date is 2021-02
Select an archive month  
May 2025
April 2025
March 2025
February 2025
January 2025
December 2024
November 2024
October 2024
September 2024
August 2024
July 2024
June 2024
May 2024
April 2024
March 2024
February 2024
January 2024
December 2023
November 2023
October 2023
September 2023
August 2023
July 2023
June 2023
May 2023
April 2023
March 2023
February 2023
January 2023
December 2022
November 2022
October 2022
September 2022
August 2022
July 2022
June 2022
May 2022
April 2022
March 2022
February 2022
January 2022
December 2021
November 2021
October 2021
September 2021
August 2021
July 2021
June 2021
May 2021
April 2021
March 2021
February 2021
January 2021
December 2020
November 2020
October 2020
September 2020
August 2020
July 2020
June 2020
May 2020
April 2020
March 2020
February 2020
January 2020
December 2019
November 2019
October 2019
September 2019
August 2019
July 2019
June 2019
May 2019
April 2019
March 2019
February 2019
January 2019
December 2018
November 2018
October 2018
September 2018
August 2018
July 2018
June 2018
May 2018
April 2018
March 2018
February 2018
January 2018
December 2017
November 2017
October 2017
September 2017
August 2017
July 2017
June 2017
May 2017
April 2017
March 2017
February 2017
January 2017
December 2016
November 2016
October 2016
September 2016
August 2016
July 2016
June 2016
May 2016
April 2016
March 2016
February 2016
January 2016
December 2015
November 2015
October 2015
September 2015
August 2015
July 2015
June 2015
May 2015
April 2015
March 2015
February 2015
January 2015
December 2014
November 2014
October 2014
September 2014
August 2014
July 2014
June 2014
May 2014
April 2014
March 2014
February 2014
January 2014
December 2013
November 2013

Archive, 2021-02

2 Re-treatment with direct-acting antivirals policy is needed to eliminate Hepatitis C among persons who inject drugs
Tatara, E.; Gutfraind, A.; Collier, N. T.; Echevarria, D.; Cotler, S. J.; Major, M.; Ozik, J.; Dahari, H.; Boodram, B.
10.1101/653196 — epidemiology — Posted on 2021-02-22
3 Ownership, Coverage, Utilisation and Maintenance of Long-lasting insecticidal nets in Three Health Districts in Cameroon: A Cross-Sectional Study
Cho, F. N.; Fru, P. N.; Cho, B. M.; Munguh, S. F.; Jokwi, P. K.; Ngah, Y. E.; Fru, C. N.; Tassang, A. N.; Fon, P. N.; Ekobo, A. S.
10.1101/465005 — epidemiology — Posted on 2021-02-22
4 Destabilization of β-cell FIT2 by saturated fatty acids contribute to ER stress and diabetes
Zheng, X.; Ho, Q. W. C.; Chua, M.; Stelmashenko, O.; Muralidharan, S.; Torta, F. T.; Chew, E. G. Y.; Lian, M. M.; Foo, J. N.; Wenk, M. R.; Silver, D. L.; Berggren, P.-O.; Ali, Y.
10.1101/2021.02.28.433270 — biochemistry — Posted on 2021-02-28
6 Collagen polarization provides a structural memory for the elongation of epithelial anlage.
Katsuno-Kambe, H.; Teo, J. L.; Ju, R. J.; Hudson, J. E.; Stehbens, S. J.; Yap, A. S.
10.1101/2021.02.28.433274 — cell biology — Posted on 2021-02-28
8 Histone demethylome map reveals combinatorial gene regulatory functions in embryonic stem cells
Kumar, Y.; Tripathi, P.; Mehravar, M.; Zhang, Z.; Dakle, P.; Bullen, M. J.; Pandey, V. K.; Hathiwala, D.; Kerenyi, M.; Woo, A.; Ghamari, A.; Cantor, A. B.; Wong, L. H.; Kim, J.; Glass, K.; Yuan, G.-C.; Pinello, L.; Orkin, S. H.; Das, P. P.
10.1101/2020.08.27.269514 — genomics — Posted on 2021-02-28
11 Gut microbial structural variations as determinants of human bile acid metabolism
Wang, D.; Doestzada, M.; Chen, L.; Andreu-Sanchez, S.; van den Munckhof, I. C. L.; Augustijn, H.; Koehorst, M.; Bloks, V. W.; Riksen, N. P.; Rutten, J. H. W.; Netea, M. G.; Zhernakova, A.; Kuipers, F.; Fu, J.
10.1101/2021.02.28.432952 — microbiology — Posted on 2021-02-28
12 Somatosensory processing deficits and altered cortico-hippocampal connectivity in Shank3b-/- mice
Balasco, L.; Pagani, M.; Pangrazzi, L.; Schlosman, E.; Mattioni, L.; Galbusera, A.; Provenzano, G.; Gozzi, A.; Bozzi, Y.
10.1101/2021.02.28.433258 — neuroscience — Posted on 2021-02-28
13 Donor-derived vasculature is required to support neocortical cell grafts after stroke
Krzyspiak, J.; Yan, J.; Ghosh, H.; Galinski, B.; Lituma, P. J.; Alvina, K.; Washburn, S.; Gronska-Peski, M.; Tai, Y. D.; McDermott, K.; Zukin, S.; Weiser, D.; Castillo, P. E.; Khodakhah, K.; Hebert, J.
10.1101/2021.02.27.433204 — neuroscience — Posted on 2021-02-28
16 Protein Design and Variant Prediction Using Autoregressive Generative Models
Shin, J.-E.; Riesselman, A. J.; Kollasch, A. W.; McMahon, C.; Simon, E.; Sander, C.; Manglik, A.; Kruse, A. C.; Marks, D. S.
10.1101/757252 — systems biology — Posted on 2021-02-28
18 VPRBP functions downstream of the androgen receptor and OGT to restrict p53 activation in prostate cancer
Poulose, N.; Polonski, A.; Forsythe, N.; Gregg, G.; Maguire, S.; Fuchs, M.; Minner, S.; McDade, S. S.; Mills, I.
10.1101/2021.02.28.433236 — cancer biology — Posted on 2021-02-28
21 MASiVar: Multisite, Multiscanner, and Multisubject Acquisitions for Studying Variability in Diffusion Weighted Magnetic Resonance Imaging
Cai, L. Y.; Yang, Q.; Kanakaraj, P.; Nath, V.; Newton, A. T.; Edmonson, H. A.; Luci, J.; Conrad, B. N.; Price, G. R.; Hansen, C. B.; Kerley, C. I.; Ramadass, K.; Yeh, F.-C.; Kang, H.; Garyfallidis, E.; Descoteaux, M.; Rheault, F.; Schilling, K. G.; Landman, B. A.
10.1101/2020.12.03.408567 — bioengineering — Posted on 2021-02-28
22 HNF4α isoforms regulate the circadian balance between carbohydrate and lipid metabolism in the liver
Deans, J. R.; Deol, P.; Titova, N.; Radi, S. H.; Vuong, L. M.; Evans, J. R.; Pan, S.; Fahrmann, J.; Yang, J.; Hammock, B. D.; Fiehn, O.; Fekry, B.; Eckel-Mahan, K.; Sladek, F. M.
10.1101/2021.02.28.433261 — genomics — Posted on 2021-02-28
25 PDX1 directs a core developmentally and evolutionarily conserved gene program in the pancreatic islet
Yang, X.; Raum, J. C.; Kim, J.; Yu, R.; Yang, J.; Rice, G.; Li, C.; Won, K.-J.; Stoffers, D. A.; Stanescu, D. E.
10.1101/2021.02.28.433241 — developmental biology — Posted on 2021-02-28
29 Alanine cross-feeding determines Escherichia coli colony growth dynamics
Diaz-Pascual, F.; Lempp, M.; Nosho, K.; Jeckel, H.; Jo, J. K.; Neuhaus, K.; Hartmann, R.; Jelli, E.; Hansen, M. F.; Dietrich, L. E. P.; Link, H.; Drescher, K.
10.1101/2021.02.28.433255 — microbiology — Posted on 2021-02-28
37 Whole-genome doubling-aware copy number phylogenies for cancer evolution with MEDICC2
Petkovic, M.; Watkins, T. B.; Colliver, E. C.; Laskina, S.; Swanton, C.; Haase, K.; Schwarz, R. F.
10.1101/2021.02.28.433227 — bioinformatics — Posted on 2021-02-28
40 DLL4 and PDGF-BB regulate migration of human iPSC-derived skeletal myogenic progenitors
Ferrari, G.; Choi, S.; Moyle, L. A.; Mackinlay, K.; Naouar, N.; Wells, C.; Muntoni, F.; Tedesco, F. S.
10.1101/2021.02.28.431778 — cell biology — Posted on 2021-02-28
43 A unicellular walker embodies a finite state machine
Larson, B. T.; Garbus, J.; Pollack, J. B.; Marshall, W. F.
10.1101/2021.02.26.433123 — cell biology — Posted on 2021-02-28
44 The Epstein-Barr virus ubiquitin deconjugase BPLF1 regulates the activity of Topoisomerase II during virus replication
Li, J.; Nagy, N.; Liu, J.; Gupta, S.; Frisan, T.; Hennig, T.; Cameron, D. P.; Baranello, L.; Masucci, M. G.
10.1101/2021.02.26.433008 — microbiology — Posted on 2021-02-28
45 Sustained antibody response to ZIKV infection induced by NS1 protein is accompanied by the progressive appearance of autoreactive antibodies and cross-reactive B cell clones.
Cavazzoni, C. B.; Bozza, V. B.; Tostes, L.; Maia, B.; Mesin, L.; Schiepers, A.; Ersching, J.; Neris, R. L.; Conde, J. N.; Coleho, D. R.; Conde, L.; Paula-Neto, H. A.; Lima, T. M.; Alvim, R. G. F.; Castilho, L. R.; Mohana-Borges, R.; Assuncao-Miranda, I.; Nobrega, A.; Victora, G. D.; Vale, A. M.
10.1101/2020.12.24.423863 — immunology — Posted on 2021-02-28
47 Ultra-high field (7T) functional magnetic resonance imaging in amyotrophic lateral sclerosis: a pilot study
Barry, R.; Babu, S.; Anteraper, S.; Triantafyllou, C.; Keil, B.; Rowe, O.; Rangaprakash, D.; Paganoni, S.; Lawson, R.; Dheel, C.; Cernasov, P.; Rosen, B.; Ratai, E.-M.; Atassi, N.
10.1101/2020.12.02.408278 — neuroscience — Posted on 2021-02-28
49 MASiVar: Multisite, Multiscanner, and Multisubject Acquisitions for Studying Variability in Diffusion Weighted Magnetic Resonance Imaging
Cai, L. Y.; Yang, Q.; Kanakaraj, P.; Nath, V.; Newton, A. T.; Edmonson, H. A.; Luci, J.; Conrad, B. N.; Price, G. R.; Hansen, C. B.; Kerley, C. I.; Ramadass, K.; Yeh, F.-C.; Kang, H.; Garyfallidis, E.; Descoteaux, M.; Rheault, F.; Schilling, K. G.; Landman, B. A.
10.1101/2020.12.03.408567 — bioengineering — Posted on 2021-02-28
52 Allelic and Genotypic Frequencies of NAT2, CYP2E1 and AADAC genes in a cohort of Peruvian Tuberculosis Patients
Levano, K. S.; Jaramillo-Valverde, L.; Tarazona, D. D.; Sanchez, C.; Capristano, S.; Solari, L.; Mendoza-Ticona, A.; Soto, A.; Rojas, C.; Zegarra-Chapoñan, R.; Guio, H.
10.1101/2021.02.27.433209 — genetics — Posted on 2021-02-28
53 CRYPTOCHROME suppresses the circadian proteome and promotes protein homeostasis
Wong, D. C. S.; Seinkmane, E.; Stangherlin, A.; Zeng, A.; Rzechorzek, N. M.; Beale, A. D.; Day, J.; Reed, M.; Peak-Chew, S. Y.; Styles, C. T.; Edgar, R. S.; Putker, M.; O'Neill, J. S.
10.1101/2020.05.16.099556 — cell biology — Posted on 2021-02-28
56 Integration of phenomics and transcriptomics data to reveal drivers of inflammatory processes in the skin
Batra, R.; Garzorz-Stark, N.; Lauffer, F.; Jargosch, M.; Pilz, C.; Roenneberg, S.; Schaebitz, A.; Boehner, A.; Seiringer, P.; Thomas, J.; Fereydouni, B.; Kutkaite, G.; Menden, M.; Tsoi, L. C.; Gudjonsson, J. E.; Theis, F. F.; Biedermann, T.; Schmidt-Weber, C. B.; Mueller, N.; Eyerich, S.; Eyerich, K.
10.1101/2020.07.25.221309 — immunology — Posted on 2021-02-28
57 Circumpolar peoples and their languages: lexical and genomic data suggest ancient Chukotko-Kamchatkan-Nivkh and Yukaghir-Samoyedic connections
Starostin, G.; Altınısık, N. E.; Zhivlov, M.; Changmai, P.; Flegontova, O.; Spirin, S. A.; Zavgorodnii, A.; Flegontov, P.; Kassian, A. S.
10.1101/2021.02.27.433193 — genomics — Posted on 2021-02-28
58 A partially sex-reversed giant kelp sheds light into the mechanisms of sexual differentiation in a UV sexual system
Mueller, D.; Gachet, E.; Godfroy, O.; Gueno, J.; Cossard, G.; Kunert, M.; Peters, A. F.; Westermeier, R. H.; Boland, W.; Cock, J. M.; Lipinska, A.; Coelho, S. M.
10.1101/2021.02.28.433149 — evolutionary biology — Posted on 2021-02-28
59 Beyond taxonomic identification: integration of ecological responses to a soil bacterial 16S rRNA gene database.
Jones, B. A.; Goodall, T.; George, P. B. L.; Gweon, H. s.; Puissant, J.; Read, D.; Emmett, B.; Robinson, D.; Jones, D.; Griffiths, R.
10.1101/843847 — microbiology — Posted on 2021-02-28
61 Integration of phenomics and transcriptomics data to reveal drivers of inflammatory processes in the skin
Batra, R.; Garzorz-Stark, N.; Lauffer, F.; Jargosch, M.; Pilz, C.; Roenneberg, S.; Schaebitz, A.; Boehner, A.; Seiringer, P.; Thomas, J.; Fereydouni, B.; Tsoi, L. C.; Gudjonsson, J. E.; Theis, F. F.; Biedermann, T.; Schmidt-Weber, C. B.; Mueller, N.; Eyerich, S.; Eyerich, K.
10.1101/2020.07.25.221309 — immunology — Posted on 2021-02-28
62 Unraveling the role of MADS transcription factor complexes in apple tree dormancy using sequential DAP-seq
Falavigna, V. d. S.; Severing, E.; Lai, X.; Estevan, J.; Farrera, I.; Hugouvieux, V.; Revers, L. F.; Zubieta, C.; Coupland, G.; Costes, E.; Andres, F.
10.1101/2021.02.21.431301 — plant biology — Posted on 2021-02-28
63 A synthetic RNA-mediated evolution system in yeast
Jensen, E. D.; Laloux, M.; Lehka, B. J.; Pedersen, L. E.; Jakociunas, T.; Jensen, M. K.; Keasling, J. D.
10.1101/2021.02.27.433199 — bioengineering — Posted on 2021-02-28
64 A new murine Rpl5 (uL18) mutation provides a unique model of variably penetrant Diamond Blackfan Anemia
Yu, L.; Lemay, P.; Ludlow, A.; Guyot, M.-C.; Jones, M.; Mohamed, F. F.; Saroya, G.-A.; Panaretos, C.; Schneider, E.; Wang, Y.; Myers, G.; Khoriaty, R.; Li, Q.; Franceschi, R.; Engel, J. D.; Kaartinen, V.; Rothstein, T. L.; Justice, M. J.; Kibar, Z.; Singh, S. A.
10.1101/2021.02.27.430069 — developmental biology — Posted on 2021-02-28
65 Brazil Nut Effect Drives Pattern Formation in Early Mammalian Embryos
guo, z.; Yao, J.; Zheng, X.; Cao, J.; Guo, S.; Qin, D.; Gao, Z.; Tan, M.; Wang, B.; Meng, F.; Zhang, J.; Chang, Z.; Li, L.; Du, J.; Fan, Y.
10.1101/2021.02.26.433068 — developmental biology — Posted on 2021-02-28
66 Comprehensive Profiling of Plasma Exosomes Using Data Independent Acquisitions, New Tools for Aging Cohort Studies
Patel, S. K.; Bruderer, R.; Basisty, N.; Bons, J.; Desprez, P.-Y.; Neri, F.; Reiter, L.; Campisi, J.; Schilling, B.
10.1101/2021.02.27.433188 — cell biology — Posted on 2021-02-28
67 G9a and Sirtuin6 epigenetically modulate host cholesterol accumulation to facilitate mycobacterial survival
Prakhar, P.; Bhatt, B.; Mukherjee, T.; Lohia, G. K.; Kolthur-Seetharam, U.; Sundaresan, N. R.; Rajmani, R. S.; Balaji, K. N.
10.1101/2021.02.27.433201 — microbiology — Posted on 2021-02-28
68 Allelic and Genotypic Frequencies of NAT2, CYP2E1 and AADAC genes in a cohort of Peruvian Tuberculosis Patients
Levano, K. S.; Jaramillo-Valverde, L.; Tarazona, D. D.; Sanchez, C.; Capristano, S.; Solari, L.; Mendoza-Ticona, A.; Soto, A.; Rojas, C.; Zegarra-Chapoñan, R.; Guio, H.
10.1101/2021.02.27.433209 — genetics — Posted on 2021-02-28
69 The scaffold-dependent function of RIPK1 in dendritic cells promotes injury-induced colitis
Moriwaki, K.; Park, C.; Koyama, K.; Balaji, S.; Kita, K.; Yagi, R.; Komazawa-Sakon, S.; Asuka, T.; Nakano, H.; Kamada, Y.; Miyoshi, E.; Chan, F.
10.1101/2021.02.27.433202 — immunology — Posted on 2021-02-28
71 Small-molecule-mediated OGG1 inhibition attenuates pulmonary inflammation and lung fibrosis
Tanner, L.; Single, A. B.; Bonghir, R. K. V.; Oomen, R.; Wallner, O.; Helleday, T.; Kalderen, C.; Egesten, A.
10.1101/2021.02.27.433075 — pharmacology and toxicology — Posted on 2021-02-28
72 The Parastagonospora nodorum necrotrophic effector SnTox5 targets the wheat gene Snn5 and facilitates entry into the leaf mesophyll
Kariyawasam, G.; Richards,, J. K.; Wyatt, N. A.; Running, K. L. D.; Xu, S. S.; Liu, Z.; Borowicz, P.; Faris, J. D.; Friesen, T. L. L.
10.1101/2021.02.26.433117 — pathology — Posted on 2021-02-28
73 Identification and characterization of a G-quadruplex structure in the pre-core promoter region of hepatitis B virus
Meier-Stephenson, V.; Badmalia, M. D.; Mrozowich, T.; Lau, K. C.; Schultz, S. K.; Gemmill, D. L.; Osiowy, C.; van Marle, G.; Coffin, C. S.; Patel, T. R.
10.1101/2021.01.19.427307 — biophysics — Posted on 2021-02-27
75 A comprehensive fitness landscape model reveals the evolutionary history and future evolvability of eukaryotic cis-regulatory DNA sequences
Vaishnav, E. D.; de Boer, C. G.; Yassour, M.; Molinet, J.; Fan, L.; Adiconis, X.; Thompson, D. A.; Cubillos, F. A.; Levin, J. Z.; Regev, A.
10.1101/2021.02.17.430503 — genomics — Posted on 2021-02-27
78 Single-cell analysis identifies a key role for Hhip in murine coronal suture development
Holmes, G.; Gonzalez-Reiche, A. S.; Saturne, M.; Zhou, X.; Borges, A. C.; Shewale, B.; Zhang, B.; van Bakel, H.; Jabs, E. W.
10.1101/2021.02.27.433115 — developmental biology — Posted on 2021-02-27
79 A unicellular walker embodies a finite state machine
Larson, B. T.; Garbus, J.; Pollack, J. B.; Marshall, W. F.
10.1101/2021.02.26.433123 — cell biology — Posted on 2021-02-28
80 Bioorthogonal labeling of transmembrane proteins with non-canonical amino acids allows access to masked epitopes in live neurons
Bessa-Neto, D.; Kuhlemann, A.; Beliu, G.; Pecoraro, V.; Doose, S.; Retailleau, N.; Chevrier, N.; Perrais, D.; Sauer, M.; Choquet, D.
10.1101/2021.02.27.433189 — cell biology — Posted on 2021-02-28
81 Value Shapes Abstraction During Learning
Cortese, A.; Yamamoto, A.; Hashemzadeh, M.; Sepulveda, P.; Kawato, M.; De Martino, B.
10.1101/2020.10.29.361469 — neuroscience — Posted on 2021-02-27
84 A unicellular walker embodies a finite state machine
Larson, B. T.; Garbus, J.; Pollack, J. B.; Marshall, W. F.
10.1101/2021.02.26.433123 — cell biology — Posted on 2021-02-27
87 Discovering single nucleotide variants and indels from bulk and single-cell ATAC-seq
Massarat, A. R.; Sen, A.; Jaureguy, J.; Tyndale, S. T.; Fu, Y.; Erikson, G.; McVicker, G.
10.1101/2021.02.26.433126 — bioinformatics — Posted on 2021-02-27
88 Fiber density and matrix stiffness modulate distinct cell migration modes in a 3D stroma mimetic composite hydrogel
Hiraki, H. L.; Matera, D. L.; Wang, W. Y.; Zarouk, A. A.; Argento, A. E.; Buschhaus, J. M.; Humphries, B. A.; Luker, G. D.; Baker, B. M.
10.1101/2021.02.27.433190 — bioengineering — Posted on 2021-02-27
90 Murine norovirus capsid plasticity - Glycochenodeoxycholic acid stabilizes P domain dimers and triggers escape from antibody recognition
Creutznacher, R.; Maass, T.; Duelfer, J.; Feldmann, C.; Hartmann, V.; Knickmann, J.; Westermann, L. T.; Smith, T. J.; Uetrecht, C.; Mallagaray, A.; Peters, T.; Taube, S.
10.1101/2021.02.27.433148 — biochemistry — Posted on 2021-02-27
93 Circulating miRNAs associated with bone mineral density in healthy adult baboons.
Quillen, E. E.; Foster, J.; Sheldrake, A.; Stainback, M.; Bredbenner, T. L.
10.1101/2021.02.27.433170 — genomics — Posted on 2021-02-27
94 Chromatin and transcriptomic profiling uncover dysregulation of the Tip60 HAT/HDAC2 epigenomic landscape in the neurodegenerative brain
Beaver, M.; Karisetty, B. C.; Zhang, H.; Bhatnagar, A.; Armour, E.; Parmar, V.; Brown, R.; Xiang, M.; Elefant, F.
10.1101/2021.02.27.433179 — genomics — Posted on 2021-02-27
95 Flor yeasts rewire the central carbon metabolism during wine alcoholic fermentation
Peltier, E.; Vion, C.; Abou Saada, O.; Friedrich, A.; Schacherer, J.; Marullo, P.
10.1101/2021.02.27.433177 — genetics — Posted on 2021-02-27
96 A de novo paradigm for male infertility
Oud, M. S.; Smits, R. M.; Smith, H. E.; Mastrorosa, F. K.; Holt, G. S.; Houston, B. J.; de Vries, P. F.; Alobaidi, B. K.; Batty, L. E.; Ismail, H.; Greenwood, J.; Sheth, H.; Mikulasova, A.; Astuti, G.; Gilissen, C. S.; McEleny, K.; Turner, H.; Coxhead, J.; Cockell, S. J.; Braat, D.; Fleischer, K.; D'Hauwers, K.; Schaafsma, E.; GEMINI Consortium, ; Nagirnaja, L.; Conrad, D.; Friedrich, C.; Kliesch, S.; Aston, K. I.; Riera-Escamilla, A.; Krausz, C. G.; Gonzaga-Jauregui, C.; Santibanez-Koref, M.; Elliott, D.; Vissers, L.; Tüttelmann, F.; O'Bryan, M.; Ramos, L.; Xavier, M. J.; van der Heijden, G
10.1101/2021.02.27.433155 — genetics — Posted on 2021-02-27
97 Novel epitopes of human monoclonal antibodies targeting the influenza virus N1 neuraminidase
Kirkpatrick Roubidoux, E.; McMahon, M.; Carreno, J. M.; Capuano, C.; Jiang, K.; Simon, V.; van Bakel, H.; Wilson, P.; Krammer, F.
10.1101/2021.02.26.433142 — microbiology — Posted on 2021-02-27
99 Protection from lethal Clostridioides difficile infection via intraspecies competition for co-germinant
Leslie, J. L.; Jenior, M. L.; Vendrov, K. C.; Standke, A.; Barron, M. R.; O'Brien, T. J.; Unverdorben, L.; Thaprawat, P.; Bergin, I. L.; Schloss, P. D.; Young, V. B.
10.1101/2021.02.26.433146 — microbiology — Posted on 2021-02-27
101 Downsizing in plants - UV induces pronounced morphological changes in cucumber in the absence of stress
Qian, M.; Rosenqvist, E.; Prinsen, E.; Pescheck, F.; Flygare, A.-M.; Kalbina, I.; Jansen, M. A. K.; Strid, A.
10.1101/2021.02.27.432481 — plant biology — Posted on 2021-02-27
103 Representation learning applications in biological sequence analysis
Iuchi, H.; Matsutani, T.; Yamada, K.; Sumi, S.; Hosoda, S.; Zhao, S.; Fukunaga, T.; Hamada, M.
10.1101/2021.02.26.433129 — bioinformatics — Posted on 2021-02-27
104 Whole Genome and Exome Sequencing Reference Datasets from A Multi-center and Cross-platform Benchmark Study
Zhao, Y.; Fang, L. T.; Shen, T.-W.; Choudhari, S.; Talsania, K.; Chen, J.; Shetty, J.; Kriga, Y.; Tran, B.; Zhu, B.; Chen, Z.; Chen, W.; Wang, C.; Jaeger, E.; Meerzaman, D.; Lu, C.; Idler, K.; Zheng, Y.; Shi, L.; Petitjean, V.; Sultan, M.; Hung, T.; Peters, E.; Drabek, J.; Vojta, P.; Maestro, R.; Gasparotto, D.; Koks, S.; Reimann, E.; Scherer, A.; Nordlund, J.; Liljedahl, U.; Foox, J.; Mason, C.; Xiao, W.
10.1101/2021.02.27.433136 — bioinformatics — Posted on 2021-02-27
105 Bioptim, a Python framework for Musculoskeletal Optimal Control in Biomechanics
Michaud, B.; Bailly, F.; Charbonneau, E.; Ceglia, A.; Sanchez, L.; Begon, M.
10.1101/2021.02.27.432868 — bioengineering — Posted on 2021-02-27
108 Identification of theTMEM232 gene associated with atopic dermatitis through targeted capture sequencing
Zheng, J.; Wu, Y.-Y.; Fang, W.-L.; Cai, X.-Y.; Zhang, Z.-y.-o.; Yu, C.-X.; Zheng, X.; Xiao, F.-L.
10.1101/2021.02.25.432973 — genomics — Posted on 2021-02-27
109 Bioorthogonal labeling of transmembrane proteins with non-canonical amino acids allows access to masked epitopes in live neurons
Choquet, D.; Sauer, M.; Bessa-Neto, D.; Kuhlemann, A.; Beliu, G.; Pecoraro, V.; Retailleau, N.; Chevrier, N.; Perrais, D.; Doose, S.
10.1101/2021.02.27.433189 — cell biology — Posted on 2021-02-27
112 Functional cooperativity mediated by rationally selected combinations of human monoclonal antibodies targeting the henipavirus receptor binding protein
Doyle, M. P.; Kose, N.; Borisevich, V.; Binshtein, E.; Amaya, M.; Nagel, M.; Annand, E. J.; Armstrong, E.; Bombardi, R.; Dong, J.; Schey, K. L.; Broder, C. C.; Zeitlin, L.; Kuang, E.; Bornholdt, Z.; West, B.; Geisbert, T. W.; Cross, R. W.; Crowe, J. E.
10.1101/2021.02.17.431743 — immunology — Posted on 2021-02-27
114 Single-cell ATAC and RNA sequencing reveal pre-existing and persistent subpopulations of cells associated with relapse of prostate cancer
Taavitsainen, S.; Engedal, N.; Cao, S.; Handle, F.; Erickson, A.; Prekovic, S.; Wetterskog, D.; Tolonen, T.; Vuorinen, E. M.; Kiviaho, A.; Nätkin, R.; Häkkinen, T.; Devlies, W.; Henttinen, S.; Kaarijärvi, R.; Lahnalampi, M.; Kaljunen, H.; Nowakowska, K.; Syvälä, H.; Bläuer, M.; Cremaschi, P.; Claessens, F.; Visakorpi, T.; Tammela, T. L.; Murtola, T.; Granberg, K. J.; Lamb, A. D.; Ketola, K.; Mills, I. G.; Attard, G.; Wang, W.; Nykter, M.; Urbanucci, A.
10.1101/2021.02.09.430114 — cancer biology — Posted on 2021-02-27
116 Fast and sensitive taxonomic assignment to metagenomic contigs
Mirdita, M.; Steinegger, M.; Breitwieser, F.; Soeding, J.; Levy Karin, E.
10.1101/2020.11.27.401018 — bioinformatics — Posted on 2021-02-27
118 Simulating rhizodeposition patterns around growing and exuding root systems
Landl, M.; Haupenthal, A.; Leitner, D.; Kroener, E.; Vetterlein, D.; Bol, R.; Vereecken, H.; Vanderborght, J.; Schnepf, A.
10.1101/2021.02.25.432851 — plant biology — Posted on 2021-02-27
120 High-Throughput Sequencing of 5S-IGS rDNA in Fagus L. (Fagaceae) reveals complex evolutionary patterns and hybrid origin of modern species
Cardoni, S.; Piredda, R.; Denk, T.; Grimm, G. W.; Papageorgiou, A. C.; Schulze, E.-D.; Scoppola, A.; Shanjani, P. S.; Suyama, Y.; Tomaru, N.; Worth, J. R. P.; Simeone, M. C.
10.1101/2021.02.26.433057 — evolutionary biology — Posted on 2021-02-27
121 Comprehensive analysis of chemical and biological problems associated with browning agents used in aquatic studies
Scharnweber, K.; Peura, S.; Attermeyer, K.; Bertilsson, S.; Bolender, L.; Buck, M.; Einarsdottir, K.; Garcia, S. L.; Gollnisch, R.; Grasset, C.; Groeneveld, M.; Hawkes, J.; Lindstrom, E. S.; Manthey, C.; Overgaard, R.; Rengefors, K.; Nunez, V. S.; Tranvik, L. J.; Szekely, A. J.
10.1101/2021.02.26.433092 — ecology — Posted on 2021-02-27
123 Improved correspondence of fMRI visual field localizer data after macroanatomical alignment
Qubad, M.; Barnes-Scheufler, C. V.; Schaum, M.; Raspor, E.; Roesler, L.; Peters, B.; Goebel, R.; Reif, A.; Bittner, R. A.
10.1101/2021.02.26.433066 — neuroscience — Posted on 2021-02-27
126 Sequence-unrelated long noncoding RNAs converged to modulate the activity of conserved epigenetic machineries across kingdoms
Fonouni-Farde, C.; Christ, A.; Blein, T.; Ramirez-Prado, J. S.; Legascue, M. F.; Latrasse, D.; Moison, M.; Lucero, L.; Ferrero, L.; Gonzalez, D.; Benhamed, M.; Quadrana, L.; Crespi, M.; Ariel, F.
10.1101/2021.02.26.433017 — plant biology — Posted on 2021-02-27
135 Machine learning for cell classification and neighborhood analysis in glioma tissue
Solorzano, L.; Wik, L.; Olsson Bontell, T.; Wang, Y.; Klemm, A. H.; Öfverstedt, J.; Jakola, A. S.; Östman, A.; Wählby, C.
10.1101/2021.02.26.433051 — bioinformatics — Posted on 2021-02-27
138 Marked differences in local bone remodeling in response to different marrow stimulation techniques in a large animal
Zlotnick, H. M.; Locke, R. C.; Stoeckl, B. D.; Patel, J. M.; Gupta, S.; Browne, K. D.; Koh, J.; Carey, J. L.; Mauck, R.
10.1101/2021.02.26.433037 — bioengineering — Posted on 2021-02-27
141 Genomic analyses of the extinct Sardinian dhole (Cynotherium sardous) reaveal its evolutionary history
Ciucani, M. M.; Sinding, M.-H. S.; Jensen, J. K.; Smith, O.; Bartolini Lucentini, S.; Rosengren, E.; Rook, L.; Tuveri, C.; Arca, M.; Cappellini, E.; Galaverni, M.; Randi, E.; Guojie, C.; Zhang, G.; Sicheritz-Ponten, T.; Dalen, L.; Gilbert, M. T. P.; Gopalakrishnan, S.
10.1101/2021.02.26.432714 — genomics — Posted on 2021-02-27
147 Seasonal dynamics are the major driver of microbial diversity and composition in intensive freshwater aquaculture
Marmen, S.; Fadeev, E.; Al Ashhab, A.; Benet-Perelberg, A.; Naor, A.; Patil, H. J.; Cytryn, E.; Viner-Mozzini, D.; Sukenik, A.; Lalzar, M.; Sher, D.
10.1101/2021.02.26.433039 — ecology — Posted on 2021-02-27
148 Insights into biotic and abiotic modulation of ocean mesopelagic communities
rigonato, j.; Budinich, M.; Murillo, A. A.; Brandao, M. C.; Pierella Karlusich, J. J.; Soviadan, Y. D.; Gregory, A. C.; Endo, H.; Kokoszka, F.; Vik, D.; Henry, N.; Fremont, P.; Labadie, K.; Zayed, A. A.; Dimier, C.; Picheral, M.; Searson, S.; Poulain, J.; Kandels, S.; PESANT, S.; Karsenti, E.; Bork, P.; Bowler, C.; Chaffron, S.; de Vargas, C.; Eveillard, D.; Gehlen, M.; Iudicone, D.; Lombard, F.; Ogata, H.; Stemmann, L.; Sullivan, M. B.; Sunagawa, S.; Wincker, P.; Jaillon, O.
10.1101/2021.02.26.433055 — ecology — Posted on 2021-02-27
151 The Epstein-Barr virus ubiquitin deconjugase BPLF1 regulates the activity of Topoisomerase II during virus replication
Li, J.; Nagy, N.; Liu, J.; Gupta, S.; Frisan, T.; Hennig, T.; Cameron, D. P.; Baranello, L.; Masucci, M. G.
10.1101/2021.02.26.433008 — microbiology — Posted on 2021-02-27
152 Chronic wireless neural population recordings with common marmosets
Walker, J.; Pirschel, F.; Sundiang, M.; Niekrasz, M.; MacLean, J. N.; Hatsopoulos, N.
10.1101/2021.02.25.432889 — neuroscience — Posted on 2021-02-27
153 Alpha Event-related Desynchronization During Reward Processing in Schizophrenia
Marton, T. F.; Roach, B.; Holroyd, C. B.; Ford, J. M.; McQuaid, J.; Mathalon, D. H.; Fryer, S. L.
10.1101/2021.02.25.432936 — neuroscience — Posted on 2021-02-27
158 A Regression Framework for Brain Network Distance Metrics
Tomlinson, C. E.; Laurienti, P. J.; Lyday, R. G.; Simpson, S. L.
10.1101/2021.02.26.432910 — neuroscience — Posted on 2021-02-27
159 3D Neuronal Mitochondrial Morphology in Axons, Dendrites, and Somata of the Aging Mouse Hippocampus
Faitg, J.; Lacefield, C.; Davey, T.; White, K.; Laws, R.; Kosmidis, S.; Reeve, A. K.; Kandel, E.; Vincent, A. E.; Picard, M.
10.1101/2021.02.26.433056 — neuroscience — Posted on 2021-02-27
161 NiftyTorch: A Deep Learning framework for NeuroImaging
Subramanian, A.; Lan, H.; Govindarajan, S.; Viswanathan, L.; Choupan, J.; Sepehrband, F.
10.1101/2021.02.26.433116 — neuroscience — Posted on 2021-02-27
162 A fungal powdery mildew pathogen induces extensive local and marginal systemic changes in the Arabidopsis thaliana microbiota
Duran, P.; Reinstaedler, A.; Rajakrut, A. L.; Hashimoto, M.; Garrido-Oter, R.; Schulze-Lefert, P.; Panstruga, R.
10.1101/2021.02.26.432829 — plant biology — Posted on 2021-02-27
165 TRPV1 in arteries enables a rapid myogenic tone
Phan, T. X.; Ton, H. T.; Gulyas, H.; Porszasz, R.; Toth, A.; Russo, R.; Kay, M. W.; Sahibzada, N.; Ahern, G. P.
10.1101/2021.02.25.432719 — physiology — Posted on 2021-02-27
169 Multidimensional Single-Nuclei RNA-Seq Reconstruction of Adipose Tissue Reveals Adipocyte Plasticity Underlying Thermogenic Response
Biagi, C. A.; Cury, S. S.; Alves, C. P.; Rabhi, N.; Silva, W. A.; Farmer, S. R.; Carvalho, R. F.; Batista, M. L.
10.1101/2021.02.16.431320 — cell biology — Posted on 2021-02-27
170 Cell-to-cell heterogeneities during extrinsic apoptosis arise from cell cycle progression and transmitotic apoptosis resistance
Pollak, N.; Lindner, A.; Imig, D.; Kuritz, K.; Fritze, J. S.; Heinrich, I.; Stadager, J.; Eisler, S. A.; Stöhr, D.; Allgöwer, F.; Scheurich, P.; Morrison (Rehm), M.
10.1101/2021.02.26.433034 — cell biology — Posted on 2021-02-27
171 A Tad-like apparatus is required for contact-dependent prey killing in predatory social bacteria
Seef, S.; Herrou, J.; de Boissier, P.; My, L.; Brasseur, G.; Robert, D.; Jain, R.; Mercier, R.; Cascales, E.; Habermann, B. H.; Mignot, T.
10.1101/2021.02.25.432843 — microbiology — Posted on 2021-02-27
173 Analyses of the complete genome sequence of 2,6-dichlorobenzamide (BAM) degrader Aminobacter sp. MSH1 suggests a polyploid chromosome, phylogenetic reassignment, and functions of (un)stable plasmids.
Nielsen, T. K.; Horemans, B.; Lood, C.; T'Syen, J.; van Noort, V.; Lavigne, R.; Ellegaard-Jensen, L.; Hylling, O.; Aamand, J.; Springael, D.; Hansen, L. H.
10.1101/2021.02.25.432982 — microbiology — Posted on 2021-02-27
174 Gene flux and acid-imposed selection are the main drivers of antimicrobial resistance in broiler chicks infected with Salmonella enterica serovar Heidelberg
Oladeine, A.; Abdo, Z.; Press, M. O.; Cook, K.; Cox, N. A.; Zwirzitz, B.; Woyda, R.; Lakin, S. M.; Thomas, J. C.; Looft, T.; Cosby, D. E.; Hinton, A.; Guard, J.; Line, E.; Rothrock, M. J.; Berrang, M. E.; Herrington, K.; Zock, G.; Plumblee Lawrence, J.; Cudnik, D.; House, S.; Ingram, K.; Lariscy, L.; Wagner, M.; Aggrey, S. E.; Chai, L.; Ritz, C.
10.1101/2021.02.25.432983 — microbiology — Posted on 2021-02-27
175 A public broadly neutralizing antibody class targets a membrane-proximal anchor epitope of influenza virus hemagglutinin
Guthmiller, J. J.; Han, J.; Utset, H. A.; Li, L.; Lan, L. Y.-L.; Henry, C.; Stamper, C. T.; Stovicek, O.; Gentles, L.; Dugan, H. L.; Zheng, N.-Y.; Richey, S. T.; Tepora, M. E.; Bitar, D. J.; Changrob, S.; Strohmeier, S.; Huang, M.; Garcia-Sastre, A.; Nachbagauer, R.; Palese, P.; Bloom, J. D.; Krammer, F.; Coughlan, L.; Ward, A. B.; Wilson, P. C.
10.1101/2021.02.25.432905 — immunology — Posted on 2021-02-27
177 Dual targeting of salt inducible kinases and CSF1R uncouples bone formation and bone resorption
Tang, C.-C.; Castro, C.; O'Meara, M. J.; Yoon, S.-H.; Brooks, D. J.; Bouxsein, M. L.; Martins, J. d. S.; Wang, J.; Gray, N. S.; Misof, B.; Roschger, P.; Boulin, S.; Klaushofer, K.; Velduis-Vlug, A.; Vegting, Y.; Rosen, C. J.; O'Connell, D.; Sundberg, T. B.; Xavier, R. J.; Ung, P.; Schlessinger, A.; Kronenberg, H. M.; Berdeaux, R.; Foretz, M.; Wein, M. N.
10.1101/2021.02.26.433094 — physiology — Posted on 2021-02-27
178 Characterising ontogeny of numerosity discrimination in zebrafish reveals multiple, numerical and non- numerical mechanisms.
Sheardown, E.; Torres-Perez, J. V.; Anagianni, S.; Fraser, S.; Vallortigara, G.; Butterworth, B.; Miletto-Petrazzini, M. E.; Brennan, C. H.
10.1101/2021.02.25.432846 — animal behavior and cognition — Posted on 2021-02-27
179 AIM-CICs: automatic identification method for Cell-in-cell structures based on convolutional neural network
Tang, M.; Su, Y.; Zhao, W.; Niu, Z.; Ruan, B.; Li, Q.; Zheng, Y.; Wang, C.; Zhou, Y.; Zhang, B.; Zhou, F.; Huang, H.; Shi, H.; Sun, Q.
10.1101/2021.02.26.432996 — cell biology — Posted on 2021-02-27
180 Fiber-associated Lachnospiraceae reduce colon tumorigenesis by modulation of the tumor-immune microenvironment
Almeida, A. S.; Tran, T. T. T.; Ghosh, T. S.; Ribiere, C.; Foley, C.; Alves, L. A.; Pellanda, P.; Frei, W.; Hueston, C. M.; Kumar, R.; Flemer, B.; Sequeira, I.; O'Riordain, M.; Shanahan, F.; O'Toole, P. W.
10.1101/2021.02.24.432654 — microbiology — Posted on 2021-02-27
182 Extended numerical analysis of an eyeball injury under direct impact
Koberda, M.; Skorek, A.; Kłosowski, P.; Zmuda-Trzebiatowski, M.; Zerdzicki, K.; Lemski, P.; Stodolska-Koberda, U.
10.1101/2021.02.26.433021 — pathology — Posted on 2021-02-26
184 THz irradiation inhibits cell division by affecting actin dynamics
yamazaki, s.; Ueno, Y.; Hosoki, R.; Saito, T.; Idehara, T.; Yamaguchi, Y.; Otani, C.; Ogawa, Y.; Harata, M.; Hoshina, H.
10.1101/2021.02.26.433024 — cell biology — Posted on 2021-02-26
191 Biomechanical evaluation of a novel orthogonal angle-stable interlocking nail in a canine femur model
Lucena, D.; Farias, D. V. F.; Minto, B. W.; Rocha, T. A. S. S.; Malta, C. A. S.; Galindez, J. A. S.; Dias, L. G. G. G.
10.1101/2021.02.26.433020 — bioengineering — Posted on 2021-02-26
193 Parallel evolution of a splicing program controlling neuronal excitability in flies and mammals
Torres-Mendez, A.; Pop, S.; Bonnal, S.; Almudi, I.; Roberts, R. J. V.; Paolantoni, C.; Alcaina, A.; Avola, A.; Martin Anduaga, A.; Haussmann, I. H.; Morin, V.; Casares, F.; Soller, M.; Kadener, S.; Roignant, J.-Y.; Prieto-Godino, L.; Irimia, M.
10.1101/2021.02.24.432780 — molecular biology — Posted on 2021-02-26
195 An integrated comparative physiology and molecular approach pinpoints mediators of breath-hold capacity in dolphins
Blawas, A. M.; Ware, K. E.; Schmaltz, E.; Zheng, L.; Spruance, J.; Allen, A. S.; West, N.; Devos, N.; Corcoran, D. L.; Nowacek, D. P.; Eward, W. C.; Fahlman, A.; Somarelli, J. A.
10.1101/2021.01.20.425775 — physiology — Posted on 2021-02-26
196 Ovarian Tumor Mitochondria Exhibit Abnormal Phenotypes and Blunted Associations with Biobehavioral Factors
Bindra, S.; McGill, M. A.; Triplett, M. K.; Tyagi, A.; Thaker, P. H.; Dahmoush, L.; Goodheart, M. J.; Ogden, T.; Owusu-Ansah, E.; Karan, K.; Cole, S.; Sood, A. K.; Lutgendorf, S. K.; Picard, M.
10.1101/2021.02.26.432917 — cancer biology — Posted on 2021-02-26
200 X chromosome-dependent disruption of placental regulatory networks in hybrid dwarf hamsters
Brekke, T. D.; Moore, E. C.; Campbell-Staton, S. C.; Callahan, C. M.; Cheviron, Z. A.; Good, J. M.
10.1101/2020.09.15.298893 — evolutionary biology — Posted on 2021-02-26
202 PI3K Signaling Specifies Proximal-Distal Fate by Driving a Developmental Gene Regulatory Network in Sox9+ Lung Progenitors
Khattar, D.; Fernandes, S.; Snowball, J.; Guo, M.; Gillen, M. C.; Sinner, D. I.; Zacharias, W.; Swarr, D. T.
10.1101/2021.02.26.433053 — developmental biology — Posted on 2021-02-26
203 Asymmetric Contraction of Adherens Junctions arises through RhoA and E-cadherin feedback
Cavanaugh, K.; Staddon, M.; Chmiel, T. A.; Harmon, R. M.; Budnar, S.; Yap, A. S.; Banerjee, S.; Gardel, M.
10.1101/2021.02.26.433093 — cell biology — Posted on 2021-02-26
205 Completion of the gut microbial epi-bile acid pathway
Doden, H. L.; Alves, J. M. P.; Ridlon, J. M.; Wolf, P. G.; Gaskins, H. R.; Anantharaman, K.
10.1101/2020.09.27.315549 — microbiology — Posted on 2021-02-26
208 Oxytocin administration in neonates shapes the hippocampal circuitry and restores social behavior in a mouse model of autism.
Bertoni, A.; Schaller, F.; Tyzio, R.; Gaillard, S.; Santini, F.; Xolin, M.; Diabira, D.; Vaidyanathan, R.; Matarazzo, V.; Medina, I.; Hammock, E.; Zhang, J.; Chini, B.; Gaiarsa, J.-L.; Muscatelli, F.
10.1101/2020.09.21.306217 — neuroscience — Posted on 2021-02-26
209 Calbindin regulates Kv4.1 trafficking and excitability of dentate granule cells via CaMKII-dependent phosphorylation
Kim, K.-R.; Jeong, H.-J.; Kim, Y.; Lee, S. Y.; Kim, Y.; Kim, H.-J.; Lee, S.-H.; Cho, H.; Kim, J.-S.; Ho, W.-K.
10.1101/2021.02.26.433035 — neuroscience — Posted on 2021-02-26
210 Acyloxyacyl Hydrolase Regulates Microglia-Mediated Pelvic Pain Through Toll-Like Receptor-4
Rahman-Enyart, A.; Yaggie, R. E.; Yang, W.; Bollinger, J. L.; Winter, D. R.; Schaeffer, A. J.; Klumpp, D. J.
10.1101/2021.02.26.433087 — neuroscience — Posted on 2021-02-26
213 Cyclocreatine suppresses prostate tumorigenesis through dual effects on SAM and creatine metabolism
Patel, R.; Rodgers, L.; Ford, C. A.; Rushworth, L.; Fleming, J.; Mui, E.; Zhang, T.; Watson, D. G.; MacKay, G.; Sumpton, D.; Sansom, O. J.; Leung, H. Y.
10.1101/2021.02.26.432994 — cancer biology — Posted on 2021-02-26
214 Resolving the spatial and cellular architecture of lung adenocarcinoma by multi-region single-cell sequencing
Sinjab, A.; Han, G.; Treekitkarnmongkol, W.; Kobayashi, K.; Brennan, P.; Dang, M.; Hao, D.; Wang, R.; Dai, E.; Dejima, H.; Zhang, J.; Bogatenkova, E.; Sanchez-Espiridion, B.; Chang, K.; Little, D. R.; Bazzi, S.; Tran, L.; Krysan, K.; Behrens, C.; Duose, D.; Parra, E. R.; Raso, M. G.; Solis, L. M.; Fukuoka, J.; Zhang, J.; Sepesi, B.; Cascone, T.; Byers, L.; Gibbons, D. L.; Chen, J.; Moghaddam, S. J.; Ostrin, E. J.; Rosen, D. G.; Heymach, J. V.; Scheet, P.; Dubinett, S.; Fujimoto, J.; Wistuba, I. I.; Stevenson, C. S.; Spira, A. E.; Wang, L.; Kadara, H.
10.1101/2020.09.04.283739 — cancer biology — Posted on 2021-02-26
215 An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma
Zewdu, R.; Mehrabad, E. M.; Ingram, K.; Fang, P.; Gillis, K. L.; Camolotto, S. A.; Orstad, G.; Jones, A.; Mendoza, M. C.; Spike, B. T.; Snyder, E. L.
10.1101/2020.02.25.965004 — cancer biology — Posted on 2021-02-26
218 Bi-phasic dynamics of the mitochondrial DNA mutation m.3243A>G in blood: An unbiased, mutation level-dependent model implies positive selection in the germline.
Fleishmann, Z.; Pickett, S. J.; Franco, M.; Aidlen, D.; Khrapko, M.; Stein, D.; Markuzon, N.; Popadin, K.; Braverman, M.; Woods, D. C.; Tilly, J. L.; Turnbull, D.; Khrapko, K.
10.1101/2021.02.26.433045 — genomics — Posted on 2021-02-26
219 Global genetic heterogeneity in adaptive traits
Lopez-Arboleda, W. A.; Reinert, S.; Nordborg, M.; Korte, A.
10.1101/2021.02.26.433043 — evolutionary biology — Posted on 2021-02-26
222 Identification of Human CD4+ Sub-population of Resident Cardiac Fibroblasts Linked to Inflammation-Mediated Cardiac Fibrosis
Siamwala, J. H.; Pagano, F.; Dubielecka, P. M.; Zhao, A.; Chen, S.; Granston, H.; Rounds, S.; Gilbert, R. J.
10.1101/2021.02.26.433023 — cell biology — Posted on 2021-02-26
228 Organotypic endothelial adhesion molecules are key for Trypanosoma brucei tropism and virulence
De Niz, M.; Bras, D.; Pedro, M.; Nascimento, A. M.; Franco, C. A.; Figueiredo, L. M.
10.1101/2021.02.26.433042 — microbiology — Posted on 2021-02-26
230 DENGUE VIRUS ALTERS SIALIC ACID RESIDUES CONFIGURATION IN MACROPHAGES
Serrato-Salas, J.; Cruz Zazueta, I.; Montiel Hernandez, J. L.; Gonzalez Christen, J.
10.1101/2021.02.26.433067 — immunology — Posted on 2021-02-26
231 IL-10 driven memory T cell survival and Tfh differentiation promote HIV persistence
Pereira Ribeiro, S.; Aid, M.; Dupuy, F. P.; Ngai Chan, C.; Hultquist, J.; Deleage, C.; Moysi, E.; Kulpa, D. A.; Li, L.; Xu, X.; Tamilselvan, B.; Tomalka, J. A.; Nekorchuk, M.; Busman-Sahay, K.; Bordi, R.; Simoneau, C.; Goulet, J. P.; Marconi, V.; Routy, J. P.; Balderas, R.; Micci, L.; J Howell, B.; H Barouch, D.; Krogan, N. J.; Petrovas, C.; Paiardini, M.; Deeks, S.; Estes, J. D.; Gorman, D.; J Hazuda, D.; Sekaly, R.-P.
10.1101/2021.02.26.432955 — immunology — Posted on 2021-02-26
232 Xenogeneic Skin Transplantation Promotes Angiogenesis and Tissue Regeneration Through Vitamin D-Activated Trem2+ Macrophages
Henn, D.; Chen, K.; Fehlmann, T.; Sivaraj, D.; Maan, Z.; Bonham, C. A.; Barrera, J. A.; Mays, C. J.; Greco, A. H.; Moortgat Illouz, S. E.; Lin, J. Q.; Foster, D.; Padmanabhan, J.; Momeni, A.; Nguyen, D.; Wan, D. C.; Kneser, U.; Januszyk, M.; Keller, A.; Longaker, M. T.; Gurtner, G. C.
10.1101/2021.02.26.432991 — immunology — Posted on 2021-02-26
236 Generation of excitatory and inhibitory neurons from common progenitors via Notch signaling in the cerebellum
Zhang, T.; Liu, T.; Mora, N.; Guegan, J.; Bertrand, M.; Contreras, X.; Hansen, A.; Streicher, C.; Anderle, M.; Tiberi, L.; Hippenmeyer, S.; Hassan, B. A.
10.1101/2020.03.18.997205 — developmental biology — Posted on 2021-02-26
237 An anaphase surveillance mechanism prevents micronuclei formation from mitotic errors
Orr, B.; De Sousa, F.; Gomes, M.; Ferreira, L. T.; Figueiredo, A. C.; Maiato, H.
10.1101/2021.02.26.433009 — cell biology — Posted on 2021-02-26
238 Comparative infectivity and pathogenesis of emerging SARS-CoV-2 variants in Syrian hamsters
Abdelnabi, R.; Boudewijns, R.; Foo, C. S.-Y.; Seldeslachts, L.; Sanchez-Felipe, L.; Zhang, X.; Delang, L.; Maes, P.; Kaptein, S. J. F.; Weynand, B.; Vande Velde, G.; Neyts, J.; Dallmeier, K.
10.1101/2021.02.26.433062 — microbiology — Posted on 2021-02-26
240 Antibodies with potent and broad neutralizing activity against antigenically diverse and highly transmissible SARS-CoV-2 variants
Wang, L.; Zhou, T.; Zhang, Y.; Yang, E. S.; Schramm, C. A.; Shi, W.; Pegu, A.; Oloninyi, O. K.; Ransier, A.; Darko, S.; Narpala, S. R.; Hatcher, C.; Martinez, D. R.; Tsybovsky, Y.; Phung, E.; Abiona, O. M.; Cale, E. M.; Change, L. A.; Corbett, K. S.; DiPiazza, A. T.; Gordon, I. J.; Leung, K.; Liu, T.; Mason, R. D.; Nazzari, A.; Novik, L.; Olia, A. S.; Stephens, T.; Stringham, C. D.; Talana, C. A.; Teng, I.-T.; Wagner, D.; Widge, A. T.; Zhang, B.; Roederer, M.; Ledgerwood, J. E.; Ruckwardt, T. J.; Gaudinski, M. R.; Baric, R. S.; Graham, B. S.; McDermott, A. B.; Doueck, D. C.; Kwong, P. D.; Masc
10.1101/2021.02.25.432969 — immunology — Posted on 2021-02-26
243 Negative DNA supercoiling tunes protein-mediated looping
Yan, Y.; Xu, W.; Kumar, S.; Zhang, A.; Leng, F.; Dunlap, D.; Finzi, L.
10.1101/2021.02.25.432970 — biophysics — Posted on 2021-02-26
246 Targeted replacement of full-length CFTR in human airway stem cells by CRISPR/Cas9 for pan-mutation correction in the endogenous locus
Vaidyanathan, S.; Baik, R.; Chen, L.; Bravo, D. T.; Suarez, C. J.; Abazari, S. M.; Salahudeen, A. A.; Dudek, A. M.; Teran, C. A.; Davis, T. H.; Lee, C. M.; Bao, G.; Randell, S. H.; Artandi, S. E.; Wine, J. J.; Kuo, C. J.; Desai, T. J.; Nayak, J. V.; Sellers, Z. M.; Porteus, M.
10.1101/2021.02.26.432961 — bioengineering — Posted on 2021-02-26
247 H3K36 methylation and DNA-binding are critical for Ioc4 recruitment and Isw1b remodeller function
Li, J.; Bergmann, L.; Webb, K. M.; Gogol, M. M.; Voigt, P.; Liu, Y.; Liang, H.; Smolle, M. M.
10.1101/2021.02.26.432832 — biochemistry — Posted on 2021-02-26
249 Physiological and transcriptomic variability indicative of differences in key functions within a single coral colony
Drake, J.; Malik, A.; Popovits, Y.; Yosef, O.; Shamesh, E.; Stolarski, J.; Tchernov, D.; Sher, D.; Mass, T.
10.1101/2021.02.25.432919 — genomics — Posted on 2021-02-26
252 AIM-CICs: automatic identification method for Cell-in-cell structures based on convolutional neural network
Tang, M.; Su, Y.; Zhao, W.; Niu, Z.; Ruan, B.; Li, Q.; Zheng, Y.; Wang, C.; Zhou, Y.; Zhang, B.; Zhou, F.; Huang, H.; Shi, H.; Sun, Q.
10.1101/2021.02.26.432996 — cell biology — Posted on 2021-02-26
253 Kasugamycin is a novel chitinase 1 inhibitor with strong antifibrotic effects on pulmonary fibrosis
Lee, J.-H.; Lee, C.-M.; Kim, M.-O.; Park, J. W.; Kamle, S.; Akosman, B.; Herzog, E. L.; Elias, J. A.; Lee, C. G.
10.1101/2021.02.25.432796 — immunology — Posted on 2021-02-26
255 Human Astrocytes Exhibit Tumor Microenvironment-, Age-, and Sex-Related Transcriptomic Signatures
Krawczyk, M. C.; Haney, J. R.; Caneda, C.; Khankan, R. R.; Reyes, S. D.; Chang, J. W.; Morselli, M.; Vinters, H. V.; Wang, A. C.; Cobos, I.; Gandal, M. J.; Bergsneider, M.; Kim, W.; Liau, L. M.; Yong, W.; Jalali, A.; Deneen, B.; Grant, G. A.; Mathern, G. W.; Fallah, A.; Zhang, Y.
10.1101/2021.02.25.432948 — neuroscience — Posted on 2021-02-26
259 Efficient in vivo genome editing mediated by stem cells-derived extracellular vesicles carrying designer nucleases
Bobis-Wozowicz, S.; Kania, K.; Nit, K.; Blazowska, N.; Kmiotek-Wasylewska, K.; Paw, M.; Karnas, E.; Szyposzynska, A.; Tyszka-Czochara, M.; Woznicka, O.; Boruczkowski, D.; Mussolino, C.; Łabaj, P. P.; Schambach, A.; Madeja, Z.; Cathomen, T.; Zuba-Surma, E.
10.1101/2021.02.25.432823 — bioengineering — Posted on 2021-02-26
261 COVID-19 Disease Map, a computational knowledge repository of SARS-CoV-2 virus-host interaction mechanisms
Ostaszewski, M.; Niarakis, A.; Mazein, A.; Kuperstein, I.; Phair, R.; Orta-Resendiz, A.; Singh, V.; Aghamiri, S. S.; Acencio, M. L.; Glaab, E.; Ruepp, A.; Fobo, G.; Montrone, C.; Brauner, B.; Frishman, G.; Monraz Gomez, L. C.; Somers, J.; Hoch, M.; Gupta, S. K.; Scheel, J.; Borlinghaus, H.; Czauderna, T.; Schreiber, F.; Montagud, A.; Ponce de Leon, M.; Funahashi, A.; Hiki, Y.; Hiroi, N.; Yamada, T. G.; Drager, A.; Renz, A.; Naveez, M.; Bocskei, Z.; Messina, F.; Bornigen, D.; Fergusson, L.; Conti, M.; Rameil, M.; Nakonecnij, V.; Vanhoefer, J.; Schmiester, L.; Wang, M.; Ackerman, E. E.; Shoemake
10.1101/2020.10.26.356014 — systems biology — Posted on 2021-02-26
263 A systematic analysis of metabolic pathways in the human gut microbiota
Pascal Andreu, V.; Augustijn, H. E.; Chen, L.; Zhernakova, A.; Fu, J.; Fischbach, M. A.; Dodd, D.; Medema, M. H.
10.1101/2021.02.25.432841 — bioinformatics — Posted on 2021-02-26
265 Bone Mineral Density modelled as a Random Field: a Feasibility Study on Pelvic Bone
Henys, P.; Vorechovsky, M.; Kuchar, M.; Heinemann, A.; Kopal, J.; Ondruschka, B.; Hammer, N.
10.1101/2021.02.25.432881 — biophysics — Posted on 2021-02-26
267 Polygenic Scores for Cognitive Abilities and their Association with Different Aspects of General Intelligence - a Deep Phenotyping Approach
Genc, E.; Schlüter, C.; Fraenz, C.; Arning, L.; Metzen, D.; Nguyen, H. P.; Voelkle, M. C.; Streit, F.; Güntürkün, O.; Kumsta, R.; Ocklenburg, S.
10.1101/2020.06.03.131318 — genetics — Posted on 2021-02-26
269 Evolution of thermal physiology alters predicted species distributions under climate change
Wuitchik, S. J.; Mogensen, S.; Barry, T. N.; Paccard, A.; Jamniczky, H. A.; Barrett, R. D.; Rogers, S. M.
10.1101/2021.02.25.432865 — ecology — Posted on 2021-02-26
274 Commensal Microbiota Regulates Skin Barrier Function And Repair Via Signaling Through The Aryl Hydrocarbon Receptor
Uberoi, A.; Bartow-McKenney, C.; Zheng, Q.; Flowers, L.; Campbell, A.; Knight, S. A. B.; Chan, N.; Wei, M.; Lovins, V.; Bugayev, J.; Horwinski, J.; Bradley, C.; Meyer, J.; Crumrine, D.; Sutter, C. H.; Elias, P.; Mauldin, E.; Sutter, T. R.; Grice, E. A.
10.1101/2020.12.05.413096 — microbiology — Posted on 2021-02-26
279 Visual object categorization in infancy
Spriet, C.; Abassi, E.; Hochmann, J.-R.; Papeo, L.
10.1101/2021.02.25.432436 — neuroscience — Posted on 2021-02-26
280 Pathogenic tau accelerates aging-associated activation of transposable elements in the mouse central nervous system
Ramirez, P.; Sun, W.; Zuniga, G.; Ochoa Thomas, E.; DeVos, S.; Hyman, B.; Chiu, G.; Roy, E. R.; Cao, W.; Orr, M.; Buggia-Prevot, V.; Ray, W. J.; Frost, B.
10.1101/2021.02.25.432716 — neuroscience — Posted on 2021-02-26
284 A triple threat: the Parastagonospora nodorum SnTox267 effector exploits three distinct host genetic factors to cause disease in wheat
Richards, J. K.; Kariyawasam, Gayan, G.; Seneviratne, S.; Wyatt, N. A.; Xu, S. S.; Liu, Z.; Faris, J. D.; Friesen, T. L. L.
10.1101/2021.02.25.432871 — pathology — Posted on 2021-02-26
285 Scaling concepts in 'omics: nuclear lamin-B scales with tumor growth and predicts poor prognosis, whereas fibrosis can be pro-survival
Vashisth, M.; Discher, D.; Cho, S.; Irianto, J.; Xia, Y.; Wang, M.; Hayes, B.; Jafarpour, F.; Liu, A.; Wells, R. G.
10.1101/2021.02.25.432860 — cancer biology — Posted on 2021-02-26
287 Addressing the Embeddability Problem in Transition Rate Estimation
Goolsby, C.; Losey, J.; Xu, Y.; Düker, M.-C.; Getmansky Sherman, M.; Matteson, D.; Moradi, M.
10.1101/707919 — biophysics — Posted on 2021-02-26
292 Different underlying mechanisms for high and low arousal in probabilistic learning in humans
Ciria, L. F.; Suarez-Pinilla, M.; Williams, A. G.; Jagannathan, S. R.; Sanabria, D.; Bekinschtein, T. A.
10.1101/2021.02.26.431959 — neuroscience — Posted on 2021-02-26
298 The novel, recurrent mutation in the TOP2A gene results in the enhanced topoisomerase activity and transcription deregulation in glioblastoma
Gielniewski, B.; Poleszak, K.; Roura, A.-J.; Szadkowska, P.; Krol, S. K.; Guzik, R.; Wiechecka, P.; Maleszewska, M.; Kaza, B.; Marchel, A.; Czernicki, T.; Koziarski, A.; Zielinski, G.; Styk, A.; Kawecki, M.; Szczylik, C.; Czepko, R.; Banach, M.; Kaspera, W.; Szopa, W.; Bujko, M.; Czapski, B.; Zabek, M.; Izycka-Swieszewska, E.; Kloc, W.; Nauman, P.; Cieslewicz, J.; Wojtas, B.; Kaminska, B.
10.1101/2020.06.17.158477 — cancer biology — Posted on 2021-02-26
300 Addressing the Embeddability Problem in Transition Rate Estimation
Goolsby, C.; Losey, J.; Xu, Y.; Düker, M.-C.; Getmansky Sherman, M.; Matteson, D.; Moradi, M.
10.1101/707919 — biophysics — Posted on 2021-02-26
302 Causal approach to environmental risks of seabed mining
Kaikkonen, L.; Helle, I.; Kostamo, K.; Kuikka, S.; Nygard, H.; Törnroos, A.; Venesjärvi, R.; Uusitalo, L.
10.1101/2021.02.21.432138 — ecology — Posted on 2021-02-26
304 Exploring the interaction network of a synthetic gut bacterial community
Weiss, A. S.; Burrichter, A. G.; Chakravarthy Durai Raj, A.; von Strempel, A.; Meng, C.; Kleigrewe, K.; Münch, P. C.; Rössler, L.; Huber, C.; Eisenreich, W.; Jochum, L. M.; Göing, S.; Jung, K.; Sanchez, A.; Stecher, B.
10.1101/2021.02.25.432904 — microbiology — Posted on 2021-02-26
305 Improving stroke detection via Correlation Tensor MRI
Alves, R.; Henriques, R. N.; Kerkela, L.; Chavarrias, C.; Jespersen, S.; Shemesh, N.
10.1101/2021.02.20.432088 — neuroscience — Posted on 2021-02-26
306 Self-contained and modular structured illumination microscope
Van den Eynde, R.; Vandenberg, W.; Hugelier, S.; Bouwens, A.; Hofkens, J.; Müller, M.; Dedecker, P.
10.1101/2021.02.25.432746 — biophysics — Posted on 2021-02-25
307 Modulating the voltage sensor of a cardiac potassium channel shows antiarrhythmic effects
Lin, Y.; Grinter, S. Z.; Lu, Z.; Xu, X.; Wang, H. Z.; Liang, H.; Hou, P.; Gao, J.; Clausen, C.; Shi, J.; Zhao, W.; Ma, Z.; Liu, Y.; White, K. M.; Zhao, L.; Kang, P.-W.; Zhang, G.; Cohen, I. S.; Zou, X.; Cui, J.
10.1101/2021.02.25.432939 — biophysics — Posted on 2021-02-25
310 Misinformation, Perceptions Towards COVID-19 and Willingness to be Vaccinated: A Population-Based Survey in Yemen
Bitar, A. N.; Zawiah, M.; Al-Ashwal, F. Y.; Kubas, M.; Saeed, R. M.; Abduljabbar, R.; Jaber, A. A. S.; Sulaiman, S. A. S.; Khan, A. H.
10.1101/2021.02.25.432838 — scientific communication and education — Posted on 2021-02-25
311 Frequent PIK3CA mutations in eutopic endometrium of patients with ovarian clear cell carcinoma
Murakami, K.; Kanto, A.; Sakai, K.; Miyagawa, C.; Takaya, H.; Nakai, H.; Kotani, Y.; Nishio, K.; Matsumura, N.
10.1101/2021.02.25.432943 — cancer biology — Posted on 2021-02-25
313 Intrinsic Gating Behavior of Voltage-Gated Sodium Channels Predetermines Regulation by Auxiliary β-subunits
Brake, N.; Mancino, A. S.; Yan, Y.; Shimomura, T.; Silveira, H.; Kubo, Y.; Khadra, A.; Bowie, D.
10.1101/2021.02.25.432706 — biophysics — Posted on 2021-02-25
315 A simple and robust method for automating analysis of naïve and regenerating peripheral nerves
Wong, A. L.; Hricz, N.; Malapati, H.; von Guionneau, N.; Wong, M. J.; Harris, T.; Boudreau, M.; Cohen-Adad, J.; Tuffaha, S.
10.1101/2021.02.25.432836 — neuroscience — Posted on 2021-02-25
317 Pax3 induces neural circuit repair through a developmental program of directed axon outgrowth.
Jara, J. S.; Avci, H. X.; Kouremenou, J.; Doulazmi, M.; Bakouche, J.; Dubacq, C.; Goyenvalle, C.; Mariani, J.; Lohof, A. M.; Sherrard, R. M.
10.1101/2021.02.25.432898 — neuroscience — Posted on 2021-02-25
318 Stratified Random Sampling Methodology for Observing Community Mask Use within Indoor Settings: Results from Louisville, Kentucky during the COVID-19 Pandemic
KARIMI, S. M.; Salunkhe, S. S.; White, K. B.; Little, B. M.; McKinney, W. P. M.; Mitra, R. M.; Chen, Y. M.; Adkins, E. R.; Barclay, J. A.; Ezekekwu, E. M.; He, C. X.; Hurst, D. M.; Popescu, M. M. M.; Swinney, D. N.; Johnson, D. A.; Hollenbach, R. M.; Moyer, S. M.; DuPre, N. R.
10.1101/2021.02.25.432837 — scientific communication and education — Posted on 2021-02-25
322 Age-related dedifferentiation and hyperdifferentiation of perceptual and mnemonic representations
Deng, L.; Davis, S. W.; Monge, Z. A.; Wing, E. A.; Geib, B. R.; Raghunandan, A.; Cabeza, R.
10.1101/2020.06.15.151217 — neuroscience — Posted on 2021-02-25
323 Elucidation of Japanese pepper (Zanthoxylum piperitum De Candolle) domestication using RAD-Seq
Premarathne, M. D. G. P.; Fukutome, N.; Yamasaki, K.; Hayakawa, F.; Nagano, A. J.; Mizuno, H.; Ibaragi, N.; Nagano, Y.
10.1101/2020.12.29.424752 — plant biology — Posted on 2021-02-25
324 CINS: Cell Interaction Network inference from Single cell expression data
Yuan, Y.; Cosme, C.; Adams, T. S.; Schupp, J.; Sakamoto, K.; Xylourgidis, N.; Ruffalo, M.; Kaminski, N.; Bar-Joseph, Z.
10.1101/2021.02.22.432206 — bioinformatics — Posted on 2021-02-25
325 Agency rescues competition for credit assignment among predictive cues from adverse learning conditions
Kang, M.; Reverte, I.; Volz, S. G.; Kaufman, K.; Fevola, S.; Matarazzo, A.; Alhazmi, F. H.; Marquez, I.; Iordanova, M. D.; Esber, G. R.
10.1101/2021.02.24.432808 — animal behavior and cognition — Posted on 2021-02-25
327 A minimal rDNA array replicates early, delays genome replication, and uncouples anaphase entry from S phase completion
Kwan, E. X.; Alvino, G. M.; Lynch, K. L.; Levan, P. F.; Amemiya, H. M.; Wang, X. S.; Johnson, S. A.; Sanchez, J. C.; Miller, M. A.; Croy, M.; Lee, S.-b. B.; Naushab, M.; Cuperus, J.; Brewer, B. J.; Queitsch, C.; Raghuraman, M. K.
10.1101/2021.02.25.432950 — molecular biology — Posted on 2021-02-25
328 Exploring the interaction network of a synthetic gut bacterial community
Weiss, A. S.; Burrichter, A. G.; Chakravarthy Durai Raj, A.; von Strempel, A.; Meng, C.; Kleigrewe, K.; Muench, P. C.; Roessler, L.; Huber, C.; Eisenreich, W.; Jochum, L. M.; Goeing, S.; Jung, K.; Sanchez, A.; Stecher, B.
10.1101/2021.02.25.432904 — microbiology — Posted on 2021-02-25
329 The plant immune receptors NRG1.1 and ADR1 are calcium influx channels
Jacob, P. M.; Kim, N. H.; Wu, F.; El Kasmi, F. M.; Walton, W. G.; Furzer, O. J.; Lietzen, A. D.; Sunil, S.; Kempthorn, K.; Redinbo, M.; Pei, Z.-M.; Wan, L.; Dangl, J. L.
10.1101/2021.02.25.431980 — plant biology — Posted on 2021-02-25
330 FrustratometeR: an R-package to compute Local frustration in protein structures, point mutants and MD simulations
Rausch, A. O.; Freiberger, M. I.; Leonetti, C. O.; Luna, D. M.; Radusky, L. G.; Wolynes, P. G.; Ferreiro, D. U.; Parra, R. G.
10.1101/2020.11.26.400432 — bioinformatics — Posted on 2021-02-25
333 The cis-regulatory effects of modern human-specific variants
Weiss, C. V.; Harshman, L.; Inoue, F.; Fraser, H. B.; Petrov, D. A.; Ahituv, N.; Gokhman, D.
10.1101/2020.10.07.330761 — evolutionary biology — Posted on 2021-02-25
335 Mechanically Sensitive HSF1 is a Key Regulator of Left-Right Symmetry Breaking in Zebrafish Embryos
Du, j.; Li, S. K.; Guan, L.-Y.; Guo, Z.; Yin, J.-F.; Gao, L.; Kawanishi, T.; Shimada, A.; Zhang, Q.-p.; Zheng, L.-S.; Liu, Y.-Y.; Feng, X.-X.; Chen, D.-Y.; Takeda, H.; Fan, Y.
10.1101/2021.02.25.432863 — developmental biology — Posted on 2021-02-25
336 The type 2 asthma mediator IL-13 inhibits SARS-CoV-2 infection of bronchial epithelium
Bonser, L. R.; Eckalbar, W. L.; Rodriguez, L.; Shen, J.; Koh, K. D.; Zlock, L. T.; Christenson, S.; Woodruff, P. G.; Finkbeiner, W. E.; Erle, D. J.
10.1101/2021.02.25.432762 — cell biology — Posted on 2021-02-25
337 Pyroptosis of syncytia formed by fusion of SARS-CoV-2 Spike and ACE2 expressing cells
Ma, H.; Zhu, Z.; Lin, H.; Wang, S.; Zhang, P.; Li, Y.; Li, L.; Wang, J.; Zhao, Y.; Han, J.
10.1101/2021.02.25.432853 — cell biology — Posted on 2021-02-25
338 ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation
van der Weegen, Y.; de Lint, K.; van den Heuvel, D.; Nakazawa, Y.; Narayanan, I. V.; Klaassen, N. H. M.; Wondergem, A. P.; Roohollahi, K.; van Schie, J. J. M.; Hara, Y.; Ljungman, M.; Ogi, T.; Wolthuis, R. M. F.; Luijsterburg, M. S.
10.1101/2021.02.25.432427 — molecular biology — Posted on 2021-02-25
339 A microRNA program controls the transition of cardiomyocyte hyperplasia to hypertrophy and stimulates mammalian cardiac regeneration
Raso, A.; Dirkx, E.; Sampaio-Pinto, V.; el Azzouzi, H.; Cubero, R. J.; Sorensen, D.; Ottaviani, L.; Olieslagers, S.; Huibers, M.; de Weger, R.; Siddiqi, S.; Moimas, S.; Torrrini, C.; Zentillin, L.; Braga, L.; da Costa Martins, P. A.; van Berlo, J. H.; Zaccigna, S.; Giacca, M.; De Windt, L. J.
10.1101/2021.02.25.432908 — molecular biology — Posted on 2021-02-25
341 MtrA regulation of essential peptidoglycan cleavage in Mycobacterium tuberculosis during infection
Peterson, E. J. R.; Brooks, A. N.; Reiss, D. J.; Kaur, A.; Wu, W.-J.; Morrison, R.; Srinivas, V.; Turkarslan, S.; Pan, M.; Carter, W.; Arrieta-Ortiz, M. L.; Ruiz, R. A.; Bhatt, A.; Baliga, N. S.
10.1101/2021.02.25.432019 — systems biology — Posted on 2021-02-25
342 Low nitrogen availability inhibits the phosphorus starvation response in maize (Zea mays ssp. mays L.)
Torres-Rodriguez, J. V.; Salazar-Vidal, M. N.; Chavez Montes, R. A.; Massange-Sanchez, J. A.; Gillmor, C. S.; Sawers, R. J. H.
10.1101/2020.10.29.360487 — plant biology — Posted on 2021-02-25
343 The immunosuppression of macrophages underlies the cardioprotective effects of catestatin (CST)
Ying, W.; Tang, K.; Avolio, E.; Schilling, J. M.; Pasqua, T.; Liu, M. A.; Cheng, H.; Gao, H.; Zhang, J.; Mahata, S.; Ko, M. S.; Bandyopadhyay, G. K.; Das, S.; Roth, D. M.; Sahoo, D.; Webster, N. J.; Sheikh, F.; Ghosh, G.; Patel, H. H.; Ghosh, P.; Bogaart, G. v. d.; Mahata, S. K.
10.1101/2020.05.12.092254 — physiology — Posted on 2021-02-25
344 Systems biology analysis identifies TCF7L1 as a key regulator of metastasis in Ewing sarcoma
Cidre-Aranaz, F.; Li, J.; Hoelting, T. L. B.; Orth, M. F.; Imle, R.; Kutschmann, S.; Ammirati, G.; Ceranski, K.; Carreno-Gonzalez, M. J.; Kasan, M.; Marchetto, A.; Funk, C. M.; Bestvater, F.; Bersini, S.; Arrigoni, C.; Moretti, M.; Romero-Perez, L.; Banito, A.; Ohmura, S.; Musa, J.; Kirchner, T.; Knott, M. M. L.; Gruenewald, T. G. P.
10.1101/2021.02.25.432862 — cancer biology — Posted on 2021-02-25
345 The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma.
Pan, M.; Wright, C.; Chapple, R.; Zubair, A.; Sandhu, M.; Batchelder, J.; Low, J.; Blankenship, K.; Wang, L.; Gordon, B.; Archer, P.; Brady, S. W.; Natarajan, S.; Pozsgai, M.; Schuetz, J.; Miller, D.; Kalathur, R.; chen, s.; Connelly, P.; Babu, M.; Dyer, M. A.; Pruett-Miller, S. M.; Freeman, B.; Chen, T.; Godley, L.; Blanchard, S.; Stewart, E.; Easton, J.; Geeleher, P.
10.1101/2021.02.25.432934 — cancer biology — Posted on 2021-02-25
346 ARYL HYDROCARBON RECEPTOR BLOCKS AGING-INDUCED SENESCENCE IN THE LIVER AND FIBROBLAST CELLS
Nacarino Palma, A.; Rico Leo, E. M.; Campisi, J.; Ramanathan, A.; Merino, J. M.; Fernandez-Salguero, P. M.
10.1101/2021.02.25.432074 — cancer biology — Posted on 2021-02-25
347 Chronos: a CRISPR cell population dynamics model
Dempster, J. M.; Boyle, I.; Vazquez, F.; Root, D. E.; Boehm, J. S.; Hahn, W. C.; Tsherniak, A.; McFarland, J.
10.1101/2021.02.25.432728 — bioinformatics — Posted on 2021-02-25
348 Polyvalent Guide RNAs for CRISPR Antivirals
Bagchi, R.; Tinker-Kulberg, R.; Supakar, T.; Chamberlain, S.; Ligaba-Osena, A.; Josephs, E. A.
10.1101/2021.02.25.430352 — bioengineering — Posted on 2021-02-25
351 A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2
Delorey, T. M.; Ziegler, C. G. K.; Heimberg, G.; Normand, R.; Yang, Y.; Segerstolpe, A.; Abbondanza, D.; Fleming, S. J.; Subramanian, A.; Montoro, D. T.; Jagadeesh, K. A.; Dey, K.; Sen, P.; Slyper, M.; Pita-Juarez, Y.; Phillips, D.; Bloom-Ackermann, Z.; Barkas, N.; Ganna, A.; Gomez, J.; Normandin, E.; Naderi, P.; Popov, Y. V.; Raju, S. S.; Niezen, S.; Tsai, L. T.- Y.; Siddle, K. J.; Sud, M.; Tran, V. M.; Karuthedath Vellarikkal, S.; Amir-Zilberstein, L.; Atri, D. S.; Beechem, J. M.; Brook, O. R.; Chen, J.; Divakar, P.; Dorceus, P.; Engreitz, J. M.; Essene, A.; Fitzgerald, D. M.; Fropf, R.; Gaz
10.1101/2021.02.25.430130 — genomics — Posted on 2021-02-25
355 The CCL2 Chemokine Promotes Early Seeding of the Latent HIV Reservoir
Packard, T.; Schwarzer, R.; Herzig, E.; Rao, D.; Luo, X.; Egedal, J.; Hsiao, F.; Widera, M.; Hultquist, J. F.; Grimmett, Z. W.; Messer, R. J.; Krogan, N. J.; Deeks, S.; Roan, N. R.; Dittmer, U.; Hasenkrug, K. J.; Greene, W. C.
10.1101/2021.02.25.432826 — cell biology — Posted on 2021-02-25
360 Comparison of the pathogenicity and virus shedding of SARS CoV-2 VOC 202012/01 and D614G variant in hamster model
Mohandas, S.; Yadav, P. D.; Nyayanit, D.; Deshpande, G.; Aich, A. S.; Sapkal, G.; Kumar, S.; Jain, R.; Kadam, M.; Kumar, A.; Patil, D. Y.; Sarkale, P.; Gawande, P.; Abraham, P.
10.1101/2021.02.25.432136 — microbiology — Posted on 2021-02-25
362 Proanthocyanidin-enriched cranberry extract induces resilient bacterial community dynamics in a gnotobiotic mouse model
Neto, C. C.; Mortzfeld, B. M.; Turbitt, J. R.; Bhattarai, S. K.; Yeliseyev, V.; DiBenedetto, N.; Bry, L. M.; Bucci, V.
10.1101/2021.02.25.432903 — microbiology — Posted on 2021-02-25
364 Human breast milk enhances intestinal mucosal barrier function and innate immunity in a pediatric human enteroid model
Noel, G.; In, J.; Lemme-Dumit, J. M.; DeVine, L. R.; Cole, R. N.; Guerrerio, A. L.; Kovbasnjuk, O.; Pasetti, M. F.
10.1101/2021.02.17.431653 — immunology — Posted on 2021-02-25
365 Tissue-resident, extravascular CD64-Ly6C- population forms a critical barrier for inflammation in the synovium
Montgomery, A. B.; Chen, S.-Y.; Gadhvi, G.; Mayr, M. G.; Cuda, C. M.; Dominguez, S.; Makinde, H. M.; Misharin, A.; Gurra, M. G.; AKBARPOUR, M.; Bharat, A.; Bundinger, G. R. S.; Winter, D. R.; Perlman, H.
10.1101/2021.02.25.432850 — immunology — Posted on 2021-02-25
377 Local Accumulation of Axonal Mitochondria in the Optic Nerve Glial Lamina Precedes Myelination
Wilkison, S. J.; Bright, C. L.; Vancini, R.; Song, D. J.; Bomze, H. M.; Cartoni, R.
10.1101/2021.02.25.432924 — neuroscience — Posted on 2021-02-25
378 Brain Morphometry and Diminished Physical Growth in Bangladeshi Children Growing up in Extreme Poverty: a Longitudinal Study
Turesky, T. K.; Shama, T.; Kakon, S. H.; Haque, R.; Someshwar, A.; Islam, N.; Petri, W.; Nelson, C. A.; Gaab, N.
10.1101/2021.02.24.432797 — neuroscience — Posted on 2021-02-25
379 Odor Blocking Of Stress
Lee, E. J.; Saraiva, L. R.; Hanchate, N. K.; Ye, X.; Asher, G.; Ho, J.; Buck, L. B.
10.1101/2021.02.24.432809 — neuroscience — Posted on 2021-02-25
383 Agency rescues competition for credit assignment among predictive cues from adverse learning conditions
Kang, M.; Reverte, I.; Volz, S. G.; Kaufman, K.; Fevola, S.; Matarazzo, A.; Alhazmi, F. H.; Marquez, I.; Iordanova, M. D.; Esber, G. R.
10.1101/2021.02.24.432808 — animal behavior and cognition — Posted on 2021-02-25
389 ExOrthist: a tool to infer exon orthologies at any evolutionary distance
Marquez, Y.; Mantica, F.; Cozzuto, L.; Burguera, D.; Hermoso-Pulido, A.; Ponomarenko, J.; Roy, S. W.; Irimia, M.
10.1101/2021.02.22.432358 — genomics — Posted on 2021-02-25
390 Genetic variation in haemoglobin regulates breathing in high-altitude deer mice
Ivy, C. M.; Wearing, O.; Natarajan, C.; Schweizer, R. M.; Gutierrez-Pinto, N.; Velotta, J. P.; Campbell-Staton, S. C.; Petersen, E. E.; Fago, A.; Cheviron, Z. A.; Storz, J. F.; Scott, G. R.
10.1101/2021.02.23.432531 — evolutionary biology — Posted on 2021-02-25
391 The Functional Significance of Bacterial Predators
Hungate, B. A.; Marks, J. C.; Power, M. E.; Schwartz, E.; van Groenigen, K. J.; Blazewicz, S. J.; Chuckran, P. F.; Dijkstra, P.; Finley, B. K.; Firestone, M. K.; Foley, M. M.; Greenlon, A.; Hayer, M.; Hofmockel, K.; Koch, B. J.; Mack, M. C.; Mau, R. L.; Miller, S. N.; Morrissey, E. M.; Propster, J. R.; Purcell, A. M.; Sieradzki, E. T.; Starr, E. P.; Stone, B. W. G.; Terrer, C.; Pett-Ridge, J.
10.1101/2021.02.22.432408 — ecology — Posted on 2021-02-25
392 Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism
Concha, M.; Pulgar, E.; Schwayer, C.; Guerrero, N.; Lopez, L.; Marquez, S.; Härtel, S.; Soto, R.; Heisenberg, C.-P.
10.1101/2021.02.24.432660 — developmental biology — Posted on 2021-02-25
393 Miltefosine enhances infectivity of miltefosine-resistant Leishmania infantum by attenuating innate immune recognition
Bulte, D.; Van Bockstal, L.; Dirkx, L. W.; Van den Kerkhof, M.; De Trez, C.; Timmermans, J.-P.; Hendrickx, S.; Maes, L.; Caljon, G.
10.1101/2021.02.22.432409 — microbiology — Posted on 2021-02-25
394 Cervical Squamous Intraepithelial Lesions are Associated with Changes in the Vaginal Microbiota of Mexican Women
Nieves-Ramirez, M.; Partida-Rodriguez, O.; Moran-Silva, P.; Serrano-Vazquez, A.; Perez-Juarez, H.; Perez-Rodriguez, M. E.; Arrieta, M. C.; Ximenez-Garcia, C.; Finlay, B. B.
10.1101/2021.02.23.432613 — microbiology — Posted on 2021-02-25
396 Bacterial Cytological Profiling Identifies Rhodanine-containing PAINS Analogs as Specific Inhibitors of E. coli Thymidylate Kinase in Vivo
Montano, E. T.; Nideffer, J. F.; Sugie, J.; Enustun, E.; Shapiro, A. B.; Tsunemoto, H.; Derman, A.; Pogliano, K.; Pogliano, J.
10.1101/2021.02.22.432404 — microbiology — Posted on 2021-02-25
398 Can we harness digital technologies and physiology to hasten genetic gain in U.S. maize breeding?
Diepenbrock, C. H.; Tang, T.; Jines, M.; Technow, F.; Lira, S.; Podlich, D.; Cooper, M.; Messina, C. D.
10.1101/2021.02.23.432477 — plant biology — Posted on 2021-02-25
399 High Affinity Chimeric Antigen Receptor with Cross-Reactive scFv to Clinically Relevant EGFR Oncogenic Isoforms
Thokala, R.; Binder, Z. A.; Yin, Y.; Zhang, L.; Zhang, J. V.; Zhang, D. Y.; Milone, M. C.; Ming, G.-L.; Song, H.; O'Rourke, D. M.
10.1101/2021.02.04.429797 — cancer biology — Posted on 2021-02-25
400 macroH2A2 shapes chromatin accessibility at enhancer elements in glioblastoma to modulate a targetable self-renewal epigenetic network
Nikolic, A.; Bobyn, A.; Maule, F.; Ellestad, K.; Lun, X.; Johnston, M.; Gafuik, C.; Zemp, F.; Paik, S.; Ninkovic, N.; Marhon, S.; Mehdipour, P.; Shen, Y.; Berger, D.; Brownsey, D.; Dirks, P.; Derksen, D.; Jones, S.; de Carvalho, D.; Senger, D.; Chan, J.; Mahoney, D.; Gallo, M.
10.1101/2021.02.23.432465 — cancer biology — Posted on 2021-02-25
403 Repulsive electrostatic interactions modulate dense and dilute phase properties of biomolecular condensates
Crabtree, M. D.; Holland, J.; Kompella, P. S.; Babl, L.; Turner, N. N.; Baldwin, A. J.; Nott, T. J.
10.1101/2020.10.29.357863 — cell biology — Posted on 2021-02-25
404 Longitudinal high-resolution imaging through a flexible intravital imaging window
Jacquemin, G.; Benavente-Diaz, M.; Djaber, S.; Bore, A.; Dangles-Marie, V.; Surdez, D.; Tajbakhsh, S.; Fre, S.; Lloyd-Lewis, B.
10.1101/2021.02.24.432491 — cell biology — Posted on 2021-02-25
405 Hippocampal sharp wave-ripples and the associated sequence replay emerge from structured synaptic interactions in a network model of area CA3
Ecker, A.; Bagi, B.; Vertes, E.; Steinbach-Nemeth, O.; Karlocai, M. R.; Papp, O. I.; Miklos, I.; Hajos, N.; Freund, T. F.; Gulyas, A. I.; Kali, S.
10.1101/2021.02.18.431868 — neuroscience — Posted on 2021-02-25
412 Towards a systematic characterization of protein complex function: a natural language processing and machine-learning framework
Sharma, V. S.; Fossati, A.; Ciuffa, R.; Buljan, M.; Williams, E. G.; Chen, Z.; Shao, W.; Pedrioli, P. G. A.; Purcell, A. W.; Rodriguez Martinez, M.; Song, J.; Manica, M.; Aebersold, R.; Li, C.
10.1101/2021.02.24.432789 — bioinformatics — Posted on 2021-02-25
417 Genetic and epigenetic determinants of reactivation of Mecp2 and the inactive X chromosome in neural stem cells.
Mira-Bontenbal, H.; Tan, B.; Gontan, C.; Goossens, S.; Boers, R. G.; Boers, J. B.; Dupont, C.; van Royen, M. E.; van IJcken, W.; French, P.; Bedalov, A.; Gribnau, J. M.
10.1101/2021.02.25.432827 — molecular biology — Posted on 2021-02-25
418 Parallel evolution of a splicing program controlling neuronal excitability in flies and mammals
Torres-Mendez, A.; Pop, S.; Bonnal, S.; Almudi, I.; Roberts, R. J. V.; Paolantoni, C.; Alcaina, A.; Avola, A.; Martin Anduaga, A.; Haussmann, I. H.; Morin, V.; Soller, M.; Kadener, S.; Roignant, J.-Y.; Prieto-Godino, L.; Irimia, M.
10.1101/2021.02.24.432780 — molecular biology — Posted on 2021-02-25
420 NADPH Oxidase 2 Derived Reactive Oxygen Species Promote CD8+ T cell Effector Function
Chen, J.; Liu, C.; Chernatynskaya, A.; Newby, B. N.; Brusko, T. M.; Xu, X.; Morgan, N.; Santarlas, C. P.; Reeves, W. H.; Tse, H. M.; Leiding, J. W.; Mathews, C. E.
10.1101/2021.02.24.432756 — immunology — Posted on 2021-02-25
421 Binocular vs. monocular recovery experience differentially promote recovery from visual deficits in a mouse model of amblyopia
Martinez, J. D.; Donnelly, M. J.; Popke, D.; Torres, D.; Sheskey, S.; Clawson, B. C.; Jiang, S.; Aton, S.
10.1101/2021.02.24.432698 — neuroscience — Posted on 2021-02-25
427 Progranulin promotes immune evasion of pancreatic adenocarcinoma through regulation of MHCI expression
Cheung, P. F.; Yang, J.; Krengel, K.; Althoff, K.; Yip, C.; Siu, E. H.; Ng, L. W.; Lang, K. S.; Cham, L.; Engel, D. R.; Soun, C.; Cima, I.; Scheffler, B.; Striefler, J. K.; Sinn, M.; Bahra, M.; Pelzer, U.; Oettle, H.; Markus, P.; Smeets, E. M.; Aarntzen, E. H.; Savvatakis, K.; Liffers, S.-T.; Neander, C.; Bazarna, A.; Zhang, X.; Paschen, A.; Crawford, H. C.; Chan, A. W.; Cheung, S. T.; Siveke, J. T.
10.1101/2021.02.24.432700 — cancer biology — Posted on 2021-02-25
428 Cancer cell-specific MHCII expression as a determinant of the immune infiltrate organization and function in the non-small cell lung cancer tumor microenvironment
Johnson, A. M.; Boland, J. M.; Wrobel, J. L.; Klezcko, E. K.; Weisner-Evans, M. L.; Heasley, L.; Clambey, E. T.; Nemenoff, R. L.; Schenk, E. L.
10.1101/2021.02.24.432729 — cancer biology — Posted on 2021-02-25
430 Stratification Of Chemotherapy-Treated Stage III Colorectal Cancer Patients Using Multiplexed Imaging And Single Cell Analysis Of T Cell Populations
Stachtea, X.; Loughrey, M. B.; Salvucci, M.; Lindner, A.; Cho, S.; McDonough, E.; Sood, A.; Graf, J.; Santamaria-Pang, A.; Corwin, A.; Laurent-Puig, P.; Dasgupta, S.; Van Schaeybroeck, S.; Lawler, M.; Prehn, J. H. M.; Ginty, F.; Longley, D. B.
10.1101/2021.02.24.432210 — cancer biology — Posted on 2021-02-25
432 SnapKin: a snapshot deep learning ensemble for kinase-substrate prediction from phosphoproteomics data
Lin, M.; Xiao, D.; Geddes, T. A.; Burchfield, J. G.; Parker, B.; Humphrey, S. J.; Yang, P.
10.1101/2021.02.23.432610 — bioinformatics — Posted on 2021-02-25
433 merlin v4.0: an updated platform for the reconstruction of high-quality genome-scale metabolic models
Capela, J.; Lagoa, D.; Rodrigues, R.; Cunha, E.; Cruz, F.; Barbosa, A.; Bastos, J.; Lima, D.; Ferreira, E. C.; Rocha, M.; Dias, O.
10.1101/2021.02.24.432752 — bioinformatics — Posted on 2021-02-25
435 Myo-inositol Oxygenase Overexpression Rescues Vitamin C Deficient Arabidopsis (vtc) Mutants
Acosta-Gamboa, L. M.; Nepal, N.; Medina-Jimenez, K.; Campbell, Z. C.; Cunningham, S. S.; Lee, J. A.; Lorence, A.
10.1101/2021.02.24.432757 — biochemistry — Posted on 2021-02-25
437 Characterising ontogeny of numerosity discrimination in zebrafish reveals multiple, numerical and non- numerical mechanisms.
Sheardown, E.; Torres-Perez, J. V.; Anagianni, S.; Fraser, S.; Vallortigara, G.; Butterworth, B.; Miletto-Petrazzini, M. E.; Brennan, C. H.
10.1101/2021.02.25.432846 — animal behavior and cognition — Posted on 2021-02-25
441 Towns and Trails Drive Carnivore Connectivity using a Step Selection Approach
Whittington, J.; Baron, R.; Hebblewhite, M.; Ford, A. T.; Paczkowski, J.
10.1101/2021.02.24.432739 — ecology — Posted on 2021-02-25
444 Prolonged epigenetic and synaptic plasticity alterations following single exposure to a psychedelic in mice
de la Fuente Revenga, M.; Zhu, B.; Guevara, C. A.; Naler, L. B.; Saunders, J. M.; Zhou, Z.; Toneatti, R.; Sierra, S.; Wolstenholme, J. T.; Beardsley, P. M.; Huntley, G. W.; Lu, C.; Gonzalez-Maeso, J.
10.1101/2021.02.24.432725 — neuroscience — Posted on 2021-02-25
446 Outcomes of Progranulin Gene Therapy in the Retina are Dependent on Time of Delivery
Zin, E. A.; Han, D.; Tran, J.; Morrison-Welch, N.; Visel, M.; Kuronen, M.; Flannery, J. G.
10.1101/2021.02.24.432570 — neuroscience — Posted on 2021-02-25
448 DYRK1A role in microtubule-based axonal transport regulates the retrograde dynamics of APP vesicles in human neurons
Fernandez Bessone, I.; Karmirian, K.; Goto-Silva, L.; Holubiec, M.; Navarro, J. L.; Martinez, E.; Saez, T. M.; Rehen, S.; Falzone, T. L.
10.1101/2021.02.25.432601 — neuroscience — Posted on 2021-02-25
449 Urea nitrogen recycling via gut symbionts increases in hibernators over the winter fast
Regan, M. D.; Chiang, E.; Liu, Y.; Tonelli, M.; Verdoorn, K. M.; Gugel, S. R.; Suen, G.; Carey, H. V.; Assadi-Porter, F. M.
10.1101/2021.02.24.432731 — physiology — Posted on 2021-02-25
450 Predictive visuo-motor communication through neural oscillations
Benedetto, A.; Binda, P.; Costagli, M.; Tosetti, M.; Morrone, M. C.
10.1101/2020.07.28.224949 — neuroscience — Posted on 2021-02-25
451 Short hydrogen bonds enhance non-aromatic protein-related fluorescence
Stephens, A. D.; Qaisrani, M. N.; Ruggiero, M. T.; Miron, G. D.; Morzan, U.; Gonzalez Lebrero, M. C.; Jones, S. T. E.; Poli, E.; Bond, A. D.; Woodhams, P. J.; Kleist, E. M.; Grisanti, L.; Gebauer, R.; Zeitler, J. A.; Credgington, D.; Hassanali, A.; Kaminski Schierle, G. S.
10.1101/2020.01.22.915306 — biophysics — Posted on 2021-02-25
454 Disease specific alterations in the olfactory mucosa of patients with Alzheimer's disease
Lampinen, R.; Fazaludeen, M. F.; Avesani, S.; Örd, T.; Penttilä, E.; Lehtola, J.-M.; Saari, T.; Hannonen, S.; Saveleva, L.; Kaartinen, E.; Acosta, F. F.; Cruz-Haces, M.; Löppönen, H.; Mackay-Sim, A.; Malm, T.; Kaikkonen-Maatta, M.; Koivisto, A.; White, A. R.; Giugno, R.; Chew, S.; Kanninen, K. M.
10.1101/2020.11.24.395947 — neuroscience — Posted on 2021-02-25
455 Branched-Chain Amino Acid Metabolism is Regulated by ERRα in Primary Human Myotubes and is Further Impaired by Glucose Loading in Type 2 Diabetes
Sjögren, R. J. O.; Rizo-Roca, D.; Chibalin, A. V.; Chorell, E.; Furrer, R.; Katayama, S.; Harada, J.; Karlsson, H. K. R.; Handschin, C.; Moritz, T.; Krook, A.; Näslund, E.; Zierath, J. R.
10.1101/2020.07.24.218099 — physiology — Posted on 2021-02-25
458 Integrative inference of transcriptional networks in Arabidopsis yields novel ROS signalling regulators
De Clercq, I.; Van de Velde, J.; Luo, X.; Liu, L.; Storme, V.; Van Bel, M.; Pottie, R.; Vaneechoutte, D.; Van Breusegem, F.; vandepoele, K.
10.1101/2020.08.11.245902 — plant biology — Posted on 2021-02-25
463 Dimerisation of APOBEC1 is dispensable for its RNA/DNA editing activity and modulates its availability
Chieca, M.; Montini, M. D.; Severi, F.; Lembo, G.; Donati, F.; Pecori, R.; Conticello, S. G.
10.1101/410803 — molecular biology — Posted on 2021-02-25
464 Toroidal topology of population activity in grid cells
Gardner, R. J.; Hermansen, E.; Pachitariu, M.; Burak, Y.; Baas, N. A.; Dunn, B. J.; Moser, M.-B.; Moser, E. I.
10.1101/2021.02.25.432776 — neuroscience — Posted on 2021-02-25
466 Effects of scent enrichment on behavioural andphysiological indicators of stress in zoo primates
Vaglio, S.; Kaburu, S.; Young, C.; Pearce, R.; Smith, S.; Tompkins, B. E.; Elwell, E.; Fontani, S.; Marliani, G.; Accorsi, P. A.
10.1101/2020.08.21.260679 — animal behavior and cognition — Posted on 2021-02-25
470 A mixture of generative models strategy helps humans generalize across tasks
HERCE CASTANON, S.; Cardoso-Leite, P.; Green, C. S.; Altarelli, I.; Schrater, P.; Bavelier, D.
10.1101/2021.02.16.431506 — neuroscience — Posted on 2021-02-25
471 Whole-body plethysmography revisited
Hülsmann, S.; Khan, A.; Hagos, L.; Hindermann, M.; Nägel, T.; Dullin, C.
10.1101/2021.02.24.432470 — physiology — Posted on 2021-02-25
476 scMoC: Single-Cell Multi-omics clustering
elTager, M.; Abdelaal, T.; Mahfouz, A.; Reinders, M.
10.1101/2021.02.24.432644 — bioinformatics — Posted on 2021-02-25
481 An integrated approach to identify environmental modulators of genetic risk factors for complex traits
Balliu, B.; Carcamo Orive, I.; Gloudemans, M. J.; Nachun, D. C.; Durrant, M. G.; Gazal, S.; Park, C. Y.; Knowles, D. A.; Wabitsch, M.; Quertermous, T.; Knowles, J. W.; Montgomery, S. B.
10.1101/2021.02.23.432608 — genomics — Posted on 2021-02-25
483 A high-quality Genome and Comparison of Short versus Long Read Transcriptome of the Palaearctic duck Aythya fuligula (Tufted Duck)
Mueller, R. C.; Ellström, P.; Howe, K.; Uliano-Silva, M.; Kuo, R. I.; Miedzinska, K.; Warr, A.; Fedrigo, O.; Haase, B.; Mountcastle, J.; Chow, W.; Torrance, J.; Wood, J.; Järhult, J. D.; Naguib, M. M.; Olsen, B.; Jarvis, E. D.; Smith, J.; Eöry, L.; Kraus, R. H.
10.1101/2021.02.24.432697 — genomics — Posted on 2021-02-25
485 The origin and drivers of Neotropical plant and tetrapod diversification
Meseguer, A. S.; Michel, A.; Fabre, P.-H.; Perez-Escobar, O.; Chomicki, G.; Riina, R.; Antonelli, A.; Antoine, P.-O.; Delsuc, F.; Condamine, F.
10.1101/2021.02.24.432517 — evolutionary biology — Posted on 2021-02-25
489 Downregulation of Extraembryonic Tension Controls Body Axis Formation in Avian Embryos
Kunz, D.; Wang, A.; Chan, C. U.; Pritchard, R. H.; Wang, W.; Gallo, F.; Bradshaw, C. R.; Terenzani, E.; Müller, K. H.; Huang, Y. Y. S.; Xiong, F.
10.1101/2021.02.24.432525 — developmental biology — Posted on 2021-02-25
490 A mouse model of occult intestinal colonization demonstrating antibiotic-induced outgrowth of carbapenem-resistant Enterobacteriaceae
Sim, C. K.; Saheb Kashaf, S.; Conlan, S.; Stacy, A.; Proctor, D. M.; Almeida, A.; Bouladoux, N.; Chen, M.; NISC Comparative Sequencing Program, ; Finn, R. D.; Belkaid, Y.; Segre, J. A.
10.1101/2021.02.24.432587 — microbiology — Posted on 2021-02-25
491 The immunophilin protein FKBPL and its peptide derivatives are novel regulators of vascular integrity and inflammation via NF-kappaB signaling
Annett, S. L.; Spence, S.; Garciarena, C.; Campbell, C.; Dennehy, M.; Drakeford, C.; Lai, J.; Dowling, J.; Moore, G.; Yakkundi, A.; Short, A.; Sharpe, D.; Furlong, F.; O'Donnell, J.; Cavalleri, G.; Kerrigan, S.; Tikhonova, I.; Johnson, P.; Kissenpfennig, A.; Robson, T.
10.1101/2021.02.24.431422 — immunology — Posted on 2021-02-25
496 Human blood lipoprotein predictions from 1H NMR spectra: protocol, model performances and cage of covariance
Khakimov, B.; C.J. Hoefsloot, H.; Mobaraki, N.; Aru, V.; Kristensen, M.; V. Lind, M.; Holm, L.; L Castro Mejia, J.; Nielsen, D. S.; Jacobs, D. M.; Smilde, A. K.; Engelsen, S. B.
10.1101/2021.02.24.432509 — systems biology — Posted on 2021-02-25
497 Optimized cDICE for efficient reconstitution of biological systems in giant unilamellar vesicles
Van de Cauter, L.; Fanalista, F.; van Buren, L.; De Franceschi, N.; Godino, E.; Bouw, S.; Danelon, C.; Dekker, C.; Koenderink, G. H.; Ganzinger, K. A.
10.1101/2021.02.24.432456 — synthetic biology — Posted on 2021-02-25
501 Characterization of growth and development of sorghum genotypes with differential susceptibility to Striga hermonthica
Kawa, D.; Taylor, T.; Thiombiano, B.; Musa, Z.; Vahldick, H.; Walmsley, A. J.; Bucksch, A. K.; Bouwmeester, H.; Brady, S. M.
10.1101/2021.02.24.432663 — plant biology — Posted on 2021-02-25
503 Disrupted circadian core-clock oscillations in Type 2 Diabetes are linked to altered rhythmic mitochondrial metabolism
Gabriel, B. M.; Altintas, A.; Smith, J. A. B.; Sardon Puig, L.; Zhang, X.; Linde Basse, A.; Laker, R. C.; Gao, H.; Liu, Z.; Dollet, L.; Treebak, J. T.; Zorzano, A.; Huo, Z.; Ryden, M.; Lanner, J. T.; Esser, K. A.; Barres, R.; Pillon, N. J.; Krook, A.; Zierath, J. R.
10.1101/2021.02.24.432683 — physiology — Posted on 2021-02-25
505 Structural and Functional Diversity among Agonist-Bound States of the GLP-1 Receptor
Cary, B. P.; Zhao, P.; Truong, T. T.; Piper, S. J.; Belousoff, M. J.; Danev, R.; Sexton, P. M.; Wootten, D.; Gellman, S. H.
10.1101/2021.02.24.432589 — pharmacology and toxicology — Posted on 2021-02-25
508 Nanomechanics of negatively supercoiled diaminopurine-substituted DNA
Salerno, D.; Mantegazza, F.; Cassina, V.; Cristofalo, M.; Shao, Q.; Finzi, L.; Dunlap, D.
10.1101/2021.02.24.432629 — biophysics — Posted on 2021-02-25
509 Quantitative analysis of neuronal mitochondrial movement reveals patterns resulting from neurotoxicity of rotenone and 6-hydroxydopamine
Simoes, R. F.; Pino, R.; Moreira-Soares, M.; Kovarova, J.; Neuzil, J.; Travasso, R.; Oliveira, P. J.; Cunha-Oliveira, T.; Pereira, F. B.
10.1101/2021.02.24.432715 — bioinformatics — Posted on 2021-02-25
510 Truly Privacy-Preserving Federated Analytics for Precision Medicine with Multiparty Homomorphic Encryption
Froelicher, D.; Troncoso-pastoriza, J. R.; Raisaro, J. L.; Cuendet, M.; Sa Sousa, J.; Fellay, J.; Hubaux, J.-P.
10.1101/2021.02.24.432489 — bioinformatics — Posted on 2021-02-25
514 A 48-Channel Receive Array Coil for Mesoscopic Diffusion-Weighted MRI of Human ex vivo Brain Imaging on the 3T Connectome Scanner
Scholz, A.; Etzel, R.; May, M. W.; Mahmutovic, M.; Tian, Q.; Ramos-Llorden, G.; Bilgic, B.; Witzel, T.; Stockmann, J. P.; Mekkaoui, C.; Wald, L. L.; Huang, S. Y.; Yendiki, A.; Keil, B.
10.1101/2021.02.24.432713 — bioengineering — Posted on 2021-02-25
516 Permeant Fluorescent Probes Visualize the Activation of SARM1 and Uncover an Anti-neurodegenerative Drug Candidate
Li, W. H.; Huang, K.; Cai, Y.; Wang, Q. W.; Zhu, W. J.; Hou, Y. N.; Wang, S.; Cao, S.; Zhao, Z. Y.; Xie, X. J.; Du, Y.; Lee, C.; Lee, H. C.; Zhang, H.; Zhao, Y. J.
10.1101/2021.02.24.432704 — biochemistry — Posted on 2021-02-25
520 Projecting ancient ancestry in modern-day Arabians and Iranians: a key role of the past exposed Arabo-Persian Gulf on human migrations
Ferreira, J. C.; Alshamali, F.; Montinaro, F.; Cavadas, B.; Torroni, A.; Pereira, L.; Raveane, A.; Fernandes, V.
10.1101/2021.02.24.432678 — genetics — Posted on 2021-02-25
523 Condensation of the Drosophila Nerve Cord is Oscillatory and depends on Coordinated Mechanical Interactions
Karkali, K.; Tiwari, P.; Singh, A.; Tlili, S.; Jorba, I.; Navajas, D.; Munoz Romero, J. J.; Saunders, T. E.; Martin-Blanco, E.
10.1101/2021.02.24.432750 — developmental biology — Posted on 2021-02-24
524 Biased removal and loading of centromeric histone H3 during reproduction underlies uniparental genome elimination
Marimuthu, M. P. A.; Maruthachalam, R.; Bondada, R.; Kuppu, S.; Tan, E.-H.; Britt, A.; Chan, S. S. W.; Comai, L.
10.1101/2021.02.24.432754 — cell biology — Posted on 2021-02-24
525 Dichotomous regulation of lysosomes by MYC and TFEB controls hematopoietic stem cell fate
Garcia-Prat, L.; Kaufmann, K. B.; Schneiter, F.; Voisin, V.; Murison, A.; Chen, J.; Chan-Seng-Yue, M.; Gan, O. I.; McLeod, J. L.; Smith, S. A.; Shoong, M. C.; Parris, D.; Pan, K.; Zeng, A. G. X.; Krivdova, G.; Gupta, K.; Takayanagi, S.-I.; Wagenblast, E.; Wang, W.; Lupien, M.; Schroeder, T.; Xie, S. Z.; Dick, J. E.
10.1101/2021.02.24.432720 — cell biology — Posted on 2021-02-24
526 The stress-sensing domain of activated IRE1α forms helical filaments in narrow ER membrane tubes
Carter, S. D.; Tran, N.-H.; De Maziere, A.; Ashkenazi, A.; Klumperman, J.; Jensen, G. J.; Walter, P.
10.1101/2021.02.24.432779 — cell biology — Posted on 2021-02-24
527 Mitochondrial and metabolic remodeling in human skin fibroblasts in response to glucose availability
Costa, C. F.; Pinho, S. A.; Pinho, S. L. C.; Miranda-Santos, I.; Bagshaw, O.; Stuart, J.; Oliveira, P. J.; Cunha-Oliveira, T.
10.1101/2021.02.24.432508 — cell biology — Posted on 2021-02-24
528 Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules
Fragasso, A.; Franceschi, N. D.; Stoemmer, P.; Van der Sluis, E. O.; Dietz, H.; Dekker, C.
10.1101/2021.02.24.432733 — biophysics — Posted on 2021-02-24
530 Dynamics of anteroposterior axis establishment in a mammalian embryo-like system
Anlas, K.; Gritti, N.; Oriola, D.; Arato, K.; Nakaki, F.; Lim, J. L.; Sharpe, J.; Trivedi, V.
10.1101/2021.02.24.432766 — developmental biology — Posted on 2021-02-24
533 Longitudinal high-resolution imaging through a flexible intravital imaging window
Jacquemin, G.; Benavente-Diaz, M.; Djaber, S.; Bore, A.; Dangles-Marie, V.; Surdez, D.; Tajbakhsh, S.; Fre, S.; Lloyd-Lewis, B.
10.1101/2021.02.24.432491 — cell biology — Posted on 2021-02-24
535 Selection of active defensive behaviors relies on extended amygdala dopamine D2 receptors
Castell, L.; Le Gall, V.; Cutando, L.; Puighermanal, E.; Jercog, D.; Tarot, P.; Tassou, A.; Harrus, A.-G.; Rubinstein, M.; Nouvian, R. M.; Rivat, C.; Herry, C.; Valjent, E.
10.1101/2021.02.24.432692 — neuroscience — Posted on 2021-02-24
536 Evaluating the reliability of human brain white matter tractometry
Kruper, J.; Yeatman, J. D.; Richie-Halford, A.; Bloom, D.; Grotheer, M.; Caffarra, S.; Kiar, G.; Karipidis, I. I.; Roy, E.; Rokem, A.
10.1101/2021.02.24.432740 — neuroscience — Posted on 2021-02-24
549 Spontaneous Facet Joint Osteoarthritis in NFAT1-Mutant Mice
Wang, J.; Lu, Q.; Mackay, M. J.; Liu, X.; Burton, D. C.; Asher, M. A.
10.1101/2021.02.23.432595 — molecular biology — Posted on 2021-02-24
550 Implications of central carbon metabolism in SARS-CoV-2 replication and disease severity
Krishnan, S.; Nordqvist, H.; Ambikan, A. T.; Gupta, S.; Sperk, M.; Svensson-Akusjarvi, S.; Mikaeloff, F.; Benfeitas, R.; Saccon, E.; Ponnan, S. M.; Rodriguez, J. E.; Nikouyan, N.; Odeh, A.; Ahlen, G.; Asghar, M.; Sallberg, M.; Vesterbacka, J.; Nowak, P.; Vegvari, A.; Sonnerborg, A.; Treutiger, C. J.; Neogi, U.
10.1101/2021.02.24.432759 — microbiology — Posted on 2021-02-24
551 Reciprocal repulsions instruct the precise assembly ofparallel hippocampal networks
Pederick, D. T.; Lui, J. H.; Gingrich, E. C.; Xu, C.; Wagner, M. J.; Liu, Y.; He, Z.; Quake, S. R.; Luo, L.
10.1101/2020.05.28.122242 — neuroscience — Posted on 2021-02-24
552 Identification of neural oscillations and epileptiform changes in human brain organoids
Samarasinghe, R. A.; Miranda, O. A.; Buth, J. E.; Mitchell, S.; Ferando, I.; Watanabe, M.; Allison, T. F.; Kurdian, A.; Fotion, N. N.; Gandal, M. J.; Golshani, P.; Plath, K.; Lowry, W. E.; Parent, J. M.; Mody, I.; Novitch, B. G.
10.1101/820183 — neuroscience — Posted on 2021-02-24
554 Bacteriophage self-counting in the presence of viral replication
Coleman, S.; Yao, T.; Nguyen, T. V. P.; Golding, I.; Igoshin, O. A.
10.1101/2021.02.24.432718 — systems biology — Posted on 2021-02-24
555 Characterisation of growth plate dynamics in murine models of osteoarthritis
Samvelyan, H. J.; Madi, K.; Tornqvist, A. E.; Javaheri, B.; Staines, K. A.
10.1101/2020.10.14.339119 — physiology — Posted on 2021-02-24
561 SARS-CoV-2 ORF6 disturbs nucleocytoplasmic trafficking to advance the viral replication
Miyamoto, Y.; Itoh, Y.; Suzuki, T.; Tanaka, T.; Sakai, Y.; Koido, M.; Hata, C.; Wan, C.-X.; Otani, M.; Moriishi, K.; Tachibana, T.; Kamatani, Y.; Yoneda, Y.; Okamoto, T.; Oka, M.
10.1101/2021.02.24.432656 — microbiology — Posted on 2021-02-24
564 Influenza virus ribonucleoprotein complex formation occurs in the nucleolus
Miyamoto, S.; Nakano, M.; Morikawa, T.; Hirabayashi, A.; Tamura, R.; Fujita, Y.; Hirose, N.; Muramoto, Y.; Noda, T.
10.1101/2021.02.24.432647 — microbiology — Posted on 2021-02-24
566 Development of Tribo-Electroceutical Fabrics for Potential Application in Self-sanitizing Personal Protective Equipment (PPE)
Bayan, S.; Adhikari, A.; Pal, U.; Ghosh, R.; Mondal, S.; Darbar, S.; Saha-Dasgupta, T.; Ray, S. K.; Pal, S. K.
10.1101/2021.02.23.432624 — microbiology — Posted on 2021-02-24
567 Sex-specific glycosylation of secreted immunomodulatory proteins in the filarial nematode Brugia malayi
Koussa, J.; Vitrinel, B.; Whitney, P. H.; Kasper, B.; Mahal, L. K.; Vogel, C.; Lustigman, S.; Salehi-Ashtiani, K.; Ghedin, E.
10.1101/2021.02.24.432741 — microbiology — Posted on 2021-02-24
568 Csf1r-GCaMP5 Reporter Mice Reveal Immune Cell Communication in Vitro and in Vivo
Taghdiri, N.; Calcagno, D. M.; Fu, Z. R.; Huang, K.; Kohler, R. H.; Weissleder, R.; Coleman, T. P.; King, K. R.
10.1101/2021.02.24.432710 — immunology — Posted on 2021-02-24
569 Cytotoxic lymphocytes target HIV-1 Gag through granzyme M-mediated cleavage
Saccon, E.; Mikaeloff, F.; Figueras Ivern, P.; Vegvari, A.; Sonnerborg, A.; Neogi, U.; van Domselaar, R.
10.1101/2021.02.24.432686 — immunology — Posted on 2021-02-24
570 An ultrasensitive GRAB sensor for detecting extracellular ATP in vitro and in vivo
Wu, Z.; He, K.; Chen, Y.; Li, H.; Pan, S.; Li, B.; Liu, T.; Wang, H.; Du, J.; Jing, M.; Li, Y.
10.1101/2021.02.24.432680 — neuroscience — Posted on 2021-02-24
573 Determinants of ligand-functionalized DNA nanostructure-cell interactions
Cremers, G. A. O.; Rosier, B. J. H. M.; Meijs, A.; Tito, N. B.; van Duijnhoven, S. M. J.; van Eenennaam, H.; Albertazzi, L.; de Greef, T. F. A.
10.1101/2021.02.24.432702 — synthetic biology — Posted on 2021-02-24
574 Discovery of a AhR flavonoid agonist that counter-regulates ACE2 expression in rodent models of inflammation and attenuates ACE2-SARS-CoV2 interaction in vitro
Biagioli, M.; Marchiano, S.; Roselli, R.; Di Giorgio, C.; Bellini, R.; Bordoni, M.; Gidari, A.; Sabbatini, S.; Francisci, D.; Fiorillo, B.; Catalanotti, B.; Distrutti, E.; Carino, A.; Zampella, A.; Costantino, G.; Fiorucci, S.
10.1101/2021.02.24.432203 — pharmacology and toxicology — Posted on 2021-02-24
575 The deacylase SIRT5 supports melanoma viability by regulating chromatin dynamics
Giblin, W.; Bringman-Rodenbarger, L.; Guo, A. H.; Kumar, S.; Monovich, A. C.; Mostafa, A. M.; Skinner, M. E.; Azar, M.; Mady, A. S. A.; Chung, C. H.; Kadambi, N.; Melong, K.-A.; Lee, H.-J.; Zhang, L.; Sajjakulnukit, P.; Trefely, S.; Varner, E. L.; Iyer, S.; Wang, M.; Wilmott, J. S.; Soyer, H. P.; Sturm, R. A.; Pritchard, A. L.; Andea, A.; Scolyer, R. A.; Stark, M. S.; Scott, D. A.; Fullen, D. R.; Bosenberg, M. W.; Chandrasekaran, S.; Nikolovska-Coleska, Z.; Verhaegen, M. E.; Snyder, N. W.; Rivera, M. N.; Osterman, A. L.; Lyssiotis, C. A.; Lombard, D. B.
10.1101/2020.09.07.286526 — cancer biology — Posted on 2021-02-24
576 Light-powered reactivation of flagella and contraction of microtubules network: towards building an artificial cell
Ahmad, R.; Kleineberg, C.; Nasirimarekani, V.; Su, Y. J.; Goli Pozveh, S.; Bae, A. J.; Bodenschatz, E.; Sundmacher, K.; Guido, I.; Vidakovich-Koch, T.; Gholami, A.
10.1101/2020.07.20.212191 — biophysics — Posted on 2021-02-24
578 AMPGAN v2: Machine Learning Guided Discovery of Anti-Microbial Peptides
Van Oort, C. M.; Ferrell, J. B.; Remington, J. M.; Wshah, S.; Li, J.
10.1101/2020.11.18.388843 — biophysics — Posted on 2021-02-24
580 Cryo-EM study on the homo-oligomeric ring formation of yeast TRiC/CCT subunits reveals TRiC ring assembly mechanism
Cong, Y.; Liu, C.; Wang, H.; Jin, M.; Han, W.; Wang, S.; Wang, Y.; Wang, F.; Su, C.; Hong, X.; Zhao, Q.
10.1101/2021.02.24.432666 — biochemistry — Posted on 2021-02-24
581 Innate behavior sequence progression by peptide-mediated interorgan crosstalk
Heredia, F.; Volonte, Y.; Pereirinha, J.; Fernandez-Acosta, M.; Casimiro, A. P.; Belem, C. G.; Viegas, F.; Tanaka, K.; Menezes, J.; Arana, M.; Cardoso, G. A.; Macedo, A.; Kotowicz, M.; Prado Spalm, F. H.; Dibo, M.; Monfardini, R. D.; Torres, T. T.; Mendes, C. S.; Garelli, A.; Gontijo, A. M.
10.1101/2020.10.10.334540 — animal behavior and cognition — Posted on 2021-02-24
582 Nuclear Hormone Receptor NHR-49 controls a HIF-1-independent hypoxia adaptation pathway in Caenorhabditis elegans
Doering, K. R. S.; Cheng, X.; Milburn, L.; Ratnappan, R.; Ghazi, A.; Miller, D. L.; Taubert, S.
10.1101/2021.02.24.432575 — genetics — Posted on 2021-02-24
587 Cyclophilin A regulates protein phase separation and mitigates haematopoietic stem cell aging
Maneix, L.; Iakova, P.; Moree, S. E.; King, J. C. K.; Sykes, D. B.; Hill, C. T.; Saez, B.; Spooner, E.; Krause, D. S.; Sahin, E.; Berk, B. C.; Scadden, D. T.; Catic, A.
10.1101/2021.02.24.432737 — cell biology — Posted on 2021-02-24
588 Targeting an anchored phosphatase-deacetylase unit restores renal ciliary homeostasis.
Gopalan, J.; Omar, M.; Roy, A.; Cruz, N. M.; Falcone, J.; Forbush, K.; Himmelfarb, J.; Freedman, B.; Scott, J. D.
10.1101/2021.02.24.432764 — cell biology — Posted on 2021-02-24
590 RNase R, a new virulence determinant of Streptococcus pneumoniae
Barria, C.; Mil-Homens, D.; Fialho, A. M.; Arraiano, C. M.; Domingues, S.
10.1101/2021.02.24.432507 — molecular biology — Posted on 2021-02-24
591 A genome-wide CRISPR screen identifies interactors of the autophagy pathway as conserved coronavirus targets
Kratzel, A.; Kelly, J. N.; Brueggemann, Y.; Portmann, J.; V'kovski, P.; Todt, D.; Ebert, N.; Steinmann, E.; Dijkman, R.; Zimmer, G.; Pfaender, S.; Thiel, V.
10.1101/2021.02.24.432634 — microbiology — Posted on 2021-02-24
593 The nonstructural protein 5 of coronaviruses antagonizes GSDMD-mediated pyroptosis by cleaving and inactivating its pore-forming p30 fragment
Shi, F.; Lv, Q.; Wang, T.; Xu, J.; Xu, W.; Shi, Y.; Fu, X.; Yang, T.; Yang, Y.; Zhuang, L.; Fang, W.; Gu, J.; Li, X.
10.1101/2021.02.23.432418 — microbiology — Posted on 2021-02-24
594 Increased transmission of SARS-CoV-2 lineage B.1.1.7 (VOC 2020212/01) is not accounted for by a replicative advantage in primary airway cells or antibody escape
Brown, J. C.; Goldhill, D. H.; Zhou, J.; Peacock, T. P.; Frise, R.; Goonawardane, N.; Baillon, L.; Kugathasan, R.; Pinto, A.; McKay, P. F.; Hassard, J.; Moshe, M.; Singanayagam, A.; Burgoyne, T.; PHE Virology Consortium, ; Barclay, W. S.
10.1101/2021.02.24.432576 — microbiology — Posted on 2021-02-24
595 Fiber-associated Lachnospiraceae reduce colon tumorigenesis by modulation of the tumor-immune microenvironment
Almeida, A. S.; Tran, T. T. T.; Ghosh, T. S.; Ribiere, C.; Foley, C.; Alves, L. A.; Pellanda, P.; Frei, W.; Hueston, C. M.; Kumar, R.; Flemer, B.; Sequeira, I.; O'Riordain, M.; Shanahan, F.; O'Toole, P. W.
10.1101/2021.02.24.432654 — microbiology — Posted on 2021-02-24
596 Comparative biofilm assays using Enterococcus faecalis OG1RF identify new determinants of biofilm formation
Willett, J. L. E.; Dale, J. L.; Kwiatkowski, L. M.; Powers, J. L.; Korir, M. L.; Kohli, R.; Barnes, A. M. T.; Dunny, G. M.
10.1101/2021.02.24.432758 — microbiology — Posted on 2021-02-24
600 Genetic determinants of intrinsic antibiotic tolerance in Mycobacterium avium
Matern, W. M.; Parker, H.; Danchik, C.; Hoover, L.; Bader, J.; Karakousis, P. C.
10.1101/2021.02.23.432616 — microbiology — Posted on 2021-02-24
601 Targeting of the NLRP3 Inflammasome for early COVID-19
Marchetti, C.; Mould, K.; Tengesdal, I. W.; Janssen, W. J.; Dinarello, C. A.
10.1101/2021.02.24.432734 — immunology — Posted on 2021-02-24
603 Rapid adaptation and remote delivery of undergraduate research training during the COVID 19 Pandemic
Yang Yowler, J.; Knier, K.; WareJoncas, Z.; Ehlers, S. L.; Ekker, S. C.; Guasp Reyes, F.; Horazdovsky, B. F.; Mueller, G.; Morales Gomez, A.; Sood, A.; Sussman, C. R.; Scholl, L. M.; Weavers, K. M.; Pierret, C.
10.1101/2021.02.24.432694 — scientific communication and education — Posted on 2021-02-24
606 Acute and chronic effects of exams week on cortisol production in undergraduate students
Borghi, F.; da Silva, P. C.; Canova, F.; Souza, A. L.; Barbedo Arouca, A.; Grassi-Kassisse, D. M.
10.1101/2021.02.23.432585 — physiology — Posted on 2021-02-24
607 Regression QSAR Models for Predicting HIV-1 Integrase Inhibitors
Ha, C. H. X.; Lee, N. K.; Rahman, T.; Hwang, S. S.; Yam, W. K.; Chee, X. W.
10.1101/2021.02.23.432583 — pharmacology and toxicology — Posted on 2021-02-24
610 The Gossypium stocksii genome as a novel resource for cotton improvement
Grover, C. E.; Yuan, D.; Arick, M. A.; Miller, E. R.; Hu, G.; Peterson, D. G.; Wendel, J. F.; Udall, J. A.
10.1101/2021.02.23.432605 — genomics — Posted on 2021-02-24
611 Chemoenzymatic labeling of DNA methylation patterns for single-molecule epigenetic mapping
Gabrieli, T.; Michaeli, Y.; Avraham, S.; Torchinsky, D.; Juhasz, M.; Coruh, C.; Arbib, N.; Zhou, Z. S.; Law, J. A.; Weinhold, E.; Ebenstein, Y.
10.1101/2021.02.24.432628 — genomics — Posted on 2021-02-24
612 The oncogenic transcription factor FUS-CHOP can undergo nuclear liquid-liquid phase separation
Owen, I.; Yee, D.; Wyne, H.; Perdikari, T. M.; Johnson, V.; Smyth, J.; Kortum, R.; Fawzi, N. L.; Shewmaker, F.
10.1101/2021.02.24.432743 — cell biology — Posted on 2021-02-24
614 Small-molecule inhibitors of the RNA m6A demethylase FTO potently support the survival of dopamine neurons
Selberg, S.; Li-Ying, Y.; Bondarenko, O.; Kankuri, E.; Seli, N.; Kovaleva, V.; Herodes, K.; Saarma, M.; Karelson, M.
10.1101/2021.02.23.432419 — neuroscience — Posted on 2021-02-24
615 Cell Communication Network factor 4 promotes tumor-induced immunosuppression in melanoma
Fernandez, A.; Deng, W.; McLaughlin, S. L.; Pirkey, A. C.; Rellick, S.; Klinke, D. J.
10.1101/2021.02.23.432584 — cancer biology — Posted on 2021-02-24
616 Chromatin accessibility changes at intergenic regions associates with ovarian cancer drug resistance
Gallon, J.; Loomis, E.; Curry, E.; Martin, N.; Brody, L.; Garner, I.; Brown, R.; Flanagan, J. M.
10.1101/2021.02.24.432641 — cancer biology — Posted on 2021-02-24
617 p97/VCP induces GLI1 to control XBP1-dependent endoplasmic reticulum stress transcriptional response
Barroso, K.; Almada, L. L.; Olson, R.; Auner, H.; Pedeux, R.; IOVANNA, J. L.; Chevet, E.; Fernandez-Zapico, M. E.
10.1101/2021.02.24.432555 — cancer biology — Posted on 2021-02-24
619 MYC promotes immune-suppression in TNBC via inhibition of IFN signaling
Zimmerli, D.; Brambillasca, C. S.; Talens, F.; Bhin, J.; Bhattacharya, A.; Joosten, S. E. P.; Moises da Silva, A.; Wellenstein, M. D.; Kersten, K.; de Boo, M.; Roorda, M.; Henneman, L.; de Bruijn, R.; Annunziato, S.; van der Burg, E.; Drenth, A. P.; Lutz, C.; van der Ven, M.; Wessels, L.; de Visser, K. E.; Zwart, W.; Fehrmann, R. S. N.; van Vugt, M. A. T. M.; Jonkers, J.
10.1101/2021.02.24.432659 — cancer biology — Posted on 2021-02-24
621 Marine heatwaves depress metabolic activity and impair cellular acid-base homeostasis in reef-building corals regardless of bleaching susceptibility
Innis, T.; Allen-Waller, L.; Brown, K. T.; Sparagon, W.; Carlson, C.; Kruse, E.; Huffmyer, A. S.; Nelson, C. E.; Putnam, H. M.; Barott, K. L.
10.1101/2021.02.23.432550 — ecology — Posted on 2021-02-24
623 Cerebellar connectivity maps embody individual adaptive behavior
Spaeth, L.; BAHUGUNA, J.; Gagneux, T.; Dorgans, K.; Sugihara, I.; Poulain, B.; Battaglia, D.; Isope, P.
10.1101/2021.02.24.432563 — neuroscience — Posted on 2021-02-24
629 Characterization of the different behaviours exhibited by juvenile grey mullet (Mugil cephalus) under rearing conditions
Jimenez Rivera, J. A.; Boglino, A.; Linares Cordova, J. F.; Duncan, N. J.; Ruiz Gomez, M. d. L.; Rey Planellas, S.; Ibarra Zatarain, Z.
10.1101/2021.02.23.432396 — animal behavior and cognition — Posted on 2021-02-24
630 Chronic Stress Alters Astrocyte Morphology in Mouse Prefrontal Cortex
Codeluppi, S. A.-M.; Chatterjee, D.; Prevot, T. D.; Misquitta, K. A.; Sibille, E.; Banasr, M.
10.1101/2021.02.23.432559 — animal behavior and cognition — Posted on 2021-02-24
632 Combinatorial transcription factor profiles predict mature and functional human islet α and β cells
Shrestha, S.; Saunders, D. C.; Walker, J. T.; Camunas-Soler, J.; Dai, X.-Q.; Haliyur, R.; Aramandla, R.; Poffenberger, G.; Prasad, N.; Bottino, R.; Stein, R.; Cartailler, J.-P.; Parker, S. C. J.; MacDonald, P. E.; Levy, S. E.; Powers, A. C.; Brissova, M.
10.1101/2021.02.23.432522 — genomics — Posted on 2021-02-24
635 Evolutionary priming and transition to the ectomycorrhizal habit in an iconic lineage of mushroom-forming fungi: is preadaptation a requirement?
Looney, B. P.; Miyauchi, S.; Morin, E.; Drula, E.; Courty, P.-E.; Kohler, A. P.; Lindquist, E.; Kuo, A.; LaButti, K.; Pangilinan, J.; Lipzen, A.; Riley, R.; Andreopoulos, W.; He, G.; Johnson, J.; Barry, K. W.; Grigoriev, I. V.; Nagy, L. G.; Hibbett, D.; Henrissat, B.; Matheny, P. B.; Labbe, J.; Martin, F. M.
10.1101/2021.02.23.432530 — evolutionary biology — Posted on 2021-02-24
637 The developing mouse coronal suture at single-cell resolution
Farmer, D. T.; Mlcochova, H.; Zhou, Y.; Koelling, N.; Wang, G.; Ashley, N.; Maxson, R. E.; Wilkie, A. O.; Crump, J. G.; Twigg, S. R.
10.1101/2021.02.24.432636 — developmental biology — Posted on 2021-02-24
640 Widespread ripples synchronize human cortical activity
Dickey, C. W.; Verzhbinsky, I. A.; Jiang, X.; Rosen, B. Q.; Kajfez, S.; Stedelin, B.; Shih, J. J.; Ben-Haim, S.; Raslan, A. M.; Madsen, J. R.; Eskandar, E. N.; Gonzalez-Martinez, J.; Cash, S. S.; Halgren, E.
10.1101/2021.02.23.432582 — neuroscience — Posted on 2021-02-24
641 Altered environmental perception by parental stress and depression vulnerability: impact on mothers and offspring
Alves, R. L.; Portugal, C. C.; Lopes, I. M.; Oliveira, P.; Alves, C. J.; Barbosa, F.; Summavielle, T.; Magalhaes, A.
10.1101/2021.02.23.432580 — neuroscience — Posted on 2021-02-24
647 Topography and motion of the acid-sensing ion channel intracellular domains
Couch, T.; Berger, K.; Kneisley, D. L.; McCullock, T. W.; Kammermeier, P. J.; MacLean, D. M.
10.1101/2021.02.23.432526 — physiology — Posted on 2021-02-24
649 Likelihood-based Tests for Detecting CircadianRhythmicity and Differential Circadian Patterns in Transcriptomic Applications
Ding, H.; Meng, L.; Liu, A. C.; Gumz, M. L.; Bryant, A. J.; Mcclung, C. A.; Tseng, G. C.; Esser, K. A.; Huo, Z.
10.1101/2021.02.23.432538 — bioinformatics — Posted on 2021-02-24
650 PredictProtein - Predicting Protein Structure and Function for 29 Years
Bernhofer, M.; Dallago, C.; Karl, T.; Satagopam, V.; Heinzinger, M.; Littmann, M.; Olenyi, T.; Qiu, J.; Schuetze, K.; Yachdav, G.; Ashkenazy, H.; Ben-Tal, N.; Bromberg, Y.; Goldberg, T.; Kajan, L.; O'Donoghue, S.; Sander, C.; Schafferhans, A.; Schlessinger, A.; Vriend, G.; Mirdita, M.; Gawron, P.; Gu, W.; Jarosz, Y.; Trefois, C.; Steinegger, M.; Schneider, R.; Rost, B.
10.1101/2021.02.23.432527 — bioinformatics — Posted on 2021-02-24
653 Adaptive introgression and standing genetic variation, two facilitators of adaptation to high latitudes in European aspen (Populus tremula L.)
Rendon-Anaya, M.; Wilson, J.; Sveinsson, S.; Fedorkov, A.; Cottrell, J.; Bailey, M. E. S.; Rungis, D.; Lexer, C.; Jansson, S.; Robinson, K. M.; Street, N. R.; Ingvarsson, P. K.
10.1101/2021.02.23.432466 — evolutionary biology — Posted on 2021-02-24
656 A framework for selectively breeding corals for assisted evolution
Humanes, A.; Bythell, J. C.; Beauchamp, E. A.; Carl, M. K.; Craggs, J. R.; Edwards, A. J.; Golbuu, Y.; Lachs, L.; Randle, J. L.; Martinez, H. M.; Palmowski, P.; Paysinger, F.; van der Steeg, E. J.; Sweet, M.; Treumann, A.; Guest, J. R.
10.1101/2021.02.23.432469 — ecology — Posted on 2021-02-24
658 IFNγ and iNOS-mediated alterations in the bone marrow and thymus and its impact on Mycobacterium avium-induced thymic atrophy
Barreira-Silva, P.; Melo-Miranda, R.; Nobrega, C.; Roque, S.; Serre-Miranda, C.; Borges, M.; de Sa Calcada, D.; Behar, S. M.; Appelberg, R.; Correia-Neves, M.
10.1101/2021.02.23.432464 — immunology — Posted on 2021-02-24
663 Predicted distribution of a rare and understudied forest carnivore: Humboldt martens (Martes caurina humboldtensis)
Moriarty, K. M.; Thompson, J.; Delheimer, M. S.; Barry, B. R.; Linnell, M. A.; Levi, T.; Hamm, K.; Early, D.; Gamblin, H.; Szykman Gunther, M.; Ellison, J. L.; Prevey, J.; Hartman, J.; Davis, R.
10.1101/2021.02.05.429381 — ecology — Posted on 2021-02-24
664 Host-associated fungal communities are determined by host phylogeny and exhibit widespread associations with the bacterial microbiome
Harrison, X. A.; McDevitt, A.; Dunn, J. C.; Griffiths, S.; Benvenuto, C.; Birtles, R.; Boubli, J. P.; Bown, K.; Bridson, C.; Brooks, D.; Browett, S. S.; Carden, R. F.; Chantrey, J.; Clever, F.; Coscia, I.; Edwards, K. L.; Ferry, N.; Goodhead, I.; Highlands, A.; Hopper, J.; Jackson, J. A.; Jehle, R.; Kaizer, M.; King, T.; Lea, J. M.; Lenka, J. L.; McCubbin, A.; McKenzie, J.; Moraes, B.; O'Meara, D. B.; Pescod, P.; Preziosi, R. F.; Rowntree, J. K.; Shultz, S.; Silk, M. J.; Stockdale, J. E.; Symondson, W. O.; de la Pena, M.; Walker, S. L.; Wood, M. D.; Antwis, R. E.
10.1101/2020.07.07.177535 — ecology — Posted on 2021-02-24
665 Artemisia annua L. extracts inhibit the in vitro replication of SARS-CoV-2 and two of its variants
Nair, M. S.; Huang, Y.; Fidock, D. A.; Polyak, S. J.; Wagoner, J.; Towler, M.; Weathers, P.
10.1101/2021.01.08.425825 — microbiology — Posted on 2021-02-24
667 Genetically Engineered Strains for Combinatorial Cardiovascular Optobiology
Lee, F. K.; Lee, J. C.; Shui, B.; Reining, S.; Jibilian, M.; Small, D. M.; Jones, J. S.; Allan-Rahill, N. H.; Lamont, M. R.; Rizzo, M. A.; Tajada, S.; Navedo, M. F.; Santana, L. F.; Nishimura, N.; Kotlikoff, M. I.
10.1101/2021.01.21.427692 — physiology — Posted on 2021-02-24
670 Co-translational folding of the first transmembrane domain of ABC-transporter CFTR is supported by assembly with the first cytosolic domain
Kleizen, B.; van Willigen, M.; Mijnders, M.; Peters, F. M.; Grudniewska, M. K.; Hillenaar, T. M.; Thomas, A. S.; Kooijman, L.; Peters, K. W.; Frizzell, R.; van der Sluijs, P.; Braakman, I.
10.1101/2020.12.19.423590 — biochemistry — Posted on 2021-02-24
675 The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals
Torrence, M. E.; MacArthur, M. R.; Hosios, A. M.; Valvezan, A.; Asara, J. M.; Mitchell, J. R.; Manning, B. D.
10.1101/2020.10.03.324186 — cell biology — Posted on 2021-02-24
676 A novel DNA-binding protein regulates sexual differentiation in malaria parasites and is essential for transmission.
Campelo Morillo, R.; Tong, X.; Xie, W.; Lenz, T.; Batugedara, G.; Tabassum, N.; Orchard, L. M.; Daher, W.; Patel, D.; Noble, W. S.; Llinas, M.; Le Roch, K. G.; Kafsack, B. F. C.
10.1101/2020.10.26.352583 — microbiology — Posted on 2021-02-24
677 Two opposite voltage-dependent currents control the unusual early development pattern of embryonic Renshaw cell electrical activity
Boeri, J.; Meunier, C.; Le Corronc, H.; Branchereau, P.; Timofeeva, Y.; Lejeune, F.-X.; Mouffle, C.; Arulkandarajah, H.; Mangin, J. M.; Legendre, P.; Czarnecki, A.
10.1101/2020.06.18.158931 — neuroscience — Posted on 2021-02-24
681 INSULIN-LIKE GROWTH FACTOR I SENSITIZATION REJUVENATES SLEEP PATTERNS IN OLD MICE
Torres Aleman, I.; Zegarra-Valdivia, J. A.; Fernandes, J.; Trueba-Saiz, A.; Fernandez de Sevilla, M. E.; Pignatelli, J.; Suda, K.; Martinez Rachadell, L.; Fernandez, A. M.; Esparza, J.; Vega, M.; Nunez, A.
10.1101/2021.02.23.432494 — neuroscience — Posted on 2021-02-24
683 Activity-induced gene expression and long-range enhancer-promoter contacts in cohesin-deficient neurons
Calderon, L.; Weiss, F. D.; Beagan, J. A.; Oliveira, M. S.; Wang, Y.-F.; Carroll, T.; Dharmalingam, G.; Gong, W.; Tossell, K.; de Paola, V.; Whilding, C.; Ungless, M. A.; Fisher, A. G.; Phillips-Cremins, J. E.; Merkenschlager, M.
10.1101/2021.02.24.432639 — genomics — Posted on 2021-02-24
684 Apoptotic Extracellular Vesicles (ApoEVs) Safeguard Liver Homeostasis and Regeneration via Assembling an ApoEV-Golgi Organelle
Sui, B.; Wang, R.; Chen, C.; Kou, X.; Wu, D.; Tu, H.-C.; Wang, Y.; Liu, Y.; Jacobson, O.; Chen, X.; Liu, H.; Kwok, R. T. K.; Tang, B. Z.; Yan, H.; Wang, M.; Xiang, L.; Yan, X.; Fu, Y.; Zhang, X.; Tang, J.; Ma, L.; Lu, L.; Jin, Y.; Shi, S.
10.1101/2021.02.24.432630 — cell biology — Posted on 2021-02-24
686 Balancing selection maintains hyper-divergent haplotypes in C. elegans
Lee, D.; Zdraljevic, S.; Stevens, L.; Wang, Y.; Tanny, R. E.; Crombie, T. A.; Cook, D. E.; Webster, A. K.; Chirakar, R.; Baugh, L. R.; Sterken, M.; Braendle, C.; Felix, M.-A.; Rockman, M.; Andersen, E. C.
10.1101/2020.07.23.218420 — evolutionary biology — Posted on 2021-02-24
687 Mapping the probability of forest snowdisturbances in Finland
Suvanto, S.; Lehtonen, A.; Nevalainen, S.; Lehtonen, I.; Viiri, H.; Strandström, M.; Peltoniemi, M.
10.1101/2020.12.23.424139 — ecology — Posted on 2021-02-24
688 Year-round dynamics of amplicon sequence variant communities differ among eukaryotes, Mimiviridae, and prokaryotes in a coastal ecosystem
Prodinger, F.; Endo, H.; Takano, Y.; Li, Y.; Tominaga, K.; Isozaki, T.; Blanc-Mathieu, R.; Gotoh, Y.; Tetsuya, H.; Taniguchi, E.; Nagasaki, K.; Yoshida, T.; Ogata, H.
10.1101/2021.02.02.429489 — microbiology — Posted on 2021-02-24
689 The landscape of PrPC biosynthesis revealed by an arrayed genome-wide interference screen
Heinzer, D.; Avar, M.; Pease, D. P.; Dhingra, A.; Yin, J.-A.; Schaper, E.; Dogancay, B.; Emmenegger, M.; Spinelli, A.; Maggi, K.; Chincisan, A.; Mead, S.; Hornemann, S.; Heutink, P.; Aguzzi, A.
10.1101/2021.01.28.428672 — neuroscience — Posted on 2021-02-24
690 The epoxyeicosatrienoic pathway is intact in endothelial and smooth muscle cells exposed to aldosterone excess
Brunnenkant, L.; Meng, Y.; Sun, J.; Gonzalez Marques, J.; Koletzko, B.; Mederos y Schnitzler, M.; Gudermann, T.; Williams, T. A.; Beuschlein, F.; Heinrich, D. A.; Adolf, C.; Reincke, M.; Schneider, H.
10.1101/2021.02.04.429624 — physiology — Posted on 2021-02-24
693 Chromosome-length genome assembly and structural variations of the primal Basenji dog (Canis lupus familiaris) genome
Edwards, R. J.; Field, M. A. J.; Ferguson, J. M.; Dudchenko, O.; Keilwagen, J.; Rosen, B. D.; Johnson, G. S.; Rice, E. S.; Hillier, L.; Hammond, J. M.; Tomwarnicki, S. G.; Omer, A.; Skvortsova, K.; Bogdanovic, O.; Zammit, R. A.; Aiden, E. L.; Warren, W. C.; Ballard, J. W. O.
10.1101/2020.11.11.379073 — genomics — Posted on 2021-02-24
694 Rate-of-change analysis in palaeoecology revisited: a new approach
Mottl, O.; Grytes, J.-A.; Seddon, A. W. R.; Steinbauer, M. J.; Bhatta, K. P.; Felde, V. A.; Flantua, S. G. A.; Birks, H. J. B.
10.1101/2020.12.16.422943 — ecology — Posted on 2021-02-24
699 Antiparasitic effect of stilbene and terphenyl compounds against Trypanosoma cruzi parasites
Bruno, F.; Castelli, G.; Vitale, F.; Catanzaro, S.; Badaco, V. V.; Roberti, M.; Colomba, C.; Cascio, A.; Tolomeo, M.
10.1101/2021.02.23.432446 — microbiology — Posted on 2021-02-23
701 Design principles of acidic transcriptional activation domains
Staller, M. V.; Ramirez, E.; Holehouse, A. S.; Pappu, R. V.; Cohen, B. A.
10.1101/2020.10.28.359026 — systems biology — Posted on 2021-02-23
703 A large-scale transcriptome-wide association study (TWAS) of ten blood cell phenotypes reveals complexities of TWAS fine-mapping
Tapia, A. L.; Rowland, B. T.; Rosen, J. D.; Preuss, M.; Young, K.; Graff, M.; Choquet, H.; Couper, D. J.; Buyske, S.; Bien, S. A.; Jorgenson, E.; Kooperberg, C.; Loos, R. J. F.; Morrison, A. C.; North, K. E.; Yu, B.; Reiner, A. P.; Li, Y.; Raffield, L. M.
10.1101/2021.02.23.432444 — genetics — Posted on 2021-02-23
704 Core circadian clock transcription factor BMAL1 regulates mammary epithelial cell growth, differentiation, and milk component synthesis
Casey, T.; Suarez-Trujillo, A. M.; Cummings, S. M.; Huff, K.; Crodian, J.; Bhide, K. M.; Aduwari, C. M.; Teeple, K. M.; Shamay, A.; Mabjeesh, S. J.; San Miguel, P. M.; Thimmapuram, J. M.; Plaut, K. M.
10.1101/2021.02.23.432439 — cell biology — Posted on 2021-02-23
708 Increased biting rate and decreased Wolbachia density in irradiated mosquitoes: safety issues in the framework of genetic control strategies
Moretti, R.; Lampazzi, E.; Fabbri, G.; Lombardi, G.; Damiani, C.; Pioli, C.; Desiderio, A.; Serrao, A.; Calvitti, M.
10.1101/2021.02.23.432445 — microbiology — Posted on 2021-02-23
709 The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation
Meyers, J.; Ramanathan, M.; Shanderson, R.; Donohue, L.; Ferguson, I.; Guo, M.; Rao, D.; Miao, W.; Reynolds, D.; Yang, X.; Zhao, Y.; Yang, Y.-Y.; Wang, Y.; Khavari, P.
10.1101/2021.02.23.432450 — microbiology — Posted on 2021-02-23
711 A tale of two gradients: Differences between the left and right hemispheres predict semantic cognition and visual reasoning
Gonzalez Alam, T. R.; Mckeown, B. L. A.; Gao, Z.; Bernhardt, B.; Vos de Wael, R.; Margulies, D. S.; Smallwood, J.; Jefferies, E.
10.1101/2021.02.23.432529 — neuroscience — Posted on 2021-02-23
712 Dense Functional and Molecular Readout of a Circuit Hub in Sensory Cortex
Condylis, C.; Ghanbari, A.; Manjrekar, N.; Bistrong, K.; Yao, S.; Yao, Z.; Nguyen, T. N.; Zeng, H.; Tasic, B.; Chen, J. L.
10.1101/2021.02.23.432355 — neuroscience — Posted on 2021-02-23
713 Mask, the Drosophila Ankyrin Repeat and KH domain-containing protein, regulates microtubule dynamics
Martinez, D. A.; Zhu, M.; Guidry, J. J.; Majeste, N.; Mao, H.; Yanofsky, S.; Tian, X.; Wu, C.
10.1101/2020.04.22.056051 — neuroscience — Posted on 2021-02-23
714 Cellular, physiological, and behavioral validation of a CRFR1:Cre-tdTomato transgenic rat for use in basic neuroscience research
Weera, M. M.; Agoglia, A. E.; Douglass, E. A.; Jiang, Z.; Rajamanikam, S.; Shackett, R. S.; Justice, N. J.; Herman, M. A.; Gilpin, N. W.
10.1101/2021.02.23.432551 — neuroscience — Posted on 2021-02-23
717 Cancer blues? A validated judgment bias task suggests pessimism in nude mice with tumors
Resasco, A.; MacLellan, A.; Ayala, M. A.; Kitchenham, L.; Edwards, M.; Lam, S.; Dejardin, S.; Mason, G.
10.1101/2021.02.13.431089 — animal behavior and cognition — Posted on 2021-02-23
718 Identification of promising oilseed rape genotypes for the tropical regions of Iran using multivariate analysis
Bakhshi, B.; Amiri Oghan, H.; Alizadeh, B.; Rameeh, V.; Payghamzadeh, K.; Kiani, D.; Rabiee, M.; Rezaizad, A.; Shiresmaeili, G.; Dalili, A.; Kia, S.
10.1101/2021.02.23.431199 — genetics — Posted on 2021-02-23
720 Host-specific gene expression as a tool for introduction success in populations of generalist Naupactus parthenogenetic weevils
Mackay-Smith, A.; Dornon, M. K.; Lucier, R.; Okimoto, A.; Mendonca de Sousa, F.; Rodriguero, M.; Confalonieri, V.; Lanteri, A.; Sequeira, A.
10.1101/2021.02.23.432442 — evolutionary biology — Posted on 2021-02-23
723 Surfactin stimulated by pectin molecular patterns and root exudates acts as a key driver of Bacillus-plant mutualistic interaction
Hoff, G.; Arguelles Arias, A.; Boubsi, F.; Prsic, J.; Meyer, T.; Ibrahim, H. M. M.; Steels, S.; Luzuriaga, P.; Legras, A.; Franzil, L.; Lequart, M.; Rayon, C.; Osorio, V.; de Pauw, E.; Lara, Y.; Deboever, E.; de Coninck, B.; Jacques, P.; Deleu, M.; Petit, E.; Van Wuytswinkel, O.; Ongena, M.
10.1101/2021.02.22.432335 — microbiology — Posted on 2021-02-23
725 Automated Segmentation of Amyloid-β Stained Whole Slide Images of Brain Tissue
Lai, Z.; Guo, R.; Xu, W.; Hu, Z.; Mifflin, K.; DeCarli, C.; Dugger, B. N.; Cheung, S.-c.; Chuah, C.-N.
10.1101/2020.11.13.381871 — neuroscience — Posted on 2021-02-23
727 Rewritable Two-Dimensional DNA-Based Data Storage with Machine Learning Reconstruction
Pan, C.; Tabatabaei, S. K.; Tabatabaei Yazdi, S. M. H.; Hernandez, A. G.; Schroeder, C. M.; Milenkovic, O.
10.1101/2021.02.22.432304 — synthetic biology — Posted on 2021-02-23
728 Genetically Engineered Strains for Combinatorial Cardiovascular Optobiology
Lee, F. K.; Lee, J. C.; Shui, B.; Reining, S.; Jibilian, M.; Small, D. M.; Jones, J. S.; Allan-Rahill, N. H.; Lamont, M. R.; Rizzo, M. A.; Tajada, S.; Navedo, M. F.; Santana, L. F.; Nishimura, N.; Kotlikoff, M. I.
10.1101/2021.01.21.427692 — physiology — Posted on 2021-02-23
729 Oncofusion-driven de novo enhancer assembly promotes malignancy in Ewing sarcoma via aberrant expression of the stereociliary protein LOXHD1
Deng, Q.; Natesan, R.; Cidre-Aranaz, F.; Arif, S.; Liu, Y.; Rasool, R.; Wang, P.; Cramer, Z.; Chou, M.; Kumar-Sinha, C.; Weber, K.; Eisinger-Mathason, K.; Grillet, N.; Grunewald, T. G. P.; asangani, i. a.
10.1101/2021.02.22.432287 — cancer biology — Posted on 2021-02-23
730 Wrinkle force microscopy: a new machine learning based approach to predict cell mechanics from images
Li, H.; Matsunaga, D.; Matsui, T. S.; Aosaki, H.; Inoue, K.; Doostmohammadi, A.; Deguchi, S.
10.1101/2021.02.01.429065 — biophysics — Posted on 2021-02-23
733 Endosomal escape of delivered mRNA from endosomal recycling tubules visualized at the nanoscale
Paramasivam, P.; Franke, C.; Stoeter, M.; Hoijer, A.; Bartesaghi, S.; Sabirsh, A.; Lindfors, L.; Yanez Arteta, M.; Dahlen, A.; Bak, A.; Andersson, S.; Kalaidzidis, Y.; Bickle, M.; Zerial, M.
10.1101/2020.12.18.423541 — bioengineering — Posted on 2021-02-23
734 SPIN - Species by Proteome INvestigation
Ruether, P. L.; Husic, I. M.; Bangsgaard, P.; Murphy Gregersen, K.; Pantmann, P.; Carvalho, M.; Godinho, R. M.; Friedl, L.; Cascalheira, J.; Joerkov, M. L. S.; Benedetti, M.; Haws, J.; Bicho, N.; Welker, F.; Cappellini, E.; Olsen, J. V.
10.1101/2021.02.23.432520 — biochemistry — Posted on 2021-02-23
738 Rickettsia japonica in ticks infesting a wild mammal in Thailand
Hirunkanokpun, S.; Ahantarig, A.; Baimai, V.; Trinachartvanit, W.
10.1101/2021.02.23.432398 — genetics — Posted on 2021-02-23
739 Genetic effects on brain traits impact cell-type specific gene regulation during neurogenesis
Aygün, N.; Elwell, A. L.; Liang, D.; Lafferty, M. J.; Cheek, K. E.; Courtney, K. P.; Mory, J.; Hadden-Ford, E.; Krupa, O.; de la Torre-Ubieta, L.; Geschwind, D. H.; Love, M. I.; Stein, J. L.
10.1101/2020.10.21.349019 — genetics — Posted on 2021-02-23
743 Ice2 promotes ER membrane biogenesis in yeast by inhibiting the conserved lipin phosphatase complex
Papagiannidis, D.; Bircham, P. W.; Luechtenborg, C.; Ruffini, G.; Bruegger, B.; Schuck, S.
10.1101/2020.02.23.961722 — cell biology — Posted on 2021-02-23
744 Engineering of a fluorescent chemogenetic reporter with tunable color for advanced live-cell imaging
Benaissa, H.; Ounoughi, K.; Aujard, I.; Fischer, E.; Goïame, R.; Nguyen, J.; Tebo, A. G.; Li, C.; Le Saux, T.; Danglot, L.; Pietrancosta, N.; Morin, X.; Jullien, L.; Gautier, A.
10.1101/2021.01.29.428635 — molecular biology — Posted on 2021-02-23
745 Hypusinated eIF5A is required for the translation of collagen
Alepuz, P.; Barba, M.; Mena, A.; Espinoza, V.; Apostolova, N.; Costell, M.
10.1101/2021.02.23.432471 — molecular biology — Posted on 2021-02-23
747 Structure and variability of optogenetic responses identify the operating regime of cortex
Palmigiano, A.; Fumarola, F.; Mossing, D. P.; Kraynyukova, N.; Adesnik, H.; Miller, K.
10.1101/2020.11.11.378729 — neuroscience — Posted on 2021-02-23
750 Endocrine fine-tuning of daily locomotor activity patterns under non-starving conditions in Drosophila
Pauls, D.; Selcho, M.; Raederscheidt, J.; Amatobi, K. M.; Fekete, A.; Krischke, M.; Hermann-Luibl, C.; Uenal, A. G.; Ehmann, N.; Itskov, P. M.; Helfrich-Foerster, C.; Kuehnlein, R. P.; Mueller, M. J.; Wegener, C.
10.1101/2020.02.13.947556 — neuroscience — Posted on 2021-02-23
751 Parallel processing of natural images by overlapping retinal neuronal ensembles
Perez-Ortega, J. E.; Araya, J.; Ibaceta, C.; Herzog, R.; Escobar, M.-J.; Pena-Ortega, F.; Carillo-Reid, L.; Palacios, A. G.
10.1101/2021.02.22.432289 — neuroscience — Posted on 2021-02-23
753 Diffuse optical reconstructions of NIRS data using Maximum Entropy on the Mean
Cai, Z.; Machado, A.; Chowdhury, R. A.; Spilkin, A.; Vincent, T.; Aydin, U.; Pellegrino, G.; Lina, J.-M.; Grova, C.
10.1101/2021.02.22.432263 — neuroscience — Posted on 2021-02-23
754 Elucidation of Japanese pepper (Zanthoxylum piperitum De Candolle) domestication using RAD-Seq
Premarathne, M. D. G. P.; Fukutome, N.; Yamasaki, K.; Hayakawa, F.; Nagano, A. J.; Mizuno, H.; Ibaragi, N.; Nagano, Y.
10.1101/2020.12.29.424752 — plant biology — Posted on 2021-02-23
755 Impact of an oral amino acid provision on Achilles peritendinous amino acid concentrations in young and older adults
Carroll, C. C.; Couture, S.; Farino, D. O.; Patel, S. H.; Campbell, N. W.; Stout, J.; Sabbaghi, A.
10.1101/2021.02.12.430945 — physiology — Posted on 2021-02-23
756 Somatic hypomethylation of pericentromeric SST1 repeats and tetraploidization in human colorectal cancer cells
Gonzalez, B.; Navarro-Jimenez, M.; Alonso-De Gennaro, M. J.; Jansen, S. M.; Granada, I.; Perucho, M.; Alonso, S.
10.1101/2021.02.19.431645 — cancer biology — Posted on 2021-02-23
757 Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin molecular motor
Ganichkin, O.; Vancraenenbroeck, R.; Rosenblum, G.; Hofmann, H.; Mikhailov, A. S.; Daumke, O.; Noel, J. K.
10.1101/2020.09.10.289546 — biophysics — Posted on 2021-02-23
759 Activity-based urinary biomarkers of response and resistance to checkpoint blockade immunotherapy
Mac, Q. D.; Xu, C.; Bowen, J. R.; Sivakumar, A.; Phuengkham, H.; Su, F.-Y.; Stentz, S. Z.; Sim, H.; Harris, A. M.; Li, T. T.; Qiu, P.; Kwong, G. A.
10.1101/2020.12.10.420265 — bioengineering — Posted on 2021-02-23
760 Epigenetic age is accelerated in schizophrenia with age- and sex-specific effects and associated with polygenic disease risk
Ori, A. P.; Olde Loohuis, L. M.; Guintivano, J.; Hannon, E.; Dempster, E.; St. Clair, D.; Bass, N. J.; McQuillin, A.; Mill, J.; Sullivan, P. F.; Kahn, R. S.; Horvath, S.; Ophoff, R. A.
10.1101/727859 — genomics — Posted on 2021-02-23
762 Adaptation and correlated fitness responses over two time scales in Drosophila suzukii populations evolving in different environments
Olazcuaga, L.; Foucaud, J.; Gautier, M.; Deschamps, C.; Loiseau, A.; Lemenager, N.; Facon, B.; Ravigne, V.; Hufbauer, R. A.; Estoup, A.; Rode, N. O.
10.1101/749945 — evolutionary biology — Posted on 2021-02-23
764 Cardiac pathologies in mouse loss of imprinting models are due to misexpression of H19 long noncoding RNA
Pfeifer, K.; Park, K.-S.; Rahat, B.; Yu, Z.-X.; Noeker, J.; Mitra, A.; Knutsen, R.; Springer, D.; Kozel, B.
10.1101/2021.02.23.432554 — developmental biology — Posted on 2021-02-23
765 DLG2 knockout reveals neurogenic transcriptional programs underlying neuropsychiatric disorders and cognition
Sanders, B.; D'Andrea, D.; Collins, M. O.; Rees, E. E.; Steward, T. G. J.; Zhu, Y.; Chapman, G.; Legge, S. E.; Pardinas, A. F.; Harwood, A. J.; Gray, W. P.; O'Donovan, M. C.; Owen, M. J.; Errington, A. C.; Blake, D. J.; Whitcomb, D. J.; Pocklington, A. J.; Shin, E.
10.1101/2020.01.10.898676 — developmental biology — Posted on 2021-02-23
766 A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental genes partitioning in Toxoplasma
Farhat, D. C.; Bowler, M. W.; Communie, G.; PONTIER, D.; Belmudes, L.; MAS, C.; Corrao, C.; COUTE, Y.; BOUGDOUR, A.; LAGRANGE, T.; HAKIMI, M.-a.; Swale, C.
10.1101/2021.02.23.432502 — microbiology — Posted on 2021-02-23
768 Model-based inference of neutralizing antibody avidities against influenza virus
Linnik, J.; Syedbasha, M.; Hollenstein, Y.; Halter, J.; Egli, A.; Stelling, J.
10.1101/2020.10.05.326215 — immunology — Posted on 2021-02-23
770 Alpha fluctuations regulate the accrual of visual information to awareness
Torralba Cuello, M.; Drew, A.; Sabate San Jose, A.; Moris Fernandez, L.; Soto Faraco, S.
10.1101/2020.09.16.298166 — neuroscience — Posted on 2021-02-23
772 Aging predisposes B cells to malignancy by activating c-Myc and perturbing the genome and epigenome
Shindyapina, A. V.; Castro, J. P.; Barbieri, A.; Strelkova, O. S.; Paulo, J. A.; Kerepesi, C.; Petrashen, A. P.; Mariotti, M.; Meer, M.; Hu, Y.; Losyev, G.; Indzhykulian, A. A.; Gygi, S. P.; Sedivy, J. M.; Manis, J. P.; Gladyshev, V. N.
10.1101/2021.02.23.432500 — cancer biology — Posted on 2021-02-23
773 Longitudinal preclinical imaging characterization of drug delivery potential after radiotherapy in the healthy and leukemic bone marrow vascular microenvironment
Brooks, J.; Zuro, D.; Song, J. Y.; Madabushi, S. S.; Sanchez, J. F.; Kortylewski, M.; Chen, B. T.; Gupta, K.; Storme, G.; Froelich, J.; Hui, S. K.
10.1101/2021.02.23.432514 — cancer biology — Posted on 2021-02-23
776 Structure and dynamics of a cold-active esterase reveals water entropy and active site accessibility as the likely drivers for cold-adaptation
Noby, N.; Sabah Auhim, H.; Johnson, R.; Worthy, H.; Embady, a.; Saeed, H.; Hussein, A.; Rizkallah, P.; Wells, S. A.; Jones, D.
10.1101/2021.02.23.432564 — biochemistry — Posted on 2021-02-23
780 FORMATION OF LIPOFUSCIN-LIKE AUTOFLUORESCENT GRANULES IN THE RETINAL PIGMENT EPITHELIUM REQUIRES LYSOSOME DYSFUNCTION
Escrevente, C.; Falcao, A. S.; Hall, M. J.; Lopes-da-Silva, M.; Antas, P.; Mesquita, M. M.; Ferreira, I. S.; Cardoso, M. H.; Fradinho, A. C.; Futter, C. E.; Tenreiro, S.; Seabra, M. C.
10.1101/2021.02.23.432539 — cell biology — Posted on 2021-02-23
782 Inhalable Nanobody (PiN-21) prevents and treats SARS-CoV-2 infections in Syrian hamsters at ultra-low doses
Nambulli, S.; Xiang, Y.; Tilston-Lunel, N. L.; Rennick, L. J.; Sang, Z.; Klimstra, W. B.; Reed, D. S.; Crossland, N. A.; Shi, Y.; Duprex, P. W.
10.1101/2021.02.23.432569 — microbiology — Posted on 2021-02-23
785 Oral Hsp90 inhibitor, SNX-5422, attenuates SARS-CoV-2 replication and dampens inflammation in airway cells.
Goswami, R.; Russell, V. S.; Tu, J. J.; Hughes, P.; Kelly, F.; Langel, S. N.; Steppe, J.; Palmer, S. M.; Haystead, T.; Blasi, M.; Permar, S. R.
10.1101/2021.02.23.432479 — microbiology — Posted on 2021-02-23
788 Understanding LRRK2 kinase activity in preclinical models and human subjects through quantitative analysis of LRRK2 and pRab10
Wang, X.; Negrou, E.; Maloney, M. T.; Bondar, V. V.; Andrews, S. V.; Montalban, M.; Llapashtica, C.; Maciuca, R.; Nguyen, H.; Solanoy, H.; Arguello, A.; Przybyla, L.; Moerke, N. J.; Huntwork-Rodriguez, S.; Henry, A. G.
10.1101/2021.02.23.432545 — neuroscience — Posted on 2021-02-23
789 REPROGRAMMING CBX8-PRC1 FUNCTION WITH A POSITIVE ALLOSTERIC MODULATOR
Suh, J. L.; Bsteh, D.; Si, Y.; Hart, B.; Weaver, T. M.; Pribitzer, C.; Lau, R.; Soni, S.; Ogana, H.; Rectenwald, J. M.; Norris, J. L.; Cholensky, S. H.; Sagum, C.; Umana, J. D.; Li, D.; Hardy, B.; Bedford, M. T.; Mumenthaler, S. M.; Lenz, H.-J.; Kim, Y.-m.; Wang, G. G.; Pearce, K. H.; James, L.; Kireev, D. B.; Musselman, C. A.; Frye, S. V.; Bell, O.
10.1101/2021.02.23.432388 — synthetic biology — Posted on 2021-02-23
792 Metagenomic diagnosis and pathogenic network profile of SARS-CoV-2 in patients co-morbidly affected by type 2 diabetes
Al-Emran, H. M.; Rahman, M. S.; Hasan, M. S.; Alam, A. S. M. R. U.; Islam, O. K.; Anwar, A.; Jahid, I. K.; Hossain, M. A.
10.1101/2021.02.23.432535 — genomics — Posted on 2021-02-23
793 Comprehensive evaluation of ACE2 expression in female ovary by single-cell RNA-seq analysis
Kong, S.; Yan, Z.; Yuan, P.; Liu, X.; Chen, Y.; Yang, M.; Chen, W.; Song, S.; Yan, J.; Yan, L.; Qiao, J.
10.1101/2021.02.23.432460 — developmental biology — Posted on 2021-02-23
794 Single Unit Analysis and Wide-Field Imaging Reveal Alterations in Excitatory andInhibitory Neurons in Glioma
Gill, B. J. A.; Khan, F. A.; Merricks, E. M.; Goldberg, A. R.; Wu, X.; Sosunov, A. A.; Sudhakar, T.; Liou, J.-y.; Dovas, A.; McKhann, G. M.; Canoll, P.; Schevon, C.
10.1101/2021.02.23.432381 — cancer biology — Posted on 2021-02-23
797 Collagen has a unique SEC24 preference for efficient export from the endoplasmic reticulum
Lu, C.-L.; Cain, J.; Brudvig, J.; Ortmeier, S.; Boyadjiev, S.; Weimer, J. M.; Kim, J.
10.1101/2021.02.23.431880 — cell biology — Posted on 2021-02-23
798 Naegleria's mitotic spindles are built from unique tubulins and highlight core spindle features
Velle, K. B.; Trupinic, M.; Ivec, A.; Swafford, A.; Nolton, E.; Rice, L.; Tolic, I. M.; Fritz-Laylin, L. K.; Wadsworth, P.
10.1101/2021.02.23.432318 — cell biology — Posted on 2021-02-23
802 Sphingolipid Control of Fibroblast Heterogeneity Revealed by Single-Cell Lipidomics
Capolupo, L.; Khven, I.; Mazzeo, L.; Glousker, G.; Russo, F.; Paz Montoya, J.; Ho, S.; Bhandari, D. R.; Bowman, A. P.; Ellis, S.; Guiet, R.; Muthing, J.; Spengler, B.; Heeren, R. M. A.; Dotto, G.-P.; La Manno, G.; D'Angelo, G.
10.1101/2021.02.23.432420 — biochemistry — Posted on 2021-02-23
805 Deletion of Fibroblast growth factor 9 globally and in skeletal muscle results in enlarged tuberosities at sites of deltoid tendon attachments
Leek, C. C.; Soulas, J. M.; Bhattacharya, I.; Ganji, E.; Locke, R. C.; Smith, M. C.; Bhavsar, J. D.; Polson, S. W.; Ornitz, D.; Killian, M. L.
10.1101/2021.02.23.432498 — developmental biology — Posted on 2021-02-23
806 Clinical Phage Microbiology:A suggested framework and recommendations for the in-vitro matching steps ‎of phage therapy
Gelman, D.; Yerushalmy, O.; Ben-Porat, S.; Rakov, C.; Alkalay-Oren, S.; Adler, K.; Khalifa, L.; Abdalrhman, M.; Coppenhagen-Glazer, S.; Aslam, S.; Schooley, R. T.; Nir-Paz, R.; Hazan, R.
10.1101/2021.02.23.432393 — microbiology — Posted on 2021-02-23
808 Cross-sectional analysis of the microbiota of the human gut and their direct environment (exposome) in a household cohort in northern Vietnam.
Vu Thi Ngoc, B.; Ho Bich, H.; Galazzo, G.; Vu Tien Viet, D.; Oomen, M.; Nghiem Nguyen Minh, T.; Tran Huy, H.; Van Doorn, R.; Wertheim, H. F.; Penders, J.
10.1101/2021.02.23.432416 — microbiology — Posted on 2021-02-23
809 Single-cell sequencing characterizes intratumoral profile of immune cells in old mice
Zhang, C.; Lei, L.; Yang, X.; Zheng, H.; Su, Y.; Jiao, A.; Wang, X.; Liu, H.; Zou, Y.; Shi, L.; Zhou, X.; Sun, C.; Zhang, L.; Hou, Y.; Xiao, Z.; Zhang, B.
10.1101/2021.02.23.432366 — immunology — Posted on 2021-02-23
810 Resting-state theta oscillations and reward sensitivity in risk taking
Azanova, M.; Herrojo Ruiz, M.; Belianin, A. V.; Klucharev, V.; Nikulin, V. V.
10.1101/2021.02.23.432425 — neuroscience — Posted on 2021-02-23
811 Lynx1 modulates the activity of nAChRs to slow NMJ and muscle fiber degeneration during aging
Doss, S. V.; Barbat-Artigas, S.; Myers, T.; Pradhan, B. S.; Proszynski, T. J.; Robitaille, R.; Valdez, G.
10.1101/2020.05.29.123851 — neuroscience — Posted on 2021-02-23
812 Targeted comodulation supports flexible and accurate decoding in V1
Haimerl, C.; Ruff, D. A.; Cohen, M. R.; Savin, C.; Simoncelli, E. P.
10.1101/2021.02.23.432351 — neuroscience — Posted on 2021-02-23
814 Circadian Transcriptomic and Epigenomic Remodeling in Response to Lipid Overload and Human Obesity
Sardon Puig, L.; Altintas, A.; Casani, S.; Gabriel, B. M.; Barres, R.; Conesa, A.; Chibalin, A. V.; Naslund, E.; Krook, A.; Pillon, N. J.; Zierath, J. R.
10.1101/2021.02.23.432336 — physiology — Posted on 2021-02-23
816 Structural and functional characterization of SARS-CoV-2 RBD domains produced in mammalian cells
Gstoettner, C.; Zhang, T.; Resemann, A.; Ruben, S.; Pengelley, S.; Suckau, D.; Welsink, T.; Wuhrer, M.; Dominguez-Vega, E.
10.1101/2021.02.23.432424 — biochemistry — Posted on 2021-02-23
818 Chromatin reader Dido3 regulates the genetic network of B cell differentiation
Gutierrez del Burgo, F.; Pons, T.; Vazquez de Luis, E.; Martinez-A, C.; Villares, R.
10.1101/2021.02.23.432411 — molecular biology — Posted on 2021-02-23
819 A monocyte/dendritic cell molecular signature of SARS-CoV2-related multisystem inflammatory syndrome in children (MIS-C) with severe myocarditis
de Cevins, C.; Luka, M.; Smith, N.; Meynier, S.; Magerus, A.; Carbone, F.; Garcia Paredes, V.; Barnabei, L.; Batignes, M.; Boulle, A.; Stolzenberg, M.-C.; Perot, B. P.; Charbit, B.; Fali, T.; Pirabarakan, V.; Sorin, B.; Riller, Q.; Abdessalem, G.; Beretta, M.; Grzelak, L.; Goncalves, P.; Di Santo, J. P.; Mouquet, H.; Schwartz, O.; Zarhrate, M.; Parisot, M.; Bole-Feysot, C.; Masson, C.; Cagnard, N.; Corneau, A.; Bruneau, C.; Zhang, S.-Y.; Casanova, J.-L.; Bader Meunier, B.; Haroche, J.; Melki, I.; Lorrot, M.; Oualha, M.; Moulin, F.; Bonnet, D.; Belhadjer, Z.; Leruez, M.; Allali, S.; Gras Leguen
10.1101/2021.02.23.432486 — immunology — Posted on 2021-02-23
821 Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection.
Ma, L.; Sahu, S. K.; Cano, M.; Kuppuswamy, V.; Bajwa, J.; McPhatter, J.; Pine, A. B.; Meizlish, M. M.; Goshua, G.; Chang, C. H.; Zhang, H.; Price, C.; Bahel, P.; Rinder, H. M.; Lei, T.; Day, A.; Reynolds, D.; Wu, X.; Schriefer, R.; Rauseo, A. M.; Goss, C. W.; O'Halloran, J. A.; Presti, R. M.; Kim, A. H.; Gelman, A. E.; Dela Cruz, C. S.; Lee, A. I.; Mudd, P. A.; Chun, H. J.; Atkinson, J. P.; Kulkarni, H. S.
10.1101/2021.02.22.432177 — immunology — Posted on 2021-02-23
822 SARS-CoV-2 causes brain inflammation and induces Lewy body formation in macaques
Philippens, I. H. C. H. M.; Boszormenyi, K. P.; Wubben, J. A.; Fagrouch, Z. C.; van Driel, N.; Mayenburg, A. Q.; Lozovagia, D.; Roos, E.; Schurink, B.; Bugiani, M.; Bontrop, R. E.; Middeldorp, J.; Bogers, W. M.; de Geus-Oei, L.-F.; Langermans, J. A. M.; Stammes, M. A.; Verstrepen, B. E.; Verschoor, E. J.
10.1101/2021.02.23.432474 — neuroscience — Posted on 2021-02-23
823 Human basigin (CD147) does not directly interact with SARS-CoV-2 spike glycoprotein
Ragotte, R. J.; Pulido, D.; Donnellan, F. R.; Gorini, G.; Davies, H.; Brun, J.; King, L. D.; Skinner, K.; Draper, S. J.
10.1101/2021.02.22.432402 — biochemistry — Posted on 2021-02-23
824 Histone H2Bub1 deubiquitylation is essential for mouse development, but does not regulate global RNA polymerase II transcription
Wang, F.; El-Saafin, F.; Ye, T.; Stierle, M.; Negroni, L.; Durik, M.; Fischer, V.; Devys, D.; Vincent, S. D.; Tora, L.
10.1101/2021.02.23.432458 — molecular biology — Posted on 2021-02-23
826 A preliminary assessment of allostatic load in male mantled howler monkeys
Dias, P. A. D.; Coyohua Fuentes, A.; Chavira Ramirez, D. R.; Canales Espinosa, D.; Rangel Negrin, A.
10.1101/2021.02.22.432350 — zoology — Posted on 2021-02-23
827 Systems approaches identify the consequences ofmonosomy in somatic human cells
Chunduri, N. K.; Menges, P.; Gotsmann, V. L.; Zhang, X.; Mardin, B. R.; Buccitelli, C.; Korbel, J. O.; Willmund, F.; Kschischo, M.; Raeschle, M.; Storchova, Z.
10.1101/2021.02.22.432226 — systems biology — Posted on 2021-02-23
828 macroH2A2 shapes chromatin accessibility at enhancer elements in glioblastoma to modulate a targetable self-renewal epigenetic network
Nikolic, A.; Bobyn, A.; Maule, F.; Ellestad, K.; Lun, X.; Johnston, M.; Gafuik, C.; Zemp, F.; Ninkovic, N.; Marhon, S.; Mehdipour, P.; Shen, Y.; Berger, D.; Brownsey, D.; Dirks, P.; Derksen, D.; Jones, S.; de Carvalho, D.; Senger, D.; Chan, J.; Mahoney, D.; Gallo, M.
10.1101/2021.02.23.432465 — cancer biology — Posted on 2021-02-23
829 Multi-fluorescence high-resolution episcopic microscopy (MF-HREM) for three dimensional imaging of adult murine organs
Walsh, C.; Holroyd, N.; Finnerty, E.; Ryan, S. G.; Sweeney, P. W.; Shipley, R. J.; Walker-Samuel, S.
10.1101/2020.04.03.023978 — biophysics — Posted on 2021-02-23
831 Visualizing multi-protein patterns at the synapse of neuronal tissue with DNA-assisted single-molecule localization microscopy
Narayanasamy, K. K.; Stojic, A.; Li, Y.; Sass, S.; Hesse, M.; Deussner-Helfmann, N. S.; Dietz, M. S.; Klevanski, M.; Kuner, T.; Heilemann, M.
10.1101/2021.02.23.432306 — biophysics — Posted on 2021-02-23
838 Solving the Sample Size Problem for Resource Selection Analysis
Street, G. M.; Potts, J. R.; Borger, L.; Beasley, J.; Demarais, S.; Fryxell, J. M.; McLoughlin, P.; Monteith, K.; Prokopenko, C.; Ribeiro, M.; Rodgers, A.; Strickland, B.; Van Beest, F.; Bernasconi, D.; Beumer, L.; Dharmarajan, G.; Dwinnell, S.; Keiter, D.; Keuroghlian, A.; Newediuk, L.; Oshima, J.; Rhodes, O.; Schlichting, P.; Schmidt, N.; Vander Wal, E.
10.1101/2021.02.22.432319 — ecology — Posted on 2021-02-23
841 Chelator sensing and lipopeptide interplay mediates molecular interspecies interactions between soil bacilli and pseudomonads
Andric, S.; Meyer, T.; Rigolet, A.; Arguelles Arias, A.; Steels, S.; Hoff, G.; Hofte, M.; De Mot, R.; McCann, A.; De Pauw, E.; Ongena, M.
10.1101/2021.02.22.432387 — microbiology — Posted on 2021-02-23
846 Apple ripening is controlled by a NAC transcription factor
Migicovsky, Z.; Yeats, T. H.; Watts, S.; Song, J.; Forney, C. F.; Burgher-MacLellan, K.; Somers, D. J.; Gong, Y.; Zhang, Z.; Vrebalov, J.; Giovannoni, J. G.; Rose, J. K. C.; Myles, S.
10.1101/708040 — plant biology — Posted on 2021-02-23
853 Chemoproteomics Enabled Discovery of Selective Probes for NuA4 Factor BRD8
Remillard, D.; Savage, N. A.; Kedves, A. T.; Paulk, J.; Chen, X.; Garcia, F. J.; Romanowski, M. J.; Horton, P. A.; Murphy, J.; Schirle, M.; Harrington, E. M.; Maxwell, M. B.; Pham, H. T.; Maksimovic, I.; Thomas, J. R.; Forrester, W. C.
10.1101/2021.02.22.432362 — biochemistry — Posted on 2021-02-23
854 Seven amino acid types suffice to reconstruct the core fold of RNA polymerase
Yagi, S.; Padhi, A. K.; Vucinic, J.; Barbe, S.; Schiex, T.; Nakagawa, R.; Simoncini, D.; Zhang, K. Y. J.; Tagami, S.
10.1101/2021.02.22.432383 — biochemistry — Posted on 2021-02-23
858 High-order interactions maintain or enhance structural robustness of a coffee agroecosystem network
Gonzalez Gonzalez, C.; Mora Van Cauwelaert, E.; Boyer, D.; Perfecto, I.; Vandermeer, J.; Benitez Keinrad, M.
10.1101/2021.02.22.432328 — ecology — Posted on 2021-02-23
863 improv: A flexible software platform for adaptive neuroscience experiments
Draelos, A.; Nikitchenko, M.; Sriworarat, C.; Sprague, D.; Loring, M. D.; Pnevmatikakis, E.; Giovannucci, A.; Naumann, E. A.; Pearson, J. M.
10.1101/2021.02.22.432006 — neuroscience — Posted on 2021-02-23
864 Hierarchical cross-scale analysis identifies parallel ventral striatal networks coding for dynamic and stabilized olfactory reward predictions
Winkelmeier, L.; Filosa, C.; Scheller, M.; Hartig, R.; Sack, M.; Becker, R.; Wolf, D.; Reinwald, J.; Gerchen, M. F.; Sartorius, A.; Meyer-Lindenberg, A.; Weber-Fahr, W.; Clemm von Hohenberg, C.; Russo, E.; Kelsch, W.
10.1101/2021.02.22.432268 — neuroscience — Posted on 2021-02-23
865 Suppression of alpha-band power underlies exogenous attention to emotional distractors
Arana, L.; Melcon, M.; Kessel, D.; Hoyos, S.; Albert, J.; Carretie, L.; Capilla, A.
10.1101/2021.02.22.432307 — neuroscience — Posted on 2021-02-23
866 Diffuse optical reconstructions of NIRS data using Maximum Entropy on the Mean
Cai, Z.; Machado, A.; Chowdhury, R. A.; Spilkin, A.; Vincent, T.; Aydin, U.; Pellegrino, G.; Lina, J.-M.; Grova, C.
10.1101/2021.02.22.432263 — neuroscience — Posted on 2021-02-23
867 Parallel processing of natural images by overlapping retinal neuronal ensembles
Perez-Ortega, J. E.; Araya, J.; Ibaceta, C.; Herzog, R.; Escobar, M.-J.; Pena-Ortega, F.; Carillo-Reid, L.; Palacios, A. G.
10.1101/2021.02.22.432289 — neuroscience — Posted on 2021-02-23
869 Partitioning variability in animal behavioral videos using semi-supervised variational autoencoders
Whiteway, M. R.; Biderman, D.; Friedman, Y.; Dipoppa, M.; Buchanan, E. K.; Wu, A.; Zhou, J.; Noel, J.-P. R.; The International Brain Lab, ; Cunningham, J. P.; Paninski, L.
10.1101/2021.02.22.432309 — neuroscience — Posted on 2021-02-23
874 Rewritable Two-Dimensional DNA-Based Data Storage with Machine Learning Reconstruction
Pan, C.; Tabatabaei, K.; Tabatabaei Yazdi, S. M. H.; Hernandez, A. G.; Schroeder, C. M.; Milenkovic, O.
10.1101/2021.02.22.432304 — synthetic biology — Posted on 2021-02-23
875 Clinically-Driven Design of Synthetic Gene Regulatory Programs in Human Cells
Israni, D. V.; LI, H.; Gagnon, K. A.; Sander, J. D.; Roybal, K. T.; Joung, J. K.; Wong, W.; Khalil, A. S.
10.1101/2021.02.22.432371 — synthetic biology — Posted on 2021-02-23
891 The G2-phase enriched lncRNA SNHG26 is necessary for proper cell cycle progression and proliferation
Samdal, H.; Hegre, S. A.; Chawla, K.; Liabakk, N.-B.; Aas, P. A.; Sporsheim, B.; Saetrom, P.
10.1101/2021.02.22.432245 — molecular biology — Posted on 2021-02-23
892 Epigenetic rewriting at centromeric DNA repeats leads to increased chromatin accessibility and chromosomal instability
Decombe, S.; Loll, F.; Caccianini, L.; Affannoukoue, K.; Izeddin, I.; Mozziconacci, J.; Escude, C.; Lopes, J.
10.1101/2021.02.22.432244 — molecular biology — Posted on 2021-02-23
893 Expression of CD49f defines subsets of human regulatory T cells with divergent transcriptional landscape and function that correlate with ulcerative colitis disease activity
Weerakoon, H.; Straube, J.; Lineburg, K.; Cooper, L.; Lane, S.; Smith, C.; Alabbas, S.; Begun, J.; Miles, J. J.; Hill, M. M.; Lepletier, A.
10.1101/2021.02.22.432185 — immunology — Posted on 2021-02-23
894 Human immunodeficiency reveals GIMAP5 as lymphocyte-specific regulator of senescence
Park, A. Y.; Leney-Greene, M.; Lynberg, M.; Xu, X.; Zheng, L.; Zhang, Y.; Matthews, H.; Chao, B.; Morawski, A.; Jiang, P.; Aluri, J.; Aydine, E. K.; Kiykim, A.; Pascall, J.; Barlan, I.; Sari, S.; Butcher, G.; Rao, V. K.; Lifton, R. P.; Baris, S.; Ozen, A.; Vilarinho, S.; Su, H.; Lenardo, M. J.
10.1101/2021.02.22.432146 — immunology — Posted on 2021-02-23
895 pyControl: Open source, Python based, hardware and software for controlling behavioural neuroscience experiments.
Akam, T.; Lustig, A.; Rowland, J.; Kapanaiah, S. K. T.; Esteve-Agraz, J.; Panniello, M.; Marquez, C.; Kohl, M.; Kätzel, D.; Costa, R. M.; Walton, M. E.
10.1101/2021.02.22.432227 — neuroscience — Posted on 2021-02-23
896 Loss of FAS1 function reveals rescue of an aberrant intra-S-phase checkpoint by the G2/M checkpoint regulator SOG1
Eekhout, T.; Dvorackova, M.; Pedroza Garcia, J.; Nespor Dadejova, M.; Kalhorzadeh, P.; Van den Daele, H.; Vercauteren, I.; Fajkus, J.; De Veylder, L.
10.1101/2021.02.22.432330 — plant biology — Posted on 2021-02-23
897 TPX2 Amplification-Driven Aberrant Mitosis in Long-Term Cultured Human Embryonic Stem Cells
Jeong, H.-C.; Go, Y.-H.; Shin, J.-G.; Kim, Y.-J.; Cho, M.-G.; Gwon, D.; Cheong, H. S.; Lee, H.; Lee, J.-H.; Jang, C.-Y.; Shin, H. D.; Cha, H.-J.
10.1101/2021.02.22.432205 — cell biology — Posted on 2021-02-23
901 Cubam receptor-mediated endocytosis in hindgut-derived pseudoplacenta of a viviparous teleost Xenotoca eiseni
Iida, A.; Sano, K.; Inokuchi, M.; Nomura, J.; Suzuki, T.; Kuriki, M.; Sogabe, M.; Susaki, D.; Tonosaki, K.; Kinoshita, T.; Hondo, E.
10.1101/2021.02.01.429082 — zoology — Posted on 2021-02-23
902 Mitogenomic Phylogeny of Callithrix with Special Focus on Human Transferred Taxa
Malukiewicz, J.; Cartwright, R. A.; Curi, N. H.; Dergam, J. A.; Igayara, C. S.; Moreira, S. B.; Molina, C. V.; Nicola, P. A.; Noll, A.; Passamani, M.; Pereira, L. C.; Pissinatti, A.; Ruiz-Miranda, C. R.; Silva, D. L.; Stone, A. C.; Zinner, D.; Roos, C.
10.1101/2020.08.12.247692 — genomics — Posted on 2021-02-23
903 TGF-beta promotes microtube formation in glioblastoma through Thrombospondin 1
Joseph, J. V.; Magaut, C. R.; Storevik, S.; Geraldo, L. H.; Mathivet, T.; Latif, A. M.; Rudewicz, J.; Guyon, J.; Gambaretti, M.; Haukas, F.; Trones, A.; Ystaas, L. A. R.; Hossain, J. A.; Ninzima, S.; Zhou, W.; Tomar, T.; Klink, B.; Rane, L.; Irving, B. K.; Marrison, J.; O Toole, P.; Wurdak, H.; Wang, J.; Di, Z.; Winkler, F.; Kruyt, F. A.; Bikfalvi, A.; Bjerkvig, R.; Daubon, T.; Miletic, H.
10.1101/2021.02.22.431443 — cancer biology — Posted on 2021-02-22
907 A combined EM and proteomic analysis places HIV-1 Vpu at the crossroads of retromer and ESCRT complexes: PTPN23 is a Vpu-cofactor
Stoneham, C. A.; Langer, S.; De Jesus, P.; Wozniak, J.; Lapek, J.; Deerinck, T.; Thor, A.; Pache, L.; Chanda, S.; Gonzalez, D.; Ellisman, M.; Guatelli, J.
10.1101/2021.02.22.432252 — microbiology — Posted on 2021-02-22
908 Trends in community- and nosocomial-acquired infections of carbapenem resistant Enterobacteriaceae (CRE), carbapenemase producing Enterobacteriaceae (CPE) and vancomycin resistant Enterococcus (VRE): a 10-year prospective observational study.
Ubillus Arriola, G. M.; Araujo Banchon, W. E.; Patino Gabriel, L.; Kolevic, L.; Quispe Manco, M. d. C. M.; Olivo Lopez, J. M.; Barrientos Achata, A. M.; Bouzid, D.; Revilla Velasquez, M. E.; Casalino, E.
10.1101/2021.02.22.432249 — microbiology — Posted on 2021-02-22
909 A massive 7T fMRI dataset to bridge cognitive and computational neuroscience
Allen, E. J.; St-Yves, G.; Wu, Y.; Breedlove, J. L.; Dowdle, L. T.; Caron, B.; Pestilli, F.; Charest, I.; Hutchinson, J. B.; Naselaris, T.; Kay, K.
10.1101/2021.02.22.432340 — neuroscience — Posted on 2021-02-22
911 Planum Temporale grey matter volume asymmetries in new-born monkeys (Papio anubis)
Becker, Y.; Phelipon, R.; Sein, J.; Velly, L.; Renaud, L.; Meguerditchian, A.
10.1101/2021.02.22.432274 — neuroscience — Posted on 2021-02-22
912 The Optimum Cut-off Value of the Nelwan Score to Diagnose Typhoid Fever in Adults
Nelwan, E.; Paramita, L. P. L.; Sinto, R.; Hosea, F. N.; Nugroho, P.; Pohan, H.
10.1101/2021.02.22.432239 — pathology — Posted on 2021-02-22
913 Genetic diversity and population history of eight Italian beef cattle breeds using measures of autozygosity
Fabbri, M. C.; Dadousis, C.; Tiezzi, F.; Maltecca, C.; Lozada-Soto, E.; Biffani, S.; Bozzi, R.
10.1101/2021.02.22.432240 — genomics — Posted on 2021-02-22
915 Mutational sources of trans-regulatory variation affecting gene expression in Saccharomyces cerevisiae
Duveau, F.; Vande Zande, P.; Metzger, B. P. H.; Diaz, C. J.; Walker, E. A.; Tryban, S.; Siddiq, M. A.; Yang, B.; Wittkopp, P. J.
10.1101/2021.02.22.432283 — genetics — Posted on 2021-02-22
916 Genetic mapping and identification of a QTL determining tolerance to freezing stress in Fragaria vesca L.
Davik, J.; Wilson, R. C.; Njah, R. G.; Grini, P. E.; Randall, S. K.; Alsheikh, M. K.; Sargent, D. J.
10.1101/2021.02.22.432243 — genetics — Posted on 2021-02-22
917 RELATIONSHIP BETWEEN PARENTAL AGE AND SEVERITY OF OROFACIAL CLEFTS
Adamson, O. O.; Oladugba, A.; Alade, A.; Awotoye, W.; Busch, T.; Li, M.; Fashina, A.; Olotu, J.; Sule, V.; James, O.; Ogunlewe, M.; Adeyemo, W.; Butali, A.
10.1101/2021.02.22.432246 — genetics — Posted on 2021-02-22
919 The last battle of Anne of Brittany: solving mass grave through an interdisciplinary approach (paleopathology, anthropobiology, history, multiple isotopes and radiocarbon dating)
Colleter, R.; Bataille, C.; Milano, S.; Dabernat, H.; Trost, M.; Marchal, M.; Guilbeau-Frugier, C.; Pichot, D.; Hamon, P.; Labaune-Jean, F.; Jean, S.; Le Cloirec, G.; Steinbrenner, S.; Duchesne, S.; Telmon, N.; Crubezy, E.; Jaouen, K.
10.1101/2021.02.22.432237 — ecology — Posted on 2021-02-22
922 Oncofusion-driven de novo enhancer assembly promotes malignancy in Ewing sarcoma via aberrant expression of the stereociliary protein LOXHD1
asangani, i. a.; Deng, Q.; Natesan, R.; Cidre-Aranaz, F.; Arif, S.; Liu, Y.; Rasool, R.; Wang, P.; Cramer, Z.; Chou, M.; Kumar-Sinha, C.; Weber, K.; Eisinger-Mathason, K.; Grillet, N.; Grunewald, T. G. P.
10.1101/2021.02.22.432287 — cancer biology — Posted on 2021-02-22
925 Isolation and characterisation of bacteriophages with activity against invasive non-typhoidal Salmonella causing bloodstream infection in Malawi
Rodwell, E. V.; Wenner, N.; Pulford, C. V.; Cai, Y.; Bowers-Barnard, A.; Beckett, A.; Rigby, J.; Picton, D. M.; Blower, T. R.; Feasey, N. A.; Hinton, J. C. D.; Perez-Sepulveda, B. M.
10.1101/2021.02.18.431836 — microbiology — Posted on 2021-02-22
928 Astrocyte-derived TNF and glutamate critically modulate microglia reactivity by methamphetamine
Canedo, T.; Portugal, C. C.; Socodato, R.; Bravo, J.; Almeida, T. O.; Magalhaes, J. D.; Guerra-Gomes, S.; Oliveira, J. F.; Sousa, N.; Magalhaes, A.; Relvas, J. B.; Summavielle, T.
10.1101/2021.02.22.432170 — neuroscience — Posted on 2021-02-22
929 Grapevine rootstocks affect growth-related scion phenotypes
Migicovsky, Z.; Cousins, P.; Jordan, L. M.; Myles, S.; Striegler, R. K.; Verdegaal, P.; Chitwood, D. H.
10.1101/864850 — plant biology — Posted on 2021-02-22
931 Flanker: a tool for comparative genomics of gene flanking regions
Matlock, W.; Lipworth, S.; Constantinides, B.; Peto, T. E. A.; Walker, A. S.; Crook, D. W.; Hopkins, S.; Shaw, L. P.; Stoesser, N.
10.1101/2021.02.22.432255 — bioinformatics — Posted on 2021-02-22
932 Stress-induced tyrosine phosphorylation of RtcB modulates IRE1 activity and signaling outputs.
Papaioannou, A.; Centonze, F. G.; Metais, A.; Maurel, M.; Negroni, L.; Gonzales-Quiroz, M.; Zare Golchesmeh, E.; Blondel, A.; Koong, A. C.; Hetz, C.; Pedeux, R.; Tremblay, M. L.; Eriksson, L. A.; chevet, e.
10.1101/2020.03.02.972950 — biochemistry — Posted on 2021-02-22
933 Genome and transcriptome of a pathogenic yeast, Candida nivariensis
Fan, Y.; Gale, A.; Bailey, A.; Barnes, K.; Colotti, K.; Mass, M.; Morina, L. B.; Robertson, B.; Schwab, R.; Tselepidakis, N.; Timp, W.
10.1101/2021.01.27.428461 — genomics — Posted on 2021-02-22
937 Establishment of Culex modestus in Belgium and a glance into the virome of Belgian mosquito species
Wang, L.; Rosales Rosas, A. L.; De Coninck, L.; Shi, C.; Bouckaert, J.; Matthijnssens, J.; Delang, L.
10.1101/2020.11.27.401372 — microbiology — Posted on 2021-02-22
938 A novel DNA-binding protein regulates sexual differentiation in malaria parasites and is essential for transmission.
Campelo Morillo, R.; Tong, X.; Xie, W.; Lenz, T.; Batugedara, G.; Tabassum, N.; Orchard, L. M.; Daher, W.; Patel, D.; Noble, W. S.; Llinas, M.; Le Roch, K. G.; Kafsack, B. F. C.
10.1101/2020.10.26.352583 — microbiology — Posted on 2021-02-22
939 Glyphosate Inhibits Melanization and Increases Susceptibility to Infection in Insects
Smith, D. F. Q.; Camacho, E.; Thakur, R.; Barron, A. J.; Dong, Y.; Dimopoulos, G.; Broderick, N. A.; Casadevall, A.
10.1101/2020.05.20.105353 — microbiology — Posted on 2021-02-22
940 Sialic acid ligands of CD28 block co-stimulation of T cells
Edgar, L. J.; Thompson, A. J.; Vartabedian, V. F.; Kikuchi, C.; Woehl, J. L.; Teijaro, J. R.; Paulson, J. C.
10.1101/2021.02.22.432333 — immunology — Posted on 2021-02-22
943 Pharmacokinetics of Orally Administered GS-441524 in Dogs
Yan, V. C.; Khadka, S.; Arthur, K.; Pham, C.-D.; Yan, M. J.; Yan, A. J.; Ackroyd, J. J.; Georgiou, D. K.; Muller, F. L.
10.1101/2021.02.04.429674 — pharmacology and toxicology — Posted on 2021-02-22
944 Human immunocompetent Organs-on-Chips platforms allow safety profiling of tumor-targeted T-cell bispecific antibodies
Cabon, L.; Petropolis, D.; Tien-Street, W.; Ng, P. R.; Grant, H. S.; Karalis, K.; Hamilton, G. A.; Sam, J.; Weinzierl, T.; Fauti, T.; Freimoser-Grundschober, A.; Eckmann, J.; Hage, C.; Geiger, M.; Micallef, V.; Gerard, R.; Bscheider, M.; Breous-Nystrom, E.; Schneider, A.; Giusti, A. M.; Bertinetti-Lapatki, C.; Roth, A. B.; Singer, T.; Kanellias, M.; Manatakis, D. V.; Moisan, A.; Bruenker, P.; Klein, C.; Bacac, M.; Gjorevski, N.; Belgur, C.; Kerns, S. J.; Barrile, R.
10.1101/2021.02.22.432308 — cancer biology — Posted on 2021-02-22
945 The novel, recurrent mutation in the TOP2A gene results in the enhanced topoisomerase activity and transcription deregulation in glioblastoma
Gielniewski, B.; Poleszak, K.; Roura, A.-J.; Szadkowska, P.; Krol, S. K.; Guzik, R.; Wiechecka, P.; Maleszewska, M.; Kaza, B.; Marchel, A.; Czernicki, T.; Koziarski, A.; Zielinski, G.; Styk, A.; Kawecki, M.; Szczylik, C.; Czepko, R.; Banach, M.; Kaspera, W.; Szopa, W.; Bujko, M.; Czapski, B.; Zabek, M.; Izycka-Swieszewska, E.; Kloc, W.; Nauman, P.; Cieslewicz, J.; Wojtas, B.; Kaminska, B.
10.1101/2020.06.17.158477 — cancer biology — Posted on 2021-02-22
946 An R Package for Divergence Analysis of Omics Data
Dinalankara, W.; Ke, Q.; Geman, D.; Marchionni, L.
10.1101/720391 — bioinformatics — Posted on 2021-02-22
948 Protein yield is tunable by synonymous codon changes of translation initiation sites
Bhandari, B. K.; Lim, C. S.; Remus, D. M.; Chen, A.; van Dolleweerd, C.; Gardner, P. P.
10.1101/726752 — bioinformatics — Posted on 2021-02-22
949 A comprehensive and centralized database for exploring omics data in Autoimmune Diseases
Martorell-Marugan, J.; Lopez-Dominguez, R.; Garcia-Moreno, A.; Toro-Dominguez, D.; Villatoro-Garcia, J. A.; Barturen, G.; Martin-Gomez, A.; Troule, K.; Gomez-Lopez, G.; Al-Shahrour, F.; Gonzalez-Rumayor, V.; Pena-Chilet, M.; Dopazo, J.; Saez-Rodriguez, J.; Alarcon-Riquelme, M. E.; Carmona-Saez, P.
10.1101/2020.06.10.144972 — bioinformatics — Posted on 2021-02-22
950 Random access DNA memory in a scalable, archival file storage system
Banal, J. L.; Shepherd, T. R.; Berleant, J. D.; Huang, H.; Reyes, M.; Ackerman, C. M.; Blainey, P.; Bathe, M.
10.1101/2020.02.05.936369 — bioengineering — Posted on 2021-02-22
958 Catabolism of lysosome-related organelles in color-changing spiders supports intracellular turnover of pigments
Figon, F.; Hurbain, I.; Heiligenstein, X.; Trepout, S.; Medjoubi, K.; Somogyi, A.; Delevoye, C.; Raposo, G.; Casas, J.
10.1101/2021.02.22.432296 — cell biology — Posted on 2021-02-22
960 Modeling SARS-CoV-2 infection and its individual differences with ACE2-expressing human iPS cells
Sano, E.; Sakamoto, A.; Mimura, N.; Hirabayashi, A.; Muramoto, Y.; Noda, T.; Yamamoto, T.; Takayama, K.
10.1101/2021.02.22.432218 — cell biology — Posted on 2021-02-22
961 Transmission of pre-XDR and XDR-TB in the Mumbai Metropolitan Region, India
Dreyer, V.; Mandal, A.; Dev, P.; Merker, M.; Barilar, I.; Utpatel, C.; Nilgiriwala, K.; Rodrigues, C.; Crook, D. W.; CRyPTIC Consortium, ; Mistry, N. S.; Niemann, S.
10.1101/2021.02.02.429364 — molecular biology — Posted on 2021-02-22
962 Surfactin stimulated by pectin molecular patterns and root exudates acts as a key driver of Bacillus-plant mutualistic interaction
Hoff, G.; Arguelles Arias, A.; Boubsi, F.; Prsic, J.; Meyer, T.; Ibrahim, H. M. M.; Steels, S.; Luzuriaga, P.; Legras, A.; Franzil, L.; Lequart, M.; Rayon, C.; Osorio, V.; de Pauw, E.; Lara, Y.; Deboever, E.; de Coninck, B.; Jacques, P.; Deleu, M.; Petit, E.; Van Wuytswinkel, O.; Ongena, M.
10.1101/2021.02.22.432335 — microbiology — Posted on 2021-02-22
964 Monitoring oxidative inflammatory processes in live cells and tissue with Hypocrates, a genetically encoded biosensor for hypochlorite
Kostyuk, A.; Tossounian, M.-A.; Panova, A.; Thauvin, M.; Wahni, K.; Van Molle, I.; Raevskii, R.; Baranov, M.; Vriz, S.; Messens, J.; Bilan, D.; Belousov, V.
10.1101/2021.02.22.432222 — immunology — Posted on 2021-02-22
965 Bovine neutrophils release extracellular traps and cooperate with macrophages in Mycobacterium avium subsp. paratuberculosis clearance in vitro
Ladero-Aunon, I.; Molina, E.; Holder, A.; Kolakowski, J.; Harris, H.; Urkitza, A.; Anguita, J.; Werling, D.; Elguezabal, N.
10.1101/2020.12.30.424791 — immunology — Posted on 2021-02-22
967 Sterile Inflammation Alters Neutrophil Kinetics in Mice
Singh, A.; Jothiprakasam, T.; Raghavan, J. V.; Jhunjhunwala, S.
10.1101/2021.02.12.430891 — immunology — Posted on 2021-02-22
968 Heterogeneity and excitability of BRAFV600E-induced tumors is determined by PI3K/mTOR-signaling state and Trp53-loss
Cases-Cunillera, S.; van Loo, K. M. J.; Pitsch, J.; Quatraccioni, A.; Sivalingam, S.; Salomoni, P.; Dietrich, D.; Schoch, S.; Becker, A. J.
10.1101/2021.02.22.432030 — neuroscience — Posted on 2021-02-22
969 Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy
Wang, C.; Fan, L.; Zhan, L.; Kodama, L.; Liu, B.; Chin, M. Y.; Li, Y.; Le, D.; Zhou, Y.; Condello, C.; Grinberg, L. T.; Seeley, W. W.; Miller, B. L.; Mok, S.-A.; Gestwicki, J. E.; Gan, L.
10.1101/2021.02.22.432272 — neuroscience — Posted on 2021-02-22
970 A compact spatial map in V2 visual cortex
Long, X.; Deng, B.; Cai, J.; Chen, Z. S.; Zhang, S.-J.
10.1101/2021.02.11.430687 — neuroscience — Posted on 2021-02-22
976 Synergy of chemotherapy and macrophage depletion leads to T cell memory activation and durable triple negative breast cancer regression
Singh, S.; Lee, N.; Bado, I.; Hamor, C.; Zhang, L.; Aguirre, S.; Hu, J.; Shen, Y.; Xu, Y.; Gao, Y.; Pedroza, D.; Zhan, N.; Chen, S.-H.; Wan, Y.-W.; Liu, Z.; Chang, J.; Hollern, D.; Perou, C.; Zhang, X.; Rosen, J. M.
10.1101/2021.02.22.432300 — cancer biology — Posted on 2021-02-22
978 Tetrameric UvrD helicase is located at the E. coli replisome due to frequent replication blocks
Wollman, A. J.; Syeda, A.; Leech, A.; Guy, C.; McGlynn, P.; Hawkins, M.; Leake, M. C.
10.1101/2021.02.22.432310 — biophysics — Posted on 2021-02-22
981 PharmaNet: Pharmaceutical discovery with deep recurrent neural networks.
Ruiz Puentes, P.; Valderrama, N.; Gonzalez, C.; Daza, L.; Munoz-Camargo, C.; Cruz, J. C.; Arbelaez, P.
10.1101/2020.10.21.348441 — bioinformatics — Posted on 2021-02-22
985 The role of interspecies recombinations in the evolution of antibiotic resistant pneumococci
D'Aeth, J. C.; van der Linden, M. P. G.; McGee, L.; De Lencastre, H. C.; Turner, P.; Song, J.-H.; Lo, S. W.; Gladstone, R. A.; Sá-Leão, R.; Ko, K. S.; Hanage, W. P.; Beall, B.; Bentley, S. D.; Croucher, N. J.; The GPS Consortium,
10.1101/2021.02.22.432219 — genomics — Posted on 2021-02-22
988 A Comprehensive Phylogenomic Platform for Exploring the Angiosperm Tree of Life
Baker, W. J.; Bailey, P.; Barber, V.; Barker, A.; Bellot, S.; Bishop, D.; Botigue, L. R.; Brewer, G.; Carruthers, T.; Clarkson, J. J.; Cook, J.; Cowan, R. S.; Dodsworth, S.; Epitawalage, N.; Francoso, E.; Gallego, B.; Johnson, M.; Kim, J. T.; Leempoel, K.; Maurin, O.; McGinnie, C.; Pokorny, L.; Roy, S.; Stone, M.; Toledo, E.; Wickett, N. J.; Zuntini, A. R.; Eiserhardt, W. L.; Kersey, P. J.; Leitch, I. J.; Forest, F.
10.1101/2021.02.22.431589 — evolutionary biology — Posted on 2021-02-22
989 Sex-specific body mass ageing trajectories in adult Asian elephants
Lalande, L. D.; Lummaa, V.; Aung, H. H.; Htut, W.; Nyein, U. K.; Berger, V.; Briga, M.
10.1101/2020.12.17.423208 — evolutionary biology — Posted on 2021-02-22
990 A G protein-coupled receptor is required in cartilaginous and dense connective tissues to maintain spine alignment
Liu, Z.; Hussien, A. A.; Wang, Y.; Heckman, T.; Gonzalez, R.; Karner, C. M.; Snedeker, J. G.; GRAY, R.
10.1101/2021.02.22.432353 — developmental biology — Posted on 2021-02-22
991 Atg39 selectively captures inner nuclear membrane into lumenal vesicles for delivery to the autophagosome
Chandra, S.; Mannino, P. J.; Thaller, D. J.; Ader, N. R.; King, M. C.; Melia, T.; Lusk, C. P.
10.1101/2021.02.22.432332 — cell biology — Posted on 2021-02-22
992 Resurrection of human endogenous retroviruses during aging reinforces senescence
Liu, X.; Liu, Z.; Sun, L.; Ren, J.; Wu, Z.; Jiang, X.; Ji, Q.; Wang, Q.; Fan, Y.; Cai, Y.; Wang, S.; Li, W.; Cao, G.; Song, M.; Lu, F.; Zhang, W.; Qu, J.; liu, g.
10.1101/2021.02.22.432260 — cell biology — Posted on 2021-02-22
993 Mitochondrial phenotypes in purified human immune cell subtypes and cell mixtures
Rausser, S.; Trumpff, C.; McGill, M. A.; Junker, A.; Wang, W.; Ho, S.-H.; Mitchell, A.; Karan, K. R.; Monk, C.; Segerstrom, S. C.; Reed, R. G.; Picard, M.
10.1101/2020.10.16.342923 — cell biology — Posted on 2021-02-22
994 Acquisition of the L452R mutation in the ACE2-binding interface of Spike protein triggers recent massive expansion of SARS-Cov-2 variants
Tchesnokova, V.; Kulakesara, H.; Larson, L.; Bowers, V.; Rechkina, E.; Kisiela, D.; Sledneva, Y.; Choudhury, D.; Maslova, I.; Deng, K.; Kutumbaka, K.; Geng, H.; Fowler, C.; Ralston, J. D.; Greene, D.; Samadpour, M.; Sokurenko, E. V.
10.1101/2021.02.22.432189 — microbiology — Posted on 2021-02-22
996 High-Throughput, Single-Copy Sequencing Reveals SARS-CoV-2 Spike Variants Coincident with Mounting Humoral Immunity during Acute COVID-19
Ko, S. H.; Bayat Mokhtari, E.; Mudvari, P.; Stein, S.; Stringham, C. D.; Wagner, D.; Ramelli, S.; Ramirez-Benitez, M. J.; Strich, J. R.; Davey, R. T.; Zhou, T.; Misasi, J.; Kwong, P. D.; Chertow, D. S.; Sullivan, N. J.; Boritz, E. A.
10.1101/2021.02.21.432184 — microbiology — Posted on 2021-02-22
997 Comparative analysis of host-associated variation in Phytophthora cactorum
Nellist, C. F.; Armitage, A. D.; Bates, H. J.; Sobczyk, M. K.; Luberti, M.; Lewis, L. A.; Harrison, R. J.
10.1101/2021.02.22.432166 — microbiology — Posted on 2021-02-22
998 The interspecific fungal hybrid Verticillium longisporum displays sub-genome-specific gene expression
Depotter, J.; van Beveren, F.; Rodriguez-Moreno, L.; Kramer, M.; Chavarro Carrero, E.; Lorencini Fiorin, G.; van den Berg, G.; Wood, T.; Thomma, B.; Seidl, M.
10.1101/341636 — microbiology — Posted on 2021-02-22
1002 Ribosomes in RNA granules are stalled on mRNA sequences that are consensus sites for FMRP association.
Anadolu, M. N.; Kailasam, s.; Simbriger, K.; Sun, J.; Markova, T.; Jafarnejad, S. M.; Lefebvre, F.; Ortega, J.; Gkogkas, C. G.; Sossin, W. S.
10.1101/2021.02.22.432349 — neuroscience — Posted on 2021-02-22
1003 Role of 5-HT2C receptors in zebrafish alarm reactions and post-exposure behavior
do Carmo Silva, R. X.; do Nascimento, B. G.; Gomes, G. C. V.; Holanda da Silva, N. A.; Pinheiro, J. S.; da Silva Chaves, S. N.; Pimentel, A. F. N.; Costa, B. P. D.; Herculano, A. M.; Lima-Maximino, M.; Maximino, C.
10.1101/2020.10.04.324202 — neuroscience — Posted on 2021-02-22
1004 Kynurenine pathway in post-mortem prefrontal cortex and cerebellum in schizophrenia: relationship with monoamines and symptomatology.
Afia, A. B.; Vila, E.; MacDowell, K. S.; Ormazabal, A.; Leza, J. C.; Haro, J.; Artuch, R.; Ramos, B.; Garcia-Bueno, B.
10.1101/2021.02.22.432214 — neuroscience — Posted on 2021-02-22
1005 Gradients of receptor expression in the macaque cortex
Froudist-Walsh, S.; Xu, T.; Niu, M.; Rapan, L.; Zilles, K.; Margulies, D. S.; Wang, X.-J.; Palomero-Gallagher, N.
10.1101/2021.02.22.432173 — neuroscience — Posted on 2021-02-22
1007 E. coli chemotaxis is information-limited
Mattingly, H. H.; Kamino, K.; Machta, B. B.; Emonet, T.
10.1101/2021.02.22.432091 — biophysics — Posted on 2021-02-22
1011 A spindle and thread-mechanism unblocks translation of N-terminally disordered proteins
Kaldmae, M.; Vosselman, T.; Zhong, X.; Lama, D.; Chen, G.; Saluri, M.; Kronqvist, N.; Siau, J. W.; Ng, A. S.; Ghadessy, F. J.; Sabatier, P.; Vojtesek, B.; Sarr, M.; Sahin, C.; Osterlund, N.; Ilag, L. I.; Vaananen, V. A.; Sedimbi, S.; Zubarev, R.; Nilsson, L.; Koeck, P. J.; Rising, A.; Fritz, N.; Johansson, J.; Lane, D. P.; Landreh, M.
10.1101/2021.02.22.432221 — biochemistry — Posted on 2021-02-22
1012 High Throughput Nanopore Sequencing of SARS-CoV-2 Viral Genomes from Patient Samples
Pater, A. A.; Bosmeny, M. S.; Parasrampuria, M.; Eddington, S. B.; Ovington, K. N.; White, A. A.; Barkau, C. L.; Metz, P. E.; Sylvain, R. J.; Chilamkurthy, R.; Yinusa, A. O.; Benzinger, S. W.; Hebert, M. M.; Gagnon, K. T.
10.1101/2021.02.09.430478 — genomics — Posted on 2021-02-22
1015 Engineering protease-resistant peptides to inhibit human parainfluenza viral respiratory infection
Outlaw, V. K.; Cheloha, R. W.; Jurgens, E.; Bovier, F. T.; Zhu, Y.; Kreitler, D. F.; Harder, O. K.; Niewiesk, S.; Porotto, M.; Gellman, S. H.; Moscona, A.
10.1101/2021.02.22.432312 — microbiology — Posted on 2021-02-22
1017 Physically interacting beta-delta pairs in the regenerating pancreas revealed by single cell sequencing
Yanowski, E.; Yacovzada, N. S.; David, E.; Giladi, A.; Jaitin, D.; Farack, L.; Egozi, A.; Ben-Zvi, D.; Itzkovitz, S.; Amit, I.; Hornstein, E.
10.1101/2021.02.22.432216 — cell biology — Posted on 2021-02-22
1018 GABARAP membrane conjugation sequesters the FLCN-FNIP tumor suppressor complex to activate TFEB and lysosomal biogenesis
Goodwin, J.; Walkup, W. G.; Hooper, K.; Li, T.; Kishi-Itakura, C.; Ng, A.; Lehmberg, T.; Jha, A.; Kommineni, S.; Fletcher, K.; Garcia-Fortanet, J.; Fan, Y.; Tang, Q.; Wei, M.; Agrawal, A.; Budhe, S. R.; Rouduri, S. R.; Baird, D.; Saunders, J.; Kiselar, J.; Chance, M. R.; Ballabio, A.; Appleton, B. A.; Brumell, J. H.; Florey, O.; Murphy, L. O.
10.1101/2021.02.22.432209 — cell biology — Posted on 2021-02-22
1019 Fundamental Role Of The H2A.Z C-Terminal Tail In The Formation Of Constitutive Heterochromatin
Imre, L.; Nanasi, P.; Bosire, R.; Csoti, A.; Enyedi, K. N.; Mezo, G.; Kusakabe, M.; Ausio, J.; Harata, M.; Szabo, G.
10.1101/2021.02.22.432230 — cell biology — Posted on 2021-02-22
1021 A novel glucocorticoid and androgen receptor modulator reduces viral entry and innate immune inflammatory responses in the Syrian Hamster model of SARS-CoV-2
Rocha, S. M.; Fagre, A. C.; Latham, A. S.; Popichak, K. A.; McDermott, C. P.; Dawson, C. C.; Lewis, J.; Reigan, P.; Aboellail, T. A.; Kading, R. C.; Schountz, T.; Theise, N. D.; Slayden, R. A.; Tjalkens, R. B.
10.1101/2021.02.20.432110 — immunology — Posted on 2021-02-22
1022 Reduced binding and neutralization of infection- and vaccine-induced antibodies to the B.1.351 (South African) SARS-CoV-2 variant
Edara, V. V.; Norwood, C.; Floyd, K.; Lai, L.; Davis-Gardner, M. E.; Hudson, W. H.; Mantus, G.; Nyhoff, L. E.; Adelman, M. W.; Fineman, R.; Patel, S.; Byram, R.; Gomes, D. N.; Michael, G.; Abdullahi, H.; Beydoun, N.; Panganiban, B.; McNair, N.; Hellmeister, K.; Pitts, J.; Winters, J.; Kleinhenz, J.; Usher, J.; O'Keefe, J. B.; Piantadosi, A.; Waggoner, J. J.; Babiker, A.; Stephens, D. S.; Anderson, E. J.; Edupuganti, S.; Rouphael, N.; Ahmed, R.; Wrammert, J.; Suthar, M. S.
10.1101/2021.02.20.432046 — immunology — Posted on 2021-02-22
1023 Structural Basis for Accommodation of Emerging B.1.351 and B.1.1.7 Variants by Two Potent SARS-CoV-2 Neutralizing Antibodies
Cerutti, G.; Rapp, M.; Guo, Y.; Bahna, F.; Bimela, J.; Reddem, E. R.; Yu, J.; Wang, P.; Liu, L.; Huang, Y.; Ho, D. D.; Kwong, P. D.; Sheng, Z.; Shapiro, L.
10.1101/2021.02.21.432168 — biochemistry — Posted on 2021-02-22
1025 Cardiac Atrial Compartmentalisation Proteomics: A Modified Density Gradient Method to Analyse Endo-lysosomal Proteins
Ayagama, T.; Bose, S. J.; Capel, R. A.; Priestman, D. A.; Berridge, G.; Fisher, R. J.; Galione, A.; Platt, F. M.; Kramer, H.; Burton, R. A. B.
10.1101/2021.02.22.432193 — molecular biology — Posted on 2021-02-22
1026 Statistical testing and annotation of gene transcriptomic-neuroimaging associations
Wei, Y.; de Lange, S. C.; Pijnenburg, R.; Scholtens, L. H.; Ardesch, D. J.; Watanabe, K.; Posthuma, D.; van den Heuvel, M. P.
10.1101/2021.02.22.432228 — neuroscience — Posted on 2021-02-22
1031 B/tMSI-CAST: a systematic approach for microsatellite instability detection in both tumor tissue and plasma specimens from next-generation sequencing data
Li, W.; Huang, F.; Huang, J.; YANG, J.; Zhang, H.; Zhao, L.; Xie, H.; Wang, X.; Hong, Y.; Shu, J.; Yu, J.; Li, Q.; Chen, W.; He, J.
10.1101/2021.02.22.432191 — bioinformatics — Posted on 2021-02-22
1033 Structure-function Specialisation of the Interfascicular Matrix in the Human Achilles Tendon
Patel, D.; Zamboulis, D. E.; Spiesz, E. M.; Simpson, D.; Birch, H. L.; Clegg, P. D.; Thorpe, C. T.; Screen, H. R. C.
10.1101/2021.02.22.432199 — bioengineering — Posted on 2021-02-22
1035 Chemical rescue of mutant proteins in living cells by naturally occurring small molecules
Hassell, D. S.; Steingesser, M. G.; Denney, A. S.; Johnson, C. R.; McMurray, M. A.
10.1101/2021.02.21.432174 — genetics — Posted on 2021-02-22
1040 Assembly of chromosome-scale and allele-aware autotetraploid genome of the Chinese alfalfa cultivar Zhongmu-4 and identification of SNP loci associated with 27 agronomic traits
Long, R.; Zhang, F.; Zhang, Z.; Li, M.; Chen, L.; Wang, X.; Liu, W.; Zhang, T.; Yu, L.-X.; He, F.; Jiang, X.; Yang, X.; Yang, C.; Wang, Z.; Kang, J.; Yang, Q.
10.1101/2021.02.21.428692 — plant biology — Posted on 2021-02-22
1041 IL-32 is a metabolic regulator promoting survival and proliferation of malignant plasma cells
Aass, K. R.; Mjelle, R.; Kastnes, M. H.; Tryggestad, S. S.; van den Brink, L. M.; Westhrin, M.; Zahoor, M.; Moen, S. H.; Buene, G.; Misund, K.; Sponaas, A.-M.; Ma, Q.; Sundan, A.; Groen, R. W.; Slordahl, T. S.; Waage, A.; Standal, T.
10.1101/2021.02.22.431638 — cancer biology — Posted on 2021-02-22
1043 A Framework for Evaluating Myocardial Stiffness Using 3D-Printed Hearts
Kolawole, F. O.; Peirlinck, M.; Cork, T. E.; Wang, V. Y.; Dual, S. S.; Levenston, M. O.; Kuhl, E.; Ennis, D. B.
10.1101/2021.02.21.432169 — bioengineering — Posted on 2021-02-22
1045 Rare genera differentiate urban green space soil bacterial communities in three cities across the world
Mills, J. G.; Selway, C. A.; Weyrich, L. S.; Skelly, C.; Weinstein, P.; Thomas, T.; Young, J. M.; Marczylo, E.; Yadav, S.; Yadav, V.; Lowe, A. J.; Breed, M. F.
10.1101/2021.02.21.432167 — ecology — Posted on 2021-02-22
1046 CCM2 deficient endothelial cells undergo a mechano-dependent reprogramming into senescence associated secretory phenotype used to recruit endothelial and immune cells.
Vannier, D. R.; Shapeti, A.; Chuffart, F.; Planus, E.; Manet, S.; Rivier, P.; destaing, o.; Albiges-Rizo, C.; Van Oosterwyck, H.; Faurobert, E.
10.1101/2021.02.22.432204 — cell biology — Posted on 2021-02-22
1047 Nanoscale dynamics of cellulase TrCel7A digesting cellulose
Haviland, Z. K.; Nong, D.; Vasquez Kuntz, K.; Starr, T. J.; Ma, D.; Tien, M.; Anderson, C. T.; Hancock, W. O.
10.1101/2021.02.18.431891 — plant biology — Posted on 2021-02-22
1049 NAMPT-derived NAD+ fuels PARP1 to promote skin inflammation through parthanatos
Martinez-Morcillo, F. J.; Canton-Sandoval, J.; Martinez-Navarro, F. J.; cabas, I.; Martinez-Vicente, I.; Armistead, J.; Hatzold, J.; Lopez-Munoz, A.; Martinez-Menchon, T.; Corbalan-Velez, R.; Lacal, J.; Hammerschmidt, M.; Garcia-Borron, J. C.; Garcia-Ayala, A.; Cayuela, M. L.; Perez-Oliva, A. B.; Garcia-Moreno, D.; Mulero, V.
10.1101/2021.02.19.431942 — immunology — Posted on 2021-02-22
1051 BTBD9 is a novel component of IGF signaling and regulates manganese-induced dopaminergic dysfunction
Chen, P.; Zheng, F.; Li, S.; Cheng, H.; Bornhorst, J.; Li, Y.; Yang, B.; Lee, K. H.; Ke, T.; Schwerdtle, T.; Yang, X.; Bowman, A. B.; Aschner, M.
10.1101/2021.02.18.431924 — neuroscience — Posted on 2021-02-22
1052 Time-restricted feeding near dawn entrains long-term behavioral changes through the suprachiasmatic nucleus
Zhai, Q.; Zheng, Y.; Gu, Y.; Zhang, T.; Yuan, B.; Wang, T.; Yan, J.; Qin, H.; Yang, L.; Chen, X.; Vidal-Puig, A.; Xu, Y.
10.1101/2021.02.18.431900 — physiology — Posted on 2021-02-22
1053 Comprehensive Assessment of Somatic Copy Number Variation Calling Using Next-Generation Sequencing Data
Chen, Y.-C.; Seifuddin, F.; Nguyen, C.; Yang, Z.; Chen, W.; Yan, C.; Chen, Q.; Wang, C.; Xiao, W.; Pirooznia, M.; Meerzaman, D.; The Somatic Mutation Working Group of the SEQC-II Consortium,
10.1101/2021.02.18.431906 — bioinformatics — Posted on 2021-02-22
1056 Multi-omics reveal intricate network of mitochondrial adaptations to training in human skeletal muscle
Granata, C.; Caruana, N. J.; Botella, J.; Jamnick, N. A.; Huynh, K.; Kuang, J.; Janssen, H. A.; Reljic, B.; Mellett, N. A.; Laskowski, A.; Stait, T. L.; Frazier, A. E.; Coughlan, M. T.; Meikle, P. J.; Thorburn, D. R.; Stroud, D. A.; Bishop, D. J.
10.1101/2021.02.19.431993 — cell biology — Posted on 2021-02-22
1057 Investigating the chemolithoautotrophic and formate metabolism of Nitrospira moscoviensis by constraint-based metabolic modeling and 13C-tracer analysis
Lawson, C. E.; Mundinger, A. B.; Koch, H.; Jacobson, T. B.; Weathersby, C. A.; Jetten, M. S.; Pabst, M.; Amador-Noguez, D.; Noguera, D. R.; McMahon, K.; Lücker, S.
10.1101/2021.02.18.431926 — microbiology — Posted on 2021-02-22
1058 Restoration of BDNF-TrkB signaling rescues deficits in a mouse model of SCA6
Cook, A. A.; Jayabal, S.; Sheng, J.; Fields, E.; Leung, T. C. S.; Quilez, S.; McNicholas, E.; Lau, L.; Watt, A. J.
10.1101/2021.02.21.432180 — neuroscience — Posted on 2021-02-22
1059 Quantitative profiling of axonal guidance proteins during the differentiation of human neurospheres
Goto-Silva, L.; Martins, M.; Murillo, J. R.; Rocha, L.; Vitoria, G.; Oliveira, J. T.; Nascimento, J. M.; Loiola, E. C.; Nogueira, F. C. S.; Domont, G. B.; Guimaraes, M. Z. P.; Tovar-Moll, F.; Rehen, S. K.; Junqueira, M.
10.1101/2021.02.21.432144 — neuroscience — Posted on 2021-02-22
1063 Sterile Inflammation Alters Neutrophil Kinetics in Mice
Singh, A.; Jothiprakasam, T.; Raghavan, J. V.; Jhunjhunwala, S.
10.1101/2021.02.12.430891 — immunology — Posted on 2021-02-22
1065 Discovering footprints of evolutionary chromatin response to transposons activity: merging biophysics with bioinformatics
Vitali, S.; Giampieri, E.; Sala, C.; Do Valle, I.; Criscione, S.; Neretti, N.; Castellani, G.
10.1101/513572 — biophysics — Posted on 2021-02-22
1067 Hippocampal sharp wave-ripples and the associated sequence replay emerge from structured synaptic interactions in a network model of area CA3
Ecker, A.; Bagi, B.; Vertes, E.; Steinbach-Nemeth, O.; Karlocai, M. R.; Papp, O. I.; Miklos, I.; Hajos, N.; Freund, T. F.; Gulyas, A. I.; Kali, S.
10.1101/2021.02.18.431868 — neuroscience — Posted on 2021-02-22
1068 Quantifying Viscous Damping and Stiffness in Parkinsonism Using Data-Driven Model Estimation
Werning, A.; Umbarila, D.; Fite, M.; Fergus, S.; Zhang, J.; Molnar, G. F.; Johnson, L. A.; Wang, J.; Vitek, J. L.; Escobar Sanabria, D.
10.1101/2021.02.17.431730 — bioengineering — Posted on 2021-02-22
1070 Simultaneously monitoring aquatic and riparian biodiversity using riverine water eDNA
YANG, H.; DU, H.; QI, H.; YU, L.; HOU, X.; ZHANG, H.; LI, J.; WU, J.; WANG, C.; ZHOU, Q.; WEI, Q.
10.1101/2020.06.20.162388 — ecology — Posted on 2021-02-22
1072 TemplateFlow: a community archive of imaging templates and atlases for improved consistency in neuroimaging
Ciric, R.; Lorenz, R.; Thompson, W. H.; Goncalves, M.; MacNicol, E.; Markiewicz, C.; Halchenko, Y.; Ghosh, S. S.; Gorgolewski, K. J.; Poldrack, R.; Esteban, O.
10.1101/2021.02.10.430678 — neuroscience — Posted on 2021-02-22
1073 Motor and Sensory Cortical Processing of Neural Oscillatory Activities revealed by Human Swallowing using Intracranial Electrodes
Hashimoto, H.; Takahashi, K.; Kameda, S.; Yoshida, F.; Maezawa, H.; Oshino, S.; Tani, N.; Khoo, H. M.; Yanagisawa, T.; Yoshimine, T.; Kishima, H.; Hirata, M.
10.1101/2020.07.21.213868 — neuroscience — Posted on 2021-02-22
1075 Paths to Oblivion: Common Neural Mechanisms of Anaesthesia and Disorders of Consciousness
Luppi, A. I.; Mediano, P. A. M.; Rosas, F. E.; Allanson, J.; Pickard, J. D.; Williams, G. B.; Craig, M. M.; Finoia, P.; Peattie, A. R. D.; Coppola, P.; Owen, A. M.; Naci, L.; Menon, D. K.; Bor, D.; Stamatakis, E. A.
10.1101/2021.02.14.431140 — neuroscience — Posted on 2021-02-22
1078 Plant trait heterosis is quantitatively associated with expression heterosis of plastid ribosomal proteins
Birdseye, D.; De Boer, L.; Shen, Z.; Bai, H.; Zhou, P.; Schmelz, E. A.; Springer, N. M.; Briggs, S.
10.1101/2021.02.16.431485 — plant biology — Posted on 2021-02-22
1080 Single cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree
Hendley, A. M.; Rao, A. A.; Leonhardt, L.; Ashe, S.; Smith, J. A.; Giacometti, S.; Peng, X. L.; Jiang, H.; Berrios, D.; Pawlak, M.; Li, L. Y.; Lee, J.; Collisson, E. A.; Anderson, M.; Fragiadakis, G. K.; Yeh, J. J.; Chun, J. Y.; Kim, G. E.; Weaver, V. M.; Hebrok, M.
10.1101/2020.10.12.336784 — bioinformatics — Posted on 2021-02-22
1081 Secondary Structure Motifs Made Searchable to Facilitate the Functional Peptide Design
Tsai, C.-Y.; Salawu, E. O.; Li, H.; Lin, G.-Y.; Kuo, T.-Y.; Voon, L.; Sharma, A.; Hu, K.-D.; Cheng, Y.-Y.; Sahoo, S.; Stuart, L.; Chen, C.-W.; Chang, Y.-Y.; Lu, Y.-L.; Ke, X.; Lan, C.-Y.; Fu, H.-W.; Yang, L.-W.
10.1101/651315 — bioinformatics — Posted on 2021-02-22
1083 Flexible multivariate linear mixed models for structured multiple traits
Kim, H.; Farage, G.; Lovell, J. T.; Mckay, J. K.; Juenger, T. E.; Sen, S.
10.1101/2020.03.27.012690 — genetics — Posted on 2021-02-22
1085 Insulin-dependent maturation of newly generated olfactory sensory neurons after injury
Kuboki, A.; Kikuta, S.; Otori, N.; Kojima, H.; Matsumoto, I.; Reisert, J.; Yamasoba, T.
10.1101/2021.02.21.432129 — neuroscience — Posted on 2021-02-21
1088 Inhibition of SARS-CoV-2 infection in human cardiomyocytes by targeting the Sigma-1 receptor disrupts cytoskeleton architecture and contractility
Salerno, J. A.; Torquato, T.; Temerozo, J. R.; Goto-Silva, L.; Mendes, M. A.; Sacramento, C. Q.; Fintelman-Rodrigues, N.; Vitoria, G.; Souza, L. R. Q.; Ornelas, I. M.; Verissimo, C.; Karmirian, K.; Pedrosa, C. d. S. G.; Dias, S. d. S. G.; Soares, V. C.; Aragao, L. G. H. S.; Puig-Pijuan, T.; Salazar, V. W.; Dariolli, R.; Biagi, D.; Furtado, D. R.; Borges, H. L.; Bozza, P. T.; Guimaraes, M. Z. P.; Souza, T. M. L.; Rehen, S.
10.1101/2021.02.20.432092 — cell biology — Posted on 2021-02-21
1090 DpaA detaches Braun's lipoprotein from peptidoglycan
Winkle, M.; Hernandez-Rocamora, V. M.; Pullela, K.; Goodall, E. C. A.; Martorana, A. M.; Gray, J.; Henderson, I. R.; Polissi, A.; Vollmer, W.
10.1101/2021.02.21.432140 — microbiology — Posted on 2021-02-21
1092 Structural insight into host plasma membrane association and assembly of HIV-1 Matrix protein
Ciftci, H.; Tateishi, H.; Koiwai, K.; Koga, R.; Anraku, K.; Monde, K.; Dag, C.; Destan, E.; Yuksel, B.; Ayan, E.; Yildirim, G.; Yigin, M.; Ertem, F. B.; Shafiei, A.; Guven, O.; Besler, S. O.; Sierra, R. G.; Yoon, C. H.; Su, Z.; Liang, M.; Acar, B.; Haliloglu, T.; Otsuka, M.; Yumoto, F.; Fujita, M.; Senda, T.; DeMirci, H.
10.1101/2021.02.21.432153 — microbiology — Posted on 2021-02-21
1093 Extracellular Delivery of Functional Mitochondria Reverses the Dysfunction of CD4+ T Cells in Aging
Headley, C. A.; Gautam, S.; Akhter, A.; Dwivedi, V.; Ault, R.; Torrelles, J. B.; Gelfond, J. A. L.; Turner, J.
10.1101/2021.02.21.432151 — immunology — Posted on 2021-02-21
1094 Synchrony of mind and body are distinct in mother-child dyads
Reindl, V.; Wass, S.; Leong, V.; Scharke, W.; Wistuba, S.; Wirth, C. L.; Konrad, K.; Gerloff, C.
10.1101/2021.02.21.432077 — neuroscience — Posted on 2021-02-21
1095 Analysis Of Molecular Networks In The Cerebellum In Chronic Schizophrenia: Modulation By Early Postnatal Life Stressors In Murine Models
Vera-Montecinos, A.; Rodriguez-Mias, R.; MacDowell, K. S.; Garcia-Bueno, B.; Leza, J. C.; Villen, J.; Ramos, B.
10.1101/2021.02.21.432145 — neuroscience — Posted on 2021-02-21
1098 A cannabinoid receptor agonist shows anti-inflammatory and survival properties in human SARS-CoV-2-infected iPSC-derived cardiomyocytes
Aragao, L. G. H. S.; Oliveira, J. T.; Temerozo, J. R.; Mendes, M. A.; Salerno, J. A.; Pedrosa, C. d. S. G.; Puig-Pijuan, T.; Verissimo, C.; Ornelas, I. M.; Torquato, T.; Vitoria, G.; Sacramento, C. Q.; Fintelman-Rodrigues, N.; Dias, S. d. S. G.; Cardoso Soares, V.; Souza, L. R. Q.; Karmirian, K.; Goto-Silva, L.; Biagi, D.; Cruvinel, E. M.; Dariolli, R.; Furtado, D. R.; Bozza, P. T.; Borges, H. L.; Souza, T. M. L.; Guimaraes, M. Z. P.; Rehen, S.
10.1101/2021.02.20.431855 — cell biology — Posted on 2021-02-21
1101 Unraveling the role of MADS transcription factor complexes in apple tree dormancy using sequential DAP-seq
Falavigna, V. d. S.; Severing, E.; Lai, X.; Estevan, J.; Farrera, I.; Hugouvieux, V.; Zubieta, C.; Coupland, G.; Costes, E.; Andres, F.
10.1101/2021.02.21.431301 — plant biology — Posted on 2021-02-21
1102 Finding Druggable Sites in Proteins using TACTICS
Evans, D. J.; Yovanno, R. A.; Rahman, S.; Cao, D. W.; Beckett, M. Q.; Patel, M. H.; Bandak, A. F.; Lau, A. Y.
10.1101/2021.02.21.432120 — biophysics — Posted on 2021-02-21
1103 GAMIBHEAR: whole-genome haplotype reconstruction from Genome Architecture Mapping data
Markowski, J.; Kempfer, R.; Kukalev, A.; Irastorza-Azcarate, I.; Loof, G.; Kehr, B.; Pombo, A.; Rahmann, S.; Schwarz, R. F.
10.1101/2020.01.30.927061 — bioinformatics — Posted on 2021-02-21
1105 Causal approach to environmental risks of seabed mining
Kaikkonen, L.; Helle, I.; Kostamo, K.; Kuikka, S.; Nygard, H.; Törnroos, A.; Venesjärvi, R.; Uusitalo, L.
10.1101/2021.02.21.432138 — ecology — Posted on 2021-02-21
1109 Non-canonical role of Hippo tumor suppressor serine/threonine kinase 3 STK3 in prostate cancer
Schirmer, A. U.; Driver, L. M.; Zhao, M. T.; Wells, C. I.; Pickett, J. E.; O'Bryne, S. N.; Eduful, B. J.; Yang, X.; Howard, L.; You, S.; Devi, G. R.; Digiovanni, J.; Freedland, S. F.; Chi, J.-T. A.; Drewry, D.; Macias, E.
10.1101/2021.02.21.432137 — cancer biology — Posted on 2021-02-21
1112 Young and Undamaged rMSA Improves the Longevity of Mice
Tang, J.; Ju, A.; Li, B.; Zhang, S.; Gong, Y.; Ma, B.; Jiang, Y.; Liu, H.; Fu, Y.; Luo, Y.
10.1101/2021.02.21.432135 — biochemistry — Posted on 2021-02-21
1115 Modulating the properties of DNA-SWCNT sensors using chemically modified DNA
Gillen, A. J.; Lambert, B. P.; Antonucci, A.; Molina-Romero, D.; Boghossian, A. A.
10.1101/2021.02.20.432105 — bioengineering — Posted on 2021-02-21
1116 Ku70 suppresses alternative end-joining in G1-arrested progenitor B cells
Liang, Z.; Kumar, V.; Le Bouteiller, M.; Zurita, J.; Kenrick, J.; Lin, S. G.; Lou, J.; Hu, J.; Ye, A. Y.; Boboila, C.; Alt, F. W.; Frock, R. L.
10.1101/2021.02.20.432121 — genetics — Posted on 2021-02-21
1120 Comparative analysis of 16S rRNA gene and metagenome sequencing in pediatric gut microbiomes
Peterson, D.; Bonham, K. S.; Rowland, S.; Pattanayak, C. W.; RESONANCE Consortium, ; Klepac-Ceraj, V.
10.1101/2021.02.20.432118 — microbiology — Posted on 2021-02-21
1121 Microstates and power envelope hidden Markov modeling probe bursting brain activity at different timescales
Coquelet, N.; De Tiege, X.; Roshchupkina, L.; Peigneux, P.; Goldman, S.; Woolrich, M. W.; Wens, V.
10.1101/2021.02.20.432128 — neuroscience — Posted on 2021-02-21
1123 Pathogen community composition and co-infection patterns in a wild community of rodents
Abbate, J. L.; Galan, M.; Razzauti, M.; Sironen, T.; Voutilainen, L.; Henttonen, H.; Gasqui, P.; Cosson, J.-F.; Charbonnel, N.
10.1101/2020.02.09.940494 — ecology — Posted on 2021-02-21
1124 STAG proteins promote cohesin ring loading at R-loops.
Porter, H.; Li, Y.; Varsally, W.; Neguembor, M. V.; Beltran, M.; Pezic, D.; Martin, L.; Tavares Cornejo, M.; Bhamra, A.; Surinova, S.; Jenner, R. G.; Cosma, M. P.; HADJUR, S.
10.1101/2021.02.20.432055 — cell biology — Posted on 2021-02-21
1125 Architecture and assembly dynamics of the essential mitochondrial TIM chaperone systems
Weinhäupl, K.; Wang, Y.; Hessel, A.; Brennich, M.; Lindorff-Larsen, K.; Schanda, P.
10.1101/2020.03.13.990150 — biophysics — Posted on 2021-02-21
1127 Notch-Jagged signaling complex defined by an interaction mosaic
Zeronian, M. R.; Klykov, O.; Portell i de Montserrat, J.; Konijnenberg, M. J.; Gaur, A.; Scheltema, R. A.; Janssen, B. J. C.
10.1101/2021.02.19.432005 — molecular biology — Posted on 2021-02-21
1128 Dorsal raphe nucleus to anterior cingulate cortex 5-HTergic neural circuit modulates consolation and sociability
Li, L.-F.; Zhang, L.-Z.; He, Z.-X.; Zhang, Y.-T.; Yuan, W.; Ma, H.; Xun, Y.-F.; Hou, W.-J.; Li, Y.-T.; Lv, Z.-J.; Jia, R.; Tai, F.
10.1101/2020.09.21.307280 — neuroscience — Posted on 2021-02-20
1131 Screening by deep sequencing reveals mediators of miRNA tailing in C. elegans
Prothro, K. P.; Vieux, K.-F.; Palmer, C.; Veksler-Lublinsky, I. I.; McJunkin, K.
10.1101/2021.01.11.426275 — molecular biology — Posted on 2021-02-20
1132 DNA-Encoded Multivalent Display of Protein Tetramers on Phage: Synthesis and In Vivo Aplications
Lima, G. M.; Atrazhev, A.; Sarkar, S.; Sojitra, M.; Reddy, R.; Macauley, M. S.; Monteiro, G.; Derda, R.
10.1101/2021.02.20.432100 — molecular biology — Posted on 2021-02-20
1133 LayNii: A software suite for layer-fMRI.
Huber, L.; Poser, B. A.; Bandettini, P. A.; Arora, K.; Wagstyl, K.; Cho, S.; Goense, J.; Nothnagel, N.; Morgan, A. T.; Mueller, A. K.; van den Hurk, J.; Reynolds, R. C.; Glen, D. R.; Goebel, R. W.; Gulban, O. F.
10.1101/2020.06.12.148080 — neuroscience — Posted on 2021-02-20
1134 Predictive Coding Models for Pain Perception
Song, Y.; Yao, M.; Kemprecos, H.; byrne, a.; Xiao, Z.; Zhang, Q.; Singh, A.; Wang, J.; Chen, Z. S.
10.1101/843284 — neuroscience — Posted on 2021-02-20
1135 Reversible fronto-occipitotemporal signaling complements task encoding and switching under ambiguous cues
Tsumura, K.; Kosugi, K.; Hattori, Y.; Aoki, R.; Takeda, M.; Chikazoe, J.; Nakahara, K.; Jimura, K.
10.1101/2020.07.29.227736 — neuroscience — Posted on 2021-02-20
1140 Genetic Association Study of Childhood Aggression across raters, instruments and age
Ip, H. F.; van der Laan, C. M.; Krapohl, E. M. L.; Brikell, I.; Sanchez-Mora, C.; Nolte, I. M.; St Pourcain, B.; Bolhuis, K.; Palviainen, T.; Zafarmand, H.; Colodro-Conde, L.; Gordon, S.; Zayats, T.; Aliev, F.; Jiang, C.; Wang, C. A.; Saunders, G.; Karhunen, V.; Hammerschlag, A. R.; Adkins, D. E.; Border, R.; Peterson, R. E.; Prinz, J. A.; Thiering, E.; Seppälä, I.; Vilor-Tejedor, N.; Ahluwalia, T. S.; Day, F. R.; Hottenga, J.-J.; Allegrini, A. G.; Rimfeld, K.; Chen, Q.; Lu, Y.; Martin, J.; Soler Artigas, M.; Rovira, P.; Bosch, R.; Espanol, G.; Ramos Quiroga, J. A.; Neumann, A.; Ensink, J.;
10.1101/854927 — genomics — Posted on 2021-02-20
1141 Target enrichment and extensive population sampling help untangle the recent, rapid radiation of Oenothera sect. Calylophus
Cooper, B. J.; Moore, M. J.; Douglas, N. A.; Wagner, W. L.; Johnson, M. G.; Overson, R. P.; McDonnell, A. J.; Fant, J. B.; Skogen, K. A.; Wickett, N. J.
10.1101/2021.02.20.432097 — evolutionary biology — Posted on 2021-02-20
1143 Deep ancestral introgression shapes evolutionary history of dragonflies and damselflies
Suvorov, A.; Scornavacca, C.; Fujimoto, M. S.; Bodily, P.; Clement, M.; Crandall, K. A.; Whiting, M. F.; Schrider, D. R.; Bybee, S. M.
10.1101/2020.06.25.172619 — evolutionary biology — Posted on 2021-02-20
1148 Improving stroke detection via Correlation Tensor MRI
Alves, R.; Henriques, R. N.; Kerkela, L.; Chavarrias, C.; Jespersen, S.; Shemesh, N.
10.1101/2021.02.20.432088 — neuroscience — Posted on 2021-02-20
1149 The structural connectome constrains fast brain dynamics
Sorrentino, P.; Seguin, C.; Rucco, R.; Liparoti, M.; Troisi Lopez, E.; Bonavita, S.; Quarantelli, M.; Sorrentino, G.; Jirsa, V.; Zalesky, A.
10.1101/2020.11.25.393017 — neuroscience — Posted on 2021-02-20
1151 High Light and High Temperature Reduce Photosynthesis via Different Mechanisms in the C4 Model Setaria viridis
Anderson, C. M.; Mattoon, E. M.; Zhang, N.; Becker, E.; McHargue, W.; Yang, J.; Patel, D.; Dautermann, O.; McAdam, S. A. M.; Tarin, T.; Pathak, S.; Avenson, T. J.; Berry, J.; Braud, M.; Niyogi, K. K.; Wilson, M.; Nusinow, D. A.; Vargas, R.; Czymmek, K. J.; Eveland, A. L.; Zhang, R.
10.1101/2021.02.20.431694 — plant biology — Posted on 2021-02-20
1154 Waves of sumoylation support transcription dynamics during adipocyte differentiation
Zhao, X.; Hendriks, I. A.; Le Gras, s.; Ye, T.; Nguea P, A.; Flor Lien, G.; Ramos-Alonso, L.; Klungland, A.; Jost, B.; Enserink, J. M.; Nielsen, M. L.; Chymkowitch, P.
10.1101/2021.02.20.432084 — genomics — Posted on 2021-02-20
1155 RNA-binding proteins regulate aldosterone homeostasis in human steroidogenic cells
Fu, R.; Wellman, K.; Baldwin, A.; Rege, J.; Walters, K.; Hirsekorn, A.; Riemondy, K.; Rainey, W. E.; Mukherjee, N.
10.1101/2021.02.19.431050 — genomics — Posted on 2021-02-20
1158 A conserved paint box underlies color pattern diversity in Estrildid finches
Hidalgo, M.; Curantz, C.; Quenech'Du, N.; Gluckman, T.-L.; Neguer, J.; Beck, S.; Mohammad, A.; Manceau, M.
10.1101/2021.02.19.431992 — developmental biology — Posted on 2021-02-20
1159 Unique functions for Notch4 in murine embryonic lymphangiogenesis
Muley, A.; Kim Uh, M.; James, J. M.; Murtomaki, A.; McCarron, J. D.; Kitajewski, C.; Gnarra, M.; Riitano, G.; Mukouyama, Y.-s.; Kitajewski, J.; Shawber, C. J.
10.1101/2021.02.19.431982 — developmental biology — Posted on 2021-02-20
1162 STAG proteins promote cohesin ring loading at R-loops.
HADJUR, S.; Porter, H.; Li, Y.; Varsally, W.; Neguembor, M. V.; Beltran, M.; Pezic, D.; Martin, L.; Tavares Cornejo, M.; Bhamra, A.; Surinova, S.; Jenner, R. G.; Cosma, M.
10.1101/2021.02.20.432055 — cell biology — Posted on 2021-02-20
1164 Daily orexinergic modulation of the rat superficial layers of the superior colliculus - implications for intrinsic clock activities in the visual system
Chrobok, L.; Jeczmien-Lazur, J. S.; Bubka, M.; Pradel, K.; Klekocinska, A.; Klich, J. D.; Ridla Rahim, A.; Myung, J.; Kepczynski, M.; Lewandowski, M. H.
10.1101/2021.02.20.432093 — neuroscience — Posted on 2021-02-20
1165 Behavioral deficits, learning impairment, and enhanced hippocampal excitability in co-isogenic PrnpZH3/ZH3 mice
Matamoros-Angles, A.; Hervera, A.; Soriano, J.; Marti, E.; Carulla, P.; LLorens, F.; Nuvolone, M.; Aguzzi, A.; Ferrer, I.; Gruart, A.; Delgado-Garcia, J. M.; del Rio, J. A.
10.1101/2021.02.20.432083 — neuroscience — Posted on 2021-02-20
1166 A neural circuit basis for bilateral olfactory input-enhanced chemosensory avoidance navigation
Sy, S. K. H.; Chan, D. C. W.; Lai, H.-M.; Li, Z.; Wong, K. K. Y.; Choi, C. H. J.; Mok, V. C. T.; Hu, Y.; Ko, H.
10.1101/2021.02.20.431946 — neuroscience — Posted on 2021-02-20
1172 Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19
Ziegler, C. G. K.; Miao, V. N.; Owings, A. H.; Navia, A. W.; Tang, Y.; Bromley, J. D.; Lotfy, P.; Sloan, M.; Laird, H.; Williams, H. B.; George, M.; Drake, R. S.; Christian, T.; Parker, A.; Sindel, C. B.; Burger, M. W.; Pride, Y.; Hasan, M.; Abraham, G. E.; Senitko, M.; Robinson, T. O.; Shalek, A. K.; Glover, S. C.; Horwitz, B. H.; Ordovas-Montanes, J.
10.1101/2021.02.20.431155 — immunology — Posted on 2021-02-20
1175 Biochemical Methane Potential (BMP) from sugarcane biorefinery residues: maximizing their use by co-digestion
Volpi, M. P. C.; de Paiva, L. B. B.; Mockaitis, G.; Rabelo, S. C.; Franco, T. T.; Moraes, B. d. S.
10.1101/2021.02.19.432018 — bioengineering — Posted on 2021-02-20
1177 Harnessing the Power of Antibodies to Fight Bone Metastasis
Tian, Z.; Wu, L.; Yu, C.; Chen, Y.; Xu, Z.; Bado, I.; Loredo, A.; Wang, L.; Wang, H.; Wu, K.-l.; Zhang, W.; Zhang, X.; Xiao, H.
10.1101/2021.02.19.432037 — cancer biology — Posted on 2021-02-20
1178 Selective stimulation of the ferret abdominal vagus nerve with multi-contact nerve cuff electrodes
Shulgach, J. A.; Beam, D. W.; Nanivadekar, A. C.; Miller, D. M.; Fulton, S.; Sciullo, M.; Ogren, J.; Wong, L.; McLaughlin, B.; Yates, B. J.; Horn, C.; Fisher, L.
10.1101/2021.02.19.431879 — bioengineering — Posted on 2021-02-20
1180 Genome-wide association study reveals an independent genetic basis of zinc and cadmium concentrations in fresh sweet corn kernels
Baseggio, M.; Murray, M.; Wu, D.; Ziegler, G.; Kaczmar, N.; Chamness, J.; Hamilton, J. P.; Buell, C. R.; Vatamaniuk, O. K.; Buckler, E. S.; Smith, M. E.; Baxter, I.; Tracy, W. F.; Gore, M. A.
10.1101/2021.02.19.432009 — genetics — Posted on 2021-02-20
1184 Direct tissue sensing reprograms TLR4+ Tfh-like cells inflammatory profile in the joints of rheumatoid arthritis patients
Amaral-Silva, D.; Torrao, R. C.; Torres, R.; Falcao, S.; Goncalves, M. J.; Araujo, M. P.; Martins, M. J.; Lopes, C.; Neto, A.; Marona, J.; Costa, T.; Castelao, W.; Silva, A. B.; Silva, I.; Lourenco, M. H.; Mateus, M.; Pina Goncalves, N.; Manica, S.; Costa, M.; Pimentel-Santos, F.; Mourao, A. F.; Branco, J. C.; Soares, H.
10.1101/2021.02.19.431679 — immunology — Posted on 2021-02-20
1185 Precision Diffusion Imaging
Seider, N. A.; Adeyemo, B.; Miller, R.; Newbold, D. J.; Hampton, J. M.; Scheidter, K. M.; Rutlin, J.; Laumann, T. O.; Roland, J. L.; Montez, D. F.; Van, A. N.; Zheng, A.; Marek, S.; Kay, B. P.; Bretthorst, G. L.; Schlaggar, B. L.; Greene, D. J.; Wang, Y.; Petersen, S. E.; Gordon, E. M.; Snyder, A. Z.; Shimony, J. S.; Dosenbach, N. U.
10.1101/2021.02.19.432023 — neuroscience — Posted on 2021-02-20
1186 Long-term association of pregnancy and maternal brain structure: the Rotterdam Study
Aleknaviciute, J.; Evans, T.; Aribas, E.; de Vries, M. W.; Steegers, E. A. P.; Ikram, M. A.; Tiemeier, H.; Kavousi, M.; Vernooij, M. W.; Kushner, S. A.
10.1101/2021.02.19.432038 — neuroscience — Posted on 2021-02-20
1189 Actinidia seed-born latent virus is transmitted paternally and maternally at high rates
Amponsah, N. T.; van den Brink, R.; Datson, P. M.; Austin, P. T.; Horner, M.; MacDiarmid, R. M.
10.1101/2021.02.19.432071 — pathology — Posted on 2021-02-20
1190 High levels of truncated RHAMM cooperate with dysfunctional p53 to accelerate theprogression of pancreatic cancer
Feng, J.; Lin, A.; Chen, X.; Wang, D.; Wong, M.; Zhang, G.; Na, J.; Zhang, T.; Chen, Z.; Chen, Y.-T.; Du, Y.-C. N.
10.1101/2021.02.19.432042 — cancer biology — Posted on 2021-02-20
1192 Squidpy: a scalable framework for spatial single cell analysis
Palla, G.; Spitzer, H.; Klein, M.; Fischer, D. S.; Schaar, A. C.; Kuemmerle, L. B.; Rybakov, S.; Ibarra, I. L.; Holmberg, O.; Virshup, I.; Lotfollahi, M.; Richter, S.; Theis, F. J.
10.1101/2021.02.19.431994 — bioinformatics — Posted on 2021-02-20
1193 Competitive coordination of the dual roles of the Hedgehog co-receptor in homophilic adhesion and signal reception
Yang, S.; Zhang, Y.; Yang, C.; Wu, X.; El Oud, S. M.; Chen, R.; Cai, X.; Wu, X.; Lan, G.; Zheng, X.
10.1101/2021.02.19.432013 — bioinformatics — Posted on 2021-02-20
1196 No evidence for short-term evolutionary response to a warming environment in Drosophila
Santos, M. A.; Carromeu-Santos, A.; Quina, A. S.; Santos, M.; Matos, M.; Simoes, P.
10.1101/2021.02.19.432014 — evolutionary biology — Posted on 2021-02-20
1197 Evaluating how lethal management affects poaching of Mexican wolves
Louchouarn, N. X.; Santiago-Avila, F. J.; Parsons, D. R.; Treves, A.
10.1101/2021.02.19.432027 — ecology — Posted on 2021-02-20
1199 Optimizing EEG source reconstruction with concurrent fMRI-derived spatial priors
Abreu, R.; Soares, J. F.; Batista, S.; Lima, A. C.; Sousa, L.; Castelo-Branco, M.; Duarte, J. V.
10.1101/2021.02.19.431976 — neuroscience — Posted on 2021-02-20
1203 Individual variation in brain microstructural-cognition relationships in aging
Patel, R.; Mackay, C. E.; Jansen, M. G.; Devenyi, G.; O'Donoghue, M. C.; Kivimäki, M.; Singh-Manoux, A.; Zsoldos, E.; Ebmeier, K. P.; Chakravarty, M.; Suri, S.
10.1101/2021.02.19.431732 — neuroscience — Posted on 2021-02-20
1204 A photoswitchable GPCR-based opsin for presynaptic silencing
Copits, B. A.; O'Neill, P. R.; Gowrishankar, R.; Yoo, J. J.; Meshik, X.; Parker, K. E.; Spangler, S. M.; Vasquez, A. M.; Elerding, A. J.; Stander, M. C.; Kalyanaraman, V.; Vogt, S. K.; Samineni, V. K.; Gautam, N.; Sunahara, R. K.; Gereau, R. W.; Bruchas, M. R.
10.1101/2021.02.19.432008 — neuroscience — Posted on 2021-02-20
1205 Rice NIN-LIKE PROTEIN 3 plays a significant role in nitrogen use efficiency and grain yield under nitrate-sufficient conditions
Xiang, C.; Zhang, Z.-S.; Xia, J.-Q.; Alfatih, A.; Song, Y.; Huang, Y.-J.; Sun, L.-Q.; Wan, G.-Y.; Wang, S.; Wang, Y.; Hu, B.-H.; Zhang, G.; Peng, Q.; Li, S.; Yu, L.; Wu, J.
10.1101/2021.02.19.432039 — plant biology — Posted on 2021-02-20
1206 Divergence in a stress-associated gene regulatory network underlies differential growth control in the Brassicaceae family
Sun, Y.; Oh, D.-H.; Duan, L.; Ramachandran, P.; Ramirez, A.; Bartlett, A.; Dassanayake, M.; Dinneny, J. R.
10.1101/2020.11.18.349449 — plant biology — Posted on 2021-02-20
1207 Defining the transcriptional signature of esophageal-to-skin lineage conversion
Bejar, M. T.; Jimenez-Gomez, P.; Moutsopoulos, I.; Colom, B.; Han, S.; Calero-Nieto, F. J.; Göttgens, B.; Mohorianu, I.; Simons, B. D.; Alcolea, M.
10.1101/2021.02.19.431899 — cell biology — Posted on 2021-02-19
1208 The action of Con-ikot-ikot toxin on single AMPA-type glutamate receptors
Baranovic, J.; Braunbeck, S.; Zaki, N.; Minniberger, S.; Chebli, M.; Plested, A. J.
10.1101/2021.02.19.432041 — neuroscience — Posted on 2021-02-19
1211 Small molecule allosteric inhibitors of RORγt block Th17-dependent inflammation and associated gene expression in vivo.
Saenz, S. A.; Local, A.; Carr, T.; Shakya, A.; Koul, S.; Hu, H.; Chourb, L.; Stedman, J.; Malley, J.; DAgostino, L. A.; Shanmugasundaram, V.; Malona, J.; Schwartz, C. E.; Beebe, L.; Clements, M.; Rajaraman, G.; Cho, J.; Jiang, L.; Dubrovskiy, A.; Kreilein, M.; Shimanovich, R.; Hamann, L. G.; Escoubet, L.; Ellis, J. M.
10.1101/2021.02.19.431952 — immunology — Posted on 2021-02-19
1212 Predictive Coding Models for Pain Perception
Song, Y.; Yao, M.; Kemprecos, H.; byrne, a.; Xiao, Z.; Zhang, Q.; Singh, A.; Wang, J.; Chen, Z. S.
10.1101/843284 — neuroscience — Posted on 2021-02-19
1215 The molecular infrastructure of glutamatergic synapses in the mammalian forebrain
Peukes, J.; Lovatt, M.; Leistner, C.; Boulanger, J.; Morado, D. R.; Kukulski, W.; Zhu, F.; Komiyama, N. H.; Briggs, J. A. G.; Grant, S. G. N.; Frank, R. A. W.
10.1101/2021.02.19.432002 — neuroscience — Posted on 2021-02-19
1220 Prophage-encoded phage defence proteins with cognate self-immunity
Owen, S. V.; Wenner, N.; Dulberger, C. L.; Rodwell, E. V.; Bowers-Barnard, A.; Quinones-Olvera, N.; Rigden, D. J.; Rubin, E. J.; Garner, E. C.; Baym, M.; Hinton, J. C. D.
10.1101/2020.07.13.199331 — microbiology — Posted on 2021-02-19
1221 A Substantia Innominata-midbrain Circuit Controls a General Aggressive Response
Zhu, Z.; Ma, Q.; Miao, L.; Yang, H.; Pan, L.; Li, K.; Zhang, X.; Wu, J.; Hao, S.; Lin, S.; Ma, X.; Hao, Y.; Duan, S.; Yu, Y.-q.
10.1101/2020.04.22.047670 — neuroscience — Posted on 2021-02-19
1223 Invasive atypical non-typhoidal Salmonella in The Gambia
Kanteh, A.; Sesay, A. K.; Alikhan, N.-F.; Ikumapayi, U. N.; Salaudeen, R.; Manneh, J.; Olatunji, Y.-A.; Page, A. J.; Mackenzie, G.
10.1101/2021.02.18.431831 — genomics — Posted on 2021-02-19
1228 HuR -dependent SOD2 protein synthesis is an early adaptation of ovarian cancer cells in response to anchorage independence
Kim, Y. S.; Welles, J. E.; Tang, P. W.; Javed, Z.; Elhaw, A. T.; Mythreye, K.; Kimball, S. R.; Hempel, N.
10.1101/2021.02.19.432010 — cancer biology — Posted on 2021-02-19
1229 Droplet and fibril formation of the functional amyloid Orb2
Ashami, K.; Falk, A. S.; Hurd, C.; Garg, S.; Cervantes Cortes, S. A.; Rawat, A.; Siemer, A. B.
10.1101/2021.02.19.430336 — biophysics — Posted on 2021-02-19
1230 Theoretical basis for stabilizing messenger RNA through secondary structure design
Wayment-Steele, H. K.; Kim, D. S.; Choe, C. A.; Nicol, J. J.; Wellington-Oguri, R.; Watkins, A. M.; Parra Sparberg, R. A.; Huang, P.; Eterna Massive Open Laboratory, ; Das, R.
10.1101/2020.08.22.262931 — biophysics — Posted on 2021-02-19
1234 Tissue context determines the penetrance of regulatory DNA variation
Halow, J.; Byron, R.; Hogan, M. S.; Ordonez, R.; Groudine, M.; Bender, M. A.; Stamatoyannopoulos, J. A.; Maurano, M. T.
10.1101/2020.06.27.175422 — genomics — Posted on 2021-02-19
1235 Complex polyploid and hybrid species in an apomictic and sexual tropical forage grass group: genomic composition and evolution in Urochloa (Brachiaria) species
Tomaszewska, P.; Vorontsova, M. S.; Renvoize, S. A.; Ficinski, S. Z.; Tohme, J.; Schwarzacher, T.; Castiblanco, V.; de Vega, J. J.; Mitchell, R. A. C.; Heslop-Harrison, P.
10.1101/2021.02.19.431966 — genomics — Posted on 2021-02-19
1236 Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases
Ritchie, S. C.; Lambert, S. A.; Arnold, M.; Teo, S. M.; Lim, S.; Scepanovic, P.; Marten, J.; Zahid, S.; Chaffin, M.; Liu, Y.; Abraham, G.; Ouwehand, W. H.; Roberts, D. J.; Watkins, N. A.; Drew, B. G.; Calkin, A.; Di Angelantonio, E.; Soranzo, N.; Burgess, S.; Chapman, M.; Kathiresan, S.; Khera, A. V.; Danesh, J.; Butterworth, A. S.; Inouye, M.
10.1101/2019.12.14.876474 — genetics — Posted on 2021-02-19
1239 Notch-Jagged signaling complex defined by an interaction mosaic
Zeronian, M. R.; Klykov, O.; Portell i de Montserrat, J.; Konijnenberg, M. J.; Gaur, A.; Scheltema, R. A.; Janssen, B. J. C.
10.1101/2021.02.19.432005 — molecular biology — Posted on 2021-02-19
1240 Dimerisation of APOBEC1 is dispensable for its RNA/DNA editing activity and modulates its availability
Chieca, M.; Montini, M. D.; Severi, F.; Lembo, G.; Donati, F.; Pecori, R.; Conticello, S. G.
10.1101/410803 — molecular biology — Posted on 2021-02-19
1241 A simple pressure-assisted method for MicroED specimen preparation
Zhao, J.; Xu, H.; Lebrette, H.; Carroni, M.; Taberman, H.; Hogbom, M.; Zou, X.
10.1101/665448 — molecular biology — Posted on 2021-02-19
1242 Live cell imaging reveals that RecA finds homologous DNA by reduced dimensionality search
Wiktor, J.; Gynna, A. H.; Leroy, P.; Larsson, J.; Coceano, G.; Testa, I.; Elf, J.
10.1101/2020.02.13.946996 — microbiology — Posted on 2021-02-19
1243 Mosquito saliva sialokinin-dependent enhancement of arbovirus infection through endothelial barrier leakage
Lefteri, D.; Bryden, S.; Pingen, M.; Terry, S.; Beswick, E.; Georgiev, G.; Van Der Laan, M.; Mastrullo, V.; Campagnolo, P.; Waterhouse, R. M.; Varjak, M.; Merits, A.; Fragkoudis, R.; Griffin, S.; Pondeville, E.; McKimmie, C. S.
10.1101/2021.02.19.431961 — microbiology — Posted on 2021-02-19
1244 Recoding enhances the metabolic capabilities of two novel methylotrophic Asgardarchaeota lineages
Sun, J.; Evans, P. N.; Gagen, E. J.; Woodcroft, B. J.; Hedlund, B. P.; Woyke, T.; Hugenholtz, P.; Rinke, C.
10.1101/2021.02.19.431964 — microbiology — Posted on 2021-02-19
1245 Vesicular stomatitis virus chimeras expressing the Oropouche virus glycoproteins elicit protective immune responses in mice.
Stubbs, S. H.; Pontelli, M. C.; MISHRA, N.; Zhuo, C.; Souza, J. d. P.; Viana, R. M. M.; Lipkin, W. I. H.; Knipe, D.; Arruda, E. A.; Whelan, S. P. J.
10.1101/2021.02.19.432025 — microbiology — Posted on 2021-02-19
1247 Increased amphetamine-induced hyperactivity in translin (Tsn) KO mice is driven by elevated adiposity
Fu, X.; Shah, A. P.; Keighron, J.; Mou, T.-C. M.; Ladenheim, B.; Alt, J.; Fukudome, D.; Niwa, M.; Tamashiro, K.; Tanda, G.; Sawa, A.; Cadet, J.-L.; Rais, R.; Baraban, J. M.
10.1101/2020.10.08.331447 — neuroscience — Posted on 2021-02-19
1249 Hippocampal sharp wave-ripples and the associatedsequence replay emerge from structured synapticinteractions in a network model of area CA3
Ecker, A.; Bagi, B.; Vertes, E.; Steinbach-Nemeth, O.; Karlocai, M. R.; Papp, O. I.; Miklos, I.; Hajos, N.; Freund, T. F.; Gulyas, A. I.; Kali, S.
10.1101/2021.02.18.431868 — neuroscience — Posted on 2021-02-19
1250 Gut microbial taxa elevated by dietary sugar disrupt memory function
Noble, E. E.; Olson, C.; Davis, E. A.; Tsan, L.; Chen, Y.-W.; Schade, R.; Liu, C.; Suarez, A. N.; Jones, R. B.; de La Serre, C.; Yang, X.; Hsiao, E. Y.; Kanoski, S.
10.1101/2020.06.16.153809 — neuroscience — Posted on 2021-02-19
1252 Designing efficient genetic code expansion in Bacillus subtilis to gain biological insights
Stork, D. A.; Squyres, G. R.; Kuru, E.; Gromek, K. A.; Rittichier, J.; Jog, A.; Burton, B. M.; Church, G. M.; Garner, E. C.; Kunjapur, A. M.
10.1101/2021.02.19.432053 — synthetic biology — Posted on 2021-02-19
1254 Pregnancy and weaning regulate human maternal liver size and function
Bartlett, A. Q.; Vesco, K. K.; Purnell, J. Q.; Francisco, M.; Goddard, E.; DeBarber, A.; Leo, M. C.; Baetscher, E.; Rooney, W.; Naugler, W.; Guimaraes, A.; Catalano, P.; Schedin, P. J.
10.1101/2021.02.18.431862 — physiology — Posted on 2021-02-19
1255 An mRNA expression-based signature for oncogene-induced replication-stress
Guerrero, S.; Bhattacharya, A.; van der Vegt, B.; Everts, M.; Fehrmann, R.; van Vugt, M.
10.1101/2021.02.19.431930 — cancer biology — Posted on 2021-02-19
1256 Stromal architecture directs early dissemination in pancreatic ductal adenocarcinoma
Ray, A.; Callaway, M.; Rodriguez-Merced, N.; Crampton, A.; Carlson, M.; Emme, K.; Ensminger, E.; Kinne, A.; Schrope, J.; Rasmussen, H.; Jiang, H.; DeNardo, D.; Wood, D.; Provenzano, P.
10.1101/2021.02.19.431984 — cancer biology — Posted on 2021-02-19
1258 A catalogue of omics biological ageing clocks reveals substantial commonality and associations with disease risk
Macdonald-Dunlop, E.; Taba, N.; Klaric, L.; Frkatovic, A.; Walker, R.; Hayward, C.; Esko, T.; Haley, C.; Fischer, K.; Wilson, J. F.; Joshi, P. K.
10.1101/2021.02.01.429117 — bioinformatics — Posted on 2021-02-19
1260 Succinate is Broadly Tissue-Permeant and Uncouples Mitochondrial Respiration from ATP Synthesis
Hass, D. T.; Robbings, B. M.; Bisbach, C. M.; Giering, E.; Mundinger, T. O.; Sadilek, M.; Sweet, I. R.; Hurley, J. B.
10.1101/2021.02.10.430650 — biochemistry — Posted on 2021-02-19
1261 Collective detection based on visual information in animal groups
Davidson, J. D.; Sosna, M. M. G.; Twomey, C. R.; Sridhar, V. H.; Leblanc, S. P.; Couzin, I. D.
10.1101/2021.02.18.431380 — animal behavior and cognition — Posted on 2021-02-19
1262 RNA-binding proteins regulate aldosterone homeostasis in human steroidogenic cells
Fu, R.; Wellman, K.; Baldwin, A.; Rege, J.; Walters, K.; Hirsekorn, A.; Riemondy, K.; Rainey, W. E.; Mukherjee, N.
10.1101/2021.02.19.431050 — genomics — Posted on 2021-02-19
1263 Parallel Characterization of cis-Regulatory Elements for Multiple Genes UsingCRISPRpath
Ren, X.; Wang, M.; Li, B.; Jamieson, K.; Zheng, L.; Jones, I. R.; Li, B.; Takagi, M. A.; Lee, J.; Maliskova, L.; Tam, T. W.; Yu, M.; Hu, R.; Lee, L.; Abnousi, A.; Li, G.; Li, Y.; Hu, M.; Ren, B.; Wang, W.; Shen, Y.
10.1101/2021.02.19.431931 — genomics — Posted on 2021-02-19
1269 A Cas-BCAR3 co-regulatory circuit controls lamellipodia dynamics
Steenkiste, E. M.; Berndt, J. D.; Pilling, C.; Simpkins, C.; Cooper, J. A.
10.1101/2021.01.29.428899 — cell biology — Posted on 2021-02-19
1270 A single cell atlas of human teeth
Pagella, P.; De Vargas Roditi, L.; Stadlinger, B.; Moor, A. E.; Mitsiadis, T. A.
10.1101/2021.02.19.431962 — cell biology — Posted on 2021-02-19
1271 Rules for the self-assembly of ESCRT-III on endosomes
Sprenger, S.; Migliano, S. M.; Oleschko, F.; Kobald, M.; Hess, M. W.; Teis, D.
10.1101/2021.02.19.431979 — cell biology — Posted on 2021-02-19
1272 Recoding enhances the metabolic capabilities of two novel methylotrophic Asgardarchaeota lineages
Sun, J.; Evans, P. N.; Gagen, E. J.; Woodcroft, B. J.; Hedlund, B. P.; Woyke, T.; Hugenholtz, P.; Rinke, C.
10.1101/2021.02.19.431964 — microbiology — Posted on 2021-02-19
1273 A Protein A based Staphylococcus aureus vaccine with improved safety
Shi, M.; Chen, X.; Sun, Y.; Kim, H. K.; Schneewind, O.; Missiakas, D. M.
10.1101/2021.02.19.432007 — microbiology — Posted on 2021-02-19
1275 A novel mechanosensitive channel controls osmoregulation, differentiation and infectivity in Trypanosoma cruzi
Dave, N.; Cetiner, U.; Arroyo, D.; Fonbuena, J.; Tiwari, M.; Barrera, P.; Lander, N.; Anishkin, A.; Sukharev, S.; Jimenez, V.
10.1101/498469 — microbiology — Posted on 2021-02-19
1279 SMAD4 governs a feedforward regulation of the TGF-beta effects in CD8 T cells that contributes to preventing chronic intestinal inflammation
Igalouzene, R.; Hernandez-Vargas, H.; Benech, N.; Bauche, D.; Barrachina, C.; Dubois, E.; Marie, J. C.; SOUDJA, S. M.
10.1101/2021.02.19.431987 — immunology — Posted on 2021-02-19
1281 Adequate knowledge of COVID-19 impacts good practices amongst health profession students in the Philippines
Dalanon, J.; Redoble, R.; Belotindos, J.-A.; Delos Reyes, C.; Fabillar, J.; Armero, M. S.; Locsin, R.; Suzuki, Y.; Okura, K.; Matsuka, Y.
10.1101/2021.02.18.431919 — scientific communication and education — Posted on 2021-02-19
1282 TGF-B signaling suppresses TCA cycle metabolism in renal cancer.
Nam, H.; Kundu, A.; Karki, S.; Brinkley, G.; Chandrashekar, D. S.; Kirkman, R. L.; Liu, J.; Liberti, M. V.; Locasale, J. W.; Mitchell, T.; Varambally, S.; Sudarshan, S.
10.1101/2021.02.19.429599 — cancer biology — Posted on 2021-02-19
1283 Probing the SAM Binding Site of SARS-CoV-2 nsp14 in vitro Using SAM Competitive Inhibitors Guides Developing Selective bi-substrate Inhibitors
Devkota, K.; Schapira, M.; Perveen, S.; Khalili Yazdi, A.; Li, F.; Chau, I.; Ghiabi, P.; Hajian, T.; Loppnau, P.; Bolotokova, A.; Satchell, K. J.; Wang, K.; Li, D.; Liu, J.; Smil, D.; Luo, M.; Jin, J.; Fish, P. V.; Brown, P. J.; Vedadi, M.
10.1101/2021.02.19.424337 — biochemistry — Posted on 2021-02-19
1284 Delivery of recombinant SARS-CoV-2 envelope protein into human cells
Hutchison, J. M.; Capone, R.; Luu, D. D.; Hadziselimovic, A.; Van Horn, W. D.; Sanders, C. R.
10.1101/2021.02.18.431684 — biochemistry — Posted on 2021-02-19
1287 Viperin inhibits cholesterol biosynthesis and interacts with enzymes in the cholesterol biosynthetic pathway
Grunkemeyer, T. J.; Ghosh, S.; Patel, A. M.; Sajja, K.; Windak, J.; Basrur, V.; Kim, Y. S.; Nesvizhskii, A. I.; Kennedy, R. T.; Marsh, E. N. G.
10.1101/2021.02.19.431989 — biochemistry — Posted on 2021-02-19
1289 SARS-CoV-2 variant evolution in the United States: High accumulation of viral mutations over time likely through serial Founder Events and mutational bursts.
Tasakis, R. N.; Samaras, G.; Jamison, A.; Lee, M.; Paulus, A.; Whitehouse, G.; Verkoczy, L.; Papavasiliou, F. N.; Diaz, M.
10.1101/2021.02.19.431311 — genetics — Posted on 2021-02-19
1290 Antiviral activity of influenza A virus defective interfering particles against SARS-CoV-2 replication in vitro through stimulation of innate immunity
Rand, U.; Kupke, S. Y.; Shkarlet, H.; Hein, M. D.; Hirsch, T.; Marichal-Gallardo, P.; Cicin-Sain, L.; Reichl, U.; Bruder, D.
10.1101/2021.02.19.431972 — microbiology — Posted on 2021-02-19
1293 Dispersal syndromes affect ecosystem functioning in ciliate microcosms
Raffard, A.; Campana, J.; Legrand, D.; Schtickzelle, N.; Jacob, S.
10.1101/2021.02.19.431939 — ecology — Posted on 2021-02-19
1295 Extracellular riboflavin induces anaerobic biofilm formation in Shewanella oneidensis
Edel, M.; Sturm, G.; Sturm-Richter, K.; Wagner, M.; Novion Ducassou, J.; Coute, Y.; Horn, H.; Gescher, J.
10.1101/2021.02.19.431833 — microbiology — Posted on 2021-02-19
1299 The biosynthesis of phospholipids is linked to the cell cycle in a model eukaryote
Vitova, M.; Lanta, V.; Cizkova, M.; Jakubec, M.; Rise, F.; Halskau, O.; Bisova, K.; Furse, S.
10.1101/2021.02.19.431944 — systems biology — Posted on 2021-02-19
1300 Messages From the Small Intestine Carried by Extracellular Vesicles in Prediabetes: a Proteomic Portrait
Ferreira, I.; de Oliveira, R. M.; Carvalho, A. S.; Beck, H. C.; Matthiesen, R.; Silva, B. C.; Macedo, M. P.
10.1101/2021.02.19.431856 — pathology — Posted on 2021-02-19
1301 Selective MAP1LC3C (LC3C) autophagy requires noncanonical initiation regulators and the paralog-specific C-terminal peptide
Czyzyk-Krzeska, M. F.; Bischoff, M. E.; Zang, Y.; Chou, J.; Price, A. D.; Talbot, N. J.; Newbold, M. J.; Paul, A.; Guan, J.-L.; Plas, D. R.; Meller, J.
10.1101/2021.02.19.431861 — cancer biology — Posted on 2021-02-19
1304 Establishment of a human three-dimensional chip-based chondro-synovial co-culture joint model for reciprocal cross-talk studies in arthritis research
Rothbauer, M.; Byrne, R. A.; Schobesberger, S.; Olmos Calvo, I.; Fischer, A.; Reihs, E.; Spitz, S.; Bachmann, B. E. M.; Sevelda, F.; Holinka, J.; Holnthoner, W.; Redl, H.; Toegel, S.; Windhager, R.; Kiener, H. P.; Ertl, P.
10.1101/2021.02.19.431936 — bioengineering — Posted on 2021-02-19
1305 Genetic diversification of persistent Mycobacterium abscessus within Cystic Fibrosis patients
Lewin, A.; Kamal, E.; Semmler, T.; Winter, K.; Kaiser, S.; Schaefer, H.; Mao, L.; Eschenhagen, P.; Grehn, C.; Schwarz, C.
10.1101/2021.02.19.431934 — genomics — Posted on 2021-02-19
1306 Using Y-chromosome capture enrichment to resolve haplogroup H2 shows new evidence for a two-Path Neolithic expansion to Western Europe
Rohrlach, A. B.; Papac, L.; Childebayeva, A.; Rivollat, M.; Villalba-Mouco, V.; Neumann, G. U.; Penske, S.; Skourtanioti, E. B.; van de Loosdrecht, M.; Akar, M.; Boyadzhiev, K.; Boyadzhiev, Y.; Deguilloux, M.-F.; Dobes, M.; Erdal, Y. S.; Ernee, M.; Frangipane, M.; Furmanek, M.; Friederich, S.; Ghesquiere, E.; Haluszko, A.; Hansen, S.; Kuessner, M.; Mannino, M.; Oezbal, R.; Reinhold, S.; Rottier, S.; Salazar-Garcia, D. C.; Diaz, J. S.; Stockhammer, P. W.; de Togores Munoz, C. R.; Yener, K. A.; Posth, C.; Krause, J.; Herbig, A.; Haak, W.
10.1101/2021.02.19.431761 — genetics — Posted on 2021-02-19
1308 Aedes albopictus bionomics in Procida Island, a promising Mediterranean site for the assessment of innovative and community-based integrated pest management methods.
Caputo, B.; Langella, G.; Petrella, V.; Virgillito, C.; Manica, M.; Filipponi, F.; Varone, M.; Primo, P.; Puggioli, A.; Bellini, R.; D'Antonio, C.; Iesu, L.; Tullo, L.; Rizzo, C.; Longobardi, A.; Sollazzo, G.; Perrotta, M. M.; Fabozzi, M.; Palmieri, F.; Saccone, G.; Rosa, R.; della Torre, A.; Salvemini, M.
10.1101/2021.02.19.431954 — ecology — Posted on 2021-02-19
1312 Combined Metabolic Activators decrease liver steatosis by activating mitochondrial metabolism in a Golden Syrian hamster study
Yang, H.; Mayneris-Perxachs, J.; Boque, N.; Bas, J. M. d.; Arola, L.; Yuan, M.; Turkez, H.; Uhlen, M.; Boren, J.; Zhang, C.; Mardinoglu, A.; Caimari, A.
10.1101/2021.02.19.431968 — systems biology — Posted on 2021-02-19
1313 Predicting the zoonotic capacity of mammal species for SARS-CoV-2
Fischhoff, I. R.; Castellanos, A. A.; Rodrigues, J. P. G. L. M.; Varsani, A.; Han, B. A.
10.1101/2021.02.18.431844 — ecology — Posted on 2021-02-19
1315 ESC - a comprehensive resource for SARS-CoV-2 immune escape variants
Rophina, M.; Pandhare, K.; Shamnath, A.; Imran, M.; Jolly, B.; Scaria, V.
10.1101/2021.02.18.431922 — bioinformatics — Posted on 2021-02-19
1316 Insights into the secondary structural ensembles of the full SARS-CoV-2 RNA genome in infected cells
Lan, T. C. T.; Allan, M. F.; Malsick, L.; Khandwala, S.; Nyeo, S. S. Y.; Sun, Y.; Guo, J. U.; Bathe, M.; Griffiths, A.; Rouskin, S.
10.1101/2020.06.29.178343 — biochemistry — Posted on 2021-02-19
1321 Long SARS-CoV-2 nucleocapsid sequences in blood monocytes collected soon after hospital admission
Pagano, N.; Laurent-Rolle, M.; Hsu, J. C.; Yale IMPACT Research Team, ; Vogels, C. B.; Grubaugh, N. D.; Manuelidis, L.
10.1101/2020.12.16.423113 — microbiology — Posted on 2021-02-19
1323 Constructing An Adult Orofacial Premotor Atlas In Allen Mouse CCF
Takatoh, J.; Park, J. H.; Lu, J.; Li, S.; Thompson, P. M.; Han, B.-X.; Zhao, S.; Kleinfeld, D.; Friedman, B.; Wang, F.
10.1101/2021.02.18.431923 — neuroscience — Posted on 2021-02-19
1324 Analysis of motor unit spike trains estimated from high-density surface electromyography is highly reliable across operators
Hug, F.; Avrillon, S.; Del Vecchio, A.; Casolo, A.; Ibanez, J.; Nuccio, S.; Rossato, J.; Holobar, A.; Farina, D.
10.1101/2021.02.19.431376 — neuroscience — Posted on 2021-02-19
1325 Somatic hypomethylation of pericentromeric SST1 repeats and tetraploidization in human colorectal cancer cells
Gonzalez, B.; Navarro-Jimenez, M.; Alonso-De Gennaro, M. J.; Jansen, S. M.; Granada, I.; Perucho, M.; Alonso, S.
10.1101/2021.02.19.431645 — cancer biology — Posted on 2021-02-19
1328 Deep Learning-Based Approaches for Decoding Motor Intent from Peripheral Nerve Signals
Luu, D. K.; Nguyen, A. T.; Jiang, M.; Xu, J.; Drealan, M. W.; Cheng, J.; Keefer, E. W.; Zhao, Q.; Yang, Z.
10.1101/2021.02.18.431483 — bioengineering — Posted on 2021-02-19
1330 ClusterMap: multi-scale clustering analysis of spatial gene expression
He, Y.; Tang, X.; Huang, J.; Zhou, H.; Chen, K.; Liu, A.; Ren, J.; Shi, H.; Lin, Z.; Li, Q.; Aditham, A.; Shu, J.; Liu, J.; Wang, X.
10.1101/2021.02.18.431337 — genomics — Posted on 2021-02-19
1333 Light and noise pollution impacts specialist wildlife species disproportionately
Ditmer, M. A.; Francis, C. D.; Barber, J. R.; Stoner, D. C.; Seymoure, B. M.; Fristrup, K. M.; Carter, N. H.
10.1101/2021.02.18.431905 — ecology — Posted on 2021-02-19
1336 A comparative analysis of SARS-CoV-2 antivirals in human airway models characterizes 3CLpro inhibitor PF-00835231 as a potential new treatment for COVID-19
de Vries, M.; Mohamed, A.; Prescott, R. A.; Valero-Jimenez, A.; Desvignes, L.; O'Connor, R.; Steppan, C.; Devlin, J. C.; Ivanova, E.; Herrera, A.; Schinlever, A.; Loose, P.; Ruggles, K.; Koralov, S.; Anderson, A.; Binder, J.; Dittmann, M.
10.1101/2020.08.28.272880 — microbiology — Posted on 2021-02-19
1337 West Nile virus in crocodiles and mosquitoes in Zimbabwe
Roy, M.; Mufunda, F.; Slawski, D.; Mutswiri, C.; Mvere, I.; Slawski, K.; Kelly, P.; Bezuidenhout, A.; Piras, I.; Hanyire, T.; Markey, B.; Barry, G.
10.1101/2021.02.19.431612 — microbiology — Posted on 2021-02-19
1338 Analysis of the blood microbiome in a porcine model of fecal-induced peritonitis
Hyun, H.; Lee, M. S.; Park, I.; Ko, H. S.; Yun, S.; Jang, D.-H.; Kim, S.; Kim, H.; Kang, J. H.; Lee, J. H.; Kwon, T.
10.1101/2021.02.18.431914 — microbiology — Posted on 2021-02-19
1339 Development and validation of a miniaturized host range screening assay for bacteriophages
Ng, R. N.; Grey, L. J.; Vaitekenas, A.; McLean, S. A.; Laucirica, D. R.; Poh, M. W.-P.; Hillas, J.; Winslow, S. G.; Iszatt, J. J.; Iosifidis, T.; Tai, A. S.; Agudelo-Romero, P.; Chang, B. J.; Stick, S. M.; Kicic, A.
10.1101/2021.02.18.431904 — microbiology — Posted on 2021-02-19
1342 CO2 supply modulates lipid remodelling, photosynthetic and respiratory activities in Chlorella species
Cecchin, M.; Paloschi, M.; Busnardo, G.; Cazzaniga, S.; Cuine, S.; Li-Beisson, Y.; Wobbe, L.; Ballottari, M.
10.1101/2021.02.18.431842 — plant biology — Posted on 2021-02-19
1343 PEAK3 pseudokinase represents a pro-migratory and -invasive signalling scaffold
Hou, J.; Nguyen, E. V.; Surudoi, M.; Roy, M. J.; Patel, O.; Lucet, I. S.; Ma, X.; Daly, R. J.
10.1101/2021.02.17.431740 — cancer biology — Posted on 2021-02-19
1344 CK2 phosphorylation of human papillomavirus 16 E2 on serine 23 promotes interaction with TopBP1 and is critical for E2 plasmid retention function
Morgan, I. M.; Prabhakar, A. T.; James, C. D.; Das, D.; Otoa, R.; Day, M.; Burgner, J. W.; Fontan, C. T.; Wang, X.; Wieland, A.; Donaldson, M. M.; Bristol, M. L.; Li, R.; Oliver, A.; Pearl, L. H.; Smith, B. O.
10.1101/2021.02.17.431757 — molecular biology — Posted on 2021-02-19
1345 Host-virus chimeric events in SARS-CoV2 infected cells are infrequent and artifactual
Yan, B.; Chakravorty, S.; Mirabelli, C.; Wang, L.; Trujillo-Ochoa, J. L.; Chauss, D.; Kumar, D.; Lionakis, M. S.; Olson, M. R.; Wobus, C. E.; Afzali, B.; Kazemian, M.
10.1101/2021.02.17.431704 — microbiology — Posted on 2021-02-19
1347 The trypanosome UDP-glucose pyrophosphorylase is imported by piggybacking into glycosomes where unconventional sugar nucleotide synthesis takes place
Villafraz, O.; Baudouin, H.; Mazet, M.; Kulyk, H.; Dupuy, J.-W.; Pineda, E.; Botte, C. Y.; Inaoka, D.; Portais, J.-C.; Bringaud, F.
10.1101/2021.02.17.431754 — microbiology — Posted on 2021-02-19
1348 A whole-brain imaging-based systems approach to understand origin of addiction in binge-like drinking model
Stefaniuk, M.; Monika, P.; Klaudia, N.; Baranski, M.; Zielinski, Z.; Bijoch, Łukasz; Legutko, D.; Majka, P.; Bednarek, S.; Jermakow, N.; Wojcik, D.; Kaczmarek, L.
10.1101/2021.02.17.431586 — neuroscience — Posted on 2021-02-19
1349 Systematic Phenotyping and Characterization of the 5xFAD mouse model of Alzheimer's Disease
Forner, S.; Kawauchi, S.; Balderrama-Gutierrez, G.; Kramar, E. A.; Matheos, D. P.; Phan, J.; Javonillo, D. I.; Minh Tran, K.; Hingco, E.; da Cunha, C.; Rezaie, N.; Alcantara, J. A.; Baglietto-Vargas, D.; Jansen, C.; Neumann, J.; Wood, M. A.; MacGregor, G. R.; Mortazavi, A.; Tenner, A. J.; LaFerla, F. M.; Green, K. N.
10.1101/2021.02.17.431716 — neuroscience — Posted on 2021-02-19
1355 ATLASx: a computational map for the exploration of biochemical space
Mohammadi-Peyhani, H.; Hafner, J.; Sveshnikova, A.; Viterbo, V.; Hatzimanikatis, V.
10.1101/2021.02.17.431583 — biochemistry — Posted on 2021-02-19
1356 Drosophila glue protects from predation
Borne, F.; Prigent, S. R.; Molet, M.; Courtier-Orgogozo, V.
10.1101/2020.12.23.424162 — evolutionary biology — Posted on 2021-02-19
1357 Fetal estrogens are not involved in sex determination but critical for early ovarian differentiation.
Jolivet, G.; Daniel-Carlier, N.; Harscoet, E.; Airaud, E.; Dewaele, A.; Pierson, C.; Giton, F.; Boulanger, L.; Daniel, N.; Mandon-Pepin, B.; Pannetier, M.; Pailhoux, E.
10.1101/2020.12.13.419770 — developmental biology — Posted on 2021-02-19
1360 A small RNA is linking CRISPR-Cas and zinc transport
Märkle, P.; Maier, L.-K.; Maass, S.; Hirschfeld, C.; Bartel, J.; Becher, D.; Voss, B.; Marchfelder, A.
10.1101/2021.02.19.431937 — molecular biology — Posted on 2021-02-19
1361 Spatially confined sub-tumor microenvironments orchestrate pancreatic cancer pathobiology
Grünwald, B. T.; Devisme, A.; Andrieux, G.; Vyas, F.; Aliar, K.; McCloskey, C. W.; Macklin, A.; Jang, G. H.; Denroche, R.; Romero, J. M.; Bavi, P.; Bronsert, P.; Notta, F.; O'Kane, G.; Wilson, J.; Knox, J.; Tamblyn, L.; Radulovich, N.; Fischer, S. E.; Boerries, M.; Gallinger, S.; Kislinger, T. R.; Khokha, R.
10.1101/2021.02.18.431890 — cancer biology — Posted on 2021-02-19
1362 Glioblastoma remodeling of neural circuits in the human brain decreases survival
Krishna, S.; Choudhury, A.; Seo, K.; Ni, L.; Kakaizada, S.; Lee, A.; Aabedi, A.; Cao, C.; Sudharshan, R.; Egladyous, A.; Almeida, N.; Venkatesh, H.; Findlay, A.; Nagarajan, S.; Raleigh, D.; Brang, D.; Monje, M.; Hervey-Jumper, S.
10.1101/2021.02.18.431915 — cancer biology — Posted on 2021-02-19
1364 A Guide to Pre-Processing High-Throughput Animal Tracking Data
Gupte, P. R.; Beardsworth, C. E.; Spiegel, O.; Lourie, E.; Toledo, S.; Nathan, R.; Bijleveld, A. I.
10.1101/2020.12.15.422876 — ecology — Posted on 2021-02-19
1371 Induction of specific antibodies, IgG-secreting plasmablasts and memory B cells following BCG vaccination
Bitencourt, J.; Wilkie, M.; Peralta Alvarez, M. P.; Jacobs, A.; Wright, D.; Harris, S. A.; Smith, S. G.; Elias, S.; White, A.; Sharpe, S.; O'Shea, M. K.; McShane, H.; Tanner, R.
10.1101/2021.02.18.431837 — immunology — Posted on 2021-02-18
1372 Cellular, Circuit and Transcriptional Framework for Modulation of Itch in the Central Amygdala
Samineni, V. K.; Grajales-Reyes, J.; Grajales-Reyes, G. E.; Tycksen, E.; Copits, B.; Pedersen, C.; Ankudey, E.; Sackey, J. N.; Sewell, S. B.; Bruchas, M. R.; Gereau, R. W.
10.1101/2021.02.18.431884 — neuroscience — Posted on 2021-02-18
1374 Impact of immediate cryopreservation on the establishment of patient derived xenografts from head and neck cancer patients.
Abel, L.; Durmaz, A.; Hu, R.; Longhurst, C.; Baschnagel, A. M.; Wheeler, D. L.; Scott, J. G.; Kimple, R. J.
10.1101/2020.02.03.930891 — cancer biology — Posted on 2021-02-18
1376 Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases
Korsunsky, I.; Wei, K.; Pohin, M.; Kim, E. Y.; Barone, F.; Kang, J. B.; Friedrich, M.; Turner, J.; Nayar, S.; Fisher, B. A.; Raza, K.; Marshall, J. L.; Croft, A. P.; Sholl, L. M.; Vivero, M.; Rosas, I. O.; Bowman, S. J.; Coles, M.; Frei, A. P.; Lassen, K.; Filer, A.; Powrie, F.; Buckley, C. D.; Brenner, M. B.; Raychaudhuri, S.
10.1101/2021.01.11.426253 — genomics — Posted on 2021-02-18
1377 Social network architecture and the tempo of cumulative cultural evolution
Cantor, M.; Chimento, M.; Smeele, S. Q.; He, P.; Papageorgiou, D.; Aplin, L. M.; Farine, D. R.
10.1101/2020.12.04.411934 — evolutionary biology — Posted on 2021-02-18
1379 Influenza-specific effector memory B cells predict long-lived antibody responses to vaccination in humans
Nellore, A.; Zumaquero, E.; Scharer, C. D.; King, R. G.; Tipton, C. M.; Fucile, C.; Mousseau, B.; Bradley, J. E.; Mi, T.; Goepfert, P. A.; Kearney, J. F.; Boss, J. M.; Randall, T. D.; Sanz, I.; Rosenberg, A.; Lund, F. E.
10.1101/643973 — immunology — Posted on 2021-02-18
1380 Functional cooperativity mediated by rationally selected combinations of human monoclonal antibodies targeting the henipavirus receptor binding protein
Doyle, M. P.; Kose, N.; Borisevich, V.; Binshtein, E.; Amaya, M.; Nagel, M.; Annand, E. J.; Armstrong, E.; Bombardi, R.; Dong, J.; Schey, K. L.; Broder, C. C.; Zeitlin, L.; Kuang, E.; Bornholdt, Z.; West, B.; Geisbert, T. W.; Cross, R. W.; Crowe, J. E.
10.1101/2021.02.17.431743 — immunology — Posted on 2021-02-18
1381 Reduced inhibition in depression impairs stimulus processing in human cortical microcircuits
Yao, H. K.; Guet-McCreight, A.; Mazza, F.; Moradi Chameh, H.; Prevot, T. D.; Griffiths, J.; Tripathy, S. J.; Valiante, T. A.; Sibille, E.; Hay, E.
10.1101/2021.02.17.431698 — neuroscience — Posted on 2021-02-18
1382 Brain network motifs are markers of loss and recovery of consciousness
Duclos, C.; Nadin, D.; Mahdid, Y.; Tarnal, V.; Picton, P.; Vanini, G.; Golmirzaie, G.; Janke, E.; Avidan, M. S.; Kelz, M. B.; Mashour, G. A.; Blain-Moraes, S.
10.1101/2020.03.16.993659 — neuroscience — Posted on 2021-02-18
1384 Redefining colorectal cancer classification and clinical stratification through a single-cell atlas
Khaliq, A. M.; kurt, z.; Grunvald, M. W.; Erdogan, C.; Turgut, S. S.; Rand, T.; Khare, S.; Borgia, J. A.; Hayden, D. M.; Pappas, S. G.; Govekar, H. R.; Bhama, A. R.; Singh, A.; Jacobson, R. A.; Kam, A. E.; Zloza, A.; Reiser, J.; Catenacci, D. V.; Turaga, K.; Radovich, M.; Thyparambil, S.; Levy, M. A.; Subramanian, J.; Kuzel, T. M.; Sadanandam, A.; Hussain, A.; El-Rayes, B.; Salahudeen, A.; Masood, A.
10.1101/2021.02.02.429256 — cancer biology — Posted on 2021-02-18
1387 Variational autoencoders learn universal latent representations of metabolomics data
Gomari, D. P.; Schweickart, A.; Cerchietti, L.; Paietta, E.; Fernandez, H.; Al-Amin, H.; Suhre, K.; Krumsiek, J.
10.1101/2021.01.14.426721 — bioinformatics — Posted on 2021-02-18
1390 Massive colonization of protein-coding exons by selfish genetic elements in Paramecium germline genomes
Sellis, D.; Guerin, F.; Arnaiz, O.; Pett, W.; Lerat, E.; Boggetto, N.; Krenek, S.; Berendonk, T.; Couloux, A.; Aury, J.-M.; Labadie, K.; Malinski, S.; Meyer, E.; Sperling, L.; Duret, L.; Duharcourt, S.
10.1101/2020.12.23.424184 — genomics — Posted on 2021-02-18
1391 Bridging the gap: Using reservoir ecology and human serosurveys to estimate Lassa virus spillover in West Africa
Basinski, A. J.; Fichet-Calvet, E. J.; Sjodin, A. R.; Varrelman, T. J.; Remien, C.; Layman, N. C.; Bird, B. H.; Wolking, D. J.; Monagin, C.; Ghersi, B. M.; Barry, P. A.; Jarvis, M. A.; Gessler, P. E.; Nuismer, S. L.
10.1101/2020.03.05.979658 — ecology — Posted on 2021-02-18
1393 New multiscale characterisation methodology for effective determination of isolation-structure-function relationship of extracellular vesicles.
Phan, T. H.; Divakarla, K. S.; Yeo, J. H.; Lei, Q.; Tharkar, P.; Pansani, T. N.; Leslie, K. G.; Tong, M.; Coleman, V. A.; Jamting, A.; Plessis, M.-D. D.; New, E. J.; Kalionis, B.; Demokritou, P.; Woo, H.-K.; Cho, Y.-K.; Chrzanowski, W.
10.1101/2021.02.09.430523 — cell biology — Posted on 2021-02-18
1395 The organizational principles of de-differentiated topographic maps
Liu, P.; Chrysidou, A.; Doehler, J.; Hebart, M.; Wolbers, T.; Kuehn, E.
10.1101/2020.07.08.179978 — neuroscience — Posted on 2021-02-18
1397 Environmental enrichment mitigates stroke-induced change in sharp-wave associated ripple characteristics
Ip, Z. T.; Rabiller, G.; He, J.-W.; Chavan, S.; Nishijima, Y.; Akamatsu, Y.; Liu, J.; Yazdan-Shahmorad, A.
10.1101/2021.02.12.431002 — neuroscience — Posted on 2021-02-18
1400 Design of novel CV-N variants: Modulation of binding dynamics through distal mutations
Kazan, I. C.; Sharma, P.; Bobkov, A. A.; Fromme, R.; Ghirlanda, G.; Ozkan, S. B.
10.1101/2020.12.21.423842 — biophysics — Posted on 2021-02-18
1402 Conservation and convergence of genetic architecture in the adaptive radiation of Anolis lizards
McGlothlin, J. W.; Kobiela, M. E.; Wright, H. V.; Kolbe, J. J.; Losos, J. B.; Brodie, E. D.
10.1101/2021.02.18.431064 — evolutionary biology — Posted on 2021-02-18
1403 Inferring genome-wide correlations of mutation fitness effects between populations
Huang, X.; Fortier, A. L.; Coffman, A. J.; Struck, T. J.; Irby, M. N.; James, J. E.; Burguette, J. E.; Ragsdale, A. P.; Gutenkunst, R. N.
10.1101/703918 — evolutionary biology — Posted on 2021-02-18
1404 A signalling axis involving CNOT3, Aurora B and ERK promotes differentiation and survival of mesendodermal progenitor cells
Sarkar, M.; Martufi, M.; Roman-Trufero, M.; Wang, Y.-F.; Whilding, C.; Dormann, D.; Sabbattini, P.; Dillon, N.
10.1101/756932 — developmental biology — Posted on 2021-02-18
1406 A genetic program boosts mitochondrial function to power macrophage tissue invasion
Emtenani, S.; Martin, E. T.; Gyoergy, A.; Bicher, J.; Wendelin-Genger, J.; Koecher, T.; Hurd, T.; Bergthaler, A.; Rangan, P.; Siekhaus, D. E.
10.1101/2021.02.18.431643 — cell biology — Posted on 2021-02-18
1408 Probing cortical excitability under GABAergic modulation
Lepeu, G.; Van Maren, E.; Slabeva, K.; Fuchs, M.; Anso, J.; Z'Graggen, W.; Pollo, C.; Schindler, K.; Adamantidis, A.; Baud, M. O.
10.1101/2021.02.18.431873 — neuroscience — Posted on 2021-02-18
1413 Pregnancy and weaning regulate human maternal liver size and function
Bartlett, A. Q.; Francisco, M.; Goddard, E.; DeBarber, A.; Leo, M. C.; Baetscher, E.; Rooney, W.; Naugler, W.; Catalano, P.; Guimaraes, A.; Purnell, J. Q.; Vesco, K. K.; Schedin, P. J.
10.1101/2021.02.18.431862 — physiology — Posted on 2021-02-18
1414 Physiological and ecological consequences of the water optical properties degradation on reef corals
Lopez-Londono, T.; Galindo-Martinez, C. T.; Gomez-Campo, K.; Gonzalez-Guerrero, L. A.; Roitman, S.; Pollock, F. J.; Pizarro, V.; Lopez-Victoria, M.; Medina, M.; Iglesias-Prieto, R.
10.1101/2021.02.18.431834 — physiology — Posted on 2021-02-18
1420 Theobroma cacao improves bone growth by modulating defective ciliogenesis in a mouse model of achondroplasia
MARTIN, L.; KACI, N.; BENOIST-LASSELIN, C.; MONDOLONI, M.; DECAUDAVEINE, S.; ESTIBALS, V.; CORNILLE, M.; LOISAY, L.; FLIPO, J.; DEMUYNCK, B.; DE LA LUZ CADIZ-GURREA, M.; BARBAULT, F.; FERNANDEZ-ARROYO, S.; SCHIBLER, L.; SEGURA-CARRETERO, A.; DAMBROISE, E.; LEGEAI-MALLET, L.
10.1101/2021.02.18.431801 — developmental biology — Posted on 2021-02-18
1421 ChEC-seq: a robust method to identify protein-DNA interactions genome-wide
Bruzzone, M. J.; Albert, B.; Hafner, L.; Kubik, S.; Lezaja, A.; Mattarocci, S.; Shore, D. M.
10.1101/2021.02.18.431798 — molecular biology — Posted on 2021-02-18
1422 A glimpse into the diverse cellular immunity against SARS-CoV-2
Chang, L.-J.; Chang, C.-W.; Liu, Y.; Jiao, C.; Liu, H.; Chen, X.
10.1101/2021.02.17.431750 — microbiology — Posted on 2021-02-18
1423 SARS-CoV-2 nucleocapsid protein dually regulates innate immune responses
Zhao, Y.; Sui, L.; Wu, P.; Wang, W.; Tan, G.; Wang, Z.; Yu, Y.; Hou, Z.; Wang, G.; Liu, Q.
10.1101/2021.02.17.431755 — microbiology — Posted on 2021-02-18
1424 Meta-analysis of orthogonal OMICs data from COVID-19 patients unveils prognostic markers and antiviral factors.
Biji, A.; Swaraj, S.; Khatun, O.; Narayan, R.; Sardar, R.; Satish, D.; Mehta, S.; Bindhu, H.; Jeevan, M.; Saini, D. K.; Singh, A.; Gupta, D.; Tripathi, S.
10.1101/2021.02.18.431825 — microbiology — Posted on 2021-02-18
1427 Homologous and heterologous serological response to the N-terminal domain of SARS-CoV-2
Lv, H.; Tsang, O. T.-Y.; So, R. T. Y.; Wang, Y.; Liu, H.; Yip, G. K.; Teo, Q. W.; Lin, Y.; Liang, W.; Wang, J.; Ng, W. W.; Wilson, I. A.; Peiris, M.; Wu, N. C.; Mok, C. K. P.
10.1101/2021.02.17.431722 — immunology — Posted on 2021-02-18
1428 Brain endothelial CXCL12 attracts protective Natural Killer cells during ischemic stroke
Wang, S.; de Fabritus, L.; Ashok Kumar, P.; Werner, Y.; Siret, C.; Simic, M.; Kerdiles, Y. M.; Stumm, R.; van de Pavert, S. A.
10.1101/2021.02.18.431426 — immunology — Posted on 2021-02-18
1432 Characterization and tissue localization of zebrafish homologs of the human ABCB1 multidrug transporter
Robey, R. W.; Robinson, A. N.; Ali-Rahmani, F.; Huff, L. M.; Lusvarghi, S.; Vahedi, S.; Hotz, J. M.; Warner, A. C.; Butcher, D.; Matta, J.; Edmondson, E. F.; Lee, T. D.; Roth, J. S.; Lee, O. W.; Shen, M.; Tanner, K. D.; Hall, M. D.; Ambudkar, S. V.; Gottesman, M. M.
10.1101/2021.02.18.431829 — pharmacology and toxicology — Posted on 2021-02-18
1433 Engineering the Immune Adaptor Protein STING as a Biologic
Sun, X.; Ni, Y.; He, Y.; Yang, M.; Tani, T.; Kitajima, S.; Barbie, D. A.; Li, J.
10.1101/2021.02.18.431824 — bioengineering — Posted on 2021-02-18
1434 Familial prion disease-related mutation E196K displays a novel amyloid fibril structure revealed by cryo-EM
Wang, L.-Q.; Zhao, K.; Yuan, H.-Y.; Li, X.-N.; Dang, H.-B.; Ma, Y.; Wang, Q.; Wang, C.; Sun, Y.; Chen, J.; Li, D.; Zhang, D.; Yin, P.; Liu, C.; Liang, Y.
10.1101/2021.02.18.431846 — biochemistry — Posted on 2021-02-18
1435 Isolation and characterisation of bacteriophages with activity against invasive non-typhoidal Salmonella causing bloodstream infection in Malawi
Rodwell, E. V.; Wenner, N.; Pulford, C. V.; Cai, Y.; Bowers-Barnard, A.; Beckett, A.; Rigby, J.; Picton, D. M.; Blower, T. R.; Feasey, N. A.; Hinton, J. C. D.; Perez-Sepulveda, B. M.
10.1101/2021.02.18.431836 — microbiology — Posted on 2021-02-18
1436 A Combination Adjuvant for the Induction of Potent Antiviral Immune Responses for a Recombinant SARS-CoV-2 Protein Vaccine
Jangra, S.; Landers, J. J.; Rathnasinghe, R.; O'Konek, J. J.; Janczak, K. W.; Cascalho, M.; Kennedy, A. A.; Tai, A. W.; Baker, J. R.; Schotsaert, M.; Wong, P. T.
10.1101/2021.02.18.431484 — immunology — Posted on 2021-02-18
1441 Invasive atypical non-typhoidal Salmonella in The Gambia
Kanteh, A.; Sesay, A. K.; Alikhan, N.-F.; Ikumapayi, U. N.; Salaudeen, R.; Manneh, J.; Olatunji, Y.-A.; Page, A. J.; Mackenzie, G.
10.1101/2021.02.18.431831 — genomics — Posted on 2021-02-18
1445 Rotavirus susceptibility of antibiotic-treated mice ascribed to diminished expression of interleukin-22
Schnepf, D.; Hernandez, P.; Mahlakoiv, T.; Crotta, S.; Sullender, M. E.; Peterson, S. T.; Ohnemus, A.; Michiels, C.; Gentle, I.; Dumoutier, L.; Reis, C. A.; Diefenbach, A.; Wack, A.; Baldridge, M. T.; Staeheli, P.
10.1101/2021.02.18.431818 — immunology — Posted on 2021-02-18
1447 Optogenetic silencing of neurotransmitter release with a naturally occurring invertebrate rhodopsin
Mahn, M.; Saraf-Sinik, I.; Patil, P.; Pulin, M.; Bitton, E.; Karalis, N.; Bruentgens, F.; Palgi, S.; Gat, A.; Dine, J.; Wietek, J.; Davidi, I.; Levy, R.; Litvin, A.; Zhou, F.; Sauter, K.; Soba, P.; Schmitz, D.; Luthi, A.; Rost, B. R.; Wiegert, J. S.; Yizhar, O.
10.1101/2021.02.18.431673 — neuroscience — Posted on 2021-02-18
1450 Retrograde Control of Cytosolic Translation Targets Synthesis of Plastid Localized Proteins and Nuclear Responses for Efficient Light Acclimation.
Moore, M.; Smith, A. B.; Wesemann, C.; Schmidtpott, S.; Wegener, M.; Farooq, M. A.; Seidel, T.; Pogson, B. J.; Dietz, K.-J.
10.1101/2021.02.18.431817 — plant biology — Posted on 2021-02-18
1456 Fetal gut colonization: meconium does not have a detectable microbiota before birth
Kennedy, K.; Gerlach, M. J.; Adam, T.; Heimesaat, M. M.; Rossi, L.; Surette, M. G.; Sloboda, D. M.; Braun, T.
10.1101/2021.02.17.431710 — microbiology — Posted on 2021-02-18
1458 Hippocampal sharp wave-ripples and the associatedsequence replay emerge from structured synapticinteractions in a network model of area CA3
Ecker, A.; Bagi, B.; Vertes, E.; Steinbach-Nemeth, O.; Karlocai, M. R.; Papp, O.; Miklos, I.; Hajos, N.; Freund, T.; Gulyas, A. I.; Kali, S.
10.1101/2021.02.18.431868 — neuroscience — Posted on 2021-02-18
1460 The heart rate discrimination task: a psychophysical method to estimate the accuracy and precision of interoceptive beliefs
Legrand, N.; Nikolova, N.; Correa, C.; Braendholt, M.; Stuckert, A.; Kildahl, N.; Vejlo, M.; Fardo, F.; Allen, M.
10.1101/2021.02.18.431871 — neuroscience — Posted on 2021-02-18
1461 Genome-wide approaches for the identification of markers and genes associated with sugarcane yellow leaf virus resistance
Pimenta, R. J. G.; Aono, A. H.; Villavicencio, R. C. B.; Coutinho, A. E.; da Silva, C. C.; dos Anjos, I. A.; Perecin, D.; Landell, M. G. d. A.; Goncalves, M. C.; Pinto, L. R.; de Souza, A. P.
10.1101/2020.09.04.283614 — plant biology — Posted on 2021-02-18
1469 Discovery of photosynthesis genes through whole-genome sequencing of acetate-requiring mutants of Chlamydomonas reinhardtii
Wakao, S.; Shih, P. M.; Guan, K.; Schackwitz, W.; Ye, J.; Shih, R.; Chovatia, M.; Sharma, A.; Martin, J.; Wei, C.-L.; Niyogi, K. K.
10.1101/2021.02.17.431526 — plant biology — Posted on 2021-02-18
1470 Carotenoid and tocopherol fortification of zucchini fruits using a viral RNA vector
Houhou, F.; Cordero, T.; Aragones, V.; Marti, M.; Cebolla-Cornejo, J.; Perez de Castro, A.; Rodriguez-Concepcion, M.; Pico, B.; Daros, J.-A.
10.1101/2021.02.18.431807 — plant biology — Posted on 2021-02-18
1472 Celecoxib exhibits therapeutic potential in experimental model of hyperlipidaemia
Ekor, M.; Owusu Agyei, P. E.; Obese, E.; Biney, R. P.; Henneh, I. T.; Antwi-Adjei, M.; Yahaya, E. S.; Amoakohene, G.; Akakpo, P. K.
10.1101/2021.02.15.431245 — pharmacology and toxicology — Posted on 2021-02-18
1478 Joint inference of species histories and gene flow
Mueller, N. F.; Ogilvie, H.; Zhang, C.; Fontaine, M. C.; Amaya-Romero, J. E.; Drummond, A.; Stadler, T.
10.1101/348391 — evolutionary biology — Posted on 2021-02-18
1480 Distinct Phenotypes of SARS-CoV-2 Isolates Reveal Viral Traits Critical for Replication in Primary Human Respiratory Cells
Pohl, M. O.; Busnadiego, I.; Kufner, V.; Glas, I.; Karakus, U.; Schmutz, S.; Zaheri, M.; Abela, I.; Trkola, A.; Huber, M.; Stertz, S.; Hale, B. G.
10.1101/2020.10.22.350207 — microbiology — Posted on 2021-02-18
1481 Direct activation of endothelial cells by SARS-CoV-2 nucleocapsid protein is blocked by Simvastatin
Qian, Y.; Lei, T.; Patel, P.; Lee, C.; Monaghan-Nichols, P.; Xin, H.-B.; Qiu, J.; Fu, M.
10.1101/2021.02.14.431174 — immunology — Posted on 2021-02-18
1482 The functions of SARS-CoV-2 neutralizing and infection-enhancing antibodies in vitro and in mice and nonhuman primates
Li, D.; Edwards, R. J.; Manne, K.; Martinez, D. R.; Schafer, A.; Alam, S. M.; Wiehe, K.; Lu, X.; Parks, R.; Sutherland, L. L.; Oguin, T. H.; McDanal, C.; Perez, L. G.; Mansouri, K.; Gobeil, S. M. C.; Janowska, K.; Stalls, V.; Kopp, M.; Cai, F.; Lee, E.; Foulger, A.; Hernandez, G.; Sanzone, A.; Tilahun, K.; Jiang, C.; Tse, L. V.; Bock, K. W.; Minai, M.; Nagata, B. M.; Cronin, K.; Gee-Lai, V.; Deyton, M.; Barr, M.; Von Holle, T.; Macintyre, A. N.; Stover, E.; Feldman, J.; Hauser, B. M.; Caradonna, T. M.; Scobey, T. D.; Moody, M. A.; Cain, D. W.; DeMarco, C. T.; Denny, T. N.; Woods, C. W.; Petzol
10.1101/2020.12.31.424729 — immunology — Posted on 2021-02-18
1489 Resolving the Interactions Between Class 3 Semaphorin Receptors in Live Cells
Christie, S. M.; Hao, J.; Tracy, E.; Buck, M.; Yu, J. S.; Smith, A. W.
10.1101/2021.02.18.431813 — biophysics — Posted on 2021-02-18
1490 The cryo-EM structure of the neurofibromin dimer reveals the molecular basis for von Recklinghausen disease
Lupton, C. J.; Bayly-Jones, C.; D'Andrea, L.; Huang, C.; Schittenhelm, R. B.; Venugopal, H.; Whisstock, J. C.; Halls, M. L.; Ellisdon, A. M.
10.1101/2021.02.18.431788 — biochemistry — Posted on 2021-02-18
1491 Protein and substrate flexibility contribute to enzymatic specificity in human and bacterial methionine adenosyltransferases
GADE, M. H.; Tan, L. L.; Sandhu, M.; Brock, J. S.; Delaney, A.; Villar-Briones, A.; Jackson, C. J.; Laurino, P.
10.1101/2021.02.18.431797 — biochemistry — Posted on 2021-02-18
1495 Integration of differential gene expression with weighted gene correlation network analysis identifies genes whose expression is remodeled throughout physiological aging in mouse tissues
Ferreira, M.; Francisco, S.; Soares, A. R.; Nobre, A.; Pinheiro, M.; Reis, A.; Neto, S.; Rodrigues, A. J.; Sousa, N.; Moura, G.; Santos, M. A. S.
10.1101/2021.02.18.431793 — genetics — Posted on 2021-02-18
1499 Pyrazinamide action is driven by the cell envelope stress response in Mycobacterium tuberculosis
Thiede, J. M.; Dillon, N.; Howe, M. D.; Modlin, S. J.; Aflakpui, R.; Hoffner, S.; Valafar, F.; Minato, Y.; Baughn, A. D.
10.1101/2021.02.17.431758 — microbiology — Posted on 2021-02-18
1500 Indoleamine 2,3-dioxygenase upregulates PD-1 expression on ovarian tumor infiltrating CD8+ T cells via kynurenine activation of the aryl hydrocarbon receptor
Amobi-McCloud, A.; MUTHUSWAMY, R.; Battaglia, S.; Yu, H.; Liu, T.; Wang, J.; Putluri, V.; Singh, P. K.; Qian, F.; Huang, R.-Y.; Putluri, N.; Takemasa, T.; Lugade, A.; Liu, S.; Odunsi, K.
10.1101/2021.02.18.431473 — immunology — Posted on 2021-02-18
1501 Evolving a new efficient mode of fructose utilization for improved bioproduction in Corynebacterium glutamicum
Krahn, I.; Bonder, D.; Torregrosa, L.; Stoppel, D.; Krause, J. P.; Meiswinkel, T. M.; Rosenfeldt, N.; Seibold, G. M.; Wendisch, V. F. N.; Lindner, S. N.
10.1101/2021.02.18.431779 — synthetic biology — Posted on 2021-02-18
1502 Integrating genomics and multi-platform metabolomics enables metabolite QTL detection in breeding-relevant apple germplasm
Bilbrey, E. A.; Williamson, K.; Hatzakis, E.; Doud Miller, D.; Fresnedo Ramirez, J.; Cooperstone, J. L.
10.1101/2021.02.18.431481 — plant biology — Posted on 2021-02-18
1503 Structural basis of drug recognition by the multidrug transporter ABCG2
Kowal, J.; Ni, D.; Jackson, S.; Manolaridis, I.; Stahlberg, H.; Locher, K. P.
10.1101/2021.02.18.431786 — biophysics — Posted on 2021-02-18
1507 A covalently crosslinked bioink for multi-materials drop-on-demand 3D bioprinting of three-dimensional cell cultures
Utama, R. H.; Tan, V.; Tjandra, K. C.; Sexton, A.; Nguyen, D.; O'Mahony, A. P.; Ribeiro, J. C. C.; Kavallaris, M.; Gooding, J. J.
10.1101/2021.02.18.431759 — bioengineering — Posted on 2021-02-18
1508 Collective detection based on visual information in animal groups
Davidson, J. D.; Sosna, M. M. G.; Twomey, C. R.; Sridhar, V. H.; Leblanc, S. P.; Couzin, I. D.
10.1101/2021.02.18.431380 — animal behavior and cognition — Posted on 2021-02-18
1511 Competence-associated peptide BriC alters fatty acid biosynthesis in Streptococcus pneumoniae
Aggarwal, S. D.; Gullett, J. M.; Fedder, T.; Safi, J. P. F.; Rock, C. O.; Hiller, N. L.
10.1101/2021.02.17.431746 — microbiology — Posted on 2021-02-18
1512 Fluorescence Imaging-Based Discovery of Membrane Domain-Associated Proteins in Mycobacterium smegmatis
Rokicki, C. A. Z.; Brenner, J. R.; Dills, A. H.; Judd, J. J.; Kester, J. C.; Puffal, J.; Wade, J. T.; Gray, T. A.; Derbyshire, K. M.; Fortune, S.; Morita, Y. S.
10.1101/2021.02.17.431749 — microbiology — Posted on 2021-02-18
1514 A D-2-hydroxyglutarate biosensor based on specific transcriptional regulator DhdR
Xiao, D.; Zhang, W.; Guo, X.; Liu, Y.; Hu, C.; Guo, S.; Kang, Z.; Xu, X.; Ma, C.; Gao, C.; Xu, P.
10.1101/2021.02.18.430539 — microbiology — Posted on 2021-02-18
1518 Genome-wide insights into population structure and host specificity of Campylobacter jejuni
Epping, L.; Walther, B.; Piro, R. M.; Knüver, M.-T.; Huber, C.; Thürmer, A.; Flieger, A.; Fruth, A.; Janecko, N.; Wieler, L. H.; Stingl, K.; Semmler, T.
10.1101/2021.02.18.431648 — genomics — Posted on 2021-02-18
1522 Harmonised segmentation of neonatal brain MRI
Grigorescu, I.; Vanes, L.; Uus, A.; Batalle, D.; Cordero-Grande, L.; Nosarti, C.; Edwards, D.; Hajnal, J.; Modat, M.; Deprez, M.
10.1101/2021.02.17.431611 — neuroscience — Posted on 2021-02-18
1528 Reduced inhibition in depression impairs stimulus processing in human cortical microcircuits
Yao, H. K.; Guet-McCreight, A.; Mazza, F.; Moradi Chameh, H.; Prevot, T. D.; Griffiths, J.; Tripathy, S. J.; Valiante, T. A.; Sibille, E.; Hay, E.
10.1101/2021.02.17.431698 — neuroscience — Posted on 2021-02-18
1529 Twitches emerge postnatally during quiet sleep in human infants and are synchronized with sleep spindles
Sokoloff, G.; Dooley, J. C.; Glanz, R. M.; Wen, R. Y.; Hickerson, M. M.; Evans, L. G.; Laughlin, H. M.; Apfelbaum, K. S.; Blumberg, M. S.
10.1101/2021.02.17.431688 — neuroscience — Posted on 2021-02-18
1530 Fasting reverses drug-resistance in hepatocellular carcinoma through p53-dependent metabolic synergism
Krstic, J.; Reinisch, I.; Schindlmaier, K.; Galhuber, M.; Berger, N.; Kupper, N.; Moyschewitz, E.; Auer, M.; Michenthaler, H.; Noessing, C.; Depaoli, M. R.; Ramadani-Muja, J.; Stryeck, S.; Pichler, M.; Rinner, B.; Deutsch, A. J.; Reinisch, A.; Madl, T.; Zenezini Chiozzi, R.; Heck, A. J.; Huch, M.; Malli, R.; Prokesch, A.
10.1101/2021.02.10.430545 — cancer biology — Posted on 2021-02-18
1534 Glycine receptor α3K governs mobility and conductance of L/K splice variant heteropentamers
Lemmens, V.; Thevelein, B.; Kankowski, S.; Mizuno, H.; Meier, J.; Rocha, S.; Brone, B.; Hendrix, J.
10.1101/2021.02.18.431627 — biochemistry — Posted on 2021-02-18
1537 Kinesin-6 Klp9 orchestrates spindle elongation by regulating microtubule sliding and growth
Krüger, L. K.; Gelin, M.; Ji, L.; Kikuti, C.; Houdusse, A.; Thery, M.; Blanchoin, L.; Tran, P.
10.1101/2021.02.17.431708 — cell biology — Posted on 2021-02-18
1538 Intra-ocular dendritic cells are increased in HLA-B27 associated acute anterior uveitis
Kasper, M.; Heming, M.; Schafflick, D.; Li, X.; Lautwein, T.; Meyer zu Horste, M.; Bauer, D.; Walscheid, K.; Wiendl, H.; Loser, K.; Heiligenhaus, A.; Meyer zu Hörste, G.
10.1101/2021.02.16.431370 — immunology — Posted on 2021-02-18
1540 The underlying mechanisms of improved balance after one and ten sessions of balance training in older adults
Alizadehsaravi, L.; Koster, R. A. J.; Muijres, W.; Maas, H.; Bruijn, S. M.; van Dieen, J. H.
10.1101/2020.10.01.322313 — neuroscience — Posted on 2021-02-18
1541 Phase-based cortical synchrony is affected by prematurity
Yrjölä, P.; Stjerna, S.; Palva, J. M.; Vanhatalo, S.; Tokariev, A.
10.1101/2021.02.15.431226 — neuroscience — Posted on 2021-02-18
1542 Universal latent axes capturing Parkinson's patient deep phenotypic variation reveals patients with a high genetic risk for Alzheimer's disease are more likely to develop a more aggressive form of Parkinson's.
Sandor, C.; Millin, S.; Dahl, A.; Lawton, M.; Hubbard, L.; Bojovic, B.; Peyret-Guzzon, M.; Matten, H.; Blancher, C.; Williams, N.; Ben-Shlomo, Y.; Hu, M. T.; Grosset, D. G.; Marchini, J.; Webber, C.
10.1101/655217 — neuroscience — Posted on 2021-02-18
1545 Timing of selective basal ganglia white matter loss in Huntington's disease
Zeun, P.; McColgan, P.; Dhollander, T.; Gregory, S.; Johnson, E. B.; Papoutsi, M.; Nair, A.; Scahill, R. I.; Rees, G.; Tabrizi, S. J.
10.1101/2021.02.17.431568 — neuroscience — Posted on 2021-02-18
1551 High-throughput and high-efficiency sample preparation for single-cell proteomics using a nested nanowell chip
Woo, J.; Williams, S. M.; Aguilera-Vazquez, V.; Sontag, R. L.; Moore, R. J.; Markillie, L. M.; Mehta, H. S.; Cantlon, J.; Adkins, J. N.; Smith, R. D.; Clair, G. C.; Pasa-Tolic, L.; Zhu, Y.
10.1101/2021.02.17.431689 — systems biology — Posted on 2021-02-18
1554 Chloroplast acquisition without the gene transfer in kleptoplastic sea slugs, Plakobranchus ocellatus
Maeda, T.; Takahashi, S.; Yoshida, T.; Shimamura, S.; Takaki, Y.; Nagai, Y.; Toyoda, A.; Suzuki, Y.; Arimoto, A.; Ishii, H.; Satoh, N.; Nishiyama, T.; Hasebe, M.; Maruyama, T.; Minagawa, J.; Obokata, J.; Shigenobu, S.
10.1101/2020.06.16.155838 — evolutionary biology — Posted on 2021-02-18
1557 Intrinsically disordered protein biosensor tracks the physical-chemical effects of osmotic stress on cells
Cuevas-Velazquez, C. L.; Vellosillo, T.; Guadalupe, K.; Schmidt, H. B.; Yu, F.; Moses, D.; Brophy, J. A.; Cosio-Acosta, D.; Das, A.; Wang, L.; Jones, A. M.; Covarrubias, A. A.; Sukenik, S.; Dinneny, J. R.
10.1101/2021.02.17.431712 — cell biology — Posted on 2021-02-18
1561 Unifying the known and unknown microbial coding sequence space
Vanni, C.; Schechter, M. S.; Acinas, S.; Barberan, A.; Buttigieg, P. L.; Casamayor, E. O.; Delmont, T. O.; Duarte, C. M.; Eren, A. M.; Finn, R. D.; Kottmann, R.; Mitchell, A.; Sanchez, P.; Siren, K.; Steinegger, M.; Glöckner, F. O.; Fernandez-Guerra, A.
10.1101/2020.06.30.180448 — microbiology — Posted on 2021-02-18
1562 Talaromyces marneffei promotes M2 polarization of human macrophages by downregulating SOCS3 expression and activating TLR9 pathway
Wei, W.; Ning, C.; Huang, J.; Wang, G.; Lai, J.; Han, J.; Zang, N.; Liang, B.; Liao, Y.; Le, T.; Jiang, J.; Ye, L.; Liang, H.
10.1101/2021.02.17.431726 — microbiology — Posted on 2021-02-18
1563 Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave
Hohsfield, L. A.; Najafi, A. R.; Ghorbanian, Y.; Soni, N.; Crapser, J.; Figueroa Velez, D. X.; Jiang, S.; Royer, S. E.; Kim, S. J.; Anderson, A.; Gandhi, S. P.; Mortazavi, A.; Inlay, M. A.; Green, K. N.
10.1101/2021.02.17.431594 — immunology — Posted on 2021-02-18
1564 Functional cooperativity mediated by rationally selected combinations of human monoclonal antibodies targeting the henipavirus receptor binding protein
Doyle, M. P.; Kose, N.; Borisevich, V.; Binshtein, E.; Amaya, M.; Nagel, M.; Annand, E. J.; Armstrong, E.; Bombardi, R.; Dong, J.; Schey, K. L.; Broder, C. C.; Zeitlin, L.; Kuang, E.; Bornholdt, Z.; West, B.; Geisbert, T. W.; Cross, R. W.; Crowe, J. E.
10.1101/2021.02.17.431743 — immunology — Posted on 2021-02-18
1569 Hot days are associated with short-term adrenocortical responses in a Southern African arid-zone passerine bird.
Moagi, L. L.; Bourne, A. R.; Cunningham, S. J.; Jansen, R.; Ngcamphalala, C. A.; Ridley, A. R.; McKechnie, A. E.
10.1101/2021.02.17.431578 — physiology — Posted on 2021-02-18
1570 Pharmacological inhibition of PAI-1 alleviates cardiopulmonary pathologies induced by exposure to air pollutants PM2.5
Ghosh, A. K.; Soberanes, S.; Lux, E.; Shang, M.; Piseaux Aillon, R.; Eren, M.; Budinger, G. R. S.; Miyata, T.; Vaughan, D. E.
10.1101/2021.02.17.431681 — pharmacology and toxicology — Posted on 2021-02-18
1577 Chromatin accessibility regulates intron retention in a cell type-specific manner
Petrova, V.; Song, R.; DEEP Consortium, ; Nordstrom, K. J. V.; Walter, J.; Wong, J. J.- L.; Armstrong, N. J.; Rasko, J. J. E.; Schmitz, U.
10.1101/2021.02.17.431609 — bioinformatics — Posted on 2021-02-18
1581 A Programmable Toolkit to Dynamically Signal Cells using Peptide Strand Displacement
Riker, K.; Daly, M. L.; Papanikolas, M.; Jian, T.; Klawa, S. J.; Sahin, J. S.; Liu, D.; Singh, A.; Miller, A. G.; Freeman, R.
10.1101/2021.02.17.431719 — bioengineering — Posted on 2021-02-18
1583 Quantifying Viscous Damping and Stiffness in Parkinsonism Using Data-Driven Model Estimation
Werning, A.; Umbarila, D.; Fite, M.; Fergus, S.; Zhang, J.; Molnar, G. F.; Johnson, L. A.; Wang, J.; Vitek, J. L.; Escobar Sanabria, D.
10.1101/2021.02.17.431730 — bioengineering — Posted on 2021-02-18
1585 Doublecortin engages the microtubule lattice through a cooperative binding mode involving its C- terminal domain
Rafiei, A.; Lee, L.; Crowder, D. A.; Saltzberg, D. J.; Sali, A.; Brouhard, G.; Schriemer, D. C.
10.1101/2021.02.17.431714 — biochemistry — Posted on 2021-02-18
1586 ATLASx: a computational map for the exploration of biochemical space
Mohammadi-Peyhani, H.; Hafner, J.; Sveshnikova, A.; Viterbo, V.; Hatzimanikatis, V.
10.1101/2021.02.17.431583 — biochemistry — Posted on 2021-02-18
1587 Genomic architecture of 5S rDNA cluster and its variations within and between species
Ding, Q.; Li, R.; Ren, X.; Chan, L.-y.; Ho, V. W.; Xie, D.; Ye, P.; Zhao, Z.
10.1101/2021.02.17.431734 — genomics — Posted on 2021-02-18
1588 Non-destructive extraction of DNA from preserved tissues in medical collections
Rayo, E.; Ferrari, G.; Neukamm, J.; Akgül, G.; Breidenstein, A. M.; Cooke, M.; Phillips, C.; Bouwman, A. S.; Rühli, F. J.; Schünemann, V. J.
10.1101/2021.02.17.431618 — genetics — Posted on 2021-02-18
1591 Dopamine receptor DOP-1 engages a sleep pathway to modulate swimming in C. elegans
Xu, Y.; Zhang, L.; Liu, Y.; Topalidou, I.; Hassinan, C.; Ailion, M.; Zhao, Z.; Wang, T.; Chen, Z.; Bai, J.
10.1101/2021.02.17.431715 — genetics — Posted on 2021-02-18
1597 Skillful prediction of tropical Pacific fisheries provided by Atlantic Ninos
Gomara, I.; Rodriguez-Fonseca, B.; Mohino, E.; Losada, T.; Polo, I.; Coll, M.
10.1101/2021.02.17.431587 — ecology — Posted on 2021-02-18
1598 Humans hastened the range collapse and extinction of woolly mammoth
Fordham, D. A.; Brown, S. C.; Akcakaya, H. R.; Brook, B. W.; Haythorne, S.; Manica, A.; Shoemaker, K. T.; Austin, J. J.; Blonder, B.; Pilowsky, J.; Rahbek, C.; Nogues-Bravo, D.
10.1101/2021.02.17.431706 — ecology — Posted on 2021-02-18
1600 Human breast milk enhances intestinal mucosal barrier function and innate immunity in a pediatric human enteroid model
Noel, G.; In, J.; Lemme-Dumit, J. M.; DeVine, L. R.; Cole, R. N.; Guerrerio, A. L.; Kovbasnjuk, O.; Pasetti, M. F.
10.1101/2021.02.17.431653 — immunology — Posted on 2021-02-18
1601 Goal-Driven Recurrent Neural Network Models of the Ventral Visual Stream
Nayebi, A.; Sagastuy-Brena, J.; Bear, D. M.; Kar, K.; Kubilius, J.; Ganguli, S.; Sussillo, D.; DiCarlo, J. J.; Yamins, D. L. K.
10.1101/2021.02.17.431717 — neuroscience — Posted on 2021-02-18
1606 Invariant Differential Expression Analysis Reveals Mechanism of Cancer Resistance to Cell Cycle Inhibitors
Chatterjee, A.; Pandey, S.; Danda, R.; Kumar R, R.; S, M.; Khetan, V.; Rishi, P.; S, R.; Elchuri, S. V.; Sahoo, D.
10.1101/2021.02.17.431607 — systems biology — Posted on 2021-02-17
1607 Dynamic Methylome Modification associated with mutational signatures in ageing and etiology of disease
Kumar, G.; Krishnasamy, K.; Pasha, N.; Nagarajan, N.; Mam, B.; Kishinani, M.; Vohra, V.; Jain, R.; Morawala Patell, V.
10.1101/2020.12.22.423778 — genomics — Posted on 2021-02-17
1609 Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells
Le Vasseur, M.; Friedman, J. R.; Jost, M.; Xu, J.; Yamada, J.; Kampmann, M.; Horlbeck, M. A.; Salemi, M. R.; Phinney, B. S.; Weissman, J. S.; Nunnari, J.
10.1101/2021.02.16.431450 — cell biology — Posted on 2021-02-17
1612 A transient postnatal quiescent period precedes emergence of mature cortical dynamics
Dominguez, S.; Ma, L.; Yu, H.; Pouchelon, G.; Mayer, C.; Spyropoulos, G. D.; Cea, C.; Buzsaki, G.; Fishell, G.; Khodagholy, D.; Gelinas, J. N.
10.1101/2021.02.17.430487 — neuroscience — Posted on 2021-02-17
1618 Music-selective neural populations arise without musical training
Boebinger, D. L.; Norman-Haignere, S. V.; McDermott, J. H.; Kanwisher, N.
10.1101/2020.01.10.902189 — neuroscience — Posted on 2021-02-17
1620 Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: the Multi-Targeting Drug DREAM Challenge
Xiong, Z.; Jeon, M.; Allaway, R. J.; Kang, J.; Park, D.; Lee, J.; Jeon, H.; Ko, M.; Jiang, H.; Zheng, M.; Tan, A. C.; Guo, X.; The Multi-Targeting Drug DREAM Challenge Community, ; Dang, K. K.; Tropsha, A.; Hecht, C.; Das, T. K.; Carlson, H. A.; Abagyan, R.; Guinney, J.; Schlessinger, A.; Cagan, R.
10.1101/2021.02.15.430538 — pharmacology and toxicology — Posted on 2021-02-17
1621 Time Trend, Social Vulnerability, and Identification of Risk Areas for Tuberculosis in Brazil: an Ecological Study
DE paiva, J. P. S.; Magalhaes, M. A. F. M.; LEAL, T. c.; DA SILVA, L. F.; DA SILVA, L. G.; DO CARMO, R. F.; Souza, C. D. F.
10.1101/2021.02.17.431602 — pathology — Posted on 2021-02-17
1622 Gene expression profiling of skeletal muscles
Alto, S. I.; Chang, C.-N.; Brown, K.; Kioussi, C.; Filtz, T. M.
10.1101/2021.02.17.431599 — bioinformatics — Posted on 2021-02-17
1623 Measuring the unknown: an estimator and simulation study for assessing case reporting during epidemics
Jarvis, C.; Gimma, A.; Finger, F.; Morris, T.; Thompson, J.; le Polain de Warroux, O.; Edmunds, J.; Funk, S.; Jombart, T.
10.1101/2021.02.17.431606 — bioinformatics — Posted on 2021-02-17
1625 Chromosome-length genome assembly and structural variations of the primal Basenji dog (Canis lupus familiaris) genome
Edwards, R. J.; Field, M. A. J.; Ferguson, J. M.; Dudchenko, O.; Keilwagen, J.; Rosen, B. D.; Johnson, G. S.; Rice, E. S.; Hillier, L.; Hammond, J. M.; Tomwarnicki, S. G.; Omer, A.; Skvortsova, K.; Bogdanovic, O.; Zammit, R. A.; Aiden, E. L.; Warren, W. C.; Ballard, J. W. O.
10.1101/2020.11.11.379073 — genomics — Posted on 2021-02-17
1628 GATA3 is essential for separating patterning domains during facial morphogenesis
Abe, M.; Firulli, A. B.; Kanai, S. M.; Limi, K.-C.; Engel, J. D.; Clouthier, D. E.
10.1101/2021.02.17.431667 — developmental biology — Posted on 2021-02-17
1629 Mitochondrial phenotypes in purified human immune cell subtypes and cell mixtures
Rausser, S.; Trumpff, C.; McGill, M. A.; Junker, A.; Wang, W.; Ho, S.-H.; Mitchell, A.; Karan, K. R.; Monk, C.; Segerstrom, S. C.; Reed, R. G.; Picard, M.
10.1101/2020.10.16.342923 — cell biology — Posted on 2021-02-17
1634 Dynamic predictive coding across the left fronto-temporal language hierarchy: Evidence from MEG, EEG and fMRI
Wang, L.; Schoot, L.; Brothers, T.; Alexander, E.; Warnke, L.; Kim, M.; Khan, S.; Hamalainen, M.; Kuperberg, G.
10.1101/2021.02.17.431452 — neuroscience — Posted on 2021-02-17
1638 The Amyloid Precursor Protein regulates human cortical neurogenesis
Shabani, K.; Pigeon, J.; Benaissa Touil Zariouh, M.; Liu, T.; Saffarian, A.; Komatsu, J.; Liu, E.; Danda, N.; Limame, R.; Bohl, D.; Parras, C.; Hassan, B. A.
10.1101/2021.02.17.431707 — developmental biology — Posted on 2021-02-17
1641 Targeting Diacylglycerol Lipase to Reduce AlcoholConsumption
Bedse, G.; Winters, N. D.; Astafyev, A.; Patrick, T. A.; Mahajan, V. R.; Uddin, M. J.; Centanni, S. W.; Samuels, D. C.; Marnett, L. J.; Winder, D. G.; Patel, S.
10.1101/2021.02.16.431429 — neuroscience — Posted on 2021-02-17
1643 Eukaryotic translation initiation factor 2A protects pancreatic beta cells during endoplasmic reticulum stress while rescuing translation inhibition.
Panzhinskiy, E.; Skovso, S.; Cen, H. H.; Chu, K. Y.; MacDonald, K.; Soukhatcheva, G.; Dionne, D. A.; Hallmaier-Wacker, L. K.; Wildi, J. S.; Marcil, S.; Noursadeghi, N.; Taghizadeh, F.; Verchere, C. B.; Jan, E.; Johnson, J. D.
10.1101/2021.02.17.431676 — physiology — Posted on 2021-02-17
1644 The Serine Protease HtrA2 mediates radiation-induced senescence in cancer cells
Hammer, L.; Levin-Salomon, V.; Yaeli-Slonim, N.; Weiss, M.; Dekel-Bird, N. P.; Olender, T.; Porat, Z.; Winograd-Katz, S.; Savidor, A.; Levin, Y.; Bialik, S.; Geiger, B.; Kimchi, A.
10.1101/2021.02.17.431668 — cancer biology — Posted on 2021-02-17
1646 Traditional use of Cissampelos pareira L. for hormone disorder and fever provides molecular links of ESR1 modulation to viral inhibition
Haider, M.; Dholakia, D.; Panwar, A.; Garg, P.; Anand, V.; Gheware, A. P.; Singhal, K.; Singh, D.; Burse, S. A.; Enayathullah, M. G.; Parekh, Y.; Ram, S.; Kumari, S.; Kumar, A.; Ray, A.; Medigeshi, G. R.; Bokara, K. K.; Sharma, U.; Prasher, B.; Mukerji, M.
10.1101/2021.02.17.431579 — genomics — Posted on 2021-02-17
1649 Mechanical stress determines morphogenesis and cell ordering in confined bacterial biofilms
Zhang, Q.; Li, J.; Nijjer, J.; Lu, H.; Kothari, M.; Alert, R.; Cohen, T.; Yan, J.
10.1101/2021.02.17.431682 — microbiology — Posted on 2021-02-17
1650 The MS remyelinating drug bexarotene (an RXR agonist) promotes induction of human Tregs and suppresses Th17 differentiation in vitro
Gaunt, C. M.; Rainbow, D.; MacKenzie, R.; Jarvis, L.; Mousa, H.; Cunniffe, N.; Georgieva, Z.; Brown, W.; Coles, A.; Jones, J. L.
10.1101/2021.02.17.431344 — immunology — Posted on 2021-02-17
1652 Diversity and Function of Motile Ciliated Cell Types within Ependymal Lineages of the Zebrafish Brain
D'Gama, P. P.; Qiu, T.; Cosacak, M. I.; Chong, Y. L.; Konac, A.; Hansen, J. N.; Ringers, C.; Hui, S. P.; Olstad, E. W.; Ng, C. P.; Rayamajhi, D.; Wachten, D. N.; Liebl, D.; Kikuchi, K.; Kizil, C.; Yaksi, E.; Roy, S.; Jurisch-Yaksi, N.
10.1101/2021.02.17.431442 — neuroscience — Posted on 2021-02-17
1653 Affinity Requirements For Control Of Synaptic Targeting And Neuronal Cell Survival By Heterophilic IgSF Cell Adhesion Molecules
Xu, S.; Sergeeva, A. P.; Katsamba, P. S.; Mannepalli, S.; Bahna, F.; Bimela, J.; Zipursky, L. S.; Shapiro, L.; Honig, B.; Zinn, K.
10.1101/2021.02.16.431482 — neuroscience — Posted on 2021-02-17
1655 Ezh2 as an epigenetic checkpoint regulator during monocyte differentiation: a potential target to improve cardiac repair after myocardial infarction
Rondeaux, J.; Groussard, D.; Renet, S.; Tardif, V.; Dumesnil, A.; Chu, A.; Henry, J.-P.; Badji, Z.; Claire, V.; Beziau, D.; Guerrot, D.; Brand, M.; Richard, V.; Durand, E.; Brakenhielm, E.; Fraineau, S.
10.1101/2021.02.17.428828 — physiology — Posted on 2021-02-17
1658 How the replication and transcription complex of SARS-CoV-2 functions in leader-to-body fusion
Li, X.; Zhao, Q.; Chang, J.; Duan, G.; Bei, J.; Yau, T. O.; Yang, J.; Ruan, J.; He, B.; Shan, G.
10.1101/2021.02.17.431652 — bioinformatics — Posted on 2021-02-17
1659 Multiple Sites on SARS-CoV-2 Spike Protein are Susceptible to Proteolysis by Cathepsins B, K, L, S, and V
Bollavaram, K.; Leeman, T.; Kulkarni, A.; Upshaw, S.; Lee, M.; Yang, J.; Song, H.; Platt, M. O.
10.1101/2021.02.17.431617 — bioengineering — Posted on 2021-02-17
1660 Structural basis for the specificity of PPM1H phosphatase for Rab GTPases
Waschbüsch, D.; Berndsen, K.; Knebel, A.; Alessi, D. R.; Khan, A. R.
10.1101/2021.02.17.431620 — biochemistry — Posted on 2021-02-17
1661 A cell atlas of chromatin accessibility across 25 adult human tissues
Zhang, K.; Hocker, J. D.; Miller, M.; Hou, X.; Chiou, J.; Poirion, O. B.; Qiu, Y.; Li, Y. E.; Gaulton, K. J.; Wang, A.; Preissl, S.; Ren, B.
10.1101/2021.02.17.431699 — genomics — Posted on 2021-02-17
1662 A comprehensive fitness landscape model reveals the evolutionary history and future evolvability of eukaryotic cis-regulatory DNA sequences
Vaishnav, E. D.; de Boer, C. G.; Yassour, M.; Molinet, J.; Fan, L.; Adiconis, X.; Thompson, D. A.; Cubillos, F. A.; Levin, J. Z.; Regev, A.
10.1101/2021.02.17.430503 — genomics — Posted on 2021-02-17
1665 HES1 protein oscillations are necessary for neural stem cells to exit from quiescence
Marinopoulou, E.; Sabherwal, N.; Biga, V.; Desai, J.; Adamson, A. D.; Papalopulu, N.
10.1101/2021.02.17.431655 — cell biology — Posted on 2021-02-17
1666 Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants
Yuan, M.; Huang, D.; Lee, C.-C. D.; Wu, N. C.; Jackson, A. M.; Zhu, X.; Liu, H.; Peng, L.; van Gils, M. J.; Sanders, R. W.; Burton, D. R.; Reincke, S. M.; Prüss, H.; Kreye, J.; Nemazee, D.; Ward, A. B.; Wilson, I. A.
10.1101/2021.02.16.430500 — microbiology — Posted on 2021-02-17
1668 SARS-CoV-2 vaccination induces neutralizing antibodies against pandemic and pre-emergent SARS-related coronaviruses in monkeys
Saunders, K. O.; Lee, E.; Parks, R.; Martinez, D. R.; Li, D.; Chen, H.; Edwards, R. J.; Gobeil, S. M. C.; Barr, M.; Mansouri, K.; Alam, S. M.; Sutherland, L. L.; Cai, F.; Sanzone, A.; Berry, M.; Manne, K.; Kapingidza, A. B.; Azoitei, M.; Tse, L. V.; Scobey, T. D.; Spreng, R.; Rountree, R. W.; DeMarco, C. T.; Denny, T. N.; Woods, C. W.; Petzold, E. W.; Oguin, T. H.; Sempowski, G. D.; Gagne, M.; Douek, D. C.; Tomai, M. A.; Fox, C. B.; Seder, R.; Wiehe, K.; Weissman, D.; Pardi, N.; Acharya, P.; Andersen, H.; Lewis, M. G.; Moore, I. N.; Montefiori, D. C.; Baric, R. S.; Haynes, B. F.
10.1101/2021.02.17.431492 — immunology — Posted on 2021-02-17
1669 Delayed induction of type I and III interferons and nasal epithelial cell permissiveness to SARS-CoV-2
Hatton, C. F.; Botting, R. A.; Duenas, M. E.; Haq, I. J.; Verdon, B.; Thompson, B. J.; Stremenova Spegarova, J.; Gothe, F.; Stephenson, E. A.; Gardner, A. I.; Murphy, S.; Scott, J.; Garnett, J. P.; Carrie, S.; Hussain, R.; Coxhead, J.; Davey, T.; Simpson, J.; Haniffa, M.; Hambleton, S.; Brodlie, M.; Ward, C.; Trost, M.; Reynolds, G.; Duncan, C. J. A.
10.1101/2021.02.17.431591 — immunology — Posted on 2021-02-17
1670 Phospholipid peroxidation fuels ExoU phospholipase-dependent cell necrosis and supports Pseudomonas aeruginosa-driven pathology
Bagayoko, S.; Leon-Icaza, S.-A.; Pinilla, M.; Hessel, A.; Santoni, K.; Bordignon, P.-J.; Moreau, F.; Eren, E.; Boyance, A.; Naser, E.; Lefevre, L.; Berrone, C.; Iacobachvili, N.; Metais, A.; Rombouts, Y.; Coste, A.; Attree, I.; Frank, D. W.; Clevers, H.; Peters, P. J.; Cougoule, C.; Planes, R.; Meunier, E.
10.1101/2021.02.17.431580 — immunology — Posted on 2021-02-17
1671 Systemic administration of Ivabradine, an HCN channel inhibitor, blocks spontaneous absence seizures
Iacone, Y.; Morais, T. P.; David, F.; Delicata, F.; Sandle, J.; Raffai, T.; Parri, R.; Weisser, J. J.; Bundgaard, C.; Klewe, I. V.; Tamas, G.; Thomsen, M. S.; Crunelli, V.; Lorincz, M. L.
10.1101/2021.02.17.431588 — neuroscience — Posted on 2021-02-17
1677 Defining the Yeast Resistome through in vitro Evolution and Whole Genome Sequencing
Ottilie, S.; Luth, M. R.; Hellemann, E.; Goldgof, G. M.; Vigil, E.; Kumar, P.; Cheung, A. L.; Song, M.; Godinez-Macias, K. P.; Carolino, K.; Yang, J.; Lopez, G.; Abraham, M.; Tarsio, M.; LeBlanc, E.; Whitesell, L.; Schenken, J.; Gunawan, F.; Patel, R.; Smith, J.; Love, M. S.; Williams, R. M.; McNamara, C. W.; Gerwick, W. H.; Ideker, T.; Suzuki, Y.; Wirth, D. F.; Lukens, A. K.; Kane, P. M.; Cowen, L. E.; Durrant, J. D.; Winzeler, E. A.
10.1101/2021.02.17.430112 — genetics — Posted on 2021-02-17
1678 A tissue-aware machine learning framework enhances the mechanistic understanding and genetic diagnosis of Mendelian and rare diseases
Simonovsky, E.; Sharon, M.; Ziv, M.; Mauer, O.; Hekselman, I.; Jubran, J.; Vinogradov, E.; Argov, C. M.; Basha, O.; Kerber, L.; Yogev, Y.; Segre, A.; Im, H. K.; GTEx Consortium, ; Birk, O.; Rokach, L.; Yeger-Lotem, E.
10.1101/2021.02.16.430825 — genetics — Posted on 2021-02-17
1681 Multidimensional Single-Nuclei RNA-Seq Reconstruction of Adipose Tissue Reveals Adipocyte Plasticity Underlying Thermogenic Response
Biagi, C. A.; Cury, S. S.; Alves, C. P.; Rahbi, N.; Silva, W. A.; Farmer, S. R.; Carvalho, R. F.; Batista, M. L.
10.1101/2021.02.16.431320 — cell biology — Posted on 2021-02-17
1682 Host preferences of coexisting Perkinsea parasitoids during coastal dinoflagellate blooms
Rene, A.; Timoneda, N.; Sampedro, N.; Alacid, E.; Gallisai, R.; Gordi, J.; Fernandez-Valero, A. D.; Pernice, M. C.; Flo, E.; Garces, E.
10.1101/2021.02.17.431570 — molecular biology — Posted on 2021-02-17
1683 F-type Pyocins are Diverse Non-Contractile Phage Tail-Like Weapons for Killing Pseudomonas aeruginosa
Saha, S.; Ojobor, C.; MacKinnon, E.; North, O. I.; Bondy-Denomy, J.; Lam, J. S.; Ensminger, A.; Maxwell, K. L.; Davidson, A. R.
10.1101/2021.02.16.431561 — microbiology — Posted on 2021-02-17
1684 Similar neural and perceptual masking effects of low-power optogenetic stimulation in primate V1
Chen, S. C.-Y.; Benvenuti, G.; Chen, Y.; Kumar, S.; Ramakrishnan, C.; Deisseroth, K.; Geisler, W. S.; Seidemann, E.
10.1101/2021.02.16.431182 — neuroscience — Posted on 2021-02-17
1686 Dynamic Auditory Remapping Across the Sleep-Wake Cycle
Arzi, A.; Trentin, C.; Laudini, A.; Krugliak, A.; Nikolla, D.; Bekinschtein, T.
10.1101/2021.02.16.431383 — neuroscience — Posted on 2021-02-17
1688 Structural basis for the Pr-Pfr long-range signaling mechanism of a full-length bacterial phytochrome at the atomic level
Otero, L. H.; Foscaldi, S.; Antelo, G. T.; Sirigu, S.; Klinke, S.; Defelipe, L. A.; Sanchez-Lamas, M.; Battocchio, G.; Chavas, L. M. G.; Goldbaum, F. A.; Mroginski, M. A.; Rinaldi, J.; Bonomi, H. R.
10.1101/2021.02.16.430237 — biophysics — Posted on 2021-02-17
1689 Mapping densely distributed membrane receptors in blood platelets with expansion microscopy
Heil, H. S.; Aigner, M.; Maier, S.; Goeb, V.; Kusch, C.; Meub, M.; Nieswandt, B.; Stegner, D.; Heinze, K. G.
10.1101/2021.02.16.431449 — biophysics — Posted on 2021-02-17
1691 Robust clustering and interpretation ofscRNA-seq data using reference componentanalysis
Schmidt, F.; Ranjan, B.; Xiao Xuan Lin, Q.; Krishnan, V.; Joanito, I.; Honardoost, M. A.; Nawaz, Z.; Venkatesh, P. N.; Tan, J.; Rayan, N. A.; Ong, S. T.; Prabhakar, S.
10.1101/2021.02.16.431527 — bioinformatics — Posted on 2021-02-17
1692 Synthesizing VERDICT maps from standard diffusion mp-MRI data using GANs
Chiou, E.; Valindria, V.; Giganti, F.; Punwani, S.; Kokkinos, I.; Panagiotaki, E.
10.1101/2021.02.16.431521 — bioengineering — Posted on 2021-02-17
1693 Polymorphism of Genetic Ambigrams
Dudas, G.; Huber, G.; Wilkinson, M.; Yllanes, D.
10.1101/2021.02.16.431493 — genomics — Posted on 2021-02-17
1694 Gene loss during the transition to multicellularity
Jimenez-Marin, B.; Rakijas, J. B.; Tyagi, A.; Pandey, A.; Hanschen, E. R.; Anderson, J.; Heffel, M. G.; Platt, T. G.; Olson, B. J. S. C.
10.1101/2021.02.16.431445 — evolutionary biology — Posted on 2021-02-17
1697 Simons Collaborative Marine Atlas Project (Simons CMAP): an open-source portal to share, visualize and analyze ocean data
Dehghani Ashkezari, M.; Hagen, N. R.; Denholtz, M.; Neang, A.; Burns, T. C.; Morales, R. L.; Lee, C.; Hill, C.; Armbrust, E. V.
10.1101/2021.02.16.431537 — ecology — Posted on 2021-02-17
1698 Hierarchical reactivation of transcription during mitosis-to-G1 transition by Brn2 and Ascl1 in neural stem cells
Soares, M. A. F.; Soares, D. S.; Teixeira, V.; Bressan, R. B.; Pollard, S. M.; Oliveira, R. A.; Castro, D. S.
10.1101/2021.02.17.431407 — developmental biology — Posted on 2021-02-17
1700 Biomolecular recognition of the glycan neoantigen CA19-9 by distinct antibodies
Borenstein-Katz, A.; Warszawski, S.; Amon, R.; Tasnima, N.; Yu, H.; Chen, X.; Padler-Karavani, V.; Fleishman, S. J.; Diskin, R.
10.1101/2021.02.17.431565 — molecular biology — Posted on 2021-02-17
1702 Molecular effects of mannanase-hydrolyzed coprameal to intestinal immunity in the Pacific white shrimp (Litopenaeus vannamei )
Rungrassamee, W.; Arayamethakorn, S.; Karoonuthaisiri, N.; Chen, S.-C.; Chang, E.; Chan, S.; Yoshida, Y.; Maebuchi, M.; Ibuki, M.
10.1101/2021.02.16.431529 — molecular biology — Posted on 2021-02-17
1703 Psilocin acutely disrupts sleep and affects local but not global sleep homeostasis in laboratory mice
Thomas, C. W.; Blanco-Duque, C.; Breant, B.; Sharp, T.; Goodwin, G.; Bannerman, D.; Vyazovskiy, V. V.
10.1101/2021.02.16.431276 — neuroscience — Posted on 2021-02-17
1706 CAN CARBON NANOFIBERS AFFECT ANUROFAUNA? STUDY INVOLVING NEOTROPICAL Physalaemus cuvieri (Fitzinger, 1826) TADPOLES
Guimaraes, A. T. B.; Estrela, F. N.; Rodrigues, A. S. d. L.; Nobrega, R. H.; Charlie-Silva, I.; Malafaia, G.
10.1101/2021.02.16.431548 — zoology — Posted on 2021-02-17
1707 Early Dynamics of Chronic Myeloid Leukemia on Nilotinib Predicts Deep Molecular Response
Okamoto, Y.; Hirano, M.; Morino, K.; Kajita, M. K.; Nakaoka, S.; Tsuda, M.; Sugimoto, K.-j.; Tamaki, S.; Hisatake, J.; Yokoyama, H.; Igarashi, T.; Shinagawa, A.; Sugawara, T.; Hara, S.; Fujikawa, K.; Shimizu, S.; Yujiri, T.; Wakita, H.; Nishiwaki, K.; Tojo, A.; Aihara, K.
10.1101/2021.02.17.431221 — systems biology — Posted on 2021-02-17
1708 Leptin regulates glucose homeostasis via the canonical WNT pathway.
Kamstra, K.; Rizwan, M.; Horsfield, J. A.; Pretz, D.; Shepherd, P. R.; Grattan, D. R.; Tups, A.
10.1101/2021.02.16.431518 — physiology — Posted on 2021-02-17
1711 Nuclear HMGB1 protects from non-alcoholic fatty liver diseases through negative regulation of liver X receptor
Personnaz, J.; Piccolo, E.; Dortignac, A.; Iacovoni, J. S.; Mariette, J.; Polizzi, A.; Batut, A.; Deleruyelle, S.; Paccoud, R.; Moreau, E.; Martins, F.; Clouaire, T.; Benhamed, F.; Montagner, A.; Wahli, W. A.; Schwabe, R. F.; Yart, A.; Castan-Laurell, I.; Postic, C.; Moro, C.; Legube, G.; Lee, C.-H.; Guillou, H.; Valet, P.; Dray, C.; Pradere, J.-P.
10.1101/2021.02.17.431446 — pathology — Posted on 2021-02-17
1712 Spatiotemporal heterogeneity of glioblastoma is dictated by microenvironmental interference
Ravi, V. M.; Will, P.; Kuekelhaus, J.; Sun, N.; Joseph, K.; Salie, H.; von Ehr, J.; Vollmer, L.; Benotmane, J. K.; Neidert, N.; Follo, M.; Scherer, F.; Goeldner, J.; Behringer, S. P.; Franco, P.; Hofmann, U. G.; Fung, C.; Beck, J.; Sankowski, R.; Prinz, M.; Killmer, S.; Bengsch, B.; Walch, A. K.; Delev, D.; Schnell, O.; Heiland, D. H.
10.1101/2021.02.16.431475 — cancer biology — Posted on 2021-02-17
1714 A non-canonical role for glutamate decarboxylase 1 in cancer cell amino acid homeostasis, independent of the GABA shunt.
Samborska, B.; Griss, T.; Ma, E. H.; Jones, N.; Williams, K. S.; Sergushichev, A.; Johnson, R. M.; Esaulova, E.; Loginicheva, E.; Flynn, B.; Blagih, J.; Artyomov, M. N.; Jones, R. G.; Vincent, E. E.
10.1101/2021.02.17.431489 — cancer biology — Posted on 2021-02-17
1717 AirLift: A Fast and Comprehensive Technique for Remapping Alignments between Reference Genomes
Kim, J. S.; Firtina, C.; Cavlak, M. B.; Cali, D. S.; Hajinazar, N.; Alser, M.; Alkan, C.; Mutlu, O.
10.1101/2021.02.16.431517 — bioinformatics — Posted on 2021-02-17
1718 PhylEx: Accurate reconstruction of clonal structure via integrated analysis of bulk DNA-seq and single cell RNA-seq data
Jun, S.-H.; Toosi, H.; Mold, J.; Engblom, C.; Chen, X.; O'Flanagan, C.; Hagemann-Jensen, M.; Sandberg, R.; Aparicio, S.; Hartman, J.; Roth, A.; Lagergren, J.
10.1101/2021.02.16.431009 — bioinformatics — Posted on 2021-02-17
1722 Ancient migrations - The first complete genome assembly, annotation and variants of the Zoroastrian-Parsi community of India
Pasha, N.; Krishnasamy, K.; Nagarajan, N.; Mutya, S.; Mam, B.; Sonnekhan, K.; Gopalakrishnan, C.; Jain, R.; Patell, V.-M.
10.1101/2021.02.17.431362 — genomics — Posted on 2021-02-17
1723 Social stratification without genetic differentiation at the site of Kulubnarti in Christian Period Nubia
Sirak, K. A.; Fernandes, D. M.; Lipson, M.; Mallick, S.; Mah, M.; Olalde, I.; Ringbauer, H.; Rohland, N.; Hadden, C. S.; Harney, E.; Adamski, N.; Bernardos, R.; Broomandkhoshbacht, N.; Callan, K.; Ferry, M.; Lawson, A. M.; Michel, M.; Oppenheimer, J.; Stewardson, K.; Zalzala, F.; Patterson, N.; Pinhasi, R.; Thompson, J. C.; Van Gerven, D. P.; Reich, D.
10.1101/2021.02.17.431423 — genomics — Posted on 2021-02-17
1725 The expression of deep-sea fish visual genes supports a conserved cone-to-rod vertebrate retinal development
Lupse, N.; Cortesi, F.; Freese, M.; Marohn, L.; Pohlman, J.-D.; Wysujack, K.; Hanel, R.; Musilova, Z.
10.1101/2020.05.25.114991 — evolutionary biology — Posted on 2021-02-17
1726 Role and patterns of butterflies and hawkmoths in plant-pollinator networks at different elevations and seasons in tropical rainforests of Mount Cameroon
Mertens, J. E. J.; Brisson, L.; Janecek, S.; Klomberg, Y.; Maicher, V.; Safian, S.; Delabye, S.; Potocky, P.; Kobe, I. N.; Pyrcz, T.; Tropek, R.
10.1101/2021.02.16.431477 — ecology — Posted on 2021-02-17
1728 Integrating plant stoichiometry and feeding experiments: state-dependent forage choice and its implications on body mass
Balluffi-Fry, J.; Leroux, S.; Wiersma, Y. F.; Richmond, I.; Heckford, T.; Rizzuto, M.; Kennah, J.; Vander Wal, E.
10.1101/2021.02.16.431523 — ecology — Posted on 2021-02-17
1729 A visual tour of carbon export by sinking particles
Durkin, C. A.; Buesseler, K. O.; Cetinic, I.; Estapa, M. L.; Kelly, R. P.; Omand, M.
10.1101/2021.02.16.431317 — ecology — Posted on 2021-02-17
1731 Cardiac Specific Overexpression of Transcription Factor EB (TFEB) in Normal Hearts Induces Pathologic Cardiac Hypertrophy and Lethal Cardiomyopathy
Kenny, H. C.; Weatherford, E. T.; Collins, G. V.; Allamargot, C.; Gesalla, T.; Zimmerman, K.; Goel, H.; McLendon, J. M.; Dai, D.-F.; Romac, T.; Streeter, J.; Abhinav, D.; Pereira, R. O.; Sharafuddin, J.; Song, L.-S.; Abel, E. D.
10.1101/2021.02.16.431474 — cell biology — Posted on 2021-02-17
1733 A parasite's paradise: Biotrophic species prevail oomycete community composition in tree canopies
Jauss, R.-T.; Walden, S.; Fiore-Donno, A. M.; Schaffer, S.; Wolf, R.; Feng, K.; Bonkowski, M.; Schlegel, M.
10.1101/2021.02.17.431613 — microbiology — Posted on 2021-02-17
1734 Viral and parasitic cell ratios per free-living microbe across ecosystems
Lopez-Garcia, P.; Gutierrez-Preciado, A.; Ciobanu, M.; Deschamps, P.; Jardillier, L.; Lopez-Perez, M.; Rodriguez-Valera, F.; Moreira, D.
10.1101/2021.02.17.431581 — microbiology — Posted on 2021-02-17
1736 Traces of transposable element in genome dark matter co-opted by flowering gene regulation networks.
Baud, A.; Wan, M.; Nouaud, D.; Francillonne, N.; Anxolabehere, D.; Quesneville, H.
10.1101/547877 — genomics — Posted on 2021-02-17
1737 Anatomy, transcription dynamics and evolution of wheat ribosomal RNA loci deciphered by a multi-omics approach
Tulpova, Z.; Kovarik, A.; Toegelova, H.; Navratilova, P.; Kapustova, V.; Hribova, E.; Vrana, J.; Macas, J.; Dolezel, J.; Simkova, H.
10.1101/2020.08.29.273623 — genomics — Posted on 2021-02-17
1738 A suite of rare microbes interacts with a dominant, heritable, fungal endophyte to influence plant trait expression
Harrison, J.; Beltran, L. P.; Buerkle, C. A.; Cook, D.; Gardner, D.; Parchman, T. L.; Poulson, S. R.; Forister, M. L.
10.1101/608729 — ecology — Posted on 2021-02-17
1739 Measurement of Klebsiella Intestinal Colonization Density to Assess Infection Risk
Sun, Y.; Patel, A.; SantaLucia, J.; Roberts, E.; Zhao, L.; Kaye, K. S.; Rao, K.; Bachman, M. A.
10.1101/2021.02.16.431551 — microbiology — Posted on 2021-02-17
1741 A selective sweep in the Spike gene has driven SARS-CoV-2 human adaptation
Kang, L.; He, G.; Sharp, A. K.; Wang, X.; Brown, A. M.; Michalak, P.; Weger-Lucarelli, J.
10.1101/2021.02.13.431090 — microbiology — Posted on 2021-02-17
1742 A measles-vectored COVID-19 vaccine induces long-term immunity and protection from SARS-CoV-2 challenge in mice
Frantz, P. N.; Barinov, A.; Ruffie, C.; Combredet, C.; Najburg, V.; Teeravechyan, S.; Jongkaewwattana, A.; Prot, M.; Conquet, L.; Montagutelli, X.; Fernandes, P.; Strick-Marchand, H.; Di Santo, J.; Simon-Loriere, E.; Gerke, C.; Tangy, F.
10.1101/2021.02.17.431630 — immunology — Posted on 2021-02-17
1744 Crowdsourced Identification of Multi-Target Kinase Inhibitors for RET- and TAU- Based Disease: the Multi-Targeting Drug DREAM Challenge
Xiong, Z.; Jeon, M.; Allaway, R. J.; Kang, J.; Park, D.; Lee, J.; Jeon, H.; Ko, M.; Jiang, H.; Zheng, M.; Tan, A. C.; Guo, X.; The Multi-Targeting Drug DREAM Challenge Community, ; Dang, K. K.; Tropsha, A.; Hecht, C.; Das, T. K.; Carlson, H. A.; Abagyan, R.; Guinney, J.; Schlessinger, A.; Cagan, R.
10.1101/2021.02.15.430538 — pharmacology and toxicology — Posted on 2021-02-17
1745 HLA binding of self-peptides is biased towards proteins with specific molecular functions
Karnaukhov, V.; Paes, W.; Woodhouse, I. B.; Partridge, T.; Nicastri, A.; Brackenridge, S.; Scherbinin, D.; Chudakov, D. M.; Zvyagin, I.; Ternette, N.; Koohy, H.; Borrow, P.; Shugay, M.
10.1101/2021.02.16.431395 — bioinformatics — Posted on 2021-02-17
1750 Col6a1+/CD201+ telocytes regulate intestinal morphogenesis and homeostasis
Melissari, M.-T.; Henriques, A.; Tzaferis, C.; Prados, A.; Sarris, M. E.; Chouvardas, P.; Grammenoudi, S.; Kollias, G.; Koliaraki, V.
10.1101/2021.02.16.431453 — cell biology — Posted on 2021-02-17
1751 Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization
Turner, H. L.; Andrabi, R.; Cottrell, C. A.; Richey, S. T.; Song, G.; Callaghan, S.; Anzanello, F.; Moyer, T. J.; Abraham, W.; Melo, M.; Silva, M.; Scaringi, N.; Rakasz, E. G.; Sattentau, Q. J.; Irvine, D. J.; Burton, D. R.; Ward, A. B.
10.1101/2021.02.16.431310 — immunology — Posted on 2021-02-17
1756 Neurovascular unit alterations in the growth restricted newborn are improved following ibuprofen treatment
Chand, K. K.; Miller, S. M.; Cowin, G. J.; Mohanty, L.; Pienaar, J.; Colditz, P. B.; Bjorkman, S. T.; Wixey, J. A.
10.1101/2021.02.15.431329 — neuroscience — Posted on 2021-02-17
1758 Accessibility Over Transposable Elements Reveals Genetic Determinants of Stemness Properties in Normal and Leukemic Hematopoiesis
Nadorp, B.; Grillo, G.; Qamra, A.; Mitchell, A.; Arlidge, C.; Takayama, N.; Murison, A.; Tonekaboni, S. A. M.; Arruda, A.; Wang, J.; Minden, M.; Dick, J.; Lupien, M.
10.1101/2021.02.16.431334 — cancer biology — Posted on 2021-02-17
1759 Computational Fluid Dynamics Modeling of Cough Transport in an Aircraft Cabin
Davis, A. C.; Zee, M.; Clark, A. D.; Wu, T.; Jones, S. P.; Waite, L. L.; Cummins, J. J.; Olson, N. A.
10.1101/2021.02.15.431324 — biophysics — Posted on 2021-02-17
1766 The winding roads to adulthood: a twin study
Rimfeld, K.; Malanchini, M.; Packer, A. E.; Gidziela, A.; Allegrini, A. G.; Ayorech, Z.; Smith-Woolley, E.; McMillan, A.; Ogden, R.; Dale, P. S.; Eley, T. C.; Plomin, R.
10.1101/2021.02.16.431456 — genetics — Posted on 2021-02-17
1769 Sexual Conflict Over Survival In Trinidadian Guppies
Lin, Y.; Darolti, I.; Furman, B. L. S.; Almeida, P.; Sandkam, B. A.; Breden, F.; Wright, A. E.; Mank, J. E.
10.1101/2021.02.16.431319 — evolutionary biology — Posted on 2021-02-17
1771 Delta C2 Domain β1-2 loop contributes to robust Notch signalling
Martins, T.; Meng, Y.; Korona, B.; Suckling, R.; Johnson, S.; Handford, P.; Lea, S. M.; Bray, S. J.
10.1101/2021.02.16.431397 — developmental biology — Posted on 2021-02-17
1772 In-cell structures of a conserved supramolecular array at the mitochondria-cytoskeleton interface in mammalian sperm
Leung, M. R.; Zenezini Chiozzi, R.; Roelofs, M.; Hevler, J. F.; Ravi, R. T.; Maitan, P.; Henning, H.; Zhang, M.; Bromfield, E.; Howes, S.; Gadella, B.; Heck, A. J. R.; Zeev-Ben-Mordehai, T.
10.1101/2021.02.16.431372 — cell biology — Posted on 2021-02-17
1775 FIBRIN POLYMER ON THE SURFACE OF BIOMATERIAL IMPLANTS DRIVES THE FOREIGN BODY REACTION
Balabiyev, A.; Podolnikova, N. P.; Kilbourne, J. A.; Baluch, D. P.; Lowry, D.; Zare, A.; Ros, R.; Flick, M. J.; Ugarova, T. P.
10.1101/2021.02.16.431282 — immunology — Posted on 2021-02-17
1776 Human primed endothelial colony forming cells exert neuroprotective effects in the growth restricted newborn piglet
Chand, K. K.; Patel, J.; Bjorkman, S. T.; Sim, S. L.; Miller, S. M.; Teo, E.; Jones, L.; Sun, J.; Colditz, P. B.; Khosrotehrani, K.; Wixey, J. A.
10.1101/2021.02.15.431307 — neuroscience — Posted on 2021-02-17
1778 Ketamine disrupts gaze patterns during face viewing in the common marmoset
Schaeffer, D. J.; Selvanayagam, J.; Wong, R. K.; Johnston, K.; Everling, S.
10.1101/2021.02.16.431438 — neuroscience — Posted on 2021-02-17
1783 Plant trait heterosis is quantitatively associated with expression heterosis of plastid ribosomal proteins
Birdseye, D.; De Boer, L.; Shen, Z.; Bai, H.; Zhou, P.; Schmelz, E. A.; Springer, N. M.; Briggs, S.
10.1101/2021.02.16.431485 — plant biology — Posted on 2021-02-17
1784 AGL16 negatively modulates stress response to balance with growth
Xiang, C.; Zhao, P.-X.; Zhang, J.; Chen, S.-Y.; Wu, J.; Xia, J.-Q.; Sun, L.-Q.; Ma, S.
10.1101/2021.02.16.431464 — plant biology — Posted on 2021-02-17
1785 A systems-level analysis of dynamic total-body PET data reveals complex skeletal energy metabolism networks in vivo
Suchacki, K. J.; Alcaide-Corral, C. J.; Nimale, S.; Macaskill, M. G.; Stimson, R. H.; Farquharson, C.; Freeman, T. C.; Tavares, A. A. S.
10.1101/2021.02.16.431368 — physiology — Posted on 2021-02-17
1793 MultiMAP: Dimensionality Reduction and Integration of Multimodal Data
Jain, M. S.; Dominguez Conde, C.; Polanski, K.; Chen, X.; Park, J.; Botting, R.; Stephenson, E.; Haniffa, M.; Lamacraft, A.; Efremova, M.; Teichmann, S.
10.1101/2021.02.16.431421 — bioinformatics — Posted on 2021-02-17
1798 Understanding distribution and occupancy of Himalayan Monal in Uttarkashi district, Uttarakhand
Sharief, A.; Singh, H.; Joshi, B. D.; Mukherjee, T.; Chandra, K.; Thakur, M.; Sharma, L. K.
10.1101/2021.02.16.431367 — ecology — Posted on 2021-02-17
1800 Osmolarity-regulated swelling initiates egg activation in Drosophila
York-Andersen, A. H.; Wood, B. W.; Wilby, E. L.; Berry, A. S.; Weil, T. T.
10.1101/2021.02.16.431163 — developmental biology — Posted on 2021-02-17
1802 Cerebellar tDCS alters the perception of optic flow
Nankoo, J.-F.; Madan, C. R.; Medina, O.; Makepeace, T.; Striemer, C. L.
10.1101/2021.02.15.431326 — neuroscience — Posted on 2021-02-17
1810 An HB40 - JUNGBRUNNEN1 - GA 2-OXIDASE regulatory module for gibberellin homeostasis in Arabidopsis
Dong, S.; Tarkowska, D.; Sedaghatmehr, M.; Molochko, M.; Gupta, S.; Mueller-Roeber, B.; Balazadeh, S.
10.1101/2021.02.17.431590 — plant biology — Posted on 2021-02-17
1811 Reexamination of N-terminal domains of Syntaxin-1 in vesicle fusion from central murine synapses
Vardar, G.; Salazar-Lazaro, A.; Brockmann, M.; Weber-Boyvat, M.; Zobel, S.; Kumbol, V. W.-A.; Trimbuch, T.; Rosenmund, C.
10.1101/2021.02.15.431257 — neuroscience — Posted on 2021-02-17
1812 Inferring population histories for ancient genomes using genome-wide genealogies
Speidel, L.; Cassidy, L.; Davies, R. W.; Hellenthal, G.; Skoglund, P.; Myers, S.
10.1101/2021.02.17.431573 — genomics — Posted on 2021-02-17
1813 A unified genealogy of modern and ancient genomes
Wohns, A. W.; Wong, Y.; Jeffery, B.; Akbari, A.; Mallick, S.; Pinhasi, R.; Patterson, N.; Reich, D.; Kelleher, J.; McVean, G.
10.1101/2021.02.16.431497 — genomics — Posted on 2021-02-17
1815 Deep behavioral phenotyping of mouse autism models using open-field behavior
Klibaite, U.; Kislin, M.; Verpeut, J. L.; Sun, X.; Shaevitz, J. W.; Wang, S. S.- H.
10.1101/2021.02.16.431500 — neuroscience — Posted on 2021-02-17
1818 Cholecystokinin 1 Receptor (Cck1R) Activates mTORC1 signaling and is Protective to Purkinje cells in SCA Mice
Wozniak, E. A. L.; Chen, Z.; Yang, P.; Tschumperlin, T.; Berken, M.; Ingram, M.; Henzler, C.; Orr, H. T.
10.1101/2021.02.16.431490 — neuroscience — Posted on 2021-02-17
1819 Laminar dynamics of beta bursts in human motor cortex
Bonaiuto, J. J.; Little, S.; Neymotin, S. A.; Jones, S. R.; Barnes, G. R.; Bestmann, S.
10.1101/2021.02.16.431412 — neuroscience — Posted on 2021-02-17
1821 NECAB2 orchestrates an endosomal pathway of mitochondrial quality control at striatal synapses
Narayan Dey, P.; Bueno, D.; Schacht, T.; Wolf, C.; Wüllner, V.; Morpurgo, E.; Rojas-Charry, L.; Sessinghaus, L.; Leukel, P.; Sommer, C.; Radyushkin, K.; Schaefer, M.; Florin, L.; Tenzer, S.; Baumgart, J.; Stamm, P.; Daiber, A.; Horta, G.; Nardi, L.; Vasic, V.; Schmeisser, M. J.; Hellwig, A.; Oskamp, A.; Bauer, A.; Anand, R.; Reichert, A. S.; Ritz, S.; Silies, M.; Frauenknecht, K. B. M.; Methner, A.
10.1101/2021.02.15.431234 — neuroscience — Posted on 2021-02-17
1824 Cardiac Specific Overexpression of Transcription Factor EB (TFEB) in Normal Hearts Induces Pathologic Cardiac Hypertrophy and Lethal Cardiomyopathy
Kenny, H. C.; Weatherford, E. T.; Collins, G. V.; Allamargot, C.; Gesalla, T.; Zimmerman, K.; Goel, H.; McLendon, J. M.; Dai, D.-F.; Romac, T.; Streeter, J.; Abhinav, D.; Pereira, R. O.; Sharafuddin, J.; Song, L.-S.; Abel, E. D. C.
10.1101/2021.02.16.431474 — cell biology — Posted on 2021-02-17
1825 Metagenomes from the Loxahatchee wildlife refuge in the Florida Everglades
Benskin, J. B.; Alvarez, D. A.; Cadavid, N. A.; Childs, C. A.; Cupelli, M. F.; De, L. A.; Diaz, A. M.; Eldridge, S. A.; Elhabashy, Y. B.; Fleming, A. E.; Fox, N. A.; Franco, M.; Gaspari, J. C.; Gerstin, I. M.; Gibson, K. A.; Huott, A. L.; Johnson, A. O.; Majhess, E. G.; Mantilla, G.; Perez, G. S.; Prieto, J. J.; Reutter, B. C.; Rivera, E. I.; Rootes, T. R.; Sellers, J.; Streibig, A. M.; Wilkinson, J. S.; Zayas-Bazan, S.; Bhadha, J. H.; Clum, A.; Daum, C.; Glavina del Rio, T.; Lail, K.; Roux, S.; Eloe-Fadrosh, E.
10.1101/2021.02.16.430518 — microbiology — Posted on 2021-02-17
1826 Three-dimensional interactions between integrated HPV genomes and cellular chromatin dysregulate host gene expression in early cervical carcinogenesis
Groves, I. J.; Drane, E. L.; Michalski, M.; Monahan, J. M.; Scarpini, C. G.; Smith, S. P.; Bussotti, G.; Varnai, C.; Schoenfelder, S.; Fraser, P.; Enright, A. J.; Coleman, N.
10.1101/2021.02.03.429496 — cancer biology — Posted on 2021-02-17
1827 A rank-normalized archaeal taxonomy based on genome phylogeny resolves widespread incomplete and uneven classifications
Rinke, C.; Chuvochina, M.; Mussig, A. J.; Chaumeil, P.-A.; Waite, D. W.; Whitman, W. B.; Parks, D. H.; Hugenholtz, P.
10.1101/2020.03.01.972265 — microbiology — Posted on 2021-02-17
1834 VAMPIRE: A model blood cell trait focused annotation tool for interpretation and prioritization of complex trait genome-wide association study results
Crowley, C. A.; Sun, Q.; Huang, L.; Bao, E. L.; Auer, P.; Lettre, G.; Reiner, A. P.; Sankaran, V. G.; Raffield, L. M.; Li, Y.
10.1101/2021.02.16.431409 — genetics — Posted on 2021-02-16
1839 A mixture of generative models strategy helps humans generalize across tasks
HERCE CASTANON, S.; Cardoso-Leite, P.; Green, C. S.; Altarelli, I.; Schrater, P.; Bavelier, D.
10.1101/2021.02.16.431506 — neuroscience — Posted on 2021-02-16
1840 Shared long-term and short-term memory representational formats in occipital and parietal cortex
Vo, V. A.; Sutterer, D. W.; Foster, J. J.; Sprague, T. C.; Awh, E.; Serences, J. T.
10.1101/2021.02.16.431528 — neuroscience — Posted on 2021-02-16
1845 Endothelial cells elicit a pro-inflammatory response to SARS-COV-2 without productive viral infection
Schimmel, L.; Chew, K. Y.; Stocks, C.; Yordanov, T.; Essebier, T.; Kulasinghe, A.; Monkman, J.; Miggiolaro, A. F. R. d. S.; De Noronha, L.; Lagendijk, A. K.; Schroder, K.; Labzin, L.; Gordon, E. J.; Short, K. R.
10.1101/2021.02.14.431177 — cell biology — Posted on 2021-02-16
1850 Functional basis for calmodulation of the TRPV5 calcium channel
Roig, S. R.; Thijssen, N.; van Erp, M.; Fransen, J.; Hoenderop, J.; van der Wijst, J.
10.1101/2021.02.16.431366 — cell biology — Posted on 2021-02-16
1852 Diversity of excitatory release sites
Karlocai, R. R.; Heredi, J.; Benedek, T.; Holderith, N.; Lorincz, A.; Nusser, Z.
10.1101/2021.02.15.431316 — neuroscience — Posted on 2021-02-16
1855 A practical modification to a resting state fMRI protocol for improved characterization of cerebrovascular function
Stickland, R. C.; Zvolanek, K. M.; Moia, S. C.; Ayyagari, A.; Caballero-Gaudes, C.; Bright, M. G.
10.1101/2021.02.15.431289 — neuroscience — Posted on 2021-02-16
1856 N-Terminal finger stabilizes the reversible feline drug GC376 in SARS-CoV-2 Mpro
Arutyunova, E.; Khan, M. B.; Fischer, C.; Lu, J.; Lamer, T.; Vuong, W.; van Belkum, M. J.; McKay, R. T.; Tyrrell, D. L.; Vederas, J. C.; Young, H. S.; Lemieux, M. J.
10.1101/2021.02.16.431021 — biophysics — Posted on 2021-02-16
1857 The Host Interactome of Spike Expands the Tropism of SARS-CoV-2
Bamberger, T. C.; Pankow, S.; Martinez-Bartolome, S.; Diedrich, J.; Park, R.; Yates, J. R.
10.1101/2021.02.16.431318 — molecular biology — Posted on 2021-02-16
1858 Synchrony between daily rhythms of malaria parasites and hosts is driven by an essential amino acid
Prior, K. F.; Middleton, B.; Owolabi, A. T.; Westwood, M. L.; Holland, J.; O'Donnell, A. J.; Blackman, M. J.; Skene, D. J.; Reece, S. E.
10.1101/2020.08.24.264689 — microbiology — Posted on 2021-02-16
1860 Single-Domain SARS-CoV-2 S1 and RBD Antibodies Isolated from Immunized Llama Effectively Bind Targets of the Wuhan, UK, and South African Strains in vitro
Yamane, D.; Lu, I.; Tiahjono, W.; Rubidoux, L.; Hussain, A.; Cancilla, J. C.; Duggan, E.; Shaner, N. C.; Nakanishi, N.; Wang, J.
10.1101/2021.02.15.431198 — immunology — Posted on 2021-02-16
1861 Hepatitis C Virus E1 Protein Enhances Macrophage iNOS Expression In Vitro
Munkhjargal, B.; Enkhtuvshin, B.; Ulziisaikhan, U.; Tuvdenjamts, B.; Unurbuyan, K.; Sandagdorj, D.; Enkhjargal, B.; Sandag, T.; Tsolmon, B.; Lkhagvasuren, E.
10.1101/2021.02.15.431273 — immunology — Posted on 2021-02-16
1867 Differential contributions of M1 and pre-M1 to ion selectivity in ASICs and ENaCs
Sheikh, Z. P.; Wulf, M.; Friis, S.; Althaus, M.; Lynagh, T.; Pless, S. A.
10.1101/2021.02.16.431267 — biophysics — Posted on 2021-02-16
1869 Quality control and processing of nascent RNA profiling data
Smith, J. P.; Dutta, A. B.; Sathyan, K. M.; Guertin, M. J.; Sheffield, N. C.
10.1101/2020.02.27.956110 — bioinformatics — Posted on 2021-02-16
1871 A new method for determining ribosomal DNA copy number shows differences between Saccharomyces cerevisiae populations
Sharma, D.; Hermann-Le Denmat, S.; Matzke, N. J.; Hannan, K.; Hannan, R. D.; O'Sullivan, J. M.; Ganley, A. R. D.
10.1101/2021.01.21.427686 — genomics — Posted on 2021-02-16
1873 Validating a high-throughput tracking system: ATLAS as a regional-scale alternative to GPS
Beardsworth, C. E.; Gobbens, E.; van Maarseveen, F.; Denissen, B.; Dekinga, A.; Nathan, R.; Toledo, S.; Bijleveld, A. I.
10.1101/2021.02.09.430514 — ecology — Posted on 2021-02-16
1877 Do size and shape matter? Exploring the interactions and the metabolome of the soil isolate Hylemonella gracilis
Tyc, O.; Kulkarni, P.; Ossowicki, A.; Tracanna, V.; Medema, M.; Baarlen, P. v.; van IJcken, W.; Verhoeven, K. J. F.; Garbeva, P.
10.1101/2021.02.11.430889 — microbiology — Posted on 2021-02-16
1878 Nanoscale resolution of microbial fiber degradation in action
Tatli, M.; Morais, S.; Tovar-Herrera, O. E.; Bomble, Y.; Bayer, E. A.; Medalia, O.; Mizrahi, I.
10.1101/2021.02.16.431430 — microbiology — Posted on 2021-02-16
1879 Pilot study: Trehalose-induced remodelling of the human microbiota affects Clostridioides difficile infection outcome in an in vitro colonic model
Buckley, A.; Moura, I.; Arai, N.; Spittal, W.; Clark, E.; Nishida, Y.; Harris, H.; Bentley, K.; DAVIS, G.; Wang, D.; Mitra, S.; Higashiyama, T.; Wilcox, M. H.
10.1101/2021.02.16.431513 — microbiology — Posted on 2021-02-16
1880 Characterization of heliorhodopsins detected via functional metagenomics in freshwater Actinobacteria, Chloroflexi and Archaea
Chazan, A.; Rozenberg, A.; Mannen, K.; Nagata, T.; Tahan, R.; Yaish, S.; Larom, S.; Inoue, K.; Beja, O.; Pushkarev, A.
10.1101/2021.02.16.431466 — microbiology — Posted on 2021-02-16
1881 Development of chemosynthetic microbial communities in organic falls deployed in the deep Southwest Atlantic Ocean
Amendola, A. M.; Peres, F. V.; Moreira, J. C. F.; Sumida, P. Y. G.; Paula, F. S.; Pellizari, V. H.
10.1101/2021.02.16.431415 — microbiology — Posted on 2021-02-16
1882 Dynamin is primed at endocytic sites for ultrafast endocytosis
Imoto, Y.; Raychaudhuri, S.; Fenske, P.; Sandoval, E.; Itoh, K.; Blumrich, E.-M.; Mamer, L.; Zarebidaki, F.; Sohl-Kielczynski, B.; Trimbuch, T.; Nayak, S.; Iwasa, J. H.; Jorgensen, E. M.; Cousin, M. A.; Rosenmund, C. A.; Watanabe, S.
10.1101/2021.02.15.431332 — neuroscience — Posted on 2021-02-16
1883 Dietary folic acid deficiency impacts hippocampal morphology and cortical acetylcholine metabolism in adult male and female mice
Bennett, C.; Green, J.; Ciancio, M.; Goral, J.; Pitstick, L.; Pytynia, M.; Meyer, A.; Kwatra, N.; Jadavji, N. M.
10.1101/2020.12.13.422535 — neuroscience — Posted on 2021-02-16
1884 Single-cell analysis of the ventricular-subventricular zone reveals signatures of dorsal and ventral adult neurogenic lineages
Redmond, S. A.; Cebrian Silla, A.; Assis Nascimento, M.; Mansky, B.; Wu, D.; Obernier, K.; Romero Rodriguez, R.; Lim, D. A.; Alvarez-Buylla, A.
10.1101/2021.02.10.430525 — neuroscience — Posted on 2021-02-16
1885 Optical activation of TrkB neurotrophin receptor in mouse ventral hippocampus promotes plasticity and facilitates fear extinction
Umemori, J.; Didio, G.; Winkel, F.; Pou, M. L.; Harkki, J.; Lo Russo, G.; Verie, M.; Antila, H.; Buj, C.; Taira, T.; Sari, L.; Guirado, R.; Castren, E.
10.1101/2021.02.14.431126 — neuroscience — Posted on 2021-02-16
1887 A compressed representation of spatial distance in the rodent hippocampus
Sheehan, D. J.; Charczynski, S.; Fordyce, B. A.; Hasselmo, M. E.; Howard, M. W.
10.1101/2021.02.15.431306 — neuroscience — Posted on 2021-02-16
1891 Pharmacologic Therapy for Engraftment Arrhythmia Induced by Transplantation of Human Cardiomyocytes
Nakamura, K.; Neidig, L. E.; Yang, X.; Weber, G. J.; El-nachef, D.; Tsuchida, H.; Dupras, S.; Kalucki, F. A.; Jayabalu, A.; Futakuchi-Tsuchida, A.; Nakamura, D. S.; Marchiano, S.; Bertero, A.; Robinson, M. R.; Cain, K.; Whittington, D.; Reinecke, H.; Pabon, L.; Knollmann, B. C.; Kattman, S.; Thies, R. S.; MacLellan, W. R.; Murry, C. E.
10.1101/2021.02.15.431108 — pharmacology and toxicology — Posted on 2021-02-16
1892 The ratio of exhausted to resident infiltrating lymphocytes is prognostic for colorectal cancer patient outcome
Foroutan, M.; Molania, R.; Pfefferle, A.; Behrenbruch, C.; Kallies, A.; Speed, T. P.; Cursons, J.; Huntington, N. D.
10.1101/2020.12.19.423379 — cancer biology — Posted on 2021-02-16
1899 501Y.V2 and 501Y.V3 variants of SARS-CoV-2 lose binding to Bamlanivimab in vitro
Liu, H.; Wei, P.; Zhang, Q.; Chen, Z.; Aviszus, K.; Downing, W.; Peterson, S.; Reynoso, L.; Downey, G.; Frankel, S.; Kappler, J.; Marrack, P.; Zhang, G.
10.1101/2021.02.16.431305 — biochemistry — Posted on 2021-02-16
1900 Evaluation of Polygenic Prediction Methodology within a Reference-Standardized Framework
Pain, O.; Glanville, K. P.; Hagenaars, S. P.; Selzam, S. P.; Fürtjes, A. E.; Gaspar, H. A.; Coleman, J. R.; Rimfeld, K.; Breen, G.; Plomin, R.; Folkersen, L.; Lewis, C. M.
10.1101/2020.07.28.224782 — genomics — Posted on 2021-02-16
1902 Global detection of DNA repair outcomes induced by CRISPR-Cas9
Liu, M.; Zhang, W.; Xin, C.; Yin, J.; Shang, Y.; Ai, C.; Li, J.; Meng, F.-l.; Hu, J.
10.1101/2021.02.15.431335 — genomics — Posted on 2021-02-16
1903 Different evolutionary trends form the twilight zone of the bacterial pan-genome
Horesh, G.; Taylor-Brown, A.; McGimpsey, S.; Lassalle, F.; Corander, J.; Heinz, E.; Thomson, N. R.
10.1101/2021.02.15.431222 — genomics — Posted on 2021-02-16
1906 Bro1 stimulates Vps4 activity to promote Intralumenal Vesicle Formation during Multivesicular Body biogenesis
Tseng, C.-c.; Dean, S.; Davies, B. A.; Azmi, I. F.; Pashkova, N.; Payne, J. A.; Staffenhagen, J.; West, M.; Piper, R. C.; Odorizzi, G.; Katzmann, D.
10.1101/2020.07.27.223255 — cell biology — Posted on 2021-02-16
1907 Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells
Le Vasseur, M.; Friedman, J. R.; Jost, M.; Xu, J.; Yamada, J.; Kampmann, M.; Horlbeck, M. A.; Weissman, J. S.; Nunnari, J.
10.1101/2021.02.16.431450 — cell biology — Posted on 2021-02-16
1909 Live attenuated SARS-CoV-2 vaccine candidate: Protective immunity without serious lung lesions in Syrian hamsters
Okamura, S.; Kashiwabara, A.; Suzuki, H.; Ueno, S.; Miyazato, P.; Takekawa, S.; Kamitani, W.; Yamanishi, K.; Ebina, H.
10.1101/2021.02.15.430863 — microbiology — Posted on 2021-02-16
1912 Seasonal Dynamics in the Number and Composition of Coliform Bacteria in Drinking Water Reservoirs
Reitter, C.; Petzoldt, H.; Korth, A.; Schwab, F.; Stange, C.; Hambsch, B.; Tiehm, A.; Lagkouvardos, I.; Gescher, J.; Huegler, M.
10.1101/2021.02.16.428560 — microbiology — Posted on 2021-02-16
1913 Genomes of gut bacteria from Nasonia wasps shed light on phylosymbiosis and microbe-assisted hybrid breakdown
Cross, K. L.; Leigh, B. A.; Hatmaker, E. A.; Mikaelyan, A.; Miller, A. K.; Bordenstein, S. R.
10.1101/2021.02.13.431100 — microbiology — Posted on 2021-02-16
1914 Metabolic constraints on nitrogen fixation by rhizobia in legume nodules
Schulte, C. C. M.; Borah, K.; Wheatley, R.; Terpolilli, J.; Saalbach, G.; Crang, N.; de Groot, D. H.; Ratcliffe, R. G.; Kruger, N. J.; Papachristodoulou, A.; Poole, P. S.
10.1101/2021.02.16.431433 — microbiology — Posted on 2021-02-16
1915 Favourable antibody responses to human coronaviruses in children and adolescents with autoimmune rheumatic diseases
Deakin, C.; Cornish, G.; Ng, K.; Faulkner, N.; Bolland, W.; Panova, V.; Hope, J.; Rosa, A.; Harvey, R.; Hussain, S.; Earl, C.; Jebson, B.; Wilkinson, M.; Marshall, L.; O'Brien, K.; Rosser, L.; Radziszewska, A.; Peckham, H.; Heaney, J.; Rickman, H.; Paraskevopoulou, S.; Houlihan, C.; Spyer, M.; Gamblin, S.; Mccauley, J.; Nastouli, E.; Cherepanov, P.; Ciurtin, C.; Wedderburn, L.; Kassiotis, G.
10.1101/2021.02.15.431291 — immunology — Posted on 2021-02-16
1916 Characterization of humoral and SARS-CoV-2 specific T cell responses in people living with HIV
Alrubayyi, A.; Gea-Mallorqui, E.; Touizer, E.; Hameiri-Bowen, D.; Kopycinski, J.; Charlton, B.; Fisher-Pearson, N.; Muir, L.; Rosa, A.; Roustan, C.; Earl, C.; Cherepanov, P.; Pellegrino, P.; Waters, L.; Burns, F.; Kinloch, S.; Dong, T.; Dorrell, L.; Rowland-Jones, S.; McCoy, L. E.; Peppa, D.
10.1101/2021.02.15.431215 — immunology — Posted on 2021-02-16
1920 Generalization of motor learning in psychological space
Poh, E.; Al-Fawakhiri, N.; Tam, R.; Taylor, J. A.; McDougle, S. D.
10.1101/2021.02.09.430542 — neuroscience — Posted on 2021-02-16
1921 Analyses of infant vocal communication in mouse models of autism spectrum disorder using a novel unsupervised machine learning approach
Mai, L.; Kimura, R.; Hori, K.; Inada, H.; Kanno, K.; Matsuda, T.; Tachibana, R. O.; Yoshizaki, K.; Tucci, V.; Komaki, F.; Hoshino, M.; Osumi, N.
10.1101/738781 — neuroscience — Posted on 2021-02-16
1924 IRGM/Irgm1 Aggravates Progression of Atherosclerosis by Inducing Macrophage Apoptosis through the MAPK Signaling Pathway
Fang, S.; Sun, S.; Cai, H.; Hao, X.; Zou, X.; Wan, X.; Tian, J.; Li, Z.; Wang, S.; He, Z.; Huang, W.; Liang, C.; Zhang, Z.; Yang, L.; Tian, J.; Yu, B.; Sun, B.
10.1101/2021.01.06.425662 — pathology — Posted on 2021-02-16
1925 A glycan gate controls opening of the SARS-CoV-2 spike protein
Sztain, T. E.; Ahn, S.-H.; Bogetti, A. T.; Casalino, L.; Goldsmith, J. A.; McCool, R. S.; Kearns, F. L.; McCammon, J. A.; McLellan, J. S.; Chong, L.; Amaro, R. E.
10.1101/2021.02.15.431212 — biophysics — Posted on 2021-02-16
1929 Pharmacological inhibition of LSD1 triggers myeloid differentiation by targeting GSE1, a novel oncogene in AML
Nicosia, L.; Boffo, F. L.; Ceccacci, E.; Pallavicini, I.; Bedin, F.; Massignani, E.; Ravasio, R.; Minucci, S.; Bonaldi, T.
10.1101/2021.02.16.431315 — cancer biology — Posted on 2021-02-16
1930 Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells
Le Vasseur, M.; Friedman, J. R.; Jost, M.; Xu, J.; Yamada, J.; Kampmann, M.; Horlbeck, M. A.; Weissman, J. S.; Nunnari, J.
10.1101/2021.02.16.431450 — cell biology — Posted on 2021-02-16
1931 FRET-based screening in HEK293T identifies p38 MAPK and PKC inhibition as therapeutic targets for α-synuclein aggregation
Svanbergsson, A.; Ek, F.; Martinsson, I.; Rodo, J.; Liu, D.; Brandi, E.; Haikal, C.; Torres-Garcia, L.; Li, W.; Gouras, G.; Olsson, R.; Bjorklund, T.; Li, J.-Y.
10.1101/2021.02.16.431382 — molecular biology — Posted on 2021-02-16
1942 Magnetically stimulated cryogels to enhance osteogenic and chondrogenic differentiaton of stem cells
Odabas, S.; Tevlek, A.; Erenay, B.; Aydin, H. M.; Suloglu, A. K.; Yar Saglam, A. S.; Garipcan, B.
10.1101/2021.02.15.431106 — bioengineering — Posted on 2021-02-16
1945 The genome of the CTG(Ser1) yeast Scheffersomyces stipitis is plastic
Vega Estevez, S.; Armitage, A.; Bates, H. J.; Harrison, R. J.; Buscaino, A.
10.1101/2021.02.15.431239 — genomics — Posted on 2021-02-16
1947 On the phenology of protists: Recurrent patterns reveal seasonal variation of protistan (Rhizaria: Cercozoa, Endomyxa) communities in tree canopies
Walden, S.; Jauss, R.-T.; Feng, K.; Fiore-Donno, A. M.; Dumack, K.; Schaffer, S.; Wolf, R.; Schlegel, M.; Bonkowski, M.
10.1101/2021.02.15.431229 — ecology — Posted on 2021-02-16
1948 Anterior eye development in the brown anole, Anolis sagrei
Rasys, A. M.; Pau, S. H.; Irwin, K. E.; Luo, S.; Menke, D. B.; Lauderdale, J. D.
10.1101/2021.02.15.429783 — developmental biology — Posted on 2021-02-16
1952 Optimal Reinforcement Learning with Asymmetric Updating in Volatile Environments: a Simulation Study
Rostami Kandroodi, M.; Vahabie, A.-h.; Ahmadi, S.; Nadjar Araabi, B.; Nili Ahmadabadi, M.
10.1101/2021.02.15.431283 — neuroscience — Posted on 2021-02-16
1954 A hands-on tutorial on network and topological neuroscience
Centeno, E. G. Z.; Moreni, G.; Vriend, C.; Douw, L.; Santos, F. A. N.
10.1101/2021.02.15.431255 — neuroscience — Posted on 2021-02-16
1957 Exploring MEG brain fingerprints: evaluation, pitfalls and interpretations
Sareen, E.; Zahar, S.; Van De Ville, D.; Gupta, A.; Griffa, A.; Amico, E.
10.1101/2021.02.15.431253 — neuroscience — Posted on 2021-02-16
1958 A practical modification to a resting state fMRI protocol for improved characterization of cerebrovascular function
Stickland, R. C.; Zvolanek, K. M.; Moia, S. C.; Ayyagari, A.; Caballero-Gaudes, C.; Bright, M. G.
10.1101/2021.02.15.431289 — neuroscience — Posted on 2021-02-16
1959 Accuracy of the pneumatic method for estimating xylem vulnerability to embolism in temperate diffuse-porous tree species
Paligi, S. S.; Link, R. M.; Isaza, E.; Bittencourt, P.; Sarmento Cabral, J.; Jansen, S.; Oliveira, R. S.; Pereira, L.; Schuldt, B.
10.1101/2021.02.15.431295 — plant biology — Posted on 2021-02-16
1961 OBSTRUCTIVE APNEAS IN A MOUSE MODEL OF CONGENITAL CENTRAL HYPOVENTILATION SYNDROME
Madani, A.; Pitollat, G.; Sizun, E.; Cardoit, L.; Ringot, M.; BOURGEOIS, T.; Ramanantsoa, N.; Delclaux, C.; dauger, s.; d'Ortho, M.-P.; Thoby-Brisson, M.; GALLEGO, J.; Matrot, B.
10.1101/2021.02.15.431285 — physiology — Posted on 2021-02-16
1965 Dual MAPK and HDAC inhibition rewires the apoptotic rheostat to trigger colorectal cancer cell death
Jenkins, L. J.; Luk, I. Y.; Palmieri, M.; Fairlie, W. D.; Lee, E. F.; Schoffer, K. L.; Tan, T.; Ng, I.; Vukelic, N.; Tse, J. W.; Nightingale, R.; Alam, Z.; Iatropoulos, G.; Ernst, M.; Afshar-Sterle, S.; Desai, J.; Gibbs, P.; Sieber, O.; Dhillon, A.; Tebbutt, N. C.; Mariadason, J. M.
10.1101/2021.02.15.431252 — cancer biology — Posted on 2021-02-16
1968 Cuban history of CRF19 recombinant subtype of HIV-1
ZHUKOVA, A.; Voznica, J.; Davila Felipe, M.; To, T.-H.; Perez, L.; Martinez, Y.; Pintos, Y.; Mendez, M.; Gascuel, O.; Kouri, V.
10.1101/2021.02.15.431210 — bioinformatics — Posted on 2021-02-16
1971 Copper signaling promotes proteostasis and animal development via allosteric activation of ubiquitin E2D conjugases
Opazo, C. M.; Lotan, A.; Xiao, Z.; Zhang, B.; Greenough, M. A.; Lim, C. M.; Trytell, H.; Ramirez, A.; Ukuwela, A. A.; Mawal, C. H.; McKenna, J.; Saunders, D. N.; Burke, R.; Gooley, P. R.; Bush, A. I.
10.1101/2021.02.15.431211 — biochemistry — Posted on 2021-02-16
1973 The Metabesity Factor HMG20A Potentiates Astrocyte Survival and Reactivity Preserving Neuronal Integrity
Lorenzo, P. I.; Fuente-Martin, E.; Mellado-Gil, J. M.; Guerrero Martinez, J. A.; Cobo-Vuilleumier, N.; Comaills, V.; Martin Vazquez, E.; Romero-Zerbo, S. Y.; Munoz Franco, J.; Perez-Caballo, J. A.; Rivero-Canalejo, S.; Campo-Caro, A.; Lachaud, C. C.; Aguilar Diosdado, M.; Garcia Fuentes, E.; Martin-Montalvo, A.; Alvarez Dolado, M.; Martin, F.; Rojo Martinez, G.; Pozo, D.; Bermudez-Silva, F. J.; Reyes, J. C.; Gauthier, B. R.
10.1101/2021.02.15.431213 — cell biology — Posted on 2021-02-16
1974 Synthetic dysmobility screen unveils an integrated STK40-YAP-MAPK system driving cell migration
Yu, L.-Y.; Tseng, T.-J.; Lin, H.-C.; Lu, T.-X.; Tsai, C.-J.; Lin, Y.-C.; Hsu, C.-L.; Tsai, F.-C.
10.1101/2021.02.15.431287 — cell biology — Posted on 2021-02-16
1981 Typical somatomotor physiology of the hand is preserved in a patient with an amputated arm
van den Boom, M. A.; Miller, K. J.; Gregg, N. M.; Ojeda, G.; Lee, K. H.; Richner, T. J.; Ramsey, N. F.; Worrell, G. A.; Hermes, D.
10.1101/2021.02.12.430936 — neuroscience — Posted on 2021-02-16
1983 Paths to Oblivion: Common Neural Mechanisms of Anaesthesia and Disorders of Consciousness
Luppi, A. I.; Mediano, P. A. M.; Rosas, F. E.; Allanson, J.; Pickard, J. D.; Williams, G. B.; Craig, M. M.; Finoia, P.; Peattie, A. R. D.; Coppola, P.; Owen, A. M.; Naci, L.; Menon, D. K.; Bor, D.; Stamatakis, E. A.
10.1101/2021.02.14.431140 — neuroscience — Posted on 2021-02-16
1984 Fast Numerical Optimization for Genome Sequencing Data in Population Biobanks
Li, R.; Chang, C.; Tanigawa, Y.; Narasimhan, B.; Hastie, T.; Tibshirani, R. j.; Rivas, M. A.
10.1101/2021.02.14.431030 — bioinformatics — Posted on 2021-02-16
1986 Effects of kinship correction on inflation of genetic interaction statistics in commonly used mouse populations
Tyler, A.; Tyler, A. L.; El Kassaby, B.; Kolishovski, G.; Emerson, J.; Wells, A. E.; Mahoney, J. M.; Carter, G. W.
10.1101/2021.02.14.431191 — genetics — Posted on 2021-02-16
1987 What are housekeeping genes?
Joshi, C. J.; Ke, W.; Drangowska-Way, A.; O'Rourke, E. J.; Lewis, N. E.
10.1101/2021.02.14.431149 — evolutionary biology — Posted on 2021-02-16
1989 Chitinase 3-like-1 is a Therapeutic Target That Mediates the Effects of Aging in COVID-19
Kamle, S.; Ma, B.; He, C. H.; Akosman, B.; Zhou, Y.; Lee, C.-M.; El-Deiry, W. S.; Huntington, K.; Liang, O.; Machan, J. T.; Kang, M.-J.; Shin, H. J.; Mizoguchi, E.; Lee, C. G.; Elias, J. A.
10.1101/2021.01.05.425478 — immunology — Posted on 2021-02-16
1990 The essential role of Dnmt1 in gametogenesis in the large milkweed bug Oncopeltus fasciatus
Washington, J. T.; Cavender, K. R.; Amukamara, A. U.; McKinney, E. C.; Schmitz, R. J.; Moore, P. J.
10.1101/2020.07.23.218180 — evolutionary biology — Posted on 2021-02-16
1991 COVID-19 Disease Map, a computational knowledge repository of SARS-CoV-2 virus-host interaction mechanisms
Ostaszewski, M.; Niarakis, A.; Mazein, A.; Kuperstein, I.; Phair, R.; Orta-Resendiz, A.; Singh, V.; Aghamiri, S. S.; Acencio, M. L.; Glaab, E.; Ruepp, A.; Fobo, G.; Montrone, C.; Brauner, B.; Frishman, G.; Monraz Gomez, L. C.; Somers, J.; Hoch, M.; Gupta, S. K.; Scheel, J.; Borlinghaus, H.; Czauderna, T.; Schreiber, F.; Montagud, A.; Ponce de Leon, M.; Funahashi, A.; Hiki, Y.; Hiroi, N.; Yamada, T. G.; Drager, A.; Renz, A.; Naveez, M.; Bocskei, Z.; Messina, F.; Bornigen, D.; Fergusson, L.; Conti, M.; Rameil, M.; Nakonecnij, V.; Vanhoefer, J.; Schmiester, L.; Wang, M.; Ackerman, E. E.; Shoemake
10.1101/2020.10.26.356014 — systems biology — Posted on 2021-02-16
1993 Privacy preserving storage of sequenced genomic data
Hekel, R.; Budis, J.; Kucharik, M.; Radvanszky, J.; Pos, Z.; Szemes, T.
10.1101/2020.09.16.299594 — bioinformatics — Posted on 2021-02-16
1994 Sox2 controls neural stem cell self-renewal through a Fos-centered gene regulatory network
Pagin, M.; Pernebrink, M.; Giubbolini, S.; Barone, C.; Sambruni, G.; Zhu, Y.; Chiara, M.; Ottolenghi, S.; Pavesi, G.; Wei, C.-L.; Cantu, C.; Nicolis, S. K.
10.1101/2020.03.17.995621 — genetics — Posted on 2021-02-16
1996 SARS-CoV2 envelop proteins reshape the serological responses of COVID-19 patients
Martin, S.; Heslan, C.; Jegou, G.; Eriksson, L. A.; Le Gallo, M.; Thibault, V.; Chevet, E.; Godey, F.; Avril, T.
10.1101/2021.02.15.431237 — cell biology — Posted on 2021-02-16
1999 Development of a vaccine against the newly emerging COVID-19 virus based on the receptor binding domain displayed on virus-like particles
Zha, L.; Zhao, H.; Mohsen, M. O.; Hong, L.; Zhou, Y.; Li, Z.; Chen, H.; Liu, X.; Chang, X.; Zhang, J.; Li, D.; Wu, K.; Vogel, M.; Bachmann, M. F.; Wang, J.
10.1101/2020.05.06.079830 — immunology — Posted on 2021-02-16
2000 Database and deep learning toolbox for noise-optimized, generalized spike inference from calcium imaging data
Rupprecht, P.; Carta, S.; Hoffmann, A.; Echizen, M.; Blot, A.; Kwan, A. C.; Dan, Y.; Hofer, S. B.; Kitamura, K.; Helmchen, F.; Friedrich, R. W.
10.1101/2020.08.31.272450 — neuroscience — Posted on 2021-02-16
2003 Unravelling the Physiological Correlates of Mental Workload Variations in Tracking and Collision Prediction Tasks: Implications for Air Traffic Controllers
John, A. R.; Singh, A. K.; Do, T.-T. N.; Eidels, A.; Nalivaiko, E.; Gavgani, A. M.; Brown, S.; Bennett, M.; Lal, S.; Simpson, A. M.; Gustin, S. M.; Double, K.; Walker, F. R.; Kleitman, S.; Morley, J.; Lin, C.-T.
10.1101/2021.02.02.428702 — neuroscience — Posted on 2021-02-16
2007 Individual variability of neural computations in the primate retina
Shah, N.; Brackbill, N.; Samarakoon, R.; Rhoades, C.; Kling, A.; Sher, A.; Litke, A.; Singer, Y.; Shlens, J.; Chichilnisky, E. J.
10.1101/2021.02.14.431169 — neuroscience — Posted on 2021-02-16
2008 Environmental enrichment mitigates stroke-induced change in sharp-wave associated ripple characteristics
Ip, Z.; Rabiller, G.; He, J.-W.; Chavan, S.; Nishijima, Y.; Akamatsu, Y.; Liu, J.; Yazdan-Shahmorad, A.
10.1101/2021.02.12.431002 — neuroscience — Posted on 2021-02-16
2012 Sensitive and reproducible cell-free methylome quantification with synthetic spike-in controls
Wilson, S. L.; Shen, S. Y.; Harmon, L. M.; Burgener, J. M.; Bratman, S. V.; Triche, T. J.; De Carvalho, D. D.; Hoffman, M. M.
10.1101/2021.02.12.430289 — genomics — Posted on 2021-02-16
2013 Coupling spectral and resource-use complementarity in experimental grassland and forest communities
Schweiger, A. K.; Cavender-Bares, J.; Kothari, S.; Townsend, P. A.; Madritch, M. D.; Grossman, J. J.; Gholizadeh, H.; Wang, R.; Gamon, J. A.
10.1101/2020.04.24.060483 — ecology — Posted on 2021-02-16
2014 Id4 is required for normal ependymal cell development
Rocamonde, B.; Herranz-Perez, V.; Garcia-Verdugo, J.-M.; Huillard, E.
10.1101/2021.02.15.431205 — developmental biology — Posted on 2021-02-16
2015 Akkermansia muciniphila secretome promotes α-synuclein aggregation in enteroendocrine cells.
Amorim Neto, D. P.; Bosque, B. P.; de Godoy, J. V. P.; Rodrigues, P. V.; Meneses, D. D.; Tostes, K.; Tonoli, C. C. C.; Gonzalez-Billault, C.; Fonseca, M. d. C.
10.1101/2021.02.12.430931 — cell biology — Posted on 2021-02-16
2016 Differentially accessible Cdc4 phospho-degrons regulate Ctf19CCAN kinetochore subunit stability in mitosis
Westermann, S.; Böhm, M.; Killinger, K.; Dudziak, A.; Pant, P.; Jänen, K.; Hohoff, S.; Mechtler, K.; Örd, M.; Loog, M.; Sanchez-Garcia, E.
10.1101/2021.02.12.430993 — cell biology — Posted on 2021-02-16
2018 Dynamic association of IκBα to chromatin is regulated by acetylation and cleavage of histone H4
Espinosa, L.; Bertran, J.; Alvarez-Villanueva, D.; Floor, M.; Mulero, M. C.; Vert, A.; Guillen, Y.; Arce, S.; Batlle-Morera, L.; Villa-Freixa, J.; Ghosh, G.; Bigas, A.; Marruecos, L.
10.1101/2021.02.15.431217 — molecular biology — Posted on 2021-02-16
2020 Initial HCV infection of adult hepatocytes triggers a temporally structured transcriptional program containing diverse pro- and anti-viral elements
Tegtmeyer, B.; Vieyres, G.; Todt, D.; Lauber, C.; Ginkel, C.; Engelmann, M.; Herrmann, M.; Pfaller, C. K.; Vondran, F. W. R.; Broering, R.; Vafadarnejad, E.; Saliba, A.-E.; Puff, C.; Baumgärtner, W.; Miskey, C.; Ivics, Z.; Steinman, E.; Pietschmann, T.; Brown, R. J. P.
10.1101/2021.02.12.431054 — immunology — Posted on 2021-02-16
2021 Relation of inflammatory marker trajectories with frailty and aging in a 20-year longitudinal study
Samson, L. D.; Buisman, A.-M.; Ferreira, J. A.; Picavet, H. S. J.; Verschuren, W. M. M.; Boots, A. M. H.; Engelfriet, P.
10.1101/2021.02.10.430670 — immunology — Posted on 2021-02-16
2023 Generalization of motor learning in psychological space
Poh, E.; Al-Fawakhiri, N.; Tam, R.; Taylor, J. A.; McDougle, S. D.
10.1101/2021.02.09.430542 — neuroscience — Posted on 2021-02-16
2024 A multi-phase multi-objective genome-scale model shows diverse redox balance strategies in yeasts
Henriques, D.; Minebois, R.; Mendonza, S.; Macias, L. G.; Perez-Torrado, R.; barrio, E.; Teusink, B.; Querol, A.; Balsa-Canto, E.
10.1101/2021.02.11.430755 — systems biology — Posted on 2021-02-16
2026 Molecular View of Biomimetic Peptide in Action with Membrane
Koneru, J.; Prakashchand, D. D.; Dube, N.; Ghosh, P.; Mondal, J.
10.1101/2021.02.12.430925 — biophysics — Posted on 2021-02-16
2028 The Relationship between Birth Timing, Circuit Wiring, and Physiological ResponseProperties of Cerebellar Granule Cells
Shuster, A.; Wagner, M.; Pan-Doh, N.; Ren, J.; Grutzner, S.; Beier, K.; Kim, T.; Schnitzer, M.; Luo, L.
10.1101/2021.02.15.431339 — neuroscience — Posted on 2021-02-16
2032 Optical activation of TrkB neurotrophin receptor in mouse ventral hippocampus promotes plasticity and facilitates fear extinction
Umemori, J.; Didio, G.; Winkel, F.; Pou, M. L.; Harkki, J.; Russo, G. L.; Verie, M.; Antila, H.; Buj, C.; Taira, T.; Lauri, S. E.; Guirado, R.; Castren, E.
10.1101/2021.02.14.431126 — neuroscience — Posted on 2021-02-16
2033 StrainGE: A toolkit to track and characterize low-abundance strains in complex microbial communities
van Dijk, L. R.; Walker, B. J.; Straub, T. J.; Worby, C. J.; Grote, A.; Schreiber, H. L.; Anyansi, C.; Pickering, A. J.; Hultgren, S. J.; Manson, A. L.; Abeel, T.; Earl, A. M.
10.1101/2021.02.14.431013 — bioinformatics — Posted on 2021-02-16
2035 FORUM: Building a Knowledge Graph from public databases and scientific literature to extract associations between chemicals and diseases
Delmas, M.; Filangi, O.; Paulhe, N.; Vinson, F.; Duperier, C.; Garrier, W.; Saunier, P.- E.; Pitarch, Y.; Jourdan, F.; Giacomoni, F.; Frainay, C.
10.1101/2021.02.12.430944 — bioinformatics — Posted on 2021-02-16
2038 Rapid processing and quantitative evaluation of multicontrast EPImix scans for adaptive multimodal imaging
Vasa, F.; Hobday, H.; Stanyard, R. A.; Daws, R. E.; Giampietro, V.; ODaly, O.; Lythgoe, D. J.; Seidlitz, J.; Skare, S.; Williams, S. C. R.; Marquand, A. F.; Leech, R.; Cole, J. H.
10.1101/2021.02.12.430956 — neuroscience — Posted on 2021-02-16
2039 Revealing the Physiological Origin of Event-Related Potentials using Electrocorticography in Humans
Cho, H.; Schalk, G.; Adamek, M.; Moheimanian, L.; Coon, W. G.; Jun, S. C.; Wolpaw, J. R.; Brunner, P.
10.1101/2021.02.12.430921 — neuroscience — Posted on 2021-02-16
2041 PolyA: a tool for adjudicating competing annotations of biological sequences
Carey, K. M.; Hubley, R.; Lesica, G. T.; Olson, D.; Roddy, J. W.; Rosen, J.; Shingleton, A.; Smit, A. F.; Wheeler, T. J.
10.1101/2021.02.13.430877 — bioinformatics — Posted on 2021-02-16
2043 A Guide to Pre-Processing High-Throughput Animal Tracking Data
Gupte, P. R.; Beardsworth, C. E.; Spiegel, O.; Lourie, E.; Toledo, S.; Nathan, R.; Bijleveld, A. I.
10.1101/2020.12.15.422876 — ecology — Posted on 2021-02-16
2044 Helicase-Like Functions in Phosphate Loop Containing Beta-Alpha Polypeptides
Vyas, P.; Trofimyuk, O.; Longo, L. M.; Deshmukh, F. K.; Sharon, M.; Tawfik, D. S.
10.1101/2020.07.30.228619 — molecular biology — Posted on 2021-02-16
2047 Effect of ozone exposure on Amyotrophic Lateral Sclerosis (ALS) pathology using a mice model of TDP-43 proteinopathy
Rodriguez, A.; Ferrer-Donato, A.; Cabrera-Pinto, M.; Sesena, S.; Fernandez, P.; Aranda, A.; Fernandez-Martos, C. M.
10.1101/2021.02.12.430915 — neuroscience — Posted on 2021-02-16
2048 Dynamic Representation of the Subjective Value of Information
Kobayashi, K.; Lee, S.; Filipowicz, A. L. S.; McGaughey, K. D.; Kable, J. W.; Nassar, M. R.
10.1101/2021.02.12.431038 — neuroscience — Posted on 2021-02-16
2050 The Progenetix oncogenomic resource in 2021
Huang, Q.; Carrio Cordo, P.; Gao, B.; Paloots, R.; Baudis, M.
10.1101/2021.02.15.428237 — cancer biology — Posted on 2021-02-16
2052 GRIDSS2: comprehensive characterisation of somatic structural variation using single breakend variants and structural variant phasing
Cameron, D. L.; Baber, J.; Shale, C.; Valle-Inclan, J. E.; Besselink, N.; Cuppen, E.; Priestley, P.; Papenfuss, A. T.
10.1101/2020.07.09.196527 — bioinformatics — Posted on 2021-02-16
2053 Triku: a feature selection method based on nearest neighbors for single-cell data
Ascension, A. M.; Ibanez-Sole, O.; Inza, I.; Izeta, A.; Arauzo-Bravo, M. J.
10.1101/2021.02.12.430764 — bioinformatics — Posted on 2021-02-16
2055 NDI: A platform-independent data interface and database for neuroscience physiology and imaging experiments
Garcia Murillo, D.; Rogovin, O.; Zhao, Y.; Chen, S.; Wang, Z.; Keeley, Z. C.; Shin, D. I.; Suarez Casanova, V. M.; Zhu, Y.; Martin, L.; Papaemmanouil, O.; Van Hooser, S. D.
10.1101/2020.05.13.093542 — neuroscience — Posted on 2021-02-16
2064 Impaired clock gene expression and abnormal diurnal regulation of hippocampal inhibitory transmission and spatial memory in a mouse model of Alzheimers disease
Fusilier, A. R.; Davis, J. A.; Paul, J. R.; Yates, S. D.; McMeekin, L. J.; Goode, L. K.; Mokashi, M. V.; van Groen, T.; Cowell, R. M.; McMahon, L. L.; Roberson, E. D.; Gamble, K. L.
10.1101/2021.02.12.430852 — neuroscience — Posted on 2021-02-15
2075 Shared genetic influences on resting-state functional networks of the brain
Guimaraes, J. P. O. F. T.; Sprooten, E.; Beckmann, C. F.; Franke, B.; Bralten, J.
10.1101/2021.02.15.431231 — neuroscience — Posted on 2021-02-15
2076 Region-specific maladaptive gray matter myelination is associated with differential susceptibility to stress-induced behavior in male rodents and humans
Long, K. L. P.; Chao, L. L.; Kazama, Y.; An, A.; Hu, K. Y.; Peretz, L.; Muller, D. C. Y.; Roan, V. D.; Misra, R.; Toth, C. E.; Breton, J. M.; Casazza, W.; Mostafavi, S. M.; Huber, B. R.; Woodward, S. H.; Neylan, T. C.; Kaufer, D.
10.1101/2021.02.15.431176 — neuroscience — Posted on 2021-02-15
2078 Clinical and Genetic insights in a tertiary care center cohort of patients with bicuspid aortic valve
THERON, A.; Touil, A.; Resseguier, N.; Collod-Beroud, G.; Norscini, G.; Simoni, A.-S.; Odelin, G.; HABIB, G.; Collart, F.; Zaffran, S.; Avierinos, J.-F.
10.1101/2021.02.15.431243 — genetics — Posted on 2021-02-15
2080 Soluble guanylate cyclase stimulation mitigates skeletal and cardiac muscle dysfunction in a mdx model of Duchenne muscular dystrophy
Zhang, L.; Xu, Y.; Yousefi, K.; Irion, C. I.; Alvarez, R. A.; Krishnan, S. M.; Stasch, J.-P.; Martinez, E. C.; Buys, E. S.; Sandner, P.; Shehadeh, L. A.; Percival, J. M.
10.1101/2021.02.14.431156 — physiology — Posted on 2021-02-15
2081 Expanding the MECP2 network using comparative genomics reveals potential therapeutic targets for Rett syndrome
Unterman, I.; Bloch, I.; Cazacu, S.; Kazimirsky, G.; Berman, B. P.; Ben-Zeev, B.; Brodie, C.; Tabach, Y.
10.1101/2021.02.14.431162 — bioinformatics — Posted on 2021-02-15
2082 Long-reads are revolutionizing 20 years of insect genome sequencing
Hotaling, S.; Sproul, J. S.; Heckenhauer, J.; Powell, A.; Larracuente, A. L.; Pauls, S. U.; Kelley, J. L.; Frandsen, P. B.
10.1101/2021.02.14.431146 — genomics — Posted on 2021-02-15
2092 Broad-spectrum antiviral activity of 3D8, a nucleic acid-hydrolyzing single chain variable fragment (scFv), targeting SARS-CoV-2 and multiple coronaviruses in vitro
Lee, G.; Budhathoki, S.; Lee, G.-Y.; Oh, K.-j.; Ham, Y. K.; Kim, Y. J.; Lim, Y. R.; Hoang, P. T.; Lee, Y.; Lim, S.-W.; Kim, J.-M.; Cho, S.; Kim, T.-H.; Song, J.-W.; Lee, S.; Kim, W.-K.
10.1101/2020.11.25.398909 — microbiology — Posted on 2021-02-15
2093 Assessment of the reproducibility and inter-site transferability of the murine direct splenocyte mycobacterial growth inhibition assay (MGIA)
Tanner, R.; Zelmer, A.; Painter, H.; Stylianou, E.; Pinpathomrat, N.; Harrington-Kandt, R.; Biffar, L.; Brennan, M. J.; McShane, H.; Fletcher, H. A.
10.1101/2021.02.14.431105 — immunology — Posted on 2021-02-15
2095 c-Rel is required for IL-33-dependent activation of ILC2s
Zaini, A.; Fulford, T.; Grumont, R.; Runting, J.; Rodrigues, G.; Ng, J.; Gerondakis, S.; Zaph, C.; Scheer, S.
10.1101/2021.02.14.431188 — immunology — Posted on 2021-02-15
2096 Analysis of Hippocampal Subfields in Sickle Cell Disease Using Ultrahigh Field MRI
Santini, T.; Koo, M.; Farhat, N.; Campos, V. P.; Alkhateeb, S.; Vieira, M. A. C.; Butters, M. A.; Rosano, C.; Aizenstein, H. J.; Mettenburg, J.; Novelli, E. M.; Ibrahim, T. S.
10.1101/2020.11.10.377564 — neuroscience — Posted on 2021-02-15
2098 GABA levels in ventral visual cortex decline with age and are associated with neural distinctiveness
Chamberlain, J. D.; Gagnon, H.; Lalwani, P.; Cassady, K. E.; Simmonite, M.; Seidler, R. D.; Taylor, S. F.; Weissman, D. H.; Park, D. C.; Polk, T. A.
10.1101/743674 — neuroscience — Posted on 2021-02-15
2101 Genetic and gene expression analysis of flowering time regulation by light quality in lentil
Yuan, H. Y.; Caron, C. T.; Ramsay, L.; Fratini, R.; Perez de la Vega, M.; Vandenberg, A.; Weller, J. L.; Bett, K. E.
10.1101/2021.02.14.429948 — plant biology — Posted on 2021-02-15
2103 Spatially Interacting Phosphorylation Sites and Mutations in Cancer
Huang, K.-l.; Scott, A.; Zhou, D. C.; Wang, L.-b.; Weerasinghe, A.; Elmas, A.; Liu, R.; Wu, Y.; Wendl, M.; Wyczalkowski, M.; Baral, J.; Sengupta, S.; Lai, C.-W.; Ruggles, K.; Payne, S.; Raphael, B.; Fenyo, D.; Chen, K.; Mills, G.; Ding, L.
10.1101/2021.02.14.431184 — bioinformatics — Posted on 2021-02-15
2107 Subtype-specific and co-occurring genetic alterations in B-cell non-Hodgkin lymphoma
Ma, M. C. J.; Tadros, S.; Bouska, A.; Heavican, T.; Yang, H.; Deng, Q.; Moore, D.; Akhter, A.; Hartert, K.; Jain, N.; Showell, J.; Ghosh, S.; Street, L.; Davidson, M.; Carey, C.; Tobin, J.; Perumal, D.; Vose, J.; Lunning, M.; Sohani, A.; Chen, B.; Buckley, S.; Nastoupil, L.; Davis, R. E.; Westin, J.; Fowler, N.; Parekh, S.; Gandhi, M.; Neelapu, S.; Stewart, D.; Iqbal, J.; Rodig, S.; Mansoor, A.; Green, M.
10.1101/674259 — genomics — Posted on 2021-02-15
2109 Genome-wide Identification of the Genetic Basis of Amyotrophic Lateral Sclerosis
Zhang, S.; Cooper-Knock, J.; Weimer, A. K.; Shi, M.; Moll, T.; Harvey, C.; Nezhad, H. G.; Franklin, J.; Souza, C. d. S.; Wang, C.; Li, J.; Elhaik, E.; Eitan, C.; Hornstein, E.; Kenna, K. P.; Project MinE Sequencing Consortium, ; Veldink, J.; Ferraiuolo, L.; Shaw, P. J.; Snyder, M. P.
10.1101/2020.11.14.382606 — genomics — Posted on 2021-02-15
2110 Different evolutionary trends form the twilight zone of the bacterial pan-genome
Horesh, G.; Taylor-Brown, A.; McGimpsey, S.; Lasalle, F.; Corander, J.; Heinz, E.; Thomson, N. R.
10.1101/2021.02.15.431222 — genomics — Posted on 2021-02-15
2111 Calling differential DNA methylation at cell-type resolution: addressing misconceptions and best practices
Rahmani, E.; Jew, B.; Schweiger, R.; Rhead, B.; Criswell, L. A.; Barcellos, L. F.; Eskin, E.; Rosset, S.; Sankararaman, S.; Halperin, E.
10.1101/2021.02.14.431168 — genomics — Posted on 2021-02-15
2112 Broad geographic sampling reveals predictable, pervasive, and strong seasonal adaptation in Drosophila
Machado, H.; Bergland, A. O.; Taylor, R.; Tilk, S.; Behrman, E.; Dyer, K.; Fabian, D.; Flatt, T.; Gonzalez, J.; Karasov, T.; Kozeretska, I.; Lazzaro, B. P.; Merritt, T.; Pool, J.; O'Brien, K.; Rajpurohit, S.; Roy, P.; Schaeffer, S.; Serga, S.; Schmidt, P.; Petrov, D.
10.1101/337543 — evolutionary biology — Posted on 2021-02-15
2113 Gene co-expression network reveals highly conserved, well-regulated anti-ageing mechanisms in old ant queens.
Harrison, M. C.; Jaimes Nino, L. M.; Almeida Rodrigues, M.; Ryll, J.; Flatt, T.; Oettler, J.; Bornberg-Bauer, E.
10.1101/2021.02.14.431190 — evolutionary biology — Posted on 2021-02-15
2115 A global indicator of utilised wildlife populations: regional trends and the impact of management
McRae, L.; Freeman, R.; Geldmann, J.; Moss, G. B.; Kjaer-Hansen, L.; Burgess, N. D.
10.1101/2020.11.02.365031 — ecology — Posted on 2021-02-15
2117 Are irrigated urban trees more sensitive to light and temperature than water?
Griffin, K. L.; Harris, T. G.; Bruner, S.; McKenzie, P. F.; Hise, J.
10.1101/2020.10.29.361121 — ecology — Posted on 2021-02-15
2120 SARS-CoV2 envelop proteins reshape the serological responses of COVID-19 patients
Martin, S.; Heslan, C.; Jegou, G.; Eriksson, L. A.; Le Gallo, M.; Thibault, V.; Chevet, E.; Avril, T.
10.1101/2021.02.15.431237 — cell biology — Posted on 2021-02-15
2121 Bromodomain and Extraterminal Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV-2 Infection (Pre-Clinical)
Mills, R. J.; Humphrey, S. J.; Fortuna, P. R.; Lor, M.; Foster, S. R.; Quaife-Ryan, G. A.; Johnston, R. L.; Dumenil, T.; Bishop, C.; Ruraraju, R.; Rawle, D. J.; Le, T.; Zhao, W.; Lee, L.; Mackenzie-Kludas, C.; Mehdiabadi, N. R.; Halliday, C.; Gilham, D.; Fu, L.; Nicholls, S. J.; Johansson, J.; Sweeney, M.; Wong, N. C. W.; Kulikowski, E.; Sokolowski, K.; Tse, B. W. C.; Devilee, L.; Voges, H. K.; Reynolds, L. T.; Krumeich, S.; Mathieson, E.; Abu-Bonsrah, D.; Karavendzas, K.; Griffen, B.; Titmarsh, D. M.; Elliott, D. A.; McMahon, J. H.; Suhrbier, A.; Subbarao, K.; Porrello, E. R.; Smyth, M. J.; E
10.1101/2020.08.23.258574 — cell biology — Posted on 2021-02-15
2123 Parasite co-opts a ubiquitin receptor to induce a plethora of developmental changes
Huang, W.; MacLean, A.; Sugio, A.; Maqbool, A.; Busscher, M.; Cho, S.-T.; Kamoun, S.; Kuo, C.-H.; Immink, R. G. H.; Hogenhout, S. A.
10.1101/2021.02.15.430920 — molecular biology — Posted on 2021-02-15
2127 In-depth single-cell analysis of translation-competent HIV-1 reservoirs identifies cellular sources of plasma viremia
Cole, B.; Lambrechts, L.; Gantner, P.; Noppe, Y.; Bonine, N.; Witkowski, W.; Chen, L. H.; Palmer, S.; Mullins, J. I.; Chomont, N.; Pardons, M.; Vandekerckhove, L.
10.1101/2021.02.15.431218 — microbiology — Posted on 2021-02-15
2130 Phyletic distribution and diversification of the Phage Shock Protein stress response system in bacteria and archaea
Popp, P. F.; Gumerov, V. M.; Andrianova, E. P.; Bewersdorf, L.; Mascher, T.; Jouline, I.; Wolf, D.
10.1101/2021.02.15.431232 — microbiology — Posted on 2021-02-15
2131 The dynamic transition of persistence towards the VBNC state during stationary phase is driven by protein aggregation
Dewachter, L.; Bollen, C.; Wilmaerts, D.; Louwagie, E.; Herpels, P.; Matthay, P.; Khodaparast, L.; Khodaparast, L.; Rousseau, F.; Schymkowitz, J.; Michiels, J.
10.1101/2021.02.15.431274 — microbiology — Posted on 2021-02-15
2132 PD-1-induced T cell exhaustion is controlled by a Drp1-dependent mechanism
Simula, L.; Cancila, V.; Antonucci, Y.; Colamatteo, A.; Procaccini, C.; Matarese, G.; Tripodo, C.; Campello, S.
10.1101/2020.07.14.200592 — immunology — Posted on 2021-02-15
2134 NMDA receptor-BK channel coupling regulates synaptic plasticity in the barrel cortex
Gomez, R.; Maglio, L. E.; Gonzalez-Hernandez, A. J.; Rivero-Perez, B.; Bartolome-Martin, D.; Giraldez, T.
10.1101/2020.12.30.424719 — neuroscience — Posted on 2021-02-15
2137 CGRP-receptor family reveals endogenous GPCR agonist bias and its significance in primary human cardiovascular cells
Clark, A.; Mullooly, N.; Safitri, D.; Harris, M.; de Vries, T.; Van Den Brink, A. M.; Poyner, D. R.; Gianni, D.; Wigglesworth, M.; Ladds, G.
10.1101/2020.12.21.423730 — pharmacology and toxicology — Posted on 2021-02-15
2138 Quantifying and Mitigating Motor Phenotypes Induced by Antisense Oligonucleotides in the Central Nervous System
Moazami, M. P.; Rembetsy-Brown, J. M.; Wang, F.; Krishnamurthy, P. M.; Weiss, A.; Marosfoi, M.; King, R. M.; Motwani, M.; Gray-Edwards, H.; Fitzgerald, K. A.; Brown, R. H.; Watts, J. K.
10.1101/2021.02.14.431096 — pharmacology and toxicology — Posted on 2021-02-15
2143 Traces of transposable element in genome dark matter co-opted by flowering gene regulation networks.
Baud, A.; Wan, M.; Nouaud, D.; Francillonne, N.; Anxolabehere, D.; Quesneville, H.
10.1101/547877 — genomics — Posted on 2021-02-15
2144 SARS-CoV-2 and SARS-CoV spike-mediated cell-cell fusion differ in the requirements for receptor expression and proteolytic activation
Hörnich, B. F.; Grosskopf, A. K.; Schlagowski, S.; Tenbusch, M.; Kleine-Weber, H.; Neipel, F.; Stahl-Hennig, C.; Hahn, A. S.
10.1101/2020.07.25.221135 — microbiology — Posted on 2021-02-15
2145 Cerebellar lesions disrupt spatial and temporal visual attention.
Craig, B. T.; Morrill, A.; Anderson, B.; Danckert, J.; Striemer, C. L.
10.1101/822635 — neuroscience — Posted on 2021-02-15
2147 A benchmarking of human mitochondrial DNA haplogroup classifiers from whole-genome and whole-exome sequence data
Garcia-Olivares, V.; Munoz-Barrera, A.; Lorenzo-Salazar, J. M.; Zaragoza-Trello, C.; Rubio-Rodriguez, L. A.; Diaz-de Usera, A.; Jaspez, D.; Inigo-Campos, A.; Gonzalez-Montelongo, R.; Flores, C.
10.1101/2021.02.11.430775 — genomics — Posted on 2021-02-15
2149 Sequential infection with influenza A virus followed by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to more severe disease and encephalitis in a mouse model of COVID-19.
Clark, J. J.; Penrice-Randal, R.; Sharma, P.; Kipar, A.; Dong, X.; Pennington, S.; Marriott, A. E.; Colombo, S.; Davidson, A. D.; Kavanagh Williamson, M.; Matthews, D. A.; Turtle, L.; Prince, T.; Hughes, G.; Patterson, E. I.; Shawli, G.; Subramaniam, K.; Sharp, J.; McLaughlin, L.; Zhou, E.-M.; Turner, J. D.; Biagini, G.; Owen, A.; Hiscox, J. A.; Stewart, J. P.
10.1101/2020.10.13.334532 — microbiology — Posted on 2021-02-15
2150 Immunological and cardio-vascular pathologies associated with SARS-CoV-2 infection in golden syrian hamster
Rizvi, Z. A.; Dalal, R.; Sadhu, S.; Kumar, Y.; Shrivastava, T.; Gupta, S. K.; Aggarwal, S.; Tripathy, M. R.; Yadav, A. K.; Medigeshi, G. R.; Pandey, A. K.; Samal, S.; Asthana, S.; Awasthi, A.
10.1101/2021.01.11.426080 — microbiology — Posted on 2021-02-15
2151 Complete Protection of Nasal and Lung Airways Against SARS-CoV-2 Challenge by Antibody Plus Th1 Dominant N- and S-Specific T-Cell Responses to Subcutaneous Prime and Thermally-Stable Oral Boost Bivalent hAd5 Vaccination in an NHP Study
Gabitzsch, E.; Safrit, J. T.; Verma, M.; Rice, A.; Sieling, P.; Zakin, L.; Shin, A.; Morimoto, B.; Adisetiyo, H.; Wong, R.; Bezawada, A.; Dinkins, K.; Balint, J.; Peykov, V.; Garban, H.; Liu, P.; Bacon, A.; Drew, J.; Sanford, D. C.; Spilman, P.; Sender, L.; Rabizadeh, S.; Niazi, K.; Soon-Shiong, P.
10.1101/2020.12.08.416297 — immunology — Posted on 2021-02-15
2153 Pulled Diversification Rates, Lineages-Through-Time Plots and Modern Macroevolutionary Modelling
Helmstetter, A. J.; Glemin, S.; Kafer, J.; Zenil-Ferguson, R.; Sauquet, H.; de Boer, H.; Dagallier, L.-P. M.; Mazet, N.; Reboud, E. L.; Couvreur, T. L.; Condamine, F. L.
10.1101/2021.01.04.424672 — evolutionary biology — Posted on 2021-02-15
2156 The Progenetix oncogenomic resource in 2021
Huang, Q.; Carrio Cordo, P.; Gao, B.; Paloots, R.; Baudis, M.
10.1101/2021.02.15.428237 — cancer biology — Posted on 2021-02-15
2158 A developmental framework linking neurogenesis and circuit formation in the Drosophila CNS
Mark, B.; Lai, S.-L.; Arzan Zarin, A.; Manning, L.; Litwin-Kumar, A.; Cardona, A.; Truman, J. W.; Doe, C. Q.
10.1101/617936 — neuroscience — Posted on 2021-02-15
2161 ALG-097111, a potent and selective SARS-CoV-2 3-chymotrypsin-like cysteine protease inhibitor exhibits in vivo efficacy in a Syrian Hamster model
Vandyck, K.; Abdelnabi, R.; Gupta, K.; Jochmans, D.; Jekle, A.; Deval, J.; Misner, D.; Bardiot, D.; Foo, C. S.; Liu, C.; Ren, S.; Beigelman, L.; Blatt, L. M.; Boland, S.; Vangeel, L.; Dejonghe, S.; Chaltin, P.; Marchand, A.; Serebryany, V.; Stoycheva, A.; Chanda, S.; Symons, J. A.; Raboisson, P.; Neyts, J.
10.1101/2021.02.14.431129 — microbiology — Posted on 2021-02-15
2163 Potent, Novel SARS-CoV-2 PLpro Inhibitors Block Viral Replication in Monkey and Human Cell Cultures
Shen, Z.; Ratia, K.; Cooper, L.; Kong, D.; Lee, H.; Kwon, Y.; Li, Y.; Alqarni, S.; Huang, F.; Dubrovskyi, O.; Rong, L.; Thatcher, G. R.; XIONG, R.
10.1101/2021.02.13.431008 — microbiology — Posted on 2021-02-15
2164 Direct activation of endothelial cells by SARS-CoV-2 nucleocapsid protein is blocked by Simvastatin
Qian, Y.; Lei, T.; Patel, P.; Lee, C.; Monaghan-Nichols, P.; Xin, H.-B.; Qiu, J.; Fu, M.
10.1101/2021.02.14.431174 — immunology — Posted on 2021-02-15
2165 Impact of Binge Drinking During College on Resting State Functional Connectivity
Tong, T. T.; Vaidya, J. G.; Kramer, J. R.; Kuperman, S.; Langbehn, D. R.; OLeary, D. S.
10.1101/2021.02.09.430381 — neuroscience — Posted on 2021-02-15
2169 Protocell Arrays for Simultaneous Detection of Diverse Analytes
Zhang, Y.; Kojima, T.; Kim, G.-A.; McNerney, M. P.; Takayama, S.; Styczynski, M. P.
10.1101/2021.02.13.431022 — synthetic biology — Posted on 2021-02-15
2170 MSA Transformer
Rao, R.; Liu, J.; Verkuil, R.; Meier, J.; Canny, J. F.; Abbeel, P.; Sercu, T.; Rives, A.
10.1101/2021.02.12.430858 — synthetic biology — Posted on 2021-02-15
2171 Genie: An interactive real-time simulation for teaching genetic drift
Castillo, A. I.; Roos, B. H.; Rosenberg, M. S.; Cartwright, R. A.; Wilson, M. A.
10.1101/268672 — scientific communication and education — Posted on 2021-02-15
2172 GABA plays a key role in plant acclimation to a combination of high light and heat stress
Balfagon, D.; Gomez-Cadenas, A.; Rambla, J. L.; Granell, A.; de Ollas, C.; Mittler, R.; I Zandalinas, S.
10.1101/2021.02.13.431103 — plant biology — Posted on 2021-02-14
2173 Subcellular dynamics studies reveal how tissue-specific distribution patterns of iron are established in developing wheat grains
Sheraz, S.; Wan, Y.; Venter, E.; Verma, S. K.; Xiong, Q.; Waites, J.; Connorton, J. M.; Shewry, P. R.; Moore, K. L.; Balk, J.
10.1101/2021.02.14.431124 — plant biology — Posted on 2021-02-14
2174 Endothelial alpha globin is a nitrite reductase
Keller, T. C. S.; Keller, A. S.; Broseghini-Filho, G. B.; Butcher, J. T.; Askew Page, H. R.; Islam, A.; Tan, Z. Y.; DeLalio, L. J.; Lechauve, C.; Brooks, S. D.; Sharma, P.; Hong, K.; Xu, W.; Padilha, A. S.; Ruddiman, C. A.; Best, A. K.; Macal, E.; Kim-Shapiro, D.; Christ, G.; Yan, Z.; Cortese-Krott, M. M.; Ricart, K.; Patel, R. P.; Bender, T. P.; Sonkusare, S. K.; Weiss, M. J.; Ackerman, H.; Columbus, L.; Isakson, B. E.
10.1101/2021.02.12.430954 — physiology — Posted on 2021-02-14
2175 Impact of an oral amino acid provision on Achilles peritendinous amino acid concentrations in young and older adults
Carroll, C. C.; Couture, S.; Farino, D. O.; Patel, S. H.; Campbell, N. W.; Stout, J.; Sabbaghi, A.
10.1101/2021.02.12.430945 — physiology — Posted on 2021-02-14
2177 In vitro efficacy of Artemisia extracts against SARS-CoV-2
Nie, C.; Trimpert, J.; Moon, S.; Haag, R.; Gilmore, K.; Kaufer, B. B.; Seeberger, P. H.
10.1101/2021.02.14.431122 — pharmacology and toxicology — Posted on 2021-02-15
2178 Epigenetic changes with age primes mammary luminal epithelia for cancer initiation
Sayaman, R. W.; Miyano, M.; Senapati, P.; Shalabi, S.; Zirbes, A.; Todhunter, M. E.; Seewaldt, V.; Neuhausen, S. L.; Stampfer, M. R.; Schones, D. E.; LaBarge, M. A.
10.1101/2021.02.12.430777 — cancer biology — Posted on 2021-02-13
2180 EZH2 Engages TGFβ Signaling to Promote Breast Cancer Bone Metastasis via Integrin β1-FAK Activation
Zhang, L.; Qu, J.; Qi, Y.; Huang, Y.-W.; Zhou, Z.; Li, P.; Yao, J.; Huang, B.; Zhang, S.; Yu, D.
10.1101/2021.02.14.431151 — cancer biology — Posted on 2021-02-14
2181 APOBEC mutagenesis inhibits breast cancer growth through induction of a T cell-mediated antitumor immune response
DiMarco, A. V.; Qin, X.; Van Alsten, S.; McKinney, B.; Garcia, N. M. G.; Force, J.; Hanks, B. A.; Troester, M. A.; Owzar, K.; Xie, J.; Alvarez, J. V.
10.1101/2021.02.13.431068 — cancer biology — Posted on 2021-02-14
2182 The APOBEC3A deaminase drives episodic mutagenesis in cancer cells
Petljak, M.; Chu, K.; Dananberg, A.; Bergstrom, E. N.; von Morgen, P.; Alexandrov, L.; Stratton, M. R.; Maciejowski, J.
10.1101/2021.02.14.431145 — cancer biology — Posted on 2021-02-14
2184 Metabolomics, Transcriptomics and Functional Glycomics Reveals Bladder Cancer Cells Plasticity and Enhanced Aggressiveness Facing Hypoxia and Glucose Deprivation
Peixoto, A.; Freitas, R. A.; Ferreira, D. A.; Relvas-Santos, M.; Paulo, P.; Cardoso, M.; Soares, J.; Gaiteiro, C. A.; Palmeira, C.; Teixeira, F.; Ferreira, R.; Oliveira, M. J.; Silva, A.; Santos, L. L.; Ferreira, J. A.
10.1101/2021.02.14.431133 — cancer biology — Posted on 2021-02-14
2186 Cancer phylogenetics using single-cell RNA-seq data
Moravec, J. C.; Lanfear, R.; Spector, D.; Diermeier, S.; Gavryushkin, A.
10.1101/2021.01.07.425804 — cancer biology — Posted on 2021-02-14
2188 BET Inhibition Enhances TNF Mediated Anti-Tumor Immunity
Wellinger, L. C.; Hogg, S. J.; Newman, D. M.; Friess, T.; Geiss, D.; Michie, J.; Ramsbottom, K. M.; Bacac, M.; Fauti, T.; Marbach, D.; Jarassier, L.; Thienger, P.; Paehler, A.; Cluse, L. A.; Kearney, C. J.; Vervoort, S. J.; Oliaro, J.; Shortt, J.; Ruefli-Brasse, A.; Rohle, D.; Johnstone, R. W.
10.1101/2021.02.15.429851 — cancer biology — Posted on 2021-02-15
2189 Tumor expressed CD95 causes suppression of anti-tumor activity of NK cells in a model of triple negative breast cancer
Qadir, A. S.; Guegan, J. P.; Ginestier, C.; Chaibi, A.; Bessede, A.; Charafe-Jauffret, E.; Macario, M.; Lavoue, V.; de la Motte Rouge, T.; Law, C.; Vilker, J.; Wang, H.; Stroup, E.; Schipma, M. J.; Bridgeman, B.; Murmann, A. E.; Ji, Z.; Legembre, P.; Peter, M. E.
10.1101/2021.02.12.431011 — cancer biology — Posted on 2021-02-15
2190 DARPP-32 promotes ERBB3-mediated resistance to molecular targeted therapy in EGFR-mutated lung adenocarcinoma
Alam, S. K.; Zhang, Y.; Wang, L.; Zhu, Z.; Hernandez, C. E.; Zhou, Y.; Yang, N.; Lei, J.; Chen, X.; Zeng, L.; Klein, M. A.; Hoeppner, L. H.
10.1101/2021.02.12.430856 — cancer biology — Posted on 2021-02-15
2191 A Brownian ratchet model for DNA loop extrusion by the cohesin complex
Higashi, T. L.; Tang, M.; Pobegalov, G.; Uhlmann, F.; Molodtsov, M.
10.1101/2021.02.14.431132 — biophysics — Posted on 2021-02-14
2198 Structural and thermodynamic analyses of human TMED1 (p24γ1) Golgi dynamics
Mota, D. C. A. M.; Mori, R. M.; Batista, M. R. B.; Basso, L. G. M.; Cardoso, I. A.; Nonato, M. C.; Costa-Filho, A. J.; Mendes, L. F. S.
10.1101/2021.02.13.431076 — biophysics — Posted on 2021-02-14
2201 Tyrosine 121 moves revealing a druggable pocket that couples catalysis to ATP-binding in serine racemase
Koulouris, C. R.; Gardiner, S. E.; Harris, T. K.; Elvers, K. T.; Roe, S. M.; Gillespie, J. A.; Ward, S. E.; Grubisha, O.; Nicholls, R. A.; Atack, J. R.; Bax, B. D.
10.1101/2021.02.12.430960 — biophysics — Posted on 2021-02-15
2209 Domain adaptive neural networks improvecross-species prediction of transcription factor binding
Cochran, K.; Srivastava, D.; Shrikumar, A.; Balsubramani, A.; Kundaje, A.; Mahony, S.
10.1101/2021.02.13.431115 — bioinformatics — Posted on 2021-02-14
2211 Protein yield is tunable by synonymous codon changes of translation initiation sites
Bhandari, B. K.; Lim, C. S.; Remus, D. M.; Chen, A.; van Dolleweerd, C.; Gardner, P. P.
10.1101/726752 — bioinformatics — Posted on 2021-02-14
2212 Comprehensive generation, visualization, and reporting of quality control metrics for single-cell RNA sequencing data
Hong, R.; Koga, Y.; Bandyadka, S.; Leshchyk, A.; Wang, Z.; Alabdullatif, S.; Wang, Y.; Akavoor, V.; Cao, X.; Sarfraz, I.; Jansen, F.; Johnson, W. E.; Yajima, M.; Campbell, J. D.
10.1101/2020.11.16.385328 — bioinformatics — Posted on 2021-02-14
2213 RatsPub: a webservice aided by deep learning to mine PubMed for addiction-related genes
Gunturkun, M. H.; Flashner, E.; Wang, T.; Mulligan, M. K.; Williams, R. W.; Prins, P.; Chen, H.
10.1101/2020.09.17.297358 — bioinformatics — Posted on 2021-02-14
2215 SearcHPV: a novel approach to identify and assemble human papillomavirus-host genomic integration events in cancer
Pinatti, L. M.; Gu, W.; Wang, Y.; El Hossiny, A.; Bhangale, A. D.; Brummel, C. V.; Carey, T. E.; Mills, R. E.; Brenner, J. C.
10.1101/2021.02.11.430847 — bioinformatics — Posted on 2021-02-15
2222 Computational Simulation of 4-D Micro-Circular Network in Zebrafish Tail Amputation and Regeneration
Roustaei, M.; Baek, K. I.; Wang, Z.; Cavallero, S.; Satta, S.; Lai, A.; O'Donnell, R.; Vedula, V.; Ding, Y.; Marsden, A. L.; Hsiai, T.
10.1101/2021.02.10.430654 — bioengineering — Posted on 2021-02-14
2224 Aggregation-induced emission dots assisted non-invasive fluorescence hysterography in near-infrared IIb window
Yu, X.; Ying, Y.; Feng, Z.; Qi, J.; Zheng, J.; Zhang, Y.; Liu, J.; Qian, J.; Tang, B. Z.; Zhang, D.
10.1101/2021.02.14.431069 — bioengineering — Posted on 2021-02-14
2226 Mesenchymal stem cells carry and transport clusters of cancer cells
Zarubova, J.; Hasani-Sadrabadi, M. M.; Norris, S. C.; Kasko, A. M.; Li, S.
10.1101/2021.02.11.430875 — bioengineering — Posted on 2021-02-15
2227 Metabolic and Process Engineering for Microbial Production of Protocatechuate from Xylose with Corynebacterium glutamicum
Labib, M.; Görtz, J.; Brüsseler, C.; Kallscheuer, N.; Gätgens, J.; Jupke, A.; Marienhagen, J.; Noack, S.
10.1101/2021.02.12.430943 — bioengineering — Posted on 2021-02-15
2231 Structure and mechanistic analyses of the gating mechanism of elongating ketosynthases
Mindrebo, J. T.; Chen, A.; Kim, W. E.; Re, R. N.; Davis, T. D.; Noel, J. P.; Burkart, M. D.
10.1101/2021.02.13.431092 — biochemistry — Posted on 2021-02-14
2235 Structure of an infectious mammalian prion
Kraus, A.; Hoyt, F.; Schwartz, C.; Hansen, B.; Hughson, A. G.; Artikis, E.; Race, B.; Caughey, B.
10.1101/2021.02.14.431014 — biochemistry — Posted on 2021-02-15
2236 Cancer blues? A validated judgment bias task suggests pessimism in nude mice with tumors
Resasco, A.; MacLellan, A.; Ayala, M. A.; Kitchenham, L.; Edwards, M.; Lam, S.; Dejardin, S.; Mason, G.
10.1101/2021.02.13.431089 — animal behavior and cognition — Posted on 2021-02-14
2238 Genomic evidence that governmentally produced Cannabis sativa poorly represents genetic variation available in state markets
Vergara, D.; Huscher, E. L.; Keepers, K. G.; Pisupati, R.; Schwabe, A. L.; McGlaughlin, M. E.; Kane, N. C.
10.1101/2021.02.13.431041 — genomics — Posted on 2021-02-14
2240 A benchmarking of human mitochondrial DNA haplogroup classifiers from whole-genome and whole-exome sequence data
Garcia-Olivares, V.; Munoz-Barrera, A.; Lorenzo-Salazar, J. M.; Zaragoza-Trello, C.; Rubio-Rodriguez, L. A.; Diaz-de Usera, A.; Jaspez-Toledo, D.; Inigo-Campos, A.; Gonzalez-Montelongo, R.; Flores, C.
10.1101/2021.02.11.430775 — genomics — Posted on 2021-02-15
2241 Epigenetic modulation in the pathogenesis and treatment of inherited aortic aneurysm conditions
Kang, B. E.; Bagirzadeh, R.; Bedja, D.; Doyle, J. J.; MacFarlane, E. G.; Dietz, H. C.
10.1101/2021.02.12.431010 — genetics — Posted on 2021-02-14
2243 Antisense oligonucleotide-based drug development for Cystic Fibrosis patients carrying the 3849+10kb C-to-T splicing mutation
Oren, Y. S.; Irony-Tur Sinai, M.; Golec, A.; Barchad-Avitzur, O.; Mutyam, V.; Li, Y.; Hong, J.; Ozeri-Galai, E.; Hatton, A.; Reiter, J.; Sorscher, E. J.; Wilton, S. D.; Kerem, E.; Rowe, S. M.; Sermet-Gaudelus, I.; Kerem, B.
10.1101/2021.02.14.431123 — genetics — Posted on 2021-02-14
2245 Evaluating Sleep Disturbances in Children with Rare Genetic Neurodevelopmental Syndromes
Veatch, O. J.; Malow, B. A.; Lee, H.-S.; Knight, A.; Barrish, J. O.; Neul, J. L.; Lane, J. B.; Skinner, S. A.; Kaufmann, W. E.; Miller, J. L.; Driscoll, D. J.; Bird, L. M.; Butler, M. G.; Dykens, E. M.; Gold, J.-A.; Kimonis, V.; Bacino, C. A.; Tan, W.-H.; Kothare, S. V.; Peters, S. U.; Percy, A. K.; Glaze, D. G.
10.1101/2021.02.12.430633 — genetics — Posted on 2021-02-15
2246 Delineating the molecular and phenotypic spectrum of the SETD1B-related syndrome
Weerts, M. J. A.; Lanko, K.; Guzman-Vega, F. J.; Jackson, A.; Ramakrishnan, R.; Cardona-Londono, K. J.; Pena-Guerra, K. A.; van Bever, Y.; van Paassen, B.; Kievit, A.; van Slegtenhorst, M.; Allen, N. M.; Kehoe, C. M.; Robinson, H. K.; Pang, L.; Banu, S. H.; Zaman, M.; Efthymiou, S.; Houlden, H.; Jarvela, I.; Lauronen, L.; Maatta, T.; Schrauwen, I.; Leal, S. M.; Ruivenkamp, C. A. L.; Barge-Schaapveld, D. Q. C. M.; Peeters-Scholte, C. M. P. C. D.; Galehdari, H.; Mazaheri, N.; Sisodiya, S. M.; Harrison, V.; Sun, A.; Thies, J.; Pedroza, L. A.; Taranchenko, Y. L.; Chinn, I. K.; Lupski, J. R.; Garza
10.1101/2021.02.11.430742 — genetics — Posted on 2021-02-15
2251 The essential role of Dnmt1 in gametogenesis in the large milkweed bug Oncopeltus fasciatus
Washington, J. T.; Cavender, K. R.; Amukamara, A. U.; McKinney, E. C.; Schmitz, R. J.; Moore, P. J.
10.1101/2020.07.23.218180 — evolutionary biology — Posted on 2021-02-15
2252 Climate warming changes synchrony of plants and pollinators
Freimuth, J.; Bossdorf, O.; Scheepens, J. F.; Willems, F. M.
10.1101/2021.01.10.425984 — ecology — Posted on 2021-02-14
2253 Forest loss in Indonesian New Guinea: trends, drivers, and outlook
Gaveau, D.; Santos, L.; Locatelli, B.; Salim, M. A.; Husnayaen, H.; Meijaard, E.; Heatubun, C.; Sheil, D.
10.1101/2021.02.13.431006 — ecology — Posted on 2021-02-14
2254 Tree phylogenetic diversity supports nature's contributions to people, but is at risk from human population growth
Davies, J.; Maurin, O.; Yessoufou, K.; Daru, B.; Bezeng, B.; Schaefer, H.; Thuiller, W.; van der Bank, M.
10.1101/2021.02.13.430985 — ecology — Posted on 2021-02-14
2255 Influence of warming temperatures on coregonine embryogenesis within and among species
Stewart, T. R.; Makinen, M.; Goulon, C.; Guillard, J.; Marjomaki, T. J.; Lasne, E.; Karjalainen, J.; Stockwell, J. D.
10.1101/2021.02.13.431107 — ecology — Posted on 2021-02-14
2260 Nitrate enhances anaerobic oxidation of methane in boreal lake sediments
Rissanen, A. J.; Jilbert, T.; Simojoki, A.; Mangayil, R.; Aalto, S. L.; Peura, S.; Jäntti, H.
10.1101/2021.02.12.426818 — ecology — Posted on 2021-02-15
2261 Paths and Pathways that Generate Cell-Type Heterogeneity and Developmental Progression in Hematopoiesis
Girard, J. R.; Goins, L. M.; Vuu, D. M.; Sharpley, M. S.; Spratford, C. M.; Mantri, S. R.; Banerjee, U.
10.1101/2021.02.11.430681 — developmental biology — Posted on 2021-02-13
2264 Developmental co-emergence of cardiac and gut tissues modeled by human iPSC-derived organoids
Silva, A. C.; Matthys, O. B.; Joy, D. A.; Kauss, M. A.; Natarajan, V.; Lai, M. H.; Turaga, D.; Blair, A. P.; Alexanian, M.; Bruneau, B. G.; McDevitt, T. C.
10.1101/2020.04.30.071472 — developmental biology — Posted on 2021-02-15
2265 GRK2/3/5/6 knockout: The impact of individual GRKs on arrestin-binding and GPCR regulation
Drube, J.; Haider, R. S.; Matthees, E. S. F.; Reichel, M.; Zeiner, J.; Fritzwanker, S.; Ziegler, C.; Barz, S.; Klement, L.; Kliewer, A.; Miess, E.; Kostenis, E.; Schulz, S.; Hoffmann, C.
10.1101/2021.02.12.430971 — cell biology — Posted on 2021-02-13
2266 Atg8 licenses adipokine nuclear exit
Poling, M. E.; Sullivan, C. E.; Brent, A. E.; Hafer, T. L.; Rajan, A.
10.1101/2021.01.29.428913 — cell biology — Posted on 2021-02-13
2267 Ferulic acid combined with skeletal stem cells to repair irradiated bone defect
Liang, W. J.; Li, L. P.; Wang, Q.; Liao, S.; Hu, w.; Zhao, D. Z.; Li, L. Z.; Yin, F. B.; Mao, N.; Ding, L.; Zhu, H.
10.1101/2021.02.14.431131 — cell biology — Posted on 2021-02-14
2269 New multiscale characterisation methodology for effective determination of isolationstructure-function relationship of extracellular vesicles.
Phan, T. H.; Divakarla, K. S.; Yeo, J. H.; Lei, Q.; Tharkar, P.; Pansani, T. N.; Leslie, K. G.; Tong, M.; Coleman, V. A.; Jamting, A.; Plessis, M.-D. D.; New, E. J.; KALIONIS, B.; Demokritou, P.; Woo, H.-K.; Cho, Y.-K.; Chrzanowski, W.
10.1101/2021.02.09.430523 — cell biology — Posted on 2021-02-14
2270 Remodeling and activation mechanisms of outer arm dyneins revealed by cryo-electron microscopy
Kubo, S.; Yang, S. K.; Black, C.; Dai, D.; Valente, M.; Gaertig, J.; Ichikawa, M.; Bui, K. H.
10.1101/2020.11.30.404319 — cell biology — Posted on 2021-02-14
2273 A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes corpus luteum regression
Li, D.; Chen, J.; Guo, J.; Li, L.; Cai, G.; Chen, S.; Huang, J.; Yang, H.; Zhuang, Y.; Wang, F.; Wang, X.
10.1101/2021.02.14.431152 — cell biology — Posted on 2021-02-15
2274 Reaction of ependymal cells to spinal cord injury: a potential role for oncostatin pathway and microglial cells
Chevreau, R.; Ghazale, H.; Ripoll, C.; Chalfouh, C.; Delarue, Q.; Hemonnot, A. L.; Hirbec, H.; Wahane, S.; Perrin, F.; Noristani, H.; Guerout, N.; Hugnot, J.
10.1101/2021.02.12.428106 — cell biology — Posted on 2021-02-15
2276 Reaction of ependymal cells to spinal cord injury: a potential role for oncostatin pathway and microglial cells
Chevreau, R.; Ghazale, H.; Ripoll, C.; Chalfouh, C.; Delarue, Q.; Hemonnot-Girard, A. L.; Hirbec, H.; Wahane, S.; Perrin, F.; Noristani, H.; Guerout, N.; Hugnot, J.
10.1101/2021.02.12.428106 — cell biology — Posted on 2021-02-15
2279 CSF metabolites associate with CSF tau and improve prediction of Alzheimer's disease status
Dong, R.; Darst, B. F.; Deming, Y.; Ma, Y.; Lu, Q.; Zetterberg, H.; Blennow, K.; Carlsson, C. M.; Johnson, S. C.; Asthana, S.; Engelman, C. D.
10.1101/2021.01.31.429054 — molecular biology — Posted on 2021-02-14
2285 Suppression of Plasmodium MIF-CD74 Signaling Protects Against Severe Malaria
Baeza Garcia, A.; Siu, E.; Du, X.; Leng, L.; Franke-Fayard, B.; Janse, C. J.; Howland, S.; Renia, L.; Lolis, E.; Bucala, R.
10.1101/2021.02.14.430970 — microbiology — Posted on 2021-02-14
2286 Genomes of gut bacteria from Nasonia wasps shed light on phylosymbiosis and microbe-assisted hybrid breakdown
Cross, K. L.; Leigh, B. A.; Hatmaker, E. A.; Mikaelyan, A.; Miller, A. K.; Bordenstein, S. R.
10.1101/2021.02.13.431100 — microbiology — Posted on 2021-02-14
2287 Chemical ecology of a tripartite symbiosis
Mucci, N. C.; Jones, K. A.; Cao, M.; Wyatt, M. R.; Foye, S.; Kauffman, S.; Taufer, M.; Chikaraishi, Y.; Steffan, S.; Campagna, S.; Goodrich-Blair, H.
10.1101/2021.02.13.430781 — microbiology — Posted on 2021-02-14
2288 Chemical ecology of a tripartite symbiosis
Mucci, N. C.; Jones, K. A.; Cao, M.; Wyatt, M. R.; Foye, S.; Kauffman, S.; Taufer, M.; Chikaraishi, Y.; Steffan, S.; Campagna, S.; Goodrich-Blair, H.
10.1101/2021.02.13.430781 — microbiology — Posted on 2021-02-15
2290 Fast, efficient and virus-free generation of TRAC-replaced CAR T cells
Kath, J.; Du, W.; Thommandru, B.; Turk, R.; Amini, L.; Stein, M.; Zittel, T.; Martini, S.; Ostendorf, L.; Wilhelm, A.; Akyuez, L.; Rehm, A.; Hoepken, U. E.; Pruss, A.; Kuenkele, A.; Jacobi, A. M.; Volk, H.-D.; Schmueck-Henneresse, M.; Reinke, P.; Wagner, D. L.
10.1101/2021.02.14.431017 — immunology — Posted on 2021-02-14
2291 Meta-analysis of scRNA seq data to define the landscape of human liver immune homeostasis.
Rocque, B. L.; Barbetta, A.; Singh, P.; Goldbeck, C.; Helou, D. G.; Loh, Y.-H. E.; Ung, N.; Lee, J.; Akbari, O.; Emamaullee, J.
10.1101/2021.02.12.430976 — immunology — Posted on 2021-02-14
2292 A single-cell atlas of lymphocyte adaptive immune repertoires and transcriptomes reveals age-related differences in convalescent COVID-19 patients
Bieberich, F.; Vazquez-Lombardi, R.; Yermanos, A.; Ehling, R. A.; Mason, D. M.; Wagner, B.; Kapetanovic, E.; Di Roberto, R. B.; Weber, C. R.; Savic, M.; Rudolf, F.; Reddy, S. T.
10.1101/2021.02.12.430907 — immunology — Posted on 2021-02-15
2295 Cholinergic signalling at the body wall neuromuscular junction couples to distal inhibition of feeding in C. elegans
Izquierdo, P. G.; Thisainathan, T.; Atkins, J. H.; Lewis, C. J.; Tattersall, J. E. H.; Green, A. C.; Holden-Dye, L.; OConnor, V.
10.1101/2021.02.12.430967 — neuroscience — Posted on 2021-02-15
2296 SIPA1L1/SPAR1 is a non-PSD protein involved in GPCR signaling
Matsuura, K.; Kobayashi, S.; Konno, K.; Yamasaki, M.; Horiuchi, T.; Senda, T.; Hayashi, T.; Satoh, K.; Arima-Yoshida, F.; Iwasaki, K.; Negishi, L.; Yasui-Shimizu, N.; Kohu, K.; Kawahara, S.; Kirino, Y.; Nakamura, T.; Watanabe, M.; Yamamoto, T.; Manabe, T.; Akiyama, T.
10.1101/2021.02.12.430872 — neuroscience — Posted on 2021-02-15
2297 Neural indicators of human gut feelings
Mayeli, A.; Al Zoubi, O.; White, E. J.; Chappelle, S.; Kuplicki, R.; Smith, R.; Feinstein, J. S.; Bodurka, J.; Paulus, M. P.; Khalsa, S. S.
10.1101/2021.02.11.430867 — neuroscience — Posted on 2021-02-15
2299 Tracing Human Amygdala across School Age
Zhou, Q.; Liu, S.; Jiang, C.; He, Y.; Zuo, X.-N.
10.1101/2021.02.11.430883 — neuroscience — Posted on 2021-02-15
2302 Genetic influence on resting state networks in young male and female adults
Hwang, G.; Kulkarni, A. P.; Mohanty, R.; Cook, C. J.; Nair, V. A.; Bendlin, B. B.; Meyerand, E.; Prabhakaran, V.
10.1101/2021.02.13.430156 — neuroscience — Posted on 2021-02-15
2306 Systematic beach monitoring as a health assessment tool: cetacean morbillivirus under non-epizootic circumstances in stranded dolphins
Marutani, V. H. B.; Miyabe, F. M.; Alfieri, A. F.; Domit, C.; de Matos, A. M. R. N.; Filho, M. R. C. M.; Bracarense, A. P. F. R. L.
10.1101/2021.02.13.431109 — pathology — Posted on 2021-02-14
2308 Unravelling cotton RNAseq repositories to the fiber development specific modules and their alliance with the fiber-related traits
Prasad, P.; Khatoon, U.; Verma, R. K.; Kumar, A.; Mohapatra, D.; Bhattacharya, P.; Bag, S. K.; Sawant, S. V.
10.1101/2021.02.13.431059 — plant biology — Posted on 2021-02-13
2309 Whole plant-environment microscopy reveals how Bacillus subtilis utilises the soil pore space to colonise plant roots
Liu, Y.; Patko, D.; Engelhardt, I.; George, T. S.; Stanley-Wall, N.; Ladmiral, V.; Ameduri, B.; Daniell, T. J.; Holden, N.; MacDonald, M. P.; Dupuy, L. X.
10.1101/2021.02.13.430456 — plant biology — Posted on 2021-02-13
2310 slim shady is a novel allele of PHYTOCHROMEB present in the T-DNA line SALK_015201
Dash, L.; McEwan, R. E.; Montes, C.; Mejia, L.; Walley, J. W.; Dilkes, B. P.; Kelley, D. R.
10.1101/2021.02.12.430994 — plant biology — Posted on 2021-02-13
2311 Developmental effects on pattern visual evoked potentials characterized by principal component analysis
Patterson Gentile, C.; Joshi, N. R.; Ciuffreda, K.; Arbogast, K.; Master, C.; Aguirre, G.
10.1101/2020.12.11.420158 — neuroscience — Posted on 2021-02-13
2317 Evaluation of high-resolution atmospheric and oceanic simulations of the California Current System
Renault, L.; McWilliams, J. C.; Kessouri, F.; Jousse, A.; Frenzel, H.; Chen, R.; Deutsch, C. A.
10.1101/2020.02.10.942730 — ecology — Posted on 2021-02-13
2318 Biogeochemical variability in the California Current System
Deutsch, C. A.; Frenzel, H.; McWilliams, J. C.; Renault, L.; Kessouri, F.; Howard, E. M.; Liang, J.-H.; Bianchi, D.; Yang, S.
10.1101/2020.02.10.942565 — ecology — Posted on 2021-02-13
2319 A Connectivity-based Psychometric Prediction Framework for Brain-behavior Relationship Studies
Wu, J.; Eickhoff, S. B.; Hoffstaedter, F.; Patil, K. R.; Schwender, H.; Yeo, B. T. T.; Genon, S.
10.1101/2020.01.15.907642 — neuroscience — Posted on 2021-02-13
2320 A specific agonist of the orphan nuclear receptor NR2F1 suppresses metastasis through the induction of cancer cell dormancy
Khalil, B. D.; Sanchez, R.; Rahman, T.; Rodriguez-Tirado, C. A.; Moritsch, S.; Rodriguez Martinez, A.; Miles, B.; Farias, E.; Mezei, M.; Cheung, J. F.; Nobre, A. R.; Kale, N.; Sproll, K. C.; Sosa, M. S.; Aguirre-Ghiso, J. A.
10.1101/2021.01.30.428967 — cancer biology — Posted on 2021-02-13
2325 Tracing production instability in a clonally-derived CHO cell line using single cell transcriptomics
Tzani, I.; Herrmann, N.; Carillo, S.; Spargo, C. A.; Hagan, R.; Barron, N.; Bones, J.; Dillmore, W. S.; Clarke, C.
10.1101/2020.11.04.368480 — cell biology — Posted on 2021-02-13
2326 A Human Multi-Lineage Hepatic Organoid Model for Liver Fibrosis
GUAN, Y.; Enejder, A.; Wang, M.; Fang, Z.; Cui, L.; Chen, S.-Y.; Wang, J.; Tan, Y.; Wu, M.; Chen, X.; Johansson, P. K.; Osman, I.; Kunimoto, K.; Russo, P.; Heilshorn, S. C.; Peltz, G.
10.1101/2020.09.01.278473 — cell biology — Posted on 2021-02-13
2328 Sex-specific lipid profiles in muscle of Atlantic salmon juveniles
House, A. H.; Primmer, C. R.; Debes, P. V.; Erkinaro, J.; Kakela, R.; Kurko, J.
10.1101/2020.11.13.379321 — molecular biology — Posted on 2021-02-13
2330 Methane-derived carbon flow through host-virus trophic networks in soil
Lee, S.; Sieradzki, E. T.; Nicolas, A. M.; Walker, R.; Firestone, M. K.; Hazard, C.; Nicol, G. W.
10.1101/2020.12.16.423115 — microbiology — Posted on 2021-02-13
2331 A non-adaptive demographic mechanism for genome expansion in Streptomyces
Choudoir, M. J.; Järvenpää, M. J.; Marttinen, P.; Buckley, D. H.
10.1101/2021.01.09.426074 — microbiology — Posted on 2021-02-13
2332 Transcriptome signature of cell viability predicts drug response and drug interaction for Tuberculosis
Srinivas, V.; Ruiz, R. A.; Pan, M.; Immanuel, S. R. C.; Peterson, E. J. R.; Baliga, N. S.
10.1101/2021.02.09.430468 — microbiology — Posted on 2021-02-13
2336 Ventral Pallidum GABA Neurons Mediate Motivation Underlying Risky Choice
Farrell, M. R.; Esteban, J.; Faget, L.; Floresco, S. B.; Hnasko, T. S.; Mahler, S. V.
10.1101/2020.08.04.221960 — neuroscience — Posted on 2021-02-13
2338 Adaptation to recent outcomes attenuates the lasting effect of initial experience on risky decisions
Kobor, A.; Kardos, Z.; Takacs, A.; Elteto, N.; Janacsek, K.; Toth-Faber, E.; Csepe, V.; Nemeth, D.
10.1101/2020.09.25.313551 — neuroscience — Posted on 2021-02-13
2339 Automated Analysis of Low-Field Brain MRI in Cerebral Malaria
Tu, D.; Goyal, M. S.; Dworkin, J. D.; Kampondeni, S.; Vidal, L.; Biondo-Savin, E.; Juvvadi, S.; Raghavan, P.; Nicholas, J.; Chetcuti, K.; Clark, K.; Satterthwaite, T. D.; Yushkevich, P.; Davatzikos, C.; Erus, G.; Postels, D. G.; Taylor, T. E.; Small, D. S.; Shinohara, R. T.
10.1101/2020.12.23.424020 — neuroscience — Posted on 2021-02-13
2340 Phenotypic analysis of catastrophic childhood epilepsy genes: The Epilepsy Zebrafish Project
Griffin, A.; Carpenter, C.; Liu, J.; Paterno, R.; Grone, B.; Hamling, K.; Moog, M.; Dinday, M. T.; Figueroa, F.; Anvar, M.; Ononuju, C.; Qu, T.; Baraban, S. C.
10.1101/2021.02.11.430844 — neuroscience — Posted on 2021-02-13
2341 Proton receptors regulate synapse-specific reconsolidation in the amygdala
Koffman, E. E.; Kruse, C. M.; Singh, K.; Naghavi, F. N.; Egbo, J. A.; Boateng, S.; Houdi, M. B.; Lin, B.; Debiec, J.; Du, J.
10.1101/2021.01.04.425235 — neuroscience — Posted on 2021-02-13
2342 Coordination between growth and stress responses by DELLA in the liverwort Marchantia polymorpha
Hernandez-Garcia, J.; Sun, R.; Serrano-Mislata, A.; Inoue, K.; Vargas-Chavez, C.; Esteve-Bruna, D.; Arbona, V.; Yamaoka, S.; Nishihama, R.; Kohchi, T.; Blazquez, M. A.
10.1101/2021.02.11.430820 — plant biology — Posted on 2021-02-13
2343 Dietary restriction in the long-chain acyl-CoA dehydrogenase knockout mouse
Diekman, E.; van Weeghel, M.; Suarez-Farinas, M.; Argmann, C.; Ranea-Robles, P.; Wanders, R.; Visser, G.; van der Made, I.; Creemers, E.; Houten, S.
10.1101/2020.12.03.408591 — physiology — Posted on 2021-02-13
2347 Copy-scAT: Deconvoluting single-cell chromatin accessibility of genetic subclones in cancer
Nikolic, A.; Signal, D.; Ellestad, K.; Johnston, M.; Gillmor, A.; Morrissy, S.; Chan, J. A.; Neri, P.; Bahlis, N.; Gallo, M.
10.1101/2020.09.21.305516 — bioinformatics — Posted on 2021-02-13
2349 Non-invasive sex genotyping of paiche Arapaima gigas by qPCR: An applied bioinformatic approach to identify sex differences
López-Landavery, E. A.; Corona-Herrera, G. A.; Santos-Rojas, L. E.; Herrera-Castillo, N. M.; Delgadin, T. H.; Tapia-Morales, S.; González-Martinez, S.; Reyes-Flores, L. E.; Marín, A.; Yázsiga-Barrera, C. G.; Fernandino, J. I.; Zelada-Mázmela, E.
10.1101/2021.02.12.430980 — genomics — Posted on 2021-02-13
2351 Strong trait correlation and phylogenetic signal in North American ground beetle (Carabidae) morphology
Stachewicz, J. D.; Fountain-Jones, N. M.; Koontz, A.; Woolf, H.; Pearse, W. D.; Gallinat, A. S.
10.1101/2021.02.12.431029 — evolutionary biology — Posted on 2021-02-13
2355 Joint changes in RNA, RNA polymerase II, and promoter activity through the cell cycle identify non-coding RNAs involved in proliferation
Hegre, S. A.; Samdal, H.; Klima, A.; Stovner, E. B.; Norsett, K. G.; Liabakk, N.-B.; Olsen, L. C.; Chawla, K.; Aas, P. A.; Saetrom, P.
10.1101/2021.02.12.430890 — molecular biology — Posted on 2021-02-12
2357 SARS-CoV-2 mutations acquired in mink reduce antibody-mediated neutralization
Hoffmann, M.; Zhang, L.; Krueger, N.; Graichen, L.; Kleine-Weber, H.; Hofmann-Winkler, H.; Kempf, A.; Nessler, S.; Riggert, J.; Winkler, M. S.; Schulz, S.; Jaeck, H.-M.; Poehlmann, S.
10.1101/2021.02.12.430998 — molecular biology — Posted on 2021-02-12
2362 Do size and shape matter? Exploring the interactions and the metabolome of the soil isolate Hylemonella gracilis
Tyc, O.; Kulkarni, P.; Ossowicki, A.; Tracanna, V.; Medema, M.; Baarlen, P. v.; van IJcken, W.; Verhoeven, K. J. F.; Garbeva, P.
10.1101/2021.02.11.430889 — microbiology — Posted on 2021-02-12
2365 Recurrent Vulvovaginal Candidiasis; a dynamic interkingdom biofilm disease of Candida and Lactobacillus
McKloud, E.; Sherry, L.; Kean, R.; Delaney, C.; Williams, S.; Metcalfe, R.; Thomas, R.; Williams, C.; Ramage, G.
10.1101/2021.02.12.430906 — microbiology — Posted on 2021-02-12
2370 Single-cell sequencing of plasma cells from COVID-19 patients reveals highly expanded clonal lineages produce specific and neutralizing antibodies to SARS-CoV-2
Ehling, R. A.; Weber, C. R.; Mason, D. M.; Friedensohn, S.; Wagner, B.; Bieberich, F.; Kapetanovic, E.; Vazquez-Lombardi, R.; Di Roberto, R. B.; Hong, K.-L.; Wagner, C.; Sheward, D. J.; Murrell, B.; Yermanos, A.; Cuny, A.; Savic, M.; Rudolf, F.; Reddy, S. T.
10.1101/2021.02.12.430940 — immunology — Posted on 2021-02-12
2371 Sensitivity of infectious SARS-CoV-2 B.1.1.7 and B.1.351 variants to neutralizing antibodies
Planas, D.; Bruel, T.; Grzelak, L.; Guivel-Benhassine, F.; Staropoli, I.; Porrot, F.; Planchais, C.; Buchrieser, J.; Rajah, M. M.; Bishop, E.; Albert, M.; Donati, F.; Behillil, S.; Enouf, V.; Marianne, M.; Gonzalez, M.; De Seze, J.; Pere, H.; Veyer, D.; Seve, A.; Simon-Loriere, E.; Fafi-Kremer, S.; Stefic, K.; Mouquet, H.; Hocqueloux, L.; van der Werf, S.; Prazuck, T.; Schwartz, O.
10.1101/2021.02.12.430472 — immunology — Posted on 2021-02-12
2372 Elucidating Mechanisms of Antitumor Immunity Mediated by Live Oncolytic Vaccinia and Heat-Inactivated Vaccinia
Wang, W.; Dai, P.; Liu, S.; Yang, N.; Wang, Y.; Giese, R. A.; Merghoub, T.; Wolchok, J. D.; Deng, L.
10.1101/2021.02.11.427912 — immunology — Posted on 2021-02-12
2373 Development and validation of a mouse model of contemporary cannabis smoke exposure
Fantauzzi, M. F.; Cass, S. P.; McGrath, J. J.; Thayaparan, D.; Wang, P.; Stampfli, M. R.; Hirota, J. A.
10.1101/2021.02.11.430865 — immunology — Posted on 2021-02-13
2374 Sterile Inflammation Alters Neutrophil Kinetics in Mice
Singh, A.; Jothiprakasam, T.; Raghavan, J. V.; Jhunjhunwala, S.
10.1101/2021.02.12.430891 — immunology — Posted on 2021-02-13
2377 Interplay between brassinosteroids and TORC signaling in Arabidopsis revealed by integrated multi-dimensional analysis
Montes, C.; Liao, C.-Y.; Nolan, T. M.; Song, G.; Clark, N. M.; Guo, H.; Bassham, D. C.; Yin, Y.; Walley, J.
10.1101/2021.02.12.431003 — plant biology — Posted on 2021-02-13
2378 Benchmarking Association Analyses of Continuous Exposures with RNA-seq in Observational Studies
Sofer, T.; Kurniansyah, N.; Aguet, F.; Ardlie, K.; Durda, P.; Nickerson, D. A.; Smith, J. D.; Liu, Y.; Gharib, S. A.; Redline, S.; Rich, S. S.; Rotter, J. I.; Taylor, K.
10.1101/2021.02.12.430989 — bioinformatics — Posted on 2021-02-13
2379 StrainFLAIR: Strain-level profiling of metagenomic samples using variation graphs
Da Silva, K.; Pons, N.; Berland, M.; Plaza Onate, F.; Almeida, M.; Peterlongo, P.
10.1101/2021.02.12.430979 — bioinformatics — Posted on 2021-02-13
2382 Dopamine modulates visual threat processing in the superior colliculus via D2 receptors
Montardy, Q.; Zhou, Z.; Li, L.; Yang, Q.; Lei, Z.; Feng, X.; Chen, S.; Shi, Q.; Zhang, H.; Chen, S.; Zhang, Z.; Zhao, B.; Xu, F.; Lu, Z.; Wang, L.
10.1101/2021.02.12.430615 — neuroscience — Posted on 2021-02-12
2384 Promiscuous specialists: Host specificity patterns among generalist louse flies
Lehikoinen, A.; Pohjola, P.; Valkama, J.; Mutanen, M.; Pohjoismäki, J. L. O.
10.1101/2021.02.12.430912 — zoology — Posted on 2021-02-12
2387 KCTD19 associates with ZFP541 and HDAC1 and is required for meiotic exit in male mice
Oura, S.; Koyano, T.; Kodera, C.; Horisawa-Takada, Y.; Matsuyama, M.; Ishiguro, K.-i.; Ikawa, M.
10.1101/2021.02.12.430913 — developmental biology — Posted on 2021-02-12
2389 Lack of parent-of-origin effects in Nasonia jewel wasp: a replication and extension study
Olney, K. C.; Gibson, J. D.; Natri, H. M.; Underwood, A.; Gadau, J.; Wilson, M. A.
10.1101/2021.02.11.430138 — genomics — Posted on 2021-02-12
2390 Arboreal aperitifs: Space use and activity of a major songbird nest predator in a tropical Thailand forest
D'souza, A.; Gale, G. A.; Marshall, B. M.; Khamcha, D.; Waengsothorn, S.; Strine, C. T.
10.1101/2021.02.09.430242 — ecology — Posted on 2021-02-12
2391 Relationships between biomechanical parameters, neurological recovery, and neuropathology following concussion in swine
Wofford, K. L.; Grovola, M. R.; Adewole, D. O.; Browne, K. D.; Putt, M. E.; O'Donnell, J. C.; Cullen, D. K.
10.1101/2021.02.09.430268 — neuroscience — Posted on 2021-02-12
2392 Targeting Gys1 with AAV-SaCas9 decreases pathogenic polyglucosan bodies and neuroinflammation in Adult Polyglucosan Body and Lafora disease mouse models
Gumusgoz, E.; Guisso, D. R.; Kasiri, S.; Wu, J.; Dear, M.; Verhalen, B.; Nitschke, S.; Mitra, S.; Nitschke, F.; Minassian, B. A.
10.1101/2021.02.12.430952 — neuroscience — Posted on 2021-02-12
2400 The clinical and functional effects of TERT variants in myelodysplastic syndrome
Reilly, C. R.; Myllymaki, M.; Redd, R.; Padmanaban, S.; Karunakaran, D.; Tesmer, V.; Tsai, F. D.; Gibson, C. J.; Rana, H. Q.; Zhong, L.; Saber, W.; Spellman, S. R.; Hu, Z.-H.; Orr, E. H.; Chen, M. M.; De Vivo, I.; Cutler, C.; Antin, J. H.; Neuberg, D.; Garber, J. E.; Nandakumar, J.; Agarwal, S.; Lindsley, R. C.
10.1101/2021.02.11.430624 — genetics — Posted on 2021-02-12
2402 Schizophrenia-linked protein tSNARE1 regulates endolysosomal trafficking in cortical neurons
Plooster, M.; Farrell, M. S.; Rossi, G.; Won, H.; Gupton, S. L.; Brennwald, P. J.
10.1101/2021.02.09.430442 — neuroscience — Posted on 2021-02-12
2405 Cancer cells induce hepatocytes apoptosis in co-opted colorectal cancer liver metastatic lesions
Rada, M.; Tsamchoe, M.; Kapelanski-Lamoureux, A.; Bloom, J.; Petrillo, S.; Kim, D. H.; Lazaris, A.; Metrakos, P.
10.1101/2021.02.11.429243 — cancer biology — Posted on 2021-02-12
2409 Phenotypic analysis of catastrophic childhood epilepsy genes: The Epilepsy Zebrafish Project
Griffin, A.; Carpenter, C.; Liu, J.; Grone, B.; Hamling, K.; Moog, M.; Dinday, M. T.; Figueroa, F.; Anvar, M.; Ononuju, C.; Qu, T.; Baraban, S. C.
10.1101/2021.02.11.430844 — neuroscience — Posted on 2021-02-12
2412 Musicianship and melodic predictability enhance neural gain in auditory cortex during pitch deviance detection
Quiroga-Martinez, D. R.; Hansen, N. C.; Hojlund, A.; Pearce, M.; Brattico, E.; Holmes, E.; Friston, K.; Vuust, P.
10.1101/2021.02.11.430838 — neuroscience — Posted on 2021-02-12
2413 Multi-channel 4D parametrized Atlas of Macro- and Microstructural Neonatal Brain Development
Uus, A.; Grigorescu, I.; Pietsch, M.; Batalle, D.; Christiaens, D.; Hughes, E.; Hutter, J.; Cordero Grande, L.; Price, A. N.; Tournier, J.-D.; Rutherford, M. A.; Counsell, S. J.; Hajnal, J. V.; Edwards, A. D.; Deprez, M.
10.1101/2021.02.11.430835 — neuroscience — Posted on 2021-02-12
2414 Photoperiod shapes aluminium tolerance in plants
Siqueira, J. A.; Wakin, T.; Batista-Silva, W.; Silva, J. C. F.; Vicente, M. H.; Silva, J. C.; Clarindo, W. R.; Zsogon, A.; Peres, L.; De Veylder, L.; Fernie, A. R.; Nunes-Nesi, A.; Araujo, W. L.
10.1101/2021.02.12.430934 — plant biology — Posted on 2021-02-12
2419 The making of cauliflowers: the story of unsuccessful flowers
Azpeitia, E.; Tichtinsky, G.; Le Masson, M.; Serrano-Mislata, A.; Gregis, V.; Gimenez, C.; Prunet, N.; Lucas, J.; Farcot, E.; Kater, M.; Bradley, D.; Madueno, F.; Godin, C.; Parcy, F.
10.1101/2021.02.12.427428 — plant biology — Posted on 2021-02-12
2420 Extensive N4 cytosine methylation is essential for Marchantia sperm function
Walker, J.; Zhang, J.; Liu, Y.; Vickers, M.; Dolan, L.; Nakajima, K.; Feng, X.
10.1101/2021.02.12.428880 — developmental biology — Posted on 2021-02-12
2422 Extensive introgression among North American wild grapes (Vitis) fuels biotic and abiotic adaptation
Morales-Cruz, A.; Aguirre-Liguori, J.; Zhou, Y.; Minio, A.; Riaz, S.; Walker, A. M.; Cantu, D.; Gaut, B. S.
10.1101/2021.02.11.430822 — evolutionary biology — Posted on 2021-02-12
2425 Development of an exosomal biomarker signature to detect minimal residual disease in dogs with osteosarcoma using a novel xenograft platform and machine learning
Makielski, K.; Donnelly, A. J.; Khammanivong, A.; Scott, M. C.; Ortiz, A. R.; Galvan, D. C.; Tomiyasu, H.; Amaya, C.; Ward, K.; Montoya, A.; Garbe, J. R.; Mills, L. J.; Cutter, G. R.; Fenger, J. M.; Kisseberth, W. C.; O'Brien, T. D.; Spector, L. G.; Bryan, B. A.; Subramanian, S.; Modiano, J. F.
10.1101/2021.02.11.429432 — cancer biology — Posted on 2021-02-12
2426 Local thermodynamics governs the formation and dissolution of protein condensates in living cells
Fritsch, A. W.; Diaz-Delgadillo, A. F.; Adame-Arana, O.; Hoege, C.; Kreysing, M.; Mittasch, M.; Leaver, M.; Hyman, A. A.; Julicher, F.; Weber, C. A.
10.1101/2021.02.11.430794 — biophysics — Posted on 2021-02-12
2428 Nse5/6 is a negative regulator of the ATPase activity of the Smc5/6 complex
Hallett, S. T.; Schellenberger, P.; Zhou, L.; Beuron, F.; Morris, E.; Murray, J. M.; Oliver, A.
10.1101/2021.02.12.430902 — biochemistry — Posted on 2021-02-12
2429 Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry
Lei, X.; Wei, T.; Wang, J.; Liang, R.; Chen, W.; He, A.; Du, Y.; Zhou, W.; Zhang, Z.; Ma, M.; Lu, J.; Guo, X.; Chen, X.; Tian, R.; Xiao, J.
10.1101/2021.02.12.430909 — biochemistry — Posted on 2021-02-12
2431 Dynamics and modulation of the human snoRNome
Fafard-Couture, E.; Bergeron, D.; Couture, S.; Abou Elela, S.; Scott, M. S.
10.1101/2021.02.11.430834 — genomics — Posted on 2021-02-12
2433 Post mortem validation of DSI compressed sensing with optical imaging
Jones, R.; Maffei, C.; Augustinack, J.; Fischl, B.; Wang, H.; Bilgic, B.; Yendiki, A.
10.1101/2021.02.11.430672 — neuroscience — Posted on 2021-02-12
2434 Lack of effect of different pain-related manipulations on opioid self-administration, reinstatement of opioid seeking, and opioid choice in rats
Reiner, D. J.; Townsend, E. A.; Menendez, J. O.; Applebey, S. V.; Claypool, S. M.; Banks, M. J.; Shaham, Y.; Negus, S. S.
10.1101/2021.02.11.430808 — neuroscience — Posted on 2021-02-12
2435 Physical phenotype of blood cells is altered in COVID-19
Kubankova, M.; Hohberger, B.; Hoffmanns, J.; Fuerst, J.; Hermann, M.; Guck, J.; Krater, M.
10.1101/2021.02.12.429482 — biophysics — Posted on 2021-02-12
2438 Evidence for Multiple Teosinte Hybrid Zones in Central Mexico
Hufnagel, D. E.; Kananen, K.; Glaubitz, J. C.; Sanchez-Gonzalez, J. d. J.; Doebley, J. F.; Hufford, M. B.
10.1101/2021.02.11.430632 — evolutionary biology — Posted on 2021-02-12
2440 In vitro evolution of Remdesivir resistance reveals genome plasticity of SARS-CoV-2
Szemiel, A. M.; Merits, A.; Orton, R. J.; MacLean, O.; Wickenhagen, A.; Lieber, G.; Pinto, R. M.; Turnbull, M. L.; Wang, S.; Mair, D.; da Silva Filipe, A.; Willett, B. J.; Wilson, S. J.; Patel, A. H.; Thomson, E. C.; Palmarini, M.; Kohl, A.; Stewart, M. E.
10.1101/2021.02.01.429199 — microbiology — Posted on 2021-02-12
2441 Surface-aerosol stability and pathogenicity of diverse MERS-CoV strains from 2012 - 2018
van Doremalen, N.; Letko, M. C.; Fischer, R.; Bushmaker, T.; Yinda, K. C.; Schulz, J.; Seifert, S. N.; Kim, N. J.; Hemida, M. G.; Kayali, G.; Park, W. B.; Perera, R.; Tamin, A.; Thornburg, N. J.; Tong, S.; Queen, K.; Van Kerkhove, M. D.; Choi, Y. K.; Oh, M.-d.; Assiri, A. M.; Peiris, J. S. M.; Gerber, S.; Munster, V.
10.1101/2021.02.11.429193 — microbiology — Posted on 2021-02-12
2442 A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection
Liu, H.; Yuan, M.; Huang, D.; Bangaru, S.; Lee, C.-C. D.; Peng, L.; Zhu, X.; Nemazee, D.; van Gils, M. J.; Sanders, R. W.; Kornau, H.-C.; Reincke, S. M.; Pruss, H.; Kreye, J.; Wu, N. C.; Ward, A. B.; Wilson, I. A.
10.1101/2021.02.11.430866 — microbiology — Posted on 2021-02-12
2444 A single-cell atlas of lymphocyte adaptive immune repertoires and transcriptomes reveals age-related differences in convalescent COVID-19 patients
Bieberich, F.; Vazquez-Lombardi, R.; Yermanos, A.; Ehling, R. A.; Wagner, B.; Kapetanovic, E.; Di Roberto, R. B.; Savic, M.; Rudolf, F.; Reddy, S. T.
10.1101/2021.02.12.430907 — immunology — Posted on 2021-02-12
2446 Discovery of a Novel Inhibitor of Coronavirus 3CL Protease as a Clinical Candidate for the Potential Treatment of COVID-19
Boras, B.; Jones, R. M.; Anson, B. J.; Arenson, D.; Aschenbrenner, L.; Bakowski, M. A.; Beutler, N.; Binder, J.; Chen, E.; Eng, H.; Hammond, J.; Hoffman, R.; Kadar, E. P.; Kania, R.; Kimoto, E.; Kirkpatrick, M. G.; Lanyon, L.; Lendy, E. K.; Lillis, J. R.; Luthra, S. A.; Ma, C.; Noell, S.; Obach, R. S.; O'Brien, M. N.; O'Connor, R.; Ogilvie, K.; Owen, D.; Pettersson, M.; Reese, M. R.; Rogers, T.; Rossulek, M. I.; Sathish, J. G.; Steppan, C.; Ticehurst, M.; Updyke, L. W.; Zhu, Y.; Wang, J.; Chatterjee, A. K.; Mesecar, A. D.; Anderson, A. S.; Allerton, C.; Frieman, M.; Weston, S.; McGrath, M. E.;
10.1101/2020.09.12.293498 — pharmacology and toxicology — Posted on 2021-02-12
2448 The COVID-19 PHARMACOME: A method for the rational selection of drug repurposing candidates from multimodal knowledge harmonization
Schultz, B. T.; Zaliani, A.; Ebeling, C.; Reinshagen, J.; Bojkova, D.; Lage-Rupprecht, V.; Karki, R.; Lukassen, S.; Gadiya, Y.; Ravindra, N. G.; Das, S.; Baksi, S.; Domingo-Fernandez, D.; Lentzen, M.; Strivens, M.; Raschka, T.; Cinatl, J.; DeLong, L. N.; Gribbon, P.; Geisslinger, G.; Ciesek, S.; van Dijk, D.; Gardner, S.; Tom Kodamullil, A.; Froehlich, H.; Peitsch, M.; Jacobs, M.; Hoeng, J.; Eils, R.; Claussen, C.; Hofmann-Apitius, M.
10.1101/2020.09.23.308239 — bioinformatics — Posted on 2021-02-12
2449 NIAGADS Alzheimer's GenomicsDB: A resource for exploring Alzheimer's Disease genetic and genomic knowledge
Greenfest-Allen, E.; Klamann, C.; Gangadharan, P.; Kuzma, A.; Leung, Y. Y.; Valladares, O.; Schellenberg, G.; Stoeckert, C. J.; Wang, L.-S.
10.1101/2020.09.23.310276 — bioinformatics — Posted on 2021-02-12
2450 Joint inference of species histories and gene flow
Mueller, N. F.; Ogilvie, H.; Zhang, C.; Fontaine, M. C.; Amaya-Romero, J. E.; Drummond, A.; Stadler, T.
10.1101/348391 — evolutionary biology — Posted on 2021-02-12
2453 Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7
Wang, P.; Nair, M. S.; Liu, L.; Iketani, S.; Luo, Y.; Guo, Y.; Wang, M.; Yu, J.; Zhang, B.; Kwong, P. D.; Graham, B. S.; Mascola, J. R.; Chang, J. Y.; Yin, M. T.; Sobieszczyk, M. E.; Kyratsous, C. A.; Shapiro, L.; Sheng, Z.; Huang, Y.; Ho, D. D.
10.1101/2021.01.25.428137 — immunology — Posted on 2021-02-12
2455 siRNA enrichment in Argonaute 2-depleted Blattella germanica
Montanes, J. C.; Rojano, C.; Ylla, G.; Piulachs, M.-D.; Maestro, J. L.
10.1101/2021.02.11.430758 — physiology — Posted on 2021-02-12
2457 Ribovore: ribosomal RNA sequence analysis for GenBank submissions and database curation
Schäffer, A. A.; McVeigh, R.; Robbertse, B.; Schoch, C. L.; Johnston, A.; Underwood, B. A.; Karsch-Mizrachi, I.; Nawrocki, E. P.
10.1101/2021.02.11.430762 — bioinformatics — Posted on 2021-02-12
2458 A benchmarking of human mitochondrial DNA haplogroup classifiers from whole-genome and whole-exome sequence data
Garcia-Olivares, V.; Munoz-Barrera, A.; Lorenzo-Salazar, J. M.; Zaragoza-Trello, C.; Rubio-Rodriguez, L. A.; Diaz-de Usera, A.; Jaspez-Toledo, D.; Inigo-Campos, A.; Gonzalez-Montelongo, R.; Flores, C.
10.1101/2021.02.11.430775 — genomics — Posted on 2021-02-12
2460 Identification of a rapidly-spreading triple mutant for high-level metabolic insecticide resistance in Anopheles gambiae provides a real-time molecular diagnostic for anti-malarial intervention deployment.
Njoroge, H.; van't Hof, A.; Oruni, A.; Pipini, D.; Nagi, S. C.; Lynd, A.; Lucas, E. R.; Tomlinson, S.; Grau-Bove, X.; McDermott, D.; Wat'senga, F. t.; Manzambi, E. Z.; Agossa, F. R.; Mokuba, A.; Kabula, B.; Mbogo, C.; Bargul, J.; Paine, M. J.; Weetman, D.; Donnelly, M. J.
10.1101/2021.02.11.429702 — evolutionary biology — Posted on 2021-02-12
2461 Genetic determinants facilitating the evolution of resistance to carbapenem antibiotics
Hung, D.; Ma, P.; He, L. L.; Pironti, A.; Laibinis, H. H.; Ernst, C. M.; Manson, A. L.; Bhattacharyya, R. P.; Earl, A.; Livny, J.
10.1101/2021.02.11.430761 — evolutionary biology — Posted on 2021-02-12
2463 REAP: A platform to identify autoantibodies that target the human exoproteome
Wang, E. Y.; Dai, Y.; Rosen, C. E.; Schmitt, M. M.; Dong, M. X.; Ferre, E. M. N.; Liu, F.; Yang, Y.; Gonzalez-Hernandez, J. A.; Meffre, E.; Hinchcliffe, M.; Koumpouras, F.; Lionakis, M. S.; Ring, A. M.
10.1101/2021.02.11.430703 — immunology — Posted on 2021-02-12
2466 Disordered information processing dynamics in experimental epilepsy
Clawson, W.; Madec, T.; Ghestem, A.; Quilichini, P. P.; Battaglia, D.; Bernard, C.
10.1101/2021.02.11.430768 — neuroscience — Posted on 2021-02-12
2467 Evolutionary divergence of locomotion in two related vertebrate species
Rajan, G.; Lafaye, J.; Carbo-Tano, M.; Duroure, K.; Faini, G.; Tanese, D.; Panier, T.; Candelier, R.; Henninger, J.; Britz, R.; Judkewitz, B.; Gebhardt, C.; Emiliani, V.; Debregeas, G.; Wyart, C.; Del Bene, F.
10.1101/2021.02.11.430752 — neuroscience — Posted on 2021-02-12
2468 Predicting behavior from eye movement and whisking asymmetry
Bergmann, R.; Sehara, K.; Dominiak, S.; Kremkow, J.; Larkum, M.; Sachdev, R.
10.1101/2021.02.11.430785 — neuroscience — Posted on 2021-02-12
2473 Comparative Chromatin Dynamics of Stem Cell Differentiation in Human and Rat
Thai, C. W.; Jiang, S.; Roxas, Y.; McGill, C.; Ma, S.; Mortazavi, A.
10.1101/2021.02.11.430819 — genomics — Posted on 2021-02-12
2475 Polygenic Prediction of Type 2 Diabetes in Continental Africa
Chikowore, T.; Ekoru, K.; Vujkovic, M.; Gill, D.; Pirie, F.; Young, E.; Sandhu, M.; McCarthy, M.; Rotimi, C.; Adeyemo, A.; Motola, A.; Fatumo, S.
10.1101/2021.02.11.430719 — genetics — Posted on 2021-02-12
2476 With great power comes great responsibility: an analysis of sustainable forest management quantitative indicators in the DPSIR framework
Paillet, Y.; Campagnaro, T.; Burrascano, S.; Gosselin, M.; Ballweg, J.; Chianucci, F.; Dorioz, J.; Marsaud, J.; Maciejewski, L.; Sitzia, T.; Vacchiano, G.
10.1101/2021.02.11.430737 — ecology — Posted on 2021-02-12
2480 A compact spatial map in V2 visual cortex
Long, X.; Deng, B.; Cai, J.; Chen, Z. S.; Zhang, S.-J.
10.1101/2021.02.11.430687 — neuroscience — Posted on 2021-02-12
2482 Interdependent Iron and Phosphorus Availability Controls Photosynthesis Through Retrograde Signaling
Nam, H.-I.; Shahzad, Z.; Dorone, Y.; Clowez, S.; Zhao, K.; Bouain, N.; Cho, H.; Rhee, S. Y.; Rouached, H.
10.1101/2021.02.11.430802 — plant biology — Posted on 2021-02-12
2483 Coordination between growth and stress responses by DELLA in the liverwort Marchantia polymorpha
Hernandez-Garcia, J.; Sun, R.; Serrano-Mislata, A.; Inoue, K.; Vargas-Chavez, C.; Esteve-Bruna, D.; Arbona, V.; Yamaoka, S.; Nishihama, R.; Kohchi, T.; Blazquez, M. A.
10.1101/2021.02.11.430820 — plant biology — Posted on 2021-02-12
2488 A robust method of nuclei isolation for single-cell RNA sequencing of solid tissues from the plant genus Populus
Conde, D.; Triozzi, P. M.; Balmant, K. M.; Doty, A. L.; Miranda, M.; Boullosa, A.; Schmidt, H. W.; Pereira, W. J.; Dervinis, C.; Kirst, M.
10.1101/2021.02.11.430521 — plant biology — Posted on 2021-02-12
2490 Integrated plasma proteomic and single-cell immune signaling network signatures demarcate mild, moderate, and severe COVID-19
Feyaerts, D.; Hedou, J.; Gillard, J.; Chen, H.; Tsai, E. S.; Peterson, L. S.; Ando, K.; Manohar, M.; Do, E.; Dhondalay, G. K. R.; Fitzpatrick, J.; Artandi, M.; Chang, I.; Snow, T. T.; Chinthrajah, R. S.; Warren, C. M.; Wittman, R.; Meyerowitz, J. G.; Ganio, E. A.; Stelzer, I. A.; Han, X.; Verdonk, F.; Gaudilliere, D. K.; Mukherjee, N.; Tsai, A. S.; Rumer, K. K.; Jiang, S. J.; Valdes-Ferrer, S. I.; Kelly, J. D.; Furman, D.; Aghaeepour, N.; Angst, M. S.; Boyd, S. D.; Pinsky, B. A.; Nolan, G. P.; Nadeau, K. C.; Gaudilliere, B.; McIlwain, D. R.
10.1101/2021.02.09.430269 — immunology — Posted on 2021-02-12
2491 Dual mTORC1/mTORC2 inhibition as a Host-Directed Therapeutic Target in Pathologically Distinct Mouse Models of Tuberculosis
Tasneen, R.; Mortensen, D. S.; Converse, P. J.; Urbanowski, M. E.; Upton, A.; Fotouhi, N.; Nuermberger, E.; Hawryluk, N.
10.1101/2021.02.10.430715 — pathology — Posted on 2021-02-12
2493 Brain deletion of Serf2 shifts amyloid conformation in a mouse model
Stroo, E.; Janssen, L.; Sin, O.; Hogewerf, W.; Koster, M. H.; Harkema, L.; Youssef, S. A.; beschorner, N.; Wolters, A. H. G.; Bakker, B.; Thathiah, A.; Foijer, F.; van de Sluis, B.; van Deursen, J.; Jucker, M.; de Bruin, A.; Nollen, E.
10.1101/2021.01.05.423442 — molecular biology — Posted on 2021-02-12
2494 The Landscape of Precision Cancer Combination Therapy: A Single-Cell Perspective
Ahmadi, S.; Sukprasert, P.; Vegesna, R.; Sinha, S.; Schischlik, F.; Artzi, N.; Khuller, S.; Schaffer, A. A.; Ruppin, E.
10.1101/2020.01.28.923532 — bioinformatics — Posted on 2021-02-12
2495 Molecular basis for gating and regulation of cardiac ryanodine receptor: underlying mechanisms for gain- and loss-of function mutations
Kobayashi, T.; Tsutsumi, A.; Kurebayashi, N.; Saito, K.; Kodama, M.; Sakurai, T.; Kikkawa, M.; Murayama, T.; Ogawa, H.
10.1101/2020.11.30.401026 — biochemistry — Posted on 2021-02-12
2497 Arabidopsis inositol polyphosphate kinases regulate COP9 signalosome functions in phosphate-homeostasis
Walia, Y.; Kasera, M.; Ingole, K. D.; Peddiraju, S.; Roy, A.; Laha, D.; Schaaf, G.; BHATTACHARJEE, S.
10.1101/2020.10.02.323584 — plant biology — Posted on 2021-02-12
2499 Maternal Biological Age Assessed in Early Pregnancy is Associated with Gestational Age at Birth
Lancaster, E. E.; Lapato, D. M.; Jackson-Cook, C.; Strauss, J. F.; Roberson-Nay, R.; York, T. P.
10.1101/2021.01.11.425979 — genomics — Posted on 2021-02-11
2500 Comprehensive phenotypic analysis of the Dp1Tyb mouse strain reveals a broad range of Down Syndrome-related phenotypes
Lana-Elola, E.; Cater, H.; Watson-Scales, S.; Greenaway, S.; Mueller-Winkler, J.; Gibbins, D.; Nemes, M.; Slender, A.; Hough, T.; Keskivali-Bond, P.; Scudamore, C. L.; Herbert, E.; Banks, G. T.; Mobbs, H.; Canonica, T.; Tosh, J.; Noy, S.; Llorian, M.; Nolan, P. M.; Griffin, J. L.; Good, M.; Simon, M.; Mallon, A.-M.; Wells, S.; Fisher, E. M.; Tybulewicz, V. L.
10.1101/2021.02.11.430828 — genetics — Posted on 2021-02-11
2501 Otolith-based discrimination of cod ecotypes and the effect of growth rate.
Jonsson, E. P.; Jonsson, E. P.; Campana, S. E.; Solmundsson, J.; Jakobsdottir, K. B.; Bartharson, H.
10.1101/2021.02.11.430748 — ecology — Posted on 2021-02-11
2504 Retrospective Study on the Health Problems of Falcons in Al Ain, United Arab Emirates
ameni, G.; Al Hemeiri, M. A.; Arias de la Torre, A.; Mohteshamuddin, K.; Degafa, B. A.
10.1101/2021.02.11.430749 — pathology — Posted on 2021-02-11
2505 Comparative evaluation of full-length isoform quantification from RNA-Seq
Sarantopoulou, D.; Brooks, T. G.; Nayak, S.; Mrcela, A.; Lahens, N. F.; Grant, G. R. R.
10.1101/698605 — bioinformatics — Posted on 2021-02-11
2507 Nigro-striatal dopamine activation lowers behavioral and neuronal phenotypes associated with obsessive-compulsive disorder
Casado-Sainz, A.; Gudmundsen, F.; Baerentzen, S. L.; Lange, D.; Ringsted, A.; Martinez-Tajada, I.; Medina, S.; Lee, H.; Svarer, C.; Keller, S. H.; Schain, M.; Kjaerby, C.; Fisher, P. M.; Cumming, P.; Palner, M.
10.1101/2021.02.11.430770 — neuroscience — Posted on 2021-02-11
2509 The structure of the human cell cycle
Stallaert, W.; Kedziora, K. M.; Taylor, C. D.; Zikry, T. M.; Sobon, H. K.; Taylor, S. R.; Young, C. L.; Limas, J. C.; Cook, J. G.; Purvis, J. E.
10.1101/2021.02.11.430845 — cell biology — Posted on 2021-02-11
2510 Macropinosomes host TLR9 signaling and regulation of inflammatory responses in microglia
Stow, J. L.; Hung, Y.; Tuladhar, N.; Xiao, Z.-J.; Tong, S. J.; Vukovic, J.; Luo, L.; Wall, A. A.
10.1101/2021.02.11.430773 — cell biology — Posted on 2021-02-11
2512 Host-pathogen genetic interactions underlie tuberculosis susceptibility
Smith, C. M.; Baker, R. E.; Proulx, M. K.; Mishra, B. B.; Long, J. E.; Park, S. W.; Lee, H.-N.; Kiritsy, M. C.; Bellerose, M. M.; Olive, A. J.; Murphy, K. C.; Papavinasasundaram, K.; Boehm, F. J.; Reames, C. J.; Meade, R. K.; Hampton, B. K.; Linnertz, C. L.; Ehrt, S.; Schnappinger, D.; Pardo-Manuel de Villena, F.; Ferris, M. T.; Ioerger, T. R.; Sassetti, C. M.
10.1101/2020.12.01.405514 — microbiology — Posted on 2021-02-11
2513 Red Blood Cells Function as DNA Sensors
Lam, M.; Murphy, S.; Kokkinaki, D.; Venosa, A.; Sherrill-Mix, S.; Casu, C.; Rivella, S.; Weiner, A.; Park, J.; Shin, S.; Vaughan, A. E.; Hahn, B. H.; Odom John, A. R.; Meyer, N. J.; Hunter, C. A.; Worthen, G. S.; Mangalmurti, N. S.
10.1101/2021.02.11.430782 — immunology — Posted on 2021-02-11
2514 Immune deposit and vasculopathy in metabolic-active lung tissues of patients with pulmonary tuberculosis
Ma, H.; Wang, L.; Wen, Z.-L.; Chen, X.; Liu, H.; Zhang, S.; Xu, J.; Song, Y.-Z.; Wong, K.-W.
10.1101/2021.02.09.430558 — immunology — Posted on 2021-02-11
2515 Regulation of Human Neutrophil Responses to Candida albicans by Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1), CEACAM3 and CEACAM6
Klaile, E.; Prada Salcedo, J. P.; Klassert, T. E.; Besemer, M.; Bothe, A.-K.; Durotin, A.; Mueller, M. M.; Verena, V.; Luther, C.; Dittrich, M.; Singer, B. B.; Dandekar, T.; Slevogt, H.
10.1101/2021.02.11.430790 — immunology — Posted on 2021-02-11
2517 Quantitative dialing of gene expression via precision targeting of KRAB repressor
Wilken, M. S.; Ciarlo, C.; Pearl, J.; Bloom, J.; Schanzer, E.; Liao, H.; Van Biber, B.; Queitsch, K.; Federation, A.; Acosta, R.; Vong, S.; Otterman, E.; Dunn, D.; Wang, H.; Zrazhevskey, P.; Nandakumar, V.; Bates, D.; Sandstrom, R.; Urnov, F. D.; Funnell, A.; Green, S.; Stamatoyannopoulos, J. A.
10.1101/2020.02.19.956730 — synthetic biology — Posted on 2021-02-11
2518 Root-to-shoot iron partitioning in Arabidopsis requires IRON-REGULATED TRANSPORTER1 (IRT1)
Quintana, J.; Bernal, M. I.; Scholle, M.; Holländer-Czytko, H.; Nga, N.; Piotrowski, M.; Mendoza-Cozatl, D.; Haydon, M. J.; Kraemer, U.
10.1101/2021.02.08.430285 — plant biology — Posted on 2021-02-11
2520 Mitogen-activated protein kinase activity drives cell trajectories in colorectal cancer
Uhlitz, F.; Bischoff, P.; Peidli, S.; Sieber, A.; Obermayer, B.; Blanc, E.; Trinks, A.; Luethen, M.; Ruchiy, Y.; Sell, T.; Mamlouk, S.; Arsie, R.; Wei, T.-T.; Klotz-Noack, K.; Schwarz, R.; Sawitzki, B.; Kamphues, C.; Beule, D.; Landthaler, M.; Sers, C.; Horst, D.; Bluthgen, N.; Morkel, M.
10.1101/2020.01.10.901579 — cancer biology — Posted on 2021-02-11
2521 Identification of CRYAB+ KCNN3+ SOX9+ astro-like and EGFR+ PDGFRA+ OLIG1+ oligo-like tumoral cells in diffuse low-grade gliomas and implication of Notch1 signalling in their genesis
Augustus, M.; Pineau, D.; Aimond, F.; Azar, S.; Lecca, D.; Leventoux, N.; Scamps, F.; Muxel, S.; Darlix, A.; Ritchie, W.; Goze, C.; Rigau, V.; Duffau, H.; Hugnot, J.-P.
10.1101/2021.02.09.430313 — cancer biology — Posted on 2021-02-11
2522 Actin crosslinker competition and sorting drive emergent GUV size-dependent actin network architecture
Bashirzadeh, Y.; Redford, S. A.; Lorpaiboon, C.; Groaz, A.; Litschel, T.; Schwille, P.; Hocky, G. M.; Dinner, A.; Liu, A. P.
10.1101/2020.10.03.322354 — biophysics — Posted on 2021-02-11
2524 Deep learning classification of temporal data in ecology
Capinha, C.; Ceia-Hasse, A.; Kramer, A. M.; Meijer, C.
10.1101/2020.09.14.296251 — ecology — Posted on 2021-02-11
2529 Small intestine lactobacilli growth promotion and immunomodulation in weaner pigs fed Cyberlindnera jadinii yeast high inclusion diet and exposed to enterotoxigenic Escherichia coli F4+: O149
Iakhno, S.; Hellestveit, S. S.; Umu, O. C. O.; Bogevik, L. T.; Akesson, C. P.; Göksu, A. B.; Press, C. M.; Mydland, L. T.; Overland, M.; Sorum, H.
10.1101/2021.02.11.430732 — microbiology — Posted on 2021-02-11
2530 Murine ex vivo cultured alveolar macrophages provide a novel tool to study tissue-resident macrophage behavior and function
Gorki, A.-D.; Symmank, D.; Zahalka, S.; Lakovits, K.; Hladik, A.; Langer, B.; Maurer, B.; Sexl, V.; Kain, R.; Knapp, S.
10.1101/2021.02.11.430791 — immunology — Posted on 2021-02-11
2531 In vivo optogenetic stimulation of the primate retina activates the visual cortex after long-term transduction
Chaffiol, A.; Provansal, M.; Joffrois, C.; Blaize, K.; Labernede, G.; Goulet, R.; Burban, E.; Brazhnikova, E.; Duebel, J.; Pouget, P.; Sahel, J.-A.; Picaud, S.; Gauvain, G.; Arcizet, F.
10.1101/2021.02.09.427243 — neuroscience — Posted on 2021-02-11
2532 Two opposite voltage-dependent currents control the unusual early development pattern of embryonic Renshaw cell electrical activity
Boeri, J.; Meunier, C.; Le Corronc, H.; Branchereau, P.; Timofeeva, Y.; Lejeune, F.-X.; Mouffle, C.; Arulkandarajah, H.; Mangin, J. M.; Legendre, P.; Czarnecki, A.
10.1101/2020.06.18.158931 — neuroscience — Posted on 2021-02-11
2534 Predictive olfactory learning in Drosophila
Zhao, C.; Widmer, Y. F.; Diegelmann, S.; Petrovici, M. A.; Sprecher, S. G.; Senn, W.
10.1101/2019.12.29.890533 — neuroscience — Posted on 2021-02-11
2536 A burden-free gene overexpression system
Barajas, C.; Gibson, J.; Sandoval, L.; del vecchio, d.
10.1101/2021.02.11.430724 — synthetic biology — Posted on 2021-02-11
2538 Constitutively enhanced genome integrity maintenance and direct stress mitigation characterize transcriptome of extreme stress-adapted Arabidopsis halleri
Lee, G.; Ahmadi, H.; Quintana, J.; Syllwasschy, L.; Janina, N.; Preite, V.; Anderson, J. E.; Pietzenuk, B.; Kraemer, U.
10.1101/859249 — plant biology — Posted on 2021-02-11
2539 Effect of using a physical assistance device for movements involving trunk bending
Jelti, Z.; Lebel, K.; Bastide, S.; Le Borgne, P.; Slangen, P.; Vignais, N.
10.1101/2021.02.08.429597 — physiology — Posted on 2021-02-11
2540 Dietary restriction in the long-chain acyl-CoA dehydrogenase knockout mouse
Diekman, E.; van Weeghel, M.; Suarez-Farinas, M.; Argmann, C.; Wanders, R.; Visser, G.; van der Made, I.; Creemers, E.; Houten, S.
10.1101/2020.12.03.408591 — physiology — Posted on 2021-02-11
2541 Immune landscape of a genetically-engineered murine model of glioma relative to human glioma by single-cell sequencing
Zamler, D. B.; Shingu, T.; Kahn, L. M.; Kassab, C.; Ott, M.; Tomczak, K.; Liu, J.; Li, Y.; Lai, I. P.; Yee, C.; Rai, K.; Heimberger, A. B.; Draetta, G.; Hu, J.
10.1101/2020.05.11.088708 — cancer biology — Posted on 2021-02-11
2542 Cytidine triphosphate promotes efficient ParB-dependent DNA condensation by facilitating one-dimensional spreading from parS
Balaguer, F. d. A.; Aicart-Ramos, C.; Fisher, G. L.; de Braganca, S.; Pastrana, C. L.; Dillingham, M. S.; Moreno-Herrero, F.
10.1101/2021.02.11.430778 — biophysics — Posted on 2021-02-11
2543 Effect of ligand sensing on flagellar bundle formation in bacteria
Agrawal, M.; Chakraborty, S.; Tirumkudulu, M. S.; Venkatesh, K. V.
10.1101/2021.02.11.430483 — biophysics — Posted on 2021-02-11
2545 cytoNet: Spatiotemporal Network Analysis of Cell Communities
Mahadevan, A. S.; Long, B. L.; Hu, C. W.; Ryan, D. T.; Grandel, N. E.; Maloney, Z.; Britton, G. L.; Gonzalez Porras, M. A.; Stojkova, K.; Ligeralde, A.; Son, H.; Shannonhouse, J.; Robinson, J. T.; Warmflash, A.; Brey, E.; Kim, Y. S.; Qutub, A. A.
10.1101/180273 — bioengineering — Posted on 2021-02-11
2549 Large palindromes on the primate X Chromosome are preserved by natural selection
Jackson, E. K.; Bellott, D. W.; Cho, T.-J.; Skaletsky, H.; Hughes, J.; Pyntikova, T.; Page, D. C.
10.1101/2020.12.29.424738 — genomics — Posted on 2021-02-11
2554 CTP regulates membrane-binding activity of the nucleoid occlusion protein Noc
Jalal, A. S. B.; Tran, N. T.; Wu, L. J.; Ramakrishnan, K.; Rejzek, M.; Stevenson, C. E. M.; Lawson, D. M.; Errington, J.; Le, T. B. K.
10.1101/2021.02.11.430593 — microbiology — Posted on 2021-02-11
2556 Functional and taxonomic comparison of mouse and human gut microbiotas using extensive culturing and metagenomics
Beresford-Jones, B. S.; Forster, S. C.; Stares, M. D.; Notley, G.; Viciani, E.; Browne, H. P.; Kumar, N.; Vervier, K.; Almeida, A.; Lawley, T. D.; Pedicord, V. A.
10.1101/2021.02.11.430759 — microbiology — Posted on 2021-02-11
2557 Saccharomyces cerevisiae gene expression during fermentation of Pinot noir wines at industrially relevant scale
Reiter, T.; Montpetit, R.; Byer, S.; Frias, I.; Leon, E.; Viano, R.; Mcloughlin, M.; Halligan, T.; Hernandez, D.; Runnebaum, R.; Montpetit, B.
10.1101/2021.01.11.426308 — microbiology — Posted on 2021-02-11
2558 Transcriptomics provides a genetic signature of vineyard site with insight into vintage-independent regional wine characteristics
Reiter, T.; Montpetit, R.; Byer, S.; Frias, I.; Leon, E.; Viano, R.; Mcloughlin, M.; Halligan, T.; Hernandez, D.; Figueroa-Balderas, R.; Cantu, D.; Steenwerth, K.; Runnebaum, R.; Montpetit, B.
10.1101/2021.01.07.425830 — microbiology — Posted on 2021-02-11
2559 Gys1 antisense therapy rescues neuropathological bases of murine Lafora disease
Ahonen, S.; Nitschke, S.; Grossman, T. R.; Kordasiewicz, H.; Wang, P.; Zhao, X.; Guisso, D. R.; Kasiri, S.; Nitschke, F.; Minassian, B. A.
10.1101/2021.02.11.430846 — neuroscience — Posted on 2021-02-11
2561 Network dynamics underlying OFF responses in the auditory cortex
Bondanelli, G.; Deneux, T.; Bathellier, B.; Ostojic, S.
10.1101/810655 — neuroscience — Posted on 2021-02-11
2563 Emergence of task information from dynamic network interactions in the human brain
Mill, R. D.; Hamilton, J. L.; Winfield, E. C.; Lalta, N.; Chen, R. H.; Cole, M. W.
10.1101/2021.01.26.428276 — neuroscience — Posted on 2021-02-11
2564 Cortical layer-specific modulation of neuronal activity after sensory deprivation due to spinal cord injury
Zaforas, M.; Rosa, J. M.; Alonso-Calvino, E.; Fernandez-Lopez, E.; Miguel-Quesada, C.; Oliviero, A.; Aguilar, J.
10.1101/2020.12.28.424612 — neuroscience — Posted on 2021-02-11
2567 RuBisCO adaptation is more limited by phylogenetic constraint than by catalytic trade-off
Bouvier, J. W.; Emms, D. M.; Rhodes, T.; Bolton, J. S.; Brasnett, A.; Eddershaw, A.; Nielsen, J. R.; Unitt, A.; Whitney, S. M.; Kelly, S.
10.1101/2020.09.15.298075 — plant biology — Posted on 2021-02-11
2568 Crystal structure of a bacterial CNNM magnesium transporter
Chen, Y. S.; Kozlov, G.; Armitano, J.; Moeller, B. J.; Fakih, R.; Rohaim, A.; Roux, B.; Burke, J. E.; Gehring, K.
10.1101/2021.02.11.430706 — biophysics — Posted on 2021-02-11
2569 SARS-CoV-2 variants B.1.351 and B.1.1.248: Escape from therapeutic antibodies and antibodies induced by infection and vaccination
Hoffmann, M.; Arora, P.; Gross, R.; Seidel, A.; Hoernich, B.; Hahn, A.; Krueger, N.; Graichen, L.; Hofmann-Winkler, H.; Kempf, A.; Winkler, M. S.; Schulz, S.; Jaeck, H.-M.; Jahrsdoerfer, B.; Schrezenmeier, H.; Mueller, M.; Kleger, A.; Muench, J.; Poehlmann, S.
10.1101/2021.02.11.430787 — molecular biology — Posted on 2021-02-11
2571 Data-driven analysis of COVID-19 reveals specific severity patterns distinct from the temporal immune response
Lim, J.; Carissimo, G.; Chan, Y.-H.; Fong, S.-W.; Lee, W. W.; Tan, S.-Y.; Lye, D. C.; Young, B. E.; Renia, L.; Fong-Poh NG, L.; Rotzschke, O.; Puan, K. J.; Wang, L. W.; Teng, K. W. W.; Loh, C. Y.; Tan, K. P.; Poh, C. M.; Lee, C. Y.-P.; Yeo, N. K.-W.; Chee, R. S.-L.; Amrun, S. N.; Chang, Z. W.; Tay, M. Z.; Torres-Ruesta, A.; Leo Fernandez, N.; How, W.; K. Andiappan, A.; Duan, K.; Yan, G.; Kalimuddin, S.; Leo, Y.-S.; Ong, S. W. X.; Lee, B.
10.1101/2021.02.10.430668 — immunology — Posted on 2021-02-11
2573 An invariant Trypanosoma vivax vaccine antigen inducing protective immunity
Autheman, D.; Crosnier, C.; Clare, S.; Goulding, D.; Brandt, C.; Harcourt, K.; Tolley, C.; Galaway, F.; Khushu, M.; Ong, H.; Romero Ramirez, A.; Duffy, C.; Jackson, A.; Wright, G. J.
10.1101/2021.02.10.430711 — microbiology — Posted on 2021-02-11
2576 Comprehensive imaging of synaptic activity reveals dendritic growth rules that cluster inputs
Podgorski, K.; Toth, T. D.; Coleman, P.; Opushnyev, S.; Brusco, J.; Hogg, P.; Edgcumbe, P.; Haas, K.
10.1101/2021.02.11.430646 — neuroscience — Posted on 2021-02-11
2577 Fasting reverses drug-resistance in hepatocellular carcinoma through p53-dependent metabolic synergism
Krstic, J.; Reinisch, I.; Schindlmaier, K.; Galhuber, M.; Berger, N.; Kupper, N.; Moyschewitz, E.; Auer, M.; Michenthaler, H.; Noessing, C.; Depaoli, M. R.; Ramadani-Muja, J.; Stryeck, S.; Pichler, M.; Rinner, B.; Deutsch, A. J.; Reinisch, A.; Madl, T.; Zenezini Chiozzi, R.; Heck, A. J.; Huch, M.; Malli, R.; Prokesch, A.
10.1101/2021.02.10.430545 — cancer biology — Posted on 2021-02-11
2579 Shared genetic underpinnings between genetic generalized epilepsy and background EEG oscillations
Stevelink, R.; Luykx, J. J.; Lin, B.; Leu, C.; Lal, D.; Smith, A.; Schijven, D.; Carpay, J.; Rademaker, K.; Baldez, R.; Braun, K.; Jansen, F.; Epi25 Collaborative, ; ILAE Consortium, ; Smit, D.; Koeleman, B.
10.1101/711200 — genetics — Posted on 2021-02-11
2585 TemplateFlow: a community archive of imaging templates and atlases for improved consistency in neuroimaging
Ciric, R.; Lorenz, R.; Thompson, W. H.; Goncalves, M.; MacNicol, E.; Markiewicz, C.; Halchenko, Y.; Ghosh, S. S.; Gorgolewski, K. J.; Poldrack, R.; Esteban, O.
10.1101/2021.02.10.430678 — neuroscience — Posted on 2021-02-11
2590 Hotspot ESR1 mutations are multimodal and contextual drivers of breast cancer metastasis
Li, Z.; Wu, Y.; Yates, M. E.; Tasdemir, N.; Bahreini, A.; Chen, J.; Levine, K. M.; Priedigkeit, N. M.; Ali, S.; Buluwela, L.; Arnesen, S.; Gertz, J.; Richer, J. K.; Troness, B.; El-Ashry, D.; Zhang, Q.; Gerratana, L.; Zhang, Y.; Cristofanilli, M.; Montanez, M. A.; Sundd, P.; Wallace, C. T.; Watkins, S. C.; Zhu, L.; Tseng, G.; Wagle, N.; Carroll, J.; Jank, P.; Denkert, C.; Karsten, M. M.; Blohmer, J.; Park, B. H.; Lucas, P. C.; Atkinson, J. M.; Lee, A. V.; Oesterreich, S.
10.1101/2021.02.10.430701 — cancer biology — Posted on 2021-02-11
2591 Accelerating COVID-19 research with graph mining and transformer-based learning
Tyagin, I.; Kulshrestha, A.; Sybrandt, J.; Matta, K.; Shtutman, M.; Safro, I.
10.1101/2021.02.11.430789 — bioinformatics — Posted on 2021-02-11
2594 Niche-guided tissue patterning by chemomechanical flow lithography
Newman, P. L. H.; Osteil, P.; Anderson, T. A.; Sun, J. Q. J.; Kempe, D.; Biro, M.; Tam, P. P. L.; Shin, J.-W.; Zreiqat, H.
10.1101/2021.02.10.430691 — bioengineering — Posted on 2021-02-11
2595 A Framework for Sensor-based Assessment of Upper-limb Functioning
David, A.; Subash, T.; SKM, V.; Melendez-Calderon, A.; Balasubramanian, S.
10.1101/2021.02.10.430700 — bioengineering — Posted on 2021-02-11
2598 Adjuvanting a subunit SARS-CoV-2 nanoparticle vaccine to induce protective immunity in non-human primates
S Arunachalam, P.; Walls, A. C.; Golden, N.; Atyeo, C.; Fischinger, S.; Li, C.; Aye, P.; Navarro, M. J.; Lai, L.; Edara, V. V.; Roltgen, K.; Rogers, K.; Shirreff, L.; Ferrell, D. E.; Wrenn, S.; Pettie, D.; Kraft, J. C.; Miranda, M. C.; Kepl, E.; Sydeman, C.; Brunette, N.; Murphy, M.; Fiala, B.; Carter, L.; White, A. G.; Trisal, M.; Hsieh, C.-L.; Russell-Lodrigue, K.; Monjure, C.; Dufour, J.; Doyle-Meyer, L.; Bohm, R. B.; Maness, N. J.; Roy, C.; Plante, J. A.; Plante, K. S.; Zhu, A.; Gorman, M. J.; Shin, S.; Shen, X.; Fontenot, J.; Gupta, S.; O Hagan, D. T.; Most, R. V. D.; Rappuoli, R.; Coffma
10.1101/2021.02.10.430696 — immunology — Posted on 2021-02-11
2600 Specialization of actin isoforms derived from the loss of key interactions with regulatory factors
Boiero Sanders, M.; Toret, C.; Antkowiak, A.; Guillotin, A.; Robinson, R. C.; Michelot, A.
10.1101/2021.02.09.430555 — cell biology — Posted on 2021-02-11
2601 Synthetic multistability in mammalian cells
Zhu, R.; del Rio-Salgado, J. M.; Garcia-Ojalvo, J.; Elowitz, M.
10.1101/2021.02.10.430659 — synthetic biology — Posted on 2021-02-11
2604 Gene dosage effects of polyA track engineered hypomorphs
Powell, G. N.; Pavlovic-Djuranovic, S.; Djuranovic, S.
10.1101/2021.02.10.430645 — genetics — Posted on 2021-02-11
2606 Evidence of stock connectivity, hybridization and misidentification in white anglerfish support the need for adopting a genetics-informed fisheries management approach
Aguirre-Sarabia, I.; Diaz-Arce, N.; Pereda-Agirre, I.; Mendibil, I.; Urtizberea, A.; Gerritsen, H. D.; Burns, F.; Holmes, I.; Landa, J.; Coscia, I.; Quincoces, I.; Santurtun, M.; Zanzi, A.; Martinsohn, J. T.; Rodriguez-Ezpeleta, N.
10.1101/2021.02.10.430581 — evolutionary biology — Posted on 2021-02-11
2609 On the distribution of spinal premotor interneurons
Ronzano, R.; Skarlatou, S.; Bannatyne, B. A.; Bhumbra, G. S.; Foster, J. D.; Lancelin, C.; Pocratsky, A.; Ozyurt, M. G.; Smith, C. C.; Todd, A. J.; Maxwell, D. J.; Murray, A. J.; Brownstone, R. M.; Zampieri, N.; Beato, M.
10.1101/2021.02.10.430608 — neuroscience — Posted on 2021-02-11
2613 Mice Make Targeted Saccades
Zahler, S. H.; Taylor, D. E.; Adams, J. M.; Feinberg, E. H.
10.1101/2021.02.10.430669 — neuroscience — Posted on 2021-02-11
2618 An Activator Locks Kv7.1 Channels Open by Electro-Mechanical Uncoupling and Allosterically Modulates its Pore with similarity to phosphatidylinositol-4,5-bisphosphat
Moeller, M.; Schreiber, J. A.; Zaydman, M.; Beller, Z.; Becker, S.; Ritter, N.; Wrobel, E.; Strutz-Seebohm, N.; Decher, N.; Cui, J.; Schmidt, N.; Duefer, M.; Wuensch, B.; Seebohm, G.
10.1101/2021.02.11.430741 — biophysics — Posted on 2021-02-11
2619 Human retinal organoids release extracellular vesicles that regulate gene expression in target human retinal progenitors
Zhou, J.; Flores-Bellver, M.; Pan, J.; Benito-Martin, A.; Shi, C.; Onwumere, O.; Mighty, J.; Qian, J.; Zhong, X.; Hogue, T.; Amponsah-Antwi, B.; Einbond, L.; Gharbaran, R.; Wu, H.; Chen, B.-J.; Zheng, Z.; Tchaikovskaya, T.; Zhang, X.; Peinado, H.; Canto-Soler, V.; Redenti, S.
10.1101/2021.02.10.430690 — developmental biology — Posted on 2021-02-11
2620 A strategy to address dissociation-induced compositional and transcriptional bias for single-cell analysis of the human mammary gland
Engelbrecht, L. K.; Twigger, A.-J.; Ganz, H. M.; Gabka, C. J.; Bausch, A. R.; Lickert, H.; Sterr, M.; Kunze, I.; Khaled, W. T.; Scheel, C. H.
10.1101/2021.02.11.430721 — cell biology — Posted on 2021-02-11
2621 Microtubule lattice defects promote catastrophes.
Rai, A.; Liu, T.; Katrukha, E. A.; Estevez-Gallego, J.; Paterson, I.; Diaz, F.; Kapitein, L. C.; Moores, C. A.; Akhmanova, A.
10.1101/2021.02.11.430743 — cell biology — Posted on 2021-02-11
2624 An opposing self-reinforced odor pre-exposure memory produces latent inhibition in Drosophila
Jacob, P. F.; Vargas-Gutierrez, P.; Okray, Z.; Vietti-Michelina, S.; Felsenberg, J.; Waddell, S.
10.1101/2021.02.10.430636 — neuroscience — Posted on 2021-02-11
2626 CONTEXT-INDEPENDENT FUNCTION OF A CHROMATIN BOUNDARY IN VIVO
Willemin, A.; Lopez-Delisle, L.; Bolt, C. C.; Gadolini, M.-L.; Duboule, D.; Rodriguez-Carballo, E.
10.1101/2021.02.11.430727 — genetics — Posted on 2021-02-11
2629 Mitochondrial Fission Regulates Transcription of Ribosomal Protein Genes in Embryonic Hearts
Zhao, Q.; Yan, S.; Lu, J.; Parker, D. J.; Wu, H.; Sun, Q.; Crossman, D.; Liu, S.; Wang, Q.; Sesaki, H.; Mitra, K.; Liu, K.; Jiao, K.
10.1101/2021.02.10.430627 — developmental biology — Posted on 2021-02-11
2630 ZC3H4 restricts non-coding transcription in human cells
West, S.; Estell, C.; Davidson, L.; Monier, A.; Steketee, P.
10.1101/2021.02.10.430684 — molecular biology — Posted on 2021-02-11
2631 The discriminatory power of the T cell receptor
Pettmann, J.; Huhn, A.; Abu-Shah, E.; Kutuzov, M. A.; Wilson, D. B.; Dustin, M.; Davis, S.; van der Merwe, P. A.; Dushek, O.
10.1101/2020.11.16.384495 — immunology — Posted on 2021-02-11
2633 Sailing in rough waters: examining volatility of fMRI noise
Leppanen, J.; Stone, H.; Lythgoe, D. J.; Williams, S.; Horvath, B.
10.1101/2020.06.19.161570 — neuroscience — Posted on 2021-02-11
2635 Creating Clear and Informative Image-based Figures for Scientific Publications
Jambor, H.; Antonietti, A.; Alicea, B. J.; Audisio, T. L.; Auer, S.; Bhardwaj, V.; Burgess, S. J.; Ferling, I.; Gazda, M. A.; Hoeppner, L. H.; Ilangovan, V.; Lo, H.; Olson, M.; Mohamed, S. Y.; Sarabipour, S.; Varma, A.; Walavalkar, K.; Wissink, E.; Weissgerber, T. L.
10.1101/2020.10.08.327718 — bioinformatics — Posted on 2021-02-11
2638 Characterization and rescue by oxytocin of an atypical thermo-sensory reactivity in neonatal mice lacking the autism-associated gene Magel2.
Caccialupi Da Prato, L.; Abdallah, D.; Point, V.; Schaller, F.; Montheil, A.; Pallesi-Pocachard, E.; Canaan, S.; Gaiarsa, J.-L.; Muscatelli, F.; Matarazzo, V.
10.1101/869487 — neuroscience — Posted on 2021-02-11
2639 A comprehensive urine proteome database generated from patients with various renal conditions and prostate cancer
Swensen, A. C.; He, J.; Fang, A. C.; Ye, Y.; Nicora, C. D.; Shi, T.; Liu, A. Y.; Sigdel, T. K.; Sarwal, M. M.; QIAN, W.-J.
10.1101/2021.02.10.430660 — systems biology — Posted on 2021-02-11
2640 Identification and mechanistic analysis of an inhibitor of the CorC Mg2+ transporter
Huang, Y.; Mu, K.; Teng, X.; Zhao, Y.; Funato, Y.; Miki, H.; Zhu, W.; Xu, Z.; Hattori, M.
10.1101/2021.02.10.430528 — biophysics — Posted on 2021-02-11
2641 Electrical Unfolding of Cytochrome c During Translocation Through a Nanopore Constriction
Tripathi, P.; Benabbas, A.; Mehrafrooz, B.; Yamazaki, H.; Aksimentiev, A.; Champion, P.; Wanunu, M.
10.1101/2021.02.10.430607 — biophysics — Posted on 2021-02-11
2644 Computational Simulation of 4-D Micro-Circular Network in Zebrafish Tail Amputation and Regeneration
Roustaei, M.; Baek, K. I.; Wang, Z.; Cavallero, S.; Satta, S.; Lai, A.; O'Donnell, R.; Vedula, V.; Ding, Y.; Marsden, A. L.; Hsiai, T.
10.1101/2021.02.10.430654 — bioengineering — Posted on 2021-02-11
2645 Comparative proteome signatures of ultra-low input samples by TMT multiplexed Data-Independent Acquisition
Ctortecka, C.; Krssakova, G.; Stejskal, K.; Penninger, J.; Mendjan, S.; Mechtler, K.; Stadlmann, J.
10.1101/2021.02.11.430601 — biochemistry — Posted on 2021-02-11
2646 Rapid genomic convergent evolution in experimental populations of Trinidadian guppies (Poecilia reticulata)
van der Zee, M. J.; Whiting, J. R.; Paris, J. R.; Bassar, R. D.; Travis, J.; Weigel, D.; Reznick, D. N.; Fraser, B. A.
10.1101/2021.02.10.430609 — evolutionary biology — Posted on 2021-02-11
2647 A molecular framework for control of oriented cell division in the Arabidopsis embryo
Vaddepalli, P.; de Zeeuw, T.; Strauss, S.; Buerstenbinder, K.; Liao, C.-Y.; Smith, R.; Weijers, D.
10.1101/2021.02.09.430440 — plant biology — Posted on 2021-02-11
2648 Characterisation of immune cell subsets of tumour infiltrating lymphocytes in brain metastases
Kalita-de Croft, P.; Chittoory, H.; Nguyen, T.; Saunus, J. M.; Gyeong Kim, W.; McCart Reed, A.; Lim, M.; De Luca, X. M.; Ferguson, K.; Niland, C.; Mazzieri, R.; Dolcetti, R.; Simpson, P. T.; Lakhani, S. R.
10.1101/2021.02.10.430531 — pathology — Posted on 2021-02-11
2649 Multiplatform Computational Analysis of Mast Cells in Adrenocortical Carcinoma Tumor Microenvironment
Baechle, J. J.; Hanna, D. N.; Konjeti, S. R.; Rathmell, J. C.; Rathmell, W. K.; Baregamian, N.
10.1101/2021.02.09.430462 — cancer biology — Posted on 2021-02-11
2650 Genome-wide prediction and integrative functional characterization of Alzheimer's disease-associated genes
Lin, C.; Li, H.-D.; Deng, C.; Liu, W.; Erhardt, S.; WU, F.; Zhao, X.; Wang, J.; Wang, D.; Hu, B.; Wang, J.
10.1101/2021.02.09.430536 — bioinformatics — Posted on 2021-02-10
2651 Accommodating site variation in neuroimaging data using hierarchical and Bayesian models
Bayer, J. M. M.; Dinga, R.; Kia, S. M.; Kottaram, A. R.; Wolfers, T.; Lv, J.; Zalesky, A.; Schmaal, L.; Marquand, A.
10.1101/2021.02.09.430363 — bioinformatics — Posted on 2021-02-11
2653 An integrated strategy reveals complex glycosylation of erythropoietin using top-down and bottom-up mass spectrometry
Guan, Y.; Zhang, M.; Gaikwad, M.; Voss, H.; Fazel, R.; Ansari, S.; Shen, H.; Wang, J.; Hartmut, S.
10.1101/2021.02.09.430553 — biochemistry — Posted on 2021-02-10
2655 CRISPR perturbations at many coronary artery disease loci impair vascular endothelial cell functions
Wünnemann, F.; Fotsing Tadjo, T.; Beaudoin, M.; Lalonde, S.; Sin Lo, K.; Lettre, G.
10.1101/2021.02.10.430527 — genomics — Posted on 2021-02-11
2657 The UCR Minicore: a valuable resource for cowpea research and breeding
Munoz-Amatriain, M.; Lo, S.; Herniter, I. A.; Boukar, O.; Fatokun, C.; Carvalho, M.; Castro, I.; Guo, Y.-N.; Huynh, B.-L.; Roberts, P. A.; Carnide, V.; Close, T. J.
10.1101/2021.02.09.430326 — genetics — Posted on 2021-02-11
2663 Validating a high-throughput tracking system: ATLAS as a regional-scale alternative to GPS
Beardsworth, C. E.; Gobbens, E.; van Maarseveen, F.; Denissen, B.; Dekinga, A.; Nathan, R.; Toledo, S.; Bijleveld, A. I.
10.1101/2021.02.09.430514 — ecology — Posted on 2021-02-10
2665 Nanocharacterisation of extracellular vesicles uncovers the correlation between isolation methods, physicochemical composition and their biological function
Phan, T. H.; Divakarla, K. S.; Yeo, J. H.; Lei, Q.; Tharkar, P.; Pansani, T. N.; Leslie, K. G.; Tong, M.; Coleman, V. A.; Jamting, A.; Plessis, M.-D. D.; New, E. J.; KALIONIS, B.; Demokritou, P.; Woo, H.-K.; Cho, Y.-K.; Chrzanowski, W.
10.1101/2021.02.09.430523 — cell biology — Posted on 2021-02-10
2666 Sub-diffraction error mapping for localization microscopy images
Marsh, R. J.; Costello, I.; Gorey, M.-A.; Ma, D.; Huang, F.; Gautel, M.; Parsons, M.; Cox, S.
10.1101/2021.02.10.427128 — cell biology — Posted on 2021-02-10
2674 Abscisic-acid-dependent regulation of Arabidopsis thaliana ammonium transport relies on ABI1 control of CIPK23 and AMT1
Ganz, P.; Porras-Murillo, R.; Ijato, T.; Menz, J.; Straub, T.; Stuehrwohldt, N.; Moradtalab, N.; Ludewig, U.; Neuhaeuser, B.
10.1101/2021.02.09.430435 — plant biology — Posted on 2021-02-10
2675 Up-regulation of bundle sheath electron transport capacity under limiting light in C4 Setaria viridis
Ermakova, M.; Bellasio, C.; Fitzpatrick, D.; Furbank, R. T.; Mamedov, F.; von Caemmerer, S.
10.1101/2021.02.10.430537 — plant biology — Posted on 2021-02-10
2678 The seasonal dynamics of bud dormancy in grapevine suggest a regulated checkpoint prior to acclimation
Velappan, Y.; Chabikwa, T. G.; Considine, J. A.; Agudelo-Romero, P.; Foyer, C. H.; Signorelli, S.; Considine, M. J.
10.1101/2021.02.09.430520 — plant biology — Posted on 2021-02-10
2681 Development of a Triazolobenzodiazepine-Based PET Probe for Subtype-Selective Vasopressin 1A Receptor Imaging
Haider, A.; Xiao, Z.; Xia, X.; Chen, J.; Van, R. S.; Kuang, S.; Zhao, C.; Rong, J.; Shao, T.; Ramesh, P.; Aravind, A.; Shao, Y.; Ran, C.; Young, L.; Liang, S. H.
10.1101/2021.02.09.430516 — pharmacology and toxicology — Posted on 2021-02-10
2685 Genome Warehouse: A Public Repository Housing Genome-scale Data
Chen, M.; Ma, Y.; Wu, S.; Zheng, X.; Kang, H.; Sang, J.; Xu, X.; Hao, L.; Li, Z.; Gong, Z.; Xiao, J.; Zhang, Z.; Zhao, W.; Bao, Y.
10.1101/2021.02.10.430367 — bioinformatics — Posted on 2021-02-10
2691 DROP: Molecular voucher database for identification of Drosophila parasitoids
Lue, C.-H.; Buffington, M. L.; Scheffer, S.; Lewis, M.; Elliott, T. A.; Lindsey, A. R. I.; Driskell, A.; Jandova, A.; Kimura, M. T.; Carton, Y.; Kula, R. R.; Schlenke, T. A.; Mateos, M.; Govind, S.; Varaldi, J.; Guerrier, E.; Giorgini, M.; Wang, X.; Hoelmer, K.; Daane, K. M.; Abram, P. K.; Pardikes, N. A.; Brown, J. J.; THIERRY, M.; Poirie, M.; Goldstein, P.; Miller, S. E.; Tracey, D.; Davis, J. S.; Jiggins, F. M.; Wertheim, B.; Lewis, O.; Leips, J.; Staniczenko, P. P. A.; Hrcek, J.
10.1101/2021.02.09.430471 — genomics — Posted on 2021-02-10
2693 Glycan-Based Shaping Of The Microbiota During Primate Evolution
Singh, S.; Bastos-Amador, P.; Thompson, J. A.; Truglio, M.; Yilmaz, B.; Cardoso, S.; Sobral, D.; Soares, M. P.
10.1101/2021.02.10.430443 — evolutionary biology — Posted on 2021-02-10
2695 A masculinizing supergene underlies an exaggerated male reproductive morph in a spider.
Hendrickx, F.; De Corte, Z.; Sonet, G.; Van Belleghem, S. M.; Kostlbacher, S.; Vangestel, C.
10.1101/2021.02.09.430505 — evolutionary biology — Posted on 2021-02-10
2698 rasterdiv - an Information Theory tailored R package for measuring ecosystem heterogeneity from space: to the origin and back
Rocchini, D.; Thouverai, E.; Marcantonio, M.; Iannacito, M.; Da Re, D.; Torresani, M.; Bacaro, G.; Bazzichetto, M.; Bernard, A.; Foody, G. M.; Furrer, R.; Kleijn, D.; Larsen, S.; Lenoir, J.; Malavasi, M.; Marchetto, E.; Messori, F.; Montaghi, A.; Moudry, V.; Naimi, B.; Ricotta, C.; Rossini, M.; Santi, F.; Santos, M. J.; Schaepman, M.; Schneider, F.; Schuh, L.; Silvestri, S.; Simova, P.; Skidmore, A. K.; Tattoni, C.; Tordoni, E.; Vicario, S.; Zannini, P.; Wegmann, M.
10.1101/2021.02.09.430391 — ecology — Posted on 2021-02-10
2701 The biogenesis and function of nucleosome arrays
Singh, A. K.; Schauer, T.; Pfaller, L.; Straub, T.; Mueller-Planitz, F.
10.1101/2021.02.10.429500 — molecular biology — Posted on 2021-02-10
2705 Single-cell analysis of the ventricular-subventricular zone reveals signatures of dorsal and ventral adult neurogenic lineages
Redmond, S. A.; Cebrian Silla, A.; Assis Nascimento, M.; Mansky, B.; Wu, D.; Obernier, K.; Romero Rodriguez, R.; Lim, D. A.; Alvarez-Buylla, A.
10.1101/2021.02.10.430525 — neuroscience — Posted on 2021-02-10
2706 An endogenous opioid circuit determines state-dependent appetitive behavior
Castro, D. C.; Oswell, C. S.; Zhang, E. T.; Pedersen, C. E.; Piantadosi, S. C.; Rossi, M. A.; Hunker, A.; Guglin, A.; Moron, J. A.; Zweifel, L. S.; Stuber, G. D.; Bruchas, M. R.
10.1101/2021.02.10.430657 — neuroscience — Posted on 2021-02-10
2708 Vocal plasticity in harbour seal pups
Torres Borda, L.; Jadoul, Y.; Rasilo, H.; Salazar Casals, A.; Ravignani, A.
10.1101/2021.02.10.430617 — animal behavior and cognition — Posted on 2021-02-10
2710 Neuroprotective and Mitoprotective Effects of Lemon IntegroPectin on SH-SY5Y Cells
Nuzzo, D.; Picone, P.; Giardina, C.; Scordino, M.; Mudo', G.; Pagliaro, M.; Scurria, A.; Meneguzzo, F.; Ilharco, L. M.; Fidalgo, A.; Presentato, A.; Alduina, R. V.; Ciriminna, R.; Di Liberto, V.
10.1101/2021.02.09.430380 — neuroscience — Posted on 2021-02-10
2713 Full assembly of HIV-1 particles requires assistance of the membrane curvature factor IRSp53.
Inamdar, K.; Tsai, F.-C.; dePoret, A.; Dibsy, R.; Manzi, J.; Merida, P.; Muller, R.; Lappalainen, P.; Roingeard, P.; Mak, J.; Bassereau, P.; Favard, C.; MURIAUX, D.
10.1101/2021.02.10.430663 — biophysics — Posted on 2021-02-10
2714 Structural variants in Chinese population and their impact on phenotypes, diseases and population adaptation
Wu, Z.; Jiang, Z.; Li, T.; Xie, C.; Zhao, L.; Yang, j.; Ouyang, S.; Liu, Y.; Li, T.; Xie, Z.
10.1101/2021.02.09.430378 — genetics — Posted on 2021-02-10
2715 Role of GM-CSF in regulating metabolism and mitochondrial functions critical to macrophage proliferation
Wessendarp, M.; Watanabe, M.; Liu, S.; Stankiewicz, T.; Ma, Y.; Shima, K.; Chalk, C.; Carey, B.; Romick-Rosendale, L.; Filippi, M.-D.; Arumugam, P.
10.1101/2021.02.10.430444 — cell biology — Posted on 2021-02-10
2716 Transgenerational Regulation of Sexual Attractiveness in C. elegans Nematodes
Toker, I. A.; Lev, I.; Mor, Y.; Gurevich, Y.; Fisher, D.; Houri-Zeevi, L.; Antonova, O.; Hadany, L.; Shaham, S.; Rechavi, O.
10.1101/2020.11.18.389387 — molecular biology — Posted on 2021-02-10
2719 Host tropism determination by convergent evolution of immunological evasion in the Lyme disease system
Hart, T. M.; Dupuis, A. P.; Tufts, D. M.; Blom, A. M.; Starkey, S.; Rego, R. O. M.; Ram, S.; Kraiczy, P.; Kramer, L. D.; Diuk-Wasser, M. A.; Kolokotronis, S.-O.; Lin, Y.-P.
10.1101/2021.02.09.430532 — microbiology — Posted on 2021-02-10
2722 A new variant of ASIC2 mediates sodium retention in nephrotic syndrome
Fila, M.; Sassi, A.; Brideau, G.; Morla, L.; Houillier, P.; Walter, C.; Gennaoui, M.; Collignon, L.; Keck, M.; Planelles, G.; Bakouh, N.; Peuchmaur, M.; Deschenes, G.; Anegon, I.; Remy, S.; Vogt, B.; Crambert, G.; Doucet, A.
10.1101/2021.02.09.430231 — pathology — Posted on 2021-02-10
2726 Protomer alignment modulates specificity of RNA substrate recognition by Ire1
Li, W.; Crotty, K.; Ruiz, D. G.; Voorhies, M.; Rivera, C.; Sil, A.; Mullins, D.; Jacobson, M.; Peschek, J.; Walter, P.
10.1101/2021.02.10.430655 — biochemistry — Posted on 2021-02-10
2727 N-glycosylation on Oryza Sativa Root Germin-like Protein 1 is conserved but not required for stability or activity
Rubbab, T.; Pegg, C. L.; Phung, T. K.; Nouwens, A. S.; Yeo, B. K. Y.; Zacchi, L. F.; Muhammad, A.; Naqvi, S. M. S. S.; Schulz, B. L.
10.1101/2021.02.09.430526 — biochemistry — Posted on 2021-02-10
2728 Succinate is Broadly Tissue-Permeant and Uncouples Mitochondrial Respiration from ATP Synthesis
Hass, D. T.; Robbings, B. M.; Bisbach, C. M.; Giering, E.; Mundinger, T. O.; Sadilek, M.; Sweet, I. R.; Hurley, J. B.
10.1101/2021.02.10.430650 — biochemistry — Posted on 2021-02-10
2729 Comparative analysis of mammal genomes unveils key genomic variability for human lifespan.
Farre, X.; Molina, R.; Barteri, F.; Timmers, P.; Joshi, P.; Oliva, B.; Acosta, S.; Esteve-Altava, B.; Navarro, A.; Muntane, G.
10.1101/2021.02.09.430384 — genomics — Posted on 2021-02-10
2733 Capsule protects against intracellular killing and enables vascular endothelial cell translocation during invasive pneumococcal disease
Brissac, T.; Martinez, E.; Kruckow, K. L.; Riegler, A. N.; Ganaie, F.; Im, H.; Bakshi, S.; Arroyo-Diaz, N. M.; Spencer, B.; Saad, J. S.; Nahm, M. H.; Orihuela, C. J.
10.1101/2021.02.10.430484 — microbiology — Posted on 2021-02-10
2737 Bifurcated monocyte states are predictive of mortality in severe COVID-19
Cillo, A. R.; Somasundaram, A.; Shan, F.; Cardello, C.; Workman, C. J.; Kitsios, G. D.; Ruffin, A.; Kunning, S.; Lampenfeld, C.; Onkar, S.; Grebinowski, S.; Deshmukh, G.; Methe, B.; Liu, C.; Nambulli, S.; Andrews, L.; Duprex, W. P.; Joglekar, A. J.; Benos, P. V.; Ray, P.; Ray, A.; McVerry, B. J.; Zhang, Y.; Lee, J. S.; Das, J.; Singh, H.; Morris, A.; Bruno, T. C.; Vignali, D. A.
10.1101/2021.02.10.430499 — immunology — Posted on 2021-02-10
2738 A Safe and Effective Mucosal RSV Vaccine Consisting of RSV Phosphoprotein and Flagellin Variant
Zhao, B.; Yang, J.; He, B.; Li, X.; Yan, H.; Liu, S.; Yang, Y.; Zhou, D.; Liu, B.; Fan, X.; Zhong, M.; Zhang, E.; Zhang, F.; Zhang, Y.; Chen, Y.-Q.; Jiang, S.; Yan, H.
10.1101/2021.02.09.430425 — immunology — Posted on 2021-02-10
2739 Catestatin regulates the colonic mucus layer in inflammatory bowel disease
Muntjewerff, E.; Lutter, L.; Tang, K.; Kea-te Lindert, M.; Fransen, J.; Oldenburg, B.; Mahata, S. K.; van den Bogaart, G.
10.1101/2021.02.09.430377 — immunology — Posted on 2021-02-10
2744 Immunomodulatory Contribution of Mast Cells to the Biomaterial Microenvironment
Wang, R. M.; Ungerleider, J.; Kawakami, Y.; Kawakami, Y.; Kawakami, T.; Christman, K.
10.1101/2020.07.31.231852 — bioengineering — Posted on 2021-02-10
2748 Patient derived models of bladder cancer amplify tumor specific gene expression compared to surgical specimen while maintaining gene expression of molecular subtype and epithelial mesenchymal transition markers
Mastri, M.; Ramakrishnan, S.; Shah, S.; Karasik, E.; Gillard, B. M.; Moser, M. M.; Farmer, B. K.; Chatta, G. S.; Woloszynska, A.; Eng, K. H.; Foster, B. A.; HUSS, W. J.
10.1101/2021.02.10.430614 — cancer biology — Posted on 2021-02-10
2750 In vitro evolution of Remdesivir resistance reveals genome plasticity of SARS-CoV-2
Szemiel, A. M.; Merits, A.; Orton, R. J.; MacLean, O.; Wickenhagen, A.; Lieber, G.; Pinto, R. M.; Turnbull, M. L.; Wang, S.; Mair, D.; da Silva Filipe, A.; Willett, B. J.; Wilson, S. J.; Patel, A. H.; Thomson, E. C.; Palmarini, M.; Kohl, A.; Stewart, M. E.
10.1101/2021.02.01.429199 — microbiology — Posted on 2021-02-10
2751 SARS-CoV-2 infection models using in vivo and in vitro hACE2-lentivirus transduction
Rawle, D. J.; Le, T. T.; Dumenil, T.; Yan, K.; Tang, B.; Bishop, C.; Suhrbier, A.
10.1101/2021.02.09.430547 — microbiology — Posted on 2021-02-10
2753 Naive human B cells can neutralize SARS-CoV-2 through recognition of its receptor binding domain
Feldman, J.; Bals, J.; Denis, K. S.; Lam, E. C.; Hauser, B. M.; Ronsard, L.; Sangesland, M.; Moreno, T. B.; Okonkwo, V.; Hartojo, N.; Balazs, A. B.; Lingwood, D.; Schmidt, A. G.
10.1101/2021.02.02.429458 — immunology — Posted on 2021-02-10
2756 Cardiac RyR N-terminal region biosensors for FRET-based high-throughput screening
Zhang, J.; Yuen, S. M. W. K.; Schwarz, J. A.; Treinen, L. M.; Tung, C.-C.; Rebbeck, R. T.; Ro?man, K.; Svensson, B.; Aldrich, C. C.; Thomas, D. D.; Van Petegem, F.; Cornea, R. L.
10.1101/2021.02.07.430153 — biophysics — Posted on 2021-02-10
2758 Catching SARS-CoV-2 by sequence hybridization: a comparative analysis
Rehn, A.; Braun, P.; Knuepfer, M.; Woelfel, R.; Antwerpen, M. H.; Walter, M. C.
10.1101/2021.02.05.429917 — genomics — Posted on 2021-02-10
2759 CCG*CGG interruptions in high penetrance SCA8 families increase RAN translation and protein toxicity
Perez, B. A.; Shorrock, H. K.; Banez-Coronel, M.; Laboissonniere, L. A.; Reid, T.; Ikeda, Y.; Reddy, K.; Gomez, C. M.; Bird, T.; Ashizawa, T.; Schut, L. J.; Brusco, A.; Berglund, A.; Hasholt, L. F.; Nielsen, J. E.; Subramony, S. H.; Ranum, L. P. W.
10.1101/2021.02.08.430311 — genetics — Posted on 2021-02-10
2760 Rapid spread of a symbiotic virus in a major crop pest following wide-scale adoption of Bt-cotton in China
Wu, K.; Xiao, Y.; Xu, P.; Wilson, K.; Bravo, A.; Soberon, M.; Yang, X.; Yuan, H.; Jin, M.; Zheng, W.; Li, W.
10.1101/2021.02.08.430243 — ecology — Posted on 2021-02-10
2762 Deletion of Serf2 shifts amyloid conformation in an Aβ amyloid mouse model
Stroo, E.; Janssen, L.; Sin, O.; Hogewerf, W.; Koster, M. H.; Harkema, L.; Youssef, S. A.; beschorner, N.; Wolters, A. H. G.; Bakker, B.; Thathiah, A.; Foijer, F.; van de Sluis, B.; van Deursen, J.; Jucker, M.; de Bruin, A.; Nollen, E.
10.1101/2021.01.05.423442 — molecular biology — Posted on 2021-02-10
2764 Site-specific O-glycosylation analysis of SARS-CoV-2 spike protein produced in insect and human cells
Bagdonaite, I.; Thompson, A. J.; Wang, X.; Soegaard, M.; Fougeroux, C.; Frank, M.; Diedrich, J. K.; Yates, J. R.; Salanti, A.; Vakhrushev, S. Y.; Paulson, J. C.; Wandall, H. H.
10.1101/2021.02.03.429627 — molecular biology — Posted on 2021-02-10
2766 Genetic models of latent tuberculosis in mice reveal differential control by innate and adaptive immunity
Su, H.; Lin, K.; Tiwari, D.; Healy, C.; Trujillo, C.; Liu, Y.; Schnappinger, D.; Ehrt, S.
10.1101/2021.02.08.430271 — microbiology — Posted on 2021-02-10
2767 Emergence of NADP+-reducing enzymes in Escherichia coli central metabolism via adaptive evolution
Bouzon, M.; Döring, V.; Dubois, I.; Berger, A.; Stoffel, G. M. M.; Calzadiaz Ramirez, L.; Meyer, S.; Foure, M.; Roche, D.; Perret, A.; Erb, T. J.; Bar-Even, A.; Lindner, S. N.
10.1101/2021.02.08.430375 — microbiology — Posted on 2021-02-10
2768 Adoptive transfer of allogeneic gamma delta T cells promotes HIV replication in a humanized mouse model
Biradar, S.; Agarwal, Y.; Lotze, M. T.; Rinaldo, C. R.; Bility, M. T.; Mailliard, R. B.
10.1101/2021.02.08.430263 — immunology — Posted on 2021-02-10
2769 C1q binding to surface-bound IgG is stabilized by C1r2s2 proteases
Zwarthoff, S. A.; Widmer, K.; Kuipers, A.; Strasser, J.; Ruyken, M.; Aerts, P.; de Haas, C. J. C.; Ugurlar, D.; Vidarsson, G.; van Strijp, J.; Gros, P.; Parren, P.; van Kessel, K. P. M.; Preiner, J.; Beurskens, F. J.; Schuurman, J.; Ricklin, D.; Rooijakkers, S. H. M.
10.1101/2021.02.08.430229 — immunology — Posted on 2021-02-10
2770 Alternative splicing of auxiliary β2-subunits stabilizes Cav2.3 Ca2+ channel activity in continuously active midbrain dopamine neurons
Siller, A.; Hofer, N. T.; Tomagra, G.; Wiederspohn, N.; Hess, S.; Benkert, J.; Gaifullina, A.; Spaich, D.; Duda, J.; Poetschke, C.; Vilusic, K.; Fritz, E. M.; Schneider, T.; Kloppenburg, P.; Liss, B.; Carabelli, V.; Carbone, E.; Ortner, N. J.; Striessnig, J.
10.1101/2021.02.10.430224 — neuroscience — Posted on 2021-02-10
2771 A novel and specific regulator of neuronal V-ATPase in Drosophila
Dulac, A.; Issa, A.-R.; Sun, J.; Matassi, G.; Cherif-Zahar, B.; Cattaert, D.; Birman, S.
10.1101/2021.02.08.430253 — neuroscience — Posted on 2021-02-10
2773 A rigid body framework for multi-cellular modelling
Brown, P. J.; Green, J. E. F.; Binder, B. J.; Osborne, J. M.
10.1101/2021.02.10.430170 — systems biology — Posted on 2021-02-10
2774 A user manual to measure gas diffusion kinetics in plants: Pneumatron construction, operation and data analysis
Trabi, C.; Pereira, L.; Guan, X.; Miranda, M. T.; Bittencourt, P. R. d. L.; Oliveira, R. S.; Ribeiro, R. V.; Jansen, S.
10.1101/2021.02.08.430283 — plant biology — Posted on 2021-02-10
2775 Root-to-shoot iron partitioning in Arabidopsis requires IRON-REGULATED TRANSPORTER1 (IRT1)
Quintana, J.; Bernal, M. I.; Scholle, M.; Holländer-Czytko, H.; Nga, N.; Piotrowski, M.; Mendoza-Cozatl, D.; Haydon, M. J.; Kraemer, U.
10.1101/2021.02.08.430285 — plant biology — Posted on 2021-02-10
2777 High-Intensity Interval Training Remodels the Proteome and Acetylome of Human Skeletal Muscle
Hostrup, M.; Lemminger, A. K.; Stocks, B.; Gonzalez-Franquesa, A.; Larsen, J. K.; Thomassen, M.; Weinert, B.; Bangsbo, J.; Deshmukh, A. S.
10.1101/2021.02.10.430602 — physiology — Posted on 2021-02-10
2778 RNF43 inhibits WNT5A driven signaling and suppresses melanoma invasion
Radaszkiewicz, T.; Noskova, M.; Gömöryova, K.; Vondalova Blanarova, O.; Radaszkiewicz, K. A.; Pickova, M.; Vichova, R.; Gybel, T.; Kaiser, K.; Demkova, L.; Kucerova, L.; Potesil, D.; Zdrahal, Z.; Soucek, K.; Bryja, V.
10.1101/2021.02.08.430210 — cancer biology — Posted on 2021-02-10
2779 Topology-based Sparsification of Graph Annotations
Danciu, D.; Karasikov, M.; Mustafa, H.; Kahles, A.; Ratsch, G.
10.1101/2020.11.17.386649 — bioinformatics — Posted on 2021-02-10
2781 Testing for parallel genomic and epigenomic footprints of adaptation to urban life in a passerine bird
Caizergues, A. E.; Le Luyer, J.; Gregoire, A.; Szulkin, M.; Senar, J. C.; Charmantier, A.; Perrier, C.
10.1101/2021.02.10.430452 — genomics — Posted on 2021-02-10
2783 Pathfinder: A gamified measure to integrate general cognitive ability into the biological, medical and behavioural sciences
Malanchini, M.; Rimfeld, K.; Gidziela, A.; Cheesman, R.; Allegrini, A. G.; Shakeshaft, N.; Schofield, K.; Packer, A.; Ogden, R.; McMillan, A.; Ritchie, S. J.; Dale, P. S.; Eley, T. C.; von Stumm, S.; Plomin, R.
10.1101/2021.02.10.430571 — genetics — Posted on 2021-02-10
2789 Differential bioactivity of four BMP-family members as function of biomaterial stiffness
SALES RAMOS, A.; KHODR, V.; MACHILLOT, P.; FOUREL, L.; GUEVARA GARCIA, A.; MIGLIORINI, E.; ALBIGES RIZO, C.; PICART, C.
10.1101/2021.02.10.430282 — cell biology — Posted on 2021-02-10
2790 Mechanism of Interaction of BMP and Insulin Signaling in C. elegans Development and Homeostasis
Clark, J. F.; Ciccarelli, E. J.; Kayastha, P.; Ranepura, G.; Hasan, M. S.; Melendez, A.; Savage-Dunn, C.
10.1101/777805 — cell biology — Posted on 2021-02-10
2791 Long non-coding RNA Neat1 is a key translational regulator in hypoxia.
Godet, A.-C.; David, F.; Roussel, E.; Hantelys, F.; Morfoisse, F.; Alves, J.; Pujol, F.; Ader, I.; Bertrand, E.; Burlet-Schiltz, O.; Froment, C.; Henras, A.; Vitali, P.; Lacazette, E.; Tatin, F.; Garmy-Susini, B.; Prats, A.-C.
10.1101/2021.02.10.430272 — molecular biology — Posted on 2021-02-10
2797 The Size-Weight Illusion is unimpaired in individuals with a history of congenital visual deprivation
Pant, R.; Guerreiro, M. J. S.; Ley, P.; Bottari, D.; Shareef, I.; Kekunnaya, R.; Roeder, B.
10.1101/2021.02.10.430572 — neuroscience — Posted on 2021-02-10
2800 SLC4A2 Anion Exchanger Promotes Tumor Cell Malignancy via Enhancing H+ Leak across Golgi Membranes
Khosrowabadi, E.; Rivinoja, A.; Risteli, M.; Tuomisto, A.; Salo, T.; Makinen, M.; Kellokumpu, S.
10.1101/2021.02.09.428406 — cancer biology — Posted on 2021-02-10
2801 Methylation of KRAS at lysine 182 and 184 by SETD7 promotes KRAS degradation
Chiang, C.; Xiao, T.; Fan, S.; Zheng, H.; Li, S.; Guo, W.; Zhang, M.; Zhong, C.; Zeng, J.; Zheng, D.
10.1101/2021.02.10.429309 — cancer biology — Posted on 2021-02-10
2805 SALTS: SURFR (small noncoding RNA) And LAGOOn (long noncoding RNA) Transcriptomics Suite
Kasukurthi, M. V.; Houserova, D.; Huang, Y. M.; Barchie, A. A.; Roberts, J. T.; Li, D.; Wu, B.; Huang, J.; Borchert, G. M.
10.1101/2021.02.08.430280 — bioinformatics — Posted on 2021-02-10
2808 SPARC Data Structure: Rationale and Design of a FAIR Standard for Biomedical Research Data
Bandrowski, A.; Grethe, J. S.; Pilko, A.; Gillespie, T. H.; Pine, G.; Patel, B.; Surles-Zeiglera, M.; Martone, M. E.
10.1101/2021.02.10.430563 — bioinformatics — Posted on 2021-02-10
2810 Machine learning reveals cryptic dialects that guide mate choice in a songbird
Wang, D.; Forstmeier, W.; Farine, D.; Maldonado-Chaparro, A. A.; Martin, K.; Pei, Y.; Alarcon-Nieto, G.; Klarevas-Irby, J. A.; Ma, S.; Aplin, L. M.; Kempenaers, B.
10.1101/2021.02.08.430277 — animal behavior and cognition — Posted on 2021-02-10
2813 Cas9 targeted enrichment of mobile elements using nanopore sequencing
McDonald, T. L.; Zhou, W.; Castro, C. P.; Mumm, C.; Switzenberg, J. A.; Mills, R. E.; Boyle, A. P.
10.1101/2021.02.10.430605 — genetics — Posted on 2021-02-10
2818 Cardiopharyngeal deconstruction and ancestral tunicate sessility
Ferrandez-Roldan, A.; Fabrega-Torrus, M.; Sanchez-Serna, G.; Duran-Bello, E.; Joaquin-Lluis, M.; Garcia-Fernandez, J.; Albalat, R.; Canestro, C.
10.1101/2021.02.10.430586 — evolutionary biology — Posted on 2021-02-10
2824 How to count your bugs?
Onufrieva, K. S.; Onufriev, A. V.
10.1101/2021.02.08.430281 — ecology — Posted on 2021-02-10
2825 Harmful Algal Bloom-Forming Organism Responds to Nutrient Stress Distinctly From Model Phytoplankton
McLean, C.; Haley, S. T.; Swarr, G. J.; Kido Soule, M. C.; Dyrhman, S. T.; Kujawinski, E. B.
10.1101/2021.02.08.430350 — ecology — Posted on 2021-02-10
2828 Deletion of Serf2 shifts amyloid conformation in an Aβ amyloid mouse model
Stroo, E.; Janssen, L.; Sin, O.; Hogewerf, W.; Koster, M. H.; Harkema, L.; Youssef, S. A.; beschorner, N.; Wolters, A. H. G.; Bakker, B.; Thathiah, A.; Foijer, F.; van de Sluis, B.; van Deursen, J.; Jucker, M.; de Bruin, A.; Nollen, E.
10.1101/2021.01.05.423442 — molecular biology — Posted on 2021-02-10
2830 Establishment of a reverse genetic system from a bovine derived Influenza D virus isolate.
Holwerda, M.; Laloli, L.; Wider, M.; Schoenecker, L.; Becker, J.; Meylan, M.; Dijkman, R.
10.1101/2021.02.10.430577 — microbiology — Posted on 2021-02-10
2832 Dissociable Roles of Pallidal Neuron Subtypes in Regulating Motor Patterns
Cui, Q.; Pamukcu, A.; Cherian, S.; Chang, I. Y.; Berceau, B.; Xenias, H.; Higgs, M.; Rajamanickam, S.; Chen, Y.; Du, X.; Zhang, Y.; McMorrow, H.; Abecassis, Z.; Boca, S.; Justice, N.; Wilson, C.; Chan, C. S.
10.1101/2020.08.23.263053 — neuroscience — Posted on 2021-02-10
2834 In vivo optogenetic stimulation of the primate retina activates the visual cortex after long-term transfection
Chaffiol, A.; Provansal, M.; Joffrois, C.; Blaize, K.; Labernede, G.; Goulet, R.; Burban, E.; Brazhnikova, E.; Duebel, J.; Pouget, P.; Sahel, J.-A.; Picaud, S.; Gauvain, G.; Arcizet, F.
10.1101/2021.02.09.427243 — neuroscience — Posted on 2021-02-10
2838 Resting-state brain activity can predict target-independent aptitude in fMRI-neurofeedback training
Nakano, T.; Takamura, M.; Nishimura, H.; Machizawa, M.; Ichikawa, N.; Yoshino, A.; Okada, G.; Okamoto, Y.; Yamawaki, S.; Yamada, M.; Suhara, T.; Yoshimoto, J.
10.1101/2021.02.08.430334 — neuroscience — Posted on 2021-02-10
2841 CASP microdomain formation requires cross cell wall stabilization of domains and non-cell autonomous action of LOTR1
Kolbeck, A.; Marhavy, P.; De Bellis, D.; Li, B.; Kamiya, T.; Fujiwara, T.; Kalmbach, L.; Geldner, N.
10.1101/2020.08.21.261255 — plant biology — Posted on 2021-02-10
2842 An angiosperm NLR atlas reveals that NLR gene reduction is associated with ecological specialization and signal transduction component deletion
Liu, Y.; Zeng, Z.; Li, Q.; Jiang, X.-M.; Jiang, Z.; Tang, J.-H.; Zhang, Y.-M.; Chen, D.; Wang, Q.; Chen, J.-Q.; Shao, Z.-Q.
10.1101/2021.02.10.430603 — plant biology — Posted on 2021-02-10
2844 Diet High in Soybean Oil Increases Susceptibility to Colitis in Mice
Deol, S. P.; Ruegger, P.; Logan, G.; Shawki, A.; Li, J.; Mitchell, J.; Yu, J.; Piamthai, V.; Radi, S. H.; Newman, J.; Fiehn, O.; McCole, D.; Nair, M. G.; Hsiao, A.; Borneman, J.; Sladek, F. M.
10.1101/2021.02.08.430328 — physiology — Posted on 2021-02-10
2846 On the application of BERT models for nanopore methylation detection
Zhang, Y.-z.; Hatakeyama, S.; Yamaguchi, K.; Furukawa, Y.; Miyano, S.; Yamaguchi, R.; Imoto, S.
10.1101/2021.02.08.430070 — bioinformatics — Posted on 2021-02-10
2850 Reversible blood-brain barrier opening utilizing the membrane active peptide melittin in vitro and in vivo
Linville, R. M.; Komin, A.; Lan, X.; DeStefano, J. G.; Chu, C.; Liu, G.; Walczak, P.; Hristova, K.; Searson, P. C.
10.1101/2021.02.09.430012 — bioengineering — Posted on 2021-02-10
2851 Gene expression plasticity, genetic variation and fatty acid remodelling in divergent populations of a tropical bivalve species
le luyer, J.; Milhade, L.; Reisser, C. M.; Soyez, C.; Monaco, C. J.; Belliard, C.; Le Moullac, G.; Ky, C.-L.; Pernet, F.
10.1101/2021.02.08.429829 — ecology — Posted on 2021-02-10
2852 Single-cell ATAC and RNA sequencing reveal pre-existing and persistent subpopulations of cells associated with relapse of prostate cancer
Taavitsainen, S.; Engedal, N.; Cao, S.; Handle, F.; Prekovic, S.; Wetterskog, D.; Vuorinen, E. M.; Kiviaho, A.; Nätkin, R.; Devlies, W.; Henttinen, S.; Kaarijärvi, R.; Lahnalampi, M.; Kaljunen, H.; Nowakowska, K.; Syvälä, H.; Bläuer, M.; Cremaschi, P.; Claessens, F.; Visakorpi, T.; Tammela, T. L.; Murtola, T.; Granberg, K. J.; Ketola, K.; Mills, I. G.; Attard, G.; Wang, W.; Nykter, M.; Urbanucci, A.
10.1101/2021.02.09.430114 — cancer biology — Posted on 2021-02-10
2857 Integrated Collection of Stem Cell Bank data, a data portal for standardized stem cell information
Chen, Y.; Sakurai, K.; Maeda, S.; Masui, T.; Okano, H.; Dewender, J.; Seltmann, S.; Kurtz, A.; Masuya, H.; Nakamura, Y.; Sheldon, M.; Schneider, J.; Stacey, G.; Panina, Y.; Fujibuchi, W.
10.1101/2020.08.26.263830 — bioinformatics — Posted on 2021-02-10
2859 Chloroplast redox state changes indicate cell-to-cell signalling during the hypersensitive response
Lukan, T.; Zupanic, A.; Mahkovec Povalej, T.; Brunkard, J. O.; Jutersek, M.; Baebler, S.; Gruden, K.
10.1101/2021.02.08.430316 — plant biology — Posted on 2021-02-09
2860 Motor Sequences - Separating The Sequence From The Motor. A longitudinal rsfMRI Study
Jaeger, A.-T. P.; Huntenburg, J. M.; Tremblay, S. A.; Schneider, U.; Grahl, S.; Huck, J.; Tardif, C. L.; Villringer, A.; Gauthier, C. J.; Bazin, P.-L.; Steele, C. J.
10.1101/2021.02.09.430495 — neuroscience — Posted on 2021-02-09
2861 Neuronal morphology and physiology, functional brain networks and memory in temporal lobe epilepsy
Douw, L.; Nissen, I. A.; Fitzsimmons, S. M.; Santos, F. A.; Hillebrand, A.; van Straaten, E. C.; Stam, C. J.; de Witt Hamer, P. C.; Baayen, J. C.; Klein, M.; Reijneveld, J. C.; Heyer, D. B.; Verhoog, M. B.; Wilbers, R.; Hunt, S.; Mansvelder, H. D.; Geurts, J. J.; de Kock, C. P.; Goriounova, N. A.
10.1101/2021.01.31.428369 — neuroscience — Posted on 2021-02-10
2863 Streptococcus pyogenes forms serotype and local environment-dependent inter-species protein complexes
Chowdhury, S.; Khakzad, H.; Bergdahl, G. E.; Lood, R.; Ekstrom, S.; Linke, D.; Malmström, L.; Happonen, L.; Malmström, j.
10.1101/2021.02.09.430411 — microbiology — Posted on 2021-02-09
2864 High expression of CD38 and MHC class II on CD8+ T cells during severe influenza disease reflects bystander activation and trogocytosis
Jia, X.; Chua, B.; Loh, L.; Koutsakos, M.; Kedzierski, L.; Olshanski, M.; Heath, W.; Xu, J.; Wang, Z.; Kedzierska, K.
10.1101/2021.02.09.430410 — immunology — Posted on 2021-02-09
2865 Linking Labs: Interconnecting Experimental Environments
Schultz, T.; Putze, F.; Fehr, T.; Meier, M.; Mason, C.; Ahrens, F.; Herrmann, M.
10.1101/2021.02.09.430407 — neuroscience — Posted on 2021-02-09
2871 Checkpoint proteins in patients with precancer and cervical cancer
Kayukova, E. V.; Sholokhov, L. F.; Belokrinitskaya, T.; Tereshkov, P. P.; Kayukova Elena,
10.1101/2021.02.09.430409 — cancer biology — Posted on 2021-02-09
2873 Reduction of insulin/IGF-1 receptor rejuvenates immunity via positive feedback circuit
Lee, Y.; Jeong, D.-E.; Hwang, W.; Ham, S.; Park, H.-E.; Kwon, S.; Jung, Y.; Ashraf, J. M.; Murphy, C.; Lee, S.-J. V.
10.1101/795781 — genetics — Posted on 2021-02-09
2874 Yield Maintenance Under Drought is Orchestrated by the qDTY12.1-Encoded DECUSSATE Gene of Rice Through a Network With Other Flowering-Associated Genes Across the Genetic Background
de los Reyes, B. G.; Sanchez, J.; Pal Kaur, P.; Pabuayon, I. C. M.; Karampudi, N. B. R.; Kitazumi, A.; Sandhu, N.; Catolos, M.; Kumar, A.
10.1101/2021.02.09.430414 — genetics — Posted on 2021-02-09
2875 Improving germline transmission efficiency in chimeric chickens using a multi-stage injection approach
Naseri, D.; Dormiani, K.; Hajian, M.; Jafarpour, F.; Forouzanfar, M.; Karimi, N.; Nasr-Esfahani, M. H.
10.1101/2021.02.09.430408 — developmental biology — Posted on 2021-02-09
2876 Single cell transcriptomic analysis reveals cellular diversity of murine esophageal epithelium and age-associated mitochondrial dysfunction
Kabir, M. F.; Karami, A.; Cruz-Acuna, R.; Klochkova, A.; Saxena, R.; Mu, A.; Murray, M. G.; Keith, K.; Madzo, J.; Huang, H.; Jelinek, J.; Karakasheva, T.; Hamilton, K. E.; Muir, A. B.; Tetreault, M.-P.; Whelan, K. A.
10.1101/2021.02.08.430312 — molecular biology — Posted on 2021-02-09
2877 A refinement to gene editing in Atlantic salmon using asymmetrical oligonucleotide donors
Straume, A. H.; Kjaerner-Semb, E.; Skaftnesmo, K. O.; Güralp, H.; Lillico, S.; Wargelius, A.; Edvardsen, R. B.
10.1101/2021.02.08.430296 — molecular biology — Posted on 2021-02-09
2881 homeRNA: A self-sampling kit for the collection of peripheral blood and stabilization of RNA
Haack, A. J.; Lim, F. Y.; Kennedy, D. S.; Day, J. H.; Adams, K. N.; Lee, J. J.; Berthier, E.; Theberge, A. B.
10.1101/2021.02.08.430337 — bioengineering — Posted on 2021-02-09
2882 A Human 3D neural assembloid model for SARS-CoV-2 infection
Gleeson, J. G.; Wang, L.; Sievert, D.; Clark, A. E.; Federman, H.; Gastfriend, B. D.; Shusta, E.; Palecek, S.; Carlin, A.; Clark, A. E.
10.1101/2021.02.09.430349 — microbiology — Posted on 2021-02-09
2883 Intranasal type I interferon treatment is beneficial only when administered before clinical signs onset in the SARS-CoV-2 hamster model
Bessiere, P.; Wasniewsk, M.; Picard-Meyer, E.; Servat, A.; Figueroa, T.; Foret-Lucas, C.; Coggon, A.; Lesellier, S.; Boue, F.; Cebron, N.; Gausseres, B.; Trumel, C.; Foucras, G.; Salguero, F. J.; Monchatre-Leroy, E.; Volmer, R.
10.1101/2021.02.09.430458 — microbiology — Posted on 2021-02-09
2886 The protection of Gαz-null NOD mice from hyperglycemia is sexually dimorphic and only partially β-cell autonomous
Fenske, R. J.; Peter, D. C.; Wienkes, H. N.; Schaid, M. D.; Reuter, A.; Carbajal, K. A.; Kimple, M. E.
10.1101/2021.02.08.430304 — physiology — Posted on 2021-02-09
2887 Cryo-EM Structures of the N501Y SARS-CoV-2 Spike Protein in Complex with ACE2 and Two Potent Neutralizing Antibodies
Zhu, X.; Mannar, D.; Srivastava, S. S.; Berezuk, A.; Demers, J.-P.; Saville, J.; Leopold, K.; Li, W.; Dimitrov, D. S.; Tuttle, K.; Zhou, S.; Chittori, S.; Subramaniam, S.
10.1101/2021.01.11.426269 — biophysics — Posted on 2021-02-09
2890 Pkd1 mutation has no apparent effects on peroxisome structure or lipid metabolism
Terabayashi, T.; Menezes, L. F.; Zhou, F.; Cai, H.; Walter, P. J.; Garraffo, H. M.; Germino, G. G.
10.1101/2021.02.08.430145 — genetics — Posted on 2021-02-09
2893 Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons
Gowrishankar, S.; Lyons, L.; Rafiq, N. M.; Roczniak-Ferguson, A.; De Camilli, P.; Ferguson, S.
10.1101/2020.06.13.149443 — cell biology — Posted on 2021-02-09
2898 Transcriptome signature of cell viability predicts drug response and drug interaction for Tuberculosis
Srinivas, V.; Ruiz, R. A.; Pan, M.; Immanuel, S. R. C.; Peterson, E. J. R.; Baliga, N. S.
10.1101/2021.02.09.430468 — microbiology — Posted on 2021-02-09
2902 Disruption of nuclear architecture as a cause of COVID-19 induced anosmia
Zazhytska, M.; Kodra, A.; Hoagland, D. A.; Fullard, J.; Shayya, H. J.; Omer, A.; Firestein, S.; Gong, Q.; Canoll, P.; Goldman, J. E.; Roussos, P.; tenOever, B. R.; Overdevest, J. B.; Lomvardas, S.
10.1101/2021.02.09.430314 — neuroscience — Posted on 2021-02-09
2903 A unified model of amino acid homeostasis in mammalian cells
Gauthier-Coles, G.; Vennitti, J.; Zang, Z.; Comb, W. C.; Javed, K.; Broer, A.; Broer, S.
10.1101/2021.02.08.430327 — systems biology — Posted on 2021-02-09
2910 Nse5/6 inhibits the Smc5/6 ATPase to facilitate DNA substrate selection.
Taschner, M.; Basquin, J.; Steigenberger, B.; Schaefer, I.; Soh, Y.-M.; Basquin, C.; Lorentzen, E.; Raeschle, M.; Scheltema, R. A.; Gruber, S.
10.1101/2021.02.09.430422 — biochemistry — Posted on 2021-02-09
2912 An algal symbiont (Breviolum psygmophilum) responds more strongly to chronic high temperatures than its facultatively symbiotic coral host (Astrangia poculata)
Chan, A. N.; Gonzalez-Guerrero, L. A.; Iglesias-Prieto, R.; Burmester, E. M.; Rotjan, R. D.; Finnerty, J. R.; Baums, I. B.
10.1101/2021.02.08.430325 — ecology — Posted on 2021-02-09
2914 A Cas-BCAR3 co-regulatory circuit controls lamellipodia dynamics
Steenkiste, E. M.; Berndt, J. D.; Pilling, C.; Simpkins, C.; Cooper, J. A.
10.1101/2021.01.29.428899 — cell biology — Posted on 2021-02-09
2917 An adaptive compromise - Conflicting evolutionary pressures on arthropod borne Zika virus dinucleotide composition in mammalian hosts and mosquito vectors
Fros, J. J.; Visser, I.; Tang, B.; Yan, K.; Nakayama, E.; Visser, T. M.; Koenraadt, C. J. M.; van Oers, M. M.; Pijlman, G. P.; Suhrbier, A.; Simmonds, P.
10.1101/2021.02.09.430415 — microbiology — Posted on 2021-02-09
2918 Human monoclonal antibodies against Staphylococcus aureus surface antigens recognize in vitro biofilm and in vivo implant infections
de Vor, L.; van Dijk, B.; van Kessel, K. P.; Kavanaugh, J. S.; de Haas, C. J.; Aerts, P. C.; Viveen, M. C.; Boel, E. C.; Fluit, A. C.; Kwiecinski, J. M.; Krijger, G. C.; Ramakers, R. M.; Beekman, F. J.; Dadachova, E.; Lam, M. G.; Vogely, H. C.; van der Wal, B. C.; van Strijp, J. A.; Horswill, A. R.; Weinans, H.; Rooijakkers, S. H.
10.1101/2021.02.09.429966 — microbiology — Posted on 2021-02-09
2919 Novel gut pathobionts confound results in a widely used mouse model of human inflammatory disease
Forster, S. C.; Clare, S.; Beresford-Jones, B. S.; Harcourt, K.; Notley, G.; Stares, M.; Kumar, N.; Soderholm, A. T.; Adoum, A.; Wong, H.; Moron, B.; Brandt, C.; Dougan, G.; Adams, D. J.; Maloy, K. J.; Pedicord, V. A.; Lawley, T. D.
10.1101/2021.02.09.430393 — microbiology — Posted on 2021-02-09
2920 Structure and efflux mechanism of the yeast pleiotropic drug resistance transporter Pdr5
Harris, A.; Wagner, M.; Du, D.; Raschka, S.; Gohlke, H.; Smits, S. H. J.; Luisi, B. F.; Schmitt, L.
10.1101/2021.02.09.430491 — microbiology — Posted on 2021-02-09
2921 Differential impact of plant secondary metabolites on the soil microbiota
Schütz, V.; Frindte, K.; Cui, J.; Zhang, P.; Hacquard, S.; Schulze-Lefert, P.; Knief, C.; Schulz, M.; Dörmann, P.
10.1101/2021.02.09.430398 — microbiology — Posted on 2021-02-09
2922 Avian influenza A viruses reassort and diversify differently in mallards and mammals
Ganti, K.; Bagga, A.; DaSilva, J.; Shepard, S. S.; Barnes, J. R.; Shriner, S. A.; Koelle, K.; Lowen, A. C.
10.1101/2021.02.08.430042 — microbiology — Posted on 2021-02-09
2923 Soil, senescence and exudate utilisation: Characterisation of the Paragon var. spring bread wheat root microbiome
Prudence, S. M. M.; Newitt, J. T.; Worsley, S. F.; Macey, M. C.; Murrell, J. C.; Lehtovirta-Morley, L.; Hutchings, M. I.
10.1101/2021.02.09.430461 — microbiology — Posted on 2021-02-09
2925 SARS-CoV-2 RBD-Tetanus toxoid conjugate vaccine induces a strong neutralizing immunity in preclinical studies
Valdes-Balbin, Y.; Santana-Mederos, D.; Quintero, L.; Fernandez, S.; Rodriguez, L.; Sanchez-Ramirez, B.; Perez, R.; Acosta, C.; Mendez, Y.; Ricardo, M. G.; Hernandez, T.; Bergado, G.; Pi, F.; Valdes, A.; Ramirez, U.; Oliva, R.; Soubal, J.-P.; Garrido, R.; Cardoso, F.; Landys, M.; Farinas, M.; Gonzalez, H.; Enriquez, J.; Noa, E.; Suarez, A.; Fang, C.; Espinosa, L. A.; Ramos, Y.; Gonzalez, L. J.; Climent, Y.; Rojas, G.; Relova-Hernandez, E.; Cabrera, Y.; Losada, S. L.; Boggiano, T.; Ojito, E.; Leon-Monzon, K.; Chiodo, F.; Paquet, F.; Chen, G.; Rivera, D. G.; Garcia-Rivera, D.; Verez-Bencomo, V.
10.1101/2021.02.08.430146 — immunology — Posted on 2021-02-09
2931 Energetic and structural features of SARS-CoV-2 N-protein co-assemblies with nucleic acids
Zhao, H.; Wu, D.; Nguyen, A.; Li, Y.; Adão, R.; Valkov, E.; Patterson, G. H.; Piszczek, G.; Schuck, P.
10.1101/2021.02.08.430344 — biophysics — Posted on 2021-02-09
2936 Automatic inference of demographic parameters using Generative Adversarial Networks
Wang, Z.; Wang, J.; Kourakos, M.; Hoang, N.; Lee, H. H.; Mathieson, I.; Mathieson, S.
10.1101/2020.08.05.237834 — genomics — Posted on 2021-02-09
2937 High Throughput Nanopore Sequencing of SARS-CoV-2 Viral Genomes from Patient Samples
Pater, A. A.; Bosmeny, M. S.; Parasrampuria, M.; Eddington, S. B.; Ovington, K. N.; Barkau, C. L.; White, A. A.; Metz, P. E.; Sylvain, R. J.; Chilamkurthy, R.; Yinusa, A. O.; Benzinger, S. W.; Hebert, M. M.; Gagnon, K. T.
10.1101/2021.02.09.430478 — genomics — Posted on 2021-02-09
2938 Using target capture to address conservation challenges: population-level tracking of a globally-traded herbal medicine
Manzanilla, V.; Teixidor Toneu, I.; Martin, G.; Hollingsworth, P.; de Boer, H. J.; Kool, A.
10.1101/744318 — genomics — Posted on 2021-02-09
2940 Phenotypic plasticity explains apparent reverse evolution of fat synthesis in parasitoid insects
Visser, B.; Alborn, H. T.; Rondeaux, S.; Haillot, M.; Hance, T.; Rebar, D.; Riederer, J. M.; Tiso, S.; van Eldijk, T. J. B.; Weissing, F. J.; Nieberding, C. M.
10.1101/2020.07.17.208876 — evolutionary biology — Posted on 2021-02-09
2944 A potent bispecific nanobody protects hACE2 mice against SARS-CoV-2 infection via intranasal administration
Wu, X.; Cheng, L.; Fu, M.; Huang, B.; Zhu, L.; Xu, S.; Shi, H.; Zhang, D.; Yuan, H.; Nawaz, W.; Yang, P.; Hu, Q.; Liu, Y.; Wu, Z.
10.1101/2021.02.08.429275 — microbiology — Posted on 2021-02-09
2945 The co-stimulatory activity of Tim-3 requires Akt and MAPK signaling and immune synapse recruitment
Kataoka, S.; Manandhar, P.; Lee, J.; Workman, C. J.; Banerjee, H.; Szymczak-Workman, A. L.; Kvorjak, M.; Lohmueller, J.; Kane, L. P.
10.1101/2019.12.30.878520 — immunology — Posted on 2021-02-09
2949 Direct imaging of anthrax intoxication in animals reveals shared and individual functions of CMG-2 and TEM-8 in cellular toxin entry
Merritt, C.; Chun, E. M.; Fattah, R. J.; Moayeri, M.; Paliga, D.; Neumann, S.; Heumann, R.; Leppla, S. H.; Bugge, T. H.
10.1101/2021.01.22.427304 — pathology — Posted on 2021-02-09
2950 RNA matchmaking remodels lncRNA structure and promotes PRC2 activity
Balas, M. M.; Hartwick, E. W.; Barrington, C.; Roberts, J. T.; Wu, S. K.; Bettcher, R.; Griffin, A. M.; Kieft, J. S.; Johnson, A. M.
10.1101/2020.04.13.040071 — biochemistry — Posted on 2021-02-09
2951 Inferring linguistic transmission between generations at the scale of individuals
Thouzeau, V.; Affholder, A.; Mennecier, P.; Verdu, P.; Austerlitz, F.
10.1101/441246 — bioinformatics — Posted on 2021-02-09
2952 Rcn3 is Involved in Postnatal Tendon Development by Regulating Collagen Modification and Fibrillogenesis
Park, N. R.; Shetye, S.; Keene, D. R.; Tufa, S.; Hudson, D. M.; Archer, M.; Soslowsky, L. J.; Dyment, N. A.; Joeng, K. S.
10.1101/2020.09.25.313098 — developmental biology — Posted on 2021-02-09
2953 Recurrent emergence and transmission of a SARS-CoV-2 Spike deletion H69/V70
Kemp, S.; Meng, B.; Ferreira, I.; Datir, R.; Harvey, W.; Collier, D.; COVID-19 Genomics UK (COG-UK) consortium, ; Papa, G.; Carabelii, A.; Lytras, S.; Kenyon, J.; Lever, A.; James, L.; Robertson, D. L.; Gupta, R. K.
10.1101/2020.12.14.422555 — microbiology — Posted on 2021-02-09
2955 SARS-CoV-2 RBD219-N1C1: A Yeast-Expressed SARS-CoV-2 Recombinant Receptor-Binding Domain Candidate Vaccine Stimulates Virus Neutralizing Antibodies and T-cell Immunity in Mice
Pollet, J.; Chen, W.-H.; Versteeg, L.; Keegan, B.; Zhan, B.; Wei, J.; Liu, Z.; Lee, J.; Kundu, R.; Adhikari, R.; Poveda, C.; Villar Mondragon, M. J.; de Araujo Leao, A. C.; Altieri Rivera, J.; Momin, Z.; Gillespie, P. M.; Kimata, J.; Strych, U.; Hotez, P. J.; Bottazzi, M. E.
10.1101/2020.11.04.367359 — immunology — Posted on 2021-02-09
2959 Graded recruitment of pupil-linked neuromodulation by parametric stimulation of the vagus nerve
Mridha, Z.; de Gee, J. W.; Shi, Y.; Alkashgari, R.; Williams, J.; Suminski, A.; Ward, M. P.; Zhang, W.; McGinley, M. J.
10.1101/2019.12.28.890111 — neuroscience — Posted on 2021-02-09
2963 Tankyrase-mediated ADP-ribosylation is a novel regulator of TNF-induced death
Liu, L.; Sandow, J. J.; Leslie Pedrioli, D. M.; Silke, N.; Hu, Z.; Morrish, E.; Chau, D.; Kratina, T.; Kueh, A. J. M.; Hottiger, M. O.; Webb, A. I.; Lalaoui, N.; Silke, J.
10.1101/2021.02.09.430424 — cell biology — Posted on 2021-02-09
2966 Role of T cells in intrauterine administration of activated peripheral blood mononuclear cells in recurrent implantation failure.
Ricaud, G.; Vaillancourt, C.; Blais, V.; Disdier, M.; Joao, F.; Johnson, B.; Benkhalifa, M.; Miron, P.; Bernier, J.
10.1101/2021.01.06.425452 — immunology — Posted on 2021-02-09
2969 Quantitative proteomics identifies secreted diagnostic biomarkers as well as tumor-dependent prognostic targets for clear cell Renal Cell Carcinoma
Senturk, A.; Sahin, A. T.; Armutlu, A.; Kiremit, M. C.; Acar, O.; Erdem, S.; Bagbudar, S.; Esen, T.; Tuncbag, N.; Ozlu, N.
10.1101/2021.02.08.430238 — cancer biology — Posted on 2021-02-09
2974 Wavelength-dependent effects of artificial light at night on phytoplankton growth and community structure
Diamantopoulou, C.; Christoforou, E.; Dominoni, D. M.; Kaiserli, E.; Czyzewski, J.; Mirzai, N.; Spatharis, S.
10.1101/2021.02.08.430211 — ecology — Posted on 2021-02-09
2975 Ciliary control of meiotic chromosomal pairing mechanics and germ cell morphogenesis
Mytlis, A.; Kumar, V.; Tao, Q.; Deis, R.; Levy, K.; Masek, M.; Eitan, H.; Nather, F.; Shawahny, A.; Bachmann-Gagescu, R.; Roy, S.; Elkouby, Y. M.
10.1101/2021.02.08.430249 — cell biology — Posted on 2021-02-09
2979 Male pheromones modulate synaptic transmission at the C. elegans neuromuscular junction in a sexually dimorphic manner
Qian, K.-Y.; Zeng, W.-X.; Hao, Y.; Zeng, X.-T.; Liu, H.; Li, L.; Chen, L.; Tian, F.-M.; Chang, C.; Hall, Q.; Song, C.-X.; Gao, S.; Hu, Z.; Kaplan, J.; Li, Q.; Tong, X.-J.
10.1101/2021.02.09.430459 — neuroscience — Posted on 2021-02-09
2982 Methylomic alteration in peripheral blood lymphocytes of prodromal stage and first-episode Chinese Han schizophrenia patients
Liu, Y.; Lang, B.; Smith, R. C.; Wang, G.; Wang, J.; Liu, Y.; Jin, H.; Lyu, H.; Davis, J. M.; Guidotti, A. R.; Zhao, J.; Wu, R.
10.1101/2021.02.07.430160 — genetics — Posted on 2021-02-09
2983 Modeling features of addiction with an oral oxycodone self-administration paradigm
Murphy, C.; Chang, Y.-H.; Pareta, R.; Li, J.-N.; Earnest, T.; Tooley, J. R.; Vachez, Y. M.; Gereau, R.; Copits, B. A.; Kravitz, A. V.; Creed, M. C.
10.1101/2021.02.08.430180 — neuroscience — Posted on 2021-02-09
2985 RNA fragment assembly with experimental restraints
Chojnowski, G.; Zaborowski, R.; Magnus, M.; Bujnicki, J. M.
10.1101/2021.02.08.430198 — bioinformatics — Posted on 2021-02-09
2986 Copy number variation profile-based genomic subtyping of premenstrual dysphoric disorder in Chinese
Xue, H.; Wu, Z.; Long, X.; Ullah, A.; Chen, S.; Mat, W.-K.; Sun, P.; Gao, M.-Z.; Wang, J.-Q.; Wang, H.-J.; Li, X.; Sun, W.-J.; Qiao, M.-Q.
10.1101/2021.02.08.430168 — genomics — Posted on 2021-02-09
2990 Maternal obesity programs white and brown adipose tissue transcriptome and lipidome in offspring in a sex-dependent manner
Savva, C.; Helguero, L.; Gonzalez-Garnillo, M.; Melo, T.; couto, d.; Buyandelger, B.; Gustafsson, S.; Liu, J.; Domingues, M. R.; Li, X.; Korach-Andre, M.
10.1101/2021.02.08.430188 — cell biology — Posted on 2021-02-09
2994 On the Gestural Origin of Language Lateralisation: Manual Communication reflects Broca's Asymmetry in Monkeys
Becker, Y.; Margiotoudi, K.; Marie, D.; Roth, M.; Nazarian, B.; Lacoste, R.; Anton, J.-L.; Coulon, O.; Claidiere, N.; Meguerditchian, A.
10.1101/2021.02.09.430276 — neuroscience — Posted on 2021-02-09
2998 The anterior Hox gene ceh-13 and elt-1/GATA activate the posterior Hox genes nob-1 and php-3 to specify posterior lineages in the C. elegans embryo
Murray, J. I.; Preston, E.; Crawford, J. P.; Rumley, J. D.; Amom, P.; Anderson, B. D.; Sivaramakrishnan, P.; Patel, S. D.; Bennett, B. A.; Lavon, T. D.; Peng, F.; Zacharias, A. L.
10.1101/2021.02.09.430385 — genetics — Posted on 2021-02-09
2999 Pkd1 mutation has no apparent effects on peroxisome structure or lipid metabolism
Terabayashi, T.; Menezes, L. F.; Zhou, F.; Cai, H.; Walter, P. J.; Garraffo, H. M.; Germino, G. G.
10.1101/2021.02.08.430145 — genetics — Posted on 2021-02-09
3000 Investigating receptor-mediated antibody transcytosis using blood-brain barrier organoid arrays
Simonneau, C.; Duschmalé, M.; Gavrilov, A.; Brandenberg, N.; Hoehnel, S.; Ceroni, C.; Lasalle, E.; Knoetgen, H.; Niewoehner, J.; Villaseñor, R.
10.1101/2021.02.09.430382 — cell biology — Posted on 2021-02-09
3001 Deciphering 3D Human Sphygmopalpation Pulse Patterns using "X-ray" Images Acquired from Tactile Robotic Fingers
KONG, K. W.; CHAN, H.-y.; XIE, J.; LEE, F. C. S.; LEUNG, A. Y. L.; GUAN, B.; SHEN, J.; TAAM WONG, V. C.-W.; LI, W. J.
10.1101/2021.01.10.426152 — bioengineering — Posted on 2021-02-09
3003 Climate, latitude, and land cover predict flying insect biomass across a German malaise trap network
Welti, E. A. R.; Zajicek, P.; Ayasse, M.; Bornholdt, T.; Buse, J.; Dziock, F.; Engelmann, R. A.; Englmeier, J.; Fellendorf, M.; Foerschler, M. I.; Frenzel, M.; Fricke, U.; Ganuza, C.; Hippke, M.; Hoenselaar, G.; Kaus-Thiel, A.; Mandery, K.; Marten, A.; Monaghan, M. T.; Morkel, C.; Muller, J.; Puffpaff, S.; Redlich, S.; Richter, R.; Rojas Botero, S.; Scharnweber, T.; Scheiffarth, G.; Schmidt Yanez, P.; Schumann, R.; Seibold, S.; Steffan-Dewenter, I.; Stoll, S.; Tobisch, C.; Twietmeyer, S.; Uhler, J.; Vogt, J.; Weis, D.; Weisser, W. W.; Wilmking, M.; Haase, P.
10.1101/2021.02.02.429363 — ecology — Posted on 2021-02-09
3004 AF10 (MLLT10) prevents somatic cell reprogramming through regulation of H3K79 methylation
Ugurlu-Cimen, D.; Odluyurt, D.; Sevinc, K.; Ozkan-Kucuk, N. E.; Ozcimen, B.; Demirtas, D.; Enustun, E.; Aztekin, C.; Philpott, M.; Oppermann, U.; Ozlu, N.; Onder, T. T.
10.1101/2020.12.22.423908 — developmental biology — Posted on 2021-02-09
3006 Functional ultrasound imaging of the spreading activity following optogenetic stimulation of the rat visual cortex
Provansal, M.; Labernede, G.; Joffrois, C.; Rizkallah, A.; Goulet, R.; Valet, M.; Deschamps, W.; Ferrari, U.; Chaffiol, A.; Dalkara, D.; Sahel, J.-A.; Tanter, M.; Picaud, S.; Gauvain, G.; Arcizet, F.
10.1101/2021.02.05.429985 — neuroscience — Posted on 2021-02-09
3010 Phenotyping the preterm brain: characterising individual deviations from normative volumetric development in two large infant cohorts
Dimitrova, R.; Arulkumaran, S.; Carney, O.; Chew, A.; Falconer, S.; Ciarrusta, J.; Wolfers, T.; Batalle, D.; Cordero-Grande, L.; Price, A. N.; Teixeira, R. P.; Hughes, E.; Egloff, A.; Hutter, J.; Makropoulos, A.; Robinson, E. C.; Schuh, A.; Vecchiato, K.; Steinweg, J. K.; Macleod, R.; Marquand, A. F.; McAlonan, G.; Rutherford, M. A.; Counsell, S. J.; Smith, S. M.; Rueckert, D.; Hajnal, J. V.; O'Muircheartaigh, J.; Edwards, A. D.
10.1101/2020.08.05.228700 — neuroscience — Posted on 2021-02-09
3011 Patients with ventromedial prefrontal lesions show an implicit approach bias to angry faces
Buades-Rotger, M.; Solbakk, A.-K.; Liebrand, M.; Endestad, T.; Funderud, I.; Siegwardt, P.; Enter, D.; Roelofs, K.; Kraemer, U. M.
10.1101/2020.06.21.162628 — neuroscience — Posted on 2021-02-09
3012 Mapping Transcriptomic Vector Fields of Single Cells
Qiu, X.; Zhang, Y.; Hosseinzadeh, S.; Yang, D.; Pogson, A. N.; Wang, L.; Shurtleff, M.; Yuan, R.; Xu, S.; Ma, Y.; Replogle, J.; Darmanis, S.; Xing, J.; Weissman, J.
10.1101/696724 — systems biology — Posted on 2021-02-09
3015 Biologically excretable AIE dots for visualizing through the marmosets intravitally: horizons in future clinical nanomedicine
Feng, Z.; Bai, S.; Qi, J.; Sun, C.; Zhang, Y.; Yu, X.; Ni, H.; Wu, D.; Fan, X.; Xue, D.; Liu, S.; Chen, M.; Gong, J.; Wei, P.; He, M.; Lam, J. W. Y.; Li, X.; Tang, B. Z.; Gao, L.; Qian, J.
10.1101/2020.05.26.113316 — bioengineering — Posted on 2021-02-09
3016 Enhanced genetic analysis of type 1 diabetes by selecting variants on both effect size and significance, and by integration with autoimmune thyroid disease
Crouch, D. J. M.; Inshaw, J. R. J.; Robertson, C. C.; Zhang, J.-Y.; Chen, W.-M.; Onengut-Gumuscu, S.; Cutler, A. J.; Sidore, C.; Cucca, F.; Pociot, F.; Concannon, P.; Rich, S. S.; Todd, J. A.
10.1101/2021.02.05.429962 — genetics — Posted on 2021-02-09
3017 Signatures of mito-nuclear coevolution in a warbler species complex
Wang, S.; Ore, M.; Mikkelsen, E. K.; Lee-Yaw, J.; Toews, D. P. L.; Rohwer, S.; Irwin, D. E.
10.1101/2020.04.06.028506 — evolutionary biology — Posted on 2021-02-09
3018 5-Azacytidine: Effects on the Expression of alpha-Cardiac Actin in Pericytes from Human Adipose Tissue
Ferrreira-Silva, V.; Baqui, M. M.; de Molfetta, G. A.; Fontes, A. M.; Zanette, D. L.; Ferreira, F. U.; Orellana, M. D.; Silva, W. A.; Covas, D. T.
10.1101/2021.02.08.430216 — cell biology — Posted on 2021-02-08
3019 Whole genome 6-methyladenosine sequencing (6-mA-Seq) enables bacterial epigenomics studies.
Spurbeck, R. R.; Minard-Smith, A. T.; Catlin, L. A.; Murdoch, R. W.; Chou, R. M.; Albrecht, K. M.
10.1101/2021.02.08.430217 — genomics — Posted on 2021-02-08
3022 Simultaneous functional MRI of socially interacting marmosets
Gilbert, K. M.; Clery, J. C.; Gati, J. S.; Hori, Y.; Mashkovtsev, A.; Zeman, P.; Menon, R. S.; Schaeffer, D. J.; Everling, S.
10.1101/2021.02.08.430294 — neuroscience — Posted on 2021-02-08
3023 Rare long-range cortical connections enhance information processing
Deco, G.; Sanz Perl, Y.; Vuust, P.; Tagliazucchi, E.; Kennedy, H.; Kringelbach, M. L.
10.1101/2021.02.08.430236 — neuroscience — Posted on 2021-02-08
3031 Physiological underpinning of default-mode network emergence in the human infant brain
Yu, Q.; Ouyang, M.; Detre, J. A.; Kang, H.; Hu, D.; Hong, B.; Fang, F.; Peng, Y.; Huang, H.
10.1101/2021.02.08.430158 — neuroscience — Posted on 2021-02-08
3032 Structure of the human SAGA coactivator complex
Nogales, E.; Herbst, D.; Esbin, M.; Louder, R. K.; Dugast-Darzacq, C.; Dailey, G.; Fang, Q.; Darzacq, X.; Tjian, R.
10.1101/2021.02.08.430339 — biophysics — Posted on 2021-02-08
3033 Interpreting machine learning models to investigate circadian regulation and facilitate exploration of clock function
Gardiner, L.-J.; Rusholme-Pilcher, R.; Colmer, J.; Rees, H.; Crescente, J. M.; Carrieri, A. P.; Duncan, S.; Pyzer-Knapp, E. O.; Krishna, R.; Hall, A.
10.1101/2021.02.04.429826 — genomics — Posted on 2021-02-08
3034 POPULATION GENOMIC ANALYSIS OF CRYPTOCOCCUS BRAZILIAN STRAINS REVEALS AN AFRICAN TYPE SUBCLADES DISTRIBUTION
Maufrais, C.; de Oliveira, L.; Bastos, R. W.; Moyrand, F.; Reis, F. C.; Valero, C.; Gimenez, B.; Josefowicz, L. J.; Goldman, G. H.; Rodrigues, M. L.; Janbon, G.
10.1101/2021.02.08.430197 — genomics — Posted on 2021-02-08
3035 celldeath: a tool for detection of cell death in transmitted light microscopy images by deep learning-based visual recognition
La Greca, A.; Perez, N.; Castaneda, S.; Milone, P. M.; Scarafia, M. A.; Möbbs, A. M.; Waisman, A.; Moro, L. N.; Sevlever, G.; Luzzani, C.; Miriuka, S. G.
10.1101/2020.03.22.002253 — cell biology — Posted on 2021-02-08
3036 Separation and enrichment of sodium-motile bacteria using cost-effective microfluidics.
Gurung, J. P.; Navvab Kashani, M.; Agarwal, S.; Peralta, G.; Gel, M.; Baker, M. A.
10.1101/2020.11.24.395772 — microbiology — Posted on 2021-02-08
3039 Inferring the heritability of large-scale functional networks with a multivariate ACE modeling approach
Ribeiro, F. L.; dos Santos, F. R. C.; Sato, J. R.; Pinaya, W. H. L.; Biazoli Junior, C. E.
10.1101/437335 — neuroscience — Posted on 2021-02-08
3040 Contrasting recruitment of skin-associated adipose depots during cold challenge of mouse and human
Kasza, I.; Kuehn, J.-P.; Volzke, H.; Hernando, D.; Xu, Y. G.; Siebert, J. W.; Gibson, A. L.; Yen, C.-L. E.; Nelson, D. W.; MacDougald, O. A.; Richardson, N. E.; Lamming, D.; Kern, P. A.; Alexander, C.
10.1101/2020.09.16.300533 — physiology — Posted on 2021-02-08
3042 Neuroblastoma formation requires unconventional CD4 T cells and myeloid amino acid metabolism
Van de Velde, L.-A.; Allen, E. K.; Crawford, J. C.; Wilson, T. L.; Guy, C. S.; Russier, M.; Zeitler, L.; Bahrami, A.; Finkelstein, D.; Pelletier, S.; Schultz-Cherry, S.; Thomas, P. G.; Murray, P. J.
10.1101/2021.02.08.430292 — cancer biology — Posted on 2021-02-08
3045 O-GlcNAc regulates MTA1 transcriptional activity during breast cancer cells genotoxic adaptation
Xie, X.; Wu, Q.; Zhang, K.; Liu, Y.; Zhang, N.; Chen, Q.; Wang, L.; Li, W.; Zhang, J.; Liu, Y.
10.1101/2021.02.08.430201 — biochemistry — Posted on 2021-02-08
3047 Social network architecture and the tempo of cumulative cultural evolution
Cantor, M.; Chimento, M.; Smeele, S. Q.; He, P.; Papageorgiou, D.; Aplin, L. M.; Farine, D. R.
10.1101/2020.12.04.411934 — evolutionary biology — Posted on 2021-02-08
3050 Altered TGFB1 regulated pathways promote accelerated tendon healing in the superhealer MRL/MpJ mouse
Kallenbach, J.; Freeberg, M.; Abplanalp, D.; Lillis, J.; Ashton, J.; Loiselle, A. E.; Buckley, M.; van Wijnen, A.; Awad, H. A.
10.1101/2021.02.08.430308 — cell biology — Posted on 2021-02-08
3052 Visualizing endogenous RhoA activity with an improved localization-based, genetically encoded biosensor
Mahlandt, E. K.; Arts, J. J. G.; van der Meer, W. J.; van der Linden, F. H.; Tol, S.; van Buul, J. D.; Gadella, T. W. J.; Goedhart, J.
10.1101/2021.02.08.430250 — cell biology — Posted on 2021-02-08
3054 Architecture of cell-cell junctions in situ reveals a mechanism for bacterial biofilm inhibition
Melia, C.; Bolla, J. R.; Katharios-Lanwermeyer, S.; Mihaylov, D.; Hoffmann, P.; Huo, J.; Wozny, M.; Elfari, L.; Boehning, J.; Owens, R.; Robinson, C. V.; O'Toole, G.; Bharat, T.
10.1101/2021.02.08.430230 — microbiology — Posted on 2021-02-08
3056 The envelope cytoplasmic tail regulates HIV-1 assembly and spread
Snetkov, X.; Haider, T.; Mesner, D.; Groves, N.; Van Engeleburg, S.; Jolly, C.
10.1101/2021.02.08.430194 — microbiology — Posted on 2021-02-08
3057 Ribonucleotide reductase, a novel target for gonorrhea
Narasimhan, J.; Letinski, S.; Jung, S.; Gerasyuto, A.; Wang, J.; Arnold, M.; Chen, G.; Hedrick, J.; Dumble, M.; Ravichandran, K.; Levitz, T.; Cui, C.; Drennan, C. L.; Stubbe, J.; Karp, G.; Branstrom, A.
10.1101/2020.11.19.389957 — microbiology — Posted on 2021-02-08
3061 Efficacy of CDK4/6 inhibitors in preclinical models of malignant pleural mesothelioma
Aliagas, E.; Alay, A.; Martinez-Iniesta, M.; Hernandez-Madrigal, M.; Cordero, D.; Gausachs, M.; Pros, E.; Saigi, M.; Busacca, S.; Sharkley, A.; Dawson, A.; Palmero, R.; Padrones, S.; Aso, S.; Escobar, I.; Ramos, R.; Llatjos, R.; Vidal, A.; Varela, M.; Sanchez-Cespedes, M.; Fennell, D.; Munoz-Pinedo, C.; Villanueva, A.; Sole, X.; Nadal, E.
10.1101/2021.02.08.430196 — cancer biology — Posted on 2021-02-08
3065 A Generative Approach toward Precision Antimicrobial Peptide Design
Ferrell, J. B.; Remington, J. M.; Van Oort, C. M.; Sharafi, M.; Aboushousha, R.; Janssen-Heininger, Y.; Schneebeli, S. T.; Wargo, M. J.; Wshah, S.; Li, J.
10.1101/2020.10.02.324087 — biophysics — Posted on 2021-02-08
3070 Automatic Landmark Detection of Human Back Surface from Depth Images via Deep Learning
Delgarmi, M.; Heravi, H.; Rahimpour Jounghani, A.; Shahrezie, A.; Ebrahimi, A.; Shamsi, M.
10.1101/2021.02.04.429842 — bioengineering — Posted on 2021-02-08
3071 Plasticity in novel environments induces larger changes in genetic variance than adaptive divergence
Walter, G. M.; Terranova, D.; Clark, J.; Cozzolino, S.; Cristaudo, A.; Hiscock, S. J.; Bridle, J. R.
10.1101/2021.02.08.430333 — evolutionary biology — Posted on 2021-02-08
3072 The epigenetic eraser LSD1 lies at the apex of a reversible erythroid to myeloid cell fate decision
Yu, L.; Myers, G.; Ku, C.-J.; Schneider, E.; Wang, Y.; Singh, S.; Jearawiriyapaisarn, N.; White, A.; Moriguchi, T.; Khoriaty, R.; Yamamoto, M.; Rosenfeld, M. G.; Pedron, J.; Bushweller, J. H.; Lim, K.-C.; Engel, J. D.
10.1101/2021.01.13.426552 — developmental biology — Posted on 2021-02-08
3074 TAEL 2.0: An Improved Optogenetic Expression System for Zebrafish
LaBelle, J.; Ramos-Martinez, A.; Shen, K.; Motta-Mena, L. B.; Gardner, K. H.; Materna, S. C.; Woo, S.
10.1101/2020.09.24.312470 — developmental biology — Posted on 2021-02-08
3075 The CIP2A-TOPBP1 complex safeguards chromosomal stability during mitosis
De Marco Zompit, M.; Mooser, C.; Adam, S.; Rossi, S. E.; Jeanrenaud, A.; Leimbacher, P.-A.; Fink, D.; Durocher, D.; Stucki, M.
10.1101/2021.02.08.430274 — cell biology — Posted on 2021-02-08
3076 Genome-wide CRISPR interference screen identifies long non-coding RNA loci required for differentiation and pluripotency
Haswell, J. R.; Mattioli, K.; Gerhardinger, C.; Maass, P. G.; Foster, D. J.; Fernandez, P. P.; Wang, X.; Rinn, J. L.; Slack, F. J.
10.1101/2021.02.08.430256 — molecular biology — Posted on 2021-02-08
3077 NEIL1 and NEIL2 DNA glycosylases regulate anxiety and learning in a cooperative manner
Hildrestrand, G. A.; Rolseth, V.; Kunath, N.; Suganthan, R.; Jensen, V.; Bugaj, A. M.; Fernandez-Berrocal, M. S.; Sikko, S. B.; Vetlesen, S.; Kusnierczyk, A.; Olsen, A.-K.; Guetzkow, K. B.; Rowe, A. D.; Wang, W.; Moldestad, O.; Syrstad, M. D.; Slupphaug, G.; Eide, L.; Klungland, A.; Saetrom, P.; Luna, L.; Ye, J.; Scheffler, K.; Bjoras, M.
10.1101/2021.02.08.430208 — molecular biology — Posted on 2021-02-08
3080 Protistan grazing impacts microbial communities and carbon cycling at deep-sea hydrothermal vents
Hu, S. K.; Herrera, E. L.; Smith, A. R.; Pachiadaki, M. G.; Edgcomb, V. P.; Sylva, S. P.; Chan, E. W.; Seewald, J. S.; German, C. R.; Huber, J. A.
10.1101/2021.02.08.430233 — microbiology — Posted on 2021-02-08
3081 Genetic models of latent tuberculosis in mice reveal differential control by innate and adaptive immunity
Su, H.; Lin, K.; Tiwari, D.; Healy, C.; Trujillo, C.; Liu, Y.; Schnappinger, D.; Ehrt, S.
10.1101/2021.02.08.430271 — microbiology — Posted on 2021-02-08
3084 Activin A correlates with the worst outcomes in COVID-19 patients, and can be induced by cytokines via the IKK/NF-kappa B pathway
McAleavy, M.; Zhang, Q.; Xu, J.; Pan, L.; Wakai, M.; Ehmann, P. J.; Wipperman, M. F.; Shavlakadze, T.; Hamon, S. C.; Boyapati, A.; Morton, L. G.; Kyratsous, C. A.; Glass, D. J.
10.1101/2021.02.04.429815 — immunology — Posted on 2021-02-08
3085 Fear in the mind's eye: Mental imagery can generate and regulate acquired differential fear conditioned reactivity
Greening, S. G.; Lee, T.-H.; Gregoire, L.; Burleigh, L.; Robinson, T.; Jiang, X.; Mather, M.; Kaplan, J.
10.1101/2021.02.04.429795 — neuroscience — Posted on 2021-02-08
3088 Developmental and behavioral phenotypes in a new mouse model of DDX3X syndrome
Boitnott, A.; Ung, D.; Garcia-Forn, M.; Niblo, K.; Mendonca, D.; Flores, M.; Maxwell, S.; Ellegood, J.; Qiu, L. R.; Grice, D. E.; Lerch, J. P.; Rasin, M.-R.; Buxbaum, J. D.; Drapeau, E.; De Rubeis, S.
10.1101/2021.01.22.427482 — neuroscience — Posted on 2021-02-08
3090 Using induced pluripotent stem cells to investigate human neuronal phenotypes in 1q21.1 deletion and duplication syndrome.
Chapman, G.; Alsaqati, M.; Lunn, S.; Singh, T.; Linden, S. C.; Linden, D. E. J.; van den Bree, M. B.; Ziller, M.; Owen, M.; Hall, J.; Harwood, A.; Syed, Y. A.
10.1101/2021.02.08.430246 — neuroscience — Posted on 2021-02-08
3091 Repression by the Arabidopsis TOPLESS corepressor requires association with the core Mediator complex
Leydon, A. R.; Wang, W.; Gala, H. P.; Gilmour, S.; Juarez-Solis, S.; Zemke, J. E.; Zahler, M. L.; Zheng, N.; Nemhauser, J. L.
10.1101/2020.03.04.976134 — plant biology — Posted on 2021-02-08
3093 CIP2A is a prime synthetic-lethal target for BRCA-mutated cancers
Adam, S.; Rossi, S. E.; Moatti, N.; De Marco Zompit, M.; Ng, T. F.; Alvarez-Quilon, A.; Desjardins, J.; Bhaskaran, V.; Martino, G.; Setiaputra, D.; Noordermeer, S. M.; Ohsumi, T. K.; Hustedt, N.; Szilard, R. K.; Chaudhary, N.; Munro, M.; Veloso, A.; Melo, H.; Yin, S. Y.; Papp, R.; Young, J. T. F.; Zinda, M.; Stucki, M.; Durocher, D.
10.1101/2021.02.08.430060 — cancer biology — Posted on 2021-02-08
3098 Mechanisms of GPCR hijacking by Staphylococcus aureus
Grison, C. M.; Leyrat, C.; Lambey, P.; Jeannot, S.; Del Nero, E.; Fontanel, S.; Peysson, F.; Heuninck, J.; Sounier, R.; Durroux, T.; Granier, S.; Bechara, C.
10.1101/2021.02.08.430206 — biochemistry — Posted on 2021-02-08
3099 Mobile Element Insertions and Associated Structural Variants in Longitudinal Breast Cancer Samples
Steely, C. J.; Russell, K. L.; Feusier, J. E.; Qiao, Y.; Tavtigian, S. V.; Marth, G.; Jorde, L. B.
10.1101/2020.02.10.942680 — genomics — Posted on 2021-02-08
3101 CHD4-NURD controls mouse neonate spermatogonia survival
de Castro, R. O.; Goitea, V.; Previato, L.; Carbajal, A.; Griffin, C.; Pezza, R.
10.1101/687137 — developmental biology — Posted on 2021-02-08
3103 FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in Bacillus subtilis cell division
Whitley, K. D.; Jukes, C.; Tregidgo, N.; Karinou, E.; Almada, P.; Henriques, R. D.; Dekker, C.; Holden, S.
10.1101/2020.07.01.182006 — microbiology — Posted on 2021-02-08
3104 Dendrimer-targeted immunosuppression of microglia reactivity super-accelerates photoreceptor regeneration in the zebrafish retina
Emmerich, K. B.; White, D. T.; Kambhampati, S. P.; Lee, G. Y.; Fu, T.-M.; Sahoo, A.; Saxena, M. T.; Betzig, E.; Kannan, R. M.; Mumm, J. S.
10.1101/2020.08.05.238352 — neuroscience — Posted on 2021-02-08
3107 Effect of using a physical assistance device for movements involving trunk bending
Jelti, Z.; Lebel, K.; Bastide, S.; Le Borgne, P.; Slangen, P.; Vignais, N.
10.1101/2021.02.08.429597 — physiology — Posted on 2021-02-08
3108 Acyl chain shortening induced by inhibition of acetyl-CoA carboxylase renders phosphatidylcholine redundant
Bao, X.; Koorengevel, M. C.; Groot Koerkamp, M. J. A.; Homavar, A.; Weijn, A.; Crielaard, S.; Renne, M. F.; Geerts, W. J. C.; Surma, M. A.; Mari, M.; Holstege, F. C. P.; Klose, C.; de Kroon, A. I. P. M.
10.1101/2021.02.08.429707 — biochemistry — Posted on 2021-02-08
3111 Pumilio protects Xbp1 mRNA from regulated Ire1-dependent decay
Cairrao, F.; Santos, C.; Le-Thomas, A.; Marsters, S.; Ashkenazi, A.; Domingos, P.
10.1101/2021.02.08.430300 — cell biology — Posted on 2021-02-08
3113 Global warming readiness: Feasibility of enhanced biological phosphorus removal from wastewater at 35oC
Qiu, G.; Law, Y.; Zuniga-Montanez, R.; Lu, Y.; Roy, S.; Thi, S. S.; Hoon, H. Y.; Nguyen, T. Q. N.; Eganathan, K.; Liu, X.; Nielsen, P. H.; Williams, R.; Wuertz, S.
10.1101/2021.02.08.429585 — microbiology — Posted on 2021-02-08
3117 Brain age relates to early life factors but not to accelerated brain aging
Vidal-Pineiro, D.; Wang, Y.; Krogsrud, S. K.; Amlien, I. K.; Baare, W. F.; Bartres-Faz, D.; Bertram, L.; Brandmaier, A. M.; Drevon, C. A.; Duzel, S.; Ebmeier, K. P.; Henson, R. N.; Junque, C.; Kievit, R.; Kuhn, S.; Leonardsen, E.; Lindenberger, U.; Madsen, K. S.; Magnussen, F.; Mowinckel, A. M.; Nyberg, L.; Roe, J. M.; Segura, B.; Sorensen, O.; Suri, S.; Zsoldos, E.; AIBL, ; Walhovd, K. B.; Fjell, A. M.
10.1101/2021.02.08.428915 — neuroscience — Posted on 2021-02-08
3118 Phellem translational landscape throughout secondary development in Arabidopsis roots
Leal, A. R.; Barros, P.; Parizot, B.; Sapeta, H.; Vangheluwe, N.; Andersen, T. G.; Beeckman, T.; Oliveira, M. M.
10.1101/2021.02.08.429142 — plant biology — Posted on 2021-02-08
3121 CAMAP: Artificial neural networks unveil the role of codon arrangement in modulating MHC-I peptides presentation
Daouda, T.; Dumont-Lagace, M.; Feghaly, A.; Benslimane, Y.; Panes, R.; Courcelles, M.; Benhammadi, M.; Harrington, L.; Thibault, P.; Major, F.; Bengio, Y.; Gagnon, E.; Lemieux, S.; Perreault, C.
10.1101/2020.06.03.078824 — bioinformatics — Posted on 2021-02-08
3123 Limiting the loss of terrestrial ecosystems to safeguard nature for biodiversity and humanity
Simmonds, J. S.; Suarez-Castro, A. F.; Reside, A. E.; Watson, J. E. M.; Allan, J. R.; Borrelli, P.; Dudley, N.; Edwards, S.; Fuller, R. A.; Game, E. T.; Linke, S.; Maxwell, S. L.; Panagos, P.; Puydarrieux, P.; Quetier, F.; Runting, R. K.; Santini, T.; Sonter, L. J.; Maron, M.
10.1101/2021.02.07.428694 — ecology — Posted on 2021-02-08
3125 A human antibody with blocking activity to RBD proteins of multiple SARS-CoV-2 variants including B.1.351 showed potent prophylactic and therapeutic efficacy against SARS-CoV-2 in rhesus macaques
Gu, C.; cao, X.; Wang, Z.; Hu, X.; Yao, Y.; Zhou, Y.; Liu, P.; Liu, X.; Gao, G.; Hu, X.; Liang, H.; Chen, Z.; Gao, L.; Peng, Y.; Jia, F.; Shan, C.; Yu, L.; Liu, K.; Li, N.; Guo, W.; Jiang, G.; Min, J.; Zhang, J.; Yang, L.; Shi, M.; Hou, T.; Li, Y.; Liang, W.; Lu, G.; Yang, C.; Wang, Y.; Xia, K.; Xiao, Z.; Xue, J.; Huang, X.; Chen, X.; Ma, H.; Song, D.; Pan, Z.; Wang, X.; Guo, H.; Liang, H.; Yuan, Z.; Guan, W.; Deng, S.-J.
10.1101/2021.02.07.429299 — microbiology — Posted on 2021-02-08
3126 Consistent population activity on the scale of minutes in the mouse hippocampus
Liu, Y.; Levy, S. J.; Mau, W.; Geva, N.; Rubin, A.; Ziv, Y.; Hasselmo, M.; Howard, M.
10.1101/2021.02.07.430172 — neuroscience — Posted on 2021-02-08
3127 Insulin-Like Growth Factor I Couples Metabolism With Circadian Activity Through Hypothalamic Orexin Neurons
Pignatelli, J.; Fernandez de Sevilla, M. E.; Sperber, J.; Horrillo, D.; Medina-Gomez, G.; Torres Aleman, I.
10.1101/2021.02.07.429949 — neuroscience — Posted on 2021-02-08
3128 A DNA-origami NanoTrap for studying the diffusion barriers formed by Phe-Gly-rich nucleoporins
Shen, Q.; Tian, T.; Xiong, Q.; Fisher, P. D. E.; Xiong, Y.; Melia, T.; Lusk, C. P.; Lin, C.
10.1101/2021.02.07.430177 — synthetic biology — Posted on 2021-02-08
3131 Genome-wide Detection of Cytosine Methylations in Plant from Nanopore sequencing data using Deep Learning
Ni, P.; Huang, N.; Nie, F.; Zhang, J.; Zhang, Z.; Wu, B.; Liu, W.; Bai, L.; Xiao, C.-L.; Luo, F.; Wang, J.
10.1101/2021.02.07.430077 — bioinformatics — Posted on 2021-02-08
3133 Behavioural adaptations in egg laying ancestors facilitate evolutionary transitions to live birth
Pettersen, A. K.; Feiner, N.; Noble, D. W. A.; While, G. M.; Cornwallis, C. K.; Uller, T.
10.1101/2021.02.07.430163 — evolutionary biology — Posted on 2021-02-08
3134 Heterogeneous strains in tissue collagen show that high strains locally suppress degradation by collagenase
Saini, K.; Tiwari, M.; Cho, S.; Jalil, A.; Vashisth, M.; Irianto, J.; Andrechak, J.; Dooling, L.; Alvey, C.; Kasznel, A.; Chenoweth, D. M.; Yamamoto, K.; Discher, D.
10.1101/2021.02.07.430141 — molecular biology — Posted on 2021-02-08
3139 Age-related deficits in rapid visuomotor decision-making
Gomez-Granados, A.; Barany, D.; Schrayer, M.; Kurtzer, I.; Bonnet, C. T.; Singh, T.
10.1101/2021.02.07.430152 — neuroscience — Posted on 2021-02-08
3141 Two distinct types of nodes of Ranvier support auditory nerve function in the mouse cochlea
Panganiban, C.; Barth, J. L.; Tan, J.; Kenyaria, N. V.; McClaskey, C. M.; Dias, J. W.; Harris, K. C.; Lang, H.
10.1101/2021.02.07.430087 — neuroscience — Posted on 2021-02-08
3146 Genome wide mapping of DNA lesions by Repair Assisted Damage Detection sequencing - RADD-Seq
Gilat, N.; Fridman, D.; Sharim, H.; Margalit, S.; Gassman, N.; Michaeli, Y.; Ebenstein, Y.
10.1101/2021.02.07.430183 — genomics — Posted on 2021-02-08
3149 Leaf economics explained by optimality principles
Wang, H.; Prentice, I. C.; Wright, I. J.; Qiao, S.; Xu, X.; Kikuzawa, K.; Stenseth, N. C.
10.1101/2021.02.07.430028 — ecology — Posted on 2021-02-08
3150 Selection and structural characterisation of anti-TREM2 scFvs that reduce levels of shed ectodomain
Szykowska, A.; Chen, Y.; Smith, T. B.; Preger, C.; Yang, J.; Qian, D.; Mukhopadhyay, S.; Wigren, E.; Neame, S. J.; Gräslund, S.; Persson, H.; Atkinson, P. J.; Di Daniel, E.; Mead, E.; Wang, J.; Davis, J. B.; Burgess-Brown, N. A.; Bullock, A. N.
10.1101/2021.02.07.430123 — molecular biology — Posted on 2021-02-08
3151 Nucleosomal Asymmetry Shapes Histone Mark Binding and Promotes Poising at Bivalent Domains
Bryan, E.; Warburton, M.; Webb, K. M.; McLaughlin, K. A.; Spanos, C.; Ambrosi, C.; Major, V.; Baubec, T.; Rappsilber, J.; Voigt, P.
10.1101/2021.02.08.430127 — molecular biology — Posted on 2021-02-08
3152 c-MAF dependent perivascular macrophages regulate diet induced metabolic syndrome
Moura Silva, H.; Kitoko, J. Z.; Queiroz, C. P.; Kroehling, L.; Matheis, F.; Lu Yang, K.; Ren-Fielding, C.; Littman, D.; Bozza, M.; Mucida, D.; Lafaille, J.
10.1101/2021.02.07.430147 — immunology — Posted on 2021-02-08
3153 Impact of Propionic Acidemia on Brain Astrocytes
Cotrina, M. L.; Sun, W.; Chen, M. J.; Guenzel, A. J.; Zhagnay, J.; Goldman, J.; Barry, M.; Nedergaard, M.
10.1101/2021.02.07.428966 — neuroscience — Posted on 2021-02-08
3154 Chronic paternal morphine exposure increases sensitivity to morphine-derived antinociception
Toussaint, A. B.; Foster, W.; Jones, J. M.; Kaufmann, S.; Wachira, M.; Hughes, R.; Bongiovanni, A. R.; Famularo, S. T.; Dunham, B. P.; Schwark, R.; Fried, N. T.; Wimmer, M.; Abdus-Saboor, I.
10.1101/2021.02.07.430143 — neuroscience — Posted on 2021-02-08
3155 Genomic analyses of 10,376 individuals provides comprehensive map of genetic variations, structure and reference haplotypes for Chinese population
Cong, P.; Bai, W.; Li, J.; Li, N.; Gai, S.; Khederzadeh, S.; Liu, Y.; Qiu, M.; Zhu, X.; Zhao, P.; Xia, J.; Yu, S.; Zhao, W.; Liu, J.; Guan, P.; Qian, Y.; Tao, J.; Yang, M.; Tian, G.; Xie, S.; Liu, K.; Tang, B.; Zheng, H.
10.1101/2021.02.06.430086 — genetics — Posted on 2021-02-08
3156 Human RNA Nm-MTase FTSJ1: new tRNA targets and role in the regulation of brain-specific genes.
DIMITROVA, D. G.; BRAZANE, M.; TAO, Y.; MARCHAND, V.; SCHAEFER, E.; STARK, Z.; DELATYCKI, M.; DUDDING, T.; GECZ, J.; TEYSSET, L.; PITON, A.; MOTORIN, Y.; CARRE, C.
10.1101/2021.02.06.430044 — genetics — Posted on 2021-02-08
3157 Strain dynamics of specific contaminant bacteria modulate the performance of ethanol biorefineries
Lino, F. S. d. O.; Misiakou, M.-A.; Kang, K.; Li, S.; da Costa, B. L. V.; Basso, T. O.; Panagiotou, G.; Sommer, M. O. A.
10.1101/2021.02.07.430133 — microbiology — Posted on 2021-02-08
3158 The landscape of high-affinity human antibodies against intratumoral antigens
Rakocevic, G.; Gotlova, I.; de Santiago, I.; Toptas, B. C.; Popovic, M.; Popovic, M.; Leone, D. A.; Stachyra, A. L.; Kural, D.; Biasci, D.
10.1101/2021.02.06.430058 — immunology — Posted on 2021-02-08
3159 Spatial transcriptomics reveals unique molecular fingerprints of human nociceptors
Tavares-Ferreira, D.; Shiers, S.; Ray, P.; Wangzhou, A.; Jeevakumar, V.; Sankaranarayanan, I.; Chamessian, A.; Copits, B.; Dougherty, P. M.; Gereau, R.; Burton, M. D.; Dussor, G.; Price, T. J.
10.1101/2021.02.06.430065 — neuroscience — Posted on 2021-02-08
3166 Spray-induced gene silencing as a potential tool to control potato late blight disease
Kalyandurg, P. B.; Sundararajan, P.; Dubey, M.; Ghadamgahi, F.; Zahid, M. A.; Whisson, S. C.; Vetukuri, R. R.
10.1101/2021.02.07.430140 — plant biology — Posted on 2021-02-08
3167 Biophysical and proteomic analyses suggest functions of Pseudomonas syringae pv tomato DC3000 extracellular vesicles in bacterial growth during plant infection
Janda, M.; Ludwig, C.; Rybak, K.; Meng, C.; Stigliano, E.; Botzenhardt, L.; Szulc, B.; Sklenar, J.; Menke, F. L. H.; Malone, J. G.; Brachmann, A.; Klingl, A.; Robatzek, S.
10.1101/2021.02.08.430144 — plant biology — Posted on 2021-02-08
3171 A water-reward task assay for evaluating mouse mutualistic cooperative behavior
Feng, W.; Zhang, Y.; Wang, Z.; Wang, T.; Pang, Y.; Zou, Y.; Huang, H.; Sheng, C.; Xiao, M.
10.1101/2021.02.06.430037 — animal behavior and cognition — Posted on 2021-02-08
3182 Innovations to expand drone data collection and analysis for rangeland monitoring
Gillan, J.; Ponce-Campos, G. E.; Swetnam, T. L.; Gorlier, A.; Heilman, P.; McClaran, M. P.
10.1101/2021.02.05.430004 — ecology — Posted on 2021-02-08
3184 Lesion site and therapy time predict responses to a therapy for anomia after stroke: a prognostic model development study
Hope, T. M. H.; Nardo, D.; Holland, R.; Ondobaka, S.; Akkad, H.; Price, C. J.; Leff, A.; Crinion, J.
10.1101/2021.02.05.429894 — neuroscience — Posted on 2021-02-08
3195 A Network Propagation Approach to Prioritize Long Tail Genes in Cancer
Mohsen, H.; Gunasekharan, V.; Qing, T.; Negahban, S.; Szallasi, Z.; Pusztai, L.; Gerstein, M.
10.1101/2021.02.05.429983 — bioinformatics — Posted on 2021-02-08
3198 An Incrementally Updatable and Scalable System for Large-Scale Sequence Search using LSM Trees
Almodaresi, F.; Khan, J.; Madaminov, S.; Pandey, P.; Ferdman, M.; Johnson, R.; Patro, R.
10.1101/2021.02.05.429839 — bioinformatics — Posted on 2021-02-08
3199 Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor
Xu, H. E.; Zhuang, Y.; Krumm, B.; Zhang, H.; Zhou, X. E.; Wang, Y.; Huang, X.-P.; Liu, Y.; Cheng, X.; Jiang, Y.; Jiang, H.; Zhang, C.; Yi, W.; Roth, B. L.; Zhang, Y.
10.1101/2021.02.07.430101 — molecular biology — Posted on 2021-02-08
3200 Modulating the left inferior frontal cortex by task domain, cognitive challenge and tDCS
Nardo, D.; Pappa, K.; Duncan, J.; Zeidman, P.; Callaghan, M.; Leff, A.; Crinion, J.
10.1101/2021.02.05.429968 — neuroscience — Posted on 2021-02-08
3201 Bacterium-Enabled Transient Gene Activation by Artificial Transcription Factor for Resolving Gene Regulation in Maize
Zhao, M.; Peng, Z.; Qin, Y.; Zhang, L.; Tian, B.; Chen, Y.; Liu, Y.; Lin, G.; Zheng, H.; He, C.; Lv, K.; Trick, H. N.; Liu, Y.; Cho, M.-J.; Park, S.; Wei, H.; Zheng, J.; White, F. F.; Liu, S.
10.1101/2021.02.05.429970 — plant biology — Posted on 2021-02-08
3208 Ethanol-guided behavior in Drosophila larvae
Schumann, I.; Berger, M.; Nowag, N.; Schaefer, Y.; Saumweber, J.; Scholz, H.; Thum, A. S.
10.1101/2021.02.07.430116 — animal behavior and cognition — Posted on 2021-02-08
3211 Bidirectional neuronal migration coordinates retinal morphogenesis bypreventing spatial competition
Rocha-Martins, M.; Kretzschmar, J.; Nerli, E.; Weigert, M.; Icha, J.; Myers, E. W.; Norden, C.
10.1101/2021.02.08.430189 — developmental biology — Posted on 2021-02-08
3212 Impact of cobas PCR Media Freezing on SARS-CoV-2 Viral RNA Integrity and Whole Genome Sequencing Analyses
Benoit, P.; Point, F.; Gagnon, S.; Kaufmann, D. E.; Tremblay, C.; Harrigan, P. R.; Hardy, I.; Coutlee, F.; Grandjean Lapierre, S.
10.1101/2021.02.05.430022 — molecular biology — Posted on 2021-02-08
3214 Loss of ClpP Function in Clostridioides difficile 630 Significantly Impacts Sporulation Systems
Bishop, C. E.; Shadid, T.; Lavey, N. P.; Kempher, M. L.; Ahsan, N.; Ballard, J. D.; Duerfeldt, A. S.
10.1101/2021.02.05.429978 — microbiology — Posted on 2021-02-08
3215 Recombinant chimpanzee adenovirus AdC7 expressing dimeric tandem-repeat RBD of SARS-CoV-2 spike protein protects mice against COVID-19
Xu, K.; An, Y.; Li, Q.; Huang, W.; Han, Y.; Zheng, T.; Fang, F.; Liu, H.; Liu, C.; Gao, P.; Xu, S.; Liu, W. J.; Bi, Y.; Wang, Y.; Zhou, D.; Wang, Q.; Hou, W.; Xia, Q.; Gao, G. F.; Dai, L.
10.1101/2021.02.05.429860 — immunology — Posted on 2021-02-08
3217 Leaky wiring of the brain: local cluster of coupled synapses and extracellular signal integration
Dietrich, D.; Matthews, E.; Sun, W.; McMahon, S.; Döngi, M.; Halka, L.; Anders, S.; Müller, J. A.; Steinlein, P.; Vana, N.; van Dyk, G.; Pitsch, J.; Becker, A. J.; Pfeifer, A.; Kavalali, E. T.; Lamprecht, A.; Henneberger, C.; Stein, V.; Schoch, S.
10.1101/2021.02.05.429974 — neuroscience — Posted on 2021-02-08
3220 Tick infestation probability increases with human recreation and exploratory behaviour in great tits
Rollins, R. E.; Mouchet, A.; Margos, G.; Fingerle, V.; Becker, N. S.; Dingemanse, N. J.
10.1101/2020.03.06.978973 — ecology — Posted on 2021-02-08
3221 Cholesterol recognition motifs in the transmembrane domain of the tyrosine kinase receptor family: the case for TRKB
Cannarozzo, C.; Fred, S. M.; Girych, M.; Biojone, C.; Enkavi, G.; Rog, T.; Vattulainen, I.; Casarotto, P. C.; Castren, E.
10.1101/734012 — neuroscience — Posted on 2021-02-08
3222 Brain expressed FKBP5 delineates a therapeutic subtype of severe mental illness
Matosin, N.; Arloth, J.; Martinelli, S.; Czamara, D.; Maitra, M.; Halldorsdottir, T.; Cruceanu, C.; Kaul, D.; Gassen, N.; Hafner, K.; Mueller, N.; Worf, K.; Rehawi, G.; Nagy, C.; Scarr, E.; Tao, R.; Jaffe, A. E.; Arzberger, T.; Falkai, P.; Kleinmann, J.; Weinberger, D.; Mechawar, N.; Schmitt, A.; Dean, B.; Turecki, G.; Hyde, T. M.; Binder, E.
10.1101/2021.01.27.428487 — neuroscience — Posted on 2021-02-08
3223 Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation
Brunner, A.-D.; Thielert, M.; Vasilopoulou, C.; Ammar, C.; Coscia, F.; Mund, A.; Horning, O. B.; Bache, N.; Apalategui, A.; Lubeck, M.; Raether, O.; Park, M.; Richter, S.; Fischer, D. S.; Meier, F.; Theis, F. J.; Mann, M.
10.1101/2020.12.22.423933 — systems biology — Posted on 2021-02-08
3227 High coverage whole genome sequencing of the expanded 1000 Genomes Project cohort including 602 trios
Byrska-Bishop, M.; Evani, U. S.; Zhao, X.; Basile, A. O.; Abel, H. J.; Regier, A. A.; Corvelo, A.; Clarke, W. E.; Musunuri, R.; Nagulapalli, K.; Fairley, S.; Runnels, A.; Winterkorn, L.; Lowy-Gallego, E.; The Human Genome Structural Variation Consortium, ; Flicek, P.; Germer, S.; Brand, H.; Hall, I. M.; Talkowski, M. E.; Narzisi, G.; Zody, M. C.
10.1101/2021.02.06.430068 — genomics — Posted on 2021-02-07
3229 Optical regulation of endogenous RhoA reveals switching of cellular responses by signal amplitude
Ju, J.; Ning, L.; Lee, H. N.; Chun, H.; Zhou, X. X.; Ryu, H.; Lee, Y. W.; Lee-Richerson, A. I.; Jeong, C.; Lin, M.; Seong, J.
10.1101/2021.02.05.430013 — bioengineering — Posted on 2021-02-07
3230 Multi-omic characterization of the thermal stress phenome in the stony coral Montipora capitata
Pathmanathan, J.; Williams, A.; Stephens, T. G.; Su, X.; Chiles, E. N.; Conetta, D.; Putnam, H. M.; Bhattacharya, D.
10.1101/2021.02.05.429981 — genomics — Posted on 2021-02-07
3231 Self-assembling SARS-CoV-2 nanoparticle vaccines targeting the S protein induces protective immunity in mice
Liu, X.; Song, H.; Jiang, J.; Gao, X.; Yi, Y.; Shang, Y.; Li, J.; Li, D.; Zeng, Z.; Li, Y.; Zhang, Z.
10.1101/2021.02.05.428685 — immunology — Posted on 2021-02-07
3232 Somatostatin-positive Interneurons Contribute to Seizures in SCN8A Epileptic Encephalopathy
Wengert, E. R.; Wedgwood, K. C.; Wagley, P. K.; Strohm, S. M.; Panchal, P. S.; Idrissi, A. M.; Wenker, I. C.; Gaykema, R. P.; Patel, M. K.
10.1101/2021.02.05.429987 — neuroscience — Posted on 2021-02-07
3234 Information Content Differentiates Enhancers From Silencers in Mouse Photoreceptors
Friedman, R. Z.; Granas, D. M.; Myers, C. A.; Corbo, J. C.; Cohen, B. A.; White, M. A.
10.1101/2021.02.05.429997 — systems biology — Posted on 2021-02-07
3235 Whole Animal Multiplexed Single-Cell RNA-Seq Reveals Plasticity of Clytia Medusa Cell Types
Chari, T.; Weissbourd, B.; Gehring, J.; Ferraioli, A.; Leclere, L.; Herl, M.; Gao, F.; Chevalier, S.; Copley, R. R.; Houliston, E.; Anderson, D. J.; Pachter, L.
10.1101/2021.01.22.427844 — systems biology — Posted on 2021-02-07
3239 The role of IL-1 in adipose browning and muscle wasting in CKD-associated cachexia
Cheung, W. W.; Zheng, R.; Hao, S.; Wang, Z.; Gonzalez, A.; Zhou, P.; Hoffman, H. M.; Mak, R. H.
10.1101/2021.02.05.429984 — physiology — Posted on 2021-02-07
3240 Elephant seal muscle cells adapt to sustained glucocorticoid exposure by shifting their metabolic phenotype
Torres-Velarde, J. M.; Kolora, S. R. R.; Khudyakov, J. I.; Crocker, D. E.; Sudmant, P. H.; Vazquez-Medina, J. P.
10.1101/2021.02.05.429992 — physiology — Posted on 2021-02-07
3241 The hepatocyte insulin receptor is required to program rhythmic gene expression and the liver clock
Fougeray, T.; Polizzi, A.; Regnier, M.; Fougerat, A.; Ellero-Simatos, S.; Lippi, Y.; Smati, S.; Lasserre, F.; Tramunt, B.; Huillet, M.; Dopavogui, L.; Smith, L.; Naylies, C.; Sommer, C.; Benani, A.; Haas, J. T.; Wahli, W.; Duez, H.; Gourdy, P.; Gamet-Payrastre, L.; Burnol, A.-F.; Loiseau, N.; Postic, C.; Montagner, A.; Guillou, H.
10.1101/2021.02.05.430014 — physiology — Posted on 2021-02-07
3242 Cardiac and behavioural responses to hypoxia and warming in free-swimming gilthead seabream Sparus aurata
Mignucci, A.; Bourjea, J.; Forget, F.; Allal, H.; Dutto, G.; Gasset, E.; McKenzie, D. J.
10.1101/2021.02.05.429945 — physiology — Posted on 2021-02-07
3243 Redefining tumor classification and clinical stratification through a colorectal cancer single-cell atlas
Khaliq, A. M.; kurt, z.; Grunvald, M. W.; Erdogan, C.; Turgut, S. S.; Rand, T.; Khare, S.; Borgia, J. A.; Hayden, D. M.; Pappas, S. G.; Govekar, H. R.; Bhama, A. R.; Singh, A.; Jacobson, R. A.; Kam, A. E.; Zloza, A.; Reiser, J.; Catenacci, D. V.; Turaga, K.; Radovich, M.; Thyparambil, S.; Levy, M. A.; Subramanian, J.; Kuzel, T. M.; Sadanandam, A.; Hussain, A.; El-Rayes, B.; Salahudeen, A.; Masood, A.
10.1101/2021.02.02.429256 — cancer biology — Posted on 2021-02-07
3247 DLX5/6 GABAergic expression affects social vocalization: implications for human evolution
Levi, G.; de Lombares, C.; Giuliani, C.; Iannuzzi, V.; Aouci, R.; Garagnani, P.; Franceschi, C.; Grimaud-Herve, D.; Narboux-Neme, N.
10.1101/2020.07.24.218065 — evolutionary biology — Posted on 2021-02-07
3248 Predicted distribution of a rare and understudied forest carnivore: Humboldt martens (Martes caurina humboldtensis)
Moriarty, K. M.; Thompson, J.; Delheimer, M. S.; Barry, B. R.; Linnell, M. A.; Levi, T.; Hamm, K.; Early, D.; Gamblin, H.; Szykman Gunther, M.; Ellison, J. L.; Prevey, J.; Hartman, J.; Davis, R.
10.1101/2021.02.05.429381 — ecology — Posted on 2021-02-07
3252 Molecular and cellular insight into Escherichia coli SslE and its role during biofilm maturation
Corsini, P.; Wang, S.; Rehman, S.; Fenn, K.; Sagar, A.; Sirovica, S.; Cleaver, L.; Dorgan, B.; Sewell, L. M.; Lynham, S.; Jarvis, J.; Carpenter, G.; Curtis, M. A.; Bernado, P.; Darbari, V. C.; Garnett, J. A.
10.1101/2021.02.07.430137 — microbiology — Posted on 2021-02-07
3254 Functional ultrasound imaging of the spreading activity following optogenetic stimulation of the rat visual cortex
Provansal, M.; Labernede, G.; Joffrois, C.; Rizkallah, A.; Goulet, R.; Valet, M.; Deschamps, W.; Ferrari, U.; Chaffiol, A.; Dalkara, D.; Sahel, J.-A.; Tanter, M.; Picaud, S.; Gauvain, G.; Arcizet, F.
10.1101/2021.02.05.429985 — neuroscience — Posted on 2021-02-07
3256 C-bouton components on rat extensor digitorum longus motoneurons are resistant to chronic functional overload
Kissane, R. W.; Ghaffari-Rafi, A.; Tickle, P. G.; Chakrabarty, S.; Egginton, S.; Brownstone, R. M.; Smith, C. C.
10.1101/2021.02.05.429939 — neuroscience — Posted on 2021-02-07
3257 Targeting interleukin-1 for reversing fat browning and muscle wasting in infantile nephropathic cystinosis
Cheung, W. W.; Hao, S.; Zheng, R.; Wang, Z.; Gonzalez, A.; Zhou, P.; Hoffman, H. M.; Mak, R. H.
10.1101/2021.02.05.429989 — physiology — Posted on 2021-02-07
3267 Exercise Attenuates Sickness Behavior And Protects Against Dopaminergic Impairment Induced By Neuroinflammation
Alves, A. C. d. B.; Staats, A.; Speck, A. E.; Lopes, S. C.; Scheffer, D. d. L.; Melo, H. M.; Prediger, R. D.; Martins, R. d. P.; Latini, A.; Aguiar, A. S.
10.1101/2021.02.05.429925 — animal behavior and cognition — Posted on 2021-02-07
3270 Targeting CTP Synthetase 1 to Restore Interferon Induction and Impede Nucleotide Synthesis in SARS-CoV-2 Infection
Rao, Y.; Wang, T.-Y.; Qin, C.; Espinosa, B.; Liu, Q.; Ekanayake, A.; Zhao, J.; Savas, A. C.; Zhang, S.; Zarinfar, M.; Liu, Y.; Zhu, W.; Graham, N. A.; Jiang, T.; Zhang, C.; Feng, P.
10.1101/2021.02.05.429959 — microbiology — Posted on 2021-02-07
3271 Human immunoglobulin from transchromosomic bovines hyperimmunized with SARS-CoV-2 spike antigen efficiently neutralizes viral variants.
Liu, Z.; Wu, H.; Egland, K. A.; Gilliland, T. C.; Dunn, M. D.; Luke, T. C.; Sullivan, E. J.; Klimstra, W. B.; Bausch, C. L.; Whelan, S. P. J.
10.1101/2021.02.06.430072 — microbiology — Posted on 2021-02-07
3272 Long non-coding RNAs bind to proteins relevant to the ethanol tolerance in yeast: a systems biology view
Marques, L. F.; Wolf, I. R.; Lazari, L. C.; Almeida, L. F. d.; Schnepper, A. P.; Cardoso, L. H.; Moraes, L. N. d.; Grotto, R. M. T.; Simoes, R. P.; Ramos, E.; Valente, G. T.
10.1101/2021.02.07.430053 — microbiology — Posted on 2021-02-07
3273 A human antibody with blocking activity to RBD proteins of multiple SARS-CoV-2 variants including B.1.351 showed potent prophylactic and therapeutic efficacy against SARS-CoV-2 in rhesus macaques
Deng, S.-J.; cao, X.; Gu, C.; Wang, Z.; Liu, P.; Liu, X.; Gao, L.; Jia, F.; Yu, L.; Li, N.; Jiang, G.; Zhang, J.; Yang, L.; Shi, M.; Hou, T.; Li, Y.; Liang, W.; Lu, G.; Yang, C.; Wang, Y.; Xia, K.; Xiao, Z.; Xue, J.; Huang, X.; Chen, X.; Pan, Z.; Wang, X.; Guo, H.; Liang, H.; Yao, Y.; Gao, G.; Peng, Y.; Hu, X.; Min, J.; Zhou, Y.; Liu, K.; Guo, W.; Yuan, Z.; Song, D.; Guan, W.; Ma, H.; Hu, X.; Zhang, Y.; Chen, Z.; Shan, C.
10.1101/2021.02.07.429299 — microbiology — Posted on 2021-02-07
3275 Adaptive maternal effects in early life history traits help to maintain ecological resilience in novel environments for two contrasting Senecio species
Walter, G. M.; du Plessis, S.; Terranova, D.; la Spina, E.; Majorana, M. G.; Pepe, G.; Clark, J.; Cozzolino, S.; Cristaudo, A. E.; Hiscock, S. J.; Bridle, J. R.
10.1101/2021.02.04.429835 — evolutionary biology — Posted on 2021-02-07
3278 Single-cell characterization of step-wise acquisition of carboplatin resistance in ovarian cancer
Wenzel, A. T.; Champa, D.; Venkatesh, H.; Sun, S.; Tsai, C.-Y.; Mesirov, J. P.; Bui, J. D.; Howell, S. B.; Harismendy, O.
10.1101/231548 — cancer biology — Posted on 2021-02-07
3282 Predictive systems biomarkers of response to immune checkpoint inhibitors
Lapuente-Santana, O.; van Genderen, M.; Hilbers, P.; Finotello, F.; Eduati, F.
10.1101/2021.02.05.429977 — cancer biology — Posted on 2021-02-07
3283 Integrative genome-wide analysis reveals EIF3A as a key downstream regulator of translational repressor protein Musashi 2 (MSI2)
Karmakar, S.; Ramirez, O.; Paul, K. V.; Gupta, A. K.; Botti, V.; Mozos, I. R. d. l.; Neuenkirchen, N.; Ross, R. J.; Neugebauer, K. M.; Pillai, M. M.
10.1101/2021.02.06.428911 — cancer biology — Posted on 2021-02-07
3289 Ex vivo delivery of regulatory T cells for control of alloimmune priming in the donor lung
Miyamoto, E.; Takahagi, A.; Ohsumi, A.; Martinu, T.; Hwang, D.; Boonstra, K.; Joe, B.; Juan Umana, M.; Bei, K.; Vosoughi, D.; Liu, M.; Cypel, M.; Keshavjee, S.; Juvet, S. C.
10.1101/2021.02.07.430098 — immunology — Posted on 2021-02-07
3290 TNF signalling fine-tunes Langerhans cell transcriptional programmes mediating adaptive immunity.
Davies, J.; Vallejo, A. F.; Sirvent, S.; Porter, G.; Clayton, K.; Qumbelo, Y.; Stumpf, P.; West, J.; Gray, C. M.; Chigorimbo-Murefu, N. T. L.; MacArthur, B.; Polak, M. E.
10.1101/2021.02.07.430111 — systems biology — Posted on 2021-02-07
3291 Long-term persistence of crAss-like phage crAss001 is associated with phase variation in Bacteroides intestinalis
Shkoporov, A. N.; Khokhlova, E. V.; Stephens, N.; Hueston, C.; Seymour, S.; Hryckowian, A. J.; Scholz, D.; Ross, R. P.; Hill, C.
10.1101/2020.12.02.408625 — microbiology — Posted on 2021-02-07
3292 Temporal dynamics of animacy categorization in the brain of patients with mild cognitive impairment
Karimi, H.; Marefat, H.; Khanbagi, M.; Kalafatis, C.; Modarres, M. H.; Vahabi, Z.; Khaligh-Razavi, S.-M.
10.1101/2020.11.20.390435 — neuroscience — Posted on 2021-02-07
3294 Expansion of cortical layers 2 and 3 in human left temporal cortex associates with verbal intelligence
Heyer, D. B.; Wilbers, R.; Galakhova, A. A.; Hartsema, E.; Braak, S.; Hunt, S.; Verhoog, M. B.; Muijtjens, M. L.; Mertens, E. J.; Idema, S.; Baayen, J. C.; de Witt Hamer, P. C.; Klein, M.; McGraw, M.; Lein, E. S.; de Kock, C. P. J.; Mansvelder, H. D.; Goriounova, N. A.
10.1101/2021.02.07.430103 — neuroscience — Posted on 2021-02-07
3296 Huntingtin CAG expansion impairs germ layer patterning in synthetic human gastruloids through polarity defects.
Galgoczi, S.; Ruzo, A.; Markopoulos, C.; Yoney, A.; Phan-Everson, T.; Haremaki, T.; Metzger, J. J.; Etoc, F.; Brivanlou, A. H.
10.1101/2021.02.06.430005 — developmental biology — Posted on 2021-02-07
3297 Piezo2 mediates ultrasonic hearing via cochlear outer hair cells in mice
Li, J.; Liu, S.; Song, C.; Hu, Q.; Zhao, Z.; Deng, T.; Zou, L.; Wang, S.; Chen, J.; Liu, L.; Hou, H.; Yuan, K.; Zheng, H.; Liu, Z.; Chen, X.; Sun, W.; Xiao, B.; Xiong, W.
10.1101/2020.10.09.332643 — neuroscience — Posted on 2021-02-07
3298 Redefining tumor classification and clinical stratification through a colorectal cancer single-cell atlas
Khaliq, A. M.; kurt, z.; Grunvald, M. W.; Erdogan, C.; Turgut, S. S.; Rand, T.; Khare, S.; Borgia, J. A.; Hayden, D. M.; Pappas, S. G.; Govekar, H. R.; Bhama, A. R.; Singh, A.; Jacobson, R. A.; Kam, A. E.; Zloza, A.; Reiser, J.; Catenacci, D. V.; Turaga, K.; Radovich, M.; Thyparambil, S.; Levy, M. A.; Subramanian, J.; Kuzel, T. M.; Sadanandam, A.; Hussain, A.; El-Rayes, B.; Salahudeen, A.; Masood, A.
10.1101/2021.02.02.429256 — cancer biology — Posted on 2021-02-07
3299 Diverse molecular mechanisms contribute to differential expression of human duplicated genes
Shew, C. J.; Carmona-Mora, P.; Soto, D. C.; Mastoras, M.; Roberts, E.; Rosas, J.; Jagannathan, D.; Kaya, G.; O'Geen, H.; Dennis, M. Y.
10.1101/2020.11.27.401752 — genomics — Posted on 2021-02-07
3305 Temporo-cerebellar connectivity underlies timing constraints in audition
Stockert, A.; Schwartze, M.; Poeppel, D.; Anwander, A.; Kotz, S. A.
10.1101/2021.02.06.430038 — neuroscience — Posted on 2021-02-07
3307 Bayesian Decoder Models with a Discriminative Observation Process
Rezaei, M. R.; Hadjinicolaou, A. E.; Cash, S. S.; Eden, U.; Yousefi, A.
10.1101/2020.07.11.198564 — bioinformatics — Posted on 2021-02-06
3308 Depth Dataset Using Microsoft Kinect-v2
Heravi, H.; Delgarmi, M.; Rahimpour Jounghani, A.; shahrezaie, A.; Ebrahimi, A.; Shamsi, M.
10.1101/2021.02.04.429850 — bioengineering — Posted on 2021-02-06
3312 Sex pheromone signal and stability covary with fitness
Blankers, T.; Lievers, R.; Plata, C.; van Wijk, M.; van Veldhuizen, D.; Groot, A. T.
10.1101/2021.02.05.429875 — evolutionary biology — Posted on 2021-02-06
3313 Landscape composition mediates suppression of major pests by natural enemies in conventional cruciferous vegetables
Zhang, J.; You, S.; Niu, D.; Gavilanes Guaman, K. G.; Wang, A.; Saqib, H. S. A.; He, W.; Yu, Y.; Yang, G.; Pozsgai, G.; You, M.
10.1101/2021.02.04.429816 — ecology — Posted on 2021-02-06
3315 celldeath: a tool for detection of cell death in transmitted light microscopy images by deep learning-based visual recognition
La Greca, A.; Perez, N.; Milone, P. M.; Castaneda, S.; Scarafia, M. A.; Möbbs, A. M.; Waisman, A.; Moro, L. N.; Sevlever, G.; Luzzani, C.; Miriuka, S. G.
10.1101/2020.03.22.002253 — cell biology — Posted on 2021-02-06
3317 Cold adapted desiccation-tolerant bacteria isolated from polar soils presenting high resistance to anhydrobiosis
Nobrega, F.; Duarte, R. T. D.; Torres-Ballesteros, A. M.; Queiroz, L. L.; Whyte, L. G.; Pellizari, V. H.
10.1101/2021.02.06.430066 — microbiology — Posted on 2021-02-06
3321 Mechanically Transduced Immunosorbent Assay To Measure Protein-Protein Interactions
Petell, C. J.; Randene, K.; Pappas, M.; Sandoval, D.; Strahl, B.; Harrison, J. S.; Steimel, J. P.
10.1101/2021.02.05.429999 — biochemistry — Posted on 2021-02-06
3322 NeuroSCORE: A Genome-wide Omics-Based Model to Identify Candidate Disease Genes of the Central Nervous System
Davis, K. W.; Bilancia, C. G.; Martin, M.; Vanzo, R.; Rimmasch, M.; Hom, Y.; Uddin, M.; Serrano, M.
10.1101/2021.02.04.429640 — genomics — Posted on 2021-02-06
3323 Consistent ultra-long DNA sequencing with automated slow pipetting
Prall, T. M.; Neumann, E. K.; Karl, J. A.; Shortreed, C. G.; Baker, D. A.; Bussan, H. E.; Wiseman, R. W.; O'Connor, D. H.
10.1101/2020.09.18.302471 — genomics — Posted on 2021-02-06
3324 Cancer relevance of human genes
Qing, T.; Mohsen, H.; Cannataro, V. L.; Marczyk, M.; Rozenblit, M.; Foldi, J.; Murray, M. F.; Townsend, J. P.; Kluger, Y.; Gerstein, M.; Pusztai, L.
10.1101/2021.02.04.429823 — genomics — Posted on 2021-02-06
3326 Interpreting machine learning models to investigate circadian regulation and facilitate exploration of clock function
Gardiner, L.-J.; Rusholme-Pilcher, R.; Colmer, J.; Rees, H.; Crescente, J. M.; Carrieri, A. P.; Duncan, S.; Pyzer-Knapp, E. O.; Krishna, R.; Halll, A.
10.1101/2021.02.04.429826 — genomics — Posted on 2021-02-06
3327 TRNP1 sequence, function and regulation co-evolve with cortical folding in mammals
Kliesmete, Z.; Wange, L. E.; Vieth, B.; Esgleas, M.; Radmer, J.; Huelsmann, M.; Geuder, J.; Richter, D.; Ohnuki, M.; Goetz, M.; Hellmann, I.; Enard, W.
10.1101/2021.02.05.429919 — evolutionary biology — Posted on 2021-02-06
3328 Capacity of countries to reduce biological invasions
Latombe, G.; Seebens, H.; Lenzner, B.; Courchamp, F.; Dullinger, S.; Golivets, M.; Kühn, I.; Leung, B.; Roura-Pascual, N.; Cebrian, E.; Dawson, W.; Diagne, C.; Jeschke, J. M.; Perez-Granados, C.; Liu, C.; Moser, D.; Turbelin, A.; Visconti, P.; Essl, F.
10.1101/2021.02.04.429788 — ecology — Posted on 2021-02-06
3333 Osteomacs support osteoclast-mediated resorption and contribute to bone pathology in a postmenopausal osteoporosis mouse model
Batoon, L.; Millard, S. M.; Raggatt, L. J.; Wu, A. C.; Kaur, S.; Sun, L. W. H.; Williams, K.; Sandrock, C.; Ng, P. Y.; Bartnikowski, M.; Glatt, V.; Pavlos, N.; Pettit, A.
10.1101/2021.02.05.429872 — immunology — Posted on 2021-02-06
3334 Genome editing human primary T cells with microfluidic vortex shedding & CRISPR Cas9
Jarrell, J. A.; Sytsma, B. J.; Wilson, L. H.; Pan, F. L.; Lau, K. H. W. J.; Kirby, G. T. S.; Lievano, A. A.; Pawell, R. S.
10.1101/2020.02.26.960336 — immunology — Posted on 2021-02-06
3338 Thunor: Visualization and Analysis of High-Throughput Dose-response Datasets
Lubbock, A. L. R.; Harris, L. A.; Quaranta, V.; Tyson, D. R.; Lopez, C. F.
10.1101/530329 — pharmacology and toxicology — Posted on 2021-02-06
3339 Loss of HMCES is synthetic lethal with APOBEC activity in cancer cells
Biayna, J.; Garcia-Cao, I.; Alvarez, M. M.; Salvadores, M.; Espinosa-Carrasco, J.; McCullough, M.; Supek, F.; Stracker, T. H.
10.1101/2021.02.05.429803 — cancer biology — Posted on 2021-02-06
3340 Long-term antitumor CD8+ T cell immunity induced by endogenously engineered extracellular vesicles
Ferrantelli, F.; Manfredi, F.; Chiozzini, C.; Olivetta, E.; Giovannelli, A.; Leone, P.; Federico, M.
10.1101/2021.02.05.429897 — cancer biology — Posted on 2021-02-06
3341 Heterogeneous nuclear ribonucleoprotein K is overexpressed in acute myeloid leukemia and causes myeloproliferative disease in mice via altered Runx1 splicing
Aitken, M. J. L.; Malaney, P.; Zhang, X.; Herbrich, S. M.; Chan, L. E.; Ma, H.; Jacamo, R.; Duan, R.; Link, T. M.; Kornblau, S. M.; Kanagal-Shamanna, R.; Bueso-Ramos, C. E.; Post, S. M.
10.1101/2021.02.05.429385 — cancer biology — Posted on 2021-02-06
3342 FGFR2 fusion protein-driven mouse models of intrahepatic cholangiocarcinoma unveil a necessary role for Erk signaling
Cristinziano, G.; Porru, M.; Lamberti, D.; Buglioni, S.; Rollo, F.; Amoreo, C. A.; Manni, I.; Giannarelli, D.; Cristofoletti, C.; Russo, G.; Borad, M. J.; Grazi, G. L.; Diodoro, M. G.; Giordano, S.; Forcato, M.; Anastasi, S.; Leonetti, C.; Segatto, O.
10.1101/2020.05.20.106104 — cancer biology — Posted on 2021-02-06
3347 Drosophila Evolution over Space and Time (DEST) - A New Population Genomics Resource
Kapun, M.; Nunez, J. C. B.; Bogaerts-Marquez, M.; Murga-Moreno, J.; Paris, M.; Outten, J.; Coronado-Zamora, M.; Tern, C.; Rota-Stabelli, O.; Garcia Guerreiro, M. P. P.; Casillas, S.; Orengo, D. J.; Puerma, E.; Kankare, M.; Ometto, L.; Loeschcke, V. V.; Onder, B. S.; Abbott, J. K.; Schaeffer, S. W.; Rajpurohit, S.; Behrman, E. L.; Schou, M. F.; Merritt, T. J. S.; Lazzaro, B. P. B.; Glaser-Schmitt, A.; Argyridou, E.; Staubach, F.; Wang, Y.; Tauber, E.; Serga, S. V.; Fabian, D. K.; Dyer, K. A.; Wheat, C. W.; Parsch, J.; Grath, S.; Savic Veselinovic, M.; Stamenkovic-Radak, M.; Jelic, M.; Buendia-R
10.1101/2021.02.01.428994 — genomics — Posted on 2021-02-06
3349 Analysis of mitochondrial genome methylation using Nanopore single-molecule sequencing
Lueth, T.; Klein, C.; Schaake, S.; Tse, R.; Pereira, S.; Lass, J.; Sinkkonen, L.; Gruenewald, A.; Trinh, J.
10.1101/2021.02.05.429923 — genetics — Posted on 2021-02-06
3351 Enhanced genetic analysis of type 1 diabetes by selecting variants on both effect size and significance, and by integration with autoimmune thyroid disease
Crouch, D. J. M.; Inshaw, J. R. J.; Robertson, C. C.; Zhang, J.-Y.; Chen, W.-M.; Onengut-Gumuscu, S.; Cutler, A. J.; Sidore, C.; Cucca, F.; Pociot, F.; Concannon, P.; Rich, S. S.; Todd, J. A.
10.1101/2021.02.05.429962 — genetics — Posted on 2021-02-06
3352 Strong transgenerational effects but no genetic adaptation in zooplankton 24 years after an abrupt +10°C climate change
Pais-Costa, A. J.; Lievens, E. J. P.; Redon, S.; Sanchez, M. I.; Jabbour-Zahab, R.; Joncour, P.; Van Hoa, N.; Van Stappen, G.; Lenormand, T.
10.1101/2021.02.05.429921 — evolutionary biology — Posted on 2021-02-06
3353 The Goldilocks Effect: Female geladas in mid-sized groups have higher fitness
Tinsley Johnson, E.; Feder, J.; Bergman, T. J.; Lu, A.; Snyder-Mackler, N.; Beehner, J. C.
10.1101/348383 — evolutionary biology — Posted on 2021-02-06
3356 Characterization of a novel Fgf10CreERT2 knock-in mouse line targeting postnatal lung Fgf10 lineages
Chu, X.; Taghizadeh, S.; Vasquez-Armendariz, A. I.; Herold, S.; Lei, C.; Zhang, J. S.; El Agha, E.; Bellusci, S.
10.1101/2021.02.05.429562 — developmental biology — Posted on 2021-02-06
3359 Coordinate transcriptional and post-transcriptional repression of pro-differentiation genes maintains intestinal stem cell identity
Buddika, K.; Huang, Y.-T.; Ariyapala, I. S.; Butrum-Griffith, A.; Norrell, S. A.; OConnor, A. M.; Patel, V. K.; Rector, S. A.; Slovan, M.; Sokolowski, M.; Kato, Y.; Nakamura, A.; Sokol, N. S.
10.1101/2020.06.27.175398 — cell biology — Posted on 2021-02-06
3364 Subgenomic RNAs as molecular indicators of asymptomatic SARS-CoV-2 infection
Wong, C. H.; Ngan, C. Y.; Goldfeder, R. L.; Idol, J.; Kuhlberg, C.; Maurya, R.; Kelly, K.; Omerza, G.; Renzette, N.; Abreu, F. D.; Li, L.; Browne, F. A.; Liu, E. T.; Wei, C.-L.
10.1101/2021.02.06.430041 — microbiology — Posted on 2021-02-06
3365 Systematic measurement of combination drug landscapes to predict in vivo treatment outcomes for tuberculosis
Larkins-Ford, J.; Greenstein, T.; Van, N.; Degefu, Y. N.; Olson, M. C.; Sokolov, A.; Aldridge, B. B.
10.1101/2021.02.03.429579 — microbiology — Posted on 2021-02-06
3366 IL-1-driven stromal-neutrophil interaction in deep ulcers defines a pathotype of therapy non-responsive inflammatory bowel disease
Friedrich, M.; Pohin, M.; Jackson, M. A.; Korsunsky, I.; Bullers, S.; Rue-Albrecht, K.; Christoforidou, Z.; Santhananthan, D.; Ravindran, R.; Sanches Peres, R.; Sharpe, H.; Wei, K.; Watts, G. F. M.; Mann, E. H.; Geremia, A.; Thomas, T.; Attar, M.; Oxford IBD Cohort Investigators, ; Roche Fibroblast Network Consortium, ; McCuaig, S.; Thomas, L.; Collantes, E.; Uhlig, H. H.; Sansom, S. N.; Easton, A.; Raychaudhuri, S.; Travis, S. P.; Powrie, F. M.
10.1101/2021.02.05.429804 — immunology — Posted on 2021-02-06
3367 Fear in the mind's eye: Mental imagery can generate and regulate acquired differential fear conditioned reactivity
Greening, S. G.; Lee, T.-H.; Gregoire, L.; Burleigh, L.; Robinson, T.; Jiang, X.; Mather, M.; Kaplan, J.
10.1101/2021.02.04.429795 — neuroscience — Posted on 2021-02-06
3370 A novel RyR1 inhibitor prevents and rescues sudden death in a mouse model of malignant hyperthermia and heat stroke
Yamazawa, T.; Kobayashi, T.; Kurebayashi, N.; Konishi, M.; Noguchi, S.; Inoue, T.; Inoue, Y. U.; Nishino, I.; Mori, S.; Iinuma, H.; Manaka, N.; Kagechika, H.; Uryas, A.; Adams, J.; Lopez, J. R.; Liu, X.; Diggle, C.; Allen, P. D.; Kakizawa, S.; Ikeda, K.; Lin, B.; Ikemi, Y.; Nunomura, K.; Nakagawa, S.; Sakurai, T.; Murayama, T.
10.1101/2020.07.02.185520 — pharmacology and toxicology — Posted on 2021-02-06
3372 Engineering Threshold-Based Selection Systems
Pedone, K. H.; Gonzalez-Perez, V.; Leopold, L. E.; Der, C. J.; Cox, A. D.; Ahmed, S.; Reiner, D. J.
10.1101/2021.02.04.429784 — genetics — Posted on 2021-02-06
3373 Genetic Analysis of Right Heart Structure and Function in 40,000 People
Pirruccello, J. P.; Di Achille, P.; Nauffal, V.; Nekoui, M.; Friedman, S. N.; Klarqvist, M. D. R.; Chaffin, M. D.; Khurshid, S.; Roselli, C.; Batra, P.; Ng, K.; Lubitz, S. A.; Ho, J. E.; Lindsay, M. E.; Philippakis, A. A.; Ellinor, P. T.
10.1101/2021.02.05.429046 — genetics — Posted on 2021-02-06
3374 Real-time conversion of tissue-scale mechanical forces into an interdigitated growth pattern
Belteton, S. A.; Li, W.; Yanagisawa, M.; Afshar-Hatam, F.; Quinn, M. I.; Szymanski, M. K.; Marley, M. W.; Turner, J. A.; Szymanski, D. B.
10.1101/2021.02.06.428645 — cell biology — Posted on 2021-02-06
3376 The glycosphingolipid inhibitor eliglustat inhibits autophagy in osteoclasts to increase bone mass and reduce myeloma bone disease
Leng, H.; Zhang, H.; Li, L.; Zhang, S.; Wang, Y.; Ersek, A.; Morris, E.; Sezgin, E.; Lee, Y.-H.; Li, Y.; Mi, J.; Zhong, Q.; Edwards, C.; Simon, A. K.; Horwood, N. J.
10.1101/2021.02.05.429906 — cell biology — Posted on 2021-02-06
3377 A novel class of sulfur-containing aminolipids widespread in marine roseobacters
Smith, A.; Silvano, E.; Pauker, O.; Guillonneau, R.; Quareshy, M.; Murphy, A.; Mausz, M. A.; Stirrup, R.; Rihtman, B.; Ferretjans, M. A.; Brandsma, J.; Petersen, J.; Scanlan, D. J.; Chen, Y.
10.1101/2021.02.05.429882 — microbiology — Posted on 2021-02-06
3379 In vivo magnetic resonance spectroscopy of hyperpolarized pyruvate in a male guinea pig model of life-long Western diet consumption and non-alcoholic fatty liver disease development
Smith, L. M.; Pitts, C. B.; Friesen-Waldner, L. J.; Prabhu, N. H.; Mathers, K. E.; Sinclair, K. J.; Wade, T. P.; Regnault, T. R.; McKenzie, C. A.
10.1101/2021.02.05.429612 — biophysics — Posted on 2021-02-06
3381 LAMP3 is critical for surfactant homeostasis in mice
Lunding, L. P.; Krause, D.; Stichtenoth, G.; Stamme, C.; Lauterbach, N.; Hegermann, J.; Ochs, M.; Schuster, B.; Sedlacek, R.; Saftig, P.; Schwudke, D.; Wegmann, M.; Damme, M.
10.1101/2021.02.05.429758 — biochemistry — Posted on 2021-02-06
3382 A Mendelian randomization study of the role of lipoprotein subfractions in coronary artery disease
Zhao, Q.; Wang, J.; Miao, Z.; Zhang, N. R.; Hennessy, S.; Small, D. S.; Rader, D. J.
10.1101/691089 — genetics — Posted on 2021-02-06
3383 Macroscopic quantities of collective brain activity during wakefulness and anesthesia
Ponce-Alvarez, A.; Uhrig, L.; Deco, N.; Signorelli, C. M.; Kringelbach, M.; Jarraya, B.; Deco, G.
10.1101/2021.02.03.429578 — neuroscience — Posted on 2021-02-06
3384 Effects of LSD are differentially modulated in arrestin knockout mice
Rodriguiz, R. M.; Nadkarni, V.; Means, C. R.; Chiu, Y.-T.; Roth, B. L.; Wetsel, W. C.
10.1101/2021.02.04.429772 — neuroscience — Posted on 2021-02-06
3385 Differences in interactions between transmembrane domains tune the activation of metabotropic glutamate receptors
Thibado, J.; Tano, J.-Y.; Lee, J.; Salas-Estrada, L.; Provasi, D.; Strauss, A.; Marcelo Lamim Ribeiro, J.; Xiang, G.; Broichhagen, J.; Filizola, M.; Lohse, M.; Levitz, J.
10.1101/2021.02.04.429701 — neuroscience — Posted on 2021-02-06
3386 Cancer cells adapt FAM134B-BiP complex mediated ER-phagy to survive hypoxic stress
Chipurupalli, S.; Ganesan, R.; Martini, G.; Mele, L.; Kannan, E.; Namasivayam, V.; Desiderio, V.; Robinson, N.
10.1101/2021.02.05.429931 — cancer biology — Posted on 2021-02-06
3387 The Integrity of the Speciation Core Complex is necessary for centromeric binding and reproductive isolation in Drosophila
Lukacs, A.; Thomae, A. W.; Krueger, P.; Schauer, T.; Venkateswaran Venkatasubramani, A.; Kochanova, N. Y.; Aftab, W.; Choudhury, R.; Forne, I.; Imhof, A.
10.1101/2021.02.05.429932 — biochemistry — Posted on 2021-02-06
3388 Rampant tooth loss across 200 million years of frog evolution
Paluh, D. J.; Riddell, K.; Early, C. M.; Hantak, M. M.; Jongsma, G. F.; Keeffe, R. M.; Magalhaes Silva, F.; Nielsen, S. V.; Vallejo-Pareja, M. C.; Stanley, E. L.; Blackburn, D. C.
10.1101/2021.02.04.429809 — evolutionary biology — Posted on 2021-02-06
3391 Insights into the mechanisms of LOV domain color tuning from a set of high-resolution X-ray structures
Remeeva, A.; Nazarenko, V. V.; Kovalev, K.; Goncharov, I. M.; Yudenko, A.; Astashkin, R.; Gordeliy, V.; Gushchin, I.
10.1101/2021.02.05.429969 — biophysics — Posted on 2021-02-06
3392 Mechanically Transduced Immunosorbent Assay To Measure Protein-Protein Interactions
Petell, C. J.; Randene, K.; Pappas, M.; Sandoval, D.; Strahl, B.; Harrison, J. S.; Steimel, J. P.
10.1101/2021.02.05.429999 — biochemistry — Posted on 2021-02-06
3394 Sublingual allergen immunotherapy with recombinant dog allergens prevents airway hyperresponsiveness in a model of asthma marked by vigorous TH2 and TH17 cell responses
Stark, J. M.; Liu, J.; Tibbitt, C. A.; Christian, M.; Ma, J.; Wintersand, A.; Murrell, B.; Adner, M.; Gronlund, H.; Gafvelin, G.; Coquet, J. M.
10.1101/2021.02.04.429730 — immunology — Posted on 2021-02-06
3396 Primary tumor associated macrophages activate programs of invasion and dormancy in disseminating tumor cells.
Borriello, L.; Coste, A.; Sharma, V.; Karagiannis, G.; Lin, Y.; Wang, Y.; Ye, X.; Duran, C.; Chen, X.; Dalla, E.; Singh, D.; Oktay, M.; Condeelis, J.; Entenberg, D.
10.1101/2021.02.04.429798 — cancer biology — Posted on 2021-02-05
3397 Cryo-EM Structure of Bacterioferritin Nanocages Provides Insight into the Bio-mineralization of Ferritins
Jobichen, C.; Ying Chong, T.; Rattinam, R.; Basak, S.; Srinivasan, M.; Pandey, K. P.; Ngoc, T. B.; Jian, S.; Angayarkanni, J.; Sivaraman, J.
10.1101/2021.02.04.429857 — biophysics — Posted on 2021-02-05
3401 BiSulfite Bolt: A BiSulfite Sequencing Analysis Platform
Farrell, C.; Thompson, M.; Tosevska, A.; Oyetunde, A.; Pellegrini, M.
10.1101/2020.10.06.328559 — bioinformatics — Posted on 2021-02-05
3404 FAIRSCAPE: A Framework for FAIR and Reproducible Biomedical Analytics
Levinson, M. A.; Niestroy, J.; Al Manir, S.; Fairchild, K. D.; Lake, D. E.; Moorman, J. R.; Clark, T.
10.1101/2020.08.10.244947 — bioinformatics — Posted on 2021-02-05
3405 Automatic Landmark Detection of Human Back Surface from Depth Images via Deep Learning
Delgarmi, M.; Heravi, H.; Rahimpour Jounghani, A.; Shahrezie, A.; Ebrahimi, A.; Shamsi, M.
10.1101/2021.02.04.429842 — bioengineering — Posted on 2021-02-05
3406 Automatic Identification and Avoidance of Axon Bundle Activation for Epiretinal Prosthesis
Tandon, P.; Bhaskar, N.; Shah, N.; Madugula, S.; Grosberg, L. E.; Fan, V. H.; Hottowy, P.; Sher, A.; Litke, A. M.; Chichilnisky, E. J.; Mitra, S.
10.1101/2021.02.03.429317 — bioengineering — Posted on 2021-02-05
3407 Analytical Performance of a Standardized Kit for Mass Spectrometry-based Measurements of Human Glycosaminoglycans
Tamburro, D.; Bratulic, S.; Shameh, S. A.; Soni, N. K.; Bacconi, A.; Maccari, F.; Galeotti, F.; Mattsson, K.; Volpi, N.; Nielsen, J.; Gatto, F.
10.1101/2021.02.04.429694 — biochemistry — Posted on 2021-02-05
3408 13C tracer analysis identifies extensive recycling of endogenous CO2 in vivo
Duan, L.; Cooper, D. E.; Scheidemantle, G.; Locasale, J.; Kirsch, D. G.; Liu, X.
10.1101/2021.02.04.429777 — biochemistry — Posted on 2021-02-05
3411 Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis
Tian, R.; Abarientos, A.; Hong, J.; Hashemi, S. H.; Yan, R.; Draeger, N.; Leng, K.; Nalls, M. A.; Singleton, A. B.; Xu, K.; Faghri, F.; Kampmann, M.
10.1101/2020.06.27.175679 — genomics — Posted on 2021-02-05
3412 Insights into Mus musculus subspecies population structure across Eurasia revealed by whole-genome sequence analysis
Fujiwara, K.; Kawai, Y.; Moriwaki, K.; Takada, T.; Shiroishi, T.; Saitou, N.; Suzuki, H.; Osada, N.
10.1101/2021.02.05.429881 — genomics — Posted on 2021-02-05
3413 Identification of LINE retrotransposons and long non-coding RNAs expressed in the octopus brain
Petrosino, G.; Ponte, G.; Volpe, M.; Zarrella, I.; Langella, C.; Di Cristina, G.; Finaurini, S.; Russo, M. T.; Basu, S.; Musacchia, F.; Ristoratore, F.; Pavlinic, D.; Benes, V.; Ferrante, M. I.; Albertin, C.; Simakov, O.; Gustincich, S.; Fiorito, G.; Sanges, R.
10.1101/2021.01.24.427974 — genomics — Posted on 2021-02-05
3415 Bayesian modeling of skewed X inactivation ingenetically diverse mice identifies a novel Xce allele associated with copy number changes
Sun, K. Y.; Oreper, D. G.; Schoenrock, S. A.; McMullan, R.; Giusti-Rodriguez, P.; Zhabotynsky, V.; Miller, D. R.; Tarantino, L. M.; Pardo-Manuel de Villena, F.; Valdar, W.
10.1101/2020.11.13.380535 — genetics — Posted on 2021-02-05
3419 Ancient genomes reveal hybridisation between extinct short-faced bears and the extant spectacled bear (Tremarctos ornatus)
Salis, A. T.; Gower, G.; Schubert, B. W.; Soibelzon, L. H.; Heiniger, H.; Prieto, A.; Prevosti, F. J.; Meachen, J.; Cooper, A.; Mitchell, K. J.
10.1101/2021.02.05.429853 — evolutionary biology — Posted on 2021-02-05
3421 TRNP1 sequence, function and regulation co-evolve with cortical folding in mammals
Enard, W.; Hellmann, I.; Goetz, M.; Esgleas, M.; Huelsmann, M.; Kliesmete, Z.; Wange, L. E.; Vieth, B.; Radmer, J.; Geuder, J.; Richter, D.; Ohnuki, M.
10.1101/2021.02.05.429919 — evolutionary biology — Posted on 2021-02-05
3423 Evolution and connectivity influence the persistence and recovery of coral reefs under climate change in the Caribbean, Southwest Pacific, and Coral Triangle
McManus, L. C.; Forrest, D. L.; Tekwa, E. W.; Schindler, D. E.; Colton, M. A.; Webster, M. M.; Essington, T. E.; Palumbi, S. R.; Mumby, P. J.; Pinsky, M. L.
10.1101/2021.02.04.429453 — ecology — Posted on 2021-02-05
3428 Morphogenetic coupling leads to pattern emergence in the pre somitic mesoderm
Fulton, T.; Hwang, S.; Wang, Y.; Thomson, L.; Clark, B.; Verd, B.; Steventon, B.
10.1101/2021.02.05.429898 — developmental biology — Posted on 2021-02-05
3429 Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads
Belicova, L.; Repnik, U.; Delpierre, J.; Gralinska, E.; Seifert, S.; Valenzuela, J. I.; Morales-Navarrete, H. A.; Franke, C.; Raagel, H.; Shcherbinina, E.; Prikazchikova, T. P.; Koteliansky, V.; Vingron, M.; Kalaidzidis, Y.; Zatsepin, T.; Zerial, M.
10.1101/2020.12.31.424978 — cell biology — Posted on 2021-02-05
3431 Structural and molecular basis for Cardiovirus 2A protein as a viral gene expression switch
Hill, C. H.; Napthine, S.; Pekarek, L.; Kibe, A.; Firth, A. E.; Graham, S. C.; Caliskan, N.; Brierley, I.
10.1101/2020.08.11.245035 — molecular biology — Posted on 2021-02-05
3433 Spatio-temporal control of DNA replication by the pneumococcal cell cycle regulator CcrZ
Gallay, C.; Sanselicio, S.; Anderson, M. E.; Soh, Y. M.; Liu, X.; Stamsas, G. A.; Pelliciari, S.; van Raaphorst, R.; Denereaz, J.; Kjos, M.; Murray, H.; Gruber, S.; Grossman, A. D.; Veening, J.-W.
10.1101/775536 — microbiology — Posted on 2021-02-05
3438 Cognitive and GABAergic protection by hAPPSw,Ind and hTauVLW coexpression: a model of Non-Demented with Alzheimer's disease Neuropathology
Davila-Bouziguet, E.; Casoliba-Melich, A.; Targa-Fabra, G.; Galera-Lopez, L.; Ozaita, A.; Maldonado, R.; Delgado-Garcia, J. M.; Gruart, A.; Avila, J.; Soriano, E.; Pascual, M.
10.1101/2020.12.10.417907 — neuroscience — Posted on 2021-02-05
3442 Local projections of layer Vb-to-Va are more effective in lateral than in medial entorhinal cortex
Ohara, S.; Blankvoort, S.; Nair, R. R.; Nigro, M. J.; Nilssen, E. S.; Kentros, C.; Witter, M. P.
10.1101/2020.09.17.301002 — neuroscience — Posted on 2021-02-05
3449 What The Brain Does As We Speak
Forseth, K. J.; Pitkow, X.; Fischer-Baum, S.; Tandon, N.
10.1101/2021.02.05.429841 — neuroscience — Posted on 2021-02-05
3450 Neural Network Organization for Courtship Song Feature Detection in Drosophila
Baker, C. A.; McKellar, C.; Nern, A.; Dorkenwald, S.; Pacheco, D. A.; Pang, R.; Eckstein, N.; Funke, J.; Dickson, B. J.; Murthy, M.
10.1101/2020.10.08.332148 — neuroscience — Posted on 2021-02-05
3454 The Physcomitrium (Physcomitrella) patens PpKAI2L receptors for strigolactones and related compounds highlight MAX2 dependent and independent pathways
LOPEZ-OBANDO, M.; GUILLORY, A.; BOYER, F.-D.; CORNU, D.; HOFFMANN, B.; LE BRIS, P.; POUVREAU, J.-B.; DELAVAULT, P.; RAMEAU, C.; DE SAINT GERMAIN, A.; BONHOMME, S.
10.1101/2020.11.24.395954 — plant biology — Posted on 2021-02-05
3455 Cytoplasmic and nuclear Sw-5b NLR act both independently and synergistically to dictate full host defense against tospovirus infection
Chen, H.; Qian, X.; Chen, X.; Yang, T.; Feng, M.; Chen, J.; Cheng, R.; Hong, H.; Zheng, Y.; Mei, Y.; Shen, D.; Xu, Y.; Zhu, M.; Ding, X. S.; Tao, X.
10.1101/2020.12.24.424293 — plant biology — Posted on 2021-02-05
3456 The epoxyeicosatrienoic pathway is intact in endothelial and smooth muscle cells exposed to aldosterone excess
Brunnenkant, L.; Meng, Y.; Sun, J.; Gonzalez Marques, J.; Koletzko, B.; Mederos y Schnitzler, M.; Gudermann, T.; Williams, T. A.; Beuschlein, F.; Heinrich, D. A.; Adolf, C.; Reincke, M.; Schneider, H.
10.1101/2021.02.04.429624 — physiology — Posted on 2021-02-05
3460 CRISPR-Cas9 gene editing and rapid detection of gene-edited mutants using high-resolution melting in the apple scab fungus, Venturia inaequalis
Rocafort, M.; Arshed, S.; Hudson, D.; Singh, J.; Bowen, J. K.; Plummer, K. M.; Bradshaw, R. E.; Johnson, R. D.; Johnson, L. J.; Mesarich, C. H.
10.1101/2021.02.04.428760 — microbiology — Posted on 2021-02-05
3462 Modeling ex vivo tumor-infiltrating lymphocyte expansion from established solid malignancies
Knochelmann, H. M.; Rivera-Reyes, A. M.; Wyatt, M. M.; Smith, A. S.; Chamness, R.; Dwyer, C. J.; Bobian, M.; Rangel Rivera, G. O.; Horton, J. D.; Lilly, M.; Rubinstein, M. P.; Neskey, D. M.; Paulos, C. M.
10.1101/2021.02.04.429846 — immunology — Posted on 2021-02-05
3463 Oxazepam and cognitive reappraisal: a randomised experiment
Nilsonne, G.; Tamm, S.; Golkar, A.; Olsson, A.; Sörman, K.; Howner, K.; Kristiansson, M.; Ingvar, M.; Petrovic, P.
10.1101/656355 — neuroscience — Posted on 2021-02-05
3465 Nutritional Redundancy in Human Diet
Wang, X.-W.; Grodstein, F.; Bhupathiraju, S. N.; Sun, Q.; Zhang, X.; Hu, F.; Weiss, S. T.; Liu, Y.-Y.
10.1101/2021.02.04.429776 — systems biology — Posted on 2021-02-05
3466 Pharmacokinetics of Orally Administered GS-441524 in Dogs
Yan, V. C.; Khadka, S.; Arthur, K.; Ackroyd, J. J.; Georgiou, D. K.; Muller, F. L.
10.1101/2021.02.04.429674 — pharmacology and toxicology — Posted on 2021-02-05
3468 Targeting of TP53-independent cell cycle checkpoints overcomes FOLFOX resistance in Metastatic Colorectal Cancer
Behrenbruch, C.; Foroutan, M.; Lind, P.; Smith, J.; Grandin, M.; Cooper, B.; Shembrey, C.; Ramm, S.; Cowley, K.; Nikolic, I.; Liuu, J.; Cursons, J.; Millen, R.; Patch, A.-M.; Huntington, N. D.; Puisieux, A.; Michael, M.; Knowles, B.; Thomson, B. N.; Ramsay, R. G.; Grimmond, S. M.; Simpson, K.; Heriot, A. G.; Hollande, F.
10.1101/2021.02.04.429849 — cancer biology — Posted on 2021-02-05
3473 Caprin-1 binding to the critical stress granule protein G3BP1 is regulated by pH
Schulte, T.; Panas, M. D.; Wiliams, L.; Kedersha, N.; Fleck, J. S.; Tan, T. J. C.; Olsson, A.; Morro, A. M.; Hanke, L.; Nilvebrant, J.; Giang, K. A.; Nygren, P.-A.; Anderson, P.; Achour, A.; McInerney, G. M.
10.1101/2021.02.05.429362 — biochemistry — Posted on 2021-02-05
3474 Furin cleavage of the SARS-CoV-2 spike is modulated by O-glycosylation
Zhang, L.; Mann, M.; Syed, Z.; Reynolds, H. M.; Tian, E.; Samara, N. L.; Zeldin, D. C.; Tabak, L. A.; Ten Hagen, K. G.
10.1101/2021.02.05.429982 — biochemistry — Posted on 2021-02-05
3475 Serological Profile Of Specific Antibodies Against Dominant Antigens Of SARS-CoV-2 In Chilean COVID-19 Patients.
Cereceda, K.; Gonzalez-Stegmaier, R.; Briones, J. L.; Selman, C.; Aguirre, A.; Valenzuela-Nieto, G.; Caglevic, C.; Gazitua, R.; Rojas-Fernandez, A.; Villaroel-Espindola, F.
10.1101/2021.02.05.429566 — biochemistry — Posted on 2021-02-05
3476 Human brain mitochondrial-nuclear cross-talk is cell-type specific and is perturbed by neurodegeneration
Fairbrother-Browne, A.; Ali, A. T.; Reynolds, R. H.; Garcia-Ruiz, S.; Zhang, D.; Chen, Z.; Ryten, M.; Hodgkinson, A.
10.1101/2021.02.04.429781 — genomics — Posted on 2021-02-05
3477 BGvar - a comprehensive resource for blood group immunogenetics
Rophina, M.; Pandhare, K.; Jadhao, S.; Nagaraj, S. H.; Scaria, V.
10.1101/2021.02.04.429861 — genomics — Posted on 2021-02-05
3482 Protein glycosylation is essential for SARS-CoV-2 infection
Casas-Sanchez, A.; Romero-Ramirez, A.; Hargreaves, E.; Patterson, E. I.; Hughes, G. L.; Zech, T.; Acosta-Serrano, A.
10.1101/2021.02.05.429940 — microbiology — Posted on 2021-02-05
3483 On the robustness of inference of association with the gut microbiota in stool, swab and mucosal tissue samples
Sun, S.; Zhu, X.; Huang, X.; Murff, H. J.; Ness, R. M.; Seidner, D. L.; Sorgen, A.; Blakley, I.; Yu, C.; Dai, Q.; Azcarate-Peril, M. A.; Shrubsole, M. J.; Fodor, A. A.
10.1101/2021.02.04.429844 — microbiology — Posted on 2021-02-05
3484 High fiber, whole foods dietary intervention alters the human gut microbiome but not fecal short-chain fatty acids
Oliver, A.; Chase, A. B.; Weihe, C.; Orchanian, S. B.; Riedel, S. F.; Hendrickson, C.; Lay, M.; Massimelli Sewall, J.; Martiny, J. B.; Whiteson, K.
10.1101/2021.02.04.429869 — microbiology — Posted on 2021-02-05
3486 Post-infection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection
Dampalla, C.; Zheng, J.; Perera, K.; Wong, L. Y. R.; Meyerholz, D.; Nguyen, H.; Kashipathy, M.; Battaile, K.; Lovell, S.; Kim, Y.; Perlman, S.; Groutas, W.; Chang, K.-O.
10.1101/2021.02.05.429937 — microbiology — Posted on 2021-02-05
3488 Collaboration between the Fab and Fc contribute to maximal protection against SARS-CoV-2 in nonhuman primates following NVX-CoV2373 subunit vaccine with Matrix-M™ vaccination
Gorman, M. J.; Patel, N.; Guebre-Xabier, M.; Zhu, A.; Atyeo, C.; Pullen, K.; Loos, C.; Goez-Gazi, Y.; Carrion, R.; Tian, J.-H.; Yuan, D.; Bowman, K.; Zhou, B.; Maciejewski, S.; McGrath, M.; Logue, J.; Frieman, M.; Montefiori, D.; Mann, C.; Schendel, S.; Amanat, F.; Krammer, F.; Saphire, E. O.; Lauffenburger, D. A.; Greene, A. M.; Portnoff, A. D.; Massare, M. J.; Ellingsworth, L.; Glenn, G.; Smith, G.; Alter, G.
10.1101/2021.02.05.429759 — immunology — Posted on 2021-02-05
3489 SARS-CoV-2 ORF7b: is a bat virus protein homologue a major cause of COVID-19 symptoms?
Fogeron, M.-L.; Montserret, R.; Zehnder, J.; Nguyen, M.-H.; Dujardin, M.; Brigandat, L.; Cole, L.; Ninot-Pedrosa, M.; Lecoq, L.; Meier, B. H.; Bockmann, A.
10.1101/2021.02.05.428650 — biochemistry — Posted on 2021-02-05
3490 Tuberculostearic acid (TSA)-containing phosphatidylinositols as reliable marker to determine Mycobacterium tuberculosis bacterial burden
Brandenburg, J.; Heyckendorf, J.; Waldow, F.; Zehethofer, N.; Linnemann, L.; Gisch, N.; Karakose, H.; Reimann, M.; Kranzer, K.; Kalsdorf, B.; Sanchez-Carballo, P.; Weinkauf, M.; Scholz, V.; Malm, S.; Homolka, S.; Gaede, K. I.; Herzmann, C.; Schaible, U. E.; Hölscher, C.; Reiling, N.; Schwudke, D.
10.1101/2021.02.04.429149 — biochemistry — Posted on 2021-02-05
3491 Catching SARS-CoV-2 by sequence hybridization: a comparative analysis
Rehn, A.; Braun, P.; Knuepfer, M.; Woelfel, R.; Antwerpen, M. H.; Walter, M. C.
10.1101/2021.02.05.429917 — genomics — Posted on 2021-02-05
3493 A comparative study of isothermal nucleic acid amplification methods for SARS-CoV-2 detection at point-of-care
Tran, D. H.; Hoang, Q. C.; Tran, H. T.; Le, U. P.; Do, H. D. K.; Bui, L. M.; Nguyen, D. H.; Hoang, T. L.; Nguyen, T. T. T.; Nguyen, H. A.; Nguyen, T. H.; Cao, M. T.; Vu, V. V.; Phung, H. T. T.
10.1101/2020.05.24.113423 — molecular biology — Posted on 2021-02-05
3494 Bone Marrow-Derived AXL Tyrosine Kinase Promotes Mitogenic Crosstalk and Cardiac Allograft Vasculopathy
Glinton, K.; DeBerge, M.; Fisher, E.; Schroth, S.; Sinha, A.; Wang, J.-J.; Wasserstrom, J. A.; Ansari, M. J.; Zhang, Z. J.; Feinstein, M.; Leventhal, J.; Forbess, J.; Lomasney, J.; Luo, X.; Thorp, E. B.
10.1101/2021.02.04.429773 — immunology — Posted on 2021-02-05
3495 Discovery and Functional Characterization of Pro-growth Enhancers in Human Cancer Cells
Chen, P.; Fiaux, P.; Li, B.; Zhang, K.; Kubo, N.; Jiang, S.; Hu, R.; Wu, S.; Wang, M.; Wang, W.; McVicker, G. P.; Mischel, P.; Ren, B.
10.1101/2021.02.04.429675 — cancer biology — Posted on 2021-02-05
3499 Brain transcriptional regulatory architecture and schizophrenia etiology converge between East Asian and European ancestral populations
Liu, S.; Chen, Y.; Wang, F.; Jiang, Y.; Duan, F.; Xia, Y.; Ning, Z.; Li, M.; Qiu, W.; Ma, C.; Yan, X.; Bao, A.; Dai, J.; Kopp, R. F.; Kuney, L.; Huang, J.; Xu, S.; Tang, B.; Liu, C.; Chen, C.
10.1101/2021.02.04.922880 — genetics — Posted on 2021-02-05
3500 Functional traits of carabid beetles reveal seasonal variation in community assembly in annual crops
Marrec, R.; Gross, N.; Badenhausser, I.; Dupeyron, A.; Caro, G.; Bretagnolle, V.; Roncoroni, M.; Gauffre, B.
10.1101/2021.02.04.429696 — ecology — Posted on 2021-02-05
3502 Sublingual allergen immunotherapy with recombinant dog allergens prevents airway hyperresponsiveness in a model of asthma marked by vigorous TH2 and TH17 cell responses
Coquet, J. M.; Stark, J. M.; Liu, J.; Tibbitt, C. A.; Christian, M.; Ma, J.; Wintersand, A.; Murrell, B.; Adner, M.; Gronlund, H.; Gafvelin, G.
10.1101/2021.02.04.429730 — immunology — Posted on 2021-02-05
3503 Somatosensory innervation of healthy human oral tissues
Moayedi, Y.; Michlig, S.; Park, M.; Koch, A.; Lumpkin, E. A.
10.1101/2021.02.03.429664 — neuroscience — Posted on 2021-02-05
3504 Psilocybin-induced changes in brain network integrity and segregation correlate with plasma psilocin level and psychedelic experience
Madsen, M. K.; Stenbaek, D. S.; Arvidsson, A.; Armand, S.; Marstrand-Jorgensen, M. R.; Johansen, S. S.; Linnet, K.; Ozenne, B.; Knudsen, G. M.; Fisher, P. M.
10.1101/2021.02.03.429325 — neuroscience — Posted on 2021-02-05
3506 Neuron-derived extracellular vesicles extracted from plasma show altered size and miRNA cargo as a function of antidepressant drug response
Saeedi, S.; Nagy, C.; Ibrahim, P.; Theroux, J.-F.; Wakid, M.; Fiori, L.; Yang, J.; Rotzinger, S.; Foster, J. A.; Mechawar, N.; Kennedy, S. H.; Turecki, G.
10.1101/2021.02.03.429557 — neuroscience — Posted on 2021-02-05
3509 Pulsed Focal ultrasound as a non-invasive method to deliver exosomes in the brain/stroke
Alptekin, A.; Khan, M. B.; Ara, R.; Rashid, M. H.; Kong, F.; Parvin, M.; Frank, J. A.; Chopra, R.; Dhandapani, K.; Arbab, A. S.
10.1101/2021.02.03.429621 — neuroscience — Posted on 2021-02-05
3518 The prevalence, predominance, and metabolic potentials of Candidatus Prochlorobium terpiosii in the coral-killing sponge, Terpios hoshinota
Chen, Y.-H.; Chen, H.-J.; Yang, C.-Y.; Shiu, J.-H.; Hoh, D. Z.; Chiang, P.-W.; Chow, W. S.; Chen, C. A.; Shih, T.-H.; Lin, S.-H.; Yang, C.-M.; Reimer, J. D.; Hirose, E.; Iskandar, B. H.; Huang, H.; Schupp, P. J.; Tan, C. H. J.; Yamashiro, H.; Liao, M.-H.; Tang, S.-L.
10.1101/2021.02.04.429686 — ecology — Posted on 2021-02-05
3520 Interleukin-33 regulates metabolic reprogramming of the retinal pigment epithelium in response to immune stressors.
Scott, L. M.; Vincent, E. E.; Hudson, N.; Neal, C.; Jones, N.; Lavelle, E.; Campbell, M.; Halestrap, A.; Dick, A. D.; Theodoropoulou, S.
10.1101/2021.02.04.429634 — immunology — Posted on 2021-02-05
3521 PML-Dependent Memory of Type I Interferon Treatment Results in a Restricted Form of HSV Latency
Suzich, J. B.; Cuddy, S. R.; Baidas, H.; Dochnal, S.; Ke, E.; Babnis, A.; Boutell, C.; Cliffe, A. R.
10.1101/2021.02.03.429616 — immunology — Posted on 2021-02-05
3522 New lessons on TDP-43 from the killifish N. furzeri
Louka, A.; Bagnoli, S.; Rupert, J.; Esapa, B.; Tartaglia, G. G.; Cellerino, A.; Pastore, A.; Terzibasi Tozzini, E.
10.1101/2021.02.04.429704 — neuroscience — Posted on 2021-02-05
3528 Sublayer- and cell-type-specific neurodegenerative transcriptional trajectories in hippocampal sclerosis
Cid, E.; Marquez-Galera, A.; Valero, M.; Gal, B.; Medeiros, D. C.; Navarron, C. M.; Ballesteros-Esteban, L.; Reig-Viader, R.; Morales, A. V.; Fernandez-Lamo, I.; Gomez-Dominguez, D.; Sato, M.; Hayashi, Y.; Bayes, A.; Barco, A.; Lopez-Atalaya, J. P.; de la Prida, L. M.
10.1101/2021.02.03.429560 — neuroscience — Posted on 2021-02-05
3529 Human islet expression levels of Prostaglandin E2 synthetic enzymes, but not prostaglandin EP3 receptor, are positively correlated with markers of β-cell function and mass in non-diabetic obesity
Truchan, N. A.; Fenske, R. J.; Sandhu, H. K.; Weeks, A. M.; Patibandla, C.; Reuter, A.; Harrington, J. M.; Brill, A. L.; Peter, D. C.; Nall, R.; Daniels, M.; Pabich, S.; Punt, M.; Davis, D. B.; Kimple, M. E.
10.1101/2021.02.03.429205 — pharmacology and toxicology — Posted on 2021-02-05
3530 Fentanyl binds to the mu-opioid receptor via the lipid membrane and transmembrane helices
Sutcliffe, K. J.; Corey, R. A.; Charlton, S. J.; Sessions, R. B.; Henderson, G.; Kelly, E.
10.1101/2021.02.04.429703 — pharmacology and toxicology — Posted on 2021-02-05
3532 Quantifying full-length circular RNAs in cancer
Yu, K. H.-O.; Shi, C. H.; Wang, B.; Chow, S. H.-C.; Chung, G. T.-Y.; Tan, K.-E.; Lim, Y.-Y.; Tsang, A. C.-M.; Lo, K.-W.; Yip, K. Y.
10.1101/2021.02.04.429722 — bioinformatics — Posted on 2021-02-05
3538 BioDynaMo: a general platform for scalable agent-based simulation
Breitwieser, L.; Hesam, A.; de Montigny, J.; Vavourakis, V.; Iosif, A.; Jennings, J.; Kaiser, M.; Manca, M.; Di Meglio, A.; Al-Ars, Z.; Rademakers, F.; Mutlu, O.; Bauer, R.
10.1101/2020.06.08.139949 — systems biology — Posted on 2021-02-05
3539 Development of a highly sensitive bioanalytical assay for the quantification of favipiravir.
Curley, P.; Neary, M.; Arshad, U.; Tatham, L.; Pertinez, H.; Box, H.; Rajoli, R. K. R.; Valentijn, A.; Sharp, J.; Rannard, S.; Owen, A.
10.1101/2021.02.03.429628 — pharmacology and toxicology — Posted on 2021-02-05
3540 Maize inbred line B96 is the source of large-effect loci for resistance to generalist but not specialist spider mites
Bui, H.; Greenhalgh, R.; Gill, G. S.; Ji, M.; Kurlovs, A. H.; Ronnow, C.; Lee, S.; Ramirez, R. A.; Clark, R. M.
10.1101/2021.02.04.429847 — genetics — Posted on 2021-02-05
3541 Preprinting the COVID-19 pandemic
Fraser, N.; Brierley, L.; Dey, G.; Polka, J. K.; Palfy, M.; Nanni, F.; Coates, J. A.
10.1101/2020.05.22.111294 — scientific communication and education — Posted on 2021-02-05
3543 The chicken or the egg? Plastome evolution and a novel loss of the inverted repeat in papilionoid legumes
Lee, C.; Choi, I.-S.; Cardoso, D.; de Lima, H. C.; Wojciechowski, M. F.; Jansen, R. K.; Ruhlman, T. A.
10.1101/2021.02.04.429812 — plant biology — Posted on 2021-02-05
3545 The evolutionary making of SARS-CoV-2
Iruegas Lopez, R.; Dosch, J.; Sikora, M.; Hummer, G.; Covino, R.; Ebersberger, I.
10.1101/2021.01.29.428808 — evolutionary biology — Posted on 2021-02-05
3547 Development of the entorhinal cortex occurs via parallel lamination during neurogenesis.
Liu, Y.; Bergmann, T.; Mori, Y.; Peralvo Vidal, J. M.; Pihl, M.; Vasistha, N. A.; Dybdahl Thomsen, P.; Seemann, S. E.; Gorodkin, J.; Hyttel, P.; Khodosevich, K.; Witter, M.; Hall, V. J.
10.1101/2021.02.05.429755 — developmental biology — Posted on 2021-02-05
3548 Characterisation of protease activity during SARS-CoV-2 infection identifies novel viral cleavage sites and cellular targets for drug repurposing
Meyer, B.; Chiaravalli, J.; Gellenoncourt, S.; Brownridge, P.; Bryne, D. P.; Daly, L. A.; Walter, M.; Agou, F.; Chakrabarti, L. A.; Craik, C. S.; Eyers, C. E.; Eyers, P. A.; Gambin, Y.; Sierecki, E.; Verdin, E.; Vignuzzi, M.; Emmott, E.
10.1101/2020.09.16.297945 — microbiology — Posted on 2021-02-05
3551 ARGONAUTE10 is required for cell fate specification and the control of formative cell divisions in the Arabidopsis root meristem
El Arbi, N.; Schurholz, A.-K.; Schiffner, A.; Hidalgo Prados, I.; Bohme, F.; Wenzl, C.; Zhao, X.; Zeng, J.; Lohmann, J. U.; Wolf, S.
10.1101/2021.02.05.429893 — plant biology — Posted on 2021-02-05
3552 Tropism of SARS-CoV-2 in commonly used laboratory cell lines and their proteomic landscape during infection
Saccon, E.; Chen, X.; Mikaeloff, F.; Rodriguez, J. E.; Szekely, L.; Vinhas, B. S.; Krishnan, S.; Byrareddy, S.; Frisan, T.; Vegvari, A.; Mirazimi, A.; Neogi, U.; Gupta, S.
10.1101/2020.08.28.271684 — microbiology — Posted on 2021-02-05
3553 Transcriptomic profiling of atrial fibrillation canine models at disease onset
Leblanc, F. J. A.; Vahdati Hassani, F.; Qi, X.; Liesinger, L.; Naud, P.; Birner-Gruenberger, R.; Lettre, G.; Nattel, S.
10.1101/2021.02.04.429512 — genomics — Posted on 2021-02-05
3555 The epigenetic landscape in purified myonuclei from fast and slow muscles
Bengtsen, M.; Winje, I. M.; Eftestoel, E.; Landskron, J.; Sun, C.; Domanska, D.; Millay, D.; Meza-Zepeda, L.; Gundersen, K.
10.1101/2021.02.04.429545 — physiology — Posted on 2021-02-05
3558 Lymphatic PD-L1 expression restricts tumor-specific CD8+ T cell responses
Cousin, N.; Cap, S.; Dihr, M.; Tacconi, C.; Detmar, M.; Dieterich, L.
10.1101/2020.10.22.350934 — immunology — Posted on 2021-02-05
3559 ERAP2 increases the abundance of a peptide submotif highly selective for the Birdshot Uveitis-associated HLA-A29
Venema, W.; Hiddingh, S.; de Boer, J. H.; Claas, F.; Mulder, A.; Hollander, A. D.; Stratikos, E.; Sarkizova, S.; Veken, L. v. d.; Janssen, G.; Veelen, P. v.; Kuiper, J. J.
10.1101/2020.08.14.250654 — immunology — Posted on 2021-02-05
3560 Cholesterol recognition motifs in the transmembrane domain of the tyrosine kinase receptor family: the case for TRKB
Cannarozzo, C.; Fred, S. M.; Girych, M.; Biojone, C.; Enkavi, G.; Laukkanen, L.; Rog, T.; Vattulainen, I.; Casarotto, P. C.; Castren, E.
10.1101/734012 — neuroscience — Posted on 2021-02-05
3561 Plasticity of body axis polarity in Hydra regeneration under constraints
Livshits, A.; Garion, L.; Maroudas-Sacks, Y.; Shani-Zerbib, L.; Braun, E.; Keren, K.
10.1101/2021.02.04.429818 — biophysics — Posted on 2021-02-05
3563 A New 'Comprehensive' Annotation of Leucine-Rich Repeat-Containing Receptors in Rice
Gottin, C.; Dievart, A.; Summo, M.; Droc, G.; Perin, C.; Ranwez, V.; Chantret, N.
10.1101/2021.01.29.428842 — genomics — Posted on 2021-02-05
3567 Genomic surveillance framework and global population structure for Klebsiella pneumoniae
Lam, M. M.; Wick, R. R.; Watts, S. C.; Cerdeira, L. T.; Wyres, K. L.; Holt, K. E.
10.1101/2020.12.14.422303 — genomics — Posted on 2021-02-05
3568 Ancestral mitochondrial apparatus derived from the bacterial type II secretion system
Horvathova, L.; Zarsky, V.; Panek, T.; Derelle, R.; Pyrih, J.; Motyckova, A.; Klapstova, V.; Vinopalova, M.; Markova, L.; Voleman, L.; Klimes, V.; Petru, M.; Vaitova, Z.; Cepicka, I.; Hryzakova, K.; Harant, K.; Gray, M. W.; Chami, M.; Guilvout, I.; Francetic, O.; Lang, B. F.; Vlcek, C.; Tsaousis, A. D.; Elias, M.; Dolezal, P.
10.1101/790865 — evolutionary biology — Posted on 2021-02-05
3569 The scaffold protein IQGAP1 links heat-induced stress signals to alternative splicing regulation in gastric cancer cells
Birladeanu, A.; Rogalska, M.; Potiri, M.; Papadaki, V.; Andreadou, M.; Kontoyiannis, D. L.; Lewis, J. D.; Erpapazoglou, Z.; Kafasla, P.
10.1101/2020.05.11.089656 — molecular biology — Posted on 2021-02-05
3570 Integrated tapered fibertrode for simultaneous control and readout of neural activity over small brain volumes with reduced light-induced artefacts
Spagnolo, B.; Peixoto, R.; Sileo, L.; Pisanello, M.; Pisano, F.; Assad, J. A.; Sabatini, B. L.; DeVittorio, m.; Pisanello, F.
10.1101/2020.07.31.226795 — neuroscience — Posted on 2021-02-05
3571 The immunosuppression of macrophages underlies the cardioprotective effects of catestatin (CST)
Ying, W.; Tang, K.; Avolio, E.; Schilling, J. M.; Pasqua, T.; Liu, M. A.; Cheng, H.; Gao, H.; Zhang, J.; Mahata, S.; Ko, M. S.; Bandyopadhyay, G. K.; Das, S.; Roth, D. M.; Sahoo, D.; Webster, N. J.; Sheikh, F.; Ghosh, G.; Patel, H. H.; Ghosh, P.; Bogaart, G. v. d.; Mahata, S. K.
10.1101/2020.05.12.092254 — physiology — Posted on 2021-02-04
3573 Genomic regions associated with Mycoplasma ovipneumoniae presence in nasal secretions of domestic sheep.
Mousel, M. R.; White, S. N.; Herndon, M. K.; Herndon, D. R.; Taylor, J. B.; Becker, G. M.; Murdoch, B. M.
10.1101/2021.02.04.429710 — genetics — Posted on 2021-02-04
3574 Follow-up of a hospital cohort during the first 3,530 suspected cases of COVID-19 in Sao Jose do Rio Preto, Sao Paulo, Brazil
Pacca, C. C.; Zini, N.; Versiani, A.; Lobl, E.; Milhim, B.; Campos, G.; Moraes, M.; dos Santos, T.; Dourado, F.; Moraes, B.; Rocha, L.; dos Santos, A.; Ruiz, L.; da Silva, G.; Nicesio, R.; Queiroz, F.; Salomao, M. L.; da Silva, N.; Negri, A.; Nogueira, M.; Estofolete, C.
10.1101/2021.02.04.429711 — molecular biology — Posted on 2021-02-04
3575 Chronic effects of short-term aerobic and anaerobic physical training on the ventral prostate of adult rats
Borges, R. M. R.; da Rocha, E. S.; de Andrade, E. M.; Nazare, N. E. d. S.; Araujo, P. A. O.; Cembraneli, P. N.; Ruiz, T. F. R.; Colleta, S. J.; Carlos, C. P.; Marques, V. B.; Taboga, S. R.; Gomes, F. d. C.; de Melo-Neto, J. S.
10.1101/2021.02.04.429709 — molecular biology — Posted on 2021-02-04
3577 Ventral hippocampus mediates the context-dependence of two-way signaled avoidance in male rats
Oleksiak, C. R.; Ramanathan, K. R.; Miles, O. W.; Perry, S. J.; Maren, S.; Moscarello, J. M.
10.1101/2021.02.04.429792 — neuroscience — Posted on 2021-02-04
3580 Nonsense-mediated decay is highly stable across individuals and tissues.
Teran, N. A.; Nachun, D.; Eulalio, T.; Ferraro, N. M.; Smail, C.; Rivas, M. A.; Montgomery, S. B.
10.1101/2021.02.03.429654 — genomics — Posted on 2021-02-04
3581 New loci and neuronal pathways for resilience to heat stress in animals
Cheruiyot, E. K.; Haile-Mariam, M.; Cocks, B. G.; MacLeod, I. M.; Xiang, R.; Pryce, J. E.
10.1101/2021.02.04.429719 — genomics — Posted on 2021-02-04
3584 Proximity proteomics in a marine diatom reveals a putative cell surface-to-chloroplast iron trafficking pathway
Turnsek, J.; Brunson, J. K.; Martinez Viedma, M. d. P.; Deerinck, T. J.; Horak, A.; Obornik, M.; Bielinski, V. A.; Allen, A. E.
10.1101/806539 — cell biology — Posted on 2021-02-04
3585 {-}Cellular and biochemical response to chaperone versus substrate reduction therapies in neuropathic Gaucher disease{-}
Ivanova, M. M.; Dao, J.; kasaci, N.; Adewale, B.; Nazari, S.; Noll, L.; Fikry, J.; Sanati, A. H.; Goker-Alpan, O.
10.1101/2021.02.04.429713 — molecular biology — Posted on 2021-02-04
3586 Species-resolved sequencing of low-biomass microbiomes by 2bRAD-M
Sun, Z.; Huang, S.; Zhu, P.; Tzehau, L.; Zhao, H.; Lv, J.; Zhang, R.; Zhou, L.; Niu, Q.; Wang, X.; Zhang, M.; Jing, G.; Bao, Z.; Liu, J.; Wang, S.; Xu, J.
10.1101/2020.12.01.405647 — microbiology — Posted on 2021-02-04
3587 Role of the transcriptional regulator SP140 in resistance to bacterial infections via repression of type I interferons
Ji, D. X.; Witt, K. C.; Kotov, D. I.; Margolis, S. R.; Louie, A.; Chevee, V.; Chen, K. J.; Dhaliwal, H. S.; Lee, A. Y.; Zamboni, D. S.; Kramnik, I.; Portnoy, D. A.; Darwin, K. H.; Vance, R. E.
10.1101/2020.01.07.897553 — immunology — Posted on 2021-02-04
3592 Mechanoreceptor synapses in the brainstem shape the central representation of touch
Lehnert, B. P.; Santiago, C.; Huey, E. L.; Emanuel, A. J.; Renauld, S.; Africawala, N.; Alkislar, I.; Zheng, Y.; Bai, L.; Koutsioumpa, C.; Hong, J. T.; Magee, A. R.; Harvey, C. D.; Ginty, D. D.
10.1101/2021.02.02.429463 — neuroscience — Posted on 2021-02-04
3593 Primary tumor associated macrophages activate programs of invasion and dormancy in disseminating tumor cells.
Borriello, L.; Coste, A.; Sharma, V.; Karagiannis, G.; Lin, Y.; Wang, Y.; Ye, X.; Duran, C.; Chen, X.; Dalla, E.; Singh, D.; Oktay, M.; Condeelis, J.; Entenberg, D.
10.1101/2021.02.04.429798 — cancer biology — Posted on 2021-02-04
3594 Perturbation of BRMS1 interactome reveals pathways that impact cell migration
Zimmermann, R. C.; Sardiu, M. E.; Manton, C. A.; Miah, M. S.; Banks, C. A.; Adams, M. K.; Koestler, D. C.; Washburn, M. P.; Welch, D. R.
10.1101/2021.02.04.429764 — cancer biology — Posted on 2021-02-04
3595 Synergistic Cytotoxicity Between Cold Atmospheric Plasma and Pyrazolopyrimidinones Against Glioblastoma Cells
He, Z.; Charleton, C.; Devine, R.; Kelada, M.; Walsh, J. M. D.; Conway, G.; Gunes, S.; Mondala, J. R. M.; Tian, F.; Tiwari, B.; Kinsella, G. K.; Malone, R.; O'Shea, D.; Devereux, M.; Wang, W.; Cullen, P. J.; Stephens, J. C.; Curtin, J. F.
10.1101/2021.02.04.429831 — cancer biology — Posted on 2021-02-04
3598 Elucidation of global and local epidemiology of Salmonella Enteritidis through multilevel genome typing
Luo, L.; Payne, M.; Kaur, S.; Hu, D.; Cheney, L.; Octavia, S.; Wang, Q.; Tanaka, M. M.; Sintchenko, V.; Lan, R.
10.1101/2020.06.30.169953 — genomics — Posted on 2021-02-04
3599 Substantial somatic genomic variation and selection for BCOR mutations in human induced pluripotent stem cells
Rouhani, F. J.; Zou, X.; Danecek, P.; Dias Amarante, T.; Koh, G.; Wu, Q.; Memari, Y.; Durbin, R.; Martincorena, I.; Bassett, A. R.; Gaffney, D.; Nik-Zainal, S.
10.1101/2021.02.04.429731 — genomics — Posted on 2021-02-04
3601 High-throughput miRNA-sequencing of the human placenta: expression throughout gestation
Gonzalez, T. L.; Eisman, L. E.; Joshi, N. V.; Flowers, A. E.; Wu, D.; Wang, Y.; Santiskulvong, C.; Tang, J.; Buttle, R. A.; Sauro, E.; Clark, E. L.; DiPentino, R.; Jefferies, C. A.; Chan, J. L.; Lin, Y.; Zhu, Y.; Afshar, Y.; Tseng, H.-R.; Taylor, K.; Williams, J.; Pisarska, M. D.
10.1101/2021.02.04.429392 — developmental biology — Posted on 2021-02-04
3603 Site-specific O-glycosylation analysis of SARS-CoV-2 spike protein produced in insect and human cells
Bagdonaite, I.; Thompson, A. J.; Wang, X.; Soegaard, M.; Fougeroux, C.; Frank, M.; Diedrich, J. K.; Yates, J. R.; Salanti, A.; Vakhrushev, S. Y.; Paulson, J. C.; Wandall, H. H.
10.1101/2021.02.03.429627 — molecular biology — Posted on 2021-02-04
3605 Prioritization of antimicrobial targets by CRISPR-based oligo recombineering
Benns, H. J.; Storch, M.; Falco, J.; Fisher, F. R.; Alves, E.; Wincott, C. J.; Baum, J.; Baldwin, G. S.; Weerapana, E.; Tate, E. W.; Child, M. A.
10.1101/2021.02.04.429737 — microbiology — Posted on 2021-02-04
3606 Microbiota analysis of rural and urban surface waters and sediments in Bangladesh identifies human waste as driver of antibiotic resistance
McInnes, R. S.; uz-Zaman, M. H.; Alam, I. T.; Ho, S. F. S.; Moran, R. A.; Clemens, J. D.; Islam, M. S.; van Schaik, W.
10.1101/2021.02.04.429629 — microbiology — Posted on 2021-02-04
3607 An extracellular redox signal triggers calcium release and impacts the asexual development of Toxoplasma gondii
Alves, E.; Benns, H. J.; Magnus, L.; Dominicus, C.; Dobai, T.; Blight, J.; Wincott, C. J.; Child, M. A.
10.1101/2021.02.04.429728 — microbiology — Posted on 2021-02-04
3608 Genome-Wide CRISPR Screening Identifies BRD9 as a Druggable Component of Interferon-Stimulated Gene Expression and Antiviral Activity
Börold, J.; Eletto, D.; Busnadiego, I.; Mair, N. K.; Moritz, E.; Schiefer, S.; Schmidt, N.; Petric, P. P.; Wong, W. W.-L.; Schwemmle, M.; Hale, B. G.
10.1101/2021.02.04.429732 — immunology — Posted on 2021-02-04
3609 Glutamatergic dysfunction precedes neuron loss in cerebral organoids with MAPT mutation.
Bowles, K. R.; Silva, M. C.; Whitney, K.; Bertucci, T.; Garza, J.; Boles, N. C.; Strang, K. H.; Mahali, S.; Marsh, J. A.; Chen, C.; Pugh, D. A.; Liu, Y.; Berlind, J. E.; Lai, J. D.; Goderie, S. K.; Chowdhury, R.; Lotz, S.; Lane, K.; Onanuga, K.; Karch, C.; Ichida, J.; Crary, J. F.; Haggarty, S. J.; Goate, A. M.; Temple, S.
10.1101/2021.02.03.429623 — neuroscience — Posted on 2021-02-04
3613 Dissecting Response to Cancer Immunotherapy by Applying Bayesian Network Analysis to Flow Cytometry Data
Rodin, A. S.; Gogoshin, G.; Hilliard, S.; Wang, L.; Egelston, C.; Rockne, R. C.; Chao, J.; Lee, P. P.
10.1101/2020.06.14.151100 — systems biology — Posted on 2021-02-04
3616 High Affinity Chimeric Antigen Receptor with Cross-Reactive scFv to Clinically Relevant EGFR Oncogenic Isoforms
Thokala, R.; Binder, Z. A.; Zhang, L.; Zhang, J. V.; Zhang, D. Y.; Milone, M. C.; Ming, G.-L.; Song, H.; O'Rourke, D. M.
10.1101/2021.02.04.429797 — cancer biology — Posted on 2021-02-04
3618 Missing the sweet spot: one of the two N-glycans on human Gb3/CD77 synthase curtails its activity
Mikolajczyk, K.; Bereznicka, A.; Szymczak-Kulus, K.; Haczkiewicz-Lesniak, K.; Szulc, B.; Olczak, M.; Rossowska, J.; Majorczyk, E.; Kapczynska, K.; Bovin, N. V.; Lisowska, M.; Kaczmarek, R.; Miazek, A.; Czerwinski, M.
10.1101/2021.02.04.429793 — biochemistry — Posted on 2021-02-04
3619 Genetically independent phenotype analysis identifies LPA and VCAM1 as drug targets for human ageing
Timmers, P. R. H. J.; Tiys, E. S.; Sakaue, S.; Akiyama, M.; Kiiskinen, T. T. J.; Zhou, W.; Hwang, S.-J.; Yao, C.; The Biobank Japan Project, ; FinnGen Study, ; Deelen, J.; Levy, D.; Ganna, A.; Kamatani, Y.; Okada, Y.; Joshi, P. K.; Wilson, J. F.; Tsepilov, Y. A.
10.1101/2021.01.22.427837 — genomics — Posted on 2021-02-04
3623 Sensory cilia act as a specialized venue for regulated EV biogenesis and signaling
Wang, J.; Nikonorova, I. A.; Silva, M. S.; Walsh, J. D.; Tilton, P. E.; Gu, A.; Barr, M. M.
10.1101/2021.02.04.429799 — cell biology — Posted on 2021-02-04
3624 Virome composition in marine fish revealed by meta-transcriptomics
Geoghegan, J. L.; Di Giallonardo, F.; Wille, M.; Ortiz-Baez, A. S.; Costa, V. A.; Ghaly, T.; Mifsud, J. C.; Turnbull, O. M.; Bellwood, D. R.; Williamson, J. E.; Holmes, E. C.
10.1101/2020.05.06.081505 — microbiology — Posted on 2021-02-04
3627 Deficits in Behavioral and Neuronal Pattern Separation in Temporal Lobe Epilepsy
Madar, A. D.; Pfammatter, J. A.; Bordenave, J.; Plumley, E. I.; Ravi, S.; Cowie, M.; Wallace, E. P.; Hermann, B. P. D.; Maganti, R. K.; Jones, M. V.
10.1101/2020.02.13.948364 — neuroscience — Posted on 2021-02-04
3634 Ocular elongation and retraction in foveated reptiles
Rasys, A. M.; Pau, S. H.; Irwin, K. E.; Luo, S.; Trainor, P. A.; Menke, D. B.; Lauderdale, J. D.
10.1101/2021.01.20.427408 — developmental biology — Posted on 2021-02-04
3637 The Genetic Basis of phage susceptibility, cross-resistance and host-range in Salmonella
Adler, B. A.; Kazakov, A. E.; Zhong, C.; Liu, H.; Kutter, E.; Lui, L. M.; Nielsen, T. N.; Carion, H.; Deutschbauer, A. M.; Mutalik, V. K.; Arkin, A. P.
10.1101/2020.04.27.058388 — microbiology — Posted on 2021-02-04
3638 Modelling the effects of lymph node swelling on T-cell response
Johnson, S. C.; Frattolin, J.; Edgar, L. T.; Jafarnejad, M.; Moore, J. E.
10.1101/2020.06.19.161232 — immunology — Posted on 2021-02-04
3643 The structural connectome constrains fast brain dynamics
Sorrentino, P.; Seguin, C.; Rucco, R.; Liparoti, M.; Troisi Lopez, E.; Bonavita, S.; Quarantelli, M.; Sorrentino, G.; Jirsa, V.; Zalesky, A.
10.1101/2020.11.25.393017 — neuroscience — Posted on 2021-02-04
3647 Microglia control cerebral blood flow and neurovascular coupling via P2Y12R-mediated actions
Csaszar, E.; Lenart, N.; Cserep, C.; Kornyei, Z.; Fekete, R.; Posfai, B.; Balazsfi, D.; Hangya, B.; Schwarcz, A. D.; Szollosi, D.; Szigeti, K.; Mathe, D.; West, B. L.; Sviatko, K.; Bras, A. R.; Mariani, J. C.; Kliewer, A.; Lenkei, Z.; Hricisak, L.; Benyo, Z.; Baranyi, M.; Sperlagh, B.; Menyhart, A.; Farkas, E.; Denes, A.
10.1101/2021.02.04.429741 — neuroscience — Posted on 2021-02-04
3648 Low doses of the organic insecticide spinosad trigger lysosomal defects, ROS driven lipid dysregulation and neurodegeneration in flies
Martelli, F.; Zuo, Z.; Wang, J.; Wong, C.-O.; Karagas, N. E.; Roessner, U.; Rupasinghe, T.; Venkatachalam, K.; Perry, T.; Batterham, P.; Bellen, H. J.
10.1101/2021.02.03.429672 — neuroscience — Posted on 2021-02-04
3651 Identification of 370 genetic loci for age at first sex and birth linked to externalising behaviour
Mills, M. C.; Tropf, F. C.; Brazel, D. M.; van Zuydam, N.; Vaez, A.; eQTLGen Consortium, ; BIOS Consortium, ; Pers, T. H.; Snieder, H.; Perry, J. R. B.; Ong, K. K.; den Hoed, M.; Barban, N.; Day, F. R.; Human Reproductive Behaviour Consortium,
10.1101/2020.05.06.081273 — genetics — Posted on 2021-02-04
3652 Type-I interferon signatures in SARS-CoV-2 infected Huh7 cells
Chen, X.; Saccon, E.; Appelberg, K. S.; Mikaeloff, F.; Rodriguez, J. E.; Vinhas, B. S.; Frisan, T.; Vegvari, A.; Mirazimi, A.; Neogi, U.; Gupta, S.
10.1101/2021.02.04.429738 — microbiology — Posted on 2021-02-04
3653 Molnupiravir (EIDD-2801) inhibits SARS-CoV-2 replication and enhances the efficacy of favipiravir in a Syrian hamster infection model
Abdelnabi, R.; Foo, C. S.; Kaptein, S. J. F.; Zhang, X.; Langendries, L.; Vangeel, L.; Vergote, V.; Heylen, E.; Leyssen, P.; Dallmeier, K.; coelmont, l.; JOCHMANS, D.; Chatterjee, A. K.; De Jonghe, S.; Weynand, B.; Neyts, J.
10.1101/2020.12.10.419242 — microbiology — Posted on 2021-02-04
3654 The protein modifier SUMO is critical for Arabidopsis shoot meristem maintenance at warmer ambient temperatures
Hammoudi, V.; Beerens, B.; Jonker, M. J.; Helderman, T. A.; Vlachakis, G.; Giesbers, M.; Kwaaitaal, M.; van den Burg, H. A.
10.1101/2021.02.04.429700 — plant biology — Posted on 2021-02-04
3655 Bronchoalveolar lavage affects thorax computed tomography of healthy and SARS-CoV-2 infected rhesus macaques (Macaca mulatta)
Maaskant, A.; Meijer, L.; Bakker, J.; van Geest, L.; Zijlmans, D. G. M.; Langermans, J. A. M.; Verschoor, E. J.; Stammes, M. A.
10.1101/2021.02.04.429761 — biophysics — Posted on 2021-02-04
3656 Age-related susceptibility to insulin resistance is due to a combination of CPT1B decline and lipid overload
Vieira-Lara, M. A.; Dommerholt, M. B.; Zhang, W.; Blankestijn, M.; Wolters, J. C.; Abegaz, F.; van der Veen, Y.; van Dijk, T. H.; van Os, R.; Reijngoud, D.-J.; Jonker, J. W.; Kruit, J. K.; Bakker, B. M.
10.1101/2021.02.04.429529 — biochemistry — Posted on 2021-02-04
3658 Targeted in situ cross-linking mass spectrometry and integrative modeling reveal the architectures of Nsp1, Nsp2, and Nucleocapsid proteins from SARS-CoV-2
Slavin, M.; Zamel, J.; Zohar, K.; Eliyahu, S.; Braitbard, M.; Brielle, E.; Baraz, L.; Stolovich-Rain, M.; Friedman, A.; Wolf, D. G.; Rouvinski, A.; Linial, M.; Schneidman-Duhovny, D.; Kalisman, N.
10.1101/2021.02.04.429751 — biochemistry — Posted on 2021-02-04
3659 Alpha-arrestins Aly1 and Aly2 regulate trafficking of the glycerophosphoinositol transporter Git1 and impact phospholipid homeostasis
Robinson, B. P.; Hawbaker, S. E.; Chiang, A.; Jordahl, E. M.; Anaokar, S.; Nikiforov, A.; Bowman, R. W.; Ziegler, P.; McAtee, C. K.; Patton-Vogt, J.; O'Donnell, A. F.
10.1101/2021.02.04.429748 — cell biology — Posted on 2021-02-04
3661 Speciation of the Mycobacterium tuberculosis complex using mass spectrometry: a proof-of-concept.
Robinne, S.; Saad, J.; Morsli, M.; Harouna, H. Z.; Tazerart, F.; Drancourt, M.; Baron, S. A.
10.1101/2021.02.04.429756 — microbiology — Posted on 2021-02-04
3662 In-depth characterization of HIV-1 reservoirs reveals links to viral rebound during treatment interruption
Cole, B.; Lambrechts, L.; Boyer, Z.; Noppe, Y.; De Scheerder, M.-A.; Eden, J.-S.; Vrancken, B.; Schlub, T.; Frenkel, L. M.; McLaughlin, S.; Palmer, S.; Vandekerckhove, L.
10.1101/2021.02.04.429690 — microbiology — Posted on 2021-02-04
3663 Sensitive visualization of SARS-CoV-2 RNA with CoronaFISH
Rensen, E. I.; Pietropaoli, S.; Weber, C.; Souquere, S.; Isnard, P.; Rabant, M.; Gibier, J.-B.; Simon-Loriere, E.; Rameix-Welti, M.-A.; Pierron, G.; Mueller, F.; Barba-Spaeth, G.; Zimmer, C.
10.1101/2021.02.04.429604 — microbiology — Posted on 2021-02-04
3664 The SARS-CoV-2 transcriptome and the dynamics of the S gene furin cleavage site in primary human airway epithelia
Zou, W.; Xiong, M.; Hao, S.; Zhang-Chen, E. Y.; Baumlin, N.; Kim, M. D.; Salathe, M.; Yan, Z.; Qiu, J.
10.1101/2021.02.03.429670 — microbiology — Posted on 2021-02-04
3666 Analytical Performance of a Standardized Kit for Mass Spectrometry-based Measurements of Human Glycosaminoglycans
Tamburro, D.; Bratulic, S.; Shameh, S. A.; Soni, N. K.; Bacconi, A.; Maccari, F.; Galeotti, F.; Mattsson, K.; Volpi, N.; Nielsen, J.; Gatto, F.
10.1101/2021.02.04.429694 — biochemistry — Posted on 2021-02-04
3670 Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant
Reuschl, A.-K.; Thorne, L.; Zuliani Alvarez, L.; Bouhaddou, M.; Obernier, K.; Hiatt, J.; Soucheray, M.; Turner, J.; Fabius, J.; Nguyen, G. T.; Swaney, D.; Rosales, R.; White, K. M.; Aviles, P.; Kirby, I. T.; Melnyk, J. E.; Shi, Y.; Zhang, Z.; Shokat, K.; Garcia-Sastre, A.; Jolly, C.; Towers, G. J.; Krogan, N. J.
10.1101/2021.01.24.427991 — microbiology — Posted on 2021-02-04
3672 Aquila_stLFR: diploid genome assembly basedstructural variant calling package for stLFRlinked-read
Liu, Y. H.; Grubbs, G. L.; Zhang, L.; Fang, X.; Dill, D. L.; Sidow, A.; Zhou, X.
10.1101/742239 — bioinformatics — Posted on 2021-02-04
3675 Individual variability in structural brain development from late childhood to young adulthood
Mills, K. L.; Siegmund, K. D.; Tamnes, C. K.; Ferschmann, L.; Bos, M. G. N.; Wierenga, L. M.; Luna, B.; Herting, M. L.
10.1101/2021.02.04.429671 — neuroscience — Posted on 2021-02-04
3677 The excitatory/inhibitory balance of synaptic transmission is impaired at higher extracellular Ca2+ concentrations in Scn1a+/- mouse model of Dravet syndrome
Uchino, K.; Kawano, H.; Tanaka, Y.; Adaniya, Y.; Asahara, A.; Deshimaru, M.; Kubota, K.; Watanabe, T.; Katsurabayashi, S.; Iwasaki, K.; Hirose, S.
10.1101/2021.02.04.429687 — neuroscience — Posted on 2021-02-04
3679 Systematic measurement of combination drug landscapes to predict in vivo treatment outcomes for tuberculosis
Larkins-Ford, J.; Greenstein, T.; Van, N.; Degefu, Y. N.; Olson, M. C.; Sokolov, A.; Aldridge, B. B.
10.1101/2021.02.03.429579 — microbiology — Posted on 2021-02-04
3680 Myelin biogenesis is associated with pathological ultrastructure that is resolved by microglia during development
Djannatian, M.; Weikert, U.; Safaiyan, S.; Wrede, C.; Deichsel, C.; Kislinger, G.; Ruhwedel, T.; Campbell, D. S.; van Ham, T. J.; Schmid, B.; Hegermann, J.; Möbius, W.; Schifferer, M.; Simons, M.
10.1101/2021.02.02.429485 — neuroscience — Posted on 2021-02-04
3682 Systematic analysis of brain lactate and pH levels in 65 animal models related to neuropsychiatric conditions
Hagihara, H.; Shoji, H.; Sala, G.; Takamiya, Y.; Tanaka, M.; Hagino, Y.; Kotajima-Murakami, H.; Ikeda, K.; Otabi, H.; Toyoda, A.; Darwish, M.; Nishizono, H.; Takao, K.; Hori, K.; Hoshino, M.; Kim, H.; Kaang, B.-K.; Kohno, T.; Hattori, M.; Matsumoto, K.-i.; Okabe, S.; Ida-Eto, M.; Narita, M.; Fujisawa, H.; Sugimura, Y.; Numakawa, T.; Kunugi, H.; Tabuchi, K.; Katayama, Y.; Nakayama, K. I.; Matsushita, M.; Inazawa, J.; Yamamoto, T.; Nakamura, H.; Goshima, Y.; Hatakama, H.; Asaoka, N.; Kaneko, S.; Tatsukawa, T.; Raveau, M.; Yamakawa, K.; Ihara, M.; Yamanishi, K.; Sapkota, K.; Nakazawa, K.; Graef,
10.1101/2021.02.02.428362 — neuroscience — Posted on 2021-02-04
3683 Protein lactylation induced by neural excitation
Hagihara, H.; Shoji, H.; Otabi, H.; Toyoda, A.; Katoh, K.; Namihira, M.; Miyakawa, T.
10.1101/2021.02.02.428370 — neuroscience — Posted on 2021-02-04
3685 Split-HaloTag Imaging Assay for Sophisticated Microscopy of Protein-Protein Interactions in planta
Minner-Meinen, R.; Weber, J. N.; Albrecht, A.; Matis, R.; Behnecke, M.; Tietge, C.; Frank, S.; Schulze, J.; Buschmann, H.; Walla, P. J.; Mendel, R. R.; Haensch, R.; Kaufholdt, D.
10.1101/2020.06.08.139378 — plant biology — Posted on 2021-02-04
3686 In vivo Evaluation and in silico Prediction of the Toxicity of Drepanoalpha Hard capsules
Gbolo Zoawe, B.; Ngbolua Koto-te-Nyiwa, J.-P.; Tshibangu Sha-Tshibey, D.; Memvanga Bondo, P.; Tshilanda Dinangayi, D.; Matondo, A.; Kilembe Thambwe, J.; Lebwaze Masamba, B.; Nachtergael, A.; Mpiana Tshimankinda, P.; Duez, P.
10.1101/2020.12.03.411124 — pharmacology and toxicology — Posted on 2021-02-04
3690 A protein-based biosensor for detecting calcium by magnetic resonance imaging
Ozbakir, H. F.; Miller, A. D. C.; Fishman, K.; Martins, A. F.; Kippin, T. E.; Mukherjee, A.
10.1101/2021.02.04.429691 — bioengineering — Posted on 2021-02-04
3692 S-acylation targets ORAI1 channels to lipid rafts for efficient Ca2+ signaling by T cell receptors at the immune synapse
Carreras-Sureda, A.; Abrami, L.; JI-Hee, K.; Frieden, M.; Didier, M.; van der Goot, F. G.; Demaurex, N.
10.1101/2021.02.03.429577 — biochemistry — Posted on 2021-02-04
3698 Artificial Intelligence Approaches to Assessing Primary Cilia
Bansal, R.; Engle, S. E.; Kamba, T. K.; Brewer, K.; Lewis, W. R.; Berbari, N. F.
10.1101/2021.02.03.429602 — cell biology — Posted on 2021-02-04
3699 A WDR35-dependent coatomer transports ciliary membrane proteins from the Golgi to the cilia
Quidwai, T.; Hall, E. A.; Keighren, M. A.; Leng, W.; Kiesel, P.; Wells, J. N.; Murphy, L. C.; Marsh, J. A.; Pigino, G.; Mill, P.
10.1101/2020.12.22.423978 — cell biology — Posted on 2021-02-04
3700 A novel adhesive complex at the base of intestinal microvilli
Hartmann, C.; Thuering, E.-M.; Michels, B. E.; Pajonczyk, D.; Leussink, S.; Greune, L.; Brinkmann, F.; Glaesner-Ebnet, M.; Wardelmann, E.; Zobel, T.; Schmidt, M. A.; Gerke, V.; Ebnet, K. T.
10.1101/2021.01.25.428038 — cell biology — Posted on 2021-02-04
3702 Spatial and temporal plasticity of neoantigen-specific T-cell responses bases on characteristics associated to antigen and TCR
Braeunlein, E.; Lupoli, G.; Abalrous, E. T.; de Andrade Kraetzig, N.; Gosmann, D.; Fuechsl, F.; Wietbrock, L.; Lange, S.; Engleitner, T.; Lan, H.; Audehm, S.; Effenberger, M.; Boxberg, M.; Steiger, K.; Chang, Y.; Yu, K.; Atay, C.; Bassermann, F.; Weichert, W.; Busch, D. H.; Rad, R.; Freund, C.; Antes, I.; Krackhardt, A. M.
10.1101/2021.02.02.428777 — immunology — Posted on 2021-02-04
3703 DPSleep: Open-Source Longitudinal Sleep Analysis From Accelerometer Data
Rahimi Eichi, H.; Coombs, G.; Vidal Bustamante, C. M.; Onnela, J.-P.; Baker, J. T.; Buckner, R. L.
10.1101/2021.02.02.429455 — neuroscience — Posted on 2021-02-04
3705 Epigenetic therapy to enhance therapeutic effects of PD-1 inhibition in uveal melanoma
Sah, V. R.; Jespersen, H.; Karlsson, J.; Lindberg, M.; Nilsson, L. M.; Ny, L.; Nilsson, J. A.
10.1101/2021.02.04.429575 — cancer biology — Posted on 2021-02-04
3706 CDK4/6 inhibitors induce replication stress to cause long-term cell cycle withdrawal
Crozier, L.; Foy, R.; Mouery, B. L.; Whitaker, R. H.; Corno, A.; Spanos, C.; Ly, T.; Cook, J. G.; Saurin, A. T.
10.1101/2021.02.03.428245 — cancer biology — Posted on 2021-02-04
3707 Essential role of CFAP53 in sperm flagellum biogenesis
Wu, B. b.; Yu, X. c.; Liu, C.; Wang, L.; Huang, T.; Lu, G.; Chen, Z.-J.; Li, W.; Liu, H. b.
10.1101/2021.02.04.429673 — developmental biology — Posted on 2021-02-04
3708 Tig1 regulates proximo-distal identity during salamander limb regeneration
Oliveira, C. R.; Knapp, D.; Elewa, A.; Gonzalez Malagon, S. G.; Gates, P. B.; Petzold, A.; Arce, H.; Cordoba, R.; Chara, O.; Tanaka, E. M.; Simon, A.; Yun, M.
10.1101/2021.02.03.428234 — developmental biology — Posted on 2021-02-04
3710 Imaging transmembrane dynamics of biomolecules at live cell plasma membranes using quenchers in extracellular environment
Hou, W.; Ma, D.; He, X.; Han, W.; Ma, J.; Wang, H.; Xu, C.; Xie, R.; Fan, Q.-h.; Ye, F.; Hu, S.; Lu, Y.; Li, M.
10.1101/2020.08.30.266148 — biophysics — Posted on 2021-02-04
3711 Revisiting giraffe photo-identification using deep learning and network analysis
Miele, V.; Dussert, G.; Spataro, B.; Chamaille-Jammes, S.; Allaine, D.; Bonenfant, C.
10.1101/2020.03.25.007377 — ecology — Posted on 2021-02-04
3714 Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency
De La Rossa, A.; Laporte, M. H.; Astori, S.; Marissal, T.; Montessuit, S.; Sheshadri, P.; Ramos-Fernández, E.; Mendez, P.; Khani, A.; Quairiaux, C.; Taylor, E.; Rutter, J.; Nunes, J. M.; carleton, a.; Duchen, M.; Sandi, C.; Martinou, J.-C.
10.1101/2020.12.22.423903 — neuroscience — Posted on 2021-02-04
3717 RAD51 nuclear recruitment and inhibition towards innovative strategies against pancreatic cancer
Schipani, F.; Manerba, M.; Marotta, R.; Gennari, A.; Rinaldi, F.; Armirotti, A.; Roberti, M.; Di Stefano, G.; Rocchia, W.; Tirelli, N.; Girotto, S.; Cavalli, A.
10.1101/2021.02.03.429564 — biophysics — Posted on 2021-02-04
3721 Using de novo assembly to identify structural variation of complex immune system gene regions
Zhang, J.-Y.; Roberts, H.; Flores, D. S. C.; Cutler, A. J.; Brown, A. C.; Whalley, J. P.; Mielczarek, O.; Buck, D.; Lockstone, H.; Xella, B.; Oliver, K.; Corton, C.; Betteridge, E.; Bashford-Rogers, R.; Knight, J. C.; Todd, J. A.; Band, G.
10.1101/2021.02.03.429586 — bioinformatics — Posted on 2021-02-04
3722 Automatic Identification and Avoidance of Axon Bundle Activation for Epiretinal Prosthesis
Tandon, P.; Bhaskar, N.; Shah, N.; Madugula, S.; Grosberg, L. E.; Fan, V. H.; Hottowy, P.; Sher, A.; Litke, A. M.; Chichilnisky, E. J.; Mitra, S.
10.1101/2021.02.03.429317 — bioengineering — Posted on 2021-02-03
3723 High-throughput selection of microalgae based on biomass accumulation rates in production environments using PicoShell Particles
van Zee, M.; de Rutte, J.; Rumyan, R.; Williamson, C.; Burnes, T.; Radakovits, R.; Sonico Eugenio, A.; Badih, S.; Lee, D.-H.; Archang, M.; Di Carlo, D.
10.1101/2021.02.03.429271 — bioengineering — Posted on 2021-02-04
3726 Two transcriptionally distinct pathways drive female development in a reptile with both genetic and temperature dependent sex determination
Whiteley, S. L.; Holleley, C. E.; Wagner, S.; Blackburn, J.; Deveson, I. W.; Marshall Graves, J. A.; Georges, A.
10.1101/2021.02.03.429474 — genetics — Posted on 2021-02-04
3733 14-3-3ζ-depletion impairs mammary gland development in the mouse
Poltavets, V.; Esmaeili, Z.; Boyle, S. T.; Ramshaw, H. S.; Lopez, A. F.; Kochetkova, M.; Samuel, M. S.
10.1101/2021.02.03.425513 — cell biology — Posted on 2021-02-03
3734 A modular platform for engineering function ofnatural and synthetic biomolecular condensates
Lasker, K.; Boeynaems, S.; Lam, V.; Stainton, E.; Jacquemyn, M.; Daelemans, D.; Villa, E.; Holehouse, A. S.; Gitler, A.; Shapiro, L.
10.1101/2021.02.03.429226 — cell biology — Posted on 2021-02-03
3740 Plant pathogens convergently evolved to counteract redundant nodes of an NLR immune receptor network
Derevnina, L.; Contreras, M. P.; Adachi, H.; Upson, J.; Vergara Cruces, A.; Xie, R.; Sklenar, J.; Menke, F. L.; Mugford, S. T.; MacLean, D. T.; Ma, W.; Hogenhout, S. A.; Goverse, A.; Maqbool, A.; Wu, C.-h.; Kamoun, S.
10.1101/2021.02.03.429184 — plant biology — Posted on 2021-02-03
3741 Molecular diagnosis and prognosis of cancers of unknown-primary (CUPs): progress from a microRNA-based droplet digital PCR assay
Laprovitera, N.; Riefolo, M.; Porcellini, E.; Durante, G.; Garajova, I.; Vasuri, F.; Aigelsreiter, A.; Dandachi, N.; Benvenuto, G.; Agostinis, F.; Sabbioni, S.; Berindan-Neagoe, I.; Romualdi, C.; Ardizzoni, A.; Trere, D.; Pichler, M.; D'Errico, A.; Ferracin, M.
10.1101/2021.02.03.429509 — pathology — Posted on 2021-02-03
3743 Extending the Near Infrared Emission Range of Indium Phosphide Quantum Dots for Multiplexed In Vivo Imaging
Saeboe, A. M.; Nikiforov, A. Y.; Toufanian, R.; Kays, J. C.; Chern, M.; Han, K.; Casas, J. P.; Piryatinski, A.; Jones, D.; Dennis, A. M.
10.1101/2021.02.03.429632 — bioengineering — Posted on 2021-02-03
3745 Does colour impact attention towards 2D images in geckos?
Katlein, N.; Ray, M.; Wilkinson, A.; Claude, J.; Kiskowski, M.; Wang, B.; Glaberman, S.; Chiari, Y.
10.1101/2021.02.03.429594 — animal behavior and cognition — Posted on 2021-02-03
3746 Using population-specific add-on polymorphisms to improve genotype imputation in underrepresented populations
Xu, Z. M.; Rüeger, S.; Zwyer, M.; Brites, D.; Hiza, H.; Reinhard, M.; Borrell, S.; Isihaka, F.; Temba, H.; Maroa, T.; Naftari, R.; Hella, J.; Sasamalo, M.; Reither, K.; Portevin, D.; Gagneux, S.; Fellay, J.
10.1101/2021.02.03.429542 — genetics — Posted on 2021-02-03
3747 Alien chromatin but not Fhb7 confers Fusarium head blight resistance in wheat breeding
Guo, X.; Shi, Q.; Yuan, J.; Wang, M.; Wang, J.; Wang, C.; Zhang, J.; Fu, S.; Su, H.; Liu, Y.; Wang, L.; Wang, K.; Jing, D.; Zhang, P.; Li, J.; Zhou, Y.; Ye, X.; Han, F.
10.1101/2021.02.03.429547 — genetics — Posted on 2021-02-03
3756 Albendazole reduces endoplasmic reticulum stress induced by Echinococcus multilocularis in mice
Weingartner, M.; Jebbawi, F.; Wang, J.; Stücheli, S.; Gottstein, B.; Beldi, G.; Lundström-Stadelmann, B.; Odermatt, A.
10.1101/2021.02.03.429530 — pathology — Posted on 2021-02-03
3766 Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma
Prummel, K. D.; Crowell, H. L.; Nieuwenhuize, S.; Brombacher, E. C.; Daetwyler, S.; Soneson, C.; Kresoja-Rakic, J.; Ronner, M.; Kocere, A.; Ernst, A.; Labbaf, Z.; Clouthier, D. E.; Firulli, A. B.; Sanchez-Iranzo, H.; Naganathan, S. R.; O'Rourke, R.; Raz, E.; Mercader, N.; Burger, A.; Felley-Bosco, E.; Huisken, J.; Robinson, M. D.; Mosimann, C.
10.1101/2020.11.11.355693 — developmental biology — Posted on 2021-02-03
3767 ADH5-mediated NO Bioactivity Maintains Metabolic Homeostasis in Brown Adipose Tissue
Sebag, S. C.; Zhang, Z.; Qian, Q.; Li, M.; Harata, M.; Li, W.; Zhu, Z.; Zingman, L.; Liu, L.; Lira, V. A.; Potthoff, M. J.; Bartelt, A.; Yang, L.
10.1101/2020.12.27.424489 — molecular biology — Posted on 2021-02-03
3770 Cerebral μ-opioid and CB1-receptor systems have distinct roles in human feeding behavior
Kantonen, T.; Karjalainen, T.; Pekkarinen, L.; Isojärvi, J.; Kalliokoski, K.; Kaasinen, V.; Hirvonen, J.; Nuutila, P.; Nummenmaa, L.
10.1101/2020.12.17.423284 — neuroscience — Posted on 2021-02-03
3772 Predicting modular functions and neural coding of behavior from a synaptic wiring diagram
Vishwanathan, A.; Ramirez, A.; Wu, J.; Sood, A.; Yang, R.; Kemnitz, N.; Ih, D.; Turner, N.; Lee, K.; Tartavull, I.; Silversmith, W. M.; Jordan, C. S.; David, C.; Bland, D.; Goldman, M. S.; Aksay, E.; Seung, H. S.
10.1101/2020.10.28.359620 — neuroscience — Posted on 2021-02-03
3774 Prolonged low-dose dioxin exposure impairs metabolic adaptability to high-fat diet feeding in female but not male mice
Matteo, G.; Hoyeck, M. P.; Blair, H. L.; Zebarth, J.; Rick, K. R.; Williams, A.; Gagne, R.; Buick, J. K.; Yauk, C.; Bruin, J. E.
10.1101/2020.09.12.294587 — pharmacology and toxicology — Posted on 2021-02-03
3776 GranatumX: A community engaging, modularized and flexible software environment for single-cell analysis
Zhu, X.; Yunits, B.; Wolfgruber, T.; Liu, Y.; Huang, Q.; Poirion, O.; Arisdakessian, C.; Zhao, T.; Garmire, D.; Garmire, L.; Stanojevic, S.
10.1101/385591 — bioinformatics — Posted on 2021-02-03
3777 precisionFDA Truth Challenge V2: Calling variants from short- and long-reads in difficult-to-map regions
Olson, N. D.; Wagner, J.; McDaniel, J.; Stephens, S. H.; Westreich, S. T.; Prasanna, A. G.; Johanson, E.; Boja, E.; Maier, E. J.; Serang, O.; Jaspez, D.; Lorenzo-Salazar, J. M.; Munoz-Barrera, A.; Rubio-Rodriguez, L. A.; Flores, C.; Kyriakidis, K.; Malousi, A.; Shafin, K.; Pesout, T.; Jain, M.; Paten, B.; Chang, P.-C.; Kolesnikov, A.; Nattestad, M.; Baid, G.; Goel, S.; Yang, H.; Carroll, A.; Eveleigh, R.; Bourgey, M.; Bourque, G.; Li, G.; MA, C.; Tang, L.; DU, Y.; Zhang, S.; Morata, J.; Tonda, R.; Parra, G.; Trotta, J.-R.; Brueffer, C.; Demirkaya-Budak, S.; Kabakci-Zorlu, D.; Turgut, D.; Kalay
10.1101/2020.11.13.380741 — bioinformatics — Posted on 2021-02-03
3778 The regulatory landscape of Arabidopsis thaliana roots at single-cell resolution
Dorrity, M. W.; Alexandre, C.; Hamm, M.; Vigil, A.-L.; Fields, S.; Queitsch, C.; Cuperus, J.
10.1101/2020.07.17.204792 — genomics — Posted on 2021-02-03
3784 A validation scale to determine the readiness of environmental DNA assays for routine species monitoring
Thalinger, B.; Deiner, K.; Harper, L. R.; Rees, H. C.; Blackman, R. C.; Sint, D.; Traugott, M.; Goldberg, C. S.; Bruce, K.
10.1101/2020.04.27.063990 — molecular biology — Posted on 2021-02-03
3785 Glutamatergic dysfunction precedes neuron loss in cerebral organoids with MAPT mutation.
Bowles, K. R.; Silva, M. C.; Whitney, K.; Bertucci, T.; Garza, J.; Boles, N. C.; Strang, K. H.; Mahali, S.; Marsh, J. A.; Chen, C.; Pugh, D. A.; Liu, Y.; Berlind, J. E.; Lai, J. D.; Goderie, S. K.; Chowdhury, R.; Lotz, S.; Lane, K.; Onanuga, K.; Karch, C.; Ichida, J.; Crary, J. F.; Haggarty, S. J.; Goate, A. M.; Temple, S.
10.1101/2021.02.03.429623 — neuroscience — Posted on 2021-02-03
3789 Discovery of a first-in-class inhibitor of the PRMT5-substrate adaptor interaction
McKinney, D. C.; McMillan, B. J.; Ranaghan, M.; Moroco, J. A.; Brousseau, M.; Mullin-Bernstein, Z.; O'Keefe, M.; McCarren, P.; Mesleh, M. F.; Mulvaney, K. M.; Singh, R.; Bajrami, B.; Skepner, A.; Timm, D. E.; Porter, D.; Kaushik, V.; Sellers, W. R.; Ianari, A.
10.1101/2021.02.03.429644 — cancer biology — Posted on 2021-02-03
3790 RNA polymerase II clusters form in line with liquid phase wetting of chromatin
Pancholi, A.; Klingberg, T.; Zhang, W.; Prizak, R.; Mamontova, I.; Noa, A.; Kobitski, A. Y.; Nienhaus, G. U.; Zaburdaev, V.; Hilbert, L.
10.1101/2021.02.03.429626 — biophysics — Posted on 2021-02-03
3792 Nonsense-mediated decay is highly stable across individuals and tissues.
Teran, N. A.; Nachun, D.; Eulalio, T.; Ferraro, N. M.; Smail, C.; Rivas, M. A.; Montgomery, S. B.
10.1101/2021.02.03.429654 — genomics — Posted on 2021-02-03
3793 Variation in predicted COVID-19 risk among lemurs and lorises
Melin, A. D.; Orkin, J. D.; Janiak, M. C.; Valenzuela, A.; Kuderna, L. F.; Marrone, F.; Ramangason, H.; Horvath, J. E.; Roos, C.; Kitchener, A. C.; Khor, C. C.; Lim, W. K.; Lee, J. G.; Tan, P.; Umapathy, G.; Raveendran, M.; Harris, R. A.; Gut, I.; Gut, M.; Lizano, E.; Nadler, T.; Zinner, D.; Johnson, S. E.; Jarvis, E. D.; Fedrigo, O.; Wu, D.; Zhang, G.; Farh, K. K.-H.; Rogers, J.; Marques-Bonet, T.; Navarro, A.; Juan, D.; Arora, P. S.; Higham, J. P.
10.1101/2021.02.03.429540 — genetics — Posted on 2021-02-03
3794 Global spread and evolutionary history of HCV subtype 3a
Lin, S.-K.; De Maio, N.; Pedergnana, V.; Wu, C.-H.; Theze, J.; Barnes, E.; Ansari, A.
10.1101/2021.02.03.429581 — evolutionary biology — Posted on 2021-02-03
3795 Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development
Mead, T. J.; Martin, D. R.; Wang, L. W.; Cain, S. A.; Gulec, C.; Cahill, E.; Mauch, J.; Reinhardt, D. P.; Lo, C. W.; Baldock, C.; APTE, S.
10.1101/2021.02.03.429587 — developmental biology — Posted on 2021-02-03
3798 MSX2 safeguards syncytiotrophoblast fate of human trophoblast stem cells
Hornbachner, R.; Lackner, A.; Haider, S.; Knöfler, M.; Mechtler, K.; Latos, P. A.
10.1101/2021.02.03.429538 — molecular biology — Posted on 2021-02-03
3799 The promiscuous and highly mobile resistome of a superbug.
Hernandez-Gonzalez, I.; Mateo-Estrada, V.; Castillo-Ramirez, S.
10.1101/2021.02.03.429652 — microbiology — Posted on 2021-02-03
3800 Individuals at risk for developing rheumatoid arthritis harbor differential intestinal bacteriophage communities with distinct metabolic potential
Mangalea, M. R.; Paez-Espino, D.; Kieft, K. A.; Chatterjee, A.; Seifert, J. A.; Feser, M. L.; Demoruelle, M. K.; Chriswell, M. E.; Sakatos, A.; Anantharaman, K.; Deane, K. D.; Kuhn, K. A.; Holers, V. M.; Duerkop, B. A.
10.1101/2021.02.03.429590 — microbiology — Posted on 2021-02-03
3802 Allogeneic CAR-invariant Natural Killer T Cells Exert Potent Antitumor Effects Through Host CD8 T cell Cross-Priming
Simonetta, F.; Lohmeyer, J. K.; Hirai, T.; Maas-Bauer, K.; Alvarez, M.; Wenokur, A. S.; Baker, J.; Aalipour, A.; Ji, X.; Haile, S.; Mackall, C. L.; Negrin, R. S.
10.1101/2021.02.03.428987 — immunology — Posted on 2021-02-03
3803 Fibroblast activation protein regulates natural killer cell migration, extravasation and tumor infiltration
Fitzgerald, A. A.; Marcisak, E. F.; Nasir, A.; Glasgow, E.; Jablonski, S.; Van der Veken, P.; Pearson, G.; Fertig, E. J.; Mace, E. M.; Weiner, L. M.
10.1101/2021.02.03.429622 — immunology — Posted on 2021-02-03
3806 Characterization of the NiRAN domain from RNA-dependent RNA polymerase provides insights into a potential therapeutic target against SARS-CoV-2
Dwivedy, A.; Mariadasse, R.; Ahmad, M.; Chakraborty, S.; Kar, D.; Tiwari, S.; Majumdar, T.; Jeyakanthan, J.; Biswal, B.
10.1101/2021.02.03.429510 — bioinformatics — Posted on 2021-02-03
3807 A high-throughput radioactivity-based assay for screening SARS-CoV-2 nsp10-nsp16 complex
Khalili Yazdi, A.; Li, F.; Devkota, K.; Perveen, S.; Ghiabi, P.; Hajian, T.; Bolotokova, A.; Vedadi, M.
10.1101/2021.02.03.429625 — biochemistry — Posted on 2021-02-03
3810 Summix: A method for detecting and adjusting for population structure in genetic summary data
Arriaga-MacKenzie, I. S.; Matesi, G.; Chen, S.; Ronco, A.; Marker, K. M.; Hall, J. R.; Scherenberg, R.; Khajeh-Sharafabadi, M.; Wu, Y.; Gignoux, C. R.; Null, M.; Hendricks, A. E.
10.1101/2021.02.03.429446 — genetics — Posted on 2021-02-03
3812 Multi-specific DARPin(R) therapeutics demonstrate very high potency against mutated SARS-CoV-2 variants in vitro
Rothenberger, S.; Walser, M.; Malvezzi, F.; Mayor, J.; Ryter, S.; Moreno, H.; Liechti, N.; Halg, S.; Bosshart, A.; Iss, C.; Calabro, V.; Cornelius, A.; Hospodarsch, T.; Neculcea, A.; Looser, T.; Mangold, S.; Reichen, C.; Radom, F.; Dawson, K. M.; Lewis, S.; Steiner, D.; Amstutz, P.; Engler, O.; Stumpp, M. T.
10.1101/2021.02.03.429164 — immunology — Posted on 2021-02-03
3813 Impact of the B.1.1.7 variant on neutralizing monoclonal antibodies recognizing diverse epitopes on SARS-CoV-2 Spike
Graham, C.; Seow, J.; Huettner, I.; Khan, H.; Kouphou, N.; Acors, S.; Winstone, H.; Pickering, S.; Pedro Galao, R.; Jose Lista, M.; Jimenez-Guardeno, J. M.; Laing, A. G.; Wu, Y.; Joseph, M.; Muir, L.; Ng, W. M.; Duyvesteyn, H. M. E.; Zhao, Y.; Bowden, T. A.; Shankar-Hari, M.; Rosa, A.; Cherepanov, P.; McCoy, L. E.; Hayday, A. C.; Neil, S. J. D.; Malim, M. H.; Doores, K. J.
10.1101/2021.02.03.429355 — immunology — Posted on 2021-02-03
3815 Light spectra trigger divergent gene expression in barley cultivars
Monteagudo, A.; Rodriguez del Rio, A.; Contreras-Moreira, B.; Kiss, T.; Mayer, M.; Karsai, I.; Igartua, E.; Casas, A. M.
10.1101/2021.02.03.429565 — plant biology — Posted on 2021-02-03
3819 Establishment of Multi-stage Intravenous Self-administration in Mice
Slosky, L. M.; Pires, A.; Bai, Y.; Clark, N.; Hauser, E. R.; Gross, J. D.; Porkka, F.; Zhou, Y.; Chen, X.; Pogorelov, V. M.; Toth, K.; Wetsel, W. C.; Barak, L. S.; Caron, M. G.
10.1101/2020.11.25.398503 — neuroscience — Posted on 2021-02-03
3822 Autoregulation dependent and independent mechanisms are responsible for the systemic control of nodule formation by the plant N demand
Pervent, M.; Lambert, I.; Tauzin, M.; Kairouani, A.; Nigg, M.; Jardinaud, M.-F.; Severac, D.; Colella, S.; Martin-Magniette, M.-L.; Lepetit, M.
10.1101/2021.02.03.429583 — plant biology — Posted on 2021-02-03
3823 Touch-triggered bZIP translocation regulates elongation and secondary wall biosynthesis
Coomey, J. H.; MacKinnon, K. J.-M.; Handakumbura, P.; McCahill, I. W.; Trabucco, G. M.; Mazzola, J.; Leblanc, N. A.; Kheam, R.; Hernandez-Romero, M.; Barry, K. W.; Liu, L.; Lee, J. E.; Vogel, J. P.; O'Malley, R.; Chambers, J. J.; Hazen, S. P.
10.1101/2021.02.03.429573 — plant biology — Posted on 2021-02-03
3824 Multiple indole glucosinolates and myrosinases defend Arabidopsis against Tetranychus urticae herbivory
Widemann, E.; Bruinsma, K.; Walshe-Roussel, B.; Saha, R. K.; Letwin, D.; Zhurov, V.; Bernards, M. A.; Grbic, M.; Grbic, V.
10.1101/2021.02.03.429630 — plant biology — Posted on 2021-02-03
3826 Structure of plant PSI-plastocyanin complex reveals strong hydrophobic interactions.
Caspy, I.; Fadeeva, M.; Kuhlgert, S.; Borovikova-Sheinker, A.; Klaiman, D.; Masrati, G.; Drepper, F.; Ben-Tal, N.; Hippler, M.; Nelson, N.
10.1101/2021.02.03.429574 — biochemistry — Posted on 2021-02-03
3829 Functional Organization of the Maternal and Paternal Human 4D Nucleome
Lindsly, S. M.; Jia, W.; Chen, H.; Liu, S.; Ronquist, S.; Chen, C.; Wen, X.; Dotson, G.; Ryan, C.; Omenn, G. S.; Li, S. C.; Wicha, M.; Rehemtulla, A.; Muir, L.; Rajapakse, I.
10.1101/2020.03.15.992164 — genomics — Posted on 2021-02-03
3830 Visualizing cellular and tissue ultrastructure using Ten-fold Robust Expansion Microscopy (TREx)
Damstra, H. G. J.; Mohar, B.; Eddison, M.; Akhmanova, A.; Kapitein, L. C.; Tillberg, P. W.
10.1101/2021.02.03.428837 — cell biology — Posted on 2021-02-03
3831 Identification of a Nervous System Gene Expression Signature in Colon Cancer Stem Cells Reveals a Role for Neural Crest Regulators EGR2 and SOX2 in Tumorigenesis
Regan, J. L.; Schumacher, D.; Staudte, S.; Steffen, A.; Lesche, R.; Toedling, J.; Jourdan, T.; Haybaeck, J.; Golob-Schwarzl, N.; Mumberg, D.; Henderson, D.; Gyorffy, B.; Regenbrecht, C. R. A.; Keilholz, U.; Schafer, R.; Lange, M.
10.1101/2021.02.02.428317 — cell biology — Posted on 2021-02-03
3832 Full Brain and Lung Prophylaxis against SARS-CoV-2 by Intranasal Lentiviral Vaccination in a New hACE2 Transgenic Mouse Model or Golden Hamsters
Ku, M.-W.; Authie, P.; Bourgine, M.; Anna, F.; Noirat, A.; Moncoq, F.; Vesin, B.; Nevo, F.; Lopez, J.; Souque, P.; Blanc, C.; Chardenoux, S.; Lafosse, I.; Hardy, D.; Nemirov, K.; Guinet, F.; Langa Vives, F.; Majlessi, L.; Charneau, P.
10.1101/2021.02.03.429211 — microbiology — Posted on 2021-02-03
3834 Assessment of immunogenicity and protective efficacy of ZyCoV-D DNA vaccine candidates in Rhesus macaques against SARS-CoV-2 infection
Yadav, P.; Kumar, S.; Agarwal, K.; Jain, M.; Patil, D.; Maithal, K.; Mathapati, B.; Giri, S.; Mohandas, S.; Shete, A.; Sapkal, G.; Patil, D.; Dey, A.; Chandra, H.; Deshpande, G.; Gupta, N.; Nyayanit, D.; Kaushal, H.; Sahay, R.; Tripathy, A.; Jain, R.; Kumar, A.; Sarkale, P.; Baradkar, S.; Rajanathan, C.; Raju, H. P.; Patel, S.; Shah, N.; Dwivedi, P.; Singh, D.; Abraham, P.
10.1101/2021.02.02.429480 — microbiology — Posted on 2021-02-03
3835 In silico, in vitro and in cellulo models for monitoring SARS-CoV-2 spike/human ACE2 complex, viral entry and cell fusion
Lapaillerie, D.; Chariler, C.; Fernandes, H. S.; Sousa, S.; Lesbats, P.; Weigel, P.; Favereaux, A.; Guyonnnet-Duperat, V.; Parissi, V.
10.1101/2021.02.03.429555 — microbiology — Posted on 2021-02-03
3836 Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection
Pekayvaz, K.; Leunig, A.; Kaiser, R.; Brambs, S.; Joppich, M.; Janjic, A.; Popp, O.; Polewka, V.; Wange, L. E.; Gold, C.; Kirchner, M.; Muenchhoff, M.; Hellmuth, J. C.; Scherer, C.; Eser, T.; Deak, F.; Kuhl, N.; Linder, A.; Saar, K.; Tomas, L.; Schulz, C.; Enard, W.; Kroidl, I.; Geldmacher, C.; von Bergwelt-Baildon, M.; Keppler, O. T.; Zimmer, R.; Mertins, P.; Huebner, N.; Hoelscher, M.; Massberg, S.; Stark, K.; Nicolai, L.
10.1101/2021.02.03.429351 — immunology — Posted on 2021-02-03
3837 Potent in vitro Neutralization of SARS-CoV-2 by Hetero-bivalent Alpaca Nanobodies Targeting the Spike Receptor-Binding Domain
Ma, H.; Zeng, W.; Meng, X.; Huang, X.; Yang, Y.; Zhao, D.; Zhou, P.; Wang, X.; Zhao, C.; Sun, Y.; Wang, P.; Ou, H.; Hu, X.; Xiang, Y.; Jin, T.
10.1101/2021.02.02.429311 — immunology — Posted on 2021-02-03
3838 Adaptive stimulation of macropinocytosis overcomes aspartate limitation in cancer cells under hypoxia
Garcia-Bermudez, J.; Prasad, S.; Baudrier, L.; Badgley, M. A.; Liu, Y.; La, K.; Soula, M.; Williams, R. T.; Yamaguchi, N.; Hwang, R. F.; Taylor, L. J.; De Stanchina, E.; Rostandy, B.; Alwaseem, H.; Molina, H.; Bar-Sagi, D.; Birsoy, K.
10.1101/2021.02.02.429407 — cancer biology — Posted on 2021-02-03
3841 Bacterial expression and purification of functional recombinant SARS-CoV-2 spike receptor binding domain
Prahlad, J.; Struble, L.; Lutz, W. E.; Wallin, S. A.; Khurana, S.; Schnaubelt, A.; Broadhurst, M. J.; Bayles, K.; Borgstahl, G. E. O.
10.1101/2021.02.03.429601 — biochemistry — Posted on 2021-02-03
3842 Discovery of re-purposed drugs that slow SARS-CoV-2 replication in human cells
Pickard, A.; Calverley, B. C.; Chang, J.; Garva, R.; Lu, Y.; Kadler, K. E.
10.1101/2021.01.31.428851 — immunology — Posted on 2021-02-03
3843 LIFE AND WORK OF RESEARCHERS TRAPPED IN THE COVID-19PANDEMIC VICIOUS CYCLE
Ghaffarizadeh, S. A.; Ghaffarizadeh, S. A.; Behbahani, A. H.; Mehdizadeh, M.; Olechowski, A.
10.1101/2021.02.02.429476 — scientific communication and education — Posted on 2021-02-03
3846 Multiscale three-dimensional imaging of intact human organs down to the cellular scale using hierarchical phase-contrast tomography
Walsh, C.; Tafforeau, P.; Wagner, W. L.; Jafree, D. J.; Bellier, A.; Werlein, C.; Kühnel, M. P.; Boller, E.; Walker-Samuel, S.; Robertus, J. L.; Long, D. A.; Jacob, J.; Marussi, S.; Brown, E. E.; Holroyd, N.; Jonigk, D. D.; Ackermann, M.; Lee, P. D.
10.1101/2021.02.03.429481 — physiology — Posted on 2021-02-03
3847 Diffusion of the disordered E-cadherin tail on β-catenin
Wiggers, F.; Wohl, S.; Dubovetskyi, A.; Rosenblum, G.; Zheng, W.; Hofmann, H.
10.1101/2021.02.03.429507 — biophysics — Posted on 2021-02-03
3852 Large portion of essential genes is missed by screening either fly or beetle indicating unexpected diversity of insect gene function
Hakeemi, M. S.; Ansari, S.; Teuscher, M.; Weisskopf, M.; Grossmann, D.; Kessel, T.; Dönitz, J.; Siemanowski, J.; Wan, X.; Schultheis, D.; Frasch, M.; Roth, S.; Schoppmeier, M.; Klingler, M.; Bucher, G.
10.1101/2021.02.03.429118 — genetics — Posted on 2021-02-03
3855 A biomechanical switch regulates the transition towards homeostasis in esophageal epithelium
McGinn, J.; Hallou, A.; Han, S.; Krizic, K.; Ulyanchenko, S.; Iglesias-Bartolome, R.; England, F. J.; Verstreken, C.; Chalut, K. J.; Jensen, K. B.; Simons, B. D.; Alcolea, M. P.
10.1101/2021.02.03.428820 — cell biology — Posted on 2021-02-03
3857 Pathogenic bacteria grown in iron and zinc milieu exhibit magnetotaxis
Ghosh, D.; Kaushik, S.; Thomas, J.; Panwar, V.; Murugesan, P.; Singh, R.; Roy, H. S.; Kumar, R.; Chopra, V.; Gautam, V.
10.1101/2021.02.03.429514 — microbiology — Posted on 2021-02-03
3858 In vivo antigen expression regulates CD4 T cell differentiation and vaccine efficacy against Mycobacterium tuberculosis infection
Strand Clemmensen, H.; Dube, J.-Y.; McIntosh, F.; Rosenkrands, I.; Jungersen, G.; Aagaard, C.; Andersen, P.; Behr, M. A.; Mortensen, R.
10.1101/2021.02.02.429488 — immunology — Posted on 2021-02-03
3860 MTHFD2 is a Metabolic Checkpoint Controlling Effector and Regulatory T Cell Fate and Function
Sugiura, A.; Andrejeva, G.; Voss, K.; Heintzman, D. R.; Beier, K. L.; Wolf, M. M.; Greenwood, D. L.; Ye, X.; Shahi, S. K.; Freedman, S. N.; Cameron, A. M.; Foerch, P.; Bourne, T.; Xu, X.; Garcia-Canaveras, J. C.; Mangalam, A. K.; Rabinowitz, J.; Rathmell, J.
10.1101/2021.02.03.428939 — immunology — Posted on 2021-02-03
3861 Down Regulation Of IL-1β Secretion By TGF-β1 In Macrophages Infected With Dengue Virus
Ramirez-Aguero, B.; Serrato-Salas, J.; Montiel Hernandez, J. L.; Gonzalez-Christen, J.
10.1101/2021.02.03.429556 — immunology — Posted on 2021-02-03
3862 Mechanoreceptor synapses in the brainstem shape the central representation of touch
Lehnert, B. P.; Santiago, C.; Huey, E. L.; Emanuel, A. J.; Renauld, S.; Africawala, N.; Alkislar, I.; Zheng, Y.; Bai, L.; Koutsioumpa, C.; Hong, J. T.; Magee, A. R.; Harvey, C. D.; Ginty, D. D.
10.1101/2021.02.02.429463 — neuroscience — Posted on 2021-02-03
3864 Central inhibition of P2Y12R differentially regulates survival and neuronal loss in MPTP-induced Parkinsonism in mice
Iring, A.; Toth, A.; Baranyi, M.; Otrokocsi, L.; Modis, L. V.; Goloncser, F.; Varga, B.; Hortobagyi, T.; Bereczki, D.; Denes, A.; Sperlagh, B.
10.1101/2021.02.03.256941 — neuroscience — Posted on 2021-02-03
3865 Brain2Pix: Fully convolutional naturalistic video reconstruction from brain activity
Le, L.; Ambrogioni, L.; Seeliger, K.; Güclütürk, Y.; van Gerven, M.; Güclü, U.
10.1101/2021.02.02.429430 — neuroscience — Posted on 2021-02-03
3867 Hoplonemertean larvae are planktonic predators that capture and devour active animal prey
von Dassow, G.; Mendes, C. B.; Robbins, K.; Andrade, S. C. S.; Maslakova, S. A.
10.1101/2021.02.02.429399 — zoology — Posted on 2021-02-03
3868 High Throughput Fitness Profiling Reveals Loss Of GacS-GacA Regulation Improves Indigoidine Production In Pseudomonas putida
Eng, T. T.; Banerjee, D.; Lau, A. K.; Bowden, E.; Herbert, R. A.; Trinh, J.; Prahl, J.-P.; Deutschbauer, A.; Tanjore, D.; Mukhopadhyay, A.
10.1101/2021.02.02.429437 — systems biology — Posted on 2021-02-03
3869 The effect of mentee and mentor gender on scientific productivity of applicants for NIH training fellowships
Yu, H.; Willis, K. A.; Litovitz, A.; Harriman, R. M.; Davis, M. T.; Meyer, P.; Busse, B.; Meseroll, R. A.; Wijayatilake, H. D.; Perkins, M. J.; Anderson, J. M.; Santangelo, G. M.
10.1101/2021.02.02.429450 — scientific communication and education — Posted on 2021-02-03
3873 Redefining tumor classification and clinical stratification through a colorectal cancer single-cell atlas
Khaliq, A. M.; kurt, z.; Grunvald, M. W.; Erdogan, C.; Turgut, S. S.; Rand, T.; Khare, S.; Borgia, J. A.; Hayden, D. M.; Pappas, S. G.; Govekar, H. R.; Bhama, A. R.; Singh, A.; Jacobson, R. A.; Kam, A. E.; Zloza, A.; Reiser, J.; Catenacci, D. V.; Turaga, K.; Radovich, M.; Thyparambil, S.; Levy, M. A.; Subramanian, J.; Kuzel, T. M.; Sadanandam, A.; Hussain, A.; El-Rayes, B.; Salahudeen, A.; Masood, A.
10.1101/2021.02.02.429256 — cancer biology — Posted on 2021-02-03
3874 Voltage-Gated Potassium Channel Kv1.3 as a Therapeutic Target for Pancreatic Ductal Adenocarcinoma
Li, W.; Wilson, G.; Bachmann, M.; Wang, J.; Mattarei, A.; Paradisi, C.; Edwards, M.; Szabo, I.; Gulbins, E.; Ahmad, S.; Patel, S.
10.1101/2021.02.03.429505 — cancer biology — Posted on 2021-02-03
3875 Three-dimensional interactions between integrated HPV genomes and cellular chromatin dysregulate host gene expression in early cervical carcinogenesis
Groves, I. J.; Drane, E. L.; Michalski, M.; Monahan, J. M.; Scarpini, C. G.; Smith, S. P.; Bussotti, G.; Varnai, C.; Schoenfelder, S.; Fraser, P.; Enright, A. J.; Coleman, N.
10.1101/2021.02.03.429496 — cancer biology — Posted on 2021-02-03
3877 Sorghum pan-genome explores the functional utility to accelerate the genetic gain
Ruperao, P.; Thirunavukkarasu, N.; Gandham, P.; Selvanayagam, S.; M, G.; Nebie, B.; Manyasa, E.; Gupta, R.; Gandhi, H.; Das, R. R.; Edwards, D.; Deshpande, S.; Rathore, A.
10.1101/2021.02.02.429137 — bioinformatics — Posted on 2021-02-03
3881 Lateral Undulation Aids Biological and Robotic Earthworm Anchoring and Locomotion
Ozkan-Aydin, Y.; Liu, B.; Carruthers Ferrero, A.; Seidel, M.; Hammond, F. L.; Goldman, D. I.
10.1101/2021.02.02.429151 — animal behavior and cognition — Posted on 2021-02-03
3884 Characterization of Poldip2 knockout mice: avoiding incorrect gene targeting
Lassegue, B.; Kumar, S.; Mandavilli, R.; Wang, K.; Tzai, M.; Kang, D.-W.; Hernandes, M. S.; San Martin, A.; Jo, H.; Taylor, W. R.; Griendling, K. K.
10.1101/2021.02.02.429447 — genetics — Posted on 2021-02-03
3889 Transmission of pre-XDR and XDR-TB in the Mumbai Metropolitan Region, India
Dreyer, V.; Mandal, A.; Dev, P.; Merker, M.; Barilar, I.; Utpatel, C.; Nilgiriwala, K.; Rodrigues, C.; Crook, D. W.; CRyPTIC Consortium, ; Mistry, N. S.; Niemann, S.
10.1101/2021.02.02.429364 — molecular biology — Posted on 2021-02-03
3890 Year-round dynamics of amplicon sequence variant communities differ among eukaryotes, Mimiviridae, and prokaryotes in a coastal ecosystem
Prodinger, F.; Endo, H.; Takano, Y.; Li, Y.; Tominaga, K.; Isozaki, T.; Blanc-Mathieu, R.; Gotoh, Y.; Tetsuya, H.; Taniguchi, E.; Nagasaki, K.; Yoshida, T.; Ogata, H.
10.1101/2021.02.02.429489 — microbiology — Posted on 2021-02-03
3891 Defining a Connectome-Based Predictive Model of Attentional Control in Aging
Fountain-Zaragoza, S.; Manglani, H. R.; Rosenberg, M. D.; Andridge, R.; Prakash, R. S.
10.1101/2021.02.02.429232 — neuroscience — Posted on 2021-02-03
3893 Marker-free imaging of α-Synuclein aggregates in a rat model of Parkinson' disease using Raman microspectroscopy
Sevgi, F.; Brauchle, E. M.; Carvajal-Berrio, D. A.; Schenke-Layland, K.; Casadei, N.; Salker, M.; Riess, O.; Singh, Y.
10.1101/2021.02.02.429468 — neuroscience — Posted on 2021-02-03
3894 Extracellular membrane tubules involved in suberin deposition in plant cell walls
De Bellis, D.; Kalmbach, L.; Marhavy, P.; Daraspe, J.; Geldner, N.; Barberon, M.
10.1101/2021.02.02.429332 — plant biology — Posted on 2021-02-03
3895 Adaptive stimulation of macropinocytosis overcomes aspartate limitation in cancer cells under hypoxia
Birsoy, K.; Bar-Sagi, D.; Garcia-Bermudez, J.; Prasad, S.; Baudrier, L.; Badgley, M. A.; Liu, Y.; La, K.; Soula, M.; Williams, R. T.; Yamaguchi, N.; Hwang, R. F.; Taylor, L. J.; De Stanchina, E.; Rostandy, B.; Alwaseem, H.; Molina, H.
10.1101/2021.02.02.429407 — cancer biology — Posted on 2021-02-03
3896 MicroPIPE: An end-to-end solution for high-quality complete bacterial genome construction
Murigneux, V.; Roberts, L.; Forde, B. M.; Phan, M.-D.; Nguyen, T. K. N.; Irwin, A. D.; Harris, P. N. A.; Paterson, D. L.; Schembri, M. A.; Whiley, D. M.; Beatson, S. A.
10.1101/2021.02.02.429319 — bioinformatics — Posted on 2021-02-03
3902 INCORPORATING A DYNAMIC GENE-BASED PROCESS MODULE INTO A CROP SIMULATION MODEL
Oliveira, F. A. A.; Jones, J. W.; Pavan, W.; Bhakta, M.; Vallejos, C. E.; Correll, M. J.; Boote, K. J.; Fernandes, J. M. C.; Hölbig, C. A.; Hoogenboom, G.
10.1101/2021.02.02.429409 — genomics — Posted on 2021-02-03
3903 SYSTEM ANALYSIS OF THE SEQUENCING QUALITY OF HUMAN WHOLE EXOME SAMPLES ON BGI NGS PLATFORM
Belova, V.; Pavlova, A.; Afasizhev, R.; Moskalenko, V.; Korzhanova, M.; Cheranev, V.; Krivoy, A.; Nikashin, B.; Bulusheva, I.; Rebrikov, D.; Korostin, D.
10.1101/2021.02.02.429394 — genomics — Posted on 2021-02-03
3906 Climate, latitude, and land cover predict flying insect biomass across a German malaise trap network
Welti, E. A. R.; Zajicek, P.; Ayasse, M.; Bornholdt, T.; Buse, J.; Dziock, F.; Engelmann, R. A.; Englmeier, J.; Fellendorf, M.; Forschler, M. I.; Frenzel, M.; Fricke, U.; Ganuza, C.; Hippke, M.; Hoenselaar, G.; Kaus-Thiel, A.; Mandery, K.; Marten, A.; Monaghan, M. T.; Morkel, C.; Muller, J.; Puffpaff, S.; Redlich, S.; Richter, R.; Rojas Botero, S.; Scharnweber, T.; Scheiffarth, G.; Schmidt Yanez, P.; Schumann, R.; Seibold, S.; Steffan-Dewenter, I.; Stoll, S.; Tobisch, C.; Twietmeyer, S.; Uhler, J.; Vogt, J.; Weis, D.; Weisser, W. W.; Wilmking, M.; Haase, P.
10.1101/2021.02.02.429363 — ecology — Posted on 2021-02-03
3908 Unravelling the Physiological Correlates of Mental Workload Variations in Tracking and Collision Prediction Tasks: Implications for Air Traffic Controllers
John, A. R.; Singh, A. K.; Do, T.-T. N.; Eidels, A.; Nalivaiko, E.; Gavgani, A. M.; Brown, S.; Bennett, M.; Lal, S.; Simpson, A. M.; Gustin, S. M.; Double, K.; Walker, F. R.; Kleitman, S.; Morley, J.; Lin, C.-T.
10.1101/2021.02.02.428702 — neuroscience — Posted on 2021-02-03
3910 Alpha oscillations shape sensory representation and perceptual accuracy
Zhou, Y. J.; Iemi, L.; Schoffelen, J.-M.; de Lange, F. P.; Haegens, S.
10.1101/2021.02.02.429418 — neuroscience — Posted on 2021-02-03
3911 Artificial light at night leads to circadian disruption in a songbird: integrated evidence from behavioural, genomic and metabolomic data
Dominoni, D. M.; de Jong, M.; van Oers, K.; O'Shaughnessy, P. J.; Blackburn, G.; Atema, E.; Mateman, C. A.; D'Amelio, P. B.; Trost, L.; Bellingham, M.; Clark, J.; Visser, M.; Helm, B.
10.1101/2020.12.18.423473 — zoology — Posted on 2021-02-03
3912 An updated staging system for cephalochordate development: one table suits them all
Carvalho, J. E.; Lahaye, F.; Yong, L. W.; Croce, J. C.; Escriva, H.; Yu, J.-K.; Schubert, M.
10.1101/2020.05.26.112193 — developmental biology — Posted on 2021-02-03
3913 Sleeping at the Switch
Bouchard, M.; Lina, J.-M.; Gaudreault, P.-O.; Lafreniere, A.; Dube, J.; Gosselin, N.; Carrier, J.
10.1101/2021.02.02.429396 — neuroscience — Posted on 2021-02-03
3914 Encoding of motion by spatial and temporal frequency in the human middle temporal cortex measured by 7T fMRI
Gaglianese, A.; Fracasso, A.; Fernandes, F. G.; Harvey, B. M.; Dumoulin, S. O.; Petridou, N.
10.1101/2021.02.01.429141 — neuroscience — Posted on 2021-02-03
3916 cGMP signaling: probing antagonistic cyclic nucleotide platelet signals by modeling and experiment
Dandekar, T.; Friebe, A.; Feil, R.; Dittrich, M.; Breitenbach, T.; Englert, N.; Osmanoglu, O.; rukoyatkina, n.; Wangorsch, G.; Butt, E.; Gambaryan, S.
10.1101/2021.02.01.429103 — systems biology — Posted on 2021-02-03
3920 Extracellular matrix stiffness regulates degradation of the Hippo kinase MST2 via SCFβTrCP
Fiore, A. P. Z. P.; da Silva, A. M. R.; Ribeiro, H. V.; Manucci, A. C.; Ribeiro, P. d. F.; Silva Botelho, M. C.; Oliveira, P. S. L.; Pagano, M.; Bruni-Cardoso, A.
10.1101/2021.01.31.429078 — cell biology — Posted on 2021-02-03
3921 Factors affecting bacterial community dynamics and volatile metabolite profiles of Thai traditional salt fermented fish
Det-udom, R.; Settachaimongkon, S.; Chancharoonpong, C.; Suphamityotin, P.; Suriya, A.; Prakitchaiwattana, C.
10.1101/2021.02.02.429487 — microbiology — Posted on 2021-02-03
3924 Systematic analysis of brain lactate and pH levels in 65 animal models related to neuropsychiatric conditions
Hagihara, H.; Shoji, H.; Sala, G.; Takamiya, Y.; Tanaka, M.; Hagino, Y.; Kotajima-Murakami, H.; Ikeda, K.; Otabi, H.; Toyoda, A.; Darwish, M.; Nishizono, H.; Takao, K.; Hori, K.; Hoshino, M.; Kim, H.; Kaang, B.-K.; Kohno, T.; Hattori, M.; Matsumoto, K.-i.; Okabe, S.; Ida-Eto, M.; Narita, M.; Fujisawa, H.; Sugimura, Y.; Numakawa, T.; Kunugi, H.; Tabuchi, K.; Katayama, Y.; Nakayama, K. I.; Matsushita, M.; Inazawa, J.; Yamamoto, T.; Nakamura, H.; Goshima, Y.; Hatakama, H.; Asaoka, N.; Kaneko, S.; Tatsukawa, T.; Raveau, M.; Yamakawa, K.; Ihara, M.; Yamanishi, K.; Sapkota, K.; Nakazawa, K.; Graef,
10.1101/2021.02.02.428362 — neuroscience — Posted on 2021-02-03
3928 Identification of novel inner membrane complex and apical annuli proteins of the malaria parasite Plasmodium falciparum
Wichers, J. S.; Wunderlich, J.; Heincke, D.; Pazicky, S.; Strauss, J.; Schmitt, M.; Kimmel, J.; Wilcke, L.; Scharf, S.; von Thien, H.; Burda, P.-C.; Spielmann, T.; Loew, C.; Filarsky, M.; Bachmann, A.; Gilberger, T. W.
10.1101/2021.02.03.428885 — cell biology — Posted on 2021-02-03
3930 ChIPuana: from raw data to epigenomic dynamics
Daunesse, M.; Legendre, R.; Varet, H.; Pain, A.; Chica, C.
10.1101/2021.02.02.429342 — bioinformatics — Posted on 2021-02-03
3932 Replacement of microglia by brain-engrafted macrophages provide long term protection against brain irradiation and concussive injury
Feng, X.; Frias, E.; Paladini, M.-S.; Chen, D.; Boosalis, Z.; Becker, M.; Gupta, S.; Liu, S.; Gupta, N.; Rosi, S.
10.1101/794354 — neuroscience — Posted on 2021-02-03
3934 Investigation of USP30 inhibition to enhance Parkin-mediated mitophagy: tools and approaches
Ketteler, R.; Tsefou, E.; Walker, A. S.; Clark, E. H.; Hicks, A. R.; Luft, C.; Takeda, K.; Watanabe, T.; Ramazio, B.; Staddon, J. M.; Briston, T.
10.1101/2021.02.02.429344 — neuroscience — Posted on 2021-02-02
3935 A feed-forward Ca2+-dependent mechanism boosting glycolysis and OXPHOS by activating Aralar-malate-aspartate shuttle, upon neuronal stimulation
Perez-Liebana, I.; Juaristi, I.; Gonzalez-Sanchez, P.; Gonzalez-Moreno, L.; Rial, E.; Podunavac, M.; Zakarian, A.; Molgo, J.; Pardo, B.; Satrustegui, J.; del Arco, A.
10.1101/2021.02.02.429391 — neuroscience — Posted on 2021-02-03
3936 Multicellular immune hubs and their organization in MMRd and MMRp colorectal cancer
Pelka, K.; Hofree, M.; Chen, J.; Sarkizova, S.; Pirl, J. D.; Jorgji, V.; Bejnood, A.; Dionne, D.; Ge, W. H.; Xu, K. H.; Chao, S. X.; Zollinger, D. R.; Lieb, D. J.; Reeves, J. W.; Fuhrman, C. A.; Hoang, M. L.; Delorey, T.; Nguyen, L. T.; Waldman, J.; Klapholz, M.; Wakiro, I.; Cohen, O.; Smillie, C. S.; Cuoco, M. S.; Wu, J.; Su, M.-j.; Yeung, J.; Vijaykumar, B.; Magnuson, A. M.; Asinovski, N.; Moll, T.; Goder-Reiser, M. N.; Applebaum, A. S.; Brais, L. K.; DelloStritto, L. K.; Denning, S. L.; Phillips, S. T.; Hill, E. K.; Meehan, J. K.; Frederick, D. T.; Sharova, T.; Kanodia, A.; Todres, E. Z.; J
10.1101/2021.01.30.426796 — cancer biology — Posted on 2021-02-02
3939 Neural Fragility as an EEG Marker of the Seizure Onset Zone
Li, A.; Huynh, C.; Fitzgerald, Z.; Cajigas, I.; Brusko, D.; Claudio, A.; Jagid, J.; Kanner, A.; Hopp, J.; Chen, S.; Haagensen, J.; Johnson, E.; Crone, N.; Anderson, W.; Inati, S.; Zaghloul, K.; Bulacio, J.; Martinez, J.; Sarma, S.
10.1101/862797 — neuroscience — Posted on 2021-02-02
3940 Modeling autism-associated SHANK3 deficiency using human cortico-striatal organoids generated from single neural rosettes
Wang, Y.; Chiola, S.; Yang, G.; Russell, C.; Armstrong, C. J.; Wu, Y.; Spampanato, J.; Tarboton, P.; Chang, A. N.; Harmin, D. A.; Vezzoli, E.; Besusso, D.; Cui, J.; Cattaneo, E.; Kubanek, J.; Shcheglovitov, A.
10.1101/2021.01.25.428022 — neuroscience — Posted on 2021-02-02
3942 Transcriptional Profiling Reveals the Transcription Factor Networks Regulating the Survival of Striatal Neurons
Yang, L.; Su, Z.; Wang, Z.; Li, Z.; Shang, Z.; Du, H.; Liu, G.; Qi, D.; Yang, Z.; Xu, Z.; Zhang, Z.
10.1101/2020.05.20.105585 — neuroscience — Posted on 2021-02-02
3944 DAZL regulates mRNA deadenylation independently of translation in germ cells
Smith, R. W.; Gorgoni, B.; Johnston, Z. C.; Richardson, W. A.; Grieve, K. M.; Anderson, R. C.; Gray, N. K.
10.1101/2021.02.02.429436 — molecular biology — Posted on 2021-02-02
3947 Cubam receptor-mediated endocytosis in hindgut-derived pseudoplacenta of a viviparous teleost Xenotoca eiseni
Iida, A.; Sano, K.; Inokuchi, M.; Suzuki, T.; Kuriki, M.; Sogabe, M.; Susaki, D.; Tonosaki, K.; Kinoshita, T.; Hondo, E.
10.1101/2021.02.01.429082 — zoology — Posted on 2021-02-02
3949 Characterization of novel regulatory modules controlling leaf angle in maize
Wang, X.; Wang, X.; Sun, S.; Tu, X.; Lin, K.; Qin, L.; Wang, X.; Li, G.; Zhong, S.; Li, P.
10.1101/2021.02.02.429433 — plant biology — Posted on 2021-02-02
3951 The Arabidopsis AAC Proteins CIL and CIA2 Are Sub-functionalized Paralogs involved in Chloroplast Development
Li, M.; Ruwe, H.; Melzer, M.; Junker, A.; Hensel, G.; Tschiersch, H.; Schwenkert, S.; Chamas, S.; Schmitz-Linneweber, C.; Boerner, T.; Stein, N.
10.1101/2021.02.02.429330 — plant biology — Posted on 2021-02-02
3952 Teosinte introgression modulates phosphatidylcholine levels and induces early maize flowering time
Rodriguez-Zapata, F.; Barnes, A. C.; Blocher-Juarez, K. A.; Gates, D. J.; Kur, A.; Wang, L.; Jensen, S. E.; Estevez-Palmas, J. M. M.; Janzen, G. M.; Crow, T. M.; Aguilar-Rangel, R.; Demesa-Arevalo, E.; Skopelitis, T.; Perez-Limon, S.; Stutts, W. L.; Thomson, P. M.; Chiu, Y.-C.; Jackson, D.; Fiehn, O.; Runcie, D.; Buckler, E. S.; Ross-Ibarra, J.; Hufford, M.; Sawers, R. J.; Rellan-Alvarez, R.
10.1101/2021.01.25.426574 — plant biology — Posted on 2021-02-02
3955 Akr1d1-/- mice have a sexually dimorphic metabolic phenotype with reduced fat mass, increased insulin sensitivity and hypertriglyceridemia in males
Gathercole, L. L.; Nikolaou, N.; Arvaniti, A.; Harris, S. E.; Poolman, T. M.; Hazlehurst, J. M.; Kratschmar, D. V.; Todorcevic, M.; Moolla, A.; Dempster, N.; Pink, R. C.; Saikali, M. F.; Bentley, L.; Penning, T. M.; Ohlsson, C.; Cummins, C. L.; Poutanen, M.; Odermatt, A.; Cox, R. D.; Tomlinson, J. W.
10.1101/2021.02.02.429227 — physiology — Posted on 2021-02-02
3960 A metabolic CRISPR-Cas9 screen in Chinese hamster ovary cells identifies glutamine-sensitive genes
Karottki, K. J. l. C.; Hefzi, H.; Li, S.; Pedersen, L. E.; Spahn, P.; Joshi, C.; Ruckerbauer, D.; Bort, J. H.; Thomas, A.; Lee, J. S.; Borth, N.; Lee, G. M.; Kildegaard, H. F.; Lewis, N. E.
10.1101/2020.05.07.081604 — bioengineering — Posted on 2021-02-02
3961 Is energetics or competition a stronger driver of male smallmouth bass seasonal reproductive timing?
Laroche, R. A. S.; Weinersmith, K. L.; Angeloni, L.; Baylis, J. R.; Newman, S. P.; Egan, S. P.; Wiegmann, D. D.
10.1101/2021.01.30.428956 — animal behavior and cognition — Posted on 2021-02-02
3963 Chromosome-level genome assemblies of the malaria vectors Anopheles coluzzii and Anopheles arabiensis
Zamyatin, A.; Avdeyev, P.; Liang, J.; Sharma, A.; Chen, C.; Lukyanchikova, V.; Alexeev, N.; Tu, Z.; Alekseyev, M. A.; Sharakhov, I. V.
10.1101/2020.09.29.318477 — genomics — Posted on 2021-02-02
3964 Myoglobin primary structure reveals multiple convergent transitions to semi-aquatic life in the world smallest mammalian divers
He, K.; Eastman, T. G.; Czolacz, H.; Li, S.; Shinohara, A.; Kawada, S.-i.; Springer, M.; Berenbrink, M.; Campbell, K. L.
10.1101/2021.01.14.426706 — evolutionary biology — Posted on 2021-02-02
3966 EGR4-dependent decrease of UTF1 is associated with failure to reserve spermatogonial stem cells in infertile men
Di Persio, S.; Tekath, T.; Siebert-Kuss, L. M.; Cremers, J.-F.; Wistuba, J.; Li, X.; Meyer zu Hoerste, G.; Drexler, H. C.; Wyrwoll, M. J.; Tuettelmann, F.; Dugas, M.; Kliesch, S.; Schlatt, S.; Laurentino, S.; Neuhaus, N.
10.1101/2021.02.02.429371 — molecular biology — Posted on 2021-02-02
3967 Spray-induced gene silencing for disease control is dependent on the efficiency of pathogen RNA uptake
Qiao, L.; Lan, C.; Capriotti, L.; Ah-Fong, A.; Nino Sanchez, J.; Hamby, R.; Heller, J.; Zhao, H.; Glass, N. L.; Judelson, H. S.; Mezzetti, B.; Niu, D.; Jin, H.
10.1101/2021.02.01.429265 — microbiology — Posted on 2021-02-02
3969 Social Reactivation of Fear Engrams Enhances Recall and Reinstatement
Finkelstein, A. B.; Leblanc, H.; Cole, R.; Gallerani, T.; Vieira, A.; Zaki, Y.; Ramirez, S.
10.1101/2021.01.07.425728 — neuroscience — Posted on 2021-02-02
3972 Sensory experience selectively reorganizes the late component of evoked responses
Bermudez Contreras, E.; Gomez Palacio-Schjetnan, A.; Luczak, A.; Mohajerani, M. H.
10.1101/2020.09.30.321547 — neuroscience — Posted on 2021-02-02
3974 Mapping the contents of consciousness during musical imagery
Regev, M.; Halpern, A. R.; Owen, A. M.; Patel, A. D.; Zatorre, R. J.
10.1101/2020.11.20.391375 — neuroscience — Posted on 2021-02-02
3975 PDE9 Inhibition Activates PPARa to Stimulate Mitochondrial Fat Metabolism and Reduce Cardiometabolic Syndrome
Mishra, S.; Hahn, V.; Sadagopan, N.; Dunkerly-Eyring, B.; Rodriguez, S.; Sarver, D. C.; Ceddia, R. P.; Murphy, S.; Knutsdottir, H.; Jani, V.; Ashok, D.; Oeing, C. U.; O'Rourke, B.; Sharma, K.; Gangoiti, J.; Sears, D. D.; Wong, G. W.; Collins, S.; Kass, D. A.
10.1101/2021.02.02.429442 — physiology — Posted on 2021-02-02
3976 Characterisation of tumour immune microenvironment remodelling following oncogene inhibition in preclinical studies using an optimised imaging mass cytometry workflow
van Maldegem, F.; Valand, K.; Cole, M.; Patel, H.; Angelova, M.; Rana, S.; Colliver, E.; Enfield, K.; Bah, N.; Tsang, V.; Mugarza, E.; Moore, C.; Hobson, P.; Levi, D.; Molina, M.; Swanton, C.; Downward, J.
10.1101/2021.02.02.429358 — cancer biology — Posted on 2021-02-02
3977 H3K27me3 mediated KRT14 upregulation promotes TNBC peritoneal metastasis
Verma, A.; Singh, A.; Nengroo, M. A.; Saini, K.; Sinha, A.; Singh, A. K.; Datta, D.
10.1101/2021.02.02.429349 — cancer biology — Posted on 2021-02-02
3978 Analysis of gastric cancer transcriptome allows the identification of histotype specific molecular signatures with prognostic potential
Carino, A.; Graziosi, L.; Marchiano, S.; Biagioli, M.; Marino, E.; Sepe, V.; Zampella, A.; Distrutti, E.; Donini, A.; Fiorucci, S.
10.1101/2021.02.02.429357 — cancer biology — Posted on 2021-02-02
3979 Refinement of α-synuclein ensembles against SAXS data: Comparison of force fields and methods
Ahmed, M. C.; Skaanning, L. K.; Jussupow, A.; Newcombe, E. A.; Kragelund, B. B.; Camilloni, C.; Langkilde, A. E.; Lindorff-Larsen, K.
10.1101/2021.01.15.426794 — biophysics — Posted on 2021-02-02
3980 Genotyping common, large structural variations in 5,202 genomes using pangenomes, the Giraffe mapper, and the vg toolkit
Siren, J.; Monlong, J.; Chang, X.; Novak, A. M.; Eizenga, J. M.; Markello, C.; Sibbesen, J. A.; Hickey, G.; Chang, P.-C.; Carroll, A.; Gupta, N.; Gabriel, S.; Blackwell, T. W.; Ratan, A.; Taylor, K. D.; Rich, S. S.; Rotter, J. I.; Haussler, D.; Garrison, E.; Paten, B.
10.1101/2020.12.04.412486 — bioinformatics — Posted on 2021-02-02
3981 4DNvestigator: Time Series Genomic Data Analysis Toolbox
Lindsly, S. M.; Chen, C.; Lu, S.; Ronquist, S.; Dilworth, S.; Perlman, M.; Rajapakse, I.
10.1101/2020.01.08.898387 — bioinformatics — Posted on 2021-02-02
3984 PASV: Automatic protein partitioning and validation using conserved residues
Moore, R. M.; Harrison, A. O.; Nasko, D. J.; Chopyk, J.; Cebeci, M.; Ferrell, B. D.; Polson, S. W.; Wommack, K. E.
10.1101/2021.01.20.427478 — bioinformatics — Posted on 2021-02-02
3987 Long noncoding RNA VENTHEART is required for cardiomyocyte specification and function
Dashi, A.; Lek Wen, T. W.; Anene, G.; Pan, B.; Autio, M. I.; Tiang, Z.; Hartman, R.; Stenzig, J.; Wei, H.; Chen, G.; Ackers-Johnson, M.; Lim, B.; Walentinsson, A.; Iyer, V.; Jonsson, M.; Foo, R.
10.1101/2021.02.01.429136 — cell biology — Posted on 2021-02-02
3989 Balanced Input from the tRNA Prenyltransferase MiaA Controls the Stress Resistance and Virulence Potential of Extraintestinal Pathogenic Escherichia coli
Blango, M. G.; Fleming, B. A.; Kincannon, W. M.; Tran, A.; Lewis, A. J.; Russell, C. W.; Zhou, Q.; Baird, L. M.; Brannon, J. R.; Beebout, C. J.; Bandarian, V.; Hadjifraniskou, M.; Howard, M. T.; Mulvey, M. A.
10.1101/2021.02.02.429414 — microbiology — Posted on 2021-02-02
3991 Dynamic modulation of spleen germinal center reactions by gut bacteria during Plasmodium infection
Mandal, R. K.; Denny, J. E.; Namazzi, R.; Opoka, R. O.; Datta, D.; John, C. C.; Schmidt, N. W.
10.1101/2021.02.02.429404 — immunology — Posted on 2021-02-02
3992 Comparing synaptic proteomes across seven mouse models for autism reveals molecular subtypes and deficits in Rho GTPase signaling
Carbonell, A. U.; Freire-Cobo, C.; Deyneko, I. V.; Erdjument-Bromage, H.; Clipperton-Allen, A.; Rasmusson, R.; Page, D. T.; Neubert, T. A.; Jordan, B. A.
10.1101/2021.02.02.429412 — neuroscience — Posted on 2021-02-02
3993 Midbrain microglia exhibit early proliferative and inflammatory responses during aging that are modulated by CX3CR1 and microglial ablation and repopulation
Moca, E. N.; Lecca, D.; Hope, K. T.; Tweedie, D.; Sidhu, S.; Masukawa, L.; Sitoy, H.; Mathew, R.; Saban, D.; Greig, N. H.; De Biase, L. M.
10.1101/2021.02.02.429070 — neuroscience — Posted on 2021-02-02
3994 Severe deficiency of voltage-gated sodium channel NaV1.2 elevates neuronal excitability in adult mice
Zhang, J.; Chen, X.; Eaton, M.; Lai, S.; Park, A.; Ahmad, T. S.; Wu, J.; Ma, Z.; Que, Z.; Hea Lee, J.; Xiao, T.; Li, Y.; Wang, Y.; Olivero-Acosta, M. I.; Schaber, J. A.; Jayant, K.; Huang, Z.; Lanman, N. A.; Skarnes, W. C.; Yang, Y.
10.1101/2021.02.02.429384 — neuroscience — Posted on 2021-02-02
4002 Spc1 regulates substrate selection for signal peptidase
Yim, C.; Chung, Y.; Kim, J.; Nilsson, I.; Kim, J.-S.; Kim, H.
10.1101/2021.02.02.429376 — biochemistry — Posted on 2021-02-02
4004 The basis of a more contagious 501Y.V1 variant of SARS-COV-2
Zhang, G.; Liu, H.; Zhang, Q.; Wei, P.; Chen, Z.; Aviszus, K.; Yang, J.; Downing, W.; Peterson, S.; Jiang, C.; Liang, B.; Reynoso, L.; Downey, G.; Frankel, S.; Kapper, J.; Marrack, P.
10.1101/2021.02.02.428884 — biochemistry — Posted on 2021-02-02
4006 Population size mediates the contribution of high-rate and large-benefit mutations to parallel evolution
Schenk, M. F.; Zwart, M. P.; Hwang, S.; Ruelens, P.; Severing, E.; Krug, J.; de Visser, J. A. G. M.
10.1101/2021.02.02.429281 — evolutionary biology — Posted on 2021-02-02
4007 Improved accuracy for automated counting of a fish in baited underwater videos for stock assessment
Connolly, R.; Fairclough, D.; Jinks, E.; Ditria, E.; Jackson, G.; Lopez-Marcano, S.; Olds, A.; Jinks, K.
10.1101/2021.02.01.429285 — ecology — Posted on 2021-02-02
4009 Deep Proteome Profiling of Human Mammary Epithelia at Lineage and Age Resolution
Hinz, S.; Manousopoulou, A.; Miyano, M.; Sayaman, R. W.; Aguilera, K. Y.; Todhunter, M. E.; Lopez, J. C.; Sohn, L. L.; Wang, L. D.; LaBarge, M. A.
10.1101/2021.02.02.429276 — cell biology — Posted on 2021-02-02
4010 RNA-Sequencing of Long-Term Label-Retaining Colon Cancer Stem Cells Identifies Novel Regulators of Quiescence
Regan, J. L.; Schumacher, D.; Staudte, S.; Steffen, A.; Lesche, R.; Toedling, J.; Jourdan, T.; Haybaeck, J.; Mumberg, D.; Henderson, D.; Gyorffy, B.; Regenbrecht, C. R. A.; Keilholz, U.; Schafer, R.; Lange, M.
10.1101/2021.02.02.429354 — cell biology — Posted on 2021-02-02
4012 Spatial-proteomics reveal in-vivo phospho-signaling dynamics at subcellular resolution
Martinez del Val, A.; Bekker-Jensen, D. B.; Steigerwald, S.; Mehta, A.; Tran, T.; Sikorski, K.; Torres-Vega, E.; Kwasniewicz, E.; Hlin Brynjolfsdottir, S.; Frankel, L. B.; Kjobsted, R.; Krogh, N.; Lundby, A.; Bekker-Jensen, S.; Lund-Johansen, F.; Olsen, J. V.
10.1101/2021.02.02.425898 — systems biology — Posted on 2021-02-02
4014 Transport engineering for improving production and secretion of valuable alkaloids in Escherichia coli
Yamada, Y.; Urui, M.; Oki, H.; Inoue, K.; Matsui, H.; Ikeda, Y.; Nakagawa, A.; Sato, F.; Minami, H.; Shitan, N.
10.1101/2021.02.01.429260 — synthetic biology — Posted on 2021-02-02
4015 Resolving phylogenetic and biochemical barriers to functional expression of heterologous iron-sulphur cluster enzymes
Shomar, H.; Garcia, P. S.; Fernandez-Fueyo, E.; D'Angelo, F.; Pelosse, M.; Manuel, R. R.; Büke, F.; Liu, S.; van den Broek, N.; Duraffourg, N.; de Ram, C.; Pabst, M.; Gribaldo, S.; Py, B.; Ollagnier de Choudens, S.; Bokinsky, G.; Barras, F.
10.1101/2021.02.02.429153 — synthetic biology — Posted on 2021-02-02
4016 Bioprinting transgenic plant cells for production of a recombinant biodefense agent
Varma, A.; Gemeda, H. B.; McNulty, M. J.; McDonald, K.; Nandi, S.; Knipe, J.
10.1101/2021.02.01.429263 — plant biology — Posted on 2021-02-02
4019 Chemical screen identifies a small molecule antagonizing JA-Ile perception and auxin responses.
Chini, A.; Monte, I.; Fernandez-Barbero, G.; Boter, M.; Hicks, G.; Raikhel, N. V.; Solano, R.
10.1101/2021.02.02.429350 — plant biology — Posted on 2021-02-02
4020 PolyQ expansion does not alter the Huntingtin-HAP40 complex
Huang, B.; Guo, Q.; Niedermeier, M. L.; Cheng, J.; Engler, T.; Maurer, M.; Pautsch, A.; Baumeister, W.; Stengel, F.; Kochanek, S.; Fernandez-Busnadiego, R.
10.1101/2021.02.02.429316 — biophysics — Posted on 2021-02-02
4026 Functionalized extracellular matrix scaffolds loaded with endothelial progenitor cells promote neovascularization and diabetic wound healing
He, S.; Walimbe, T.; Chen, H.; Gao, K.; Kumar, P.; Wei, Y.; Hao, D.; Liu, R.; Farmer, D. L.; Lam, K.; Zhou, J.; Panitch, A.; Wang, A.
10.1101/2021.02.02.429318 — bioengineering — Posted on 2021-02-02
4027 How coiled-coil assemblies accommodate multiple aromatic residues
Rhys, G. G.; Dawson, W. M.; Beesley, J. L.; Martin, F. J. O.; Brady, L.; Thomson, A. R.; Woolfson, D. N.
10.1101/2021.02.01.429152 — biochemistry — Posted on 2021-02-02
4028 Validation and classification of RNA binding proteins identified by mRNA interactome capture
Vaishali, V.; Dimitrova-Paternoga, L.; Haubrich, K.; Sun, M.; Ephrussi, A.; Hennig, J.
10.1101/2021.02.02.429302 — biochemistry — Posted on 2021-02-02
4032 Identification of a Nervous System Gene Expression Signature in Colon Cancer Stem Cells Reveals a Role for Neural Crest Regulators EGR2 and SOX2 in Tumorigenesis
Regan, J. L.; Schumacher, D.; Staudte, S.; Steffen, A.; Lesche, R.; Toedling, J.; Jourdan, T.; Haybaeck, J.; Golob-Schwarzl, N.; Mumberg, D.; Henderson, D.; Gyorffy, B.; Regenbrecht, C. R. A.; Keilholz, U.; Schafer, R.; Lange, M.
10.1101/2021.02.02.428317 — cell biology — Posted on 2021-02-02
4033 Super-resolved local recruitment of CLDN5 to filtration slits implicates a direct relationship with podocyte foot process effacement
Tesch, F.; Siegerist, F.; Hay, E.; Artelt, N.; Daniel, C.; Amann, K.; Zimmermann, U.; Kavvadas, P.; Grisk, O.; Chadjichristos, C.; Endlich, K.; Chatziantoniou, C.; Endlich, N.
10.1101/2021.02.02.429338 — cell biology — Posted on 2021-02-02
4037 Perturbations in 3D genome organization can promote acquired drug resistance
Manjon, A. G.; Peric-Hupkes, D.; Liu, N. Q.; Friskes, A.; Joosten, S.; Teunissen, H.; Aarts, M.; Prekovic, S.; Zwart, W.; de Wit, E.; van Steensel, B.; Medema, R. H.
10.1101/2021.02.02.429315 — molecular biology — Posted on 2021-02-02
4041 Phenotypic and genotypic characterization of antibiotic Resistant Gram Negative Bacteria isolated in Tabuk City, Saudi Arabia
Alnour, T. M.; Elssaig, E. H.; Ahmed-Abakur, E. H.; Abuduhier, F. M.; Alfifi, K. A. S.; Abusuliman, M. S.; Albalawi, T.
10.1101/2021.02.01.429288 — microbiology — Posted on 2021-02-02
4042 Potential Early Rabies Infection Detected in Two Raccoon Cases by LN34 pan-lyssavirus real-time RT-PCR Assay in Pennsylvania
Dettinger, L.; Gigante, C. M.; Strohecker, M.; Seiders, M.; Patel, P.; Orciari, L. A.; Yager, P.; Lute, J.; Regec, A.; Li, Y.; Xia, D.
10.1101/2021.02.01.429287 — microbiology — Posted on 2021-02-02
4043 Spatial and temporal plasticity of neoantigen-specific T-cell responses bases on characteristics associated to antigen and TCR
Braeunlein, E.; Lupoli, G.; Abalrous, E. T.; de Andrade Kraetzig, N.; Gosmann, D.; Fuechsl, F.; Wietbrock, L.; Lange, S.; Engleitner, T.; Lan, H.; Audehm, S.; Effenberger, M.; Boxberg, M.; Steiger, K.; Chang, Y.; Yu, K.; Atay, C.; Bassermann, F.; Weichert, W.; Busch, D. H.; Rad, R.; Freund, C.; Antes, I.; Krackhardt, A. M.
10.1101/2021.02.02.428777 — immunology — Posted on 2021-02-02
4045 Cortico-amygdalar connectivity and externalizing/internalizing behavior in children with neurodevelopmental disorders
Nakua, H.; Hawco, C.; Forde, N. J.; Jacobs, G. R.; Joseph, M.; Voineskos, A.; Wheeler, A. L.; Lai, M.-C.; Szatmari, P.; Kelley, E.; Liu, X.; Georgiades, S.; Nicolson, R.; Schachar, R.; Crosbie, J.; Anagnostou, E.; Lerch, J. P.; Arnold, P. D.; Ameis, S. H.
10.1101/2021.02.01.429143 — neuroscience — Posted on 2021-02-02
4046 Protein lactylation induced by neural excitation
Hagihara, H.; Shoji, H.; Otabi, H.; Toyoda, A.; Katoh, K.; Namihira, M.; Miyakawa, T.
10.1101/2021.02.02.428370 — neuroscience — Posted on 2021-02-02
4049 WILMS TUMORIGENESIS IN HUMAN KIDNEY ORGANOIDS
Waehle, V.; Ungricht, R.; Hoppe, P. S.; Betschinger, J.
10.1101/2021.02.02.429313 — cancer biology — Posted on 2021-02-02
4050 In vivo amyloid-like fibrils produced under stress
Fontana, N. A.; Rosse, A. D.; Watts, A.; Coelho, P. S. R.; Costa-Filho, A. J.
10.1101/2021.02.02.429251 — biophysics — Posted on 2021-02-02
4053 ChIPuana: from raw data to epigenomic dynamics
Daunesse, M.; Legendre, R.; Varet, H.; Pain, A.; Chica, C.
10.1101/2021.02.02.429342 — bioinformatics — Posted on 2021-02-02
4055 Increased levels of the mitochondrial import factor Mia40 prevent the aggregation of polyQ proteins in the cytosol
Schlagowski, A. M.; Knöringer, K.; Morlot, S.; Sachez Vicente, A.; Boos, F.; Khalid, N.; Ahmed, S.; Schramm, J.; Murschall, L. M.; Haberkant, P.; Stein, F.; Riemer, J.; Westermann, B.; Braun, R. J.; Winklhofer, K. F.; Charvin, G.; Herrmann, J. M.
10.1101/2021.02.02.429331 — biochemistry — Posted on 2021-02-02
4056 Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors
Pandey, S.; Kumari, P.; Baidya, M.; Kise, R.; Cao, Y.; Dwivedi-Agnihotri, H.; Banerjee, R.; Li, X.; Cui, C.; Lee, J.; Kawakami, K.; Chaturvedi, M.; Ranjan, A.; Laporte, S.; Woodruff, T. M.; Inoue, A.; SHUKLA, A. K.
10.1101/2021.02.02.429298 — biochemistry — Posted on 2021-02-02
4058 Endothelial cell senescence exacerbates pulmonary hypertension through Notch-mediated juxtacrine signaling
Ramadhiani, R.; Ikeda, K.; Miyagawa, K.; Ryanto, G. R. T.; Tamada, N.; Suzuki, Y.; Hirata, K.-i.; Emoto, N.
10.1101/2021.02.02.429321 — cell biology — Posted on 2021-02-02
4062 Therapeutic antibodies, targeting the SARS-CoV-2 spike N-terminal domain, protect lethally infected K18-hACE2 mice
Noy-Porat, T.; Mechaly, A.; Levy, Y.; Makdasi, E.; Alcalay, R.; Gur, D.; Aftalion, M.; Falach, R.; Leviatan Ben-Arye, S.; Lazar, S.; Zauberman, A.; Epstein, E.; Chitlaru, T.; Weiss, S.; Achdout, H.; Edgeworth, J. D.; Kikkeri, R.; Yu, H.; Chen, X.; Yitzhaki, S.; Shapira, S. C.; Padler-Karavani, V.; Mazor, O.; Rosenfeld, R.
10.1101/2021.02.02.428995 — immunology — Posted on 2021-02-02
4063 Paradoxical hyperexcitability from NaV1.2 sodium channel loss in neocortical pyramidal cells
Spratt, P. W.; Ben-Shalom, R.; Sahagun, A.; Keeshen, C. M.; Sanders, S. J.; Bender, K. J.
10.1101/2021.02.02.429423 — neuroscience — Posted on 2021-02-02
4064 Cofilin pathology is a new player on α-synuclein-induced spine impairment in models of hippocampal synucleinopathy
Oliveira da Silva, M. I.; Santejo, M.; Babcock, I. W.; Magalhaes, A.; Minamide, L. S.; Castillo, E.; Gerhardt, E.; Fahlbusch, C.; Swanson, R. A.; Outeiro, T. F.; Bamburg, J. R.; Liz, M. A.
10.1101/2021.02.02.425931 — neuroscience — Posted on 2021-02-02
4066 A Thermostable, Flexible RNA Vaccine Delivery Platform for Pandemic Response
Gerhardt, A.; Voigt, E.; Archer, M.; Reed, S.; Larson, E.; Van Hoeven, N.; Kramer, R.; Fox, C.; Casper, C.
10.1101/2021.02.01.429283 — bioengineering — Posted on 2021-02-02
4067 Resveratrol And Pterostilbene Potently Inhibit SARS-CoV-2 Replication In Vitro
ter Ellen, B. M.; Dinesh Kumar, N.; Bouma, E. M.; Troost, B.; van de Pol, D. P. I.; van der Ende-Metselaar, H. H.; Apperloo, L.; van Gosliga, D.; van den Berge, M.; Nawijn, M. C.; van der Voort, P. H. J.; Moser, J.; Rodenhuis-Zybert, I. A.; Smit, J. M.
10.1101/2020.09.24.285940 — microbiology — Posted on 2021-02-02
4068 Identification of bis-benzylisoquinoline alkaloids as SARS-CoV-2 entry inhibitors from a library of natural products in vitro
He, C.-L.; Huang, L.-Y.; Wang, K.; Gu, C.-J.; Hu, J.; Zhang, G.-J.; Xu, W.; Xie, Y.-H.; Tang, N.; Huang, A.-L.
10.1101/2020.12.13.420406 — microbiology — Posted on 2021-02-02
4070 Molecular mechanism of N-terminal acetylation by the ternary NatC complex
Deng, S.; Gottlieb, L.; Pan, B.; Supplee, J.; Wei, X.; Petersson, J.; Marmorstein, R.
10.1101/2021.02.01.429250 — biophysics — Posted on 2021-02-02
4074 Spray-induced gene silencing for disease control is dependent on the efficiency of pathogen RNA uptake
Qiao, L.; Lan, C.; Capriotti, L.; Ah-Fong, A.; Nino Sanchez, J.; Hamby, R.; Heller, J.; Zhao, H.; Glass, N. L.; Judelson, H. S.; Mezzetti, B.; Niu, D.; Jin, H.
10.1101/2021.02.01.429265 — microbiology — Posted on 2021-02-02
4076 Working Memory Representations in Visual Cortex Mediate the Effects of Distraction
Hallenbeck, G. E.; Sprague, T. C.; Rahmati, M. C.; Sreenivasan, K. K.; Curtis, C. E.
10.1101/2021.02.01.429259 — neuroscience — Posted on 2021-02-02
4079 Mutant SETBP1 enhances NRAS-driven MAPK pathway activation to promote aggressive leukemia
Carratt, S. A.; Braun, T. P.; Coblentz, C.; Schonrock, Z.; Callahan, R.; Smith, B. M.; Maloney, L.; Foley, A.; Maxson, J. E.
10.1101/2021.02.01.429244 — cancer biology — Posted on 2021-02-02
4083 The ETS Transcription Factor ERF controls the exit from the naive pluripotent state
Vega-Sendino, M.; Olbrich, T.; Tillo, D.; Tran, A. D.; Domingo, C. N.; Franco, M.; FitzGerald, P. C.; Kruhlak, M.; Ruiz Macias, S.
10.1101/2021.02.01.429223 — developmental biology — Posted on 2021-02-02
4085 Stage-specific, morphological and molecular markers of encystation in Giardia lamblia
Thomas, E. B.; Sutanto, R.; Johnson, R. S.; Shih, H.-W.; Krtkova, J.; MacCoss, M. J.; Paredez, A. R.
10.1101/2021.02.01.429238 — cell biology — Posted on 2021-02-02
4087 Chemogenetic dissection of the primate prefronto-subcortical pathways for working memory and decision-making
Oyama, K.; Hori, Y.; Nagai, Y.; Miyakawa, N.; Mimura, K.; Hirabayashi, T.; Inoue, K.-i.; Suhara, T.; Takada, M.; Higuchi, M.; Minamimoto, T.
10.1101/2021.02.01.429248 — neuroscience — Posted on 2021-02-02
4088 Colonization at birth with human CST IV cervicovaginal microbiota alters development and increases neonatal mortality in mice
Jasarevic, E.; Hill, E. M.; Kane, P. J.; Rutt, L.; Gyles, T.; Folts, L.; Rock, K. D.; Howard, C. D.; Morrison, K. E.; Ravel, J.; Bale, T. L.
10.1101/2021.02.01.429213 — systems biology — Posted on 2021-02-02
4089 Basal-to-classical phenotypic switch of pancreatic cancer cells upon integration into the duodenal epithelium
Bozoky, B.; Fernandez Moro, C.; Strell, C.; Ernberg, I.; Szekely, L.; Gerling, M.; Bozoky, B.
10.1101/2021.02.01.429212 — cancer biology — Posted on 2021-02-02
4090 Variation in Placental microRNA Expression Associates with Familial Cardiovascular Disease
Tehrani, J. M.; Kennedy, E. M.; Tian, F.-Y.; Everson, T. M.; Deyssenroth, M.; Burt, A.; Hermetz, K.; Hao, K.; Chen, J.; Koestler, D. C.; Marsit, C. J.
10.1101/2021.02.01.429202 — genetics — Posted on 2021-02-02
4092 Impact of a human gut microbe on Vibrio cholerae host colonization through biofilm enhancement
Barrasso, K.; Chac, D.; Debele, M. D.; Harris, J. B.; LaRocque, R. C.; Midani, F. S.; Qadri, F.; Yan, J.; Weil, A. A.; Ng, W.-L.
10.1101/2021.02.01.429194 — microbiology — Posted on 2021-02-02
4094 RIM and RIM-binding protein localize synaptic Cav2 channels in a differential manner to regulate transmission in neuronal circuits
Janosi, B.; Liewald, J. F.; Yu, S.-c.; Umbach, S.; Alcantara, I. C.; Bergs, A. C.; Schneider, M. W.; Shao, J.; Gottschalk, A.
10.1101/2021.02.01.429206 — neuroscience — Posted on 2021-02-02
4096 Isolation and in vitro culture of primary pia mater cells
Saadeh, F.; Remsik, J.; Derderian, C.; Chi, Y.; Boire, A.
10.1101/2021.02.01.429222 — neuroscience — Posted on 2021-02-02
4102 Single-nuclei RNA-sequencing of plant tissues
Sunaga-Franze, D. Y.; Muino, J.; Braeuning, C.; Xu, X.; Zong, M.; Smaczniak, C.; Yan, W.; Fischer, C.; Vidal, R.; Kliem, M.; Kaufmann, K.; Sauer, S.
10.1101/2020.11.14.382812 — genomics — Posted on 2021-02-02
4103 Neuronal control of maternal provisioning in response to social cues
Wasson, J. A.; Harris, G.; Keppler-Ross, S.; Brock, T. J.; Dar, A. R.; Butcher, R. A.; Fischer, S. E. J.; Kagias, K.; Clardy, J.; Zhang, Y.; Mango, S. E.
10.1101/2021.02.01.429208 — genetics — Posted on 2021-02-02
4104 Evolution of flowering time in a selfing annual plant: Roles of adaptation and genetic drift
Gay, L.; Dhinaut, J.; Jullien, M.; Vitalis, R.; Navascues, M.; Ranwez, V.; Ronfort, J.
10.1101/2020.08.21.261230 — evolutionary biology — Posted on 2021-02-02
4107 Climate warming changes synchrony of plants and pollinators
Freimuth, J.; Bossdorf, O.; Scheepens, J. F.; Willems, F. M.
10.1101/2021.01.10.425984 — ecology — Posted on 2021-02-02
4109 The ATF6β-calreticulin axis protects hippocampal neurons against endoplasmic reticulum stress and excitotoxicity
Nguyen, D. T.; Le, T. M.; Hattori, T.; Takarada-Iemata, M.; Ishii, H.; Roboon, J.; Tamatani, T.; Kannon, T.; Hosomichi, K.; Tajima, A.; Taniuchi, S.; Miyake, M.; Oyadomari, S.; Saito, S.; Mori, K.; Hori, O.
10.1101/2021.02.01.429116 — cell biology — Posted on 2021-02-02
4111 Immune complex solubility and size govern individual Fc-gamma receptor responses: Novel biomarkers for autoimmune diseases
Chen, H.; Maul-Pavicic, A.; Holzer, M.; Salzer, U.; Chevalier, N.; Voll, R. E.; Hengel, H.; Kolb, P.
10.1101/2020.11.11.378232 — immunology — Posted on 2021-02-02
4112 Microglia control glutamatergic synapses in the adult mouse hippocampus
Basilico, B.; Ferrucci, L.; Ratano, P.; Golia, M. T.; Grimaldi, A.; Rosito, M.; Ferretti, V.; Reverte, I.; Marrone, M. C.; Giubettini, M.; de Turris, V.; Salerno, D.; Garofalo, S.; St-Pierre, M.-K.; Carrier, M.; Renzi, M.; Pagani, F.; Raspa, M.; Scavizzi, F.; Gross, C. T.; Marinelli, S.; Tremblay, M.-E.; Caprioli, D.; Maggi, L.; Limatola, C.; Di Angelantonio, S.; Ragozzino, D.
10.1101/2021.02.01.429096 — neuroscience — Posted on 2021-02-02
4113 Maladaptive cue-controlled cocaine-seeking habits promote increased relapse severity in rats.
Fouyssac, M.; Pena-Oliver, Y.; Puaud, M.; Lim, N.; Giuliano, C.; Everitt, B. J.; Belin, D.
10.1101/2021.02.01.429216 — neuroscience — Posted on 2021-02-02
4114 Glucose-dependent activation, activity, and deactivation of beta cell networks in acute mouse pancreas tissue slices
Stozer, A.; Skelin Klemen, M.; Gosak, M.; Krizancic-Bombek, L.; Pohorec, V.; Slak Rupnik, M.; Dolensek, J.
10.1101/2020.03.11.986893 — physiology — Posted on 2021-02-02
4115 A specific agonist of the orphan nuclear receptor NR2F1 suppresses metastasis through the induction of cancer cell dormancy
Khalil, B. D.; Sanchez, R.; Rahman, T.; Rodriguez-Tirado, C. A.; Moritsch, S.; Rodriguez Martinez, A.; Miles, B.; Farias, E.; Mezei, M.; Cheung, J. F.; Nobre, A. R.; Kale, N.; Sproll, K. C.; Sosa, M. S.; Aguirre-Ghiso, J. A.
10.1101/2021.01.30.428967 — cancer biology — Posted on 2021-02-02
4119 Cell type specific information transfer for sparse coding
Zeldenrust, F.; Calcini, N.; Yan, X.; Bijlsma, A.; Celikel, T.
10.1101/2020.11.06.371658 — neuroscience — Posted on 2021-02-02
4120 Transparent and flexible ECoG electrode arrays based on silver nanowire networks for neural recordings
Neto, J. P.; Costa, A.; Pinto, J. V.; Marques-Smith, A.; Costa, J.; Martins, R.; Fortunato, E.; Kampff, A. R.; Barquinha, P.
10.1101/2020.02.24.962878 — neuroscience — Posted on 2021-02-02
4122 Regenerating insulin-producing β-cells ectopically from a mesodermal origin in the absence of endothelial specification
Liu, K.-C.; Villasenor, A.; Schmitner, N.; Radros, N.; Rautio, L.; Reischauer, S.; Stainier, D. Y.; Andersson, O.
10.1101/2021.02.01.429189 — developmental biology — Posted on 2021-02-02
4123 Agricultural fertilization with poultry manure results in persistent environmental contamination with the pathogen Clostridioides difficile
Frentrup, M.; Thiel, N.; Junker, V.; Behrens, W.; Munch, S.; Siller, P.; Kabelitz, T.; Faust, M.; Indra, A.; Baumgartner, S.; Schepanski, K.; Amon, T.; Roesler, U.; Funk, R.; Nubel, U.
10.1101/2021.02.01.429155 — microbiology — Posted on 2021-02-02
4125 Rapid fall in circulating non-classical monocytes in ST elevation myocardial infarction patients correlates with cardiac injury
Marsh, S.; Park, C.; Redgrave, R. E.; Singh, E.; Draganova, L. V.; Boag, S. E.; Spray, L.; Ali, S.; Spyridopoulos, I.; Arthur, H. M.
10.1101/2021.02.01.428825 — immunology — Posted on 2021-02-02
4126 Phase Gradients and Anisotropy of the Suprachiasmatic Network
Yoshikawa, T.; Pauls, S. D.; Foley, N.; Taub, A.; LeSauter, J.; Foley, D.; Honma, K.-I.; Honma, S.; Silver, R.
10.1101/2021.02.01.429173 — neuroscience — Posted on 2021-02-02
4127 Environmental enrichment induces epigenomic and genome organization changes relevant for cognitive function
Espeso-Gil, S.; Holik, A.; Bonnin, S.; Jhanwar, S.; Chandrasekaran, S.; Pique-Regi, R.; Albaiges-Rafols, J.; Maher, M.; Permanyer, J.; Irimia, M.; Friedländer, M. R.; Pons-Espinal, M.; Akbarian, S.; Dierssen, M.; Maass, P. G.; Hor, C. N.; Ossowski, S.
10.1101/2021.01.31.428988 — neuroscience — Posted on 2021-02-02
4128 Complementary Maps for Location and Environmental Structure in CA1 and Subiculum
Olson, J. M.; Johnson, A. B.; Chang, L.; Tao, E. L.; Wang, X.; Nitz, D. A.
10.1101/2021.02.01.428537 — neuroscience — Posted on 2021-02-02
4129 Learning and attention increase visual response selectivity through distinct mechanisms
Poort, J.; Wilmes, K. A.; Blot, A.; Chadwick, A.; Sahani, M.; Clopath, C.; Mrsic-Flogel, T. D.; Hofer, S. B.; Khan, A. G.
10.1101/2021.01.31.429053 — neuroscience — Posted on 2021-02-02
4130 Cubam receptor-mediated endocytosis in hindgut-derived pseudoplacenta of a viviparous teleost Xenotoca eiseni
Iida, A.; Sano, K.; Inokuchi, M.; Suzuki, T.; Kuriki, M.; Sogabe, M.; Susaki, D.; Tonosaki, K.; Kinoshita, T.; Hondo, E.
10.1101/2021.02.01.429082 — zoology — Posted on 2021-02-02
4132 The Reactobiome Unravels a New Paradigm in Human Gut Microbiome Metabolism
Bidkhori, G.; Lee, S.; Edwards, L.; Chatelier, E. L.; Almeida, M.; Ezzamouri, B.; Plaza -Onate, F.; Ponte, N.; Shawcross, D.; Proctor, G. B.; Nielsen, L.; Nielsen, J.; Uhlen, M.; Dusko Ehrlich, S.; Shoaie, S.
10.1101/2021.02.01.428114 — systems biology — Posted on 2021-02-02
4133 ESD1 Affects Seed Setting Rate in Rice by Controlling Embryo Sac Development
Wang, T.; Li, Y.; Song, S.; Qiu, M.; Zhang, L.; Li, C.; Dong, H.; Li, L.; Wang, J.; Li, L.
10.1101/2021.02.01.429182 — plant biology — Posted on 2021-02-02
4140 A catalogue of omics biological ageing clocks reveals substantial commonality and associations with disease risk
Macdonald-Dunlop, E.; Taba, N.; Klaric, L.; Frkatovic, A.; Walker, R.; Hayward, C.; Esko, T.; Haley, C.; Fischer, K.; Wilson, J. F.; Joshi, P. K.
10.1101/2021.02.01.429117 — bioinformatics — Posted on 2021-02-02
4141 LoopViz: A uLoop Assembly Clone Verification Tool for Nanopore Sequencing Reads
Lensink, M. E.; Abramson, B.; Hartwick, N.; Poire, A.; Bielinski, V. A.; Michael, T.
10.1101/2021.02.01.427927 — bioinformatics — Posted on 2021-02-02
4143 Single-component optogenetic tools for inducible RhoA GTPase signaling
Berlew, E. E.; Kuznetsov, I. A.; Yamada, K. K.; Bugaj, L. J.; Boerckel, J. D.; Chow, B. Y.
10.1101/2021.02.01.429147 — bioengineering — Posted on 2021-02-02
4145 Comparative genomics of Chinese and international isolates of Escherichia albertii: population structure and evolution of virulence and antimicrobial resistance
Luo, L.; Wang, H.; Payne, M. J.; Liang, C.; Bai, L.; Zheng, H.; Zhang, Z.; Zhang, L.; Zhang, X.; Yan, G.; Zou, N.; Chen, X.; Wan, Z.; Xiong, Y.; Lan, R.; Li, Q.
10.1101/2021.02.01.429068 — genomics — Posted on 2021-02-02
4147 Hybridization dynamics and extensive introgression in the Daphnia longispina species complex: new insights from a high-quality Daphnia galeata reference genome
Nickel, J. H.; Schell, T.; Holtzem, T.; Thielsch, A.; Dennis, S. R.; Schlick-Steiner, B.; Steiner, F. M.; Moest, M.; Pfenninger, M.; Schwenk, K.; Cordellier, M.
10.1101/2021.02.01.429177 — evolutionary biology — Posted on 2021-02-02
4156 Long noncoding RNA VENTHEART is required for cardiomyocyte specification and function
Foo, R.; Dashi, A.; Lek Wen, T. W.; Anene, G.; Pan, b.; Autio, M. I.; Tiang, Z.; Hartman, R.; Stenzig, J.; Wei, H.; Chen, G.; Ackers-Johnson, M.; Jonsson, M.; Walentinsson, A.; Lim, B.; Iyer, V.
10.1101/2021.02.01.429136 — cell biology — Posted on 2021-02-02
4157 Mouse oocytes do not contain a conventional Balbiani body
Dhandapani, L.; Salzer, M.; Duran, J. M.; Zaffagnini, G.; De Guirior, C.; Martinez-Zamora, M. A.; Boke, E.
10.1101/2021.02.01.429160 — cell biology — Posted on 2021-02-02
4158 EMC is required for biogenesis and membrane insertion of Xport-A, an essential chaperone of rhodopsin-1 and the TRP channel
Gaspar, C. J.; Vieira, L. C.; Christianson, J. C.; Jakubec, D.; Strisovsky, K.; Adrain, C.; Domingos, P.
10.1101/2021.02.01.429115 — cell biology — Posted on 2021-02-02
4159 Molecular mechanism behind the involvement of apple flavonoid glycosyltransferase gene MdGT1 in the color of apple leaves
Li, P.; Ge, H.; Zhang, L.; Shu, J.; Sun, Z.; Jiang, L.; Zheng, C.-C.; Shu, H.; Sha, G.; Ji, L.; Zhang, S.
10.1101/2021.02.01.429094 — molecular biology — Posted on 2021-02-02
4162 Heliorhodopsin evolution is driven by photosensory promiscuity in monoderms
Bulzu, P.-A.; Kavagutti, V. S.; Chiriac, M.-C.; Vavourakis, C.; Inoue, K.; Kandori, H.; Andrei, A.-S.; Ghai, R.
10.1101/2021.02.01.429150 — microbiology — Posted on 2021-02-02
4164 Quality control strategies for brain MRI segmentation and parcellation: practical approaches and recommendations - insights from The Maastricht Study
Monereo Sanchez, J.; de Jong, J.; Drenthen, G.; Beran, M.; Backes, W.; Stehouwer, C.; Schram, M.; Linden, D.; Jansen, J.
10.1101/2021.02.01.428681 — neuroscience — Posted on 2021-02-02
4167 Increasing age is independently associated with higher free water in non-active MS brain - A multi-compartment analysis using FAST-T2
Zhou, L.; Li, Y.; Wang, X. H.; Sweeney, E.; Zhang, H.; Tanzi, E. B.; Prince, J.; Su-Ortiz, V. A.; Gauthier, S. A.; Nguyen, T. D.
10.1101/2021.02.01.429067 — neuroscience — Posted on 2021-02-02
4170 Transcriptomics-informed large-scale cortical model captures topography of pharmacological neuroimaging effects of LSD
Burt, J. B.; Preller, K. H.; Demirtas, M.; Ji, J. L.; Krystal, J. H.; Vollenweider, F. X.; Anticevic, A.; Murray, J. D.
10.1101/2021.01.31.429016 — neuroscience — Posted on 2021-02-02
4173 Metabolomic profiling of pancreatic adenocarcinoma reveals fundamental clinical features
IOVANNA, J. L.; El kaoutari, A.; Fraunhoffer, N.; Hoare, O.; Teyssedou, C.; Gayet, O.; Roques, J.; Lomberk, G. A.; Urrutia, R. A.; Dusetti, N. J.
10.1101/2021.02.01.429087 — cancer biology — Posted on 2021-02-02
4175 Modelling TGFβR and Hh pathway regulation of prognostic matrisome molecules in ovarian cancer
Delaine-Smith, R.; Maniati, E.; Malacrida, B.; Nichols, S.; Roozitalab, R.; Jones, R. R.; Lecker, L.; Pearce, O. M.; Knight, M. M.; Balkwill, F. R.
10.1101/2021.02.01.428374 — cancer biology — Posted on 2021-02-02
4178 Targeted therapy for LIMD1-deficient non-small cell lung cancer subtypes.
Davidson, K.; Grevitt, P.; Contreras, M.; Bridge, K. S.; Hermida, M.; Shah, K. M.; Mardakheh, F. K.; Stubbs, M.; Clarke, P. A.; Burke, R.; Casado-Izquierdo, P.; Cutillas, P. R.; Martin, S. A.; Sharp, T. V.
10.1101/2021.02.01.429178 — cancer biology — Posted on 2021-02-02
4179 Machine learning based cellular contractile force detection: a new approach to predict cell mechanics by images
Li, H.; Matsunaga, D.; Matsui, T. S.; Aosaki, H.; Inoue, K.; Doostmohammadi, A.; Deguchi, S.
10.1101/2021.02.01.429065 — biophysics — Posted on 2021-02-01
4180 Associations of weather fronts with pig reproduction and mortality
Reibling, T.; Hagstrand, L.; Maroti-Agots, A.; Barcza, Z.; Solymosi, N.
10.1101/2021.02.01.428991 — biophysics — Posted on 2021-02-02
4186 Molecular basis for two stereoselective Diels-Alderases that produce decalin skeletons
Fujiyama, K.; Kato, N.; Re, S.; Kinugasa, K.; Watanabe, K.; Takita, R.; Nogawa, T.; Hino, T.; Osada, H.; Sugita, Y.; Takahashi, S.; Nagano, S.
10.1101/2021.02.01.429105 — biochemistry — Posted on 2021-02-02
4188 Genomic Considerations for FHIR; eMERGE Implementation Lessons
Murugan, M.; Babb, L. J.; Taylor, C. O.; Rasmussen, L. V.; Freimuth, R. R.; Venner, E.; Yan, F.; Yi, V.; Granite, S. J.; Zouk, H.; Aronson, S. J.; Power, K.; Fedotov, A.; Crosslin, D. R.; Fasel, D.; Jarvik, G. P.; Hakonarson, H.; Bangash, H.; Kullo, I. J.; Connolly, J. J.; Nestor, J. G.; Caraballo, P. J.; Wei, W.; Wiley, K.; Rehm, H. L.; Gibbs, R. A.
10.1101/2021.01.31.429037 — genomics — Posted on 2021-02-01
4189 TRIM71 deficiency causes germ cell loss during mouse embryogenesis and promotes human male infertility
Torres-Fernández, L. A.; Emich, J.; Port, Y.; Mitschka, S.; Wöste, M.; Schneider, S.; Fietz, D.; Oud, M. S.; Di Persio, S.; Neuhaus, N.; Kliesch, S.; Hölzel, M.; Schorle, H.; Friedrich, C.; Tüttelmann, F.; Kolanus, W.
10.1101/2021.02.01.429172 — developmental biology — Posted on 2021-02-02
4190 Identification of Pectobacterium species isolated from the soft rot of tetecho (Neobuxbaumia tetetzo), a columnar cactus, and associated metagenomics
Vargas-Peralta, D.; Narvaez-Barragan, D.; De Sandozequi, A.; Segovia, L.; Martinez-Anaya, C.; Romero-Gutierrez, M.; David Alcaraz, L.; De la Torre Almaraz, R.
10.1101/2021.02.01.429127 — microbiology — Posted on 2021-02-01
4191 Task-specific elevation of motor learning by conjunctive transcranial direct current stimulation
Wang, Y.; Wang, J.-x.; Zhang, Q.-f.; Xiao, K.-w.; Wang, L.; Yu, Q.-p.; Xie, Q.; Poo, M.-m.; Wen, Y.
10.1101/2021.01.31.429080 — neuroscience — Posted on 2021-02-02
4192 In-land long-term culture of colonial ascidians
Wawrzyniak, M. K.; Matas Serrato, L. A.; Blanchoud, S.
10.1101/2021.01.31.429038 — zoology — Posted on 2021-02-01
4193 Energy content of anchovy and sardine using surrogate calorimetry methods
Campanini, C.; Albo-Puigserver, M.; Gerez, S.; Lloret-Lloret, E.; Gimenez, J.; Pennino, M. G.; Bellido, J. M.; Colmenero, A. I.; Coll, M.
10.1101/2021.02.01.429042 — physiology — Posted on 2021-02-01
4194 Protein SUMOylation is crucial for phagocytosis in Entamoeba histolytica trophozoites
Diaz-Hernandez, M.; Javier-Reyna, R.; Ortega-Soto, I.; Garcia-Rivera, G.; Montano, S.; Betanzos, A.; Orozco, E.
10.1101/2021.02.01.429131 — microbiology — Posted on 2021-02-01
4196 Hierarchical modelling of functional brain networks in population and individuals from big fMRI data
Farahibozorg, S.-R.; Bijsterbosch, J. D.; Gong, W.; Jbabdi, S.; Smith, S. M.; Harrison, S. J.; Woolrich, M. W.
10.1101/2021.02.01.428496 — neuroscience — Posted on 2021-02-01
4201 Development and validation of a cellular host response test as an early diagnostic for sepsis
Guillou, L.; Sheybani, R.; Jensen, A. E.; DiCarlo, D.; Caffery, T.; Thomas, C. B.; Shah, A. M.; Tse, H. T. K.; O'Neal, H. R.
10.1101/2021.02.01.429128 — bioengineering — Posted on 2021-02-01
4204 Structural analysis of viral ExoN domains reveals polyphyletic hijacking events
Cruz-Gonzalez, A.; Munoz-Velasco, I.; Cottom-Salas, W.; Becerra, A.; Campillo-Balderas, J. A.; Hernandez-Morales, R.; Vazquez-Salazar, A.; Jacome, R.; Lazcano, A.
10.1101/2021.02.01.429129 — evolutionary biology — Posted on 2021-02-01
4205 Spindle-slow oscillation coupling during sleep predicts sequence-based language learning
Cross, Z. R.; Helfrich, R. F.; Kohler, M. J.; Corcoran, A. W.; Coussens, S.; Zou-Williams, L.; Schlesewsky, M.; Gaskell, M. G.; Knight, R. T.; Bornkessel-Schlesewsky, I.
10.1101/2020.02.13.948539 — neuroscience — Posted on 2021-02-01
4207 Early, color-specific neural responses to object color knowledge
Retter, T. L.; Gao, Y.; Jiang, F.; Rossion, B.; Webster, M. A.
10.1101/2021.02.01.429104 — neuroscience — Posted on 2021-02-01
4211 The Giardia lamellipodium-like ventrolateral flange supports attachment and rapid cytokinesis
Hardin, W. R.; Alas, G. C. M.; Taparia, N.; Thomas, E. B.; Steele-Ogus, M.; Hvorecny, K. L.; Halpern, A. R.; Tumova, P.; Kollman, J. M.; Vaughan, J. C.; Sniadecki, N. J.; Paredez, A. R.
10.1101/2021.01.31.429041 — cell biology — Posted on 2021-02-01
4213 Dysregulation of PAX5 causes uncommitted B cell development and tumorigenesis in mice
Boast, B.; Helian, K.; Andrews, D.; Li, X.; Cho, V.; Closa, A.; Sutton, H. J.; Reed, J. H.; Bergmann, H.; Roots, C. M.; Yabas, M.; Barthel, N.; Omari, S. A.; Young, C.; Miosge, L. A.; Eyras, E.; Nutt, S. L.; Hein, N.; Hannan, K. M.; Cockburn, I. A.; Goodnow, C. C.; Enders, A.
10.1101/2021.01.29.428877 — immunology — Posted on 2021-02-01
4216 Host PDZ-containing proteins targeted by SARS-Cov-2
Caillet-Saguy, C.; Durbesson, F.; REZELJ, V. V.; Gogl, G.; Tran, Q. D.; Twizere, J.-C.; Vignuzzi, M.; Vincentelli, R.; Wolff, N.
10.1101/2021.02.01.429176 — biochemistry — Posted on 2021-02-01
4218 Drosophila functional screening of de novo variants in autism uncovers deleterious variants and facilitates discovery of rare neurodevelopmental diseases
Marcogliese, P. C.; Deal, S. L.; Andrews, J.; Harnish, J. M.; Bhavana, V. H.; Graves, H. K.; Jangam, S.; Luo, X.; Liu, N.; Bei, D.; Chao, Y.-H.; Hull, B.; Lee, P.-T.; Pan, H.; Longley, C. M.; Chao, H.-T.; Chung, H.; Haelterman, N. A.; Kanca, O.; Manivannan, S. N.; Rossetti, L. Z.; Gerard, A.; Schwaibold, E. M. C.; Guerrini, R.; Vetro, A.; England, E.; Murali, C. N.; Barakat, T. S.; van Dooren, M. F.; Wilke, M.; van Slegtenhorst, M.; Lesca, G.; Sabatier, I.; Chatron, N.; Brownstein, C. A.; Madden, J. A.; Agrawal, P. B.; Keller, R.; Pavinato, L.; Brusco, A.; Rosenfeld, J. A.; Marom, R.; Wangler,
10.1101/2020.12.30.424813 — genetics — Posted on 2021-02-01
4221 H3K4 Methylation in β-cells Prevents Transcriptional Downregulation and Variance Associated with Type 2 Diabetes
Vanderkruk, B.; Maeshima, N.; Pasula, D. J.; An, M.; Suresh, P.; Daniel, A.; McDonald, C. L.; Luciani, D. S.; Hoffman, B.
10.1101/2021.01.28.428651 — cell biology — Posted on 2021-02-01
4224 First isolation and genetic characterization of Puumala orthohantavirus strains from France
Vulin, J.; Murri, S.; Madrieres, S.; Galan, M.; Tatard, C.; Piry, S.; Vaccari, G.; D'agostino, C.; Charbonnel, N.; Castel, G.; Marianneau, P.
10.1101/2020.08.27.270181 — microbiology — Posted on 2021-02-01
4225 CXCR6 enforced retention promotes resident memory CD8 T cell-mediated immunosurveillance and control of ovarian cancer.
Muthuswamy, R.; McGray, A. R.; Battaglia, S.; He, W.; Miliotto, A.; Eppolito, C. A.; Litchy, B. D.; Shrikant, P.; Odunsi, K.; Odunsi, K.
10.1101/2020.12.02.401729 — immunology — Posted on 2021-02-01
4226 Paradoxical stabilization of relative position in moving frames
Özkan, M.; Anstis, S.; 't Hart, B. M.; Wexler, M.; Cavanagh, P.
10.1101/2021.01.23.427924 — neuroscience — Posted on 2021-02-01
4231 Inhalable textile microplastic fibers impair airway epithelial growth
van Dijk, F.; Song, S. S.; van Eck, G.; Wu, X. H.; Bos, S.; Boom, D.; Kooter, I.; Spierings, D. C. J. N.; Wardenaar, R.; Cole, M.; Salvati, A.; Gosens, R.; Melgert, B. N.
10.1101/2021.01.25.428144 — pharmacology and toxicology — Posted on 2021-02-01
4232 Evolution of a virus-like architecture and packaging mechanism in a repurposed bacterial protein
Tetter, S.; Terasaka, N.; Steinauer, A.; Bingham, R. J.; Clark, S.; Scott, A. J. P.; Patel, N.; Leibundgut, M.; Wroblewski, E.; Ban, N.; Stockley, P. G.; Twarock, R.; Hilvert, D.
10.1101/2020.12.23.423990 — biochemistry — Posted on 2021-02-01
4233 Diagnostic design with machine learning model-based optimization
Metsky, H. C.; Welch, N. L.; Haradhvala, N. J.; Rumker, L.; Zhang, Y. B.; Pillai, P. P.; Yang, D. K.; Ackerman, C. M.; Weller, J.; Blainey, P. C.; Myhrvold, C.; Mitzenmacher, M.; Sabeti, P. C.
10.1101/2020.11.28.401877 — genomics — Posted on 2021-02-01
4237 A pragmatic approach to make theoretical syntheses in ecology
Travassos-Britto, B.; Pardini, R.; El-Hani, C.; Prado, P. I.
10.1101/344200 — ecology — Posted on 2021-02-01
4238 Isolating and Cryo-Preserving Pig Skin Cells for Single Cell RNA Sequencing Study
Han, L.; Jara, C. P.; Wang, O.; Thibivilliers, S.; Woycicki, R. K.; Carlson, M. A.; Velander, W. H.; Araujo, E. P.; Libault, M.; Zhang, C.; Lei, Y.
10.1101/2021.01.31.429035 — cell biology — Posted on 2021-02-01
4241 Half-life of biodegradable plastics in the marine environment depends on material, habitat, and climate zone
Lott, C.; Eich, A.; Makarow, D.; Unger, B.; van Eekert, M.; Schuman, E.; Segre Reinach, M.; Lasut, M. T.; Weber, M.
10.1101/2021.01.31.429013 — microbiology — Posted on 2021-02-01
4243 Diet-regulated production of PDGFcc by macrophages controls energy storage
Cox, N.; Crozet, L.; Holtman, I. R.; Loyher, P.-L.; Lazarov, T.; Mass, E.; Stanley, R.; Glass, C. K.; Geissmann, F.
10.1101/2020.06.15.152397 — immunology — Posted on 2021-02-01
4244 The Drosophila Baramicin polypeptide gene protects against fungal infection
Hanson, M. A.; Cohen, L. B.; Marra, A.; Iatsenko, I.; Wasserman, S. A.; Lemaitre, B.
10.1101/2020.11.23.394148 — immunology — Posted on 2021-02-01
4245 Neuronal morphology and physiology, functional brain networks and memory in temporal lobe epilepsy
Douw, L.; Nissen, I. A.; Fitzsimmons, S. M.; Hillebrand, A.; van Straaten, E. C.; Stam, C. J.; de Witt Hamer, P. C.; Baayen, J. C.; Klein, M.; Reijneveld, J. C.; Heyer, D. B.; Verhoog, M. B.; Wilbers, R.; Hunt, S.; Mansvelder, H. D.; Geurts, J. J.; de Kock, C. P.; Goriounova, N. A.
10.1101/2021.01.31.428369 — neuroscience — Posted on 2021-02-01
4246 A neuroendocrine pathway modulating osmotic stress in Drosophila
Zandawala, M.; Nguyen, T.; Segura, M. B.; Johard, H.; Amcoff, M.; Wegener, C.; Paluzzi, J.-P.; Nassel, D. R.
10.1101/522441 — neuroscience — Posted on 2021-02-01
4250 Chemogenetic activation of nigrostriatal dopamine neurons in freely moving common marmosets
Mimura, K.; Nagai, Y.; Inoue, K.-i.; Matsumoto, J.; Hori, Y.; Sato, C.; Takada, M.; Suhara, T.; Higuchi, M.; Minamimoto, T.
10.1101/2021.01.29.428749 — neuroscience — Posted on 2021-02-01
4252 Visualization and Analysis of Whole Depot Adipose Tissue Neural Innervation
Willows, J. W.; Blaszkiewicz, M.; Lamore, A.; Borer, S.; Dubois, A. L.; Garner, E.; Breeding, W. P.; Tilbury, K. B.; Khalil, A.; Townsend, K. L.
10.1101/788885 — neuroscience — Posted on 2021-02-01
4253 Characterization of cognitive-motor function in women who have experienced intimate partner violence-related brain injury
Maldonado-Rodriguez, N.; Val Crocker, C.; Taylor, E.; Jones, K. E.; Rothlander, K.; Smirl, J.; Wallace, C.; van Donkelaar, P.
10.1101/2021.01.29.428699 — neuroscience — Posted on 2021-02-01
4254 The retrosplenial cortex combines internal and external cues to encode head velocity during navigation
Keshavarzi, S.; Bracey, E. F.; Faville, R. A.; Campagner, D.; Tyson, A. L.; Lenzi, S. C.; Branco, T.; Margrie, T. W.
10.1101/2021.01.22.427789 — neuroscience — Posted on 2021-02-01
4256 FGF21 Normalizes Plasma Glucose in Mouse Models of Type 1 Diabetes and Insulin Receptor Dysfunction
Diener, J. L.; Mowbray, S.; Yowe, D.; Xu, J.; Caplan, S.; Misra, A.; Kapur, A.; Huang, W.-J.; Shapiro, J.; Ke, X.; Wu, X.; Bose, A.; Panza, D.; Chen, M.; Beaulieu, V.; Gao, J.
10.1101/2021.01.04.425295 — pharmacology and toxicology — Posted on 2021-02-01
4257 FGFR2 fusion proteins drive oncogenic transformation of mouse liver organoids towards cholangiocarcinoma
Cristinziano, G.; Porru, M.; Lamberti, D.; Buglioni, S.; Rollo, F.; Amoreo, C. A.; Manni, I.; Giannarelli, D.; Cristofoletti, C.; Russo, G.; Borad, M. J.; Grazi, G. L.; Diodoro, M. G.; Giordano, S.; Sacconi, A.; Forcato, M.; Anastasi, S.; Leonetti, C.; Segatto, O.
10.1101/2020.05.20.106104 — cancer biology — Posted on 2021-02-01
4261 Geographic heterogeneity impacts drug resistance predictions in Mycobacterium tuberculosis
Gan, G. L.; Nguyen, M.; Willie, E.; Rezaie, M.; Lee, B.; Chauve, C.; Libbrecht, M.; Chindelevitch, L.
10.1101/2020.09.17.301226 — bioinformatics — Posted on 2021-02-01
4262 Network science inspires novel tree shape statistics
Chindelevitch, L.; Hayati, M.; Poon, A.; Colijn, C.
10.1101/608646 — bioinformatics — Posted on 2021-02-01
4263 Evolving cryo-EM structural approaches for GPCR drug discovery
Zhang, X.; Johnson, R. M.; Drulyte, I.; Yu, L.; Kotecha, A.; Danev, R.; Wootten, D.; Sexton, P. M.; Belousoff, M. J.
10.1101/2021.01.11.426276 — biochemistry — Posted on 2021-02-01
4264 SCOPE: Flexible targeting and stringent CARF activation enables type III CRISPR-Cas diagnostics
Steens, J. A.; Zhu, Y.; Taylor, D. W.; Bravo, J. P. K.; Prinsen, S. H. P.; Schoen, C. D.; Keijser, B. J. F.; Ossendrijver, M.; Hofstra, L. M.; Brouns, S. J. J.; Shinkai, A.; van der Oost, J.; Staals, R. H. J.
10.1101/2021.02.01.429135 — biochemistry — Posted on 2021-02-01
4266 Metabolic differentiation of co-occurring Accumulibacter clades revealed through genome-resolved metatranscriptomics
McDaniel, E. A.; Moya-Flores, F.; Keene Beach, N.; Camejo, P. Y.; Oyserman, B. O.; Kizaric, M.; Khor, E. H.; Noguera, D. R.; McMahon, K. D.
10.1101/2020.11.23.394700 — genomics — Posted on 2021-02-01
4267 Non-essential ribosomal proteins in bacteria and archaea identified using COGs
Galperin, M. Y.; Wolf, Y. I.; Garushyants, S. K.; Vera Alvarez, R.; Koonin, E. V.
10.1101/2021.01.31.429008 — genomics — Posted on 2021-02-01
4270 Common breast cancer risk loci predispose to distinct tumor subtypes
Ahearn, T. U.; Zhang, H.; Michailidou, K.; Milne, R. L.; Bolla, M. K.; Dennis, J.; Dunning, A. M.; Lush, M.; Wang, Q.; Andrulis, I. L.; Anton-Culver, H.; Arndt, V.; Aronson, K. J.; Auer, P. L.; Augustinsson, A.; Baten, A.; Becher, H.; Behrens, S.; Benitez, J.; Bermisheva, M.; Blomqvist, C.; Bojesen, S. E.; Bonanni, B.; Borresen-Dale, A.-L.; Brauch, H.; Brenner, H.; Brooks-Wilson, A.; Bruning, T.; Burwinkel, B.; Canzian, F.; Castelao, J. E.; Chang-Claude, J.; Chanock, S.; Chenevix-Trench, G.; Clarke, C. L.; NBCS Collaborators, ; Collee, J. M.; Cox, A.; Cross, S. S.; Czene, K.; Daly, M. B.; Dev
10.1101/733402 — genetics — Posted on 2021-02-01
4271 Independent origins of the Golgi phosphoprotein 3 oncoprotein gene
Opazo, J. C.; Vandewege, M. W.; Gutierrez, J.; Zavala, K.; Vargas-Chacoff, L.; Morera, F. J.; Mardones, G. A.
10.1101/2021.01.31.429031 — evolutionary biology — Posted on 2021-02-01
4273 Mitochondrial energy dysfunction induces remodeling of the cardiac mitochondrial protein acylome
Peoples, J. N.; Ghazal, N.; Duong, D. M.; Hardin, K. R.; Seyfried, N. T.; Faundez, V.; Kwong, J. Q.
10.1101/2021.01.31.429057 — cell biology — Posted on 2021-02-01
4275 CSF metabolites associate with CSF tau and improve prediction of Alzheimer's disease status
Dong, R.; Darst, B. F.; Deming, Y.; Ma, Y.; Lu, Q.; Zetterberg, H.; Blennow, K.; Carlsson, C. M.; Johnson, S. C.; Asthana, S.; Engelman, C. D.
10.1101/2021.01.31.429054 — molecular biology — Posted on 2021-02-01
4276 Genome-scale metabolic modelling of P. thermoglucosidasius NCIMB 11955 reveals metabolic bottlenecks in anaerobic metabolism.
Mol, V.; Bennett, M.; Sanchez, B. J.; Lisowska, B. K.; Herrgard, M. J.; Toftgaard Nielsen, A.; Leak, D. J.; Sonnenschein, N.
10.1101/2021.02.01.429138 — microbiology — Posted on 2021-02-01
4279 Induction of selective cell death in HIV-1-infected cells by DDX3 inhibitors leads to depletion of the inducible reservoir
Rao, S.; Lungu, C.; Crespo, R.; Steijaert, T. H.; Gorska, A.; Palstra, R.-J.; Prins, H. A. B.; van Ijcken, W.; Rokx, C.; Mueller, Y. M.; Van Kampen, J. J. A.; Verbon, A.; Katsikis, P. D.; Boucher, C. A. B.; Gruters, R. A.; Mahmoudi, T.
10.1101/2020.08.26.266726 — microbiology — Posted on 2021-02-01
4280 Enhanced immunogenicity of a synthetic DNA vaccine expressing consensus SARS-CoV-2 Spike protein using needle-free immunization
Alamri, S. S.; Alluhaybi, K. A.; Alhabbab, R. Y.; Algaissi, A.; Almahboub, S.; Alfaleh, M. A.; Abujamel, T. S.; Abdulaal, W.; ElAssouli, M.-Z.; Alharbi, R.; Hassanain, M.; Hashem, A. M.
10.1101/2021.02.01.429219 — immunology — Posted on 2021-02-01
4281 Novel EGFRvIII-CAR transgenic mice for rigorous preclinical studies in syngeneic mice
Chuntova, P.; Hou, Y.; Naka, R.; Goretsky, Y.; Nejo, T.; Kohanbash, G.; Chen, T.; Mende, A. L.; Montoya, M.; Yamamichi, A.; Downey, K. M.; Diebold, D.; Skinner, J.; Liang, H.-E.; Schwer, B.; Okada, H.
10.1101/2021.01.31.429020 — immunology — Posted on 2021-02-01
4284 Outer Hair Cell Function is Normal in βV Spectrin Knockout Mice
Stankewich, M. C.; Bai, J.-P.; Stabach, P. R.; Khan, S.; Song, L.; Morrow, J. S.; Santos-Sacchi, J.; Navaratnam, D. S.
10.1101/2021.02.01.427491 — neuroscience — Posted on 2021-02-01
4285 Nanotraps for the containment and clearance of SARS-CoV-2
Chen, M.; Rosenberg, J.; Cai, X.; Lee, A. C. H.; Shi, J.; Nguyen, M.; Wignakumar, T.; Mirle, V.; Edobor, A. J.; Fung, J.; Donington, J. S.; Shanmugarajah, K.; Chang, E. B.; Randall, G.; Penaloza-MacMaster, P.; Tian, B.; Madariaga, M. L.; Huang, J.
10.1101/2021.02.01.428871 — bioengineering — Posted on 2021-02-01
4287 Drosophila Evolution over Space and Time (DEST) - A New Population Genomics Resource
Kapun, M.; Nunez, J. C. B.; Bogaerts-Marquez, M.; Murga-Moreno, J.; Paris, M.; Outten, J.; Coronado-Zamora, M.; Tern, C.; Rota-Stabelli, O.; Garcia Guerreiro, M. P. P.; Casillas, S.; Orengo, D. J.; Puerma, E.; Kankare, M.; Ometto, L.; Loeschcke, V. V.; Onder, B. S.; Abbott, J. K.; Schaeffer, S. W.; Rajpurohit, S.; Behrman, E. L.; Schou, M. F.; Merritt, T. J. S.; Lazzaro, B. P. B.; Glaser-Schmitt, A.; Argyridou, E.; Staubach, F.; Wang, Y.; Tauber, E.; Serga, S. V.; Fabian, D. K.; Dyer, K. A.; Wheat, C. W.; Parsch, J.; Grath, S.; Savic Veselinovic, M.; Stamenkovic-Radak, M.; Jelic, M.; Buendia-R
10.1101/2021.02.01.428994 — genomics — Posted on 2021-02-01
4289 REFINING THE IDENTITY AND ROLE OF KV4 CHANNELS IN MOUSE SUBSTANTIA NIGRA DOPAMINERGIC NEURONS
Haddjeri-Hopkins, A.; Tapia, M.; Ramirez-Franco, J.; Tell, F.; Marqueze-Pouey, B.; Amalric, M.; Goaillard, J.-M.
10.1101/2021.02.01.429100 — neuroscience — Posted on 2021-02-01
4291 Identification of a conserved neutralizing epitope present on spike proteins from highly pathogenic coronaviruses
Huang, Y.; Nguyen, A. W.; Hsieh, C.-L.; Silva, R.; Olaluwoye, O. S.; Wilen, R.; Kaoud, T. S.; Azouz, L. R.; Qerqez, A. N.; Le, K. C.; Bohanon, a. L.; DiVenere, A. M.; Liu, Y.; Amengor, D.; Dalby, K.; D'Arcy, S.; McLellan, J. S.; Maynard, J. A.
10.1101/2021.01.31.428824 — biochemistry — Posted on 2021-02-01
4292 Unraveling the interaction between doxorubicin and DNA origami nanostructures for customizable chemotherapeutic drug release
Ijäs, H.; Shen, B.; Heuer-Jungemann, A.; Keller, A.; Kostiainen, M. A.; Liedl, T.; Ihalainen, J. A.; Linko, V.
10.1101/2020.05.13.088054 — biochemistry — Posted on 2021-02-01
4295 Nelfinavir markedly improves lung pathology in SARS-CoV-2-infected Syrian hamsters despite a lack of an antiviral effect
Foo, C. S.; Abdelnabi, R.; Kaptein, S. J. F.; Zhang, X.; ter Horst, S.; Mols, R.; Delang, L.; Rocha-Pereira, J.; Coelmont, L.; Leyssen, P.; Dallmeier, K.; Vergote, V.; Heylen, E.; Vangeel, L.; Chatterjee, A. K.; Annaert, P.; Augustijns, P.; De Jonghe, S.; Jochmans, D.; Weynand, B.; Neyts, J.
10.1101/2021.02.01.429108 — microbiology — Posted on 2021-02-01
4296 Sequential delivery of LAIV and SARS-CoV-2 in the ferret model can reduce SARS-CoV-2 shedding and does not result in enhanced lung pathology.
Ryan, K. A.; Schewe, K. E.; Crowe, J.; Fotheringham, S. A.; Hall, Y.; Humphreys, R.; Marriott, A. C.; Paterson, J.; Rayner, E.; Salguero, F. J.; Watson, R. J.; Whittaker, C. J.; Carroll, M. W.; Dibben, O.
10.1101/2021.02.01.429110 — microbiology — Posted on 2021-02-01
4297 Identification of anti-severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) oxysterol derivatives in vitro
Ohashi, H.; Wang, F.; Stappenbeck, F.; Tsuchimoto, K.; Kobayashi, C.; Saso, W.; Kataoka, M.; Kuramochi, K.; Muramatsu, M.; Suzuki, T.; Sureau, C.; Takeda, M.; Wakita, T.; Parhami, F.; Watashi, K.
10.1101/2021.01.31.429001 — microbiology — Posted on 2021-02-01
4298 Mn2+ coordinates Cap-0-RNA to align substrates for efficient 2'-O-methyl transfer by SARS-CoV-2 nsp16
Minasov, G.; Rosas-Lemus, M.; Shuvalova, L.; Inniss, N. L.; Brunzelle, J. S.; Daczkowski, C. M.; Hoover, P.; Mesecar, A. D.; Satchell, K. J.
10.1101/2021.01.31.429023 — microbiology — Posted on 2021-02-01
4300 Discovery of re-purposed drugs that slow SARS-CoV-2 replication in human cells
Pickard, A.; Calverley, B. C.; Chang, J.; Garva, R.; Lu, Y.; Kadler, K. E.
10.1101/2021.01.31.428851 — immunology — Posted on 2021-02-01
4301 TMEM97 increases in synapses and is a potential synaptic Aβ binding partner in human Alzheimer's disease
Colom-Cadena, M.; Tulloch, J.; Jackson, R. J.; Catterson, J. H.; Rose, J.; Davies, C.; Hooley, M.; Anton-Fernandez, A.; Dunnett, S.; Tempelaar, R.; Tzioras, M.; Izzo, N. J.; Catalano, S. M.; Smith, C.; Spires-Jones, T. L.
10.1101/2021.02.01.428238 — neuroscience — Posted on 2021-02-01
4311 Robust, sensitive, and quantitative single-cell proteomics based on ion mobility filtering
Woo, J.; Clair, G. C.; Williams, S. M.; Feng, S.; Moore, R. J.; Chrisler, W. B.; Smith, R. D.; Kelly, R. T.; Pasa-Tolic, L.; Ansong, C.; Zhu, Y.
10.1101/2021.01.30.428333 — systems biology — Posted on 2021-02-01
4313 Evolution of the bread wheat D-subgenome and enriching it with diversity from Aegilops tauschii
Gaurav, K.; Arora, S.; Silva, P.; Sanchez-Martin, J.; Horsnell, R.; Gao, L.; Brar, G. S.; Widrig, V.; Raupp, J.; Singh, N.; Wu, S.; Kale, S. M.; Chinoy, C.; Nicholson, P.; Quiroz-Chavez, J.; Simmonds, J.; Hayta, S.; Smedley, M. A.; Harwood, W.; Pearce, S.; Gilbert, D.; Kangara, N.; Gardener, C.; Forner-Martinez, M.; Liu, J.; Yu, G.; Boden, S.; Pascuccci, A.; Ghosh, S.; Hafeez, A. N.; O'Hara, T.; Waites, J.; Cheema, J.; Steuernagel, B.; Patpour, M.; Justesen, A. F.; Liu, S.; Rudd, J.; Avni, R.; Sharon, A.; Steiner, B.; Kirana, R. P.; Buerstmayr, H.; Mehrabi, A. A.; Nasyrova, F. Y.; Chayut, N.;
10.1101/2021.01.31.428788 — plant biology — Posted on 2021-02-01
4314 Surviving hypothermia by ferritin-mediated iron detoxification
Pekec, T.; Lewandowski, J.; Komur, A. A.; Sobanska, D.; Guo, Y.; Switonska-Kurkowska, K.; Frankowski, M.; Figiel, M.; Ciosk, R.
10.1101/2021.01.30.428937 — physiology — Posted on 2021-02-01
4315 Vasoconstriction in isolated goat aorta does not increase mean aortic pressure
Gangadharan, N.; V, A.; Jebaraj, B.; Zachariah, S. M.; Devasahayam, S.; Saravana Kumar, G.; Subramani, S.
10.1101/2021.01.30.428980 — physiology — Posted on 2021-02-01
4316 MYC controls metastatic heterogeneity in pancreatic cancer
Maddipati, R.; Norgard, R.; Baslan, T.; Rathi, K.; Zhang, A.; Raman, P.; Pitarresi, J.; Wengyn, M.; Yamazoe, T.; Li, J.; Balli, D.; LaRiviere, M.; Folkert, I.; Millstein, I.; Bermeo, J.; Carpenter, E.; Lowe, S.; Iacobuzio-Donahue, C. A.; Notta, F.; Stanger, B.
10.1101/2021.01.30.428641 — cancer biology — Posted on 2021-02-01
4317 Multicellular immune hubs and their organization in MMRd and MMRp colorectal cancer
Pelka, K.; Hofree, M.; Chen, J.; Sarkizova, S.; Pirl, J. D.; Jorgji, V.; Bejnood, A.; Dionne, D.; Ge, W. H.; Xu, K. H.; Chao, S. X.; Zollinger, D. R.; Lieb, D. J.; Reeves, J. W.; Fuhrman, C. A.; Hoang, M. L.; Delorey, T.; Nguyen, L. T.; Waldmann, J. A.; Klapholz, M.; Wakiro, I.; Cohen, O.; Smillie, C. S.; Cuoco, M. S.; Wu, J.; Su, M.-j.; Yeung, J.; Vijaykumar, B.; Magnuson, A. M.; Asinovski, N.; Moll, T.; Goder-Reiser, M. N.; Applebaum, A. S.; Brais, L. K.; DelloStritto, L. K.; Denning, S. L.; Phillips, S. T.; Hill, E. K.; Meehan, J. K.; Frederick, D. T.; Sharova, T.; Kanodia, A.; Todres, E. Z
10.1101/2021.01.30.426796 — cancer biology — Posted on 2021-02-01
4322 AhNGE : A Database for Arachis hypogaea Nodule Developmental Gene Expression
Shaheen, T.; Tembhare, K.; Singh, A.; Raul, B.; Ghosh, A. K.; Torres-Jerez, I.; Clevenger, J.; Udvardi, M.; Scheffler, B.; Ozias-Akins, P.; Bandyopadhyay, K.; Kumar, S.; Sinharoy, S.
10.1101/2021.01.30.428929 — bioinformatics — Posted on 2021-02-01
4327 dSCOPE: a software to detect sequences critical for liquid-liquid phase separation
Li, S.; Yu, K.; Zhang, Q.; Liu, Z.; Liu, J.; Ju, H.-Q.; Zuo, Z.; Li, X.; Wang, Z.; Cheng, H.; Liu, Z.-X.
10.1101/2021.01.30.428971 — bioinformatics — Posted on 2021-02-01
4329 Manipulation of stimulus waveform and frequency permits targeted fiber activation during vagus nerve stimulation in 2 rodent species
Chang, Y.-C.; Ahmed, U.; Jayaprakash, N.; Abbas, A.; Lin, Q.; Mughrabi, I.; Guo, T.; Wu, Y.-C.; Gabalski, A. H.; Daytz, A.; Ashville, J.; Dokos, S.; Al-Abed, Y.; Zanos, S.
10.1101/2021.01.30.428827 — bioengineering — Posted on 2021-02-01
4330 Production of SARS-CoV-2 virus-like particles in insect cells
mi, Y.; Xie, T.; Zhu, B.; tan, J.; Li, X.; Luo, Y.; Li, F.; Niu, H.; Han, J.; Lv, W.; Wang, J.
10.1101/2021.01.30.428979 — bioengineering — Posted on 2021-02-01
4333 Is energetics or competition a stronger driver of male smallmouth bass seasonal reproductive timing?
Laroche, R. A. S.; Weinersmith, K. L.; Angeloni, L.; Baylis, J. R.; Newman, S. P.; Egan, S. P.; Wiegmann, D. D.
10.1101/2021.01.30.428956 — animal behavior and cognition — Posted on 2021-02-01
4336 Small Intestinal Resident Eosinophils Maintain Gut Homeostasis Following Microbial Colonisation
Shah, K.; Ignacio, A.; Bernier-Latmani, J.; Koeller, Y.; Coakley, G.; Moyat, M.; Hamelin, R.; Armand, F.; Wong, N. C.; Remay, H.; Thomson, C. A.; Bukhard, R.; Dufour, A.; Petrova, T. V.; Harris, N. L.; McCoy, K. D.
10.1101/2021.01.30.428930 — immunology — Posted on 2021-02-01
4338 Non cell-autonomous effect of astrocytes on cerebral cavernous malformations
Lopez-Ramirez, M. A. A.; Soliman, S. I.; Hale, P.; Lai, C. C.; Pham, A.; Estrada, E. J.; McCurdy, S.; Girard, R.; Verma, R.; Moore, T.; Lightle, R.; Hobson, N.; Shenkar, R.; Poulsen, O.; Haddad, G. G.; Daneman, R.; Gongol, B.; Sun, H.; Lagarrigue, F.; Awad, I. A.; Ginsberg, M.
10.1101/2021.01.29.428891 — neuroscience — Posted on 2021-02-01
4341 Separated and overlapping neural coding of face and body identity
Foster, C.; Zhao, M.; Bolkart, T.; Black, M. J.; Bartels, A.; Buelthoff, I.
10.1101/2021.01.30.428936 — neuroscience — Posted on 2021-02-01
4347 PATO: Pangenome Analysis Toolkit
Fernandez-de-Bobadilla, M. D.; Talavera-Rodriguez, A.; Chacon, L.; Baquero, F.; Coque, T. M.; Lanza, V. F.
10.1101/2021.01.30.428878 — bioinformatics — Posted on 2021-02-01
4351 Functional and comparative genome analysis reveals clade-specific genome innovations in the killer fungus Candida auris
Narayanan, A.; Vadnala, R. N.; Ganguly, P.; Selvakumar, P.; Rudramurthy, S.; Prasad, R.; Chakrabarti, A.; Siddharthan, R.; Sanyal, K.
10.1101/2021.01.29.428909 — genomics — Posted on 2021-02-01
4356 Defensive freezing and its relation to approach-avoidance decision-making under threat
Klaassen, F. H.; Held, L.; Figner, B.; O'Reilly, J. X.; Klumpers, F.; de Voogd, L. D.; Roelofs, K.
10.1101/2021.01.29.428809 — neuroscience — Posted on 2021-02-01
4357 Chronic nicotine increases midbrain dopamine neuron activity and biases individual strategies towards reduced exploration in a foraging task.
Dongelmans, M.; Durand-de Cuttoli, R.; Nguyen, C.; Come, M.; Durante, E. K.; Lemoine, D.; Britto, R.; Yahia, T. A.; Mondoloni, S.; Didienne, S.; Bousseyrol, E.; Hannesse, B.; Reynolds, L. M.; Torquet, N.; Dalkara, D.; Marti, F.; Mourot, A.; Naude, J.; Faure, P.
10.1101/2021.01.29.428835 — neuroscience — Posted on 2021-02-01
4358 Just-in-time: gaze guidance behavior while action planning and execution in VR
Keshava, A.; Nezami, F. N.; Neumann, H.; Izdebski, K.; Schueler, T.; Koenig, P.
10.1101/2021.01.29.428782 — neuroscience — Posted on 2021-02-01
4359 Multi-Tissue Multi-Compartment models of diffusion MRI
Frigo, M.; Fick, R. H. J.; Zucchelli, M.; Deslauriers-Gauthier, S.; Deriche, R.
10.1101/2021.01.29.428843 — neuroscience — Posted on 2021-02-01
4360 Characterization of cognitive-motor function in women who have experienced intimate partner violence-related brain injury
Maldonado-Rodriguez, N.; Val Crocker, C.; Taylor, E.; Jones, K. E.; Rothlander, K.; Smirl, J.; Wallace, C.; van Donkelaar, P.
10.1101/2021.01.29.428699 — neuroscience — Posted on 2021-02-01
4361 Fat and carbohydrate interact to potentiate food reward in healthy weight but not in overweight or obesity
Perszyk, E. E.; Hutelin, Z.; Trinh, J.; Kanyamibwa, A.; Fromm, S.; Davis, X. S.; Wall, K. M.; Flack, K. D.; DiFeliceantonio, A.; Small, D. M.
10.1101/2021.01.29.428845 — neuroscience — Posted on 2021-02-01
4368 Neptune: An environment for the delivery of genomic medicine
Venner, E.; Yi, V.; Murdock, D. R.; Kalla, S. E.; Wu, T.-J.; Sabo, A.; Li, S.; Meng, Q.; Tian, X.; Murugan, M.; Cohen, M.; Kovar, C.; Wei, W.-Q.; Chung, W.; Weng, C.; Weisner, G.; Jarvik, G.; Muzny, D. M.; Gibbs, R.
10.1101/2021.01.29.428608 — bioinformatics — Posted on 2021-02-01
4369 DeepRank: A deep learning framework for data mining 3D protein-protein interfaces
Renaud, N.; Geng, C.; Georgievska, S.; Ambrosetti, F.; Ridder, L.; Marzella, D. F.; Bonvin, A. M. J. J.; Xue, L. C.
10.1101/2021.01.29.425727 — bioinformatics — Posted on 2021-02-01
4371 Evolutionary genetic integration of behavioural and endocrine components of the stress response
Houslay, T. M.; Earley, R. L.; White, S. J.; Lammers, W.; Grimmer, A. J.; Travers, L.; Johnson, E.; Young, A. J.; Wilson, A. J.
10.1101/770586 — evolutionary biology — Posted on 2021-02-01
4373 The imprinted Zdbf2 gene finely tunes control of feeding and growth in neonates
Glaser, J.; Iranzo, J.; Borensztein, M.; Marinucci, M.; Gualtieri, A.; Jouhanneau, C.; Teissandier, A.; Gaston-Massuet, C.; Bourc'his, D.
10.1101/2021.01.27.428419 — molecular biology — Posted on 2021-02-01
4374 A Mycobacterium tuberculosis effector targets mitochondrion, controls energy metabolism and limits cytochrome c exit.
Martin, M.; deVisch, A.; Barthe, P.; Turapov, O.; Aydogan, T.; Heriaud, L.; Gracy, J.; Mukamolova, G.; Letourneur, F.; Cohen-Gonsaud, M.
10.1101/2021.01.31.428746 — microbiology — Posted on 2021-02-01
4375 Macrophage Scavenger Receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease
Govaere, O.; Petersen, S. K.; Martinez-Lopez, N.; Wouters, J.; Van Haele, M.; Mancina, R. M.; Jamialahmadi, O.; Bilkei-Gorzo, O.; Lassen, P. B.; Darlay, R.; Peltier, J.; M. Palmer, J.; Younes, R.; Tiniakos, D.; Aithal, G. P.; Allison, M.; Vacca, M.; Goransson, M.; J. Drinnan, M.; Yki-Jarvinen, H.; Dufour, J.-F.; Ekstedt, M.; Francque, S.; Petta, S.; Bugianesi, E.; Schattenberg, J. M.; Day, C. P.; Cordell, H. J.; Topal, B.; Clement, K.; Romeo, S.; Ratziu, V.; Roskams, T.; Daly, A. K.; Anstee, Q. M.; Trost, M.; Hartlova, A.
10.1101/2020.02.01.930115 — immunology — Posted on 2021-02-01
4376 Non-parametric modelling of temporal and spatial counts data from RNA-seq experiments
BinTayyash, N.; Georgaka, S.; John, S.; Ahmed, S.; Boukouvalas, A.; Hensman, J.; Rattray, M.
10.1101/2020.07.29.227207 — bioinformatics — Posted on 2021-02-01
4377 HTSlib - C library for reading/writing high-throughput sequencing data
Bonfield, J. K.; Marshall, J.; Danecek, P.; Li, H.; Ohan, V.; Whitwham, A.; Keane, T.; Davies, R. M.
10.1101/2020.12.16.423064 — bioinformatics — Posted on 2021-02-01
4381 NAP-CNB: Bioinformatic pipeline to predict MHC-I-restricted T cell epitopes in mice
Wert-Carvajal, C.; Sanchez-Garcia, R.; Macias, J. R.; Sanz-Pamplona, R.; Mendez Perez, A.; Alemany, R.; Veiga, E.; Sorzano, C. O. S.; Munoz-Barrutia, A.
10.1101/2020.10.05.327015 — bioinformatics — Posted on 2021-02-01
4382 Long-read-sequenced reference genomes of the seven major lineages of enterotoxigenic Escherichia coli (ETEC) circulating in modern time
von Mentzer, A.; Blackwell, G.; Pickard, D.; Boinett, C. J.; Joffre, E.; Page, A. J.; Svennerholm, A.-M.; Dougan, G.; Sjöling, A.
10.1101/2020.07.16.203430 — genomics — Posted on 2021-02-01
4384 The microbial metabolite p-Cresol induces autistic-like behaviors in mice by remodeling the gut microbiota
Bermudez-Martin, P.; Becker, J. J.; Caramello, N.; Fernandez, S. P.; Costa-Campos, R.; Canaguier, J.; Barbosa, S.; Martinez Gili, L.; Myridakis, A.; Dumas, M. E.; Bruneau, A.; Cherbuy, C.; Langella, P.; Callebert, J.; Launay, J.-M.; Chabry, J.; Barik, J.; Le Merrer, J.; Glaichenhaus, N.; Davidovic, L.
10.1101/2020.05.18.101147 — neuroscience — Posted on 2021-02-01
4386 Fast gene set enrichment analysis
Korotkevich, G.; Sukhov, V.; Budin, N.; Shpak, B.; Artyomov, M. N.; Sergushichev, A.
10.1101/060012 — bioinformatics — Posted on 2021-02-01