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Archive, 2020-09

3 Biological invasions alter environmental microbiomes: a meta-analysis
Malacrino, A.; Sadowski, V. A.; Martin, T. K.; Cavichiolli de Oliveira, N.; Brackett, I. J.; Feller, J. D.; Harris, K. J.; Combita Heredia, O.; Vescio, R.; Bennett, A. E.
10.1101/2020.06.17.157883 — ecology — Posted on 2020-09-30
5 Functional Landscape of SARS-CoV-2 Cellular Restriction
Martin-Sancho, L.; Lewinski, M. K.; Pache, L.; Stoneham, C.; YIN, X.; Pratt, D.; Churas, C.; Rosenthal, S. B.; Liu, S.; De Jesus, P. D.; O'Neill, A. M.; Gounder, A. P.; Nguyen, C.; Pu, Y.; Oom, A. L.; Miorin, L.; Rodriguez-Frandsen, A.; Urbanowski, M.; Shaw, M. L.; Chang, M. W.; Benner, C.; Frieman, M.; Garcia-Sastre, A.; Ideker, T.; Hultquist, J. F.; Guatelli, J.; Chanda, S.
10.1101/2020.09.29.319566 — microbiology — Posted on 2020-09-30
7 Use of non-invasive intracranial pressure pulse waveform to monitor patients with End-Stage Renal Disease (ESRD)
Rickli, C.; Cosmoski, L. D.; dos Santos, F. A.; Frigieri, G. H.; Rabelo, N. N.; Schuinski, A. M.; Mascarenhas, S.; Vellosa, J. C. R.
10.1101/2020.09.30.320085 — neuroscience — Posted on 2020-09-30
12 Disturbance Triggers Non-Linear Microbe-Environment Feedbacks
Sengupta, A.; Fansler, S. J.; Chu, R. K.; Danczak, R. E.; Garayburu-Caruso, V. E.; Renteria, L.; Song, H.-S.; Toyoda, J.; Wells, J.; Stegen, J. C.
10.1101/2020.09.30.314328 — ecology — Posted on 2020-09-30
16 Early-life feeding accelerates gut microbiome maturation in piglets
Choudhury, R.; Middelkoop, A.; Gerrits, W. J. J.; Kemp, B.; Bolhuis, L.; Kleerebezem, M.
10.1101/2020.09.30.320275 — microbiology — Posted on 2020-09-30
19 Chromoplast differentiation in bell pepper (Capsicum annuum) fruits
Roediger, A.; Agne, B.; Dobritzsch, D.; Helm, S.; Mueller, F.; Poetzsch, N.; Baginsky, S.
10.1101/2020.09.29.299313 — plant biology — Posted on 2020-09-30
21 A Statistical Pipeline for Identifying Physical Features that Differentiate Classes of 3D Shapes
Wang, B.; Sudijono, T.; Kirveslahti, H.; Gao, T.; Boyer, D. M.; Mukherjee, S.; Crawford, L.
10.1101/701391 — bioinformatics — Posted on 2020-09-30
24 Histone modifications during the life cycle of the brown alga Ectocarpus
Bourdareau, S.; Tirichine, L.; Lombard, B.; Damarys, L.; Scornet, D.; Wu, Y.; Coelho, S. M.; Cock, J. M.
10.1101/2020.03.09.980763 — genomics — Posted on 2020-09-30
25 A pseudomolecule assembly of the Rocky Mountain elk genome reveals putative immune system gene loss near chromosomal fissions
Masonbrink, R.; Alt, D.; Bayles, D. O.; Boggiatto, P.; Edwards, W.; Tatum, F.; Williams, J.; Wilson-Welder, J.; Zimin, A.; Severin, A.; Olsen, S.
10.1101/2020.09.30.320150 — genomics — Posted on 2020-09-30
26 Hmx3a has essential functions in zebrafish spinal cord, ear and lateral line development.
England, S. J.; Cerda, G. A.; Kowalchuk, A. M.; Sorice, T.; Grieb, G. M.; Lewis, K. E.
10.1101/2020.01.23.917468 — genetics — Posted on 2020-09-30
28 Allele-specific antisense oligonucleotide therapy for dominantly inherited hearing impairment DFNA9.
de Vrieze, E.; Peijenborg, J.; Canas Martin, J.; Martens, A.; van der Heuvel, S.; Neveling, K.; Pennings, R.; Kremer, H.; van Wijk, E.
10.1101/2020.09.29.316364 — genetics — Posted on 2020-09-30
29 Positive selection inhibits plasmid coexistence in bacterial genomes
Carrilero, L.; Kottara, A.; Guymer, D.; Harrison, E.; Hall, J.; Brockhurst, M.
10.1101/2020.09.29.318741 — evolutionary biology — Posted on 2020-09-30
32 A role for circular code properties in translation
Giannerini, S.; Danielli, A.; Gonzalez, D. L.; Goracci, G.
10.1101/2020.09.28.317016 — molecular biology — Posted on 2020-09-30
34 Spatially resolved transcriptome profiles of mammalian kidneys illustrate the molecular complexity of functional nephron segments, cell-to-cell interactions and genetic variants.
Raghubar, A. M.; Pham, D. T.; Tan, X.; Grice, L. F.; Crawford, J.; Lam, P. Y.; Andersen, S. B.; Yoon, S.; Ng, M. S. Y.; Teoh, S. M.; Holland, S. E.; Stewart, A.; Francis, L.; Combes, A. N.; Kassianos, A. J.; Healy, H.; Nguyen, Q.; Mallett, A. J.
10.1101/2020.09.29.317917 — molecular biology — Posted on 2020-09-30
35 A cross-species interaction with a symbiotic commensal enables cell-density-dependent growth and in vivo virulence of an oral pathogen
Hoare, A.; Wang, H.; Meethil, A.; Abusleme, L.; Hong, B.-Y.; Moutsopoulos, N.; Marsh, P. D.; Hajishengallis, G.; Diaz, P. I.
10.1101/2020.09.30.320770 — microbiology — Posted on 2020-09-30
37 Constitutive androstane receptor directs T cell adaptation to bile acids in the small intestine
Chen, M. L.; Huang, X.; Wang, H.; Liu, Y.; Shang, J.; Eliason, A.; Hegner, C.; Park, H.; Frey, B.; Wang, G.; Kojetin, D. J.; Weaver, C. T.; Pipkin, M. E.; Moore, D. D.; Sundrud, M. S.
10.1101/2020.07.30.229864 — immunology — Posted on 2020-09-30
39 White matter neuroanatomical predictors of aphasic verb retrieval
Dresang, H. C.; Hula, W. D.; Yeh, F.-C.; Warren, T.; Dickey, M. W.
10.1101/2020.09.30.316844 — neuroscience — Posted on 2020-09-30
40 Harmonicity aids hearing in noise
McPherson, M. J.; Grace, R. C.; McDermott, J. H.
10.1101/2020.09.30.321000 — neuroscience — Posted on 2020-09-30
41 An Empirical Comparison of Preservation Methodsfor Synthetic DNA Data Storage
Organick, L. W.; Nguyen, B. H.; McAmis, R.; Chen, W. D.; Kohll, A. X.; Dumas Ang, S.; Grass, R. N.; Ceze, L. H.; Strauss, K.
10.1101/2020.09.19.304014 — synthetic biology — Posted on 2020-09-30
42 Protein arginine methyltransferase 5 promotes metastasis via enhancing EGFR transcription and modulating AKT1 activation by methylation
Huang, L.; Zhang, X.-O.; Verdejo-Torres, O.; Wigglesworth, K.; Sun, X.; Sallis, B.; Moon, D.; Huang, T.; Rozen, E.; Zhang, L.; Wang, G.; Shohet, J. M.; Lee, M. M.; Wu, J. Q.
10.1101/2020.08.12.246660 — cancer biology — Posted on 2020-09-30
43 Single-cell landscape of bone marrow metastases in human neuroblastoma unraveled by deep multiplex imaging
Lazic, D.; Kromp, F.; Kirr, M.; Mivalt, F.; Rifatbegovic, F.; Halbritter, F.; Bernkopf, M.; Bileck, A.; Ussowicz, M.; Ambros, I. M.; Ambros, P. F.; Gerner, C.; Ladenstein, R.; Ostalecki, C.; Taschner-Mandl, S.
10.1101/2020.09.30.321539 — cancer biology — Posted on 2020-09-30
45 The genotype-phenotype landscape of an allosteric protein
Tack, D. S.; Tonner, P. D.; Pressman, A.; Olson, N. D.; Levy, S. F.; Romantseva, E. F.; Alperovich, N.; Vasilyeva, O.; Ross, D.
10.1101/2020.09.30.320812 — biophysics — Posted on 2020-09-30
46 Malaria parasites differentially sense environmental elasticity during transmission
Ripp, J.; Kehrer, J.; Smyrnakou, X.; Tisch, N.; Ruiz de Almodovar, C.; Frischknecht, F.
10.1101/2020.09.29.319020 — biophysics — Posted on 2020-09-30
48 A robust mean and variance test with application tohigh-dimensional phenotypes
Staley, J. R.; Windmeijer, F.; Suderman, M.; Lyon, M. S.; Davey Smith, G.; Tilling, K.
10.1101/2020.02.06.926584 — bioinformatics — Posted on 2020-09-30
49 Computational identification of human biological processes and protein sequence motifs putatively targeted by SARS-CoV-2 proteins using protein-protein interaction networks
Nadeau, R.; Shahryari Fard, S.; Scheer, A.; Hashimoto-Roth, E.; Nygard, D.; Abramchuk, I.; Chung, Y.-E.; Bennett, S. A. L.; Lavallee-Adam, M.
10.1101/2020.09.29.318931 — bioinformatics — Posted on 2020-09-30
51 Effects of sheared chromatin length on ChIP-seq quality and sensitivity
Keller, C. A.; Heuston, E. F.; Giardine, B. M.; Long, M. R.; Miller, A.; Wixom, A. Q.; Anderson, S. M.; Bodine, D.; Hardison, R. C.
10.1101/2020.09.30.320697 — genomics — Posted on 2020-09-30
53 Transcriptome and interactome analyses identify the TP53 interacting gene RCCD1 as a candidate susceptibility gene at the 15p26.1 breast and ovarian cancer risk locus
Plummer, J. T.; Segato Dezem, F.; Chen, S.; Dhungana, S.; Wali, D.; Davis, B.; Kanska, J.; Safi, N.; Suo, J.-H.; Corona, R. I.; Schildkraut, J. M.; Pharoah, P. D.; Lawrenson, K.; Knott, S. R.; Freedman, M. L.; Kar, S. P.; Gayther, S. A.
10.1101/2020.09.29.319699 — genetics — Posted on 2020-09-30
54 CBX1 mutations cause a neurodevelopmental syndrome due to heterochromatin organizational alterations
Iwata-Otsubo, A.; Lindsay-Temple, S.; Dias, K.-R.; Zhu, Y.; Fiordaliso, S.; Su, C.; Ritter, A.; Baker, S. W.; Kuroda, Y.; Keena, B. A.; Grant, S. F.; Zackai, E.; Edwards, M.; Evans, C.-A.; Dulik, M. C.; Buckley, M. F.; Roscioli, T.; Izumi, K.
10.1101/2020.09.29.319228 — genetics — Posted on 2020-09-30
60 Cellular proteostasis decline in human senescence
Sabath, N.; Levy-Adam, F.; Younis, A.; Rozales, K.; Meller, A.; Hadar, S.; Soueid-Baumgarten, S.; Shalgi, R.
10.1101/860775 — molecular biology — Posted on 2020-09-30
62 Gut Microbiota-Targeted Diets Modulate Human Immune Status
Wastyk, H. C.; Fragiadakis, G. K.; Perelman, D.; Dahan, D.; Merrill, B. D.; Yu, F. B.; Topf, M.; Gonzalez, C.; Robinson, J. L.; Elias, J. E.; Sonnenburg, E.; Gardner, C. D.; Sonnenburg, J.
10.1101/2020.09.30.321448 — microbiology — Posted on 2020-09-30
65 The furin cleavage site of SARS-CoV-2 spike protein is a key determinant for transmission due to enhanced replication in airway cells.
Peacock, T. P.; Goldhill, D. H.; Zhou, J.; Baillon, L.; Frise, R.; Swann, O. C.; Kugathasan, R.; Penn, R.; Brown, J. C.; Sanchez-David, R. Y.; Braga, L.; Williamson, M. K.; Hassard, J. A.; Staller, E.; Hanley, B.; Osborn, M.; Giacca, M.; Davidson, A. D.; Matthews, D. A.; Barclay, W. S.
10.1101/2020.09.30.318311 — microbiology — Posted on 2020-09-30
66 Drought duration determines the recovery dynamics of rice root microbiomes
Santos-Medellin, C.; Liechty, Z.; Edwards, J.; Nguyen, B.; Huang, B.; Weimer, B. C.; Sundaresan, V.
10.1101/2020.09.29.314781 — microbiology — Posted on 2020-09-30
72 Multiple pathways to homothallism in closely related yeast lineages in the Basidiomycota
Cabrita, A.; David-Palma, M.; Brito, P. H.; Heitman, J.; Coelho, M. A.; Goncalves, P.
10.1101/2020.09.30.320192 — microbiology — Posted on 2020-09-30
74 Soluble mannose receptor induces pro-inflammatory macrophage activation andobesity-associated metaflammation
Embgenbroich, M.; van der Zande, H. J.; Hussaarts, L.; Schulte-Schrepping, J.; Pelgrom, L. R.; Garcia-Tardon, N.; Schlautmann, L.; Stoetzel, I.; Handler, K.; Lambooij, J. M.; Zawistowska-Deniziak, A.; Hoving, L.; de Ruiter, K.; Wijngaarden, M.; Pijl, H.; Willems van Dijk, K.; Everts, B.; van Harmelen, V.; Yazdanbakhsh, M.; Schultze, J. L.; Guigas, B.; Burgdorf, S.
10.1101/2020.09.29.315598 — immunology — Posted on 2020-09-30
75 BANCOVID, the first D614G variant mRNA-based vaccine candidate against SARS-CoV-2 elicits neutralizing antibody and balanced cellular immune response
Baray, J. C.; Khan, M. M. R.; Mahmud, A.; Islam, M. J.; Myti, S.; Ali, M. R.; Sarker, M. E. H.; Kumar, S.; Chowdhury, M. M. H.; Roy, R.; Islam, F.; Barman, U.; Khan, H.; Chakraborty, S.; Hossain, M. M.; Chowdhury, M. M. R.; Ghosh, P.; Mohiuddin, M.; Sultana, N.; Nag, K.
10.1101/2020.09.29.319061 — immunology — Posted on 2020-09-30
80 Intravital Deep-Tumor Single-Beam 2-, 3- and 4-Photon Microscopy
Bakker, G.-J.; Weischer, S.; Heidelin, J.; Andresen, V.; Beutler, M.; Friedl, P.
10.1101/2020.09.29.312827 — cancer biology — Posted on 2020-09-30
81 PD-L1 lncRNA splice promotes lung adenocarcinoma progression via enhancing c-Myc activity
Qu, s.; Jiao, Z.; Lu, G.; Yao, B.; Wang, T.; Rong, W.; Xu, J.; Fan, T.; Sun, X.; Yang, R.; Wang, J.; Yang, Z.; Xu, G.; Yan, X.; Wang, T.; liang, h.; Zen, K.
10.1101/2020.09.29.282541 — cancer biology — Posted on 2020-09-30
82 Hallmarks of Alpha- and Betacoronavirus non-structural protein 7+8 complexes
Krichel, B.; Bylapudi, G.; Schmidt, C.; Blanchet, C.; Schubert, R.; Brings, L.; Koehler, M.; Zenobi, R.; Svergun, D.; Lorenzen, K.; Madhugiri, R.; Ziebuhr, J.; Uetrecht, C.
10.1101/2020.09.30.320762 — biophysics — Posted on 2020-09-30
84 Mapping single-cell atlases throughout Metazoa unravels cell type evolution
Tarashansky, A. J.; Musser, J.; Khariton, M.; Li, P.; Arendt, D.; Quake, S. R.; Wang, B.
10.1101/2020.09.28.317784 — bioinformatics — Posted on 2020-09-30
85 Structural insights on the substrate-binding proteins of the Mycobacterium tuberculosis mammalian-cell-entry (Mce) 1 and 4 complexes
Asthana, P.; Singh, D.; Pedersen, J. S.; Hynönen, M. J.; Sulu, R.; Murthy, A. V.; Laitaoja, M.; Jänis, J.; W. Riley, L.; Venkatesan, R.
10.1101/2020.09.29.317909 — biochemistry — Posted on 2020-09-30
86 Reengineering the Specificity of the Highly Selective Clostridium botulinum Protease via Directed Evolution
Dyer, R. P.; Isoda, H. M.; Salcedo, G. S.; Speciale, G.; Fletcher, M. H.; Le, L. Q.; Liu, Y.; Malik, S. Z.; Vazquez-Cintron, E. J.; Chu, A. C.; Rupp, D. C.; Jacky, B.; Nguyen, T. T.; Steward, L. E.; Majumdar, S.; Brideau-Andersen, A. D.; Weiss, G. A.
10.1101/2020.09.29.319145 — biochemistry — Posted on 2020-09-30
88 Altered oligodendroglia and astroglia in chronic traumatic encephalopathy
Chancellor, K. B.; Chancellor, S. E.; Duke-Cohan, J. E.; Huber, B. R.; Stein, T. D.; Alvarez, V. E.; Okaty, B. W.; Dymecki, S. M.; McKee, A. C.
10.1101/2020.05.13.089086 — genomics — Posted on 2020-09-30
91 Transgenic pyrimethamine resistant Plasmodium berghei as a model for in vivo anti-DHFR drug testing
Koonyosying, P.; Jupatanakul, N.; Vanichtanankul, J.; Saeyang, T.; Pethrak, C.; Pengon, J.; Tipsuwan, W.; Yuthavong, Y.; Kamchonwongpaisan, S.; Uthaipibull, C.
10.1101/2020.09.30.281055 — microbiology — Posted on 2020-09-30
92 Inhibition of SARS-CoV-2 in Vero cell cultures by peptide-conjugated morpholino-oligomers.
Rosenke, K.; Leventhal, S.; Moulton, H.; Hatlevig, S.; Hawman, D.; Feldmann, H.; Stein, D. A.
10.1101/2020.09.29.319731 — microbiology — Posted on 2020-09-30
94 A human monoclonal antibody targeting a conserved pocket in the SARS-CoV-2 receptor-binding domain core
Fedry, J.; Hurdiss, D. L.; Wang, C.; Li, W.; Obal, G.; Drulyte, I.; Howes, S. C.; van Kuppeveld, F. J. M.; Förster, F.; Bosch, B. J.
10.1101/2020.09.30.318261 — immunology — Posted on 2020-09-30
96 SARS-CoV-2 and Malayan pangolin coronavirus infect human endoderm, ectoderm and induced lung progenitor cells
Xiang, K.; Hong, B.; Lai, X.; Chen, Y.; Luo, T.; An, X.; Song, L.; Zhuang, H.; Fan, H.; Li, T.; Tong, Y.-G.
10.1101/2020.09.25.313270 — microbiology — Posted on 2020-09-30
99 A kinetic ensemble of the Alzheimer's Aβ peptide
Löhr, T.; Kohlhoff, K.; Heller, G. T.; Camilloni, C.; Vendruscolo, M.
10.1101/2020.05.07.082818 — biophysics — Posted on 2020-09-30
100 Analysis of SARS-CoV-2 genomes from across Africa reveals potentially clinically relevant mutations.
Longjohn, M. N.; Egbule, O. S.; Danso, S. O.; Akujuru, E.; Ibubeleye, V. T.; Oweredaba, C. I.; Ogharanduku, T.; Manu, A.; Iweriebor, B. C.
10.1101/2020.09.08.287201 — bioinformatics — Posted on 2020-09-30
102 The COVID-19 PHARMACOME: Rational Selection of Drug Repurposing Candidates from Multimodal Knowledge Harmonization
Schultz, B. T.; Zaliani, A.; Ebeling, C.; Reinshagen, J.; Bojkova, D.; Lage-Rupprecht, V.; Karki, R.; Lukassen, S.; Gadiya, Y.; Ravindra, N. G.; Das, S.; Baksi, S.; Domingo-Fernandez, D.; Lentzen, M.; Strivens, M.; Raschka, T.; Cinatl, J.; DeLong, L. N.; Gribbon, P.; Geisslinger, G.; Ciesek, S.; van Dijk, D.; Gardner, S.; Tom Kodamullil, A.; Froehlich, H.; Peitsch, M.; Jacobs, M.; Hoeng, J.; Eils, R.; Claussen, C.; Hofmann-Apitius, M.
10.1101/2020.09.23.308239 — bioinformatics — Posted on 2020-09-30
103 Genome Diversity in Ukraine
Oleksyk, T. K.; Wolfsberger, W. W.; Weber, A.; Shchubelka, K.; Oleksyk, O. T.; Levchuk, O.; Patrus, A.; Lazar, N.; Castro-Marquez, S. O.; Boldyzhar, P.; Urbanovych, A.; Stakhovska, V.; Malyar, K.; Chervyakova, S.; Podoroha, O.; Kovalchuk, N.; Hasynets, Y.; Rodriguez-Flores, J. L.; Medley, S.; Battistuzzi, F. U.; Liu, R.; Hou, Y.; Chen, S.; Yang, H.; Yeager, M.; Dean, M.; Mills, R. E.; Smolanka, V.
10.1101/2020.08.07.238329 — genomics — Posted on 2020-09-30
106 A small-molecule oral agonist of the human glucagon-like peptide-1 receptor
Griffith, D. A.; Edmonds, D. J.; Fortin, J.-P.; Kalgutkar, A. S.; Kuzmiski, J. B.; Loria, P. M.; Saxena, A. R.; Bagley, S. W.; Buckeridge, C.; Curto, J. M.; Derksen, D. R.; Dias, J. M.; Griffor, M. C.; Han, S.; Jackson, V. M.; Lettiere, D. J.; Limberakis, C.; Liu, Y.; Mathiowetz, A. M.; Piotrowski, D. W.; Price, D. A.; Ruggeri, R. B.; Tess, D. A.
10.1101/2020.09.29.319483 — pharmacology and toxicology — Posted on 2020-09-30
109 Temporal emergence of age-associated changes in cognitive and physical function in vervets (Chlorocebus aethiops sabaeus)
Frye, B. M.; Valure, P. M.; Craft, S.; Baxter, M. G.; Scott, C.; Wise-Walden, S.; Bissinger, D.; Register, H. M.; Copeland, C.; Jorgensen, M. J.; Justice, J. N.; Kritchevsky, S. B.; Register, T. C.; Shively, C. A.
10.1101/2020.09.28.313460 — animal behavior and cognition — Posted on 2020-09-30
110 Addiction-associated genetic variants implicate brain cell type- and region-specific cis-regulatory elements in addiction neurobiology
Srinivasan, C.; Phan, B. N.; Lawler, A. J.; Ramamurthy, E.; Kleyman, M.; Brown, A. R.; Kaplow, I. M.; Wirthlin, M. E.; Pfenning, A. R.
10.1101/2020.09.29.318329 — genomics — Posted on 2020-09-30
113 Synaptic correlates of associative fear memory in the lateral amygdala
Choi, D. I.; Kim, J.-i.; Kim, J.; Lee, H.; Choi, J. E.; Park, P.; Jung, H.; Kaang, B.-K.
10.1101/2020.09.28.317800 — neuroscience — Posted on 2020-09-30
116 A Human Aggression Pheromone Elicits a Sexually Dimorphic Behavioral and Brain Response
Mishor, E.; Amir, D.; Weiss, T.; Honigstein, D.; Weissbrod, A.; Livne, E.; Gorodisky, L.; Karagach, S.; Ravia, A.; Snitz, K.; Karawani, D.; Zirler, R.; Weissgross, R.; soroka, T.; Endevelt-Shapira, Y.; Agron, S.; Rozenkrantz, L.; Reshef, N.; Furman-Haran, E.; Breer, H.; Strotmann, J.; Sobel, N.
10.1101/2020.09.29.318287 — neuroscience — Posted on 2020-09-30
117 A super-resolution protocol to correlate structural underpinnings of fast second-messenger signalling in primary cell types
Hurley, M. E.; Sheard, T. M. D.; Norman, R.; Kirton, H. M.; Shah, S. S.; Pervolaraki, E.; Yang, Z.; Gamper, N.; White, E.; Steele, D.; Jayasinghe, I.
10.1101/2020.09.29.319400 — biophysics — Posted on 2020-09-30
118 PYMEVisualize: an open-source tool for exploring 3D super-resolution data
Marin, Z.; Graff, M.; Barentine, A. E. S.; Soeller, C.; Chung, K. K. H.; Fuentes, L. A.; Baddeley, D.
10.1101/2020.09.29.315671 — biophysics — Posted on 2020-09-30
119 Implantable photonic neural probes for light-sheet fluorescence brain imaging
Sacher, W. D.; Chen, F.-D.; Moradi-Chameh, H.; Luo, X.; Fomenko, A.; Shah, P.; Lordello, T.; Liu, X.; Felts Almog, I.; Straguzzi, J. N.; Fowler, T. M.; Jung, Y.; Hu, T.; Jeong, J.; Lozano, A. M.; Guo-Qiang Lo, P.; Valiante, T. A.; Moreaux, L. C.; Poon, J. K. S.; Roukes, M. L.
10.1101/2020.09.30.317214 — bioengineering — Posted on 2020-09-30
123 Inoculation by mosquito induces durable differences in serological profile in non-human primates infected with DENV1
Rajan, J.; McCracken, M.; Mandel-Brehm, C.; Gromowski, G.; Pollett, S.; Jarman, R. G.; DeRisi, J.
10.1101/2020.09.28.315218 — immunology — Posted on 2020-09-30
124 Natural selection and the advantage of recombination
Gerrish, P. J.; Galeota-Sprung, B.; Cordero, F.; Sniegowski, P. D.; Colato, A.; Hengartner, N. W.; Vejalla, V.; Chevalier, J.; Ycart, B.
10.1101/2020.08.28.271486 — evolutionary biology — Posted on 2020-09-30
125 Simvastatin Therapy Attenuates Memory Deficits that Associate to Brain Monocyte Infiltration in Chronic Hypercholesterolemic ApoE-/- Mice
Don-Doncow, N.; Matthes, F.; Matuskova, H.; Rattik, S.; Vanherle, L.; Kragh Petersen, S.; Hartlova, A.; Meissner, A.
10.1101/2020.05.15.098236 — physiology — Posted on 2020-09-30
127 Identification of PDE6D as a potential target of sorafenib via PROTAC technology
Li, Y.; Meng, Q.; Wang, P.; Liu, X.; Fu, Q.; Xie, Y.; Zhou, Y.; Qi, X.; Huang, N.
10.1101/2020.05.06.079947 — biochemistry — Posted on 2020-09-30
131 Different complement immune pathways mediate innate and learned aversion
Westacott, L. J.; Humby, T.; Naan, N.; Brain, S. A.; Bush, E.-L.; Toneva, M.; Baloc, A.-I.; Lander, N.; Moon, A. L.; Reddaway, J.; Owen, M. J.; Hall, J.; Hughes, T. R.; Morgan, B. P.; Gray, W. P.; Wilkinson, L.
10.1101/685537 — neuroscience — Posted on 2020-09-30
133 NHR-8 regulated P-glycoproteins uncouple xenobiotic stress resistance from longevity in chemosensory C. elegans mutants
Guerrero, G. A.; Hartman, M. D.; Schilling, K.; Mayr, F. A. M. C.; Lu, R.; Benayoun, B. A.; Denzel, M. S.
10.1101/823302 — genetics — Posted on 2020-09-29
134 Effect of sanitation improvements on soil-transmitted helminth eggs in courtyard soil from rural Bangladesh: Evidence from a cluster-randomized controlled trial
Kwong, L.; Sen, D.; Islam, S.; Shahriar, S.; Benjamin-Chung, J.; Arnold, B. F.; Hubbard, A.; Parvez, S. M.; Unicomb, L.; Rahman, M.; Colford, J. M.; Luby, S. P.; Ercumen, A.
10.1101/2020.09.29.318097 — ecology — Posted on 2020-09-29
137 An evolutionarily diverged mitochondrial protein controls biofilm growth and virulence in Candida albicans
Mamouei, Z.; Singh, S.; Lemire, B.; Gu, Y.; Alqarihi, A.; Nabeela, S.; Li, D.; Ibrahim, A.; Uppuluri, P.
10.1101/2020.09.29.318048 — microbiology — Posted on 2020-09-29
140 Tumor Necrosis Factor and Schistosoma mansoni egg antigen Omega-1 shape distinct aspects of the early egg-induced granulomatous response
Ramakrishnan, L.; Takaki, K. K.; Roca, F. J.; Schramm, G.; Wilbers, R. H. P.; Ittiprasert, W.; Brindley, P. J.; Rinaldi, G.; Berriman, M.; Pagan, A.
10.1101/2020.09.29.318105 — microbiology — Posted on 2020-09-29
141 The functional and phenotypic diversity of single T-cell infiltrates in human colorectal cancer as correlated with clinical outcome
Masuda, K.; Kornberg, A.; Lin, S.; Ho, P.; Secener, K.; Suek, N.; Bacarella, A. M.; Ingham, M.; Rosario, V.; Al-Masrou, A. M.; Lee-Kong, S. A.; Kiran, P. R.; Yan, K. S.; Stoeckius, M.; Smibert, P.; Oberstein, P. E.; Sims, P. A.; Han, A.
10.1101/2020.09.27.313445 — immunology — Posted on 2020-09-29
143 New traps for the capture of Aedes aegypti (Linnaeus) and Aedes albopictus (Skuse) (Diptera: Culicidae) eggs and adults
Rossi da Silva, K.; Ribeiro da Silva, W.; Silva, B. P.; Arcos, A. N.; da Silva Ferreira, F. A.; Soares-da-Silva, J.; Pontes, G. O.; Roque, R. A.; Tadei, W. P.; Navarro-Silva, M. A.; zequi, j. c.
10.1101/2020.09.29.318113 — zoology — Posted on 2020-09-29
145 Ex vivo Demonstration of Functional Deficiencies in Popliteal Lymphatic Vessels from TNF-Tg Mice with Inflammatory Arthritis
Scallan, J. P.; Bouta, E. M.; Rahimi, H.; Kenney, H. M.; Ritchlin, C. T.; Davis, M. J.; Schwarz, E. M.
10.1101/2020.09.22.309070 — pathology — Posted on 2020-09-29
146 Fibrous caps in atherosclerosis form by Notch-dependent mechanisms shared with arterial media development
Martos Rodriguez, C. J.; Albarran-Juarez, J.; Morales Cano, D.; Caballero, A.; MacGrogan, D.; de la Pompa, J. L.; Carramolino, L.; Bentzon, J. F.
10.1101/2020.09.28.316984 — pathology — Posted on 2020-09-29
147 FtsW exhibits distinct processive motions driven by either septal cell wall synthesis or FtsZ treadmilling in E. coli
Yang, X.; McQuillen, R.; Lyv, Z.; Phillips-Mason, P.; De La Cruz, A.; McCausland, J. W.; Liang, H.; DeMeester, K. E.; Santiago, C. C.; Grimes, C. L.; de Boer, P.; Xiao, J.
10.1101/850073 — biophysics — Posted on 2020-09-29
149 Protein sequence design with a learned potential
Anand-Achim, N.; Eguchi, R. R.; Derry, A.; Altman, R. B.; Huang, P.
10.1101/2020.01.06.895466 — bioinformatics — Posted on 2020-09-29
150 CDK-Mediated Phosphorylation of FANCD2 Promotes Mitotic Fidelity
Cantres-Velez, J.; Blaize, J.; Vierra, D.; Boisvert, R.; Garzon, J.; Piraino, B.; Tan, W.; Deans, A.; Howlett, N. G.
10.1101/2020.09.29.318055 — biochemistry — Posted on 2020-09-29
151 Discovery and engineering of small SlugCas9 with broad targeting range and high specificity and activity
Hu, Z.; Zhang, C.; Wang, S.; Wei, J.; Li, M.; Hou, L.; Liu, H.; Liu, D.; Lan, F.; Lu, D.; Wang, H.; Li, J.; Wang, Y.
10.1101/2020.09.29.316661 — genetics — Posted on 2020-09-29
158 Amyloid beta acts synergistically as a pro-inflammatory cytokine
LaRocca, T. J.; Cavalier, A. N.; Roberts, C. M.; Lemieux, M. R.; Link, C. D.
10.1101/2020.09.28.316927 — molecular biology — Posted on 2020-09-29
159 Distinct prefrontal top-down circuits differentially modulate sensorimotor behavior
Huda, R.; Sipe, G. O.; Breton-Provencher, V.; Cruz, K. G.; Pho, G.; Adam, E.; Gunter, L.; Sullins, A.; Wickersham, I. R.; Sur, M.
10.1101/307009 — neuroscience — Posted on 2020-09-29
161 Sex-specific retinal anomalies induced by chronic social stress in mice
Arsenault, E.; Lavigne, A.-A.; Mansouri, S.; Francis, K.; Bittar, T. P.; Quessy, F.; Abdallah, K.; Barbeau, A.; Hebert, M.; Labonte, B.
10.1101/2020.09.28.317230 — neuroscience — Posted on 2020-09-29
165 Epigenomic features related to microglia are associated with attenuated effect of APOE ε4 on Alzheimer's disease risk in humans
Ma, Y.; Yu, L.; Olah, M.; Smith, R.; Oatman, S. R.; Allen, M.; Pishva, E.; Zhang, B.; Menon, V.; Ertekin-Taner, N.; Lunnon, K.; Bennett, D. A.; Klein, H.-U.; De Jager, P.
10.1101/2020.09.28.317156 — neuroscience — Posted on 2020-09-29
166 Impaired online error-correction disrupts synchronization to external events in autism
Vishne, G.; Jacoby, N.; Malinovitch, T.; Epstein, T.; Frenkel, O.; Ahissar, M.
10.1101/2020.09.28.316828 — neuroscience — Posted on 2020-09-29
172 A synthetic small molecule stalls pre-mRNA splicing by promoting an early-stage U2AF2-RNA complex
Chatrikhi, R.; Feeney, C. F.; Pulvino, M. J.; Alachouzos, G.; MacRae, A. J.; Falls, Z.; Rai, S.; Brennessel, W. W.; Jenkins, J. L.; Walter, M. J.; Graubert, T. A.; Samudrala, R.; Jurica, M. S.; Frontier, A. J.; Kielkopf, C. L.
10.1101/2020.09.28.317727 — biochemistry — Posted on 2020-09-29
173 Chromosome-level genome assemblies of the malaria vectors Anopheles coluzzii and Anopheles arabiensis
Zamyatin, A.; Avdeyev, P.; Liang, J.; Sharma, A.; Chen, C.; Lukyanchikova, V.; Alexeev, N.; Tu, Z.; Alekseyev, M. A.; Sharakhov, I. V.
10.1101/2020.09.29.318477 — genomics — Posted on 2020-09-29
174 Genetic architecture of gene regulation in Indonesian populations identifies QTLs associated with local ancestry and archaic introgression
Natri, H. M.; Hudjashov, G.; Jacobs, G.; Kusuma, P.; Saag, L.; Darusallam, C. C.; Metspalu, M.; Sudoyo, H.; Cox, M. P.; Gallego Romero, I.; Banovich, N. E.
10.1101/2020.09.25.313726 — genomics — Posted on 2020-09-29
175 Comparative transcriptomics and host-specific parasite gene expression profiles inform on drivers of proliferative kidney disease
Faber, M.; Yoon, S.; Shaw, S.; de Paiva Alves, E.; Wang, B.; Zhitao, Q.; Okamura, B.; Hartikainen, H.; Secombes, C. J.; HOLLAND, J. W.
10.1101/2020.09.28.312801 — genomics — Posted on 2020-09-29
178 On-site eDNA detection of species using ultra-rapid mobile PCR
Doi, H.; Watanabe, T.; Nishizawa, N.; Saito, T.; Nagata, H.; Kameda, Y.; Ikeda, K.; Maki, N.; Fukuzawa, T.
10.1101/2020.09.28.314625 — ecology — Posted on 2020-09-29
179 Consistent variations in personality traits and their potential for genetic improvement in the biocontrol agent Trichogramma evanescens
Lartigue, S.; Yalaoui, M.; Belliard, J.; Caravel, C.; Jeandroz, L.; Groussier, G.; Calcagno, V.; Louapre, P.; Dechaume-Moncharmont, F.-X.; Malausa, T.; Moreau, J.
10.1101/2020.08.21.257881 — ecology — Posted on 2020-09-29
181 Restructured mitochondrial-nuclear interaction in P. falciparum dormancy and persister survival of artemisinin exposure
Connelly, S. V.; Manzella-Lapeira, J.; Levine, Z. C.; Brzostowski, J.; Krymskaya, L.; Rahman, R. S.; Sa, J. M.; Wellems, T. E.
10.1101/2020.09.28.314435 — microbiology — Posted on 2020-09-29
184 Metabolomic signature of the maternal microbiota in the fetus
Pessa-Morikawa, T.; Husso, A.; Kärkkäinen, O.; Koistinen, V.; Iivanainen, A.; Niku, M.
10.1101/2020.09.28.317081 — microbiology — Posted on 2020-09-29
186 The Global Architecture Shaping the Heterogeneity and Tissue-Dependency of the MHC Class I Immunopeptidome is Evolutionarily Conserved
Kubiniok, P.; Marcu, A.; Bichmann, L.; Kuchenbecker, L.; Schuster, H.; Hamelin, D.; Despault, J.; Kovalchik, K.; Wessling, L.; Kohlbacher, O.; Stevanovic, S.; Hans-Georg, R.; Neidert, M. C.; Sirois, I.; Caron, E.
10.1101/2020.09.28.317750 — immunology — Posted on 2020-09-29
187 Predicting age and clinical risk from the neonatal connectome
Taoudi-Benchekroun, Y.; Christiaens, D.; Grigorescu, I.; Schuh, A.; Pietsch, M.; Chew, A.; Harper, N.; Falconer, S.; Poppe, T.; Hughes, E.; Hutter, J.; Price, A. N.; Tournier, J.-D.; Cordero-Grande, L.; Counsell, S. J.; Rueckert, D.; Arichi, T.; Hajnal, J. V.; Edwards, A. D.; Deprez, M.; Batalle, D.
10.1101/2020.09.28.317180 — neuroscience — Posted on 2020-09-29
190 Analysis of Circulating Exosomes Reveals a Peripheral Signature of Astrocytic Pathology in Schizophrenia
Ranganathan, M.; Rahman, M.; Ganesh, S.; D'Souza, D. C.; Skosnik, P. D.; Radhakrishnan, R.; Pathania, S.; Mohanakumar, T.
10.1101/2020.02.18.955013 — neuroscience — Posted on 2020-09-29
191 Identification of a unique ZIP transporter involved in zinc uptake via the arbuscular mycorrhizal fungal pathway
Watts-Williams, S. J.; Wege, S.; Ramesh, S. A.; Berkowitz, O.; Gilliham, M.; Whelan, J.; Tyerman, S. D.
10.1101/2020.09.28.317669 — plant biology — Posted on 2020-09-29
193 Insertional mutagenesis defines drivers and evolutionary relationships in pancreatic cancer metastasis
Govindaraju, S.; Maurin, M.; Newberg, J. Y.; Jones, D. J.; Lee, H.; Markovitz, J. E.; Mann, M. B.; Black, M. A.; Mann, K. M.
10.1101/2020.09.28.317701 — cancer biology — Posted on 2020-09-29
194 Interconversion of unexpected thiol states affects stability, structure and dynamics in engineered antibody for site-specific conjugation
Orozco, C. T.; Edgeworth, M. J.; Devine, P. W. A.; Hines, A. R.; Cornwell, O.; Wang, X.; Phillips, J. J.; Ravn, P.; Jackson, S. E.; Bond, N. J.
10.1101/2020.09.28.317339 — biophysics — Posted on 2020-09-29
195 A deep learning algorithm to translate and classify cardiac electrophysiology: From iPSC-CMs to adult cardiac cells
Aghasafari, P.; Yang, P.-C.; Kernik, D. C.; Sakamoto, K.; Kanda, Y.; Kurokawa, J.; Vorobyov, I.; Clancy, C. E.
10.1101/2020.09.28.317461 — bioinformatics — Posted on 2020-09-29
196 A Probabilistic and Anisotropic Failure Metric for Ascending Thoracic Aortic Aneurysm Risk Stratification
Liu, M.; Liang, L.; Zou, Q.; Ismail, Y.; Lou, X.; Iannucci, G.; Chen, E. P.; Leshnower, B. G.; Elefteriades, J. A.; Sun, W.
10.1101/2020.09.28.317255 — bioengineering — Posted on 2020-09-29
204 The roseoloviruses downregulate the protein tyrosine phosphatase PTPRC(CD45)
Whyte, M. L.; Smith, K. A.; Buchberger, A.; Berg Luecke, L.; Handayani Tjan, L.; Mori, Y.; Gundry, R.; Hudson, A. W.
10.1101/2020.09.29.318709 — microbiology — Posted on 2020-09-29
206 The composition of the microbiota in the full-term fetal gut and amniotic fluid: a bovine caesarean section study
Husso, A.; Lietaer, L.; Pessa-Morikawa, T.; Grönthal, T.; Govaere, J.; Van Soom, A.; Iivanainen, A.; Opsomer, G.; Niku, M.
10.1101/2020.09.28.309476 — microbiology — Posted on 2020-09-29
208 Population structure, biogeography and transmissibility of Mycobacterium tuberculosis
Freschi, L.; Vargas, R.; Hussain, A.; Mostofa Kamal, S. M.; Skrahina, A.; Tahseen, S.; Ismail, N.; Barbova, A.; Niemann, S.; Cirillo, D. M.; Dean, A. S.; Zignol, M.; Farhat, M. R.
10.1101/2020.09.29.293274 — microbiology — Posted on 2020-09-29
209 AcrIIA22 is a novel anti-CRISPR that impairs SpyCas9 activity by relieving DNA torsion of target plasmids
Forsberg, K. J.; Schmidtke, D. T.; Werther, R.; Hausman, D.; Stoddard, B. L.; Kaiser, B. K.; Malik, H. S.
10.1101/2020.09.28.317578 — microbiology — Posted on 2020-09-29
210 Recombination in enteroviruses is a ubiquitous event independent of sequence homology and RNA structure
Alnaji, F. G.; Bentley, K.; Pearson, A.; Woodman, A.; Moore, J. D.; Fox, H.; Macadam, A.; Evans, D.
10.1101/2020.09.29.319285 — microbiology — Posted on 2020-09-29
211 Mechanisms underlying proximity between oral commensal bacteria
Perera, D.; McLean, A.; Morillo Lopez, V.; Cloutier-Leblanc, K.; Almeida, E.; Cabana, K.; Mark Welch, J. L.; Ramsey, M. M.
10.1101/2020.09.29.318816 — microbiology — Posted on 2020-09-29
213 Phenology and function in lycopod-Mucoromycotina symbiosis
Hoysted, G. A.; Bidartondo, M. I.; Duckett, J. G.; Pressel, S.; Field, K. J.
10.1101/2020.09.28.316760 — plant biology — Posted on 2020-09-29
214 Deubiquitinase UCHL1 Maintains Protein Homeostasis through PSMA7-APEH-Proteasome Axis in High-Grade Serous Ovarian Carcinoma
Tangri, A.; Lighty, K.; Loganathan, J.; Mesmar, F.; Podicheti, R.; Zhang, C.; Iwanicki, M.; Nakshatri, H.; Mitra, S.
10.1101/2020.09.28.316810 — cancer biology — Posted on 2020-09-29
215 EPI Distortion Correction is Easy and Useful, and You Should Use It: A case study with toddler data
Roopchansingh, V.; French, J. J.; Nielson, D. M.; Reynolds, R. C.; Glen, D. R.; D'Souza, P.; Taylor, P. A.; Cox, R. W.; Thurm, A. E.
10.1101/2020.09.28.306787 — biophysics — Posted on 2020-09-29
216 Pinching the cortex of live cells reveals thickness instabilities caused by Myosin II motors
LAPLAUD, V.; Levernier, N.; Pineau, J.; San-Roman, M.; Barbier, L.; Saez, P. J.; Lennon-Dumenil, A.-M.; Vargas, P.; Kruse, K.; DU ROURE, O.; Piel, M.; Heuvingh, J.
10.1101/2020.09.28.316729 — biophysics — Posted on 2020-09-29
217 The extent of protein hydration dictates the preference for heterogeneous or homogeneous nucleation generating either parallel or antiparallel β-sheet α-synuclein aggregates
Camino, J. D.; Gracia, P.; Chen, S. W.; Sot, J.; de la Arada, I.; Sebastian, V.; Arrondo, J. L. R.; Goni, F.; Dobson, C. M.; Cremades, N.
10.1101/2020.09.28.315325 — biophysics — Posted on 2020-09-29
218 Interpreting blood GLUcose data with R package iglu
Broll, S.; Urbanek, J.; Buchanan, D.; Chun, E.; Muschelli, J.; Punjabi, N.; Gaynanova, I.
10.1101/2020.09.28.310482 — bioinformatics — Posted on 2020-09-29
220 Tethering-facilitated DNA 'opening' and complementary roles of β-hairpin motifs in the Rad4/XPC DNA damage sensor protein
Paul, D.; Mu, H.; Tavakoli, A.; Dai, Q.; Chen, X.; Chakraborty, S.; He, C.; Ansari, A.; Broyde, S.; Min, J. H.
10.1101/2020.09.28.313049 — biochemistry — Posted on 2020-09-29
221 Light-induced modulation of DNA recognition by the Rad4/XPC damage sensor protein
Tavakoli, A.; Paul, D.; Mu, H.; Kuchlyan, J.; Baral, S.; Ansari, A.; Broyde, S.; Min, J. H.
10.1101/2020.09.28.313114 — biochemistry — Posted on 2020-09-29
222 Probabilistic mapping of human functional brain networks identifies regions of high group consensus
Dworetsky, A.; Seitzman, B. A.; Adeyemo, B.; Neta, M.; Coalson, R. S.; Petersen, S. E.; Gratton, C.
10.1101/2020.09.28.313791 — neuroscience — Posted on 2020-09-29
225 SARS-CoV-2 D614G Variant Exhibits Enhanced Replication ex vivo and Earlier Transmission in vivo
Hou, Y. J.; Chiba, S.; Halfmann, P.; Ehre, C.; Kuroda, M.; Dinnon, K. H.; Leist, S. R.; Schäfer, A.; Nakajima, N.; Takahashi, K.; Lee, R. E.; Mascenik, T. M.; Edwards, C. E.; Tse, L. V.; Boucher, R. C.; Randell, S. H.; Suzuki, T.; Gralinski, L. E.; Kawaoka, Y.; Baric, R. S.
10.1101/2020.09.28.317685 — microbiology — Posted on 2020-09-29
226 Susceptibility of midge and mosquito vectors to SARS-CoV-2 by natural route of infection
Balaraman, V.; Drolet, B. S.; Gaudreault, N. N.; Wilson, W. C.; Owens, J.; Bold, D.; Swanson, D. A.; Jasperson, D. C.; Noronha, L. E.; Richt, J. A.; Mitzel, D.
10.1101/2020.09.29.317289 — microbiology — Posted on 2020-09-29
227 Prime-boost vaccination of mice and Rhesus macaques with two novel adenovirus vectored COVID-19 vaccine candidates
Luo, S.; Zhang, P.; Li, B.; Yang, C.; Liang, C.; Wang, Q.; Zhang, L.; Tang, X.; Li, J.; Hou, S.; Zeng, J.; Fu, Y.; Allain, J.-P.; Li, T.; Zhang, Y.; Li, C.
10.1101/2020.09.28.311480 — immunology — Posted on 2020-09-29
228 De Novo Discovery of High Affinity Peptide Binders for the SARS-CoV-2 Spike Protein
Pomplun, S.; Jbara, M.; Quartararo, A. J.; Zhang, G.; Brown, J. S.; Lee, Y.-C.; Ye, X.; Hanna, S.; Pentelute, B. L.
10.1101/2020.09.29.317131 — bioengineering — Posted on 2020-09-29
229 Cocaine causes rapid remodeling of dopaminergic axons, synapses, and mitochondria
Wildenberg, G. A.; Sorokina, A. M.; Koranda, J.; Monical, A.; Heer, C.; Sheffield, M.; Zhuang, X.; McGehee, D. S.; Kasthuri, N.
10.1101/2020.09.29.318881 — neuroscience — Posted on 2020-09-29
232 An evolutionary portrait of the progenitor SARS-CoV-2 and its dominant offshoots in COVID-19 pandemic
Kumar, S.; Tao, Q.; Weaver, S.; Sanderford, M. D.; Caraballo, M.; Sharma, S.; Kosakovsky Pond, S. L.; Miura, S.
10.1101/2020.09.24.311845 — evolutionary biology — Posted on 2020-09-29
233 Discovery and Development of Human SARS-CoV-2 Neutralizing Antibodies using an Unbiased Phage Display Library Approach
Cao, X.; Maruyama, J.; Zhou, H.; Kerwin, L.; Sattler, R.; Manning, J. T.; Johnson, S.; Richards, S.; Li, Y.; Shen, W.; Blair, B.; Du, N.; Morais, K.; Lawrence, K.; Lu, L.; Pai, C.-I.; Li, D.; Brunswick, M.; Zhang, Y.; Ji, H.; Paessler, S.; Allen, R. D.
10.1101/2020.09.27.316174 — microbiology — Posted on 2020-09-29
234 Structural variant evolution after telomere crisis
Dewhurst, S. M.; Yao, X. M.; Rosiene, J.; Tian, H.; Behr, J.; Bosco, N.; Takai, K.; de Lange, T.; Imielinski, M.
10.1101/2020.09.29.318436 — genomics — Posted on 2020-09-29
238 The impact of size on particle drainage dynamics and antibody response
Zinkhan, S.; Ogrina, A.; Balke, I.; Resevica, G.; Zeltins, A.; de Brot, S.; Lipp, C.; Chang, X.; Zha, L.; Vogel, M.; Bachmann, M. F.; Mohsen, M. O.
10.1101/2020.09.28.316612 — immunology — Posted on 2020-09-29
242 SeeCiTe: a method to assess CNV calls from SNP arrays using trio data
Lavrichenko, K.; Helgeland, O.; Njolstad, P. R.; Jonassen, I.; Johansson, S.
10.1101/2020.09.28.316372 — bioinformatics — Posted on 2020-09-29
248 An epigenetic clock to estimate the age of living beluga whales
Bors, E. K.; Baker, C. S.; Wade, P. R.; ONeill, K.; Shelden, K. E.; Thompson, M. J.; Fei, Z.; Jarman, S.; Horvath, S.
10.1101/2020.09.28.317610 — developmental biology — Posted on 2020-09-29
250 When DNA gets in the way in RNA-seq experiments, a sequel
Verwilt, J.; Giraldez, M. D.; Trypsteen, W.; Van Paemel, R.; De Preter, K.; Mestdagh, P.; Vandesompele, J.
10.1101/2020.09.28.316265 — molecular biology — Posted on 2020-09-29
253 FRUITFULL-like genes regulate flowering time and inflorescence architecture in tomato
Jiang, X.; Lubini, G.; Hernandes, J.; Rijnsburger, K.; Veltkamp, V.; de Maagd, R. A.; Angenent, G. C.; Bemer, M.
10.1101/2020.09.28.316562 — plant biology — Posted on 2020-09-29
254 TRAIL signalling promotes entosis in colorectal cancer
Bozkurt, E.; Dussmann, H.; Salvucci, M.; Cavanagh, B.; Van Schaeybroeck, S.; Longley, D. B.; Martin, S. J.; Prehn, J. H. M.
10.1101/2020.09.29.315317 — cancer biology — Posted on 2020-09-29
256 An evolutionarily diverged mitochondrial protein controls biofilm growth and virulence in Candida albicans
Mamouei, Z.; Singh, S.; Lemire, B.; Gu, Y.; Alqarihi, A.; Nabeela, S.; Li, D.; Ibrahim, A.; Uppuluri, P.
10.1101/2020.09.29.318048 — microbiology — Posted on 2020-09-29
258 Single cell analysis of colorectal cancer identifies mitogen-activated protein kinase as a key driver of tumor cell plasticity
Uhlitz, F.; Bischoff, P.; Peidli, S.; Sieber, A.; Obermayer, B.; Blanc, E.; Trinks, A.; Luethen, M.; Ruchiy, Y.; Mamlouk, S.; Arsie, R.; Wei, T.-T.; Klotz-Noack, K.; Schwarz, R.; Sawitzki, B.; Kamphues, C.; Beule, D.; Landthaler, M.; Sers, C.; Horst, D.; Bluthgen, N.; Morkel, M.
10.1101/2020.01.10.901579 — cancer biology — Posted on 2020-09-29
259 Regulation of RUVBL1-RUVBL2 AAA-ATPases by the nonsense-mediated mRNA decay factor DHX34, as evidenced by Cryo-EM
Llorca, O.; Lopez-Perrote, A.; Hug, N.; Gonzalez-Corpas, A.; Rodriguez, C. F.; Serna, M.; Garcia-Martin, C.; Boskovic, J.; Fernandez-Leiro, R.; Caceres, J. F.
10.1101/2020.09.28.317487 — biophysics — Posted on 2020-09-29
260 MonaGO: a novel Gene Ontology enrichment analysis visualisation system
Xin, Z.; Cai, Y.; Dang, L. T.; Burke, H. M. S.; Revote, J.; Nim, H. T.; Li, Y.-F.; Ramialison, M.
10.1101/2020.09.27.316067 — bioinformatics — Posted on 2020-09-29
262 Signal separability in integrated neurophotonics
Yatsenko, D.; Moreaux, L. C.; Choi, J.; Tolias, A.; Shepard, K. L.; Roukes, M. L.
10.1101/2020.09.27.315556 — neuroscience — Posted on 2020-09-29
263 Environment-dependent behavioral traits and experiential factors shape addiction vulnerability
Fouyssac, M.; Puaud, M.; Ducret, E.; Marti-Prats, L.; Vanhille, N.; Ansquer, S.; Zhang, X.; Belin-Rauscent, A.; Giuliano, C.; Houeto, J.-L.; Everitt, B.; Belin, D.
10.1101/2020.04.12.038141 — neuroscience — Posted on 2020-09-29
265 Orbitofrontal lesion patients show an implicit approach bias to angry faces
Buades-Rotger, M.; Solbakk, A.-K.; Liebrand, M.; Endestad, T.; Funderud, I.; Siegwardt, P.; Enter, D.; Roelofs, K.; Kraemer, U. M.
10.1101/2020.06.21.162628 — neuroscience — Posted on 2020-09-29
268 A free boundary mechanobiological model of epithelial tissues
Tambyah, T. A.; Murphy, R. J.; Buenzli, P. R.; Simpson, M. J.
10.1101/2020.07.02.185686 — biophysics — Posted on 2020-09-29
269 Parental influences on offspring education: indirect genetic effects of non-cognitive skills
Demange, P. A.; Hottenga, J. J.; Abdellaoui, A.; Malanchini, M.; Domingue, B. W.; de Zeeuw, E. L.; Rimfeld, K.; Eley, T.; Boomsma, D. I.; van Bergen, E.; Breen, G.; Nivard, M. G.; Cheesman, R.
10.1101/2020.09.15.296236 — genetics — Posted on 2020-09-29
270 Epigenomic profiling of primate LCLs reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures
Garcia-Perez, R.; Esteller-Cucala, P.; Mas, G.; Lobon, I.; Di Carlo, V.; Kuhlwilm, M.; Riera, M.; Navarro, A.; Blancher, A.; Di Croce, L.; Gomez-Skarmeta, J. L.; Juan, D.; Marques-Bonet, T.
10.1101/2019.12.18.872531 — evolutionary biology — Posted on 2020-09-29
271 Characters of neoantigens in cancer immunotherapy
Bai, P.; Li, Y.; Zhou, Q.; Xia, J.; Wu, M.; Deng, H.; Kappler, J. W.; Marrack, P.; Zhou, Y.; Yin, L.
10.1101/700732 — cancer biology — Posted on 2020-09-29
272 Clustering of loci controlling species differences in male chemical bouquets of sympatric Heliconius butterflies
Byers, K. J. R. P.; Darragh, K.; Fernanda Garza, S.; Abondano Almeida, D.; Warren, I. A.; Rastas, P. M. A.; Merrill, R. M.; Schulz, S.; McMillan, W. O.; Jiggins, C. D.
10.1101/2020.06.03.131557 — evolutionary biology — Posted on 2020-09-29
276 A roadmap for the characterization of energy metabolism in human cardiomyocytes derived from induced pluripotent stem cells
Emanuelli, G.; Zoccarato, A.; Papadopoulos, A.; Chong, M.; Beretta, M.; Betteridge, K.; Streckfuss-Boemeke, K.; Shah, A.
10.1101/2020.09.28.316745 — cell biology — Posted on 2020-09-29
277 The natural axis of transmitter receptor distribution in the human cerebral cortex
Goulas, A.; Changeux, J.-P.; Wagstyl, K.; Amunts, K.; Palomero-Gallagher, N.; Hilgetag, C. C.
10.1101/2020.09.28.316646 — neuroscience — Posted on 2020-09-29
284 Impact of COVID-19 on Hospital Admission of Acute Stroke patients in Bangladesh
Hasan, A. T. M. H.; Das, S. C.; Islam, M. S.; Mansur, M.; Shawon, M. S. R.; Hassan, R.; Chowdhury, M. S. J. H.; Mondal, M. B. A.; Mohammad, Q. D.
10.1101/2020.09.28.316448 — neuroscience — Posted on 2020-09-28
286 Measuring effects of trainee professional development on research productivity: A cross-institutional meta-analysis
Brandt, P.; Sturzenegger Varvayanis, S.; Baas, T.; Bolgioni-Smith, A.; Alder, J.; Petrie, K. A.; Dominguez, I.; Brown, A. M.; Stayart, C. A.; Singh, H.; Van Wart, A.; Chow, C. S.; Mathur, A.; Schreiber, B. M.; Fruman, D. A.; Bowden, B.; Holmquist, C. E.; Arneman, D.; Hall, J. D.; Hyman, L. E.; Gould, K.; Chalkley, R.; Brennwald, P.; Layton, R.
10.1101/2020.09.28.316422 — scientific communication and education — Posted on 2020-09-28
287 Manage flowering time in Miscanthus and sugarcane to facilitate intra- and intergeneric crosses
Dong, H.; Clark, L.; Jin, X.; Anzoua, K.; Bagmet, L.; Chebukin, P.; Dzyubenko, E.; Dzyubenko, N.; Ghimire, B. K.; Heo, K.; Johnson, D. A.; Nagano, H.; Sabitov, A.; Peng, J.; Yamada, T.; Yoo, J. H.; Yu, C. Y.; Zhao, H.; Long, S. P.; Sacks, E.
10.1101/2020.09.28.316489 — plant biology — Posted on 2020-09-28
288 β-adrenergic control of sarcolemmal CaV1.2 abundance by small GTPase Rab proteins
del Villar, S. G.; Voelker, T. L.; Spooner, H. C.; Dickson, E. J.; Dixon, R. E.
10.1101/2020.09.28.317362 — physiology — Posted on 2020-09-28
290 Evolution of Modularity, Interactome and Functions of GIV/Girdin (CCDC88A) from Invertebrates to Vertebrates
Ear, J.; Ali Abd El-Hafeez, A.; Roy, S.; Ngo, T.; Rajapakse, N.; Choi, J.; Khandelwal, S.; Ghassemian, M.; McCaffrey, L.; Kufareva, I.; Sahoo, D.; Ghosh, P.
10.1101/2020.09.28.317172 — biochemistry — Posted on 2020-09-28
292 Meta-analysis of genome-wide DNA methylation and integrative OMICs in human skeletal muscle.
Voisin, S.; Jacques, M.; Landen, S.; Harvey, N. R.; Haupt, L. M.; Griffiths, L. R.; Gancheva, S.; Ouni, M.; Jahnert, M.; Ashton, K. J.; Coffey, V. G.; Thompson, J.-L. M.; Doering, T. M.; Gabory, A.; Junien, C.; Caiazzo, R.; Verkindt, H.; Pattou, F.; Raverdi, V.; Froguel, P.; Craig, J. M.; Blocquiaux, S.; Thomis, M.; Sharples, A. P.; Schurmann, A.; Roden, M.; Horvath, S.; Eynon, N.
10.1101/2020.09.28.315838 — genetics — Posted on 2020-09-28
293 Evaluating the fitness of PA/I38T-substituted influenza A viruses with reduced baloxavir susceptibility in a competitive mixtures ferret model
Lee, L. Y.; Zhou, J.; Koszalka, P.; Frise, R.; Farrukee, R.; Baba, K.; Miah, S.; Shishido, T.; Galiano, M.; Hashimoto, T.; Omoto, S.; Uehara, T.; Mifsud, E.; Collinson, N.; Kuhlbusch, K.; Clinch, B.; Wildum, S.; Barclay, W. S.; Hurt, A. C.
10.1101/2020.09.28.316620 — microbiology — Posted on 2020-09-28
294 Transcriptional and immunological analysis of the putative outer membrane protein and vaccine candidate TprL of Treponema pallidum
Haynes, A.; Fernandez, M.; Romeis, E.; Mitja, O.; Konda, K.; Vargas, S.; Eguiluz, M.; Caceres, C.; Klausner, J.; Giacani, L.
10.1101/2020.09.28.316414 — microbiology — Posted on 2020-09-28
295 Differential encoding in prefrontal cortex projection neuron classes across cognitive tasks
Lui, J. H.; Nguyen, N. D.; Grutzner, S. M.; Darmanis, S.; Peixoto, D.; Wagner, M. J.; Allen, W. E.; Kebschull, J. M.; Richman, E. B.; Ren, J.; Newsome, W. T.; Quake, S. R.; Luo, L.
10.1101/2020.03.14.991018 — neuroscience — Posted on 2020-09-28
297 A new model of decision processing in instrumental learning tasks
Miletic, S.; Boag, R. J.; Trutti, A. C.; Forstmann, B. U.; Heathcote, A.
10.1101/2020.09.12.294512 — neuroscience — Posted on 2020-09-28
298 Genetic structure of Photosystem II functionality in rice unraveled by GWAS analysis
Vilas, J. M.; Burgos, E.; Puig, M. L.; Colazo, J.; Livore, A.; Ruiz, O. A.; Carrari, F.; Rodriguez, A. A.; Maiale, S. J.
10.1101/2020.09.28.317479 — plant biology — Posted on 2020-09-28
299 Telomere length and TERT expression are associated with age in almond (Prunus dulcis)
D'Amico-Willman, K. M.; Anderson, E. S.; Gradziel, T. M.; Fresnedo Ramirez, J.
10.1101/2020.09.25.294074 — plant biology — Posted on 2020-09-28
300 Skeletal Phenotype and Mechanisms of Bone Loss in Winnie Mice as a Model for Inflammatory Bowel Disease
Al Saedi, A.; Sharma, S.; Bani Hassan, E.; Chen, L.; Ghasem-Zadeh, A.; Hassanzadeganroudsari, M.; Gooi, J.; Stavely, R.; Rajamaran, E.; Miao, D.; Nurgali, K.; Duque, G.
10.1101/2020.09.28.317495 — physiology — Posted on 2020-09-28
301 Medium-chain acyl-CoA dehydrogenase, a gatekeeper of mitochondrial function in glioblastoma multiforme
Puca, F.; Yu, F.; Bertolacci, C.; Pettazzoni, P.; Carugo, A.; Huang-Hobbs, E.; Liu, J.; Zanca, C.; Carbone, F.; Del Poggetto, E.; Gumin, J.; Dasgupta, P.; Seth, S.; Lang, F. F.; Sulman, E.; Lorenzi, P. L.; Tan, L.; Shan, M.; Tolstyka, Z. P.; Kachman, M.; Zhang, L.; Deem, A. K.; Genovese, G.; Scaglioni, P. P.; Lyssiotis, C. A.; Viale, A.; Draetta, G.
10.1101/2020.09.28.316554 — cancer biology — Posted on 2020-09-28
304 Understanding the origins of loss of protein function by analyzing the effects of thousands of variants on activity and abundance
Cagiada, M.; Johansson, K. E.; Valanciute, A.; Nielsen, S. V.; Hartmann-Petersen, R.; Yang, J. J.; Fowler, D. M.; Stein, A.; Lindorff-Larsen, K.
10.1101/2020.09.28.317040 — biophysics — Posted on 2020-09-28
307 A comprehensive phylogenetic analysis of the serpin superfamily
Spence, M. A.; Mortimer, M. D.; Buckle, A. M.; Minh, B. Q.; Jackson, C. J. A.
10.1101/2020.09.09.289108 — bioinformatics — Posted on 2020-09-28
308 Metabolomic Profiling and Mechanotransduction of Single Chondrocytes Encapsulated in Alginate Microgels
Fredrikson, J. P.; Brahmachary, P.; Archambault, Z.; Erdogan, E.; June, R. K.; Chang, C. B.
10.1101/2020.09.28.317008 — bioengineering — Posted on 2020-09-28
309 GHB confers neuroprotection by stabilizing the CaMKIIα hub domain
Leurs, U.; Klein, A. B.; McSpadden, E. D.; Griem-Krey, N.; Solbak, S. M.; Houlton, J.; Villumsen, I. S.; Vogensen, S. B.; Hamborg, L.; Gauger, S. J.; Palmelund, L. B.; Larsen, A. S. G.; Shehata, M. A.; Kelstrup, C. D.; Olsen, J. V.; Bach, A.; Burnie, R. O.; Kerr, D. S.; Gowing, E. K.; Teurlings, S. M. W.; Chi, C. C.; Gee, C. L.; Frolund, B.; Kornum, B. R.; van Woerden, G. M.; Clausen, R. P.; Kuriyan, J.; Clarkson, A. N.; Wellendorph, P.
10.1101/2020.09.28.310474 — biochemistry — Posted on 2020-09-28
310 ISRIB blunts the integrated stress response by allosterically antagonising the inhibitory effect of phosphorylated eIF2 on eIF2B
Zyryanova, A.; Kashiwagi, K.; Rato, C.; Harding, H. P.; Crespillo-Casado, A.; Perera, L.; Sakamoto, A.; Nishimoto, M.; Yonemochi, M.; Shirouzu, M.; Ito, T.; Ron, D.
10.1101/2020.09.28.316653 — biochemistry — Posted on 2020-09-28
311 A Maize Practical Haplotype Graph Leverages Diverse NAM Assemblies
Valdes Franco, J. A.; Gage, J. L.; Johnson, L. C.; Bradbury, P.; Miller, Z. R.; Buckler, E. S.; Romay, M. C.
10.1101/2020.08.31.268425 — genomics — Posted on 2020-09-28
314 FHL-1 interacts with human RPE cells through the α5β1 integrin and confers protection against oxidative stress
Choudhury, R.; Bayatti, N.; Scharff, R.; Szula, E.; Tilakaratna, V.; Udsen, M. S.; McHarg, S.; Askari, J.; Humphries, M.; Bishop, P. N.; Clark, S. J.
10.1101/2020.09.28.317263 — cell biology — Posted on 2020-09-28
316 O-GlcNAcylation, oxidation and CaMKII contribute to atrial fibrillation in type 1 and type 2 diabetes by distinct mechanisms
Mesubi, O. O.; Rokita, A. G.; Abrol, N.; Wu, Y.; Chen, B.; Wang, Q.; Granger, J. M.; Tucker-Bartley, A.; Luczak, E. D.; Murphy, K. R.; Umapathi, P.; Banerjee, P. S.; Boronina, T.; Cole, R. N.; Maier, L. S.; Wehrens, X. H.; Pomerantz, J. L.; Song, L.-S.; Ahima, R. S.; Hart, G. W.; Zachara, N. E.; Anderson, M. E.
10.1101/2020.02.18.954909 — molecular biology — Posted on 2020-09-28
317 Potential Rhodopsin and Bacteriochlorophyll-Based Dual Phototrophy in a High Arctic Glacier
Zeng, Y.; Chen, X.; Madsen, A. M.; Zervas, A.; Nielsen, T. K.; Andrei, A.-S.; Lund-Hansen, L. C.; Liu, Y.; Hansen, L. H.
10.1101/2020.09.28.316679 — microbiology — Posted on 2020-09-28
318 Biocontrol potential of grapevine endophytes against grapevine trunk pathogens
Silva-Valderrama, I.; Toapanta, D.; Miccono, M. d. l. A.; Diaz, G.; Lolas, M.; Cantu, D.; Castro, A.
10.1101/2020.09.28.312223 — microbiology — Posted on 2020-09-28
319 Phenolic acid-degrading Paraburkholderia prime decomposition in forest soil
Wilhelm, R. C.; DeRito, C. M.; Shapleigh, J. P.; Madsen, E. L.; Buckley, D. H.
10.1101/2020.09.28.317347 — microbiology — Posted on 2020-09-28
320 Colwellia and Marinobacter metapangenomes reveal species-specific responses to oil and dispersant exposure in deepsea microbial communities
Pena Montenegro, T. D.; Kleindienst, S.; Allen, A. E.; Eren, A. M.; McCrow, J.; Sanchez Calderon, J. D.; Arnold, J.; Joye, S. B.
10.1101/2020.09.28.317438 — microbiology — Posted on 2020-09-28
321 Genetically targeted reporter imaging of deep neuronal network in the mammalian brain
Shimojo, M.; Ono, M.; Takuwa, H.; Mimura, K.; Nagai, Y.; Fujinaga, M.; Kikuchi, T.; Okada, M.; Seki, C.; Tokunaga, M.; Maeda, J.; Takado, Y.; Takahashi, M.; Minamihisamatsu, T.; Zhang, M.-R.; Tomita, Y.; Suzuki, N.; Maximov, A.; Suhara, T.; Minamimoto, T.; Sahara, N.; Higuchi, M.
10.1101/2020.04.08.032870 — neuroscience — Posted on 2020-09-28
322 Multiple pathways of LRRK2-G2019S / Rab10 interaction in dopaminergic neurons
Fellgett, A.; Middleton, C. A.; Munns, J.; Ugbode, C.; Jaciuch, D.; Wilson, L.; Chawla, S.; Elliott, C.
10.1101/2020.09.28.316992 — neuroscience — Posted on 2020-09-28
324 Parietal cell-Specific SLC26A9 Deletion induces spontaneous Gastric Carcinogenesis in Mice
Liu, X.; Li, T.; Yuan, D.; Riederer, B.; Ma, Z.; Zhu, J.; Li, Y.; An, J.; Wen, G.; Jin, H.; Hu, C.; Zhang, M.; Yang, X.; Seidler, U.; Tuo, B.
10.1101/2020.09.28.316398 — cancer biology — Posted on 2020-09-28
326 Inferring intestinal mucosal immune cell associated microbiome species and microbiota-derived metabolites in inflammatory bowel disease
Narasimhan, R. L.; Throm, A. A.; Koshy, J. J.; Saldanha, K. M. R.; Chandranpillai, H.; Lal, R. D.; Kumravat, M.; Kumar K M, A.; Batra, A.; Zhong, F.; Liu, J.
10.1101/2020.09.18.304071 — bioinformatics — Posted on 2020-09-28
327 Intercellular signaling dynamics from a single cell atlas of the biomaterials response
Cherry, C.; Maestas, D. R.; Han, J.; Andorko, J. I.; Cahan, P.; Fertig, E. J.; Garmire, L. X.; Elisseeff, J. H.
10.1101/2020.07.24.218537 — bioengineering — Posted on 2020-09-28
328 Hyper-Truncated Glycans Augment the Activity of Neutrophil Granule Myeloperoxidase
Tjondro, H. C.; Ugonotti, J.; Kawahara, R.; Chatterjee, S.; Loke, I.; Chen, S.; Soltermann, F.; Hinneburg, H.; Parker, B. L.; Venkatakrishnan, V.; Dieckmann, R.; Grant, O. C.; Bylund, J.; Rodger, A.; Woods, R. J.; Karlsson-Bengtsson, A.; Struwe, W. B.; Thaysen-Andersen, M.
10.1101/2020.07.24.219956 — biochemistry — Posted on 2020-09-28
329 Host transcriptomic profiling of COVID-19 patients with mild, moderate, and severe clinical outcomes
Jain, R.; Ramaswamy, S.; Harilal, D.; Uddin, M.; Loney, T.; Nowotny, N.; Alsuwaidi, H.; Varghese, R.; Deesi, Z.; Alkhajeh, A.; Khansaheb, H.; Alsheikh-Ali, A.; Abou Tayoun, A.
10.1101/2020.09.28.316604 — genomics — Posted on 2020-09-28
330 Whole genome comparisons reveal panmixia among fall armyworm (Spodoptera frugiperda) from diverse locations
Schlum, K. A.; Lamour, K.; Placidi De Bortoli, C.; Banerjee, R.; Emrich, S. J.; Meagher, R.; Pereira, E.; Murua, M. G.; Sword, G. A.; Tessnow, A. E.; Dillon, D. V.; Linares Ramirez, A. M.; Akutse, K. S.; Schmidt-Jeffris, R.; Huang, F.; Reisig, D.; Jurat-Fuentes, J. L.
10.1101/2020.09.25.314005 — genomics — Posted on 2020-09-28
331 Frequent assembly of chimeric complexes in the protein interaction network of an interspecies yeast hybrid
Dandage, R.; Berger, C. M.; Gagnon-Arsenault, I.; Moon, K.-M.; Stacey, R. G.; Foster, L. J.; Landry, C. R.
10.1101/2020.06.02.130567 — evolutionary biology — Posted on 2020-09-28
334 Homeotic Regulation of Olfactory Receptor Choice via NFI-dependent Heterochromatic Silencing and Genomic Compartmentalization
Bashkirova, E.; Monahan, K.; Campbell, C. E.; Osinski, J. M.; Tan, L.; Schieren, I.; Barnea, G.; Xie, S.; Gronostajski, R. M.; Lomvardas, S.
10.1101/2020.08.30.274035 — developmental biology — Posted on 2020-09-28
336 Partial prion cross-seeding between fungal and mammalian amyloid signaling motifs
Bardin, T.; Daskalov, A.; Barrouilhet, S.; Granger-Farbos, A.; Salin, B.; Blancard, C.; Saupe, S. J.; Coustou, V.
10.1101/2020.07.22.215483 — microbiology — Posted on 2020-09-28
337 Accessory genome dynamics and structural variation of Shigella from persistent infections
Bengtsson, R. J.; Dallman, T. J.; Jenkins, C.; Allen, H.; Silva, M. D.; Stenhouse, G.; Pulford, C. V.; Bennett, R. J.; Baker, K. S.
10.1101/2020.09.28.316513 — microbiology — Posted on 2020-09-28
338 Spatial modulation of visual signals arises in cortex with active navigation
Diamanti, E. M.; Bai Reddy, C.; Schroeder, S.; Muzzu, T.; Harris, K. D.; Saleem, A. B.; Carandini, M.
10.1101/832915 — neuroscience — Posted on 2020-09-28
342 Post-Translational Modifications Soften Vimentin Intermediate Filaments
Kraxner, J.; Lorenz, C.; Menzel, J.; Parfentev, I.; Silbern, I.; Denz, M.; Urlaub, H.; Schwappach, B.; Koester, S.
10.1101/2020.06.05.135780 — biophysics — Posted on 2020-09-28
348 Discovery and Development of Human SARS-CoV-2 Neutralizing Antibodies using an Unbiased Phage Display Library Approach
Cao, X.; Maruyama, J.; Zhou, H.; Kerwin, L.; Sattler, R.; Manning, J. T.; Johnson, S.; Richards, S.; Blair, B.; Du, N.; Morais, K.; Lawrence, K.; Lu, L.; Pai, C.-I.; Li, D.; Brunswick, M.; Zhang, Y.; Ji, H.; Paessler, S.; Allen, R. D.
10.1101/2020.09.27.316174 — microbiology — Posted on 2020-09-28
349 Acute noise causes down-regulation of ECM protein expression in guinea pig cochlea
Shi, M.; Shi, L.; Ding, D.; Hu, Y.; Qi, G.; Zhan, L.; Zhu, Y.; Lv, P.; Yu, N.
10.1101/2020.09.27.315952 — immunology — Posted on 2020-09-28
351 The functional and phenotypic diversity of single T-cell infiltrates in human colorectal cancer as correlated with clinical outcome
Masuda, K.; Kornberg, A.; Lin, S.; Ho, P.; Secener, K.; Suek, N.; Bacarella, A. M.; Ingham, M.; Rosario, V.; Al-Masrou, A. M.; Lee-Kong, S. A.; Kiran, P. R.; Yan, K. S.; Stoeckius, M.; Smibert, P.; Oberstein, P. E.; Sims, P. A.; Han, A.
10.1101/2020.09.27.313445 — immunology — Posted on 2020-09-28
355 A Tethered Ligand Assay to Probe the SARS-CoV-2 ACE2 Interaction under Constant Force
Bauer, M. S.; Gruber, S.; Milles, L. F.; Nicolaus, T.; Schendel, L. C.; Gaub, H. E.; Lipfert, J.
10.1101/2020.09.27.315796 — biophysics — Posted on 2020-09-28
358 Defining a Global Map of Functional Group Based 3D Ligand-binding Motifs
Yang, L.; He, W.; Yun, Y.; Gao, Y.; Zhu, Z.; Teng, M.; Liang, Z.; Niu, L.
10.1101/2020.09.27.315762 — bioinformatics — Posted on 2020-09-28
364 Novel mechanisms of type IV pilus regulation in Acinetobacter baylyi
Ellison, C. K.; Dalia, T. N.; Shaevitz, J. W.; Gitai, Z.; Dalia, A. B.
10.1101/2020.09.28.317149 — microbiology — Posted on 2020-09-28
365 Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition
Greaney, A. J.; Starr, T. N.; Gilchuk, P.; Zost, S. J.; Binshtein, E.; Loes, A. N.; Hilton, S. K.; Huddleston, J.; Eguia, R.; Crawford, K. H.; Dingens, A. S.; Nargi, R. S.; Sutton, R. E.; Suryadevara, N.; Rothlauf, P. W.; Liu, Z.; Whelan, S. P.; Carnahan, R. H.; Crowe, J. E.; Bloom, J. D.
10.1101/2020.09.10.292078 — microbiology — Posted on 2020-09-28
367 Endosomal Sorting Drives the Formation of Mutant Prion Endoggresomes
Chassefeyre, R.; Chaiamarit, T.; Verhelle, A.; Weiser Novak, S.; Andrade, L. R.; Manor, U.; Encalada, S. E.
10.1101/2020.09.27.315846 — neuroscience — Posted on 2020-09-28
369 THAP1 Modulates Oligodendrocyte Maturationby Regulating ECM Degradation in Lysosomes
Yellajoshyula, D.; Pappas, S. S.; Rogers, A.; Choudhury, B.; Cookson, M.; Reed, X.; Shakkottai, V.; Giger, R.; Dauer, W. T.
10.1101/2020.09.27.316133 — neuroscience — Posted on 2020-09-28
371 Synthetic auxotrophy remains stable after continuous evolution and in co-culture with mammalian cells
Kunjapur, A. M.; Napolitano, M. G.; Hysolli, E.; Noguera, K.; Appleton, E. M.; Schubert, M. G.; Jones, M. A.; Iyer, S.; Mandell, D. J.; Church, G. M.
10.1101/2020.09.27.315804 — synthetic biology — Posted on 2020-09-28
373 Glutamic acid promotes hair growth in mice
Jara, C. P.; Berti, B. A.; Mendes, N. F.; Engel, D. F.; Zanesco, A. M.; Souza, G. F.; Velloso, L. A.; de Araujo, E. P.
10.1101/2020.09.27.315523 — pharmacology and toxicology — Posted on 2020-09-28
375 MicroED structure of the human adenosine receptor determined from a single nanocrystal in LCP
Martynowycz, M. W.; Shiriaeva, A.; Ge, X.; Hattne, J.; Nannenga, B. L.; Cherezov, V.; Gonen, T.
10.1101/2020.09.27.316109 — biophysics — Posted on 2020-09-28
380 Optimizing the molecular diagnosis of Covid-19 by combining RT-PCR and a pseudo-convolutional machine learning approach to characterize virus DNA sequences
Gomes, J. C.; Masood, A. I.; Silva, L. H. d. S.; Ferreira, J.; F. Junior, A. A.; Rocha, A. L. d. S.; Castro, L.; da Silva, N. R. C.; Fernandes, B. J. T.; dos Santos, W. P.
10.1101/2020.06.02.129775 — bioinformatics — Posted on 2020-09-28
383 Ultrafast Sample Placement on Existing Trees (UShER) Empowers Real-Time Phylogenetics for the SARS-CoV-2 Pandemic
Turakhia, Y.; Thornlow, B.; Hinrichs, A. S.; de Maio, N.; Gozashti, L.; Lanfear, R.; Haussler, D.; Corbett-Detig, R.
10.1101/2020.09.26.314971 — genomics — Posted on 2020-09-28
387 Residue-by-residue analysis of cotranslational membrane protein integration in vivo
Nicolaus, F.; Metola, A.; Mermans, D.; Liljenstrom, A.; Krc, A.; Abdullahi, S. M.; Zimmer, M.; Miller, T. F.; Von Heijne, G.
10.1101/2020.09.27.315283 — molecular biology — Posted on 2020-09-28
388 Identification of TMEM106B as proviral host factor for SARS-CoV-2
Baggen, J.; Persoons, L.; Jansen, S.; Vanstreels, E.; Jacquemyn, M.; Jochmans, D.; Neyts, J.; Dallmeier, K.; Maes, P.; Daelemans, D.
10.1101/2020.09.28.316281 — microbiology — Posted on 2020-09-28
389 Genome-Wide Asymptomatic B-Cell, CD4+ and CD8+ T-Cell Epitopes, that are Highly Conserved Between Human and Animal Coronaviruses, Identified from SARS-CoV-2 as Immune Targets for Pre-Emptive Pan-Coronavirus Vaccines
Prakash, S.; Ruchi, S.; Coulon, P.-G.; Dhanushkodi, N. R.; Chentoufi, A. A.; Tifrea, D. F.; Edwards, R. A.; Figueroa, C. J.; Schubl, S. D.; Hsieh, L.; Buchmeier, M. J.; Bouziane, M.; Nesburn, A. B.; Kuppermann, B. D.; BenMohamed, L.
10.1101/2020.09.27.316018 — immunology — Posted on 2020-09-28
390 Gut microbiome dysbiosis is associated with elevated toxic bile acids in Parkinson's disease
Li, P.; Killinger, B. A.; Beddows, I.; Ensink, E.; Yilmaz, A.; Lubben, N.; Lamp, J.; Schilthuis, M.; Vega, I. E.; Britschgi, M.; Pospisilik, A. J.; Brundin, P.; Brundin, L.; Graham, S.; Labrie, V.
10.1101/2020.09.26.279851 — neuroscience — Posted on 2020-09-28
394 SARS-CoV-2 structural coverage map reveals state changes that disrupt host immunity
O'Donoghue, S. I.; Schafferhans, A.; Sikta, N.; Stolte, C.; Kaur, S.; Ho, B.; Anderson, S.; Procter, J. B.; Dallago, C.; Bordin, N.; Adcock, M.; Rost, B.
10.1101/2020.07.16.207308 — bioinformatics — Posted on 2020-09-28
395 The COVID-19 PHARMACOME: Rational Selection of Drug Repurposing Candidates from Multimodal Knowledge Harmonization
Schultz, B. T.; Zaliani, A.; Ebeling, C.; Reinshagen, J.; Bojkova, D.; Lage-Rupprecht, V.; Karki, R.; Lukassen, S.; Gadiya, Y.; Ravindra, N. G.; Das, S.; Baksi, S.; Domingo-Fernandez, D.; Lentzen, M.; Strivens, M.; Raschka, T.; Cinatl, J.; DeLong, L. N.; Gribbon, P.; Geisslinger, G.; Ciesek, S.; van Dijk, D.; Gardner, S.; Tom Kodamullil, A.; Froehlich, H.; Peitsch, M.; Jacobs, M.; Hoeng, J.; Eils, R.; Claussen, C.; Hofmann-Apitius, M.
10.1101/2020.09.23.308239 — bioinformatics — Posted on 2020-09-28
401 Dynamically evolving novel overlapping gene as a factor in the SARS-CoV-2 pandemic
Nelson, C. W.; Ardern, Z.; Goldberg, T. L.; Meng, C.; Kuo, C.-H.; Ludwig, C.; Kolokotronis, S.-O.; Wei, X.
10.1101/2020.05.21.109280 — evolutionary biology — Posted on 2020-09-28
402 RUNX1 marks a luminal castration resistant lineage established at the onset of prostate development
Mevel, R.; Steiner, I.; Mason, S.; Galbraith, L. C. A.; Patel, R.; Fadlullah, M.; Ahmad, I.; Leung, H. Y.; Oliveira, P.; Blyth, K.; Baena, E.; Lacaud, G.
10.1101/2020.06.19.161604 — developmental biology — Posted on 2020-09-28
403 A semi-automated intestinal organoid screening method demonstrates epigenetic control of epithelial maturation
Ostrop, J.; Zwiggelaar, R.; Pedersen, M. T.; Gerbe, F.; Bösl, K.; Lindholm, H. T.; Diez-Sanchez, A.; Parmar, N.; Radetzki, S.; von Kries, J. P.; Jay, P.; Jensen, K. B.; Arrowsmith, C.; Oudhoff, M. J.
10.1101/2020.07.23.217414 — cell biology — Posted on 2020-09-28
404 Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19
Mirabelli, C.; Wotring, J. W.; Zhang, C. J.; McCarty, S. M.; Fursmidt, R.; Frum, T.; Kadambi, N. S.; Amin, A. T.; O'Meara, T. R.; Pretto-Kernahan, C. D.; Spence, J. R.; Huang, J.; Alysandratos, K. D.; Kotton, D. N.; Handelman, S. K.; Wobus, C. E.; Weatherwax, K. J.; Mashour, G. A.; O'Meara, M. J.; Sexton, J. Z.
10.1101/2020.05.27.117184 — cell biology — Posted on 2020-09-28
405 Emergence of Zika virus: Direct reversion of mutations and fitness restoration prior to spread to the Americas
Liu, J.; Liu, Y.; Shan, C.; Nunes, B. T. D.; Yun, R.; Haller, S. L.; Rafael, G. H.; Azar, S. R.; Andersen, C. R.; Plante, K. S.; Vasilakis, N.; Shi, P.-Y.; Weaver, S. C.
10.1101/2020.06.29.179150 — microbiology — Posted on 2020-09-28
406 A potent SARS-CoV-2 neutralizing human monoclonal antibody that reduces viral burden and disease severity in Syrian hamsters
Fagre, A.; Manhard, J.; Adams, R.; Eckley, M.; Zhan, S.; Lewis, J.; Rocha, S. M.; Woods, C.; Kuo, K.; Liao, W.; Li, L.; Corper, A.; Challa, D.; Mount, E.; Tumanut, C.; Tjalkens, R. B.; Aboelleil, T.; Fan, X.; Schountz, T.
10.1101/2020.09.25.313601 — microbiology — Posted on 2020-09-28
407 NeutrobodyPlex - Nanobodies to monitor a SARS-CoV-2 neutralizing immune response
Wagner, T. R.; Kaiser, P. D.; Gramlich, M.; Becker, M.; Traenkle, B.; Junker, D.; Haering, J.; Dulovic, A.; Schweizer, H.; Nueske, S.; Scholz, A.; Zeck, A.; Schenke-Layland, K.; Nelde, A.; Strengert, M.; Walz, J. S.; Ruetalo, N.; Schindler, M.; Schneiderhan-Marra, N.; Rothbauer, U.
10.1101/2020.09.22.308338 — immunology — Posted on 2020-09-28
410 Mediterranean Diet, Stress Resilience, and Aging in Nonhuman Primates
Shively, C. A.; Appt, S. E.; Chen, H.; Day, S. M.; Frye, B. M.; Shaltout, H. A.; Silverstein-Metzler, M. G.; Snyder-Mackler, N.; Uberseder, B.; Vitolins, M. Z.; Register, T. C.
10.1101/2020.09.25.313825 — physiology — Posted on 2020-09-28
412 Gazing into the Metaboverse: Automated exploration and contextualization of metabolic data
Berg, J. A.; Zhou, Y.; Waller, T. C.; Ouyang, Y.; Nowinski, S. M.; Van Ry, T.; George, I.; Cox, J. E.; Wang, B.; Rutter, J.
10.1101/2020.06.25.171850 — biochemistry — Posted on 2020-09-28
416 CircRNA may not be "circular"
Sun, H.; Wu, Z.; Liu, M.; Yu, L.; Li, J.; Ding, X.; Jin, H.
10.1101/2020.09.27.315275 — molecular biology — Posted on 2020-09-28
417 Enhanced tissue penetration of antibodies through pressurized immunohistochemistry
Fiorelli, R.; Sidhu, G. S.; Cebrian-Silla, A.; Luna Melendez, E.; Mehta, S.; Garcia-Verdugo, J. M.; Sanai, N.
10.1101/2020.09.25.311936 — molecular biology — Posted on 2020-09-28
419 A longitudinal study of white matter functional network in mild traumatic brain injury
Jia, X.; Chang, X.; Bai, L.; Wang, Y.; Dong, D.; Gan, S.; Wang, S.; Li, X.; Yang, X.; Sun, Y.; Li, T.; Xiong, F.; Niu, X.; Yan, H.
10.1101/2020.09.25.313338 — neuroscience — Posted on 2020-09-28
422 Impacted Spike Frequency Adaptation Associated with Reduction of KCNQ2/3 Promotes Seizure Activity in Temporal Lobe Epilepsy
Rong, L. R.; Cheng, J. S.; Shuo, T.; Bei, L.; Yang, L.; Lei, J.; Hong, N.; Yi, W. Q.; Di, Z. S.; Jing, G. R.
10.1101/2020.09.25.313254 — neuroscience — Posted on 2020-09-28
426 An optimal set of inhibitors for Reverse Engineering via Kinase Regularization.
Rata, S.; Gruver, J. S.; Trikoz, N.; Lukyanov, A.; Vultaggio, J.; Ceribelli, M.; Thomas, C.; Gujral, T. S.; Kirschner, M. W.; Peshkin, L.
10.1101/2020.09.26.312348 — systems biology — Posted on 2020-09-28
428 NDRG1 expression is an independent prognostic factor in inflammatory breast cancer
Schlee Villodre, E.; Gong, Y.; Huo, L.; Yoon, E. C.; Ueno, N. T.; Woodward, W. A.; Tripathy, D.; Song, J.; Debeb, B. G.
10.1101/2020.09.25.313817 — cancer biology — Posted on 2020-09-28
429 The Impact of Psychopathology, Social Adversity and Stress-relevant DNAm on Prospective Risk for Post-traumatic Stress: A Machine Learning Approach
Wani, A. H.; Aiello, A. E.; Kim, G. S.; Xue, F.; Martin, C. L.; Ratanatharathorn, A.; Qu, A.; Koenen, K.; Galea, S.; Wildman, D. E.; Uddin, M.
10.1101/2020.09.25.313635 — bioinformatics — Posted on 2020-09-28
433 TailTimer: an open-source device for automating the rodent tail immersion assay
Udell, M. E.; Garcia Martinez, A.; Wang, T.; Ni, J.; Hurt, C.; Mulligan, M. K.; Redei, E. E.; Chen, H.
10.1101/2020.09.25.313858 — animal behavior and cognition — Posted on 2020-09-28
437 Tissue topography steers migrating Drosophila border cells
Dai, W.; Guo, X.; Cao, Y. S.; Mondo, J. A.; Campanale, J. P.; Montell, B. J.; Burrous, H.; Streichan, S.; Gov, N.; Rappel, W.-J.; Montell, D.
10.1101/2020.09.27.316117 — developmental biology — Posted on 2020-09-28
438 Comparative Parallel Multi-Omics Analysis During the Induction of Pluripotent and Trophectoderm States
Buganim, Y.; Jaber, M.; Radwan, A.; Loyfer, N.; Abdeen, M.; Sebban, S.; Kolb, T.; Zapatka, M.; Makedonski, K.; Ernst, A.; Kaplan, T.
10.1101/2020.09.27.315259 — developmental biology — Posted on 2020-09-28
439 Lyl-1 marks and regulates primitive macrophages and microglia development
Wang, S.; Ren, D.; Kaushik, A.-L.; Matherat, G.; Lecluse, Y.; Filipp, D.; Vainchenker, W.; Raslova, H.; Plo, I.; Godin, I.
10.1101/2020.09.28.316570 — developmental biology — Posted on 2020-09-28
446 Both adaptive immunity and IL-1R1 dependent signals improve clearance of cytosolic virulent mycobacteria in vivo
van der Niet, S.; van Zon, M.; de Punder, K.; Grootemaat, A.; Rutten, S.; Moorlag, S.; Houben, D.; van der Sar, A.; Bitter, W.; Brosch, R.; Hernandez, R.; Pena, M. T.; Reits, E. E.; Mayer-Barber, K. D.; van der Wel, N.
10.1101/2020.09.27.315739 — cell biology — Posted on 2020-09-28
450 How a mouse licks a spout: Cortex-dependent corrections as the mouse tongue reaches for, and misses, targets
Bollu, T.; Ito, B. S.; Whitehead, S. C.; Kardon, B.; Redd, J.; Liu, M. H.; Goldberg, J. H.
10.1101/655852 — neuroscience — Posted on 2020-09-27
451 Highly replicated evolution of parapatric ecotypes
James, M. E.; Arenas-Castro, H.; Groh, J. S.; Engelstaedter, J.; Ortiz-Barrientos, D.
10.1101/2020.02.05.936401 — evolutionary biology — Posted on 2020-09-27
452 Evidence that non-pathogenic microorganisms drive sea star wasting disease through boundary layer oxygen diffusion limitation
Aquino, C. A.; Besemer, R. M.; DeRito, C. M.; Kocian, J.; Porter, I. R.; Raimondi, P.; Rede, J. E.; Schiebelhut, L. M.; Sparks, J. P.; Wares, J. P.; Hewson, I. H.
10.1101/2020.07.31.231365 — ecology — Posted on 2020-09-27
453 Salt tolerance QTL derived from the Bangladeshi landrace Horkuch
Haque, T.; Elias, S. M.; Razzaque, S.; Sudip Biswas, S.; Khan, S. F.; Jewel, N. A.; Rahman, S.; Juenger, T.; Seraj, Z. I.
10.1101/2020.03.01.971895 — plant biology — Posted on 2020-09-27
455 DIMT1, a regulator of ribosomal biogenesis, controls beta-cell protein synthesis, mitochondrial function and insulin secretion
Mulder, H.; Verma, G.; Bowen, A.; Hamilton, A.; Esguerra, J.; Karagiannopoulos, A.; Buscunan, R. C.; Lyons, C.; Cowan, E.; Fex, M.
10.1101/2020.09.27.313262 — molecular biology — Posted on 2020-09-27
456 The quantitative metabolome is shaped by abiotic constraints
Akbari, A.; Yurkovich, J. T.; Zielinski, D. C.; Palsson, B. O.
10.1101/2020.09.26.315135 — systems biology — Posted on 2020-09-27
457 Telomere length and TERT expression are associated with age in almond (Prunus dulcis)
D'Amico-Willman, K. M.; Anderson, E. S.; Gradziel, T. M.; Fresnedo Ramirez, J.
10.1101/2020.09.25.294074 — plant biology — Posted on 2020-09-27
458 Wood formation in an evergreen conifer is controlled by phloem transport of labile carbon, but nonstructural carbon concentrations are not
Rademacher, T.; Fonti, P.; LeMoine, J. M.; Fonti, M. V.; Basler, D.; Chen, Y.; Friend, A. D.; Seyednasrollah, B.; Eckes-Shephard, A. H.; Richardson, A. D.
10.1101/2020.09.25.313569 — plant biology — Posted on 2020-09-27
460 RaFAH: A superior method for virus-host prediction
Hernandes Coutinho, F.; Zaragosa-Solas, A.; Lopez-Perez, M.; Barylski, J.; Zielezinski, A.; Dutilh, B. E.; Edwards, R.; Rodriguez-Valera, F.
10.1101/2020.09.25.313155 — bioinformatics — Posted on 2020-09-27
461 Isoform-specific characterization implicates alternative splicing in APOBEC3B as a mechanism restricting APOBEC-mediated mutagenesis
Banday, A. R.; Onabajo, O. O.; Lin, S. H.-Y.; Vargas, J. M.; Obajemu, A.; Frankenberry, K.; Bayanjargal, A.; Lamy, P.; Czettelmeyer, C.; Florez-Vargas, O.; Pathak, V.; Dyrskjot Andersen, L.; Prokunina-Olsson, L.
10.1101/2020.09.27.315689 — genomics — Posted on 2020-09-27
463 Pleiotropic function of the oca2 gene underlies the evolution of sleep loss and albinism in cavefish
O'Gorman, M.; Thakur, S.; Imrie, G.; Moran, R.; Duboue, E. R.; Rohner, N.; McGaugh, S. E.; Keene, A. C.; Kowalko, J. E.
10.1101/2020.09.27.314278 — evolutionary biology — Posted on 2020-09-27
468 Immuno-Phenotyping of High-Grade Glioma Infiltrating Immune Cells Reveals Grade Specific Differences in Cells of Myeloid Origin
Ganesh, R. A.; Raghavan, J. V.; Sonpatki, P.; Naik, D.; Arunachalam, P.; Shah, D.; Lakshmikantha, A.; Pillai, S.; Chandrachari, K. P.; Mariswamappa, K.; D, S. L.; Shah, N.; Jhunjhunwala, S.
10.1101/2020.09.26.314542 — immunology — Posted on 2020-09-27
470 Topological Features of Electroencephalography are Reference-Invariant
Billings, J.; Tivadar, R.; Murray, M. M.; Franceschiello, B.; Petri, G.
10.1101/2020.09.25.311829 — neuroscience — Posted on 2020-09-27
472 Applying SCA for high-accuracy cortical auditory ERPs in children
Bruzzone, S. E. P.; Haumann, N. T.; Kliuchko, M.; Vuust, P.; Brattico, E.
10.1101/2020.09.25.313809 — neuroscience — Posted on 2020-09-27
473 Measuring functional connectivity with wearable MEG
Boto, E.; Hill, R. M.; Rea, M.; Holmes, N.; Seedat, Z. A.; Leggett, J.; Shah, V.; Osborne, J.; Bowtell, R.; Brookes, M. J.
10.1101/2020.09.25.313502 — neuroscience — Posted on 2020-09-27
474 Plant Prionome maps reveal specific roles of prion-like proteins in stress and memory
Garai, S.; Gulia, C.; Pandey, J.; Singla-Pareek, S. L.; Sopory, S. K.; Kaur, C.; Yadav, G.
10.1101/2020.09.25.311993 — plant biology — Posted on 2020-09-27
481 CARMIL3 is important for cell migration and morphogenesis during early development in zebrafish
Stark, B. C.; Gao, Y.; Belk, L.; Culver, M. A.; Hu, B.; Sepich, D. S.; Mekel, M.; Solnica-Krezel, L.; Lin, F.; Cooper, J.
10.1101/2020.09.27.315655 — developmental biology — Posted on 2020-09-27
483 Longitudinal multi-omics along gingivitis development reveal a suboptimal-health gum state with periodontitis-like microbiome
Huang, S.; He, T.; Yue, F.; Xu, V.; Wang, S.; Zhu, P.; Teng, F.; Sun, Z.; Liu, X.; Jing, G.; Su, X.; Jin, L.; Liu, J.; Xu, J.
10.1101/2020.09.26.315127 — microbiology — Posted on 2020-09-27
484 Organization of Peptidoglycan Synthesis in Nodes and Separate Rings at Different Stages of Cell Division of Streptococcus pneumoniae
Perez, A. J.; Boersma, M. J.; Bruce, K. E.; Lamanna, M. M.; Shaw, S. L.; Tsui, H.-C. T.; Taguchi, A.; Carlson, E. E.; VanNieuwenhze, M. S.; Winkler, M. E.
10.1101/2020.09.27.315481 — microbiology — Posted on 2020-09-27
485 Prevailing role of mucosal immunoglobulins and B cells in teleost skin immune responses to bacterial infection
Zhang, X.; Yu, Y.; Xu, H.; Huang, Z.; Liu, X.; Cao, J.; Meng, K.; Wu, Z.; Han, G.; Zhan, M.; Ding, L.; Kong, W.; Li, N.; Takizawa, F.; Sunyer, O.; xu, z.
10.1101/2020.09.21.305920 — immunology — Posted on 2020-09-27
486 Genetic variation in CSMD1 affects amygdala connectivity and prosocial behavior
Bickart, K. C.; Napolioni, V.; Khan, R. R.; Kim, Y.; Altmann, A.; Richiardi, J.; Newsom, M.; Sadaghiani, S.; Banaschewski, T.; Bokde, A. L.; Quinlan, E. B.; Desrivieres, S.; Flor, H.; Garavan, H.; Gowland, P.; Heinz, A.; Ittermann, B.; Martinot, J.-L.; Paillere Martinot, M.-L.; Artiges, E.; Nees, F.; Papadopoulos Orfanos, D.; Paus, T.; Poustka, L.; Froehner, J. H.; Smolka, M. N.; Walter, H.; Whelan, R.; Schumann, G.; Ng, B.; Greicius, M. D.; Consortium, I.
10.1101/2020.09.27.315622 — neuroscience — Posted on 2020-09-27
487 The bacterial membrane fission protein FisB requires homo-oligomerization and lipid-binding to catalyze membrane scission
Landajuela, A.; Braun, M.; Rodrigues, C. D. A.; Doan, T.; Horenkamp, F. A.; Andronicos, A.; Shteyn, V.; Williams, N. D.; Lin, C.; Rudner, D. Z.; Karatekin, E.
10.1101/2020.09.25.313023 — biophysics — Posted on 2020-09-27
489 Defining the Syrian hamster as a highly susceptible preclinical model for SARS-CoV-2 infection
Rosenke, K.; Meade-White, K.; Letko, M. C.; Clancy, C.; Hansens, F.; Liu, Y.; Okumura, A.; Tang-Huau, T.-L.; Li, R.; Saturday, G.; Feldmann, F.; Scott, D.; Wang, Z.; Munster, V.; Jarvis, M.; Feldmann, H.
10.1101/2020.09.25.314070 — microbiology — Posted on 2020-09-27
490 Predictive Maps in Rats and Humans for Spatial Navigation
de Cothi, W.; Nyberg, N.; Griesbauer, E.-M.; Ghaname, C.; Zisch, F.; Fletcher, L.; Newton, C.; Renaudineau, S.; Bendor, D.; Grieves, R.; Duvelle, E.; Barry, C.; Spiers, H. J.
10.1101/2020.09.26.314815 — animal behavior and cognition — Posted on 2020-09-27
493 Brain-wide single neuron reconstruction reveals morphological diversity in molecularly defined striatal, thalamic, cortical and claustral neuron types
Peng, H.; Xie, P.; Liu, L.; Kuang, X.; Wang, Y.; Qu, L.; Gong, H.; Jiang, S.; Li, A.; Ruan, Z.; Ding, L.; Chen, C.; Chen, M.; Daigle, T. L.; Ding, Z.; Duan, Y.; Feiner, A.; He, P.; Hill, C.; Hirokawa, K. E.; Hong, G.; Huang, L.; Kedebe, S.; Kuo, H.-C.; Larsen, R.; Lesnar, P.; Li, L.; Li, Q.; Li, X.; Li, Y.; Li, Y.; Liu, A.; Lu, D.; Mok, S.; Ng, L.; Nguyen, T. N.; Ouyang, Q.; Pan, J.; Shen, E.; Song, Y.; Sunkin, S. M.; Tasic, B.; Veldman, M. B.; Wakeman, W.; Wan, W.; Wang, P.; Wang, Q.; Wang, T.; Wang, Y.; Xiong, F.; Xiong, W.; Xu, W.; Yao, Z.; Ye, M.; Yin, L.; Yu, Y.; Yuan, J.; Yuan, J.; Yun,
10.1101/675280 — neuroscience — Posted on 2020-09-27
495 Sex-specific lesion topographies explain outcomesafter acute ischemic stroke
Bonkhoff, A. K.; Schirmer, M. D.; Bretzner, M.; Hong, S.; Regenhardt, R.; Brudfors, M.; Donahue, K.; Nardin, M.; Dalca, A.; Giese, A.-K.; Etherton, M.; Hancock, B.; Mocking, S.; McIntosh, E.; Attia, J.; Benavente, O.; Bevan, S.; Cole, J.; Donatti, A.; Griessenauer, C.; Heitsch, L.; Holmegaard, L.; Jood, K.; Jimenez-Conde, J.; Kittner, S.; Lemmens, R.; Levi, C.; McDonough, C.; Meschia, J.; Phuah, C.-L.; Rolfs, A.; Ropele, S.; Rosand, J.; Roquer, J.; Rundek, T.; Sacco, R.; Schmidt, R.; Sharma, P.; Slowik, A.; Soderholm, M.; Sousa, A.; Stanne, T.; Strbian, D.; Tatlisumak, T.; Thijs, V.; Vagal, A.
10.1101/2020.09.25.308742 — neuroscience — Posted on 2020-09-27
496 Predictive Maps in Rats and Humans for Spatial Navigation
de Cothi, W.; Nyberg, N.; Griesbauer, E.-M.; Ghaname, C.; Zisch, F.; Fletcher, L.; Newton, C.; Renaudineau, S.; Bendor, D.; Grieves, R.; Duvelle, E.; Barry, C.; Spiers, H. J.
10.1101/2020.09.26.314815 — animal behavior and cognition — Posted on 2020-09-27
497 Mechanosensitive Ion Channel Piezo1 Regulates Myocyte Fusion during Skeletal Myogenesis
Ortuste Quiroga, H. P.; Yokoyama, S.; Ganassi, M.; Nakamura, K.; Yamashita, T.; Raimbach, D.; Hagiwara, A.; Asakura, A.; Suzuki, Y.; Tominaga, M.; Zammit, P. S.; Goto, K.
10.1101/2020.09.27.315242 — molecular biology — Posted on 2020-09-27
499 Brain-wide single neuron reconstruction reveals morphological diversity in molecularly defined striatal, thalamic, cortical and claustral neuron types
Peng, H.; Xie, P.; Liu, L.; Kuang, X.; Wang, Y.; Qu, L.; Gong, H.; Jiang, S.; Li, A.; Ruan, Z.; Ding, L.; Chen, C.; Chen, M.; Daigle, T. L.; Ding, Z.; Duan, Y.; Feiner, A.; He, P.; Hill, C.; Hirokawa, K. E.; Hong, G.; Huang, L.; Kedebe, S.; Kuo, H.-C.; Larsen, R.; Lesnar, P.; Li, L.; Li, Q.; Li, X.; Li, Y.; Li, Y.; Liu, A.; Lu, D.; Mok, S.; Ng, L.; Nguyen, T. N.; Ouyang, Q.; Pan, J.; Shen, E.; Song, Y.; Sunkin, S. M.; Tasic, B.; Veldman, M. B.; Wakeman, W.; Wan, W.; Wang, P.; Wang, Q.; Wang, T.; Wang, Y.; Xiong, F.; Xiong, W.; Xu, W.; Yao, Z.; Ye, M.; Yin, L.; Yu, Y.; Yuan, J.; Yuan, J.; Yun,
10.1101/675280 — neuroscience — Posted on 2020-09-27
500 Microbial function and genital inflammation in young South African women at high risk of HIV infection
Alisoltani, A.; Manhanzva, M. T.; Potgieter, M. G.; Balle, C.; Bell, L.; Ross, E.; Iranzadeh, A.; du Plessis, M.; Radzey, N.; McDonald, Z.; Calder, B.; Allali, I.; Mulder, N.; Dabee, S.; Barnabas, S.; Gamieldien, H.; Godzik, A.; Blackburn, J. M.; Tabb, D. L.; Bekker, L.-G.; Jaspan, H. B.; Passmore, J.-A. S.; Masson, L.
10.1101/2020.03.10.986646 — microbiology — Posted on 2020-09-27
504 Bimolecule detection for Extracellular Vesicle Screening
Kaneda, H.; Ida, Y.; Kuwahara, R.; Sato, I.; Nakano, T.; Tokuda, H.; Sato, T.; Murakoshi, T.; Honke, K.; Kotani, N.
10.1101/2020.07.23.217018 — biochemistry — Posted on 2020-09-27
505 Bleaching resistant corals retain heat tolerance following acclimatization to environmentally distinct reefs
Barott, K. L.; Huffmyer, A. S.; Davidson, J. M.; Lenz, E. A.; Matsuda, S. B.; Hancock, J. R.; Innis, T.; Drury, C.; Putnam, H. M.; Gates, R. D.
10.1101/2020.09.25.314203 — ecology — Posted on 2020-09-26
509 Prenatal Methadone Exposure Disrupts Behavioral Development and Alters Motor Neuron Intrinsic Properties and Local Circuitry
Grecco, G. G.; Mork, B.; Huang, J.-Y.; Metzger, C. E.; Haggerty, D. L.; Reeves, K. C.; Gao, Y.; Hoffman, H.; Katner, S. N.; Masters, A. R.; Morris, C. W.; Newell, E. A.; Engleman, E. A.; Baucum, A. J.; Kim, J.; Yamamoto, B. K.; Allen, M. R.; Wu, Y.-C.; Lu, H.-C.; Sheets, P. L.; Atwood, B. K.
10.1101/2020.09.25.314013 — neuroscience — Posted on 2020-09-26
510 Peripheral Taenia infection increases immunoglobulins in the central nervous system.
Van Belle, S. C.; de Lange, A.; Tomes, H.; Lucas, R.; Naidoo, V.; Raimondo, J. V.
10.1101/2020.09.26.314567 — neuroscience — Posted on 2020-09-26
511 Association between COMT gene Val158Met heterozygote polymorphism and enhanced brain predicting processes
Bonetti, L.; Sedghi, N. A.; Bruzzone, S. E. P.; Haumann, N. T.; Paunio, T.; Kantojarvi, K.; Kliuchko, M.; Vuust, P.; Brattico, E.
10.1101/2020.09.26.314732 — neuroscience — Posted on 2020-09-26
512 Population Level Variation of Transposable Elements in a Maize Diversity Panel
O'Connor, C.; Qiu, Y.; Della Coletta, R.; Monnahan, P.; Noshay, J. M.; Gilbert, A.; Anderson, S. N.; McGaugh, S. E.; Springer, N. M.; Hirsch, C.
10.1101/2020.09.25.314401 — plant biology — Posted on 2020-09-26
516 The vitamin A ester retinyl propionate has a unique metabolic profile and higher retinoid-related bioactivity over retinol and retinyl palmitate in human skin models.
Bjerke, D.; Li, R.; Price, J. M.; Dobson, R.; Rodrigues, M.; Tey, C.; Vires, L.; Adams, R. L.; Sherrill, J. D.; Styczynski, P. B.; Goncalves, K.; Maltman, V.; Przyborski, S.; Oblong, J.
10.1101/2020.09.26.315036 — biochemistry — Posted on 2020-09-26
517 Genotypic similarity among algal symbionts corresponds to associations with closely related coral hosts
Reich, H. G.; Kitchen, S. A.; Stankiewicz, K. H.; Devlin-Durante, M.; Fogarty, N. D.; Baums, I. B.
10.1101/2020.09.26.314773 — genomics — Posted on 2020-09-26
518 Evolution of the canonical sex chromosomes of the guppy and its relatives
Kirkpatrick, M.; Dixon, G.; Sardell, J. M.; Schartl, M.; Peichel, C.
10.1101/2020.09.25.314112 — genomics — Posted on 2020-09-26
521 Effects of species traits and ecosystem characteristics on species detection by eDNA metabarcoding in lake fish communities
Doi, H.; Matsuoka, S.; Matsuzaki, S.-i. S.; Nagano, M.; Sato, H.; Yamanaka, H.; Matsuhashi, S.; Yamamoto, S.; Minamoto, T.; Araki, H.; Ikeda, K.; Kato, A.; Kumei, K.; Maki, N.; Mitsuzuka, T.; Takaraha, T.; Toki, K.; Ueda, N.; Watanabe, T.; Yamazoe, K.; Miya, M.
10.1101/2020.09.25.314336 — ecology — Posted on 2020-09-26
524 Discovery of a new Neisseria gonorrhoeae Type IV pilus assembly factor, TfpC
Hu, L. I.; Yin, S.; Ozer, E. A.; Sewell, L.; Rehman, S.; Garnett, J.; SEIFERT, H. S.
10.1101/2020.09.26.314724 — microbiology — Posted on 2020-09-26
525 MogR is a ubiquitous transcriptional repressor affecting motility, biofilm formation and virulence in the Bacillus cereus group
Smith, V.; Josefsen, M.; Lindbäck, T.; Hegna, I. K.; Finke, S.; Tourasse, N. J.; Nielsen-LeRoux, C.; Okstad, O. A.; Fagerlund, A.
10.1101/2020.09.26.311894 — microbiology — Posted on 2020-09-26
527 Localization and Functional Characterization of the Alternative Oxidase in Naegleria
Cantoni, D.; Osborne, A. O.; Taib, N.; Thompson, G.; Kazana, E.; Edrich, E.; Brown, I. R.; Gribaldo, S.; Gourlay, C.; Tsaousis, A.
10.1101/2020.09.26.314807 — microbiology — Posted on 2020-09-26
528 Species-specific assembly of root-associated bacterial microbiota mediated by a combination of plant specialized metabolites
Shimasaki, T.; Masuda, S.; Garrido-Oter, R.; Kawasaki, T.; Aoki, Y.; Shibata, A.; Suda, W.; Shirasu, K.; Yazaki, K.; Nakano, R. T.; Sugiyama, A.
10.1101/2020.09.25.313031 — microbiology — Posted on 2020-09-26
529 The SPPL3-defined glycosphingolipid repertoire regulates immune responses by improving HLA class I access
Jongsma, M. L. M.; Raaben, M.; de Waard, A. A.; Zhang, T.; Cabukusta, B.; Platzer, R.; Blomen, V. A.; Xagara, A.; Verkerk, T.; Bliss, S.; Janssen, L.; Stickel, E.; Holst, S.; Plomp, R.; Mulder, A.; Ferrone, S.; Claas, F. H. J.; Heemskerk, M. H. M.; Griffioen, M.; Overkleeft, H.; Huppa, J. B.; Wuhrer, M.; Brummelkamp, T. R.; Neefjes, J.; Spaapen, R. M.
10.1101/2020.09.26.313585 — immunology — Posted on 2020-09-26
530 Intrarenal B cells integrate in situ innate and adaptive immunity in human renal allograft rejection
Asano, Y.; Daccache, J.; Jain, D.; Ko, K.; Kinloch, A.; Veselits, M.; Wolfgeher, D.; Chang, A.; Josephson, M.; Cunningham, P.; Tambur, A.; Khan, A.; Pillai, S.; Chong, A. S.; Clark, M. R.
10.1101/2020.09.26.314377 — immunology — Posted on 2020-09-26
534 Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies
Lukow, D. A.; Sausville, E. L.; Suri, P.; Chunduri, N. K.; Leu, J.; Kendall, J.; Wang, Z.; Storchova, Z.; Sheltzer, J. M.
10.1101/2020.09.25.314229 — cancer biology — Posted on 2020-09-26
535 Aneuploidy-driven genome instability triggers resistance to chemotherapy
Ippolito, M. R.; Martis, V.; Hong, C.; Wardenaar, R.; Zerbib, J.; Spierings, D. C. J.; Ben-David, U.; Foijer, F.; Santaguida, S.
10.1101/2020.09.25.313924 — cancer biology — Posted on 2020-09-26
538 Droplet microfluidic sequencing of HIV genomes and integration sites
Sun, C.; Liu, L.; Perez, L.; Li, X.; Liu, Y.; Xu, P.; Boritz, E. A.; Mullins, J. I.; Abate, A.
10.1101/2020.09.25.314120 — genomics — Posted on 2020-09-26
539 Whole genome comparisons reveal panmixia among fall armyworm (Spodoptera frugiperda) from diverse locations
Schlum, K. A.; Lamour, K.; Placidi De Bortoli, C.; Banerjee, R.; Emrich, S. J.; Meagher, R.; Pereira, E.; Murua, M. G.; Sword, G. A.; Tessnow, A. E.; Dillon, D. V.; Linares Ramirez, A. M.; Akutse, K. S.; Schmidt-Jeffris, R.; Huang, F.; Reisig, D.; Jurat-Fuentes, J. L.
10.1101/2020.09.25.314005 — genomics — Posted on 2020-09-26
541 Genomics of an avian neo-sex chromosome reveals the evolutionary dynamics of recombination suppression and sex-linked genes
Sigeman, H.; Strandh, M.; Proux-Wera, E.; Kutschera, V. E.; Ponnikas, S.; Zhang, H.; Lundberg, M.; Soler, L.; Bunikis, I.; Tarka, M.; Hasselquist, D.; Nystedt, B.; Westerdahl, H.; Hansson, B.
10.1101/2020.09.25.314088 — evolutionary biology — Posted on 2020-09-26
545 Glioma stem cells invasive phenotype at optimal stiffness is driven by MGAT5 dependent mechanosensing.
Marhuenda, E.; Fabre, C.; Zhang, C.; Martin-Fernandez, M.; Iskratsch, T.; Saleh, A.; Bauchet, L.; Cambedouzou, J.; Hugnot, J.-P.; Duffau, H.; Dennis, J.; Cornu, D.; Bakalara, N.
10.1101/2020.09.25.313783 — cell biology — Posted on 2020-09-26
546 GAMYB modulates bHLH142 and is homeostatically regulated by TDR during rice anther tapetal and pollen development
Ko, S.-S.; Li, M.-J.; Ho, Y.-C.; Yu, C.-P.; Yang, T.-T.; Lin, Y.-J.; Hsing, H.-C.; Chen, T.-K.; Jhong, C.-M.; Li, W.-H.; Ku, M. S.-B.
10.1101/2020.09.26.314641 — molecular biology — Posted on 2020-09-26
547 Social Stress Alters Immune Response and Results in Higher Viral Load During Acute SIV Infection in a Pigtailed Macaque Model of HIV
Guerrero-Martin, S. M.; Rubin, L. H.; Mcgee, K. M.; Shirk, E. N.; Queen, S. E.; Li, M.; Bullock, B.; Carlson, B. W.; Adams, R. J.; Gama, L.; Graham, D.; Zink, C.; Clements, J. E.; Mankowski, J. L.; Metcalf Pate, K. A.
10.1101/2020.04.21.054130 — microbiology — Posted on 2020-09-26
549 Temporal patterns in Ixodes ricinus microbial communities: an insight into tick-borne microbe interactions
LEJAL, E.; Chiquet, J.; Aubert, J.; Robin, S.; Estrada Pena, A.; Rue, O.; Midoux, C.; Mariadassou, M.; Bailly, X.; Cougoul, A.; Gasqui, P.; Cosson, J.-F.; Chalvet-Montfray, K.; Vayssier-Taussat, M.; Pollet, T.
10.1101/2020.09.26.314179 — microbiology — Posted on 2020-09-26
551 Environmental drivers of plankton protist communities along latitudinal and vertical gradients in the oldest and deepest freshwater lake
David, G. M.; Moreira, D.; Reboul, G.; Annenkova, N.; Galindo, L. J.; Bertolino, P.; Lopez-Archilla, A. I.; Jardillier, L.; Lopez-Garcia, P.
10.1101/2020.09.26.308536 — microbiology — Posted on 2020-09-26
552 A high affinity human monoclonal antibody against Pfs230 binds multiple parasite stages and blocks oocyst formation in mosquitoes
Coelho, C. H.; Tang, W. K.; Burkhardt, M.; Galson, J. D.; Muratova, O.; Salinas, N.; Alves e Silva, T. L.; Reiter, K.; MacDonald, N.; Nguyen, V.; Byrne-Steele, M.; Pan, W.; Hou, X.; Brown, B.; Eisenhower, M.; Han, J.; Jenkins, B.; Doritchamou, J. Y. A.; Smelkinson, M.; Vega-Rodriguez, J.; Truck, J.; Taylor, J. J.; Sagara, I.; Renn, J.; Tolia, N.; Duffy, P.
10.1101/2020.09.25.313478 — immunology — Posted on 2020-09-26
554 Genome-wide analyses point to differences in genetic architecture of BMI between tall and short people
Lin, B.; Mullin, B. H.; Wilson, S. G.; Walsh, J. P.; Li, Y.; Adan, R. H.; Lukyx, J. J.
10.1101/2020.09.24.312181 — genetics — Posted on 2020-09-26
556 High-throughput whole-brain mapping of rhesus monkey at micron resolution
Xu, F.; Shen, Y.; Ding, L.; Yang, C.-Y.; Tan, H.; Wang, H.; Zhu, Q.; Xu, R.; Wu, F.; Xu, C.; Li, Q.; Su, P.; Zhang, L. I.; Dong, H.; Desimone, R.; Xu, F.; Hu, X.; Lau, P.-M.; Bi, G.-Q.
10.1101/2020.09.25.313395 — neuroscience — Posted on 2020-09-26
558 Diet, psychosocial stress, and Alzheimer's disease-related neuroanatomy in female nonhuman primates
Frye, B. M.; Craft, S.; Register, T. C.; Andrews, R. N.; Appt, S. E.; Vitolins, M. Z.; Uberseder, B.; Silverstein-Metzler, M. G.; Chen, H.; Whitlow, C. T.; Kim, J.; Barcus, R. A.; Lockhart, S. N.; Hoscheidt, S.; Say, B. M.; Corbitt, S. E.; Shively, C. A.
10.1101/2020.09.25.313593 — neuroscience — Posted on 2020-09-26
559 Initial experience has lasting effect on repeated risky decisions
Kobor, A.; Kardos, Z.; Takacs, A.; Elteto, N.; Janacsek, K.; Toth-Faber, E.; Csepe, V.; Nemeth, D.
10.1101/2020.09.25.313551 — neuroscience — Posted on 2020-09-26
560 Treating Porcine Abscesses With Histotripsy: A Pilot Study
Matula, T.; Wang, Y.-N.; Khokhlova, T.; Leotta, D.; Kucewicz, J.; Brayman, A.; Bruce, M.; Maxwell, A.; MacConaghy, B.; Thomas, G.; Chernikov, V.; Buravkov, S.; Khokhlova, V.; Richmond, K.; Chan, K.; Monsky, W.
10.1101/2020.09.25.314302 — bioengineering — Posted on 2020-09-26
562 Human papillomavirus 16 E2 repression of TWIST1 transcription is a potential mediator of HPV16 cancer outcomes
Fontan, C. T.; Das, D.; Bristol, M. L.; James, C. D.; Wang, X.; Lohner, H.; Atfi, A.; Morgan, I. M.
10.1101/2020.09.25.314484 — cancer biology — Posted on 2020-09-26
563 Apoptosis in plants: from semantic appeal to empirical rejection
Minina, E. A.; Dauphinee, A. N.; Ballhaus, F.; Gogvadze, V.; Smertenko, A. P.; Bozhkov, P. V.
10.1101/2020.09.26.314583 — plant biology — Posted on 2020-09-26
565 Requirements for FisB-mediated membrane fission during sporulation
Landajuela, A.; Braun, M.; Rodrigues, C. D. A.; Doan, T.; Horenkamp, F. A.; Andronicos, A.; Shteyn, V.; Williams, N. D.; Lin, C.; Rudner, D. Z.; Karatekin, E.
10.1101/2020.09.25.313023 — biophysics — Posted on 2020-09-26
566 Single-molecule light-sheet microscopy with local nanopipette delivery
Li, B.; Ponjavic, A.; Chen, W.-H.; Hopkins, L.; Hughes, C.; Ye, Y.; Bryant, C. E.; Klenerman, D.
10.1101/2020.09.25.313973 — biophysics — Posted on 2020-09-26
568 Mg2+-binding shifts the IM30 activity from membrane protection to membrane destabilization
Junglas, B.; Axt, A.; Siebenaller, C.; Sonel, H.; Hellmann, N.; Weber, S. A. L.; Schneider, D.
10.1101/2020.09.25.313916 — biochemistry — Posted on 2020-09-26
569 A multiscale analysis of early flower development in Arabidopsis provides an integrated view of molecular regulation and growth control
Refahi, Y.; Zardilis, A.; Michelin, G.; Wightman, R.; Leggio, B.; Legrand, J.; Faure, E.; Vachez, L.; Armezzani, A.; Zhao, F.; Das, P.; Prunet, N.; Meyerowitz, E. M.; Godin, C.; Malandain, G.; Jonsson, H.; Traas, J.
10.1101/2020.09.25.313312 — developmental biology — Posted on 2020-09-26
570 The extracellular matrix protein agrin is essential for epicardial epithelial-to-mesenchymal transition during heart development
Sun, X.; Malandraki-Miller, S.; Kennedy, T.; Bassat, E.; Klaourakis, K.; Zhou, J.; Gamen, E.; Vieira, J. M.; Tzahor, E.; Riley, P.
10.1101/2020.09.25.313742 — developmental biology — Posted on 2020-09-26
571 Runx1 Shapes the Chromatin Landscape Via a Cascade of Direct and Indirect Targets
Hass, M. R.; Brissette, D.; Parameswaran, S.; Pujato, M.; Donmez, O.; Kottyan, L. C.; Weirauch, M. T.; Kopan, R.
10.1101/2020.09.25.313767 — genomics — Posted on 2020-09-26
573 A high affinity human monoclonal antibody against Pfs230 binds multiple parasite stages and blocks oocyst formation in mosquitoes
Coelho, C. H.; Tang, W. K.; Burkhardt, M.; Galson, J. D.; Muratova, O.; Salinas, N.; Alves e Silva, T. L.; Reiter, K.; MacDonald, N.; Nguyen, V.; Byrne-Steele, M.; Pan, W.; Hou, X.; Brown, B.; Eisenhower, M.; Han, J.; Jenkins, B.; Doritchamou, J. Y. A.; Smelkinson, M.; Vega-Rodriguez, J.; Truck, J.; Sagara, I.; Renn, J.; Tolia, N.; Duffy, P.
10.1101/2020.09.25.313478 — immunology — Posted on 2020-09-26
574 Expansion Revealing: Decrowding Proteins to Unmask Invisible Brain Nanostructures
Sarkar, D.; Kang, J.; Wassie, A. T.; Schroeder, M. E.; Peng, Z.; Tarr, T. B.; Tang, A.-H.; Niederst, E.; Young, J. Z.; Tsai, L.-H.; Blanpied, T. A.; Boyden, E. S.
10.1101/2020.08.29.273540 — bioengineering — Posted on 2020-09-26
575 Chitin Biosynthesis Genes in Diaphorina citri
Miller, S.; Tamayo, B.; Shippy, T.; Hosmani, P. S.; Flores-Gonzalez, M.; Mueller, L. A.; Hunter, W. B.; D'elia, T.; Brown, S. J.; Saha, S.
10.1101/2020.09.22.309211 — genomics — Posted on 2020-09-26
576 Rbm10 facilitates heterochromatin assembly via the Clr6 HDAC complex
Weigt, M.; Gao, Q.; Ban, H.; He, H.; Mastrobuoni, G.; Kempa, S.; Chen, W.; Li, F.
10.1101/518936 — molecular biology — Posted on 2020-09-26
577 TThe stability and ABA import activity of NRT1.2 are partially regulated by CEPR2 in Arabidopsis
Yu, Z.; Zhang, L.; Xu, Y.; Yu, M.; Zhang, S.; Yang, G.; Huang, J.; Yan, K.; Zheng, C.; Wu, C.
10.1101/2020.02.18.953711 — molecular biology — Posted on 2020-09-26
579 Local circuit allowing hypothalamic control of hippocampal area CA2 activity and consequences for CA1
Robert, V.; Therreau, L.; Huang, A. J. Y.; Boehringer, R.; Polygalov, D.; McHugh, T. J.; Chevaleyre, V.; Piskorowski, R. A.
10.1101/2020.09.18.303693 — neuroscience — Posted on 2020-09-26
581 Exhaustive identification of conserved upstream open reading frames with potential translational regulatory functions from animal genomes
Takahashi, H.; Miyaki, S.; Onouchi, H.; Motomura, T.; Idesako, N.; Takahashi, A.; Murase, M.; Fukuyoshi, S.; Endo, T.; Satou, K.; Naito, S.; Itoh, M.
10.1101/672840 — bioinformatics — Posted on 2020-09-26
585 DDX3 depletion represses translation of mRNAs with complex 5' UTRs
Calviello, L.; Venkataramanan, S.; Rogowski, K. J.; Wyler, E.; Wilkins, K.; Tejura, M.; Thai, B.; Krol, J.; Filipowicz, W.; Landthaler, M.; Floor, S. N.
10.1101/589218 — molecular biology — Posted on 2020-09-26
586 Haloferax volcanii immersed liquid biofilms develop independently of known biofilm machineries and exhibit rapid honeycomb pattern formation
Schiller, H.; Schulze, S.; Mutan, Z.; de Vaulx, C.; Runcie, C.; Schwartz, J.; Rados, T.; Bisson Filho, A. W.; Pohlschroder, M.
10.1101/2020.07.18.206797 — microbiology — Posted on 2020-09-26
589 Fluid and crystallised intelligence are associated with distinct regionalisation patterns of cortical morphology
Palmer, C. E.; Zhao, W.; Loughnan, R. J.; Zou, J.; Fan, C.-C.; Thompson, W. K.; Dale, A. M.; Jernigan, T. L.
10.1101/2020.02.13.948596 — neuroscience — Posted on 2020-09-26
590 Translatomic database of cortical astroglia across male and female mouse development reveals two distinct developmental phenotypes
Rurak, G. M.; Simard, S.; Charih, F.; Van Geel, A.; Stead, J.; Woodside, B.; Green, J. R.; Coppola, G.; Salmaso, N.
10.1101/681684 — neuroscience — Posted on 2020-09-26
592 Molecular underpinnings of ssDNA specificity by Rep HUH endonucleases and implications for HUH-tag multiplexing and engineering
Tompkins, K. J.; Houtti, M.; Litzau, L. A.; Aird, E. J.; Everett, B. A.; Nelson, A. T.; Pornschloegl, L.; Limon-Swanson, L. K.; Evans, R. L.; Evans, K.; Shi, K.; Aihara, H.; Gordon, W. R.
10.1101/2020.09.01.278671 — biophysics — Posted on 2020-09-26
593 LIQA: Long-read Isoform Quantification and Analysis
Hu, Y.; Fang, L.; Chen, X.; Zhong, J. F.; Li, M.; Wang, K.
10.1101/2020.09.09.289793 — bioinformatics — Posted on 2020-09-26
594 A Modular Framework for Multiscale Spatial Modeling of Viral Infection and Immune Response in Epithelial Tissue
Sego, T. J.; Aponte-Serrano, J. O.; Ferrari Gianlupi, J.; Heaps, S.; Breithaupt, K.; Brusch, L.; Crawshaw, J.; Osborne, J. M.; Quardokus, E. M.; Plemper, R. K.; Glazier, J. A.
10.1101/2020.04.27.064139 — bioengineering — Posted on 2020-09-26
595 Pentapeptide repeat proteins QnrB1 and AlbG require ATP hydrolysis to rejuvenate poisoned gyrase complexes
Mazurek, L.; Ghilarov, D. A.; Michalczyk, E.; Pakosz, Z.; Czyszczon, W.; Wawro, K.; Behroz, I.; Suessmuth, R. D.; Heddle, J. G.
10.1101/2020.09.24.310243 — biochemistry — Posted on 2020-09-26
596 Identification of new therapeutic targets in CRLF2-overexpressing B-ALL through discovery of2 TF-gene regulatory interactions.
Badri, S.; Carella, B.; Lhoumaud, P.; Castro, D. M.; Gibbs, C. S.; Raviram, R.; Narang, S.; Evensen, N.; Watters, A.; Carroll, W.; Bonneau, R. M.; Skok, J. A.
10.1101/654418 — genomics — Posted on 2020-09-26
597 Samplot: A Platform for Structural Variant Visual Validation and Automated Filtering
Belyeu, J. R.; Chowdhury, M.; Brown, J.; Pedersen, B. S.; Cormier, M. J.; Quinlan, A.; Layer, R. M.
10.1101/2020.09.23.310110 — genetics — Posted on 2020-09-26
598 Population Genomic Analyses Separate Historic Translocations from Contemporary Gene Flow in Arkansas White-tailed Deer (Odocoileus virginianus)
Chafin, T. K.; Zbinden, Z. D.; Douglas, M. R.; Martin, B. T.; Middaugh, C. R.; Gray, M. C.; Ballard, J. R.; Douglas, M. E.
10.1101/2020.09.22.308825 — evolutionary biology — Posted on 2020-09-26
599 The conspicuousness of the toxic Heliconius butterflies across time and habitat
Dalbosco Dell'Aglio, D.; Troscianko, J.; Stevens, M.; McMillan, W. O.; Jiggins, C. D.
10.1101/662155 — ecology — Posted on 2020-09-26
600 Nutrient Export and Periphyton Biomass in a Stream-Lake Basin from the Patagonian Andean Region
Sosnovsky, A.; Lallement, M. E.; Rechencq, M.; Fernandez, M. V.; Zattara, E. E.; Feijoo, C. S.
10.1101/2020.09.07.284893 — ecology — Posted on 2020-09-26
601 RUNX1 marks a luminal castration resistant lineage established at the onset of prostate development
Mevel, R.; Steiner, I.; Mason, S.; Galbraith, L. C. A.; Patel, R.; Fadlullah, M.; Ahmad, I.; Leung, H. Y.; Oliveira, P.; Blyth, K.; Baena, E.; Lacaud, G.
10.1101/2020.06.19.161604 — developmental biology — Posted on 2020-09-26
608 Rapid toxin sequestration modifies poison frog physiology
O'Connell, L. A.; LS50: Integrated Science Laboratory Course, ; O'Connell, J. D.; Paulo, J. A.; Trauger, S. A.; Gygi, S. P.; Murray, A. W.
10.1101/2020.05.27.119081 — physiology — Posted on 2020-09-26
609 Universal MS/MS Visualization and Retrieval with the Metabolomics Spectrum Resolver Web Service
Bittremieux, W.; Chen, C.; Dorrestein, P. C.; Schymanski, E. L.; Schulze, T.; Neumann, S.; Meier, R.; Rogers, S.; Wang, M.
10.1101/2020.05.09.086066 — bioinformatics — Posted on 2020-09-26
611 Meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex
Smith, R.; Pishva, E.; Shireby, G.; Smith, A. R.; Roubroeks, J. A. Y.; Hannon, E.; Wheildon, G.; Mastroeni, D.; Gasparoni, G.; Riemenschneider, M.; Giese, A.; Sharp, A. J.; Schalkwyk, L. C.; Haroutunian, V.; Viechtbauer, W.; van den Hove, D.; Weedon, M. N.; Brokaw, D.; Francis, P. T.; Thomas, A. J.; Love, S.; Morgan, K.; Walter, J.; Coleman, P. D.; Bennett, D. A.; De Jager, P.; Mill, J.; Lunnon, K.
10.1101/2020.02.28.957894 — genomics — Posted on 2020-09-26
614 Identification of trans-AT polyketide clusters in two marine bacteria reveals cryptic similarities between distinct symbiosis factors
Kacar, D.; Canedo, L. M.; Rodriguez, P.; Gonzalez, E.; Galan, B.; Schleissner, C.; Leopold-Messer, S.; Piel, J.; Cuevas, C.; de la Calle, F.; Garcia, J. L.
10.1101/2020.09.18.303172 — microbiology — Posted on 2020-09-26
617 Genetic architecture of gene regulation in Indonesian populations identifies QTLs associated with local ancestry and archaic introgression
Natri, H. M.; Hudjashov, G.; Jacobs, G.; Kusuma, P.; Saag, L.; Darusallam, C. C.; Metspalu, M.; Sudoyo, H.; Cox, M. P.; Gallego Romero, I.; Banovich, N. E.
10.1101/2020.09.25.313726 — genomics — Posted on 2020-09-25
624 Regulation of gene transcription by thyroid hormone receptor β agonists in clinical development for the treatment of non-alcoholic steatohepatitis (NASH)
Luong, X. G.; Stevens, S. K.; Jekle, A.; Lin, T.-I.; Gupta, K.; Misner, D.; Chanda, S.; Mukherjee, S.; Williams, C.; Stoycheva, A.; Blatt, L. M.; Beigelman, L. N.; Symons, J. A.; Raboisson, P.; McGowan, D.; Vandyck, K.; Deval, J.
10.1101/2020.09.25.312934 — pharmacology and toxicology — Posted on 2020-09-25
627 Comparing mutational pathways to lopinavir resistance in HIV-1 subtypes B versus C
Posada-Cespedes, S.; Van Zyl, G.; Montazeri, H.; Kuipers, J.; Rhee, S.-Y.; Kouyos, R.; Günthard, H. F.; Beerenwinkel, N.
10.1101/2020.09.25.312942 — evolutionary biology — Posted on 2020-09-25
629 A high affinity human monoclonal antibody against Pfs230 binds multiple parasite stages and blocks oocyst formation in mosquitoes
Coelho, C. H.; Tang, W. K.; Burkhardt, M.; Galson, J. D.; Muratova, O.; Salinas, N.; Alves e Silva, T. L.; Reiter, K.; MacDonald, N.; Nguyen, V.; Byrne-Steele, M.; Pan, W.; Hou, X.; Brown, B.; Eisenhower, M.; Han, J.; Jenkins, B.; Doritchamou, J. Y. A.; Smelkinson, M.; Vega-Rodriguez, J.; Truck, J.; Sagara, I.; Renn, J.; Tolia, N.; Duffy, P.
10.1101/2020.09.25.313478 — immunology — Posted on 2020-09-25
631 Role of the SUT1 and SUT2 sugar transporters during stolbur phytoplasma infection in tomato
De Marco, F.; Batailler, B.; Thorpe, M. R.; Razan, F.; LE HIR, R.; Vilaine, F.; Bouchereau, A.; Martin-Magniette, M.-L.; Eveillard, S.; Dinant, S.
10.1101/2020.09.25.309708 — plant biology — Posted on 2020-09-25
632 Loss of RNF43/ZNRF3 predisposes to Hepatocellular carcinoma by impairing liver regeneration and altering liver fat metabolism
Mastrogiovanni, G.; Pacini, C.; Kakava, S.; Arnes-Benito, R.; Bradshaw, C. R.; Davies, S.; Saeb-Parsy, K.; Koo, B.-K.; Huch, M.
10.1101/2020.09.25.313205 — cancer biology — Posted on 2020-09-25
634 Integrated structure-function dataset reveals key mechanisms underlying photochromic fluorescent proteins
De Zitter, E.; Hugelier, S.; Duwe, S.; Vandenberg, W.; Tebo, A. G.; Van Meervelt, L.; Dedecker, P.
10.1101/2020.09.25.313528 — biophysics — Posted on 2020-09-25
636 Structural insights into F-actin regulation and sarcomere assembly via myotilin
Kostan, J.; Pavsic, M.; Puz, V.; Schwarz, T. C.; Drepper, F.; Molt, S.; Graewert, M. A.; Schreiner, C.; Sajko, S.; van der Ven, P. F. M.; Svergun, D.; Warscheid, B.; Konrat, R.; Fuerst, D. O.; Lenarcic, B.; Djinovic-Carugo, K.
10.1101/2020.09.25.310029 — biochemistry — Posted on 2020-09-25
637 A chromosome-level genome assembly for the Pacific oyster (Crassostrea gigas)
Penaloza, C.; Gutierrez, A. P.; Eory, L.; Wang, S.; Guo, X.; Archibald, A. L.; Bean, T. P.; Houston, R. D.
10.1101/2020.09.25.313494 — genomics — Posted on 2020-09-25
639 Host immune responses after suprachoroidal delivery of AAV8 in nonhuman primate eyes
Chung, S. H.; mollhoff, I. n.; Mishra, A.; Sin, T.-n.; Ngo, T.; Ciulla, T.; Sieving, P.; Thomasy, S. M.; Yiu, G.
10.1101/2020.09.25.313676 — genetics — Posted on 2020-09-25
642 LAP2alpha maintains a mobile and low assembly state of A-type lamins in the nuclear interior
Naetar, N.; Georgiou, K.; Knapp, C.; Bronshtein, I.; Zier, E.; Fichtinger, P.; Dechat, T.; Garini, Y.; Foisner, R.
10.1101/2020.09.25.313296 — cell biology — Posted on 2020-09-25
644 Microbial map of the world's vineyards:Applying the concept of microbial terroir on a global scale
Gobbi, A.; Acedo, A.; Imam, N.; Santini, R. G.; Ortiz-Alvarez, R.; Ellegaard-Jensen, L.; Belda, I.; Hansen, L. H.
10.1101/2020.09.25.313288 — microbiology — Posted on 2020-09-25
645 CARD8 inflammasome mediates pyroptosis of HIV-1-infected cells by sensing viral protease activity
Wang, Q.; Gao, H.; Clark, K. M.; Tang, P.; Harlan, G. H.; Kutluay, S. B.; DeSelm, C. J.; Presti, R. M.; Shan, L.
10.1101/2020.09.25.308734 — immunology — Posted on 2020-09-25
646 Virus-Like Particle Based-Vaccines Elicit Neutralizing Antibodies against the HIV-1 Fusion Peptide
Mogus, A. T.; Liu, L.; Jia, M.; Ajayi, D. T.; Xu, K.; Kong, R.; Huang, J.; Yu, J.; Kwong, P. D.; Mascola, J. R.; Ho, D. D.; Tsuji, M.; Chackerian, B.
10.1101/2020.09.25.308957 — immunology — Posted on 2020-09-25
647 LSD1 promotes secretory cell specification to drive BRAF mutant colorectal cancer
Miller, S. A.; Policastro, R. A.; Sriramkumar, S.; Lai, T.; Huntington, T. D.; Ladaika, C. A.; Zentner, G. E.; O'Hagan, H. M.
10.1101/2020.09.25.313536 — cancer biology — Posted on 2020-09-25
648 The level of oncogenic Ras controls the malignant transformation of Lkb1 mutant tissue in vivo.
Rackley, B.; Seong, C.-S.; Kiely, E.; Parker, R. E.; Rupji, M.; Dwivedi, B.; Heddleston, J. M.; Giang, W.; Anthony, N.; Chew, T.-L.; Gilbert-Ross, M.
10.1101/2020.09.25.308080 — cancer biology — Posted on 2020-09-25
651 METTL3 inhibitors for epitranscriptomic modulation of cellular processes
Moroz-Omori, E. V.; Huang, D.; Bedi, R. K.; Cheriyamkunnel, S. J.; Bochenkova, E.; Dolbois, A.; Rzeczkowski, M. D.; Wiedmer, L.; Sledz, P.; Caflisch, A.
10.1101/2020.09.25.311803 — biochemistry — Posted on 2020-09-25
654 Effectively control of viral disease outbreak in shrimp culture system by selective predation
Chen, Y. G.; Wang, M.; Zhao, Z.; Weng, S. P.; Yang, J. C.; Liu, S. Y.; Liu, C.; Yuan, F. H.; Ai, B.; Zhang, H. Q.; Zhang, M. Y.; Lu, L. R.; Yuan, K.; Yu, Z. L.; Mo, B. B.; Zhong, Z. W.; Zheng, L. W.; Feng, G. C.; Li, S. C.; He, J. G.
10.1101/2020.09.24.311563 — ecology — Posted on 2020-09-25
655 Single cell analysis reveals the impact of age and maturation stage on the human oocyte transcriptome
Llonch, S.; Barragan, M.; Nieto, P.; Mallol, A.; Elosua-Bayes, M.; Lorden, P.; Ruiz, S.; Zambelli, F.; Heyn, H.; Vassena, R.; Payer, B.
10.1101/2020.09.25.309658 — developmental biology — Posted on 2020-09-25
656 Reduced competence to arboviruses following the sustainable invasion of Wolbachia into native Aedes aegypti from Niteroi, Southeastern Brazil
Gesto, J. S. M.; Ribeiro, G. S.; Rocha, M. N.; Dias, F. B. S.; Peixoto, J.; Carvalho, F. D.; Pereira, T. N.; Moreira, L. A.
10.1101/2020.09.25.312207 — microbiology — Posted on 2020-09-25
659 SARS-CoV-2 and Malayan pangolin coronavirus infect human endoderm, ectoderm and induced lung progenitor cells
Xiang, K.; Hong, B.; Lai, X.; Chen, Y.; Luo, T.; An, X.; Song, L.; Zhuang, H.; Fan, H.; Li, T.; Tong, Y.-G.
10.1101/2020.09.25.313270 — microbiology — Posted on 2020-09-25
660 Altered basal lipid metabolism underlies the functional impairment of naive CD8+ T cells in elderly humans
Nicoli, F.; Cabral-Piccin, M.; Papagno, L.; Gallerani, E.; Folcher, V.; Dubois, M.; Clave, E.; Vallet, H.; Frere, J.; Gostick, E.; Llewellyn-Lacey, S.; Price, D.; Toubert, A.; Boddaert, J.; Caputo, A.; Gavioli, R.; Appay, V.
10.1101/2020.09.24.311704 — immunology — Posted on 2020-09-25
661 Single-cell characterization of transcriptomic heterogeneity in lymphoblastoid cell lines
Sorelle, E. D.; Dai, J.; Zhou, J. Y.; Giamberardino, S.; Bailey, J. A.; Gregory, S.; Chan, C.; Luftig, M. A.
10.1101/2020.09.24.311886 — immunology — Posted on 2020-09-25
664 Degeneracy and stability in neural circuits of neuromodulators
Behera, C. K.; Joshi, A.; Wang, D.-H.; Sharp, T.; Wong-Lin, K.
10.1101/2020.09.25.313999 — neuroscience — Posted on 2020-09-25
666 Revealing the Key Regulators of Cell Identity in the Human Adult Pancreas
Vanheer, L.; Schiavo, A. A.; Van Haele, M.; Haesen, T.; Janiszewski, A.; Chappell, J.; Roskams, T.; Cnop, M.; Pasque, V.
10.1101/2020.09.23.310094 — bioinformatics — Posted on 2020-09-25
667 Field testing of biohybrid robotic jellyfish to demonstrate enhanced swimming speeds
Xu, N. W.; Townsend, J. P.; Costello, J. H. H.; Colin, S.; Gemmell, B.; Dabiri, J. O.
10.1101/2020.09.24.312322 — bioengineering — Posted on 2020-09-25
675 Nitazoxanide and JIB-04 have broad-spectrum antiviral activity and inhibit SARS-CoV-2 replication in cell culture and coronavirus pathogenesis in a pig model
Son, J.; Huang, S.; Zeng, Q.; Bricker, T. L.; Case, J. B.; Zhou, J.; Zang, R.; Liu, Z.; Chang, X.; Harastani, H. H.; Chen, L.; Gomez Castro, M. F.; Zhao, Y.; Kohio, H. P.; Hou, G.; Fan, B.; Niu, B.; Guo, R.; Rothlauf, P. W.; Bailey, A. L.; Wang, X.; Shi, P.-Y.; Whelan, S. P. J.; Diamond, M. S.; Boon, A. C. M.; Li, B.; Ding, S.
10.1101/2020.09.24.312165 — microbiology — Posted on 2020-09-25
677 A potent SARS-CoV-2 neutralizing human monoclonal antibody that reduces viral burden and disease severity in Syrian hamsters
Fagre, A.; Manhard, J.; Adams, R.; Eckley, M.; Zhan, S.; Lewis, J.; Rocha, S. M.; Woods, C.; Kuo, K.; Liao, W.; Li, L.; Corper, A.; Challa, D.; Mount, E.; Tumanut, C.; Tjalkens, R. B.; Aboelleil, T.; Fan, X.; Schountz, T.
10.1101/2020.09.25.313601 — microbiology — Posted on 2020-09-25
678 Cyclooxgenase-2 is induced by SARS-CoV-2 infection but does not affect viral entry or replication
Chen, J. S.; Alfajaro, M. M.; Wei, J.; Chow, R. D.; Filler, R. B.; Eisenbarth, S. C.; Wilen, C. B.
10.1101/2020.09.24.312769 — microbiology — Posted on 2020-09-25
680 SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial derived cells and cardiomyocytes
Li, Y.; Renner, D.; Comar, C. E.; Whelan, J.; Reyes, H.; Cardenas-Diaz, F. L.; Truitt, R.; Tan, L. H.; Dong, B.; Alysandratose, K. D.; Huang, J.; Palmer, J. N.; Adappa, N. D.; Kohanski, M. A.; Kotton, D. N.; Silverman, R. H.; Yang, W.; Morrisey, E.; Cohen, N.; Weiss, S. R.
10.1101/2020.09.24.312553 — microbiology — Posted on 2020-09-25
681 Prophylactic intranasal administration of a TLR2 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model
Proud, P. C.; Tsitoura, D.; Watson, R. J.; Chua, B. Y.; Aram, M. J.; Bewley, K. R.; Cavell, B. E.; Cobb, R.; Dowall, S.; Fotheringham, S. A.; Ho, C. M.; Lucas, V.; Ngabo, D.; Rayner, E.; Ryan, K. A.; Slack, G. S.; Thomas, S.; Wand, N. I.; Yeates, P.; Demaison, C.; Jackson, D. C.; Bartlett, N. W.; Mercuri, F.; Carroll, M. W.
10.1101/2020.09.25.309914 — immunology — Posted on 2020-09-25
682 Development of antibody-dependent cell cytotoxicity function in HIV-1 antibodies
Doepker, L. E.; Danon, S.; Harkins, E.; Ralph, D.; Yaffe, Z.; Dhar, A.; Wagner, C.; Stumpf, M.; Arenz, D.; Williams, J. A.; Jaoko, W.; Mandaliya, K.; Lee, K. K.; Matsen, F. A.; Overbaugh, J.
10.1101/2020.09.24.312066 — immunology — Posted on 2020-09-25
683 Representational drift in primary olfactory cortex
Schoonover, C. E.; Ohashi, S. N.; Axel, R.; Fink, A. J. P.
10.1101/2020.09.24.312132 — neuroscience — Posted on 2020-09-25
688 The energetics of social signaling during roost location in Spix's disc-winged bats
Chaverri, G.; Iturralde-Polit, P.; Sandoval Herrera, N. I.; Romero, A.; Chaves-Ramirez, S.; Sagot, M.
10.1101/2020.09.24.312496 — physiology — Posted on 2020-09-25
690 Surface condensation of a pioneer transcription factor on DNA
Morin, J. A.; Wittmann, S.; Choubey, S.; Klosin, A.; Golfier, S.; Hyman, A. A.; Julicher, F.; Grill, S. W.
10.1101/2020.09.24.311712 — biophysics — Posted on 2020-09-25
691 Evolution of ST-4821 clonal complex hyperinvasive and quinolone-resistant meningococci: the next meningococcal pandemic?
Chen, M.; Harrison, O.; Bratcher, H.; Bo, Z.; Jolley, K. A.; Rodrigues, C. M.; Bray, J.; Guo, Q.; Zhang, X.; Chen, M.; Maiden, M. C.
10.1101/2020.09.24.312546 — bioinformatics — Posted on 2020-09-25
694 Harnessing Ionic Selectivity In Acetyltransferase Chemoproteomic Probes
Jing, Y.; Montano, J. L.; Levy, M. J.; Lopez, J.; Kung, P.-P.; Richardson, P.; Krajewski, K.; Florens, L.; Washburn, M.; Meier, J. L.
10.1101/2020.09.24.311530 — biochemistry — Posted on 2020-09-25
698 Lamprey Lecticans Link New Vertebrate Genes to the Origin and Elaboration of Vertebrate Tissues
Root, Z. D.; Jandzik, D.; Allen, C.; Brewer, M.; Romasek, M.; Square, T. A.; Medeiros, D. M.
10.1101/2020.09.24.311837 — evolutionary biology — Posted on 2020-09-25
700 Social networks strongly predict the gut microbiota of wild mice
Raulo, A.; Allen, B.; Troitsky, T.; Husby, A.; Firth, J.; Coulson, T.; Knowles, S.
10.1101/2020.09.24.311357 — ecology — Posted on 2020-09-25
703 Temperature and elemental sulfur shape microbial communities in two extremely acidic aquatic volcanic environments
Rojas-Gätjens, D.; Arce-Rodriguez, A.; Puente-Sanchez, F.; Avendano, R.; Libby, E.; Mora-Amador, R.; Rojas-Jimenez, K.; Fuentes-Schweizer, P.; Pieper, D. H.; Chavarria, M.
10.1101/2020.09.24.312660 — microbiology — Posted on 2020-09-25
704 Neutralizing activity of broadly neutralizing anti-HIV-1 antibodies against primary African isolates
Lorenzi, J. C. C.; Mendoza, P.; Cohen, Y. Z.; Nogueira, L.; Lavine, C.; Sapiente, J.; Seaman, M.; Wiatr, M.; Mugo, N. R.; Mujugira, A.; Delany, S.; Lingappa, J. R.; Celum, C.; Caskey, M.; Nussenzweig, M. C.
10.1101/2020.09.24.310938 — immunology — Posted on 2020-09-25
705 Cortical field potential dynamic driving human sensory, motor and cognitive functions
Willumsen, A.; Midtgaard, J.; Jespertsen, B.; Hansen, C. K. K.; Lam, S. N.; Hansen, S.; Kupers, R.; Fabricius, M. E.; Litman, M.; Pinborg, L.; Tascon-Vidarte, J. D.; Sabers, A.; Roland, P. E.
10.1101/2020.09.24.309468 — neuroscience — Posted on 2020-09-25
706 Associations between ADHD symptom remission and white matter microstructure: a longitudinal analysis
Damatac, C. G.; Leenders, A. E. M.; Soheili-Nezhad, S.; Chauvin, R. J. M.; Mennes, M. J. J.; Zwiers, M. P.; van Rooij, D.; Akkermans, S. E. A.; Naaijen, J.; Franke, B.; Buitelaar, J. K.; Beckmann, C. F.; Sprooten, E.
10.1101/2020.09.24.311654 — neuroscience — Posted on 2020-09-25
709 Multi-scale Modeling Toolbox for Single Neuron and Subcellular Activity under (repetitive) Transcranial Magnetic Stimulation
Shirinpour, S.; Hananeia, N.; Rosado, J.; Galanis, C.; Vlachos, A.; Jedlicka, P.; Queisser, G.; Opitz, A.
10.1101/2020.09.23.310219 — neuroscience — Posted on 2020-09-25
710 Hedonic representations in primary somatosensory cortices; Pain but not pleasure?
Kryklywy, J.; Ehlers, M. R.; Beukers, A. O.; Moore, S. R.; Todd, R.; Anderson, A. K.
10.1101/2020.09.24.310383 — neuroscience — Posted on 2020-09-25
714 Chickpea (Cicer arietinum L.) root system architecture adaptation to initial soil moisture improves seed development in dry-down conditions
Bontpart, T.; Robertson, I.; Giuffrida, V.; Concha, C.; Scorza, L. C. T.; McCormick, A. J.; Fikre, A.; Tsaftaris, S. A.; Doerner, P. W.
10.1101/2020.09.24.311753 — plant biology — Posted on 2020-09-25
715 The effects of low-carbohydrate diets on the metabolic response to androgen-deprivation therapy in prostate cancer
Chi, J.-T. A.; Lin, P.-H.; Tolstikov, V.; Oyekunle, T.; Galvan, G.; Ramirez-Torres, A.; Chen, E.; Bussberg, V.; Chi, B.; Greenwood, B.; Sarangarajan, R.; Narain, N.; Kiebish, M.; Freedland, S.
10.1101/2020.09.23.304360 — cancer biology — Posted on 2020-09-25
719 Three-Dimensional Impedance Tomographic Mapping of Metabolically Active Endolumen
Abiri, P.; Luo, Y.; Huang, Z.-Y.; Roustaei, M.; Duarte-Vogel, S.; Cui, Q.; Packard, R. R. S.; Ebrahimi, R.; Benharash, P.; Tai, Y.-C.; Hsiai, T. K.
10.1101/2020.09.24.312025 — bioengineering — Posted on 2020-09-25
720 Primary saturation of α,β-unsaturated carbonyl containing fatty acids does not abolish electrophilicity
Snyder, N. W.; Singh, B.; Buchan, G.; O'Brien, J.; Arroyo, A. D.; Liu, X.; Sobol, R. W.; Blair, I. A.; Mesaros, C. A.; Wendell, S. G.
10.1101/2020.09.24.311985 — biochemistry — Posted on 2020-09-25
722 Soundscapes predict species occurrence in tropical forests
Sethi, S. S.; Ewers, R. M.; Jones, N. S.; Sleutel, J.; Shabrani, A.; Zulkifli, N.; Picinali, L.
10.1101/2020.09.24.311381 — ecology — Posted on 2020-09-25
723 A survey of proximal methods for monitoring leaf phenology in temperate deciduous forests
Soudani, K.; Delpierre, N.; Berveiller, D.; Hmimina, G.; Pontailler, J.-Y.; Seureau, L.; Vincent, G.; Dufrene, E.
10.1101/2020.09.24.311191 — ecology — Posted on 2020-09-25
724 Action imitation via trajectory-based or posture-based planning
Barhorst-Cates, E. M.; Isaacs, M. W.; Buxbaum, L. J.; Wong, A. L.
10.1101/2020.09.23.308635 — neuroscience — Posted on 2020-09-25
725 Single-cell transcriptomics, scRNA-Seq and C1 CAGE discovered distinct phases of pluripotency during naïve-to-primed conversion in mice
Böttcher, M.; Tada, Y.; Moody, J.; Kondo, M.; Ura, H.; Abugessaisa, I.; Kasukawa, T.; Hon, C.-C.; Nagao, K.; Carninci, P.; Abe, K.
10.1101/2020.09.25.313239 — genomics — Posted on 2020-09-25
726 Ribosomal protein S7 ubiquitination during ER stress in yeast is associated with selective mRNA translation and stress outcome
Matsuki, Y.; Matsuo, Y.; Nakano, Y.; Iwasaki, S.; Yoko, H.; Udagawa, T.; Li, S.; Saeki, Y.; Yoshihisa, T.; Tanaka, K.; Ingolia, N.; Inada, T.
10.1101/2020.09.24.311365 — molecular biology — Posted on 2020-09-25
730 Plasticity of the primary metabolome in 241 cold grown Arabidopsis thaliana accessions and its relation to natural habitat temperature
Weiszmann, J.; Clauw, P.; Jagoda, J.; Reichardt-Gomez, I.; Koemeda, S.; Jez, J.; Nordborg, M.; Walther, D.; Naegele, T.; Weckwerth, W.
10.1101/2020.09.24.311092 — plant biology — Posted on 2020-09-25
731 Oxicam-type nonsteroidal anti-inflammatory drugs inhibit NPR1-mediated salicylic acid pathway
Ishihama, N.; Choi, S.-w.; Noutoshi, Y.; Saska, I.; Asai, S.; Takizawa, K.; He, S.-Y.; Osada, H.; Shirasu, K.
10.1101/2020.09.25.311100 — plant biology — Posted on 2020-09-25
736 Systematic analysis of key parameters for genomics-based real-time detection and tracking of multidrug-resistant bacteria
Gorrie, C. L.; Goncalves da Silva, A.; Ingle, D. J.; Higgs, C.; Seeman, T.; Stinear, T. P.; Williamson, D. A.; Kwong, J. C.; Grayson, M. L.; Sherry, N. L.; Howden, B.
10.1101/2020.09.24.310821 — genomics — Posted on 2020-09-25
738 Samplot: A Platform for Structural Variant Visual Validation and Automated Filtering
Belyeu, J. R.; Chowdhury, M.; Brown, J.; Pedersen, B. S.; Cormier, M. J.; Quinlan, A.; Layer, R. M.
10.1101/2020.09.23.310110 — genetics — Posted on 2020-09-25
741 Human marginal zone B cell development from early T2 progenitors
Tull, T. J.; Pitcher, M. J.; Guesdon, W.; Siu, J. H.; Lebrero-Fernandez, C.; Zhao, Y.; Petrov, N.; Heck, S.; Ellis, R.; Dhami, P.; Kadolsky, U. D.; Kleeman, M.; Kamra, Y.; Fear, D. J.; John, S.; Jassem, W.; Groves, R. W.; Sanderson, J. D.; Robson, M. D.; D'Cruz, D.; Bemark, M.; Spencer, J.
10.1101/2020.09.24.311498 — cell biology — Posted on 2020-09-25
743 Mitochondrial alternative oxidase contributes to successful tardigrade anhydrobiosis
Wojciechowska, D.; Karachitos, A.; Roszkowska, M.; Rzezniczak, W.; Sobkowiak, R.; Kaczmarek, L.; Kosicki, J.; Kmita, H.
10.1101/2020.09.25.313122 — cell biology — Posted on 2020-09-25
747 IL-7R signalling activates widespread VH and DH gene usage to drive antibody diversity in bone marrow B cells
Baizan Edge, A.; Stubbs, B. A.; Stubbington, M. J. T.; Bolland, D. J.; Tabbada, K.; Andrews, S.; Corcoran, A. E.
10.1101/2020.09.24.298000 — immunology — Posted on 2020-09-25
748 Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade
Palmer, D. C.; Webber, B. R.; Patel, Y.; Johnson, M. J.; Kariya, C. M.; Lahr, W. S.; Parkhurst, M. R.; Gartner, J. J.; Prickett, T. D.; Lowery, F. J.; Kishton, R. J.; Gurusamy, D.; Franco, Z.; Vodnala, S. K.; Diers, M. D.; Wolf, N. K.; Slipek, N. J.; McKenna, D. H.; Sumstad, D.; Viney, L.; Henley, T.; Burckstummer, T.; Baker, O.; Hu, Y.; Yan, C.; Meerzaman, D.; Padhan, K.; Lo, W.; Malekzadeh, P.; Jia, L.; Deniger, D. C.; Patel, S. J.; Robbins, P. F.; McIvor, R. S.; Choudhry, M.; Rosenberg, S. A.; Moriarity, B. S.; Restifo, N. P.
10.1101/2020.09.24.306571 — immunology — Posted on 2020-09-25
749 Temporal evolution of single-cell transcriptomes of Drosophila olfactory projection neurons
Xie, Q.; Brbic, M.; Horns, F.; Kolluru, S. S.; Jones, B.; Li, J.; Reddy, A.; Xie, A.; Kohani, S.; Li, Z.; McLaughlin, C.; Li, T.; Xu, C.; Vacek, D.; Luginbuhl, D. J.; Leskovec, J.; Quake, S.; Luo, L.; Li, H.
10.1101/2020.09.24.312397 — neuroscience — Posted on 2020-09-25
750 NMJ-Analyser: high-throughput morphological screening of neuromuscular junctions identifies subtle changes in mouse neuromuscular disease models
Mejia Maza, A.; Jarvis, S.; Lee, W. C.; Cunningham, T. J.; Schiavo, G.; Secrier, M.; Fratta, P.; Sleigh, J. N.; Sudre, C. H.; Fisher, E. M. C.
10.1101/2020.09.24.293886 — neuroscience — Posted on 2020-09-25
751 An early cortical progenitor-specific mechanism regulates thalamocortical innervation
Pal, S.; Dwivedi, D.; Pramanik, T.; Godbole, G.; Iwasato, T.; Jabaudon, D.; Bhalla, U. S.; Tole, S.
10.1101/2020.09.25.312785 — neuroscience — Posted on 2020-09-25
752 IF1 connects obesity and insulin resistance through mitochondrial reprogramming in association with ANT2
Wang, Y.; Guan, Y.; Zhang, J.; Cao, X.; Shen, S.; Zhong, G.; Xong, X.; Xu, Y.; Zhang, X.; Wang, H.; Ye, J.
10.1101/2020.09.24.311076 — physiology — Posted on 2020-09-25
753 Incorporation of a Biocompatible Nanozyme in Cellular Antioxidant Enzyme Cascade Reverses Huntington's Like Disorder in Preclinical Model
Adhikari, A.; Mondal, S.; Das, M.; Biswas, P.; Pal, U.; Darbar, S.; Bhattacharya, S. S.; Pal, D.; Saha-Dasgupta, T.; Das, A. K.; Mallick, A. K.; Pal, S. K.
10.1101/2020.09.23.310995 — pharmacology and toxicology — Posted on 2020-09-25
754 Pharmacological targeting of host chaperones protects from pertussis toxin in vitro and in vivo
Ernst, K.; Mittler, A.-K.; Winkelmann, V.; Eberhardt, N.; Anastasia, A.; Sonnabend, M.; Lochbaum, R.; Wirsching, J.; Skerry, C.; Carbonetti, N. H.; Frick, M.; Barth, H.
10.1101/2020.09.24.303321 — pharmacology and toxicology — Posted on 2020-09-25
755 Homing Choices of Breast Cancer Cells Revealed by Tissue Specific Invasion and Extravasation Lab-on-a-chip Platforms
Firatligil-Yildirir, B.; Bati-Ayaz, G.; Tahmaz, I.; Bilgen, M.; Pesen-Okvur, D.; Yalcin-Ozuysal, O.
10.1101/2020.09.25.312793 — cancer biology — Posted on 2020-09-25
756 NIAGADS Alzheimer's GenomicsDB: A resource for exploring Alzheimer's Disease genetic and genomic knowledge
Greenfest-Allen, E.; Klamann, C.; Valladares, O.; Kuzma, A.; Gangadharan, P.; Leung, Y. Y.; Stoeckert, C. J.; Wang, L.-S.
10.1101/2020.09.23.310276 — bioinformatics — Posted on 2020-09-25
758 Dual-view oblique plane microscopy (dOPM)
Sparks, H.; Dent, L.; Bakal, C.; Behrens, A.; Salbreux, G.; Dunsby, C.
10.1101/2020.09.24.311613 — bioengineering — Posted on 2020-09-25
760 Beam image-shift accelerated data acquisition for near-atomic resolution single-particle cryo-electron tomography
Bouvette, J.; Liu, H.-F.; Du, X.; Zhou, Y.; Sikkema, A. P.; Rezende E Mello, J. D. F.; Klemm, B.; Huang, R.; Schaaper, R. M.; Borgnia, M. J.; Bartesaghi, A.
10.1101/2020.09.24.294983 — biochemistry — Posted on 2020-09-25
767 MSH2 knock-down shows CTG repeat stability and concomitant upstream demethylation at the DMPK locus in myotonic dystrophy type 1 human embryonic stem cells
Franck, S.; BarbE, L.; Ardui, S.; De Vlaeminck, Y.; Allemeersch, J.; Dziedzicka, D.; Spits, C.; Vanroye, F.; Hilven, P.; Duque, G.; Vermeesch, J. R.; Gheldof, A.; Sermon, K. D.
10.1101/2020.09.25.313197 — genetics — Posted on 2020-09-25
771 Mechanisms and heterogeneity of mineral use by natural colonies of the cyanobacterium Trichodesmium
Held, N.; Sutherland, K. M.; Webb, E. A.; McIlvin, M. M.; Cohen, N. R.; Devaux, A. J.; Hutchins, D. A.; Waterbury, J. B.; Hansel, C. M.; Saito, M.
10.1101/2020.09.24.295147 — ecology — Posted on 2020-09-25
773 Rcn3 is Involved in Postnatal Tendon Development by Regulating Collagen Modification and Fibrillogenesis
Park, N. R.; Shetye, S.; Keene, D. R.; Tufa, S.; Hudson, D. M.; Archer, M.; Soslowsky, L. J.; Dyment, N. A.; Joeng, K. S.
10.1101/2020.09.25.313098 — developmental biology — Posted on 2020-09-25
774 TAEL 2.0: An Improved Optogenetic Expression System for Zebrafish
LaBelle, J.; Ramos-Martinez, A.; Shen, K.; Motta-Mena, L. B.; Gardner, K. H.; Materna, S. C.; Woo, S.
10.1101/2020.09.24.312470 — developmental biology — Posted on 2020-09-25
780 DeepEthogram: a machine learning pipeline for supervised behavior classification from raw pixels
Bohnslav, J. P.; Wimalasena, N. K.; Clausing, K. J.; Yarmolinsky, D.; Cruz, T.; Chiappe, E.; Orefice, L. L.; Woolf, C. J.; Harvey, C. D.
10.1101/2020.09.24.312504 — neuroscience — Posted on 2020-09-25
781 A parameter-free statistical test that improves the detection of neuronal responsiveness
Montijn, J. S.; Seignette, K.; Howlett, M. H.; Cazemier, J. L.; Kamermans, M.; Levelt, C. N.; Heimel, J. A.
10.1101/2020.09.24.311118 — neuroscience — Posted on 2020-09-25
783 hcga: Highly Comparative Graph Analysis for network phenotyping
Peach, R. L.; Arnaudon, A.; Schmidt, J. A.; Palasciano, H.; Bernier, N. R.; Jelfs, K.; Yaliraki, S.; Barahona, M.
10.1101/2020.09.25.312926 — systems biology — Posted on 2020-09-25
784 Reappraisal of Spinach-based RNA Visualization in Plants
Yu, Z. A.; Mei, F.; Yan, H.; Chen, Q.; Yao, M.; Liu, S.; Wang, Y.; Zhang, X.; Zhang, P.; Jackson, S.; Shi, N.; Liu, Y.; Hong, Y.
10.1101/2020.09.24.310607 — plant biology — Posted on 2020-09-25
785 Adipocyte REVERBα dictates adipose tissue expansion during obesity
Hunter, A. L.; Pelekanou, C. E.; Barron, N. J.; Northeast, R. C.; Adamson, A.; Downton, P.; Cornfield, T.; Cunningham, P. S.; Hodson, L.; Loudon, A. S. I.; Unwin, R. D.; Iqbal, M.; Ray, D. W.; Bechtold, D. A.
10.1101/2020.09.23.308155 — physiology — Posted on 2020-09-25
786 Spatially-Aware Clustering of Ion Images in Mass Spectrometry Imaging Data Using Deep Learning
Zhang, W.; Claesen, M.; Moerman, T.; Groseclose, M. R.; Waelkens, E.; De Moor, B.; Verbeeck, N.
10.1101/2020.09.25.285619 — bioinformatics — Posted on 2020-09-25
791 ADPriboDB v2.0: An Updated Database of ADP-ribosylated Proteins
Ayyappan, V.; Wat, R.; Barber, C.; Vivelo, C.; Gauch, K.; Visanpattanasin, P.; Cook, G.; Sazeides, C.; Leung, A. K. L.
10.1101/2020.09.24.298851 — bioinformatics — Posted on 2020-09-25
792 Pentapeptide repeat proteins QnrB1 and AlbG require ATP hydrolysis to rejuvenate poisoned gyrase complexes
Mazurek, L.; Ghilarov, D. A.; Michalczyk, E.; Pakosz, Z.; Czyszczon, W.; Wawro, K.; Behroz, I.; Suessmuth, R. D.; Heddle, J. G.
10.1101/2020.09.24.310243 — biochemistry — Posted on 2020-09-25
793 First 3D-Structural Data of Full-length Rod-Outer-Segment Guanylyl Cyclase 1 in Bovine Retina by Cross-linking/Mass Spectrometry
Rehkamp, A.; Taenzler, D.; Tueting, C.; Kastritis, P. L.; Ihling, C. H.; Kipping, M.; Koch, K.-W.; Sinz, A.
10.1101/2020.09.25.312835 — biochemistry — Posted on 2020-09-25
794 Interpretable network-guided epistasis detection
Duroux, D.; Climente-Gonzales, H.; Azencott, C.-A.; Van Steen, K.
10.1101/2020.09.24.310136 — genetics — Posted on 2020-09-25
795 TFIIH kinase CDK7 antagonizes phenotype switching and emergence of drug tolerance in melanoma
Berico, P.; cigrang, m.; Braun, C.; Davidson, G.; Sandoz, j.; Legras, S.; peyresaubes, F.; Robles, C. G.; egly, j.-m.; compe, e.; Davidson, I.; Coin, F.
10.1101/2020.09.24.311431 — cell biology — Posted on 2020-09-25
796 Spec2Vec: Improved mass spectral similarity scoring through learning of structural relationships
Huber, F.; Ridder, L.; Verhoeven, S.; Spaaks, J. H.; Diblen, F.; Rogers, S.; van der Hooft, J. J.
10.1101/2020.08.11.245928 — bioinformatics — Posted on 2020-09-25
798 An online headphone screening test based on dichotic pitch
Milne, A. E.; Bianco, R.; Poole, K. C.; Zhao, S.; Oxenham, A. J.; Billig, A. J.; Chait, M.
10.1101/2020.07.21.214395 — neuroscience — Posted on 2020-09-25
800 Sick Bats Stay Home Alone: Social distancing during the acute phase response in Egyptian fruit bats (Rousettus aegyptiacus)
Moreno, K. R.; Weinberg, M.; Harten, L.; Salinas Ramos, V. B.; Herrera M., L. G.; Czirjak, G. A.; Yovel, Y.
10.1101/2020.07.06.189357 — zoology — Posted on 2020-09-25
803 TopoStats - an automated tracing program for AFM images
Beton, J. G.; Moorehead, R.; Helfmann, L.; Gray, R.; Hoogenboom, B.; Joseph, A. P.; Topf, M.; Pyne, A. L. B.
10.1101/2020.09.23.309609 — biophysics — Posted on 2020-09-25
805 Reduced cue-induced reinstatement of cocaine seeking behavior in Plcb1+/- mice
Cabana-Dominguez, J.; Martin-Garcia, E.; Gallego-Roman, A.; Maldonado, R.; Fernandez-Castillo, N.; Cormand, B.
10.1101/2020.06.18.158964 — animal behavior and cognition — Posted on 2020-09-25
806 A genomic amplification affecting a carboxylesterase gene cluster confers organophosphate resistance in the mosquito Aedes aegypti: from genomic characterization to high-throughput field detection
Cattel, J.; Haberkorn, C.; Laporte, F.; Gaude, T.; Cumer, T.; Renaud, J.; Sutherland, I. W.; Hertz, J. C.; Bonneville, J.-M.; Arnaud, V.; Nous, C.; Fustec, B.; Boyer, S.; Marcombe, S.; David, J.-P.
10.1101/2020.06.08.139741 — evolutionary biology — Posted on 2020-09-25
807 Stretching of the retinal pigment epithelium contributes to zebrafish optic cup morphogenesis
Moreno-Marmol, T.; Ledesma-Terron, M.; Tabanera, N.; Martin-Bermejo, M. J.; Cardozo, M. J.; Cavodeassi, F.; Bovolenta, P.
10.1101/2020.09.23.310631 — developmental biology — Posted on 2020-09-25
808 Dynamic Mechanochemical feedback between curvedmembranes and BAR protein self-organization
Le Roux, A.-L.; Tozzi, C.; Walani, N.; Quiroga, X.; Zalvidea, D.; Trepat, X.; Staykova, M.; Arroyo, M.; Roca-Cusachs, P.
10.1101/2020.09.23.310169 — biophysics — Posted on 2020-09-25
809 Widespread methylation quantitative trait loci and their role in schizophrenia risk
Perzel Mandell, K. A.; Eagles, N. J.; Wilton, R.; Price, A. J.; Semick, S. A.; Collado-Torres, L.; Tao, R.; Han, S.; Szalay, A. S.; Hyde, T. M.; Kleinman, J. E.; Weinberger, D. R.; Jaffe, A. E.
10.1101/2020.09.24.311878 — genomics — Posted on 2020-09-24
810 Ecological implications of removing a concrete gas platform in the North Sea
Coolen, J. W. P.; Bittner, O.; Driessen, F. M. F.; van Dongen, U.; Siahaya, M. S.; de Groot, W.; Mavraki, N.; Bolam, S. G.; van der Weide, B.
10.1101/2020.04.16.044263 — ecology — Posted on 2020-09-25
812 Distinct antibody repertoires against endemic human coronaviruses in children and adults
Khan, T.; Rahman, M.; Al Ali, F.; Huang, S. S.; Ata, M.; Zhang, Q.; Bastard, P.; Liu, Z.; Jouanguy, E.; Beziat, V.; Cobat, A.; Nasrallah, G. K.; Yassine, H.; Smatti, M.; Sayeed, A.; Vandernoot, I.; Goffard, J.-C.; Smits, G.; Migeotte, I.; Haerynck, F.; Meyts, I.; Abel, L.; Casanova, J.-L.; Hasan, M. R.; Marr, N.
10.1101/2020.06.21.163394 — immunology — Posted on 2020-09-24
813 Primate neuronal connections are sparse as compared to mouse
Wildenberg, G. A.; Rosen, M. C.; Lundell, J.; Paukner, D.; Freedman, D. J.; Kasthuri, N.
10.1101/2020.09.24.311852 — neuroscience — Posted on 2020-09-24
815 Network fingerprint of stimulation induced speech impairment in essential tremor
Petry-Schmelzer, J. N.; Jergas, H.; Thies, T.; Steffen, J. K.; Reker, P.; Dafsari, H. S.; Muecke, D.; Fink, G. R.; Visser-Vandewalle, V.; Dembek, T. A.; Barbe, M. T.
10.1101/2020.02.20.958470 — neuroscience — Posted on 2020-09-24
816 Tissue level profile of SARS-CoV-2 antivirals in mice to predict their effects in COVID-19 multiorgan failure
Scherf-Clavel, O.; Kaczmarek, E.; Kinzig, M.; Friedl, B.; Feja, M.; Hoehl, R.; Nau, R.; Holzgrabe, U.; Gernert, M.; Richter, F.; Soergel, F.
10.1101/2020.09.16.299537 — systems biology — Posted on 2020-09-24
818 Genome-wide SNP data unravel the ancestry and signatures of divergent selection in Ghurrah pigs of India
Mehrotra, A.; Bhushan, B.; A, K.; Singh, A.; Panda, S.; Bhati, M.; Panigrahi, M.; Dutt, T.; Mishra, B. P.; Pausch, H.; Kumar, A.
10.1101/2020.09.24.312009 — genomics — Posted on 2020-09-24
819 Was facial width-to-height ratio subject to sexual selection pressures? A life course approach.
Hodges-Simeon, C. R.; Albert, G.; Richardson, G. B.; McHale, T. S.; Weinberg, S. M.; Gurven, M.; Gaulin, S. J. C.
10.1101/2020.09.24.311324 — evolutionary biology — Posted on 2020-09-24
824 The historic range and drivers of decline of the Tapanuli orangutan
Meijaard, E.; Ni'matullah, S.; Dennis, R.; Sherman, J.; Onrizal, O.; Wich, S. A.
10.1101/2020.08.11.246058 — zoology — Posted on 2020-09-24
827 Host-interactor screens of Phytophthora infestans RXLR proteins reveal vesicle trafficking as a major effector-targeted process
Petre, B.; Contreras, M. P.; Bozkurt, T. O.; Schattat, M. H.; Sklenar, J.; Schornack, S.; Abd-El-Haliem, A.; Castells-Graells, R.; Lozano-Duran, R.; Dagdas, Y.; Menke, F.; Jones, A. M. E.; Vossen, J.; Robatzek, S.; Kamoun, S.; Win, J.
10.1101/2020.09.24.308585 — plant biology — Posted on 2020-09-24
829 Adverse drug reactions associated with the use of biological agents
Machado-Alba, J. E.; Jimenez-Morales, A. L.; Moran-Yela, Y. C.; Parrado-Fajardo, I. Y.; Valladales-REstrepo, L. F.
10.1101/2020.09.24.311241 — pharmacology and toxicology — Posted on 2020-09-24
833 Human inbreeding has decreased in time through the Holocene
Ceballos, F. C.; Gurun, K.; Altinisik, N. E.; Gemici, H. C.; Karamurat, C.; Koptekin, D.; Vural, K. B.; Surer, E.; Erdal, Y. S.; Gotherstrom, A.; Ozer, F.; Atakuman, C.; Somel, M.
10.1101/2020.09.24.311597 — genomics — Posted on 2020-09-24
839 Functional monovalency amplifies the pathogenicity of anti-MuSK IgG4 in myasthenia gravis
Vergoossen, D. L. E.; Plomp, J. J.; Gstottner, C.; Fillie-Grijpma, Y. E.; Augustinus, R.; Verpalen, R.; Wuhrer, M.; Parren, P. W. H. I.; Dominguez-Vega, E.; van der Maarel, S. M.; Verschuuren, J. J.; Huijbers, M. G.
10.1101/2020.09.24.296293 — immunology — Posted on 2020-09-24
840 Investigation of anti-IgLON5-induced neurodegenerative changes in human neurons
Ryding, M.; Gamre, M.; Nissen, M. S.; Nilsson, A. C.; Okarmus, J.; Poulsen, A. A. E.; Meyer, M.; Blaabjerg, M.
10.1101/2020.08.27.269795 — neuroscience — Posted on 2020-09-24
842 Endometrial epithelial ARID1A is critical for uterine gland function in early pregnancy establishment
Marquardt, R.; Kim, T.-H.; Yoo, J.-Y.; Teasley, H. E.; Fazleabas, A. T.; Young, S. L.; Lessey, B. A.; Arora, R.; Jeong, J.-W.
10.1101/2020.09.23.308528 — physiology — Posted on 2020-09-24
845 Functionalized bead assay to measure 3-dimensional traction forces during T-cell activation
Aramesh, M.; Mergenthal, S.; Issler, M.; Weber, F.; Plochberger, B.; Qin, X.-H.; Liska, R.; Duda, G.; Huppa, J.; Ries, J.; Schuetz, G.; Klotzsch, E.
10.1101/2020.09.23.310144 — biophysics — Posted on 2020-09-24
850 Ancestry Inference Using Reference Labeled Clusters of Haplotypes
Noto, K.; Wang, Y.; Song, S.; Schraiber, J. G.; Sedghifar, A.; Byrnes, J. K.; Turissini, D. A.; Hong, E. L.; Ball, C. A.
10.1101/2020.09.23.310698 — genomics — Posted on 2020-09-24
856 Stretching of the retinal pigment epithelium contributes to zebrafish optic cup morphogenesis
Bovolenta, P.; Moreno-Marmol, T.; Ledesma-Terron, M.; Tabanera, N.; Martin-Bermejo, M. J.; Cardozo, M. J.; Cavodeassi, F.
10.1101/2020.09.23.310631 — developmental biology — Posted on 2020-09-24
857 Male-biased islet beta cell dysfunction is caused by the MODY MAFA S64F variant inducing premature aging and senescence
Walker, E. M.; Tong, X.; Cha, J.; Guo, M.; Liu, J.-H.; Yu, S.; Iacovazzo, D.; Mauvais-Jarvis, F. M.; Flanagan, S. E.; Korbonits, M.; Stafford, J.; Jacobson, D. A.; Stein, R.
10.1101/2020.06.29.177527 — molecular biology — Posted on 2020-09-24
867 Octopaminergic neurons have multiple targets in Drosophila larval mushroom body calyx and regulate behavioral odor discrimination
Wong, J. Y. H.; Wan, B. A.; Bland, T.; Montagnese, M.; McLachlan, A. D.; O'Kane, C. J.; Zhang, S. W.; Masuda-Nakagawa, L. M.
10.1101/295659 — neuroscience — Posted on 2020-09-24
868 Precision design of single and multi-heme de novo proteins
Hutchins, G. H.; Noble, C. E. H.; Blackburn, H.; Hardy, B.; Landau, C.; Parnell, A. E.; Yadav, S.; Williams, C.; Race, P. R.; Oliveira, S.; Crump, M. P.; Berger-Schaffitzel, C.; Mulholland, A. J.; Anderson, J. L. R.
10.1101/2020.09.24.311514 — synthetic biology — Posted on 2020-09-24
869 Peripheral sgp130-mediated trans-signaling blockade induces obesity and insulin resistance in mice via PPARα suppression
Lanton, T.; Levkovitch-Siany, O.; Udi, S.; Tam, J.; Abramovich, R.; Perles, S.; Williams, E.; Rachmilewitz, J.; Mor, U.; Elinav, E.; Schmidt-Arras, D.; Rehman, A.; Rosenstiel, P.; Giannou, A.; Huber, S.; Rose-John, S.; Galun, E.; Axelrod, J. H.
10.1101/2020.09.24.309716 — physiology — Posted on 2020-09-24
871 Pancreatic Cancer Intrinsic PI3Kα Activity accelerates Metastasis and rewires Macrophage Component
Thibault, B.; Ramos-Delgado, F.; Pons-Tostivint, E.; Therville, N.; Cintas, C.; Arcucci, S.; Cassant-Sourdy, S.; Reyes-Castellanos, G.; Tosolini, M.; Villard, A. V.; Cayron, C.; Baer, R.; Bertrand-Michel, J.; Payen, D.; Yan, H.; Falcomata, C.; Muscari, F.; Bournet, B.; Delord, J.-P.; Aksoy, E.; Carrier, A.; Cordelier, P.; Saur, D.; Basset, C.; Guillermet-Guibert, J.
10.1101/2020.09.23.307884 — cancer biology — Posted on 2020-09-24
872 Across kingdom biased CYP-mediated metabolism via small-molecule ligands docking on P450 oxidoreductase
Jensen, S. B.; Thodberg, S.; Parween, S.; Moses, M. E.; Hansen, C. C.; Thomsen, J.; Sletfjerding, M. B.; Knudsen, C.; Giudice, R. D.; Lund, P. M.; Castano, P. R.; Bustamante, Y. G.; Jorgensen, F. S.; Pandey, A. V.; Laursen, T.; Moller, B. L.; Hatzakis, N. S.
10.1101/2020.09.23.310391 — biophysics — Posted on 2020-09-24
873 Transcriptomic Analysis of Early Stages of Intestinal Regeneration in Holothuria glaberrima
Quispe, D. J.; Medina-Feliciano, J. G.; Cruz-Gonzalez, S.; Ortiz-Zuazaga, H.; Garcia-Arraras, J. E.
10.1101/2020.09.23.310599 — bioinformatics — Posted on 2020-09-24
876 Functional genomic screens identify human host factors for SARS-CoV-2 and common cold coronaviruses
Wang, R.; Simoneau, C. R.; Kulsuptrakul, J.; Bouhaddou, M.; Travisano, K.; Hayashi, J. M.; Carlson-Stevermer, J.; Oki, J.; Holden, K.; Krogan, N. J.; Ott, M.; Puschnik, A. S.
10.1101/2020.09.24.312298 — microbiology — Posted on 2020-09-24
877 Human FcRn expression and Type I Interferon signaling control Echovirus 11 pathogenesis in mice
Wells, A.; Grimes, K.; Kim, K.; Branche, E.; Bakkenist, C.; DePas, W.; Shresta, S.; Coyne, C.
10.1101/2020.09.24.312058 — microbiology — Posted on 2020-09-24
878 New insights into the paradoxical distribution of IRC7 in Saccharomyces cerevisiae and its associated phenotypic and genomic landscapes
Ruiz, J.; de Celis, M.; Martin-Santamaria, M.; Benito-Vazquez, I.; Pontes, A.; Lanza, V. F.; Sampaio, J. P.; Santos, A.; Belda, I.
10.1101/2020.09.24.307892 — microbiology — Posted on 2020-09-24
879 Insights into the diversity and survival strategies of soil bacterial isolates from the Atacama Desert
Reverdy, A.; Hathaway, D.; Jha, J.; Sullivan, J.; Michaels, G.; Diaz Mac-Adoo, D.; Riquelme, C.; Chai, Y.; Godoy, V. G.
10.1101/2020.09.24.312199 — microbiology — Posted on 2020-09-24
881 ATPIF1 inactivation promotes antitumor immunity through metabolic reprogramming of CD8+ T cells
Zhong, G.; Wang, Y.; Zhang, J.; Wang, Y.; Guan, Y.; Shen, S.; Zhang, X.; Cao, X.; Li, Y.; Wu, M.; Zhang, Z.; Shi, M.; Huang, Y.; Liao, Y.; Liang, Y.; Wang, H.; Ye, J.
10.1101/2020.09.23.310979 — immunology — Posted on 2020-09-24
883 Organization of cortico-hippocampal networks in the human brain
Barnett, A. J.; Reilly, W.; Dimsdale-Zucker, H.; Mizrak, E.; Reagh, Z.; Ranganath, C.
10.1101/2020.06.09.142166 — neuroscience — Posted on 2020-09-24
884 The involvement of neuroimmune cells in adipose innervation
Blaszkiewicz, M.; Wood, E.; Koizar, S.; Willows, J. W.; Anderson, R.; Tseng, Y.-H.; Godwin, J.; Townsend, K.
10.1101/787234 — neuroscience — Posted on 2020-09-24
886 Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death
Meyer, N.; Henkel, L.; Linder, B.; Zielke, S.; Tascher, G.; Trautmann, S.; Geisslinger, G.; Munch, C.; Fulda, S.; Tegeder, I.; Kogel, D.
10.1101/2020.09.23.309617 — cancer biology — Posted on 2020-09-24
887 Oncogenic Activation of AKT by MAPK6
Cai, Q.; Wang, W.; Dong, B.; Zhou, W.; Shen, T.; Moore, D. D.; Creighton, C. J.; Yang, F.
10.1101/2020.09.23.309518 — cancer biology — Posted on 2020-09-24
889 Chitin Biosynthesis Genes in Diaphorina citri
Miller, S.; Tamayo, B.; Shippy, T.; Hosmani, P. S.; Flores-Gonzalez, M.; Mueller, L. A.; Hunter, W. B.; D'elia, T.; Brown, S. J.; Saha, S.
10.1101/2020.09.22.309211 — genomics — Posted on 2020-09-24
890 Etv5 is not required for Schwann cell development but is required to regulate the Schwann cell response to peripheral nerve injury
Balakrishnan, A.; Belfiore, L.; Vasan, L.; Touahri, Y.; Stykel, M.; Fleming, T.; Midha, R.; Biernaskie, J.; Schuurmans, C.
10.1101/2020.09.23.309815 — developmental biology — Posted on 2020-09-24
894 TopoStats - an automated tracing program for AFM images
Beton, J. G.; Helfmann, L.; Gray, R.; Hoogenboom, B.; Joseph, A. P.; Topf, M.; Pyne, A. L. B.
10.1101/2020.09.23.309609 — biophysics — Posted on 2020-09-24
896 Natrix: A Snakemake-based workflow for processing, clustering, and taxonomically assigning amplicon sequencing reads
Welzel, M.; Lange, A.; Heider, D.; Schwarz, P. M.; Freisleben, B.; Jensen, M.; Boenigk, J.; Beisser, D.
10.1101/2020.09.23.309864 — bioinformatics — Posted on 2020-09-24
897 Nature-inspired Circular-economy Recycling (NaCRe) for Proteins: Proof of Concept
Stellacci, F.; Maerkl, S. J.; Mezzenga, R.; Giaveri, S.; Murello, A.; Roset Julia, L.; Ortiz, D.; Menin, L.; Patiny, L.; Schmitt, A. M.; Bolisetty, S.
10.1101/2020.09.23.309799 — biochemistry — Posted on 2020-09-24
899 An evolutionary portrait of the progenitor SARS-CoV-2 and its dominant offshoots in COVID-19 pandemic
Kumar, S.; Tao, Q.; Weaver, S.; Sanderford, M. D.; Caraballo, M.; Sharma, S.; Kosakovsky Pond, S. L.; Miura, S.
10.1101/2020.09.24.311845 — evolutionary biology — Posted on 2020-09-24
900 Resveratrol And Pterostilbene Potently Inhibit SARS-CoV-2 Infection In Vitro
ter Ellen, B. M.; Dinesh Kumar, N.; Bouma, E. M.; Troost, B.; van de Pol, D. P. I.; van der Ende-Metselaar, H. H.; Apperloo, L.; van Gosliga, D.; van den Berge, M.; Nawijn, M. C.; van der Voort, P. H. J.; Moser, J.; Rodenhuis-Zybert, I. A.; Smit, J. M.
10.1101/2020.09.24.285940 — microbiology — Posted on 2020-09-24
901 Hamster and ferret experimental infection with intranasal low dose of a single strain of SARS-CoV-2
Monchatre-Leroy, E.; Lesellier, S.; Wasniewski, M.; Picard-Meyer, E.; Richomme, C.; Boue, F.; Lacote, S.; Murri, S.; Pulido, C.; Vulin, J.; Salguero, F. J.; Legouilh, M. A.; Servat, A.; Marianneau, P.
10.1101/2020.09.24.311977 — microbiology — Posted on 2020-09-24
902 S-Trimer, a COVID-19 subunit vaccine candidate, induces protective immunity in nonhuman primates
Liang, J. G.; Su, D.; Song, T.-Z.; Zeng, Y.; Huang, W.; Wu, J.; Xu, R.; Luo, P.; Yang, X.; Zhang, X.; Luo, S.; Liang, Y.; Li, X.; Huang, J.; Wang, Q.; Huang, X.; Xu, Q.; Luo, M.; Huang, A.; Luo, D.; Zhao, C.; Yang, F.; Han, J.-B.; Zheng, Y.-T.; Liang, P.
10.1101/2020.09.24.311027 — immunology — Posted on 2020-09-24
905 A Brain Imaging-Based Deep Learning Classifier for Sex and Alzheimer's Disease
Lu, B.; Li, H.-X.; Chang, Z.-K.; Li, L.; Chen, N.-X.; Zhu, Z.-C.; Zhou, H.-X.; Fan, Z.; Yang, H.; Chen, X.; Yan, C.-G.
10.1101/2020.08.18.256594 — neuroscience — Posted on 2020-09-24
906 Gene Loss and Evolution of the Plastome
Mohanta, T. K.; Khan, A.; Hashem, A.; Abd_Allah, E. F.; Al-Harrasi, A.
10.1101/676304 — plant biology — Posted on 2020-09-24
907 Human inbreeding has decreased in time through the Holocene
Ceballos, F. C.; Gurun, K.; Altinisik, N. E.; Gemici, H. C.; Karamurat, C.; Koptekin, D.; Vural, K. B.; Surer, E.; Erdal, Y. S.; Gotherstrom, A.; Ozer, F.; Atakuman, C.; Somel, M.
10.1101/2020.09.24.311597 — genomics — Posted on 2020-09-24
908 Neural correlates of auditory pattern learning in the auditory cortex
Kang, H.; Auksztulewicz, R.; An, H.; Abichacra, N.; Sutter, M. L.; Schnupp, J. W. H.
10.1101/2020.09.24.311464 — neuroscience — Posted on 2020-09-24
910 Early alterations of large-scale brain networkstemporal dynamics in young children with autism.
Bochet, A.; Sperdin, H. F.; Rihs, T. A.; Kojovic, N.; Franchini, M.; Jan, R. K.; Michel, C. M.; Schaer, M.
10.1101/2020.09.24.311423 — neuroscience — Posted on 2020-09-24
911 Functional characterization of SARS-CoV-2 infection suggests a complex inflammatory response and metabolic alterations
Trilla-Fuertes, L.; Ramos-Ruiz, R.; Blanca-Lopez, N.; Lopez-Camacho, E.; Martin-Pedraza, L.; Ryan Murua, P.; Diaz-Almiron, M.; Llorens, C.; Gabaldon, T.; Moya, A.; Fresno, J. A.; Gamez-Pozo, A.
10.1101/2020.06.22.164384 — microbiology — Posted on 2020-09-24
912 Low replication stress leads to specific replication timing advances associated to chromatin remodelling in cancer cells
Courtot, L.; Bournique, E.; Maric, C.; Guitton-Sert, L.; Madrid-Mencia, M.; Pancaldi, V.; Cadoret, J.-C.; Hoffmann, J.-S.; Bergoglio, V.
10.1101/2020.08.19.256883 — cancer biology — Posted on 2020-09-24
913 Prime editing for functional repair in patient-derived disease models
Schene, I. F.; Joore, I. P.; Oka, R.; Mokry, M.; van Vugt, A. H. M.; van Boxtel, R.; van der Doef, H. P. J.; van der Laan, L. J. W.; Verstegen, M. M. A.; van Hasselt, P. M.; Nieuwenhuis, E. E. S.; Fuchs, S. A.
10.1101/2020.06.09.139782 — genomics — Posted on 2020-09-24
914 High-Resolution, Large Field-of-View, and Multi-View Single Objective Light-Sheet Microscopy
Yang, B.; Millett-Sikking, A.; Lange, M.; Can Solak, A.; Kobayashi, H.; York, A.; Royer, L. A.
10.1101/2020.09.22.309229 — developmental biology — Posted on 2020-09-24
915 The rise and the fall of a Pseudomonas aeruginosa epidemic lineage in a hospital
Petitjean, M.; Juarez, P.; Meunier, A.; daguindau, e.; Puja, H. n.; Bertrand, X.; Valot, B.; Hocquet, D.
10.1101/2020.09.21.307538 — microbiology — Posted on 2020-09-24
917 A potent synthetic nanobody targets RBD and protects mice from SARS-CoV-2 infection
Li, D.; Li, T.; Cai, H.; Yao, H.; Zhou, B.; Zhao, Y.; Qin, W.; Hutter, C. A. J.; Lai, Y.; Bao, J.; Lan, J.; Wong, G.; Seeger, M.; Lavillette, D.; Zhang, N.; Gong, Y.; Shen, Q.; Kuo, S.-M.; Bi, Y.
10.1101/2020.06.09.143438 — biochemistry — Posted on 2020-09-24
919 The dynamics of spawning acts by a semelparous fish and its associated energetic expenses
Tentelier, C.; Bouchard, C.; Bernardin, A.; Tauzin, A.; Aymes, J.-C.; Lange, F.; Recapet, C.; Rives, J.
10.1101/436295 — ecology — Posted on 2020-09-24
926 Smart Film Impacts Stomatal Sensitivity of Greenhouse Capsicum Through Altered Light
Zhao, C.; Chavan, S.; He, X.; Zhou, M.; Cazzonelli, C. I.; Chen, Z.-H. I.; Tissue, D. T.; Ghannoum, O.
10.1101/2020.09.22.309427 — plant biology — Posted on 2020-09-24
928 Molecular characterization of triple negative breast cancer formaldehyde-fixed paraffin-embedded samples by data independent acquisition proteomics
Garcia-Adrian, S.; Trilla-Fuertes, L.; Gamez-Pozo, A.; Chiva, C.; Lopez-Vacas, R.; Lopez-Camacho, E.; Prado-Vazquez, G.; Zapater-Moros, A.; Lumbreras-Herrera, M. I.; Hardisson, D.; Yebenes, L.; Zamora, P.; Sabido, E.; Fresno Vara, J. A.; Espinosa, E.
10.1101/2020.09.21.306654 — cancer biology — Posted on 2020-09-24
931 HIF1a-dependent induction of the mitochondrial chaperone TRAP1 regulates bioenergetic adaptations to hypoxia
Rasola, A.; Laquatra, C.; Sanchez-Martin, C.; Minervini, G.; Moroni, E.; Schiavone, M.; Tosatto, S. C. E.; Argenton, F.; Colombo, G.; Bernardi, P.; Masgras, I.
10.1101/2020.09.23.309450 — biochemistry — Posted on 2020-09-24
933 Structure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation target
Sobala, L. F.; Fernandes, P. Z.; Hakki, Z.; Thompson, A. J.; Howe, J. D.; Hill, M.; Zitzmann, N.; Davies, S.; Stamataki, Z.; Butters, T. D.; Alonzi, D. S.; Williams, S. J.; Davies, G. J.
10.1101/2020.06.30.179523 — biochemistry — Posted on 2020-09-24
935 Negative short-range genomic autocorrelation of causal effects on human complex traits
Schoech, A. P.; Weissbrod, O.; O'Connor, L. J.; Patterson, N.; Shi, H.; Reshef, Y.; Price, A.
10.1101/2020.09.23.310748 — genetics — Posted on 2020-09-24
936 Human Papillomavirus Type 16 L1/L2 VLP Experimental Internalization by Human Peripheral Blood Leukocytes
Cianciarullo, A. M.; Szulczewski, V.; Kavati, E. A.; Hosoda, T. M.; Leao, E.; Borelli, P.; Boccardo, E.; Mueller, M.; Karanam, B.; Becak, W.
10.1101/299214 — cell biology — Posted on 2020-09-24
938 Ancestry Inference Using Reference Labeled Clusters of Haplotypes
Noto, K.; Wang, Y.; Song, S.; Schraiber, J. G.; Sedghifar, A.; Byrnes, J. K.; Turissini, D. A.; Hong, E. L.; Ball, C. A.
10.1101/2020.09.23.310698 — genomics — Posted on 2020-09-24
942 Glycine acylation and trafficking of a new class of bacterial lipoprotein by a composite secretion system
Icke, C.; Hodges, F.; Pullela, K.; McKeand, S.; Bryant, J. A.; Cunningham, A. F.; Cole, J.; Henderson, I.
10.1101/2020.09.23.310854 — microbiology — Posted on 2020-09-24
943 T cells limit accumulation of aggregate pathology following intrastriatal injection of α-synuclein fibrils
George, S.; Tyson, T.; Rey, N. L.; Sheridan, R.; Peelaerts, W.; Becker, K.; Schulz, E.; Meyerdirk, L.; Burmeister, A.; Steiner, J.; Escobar, M. L.; Ma, J.; Pospisilik, A.; Labrie, V.; Brundin, L.; Brundin, P.
10.1101/2020.02.20.956599 — neuroscience — Posted on 2020-09-24
944 Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following demyelination
Saraswat, D.; Shayya, H. J.; Polanco, J. J.; Tripathi, A.; Welliver, R.; Pol, S. U.; Seidman, R. A.; Broome, J. E.; O'Bara, M. A.; van Kuppervelt, T. H.; Phillips, J. J.; Dutta, R.; Sim, F. J.
10.1101/2020.01.21.906073 — neuroscience — Posted on 2020-09-24
946 SpRY greatly expands the genome editing scope in rice with highly flexible PAM recognition
Xu, Z.; Kuang, Y.; Ren, B.; Yan, D.; Yan, F.; Spetz, C.; Sun, W.; Wang, G.; Zhou, X.; Zhou, H.
10.1101/2020.09.23.310839 — plant biology — Posted on 2020-09-24
949 scFEA: A graph neural network model to estimate cell-wise metabolic flux using single cell RNA-seq data
Alghamdi, N.; Chang, W.; Dang, P.; Lu, X.; Wan, C.; Huang, Z.; Wang, J.; Fishel, M. L.; Cao, S.; Zhang, C.
10.1101/2020.09.23.310656 — bioinformatics — Posted on 2020-09-24
950 Structural biologists, lets mind our colors
Saladi, S. M.; Maggiolo, A. O.; Radford, K.; Clemons, W. M.
10.1101/2020.09.22.308593 — biochemistry — Posted on 2020-09-24
951 Deep learning and alignment of spatially-resolved whole transcriptomes of single cells in the mouse brain with Tangram
Biancalani, T.; Scalia, G.; Buffoni, L.; Avasthi, R.; Lu, Z.; Sanger, A.; Tokcan, N.; Vanderburg, C. R.; Segerstolpe, A.; Zhang, M.; Avraham-Davidi, I.; Vickovic, S.; Nitzan, M.; Ma, S.; Buenrostro, J. D.; Brown, N. B.; Fanelli, D.; Zhuang, X.; Macosko, E.; Regev, A.
10.1101/2020.08.29.272831 — genomics — Posted on 2020-09-24
952 High performance machine learning models can fully automate labeling of camera trap images for ecological analyses
Whytock, R. C.; Swiezewski, J.; Zwerts, J. A.; Bara-Słupski, T.; Koumba Pambo, A. F.; Rogala, M.; Bahaa-el-din, L.; Boekee, K.; Brittain, S.; Cardoso, A. W.; Henschel, P.; Lehmann, D.; Momboua, B.; Opepa, C. K.; Orbell, C.; Pitman, R. T.; Robinson, H. S.; Abernethy, K. A.
10.1101/2020.09.12.294538 — ecology — Posted on 2020-09-24
954 The Clostridioides difficile species problem: global phylogenomic analysis uncovers three ancient, toxigenic, genomospecies
Knight, D. R.; Imwattana, K.; Kullin, B.; Guerrero-Araya, E.; Paredes-Sabja, D.; Didelot, X.; Dingle, K. E.; Eyre, D. W.; Rodriguez, C.; Riley, T. V.
10.1101/2020.09.21.307223 — microbiology — Posted on 2020-09-24
955 MDA5 is an essential vita-PAMP sensor necessary for host resistance against Aspergillus fumigatus
Wang, X.; Caffrey-Carr, A. K.; Liu, K.-w.; Espinosa, V.; Croteau, W.; Dhingra, S.; Rivera, A.; Cramer, R. A.; Obar, J. J.
10.1101/2020.07.06.182154 — immunology — Posted on 2020-09-24
958 Chronic stress induces sex-specific functional and morphological alterations in cortico-accumbal and cortico-tegmental pathways
Bittar, T. P.; Pelaez, M. C.; Hernandez Silva, J. C.; Quessy, F.; Lavigne, A.-A.; Morency, D.; Blanchette, L.-J.; Arsenault, E.; Cherasse, Y.; Seigneur, J.; Timofeev, I.; Sephton, C. F.; Proulx, C. D.; Labonte, B.
10.1101/2020.09.22.306860 — neuroscience — Posted on 2020-09-24
960 Parallel processing of sensory cue and spatial information in the Dentate Gyrus
Tuncdemir, S. N.; Grosmark, A. D.; Turi, G.; Shank, A.; Bowler, J.; Ordek, G.; Losonczy, A.; Hen, R.; Lacefield, C. O.
10.1101/2020.02.13.947903 — neuroscience — Posted on 2020-09-24
964 Insufficient Eye Tracking Data Leads to Errors in Evaluating Typical and Atypical Fixation Preferences
Reimann, G. E.; Walsh, C.; Csumitta, K.; McClure, P.; Pereira, F.; Martin, A.; Ramot, M.
10.1101/2020.09.21.306621 — neuroscience — Posted on 2020-09-24
965 SFRP1 shapes astrocyte to microglia cross-talk in acute and chronic neuroinflammation
Rueda-Carrasco, J.; Mateo, M. I.; Borroto, A.; Martin-Bermejo, M. J.; Kummer, M. P.; Schwartz, S.; Lopez-Atalaya, J. P.; Alarcon, B.; Heneka, M. T.; Esteve, P.; Bovolenta, P.
10.1101/2020.03.10.982579 — neuroscience — Posted on 2020-09-24
968 Pharmacological prevention of neonatal opioid withdrawal in a pregnant guinea pig model.
Safa, A.; Lau, A. R.; Aten, S.; Schilling, K.; Bales, K. L.; Miller, V. A.; Fitzgerald, J.; Chen, M.; Hill, K.; Dzwigalski, K.; Obrietan, K.; Phelps, M. A.; Sadee, W.; Oberdick, J.
10.1101/2020.07.25.221192 — pharmacology and toxicology — Posted on 2020-09-24
971 Laser-activated drug implant for controlled release to the posterior segment of the eye
He, X.; Yuan, Z.; Gaeke, S.; Kao, W. W.; Miller, D.; Williams, B.; Li, S. K.; Park, Y.
10.1101/2020.06.17.111641 — bioengineering — Posted on 2020-09-24
972 High-density Neural Recordings from Feline Sacral Dorsal Root Ganglia with Thin-film Array
Sperry, Z. J.; Na, K.; Jun, J.; Madden, L. R.; Socha, A.; Yoon, E.; Seymour, J. P.; Bruns, T. M.
10.1101/2020.07.14.199653 — bioengineering — Posted on 2020-09-24
973 Tyrosine-Derived Polycarbonate Nerve Guidance Tubes Elicit Pro-Regenerative Extracellular Matrix Deposition When Used to Bridge Segmental Nerve Defects in Swine
Burrell, J. C.; Bhatnagar, D.; Brown, D. P.; Murthy, N. S.; Dutton, J.; Laimo, F. A.; Ali, Z.; Rosen, J. M.; Kaplan, H. M.; Kohn, J.; Cullen, D. K.
10.1101/2020.01.11.902007 — bioengineering — Posted on 2020-09-24
975 Regulation of protein abundance in genetically diverse mouse populations
Keele, G. R.; Zhang, T.; Pham, D. T.; Vincent, M.; Bell, T. A.; Hock, P.; Shaw, G. D.; Munger, S. C.; de Villena, F. P.-M.; Ferris, M. T.; Gygi, S. P.; Churchill, G. A.
10.1101/2020.09.18.296657 — genomics — Posted on 2020-09-24
976 Rad21l1 cohesin subunit is dispensable for spermatogenesis but not oogenesis in zebrafish
Blokhina, Y. P.; Frees, M. A.; Nguyen, A.; Sharifi, M.; Chu, D. B.; Draper, B. W.; Burgess, S. M.
10.1101/2020.09.23.309591 — genetics — Posted on 2020-09-23
978 rec-Y2H matrix screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins
Lang, B.; Yang, J.-S.; Garriga-Canut, M.; Speroni, S.; Gili, M.; Hoffmann, T.; Tartaglia, G. G.; Maurer, S. P.
10.1101/2020.09.14.296160 — cell biology — Posted on 2020-09-24
981 Temperature-dependent fasciation mutants connect mitochondrial RNA processing to the control of cell proliferation during lateral root morphogenesis
Otsuka, K.; Mamiya, A.; Konishi, M.; Nozaki, M.; Kinoshita, A.; Tamaki, H.; Arita, M.; Saito, M.; Yamamoto, K.; Hachiya, T.; Noguchi, K.; Ueda, T.; Yagi, Y.; Kobayashi, T.; Nakamura, T.; Sato, Y.; Hirayama, T.; Sugiyama, M.
10.1101/2020.06.09.141382 — plant biology — Posted on 2020-09-23
982 RNA-bound PGC-1α controls gene expression in liquid-like nuclear condensates
Perez-Schindler, J.; Kohl, B.; Schneider-Heieck, K.; Adak, V.; Delezie, J.; Maier, G.; Sakoparnig, T.; Vargas-Fernandez, E.; Karrer-Cardel, B.; Ritz, D.; Schmidt, A.; Hondele, M.; Hiller, S.; Handschin, C.
10.1101/2020.09.23.310623 — molecular biology — Posted on 2020-09-23
983 An interbacterial DNA deaminase toxin directly mutagenizes surviving target populations
de Moraes, M. H.; Hsu, F.; Huang, D.; Bosch, D. E.; Zeng, J.; Radey, M. C.; Simon, N.; Ledvina, H. E.; Frick, J. P.; Wiggins, P. A.; Peterson, S. B.; Mougous, J. D.
10.1101/2020.09.23.270603 — microbiology — Posted on 2020-09-23
984 CD8 coreceptor-mediated focusing can reorder the agonist hierarchy of peptide ligands recognized via the T cell receptor
Clement, M.; Knezevic, L.; Dockree, T.; McLaren, J. E.; Ladell, K.; Miners, K.; Llewellyn-Lacey, S.; Francis, O.; Sewell, A. K.; Bridgeman, J. S.; Price, D. A.; van den Berg, H. A.; Wooldridge, L.
10.1101/2020.09.23.310375 — immunology — Posted on 2020-09-23
985 Eye-head coordination and dynamic visual scanning as indicators of visuo-cognitive demands in driving simulator
Mikula, L.; Mejia-Romero, S.; Chaumillon, R.; Patoine, A.; Lugo, E.; Bernardin, D.; Jocelyn, F.
10.1101/2020.09.23.309559 — neuroscience — Posted on 2020-09-23
989 Resolving atomic site interactions of the Y. pestis outer membrane protein Ail with human serum in the bacterial cell envelope
Kent, J. E.; Fujimoto, L. M.; Shn, K.; Singh, C.; Yao, Y.; Park, S.; Opella, S. J.; Plano, G. V.; Marassi, F. M.
10.1101/2020.09.23.310672 — biochemistry — Posted on 2020-09-23
990 Germline DNA replication shapes the recombination landscape in mammals
Pratto, F.; Brick, K.; Cheng, G.; Lam, K.-W. G.; Cloutier, J. M.; Dahiya, D.; Wellard, S. R.; Jordan, P. W.; Camerini-Otero, R. D.
10.1101/2020.09.23.308874 — genomics — Posted on 2020-09-23
991 Transposable element control disrupted by meiotic drive in a stalk-eyed fly genome
Reinhardt, J. A.; Baker, R. H.; Zimin, A. V.; Ladias, C.; Paczolt, K.; Werren, J.; Hayashi, C.; Wilkinson, G. S.
10.1101/2020.09.23.310227 — evolutionary biology — Posted on 2020-09-23
993 A phospho-regulated ensemble signal motif of α-TAT1 drives dynamic microtubule acetylation
Inoue, T.; Deb Roy, A.; Gross, E.; Pillai, G.; Seetharaman, S.; Etienne-Manneville, S.
10.1101/2020.09.23.310235 — cell biology — Posted on 2020-09-23
998 Rickettsia parkeri Sca2 promotes dissemination in an intradermal infection mouse model
Burke, T. P.; Tran, C. J.; Engstrom, P.; Glasner, D. R.; Espinosa, D. A.; Harris, E.; Welch, M. D.
10.1101/2020.09.23.310409 — microbiology — Posted on 2020-09-23
999 Generating Artificial Sensations with Spinal Cord Stimulation in Primates and Rodents
Yadav, A. P.; Li, S.; Krucoff, M. O.; Lebedev, M. A.; Abd-El-Barr, M. M.; Nicolelis, M. A. L.
10.1101/2020.05.09.085647 — neuroscience — Posted on 2020-09-23
1001 Lisen&Curate: A platform to facilitate knowledge tools for curation of regulation of transcription initiation in bacteria
Mendez-Cruz, C.-F.; Diaz-Rodriguez, M.; Guadarrama-Garcia, F.; Lithgow-Serrano, O. W.; Gama-Castro, S.; Solano-Lira, H.; Rinaldi, F.; Collado-Vides, J.
10.1101/2020.04.28.065243 — bioinformatics — Posted on 2020-09-23
1002 A rapid and simple method for assessing and representing genome sequences relatedness
Briand, M.; Bouzid, M.; Hunault, G.; Legeay, M.; Fischer-Le Saux, M.; Barret, M.
10.1101/569640 — genomics — Posted on 2020-09-23
1003 Sex-specific effects of in vitro fertilization on adult metabolic phenotypes and hepatic transcriptomic and proteomic pathways in mouse.
Bartolomei, M. S.; Narapareddy, L.; Schultz, R. M.; Garcia, B. A.; Rhon-Calderon, E.; Vrooman, L. A.; Nguyen, D.; Baeza, J.; Lan, Y.
10.1101/2020.09.23.309989 — developmental biology — Posted on 2020-09-23
1004 Mechanism of cell polarisation and first lineage segregation in the human embryo
Zhu, M.; Shahbazi, M. N.; Martin, A.; Zhang, C.; Sozen, B.; Borsos, M.; Mandelbaum, R. S.; Paulson, R. J.; Mole, M. A.; Esbert, M.; Scott, R. T.; Campbell, A.; Fishel, S.; Gradinaru, V.; Zhao, H.; Wu, K.; Chen, Z.; Seli, E.; de los Santos, M. J.; Zernicka-Goetz, M.
10.1101/2020.09.23.310680 — developmental biology — Posted on 2020-09-23
1005 Tuning TPO-R signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemia
Cui, L.; Moraga, I.; Lerbs, T.; Neste, C. V.; Wilmes, S.; Tsutsumi, N.; Trotman-Grant, A. C.; Gakovic, M.; Andrews, S.; Gotlib, J.; Darmanis, S.; Enge, M.; Quake, S.; Hitchcock, I. S.; Piehler, J.; Garcia, C.; Wernig, G.
10.1101/2020.09.23.290593 — cell biology — Posted on 2020-09-23
1006 A novel Hsp90 phospho-switch modulates virulence in the major human fungal pathogen Candida albicans
Diezmann, S.; Alaalm, L.; Crunden, J. L.; Butcher, M.; Obst, U.; Whealy, R.; Williamson, C. E.; O'Brien, H. E.; Schaffitzel, C.; Ramage, G.
10.1101/2020.09.23.309831 — microbiology — Posted on 2020-09-23
1009 PspA maintains membrane integrity by an ESCRT-like membrane remodeling activity
Junglas, B.; Huber, S. T.; Heidler, T.; Mann, D.; Hennig, R.; Clarke, M.; Ortiz, J. O.; Schneider, D.; Sachse, C.
10.1101/2020.09.23.309765 — microbiology — Posted on 2020-09-23
1010 A proof of concept for neutralizing antibody-guided vaccine design against SARS-CoV-2
Zhang, L.; Cao, L.; Gao, X.; Zheng, B.; Deng, Y.; Li, J.-X.; Feng, R.; Bian, Q.; Guo, X.-L.; Wang, N.; Qiu, H.-Y.; Wang, L.; Cui, Z.; Ye, Q.; Chen, G.; Lu, K.-K.; Chen, Y.; Chen, Y.-T.; Pan, H.-X.; Zhu, B.-L.; Qin, C.-F.; Wang, X.; Zhu, F.-C.
10.1101/2020.09.23.309294 — microbiology — Posted on 2020-09-23
1011 Establishment of a reverse genetics system for SARS-CoV-2 using circular polymerase extension reaction
Torii, S.; Ono, C.; Suzuki, R.; Morioka, Y.; Anzai, I.; Fauzyah, Y.; Maeda, Y.; Kamitani, W.; Fukuhara, T.; Matsuura, Y.
10.1101/2020.09.23.309849 — microbiology — Posted on 2020-09-23
1012 Respiratory disease in cats associated with human-to-cat transmission of SARS-CoV-2 in the UK
Hosie, M. J.; Epifano, I.; Herder, V.; Orton, R.; Stevenson, A.; Johnson, N.; MacDonald, E.; Dunbar, D.; McDonald, M.; Howie, F.; Tennant, B.; Herrity, D.; Filipe, A. C.; Streicker, D. G.; Willett, B. J.; Murcia, P. R.; Jarrett, R. F.; Robertson, D. L.; Weir, W.; COVID-19 Genomics UK Consortium,
10.1101/2020.09.23.309948 — microbiology — Posted on 2020-09-23
1013 Cross-reactive serum and memory B cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection
Song, G.; He, W.-t.; Callaghan, S.; Anzanello, F.; Huang, D.; Ricketts, J.; Torres, J. L.; Beutler, N.; Peng, L.; Vargas, S.; Cassell, J.; Parren, M.; Yang, L.; Ignacio, C.; Smith, D. M.; Voss, J. E.; Nemazee, D.; Ward, A. B.; Rogers, T.; Burton, D. R.; Andrabi, R.
10.1101/2020.09.22.308965 — immunology — Posted on 2020-09-23
1015 The COVID-19 PHARMACOME: Rational Selection of Drug Repurposing Candidates from Multimodal Knowledge Harmonization
Schultz, B. T.; Zaliani, A.; Ebeling, C.; Reinshagen, J.; Bojkova, D.; Lage-Rupprecht, V.; Karki, R.; Lukassen, S.; Gadiya, Y.; Ravindra, N. G.; Das, S.; Baksi, S.; Domingo-Fernandez, D.; Lentzen, M.; Strivens, M.; Raschka, T.; Cinatl, J.; DeLong, L.; Gribbon, P.; Geisslinger, G.; Ciesek, S.; van Dijk, D.; Gardner, S.; Tom Kodamullil, A.; Froehlich, H.; Peitsch, M.; Jacobs, M.; Hoeng, J.; Eils, R.; Claussen, C.; Hofmann-Apitius, M.
10.1101/2020.09.23.308239 — bioinformatics — Posted on 2020-09-23
1017 Lytic bacteriophages facilitate antibiotic sensitization of Enterococcus faecium
Canfield, G. S.; Chatterjee, A.; Mangalea, M. R.; Sheriff, E. K.; Keidan, M.; McBride, S. W.; McCollister, B. D.; Duerkop, B. A.
10.1101/2020.09.22.309401 — microbiology — Posted on 2020-09-23
1019 Clinical interpretation of integrative molecular profiles to guide precision cancer medicine
Reardon, B.; Moore, N. D.; Moore, N.; Kofman, E.; Aldubayan, S.; Cheung, A.; Conway, J.; Elmarakeby, H.; Imamovic, A.; Kamran, S. C.; Keenan, T.; Keliher, D.; Konieczkowski, D. J.; Liu, D.; Mouw, K.; Park, J.; Vokes, N.; Dietlein, F.; Van Allen, E. M.
10.1101/2020.09.22.308833 — cancer biology — Posted on 2020-09-23
1028 Type I interferon potentiates metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice
Lei, Y.; Martinez, C. G.; Torres-Odio, S.; Bell, S. L.; Birdwell, C. E.; Bryant, J. D.; Tong, C. W.; Watson, R. O.; West, L. C.; West, A. P.
10.1101/2020.09.22.308171 — immunology — Posted on 2020-09-23
1029 Ex vivo Demonstration of Functional Deficiencies in Popliteal Lymphatic Vessels from TNF-Tg Mice with Inflammatory Arthritis
Scallan, J. P.; Bouta, E. M.; Rahimi, H.; Kenney, H. M.; Ritchlin, C. T.; Davis, M. J.; Schwarz, E. M.
10.1101/2020.09.22.309070 — pathology — Posted on 2020-09-23
1030 Enhanced functionality of low-affinity CD19 CAR T-cells is associated with activation priming and a polyfunctional cytokine phenotype
Michelozzi, I. M.; Gomez-Castaneda, E.; Pohle, R. V. C.; Cardoso-Rodriguez, F.; Sufi, J.; Puigdevall-Costa, P.; Subraniyam, M.; Wu, S. W.; Guvenel, A.; Ghorashian, S.; Pule, M. A.; Tape, C. J.; Castellano, S.; Amrolia, P. J.; Giustacchini, A.
10.1101/2020.09.22.291831 — cancer biology — Posted on 2020-09-23
1031 Breast tumors escape endocrine therapy by ER-independent mechanisms triggered by the coordinated activities of HER2/HER3 and deacetylated FOXA1
Gilfillan, S.; Wang, S.; Katika, M. R.; Norum, J. H.; Bergholtz, H.; Fiorito, E.; Nordhagen, S.; Sharma, Y.; Singh, S.; Somisety, V. S.; Fosdahl, A.-M.; Nord, S.; Engebraaten, O.; Lingjaerde, O. C.; Borresen-Dale, A.-L.; Sahlberg, K. K.; Sorlie, T.; Bellet, M.; Lopez-Aviles, S.; Hurtado-Rodriguez, A.
10.1101/2020.09.22.308569 — cancer biology — Posted on 2020-09-23
1034 Establishment of multiple novel patient-derived models of desmoplastic small round cell tumor enabling functional characterization of ERBB pathway signaling and pre-clinical evaluation of a novel targeted therapy approach
Smith, R. S.; Odintsov, I.; Liu, Z.; Hayashi, T.; Lui, A. J. W.; Vojnic, M.; Suehara, Y.; Mattar, M. S.; Hmeljak, J.; Ramirez, H. A.; Shaw, M.; Bui, G.; Hartono, A. B.; Gladstone, E.; Magnan, H.; Khodos, I.; de Stanchina, E.; La Quaglia, M. P.; Yao, J.; Lae, M.; Lee, S. B.; Spraggon, L.; Pratilas, C. A.; Ladanyi, M.; Somwar, R.
10.1101/2020.09.22.308940 — cancer biology — Posted on 2020-09-23
1036 Habitat differences filter functional diversity of low dispersive microscopic animals
Martinez, A.; Garcia-Gomez, G.; Garcia-Herrero, A.; Sanchez, N.; Pardos, F.; Izquierdo-Munoz, A.; Fontaneto, D.; Mammola, S.
10.1101/2020.09.22.308353 — ecology — Posted on 2020-09-23
1037 Outer membrane lipoprotein DolP interacts with the BAM complex and promotes fitness during envelope stress response
Ranava, D.; Yang, Y.; Orenday-Tapia, L.; Rousset, F.; Turlan, C.; Cui, L.; Morales, V.; Moulin, C.; Munoz, G.; Rech, J.; Caumont-Sarcos, A.; Albenne, C.; Bikard, D.; Ieva, R.
10.1101/2020.09.23.308296 — microbiology — Posted on 2020-09-23
1039 Intercontinental prediction of soybean phenology via hybrid ensemble of knowledge-based and data-driven models
McCormick, R. F.; Truong, S. K.; Rotundo, J.; Gaspar, A. P.; Kyle, D.; van Eeuwijk, F.; Messina, C. D.
10.1101/2020.09.22.306506 — plant biology — Posted on 2020-09-23
1041 First high-quality reference genome of Amphicarpaea edgeworthii
Song, T.; Zhou, M.; Yuan, Y.; Yu, J.; Cai, H.; Li, J.; Chen, Y.; Bai, Y.; Zhou, G.; Cui, G.
10.1101/2020.09.22.306811 — genomics — Posted on 2020-09-23
1042 Dual symbiosis in the deep-sea hydrothermal vent snail Gigantopelta aegis revealed by its hologenome
Lan, Y.; Sun, J.; Chen, C.; Sun, Y.; Zhou, Y.; YANG, Y.; Zhang, W.; Li, R.; Zhou, K.; Wong, W. C.; Kwan, Y. H.; Cheng, A.; Bougouffa, S.; Van Dover, C. L.; Qiu, J.-W.; Qian, P.-Y.
10.1101/2020.09.23.308304 — genomics — Posted on 2020-09-23
1051 Synaptic silencing affects the density and complexity of oligodendrocyte precursor cells in the adult mouse hippocampus
Chacon-de-la-Rocha, I.; Fryatt, G.; Rivera, A.; Restani, L.; Caleo, M.; Raineteau, O.; Gomez-Nicola, D.; Butt, A. M.
10.1101/2020.09.23.309682 — neuroscience — Posted on 2020-09-23
1057 SSMD: A semi-supervised approach for a robust cell type identification and deconvolution of mouse transcriptomics data
Lu, X.; Tu, S.-W.; Chang, W.; Wan, C.; Wang, J.; Zang, Y.; Ramdas, B.; Kapur, R.; Lu, X.; Cao, S.; Zhang, C.
10.1101/2020.09.22.309278 — bioinformatics — Posted on 2020-09-23
1060 Accelerated dystrophy and decay of oligodendrocyte precursor cells in the APP/PS1 model of Alzheimer's-like pathology
Chacon-de-la-Rocha, I.; Fryatt, G.; Rivera, A. D.; Verkhratsky, A.; Raineteau, O.; Gomez-Nicola, D. M.; Butt, A. M.
10.1101/2020.09.23.309666 — neuroscience — Posted on 2020-09-23
1061 SFPQ intron retention, reduced expression and aggregate formation in central nervous system tissue are pathological features of amyotrophic lateral sclerosis
Hogan, A. L.; Grima, N.; Fifita, J. A.; McCann, E. P.; Heng, B.; Chan Moi Fat, S.; Maharjan, R.; Cain, A. K.; Henden, L.; Zang, K. Y.; Zhao, Q.; Zhang, Z.-H.; Wright, A.; Wu, S.; Morsch, M.; Yang, S.; Williams, K. L.; Blair, I. P.
10.1101/2020.09.22.309062 — neuroscience — Posted on 2020-09-23
1062 Higher-order sensorimotor circuit of the brain' global network supports human consciousness
Qin, P.; Wu, X.; Wu, C.; Wu, H.; Zhang, J.; Huang, Z.; Weng, X.; Qi, Z.; Tang, W.; Hiromi, T.; Tan, J.; Tanabe, S.; Fogel, S.; Hudetz, A. G.; Yang, Y.; Stamatakis, E. A.; Mao, Y.; Northoff, G.
10.1101/2020.09.22.308072 — neuroscience — Posted on 2020-09-23
1063 Eye and hand movements disrupt attentional control
Hanning, N. M.; Wollenberg, L.; Jonikaitis, D.; Deubel, H.
10.1101/2020.09.22.309237 — neuroscience — Posted on 2020-09-23
1067 Predicting species and community responses to global change in Australian mountain ecosystems using structured expert judgement
Camac, J. S.; Umbers, K.; Morgan, J. W.; Geange, S. R.; Hanea, A.; Slatyer, R.; McDougall, K.; Venn, S.; Vesk, P. A.; Hoffmann, A. A.; Nicotra, A. B.
10.1101/2020.09.23.309377 — ecology — Posted on 2020-09-23
1068 Maturation of the matrix and viral membrane of HIV-1
Qu, K.; Ke, Z.; Zila, V.; Anders-Osswein, M.; Glass, B.; Mueller, B.; Krausslich, H.-G.; Briggs, J. A. G.
10.1101/2020.09.23.309542 — microbiology — Posted on 2020-09-23
1069 The His-tag as a decoy modulating preferred orientation in cryoEM
Bromberg, R.; Guo, Y.; Plymire, D. A.; Emde, T.; Puzio, M.; Borek, D.; Otwinowski, Z.
10.1101/2020.09.22.309005 — biophysics — Posted on 2020-09-23
1071 Whole Exome Sequencing of a large family with Primary Open Angle Glaucoma reveals its vast complexity
Mohd, H. S.; Kumaran, M.; Abdul Kader, M.; R, R.; Subbiah., K. R.; Devarajan, B.; Periasamy, S.
10.1101/2020.09.21.306191 — genomics — Posted on 2020-09-23
1073 At each site its diversity: DNA barcoding reveals remarkable earthworm diversity in neotropical rainforests of French Guiana
Maggia, M.-E.; Decaëns, T.; Lapied, E.; Dupont, L.; Roy, V.; Schimann, H.; Orivel, J.; Murienne, J.; Baraloto, C.; Cottenie, K.; Steinke, D.
10.1101/2020.09.21.307348 — ecology — Posted on 2020-09-23
1074 Membrane binding controls ordered self-assembly of animal septins
Szuba, A.; Bano, F.; Iv, F.; Mavrakis, M.; Richter, R. P.; Bertin, A.; Koenderink, G. H.
10.1101/2020.09.22.307918 — cell biology — Posted on 2020-09-23
1076 Unraveling the interaction between doxorubicin and DNA origami nanostructures for customizable chemotherapeutic drug release
Ijäs, H.; Shen, B.; Heuer-Jungemann, A.; Keller, A.; Kostiainen, M. A.; Liedl, T.; Ihalainen, J. A.; Linko, V.
10.1101/2020.05.13.088054 — biochemistry — Posted on 2020-09-23
1077 The dynamics of spawning acts by a semelparous fish and its associated energetic expenses
Tentelier, C.; Bouchard, C.; Bernardin, A.; Tauzin, A.; Aymes, J.-C.; Lange, F.; Recapet, C.; Rives, J.
10.1101/436295 — ecology — Posted on 2020-09-23
1080 NeutrobodyPlex - Nanobodies to monitor a SARS-CoV-2 neutralizing immune response
Wagner, T.; Kaiser, P. D.; Gramlich, M.; Becker, M.; Traenkle, B.; Junker, D.; Haering, J.; Schweizer, H.; Nueske, S.; Scholz, A.; Zeck, A.; Schenke-Layland, K.; Nelde, A.; Strengert, M.; Krause, G.; Walz, J. S.; Ruetalo, N.; Schindler, M.; Schneiderhan-Marra, N.; Rothbauer, U.
10.1101/2020.09.22.308338 — immunology — Posted on 2020-09-23
1083 Gaze stabilisation behaviour is anisotropic across visual field locations in zebrafish
Dehmelt, F. A.; Meier, R.; Hinz, J.; Yoshimatsu, T.; Simacek, C. A.; Wang, K.; Baden, T. B.; Arrenberg, A. B.
10.1101/754408 — neuroscience — Posted on 2020-09-23
1085 Measurement Reliability for Individual Differences in Multilayer Network Dynamics: Cautions and Considerations
Yang, Z.; Telesford, Q. K.; Franco, A. R.; Lim, R.; Gu, S.; Xu, T.; Ai, L.; Castellanos, F. X.; Yan, C.-G.; Colcombe, S.; Milham, M. P.
10.1101/2020.01.24.914622 — neuroscience — Posted on 2020-09-23
1088 Single-molecule FRET dynamics of molecular motors in an ABEL Trap
Dienerowitz, M.; Howard, J. A. L.; Quinn, S. D.; Dienerowitz, F.; Leake, M. C.
10.1101/2020.09.21.306704 — biophysics — Posted on 2020-09-23
1089 An Advanced Framework for Time-lapse Microscopy Image Analysis
Jiang, Q.; Sudalagunta, P.; Meads, M. B.; Ahmed, K. T.; Rutkowski, T.; Shain, K.; Silva, A. S.; Zhang, W.
10.1101/2020.09.21.303800 — bioinformatics — Posted on 2020-09-23
1091 INTEGRINS MEDIATE PLACENTAL EXTRACELLULAR VESICLE TRAFFICKING TO LUNG AND LIVER IN VIVO
Nguyen, S. L.; Ahn, S. H.; Greenberg, J.; Collaer, B.; Agnew, D.; Arora, R.; Petroff, M.
10.1101/2020.09.22.309047 — cell biology — Posted on 2020-09-23
1093 Supplementation of a lacto-fermented rapeseed-seaweed blend promotes gut microbial- and gut immune-modulation in weaner piglets
Hui, Y.; Tamez-Hidalgo, P.; Cieplak, T.; Satessa, G. D.; Kot, W. P.; Soren, S. K.; Nielsen, M. O.; Nielsen, D. S.; Krych, L.
10.1101/2020.09.22.308106 — microbiology — Posted on 2020-09-23
1096 Transsynaptic mapping of Drosophila mushroom body output neurons
Scaplen, K. M.; Talay, M.; Fisher, J. D.; Cohn, R.; Sorkac, A.; Aso, Y.; Barnea, G.; Kaun, K. R.
10.1101/2020.09.22.309021 — neuroscience — Posted on 2020-09-23
1098 Influence of sensory modality and control dynamics on human path integration
Stavropoulos, A.; Lakshminarasimhan, K. J.; Laurens, J.; Pitkow, X.; Angelaki, D.
10.1101/2020.09.21.307256 — neuroscience — Posted on 2020-09-23
1104 A tale of two tails - efficient profiling of protein degraders by specific functional and target engagement readouts
Chernobrovkin, A. L.; Cazares-Korner, C.; Friman, T.; Caballero, I. M.; Amadio, D.; Martinez Molina, D.
10.1101/2020.09.22.307926 — molecular biology — Posted on 2020-09-23
1106 Discrete escape responses are generated by neuropeptide-mediated circuit logic
Imambocus, B. N.; Wittich, A.; Tenedini, F. M.; Zhou, F.; Hu, C.; Sauter, K.; Varela, E.; Heredia, F.; Casimiro, A. P.; Macedo, A.; Yang, C.-H.; Schlegel, P.; Pankratz, M. J.; Miguel-Aliaga, I.; Gontijo, A. M.; Cardona, A.; Soba, P.
10.1101/2020.09.22.307033 — neuroscience — Posted on 2020-09-22
1107 A comprehensive, FAIR file format for neuroanatomical structure modeling
Sullivan, A. E.; Tappan, S. J.; Angstman, P. J.; Rodriguez, A.; Thomas, G. C.; Hoppes, D. M.; Abdul-Karim, M.-A.; Heal, M. L.; Glaser, J. R.
10.1101/2020.09.22.306670 — neuroscience — Posted on 2020-09-22
1108 De novo DNA methylation controls neuronal maturation during adult hippocampal neurogenesis
Zocher, S.; Overall, R. W.; Berdugo-Vega, G.; Rund, N.; Karasinsky, A.; Adusumilli, V.; Steinhauer, C.; Scheibenstock, S.; Haendler, K.; Schultze, J. L.; Calegari, F.; Kempermann, G.
10.1101/2020.09.22.308692 — neuroscience — Posted on 2020-09-22
1109 Amyloid plaque deposition accelerates tau propagation via activation of microglia in a humanized APP mouse model
Clayton, K. A.; Delpech, J. C.; Herron, S.; Iwahara, N.; Saito, T.; Saido, T.; Ikezu, S.; Ikezu, T.
10.1101/2020.09.22.308015 — neuroscience — Posted on 2020-09-22
1110 Pioglitazone improves deficits of Fmr1-KO mouse model of Fragile X syndrome by interfering with excessive diacylglycerol signaling
Geoffroy, A.; Habbas, K.; Zambo, B.; Schramm, L.; Duchon, A.; Flatter, E.; Fouillen, L.; Zumsteg, J.; Heintz, D.; Mandel, J.-L.; Herault, Y.; Moine, H.
10.1101/2020.09.22.301762 — neuroscience — Posted on 2020-09-22
1115 DNA nanoswitch barcodes for multiplexed biomarker profiling
Chandrasekaran, A. R.; MacIsaac, M.; Vilcapoma, J.; Hansen, C. H.; Yang, D.; Wong, W. P.; Halvorsen, K.
10.1101/2020.09.22.309104 — bioengineering — Posted on 2020-09-22
1117 Actuation Enhances Patterning in Human Neural Tube Organoids
Fattah, A. R. A.; Daza, B.; Rustandi, G.; Berrocal-Rubio, M. A.; Gorissen, B.; Poovathingal, S.; Davie, K.; Cao, X.; Rosenzweig, D. H.; Lei, Y.; Finnell, R.; Verfaillie, C.; Sampaolesi, M.; Dedecker, P.; Van Oosterwyck, H.; Aerts, S.; Ranga, A.
10.1101/2020.09.22.308411 — bioengineering — Posted on 2020-09-22
1120 Why the COVID-19 pandemic is a traumatic stressor
Bridgland, V.; Moeck, E.; Green, D.; Swain, T.; Nayda, D.; Matson, L.; Hutchison, N.; Takarangi, M.
10.1101/2020.09.22.307637 — animal behavior and cognition — Posted on 2020-09-22
1122 Population Genomic Analyses Separate Historic Translocations from Contemporary Gene Flow in Arkansas White-tailed Deer (Odocoileus virginianus)
Chafin, T. K.; Zbinden, Z. D.; Douglas, M. R.; Martin, B. T.; Middaugh, C. R.; Gray, M. C.; Ballard, J. R.; Douglas, M. E.
10.1101/2020.09.22.308825 — evolutionary biology — Posted on 2020-09-22
1124 Mining the potential of VRS1-5 gene to raise barley grain yield
Yang, P.; Shen, L.; Liu, y.; wang, z.; sun, z.; Zhang, L.; Jiao, Y.; Wu, H.; Shen, K.; Cai, Y.; Guo, Z.
10.1101/2020.09.22.307876 — developmental biology — Posted on 2020-09-22
1125 Degenerating Drosophila Larval Epidermal Cells Drive Thorax Closure
Athilingam, T.; Parihar, S. S.; Bhattacharya, R.; Rizvi, M. S.; Kumar, A.; Sinha, P.
10.1101/2020.09.22.304451 — developmental biology — Posted on 2020-09-22
1126 Epigenetic clock and methylation studies in elephants
Prado, N. A.; Brown, J. L.; Zoller, J. Z.; Haghani, A.; Yao, M.; Bagryanova, L.; Campana, M.; Maldonado, J. E.; Raj, K.; Schmitt, D.; Robeck, T. R.; Horvath, S.
10.1101/2020.09.22.308882 — developmental biology — Posted on 2020-09-22
1127 Automated cell tracking using StarDist and TrackMate
Fazeli, E.; Roy, N. H.; Follain, G.; Laine, R. F.; von Chamier, L.; Hänninen, P.; Eriksson, J. E. H.; Tinevez, J.-Y.; Jacquemet, G.
10.1101/2020.09.22.306233 — cell biology — Posted on 2020-09-22
1132 A synergistic core for human brain evolution and cognition
Luppi, A. I.; Mediano, P. A. M.; Rosas, F. E.; Holland, N.; Fryer, T. D.; O'Brien, J. T.; Rowe, J. B.; Menon, D. K.; Bor, D.; Stamatakis, E. A.
10.1101/2020.09.22.308981 — neuroscience — Posted on 2020-09-22
1133 Chronic stress induces sex-specific functional and morphological alterations in cortico-accumbal and cortico-tegmental pathways.
Bittar, T. P.; Pelaez, M. C.; Hernandez Silva, J. C.; Quessy, F.; Lavigne, A.-A.; Morency, D.; Blanchette, L.-J.; Arsenault, E.; Cherasse, Y.; Seigneur, J.; Timofeev, I.; Sephton, C. F.; Proulx, C. D.; Labonte, B.
10.1101/2020.09.22.306860 — neuroscience — Posted on 2020-09-22
1135 Age-related differences in Autonomic/Central Coupling during a Daytime Nap
Chen, P.-C.; Simon, K. N.; Sattari, N.; Whitehurst, L. N.; Mednick, S. C.
10.1101/2020.09.22.297184 — neuroscience — Posted on 2020-09-22
1138 A Highly Conserved 310-Helix Within the Kinesin Motor Domain is Critical for Kinesin Function and Human Health.
Lam, A. J.; Rao, L.; Anazawa, Y.; Okada, K.; Chiba, K.; Niwa, S.; Gennerich, A.; Nowakowski, D. W.; McKenney, R. J.
10.1101/2020.09.22.308320 — biophysics — Posted on 2020-09-22
1142 Targeting Allostery in the Dynein Motor Domain with Small Molecule Inhibitors
Santarossa, C. C.; Mickolajczyk, K.; Steinman, J. B.; Urnavicius, L.; Chen, N.; Fukase, Y.; Hirata, Y.; Coudray, N.; Ekiert, D. C.; Bhabha, G.; Kapoor, T. M.
10.1101/2020.09.22.308700 — biochemistry — Posted on 2020-09-22
1145 Enrichment of novel Verrucomicrobia, Bacteroidetes and Krumholzibacteria in an oxygen-limited, methane- and iron-fed bioreactor inoculated with Bothnian Sea sediments
Dalcin Martins, P.; de Jong, A.; K. Lenstra, W.; A. G. M. van Helmond, N.; P. Slomp, C.; Jetten, M. S. M.; Welte, C. U.; Rasigraf, O.
10.1101/2020.09.22.307553 — microbiology — Posted on 2020-09-22
1146 The Clostridioides difficile species problem: global phylogenomic analysis uncovers three ancient, toxigenic, genomospecies
Knight, D. R.; Imwattana, K.; Kullin, B.; Guerrero-Araya, E.; Paredes-Sabja, D.; Didelot, X.; Dingle, K. E.; Eyre, D. W.; Rodriguez, C.; Riley, T. V.
10.1101/2020.09.21.307223 — microbiology — Posted on 2020-09-22
1149 The extracellular contractile injection system is enriched in environmental microbes and associates with numerous toxins
Geller, A. M.; Pollin, I.; Zlotkin, D.; Danov, A.; Nachmias, N.; Andreopoulos, W. B.; Shemesh, K.; Levy, A.
10.1101/2020.09.22.308684 — microbiology — Posted on 2020-09-22
1150 RNA adenosine deaminase ADAR2 modulates T helper 17 cell effector function
Ma, S.; Cho, B. S.; Li, Y.; Abbasi, N.; Yee, B. A.; Sun, G.; Luo, C.; Chang, J. T.; Zhou, B.; Fu, X.-d.; Yeo, G. W.; Huang, W. J. M.
10.1101/2020.09.22.308221 — immunology — Posted on 2020-09-22
1154 Single-molecule FRET dynamics of molecular motors in an ABEL Trap
Dienerowitz, M.; Howard, J.; Quinn, S. D.; Dienerowitz, F.; Leake, M. C.
10.1101/2020.09.21.306704 — biophysics — Posted on 2020-09-22
1158 Therapeutic inhibition of keratinocyte TRPV3 sensory channels by local anesthetic dyclonine
Yao, J.; Liu, Q.; Hu, J.; Wang, J.; Wei, X.; Ping, C.; Gao, Y.; Xie, C.; Yu, Y.; Li, D.
10.1101/2020.09.21.306316 — biochemistry — Posted on 2020-09-22
1159 Dynamic tracking and identification of tissue-specific secretory proteins in the circulation of live mice
Kim, K.-e.; Park, I.; Kim, J.; Kang, M.-G.; Choi, W. G.; Shin, H.; Kim, J.-S.; Rhee, H.-W.; Suh, J. M.
10.1101/2020.09.21.299198 — biochemistry — Posted on 2020-09-22
1160 Epigenetic clock and DNA methylation studies of roe deer in the wild
Lemaitre, J.-F.; Rey, B.; Gaillard, J.-M.; Regis, C.; Gilot, E.; Pellerin, M.; Haghani, A.; Zoller, J. A.; Li, C. Z.; Horvath, S.
10.1101/2020.09.21.306613 — evolutionary biology — Posted on 2020-09-22
1161 The evolutionary dynamics of genetic incompatibilities introduced by duplicated genes in Arabidopsis thaliana
Jiao, W.-B.; Patel, V.; Klasen, J.; Liu, F.; Pecinkova, P.; Ferrand, M.; Gy, I.; Camilleri, C.; Effgen, S.; Koornneef, M.; Pecinka, A.; Loudet, O.; Schneeberger, K.
10.1101/2020.09.21.306035 — evolutionary biology — Posted on 2020-09-22
1163 A cell-autonomous PD-1/PD-L1 circuit promotes tumorigenicity of thyroid cancer cells by activating a SHP2/Ras/MAPK signalling cascade
Liotti, F.; Kumar, N.; Prevete, N.; Marotta, M.; Sorriento, D.; Ierano, C.; Ronchi, A.; Zito Marino, F.; Moretti, S.; Colella, R.; Puxeddu, E.; Paladino, S.; Kano, Y.; Ohh, M.; Scala, S.; Melillo, R. M.
10.1101/2020.09.22.307942 — cancer biology — Posted on 2020-09-22
1164 The Structures of SctK and SctD from Pseudomonas aeruginosa Reveal the Interface of the Type III Secretion System Basal Body and Sorting Platform
Muthuramalingam, M.; Whittier, S.; Lovell, S.; Battaile, K. P.; Tachiyama, S.; Johnson, D. K.; Picking, W. L.; Picking, W. D.
10.1101/2020.09.22.308627 — biophysics — Posted on 2020-09-22
1168 Copy-scAT: An R package for detection of large-scale and focal copy number alterations in single-cell chromatin accessibility datasets
Nikolic, A.; Signal, D.; Ellestad, K.; Johnston, M.; Gillmor, A.; Morrissy, S.; Chan, J. A.; Neri, P.; Bahlis, N.; Gallo, M.
10.1101/2020.09.21.305516 — bioinformatics — Posted on 2020-09-22
1169 SingleChannelNet: A model for Automatic Sleep Stage Classification with Raw Single-Channel EEG
Zhou, D.; Hu, G.; Zhang, J.; Yan, R.; Li, F.; Xu, Q.; Kettunen, L.; Chang, Z.; Cong, F.
10.1101/2020.09.21.306597 — bioengineering — Posted on 2020-09-22
1170 Characterization of Wnt Signaling Genes in Diaphorina citri
Vosburg, C.; Reynolds, M.; Noel, R.; Shippy, T.; Hosmani, P. S.; Flores-Gonzalez, M.; Mueller, L. A.; Hunter, W. B.; Brown, S. J.; D'elia, T.; Saha, S.
10.1101/2020.09.21.306100 — genomics — Posted on 2020-09-22
1171 EPISPOT: an epigenome-driven approach for detecting and interpreting hotspots in molecular QTL studies
Ruffieux, H.; Fairfax, B.; Nassiri, I.; Vigorito, E.; Wallace, C.; Richardson, S.; Bottolo, L.
10.1101/2020.09.21.305789 — genetics — Posted on 2020-09-22
1172 Cryptic diversity masks ecologically distinct coral species on tropical reefs
Bongaerts, P.; Cooke, I. R.; Ying, H.; Wels, D.; den Haan, S.; Hernandez-Agreda, A.; Brunner, C. A.; Dove, S.; Englebert, N.; Eyal, G.; Foret, S.; Grinblat, M.; Hay, K. B.; Harii, S.; Hayward, D. C.; Lin, Y.; Mihaljevic, M.; Moya, A.; Muir, P.; Sinniger, F.; Smallhorn-West, P.; Torda, G.; Ragan, M. A.; van Oppen, M. J.; Hoegh-Guldberg, O.
10.1101/2020.09.04.260208 — evolutionary biology — Posted on 2020-09-22
1173 Neonicotinoids stimulate H2-limited methane emission in Periplaneta americana through the regulation of gut bacterium community
Bao, H.; Gao, H.; Zhang, J.; Lu, H.; Yu, N.; Shao, X.; Zhang, Y.; Jin, W.; Li, S.; Xu, X.; Tian, J.; Xu, Z.; Li, Z.; Liu, Z.
10.1101/2020.09.21.307298 — ecology — Posted on 2020-09-22
1175 Mis-splicing of Mdm2 leads to increased P53-activity and craniofacial defects in a MFDM Eftud2 mutant mouse model
Beauchamp, M.-C.; Djedid, A.; Bareke, E.; Merkuri, F.; Aber, R.; Tam, A. S.; Lines, M. A.; Boycott, K. M.; Stirling, P. C.; Fish, J. L.; Majewski, J. L.; Jerome-Majewska, L. A.
10.1101/2020.09.22.308205 — developmental biology — Posted on 2020-09-22
1176 Rapid changes in chromatin structure during dedifferentiation of primary hepatocytes in vitro
Seirup, M.; Sengupta, S.; Swanson, S.; McIntosh, B. E.; Collins, M.; Chu, L.-F.; Cheng, Z.; Gorkin, D.; Duffin, B.; Bolin, J. M.; Argus, C.; Stewart, R.; Thomson, J. A.
10.1101/2020.09.21.307363 — cell biology — Posted on 2020-09-22
1177 Sox2-RNA mechanisms of chromosome topological control in developing forebrain
Cajigas, I.; Luo, H.; Chakraborty, A.; Lynam, M.; Swyter, K.; Bastidas, M.; Collens, L.; Ay, F.; Kohtz, J. D.
10.1101/2020.09.22.307215 — molecular biology — Posted on 2020-09-22
1181 Temporal dynamics of functional networks in long-term infant scalp EEG
Smith, R. J.; Alipourjeddi, E.; Garner, C.; Maser, A. L.; Shrey, D. W.; Lopour, B. A.
10.1101/2020.09.21.307082 — neuroscience — Posted on 2020-09-22
1182 Chronic in vivo STED nanoscopy uncovers multiple drivers of shape volatility in stable cortical spines
Steffens, H.; Mott, A. C.; Li, S.; Wegner, W.; Svehla, P.; Kan, V. W. Y.; Wolf, F.; Liebscher, S.; Willig, K. I.
10.1101/2020.09.21.306902 — neuroscience — Posted on 2020-09-22
1184 Probing Causality of the Brainstem-Hypothalamic Murine Models of Sleep-Wake Regulation
Bahari, F.; Billard, M. W.; Kimbugwe, J.; Curay, C.; Watson, G. D. R.; Alloway, K. D.; Gluckman, B. J.
10.1101/2020.09.21.306456 — neuroscience — Posted on 2020-09-22
1186 Insufficient Eye Tracking Data Leads to Errors in Evaluating Typical and Atypical Fixation Preferences
Reimann, G. E.; Walsh, C.; Csumitta, K.; McClure, P.; Pereira, F.; Martin, A.; Ramot, M.
10.1101/2020.09.21.306621 — neuroscience — Posted on 2020-09-22
1192 Multiplex-inhibitor bead mass spectrometry reveals differential kinome signatures in newly diagnosed and recurrent glioblastoma
Jermakowicz, A. D.; Kurimchak, A. M.; Sarkaria, J.; Komotar, R.; Ivan, M. E.; Schürer, S.; Duncan, J. S.; Ayad, N.
10.1101/2020.09.21.306910 — cancer biology — Posted on 2020-09-22
1193 Is structure based drug design ready for selectivity optimization?
Albanese, S. K.; Chodera, J. D.; Volkamer, A.; Keng, S.; Abel, R.; Wang, L.
10.1101/2020.07.02.185132 — biophysics — Posted on 2020-09-22
1196 Analysis of ISCB honorees and keynotes reveals disparities
Le, T. T.; Himmelstein, D. S.; Hippen Anderson, A. A.; Gazzara, M. R.; Greene, C. S.
10.1101/2020.04.14.927251 — bioinformatics — Posted on 2020-09-22
1199 Multivariate GWAS elucidates the genetic architecture of alcohol consumption and misuse, corrects biases, and reveals novel associations with disease
Mallard, T. T.; Savage, J. E.; Johnson, E. C.; Huang, Y.; Edwards, A. C.; Hottenga, J. J.; Grotzinger, A. D.; Gustavson, D. E.; Jennings, M. V.; Anokhin, A.; Dick, D. M.; Edenberg, H. J.; Kramer, J. R.; Lai, D.; Meyers, J. L.; Pandey, A. K.; Harden, K. P.; Nivard, M. G.; de Geus, E. J.; Boomsma, D. I.; Agrawal, A.; Davis, L. K.; Clarke, T.-K.; Palmer, A. A.; Sanchez-Roige, S.
10.1101/2020.09.21.304196 — genetics — Posted on 2020-09-22
1202 Large-scale characterization of sex pheromone communication systems in Drosophila
Khallaf, M. A.; Cui, R.; Weissflog, J.; Svatos, A.; Dweck, H. K. M.; Valenzano, D. R.; Hansson, B. S.; Knaden, M.
10.1101/2020.09.21.305854 — evolutionary biology — Posted on 2020-09-22
1204 Epigenetic clock and methylation studies in the rhesus macaque
Horvath, S.; Zoller, J. Z.; Haghani, A.; Jasinska, A. J.; Raj, K.; Breeze, C.; Ernst, J.; Mattison, J. A.
10.1101/2020.09.21.307108 — developmental biology — Posted on 2020-09-22
1205 Steric-Free Bioorthogonal Labeling of Acetylation Substrates Based on a Fluorine-Thiol Displacement Reaction (FTDR)
Lyu, Z.; Zhao, Y.; Buuh, Z. Y.; Gorman, N.; Goldman, A. R.; Islam, M. S.; Tang, H.-Y.; Wang, R. E.
10.1101/2020.09.09.290221 — cell biology — Posted on 2020-09-22
1206 Remarkable recent changes in genetic diversity of the avirulence gene AvrStb6 in global populations of the wheat pathogen Zymoseptoria tritici
Stephens, C.; Olmez, F.; Blyth, H.; McDonald, M.; Bansal, A.; Turgay, E. B.; Hahn, F.; Saintenac, C.; Nekrasov, V.; Solomon, P.; Milgate, A.; Fraaije, B.; Rudd, J. J.; Kanyuka, K.
10.1101/2020.09.18.303370 — microbiology — Posted on 2020-09-22
1209 Mass cytometry and artificial intelligence define CD169 as a specific marker of SARS-CoV2-induced acute respiratory distress syndrome
Roussel, M.; Ferrant, J.; Reizine, F.; Le Gallou, S.; Dulong, J.; Carl, S.; Lesouhaitier, M.; Gregoire, M.; Bescher, N.; Verdy, C.; Latour, M.; Bezier, I.; Cornic, M.; Leonard, S.; Feuillard, J.; Tiwari, V.; Tadie, J. M.; Cogne, M.; Tarte, K.
10.1101/2020.09.22.307975 — immunology — Posted on 2020-09-22
1210 NeutrobodyPlex - Nanobodies to monitor a SARS-CoV-2 neutralizing immune response
Wagner, T.; Kaiser, P. D.; Gramlich, M.; Becker, M.; Traenkle, B.; Junker, D.; Haering, J.; Nueske, S.; Scholz, A.; Zeck, A.; Schenke-Layland, K.; Nelde, A.; Strengert, M.; Krause, G.; Walz, J. S.; Ruetalo, N.; Schindler, M.; Schneiderhan-Marra, N.; Rothbauer, U.
10.1101/2020.09.22.308338 — immunology — Posted on 2020-09-22
1211 Bat and pangolin coronavirus spike glycoprotein structures provide insights into SARS-CoV-2 evolution
Wang, X.; Zhang, S.; Qiao, S.; Yu, J.; Zeng, J.; Shan, S.; Lan, J.; Tian, L.; Zhang, L.
10.1101/2020.09.21.307439 — biophysics — Posted on 2020-09-22
1212 Protonation states in SARS-CoV-2 main protease mapped by neutron crystallography
Kneller, D. W.; Phillips, G.; Weiss, K. L.; Pant, S.; Zhang, Q.; O'Neill, H.; Coates, L.; Kovalevsky, A.
10.1101/2020.09.22.308668 — biochemistry — Posted on 2020-09-22
1213 Coordinated interactions between endothelial cells and macrophages in the islet microenvironment promote beta cell regeneration
Saunders, D. C.; Aamodt, K. I.; Richardson, T. M.; Hopkirk, A.; Aramandla, R.; Poffenberger, G.; Jenkins, R.; Flaherty, D. K.; Prasad, N.; Levy, S.; Powers, A.; Brissova, M.
10.1101/2020.08.28.265728 — cell biology — Posted on 2020-09-22
1214 High prevalence of SARS-CoV-2 antibodies in pets from COVID-19+ households
Fritz, M.; Rosolen, B.; Krafft, E.; Becquart, P.; Elguero, E.; Vratskikh, O.; Denolly, S.; Boson, B.; Vanhomwegen, J.; Ar Gouilh, M.; Kodjo, A.; Chirouze, C.; Rosolen, S.; Legros, V.; Leroy, E. M.
10.1101/2020.09.22.307751 — microbiology — Posted on 2020-09-22
1215 Humoral response to SARS-CoV-2 by healthy and sick dogs during COVID-19 pandemic in Spain.
Perise-Barrios, A. J.; Tomeo-Martin, B. D.; Gomez-Ochoa, P.; Delgado-Bonet, P.; Plaza, P.; Palau-Concejo, P.; Gonzalez, J.; Ortiz-Diez, G.; Melendez-Lazo, A.; Gentil, M.; Garcia-Castro, J.; Barbero-Fernandez, A.
10.1101/2020.09.22.308023 — microbiology — Posted on 2020-09-22
1217 NREM consolidation and increased spindle counts improve age-related memory impairments and hippocampal representations
Yuan, R. K.; Lopez, M. R.; Ramos-Alavarez, M.-M.; Normandin, M. E.; Thomas, A. S.; Uygun, D. S.; Cerda, V. R.; Grenier, A. E.; Wood, M. T.; Gagliardi, C. M.; Muzzio, I. A.
10.1101/2020.01.20.912915 — neuroscience — Posted on 2020-09-22
1219 Chronic IL-1 exposure drives LNCaP cells to evolve androgen and AR independence
Dahl, H.; Kanchwala, M.; Thomas-Jardin, S.; Sandhu, A.; Kanumuri, P.; Nawas, A. F.; Xing, C.; Lin, C.; Frigo, D. E.; Delk, N.
10.1101/2020.04.21.054452 — cancer biology — Posted on 2020-09-22
1220 AI-guided discovery of the invariant host response to viral pandemics
Sahoo, D.; Katkar, G. D.; Khandelwal, S.; Behroozikhah, M.; Claire, A.; Castillo, V.; Tindle, C.; Fuller, M.; Taheri, S.; Rogers, T. F.; Beutler, N.; Ramirez, S.; Rawlings, S. A.; Pretorius, V.; Smith, D.; Burton, D. R.; Alexander, L. C.; Duran, J. M.; Crotty, S.; Dan, J. M.; Das, S.; Ghosh, P.
10.1101/2020.09.21.305698 — bioinformatics — Posted on 2020-09-22
1221 Tissue Engineered Axon-Based Living Scaffolds Promote Survival of Spinal Cord Motor Neurons Following Peripheral Nerve Repair
Maggiore, J. C.; Burrell, J. C.; Browne, K. D.; Katiyar, K. C.; Laimo, F. A.; Ali, Z.; Kaplan, H. M.; Rosen, J. M.; Cullen, D. K.
10.1101/847988 — bioengineering — Posted on 2020-09-22
1222 Single-cell multimodal omics and directly reprogrammed neurons to probe reduced penetrance in Frontotemporal Dementia
Natarajan, K.; Eisfeldt, J.; Hammond, M.; Patra, K.; Laffita-Mesa, J. M.; Talavera, Y. a.; Birtele, M.; Oijerstedt, L.; Fisahn, A.; Parmar, M.; graff, c.
10.1101/2020.09.22.270199 — neuroscience — Posted on 2020-09-22
1229 ELR is a true pattern recognition receptor that associates with elicitins from diverse Phytophthora species
Domazakis, E.; Wouters, D.; Lochman, J.; Visser, R.; Joosten, M. H. A. J.; Vleeshouwers, V. G. A. A.
10.1101/2020.09.21.305813 — plant biology — Posted on 2020-09-22
1230 Europe as a bridgehead in the worldwide invasion history of grapevine downy mildew, Plasmopara viticola
Fontaine, M. C.; Labbe, F.; Dussert, Y.; Deliere, L.; Richart-Cervera, S.; Giraud, T.; Delmotte, F.
10.1101/2020.09.22.307678 — evolutionary biology — Posted on 2020-09-22
1232 Impaired M-current in KCNQ2 Encephalopathy Evokes Dyshomeostatic Modulation of Excitability
Simkin, D.; Searl, T. J.; Piyevsky, B. N.; Forrest, M.; Williams, L. A.; Joshi, V.; Zhang, H.; Ryan, S. J.; Schwake, M.; Robertson, G. L.; Penzes, P.; Laux, L. C.; McManus, O. B.; Dempsey, G. T.; Millichap, J. J.; George, A. L.; Kiskinis, E.
10.1101/538371 — neuroscience — Posted on 2020-09-22
1233 Transcriptome analysis of potato leaves in response to infection with the necrotrophic pathogen Alternaria solani
Tian, M.; Wang, J.; Zhu, J.; Yang, Z.; Li, Z.; Wang, C.; Zhang, D.; Yang, Y.; Pan, Y.; Zhao, D.
10.1101/2020.09.21.307314 — plant biology — Posted on 2020-09-22
1234 Optimized cultivar deployment improves the efficiency and stability of sunflower crop production at national scale
Casadebaig, P.; Gauffreteau, A.; Landre, A.; Langlade, N.; Mestries, E.; Sarron, J.; Trepos, R.; Vincourt, P.; Debaeke, P.
10.1101/2020.09.21.306076 — plant biology — Posted on 2020-09-22
1235 A bacterial effector uncovers a metabolic pathway involved in resistance to bacterial wilt disease
Wang, Y.; Morcillo, R. J.; Yu, G.; Zhao, A.; Xue, H.; Rufian, J. S.; Sang, Y.; Macho, A.
10.1101/2020.09.22.307595 — plant biology — Posted on 2020-09-22
1237 Proneural genes define ground state rules to regulate neurogenic patterning and cortical folding
Han, S.; Wilkinson, G. A.; Okawa, S.; Adnani, L.; Dixit, R.; Faisal, I.; Brooks, M.; Cortay, V.; Chinchalongporn, V.; Zinyk, D.; Li, S.; Gao, J.; Malik, F.; Touahri, Y.; Angarica, V. E.; Oproescu, A.-M.; Raharjo, E.; Ilnytskyy, Y.; Kim, J.-W.; Wu, W.; Rahmani, W.; Kovalchuk, I.; Chan, J. A.-w.; Kurrasch, D.; Castro, D. S.; Dehay, C.; Swaroop, A.; Biernaskie, J.; del Sol, A.; Schuurmans, C.
10.1101/2020.09.22.307058 — developmental biology — Posted on 2020-09-22
1238 MANF regulates unfolded protein response and neuronal survival through its ER-located receptor IRE1α
Kovaleva, V.; Yu, L.-Y.; Ivanova, L.; Nam, J.; Eesmaa, A.; Kumpula, E.-P.; Huiskonen, J.; Lindholm, P.; Voutilainen, M. H.; Karelson, M.; Saarma, M.
10.1101/2020.09.22.307744 — cell biology — Posted on 2020-09-22
1242 Piperacillin/tazobactam resistant, cephalosporin susceptible Escherichia coli bloodstream infections driven by multiple resistance mechanisms across diverse sequence types
Edwards, T.; Heinz, E.; van Aartsen, J.; Howard, A.; Roberts, P.; Corless, C.; Fraser, A. J.; Williams, C. T.; Bulgasim, I.; Cuevas, L. E.; Parry, C. M.; Roberts, A. P.; Adams, E. R.; Mason, J.; Hubbard, A.
10.1101/2020.09.18.302992 — microbiology — Posted on 2020-09-22
1243 Synchronous nonmonotonic changes in functional connectivity and white matter integrity in a rat model of sporadic Alzheimer's disease
Tristao Pereira, C.; Diao, Y.; Yin, T.; Da Silva, A. R.; Lanz, B.; Pierzchala, K.; Poitry-Yamate, C.; Jelescu, I. O.
10.1101/2020.01.30.926444 — neuroscience — Posted on 2020-09-22
1244 CD39+PD-1+CD8+ T cells mediate metastatic dormancy in breast cancer
Tallon de Lara, P.; Castanon, H.; Vermeer, M.; Nunez, N.; Silina, K.; Sobottka, B.; Urdinez, J.; Cecconi, V.; Movahedian Attar, F.; Hiltbrunner, S.; Glarner, I.; Moch, H.; Tugues, S.; Becher, B.; van den Broek, M.
10.1101/2020.06.02.126037 — cancer biology — Posted on 2020-09-22
1245 Bulk-surface coupling reconciles Min-protein pattern formation in vitro and in vivo
Brauns, F.; Pawlik, G.; Halatek, J.; Kerssemakers, J. W. J.; Frey, E.; Dekker, C.
10.1101/2020.03.01.971952 — biophysics — Posted on 2020-09-22
1247 Mapping the genetic and environmental aetiology of autistic traits in Sweden and the UK
Reed, Z. E.; Larsson, H.; Haworth, C. M. A.; Rai, D.; Lundstrom, S.; Ronald, A.; Reichenberg, A.; Lichtenstein, P.; Davis, O. S. P.
10.1101/2020.04.14.031518 — genetics — Posted on 2020-09-22
1256 Spatial enrichment of phosphoinositide metabolism is a molecular switch to promote metastasis.
Nacke, M.; Sandilands, E.; Nikolatou, K.; Roman-Fernandez, A.; Mason, S.; Patel, R.; Lilla, S.; Yelland, T.; Galbraith, L.; McGarry, L.; Morton, J. P.; Shanks, E.; Leung, H. Y.; Zanivan, S.; Ismail, S.; Markert, E.; Blyth, K.; Bryant, D.
10.1101/851410 — cancer biology — Posted on 2020-09-22
1257 CellexalVR: A virtual reality platform to visualise and analyse single-cell data
Legetth, O.; Rodhe, J.; Lang, S.; Dhapola, P.; Palsson, J.; Wallergard, M.; Soneji, S.
10.1101/329102 — bioinformatics — Posted on 2020-09-22
1259 An automatic pipeline for the design of irreversible derivatives identifies a potent SARS-CoV-2 Mpro inhibitor.
Zaidman, D.; Gehrtz, P.; Filep, M.; Fearon, D.; Prilusky, J.; Duberstein, S.; Cohen, G.; Owen, D.; Resnick, E.; Strain-Damerell, C.; Lukacik, P.; Covid-Moonshot Consortium, ; Barr, H.; A. Walsh, M.; von Delft, F.; London, N.
10.1101/2020.09.21.299776 — biochemistry — Posted on 2020-09-22
1265 Antioxidant enriched fraction from Pueraria tuberosa alleviates ovariectomized-induced osteoporosis in rats, and inhibits growth of breast and ovarian cancer cell lines in vitro
Satpathy, S.; Patra, A.; Hussain, M. D.; Kazi, M.; Aldughaim, M. S.; Ahirwar, B.; Swaha Satpathy, Arjun Patra, Muhammad Delwar Hussain, Mohsin Kazi, Mohammed S Aldughaim, Bharti Ahir,
10.1101/2020.09.21.305953 — pharmacology and toxicology — Posted on 2020-09-21
1266 Modelling locust foraging: How and why food affects hopper band formation
Georgiou, F. H.; Buhl, J.; Green, J. E. F.; Lamichhane, B.; Thamwattana, N.
10.1101/2020.09.21.305896 — biochemistry — Posted on 2020-09-21
1271 Prevailing role of mucosal immunoglobulions and B cells in teleost skin immune responses to bacterial infection
Zhang, X.; Yu, Y.; Xu, H.; Huang, Z.; Liu, X.; Cao, J.; Meng, K.; Wu, Z.; Han, G.; Zhan, M.; Ding, L.; Kong, W.; Li, N.; Takizawa, F.; Sunyer, O.; xu, z.
10.1101/2020.09.21.305920 — immunology — Posted on 2020-09-21
1272 Mecamylamine inhibits seizure-like activity in CA1-CA3 hippocampus through antagonism to nicotinic receptors
Zapukhliak, O.; Netsyk, O.; Romanov, A.; Maximyuk, O.; Oz, M.; Holmes, G. L.; Krishtal, O.; Isaev, D.
10.1101/2020.09.21.306019 — neuroscience — Posted on 2020-09-21
1276 Stabilization of p53 by microRNAs in HPV-positive cervical cancer cells
Howley, P. M.; Martinez-Noël, G.; Szajner, P.; Smith, J. A.; Boyland, K.; Kramer, R. E.
10.1101/2020.09.21.305946 — cancer biology — Posted on 2020-09-21
1278 Nitrate and nitrite exposure increases anxiety-like behavior and alters brain metabolomic profile in zebrafish
Garcia - Jaramillo, M.; Beaver, L. M.; Truong, L.; Axton, E. R.; Keller, R. M.; Prater, M. C.; Magnusson, K. R.; Tanguay, R. L.; Stevens, J. F.; Hord, N. G.
10.1101/2020.09.21.305979 — animal behavior and cognition — Posted on 2020-09-21
1279 The complex evolution of the HSP70 gene family
Yu, E.; Yoshinaga, T.; Jalufka, F. L.; Ehsan, H.; Mark Welch, D. B.; Kaneko, G.
10.1101/2020.09.21.307264 — evolutionary biology — Posted on 2020-09-21
1281 Integrative systems approach reveals dynamics of microbiome-metal-ion axis in mesocosms representing tropical urban freshwater canal ecosystem
Saxena, G.; Hill, E. D.; Marzinelli, E. M.; Umashankar, S.; Wei, T. J.; Yissue, W. W.; Steinberg, P. D.; Rajal, V. B.; Kjelleberg, S.; Williams, R.; Wuertz, S.; Swarup, S.
10.1101/2020.09.21.306803 — ecology — Posted on 2020-09-21
1284 Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection
Dobrindt, K.; Hoagland, D. A.; Seah, C.; Kassim, B.; O'Shea, C. P.; Iskhakova, M.; Fernando, M.; Deans, P. M.; Powell, S. K.; Javidfar, B.; Murphy, A.; Peter, C.; Moeller, R.; Fernandez Garcia, M.; Kimura, M.; Iwasawa, K.; Crary, J.; Kotton, D.; Takebe, T.; Huckins, L.; tenOever, B.; Akbarian, S.; Brennand, K. J.
10.1101/2020.09.20.300574 — cell biology — Posted on 2020-09-21
1286 Hypothalamic estrogen receptor alpha mediates key side effects of tamoxifen therapy in mice
Zhang, Z.; Park, J. W.; Ahn, I.; Diamante, G.; Sivakumar, N.; Arneson, D.; Yang, X.; van Veen, J. E.; Correa, S. M.
10.1101/2020.09.21.307124 — neuroscience — Posted on 2020-09-21
1287 An Interpreted Atlas of Biosynthetic Gene Clusters from 1000 Fungal Genomes
Robey, M. T.; Caesar, L. K.; Drott, M. T.; Keller, N. P.; Kelleher, N. L.
10.1101/2020.09.21.307157 — biochemistry — Posted on 2020-09-21
1292 The gut microbiome stability of a butterflyfish is disrupted on severely degraded Caribbean coral reefs
Clever, F.; Sourisse, J. M.; Preziosi, R. F.; Eisen, J. A.; Guerra, E. C.; Scott, J. J.; Wilkins, L. G. E.; Altieri, A. H.; McMillan, W. O.; Leray, M.
10.1101/2020.09.21.306712 — ecology — Posted on 2020-09-21
1293 Robust differentiation of human enteroendocrine cells from intestinal stem cells
Zeve, D.; Stas, E.; Yin, X.; Dubois, S.; Shah, M. S.; Syverson, E. P.; Hafner, S.; Karp, J. M.; Carlone, D. L.; Breault, D. T.
10.1101/2020.09.21.303990 — developmental biology — Posted on 2020-09-21
1296 Renal proximal tubule cell state and metabolism are coupled by nuclear receptors
Park, J.; dhillon, p.; Hurtado, C.; Li, L.; Huang, S.; Zhao, J.; Kang, H. M.; Shrestra, R.; Blazer, M. S.; Chatterjee, S.; Prado, P.; Han, S.; Liu, H.; Sheng, X.; Batmanov, K.; Rojas, J. P.; Prosper, F.; Li, M.; Pei, L.; Kim, J.; Monserrat, N.; Susztak, K.
10.1101/2020.09.21.307231 — cell biology — Posted on 2020-09-21
1297 Routes to Roots: Direct Evidence of Water Transport by Arbuscular Mycorrhizal Fungi to Host Plants
Kakouridis, A.; Hagen, J. A.; Kan, M. P.; Mambelli, S.; Feldman, L. J.; Herman, D. J.; Pett-Ridge, J.; Firestone, M. K.
10.1101/2020.09.21.305409 — microbiology — Posted on 2020-09-21
1298 Tricarboxylic acid cycle and proton gradient in Pandoravirus massiliensis: Is it still a virus?
Aherfi, S.; BRAHIM BELHAOUARI, D.; Pinault, L.; Baudoin, J.-P.; Decloquement, P.; Abrahao, J.; Colson, P.; LEVASSEUR, A.; Lamb, D. C.; Chabriere, E.; Raoult, D.; LA SCOLA, B.
10.1101/2020.09.21.306415 — microbiology — Posted on 2020-09-21
1299 Two-target quantitative PCR to predict library composition for shallow shotgun sequencing
Cho, M. Y.; Oliva, M.; Spreafico, A.; Chen, B.; Wei, X.; Choi, Y.; Kaul, R.; Siu, L. L.; Coburn, B.; Schneeberger, P. H. H.
10.1101/2020.09.21.304006 — microbiology — Posted on 2020-09-21
1301 A common binding motif in the ET domain of BRD3 forms polymorphic structural interfaces with host and viral proteins
Aiyer, S.; Swapna, G. V. T.; Liu, G.; Ma, L.-C.; Hao, J.; Chalmers, G.; Jacobs, B.; Montelione, G. T.; Roth, M. J.
10.1101/2020.09.21.306696 — microbiology — Posted on 2020-09-21
1302 Evidence for current circulation of an ancient West Nile virus strain (NY99) in Brazil
Siconelli, M. J. L.; Jorge, D. M. d. M.; Castro-Jorge, L. A. d.; Fonseca-Junior, A. A.; Nascimento, M. L.; Floriano, V. G.; Souza, F. R. d.; Queiroz-Junior, E. M. d.; Camargos, M. F.; Costa, E. D. L.; Carvalho, A. A. B.; Fonseca, B. A. L. d.
10.1101/2020.09.21.307199 — microbiology — Posted on 2020-09-21
1304 CD8+ T cell priming in oral mucosa-draining lymph nodes supports systemic immunity
Barreto de Albuquerque, J.; von Werdt, D.; Francisco, D.; van Geest, G.; Altenburger, L. M.; Abe, J.; Ficht, X.; Iannacone, M.; Bruggmann, R.; Mueller, C.; Stein, J. V.
10.1101/2020.09.21.306449 — immunology — Posted on 2020-09-21
1307 Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts
Quinn, J. J.; Jones, M. G.; Okimoto, R. A.; Nanjo, S.; Chan, M. M.; Yosef, N.; Bivona, T. G.; Weissman, J. S.
10.1101/2020.04.16.045245 — cancer biology — Posted on 2020-09-21
1308 The genetic status of IDH1/2 and EGFR dictates the vascular landscape and the progression of gliomas
Segura-Collar, B.; Garranzo-Asensio, M.; Herranz, B.; Hernandez-SanMiguel, E.; Casas, B. S.; Matheu, A.; Perez-Nunez, A.; Sepulveda-Sanchez, J. M.; Hernandez-Lain, A.; Palma, V.; Gargini, R.; Sanchez-Gomez, P.
10.1101/2020.09.21.306134 — cancer biology — Posted on 2020-09-21
1309 DNA-Origami-Based Fluorescence Brightness Standards for Convenient and Fast Protein Counting in Live Cells
Williams, N. D.; Landajuela, A.; Kasula, R. K.; Zhou, W.; Powell, J. T.; Xi, Z.; Isaacs, F. J.; Berro, J.; Toomre, D.; Karatekin, E.; Lin, C.
10.1101/2020.09.20.305359 — biophysics — Posted on 2020-09-21
1311 Biochemical reconstitutions reveal principles of human γ-TuRC assembly and function
Wieczorek, M.; Ti, S.-C.; Urnavicius, L.; Molloy, K. R.; Aher, A.; Chait, B. T.; Kapoor, T. M.
10.1101/2020.09.21.306845 — biochemistry — Posted on 2020-09-21
1312 Regulation of protein abundance in genetically diverse mouse populations
Keele, G. R.; Zhang, T.; Pham, D. T.; Vincent, M.; Bell, T. A.; Hock, P.; Shaw, G. D.; Munger, S. C.; de Villena, F. P.-M.; Ferris, M. T.; Gygi, S. P.; Churchill, G. A.
10.1101/2020.09.18.296657 — genomics — Posted on 2020-09-21
1315 A comprehensive and high-quality collection of E. coli genomes and their genes
Horesh, G.; Blackwell, G.; Tonkin-Hill, G.; Corander, J.; Heinz, E.; Thomson, N.
10.1101/2020.09.21.293175 — genomics — Posted on 2020-09-21
1316 Open Targets Genetics: An open approach to systematically prioritize causal variants and genes at all published human GWAS trait-associated loci
Mountjoy, E.; Schmidt, E. M.; Carmona, M.; Peat, G.; Miranda, A.; Fumis, L.; Hayhurst, J.; Buniello, A.; Schwartzentruber, J.; Karim, M. A.; Wright, D.; Hercules, A.; Papa, E.; Fauman, E.; Barrett, J. C.; Todd, J. A.; Ochoa, D.; Dunham, I.; Ghoussaini, M.
10.1101/2020.09.16.299271 — genetics — Posted on 2020-09-21
1317 Natural selection and the advantage of recombination
Gerrish, P. J.; Galeota-Sprung, B.; Cordero, F.; Sniegowski, P. D.; Colato, A.; Hengartner, N. W.; Vejalla, V.; Chevalier, J.; Ycart, B.
10.1101/2020.08.28.271486 — evolutionary biology — Posted on 2020-09-21
1321 RhoGAP19D inhibits Cdc42 laterally to control epithelial cell shape and prevent invasion
Fic, W.; Bastock, R.; Raimondi, F.; Los, E.; Inoue, Y.; Gallop, J.; Russell, R. B.; St Johnston, D.
10.1101/2020.09.17.300145 — cell biology — Posted on 2020-09-21
1322 Fibrinogen anchors for micropatterning of active proteins and subcellular receptor relocalisation
Watson, J. L.; Aich, S.; Oller-Salvia, B.; Drabek, A. A.; Blacklow, S.; chin, J.; Derivery, E.
10.1101/2020.09.04.256875 — cell biology — Posted on 2020-09-21
1325 A synthetic kinematic index of trunk displacement conveying the overall motor condition in Parkinson's disease
Troisi Lopez, E.; Minino, R.; Sorrentino, P.; Rucco, R.; Carotenuto, A.; Agosti, V.; Tafuri, D.; Manzo, V.; Liparoti, M.; Sorrentino, G.
10.1101/2020.07.13.199224 — neuroscience — Posted on 2020-09-21
1327 Vascular calcification has a role in acute non-renal phosphate clearance
Turner, M. E.; Lansing, A. P.; Jeronimo, P. S.; Lee, L. H.; Svajger, B. A.; Zelt, J. G.; Forster, C. M.; Petkovich, M. P.; Holden, R. M.; Adams, M. A.
10.1101/2020.07.29.225532 — pathology — Posted on 2020-09-21
1328 Base-pair resolution analysis of the effect of supercoiling on DNA flexibility and major groove recognition by triplex-forming oligonucleotides
Pyne, A. L. B.; Noy, A.; Main, K.; Velasco-Berrelleza, V.; Piperakis, M. M.; Mitchenhall, L. A.; Cugliandolo, F. M.; Beton, J. G.; Stevenson, C. E. M.; Hoogenboom, B. W.; Bates, A. D.; Maxwell, A.; Harris, S. A.
10.1101/863423 — biophysics — Posted on 2020-09-21
1330 Exhaustive identification of conserved upstream open reading frames with potential translational regulatory functions from animal genomes
Takahashi, H.; Miyaki, S.; Onouchi, H.; Motomura, T.; Idesako, N.; Takahashi, A.; Murase, M.; Fukuyoshi, S.; Endo, T.; Satou, K.; Naito, S.; Itoh, M.
10.1101/672840 — bioinformatics — Posted on 2020-09-21
1333 A telomere to telomere assembly of Oscheius tipulae and the evolution of rhabditid nematode chromosomes
Gonzalez de la Rosa, P. M.; Thomson, M.; Trivedi, U.; Tracey, A.; Tandonnet, S.; Blaxter, M.
10.1101/2020.09.04.283127 — genomics — Posted on 2020-09-21
1338 ANTIMETABOLIC COOPERATIVITY WITH THE CLINICALLY APPROVED KIDROLASE AND TYROSINE KINASE INHIBITORS TO ERADICATE CML STEM CELLS
Trinh, A.; Khamari, R.; Fovez, Q.; Mahon, F.-X.; Turcq, B.; Bouscary, D.; Maboudou, P.; Joncquel, M.; Coiteux, V.; Germain, N.; Laine, W.; Dekiouk, S.; Ghesquiere, B.; Idziorek, T.; Quesnel, B.; Kluza, J.; Marchetti, P.
10.1101/2020.09.21.305714 — cancer biology — Posted on 2020-09-21
1339 Functional and structural characterization of interactions between opposite subunits in HCN pacemaker channels
Kondapuram, M.; Frieg, B.; Yueksel, S.; Schwabe, T.; Sattler, C.; Lelle, M.; Schweinitz, A.; Schmauder, R.; Benndorf, K.; Gohlke, H.; Kusch, J.
10.1101/2020.09.21.305797 — biophysics — Posted on 2020-09-21
1340 A Multi-center Cross-platform Single-cell RNA Sequencing Reference Dataset
Chen, X.; Yang, Z.; Chen, W.; Zhao, Y.; Farmer, A.; Tran, B.; Furtak, V.; Moos, M.; Xiao, W.; Wang, C.
10.1101/2020.09.20.305474 — bioinformatics — Posted on 2020-09-21
1342 Dissolved organic carbon (DOC) is essential to balance the metabolic demands of four dominant North-Atlantic deepsea sponges
Bart, M. C.; Mueller, B.; Rombouts, T.; van de Ven, C.; Tompkins, G.; Osinga, R.; Brussaard, C.; MacDonald, B.; Engel, A.; Rapp, H. T.; de Goeij, J. M.
10.1101/2020.09.21.305086 — ecology — Posted on 2020-09-21
1345 Cryo-EM structure of S-Trimer, a subunit vaccine candidate for COVID-19
Ma, J.; Su, D.; Huang, X.; Liang, Y.; Ma, Y.; Liang, P.; Zheng, S.
10.1101/2020.09.21.306357 — biophysics — Posted on 2020-09-21
1347 Mechanical impact on the head has an antihypertensive effect
Murase, S.; Sakitani, N.; Maekawa, T.; Yoshino, D.; Konno, A.; Hirai, H.; Saito, T.; Tanaka, S.; Shinohara, K.; Kishi, T.; Yoshikawa, Y.; Sakai, T.; Ayaori, M.; Inanami, H.; Tomiyasu, K.; Ogata, T.; Takashima, A.; Shinohara, M.; Nagao, M.; Sawada, Y.
10.1101/2020.09.21.305706 — bioengineering — Posted on 2020-09-21
1349 Comparative analysis reveals the species-specific genetic determinants of ACE2 required for SARS-CoV-2 entry
Ren, W.; Hu, G.; Zhao, X.; Wang, Y.; Shi, H.; Lan, J.; Zhu, Y.; Wu, J.; Kenney, D. J.; Florian, D.; Tong, Y.; Zhong, J.; Xie, Y.; Wang, X.; Yuan, Z.; Zhou, D.; Zhang, R.; Ding, Q.
10.1101/2020.09.20.297242 — microbiology — Posted on 2020-09-21
1350 A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody
Wu, N. C.; Yuan, M.; Bangaru, S.; Huang, D.; Zhu, X.; Lee, C.-C. D.; Turner, H. L.; Peng, L.; Yang, L.; Nemazee, D.; Ward, A. B.; Wilson, I. A.
10.1101/2020.09.21.305441 — microbiology — Posted on 2020-09-21
1351 Critical Interactions Between the SARS-CoV-2 Spike Glycoprotein and the Human ACE2 Receptor
Taka, E.; Yilmaz, S. Z.; Golcuk, M.; Kilinc, C.; Aktas, U.; Yildiz, A.; Gur, M.
10.1101/2020.09.21.305490 — immunology — Posted on 2020-09-21
1352 The COVID-19 immune landscape is dynamically and reversibly correlated with disease severity
Bolouri, H.; Speake, C.; Skibinski, D.; Long, S. A.; Hocking, A. M.; Campbell, D. J.; Hamerman, J. A.; Malhotra, U.; Buckner, J. H.; BRI COVID-19 Research Team,
10.1101/2020.09.18.303420 — immunology — Posted on 2020-09-21
1353 Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection
Graham, J.; Swarts, J.; Leist, S. R.; Schafer, A.; Menachery, V. D.; Gralinski, L.; Jeng, S.; Miller, D. R.; Mooney, M.; McWeeney, S.; Ferris, M. T.; Pardo-Manuel de Villena, F.; Heise, M. T.; Baric, R. S.; Lund, J. M.
10.1101/2020.09.21.306837 — immunology — Posted on 2020-09-21
1355 Comprehensive characterization of protein-protein interaction network perturbations by human disease mutations
Cheng, F.; Zhao, J.; Wang, Y.; Lu, W.; Liu, Z.; Zhou, Y.; Martin, W.; Wang, R.; Huang, J.; Hao, T.; Yue, H.; Ma, J.; Hou, Y.; Castrillon, J.; Fang, J.; Lathia, J. D.; Keri, R. A.; Lightstone, F. C.; Antman, E. M.; Rabadan, R.; Hill, D. E.; Eng, C.; Vidal, M.; Loscalzo, J.
10.1101/2020.09.18.302588 — systems biology — Posted on 2020-09-21
1360 Phylogenomics reveals multiple introductions and early spread of SARS-CoV-2 into Peru
Juscamayta Lopez, E.; Tarazona, D.; Valdivia Guerrero, F.; Rojas Serrano, N.; Carhuaricra, D.; Maturrano Hernandez, L.; Gavilan Chavez, R.
10.1101/2020.09.14.296814 — genomics — Posted on 2020-09-21
1363 Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection
Dobrindt, K.; Hoagland, D. A.; Seah, C.; Kassim, B.; O'Shea, C.; Iskhakova, M.; Fernando, M.; Deans, P. M.; Powell, S.; Javidfar, B.; Murphy, A.; Peter, C.; Moeller, R.; Fernandez Garcia, M.; Kimura, M.; Iwasawa, K.; Crary, J.; Kotton, D.; Takebe, T.; Huckins, L.; tenOever, B.; Akbarian, S.; Brennand, K. J.
10.1101/2020.09.20.300574 — cell biology — Posted on 2020-09-21
1364 A simple RNA preparation method for SARS-CoV-2 detection by RT-qPCR
Wozniak, A.; Cerda, A.; Ibarra-Henriquez, C.; Sebastian, V.; Armijo, G.; Lamig, L.; Miranda, C.; Lagos, M.; Solari, S.; Guzman, A. M.; Quiroga, T.; Hitschfeld, S.; Riveras, E.; Ferres, M.; Gutierrez, R. A.; Garcia, P.
10.1101/2020.05.07.083048 — molecular biology — Posted on 2020-09-21
1366 Neutralization Assay with SARS-CoV-1 and SARS-CoV-2 Spike Pseudotyped Murine Leukemia Virions
Zheng, Y.; Larragoite, E. T.; Lama, J.; Cisneros, I.; Delgado, J. C.; Slev, P.; Rychert, J.; Innis, E. A.; Williams, E. S. C. P.; Coiras, M.; Rondina, M.; Spivak, A. M.; Planelles, V.
10.1101/2020.07.17.207563 — microbiology — Posted on 2020-09-21
1369 The discovery of a recombinant SARS2-like CoV strain provides insights into SARS and COVID-2019 pandemics
Li, X.; Jin, X.; Chen, S.; Wang, L.; Yau, T. O.; Yang, J.; Hong, Z.; Ruan, J.; Duan, G.; Gao, S.
10.1101/2020.07.22.213926 — bioinformatics — Posted on 2020-09-21
1370 Lung epithelial stem cells express SARS-CoV-2 entry factors: implications for COVID-19
Valyaeva, A. A.; Zharikova, A. A.; Kasianov, A. S.; Vassetzky, Y. S.; Sheval, E. V.
10.1101/2020.05.23.107334 — cell biology — Posted on 2020-09-21
1371 Delayed maturation of the structural brain connectome in neonates with congenital heart disease
Feldmann, M.; Guo, T.; Miller, S. P.; Knirsch, W.; Kottke, R.; Hagmann, C.; Latal, B.; Jakab, A.
10.1101/2020.09.21.306084 — neuroscience — Posted on 2020-09-21
1373 Unique dynamics and exocytosis of single inhibitory synaptic vesicles
Park, C.; Chen, X.; Tian, C.-L.; Park, G. N.; Chenouard, N.; Lee, H.; Yeo, X. Y.; Jung, S.; Bi, G.; Tsien, R. W.; Park, H.
10.1101/2020.09.21.289314 — neuroscience — Posted on 2020-09-21
1374 Engineering protein-specific proteases: targeting active RAS
Chen, Y.; Toth, E. A.; Ruan, B.; Choi, E. J.; Simmerman, R.; Chen, Y.; He, Y.; Wang, R.; Godoy-Ruiz, R.; King, H.; Custer, G.; Gallagher, D. T.; Rozak, D. A.; Soloman, M.; Muro, S.; Weber, D. J.; Orban, J.; Fuerst, T. R.; Bryan, P. N.
10.1101/2020.09.21.303917 — biochemistry — Posted on 2020-09-21
1375 The proportion of periportal mesenchyme to ductal epithelial cells acts as a proliferative rheostat in liver regeneration
Cordero-Espinoza, L.; Kohler, T. N.; Dowbaj, A. M.; Strauss, B.; Sarlidou, O.; Pacini, C.; Dobie, R.; Wilson-Kanamori, J. R.; Butler, R.; Serup, P.; Henderson, N. C.; Hollfelder, F.; Huch, M.
10.1101/2020.09.21.306258 — developmental biology — Posted on 2020-09-21
1377 MICAL2 acts through Arp3B isoform-specific Arp2/3 complexes to destabilize branched actin networks
Galloni, C.; Carra, D.; Abella, J. V. G.; Kjaer, S.; Singaravelu, P.; Barry, D. J.; Kogata, N.; Guerin, C.; Blanchoin, L.; Way, M.
10.1101/2020.09.21.306522 — cell biology — Posted on 2020-09-21
1380 Global Profiling of the Lysine Crotonylome in Different Pluripotent States
Lv, Y.; Bu, C.; Meng, J.; Ward, C.; Volpe, G.; Hu, J.; Jiang, M.; Guo, L.; Chen, J.; Esteban, M. A.; Bao, X.; Cheng, Z.
10.1101/2020.09.21.288167 — cell biology — Posted on 2020-09-21
1385 Inferring intestinal mucosal immune cell associated microbiome species and microbiota-derived metabolites in inflammatory bowel disease
Narasimhan, R. L.; Throm, A. A.; Koshy, J. J.; Saldanha, K. M. R.; Chandranpillai, H.; Lal, R. D.; Kumravat, M.; Kumar K M, A.; Batra, A.; Zhong, F.; Liu, J.
10.1101/2020.09.18.304071 — bioinformatics — Posted on 2020-09-21
1386 Sec22b regulates inflammatory responses by controlling the nuclear translocation of NF-κB
Arango Duque, G.; Dion, R.; Fabie, A.; Descoteaux, J.; Stäger, S.; Descoteaux, A.
10.1101/2020.09.20.305383 — cell biology — Posted on 2020-09-21
1387 Prophage-dependent neighbor predation fosters horizontal gene transfer by natural transformation
Molina-Quiroz, R. C.; Dalia, T. N.; Camilli, A.; Dalia, A. B.; Silva-Valenzuela, C. A.
10.1101/2020.09.19.304527 — microbiology — Posted on 2020-09-21
1388 Acute neonatal oxytocin impacts hippocampal network development and restores adult social memory deficits in a mouse model of autism spectrum disorder.
Bertoni, A.; Schaller, F.; Tyzio, R.; Gaillard, S.; Santini, F.; Xolin, M.; Diabira, D.; Vaidyanathan, R.; Matarazzo, V.; Medina, I.; Hammock, E.; Zhang, J.; Chini, B.; Gaiarsa, J.-L.; Muscatelli, F.
10.1101/2020.09.21.306217 — neuroscience — Posted on 2020-09-21
1391 Epigenetic drift during long-term culture of cells in vitro
Franzen, J.; Georgomanolis, T.; Selich, A.; Kuo, C.-C.; Stoeger, R.; Brant, L.; Mulabdic, M. S.; Fernandez-Rebollo, E.; Grezella, C.; Ostrowska, A.; Begemann, M.; Nikolic, M.; Rath, B.; Ho, A. D.; Rothe, M.; Schambach, A.; Papantonis, A.; Wagner, W.
10.1101/445114 — genomics — Posted on 2020-09-21
1392 Metagenomic insights into ecosystem function in the microbial mats of Blue Holes, Shark Bay
Kindler, G. S.; Wong, H. L. L.; Larkum, A. W. D.; Johnson, M.; MacLeod, F. I.; Burns, B. P.
10.1101/2020.09.18.304444 — microbiology — Posted on 2020-09-21
1394 ImmunoCluster: A computational framework for the non-specialist to profile cellular heterogeneity in cytometry datasets
Opzoomer, J. W.; Timms, J. A.; Blighe, K.; Mourikis, T. P.; Chapuis, N.; Bekoe, R.; Kareemaghay, S.; Nocerino, P.; Apollonio, B.; Ramsay, A. G.; Tavassoli, M.; Harrison, C.; Ciccarelli, F.; Parker, P.; Fontenay, M.; Barber, P.; Arnold, J. N.; Kordasti, S.
10.1101/2020.09.09.289033 — systems biology — Posted on 2020-09-21
1396 Cellular Fitness Phenotypes of Cancer Target Genes in Cancer Therapeutics
George, B.; Mukundan, P. P.; Paul, A. M.; Leitzel, K.; Ali, S. M.; Sandiford, O.; Lipton, A.; Rameshwar, P.; Hortobagyi, G. N.; Pillai, R. M.; Kumar, R.
10.1101/840975 — cancer biology — Posted on 2020-09-21
1397 Crystal structure of full-length cytotoxic necrotizing factor CNFY reveals molecular building blocks for intoxication
Chaoprasid, P.; Lukat, P.; Mühlen, S.; Heidler, T. V.; Gazdag, E. M.; Dong, S.; Bi, W.; Rueter, C.; Kirchenwitz, M.; Steffen, A.; Jansch, L.; Stradal, T.; Dersch, P.; Blankenfeldt, W.
10.1101/2020.04.07.029181 — biochemistry — Posted on 2020-09-21
1406 Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches
Shakya, S.; Gromovsky, A.; Hale, J.; Knudsen, A.; Prager, B.; Wallace, L.; Penalva, L. O.; Ivanova, P.; Brown, H. A.; Kristensen, B.; Rich, J.; Lathia, J.; Brown, J. M.; Hubert, C. G.
10.1101/2020.09.20.304964 — cancer biology — Posted on 2020-09-20
1409 Ligand Modulation of the Conformational Dynamics of the A2A Adenosine Receptor Revealed by Single-Molecule Fluorescence
Fernandes, D. D.; Neale, C.; Gomes, G.-N. W.; Li, Y.; Malik, A.; Pandey, A.; Orazietti, A.; Wang, X.; Ye, L.; Prosser, S.; Gradinaru, C. C.
10.1101/2020.09.20.305425 — biophysics — Posted on 2020-09-20
1410 Improved cortical surface reconstruction using sub-millimeter resolution MPRAGE by image denoising
Tian, Q.; Zaretskaya, N.; Fan, Q.; Ngamsombat, C.; Bilgic, B.; Polimeni, J. R.; Huang, S. Y.
10.1101/2020.09.20.304824 — bioengineering — Posted on 2020-09-20
1412 Fast and easy single-molecule pulldown assay based on agarose microbeads
ZHAO, Q.; SHEN, Y.; LI, X.; TIAN, F.; YU, X.; YOBAS, L.; Park, H.; HUANG, P.
10.1101/2020.09.20.305177 — biochemistry — Posted on 2020-09-20
1413 Proteasome Regulation by Reversible Tyrosine Phosphorylation at the Membrane
Chen, L.; Shu, X.; Chen, Q.; Wei, T.; Wang, X.; Wu, Q.; Wang, H.; Zhang, X.; Liu, X.; Zhang, Y.; Zheng, S.; Huang, L.; Xiao, J.; Jiang, C.; Wang, Z.; Yang, B.; Guo, X.
10.1101/2020.09.20.305532 — biochemistry — Posted on 2020-09-20
1415 Natural selection and the advantage of recombination
Gerrish, P. J.; Galeota-Sprung, B.; Cordero, F.; Sniegowski, P. D.; Colato, A.; Hengartner, N. W.; Vejalla, V.; Chevalier, J.; Ycart, B.
10.1101/2020.08.28.271486 — evolutionary biology — Posted on 2020-09-20
1416 Telmisartan potentiates insulin secretion via ion channels, independent of the AT1 receptor and PPARγ
Zhang, Y.; Liu, T.; Cui, L.; Xue, H.; Zhi, L.; Yang, X.; Yang, H.; Liu, M.; Bai, T.; Liu, Z.; Zhang, M.; Guo, Q.; He, P.; Liu, Y.
10.1101/2020.09.20.305334 — cell biology — Posted on 2020-09-20
1418 The transcription factor ZEB1 regulates stem cell self-renewal and astroglial fate in the adult hippocampus
Gupta, B.; Errington, A. C.; Brabletz, S.; Stemmler, M. P.; Brabletz, T.; Siebzehnrubl, F. A.
10.1101/2020.09.20.305144 — neuroscience — Posted on 2020-09-20
1422 DNA-Origami-Based Fluorescence Brightness Standards for Convenient and Fast Protein Counting in Live Cells
William, N. D.; Landajuela, A.; Kasula, R. K.; Zhou, W.; Powell, J. T.; Xi, Z.; Isaacs, F. J.; Berro, J.; Toomre, D.; Karatekin, E.; Lin, C.
10.1101/2020.09.20.305359 — biophysics — Posted on 2020-09-20
1423 Filopodia rotate and coil by actively generating twist in their actin shaft
Leijnse, N.; Barooji, Y. F.; Verhagen, B.; Wullkopf, L.; Erler, J.; Semsey, S.; Nylandsted, J.; Doostmohammadi, A.; Oddershede, L. B.; Bendix, P. M. M.
10.1101/2020.09.20.305227 — biophysics — Posted on 2020-09-20
1427 Neuroglia Infection by Rabies Virus after Anterograde Virus Spread in Peripheral Neurons
Potratz, M.; Zaeck, L. M.; Weigel, C.; KIein, A.; Mueller, T.; Freuling, C. M.; Finke, S.
10.1101/2020.09.20.305078 — microbiology — Posted on 2020-09-20
1428 What the odor is not: Estimation by elimination
Singh, V.; Tchernookov, M.; Balasubramanian, V.
10.1101/568626 — neuroscience — Posted on 2020-09-20
1431 A digital 3D reference atlas reveals cellular growth patterns shaping the Arabidopsis ovule
Vijayan, A.; Tofanelli, R.; Strauss, S.; Cerrone, L.; Wolny, A.; Strohmeier, J.; Kreshuk, A.; Hamprecht, F.; Smith, R. S.; Schneitz, K.
10.1101/2020.09.19.303560 — plant biology — Posted on 2020-09-20
1432 Evolutionary and Structural Constraints Influencing Apolipoprotein A-I Amyloid Behavior
Gisonno, R. A.; Masson, T.; Ramella, N. A.; Barrera, E. E.; Romanowski, V.; Tricerri, M. A.
10.1101/2020.09.18.304337 — bioinformatics — Posted on 2020-09-20
1436 Restricted constrictors: Space use and habitat selection of native Burmese pythons in Northeast Thailand
Smith, S. N.; Jones, M. D.; Marshall, B. M.; Waengsothorn, S.; Gale, G. A.; Strine, C. T.
10.1101/2020.09.17.302661 — ecology — Posted on 2020-09-20
1437 Strong functional divergence of tropical reef fish assemblages along the global diversity gradient
Parravicini, V.; Bender, M.; Villeger, S.; Leprieur, F.; Donati, G.; Pellissier, L.; Floeter, S.; Rezende, E.; Mouillot, D.; Kulbicki, M.
10.1101/2020.09.18.303008 — ecology — Posted on 2020-09-20
1438 Lymph flow directs rapid neutrophil positioning in the lymph node in infection
Xue, J.; Lin, Y.; Oo, D.; Zhang, J.; Jesus, F.; Zardynezhad, A.; de Almeida, L. G. N.; Young, D.; Dufour, A.; Liao, S.
10.1101/2020.09.20.302075 — immunology — Posted on 2020-09-20
1440 Exogenous sex hormone effects on brain microstructure in women: a diffusion MRI study in the UK Biobank
Nabulsi, L.; Lawrence, K. E.; Santhalingam, V.; Abaryan, Z.; Boyle, C. P.; Villalon-Reina, J. E.; Nir, T. M.; Ba Gari, I.; Zhu, A. H.; Haddad, E.; Muir, A. M.; Jahanshad, N.; Thompson, P. M.
10.1101/2020.09.18.304154 — neuroscience — Posted on 2020-09-20
1441 Regular caffeine intake attenuates REM sleep promotion and sleep quality in healthy men
Weibel, J.; Lin, Y.-S.; Landolt, H.-P.; Berthomier, C.; Brandewinder, M.; Kistler, J.; Rehm, S.; Rentsch, K. M.; Meyer, M.; Borgwardt, S.; Cajochen, C.; Reichert, C. F.
10.1101/2020.09.18.291039 — neuroscience — Posted on 2020-09-20
1442 The Dual Mechanisms of Cognitive Control (DMCC) Project
Braver, T. S.; Kizhner, A.; Tang, R.; Freund, M. C.; Etzel, J. A.
10.1101/2020.09.18.304402 — neuroscience — Posted on 2020-09-20
1443 Challenges in solving structures from radiation-damaged tomograms of protein nanocrystals assessed by simulation
Peck, A.; Yao, Q.; Brewster, A. S.; Zwart, P. H.; Heumann, J. M.; Sauter, N. K.; Jensen, G. J.
10.1101/2020.09.18.298562 — biophysics — Posted on 2020-09-20
1444 Capillary forces drive pioneer transcription factor-mediated DNA condensation
Quail, T.; Golfier, S.; Elsner, M.; Ishihara, K.; Julicher, F.; Brugues, J.
10.1101/2020.09.17.302299 — biophysics — Posted on 2020-09-20
1449 Periplasmic Expression of SpyTagged Antibody Fragments Enables Rapid Modular Antibody Assembly
Hentrich, C.; Kellmann, S.-J.; Putyrski, M.; Cavada, M.; Hanuschka, H.; Knappik, A.; Ylera, F.
10.1101/2020.09.18.302950 — biochemistry — Posted on 2020-09-20
1453 Mechanical compartmentalization of the intestinal organoid enables crypt folding and collective cell migration
Perez-Gonzalez, C.; Ceada, G.; Greco, F.; Matejcic, M.; Gomez-Gonzalez, M.; Castro, N.; Kale, S.; Alvarez-Varela, A.; Roca-Cusachs, P.; Batlle, E.; Vignjevic, D. M.; Arroyo, M.; Trepat, X.
10.1101/2020.09.20.299552 — cell biology — Posted on 2020-09-20
1457 Co-editing PINK1 and DJ-1 genes via AAV-delivered CRISPR/Cas9 system in adult monkey brains elicits classic Parkinsonian phenotypes
Li, H.; Wu, S.; Ma, X.; Li, X.; Cheng, T.; Chen, Z.; Wu, J.; Lv, L.; Li, L.; Xu, L.; Wang, W.; Hu, Y.; Jiang, H.; Yin, Y.; Qiu, Z.; Hu, X.
10.1101/2020.09.19.305003 — neuroscience — Posted on 2020-09-20
1459 Increased upper-limb sensory attenuation with age
Parthasharathy, M.; Mantini, D.; Orban de Xivry, J.-J.
10.1101/2020.09.17.301739 — neuroscience — Posted on 2020-09-20
1460 Advanced diffusion-weighted MRI metrics detect sex differences in aging among 15,000 adults in the UK Biobank
Lawrence, K. E.; Nabulsi, L.; Santhalingam, V.; Abaryan, Z.; Villalon-Reina, J. E.; Nir, T. M.; Ba Gari, I.; Zhu, A. H.; Haddad, E.; Muir, A. M.; Jahanshad, N.; Thompson, P. M.
10.1101/2020.09.18.304345 — neuroscience — Posted on 2020-09-20
1462 Perinatal fentanyl exposure leads to long-lasting impairments in somatosensory circuit function and behavior
Alipio, J.; Haga, C.; Fox, M. E.; Arakawa, K.; Balaji, R.; Cramer, N.; Lobo, M. K.; Keller, A.
10.1101/2020.09.19.304352 — neuroscience — Posted on 2020-09-20
1466 Variability in the diet diversity of catfish highlighted through DNA barcoding
PrasannaKumar, C.; Iyyapparajanarasimapallavan, G.; Ashiq Ur Rahman, M.; Mohanchander, P.; Sudhakar, T.
10.1101/2020.09.18.268888 — zoology — Posted on 2020-09-20
1467 Infectious myonecrosis virus (IMNV) and decapod iridescent virus 1 (DIV1) detected in Penaeus monodonfrom the Indian Ocean
Srisala, J.; Sanguanrut, p.; Laiphrom, S.; Siriwattano, J.; Khudet, J.; Thaiue, D.; Powtongsook, S.; Flegel, T. W.; Sritunyalucksana, K.
10.1101/2020.09.19.304972 — zoology — Posted on 2020-09-20
1468 JSTA: joint cell segmentation and cell type annotation for spatial transcriptomics
Littman, R.; Hemminger, Z.; Foreman, R.; Arneson, D.; Zhang, G.; Gomez-Pinilla, F.; Yang, X.; Wollman, R.
10.1101/2020.09.18.304147 — systems biology — Posted on 2020-09-20
1471 Dose dependent evolutionary game dynamics modulate competitive release in cancer therapy
Farrokhian, N.; Maltas, J.; Ellsworth, P.; Durmaz, A.; Dinh, M.; Hitomi, M.; Kaznatcheev, A.; Marusyk, A.; Scott, J. G.
10.1101/2020.09.18.303966 — cancer biology — Posted on 2020-09-20
1472 Live imaging of breast tumors shows macrophage-dependent induction and TMEM-mediated enrichment of cancer stem cells during metastatic dissemination
Sharma, V. P.; Tang, B.; Wang, Y.; Karagiannis, G. S.; Xue, E. A.; Entenberg, D.; Borriello, L.; Coste, A.; Duran, C. L.; Eddy, R. J.; Kim, G.; Ye, X.; Jones, J. G.; Grunblatt, E.; Agi, N.; Roy, S.; Bandyopadhyaya, G.; Adler, E.; Surve, C. R.; Esposito, D.; Goswami, S.; Guo, W.; Condeelis, J. S.; Wakefield, L. M.; Oktay, M. H.
10.1101/2020.09.18.303388 — cancer biology — Posted on 2020-09-20
1475 Making WAVES in Breedbase: An Integrated Spectral Data Storage and Analysis Pipeline for Plant Breeding Programs
Hershberger, J.; Morales, N.; Simoes, C. C.; Ellerbrock, B.; Bauchet, G.; Mueller, L. A.; Gore, M. A.
10.1101/2020.09.18.278549 — bioinformatics — Posted on 2020-09-20
1477 ORCESTRA: a platform for orchestrating and sharing high-throughput pharmacogenomic analyses
Mammoliti, A.; Smirnov, P.; Nakano, M.; Safikhani, Z.; Ho, C.; Beri, G.; Haibe-Kains, B.
10.1101/2020.09.18.303842 — bioinformatics — Posted on 2020-09-20
1478 Integration of the Drug-Gene Interaction Database (DGIdb) with open crowdsource efforts
Freshour, S.; Kiwala, S.; Cotto, K. C.; Coffman, A. C.; McMichael, J. F.; Song, J.; Griffith, M.; Griffith, O. L.; Wagner, A. H.
10.1101/2020.09.18.301721 — bioinformatics — Posted on 2020-09-20
1481 Dual GRIN lens two-photon endoscopy for high-speed volumetric and deep brain imaging
Chien, Y.-F.; Lin, J.-Y.; Yeh, P.-T.; Hsu, K.-J.; Tsai, Y.-H.; Chen, S.-K.; Chu, S.-W.
10.1101/2020.09.19.304675 — bioengineering — Posted on 2020-09-20
1482 Dimerization mechanism and structural features of human LI-cadherin
Yui, A.; Caaveiro, J. M. M.; Kuroda, D.; Nakakido, M.; Nagatoishi, S.; Goda, S.; Maruno, T.; Uchiyama, S.; Tsumoto, K.
10.1101/2020.09.18.291195 — biochemistry — Posted on 2020-09-20
1484 Cell type-selective secretome profiling in vivo
Wei, W.; Riley, N. M.; Yang, A. C.; Kim, J. T.; Terrell, S. M.; Li, V. L.; Garcia-Contreras, M.; Bertozzi, C. R.; Long, J. Z.
10.1101/2020.09.18.303909 — biochemistry — Posted on 2020-09-20
1488 Stochasticity explains differences in the number of de novo mutations between families
Gilissen, C.; Hampstead, J. E.; Goldmann, J. M.; Wong, W. S. W.; Wilfert, A. B.; Turner, T.; Jonker, M. A.; Bernier, R.; Huynen, M. A.; Eichler, E. E.; Veltman, J. A.; Maxwell, G. L.
10.1101/2020.09.18.303727 — genomics — Posted on 2020-09-20
1491 STAMPede: A Precision Oncology Catalogue of Solid Tumors
Chen, J. W.; Kalantarian, H.; Kunder, C. A.; Zehnder, J. L.; Stehr, H.; Costa, H. A.
10.1101/2020.09.18.290635 — genomics — Posted on 2020-09-20
1492 A De Novo Genome Assembly, Gene Annotation, And Expression Atlas For The Monarch Butterfly Danaus plexippus
Ranz, J. M.; Gonzalez, P.; Clifton, B.; Nazario, N.; Hernandez-Cervantes, P.; Palma-Martinez, M.; Valdivia, D.; Jimenez-Kaufman, A.; Lu, M.; Markow, T. A.; Abreu-Goodger, C.
10.1101/2020.09.19.304162 — genomics — Posted on 2020-09-20
1494 Characterization and expression QTL analysis of TaABI4, a pre-harvest sprouting related gene in wheat
Xiao, C.; Liu, Y.; Chen, W.; Yang, J.; Chen, M.; Watt, C.; Cheng, J.; Wang, Z.; Tan, Z.; Li, M.; Wang, J.
10.1101/2020.09.18.303065 — genetics — Posted on 2020-09-20
1495 Metabolic effects of the schizophrenia-associated 3q29 deletion are sex-specific and uncoupled from behavioral phenotypes
Pollak, R. M.; Purcell, R. H.; Rutkowski, T. P.; Malone, T.; Pachura, K. J.; Bassell, G. J.; Epstein, M. P.; Dawson, P. A.; Smith, M. R.; Jones, D. P.; Zwick, M. E.; the Emory 3q29 Project, ; Warren, S. T.; Caspary, T.; Weinshenker, D.; Mulle, J. G.
10.1101/2020.09.18.303412 — genetics — Posted on 2020-09-20
1505 Development of an MRI Compatible Nasal Drug Delivery Method: Probing Nicotine Addiction Dynamics
Mujica-Parodi, L. R.; Kumar, R.; Wenke, M.; Amgalan, A.; Lithen, A.; Govindarajan, S. T.; Makaryus, R.; Benveniste, H.; Strey, H. H.
10.1101/2020.09.17.302703 — neuroscience — Posted on 2020-09-20
1506 Differential effect of ethanol intoxication on peripheral markers of cerebral injury in murine blunt TBI
li, z.; zhang, j.; halbgebauer, s.; chandrasekar, a.; rehman, r.; ludolph, a. c.; boeckers, t. m.; huber-lang, m.; otto, m.; Roselli, F.; olde Heuvel, f.
10.1101/2020.09.18.303396 — neuroscience — Posted on 2020-09-20
1509 Comparison of multiple tractography methods for reconstruction of the retinogeniculate visual pathway using diffusion MRI
He, J.; Zhang, F.; Xie, G.; Yao, S.; Feng, Y.; Bastos, D. C. A.; Rathi, Y.; Makris, N.; Kikinis, R.; Golby, A. J.; O'Donnell, L. J.
10.1101/2020.09.19.304758 — neuroscience — Posted on 2020-09-20
1511 Orbitofrontal cortex and learning predictions of state transitions
Chan, S. C. Y.; Schuck, N. W.; Lopatina, N.; Schoenbaum, G.; Niv, Y.
10.1101/2020.09.17.302521 — neuroscience — Posted on 2020-09-20
1515 AlzGPS: A Genome-wide Positioning Systems Platform to Catalyze Multi-omics for Alzheimer's Therapeutic Discovery
Zhou, Y.; Fang, J.; Bekris, L.; Kim, Y. H.; Pieper, A. A.; Leverenz, J. B.; Cummings, J.; Cheng, F.
10.1101/2020.09.17.302612 — systems biology — Posted on 2020-09-20
1516 Seed morphology and emergence variability in a conservation collection of Pinus torreyana
Di Santo, L. N.; Polgar, M.; Nies, S.; Hodgkiss, P.; Canning, C. A.; Wright, J. W.; Hamilton, J. A.
10.1101/2020.09.18.303768 — plant biology — Posted on 2020-09-20
1517 Chromogranin A regulates gut permeability via the antagonistic actions of its proteolytic peptides
Muntjewerff, E. M.; Tang, K.; Lutter, L.; Christoffersson, G.; Nicolasen, M. J. T.; Gao, H.; Katkar, G. D.; Das, S.; Beest, M. t.; Ying, W.; Ghosh, P.; El Aidy, S.; Oldenburg, B.; van den Bogaart, G.; Mahata, S. K.
10.1101/2020.09.19.304303 — physiology — Posted on 2020-09-20
1520 MetaFusion: A high-confidence metacaller for filtering and prioritizing RNA-seq gene fusion candidates.
Apostolides, M.; Jiang, Y.; Husic, M.; Siddaway, R.; Hawkins, C.; Turinsky, A.; Brudno, M.; Ramani, A.
10.1101/2020.09.17.302307 — bioinformatics — Posted on 2020-09-20
1525 LiftPose3D, a deep learning-based approach for transforming 2D to 3D pose in laboratory animals
Gosztolai, A.; Gunel, S.; Abrate, M. P.; Morales, D.; Rios, V. L.; Rhodin, H.; Fua, P.; Ramdya, P.
10.1101/2020.09.18.292680 — animal behavior and cognition — Posted on 2020-09-20
1526 The dynamics of spawning acts by a semelparous fish and its associated energetic expenses
Tentelier, C.; Bouchard, C.; Bernardin, A.; Tauzin, A.; Aymes, J.-C.; Lange, F.; Recapet, C.; Rives, J.
10.1101/436295 — ecology — Posted on 2020-09-20
1529 PEA polymer-coated nanotopography delivers solid-state BMP2, enhances mesenchymal stem cell adhesion, prevents bacterial biofilm formation and protects cells from quorum sensing virulence factors
Damiati, L.; Tsimbouri, M.; Ginty, M.; Llopis-Hernandez, V.; Childs, P.; Jayawarna, V.; Xiao, Y.; Burgess, K.; Wells, J.; Sprott, M.; Meek, D.; Li, P.; Oreffo, R.; Nobbs, A.; Ramage, G.; Su, B.; Salmeron-Sanchez, M.; Dalby, M.
10.1101/2020.09.17.302455 — bioengineering — Posted on 2020-09-20
1530 F-domain valency determines outcome of signaling through the angiopoietin pathway
Zhao, Y. T.; Fallas, J. A.; Saini, S.; Ueda, G.; Somasundaram, L.; Zhou, Z.; Xavier, I.; Ehnes, D.; Xu, C.; Carter, L.; Wrenn, S.; Mathieu, J.; Sellers, D. L.; Baker, D.; Ruohola-Baker, H.
10.1101/2020.09.19.304188 — biochemistry — Posted on 2020-09-20
1531 SSnet: A Deep Learning Approach for Protein-Ligand Interaction Prediction
Verma, N.; Qu, X.; Trozzi, F.; Elsaied, M.; Karki, N.; Tao, Y.; Zoltowski, B. D.; Larson, E.; Kraka, E.
10.1101/2019.12.20.884841 — bioinformatics — Posted on 2020-09-20
1533 Imbalanced expression for predicted high-impact, autosomal-dominant variants in a cohort of 3,818 healthy samples
de Klein, N.; van Dijk, F.; Deelen, P.; Urzua, C. G.; Claringbould, A.; Vosa, U.; Verlouw, J. A. M.; Monajemi, R.; 't Hoen, P. A. C.; Sinke, R. J.; BIOS Consortium, ; Swertz, M. A.; Franke, L.
10.1101/2020.09.19.300095 — genomics — Posted on 2020-09-20
1534 Wild flies hedge their thermal preference bets in response to seasonal fluctuations
Akhund-Zade, J.; Yoon, D.; Bangerter, A.; Polizos, N.; Campbell, M. K.; Soloshenko, A.; Zhang, T.; Wice, E.; Albright, A.; Narayanan, A.; Schmidt, P.; Saltz, J.; Ayroles, J.; Klein, M.; Bergland, A.; de Bivort, B.
10.1101/2020.09.16.300731 — evolutionary biology — Posted on 2020-09-20
1535 SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism
Shi, M.; Wang, L.; Fontana, P.; Vora, S.; Zhang, Y.; Fu, T.-M.; Lieberman, J.; Wu, H.
10.1101/2020.09.18.302901 — cell biology — Posted on 2020-09-20
1536 A step-by-step sequence-based analysis of virome enrichment protocol for freshwater and sediment samples
Pinto, F.; Zolfo, M.; Beghini, F.; Armanini, F.; Asnicar, F.; Silverj, A.; Boscaini, A.; Salmaso, N.; Segata, N.
10.1101/2020.09.17.302836 — microbiology — Posted on 2020-09-20
1537 Zika virus NS3 protease and its cellular substrates
Dabrowska, A.; Milewska, A.; Ner-Kluza, J.; Suder, P.; Pyrc, K.
10.1101/2020.09.18.303867 — microbiology — Posted on 2020-09-20
1541 Metagenomic insights into ecosystem function in the microbial mats of Blue Holes, Shark Bay
Kindler, G. S.; Wong, H. L. L.; Larkum, A. W. D.; Johnson, M.; MacLeod, F. I.; Burns, B. P.
10.1101/2020.09.18.304444 — microbiology — Posted on 2020-09-20
1542 Using cortical neuron markers to target cells in the dorsal cochlear nucleus
Malfatti, T.; Ciralli, B.; Hilscher, M. M.; Edwards, S. J.; Kullander, K.; Leao, R. N.; Leao, K. E.
10.1101/2020.09.19.304550 — neuroscience — Posted on 2020-09-20
1544 A robust mean and variance test with application tohigh-dimensional phenotypes
Staley, J. R.; Windmeijer, F.; Suderman, M.; Lyon, M. S.; Davey Smith, G.; Tilling, K.
10.1101/2020.02.06.926584 — bioinformatics — Posted on 2020-09-20
1546 PARP inhibition in Ewing sarcoma: impact of germline DNA damage repair defects and activation of immunoregulatory pathways
Maurer, L. M.; Venier, R. E.; Mukherjee, E.; Julian, C. M.; Daley, J. D.; Bailey, N. G.; Jacobs, M. F.; Kumar-Sinha, C.; Raphel, H.; Weiss, K.; Janeway, K. A.; Mody, R.; Lucas, P. C.; McAllister-Lucas, L. M.; Bailey, K. M.
10.1101/2020.09.18.304238 — cancer biology — Posted on 2020-09-19
1548 F-domain valency determines outcome of signaling through the angiopoietin pathway
Zhao, Y. T.; Fallas, J. A.; Saini, S.; Ueda, G.; Somasundaram, L.; Zhou, Z.; Xavier, I.; Ehnes, D.; Xu, C.; Carter, L.; Wrenn, S.; Mathieu, J.; Sellers, D. L.; Baker, D.; Ruohola-Baker, H.
10.1101/2020.09.19.304188 — biochemistry — Posted on 2020-09-19
1549 Primary sex determination in chickens depends on DMRT1 dosage, but gonadal sex does not determine secondary sexual characteristics in adult birds
Ioannidis, J.; Taylor, G.; Zhao, D.; Liu, L.; Idoko-Akoh, A.; Gong, D.; Lovell-Badge, R.; Guioli, S.; McGrew, M.; Clinton, M.
10.1101/2020.09.18.303040 — developmental biology — Posted on 2020-09-19
1550 Msp1/ATAD1 restores mitochondrial function in Zellweger Spectrum Disease
Nuebel, E.; Morgan, J. T.; Fogarty, S.; Winter, J. M.; Lettlova, S.; Berg, J. A.; Chen, Y.-C.; Kidwell, C. U.; Maschek, J. A.; Clowers, K. J.; Argyriou, C.; Chen, L.; Wittig, I.; Cox, J. E.; Roh-Johnson, M.; Braverman, N.; Steinberg, S. J.; Gygi, S. P.; Rutter, J.
10.1101/2020.09.19.303826 — cell biology — Posted on 2020-09-19
1551 Antisense oligonucleotides target a nearly invariant structural element from the SARS-CoV-2 genome and drive RNA degradation
Lulla, V.; Wandel, M. P.; Bandyra, K. J.; Dendooven, T.; Yang, X.; Doyle, N.; Oerum, S.; O'Rourke, S.; Randow, F.; Maier, H. J.; Scott, W.; Ding, Y.; Firth, A.; Bloznelyte, K.; Luisi, B.
10.1101/2020.09.18.304139 — molecular biology — Posted on 2020-09-19
1554 Potent activation of SARM1 by NMN analogue VMN underlies vacor neurotoxicity
Loreto, A.; Angeletti, C.; Gilley, J.; Arthur-Farraj, P.; Merlini, E.; Amici, A.; Desrochers, L. M.; Wang, Q.; Orsomando, G.; Coleman, M. P.
10.1101/2020.09.18.304261 — neuroscience — Posted on 2020-09-19
1555 A Comprehensive Study of Synthetic DNA Preservation for DNA Data Storage
Organick, L. W.; Nguyen, B. H.; McAmis, R.; Chen, W. D.; Kohll, A. X.; Dumas Ang, S.; Grass, R. N.; Ceze, L. H.; Strauss, K.
10.1101/2020.09.19.304014 — synthetic biology — Posted on 2020-09-19
1558 Nanomechanical phenotypes in cMyBP-C mutants that cause hypertrophic cardiomyopathy
Suay-Corredera, C.; Pricolo, M. R.; Velazquez-Carreras, D.; Pimenta-Lopes, C.; Sanchez-Ortiz, D.; Urrutia-Irazabal, I.; Vilches, S.; Dominguez, F.; Frisso, G.; Monserrat, L.; Garcia-Pavia, P.; Herrero-Galan, E.; Alegre-Cebollada, J.
10.1101/2020.09.19.304618 — biophysics — Posted on 2020-09-19
1561 The CD28-transmembrane domain mediates chimeric antigen receptor heterodimerization with CD28
Muller, Y.; Nguyen, D.; Ferreira, L. M. R.; Ho, P.; Raffin, C.; Beltran Valencia, R.; Congrave-Wilson, Z.; Roth, T.; Eyquem, J.; Van Gool, F.; Marson, A. M. R.; Wells, J. A.; Bluestone, J. A.; Tang, Q.
10.1101/2020.09.18.296913 — bioengineering — Posted on 2020-09-19
1568 Protein Abundance Prediction Through Machine Learning Methods
Ferreira, M. A. d. M.; Ventorim, R. Z.; de Almeida, E. L. M.; Silveira, S. d. A.; da Silveira, W. B.
10.1101/2020.09.17.302182 — systems biology — Posted on 2020-09-19
1569 Anti-androgens induce Rab11a-exosome secretion in prostate cancer by suppressing amino acid-sensitive PAT4-mTORC1 signalling
McCormick, K.; Sanitt, P.; Fan, S.-J.; Mason, J. D.; Harris, A. L.; Hamdy, F.; Verrill, C.; Bryant, R. J.; Goberdhan, D. C. I.
10.1101/2020.09.18.300137 — cancer biology — Posted on 2020-09-19
1570 YY1 cistrome analysis uncovers an essential requirement of the YY1:BRD4-PFKP regulatory axis for promoting tumorigenesis of castration-resistant prostate cancer
Cai, L.; Xu, C.; Tsai, Y.-H.; Galbo, P.; Gong, W.; Storey, A.; Xu, Y.; Byrum, S.; Whang, Y.; Parker, J.; Mackintosh, S.; Edmondson, R.; Tackett, A.; Huang, J.; Zheng, D.; Earp, S.; Wang, G. G.
10.1101/2020.09.17.302596 — cancer biology — Posted on 2020-09-19
1574 Consistent ultra-long DNA sequencing with automated slow pipetting
Prall, T. M.; Neuman, E. K.; Karl, J. A.; Shortreed, C. G.; Baker, D. A.; Bussan, H. E.; Wiseman, R. W.; O'Connor, D. H.
10.1101/2020.09.18.302471 — genomics — Posted on 2020-09-19
1575 Autophagy inhibition rescues structural and functional defects caused by the loss of mitochondrial chaperone Hsc70-5/mortalin in Drosophila
Zhu, J.-y.; Hannan, S. B.; Draeger, N. M.; Vereshchagina, N.; Krahl, A.-C.; Fu, Y.; Elliott, C.; Han, Z.; Jahn, T. R.; Rasse, T. M.
10.1101/2020.09.17.302141 — genetics — Posted on 2020-09-19
1576 Fetal alleles predisposing to metabolically favourable adiposity are associated with higher birth weight
Thompson, W. D.; Beaumont, R. N.; Kuang, A.; Warrington, N. M.; Ji, Y.; Tyrrell, J.; Wood, A. R.; Scholtens, D.; Knight, B. R.; Evans, D. M.; Lowe, B. L.; Santorelli, G.; Azad, R.; Mason, D.; Hattersley, A. T.; Frayling, T.; Yaghootkar, H.; Borges, M. C.; Lawlor, D. A.; Freathy, R. M.
10.1101/2020.09.17.302208 — genetics — Posted on 2020-09-19
1578 Prey-Driven Behavioral Habitat Use in a Low-Energy Ambush Predator
Tutterow, A. M.; Hoffman, A. S.; Buffington, J. L.; Truelock, Z. T.; Peterman, W. E.
10.1101/2020.09.17.301697 — ecology — Posted on 2020-09-19
1586 Dual strategies in human confidence judgments
Bertana, A.; Chetverikov, A.; van Bergen, R. S.; Ling, S.; Jehee, J.
10.1101/2020.09.17.299743 — neuroscience — Posted on 2020-09-19
1587 C-terminal-dependent control of EAAT2 signaling, corticostriatal synaptic glutamate clearance and spontaneous motor activity in mice with hypokinesia
Hirschberg, S.; Dvorzhak, A.; Rasooli-Nejad, S. M. A.; Angelov, S.; Kirchner, M.; Mertins, P.; Lättig-Tünnemann, G.; Harms, C.; Schmitz, D.; Grantyn, R.
10.1101/2020.09.17.302158 — neuroscience — Posted on 2020-09-19
1588 An accurate aging clock developed from the largest dataset of microbial and human gene expression reveals molecular mechanisms of aging
Gopu, V.; Cai, Y.; Krishnan, S.; Rajagopal, S.; Camacho, F.; Toma, R.; Torres, P. J.; Vuyisich, M.; Perlina, A.; Banavar, G. S.; Tily, H.
10.1101/2020.09.17.301887 — systems biology — Posted on 2020-09-19
1590 Design of Biologically Active Binary Protein 2D Materials
Ben-Sasson, A. J.; Watson, J.; Sheffler, W.; Johnson, M. C.; Bittleston, A.; Somasundaram, L.; Decarreau, J.; Jiao, F.; Chen, J.; Drabek, A. A.; Jarrett, S. M.; Kollman, J. M.; Blacklow, S. C.; De Yoreo, J. J.; Ruohola-Baker, H.; Derivery, E.; Baker, D.
10.1101/2020.09.19.304253 — synthetic biology — Posted on 2020-09-19
1592 Cardiac overexpression of microRNA-7 is associated with adverse cardiac remodeling
Gupta, M. K.; Sahu, A.; Wang, X.; Martelli, E. E.; Stenson, K.; Withrow, C.; Naga Prasad, S. V.
10.1101/2020.09.17.302224 — physiology — Posted on 2020-09-19
1593 Diversity Across the Pancreatic Ductal Adenocarcinoma Disease Spectrum Revealed by Network-Anchored Functional Genomics
Rose, J. L.; Srinivasan, S.; Yao, W.; Seth, S.; Peoples, M.; Machado, A.; Li, C.-Y.; Ho, I. L.; Lee, J. J.; Guerrero, P. A.; Kim, E.; Syed, M.; Daniele, J. R.; Deem, A.; Kim, M.; Bristow, C. A.; Koay, E. J.; Genovese, G.; Viale, A.; Heffernan, T. P.; Maitra, A.; Hart, T.; Carugo, A.; Draetta, G. F.
10.1101/2020.09.17.302034 — cancer biology — Posted on 2020-09-19
1594 The antiangiogenic compound axitinib demonstrates low toxicity and anti-tumoral effects against medulloblastoma
Pagnuzzi-Boncompagni, M.; Picco, V.; Vial, V.; Planas-Bielsa, V.; Vandenberghe, A.; Grepin, R.; Durivault, J.; Montemagno, C.; Martial, S.; Doyen, J.; Gavard, J.; Pages, G.
10.1101/2020.09.18.301028 — cancer biology — Posted on 2020-09-19
1598 A Bioelectric Neural Interface Towards Intuitive Prosthetic Control For Amputees
Nguyen, A. T.; Xu, J.; Jiang, M.; Luu, D. K.; Wu, T.; Tam, W.-k.; Zhao, W.; Drealan, M. W.; Overstreet, C. K.; Zhao, Q.; Cheng, J.; Keefer, E. W.; Yang, Z.
10.1101/2020.09.17.301663 — bioengineering — Posted on 2020-09-19
1599 Insulin inhibits protein phosphatase 2A to impair β-adrenergic receptor function
Sahu, A.; Sun, Y.; Mukherjee, S.; Witherow, C.; Stenson, K.; Tesmer, J. J. G.; Mohan, M.; Naga Prasad, S. N.
10.1101/2020.09.17.302448 — biochemistry — Posted on 2020-09-19
1602 Quantifying dispersal variability among nearshore marine populations
Catalano, K. A.; Dedrick, A. G.; Stuart, M. R.; Puritz, J. B.; Montes, H. R.; Pinsky, M. L.
10.1101/2020.09.17.299941 — ecology — Posted on 2020-09-19
1603 Long-term (1990-2019) monitoring of tropical moist forests dynamics
Vancutsem, C.; Achard, F.; Pekel, J.-F.; Vieilledent, G.; Carboni, S.; Simonetti, D.; Gallego, J.; Aragao, L.; Nasi, R.
10.1101/2020.09.17.295774 — ecology — Posted on 2020-09-19
1604 Phytophthora sojae effector Avr1d functions as E2 competitor and inhibits ubiquitination activity of GmPUB13 to facilitate infection
Lin, Y.; Hu, Q.; Zhou, J.; Yin, W.-X.; Yao, D.; Shao, Y.; Zhao, Y.; Guo, B.; Xia, Y.; Chen, Q.; Wang, Y.; Ye, W.; Xie, Q.; Tyler, B. M.; Xing, W.; Wang, Y.
10.1101/2020.09.19.304535 — microbiology — Posted on 2020-09-19
1606 Identification of trans-AT polyketide clusters in two marine bacteria reveals cryptic similarities between distinct symbiosis factors
Kacar, D.; Canedo, L. M.; Rodriguez, P.; Gonzalez, E.; Galan, B.; Schleissner, C.; Leopold-Messer, S.; Piel, J.; Cuevas, C.; de la Calle, F.; Garcia, J. L.
10.1101/2020.09.18.303172 — microbiology — Posted on 2020-09-19
1607 Functional diversity of microboring Ostreobium algae isolated from corals
Masse, A.; Tribollet, A.; Meziane, T.; Bourguet-Kondracki, M.-L.; Yepremian, C.; Seve, C.; Thiney, N.; Longeon, A.; Coute, A.; Domart-Coulon, I.
10.1101/2020.09.18.303545 — microbiology — Posted on 2020-09-19
1608 Long-term cellulose enrichment selects for highly cellulolytic consortia and competition for public goods
Lewin, G. R.; Davis, N. M.; McDonald, B. R.; Book, A. J.; Chevrette, M. G.; Suh, S.; Boll, A.; Currie, C. R.
10.1101/2020.09.18.304485 — microbiology — Posted on 2020-09-19
1609 Metagenomic insights into ecosystem function in the microbial mats of Blue Holes, Shark Bay
Kindler, G. S.; Burns, B. P.; Wong, H. L. L.; Larkum, A. W. D.; Johnson, M.; MacLeod, F. I.
10.1101/2020.09.18.304444 — microbiology — Posted on 2020-09-19
1610 Mechanism of selectivity reveals novel antifolate drug interactions
Kordus, S. L.; Lamont, E. A.; Howe, M. D.; Bauman, A. A.; McCue, W.; Finzel, B.; Baughn, A. D.
10.1101/2020.09.18.304022 — microbiology — Posted on 2020-09-19
1614 Broad frequency sensitivity and complex neural coding in the larval zebrafish auditory system
Poulsen, R. E.; Scholz, L. A.; Constantin, L.; Favre-Bulle, I. A.; Vanwalleghem, G.; Scott, E. K.
10.1101/2020.09.17.301242 — neuroscience — Posted on 2020-09-19
1617 Demyelination induces selective vulnerability of inhibitory networks in multiple sclerosis
Zoupi, L.; Booker, S. A.; Eigel, D.; Werner, C.; Kind, P. C.; Spires-Jones, T.; Newland, B.; Williams, A.
10.1101/2020.09.17.302042 — neuroscience — Posted on 2020-09-19
1621 Heterologous production of 1-tuberculosinyladenosine in Mycobacterium kansasii models pathoevolution towards the transcellular lifestyle of Mycobacterium tuberculosis.
Ghanem, M.; Dube, J.-Y.; Wang, J.; McIntosh, F.; Houle, D.; Domenech, P.; Reed, M. B.; Raman, S.; Buter, J.; Minnaard, A. J.; Moody, B.; Behr, M. A.
10.1101/2020.04.25.060590 — microbiology — Posted on 2020-09-19
1622 Using cortical neuron markers to target cells in the dorsal cochlear nucleus
Malfatti, T.; Ciralli, B.; Hilscher, M. M.; Edwards, S. J.; Kullander, K.; Leao, R. N.; Leao, K. E.
10.1101/2020.09.19.304550 — neuroscience — Posted on 2020-09-19
1623 Optogenetic evaluation of the ability of different cutaneous C-fiber afferents to evoke aversive behaviors
Warwick, C. A.; Cassidy, C.; Hachisuka, J.; Wright, M. C.; Baumbauer, K. M.; Adelman, P. C.; Le, K. H.; Smith, K. M.; Ross, S. E.; Koerber, H. R.
10.1101/2020.09.17.296384 — neuroscience — Posted on 2020-09-19
1624 The gut microbiome and its metabolites are necessary for morphine reward
Hofford, R. S.; Mervosh, N. L.; Euston, T. J.; Meckel, K. R.; Orr, A. T.; Kiraly, D. D.
10.1101/2020.09.17.302570 — neuroscience — Posted on 2020-09-19
1625 Genomic stability of Self-inactivating Rabies
Ciabatti, E.; Gonzalez-Rueda, A.; de Malmazet, D.; Lee, H.; Morgese, F.; Tripodi, M.
10.1101/2020.09.19.304683 — neuroscience — Posted on 2020-09-19
1626 "Organoid-in-a-column" coupled on-line with liquid chromatography-mass spectrometry
Kogler, S.; Harrison, S.; Skottvoll, F. S.; Aizenshtadt, A.; Abadpour, S.; Krauss, S.; Scholz, H.; Sullivan, G.; Lundanes, E.; Wilson, S. R.
10.1101/2020.09.08.282756 — bioengineering — Posted on 2020-09-19
1628 Chronic lithium treatment alters the excitatory/inhibitory balance of synaptic networks and reduces mGluR5-PKC signaling
Khayachi, A.; Ase, A. R.; Liao, C.; Kamesh, A.; Kuhlmann, N.; Schorova, L.; Chaumette, B.; Dion, P.; Alda, M.; Rouleau, G. A.; Milnerwood, A. J.
10.1101/2020.09.18.303578 — neuroscience — Posted on 2020-09-19
1629 Modern Machine Learning: Partition & Vote
Priebe, C. E.; Vogelstein, J.; Engert, F.; White, C. M.
10.1101/2020.04.29.068460 — neuroscience — Posted on 2020-09-19
1630 annoFuse: an R Package to annotate, prioritize, and interactively explore putative oncogenic RNA fusions
Gaonkar, K. S.; Marini, F.; Rathi, K. S.; Jain, P.; Zhu, Y.; Chimicles, N. A.; Brown, M. A.; Naqvi, A. S.; Zhang, B.; Storm, P. B.; Maris, J. M.; Resnick, A. C.; Raman, P.; Strauch, K.; Taroni, J. N.; Rokita, J. L.
10.1101/839738 — bioinformatics — Posted on 2020-09-19
1632 Phylogeographic and phylodynamic approaches to epidemiological hypothesis testing
Dellicour, S.; Lequime, S.; Vrancken, B.; Gill, M. S.; Bastide, P.; Gangavarapu, K.; Matteson, N. L.; Tan, Y.; du Plessis, L.; Fisher, A. A.; Nelson, M. I.; Gilbert, M.; Suchard, M. A.; Andersen, K. G.; Grubaugh, N. D.; Pybus, O. G.; Lemey, P.
10.1101/788059 — evolutionary biology — Posted on 2020-09-19
1636 Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients
Miller-Vedam, L. E.; Bräuning, B.; Popova, K. D.; Schirle Oakdale, N. T.; Bonnar, J. L.; Prabu, J. R.; Boydston, E. A.; Sevillano, N.; Shurtleff, M. J.; Stroud, R. M.; Craik, C. S.; Schulman, B.; Frost, A.; Weissman, J. S.
10.1101/2020.09.02.280008 — biophysics — Posted on 2020-09-19
1640 A Global Temporal Genetic Program for Neural Circuit Formation
Jain, S.; Lin, Y.; Kurmangaliyev, Y.; Mirshahidi, P.; Parrington, B.; Zipursky, S. L.
10.1101/2020.09.18.304410 — neuroscience — Posted on 2020-09-19
1641 A neuroskeletal atlas of the mouse limb
Lorenz, M. R.; Brazill, J. M.; Beeve, A.; Shen, I.; Scheller, E. L.
10.1101/2020.09.18.303958 — systems biology — Posted on 2020-09-19
1642 ISOTOPE: ISOform-guided prediction of epiTOPEs in cancer
Trincado, J. L.; Reixachs-Sole, M.; Perez-Granado, J.; Fugmann, T.; Yokota, J.; Sanz, F.; Eyras, E.
10.1101/2020.06.18.159244 — bioinformatics — Posted on 2020-09-19
1643 CIB2 regulates autophagy via Rheb-mTORC1 signaling axis
Sethna, S. S.; Bernstein, S. L.; Jian, X.; Riazuddin, S.; Randazzo, P. A.; Riazuddin, S.; Ahmed, Z. M.
10.1101/2020.09.18.302265 — cell biology — Posted on 2020-09-19
1644 Microbiome-related aspects of locust density-dependent phase transition
Lavy, O.; Lewin-Epstein, O.; Bendett, Y.; Gophna, U.; Gefen, E.; Hadany, L.; Ayali, A.
10.1101/2020.09.17.301010 — microbiology — Posted on 2020-09-19
1651 DNA Methylation Reprogramming during Sex Determination and Transition in Zebrafish
Wang, x.; Ma, x.; Wei, g.; Ma, W.; Zhang, z.; Chen, x.; Gao, L.; Liu, z.; Yuan, y.; Yi, l.; Wang, J.; Tokumoto, T.; Huang, J.; Chen, d.; Zhang, j.; Liu, J.
10.1101/2020.09.17.301580 — developmental biology — Posted on 2020-09-19
1652 Dissecting the DNA binding landscape and gene regulatory network of p63 and p53
Riege, K.; Kretzmer, H.; Sahm, A.; McDade, S. S.; Hoffmann, S.; Fischer, M.
10.1101/2020.06.11.145540 — genomics — Posted on 2020-09-18
1653 Comparative Analysis of Gut Microbiome in Individuals of the Old Civilization of Caral-Supe Based on Data from 16S rRNA and ITS region
Vasquez-Dominguez, A.; Jaramillo-Valverde, L.; Levano, K. S.; Novoa-Bellota, P.; Machaguay-Romero, M.; Garcia-de-la-Guarda, R.; Cano, R. J.; Shady Solis, R.; Guio, H.
10.1101/2020.04.24.060582 — genetics — Posted on 2020-09-18
1655 Infection with CagA+ Helicobacter pylori induces epithelial to mesenchymal transition in human cholangiocytes
Thanaphongdecha, P.; Speigh, S.; Tanno, W. I.; Mann, V. H.; Chamgramol, Y.; Pairojkul, C.; Fox, J. G.; Suttiprapa, S.; Sripa, B.; Brindley, P. J.
10.1101/2020.04.28.066324 — molecular biology — Posted on 2020-09-18
1656 A meta-analysis and experiment assessing phage-based FMDV vaccine
Yang, N.; chen, c.; Wu, P.; Wang, Y.; Xu, M.; Zhang, Y.; Mingguo Xu, Yunfeng Zhang,
10.1101/2020.09.18.303107 — immunology — Posted on 2020-09-18
1658 Perfusion MRI using endogenous deoxyhemoglobin as a contrast agent: preliminary data
Poublanc, J.; Sobczyk, O.; Shafi, R.; Uludag, K.; Wood, J.; Vu, C.; Dharmakumar, R.; Fisher, J. A.; Mikulis, D. J.
10.1101/2020.08.21.255802 — neuroscience — Posted on 2020-09-18
1660 Genetic design automation for autonomous formation of multicellular shapes from a single cell progenitor
Appleton, E.; Mehdipour, N.; Daifuku, T.; Briers, D.; Haghighi, I.; Moret, M.; Chao, G.; Wannier, T.; Chiappino-Pepe, A.; Huang, J.; Belta, C.; Church, G. M.
10.1101/807107 — synthetic biology — Posted on 2020-09-18
1663 Proteome-wide prediction of bacterial carbohydrate-binding proteins as a tool for understanding commensal and pathogen colonisation of the vaginal microbiome
Bonnardel, F.; Haslam, S. M.; Dell, A.; Feizi, T.; Liu, Y.; Tajadura-Ortega, V.; Akune, Y.; Sykes, L.; Bennett, P. R.; MacIntyre, D. A.; Lisacek, F.; Imberty, A.
10.1101/2020.09.10.291781 — bioinformatics — Posted on 2020-09-18
1666 Haplotype-resolved genome assembly enables gene discovery in the red palm weevil Rhynchophorus ferrugineus
Dias, G. B.; Altammami, M. A.; El-Shafie, H. A. F.; Alhoshani, F. M.; Al-Fageeh, M. B.; Bergman, C. M.; Manee, M. M.
10.1101/2020.08.30.273383 — genomics — Posted on 2020-09-18
1667 Expansion dynamics and marginal climates drive adaptation across geographic ranges
Bontrager, M.; Usui, T.; Lee-Yaw, J. A.; Anstett, D. N.; Branch, H. A.; Hargreaves, A. L.; Muir, C. D.; Angert, A. L.
10.1101/2020.08.22.262915 — evolutionary biology — Posted on 2020-09-18
1668 Ambient light and mimicry as drivers of wing transparency in Lepidoptera
Arias, M.; Barbut, J.; Rougerie, R.; Dutry, M.; Kohler, M.; Laulan, B.; Paillard, C.; Berthier, S.; Andraud, C.; Elias, M.; Gomez, D.
10.1101/2020.06.26.172932 — evolutionary biology — Posted on 2020-09-18
1672 BRD4-mediated repression of p53 is a target for combination therapy in AML
Latif, A.-L.; Newcombe, A.; Li, S.; Gilroy, K.; Robertson, N.; Lei, X.; Stewart, H.; Cole, J.; Terradas, M. T.; Rishi, L.; McGarry, L.; McKeeve, C.; Reid, C.; Clark, W.; Campos, J.; Kirschner, K.; Davis, A. E.; Lopez, J.; Sakamaki, J.-I.; Morton, J.; Ryan, K. M.; Tait, S.; Abraham, S.; Holyoake, T.; Higgens, B.; Huang, X.; Blyth, K.; Copland, M.; Chevassut, T.; Keeshan, K.; Adams, P. D.
10.1101/2020.09.16.291930 — cell biology — Posted on 2020-09-18
1674 Cocculus hirsutus -derived phytopharmaceutical drug has potent anti-dengue activity
Poddar, A.; Shukla, R.; Beesetti, H.; Arora, U.; Rajpoot, R. K.; Shanmugam, R. K.; Palla, S.; Nayyar, K.; Singh, D.; Singamaneni, V.; Gupta, P.; Gupta, A. P.; Gairola, S.; Bedi, Y. S.; Jain, T.; Vashishta, B.; Patil, R.; Madan, H.; Madan, S.; Kalra, R.; Sood, R.; Vishwakarma, R.; Lal, A. A.; Khanna, N.
10.1101/2020.09.18.303149 — microbiology — Posted on 2020-09-18
1677 The relationship between resting-state functional connectivity, antidepressant discontinuation and depression relapse
Berwian, I. M.; Wenzel, J. G.; Kuehn, L.; Schnuerer, I.; Kasper, L.; Veer, I. M.; Seifritz, E.; Stephan, K. E.; Walter, H.; Huys, Q. J. M.
10.1101/2020.02.06.937268 — neuroscience — Posted on 2020-09-18
1679 Actin-inspired feedback couples speed and persistence in a Cellular Potts Model of cell migration
Wortel, I. M. N.; Niculescu, I.; Kolijn, P. M.; Gov, N.; de Boer, R. J.; Textor, J.
10.1101/338459 — biophysics — Posted on 2020-09-18
1680 Determination of the molecular reach of the protein tyrosine phosphatase SHP-1
Clemens, L.; Kutuzov, M.; Bayer, K. V.; Goyette, J.; Allard, J.; Dushek, O.
10.1101/2020.09.04.283341 — biophysics — Posted on 2020-09-18
1682 ISOTOPE: ISOform-guided prediction of epiTOPEs in cancer
Trincado, J. L.; Reixachs-Sole, M.; Perez-Granado, J.; Fugmann, T.; Yokota, J.; Sanz, F.; Eyras, E.
10.1101/2020.06.18.159244 — bioinformatics — Posted on 2020-09-18
1686 Discovery and biosynthesis of clostyrylpyrones from the obligate anaerobe Clostridium roseum
Li, J. S.; Du, Y.; Gu, D.; Cai, W.; Green, A.; Ng, S.; Leung, A.; Del Rio Flores, A.; Zhang, W.
10.1101/2020.08.10.245514 — biochemistry — Posted on 2020-09-18
1688 Genome-Wide Mapping of Human DNA Replication by Optical Replication Mapping Supports a Stochastic Model of Eukaryotic Replication
Wang, W.; Klein, K.; Proesmans, K.; Yang, H.; Marchal, C.; Zhu, X.; Borrman, T.; Hastie, A.; Weng, Z.; Bechhoefer, J.; Chen, C.-L.; Gilbert, D. M.; Rhind, N.
10.1101/2020.08.24.263459 — genomics — Posted on 2020-09-18
1689 Genomic approach for conservation and the sustainable management of endangered species of the Amazon
Fazzi-Gomes, P.; Aguiar, J.; Cabral, G. F.; Marques, D.; Palheta, H.; Moreira, F.; Rodrigues, M.; Cavalcante, R.; Souza, J.; Silva, C.; Hamoy, I.; Santos, S.
10.1101/2020.09.18.303115 — genomics — Posted on 2020-09-18
1691 Dynamics of alternative splicing during somatic cell reprogramming reveals functions for RNA-binding proteins CPSF3, hnRNP UL1 and TIA1
Vivori, C.; Papasaikas, P.; Stadhouders, R.; Di Stefano, B.; Berenguer Balaguer, C.; Generoso, S.; Mallol, A.; Sardina, J. L.; Payer, B.; Graf, T.; Valcarcel, J.
10.1101/2020.09.17.299867 — molecular biology — Posted on 2020-09-18
1692 Diminished adherence of Biomphalaria glabrata embryonic cell line to sporocysts of Schistosoma mansoni following programmed knockout of the allograft inflammatory factor
Coelho, F. S.; Rodpai, R.; Miller, A.; Karinshak, S. E.; Mann, V. H.; dos Santos Carvalho, O.; Caldeira, R. L.; de Moraes Mourao, M.; Brindley, P. J.; Tanno, W. I.
10.1101/2020.04.07.029629 — molecular biology — Posted on 2020-09-18
1695 Splice switching oligonucleotide mediated gene knockdown in B cells and plasma cells
Delpy, L.; Marchalot, A.; Lambert, J.-M.; Boyer, F.; Pollet, J.; Cook-Moreau, J.; Feuillard, J.; Faumont, N.
10.1101/2020.09.18.302984 — immunology — Posted on 2020-09-18
1696 Thalamus and claustrum control parallel layer 1 circuits in retrosplenial cortex
Brennan, E. K.; Jedrasiak-Cape, I.; Kailasa, S.; Rice, S. P.; Sudhakar, S. K.; Ahmed, O. J.
10.1101/2020.09.17.300863 — neuroscience — Posted on 2020-09-18
1698 Distributed sensory coding by cerebellar complex spikes in units of cortical segments
Michikawa, T.; Yoshida, T.; Kuroki, S.; Ishikawa, T.; Kakei, S.; Itohara, S.; Miyawaki, A.
10.1101/2020.09.18.301564 — neuroscience — Posted on 2020-09-18
1699 Local circuit allowing hypothalamic control of hippocampal area CA2 activity and consequences for CA1
Robert, V.; Therreau, L.; Huang, A. J. Y.; Boehringer, R.; Polygalov, D.; McHugh, T. J.; Chevaleyre, V.; Piskorowski, R. A.
10.1101/2020.09.18.303693 — neuroscience — Posted on 2020-09-18
1700 Mutations on a novel brain-specific isoform of PGC1α leads to extensive upregulation of neurotransmitter-related genes and sexually dimorphic motor deficits in mice
Lozoya, O. A.; Xu, F.; Grenet, D.; Wang, T.; Stevanovic, K.; Cushman, J. D.; Jensen, P.; Hernandez, B.; Riadi, G.; Moy, S.; Santos, J.; Woychik, R.
10.1101/2020.09.18.300418 — neuroscience — Posted on 2020-09-18
1703 Contrasting recruitment of skin-associated adipose depots during cold challenge of mouse and human
Kasza, I.; Kuehn, J.-P.; Volzke, H.; Hernando, D.; Xu, Y. G.; Siebert, J. W.; Gibson, A. L.; Yen, C.-L. E.; Nelson, D. W.; MacDougald, O. A.; Richardson, N. E.; Lamming, D.; Kern, P. A.; Alexander, C.
10.1101/2020.09.16.300533 — physiology — Posted on 2020-09-18
1705 HieRFIT: Hierarchical Random Forest for Information Transfer
Kaymaz, Y.; Ganglberger, F.; Tang, M.; Fernandez-Albert, F.; Lawless, N.; Sackton, T. B.
10.1101/2020.09.16.300822 — bioinformatics — Posted on 2020-09-18
1706 Stoichiometric Modelling of String Chemistries
Moyer, D. C.; Pacheco, A. R.; Bernstein, D. B.; Segre, D.
10.1101/2020.09.16.300491 — bioinformatics — Posted on 2020-09-18
1708 PEA polymer-coated nanotopography delivers solid-state BMP2, enhances mesenchymal stem cell adhesion, prevents bacterial biofilm formation and protects cells from quorum sensing virulence factors
Damiati, L.; Tsimbouri, M.; Ginty, M.; Llopis-Hernandez, V.; Childs, P.; Jayawarna, V.; Xiao, Y.; Burgess, K.; Wells, J.; Sprott, M.; Meek, D.; Li, P.; Oreffo, R.; Nobbs, A.; Ramage, G.; Su, B.; Salmeron-Sanchez, M.; Dalby, M.
10.1101/2020.09.17.302455 — bioengineering — Posted on 2020-09-18
1709 beta-blocker reverses inhibition of beta-2 adrenergic receptor resensitization by hypoxia
Sun, Y.; Gupta, M. K.; Stenson, K.; Mohan, M. L.; Wanner, N.; Asosinght, K.; Erzurum, S.; Naga Prasad, S. N.
10.1101/2020.09.17.301903 — biochemistry — Posted on 2020-09-18
1712 A dual-reporter system for investigating and optimizing protein translation and folding in E. coli
Zutz, A.; Hamborg, L.; Pedersen, L. E.; Kassem, M. M.; Papaleo, E.; Koza, A.; Herrgard, M. J.; Teilum, K.; Lindorff-Larsen, K.; Nielsen, A. T.
10.1101/2020.09.18.303453 — biochemistry — Posted on 2020-09-18
1714 Hybridization capture and low-coverage SNP profiling for extended kinship analysis and forensic identification of historical remains
Gorden, E. M.; Greytak, E. M.; Sturk-Andreaggi, K.; Cady, J.; McMahon, T. P.; Armentrout, S.; Marshall, C.
10.1101/2020.09.17.300715 — genomics — Posted on 2020-09-18
1715 Deep conservation of ribosome stall sites across RNA processing genes
Chyzynska, K.; Labun, K.; Jones, C.; Grellscheid, S. N.; Valen, E.
10.1101/2020.09.17.301754 — genomics — Posted on 2020-09-18
1716 Genetic models suggest single and multiple origins of dihydrofolate reductase mutations in Plasmodium vivax
Shaukat, A.; Ali, Q.; Raud, L.; Wahab, A.; Khan, T. A.; Rashid, I.; Rashid, M.; Hussain, M.; Saleem, M. A.; Sargison, N.; Chaudhry, U.
10.1101/2020.09.18.303586 — genetics — Posted on 2020-09-18
1719 DNA Methylation Reprogramming during Sex Determination and Transition in Zebrafish
Liu, J.; Wang, x.; Ma, x.; Wei, g.; Ma, W.; Zhang, z.; Chen, x.; Gao, L.; Liu, z.; Yuan, y.; Yi, l.; Wang, J.; Tokumoto, T.; Huang, J.; Chen, d.; Zhang, j.
10.1101/2020.09.17.301580 — developmental biology — Posted on 2020-09-18
1720 Unexpected redundancy of Gpr56 and Gpr97 during hematopoietic cell development and differentiation
Maglitto, A.; Mariani, S.; de Pater, E. M.; Rodriguez-Seoane, C.; Vink, C.; Piao, X.; Lukke, M.-L.; Dzierzak, E.
10.1101/2020.09.18.303230 — developmental biology — Posted on 2020-09-18
1721 The P2X7 receptor localizes to the mitochondria, modulates mitochondrial energy metabolism and enhances physical performance
Sarti, A. C.; Vultaggio-Poma, V.; Falzoni, S.; Missiroli, S.; Giuliani, A. L.; Boldrini, P.; Bonora, M.; Faita, F.; Di Lascio, N.; Kusmic, C.; Solini, A.; Novello, S.; Morari, M.; Rossato, M.; Wieckowski, M. R.; Giorgi, C.; Pinton, P.; Di Virgilio, F.
10.1101/2020.09.18.303511 — cell biology — Posted on 2020-09-18
1722 The quorum sensing peptide EntF* promotes colorectal cancer metastasis in mice: a new factor in the microbiome-host interaction.
Debunne, N.; Wynendaele, E.; Janssens, Y.; De Spiegeleer, A.; Verbeke, F.; Tack, L.; Van Welden, S.; Goossens, E.; Knappe, D.; Hoffmann, R.; Van De Wiele, C.; Laukens, D.; Van Eenoo, P.; Van Immerseel, F.; De Wever, O.; De Spiegeleer, B.
10.1101/2020.09.17.301044 — molecular biology — Posted on 2020-09-18
1724 Remarkable recent changes in genetic diversity of the avirulence gene AvrStb6 in global populations of the wheat pathogen Zymoseptoria tritici
Stephens, C.; Olmez, F.; Blyth, H.; McDonald, M.; Bansal, A.; Turgay, E. B.; Hahn, F.; Saintenac, C.; Nekrasov, V.; Solomon, P.; Milgate, A.; Fraaije, B.; Rudd, J. J.; Kanyuka, K.
10.1101/2020.09.18.303370 — microbiology — Posted on 2020-09-18
1725 Piperacillin/tazobactam resistant, cephalosporin susceptible Escherichia coli bloodstream infections driven by multiple resistance mechanisms across diverse sequence types
Edwards, T.; Heinz, E.; van Aartsen, J.; Howard, A.; Roberts, P.; Corless, C.; Fraser, A. J.; Williams, C. T.; Bulgasim, I.; Cuevas, L. E.; Parry, C. M.; Roberts, A. P.; Adams, E. R.; Mason, J.; Hubbard, A.
10.1101/2020.09.18.302992 — microbiology — Posted on 2020-09-18
1727 Single-cell immune landscape of human recurrent spontaneous abortion
Wang, F.; Jia, W.; Fan, M.; Li, Z.; Liu, Y.; Ma, Y.; Shao, X.; Li, Y.; Li, R.; Tu, Q.; Wang, Y.-l.
10.1101/2020.09.16.300939 — immunology — Posted on 2020-09-18
1730 High-sensitivity vision restoration via ectopic expression of chimeric rhodopsin in mice
Katada, Y.; Yoshida, K.; Kobayashi, K.; Hideyuki, O.; Kandori, H.; Tsubota, K.; Kurihara, T.
10.1101/2020.09.17.301523 — neuroscience — Posted on 2020-09-18
1731 Conserved Arginine Residues in Synaptotagmin 1 Regulate Fusion Pore Expansion Through Membrane Contact
Nyenhuis, S. B.; Karandikar, N.; Kiessling, V.; Kreutzberger, A.; Thapa, A.; Liang, B.; Tamm, L. K.; Cafiso, D. S.
10.1101/2020.09.17.301820 — neuroscience — Posted on 2020-09-18
1732 The IgG3 Subclass of β1-adrenergic receptor autoantibody is an endogenous biaser of β1AR signaling
Mohan, M. L.; Nagatomo, Y.; Mukherjee, S.; Engelman, T.; Morales, R.; Tang, W. H. W.; Naga Prasad, S. V.
10.1101/2020.09.17.302059 — pharmacology and toxicology — Posted on 2020-09-18
1736 Evolution of the Analytical Scattering Model of Live Escherichia Coli
Semeraro, E. F.; Marx, L.; Mandl, J.; Frewein, M.; Scott, H.; Prevost, S.; Bergler, H.; Lohner, K.; Pabst, G.
10.1101/2020.09.18.303305 — biophysics — Posted on 2020-09-18
1738 Regulation of protein abundance in genetically diverse mouse populations
Keele, G. R.; Zhang, T.; Pham, D. T.; Vincent, M.; Bell, T. A.; Hock, P.; Shaw, G. D.; Munger, S. C.; de Villena, F. P.-M.; Ferris, M. T.; Gygi, S. P.; Churchill, G. A.
10.1101/2020.09.18.296657 — genomics — Posted on 2020-09-18
1742 Data-driven multiplexed microtomography of endogenous subcellular dynamics
Jo, Y.; Cho, H.; Park, W. S.; Kim, G.; Ryu, D.; Kim, Y. S.; Lee, M.; Joo, H.; Jo, H.; Lee, S.; Min, H.-s.; Heo, W. D.; Park, Y.
10.1101/2020.09.16.300392 — bioengineering — Posted on 2020-09-18
1745 Sexually dimorphic influence of the circadian clock gene Bmal1 in the striatum on alcohol intake
de Zavalia, N.; Schottner, K.; Goldsmith, J. A.; Solis, P.; Ferraro, S.; Parent, G.; Amir, S.
10.1101/2020.09.16.299842 — neuroscience — Posted on 2020-09-18
1746 Subcortical Atlas of the Rhesus Macaque (SARM) for Magnetic Resonance Imaging
Hartig, R.; Glen, D.; Jung, B.; Logothetis, N. K.; Paxinos, G.; Garza-Villarreal, E. A.; Messinger, A.; Evrard, H. C.
10.1101/2020.09.16.300053 — neuroscience — Posted on 2020-09-18
1747 A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent in vitro
Xiao, T.; Lu, J.; Zhang, J.; Johnson, R. I.; McKay, L. G. A.; Storm, N.; Lavine, C. L.; Peng, H.; Cai, Y.; Rits-Volloch, S.; Lu, S.; Quinlan, B. D.; Farzan, M.; Seaman, M. S.; Griffiths, A.; Chen, B.
10.1101/2020.09.18.301952 — microbiology — Posted on 2020-09-18
1748 Discovery of SARS-CoV-2 antiviral synergy between remdesivir and approved drugs in human lung cells
Nguyenla, X.; Wehri, E.; Van Dis, E.; Biering, S.; Yamashiro, L. H.; Stroumza, J.; Dugast-Darzacq, C.; Graham, T.; Stanley, S.; Schaletzky, J.
10.1101/2020.09.18.302398 — microbiology — Posted on 2020-09-18
1749 The COVID-19 immune landscape is dynamically and reversibly correlated with disease severity
Bolouri, H.; Speake, C.; Skibinski, D.; Long, S. A.; Hocking, A. M.; Campbell, D. J.; Hamerman, J. A.; Malhotra, U.; Buckner, J. H.; BRI COVID-19 Research Team,
10.1101/2020.09.18.303420 — immunology — Posted on 2020-09-18
1750 APC mutant cells exploit compensatory chromosome alterations to restore tumour cell fitness
Kawasaki, Y.; Hamaji, T.; Owada, K.; Hayashi, A.; Wu, Y.; Nogi, T.; Okada, M.; Kouyama, Y.; Niida, A.; Mimori, K.; Kuroda, T.; Senda, T.; Ohsugi, M.; Fumoto, K.; Kikuchi, A.; Widlund, P. O.; Kiyosue, K.; Yamashita, N.; Morita, M.; Yokota, H.; Arjunan, S. N. V.; Chew, W.-X.; Takahashi, K.; Legant, W. R.; Chen, B.-C.; Betzig, E.; Smits, R.; Fodde, R.; Oshima, H.; Oshima, M.; Taketo, M. M.; Akiyama, T.; Mimori-Kiyosue, Y.
10.1101/2020.09.18.303016 — cell biology — Posted on 2020-09-18
1752 ESCargo: a regulatable fluorescent secretory cargo for diverse model organisms
Casler, J. C.; Zajac, A. L.; Valbuena, F. M.; Sparvoli, D.; Jeyifous, O.; Turkewitz, A. P.; Horne-Badovinac, S.; Green, W. N.; Glick, B. S.
10.1101/2020.09.17.302133 — cell biology — Posted on 2020-09-18
1754 Release of insulin granules by simultaneous, high-speed correlative SICM-FCM
Bednarska, J.; Novak, P.; Korchev, Y.; Rorsman, P.; Tarasov, A.; Shevchuk, A.
10.1101/2020.09.17.302372 — cell biology — Posted on 2020-09-18
1755 Eicosanoid content in fetal calf serum accounts for reproducibility challenges in cell culture
Niederstaetter, L.; Neuditschko, B.; Brunmair, J.; Janker, L.; Bileck, A.; Del Favero, G.; Gerner, C.
10.1101/2020.09.18.303313 — cell biology — Posted on 2020-09-18
1758 USP28 and SPINT2 mediate cell cycle arrest after whole genome doubling
Storchova, Z.; Seget-Trzensiok, K.; Bernhard, S. V.; Kuffer, C.; Krastev, D. B.; Theiss, M.; Keuper, K.; Boekenkamp, J.-E.; Kschischo, M.; Buchholz, F.
10.1101/2020.09.18.303834 — cell biology — Posted on 2020-09-18
1759 15-PGDH Inhibition Activates the Splenic Niche to Promote Hematopoietic Regeneration
Smith, J. N. P.; Dawson, D. M.; Christo, K. F.; Jogasuria, A. P.; Cameron, M. J.; Antczak, M. I.; Ready, J. M.; Gerson, S. L.; Markowitz, S. D.; Desai, A. B.
10.1101/2020.09.17.302422 — cell biology — Posted on 2020-09-18
1761 Loss of CIB2 causes non-canonical autophagy deficits and visual impairment
Sethna, S. S.; Scott, P. A.; Giese, A. P. J.; Duncan, T.; Redmond, T. M.; Riazuddin, S.; Ahmed, Z. M.
10.1101/2020.09.18.302174 — cell biology — Posted on 2020-09-18
1762 Cortical actin properties controlled by Drosophila Fos aid macrophage infiltration against surrounding tissue resistance
Belyaeva, V.; Wachner, S.; Gridchyn, I.; Linder, M.; Emtenani, S.; Gyoergy, A.; Sibilia, M.; Siekhaus, D.
10.1101/2020.09.18.301481 — cell biology — Posted on 2020-09-18
1764 Heparan sulfate assists SARS-CoV-2 in cell entry and can be targeted by approved drugs in vitro
Zhang, Q.; Chen, C.; Swaroop, M.; Xu, M.; Wang, L.; Lee, J.; Pradhan, M.; Shen, M.; Luo, Z.; Xu, Y.; Huang, W.; Zheng, W.; Ye, Y.
10.1101/2020.07.14.202549 — cell biology — Posted on 2020-09-18
1765 Development of RNA-based assay for rapid detection of SARS-CoV-2 in clinical samples
Kumar, V.; Mishra, S.; Sharma, R.; Agarwal, J.; Ghoshal, U.; Khanna, T.; Sharma, L. K.; Verma, S. K.; Tiwari, S.; Mishra, P.
10.1101/2020.06.30.172833 — microbiology — Posted on 2020-09-18
1766 Preprinting the COVID-19 pandemic
Fraser, N.; Brierley, L.; Dey, G.; Polka, J. K.; Palfy, M.; Nanni, F.; Coates, J. A.
10.1101/2020.05.22.111294 — scientific communication and education — Posted on 2020-09-18
1767 MicroRNA775 Promotes Intrinsic Leaf Size and Reduces Cell Wall Pectin Level via a Target Galactosyltransferase in Arabidopsis
Li, L.; Zhang, H.; Zhuang, Y.; Guo, Z.; Suo, Y.; Du, J.; Gao, Z.; Pan, J.; Li, L.; Wang, T.; Xiao, L.; Qin, G.; Jiao, Y.; Cai, H.
10.1101/2020.09.17.301705 — plant biology — Posted on 2020-09-18
1768 Potential impact on coagulopathy of gene variants of coagulation related proteins that interact with SARS-CoV-2
Holcomb, D.; Alexaki, A.; Hernandez, N.; Laurie, K.; Kames, J.; Hamasaki-Katagiri, N.; Komar, A. A.; DiCuccio, M.; Kimchi-Sarfaty, C.
10.1101/2020.09.08.272328 — bioinformatics — Posted on 2020-09-18
1769 Effect of β-chitosan on the binding interaction between SARS-CoV-2 S-RBD and ACE2
Alitongbieke, G.; Li, X.-M.; Wu, Q.-C.; Lin, Z.-C.; Huang, J.-F.; Xue, Y.; Liu, J.-N.; Lin, J.-M.; Pan, T.; Chen, Y.-X.; Su, Y.; Zhang, G.-G.; Leng, B.; Liu, S.-W.; Pan, Y.-T.
10.1101/2020.07.31.229781 — biochemistry — Posted on 2020-09-18
1770 Histone acetylation at the sulfotransferase 1a1 gene is associated with its hepatic expression in normal aging
Kronfol, M. M.; Dozmorov, M. G.; Jahr, F. M.; Halquist, M. S.; McRae, M.; Wijesinghe, D. S.; Price, E. T.; Slattum, P. W.; McClay, J. L.
10.1101/2020.09.17.300657 — genetics — Posted on 2020-09-18
1771 A Volatile Signal Controls Virulence in the Plant Pathogen Pseudomonas syringae pv. syringae and a Strategy for Infection Control in Organic Farming
Sieber, S.; Mathew, A.; Jenul, C.; Kohler, T.; Bär, M.; Carrion, V. J.; Cazorla, F. M.; Stalder, U.; Hsieh, Y.-C.; Bigler, L.; Eberl, L.; Gademann, K.
10.1101/2020.09.18.279364 — microbiology — Posted on 2020-09-18
1773 A Novel DNA Chromatography Method to Distinguish M. abscessus Subspecies and Macrolide Susceptibility
Yoshida, M.; Sano, S.; Chien, J.-Y.; Fukano, H.; Suzuki, M.; Asakura, T.; Morimoto, K.; Murase, Y.; Miyamoto, S.; Kurashima, A.; Hasegawa, N.; Hsueh, P.-R.; Mitarai, S.; Ato, M.; Hoshino, Y.
10.1101/2020.09.17.292417 — microbiology — Posted on 2020-09-18
1774 Cardiac glycosides cause selective cytotoxicity in human macrophages and ameliorate white adipose tissue homeostasis
Olona, A.; Hateley, C.; Guerrero, A.; Ko, J.-H.; Johnson, M.; Thomas, D.; Gil, J.; Behmoaras, J. R.
10.1101/2020.09.18.293415 — immunology — Posted on 2020-09-18
1775 Transcriptional and morpho-physiological responses of Marchantia polymorpha upon phosphate starvation
Rico-Resendiz, F.; Cervantez-Perez, S. A.; Espinal-Centeno, A.; Dipp-Alvarez, M.; Oropeza-Aburto, A.; Hurtado-Bautista, E.; Cruz-Hernandez, A.; bowman, J. L.; Ishizaki, K.; Arteaga-Vazquez, M.; Herrera-Estrella, L.; Cruz Ramirez, A.
10.1101/2020.09.16.300814 — plant biology — Posted on 2020-09-18
1776 Metabolomic Selection for Enhanced Fruit Flavor
Colantonio, V.; Ferrao, L. F. V.; Tieman, D.; Bliznyuk, N.; Sims, C.; Klee, H.; Munoz, P. R.; Resende, M. F.
10.1101/2020.09.17.302802 — plant biology — Posted on 2020-09-18
1777 TIP family aquaporins play role in chloroplast osmoregulation and photosynthesis
Beebo, A.; Zia, A.; Kinzel, C. R.; Herdean, A.; Bouhidel, K.; Kirchhoff, H.; Schoefs, B.; Spetea, C.
10.1101/2020.09.18.297978 — plant biology — Posted on 2020-09-18
1778 HGNChelper: Identification and correction of invalid gene symbols for human and mouse
Oh, S.; Abdelnabi, J.; Al-Dulaimi, R.; Davis, S. R.; Riester, M.; Waldron, L. D.
10.1101/2020.09.16.300632 — bioinformatics — Posted on 2020-09-18
1779 RatsPub: a webservice aided by deep learning to mine PubMed for addiction-related genes
Gunturkun, M. H.; Flashner, E.; Wang, T.; Mulligan, M. K.; Williams, R. W.; Prins, P.; Chen, H.
10.1101/2020.09.17.297358 — bioinformatics — Posted on 2020-09-18
1780 MiMSI - a deep multiple instance learning framework improves microsatellite instability detection from tumor next-generation sequencing
Ziegler, J.; Hechtman, J. F.; Ptashkin, R.; Jayakumaran, G.; Middha, S.; Chavan, S. S.; Vanderbilt, C.; DeLair, D.; Casanova, J.; Shia, J.; DeGroat, N.; Benayed, R.; Ladanyi, M.; Berger, M. F.; Fuchs, T. J.; Zehir, A.
10.1101/2020.09.16.299925 — bioinformatics — Posted on 2020-09-18
1781 Insight into glycosphingolipid crypticity: Crystal structure of the anti-tumor antibody 14F7 and recognition of NeuGc GM3 ganglioside
Bjerregaard-Andersen, K.; Johannesen, H.; Abraha, F.; Sakanovic, A.; Grosser, D.; Coskun, U.; Anderluh, G.; Oscarson, S.; Moreno, E.; Grzybek, M.; Krengel, U.
10.1101/2020.09.18.294777 — biochemistry — Posted on 2020-09-18
1783 Inference of recent admixture using genotype data
Pfaffelhuber, P.; Sester-Huss, E.; Baumdicker, F.; Naue, J.; Lutz-Bonengel, S.; Staubach, F.
10.1101/2020.09.16.300640 — genetics — Posted on 2020-09-18
1785 Function of the HYDROXYCINNAMOYL-CoA:SHIKIMATE HYDROXYCINNAMOYL TRANSFERASE is evolutionarily conserved in embryophytes
Kriegshauser, L.; Knosp, S.; Grienenberger, E.; Gütle, D. D.; Sorensen, I.; Herrgott, L.; Zumsteg, J.; Rose, J. K. C.; Reski, R.; Werck, D.; Renault, H.
10.1101/2020.09.16.300285 — plant biology — Posted on 2020-09-18
1788 Relating neural oscillations to laminar fMRI connectivity
Scheeringa, R.; Bonnefond, M.; van Mourik, T.; Jensen, O.; Norris, D. G.; Koopmans, P. J.
10.1101/2020.09.18.303263 — neuroscience — Posted on 2020-09-18
1791 Bacterial single-cell genomics enables phylogenetic analysis and reveals population structures from in vitro evolutionary studies
Bawn, M.; Hernandez, J.; Trampari, E.; Thilliez, G.; Webber, M. A.; Kingsley, R. A.; Hall, N.; Macaulay, I. C.
10.1101/2020.08.25.266213 — genomics — Posted on 2020-09-18
1793 ImmunoCluster: A computational framework for the non-specialist to profile cellular heterogeneity in cytometry datasets
Opzoomer, J. W.; Timms, J. A.; Blighe, K.; Mourikis, T. P.; Chapuis, N.; Bekoe, R.; Kareemaghay, S.; Nocerino, P.; Apollonio, B.; Ramsay, A. G.; Tavassoli, M.; Harrison, C.; Ciccarelli, F.; Parker, P.; Fontenay, M.; Barber, P.; Arnold, J. N.; Kordasti, S.
10.1101/2020.09.09.289033 — systems biology — Posted on 2020-09-18
1794 Personalized Cancer Therapy Prioritization Based on Driver Alteration Co-occurrence Patterns
Mateo, L.; Duran-Frigola, M.; Gris-Oliver, A.; Palafox, M.; Scaltriti, M.; Razavi, P.; Chandarlapaty, S.; Arribas, J.; Bellet, M.; Serra, V.; Aloy, P.
10.1101/772673 — cancer biology — Posted on 2020-09-18
1797 Bioactivity descriptors for uncharacterized compounds
Bertoni, M.; Duran-Frigola, M.; Badia-i-Mompel, P.; Pauls, E.; Orozco-Ruiz, M.; Guitart-Pla, O.; Alcalde, V.; Diaz, V. M.; Berenguer-Llergo, A.; Garcia de Herreros, A.; Aloy, P.
10.1101/2020.07.21.214197 — bioinformatics — Posted on 2020-09-18
1799 Climate explains geographic and temporal variation in mosquito-borne disease dynamics on two continents
Caldwell, J. M.; LaBeaud, A. D.; Lambin, E. F.; Stewart-Ibarra, A. M.; Ndenga, B. A.; Mutuku, F. M.; Krystosik, A. R.; Ayala, E. B.; Anyamba, A.; Borbor-Cordova, M. J.; Damoah, R.; Grossi-Soyster, E. N.; Heras Heras, F.; Ngugi, H. N.; Ryan, S. J.; Shah, M. M.; Sippy, R.; Mordecai, E. A.
10.1101/2020.02.07.938720 — ecology — Posted on 2020-09-18
1803 Structural basis of client specificity in mitochondrial membrane-protein chaperones
Sucec, I.; Wang, Y.; Dakhlaoui, O.; Weinhäupl, K.; Jores, T.; Costa, D.; Hessel, A.; Brennich, M.; Rapaport, D.; Lindorff-Larsen, K.; Bersch, B.; Schanda, P.
10.1101/2020.06.08.140772 — biophysics — Posted on 2020-09-17
1805 Struct2Graph: A graph attention network for structure based predictions of protein-protein interactions
Baranwal, M.; Magner, A.; Saldinger, J.; Turali-Emre, E. S.; Kozarekar, S.; Elvati, P.; VanEpps, J. S.; Kotov, N.; Violi, A.; Hero, A. O.
10.1101/2020.09.17.301200 — bioinformatics — Posted on 2020-09-17
1806 Geographic heterogeneity impacts drug resistance predictions in Mycobacterium tuberculosis
Gan, G. L.; Nguyen, M.; Willie, E.; Lee, B.; Chauve, C.; Libbrecht, M.; Chindelevitch, L.
10.1101/2020.09.17.301226 — bioinformatics — Posted on 2020-09-17
1807 Emergence and expansion of highly infectious spike:D614G mutant SARS-CoV-2 in central India
Sharma, S.; Dash, P. K.; Sharma, S. K.; Srivastava, A.; Kumar, J. S.; Karothia, B. S.; Chelvam, K. T.; Singh, S.; Gupta, A.; Yadav, R. G.; Yadav, R.; S, G. T.; Kushwah, P.; Bhushan, R.; Nagar, D. P.; Nandan, M.; Kumar, S.; Thavaselvam, D.; Dubey, D. K.
10.1101/2020.09.15.297846 — molecular biology — Posted on 2020-09-17
1808 Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) is a druggable target involved in parasite survival, oviposition and stem cell proliferation.
Padalino, G.; Celatka, C. A.; Rienhoff, H. Y.; Kalin, J. H.; Cole, P. A.; Lassalle, D.; Grunau, C.; Chalmers, I. W.; Brancale, A.; Hoffmann, K. F.
10.1101/2020.09.17.301184 — microbiology — Posted on 2020-09-17
1812 GmSALT3 confers shoot Na+ and Cl- exclusion in soybean via two distinct processes.
Qu, Y.; Guan, R.; Bose, J.; Henderson, S. W.; Wege, S.; Qiu, L.-J.; Gilliham, M.
10.1101/2020.01.06.896456 — plant biology — Posted on 2020-09-17
1814 IL-6 Trans-Signaling and Tumor-Muscle-Adipose Crosstalk Mediate Pancreatic Cancer Cachexia
Rupert, J. E.; Bonetto, A.; Narasimhan, A.; Liu, Y.; O'Connell, T. M.; Koniaris, L. G.; Zimmers, T.
10.1101/2020.09.16.300798 — cancer biology — Posted on 2020-09-17
1818 Candidatus (Ca.) phytoplasma asteris subgroups display distinct disease progression dynamics during the carrot growing season
Clements, J.; Bradford, B. Z.; Garcia, M.; Piper, S.; Huang, W.; Zwolinska, A.; Lamour, K.; Hogenhout, S.; Groves, R. L.
10.1101/2020.09.17.301150 — ecology — Posted on 2020-09-17
1820 Role of Mcpip1 in obesity-induced hepatic steatosis as determined by myeloid and liver-specific conditional knockouts.
Pydyn, N.; Zurawek, D.; Koziel, J.; Kus, E.; Wojnar-Lason, K.; Jasztal, A.; Fu, M.; Jura, J.; Kotlinowski, J.
10.1101/2020.09.17.301531 — molecular biology — Posted on 2020-09-17
1821 CRISPRi screens reveal genes modulating yeast growth in lignocellulose hydrolysate
Gutmann, F.; Jann, C.; Pereira, F.; Johansson, A.; Steinmetz, L. M.; Patil, K. R.
10.1101/2020.09.17.301416 — microbiology — Posted on 2020-09-17
1822 Microbiome-related aspects of locust density-dependent phase transition
Lavy, O.; Lewin-Epstein, O.; Bendett, Y.; Gophna, U.; Gefen, E.; Hadany, L.; Ayali, A.
10.1101/2020.09.17.301010 — microbiology — Posted on 2020-09-17
1827 The organization and developmental establishment ofcortical interneuron presynaptic circuits
Pouchelon, G.; Bollmann, Y.; Fisher, E.; Agba, C. K.; Xu, Q.; Ritola, K. D.; Mirow, A. M.; Kim, S.; Cossart, R.; Fishell, G.
10.1101/2020.09.17.302117 — neuroscience — Posted on 2020-09-17
1831 Schlafen family member 5 (SLFN5) regulates LAT1-mediated mTOR activation in castration-resistant prostate cancer
Martinez, R. S.; Salji, M. J.; Rushworth, L.; Ntala, C.; Rodriguez Blanco, G.; Hedley, A.; Clark, W.; Peixoto, P.; Hervouet, E.; Renaude, E.; Kung, S. H.; Galbraith, L. C.; Nixon, C.; Lilla, S.; MacKay, G. M.; Fazli, L.; Sumpton, D.; Gleave, M. E.; Zanivan, S. R.; Blomme, A.; Leung, H. Y.
10.1101/2020.09.17.301283 — cancer biology — Posted on 2020-09-17
1833 THE IMPACT OF THE HYDROXYMETHYLCYTOSINE EPIGENETIC SIGNATURE ON DNA STRUCTURE AND FUNCTION
Battistini, F.; Dans, P.; Terrazas, M.; Castellazzi, C. L.; Portella, G.; Labrador, M.; Villegas, N.; Brun-Heath, I.; Gonzalez, C.; Orozco, M.
10.1101/2020.09.17.285452 — biochemistry — Posted on 2020-09-17
1834 Myeloid cell-associated resistance to PD-1/PD-L1 blockade in urothelial cancer revealed through bulk and single-cell RNA sequencing
Wang, L.; Sfakianos, J. P.; Beaumont, K. G.; Akturk, G.; Horowitz, A.; Sebra, R.; Farkas, A. M.; Gnjatic, S.; Hake, A.; Izadmehr, S.; Wiklund, P.; Oh, W. K.; Szabo, P.; Wind-Rotolo, M.; Unsal-Kacmaz, K.; Yao, X.; Schadt, E.; Sharma, P.; Bhardwaj, N.; Zhu, J.; Galsky, M. D.
10.1101/2020.09.16.300111 — genomics — Posted on 2020-09-17
1836 Common variants contribute to intrinsic human brain functional networks
Zhao, B.; Li, T.; Smith, S. M.; Xiong, D.; Wang, X.; Yang, Y.; Luo, T.; Zhu, Z.; Shan, Y.; Matoba, N.; Sun, Q.; Yang, Y.; Hauberg, M. E.; Bendl, J.; Fullard, J. F.; Roussos, P.; Lin, W.; Li, Y.; Stein, J. L.; Zhu, H.
10.1101/2020.07.30.229914 — genetics — Posted on 2020-09-17
1838 Contrasting tempos of sex chromosome degeneration in sticklebacks
Sardell, J. M.; Josephson, M. P.; Dalziel, A. C.; Peichel, C. L.; Kirkpatrick, M.
10.1101/2020.09.17.300236 — evolutionary biology — Posted on 2020-09-17
1840 PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates
Xu, Y.-f.; Sun, J.; Yu, X.; Chen, X.; Cui, M.; Yang, Z.; Liu, C.-h.; Yang, X.-z.; Wang, Y.-j.; Zhang, S.; Wang, C.; Zhang, Z.-y.; Zhao, W.-d.; Wang, C.-h.; Ji, Z.-l.; Xiao, P.; Li, K.-s.; Xu, Z.-G.; Zhu, Z.-L.; Song, Y.-c.
10.1101/822031 — cell biology — Posted on 2020-09-17
1843 Expression of ERV3-1 in Leukocytes of Acute Myelogenous Leukemia Patients
Nakagawa, S.; Kawashima, M.; Miyatake, Y.; Kudo, K.; Kotaki, R.; Ando, K.; Kotani, A.
10.1101/2020.09.16.300905 — molecular biology — Posted on 2020-09-17
1844 Topoisomerase II deficiency leads to a postreplicative structural shift in all Saccharomyces cerevisiae chromosomes.
Ayra-Plasencia, J.; Ramos-Perez, C.; Santana-Sosa, S.; Quevedo, O.; Medina-Suarez, S.; Matos-Perdomo, E.; Zamora-Dorta, M.; Brown, G. W.; Lisby, M.; Machin, F.
10.1101/2020.09.17.301317 — molecular biology — Posted on 2020-09-17
1852 Relative matching using low coverage sequencing
Petter, E.; Schweiger, R.; Shahino, B.; Shor, T.; Aker, M.; Almog, L.; Weissglas-Volkov, D.; Naveh, Y.; Navon, O.; Carmi, S.; Li, J. H.; Berisa, T.; Pickrell, J. K.; Erlich, Y.
10.1101/2020.09.09.289322 — bioinformatics — Posted on 2020-09-17
1859 The island rule explains consistent patterns of body size evolution across terrestrial vertebrates
Benitez-Lopez, A.; Santini, L.; Gallego-Zamorano, J.; Mila, B.; Walkden, P.; Huijbregts, M. A. J.; Tobias, J. A.
10.1101/2020.05.25.114835 — ecology — Posted on 2020-09-17
1865 Genome-Wide Association Mapping of Sugarcane Yellow Leaf Virus Resistance
Pimenta, R. J. G.; Aono, A. H.; Villavicencio, R. C. B.; da Silva, C. C.; dos Anjos, I. A.; Landell, M. G. d. A.; Gonçalves, M. C.; Pinto, L. R.; de Souza, A. P.
10.1101/2020.09.04.283614 — plant biology — Posted on 2020-09-17
1866 Lignin-based resistance to Cuscuta campestris parasitism in Heinz resistant tomato cultivars
Jhu, M.-Y.; Farhi, M.; Wang, L.; Philbrook, R. N.; Belcher, M. S.; Nakayama, H.; Zumstein, K. S.; Rowland, S. D.; Ron, M.; Shih, P. M.; Sinha, N. R.
10.1101/706861 — plant biology — Posted on 2020-09-17
1868 Sex and Power: sexual dimorphism in trait variability and its eco-evolutionary and statistical implications
Zajitschek, S. R. K.; Zajitschek, F.; Bonduriansky, R.; Brooks, R. C.; Cornwell, W. K.; Falster, D. S.; Lagisz, M.; Mason, J.; Senior, A.; Noble, D.; Nakagawa, S.
10.1101/2020.05.23.106146 — evolutionary biology — Posted on 2020-09-17
1869 No Evidence for a Difference in 2D:4D Ratio between Youth with Elevated Prenatal Androgen Exposure due to Congenital Adrenal Hyperplasia and Controls
Nave, G.; Koppin, C. M.; Manfredi, D.; Richards, G.; Watson, S. J.; Geffner, M. E.; Yong, J. E.; Kim, R.; Ross, H. M.; Serrano-Gonzalez, M.; Kim, M. S.
10.1101/2020.05.07.082529 — developmental biology — Posted on 2020-09-17
1870 Alpha-synuclein enhances lipid droplet accumulation in neurons in a Drosophila model of Parkinson's disease
Girard, V.; Jollivet, F.; Knittelfelder, O.; Arsac, J.-N.; Chatelain, G.; Van den Brink, D.; Baron, T.; Shevchenko, A.; Davoust-Nataf, N.; Mollereau, B.
10.1101/2020.09.16.299354 — cell biology — Posted on 2020-09-17
1871 Maladaptive nutrient signalling sustains the m.3243A>G mtDNA mutation
Chung, C.-Y.; Singh, K.; Kotiadis, V. N.; Ahn, J. H.; Kabir, L.; Topley, E.; Tan, J.; Andrews, W. D.; Plotegher, N.; Guella, G.; Pitceathly, R. D. S.; Szabadkai, G.; Yuneva, M.; Duchen, M. R.
10.1101/2020.06.18.159103 — cell biology — Posted on 2020-09-17
1872 Distinct SARS-CoV-2 Antibody Reactivity Patterns in Coronavirus Convalescent Plasma Revealed by a Coronavirus Antigen Microarray
Ramiro de Assis, R.; Jain, A.; Nakajima, R.; Jasinskas, A.; Khan, S.; Dumont, L. J.; Kelly, K.; Simmons, G.; Stone, M.; Di Germanio, C.; Busch, M. P.; Felgner, P. L.
10.1101/2020.09.16.300871 — immunology — Posted on 2020-09-17
1873 Non-canonical roles of caspase-4 and caspase-5 in heme driven- IL-1β release and cell death
Bolivar, B. E.; Brown, A. N.; Rohrman, B. A.; Charendoff, C. I.; Yazdani, V.; Belcher, J. D.; Vercellotti, G. M.; Flanagan, J. M.; Bouchier-Hayes, L.
10.1101/2020.02.28.969899 — immunology — Posted on 2020-09-17
1874 Predictive learning as a network mechanism forextracting low-dimensional latent spacerepresentations
Recanatesi, S.; Farrell, M.; Lajoie, G.; Deneve, S.; Rigotti, M.; Shea-Brown, E.
10.1101/471987 — neuroscience — Posted on 2020-09-17
1876 Calcium imaging and the curse of negativity
Vanwalleghem, G. C.; Constantin, L.; Scott, E. K.
10.1101/2020.09.15.298885 — neuroscience — Posted on 2020-09-17
1879 AutoGenome V2: New Multimodal Approach Developed for Multi-Omics Research
Xu, C.; Liu, D.; Zhang, L.; Xu, Z.; He, W.; Wang, D.; Zheng, M.; Qiao, N.
10.1101/2020.04.02.021345 — bioinformatics — Posted on 2020-09-17
1884 Functional dynamics of de-afferented early visual cortex in glaucoma
Prabhakaran, G. T.; Al-nosairy, K. O.; Tempelmann, C.; Wagner, M.; Thieme, H.; Hoffmann, M. B.
10.1101/2020.09.16.300012 — neuroscience — Posted on 2020-09-17
1885 Evidences for a nutritional role of iodine in plants
Kiferle, C.; Martinelli, M.; Salzano, A. M.; Gonzali, S.; Beltrami, S.; Salvadori, P. A.; Hora, K.; Holwerda, H. T.; Scaloni, A.; Perata, P.
10.1101/2020.09.16.300079 — plant biology — Posted on 2020-09-17
1890 Topographic Guidance in Melt-Electrowritten Tubular Scaffolds Enhances Engineered Kidney Tubule Performance
van Genderen, A. M.; Jansen, K.; Kristen, M.; van Duijn, J.; Li, Y.; Schuurmans, C. C. L.; Malda, J.; Vermonden, T.; Jansen, J.; Masereeuw, R.; Castilho, M.
10.1101/2020.09.16.300004 — bioengineering — Posted on 2020-09-17
1894 Early-life environment programs reproductive strategies through epigenetic regulation of SRD5A1
Bar-Sadeh, B.; Eden, O.; Pnueli, L.; Begum, K.; Leeman, G.; Emes, R. D.; Stoger, R.; Bentley, G. R.; Melamed, P.
10.1101/2020.09.16.299560 — developmental biology — Posted on 2020-09-17
1900 A method to remove the influence of fixative concentration on post-mortem T2 maps using a Kinetic Tensor model
Tendler, B. C.; Qi, F.; Foxley, S.; Pallebage-Gamarallage, M.; Menke, R. A. L.; Ansorge, O.; Hurley, S. A.; Miller, K. L.
10.1101/2020.09.16.299784 — neuroscience — Posted on 2020-09-17
1902 Structural and Functional Comparison of SARS-CoV-2-Spike Receptor Binding Domain Produced in Pichia pastoris and Mammalian Cells
Argentinian AntiCovid Consortium, ; Arbeitman, C. R.; Auge, G.; Blaustein, M.; Bredeston, L.; Corapi, E. S.; Craig, P. O.; Cossio, L. A.; Dain, L.; D'Alessio, C.; Elias, F.; Fernandez, N. B.; Gasulla, J.; Gorojovsky, N.; Gudesblat, G. E.; Herrera, M. G.; Ibanez, L. I.; Idrovo, T.; Iglesias Rando, M.; Kamenetzky, L.; Nadra, A. D.; Noseda, D. G.; Pavan, C. H.; Pavan, M. F.; Pignataro, M. F.; Roman, E.; Ruberto, L. A. M.; Rubinstein, N.; Santos, J.; Velazquez, F.; Zelada, A. M.
10.1101/2020.09.17.300335 — biochemistry — Posted on 2020-09-17
1905 Comparison of Rhesus and Cynomolgus macaques as an authentic model for COVID-19.
Salguero, F. J.; White, A. D.; Slack, G. S.; Fotheringham, S. A.; Bewley, K. R.; Gooch, K. E.; Longet, S.; Humphries, H. E.; Watson, R. J.; Hunter, L.; Ryan, K. A.; Hall, Y.; Sibley, L.; Sarfas, C.; Allen, L.; Aram, M.; Brunt, E.; Brown, P.; Buttigieg, K. R.; Cavell, B. E.; Cobb, R.; Coombes, N. S.; Daykin-Pont, O.; Elmore, M. J.; Gkolfinos, K.; Godwin, K. J.; Gouriet, J.; Halkerston, R.; Harris, D. J.; Hender, T.; Ho, C. M. K.; Kennard, C. L.; Knott, D.; Leung, S.; Lucas, V.; Mabbutt, A.; Morrison, A. L.; Ngabo, D.; Paterson, J.; Penn, E. J.; Pullan, S.; Taylor, I.; Tipton, T.; Thomas, S.; Tr
10.1101/2020.09.17.301093 — microbiology — Posted on 2020-09-17
1906 Identification of novel antiviral drug combinations in vitro and tracking their development
Ianevski, A.; Yao, R.; Biza, S.; Zusinaite, E.; Mannik, A.; Kivi, G.; Planken, A.; Kurg, K.; Tombak, E.-M.; Ustav, M.; Shtaida, N.; Kulesskiy, E.; Jo, E.; Yang, J.; Lysvand, H.; Loseth, K.; Oksenych, V.; Aas, P. A.; Tenson, T.; Vitkauskiene, A.; Windisch, M. P.; Fenstad, M. H.; Nordbo, S. A.; Ustav, M.; Bjoras, M.; Kainov, D. E.
10.1101/2020.09.17.299933 — microbiology — Posted on 2020-09-17
1908 Distinct SARS-CoV-2 Antibody Reactivity Patterns in Coronavirus Convalescent Plasma Revealed by a Coronavirus Antigen Microarray
Ramiro de Assis, R.; Jain, A.; Nakajima, R.; Jasinskas, A.; Khan, S.; Dumont, L. J.; Kelly, K.; Simmons, G.; Stone, M.; Di Germanio, C.; Busch, M. P.; Felgner, P. L.
10.1101/2020.09.16.300871 — immunology — Posted on 2020-09-17
1909 Monocytes and macrophages, targets of SARS-CoV-2: the clue for Covid-19 immunoparalysis
Boumaza, A.; Gay, L.; Mezouar, S.; Diallo, A. B.; Michel, M.; Desnues, B.; Raoult, D.; LA SCOLA, B.; Halfon, P.; Vitte, J.; Olive, D.; Mege, J.-L.
10.1101/2020.09.17.300996 — immunology — Posted on 2020-09-17
1915 Reciprocal connectivity of the periaqueductal gray with the ponto-medullary respiratory network in rat.
Trevizan-Bau, P.; Furuya, W. I.; Mazzone, S. B.; Stanic, D.; Dhingra, R. R.; Dutschmann, M.
10.1101/2020.09.15.298927 — neuroscience — Posted on 2020-09-17
1919 Bio-hybrid soft robots with self-stimulating skeletons
Guix, M.; Mestre, R.; Patino, T.; de Corato, M.; Zarpellon, G.; Sanchez, S.
10.1101/2020.09.16.299719 — bioengineering — Posted on 2020-09-17
1922 Holstein Friesian dairy cattle edited for diluted coat color as adaptation to climate change
Laible, G.; Cole, S.-A.; Brophy, B.; Leath, S.; Jivanji, S.; Littlejohn, M. D.; Wells, D. N.
10.1101/2020.09.15.298950 — genetics — Posted on 2020-09-17
1923 Open Targets Genetics: An open approach to systematically prioritize causal variants and genes at all published GWAS trait-associated loci
Mountjoy, E.; Schmidt, E. M.; Carmona, M.; Peat, G.; Miranda, A.; Fumis, L.; Hayhurst, J.; Buniello, A.; Schwartzentruber, J.; Karim, M. A.; Wright, D.; Hercules, A.; Papa, E.; Fauman, E.; Barrett, J. C.; Todd, J. A.; Ochoa, D.; Dunham, I.; Ghoussaini, M.
10.1101/2020.09.16.299271 — genetics — Posted on 2020-09-17
1924 Selection of lamb size and early pregnancy in Soay sheep (Ovies aries)
Janeiro, M. J.; Henshaw, J. M.; Pemberton, J. M.; Pilkington, J. G.; Morrissey, M. B.
10.1101/2020.09.16.299685 — evolutionary biology — Posted on 2020-09-17
1926 Obesity control by SHIP inhibition requires pan-paralog inhibition and an intact eosinophil compartment
Kerr, W.; Fernandes, S.; Srivastava, N.; Pedicone, C.; Sudan, R.; Luke, E.; Dungan, O.; Pacherille, A.; Meyer, S. T.; Dormann, S.; Chisholm, J. D.
10.1101/2020.09.15.299073 — immunology — Posted on 2020-09-17
1927 Unraveling the Developmental Dynamic of Visual Exploration of Social Interactions in Autism
Kojovic, N.; Franchini, M.; Sandini, C.; Sperdin, H. F.; Jan, R. K.; Zoeller, D.; Schaer, M.
10.1101/2020.09.14.290106 — neuroscience — Posted on 2020-09-17
1928 Conductance-Based Structural Brain Connectivity in Aging and Dementia
Frau-Pascual, A.; Augustinak, J.; Varadarajan, D.; Yendiki, A.; Salat, D. H.; Fischl, B.; Aganj, I.
10.1101/2020.09.15.298331 — neuroscience — Posted on 2020-09-17
1933 A comprehensive benchmarking of WGS-based structural variant callers
Sarwal, V.; Niehus, S.; Ayyala, R.; Chang, S.; Lu, A.; Darci-Maher, N.; Littman, R.; Chhugani, K.; Soylev, A.; Comarova, Z.; Wesel, E.; Castellanos, J.; Chikka, R.; Distler, M. G.; Eskin, E.; Flint, J.; Mangul, S.
10.1101/2020.04.16.045120 — bioinformatics — Posted on 2020-09-17
1934 Alpha-synuclein enhances lipid droplet accumulation in neurons in a Drosophila model of Parkinson's disease
Mollereau, B.; Girard, V.; Jollivet, F.; Knittelfelder, O.; Arsac, J.-N.; Chatelain, G.; Van den Brink, D.; Baron, T.; Shevchenko, A.; Davoust-Nataf, N.
10.1101/2020.09.16.299354 — cell biology — Posted on 2020-09-17
1936 The zinc finger antiviral protein ZAP destabilises viral transcripts and restricts cytomegalovirus
Gonzalez-Perez, A. C.; Stempel, M.; Wyler, E.; Urban, C.; Piras, A.; Hennig, T.; Heim, A.; Landthaler, M.; Pichlmair, A.; Erhard, F.; Dölken, L.; Brinkmann, M. M.
10.1101/2020.09.15.297804 — molecular biology — Posted on 2020-09-17
1939 A clock in mouse cones contributes to the retinal oscillator network and to synchronization of the circadian system
Sandu, C.; Wongchitrat, P.; Mazzaro, N.; Jaeger, C.; Calligaro, H.; Mendoza, J.; Hicks, D.; Felder-Schmittbuhl, M.-P.
10.1101/2020.09.15.297879 — neuroscience — Posted on 2020-09-17
1943 Shared and distinct genetic influences between cognitive domains and psychiatric disorder risk based on genome-wide data
Carey, C. E.; Huang, Y.; Strong, R. W.; 23andMe Research Team, ; Aslibekyan, S.; Gentleman, R. C.; Smoller, J. W.; Wilmer, J. B.; Robinson, E. B.; Germine, L.
10.1101/2020.09.16.297408 — genetics — Posted on 2020-09-17
1947 Refining pairwise sequence alignments of membrane proteins by the incorporation of anchors
Staritzbichler, R.; Sarti, E.; Yaklich, E.; Stamm, M.; Aleksandrova, A.; Khafizov, K.; Forrest, L. R.
10.1101/2020.09.16.299453 — bioinformatics — Posted on 2020-09-16
1948 Efficient Development of Platform Cell Lines Using CRISPR-Cas9 and Transcriptomics Analysis
Kwon, A. T.-J.; Mohri, K.; Takizawa, S.; Arakawa, T.; Takahashi, M.; Kaczkowski, B.; Furuno, M.; Suzuki, H.; Tagami, S.; Mukai, H.; Arner, E.
10.1101/2020.09.16.299248 — bioengineering — Posted on 2020-09-16
1949 Live imaging and biophysical modeling support a button-based mechanism of somatic homolog pairing in Drosophila
Child, M. B.; Bateman, J. R.; Jahangiri, A.; Reimer, A.; Lammers, N. C.; Sabouni, N.; Villamarin, D.; McKenzie-Smith, G. C.; Johnson, J. E.; Jost, D.; Garcia, H. G.
10.1101/2020.08.30.265108 — developmental biology — Posted on 2020-09-16
1950 Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveola formation
Tillu, V.; Rae, J.; Gao, Y.; Ariotti, N.; Floetenmeyer, M.; Kovtun, O.; McMahon, K.-A.; Chaudhary, N.; Parton, R. G.; Collins, B. M.
10.1101/831149 — cell biology — Posted on 2020-09-16
1951 Influence of Activating and Inhibitory Killer Immunoglobulin-Like Receptors (KIR) genes on the recurrence rate of ocular toxoplasmosis in Brazil
Silva, D. S. P.; Joaquim, T. E.; do Couto, A. L. Q.; Motta, J.; Ribeiro-Alves, M.; Ferreira, J. d. O.; de Moraes Sobrino, L. C. P.; Banic, D. M.; Reis Amendoeira, M. R.
10.1101/2020.09.16.299446 — molecular biology — Posted on 2020-09-16
1953 Extracellular DJ-1 induces sterile inflammation in the ischemic brain
Nakamura, K.; Sakai, S.; Tsuyama, J.; Nakamura, A.; Otani, K.; Kurabayashi, K.; Yogiashi, Y.; Masai, H.; Shichita, T.
10.1101/2020.09.16.299420 — immunology — Posted on 2020-09-16
1958 Proteome-wide Profiling of RNA-Binding Protein Responses to flg22 Reveals Novel Components of Plant Immunity
Bach-Pages, M.; Chen, H.; Sanguankiattichai, N.; Soldan, R.; Kaschani, F.; Kaiser, M.; Mohammed, S.; van der Hoorn, R.; Castello, A.; Preston, G.
10.1101/2020.09.16.299701 — molecular biology — Posted on 2020-09-16
1959 Transcriptome analysis of EPO and GFP HEK293 Cell-lines Reveal Shifts in Energy and ER Capacity Support Improved Erythropoietin Production in HEK293F Cells
Saghaleyni, R.; Malm, M.; Zrimec, J.; Razavi, R.; Wistbacka, N.; Chotteau, V.; Hatton, D.; Grassi, L.; Zelezniak, A.; Svensson, T.; Nielsen, J.; Robinson, J. L.; Rockberg, J.
10.1101/2020.09.16.299966 — systems biology — Posted on 2020-09-16
1960 Evaluations of CRC2631 toxicity, tumor colonization, and genetic stability in the TRAMP prostate cancer model
Kazmierczak, R.; Dhagat-Mehta, B.; Gulden, E.; Lee, L.; Ma, L.; Davis-Stober, C. P.; Barnett, A. A.; Chabu, C. Y.
10.1101/2020.09.15.299081 — cancer biology — Posted on 2020-09-16
1961 High-resolution Crystal Structures of Transient Intermediates in the Phytochrome Photocycle
Carrillo, M.; Pandey, S.; Sanchez, J.; Noda, M.; Poudyal, I.; Aldama, L.; Malla, T. N.; Claesson, E.; Yuan Wahlgreen, W.; Feliz, D.; Srajer, V.; Maj, M.; Castillon, L.; Iwata, S.; Nango, E.; Tanaka, R.; Tanaka, T.; Fangjia, L.; Tono, K.; Owada, S.; Westenhoff, S.; Stojkovic, E.; Schmidt, M.
10.1101/2020.09.16.298463 — biophysics — Posted on 2020-09-16
1964 Smad3 Regulates Smooth Muscle Cell Fate and Governs Adverse Remodeling and Calcification of Atherosclerotic Plaque
Cheng, P.; Wirka, r.; Kim, J.; Nguyen, T.; Kundu, R.; Zhao, q.; Pedroza, A.; Nagao, M.; Iyer, D.; Fischbein, M.; Quertermous, T.
10.1101/2020.09.15.299131 — cell biology — Posted on 2020-09-16
1965 BRD4-mediated repression of p53 is a target for combination therapy in AML
Latif, A.-L.; Newcombe, A.; Li, S.; Gilroy, K.; Robertson, N.; Lei, X.; Stewart, H.; Cole, J.; Terradas, M. T.; Rishi, L.; McGarry, L.; McKeeve, C.; Reid, C.; Clark, W.; Campos, J.; Kirschner, K.; Davis, A. E.; Lopez, J.; Sakamaki, J.-I.; Morton, J.; Ryan, K. M.; Tait, S.; Abraham, S.; Holyoake, T.; Higgens, B.; Huang, X.; Blyth, K.; Copland, M.; Chevassut, T.; Keeshan, K.; Adams, P. D.
10.1101/2020.09.16.291930 — cell biology — Posted on 2020-09-16
1968 Influenza A virus-induced thymus atrophy differentially affects dynamics of conventional and regulatory T cell development
Elfaki, Y.; Robert, P. A.; Binz, C.; Falk, C. S.; Bruder, D.; Prinz, I.; Flöss, S.; Meyer-Hermann, M.; Hühn, J.
10.1101/2020.09.09.274795 — immunology — Posted on 2020-09-16
1969 The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling
Zhang, S.; Wang, Y.; Zhu, X.; Song, L.; Ma, E.; McDonough, J.; Fu, H.; Cambi, F.; Grinspan, J.; Guo, F.
10.1101/2020.09.16.300624 — neuroscience — Posted on 2020-09-16
1974 An expanded gene catalog of mouse gut metagenome
Zhu, J.; Ren, H.; Zhong, H.; Li, X.; Zou, Y.; Han, M.; Li, M.; Madsen, L.; Kristiansen, K.; Xiao, L.
10.1101/2020.09.16.299339 — bioinformatics — Posted on 2020-09-16
1976 Efficient Development of Platform Cell Lines Using CRISPR-Cas9 1 and Transcriptomics Analysis
Kwon, A. T.-J.; Mohri, K.; Takizawa, S.; Arakawa, T.; Takahashi, M.; Kaczkowski, B.; Furuno, M.; Suzuki, H.; Tagami, S.; Mukai, H.; Arner, E.
10.1101/2020.09.16.299248 — bioengineering — Posted on 2020-09-16
1978 Inhibition of Streptococcus pneumoniae autolysins highlight distinct differences between chemical and genetic inactivation
Haubrich, B. A.; Nayyab, S.; Williams, C.; Whitman, A.; Zimmerman, T.; Li, Q.; Chen, Y.; Zhou, C.-Z.; Basu, A.; Reid, C. W.
10.1101/2020.09.16.300541 — biochemistry — Posted on 2020-09-16
1979 Targeted Proteomics Reveals Quantitative Differences in Low Abundance Glycosyltransferases of Patients with Congenital Disorders of Glycosylation
Sakson, R.; Beedgen, L.; Bernhard, P.; Alp, K. M.; Luebbehusen, N.; Roeth, R.; Niesler, B.; Mayer, M. P.; Thiel, C.; Ruppert, T.
10.1101/2020.09.15.291732 — biochemistry — Posted on 2020-09-16
1981 X chromosome-dependent disruption of placental regulatory networks in hybrid dwarf hamsters
Brekke, T. D.; Moore, E. C.; Campbell-Staton, S. C.; Callahan, C. M.; Cheviron, Z. A.; Good, J. M.
10.1101/2020.09.15.298893 — evolutionary biology — Posted on 2020-09-16
1987 Bromelain Inhibits SARS-CoV-2 Infection in VeroE6 Cells
Sagar, S.; Rathinavel, A. K.; Lutz, W. E.; Struble, L. R.; Khurana, S.; Schnaubelt, A. T.; Mishra, N. K.; Guda, C.; Broadhurst, M. J.; Reid, S. P.; Bayles, K. W.; Borgstahl, G. E. O.; Radhakrishnan, P.
10.1101/2020.09.16.297366 — microbiology — Posted on 2020-09-16
1988 Human cerebrospinal fluids have no microbiome but can contain potential pathogens
Kang, Y.; Ji, X.; Guo, L.; Xia, H.; Yang, X.; Zhang, W.; Wei, H.; Guan, Y.; Ye, K.; Zhao, G.
10.1101/2020.09.16.299065 — microbiology — Posted on 2020-09-16
1989 Transcriptional activity differentiates families of Marine Group II Euryarchaeota in the coastal ocean
Damashek, J.; Okotie-Oyekan, A. O.; Gifford, S. M.; Vorobev, A.; Moran, M. A.; Hollibaugh, J. T.
10.1101/2020.09.16.299958 — microbiology — Posted on 2020-09-16
1990 Baricitinib treatment resolves lower airway inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques
Hoang, T. N.; Pino, M.; Boddapati, A. K.; Viox, E. G.; Starke, C. E.; Upadhyay, A. A.; Gumber, S.; Busman-Sahay, K.; Strongin, Z.; Harper, J. L.; Tharp, G. K.; Pellegrini, K. L.; Kirejczyk, S.; Zandi, K.; Tao, S.; Horton, T. R.; Beagle, E. N.; Mahar, E. A.; Lee, M. Y.; Cohen, J.; Jean, S.; Wood, J. S.; Connor-Stroud, F.; Stammen, R. L.; Delmas, O. M.; Wang, S.; Cooney, K. A.; Sayegh, M. N.; Wang, L.; Weiskopf, D.; Filev, P. D.; Waggoner, J.; Piantadosi, A.; Kasturi, S. P.; Al-Shakhshir, H.; Ribeiro, S. P.; Sekaly, R. P.; Levit, R. D.; Estes, J. D.; Vanderford, T. H.; Schinazi, R. F.; Bosinger,
10.1101/2020.09.16.300277 — immunology — Posted on 2020-09-16
1991 Natural sensory context drives diverse brain-wide activity during C. elegans mating
Susoy, V.; Hung, W.; Witvliet, D.; Whitener, J. E.; Wu, M.; Graham, B. J.; Zhen, M.; Venkatachalam, V.; Samuel, A. D. T.
10.1101/2020.09.09.289454 — neuroscience — Posted on 2020-09-16
1993 No evidence of impaired sensorimotor adaptation in Complex Regional Pain Syndrome
Vitterso, A. D.; Buckingham, G.; Ten Brink, A. F.; Halicka, M.; Proulx, M. J.; Bultitude, J. H.
10.1101/2020.09.08.287862 — neuroscience — Posted on 2020-09-16
1995 Closed loop enhancement and neural decoding of human cognitive control
basu, i.; yousefi, a.; Crocker, B.; Zelmann, R.; Paulk, A. C.; Peled, N.; Ellard, K. K.; Weisholtz, D. S.; Cosgrove, G. R.; Deckersbach, T.; Eden, U.; Eskandar, E. N.; Dougherty, D. D.; Cash, S. S. S.; Widge, A. S.
10.1101/2020.04.24.059964 — bioengineering — Posted on 2020-09-16
2000 Synthetic Agonist of Growth Hormone-Releasing Hormone as Novel Treatment for Heart Failure with Preserved Ejection Fraction
Dulce, R. A.; Kanashiro-Takeuchi, R. M.; Takeuchi, L. M.; Salerno, A. G.; Kulandavelu, S.; Balkan, W.; Zuttion, M. S.; Cai, R.; Schally, A. V.; Hare, J. M.
10.1101/2020.02.28.967000 — cell biology — Posted on 2020-09-16
2004 Spatial Patterns for Discriminative Estimation (SPADE)
Llera Arenas, A.; Chauvin, R.; Mulders, P. C.; Naaijen, J.; Mennes, M.; Beckmann, C. F.
10.1101/746891 — neuroscience — Posted on 2020-09-16
2005 A visual pathway for skylight polarization processing in Drosophila
Hardcastle, B. J.; Omoto, J. J.; Kandimalla, P.; Nguyen, B.-C. M.; Keles, M. F.; Boyd, N. K.; Hartenstein, V.; Frye, M. A.
10.1101/2020.09.10.291955 — neuroscience — Posted on 2020-09-16
2006 DeepCell Kiosk: Scaling deep learning-enabled cellular image analysis with Kubernetes
Bannon, D.; Moen, E.; Schwartz, M.; Borba, E.; Kudo, T.; Greenwald, N.; Vijayakumar, V.; Chang, B.; Pao, E.; Osterman, E.; Graf, W.; Van Valen, D.
10.1101/505032 — systems biology — Posted on 2020-09-16
2007 Small molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer's disease
Heller, G. T.; Aprile, F. A.; Michaels, T. C.; Limbocker, R.; Perni, M.; Ruggeri, F. S.; Mannini, B.; Lohr, T.; Bonomi, M.; Camilloni, C.; De Simone, A.; Felli, I. C.; Pierattelli, R.; Knowles, T. P.; Dobson, C. M.; Vendruscolo, M.
10.1101/729392 — biophysics — Posted on 2020-09-16
2008 Electrical Impedance Spectroscopy to easily assess structural changes in dominant versus auxiliary upper arms due to pathophysiological events.
Dell'Osa, A. H.; Fois, A.; Mela, Q.; Loviselli, A.; Capone, A.; Marongiu, G.; Tocco, F.; Concu, A.; Velluzzi, F.
10.1101/622944 — bioengineering — Posted on 2020-09-16
2009 Replication dynamics and cytotoxicity of SARS-CoV-2 Swedish isolate in commonly used laboratory cell lines
Saccon, E.; Krishnan, S.; Vinhas, B. S.; Byrareddy, S.; Mirazimi, A.; Neogi, U.; Gupta, S.
10.1101/2020.08.28.271684 — microbiology — Posted on 2020-09-16
2011 Citizen Scientists Create an Exascale Computer to Combat COVID-19
Zimmerman, M. I.; Porter, J. R.; Ward, M. D.; Singh, S.; Vithani, N.; Meller, A.; Mallimadugula, U. L.; Kuhn, C. E.; Borowsky, J. H.; Wiewiora, R. P.; Hurley, M. F. D.; Harbison, A. M.; Fogarty, C. A.; Coffland, J. E.; Fadda, E.; Voelz, V. A.; Chodera, J. D.; Bowman, G. R.
10.1101/2020.06.27.175430 — biophysics — Posted on 2020-09-16
2016 Characterisation of protease activity during SARS-CoV-2 infection identifies novel viral cleavage sites and cellular targets for drug repurposing
Meyer, B.; Chiaravalli, J.; Brownridge, P.; Bryne, D. P.; Daly, L. A.; Agou, F.; Eyers, C. E.; Eyers, P. A.; Vignuzzi, M.; Emmott, E.
10.1101/2020.09.16.297945 — microbiology — Posted on 2020-09-16
2017 Mouse model for testing SARS-CoV-2 antivirals: Pharmacokinetics
Scherf-Clavel, O.; Kinzig, M.; Friedl, B.; Kaczmarek, E.; Feja, M.; Gernert, M.; Richter, F.; Hoehl, R.; Nau, R.; Holzgrabe, U.; Soergel, F.
10.1101/2020.09.16.299537 — systems biology — Posted on 2020-09-16
2018 The flexibility of ACE2 in the context of SARS-CoV-2 infection
Barros, E. P.; Casalino, L.; Gaieb, Z.; Dommer, A. C.; Wang, Y.; Fallon, L.; Raguette, L.; Belfon, K.; Simmerling, C. L.; Amaro, R. E.
10.1101/2020.09.16.300459 — biophysics — Posted on 2020-09-16
2020 High affinity modified ACE2 receptors prevent SARS-CoV-2 infection
Higuchi, Y.; Suzuki, T.; Arimori, T.; Ikemura, N.; Kirita, Y.; Ohgitani, E.; Mazda, O.; Motooka, D.; Nakamura, S.; Matsuura, Y.; Matoba, S.; Okamoto, T.; Takagi, J.; Hoshino, A.
10.1101/2020.09.16.299891 — bioengineering — Posted on 2020-09-16
2024 Evolutionary dynamics of transposable elements in bdelloid rotifers
Nowell, R. W.; Wilson, C. G.; Almeida, P.; Schiffer, P. H.; Fontaneto, D.; Becks, L.; Rodriguez, F.; Arkhipova, I. R.; Barraclough, T. G.
10.1101/2020.09.15.297952 — evolutionary biology — Posted on 2020-09-16
2027 Inferring the heritability of large-scale functional networks with a multivariate ACE modeling approach
Ribeiro, F. L.; dos Santos, F. R. C.; Sato, J. R.; Pinaya, W. H. L.; Biazoli Junior, C. E.
10.1101/437335 — neuroscience — Posted on 2020-09-16
2029 CDNF rescues motor neurons in three animal models of ALS by targeting ER stress
De Lorenzo, F.; Luningschror, P.; Nam, J.; Pilotto, F.; Galli, E.; Lindholm, P.; Rudt von Collenberg, C.; Tii Mungwa, S.; Kauder, J.; Jablonka, S.; Petri, S.; Lindholm, D.; Saxena, S.; Sendtner, M.; Saarma, M.; Voutilainen, M. H.
10.1101/2020.05.05.078618 — neuroscience — Posted on 2020-09-16
2032 Genome-scale phylogenetic analyses confirm Olpidium as the closest living zoosporic fungus to the non-flagellated, terrestrial fungi
Chang, Y.; Rochon, D.; Sekimoto, S.; Wang, Y.; Chovatia, M.; Sandor, L.; Salamov, A.; Grigoriev, I. V.; Stajich, J. E.; Spatafora, J. W.
10.1101/2020.09.16.298935 — evolutionary biology — Posted on 2020-09-16
2033 Contrasting impacts of urban and farmland cover on flying insect biomass
Svenningsen, C. S.; Bowler, D. E.; Hecker, S.; Bladt, J.; Grescho, V.; van Dam, N. M.; Dauber, J.; Eichenberg, D.; Ejrnaes, R.; Flojgaard, C.; Frenzel, M.; Froslev, T. G.; Hansen, A. J.; Heilmann-Clausen, J.; Huang, Y.; Larsen, J. C.; Menger, J.; Nayan, N. L. B. M.; Pedersen, L. B.; Richter, A.; Dunn, R. R.; Tottrup, A. P.; Bonn, A.
10.1101/2020.09.16.299404 — ecology — Posted on 2020-09-16
2034 Cenote-Taker 2 Democratizes Virus Discovery and Sequence Annotation
Tisza, M. J.; Belford, A. K.; Dominguez Huerta, G.; Bolduc, B.; Sullivan, M. B.; Buck, C. B.
10.1101/2020.09.15.298943 — microbiology — Posted on 2020-09-16
2036 Alpha fluctuations regulate the accrual of visual information to awareness
Torralba Cuello, M.; Drew, A.; Sabate San Jose, A.; Moris Fernandez, L.; Soto Faraco, S.
10.1101/2020.09.16.298166 — neuroscience — Posted on 2020-09-16
2042 Discovery of a Novel Polymer for Xeno-free, Long-term Culture of Human Pluripotent Stem Cell Expansion
Thorpe, J.; Nasir, A.; Burroughs, L.; Meurs, J.; Pijuan-Galito, S.; Irvine, D. J.; Alexander, M. R.; Denning, C.
10.1101/2020.09.16.298810 — synthetic biology — Posted on 2020-09-16
2044 IM30 IDPs form a membrane protective carpet upon super-complex disassembly
Junglas, B.; Orru, R.; Axt, A.; Siebenaller, C.; Steinchen, W.; Heidrich, J.; Hellmich, U. A.; Hellmann, N.; Wolf, E.; Weber, S. A. L.; Schneider, D.
10.1101/2020.09.16.299396 — biophysics — Posted on 2020-09-16
2048 Comprehensive characterization of tissue-specific chromatin accessibility in L2 Caenorhabditis elegans nematodes
Durham, T. J.; Daza, R. M.; Gevirtzman, L.; Cusanovich, D.; Noble, W. S.; Shendure, J.; Waterston, R. H.
10.1101/2020.09.15.299123 — genomics — Posted on 2020-09-16
2051 Gpr125 Plays Critical Roles in Lacrimal Myoepithelia and Tear Film
Spina, E.; Handlin, R.; Simundza, J.; Incassati, A.; Faiq, M.; Sainulabdeen, A.; Chan, K. C.; Cowin, P.
10.1101/2020.09.15.296749 — developmental biology — Posted on 2020-09-16
2055 Mean-field modeling of brain-scale dynamics for the evaluation of EEG source-space networks
Allouch, S.; Yochum, M.; Kabbara, A.; Duprez, J.; Khalil, M.; Wendling, F.; HASSAN, M.; Modolo, J.
10.1101/2020.09.16.299305 — neuroscience — Posted on 2020-09-16
2059 X chromosome-dependent disruption of placental regulatory networks in hybrid dwarf hamsters
Brekke, T. D.; Moore, E. C.; Callahan, C. M.; Campbell-Staton, S. C.; Cheviron, Z. A.; Good, J. M.
10.1101/2020.09.15.298893 — evolutionary biology — Posted on 2020-09-16
2062 ATP activation of peritubular cells drives testicular sperm transport
Spehr, M.; Fleck, D.; Kenzler, L.; Mundt, N.; Strauch, M.; Uesaka, N.; Moosmann, R.; Bruentgens, F.; Missel, A.; Mayerhofer, A.; Merhof, D.; Spehr, J.
10.1101/2020.09.15.298299 — cell biology — Posted on 2020-09-16
2063 SARS-CoV-2 protein Nsp1 alters actomyosin cytoskeleton and phenocopies arrhythmogenic cardiomyopathy-related PKP2 mutant
Marquez-Lopez, C.; Roche-Molina, M.; Garcia-Quintans, N.; Sacristan, S.; Siniscalco, D.; Gonzalez-Guerra, A.; Camafeita, E.; Lytvyn, M.; Guillen, M. I.; Sanz-Rosa, D.; Martin-Perez, D.; Sanchez-Ramos, C.; Garcia, R.; Bernal, J. A.
10.1101/2020.09.14.296178 — molecular biology — Posted on 2020-09-16
2064 Characterization of the habitat- and season-independent increase in fungal biomass induced by the invasive giant goldenrod and its impact on the fungivorous nematode community
Harkes, P.; van Heumen, L. J. M.; van Elsen, S. J. J.; Mooijman, P. J. W.; Quist, C. W.; Vervoort, M. T. W.; Gort, G.; Holterman, M. H. M.; Helder, J.
10.1101/2020.09.16.274845 — molecular biology — Posted on 2020-09-16
2065 Essential gene analysis in Acinetobacter baumannii by high-density transposon mutagenesis and CRISPR interference
Bai, J.; Dai, Y.; Farinha, A.; Tang, A. Y.; Syal, S.; Vargas-Cuebas, G.; Surujon, D.; Isberg, R. R.; van Opijnen, T.; Geisinger, E.
10.1101/2020.09.15.299016 — microbiology — Posted on 2020-09-16
2066 Hymenoptera associated eukaryotic virome lacks host specificity
Deboutte, W.; Beller, L.; Yinda, K. C.; Shi, C.; Smets, L.; Vanmechelen, B.; Conceicao-Neto, N.; Dallmeier, K.; Maes, P.; de Graaf, D. C.; Matthijnssens, J.
10.1101/2020.09.15.298042 — microbiology — Posted on 2020-09-16
2067 A transcriptomic taxonomy of Drosophila circadian neurons around the clock
Ma, D.; Przybylski, D.; Abruzzi, K. C.; Schlichting, M.; Li, Q.; Long, X.; Rosbash, M.
10.1101/2020.09.15.297051 — neuroscience — Posted on 2020-09-16
2069 Calcium imaging and the curse of negativity
Vanwalleghem, G. C.; Scott, E. C.; Constantin, L.
10.1101/2020.09.15.298885 — neuroscience — Posted on 2020-09-16
2072 Predicting MEG resting-state functional connectivity using microstructural information
Messaritaki, E.; Foley, S.; Schiavi, S.; Magazzini, L.; Routley, B.; Jones, D. K.; Singh, K. D.
10.1101/2020.09.15.298307 — neuroscience — Posted on 2020-09-16
2083 Structural Coordinates: A novel approach to predict protein backbone conformation
Milchevskaya, V.; Nikitin, A. M.; Lukshin, S. A.; Filatov, I. V.; Kravatsky, Y. V.; Tumanyan, V. G.; Esipova, N. G.; Milchevskiy, Y. V.
10.1101/2020.09.15.297747 — bioinformatics — Posted on 2020-09-16
2084 DMA-tudor interaction modules control the specificity of in vivo condensates
Courchaine, E. M.; Barentine, A. E. S.; Straube, K.; Bewersdorf, J.; Neugebauer, K. M.
10.1101/2020.09.15.297994 — biochemistry — Posted on 2020-09-16
2085 The sugarcane and sorghum kinomes: insights into evolutionary expansion and diversification
Aono, A. H.; Pimenta, R. J. G.; Garcia, A. L. B.; Correr, F. H.; Kenichi Hosaka, G.; Carrasco, M. M.; Cardoso-Silva, C. B.; Mancini, M. C.; Sforca, D. A.; dos Santos, L. B.; Nagai, J. S.; Pinto, L. R.; Landell, M. G. d. A.; Carneiro, M. S.; Balsalobre, T. W.; Quiles, M. G.; Pereira, W. A.; Margarido, G. R. A.; de Souza, A. P.
10.1101/2020.09.15.298612 — genomics — Posted on 2020-09-16
2089 Parental influences on offspring education: indirect genetic effects of non-cognitive skills
Demange, P. A.; Hottenga, J. J.; Abdellaoui, A.; Malanchini, M.; Domingue, B. W.; de Zeeuw, E. L.; Rimfeld, K.; Eley, T.; Boomsma, D. I.; van Bergen, E.; Breen, G.; Nivard, M. G.; Cheesman, R.
10.1101/2020.09.15.296236 — genetics — Posted on 2020-09-16
2090 Evolutionary dynamics of transposable elements in bdelloid rotifers
Nowell, R. W.; Wilson, C. G.; Almeida, P.; Schiffer, P. H.; Fontaneto, D.; Becks, L.; Rodriguez, F.; Arkhipova, I. R.; Barraclough, T. G.
10.1101/2020.09.15.297952 — evolutionary biology — Posted on 2020-09-16
2094 Status of the pillar coral Dendrogyra cylindrus in Los Roques National Park, Southern Caribbean
Cavada-Blanco, F.; Cappelletto, J.; Agudo-Adriani, E.; Martinez, S.; Croquer, A.; Rodriguez, J. P.
10.1101/2020.09.15.297770 — ecology — Posted on 2020-09-16
2100 TMS cortical mapping of multiple muscles: absolute and relative test-retest reliability
Nazarova, M.; Novikov, P.; Ivanina, E.; Kozlova, K.; Dobrynina, L. A.; Nikulin, V. V.
10.1101/2020.09.15.298794 — neuroscience — Posted on 2020-09-16
2102 The 5α-reductase inhibitor finasteride reduces opioid self-administration
Bosse, G. D.; Cadeddu, R.; Floris, G.; Farero, R.; Vigato, E.; Lee, J.; Zhang, T.; Gaikwad, N.; Keefe, K.; Phillips, P. E. M.; Bortolato, M.; Peterson, R. T.
10.1101/2020.09.15.291609 — neuroscience — Posted on 2020-09-16
2108 RuBisCO adaptation is more limited by phylogenetic constraint than by catalytic trade-off
Bouvier, J. W.; Emms, D. M.; Rhodes, T.; Nielsen, J. R.; Bolton, J. S.; Eddershaw, A.; Brasnett, A.; Unitt, A.; Whitney, S. M.; Kelly, S.
10.1101/2020.09.15.298075 — plant biology — Posted on 2020-09-16
2110 Asprosin Neutralizing Antibodies as a Treatment for Metabolic Syndrome
Mishra, I.; Duerrschmid, C.; Ku, Z.; Xie, W.; Silva, E. S.; Hoffman, J.; Zhang, N.; An, Z.; Chopra, A.
10.1101/2020.09.15.298489 — physiology — Posted on 2020-09-16
2112 Engineering, Generation and Preliminary Characterization of a Humanized Porcine Sickle Cell Disease Animal Model
Franks, T. M.; Haugabook, S. J.; Ottinger, E. A.; Vermillion, M. S.; Pawlik, K. M.; Townes, T. M.; Rogers, C. S.
10.1101/2020.09.15.291864 — physiology — Posted on 2020-09-16
2116 Dynamic analysis of sugar metabolism reveals the mechanisms of action of synthetic sugar analogs
Scherpenzeel, M. v.; Conte, F.; Bull, C.; Ashikov, A.; Hermans, E.; Willems, A.; Tol, W. v.; Kragt, E.; Moret, E.; Heise, T.; Langereis, J.; Rossing, E.; Zimmermann, M.; Rubio-Gozalbo, E. M.; Jonge, M. d.; Adema, G.; Zamboni, N.; Boltje, T.; Lefeber, D.
10.1101/2020.09.15.288712 — biochemistry — Posted on 2020-09-16
2117 Identifying HIV-1 RNA splice variant protein interactomes using HyPR-MSSV
Knoener, R.; Evans, E.; Becker, J. T.; Scalf, M.; Benner, B.; Sherer, N. M.; Smith, L. M.
10.1101/2020.09.15.298190 — biochemistry — Posted on 2020-09-16
2119 Whole-genome sequencing of 1,171 elderly admixed individuals from the largest Latin American metropolis (Sao Paulo, Brazil)
Naslavsky, M. S.; Scliar, M. O.; Yamamoto, G. L.; Wang, J. Y.; Zverinova, S.; Karp, T.; Nunes, K.; Ceroni, J. R. M.; Carvalho, D. L.; Simoes, C. E. S.; Bozoklian, D.; Silva, N. S.; Souza, A. S.; Andrade, H. S.; Passos, M. R.; Castro, C. F.; Mendes-Junior, C. T.; Mercuri, R. L.; Miller, T. L.; Buzzo, J. L.; Rego, F. O.; Araujo, N. M.; Magalhaes, W. C.; Mingroni-Netto, R. C.; Borda, V.; Guio, H.; Barreto, M. L.; Lima-Costa, M. F.; Horta, B. L.; Tarazona-Santos, E.; Meyer, D.; Galante, P. A.; Guryev, V.; Castelli, E. C.; Duarte, Y. A.; Passos-Bueno, M. R.; Zatz, M.
10.1101/2020.09.15.298026 — genomics — Posted on 2020-09-16
2120 A contiguous de novo genome assembly of sugar beet EL10 (Beta vulgaris L.)
McGrath, J. M.; Funk, A.; Galewski, P.; Ou, S.; Townsend, B. J.; Davenport, K.; Daligault, H.; Johnson, S.; Lee, J.; Hastie, A. R.; Darracq, A.; Willems, G.; Barnes, S.; Liachko, I.; Sullivan, S.; Koren, S.; Phillippy, A.; Wang, J.; Liu, T.; Pulman, J. A.; Childs, K.; Yocum, A.; Fermin, D.; Mutasa-Gottgens, E.; Stevanato, P.; Taguchi, K.; Dorn, K.
10.1101/2020.09.15.298315 — genomics — Posted on 2020-09-16
2121 SNP heritability: What are we estimating?
Rawlik, K.; Canela-Xandri, O.; Woolliams, J.; Tenesa, A.
10.1101/2020.09.15.276121 — genetics — Posted on 2020-09-16
2123 SUMOylation regulates protein cargo in Astrocyte-derived small extracellular vesicles
Fernandez, A.; Mendez, M.; Santis, O.; Corvalan, K.; Gomez, M.-T.; Landgraf, P.; Kaehne, T.; Rojas-Fernandez, A.; Wyneken, U.
10.1101/2020.09.15.298554 — cell biology — Posted on 2020-09-16
2125 Attention network modulation via tRNS correlates with attention gain
Conto, F.; Edwards, G.; Tyler, S.; Parrott, D.; Grossman, E.; Battelli, L.
10.1101/2020.09.15.298240 — neuroscience — Posted on 2020-09-16
2127 Non-redundant functions of H2A.Z.1 and H2A.Z.2 in chromosome segregation and cell cycle progression.
Gil, R. S.; de Castro, I. J.; Amin, H. A.; Spanos, C.; Vinviotti, V.; Rappsilber, J.; Sisu, C.; Vagnarelli, P.
10.1101/2020.09.15.297671 — cell biology — Posted on 2020-09-15
2128 DETECTION AND MOLECULAR CHARACTERIZATION OF ROTAVIRUS AND PICOBIRNAVIRUS IN WILD AVIANS FROM AMAZON FOREST
Duarte Junior, J. W. B.; Chagas, E. H. N.; serra, A. C. S.; souto, L. C. d. S.; da Penha Junior, E. T.; bandeira, R. d. S.; e Guimaraes, R. J. d. P. S.; Oliveira, H. G. d. S.; sousa, T. K. S.; lopes, C. T. d. A.; domingues, S. F. S.; Malik, Y. S.; Salvarani, F. M.; Mascarenhas, J. D. P.
10.1101/2020.09.15.297689 — molecular biology — Posted on 2020-09-15
2131 Converting Microwave Ovens into Plasma-Generating Decontamination Units for N-95 Respirators
Ruzic, D. N.; Oh, C.; Puthussery, J. V.; Patel, D.; Jeckell, Z.; Verma, V.; Nguyen, T. H.
10.1101/2020.09.15.297630 — bioengineering — Posted on 2020-09-15
2132 Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer
Kumar, R.; Deshpande, S.; Sewall, L. M.; Ozorowski, G.; Cottrell, C. A.; Lee, W.-H.; Holden, L. G.; Richey, S. T.; Chandrawacar, A.; Dhiman, K.; Ashish, A.; Kumar, V.; Ahmed, S.; Hingankar, N.; Kumar, N.; Murugavel, K. G.; Srikrishnan, A. K.; Sok, D.; Ward, A. B.; Bhattacharya, J.
10.1101/2020.09.15.297697 — immunology — Posted on 2020-09-15
2134 Mapping Brain-Behavior Space Relationships Along the Psychosis Spectrum
Ji, J. L.; Helmer, M.; Fonteneau, C.; Burt, J. B.; Tamayo, Z.; Demsar, J.; Adkinson, B.; Savic, A.; Preller, K.; Moujaes, F.; Vollenweider, F. X.; Martin, W.; Repovs, G.; Murray, J. D.; Anticevic, A.
10.1101/2020.09.15.267310 — neuroscience — Posted on 2020-09-15
2135 The Detailed Organization of the Human Cerebellum Estimated by Intrinsic Functional Connectivity Within the Individual
Xue, A.; Kong, R.; Yang, Q.; Eldaief, M. C.; Angeli, P.; DiNicola, L. M.; Braga, R. M.; Buckner, R. L.; Yeo, B. T. T.
10.1101/2020.09.15.297911 — neuroscience — Posted on 2020-09-15
2136 CROssBAR: Comprehensive Resource of Biomedical Relations with Deep Learning Applications and Knowledge Graph Representations
Dogan, T.; Atas, H.; Joshi, V.; Atakan, A.; Rifaioglu, A. S.; Nalbat, E.; Nightingale, A.; Saidi, R.; Volynkin, V.; Zellner, H.; Cetin-Atalay, R.; Martin, M.; Atalay, V.
10.1101/2020.09.14.296889 — bioinformatics — Posted on 2020-09-15
2138 An Engineered Genetic Circuit for Lactose Intolerance Alleviation Coupled with Gut Microbiota Recovery
Cheng, M.; Cheng, Z.; Yu, Y.; Liu, W.; Li, R.; Guo, Z.; Qin, J.; Zeng, Z.; Di, L.; Mo, Y.; Pan, C.; Liang, Y.; Li, J.; Tong, Y.-G.; Yan, Y.; Zhan, Y.; Ning, K.
10.1101/2020.09.15.297564 — bioengineering — Posted on 2020-09-15
2142 Proteomic analysis of metabolic pathways shows chloroplast-mitochondria cross-talk in a Cu-limited diatom
Hippmann, A.; Schuback, N.; Moon, K.-M.; McCrow, J. P.; Allen, A. E.; Foster, L. J.; Green, B. R.; Maldonado, M. T.
10.1101/2020.09.15.298752 — microbiology — Posted on 2020-09-15
2147 Early Emergence and Long-Term Persistence of HIV-Infected T Cell Clones in Children
Bale, M. J.; Katusiime, M. G.; Wells, D.; Wu, X.; Spindler, J.; Halvas, E. K.; Cyktor, J. C.; Wiegand, A.; Shao, W.; Cotton, M. F.; Hughes, S. H.; Mellors, J. W.; Coffin, J. M.; Van Zyl, G. U.; Kearney, M. F.
10.1101/2020.09.15.298406 — microbiology — Posted on 2020-09-15
2148 LOX-1+ immature neutrophils predict severe COVID-19 patients at risk of thrombotic complications
Combadiere, B.; Adam, L.; Quentric, P.; Rosenbaum, P.; Dorgham, K.; Bonduelle, O.; Parizot, C.; Sauce, D.; Mayaux, J.; Luyt, C.-E.; Boissonnas, A.; Amoura, Z.; Pourcher, V.; Miyara, M.; Gorochov, G.; Guihot, A.; Combadiere, C.
10.1101/2020.09.15.293100 — immunology — Posted on 2020-09-15
2149 TDP-43 stabilizes transcripts encoding stress granule protein G3BP1: potential relevance to ALS/FTD
Sidibe, H.; Khalfallah, Y.; Xiao, S.; Gomez, N.; Tank, E. M. H.; Di Tomasso, G.; Bareke, E.; Aulas, A.; McKeever, P. M.; Melamed, Z.; Destroismaisons, L.; Deshaies, J.-E.; Zinman, L.; Parker, J. A.; Legault, P.; Tetreault, M.; Barmada, S. J.; Robertson, J.; Vande Velde, C.
10.1101/2020.09.15.298455 — neuroscience — Posted on 2020-09-15
2150 The piRNA pathway sustains adult neurogenesis by repressing protein synthesis
Gasperini, C.; Pelizzoli, R.; Lo Van, A.; Mangoni, D.; Cossu, R. M.; Pascarella, G.; Bianchini, P.; Bielefeld, P.; Scarpato, M.; Pons-Espinal, M.; Sanges, R.; Diaspro, A.; Fitzsimons, C. P.; Carninci, P. P.; Gustincich, S.; De Pietri Tonelli, D.
10.1101/2020.09.15.297739 — neuroscience — Posted on 2020-09-15
2152 Predictive regulatory and metabolic network models for systems analysis of Clostridioides difficile
Arrieta-Ortiz, M. L.; Immanuel, S. R. C.; Turkarslan, S.; Wu, W.-J.; Girinathan, B. P.; Worley, J. N.; DiBenedetto, N.; Soutourina, O.; Peltier, J.; Dupuy, B.; Bry, L.; Baliga, N. S.
10.1101/2020.09.14.297382 — systems biology — Posted on 2020-09-15
2153 Antifungal benzimidazoles disrupt vasculature by targeting one of nine β-tubulins
Garge, R. K.; Cha, H. J.; Lee, C.; Gollihar, J. D.; Kachroo, A. H.; Wallingford, J. B.; Marcotte, E. M.
10.1101/2020.09.15.298828 — systems biology — Posted on 2020-09-15
2155 Limited haplotype diversity underlies polygenic trait architecture across 70 years of wheat breeding
Scott, M. F.; Fradgley, N. S.; Bentley, A.; Brabbs, T.; Corke, F.; Gardner, K.; Horsnell, R.; Howell, P.; Ladejobi, O.; Mackay, I. S.; Mott, R.; Cockram, J.
10.1101/2020.09.15.296533 — genomics — Posted on 2020-09-15
2158 COPB2 haploinsufficiency causes a coatopathy with osteoporosis and developmental delay
Marom, R.; Burrage, L. C.; Clement, A.; Blanco-Sanchez, B.; Venditti, R.; Jain, M.; Grafe, I.; Scott, D.; Rosenfeld, J. A.; Sutton, V. R.; Shinawi, M.; Mirzaa, G.; DeVile, C.; Roberts, R.; Calder, A. D.; Allgrove, J.; Lanza, D. G.; Li, X.; Joeng, K. S.; Lee, Y.-C.; Song, I.-W.; Sliepka, J. M.; Batkovshyte, D.; Jin, Z.; Dawson, B. C.; Chen, S.; Chen, Y.; Jiang, M.-M.; Munivez, E. M.; Tran, A. A.; Emrick, L. T.; Murdock, D. R.; Hanchard, N. A.; Zapata, G. E.; Mehta, N. R.; Weis, M. A.; Kuzawa, C.; Scott, A.; Tremp, B. A.; Phillips, J. B.; Wegner, J.; Taylor-Miller, T.; Gibbs, R. A.; muzny, d. m.
10.1101/2020.09.14.297234 — genetics — Posted on 2020-09-15
2159 Endozoochory by parrotfish replenishes reefs with coral-associated microbiome
Velasquez-Rodriguez, T. M.; Zuluaga-Arias, C.; Montano, S. M.; Gonzalez, J. M.; Sanchez, J. A.
10.1101/2020.09.15.298737 — ecology — Posted on 2020-09-15
2160 Impact of temporal pH fluctuations on the coexistence of nasal bacteria
Dedrick, S.; Akbari, M. J.; Dyckman, S.; Zhao, N.; Liu, Y.-Y.; Momeni, B.
10.1101/2020.09.15.298778 — ecology — Posted on 2020-09-15
2161 Emergence and expansion of highly infectious spike:D614G mutant SARS-CoV-2 in central India
Sharma, S.; Dash, P. K.; Sharma, S. K.; Srivastava, A.; Kumar, J. S.; Karothia, B. S.; Chelvam, K. T.; Singh, S.; Gupta, A.; Yadav, R. G.; Yadav, R.; S, G. T.; Kushwah, P.; Bhushan, R.; Nagar, D. P.; Nandan, M.; Kumar, S.; Thavaselvam, D.; Dubey, D. K.
10.1101/2020.09.15.297846 — molecular biology — Posted on 2020-09-15
2163 The Anti-histamine Azelastine, Identified by Computational Drug Repurposing, Inhibits SARS-CoV-2 Infection in Reconstituted Human Nasal Tissue In Vitro
Konrat, R.; Papp, H.; Szijarto, V.; Gesell, T.; Nagy, G.; Madai, M.; Zeghbib, S.; Kuczmog, A.; Lanszki, Z.; Helyes, Z.; Kemenesi, G.; Jakab, F.; Nagy, E.
10.1101/2020.09.15.296228 — microbiology — Posted on 2020-09-15
2166 Antibody potency, effector function and combinations in protection from SARS-CoV-2 infection in vivo
Schaefer, A.; Muecksch, F.; Lorenzi, J. C. C.; Leist, S. R.; Cipolla, M.; Bournazos, S.; Schmidt, F.; Gazumyan, A.; Baric, R. S.; Robbiani, D. F.; Hatziioannou, T.; Ravetch, J. V.; Bieniasz, P. D.; Nussenzweig, M. C.; Sheahan, T. P.
10.1101/2020.09.15.298067 — microbiology — Posted on 2020-09-15
2167 Antibody interference by a non-neutralizing antibody abrogates humoral protection against Plasmodium liver stage
Vijayan, K.; Chandrasekaran, R.; Trakhimets, O. T.; Brown, S. L.; Dambrauskas, N.; Zuck, M.; Visweswaran, G. R. R.; Watson, A.; Raappana, A.; Carbonetti, S.; Kelnhofer-Millevolte, L.; Glennon, E. K. K.; Postiglione, R.; Sather, D. N.; Kaushansky, A.
10.1101/2020.09.15.298471 — immunology — Posted on 2020-09-15
2168 Ceftazidime Is a Potential Drug to Inhibit SARS-CoV-2 Infection In Vitro by Blocking Spike Protein-ACE2 Interaction
Lin, C.; Li, Y.; Yuan, M.; Huang, M.; Liu, C.; Du, H.; Pan, X.; Wen, Y.; Xu, X.; Xu, C.; Chen, J.
10.1101/2020.09.14.295956 — immunology — Posted on 2020-09-15
2169 Generation of glucocorticoid resistant SARS-CoV-2 T-cells for adoptive cell therapy
Basar, R.; Uprety, N.; Ensley, E.; Daher, M.; Klein, K.; Martinez, F.; Aung, F.; Shanley, M.; Hu, B.; Gokdemir, E.; Mendt, M.; Reyes Silva, F.; Acharya, S.; Laskowski, T.; Muniz-Feliciano, L.; Banerjee, P.; Li, Y.; Li, S.; Melo Garcia, L.; Lin, P.; Shaim, H.; Yates, S. G.; Marin, D.; Kaur, I.; Rao, S.; Mak, D.; Lin, A.; Miao, Q.; Dou, J.; Chen, K.; Champlin, R.; Shpall, E. J.; Rezvani, K.
10.1101/2020.09.15.298547 — immunology — Posted on 2020-09-15
2172 Reduction of neuronal activity mediated by blood-vessel regression in the brain
Gao, X.; Li, J.-L.; Chen, X.; Ci, B.; Chen, F.; Lu, N.; Shen, B.; Zheng, L.; Jia, J.; Yi, Y.; Zhang, S.; Shi, Y.; Shi, K.; Propson, N. E.; Huang, Y.; Poinsatte, K.; Zhang, Z.; Yue, Y.; Bosco, D. B.; Lu, Y.-m.; Yang, S.-b.; Adams, R. H.; Lindner, V.; Huang, F.; Wu, L.-J.; Zheng, H.; Han, F.; Hippenmeyer, S.; Stowe, A. M.; Peng, B.; Margeta, M.; Wang, X.; Liu, Q.; Korbelin, J.; Trepel, M.; Lu, H.; Zhou, B. O.; Zhao, H.; Sun, W.; Bachoo, R. M.; Ge, W.-p.
10.1101/2020.09.15.262782 — neuroscience — Posted on 2020-09-15
2174 Enzymatic synthesis of fatty acid amides using microbial lipids as acyl group-donors and their biological activities
El-Baz, H. A.; Elazzazy, A. M.; Saleh, T. S.; Dritsas, P.; Mahyoub, J. A.; Baeshen, M. N.; Madian, H. R.; Alkhaled, M.; Aggelis, G.
10.1101/2020.09.13.295113 — biochemistry — Posted on 2020-09-15
2175 De novo virus inference and host prediction from metagenome using CRISPR spacers
Sugimoto, R.; Nishimura, L.; Thanh, P. N.; Ito, J.; Parrish, N. F.; Mori, H.; Kurokawa, K.; Nakaoka, H.; Inoue, I.
10.1101/2020.09.04.282665 — genomics — Posted on 2020-09-15
2176 A home and rescue gene drive efficiently spreads and persists in populations
Kandul, N. P.; Liu, J.; Bennett, J. B.; Marshall, J. M.; Akbari, O.
10.1101/2020.08.21.261610 — genetics — Posted on 2020-09-15
2178 Plxdc family members are novel receptors for the rhesus monkey rhadinovirus (RRV)
Grosskopf, A. K.; Schlagowski, S. C.; Fricke, T.; Ensser, A.; Desrosiers, R. C.; Hahn, A. S.
10.1101/2020.01.20.912246 — microbiology — Posted on 2020-09-15
2181 Chronic low-dose dioxin exposure accelerates high fat diet-induced hyperglycemia in female mice
Matteo, G.; Hoyeck, M. P.; Blair, H. L.; Zebarth, J.; Rick, K. R.; Williams, A.; Gagne, R.; Buick, J. K.; Yauk, C.; Bruin, J. E.
10.1101/2020.09.12.294587 — pharmacology and toxicology — Posted on 2020-09-15
2185 PreQual: An automated pipeline for integrated preprocessing and quality assurance of diffusion weighted MRI images
Cai, L. Y.; Yang, Q.; Hansen, C. B.; Nath, V.; Ramadass, K.; Johnson, G. W.; Conrad, B. N.; Boyd, B. D.; Begnoche, J. P.; Beason-Held, L. L.; Shafer, A. T.; Resnick, S. M.; Taylor, W. D.; Price, G. R.; Morgan, V. L.; Rogers, B. P.; Schilling, K. G.; Landman, B. A.
10.1101/2020.09.14.260240 — bioengineering — Posted on 2020-09-15
2186 Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors
Mavrommatis, L.; Jeong, H.-W.; Gomez-Giro, G.; Stehling, M.; Kienitz, M.-C.; Psathaki, O. E.; Bixel, G.; Morosan-Puopolo, G.; Gerovska, D.; Arauzo-Bravo, M. J.; Schwamborn, J. C.; Scholer, H. R.; Adams, R. H.; Vorgerd, M.; Brand-Saberi, B.; Zaehres, H.
10.1101/2020.09.14.295832 — bioengineering — Posted on 2020-09-15
2188 Deep learning and alignment of spatially-resolved whole transcriptomes of single cells in the mouse brain with Tangram
Biancalani, T.; Scalia, G.; Buffoni, L.; Avasthi, R.; Lu, Z.; Sanger, A.; Tokcan, N.; Vanderburg, C. R.; Segerstolpe, A.; Zhang, M.; Avraham-Davidi, I.; Vickovic, S.; Nitzan, M.; Ma, S.; Buenrostro, J. D.; Brown, N. B.; Fanelli, D.; Zhuang, X.; Macosko, E.; Regev, A.
10.1101/2020.08.29.272831 — genomics — Posted on 2020-09-15
2190 Strong effect of Penicillium roqueforti populations on volatile and metabolic compounds responsible for aromas, flavour and texture in blue cheeses
Caron, T.; Le Piver, M.; Peron, A.-C.; Lieben, P.; Lavigne, R.; Brunel, S.; Roueyre, D.; Place, M.; Bonnarme, P.; Giraud, T.; Branca, A.; Landaud, S.; Chassard, C.
10.1101/2020.03.02.974352 — evolutionary biology — Posted on 2020-09-15
2191 Control of dynamic cell behaviors during angiogenesis and anastomosis by Rasip 1
Lee, M.; Betz, C.; Paatero, I.; Schellinx, N. C.; Yin, J.; Wilson, C. W.; Ye, W.; Affolter, M.; Belting, H.-G.
10.1101/2020.08.27.269977 — developmental biology — Posted on 2020-09-15
2192 Loss of Nupr1 promotes engraftment by tuning the quiescence threshold of hematopoietic stem cell repository via regulating p53-checkpoint pathway
Wang, T.; Xia, C.; Weng, Q.; Wang, K.; Dong, Y.; Hao, S.; Dong, F.; Liu, X.; Liu, L.; Geng, Y.; Guan, Y.; Du, J.; Cheng, T.; Cheng, H.; Wang, J.
10.1101/2020.07.16.205898 — cell biology — Posted on 2020-09-15
2193 Transcriptional Feedback Disruption Yields Escape-Resistant Antivirals
Chaturvedi, S.; Wolf, M.; Vardi, N.; Du, K.; Glazier, J.; Ke, R.; Chan, M.; Perelson, A.; Weinberger, L.
10.1101/464495 — microbiology — Posted on 2020-09-15
2196 Nodal Fragility of Intracranial EEG Networks: Towards an EEG Fingerprint for the Seizure Onset Zone
Li, A.; Fitzgerald, Z.; Cajigas, I.; Brusko, D.; Claudio, A.; Jagid, J.; Kanner, A.; Hopp, J.; Chen, S.; Haagensen, J.; Johnson, E.; Crone, N.; Anderson, W.; Inati, S.; Zaghloul, K.; Bulacio, J.; Martinez, J.; Sarma, S.
10.1101/862797 — neuroscience — Posted on 2020-09-15
2205 Atypical TGF-beta Signaling Controls Neuronal Guidance in Caenorhabditis elegans
Baltaci, O.; Pedersen, M. E.; Sherry, T.; Handley, A.; Snieckute, G.; Haas, M.; Archer, S.; Pocock, R.
10.1101/2020.09.15.297556 — developmental biology — Posted on 2020-09-15
2206 Mouse fertilization triggers a conserved transcription program in one-cell embryos
Asami, M.; Lam, B. Y. H.; Hoffmann, M.; Suzuki, T.; Lu, X.; VerMilyea, M. D.; Yoshida, N.; Ma, M. K. L.; Rainbow, K.; Braun, S.; Patwary, N.; Yeo, G. S. H.; Klein, C. A.; Perry, A. C. F.
10.1101/2020.09.15.298018 — developmental biology — Posted on 2020-09-15
2207 Zika virus alters centrosome organization to suppress the innate immune response
Kodani, A.; Knopp, K.; Di Lullo, E.; Retallack, H.; Kriegstein, A.; DeRisi, J.; Reiter, J.
10.1101/2020.09.15.298083 — cell biology — Posted on 2020-09-15
2208 Generation of human induced trophoblast stem cells
CASTEL, G.; MEISTERMANN, D.; BRETIN, B.; FIRMIN, J.; BLIN, J.; LOUBERSAC, S.; BRUNEAU, A.; CHEVOLLEAU, S.; KILENS, S.; CHARIAU, C.; GAIGNERIE, A.; FRANCHETEAU, Q.; KAGAWA, H.; CHARPENTIER, E.; FLIPPE, L.; FRANCOIS - - CAMPION, V.; HAIDER, S.; DIETRICH, B.; KNOFLER, M.; ARIMA, T.; BOURDON, J.; RIVRON, N.; MASSON, D.; FOURNIER, T.; OKAE, H.; FREOUR, T.; DAVID, L.
10.1101/2020.09.15.298257 — cell biology — Posted on 2020-09-15
2209 Stable transplantation of human mitochondrial DNA by high-throughput, pressurized mitochondrial delivery
Sercel, A. J.; Patananan, A. N.; Man, T.; Wu, T.-H.; Yu, A. K.; Guyot, G. W.; Rabizadeh, S.; Niazi, K. R.; Chiou, P.-Y.; Teitell, M. A.
10.1101/2020.09.15.298174 — cell biology — Posted on 2020-09-15
2211 Refactoring the formicamycin biosynthetic gene cluster to make high-level producing strains and new molecules
Devine, R.; McDonald, H.; Qin, Z.; Arnold, C.; Noble, K.; Chandra, G.; Wilkinson, B. I.; Hutchings, M. I.
10.1101/2020.09.15.275776 — microbiology — Posted on 2020-09-15
2212 GP96 drives exacerbation of secondary bacterial pneumonia following influenza A virus infection
Sumitomo, T.; Nakata, M.; Nagase, S.; Takahara, Y.; Honda-Ogawa, M.; Mori, Y.; Yamaguchi, M.; Okamoto, S.; Kawabata, S.
10.1101/2020.09.14.297192 — microbiology — Posted on 2020-09-15
2215 Properties of the axial current of retinal ganglion cells at spike initiation
Goethals, S.; Sierksma, M. C.; Nicol, X.; Reaux-Le Goazigo, A.; Brette, R.
10.1101/2020.09.15.297937 — neuroscience — Posted on 2020-09-15
2218 Single-molecule measurements reveal that PARP1 condenses DNA by loop formation
Bell, N. A. W.; Haynes, P. J.; Brunner, K.; Maia de Oliveira, T.; Flocco, M.; Hoogenboom, B. W.; Molloy, J. E.
10.1101/2020.09.15.297887 — biophysics — Posted on 2020-09-15
2219 Wasp controls oriented migration of endothelial cells to achieve functional vascular patterning
Gerhardt, H.; Rosa, A.; Meier, K.; Giese, W.; Alt, S.; Klaus-Bergmann, A.; Edgar, L. T.; Bartels-Klein, E.; Collins, R.; Symborska-Mell, A.; Coxam, B.; Bernabeu, M. O.
10.1101/2020.09.15.296574 — developmental biology — Posted on 2020-09-15
2223 Transcriptional alterations in opioid use disorder reveal an interplay between neuroinflammation and synaptic remodeling
Seney, M.; Kim, S.-M.; Wang, J.; Hildebrand, M.; Xue, X.; Glausier, J.; Zong, W.; Shelton, M.; Phan, B.; Srinivasan, C.; Pfenning, A.; Tseng, G.; Lewis, D.; Freyberg, Z.; Logan, R.
10.1101/2020.09.14.296707 — neuroscience — Posted on 2020-09-15
2224 Functional Brain Networks and Alcohol Consumption: From the Naive State to Chronic Heavy Drinking
Rowland, J. A.; Stapleton-Kotloski, J. R.; Alberto, G. E.; Davenport, A. T.; Epperly, P. M.; Godwin, D. W.; Daunais, J. B.
10.1101/2020.09.14.296871 — neuroscience — Posted on 2020-09-15
2228 How to build a water-splitting machine: structural insights into photosystem II assembly
Zabret, J.; Bohn, S.; Schuller, S. K.; Arnolds, O.; Möller, M.; Meier-Credo, J.; Liauw, P.; Chan, A.; Tajkhorshid, E.; Langer, J. D.; Stoll, R.; Krieger-Liszkay, A.; Engel, B. D.; Rudack, T.; Schuller, J. M.; Nowaczyk, M. M.
10.1101/2020.09.14.294884 — plant biology — Posted on 2020-09-15
2229 Hyaluronic Acid Fuels Pancreatic Cancer Growth
Kim, P. K.; Halbrook, C. J.; Kerk, S. A.; Wisner, S.; Kremer, D. M.; Sajjakulnukit, P.; Hou, S. W.; Thurston, G.; Anand, A.; Yan, L.; Salamanca-Cardona, L.; Welling, S. D.; Zhang, L.; Pratt, M. R.; Keshari, K. R.; Ying, H.; Lyssiotis, C. A.
10.1101/2020.09.14.293803 — cancer biology — Posted on 2020-09-15
2230 Controlling T cells shape, mechanics and activation by micropatterning.
Sadoun, A.; Biarnes-Pelicot, M.; Ghesquiere-Dierickx, L.; Wu, A.; Theodoly, O.; Limozin, L.; Hamon, Y.; Puech, P.-H.
10.1101/2020.09.15.295964 — biophysics — Posted on 2020-09-15
2232 TIMEOR: a web-based tool to uncover temporal regulatory mechanisms from multi-omics data
Conard, A. M.; Goodman, N.; Hu, Y.; Perrimon, N.; Singh, R.; Lawrence, C.; Larschan, E.
10.1101/2020.09.14.296418 — bioinformatics — Posted on 2020-09-15
2234 PreQual: An automated pipeline for integrated preprocessing and quality assurance of diffusion weighted MRI images
Cai, L. Y.; Yang, Q.; Hansen, C. B.; Nath, V.; Ramadass, K.; Johnson, G. W.; Conrad, B. N.; Boyd, B. D.; Begnoche, J. P.; Beason-Held, L. L.; Shafer, A. T.; Resnick, S. M.; Taylor, W. D.; Price, G. R.; Morgan, V. L.; Rogers, B. P.; Schilling, K. G.; Landman, B. A.
10.1101/2020.09.14.260240 — bioengineering — Posted on 2020-09-15
2236 Hippocampus-lateral septum circuitry mediates foraging-related spatial memory in rats
Davis, E. A.; Liu, C. M.; Gianatiempo, I. H.; Suarez, A. N.; Cortella, A. M.; Hahn, J. D.; Kanoski, S. E.
10.1101/2020.06.16.155721 — neuroscience — Posted on 2020-09-15
2239 ComMet: A method for comparing metabolic states in genome-scale metabolic models
Sarathy, C.; Breuer, M.; Kutmon, M.; Adriaens, M. E.; Evelo, C. T.; Arts, I. C. W.
10.1101/2020.09.14.296145 — systems biology — Posted on 2020-09-15
2242 Tumor Edge-to-Core Transition Promotes Malignancy in Primary-to-Recurrent Glioblastoma Progression in a PLAGL1/CD109-mediated mechanism
Li, C.; Cho, H. J.; Yamashita, D.; Abdelrashid, M.; Chen, Q.; Bastola, S.; Chagoya, G.; A. Elsayed, G.; Komarova, S.; Ozaki, S.; Ohtsuka, Y.; Kunieda, T.; I Kornblum, H.; Kondo, T.; Nam, D.-H.; Nakano, I.
10.1101/2020.09.14.293753 — cancer biology — Posted on 2020-09-15
2243 Microfluidic Antibody Affinity Profiling for In-Solution Characterisation of Alloantibody - HLA Interactions in Human Serum
Schneider, M. M.; Scheidt, T.; Priddey, A. J.; Xu, C. K.; Hu, M.; Devenish, S. R. A.; Meisl, G.; Dobson, C. M.; Kosmoliaptsis, V.; Knowles, T. P. J.
10.1101/2020.09.14.296442 — biophysics — Posted on 2020-09-15
2250 Endophyte inoculation enhances Ulmus minor resistance to Dutch elm disease
Martinez-Arias, C.; Sobrino-Plata, J.; Ormeno-Moncalvillo, S.; Gil, L.; Rodriguez-Calcerrada, J.; Martin, J. A.
10.1101/2020.05.04.076349 — plant biology — Posted on 2020-09-15
2254 Nuclear organisation and replication timing are coupled through RIF1-PP1 interaction
Gnan, S.; Flyamer, I. M.; Klein, K. N.; Castelli, E.; Rapp, A.; Maiser, A.; Chen, N.; Weber, P.; Enervald, E.; Cardoso, C. M.; Bickmore, W. A.; Gilbert, D. M.; Buonomo, S.
10.1101/812156 — genomics — Posted on 2020-09-15
2255 Large-scale Phenomic and Genomic Analysis of Brain Asymmetrical Skew
Kong, X.; Postema, M. C.; Carrion Castillo, A.; Pepe, A.; Crivello, F.; Joliot, M.; Mazoyer, B.; Fisher, S. E.; Francks, C.
10.1101/756395 — neuroscience — Posted on 2020-09-15
2259 The mitochondrial surface receptor Tom70 protects the cytosol against mitoprotein-induced stress
Backes, S.; Bykov, Y. S.; Raeschle, M.; Zhou, J.; Lenhard, S.; Kraemer, L.; Muehlhaus, T.; Bibi, C.; Jann, C.; Smith, J. D.; Steinmetz, L. M.; Rapaport, D.; Storchova, Z.; Schuldiner, M.; Boos, F.; Herrmann, J. M.
10.1101/2020.09.14.296194 — cell biology — Posted on 2020-09-15
2260 Impact of sleep fragmentation, heart failure, and their combination, on the gut microbiome
Khannous-Lleiffe, O.; Willis, J. R.; Saus, E.; Cabrera-Aguilera, I.; Almendros, I.; Farre, R.; Gozal, D.; Farre, N.; Gabaldon, T.
10.1101/2020.09.11.294447 — microbiology — Posted on 2020-09-15
2262 SARS CoV-2 nucleocapsid protein forms condensates with viral genomic RNA
Jack, A.; Ferro, L. S.; Trnka, M. J.; Wehri, E.; Nadgir, A.; Costa, K.; Schaletzky, J.; Yildiz, A.
10.1101/2020.09.14.295824 — biophysics — Posted on 2020-09-14
2265 Impact of tumor-parenchyma biomechanics on liver metastatic progression: a multi-model approach
Wang, Y.; Brodin, E.; Nishii, K.; Frieboes, H. B.; Mumenthaler, S.; Sparks, J. L.; Macklin, P.
10.1101/2020.05.04.074989 — systems biology — Posted on 2020-09-14
2266 Phylogenomic reveals multiple introductions and early spread of SARS-CoV-2 into Peru
Juscamayta Lopez, E.; Tarazona, D.; Valdivia Guerrero, F.; Rojas Serrano, N.; Carhuaricra, D.; Maturrano Hernandez, L.; Gavilan Chavez, R.
10.1101/2020.09.14.296814 — genomics — Posted on 2020-09-14
2267 A home and rescue gene drive efficiently spreads and persists in populations
Kandul, N. P.; Liu, J.; Bennett, J. B.; Marshall, J. M.; Akbari, O.
10.1101/2020.08.21.261610 — genetics — Posted on 2020-09-14
2268 Strong effect of Penicillium roqueforti populations on volatile and metabolic compounds responsible for aromas, flavour and texture in blue cheeses
Caron, T.; Le Piver, M.; Peron, A.-C.; Lieben, P.; Lavigne, R.; Brunel, S.; Roueyre, D.; Place, M.; Bonnarme, P.; Giraud, T.; Branca, A.; Landaud, S.; Chassard, C.
10.1101/2020.03.02.974352 — evolutionary biology — Posted on 2020-09-14
2270 Methylotrophy, alkane-degradation, and pigment production as defining features of the globally distributed yet-uncultured phylum Binatota
Murphy, C. L.; Dunfield, P. E.; Sheremet, A.; Spear, J. R.; Stepanauskas, R.; Woyke, T.; Elshahed, M. S.; Youssef, N. H.
10.1101/2020.09.14.296780 — microbiology — Posted on 2020-09-14
2273 Leveraging non-structural data to predict structures of protein-ligand complexes
Paggi, J. M.; Belk, J. A.; Hollingsworth, S. A.; Villanueva, N.; Powers, A. S.; Clark, M. J.; Chemparathy, A. G.; Tynan, J. E.; Lau, T. K.; Sunahara, R. K.; Dror, R. O.
10.1101/2020.06.01.128181 — biophysics — Posted on 2020-09-14
2277 Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis
Lucilla, P.; Lasser, M.; Yusuff, T.; Jensen, M.; Ingraham, P.; Huber, E.; Singh, M. D.; Monahan, C.; Iyer, J.; Desai, I.; Karthikeyan, S.; Gould, D. J.; Yennawar, S.; Weiner, A. T.; Krishnan, A.; Rolls, M.; Lowery, L. A.; Girirajan, S.
10.1101/2020.09.14.295923 — genomics — Posted on 2020-09-14
2278 Pervasive selection pressure in wild and domestic pigs
Leno-Colorado, J.; Guirao-Rico, S.; Perez-Enciso, M.; Ramos-Onsins, S. E.
10.1101/2020.09.09.289439 — evolutionary biology — Posted on 2020-09-14
2280 Cohesin depleted cells rebuild functional nuclear compartments after endomitosis
Cremer, M.; Brandstetter, K.; Maiser, A.; Rao, S. S.; Schmid, V.; Guirao-Ortiz, M.; Mitra, N.; Mamberti, S.; Klein, K. N.; Gilbert, D. M.; Leonhardt, H.; Cardoso, M. C.; Lieberman Aiden, E.; Harz, H.; Cremer, T.
10.1101/816611 — cell biology — Posted on 2020-09-14
2282 Genetic structure and molecular diversity of Brazilian grapevine germplasm: management and use in breeding programs
de Oliveira, G. L.; de Souza, A. P.; de Oliveira, F. A.; Zucchi, M. I.; de Souza, L. M.; Moura, M. F.
10.1101/2020.05.05.078865 — molecular biology — Posted on 2020-09-14
2283 Promoter-proximal elongation regulates transcription in archaea
Blombach, F.; Fouqueau, T.; Matelska, D.; Smollett, K. L.; Werner, F.
10.1101/2020.09.14.296509 — molecular biology — Posted on 2020-09-14
2286 Anopheles albimanus natural microbiota is altered within one generation of laboratory colonization
Dada, N.; Benedict, A. C.; Lopez, F.; Lol, J. C.; Sheth, M.; Dzuris, N.; Padilla, N.; Lenhart, A.
10.1101/2020.06.02.129619 — microbiology — Posted on 2020-09-14
2290 A chemiluminescent protease probe for rapid, sensitive, and inexpensive detection of live Mycobacterium tuberculosis
Babin, B. M.; Fernandez-Cuervo, G.; Sheng, J.; Green, O.; Ordonez, A. A.; Turner, M. L.; Keller, L. J.; Jain, S. K.; Shabat, D.; Bogyo, M.
10.1101/2020.09.14.296772 — microbiology — Posted on 2020-09-14
2291 A rare variant in ANP32B impairs influenza virus replication in human cells
Staller, E.; Baillon, L.; Frise, R.; Peacock, T. P.; Sheppard, C. M.; Sancho-Shimizu, V.; Barclay, W. S.
10.1101/2020.04.06.027482 — microbiology — Posted on 2020-09-14
2292 Acute lymph node slices are a functional model system to study immunity ex vivo
Belanger, M. C.; Kinman, A. W. L.; Catterton, M. A.; Ball, A. G.; Groff, B. D.; Melchor, S. J.; Lukens, J. R.; Ross, A. E.; Pompano, R. R.
10.1101/865543 — immunology — Posted on 2020-09-14
2293 Flexible RSV prefusogenic fusion glycoprotein exposes multiple neutralizing epitopes that may collectively contribute to protective immunity
Natel, N.; Tian, J.-H.; Flores, R.; Jacobson, K.; Walker, M.; Portnoff, A.; Gueber-Xabier, M.; Massare, M. J.; Glenn, G.; Ellingsworth, L. R.; Smith, G.
10.1101/2020.09.14.296350 — immunology — Posted on 2020-09-14
2298 Syringeal vocal folds do not have a voice in zebra finch vocal development
Maxwell, A.; Adam, I.; Larsen, P. S.; Sorensen, P. G.; Elemans, C. P.
10.1101/2020.09.14.295931 — neuroscience — Posted on 2020-09-14
2299 Non-permissive SARS-CoV-2 infection of neural cells in the developing human brain and neurospheres
Pedrosa, C. d. S. G.; Goto-Silva, L.; Gomes, I. C.; Souza, L. R. Q.; Vitória, G.; Ornelas, I. M.; Karmirian, K.; Mendes, M. A.; Salerno, J. A.; Puig-Pijuan, T.; Veríssimo, C.; Temerozo, J. R.; Furtado, D. R.; Borges, H. L.; Souza, T. M. L.; Guimarães, M. Z. P.; Rehen, S.
10.1101/2020.09.11.293951 — neuroscience — Posted on 2020-09-14
2300 Constitutively enhanced genome integrity maintenance and direct stress mitigation characterize transcriptome of extreme stress-adapted Arabidopsis halleri
Lee, G.; Quintana, J.; Ahmadi, H.; Syllwasschy, L.; Janina, N.; Preite, V.; Anderson, J. E.; Pietzenuk, B.; Kraemer, U.
10.1101/859249 — plant biology — Posted on 2020-09-14
2302 Cell-extrinsic effects in T cell acute lymphoblastic pre-leukemia stem cells mediated by EphA3
Pliego Zamora, A. C.; Ranasinghe, H.; Lisle, J. E.; Huang, S.; Wadlow, R.; Scott, A. M.; Boyd, A. W.; Slape, C. I.
10.1101/2020.09.14.297127 — cancer biology — Posted on 2020-09-14
2305 A high-affinity calmodulin-binding site in the CyaA toxin translocation domain is essential for invasion into eukaryotic cells
Voegele, A.; Sadi, M.; O'Brien, D. P.; Gehan, P.; Raoux-Barbot, D.; Davi, M.; Hoss, S.; Brule, S.; Raynal, B.; Weber, P.; Mechaly, A.; Haouz, A.; Rodriguez, N.; Vachette, P.; Durand, D.; Brier, S.; Ladant, D.; Chenal, A.
10.1101/2020.09.14.296129 — biophysics — Posted on 2020-09-14
2310 Relative matching using low coverage sequencing
Petter, E.; Schweiger, R.; Shahino, B.; Shor, T.; Aker, M.; Almog, L.; Weissglas-Volkov, D.; Naveh, Y.; Navon, O.; Carmi, S.; Li, J. H.; Berisa, T.; Pickrell, J. K.; Erlich, Y.
10.1101/2020.09.09.289322 — bioinformatics — Posted on 2020-09-14
2317 Selective activation of FZD7 promotes mesendodermal differentiation of human pluripotent stem cells.
Gumber, D.; Do, M.; Suresh Kumar, N.; Wu, C. C. N.; Carson, D.; Gaasterland, T.; Willert, K.
10.1101/2020.09.14.297028 — developmental biology — Posted on 2020-09-14
2324 SpineS: An interactive time-series analysis software for dendritic spines
Argunsah, A. O.; Erdil, E.; Ghani, M. U.; Cortes, Y. R.; Hobbiss, A. F.; Karayannis, T.; Cetin, M.; Israely, I.; Unay, D.
10.1101/2020.09.12.294546 — neuroscience — Posted on 2020-09-14
2325 Wireless Ensembles of Sub-mm Microimplants Communicating as a Network near 1 GHz in a Neural Application
Lee, J.; Leung, V.; Lee, A.-H.; Huang, J.; Asbeck, P.; Mercier, P. P.; Shellhammer, S.; Larson, L.; Laiwalla, F.; Nurmikko, A.
10.1101/2020.09.11.293829 — neuroscience — Posted on 2020-09-14
2328 Podoplanin drives dedifferentiation and amoeboid invasion of melanoma
de Winde, C. M.; George, S. L.; Arp, A.; Benjamin, A. C.; Crosas-Molist, E.; Hari-Gupta, Y.; Carver, A.; Imperatore, V.; Martinez, V. G.; Sanz-Moreno, V.; Acton, S. E.
10.1101/2020.07.23.218578 — cancer biology — Posted on 2020-09-14
2329 Multi-modal Nonlinear Optical and Thermal Imaging Platform for Label-Free Characterization of Biological Tissue
Adams, W. R.; Mehl, B.; Lieser, E.; Wang, M.; Patton, S.; Throckmorton, G. A.; Jenkins, J. L.; Ford, J. B.; Gautam, R.; Brooker, J.; Jansen, E. D.; Mahadevan-Jansen, A.
10.1101/2020.04.06.023820 — biophysics — Posted on 2020-09-14
2331 Rapid Development of Improved Data-dependent Acquisition Strategies.
Davies, V.; Wandy, J.; Weidt, S.; van der Hooft, J. J. J.; Miller, A.; Daly, R.; Rogers, S.
10.1101/2020.09.11.293092 — bioinformatics — Posted on 2020-09-14
2332 Peripheral blood mononuclear cells preferentially activate 11-oxygenated androgens
Schiffer, L.; Bossey, A.; Taylor, A. E.; Akerman, I.; Scheel-Toellner, D.; Storbeck, K.-H.; Arlt, W.
10.1101/2020.09.08.288316 — biochemistry — Posted on 2020-09-14
2334 Long-read genome sequencing for the diagnosis of neurodevelopmental disorders
Hiatt, S. M.; Lawlor, J. M.; Handley, L. H.; Ramaker, R. C.; Rogers, B. B.; Partridge, E. C.; Boston, L. B.; Williams, M.; Jenkins, J.; Gray, D. E.; Holt, J. M.; Bowling, K. M.; Bebin, E. M.; Grimwood, J.; Schmutz, J.; Cooper, G. M.
10.1101/2020.07.02.185447 — genomics — Posted on 2020-09-14
2335 Identification of epigenome-wide DNA methylation differences between carriers of APOE ϵ4 and APOE ϵ2
Walker, R. M.; Vaher, K.; Bermingham, M. L.; Morris, S. W.; Bretherick, A. D.; Zeng, Y.; Rawlik, K.; Amador, C.; Campbell, A.; Haley, C. S.; Hayward, C.; Porteous, D. J.; McIntosh, A. M.; Marioni, R.; Evans, K. L.
10.1101/815035 — genetics — Posted on 2020-09-14
2337 Infectious disease phylodynamics with occurrence data
Featherstone, L.; Di Giallonardo, F.; Holmes, E. C.; Vaughan, T.; Duchene, S.
10.1101/596700 — evolutionary biology — Posted on 2020-09-14
2339 Observing changes in human functioning during induced sleep deficiency and recovery periods
Ochab, J. K.; Szwed, J.; Oles, K.; Beres, A.; Chialvo, D.; Domagalik, A.; Fafrowicz, M.; Gudowska-Nowak, E.; Marek, T.; Nowak, M. A.; Oginska, H.
10.1101/690313 — neuroscience — Posted on 2020-09-14
2340 Theta oscillations shift towards optimal frequency for cognitive control
Senoussi, M.; Verbeke, P.; Desender, K.; De Loof, E.; Talsma, D.; Verguts, T.
10.1101/2020.08.30.273706 — neuroscience — Posted on 2020-09-14
2341 Systemic inflammation causes microglial dysfunction with a mixed AD-like pathology.
Bathini, P.; Dupanloup, I.; Zenaro, E.; Terrabuio, E.; Ballabani, E.; Fischer, A.; Doucey, M.-A.; Alberi, L.
10.1101/2020.07.27.223198 — neuroscience — Posted on 2020-09-14
2345 SARS CoV-2 nucleocapsid protein forms condensates with viral genomic RNA
Jack, A.; Ferro, L. S.; Trnka, M. J.; Wehri, E.; Nadgir, A.; Costa, K.; Schaletzky, J.; Yildiz, A.
10.1101/2020.09.14.295824 — biophysics — Posted on 2020-09-14
2346 Evolution and Ecology in Widespread Acoustic Signaling Behavior Across Fishes
Rice, A. N.; Farina, S. C.; Makowski, A. J.; Kaataz, I. M.; Lobel, P. S.; Bemis, W. E.; Bass, A.
10.1101/2020.09.14.296335 — evolutionary biology — Posted on 2020-09-14
2348 Drivers of ESBL-producing Escherichia coli dynamics in calf fattening farms: a modelling study
Bastard, J.; Haenni, M.; Gay, E.; Glaser, P.; Madec, J.-Y.; Temime, L.; Opatowski, L.
10.1101/2020.09.14.296186 — microbiology — Posted on 2020-09-14
2352 Conservative route to extreme genome compaction in a miniature annelid
Martin-Duran, J. M.; Vellutini, B.; Marletaz, F.; Cetrangolo, V.; Cvetesic, N.; Thiel, D.; Henriet, S.; Grau-Bove, X.; Carrillo-Baltodano, A.; Gu, W.; Kerbl, A.; Marquez, Y.; Bekkouche, N.; Chourrout, D.; Gomez-Skarmeta, J.-L.; Irimia, M.; Lenhard, B.; Worsaae, K.; Hejnol, A.
10.1101/2020.05.07.078311 — genomics — Posted on 2020-09-14
2353 Minimal detection and low biological fluctuation of mitochondrial CpG methylation at the single-molecule level
Goldsmith, C. D.; Rodriguez-Aguilera, J. R.; El-Rifai, I.; Jarretier, A.; Hervieu, V.; Chagoya de Sanchez, V.; Dante, R.; Ichim, G.; Hernandez-Vargas, H.
10.1101/2020.09.14.296269 — genomics — Posted on 2020-09-14
2356 Peptide location fingerprinting reveals modification-associated biomarkers of ageing in human tissue proteomes
Ozols, M.; Eckersley, A.; Mellody, K. T.; Mallikarjun, V.; Warwood, S.; O'Cualain, R. M.; Knight, D.; Watson, R. E.; Griffiths, C. E.; Swift, J.; Sherratt, M. J.
10.1101/2020.09.14.296020 — molecular biology — Posted on 2020-09-14
2358 Transcriptional Feedback Disruption yield Escape-Resistant Antivirals
Chaturvedi, S.; Wolf, M.; Vardi, N.; Du, K.; Glazier, J.; Ke, R.; Chan, M.; Perelson, A.; Weinberger, L.
10.1101/464495 — microbiology — Posted on 2020-09-14
2360 Feeding recombinant Royalactin: Measures of improved lifespan and mitochondrial function in Caenorhabditis elegans
Li, X.; Ingram, T. L.; Wang, Y.; Derecka, K.; Courtier, N.; Piana, M.; Hardy, I. C. W.; Chakrabarti, l.; Stoger, R.
10.1101/2020.09.14.296053 — physiology — Posted on 2020-09-14
2361 Oncogenic KRAS engages an RSK1/NF1 complex in pancreatic cancer
Cheng, D. K.; Oni, T. E.; Park, Y.; Thalappillil, J. S.; Ting, H.-c.; Prasad, N.; Alagesan, B.; Rivera, K. D.; Pappin, D. J.; Van Aelst, L.; Tuveson, D. A.
10.1101/2020.09.14.295394 — cancer biology — Posted on 2020-09-14
2368 1RS.1BL molecular resolution provides novel contributions to wheat improvement
Ru, Z.; Juhasz, A.; Li, D.; Deng, P.; Zhao, J.; Gao, L.; Wang, K.; Keeble-Gagnere, G.; Yang, Z.; Li, G.; Wang, D.; Bose, U.; Colgrave, M.; Kong, C.; Zhao, G.; Zhang, X.; Liu, X.; Cui, G.; Wang, Y.; Niu, Z.; Wu, L.; Cui, D.; Jia, J.; Appels, R.; Kong, X.
10.1101/2020.09.14.295733 — genomics — Posted on 2020-09-14
2370 Automated detection of Hainan gibbon calls for passive acoustic monitoring
Dufourq, E.; Durbach, I.; Hansford, J. P.; Hoepfner, A.; Ma, H.; Bryant, J. V.; Stender, C. S.; Li, W.; Liu, Z.; Chen, Q.; Zhou, Z.; Turvey, S. T.
10.1101/2020.09.07.285502 — ecology — Posted on 2020-09-14
2371 Insect herbivory on urban trees: Complementary effects of tree neighbours and predation
Stemmelen, A.; Paquette, A.; Benot, M.-L.; Kadiri, Y.; Jactel, H.; Castagneyrol, B.
10.1101/2020.04.15.042317 — ecology — Posted on 2020-09-14
2372 The effect of E-liquid exposure on Caenorhabditis elegans.
Wang, Y.; Ingram, T. L.; Marshall, S.; Shephard, F.; Chakrabarti, L.
10.1101/2020.09.14.295790 — cell biology — Posted on 2020-09-14
2373 Towards a general model for predicting minimal metal concentrations co-selecting for antibiotic resistance plasmids
Arya, S.; Williams, A.; Vazquez Reina, S.; Knapp, C. W.; Kreft, J.-U.; Hobman, J. L.; Stekel, D. J.
10.1101/2020.09.14.295766 — microbiology — Posted on 2020-09-14
2378 FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation
Birsa, N.; Ule, A. M.; Garone, M. G.; Tsang, B.; Mattedi, F.; Chong, P. A.; Humphrey, J.; Jarvis, S.; Pisiren, M.; Wilkins, O. G.; Nosella, M.; Devoy, A.; Bodo, C.; De La Fuente, R.; Fisher, E. M.; Rosa, A.; Viero, G.; Forman-Kay, J. D.; Schiavo, G.; Fratta, P.
10.1101/2020.09.14.296038 — neuroscience — Posted on 2020-09-14
2379 The kallikrein-kinin system is falling into pieces: bradykinin fragments are biological active peptides
Souza-Silva, I. M.; de Paula, C. A.; Santos, A. K.; Oliveira, V. L. S.; Rocha, I. D.; Antunes, M.; Cordeiro, L. P. B.; Teixeira, V. P.; Scalzo, S.; Amaral, F. A.; Resende, J. M.; Fontes, M. A. P.; Menezes, G. B.; Guatimosim, S.; Santos, R.; Verano-Braga, T.
10.1101/2020.09.14.296004 — pharmacology and toxicology — Posted on 2020-09-14
2381 ASXL1 Directs Neutrophilic Differentiation via Modulation of MYC and RNA Polymerase II.
Braun, T. P.; Estabrook, J.; Coleman, D. J.; Schonrock, Z.; Smith, B. M.; Enright, T.; Coblentz, C.; Callahan, R.; Mohammed, H.; Druker, B. J.; Lusardi, T.; Maxson, J. E.
10.1101/2020.09.14.295295 — cancer biology — Posted on 2020-09-14
2382 The DNA Damage-Sensing NER Repair Factor XPC-RAD23B Does Not Recognize Bulky DNA Lesions with a Missing Nucleotide Opposite the Lesion.
Feher, K. M.; Kolbanovskiy, A.; Durandin, A.; Shim, Y.; Min, J. H.; Lee, Y. C.; Shafirovich, V.; Mu, H.; Broyde, S.; Geacintov, N. E.
10.1101/2020.09.14.293290 — biochemistry — Posted on 2020-09-14
2386 Deep learning for time series classification in ecology
Capinha, C.; Ceia-Hasse, A.; Kramer, A. M.; Meijer, C.
10.1101/2020.09.14.296251 — ecology — Posted on 2020-09-14
2387 Mapping of safe and early chemo-attenuated live Plasmodium falciparum immunization identifies immune signature of vaccine efficacy
Borrmann, S.; Sulyok, Z.; Mueller, K.; Sulyok, M.; Fendel, R.; Friesen, J.; Lalremruata, A.; Sandri, T. L.; Nguyen, T. T.; Calle, C. L.; Knoblich, A.; Ibanez, J.; Lorenz, F.-R.; Heimann, H. L.; Weller, D. M.; Steuder, R.; Adukpo, S.; Granados Bayon, P.; Molnar, Z.; Esen, M.; Metzger, W.; James, E. R.; Ruben, A.; Abebe, Y.; Chakravarty, S.; Manoj, A.; KC, N.; Murshedkar, T.; Hafalla, J. C.; Woldearegai, T. G.; O'Rourke, F.; Held, J.; Billingsley, P.; Sim, B. K. L.; Richie, T. L.; Kremsner, P.; Hoffman, S. L.; Matuschewski, K. L.; Mordmueller, B.
10.1101/2020.09.14.296152 — immunology — Posted on 2020-09-14
2389 SARS-CoV-2 Spike protein hijacks VEGF-A/Neuropilin-1 receptor signaling to induce analgesia
Moutal, A.; Martin, L. F.; Boinon, L.; Gomez, K.; Ran, D.; Zhou, Y.; Stratton, H. J.; Song, C.; Luo, S.; Gonzalez, K. B.; Perez-Miller, S.; Patwardhan, A.; Ibrahim, M.; Khanna, R.
10.1101/2020.07.17.209288 — neuroscience — Posted on 2020-09-14
2390 Syringeal vocal folds do not have a voice in zebra finch vocal development
Maxwell, A.; Adam, I.; Larsen, P. S.; Sorensen, P. G.; Elemans, C. P.
10.1101/2020.09.14.295931 — neuroscience — Posted on 2020-09-14
2391 Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors
Mavrommatis, L.; Jeong, H.-W.; Gomez-Giro, G.; Stehling, M.; Kienitz, M.-C.; Psathaki, O. E.; Bixel, G.; Morosan-Puopolo, G.; Gerovska, D.; Arauzo-Bravo, M. J.; Schwamborn, J. C.; Scholer, H. R.; Adams, R. H.; Vorgerd, M.; Brand-Saberi, B.; Zaehres, H.
10.1101/2020.09.14.295832 — bioengineering — Posted on 2020-09-14
2392 Simulations support the interaction of the SARS-CoV-2 spike protein with nicotinic acetylcholine receptors
Oliveira, A. S.; Ibarra, A. A.; Bermudez, I.; Casalino, L.; Gaieb, Z.; Shoemark, D. K.; Gallagher, T.; Sessions, R. B.; Amaro, R. E.; Mulholland, A. J.
10.1101/2020.07.16.206680 — biochemistry — Posted on 2020-09-14
2395 Brain Endothelial Cell TRPA1 Channels Initiate Neurovascular Coupling
Thakore, P.; Alvarado, M. G.; Ali, S.; Mughal, A.; Pires, P. W.; Yamasaki, E.; Pritchard, H. A. T.; Isakson, B. E.; Tran, C. H. T.; Earley, S.
10.1101/2020.09.14.295600 — neuroscience — Posted on 2020-09-14
2400 Suppression of amyloid-β secretion from neurons by cis-9, trans-11-octadecadienoic acid, an isomer of conjugated linoleic acid
Hata, S.; Kikuchi, K.; Kano, K.; Saito, H.; Sobu, Y.; Kinoshita, S.; Saito, T.; Saido, T. C.; Sano, Y.; Taru, H.; Aoki, J.; Komano, H.; Tomita, T.; Natori, S.; Suzuki, T.
10.1101/2020.09.13.295642 — biochemistry — Posted on 2020-09-14
2401 Tripartite holobiont system in a vent snail broadens the concept of chemosymbiosis
Yang, Y.; Sun, J.; Chen, C.; Zhou, Y.; Lan, Y.; Van Dover, C. L.; Wang, C.; Qiu, J.-W.; Qian, P.-Y.
10.1101/2020.09.13.295170 — ecology — Posted on 2020-09-14
2402 Reducing antimicrobial usage in small-scale chicken farms in Vietnam: A three-year intervention study
Phu, D. H.; Cuong, N. V.; Truong, B. D.; Kiet, B. T.; Hien, V. B.; Thu, H. T. V.; Yen, L. K.; Minh, N. T. T.; Padungtod, P.; Setyawan, E.; Thwaites, G.; Rushton, J.; Carrique-Mas, J.
10.1101/2020.09.13.295659 — microbiology — Posted on 2020-09-14
2407 The chaos in calibrating crop models
Wallach, D.; Palosuo, T.; Thorburn, P.; Hochman, Z.; Gourdain, E.; Andrianasolo, F.; Asseng, S.; Basso, B.; Buis, S.; Crout, N.; Dibari, C.; Dumont, B.; Ferrise, R.; Gaiser, T.; Garcia, C.; Gayler, S.; Ghahramani, A.; Hiremath, S.; Hoek, S.; Horan, H.; Hoogenboom, G.; Huang, M.; Jabloun, M.; Jansson, P.-E.; Jing, Q.; Justes, E.; Kersebaum, K. C.; Klosterhalfen, A.; Launay, M.; Lewan, E.; Luo, Q.; Maestrini, B.; Mielenz, H.; Moriondo, M.; Nariman Zadeh, H.; Padovan, G.; Olesen, J. E.; Poyda, A.; Priesack, E.; Pullens, J. W. M.; Qian, B.; Schuetze, N.; Shelia, V.; Souissi, A.; Specka, X.; Srivas
10.1101/2020.09.12.294744 — plant biology — Posted on 2020-09-14
2408 Subtype Heterogeneity and Epigenetic Convergence in Neuroendocrine Prostate Cancer
Cejas, P.; Xie, Y.; Font-Tello, A.; Lim, K.; Symala, S.; Qiu, X.; Tewari, A.; Shah, N.; Nguyen, H.; Patel, R.; Brown, L.; Coleman, I.; Hackeng, W. M.; Brosens, L.; Dreijerink, K.; Ellis, L.; Alaiwi, S. A.; Seo, J.-H.; Pomerantz, M.; Dall'Agnese, A.; Crowdis, J.; Van Allen, E.; Bellmunt, J.; Morrisey, C.; Nelson, P.; DeCaprio, J.; Farago, A.; Dyson, N.; Drapkin, B.; Liu, X. S.; Freedman, M.; Haffner, M.; Corey, E.; Brown, M.; Long, H. W.
10.1101/2020.09.13.291328 — cancer biology — Posted on 2020-09-14
2411 Rapid development of cloud-native intelligent data pipelines for scientific data streams using the HASTE Toolkit
Blamey, B.; Toor, S.; Dahlö, M.; Wieslander, H.; Harrison, P. J.; Sintorn, I.-M.; Sabirsh, A.; Wählby, C.; Spjuth, O.; Hellander, A.
10.1101/2020.09.13.274779 — bioinformatics — Posted on 2020-09-14
2415 High-resolution two-photon transcranial imaging of brain using direct wavefront sensing
Chen, C.; Qin, Z.; He, S.; Liu, S.; Lau, S.-F.; Wu, W.; Zhu, D.; Ip, N. Y.; Qu, J.
10.1101/2020.09.12.294421 — neuroscience — Posted on 2020-09-14
2417 A new model of decision processing in instrumental learning tasks
Miletic, S.; Boag, R. J.; Trutti, A. C.; Forstmann, B. U.; Heathcote, A.
10.1101/2020.09.12.294512 — neuroscience — Posted on 2020-09-14
2421 SpineS: An interactive time-series analysis software for dendritic spines
Argunsah, A. O.; Erdil, E.; Ghani, M. U.; Hobbiss, A. F.; Cortes, Y. R.; Cetin, M.; Israely, I.; Unay, D.; Karayannis, T.
10.1101/2020.09.12.294546 — neuroscience — Posted on 2020-09-14
2422 Subject identification using edge-centric functional connectivity
Jo, Y.; Faskowitz, J.; Zamani Esfahlani, F.; Sporns, O.; Betzel, R. F.
10.1101/2020.09.13.291898 — neuroscience — Posted on 2020-09-14
2425 Techno-economic assessment of animal cell-based meat
Risner, D.; Li, F.; Fell, J. S.; Pace, S.; Siegel, J. B.; Tagkopoulos, i.; Spang, E.
10.1101/2020.09.10.292144 — bioengineering — Posted on 2020-09-14
2429 Chronic Exposure to Glucocorticoids Induces Suboptimal Decision-Making in Mice
CABEZA, L.; RAMADAN, B.; GIUSTINIANI, J.; HOUDAYER, C.; PELLEQUER, Y.; GABRIEL, D.; FAUCONNET, S.; HAFFEN, E.; RISOLD, P.-Y.; FELLMANN, D.; BELIN, D.; PETERSCHMITT, Y. N.
10.1101/2020.09.11.293217 — neuroscience — Posted on 2020-09-14
2431 Pan-cancer analysis demonstrates that integrating polygenic risk scores with modifiable risk factors improves risk prediction
Kachuri, L.; Graff, R. E.; Smith-Byrne, K.; Meyers, T. J.; Rashkin, S. R.; Ziv, E.; Witte, J. S.; Johansson, M.
10.1101/2020.01.28.922088 — genetics — Posted on 2020-09-13
2433 A Motion Correction Strategy for Multi-Contrast based 3D parametric imaging: Application to Inhomogeneous Magnetization Transfer (ihMT)
Soustelle, L.; Lamy, J.; Le Troter, A.; Hertanu, A.; Guye, M.; Ranjeva, J.-P.; Varma, G.; Alsop, D. C.; Pelletier, J.; Girard, O.; Duhamel, G.
10.1101/2020.09.11.292649 — neuroscience — Posted on 2020-09-13
2434 Broad kinase inhibition mitigates early neuronal dysfunction and cognitive deficits in tauopathy
Koren, S. A.; Hamm, M. J.; Cloyd, R.; Fontaine, S. N.; Chishti, E.; Lanzillotta, C.; Rodriguez-Rivera, J.; Ingram, A.; Bell, M.; Galvis-Escobar, S.; Zulia, N.; Frolinger, T.; Di Domenico, F.; Duong, D.; Seyfried, N.; Powell, D. K.; Vandsburger, M.; Hartz, A. M. S.; Koren, J.; Axten, J. M.; Laping, N. J.; Abisambra, J. F.
10.1101/2020.07.31.229583 — neuroscience — Posted on 2020-09-13
2435 The new kid on the block: A dominant-negative mutation of phototropin1 enhances carotenoid content in tomato fruits
Kilambi, H. V.; Dindu, A.; Sharma, K.; Nizampatnam, N. R.; Gupta, N.; Thazath, N. P.; Dhanya, A. J.; Tyagi, K.; Sharma, S.; Kumar, S.; Sharma, R.; Sreelakshmi, Y.
10.1101/2020.09.13.295121 — plant biology — Posted on 2020-09-13
2438 Patient-Derived Mutant Forms of NFE2L2/NRF2 Drive Aggressive Murine Hepatoblastomas
Wang, H.; Lu, J.; Mandel, J. A.; Zhang, W.; Schwalbe, M.; Gorka, J.; Liu, Y.; Marburger, B.; Wang, J.; Ranganathan, S.; Prochownik, E. V.
10.1101/2020.09.13.295311 — cancer biology — Posted on 2020-09-13
2439 Glutamine deprivation triggers NAGK-dependent hexosamine salvage
Campbell, S. L.; Mesaros, C.; Affronti, H.; Tsang, T.; Noji, M.; Sun, K.; Izzo, L.; Trefely, S.; Kruijning, S.; Blair, I. A.; Wellen, K. E.
10.1101/2020.09.13.294116 — cancer biology — Posted on 2020-09-13
2440 Mpl is activated by dimers of MPN-linked calreticulin mutants stabilized by disulfide bonds and ionic interactions
Venkatesan, A.; Geng, J.; Kandarpa, M.; Wijeyesakere, S.; Bhide, A.; Talpaz, M.; Pogozheva, I. D.; Raghavan, M.
10.1101/2020.09.13.295485 — cancer biology — Posted on 2020-09-13
2441 Bacterial processing of glucose modulates C. elegans lifespan and healthspan
Kingsley, S. F.; Seo, Y.; Allen, C.; Ghanta, K. S.; Finkel, S. E.; Tissenbaum, H.
10.1101/2020.09.13.295451 — genetics — Posted on 2020-09-13
2443 High performance machine learning models can fully automate labeling of camera trap images for ecological analyses
Whytock, R. C.; Swiezewski, J.; Zwerts, J. A.; Bara-Słupski, T.; Koumba Pambo, A. F.; Rogala, M.; Bahaa-el-din, L.; Boekee, K.; Brittain, S.; Cardoso, A. W.; Henschel, P.; Lehmann, D.; Momboua, B.; Opepa, C. K.; Orbell, C.; Pitman, R. T.; Robinson, H. S.; Abernethy, K. A.
10.1101/2020.09.12.294538 — ecology — Posted on 2020-09-13
2446 DNA damage activates mTORC1 signaling in podocytes leading to glomerulosclerosis
Braun, F.; Blomberg, L.; Akbar-Hase, R. A.; Puelles, V.; Wong, M.; Rahmatollahi, M.; Fermin, D.; Slaats, G.; Koehler, S.; Brinkkoetter, P.; Lindenmeyer, M. T.; Cohen, C.; Kann, M.; Bloch, W.; Sampson, M. G.; Huber, T. B.; Schermer, B.; Benzing, T.; Schumacher, B.; Kurschat, C. E.
10.1101/2020.09.13.295303 — cell biology — Posted on 2020-09-13
2447 Wireless Ensembles of Sub-mm Microimplants Communicating as a Network near 1 GHz in a Neural Application
Lee, J.; Leung, V.; Lee, A.-H.; Huang, J.; Asbeck, P.; Mercier, P. P.; Shellhammer, S.; Larson, L.; Laiwalla, F.; Nurmikko, A.
10.1101/2020.09.11.293829 — neuroscience — Posted on 2020-09-13
2453 Chronic low-dose dioxin exposure accelerates high fat diet-induced hyperglycemia in female mice
Matteo, G.; Hoyeck, M. P.; Blair, H.; Zebarth, J.; Rick, K. R.; Williams, A.; Gagne, R.; Buick, J. K.; Yauk, C.; Bruin, J. E.
10.1101/2020.09.12.294587 — pharmacology and toxicology — Posted on 2020-09-13
2454 PSA-targeted Alpha-, Beta- and Positron Emitting Immuno-Theranostics in Murine Prostate Cancer Models and Non-Human Primates
Veach, D.; Storey, C. M.; Lueckerath, K.; Braun, K.; van Bodman, C.; Lamminmaeki, U.; Kalidindi, T.; Strand, S.-E.; Strand, J.; Altai, M.; Damoiseaux, R.; Zanzonico, P.; Benabdallah, N.; Pankov, D.; Scher, H. I.; Scardino, P.; Larson, S. M.; Lilja, H.; McDevitt, M. R.; Thorek, D. L.; Ulmert, D.
10.1101/2020.09.11.294264 — cancer biology — Posted on 2020-09-13
2456 Three-dimensional Printing of Customized Bioresorbable Airway Stents
Paunovic, N.; Bao, Y.; Coulter, F. B.; Masania, K.; Geks, A. K.; Klein, K.; Rafsanjani, A.; Cadalbert, J.; Kronen, P. W.; Kleger, N.; Karol, A.; Luo, Z.; Rüber, F.; Brambilla, D.; von Rechenberg, B.; Franzen, D.; Studart, A. R.; Leroux, J.-C.
10.1101/2020.09.12.294751 — bioengineering — Posted on 2020-09-13
2457 A saturating mutagenesis CRISPR-Cas9 mediated functional genomic screen identifies cis- and trans-regulatory elements of Oct4 in embryonic stem cells
Canver, M. C.; Tripathi, P.; Bullen, M. J.; Olshansky, M.; Kumar, Y.; Wong, L. H.; Turner, S. J.; Lessard, S.; Pinello, L.; Orkin, S. H.; Das, P. P.
10.1101/851683 — genomics — Posted on 2020-09-13
2460 Discovery of a Novel Inhibitor of Coronavirus 3CL Protease as a Clinical Candidate for the Potential Treatment of COVID-19
Boras, B.; Jones, R. M.; Anson, B. J.; Arenson, D.; Aschenbrenner, L.; Bakowski, M. A.; Beutler, N.; Binder, J.; Chen, E.; Eng, H.; Hammond, J.; Hoffman, R.; Kadar, E. P.; Kania, R.; Kimoto, E.; Kirkpatrick, M. G.; Lanyon, L.; Lendy, E. K.; Lillis, J. R.; Luthra, S. A.; Ma, C.; Noell, S.; Obach, R. S.; O'Brien, M. N.; O'Connor, R.; Ogilvie, K.; Owen, D.; Pettersson, M.; Reese, M. R.; Rogers, T.; Rossulek, M. I.; Sathish, J. G.; Steppan, C.; Ticehurst, M.; Updyke, L. W.; Zhu, Y.; Wang, J.; Chatterjee, A. K.; Mesecar, A. D.; Anderson, A. S.; Allerton, C.
10.1101/2020.09.12.293498 — pharmacology and toxicology — Posted on 2020-09-13
2461 Multi-modal pooled Perturb-CITE-Seq screens in patient models define novel mechanisms of cancer immune evasion
Frangieh, C. J.; Melms, J. C.; Thakore, P. I.; Geiger-Schuller, K. R.; Ho, P.; Luoma, A. M.; Cleary, B. R.; Malu, S.; Cuoco, M. S.; Zhao, M.; Rogava, M.; Hovey, L.; Rotem, A.; Bernatchez, C.; Wucherpfennig, K. W.; Johnson, B. E.; Rozenblatt-Rosen, O.; Schadendorf, D.; Regev, A.; Izar, B.
10.1101/2020.09.01.267211 — genomics — Posted on 2020-09-13
2464 Stable colony stimulating factor 1 fusion protein treatment increases HSC pool and enhances their mobilisation in mice.
Kaur, S.; Sehgal, A.; Wu, A. C.; Millard, S. M.; Batoon, L.; Ferrari-Cestari, M.; Levesque, J.-P.; Hume, D. A.; Raggatt, L. J.; Pettit, A. R.
10.1101/2020.09.13.292227 — cell biology — Posted on 2020-09-13
2465 The evolution of virulence in Pseudomonas aeruginosa during chronic wound infection
Vanderwoude, J.; Fleming, D.; Azimi, S.; Trivedi, U.; Rumbaugh, K. P.; Diggle, S. P.
10.1101/2020.05.29.124545 — microbiology — Posted on 2020-09-13
2467 A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing
Adams, S.; Purkiss, A. G.; Knowles, P. P.; Nans, A.; Briggs, D. C.; Borg, A.; Earl, C. P.; Goodman, K. M.; Nawrotek, A.; Borg, A. J.; McIntosh, P. B.; Houghton, F. M.; Kjaer, S.; McDonald, N. Q.
10.1101/2020.09.13.286047 — biophysics — Posted on 2020-09-13
2468 Enzymatic synthesis of fatty acid amides using microbial lipids as acyl group-donors and their biological activities
El-Baz, H. A.; Elazzazy, A. M.; Saleh, T. S.; Dritsas, P.; Mahyoub, J. A.; Baeshen, M. N.; Madian, H. R.; Alkhaled, M.; Aggelis, G.
10.1101/2020.09.13.295113 — biochemistry — Posted on 2020-09-13
2471 ATPase SRCAP is a new player in cell division, uncovering molecular aspects of Floating-Harbor syndrome
Messina, G.; Prozzillo, Y.; Delle Monache, F.; Santopietro, M. V.; Atterrato, M. T.; Dimitri, P.
10.1101/2020.09.12.294645 — cell biology — Posted on 2020-09-13
2473 Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders
Blokland, G. A.; Grove, J.; Chen, C.-Y.; Cotsapas, C.; Tobet, S.; Handa, R.; Schizophrenia Working Group of the Psychiatric Genomics Consortium, ; St Clair, D.; Lencz, T.; Mowry, B. J.; Periyasamy, S.; Cairns, M. J.; Tooney, P. A.; Wu, J. Q.; Kelly, B.; Kirov, G.; Sullivan, P. F.; Corvin, A.; Riley, B. P.; Esko, T.; Milani, L.; Jönsson, E. G.; Palotie, A.; Ehrenreich, H.; Begemann, M.; Steixner-Kumar, A.; Sham, P. C.; Iwata, N.; Weinberger, D. R.; Gejman, P. V.; Sanders, A. R.; Buxbaum, J. D.; Rujescu, D.; Giegling, I.; Konte, B.; Hartmann, A. M.; Bramon, E.; Murray, R. M.; Pato, M. T.; Lee,
10.1101/2020.08.13.249813 — genetics — Posted on 2020-09-13
2474 Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 disease severity
Inde, Z.; Yapp, C.; Joshi, G. N.; Spetz, J.; Fraser, C.; Deskin, B.; Ghelfi, E.; Sodhi, C.; Hackam, D.; Kobzik, L.; Croker, B.; Brownfield, D.; Jia, H.; Sarosiek, K. A.
10.1101/2020.09.13.276923 — cell biology — Posted on 2020-09-13
2475 Evaluation of stability and inactivation methods of SARS-CoV-2 in context of laboratory settings
Westhaus, S.; Widera, M.; Rabenau, H.; Hoehl, S.; Bojkova, D.; Cinatl, J.; Ciesek, S.
10.1101/2020.09.11.292581 — microbiology — Posted on 2020-09-13
2476 SARS-CoV-2 infection severity is linked to superior humoral immunity against the spike
Guthmiller, J. J.; Stovicek, O.; Wang, J.; Changrob, S.; Li, L.; Halfmann, P.; Zheng, N.-Y.; Utset, H.; Stamper, C. T.; Dugan, H. L.; Miller, W. D.; Huang, M.; Dai, Y.-N.; Nelson, C. A.; Hall, P. D.; Jansen, M.; Shanmugarajah, K.; Donington, J. S.; Krammer, F.; Fremont, D.; Joachimiak, A.; Kawaoka, Y.; Tesic, V.; Madariaga, M. L.; Wilson, P. C.
10.1101/2020.09.12.294066 — immunology — Posted on 2020-09-13
2477 Discovery of a Novel Inhibitor of Coronavirus 3CL Protease as a Clinical Candidate for the Potential Treatment of COVID-19
Boras, B.; Jones, R. M.; Anson, B. J.; Arenson, D.; Aschenbrenner, L.; Bakowski, M. A.; Beutler, N.; Binder, J.; Chen, E.; Eng, H.; Hammond, J.; Hoffman, R.; Kadar, E. P.; Kania, R.; Kimoto, E.; Kirkpatrick, M. G.; Lanyon, L.; Lendy, E. K.; Lillis, J. R.; Luthra, S. A.; Ma, C.; Noell, S.; Obach, R. S.; O'Brien, M. N.; O'Connor, R.; Ogilvie, K.; Owen, D.; Pettersson, M.; Reese, M. R.; Rogers, T.; Rossulek, M. I.; Sathish, J. G.; Steppan, C.; Ticehurst, M.; Updyke, L. W.; Zhu, Y.; Wang, J.; Chatterjee, A. K.; Mesecar, A. D.; Anderson, A. S.; Allerton, C.
10.1101/2020.09.12.293498 — pharmacology and toxicology — Posted on 2020-09-13
2479 Real-time conformational dynamics of SARS-CoV-2 spikes on virus particles
Lu, M.; Uchil, P. D.; Li, W.; Zheng, D.; Terry, D. S.; Gorman, J.; Shi, W.; Zhang, B.; Zhou, T.; Ding, S.; Gasser, R.; Prevost, J.; Beaudoin-Bussieres, G.; Anand, S. P.; Laumaea, A.; Grover, J. R.; Lihong, L.; Ho, D. D.; Mascola, J.; Finzi, A.; Kwong, P. D.; Blanchard, S. C.; Mothes, W.
10.1101/2020.09.10.286948 — microbiology — Posted on 2020-09-13
2480 Interaction network of SARS-CoV-2 with host receptome through spike protein
Gu, Y.; Cao, J.; Zhang, X.; Gao, H.; Wang, Y.; Wang, J.; Zhang, J.; Shen, G.; Jiang, X.; Yang, J.; Zheng, X.; Xu, J.; Zhang, C. C.; Lan, F.; Qu, D.; Zhao, Y.; Xu, G.; Xie, Y.; Luo, M.; Lu, Z.
10.1101/2020.09.09.287508 — microbiology — Posted on 2020-09-13
2484 A low-cost, open source, self-contained bacterial EVolutionary biorEactor (EVE)
Gopalakrishnan, V.; Krishnan, N. P.; McClure, E.; Pelesko, J.; Guo, D.; Card, K. J.; Williamson, D. F. K.; Webster, N.; Nichol, D.; Mandal, S.; Bonomo, R. A.; Scott, J. G.
10.1101/729434 — bioengineering — Posted on 2020-09-13
2486 RANKL from Bone Marrow Adipocytes Regulates Osteoclast Formation and Bone Loss in Mice
Zhi, X.; Hu, Y.; Li, X.; Cong, W.; Huang, B.; Chen, H.; Wang, Y.; Li, Y.; Wang, L.; Guo, J.; Liu, Y.; Cui, J.; Cao, L.; Weng, W.; Zhou, Q.; Chen, X.; Su, J.
10.1101/2020.09.12.294348 — cell biology — Posted on 2020-09-13
2487 Neuronal complexity is attenuated in chronic migraine and restored by HDAC6 inhibition
Bertels, Z.; Grewal, H.; Dripps, I.; Siegersma, K.; Laboy, A.; Witkowski, W.; Sheets, Z.; Shah, P.; Conway, C.; Petukhova, V.; Karumudi, B.; Petukhov, P. A.; Baca, S. M.; Rasenick, M. M.; Pradhan, A. A.
10.1101/2020.04.21.053272 — neuroscience — Posted on 2020-09-13
2489 Quantifying cytoskeletal heterogeneity via single-cell protein-complex fractionation
Vlassakis, J.; Hansen, L. L.; Higuchi-Sanabria, R.; Zhou, Y.; Tsui, C. K.; Dillin, A.; Huang, H.; Herr, A. E.
10.1101/2020.09.12.294801 — bioengineering — Posted on 2020-09-13
2492 Secondhand homes: Woodpecker cavity location and structure influences secondary nester's success.
Hardin, F. O.; Leivers, S.; Grace, J. K.; Cairns, D. M.; Campbell, T.; Pierce, B. L.; Morrison, M. L.
10.1101/2020.09.11.293860 — ecology — Posted on 2020-09-13
2497 Some theoretical aspects of reprogramming the standard genetic code
Nowak, K.; Blazej, P.; Wnetrzak, M.; Mackiewicz, D.; Mackiewicz, P.
10.1101/2020.09.12.294553 — synthetic biology — Posted on 2020-09-13
2498 TIN2 facilitates TRF1-mediated trans- and cis-interactions on physiologically relevant long telomeric DNA
Pan, H.; Kaur, P.; Liu, M.; Xu, P.; Mahn, C.; Barnes, R.; Tang, Q.; Hao, P.; Bhattaram, D.; You, C.; Piehler, J.; Weninger, K.; Riehn, R.; Smith, S.; Opersko, P. L.; Wang, H.
10.1101/2020.09.12.286559 — biophysics — Posted on 2020-09-13
2501 A Hybrid High-Resolution Anatomical MRI Atlas with Sub-parcellation of Cortical Gyri using Resting fMRI
Joshi, A. A.; Choi, S.; Chong, M.; Sonkar, G.; Gonzalez-Martinez, J.; Nair, D.; Wisnowski, J.; Haldar, J.; Shattuck, D.; Damasio, H.; Leahy, R. M.
10.1101/2020.09.12.294322 — bioinformatics — Posted on 2020-09-13
2502 Improved Prediction of Smoking Status via Isoform-Aware RNA-seq Deep Learning Models
Wang, Z.; Masoomi, A.; Xu, Z.; Boueiz, A.; Lee, S.; Zhao, T.; Cho, M.; Hersh, C. P.; Silverman, E. K.; Dy, J.; Castaldi, P.
10.1101/2020.09.09.290395 — genomics — Posted on 2020-09-13
2503 Quantitative and dynamic cell polarity tracking in plant cells
Gong, Y.; Varnau, R.; Wallner, E.-S.; Bergmann, D. C.; Cheung, L. S.
10.1101/2020.09.12.294942 — cell biology — Posted on 2020-09-13
2508 Designed PKC-targeting bryostatin analogs modulate innate immunity and neuroinflammation
Abramson, E.; Hardman, C.; Shimizu, A.; Hwang, S.; Hester, L. D.; Snyder, S. H.; Wender, P. A.; Kim, P. M.; Kornberg, M. D.
10.1101/2020.09.12.294918 — immunology — Posted on 2020-09-12
2510 Advanced Retinal Imaging and Ocular Parameters of the Rhesus Macaque Eye
Lin, K.; Tran, T.; Kim, S.; Park, S.; Stout, J. T.; Chen, R.; Rogers, J.; Yiu, G.; Thomasy, S.; Moshiri, A.
10.1101/2020.09.12.294165 — physiology — Posted on 2020-09-12
2511 Evolutionary Dynamics of Non-Coding Regions in Pancreatic Ductal Adenocarcinoma
Hayashi, A.; Ho, Y.-j.; Makohon-Moore, A. P.; Zucker, A.; Hong, J.; Reiter, J. G.; Huang, J.; Zhang, L.; Attiyeh, M. A.; Baez, P.; Kappagantula, R.; Melchor, J. P.; OReilly, E. M.; Socci, N. D.; Oki, S.; Lowe, S.; Iacobuzio-Donahue, C. A.
10.1101/2020.09.11.294389 — cancer biology — Posted on 2020-09-12
2514 Concerted evolution reveals co-adapted amino acid substitutions in Na+K+-ATPase of frogs that prey on toxic toads
Mohammadi, S.; Yang, L.; Harpak, A.; Herrera-Alvarez, S.; Rodriguez-Ordonez, M. d. P.; Peng, J.; Zhang, K.; Storz, J. F.; Dobler, S.; Crawford, A. J.; Andolfatto, P.
10.1101/2020.08.04.234435 — evolutionary biology — Posted on 2020-09-12
2515 The origin and maintenance of microbial symbionts in Drosophila larvae
Guilhot, R.; Lagmairi, A.; Olazcuaga, L.; Xuereb, A.; Fellous, S.
10.1101/2020.09.12.294868 — ecology — Posted on 2020-09-12
2516 Interspecies Chimeric Conditions Affect the Developmental Rate of Human Pluripotent Stem Cells
Brown, J.; Barry, C.; Schmitz, M.; Argus, C.; Bolin, J.; Schwartz, M.; Van Aartsen, A.; Steill, J.; Swanson, S.; Stewart, R.; Thomson, J.; Kendziorski, C.
10.1101/2020.09.12.293357 — developmental biology — Posted on 2020-09-12
2517 Ubc9 deletion in adipocytes causes lipoatrophy in mice
Cox, A. R.; Chernis, N.; Kim, K. H.; Masschelin, P. M.; Saha, P. K.; Briley, S. M.; Sharp, R.; Felix, J. B.; Moore, D. D.; Pangas, S. A.; Hartig, S. M.
10.1101/2020.09.12.294629 — developmental biology — Posted on 2020-09-12
2519 Gut metabolites influence susceptibility of neonatal mice to cryptosporidiosis.
VanDussen, K. L.; Funkhouser-Jones, L.; Akey, M. E.; Schaefer, D. A.; Ackerman, K.; Riggs, M. W.; Stappenbeck, T. S.; Sibley, L. D.
10.1101/2020.09.11.294462 — microbiology — Posted on 2020-09-12
2520 Combined protein and transcript single cell RNA sequencing reveals cardiovascular disease and HIV signatures
Vallejo, J.; Saigusa, R.; Gulati, R.; Ghosheh, Y.; Durant, C. P.; Roy, P.; Ehinger, E.; Pattarabanjird, T.; Padgett, L. E.; Olingy, C. E.; Hanna, D. B.; Landay, A. L.; Tracy, R. P.; Lazar, J. M.; Mack, W. J.; Weber, K. M.; Adimora, A. A.; Hodis, H. N.; Tien, P. C.; Ofotokun, I.; Heath, S. L.; Dinh, H. Q.; Shemesh, A.; McNamara, C. A.; Lanier, L. L.; Hedrick, C. C.; Kaplan, R. C.; Ley, K.
10.1101/2020.09.10.292086 — immunology — Posted on 2020-09-12
2521 Single-Cell Transcriptomic Attributes and Unbiased Computational Modeling for the Prediction of Immunomodulatory Potency of Mesenchymal Stromal Cells
Pradhan, P.; Chatterjee, P.; Stevens, H. Y.; Glen, C.; Medrano-Trochez, C.; Jimenez, A.; Kippner, L.; Seeto, W. J.; Li, Y.; Gibson, G.; Kurtzberg, J.; Kontanchek, T.; Yeago, C.; Roy, K.
10.1101/2020.09.12.294850 — immunology — Posted on 2020-09-12
2522 Integration of Biodynamic Imaging and RNA-seq predicts chemotherapy response in canine diffuse large B-cell lymphoma
Fine, J.; Dhawan, D.; Utturkar, S.; Chopra, G.; Utturkar, S.; Turek, J.; Nolte, D.; Childress, M. O.; Lanman, N. A.
10.1101/2020.09.11.290353 — cancer biology — Posted on 2020-09-12
2525 Disrupting upstream translation in mRNAs leads to loss-of function associated with human disease
Lee, D. S. M.; Park, J.; Kromer, A.; Regeneron Genetics Center, ; Rader, D. J.; Ritchie, M. D.; Ghanem, L. R.; Barash, Y.
10.1101/2020.09.09.287912 — genomics — Posted on 2020-09-12
2527 Deciphering the evolution of the transcriptional and regulatory landscape in human placenta
Sun, M.-a.; Wolf, G.; Wang, Y.; Ralls, S.; Senft, A.; Jin, J.; Dunn-Fletcher, C.; Muglia, L.; Macfarlan, T.
10.1101/2020.09.11.289686 — evolutionary biology — Posted on 2020-09-12
2530 RANKL from Bone Marrow Adipocytes Regulates Osteoclast Formation and Bone Loss in Mice
Su, J.; Zhi, X.; Hu, Y.; Li, X.; Cong, W.; Huang, B.; Chen, H.; Wang, Y.; Li, y.; Wang, L.; Guo, J.; Liu, Y.; Cui, J.; Cao, L.; weng, w.; Zhou, q.; Chen, X.
10.1101/2020.09.12.294348 — cell biology — Posted on 2020-09-12
2531 Galectin-1-deficient mice are protected against Trypanosoma cruzi infection through altered neutrophil migration and production of reactive oxygen species and nitric oxide
Riul, T. B.; Sales-Campos, H.; Lima-Junior, D. d. S.; Seixas Azzolini, A. E. C.; Cardoso, C. R. d. B.; Stowell, S. R.; Cummings, R. D.; Valim, Y. M. L.; Baruffi, M. D.
10.1101/2020.09.11.294199 — immunology — Posted on 2020-09-12
2534 CUB and Sushi Multiple Domains 1 (CSMD1) opposes the complement cascade in neural tissues
Baum, M. L.; Wilton, D. K.; Muthukumar, A.; Fox, R. G.; Carey, A.; Crotty, W.; Scott-Hewitt, N.; Bien, E.; Sabatini, D. A.; Lanser, T.; Frouin, A.; Gergits, F.; Havik, B.; Gialeli, C.; Nacu, E.; Blom, A. M.; Eggan, K.; Johnson, M. B.; McCarroll, S. A.; Stevens, B.
10.1101/2020.09.11.291427 — neuroscience — Posted on 2020-09-12
2536 Telomere-to-telomere assembly of the genome of an individual Oikopleura dioica from Okinawa using Nanopore-based sequencing
Bliznina, A.; Masunaga, A.; Mansfield, M. J.; Tan, Y.; Liu, A. W.; West, C.; Rustagi, T.; Chien, H.-C.; Kumar, S.; Pichon, J.; Plessy, C.; Luscombe, N. M.
10.1101/2020.09.11.292656 — genomics — Posted on 2020-09-12
2537 Bulk Segregant Approaches to Nutritional Genomics in Plasmodium falciparum
Kumar, S.; Li, X.; McDew-White, M.; Reyes, A.; Sayeed, A.; Haile, M.; Kennedy, S.; Carmago, N.; Checkley, L.; Vendrely, K.; Button-Simons, K.; Cheeseman, I.; Kappe, S.; Nosten, F.; Ferdig, M.; Vaughan, A.; Anderson, T.
10.1101/2020.09.12.294736 — genetics — Posted on 2020-09-12
2541 The KCNQ4-mediated M-current regulates the circadian rhythm in mesopontine cholinergic neurons
Tsogbadrakh, B.; Stupniki, S.; Kovacs, A.; Csemer, A.; Szentesi, P.; Pocsai, K.; Dionisio, L.; Spitzmaul, G.; Pal, B.
10.1101/2020.09.11.293423 — neuroscience — Posted on 2020-09-12
2544 Distinct mechanisms for TMPRSS2 expression explain organ-specific inhibition of SARS-CoV-2 infection by enzalutamide
Gao, D.; Li, F.; Han, M.; Dai, P.; Xu, W.; He, J.; Tao, X.; Wu, Y.; Tong, X.; Xia, X.; Guo, W.; Li, Y.; Zhu, Y.; Zhang, X.; Liu, Z.; Aji, R.; Cai, X.; Li, Y.; Qu, D.; Chen, Y.; Jiang, S.; Wang, Q.; Ji, H.; Xie, Y.; Sun, Y.; Lu, L.; Zhou, Y.
10.1101/2020.09.11.293035 — microbiology — Posted on 2020-09-12
2545 Immunologically distinct responses occur in the CNS of COVID-19 patients
Song, E.; Chow, R. D.; Jiang, R.; Zamecnik, C. R.; Loudermilk, R.; Dai, Y.; Liu, F.; Geng, B.; Chiarella, J.; Israelow, B.; Casanovas-Massana, A.; Ko, A.; Ring, A.; Kleinstein, S.; Spudich, S.; Wilson, M.; Iwasaki, A.; Farhadian, S. F.
10.1101/2020.09.11.293464 — immunology — Posted on 2020-09-12
2547 Ketogenesis restrains aging-induced exacerbation of COVID in a mouse model
Ryu, S.; Shchukina, I.; Youm, Y.-H.; Qing, H.; Hilliard, B. K.; Dlugos, T.; Zhang, X.; Yasumoto, Y.; Booth, C. J.; Fernandez-Hernando, C.; Suarez, Y.; Khanna, K. M.; Horvath, T.; Dietrich, M. O.; Artyomov, M.; Wang, A.; Dixit, V. D.
10.1101/2020.09.11.294363 — immunology — Posted on 2020-09-12
2548 Type I Interferon Limits Viral Dissemination-Driven Clinical Heterogeneity in a Native Murine Betacoronavirus Model of COVID-19
Qing, H.; Sharma, L.; Hilliard, B. K.; Peng, X.; Swaminathan, A.; Tian, J.; Israni-Winger, K.; Zhang, C.; Leao, D.; Ryu, S.; Habet, V.; Wang, L.; Tian, X.; Ishibe, S.; Young, L. H.; Kotenko, S.; Compton, S.; Booth, C. J.; Ring, A. M.; Dixit, V. D.; Wilen, C. B.; Pereira, J. P.; Dela Cruz, C. S.; Wang, A.
10.1101/2020.09.11.294231 — immunology — Posted on 2020-09-12
2549 SARS-CoV-2 infection of human iPSC-derived cardiac cells predicts novel cytopathic features in hearts of COVID-19 patients
Perez-Bermejo, J. A.; Kang, S. S.; Rockwood, S. J.; Simoneau, C. R.; Joy, D. A.; Ramadoss, G. N.; Silva, A. C.; Flanigan, W. R.; Li, H.; Nakamura, K.; Whitman, J. D.; Ott, M.; Conklin, B. R.; McDevitt, T. C.
10.1101/2020.08.25.265561 — cell biology — Posted on 2020-09-12
2550 Emergence of SARS-CoV-2 spike RBD mutants that enhance viral infectivity through increased human ACE2 receptor binding affinity
Ou, J.; Zhou, Z.; Dai, R.; Zhao, S.; Wu, X.; Zhang, J.; Lan, W.; Cui, L.; Wu, J.; Seto, D.; Chodosh, J.; Zhang, G.; Zhang, Q.
10.1101/2020.03.15.991844 — microbiology — Posted on 2020-09-12
2551 Evaluation of Safety and Immunogenicity of an Adjuvanted, TH-1 Skewed, Whole Virion Inactivated SARS-CoV-2 Vaccine - BBV152
Ganneru, B.; Jogdand, H.; Dharam, V. K.; Reddy, N.; Prasad, S. D.; Vellimudu, S.; Ella, K. M.; Ravikrishnan, R.; Awasthi, A.; Jose, J.; Rao, P.; Kumar, D.; Ella, R.; Abraham, P.; Yadav, P.; Sapkal, G. N.; Shete, A.; Desphande, G. R.; Mohandas, S.; Basu, A.; Gupta, N.; Mohan, K. V.
10.1101/2020.09.09.285445 — immunology — Posted on 2020-09-12
2552 Brain volumetric changes in the general population following the COVID-19 outbreak and lockdown
Salomon, T.; Cohen, A.; Ben-Zvi, G.; Gera, R.; Oren, S.; Roll, D.; Rozic, G.; Saliy, A.; Tik, N.; Tsarfati, G.; Tavor, I.; Schonberg, T.; Assaf, Y.
10.1101/2020.09.08.285007 — neuroscience — Posted on 2020-09-12
2554 Robust Tobacco Smoking Self-Report in two Cohorts of Vulnerable Pregnant Women and Adults
Saberi, S.; Smith, M.-S. R.; Ajaykumar, A.; Zhu, M.; Gadawski, I.; Sattha, B.; Maan, E. J.; Van Schalkwyk, J.; Elwood, C.; Boucoiran, I.; Money, D. M.; Cote, H. C.; CIHR Team in Cellular Aging and HIV Comorbidities in Women and Children (CARMA),
10.1101/2020.09.11.293902 — pathology — Posted on 2020-09-12
2555 Formation of polarized contractile interfaces by self-organized Toll-8/Cirl GPCR asymmetry
Lavalou, J.; Mao, Q.; Harmansa, S.; Kerridge, S.; Lellouch, A. C.; Philippe, J.-M.; Audebert, S.; Camoin, L.; Lecuit, T.
10.1101/2020.03.16.993758 — developmental biology — Posted on 2020-09-12
2558 A Pipeline for Precise and Efficient Genome Editing by sgRNA-Cas9 RNPs in Drosophila
Nyberg, K. G.; Nguyen, J. Q.; Kwon, Y.-J.; Blythe, S. A.; Beitel, G. J.; Carthew, R. W.
10.1101/2020.05.07.080762 — genetics — Posted on 2020-09-12
2559 Effects of land-use change and related pressures on alien and native subsets of island communities
Sanchez-Ortiz, K.; Taylor, K. J. M.; De Palma, A.; Essl, F.; Dawson, W.; Kreft, H.; Pergl, J.; Pysek, P.; van Kleunen, M.; Weigelt, P.; Purvis, A.
10.1101/2019.12.16.878041 — ecology — Posted on 2020-09-12
2561 Daytime variation in SARS-CoV-2 infection and cytokine production
Diallo, A. B.; Gay, L.; Coiffard, B.; Leone, M.; Mezouar, S.; Mege, J.-L.
10.1101/2020.09.09.290718 — immunology — Posted on 2020-09-12
2562 Regulation of Hippocampal Excitatory Synapses by the Zdhhc5 Palmitoyl Acyl Transferase
Shimell, J. J.; Globa, A. K.; Sepers, M. D.; Wild, A. R.; Matin, N.; Raymond, L. A.; Bamji, S. X.
10.1101/2020.09.11.294397 — neuroscience — Posted on 2020-09-12
2563 Assessing the relationship between cognitive empathy, age, and face perception using a sequential Bayesian analysis
Kist, J. D.; Bethlehem, R. A. I.; Stonier, B.; Sluijters, O. J. J.; Crockford, S. K.; de Jonge, E.; Freyberg, J.; Baron-Cohen, S.; Parsons, O. E.
10.1101/2020.09.11.292706 — neuroscience — Posted on 2020-09-12
2564 Correction of frameshift mutations in the atpB gene by translational recoding in chloroplasts of Oenothera and tobacco.
Malinova, I.; Zupok, A.; Massouh, A.; Schöttler, M. A.; Meyer, E. H.; Yaneva-Roder, L.; Szymanski, W.; Rössner, M.; Ruf, S.; Bock, R.; Greiner, S.
10.1101/2020.09.11.293548 — plant biology — Posted on 2020-09-12
2566 In vivo and in vitro mechanistic characterization of a clinically relevant PolγA mutation
Viscomi, C.; Pinheiro, P. F.; Pardo-Hernandez, C.; Reyes, A.; Tilokani, L.; Mishra, A.; Cerutti, R.; Li, S.; Ho, D. H.; Valenzuela, S.; Dogan, A. S.; Bradley, P.; Fernandez-Silva, P.; Trifunovic, A.; Prudent, J.; Minczuk, M.; Bindoff, L.; Macao, B.; Zeviani, M.; Falkenberg, M.
10.1101/2020.09.10.291369 — genetics — Posted on 2020-09-12
2567 Proteomics of autophagy deficient macrophages reveals enhanced antimicrobial immunity via the oxidative stress response
Maculins, T.; Verschueren, E.; Hinkle, T.; Chang, P.; Chalouni, C.; Lim, J.; Katakam, A. K.; Kunz, R. C.; Erickson, B. K.; Huang, T.; Choi, M.; Tsai, T.-H.; Vitek, O.; Reichelt, M.; Rohde, J. R.; Dikic, I.; Kirkpatrick, D. S.; Murthy, A.
10.1101/2020.09.10.291344 — cell biology — Posted on 2020-09-12
2568 Induction of AmpC-mediated-βlactam resistance requires a single lytic transglycosylase in Agrobacterium tumefaciens
Figueroa-Cuilan, W.; Howell, M.; Richards, C.; Randich, A.; Yadav, A. K.; Cava, F.; Brown, P. J. B.
10.1101/2020.09.10.292490 — microbiology — Posted on 2020-09-12
2569 Human IFITM3 restricts Chikungunya virus and Mayaro virus infection and is susceptible to virus-mediated counteraction
Franz, S.; Zillinger, T.; Pott, F.; Schüler, C.; Dapa, S.; Fischer, C.; Passos, V.; Stenzel, S.; Chen, F.; Döhner, K.; Hartmann, G.; Sodeik, B.; Pessler, F.; Simmons, G.; Drexler, J. F.; Goffinet, C.
10.1101/2020.09.11.292946 — microbiology — Posted on 2020-09-12
2571 NuMorph: tools for cellular phenotyping in tissue cleared whole brain images
Krupa, O.; Fragola, G.; Hadden-Ford, E.; Mory, J. T.; Liu, T.; Humphrey, Z.; Krishnamurthy, A.; Zylka, M. J.; Wu, G.; Stein, J. L.
10.1101/2020.09.11.293399 — neuroscience — Posted on 2020-09-12
2572 Constitutively active TrkB kinase signalling reduces actin filopodia dynamics and cell migration
Gupta, R.; Dittmeier, M.; Wohlleben, G.; Luzak, V.; Wegat, V.; Segebarth, D.; Bady, E.; Langlhofer, G.; Wachter, B.; Havlicek, S.; Lüningschrör, P.; Villmann, C.; Polat, B.; Monoranu, C. M.; Kuper, J.; Blum, R.
10.1101/2020.09.11.292565 — neuroscience — Posted on 2020-09-12
2574 Mild reductions in guard cell sucrose synthase 2 expression leads to slower stomatal opening and decreased whole plant transpiration in tobacco
Freire, F. B. S.; Bastos, R. L. G.; Bret, R. S. C.; Candido Sobrinho, S. A.; Medeiros, D. B.; Antunes, W. C.; Fernie, A. R.; Daloso, D. M.
10.1101/2020.09.11.293555 — plant biology — Posted on 2020-09-12
2575 Spatial analysis of ligand-receptor interactions in skin cancer at genome-wide and single-cell resolution
Tran, M.; Yoon, S.; Siok, M. T.; Andersen, S.; Devitt, K.; Lam, P.; Raghubar, A.; Purdue, B.; Hanson, S. J.; Jones, K.; Walters, S.; Tuong, Z. K.; Soyer, P. H.; Frazer, I. H.; Nguyen, Q.
10.1101/2020.09.10.290833 — cancer biology — Posted on 2020-09-12
2579 Cardiac Cell Type-Specific Gene Regulatory Programs and Disease Risk Association
Hocker, J. D.; Poirion, O. B.; Zhu, F.; Buchanan, J.; Zhang, K.; Chiou, J.; Wang, T.-M.; Hou, X.; Li, Y. E.; Zhang, Y.; Farah, E.; Wang, A.; McCulloch, A. D.; Gaulton, K. J.; Ren, B.; Chi, N. C.; Preissl, S.
10.1101/2020.09.11.291724 — genomics — Posted on 2020-09-12
2581 Reorganization of the neurobiology of language after sentence overlearning
Skipper, J. I.; Aliko, S.; Brown, S.; Jo, Y. J.; Lo, S.; Molimpakis, E.; Lametti, D. R.
10.1101/2020.09.11.293167 — neuroscience — Posted on 2020-09-12
2582 Phylogeny of docks and sorrels (Rumex, Polygonaceae) reveals plasticity of reproductive systems
Grant, K.; Koenemann, D.; Mansaray, J.; Ahmed, A.; Khamar, H.; El Oualidi, J.; Burke, J.
10.1101/2020.09.11.293118 — plant biology — Posted on 2020-09-12
2583 Diurnal Dynamics of the Arabidopsis Rosette Proteome and Phosphoproteome
Uhrig, R. G.; Eschevarria-Zomeno, S.; Schlaepfer, P.; Grossmann, J.; Roschitzki, B.; Korber, N.; Fiorani, F.; Gruissem, W.
10.1101/2020.09.11.293779 — plant biology — Posted on 2020-09-12
2584 NGPINT: A Next-generation protein-protein interaction software
Banerjee, S.; Velasquez-Zapata, V.; Fuerst, G.; Elmore, J. M.; Wise, R. P.
10.1101/2020.09.11.277483 — bioinformatics — Posted on 2020-09-12
2585 Rapid Development of Improved Data-dependent Acquisition Strategies.
Davies, V.; Wandy, J.; Weidt, S.; van der Hooft, J. J. J.; Miller, A.; Daly, R.; Rogers, S.
10.1101/2020.09.11.293092 — bioinformatics — Posted on 2020-09-12
2594 mTOR S-nitrosylation inhibits autophagy and lysosomal proteolysis
Tan, B. W. Q.; Tan, S.; Tan, B. W. L.; Navakkode, S.; Ng, C. Y.; Yuan, S.; Liang, M. C.; Liu, C.; Yin, S.; Chai, C.; Chew, K. C. M.; Tai, Y. K.; Sreedharan, S.; Lam, Y.; Liao, P.; Shen, H.-M.; Lim, K. L.; Wong, E.; Soong, T. W.
10.1101/2020.09.11.292607 — cell biology — Posted on 2020-09-11
2597 Control of feeding by Piezo-mediated gut mechanosensation in Drosophila
Min, S.; Oh, Y.; Verma, P.; Van Vactor, D.; Suh, G. S. B.; Liberles, S. D.
10.1101/2020.09.11.293712 — neuroscience — Posted on 2020-09-11
2598 A non-canonical EZH2 function sensitizes solid tumors to genotoxic stress
LIAO, Y.; Chen, C.-H.; Shah, N.; Xiao, T.; Feit, A.; Yang, M.; Cai, C.; Gao, S.; Xue, P.; Liu, Z.; Xu, H.; Lee, J.; Li, W.; Mei, S.; Pierre, R. S.; Shu, S.; Fei, T.; Duarte, M.; Zhao, J.; Bradner, J. E.; Polyak, K.; Kantoff, P. W.; Long, H.; Balk, S. W.; Liu, S. X.; Brown, M.; Xu, K.
10.1101/2020.09.11.291534 — cancer biology — Posted on 2020-09-11
2600 Long-read genome sequencing for the diagnosis of neurodevelopmental disorders
Hiatt, S. M.; Lawlor, J. M.; Handley, L. H.; Ramaker, R. C.; Rogers, B. B.; Partridge, E. C.; Boston, L. B.; Williams, M.; Jenkins, J.; Gray, D. E.; Holt, J. M.; Bowling, K. M.; Bebin, E. M.; Grimwood, J.; Schmutz, J.; Cooper, G. M.
10.1101/2020.07.02.185447 — genomics — Posted on 2020-09-11
2601 Causal role of L-glutamine in sickle cell disease painful crises: a Mendelian randomization analysis
Ilboudo, Y.; Garrett, M. E.; Bartolucci, P.; Brugnara, C.; Clish, C.; Hirschhorn, J.; Galacteros, F.; Ashley-Koch, A.; Telen, M.; Lettre, G.
10.1101/872358 — genetics — Posted on 2020-09-11
2602 Divergent DNA methylation signatures of X chromosome regulation in marsupials and eutherians
Singh, D.; Sun, D.; King, A. G.; Alquezar-Planas, D. E.; Johnson, R. N.; Alvarez-Ponce, D.; Yi, S. V.
10.1101/2020.08.26.269068 — evolutionary biology — Posted on 2020-09-11
2604 Modulation of cAMP metabolism for CFTR potentiation in human airway epithelial cells
Nguyen, J. P.; Bianca, M.; Huff, R. D.; Tiessen, N.; Inman, M. D.; Hirota, J. A.
10.1101/2020.09.11.294223 — cell biology — Posted on 2020-09-11
2605 NHR-49 acts in distinct tissues to promote longevity versus innate immunity
Naim, N.; Amrit, F. R.; Ratnappan, R.; DelBuono, N.; Loose, J. A.; Ghazi, A.
10.1101/2020.09.11.290452 — molecular biology — Posted on 2020-09-11
2607 Machine learning analysis of the bleomycin-mouse model reveals the spatial and temporal pulmonary inflammatory fingerprint
Bordag, N.; Biasin, V.; Schnoegl, D.; Valzano, F.; Jandl, K.; Nagy, B. M.; Sharma, N.; Wygrecka, M.; Kwapiszewska, G.; Marsh, L. M.
10.1101/2020.05.22.106690 — immunology — Posted on 2020-09-11
2608 Filaggrin deficient mice have a lower threshold for cutaneous allergen sensitization but do not develop spontaneous skin inflammation or atopy
Muhandes, L.; Pippel, M.; Chapsa, M.; Behrendt, R.; Ge, Y.; Dahl, A.; Yi, B.; Dalpke, A.; Winkler, S.; Hiller, M.; Beissert, S.; Jessberger, R.; Fallon, P. G.; Roers, A.
10.1101/2020.09.11.293688 — immunology — Posted on 2020-09-11
2609 Seasonal and long-term consequences of esca on grapevine stem xylem integrity
Bortolami, G.; Farolfi, E.; Badel, E.; Burlett, R.; Cochard, H.; Ferrer, N.; King, A.; Lamarque, L. J.; Lecomte, P.; Marchesseau Marchal, M.; Pouzoulet, J.; Torres-Ruiz, J. M.; Trueba, S.; Delzon, S.; Gambetta, G. A.; Delmas, C. E. L.
10.1101/2020.09.07.282582 — plant biology — Posted on 2020-09-11
2610 The methylome and comparative transcriptome after high intensity sprint exercise in human skeletal muscle
Maasar, M. F.; Turner, D. C.; Gorski, P. P.; Seaborne, R. A.; Strauss, J. A.; Shepherd, S. O.; Cocks, M.; Pillon, N. J.; Zierath, J. R.; Hulton, A. T.; Drust, B.; Sharples, A. P.
10.1101/2020.09.11.292805 — physiology — Posted on 2020-09-11
2611 Orphan G protein-coupled receptor, GPR37L1: pharmacological toolbox empty once again
Ngo, T.; Wilkins, B. P.; So, S. S.; Keov, P.; Chahal, K. K.; Finch, A. M.; Coleman, J. L. J.; Kufareva, I.; Smith, N. J.
10.1101/2020.09.11.290486 — pharmacology and toxicology — Posted on 2020-09-11
2617 Site-specific lipidation enhances IFITM3 membrane interactions and antiviral activity
Garst, E. H.; Lee, H.; Das, T.; Bhattacharya, S.; Percher, A.; Wiewiora, R.; Witte, I. P.; Li, Y.; Goger, M.; Peng, T.; Im, W.; Hang, H. C.
10.1101/2020.09.11.293324 — biochemistry — Posted on 2020-09-11
2623 Decellularization enables functional analysis of ECM remodeling in planarian regeneration
Sonpho, E.; Mann, F. G.; Levy, M.; Ross, E. J.; Guerrero-Hernandez, C.; Florens, L.; Saraf, A.; Doddihal, V.; Ounjai, P.; Sanchez Alvarado, A.
10.1101/2020.09.11.293936 — developmental biology — Posted on 2020-09-11
2624 A long-range chromatin interaction regulates SATB homeobox 1 gene expression in trophoblast stem cells
Yu, W.; Chakravarthi, V. P.; Borosha, S.; Ratri, A.; Dalal, K.; Wolfe, M. W.; Starks, R. R.; Tuteja, G.; Rumi, M. A. K.
10.1101/2020.09.11.294181 — developmental biology — Posted on 2020-09-11
2625 Cevipabulin-tubulin complex reveals a novel agent binding site on α-tubulin and provides insights into microtubule dynamic instability
Yang, J.; Yu, Y.; Li, Y.; Ye, H.; Yan, W.; Niu, L.; Zheng, Y.; Wang, Z.; Yang, Z.; Pei, H.; Wei, H.; Zhao, M.; Wen, J.; Yang, l.; Ouyang, L.; Wei, Y.; Chen, Q.; Li, W.; Chen, L.
10.1101/2020.09.11.293563 — cell biology — Posted on 2020-09-11
2627 Gut bacterial deamination of residual levodopa medication for Parkinson's disease
van Kessel, S. P.; de Jong, H. R.; Winkel, S. L.; van Leeuwen, S. S.; Nelemans, S. A.; Permentier, H.; Keshavarzian, A.; El Aidy, S.
10.1101/2020.02.13.945717 — microbiology — Posted on 2020-09-11
2628 Expression of varicella-zoster virus VLT-ORF63 fusion transcript induces broad viral gene expression during reactivation from neuronal latency
Ouwendijk, W. J. D.; Depledge, D. P.; Rajbhandari, L.; Rovis, T. R.; Jonjic, S.; Breuer, J.; Venkatesan, A.; Verjans, G. M. G. M.; Sadaoka, T.
10.1101/2020.09.11.294280 — microbiology — Posted on 2020-09-11
2630 Itk promotes the integration of TCR and CD28 costimulation, through its direct substrates, SLP-76 and Gads
Hallumi, E.; Shalah, R.; Lo, W.-L.; Corso, J.; Oz, I.; Beach, D.; Wittman, S.; Isenberg, A.; Sela, M.; Urlaub, H.; Weiss, A.; Yablonski, D.
10.1101/2020.09.11.293316 — immunology — Posted on 2020-09-11
2635 Systematically gap-filling the genome-scale metabolic model of CHO cells
Fouladiha, H.; Marashi, S.-A.; Li, S.; Li, Z.; Masson, H. O.; Vaziri, B.; Lewis, N. E.
10.1101/2020.01.27.921296 — systems biology — Posted on 2020-09-11
2638 Current challenges for epitope-agnostic TCR interaction prediction and a new perspective derived from image classification
Moris, P.; De Pauw, J.; Postovskaya, A.; Gielis, S.; De Neuter, N.; Bittremieux, W.; Ogunjimi, B.; Laukens, K.; Meysman, P.
10.1101/2019.12.18.880146 — bioinformatics — Posted on 2020-09-11
2639 GAMIBHEAR: whole-genome haplotype reconstruction from Genome Architecture Mapping data
Markowski, J.; Kempfer, R.; Kukalev, A.; Irastorza-Azcarate, I.; Loof, G.; Kehr, B.; Pombo, A.; Rahmann, S.; Schwarz, R. F.
10.1101/2020.01.30.927061 — bioinformatics — Posted on 2020-09-11
2640 Go Get Data (GGD): simple, reproducible access to scientific data
Cormier, M.; Belyeu, J.; Pedersen, B. S.; Brown, J.; Koster, J.; Quinlan, A.
10.1101/2020.09.10.291377 — bioinformatics — Posted on 2020-09-11
2643 Engineered expression of the invertebrate-specific scorpion toxin AaHIT reduces adult longevity and female fecundity in the diamondback moth Plutella xylostella
Harvey-Samuel, T.; Xu, X.; Lovett, E.; Dafa'alla, T.; Walker, A. S.; Norman, V. C.; Carter, R.; Teal, J.; Akilan, L.; Leftwich, P. T.; Alphey, L.
10.1101/2020.09.10.291187 — genetics — Posted on 2020-09-11
2648 Clostridioides difficile spore-entry into intestinal epithelial cells contributes to recurrence of the disease
Castro-Cordova, P.; Mora-Uribe, P.; Reyes-Ramirez, R.; Cofre-Araneda, G.; Orozco-Aguilar, J.; Brito-Silva, C.; Mendoza-Leon, M. J.; Kuehne, S.; Minton, N.; Pizarro-Guajardo, M.; Paredes-Sabja, D.
10.1101/2020.09.11.291104 — microbiology — Posted on 2020-09-11
2649 Effect of oxidized beta-carotene-oxygen copolymer compounds on health and performance of pre- and post-weaned pigs
Burton, G. W.; Van Kinh, L.; Riley, W. W.; Nickerson, J. G.; Vinh, D.; Van Phu, N.; Van, N. T.; Huyen, L. T. T.
10.1101/2020.08.07.241174 — immunology — Posted on 2020-09-11
2655 Cingulo-Opercular Control Network Supports Disused Motor Circuits in Standby Mode
Newbold, D. J.; Gordon, E. M.; Laumann, T. O.; Montez, D. F.; Seider, N. A.; Gross, S. J.; Zheng, A.; Nielsen, A. N.; Hoyt, C. R.; Hampton, J. M.; Ortega, M.; Adeyemo, B.; Miller, D. B.; Van, A. N.; Marek, S.; Schlaggar, B. L.; Carter, A. R.; Kay, B. P.; Greene, D. J.; Raichle, M. E.; Petersen, S. E.; Snyder, A. Z.; Dosenbach, N. U. F.
10.1101/2020.09.03.275479 — neuroscience — Posted on 2020-09-11
2657 Enteroendocrine cells sense bacterial tryptophan catabolites to activate enteric and vagal neuronal pathways
Ye, L.; Bae, M.; Cassilly, C. D.; Jabba, S. V.; Thorpe, D. W.; Martin, A. M.; Lu, H.-Y.; Wang, J.; Thompson, J. D.; Lickwar, C. R.; Poss, K. D.; Keating, D. J.; Jordt, S.-E.; Clardy, J.; Liddle, R. A.; Rawls, J. F.
10.1101/2020.06.09.142133 — physiology — Posted on 2020-09-11
2658 Disruption of the gut microbiota attenuates epithelial ovarian cancer sensitivity to cisplatin therapy
Chambers, L.; Esakov, E. L.; Braley, C.; Trestan, L.; Alali, Z.; Bayik, D.; Lathia, J.; Sangwan, N.; Bazeley, P.; Joehlin-Price, A. S.; Dwidar, M.; Hajjar, A.; Ahern, P. P.; Claesen, J.; Rose, P.; Vargas, R.; Michener, C.; Reizes, O.
10.1101/2020.06.16.155226 — cancer biology — Posted on 2020-09-11
2662 A COVID-19 antibody curbs SARS-CoV-2 nucleocapsid protein-induced complement hyper-activation
Kang, S.; Yang, M.; He, S.; Wang, Y.; Chen, X.; Chen, Y.; Hong, Z.; Liu, J.; Jiang, G.; Chen, Q.; Zhou, Z.; Zhou, Z.; Huang, Z.; Huang, X.; He, H.; Zheng, W.; Liao, H.-X.; Xiao, F.; Shan, H.; Chen, S.
10.1101/2020.09.10.292318 — molecular biology — Posted on 2020-09-11
2663 Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors
Hoffmann, H.- H.; Schneider, W. M.; Sanchez-Rivera, F. J.; Luna, J. M.; Ashbrook, A. W.; Soto-Feliciano, Y. M.; Leal, A. A.; Le Pen, J.; Ricardo-Lax, I.; Michailidis, E.; Hao, Y.; Stenzel, A. F.; Peace, A.; Allis, C. D.; Lowe, S. W.; MacDonald, M. R.; Poirier, J. T.; Rice, C. M.
10.1101/2020.09.11.291716 — microbiology — Posted on 2020-09-11
2665 A key linear epitope for a potent neutralizing antibody to SARS-CoV-2 S-RBD
Li, T.; Han, X.; Wang, Y.; Gu, C.; Wang, J.; Hu, C.; Li, S.; Wang, K.; Luo, F.; Huang, J.; Long, Y.; Song, S.; Wang, W.; Hu, J.; Wu, R.; Mu, S.; Hao, Y.; Chen, Q.; Gao, F.; Shen, M.; Long, S.; Gong, F.; Li, L.; Wu, Y.; Xu, W.; Cai, X.; Qu, D.; Yuan, Z.; Gao, Q.; Zhang, G.; He, C.; Nai, Y.; Deng, K.; Du, L.; Tang, N.; Xie, Y.; Huang, A.; Jin, A.
10.1101/2020.09.11.292631 — immunology — Posted on 2020-09-11
2667 Human trans-editing enzyme displays tRNA acceptor stem specificity and relaxed amino acid selectivity
Vargas-Rodriguez, O.; Bakhtina, M.; McGowan, D.; Abid, J.; Goto, Y.; Suga, H.; Musier-Forsyth, K.
10.1101/2020.09.11.293571 — biochemistry — Posted on 2020-09-11
2670 Unique and distinct identities and functions of leaf phloem cells revealed by single cell transcriptomics
Kim, J.-Y.; Symeonidi, E.; Pang, T. Y.; Denyer, T.; Weidauer, D.; Bezrutczyk, M.; Miras, M.; Zöllner, N.; Wudick, M. M.; Lercher, M.; Chen, L.-Q.; Timmermans, M. C. P.; Frommer, W. B.
10.1101/2020.09.11.292110 — plant biology — Posted on 2020-09-11
2672 KHz-rate volumetric voltage imaging of the whole zebrafish heart
Sacconi, L.; Silvestri, L.; Rodriguez, E.; Armstrong, G.; Pavone, F.; Shrier, A.; Bub, G.
10.1101/2020.07.13.196063 — physiology — Posted on 2020-09-11
2674 Modelling illustrates that genomic selection provides new opportunities for intercrop breeding
Bancic, J.; Werner, C.; Gaynor, C. R.; Gorjanc, G.; Odeny, D.; Ojulong, H.; Dawson, I. K.; Hoad, S.; Hickey, J. M.
10.1101/2020.09.11.292912 — genetics — Posted on 2020-09-11
2675 Phylogeographic model selection using convolutional neural networks
Masiero da Fonseca, E.; Rinaldi Colli, G.; de Pinho Werneck, F.; Carstens, B. C.
10.1101/2020.09.11.291856 — evolutionary biology — Posted on 2020-09-11
2676 Detection of sexually antagonistic transmission distortions in trio datasets
Lucotte, E. A.; Albinana, C. A.; Laurent, R.; Bherer, C.; Genome of the Netherland Consortium, ; Bataillon, T.; Toupance, B.
10.1101/2020.09.11.293191 — evolutionary biology — Posted on 2020-09-11
2682 Striatal BOLD and midfrontal theta power express motivation for action
Algermissen, J.; Swart, J. C.; Scheeringa, R.; Cools, R.; den Ouden, H. E. M.
10.1101/2020.09.11.292870 — neuroscience — Posted on 2020-09-11
2684 Metalloprotease Gp63 targeting novel glycoside exhibits potential antileishmanial activity
Chakrabarti, A.; Narayana, C.; Joshi, N.; Garg, S.; Garg, l.; Mishra, R. S.; Pati, S.; singh, s.
10.1101/2020.09.11.292920 — pharmacology and toxicology — Posted on 2020-09-11
2686 Post-fire vegetation succession in the Siberian subarctic tundra over 45 years
Heim, R. J.; Bucharova, A.; Brodt, L.; Kamp, J.; Rieker, D.; Soromotin, A. V.; Yurtaev, A.; Hoelzel, N.
10.1101/756163 — ecology — Posted on 2020-09-11
2687 LIONirs: flexible Matlab toolbox for fNIRS data analysis.
Tremblay, J.; Martinez-Montes, E.; Husser, A.; Caron-Desrochers, L.; Pouliot, P.; Vannasing, P.; Gallagher, A.
10.1101/2020.09.11.257634 — neuroscience — Posted on 2020-09-11
2688 Establishing a Living Biobank of Patient-Derived Organoids of Intraductal Papillary Mucinous Neoplasms of the Pancreas
Beato, F.; Reveron, D.; Dezsi, K. B.; Ortiz, A.; Johnson, J. O.; Chen, D.-T.; Ali, K.; Yoder, S. J.; Jeong, D.; Malafa, M.; Hodul, P.; Jiang, K.; Centeno, B. A.; Abdalah, M. A.; Balasi, J. A.; Tassielli, A. F.; Sarcar, B.; Teer, J. K.; DeNicola, G. M.; Permuth, J. B.; Fleming, J. B.
10.1101/2020.09.11.283168 — cancer biology — Posted on 2020-09-11
2691 Nicotinamide mononucleotide (NMN) de-amidation by the gut microbiome and evidence for indirect upregulation of the NAD+ metabolome
Kim, L.-J.; Chalmers, T. J.; Smith, G. C.; Das, A.; Poon, E. W. K.; Wang, J.; Tucker, S. P.; Sinclair, D. A.; Quek, L.-E.; Wu, L. E.
10.1101/2020.09.10.289561 — biochemistry — Posted on 2020-09-11
2693 Phosphodiesterase Type 4 anchoring regulates cAMP signaling to Popeye domain-containing proteins.
Baillie, G. S.; Tibbo, A.; Dobi, S.; McFall, A.; Tejeda, G. S.; Blair, C.; MacLeod, R.; MacQuaide, N.; Gok, C.; Fuller, W.; Smith, B.; Smith, G.; Brand, T.
10.1101/2020.09.10.290825 — biochemistry — Posted on 2020-09-11
2698 Epigenetic clock and methylation study of oocytes from a bovine model of reproductive aging
Kordowitzki, P.; Haghani, A.; Zoller, J. A.; Li, C. Z.; Raj, K.; Spangler, M. L.; Horvath, S.
10.1101/2020.09.10.290056 — developmental biology — Posted on 2020-09-11
2699 Decreased calmodulin recruitment triggers PMCA4 dysfunction and pancreatic injury in cystic fibrosis
Maleth, J.; Madacsy, T.; Varga, A.; Papp, N.; Deak, B.; Tel, B.; Pallagi, P.; Szabo, V.; Fanczal, J.; Rakonczay, Z.; Razga, Z.; Hohwieler, M.; Kleger, A.; Gray, M.; Hegyi, P.
10.1101/2020.09.10.290940 — cell biology — Posted on 2020-09-11
2703 Mutations in fbiD(Rv2983) as a novel determinant of resistance to pretomanid and delamanid in Mycobacterium tuberculosis
Rifat, D.; Li, S.-Y.; Ioerger, T. R.; Shah, K.; Lanoix, J.-P.; Lee, J.; Bashiri, G.; Sacchettini, J. C.; Nuermberger, E.
10.1101/2020.09.10.292508 — microbiology — Posted on 2020-09-11
2706 Chronically implantable LED arrays for behavioral optogenetics in primates.
Rajalingham, R.; Sorenson, M.; Azadi, R.; Bohn, S.; DiCarlo, J. J.; Afraz, A.
10.1101/2020.09.10.291583 — neuroscience — Posted on 2020-09-11
2708 A visual pathway for skylight polarization processing in Drosophila
Hardcastle, B. J.; Omoto, J. J.; Kandimalla, P.; Nguyen, B.-C. M.; Keles, M. F.; Boyd, N. K.; Hartenstein, V.; Frye, M. A.
10.1101/2020.09.10.291955 — neuroscience — Posted on 2020-09-11
2709 The Sez6 family inhibits complement at the level of the C3 convertase.
Qiu, W. Q.; Luo, S.; Ma, S. A.; Saminathan, P.; Li, H.; Gunnersen, J. M.; Gelbard, H. A.; Hammond, J. W.
10.1101/2020.09.11.292623 — neuroscience — Posted on 2020-09-11
2715 Parcellation of the human amygdala using recurrence quantification analysis
Bielski, K.; Adamus, S.; Kolada, E.; Raczaszek-Leonardi, J.; Szatkowska, I.
10.1101/2020.09.10.291351 — neuroscience — Posted on 2020-09-11
2719 Efficient cooperation of chloroplasts and mitochondria enhances ATP and sucrose production
Voon, C. P.; Law, Y.-S.; Guan, X.; Xu, Z.; Chu, W.-T.; Zhang, R.; Sun, F.; Labs, M.; Pribil, M.; Leister, D.; Hronkova, M.; Kubasek, J.; Cui, Y.; Jiang, L.; Tsuyama, M.; Gardestrom, P.; Tikkanen, M.; Lim, B. L.
10.1101/2020.09.09.289967 — plant biology — Posted on 2020-09-11
2720 Infrared thermography cannot be used to approximate core body temperature in wild primates
McFarland, R.; Barrett, L.; Fuller, A.; Hetem, R. S.; Porter, W. P.; Young, C.; Henzi, P.
10.1101/2020.09.10.289512 — physiology — Posted on 2020-09-11
2721 Myogenic Vasoconstriction Requires Canonical Gq/11 Signaling of Angiotensin II Type 1a Receptor in Murine Vasculature
Cui, Y.; Kassmann, M.; Nickel, S.; Zhang, C.; Alenina, N.; Anistan, Y. M.; Schleifenbaum, J.; Bader, M.; Welsh, D. G.; Huang, Y.; Gollasch, M.
10.1101/2020.09.09.289280 — physiology — Posted on 2020-09-11
2723 Structural and dynamic characterization of the C-terminal tail of ErbB2: disordered but not random
Pinet, L.; Wang, Y.; Deville, C.; Lescop, E.; Badache, A.; Bontems, F.; Morellet, N.; Durand, D.; Guerlesquin, F.; Assrir, N.; van Heijenoort, C.
10.1101/2020.09.09.290122 — biophysics — Posted on 2020-09-11
2725 Asthma-associated variants induce IL33 differential expression through a novel regulatory region
Aneas, I.; Decker, D. C.; Howard, C. L.; Sobreira, D. R.; Sakabe, N.; Blaine, K. M.; Stein, M. M.; Hrusch, C. L.; Montefiori, L. E.; Tena, J. J.; Magnaye, K. M.; Clay, S. M.; Gern, J. E.; Jackson, D. J.; Altman, M. C.; Naureckas, E. T.; Hogarth, D. K.; White, S. R.; Gomez-Skarmeta, J. L.; Schoetler, N.; Ober, C.; Sperling, A. I.; Nobrega, M. A.
10.1101/2020.09.09.290098 — genomics — Posted on 2020-09-11
2727 Specific induction of double negative B cells during protective and pathogenic immune responses
Ruschil, C.; Gabernet, G.; Lepennetier, G.; Heumos, S.; Kaminski, M.; Hrasko, Z.; Irmler, M.; Beckers, J.; Ziemann, U.; Nahnsen, S.; Owens, G. P.; Bennett, J. L.; Hemmer, B.; Kowarik, M. C.
10.1101/2020.09.08.285148 — immunology — Posted on 2020-09-11
2728 Antisense oligonucleotide therapy for SCN2A gain-of-function epilepsy
Li, M.; Jancovski, N.; Jafar-nejad, P.; Burbano, L.; Rollo, B.; Richards, K.; Drew, L.; Sedo, A.; pachernegg, S.; Soriano, A.; Jia, L.; Blackburn, T.; Roberts, B.; Nemiroff, A.; Dalby, K.; Maljevic, S.; Reid, C.; Rigo, F.; Petrou, S.
10.1101/2020.09.09.289900 — neuroscience — Posted on 2020-09-11
2729 Insulin potentiates the synchronous firing of arcuate nucleus Kiss1 neurons that protects against diet-induced obesity
Qiu, J.; Stincic, T. L.; Bosch, M. A.; Connors, A. M.; Petrie, S. K.; Ronnekleiv, O. K.; Kelly, M. J.
10.1101/2020.09.09.289017 — neuroscience — Posted on 2020-09-11
2730 Clinicopathologic Correlates and Natural History of Atypical Chronic Myeloid Leukemia
Montalban-Bravo, G.; Kanagal-Shamanna, R.; Sasaki, K.; Masarova, L.; Naqvi, K.; Jabbour, E.; DiNardo, C.; Takahashi, K.; Konopleva, M.; Pemmaraju, N.; Kadia, T. M.; Ravandi, F.; Daver, N. G.; Borthakur, G. M.; Estrov, Z. E.; Khoury, J. D.; Loghavi, S.; Soltysiak, K. A.; Pierce, S.; Bueso-Ramos, C.; Patel, K.; Verstovsek, S.; Kantarjian, H.; Bose, P.; Garcia-Manero, G.
10.1101/2020.09.10.291641 — cancer biology — Posted on 2020-09-11
2732 Freshwater Chlorobia exhibit metabolic specialization among cosmopolitan and endemic populations
Garcia, S. L.; Mehrshad, M.; Buck, M.; Tsuji, J. M.; Neufeld, J. D.; McMahon, K.; Bertilsson, S.; Greening, C.; Peura, S.
10.1101/2020.09.10.291559 — ecology — Posted on 2020-09-11
2733 Cellular mechanisms of chick limb bud morphogenesis
Lesnicar-Pucko, G.; Belmonte, J. M.; Musy, M.; Glazier, J. A.; Sharpe, J. A.
10.1101/2020.09.10.292359 — developmental biology — Posted on 2020-09-11
2734 The phosphatase inhibitor LB-100 acts synergistically with the NPR2 agonist BMN-111 to improve bone growth
Shuhaibar, L. C.; Kaci, N.; Egbert, J. R.; Loisay, L.; Vigone, G.; Uliasz, T. F.; Dambroise, E.; Swingle, M. R.; Honkanen, R. E.; Jaffe, L. A.; Legeai-Mallet, L.
10.1101/2020.09.10.288589 — developmental biology — Posted on 2020-09-11
2736 Parvalbumin interneurons in the nucleus accumbens regulate impairment of risk avoidance in DISC1 transgenic mice
Zhou, X.; Wu, B.; Xiao, Q.; He, W.; Zhou, Y.; Wei, P.; Zhang, X.; Liu, Y.; Wang, J.; Li, W.; Wang, L.; Tu, J.
10.1101/2020.09.10.291450 — neuroscience — Posted on 2020-09-11
2737 Quantitative analysis of tyrosine phosphorylation from FFPE tissues reveals patient specific signaling networks
Kohale, I. N.; Burgenske, D. M.; Mladek, A. C.; Bakken, K. K.; Kuang, J.; Boughey, J. C.; Wang, L.; Carter, J. M.; Haura, E. B.; Goetz, M. P.; Sarkaria, J. N.; White, F.
10.1101/2020.09.10.291922 — systems biology — Posted on 2020-09-11
2740 FRC-QE: A robust and comparable 3D microscopy image quality metric for cleared organoids
Preusser, F.; dos Santos, N.; Contzen, J.; Stachelscheid, H.; Costa, E. T.; Mergenthaler, P.; Preibisch, S.
10.1101/2020.09.10.291286 — bioinformatics — Posted on 2020-09-11
2741 R2DT: computational framework for template-based RNA secondary structure visualisation across non-coding RNA types
Sweeney, B. A.; Hoksza, D.; Nawrocki, E. P.; Ribas, C. E.; Madeira, F.; Cannone, J. J.; Gutell, R. R.; Maddala, A.; Meade, C.; Williams, L. D.; Petrov, A. S.; Chan, P. P.; Lowe, T. M.; Finn, R. D.; Petrov, A. I.
10.1101/2020.09.10.290924 — bioinformatics — Posted on 2020-09-11
2750 Anti-NS1 antibodies induced by immunization with dendritic cell targeted hybrid monoclonal antibodies do not induce platelet dysfunction.
Vicentin, E. C. M.; Amorim, K. N. d. S.; Yamamoto, M. M.; Souza, H. F. d. S.; Rosa, D. S.; Goncalves, A. J. d. S.; Alves, A. M. d. B.; Boscardin, S. B.
10.1101/2020.09.10.292334 — immunology — Posted on 2020-09-11
2752 A simple permutation-based test of intermodal correspondence
Weinstein, S. M.; Vandekar, S. N.; Adebimpe, A.; Tapera, T. M.; Robert-Fitzgerald, T.; Gur, R. C.; Gur, R. E.; Raznahan, A.; Satterthwaite, T. D.; Alexander-Bloch, A. F.; Shinohara, R. T.
10.1101/2020.09.10.285049 — neuroscience — Posted on 2020-09-11
2754 Scribble controls social behaviors through the regulation of the ERK/Mnk1 pathway
MOREAU, M. M.; Pietropaolo, S.; Ezan, J.; Robert, B. J. A.; Miraux, S.; Maitre, M.; Cho, Y.; Crusio, W. E.; Montcouquiol, M.; Sans, N.
10.1101/2020.09.10.289397 — neuroscience — Posted on 2020-09-11
2755 Coordination of two enhancers drives expression of olfactory trace amine-associated receptors
Fei, A.; Wu, W.; Tan, L.; Tang, C.; Xu, Z.; Huo, X.; Bao, H.; Johnson, M.; Hartmann, G.; Talay, M.; Yang, C.; Riegler, C.; Joseph, K.; Engert, F.; Xie, S.; Barnea, G.; Liberles, S.; Yang, H.; Li, Q.
10.1101/2020.09.10.288951 — neuroscience — Posted on 2020-09-11
2758 FLCN Gene Ablation Reduces Fibrosis and Inflammation in a Diet-Induced NASH Model
Paquette, M.; Yan, M.; El-Houjeiri, L.; Biondini, M.; Ramirez-Reyes, J. M. J.; Pacis, A.; Jeong, H.; Estall, J. L.; Siegel, P. M.; Pause, A.
10.1101/2020.09.10.291617 — pathology — Posted on 2020-09-11
2762 Mechanistic basis for motor-driven membrane constriction by dynamin
Ganichkin, O.; Vancraenenbroeck, R.; Rosenblum, G.; Hofmann, H.; Mikhailov, A. S.; Daumke, O.; Noel, J. K.
10.1101/2020.09.10.289546 — biophysics — Posted on 2020-09-11
2763 Go Get Data (GGD): simple, reproducible access to scientific data
Quinlan, A.; Cormier, M.; Belyeu, J.; Pedersen, B. S.; Brown, J.; Koster, J.
10.1101/2020.09.10.291377 — bioinformatics — Posted on 2020-09-11
2766 DyNeuMo Mk-1: A Fully-Implantable, Motion-Adaptive Neurostimulator with Configurable Response Algorithms
Zamora, M.; Toth, R.; Ottaway, J.; Gillbe, T.; Martin, S.; Benjaber, M.; Lamb, G.; Noone, T.; Nairac, Z.; Constandinou, T. G.; Herron, J.; Gillbe, I.; De Wachter, S.; Knowles, C. H.; Aziz, T. Z.; Green, A. L.; Denison, T.
10.1101/2020.09.10.292284 — bioengineering — Posted on 2020-09-11
2768 Population-based Carrier Screening and Prenatal Diagnosis of Fragile X Syndrome in East Asian Populations
Guo, Q.; Chang, Y.-Y.; Huang, C.-H.; Hsiao, Y.-S.; Hsiao, Y.-C.; Chiu, I.-f.; Zhou, Y.; Zhang, H.; Ko, T.-M.
10.1101/2020.09.10.292219 — genetics — Posted on 2020-09-11
2769 Engineered expression of the invertebrate-specific scorpion toxin AaHIT reduces adult longevity and female fecundity in the diamondback moth Plutella xylostella
Harvey-Samuel, T.; Xu, X.; Lovett, E.; Dafa'alla, T.; Walker, A. S.; Norman, V. C.; Carter, R.; Teal, J.; Akilan, L.; Leftwich, P. T.; Alphey, L.
10.1101/2020.09.10.291187 — genetics — Posted on 2020-09-11
2770 CycleFlow quantifies cell-cycle heterogeneity in vivo
Jolly, A.; Fanti, A.-K.; Grässer, I.; Becker, N. B.; Höfer, T.
10.1101/2020.09.10.291088 — cell biology — Posted on 2020-09-11
2772 Self-assembly of progenitor cells under the aegis of platelet factors facilitates human skin organoid formation and vascularized wound healing
Peking, P.; Krisch, L.; Wolf, M.; Hoog, A.; Vari, B.; Poupardin, R.; Scharler, C.; Russe, L.; Stachelscheid, H.; Schneeberger, A.; Schallmoser, K.; STRUNK, D.
10.1101/2020.09.10.292409 — cell biology — Posted on 2020-09-11
2773 Single-Cell RNAseq of Out-of-Thaw Mesenchymal Stromal Cells Shows Striking Tissue-of-Origin Differences and Inter-donor Cell-Cycle Variations
Trochez, C. M.; Chatterjee, P.; Pradhan, P.; Ogle, M. E.; Botchwey, E. A.; Kurtzberg, J.; Yeago, C.; Gibson, G.; Roy, K.
10.1101/2020.09.10.290155 — cell biology — Posted on 2020-09-11
2774 Ribosome stalling caused by the Argonaute-miRNA-SGS3 complex regulates production of secondary siRNA biogenesis in plants
Iwakawa, H.-o.; Lam, A. Y. W.; Mine, A.; Fujita, T.; Kiyokawa, K.; Yoshikawa, M.; Takeda, A.; Iwasaki, S.; Tomari, Y.
10.1101/2020.09.10.288902 — molecular biology — Posted on 2020-09-11
2775 Brain Connectivity Patterns in Children Linked to Neurocognitive Abilities
Sripada, C.; Angstad, M.; Rutherford, S.; Taxali, A.; Clark, D. A.; Greathouse, T.; Weigard, A.; Hyde, L.; Heitzeg, M.
10.1101/2020.09.10.291500 — neuroscience — Posted on 2020-09-11
2776 Network and systems based re-engineering of dendritic cells with non-coding RNAs forcancer immunotherapy
Lai, X.; Dreyer, F. S.; Cantone, M.; Eberhardt, M.; Gerer, K. F.; Jaitly, T.; Uebe, S.; Lischer, C.; Ekici, A. B.; Wittmann, J.; Jaeck, H.-M.; Schaft, N.; Doerrie, J.; Vera, J.
10.1101/2020.09.10.287847 — systems biology — Posted on 2020-09-11
2777 Reef Cover: a coral reef classification for global habitat mapping from biophysical remote sensing.
Kennedy, E. V.; Roelfsema, C.; Lyons, M.; Kovacs, E.; Borrego-Acevedo, R.; Roe, M.; Phinn, S.; Larsen, K.; Murray, N.; Yuwono, D.; Wolff, J.; Tudman, P.
10.1101/2020.09.10.292243 — systems biology — Posted on 2020-09-11
2780 Proteome-wide prediction of bacterial carbohydrate-binding proteins as a tool for understanding commensal and pathogen colonisation of the vaginal microbiome
Bonnardel, F.; Haslam, S. M.; Dell, A.; Feizi, T.; Liu, Y.; Tajadura-Ortega, V.; Akune, Y.; Sykes, L.; Bennett, P. R.; MacIntyre, D. A.; Lisacek, F.; Imberty, A.
10.1101/2020.09.10.291781 — bioinformatics — Posted on 2020-09-11
2781 Many bat species are not potential hosts of SARS-CoV and SARS-CoV-2: Evidence from ACE2 receptor usage
Yan, H.; Jiao, H.; Liu, Q.; Zhang, Z.; Wang, X.; Guo, M.; Wang, B.-J.; Lan, K.; Chen, Y.; Zhao, H.
10.1101/2020.09.08.284737 — ecology — Posted on 2020-09-10
2782 Inflammation potentiates JMML-like blood defects in Shp2 mutant Noonan syndrome
Solman, M.; Blokzijl-Franke, S.; Yan, C.; Yang, Q.; Kamel, S. M.; Bakkers, J.; Langenau, D. M.; den Hertog, J.
10.1101/2020.09.10.289090 — developmental biology — Posted on 2020-09-10
2783 Peripheral microtubules ensure asymmetric furrow positioning in neural stem cells
Thomas, A.; Gallaud, E.; Pascal, A.; Serre, L.; Arnal, I.; Richard-Parpaillon, L.; Savoian, M. S.; GIET, R.
10.1101/2020.09.10.291112 — cell biology — Posted on 2020-09-11
2784 Real-time conformational dynamics of SARS-CoV-2 spikes on virus particles
Lu, M.; Uchil, P. D.; Li, W.; Zheng, D.; Terry, D. S.; Gorman, J.; Shi, W.; Zhang, B.; Zhou, T.; Ding, S.; Gasser, R.; Prevost, J.; Beaudoin-Bussieres, G.; Anand, S. P.; Laumaea, A.; Grover, J. R.; Lihong, L.; Ho, D. D.; Mascola, J.; Finzi, A.; Kwong, P. D.; Blanchard, S. C.; Mothes, W.
10.1101/2020.09.10.286948 — microbiology — Posted on 2020-09-10
2785 HetF protein is a new divisome component in a filamentous and developmental cyanobacterium
Xing, W.-Y.; Liu, J.; Wang, Z.-Q.; Zhang, J.-Y.; Zeng, X.; Yang, Y.; Zhang, C.-C.
10.1101/2020.09.09.290692 — microbiology — Posted on 2020-09-10
2786 Structure of the Human Secretory Immunoglobulin M Core
Kumar, N.; Arthur, C. P.; Ciferri, C.; Matsumoto, M. L.
10.1101/2020.09.10.291138 — immunology — Posted on 2020-09-11
2789 Neural vulnerability and hurricane-related media predict posttraumatic stress in youth
Dick, A. S.; Silva, K.; Gonzalez, R.; Sutherland, M. T.; Laird, A. R.; Thompson, W. K.; Tapert, S. F.; Squeglia, L. M.; Gray, K. M.; Nixon, S. J.; Cottler, L. B.; La Greca, A. M.; Gurwitch, R. H.; Comer, J. S.
10.1101/2020.08.27.271056 — neuroscience — Posted on 2020-09-10
2791 Spatial analysis of ligand-receptor interactions in skin cancer at genome-wide and single-cell resolution
Tran, M.; Yoon, S.; Andersen, S.; Devitt, K.; Lam, P.; Raghubar, A.; Purdue, B.; Hanson, S. J.; Jones, K.; Walters, S.; Tuong, Z. K.; Soyer, P. H.; Frazer, I. H.; Nguyen, Q.
10.1101/2020.09.10.290833 — cancer biology — Posted on 2020-09-10
2792 Identifying protein subcellular localisation in scientific literature using bidirectional deep recurrent neural network
David, R.; Menezes, R.-J. D.; Klerk, J. D.; Castleden, I. R.; Hooper, C. M.; Carneiro, G.; Gilliham, M.
10.1101/2020.09.09.290577 — bioinformatics — Posted on 2020-09-10
2793 The inhibitory activity of GlyT2 targeting bioactive lipid analgesics are influenced by formation of a deep lipid cavity
Wilson, K. A.; Mostyn, S. N.; Frangos, Z. J.; Shimmon, S.; Rawling, T.; Vandenberg, R. J.; O'Mara, M. L.
10.1101/2020.09.10.290908 — biochemistry — Posted on 2020-09-10
2798 Multi-locus genotyping reveals established endemicity of a geographically distinct Plasmodium vivax population in Mauritania, West Africa
Ba, H.; Auburn, S.; Jacob, C. G.; Goncalves, S.; Duffy, C. W.; Stewart, L. B.; Price, R. N.; Deh, Y. B.; Diallo, M. Y.; Tndia, A.; Kwiatkowski, D. P.; Conway, D.
10.1101/2020.09.10.291005 — microbiology — Posted on 2020-09-10
2801 Gene exchange networks define species-like units in marine prokaryotes
Stepanauskas, R.; Brown, J. M.; Mai, U.; Bezuidt, O.; Pachiadaki, M.; Brown, J.; Biller, S.; Berube, P. M.; Record, N. R.; Mirarab, S.
10.1101/2020.09.10.291518 — microbiology — Posted on 2020-09-10
2802 NLRP3 inflammasome inhibition rescues Hutchinson-Gilford Progeria cellular phenotype and extend longevity of an animal model
Alcocer-Gomez, E.; Castejon-Vega, B.; Nunez-Vasco, J.; Lendines-Cordero, D.; Navarro-Pando, J. M.; Cordero, M. D.
10.1101/2020.09.09.288290 — immunology — Posted on 2020-09-10
2807 Automatic Traits Extraction and Fitting for Field High-throughput Phenotyping Systems
Guo, X.; Qiu, Y.; Nettleton, D.; Yeh, C.-T.; Zheng, Z.; Hey, S.; Schnable, P. S.
10.1101/2020.09.09.289769 — plant biology — Posted on 2020-09-10
2808 CECR2 Drives Breast Cancer Metastasis by Suppressing Macrophage Inflammatory Responses
Zhang, M.; Liu, Z.; Aoshima, K.; An, Y.; Aoshima, A.; Chan, L. H.; Lang, S.; Sun, H.; Rutter, S.; Booth, C. J.; Bossuyt, V.; Morrow, J.; Pusztai, L.; Rimm, D.; Yin, M.; Yan, Q.
10.1101/2020.09.10.291799 — cancer biology — Posted on 2020-09-10
2809 Inhibition of USP28 overcomes Cisplatin-Resistance of Squamous Tumors by Suppression of the Fanconi Anemia Pathway.
Prieto-Garcia, C.; Hartmann, O.; Reissland, M.; Fischer, T.; Maier, C. R.; Rosenfeldt, M.; Schuelein-Voelk, C.; Klann, K.; Kalb, R.; Dikic, I.; Muench, C.; Diefenbacher, M. E.
10.1101/2020.09.10.291278 — cancer biology — Posted on 2020-09-10
2810 DETECTION OF INCIPIENT PANCREATIC CANCER WITH NOVEL TUMOR-SPECIFIC ANTIBODIES IN MOUSE MODELS
Oni, T. E.; Bautista, C.; Merrill, J. R.; Goos, J. A. C. M.; Rivera, K. D.; Miyabayashi, K.; Biffi, G.; Garcia, L.; Plenker, D.; Patel, H.; Elyada, E.; Samaritano, M.; Yu, K. H.; Pappin, D. J.; Goggins, M. G.; Hruban, R. H.; Lewis, J. S.; Yeh, J. T.; Tuveson, D. A.
10.1101/2020.09.10.292193 — cancer biology — Posted on 2020-09-10
2812 LIQA: Long-read Isoform Quantification and Analysis
Hu, Y.; Fang, L.; Chen, X.; Zhong, J. F.; Li, M.; Wang, K.
10.1101/2020.09.09.289793 — bioinformatics — Posted on 2020-09-10
2814 In situ photopatterning of cell laden biomaterials for spatially organized 3D cell cultures in a microfluidic chip
Ortiz-Cardenas, J. E.; Zatorski, J. M.; Montalbine, A. N.; Arneja, A.; Luckey, C. J.; Pompano, R. R.
10.1101/2020.09.09.287870 — bioengineering — Posted on 2020-09-10
2815 Glycosyltransferase POMGNT1 deficiency affects N-cadherin-mediated cell-cell adhesion
Noor, S. I.; Hoffmann, M.; Rinis, N.; Bartels, M. F.; Winterhalter, P.; Hoelscher, C.; Henning, R.; Himmelreich, N.; Thiel, C.; Ruppert, T.; Rapp, E.; Strahl, S.
10.1101/2020.09.09.289306 — biochemistry — Posted on 2020-09-10
2816 New insights into homoeologous copy number variations in the hexaploid wheat genome
Juery, C.; Concia, L.; De Oliveira, R.; Papon, N.; Ramirez-Gonzalez, R.; Benhamed, M.; Uauy, C.; Choulet, F.; Paux, E.
10.1101/2020.09.09.289447 — genomics — Posted on 2020-09-10
2819 High-throughput discovery and characterization of human transcriptional effectors
Tycko, J.; DelRosso, N.; Hess, G. T.; Aradhana, ; Banerjee, A.; Mukund, A.; Van, M. V.; Ego, B. K.; Yao, D.; Spees, K.; Suzuki, P.; Marinov, G. K.; Kundaje, A.; Bassik, M. C.; Bintu, L.
10.1101/2020.09.09.288324 — genetics — Posted on 2020-09-10
2821 Pancreatic Beta Cell Autophagy is Impaired in Type 1 Diabetes
Muralidharan, C.; Conteh, A. M.; Marasco, M. R.; Crowder, J. J.; Kuipers, J.; de Boer, P.; Giepmans, B. N. G.; Linnemann, A. K.
10.1101/2020.09.10.291443 — cell biology — Posted on 2020-09-10
2822 A single nuclei transcriptomic analysis of the Atlantic salmon gill through smoltification and seawater transfer
West, A. C.; Mizoro, Y.; Wood, S. H.; Ince, L. M.; Iversen, M.; Jorgensen, E. H.; Nome, T.; Sandve, S. R.; Loudon, A. S. I.; Hazlerigg, D. G.
10.1101/2020.09.03.281337 — molecular biology — Posted on 2020-09-10
2823 Chronic morphine administration differentially modulates viral reservoirs in SIVmac251 infected rhesus macaque model
Acharya, A.; Olwenyi, O. A.; Thurman, M.; Pandey, K.; Morsey, B. M.; Lamberty, B.; Ferguson, N.; Callen, S.; Fang, Q.; Buch, S. J.; Fox, H. S.; Byrareddy, S. N.
10.1101/2020.09.09.290700 — molecular biology — Posted on 2020-09-10
2824 Transcriptomic, protein-DNA interaction, and metabolomic studies of VosA, VelB, and WetA in Aspergillus nidulans asexual spores
Wu, M.-Y.; Mead, M. E.; Lee, M.-K.; Neuhaus, G. F.; Adpressa, D. A.; Martien, J. I.; Son, Y.-E.; Moon, H.; Amador-Noguez, D.; Han, K.-H.; Rokas, A.; Loesgen, S.; Yu, J.-H.; Park, H.-S.
10.1101/2020.09.09.290809 — microbiology — Posted on 2020-09-10
2825 Quantification of discrete gut bacterial strains following fecal transplantation for recurrent Clostridioides difficile infection demonstrates long-term stable engraftment in non-relapsing recipients
Aggarwala, V.; Mogno, I.; Li, Z.; Yang, C.; Britton, G. J.; Chen-Liaw, A.; Mitcham, J.; Bongers, G.; Gevers, D.; Clemente, J. C.; Colombel, J.-F.; Grinspan, A.; Faith, J. J.
10.1101/2020.09.10.292136 — immunology — Posted on 2020-09-10
2827 A P300 brain-computer interface with a reduced visual field
Kirasirova, L.; Bulanov, V.; Ossadtchi, A.; Kolsanov, A.; Pyatin, V.; Lebedev, M.
10.1101/2020.09.07.285379 — neuroscience — Posted on 2020-09-10
2828 Distinct genetic bases for plant root responses to lipo-chitooligosaccharide signal molecules from distinct microbial origins
Bensmihen, S.; Bonhomme, M.; Andre, O.; Amblard, E.; Garcia, M.; Maillet, F.; Puech-Pages, V.; gough, C.; Fort, S.; Cottaz, S.; Becard, G.; Jacquet, C.
10.1101/2020.09.09.285668 — plant biology — Posted on 2020-09-10
2829 Migration through a major Andean ecogeographic disruption as a driver of genotypic and phenotypic diversity in a wild tomato species
Landis, J. B.; Miller, C. M.; Broz, A. K.; Bennett, A. A.; Carrasquilla-Garcia, N.; Cook, D. R.; Last, R. L.; Bedinger, P. A.; Moghe, G. D.
10.1101/2020.09.09.289744 — plant biology — Posted on 2020-09-10
2831 A smartphone app for individual anesthetic calculation decreased anesthesia-related mortality in mice
Jara, C. P.; Carraro, R. S.; Zanesco, A.; Andrade, B.; Moreira, K.; Nogueira, G.; Souza, B.; Prado, T. P.; Povoa, V.; Velloso, L. A.; De Araujo, E. P.
10.1101/2020.09.09.289728 — pharmacology and toxicology — Posted on 2020-09-10
2833 Supraphysiological testosterone induces ferroptosis and activates NF-kappaB mediated immune pathways in prostate cancer through nucleophagy
Mendonca, J.; Kumar, R.; Owoyemi, O.; Boyapati, K.; Thomas, N.; Kanacharoen, S.; Coffey, M.; Topiwala, D.; Gomes, C.; Ozbek, B.; Jones, T.; Rosen, M.; Dong, L.; Wiens, S.; Brennen, W. N.; Isaacs, J.; De Marzo, A. M.; Markowski, M.; Antonarakis, E. S.; Qian, D.; Pienta, K.; Pardoll, D.; Carducci, M.; Denmeade, S.; Kachhap, S.
10.1101/2020.09.10.286252 — cancer biology — Posted on 2020-09-10
2834 Molecular basis for SARS-CoV-2 spike affinity for human ACE2 receptor
Delgado, J. M.; Duro, N.; Rogers, D. M.; Tkatchenko, A.; Pandit, S. A.; Varma, S.
10.1101/2020.09.10.291757 — biophysics — Posted on 2020-09-10
2838 An in vitro human-based fracture gap model - Mimicking the crosstalk between bone and immune cells
Pfeiffenberger, M.; Damerau, A.; Ponomarev, I.; Bucher, C. H.; Chen, Y.; Barnewitz, D.; Thoene-Reineke, C.; Hoff, P.; Buttgereit, F.; Gaber, T.; Lang, A.
10.1101/2020.06.26.165456 — bioengineering — Posted on 2020-09-10
2842 Chromosome-level Genome Assembly of a Regenerable Maize Inbred Line A188
Lin, G.; He, C.; Zheng, J.; Koo, D.-H.; Le, H.; Zheng, H.; Tamang, T. M.; Lin, J.; Liu, Y.; Zhao, M.; Hao, Y.; McFarland, F.; Wang, B.; Qin, Y.; Tang, H.; McCarty, D. R.; Wei, H.; Cho, M.-J.; Park, S.; Kaeppler, H.; Kaeppler, S.; Liu, Y.; Springer, N. M.; Schnable, P. S.; Wang, G.; White, F. F.; Liu, S.
10.1101/2020.09.09.289611 — genomics — Posted on 2020-09-10
2843 IFT-A deficiency in juvenile mice impairs biliary development and exacerbates ADPKD liver disease
Wang, W.; Pottorf, T. S.; Wang, H. H.; Dong, R.; Kavanaugh, M.; Cornelius, J. T.; Apte, U.; Pritchard, M.; Sharma, M.; Tran, P.
10.1101/2020.09.10.289645 — genetics — Posted on 2020-09-10
2846 Foraging strategies under extreme events: Contrasting adaptations by benthic macrofauna to drastic biogeochemical disturbance
Wang, Y. V.; Lebrato, M.; Tseng, L.-C.; Larsen, T.; Smith-Sanchez, N.; Lee, P.-W.; Molinero, J.-C.; Hwang, J.-S.; Chan, T.-Y.; Garbe-Schoenberg, D.
10.1101/2020.09.09.288985 — ecology — Posted on 2020-09-10
2847 Specific breeding system and ploidy interactions increase niche adaptability in potatoes
Fumia, N.; Rubinoff, D.; Zenil-Ferguson, R.; Pironon, S.; Khoury, C.; Gore, M. A.; Kantar, M. B.
10.1101/2020.09.09.290429 — ecology — Posted on 2020-09-10
2851 Epigenetic clock and methylation studies in vervet monkeys
Jasinska, A. J.; Haghani, A.; Zoller, J. A.; Li, C. Z.; Arneson, A.; Ernst, J.; Kavanagh, K.; Jorgensen, M. J.; Mattison, J. A.; Wojta, K.; Choi, O.-W.; DeYoung, J.; Li, X.; Rao, A. W.; Coppola, G.; Freimer, N. B.; Woods, R. P.; Horvath, S.
10.1101/2020.09.09.289801 — developmental biology — Posted on 2020-09-10
2853 Fine-tuning of Epithelial EGFR signals Supports Coordinated Mammary Gland Development
Samocha, A.; Doh, H.; Sitarama, V.; Nguyen, Q.; Gbenedio, O.; Rudolf, J.; Eckalbar, W.; Barczak, A.; Miao, Y.; Garcia, C.; Lawson, D.; Werb, Z.; Kessenbrock, K.; Depeille, P.; Roose, J.
10.1101/2020.09.10.291872 — cell biology — Posted on 2020-09-10
2855 Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons
Squires, K. E.; Gerber, K. J.; Tillman, M. C.; Lustberg, D. J.; Montanez-Miranda, C.; Zhao, M.; Ramineni, S.; Scharer, C. D.; Shu, F.-j.; Schroeder, J. P.; Ortlund, E. A.; Weinshenker, D.; Dudek, S. M.; Hepler, J. R.
10.1101/2020.09.10.289991 — molecular biology — Posted on 2020-09-10
2858 Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition
Greaney, A. J.; Starr, T. N.; Gilchuk, P.; Zost, S. J.; Binshtein, E.; Loes, A. N.; Hilton, S. K.; Huddleston, J.; Eguia, R.; Crawford, K. H.; Dingens, A. S.; Nargi, R. S.; Sutton, R. E.; Suryadevara, N.; Rothlauf, P. W.; Liu, Z.; Whelan, S. P.; Carnahan, R. H.; Crowe, J. E.; Bloom, J. D.
10.1101/2020.09.10.292078 — microbiology — Posted on 2020-09-10
2861 Conserved interactions required for in vitro inhibition of the main protease of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Shitrit, A.; Zaidman, D.; Kalid, O.; Bloch, I.; Doron, D.; Yarnizky, T.; Buch, I.; Segev, I.; Ben-Zeev, E.; Segev, E.; Kobiler, O.
10.1101/2020.09.10.288720 — microbiology — Posted on 2020-09-10
2863 Susceptibility of domestic swine to experimental infection with SARS-CoV-2
Pickering, B.; Smith, G.; Pinette, M.; Embury-Hyatt, C.; Moffat, E.; Marszal, P.; Lewis, C. E.
10.1101/2020.09.10.288548 — microbiology — Posted on 2020-09-10
2864 Human neonatal B cell immunity differs from the adult version by conserved Ig repertoires and rapid, but transient response dynamics
Budeus, B.; Kibler, A.; Brauser, M.; Homp, E.; Bronischewski, K.; Ross, A.; Goergens, A.; Weniger, M. A.; Dunst, J.; Kreslavskiy, T.; Vitoriano, S.; Murke, F.; Oakes, C. C.; Rusch, P.; Andrikos, D.; Kern, P.; Koeniger, A.; Lindemann, M.; Johansson, P.; Hansen, W.; Lundell, A.-C.; Rudin, A.; Duerig, J.; Giebel, B.; Hoffmann, D.; Kueppers, R.; Seifert, M.
10.1101/2020.08.11.245985 — immunology — Posted on 2020-09-10
2865 Systematic comparison of high-throughput single-cell RNA-seq methods for immune cell profiling
Yamawaki, T. M.; Lu, D. R.; Ellwanger, D. C.; Bhatt, D.; Manzanillo, P.; Zhou, H.; Yoon, O. K.; Homann, O.; Wang, S.; Li, C.-M. K.
10.1101/2020.09.04.283499 — immunology — Posted on 2020-09-10
2867 Proliferation of DBLOX Peroxidase-Expressing Oenocytes Maintains Innate Immune Memory in Primed Mosquitoes
Gomes, F. M.; Tyner, M. D. W.; Barletta, A. B. F.; Yenkoidiok-Douti, L.; Canepa, G. E.; Molina-Cruz, A.; Barillas-Mury, C.
10.1101/2020.09.09.290312 — immunology — Posted on 2020-09-10
2868 Bmp8a Is a Novel Player in Regulation of Antiviral Immunity
Zhong, S.; Li, H.; Wang, Y.; Wang, Y.; Ji, G.; Li, H.; Zhang, S.; Liu, Z.
10.1101/2020.08.09.243519 — immunology — Posted on 2020-09-10
2869 Simultaneous aerosol and intra-muscular immunization with influenza vaccine induces powerful protective local T cell and systemic Ab immune responses in pigs
Martini, V.; Paudyal, B.; Chrun, T.; McNee, A.; Edmans, M.; Maze, E.; Clark, B.; Nunez, A.; Dolton, G.; Sewell, A.; Beverley, P.; MacLoughlin, R.; Townsend, A.; Tchilian, E.
10.1101/2020.09.10.291625 — immunology — Posted on 2020-09-10
2871 Dissociation between catecholamines and acetylcholine in the human cerebral cortex
Pfeffer, T.; Ponce-Alvarez, A.; Meindertsma, T.; Gahnstrom, C.; van den Brink, R. L.; Nolte, G.; Tsetsos, K.; Engel, A. K.; Deco, G.; Donner, T. H.
10.1101/2020.06.25.171199 — neuroscience — Posted on 2020-09-10
2872 Paranode stability requires UNC5B expression by oligodendrocytes
de Faria, O.; Nakamura, D. S.; Clemot, S.; Kim, D.; Mocanu, M. V.; Pilgram, R.; Bin, J. M.; Wong, E. W.; Shmuel, A.; Sadikot, A.; Ackerman, S. L.; Kennedy, T. E.
10.1101/2020.08.06.234906 — neuroscience — Posted on 2020-09-10
2873 Serotonergic Effects on Interoception
Livermore, J. J. A.; Holmes, C. L.; Moga, G.; Adamatzky, K.; Critchley, H.; Garfinkel, S.; Campbell-Meiklejohn, D.
10.1101/2020.08.28.262550 — neuroscience — Posted on 2020-09-10
2879 ImmunoCluster: A computational framework for the non-specialist to immune profile cellular heterogeneity using liquid and imaging mass, and flow cytometry datasets
Opzoomer, J. W.; Timms, J. A.; Blighe, K.; Mourikis, T. P.; Chapuis, N.; Bekoe, R.; Kareemaghay, S.; Nocerino, P.; Apollonio, B.; Ramsay, A. G.; Tavassoli, M.; Harrison, C.; Ciccarelli, F.; Parker, P.; Fontenay, M.; Barber, P.; Arnold, J. N.; Kordasti, S.
10.1101/2020.09.09.289033 — systems biology — Posted on 2020-09-10
2881 Machine learning-based investigation of the cancer protein secretory pathway
Saghaleyni, R.; Muhammad, A. S.; Bangalore, P.; Nielsen, J.; Robinson, J. L.
10.1101/2020.09.09.289413 — systems biology — Posted on 2020-09-10
2883 Convergent network effects along the axis of gene expression during prostate cancer progression
Charmpi, K.; Guo, T.; Zhong, Q.; Wagner, U.; Sun, R.; Toussaint, N. C.; Fritz, C.; Yuan, C.; Chen, H.; Rupp, N. J.; Christiansen, A.; Rutishauser, D.; Ruschoff, J. H.; Fankhauser, C.; Saba, K.; Poyet, C.; Hermanns, T.; Oehl, K.; Moore, A. L.; Beisel, C.; Calzone, L.; Martignetti, L.; Zhang, Q.; Zhu, Y. J.; Martinez, M. R.; Manica, M.; Haffner, M. C.; Aebersold, R.; Wild, P. J.; Beyer, A.
10.1101/2020.02.16.950378 — systems biology — Posted on 2020-09-10
2886 Chromatin accessibility landscapes activated by cell surface and intracellular immune receptors
Ding, P.; Sakai, T.; Shrestha, R. K.; Perez, N. M.; Guo, W.; Ngou, B. P. M.; He, S.; Liu, C.; Feng, X.; Zhang, R.; Vandepoele, K.; MacLean, D.; Jones, J. D.
10.1101/2020.06.17.157040 — plant biology — Posted on 2020-09-10
2890 Gene expression has more power for predicting in vitro cancer cell vulnerabilities than genomics
Dempster, J. M.; Krill-Burger, J.; Warren, A.; McFarland, J.; Boehm, J. S.; Vazquez, F.; Hahn, W.; Golub, T.; Tsherniak, A.
10.1101/2020.02.21.959627 — cancer biology — Posted on 2020-09-10
2891 Feasibility of Integrating Canine Olfaction with Chemical and Microbial Profiling of Urine to Detect Lethal Prostate Cancer
Guest, C.; Harris, R.; Sfanos, K. S.; Shrestha, E.; Partin, A. W.; Trock, B.; Mangold, L.; Bader, R.; Kozak, A.; Mclean, S.; Simons, J.; Soule, H.; Johnson, T.; Lee, W.-Y.; Gao, Q.; Aziz, S.; Stathatou, P.; Thaler, S.; Foster, S.; Mershin, A.
10.1101/2020.09.09.288258 — cancer biology — Posted on 2020-09-10
2892 PAX8 orchestrates an angiogenic program through interaction with SOX17
Chaves-Moreira, D.; Mitchell, M. A.; Arruza, C.; Rawat, P.; Sidoli, S.; Nameki, R.; Reddy, J.; Corona, R. I.; Ma, S.; Winterhoff, B.; Konecny, G. E.; Garcia, B. A.; Brady, D. C.; Lawrenson, K.; Morin, P. J.; Drapkin, R.
10.1101/2020.09.09.290387 — cancer biology — Posted on 2020-09-10
2897 Inhibitor binding influences the protonation states of histidines in SARS-CoV-2 main protease
Pavlova, A.; Lynch, D. L.; Daidone, I.; Zanetti-Polzi, L.; Smith, M. D.; Chipot, C.; Kneller, D. W.; Kovalevsky, A.; Coates, L.; Golosov, A. A.; Dickson, C. J.; Velez-Vega, C.; Duca, J. S.; Vermaas, J. V.; Pang, Y. T.; Acharya, A.; Parks, J. M.; Smith, J. C.; Gumbart, J. C.
10.1101/2020.09.07.286344 — biophysics — Posted on 2020-09-10
2901 Epitope - based peptide vaccine against glycoprotein GPC precursor of Lujo virus using immunoinformatics approaches
Mohammed, A. A.; Elkhalifa, M. E.; Elamin, K. E.; Mohammed, R. A.; Ibrahim, M. E.; Dirar, A. I.; Migdar, S. H.; Hamid, M. A.; Elawad, E. H.; Abdelsalam, S. O.; Hassan, M. A.
10.1101/2020.09.09.287771 — bioinformatics — Posted on 2020-09-10
2904 Nanoparticle-mediated microRNA-145 Delivery for Vascular Smooth Muscle Cell Phenotype Modulation and Atherosclerosis Treatment
Chin, D.; Poon, C.; Wang, J.; Joo, J.; Ong, V.; Jiang, Z.; Cheng, K.; Plotkin, A.; Magee, G. A.; Chung, E. J.
10.1101/2020.09.09.290361 — bioengineering — Posted on 2020-09-10
2905 ARL15 modulates magnesium homeostasis through N-glycosylation of CNNMs
Zolotarov, Y.; Ma, C.; Gonzalez-Recio, I.; Hardy, S.; Franken, G.; Uetani, N.; Latta, F.; Kostantin, E.; Boulais, J.; Thibault, M.-P.; Cote, J.-F.; Diaz Moreno, I.; Diaz Quintana, A.; Hoenderop, J. G. J.; Martinez-Cruz, L. A.; Tremblay, M. L.; de Baaij, J. H. F.
10.1101/2020.09.09.289835 — biochemistry — Posted on 2020-09-10
2909 Association of gut microbiota with metabolism in juvenile Atlantic Salmon
Dvergedal, H.; Sandve, S. R.; Klemetsdal, G.; Angell, I. L.; Rudi, K.
10.1101/2020.02.10.941245 — genetics — Posted on 2020-09-10
2910 Genome-wide association and prediction studies using a grapevine diversity panel give insights into the genetic architecture of several traits of interest
Flutre, T.; Le Cunff, L.; Fodor, A.; Launay, A.; Romieu, C.; Berger, G.; Bertrand, Y.; Beccavin, I.; Bouckenooghe, V.; Roques, M.; Pinasseau, L.; Verbaere, A.; Sommerer, N.; Cheynier, V.; Bacilieri, R.; Boursiquot, J.-M.; Lacombe, T.; Laucou, V.; This, P.; Peros, J.-P.; Doligez, A.
10.1101/2020.09.10.290890 — genetics — Posted on 2020-09-10
2914 Adaptability and evolution of the cell polarization machinery in budding yeast
Brauns, F.; Inigo de la Cruz, L. M.; Daalman, W. K.-G.; de Bruin, I.; Halatek, J.; Laan, L.; Frey, E.
10.1101/2020.09.09.290510 — evolutionary biology — Posted on 2020-09-10
2918 The role of prolines and glycine in transmembrane domain of LAT
Glatzova, D.; Mavila, H.; Saija, M. C.; Chum, T.; Cwiklik, L.; Brdicka, T.; Cebecauer, M.
10.1101/2020.08.10.244251 — cell biology — Posted on 2020-09-10
2921 Targeting of Mammalian Glycans Enhances Phage Predation in the Gastrointestinal Tract
Green, S. I.; Gu Liu, C.; Yu, M.; Gibson, S.; Salmen, W.; Rajan, A.; Carter, H. E.; Clark, J. R.; Song, X.; Ramig, R. F.; Trautner, B. W.; Kaplan, H. B.; Maresso, A. W.
10.1101/2020.07.20.212829 — microbiology — Posted on 2020-09-10
2922 Visualizing and isolating iron-reducing microorganisms at single cell level
Gan, C.; Wu, R.; Luo, Y.; Song, J.; Luo, D.; Li, B.; Yang, Y.; Xu, M.
10.1101/2020.09.09.290734 — microbiology — Posted on 2020-09-10
2926 Transient cell-in-cell formation underlies tumor resistance to immunotherapy
Gutwillig, A.; Santana-Magal, N.; Farhat-Younis, L.; Rasoulouniriana, D.; Madi, A.; Luxenburg, C.; Cohen, J.; Padmanabhan, K.; Shomron, N.; Shapira, G.; Feinmesser, M.; Zlotnik, O.; Debets, R.; Reticker-Flynn, N. E.; Rider, P.; Carmi, Y.
10.1101/2020.09.10.287441 — immunology — Posted on 2020-09-10
2930 Suppression without inhibition: A novel mechanism in the retina accounts for saccadic suppression
Idrees, S.; Baumann, M. P.; Korympidou, M. M.; Schubert, T.; Kling, A.; Franke, K.; Hafed, Z. M.; Franke, F.; Münch, T. A.
10.1101/2020.08.21.261198 — neuroscience — Posted on 2020-09-10
2932 Neural vulnerability and hurricane-related media predict posttraumatic stress in youth
Dick, A. S.; Silva, K.; Gonzalez, R.; Sutherland, M. T.; Laird, A. R.; Thompson, W. K.; Tapert, S. F.; Squeglia, L. M.; Gray, K. M.; Nixon, S. J.; Cottler, L. B.; La Greca, A. M.; Gurwitch, R. H.; Comer, J. S.
10.1101/2020.08.27.271056 — neuroscience — Posted on 2020-09-10
2935 The rice plastidial phosphorylase participates directly in both sink and source processes
Koper, K.; Hwang, S.-K.; Wood, M.; Singh, S.; Cousins, A.; Kirchhoff, H.; Okita, T. W.
10.1101/2020.07.09.191585 — plant biology — Posted on 2020-09-10
2936 Evolution of kinase polypharmacology across HSP90 drug discovery
Antolin, A. A.; Clarke, P. A.; Collins, I.; Workman, P.; Al-Lazikani, B.
10.1101/2020.09.09.288936 — pharmacology and toxicology — Posted on 2020-09-10
2939 Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs
Kim, J. H.; Megquier, K. J.; Thomas, R.; Sarver, A. L.; Song, J. M.; Kim, Y. T.; Schulte, A. J.; Cheng, N.; Linden, M. A.; Murugan, P.; Oseth, L.; Foster, C. L.; Elvers, I.; Swofford, R.; Turner-Maier, J.; Karlsson, E. K.; Breen, M.; Lindblad-Toh, K.; Modiano, J. F.
10.1101/2020.08.11.246777 — cancer biology — Posted on 2020-09-10
2940 Determination of the molecular reach of the protein tyrosine phosphatase SHP-1
Clemens, L.; Kutuzov, M.; Bayer, K. V.; Goyette, J.; Allard, J.; Dushek, O.
10.1101/2020.09.04.283341 — biophysics — Posted on 2020-09-10
2943 Long-read genome sequencing for the diagnosis of neurodevelopmental disorders
Hiatt, S. M.; Lawlor, J. M.; Handley, L. H.; Ramaker, R. C.; Rogers, B. B.; Partridge, E. C.; Boston, L. B.; Williams, M.; Jenkins, J.; Gray, D. E.; Holt, J. M.; Bowling, K. M.; Bebin, E. M.; Grimwood, J.; Schmutz, J.; Cooper, G. M.
10.1101/2020.07.02.185447 — genomics — Posted on 2020-09-10
2945 Indirect versus Direct Effects of Freshwater Browning on Larval Fish Foraging
Leech, D.; Clift, T. L.; Littlefield, J. L.; Ravagli, N. R.; Spain, J. E.
10.1101/804070 — ecology — Posted on 2020-09-10
2946 Translocation of an arctic seashore plant reveals signs of maladaptation to altered climatic conditions
Hallfors, M. H.; Lehvavirta, S.; Aandahl, T. R.; Lehtimaki, I.; Nilsson, L.-O.; Ruotsalainen, A.-L.; Schulman, L. E.; Hyvarinen, M. T.
10.1101/2020.05.22.109868 — ecology — Posted on 2020-09-10
2947 Early loss of Scribble affects cortical development and interhemispheric connectivity resulting in psychomotor dysregulation.
Ezan, J.; Moreau, M. M.; Mamo, T. M.; Shimbo, M.; Decroo, M.; Richter, M.; Peyroutou, R.; Rachel, R.; Tissir, F.; Calderon de Anda, F.; Sans, N.; Montcouquiol, M.
10.1101/780130 — neuroscience — Posted on 2020-09-10
2950 Statistical analysis and optimality of neural systems
Mlynarski, W.; Hledik, M.; Sokolowski, T. R.; Tkacik, G.
10.1101/848374 — neuroscience — Posted on 2020-09-10
2952 Temperatures that sterilise males better predict global distributions of species than lethal temperatures
Parratt, S. R.; Walsh, B.; Metelmann, S.; White, N.; Manser, A.; Bretman, A.; Hoffmann, A. A.; Snook, R.; Price, T.
10.1101/2020.04.16.043265 — ecology — Posted on 2020-09-10
2957 Accurate transcription start sites enable mining for the cis-regulatory determinants of tissue specific gene expression
Ansariola, M.; Fraser, V. N.; Filichkin, S. A.; Ivanchenko, M. G.; Bright, Z. A.; Gould, R. A.; Ozguc, O. R.; O'Neil, S. T.; Megraw, M.
10.1101/2020.09.01.278424 — genomics — Posted on 2020-09-10
2958 REPRESSION BY HDAC3 AND DAX1 MEDIATES LINEAGE RESTRICTION OF EMBRYONIC STEM CELLS
Olivieri, D.; Papasaikas, P.; Lukonin, I.; Rittirsch, M.; Hess, D.; Smallwood, S.; Stadler, M. B.; Betschinger, J.
10.1101/2020.09.10.291013 — developmental biology — Posted on 2020-09-10
2960 Ligand-independent role of ErbB3 in endocytotic recycling
Saez-Ibanez, A. R.; Scheffler, J. M.; Terabayashi, T.; Daubel, N.; Makinen, T.; Idevall-Hagren, O.; Ferby, I.
10.1101/575449 — cell biology — Posted on 2020-09-10
2961 Allele-specific gene regulation by KDM6A
Ma, W.; Fang, H.; Pease, N.; Filippova, G.; Disteche, C.; Berletch, J.
10.1101/2020.09.09.289926 — molecular biology — Posted on 2020-09-10
2962 Identifying and validating the presence of Guanine-Quadruplexes (G4) within the blood fluke parasite Schistosoma mansoni.
Craven, H.; Bonsignore, R.; Lenis, V.; Santi, N.; Berrar, D.; Swain, M.; Whiteland, H.; Casini, A.; Hoffmann, K.
10.1101/2020.09.09.289975 — microbiology — Posted on 2020-09-10
2963 The atypical Rho GTPase Rnd2 is critical for dentate granule neuron development and anxiety-like behavior during adult but not neonatal neurogenesis
Kerloch, T.; Farrugia, F.; Maitre, M.; Terral, G.; Koehl, M.; Heng, J. I.-T.; Blanchard, M.; Doat, H.; Leste-Lasserre, T.; Goron, A.; Gonzales, D.; Guillemot, F.; Abrous, N.; Pacary, E.
10.1101/2020.09.10.290866 — neuroscience — Posted on 2020-09-10
2964 Perceptual phenotypes: Perceptual gains and losses in synesthesia and schizophrenia
van Leeuwen, T. M.; Sauer, A.; Jurjut, A.-M.; Wibral, M.; Uhlhaas, P.; Singer, W.; Melloni, L.
10.1101/443846 — neuroscience — Posted on 2020-09-10
2965 Classification and Specific Primer Design for Accurate Detection of SARS-CoV-2 Using Deep Learning
Lopez-Rincon, A.; Tonda, A.; Mendoza-Maldonado, L.; Mulders, D.; Molenkamp, R.; Perez-Romero, C. A.; Claassen, E.; Garssen, J.; Kraneveld, A. D.
10.1101/2020.03.13.990242 — bioinformatics — Posted on 2020-09-10
2970 Psilocybin rescues sociability deficits in an animal model of autism
Mollinedo-Gajate, I.; Song, C.; Sintes-Rodriguez, M.; Whelan, T.; Soula, A.; Selimbeyoglu, A.; Hurley, S.; Knöpfel, T.
10.1101/2020.09.09.289348 — neuroscience — Posted on 2020-09-10
2972 Natural sensory context drives diverse brain-wide activity during C. elegans mating
Susoy, V.; Hung, W.; Witvliet, D.; Whitener, J. E.; Wu, M.; Graham, B. J.; Zhen, M.; Venkatachalam, V.; Samuel, A. D. T.
10.1101/2020.09.09.289454 — neuroscience — Posted on 2020-09-10
2973 Ophthalmic Changes in a Spaceflight Analog Are Associated with Brain Functional Reorganization
McGregor, H. R.; Lee, J. K.; Mulder, E.; De Dios, Y.; Beltran, N. E.; Kofman, I. S.; Bloomberg, J. J.; Mulavara, A. P.; Seidler, R. D.
10.1101/2020.09.09.289827 — neuroscience — Posted on 2020-09-10
2974 rSWeeP: A R/Bioconductor package deal with SWeeP sequences representation
Fernandes, D. R.; Kulik, M. G.; Machado, D. J. S.; Marchaukoski, J. N.; Pedrosa, F. O.; De Pierri, C. R.; Raittz, R. T.
10.1101/2020.09.09.290247 — bioinformatics — Posted on 2020-09-10
2976 New mechanism of fibronectin fibril assembly revealed by live imaging and super-resolution microscopy.
Tomer, D.; Munshi, S.; Alexander, B.; French, B.; Vedula, P.; House, A.; Guvendiren, M.; Kashina, A.; Schwarzbauer, J.; Astrof, S.
10.1101/2020.09.09.290130 — cell biology — Posted on 2020-09-10
2977 Phase separation of tunable biomolecular condensates predicted by an interacting particle model
Munoz-Gil, G.; Romero, C.; Mateos, N.; de Llobet Cucalon, L. I.; Beato, M.; Lewenstein, M.; Garcia-Parajo, M. F.; Torreno-Pina, J. A.
10.1101/2020.09.09.289876 — biophysics — Posted on 2020-09-10
2982 PKA-mediated phosphorylation of SPG11/spatacsin regulates binding with a subset of 14-3-3 proteins
Cogo, S.; Tomkins, J. E.; Vavouraki, N.; Forcellato, F.; Franchin, C.; Tessari, I.; Arrigoni, G.; Cendron, L.; Manzoni, C.; Civiero, L.; Lewis, P. A.; Greggio, E.
10.1101/2020.09.09.289009 — cell biology — Posted on 2020-09-10
2983 Metazoan-like kinetochore arrangement masked by the interphase RabI configuration
Jimenez-Martin, A.; Pineda-Santaella, A.; Leon-Perinan, D.; Delgado-Gestoso, D.; Marin-Toral, L.; Fernandez-Alvarez, A.
10.1101/2020.09.09.289066 — cell biology — Posted on 2020-09-10
2984 Selective silencing rather than targeted activation of gene expression underlies fate choice in human hematopoietic stem cells.
Parmentier, R.; Moussy, A.; Chantalat, S.; Racine, L.; Ravi, S.; Gao, N. P.; Stockholm, D.; Corre, G.; Deleuze, J.-F.; Gunawan, R.; Paldi, A.
10.1101/2020.09.09.289751 — cell biology — Posted on 2020-09-10
2988 Characterization of SOX2, OCT4 and NANOG in ovarian cancer tumor-initiating cells
Robinson, M.; Gilbert, S. F.; Waters, J. A.; Lujano-Olazaba, O.; Lara, J.; Holmberg, R.; Alexander, L. J.; Green, S. E.; Burkeen, G.; Patrus, O.; Wang, C.; House, C. D.
10.1101/2020.09.08.288381 — cancer biology — Posted on 2020-09-10
2993 A multi-sensor system provides spatiotemporal oxygen regulation of gene expression in a Rhizobium-legume symbiosis
Poole, P. S.; Rutten, P. J.; Steel, H.; Hood, G. A.; McMurtry, L.; Geddes, B.; Papachristodoulou, A.
10.1101/2020.09.09.289140 — microbiology — Posted on 2020-09-09
2994 The FlhA linker mediates flagellar protein export switching during flagellar assembly
Inoue, Y.; Kida, M.; Kinoshita, M.; Takekawa, N.; Namba, K.; Imada, K.; Minamino, T.
10.1101/2020.09.09.290478 — microbiology — Posted on 2020-09-09
2997 Dissecting the heterogeneous subcortical brain volume of Autism spectrum disorder (ASD) using community detection
Li, T.; Hoogman, M.; Mota, N. R.; Buitelaar, J.; the ENIGMA-ASD Working Group, ; Vasquez, A. A.; Franke, B.; Rooij, D. v.
10.1101/2020.09.09.288993 — neuroscience — Posted on 2020-09-09
2998 Genotypic differences in wheat yield determinants within a NAM population based on elite parents
Basavaraddi, P.; Savin, R.; Sukumaran, S.; Reynolds, M.; Griffiths, S.; Slafer, G.
10.1101/2020.09.08.287763 — physiology — Posted on 2020-09-09
2999 Therapeutic assessment of targeting ASNS combined with L-Asparaginase treatment in solid tumors and investigation of resistance mechanisms
Apfel, V.; Begue, D.; Cordo, V.; Holzer, L.; Martinuzzi, L.; Buhles, A.; Kerr, G.; Barbosa, I.; Naumann, U.; Piquet, M.; Ruddy, D.; Weiss, A.; Ferretti, S.; Almeida, R.; Bonenfant, D.; Tordella, L.; Galli, G. G.
10.1101/2020.09.08.287565 — cancer biology — Posted on 2020-09-09
3001 Diversity and Function of the Eastern Oyster (Crassostrea virginica) Microbiome
Pimentel, Z. T.; Dufault-Thompson, K.; Russo, K. T.; Scro, A. K.; Smolowitz, R.; Gomez-Chiarri, M.; Zhang, Y.
10.1101/2020.09.08.288811 — bioinformatics — Posted on 2020-09-09
3005 CLPX regulates erythroid heme synthesis by control of mitochondrial heme synthesis enzymes and iron utilization
Rondelli, C. M.; Perfetto, M.; Danoff, A.; Bergonia, H.; Gillis, S.; Nicolas, G.; Puy, H.; West, R.; Phillips, J. D.; Yien, Y. Y.
10.1101/2020.09.09.289660 — biochemistry — Posted on 2020-09-09
3006 Chromosome-level genome assembly of a benthic associated Syngnathiformes species: the common dragonet, Callionymus lyra
Winter, S.; Prost, S.; De Raad, J.; Coimbra, R.; Wolf, M.; Nebenfuehr, M.; Held, A.; Kurzawe, M.; Papapostolou, R.; Tessien, J.; Bludau, J.; Kelch, A.; Gronefeld, S.; Schoeneberg, Y.; Zeitz, C.; Zapf, K.; Prochotta, D.; Murphy, M.; Sheffer, M. M.; Sonnewald, M.; Nilsson Janke, M. A.; Janke, A.
10.1101/2020.09.08.287078 — genomics — Posted on 2020-09-09
3007 Heteroscedastic regression modeling elucidates gene-by-environment interaction
Domingue, B. W.; Kanopka, K.; Mallard, T. T.; Trejo, S.; Tucker-Drob, E. M.
10.1101/2020.09.08.287888 — genetics — Posted on 2020-09-09
3008 Heritable variation in resistance to the endonuclear parasite Holospora undulata across clades of Paramecium caudatum
Weiler, J.; Zilio, G.; Zeballos, N.; Norgaard, L.; Conce Alberto, W.; Krenek, S.; Kaltz, O.; Bright, L.
10.1101/2020.09.08.288118 — genetics — Posted on 2020-09-09
3009 Transcriptome Alterations in Myotonic Dystrophy Frontal Cortex
Otero, B. A.; Poukalov, K.; Hildebrandt, R. P.; Thornton, C. A.; Jinnai, K.; Fujimura, H.; Kimura, T. T.; Hagerman, K. A.; Sampson, J. B.; Day, J. W.; Wang, E. T.
10.1101/2020.09.09.284505 — genetics — Posted on 2020-09-09
3011 Barriers to gene flow play an important role in miantaining reproductive isolation between two closely related Populus (Salicaceae) species
Yang, T.; Shuyu, L.; Ingvarsson, P. K.; Dandan, Z.; Li, W.; `Abuduhamiti, B.; Zhiqiang, W.; Jianguo, Z.; Zhaoshan, W.
10.1101/2020.09.08.287292 — evolutionary biology — Posted on 2020-09-09
3012 Pervasive selection pressure in wild and domestic pigs
Leno-Colorado, J.; Guirao-Rico, S.; Perez-Enciso, M.; Ramos-Onsins, S. E.
10.1101/2020.09.09.289439 — evolutionary biology — Posted on 2020-09-09
3013 The erosion of biodiversity and biomass in the Atlantic Forest biodiversity hotspot
Lima, R. A. F.; de Oliveira, A. A.; Pitta, G. R.; de Gasper, A. L.; Vibrans, A. C.; Chave, J.; ter Steege, H.; Prado, P. I.
10.1101/2020.09.08.287938 — ecology — Posted on 2020-09-09
3015 THE BENEFITS OF MYCORRHIZAE ARE FREQUENCY-DEPENDENT: A CASE STUDY WITH A NON-MYCORRHIZAL MUTANT OF PISUM SATIVUM
McNickle, G. G.; Guinel, F. C.; Sniderhan, A. E.; Wallace, C. A.; Fafard, M. M.; Baltzer, J. L.
10.1101/2020.09.08.288084 — ecology — Posted on 2020-09-09
3017 Host adaptation in gut Firmicutes is associated with sporulation loss and altered colonisation patterns
Browne, H. P.; Almeida, A.; Kumar, N.; Vervier, K.; Adoum, A. T.; Viciani, E.; Dawson, N. J.; Forster, S. C.; Cormie, C.; Goulding, D.; Lawley, T. D.
10.1101/2020.09.09.289504 — microbiology — Posted on 2020-09-09
3019 Evaluation of Safety and Immunogenicity of an Adjuvanted, TH-1 Skewed, Whole Virion Inactivated SARS-CoV-2 Vaccine - BBV152
Ganneru, B.; Jogdand, H.; Dharam, V. K.; Reddy, N.; Prasad, S. D.; Vellimudu, S.; Ella, K. M.; Ravikrishnan, R.; Awasthi, A.; Jose, J.; Rao, P.; Kumar, D.; Ella, R.; Abraham, P.; Yadav, P.; Sapkal, G. N.; Shete, A.; Desphande, G. R.; Mohandas, S.; Basu, A.; Gupta, N.; Bhargava, B.; Mohan, K. V.
10.1101/2020.09.09.285445 — immunology — Posted on 2020-09-09
3022 Stream-Specific Feedback Inputs to the Primate Primary Visual Cortex
Federer, F.; Ta'afua, S.; Merlin, S.; Hassanpour, M. S.; Angelucci, A.
10.1101/2020.03.04.977264 — neuroscience — Posted on 2020-09-09
3028 Single-Cell Resolution of Lineage Trajectories in the Arabidopsis Stomatal Lineage and Developing Leaf
Lopez-Anido, C. B.; Vaten, A.; Smoot, N. K.; Sharma, N.; Guo, V.; Gong, Y.; Anleu-Gil, M. X.; Weimer, A. K.; Bergmann, D. C.
10.1101/2020.09.08.288498 — plant biology — Posted on 2020-09-09
3030 Direct contribution of skeletal muscle mesenchymal progenitors to bone repair
Julien, A.; Kanagalingam, A.; Megret, J.; Luka, M.; Menager, M.; Relaix, F.; COLNOT, C.
10.1101/2020.09.08.287367 — physiology — Posted on 2020-09-09
3031 The pleiotropic effects of the MNK1/2-eIF4E axis support immune suppression and metastasis in a model of postpartum breast cancer.
Guo, Q.; Bartish, M.; Goncalves, C.; Huang, F.; Krisna, S. S.; Preston, S.; Emond, A.; Li, V. Z.; Duerr, C.; Gui, Y.; Cleret-Buhot, A.; Thebault, P.; Lefrere, H.; Lenaerts, L.; Plourde, D.; Su, J.; Mindt, B. C.; Hewgill, S.; Cotechini, T.; Hindmarch, C.; Yang, W.; Khoury, E.; Zhan, Y.; Narykina, V.; Wei, Y.; Floris, G.; Basik, M.; Amant, F.; Quail, D.; Lapointe, R.; Fritz, J.; del Rincon, S. V.; Miller, W. H.
10.1101/2020.09.07.286815 — cancer biology — Posted on 2020-09-09
3033 Chromatin accessibility analysis uncovers regulatory element landscape in prostate cancer progression
Uusi-Mäkelä, J.; Afyounian, E.; Tabaro, F.; Häkkinen, T.; Lussana, A.; Shcherban, A.; Annala, M.; Nurminen, R.; Kivinummi, K.; Tammela, T. L. J.; Urbanucci, A.; Latonen, L.; Kesseli, J.; Granberg, K. J.; Visakorpi, T.; Nykter, M.
10.1101/2020.09.08.287268 — cancer biology — Posted on 2020-09-09
3037 Universal Spectrum Explorer: A standalone (web-)application for cross-resource spectrum comparison
Schmidt, T.; Samaras, P.; Dorfer, V.; Panse, C.; Kockmann, T.; Bichmann, L.; van Puyvelde, B.; Perez-Riverol, Y.; Deutsch, E. W.; Kuster, B.; Wilhelm, M.
10.1101/2020.09.08.287557 — bioinformatics — Posted on 2020-09-09
3038 Effects of Healthy Aging on Right Ventricular Structure and Biomechanical Properties
Sharifi Kia, D.; Shen, Y.; Bachman, T. N.; Goncharova, E. A.; Kim, K.; Simon, M. A.
10.1101/2020.09.08.288332 — bioengineering — Posted on 2020-09-09
3040 Predominant activation of 11-oxygenated androgens by peripheral blood mononuclear cells
Schiffer, L.; Bossey, A.; Taylor, A. E.; Akerman, I.; Scheel-Toellner, D.; Storbeck, K.-H.; Arlt, W.
10.1101/2020.09.08.288316 — biochemistry — Posted on 2020-09-09
3042 Unraveling molecular mechanisms of immunity and cancer-resistance using the genomes of the Neotropical bats Artibeus jamaicensis and Pteronotus mesoamericanus
Scheben, A.; Mendivil Ramos, O.; Kramer, M.; Goodwin, S.; Oppenheim, S. J.; Becker, D. J.; Schatz, M. C.; Simmons, N. B.; Siepel, A.; McCombie, W. R.
10.1101/2020.09.09.290502 — genomics — Posted on 2020-09-09
3043 Cell culture-based shark karyotyping as a resource for chromosome-scale genome analysis
Uno, Y.; Nozu, R.; Kiyatake, I.; Higashiguchi, N.; Sodeyama, S.; Murakumo, K.; Sato, K.; Kuraku, S.
10.1101/2020.09.08.286724 — genomics — Posted on 2020-09-09
3045 Regarding the F-word: the effects of data Filtering on inferred genotype-environment associations
Ahrens, C. W.; Jordan, R.; Bragg, J.; Harrison, P. A.; Hopley, T.; Bothwell, H.; Murray, K.; Steane, D.; Whale, J.; Byrne, M.; Andrew, R.; Rymer, P.
10.1101/2020.09.08.288308 — genomics — Posted on 2020-09-09
3046 Exploring genetic resistance to Infectious Salmon Anaemia Virus in Atlantic salmon by genome-wide association and RNA sequencing
Gervais, O.; Barria, A.; Papadopoulou, A.; Gratacap, R.; Hillestad, B.; Tinch, A. E.; Martin, S. A. M.; Robledo, D.; Houston, R. D.
10.1101/2020.09.08.287052 — genetics — Posted on 2020-09-09
3051 NEON Crowns: a remote sensing derived dataset of 100 million individual tree crowns
Weinstein, B.; Marconi, S.; Bohlman, S.; Zare, A.; Singh, A.; Graves, S.; White, E.
10.1101/2020.09.08.287839 — ecology — Posted on 2020-09-09
3052 Global drivers of eukaryotic plankton biogeography in the sunlit ocean
SOMMERIA-KLEIN, G.; Watteaux, R.; Iudicone, D.; Bowler, C.; Morlon, H.
10.1101/2020.09.08.287524 — ecology — Posted on 2020-09-09
3053 Glypican4 mediates Wnt transport between germ layers via signaling filopodia
Hu, B.; Kakkerla Balaraju, A.; Rodriguez, J. J.; Gao, Y.; Nguyen, N. T.; Steen, H.; Suhaib, S.; Chen, S.; Lin, F.
10.1101/2020.09.08.288613 — developmental biology — Posted on 2020-09-09
3054 Molecular-scale visualization of sarcomere contraction within native cardiomyocytes
Burbaum, L.; Schneider, J.; Scholze, S.; Boettcher, R. B.; Baumeister, W.; Schwille, P.; Plitzko, J. M.; Jasnin, M.
10.1101/2020.09.09.288977 — cell biology — Posted on 2020-09-09
3055 Unprotected Peptide Macrocyclization and Stapling via A Fluorine-Thiol Displacement Reaction
Islam, M. S.; Junod, S. L.; Zhang, S.; Buuh, Z. Y.; Guan, Y.; Kaneria, K. H.; Lyu, Z.; Voelz, V.; Yang, W.; Wang, R. E.
10.1101/2020.09.09.290379 — cell biology — Posted on 2020-09-09
3058 Interaction network of SARS-CoV-2 with host receptome through spike protein
Gu, Y.; Cao, J.; Zhang, X.; Gao, H.; Wang, Y.; Wang, J.; Zhang, J.; Shen, G.; Jiang, X.; Yang, J.; Zheng, X.; Xu, J.; Zhang, C. C.; Lan, F.; Qu, D.; Zhao, Y.; Xu, G.; Xie, Y.; Luo, M.; Lu, Z.
10.1101/2020.09.09.287508 — microbiology — Posted on 2020-09-09
3059 Influenza A virus-induced thymus atrophy differentially affects dynamics of conventional and regulatory T cell development
Elfaki, Y.; Robert, P. A.; Binz, C.; Falk, C. S.; Bruder, D.; Prinz, I.; Flöss, S.; Meyer-Hermann, M.; Hühn, J.
10.1101/2020.09.09.274795 — immunology — Posted on 2020-09-09
3060 Prevention of EAE by PEGylated Antigenic Peptide
Pfeil, J.; Simonetti, M.; Lauer, U.; von Thulen, B.; Durek, P.; Poulsen, C.; Pawlowska, J.; Kroger, M.; Krahmer, R.; Leenders, F.; Hoffmann, U.; Hamann, A.
10.1101/2020.09.08.280875 — immunology — Posted on 2020-09-09
3063 Where and how does d-amphetamine act to reveal antipsychotic-induced dopamine supersensitivity in rats?
Servonnet, A.; Allain, F.; Gravel-Chouinard, A.; Hernandez, G.; Bourdeau Caporuscio, C.; Legrix, M.; Levesque, D.; Rompre, P.-P.; Samaha, A.-N.
10.1101/2020.09.08.287664 — pharmacology and toxicology — Posted on 2020-09-09
3064 Inhibition of guanosine monophosphate synthetase (GMPS) blocks glutamine metabolism and prostate cancer growth in vitro and in vivo
Wang, Q.; Guan, Y. F.; Hancock, S. E.; Wahi, K.; van Geldermalsen, M.; Zhang, B. K.; Pang, A.; Nagarajah, R.; Mak, B.; Horvath, L. G.; Turner, N.; Holst, J.
10.1101/2020.09.07.286997 — cancer biology — Posted on 2020-09-09
3065 Tumors widely express hundreds of embryonic germline genes
Bruggeman, J. W.; Irie, N.; Lodder, P.; van Pelt, A. M. M.; Koster, J.; Hamer, G.
10.1101/2020.09.08.287284 — cancer biology — Posted on 2020-09-09
3069 KuLGaP: A Selective Measure for Assessing Therapy Response in Patient-Derived Xenografts
Ortmann, J.; Rampasek, L.; Tai, E.; Mer, A. S.; Shi, R.; Mascaux, C.; Fares, A.; Pham, N.-A.; Beri, G.; Eeles, C.; Tkachuk, D.; Ho, C.; Sakashita, S.; Weiss, J.; Jiang, X.; Liu, G.; Cescon, D. W.; O'Brien, C.; Guo, S.; Tsao, M.-S.; Haibe-Kains, B.; Goldenberg, A.
10.1101/2020.09.08.287573 — bioinformatics — Posted on 2020-09-09
3070 Rapid, high-yield production of full-length SARS-CoV-2 spike ectodomain by transient gene expression in CHO cells
Stuible, M.; Gervais, C.; Lord-Dufour, S.; Perret, S.; L'Abbe, D.; Schrag, J.; St-Laurent, G.; Durocher, Y.
10.1101/2020.09.08.286732 — bioengineering — Posted on 2020-09-09
3074 Genomic selection to optimize doubled haploid-based hybrid breeding in maize
Li, J.; Cheng, D.; Guo, S.; Yang, Z.; Chen, M.; Chen, C.; Jiao, Y.; Li, W.; Liu, C.; Zhong, Y.; Qi, X.; Yang, J.; Chen, S.
10.1101/2020.09.08.287672 — genetics — Posted on 2020-09-09
3077 Steric-Free Bioorthogonal Labeling of Acetylation Substrates Based on a Fluorine-Thiol Displacement Reaction (FTDR)
Lyu, Z.; Zhao, Y.; Buuh, Z. Y.; Gorman, N.; Goldman, A. R.; Islam, M. S.; Tang, H.-Y.; Wang, R. E.
10.1101/2020.09.09.290221 — cell biology — Posted on 2020-09-09
3080 Neonatal enteropathogenic Escherichia coli infection disrupts microbiota-gut-brain axis signaling
Hennessey, C.; Barboza, M.; Brust-Mascher, I.; Knotts, T.; Sladek, J.; Pusceddu, M.; Stokes, P.; Rabasa, G.; Honeycutt, M.; Walsh, O.; Reardon, C.; Gareau, M.
10.1101/2020.09.08.288803 — microbiology — Posted on 2020-09-09
3081 Ecological niche adaptation of a bacterial pathogen associated with reduced zoonotic potential
Kirkwood, M.; Vohra, P.; Bawn, M.; Thilliez, G.; Pye, H.; Tanner, J.; Chintoan-Uta, C.; Branchu, P.; Petrovska, L.; Dallman, T. J.; Hall, N.; Stevens, M.; Kingsley, R. A.
10.1101/2020.09.09.288845 — microbiology — Posted on 2020-09-09
3082 Interaction network of SARS-CoV-2 with host receptome through spike protein
Lu, Z.; Gu, Y.; Cao, J.; Zhang, X.; Gao, H.; Wang, Y.; Wang, J.; Zhang, J.; Shen, G.; Jiang, X.; Yang, J.; Zheng, X.; Xu, J.; Zhang, C. C.; Lan, F.; Qu, D.; Zhao, Y.; Xu, G.; Xie, Y.; Luo, M.
10.1101/2020.09.09.287508 — microbiology — Posted on 2020-09-09
3085 Xpert MTB/XDR: A ten-color reflex assay suitable for point of care settings to detect isoniazid-, fluoroquinolone-, and second line injectable drug-resistance directly from Mycobacterium tuberculosis positive sputum.
Cao, Y.; Parmar, H.; Gaur, R.; Raghunath, S.; Lieu, D.; Via, N.; Battagalia, S.; Cirillo, D. M.; Denkinger, C.; Georghiou, S. B.; Kwiatkowski, R.; Persing, D.; Alland, D.; Chakravorty, S.
10.1101/2020.09.08.288787 — microbiology — Posted on 2020-09-09
3087 Transcriptomic dysregulations associated with SARS-CoV-2 infection in human nasopharyngeal and peripheral blood mononuclear cells
Melo, C. V. B.; Bhuiyan, M. A.; Gatua, W. N.; Kanyerezi, S.; Uzairue, L.; Abechi, P.; Kumar, K.; Rahmat, J.; Giwa, A.; Mwandira, G.; Olamilekan, A. M.; George, T. E.; Adejinmi, O. J.; Ibironke, M. A.; Rotimi, O. D.; Abo-Elenein, D. A. M. A.; Abubakar, R. A.; Usman, M.; Adewunmi, I.; Akinpelu, O.; Emmanuel, O.; Reang, K.; Olalekan, A.; Carl, S. H.
10.1101/2020.09.09.289850 — immunology — Posted on 2020-09-09
3088 Enhanced SARS-CoV-2 Neutralization by Secretory IgA in vitro
Wang, Z.; Lorenzi, J. C. C.; Muecksch, F.; Finkin, S.; Viant, C.; Gaebler, C.; Cipolla, M.; Hoffman, H.-H.; Oliveira, T. Y.; Oren, D. A.; Ramos, V.; Nogueira, L.; Michailidis, E.; Robbiani, D. F.; Gazumyan, A.; Rice, C. M.; Hatziioannou, T.; Bieniasz, P. D.; Caskey, M.; Nussenzweig, M. C.
10.1101/2020.09.09.288555 — immunology — Posted on 2020-09-09
3089 B Cell Division Capacity in Germinal Centers Depends on Myc Transcript Stabilization Through m6A mRNA Methylation and IGF2BP3 Functions
Grenov, A. C.; Moss, L.; Edelheit, S.; Cordiner, R.; Schmiedel, D.; Biram, A.; Hanna, J. H.; Heick Jensen, T.; Schwartz, S.; Shulman, Z.
10.1101/2020.09.08.287433 — immunology — Posted on 2020-09-09
3090 Small molecules inhibit SARS-COV-2 induced aberrant inflammation and viral replication in mice by targeting S100A8/A9-TLR4 axis
Guo, Q.; Zhao, Y.; Li, J.; Liu, J.; Qin, C.; Wang, X.; You, F.; Guo, X.; Zhang, Z.; Cao, L.; Luo, Y.; Wang, X.; Wei, X.; Chen, L.; Bao, L.; Deng, W.; Zhu, H.; Gao, R.
10.1101/2020.09.09.288704 — immunology — Posted on 2020-09-09
3094 Longitudinal cerebrospinal fluid proteome profiling of acute and sustained antidepressant-like effects of (2R,6R)-hydroxynorketamine (HNK) reveals involvement of glucocorticoid receptor signaling
Herzog, D. P.; Perumal, N.; Manicam, C.; Treccani, G.; Nadig, J.; Rossmanith, M.; Engelmann, J.; Jene, T.; Hasch, A.; van der Kooij, M. A.; Lieb, K.; Gassen, N. C.; Grus, F. H.; Mueller, M. B.
10.1101/2020.09.03.280834 — neuroscience — Posted on 2020-09-09
3097 Multimodal phenotypic axes of Parkinson's disease
Markello, R. D.; Shafiei, G.; Tremblay, C.; Postuma, R. B.; Dagher, A.; Misic, B.
10.1101/2020.03.05.979526 — neuroscience — Posted on 2020-09-09
3106 Testosterone enhances GLP-1 efficacy at the plasma membrane and endosomes to augment insulin secretion in male pancreatic β cells
Xu, W.; Ashford, F.; Bitsi, S.; Schiffer, L.; Qadir, F.; Arlt, W.; Tomas, A.; Hodson, D.; Mauvais-Jarvis, F.
10.1101/2020.05.12.081588 — physiology — Posted on 2020-09-09
3107 The Lonidamine Derivative H2-Gamendazole Reduces Cyst Formation in Polycystic Kidney Disease
Sundar, S. V.; Zhou, X.; Magenheimer, B. S.; Reif, G. A.; Wallace, D. P.; Georg, G. I.; Jakkaraj, S. R.; Tash, J. S.; Yu, A.; Li, X.; Calvet, J. P.
10.1101/2020.09.09.258160 — pharmacology and toxicology — Posted on 2020-09-09
3109 Near-Physiological-Temperature Serial Femtosecond X-ray Crystallography Reveals Novel Conformations of SARS-CoV-2 Main Protease Active Site for Improved Drug Repurposing
Durdagi, S.; Dag, C.; Dogan, B.; Yigin, M.; Avsar, T.; Buyukdag, C.; Erol, I.; Ertem, F. B.; Calis, S.; Yildirim, G.; Orhan, M.; Guven, O.; Aksoydan, B.; Destan, E.; Sahin, K.; Besler, S. O.; Oktay, L.; Shafiei, A.; Tolu, I.; Ayan, E.; Yuksel, B.; Peksen, A. B.; Gocenler, O.; Yucel, A. D.; Can, O.; Ozabrahamyan, S.; Olkan, A.; Erdemoglu, E.; Aksit, F.; Tanisali, G. H.; Yefanov, O. M.; Barty, A.; Tolstikova, A.; Ketawala, G. K.; Botha, S.; Dao, E. H.; Hayes, B.; Liang, M.; Seaberg, M. H.; Hunter, M. S.; Batyuk, A.; Mariani, V.; Su, Z.; Poitevin, F.; Yoon, C. H.; Kupitz, C. J.; Sierra, R. G.; Sn
10.1101/2020.09.09.287987 — biophysics — Posted on 2020-09-09
3110 Label-free imaging and classification of live P. falciparum
Lebel, P. M.; Dial, R.; Vemuri, V. N. P.; Garcia, V. E.; DeRisi, J.; Gomez-Sjoberg, R.
10.1101/2020.09.08.285346 — biophysics — Posted on 2020-09-09
3111 Rapid Assessment of T-Cell Receptor Specificity of the Immune Repertoire
Lin, X.; George, J. T.; Schafer, N. P.; Ng Chau, K.; Clementi, C.; Onuchic, J. N.; Levine, H.
10.1101/2020.04.06.028415 — biophysics — Posted on 2020-09-09
3112 Potential impact on coagulopathy of gene variants of coagulation related proteins that interact with SARS-CoV-2
Holcomb, D.; Alexaki, A.; Hernandez, N.; Laurie, K.; Kames, J.; Hamasaki-Katagiri, N.; Komar, A. A.; DiCuccio, M.; Kimchi-Sarfaty, C.
10.1101/2020.09.08.272328 — bioinformatics — Posted on 2020-09-09
3116 Organoid-in-a-column coupled on-line with liquid chromatography-mass spectrometry
Kogler, S.; Harrison, S.; Skottvoll, F. S.; Aizenshtadt, A.; Abadpour, S.; Krauss, S.; Scholz, H.; Sullivan, G.; Lundanes, E.; Wilson, S. R.
10.1101/2020.09.08.282756 — bioengineering — Posted on 2020-09-09
3119 Initial insights into the genetic epidemiology of SARS-CoV-2 isolates from Kerala suggest local spread from limited introductions
Radhakrishnan, C.; Divakar, M. K.; Jain, A.; Viswanathan, P.; Bhoyar, R. C.; Jolly, B.; Imran, M.; Sharma, D.; Rophina, M.; Ranjan, G.; Jose, B. P.; Raman, R. V.; Kesavan, T. N.; George, K.; Mathew, S.; Poovullathil, J. K.; Govindan, S. K. K.; Nair, P. R.; Vadekkandiyil, S.; Gladson, V.; Mohan, M.; Parambath, F. C.; Mangla, M.; Shamnath, A.; Sivasubbu, S.; Scaria, V.
10.1101/2020.09.09.289892 — genomics — Posted on 2020-09-09
3120 Individual differences in honey bee (Apis mellifera) behavior enabled by plasticity in brain gene regulatory networks
Jones, B. M.; Rao, V. D.; Gernat, T.; Jagla, T.; Cash-Ahmed, A.; Rubin, B. E.; Comi, T. J.; Bhogale, S.; Husain, S. S.; Blatti, C.; Middendorf, M.; Sinha, S.; Chandrasekaran, S.; Robinson, G. E.
10.1101/2020.09.09.289272 — genomics — Posted on 2020-09-09
3122 Hedgehog signaling activates a heterochronic gene regulatory network to control differentiation timing across lineages
Rowton, M.; Perez-Cervantes, C.; Rydeen, A.; Hur, S.; Jacobs-Li, J.; Deng, N.; Lu, E.; Guzzetta, A.; Steimle, J. D.; Hoffmann, A. D.; Lazarevic, S.; Yang, X. H.; Kim, C.; Yu, S.; Eckart, H.; Iddir, S.; Koska, M.; Hanson, E.; Chan, S. S.-K.; Garry, D. J.; Kyba, M.; Basu, A.; Ikegami, K.; Pott, S.; Moskowitz, I. P.
10.1101/270751 — developmental biology — Posted on 2020-09-09
3123 Effects of individual base-pairs on in vivo target search and destruction kinetics of small RNA
Poddar, A.; Azam, M. S.; Kayikcioglu, T.; Bobrovskyy, M.; Zhang, J.; Ma, X.; Labhsetwar, P.; Fei, J.; Singh, D.; Luthey-Schulten, Z.; Vanderpool, C. K.; Ha, T.
10.1101/2020.07.24.215095 — molecular biology — Posted on 2020-09-09
3124 An ex vivo model of Toxoplasma recrudescence
Goerner, A. L.; Vizcarra, E. A.; Hong, D. D.; Bergersen, K. V.; Alvarez, C. A.; Talavera, M. A.; Wilson, E. H.; White, M. W.
10.1101/2020.05.18.101931 — microbiology — Posted on 2020-09-09
3125 What the odor is not: Estimation by elimination
Singh, V.; Tchernookov, M.; Balasubramanian, V.
10.1101/568626 — neuroscience — Posted on 2020-09-09
3127 Towards robust and replicable sex differences in the intrinsic brain function of autism
Floris, D. L.; Filho, J. O. A.; Lai, M.-C.; Giavasis, S.; Oldehinkel, M.; Mennes, M.; Charman, T.; Tillmann, J.; Dumas, G.; Ecker, C.; Dell'Acqua, F.; Banaschewski, T.; Moessnang, C.; Baron-Cohen, S.; Durston, S.; Loth, E.; Murphy, D. G.; Buitelaar, J. K.; Beckmann, C.; Milham, M.; Di Martino, A.
10.1101/2020.06.09.142471 — neuroscience — Posted on 2020-09-09
3129 Live cell PNA labelling enables erasable fluorescence imaging of membrane proteins
Gavins, G.; Groeger, K.; Bartoscheck, M. D.; Wolf, P.; Beck-Sickinger, A. G.; Bultmann, S.; Seitz, O.
10.1101/2020.09.09.286310 — biophysics — Posted on 2020-09-09
3130 Relative matching using low coverage sequencing
Petter, E.; Schweiger, R.; Shahino, B.; Shor, T.; Aker, M.; Almog, L.; Weissglas-Volkov, D.; Naveh, Y.; Navon, O.; Carmi, S.; Li, J. H.; Berisa, T.; Pickrell, J. K.; Erlich, Y.
10.1101/2020.09.09.289322 — bioinformatics — Posted on 2020-09-09
3132 Bimodality of gene expression in cancer patient tumors as interpretable biomarkers for drug sensitivity
Ba-alawi, W.; Nair, S. K.; Li, B.; Mammoliti, A.; Smirnov, P.; Mer, A. S.; Penn, L.; Haibe-Kains, B.
10.1101/2020.09.08.288688 — cancer biology — Posted on 2020-09-09
3139 Computational pharmacogenomics screen identifies synergistic statin-compound combinations as anti-breast cancer therapies
van Leeuwen, J. E.; Ba-Alawi, W.; Branchard, E.; Longo, J.; Silvester, J.; Cescon, D. W.; Haibe-Kains, B.; Penn, L.; Gendoo, D.
10.1101/2020.09.07.286922 — cancer biology — Posted on 2020-09-09
3145 Nutrient Export and Periphyton Biomass in a Stream-Lake Basin from the Patagonian Andean Region
Sosnovsky, A.; Lallement, M. E.; Rechencq, M.; Fernandez, M. V.; Zattara, E. E.; Feijoo, C. S.
10.1101/2020.09.07.284893 — ecology — Posted on 2020-09-09
3147 Automated detection of Hainan gibbon calls for passive acoustic monitoring
Dufourq, E.; Durbach, I.; Hansford, J. P.; Hoepfner, A.; Ma, H.; Bryant, J. V.; Stender, C. S.; Li, W.; Liu, Z.; Chen, Q.; Zhou, Z.; Turvey, S. T.
10.1101/2020.09.07.285502 — ecology — Posted on 2020-09-09
3151 Retinal circuits driving a non-image forming visual behavior
Beier, C.; Bocchero, U.; Zhang, Z.; Jin, N.; Massey, S.; Ribelayga, C. P.; Martemyanov, K.; Hattar, S.; Pahlberg, J.
10.1101/2020.09.08.288373 — neuroscience — Posted on 2020-09-09
3152 A new model of spinal cord injury by cryoapplication:Morphodynamics of histological changes of the spinal cord lesion
Telegin, G. B.; Minakov, A. N.; Chernov, A. S.; Kazakov, V. A.; Kalabina, E. A.; Belogurov, A. A.; Konovalov, N. A.; Gabibov, A. G.
10.1101/2020.09.09.289025 — neuroscience — Posted on 2020-09-09
3156 Single-dose ethanol intoxication causes acute and lasting neuronal changes in the brain
Knabbe, J.; Protzmann, J.; Schneider, N.; Dannehl, D.; Berger, M.; Wei, S.; Strahle, C.; Jaiswal, A.; Lugani, S.; Zheng, H.; Krueger, M.; Rohr, K.; Spanagel, R.; Scholz, H.; Bilbao, A.; Engelhardt, M.; Cambridge, S.
10.1101/2020.09.09.289256 — neuroscience — Posted on 2020-09-09
3159 Optogenetic activation of CA1 pyramidal neurons in vivo induces hypersynchronous and low voltage fast seizures
Huynh, T. D.; Ashraf, O.; Craig, H.; Larmeu, L.; Barker, B.; Stepheson, C.; Murcia, D.; Howard, B.; Sun, H.
10.1101/2020.09.08.288605 — neuroscience — Posted on 2020-09-09
3160 Visual QC Protocol for FreeSurfer Cortical Parcellations from Anatomical MRI
Raamana, P. R.; Theyers, A.; Selliah, T.; Bhati, P.; Arnott, S. R.; Hassel, S.; Scott, C. J. M.; Harris, J.; Zamyadi, M.; Lam, R. W.; Milev, R.; Mueller, D. J.; Rotzinger, S.; Frey, B. N.; Kennedy, S. H.; Black, S. E.; Lang, A.; Masellis, M.; Symons, S.; Bartha, R.; MacQueen, G. M.; CANBIND Investigator Team, ; ONDRI Study Group, ; Strother, S. C.
10.1101/2020.09.07.286807 — neuroscience — Posted on 2020-09-09
3164 Controlling the flow of interruption in working memory
Hakim, N.; Feldmann-Wustefeld, T.; Awh, E.; Vogel, E. K.
10.1101/2020.09.08.288027 — neuroscience — Posted on 2020-09-09
3165 Newly regenerated axons through a cell-containing biomaterial scaffold promote reorganization of spinal circuitry and restoration of motor functions with epidural electrical stimulation.
Siddiqui, A. M.; Islam, R.; Cuellar, C. A.; Silvernail, J. L.; Knudsen, B.; Curley, D. E.; Strickland, T.; Manske, E.; T Suwan, P.; Latypov, T.; Akhmetov, N.; Zhang, S.; Summer, P.; Nesbitt, J. J.; Chen, B. K.; Grahn, P. J.; Madigan, N. N.; Yaszemski, M. J.; Windebank, A.; Lavrov, I.
10.1101/2020.09.09.288100 — neuroscience — Posted on 2020-09-09
3166 Genome-wide Chromatin Accessibility is Restricted by ANP32E
Murphy, K. E.; Meng, F. W.; Makowski, C. E.; Murphy, P. J.
10.1101/2020.09.08.288241 — genetics — Posted on 2020-09-09
3171 Cofilin1 oxidation links oxidative distress to mitochondrial demise and neuronal cell death
Hoffmann, L.; Waclawczyk, M. S.; Hanschmann, E.-M.; Gellert, M.; Rust, M. B.; Culmsee, C.
10.1101/2020.09.09.289710 — neuroscience — Posted on 2020-09-09
3172 ErbB dysregulation impairs cognition via myelination-dependent and -independent oligodendropathy
Hu, X.; Xiao, G.; He, L.; Zhu, Q.; Niu, X.; Li, H.; Xu, Q.; Wei, Z.; Huang, H.; Luan, Y.; Qiu, M.; Tanaka, K. F.; Shen, Y.; Tao, Y.
10.1101/2020.09.09.289223 — neuroscience — Posted on 2020-09-09
3174 Overconfidence in visual perception in Parkinson's disease
Halperin, O.; Karni, R.; Israeli-Korn, S.; Hassin-Baer, S.; Zaidel, A.
10.1101/2020.09.09.289082 — neuroscience — Posted on 2020-09-09
3180 Brain volumetric changes in the general population following the COVID-19 outbreak and lockdown
Salomon, T.; Cohem, A.; Ben-Zvi, G.; Gera, R.; Oren, S.; Roll, D.; Rozic, G.; Saliy, A.; Tik, N.; Tsarfati, G.; Tavor, I.; Schonberg, T.; Assaf, Y.
10.1101/2020.09.08.285007 — neuroscience — Posted on 2020-09-09
3181 No evidence of impaired sensorimotor adaptation in Complex Regional Pain Syndrome
Vitterso, A. D.; Buckingham, G.; Ten Brink, A. F.; Halicka, M.; Proulx, M. J.; Bultitude, J. H.
10.1101/2020.09.08.287862 — neuroscience — Posted on 2020-09-09
3182 A P300 brain-computer interface with a reduced visual field
Kirasirova, L.; Bulanov, V.; Ossadtchi, A.; Kolsanov, A.; Pyatin, V.; Lebedev, M.
10.1101/2020.09.07.285379 — neuroscience — Posted on 2020-09-09
3192 Intestinal inflammation modulates the expression of ACE2 and TMPRSS2 and potentially overlaps with the pathogenesis of SARS-CoV-2 related disease
Suarez-Farinas, M.; Tokuyama, M.; Wei, G.; Huang, R.; Livanos, A.; Jha, D.; Levescot, A.; Irizar, H.; Kosoy, R.; Cording, S.; Wang, W.; Irizar, H.; Ungaro, R.; Di Narzo, A.; Martinez-Delgado, G.; Suprun, M.; Corley, M. J.; Stojmirovic, A.; Houten, S.; Peters, L.; Curran, M.; Brodmerkel, C.; Perrigoue, J.; Friedman, J. R.; Hao, K.; Schadt, E. E.; Zhu, J.; Ko, H. M.; Cho, J.; Dubinsky, M. C.; Sands, B. E.; Ndhlovu, L.; Cerf-Bensusan, N.; Kasarskis, A.; Colombel, J.-F.; Harpaz, N.; Argmann, C.; Mehandru, S.
10.1101/2020.05.21.109124 — immunology — Posted on 2020-09-09
3195 SARS-CoV-2 structural coverage map reveals state changes that disrupt host immunity
O'Donoghue, S. I.; Schafferhans, A.; Sikta, N.; Stolte, C.; Kaur, S.; Ho, B.; Anderson, S.; Procter, J. B.; Dallago, C.; Bordin, N.; Adcock, M.; Rost, B.
10.1101/2020.07.16.207308 — bioinformatics — Posted on 2020-09-09
3200 How Array Design Affects SNP Ascertainment Bias
Geibel, J.; Reimer, C.; Weigend, S.; Weigend, A.; Pook, T.; Simianer, H.
10.1101/833541 — genomics — Posted on 2020-09-09
3201 Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals
Stanzick, K. J.; Li, Y.; Gorski, M.; Wuttke, M.; Pattaro, C.; Koettgen, A.; Stark, K. J.; Heid, I. M.; Winkler, T. W.
10.1101/2020.09.04.283713 — genetics — Posted on 2020-09-09
3202 Polygenic adaptation of rosette growth in Arabidopsis thaliana populations
Wieters, B.; Steige, K.; He, F.; Koch, E.; Ramos-Onsins, S.; Gu, H. Y.; Guo, Y.; Sunyaev, S.; de Meaux, J.
10.1101/2020.03.31.018341 — evolutionary biology — Posted on 2020-09-09
3203 Migration without interbreeding: evolutionary history of a highly selfing Mediterranean grass inferred from whole genomes
Stritt, C.; Gimmi, E. L.; Wyler, M.; Bakali, A. H.; Skalska, A.; Hasterok, R.; Mur, L. A. J.; Pecchioni, N.; Roulin, A. C.
10.1101/2020.09.03.280842 — evolutionary biology — Posted on 2020-09-09
3204 Assessing the reliability of species distribution projections in climate change research
Santini, L.; Benitez-Lopez, A.; Maiorano, L.; Cengic, M.; Huijbregts, M. A. J.
10.1101/2020.06.10.143917 — ecology — Posted on 2020-09-09
3206 Rapid Evolution of Plastic-degrading Enzymes Prevalent in the Global Ocean
Alam, I.; Gasol, J. M.; Arold, S. T.; Gojobori, T.; Kamau, A. A.; Aalismail, N.; Martin, C.; Momin, A. A.; Acinas, S. G.; Guzman-Vega, F. J.; Agusti, S. R.; Jamil, T.; Duarte, C. M.
10.1101/2020.09.07.285692 — evolutionary biology — Posted on 2020-09-09
3207 Inheritance of associative memories in C. elegans ‎nematodes
Deshe, N.; Eliezer, Y.; Hoch, L.; Itskovits, E.; Ben-Ezra, S.; Zaslaver, A.
10.1101/2020.09.08.287318 — neuroscience — Posted on 2020-09-09
3208 Porcine model elucidates function of p53 isoform in carcinogenesis
Niu, G.; Hellmuth, I.; Flisikowska, T.; Pausch, H.; Rieblinger, B.; Carrapeiro, A.; Schade, B.; Boehm, B.; Kappe, E.; Fischer, K.; Klinger, B.; Steiger, K.; Saur, D.; Bourdon, J.-C.; Burgkart, R.; Kind, A.; Schnieke, A.; Flisikowski, K.
10.1101/2020.09.07.286005 — cancer biology — Posted on 2020-09-08
3211 Seasonal and long-term consequences of esca on grapevine stem xylem integrity
Bortolami, G.; Farolfi, E.; Badel, E.; Burlett, R.; Cochard, H.; Ferrer, N.; King, A.; Lamarque, L. J.; Lecomte, P.; Marchesseau Marchal, M.; Pouzoulet, J.; Torres-Ruiz, J. M.; Trueba, S.; Delzon, S.; Gambetta, G. A.; Delmas, C. E. L.
10.1101/2020.09.07.282582 — plant biology — Posted on 2020-09-08
3215 Neuroinvasion of SARS-CoV-2 in human and mouse brain
Song, E.; Zhang, C.; Israelow, B.; Lu-Culligan, A.; Sprado, A.; Skriabine, S.; Lu, P.; Weizman, O.-E.; Liu, F.; Dai, Y.; Szigeti-Buck, K.; Yasumoto, Y.; Wang, G.; Castaldi, C.; Heltke, J.; Ng, E.; Wheeler, J.; Alfajaro, M. M.; LEVAVASSEUR, E.; Fontes, B.; Ravindra, N.; van Dijk, D.; Mane, S.; Gunel, M.; Ring, A.; Kazmi, S.; Zhang, K.; Wilen, C. B.; Horvath, T.; Plu, I.; Haik, s.; thomas, j.-l.; LOUVI, A.; Farhadian, S.; Huttner, A.; seilhean, d.; RENIER, N.; Bilguvar, K.; Iwasaki, A.
10.1101/2020.06.25.169946 — microbiology — Posted on 2020-09-08
3216 Species-specific differences in antagonism of APOBEC3 proteins by HIV-2 and SIVsmm Vif proteins
Nchioua, R.; Kmiec, D.; Gaba, A.; Stürzel, C. M.; Follack, T.; Patrick, S.; Kirmaier, A.; Johnson, W. E.; Hahn, B. H.; Chelico, L.; Kirchhoff, F.
10.1101/2020.09.08.287177 — immunology — Posted on 2020-09-08
3221 An analysis of genetic diversity actions, indicators and targets in 114 National Reports to the Convention on Biological Diversity
Hoban, S.; Campbell, C.; da Silva, J.; Ekblom, R.; Funk, W. C.; Garner, B.; Godoy, J. A.; Kershaw, F.; MacDonald, A.; Mergeay, J.; Minter, M.; O'Brien, D.; Paz-Vinas, I.; Pearson, S. K.; Perez-Espona, S.; Potter, K.; Russo, I.-R.; Segelbacher, G.; Vernesi, C.; Hunter, M. E.
10.1101/2020.08.28.254672 — scientific communication and education — Posted on 2020-09-08
3226 The Shh/Gli3 gene regulatory network precedes the origin of paired fins and reveals the deep homology between distal fins and digits.
Letelier, J.; Naranjo, S.; Sospedra, I.; Lopez-Rios, J.; Martinez-Morales, J. R.; Shubin, N.; Gomez-Skarmeta, J. L.
10.1101/2020.09.08.287532 — evolutionary biology — Posted on 2020-09-08
3228 Structure and dynamics of the quaternary hunchback mRNA translation repression complex
Macosek, J.; Simon, B.; Linse, J.-B.; Winter, S.; Foot, J.; Perez, K.; Rettel, M.; Ivanovic, M. T.; Masiewicz, P.; Murciano, B.; Savitski, M. M.; Hub, J. S.; Gabel, F.; Hennig, J.
10.1101/2020.09.08.287060 — molecular biology — Posted on 2020-09-08
3229 The N-terminus of varicella-zoster virus glycoprotein B has a functional role in fusion.
Oliver, S. L.; Xing, Y.; Chen, D.-H.; Roh, S. H.; Pintilie, G. D.; Bushnell, D. A.; Sommer, M. H.; Yang, E.; Carfi, A.; Chiu, W.; Arvin, A. M.
10.1101/2020.09.08.269191 — microbiology — Posted on 2020-09-08
3231 Dysregulation of adipose ILC2 underlies thermogenic failure in aging
Goldberg, E. L.; Shchukina, I.; Youm, Y.-H.; Camell, C. D.; Dlugos, T.; Artyomov, M.; Dixit, V. D.
10.1101/2020.09.08.288431 — immunology — Posted on 2020-09-08
3232 miR-424(322) is a molecular switch controlling pro-inflammatory vs anti-inflammatory skin DC subset differentiation by modulating TGF-β signaling
Zyulina, V.; Yan, K.-K.; Ju, B.; Passegger, C.; Tam-Amersdorfer, C.; Pan, Q.; Sconocchia, T.; Pollack, C.; Shaner, B.; Zebisch, A.; Easton, J.; Yu, J.; Silva, J.; Strobl, H.
10.1101/2020.09.07.285627 — immunology — Posted on 2020-09-08
3235 A dopamine gradient controls access to distributed working memory in monkey cortex
Froudist-Walsh, S.; Bliss, D. P.; Ding, X.; Jankovic-Rapan, L.; Niu, M.; Knoblauch, K.; Zilles, K.; Kennedy, H.; Palomero-Gallagher, N.; Wang, X.-J.
10.1101/2020.09.07.286500 — neuroscience — Posted on 2020-09-08
3236 Highly enriched hiPSC-derived midbrain dopaminergic neurons robustly models Parkinson's disease.
Virdi, G. S.; Choi, M. L.; Yao, Z.; Evans, J. R.; Athauda, D.; Melandri, D.; Sylantyev, S.; Abramov, A. Y.; Patani, R.; Gandhi, S.
10.1101/2020.09.08.287797 — neuroscience — Posted on 2020-09-08
3237 An evolutionarily acquired microRNA shapes development of mammalian cortical projections
Diaz, J. L.; Siththanandan, V.; Lu, V.; Gonzalez-Nava, N.; Pasquina, L.; MacDonald, J.; Woodworth, M. B.; Ozkan, A.; Nair, R.; He, Z.; Sahni, V.; Sarnow, P.; Palmer, T. D.; Macklis, J.; Tharin, S.
10.1101/2020.09.08.286955 — neuroscience — Posted on 2020-09-08
3238 Dynamics of episodic and continuous rhythmic activities from a developing central pattern generator
Sharples, S. A.; Vargas, A.; Lognon, A. P.; Young, L.; Shonak, A.; Cymbalyuk, G. S.; Whelan, P. J.
10.1101/2020.09.08.288266 — neuroscience — Posted on 2020-09-08
3242 High spatial resolution global ocean metagenomes from Bio-GO-SHIP repeat hydrography transects
Larkin, A. A.; Garcia, C. A.; Brock, M. L.; Lee, J. A.; Garcia, N.; Ustick, L. J.; Barbero, L.; Carter, B. R.; Sonnerup, R. E.; Talley, L.; Tarran, G. A.; Volkov, D. L.; Martiny, A. C.
10.1101/2020.09.06.285056 — genomics — Posted on 2020-09-08
3243 The structure, function, and evolution of a complete human chromosome 8
Logsdon, G. A.; Vollger, M. R.; Hsieh, P.; Mao, Y.; Liskovykh, M. A.; Koren, S.; Nurk, S.; Mercuri, L.; Dishuck, P. C.; Rhie, A.; de Lima, L. G.; Porubsky, D.; Bzikadze, A. V.; Kremitzki, M.; Graves-Lindsay, T. A.; Jain, C.; Hoekzema, K.; Murali, S. C.; Munson, K. M.; Baker, C.; Sorenson, M.; Lewis, A. M.; Surti, U.; Gerton, J. L.; Larionov, V.; Ventura, M.; Miga, K. H.; Phillippy, A. M.; Eichler, E. E.
10.1101/2020.09.08.285395 — genomics — Posted on 2020-09-08
3245 Identification of colonisation and virulence determinants of Streptococcus pneumoniae via experimental evolution in mouse infection models
Green, A. E.; Howarth, D.; Chaguza, C.; Echlin, H.; Langendonk, R. F.; Munro, C.; Barton, T. E.; Hinton, J. C.; Bentley, S. D.; Rosch, J.; Neill, D. R.
10.1101/2020.09.08.287698 — microbiology — Posted on 2020-09-08
3248 Multivariate pattern analysis of brain structure predicts functional outcome after auditory-based cognitive training interventions
Kambeitz-Ilankovic, L.; Vinogradov, S.; Wenzel, J.; Fisher, M.; Haas, S.; Betz, L.; Penzel, N.; Nagarajan, S.; Koutsouleris, N.; Subramaniam, K.
10.1101/2020.09.06.283481 — neuroscience — Posted on 2020-09-08
3250 Phloem loading via the abaxial bundle sheath cells in maize leaves
Bezrutczyk, M.; Zoellner, N.; Kruse, C. P. S.; Hartwig, T.; Lautwein, T.; Koehrer, K.-E.; Frommer, W. B.; Kim, J.-Y.
10.1101/2020.09.06.284943 — plant biology — Posted on 2020-09-08
3252 Short-term exposure to intermittent hypoxia leads to changes in gene expression seen in chronic pulmonary disease
Wu, G.; Lee, Y. Y.; Gulla, E. M.; Potter, A.; Kitzmiller, J.; Ruben, M. D.; Salomonis, N.; Whitsett, J. A.; Francey, L. J.; Hogenesch, J. B.; Smith, D. F.
10.1101/2020.03.06.981241 — pathology — Posted on 2020-09-08
3253 TAZ-CAMTA1 and YAP-TFE3 modulate the basal TAZ/YAP transcriptional program by recruiting the ATAC histone acetyltransferase complex
Merritt, N.; Garcia, K.; Rajendran, D.; Lin, Z.-Y.; Zhang, X.; Mitchell, K.; Borcherding, N.; Fullenkamp, C.; Chimenti, M.; Gingras, A.-C.; Harvey, K.; Tanas, M. R.
10.1101/2020.09.07.286633 — cancer biology — Posted on 2020-09-08
3254 The pleiotropic effects of the MNK1/2-eIF4E axis support immune suppression and metastasis in a model of postpartum breast cancer.
Guo, Q.; Bartish, M.; Goncalves, C.; Huang, F.; Krisna, S. S.; Preston, S.; Emond, A.; Li, V. Z.; Duerr, C.; Gui, Y.; Cleret-Buhot, A.; Thebault, P.; Lefrere, H.; Lenaerts, L.; Plourde, D.; Su, J.; Mindt, B. C.; Hewgill, S.; Cotechini, T.; Hindmarch, C.; Yang, W.; Khoury, E.; Zhan, Y.; Narykina, V.; Wei, Y.; Floris, G.; Basik, M.; Amant, F.; Quail, D.; Lapointe, R.; Fritz, J.; del Rincon, S. V.; Miller, W. H.
10.1101/2020.09.07.286815 — cancer biology — Posted on 2020-09-08
3259 Decoding the Protein Composition of Whole Nucleosomes with Nuc-MS
Schachner, L. F.; Jooss, K.; Morgan, M. A.; Piunti, A.; Meiners, M. J.; Lee, A.; Kafader, J. O.; Iwanaszko, M.; Cheek, M. A.; Burg, J. M.; Howard, S. A.; Keogh, M.-C.; Shilatifard, A.; Kelleher, N. L.
10.1101/2020.09.08.287656 — biochemistry — Posted on 2020-09-08
3261 A metabolic life table exemplified by sockeye salmon
Burger, J. R.; Hou, C.; Hall, C. A. S.; Brown, J. H.
10.1101/2020.03.13.990986 — ecology — Posted on 2020-09-08
3262 Many bat species are not potential hosts of SARS-CoV and SARS-CoV-2: Evidence from ACE2 receptor usage
Yan, H.; Jiao, H.; Liu, Q.; Zhang, Z.; Wang, X.; Guo, M.; Wang, B.-J.; Lan, K.; Chen, Y.; Zhao, H.
10.1101/2020.09.08.284737 — ecology — Posted on 2020-09-08
3266 Diversity and function of microbial lipases within the mammalian gut
Hitch, T. C. A.; Masson, J. M.; Streidl, T.; Fischöder, T.; Elling, L.; Clavel, T.
10.1101/2020.09.08.287425 — microbiology — Posted on 2020-09-08
3268 Deep sea sediments associated with cold seeps are a subsurface reservoir of viral diversity
Li, Z.; Pan, D.; Wei, G.; Pi, W.; Wang, J.-H.; Peng, Y.; Zhang, L.; Wang, Y.; Hubert, C. R. J.; Dong, X.
10.1101/2020.09.08.284018 — microbiology — Posted on 2020-09-08
3272 Bacteriophage uptake by Eukaryotic cell layers represents a major sink for phages during therapy
Bichet, M. C.; Chin, W. H.; Richards, W.; Lin, Y.-W.; Avellaneda-Franco, L.; Hernandez, C. A.; Oddo, A.; Chernyavskiy, O.; Hilsenstein, V.; Neild, A.; Li, J. C.; Voelcker, N. H.; Patwa, R.; Barr, J. J.
10.1101/2020.09.07.286716 — microbiology — Posted on 2020-09-08
3275 Stochastic asymmetric repartition of lytic machinery in dividing human CD8+ T cells generates heterogeneous killing behavior
Lafouresse, F.; Jugele, R.; Mueller, S.; Doineau, M.; Duplan-Eche, V.; Espinosa, E.; Puissegur, M.-P.; Gadat, S.; Valitutti, S.
10.1101/2020.09.08.287029 — immunology — Posted on 2020-09-08
3276 Ly6C defines a subset of memory-like CD27+ γδ T cells with inducible cancer-killing function
Wiesheu, R.; Edwards, S. C.; Hedley, A.; Kirschner, K.; Tosolini, M.; Fournie, J.-J.; Kilbey, A.; Remak, S.-J.; Miller, C.; Blyth, K.; Coffelt, S. B.
10.1101/2020.09.08.287854 — immunology — Posted on 2020-09-08
3280 Relationship between impulsivity, uncontrolled eating and body mass index: a hierarchical model
Garcia-Garcia, I.; Neseliler, S.; Morys, F.; Dadar, M.; Yau, Y. H.; Scala, S. G.; Zeighami, Y.; Sun, N.; Collins, D. L.; Vainik, U.; Dagher, A.
10.1101/348821 — neuroscience — Posted on 2020-09-08
3281 Bundle-specific associations between white matter microstructure and Aβ and tau pathology at their connecting cortical endpoints in older adults at risk of Alzheimer's disease
Pichet Binette, A.; Theaud, G.; Rheault, F.; Roy, M.; Collins, D. L.; Breitner, J. C. S.; Poirier, J.; Descoteaux, M.; Villeneuve, S.; PREVENT-AD Research Group,
10.1101/2020.08.27.266551 — neuroscience — Posted on 2020-09-08
3284 Recursive Convolutional Neural Networks for Epigenomics
Symeonidi, A.; Nikolaou, A.; Johannes, F.; Christlein, V.
10.1101/2020.04.02.021519 — bioinformatics — Posted on 2020-09-08
3288 Antibody-based delivery of Interleukin-9 to neovascular structures: therapeutic evaluation in cancer and arthritis
Gouyou, B.; Ongaro, T.; Cazzamalli, S.; De Luca, R.; Kerschenmeyer, A.; Valet, P.; Villa, A.; Neri, D.; Matasci, M.
10.1101/2020.08.26.268292 — bioengineering — Posted on 2020-09-08
3291 Cell shape regulates subcellular organelle location to control short-term Ca2+ signal dynamics in vascular smooth muscle cells
Calizo, R. C.; Bell, M.; Ron, A.; Hu, M.; Bhattacharya, S.; Wong, N.; Janssen, W. G. M.; Perumal, G.; Pedersen, P.; Scarlata, S.; Hone, J.; Azeloglu, E. U.; Rangamani, P.; Iyengar, R.
10.1101/161950 — cell biology — Posted on 2020-09-08
3293 Histone deposition pathways determine the chromatin landscapes of H3.1 and H3.3 K27M oncohistones
Sarthy, J. F.; Meers, M. P.; Janssens, D.; Henikoff, J. G.; Morris, S.; Biery, M.; Feldman, H.; Paddison, P. J.; Lockwood, C. M.; Vitanza, N.; Olson, J. M.; Ahmad, K.; Henikoff, S.
10.1101/2020.05.18.101709 — molecular biology — Posted on 2020-09-08
3296 HIV antiretrovirals have differential effects on viability and function in human iPSC-derived neurons and neural precursor cells
Smith, A. S.; Ankam, S.; Farhy, C.; Basa, R. C. B.; Gordon, K. L.; Terskikh, A. V.; Jordan-Sciutto, K. L.; Price, J. H.; McDonough, P. M.
10.1101/2020.09.05.284422 — neuroscience — Posted on 2020-09-08
3301 Polygenic Risk Scores for Kidney Function to the Circulating Proteome, and Incident Kidney Diseases: the Atherosclerosis Risk in Communities Study
Yu, Z.; Jin, J.; Tin, A.; Kottgen, A.; Yu, B.; Chen, J.; Surapaneni, A.; Zhou, L.; Ballantyne, C. M.; Hoogeveen, R. C.; Arking, D. E.; Chatterjee, N.; Grams, M. E.; Coresh, J.
10.1101/2020.09.05.284265 — genetics — Posted on 2020-09-08
3305 Real Time and Delayed Effects of Subcortical Low Intensity Focused Ultrasound
Cain, J. A.; Visagan, S.; Johnson, M.; Crone, J.; Blades, R.; Spivak, N.; Shattuck, D.; Monti, M. M.
10.1101/2020.09.05.283747 — neuroscience — Posted on 2020-09-08
3307 Many bat species are not potential hosts of SARS-CoV and SARS-CoV-2: Evidence from ACE2 receptor usage
Yan, H.; Jiao, H.; Liu, Q.; Zhang, Z.; Wang, X.; Guo, M.; Wang, B.-J.; Lan, K.; Chen, Y.; Zhao, H.
10.1101/2020.09.08.284737 — ecology — Posted on 2020-09-08
3308 Interaction of human ACE2 to membrane-bound SARS-CoV-1 and SARS-CoV-2 S glycoproteins
Anand, S. P.; Chen, Y.; Prevost, J.; Gasser, R.; Beaudoin-Bussieres, G.; Abrams, C. F.; Pazgier, M.; Finzi, A.
10.1101/2020.09.07.286567 — microbiology — Posted on 2020-09-08
3310 Antibody binding to SARS-CoV-2 S glycoprotein correlates with, but does not predict neutralization
Ding, S.; Laumaea, A.; Gasser, R.; Medjahed, H.; Pancera, M.; Stamatatos, L.; McGuire, A.; Bazin, R.; Finzi, A.
10.1101/2020.09.08.287482 — microbiology — Posted on 2020-09-08
3311 A prefusion SARS-CoV-2 spike RNA vaccine is highly immunogenic and prevents lung infection in non-human primates
Vogel, A.; Kanevsky, I.; Che, Y.; Swanson, K.; Muik, A.; Vormehr, M.; Kranz, L.; Walzer, K.; Hein, S.; Gueler, A.; Loschko, J.; Maddur, M.; Tompkins, K.; Cole, J.; Lui, B. G.; Ziegenhals, T.; Plaschke, A.; Eisel, D.; Dany, S.; Fesser, S.; Erbar, S.; Bates, f.; Schneider, D.; Jesionek, B.; Saenger, B.; Wallisch, A.-K.; Feuchter, Y.; Junginger, H.; Krumm, S.; Heinen, A.; Adams-Quack, P.; Schlereth, J.; Kroener, C.; Hall-Ursone, S.; Brasky, K.; Griffor, M. C.; Han, S.; Lees, J.; Mashalidis, E.; Sahasrabudhe, P.; Tan, C.; Pavliakova, D.; Singh, G.; Fontes-Garfias, C.; Pride, M.; Scully, I.; Ciolin
10.1101/2020.09.08.280818 — immunology — Posted on 2020-09-08
3312 Longitudinal high-throughput TCR repertoire profiling reveals the dynamics of T cell memory formation after mild COVID-19 infection
Minervina, A. A.; Komech, E. A.; Titov, A.; Bensouda Koraichi, M.; Rosati, E.; Mamedov, I. Z.; Franke, A.; Efimov, G. A.; Chudakov, D. M.; Mora, T.; Walczak, A. M.; Lebedev, Y. B.; Pogorelyy, M. V.
10.1101/2020.05.18.100545 — immunology — Posted on 2020-09-08
3313 Analysis of SARS-CoV-2 genomes from across Africa reveals potentially clinically relevant mutations.
Iweriebor, B. C.; Egbule, O. S.; Danso, S. O.; Akujuru, E.; Ibubeleye, V. T.; Oweredaba, C. I.; Ogharanduku, T.; Manu, A.; Longjohn, M. N.
10.1101/2020.09.08.287201 — bioinformatics — Posted on 2020-09-08
3314 UVA radiation could be a significant contributor to sunlight inactivation of SARS-CoV-2
Luzzatto-Fegiz, P.; Temprano-Coleto, F.; Peaudecerf, F. J.; Landel, J. R.; Zhu, Y.; McMurry, J. A.
10.1101/2020.09.07.286666 — biochemistry — Posted on 2020-09-08
3317 Terminal Modification, Sequence, and Length Determine Small RNA Stability in Animals
Gainetdinov, I.; Colpan, C.; Cecchini, K.; Albosta, P.; Jouravleva, K.; Vega-Badillo, J.; Lee, Y.; Ozata, D.; Zamore, P. D.
10.1101/2020.09.08.287979 — molecular biology — Posted on 2020-09-08
3318 McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation
Hajdusits, B.; Suskiewicz, M. J.; Hundt, N.; Meinhart, A.; Kurzbauer, R.; Leodolter, J.; Kukura, P.; Clausen, T.
10.1101/2020.09.08.287243 — molecular biology — Posted on 2020-09-08
3319 Fungi are colder than their surroundings
Cordero, R. J.; Mattoon, E. R.; Casadevall, A.
10.1101/2020.05.09.085969 — microbiology — Posted on 2020-09-08
3324 Reconstitution of prospermatogonial specification in vitro from human induced pluripotent stem cells
Hwang, Y. S.; Suzuki, S.; Seita, Y.; Ito, J.; Sakata, Y.; Aso, H.; Sato, K.; Hermann, B. P.; Sasaki, K.
10.1101/2020.09.08.286930 — developmental biology — Posted on 2020-09-08
3325 Planarian CREB-binding protein (CBP) gene family regulates stem cell maintenance and differentiation
Fraguas, S.; Carcel, S.; Vivancos, C.; Molina, M. D.; Gines, J.; Mazariegos, J.; Sekaran, T.; Bartscherer, K.; Romero, R.; Cebria, F.
10.1101/2020.09.08.287045 — developmental biology — Posted on 2020-09-08
3326 CTCF knockout in zebrafish induces alterations in regulatory landscapes and developmental gene expression
Franke, M.; De la Calle-Mustienes, E.; Neto, A.; Acemel, R. D.; Tena, J. J.; Santos-Pereira, J. M.; Gomez-Skarmeta, J. L.
10.1101/2020.09.08.282707 — developmental biology — Posted on 2020-09-08
3327 Heterogeneous distribution of mRNAs within flight muscle fibers, and implications for function
Parekh, A.; Chakraborty, K.; Purohit, D. J.; Pasha, S. N.; Sowdhamini, R.; VijayRaghavan, K.; Chaturvedi, D.
10.1101/2020.09.07.286260 — developmental biology — Posted on 2020-09-08
3329 Is zebrafish heart regeneration complete? Lineage-restricted cardiomyocytes proliferate to pre-injury numbers but some fail to differentiate in fibrotic hearts
Bertozzi, A.; Wu, C.-C.; Nguyen, P. D.; Vasudevarao, M. D.; Mulaw, M. A.; Koopman, C. D.; de Beur, T. P.; Bakkers, J.; Weidinger, G.
10.1101/2020.09.08.277939 — developmental biology — Posted on 2020-09-08
3330 Endothelial cell invasiveness is controlled by myosin IIA-dependent inhibition of Arp2/3 activity
Figueiredo, A.; Barbacena, P.; Russo, A.; Vaccaro, S.; Ramalho, D.; Pena, A.; Lima, A. P.; Ferreira, R. R.; El-Marjou, F.; Carvalho, Y.; Vasconcelos, F. F.; Lennon-Dumenil, A.-M.; M. Vignevic, D.; Franco, C. A.
10.1101/2020.09.08.287466 — cell biology — Posted on 2020-09-08
3334 Scalable, multimodal profiling of chromatin accessibility and protein levels in single cells
Mimitou, E. P.; Lareau, C. A.; Chen, K. Y.; Zorzetto-Fernandes, A. L.; Takeshima, Y.; Luo, W.; Huang, T.-S.; Yeung, B.; Thakore, P. I.; Badger Wing, J.; Nazor, K. L.; Sakaguchi, S.; Ludwig, L. S.; Sankaran, V. G.; Regev, A.; Smibert, P.
10.1101/2020.09.08.286914 — genomics — Posted on 2020-09-08
3335 β-catenin dependent axial patterning in Cnidaria and Bilateria uses similar regulatory logic
Bagaeva, T.; Aman, A. J.; Graf, T.; Niedermoser, I.; Zimmermann, B.; Kraus, Y.; Schatka, M.; Demilly, A.; Technau, U.; Genikhovich, G.
10.1101/2020.09.08.287821 — developmental biology — Posted on 2020-09-08
3337 Multivariate GWAS of psychiatric disorders and their cardinal symptoms reveal two dimensions of cross-cutting genetic liabilities
Mallard, T. T.; Karlsson Linner, R.; Grotzinger, A. D.; Sanchez-Roige, S.; Seidlitz, J.; Okbay, A.; de Vlaming, R.; Meddens, S. F. W.; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, ; Palmer, A. A.; Davis, L. K.; Tucker-Drob, E. M.; Kendler, K.; Keller, M. C.; Koellinger, P. D.; Harden, K. P.
10.1101/603134 — genetics — Posted on 2020-09-08
3338 Vimentin intermediate filaments mediate cell shape on visco-elastic substrates
Swoger, M.; Gupta, S.; Charrier, E.; Bates, M.; Hehnly, H.; Patteson, A. E.
10.1101/2020.09.07.286237 — biophysics — Posted on 2020-09-08
3343 Epigenetic clock and methylation studies in cats
Raj, K.; Szladovits, B.; Haghani, A.; Zoller, J. A.; Li, C. Z.; Horvath, S.
10.1101/2020.09.06.284877 — developmental biology — Posted on 2020-09-08
3346 Performances of targeted RNA-sequencing for the analysis of fusion transcripts, gene mutation and expression in haematological malignancies.
Hayette, S.; Grange, B.; Valee, M.; Bardel, C.; Huet, S.; Chabane, K.; Mosnier, I.; Simonet, T.; Balsat, M.; Hieblig, M.; Tigaud, I.; Nicolini, F. E.; Mareschal, S.; Salles, G.; Sujobert, P.
10.1101/2020.09.07.285981 — genomics — Posted on 2020-09-08
3347 Dietary suppression of MHC-II expression in intestinal stem cells enhances intestinal tumorigenesis
Beyaz, S.; Roper, J.; Xifaras, M. E.; Bauer-Rowe, K. E.; Ergin, I.; Dohnalova, L.; Biton, M.; Shekar, K.; Mou, H.; Eskiocak, O.; Ozata, D. M.; Chung, C.; Papciak, K.; Almeqdadi, M.; Fein, M.; Erdemir, A.; Valle-Encinas, E.; Dogum, K.; Garipcan, A.; Meyer, H.; Fox, J. G.; Elinav, E.; Kucukural, A.; Kumar, P.; McAleer, J.; Thaiss, C. A.; Regev, A.; Orkin, S. H.; Yilmaz, O. H.
10.1101/2020.09.05.284174 — cancer biology — Posted on 2020-09-08
3349 Label-free and Multimodal Second Harmonic Generation Light Sheet Microscopy
Hanrahan, N.; Lane, S. I. R.; JOHNSON, P. B.; Bourdakos, K. N.; Brereton, C. J.; Ridley, R. A.; Davies, E. R.; Hosny, N. A.; Spickermann, G.; Forster, R.; Malcolm, G.; Davies, D. E.; Jones, M. G.; Mahajan, S.
10.1101/2020.09.07.284703 — biophysics — Posted on 2020-09-08
3351 Exploratory polarization facilitates mating partner selection in Saccharomyces cerevisiae
Clark-Cotton, M. R.; Henderson, N.; Pablo, M.; Ghose, D.; Elston, T.; Lew, D. J.
10.1101/2020.09.07.285965 — cell biology — Posted on 2020-09-07
3354 Comparative mapping of crawling-cell morphodynamics in deep learning-based feature space
Imoto, D.; Saito, N.; Nakajima, A.; Honda, G.; Ishida, M.; Sugita, T.; Ishihara, S.; Katagiri, K.; Okimura, C.; Iwadate, Y.; Sawai, S.
10.1101/2020.09.06.285411 — cell biology — Posted on 2020-09-08
3355 Single-molecule FRET monitors CLC transporter conformation and subunit independence
Cheng, R. C.; Krishnamoorti, A.; Berka, V.; Durham, R. J.; Jayaraman, V.; Maduke, M.
10.1101/2020.09.07.286831 — biophysics — Posted on 2020-09-07
3357 OpenAWSEM with Open3SPN2: a fast, flexible, and accessible framework for large-scale coarse-grained biomolecular simulations
Lu, W.; Bueno, C.; Schafer, N. P.; Moller, J.; Jin, S.; Chen, M.; Gu, X.; de Pablo, J. J.; Wolynes, P. G.
10.1101/2020.09.07.285759 — molecular biology — Posted on 2020-09-07
3358 Control of ss-glucan exposure by the endo-1,3-glucanase Eng1 in Candida albicans modulates virulence
Yang, M.; Solis, N.; Marshall, M.; Garleb, R. A.; Zhou, T.; Wang, D.; Swidergall, M.; Pearlman, E.; Filler, S.; Liu, H.
10.1101/2020.09.07.285791 — microbiology — Posted on 2020-09-07
3359 Nonlinear decoding of natural images from large-scale primate retinal ganglion recordings
Kim, Y. J.; Brackbill, N.; Batty, E.; Lee, J.; Mitelut, C.; Tong, W.; Chichilnisky, E. J.; Paninski, L.
10.1101/2020.09.07.285742 — neuroscience — Posted on 2020-09-07
3363 The structural basis of the oncogenic mutant K-Ras4B homodimers
Kosoglu, K.; Omur, M. E.; Jang, H.; Nussinov, R.; Keskin, O.; Gursoy, A.
10.1101/2020.09.07.285783 — biophysics — Posted on 2020-09-07
3366 Generating single-sex litters: development of CRISPR-Cas9 genetic tools to produce all-male offspring
Douglas, C.; Maciulyte, V.; Zohren, J.; Snell, D. M.; Ojarikre, O. A.; Ellis, P. J.; Turner, J. M. A.
10.1101/2020.09.07.285536 — genetics — Posted on 2020-09-07
3370 Proximity proteomics reveal EPH tyrosine kinase receptors' regulation of cell polarity and identify Par3 scaffold protein as a novel effector of EPH signaling
Banerjee, S. L.; Lavoie, N.; Jacquet, K.; Lessard, F.; Chartier, F. J. M.; Dionne, U.; Lavoie, J. N.; Elowe, S.; Lambert, J.-P.; Laprise, P.; Bisson, N.
10.1101/2020.09.06.285270 — molecular biology — Posted on 2020-09-07
3375 Methionine synthase supports tumor tetrahydrofolate pools
Wang, J. Z.; Ghergurovich, J. M.; Yang, L.; Rabinowitz, J. D.
10.1101/2020.09.05.284521 — cancer biology — Posted on 2020-09-07
3376 Oncogenetic Landscape Of Lymphomagenesis In Coeliac Disease
Cording, S.; Lhermitte, L.; Malamut, G.; Berrabah, S.; Trinquand, A.; Guegan, N.; Villarese, P.; Kaltenbach, S.; Meresse, B.; Khater, S.; Dussiot, M.; Bras, M.; Cheminant, M.; Tesson, B.; Bole-Feysot, C.; Bruneau, J.; Molina, T. J.; Sibon, D.; Macintyre, E.; Hermine, O.; Cellier, C.; Asnafi, V.; Cerf-Bensussan, N.
10.1101/2020.09.07.275032 — cancer biology — Posted on 2020-09-07
3377 The deacylase SIRT5 supports melanoma viability by regulating chromatin dynamics
Giblin, W.; Bringman-Rodenbarger, L.; Kumar, S.; Skinner, M. E.; Guo, A.; Mostafa, A. M.; Azar, M.; Mady, A. S. A.; Chung, C. H.; Kadambi, N.; Melong, K.-A.; Lee, H.-J.; Zhang, L.; Sajjakulnukit, P.; Trefely, S.; Varner, E. L.; Iyer, S.; Wang, M.; Wilmott, J. S.; Soyer, H. P.; Sturm, R. A.; Pritchard, A. L.; Andea, A.; Scolyer, R. A.; Stark, M. S.; Scott, D. A.; Fullen, D. R.; Bosenberg, M. W.; Chandrasekaran, S.; Nikolovska-Coleska, Z.; Verhaegen, M.; Snyder, N. W.; Rivera, M. N.; Osterman, A. L.; Lyssiotis, C. A.; Lombard, D. B.
10.1101/2020.09.07.286526 — cancer biology — Posted on 2020-09-07
3378 Metagenomics Strain Resolution on Assembly Graphs
Quince, C.; Nurk, S.; Raguideau, S.; James, R. S.; Soyer, O. S.; Summers, J. K.; Limasset, A.; Eren, A. M.; Chikhi, R.; Darling, A. E.
10.1101/2020.09.06.284828 — bioinformatics — Posted on 2020-09-07
3379 Lamin A/C functions independently from mechanical signaling during adipogenesis
Goelzer, M.; Dudakovic, A.; Olcum, M.; Sen, B.; Ozcivici, E.; Rubin, J.; van Wijnen, A. J.; Uzer, G.
10.1101/2020.09.07.279828 — bioengineering — Posted on 2020-09-07
3383 Clumpy coexistence in phytoplankton: The role of functional similarity in community assembly
Graco-Roza, C.; Segura, A. M.; Kruk, C.; Domingos, P.; Soininen, J.; Marinho, M. M.
10.1101/869966 — ecology — Posted on 2020-09-07
3384 Stretch Regulates Alveologenesis Via Mesenchymal Gαq/11-Mediated TGFβ2 Activation
Goodwin, A. T.; John, A. E.; Joseph, C.; Habgood, A.; Tatler, A. L.; Offermanns, S.; Henderson, N. C.; Jenkins, G.
10.1101/2020.09.06.284778 — developmental biology — Posted on 2020-09-07
3387 The SARS-CoV-2 multibasic cleavage site facilitates early serine protease-mediated entry into organoid-derived human airway cells
Mykytyn, A. Z.; Breugem, T. I.; Riesebosch, S.; Schipper, D.; van den Doel, P. B.; Rottier, R.; Lamers, M. M.; Haagmans, B. L.
10.1101/2020.09.07.286120 — microbiology — Posted on 2020-09-07
3399 Inferring active cis-regulatory modules to predict functional regulatory elements
Chen, X.; Neuwald, A. F.; Hilakivi-Clarke, L.; Clarke, R.; Xuan, J.
10.1101/560862 — bioinformatics — Posted on 2020-09-07
3401 Global analysis of transcription start sites in the new ovine reference genome (Oar rambouillet v1.0)
Salavati, M.; Caulton, A.; Clark, R.; Gazova, I.; Smith, T. P. L.; Worley, K. C.; Cockett, N. E.; Archibald, A. L.; Clarke, S. M.; Murdoch, B. M.; Clark, E. L.; The Ovine FAANG Project Consortium,
10.1101/2020.07.06.189480 — genomics — Posted on 2020-09-07
3403 Recent loss of the Dim2 DNA methyltransferase decreases mutation rate in repeats and changes evolutionary trajectory in a fungal pathogen
Moeller, M.; Habig, M.; Lorrain, C.; Feurtey, A.; Haueisen, J.; Fagundes, W. C.; Alizadeh, A.; Freitag, M.; Stukenbrock, E. H.
10.1101/2020.03.27.012203 — genetics — Posted on 2020-09-07
3404 Domestication of the emblematic white cheese-making fungus Penicillium camemberti and its diversification into two varieties
Ropars, J.; Didiot, E.; Rodriguez de la Vega, R. C.; Bennetot, B.; Coton, M.; Poirier, E.; Coton, E.; Snirc, A.; Le Prieur, S.; Giraud, T.
10.1101/2020.02.12.945238 — evolutionary biology — Posted on 2020-09-07
3408 Lateral Hypothalamic GABAergic neurons encode and potentiate sucrose palatability
Garcia, A.; Coss, A.; Luis-Islas, J.; Puron-Sierra, L.; Luna, M.; Villavicencio, M.; Gutierrez, R.
10.1101/2020.06.30.180646 — neuroscience — Posted on 2020-09-07
3410 A combined pipeline for quantitative analysis of human brain cytoarchitecture
Costantini, I.; Mazzamuto, G.; Roffilli, M.; Laurino, A.; Castelli, F. M.; Neri, M.; Lughi, G.; Simonetto, A.; Lazzeri, E.; Pesce, L.; Destrieux, C.; Silvestri, L.; Conti, V.; Guerrini, R.; Pavone, F. S.
10.1101/2020.08.06.219444 — neuroscience — Posted on 2020-09-07
3412 Role of channels in the oxygen permeability of red blood cells
Zhao, P.; Geyer, R. R.; Salameh, A. I.; Wass, A. B.; Taki, S.; Huffmann, D. E.; Meyerson, H. J.; Gros, G.; Occhipinti, R.; Moss, F. J.; Boron, W. F.
10.1101/2020.08.28.265066 — physiology — Posted on 2020-09-07
3413 In silico Characterization of Class II Plant Defensins from Arabidopsis thaliana
Costa, L. M.; Pires, A. S.; Damaceno, N. B.; Rigueiras, P. O.; Maximiano, M. R.; Franco, O. L.; Porto, W. F.
10.1101/2020.04.27.065185 — bioinformatics — Posted on 2020-09-07
3415 Diet induces parallel changes to host gut microbiota and problem solving performance in a wild bird.
Davidson, G.; Wiley, N.; Cooke, A. C.; Johnson, C. N.; Fouhy, F.; Reichert, M. S.; de la Hera, I.; Crane, J. M. S.; Kulahci, I. G.; Ross, R. P.; Stanton, C.; Quinn, J. L.
10.1101/827741 — ecology — Posted on 2020-09-07
3418 Evolutionary stasis of the pseudoautosomal boundary in strepsirrhine primates
Shearn, R.; Wright, A.; Mousset, S.; Regis, C.; Penel, S.; Lemaitre, J. F.; Douay, G.; Crouau-Roy, B.; Lecompte, E.; Marais, G.
10.1101/445072 — evolutionary biology — Posted on 2020-09-07
3419 NLRC5 regulates expression of MHC-I and provides a target for anti-tumor immunity in transmissible cancers
Ong, C. E. B.; Patchett, A. L.; Darby, J. M.; Chen, J.; Liu, G.-S.; Lyons, A. B.; Woods, G. M.; Flies, A. S.
10.1101/2020.09.06.274720 — immunology — Posted on 2020-09-07
3420 Visual speech differentially modulates beta, theta, and high gamma bands in auditory cortex
Ganesan, K.; Plass, J.; Beltz, A. M.; Liu, Z.; Grabowecky, M.; Suzuki, S.; Stacey, W. C.; Wasade, V. S.; Towle, V. L.; Tao, J. X.; Wu, S.; Issa, N. P.; Brang, D.
10.1101/2020.09.07.284455 — neuroscience — Posted on 2020-09-07
3421 Chronic Pain Patients Exhibit Individually Unique Cortical Signatures of Pain
Mayr, A.; Jahn, P.; Stankewitz, A.; Deak, B.; Winkler, A.; Witkovsky, V.; Eren, O.; Straube, A.; Schulz, E.
10.1101/2020.09.05.284117 — neuroscience — Posted on 2020-09-07
3427 Hmx gene conservation identifies the evolutionary origin of vertebrate cranial ganglia
Papadogiannis, V.; Parker, H. J.; Pennati, A.; Patthey, C.; Bronner, M. E.; Shimeld, S. M.
10.1101/2020.09.07.281501 — evolutionary biology — Posted on 2020-09-07
3430 Dopamine D2 receptors modulate the cholinergic pause and inhibitory learning
Gallo, E. F.; Greenwald, J.; Teboul, E.; Martyniuk, K. M.; Li, Y.; Javitch, J. A.; Balsam, P. D.; Kellendonk, C.
10.1101/2020.09.07.284612 — neuroscience — Posted on 2020-09-07
3432 TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation
Fan, X.; Masamsetti, V. P.; Sun, J. Q. J.; Engholm-Keller, K.; Osteil, P.; Studdert, J.; Graham, M. E.; Fossat, N.; Tam, P. P. L.
10.1101/2020.09.06.285387 — developmental biology — Posted on 2020-09-07
3435 Combination of photoactivation with lattice light-sheet imaging reveals untemplated, lamellar ruffle generation by PA-Rac1
Leyden, F.; Uthishtran, S.; Moorthi, U. K.; York, H. M.; Patil, A.; Gandhi, H.; Petrov, E. P.; Arumugam, S.
10.1101/2020.09.01.276824 — biophysics — Posted on 2020-09-06
3439 MiREDiBase: a manually curated database of editing events in microRNAs
Marceca, G. P.; Distefano, R.; Tomasello, L.; Lagana, A.; Russo, F.; Calore, F.; Romano, G.; Bagnoli, M.; Gasparini, P.; Ferro, A.; Acunzo, M.; Ma, Q.; Croce, C. M.; Nigita, G.
10.1101/2020.09.04.283689 — bioinformatics — Posted on 2020-09-06
3440 Sea-crossing along migratory flyways is limited more strongly by wind than by lack of uplift
Nourani, E.; Becciu, P.; Bierregaard, R. O.; Duriez, O.; Giokas, S.; Higuchi, H.; Kassara, C.; Kulikova, O.; Lecomte, N.; Monti, F.; Pokrovsky, I.; Sforzi, A.; Therrien, J.-F.; Tsiopelas, N.; Yamaguchi, N. M.; Wikelski, M.; Safi, K.
10.1101/2020.09.04.282939 — animal behavior and cognition — Posted on 2020-09-06
3447 Myosin 7b is a regulatory long noncoding RNA (lncMYH7b) in the human heart
Broadwell, L. J.; Smallegan, M. J.; Rigby, K. M.; Navarro-Arriola, J. S.; Montgomery, R. L.; Rinn, J. L.; Leinwand, L. A.
10.1101/2020.09.06.285189 — molecular biology — Posted on 2020-09-06
3448 NF-κB modifies the mammalian circadian clock through interaction with the core clock protein BMAL1
Liu, A. C.; Shen, Y.; Wang, W.; Endale, M.; Francey, L. J.; Harold, R. L.; Hammers, D. W.; Huo, Z.; Partch, C. L.; Hogenesch, J.; Wu, Z.-H.
10.1101/2020.09.06.285254 — molecular biology — Posted on 2020-09-06
3449 Transgenic pyrimethamine-resistant P. falciparum reveals transmission blocking potency of P218, a novel antifolate
Posayapisit, N.; Pengon, J.; Prommana, P.; Shoram, M.; Yuthavong, Y.; Uthaipibull, C.; Kamchonwongpaisan, S.; Jupatanakul, N.
10.1101/2020.09.06.284786 — microbiology — Posted on 2020-09-06
3451 Novel Three-Dimensional Organoid Sarcoidosis Granuloma Model
Calcagno, T. M.; Zhang, C.; Tian, R.; Ebrahimi, B.; Mirsaeidi, M.
10.1101/2020.09.05.284398 — immunology — Posted on 2020-09-06
3452 Relationship between Regional White Matter Hyperintensities and Alpha Oscillations in Older Adults
Kumral, D.; Cesnaite, E.; Beyer, F.; Hofmann, S. M.; Hensch, T.; Sander, C.; Hegerl, U.; Haufe, S.; Villringer, A.; Witte, V.; Nikulin, V.
10.1101/2020.09.04.283200 — neuroscience — Posted on 2020-09-06
3454 Conserved cysteines in titin sustain the mechanical function of cardiomyocytes
Herrero-Galan, E.; Dominguez, F.; Martinez-Martin, I.; Sanchez-Gonzalez, C.; Vicente, N.; Lalaguna, L.; Bonzon-Kulichenko, E.; Calvo, E.; Gonzalez-Lopez, E.; Cobo-Marcos, M.; Bornstein, B.; Briceno, A.; Ochoa, J. P.; Garcia-Aznar, J. M.; Suay-Corredera, C.; Pricolo, M. R.; Fernandez-Trasancos, A.; Velazquez-Carreras, D.; Badia Careaga, C.; Prados, B.; Gutierrez-Aguera, F.; Abdellatif, M.; Sedej, S.; Rainer, P. P.; Giganti, D.; Giovinazzo, G.; Bernal, J. A.; Perez-Jimenez, R.; Rasmussen, T. B.; Hey, T. M.; Vivo-Ortega, I.; Piqueras-Flores, J.; Lara-Pezzi, E.; Vazquez, J.; Garcia-Pavia, P.; Aleg
10.1101/2020.09.05.282913 — physiology — Posted on 2020-09-06
3455 CASCADES, a novel SOX2 super-enhancer associated long noncoding RNA, regulates cancer stem cell specification and differentiation in glioblastoma multiforme
Shahzad, U.; Li, C.; Johnston, M.; Wang, J. J.; Sabha, N.; Varn, F. S.; Riemenschneider, A.; Krumholtz, S.; Meda, P.; Smith, C.; Karamchandani, J.; Watts, J. K.; Verhaak, R. G. W.; Gallo, M.; Rutka, J. T.; Das, S.
10.1101/2020.09.05.284349 — cancer biology — Posted on 2020-09-06
3456 Combination of photoactivation with lattice light-sheet imaging reveals PA-Rac1 generates untemplated, lamellar ruffles
Leyden, F.; Uthishtran, S.; Moorthi, U. K.; York, H. M.; Patil, A.; Gandhi, H.; Petrov, E. P.; Arumugam, S.
10.1101/2020.09.01.276824 — biophysics — Posted on 2020-09-06
3457 Notable sequence homology of the ORF10 protein introspects the architecture of SARS-COV-2
Hassan, S. S.; Attrish, D.; Ghosh, S.; Pal Choudhury, P.; Uversky, V. N.; Uhal, B.; Lundstrom, K.; Rezaei, N.; Aljabali, A. A. A.; Seyran, M.; Pizzol, D.; Adadi, P.; Abd El-Aziz, T. M.; Soares, A.; Kandimalla, R.; Tambuwala, M.; Lal, A.; Azad, G. K.; P. Sherchan, S.; Baetas-da-Cruz, W.; Palu, G.; Brufsky, A.
10.1101/2020.09.06.284976 — bioinformatics — Posted on 2020-09-06
3464 How moral values influence conservation: a framework to capture different management perspectives
Latombe, G.; Lenzner, B.; Schertler, A.; Dullinger, S.; Jaric, I.; Pauchard, A.; Wilson, J. R. U.; Essl, F.
10.1101/2020.09.04.282947 — ecology — Posted on 2020-09-06
3465 Effects of phylogeny on coexistence in model communities
Servan, C. A.; Capitan, J. A.; Miller, Z. R.; Allesina, S.
10.1101/2020.09.04.283507 — ecology — Posted on 2020-09-06
3466 Detection of Plasmodium vivax in a liver sample of a howler-monkey: one evidence more in favour of the identity between Plasmodium simium and P. vivax
Buery, J. C.; Duarte, A. M. R. d. C.; Alencar, F. E. C.; Furieri, C.; Mendes, S. L.; Loss, A. C.; Vicente, C. R.; Fux, B.; Rezende, H. R.; Cravo, P. V.; Medeiros, M. M.; Arez, A. P.; Cerutti, C.
10.1101/2020.09.06.279869 — molecular biology — Posted on 2020-09-06
3470 Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation and survival
Baker, N.; Catta-Preta, C. M. C.; Neish, R.; Sadlova, J.; Powell, B.; Alves-Ferreira, E. V. C.; Geohegan, V.; Carnielli, J. B. T.; Newling, K.; Hughes, C.; Vojtkova, B.; Anand, J.; Mihut, A.; Walrad, P.; Wilson, L. G.; Pitchford, J. W.; Volf, P.; Mottram, J. C.
10.1101/2020.09.06.279091 — microbiology — Posted on 2020-09-06
3472 Computationally validated SARS-CoV-2 CTL and HTL Multi-Patch Vaccines designed by reverse epitomics approach, shows potential to cover large ethnically distributed human population worldwide
Srivastava, S.; Verma, S.; Kamthania, M.; Agarwal, D.; Saxena, A. K.; Kolbe, M.; Singh, S.; Kotnis, A.; Rathi, B.; Nayar, S. A.; Shin, H.-J.; Vashisht, K.; Pandey, K. C.
10.1101/2020.09.06.284992 — immunology — Posted on 2020-09-06
3477 Pre-clinical studies of a recombinant adenoviral mucosal vaccine to prevent SARS-CoV-2 infection
Moore, A. C.; Dora, E. G.; Peinovich, N.; Tucker, K. P.; Lin, K.; Cortese, M.; Tucker, S.
10.1101/2020.09.04.283853 — immunology — Posted on 2020-09-06
3478 Genomic analysis reveals local transmission of SARS-CoV-2 in early pandemic phase in Peru
Padilla Rojas, C.; Vega Chozo, K.; Galarza Perez, M.; Bailon Calderon, H.; Lope Pari, P.; Balbuena Torres, J.; Garcia Neyra, D.; Huaringa Nunez, M.; Rojas Serrano, N.; Caceres Rey, O.
10.1101/2020.09.05.284604 — genomics — Posted on 2020-09-06
3480 DNA barcoding analysis of more than 1000 marine yeast isolates reveals previously unrecorded species
PrasannaKumar, C.; Velmurugan, S.; Subramanian, K.; Pugazhvendan, S. R.; Senthil Nagaraj, D.; Feroz Khan, K.; Sadiappan, B.; Manokaran, S.; Hemalatha, K. R.; Sivamaruthi, B. S.; Chaiyasut, C.
10.1101/2020.08.29.273490 — microbiology — Posted on 2020-09-06
3481 A neural circuit for flexible control of persistent behavioral states
Ji, N.; Madan, G. K.; Fabre, G. I.; Dayan, A.; Baker, C. M.; Nwabudike, I.; Flavell, S. W.
10.1101/2020.02.04.934547 — neuroscience — Posted on 2020-09-06
3482 Structural basis of client specificity in mitochondrial membrane-protein chaperones
Sucec, I.; Wang, Y.; Dakhlaoui, O.; Weinhäupl, K.; Jores, T.; Costa, D.; Hessel, A.; Brennich, M.; Rapaport, D.; Lindorff-Larsen, K.; Bersch, B.; Schanda, P.
10.1101/2020.06.08.140772 — biophysics — Posted on 2020-09-06
3483 Genome assembly and transcriptome analysis provide insights into the anti-schistosome mechanism of Microtus fortis
Li, H.; Wang, Z.; Chai, S.; Bai, X.; Ding, G.; Li, J.; Xiao, Q.; Miao, B.; Lin, W.; Feng, J.; Gao, C.; Li, Y.; Li, B.; Hu, W.; Lin, J.; Fu, Z.; Xie, J.; Li, Y.
10.1101/2020.09.03.282319 — bioinformatics — Posted on 2020-09-06
3486 Single Cell Transcriptomics of Human Native Kidney and Kidney Allografts and New Insights into the Mechanism of Fibrosis
Suryawanshi, H.; Yang, H.; Lubetzky, M.; Morozov, P.; Lagman, M.; Alonso, A.; Li, C.; Snopkowski, C.; Mueller, F.; Lee, J.; Dadhania, D.; Salvatore, S.; Seshan, S.; Sharma, V.; Suthanthiran, M.; Tuschl, T.; Muthukumar, T.
10.1101/2020.09.03.281733 — molecular biology — Posted on 2020-09-06
3489 Cell-to-cell spread inhibiting antibodies constitute a correlate of protection against Herpes Simplex Virus Type 1 reactivations
Wolf, S.; Mira, A.; Dittrich, R.; Dirks, M.; Schipper, L.; Aufderhorst, U. W.; Rainer, K.; Dittmer, U.; Witzke, O.; Giebel, B.; Trilling, M.; Heilingloh, C. S.; Lotfi, R.; Roggendorf, M.; Krawczyk, A.
10.1101/2020.09.03.282483 — immunology — Posted on 2020-09-06
3491 Pharmacological and genetic manipulations of Ca2+ signaling have contrasting effects on auxin-regulated trafficking
Vanneste, S.; Wang, R.; Himschoot, E.; Grenzi, M.; Chen, J.; Krebs, M.; Schumacher, K.; Nowack, M. K.; Van Damme, D.; De Smet, I.; Beeckman, T.; Costa, A.; Friml, J.
10.1101/2020.09.04.283101 — cell biology — Posted on 2020-09-06
3492 Melanopsin retinal ganglion cell-driven contribution to visual and cognitive brain responses in LHON
Evangelisti, S.; La Morgia, C.; Testa, C.; Manners, D. N.; Brizi, L.; Bianchini, C.; Carbonelli, M.; Barboni, P.; Sadun, A. A.; Tonon, C.; Carelli, V.; Vandewalle, G.; Lodi, R.
10.1101/2020.09.04.282830 — neuroscience — Posted on 2020-09-06
3505 Laser nanobubbles induce immunogenic cell death in breast cancer
Nguyen, H. T. M.; Katta, N.; Widman, J. A.; Takematsu, E.; Feng, X.; Torres, S. H.; Betancourt, T.; Baker, A.; Suggs, L. J.; Milner, T. E.; Tunnell, J. W.
10.1101/2020.09.04.283846 — bioengineering — Posted on 2020-09-05
3511 Integrated omics networks reveal the temporal signaling events of brassinosteroid response in Arabidopsis
Clark, N. M.; Nolan, T. M.; Wang, P.; Song, G.; Montes, C.; Guo, H.; Sozzani, R.; Yin, Y.; Walley, J. W.
10.1101/2020.09.04.283788 — plant biology — Posted on 2020-09-05
3514 Determination of the molecular reach of the protein tyrosine phosphatase SHP-1
Clemens, L.; Kutuzov, M.; Bayer, K. V.; Goyette, J.; Allard, J.; Dushek, O.
10.1101/2020.09.04.283341 — biophysics — Posted on 2020-09-05
3517 Saccharomyces cerevisiae Ecm2 Modulates the Catalytic Steps of pre-mRNA Splicing
van der Feltz, C.; Nikolai, B.; Schneider, C.; Paulson, J. C.; Fu, X.; Hoskins, A. A.
10.1101/2020.09.05.284281 — biochemistry — Posted on 2020-09-05
3518 Impact of low-frequency coding variants on human facial shape
Liu, D.; Alhazmi, N.; Matthews, H.; Lee, M. K.; Li, J.; Hecht, J. T.; Wehby, G. L.; Moreno, L. M.; Heike, C. L.; Roosenboom, J.; Feingold, E.; Marazita, M. L.; Claes, P.; Liao, E. C.; Weinberg, S. M.; Shaffer, J. R.
10.1101/2020.07.30.227769 — genetics — Posted on 2020-09-05
3519 Cryptic diversity masks ecologically distinct coral species on tropical reefs
Bongaerts, P.; Cooke, I. R.; Ying, H.; Wels, D.; den Haan, S.; Hernandez-Agreda, A.; Brunner, C. A.; Dove, S.; Englebert, N.; Eyal, G.; Foret, S.; Grinblat, M.; Hay, K. B.; Harii, S.; Hayward, D. C.; Lin, Y.; Mihaljevic, M.; Moya, A.; Muir, P.; Sinniger, F.; Smallhorn-West, P.; Torda, G.; Ragan, M. A.; van Oppen, M. J.; Hoegh-Guldberg, O.
10.1101/2020.09.04.260208 — evolutionary biology — Posted on 2020-09-05
3520 RNA LEVER Mediates Long-Range Regulation of ε-globin by Keeping PRC2 in Check
Teo, W. W.; Cao, X.; Wu, C.-S.; Tan, H. K.; Zhou, Q.; Yang, H.; Chai, L.; Tenen, D. G.
10.1101/2020.09.05.282624 — molecular biology — Posted on 2020-09-05
3522 Visualizing Borrelia burgdorferi infection using a small molecule imaging probe.
Sell, M. G.; Alcorta, D. A.; Padilla, A. E.; Nollner, D. W.; Hasenkampf, N. R.; Lambert, H. S.; Embers, M. E.; Spector, N. L.
10.1101/2020.09.04.284067 — microbiology — Posted on 2020-09-05
3524 Leaky severe combined immunodeficiency in mice lacking non-homologous end joining factors XLF and MRI
Castaneda-Zegarra, S.; Zhang, Q.; Alirezaylavasani, A.; Fernandez-Berrocal, M.; Yao, R.; Oksenych, V.
10.1101/2020.03.04.976829 — immunology — Posted on 2020-09-05
3525 TRPV1 feed-forward sensitisation depends on COX2 upregulation in primary sensory neurons
Li, T.; Wang, G.; Hui, V. C. C.; Saad, D.; de Sousa Valente, J.; La Montanara, P.; Nagy, I.
10.1101/2020.09.05.267708 — neuroscience — Posted on 2020-09-05
3526 HIV antiretrovirals have differential effects on viability and function in human iPSC-derived neurons and neural precursor cells
Smith, A. S.; Ankam, S.; Basa, R. C. B.; Gordon, K. L.; Terskikh, A. V.; Jordan-Sciutto, K. L.; Price, J.; McDonough, P. M.
10.1101/2020.09.05.284422 — neuroscience — Posted on 2020-09-05
3528 High throughput instrument to screen fluorescent proteins under two-photon excitation
Molina, R. S.; King, J.; Franklin, J.; Clack, N.; McRaven, C.; Goncharov, V.; Flickinger, D.; Svoboda, K.; Drobizhev, M.; Hughes, T. E.
10.1101/2020.09.04.283572 — neuroscience — Posted on 2020-09-05
3530 Impact of chronic transcranial Random-Noise Stimulation (tRNS) on prefrontal cortex excitation-inhibition balance in juvenile mice.
Sanchez-Leon, C. A.; Sanchez-Lopez, A.; Gomez-Climent, M. A.; Cordones, I.; Cohen Kadosh, R.; Marquez-Ruiz, J.
10.1101/2020.09.04.282889 — neuroscience — Posted on 2020-09-05
3531 Microscale physiological events on the human cortical surface
Paulk, A. C.; Yang, J. C.; Cleary, D. R.; Soper, D. J.; Halgren, M.; O'Donnell, A. R.; Lee, S. H.; Ganji, M.; Ro, Y. G.; Oh, H.; Hossain, L.; Lee, J.; Tchoe, Y.; Rogers, N.; Kilic, K.; Ryu, S. B.; Lee, S. W.; Hermiz, J.; Gilja, V.; Ulbert, I.; Fabo, D.; Devinsky, O.; Madsen, J. R.; Schomer, D.; Eskandar, E. N.; Lee, J. W.; Maus, D.; Devor, A.; Fried, S. I.; Jones, P. S.; Nahed, B. V.; Ben-Haim, S.; Bick, S. K.; Raslan, A. M. T.; Richardson, R. M.; Siler, D. A.; Cahill, D. P.; Williams, Z. M.; Cosgrove, G. R.; Dayeh, S. A.; Cash, S. S.
10.1101/770743 — neuroscience — Posted on 2020-09-05
3532 Strengthening of marine amphipod DNA barcode libraries for environmental monitoring
PrasannaKumar, C.; Manikantan, G.; Vijaylaxmi, J.; Gunalan, B.; Manokaran, S.; Pugazhvendan, S. R.
10.1101/2020.08.26.268896 — zoology — Posted on 2020-09-05
3536 ACDC: Automated Cell Detection and Counting for Time-lapse Fluorescence Microscopy
Rundo, L.; Tangherloni, A.; Tyson, D. R.; Betta, R.; Militello, C.; Spolaor, S.; Nobile, M. S.; Besozzi, D.; Lubbock, A. L. R.; Quaranta, V.; Mauri, G.; Lopez, C. F.; Cazzaniga, P.
10.1101/2020.07.14.202804 — bioinformatics — Posted on 2020-09-05
3538 Quantitative occupancy of myriad transcription factors from one DNase experiment enables efficient comparisons across conditions
Luo, K.; Zhong, J.; Safi, A.; Hong, L. K.; Tewari, A. K.; Song, L.; Reddy, T. E.; Ma, L.; Crawford, G. E.; Hartemink, A. J.
10.1101/2020.06.28.171587 — bioinformatics — Posted on 2020-09-05
3540 Chromatin regulatory dynamics of early human small intestinal development using a directed differentiation model
Hung, Y.-H.; Huang, S.; Dame, M. K.; Yu, Q.; Yu, Q. C.; Zeng, Y. A.; Camp, J. G.; Spence, J. R.; Sethupathy, P.
10.1101/2019.12.18.881219 — genomics — Posted on 2020-09-05
3541 MyoD is a structure organizer of 3D genome architecture in muscle cells
Chen, Q.; Chen, F.; Wang, R.; Shi, M.; Chen, A. K.; Ma, Z.; Li, G.; Wang, M.; Li, H.; Zhang, X.; Ma, J.; Zhong, J.; Chen, M.; Zhang, M. Q.; Zhang, Y.; Chen, Y.; Zhu, D.
10.1101/2020.08.29.273375 — genomics — Posted on 2020-09-05
3542 Population structure of eulachon Thaleichthys pacificus from Northern California to Alaska using single nucleotide polymorphisms from direct amplicon sequencing
Sutherland, B. J. G.; Candy, J.; Mohns, K.; Cornies, O.; Jonsen, K.; Le, K.; Gustafson, R. G.; Nichols, K. M.; Beacham, T. D.
10.1101/2020.05.31.126268 — genetics — Posted on 2020-09-05
3543 Mutational landscapes of normal breast during age and pregnancy determine cancer risk
Cereser, B.; Tabassum, N.; Del Bel Belluz, L.; Yiu, A.; Zagorac, S.; Miere, C.; Werner, B.; Moderau, N.; Jeffries-Jones, A. R.; Stebbing, J.
10.1101/2020.09.04.277715 — genetics — Posted on 2020-09-05
3544 Sex, males, and hermaphrodites in the scale insect Icerya purchasi
Mongue, A. J.; Michaelides, S.; Coombe, O.; Tena, A.; Kim, D.-S.; Normark, B. B.; Gardener, A.; Hoddle, M. S.; Ross, L.
10.1101/2020.09.04.281618 — evolutionary biology — Posted on 2020-09-05
3545 Mosaic evolution of molecular pathways for sex pheromone communication in a butterfly
Nieberding, C. M.; Beldade, P.; Baumle, V.; San Martin, G.; Arun, A.; Lognay, G.; Montagne, N.; Bastin-Heline, L.; Jacquin-Joly, E.; Noirot, C.; Klopp, C.; Visser, B.
10.1101/2020.09.04.279224 — evolutionary biology — Posted on 2020-09-05
3548 Polygenic adaptation of rosette growth variation in Arabidopsis thaliana populations
Wieters, B.; Steige, K.; He, F.; Koch, E.; Ramos-Onsins, S.; Gu, H. Y.; Guo, Y.; Sunyaev, S.; de Meaux, J.
10.1101/2020.03.31.018341 — evolutionary biology — Posted on 2020-09-05
3549 The Pleistocene species pump past its prime: evidence from European butterfly sister species
Ebdon, S.; Laetsch, D. R.; Dapporto, L.; Hayward, A.; Ritchie, M. G.; Dinca, V.; Vila, R.; Lohse, K.
10.1101/2020.09.04.282962 — evolutionary biology — Posted on 2020-09-05
3550 RecA levels modulate biofilm development in Acinetobacter baumannii
Ching, C.; Muller, P.; Brychcy, M.; Reverdy, A.; Nguyen, B.; Downs, M.; Regan, S.; Isley, B.; Fowle, W.; Chai, Y.; Godoy, V. G.
10.1101/809392 — microbiology — Posted on 2020-09-05
3554 Deletion of Mcpip1 in Mcpip1AlbKO mice recapitulates the phenotype of human primary biliary cholangitis
Kotlinowski, J.; Hutsch, T.; Czyzynska-Cichon, I.; Wadowska, M.; Pydyn, N.; Jasztal, A.; Kij, A.; Dobosz, E.; Lech, M.; Miekus, K.; Pospiech, E.; Fu, M.; Jura, J.; Koziel, J.; Chlopicki, S.
10.1101/2020.09.05.250522 — pathology — Posted on 2020-09-05
3556 Aging selectively dampens oscillation of lipid abundance in white and brown adipose tissue
Held, N. M.; Buijink, R.; Elfrink, H. L.; Kooijman, S.; Janssens, G. E.; Vaz, F. M.; Michel, S.; Houtkooper, R. H.; Weeghel van, M.
10.1101/2020.09.04.283226 — biochemistry — Posted on 2020-09-05
3561 Maternal cortisol is associated with neonatal amygdala microstructure and connectivity in a sexually dimorphic manner
Stoye, D. Q.; Blesa, M.; Sullivan, G.; Galdi, P.; Lamb, G. J.; Black, G. S.; Quigley, A. J.; Thrippleton, M. J.; Bastin, M. E.; Reynolds, R. M.; Boardman, J. P.
10.1101/2020.06.16.154922 — neuroscience — Posted on 2020-09-05
3564 Integrated single cell analysis of chromatin accessibility and cell surface markers
Swanson, E.; Lord, C.; Reading, J.; Heubeck, A. T.; Savage, A. K.; Green, R.; Torgerson, T. R.; Bumol, T. F.; Graybuck, L. T.; Skene, P. J.
10.1101/2020.09.04.283887 — immunology — Posted on 2020-09-04
3565 Transposon mutagenesis identifies cooperating genetic drivers during keratinocyte transformation and cutaneous squamous cell carcinoma progression
Aiderus, A.; Newberg, J. Y.; Guzman-Rojas, L.; Contreras-Sandoval, A. M.; Meshey, A. L.; Jones, D. J.; Amaya-Manzanares, F.; Rangel, R.; Ward, J. M.; Lee, S. C.; Ban, K. H.-K.; Rogers, K.; Rogers, S. M.; Selvanesan, L.; McNoe, L. A.; Copeland, N. G.; Jenkins, N. A.; Tsai, K. Y.; Black, M. A.; Mann, K. M.; Mann, M. B.
10.1101/2019.12.24.887968 — cancer biology — Posted on 2020-09-04
3566 Hydrogen-deuterium exchange reveals a dynamic DNA binding map of Replication Protein A
Ahmed, F.; Patterson, A.; Devershetty, J.; Mattice, J.; Pokhrel, N.; Bothner, B.; Antony, E.
10.1101/2020.09.04.283879 — biochemistry — Posted on 2020-09-04
3567 A telomere to telomere assembly of Oscheius tipulae and the evolution of rhabditid nematode chromosomes
Gonzalez de la Rosa, P. M.; Thomson, M.; Trivedi, U.; Tracey, A.; Tandonnet, S.; Blaxter, M.
10.1101/2020.09.04.283127 — genomics — Posted on 2020-09-04
3569 Population-specific causal disease effect sizes in functionally important regions impacted by selection
Shi, H.; Gazal, S.; Kanai, M.; Koch, E. M.; Schoech, A. P.; Siewert, K. M.; Kim, S. S.; Luo, Y.; Amariuta, T.; Huang, H.; Okada, Y.; Raychaudhuri, S.; Sunyaev, S. R.; Price, A. L.
10.1101/803452 — genetics — Posted on 2020-09-04
3571 Capture of mouse and human stem cells with features of formative pluripotency
Kinoshita, M.; Barber, M.; Mansfield, W.; Cui, Y.; Spindlow, D.; Stirparo, G. G.; Dietmann, S.; Nichols, J.; Smith, A.
10.1101/2020.09.04.283218 — developmental biology — Posted on 2020-09-04
3573 Method comparison studies of telomere length measurement using qPCR approaches: a critical appraisal of the literature
Lindrose, A. R.; McLester-Davis, L. W. Y.; Tristano, R. I.; Kataria, L.; Gadalla, S. M.; Eisenberg, D. T. A.; Verhulst, S.; Drury, S.
10.1101/2020.09.04.282632 — molecular biology — Posted on 2020-09-04
3574 Mutagenic mechanisms of cancer-associated DNA polymerase ε alleles
Herzog, M.; Alonso-Perez, E.; Salguero, I.; Warringer, J.; Adams, D. J.; Jackson, S.; Puddu, F.
10.1101/2020.09.04.270124 — molecular biology — Posted on 2020-09-04
3575 Seroprevalence of SARS-CoV-2 specific IgG antibodies in District Srinagar, northern India - a cross-sectional study
Khan, S. M. S.; Qurieshi, M. A.; Haq, I.; Majid, S.; Bhat, A. A.; Nabi, S.; Ganai, N. A.; Zahoor, N.; Nisar, A.; Chowdri, I. N.; Qazi, T. B.; Kousar, R.; Lone, A. A.; Sabah, I.; Nabi, S.; Sumji, I. A.; Kawoosa, M. F.; Ayoub, S.
10.1101/2020.09.04.282640 — immunology — Posted on 2020-09-04
3576 Pancreatic cancer cells assemble a CXCL12-keratin 19 coating to resist immunotherapy
Wang, Z.; Yan, R.; Li, J.; Gao, Y.; Moresco, P.; Yao, M.; Hechtman, J. F.; Weiss, M. J.; Janowitz, T.; Fearon, D. T.
10.1101/776419 — immunology — Posted on 2020-09-04
3577 CyDAP-A fluorescent probe for cytosolic dopamine detection
Jeng, J.-Y.; Sun, L.; Wang, J.-C.; Lin, C.-Y.; Hung, C.-P.; Chu, L.-A.; Chang, H.-Y.; Chiang, A.-S.; Sang, T.-K.
10.1101/2020.09.04.283911 — neuroscience — Posted on 2020-09-04
3579 Asymmetric Functional Gradients in the Human Subcortex
Guell, X.; Schmahmann, J. D.; Gabrieli, J. D.; Ghosh, S. S.; Geddes, M. R.
10.1101/2020.09.04.283820 — neuroscience — Posted on 2020-09-04
3580 Chromatin State Dynamics Confers Specific Therapeutic Strategies in Enhancer Subtypes of Colorectal Cancer
Orouji, E.; Raman, A. T.; Singh, A. K.; Sorokin, A.; Arslan, E.; Ghosh, A. K.; Schulz, J.; Terranova, C. J.; Tang, M.; Maitituoheti, M.; Callahan, S. C.; Tomczak, K. J.; Jiang, Z.; Davis, J. S.; Ghosh, S.; Lee, H. M.; Reyes-Uribe, L.; Chang, K.; Liu, Y.; Chen, H.; Azhdarnia, A.; Morris, J. S.; Vilar, E.; Carmon, K. S.; Kopetz, S.; Rai, K.
10.1101/2020.09.04.283838 — cancer biology — Posted on 2020-09-04
3581 CRISPR/Cas9 technology abolishes the BCR/ABL1 oncogene effect in chronic myeloid leukemia and restores normal hematopoiesis
Vuelta, E.; Ordonez, J. L.; Alonso-Perez, V.; Mendez, L.; Hernandez-Carabias, P.; Saldana, R.; Sevilla, J.; Sebastian, E.; Muntion, S.; Sanchez-Guijo, F.; Hernandez-Rivas, J. M.; Garcia-Tunon, I.; Sanchez-Martin, M. A.
10.1101/2020.08.05.237610 — cancer biology — Posted on 2020-09-04
3582 In Situ Unzipping of Long, High Molecular Weight DNA in Solid State Nanopores
Losakul, R.; Tobar, D. E.; Pfeffer, A. M.; Gutierrez, A.; Schipper, R.; Jehle, W. A.; Postma, H. W. C.
10.1101/2020.07.21.214445 — biophysics — Posted on 2020-09-04
3586 Chemical validation of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase using fragment linking and CRISPR interference
El Bakali, J.; Blaszczyk, M.; Evans, J. C.; Boland, J. A.; McCarthy, W. J.; Dias, M. V. B.; Coyne, A. G.; Mizrahi, V.; Blundell, T. L.; Abell, C.; Spry, C.
10.1101/2020.09.04.280388 — biochemistry — Posted on 2020-09-04
3587 Plasmids shape the diverse accessory resistomes of Escherichia coli ST131
Decano, A. G.; Tran, N.; Al-Foori, H.; Al-Awadi, B.; Leigh Campbell, L.; Ellison, K.; Mirabueno, L. P.; Nelson, M.; Power, S.; Smith, G.; Smyth, C.; Vance, Z.; Rahm, A.; Downing, T.
10.1101/2020.05.07.081380 — genomics — Posted on 2020-09-04
3589 The essential role of Dnmt1 in gametogenesis in the large milkweed bug Oncopeltus fasciatus
Washington, J. T.; Cavender, K. R.; Amukamara, A. U.; McKinney, E. C.; Schmitz, R. J.; Moore, P. J.
10.1101/2020.07.23.218180 — evolutionary biology — Posted on 2020-09-04
3592 Genomic diversity of Escherichia coli isolates from healthy children in rural Gambia
Foster-Nyarko, E.; Alikhan, N.-F.; Ikumapayi, U. N.; Golam, S.; Hossain, M. J.; Okoi, C.; Tientcheu, P.-E.; Defernez, M.; OGrady, J.; Antonio, M.; Pallen, M. J.
10.1101/2020.08.28.271627 — ecology — Posted on 2020-09-04
3593 Clumpy coexistence in phytoplankton: The role of functional similarity in community assembly
Graco-Roza, C.; Segura, A. M.; Kruk, C.; Domingos, P.; Soininen, J.; Marinho, M. M.
10.1101/869966 — ecology — Posted on 2020-09-04
3595 Airway Basal Cells show a dedifferentiated KRT17high Phenotype and promote Fibrosis in Idiopathic Pulmonary Fibrosis
Jaeger, B.; Schupp, J. C.; Plappert, L.; Terwolbeck, O.; Kayser, G.; Engelhard, P.; Adams, T. S.; Zweigerdt, R.; Kempf, H.; Lienenklaus, S.; Garrels, W.; Nazarenko, I.; Jonigk, D.; Wygrecka, M.; Klatt, D.; Schambach, A.; Kaminski, N.; Prasse, A.
10.1101/2020.09.04.283408 — cell biology — Posted on 2020-09-04
3596 Nanoscopy on the Chea(i)p
Diederich, B.; Helle, O. I.; Then, P.; Carravilla, P.; Schink, K. O.; Hornung, F.; Deinhardt-Emmer, S.; Eggeling, C.; Ahluwalia, B. S.; Heintzmann, R.
10.1101/2020.09.04.283085 — microbiology — Posted on 2020-09-04
3597 Systematic comparison of high-throughput single-cell RNA-seq methods for immune cell profiling
Yamawaki, T. M.; Lu, D. R.; Ellwanger, D. C.; Bhatt, D.; Manzanillo, P.; Zhou, H.; Yoon, O.-K.; Homann, O.; Wang, S.; Li, C.-M. K.
10.1101/2020.09.04.283499 — immunology — Posted on 2020-09-04
3600 Two cortical representations of voice control are differentially involved in speech fluency
Neef, N. E.; Primassin, A.; Wolff von Gudenberg, A.; Dechent, P.; Riedel, H. C.; Paulus, W.; Sommer, M.
10.1101/2020.09.04.283275 — neuroscience — Posted on 2020-09-04
3601 Genome-Wide Association Mapping of Sugarcane Yellow Leaf Virus Resistance
Pimenta, R. J. G.; Aono, A. H.; Villavicencio, R. C. B.; da Silva, C. C.; dos Anjos, I. A.; Landell, M. G. d. A.; Gonçalves, M. C.; Pinto, L. R.; de Souza, A. P.
10.1101/2020.09.04.283614 — plant biology — Posted on 2020-09-04
3603 Only SF3B1 Mutation involving K700E (And Not Other Codons), Independently Predicts Overall Survival in Myelodysplastic Syndromes
Kanagal-Shamanna, R.; Montalban-Bravo, G.; Sasaki, K.; Jabbour, E.; Bueso-Ramos, C.; Wei, Y.; Chein, K. S.; Kadia, T. M.; Ravandi, F.; Borthakur, G. M.; Soltysiak, K. A.; Daver, N. G.; Darbaniyan, F.; Routbort, M.; Patel, K.; Medeiros, L. J.; Pierce, S.; Kantarjian, H.; Garcia-Manero, G.
10.1101/2020.09.04.283598 — cancer biology — Posted on 2020-09-04
3604 Resolving the spatial and cellular architecture of lung adenocarcinoma by multi-region single-cell sequencing
Sinjab, A.; Han, G.; Kobayashi, K.; Treekitkarnmongkol, W.; Brennan, P.; Dang, M.; Hao, D.; Wang, R.; Dai, E.; Dejima, H.; Zhang, J.; Bogatenkova, E.; Sanchez-Espiridion, B.; Chang, K.; Little, D. R.; Bazzi, S.; Tran, L.; Krysan, K.; Behrens, C.; Duose, D.; Parra, E. R.; Raso, M. G.; Solis, L. M.; Fukuoka, J.; Zhang, J.; Sepesi, B.; Cascone, T.; Byers, L.; Gibbons, D. L.; Chen, J.; Moghaddam, S. J.; Ostrin, E. J.; Rosen, D. G.; Fujimoto, J.; Heymach, J. V.; Scheet, P.; Dubinett, S.; Wistuba, I. I.; Stevenson, C. S.; Spira, A. E.; Wang, L.; Kadara, H.
10.1101/2020.09.04.283739 — cancer biology — Posted on 2020-09-04
3605 PPM1D is a neuroblastoma oncogene and therapeutic target in childhood neural tumors.
Milosevic, J.; Fransson, S.; Gulyas, M.; Gallo-Oller, G.; Olsen, T. K.; Treis, D.; Wickstrom, M.; Elfman, L. H.; Sveinbjornsson, B.; Hertwig, F.; Bartenhagen, C.; Reinsbach, S.; Wilhelm, M.; Abel, F.; Javanmardi, N.; Thankaswamy-Kosalai, S.; Eissler, N.; Kock, A.; Shi, Y.; Tanino, K.; Hehir-Kwa, J. Y.; Mensenkamp, A.; Tytgat, G. A.; Kanduri, C.; Holmberg, J.; Gisselsson, D.; Molenaar, J. J.; Jongmans, M.; Fischer, M.; Kool, M.; Sakaguchi, K.; Baryawno, N.; Martinsson, T.; Johnsen, J. I.; Kogner, P.
10.1101/2020.09.04.283648 — cancer biology — Posted on 2020-09-04
3607 Surface-catalyzed SAS-6 self-assembly directs centriole formation through kinetic and structural mechanisms
Banterle, N.; Nievergelt, A. P.; de Buhr, S.; Hatzopoulos, G. N.; Brillard, C.; Andany, S.; Hübscher, T.; Sorgenfrei, F.; Schwarz, U. S.; Gräter, F.; Fantner, G. E.; Gönczy, P.
10.1101/2020.09.04.283184 — biophysics — Posted on 2020-09-04
3610 Genome Methylation Predicts Age and Longevity of Bats
Wilkinson, G. S.; Adams, D. M.; Arnold, B. D.; Ball, H. C.; Breeze, C. E.; Carter, G. G.; Cooper, L. N.; Dechmann, D. K. N.; Devanna, P. S.; Fasel, N. J.; Galazyuk, A. V.; Gunther, L.; Haghani, A.; Li, C. Z.; Lu, A.; Hurme, E.; Jones, G.; Knornschild, M.; Lattenkamp, E. Z.; Mayer, F.; Medellin, R. A.; Nagy, M.; Pope, B.; Power, M. L.; Ransome, R. D.; Reinhardt, J. A.; Teeling, E. C.; Vernes, S. C.; Zamora-Mejias, D.; Zhang, J.; Zoller, J.; Horvath, S. C.
10.1101/2020.09.04.283655 — genomics — Posted on 2020-09-04
3612 Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals
Stanzick, K.-J.; Li, Y.; Gorski, M.; Wuttke, M.; Pattaro, C.; Koettgen, A.; Stark, K. J.; Heid, I. M.; Winkler, T. W.
10.1101/2020.09.04.283713 — genetics — Posted on 2020-09-04
3613 HIV cell-to-cell spread slows evolution of drug resistance
Hunter, J.; Cele, S.; Jackson, L.; Giandhari, J.; de Oliveira, T.; Lustig, G.; Sigal, A.
10.1101/2020.09.04.283192 — evolutionary biology — Posted on 2020-09-04
3615 Extreme hyperallometry of mammalian antibacterial defenses
Downs, C. J.; Schoenle, L. A.; Oakey, S. J.; Ball, R.; Jiang, R. H.; Klasing, K. C.; Martin, L. B.
10.1101/2020.09.04.242107 — ecology — Posted on 2020-09-04
3617 Visualizing the metazoan proliferation-terminal differentiation decision in vivo
Adikes, R. C.; Kohrman, A. Q.; Martinez, M. A. Q.; Palmisano, N. J.; Smith, J. J.; Medwig-Kinney, T. N.; Min, M.; Sallee, M. D.; Ahmed, O. B.; Kim, N.; Liu, S.; Morabito, R.; Weeks, N.; Zhao, Q.; Zhang, W.; Feldman, J.; Barkoulas, M.; Pani, A. M.; Spencer, S. L.; Martin, B. L.; Matus, D. Q.
10.1101/2019.12.18.881888 — developmental biology — Posted on 2020-09-04
3619 Translation and codon usage regulate Argonaute slicer activity to trigger small RNA biogenesis
Singh, M.; Cornes, E.; Li, B.; Quarato, P.; Bourdon, L.; Dingli, F.; Loew, D.; Procaccia, S.; Cecere, G.
10.1101/2020.09.04.282863 — molecular biology — Posted on 2020-09-04
3621 Dynamics of the HD regulatory subdomain of PARP 1; substrate access and allostery in PARP activation and inhibition.
Ogden, T. E. H.; Yang, J.-C.; Schimpl, M.; Easton, L. E.; Underwood, E.; Rawlins, P. B.; McCauley, M. M.; Langelier, M.-F.; Pascal, J. M.; Embrey, K. J.; Neuhaus, D.
10.1101/2020.09.04.283309 — molecular biology — Posted on 2020-09-04
3622 Translational activity of the splicing factor SRSF1 is required for development and cilia function
Haward, F.; Maslon, M. M.; Yeyati, P. L.; Bellora, N.; Hansen, J. N.; Aitken, S.; Lawson, J.; von Kriegsheim, A.; Wachten, D.; Mill, P.; Adams, I. R.; Caceres, J. F.
10.1101/2020.09.04.263251 — molecular biology — Posted on 2020-09-04
3624 High throughput instrument to screen fluorescent proteins under two-photon excitation
Molina, R. S.; King, J.; Franklin, J.; Clack, N.; McRaven, C.; Goncharov, V.; Flickinger, D.; Svoboda, K.; Drobizhev, M.; Hughes, T. E.
10.1101/2020.09.04.283572 — neuroscience — Posted on 2020-09-04
3625 Mitochondrial, cell cycle control and neuritogenesis alterations in an iPSC-based neurodevelopmental model for schizophrenia
Zuccoli, G. S.; Nascimento, J. M.; Codo, A. C.; Moraes-Vieira, P. M.; Rehen, S. S.; Martins-de-Souza, D.
10.1101/2020.09.04.282046 — biochemistry — Posted on 2020-09-04
3626 Evolutionarily conserved chaperone-mediated proteasomal degradation of a disease-linked aspartoacylase variant
Gersing, S. K.; Wang, Y.; Gronbaek-Thygesen, M.; Kampmeyer, C.; Clausen, L.; Andreasson, C.; Stein, A.; Lindorff-Larsen, K.; Hartmann-Petersen, R.
10.1101/2020.09.04.283028 — biochemistry — Posted on 2020-09-04
3628 Proteome dynamics in persisting and resuscitating bacterial cells
Semanjski, M.; Gratani, F.; Englert, T.; Beke, V.; Nalpas, N.; Germain, E.; Gerdes, K.; Macek, B.
10.1101/2020.09.04.282723 — microbiology — Posted on 2020-09-04
3630 Single-cell analysis of chromatin silencing programs in developmental and tumor progression
Wu, S. J.; Furlan, S. N.; Mihalas, A. B.; Kaya-Okur, H.; Feroze, A. H.; Emerson, S. N.; Zheng, Y.; Carson, K.; Cimino, P. J.; Keene, C. D.; Holland, E. C.; Sarthy, J. F.; Gottardo, R.; Ahmad, K.; Henikoff, S.; Patel, A. P.
10.1101/2020.09.04.282418 — genomics — Posted on 2020-09-04
3635 starmapVR: immersive visualisation of single cell spatial omic data
Yang, A.; Yao, Y.; Fang, X.; Li, J.; Xia, Y.; Kwok, C. S. M.; Lo, M. C. K.; Siu, D. M. D.; Tsia, K. K.; Ho, J. W. K.
10.1101/2020.09.01.277079 — bioinformatics — Posted on 2020-09-04
3637 QSIPrep: An integrative platform for preprocessing and reconstructing diffusion MRI
Cieslak, M.; Cook, P. A.; He, X.; Yeh, F.-C.; Dhollander, T.; Adebimpe, A.; Aguirre, G. K.; Bassett, D. S.; Betzel, R. F.; Bourque, J.; Cabral, L.; Davatzikos, C.; Detre, J.; Earl, E.; Elliott, M. A.; Fadnavis, S.; Fair, D. A.; Foran, W.; Fotiadis, P.; Garyfallidis, E.; Giesbrecht, B.; Gur, R. C.; Gur, R. E.; Kelz, M.; Keshavan, A.; Larsen, B. S.; Luna, B.; Mackey, A. P.; Milham, M.; Oathes, D. J.; Perrone, A.; Pines, A. R.; Roalf, D. R.; Richie-Halford, A.; Rokem, A.; Sydnor, V.; Tapera, T. M.; Tooley, U. A.; Vettel, J. M.; Yeatman, J.; Grafton, S. T.; Satterthwaite, T. D.
10.1101/2020.09.04.282269 — bioinformatics — Posted on 2020-09-04
3638 Genomic divergence and differential gene expression between crustacean ecotypes across a marine thermal gradient
Emami-Khoyi, A.; Knapp, I. S.; Monsanto, D. M.; Jansen van Vuuren, B.; Toonen, R. J.; Teske, P.
10.1101/2020.09.04.282517 — genomics — Posted on 2020-09-04
3639 Whole-Genome Enrichment and Sequencing of Chlamydia trachomatis Directly from Patient Clinical Vaginal and Rectal Swabs
Bowden, K. E.; Joseph, S. J.; Cartee, J.; Ziklo, N.; Danavall, D.; Raphael, B. H.; Read, T. D.; Dean, D.
10.1101/2020.09.04.282459 — genomics — Posted on 2020-09-04
3640 Single-cell RNA-seq reveals early heterogeneity during ageing in yeast
Zhang, Y.; Wang, J.; Sang, Y.; Jin, S.; Wang, X.; Azad, G. K.; McCormick, M. A.; Kennedy, B. K.; Li, Q.; Wang, J.; Zhang, X.; Huang, Y.
10.1101/2020.09.04.282525 — genomics — Posted on 2020-09-04
3641 The oriental fruit moth genome provides insights into evolutionary adaptation of tortricid pests
Song, W.; Cao, L.-J.; Yue, L.; Guo, S.-K.; Chen, J.-C.; Gong, Y.-J.; Fan, X.-L.; Wei, S.-J.
10.1101/2020.09.04.282533 — genomics — Posted on 2020-09-04
3642 De novo virus inference and host prediction from metagenome using CRISPR spacers
Sugimoto, R.; Nishimura, L.; Ito, J.; Parrish, N. F.; Mori, H.; Kurokawa, K.; Nakaoka, H.; Inoue, I.
10.1101/2020.09.04.282665 — genomics — Posted on 2020-09-04
3644 Multimerization- and glycosylation-dependent receptor binding of SARS-CoV-2 spike proteins
Bouwman, K. M.; Tomris, I.; Turner, H. L.; van der Woude, R.; Bosman, G. P.; Herfst, S.; Rockx, B.; Haagmans, B.; Ward, A.; Boons, G.-J.; de Vries, R. P.
10.1101/2020.09.04.282558 — molecular biology — Posted on 2020-09-04
3646 Non-permissive human conventional CD1c+ dendritic cells enable trans-infection of human primary renal tubular epithelial cells and protect BK polyomavirus from neutralization
Sikorski, M.; Coulon, F.; Peltier, C.; Braudeau, C.; Garcia, A.; Giraud, M.; Autain-Renaudin, K.; Kandel-Aznar, C.; Nedellec, S.; Hulin, P.; Branchereau, J.; Veziers, J.; Gaboriaud, P.; Touze, A.; Burlaud-Gaillard, J.; Josien, R.; McIlroy, D.; Bressollette-Bodin, C.; Halary, F.
10.1101/2020.09.04.282426 — microbiology — Posted on 2020-09-04
3650 Phasic modulation of visual representations during sustained attention
van Es, M. W. J.; Marshall, T. R.; Spaak, E.; Jensen, O.; Schoffelen, J.-M.
10.1101/2020.09.04.282715 — neuroscience — Posted on 2020-09-04
3651 A SARS-CoV-2 - host proximity interactome
Samavarchi-Tehrani, P.; Abdouni, H.; Knight, J. D. R.; Astori, A.; Samson, R.; Lin, Z.-Y.; Kim, D.-K.; Knapp, J. J.; St-Germain, J.; Go, C. D.; Larsen, B.; Wong, C. J.; Cassonnet, P.; Demeret, C.; Jacob, Y.; Roth, F. P.; Raught, B.; Gingras, A.-C.
10.1101/2020.09.03.282103 — systems biology — Posted on 2020-09-04
3653 Preliminary report of preclinical efficacy and safety analysis of gamma-irradiated inactivated SARS-CoV-2 vaccine candidates, SK-01 version 1 and OZG-3861 version 1
SIR KARAKUS, G.; Tastan, C.; Dilek Kancagi, D.; Yurtsever, B.; Tumentemur, G.; Demir, S.; Turan, R. D.; Abanuz, S.; Cakirsoy, D.; Seyis, U.; Ozer, S.; Elibol, O.; Elek, M.; Ertop, G.; Arbak, S.; Acikel Elmas, M.; Hemsinlioglu, C.; Kocagoz, A. S.; Hatirnaz Ng, O.; Akyoney, S.; Sahin, I.; Ozbek, U.; Telci, D.; Sahin, F.; Yalcin, K.; Ovali, E.
10.1101/2020.09.04.277426 — immunology — Posted on 2020-09-04
3654 SARS-CoV-2 infection paralyzes cytotoxic and metabolic functions of immune cells
Singh, Y.; Trautwein, C.; Fendel, R.; Krickeberg, N.; Held, J.; Kreidenweiss, A.; Berezhnoy, G.; Bissinger, R.; Ossowski, S.; Salker, M. S.; Casadei, N.; Riess, O.; The DeCOI,
10.1101/2020.09.04.282780 — immunology — Posted on 2020-09-04
3656 Chromosome-level and haplotype-resolved genome assembly enabled by high-throughput single-cell sequencing of gamete genomes
Campoy, J. A.; Sun, H.; Goel, M.; Jiao, W.-B.; Folz-Donahue, K.; Wan, N.; Rubio, M.; Liu, C.; Kukat, C.; Ruiz, D.; Huettel, B.; Schneeberger, K.
10.1101/2020.04.24.060046 — genomics — Posted on 2020-09-04
3657 Improvements to the ARTIC multiplex PCR method for SARS-CoV-2 genome sequencing using nanopore
Tyson, J. R.; James, P.; Stoddart, D.; Sparks, N.; Wickenhagen, A.; Hall, G.; Choi, J. H.; Lapointe, H.; Kamelian, K.; Smith, A. D.; Prystajecky, N.; Goodfellow, I.; Wilson, S. J.; Harrigan, R.; Snutch, T. P.; Loman, N. J.; Quick, J.
10.1101/2020.09.04.283077 — genomics — Posted on 2020-09-04
3658 Genomic diversity and evolution of coronavirus (SARS-CoV-2) in France from 309 COVID-19-infected patients
Levasseur, A.; Delerce, J.; Caputo, A.; Brechard, L.; Colson, P.; Lagier, J.-C.; Fournier, P.-E.; Raoult, D.
10.1101/2020.09.04.282616 — genomics — Posted on 2020-09-04
3662 EPAC regulates von Willebrand factor secretion from endothelial cells in a PI3K/eNOS-dependent manner during inflammation
Xiao, J.; Zhang, B.; Su, Z.; Liu, Y.; Shelite, T. R.; Chang, Q.; Wang, P.; Bukreyev, A.; Soong, L.; Jin, Y.; Ksiazek, T.; Gaitas, A.; Rossi, S. L.; Zhou, J.; Laposata, M.; Saito, T. B.; Gong, B.
10.1101/2020.09.04.282806 — cell biology — Posted on 2020-09-04
3663 Shulin packages axonemal outer dynein arms for ciliary targeting
Mali, G. R.; Abid Ali, F.; Lau, C. K.; Begum, F.; Skehel, M.; Carter, A. P.
10.1101/2020.09.04.282897 — molecular biology — Posted on 2020-09-04
3664 Armeniaspirols inhibit the AAA+ proteases ClpXP and ClpYQ leading to cell division arrest in Gram-positive bacteria
Labana, P.; Dornan, M. H.; Lafreniere, M.; Czarny, T. L.; Brown, E. D.; Pezacki, J. P.; Boddy, C.
10.1101/685669 — microbiology — Posted on 2020-09-04
3665 Hue tuning curves in V4 change with visual context
Benjamin, A. S.; Ramkumar, P.; Fernandes, H.; Smith, M. A.; Kording, K. P.
10.1101/780478 — neuroscience — Posted on 2020-09-04
3666 fruitless mutant male mosquitoes gain attraction to human odor
Basrur, N. S.; De Obaldia, M. E.; Morita, T.; Herre, M.; von Heynitz, R. K.; Tsitohay, Y. N.; Vosshall, L. B.
10.1101/2020.09.04.282434 — neuroscience — Posted on 2020-09-04
3671 Obesity-associated lipidomic remodeling of the adrenal gland indicates an important role of the FADS2-arachidonic acid axis in adrenocortical hormone production
Witt, A.; Mirtschink, P.; Palladini, A.; Mateska, I.; Abdelmegeed, H.; Grzybek, M.; Wielockx, B.; Peitzsch, M.; Coskun, U.; Chavakis, T.; Alexaki, V. I.
10.1101/2020.09.04.282905 — cell biology — Posted on 2020-09-04
3672 A conserved choreography of mRNAs at centrosomes reveals a localization mechanism involving active polysome transport
Safieddine, A.; Coleno, E.; Traboulsi, A.-M.; Kwon, O. S.; Lionneton, F.; Georget, V.; Robert, M.-C.; Gostan, T.; Lecellier, C.; Salloum, S.; Chouaib, R.; Pichon, X.; Le Hir, H.; Zibara, K.; Peter, M.; Bertrand, E.
10.1101/2020.09.04.282038 — cell biology — Posted on 2020-09-04
3673 A Harmonized Atlas of Spinal Cord Cell Types and Their Computational Classification
Russ, D. E.; Patterson Cross, R. B.; Li, L.; Koch, S. C.; Matson, K. J. E.; Levine, A.
10.1101/2020.09.03.241760 — neuroscience — Posted on 2020-09-04
3674 Beyond Shielding: The Roles of Glycans in SARS-CoV-2 Spike Protein
Casalino, L.; Gaieb, Z.; Goldsmith, J.; Hjorth, C. K.; Dommer, A. C.; Harbison, A. M.; Fogarty, C. A.; Barros, E. P.; Taylor, B. C.; McLellan, J. S.; Fadda, E.; Amaro, R. E.
10.1101/2020.06.11.146522 — biophysics — Posted on 2020-09-04
3675 The immune vulnerability landscape of the 2019 Novel Coronavirus, SARS-CoV-2
Zhu, J.; Kim, J.; Xiao, X.; Wang, Y.; Luo, D.; Chen, R.; Xu, L.; Zhang, H.; Moise, L.; Gutierrez, A.; De Groot, A. S.; Xiao, G.; Schoggins, J.; Zhan, X.; Wang, T.; Xie, Y.
10.1101/2020.02.08.939553 — bioinformatics — Posted on 2020-09-04
3677 Drosophila melanogaster as a model host to study arbovirus vector interaction
Paingankar, M. S.; Gokhale, M. D.; Deobagkar, D. D.; Deobagkar, D. N.
10.1101/2020.09.03.282350 — zoology — Posted on 2020-09-04
3690 The tricuspid valve also maladapts: A multiscale study in sheep with biventricular heart failure
Meador, W. D.; Mathur, M.; Sugerman, G. P.; Malinowski, M.; Jazwiec, T.; Wang, X.; Lacerda, C. M.; Timek, T. A.; Rausch, M. K.
10.1101/2020.09.03.278515 — bioengineering — Posted on 2020-09-04
3697 Fast and inexpensive whole genome sequencing library preparation from intact yeast cells
Vonesch, S. C.; Li, S.; Szu Tu, C.; Hennig, B. P.; Dobrev, N.; Steinmetz, L. M.
10.1101/2020.09.03.280990 — genomics — Posted on 2020-09-04
3700 Inferring number of populations and changes in connectivity under the n-island model
Arredondo Soto, A.; Mourato, B.; Nguyen, K.; Boitard, S.; Rodriguez Valcarce, W. R.; Nous, C.; Mazet, O.; Chikhi, L.
10.1101/2020.09.03.282251 — evolutionary biology — Posted on 2020-09-04
3702 Mammalian ANP32A and ANP32B proteins drive alternative avian influenza virus polymerase adaptations
Peacock, T. P.; Sheppard, C. M.; Staller, E.; Frise, R.; Swann, O. C.; Goldhill, D.; Long, J. S.; Barclay, W. S.
10.1101/2020.09.03.282384 — microbiology — Posted on 2020-09-04
3706 Bacterial Peptidoglycan Fragments Deferentially Regulate Innate Immune Signaling
Bersch, K. L.; DeMeester, K. E.; Zagani, R.; Wodzanowski, K. A.; Reinecker, H.-C.; Grimes, C. L.
10.1101/2020.09.03.278705 — immunology — Posted on 2020-09-04
3707 Oxidized Lipids and CD36-Mediated Lipid Peroxidation in CD8 T Cells Suppress Anti-Tumor Immune Responses
Xu, S.; Chaudhary, O.; Rodriguez-Morales, P.; Sun, X.; Zappasodi, R.; Xu, Z.; Pinto, A. F. M.; Williams, A.; Chen, D.; Low, J. S.; Farsakoglu, Y.; Tang, W.; Wang, H.; Varanasi, S. K.; McDonald, B.; Tripple, V.; Downes, M.; Evans, R. M.; Abumrad, N. A.; Merghoub, T.; Wolchok, J. D.; Shokhirev, M. N.; Ho, P.-C.; Witztum, J. L.; Emu, B.; Cui, G.; Kaech, S. M.
10.1101/2020.09.03.281691 — immunology — Posted on 2020-09-04
3708 Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration
van Olst, L.; Rodriguez-Mogeda, C.; Picon-Munoz, C.; Kiljan, S.; James, R. E.; Kamermans, A.; van der Pol, S. M. A.; Knoop, L.; Drost, E.; Franssen, M.; Schenk, G.; Geurts, J. J. G.; Amor, S.; Mazarakis, N. D.; van Horssen, J.; de Vries, H. E.; Reynolds, R.; Witte, M. E.
10.1101/2020.09.03.281543 — neuroscience — Posted on 2020-09-04
3709 GTPBP1 resolves paused ribosomes to maintain neuronal homeostasis
Terrey, M.; Adamson, S. I.; Gibson, A. L.; Deng, T.; Ishimura, R.; Chuang, J. H.; Ackerman, S. L.
10.1101/2020.09.03.281675 — neuroscience — Posted on 2020-09-04
3710 Cingulo-Opercular Control Network Supports Disused Motor Circuits in Standby Mode
Newbold, D. J.; Gordon, E. M.; Laumann, T. O.; Montez, D. F.; Seider, N. A.; Gross, S. J.; Zheng, A.; Nielsen, A. N.; Hoyt, C. R.; Hampton, J. M.; Ortega, M.; Adeyemo, B.; Miller, D. B.; Van, A. N.; Marek, S.; Schlaggar, B. L.; Carter, A. R.; Kay, B. P.; Greene, D. J.; Raichle, M. E.; Petersen, S. E.; Snyder, A. Z.; Dosenbach, N. U. F.
10.1101/2020.09.03.275479 — neuroscience — Posted on 2020-09-04
3712 Novel Model of Reversible Vestibular Syndrom Induced by Optogenetic Stimulation
Montardy, Q.; Mengxia, W.; Yi, T.; Liu, X.; Zheng, Z.; Besnard, S.; Tighilet, B.; Chabbert, C.; Wang, L.
10.1101/2020.09.03.281980 — neuroscience — Posted on 2020-09-04
3714 Multimodal imaging brain markers in early adolescence are linked with a physically active lifestyle
Salvan, P.; Wassenaar, T.; Wheatley, C.; Beale, N.; Cottaar, M.; Papp, D.; Bastiani, M.; Fitzgibbon, S.; Duff, E.; Andersson, J.; Winkler, A. M.; Douaud, G.; Nichols, T. E.; Smith, S.; Dawes, H.; Johansen-Berg, H.
10.1101/2020.09.03.269571 — neuroscience — Posted on 2020-09-04
3716 Retromer Combinatorials for Gene-Therapy Across a Spectrum of Neurological Diseases
Qureshi, Y. H.; Patel, V. M.; Kannan, S.; Waksal, S. D.; Petsko, G. A.; Small, S. A.
10.1101/2020.09.03.282327 — neuroscience — Posted on 2020-09-04
3718 Redundancy Circuits of the Commissural Pathways in Human and Rhesus Macaque Brains
Ghulam-Jelani, Z.; Barrios-Martinez, J.; Eguiluz-Melendez, A.; Gomez, R.; Anania, Y.; Yeh, F.-c.
10.1101/2020.09.03.281931 — neuroscience — Posted on 2020-09-04
3722 Serum metabolomic biomarkers of perceptual speed in cognitively normal and mildly impaired subjects with fasting state stratification
Borkowski, K.; Taha, A. Y.; Pedersen, T. L.; De Jager, P. L.; Bennett, D. A.; Kaddurah-Daouk, R.; Newman, J. W.
10.1101/2020.09.03.282343 — pathology — Posted on 2020-09-04
3723 Sex-dependent pathways in hepatocarcinogenesis triggered by deregulated cholesterol synthesis
Rozman, D.; Cokan, K. B.; Urlep, Z.; Lorbek, G.; Soja, M. M.; Skubic, C.; Perse, M.; Jeruc, J.; Juvan, P.; Rezen, T.
10.1101/2020.09.03.280974 — cancer biology — Posted on 2020-09-04
3725 A fully defined pluripotent stem cell derived multi-liver-cell model for steatohepatitis and fibrosis
Gautam, M. K.; Toprakhisar, B.; Van Haele, M.; Antoranz, A.; Boon, R.; Chesnais, F.; De Smedt, J.; Idoype, T. I.; Canella, M.; Tilliole, P.; De Boeck, J.; Tricot, T.; Bajaj, M.; Ranga, A.; Bosisio, F. M.; Roskams, T.; van Grunsven, L. A.; Verfaillie, C. M.
10.1101/2020.09.03.280883 — bioengineering — Posted on 2020-09-04
3726 Subcutaneous nanotherapy repurposes the immunosuppressive mechanism of rapamycin to enhance allogeneic islet graft viability
Burke, J.; Zhang, X.; Bobbala, S.; Frey, M.; Fuentes, C.; Haddad, H.; Allen, S.; Richardson, R.; Amaral, L.; Ameer, G.; Scott, E. A.
10.1101/2020.09.03.281923 — bioengineering — Posted on 2020-09-04
3728 Genome sequence of the oyster mushroom Pleurotus ostreatus strain PC9
Lee, Y.-Y.; Vidal-Diez de Ulzurrun, G.; Schwarz, E. M.; Stajich, J. E.; Hsueh, Y.-P.
10.1101/2020.09.03.281683 — genomics — Posted on 2020-09-04
3732 Neuronal perception of the social environment intergenerationally controls germline development and generation time in C. elegans
Perez, M. F.; Shamalnasab, M.; Mata-Cabana, A.; Della Valle, S.; Olmedo, M.; Francesconi, M.; Lehner, B.
10.1101/2020.09.03.279158 — genetics — Posted on 2020-09-04
3737 Faster model updating in autism during early sensory processing
Goris, J.; Braem, S.; Van Herck, S.; Deschrijver, E.; Wiersema, J. R.; Paton, B.; Brass, M.; Todd, J.
10.1101/2020.09.04.279471 — neuroscience — Posted on 2020-09-04
3738 All-Trans Retinoic Acid induces synaptic plasticity in human cortical neurons
Lenz, M.; Kruse, P.; Eichler, A.; Muellerleile, J.; Straehle, J.; Jedlicka, P.; Beck, J.; Deller, T.; Vlachos, A.
10.1101/2020.09.04.267104 — neuroscience — Posted on 2020-09-04
3740 TRIM37 prevents formation of centriolar protein assemblies by regulating Centrobin stability
Gönczy, P.; Balestra, F. R.; Wolf, B.; Dominguez-Calvo, A.; Buff, A.; Averink, T.; Lipsanen-Nyman, M.; Busso, C.; Huertas, P.; Rios, R. M.
10.1101/2020.09.03.281097 — cell biology — Posted on 2020-09-04
3741 Low immunogenicity of malaria pre-erythrocytic stages can be overcome by vaccination
Mueller, K.; Gibbins, M. P.; Roberts, M.; Reyes-Sandoval, A.; Hill, A.; Draper, S.; Matuschewski, K.; Silvie, O.; Hafalla, J.
10.1101/2020.09.03.281238 — immunology — Posted on 2020-09-04
3744 Depsipeptide nucleic acids: prebiotic formation, oligomerization, and self-assembly of a new candidate proto-nucleic acid
Hud, N. V.; Fialho, D. M.; Karunakaran, S.; Greeson, K. W.; Martinez, I.; Schuster, G. B.; Krishnamurthy, R.
10.1101/2020.09.01.278838 — biochemistry — Posted on 2020-09-04
3747 MSK-mediated phosphorylation of Histone 3 Ser28 couples MAPK signaling with early gene induction and cardiac hypertrophy
Robinson, E. L.; Drawnel, F. M.; Mehdi, S.; Archer, C. R.; Liu, W.; Okkenhaug, H.; Alkass, K.; Aronsen, J. M.; Nagaraju, C. K.; Sjaastad, I.; Sipido, K. R.; Bergmann, O.; Arthur, J. S. C.; Wang, X.; Roderick, H. L.
10.1101/2020.07.28.224832 — molecular biology — Posted on 2020-09-04
3750 Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations
Rees, E.; Creeth, H.; Hwu, H.-G.; Chen, W. J.; Tsuang, M.; Glatt, S.; Rey, R.; Kirov, G.; Walters, J.; Holmans, P.; Owen, M.; O'Donovan, M.
10.1101/2020.09.02.279265 — genetics — Posted on 2020-09-04
3751 Mycobacterium tuberculosis complex lineage 5 exhibits high levels of within-lineage genomic diversity and differing gene content compared to the type strain H37Rv
Sanoussi, C. N.; Coscolla, M.; Ofori-Anyinam, A. B.; Otchere, I. D.; Antonio, M.; Niemann, S.; Parkhill, J.; Harris, S.; Yeboah-Manu, D.; Gagneux, S.; Rigouts, L.; Affolabi, D.; de Jong, B. C.; Meehan, C. J.
10.1101/2020.06.22.164186 — genetics — Posted on 2020-09-04
3753 Dendritic localization of mRNA in Drosophila Mushroom Body Output Neurons
Mitchell, J.; Smith, C. S.; Titlow, J.; Otto, N.; van Velde, P.; Booth, M.; Davis, I.; Waddell, S.
10.1101/2020.09.03.281899 — neuroscience — Posted on 2020-09-03
3760 The p97-UBXN1 complex regulates aggresome formation
Mukkavalli, S.; Klickstein, J. A.; Ortiz, B.; Juo, P.; Raman, M.
10.1101/2020.09.03.281766 — cell biology — Posted on 2020-09-03
3762 Essentiality of c-di-AMP in Bacillus subtilis: Bypassing mutations converge in potassium and glutamate homeostasis
Krüger, L.; Herzberg, C.; Rath, H.; Pedreira, T.; Poehlein, A.; Gundlach, J.; Daniel, R.; Völker, U.; Mäder, U.; Stülke, J.
10.1101/2020.09.03.280651 — microbiology — Posted on 2020-09-03
3763 Alcohol dependence promotes systemic IFN-γ and IL-17 responses in mice
Frank, K.; Abeynaike, S.; Nikzad, R.; Patel, R. R.; Roberts, A. J.; Roberto, M.; Paust, S.
10.1101/2020.09.03.280735 — immunology — Posted on 2020-09-03
3764 Blocking IL-10 signaling with soluble IL-10 receptor restores specific lymphoproliferative response in dogs with leishmaniasis caused by Leishmania infantum
Sa Oliveira, G. G.; Santos, C. O.; Costa, S. F.; Souza, F. S.; Mendes, J. M. F.; Pinheiro, C. G. M.; Moreira, D. R. M.; Silva, L. K.; Lima, V. M. F.
10.1101/2020.09.02.280610 — immunology — Posted on 2020-09-03
3765 Differences in Chemo-signaling Compound-Evoked Brain Activity in Male and Female Young Adults: A Pilot Study in the Role of Sexual Dimorphism in Olfactory Chemo-Signaling
Ottesen, T.; Davis, K. C.; Hobbs, L. K.; Muncy, N. M.; Stevens, N. M.; Anderson, M.; Johnson, P.; Doxey, C. R.; Richter, K.; Wang, H.; Hartley, R.; Kirwan, C. B.; Wisco, J. J.
10.1101/2020.09.03.280685 — neuroscience — Posted on 2020-09-03
3767 Single-vessel cerebral blood flow fMRI to map blood velocity by phase-contrast imaging
Chen, X.; Jiang, Y.; Choi, S.; Pohmann, R.; Scheffler, K.; Kleninfeld, D.; Yu, X.
10.1101/2020.09.03.280636 — neuroscience — Posted on 2020-09-03
3770 Combining Natural Language Processing and Metabarcoding to Reveal Pathogen-Environment Associations
Molik, D. C.; Tomlinson, D.; Davitt, S.; Morgan, E. L.; Roche, B.; Meyers, N.; Pfrender, M. E.
10.1101/2020.09.02.280578 — bioinformatics — Posted on 2020-09-03
3772 Emergence of stable motifs in consumer-resource communities
Amarasekare, P.; Brose, U.; Chase, J.; Knight, T.; Clark, A.
10.1101/2020.09.03.280644 — ecology — Posted on 2020-09-03
3774 Identification, Localization and Expression of NHE Isoforms in the Alveolar Epithelial Cells
Azzam, Z. S.; Kinaneh, S.; Knany, Y.; Khoury, E. E.; Ismael-Badarneh, R.; Hammoud, S.; Berger, G.; Abassi, Z. A.
10.1101/2020.09.03.280677 — cell biology — Posted on 2020-09-03
3775 Antibiotics and the developing intestinal microbiome, metabolome and inflammatory environment: a randomized trial of preterm infants
Russell, J. T.; Ruoss, J. L.; de la Cruz, D.; Li, N.; Bazacliu, C.; Patton, L.; Lobean McKinley, K.; Garrett, T. J.; Polin, R. A.; Triplett, E. W.; Neu, J.
10.1101/2020.04.20.052142 — microbiology — Posted on 2020-09-03
3776 Comparative genomics of Clostridium species associated with vacuum-packed meat spoilage.
Palevich, N.; Palevich, F. P.; Maclean, P. H.; Altermann, E.; Gardner, A.; Burgess, S.; Mills, J.; Brightwell, G.
10.1101/2020.09.03.282111 — microbiology — Posted on 2020-09-03
3777 Activated iPSC-microglia from C9orf72 ALS/FTD patients exhibit endosomal-lysosomal dysfunction
Lorenzini, I.; Alsop, E.; Levy, J.; Gittings, L. M.; Rabichow, B. E.; Lall, D.; Moore, S.; Bustos, L.; Pevey, R.; Burciu, C.; Saul, J.; McQuade, A.; Tzioras, M.; Mota, T. A.; Logemann, A.; Rose, J.; Almeida, S.; Gao, F.-B.; Bowser, R.; Spires-Jones, T. L.; Blurton-Jones, M.; Gendron, T. F.; Baloh, R. H.; Van Keuren-Jensen, K.; Sattler, R.
10.1101/2020.09.03.277459 — neuroscience — Posted on 2020-09-03
3778 Single-cell Characterization of Acute Myeloid Leukemia and its Microenvironment Following PD-1 Blockade Based Therapy
Abbas, H. A.; Hao, D.; Tomczak, K.; Baroodia, P.; Im, J.; Reville, P. K.; Alaniz, Z.; Wang, W.; Wang, R.; Wang, F.; Al-Atrash, G.; Takahashi, K.; Ning, J.; Ding, M.; Matthews, J.; Little, L.; Zhang, J.; Basu, S.; Konopleva, M.; Garcia-Manero, G.; Green, M. R.; Sharma, P.; Allison, J.; Kornblau, S.; Rai, K.; Wang, L.; Daver, N.; Futreal, A.
10.1101/2020.09.03.278309 — cancer biology — Posted on 2020-09-03
3779 HPM Live μ for full CLEM workflow
Heiligenstein, X.; de Beer, M.; Heiligenstein, J.; Eyraud, F.; Manet, L.; Schmitt, F.; Lamers, E.; Lindenau, J.; Kea-te Lindert, M.; Salamero, J.; Raposo, G.; sommerdijk, N.; Belle, M.; Akiva, A.
10.1101/2020.09.03.281956 — biophysics — Posted on 2020-09-03
3781 Inherently confinable split-drive systems in Drosophila
Terradas, G.; Buchman, A. B.; Bennett, J. B.; Shriner, I.; Marshall, J. M.; Akbari, O. S.; Bier, E.
10.1101/2020.09.03.282079 — genetics — Posted on 2020-09-03
3782 Role of Epigenetics in Unicellular to Multicellular Transition in Dictyostelium
Wang, S. Y.; Pollina, E. A.; Wang, I. H.; Bushnell, H.; Takashima, K.; Fritsche, C.; Sabin, G.; Greer, P. L.; Greer, E. L.
10.1101/2020.09.03.282152 — genetics — Posted on 2020-09-03
3783 Hybrid seed incompatibility in Capsella is connected to chromatin condensation defects in the endosperm
Dziasek, K.; Simon, L.; Lafon Placette, C.; Laenen, B.; Wärdig, C.; Juan Santos-Gonzalez, J.; Slotte, T.; Köhler, C.
10.1101/2020.09.03.281048 — evolutionary biology — Posted on 2020-09-03
3786 Transcriptome-Wide Off-Target Effects of Steric-Blocking Oligonucleotides
Holgersen, E. M.; Gandhi, S.; Zhou, Y.; Kim, J.; Vaz, B.; Bogojeski, J.; Bugno, M.; Shalev, Z.; Cheung-Ong, K.; Goncalves, J.; O'Hara, M.; Sun, M.; Kakaradov, B.; Delong, A.; Merico, D.; Deshwar, A. G.
10.1101/2020.09.03.281667 — molecular biology — Posted on 2020-09-03
3787 A single nuclei transcriptomic analysis of the Atlantic salmon gill through smoltification and seawater transfer
West, A. C.; Mizoro, Y.; Wood, S. H.; Ince, L.; Iversen, M.; Jorgensen, E. H.; Nome, T.; Sandve, S. R.; Loudon, A. S. I.; Hazlerigg, D. G.
10.1101/2020.09.03.281337 — molecular biology — Posted on 2020-09-03
3788 Azetidines kill Mycobacterium tuberculosis without detectable resistance by blocking mycolate assembly.
Lanne, A. B.; Cui, Y.; Browne, E.; Craven, P. G. E.; Cundy, N. J.; Coltman, N. J.; Dale, K.; Feula, A.; Frampton, J.; Goff, A.; Hama Salih, M. A.; Lang, X.; Li, X.; Moon, C. W.; Morton, M.; Pascoe, J.; Peng, X.; Portman, V.; Press, C.; Schulz-Utermoehl, T.; Tortorella, M.; Tu, Z.; Underwood, Z. E.; Wang, C.; Yoshizawa, A.; Zhang, T.; Waddell, S. J.; Bacon, J.; Neagoie, C.; Fossey, J. S.; Alderwick, L. J.
10.1101/2020.09.03.281170 — microbiology — Posted on 2020-09-03
3790 A Single Dose of Self-Transcribing and Replicating RNA Based SARS-CoV-2 Vaccine Produces Protective Adaptive Immunity In Mice
de Alwis, R. M.; Gan, E. S.; Chen, S.; Leong, Y. S.; Tan, H. C.; Zhang, S. L.; Yau, C.; Matsuda, D.; Allen, E.; Hartman, P.; Park, J.; Alayyoubi, M.; Bhaskaran, H.; Dukanovic, A.; Bao, B.; Clemente, B.; Vega, J.; Roberts, S.; Gonzalez, J. A.; Sablad, M.; Yelin, R.; Taylor, W.; Tachikawa, K.; Parker, S.; Karmali, P.; Davis, J.; Sullivan, S. M.; Hughes, S. G.; Chivukula, P.; Ooi, E. E.
10.1101/2020.09.03.280446 — immunology — Posted on 2020-09-03
3791 CD4 Effectors Need to Recognize Antigen Locally to Become Cytotoxic CD4 and Follicular Helper T Cells
Devarajan, P.; Vong, A. M.; Castonguay, C. H.; Bautista, B. L.; Jones, M. C.; Kugler-Umana, O.; Kelly, K. A.; Swain, S. L.
10.1101/2020.09.03.281998 — immunology — Posted on 2020-09-03
3793 The microbiome affects liver sphingolipids and plasma fatty acids in a murine model of the Western diet based on soybean oil
Di Rienzi, S.; Johnson, E.; Waters, J. L.; Kennedy, E. A.; Jacobson, J.; Lawrence, P.; Wang, D. H.; Worgall, T. S.; Brenna, J. T.; Ley, R. E.
10.1101/2020.09.03.281626 — systems biology — Posted on 2020-09-03
3794 Is there a role for the RNA-binding protein LARP1 in β-cells?
Werneck de Castro, J. P.; Pecanha, F. L. M.; Silvestre, D. H.; Bernal-Mizrachi, E.
10.1101/2020.09.03.281832 — physiology — Posted on 2020-09-03
3797 qFit 3: Protein and ligand multiconformer modeling for X-ray crystallographic and single-particle cryo-EM density maps
Riley, B. T.; Wankowicz, S. A.; de Oliveira, S. H. P.; van Zundert, G. C. P.; Hogan, D.; Fraser, J. S.; Keedy, D. A.; van den Bedem, H.
10.1101/2020.09.03.280222 — biophysics — Posted on 2020-09-03
3799 Structural Insights into Photoactivation of Plant Cryptochrome-2
Palayam, M.; Ganapathy, J.; Guercio, A. M.; Tal, L.; Deck, S. L.; Shabek, N.
10.1101/2020.07.30.227371 — biochemistry — Posted on 2020-09-03
3800 SUMO Modifies GβL and Mediates mTOR Signaling
Park, S. L. L.; Ramirez Jarquin, U. N.; Shahani, N.; Rivera, O.; Sharma, M.; McManus, F. P.; Thibault, P.; Subramaniam, S.
10.1101/2020.09.03.281881 — biochemistry — Posted on 2020-09-03
3801 A highly rifampicin resistant Mycobacterium tuberculosis strain emerging in Southern Brazil
Rossetti, M. L.; da Silva, P. E. A.; Salvato, R. S.; Reis, A. J.; Schiefelbein, S. H.; von Groll, A.; Barcellos, R.; Maschmann, R.; Esteves, L.; Spies, F.; Trespach, R.; Dalla Costa, E. R.; Amorim, H.
10.1101/2020.09.03.282194 — genomics — Posted on 2020-09-03
3802 Twinfilin1 controls lamellipodial protrusive activity and actin turnover during vertebrate gastrulation
Devitt, C.; Lee, C.; Cox, R.; Papoulas, O.; Alvarado, J.; Marcotte, E.; Wallingford, J. B.
10.1101/2020.09.03.281659 — cell biology — Posted on 2020-09-03
3804 Chromatin-associated protein complexes link DNA base J and transcription termination in Leishmania
Jensen, B. C.; Phan, I. Q.; McDonald, J. R.; Sur, A.; Gillespie, M. A.; Ranish, J. A.; Parsons, M.; Myler, P. J.
10.1101/2020.05.26.117721 — molecular biology — Posted on 2020-09-03
3805 Development of SARS-CoV-2 Nucleocapsid Specific Monoclonal Antibodies
Terry, J. S.; Anderson, L. B.; Scherman, M. S.; McAlister, C. E.; Perera, R.; Schountz, T.; Geiss, B. J.
10.1101/2020.09.03.280370 — microbiology — Posted on 2020-09-03
3808 Longitudinal single-cell immune profiling revealed distinct innate immune response in asymptomatic COVID-19 patients
Zhao, X.-N.; You, Y.; Wang, G.-L.; Gao, H.-X.; Cui, X.-M.; Duan, L.-J.; Zhang, S.-B.; Wang, Y.-L.; Yao, L.; Li, L.; Lu, J.-H.; Wang, H.-B.; Fan, J.-F.; Zheng, H.-W.; Dai, E.-H.; Tian, L.; Ma, M.-J.
10.1101/2020.09.02.276865 — immunology — Posted on 2020-09-03
3809 Brain/MINDS Beyond Human Brain MRI Study: Multi-Site Harmonization for Brain Disorders Throughout the Lifespan
Koike, S.; Tanaka, S.; Okada, T.; Aso, T.; Asano, M.; Maikusa, N.; Morita, K.; Okada, N.; Fukunaga, M.; Uematsu, A.; Togo, H.; Miyazaki, A.; Murata, K.; Urushibata, Y.; Autio, J. A.; Ose, T.; Yoshiomoto, J.; Araki, T.; Glasser, M. F.; Van Essen, D. C.; Murayama, M.; Sadato, N.; Kawato, M.; Kasai, K.; Okamoto, Y.; Hanakawa, T.; Hayashi, T.; Brain/MINDS Beyond Human Brain MRI Group,
10.1101/2020.05.05.076273 — neuroscience — Posted on 2020-09-03
3812 Viral integration transforms chromatin to drive oncogenesis
Karimzadeh, M.; Arlidge, C.; Rostami, A.; Lupien, M.; Bratman, S. V.; Hoffman, M. M.
10.1101/2020.02.12.942755 — cancer biology — Posted on 2020-09-03
3815 Zooplankton community beta diversity in an Amazonian floodplain lake
Gomes, L. F.; Gomes, A. C. A. M.; de Souza, C. A.; Pereira, H. R.; Bonnet, M.-P.; Vieira, L. C. G.
10.1101/2020.07.31.231241 — ecology — Posted on 2020-09-03
3820 Intranasal Vaccination with a Lentiviral Vector Strongly Protects against SARS-CoV-2 in Mouse and Golden Hamster Preclinical Models
Ku, M.-W.; Bourgine, M.; Authie, P.; Lopez, J.; Nemirov, K.; Moncoq, F.; Noirat, A.; Vesin, B.; Nevo, F.; Blanc, C.; Souque, P.; Tabbal, H.; Simon, E.; Le Dudal, M.; Guinet, F.; Fiette, L.; Mouquet, H.; Anna, F.; Martin, A.; Escriou, N.; Majlessi, L.; Charneau, P.
10.1101/2020.07.21.214049 — immunology — Posted on 2020-09-03
3822 Simeprevir suppresses SARS-CoV-2 replication and synergizes with remdesivir
Lo, H. S.; Hui, K. P. Y.; Lai, H.-M.; Khan, K. S.; Kaur, S.; Huang, J.; Li, Z.; Chan, A. K. N.; Cheung, H. H.-Y.; Ng, K. C.; Ho, J. C. W.; Chen, Y. W.; Ma, B.; Cheung, P. M.-H.; Shin, D.; Wang, K.; Lee, M.-H.; Selisko, B.; Eydoux, C.; Guillemot, J.-C.; Canard, B.; Wu, K.-P.; Dikic, I.; Liang, P.-H.; Zuo, Z.; Chan, F. K. L.; Hui, D. S. C.; Mok, V. C. T.; Wong, K.-B.; Ko, H.; Aik, W. S.; Chan, M. C. W.; Ng, W.-L.
10.1101/2020.05.26.116020 — microbiology — Posted on 2020-09-03
3824 PhosR enables processing and functional analysis of phosphoproteomic data
Kim, H. J.; Kim, T.; Hoffman, N.; Xiao, D.; James, D. E.; Humphrey, S.; Yang, P.
10.1101/2020.08.31.276329 — systems biology — Posted on 2020-09-03
3828 Deficient spermiogenesis in mice lacking Rlim
Wang, F.; Gervasi, M. G.; Boskovic, A.; Sun, F.; Rinaldi, V.; Yu, J.; Wallingford, M.; Tourzani, D.; Mager, J.; Zhu, L.; Rando, O.; Visconti, P.; Strittmatter, L.; Bach, I.
10.1101/2020.08.31.275248 — developmental biology — Posted on 2020-09-03
3830 Proliferation genes repressed by TGF-β are downstream of Slug/Snail2 in normal bronchial epithelial progenitors and are deregulated in COPD
Ben Brahim, C.; Courageux, C.; Jolly, A.; Ouine, B.; Cartier, A.; de la Grange, P.; de Koning, L.; Leroy, P.
10.1101/674127 — cell biology — Posted on 2020-09-03
3831 Potent neutralization of clinical isolates of SARS-CoV-2 D614 and G614 variants by a monomeric, sub-nanomolar affinity Nanobody.
Valenzuela Nieto, G. E.; Jara, R.; Watterson, D.; Modhiran, N.; Amarilla, A. A.; Himelreichs, J.; Khromykh, A. A.; Salinas, C.; Pinto, T.; Cheuquemilla, Y.; Margolles, Y.; Lopez Gonzalez del Rey, N.; Miranda Chacon, Z.; Cuevas, A.; Berking, A.; Deride, C.; Gonzalez-Moraga, S.; Mancilla, H.; Maturana, D.; Langer, A.; Toledo, J. P.; Müller, A.; Uberti, B.; Krall, P.; Ehrenfeld, P.; Blesa, J.; Chana-Cuevas, P.; Rehren, G.; Schwefel, D.; Fernandez, L. A.; Rojas-Fernandez, A.
10.1101/2020.06.09.137935 — molecular biology — Posted on 2020-09-03
3832 EslB is required for cell wall biosynthesis and modification in Listeria monocytogenes
Rismondo, J.; Schulz, L. M.; Yacoub, M.; Wadhawan, A.; Hoppert, M.; Dionne, M. S.; Gründling, A.
10.1101/2020.02.03.932061 — microbiology — Posted on 2020-09-03
3835 Metabolism modulates global synchrony in the aging brain
Weistuch, C.; Mujica-Parodi, L. R.; Amgalan, A.; Dill, K. A.
10.1101/2020.04.17.047233 — neuroscience — Posted on 2020-09-03
3837 Ligand Sensing Enhances Bacterial Flagellar Motor Output via Stator Recruitment
Naaz, F.; Agrawal, M.; Chakraborty, S.; Tirumkudulu, M. S.; Venkatesh, K. V.
10.1101/2020.04.20.050906 — biophysics — Posted on 2020-09-03
3840 The global landscape of SARS-CoV-2 genomes, variants, and haplotypes in 2019nCoVR
Song, S.; Ma, L.; Zou, D.; Tian, D.; Li, C.; Zhu, J.; Chen, M.; Wang, A.; Ma, Y.; Li, M.; Teng, X.; Cui, Y.; Duan, G.; Zhang, M.; Jin, T.; Shi, C.; Du, Z.; Zhang, Y.; Liu, C.; Li, R.; Zeng, J.; Hao, L.; Jiang, S.; Chen, H.; Han, D.; Xiao, J.; Zhang, Z.; Zhao, W.; Xue, Y.; Bao, Y.
10.1101/2020.08.30.273235 — genomics — Posted on 2020-09-03
3842 Migration without interbreeding: evolutionary history of a highly selfing Mediterranean grass inferred from whole genomes
Stritt, C.; Gimmi, E. L.; Wyler, M.; Bakali, A. H.; Skalska, A.; Hasterok, R.; Mur, L. A. J.; Pecchioni, N.; Roulin, A. C.
10.1101/2020.09.03.280842 — evolutionary biology — Posted on 2020-09-03
3843 On demand MyD88 oligomerization is controlled by IRAK4 during Myddosome signaling
Deliz-Aguirre, R.; Cao, F.; Gerpott, F. H. U.; Auevechanichkul, N.; Chupanova, M.; Mun, Y.; Ziska, E.; Taylor, M. J.
10.1101/2020.09.03.280917 — immunology — Posted on 2020-09-03
3844 Analysis of diffusion tensor imaging data from UK Biobank confirms dosage effect of 15q11.2 copy-number variation on white matter and shows association with cognition
Silva, A. I.; Kirov, G.; Kendall, K. M.; Bracher-Smith, M.; Wilkinson, L.; Hall, J.; Ulfarsson, M. O.; Walters, G. B.; Stefansson, H.; Stefansson, K.; Linden, D. E. J.; Caseras, X.
10.1101/2020.09.03.280859 — neuroscience — Posted on 2020-09-03
3846 Metabolic changes in brain slices over time: a multiplatform metabolomics approach
Gonzalez-Riano, C.; Tapia-Gonzalez, S.; Perea, G.; Gonzalez-Arias, C.; DeFelipe, J.; Barbas, C.
10.1101/2020.09.03.280966 — neuroscience — Posted on 2020-09-03
3847 Analysis of Metabolic Network Disruption in Engineered Microbial Hosts due to Enzyme Promiscuity
Porokhin,, V.; Amin, S. A.; Nicks, T. B.; Endalur Gopinarayanan, V.; Nair, N. U.; Hassoun, S.
10.1101/2020.09.02.279539 — systems biology — Posted on 2020-09-03
3850 Structural basis for bacterial ribosome quality control
Crowe-McAuliffe, C.; Takada, H.; Murina, V.; Polte, C.; Kasvandik, S.; Tenson, T.; Ignatova, Z.; Atkinson, G. C.; Wilson, D. N.; Hauryliuk, V. N.
10.1101/2020.09.03.281279 — biochemistry — Posted on 2020-09-03
3852 Single generation allele introgression into pure chicken breeds using Sire Dam Surrogate (SDS) mating
Ballantyne, M.; Woodcock, M.; Doddamani, D.; Hu, T.; Taylor, L.; Hawken, R.; McGrew, M.
10.1101/2020.09.03.281204 — genetics — Posted on 2020-09-03
3853 Bioarchaeological analysis of one of the earliest Islamic burials in the Levant
Srigyan, M.; Bolivar, H.; Urena, I.; Sanatana, J.; Petersen, A.; Iriarte, E.; Jakobsson, M.; Smith, C.; Ibanez, J. J.; Götherström, A.; Günther, T.; Valdiosera, C.
10.1101/2020.09.03.281261 — genetics — Posted on 2020-09-03
3855 Unravelling resilience mechanisms in forests: role of non-structural carbohydrates in responding to extreme weather events
D'Andrea, E.; Scartazza, A.; Battistelli, A.; Collalti, A.; Proietti, S.; Rezaie, N.; Matteucci, G.; Moscatello, S.
10.1101/2020.09.03.281105 — ecology — Posted on 2020-09-03
3858 A mesh microelectrode array for non-invasive electrophysiology within neural organoids
McDonald, M.; Sebinger, D.; Brauns, L.; Gonzalez-Cano, L.; Menuchin-Lasowski, Y.; Psathaki, O.-E.; Stumpf, A.; Rauen, T.; Schöler, H.; Jones, P. D.
10.1101/2020.09.02.279125 — neuroscience — Posted on 2020-09-03
3859 White matter integrity requires continuous myelin synthesis at the inner tongue
Meschkat, M.; Steyer, A. M.; Weil, M.-T.; Kusch, K.; Jahn, O.; Piepkorn, L.; Agüi-Gonzalez, P.; Phan, N. T.; Ruhwedel, T.; Sadowski, B.; Rizzoli, S.; Werner, H. B.; Ehrenreich, H.; Nave, K.-A.; Möbius, W.
10.1101/2020.09.02.279612 — neuroscience — Posted on 2020-09-03
3860 Bayesian Connective Field Modeling: a Markov Chain Monte Carlo approach.
Invernizzi, A.; Haak, K. V.; Carvalho, J.; Renken, R.; Cornelissen, F.
10.1101/2020.09.03.281162 — neuroscience — Posted on 2020-09-03
3862 Alternate models of acute dyslipidemia reveal divergent pathways upon atherosclerosis initiation
Hellberg, S.; Shavva, V. s.; Metso, J.; Chen, G.; Li, Q.-Z.; Manfe, V.; Olofsson, P. S.; Jauhiainen, M.; Binder, C. J.; Malin, S. G.
10.1101/2020.09.02.279596 — physiology — Posted on 2020-09-03
3863 Zinc dysregulation in slc30a8 (znt8) mutant zebrafish leads to blindness and disrupts bone mineralisation
Mackay, E. W.; Ibanez Molero, S.; Harjani Tirathdas, L.; Peterson-Maduro, J.; Zang, J.; Neuhauss, S. C.; Schulte-Merker, S.; Wilson, S. W.
10.1101/2020.09.02.279182 — physiology — Posted on 2020-09-03
3864 ETV7 regulates breast cancer stem-like cell plasticity by repressing IFN-response genes
Pezze, L.; Forcato, M.; Pontalti, S.; Badowska, K. A.; Rizzotto, D.; Skvortsova, I.-I.; Bicciato, S.; Ciribilli, Y.
10.1101/2020.09.02.279133 — cancer biology — Posted on 2020-09-03
3866 Comparative analysis of human brain organoids of brainstem and midbrain at single-cell resolution
Kinugawa, K.; Luginbühl, J.; Matsui, T. K.; Eura, N.; Sakaguchi, Y. M.; Shin, J. W.; Sugie, K.; Schwamborn, J. C.; Mori, E.
10.1101/2020.09.02.279380 — bioinformatics — Posted on 2020-09-03
3868 Training a neural network to learn other dimensionality reduction removes data size restrictions in bioinformatics and provides a new route to exploring data representations
Dexter, A.; Thomas, S. A.; Steven, R. T.; Robinson, K. N.; Taylor, A. J.; Elia, E.; Nikula, C.; Campbell, A. D.; Panina, Y.; Najumudeen, A. K.; Murta, T.; Yan, B.; Grabowski, P.; Hamm, G.; Swales, J.; Gilmore, I.; Yuneva, M.; Goodwin, R. J. A.; Barry, S.; Sansom, O. J.; Takats, Z.; Bunch, J.
10.1101/2020.09.03.269555 — bioinformatics — Posted on 2020-09-03
3870 Community-curated and standardised metadata of published ancient metagenomic samples with AncientMetagenomeDir
Fellows Yates, J. A.; Andrades Valtuena, A.; Vagene, A. J.; Cribdon, B.; Velsko, I. M.; Borry, M.; Bravo-Lopez, M. J.; Fernandez-Guerra, A.; Green, E. J.; Ramachandran, S. L.; Heintzman, P. D.; Spyrou, M. A.; Hübner, A.; Gancz, A. S.; Hider, J.; Allshouse, A. F.; Warinner, C. G.
10.1101/2020.09.02.279570 — bioinformatics — Posted on 2020-09-03
3872 Peroxisomes contribute to intracellular calcium dynamics
Sargsyan, Y.; Bickmeyer, U.; Streckfuss-Bomeke, K.; Bogeski, I.; Thoms, S.
10.1101/2020.09.02.279174 — biochemistry — Posted on 2020-09-03
3873 The iron-responsive genome of the chiton Acanthopleura granulata
Varney, R. M.; Speiser, D. I.; McDougall, C.; Degnan, B. M.; Kocot, K. M.
10.1101/2020.05.19.102897 — genomics — Posted on 2020-09-03
3874 A glimpse of antimicrobial resistance gene diversity in kefir and yoghurt
Toth, A. G.; Csabai, I.; Maroti, G.; Jerzsele, A.; Dubecz, A.; Patai, A. V.; Nagy, S. A.; Makrai, L.; Banyai, K.; Szita, G.; Solymosi, N.
10.1101/2020.09.02.279877 — genomics — Posted on 2020-09-03
3876 Analyses of Biomarker Traits in Diverse UK Biobank Participants Identify Associations Missed by European-centric Analysis Strategies
Sun, Q.; Graff, M.; Rowland, B.; Wen, J.; Huang, L.; Lee, M. P.; Avery, C. L.; Franceschini, N.; North, K. E.; Li, Y.; Raffield, L. M.
10.1101/2020.09.02.279844 — genetics — Posted on 2020-09-03
3877 Lions and brown bears colonized North America in multiple synchronous waves of dispersal across the Bering Land Bridge
Salis, A. T.; Bray, S. C. E.; Lee, M. S. Y.; Heiniger, H.; Barnett, R.; Burns, J. A.; Doronichev, V.; Fedje, D.; Golovanova, L.; Harington, C. R.; Hockett, B.; Kosintsev, P.; Lai, X.; Mackie, Q.; Vasiliev, S.; Weinstock, J.; Yamaguchi, N.; Meachen, J.; Cooper, A.; Mitchell, K. J.
10.1101/2020.09.03.279117 — evolutionary biology — Posted on 2020-09-03
3879 Submesoscale dynamics directly shape bacterioplankton community structure in space and time
Fadeev, E.; Wietz, M.; von Appen, W. J.; Noethig, E. M.; Engel, A.; Grosse, J.; Graeve, M.; Boetius, A.
10.1101/2020.09.02.279232 — ecology — Posted on 2020-09-03
3882 Leveraging complex interactions between signaling pathways involved in liver development to robustly improve the maturity and yield of pluripotent stem cell-derived hepatocytes
Raggi, C.; M'Callum, M.-A.; Pham, Q. T.; Gaub, P.; Selleri, S.; Baratang, N.; Mangahas, C. L.; Cagnone, G.; Reversade, B.; Joyal, J.-S.; Paganelli, M.
10.1101/2020.09.02.280172 — developmental biology — Posted on 2020-09-03
3883 SUMOylation- and GAR1-dependent regulation of dyskerin nuclear and subnuclear localization
MacNeil, D. E.; Lambert-Lanteigne, P.; Qin, J.; McManus, F.; Bonneil, E.; Thibault, P.; Autexier, C.
10.1101/2020.09.02.280198 — cell biology — Posted on 2020-09-03
3884 Optimization of negative stage bias potential for faster imaging in large-scale electron microscopy
Lane, R.; Vos, Y.; Wolters, A. H.; van Kessel, L.; Giepmans, B. N. G.; Hoogenboom, J. P.
10.1101/2020.09.03.277830 — cell biology — Posted on 2020-09-03
3885 Identification of a novel cobamide remodeling enzyme in the beneficial human gut bacterium Akkermansia muciniphila
Mok, K. C.; Sokolovskaya, O. M.; Nicolas, A. M.; Hallberg, Z.; Deutschbauer, A. M.; Carlson, H. K.; Taga, M. E.
10.1101/2020.09.02.280537 — microbiology — Posted on 2020-09-03
3886 Massive expansion of human gut bacteriophage diversity
Camarillo-Guerrero, L. F.; Almeida, A.; Rangel-Pineros, G.; Finn, R. D.; Lawley, T. D.
10.1101/2020.09.03.280214 — microbiology — Posted on 2020-09-03
3888 Phenotypic and functional characterisation of first trimester human placental macrophages, Hofbauer cells.
Thomas, J.; Appios, A.; Zhao, X. X.; Dutkiewicz, R. A.; Donde, M. J.; Lee, C.; Naidu, P. M.; Lee, C.; Cerveira, J.; Liu, B.; Ginhoux, F.; Burton, G.; Hamilton, R. S.; Moffett, A.; Sharkey, A.; McGovern, N.
10.1101/2020.09.03.279919 — immunology — Posted on 2020-09-03
3890 Sleep-specific changes in physiological brain pulsations
Helakari, H.; Korhonen, V.; Holst, S. C.; Piispala, J.; Kallio, M.; Vayrynen, T.; Huotari, N.; Raitamaa, L.; Kananen, J.; Jarvela, M.; Raatikainen, V.; Borchardt, V.; Kinnunen, H.; Nedergaard, M.; Kiviniemi, V.
10.1101/2020.09.03.280479 — neuroscience — Posted on 2020-09-03
3892 Dysregulation of hippocampal adult-born immature neurons disrupts a brain-wide network for spatial memory
Bao, H.; Hu, Z.; Lee, S.-h.; Kolagani, R.; Chao, T.-H. H.; Luo, Y.-J.; Ban, W.; Sullivan, H. A.; Gamero-Alameda, S.; Lybrand, Z. R.; Yu, Y.; Hsieh, J.; Wickersham, I. R.; Brenner, S. E.; Shih, Y.-Y. I.; Song, J.
10.1101/2020.09.02.273649 — neuroscience — Posted on 2020-09-03
3894 The sheep brain: an interesting translational model for functional MRI studies?
Just, N.; Adriaensen, H.; Chevillard, P.-M.; Batailler, M.; Dubois, J.-P.; Migaud, M.
10.1101/2020.09.02.280024 — neuroscience — Posted on 2020-09-03
3895 Stimulation of zona incerta selectively modulates pain in humans
Lu, C. W.; Harper, D. E.; Askari, A.; Willsey, M. S.; Vu, P. P.; Schrepf, A. D.; Harte, S. E.; Patil, P. G.
10.1101/2020.09.02.277921 — neuroscience — Posted on 2020-09-03
3899 A centrifuge-based method for identifying novel genetic traits that affect root-substrate adhesion in Arabidopsis thaliana
Eldridge, B. M.; Larson, E. R.; Weldon, L.; Smyth, K. M.; Sellin, A. N.; Chenchiah, I. V.; Liverpool, T. B.; Grierson, C. S.
10.1101/2020.05.14.095448 — plant biology — Posted on 2020-09-03
3903 A DNAmRep epigenetic fingerprint for determining cellular replication age
Minteer, C.; Morselli, M.; Meer, M.; Cao, J.; Lang, S.; Pellegrini, M.; Yan, Q.; Levine, M.
10.1101/2020.09.02.280073 — pathology — Posted on 2020-09-03
3905 Genomic analyses of two Italian oyster mushroom Pleurotus pulmonarius strains
Vidal-Diez de Ulzurrun, G.; Lee, Y.-Y.; Stajich, J. E.; Schwarz, E. M.; Hsueh, Y.-P.
10.1101/2020.09.03.281089 — genomics — Posted on 2020-09-03
3908 Environment and sex control lifespan and telomere length in wild-derived African killifish
Reichard, M.; Giannetti, K.; Ferreira, T.; Vrtilek, M.; Polacik, M.; Blazek, R.; Ferreira, M. G.
10.1101/2020.09.03.280792 — evolutionary biology — Posted on 2020-09-03
3912 Virome-wide serological profiling reveals association of herpesviruses with obesity
Hasan, M. R.; Rahman, M.; Khan, T.; Saeed, A.; Sundararaju, S.; Flores, A.; Hawken, P.; Rawat, A.; Elkum, N.; Hussain, K.; Tan, R.; Tang, P.; Marr, N.
10.1101/2020.09.02.280503 — microbiology — Posted on 2020-09-03
3914 Gaze Behaviour Reveals Flexible Encoding of Competing Reach Goals Under Conditions of Target Uncertainty
de Brouwer, A. J.; Carter, M. J.; Smail, L. C.; Wolpert, D. M.; Gallivan, J. P.; Flanagan, J. R.
10.1101/2020.09.02.279414 — neuroscience — Posted on 2020-09-03
3916 Microglia-neuron communication at nodes of Ranvier depends on neuronal activity through potassium release and contributes to myelin repair.
Ronzano, R.; Roux, T.; Thetiot, M.; Aigrot, M.-S.; Richard, L.; Lejeune, F.-X.; Mazuir, E.; Vallat, J.-M.; Lubetzki, C.; Desmazieres, A.
10.1101/2020.09.02.279562 — neuroscience — Posted on 2020-09-03
3917 Longitudinal cerebrospinal fluid proteome profiling of acute and sustained antidepressant-like effects of (2R,6R)-hydroxynorketamine (HNK) reveals involvement of glucocorticoid receptor signaling
Herzog, D. P.; Perumal, N.; Manicam, C.; Treccani, G.; Nadig, J.; Rossmanith, M.; Engelmann, J.; Jene, T.; Hasch, A.; van der Kooij, M. A.; Lieb, K.; Gassen, N. C.; Grus, F. H.; Mueller, M. B.
10.1101/2020.09.03.280834 — neuroscience — Posted on 2020-09-03
3921 Prognostic significance of Substance P/ Neurokinin 1 receptor and its association with hormonal receptors in breast carcinoma
mehboob, r.; Gilani, S. A.; Hassan, a.; Tanvir, I.; Khan, R.; Javaid, S.; Akram, J.; Ahmad, F.; Munoz, M.; sadaf,
10.1101/2020.06.27.175083 — pathology — Posted on 2020-09-03
3926 Whole-brain functional connectivity neuromarkers uncover the cognitive recovery scheme for overt hepatic encephalopathy after liver transplantation
Cheng, Y.; Shen, W.; Xu, J.; Amey, R.; Huang, L.; Zhang, X.; Li, J.; Akhavan, C.; Duffy, B.; Jiang, W.; Liu, M.; Kim, H.
10.1101/2020.09.01.278614 — neuroscience — Posted on 2020-09-03
3928 BrainPhys neuronal medium optimized for imaging and optogenetics in vitro
Zabolocki, M.; McCormack, K.; van den Hurk, M.; Milky, B.; Shoubridge, A.; Adams, R.; Tran, J.; Mahadevan-Jansen, A.; Reineck, P.; Thomas, J.; Hutchinson, M. R.; Mark, C.; Anonuevo, A.; Chew, L. H.; Hirst, A. J.; Lee, V. M.; Knock, E.; Bardy, C.
10.1101/2020.09.02.276535 — neuroscience — Posted on 2020-09-03
3931 A connectome-based prediction model of long-term memory
Lin, Q.; Yoo, K.; Shen, X.; Constable, R. T.; Chun, M. M.
10.1101/2020.09.02.279372 — neuroscience — Posted on 2020-09-03
3932 Translational profiling of mouse dopaminoceptive neurons reveals a role of PGE2 in dorsal striatum
Montalban, E.; Giralt, A.; Taing, L.; Nakamura, Y.; Martin, C.; de Pins, B.; Pelosi, A.; Goutebroze, L.; Castell, L.; Wang, W.; Daila Neiburga, K.; Vestito, L.; Nairn, A. C.; Valjent, E.; Herve, D.; Heintz, N.; Gambardella Le Novere, N.; Greengard, P.; Roussarie, J.-P.; Girault, J.-A.
10.1101/2020.09.02.279240 — neuroscience — Posted on 2020-09-03
3934 Myristate can be used as a carbon and energy source for the asymbiotic growth of arbuscular mycorrhizal fungi
Sugiura, Y.; Akiyama, R.; Tanaka, S.; Yano, K.; Kameoka, H.; Marui, S.; Saito, M.; Kawaguchi, M.; Akiyama, K.; Saito, K.
10.1101/731489 — microbiology — Posted on 2020-09-03
3935 Theta-phase dependent neuronal coding during sequence learning in human single neurons.
Reddy, L.; Self, M. W.; Zoefel, B.; Poncet, M.; Possel, J. K.; Peters, J. C.; Baayen, J. C.; Idema, S.; VanRullen, R.; Roelfsema, P. R.
10.1101/630095 — neuroscience — Posted on 2020-09-03
3939 Deploying a novel tuberculosis molecular bacterial load assay to assess the elimination rate of Mycobacterium tuberculosis in patients with multidrug-resistant tuberculosis in Tanzania
Mbelele, P. M.; Mpolya, E. A.; Sauli, E.; Mtafya, B.; Ntinginya, N. E.; Addo, K. K.; Kreppel, K.; Mfinanga, S.; Phillips, P. P. J.; Gillespie, S. H.; Heysell, S. K.; Sabiiti, W.; Mpagama, S.
10.1101/2020.09.02.280511 — microbiology — Posted on 2020-09-03
3940 Elucidating Human Milk Oligosaccharide biosynthetic genes through network-based multi-omics integration
Kellman, B. P.; Richelle, A.; Yang, J.-Y. E.; Chapla, D. G.; Chiang, A. W.-T.; Najera, J.; Bao, B.; Koga, N.; Mohammad, M. A.; Bruntse, A. B.; Haymond, M. W.; Bode, L.; Lewis, N. E.
10.1101/2020.09.02.278663 — systems biology — Posted on 2020-09-03
3943 Synthetic mammalian signaling circuits for robust cell population control
Ma, Y.; Budde, M. W.; Mayalu, M. N.; Zhu, J.; Murray, R. M.; Elowitz, M. B.
10.1101/2020.09.02.278564 — synthetic biology — Posted on 2020-09-03
3945 A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth
Gillis, J. L.; Hinneh, J. A.; Ryan, N. K.; Irani, S.; Moldovan, M.; Shrestha, R. K.; Quek, L.-E.; Hoy, A. J.; Holst, J.; Centenera, M. M.; Mills, I. G.; Lynn, D. J.; Selth, L. A.; Butler, L. M.
10.1101/2020.09.02.279356 — cancer biology — Posted on 2020-09-03
3946 Antibody Upstream Sequences Diversity and Its Biological Implications Revealed by Repertoire Sequencing
Zhu, Y.; Yang, X.; Wu, J.; Tang, H.; Wang, Q.; Guan, J.; Xie, W.; Chen, S.; Chen, Y.; Wang, M.; Lan, C.; Wei, L.; Sun, C.; Zhang, Z.
10.1101/2020.09.02.280396 — bioinformatics — Posted on 2020-09-03
3947 Fine-scale population structure and demographic history of British Pakistanis
Arciero, E.; Mezzavilla, M.; Dogra, S.; Tsismentzoglou, T.; Huang, Q. Q.; Hunt, K. A.; Mason, D.; van Heel, D. A.; Sheridan, E.; Wright, J.; Small, N.; Carmi, S.; Iles, M. M.; Martin, H. C.
10.1101/2020.09.02.279190 — genomics — Posted on 2020-09-03
3950 Genome-wide maps of enhancer regulation connect risk variants to disease genes
Nasser, J.; Bergman, D. T.; Fulco, C. P.; Guckelberger, P.; Doughty, B. R.; Patwardhan, T. A.; Jones, T. R.; Nguyen, T. H.; Ulirsch, J. C.; Natri, H. M.; Weeks, E. M.; Munson, G.; Kane, M.; Kang, H. Y.; Cui, A.; Ray, J. P.; Eisenhaure, T. M.; Mualim, K.; Collins, R. L.; Dey, K.; Price, A. L.; Epstein, C. B.; Kundaje, A.; Xavier, R. J.; Daly, M. J.; Huang, H.; Finucane, H. K.; Hacohen, N.; Lander, E. S.; Engreitz, J. M.
10.1101/2020.09.01.278093 — genetics — Posted on 2020-09-03
3953 Identification and evolution of Cas9 tracrRNAs
Dooley, S. K.; Baken, E. K.; Moss, W.; Howe, A.; Young, J. K.
10.1101/2020.09.02.279885 — evolutionary biology — Posted on 2020-09-03
3955 Potential universal PCR method to detect decapod hepanhamaparvovirus (DHPV) in crustaceans
Srisala, J.; Thaiue, D.; Sanguanrut, P.; Aldama-Cano, D. J.; Flegel, T. W.; Sritunyalucksana, K.
10.1101/2020.09.01.278721 — molecular biology — Posted on 2020-09-03
3956 Calorie Restriction Prevents Age-Related Changes in the Intestinal Microbiota
Kurup, K.; Matyi, S.; Giles, C. B.; Wren, J. D.; Jones, K.; Ericsson, A.; Raftery, D.; Wang, L.; Promislow, D.; Richardson, A.; Unnikrishnan, A.
10.1101/2020.09.02.279778 — molecular biology — Posted on 2020-09-03
3959 miR-200 deficiency promotes lung cancer metastasis by activating cancer-associated fibroblasts
Xue, B.; Chuang, C.-H.; Prosser, H. M.; Fuziwara, C. S.; Chan, C.; Sahasrabudhe, N.; Kühn, M.; Wu, Y.; Chen, J.; Biton, A.; Chen, C.; Wilkinson, J. E.; McManus, M. T.; Bradley, A.; Winslow, M. M.; Su, B.; He, L.
10.1101/2020.09.02.276550 — cancer biology — Posted on 2020-09-03
3961 comboFM: leveraging multi-way interactions for systematic prediction of drug combination effects
Julkunen, H. J.; Cichonska, A.; Gautam, P.; Szedmak, S.; Douat, J.; Pahikkala, T.; Aittokallio, T.; Rousu, J.
10.1101/2020.09.02.278986 — bioinformatics — Posted on 2020-09-03
3962 Graphia: A platform for the graph-based visualisation and analysis of complex data
Freeman, T.; Horsewell, S.; Patir, A.; Harling-Lee, J.; Regan, T.; Shih, B. B.; Prendergast, J.; Hume, D. A.; Angus, T.
10.1101/2020.09.02.279349 — bioinformatics — Posted on 2020-09-03
3964 Triplet-Triplet Annihilation PLGA-Nanoparticles for Cancer Bioimaging
Vepris, O.; Eich, C.; Feng, Y.; Zhang, H.; Kaijzel, E. L.; Cruz, L. J.
10.1101/2020.09.02.274969 — bioengineering — Posted on 2020-09-03
3966 Amyloid particles facilitate surface-catalyzed cross-seeding by acting as promiscuous nanoparticles
Koloteva-Levine, N.; Marchante, R.; Purton, T. J.; Hiscock, J. R.; Tuite, M. F.; Xue, W.-F.
10.1101/2020.09.01.278481 — biochemistry — Posted on 2020-09-03
3967 The Epidermal Barrier is Indispensable for Systemic Energy Homeostasis
Neess, D.; Kruse, V.; Marcher, A.-B.; Waede, M. R.; Vistisen, J.; Moeller, P. M.; Petersen, R.; Brewer, J. R.; Ma, T.; Colleluori, G.; Severi, I.; Cinti, S.; Gerhart-Hines, Z.; Mandrup, S.; Faergeman, N. J.
10.1101/2020.09.01.277723 — biochemistry — Posted on 2020-09-03
3969 Phenotypic and transcriptomic responses to stress differ according to population geography in an invasive species
Pierre, M.; Jaquet, A.; Picarle, J.; Fablet, M.; Merel, V.; Delignette-Muller, M.-L.; Galvao Ferrarini, M.; Gibert, P.; Vieira, C.
10.1101/2020.09.02.279315 — genomics — Posted on 2020-09-03
3972 Deleterious impacts of inactivity and beneficial impacts of neuromuscular electrical stimulation on muscle structure and function in the zebrafish model of Duchenne Muscular Dystrophy
Kilroy, E. A.; Brann, K. L.; Schaffer, C. E.; Varney, D.; Silknitter, K. J.; Miner, J. N.; Almaghasilah, A.; Spellen, T. L.; Lewis, A. D.; Tilbury, K.; King, B. L.; Kelley, J. B.; Henry, C.
10.1101/2020.09.02.279513 — developmental biology — Posted on 2020-09-03
3973 Exostosin-1 Glycosyltransferase Regulates Endoplasmic Reticulum Architecture and Dynamics
Kerselidou, D.; Dohai, B. S.; Nelson, D. R.; Daakour, S.; De Cock, N.; Kim, D.-K.; Olivet, J.; El Assal, D. C.; Jaiswal, A.; Saha, D.; Pain, C.; Matthijssens, F.; Lemaitre, P.; Herfs, M.; Chapuis, J.; Ghesquiere, B.; Vertommen, D.; Kriechbaumer, V.; Knoops, K.; Lopez-Iglesias, C.; van Zandvoort, M.; Lambert, J.-C.; Hanson, J.; Desmet, C.; Thiry, M.; Lauersen, K.; Vidal, M.; Van Vlierberghe, P.; Dequiedt, F.; Salehi-Ashtiani, K.; Twizere, J.-C.
10.1101/2020.09.02.275925 — cell biology — Posted on 2020-09-03
3975 Title: Reliability, sensitivity and predictive value of fMRI during multiple object tracking as a marker of cognitive training gain in combination with tDCS in stroke survivors
Kolskaar, K. K.; Richard, G.; Alnaes, D.; Dorum, E. S.; Sanders, A.-M.; Ulrichsen, K. M.; Monereo Sanchez, J.; Ihle-Hansen, H.; Nordvik, J. E.; Westlye, L. T.
10.1101/603985 — neuroscience — Posted on 2020-09-02
3977 Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations
Rees, E.; Creeth, H.; Hwu, H.-G.; Chen, W. J.; Tsuang, M.; Glatt, S.; Rey, R.; Kirov, G.; Walters, J.; Holmans, P.; Owen, M.; O'Donovan, M.
10.1101/2020.09.02.279265 — genetics — Posted on 2020-09-02
3978 Vertical transmission at the pathogen-symbiont interface: Serratia symbiotica and aphids
Perreau, J.; Patel, D. J.; Anderson, H.; Maeda, G. P.; Elston, K. M.; Barrick, J. E.; Moran, N. A.
10.1101/2020.09.01.279018 — microbiology — Posted on 2020-09-02
3980 Kcns3 Deficiency Disrupts Parvalbumin Neuron Physiology in Mouse Prefrontal Cortex: Implications for the pathophysiology of schizophrenia
Miyamae, T.; Hashimoto, T.; Abraham, M.; Kawabata, R.; Koshikizawa, S.; Bian, Y.; Kikuchi, M.; Ermentrout, G. B.; Lewis, D. A.; Gonzalez-Burgos, G.
10.1101/2020.09.02.280107 — neuroscience — Posted on 2020-09-02
3986 Myosin 1b Flattens and Prunes Branched Actin Filaments.
Pernier, J.; Morchain, A.; Caorsi, V.; Bertin, A.; Bousquet, H.; Bassereau, P.; Coudrier, E.
10.1101/2020.02.26.966663 — biophysics — Posted on 2020-09-02
3987 A systematic dissection of human primary osteoblasts in vivo at single-cell resolution
Gong, Y.; Yang, J.; Li, X.; Zhou, C.; Chen, Y.; wang, z.; Qiu, X.; Liu, Y.; Zhang, H.; Greenbaum, J.; Chen, L.; Hu, Y.; Xie, J.; Yang, X.; Li, Y.; Bai, Y.; Wang, Y.-P.; Chen, Y.; Tan, L.-J.; Shen, H.; Xiao, H.; deng, H.-W.
10.1101/2020.05.12.091975 — bioinformatics — Posted on 2020-09-02
3994 C1 compounds shape the microbial community of an abandoned century-old oil exploration well.
Rojas-Gätjens, D.; Fuentes-Schweizer, P.; Rojas-Jimenez, K.; Perez-Pantoja, D.; Avendano, R.; Alpizar, R.; Coronado-Ruiz, C.; Chavarria, M.
10.1101/2020.09.01.278820 — microbiology — Posted on 2020-09-02
3997 BATF3-dependent induction of IL-27 by B cells bridges the innate and adaptive stages of the antibody response
Yan, H.; Wang, R.; Wang, J.; Wu, S.; Fernandez, M.; Rivera, C. E.; Cervantes, C.; Moroney, J. B.; Li, X.; Zhang, N.; Zan, H.; Meng, X.; Zhang, F.; Zheng, S.; Chen, Y.; Yin, Z.; Kedl, R.; Min, B.; Hunter, C. A.; Xiang, Y.; Casali, P.; Xu, Z.
10.1101/2020.06.26.117010 — immunology — Posted on 2020-09-02
3998 Laser Ablation of the Pia Mater for Insertion of High-Density Microelectrode Arrays in a Translational Sheep Model
Boergens, K. M.; Tadic, A.; Hopper, M. S.; McNamara, I.; Sahasrabuddhe, K.; Kong, Y.; Straka, M.; Sohal, H. H. S.; Angle, M. R.
10.1101/2020.08.27.269233 — neuroscience — Posted on 2020-09-02
3999 The language network is recruited but not required for non-verbal event semantics
Ivanova, A. A.; Mineroff, Z.; Zimmerer, V.; Kanwisher, N.; Varley, R.; Fedorenko, E.
10.1101/696484 — neuroscience — Posted on 2020-09-02
4000 Divergent use of metabolic fluxes in breast cancer metastasis
Mathur, D.; Liao, C.; La Ferlita, A.; Alaimo, S.; Ferro, A.; Xavier, J.
10.1101/2020.08.03.234468 — cancer biology — Posted on 2020-09-02
4001 Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients
Miller-Vedam, L. E.; Bräuning, B.; Popova, K. D.; Schirle Oakdale, N. T.; Bonnar, J. L.; Prabu, J. R.; Boydston, E. A.; Sevillano, N.; Shurtleff, M. J.; Craik, C. S.; Schulman, B.; Frost, A.; Weissman, J. S.
10.1101/2020.09.02.280008 — biophysics — Posted on 2020-09-02
4007 Manipulation of IRE1-dependent MAPK signaling by a Vibrio agonist-antagonist effector pair
De Nisco, N. J.; Casey, A. K.; Kanchwala, M.; Lafrance, A. E.; Coskun, F. S.; Kinch, L. N.; Grishin, N. V.; Xing, C.; Orth, K.
10.1101/2020.09.01.278937 — microbiology — Posted on 2020-09-02
4009 Development of a copper-graphene nanocomposite based transparent coating with antiviral activity against influenza virus
Jana, I. D.; Kumbhakar, P.; Banerjee, S.; Gowda, C. C.; Kedia, N.; Kuila, S. K.; Banerjee, S.; Das, N. C.; Das, A. K.; Manna, I.; Tiwary, C. S.; Mondal, A.
10.1101/2020.09.02.279737 — microbiology — Posted on 2020-09-02
4010 Vertical transmission at the pathogen-symbiont interface: Serratia symbiotica and aphids
Perreau, J.; Patel, D. J.; Anderson, H.; Maeda, G. P.; Elston, K. M.; Barrick, J. E.; Moran, N. A.
10.1101/2020.09.01.279018 — microbiology — Posted on 2020-09-02
4011 Recombinant Paraprobiotics as a New Paradigm for Treating Gastrointestinal Nematode Parasites of Humans
Li, H.; Abraham, A.; Gazzola, D.; Hu, Y.; Beamer, G.; Flanagan, K.; Soto, E.; Rus, F.; Mirza, Z.; Draper, A.; Vakalapudi, S.; Stockman, C.; Bain, P.; Urban, J. F.; Ostroff, G. R.; Aroian, R. V.
10.1101/2020.09.02.278341 — microbiology — Posted on 2020-09-02
4014 Distinct clonal evolution of B-cells in HIV controllers with neutralizing antibody breadth
Cizmeci, D.; Lofano, G.; Dugast, A.-S.; Kim, D.; Cavet, G.; Nguyen, N.; Tan, Y. C.; Seaman, M. S.; Alter, G.; Julg, B.
10.1101/2020.09.02.277566 — immunology — Posted on 2020-09-02
4015 Induction of a regulatory myeloid program in bacterial sepsis and severe COVID-19
Reyes, M.; Filbin, M. R.; Bhattacharyya, R. P.; Sonny, A.; Mehta, A.; Billman, K.; Kays, K. R.; Pinilla-Vera, M.; Benson, M. E.; MGH COVID-19 Collection & Processing Team, ; Cosimi, L. A.; Hung, D. T.; Levy, B. D.; Villani, A.-C.; Sade-Feldman, M.; Baron, R. M.; Goldberg, M. B.; Blainey, P. C.; Hacohen, N.
10.1101/2020.09.02.280180 — immunology — Posted on 2020-09-02
4019 GenomeChronicler: The Personal Genome Project UK Genomic Report Generator Pipeline
Guerra-Assuncao, J. A.; Conde, L.; Moghul, I.; Webster, A. P.; Ecker, S.; Chervova, O.; Chatzipantsiou, C.; Prieto, P. P.; Beck, S.; Herrero, J.
10.1101/2020.01.06.873026 — bioinformatics — Posted on 2020-09-02
4022 Genomic diversity of Escherichia coli isolates from healthy children in rural Gambia
Foster-Nyarko, E.; Alikhan, N.-F.; Ikumapayi, U. N.; Golam, S.; Hossain, M. J.; Okoi, C.; Tientcheu, P.-E.; Defernez, M.; OGrady, J.; Antonio, M.; Pallen, M. J.
10.1101/2020.08.28.271627 — ecology — Posted on 2020-09-02
4023 Longitudinal tracking reveals sustained polyclonal repopulation of human-HSPC in humanized mice despite vector integration bias
Suryawanshi, G. W.; Arokium, H.; Kim, S.; Khamaikawin, W.; Lin, S.; Shimizu, S.; Chupradit, K.; Lee, Y.; Xie, Y.; Guan, X.; Suryawanshi, V.; Presson, A. P.; An, D.-S.; Chen, I. S. Y.
10.1101/2020.08.21.261537 — molecular biology — Posted on 2020-09-02
4024 A stress-induced Tyrosine tRNA depletion response mediates codon-based translational repression and growth suppression
Huh, D.; Passarelli, M. C.; Gao, J.; Dusmatova, S. N.; Goin, C.; Fish, L.; Pinzaru, A. M.; Molina, H.; McMillan, E. A.; Asgharian, H.; Goodarzi, H.; Tavazoie, S. F.
10.1101/416727 — molecular biology — Posted on 2020-09-02
4025 Exploiting oxalotrophic bacteria to control Aspergillus niger lung infections
Palmieri, F.; Palmieri, I.; Noormamode, N.; Estoppey, A.; Ishak, M. O.; Kelliher, J. M.; Vallat, A.; Iyer, R.; Bindschedler, S.; Davenport, K.; Chain, P. S. G.; Harris, J. F.; Junier, P.
10.1101/2020.08.20.259929 — microbiology — Posted on 2020-09-02
4026 Isolation of potential plant growth-promoting bacteria from nodules of legumes grown in arid Botswana soil
Kosty, M. A.; Pule-Meulenberg, F.; Humm, E. A.; Martinez-Hidalgo, P.; Maymon, M.; Mohammadi, S.; Cary, J.; Yang, P.; Reddi, K.; Huntemann, M.; Clum, A.; Foster, B.; Foster, B.; Roux, S.; Palaniappan, K.; Vargheses, N.; Mukherjee, S.; Reddy, T. B. K.; Daum, C.; Copeland, A.; Ivanova, N. N.; Kyrpides, N. C.; Glavina del Rio, T.; Eloe-Fadrosh, E. A.; Hirsch, A. M.
10.1101/2020.09.02.257907 — microbiology — Posted on 2020-09-02
4028 BiPOLES: a tool for bidirectional dual-color optogenetic control of neurons
Vierock, J.; Rodriguez-Rozada, S.; Pieper, F.; Dieter, A.; Bergs, A.; Zeitzschel, N.; Ahlbeck, J.; Sauter, K.; Gottschalk, A.; Engel, A. K.; Hegemann, P.; Wiegert, J. S.
10.1101/2020.07.15.204347 — neuroscience — Posted on 2020-09-02
4029 Neurotransmitter Classification from Electron Microscopy Images at Synaptic Sites in Drosophila
Eckstein, N.; Bates, A. S.; Du, M.; Hartenstein, V.; Jefferis, G. S. X. E.; Funke, J.
10.1101/2020.06.12.148775 — neuroscience — Posted on 2020-09-02
4030 Synthetic Cellular Immunity based on CAR repertoire for Human Immunotherapy
Fu, W.; Ma, Z.; Wang, C.; Li, T.; Lin, F.; Mao, R.; Lei, C.; Zhao, J.; Hu, S.
10.1101/868653 — bioengineering — Posted on 2020-09-02
4031 Sulfur reduction coupled with anaerobic ammonium oxidation drove prebiotic proto-anabolic networks
Bao, P.; Li, G.-X.; Zhao, J.-Y.; Wu, K.; Wang, J.; Jia, X.-Y.; Zhang, H.-E.; He, Y.-Q.; Li, H.; Xiao, K.-Q.
10.1101/461707 — biochemistry — Posted on 2020-09-02
4036 Long-read sequencing resolves structural variants in SERPINC1 causing antithrombin deficiency and identifies a complex rearrangement and a retrotransposon insertion not characterized by routine diagnostic methods
de la Morena-Barrio, B.; Stephens, J.; de la Morena-Barrio, M. E.; Stefanucci, L.; Padilla, J.; Miñano, A.; Gleadall, N.; Luis García, J.; López-Fernández, M. F.; Morange, P.-E.; Puurunen, M. K.; Undas, A.; Vidal, F.; NIHR BioResource, ; Raymond, F. L.; Vicente García, V.; Ouwehand, W. H.; Corral, J.; Sanchis-Juan, A.
10.1101/2020.08.28.271932 — genomics — Posted on 2020-09-02
4037 Reverse regression increases power for detecting trans-eQTLs
Banerjee, S.; Simonetti, F. L.; Detrois, K. E.; Kaphle, A.; Mitra, R.; Nagial, R.; Soeding, J.
10.1101/2020.05.07.083386 — genetics — Posted on 2020-09-02
4038 Thyroid hormone regulates proximodistal identity in the fin skeleton
Hu, Y.; Harper, M. A.; Acosta, B.; Donahue, J.; Bui, H.; Lee, H.; Nguyen, S.; McMenamin, S.
10.1101/2020.08.18.256354 — developmental biology — Posted on 2020-09-02
4040 Natural Killer cell activation, reduced ACE2, TMPRSS2, cytokines G-CSF, M-CSF and SARS-CoV-2-S pseudovirus infectivity by MEK inhibitor treatment of human cells
Zhou, L.; Huntington, K.; Zhang, S.; Carlsen, L.; So, E.-Y.; Parker, C.; Sahin, I.; Safran, H.; Kamle, S.; Lee, C.-M.; Lee, C.-G.; Elias, J. A.; Campbell, K. S.; Naik, M. T.; Atwood, W. J.; Youssef, E.; Pachter, J. A.; Navaraj, A.; Seyhan, A. A.; Liang, O.; El-Deiry, W.
10.1101/2020.08.02.230839 — cell biology — Posted on 2020-09-02
4045 Unique mutational changes in SARS-CoV-2 genome: A case study for the largest state of India
Prasad, P.; Prakash, S.; Sahu, K.; Singh, B.; Shukla, S.; Mishra, H.; Khan, D. N.; Prakash, O.; Bhatt, M.; Barik, S.; Asif, M. H.; Sawant, S. V.; Jain, A.; Bag, S. K.
10.1101/2020.08.24.265827 — bioinformatics — Posted on 2020-09-02
4046 Feature-based encoding of face identity by single neurons in the human medial temporal lobe
Cao, R.; Wang, J.; Lin, C.; Rutishauser, U.; Todorov, A.; Li, X.; Brandmeir, N.; Wang, S.
10.1101/2020.09.01.278283 — neuroscience — Posted on 2020-09-02
4047 Lotus japonicus karrikin receptors display divergent ligand-binding specificities and organ-dependent redundancy
Carbonnel, S.; Torabi, S.; Griesmann, M.; Bleek, E.; Tang, Y.; Buchka, S.; Basso, V.; Shindo, M.; Boyer, F.-D.; Wang, T. L.; Udvardi, M.; Waters, M.; Gutjahr, C.
10.1101/754937 — plant biology — Posted on 2020-09-02
4048 PhenoImage: an open-source GUI for plant image analysis
Zhu, F.; Saluja, M.; Singh, J.; Paul, P.; Sattler, S. E.; Staswick, P.; Walia, H.; Yu, H.
10.1101/2020.09.01.278234 — plant biology — Posted on 2020-09-02
4049 Impact of Screening and Follow-up Colonoscopy Adenoma Sensitivity on Colorectal Cancer Screening Outcomes in the CRC-AIM Microsimulation Model
Fisher, D. A.; Saoud, L.; Hassmiller Lich, K.; Fendrick, A. M.; Ozbay, A. B.; Borah, B. J.; Matney, M.; Parton, M.; Limburg, P.
10.1101/2020.08.31.271924 — cancer biology — Posted on 2020-09-02
4055 LXR alters CD4+ T cell function through direct regulation of glycosphingolipid synthesis
Waddington, K. E.; Robinson, G. A.; Rubio Cuesta, B.; Chrifi-Alaoui, E.; Andreone, S.; Poon, K. S.; Ivanova, I.; Martin-Gutierrez, L.; Owen, D.; Jury, E. E.; Pineda-Torra, I.
10.1101/721050 — immunology — Posted on 2020-09-02
4056 Fully Automated Detection of Paramagnetic Rims in Multiple Sclerosis Lesions on 3T Susceptibility-Based MR Imaging
Lou, C.; Sati, P.; Absinta, M.; Clark, K.; Dworkin, J. D.; Valcarcel, A. M.; Schindler, M. K.; Reich, D. S.; Sweeney, E. M.; Shinohara, R. T.
10.1101/2020.08.31.276238 — neuroscience — Posted on 2020-09-02
4059 Drifting Assemblies for Persistent Memory
Kalle Kossio, F. Y.; Goedeke, S.; Klos, C.; Memmesheimer, R.-M.
10.1101/2020.08.31.276147 — neuroscience — Posted on 2020-09-02
4063 Mechanical Loading Recovers Bone but not Muscle Lost During Unloading
Krause, A. R.; Speacht, T. A.; Steiner, J. L.; Lang, C. H.; Donahue, H.
10.1101/2020.09.01.275990 — physiology — Posted on 2020-09-02
4065 Modeling SARS-CoV-2 infection in vitro with a human intestine-on-chip device
Guo, Y.; Luo, R.; Wang, Y.; Deng, P.; Zhang, M.; Wang, P.; Zhang, X.; Cui, K.; Tao, T.; Li, Z.; Chen, W.; Zheng, Y.; Qin, J.
10.1101/2020.09.01.277780 — bioengineering — Posted on 2020-09-02
4068 Structural Variants in SARS-CoV-2 Occur at Template-Switching Hotspots
Chrisman, B.; Paskov, K.; Stockham, N.; Tabatabaei, K.; Jung, J.-Y.; Washington, P.; Varma, M.; Woo Sun, M.; Maleki, S.; Wall, D. P.
10.1101/2020.09.01.278952 — genetics — Posted on 2020-09-02
4069 GWAS of Over 427,000 Individuals Establishes GABAergic and Synaptic Molecular Pathways as Key for Cognitive Executive Functions
Hatoum, A. S.; Morrison, C. L.; Mitchell, E. C.; Lam, M.; Reineberg, A. E.; Palmer, R. H. C.; Benca-Bachmann, C. E.; Evans, L. M.; Keller, M. C.; Friedman, N. P.
10.1101/674515 — genetics — Posted on 2020-09-02
4072 Spike mutation D614G alters SARS-CoV-2 fitness and neutralization susceptibility
Plante, J. A.; Liu, Y.; Liu, J.; Xia, H.; Johnson, B. A.; Lokugamage, K. G.; Zhang, X.; Muruato, A. E.; Zou, J.; Fontes-Garfias, C. R.; Mirchandani, D.; Scharton, D.; Bilello, J. P.; Ku, Z.; An, Z.; Kalveram, B.; Freiberg, A. N.; Menachery, V. D.; Xie, X.; Plante, K. S.; Weaver, S. C.; Shi, P.-Y.
10.1101/2020.09.01.278689 — microbiology — Posted on 2020-09-02
4073 Prime-boost protein subunit vaccines against SARS-CoV-2 are highly immunogenic in mice and macaques
Tan, H.-X.; Juno, J. A.; Lee, W. S.; Barber-Axthelm, I.; Kelly, H. G.; Wragg, K. M.; Esterbauer, R.; Amarasena, T.; Mordant, F. L.; Subbarao, K.; Kent, S. J.; Wheatley, A. K.
10.1101/2020.09.01.278630 — immunology — Posted on 2020-09-02
4074 Selective axonal translation of prenylated Cdc42 mRNA isoform supports axon growth
Lee, S. J.; Kar, A. N.; Zdradzinski, M. Z.; Patel, P.; Sahoo, P. K.; Kawaguchi, R.; Aguilar, B. J.; Lanz, K. D.; McCain, C. R.; Coppola, G.; Lu, Q.; Twiss, J. L.
10.1101/366369 — neuroscience — Posted on 2020-09-02
4076 Principles of organelle membranebridging established using cytosolictether mimics
Kamal, M. A.; Janes, J. A.; Li, L.; Thibaudau, F.; Smith, A.-S.; Sengupta, K.
10.1101/2020.09.02.279398 — biophysics — Posted on 2020-09-02
4083 Parallel Movement-suppressing Striatal Output Pathways
Cui, Q.; Du, X.; Chang, I.; Pamukcu, A.; Lilascharoen, V.; Berceau, B.; Garcia, D.; Hong, D.; Chon, U.; Narayanan, A.; Kim, Y.; Lim, B.; Chan, S.
10.1101/2020.09.02.273615 — neuroscience — Posted on 2020-09-02
4085 A balance between matrix deformation and the coordination of turning events governs directed neutrophil migration in 3-D matrices
Francois, J.; Kandasamy, A.; Yeh, Y.-T.; Ayala, C.; Meili, R.; Chien, S.; Lasheras, J. C.; del Alamo, J. C.
10.1101/2020.09.02.868505 — biophysics — Posted on 2020-09-02
4086 Intracellular stiffening competes with cortical softening in glioblastoma cells
Alibert, C.; Pereira, D.; Lardier, N.; Etienne-Manneville, S.; Goud, B.; Asnacios, A.; Manneville, J.-B.
10.1101/2020.09.02.279794 — biophysics — Posted on 2020-09-02
4089 Visualizing the metazoan proliferation-terminal differentiation decision in vivo
Kohrman, A. Q.; Adikes, R. C.; Martinez, M. A. Q.; Palmisano, N. J.; Smith, J. J.; Medwig-Kinney, T. N.; Min, M.; Sallee, M. D.; Ahmed, O. B.; Kim, N.; Liu, S.; Morabito, R.; Weeks, N.; Zhao, Q.; Zhang, W.; Feldman, J.; Barkoulas, M.; Pani, A. M.; Spencer, S. L.; Martin, B. L.; Matus, D. Q.
10.1101/2019.12.18.881888 — developmental biology — Posted on 2020-09-02
4090 ASO-based PKM Splice-switching Therapy Inhibits Hepatocellular Carcinoma Cell Growth
Ma, W. K.; Scharner, J.; Costa, A. S. H.; Jeong, H. Y.; Jackson, M.; Rigo, F.; Bennett, F. C.; Krainer, A.
10.1101/2020.09.01.278580 — cancer biology — Posted on 2020-09-02
4091 Accurate transcription start sites enable mining for the cis-regulatory determinants of tissue specific gene expression
Ansariola, M.; Fraser, V. N.; Filichkin, S. A.; Ivanchenko, M. G.; Bright, Z. A.; Gould, R. A.; Ozguc, O. R.; O'Neil, S. T.; Megraw, M.
10.1101/2020.09.01.278424 — genomics — Posted on 2020-09-02
4093 Functional insights from KpfR, a new transcriptional regulator of fimbrial expression that is crucial for Klebsiella pneumoniae pathogenicity
Gomes, A. E. I.; Pacheco, T.; dos Santos, C. d. S.; Pereira, J. A.; Ribeiro, M. L.; Darrieux, M.; Caldas Ferraz, L. F.
10.1101/2020.08.31.276717 — microbiology — Posted on 2020-09-02
4094 SARS-CoV-2 causes severe alveolar inflammation and barrier dysfunction
Deinhardt-Emmer, S.; Böttcher, S.; Häring, C.; Giebeler, L.; Henke, A.; Zell, R.; Hornung, F.; Brandt, C.; Marquet, M.; Mosig, A. S.; Pletz, M. W.; Schacke, M.; Roedel, J.; Heller, R.; Nietzsche, S.; Löffler, B.; Ehrhardt, C.
10.1101/2020.08.31.276725 — microbiology — Posted on 2020-09-02
4097 Structural and functional insights into nitrosoglutathione reductase from Chlamydomonas reinhardtii
Tagliani, A.; Rossi, J.; Marchand, C. H.; de Mia, M.; Tedesco, D.; Libero, G.; Meloni, M.; Falini, G.; Trost, P.; Lemaire, S. D.; Fermani, S.; Zaffagnini, M.
10.1101/2020.08.31.275875 — plant biology — Posted on 2020-09-02
4099 Estimating partial body ionizing radiation exposure by automated cytogenetic biodosimetry
Shirley, B. C.; Knoll, J. H. M.; Moquet, J.; Ainsbury, E.; Duy, P. N.; Norton, F.; Wilkins, R. C.; Rogan, P. K.
10.1101/2020.09.01.278200 — genetics — Posted on 2020-09-02
4106 Induced Disassembly of a Virus-Like Particle under Physiological Conditions for Venom Peptide Delivery
Holford, M.; Napolitano, T.; Anand, P.; Ho, J. S. K.; Jabeen, S.; Kuppan, J.; Manir, S.; Kelly, M. P.
10.1101/2020.09.01.278598 — bioengineering — Posted on 2020-09-02
4109 Genomic signatures of the unjamming transition in compressed human bronchial epithelial cells
De Marzio, M.; Kılıc, A.; Maiorino, E.; Mitchel, J.; McGill, M.; Chase, R.; Fredberg, J. J.; Park, J.-A.; Glass, K.; Weiss, S. T.
10.1101/2020.09.01.277962 — genomics — Posted on 2020-09-02
4115 A Human Multi-Lineage Hepatic Organoid Model for Liver Fibrosis
GUAN, Y.; Enejder, A.; Wang, M.; Fang, Z.; Cui, L.; Chen, S.-Y.; Wang, J.; Tan, Y.; Wu, M.; Chen, X.; Johansson, P. K.; Osman, I.; Kunimoto, K.; Russo, P.; Heilshorn, S. C.; Peltz, G.
10.1101/2020.09.01.278473 — cell biology — Posted on 2020-09-02
4117 Tet2 Controls Beta cells Responses to Inflammation in Type 1 Diabetes
Rui, J.; Deng, S.; Ponath, G.; Kursawe, R.; Lawlor, N.; Sumida, T.; Levine-Ritterman, M.; Perdigoto, A. L.; Stitzel, M. L.; Pitt, D. L.; Lu, J.; Herold, K. C.
10.1101/2020.09.01.278028 — immunology — Posted on 2020-09-02
4118 Dynamic fluctuations of the locus coeruleus-norepinephrine system underlie sleep state transitions
Kjaerby, C.; Andersen, M.; Hauglund, N. L.; Ding, F.; Wang, W.; Xu, Q.; Deng, S.; Kang, N.; Peng, S.; Sun, Q.; Dall, C.; Joergensen, P. K.; Feng, J.; Li, Y.; Weikop, P.; Hirase, H.; Nedergaard, M.
10.1101/2020.09.01.274977 — neuroscience — Posted on 2020-09-02
4126 Self-similar action potential cycle-to-cycle variability of Ca2+ and current oscillators in cardiac pacemaker cells
Yang, D.; Lyashkov, A. E.; Morrell, C. H.; Zahanich, I.; Yaniv, Y.; Vinogradova, T. M.; Ziman, B. D.; Maltsev, V. A.; Lakatta, E. G.
10.1101/2020.09.01.277756 — biophysics — Posted on 2020-09-02
4128 Computationally assisted design and selection of maneuverable biological walking machines
Wang, J.; Park, J.; Zhang, X.; Park, I.; Kilicarslan, E. A.; Kim, Y.; Bashir, R.; Gazzola, M.
10.1101/2020.09.01.278622 — bioengineering — Posted on 2020-09-02
4129 BonA from Acinetobacter baumannii forms a divisome-localized decamer that supports outer envelope function
Grinter, R.; Morris, F. C.; Dunstan, R. A.; Leung, P. M.; Belousoff, M.; Gunasinghe, S. D.; Beckham, S.; Peleg, A. Y.; Greening, C.; Li, J.; Heinz, E.; Lithgow, T.
10.1101/2020.09.01.278697 — biochemistry — Posted on 2020-09-02
4130 SLEAP: Multi-animal pose tracking
Pereira, T. D.; Tabris, N.; Li, J.; Ravindranath, S.; Papadoyannis, E. S.; Wang, Z. Y.; Turner, D. M.; McKenzie-Smith, G.; Kocher, S. D.; Falkner, A. L.; Shaevitz, J. W.; Murthy, M.
10.1101/2020.08.31.276246 — animal behavior and cognition — Posted on 2020-09-02
4135 Metabolic profiling reveals nutrient preferences during carbon utilization in Bacillus species
Chang, J. D.; Vaughan, E. E.; Gu Liu, C.; Jelinski, J. W.; Terwilliger, A. L.; Maresso, A. W.
10.1101/2020.09.01.277376 — microbiology — Posted on 2020-09-01
4141 Host infection by the grass-symbiotic fungus Epichloë festucaerequires catalytically active H3K9 and H3K36 methyl transferases
Lukito, Y.; Lee, K.; Noorifar, N.; Green, K.; Winter, D.; Ram, A.; Hale, T.; Chujo, T.; Cox, M.; Johnson, L.; Scott, B.
10.1101/2020.09.01.277384 — genetics — Posted on 2020-09-01
4145 Disulfiram inhibits M. tuberculosis growth by altering methionine pool, redox status and host-immune response
Chaudhary, D.; Marzuki, M.; Lee, A.; Bouzeyen, R.; Singh, A.; Gosain, T. P.; Kidwai, S.; Grady, C.; Tsotetsi, K.; Chawla, K.; Shihui, F.; Lum, J.; Gupta, S. K.; Agarwal, N.; Tsenova, L.; Kumar, Y.; Lee, B.; Kumar, P.; Thakur, K. G.; Singh, R.; Singhal, A.
10.1101/2020.09.01.277368 — microbiology — Posted on 2020-09-01
4146 Favipiravir-resistant influenza A virus shows potential for transmission
Goldhill, D.; Yan, A.; Frise, R.; Zhou, J.; Shelley, J.; Gallego-Cortes, A.; Miah, S.; Akinbami, O.; Galiano, M.; Zambon, M.; Lackenby, A.; Barclay, W. S.
10.1101/2020.09.01.277343 — microbiology — Posted on 2020-09-01
4148 An important role of the interplay between Bdnf transcription and histone acetylation in epileptogenesis
Magalska, A.; Walczak, A.; Czaban, I.; Skupien, A.; Pels, K. K.; Szczepankiewicz, A. A.; Krawczyk, K.; Ruszczycki, B.; Wilczynski, G. M.; Dzwonek, J.
10.1101/2020.09.01.277327 — neuroscience — Posted on 2020-09-01
4149 Meaningful Effects in the Adolescent Brain Cognitive Development Study
Dick, A. S.; Watts, A. L.; Heeringa, S. G.; Lopez, D. A.; Bartsch, H.; Fan, C. C.; Palmer, C. E.; Reuter, C.; Marshall, A. T.; Haist, F.; Hawes, S.; Nichols, T.; Barch, D. M.; Jernigan, T. L.; Garavan, H.; Grant, S.; Pariyadath, V.; Hoffman, E.; Neale, M.; Paulus, M. P.; Sher, K.; Thompson, W.
10.1101/2020.09.01.276451 — neuroscience — Posted on 2020-09-01
4151 Gradual development of non-adjacent dependency learning during early childhood
Paul, M.; Maennel, C.; van der Kant, A.; Mueller, J. L.; Hoehle, B.; Wartenburger, I.; Friederici, A. D.
10.1101/2020.09.01.277822 — neuroscience — Posted on 2020-09-01
4156 Optimising biomedical relationship extraction with BioBERT: Best practices for data creation
Giles, O.; Karlsson, A.; Masiala, S.; White, S.; Cesareni, G.; Perfetto, L.; Mullen, J.; Hughes, M.; Harland, L.; Malone, J.
10.1101/2020.09.01.277277 — bioinformatics — Posted on 2020-09-01
4167 Molecular underpinnings of ssDNA specificity by Rep HUH endonucleases and implications for HUH-tag multiplexing and engineering
Tompkins, K. J.; Houtti, M.; Litzau, L. A.; Aird, E. J.; Everett, B. A.; Nelson, A. T.; Pornschloegl, L.; Limon-Swanson, L. K.; Evans, R. L.; Evans, K.; Shi, K.; Aihara, H.; Gordon, W. R.
10.1101/2020.09.01.278671 — biophysics — Posted on 2020-09-01
4168 High Throughput Computational Mouse Genetic Analysis
Arslan, A.; GUAN, Y.; Chen, X.; Zhu, W.; Wu, M.; Zheng, M.; Dill, D. L.; Peltz, G.; Donaldson, R.; Ford, M.
10.1101/2020.09.01.278465 — bioinformatics — Posted on 2020-09-01
4169 Tapping into a phospholipid-LRH-1 axis yields a powerful anti-inflammatory agent with in vivo activity against colitis
Mays, S. G.; D'Agostino, E. H.; Flynn, A. R.; Huang, X.; Wang, G.; Liu, X.; Millings, E. J.; Okafor, C. D.; Patel, A.; Cato, M. L.; Cornelison, J. L.; Melchers, D.; Houtman, R.; Moore, D. D.; Calvert, J. W.; Jui, N. T.; Ortlund, E. A.
10.1101/2020.09.01.278291 — biochemistry — Posted on 2020-09-01
4170 Chiral evasion and stereospecific antifolate resistance in Staphylococcus aureus
Wang, S.; Reeve, S. M.; Ojewole, A. A.; Frenkel, M. S.; Holt, G. T.; Gainza, P.; Keshipeddy, S.; Fowler, V. G.; Wright, D. L.; Donald, B. R.
10.1101/2020.07.28.224667 — biochemistry — Posted on 2020-09-01
4172 Secondary ossification center induces and protects growth plate structure
Xie, M.; Goldin, P.; Herdina, A. N.; Estefa, J.; Medvedeva, E.; Li, L.; Newton, P.; Kotova, S.; Shavkuta, B.; Saxena, A.; Shumate, L.; Metscher, B.; Groschmidt, K.; Nishimori, S.; Akovantseva, A.; Usanova, A. P.; Kurenkova, A. D.; Kumar, A.; Arregui, I. L.; Tafforeau, P.; Fried, K.; Carlstrom, M.; Simon, A.; Gasser, C.; Kronenberg, H.; Bastepe, M.; Cooper, K.; Timashev, P.; Sanchez, S.; Adameyko, I.; Eriksson, A.; Chagin, A. S.
10.1101/571612 — evolutionary biology — Posted on 2020-09-01
4177 PxdA interacts with the DipA phosphatase to regulate endosomal hitchhiking of peroxisomes
Salogiannis, J.; Christensen, J. R.; Aguilar-Maldonado, A.; Shukla, N.; Reck-Peterson, S. L.
10.1101/2020.02.03.932616 — cell biology — Posted on 2020-09-01
4178 Membrane-type 1 matrix metalloproteinase (MMP-14) modulates tissue homeostasis by a non-proteolytic mechanism
Attur, M. G.; Lu, C.; Zhang, X.; Han, T.; Alexandre, C.; Valacca, C.; Zheng, S.; Meikle, S.; Brukner Dabovic, B.; Tassone, E.; Yang, Q.; Kolupaeva, V.; Yakar, S.; Abramson, S. B.; Mignatti, P.
10.1101/631739 — cell biology — Posted on 2020-09-01
4182 Integrative computational approach identifies new targets in CD4+ T cell-mediated immune disorders
Puniya, B. L.; Amin, R.; Lichter, B.; Moore, R.; Ciurej, A.; Townsend, S.; Shah, A. R.; Barberis, M.; Helikar, T.
10.1101/2020.01.02.893164 — systems biology — Posted on 2020-09-01
4183 Characterization of novel pollen-expressed transcripts reveals their potential roles in pollen heat stress response in Arabidopsis thaliana.
Rutley, N.; Poidevin, L.; Doniger, T.; Tillet, R. L.; Rath, A.; Forment, J.; Schlauch, K.; Luria, G.; Ferrando, A.; Harper, J. F.; Miller, G.
10.1101/2020.08.20.258764 — plant biology — Posted on 2020-09-01
4184 Two distinct phases of chloroplast biogenesis during de-etiolation in Arabidopsis thaliana
Pipitone, R.; Eicke, S.; Pfister, B.; Glauser, G.; Falconet, D.; Uwizeye, C.; Pralon, T.; Zeeman, S.; Kessler, F.; Demarsy, E.
10.1101/2020.08.30.274043 — plant biology — Posted on 2020-09-01
4185 Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment
Baryawno, N.; Kfoury, Y.; Severe, N.; Mei, S.; Gustafsson, K. U.; Hirz, T.; Brouse, T.; Scadden, E.; Choi, B.; Barkas, N.; Shin, J.; Saylor, P.; Scadden, D.; Sykes, D.; Kharchenko, P.
10.1101/2020.03.19.998658 — cancer biology — Posted on 2020-09-01
4187 Combination of photoactivation with lattice light-sheet imaging allows visualizing complex dorsal ruffling dynamics
Leyden, F.; Uthistran, S.; Moorthi, U. K.; York, H. M.; Patil, A.; Gandhi, H.; Petrov, E. P.; Arumugam, S.
10.1101/2020.09.01.276824 — biophysics — Posted on 2020-09-01
4189 Tissue specificity-aware TWAS (TSA-TWAS) framework identifies novel associations with metabolic, immunologic, and virologic traits in HIV-positive adults
Li, B.; Veturi, Y.; Verma, A.; Bradford, Y.; Daar, E. S.; Gulick, R. M.; Riddler, S. A.; Robbins, G. K.; Lennox, J. L.; Haas, D. W.; Ritchie, M. D.
10.1101/2020.08.31.273458 — bioinformatics — Posted on 2020-09-01
4193 A rapid, accurate approach to inferring pedigrees in endogamous populations
Williams, C. M.; Scelza, B.; Daya, M.; Lange, E.; Gignoux, C. R.; Henn, B. M.
10.1101/2020.02.25.965376 — bioinformatics — Posted on 2020-09-01
4195 Substrate-dependent suppression of oxidative phosphorylation in the Frataxin-depleted heart
Vasquez, C.; Patel, M.; Sivaramakrishnan, A.; Bekeova, C.; Anderson-Pullinger, L.; Wang, N.; Seifert, E. L.
10.1101/2020.06.12.148361 — biochemistry — Posted on 2020-09-01
4198 eEF2 kinase enhances the expression of PD-L1 by promoting the translation of its mRNA
Proud, C. G.; Wu, Y.; Xie, J.; Jin, X.; Lenchine, R. V.; Wang, X.; Fang, D. M. W.; NASSAR, Z.; Butler, L. M.; Li, J.
10.1101/2020.09.01.278655 — biochemistry — Posted on 2020-09-01
4200 Modulation of Siglec-7 Signaling via in situ Created High-affinity cis-Ligands
Hong, S.; Yu, C.; Shi, Y.; Wang, P.; Chapla, D. G.; Rodrigues, E.; Moremen, K. W.; Paulson, J. C.; Macauley, M. S.; Wu, P.
10.1101/2020.07.15.203125 — biochemistry — Posted on 2020-09-01
4210 Negeviruses reduce replication of alphaviruses during co-infection
Patterson, E. I.; Kautz, T. F.; Contreras-Gutierrez, M. A.; Guzman, H.; Tesh, R. B.; Hughes, G. L.; Forrester, N. L.
10.1101/2020.09.01.277517 — microbiology — Posted on 2020-09-01
4211 Prophylactic Application of Tailocins Prevents Infection by Pseudomonas syringae
Baltrus, D. A.; Clark, M.; Hockett, K. L.; Mollico, M.; Smith, C.; Weaver, S.
10.1101/2020.08.31.276642 — microbiology — Posted on 2020-09-01
4216 High transmissibility and fetal pathogenicity of recent Zika virus strains from the African lineage
Aubry, F.; Jacobs, S.; Darmuzey, M.; Lequime, S.; Delang, L.; Fontaine, A.; Jupatanakul, N.; Miot, E. F.; Dabo, S.; Manet, C.; Montagutelli, X.; Baidaliuk, A.; Gambaro, F.; Simon-Loriere, E.; Gilsoul, M.; Romero-Vivas, C. M.; Cao-Lormeau, V.-M.; Jarman, R. G.; Diagne, C. T.; Faye, O.; Faye, O.; Sall, A. A.; Neyts, J.; Nguyen, L.; Kaptein, S. J. F.; Lambrechts, L.
10.1101/2020.09.01.277673 — microbiology — Posted on 2020-09-01
4219 Impact of Rap-Phr system abundance on adaptation of Bacillus subtilis
Gallegos-Monterrosa, R.; Nordgaard Christensen, M.; Barchewitz, T.; Koeppenhoefer, S.; Priyadarshini, B.; Balint, B.; Maroti, G.; Kempen, P. J.; Dragos, A.; Kovacs, A. T.
10.1101/2020.09.01.278184 — microbiology — Posted on 2020-09-01
4220 Calcium-dependent protein acyltransferase DHHC21 controls activation of CD4+ T cells
Shayahati, B.; Fan, Y.; West, S.; Tewari, R.; Ko, J.; Mills, T.; Boehning, D.; Akimzhanov, A.
10.1101/2020.09.01.277947 — immunology — Posted on 2020-09-01
4221 Phenotypic and clonal stability of antigen-inexperienced memory-like T cells across the genetic background, hygienic status, and aging
Moudra, A.; Niederlova, V.; Novotny, J.; Schmiedova, L.; Kubovciak, J.; Matejkova, T.; Drobek, A.; Pribikova, M.; Stopkova, R.; Cizkova, D.; Neuwirth, A.; Michalik, J.; Krizova, K.; Hudcovic, T.; Kolar, M.; Kozakova, H.; Kreisinger, J.; Stopka, P.; Stepanek, O.
10.1101/2020.09.01.277004 — immunology — Posted on 2020-09-01
4224 PhosR enables processing and functional analysis of phosphoproteomic data
Kim, J. H.; Kim, T.; Hoffman, N.; Xiao, D.; James, D. E.; Humphrey, S.; Yang, P.
10.1101/2020.08.31.276329 — systems biology — Posted on 2020-09-01
4225 Integrating Proteomes for Lung Tissue and Lavage Reveals Pathways that Link Responses in Allergen-Challenged Mice
Mahood, T. H.; Pascoe, C. D.; Karakach, T. K.; Jha, A.; Basu, S.; Ezatti, P.; Spicer, V.; Mookherjee, N.; Halayko, A. J.
10.1101/2020.01.14.905737 — systems biology — Posted on 2020-09-01
4229 The study of lumbar ligamentum flavum hypertrophy induced in bipedal mice
Zheng, Z.; Qian, L.; Ao, X.; Li, P.; Peng, Y.; Chu, J.; Jiang, T.; Zhang, Z.; Wang, L.
10.1101/723239 — biophysics — Posted on 2020-09-01
4230 THE MODEL OF PPARγ DOWNREGULATED SIGNALING IN PSORIASIS
Sobolev, V.; Soboleva, A.; Svitich, O.; Dvoriankova, E.; Piruzyan, A.; Mildzikhova, D.; Korsunskaya, I.; Nesterova, A.
10.1101/2020.09.01.274753 — bioinformatics — Posted on 2020-09-01
4232 Besca, a single-cell transcriptomics analysis toolkit to accelerate translational research
Maedler, S. C.; Julien-Laferriere, A.; Wyss, L.; Phan, M.; Kang, A. S. W.; Ulrich, E.; Schmucki, R.; Zhang, J. D.; Ebeling, M.; Badi, L.; Kam-Thong, T.; Schwalie, P. C.; Hatje, K.
10.1101/2020.08.11.245795 — bioinformatics — Posted on 2020-09-01
4233 Genome-wide effects of the antimicrobial peptide apidaecin on translation termination
Mangano, K.; FLorin, T.; Shao, X.; Klepacki, D.; Chelysheva, I.; Ignatova, Z.; Gao, Y.; Mankin, A.; Vazquez-Laslop, N.
10.1101/2020.05.17.100735 — biochemistry — Posted on 2020-09-01
4235 Jumping back and forth: anthropozoonotic and zoonotic transmission of SARS-CoV-2 on mink farms
Oude Munnink, B. B.; Sikkema, R. S.; Nieuwenhuijse, D. F.; Molenaar, R. J.; Munger, E.; Molenkamp, R.; van der Spek, A.; Tolsma, P.; Rietveld, A.; Brouwer, M.; Bouwmeester-Vincken, N.; Harders, F.; Hakze-van der Honing, R.; Wegdam-Blans, M. C. A.; Bouwstra, R.; GeurtsvanKessel, C.; van der Eijk, A.; Velkers, F.; Smit, L.; Stegeman, A.; van der Poel, W. H. M.; Koopmans, M.
10.1101/2020.09.01.277152 — genomics — Posted on 2020-09-01
4236 Potential malaria vector Anopheles minimus (species A) still persisting in North East India
Tyagi, V.; Goswami, D.; Dhiman, S.; Rabha, B.; Dey, D.; Chattopadhyay, P.; Dwivedi, S. K.
10.1101/2020.09.01.277020 — ecology — Posted on 2020-09-01
4239 The importance of charge in perturbing the aromatic glue stabilizing the protein-protein interface of homodimeric tRNA-guanine transglycosylase
Nguyen, A.; Nguyen, D.; Nguyen, T. X. P.; Sebastiani, M.; Dörr, S.; Hernandez-Alba, O.; Debaene, F.; Cianferani, S.; Heine, A.; Klebe, G.; Reuter, K.
10.1101/2020.09.01.277731 — molecular biology — Posted on 2020-09-01
4240 Variation in the Gut Microbiota of Common Marmosets: Differences with Colony of Origin and Integration
Cooper, R. E.; Mangus, L. M.; Lynch, J.; Schonvisky, K.; Wright, J.; McLimans, C. J.; Wong, H. T.; Chen See, J. R.; Lamendella, R.; Mankowski, J. L.
10.1101/2020.08.31.276733 — microbiology — Posted on 2020-09-01
4242 An Approach to Automatically Label & Order Brain Activity/Component Maps
Salman, M. S.; Wager, T. D.; Damaraju, E. C.; Abrol, A.; Calhoun, V. D.
10.1101/2020.08.31.275578 — neuroscience — Posted on 2020-09-01
4245 Coupled Control of Distal Axon Integrity and Somal Responses to Axonal Damage by the Palmitoyl Acyltransferase ZDHHC17
Niu, J.; Sanders, S.; Jeong, H.-K.; Holland, S.; Sun, Y.; Collura, K.; Hernandez, L.; Huang, H.; Hayden, M. R.; Smith, G.; Hu, Y.; Jin, Y.; Thomas, G.
10.1101/2020.09.01.276287 — neuroscience — Posted on 2020-09-01
4246 SNT: A Unifying Toolbox for Quantification of Neuronal Anatomy
Arshadi, C.; Günther, U. A.; Eddison, M.; Harrington, K. I.; Ferreira, T. A.
10.1101/2020.07.13.179325 — neuroscience — Posted on 2020-09-01
4247 Insulin enhances presynaptic glutamate release via opioid receptor-mediated disinhibition
Fetterly, T. L.; Oginsky, M. F.; Nieto, A. M.; Alonso-Caraballo, Y.; Santana-Rodriguez, Z.; Ferrario, C.
10.1101/517797 — neuroscience — Posted on 2020-09-01
4248 Engineering high-yield biopolymer secretion creates an extracellular protein matrix for living materials
Charrier, M.; Orozco-Hidalgo, M. T.; Tjahjono, N.; Li, D.; Molinari, S.; Ryan, K. R.; Ashby, P. D.; Rad, B.; Ajo-Franklin, C.
10.1101/2020.08.31.276303 — synthetic biology — Posted on 2020-09-01
4250 Strong reduction of the chain rigidity of hyaluronan by selective binding of Ca2+ ions
Giubertoni, G.; Perez de Alba Ortiz, A.; BAano, F.; Zhang, X.; Linhard, B. J.; Green, D. E.; DeAngelis, P.; Koenderink, G. H.; Richter, R.; Ensing, B.; Bakker, H. J.
10.1101/2020.09.01.277194 — biochemistry — Posted on 2020-09-01
4251 High-Quality Genome Assembly and Annotation of the California Harvester Ant Pogonomyrmex californicus (Buckley, 1867)
Bohn, J.; Halabian, R.; Schrader, L.; Shabardina, V.; Stefffen, R.; Suzuki, Y.; Ernst, U. R.; Gadau, J. R.; Makalowski, W.
10.1101/2020.09.01.277236 — genomics — Posted on 2020-09-01
4252 Biallelic mutation of CLRN2 causes non-syndromic hearing loss in humans
Vona, B.; Mazaheri, N.; Lin, S.-J.; Dunbar, L. A.; Maroofian, R.; Azaiez, H.; Booth, K. T.; Vitry, S.; Rad, A.; Varshney, P.; Fowler, B.; Beetz, C.; Alagramam, K. N.; Murphy, D.; Shariati, G.; Sedaghat, A.; Houlden, H.; VijayKumar, S.; Smith, R. J. H.; Haaf, T.; El-Amraoui, A.; Bowl, M. R.; Varshney, G. K.; Galehdari, H.
10.1101/2020.07.29.222828 — genetics — Posted on 2020-09-01
4253 A Genome-wide CRISPR-Cas9 Screen Identifies Host Factors Essential for Optimal Plasmodium Liver Stage Development.
Vijayan, K.; Arang, N.; Wei, L.; Morrison, R.; Geiger, R.; Parks, R. K.; Lewis, A. J.; Mast, F. D.; Douglass, A. N.; Kain, H. S.; Aitchison, J. D.; Johnson, J. S.; Aderem, A.; Kaushansky, A.
10.1101/2020.08.31.275867 — cell biology — Posted on 2020-09-01
4255 A deeply conserved miR-1 dependent regulon supports muscle cell physiology
Gutierrez-Perez, P.; Santillan, E. M.; Lendl, T.; Schrempf, A. C.; Steinacker, T. L.; Asparuhova, M.; Brandstetter, M.; Haselbach, D.; Cochella, L.
10.1101/2020.08.31.275644 — cell biology — Posted on 2020-09-01
4256 A systematic genetic interaction map of human solute carriers assigns a role to SLC25A51/MCART1 in mitochondrial NAD uptake
Girardi, E.; Fiume, G.; Goldmann, U.; Sin, C.; Mueller, F.; Lindinger, S.; Sedlyarov, V.; Srndic, I.; Agerer, B.; Kartnig, F.; Meixner, E.; Skucha, A.; Rebsamen, M.; Bergthaler, A.; Menche, J.; Superti-Furga, G.
10.1101/2020.08.31.275818 — cell biology — Posted on 2020-09-01
4257 Spir-1 promotes IRF3 activation and is targetted by vaccinia virus protein K7
Torres, A. A.; Macilwee, S. L.; Rashid, A.; Cox, S. E.; Albarnaz, J. D.; Bonjardim, C. A.; Smith, G. L.
10.1101/2020.08.31.276659 — microbiology — Posted on 2020-09-01
4260 Attenuation of homeostatic signaling from apoptotic thymocytes triggers a global regenerative response in the thymus
Kinsella, S.; Evandy, C. A.; Cooper, K.; Iovino, L.; deRoos, P. C.; Hopwo, K. S.; Granadier, D. W.; Smith, C. W.; Rafii, S.; Dudakov, J. A.
10.1101/2020.08.31.275834 — immunology — Posted on 2020-09-01
4261 EEG power spectra and subcortical pathology in chronic disorders of consciousness
Lutkhenoff, E.; Nigri, A.; Rossi Sebastiano, D.; Sattin, D.; Visani, E.; Rosazza, C.; D'Incerti, L.; Bruzzone, M.; Franceschetti, S.; Leonardi, M.; Ferraro, S.; Monti, M. M.
10.1101/695288 — neuroscience — Posted on 2020-09-01
4266 Neither the availability of D2 nor CP43 limits the biogenesis of PSII in tobacco
Fu, H.-Y.; Ghandour, R.; Ruf, S.; Zoschke, R.; Bock, R.; Schoettler, M. A.
10.1101/2020.08.31.272526 — plant biology — Posted on 2020-09-01
4269 Identification of Lysine Isobutyrylation as A New Histone Modification Mark
Zhu, Z.; Han, Z.; Halabelian, L.; Yang, X.; Ding, J.; Zhang, N.; Ngo, L.; Song, J.; Zeng, H.; He, M.; Zhao, Y.; Arrowsmith, C. H.; Luo, M.; Bartlett, M. G.; Zheng, Y. G.
10.1101/2020.08.31.270165 — biochemistry — Posted on 2020-09-01
4272 Multi-modal pooled Perturb-CITE-Seq screens in patient models define novel mechanisms of cancer immune evasion
Frangieh, C. J.; Melms, J. C.; Thakore, P. I.; Geiger-Schuller, K. R.; Ho, P.; Luoma, A. M.; Cleary, B. R.; Malu, S.; Cuoco, M.; Zhao, M.; Rogava, M.; Hovey, L.; Rotem, A.; Bernatche, C.; Wucherpfennig, K. W.; Johnson, B. E.; Rozenblatt-Rosen, O.; Schadendorf, D.; Regev, A.; Izar, B.
10.1101/2020.09.01.267211 — genomics — Posted on 2020-09-01
4273 Global Geographic and Temporal Analysis of SARS-CoV-2 Haplotypes Normalized by COVID-19 Cases during the First Seven Months of the Pandemic
Justo Arevalo, S.; Zapata Sifuentes, D.; Huallpa Robles, C.; Landa Bianchi, G.; Castillo Chavez, A.; Garavito-Salini Casas, R.; Uceda-Campos, G.; Pineda Chavarria, R.
10.1101/2020.07.12.199414 — genomics — Posted on 2020-09-01
4276 Spontaneous rate of clonal mutations in Daphnia galeata
Pfenninger, M.; Binde-Doria, H.; Nickel, J.; Thielsch, A.; Schwenk, K.; Cordellier, M.
10.1101/2020.08.31.275495 — evolutionary biology — Posted on 2020-09-01
4277 Selfing is the safest sex for Caenorhabditis tropicalis
Noble, L. M.; Yuen, J.; Stevens, L.; Moya, N.; Persaud, R. S.; Moscatelli, M. A.; Jackson, J. L.; Braendle, C.; Andersen, E. C.; Seidel, H. S.; Rockman, M. V.
10.1101/2020.08.07.242032 — evolutionary biology — Posted on 2020-09-01
4278 Widespread decline in plant diversity across six decades
Eichenberg, D.; Bowler, D.; Bonn, A.; Bruelheide, H.; Grescho, V.; Harter, D.; Jandt, U.; May, R.; Winter, M.; Jansen, F.
10.1101/2020.08.31.275461 — ecology — Posted on 2020-09-01
4280 Deficient spermiogenesis in mice lacking Rlim
Wang, F.; Gervasi, M. G.; Boskovic, A.; Sun, F.; Rinaldi, V.; Yu, J.; Wallingford, M.; Tourzani, D.; Mager, J.; Zhu, L.; Rando, O.; Visconti, P.; Strittmatter, L.; Bach, I.
10.1101/2020.08.31.275248 — developmental biology — Posted on 2020-09-01
4281 Ciliary signaling-patterned smooth muscle drives tubular elongation
Yang, Y.; Paivinen, P.; Xia, C.; Krup, A. L.; Makela, T. P.; Mostov, K. E.; Reiter, J. F.
10.1101/2020.08.31.276295 — developmental biology — Posted on 2020-09-01
4282 CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy
Giunta, S.; Herve, S.; White, R. R.; Wilhelm, T.; Dumont, M.; Scelfo, A.; Gamba, R.; Wong, C. K.; Rancati, G.; Smogorzewska, A.; Funabiki, H.; Fachinetti, D.
10.1101/2020.09.01.277103 — cell biology — Posted on 2020-09-01
4283 Degradation of ATFS-1 by LONP-1 promotes deleterious mitochondrial genome heteroplasmy
Haynes, C.; Yang, Q.; Liu, P.; Du, Y.; Luk, K.; Anderson, N.; Lavelle, J.; Zeinert, R.; Chien, P.; Wolfe, S.
10.1101/2020.09.01.274472 — cell biology — Posted on 2020-09-01
4285 IL-4-induced hysteresis in naive T cell activation
Meli, A. P.; Wang, Y.; de Kouchkovsky, D. A.; Kong, Y.; Basu, M. K.; Ghosh, S.; Rothlin, C. V.
10.1101/2020.08.31.275842 — immunology — Posted on 2020-09-01
4286 MT5-MMP controls APP metabolism and the fate of beta-CTF/C99 and Abeta through proteolytic-dependent and -independent mechanisms relevant for Alzheimer's disease
Garcia-Gonzalez, L.; Paumier, J.-M.; Louis, L.; Pilat, D.; Bernard, A.; Stephan, D.; Jullien, N.; Checler, F.; Nivet, E.; KHRESTCHATISKY, M.; Baranger, K.; Rivera, S.
10.1101/2020.09.01.258665 — neuroscience — Posted on 2020-09-01
4291 Reduced anterior cingulate cortex volume induced by chronic stress correlates with increased behavioral emotionality and decreased synaptic puncta density
Misquitta, K. A.; Miles, A.; Prevot, T. D.; Knoch, J. K.; Fee, C.; Newton, D. F.; Ellegood, J.; Lerch, J. P.; Sibille, E.; Nikolova, Y.; Banasr, M.
10.1101/2020.08.31.275750 — neuroscience — Posted on 2020-09-01
4292 Disrupting the ArcA regulatory network increases tetracycline susceptibility of TetR Escherichia coli
Arrieta-Ortiz, M. L.; Pan, M.; Kaur, A.; Srinivas, V.; Dash, A.; Immanuel, S. R. C.; Baliga, N. S.
10.1101/2020.08.31.275693 — systems biology — Posted on 2020-09-01
4294 Evaluation of the effect of SiO2 and Fe3O4 nanoparticles on Pisum sativum seeds in laboratory and field experiments
Galaktionova, L. V.; Lebedev, S. V.; Terekhova, N. A.; Voskobulova, N. I.; Korotkova, A. M.; Vershinina, I. A.
10.1101/2020.08.31.275859 — plant biology — Posted on 2020-09-01
4295 Towards establishing no observed adverse effect levels (NOAEL) for different sources 1 of dietary phosphorus in feline adult diets: results from a 7 month feeding study
Coltherd, J. C.; Alexander, J.; Pink, C.; Rawlings, J.; Haydock, R.; Carvell-Miller, L. J.; Butterwick, R. F.; Logan, D. W.; Watson, P.; Bakke, A. M.; Elliott, J.; Molina, L.; Biourge, V.
10.1101/2020.09.01.276907 — pharmacology and toxicology — Posted on 2020-09-01
4296 Extreme stiffness of neuronal synapses and implications for synaptic adhesion and plasticity
Yang, J.; Mandriota, N.; Harrellson, S. G.; Jones-Molina, J. A.; Yuste, R.; Lefort, R.; Sahin, O.
10.1101/2020.08.31.273466 — biophysics — Posted on 2020-09-01
4298 Regression plane concept: analysing continuous cellular processes with machine learning
Abel, S.; Piccinini, F.; Beleon, A.; Balassa, T.; Varga, I. G.; Migh, E.; Paavolainen, L.; Timonen, S.; Banerjee, I.; Yamauchi, Y.; Ando, I.; Peltonen, J.; Pietiainen, V.; Honti, V.; Horvath, P.
10.1101/2020.09.01.276089 — bioinformatics — Posted on 2020-09-01
4300 White matter tract-oriented deformation is dependent on real-time axonal fiber orientation
Zhou, Z.; Domel, A. G.; Li, X.; Grant, G.; Kleiven, S.; Camarillo, D.; Zeineh, M.
10.1101/2020.09.01.271502 — bioengineering — Posted on 2020-09-01
4303 Discovery of Drug-like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3
Virdi, R. S.; Bavisotto, R. V.; Hopper, N. C.; Vuksanovic, N.; Melkonian, T. R.; Silvaggi, N. R.; Frick, D.
10.1101/2020.07.06.190413 — biochemistry — Posted on 2020-09-01
4305 Ongoing evolution of KRAB zinc finger protein-coding genes in modern humans
Thorball, C. W.; Planet, E.; de Tribolet-Hardy, J.; Coudray, A.; Fellay, J.; Turelli, P.; Trono, D.
10.1101/2020.09.01.277178 — genomics — Posted on 2020-09-01
4306 Molecular and evolutionary mechanisms of yeast thermotolerance
Abrams, M. B.; Dubin, C. A.; AlZaben, F.; Bravo, J.; Joubert, P. M.; Weiss, C. V.; Brem, R. B.
10.1101/2020.08.31.275453 — evolutionary biology — Posted on 2020-09-01
4307 Chromatin-associated effectors of energy-sensing pathways mediate intergenerational effects
Pires da Silva, A.; Robles, P.; Zuco, G.; Paganapoulou, P.; Hill, B.; Kache, V.; Bateson, C.; Turner, A.
10.1101/2020.08.31.275727 — developmental biology — Posted on 2020-09-01
4308 Flagellar energetics from high-resolution imaging of beating patterns in tethered mouse sperm
Nandagiri, A.; Gaikwad, A. S.; Potter, D. L.; Nosrati, R.; Soria, J.; O'Bryan, M. K.; Jadhav, S.; Prabhakar, R.
10.1101/2020.08.31.269340 — cell biology — Posted on 2020-09-01
4309 Molecular Mechanism of Nuclear Tau Accumulation and its Role in Protein Synthesis.
Portillo, M.; Eremenko, E.; Kaluski, S.; Onn, L.; Stein, D.; Slobodnik, Z.; Ueberham, U.; Einav, M.; Bruckner, M. K.; Arendt, T.; Toiber, D.
10.1101/2020.09.01.276782 — molecular biology — Posted on 2020-09-01
4311 A versatile reporter system to monitor virus infected cells and its application to dengue virus and SARS-CoV-2
Pahmeier, F.; Neufeldt, C. J.; Cerikan, B.; Prasad, V.; Pape, C.; Laketa, V.; Ruggieri, A.; Bartenschlager, R.; Cortese, M.
10.1101/2020.08.31.276683 — microbiology — Posted on 2020-09-01
4312 Spatially-targeted proteomics of the host-pathogen interface during staphylococcal abscess formation
Guiberson, E.; Weiss, A.; Ryan, D. J.; Monteith, A. J.; Sharman, K.; Gutierrez, D. B.; Perry, W. J.; Caprioli, R. M.; Skaar, E. P.; Spraggins, J. M.
10.1101/2020.09.01.267773 — microbiology — Posted on 2020-09-01
4314 Drug repurposing screen identifies masitinib as a 3CLpro inhibitor that blocks replication of SARS-CoV-2 in vitro
Drayman, N.; Jones, K. A.; Azizi, S.-A.; Froggatt, H. M.; Tan, K.; Ivanova Maltseva, N.; Chen, S.; Nicolaescu, V.; Dvorkin, S.; Furlong, K.; Kathayat, R. S.; Firpo, M. R.; Mastrodomenico, V.; Bruce, E. A.; Schmidt, M. M.; Jedrzejczak, R.; Munoz-Alia, M. A.; Schuster, B.; Nair, V.; Botten, J. W.; Brooke, C. B.; Baker, S. C.; Mounce, B. C.; Heaton, N. S.; Dickinson, B. C.; Jaochimiak, A.; Randall, G.; Tay, S.
10.1101/2020.08.31.274639 — microbiology — Posted on 2020-09-01
4315 Serum proteomic profiling at diagnosis predicts clinical course, and need for intensification of treatment in inflammatory bowel disease.
Kalla, R.; Adams, A. T.; Bergemalm, D.; Vatn, S.; Kennedy, N. A.; Ricanek, P.; Lindstrom, J. C.; Ocklind, A.; Hjelm, F.; Ventham, N. T.; Ho, G.-T.; Petren, C.; IBD Character Consortium, ; Repsilber, D.; Soderholm, J. D.; Pierik, M.; D'Amato, M.; Gomollon, F.; Olbjorn, C.; Jahnsen, J.; Vatn, M. H.; Halfvarson, J.; Satsangi, J.
10.1101/2020.08.31.276162 — immunology — Posted on 2020-09-01
4316 Characterization of neutralizing versus binding antibodies and memory B cells in COVID-19 recovered individuals from India
Nayak, K.; Gottimukkala, K.; Kumar, S.; Reddy, E. S.; Edara, V. V.; Kauffman, R.; Floyd, K.; Mantus, G.; Savargaonkar, D.; Goel, P. K.; Arora, S.; Rahi, M.; Davis, C. W.; Linderman, S.; Wrammert, J.; Suthar, M.; Ahmed, R.; Sharma, A.; Murali-Krishna, K.; Chandele, A.
10.1101/2020.08.31.276675 — immunology — Posted on 2020-09-01
4317 Engineered Trimeric ACE2 Binds and Locks "Three-up" Spike Protein to Potently Inhibit SARS-CoVs and Mutants
Guo, L.; Bi, W.; Wang, X.; Xu, W.; Yan, R.; Zhang, Y.; Zhao, K.; Li, Y.; Zhang, M.; Bao, X.; Cai, X.; Li, Y.; Qu, D.; Jiang, S.; Xie, Y.; Zhou, Q.; Lu, L.; Dang, B.
10.1101/2020.08.31.274704 — bioengineering — Posted on 2020-09-01
4320 In silico Drosophila Patient Model Reveals Optimal Combinatorial Therapies for Colorectal Cancer
Chaudhary, S. U.; Gondal, M. N.; Butt, R. N.; Shah, O. S.; Nasir, Z.; Hussain, R.; Khawar, H.; Tariq, M.; Faisal, A.
10.1101/2020.08.31.274829 — systems biology — Posted on 2020-09-01
4323 Climate change alters plant-herbivore interactions
Hamann, E.; Blevins, C.; Franks, S.; Jameel, M. I.; Anderson, J.
10.1101/2020.08.31.275164 — plant biology — Posted on 2020-09-01
4325 Social groups buffer maternal loss in mountain gorillas
Morrison, R. E.; Eckardt, W.; Colchero, F.; Vecellio, V.; Stoinski, T. S.
10.1101/2020.09.01.276956 — evolutionary biology — Posted on 2020-09-01
4329 Identification of activity-dependent EGR3 target genes reveals genes associated with DNA damage response and schizophrenia
Marballi, K. K.; Alganem, K.; Brunwasser, S. J.; Barkatullah, A.; Meyers, K. T.; Campbell, J. M.; Mccullumsmith, R. E.; Gallitano, A. L.
10.1101/2020.09.01.276626 — neuroscience — Posted on 2020-09-01
4330 Reduction of Glut1 in retinal neurons but not the RPE alleviates polyol accumulation and normalizes early characteristics of diabetic retinopathy.
Holoman, N. C.; Aiello, J. J.; Trobenter, T. D.; Tarchick, M. J.; Kozlowski, M. R.; Makowski, E. R.; De Vivo, D. C.; Singh, C.; Sears, J. E.; Samuels, I. S.
10.1101/2020.08.31.275230 — neuroscience — Posted on 2020-09-01
4331 A deep learning toolbox for noise-optimized, generalized spike inference from calcium imaging data
Rupprecht, P.; Carta, S.; Hoffmann, A.; Echizen, M.; Kitamura, K.; Helmchen, F.; Friedrich, R. W.
10.1101/2020.08.31.272450 — neuroscience — Posted on 2020-09-01
4332 Experience-dependent structural plasticity in the adult brain: How the learning brain grows.
Schmidt, S.; Gull, S.; Herrmann, K.-H.; Boehme, M.; Irintchev, A.; Urbach, A.; Reichenbach, J. R.; Klingner, C. M.; Gaser, C.; Witte, O. W.
10.1101/2020.09.01.277467 — neuroscience — Posted on 2020-09-01
4333 Low-level, prediction-based sensory and motor processesare unimpaired in Autism
Finnemann, J. J. S.; Plaisted-Grant, K.; Moore, J.; Teufel, C.; Fletcher, P.
10.1101/2020.09.01.277160 — neuroscience — Posted on 2020-09-01
4334 Maternal Transfer of Environmentally Relevant Polybrominated Diphenyl Ethers (PBDEs) Produces a Diabetic Phenotype and Disrupts Glucoregulatory Hormones and Hepatic Endocannabinoids in Adult Mouse Female Offspring
Kozlova, E. V.; Chinthirla, B. D.; Perez, P. A.; DiPatrizio, N. V.; Argueta, D. A.; Phillips, A. L.; Stapleton, H. M.; Gonzalez, G. M.; Krum, J. M.; Carrillo, V.; Bishay, A. E.; Basappa, K. R.; Curras-Collazo, M. C.
10.1101/2020.08.31.275008 — physiology — Posted on 2020-09-01
4335 Tissue specificity-aware TWAS (TSA-TWAS) framework identifies novel associations with metabolic, immunologic, and virologic traits in HIV-positive adults
Li, B.; Veturi, Y.; Verma, A.; Bradford, Y.; Daar, E. S.; Gulick, R. M.; Riddler, S. A.; Robbins, G. K.; Lennox, J. L.; Haas, D. W.; Ritchie, M. D.
10.1101/2020.08.31.273458 — bioinformatics — Posted on 2020-09-01
4336 Statistical Integration of Multiple Omics Datasets Using GO2PLS
Gu, Z.; el Bouhaddani, S.; Pei, J.; Houwing-Duistermaat, J.; Uh, H.-W.
10.1101/2020.08.31.274175 — bioinformatics — Posted on 2020-09-01
4338 The germline mutational process in rhesus macaque and its implications for phylogenetic dating
Bergeron, L. A.; Besenbacher, S.; Bakker, J.; Zheng, J.; Li, P.; Pacheco, G.; Sinding, M.-H. S.; Kamilari, M.; Gilbert, M. T. P.; Schierup, M. H.; Zhang, G.
10.1101/2020.06.22.164178 — evolutionary biology — Posted on 2020-09-01
4340 Two voltage-dependent currents can explain the functional diversity of embryonic Renshaw cells.
Boeri, J.; Meunier, C.; Le Corronc, H.; Branchereau, P.; Timofeeva, Y.; Lejeune, F.-X.; Mouffle, C.; Arulkandarajah, H.; Mangin, J. M.; Legendre, P.; Czarnecki, A.
10.1101/2020.06.18.158931 — neuroscience — Posted on 2020-09-01
4342 Social networks predict the life and death of honey bees
Wild, B.; Dormagen, D. M.; Zachariae, A.; Smith, M. L.; Traynor, K. S.; Brockmann, D.; Couzin, I. D.; Landgraf, T.
10.1101/2020.05.06.076943 — animal behavior and cognition — Posted on 2020-09-01
4344 Pairs of amino acids at the P- and A-sites of the ribosome predictably and causally modulate translation-elongation rates
Ahmed, N.; Friedrich, U. A.; Sormanni, P.; Ciryam, P.; Altman, N. S.; Bukau, B.; Kramer, G.; O'Brien, E. P.
10.1101/2020.04.20.051839 — molecular biology — Posted on 2020-09-01
4345 The rhizosphere metabolome triggers species-specific and context-dependent root responses in later arriving plants
Delory, B. M.; Schempp, H.; Spachmann, S. M.; Störzer, L.; van Dam, N. M.; Temperton, V. M.; Weinhold, A.
10.1101/2020.09.01.276840 — ecology — Posted on 2020-09-01
4346 Plankton Planet: 'seatizen' oceanography to assess open ocean life at the planetary scale
de Vargas, C.; Pollina, T.; Romac, S.; Le Bescot, N.; Henry, N.; Berger, C.; Colin, S.; Haentjens, N.; Carmichael, M.; Le Guen, D.; Decelle, J.; Mahe, F.; Malpot, E.; Beaumont, C.; Hardy, M.; Guiffant, D.; Probert, I.; Gruber, D.; Allen, A.; Gorsky, G.; Follows, M.; Cael, B.; Pochon, X.; Trouble, R.; Lombard, F.; Boss, E.; Prakash, M.
10.1101/2020.08.31.263442 — ecology — Posted on 2020-09-01
4347 Genome-wide identification of tomato xylem sap fitness factors for Ralstonia pseudosolanacearum and Ralstonia syzygii
Georgoulis, S. J.; Shalvarjian, K. E.; Helmann, T. C.; Hamilton, C. D.; Carlson, H.; Deutschbauer, A. M.; Lowe-Power, T. M.
10.1101/2020.08.31.276741 — microbiology — Posted on 2020-09-01
4348 NAD(H)-mediated tetramerization controls the activity of Legionella pneumophila phospholipase PlaB
Diwo, M.; Michel, W.; Aurass, P.; Kuhle-Keindorf, K.; Pippel, J.; Krausze, J.; Lang, C.; Blankenfeldt, W.; Flieger, A.
10.1101/2020.09.01.246603 — microbiology — Posted on 2020-09-01
4350 Polygenic mutations model the pleiotropic disease of Fanconi Anemia
Schlacher, K.; Tomaszowski, K.-H.; Roy, S.; Keshvani, C.; Ott, M.; DiNardo, C.; Schindler, D.
10.1101/2020.09.01.277038 — cancer biology — Posted on 2020-09-01
4351 Sex change in the New Zealand spotty wrasse (Notolabrus celidotus), a temperate model species
Goikoetxea, A.; Muncaster, S.; Todd, E. V.; Lokman, P. M.; Robertson, H.; Moraes, C.; Damsteegt, E. L.; Gemmell, N. J.
10.1101/2020.08.28.271973 — physiology — Posted on 2020-09-01