic cancer cells.

Osawa, M.

10.1101/217893 — cancer biology — Posted on 2017-11-10

1063 Within-host dynamics explain the coexistence of antibiotic-sensitive and resistant bacteria

Davies, N. G.; Flasche, S.; Jit, M.; Atkins, K. E.

10.1101/217232 — epidemiology — Posted on 2017-11-10

1064 Bayesian estimation of MSM population size in Côte d’Ivoire

Datta, A.; Lin, W.; Rao, A.; Diouf, D.; Kouame, A.; Edwards, J. K.; Bao, L.; Louis, T. A.; Baral, S.

10.1101/213926 — epidemiology — Posted on 2017-11-10

1065 Integrative construction of regulatory region networks in 127 human reference epigenomes by matrix factorization

Liu, D.; Davila-Velderrain, J.; Zhang, Z.; Kellis, M.

10.1101/217588 — epidemiology — Posted on 2017-11-10

1066 Mesoscale turbulence in the hippocampus

Sheremet, A.; Qin, Y.; Kennedy, J. P.; Maurer, A.

10.1101/217877 — neuroscience — Posted on 2017-11-10

1067 The role of sensorimotor variability and computation in falls in the elderly

Lin, C.-H.; Faisal, A.

10.1101/196584 — neuroscience — Posted on 2017-11-10

1068 Use-dependent plasticity in human primary motor hand area:Synergistic interplay between training and immobilisation

Raffin, E.; Siebner, H. R.

10.1101/217661 — neuroscience — Posted on 2017-11-10

1069 Failure of in vitro differentiation of Plasmodium falciparum gametocytes into ookinetes arises because of poor gamete fertilisation

Delves, M. J.; Marques, S. R.; Ruecker, A.; Straschil, U.; Miguel-Blance, C.; Lopez-Barragan, M. J.; Lelievre, J.; Molina, I.; Wree, M.; Okitsu, S. L.; Winzeler, E.; Li, F.; Vinetz, J.; Sheppard, S.; Guedes, J.; Guerra, N.; Herreros, E.; Sinden, R. E.; Baum, J.

10.1101/216721 — microbiology — Posted on 2017-11-10

1070 Tn5Prime, a Tn5 based 5’ Capture Method for Single Cell RNA-seq

Cole, C.; Byrne, A.; Beaudin, A. E.; Forsberg, E. C.; Vollmers, C.

10.1101/217117 — genomics — Posted on 2017-11-10

1071 Natural genetic variation in C. elegans reveals genomic loci controlling metabolite levels

Gao, A.; Sterken, M.; uit de Bos, J.; Van Creij, J.; Kamble, R.; Snoek, B.; Kammenga, J.; Houtkooper, R. H.

10.1101/217729 — genomics — Posted on 2017-11-10

1072 A genome-wide association study finds novel genetic associations with broadly-defined headache in UK Biobank (N = 223,773)

Meng, W.; Adams, M.; Hebert, H.; Deary, I.; McIntosh, A.; Smith, B.

10.1101/217786 — genetics — Posted on 2017-11-10

1073 Overlooked polyploidies in lycophytes generalize their roles during the evolution of vascular plants

Wang, J.; Yu, J.; Sun, P.; Li, C.; Song, X.; Lei, T.; Li, Y.; Yuan, J.; Sun, S.; Ding, H.; Duan, X.; Shen, S.; Shen, Y.; Li, J.; Meng, F.; Xie, Y.; Wang, J.; Hou, Y.; Zhang, J.; Zhang, X.; Wang, X.

10.1101/217463 — evolutionary biology — Posted on 2017-11-10

1074 Hepatitis C Virus (HCV) diagnosis, epidemiology and access to treatment in a UK cohort

Adland, E.; Jesuthasan, G.; Downs, L.; Wharton, V.; Wilde, G.; McNaughton, A.; Collier, J.; Barnes, E.; Klenerman, P.; Andersson, M.; Jeffery, K.; Matthews, P.

10.1101/216937 — epidemiology — Posted on 2017-11-10

1075 Dynamics of human telomerase recruitment depend on template-telomere base-pairing

Schmidt, J. C.; Zaug, A. J.; Kufer, R.; Cech, T. R.

10.1101/217885 — cell biology — Posted on 2017-11-10

1076 Adaptive dynamics of unstable cancer populations: the canonical equation

Aguade, G.; Sole, R.

10.1101/217851 — cancer biology — Posted on 2017-11-10

1077 The Generalized Data Model for Clinical Research

Danese, M. D.; Halperin, M.; Duryea, J.; Duryea, R.

10.1101/194597 — bioinformatics — Posted on 2017-11-10

1078 Accelerating Evolutionary Hill Climbs in Parallel Turbidostats

Takahashi, C. N.; Zaman, L.; Klavins, E.

10.1101/217273 — synthetic biology — Posted on 2017-11-10

1079 Presence of Atopy Increases the Risk of Asthma Relapse

Teoh, L.; Mackay, I. M.; Van Asperen, P. P.; Acworth, J.; Hurwitz, M.; Upham, J. W.; Siew, W. H.; Wang, C. Y. T.; Sloots, T. P.; Neeman, T.; Chang, A. B.

10.1101/217547 — physiology — Posted on 2017-11-10

1080 Decoding the auditory brain with canonical component analysis

de Cheveigne, A.; Wong, D.; Di Liberto, G.; Hjortkjaer, J.; Slaney, M.; Lalor, E.

10.1101/217281 — neuroscience — Posted on 2017-11-10

1081 Stomach-brain synchrony binds neural representations of the body in a novel, delayed-connectivity resting-state network

Rebollo, I.; Devauchelle, A.-D.; Beranger, B.; Tallon-Baudry, C.

10.1101/217604 — neuroscience — Posted on 2017-11-10

1082 Recurrent network model for learning goal-directed sequences through reverse replay

Haga, T.; Fukai, T.

10.1101/217422 — neuroscience — Posted on 2017-11-10

1083 Neural code subserving feed-forward inhibition in a collision detection circuit

Wang, H.; Dewell, R. B.; Zhu, Y.; Gabbiani, F.

10.1101/217430 — neuroscience — Posted on 2017-11-10

1084 Rapid high-resolution measurement of DNA replication timing by droplet digital PCR

Batrakou, D. G.; Heron, E. D.; Nieduszynski, C. A.

10.1101/208546 — molecular biology — Posted on 2017-11-10

1085 Modified antibiotic adjuvant ratios can slow and steer the evolution of resistance: co-amoxiclav as a case study

Allen, R. C.; Brown, S. P.

10.1101/217711 — microbiology — Posted on 2017-11-10

1086 Chemotaxis allows bacteria to overcome host-generated reactive oxygen species that constrain gland colonization

Collins, K. D.; Hu, S.; Grasberger, H.; Kao, J. Y.; Ottemann, K. M.

10.1101/216515 — microbiology — Posted on 2017-11-10

1087 Epigenomic variation across a polyploid wheat diversity collection

Gardiner, L.-J.; Joynson, R.; Omony, J.; Rusholme-Pilcher, R.; Olohan, L.; Lang, D.; Bai, C.; Hawkesford, M.; Salt, D.; Spannagl, M.; Mayer, K.; Kenny, J.; Bevan, M.; Hall, N.; Hall, A.

10.1101/217828 — genomics — Posted on 2017-11-10

1088 Analysis of ancient human mitochondrial DNA from Verteba Cave, Ukraine: insights into the origins and expansions of the Late Neolithic-Chalcolithic Cututeni-Tripolye Culture

Wakabayashi, K.; Schmidt, R.; Gakuhari, T.; Koganebuchi, K.; Ogawa, M.; Karsten, J.; Sokhatsky, M.; Oota, H.

10.1101/217109 — evolutionary biology — Posted on 2017-11-10

1089 Eco-evolutionary dynamics under limited dispersal: ecological inheritance, altruism within and spite between species

Lehmann, L.; Mullon, C.

10.1101/217570 — evolutionary biology — Posted on 2017-11-10

1090 Breaking the spell of nestedness

Payrato Borras, C.; Hernandez, L.; Moreno, Y.

10.1101/216564 — ecology — Posted on 2017-11-10

1091 Unequal contributions of species’ persistence and migration on plant communities’ response to climate warming throughout forests

Bertrand, R.

10.1101/217497 — ecology — Posted on 2017-11-10

1092 An engineered cellular Timer for analysing the time domain of cellular differentiation in vivo

Bending, D.; Prieto Martin, P.; Paduraru, A.; Marzaganov, E.; Laviron, M.; Kitano, S.; Miyachi, H.; Crompton, T.; Ono, M.

10.1101/217687 — cell biology — Posted on 2017-11-10

1093 Realistic vOlumetric-Approach to Simulate Transcranial Electric Stimulation -- ROAST -- a fully automated open-source pipeline

Huang, Y.; Datta, A.; Bikson, M.; Parra, L. C.

10.1101/217331 — biophysics — Posted on 2017-11-10

1094 Deep2Full: Predictive model for complementing phenotypic outcomes in a deep mutational scan using protein sequence and structure information

Sruthi, C. K.; Prakash, M. K.

10.1101/217158 — bioinformatics — Posted on 2017-11-10

1095 MODE-TASK: Large-scale protein motion tools

Ross, C.; Nizami, B.; Glenister, M.; Sheik Amamuddy, O.; Atilgan, A. R.; Atilgan, C.; Tastan Bishop, O.

10.1101/217505 — bioinformatics — Posted on 2017-11-10

1096 Predicting Transcription Factor Binding Sites with Convolutional Kernel Networks

Chen, D.; Jacob, L.; Mairal, J.

10.1101/217257 — bioinformatics — Posted on 2017-11-10

1097 Multi-Omics factor analysis disentangles heterogeneity in blood cancer

Argelaguet, R.; Velten, B.; Arnol, D.; Dietrich, S.; Zenz, T.; Marioni, J. C.; Buettner, F.; Huber, W.; Stegle, O.

10.1101/217554 — bioinformatics — Posted on 2017-11-10

1098 Minerva: An Alignment and Reference Free Approach to Deconvolve Linked-Reads for Metagenomics

Danko, D. C.; Meleshko, D.; Bezdan, D.; Mason, C.; Hajirasouliha, I.

10.1101/217869 — bioinformatics — Posted on 2017-11-10

1099 Mining the forest: uncovering biological mechanisms by interpreting Random Forests

de Ruiter, J.; Knijnenburg, T.; de Ridder, J.

10.1101/217695 — bioinformatics — Posted on 2017-11-10

1100 Efficient and accurate detection of splice junctions from RNAseq with Portcullis

Mapleson, D.; Venturini, L.; Kaithakottil, G.; Swarbreck, D.

10.1101/217620 — bioinformatics — Posted on 2017-11-10

1101 The Block Object Storage Service (bossDB): A Cloud-Native Approach for Petascale Neuroscience Discovery

Kleissas, D.; Hider, R.; Pryor, D.; Gion, T.; Manavalan, P.; Matelsky, J.; Baden, A.; Lillaney, K.; Burns, R.; D'Angelo, D.; Gray Roncal, W.; Wester, B.

10.1101/217745 — bioinformatics — Posted on 2017-11-10

1102 Mantis: A Fast, Small, and Exact Large-Scale Sequence Search Index

Pandey, P.; Almodaresi, F.; Bender, M. A.; Ferdman, M.; Johnson, R.; Patro, R.

10.1101/217372 — bioinformatics — Posted on 2017-11-10

1103 A substrate for modular, extensible data-visualization

Matelsky, J. K.; Downs, J.; Wester, B.; Gray Roncal, W.

10.1101/217349 — bioinformatics — Posted on 2017-11-10

1104 Diversification of heart progenitor cells by EGF signaling and differential modulation of ETS protein activity

Schwarz, B.; Hollfelder, D.; Scharf, K.; Hartmann, L.; Reim, I.

10.1101/217679 — developmental biology — Posted on 2017-11-10

1105 Deep Residual Network Reveals a Nested Hierarchy of Distributed Cortical Representation for Visual Categorization

Wen, H.; Shi, J.; Chen, W.; Liu, Z.

10.1101/151142 — neuroscience — Posted on 2017-11-10

1106 Improving the calling of non-invasive prenatal testing on 13-/18-/21-trisomy by support vector machine discrimination

Yang, J.; Ding, X.; Zhu, W.

10.1101/216689 — bioinformatics — Posted on 2017-11-10

1107 Uncovering cell-free protein expression dynamics by a promoter library with diverse strengths

Galinanes Reyes, S.; Kuruma, Y.; Tsuda, S.

10.1101/214593 — synthetic biology — Posted on 2017-11-10

1108 Prefrontal D1 dopamine-receptor neurons and delta resonance in interval timing

Kim, Y.-C.; Narayanan, N.

10.1101/216473 — neuroscience — Posted on 2017-11-10

1109 Needle in a haystack? A comparison of eDNA metabarcoding and targeted qPCR for detection of great crested newt (Triturus cristatus)

Harper, L. R.; Lawson Handley, L.; Hahn, C.; Boonham, N.; Rees, H. C.; Gough, K. C.; Lewis, E.; Adams, I. P.; Brotherton, P.; Phillips, S.; Haenfling, B.

10.1101/215897 — molecular biology — Posted on 2017-11-10

1110 In the absence of apoptosis, myeloid cells arrest when deprived of growth factor, but remain viable without ATG5-dependent autophagy or uptake of glucose or glutamine

Dong, L.; Reljic, B.; Lindqvist, L. M.; Vaux, D. L.; Tran, H.

10.1101/198754 — cell biology — Posted on 2017-11-10

1111 Programming of macrophages by apoptotic cancer cells inhibits cancer progression through exosomal PTEN and PPARγ ligands

Kim, Y.-B.; Ahn, Y.-H.; Lee, J.-H.; Kang, J. L.

10.1101/217562 — cancer biology — Posted on 2017-11-10

1112 A tangled tale of convergence and divergence: archaeal chromosomal proteins and Chromo-like domains in bacteria and eukaryotes

Kaur, G.; Iyer, L. M.; Subramanian, S.; Aravind, L.

10.1101/217323 — bioinformatics — Posted on 2017-11-10

1113 Ennet: construction of potential cancer-driving networks based on somatic enhancer mutations only

Cui, Y.; Niu, Y.; Teng, X.; Wang, D.; Luo, H.; Zhang, P.; Wu, W.; He, S.; Luo, J.; Chen, R.

10.1101/216226 — bioinformatics — Posted on 2017-11-10

1114 Neotrygon indica sp. nov., the Indian-Ocean blue-spotted maskray (Myliobatoidei, Dasyatidae)

Pavan-Kumar, A.; Kumar, R.; Pitale, P.; Shen, K.-N.; Borsa, P.

10.1101/179911 — zoology — Posted on 2017-11-10

1115 A scalable method for parameter-free simulation and validation of mechanistic cellular signal transduction network models

Romers, J. C.; Thieme, S.; Muenzner, U.; Krantz, M.

10.1101/107235 — systems biology — Posted on 2017-11-10

1116 Fractone bulbs derive from ependymal cells and their laminin composition influence the stem cell niche in the subventricular zone

Nascimento, M. A.; Sorokin, L.; Coelho-Sampaio, T.

10.1101/093351 — neuroscience — Posted on 2017-11-10

1117 Cross-laboratory analysis of brain cell type transcriptomes with applications to interpretation of bulk tissue data

Mancarci, B. O.; Toker, L.; Tripathy, S. J.; Li, B.; Rocco, B.; Sibille, E.; Pavlidis, P.

10.1101/089219 — neuroscience — Posted on 2017-11-10

1118 Predicting drug resistance evolution: insights from antimicrobial peptides and antibiotics

Yu, G.; Baeder, D.; Regoes, R.; Rolff, J.

10.1101/138107 — evolutionary biology — Posted on 2017-11-10

1119 netDx: Interpretable patient classification using integrated patient similarity networks

Pai, S.; Hui, S.; Isserlin, R.; Shah, M. A.; Kaka, H.; Bader, G. D.

10.1101/084418 — bioinformatics — Posted on 2017-11-10

1120 Automatic sorting system for large calcium imaging data

Takekawa, T.; Asai, H.; Ohkawa, N.; Nomoto, M.; Okubo-Suzuki, R.; Ghandour, K.; Sato, M.; Hayashi, Y.; Inokuchi, K.; Fukai, T.

10.1101/215145 — neuroscience — Posted on 2017-11-09

1121 A heterochromatin domain forms gradually at a new telomere and is highly dynamic at stable telomeres

Wang, J.; Eisenstatt, J. R.; Audry, J.; Cornelius, K.; Shaughnessy, M.; Berkner, K. L.; Runge, K. W.

10.1101/211565 — genetics — Posted on 2017-11-09

1122 Transposable Element Expression Predicts Prognosis in Acute Myeloid Leukemia

Colombo, A. R.; Triche, T.; Ramsingh, G.

10.1101/217299 — cancer biology — Posted on 2017-11-09

1123 Processive movement of actin by biased polymerization: a new paradigm of axonal transport

Chakrabarty, N.; Dubey, P.; Tang, Y.; Ganguly, A.; Ladt, K.; Leterrier, C.; Jung, P.; Roy, S.

10.1101/212449 — neuroscience — Posted on 2017-11-09

1124 Three dimensional cross-modal image inference: label-free methods for subcellular structure prediction

Ounkomol, C.; Fernandes, D. A.; Seshamani, S.; Maleckar, M. M.; Collman, F.; Johnson, G. R.

10.1101/216606 — cell biology — Posted on 2017-11-09

1125 Caloric restriction mitigates age-associated hippocampal differential CG and non-CG methylation.

Hadad, N.; Unnikrishnan, A.; Jackson, J. A.; Masser, D. R.; Otalora, L.; Stanford, D. R.; Richardson, A.; Freeman, W.

10.1101/175810 — neuroscience — Posted on 2017-11-09

1126 Determining the genetic basis of anthracycline-cardiotoxicity by molecular response QTL mapping in induced cardiomyocytes

Knowles, D. A.; Burrows, C. K.; Blischak, J. D.; Patterson, K. M.; Ober, C.; Pritchard, J. K.; Gilad, Y.

10.1101/212381 — genomics — Posted on 2017-11-09

1127 A Cell Type-Specific Class of Chromatin Loops Anchored at Large DNA Methylation Nadirs

Jeong, M.; Huang, X.; Zhang, X.; Su, J.; Shamim, M.; Bochkov, I.; Reyes, J.; Jung, H.; Heikamp, E.; Presser Aiden, A.; Li, W.; Aiden, E.; Goodell, M. A.

10.1101/212928 — genomics — Posted on 2017-11-09

1128 Which line to follow? The utility of different line-fitting methods to capture the mechanism of morphological scaling

Shingleton, A. W.

10.1101/216960 — evolutionary biology — Posted on 2017-11-09

1129 Adaptive evolution within the gut microbiome of individual people

Zhao, S.; Lieberman, T. D.; Poyet, M.; Groussin, M.; Gibbons, S. M.; Xavier, R. J.; Alm, E. J.

10.1101/208009 — evolutionary biology — Posted on 2017-11-09

1130 The cost of enforcing marine protected areas to achieve ecological targets

Brown, C.; Parker, B.; Ahmadia, G. N.; Ardiwijaya, R.; Purwanto, P.; Game, E. T.

10.1101/216598 — ecology — Posted on 2017-11-09

1131 Three dimensional cross-modal image inference: label-free methods for subcellular structure prediction

Ounkomol, C.; Fernandes, D. A.; Seshamani, S.; Maleckar, M. M.; Collman, F.; Johnson, G. R.

10.1101/216606 — cell biology — Posted on 2017-11-09

1132 Optical crosstalk in SPAD arrays for high-throughput single-molecule fluorescence spectroscopy

Ingargiola, A.; Segal, M.; Gulinatti, A.; Rech, I.; Labanca, I.; Maccagnani, P.; Ghioni, M.; Weiss, S.; Michalet, X.

10.1101/207118 — biophysics — Posted on 2017-11-09

1133 Simulation Enabled Search for Explanatory Mechanisms of the Fracture Healing Process

Kennedy, R. C.; Marmor, M.; Marcucio, R.; Hunt, C. A.

10.1101/216523 — physiology — Posted on 2017-11-09

1134 A Model Mechanism Based Explanation of an In Vitro-In Vivo Disconnect for Improving Extrapolation and Translation

Smith, A. K.; Xu, Y.; Ropella, G. E. P.; Hunt, C. A.

10.1101/216556 — pharmacology and toxicology — Posted on 2017-11-09

1135 Aquaporin-4 dependent glymphatic solute transport in rodent brain

Mestre, H.; Kress, B. T.; Zou, W.; Pu, T.; Murlidharan, G.; Castellanos Rivera, R. M.; Simon, M. J.; Pike, M. M.; Plog, B. A.; Xavier, A. L. R.; Thrane, A. S.; Lundgaard, I.; Thomas, J. H.; Xiao, M.; Asokan, A.; Iliff, J. J.; Nedergaard, M.

10.1101/216499 — neuroscience — Posted on 2017-11-09

1136 Muscarinic Lateral Excitation Contributes to Visual Object Segmentation during Collision Avoidance

Zhu, Y.; Dewell, R. B.; Wang, H.; Gabbiani, F.

10.1101/216945 — neuroscience — Posted on 2017-11-09

1137 Contributions of different prefrontal cortical regions to abstract rule acquisition and reversal in monkeys

La Camera, G.; Bouret, S.; Richmond, B. J.

10.1101/180893 — neuroscience — Posted on 2017-11-09

1138 Differential polarization of cortical pyramidal neuron dendrites through weak extracellular fields

Aspart, F.; Remme, M. W. H.; Obermayer, K.

10.1101/216184 — neuroscience — Posted on 2017-11-09

1139 STIMULUS: Noninvasive Dynamic Patterns of Neurostimulation using Spatio-Temporal Interference

Cao, J.; Grover, P.

10.1101/216622 — neuroscience — Posted on 2017-11-09

1140 MACS - a new SPM toolbox for model assessment, comparison and selection

Soch, J.; Allefeld, C.

10.1101/194365 — neuroscience — Posted on 2017-11-09

1141 Is whole-brain functional connectivity a neuromarker of sustained attention? Comment on Rosenberg & al. (2016)

Kristensen, S. B.; Sandberg, K.

10.1101/216697 — neuroscience — Posted on 2017-11-09

1142 The affinity of the S9.6 antibody for double-stranded RNAs impacts the mapping of R-loops in fission yeast.

Hartono, S. R.; Malapert, A.; Legros, P.; Bernard, P.; Chedin, F.; Vanoosthuyse, V.

10.1101/217083 — molecular biology — Posted on 2017-11-09

1143 Structural basis for terminal loop recognition and processing of pri-miRNA-18a by hnRNP A1

Kooshapur, H.; Choudhury, N. R.; Simon, B.; Muehlbauer, M.; Jussupow, A.; Fernandez, N.; Dallmann, A.; Gabel, F.; Camilloni, C.; Michlewski, G.; Caceres, J. F.; Sattler, M.

10.1101/178855 — molecular biology — Posted on 2017-11-09

1144 Differential and defective expression of Koala Retrovirus reveal complexity of host and virus evolution

Tarlinton, R. E.; Sarker, N.; Fabijan, J.; Dottorini, T.; Woolford, L.; Meers, J.; Simmons, G.; Owen, H.; Seddon, J.; Hemmatzedah, F.; Trott, D.; Speight, N.; Emes, R.

10.1101/211466 — microbiology — Posted on 2017-11-09

1145 Cyclic-di-adenosine monophosphate (c-di-AMP) is required for osmotic regulation in Staphylococcus aureus but dispensable for viability in anaerobic conditions

Zeden, M. S.; Schuster, C. F.; Bowman, L.; Zhong, Q.; Grundling, A.

10.1101/216887 — microbiology — Posted on 2017-11-09

1146 Promyelocytic Leukemia (PML) Nuclear Bodies (NBs) Induce Latent/Quiescent HSV-1 Genomes Chromatinization Through a PML-NB/Histone H3.3/H3.3 Chaperone Axis

Cohen, C.; Corpet, A.; Maroui, M. A.; Binda, O.; Poccardi, N.; Rousseau, A.; Texier, P.; Sawtell, N.; Labetoulle, M.; Lomonte, P.

10.1101/217026 — microbiology — Posted on 2017-11-09

1147 Microbiome-by-ethanol interactions impact Drosophila melanogaster fitness and physiology

Chandler, J. A.; Innocent, L. V.; Yang, J. L.; Eisen, M. B.; Ludington, W. B.

10.1101/217240 — microbiology — Posted on 2017-11-09

1148 A modular transcriptional signature identifies phenotypic heterogeneity of human tuberculosis infection

Singhania, A.; Verma, R.; Graham, C. M.; Lee, J.; Trang, T.; Richarsdon, M.; Lecine, P.; Leissner, P.; Berry, M. P. R.; Wilkinson, R. J.; Kaiser, K.; Rodrigue, M.; Woltmann, G.; Haldar, P.; O'Garra, A.

10.1101/216879 — immunology — Posted on 2017-11-09

1149 Association between the brain-derived neurotrophic factor Val66Met polymorphism and overweight/obesity in Mexican pediatric population

Martinez-Ezquerro, J. D.; Rendon-Macias, M. E.; Zamora-Mendoza, G.; Serrano-Meneses, J.; Arellano-Pineda, Y.; Rosales-Rodriguez, B.; Escalante-Bautista, D.; Rodriguez-Cruz, M.; Sanchez Gonzalez, R.; Lopez-Alarcon, M.; Zampedri, M. C.; Rosas-Vargas, H.

10.1101/215798 — genetics — Posted on 2017-11-09

1150 Testing for co-adaptation of plants and arbuscular mycorrhizal fungi in a biodiversity experiment

Hahl, T.; van Moorsel, S. J.; Schmid, M. W.; Zuppinger-Dingley, D.; Schmid, B.; Wagg, C.

10.1101/216986 — ecology — Posted on 2017-11-09

1151 Study mortality with hazard rates, not probabilities

Ergon, T.; Borgan, O.; Nater, C. R.; Vindenes, Y.

10.1101/216739 — ecology — Posted on 2017-11-09

1152 FLIM-based pH measurements reveal incretin-induced rejuvenation of aged insulin secretory granules.

Neukam, M.; Soenmez, A.; Solimena, M.

10.1101/174391 — cell biology — Posted on 2017-11-09

1153 A Cautionary Tail: Changes in Integrin Behavior with Labeling

Galbraith, C. G.; Davidson, M. W.; Galbraith, J. A.

10.1101/158618 — cell biology — Posted on 2017-11-09

1154 The Neutrophil-to-Lymphocyte Ratio as a Prognostic Indicator in Head and Neck Cancer: A Systematic Review and Meta-Analysis

Tham, T.; Bardash, Y.; Herman, W.; Costantino, P.

10.1101/217034 — cancer biology — Posted on 2017-11-09

1155 Venous Thromboembolism Risk in Head and Neck Cancer: Significance of the Preoperative Platelet-to-Lymphocyte Ratio

Tham, T.; Rahman, L.; Persaud, C.; Costantino, P.

10.1101/217042 — cancer biology — Posted on 2017-11-09

1156 Tumorcode - A framework to simulate vascularized tumors

Fredrich, T.; Welter, M.; Rieger, H.

10.1101/216903 — biophysics — Posted on 2017-11-09

1157 Simultaneously measuring image features and resolution in live-cell STED images

Barentine, A. E. S.; Schroeder, L. K.; Graff, M.; Baddeley, D.; Bewersdorf, J.

10.1101/190652 — biophysics — Posted on 2017-11-09

1158 Leveraging multiple transcriptome assembly methods for improved gene structure annotation

Venturini, L.; Caim, S.; Kaithakottil, G.; Mapleson, D. L.; Swarbreck, D.

10.1101/216994 — bioinformatics — Posted on 2017-11-09

1159 SgTiler: a fast method to design tiling sgRNAs for CRISPR/Cas9 mediated screening

Ahmed, M.; He, H. H.

10.1101/217166 — bioinformatics — Posted on 2017-11-09

1160 MRIQC Web-API: Crowdsourcing image quality metrics and expert quality ratings of structural and functional MRI

Esteban, O.; Blair, R. W.; Nielson, D.; Varada, J.; Marrett, S.; Thomas, A.; Poldrack, R.; Gorgolewski, K. J.

10.1101/216671 — bioinformatics — Posted on 2017-11-09

1161 Stringency of synthetic promoter sequences in Clostridium revealed and circumvented by tuning promoter library mutation rates

Mordaka, P. M.; Heap, J. T.

10.1101/216853 — synthetic biology — Posted on 2017-11-09

1162 A Cell Type-Specific Class of Chromatin Loops Anchored at Large DNA Methylation Nadirs

Joeng, M.; Huang, X.; Zhang, X.; Su, J.; Shamim, M.; Bochkov, I.; Reyes, J.; Jung, H.; Heikamp, E.; Presser Aiden, A.; Li, W.; Lieberman Aiden, E.; Goodell, M.

10.1101/212928 — genomics — Posted on 2017-11-09

1163 DNA methylation estimation using methylation-sensitive restriction enzyme bisulfite sequencing (MREBS)

Bonora, G.; Rubbi, L.; Morselli, M.; Chronis, C.; Plath, K.; Pellegrini, M.

10.1101/217208 — genomics — Posted on 2017-11-09

1164 The elephant in the room- Universal coverage for Costly treatments in an upper middle income country

Kaur, R.; Ho, G.; Mastura, M.; Goh, P.; Salowi, M. A.; Radzi, M.; Hau, A.; Sathar, J.; Zambahari, R.; Selladurai, B.; Suleiman, A. B.; Morad, Z.; Ahmad, G.; Lim, T. O.

10.1101/214296 — epidemiology — Posted on 2017-11-09

1165 Glutathione levels influence chronological life span of Saccharomyces cerevisiae in a glucose-dependent manner

Tello-Padilla, M. F.; Perez-Gonzalez, A. Y.; Canizal-Garcia, M.; Gonzalez-Hernandez, J. C.; Cortes-Rojo, C.; Olivares-Marin, I. K.; Madrigal-Perez, L. A.

10.1101/217125 — biochemistry — Posted on 2017-11-09

1166 A hyperthermophilic phage decoration protein suggests common evolutionary origin with Herpesvirus Triplex proteins and an anti-CRISPR protein

Stone, N. P.; Hilbert, B. J.; Hidalgo, D.; Halloran, K. T.; Kelch, B. A.

10.1101/216911 — biochemistry — Posted on 2017-11-09

1167 A primitive starfish ancestor from the Early Ordovician of Morocco reveals the origin of crown group Echinodermata

Hunter, A. W.; Ortega-Hernandez, J.

10.1101/216101 — paleontology — Posted on 2017-11-09

1168 Efficient CRISPR/Cas-mediated homologous recombination in the model diatom Thalassiosira pseudonana

Belshaw, N.; Grouneva, I.; Aram, L.; Gal, A.; Hopes, A.; Mock, T.

10.1101/215582 — molecular biology — Posted on 2017-11-09

1169 Structure of the eukaryotic cytoplasmic pre-40S ribosomal subunit

Scaiola, A.; Pena, C.; Weisser, M.; Boehringer, D.; Leibundgut, M.; Klingauf-Nerurkar, P.; Gerhardy, S.; Panse, V.; Ban, N.

10.1101/216713 — molecular biology — Posted on 2017-11-09

1170 The distance decay of similarity in tropical rainforests. A spatial point processes analytical formulation

Tovo, A.; Favretti, M.

10.1101/216929 — ecology — Posted on 2017-11-09

1171 Promoter activity buffering reduces the fitness cost of misregulation

Schikora-Tamarit, M. A.; Lopez-Grado i Salinas, G.; Gonzalez Navasa, C.; Calderon, I.; Sas, M.; Carey, L.

10.1101/215186 — systems biology — Posted on 2017-11-09

1172 Planetary-wide organization of human cognition

Coutrot, A.; Silva, R.; Manley, E.; de Cothi, W.; Sami, S.; Bohbot, V.; Wiener, J.; Hölscher, C.; Dalton, R. C.; Hornberger, M.; Spiers, H.

10.1101/188870 — neuroscience — Posted on 2017-11-09

1173 PHENOS: a high-throughput and flexible tool for microorganism growth phenotyping on solid media

Barton, D. B. H.; Georghiou, D.; Dave, N.; Alghamdi, M.; Walsh, T.; Louis, E. J.; Foster, S. S.

10.1101/195784 — microbiology — Posted on 2017-11-09

1174 Finite-sample genome-wide regression p-values (GWRPV) with a non-normally distributed phenotype

Connor, G.; O'Neill, M.

10.1101/204727 — genomics — Posted on 2017-11-09

1175 Timescales of influenza A/H3N2 antibody dynamics

Kucharski, A.; Lessler, J.; Cummings, D.; Riley, S.

10.1101/183111 — epidemiology — Posted on 2017-11-09

1176 Generation of Mouse-Zebrafish Hematopoietic Tissue Chimeric Embryos for Hematopoiesis and Host-Pathogen Interaction Studies

Parada-Kusz, M. M.; Clatworthy, A.; Hagedorn, E. J.; Penaranda, C.; Nair, A. V.; Henninger, J. E.; Ernst, C.; Li, B.; Riquelme, R.; Jijon, H.; Villablanca, E. J.; Zon, L. I.; Hung, D.; Allende, M.

10.1101/216895 — developmental biology — Posted on 2017-11-09

1177 Three dimensional cross-modal image inference: label-free methods for subcellular structure prediction

Ounkomol, C.; Fernandes, D. A.; Seshamani, S.; Maleckar, M. M.; Collman, F.; Johnson, G. R.

10.1101/216606 — cell biology — Posted on 2017-11-09

1178 FLIM-based pH measurements reveal incretin-induced rejuvenation of aged insulin secretory granules.

Neukam, M.; Soenmez, A.; Solimena, M.

10.1101/174391 — cell biology — Posted on 2017-11-09

1179 The unconventional kinetoplastid kinetochore protein KKT4 tracks with dynamic microtubule tips

Llauro, A.; Hayashi, H.; Bailey, M. E.; Wilson, A.; Ludzia, P.; Asbury, C. L.; Akiyoshi, B.

10.1101/216812 — cell biology — Posted on 2017-11-09

1180 TF2Network: predicting transcription factor regulators and gene regulatory networks in Arabidopsis using publicly available binding site information

Kulkarni, S. R.; Vaneechoutte, D.; Van de Velde, J.; Vandepoele, K.

10.1101/173559 — bioinformatics — Posted on 2017-11-09

1181 Accurate Reconstruction of Microbial Strains from Metagenomic Sequencing Using Representative Reference Genomes

Zhou, Z.; Luhmann, N.; Alikhan, N.-F.; Quince, C.; Achtman, M.

10.1101/215707 — bioinformatics — Posted on 2017-11-09

1182 Can we meet global challenges for elimination of Hepatitis B Virus infection by 2030? Vaccine-mediated immunity in a South African cohort and a model of transmission and prevention

McNaughton, A.; Lourenco, J.; Hattingh, L.; Adland, E.; Daniels, S.; van Zyl, A.; Akiror, C. S.; Wareing, S.; Jeffery, K.; Ansari, A.; Klenerman, P.; Goulder, P.; Gupta, S.; Jooste, P.; Matthews, P. C.

10.1101/162594 — microbiology — Posted on 2017-11-09

1183 SRGAP2 And The Gradual Evolution Of The Modern Human Language Faculty

Martins, P. T.; Mari, M.; Boeckx, C.

10.1101/143248 — genetics — Posted on 2017-11-09

1184 Plant phenology supports the multi-emergence hypothesis for Ebola spillover events

Wollenberg Valero, K. C.; Isokpehi, R.; Douglas, N. E.; Sivasundaram, S.; Johnson, B.; Wootson, K.; McGill, A.

10.1101/158568 — epidemiology — Posted on 2017-11-09

1185 Towards an Integrated Map of Genetic Interactions in Cancer Cells

Rauscher, B.; Heigwer, F.; Henkel, L.; Hielscher, T.; Voloshanenko, O.; Boutros, M.

10.1101/120964 — systems biology — Posted on 2017-11-09

1186 Auditory Figure-Ground Segregation is Impaired by High Visual Load

Molloy, K.; Lavie, N.; Chait, M.

10.1101/216846 — neuroscience — Posted on 2017-11-09

1187 Cognitive Entities Underpinning Task Episodes

Farooqui, A. A.; Manly, T.

10.1101/216796 — neuroscience — Posted on 2017-11-09

1188 Limits on prediction in language comprehension: A multi-lab failure to replicate evidence for probabilistic pre-activation of phonology

Nieuwland, M.; Politzer-Ahles, S.; Heyselaar, E.; Segaert, K.; Darley, E.; Kazanina, N.; Von Grebmer Zu Wolfsthurn, S.; Bartolozzi, F.; Kogan, V.; Ito, A.; Meziere, D.; Barr, D. J.; Rousselet, G.; Ferguson, H. J.; Busch-Moreno, S.; Fu, X.; Tuomainen, J.; Kulakova, E.; Husband, E. M.; Donaldson, D. I.; Kohut, Z.; Rueschemeyer, S.-A.; Huettig, F.

10.1101/111807 — neuroscience — Posted on 2017-11-09

1189 Visual working memory is independent of the cortical spacing between memoranda

Harrison, W. J.; Bays, P. M.

10.1101/216341 — neuroscience — Posted on 2017-11-09

1190 The microbiome and resistome of hospital sewage during passage through the community sewer system

Buelow, E.; Bayjanov, J. R.; Willems, R. J. L.; Bonten, M. J. M.; Schmitt, H.; Van Schaik, W.

10.1101/216242 — microbiology — Posted on 2017-11-09

1191 Pyk2 suppresses contextual fear memory in a kinase-independent manner

Suo, L.; Zheng, J.; Zhou, Y.; Jia, L.; Kuang, Y.; Wu, Q.

10.1101/216770 — genetics — Posted on 2017-11-09

1192 Exportin Crm1 is repurposed as a docking protein to generate microtubule organizing centers at the nuclear pore

Bao, X.; Spanos, C.; Kojidani, T.; Lynch, E.; Rappsilber, J.; Hiraoka, Y.; Haraguchi, T.; Sawin, K.

10.1101/216838 — cell biology — Posted on 2017-11-09

1193 Structural centrosome aberrations promote non-cell-autonomous invasiveness

Ganier, O.; Schnerch, D.; Oertle, P.; Lim, R. Y. H.; Plodinec, M.; Nigg, E. A.

10.1101/216804 — cell biology — Posted on 2017-11-09

1194 DiscoSnp-RAD: de novo detection of small variants for population genomics

Gauthier, J.; Mouden, C.; Suchan, T.; Alvarez, N.; Arrigo, N.; Riou, C.; Lemaitre, C.; Peterlongo, P.

10.1101/216747 — bioinformatics — Posted on 2017-11-09

1195 Module analysis captures pancancer (epi)genetically deregulated cancer driver genes for smoking and antiviral response

Champion, M.; Brennan, K.; Croonenborghs, T.; Gentles, A. J.; Pochet, N.; Gevaert, O.

10.1101/216754 — bioinformatics — Posted on 2017-11-09

1196 GrapeTree: Visualization of core genomic relationships among 100,000 bacterial pathogens

Zhou, Z.; Alikhan, N.-F.; Sergeant, M. J.; Luhmann, N.; Vaz, C.; Francisco, A. P.; Carrico, J. A.; Achtman, M.

10.1101/216788 — bioinformatics — Posted on 2017-11-09

1197 Improving the calling of non-invasive prenatal testing on 13-/18-/21-trisomy by support vector machine discrimination

Yang, J.; Ding, X.; Zhu, W.

10.1101/216689 — bioinformatics — Posted on 2017-11-09

1198 Chunking sequence information by mutually predicting recurrent neural networks

Asabuki, T.; Hiratani, N.; Fukai, T.

10.1101/215392 — neuroscience — Posted on 2017-11-09

1199 The application of zeta diversity as a continuous measure of compositional change in ecology

McGeoch, M. A.; Latombe, G.; Andrew, N. R.; Nakagawa, S.; Nipperess, D. A.; Roige, M.; Marzinelli, E. M.; Campbell, A. H.; Verges, A.; Thomas, T.; Steinberg, P. D.; Selwood, K. E.; Hui, C.

10.1101/216580 — ecology — Posted on 2017-11-09

1200 Breaking the spell of nestedness

Payrato Borras, C.; Hernandez, L.; Moreno, Y.

10.1101/216564 — ecology — Posted on 2017-11-09

1201 Visual attention is not always spatially coupled to subsequent oculomotor program

Wollenberg, L.; Deubel, H.; Szinte, M.

10.1101/216572 — neuroscience — Posted on 2017-11-09

1202 Condensin’s ATPase Machinery Drives and Dampens Mitotic Chromosome Condensation

Elbatsh, A. M. O.; Raaijmakers, J. A.; van der Weide, R. H.; uit de Bos, J.; Teunissen, H.; Bravo, S.; Medema, R. H.; de Wit, E.; Haering, C. H.; Rowland, B. D.

10.1101/216630 — molecular biology — Posted on 2017-11-08

1203 Biophysical models reveal the relative importance of transporter proteins and impermeant anions in chloride homeostasis

Düsterwald, K. M.; Currin, C. B.; Burman, R. J.; Akerman, C. J.; Kay, A. R.; Raimondo, J. V.

10.1101/216150 — neuroscience — Posted on 2017-11-08

1204 Down Feather Structure Varies Between High And Low Elevation Male Andean Torrent Ducks (Merganetta armata)

Cheek, R. G.; Alza, L.; McCracken, K.

10.1101/207555 — zoology — Posted on 2017-11-08

1205 A large, open source dataset of stroke anatomical brain images and manual lesion segmentations

Liew, S.-L.; Anglin, J. M.; Banks, N. W.; Sondag, M.; Ito, K. L.; Kim, H.; Chan, J.; Ito, J.; Jung, C.; Khoshab, N.; Lefebvre, S.; Nakamura, W.; Saldana, D.; Schmiesing, A.; Tran, C.; Vo, D.; Ard, T.; Heydari, P.; Kim, B.; Aziz-Zadeh, L.; Cramer, S. C.; Liu, J.; Soekadar, S.; Nordvik, J.-E.; Westlye, L. T.; Wang, J.; Winstein, C.; Yu, C.; Ai, L.; Koo, B.; Craddock, R. C.; Miham, M.; Lakich, M.; Pienta, A.; Stroud, A.

10.1101/179614 — neuroscience — Posted on 2017-11-08

1206 Plasmodium falciparum dipeptidyl aminopeptidase 3 activity is important for efficient erythrocyte invasion by the malaria parasite

Lehmann, C.; Tan, M. S. Y.; de Vries, L. E.; Russo, I.; Sanchez, M. I.; Goldberg, D. E.; Deu, E.

10.1101/202812 — microbiology — Posted on 2017-11-08

1207 Butterflyfishes as a System for Investigating Pair Bonding

Nowicki, J.; O'Connell, L.; Cowman, P. F.; Walker, S.; Coker, D.; Pratchett, M.

10.1101/214544 — ecology — Posted on 2017-11-08

1208 Visual working memory is independent of the cortical spacing between memoranda

Harrison, W. J.; Bays, P. M.

10.1101/216341 — neuroscience — Posted on 2017-11-08

1209 Deconstructing Procedural Memory: Different Learning Trajectories and Consolidation of Sequence and Statistical Learning

Simor, P.; Zavecz, Z.; Horvath, K.; Elteto, N.; Torok, C.; Pesthy, O.; Janacsek, K.; Nemeth, D.

10.1101/216374 — neuroscience — Posted on 2017-11-08

1210 Biophysics of object segmentation in a collision-detecting neuron

Dewell, R. B.; Gabbiani, F.

10.1101/216333 — neuroscience — Posted on 2017-11-08

1211 Coupling MALDI-TOF mass spectrometry protein and specialized metabolite analyses to rapidly discriminate bacterial function

Clark, C. M.; Costa, M. S.; Sanchez, L. M.; Murphy, B. T.

10.1101/215350 — microbiology — Posted on 2017-11-08

1212 Could cyanobacteria have made the salinity transition during the late Archean?

Gehringer, M. M.; Achim, H.

10.1101/216416 — microbiology — Posted on 2017-11-08

1213 Influence of Oenococcus oeni and Brettanomyces bruxellensis on Aged Wine Microbial Taxonomic and Functional Profiles

Zepeda Mendoza, M. L.; Edwards, N. K.; Madsen, M. G.; Abel-Kistrup, M.; Puetz, L.; Sicheritz-Ponten, T.; Swiegers, J. H.

10.1101/216390 — microbiology — Posted on 2017-11-08

1214 Russian Doll Genes and Complex Chromosome Rearrangements in Oxytricha trifallax

Braun, J.; Nabergall, L.; Neme, R.; Landweber, L. F.; Saito, M.; Jonoska, N.

10.1101/216440 — genomics — Posted on 2017-11-08

1215 Gene expression in cord blood links genetic risk for neurodevelopmental disorders with maternal psychological distress and adverse childhood outcomes

Breen, M. S.; Wingo, A. P.; Koen, N.; Donald, K. A.; Zar, H. J.; Ressler, K. J.; Buxbaum, J. D.; Stein, D. J.

10.1101/216309 — developmental biology — Posted on 2017-11-08

1216 Soluble Syntaxin 3 Functions as a Transcription Regulator

Giovannone, A. J.; Winterstein, C.; Bhattaram, P.; Reales, E.; Low, S. H.; Baggs, J. E.; Xu, M.; Lalli, M. A.; Hogenesch, J. B.; Weimbs, T.

10.1101/162958 — cell biology — Posted on 2017-11-08

1217 PAIRUP-MS: Pathway Analysis and Imputation to Relate Unknowns in Profiles from Mass Spectrometry-based metabolite data

Hsu, Y.-H. H.; Churchhouse, C.; Pers, T. H.; Mercader, J. M.; Metspalu, A.; Fischer, K.; Fortney, K.; Morgen, E. K.; Gonzalez, C.; Gonzalez, M. E.; Esko, T.; Hirschhorn, J. N.

10.1101/209577 — bioinformatics — Posted on 2017-11-08

1218 Identifying Crohns disease signal from variome analysis

Wang, Y.; Astrakhan, Y.; Petersen, B.-S.; Schreiber, S.; Franke, A.; Bromberg, Y.

10.1101/216432 — bioinformatics — Posted on 2017-11-08

1219 De novo Clustering of Gene Expressed Variants in Transcriptomic Long Reads Data Sets

Marchet, C.; Lecompte, L.; Da Silva, C.; Cruaud, C.; Aury, J. M.; Nicolas, J.; Peterlongo, P.

10.1101/170035 — bioinformatics — Posted on 2017-11-08

1220 Knockdown of Liver-Derived C1 Inhibitor Results in Brain Pathology in mice

Farfara, D.; Feierman, E.; Richards, A.; Revenko, A. S.; MacLeod, R. A.; Norris, E. H.; Strickland, S.

10.1101/216531 — neuroscience — Posted on 2017-11-08

1221 Bayesian Reconstruction of Transmission within Outbreaks using Genomic Variants

De Maio, N.; Worby, C. J.; Wilson, D. J.; Stoesser, N.

10.1101/213819 — genetics — Posted on 2017-11-08

1222 AptaBlocks: Accelerating the Design of RNA-based Drug Delivery Systems

Wang, Y.; Hoinka, J.; Swiderski, P.; Przytycka, T.

10.1101/216465 — bioinformatics — Posted on 2017-11-08

1223 Aligning sequences to general graphs in O(V + mE) time

Rautiainen, M.; Marschall, T.

10.1101/216127 — bioinformatics — Posted on 2017-11-08

1224 Transcriptional profiling reveals extraordinary diversity among skeletal muscle tissues

Terry, E. E.; Zhang, X.; Hoffmann, C.; Hughes, L. D.; Lewis, S. A.; Li, J.; Riley, L.; Lahens, N. F.; Gong, M.; Andrade, F.; Esser, K. A.; Hughes, M. E.

10.1101/216317 — systems biology — Posted on 2017-11-08

1225 The genome sequence of the wild tomato Solanum pimpinellifolium provides insights into salinity tolerance

Razali, R.; Bougouffa, S.; Morton, M. J. L.; Lightfoot, D. J.; Alam, I.; Essack, M.; Arold, S. T.; Kamau, A.; Schmöckel, S. M.; Pailles, Y.; Shahid, M.; Michell, C. T.; Al-Babili, S.; Ho, Y. S.; Tester, M.; Bajic, V. B.; Negrao, S.

10.1101/215517 — plant biology — Posted on 2017-11-08

1226 Russian Doll Genes and Complex Chromosome Rearrangements in Oytricha trifallax

Braun, J.; Nabergall, L.; Neme, R.; Landweber, L.; Saito, M.; Jonoska, N.

10.1101/216440 — genomics — Posted on 2017-11-08

1227 Mouse lemurs and degraded habitat

Knoop, S.; Chikhi, L.; Salmona, J.

10.1101/216382 — ecology — Posted on 2017-11-08

1228 Harnessing Human Connectome Project Data for Replication Studies: A Demonstration for Resting State-Task Network Correspondence

Nickerson, L. D.

10.1101/111021 — neuroscience — Posted on 2017-11-08

1229 Detecting polygenic adaptation in admixture graphs

Racimo, F.; Berg, J. J.; Pickrell, J. K.

10.1101/146043 — evolutionary biology — Posted on 2017-11-08

1230 Soluble Syntaxin 3 Functions as a Transcription Regulator

Giovannone, A. J.; Winterstein, C.; Bhattaram, P.; Reales, E.; Low, S. H.; Baggs, J. E.; Xu, M.; Lalli, M. A.; Hogenesch, J. B.; Weimbs, T.

10.1101/162958 — cell biology — Posted on 2017-11-08

1231 Transcriptional Changes of DNA Replication and Repair Factors Over Uveal Melanoma Subtypes

Kucherlapati, M. H.

10.1101/214932 — cancer biology — Posted on 2017-11-08

1232 Accurate, Sensitive, and Precise Multiplexed Proteomics using the Complement Reporter Ion Cluster

Sonnett, M.; Yeung, E.; Wuhr, M.

10.1101/205054 — systems biology — Posted on 2017-11-08

1233 Genome-Wide Association Study of Ionomics Traits on Diverse Soybean Populations from Germplasm Collections

Ziegler, G.; Nelson, R.; Granada, S.; Krishnan, H. B.; Gillman, J. D.; Baxter, I.

10.1101/079731 — genetics — Posted on 2017-11-08

1234 An analytical framework to understand regulatory novelty accompanying allopolyploidization

Hu, G.; Wendel, J. F.

10.1101/212092 — evolutionary biology — Posted on 2017-11-08

1235 Enumerating the Economic Cost of Antimicrobial Resistance Per Antibiotic Consumed to Inform the Evaluation of Interventions Affecting their Use

Shrestha, P.; Cooper, B. S.; Coast, J.; Oppong, R.; Do, N. T. T.; Podha, T.; Guerin, P. J.; Wertheim, H. F.; Lubell, Y.

10.1101/206656 — epidemiology — Posted on 2017-11-08

1236 Lack of insurance is associated with lower probability of diagnostic imaging use among US trauma patients: An instrumental variable analysis and simulation

Renson, A.; Schubert, F. D.; Bjurlin, M. A.

10.1101/215889 — epidemiology — Posted on 2017-11-08

1237 A Pilot Randomized Trial of Oral Magnesium Supplementation on Supraventricular Arrhythmias

Lutsey, P. L.; Chen, L. Y.; Eaton, A.; Jaeb, M.; Rudser, K. D.; Neaton, J. D.; Alonso, A.

10.1101/215319 — clinical trials — Posted on 2017-11-08

1238 SpatialDE - Identification of spatially variable genes

Svensson, V.; Teichmann, S. A.; Stegle, O.

10.1101/143321 — genomics — Posted on 2017-11-08

1239 Planetary-wide organization of human navigation ability

Coutrot, A.; Silva, R.; Manley, E.; de Cothi, W.; Sami, S.; Bohbot, V.; Wiener, J.; Hölscher, C.; Dalton, R. C.; Hornberger, M.; Spiers, H.

10.1101/188870 — neuroscience — Posted on 2017-11-08

1240 The Genetic Intractability Of Symbiodinium microadriaticum To Standard Algal Transformation Methods

Chen, J. E.; Barbrook, A. C.; Cui, G.; Howe, C. J.; Aranda Lastra, M.

10.1101/140616 — molecular biology — Posted on 2017-11-08

1241 Towards sustainable bioplastic production in resource limited environments using the photoferroautotrophic and photoelectroautotrophic bacterium Rhodopseudomonas palustris TIE-1

Ranaivoarisoa, T. O.; Rengasamy, K.; Guzman, M. S.; Singh, R.; Bose, A.

10.1101/214551 — microbiology — Posted on 2017-11-08

1242 Minimum requirements for reprogramming and maintaining cell fate in the Arabidopsis root

Drapek, C.; Sparks, E. E.; Marhavy, P.; Andersen, T. G.; Hennacy, J. H.; Geldner, N.; Benfey, P. N.

10.1101/214957 — developmental biology — Posted on 2017-11-08

1243 HapCHAT: Adaptive haplotype assembly for efficiently leveraging high coverage in long reads

Beretta, S.; Patterson, M.; Marschall, T.; Martin, M.; Zaccaria, S.; Della Vedova, G.; Bonizzoni, P.

10.1101/170225 — bioinformatics — Posted on 2017-11-08

1244 A biophysical dynamic module for the polarisation of auxin efflux carriers PIN-FORMED (PIN)

Hernandez-Hernandez, V.; Barrio, R. A.; Benitez, M.; Nakayama, N.; Romero-Arias, J. R.; Villarreal, C.

10.1101/216275 — plant biology — Posted on 2017-11-08

1245 Transcriptomic and morphophysiological evidence for a specialized human cortical GABAergic cell type

Boldog, E.; Bakken, T.; Hodge, R. D.; Novotny, M.; Aevermann, B. D.; Baka, J.; Borde, S.; Close, J. L.; Diez-Fuertes, F.; Ding, S.-L.; Farago, N.; Kocsis, A. K.; Kovacs, B.; McCorrison, J. M.; Miller, J. A.; Molnar, G.; Olah, G.; Ozsvar, A.; Rozsa, M.; Shehata, S.; Smith, K. A.; Sunkin, S. M.; Tran, D. N.; Venepally, P.; Wall, A.; Puskas, L. G.; Barzo, P.; Steemers, F. J.; Schork, N. J.; Scheuermann, R. H.; Lasken, R. S.; Lein, E. S.; Tamas, G.

10.1101/216085 — neuroscience — Posted on 2017-11-08

1246 Transcriptional Profiling of Somatostatin Interneurons in the Spinal Dorsal Horn

Chamessian, A.; Young, M.; Qadri, Y.; Berta, T.; Ji, R.-R.; Van de Ven, T.

10.1101/215657 — neuroscience — Posted on 2017-11-08

1247 Reactivating vocabularies in the elderly

Cordi, M.; Schreiner, T.; Rasch, B.

10.1101/216283 — neuroscience — Posted on 2017-11-08

1248 Local network-level integration mediates effects of transcranial Alternating Current Stimulation

Fusca, M.; Ruhnau, P.; Neuling, T.; Weisz, N.

10.1101/216176 — neuroscience — Posted on 2017-11-08

1249 Preparation for mental effort recruits Dorsolateral Prefrontal Cortex: an fNIRS investigation

Vassena, E.; Gerrits, R.; Demanet, J.; Verguts, T.; Siugzdaite, R.

10.1101/216036 — neuroscience — Posted on 2017-11-08

1250 Basal forebrain control of olfactory bulb interneurons

Sanz Diez, A.; Najac, M.; De Saint Jan, D.

10.1101/216259 — neuroscience — Posted on 2017-11-08

1251 Revealing structure components of the retina by deep learning networks

Yan, Q.; Yu, Z.; Chen, F.; Liu, J. K.

10.1101/216010 — neuroscience — Posted on 2017-11-08

1252 Mitochondrial Ultrastructure Is Coupled to Synaptic Performance at Axonal Release Sites

Cserep, C.; Posfai, B.; Schwarcz, A. D.; Denes, A.

10.1101/216093 — neuroscience — Posted on 2017-11-08

1253 Divergent effects of healthy ageing on semantic knowledge and control: Evidence from novel comparisons with semantically-impaired patients

Hoffman, P.

10.1101/216192 — neuroscience — Posted on 2017-11-08

1254 Multiplexed temporally focused light shaping for high-resolutionmulti-cell targeting

Accanto, N.; Tanese, D.; Ronzitti, E.; Molinier, C.; Newman, Z. L.; Wyart, C.; Isacoff, E.; Papagiakoumou, E.; Emiliani, V.

10.1101/216135 — neuroscience — Posted on 2017-11-08

1255 Streptococcus pyogenes infection and the human proteome with a special focus on the IgG-cleaving enzyme IdeS

Karlsson, C. A. Q.; Järnum, S.; Winstedt, L.; Kjellman, C.; Björck, L.; Linder, A.; Malmström, J. A.

10.1101/214890 — microbiology — Posted on 2017-11-08

1256 Immune signatures correlate with L1 retrotransposition in gastrointestinal cancers

Jung, H.; Choi, J. K.; Lee, E. A.

10.1101/216051 — genomics — Posted on 2017-11-08

1257 Environmental DNA: a new low-cost monitoring tool for pathogens in salmonid aquaculture.

Peters, L.; Spatharis, S.; Dario, M. A.; Roca, I. J. T.; Kintner, A.; Kanstad-Hanssen, O.; Llewellyn, M. S.; Praebel, K.

10.1101/215483 — genetics — Posted on 2017-11-08

1258 Genome scan identifies flowering-independent effects of barley HsDry2.2 locus on yield traits under water deficit

Merchuk-Ovnat, L.; Silberman, R.; Laiba, E.; Maurer, A.; Pillen, K.; Faigenboim, A.; Fridman, E.

10.1101/216002 — genetics — Posted on 2017-11-08

1259 Genetic structure of a patchily-distributed philopatric migrant: implications for management and conservation

Bounas, A.; Tsaparis, D.; Efrat, R.; Gradev, G.; Gustin, M.; Mikulic, K.; Rodriguez, A.; Sara, M.; Kotoulas, G.; Sotiropoulos, K.

10.1101/216069 — genetics — Posted on 2017-11-08

1260 Do priority effects outweigh environmental filtering in a guild of dominant freshwater macroinvertebrates?

Little, C. J.; Altermatt, F.

10.1101/216267 — ecology — Posted on 2017-11-08

1261 Bulk degradation of dendritic cargos requires Rab7-dependent transport in Rab7-positive/LAMP1-negative endosomes to somatic lysosomes.

Yap, C. C.; Digilio, L.; McMahon, L.; Garcia, D. A.; Winckler, B.

10.1101/215970 — cell biology — Posted on 2017-11-08

1262 Swr1 mediated H2A.Z/Pht1 incorporation designates centromere DNA for de novo CENP-A/Cnp1 assembly

Kulasegaran-Shylini, R.; Subramanian, L.; Kerr, A. R.; Spanos, C.; Rappsilber, J.; Allshire, R. C.

10.1101/215962 — cell biology — Posted on 2017-11-08

1263 Formation and disassembly of a contractile actomyosin network mediates content release from large secretory vesicles

Segal, D.; Zaritsky, A.; Schejter, E. D.; Shilo, B. Z.

10.1101/216044 — cell biology — Posted on 2017-11-08

1264 Targeting stromal remodeling and cancer stem cell plasticity to overcome chemoresistance in triple negative breast cancer

Cazet, A. S.; Hui, M. N.; Elsworth, B. L.; Wu, S. Z.; Roden, D.; Chan, C.-L.; Skhinas, J. N.; Collot, R.; Yang, J.; Harvey, K.; Johan, M. Z.; Cooper, C.; Nair, R.; Herrmann, D.; McFarland, A.; Deng, N.-T.; Ruiz-Borrego, M.; Rojo, F.; Trigo, J. M.; Bezares, S.; Caballero, R.; Lim, E.; Timpson, P.; O'Toole, S.; Watkins, D. N.; Cox, T. R.; Samuel, M.; Martin, M.; Swarbrick, A.

10.1101/215954 — cancer biology — Posted on 2017-11-08

1265 Deimination of arginine at the C-terminal domain favors RNA polymerase II pause release

Sharma, P.; Lioutas, A.; Quilez, J.; Wright, R. H. G.; Di Vona, C.; Le Dily, F.; Schuller, R.; Eick, D.; Beato, M.

10.1101/216143 — cancer biology — Posted on 2017-11-08

1266 Continuous high-resolution in vivo imaging reveals tumor-specific dissemination in an embryonic zebrafish xenograft model

Asokan, N.; Daetwyler, S.; Bernas, S. N.; Schmied, C.; Volger, S.; Lambert, K.; Wobus, M.; Wermke, M.; Kempermann, G.; Huisken, J.; Brand, M.; Bornhaeuser, M.

10.1101/215921 — cancer biology — Posted on 2017-11-08

1267 Recurrent loss of heterozygosity correlates with clinical outcome in pancreatic neuroendocrine cancer

Lawrence, B.; Blenkiron, C.; Parker, K.; Tsai, P.; Fitzgerald, S.; Shields, P.; Yeong, M. L.; Kramer, N.; Robb, T.; James, S. M.; Black, M.; Fan, V.; Poonawala, N.; Yap, P.; Coats, E.; Woodhouse, B.; Ramsaroop, R.; Yozu, M.; Robinson, B.; Henare, K.; Koea, J.; Johnston, P.; Carroll, R.; Connor, S.; Morrin, H.; Elston, M.; Jackson, C.; Reid, P.; Windsor, J.; MacCormick, A.; Babor, R.; Bartlett, A.; Damianovich, D.; Knowlton, N.; Grimmond, S.; Findlay, M.; Print, C. G.

10.1101/214585 — cancer biology — Posted on 2017-11-08

1268 Ennet: exert enhaner-only somatic mutations to discover potential cancer-driving biological networks

Cui, Y.; Niu, Y.; Teng, X.; Wang, D.; Luo, H.; Zhang, P.; Wu, W.; He, S.; Luo, J.; Chen, R.

10.1101/216226 — bioinformatics — Posted on 2017-11-08

1269 Panaconda: Application of pan-synteny graph models to genome content analysis

Warren, A. S.; Davis, J. J.; Wattam, A. R.; Machi, D.; Setubal, J. C.; Heath, L.

10.1101/215988 — bioinformatics — Posted on 2017-11-08

1270 TraRECo: A Greedy Approach based de novo Transcriptome Assembler with Read Error Correction using Consensus Matrix

Yoon, S.; Kim, D.; Kang, K.; Park, W. J.

10.1101/216077 — bioinformatics — Posted on 2017-11-08

1271 PRS-on-Spark: a novel, efficient and flexible approach for generating polygenic risk scores

Chen, L. M.; Yao, N.; Garg, E.; Zhu, Y.; Nguyen, T. T. T.; Pokhvisneva, I.; Hari Dass, S. A.; Forest, M.; Greenwood, C.; Silveira, P. P.; Meaney, M. J.; O'Donell, K. J.

10.1101/209833 — bioinformatics — Posted on 2017-11-08

1272 Guanosine monophosphate reductase 1 is a potential therapeutic target for Alzheimer’s disease

Liu, H.; Luo, K.

10.1101/215947 — bioinformatics — Posted on 2017-11-08

1273 Male parental investment reflects the level of partner contributions and brood value in tree swallows

Lendvai, A. Z.; Akcay, C.; Stanback, M.; Haussmann, M. F.; Moore, I. T.; Bonier, F.

10.1101/216119 — animal behavior and cognition — Posted on 2017-11-08

1274 Piper longum: A review of its phytochemicals and their network pharmacological evaluation

Choudhary, N.; Singh, V.

10.1101/169763 — systems biology — Posted on 2017-11-08

1275 Neural Networks for Efficient Bayesian Decoding of Natural Images from Retinal Neurons

Parthasarathy, N.; Batty, E.; Falcon, W.; Rutten, T.; Rajpal, M.; Chichilnisky, E. J.; Paninski, L.

10.1101/153759 — neuroscience — Posted on 2017-11-08

1276 Antidiabetic “gliptins” affect biofilm formation by Streptococcus mutans

De, A.; Pompilio, A.; Francis, J.; Sutcliffe, I. C.; Black, G. W.; Lupidi, G.; Petrelli, D.; Vitali, L. A.

10.1101/157503 — microbiology — Posted on 2017-11-08

1277 RSV Downregulates IL-21/IL-21R On TFH Cells Via PD-L1 Induction In APCs Impairing Protective Humoral Responses

Benedetti Gassen, R.; Fazolo, T.; Nascimento de Freitas, D.; Borges, T. J.; Maito, F.; Mendes, D. A. G. B.; Bafica, A.; Rodrigues, L. C.; Duarte de Souza, A. P.; Bonorino, C.

10.1101/203133 — immunology — Posted on 2017-11-08

1278 Finite-sample genome-wide regression p-values (GWRPV) with a non-normally distributed phenotype

Connor, G.; O'Neill, M.

10.1101/204727 — genomics — Posted on 2017-11-08

1279 Reconstruction of body mass evolution in the Cetartiodactyla and mammals using phylogenomic data

Figuet, E.; Ballenghien, M.; Lartillot, N.; Galtier, N.

10.1101/139147 — evolutionary biology — Posted on 2017-11-08

1280 Endothelial Cell-Specific MCPIP Deletion Causes Endothelial Dysfunction and Impairs Post-ischemic Angiogenesis in Vivo

Niu, J.; Kapoor, N.; Liang, J.; Jin, Z.; Becerra, E.; Kolattukudy, P. E.

10.1101/208884 — pathology — Posted on 2017-11-07

1281 A common framework for the problem of derivingestimates of dynamic functional brain connectivity.

Thompson, W. H.; Fransson, P.

10.1101/215772 — neuroscience — Posted on 2017-11-07

1282 Prefrontal cortex regulates amygdala response to threat in trait anxiety

Ironside, M.; Browning, M.; Ansari, T.; Harvey, C.; Sekyi-Djan, M.; Bishop, S.; Harmer, C.; O'Shea, J.

10.1101/215699 — neuroscience — Posted on 2017-11-07

1283 Addressing the reliability fallacy: Similar group effects may arise from unreliable individual effects

Fröhner, J. H.; Teckentrup, V.; Smolka, M. N.; Kroemer, N. B.

10.1101/215053 — neuroscience — Posted on 2017-11-07

1284 Multifactorial Dynamics of White Matter Connectivity During Adolescence

Tunc, B.; Parker, D.; Shinohara, R. T.; Elliott, M. A.; Ruparel, K.; Gur, R. E.; Gur, R. C.; Verma, R.

10.1101/215152 — neuroscience — Posted on 2017-11-07

1285 The Drosophila small conductance potassium channel (SK) negatively regulates nociception.

Walcott, K.; Mauthner, S.; Tsubouchi, A.; Robertson, J.; Tracey, D.

10.1101/208868 — neuroscience — Posted on 2017-11-07

1286 Acute memory deficits in chemotherapy-treated adults

Lindner, O. C.; Mayes, A.; McCabe, M. G.; Talmi, D.

10.1101/215731 — neuroscience — Posted on 2017-11-07

1287 The medial temporal lobe organizes memory across time and space: Causal evidence from brain stimulation

Goyal, A.; Miller, J.; Watrous, A. J.; Lee, S. A.; Coffey, T.; Sperling, M.; Sharan, A.; Worrell, G.; Brent, B.; Lega, B.; Jobst, B. C.; Davis, K.; Gross, R.; Sheth, S.; Ezzyat, Y.; Das, S.; Stein, J.; Gorniak, R.; Kahana, M.; Rizzuto, D.; Jacobs, J.

10.1101/215806 — neuroscience — Posted on 2017-11-07

1288 Identification of stable reference genes for quantitative PCR in koalas

Sarker, N.; Fabijan, J.; Emes, R. D.; Hemmatzadeh, F.; Meers, J.; Moreton, J.; Owen, H.; Seddon, J. M.; Simmons, G.; Speight, N.; Trott, D.; Woolford, L.; Tarlinton, R.

10.1101/215681 — molecular biology — Posted on 2017-11-07

1289 Needle in a haystack? A comparison of eDNA metabarcoding and targeted qPCR for detection of great crested newt (Triturus cristatus)

Harper, L. R.; Lawson Handley, L.; Hahn, C.; Boonham, N.; Rees, H. C.; Gough, K. C.; Lewis, E.; Adams, I. P.; Brotherton, P.; Phillips, S.; Haenfling, B.

10.1101/215897 — molecular biology — Posted on 2017-11-07

1290 Mannan molecular sub-structures control nanoscale glucan exposure in Candida

Graus, M. S.; Wester, M. J.; Lowman, D. W.; Williams, D. L.; Kruppa, M. D.; Young, J. M.; Pappas, H. C.; Lidke, K. A.; Neumann, A.

10.1101/215632 — microbiology — Posted on 2017-11-07

1291 Metagenomics for chronic meningitis: clarifying interpretation and diagnosis

Wilson, M. R.; O'Donovan, B. D.; Gelfand, J. M.; Sample, H. A.; Chow, F. C.; Betjemann, J. P.; Shah, M. P.; Richie, M. B.; Gorman, M. P.; Hajj-Ali, R. A.; Calabrese, L. H.; Zorn, K. C.; Greenlee, J. E.; Blum, J. H.; Green, G.; Khan, L. M.; Banerji, D.; Langelier, C.; Bryson-Cahn, C.; Harrington, W.; Lingappa, J. R.; Shanbhag, N. M.; Green, A. J.; Brew, B. J.; Soldatos, A.; Strnad, L.; Doernberg, S. B.; Jay, C. A.; Douglas, V.; Josephson, S. A.; DeRisi, J. L.

10.1101/213561 — microbiology — Posted on 2017-11-07

1292 Genome-wide association study of habitual physical activity in over 277,000 UK Biobank participants identifies multiple variants including CADM2 and APOE

Klimentidis, Y. C.; Raichlen, D. A.; Bea, J.; Garcia, D. O.; Mandarino, L. J.; Alexander, G. E.; Chen, Z.; Going, S. B.

10.1101/179317 — genetics — Posted on 2017-11-07

1293 Building a schizophrenia genetic network: Evidence that Transcription Factor 4 regulates schizophrenia risk genes.

Xia, H.; Jahr, F. M.; Kim, N.-K.; Xie, L.; Shabalin, A. A.; Bryois, J.; Sweet, D. H.; Kronfol, M. M.; Palasuberniam, P.; McRae, M.; Riley, B. P.; Sullivan, P. F.; van den Oord, E. J.; McClay, J.

10.1101/215715 — genetics — Posted on 2017-11-07

1294 Predicting Global Forest Reforestation Potential

Crowther, T. W.; Glick, H. B.; Maynard, D. S.; Ashley-Cantello, W.; Evans, T.; Routh, D.

10.1101/210062 — ecology — Posted on 2017-11-07

1295 Postural sway during single-legged standing is dependent on the body position assumption strategy and supports the stability and mobility trade-off hypothesis

Bacik, B.; Sobota, G.; Fredyk, A.; Słomka, K. J.; Juras, G.

10.1101/215905 — animal behavior and cognition — Posted on 2017-11-07

1296 Developmental cognitive neuroscience using Latent Change Score models: A tutorial and applications

Kievit, R.; Brandmaier, A.; Ziegler, G.; van Harmelen, A.-L.; de Mooij, S.; Moutoussis, M.; Goodyer, I.; Bullmore, E.; Jones, P.; Fonagy, P.; NSPN Consortium, ; Lindenberger, U.; Dolan, R.

10.1101/110429 — neuroscience — Posted on 2017-11-07

1297 N-terminal sumoylation of centromeric histone H3 variant Cse4 regulates its proteolysis to prevent mislocalization to non-centromeric chromatin

Ohkuni, K.; Levy-Myers, R.; Warren, J.; Au, W.-C.; Takahashi, Y.; Baker, R. E.; Basrai, M. A.

10.1101/176206 — molecular biology — Posted on 2017-11-07

1298 Identifying the phenotypic effect of rare variants by including between-pedigree coancestry in variance components linkage analysis

Hicks, J. E.; Province, M. A.

10.1101/215863 — genetics — Posted on 2017-11-07

1299 Control of Genetic Parasites Mediated Through Nucleoporin Evolution

Rowley, P. A.; Patterson, K.; Sandmeyer, S. B.; Sawyer, S. L.

10.1101/215913 — evolutionary biology — Posted on 2017-11-07

1300 Motor-Like Properties of Non-Motor Enzymes

Slochower, D. R.; Gilson, M. K.

10.1101/121848 — biophysics — Posted on 2017-11-07

1301 A practical tool for Maximal Information Coefficient analysis

Albanese, D.; Riccadonna, S.; Donati, C.; Franceschi, P.

10.1101/215855 — bioinformatics — Posted on 2017-11-07

1302 Modeling Spatial Genomic Interactions with the Hawkes model

Bonnet, A.; Rivoirard, V.; Picard, F.

10.1101/214874 — bioinformatics — Posted on 2017-11-07

1303 Biomarker identification for statin sensitivity of cancer cell lines

Raghu, V.; Beckwitt, C.; Warita, K.; Wells, A.; Benos, P.; Oltvai, Z.

10.1101/215756 — bioinformatics — Posted on 2017-11-07

1304 SAFE-clustering: Single-cell Aggregated (From Ensemble) Clustering for Single-cell RNA-seq Data

Yang, Y.; Huh, R.; Culpepper, H. W.; Love, M. I.; Li, Y.

10.1101/215723 — bioinformatics — Posted on 2017-11-07

1305 The locus coeruleus is a complex and differentiated neuromodulatory system

Totah, N. K.; Neves, R. M.; Panzeri, S.; Logothetis, N. K.; Eschenko, O.

10.1101/109710 — neuroscience — Posted on 2017-11-07

1306 Dose-dependent spatiotemporal responses of mammalian cells to an alkylating agent

Rancourt, A.; Sato, S.; Satoh, M. S.

10.1101/215764 — cell biology — Posted on 2017-11-07

1307 Therapeutically advantageous secondary targets of abemaciclib identified by multi-omics profiling of CDK4/6 inhibitors

Hafner, M.; Mills, C. E.; Subramanian, K.; Chen, C.; Chung, M.; Boswell, S. A.; Everley, R. A.; Walmsley, C. S.; Juric, D.; Sorger, P.

10.1101/211680 — cancer biology — Posted on 2017-11-07

1308 PKD2 is an essential ion channel subunit in the primary cilium of the renal collecting duct epithelium

Liu, X.; Vien, T.; Duan, J.; Sheu, S.-H.; DeCaen, P. G.; Clapham, D. E.

10.1101/215814 — biophysics — Posted on 2017-11-07

1309 White LED Lighting for Plants

Sharakshane, A.

10.1101/215095 — plant biology — Posted on 2017-11-07

1310 An analytical framework to understand regulatory novelty accompanying allopolyploidization

Hu, G.; Wendel, J.

10.1101/212092 — evolutionary biology — Posted on 2017-11-07

1311 Widespread ancient whole genome duplications in Malpighiales coincide with Eocene global climatic upheaval

Cai, L.; Xi, Z.; Amorim, A. M.; Sugumaran, M.; Rest, J. S.; Liu, L.; Davis, C. C.

10.1101/215608 — evolutionary biology — Posted on 2017-11-07

1312 Limited evidence for proactive and reactive spatial responses of prey to an active predator

Cusack, J.; Kohl, M. T.; Metz, M. C.; Coulson, T.; Stahler, D. R.; Smith, D. W.; MacNulty, D. R.

10.1101/215475 — ecology — Posted on 2017-11-07

1313 Centromeric DNA destabilizes H3 nucleosomes to promote CENP-A deposition during the cell cycle

Shukla, M.; Tong, P.; White, S. A.; Singh, P. P.; Reid, A. M.; Catania, S.; Pidoux, A. L.; Allshire, R. C.

10.1101/215624 — cell biology — Posted on 2017-11-07

1314 Accurate Reconstruction of Microbial Strains Using Representative Reference Genomes

Zhou, Z.; Luhmann, N.; Alikhan, N.-F.; Quince, C.; Achtman, M.

10.1101/215707 — bioinformatics — Posted on 2017-11-07

1315 Demographic variability and heterogeneity among individuals within and among clonal bacteria strains

Jouvet, L.; Rodriguez-Rojas, A.; Steiner, U. K.

10.1101/105353 — evolutionary biology — Posted on 2017-11-07

1316 MaxTiC: Fast Ranking Of A Phylogenetic Tree By Maximum Time Consistency With Lateral Gene Transfers

Chauve, C.; Rafiey, A.; Davin, A. A.; Scornavacca, C.; Veber, P.; Boussau, B.; Szollosi, G.; Daubin, V.; Tannier, E.

10.1101/127548 — evolutionary biology — Posted on 2017-11-07

1317 Predicting personality traits from resting-state fMRI

Dubois, J.; Galdi, P.; Han, Y.; Paul, L. K.; Adolphs, R.

10.1101/215129 — neuroscience — Posted on 2017-11-07

1318 "A mosquito bites and a butterfly flies": a specific response type of frontal patients in a similarity task

Garcin, B.; Volle, E.; Funkiewiez, A.; Miller, B.; Dubois, B.; Levy, R.

10.1101/215020 — neuroscience — Posted on 2017-11-07

1319 Frontal eye field inactivation reduces saccade preparation in the superior colliculus, but does not alter how preparatory activity relates to saccade latency

Dash, S.; Peel, T. R.; Lomber, S. G.; Corneil, B. D.

10.1101/215137 — neuroscience — Posted on 2017-11-07

1320 Calcimycocavitological Studies on Seashells from Beaches of North Goa, India

Dabolkar, S.; Kamat, N.

10.1101/215228 — microbiology — Posted on 2017-11-07

1321 Improving microbial electrosynthesis of polyhydroxybutyrate (PHB) from CO2 by Rhodopseudomonas palustris TIE-1 using an immobilized iron complex modified cathode

Rengasamy, K.; Ranaivoarisoa, T. O.; Singh, R.; Bose, A.

10.1101/214577 — microbiology — Posted on 2017-11-07

1322 Spin coated chitin films for biosensors and its analysis are depended on chitin-surface interactions

Casteleijn, M. G.; Richardson, D.; Parkkila, P. K.; Granqvist, N.; Urtti, A.; Viitala, T.

10.1101/215566 — biophysics — Posted on 2017-11-07

1323 Bioinformatics Workflow Management With The Wobidisco Ecosystem

Mondet, S.; Aksoy, B. A.; Rozenberg, L.; Hodes, I.; Hammerbacher, J.

10.1101/213884 — bioinformatics — Posted on 2017-11-07

1324 Resolving outbreak dynamics using Approximate Bayesian Computation for stochastic birth-death models

Lintusaari, J.; Blomstedt, P.; Sivula, T.; Gutmann, M. U.; Kaski, S.; Corander, J.

10.1101/215533 — bioinformatics — Posted on 2017-11-07

1325 DHX36 binding at G-rich sites in mRNA untranslated regions promotes translation

Sauer, M.; Juranek, S. A.; Kazemier, H. G.; Benhalevy, D.; Wang, X.; Hafner, M.; Paeschke, K.

10.1101/215541 — bioinformatics — Posted on 2017-11-07

1326 The evolutionary history of the current global Ramularia collo-cygni epidemic

Stam, R.; Sghyer, H.; Münsterkötter, M.; Pophaly, S.; Tellier, A.; Güldener, U.; Hückelhoven, R.; Hess, M.

10.1101/215418 — plant biology — Posted on 2017-11-07

1327 A bacterial GW-effector targets Arabidopsis AGO1 to promote pathogenicity and induces Effector-triggered immunity by disrupting AGO1 homeostasis

Thiebeauld, O.; Charvin, M.; Singla Rastogi, M.; Yang, F.; Pontier, D.; Pouzet, C.; Bapaume, L.; Li, G.; Deslandes, L.; Lagrange, T.; Alfano, J. R.; Navarro, L.

10.1101/215590 — plant biology — Posted on 2017-11-07

1328 Non-linear Auto-Regressive Models for Cross-Frequency Coupling in Neural Time Series

Dupre la Tour, T.; Tallot, L.; Grabot, L.; Doyere, V.; van Wassenhove, V.; Grenier, Y.; Gramfort, A.

10.1101/159731 — neuroscience — Posted on 2017-11-07

1329 Regulation of Eag by calcium/calmodulin controls presynaptic excitability in Drosophila

Bronk, P.; Kuklin, E. A.; Liu, C.; Wiggin, T. D.; Gorur-Shandilya, S.; Marder, E.; Griffith, L. C.

10.1101/215293 — neuroscience — Posted on 2017-11-07

1330 The Long and the Short of Serotonergic Stimulation: Optogenetic activation of dorsal raphe serotonergic neurons changes the learning rate for rewards

Iigaya, K.; Fonseca, M. S.; Murakami, M.; Mainen, Z. F.; Dayan, P.

10.1101/215400 — neuroscience — Posted on 2017-11-07

1331 Chronic silencing of corticothalamic layer 6 pyramidal cells affects cortical excitability and tactile behavior

Humanes-Valera, D.; Aguila, J.; Gondzik, V.; Moxon, K.; Schwarz, M. K.; Krieger, P.

10.1101/215558 — neuroscience — Posted on 2017-11-07

1332 Anterior temporal lobe morphometry predicts categorization ability

Garcin, B.; Urbanski, M.; Thiebaut de Schotten, M.; Levy, R.; Volle, E.

10.1101/214965 — neuroscience — Posted on 2017-11-07

1333 Multifactorial Dynamics of White Matter Connectivity During Adolescence

Tunc, B.; Parker, D.; Shinohara, R. T.; Elliott, M. A.; Ruparel, K.; Gur, R. E.; Gur, R. C.; Verma, R.

10.1101/215152 — neuroscience — Posted on 2017-11-07

1334 Paternal grandparental exposure to crop failure or surfeit during a childhood slow growth period and epigenetic marks on third generational growth-, glucoregulatory and stress genes

Bygren, L. O.; Muller, P.; Brodin, D.; Kaati, G.; Kral, J. G.

10.1101/215467 — genomics — Posted on 2017-11-07

1335 Non-invasive measurement of mRNA decay reveals translation initiation as the major determinant of mRNA stability

Chan, L. Y.; Mugler, C. F.; Heinrich, S.; Vallotton, P.; Weis, K.

10.1101/214775 — genetics — Posted on 2017-11-07

1336 Meiosis leads to pervasive segregation distortion and copy-number variation in accessory chromosomes of the wheat pathogen Zymoseptoria tritici

Fouche, S.; Plissonneau, C.; McDonald, B. A.; Croll, D.

10.1101/214882 — evolutionary biology — Posted on 2017-11-07

1337 The Function of the COPII Gene Paralogs SEC23A and SEC23B Are Interchangeable In Vivo

Khoriaty, R.; Hesketh, G.; Bernard, A.; Weyand, A. C.; Mellacheruvu, D.; Zhu, G.; Hoenerhoff, M. J.; McGee, B.; Everett, L.; Adams, E. J.; Zhang, B.; Saunders, T.; Nesvizhskii, A.; Klionsky, D. J.; Shavit, J. A.; Gingras, A.-C.; Ginsburg, D.

10.1101/215160 — evolutionary biology — Posted on 2017-11-07

1338 Cobwebbing in the city: urbanization-driven shifts in body-size dependent behaviours are decoupled from body size in an orb-web spider

Dahirel, M.; De Cock, M.; Bonte, D.

10.1101/214924 — ecology — Posted on 2017-11-07

1339 New Cell Fate Potentials and Switching Kinetics Uncovered in a Classic Bistable Genetic Switch

Fang, X.; Liu, Q.; Bohrer, C.; Hensel, Z.; Han, W.; Wang, J.; Xiao, J.

10.1101/215061 — biophysics — Posted on 2017-11-07

1340 ReprDB and panDB: minimalist databases with maximal microbial representation

Zhou, W.; Gay, N.; Oh, J.

10.1101/214916 — bioinformatics — Posted on 2017-11-07

1341 Predicting Cancer Drug Response Using a Recommender System

Suphavilai, C.; Bertrand, D.; Nagarajan, N.

10.1101/215327 — bioinformatics — Posted on 2017-11-07

1342 Split personality of Aluminum Activated Malate Transporter family proteins: facilitation of both GABA and malate transport

Ramesh, S. A.; Kamran, M.; Sullivan, W.; Chirkova, L.; Okamoto, M.; Degryse, F.; McLaughlin, M.; Gilliham, M.; Tyerman, S. D.

10.1101/215335 — plant biology — Posted on 2017-11-07

1343 JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states

Handoko, L.; Kaczkowski, B.; Hon, C.-C.; Lizio, M.; Wakamori, M.; Matsuda, T.; Ito, T.; Jeyamohan, P.; Sato, Y.; Sakamoto, K.; Yokoyama, S.; Kimura, H.; Minoda, A.; Umehara, T.

10.1101/215442 — molecular biology — Posted on 2017-11-07

1344 Loss of function, missense, and intronic variants in NOTCH1 confer different risks for left ventricular outflow tract obstructive heart defects in two European cohorts

Helle, E.; Cordova-Palomera, A.; Ojala, T.; Saha, P.; Potiny, P.; Gustafsson, S.; Ingelsson, E.; Bamshad, M.; Nickerson, D.; Chong, J. X.; University of Washington Center for Mendelian Geno, ; Ashley, E.; Priest, J. R.

10.1101/215301 — genetics — Posted on 2017-11-07

1345 Stoichiometry and compositional plasticity of the yeast nuclear pore complex revealed by quantitative fluorescence microscopy

Rajoo, S.; Vallotton, P.; Onischenko, E.; Weis, K.

10.1101/215376 — cell biology — Posted on 2017-11-07

1346 Inferring amino acid interactions underlying protein function

Salinas, V. H.; Ranganathan, R.

10.1101/215368 — biochemistry — Posted on 2017-11-07

1347 Discovery of the Quiescent Body that Functions as a Biological Timer for Growth Resumption of Non-growing Bacterial Cells

Yu, J.; Liu, Y.; Yin, H.; Chang, Z.

10.1101/107466 — microbiology — Posted on 2017-11-07

1348 A small subset of NLR genes drives local adaptation to pathogens in wild tomato

Stam, R.; Silva-Arias, G. A.; Nosenko, T.; Scheikl, D.; Hörger, A. C.; Stephan, W.; Haberer, G.; Tellier, A.

10.1101/210559 — evolutionary biology — Posted on 2017-11-07

1349 The Na+(K+)/H+ exchanger Nhx1 controls multivesicular body-vacuolar lysosome fusion

Karim, M. A.; Brett, C.

10.1101/170175 — cell biology — Posted on 2017-11-07

1350 Emerging Electrical Properties of Graphene incorporated Photosynthetic Biofilms

Ray, S.; Sen, S.; Das, A.; Bose, A.; Bhattacharyya, A.; Das, A.; Chattopadhyay, S.; Patra, H. K.; Singha, S.; Singha, A.; Dasgupta, A. K.

10.1101/132225 — biophysics — Posted on 2017-11-07

1351 Dynein dynamics at the microtubule plus-ends and cortex during division in the C. elegans zygote

Rodriguez-Garcia, R.; Chesneau, L.; Pastezeur, S.; Roul, J.; Tramier, M.; Pecreaux, J.

10.1101/118604 — biophysics — Posted on 2017-11-07

1352 Towards a reliable, automated method of individual alpha frequency (IAF) quantification

Corcoran, A. W.; Alday, P. M.; Schlesewsky, M.; Bornkessel-Schlesewsky, I.

10.1101/176792 — bioinformatics — Posted on 2017-11-07

1353 Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima

Morgunova, E.; Yin, Y.; Das, P. K.; Jolma, A.; Popov, A.; Xu, Y.; Nilsson, L.; Taipale, J.

10.1101/205906 — biochemistry — Posted on 2017-11-07

1354 Network modelling unravels mechanisms of crosstalk between ethylene and salicylate signalling in potato

Ramsak, Z.; Coll, A.; Stare, T.; Tzfadia, O.; Baebler, S.; Van de Peer, Y.; Gruden, K.

10.1101/214940 — systems biology — Posted on 2017-11-06

1355 Promoter activity buffering reduces the fitness cost of misregulation.

Schikora-Tamarit, M. A.; Lopez-Grado i Salinas, G.; Gonzalez Navasa, C.; Calderon, I.; Sas, M.; Carey, L.

10.1101/215186 — systems biology — Posted on 2017-11-06

1356 Isolation of a natural DNA virus of Drosophila melanogaster, and characterisation of host resistance and immune responses

Palmer, W. H.; Medd, N.; Beard, P. M.; Obbard, D. J.

10.1101/215111 — microbiology — Posted on 2017-11-06

1357 Associations between sexual habits, menstrual hygiene practices, demographics and the vaginal microbiome as revealed by Bayesian network analysis

Noyes, N.; Cho, K.-C.; Ravel, J.; Forney, L.; Abdo, Z.

10.1101/211631 — microbiology — Posted on 2017-11-06

1358 PIK3IP1/TrIP restricts activation of T cells through inhibition of PI3K/Akt

Uche, U.; Szymczak-Workman, A. L.; Grebinoski, S.; Piccirillo, A.; D'Cruz, L. M.; Kane, L. P.

10.1101/214981 — immunology — Posted on 2017-11-06

1359 Project Dhaka: Variational Autoencoder for Unmasking Tumor Heterogeneity from Single Cell Genomic Data

Rashid, S.; Shah, S.; Bar-Joseph, Z.; Pandya, R.

10.1101/183863 — genomics — Posted on 2017-11-06

1360 Diallel analysis reveals Mx1-dependent and Mx1-independent effects on response to influenza A virus in mice

Maurizio, P. L.; Ferris, M. T.; Keele, G. R.; Miller, D. R.; Shaw, G. D.; Whitmore, A. C.; West, A.; Morrison, C. R.; Noll, K. E.; Plante, K. S.; Cockrell, A. S.; Threadgill, D. W.; Pardo-Manuel de Villena, F.; Baric, R. S.; Heise, M. T.; Valdar, W.

10.1101/214205 — genetics — Posted on 2017-11-06

1361 Population Differentiation at the HLA Genes

Brandt, D. Y. C.; Cesar, J.; Goudet, J.; Meyer, D.

10.1101/214668 — genetics — Posted on 2017-11-06

1362 vqtl: An R package for Mean-Variance QTL Mapping

Corty, R. W.; Valdar, W.

10.1101/149377 — genetics — Posted on 2017-11-06

Zheng, Y.; Graur, D.; Azevedo, R. B. R.

10.1101/215277 — evolutionary biology — Posted on 2017-11-06

1364 Protection from epidemics is a driving force for evolution of lifespan setpoints

Lidsky, P. V.; Andino, R.

10.1101/215202 — evolutionary biology — Posted on 2017-11-06

1365 Disease implications of animal social network structure: a synthesis across social systems

Sah, P.; Mann, J.; Bansal, S.

10.1101/106633 — epidemiology — Posted on 2017-11-06

1366 Transcriptional Changes of DNA Replication and Repair Factors Over Uveal Melanoma Subtypes

Kucherlapati, M. H.

10.1101/214932 — cancer biology — Posted on 2017-11-06

1367 Whole genome analysis reveals pathogenic potential of multi-drug resistant wastewater Escherichia coli

Mahfouz, N.; Caucci, S.; Achatz, E.; Semmler, T.; Guenther, S.; Berendonk, T.; Schroeder, M.

10.1101/215210 — bioinformatics — Posted on 2017-11-06

1368 DriverPower: Combined burden and functional impact tests for cancer driver discovery

Shuai, S.; Gallinger, S.; Stein, L. D.; PCAWG Drivers and Functional Interpretation Group, ; ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Net,

10.1101/215244 — bioinformatics — Posted on 2017-11-06

1369 Arteria: An automation system for a sequencing core facility

Dahlberg, J.; Hermansson, J.; Sturlaugsson, S.; Larsson, P.

10.1101/214858 — bioinformatics — Posted on 2017-11-06

1370 Toward a Genome Scale Sequence Specific Dynamic Model of Cell-Free Protein Synthesis in Escherichia coli

Horvath, N.; Vilkhovoy, M.; Wayman, J. A.; Calhoun, K.; Swartz, J.; Varner, J.

10.1101/215012 — synthetic biology — Posted on 2017-11-06

1371 On the difficulty to interpret results when animals are singly housed: experimental epilepsy as a prototypical example

Manouze, H.; Ghestem, A.; Poillerat, V.; Bennis, M.; Ba-M'hamed, S.; Benoliel, J.-J.; Becker, C.; Bernard, C.

10.1101/214528 — neuroscience — Posted on 2017-11-06

1372 Transcranial in vivo recording of neural activity in the rodent brain with near-infrared photoacoustic voltage-sensitive dye imaging

Kang, J.; Zhang, H. K.; Kadam, S. D.; Julie, F.; Valentine, H.; Yan, P.; Kang, J. U.; Rahmim, A.; Gjedde, A.; Loew, L. M.; Wong, D. F.; Boctor, E. M.

10.1101/202408 — neuroscience — Posted on 2017-11-06

1373 A novel multi SNP based method for the identification of subspecies and associated lineages and sub-lineages of the Mycobacterium tuberculosis complex by whole genome sequencing

Lipworth, S. I. W.; Jajou, R.; de Neeling, H.; Bradley, P.; van der Hoek, W.; Iqbal, Z.; Smith, G.; Peto, T.; Crook, D.; Walker, T. M.; van Soolingen, D.

10.1101/213850 — microbiology — Posted on 2017-11-06

1374 The Evolution Of Covert Signaling

Smaldino, P. E.; Flamson, T. J.; McElreath, R.

10.1101/132407 — evolutionary biology — Posted on 2017-11-06

1375 Minimum requirements for reprogramming and maintaining cell fate in the Arabidopsis root

Drapek, C.; Sparks, E. E.; Marhavy, P.; Andersen, T. G.; Hennacy, J. H.; Geldner, N.; Benfey, P. N.

10.1101/214957 — developmental biology — Posted on 2017-11-06

1376 PI(4,5)P2 forms dynamic cortical structures and directs actin distribution and cell polarity in C. elegans embryos

Scholze, M. J.; Barbieux, K. S.; De Simone, A.; Boumasmoud, M.; Suess, C. C. N.; Wang, R.; Gonczy, P.

10.1101/215079 — developmental biology — Posted on 2017-11-06

1377 FGIN-1-27, an agonist at translocator protein 18 kDa (TSPO), produces anti-anxiety and anti-panic effects in non-mammalian models

Cueto-Escobedo, J.; Rodriguez-Landa, J. F.; Maximino, C.

10.1101/056507 — pharmacology and toxicology — Posted on 2017-11-06

1378 Fronto-parietal Organization for Response Times in Inhibition of Return: The FORTIOR Model

Seidel Malkinson, T.; Bartolomeo, P.

10.1101/134163 — neuroscience — Posted on 2017-11-06

1379 Decoding sequence-level information to predict membrane protein expression

Saladi, S. M.; Javed, N.; Mueller, A.; Clemons, W. M.

10.1101/098673 — biophysics — Posted on 2017-11-06

1380 Multivariate pattern analysis of fMRI data for imaginary and real colours in grapheme-colour synaesthesia

Ruiz, M. J.; Dojat, M.; Hupe, J.-M.

10.1101/214809 — neuroscience — Posted on 2017-11-06

1381 Temporal coupling of field potentials and action potentials in the neocortex

Watson, B. O.; Ding, M.; Buzsaki, G.

10.1101/214650 — neuroscience — Posted on 2017-11-06

1382 Molecular identification of stone loaches of Choman River system, Tigris Basin, based on the Cytochrome b gene with an overview of the Cobitoidea Superfamily

Ghaderi, E.; Farahmand, H.; Bahrami Kamangar, B.; Nematollahi, M. A.

10.1101/210963 — molecular biology — Posted on 2017-11-06

1383 Towards sustainable bioplastic production in resource limited environments using the photoferroautotrophic and photoelectroautotrophic bacterium Rhodopseudomonas palustris TIE-1

Ranaivoarisoa, T. O.; Rengasamy, K.; Guzman, M. S.; Singh, R.; Bose, A.

10.1101/214551 — microbiology — Posted on 2017-11-06

1384 The kinetoplastid-infecting Bodo saltans virus (BsV), a window into the most abundant giant viruses in the sea

Deeg, C. M.; Chow, C.-E. T.; Suttle, C. A.

10.1101/214536 — genomics — Posted on 2017-11-06

1385 Removing unwanted variation between samples in Hi-C experiments

Fletez-Brant, K.; Qiu, Y.; Gorkin, D. U.; Hu, M.; Hansen, K. D.

10.1101/214361 — genomics — Posted on 2017-11-06

1386 Genome-Wide Identification of Early-Firing Human Replication Origins by Optical Replication Mapping

Klein, K.; Wang, W.; Borrman, T.; Chan, S.; Zhang, D.; Weng, Z.; Hastie, A.; Chen, C.; Gilbert, D. M.; Rhind, N.

10.1101/214841 — genomics — Posted on 2017-11-06

1387 A common allele in FGF21 associated with preference for sugar consumption lowers body fat in the lower body and increases blood pressure

Frayling, T. M.; Beaumont, R.; Jones, S. E.; Yaghootkar, H.; Tuke, M. A.; Ruth, K. S.; Casanova, F.; West, B.; Locke, J.; Sharp, S.; Jie, Y.; Thompson, W. D.; Harrison, J. W.; Lindgren, C. M.; Grarup, N.; Murray, A.; Freathy, R. M.; Weedon, M. N.; Tyrrell, J.; Wood, A. R.

10.1101/214700 — genetics — Posted on 2017-11-06

1388 Mitochondrial genomes of the regionally extinct Nittany Lion (Puma concolor from Pennsylvania)

Evanitsky, M. N.; George, R. J.; Johnson, S.; Dowell, S.; Perry, G. H.

10.1101/214510 — ecology — Posted on 2017-11-06

1389 Butterflyfishes as a System for Investigating Pair Bonding

Nowicki, J.; O'Connell, L.; Cowman, P.; Walker, S.; Coker, D.; Pratchett, M.

10.1101/214544 — ecology — Posted on 2017-11-06

1390 Combined Androgen Administration and HDAC Inhibition in Experimental Cancer Cachexia

Tseng, Y.-C.; Liva, S. G.; Dauki, A. M.; Henderson, S. E.; Kuo, Y.-C.; Benedict, J. A.; Kulp, S. K.; Bekaii-Saab, T.; Chen, C.-S.; Coss, C. C.

10.1101/214155 — cancer biology — Posted on 2017-11-06

1391 Evolutionary dynamics and molecular features of intra-tumor heterogeneity

Raynaud, F.; Mina, M.; Ciriello, G.

10.1101/214791 — cancer biology — Posted on 2017-11-06

1392 CalR: A Web-based Analysis Tool for Indirect Calorimetry Experiments

Mina, A. I.; LeClair, R. A.; LeClair, K. B.; Cohen, D. E.; Lantier, L.; Banks, A. S.

10.1101/213967 — bioinformatics — Posted on 2017-11-06

1393 Exploring biological networks in 3D, stereoscopic 3D and immersive 3D with iCAVE

Kalayci, S.; Gumus, Z. H.

10.1101/212126 — bioinformatics — Posted on 2017-11-06

1394 Using experimental data as a voucher for study pre-registration

Mazor, M.; Mazor, N.; Mukamel, R.

10.1101/213439 — scientific communication and education — Posted on 2017-11-06

1395 Synchronous inhibitory pathways create both efficiency and diversity in the retina

Manu, M.; McIntosh, L. T.; Kastner, D. B.; Naecker, B. N.; Baccus, S. A.

10.1101/214569 — neuroscience — Posted on 2017-11-06

1396 Neurobiology of pair bonding in fishes; convergence of neural mechanisms across distant vertebrate lineages

Nowicki, J.; Pratchett, M.; Walker, S.; Coker, D.; O'Connell, L. A.

10.1101/214759 — neuroscience — Posted on 2017-11-06

1397 Evolution of exploitative interactions during diversification in Bacillus subtilis biofilms

Dragos, A.; Lakshmanan, N.; Martin, M.; Horvath, B.; Maroti, G.; Falcon Garcia, C.; Lieleg, O.; Kovacs, A. T.

10.1101/173476 — microbiology — Posted on 2017-11-06

1398 A Polymorphic Residue That Attenuates Interferon Lambda 4 Activity in Hominid Lineages

Bamford, C. G. G.; Aranday-Cortes, E.; Cordeiro Filipe, I.; Sukumar, S.; Mair, D.; da Silva Filipe, A.; Mendoza, J. L.; Garcia, K. C.; Fan, S.; Tishkoff, S. A.; McLauchlan, J.

10.1101/214825 — immunology — Posted on 2017-11-06

1399 Distinct Epigenomic Patterns Are Associated with Haploinsufficiency and Predict Risk Genes of Developmental Disorders

Han, X.; Chen, S.; Flynn, E. D.; Wu, S.; Wintner, D.; Shen, Y.

10.1101/205849 — genomics — Posted on 2017-11-06

1400 Polygenic Adaptation has Impacted Multiple Anthropometric Traits

Berg, J. J.; Zhang, X.; Coop, G.

10.1101/167551 — evolutionary biology — Posted on 2017-11-06

1401 Competitive ability of a tetraploid selfing species (Capsella bursa-pastoris) across its expansion range and comparison with its sister species

Yang, X.; Lascoux, M.; Glemin, S.

10.1101/214866 — evolutionary biology — Posted on 2017-11-06

1402 Early-exposure to new sex pheromone blend alters mate preference in female butterflies and in their offspring

Dion, E.; Pui, L. X.; Monteiro, A.

10.1101/214635 — evolutionary biology — Posted on 2017-11-06

1403 Pair bond endurance promotes cooperative food defense and inhibits conflict in coral reef butterflyfishes

Nowicki, J. P.; Walker, S.; Coker, D.; Hoey, A.; Nicolet, K.; Pratchett, M.

10.1101/214627 — ecology — Posted on 2017-11-06

1404 An optimized pipeline for parallel image-based quantification of gene expression and genotyping after in situ hybridization

Dobrzycki, T.; Krecsmarik, M.; Bonkhofer, F.; Patient, R. K.; Monteiro, R.

10.1101/149591 — developmental biology — Posted on 2017-11-06

1405 Multidimensional quantitative analysis of mRNA expression within intact vertebrate embryos

Trivedi, V.; Choi, H. M. T.; Fraser, S. E.; Pierce, N. A.

10.1101/214619 — developmental biology — Posted on 2017-11-06

1406 Identification of residue pairing in interacting β-strands from a predicted residue contact map

Mao, W.; Wang, T.; Zhang, W.; Gong, H.

10.1101/214643 — bioinformatics — Posted on 2017-11-06

1407 Deep learning accurately predicts estrogen receptor status in breast cancer metabolomics data

Alkawaa, F.; Chaudhary, K.; Garmire, L.

10.1101/214254 — bioinformatics — Posted on 2017-11-06

1408 Quetzal - an open source C++ template library for coalescence-based environmental demogenetic models inference

Becheler, A.; Coron, C.; Dupas, S.

10.1101/214767 — bioinformatics — Posted on 2017-11-06

1409 Integrated molecular and clinical analysis for understanding human disease relationships

Haynes, W.; Vashisht, R.; Vallania, F.; Liu, C.; Gaskin, G. L.; Bongen, E.; Lofgren, S.; Sweeney, T. E.; Utz, P. J.; Shah, N. H.; Khatri, P.

10.1101/214833 — bioinformatics — Posted on 2017-11-06

1410 Comprehensive analysis of mobile genetic elements in the gut microbiome reveals a phylum-level niche-adaptive gene pool

Jiang, X.; Hall, A. B.; Xavier, R. J.; Alm, E. J.

10.1101/214213 — bioinformatics — Posted on 2017-11-06

1411 Community assessment of cancer drug combination screens identifies strategies for synergy prediction

Menden, M. P.; Wang, D.; Guan, Y.; Mason, M.; Szalai, B.; Bulusu, K. C.; Yu, T.; Kang, J.; Jeon, M.; Wolfinger, R.; Nguyen, T.; Zaslavskiy, M.; AstraZeneca-Sanger Drug Combination DREAM Consorti, ; Jang, I. S.; Ghazoui, Z.; Ahsen, M. E.; Vogel, R.; Chaibub Neto, E.; Norman, T.; Tang, E. K.; Garnett, M. J.; Di Veroli, G.; Fawell, S.; Stolovitzky, G.; Guinney, J.; Dry, J. R.; Saez-Rodriguez, J.

10.1101/200451 — bioinformatics — Posted on 2017-11-06

1412 Uncovering cell-free protein expression dynamics by a promoter library with diverse strengths

Galinanes Reyes, S.; Kuruma, Y.; Tsuda, S.

10.1101/214593 — synthetic biology — Posted on 2017-11-06

1413 The Distribution of Bacterial Doubling Times in the Wild

Gibson, B.; Wilson, D.; Feil, E.; Eyre-Walker, A.

10.1101/214783 — microbiology — Posted on 2017-11-06

1414 MaxTiC: Fast Ranking Of A Phylogenetic Tree By Maximum Time Consistency With Lateral Gene Transfers

Chauve, C.; Rafiey, A.; Davin, A. A.; Scornavacca, C.; Veber, P.; Boussau, B.; Szollosi, G.; Daubin, V.; Tannier, E.

10.1101/127548 — evolutionary biology — Posted on 2017-11-06

1415 Genome size variation and species diversity in salamander families

Sclavi, B.; Herrick, J.

10.1101/065425 — evolutionary biology — Posted on 2017-11-06

1416 Spatio-temporal elasticity patterns in extracellular matrix during Hydra morphogenesis

Veschgini, M.; Petersen, H. O.; Abuillan, W.; Rossetti, F. F.; Özbek, S.; Burghammer, M.; Holstein, T. W.; Tanaka, M.

10.1101/214718 — developmental biology — Posted on 2017-11-06

1417 Quantitative methods to investigate the 4D dynamics of heterochromatic repair sites in Drosophila cells

Caridi, C. P.; Delabaere, L.; Tjong, H.; Hopp, H.; Das, D.; Alber, F.; Chiolo, I.

10.1101/214601 — cell biology — Posted on 2017-11-06

1418 Self-oligomerization regulates stability of Survival Motor Neuron (SMN) protein isoforms by sequestering an SCFSlmb degron

Gray, K. M.; Kaifer, K. A.; Baillat, D.; Wen, Y.; Bonacci, T. R.; Ebert, A. D.; Raimer, A. C.; Spring, A. M.; ten Have, S.; Glascock, J. J.; Gupta, K.; Van Duyne, G. D.; Emanuele, M. J.; Lamond, A. I.; Wagner, E. J.; Lorson, C. L.; Matera, A. G.

10.1101/078337 — biochemistry — Posted on 2017-11-06

1419 Dynein dynamics at the microtubule plus-ends and cortex during division in the C. elegans zygote

Rodriguez-Garcia, R.; Chesneau, L.; Pastezeur, S.; Roul, J.; Tramier, M.; Pecreaux, J.

10.1101/118604 — biophysics — Posted on 2017-11-06

1420 The contribution of striatal pseudo-reward prediction errors to value-based decision-making

Mas-Herrero, E.; Sescousse, G.; Cools, R.; Marco-Pallares, J.

10.1101/097873 — neuroscience — Posted on 2017-11-06

1421 Adiposity QTL Adip20 decomposes into at least four loci when dissected using congenic strains

Lin, C.; Fesi, B. D.; Marquis, M.; Bosak, N. P.; Lysenko, A.; Koshnevisan, M. A.; Duke, F. F.; Theodorides, M. L.; Nelson, T. M.; McDaniel, A. H.; Avigdor, M.; Arayata, C. J.; Shaw, L.; Bachmanov, A. A.; Reed, D. R.

10.1101/171777 — genetics — Posted on 2017-11-06

1422 Compositional Inductive Biases in Function Learning

Schulz, E.; Tenenbaum, J. B.; Duvenaud, D.; Speekenbrink, M.; Gershman, S. J.

10.1101/091298 — animal behavior and cognition — Posted on 2017-11-06

1423 An evaluation of the efficacy, reliability, and sensitivity of motion correction strategies for resting-state functional MRI

Parkes, L.; Fulcher, B. D.; Yucel, M.; Fornito, A.

10.1101/156380 — neuroscience — Posted on 2017-11-05

1424 MatClassRSA: A Matlab toolbox for M/EEG classification and visualization of proximity matrices

Wang, B. C.; Norcia, A. M.; Kaneshiro, B.

10.1101/194563 — neuroscience — Posted on 2017-11-05

1425 Periodic variation of mutation rates in bacterial genomes associated with replication timing

Dillon, M. M.; Sung, W.; Lynch, M.; Cooper, V. S.

10.1101/195818 — genetics — Posted on 2017-11-05

1426 Ancient genomic variation underlies repeated ecological adaptation in young stickleback populations

Nelson, T. C.; Cresko, W. A.

10.1101/167981 — evolutionary biology — Posted on 2017-11-05

1427 Label-free quantitative screening of breast tissue using Spatial Light Interference Microscopy (SLIM)

Majeed, H.; Nguyen, T. H.; Kandel, M. E.; Kadjdacsy-Balla, A.; Popescu, G.

10.1101/214502 — pathology — Posted on 2017-11-05

1428 Causal Mapping of Emotion Networks in the Human Brain: Framework and Preliminary Findings

Dubois, J.; Oya, H.; Tyszka, J. M.; Howard, M.; Eberhardt, F.; Adolphs, R.

10.1101/214486 — neuroscience — Posted on 2017-11-05

1429 Kombucha as a model system for multispecies microbial cooperation: theoretical promise, methodological challenges and new solutions ‘in solution’

May, A. N.; Medina, J.; Alcock, J.; Maley, C.; Aktipis, A.

10.1101/214478 — microbiology — Posted on 2017-11-05

1430 EditR: A novel base editing quantification software using Sanger sequencing

Kluesner, M.; Nedveck, D.; Lahr, W.; Garbe, J.; Abrahante, J.; Webber, B.; Moriarity, B.

10.1101/213496 — genetics — Posted on 2017-11-05

1431 Accurate Discrimination of 23 Major Cancer Types via Whole Genome Somatic Mutation Patterns

Jiao, W.; Polak, P.; Karlic, R.; Getz, G.; Stein, L. D.; PCAWG Pathology and Clinical Correlates Working Gr, ; ICGC/TCGA Pan-cancer Analysis of Whole Genomes Net,

10.1101/214494 — cancer biology — Posted on 2017-11-05

1432 APR-246 reactivates mutant p53 by targeting cysteines 124 and 277

Zhang, Q.; Bykov, V. J. N.; Wiman, K. G.; Zawacka-Pankau, J.

10.1101/214049 — cancer biology — Posted on 2017-11-05

1433 Subtle alteration in microRNA dynamics accounts for differential nature of cellular proliferation

Sengupta, D.; Govindaraj, V.; Kar, S.

10.1101/214429 — systems biology — Posted on 2017-11-05

1434 Abnormal reward prediction error signalling in antipsychotic naive individuals with first episode psychosis or clinical risk for psychosis

Ermakova, A. O.; Knolle, F.; Justicia, A.; Bullmore, E. T.; Jones, P. B.; Robbins, T. W.; Fletcher, P. C.; Murray, G. K.

10.1101/214437 — neuroscience — Posted on 2017-11-05

1435 Receptor guanylyl cyclase C confers protection during oral Salmonella Typhimurium infection by attenuating ileal damage and enhancing cytokine and antimicrobial peptide production

Majumdar, S.; Mishra, V.; Nandi, S.; Abdullah, M.; Barman, A.; Raghavan, A.; Nandi, D.; Visweswariah, S. S.

10.1101/214163 — microbiology — Posted on 2017-11-05

1436 A novel multi SNP based method for identifying subspecies and associated lineages and sub-lineages of the Mycobacterium tuberculosis complex by whole genome sequencing

Lipworth, S. I.; Jajou, R.; de Neeling, H.; Bradley, P.; van der Hoek, W.; Iqbal, Z.; Smith, G.; Peto, T.; Crook, D.; Walker, T. M.; van Soolingen, D.

10.1101/213850 — microbiology — Posted on 2017-11-05

1437 YlmD and YlmE are required for correct sporulation-specific cell division in Streptomyces coelicolor A3(2)

Zhang, L.; Willemse, J.; Hoskisson, P. A.; van Wezel, G.

10.1101/214072 — microbiology — Posted on 2017-11-05

1438 Divalent metal cations potentiate the predatory capacity of amoeba for Cryptococcus neoformans

Fu, M. S.; Casadevall, A.

10.1101/214460 — microbiology — Posted on 2017-11-05

1439 HiMAP: robust Phylogenomics from Highly Multiplexed Amplicon sequencing

Dupuis, J. R.; Bremer, F. T.; Kauwe, A.; San Jose, M.; Leblanc, L.; Rubinoff, D.; Geib, S.

10.1101/213454 — genomics — Posted on 2017-11-05

1440 Atf3 links loss of epithelial polarity to defects in cell differentiation and cytoarchitecture

Donohoe, C. D.; Correia, A.; Csordas, G.; Jindra, M.; Klein, C.; Habermann, B.; Uhlirova, M.

10.1101/212969 — genetics — Posted on 2017-11-05

1441 Imaging-Genomics Study Of Head-Neck Squamous Cell Carcinoma: Associations Between Radiomic Phenotypes And Genomic Mechanisms Via Integration Of TCGA And TCIA

Zhu, Y.; Mohamed, A. S.; Lai, S. Y.; Yang, S.; Kanwar, A.; Wei, L.; Kamal, M.; Sengupta, S.; Elhalawani, H.; Skinner, H.; Mackin, D. S.; Shiao, J.; Messer, J.; Wong, A.; Ding, Y.; Zhang, J.; Court, L.; Ji, Y.; Fuller, C. D.

10.1101/214312 — cancer biology — Posted on 2017-11-05

1442 Theory of site-specific DNA-protein interactions in the presence of nucleosome roadblocks

Murugan, R.

10.1101/214387 — biophysics — Posted on 2017-11-05

1443 TNER: A Novel Bayesian Background Error Suppression Method for Mutation Detection in Circulating Tumor DNA

Deng, S.; Lira, M.; Huang, D.; Wang, K.; Valdez, C.; Kinong, J.; Rejto, P. A.; Bienkowska, J. R.; Hardwick, J.; Xie, T.

10.1101/214379 — bioinformatics — Posted on 2017-11-05

1444 Boosting Gene Expression Clustering with System-Wide Biological Information: A Robust Autoencoder Approach

Cui, H.; Zhou, C.; Dai, X.; Liang, Y.; Paffenroth, R.; Korkin, D.

10.1101/214122 — bioinformatics — Posted on 2017-11-05

1445 TCGA-Assembler 2: Software Pipeline for Retrieval and Processing of TCGA/CPTAC Data

Wei, L.; Jin, Z.; Yang, S.; Xu, Y.; Zhu, Y.; Ji, Y.

10.1101/214320 — bioinformatics — Posted on 2017-11-05

1446 TaxAss: Leveraging Custom Databases Achieves Fine-Scale Taxonomic Resolution

Rohwer, R. R.; Hamilton, J. J.; Newton, R. J.; McMahon, K. D.

10.1101/214288 — bioinformatics — Posted on 2017-11-05

1447 Binless normalization of Hi-C data provides significant interaction and difference detection independently of resolution

Spill, Y. G.; Castillo, D.; Marti-Renom, M. A.

10.1101/214403 — bioinformatics — Posted on 2017-11-05

1448 A theta rhythm in awake macaque visual cortex and its attentional modulation

Spyropoulos, G.; Bosman, C. A.; Fries, P.

10.1101/117804 — neuroscience — Posted on 2017-11-05

1449 A theory of multineuronal dimensionality, dynamics and measurement

Gao, P.; Trautmann, E.; Yu, B. M.; Santhanam, G.; Ryu, S.; Shenoy, K.; Ganguli, S.

10.1101/214262 — neuroscience — Posted on 2017-11-05

1450 Variational Autoencoder: An Unsupervised Model for Modeling and Decoding fMRI Activity in Visual Cortex

Han, K.; Wen, H.; Shi, J.; Lu, K.-H.; Zhang, Y.; Liu, Z.

10.1101/214247 — neuroscience — Posted on 2017-11-05

1451 Behavior state-dependent lateralization of dorsal dentate gyrus c-Fos expression in mice

Jordan, J. T.; Pytte, C. L.

10.1101/214239 — neuroscience — Posted on 2017-11-05

1452 Pydigree: a python library for manipulation and forward-time simulation and of genetic datasets

Hicks, J. E.

10.1101/213413 — bioinformatics — Posted on 2017-11-05

1453 Processive movement of actin by biased polymerization: a new paradigm of axonal transport

Chakrabarty, N.; Dubey, P.; Tang, Y.; Ganguly, A.; Ladt, K.; Leterrier, C.; Jung, P.; Roy, S.

10.1101/212449 — neuroscience — Posted on 2017-11-04

1454 Pathologic gene network rewiring implicates PPP1R3A as a central cardioprotective factor in pressure overload heart failure

Cordero, P.; Parikh, V. N.; Erbilgin, A.; Shang, C.; Smith, K. S.; Dewey, F.; Zaleta, K.; Morley, M.; Brandimarto, J.; Glazer, N.; Pavlovic, A.; Moravec, C.; Tang, W. H.; Viterna, J.; Malloy, C.; Hannenhalli, S.; Li, H.; Ritter, S.; Li, M.; Connolly, A.; Hakonarson, H.; Lusis, A. J.; Margulies, K. B.; Depaoli-Roach, A. A.; Montgomery, S.; Wheeler, M. T.; Cappola, T.; Ashley, E. A.

10.1101/038174 — genomics — Posted on 2017-11-04

1455 Cysteine proteases of human hookworm Necator Americanus as virulence factors and implications for drug design with anti-heparin and heparin analogs: A bioinformatics study

Banerjee, A.; Abagyan, R.

10.1101/116921 — bioinformatics — Posted on 2017-11-04

1456 Using experimental data as a voucher for study pre-registration

Mazor, M.; Mazor, N.; Mukamel, R.

10.1101/213439 — scientific communication and education — Posted on 2017-11-04

1457 Percent amplitude of fluctuation: a simple measure for resting-state fMRI signal at single voxel level

Jia, X.-Z.; Ji, G.-J.; Liao, W.; Lv, Y.-T.; Wang, J.; Wang, Z.; Zhang, H.; Liu, D.-Q.; Zang, Y.-F.

10.1101/214098 — neuroscience — Posted on 2017-11-04

1458 A mid-level organization of the ventral stream

Long, B.; Yu, C.-P.; Konkle, T.

10.1101/213934 — neuroscience — Posted on 2017-11-04

1459 Two-stage adaptation of inhibition mediates predictive sensitization in the retina

Kastner, D. B.; Panagiotakos, G.; Ozuysal, Y.; Baccus, S. A.

10.1101/214130 — neuroscience — Posted on 2017-11-04

1460 Running reduces firing but improves coding in rodent higher-order visual cortex

Christensen, A. J.; Pillow, J. W.

10.1101/214007 — neuroscience — Posted on 2017-11-04

1461 Prediction error induced motor contagions in human behaviors

Ikegami, T.; Ganesh, G.; Takeuchi, T.; Nakamoto, H.

10.1101/214056 — neuroscience — Posted on 2017-11-04

1462 Enhanced deviant responses in patterned relative to random sound sequences

Southwell, R.; Chait, M.

10.1101/214031 — neuroscience — Posted on 2017-11-04

1463 YlmD and YlmE are required for correct sporulation-specific cell division in Streptomyces coelicolor A3(2)

Zhang, L.; Willemse, J.; Hosksson, P. A.; van Wezel, G.

10.1101/214072 — microbiology — Posted on 2017-11-04

1464 Whole-genome sequencing analysis of genomic copy number variation (CNV) using low-coverage and paired-end strategies is highly efficient and outperforms array based CNV analysis

Zhou, B.; Ho, S. S.; Zhang, X.; Pattni, R.; Haraksingh, R. R.; Urban, A. E.

10.1101/192310 — genomics — Posted on 2017-11-04

1465 Interdependent and separable functions of C. elegans MRN-C complex members couple formation and repair of meiotic DSBs

Girard, C.; Roelens, B.; Zawadzki, K. A.; Villeneuve, A. M.

10.1101/214015 — genetics — Posted on 2017-11-04

1466 Predicting Global Forest Reforestation Potential

Crowther, T. W.; Glick, H. B.; Maynard, D. S.; Ashley-Cantello, W.; Evans, T.; Routh, D.

10.1101/210062 — ecology — Posted on 2017-11-04

1467 The Use of Biogeographical Patterns to Assess Key Adaptations in Two Families of Birds

Halloway, A.; Whelan, C. J.; Sekercioglu, C. H.; Brown, J. S.

10.1101/214148 — ecology — Posted on 2017-11-04

1468 Cohesin facilitates zygotic genome activation in zebrafish

Meier, M.; Grant, J.; Dowdle, A.; Thomas, A.; Gerton, J. E.; Collas, P.; O'Sullivan, J. M.; Horsfield, J. A.

10.1101/214023 — developmental biology — Posted on 2017-11-04

1469 Reconciling the clk-1 and aging paradox and categorizing lifespan curves by taking individual specificity into account

Ren, Y.; Zhang, C.; Guo, W.; Zhang, C.

10.1101/213512 — cell biology — Posted on 2017-11-04

1470 Fractional Dynamics in Bioscience and Biomedicine and the Physics of Cancer

Nasrolahpour, H.

10.1101/214197 — biophysics — Posted on 2017-11-04

1471 CalR: A Web-based Analysis Tool for Indirect Calorimetry Experiments

Mina, A. I.; LeClair, R. A.; LeClair, K. B.; Cohen, D. E.; Lantier, L.; Banks, A. S.

10.1101/213967 — bioinformatics — Posted on 2017-11-04

1472 Creating ethnicity-specific reference intervals for lab tests from EHR data

Rappoport, N.; Paik, H.; Oskotsky, B.; Tor, R.; Ziv, E.; Zaitlen, N.; Butte, A. J.

10.1101/213892 — bioinformatics — Posted on 2017-11-04

1473 Chemical genomic guided engineering of gamma-valerolactone tolerant yeast

Bottoms, S.; Dickinson, Q.; McGee, M.; Hinchman, L.; Higbee, A.; Hebert, A.; Serate, J.; Xie, D.; Zhang, Y.; Coon, J. J.; Myers, C. L.; Landick, R.; Piotrowski, J. S.

10.1101/213991 — bioengineering — Posted on 2017-11-04

1474 Squid Ring Teeth Coated Mesh Improves Abdominal Wall Repair

Leberfinger, A.; Hospodiuk, M.; Pena-Francesch, A.; Ayan, B.; Ozbolat, V.; Koduru, S.; Ozbolat, I.; Demirel, M. C.; Ravnic, D.

10.1101/214114 — bioengineering — Posted on 2017-11-04

1475 Characterising the short-term habituation of event-related evoked potentials

Mancini, F.; Pepe, A.; Di Stefano, G.; Mouraux, A.; Iannetti, G. D.

10.1101/153387 — neuroscience — Posted on 2017-11-04

1476 Meta-analysis of massive parallel reporter assay enables functional regulatory elements prediction

Kreimer, A.; Yan, Z.; Ahituv, N.; Yosef, N.

10.1101/202002 — genomics — Posted on 2017-11-03

1477 90-90-90, epidemic control, and ending AIDS: review of global situation and recommendations

Granich, R.; Williams, B. G.; Gupta, S.; Zuniga, J. M.

10.1101/196972 — epidemiology — Posted on 2017-11-03

1478 Game theoretic consideration of transgenic bacteria in the human gut microbiota as a pro-biotic prophylactic for metabolic syndrome

Ibrahim, A.; Smith, J.

10.1101/206227 — bioengineering — Posted on 2017-11-03

1479 Combinatorial Drug Discovery in Nanoliter Droplets

Kulesa, A.; Kehe, J.; Hurtado, J.; Tawde, P.; Blainey, P. C.

10.1101/210492 — bioengineering — Posted on 2017-11-03

1480 Delineating the macroscale areal organization of the macaque cortex in vivo

Xu, T.; Falchier, A.; Sullivan, E.; Linn, G.; Ramirez, J.; Ross, D.; Feczko, E.; Opitz, A.; Bagley, J.; Sturgeon, D.; Earl, E.; Miranda-Domingue, O.; Perrone, A.; Craddock, C.; Schroeder, C.; Colcombe, S.; Fair, D.; Milham, M.

10.1101/155952 — neuroscience — Posted on 2017-11-03

1481 Experience-dependent neuroplasticity of the developing hypothalamus: integrative epigenomic approaches

Vogel Ciernia, A.; Laufer, B. I.; Dunaway, K. W.; Mordaunt, C. E.; Coulson, R. L.; Totah, T. S.; Stolzenberg, D. S.; Frahm, J. C.; Singh-Taylor, A.; Baram, T. Z.; LaSalle, J. M.; Yasui, D. H.

10.1101/191791 — genomics — Posted on 2017-11-03

1482 Towards a reliable, automated method of individual alpha frequency (IAF) quantification

Corcoran, A. W.; Alday, P. M.; Schlesewsky, M.; Bornkessel-Schlesewsky, I.

10.1101/176792 — bioinformatics — Posted on 2017-11-03

1483 Evidence for loss and adaptive reacquisition of alcoholic fermentation in an early-derived fructophilic yeast lineage

Goncalves, C.; Wisecaver, J. H.; Salema-Oom, M.; Leandro, M. J.; Shen, X.-X.; Peris, D.; Hittinger, C. T.; Rokas, A.; Goncalves, P.

10.1101/213686 — genomics — Posted on 2017-11-03

1484 Profiling of accessible chromatin regions across multiple plant species and cell types reveals common gene regulatory principles and new control modules

Maher, K. A.; Bajic, M.; Kajala, K.; Reynoso, M.; Pauluzzi, G.; West, D. A.; Zumstein, K.; Woodhouse, M.; Bubb, K.; Dorrity, M.; Queitsch, C.; Bailey-Serres, J.; Sinha, N.; Brady, S. M.; Deal, R. B.

10.1101/167932 — plant biology — Posted on 2017-11-03

1485 Learning the pattern of epistasis linking genotype and phenotype in a protein

Poelwijk, F. J.; Socolich, M.; Ranganathan, R.

10.1101/213835 — systems biology — Posted on 2017-11-03

1486 Chromatin accessibility changes between Arabidopsis stem cells and mesophyll cells illuminate cell type-specific transcription factor networks

Sijacic, P.; Bajic, M.; McKinney, E. C.; Meagher, R. B.; Deal, R. B.

10.1101/213900 — plant biology — Posted on 2017-11-03

1487 Coherent olfactory bulb gamma oscillations arise from coupling independent columnar oscillators

Peace, S. T.; Johnson, B. C.; Li, G.; Kaiser, M. E.; Fukunaga, I.; Schaefer, A. T.; Molnar, A. C.; Cleland, T. A.

10.1101/213827 — neuroscience — Posted on 2017-11-03

1488 An eutherian intronic sequence gave rise to a major satellite DNA in Platyrrhini

Valeri, M. P.; Dias, G. B.; Pereira, V. S.; Kuhn, G. C. S.; Svartman, M.

10.1101/213868 — genomics — Posted on 2017-11-03

1489 Sensitivity to sequencing depth in single-cell cancer genomics

Alves, J. M.; Posada, D.

10.1101/213744 — genomics — Posted on 2017-11-03

1490 A phase separated organelle at the root of motile ciliopathy

Huizar, R.; Lee, C.; Boulgakov, A.; Horani, A.; Tu, F.; Drew, K.; Marcotte, E.; Brody, S.; Wallingford, J.

10.1101/213793 — cell biology — Posted on 2017-11-03

1491 Arabidopsis HIPP27 is a host susceptibility gene for the beet cyst nematode Heterodera schachtii

Radakovic, Z. S.; Anjam, M. S.; Escobar, E.; Chopra, D.; Cabrera, J.; Silva, A. C.; Escobar, C.; Sobczak, M.; Grundler, F. M. W.; Siddique, S.

10.1101/208132 — plant biology — Posted on 2017-11-03

1492 Distinct types of short open reading frames are translated in plant cells

Fesenko, I.; Kirov, I.; Kniazev, A.; Khazigaleeva, R.; Lazarev, V.; Kharlampieva, D.; Grafskaia, E.; Zgoda, V.; Butenko, I.; Arapidi, G.; Mamaeva, A.; Ivanov, V.; Govorun, V.

10.1101/213736 — plant biology — Posted on 2017-11-03

1493 The Hallucination Machine: A Deep-Dream VR platform for Studying the Phenomenology of Visual Hallucinations

Suzuki, K.; Roseboom, W.; Schwartzman, D. J.; Seth, A. K.

10.1101/213751 — neuroscience — Posted on 2017-11-03

1494 A proposed chaperone of the bacterial type VI secretion system functions to constrain a self-identity protein

Zepeda-Rivera, M. A.; Saak, C. C.; Gibbs, K. A.

10.1101/213785 — microbiology — Posted on 2017-11-03

1495 Conductive particles enable syntrophic acetate oxidation between Geobacter and Methanosarcina from coastal sediments

Rotaru, A.-E.; Stryhanyuk, H.; Calabrese, F.; Musat, F.; Shrestha, P. M.; Weber, H. S.; Snoeyenbos-West, O. L. O.; Hall, P. O. J.; Richnow, H. H.; Musat, N.; Thamdrup, B.

10.1101/213843 — microbiology — Posted on 2017-11-03

1496 Technology-independent estimation of cell type composition using differentially methylated regions

Hicks, S. C.; Irizarry, R. A.

10.1101/213769 — genomics — Posted on 2017-11-03

1497 High-throughput single-cell DNA sequencing of AML tumors with droplet microfluidics

Pellegrino, M.; Sciambi, A.; Treusch, S.; Gokhale, K.; Jacob, J.; Chen, T. X.; Oldham, W.; Durruthy-Durruthy, R.; Patel, K.; Matthews, J.; Kantarjian, H.; Futreal, P. A.; Jones, K. W.; Takahashi, K.; Eastburn, D. J.

10.1101/203158 — genomics — Posted on 2017-11-03

1498 Multivariate analysis of the cotton seed ionome reveals integrated genetic signatures of abiotic stress response

Pauli, D.; Ziegler, G.; Ren, M.; Jenks, M. A.; Hunsaker, D. J.; Zhang, M.; Baxter, I.; Gore, M. A.

10.1101/213777 — genetics — Posted on 2017-11-03

1499 Genetic conflict with a parasitic nematode disrupts the legume-rhizobia mutualism

Wood, C. W.; Pilkington, B.; Vaidya, P.; Biel, C.; Stinchcombe, J.

10.1101/213876 — evolutionary biology — Posted on 2017-11-03

1500 Loter: A software package to infer local ancestry for a wide range of species

Dias-Alves, T.; Mairal, J.; Blum, M. G. B.

10.1101/213728 — bioinformatics — Posted on 2017-11-03

1501 Spatially varying cis-regulatory divergence in Drosophila embryos elucidates cis-regulatory logic

Combs, P. A.; Fraser, H. B.

10.1101/175059 — systems biology — Posted on 2017-11-03

1502 Modelling GxE with historical weather information improves genomic prediction in new environments

Gillberg, J.; Marttinen, P.; Mamitsuka, H.; Kaski, S.

10.1101/213231 — bioinformatics — Posted on 2017-11-03

1503 Stochastic dynamics of an epidemics with recurrent spillovers from an endemic reservoir

Voinson, M.; Alvergne, A.; Billiard, S.; Smadi, C.

10.1101/213579 — epidemiology — Posted on 2017-11-03

1504 Identification of an epitope of limited variability under strong immune selection in the haemagglutinin head domain of H1N1 influenza

Thompson, C. P.; Lourenco, J.; Walters, A. A.; Obolski, U.; Edmans, M.; Palmer, D. S.; Kooblall, K.; Carnell, G. W.; O Connor, D.; Bowden, T. A.; Pybus, O. G.; Pollard, A. J.; Temperton, N. J.; Lambe, T.; Gilbert, S. G.; Gupta, S.

10.1101/212845 — epidemiology — Posted on 2017-11-03

1505 EpiModel: An R Package for Mathematical Modeling of Infectious Disease over Networks

Jenness, S.; Goodreau, S. M.; Morris, M.

10.1101/213009 — epidemiology — Posted on 2017-11-03

1506 Exploring variation in human papillomavirus vaccination uptake: multi-level spatial analysis

Riesen, M.; Konstantinoudis, G.; Lang, P.; Low, N.; Hatz, C.; Maeusezahl, M.; Spaar, A.; Buehlmann, M.; Spycher, B. D.; Althaus, C. L.

10.1101/210260 — epidemiology — Posted on 2017-11-03

1507 Influence of APOA5 locus on the treatment efficacy of three statins: evidence from a randomized pilot study in Chinese subjects

Hua, S.; Ma, C.; Zhang, J.; Li, J.; Wu, W.; Xu, N.; Luo, G.; Zhao, J.

10.1101/213629 — clinical trials — Posted on 2017-11-03

1508 GrigoraSNPs: Optimized HTS DNA Forensic SNP Analysis

Ricke, D. O.; Shcherbina, A.; Michaleas, A.; Fremont-Smith, P.

10.1101/173716 — bioinformatics — Posted on 2017-11-03

1509 Cadmium exposure inhibits branching morphogenesis and causes alterations consistent with HIF-1α inhibition in human primary breast organoids

Rocco, S. A.; Koneva, L.; Middleton, L. Y. M.; Thong, T.; Solanki, S.; Karram, S.; Nambunmee, K.; Harris, C.; Rozek, L. S.; Sartor, M. A.; Shah, Y. M.; Colacino, J.

10.1101/208157 — pharmacology and toxicology — Posted on 2017-11-03

1510 Propofol-Induced Unresponsiveness is Associated with Impaired Feedforward Connectivity in the Cortical Hierarchy

Sanders, R. D.; Banks, M. I.; Darracq, M.; Moran, R.; Sleigh, J.; Gosseries, O.; Bonhomme, V.; Brichant, J.-F.; Rosanova, M.; Raz, A.; Tononi, G.; Massimini, M.; Laureys, S.; Boly, M.

10.1101/213504 — neuroscience — Posted on 2017-11-03

1511 Molecular identification of stone loaches of Choman River system, Tigris Basin, based on the Cytochrome b gene with an overview of the Cobitoidea Superfamily

Ghaderi, E.; Farahmand, H.; Bahrami Kamangar, B.; Nematollahi, M. A.

10.1101/210963 — molecular biology — Posted on 2017-11-03

1512 Initiation, elongation and realignment during influenza virus mRNA synthesis

te Velthuis, A.; Oymans, J.

10.1101/197210 — microbiology — Posted on 2017-11-03

1513 Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing

Shnayder, M.; Nachshon, A.; Krishna, B.; Poole, E.; Boshkov, A.; Binyamin, A.; Maza, I.; Sinclair, J.; Schwartz, M.; Stern-Ginossar, N.

10.1101/208603 — microbiology — Posted on 2017-11-03

1514 Enhanced JBrowse plugins for epigenomics data visualization

Hofmeister, B. T.; Schmitz, R. J.

10.1101/212654 — genomics — Posted on 2017-11-03

1515 Inferring adaptive gene-flow in recent African history

Busby, G.; Christ, R.; Band, G.; Leffler, E.; Si Le, Q.; Rockett, K.; Kwiatkowski, D.; Spencer, C.

10.1101/205252 — evolutionary biology — Posted on 2017-11-03

1516 Mitochondrial Methylation Two-Peak Profile Absent in Parkinson’s Disease Patient

Valente, A. X. C. N.; Liao, Q.; Rohkin, G.; Bouca-Machado, R.; Guedes, L. C.; Ferreira, J. J.; Lee, S. M.-Y.

10.1101/197731 — cell biology — Posted on 2017-11-03

1517 Interoperable and scalable metabolomics data analysis with microservices

10.1101/213603 — bioinformatics — Posted on 2017-11-03

1518 Distinct stimulatory mechanisms regulate the catalytic activity of Polycomb Repressive Complex 2 (PRC2)

Lee, C.-H.; Holder, M.; Grau, D.; Saldana-Meyer, R.; Ganai, R. A.; Zhang, J.; Wang, M.; Dobenecker, M.-W.; Reinberg, D.; Armache, K.-J.

10.1101/210542 — biochemistry — Posted on 2017-11-03

1519 Adapting machine-learning algorithms to design gene circuits

Hiscock, T. W.

10.1101/213587 — systems biology — Posted on 2017-11-03

1520 Endodermal differentiation is reconstructed by coordination of two parallel signaling systems derived from the stele in roots

Li, P.; Yu, Q.; Xu, C.; Gu, X.; Qi, S.; Wang, H.; Zhong, F.; Wu, S.

10.1101/210872 — plant biology — Posted on 2017-11-03

1521 Prediction Error and Repetition Suppression Have Distinct Effects on Neural Representations of Visual Information

Tang, M. F.; Smout, C. A.; Arabzadeh, E.; Mattingley, J. B.

10.1101/213710 — neuroscience — Posted on 2017-11-03

1522 The spent culture supernatant of Pseudomonas syringae contains azelaic acid

Javvadi, S. G.; Cescutti, P.; Rizzo, R.; Lonzarich, V.; Navarini, L.; Licastro, D.; Guarnaccia, C.; Venturi, V.

10.1101/213637 — microbiology — Posted on 2017-11-03

1523 Machine Learning of the Cardiac Phenome and Skin Transcriptome to Categorize Heart Disease in Systemic Sclerosis

Hinchcliff, M. E.; Frech, T. M.; Wood, T. A.; Huang, C.-C.; Lee, J.; Aren, K.; Ryan, J. J.; Wilson, B.; Beussink-Nelson, L.; Whitfield, M. L.; Deo, R. C.; Shah, S. J.

10.1101/213678 — genomics — Posted on 2017-11-03

1524 Molecular genetic diversity of donkey (Equus asinus) in South Korea

Yun, S.; Cho, G.

10.1101/213520 — genetics — Posted on 2017-11-03

1525 A multi-center study on factors influencing the reproducibility of in vitro drug-response studies

Niepel, M.; Hafner, M.; Williams, E. H.; Chung, M.; Barrette, A. M.; Stern, A. D.; Hu, B.; LINCS Consortium, ; Gray, J. W.; Birtwistle, M. R.; Heiser, L. M.; Sorger, P. K.

10.1101/213553 — cancer biology — Posted on 2017-11-03

1526 FireCloud, a scalable cloud-based platform for collaborative genome analysis: Strategies for reducing and controlling costs

Birger, C.; Hanna, M.; Salinas, E.; Neff, J.; Saksena, G.; Livitz, D.; Rosebrock, D.; Stewart, C.; Leshchiner, I.; Baumann, A.; Voet, D.; Cibulskis, K.; Banks, E.; Philippakis, A.; Getz, G.

10.1101/209494 — bioinformatics — Posted on 2017-11-03

1527 Cellular diversity of the somatosensory cortical map plasticity

Kole, K.; Scheenen, W.; Tiesinga, P.; Celikel, T.

10.1101/201293 — neuroscience — Posted on 2017-11-03

1528 Quantitative RNAseq Meta Analysis Of Alternative Exon Usage In C. elegans

Tourasse, N. J.; Millet, J. R. M.; Dupuy, D.

10.1101/134718 — genomics — Posted on 2017-11-03

1529 Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics

Sagner, A.; Gaber, Z.; Delile, J.; Kong, J. H.; Rousso, D. L.; Pearson, C. A.; Weicksel, S. E.; Melchionda, M.; Mousavy Gharavy, N.; Briscoe, J.; Novitch, B.

10.1101/104307 — developmental biology — Posted on 2017-11-03

1530 Smad9 is a key player of follicular selection in goose via keeping the balance of LHR transcription

Yu, D.; Chen, F.; Zhang, L.; Wang, H.; Chen, J.; Zhang, Z.; Li, J.; Xing, C.; Li, H.; Li, J.; Cai, Y.

10.1101/213546 — developmental biology — Posted on 2017-11-03

1531 Characterizing highly dynamic conformational states: the transcription bubble in RNAP-promoter open complex as an example

Lerner, E.; Ingargiola, A.; Weiss, S.

10.1101/188524 — biophysics — Posted on 2017-11-03

1532 Estimation of time-varying decision thresholds from the choice and reaction times with no assumption on the shape

Kang, Y. H. R.

10.1101/090217 — neuroscience — Posted on 2017-11-03

1533 RNA virus interference via CRISPR/Cas13a system in plants

Aman, R.; Ali, Z.; Butt, H.; Mahas, A.; Aljedaani, F.; Khan, M. Z.; Ding, S.; Mahfouz, M.

10.1101/213645 — molecular biology — Posted on 2017-11-03

1534 Genome-wide analysis yields new loci associating with aortic valve stenosis

Helgadottir, A.; Thorleifsson, G.; Gretarsdottir, S.; Stefansson, O. A.; Tragante, V.; Thorolfsdottir, R. B.; Jonsdottir, I.; Bjornsson, T.; Steinthorsdottir, V.; Verweij, N.; Nielsen, J. B.; Zhou, W.; Folkersen, L.; Martinsson, A.; Heydarpour, M.; Prakash, S.; Oskarsson, G.; Gudbjartsson, T.; Geirsson, A.; Olafsson, I.; Sigurdsson, E. L.; Almgren, P.; Melander, O.; Franco-Cereceda, A.; Hamsten, A.; Fritsche, L.; Lin, M.; Yang, B.; Hornsby, W.; Guo, D.; Brummett, C. M.; Abecasis, G.; Mathis, M.; Milewicz, D.; Body, S. C.; Eriksson, P.; Willer, C. J.; Hveem, K.; Newton-Cheh, C.; Smith, J. G.; D

10.1101/213595 — genetics — Posted on 2017-11-03

1535 Rev7 and 53BP1/Crb2 prevent RecQ helicase-dependent hyper-resection of DNA double-strand breaks

Leland, B. A.; Chen, A. B.; Zhao, A. Y.; Wharton, R. C.; King, M. C.

10.1101/213405 — genetics — Posted on 2017-11-03

1536 Effects Of Small-Scale Clustering Of Flowers On Pollinator Foraging Behaviour And Flower Visitation Rate

Akter, A.; Biella, P.; Klecka, J.

10.1101/126581 — ecology — Posted on 2017-11-03

1537 Degradation of cyclin B is critical for nuclear division in Trypanosoma brucei

Hayashi, H.; Akiyoshi, B.

10.1101/213652 — cell biology — Posted on 2017-11-03

1538 Molecular mechanism of the dual regulation of bacterial iron sulfur cluster biogenesis by CyaY and IscX

Pastore, A.; Adinolfi, S.; Puglisi, R.; Crack, J.; Iannuzzi, C.; Dal Piaz, F.; Konarev, P.; Svergun, D.; Martin, S.; Le Brun, N.

10.1101/212290 — biophysics — Posted on 2017-11-03

1539 Multi-state design of kinetically-controlled RNA aptamer ribosensors

Burke, C. R.; Sparkman-Yager, D.; Carothers, J. M.

10.1101/213538 — synthetic biology — Posted on 2017-11-03

1540 E/I balance enables adaptation to coordinate a neural population for a stable sensory representation

Gutierrez, G. J.; Deneve, S.

10.1101/211748 — neuroscience — Posted on 2017-11-03

1541 The ventral disc is a flexible microtubule organelle that depends on domed ultrastructure for functional attachment of Giardia lamblia

Dawson, S. C.; Nosala, C.

10.1101/213421 — microbiology — Posted on 2017-11-03

1542 Non-biological synthetic spike-in controls and the AMPtk software pipeline improve fungal high throughput amplicon sequencing data

Palmer, J. M.; Jusino, M. A.; Banik, M. T.; Lindner, D. L.

10.1101/213470 — bioinformatics — Posted on 2017-11-03

1543 High Peak Density Artifacts in Fourier Transform Mass Spectra and their Effects on Data Analysis

Mitchell, J. M.; Flight, R. M.; Wang, Q. J.; Kang, W.-Y.; Higashi, R. M.; Fan, T. W.- M.; Lane, A. N.; Moseley, H. N. B.

10.1101/191205 — systems biology — Posted on 2017-11-02

1544 Single-cell sequencing reveals αβ chain pairing shapes the T cell repertoire

Grigaityte, K.; Carter, J. A.; Goldfless, S. J.; Jeffery, E. W.; Hause, R. J.; Jiang, Y.; Koppstein, D.; Briggs, A. W.; Church, G. M.; Vigneault, F.; Atwal, G. S.

10.1101/213462 — immunology — Posted on 2017-11-02

1545 Genome-wide association study of delay discounting in 23,217 adult research participants of European ancestry

Sanchez-Roige, S.; Fontanillas, P.; Elson, S. L.; The 23andMe Research Team, ; Pandit, A.; Schmidt, E.; Forster, J.; Abecasis, G. R.; Gray, J. C.; de Wit, H.; Davis, L. K.; MacKillop, J.; Palmer, A. A.

10.1101/146936 — genetics — Posted on 2017-11-02

1546 Tradeoffs between microbial growth phases lead to frequency-dependent and non-transitive selection

Manhart, M.; Adkar, B. V.; Shakhnovich, E. I.

10.1101/096453 — evolutionary biology — Posted on 2017-11-02

1547 The Evolution Of Covert Signaling

Smaldino, P. E.; Flamson, T. J.; McElreath, R.

10.1101/132407 — evolutionary biology — Posted on 2017-11-02

1548 A Cell-Type-Specific Defect in Assembly of Influenza A Virus Particles in Primary Human Macrophages

Bedi, S.; Ono, A.

10.1101/213447 — microbiology — Posted on 2017-11-02

1549 Evidence that PV+ cells enhance temporal population codes but not stimulus-related timing in auditory cortex

Krause, B. M.; Murphy, C. A.; Uhlrich, D. J.; Banks, M. I.

10.1101/213249 — neuroscience — Posted on 2017-11-02

1550 Global State Changes Induce Non-reciprocal Reduction of Mutual Information in the Thalamocortical Network

Verner, R.; Banks, M. I.; Bartlett, E. L.

10.1101/213272 — neuroscience — Posted on 2017-11-02

1551 The C-terminal extension landscape of naturally presented HLA-I ligands

Guillaume, P.; Picaud, S.; Baumgaertner, P.; Montandon, N.; Schmidt, J.; Speiser, D. E.; Coukos, G.; Bassani-Sternberg, M.; Fillipakopoulos, P.; Gfeller, D.

10.1101/213264 — immunology — Posted on 2017-11-02

1552 Insights to the genetic etiology of a lifestyle-related disease with differential levels of severity using a hierarchy of common genetic variants

Fatakia, S. N.

10.1101/213124 — evolutionary biology — Posted on 2017-11-02

1553 Diversity, stability, and reproducibility in stochastically assembled microbial ecosystems

Goyal, A.; Maslov, S.

10.1101/213199 — ecology — Posted on 2017-11-02

1554 Bottom-up and top-down control of dispersal across major organismal groups: a coordinated distributed experiment

Fronhofer, E. A.; Legrand, D.; Altermatt, F.; Ansart, A.; Blanchet, S.; Bonte, D.; Chaine, A.; Dahirel, M.; De Laender, F.; De Raedt, J.; di Gesu, L.; Jacob, S.; Kaltz, O.; Laurent, E.; Little, C. J.; Madec, L.; Manzi, F.; Masier, S.; Pellerin, F.; Pennekamp, F.; Schtickzelle, N.; Therry, L.; Vong, A.; Winandy, L.; Cote, J.

10.1101/213256 — ecology — Posted on 2017-11-02

1555 The Improvement Of TSP Fertilizer Production & Quality

Chaouqi, N.; El Gharous, M.; Bouzziri, M.

10.1101/213223 — bioengineering — Posted on 2017-11-02

1556 Model reduction permits Turing instability analysis of arbitrary reaction-diffusion models

Smith, S.; Dalchau, N.

10.1101/213298 — synthetic biology — Posted on 2017-11-02

1557 Revisiting criteria for plant miRNA annotation in the era of big data

Axtell, M. J.; Meyers, B. C.

10.1101/213314 — plant biology — Posted on 2017-11-02

1558 Evidence that loss of consciousness under anesthesia is not associated with impaired stimulus representation in auditory cortex

Banks, M. I.; Krause, B. M.; Moran, N. S.; Grady, S. M.; Kakes, J.; Uhlrich, D. J.; Manning, K.

10.1101/213355 — neuroscience — Posted on 2017-11-02

1559 Associations between sexual habits, menstrual hygiene practices, demographics and the vaginal microbiome as revealed by Bayesian network analysis

Noyes, N.; Cho, K.-C.; Ravel, J.; Forney, L.; Abdo, Z.

10.1101/211631 — microbiology — Posted on 2017-11-02

1560 Application of the immunoregulatory receptor LILRB1 as a novel crystallisation chaperone for class I peptide-MHC complexes

Mohammed, F.; Stones, D.; Willcox, B. E.

10.1101/213207 — immunology — Posted on 2017-11-02

1561 De Novo Mutations Resolve Disease Transmission Pathways in Clonal Malaria

Redmond, S. N.; MacInnis, B. M.; Bopp, S.; Bei, A. K.; Ndiaye, D.; Hartl, D. L.; Wirth, D. F.; Volkman, S. K.; Neafsey, D. E.

10.1101/213397 — genomics — Posted on 2017-11-02

1562 Ultra-sensitive mutation detection and genome-wide DNA copy number reconstruction by error corrected circulating tumour DNA sequencing

Mansukhani, S.; Barber, L. J.; Moorcraft, S. Y.; Davidson, M.; Woolston, A.; Griffiths, B.; Fenwick, K.; Herman, B.; Matthews, N.; O'Leary, B.; Hulkki, S.; Gonzalez De Castro, D.; Hubank, M.; Patel, A.; Wotherspoon, A.; Okachi, A.; Rana, I.; Begum, R.; Davies, M.; Powles, T.; von Loga, K.; Turner, N.; Watkins, D.; Chau, I.; Cunningham, D.; Starling, N.; Gerlinger, M.

10.1101/213306 — genomics — Posted on 2017-11-02

1563 The phylogeography of westslope cutthroat trout

Young, M. K.; McKelvey, K. S.; Jennings, T.; Carter, K.; Cronn, R.; Keeley, E.; Loxterman, J.; Pilgrim, K.; Schwartz, M. K.

10.1101/213363 — evolutionary biology — Posted on 2017-11-02

1564 Effects of the veterinary anthelmintic moxidectin on dung beetle survival and ecosystem functioning

Manning, P.; Lewis, O. T.; Beynon, S. A.

10.1101/213173 — ecology — Posted on 2017-11-02

1565 Continuum Approximation of Invasion Probabilities

Borchering, R.; McKinley, S.

10.1101/213348 — ecology — Posted on 2017-11-02

1566 The Fission Yeast S-Phase Cyclin Cig2 Can Drive Mitosis

Magner, M.; Keifenheim, D.; Rhind, N.

10.1101/213330 — cell biology — Posted on 2017-11-02

1567 Modelling GxE with historical weather information improves genomic prediction in new environments

Gillberg, J.; Marttinen, P.; Mamitsuka, H.; Kaski, S.

10.1101/213231 — bioinformatics — Posted on 2017-11-02

1568 Determining the genetic basis of anthracycline-cardiotoxicity by molecular response QTL mapping in induced cardiomyocytes

Knowles, D. A.; Burrows, C. K.; Blischak, J. D.; Patterson, K. M.; Ober, C.; Pritchard, J. K.; Gilad, Y.

10.1101/212381 — genomics — Posted on 2017-11-02

1569 A versatile genetic tool for post-translational control of gene expression in Drosophila melanogaster

Sethi, S.; Wang, J. W.

10.1101/130120 — genetics — Posted on 2017-11-02

1570 A genetically encoded Ca2+ indicator based on circularly permutated sea anemone red fluorescent protein

Shen, Y.; Dana, H.; Abdelfattah, A. S.; Patel, R.; Shea, J.; Molina, R. S.; Rawal, B.; Rancic, V.; Chang, Y.-F.; Wu, L.; Chen, Y.; Qian, Y.; Wiens, M. D.; Hambleton, N.; Ballanyi, K.; Hughes, T. E.; Drobizhev, M.; Kim, D. S.; Koyama, M.; Schreiter, E. R.; Campbell, R. E.

10.1101/213082 — biophysics — Posted on 2017-11-02

1571 Transcranial real-time in vivo recording of electrophysiological neural activity in the rodent brain with near-infrared photoacoustic voltage-sensitive dye imaging

Kang, J.; Zhang, H. K.; Kadam, S. D.; Julie, F.; Valentine, H.; Kang, J. U.; Rahmim, A.; Gjedde, A.; Loew, L. M.; Wong, D. F.; Boctor, E. M.

10.1101/202408 — neuroscience — Posted on 2017-11-02

1572 A modified sequence capture approach allowing standard and methylation analyses of the same enriched genomic DNA sample

Olohan, L.; Gardiner, L.-J.; Lucaci, A.; Steuernagel, B.; Wulff, B.; Kenny, J.; Hall, N.; Hall, A.

10.1101/209585 — genomics — Posted on 2017-11-02

1573 A descriptive marker gene approach to single-cell pseudotime inference

Campbell, K. R.; Yau, C.

10.1101/060442 — bioinformatics — Posted on 2017-11-02

1574 ZINB-WaVE: A general and flexible method for signal extraction from single-cell RNA-seq data

Risso, D.; Perraudeau, F.; Gribkova, S.; Dudoit, S.; Vert, J.-P.

10.1101/125112 — bioinformatics — Posted on 2017-11-02

1575 The latent geometry of the human protein interaction network

Alanis-Lobato, G.; Mier, P.; Andrade-Navarro, M. A.

10.1101/213165 — systems biology — Posted on 2017-11-02

1576 Molecular identification of stone loaches of Choman River system, Tigris Basin, based on the Cytochrome b gene with an overview of the Cobitoidea Superfamily

Ghaderi, E.; Farahmand, H.; Bahrami Kamangar, B.; Nematollahi, M. A.

10.1101/210963 — molecular biology — Posted on 2017-11-02

1577 Bipolar filaments of human nonmuscle myosin 2-A and 2-B have distinct motile and mechanical properties

Melli, L.; Billington, N.; Sun, S. A.; Bird, J.; Nagy, A.; Friedman, T. B.; Takagi, Y.; Sellers, J. R.

10.1101/207514 — biophysics — Posted on 2017-11-02

1578 Chunking as a rational strategy for lossy data compression in visual working memory

Nassar, M. R.; Helmers, J. C.; Frank, M. J.

10.1101/098939 — neuroscience — Posted on 2017-11-02

1579 Population receptive field tuning properties of visual cortex during childhood

Dekker, T. M.; Schwarzkopf, D. S.; de Haas, B.; Nardini, M.; Sereno, M. I.

10.1101/213108 — neuroscience — Posted on 2017-11-02

1580 Testing the Efforts Model of Simultaneous Interpreting: An ERP Study

Koshkin, R.; Shtyrov, Y.; Ossadtchi, A.

10.1101/212951 — neuroscience — Posted on 2017-11-02

1581 Complementary metrics of human auditory nerve function derived from compound action potentials

Harris, K. C.; Vaden, K. I.; McClaskey, C. M.; Dias, J. W.; Dubno, J. R.

10.1101/213157 — neuroscience — Posted on 2017-11-02

1582 Comparison of feature representations in MRI-based MCI-to-AD conversion prediction

Gomez-Sancho, M.; Tohka, J.; Gomez-Verdejo, V.

10.1101/213132 — neuroscience — Posted on 2017-11-02

1583 Effects of partial selfing on the equilibrium genetic variance, mutation load and inbreeding depression under stabilizing selection

Abu Awad, D.; Roze, D.

10.1101/180000 — evolutionary biology — Posted on 2017-11-02

1584 The latent geometry of the human protein interaction network

Alanis-Lobato, G.; Andrade-Navarro, M. A.; Mier, P.

10.1101/213165 — systems biology — Posted on 2017-11-02

1585 Low affinity membrane transporters can increase net substrate uptake rate by reducing efflux

Bosdriesz, E.; Wortel, M. T.; Haanstra, J. R.; Wagner, M. J.; de la Torre Cortes, P.; Teusink, B.

10.1101/213140 — microbiology — Posted on 2017-11-02

1586 Modeling the temporal dynamics of the gut microbial community in adults and infants

Shenhav, L.; Furman, O.; Mizrahi, I.; Halperin, E.

10.1101/212993 — microbiology — Posted on 2017-11-02

1587 Determining the genetic basis of anthracycline-cardiotoxicity by molecular response QTL mapping in induced cardiomyocytes

Knowles, D. A.; Burrows, C. K.; Blischak, J. D.; Patterson, K. M.; Ober, C.; Pritchard, J. K.; Gilad, Y.

10.1101/212381 — genomics — Posted on 2017-11-02

1588 Two C++ Libraries for Counting Trees on a Phylogenetic Terrace

Biczok, R.; Bozsoky, P.; Eisenmann, P.; Ernst, J.; Ribizel, T.; Scholz, F.; Trefzer, A.; Weber, F.; Hamann, M.; Stamatakis, A.

10.1101/211276 — evolutionary biology — Posted on 2017-11-02

1589 Neurogenic decisions require a cell cycle independent function of the CD25B phosphatase

Bonnet, F.; Roussat, M.; Molina, A.; Azais, M.; Bel-Vialar, S.; Gautrais, J.; Pituello, F.; Agius, E.

10.1101/213074 — developmental biology — Posted on 2017-11-02

1590 A genetically encoded Ca2+ indicator based on circularly permutated sea anemone red fluorescent protein

10.1101/213082 — biophysics — Posted on 2017-11-02

1591 Interplay between folding and binding modulates protein sequences, structures, functions and regulation

Meszaros, B.; Dobson, L.; Ficho, E.; Tusnady, G. E.; Dosztanyi, Z.; Simon, I.

10.1101/211524 — bioinformatics — Posted on 2017-11-02

1592 A state representation for reinforcement learning and decision-making in the orbitofrontal cortex

Schuck, N. W.; Wilson, R. C.; Niv, Y.

10.1101/210591 — neuroscience — Posted on 2017-11-02

1593 Global Phylogenetic Analysis Of Escherichia coli And Plasmids Carrying The mcr-1 Gene Indicates Bacterial Diversity But Plasmid Restriction

Matamoros, S.; van Hattem, J. M.; Arcilla, M. S.; Willemse, N.; Melles, D.; Penders, J.; Nguyen Vinh, T.; Ngo Thi, H.; COMBAT consortium, ; de Jong, M. D.; Schultsz, C.

10.1101/136804 — microbiology — Posted on 2017-11-02

1594 A helicase-containing module defines a family of pCD630-like plasmids in Clostridium difficile

Smits, W. K.; Weese, J. S.; Roberts, A. P.; Harmanus, C.; Hornung, B.

10.1101/198473 — microbiology — Posted on 2017-11-02

1595 MaxTiC: Fast Ranking Of A Phylogenetic Tree By Maximum Time Consistency With Lateral Gene Transfers

Chauve, C.; Rafiey, A.; Davin, A. A.; Scornavacca, C.; Veber, P.; Boussau, B.; Szollosi, G.; Daubin, V.; Tannier, E.

10.1101/127548 — evolutionary biology — Posted on 2017-11-02

1596 The population genetics of spatial sorting

Phillips, B.; Perkins, A.

10.1101/210088 — evolutionary biology — Posted on 2017-11-02

1597 NOTCH-mediated non-cell autonomous regulation of chromatinstructure during senescence

Parry, A. J.; Hoare, M.; Bihary, D.; Hänsel-Hertsch, R.; Smith, S.; Tomimatsu, K.; Balasubramanian, S.; Kimura, H.; Samarajiwa, S.; Narita, M.

10.1101/212829 — cell biology — Posted on 2017-11-02

1598 The MYC antagonist MNT autoregulates its expression and supports proliferation in MAX deficient cells

Lafita-Navarro, M. C.; Liano-Pons, J.; Quintanilla, A.; Varela, I.; Ourique, F.; Bretones, G.; Blanco, R.; Aresti, J.; Carroll, P.; Hurlin, P.; Eisenman, R. N.; Delgado, M. D.; Leon, J.

10.1101/212944 — cancer biology — Posted on 2017-11-02

1599 Genome-Wide Mining, Characterization and Development of miRNA-SSRs in Arabidopsis thaliana

Kumar, A.; Chauhan, A.; Sharma, M.; Kompelli, S. K.; Gahlaut, V.; Ijaq, J.; Singh, K. P.; Gajula, M. N. V. P.; Suravajhala, P.; Balyan, H. S.; Gupta, P. K.

10.1101/203851 — bioinformatics — Posted on 2017-11-02

1600 Selective Recruitment of Cortical Neurons by Electrical Stimulation

Komarov, M.; Malerba, P.; Nunez, P.; Halgren, E.; Bazhenov, M.

10.1101/213017 — neuroscience — Posted on 2017-11-02

1601 Controlling for Intra-Subject and Inter-Subject Variability in Individual-Specific Cortical Network Parcellations

Kong, R.; Li, J.; Sun, N.; Sabuncu, M. R.; Schaefer, A.; Zuo, X.-N.; Holmes, A.; Eickhoff, S. B.; Yeo, B. T. T.

10.1101/213041 — neuroscience — Posted on 2017-11-02

1602 No kissing in the nucleus: Unbiased analysis reveals no evidence of trans chromosomal regulation of mammalian immune development

Johanson, T. M.; Coughlan, H. D.; Lun, A. T.; Bediaga, N. G.; Naselli, G.; Garnham, A. L.; Harrison, L. C.; Smyth, G. K.; Allan, R. S.

10.1101/212985 — genomics — Posted on 2017-11-02

1603 Evolutionary dynamics of mycorrhizal symbiosis in land plant diversification

Feijen, F. A. A.; Vos, R. A.; Nuytinck, J.; Merckx, V. S. F. T.

10.1101/213090 — evolutionary biology — Posted on 2017-11-02

1604 DNA methylation regulates transcriptional homeostasis of algal endosymbiosis in the coral model Aiptasia

Li, Y.; Liew, Y. J.; Cui, G.; Cziesielski, M. J.; Zahran, N.; Michell, C. T.; Voolstra, C. R.; Aranda Lastra, M.

10.1101/213066 — ecology — Posted on 2017-11-02

1605 The hummingbird and the hawk-moth:Species distribution, geographical partitioning, and macrocompetition across the United States

Halloway, A.; Whelan, C. J.; Brown, J. S.

10.1101/212894 — ecology — Posted on 2017-11-02

1606 An efficient gene regulatory network inference algorithm for early Drosophila melanogaster embryogenesis

Matsumoto, H.; Kiryu, H.; Kojima, Y.; Yaginuma, S.; Nikaido, I.

10.1101/213025 — bioinformatics — Posted on 2017-11-02

1607 Neuronal components of evaluating the human origin of abstract shapes

Goldberg, H.; Hart, Y.; Mayo, A.; Alon, U.; Malach, R.

10.1101/085902 — neuroscience — Posted on 2017-11-01

1608 Superior Colliculus Neuronal Ensemble Activity Signals Optimal Rather Than Subjective Confidence

Odegaard, B.; Grimaldi, P.; Cho, S. H.; Peters, M. A. K.; Lau, H.; Basso, M. A.

10.1101/157123 — neuroscience — Posted on 2017-11-01

1609 Cultivation and genomics of the first freshwater SAR11 (LD12) isolate

Henson, M. W.; Lanclos, V. C.; Faircloth, B. C.; Thrash, J. C.

10.1101/093567 — microbiology — Posted on 2017-11-01

1610 Potential clinical benefits of CBD-rich Cannabis extracts over purified CBD in treatment-resistant epilepsy: observational data meta-analysis

Pamplona, F. A.; Coan, A. C.

10.1101/212662 — pharmacology and toxicology — Posted on 2017-11-01

1611 Context of psychotropic drug delivery modulates its neurobehavioral effects: the case of methylphenidate

Sar-el, R.; Raz, G.; Lubianiker, N.; Sharon, H.; Hendler, T.

10.1101/212480 — neuroscience — Posted on 2017-11-01

1612 Evaluation of TRPM8 and TRPA1 participation in dental pulp sensitivity to cold stimulation

Michot, B.; Lee, C.; Gibbs, J. L.

10.1101/212688 — neuroscience — Posted on 2017-11-01

1613 Prefrontal control of visual distraction

Cosman, J.; Woodman, G.; Schall, J. D.

10.1101/212720 — neuroscience — Posted on 2017-11-01

1614 Development of real-time polymerase chain reaction assays allowing molecular detection of Echinococcus felidis, Echinococcus granulosus sensu stricto, and Echinococcus canadensis in carnivore feces samples, animal and human hydatid cyst material from Uganda and Kenya

Kopp, K. E. M.

10.1101/211920 — molecular biology — Posted on 2017-11-01

1615 Membrane curvature and the Tol-Pal complex determine polar localization of the chemoreceptor Tar in E. coli

Saaki, T.; Strahl, H.; Hamoen, L. W.

10.1101/212670 — microbiology — Posted on 2017-11-01

1616 Identification of Tumor-Reactive B Cells and Systemic IgG in Breast Cancer Based on Clonal Frequency in the Sentinel Lymph Node

McDaniel, J. R.; Pero, S. C.; Voss, W. N.; Shukla, G. S.; Sun, Y.; Schaetzle, S.; Lee, C.-H.; Horton, A. P.; Harlow, S.; Gollihar, J.; Ellefson, J. W.; Krag, C. C.; Tanno, Y.; Sidiropoulos, N.; Georgiou, G.; Ippolito, G. C.; Krag, D. N.

10.1101/212308 — immunology — Posted on 2017-11-01

1617 Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

Zhou, W.; Nielsen, J. B.; Fritsche, L. G.; Dey, R.; Elvestad, M. B.; Wolford, B. B.; LeFaive, J.; Lin, M.; Hveem, K.; Kang, H. M.; Abecasis, G. R.; Willer, C. J.; Lee, S.

10.1101/212357 — genomics — Posted on 2017-11-01

1618 Genomic Locus Modulating Corneal Thickness in the Mouse Identifies POU6F2 as a Potential Risk of Developing Glaucoma

King, R.; Struebing, F. L.; Li, Y.; Wang, J.; Koch, A. A.; Bailey, J. C.; Gharahkhan, P.; MacGregor, S.; Allingham, R. R.; Hauser, M. A.; Wiggs, J. L.; Geisert, E. E.

10.1101/212605 — genetics — Posted on 2017-11-01

1619 Genetic variation across the human olfactory receptor repertoire alters odor perception

Trimmer, C.; Keller, A.; Murphy, N. R.; Snyder, L. L.; Willer, J. R.; Nagai, M.; Katsanis, N.; Vosshall, L. B.; Matsunami, H.; Mainland, J. D.

10.1101/212431 — genetics — Posted on 2017-11-01

1620 Ancestral Reconstruction of Gene Blocks using an Event-Based Method

Nguyen, H. N.; Jain, A.; Eulenstein, O.; Friedberg, I.

10.1101/212886 — evolutionary biology — Posted on 2017-11-01

1621 Duplication and divergence of Sox genes in spiders

Paese, C. L. B.; Leite, D. J.; Schoenauer, A.; McGregor, A. P.; Russell, S.

10.1101/212647 — evolutionary biology — Posted on 2017-11-01

1622 Head-Direction drift in rat pups is consistent with an angular path-integration process

Derdikman, D.; Tocker, G.; Borodach, E.; Bjerknes, T. L.; Moser, M.-B.; Moser, E. I.

10.1101/212852 — bioinformatics — Posted on 2017-11-01

1623 Voltage-dependent inward currents in smooth muscle cells of skeletal muscle arterioles

Ulyanova, A. V.; Shirokov, R. E.

10.1101/211540 — physiology — Posted on 2017-11-01

1624 Species and Cell-Type Properties of Classically Defined Human and Rodent Neurons and Glia

Xu, X.; Stoyanova, E.; Lemiesz, A.; Xing, J.; Mash, D. C.; Heintz, N.

10.1101/212696 — neuroscience — Posted on 2017-11-01

1625 An automated statistical technique for counting distinct multiple sclerosis lesions can recover aspects of lesion history and provide relevant disease information

Dworkin, J. D.; Linn, K. A.; Oguz, I.; Fleishman, G. M.; Bakshi, R.; Nair, G.; Calabresi, P. A.; Henry, R. G.; Oh, J.; Papinutto, N.; Pelletier, D.; Rooney, W.; Stern, W.; Sicotte, N. L.; Reich, D. S.; Shinohara, R. T.

10.1101/212860 — neuroscience — Posted on 2017-11-01

1626 Morphological constraints on cerebellar granule cell combinatorial diversity

Gilmer, J. I.; Person, A. L.

10.1101/212324 — neuroscience — Posted on 2017-11-01

1627 Post-catalytic spliceosome structure reveals mechanism of 3'-splice site selection

Wilkinson, M. E.; Fica, S. M.; Galej, W. P.; Norman, C. M.; Newman, A. J.; NAGAI, K.

10.1101/212811 — molecular biology — Posted on 2017-11-01

1628 Gene network analysis identifies a central post-transcriptional regulator of cellular stress survival

Tien, M. Z.; Fiebig, A.; Crosson, S.

10.1101/212902 — microbiology — Posted on 2017-11-01

1629 Cross-Site Comparison of Ribosomal Depletion Kits for Illumina RNAseq Library Construction

10.1101/212639 — genomics — Posted on 2017-11-01

1630 Genomic Loci Modulating Retinal Ganglion Cell Death Following Elevated IOP in the Mouse

Struebing, F. L.; King, R.; Li, Y.; Bailey, J. C.; NEIGHBORHOOD Consortium, ; Wiggs, J.; Geisert, E. E.

10.1101/212753 — genetics — Posted on 2017-11-01

1631 Nearly Neutral Evolution Across the Drosophila melanogaster Genome

Castellano, D.; James, J.; Eyre-Walker, A.

10.1101/212779 — evolutionary biology — Posted on 2017-11-01

1632 The fluid membrane determines mechanics of red blood cell extracellular vesicles and is softened in hereditary spherocytosis

Vorselen, D.; van Dommelen, S.; Sorkin, R.; Schiller, J.; van Wijk, R.; Schiffelers, R.; Wuite, G.; Roos, W.

10.1101/212456 — biophysics — Posted on 2017-11-01

1633 The molecular basis for Pompe disease revealed by the structure of human acid α-glucosidase

Deming, D.; Lee, K.; McSherry, T.; Wei, R. R.; Edmunds, T.; Garman, S. C.

10.1101/212837 — biochemistry — Posted on 2017-11-01

1634 Cadmium exposure inhibits branching morphogenesis and causes alterations consistent with HIF-1α inhibition in human primary breast organoids

Rocco, S. A.; Koneva, L.; Middleton, L. Y. M.; Thong, T.; Solanki, S.; Karram, S.; Nambunmee, K.; Harris, C.; Rozek, L. S.; Sartor, M. A.; Shah, Y. M.; Colacino, J.

10.1101/208157 — pharmacology and toxicology — Posted on 2017-11-01

1635 Rapid high-resolution measurement of DNA replication timing by droplet digital PCR

Batrakou, D. G.; Heron, E. D.; Nieduszynski, C. A.

10.1101/208546 — molecular biology — Posted on 2017-11-01

1636 Conserved patterns of somatic mutations in human peripheral blood cells

Liggett, L. A.; Sharma, A.; De, S.; DeGregori, J.

10.1101/208066 — genetics — Posted on 2017-11-01

1637 Parallel paleogenomic transects reveal complex genetic history of early European farmers

Lipson, M.; Szecsenyi-Nagy, A.; Mallick, S.; Posa, A.; Stegmar, B.; Keerl, V.; Rohland, N.; Stewardson, K.; Ferry, M.; Michel, M.; Oppenheimer, J.; Broomandkhoshbacht, N.; Harney, E.; Nordenfelt, S.; Llamas, B.; Mende, B. G.; Köhler, K.; Oross, K.; Bondar, M.; Marton, T.; Osztas, A.; Jakucs, J.; Paluch, T.; Horvath, F.; Csengeri, P.; Koos, J.; Sebok, K.; Anders, A.; Raczky, P.; Regenye, J.; Barna, J. P.; Fabian, S.; Serlegi, G.; Toldi, Z.; Nagy, E. G.; Dani, J.; Molnar, E.; Palfi, G.; Mark, L.; Melegh, B.; Banfai, Z.; Domboroczki, L.; Fernandez-Eraso, J.; Mujika-Alustiza, J. A.; Alonso

10.1101/114488 — genetics — Posted on 2017-11-01

1638 The Transcriptional Logic of Mammalian Neuronal Diversity

Sugino, K.; Clark, E.; Schulmann, A.; Shima, Y.; Wang, L.; Hunt, D. L.; Hooks, B. M.; Trankner, D.; Chandrashekar, J.; Picard, S.; Lemire, A.; Spruston, N.; Hantman, A.; Nelson, S. B.

10.1101/208355 — evolutionary biology — Posted on 2017-11-01

1639 Active deep learning reduces annotation burden in automatic cell segmentation

Chowdhury, A.; Biswas, S.; Bianco, S.

10.1101/211060 — bioinformatics — Posted on 2017-11-01

1640 Methods for addressing the protein-protein interaction between histone deacetylase 6 and ubiquitin

dos Santos Passos, C.; Deschamps, N.; Choi, Y.; Cohen, R. E.; Perozzo, R.; Nurisso, A.; Simoes-Pires, C.

10.1101/203372 — biochemistry — Posted on 2017-11-01

1641 Predicting drug safety and communicating risk: benefits of a Bayesian approach

Lazic, S. E.; Edmunds, N.; Pollard, C. E.

10.1101/193169 — pharmacology and toxicology — Posted on 2017-11-01

1642 Distributed Rhythm Generators Underlie Caenorhabditis elegans Forward Locomotion

Fouad, A. D.; Teng, S.; Mark, J. R.; Liu, A.; Alvarez-Illera, P.; Ji, H.; Du, A.; Bhirgoo, P.; Cornblath, E.; Guan, A.; Zhen, M.; Fang-Yen, C.

10.1101/141911 — neuroscience — Posted on 2017-11-01

1643 Near-Atomic Cryo-EM Imaging of a Small Protein Displayed on a Designed Scaffolding System

Liu, Y.; Gonen, S.; Gonen, T.; Yeates, T.

10.1101/212233 — molecular biology — Posted on 2017-11-01

1644 Impaired competence in flagellar mutants of Bacillus subtilis is connected to the regulatory network governed by DegU

Hoelscher, T.; Schiklang, T.; Dragos, A.; Dietel, A.-K.; Kost, C.; Kovacs, A. T.

10.1101/194027 — microbiology — Posted on 2017-11-01

1645 Junction-based lamellipodia drive endothelial cell rearrangements in vivo via a VE-cadherin/F-actin based oscillatory ratchet mechanism

Paatero, I.; Sauteur, L.; Lee, M.; Lagendijk, A. K.; Heutschi, D.; Bieli, D.; Hogan, B. M.; Affolter, M.; Belting, H.-G.

10.1101/212522 — developmental biology — Posted on 2017-11-01

1646 Stratification of TAD boundaries identified in reproducible Hi-C contact matrices reveals preferential insulation of super-enhancers by strong boundaries

Gong, Y.; Lazaris, C.; Sakellaropoulos, T.; Lozano, A.; Kambadur, P.; Ntziachristos, P.; Aifantis, I.; Tsirigos, A.

10.1101/141481 — bioinformatics — Posted on 2017-11-01

1647 Ontology-based similarity calculations with an improved annotation model

Koehler, S.

10.1101/199554 — bioinformatics — Posted on 2017-11-01

1648 A Noninvasive Molecular Clock for Fetal Development Predicts Gestational Age and Preterm Delivery

Ngo, T. T.; Moufarrej, M. N.; Rasmussen, M.-L. H.; Camunas-Soler, J.; Pan, W.; Okamoto, J.; Neff, N.; Liu, K.; Wong, R. J.; Downes, K.; Tibshirani, R.; Shaw, G. M.; Skotte, L.; Stevenson, D. K.; Biggio, J. R.; Elovitz, M. A.; Melbye, M.; Quake, S. R.

10.1101/212910 — bioengineering — Posted on 2017-11-01

1649 Proteome-wide analysis of phospho-regulated PDZ domain interactions through phosphomimetic proteomic peptide phage display

Sundell, G. N.; Arnold, R.; Ali, M.; Orts, J.; Guentert, P.; Chi, C. N.; Ivarsson, Y.

10.1101/211250 — biochemistry — Posted on 2017-11-01

1650 Abnormal Speech Motor Control in Individuals with 16p11.2 Deletions

Demopoulos, C.; Kothare, H.; Mizuiri, D.; Henderson-Sabes, J.; Fregeau, B.; Tjernagel, J.; Houde, J.; Sherr, E.; Nagarajan, S. S.

10.1101/165316 — neuroscience — Posted on 2017-11-01

1651 Expanding the Atlas of Functional Missense Variation for Human Genes

Weile, J.; Sun, S.; Cote, A. G.; Knapp, J.; Verby, M.; Mellor, J. C.; Wu, Y.; Pons, C.; Wong, C.; van Lieshout, N.; Yang, F.; Tasan, M.; Tan, G.; Yang, S.; Fowler, D. M.; Nussbaum, R.; Bloom, J. D.; Vidal, M.; Hill, D. E.; Aloy, P.; Roth, F. P.

10.1101/166595 — molecular biology — Posted on 2017-11-01

1652 Mechanistic Implications of Enhanced Editing by a HyperTRIBE RNA-binding protein

Xu, W.; Rahman, R.; Rosbash, M.

10.1101/156828 — molecular biology — Posted on 2017-11-01

1653 Germline determinants of the somatic mutation landscape in 2,642 cancer genomes

Waszak, S. M.; Tiao, G.; Zhu, B.; Rausch, T.; Muyas, F.; Rodriguez-Martin, B.; Rabionet, R.; Yakneen, S.; Escaramis, G.; Li, Y.; Saini, N.; Roberts, S. A.; Demidov, G. M.; Pitkanen, E.; Delaneau, O.; Heredia-Genestar, J. M.; Weischenfeldt, J.; Shringarpure, S. S.; Chen, J.; Nakagawa, H.; Alexandrov, L. B.; Drechsel, O.; Dursi, L. J.; Segre, A. V.; Garrison, E.; Erkek, S.; Habermann, N.; Urban, L.; Khurana, E.; Cafferkey, A.; Hayashi, S.; Imoto, S.; Aaltonen, L. A.; Alvarez, E. G.; Baez-Ortega, A.; Bailey, M.; Bosio, M.; Bruzos, A. L.; Buchhalter, I.; Bustamante, C. D.; Calabrese, C.; DiBiase,

10.1101/208330 — genomics — Posted on 2017-11-01

1654 Enhanced JBrowse plugins for epigenomics data visualization

Hofmeister, B. T.; Schmitz, R. J.

10.1101/212654 — genomics — Posted on 2017-11-01

1655 The amount of nitrogen used for photosynthesis governs molecular evolution in plants

Kelly, S.

10.1101/162693 — evolutionary biology — Posted on 2017-11-01

1656 Social fluidity mobilizes contagion in human and animal populations

Colman, E.; Colizza, V.; Hanks, E. M.; Modlmeier, A. P.; Hughes, D. P.; Bansal, S.

10.1101/170266 — ecology — Posted on 2017-11-01

1657 Widespread dynamic and pleiotropic expression of the melanocortin-1-receptor (MC1R) system is conserved across chick, mouse and human embryonic development

Thomas, A.; Heux, P.; Santos, C.; Arulvasan, W.; Solanky, N.; Carey, M. E.; Gerrelli, D.; Kinsler, V. A.; Etchevers, H. C.

10.1101/212712 — developmental biology — Posted on 2017-11-01

1658 Coordination between discrete Mitotic Arrest Deficient 1 (MAD1) domains is required for efficient mitotic checkpoint signaling

Ji, W.; Luo, Y.; Ahmad, E.; Liu, S.-T.

10.1101/212704 — cell biology — Posted on 2017-11-01

1659 Variation in traction forces during cell cycle progression

Vianay, B.; Senger, F.; Alamos, S.; Anjur-Dietrich, M.; Bearce, E.; Cheeseman, B.; Lee, L.; Thery, M.

10.1101/212472 — cell biology — Posted on 2017-11-01

1660 FGIN-1-27, an agonist at translocator protein 18 kDa (TSPO), has anti-anxiety and anti-panic effects in non-mammalian models

Cueto-Escobedo, J.; Rodriguez-Landa, J. F.; Maximino, C.

10.1101/056507 — pharmacology and toxicology — Posted on 2017-11-01

1661 Training and spontaneous reinforcement of neuronal assemblies by spike timing plasticity

Ocker, G. K.; Doiron, B.

10.1101/066969 — neuroscience — Posted on 2017-11-01

1662 Selection-driven cost-efficiency optimisation of transcripts modulates gene evolutionary rate in bacteria

Seward, E. A.; Kelly, S.

10.1101/136861 — evolutionary biology — Posted on 2017-11-01

1663 Compositional Mediation Analysis for Microbiome Studies

Sohn, M. B.; Li, H.

10.1101/149419 — bioinformatics — Posted on 2017-11-01

1664 Neural mechanisms of speed-accuracy tradeoff of visual search: Saccade vigor, targeting errors, superior colliculus and frontal eye field

Reppert, T.; Servant, M.; Heitz, R.; Schall, J. D.

10.1101/212621 — neuroscience — Posted on 2017-11-01

1665 Equality between the sexes in plants for costs of reproduction; evidence from the dioecious Cape genus Leucadendron (Proteaceae)

Midgley, J. J.; West, A.; Cramer, M.

10.1101/212555 — evolutionary biology — Posted on 2017-11-01

1666 Functional Connectomics from Data: Probabilistic Graphical Models for Neuronal Network of C. elegans

Liu, H.; Kim, J.; Shlizerman, E.

10.1101/212423 — bioinformatics — Posted on 2017-11-01

1667 Avian thermoregulation in the heat: phylogenetic variation among avian orders in evaporative cooling capacity and heat tolerance

Smit, B.; Whitfield, M. C.; Talbot, W. A.; Gerson, A. R.; McKechnie, A. E.; Wolf, B. O.

10.1101/211730 — zoology — Posted on 2017-11-01

1668 Scalable Bayesian inference for high-dimensional neural receptive fields

Aoi, M.; Pillow, J. W.

10.1101/212217 — neuroscience — Posted on 2017-11-01

1669 Finding domain-general metacognitive mechanisms requires using appropriate tasks

Ruby, E.; Giles, N.; Lau, H.

10.1101/211805 — neuroscience — Posted on 2017-11-01

1670 A simulation and comparison of dynamic functional connectivity methods

Thompson, W. H.; Richter, C. G.; Plaven-Sigray, P.; Fransson, P.

10.1101/212241 — neuroscience — Posted on 2017-11-01

1671 Prediction of Epileptic Seizures based on Mean Phase Coherence

Aggarwal, G.; Gandhi, T. K.

10.1101/212563 — neuroscience — Posted on 2017-11-01

1672 Functional categories in macaque frontal eye field

Lowe, K.; Schall, J. D.

10.1101/212589 — neuroscience — Posted on 2017-11-01

1673 Impact of sequence variant detection and bacterial DNA extraction methods on the measurement of microbial community composition in human stool

Hughes, R.; Alkan, Z.; Keim, N.; Kable, M.

10.1101/212134 — molecular biology — Posted on 2017-11-01

1674 Determining the genetic basis of anthracycline-cardiotoxicity by molecular response QTL mapping in induced cardiomyocytes

Knowles, D. A.; Burrows, C. K.; Blischak, J. D.; Patterson, K. M.; Ober, C.; Pritchard, J. K.; Gilad, Y.

10.1101/212381 — genomics — Posted on 2017-11-01

1675 OMGene: Mutual improvement of gene models through optimisation of evolutionary conservation

Dunne, M.; Kelly, S.

10.1101/212530 — genomics — Posted on 2017-11-01

1676 Inferring the evolutionary reduction of corm lobation in Isoëtes using Bayesian model-averaged ancestral state reconstruction

Freund, F.; Freyman, W.; Rothfels, C.

10.1101/212316 — evolutionary biology — Posted on 2017-11-01

1677 Within-infection diversity of Plasmodium falciparum antigens reflects host-mediated selection

Early, A. M.; Lievens, M.; MacInnis, B.; Ockenhouse, C. F.; Volkman, S. K.; RTS,S Clinical Trial Partnership Committee of Inve, ; Wirth, D. F.; Neafsey, D. E.

10.1101/212209 — evolutionary biology — Posted on 2017-11-01

1678 A note on measuring natural selection on principal component scores

Chong, V. K.; Fung, H. F.; Stinchcombe, J. R.

10.1101/212258 — evolutionary biology — Posted on 2017-11-01

1679 Natural selection interacts with the local recombination rate to shape the evolution of hybrid genomes

Schumer, M.; Xu, C.; Powell, D.; Durvasula, A.; Skov, L.; Holland, C.; Sankararaman, S.; Andolfatto, P.; Rosenthal, G.; Przeworski, M.

10.1101/212407 — evolutionary biology — Posted on 2017-11-01

1680 The effect of offspring number on the adaptation speed of a polygenic trait

Pfenninger, M.

10.1101/212613 — evolutionary biology — Posted on 2017-11-01

1681 REMAP: An online remote sensing application for land cover classification and monitoring

Murray, N. J.; Keith, D. A.; Simpson, D.; Wilshire, J. H.; Lucas, R. M.

10.1101/212464 — ecology — Posted on 2017-11-01

1682 Subsoil arbuscular mycorrhizal fungal communities in arable soil differ from those in topsoil

Sosa-Hernandez, M. A.; Roy, J.; Hempel, S.; Kautz, T.; Koepke, U.; Uksa, M.; Schloter, M.; Caruso, T.; Rillig, M. C.

10.1101/212597 — ecology — Posted on 2017-11-01

1683 Early Subset Of Cerebellar Nuclei Neurons Derived From Mesencephalon In Mice

Rahimi-Balaei, M.; Jiao, X.; Parkinson, F.; Yeganeh, B.; Marzban, H.

10.1101/212571 — developmental biology — Posted on 2017-11-01

1684 Perturbed Mitochondrial Metabolism in Islets from Donors with Type-2 Diabetes

Sun, J.; Jain, R.; Andersson, L. E.; Medina, A.; Storm, P.; Spegel, P.; Mulder, H.

10.1101/212548 — cell biology — Posted on 2017-11-01

1685 Germline loss of MBD4 predisposes to leukaemia due to a mutagenic cascade driven by 5mC

Sanders, M. A.; Chew, E.; Flensburg, C.; Zeilemaker, A.; Miller, S. E.; al Hinai, A.; Bajel, A.; Luiken, B.; Rijken, M.; Mclennan, T.; Hoogenboezem, R. M.; Kavelaars, F. G.; Blewitt, M. E.; Bindels, E. M.; Alexander, W. S.; Löwenberg, B.; Roberts, A. W.; Valk, P. J. M.; Majewski, I.

10.1101/180588 — cancer biology — Posted on 2017-11-01

1686 Clingen Cancer Somatic Working Group: standardizing and democratizing access to cancer molecular diagnostic data to drive translational research

Madhavan, S.; Ritter, D.; Micheel, C.; Rao, S.; Roy, A.; Sonkin, D.; McCoy, M.; Griffith, M.; Griffith, O. L.; McGarvey, P.; Kulkarni, S.; The Clingen Somatic Working Group,

10.1101/212225 — bioinformatics — Posted on 2017-11-01

1687 MetaCompass: Reference-guided Assembly of Metagenomes

Cepeda, V.; Liu, B.; Almeida, M.; Hill, C. M.; Koren, S.; Treangen, T. J.; Pop, M.

10.1101/212506 — bioinformatics — Posted on 2017-11-01

1688 Evaluation of protein-ligand docking methods on peptide-ligand complexes for docking small ligands to peptides

Singh, S.; Srivastava, H. K.; Kishor, G.; Singh, H.; Agrawal, P.; Raghava, G. P. S.

10.1101/212514 — bioinformatics — Posted on 2017-11-01

1689 Detection of cytosolic Shigella flexneri via a C-terminal triple-arginine motif of GBP1 inhibits actin-based motility

Piro, A.; Hernandez, D.; Luoma, S.; Feeley, E.; Finethy, R.; Yirga, A.; Frickel, E.; Lesser, C.; Coers, J.

10.1101/212175 — microbiology — Posted on 2017-11-01

1690 Effects of mutating α-tubulin lysine 40 on sensory dendrite development

Jenkins, B.; Saunders, H. A. J.; Record, H. L.; Johnson-Schlitz, D. M.; Wildonger, J.

10.1101/212373 — cell biology — Posted on 2017-11-01

1691 Histone Deacetylase 11 is an ε-N-Myristoyllysine Hydrolase

Moreno-Yruela, C.; Galleano, I.; Madsen, A. S.; Olsen, C. A.

10.1101/211839 — biochemistry — Posted on 2017-11-01

1692 An essential post-developmental role for Lis1 in mice

Hines, T. J.; Gao, X.; Sahu, S.; Lange, M. M.; Turner, J. R.; Twiss, J. L.; Smith, D. S.

10.1101/212340 — neuroscience — Posted on 2017-11-01

1693 Axons from the trigeminal ganglia are the earliest afferent projections to the mouse cerebellum

Marzban, H.; Rahimi Balaei, M.; Hawkes, R.

10.1101/212076 — neuroscience — Posted on 2017-11-01

1694 Intermittent Ca2+ signals mediated by Orai1 regulate basal T cell motility

Dong, T. X.; Othy, S.; Greenberg, M. L.; Jairaman, A.; Akunwafo, C.; Leverrier, S.; Yu, Y.; Parker, I.; Dynes, J. L.; Cahalan, M. D.

10.1101/212274 — immunology — Posted on 2017-11-01

1695 Size-reduced embryos reveal a gradient scaling based mechanism for zebrafish somite formation

Ishimatsu, K.; Hiscock, T. W.; Collins, Z. M.; Sari, D. W. K.; Lischer, K.; Richmond, D. L.; Bessho, Y.; Matsui, T.; Megason, S. G.

10.1101/211615 — developmental biology — Posted on 2017-11-01

1696 Processive movement of actin by biased polymerization: a new paradigm of axonal transport

Chakrabarty, N.; Dubey, P.; Tang, Y.; Ganguly, A.; Ladt, K.; Leterrier, C.; Jung, P.; Roy, S.

10.1101/212449 — neuroscience — Posted on 2017-11-01

Archive, 2017-11