bioRxiv directory

Qie, L.; Elsy, A.; Stumvoll, A.; Kwasnicka, M.; Peel, A.; Sullivan, J.; Ettinger, M.; Robertson, A.; Brisbane, J.; Sawyer, A.; Lui, Y.; Ow, S.; Sebastianelli, M.; Majcher, B.; Duan, M.; Vigus, H.; Pounsin, G.; Nilus, R.; Ewers, R.

10.1101/406025 — ecology — Posted on 2018-08-31

18 TMEM135 is an LXR-Inducible Regulator of Peroxisomal Metabolism

Renquist, B. J.; Madanayake, T. W.; Ghimire, S.; Geisler, C. E.; Xu, Y.; Bogan, R. L.

10.1101/334979 — cell biology — Posted on 2018-08-31

19 Analysis of a structured intronic region of the LMP2 pre-mRNA from EBV reveals associations with human regulatory proteins.

Moss, W. N.; Kumarasinghe, N.

10.1101/405977 — molecular biology — Posted on 2018-08-31

20 High throughput single cell sequencing of both T-cell-receptor-beta alleles

Hosoya, T.; Li, H.; Ku, C.-J.; Wu, Q.; Guan, Y.; Engel, J. D.

10.1101/320614 — immunology — Posted on 2018-08-31

21 Genetic continuity in the last seven Millennia in human hepatitis B viruses

Lei, X.; Zhang, Y.; Huang, S.

10.1101/404426 — evolutionary biology — Posted on 2018-08-31

22 GenoDup Pipeline: a tool to detect genome duplication using the dS-based method

Mao, Y.; Satoh, N.

10.1101/384388 — bioinformatics — Posted on 2018-08-31

23 ganon: continuously up-to-date with database growth for precise short read classification in metagenomics

Piro, V. C.; Dadi, T. H.; Seiler, E.; Reinert, K.; Renard, B. Y.

10.1101/406017 — bioinformatics — Posted on 2018-08-31

24 Understanding visual attention with RAGNAROC: A Reflexive Attention Gradient through Neural AttRactOr Competition

Wyble, B.; Callahan-Flintoft, C.; Chen, H.; Marinov, T.; Sarkar, A.; Bowman, H.

10.1101/406124 — neuroscience — Posted on 2018-08-31

25 Neural basis of Transcranial Magnetic Stimulation at the single-cell Level

Romero, M. C.; Davare, M.; Armendariz, M.; Janssen, P.

10.1101/405753 — neuroscience — Posted on 2018-08-31

26 Identification of microRNA-27a as a key regulator of cholesterol homeostasis

Khan, A. A.; Gupta, V.; Kalyani, A.; Arige, V.; Reddy, S.; Barthwal, M. K.; Dikshit, M.; Reddy, B.; Mahapatra, N. R.

10.1101/383448 — molecular biology — Posted on 2018-08-31

27 Nanoscale mapping of DNA dynamics reveals activity-driven genome organization in living human cells

Shaban, H. A.; Barth, R.; Bystricky, K.

10.1101/405969 — biophysics — Posted on 2018-08-31

28 Aperture Phase Modulation with Adaptive Optics: A Novel Approach for Speckle Reduction and Structure Extraction in Optical Coherence Tomography

Zhang, P.; Manna, S. K.; Miller, E. B.; Jian, Y.; Meleppat, R. K.; Sarunic, M. V.; Pugh, E. N.; Zawadzki, R. J.

10.1101/406108 — bioengineering — Posted on 2018-08-31

29 The frontal aslant tract (FAT) and its role in speech, language and executive function

Dick, A. S.; Garic, D.; Graziano, P.; Tremblay, P.

10.1101/249912 — neuroscience — Posted on 2018-08-31

30 Neuromagnetic signatures of the spatiotemporal transformation for manual pointing

Blohm, G.; Alikhanian, H.; Gaetz, W.; Goltz, H. C.; DeSouza, J. F.; Cheyne, D. O.; Crawford, J. D.

10.1101/253328 — neuroscience — Posted on 2018-08-31

31 Acute Psychological Stress Triggers Circulating Cell-Free Mitochondrial DNA

Trumpff, C.; Marsland, A. L.; Basualto-Alarcon, C.; Martin, J. L.; Carroll, J. E.; Sturm, G.; Vincent, A. E.; Mosharov, E. V.; Gu, Z.; Kaufman, B. A.; Picard, M.

10.1101/405886 — molecular biology — Posted on 2018-08-31

32 Molecular Characterisation of the Synovial Fluid Microbiome

Hammad, D. B.; Tonge, D. P.

10.1101/405613 — microbiology — Posted on 2018-08-31

33 Ontology of RNA Sequencing (ORNASEQ) and its application

Fisher, S.; Kim, J.

10.1101/405720 — genomics — Posted on 2018-08-31

34 Flexible statistical methods for estimating and testing effects in genomic studies with multiple conditions

Urbut, S. M.; Wang, G.; Carbonetto, P.; Stephens, M.

10.1101/096552 — genomics — Posted on 2018-08-31

35 Allele frequency-free inference of close familial relationships from genotypes or low depth sequencing data

Waples, R. K.; Albrechtsen, A.; Moltke, I.

10.1101/260497 — genetics — Posted on 2018-08-31

36 Divergence in the face of gene flow in two Charadrius plovers along the Chinese coast

Wang, X.; Que, P.; Heckel, G.; Hu, J.; Zhang, X.; Chiang, C.-Y.; Huang, Q.; Liu, S.; Martinez, J.; Zhang, N.; Pagani-Nunez, E.; Dingle, C.; Yan, L. Y.; Szekely, T.; Zhang, Z.; Liu, Y.

10.1101/406041 — evolutionary biology — Posted on 2018-08-31

37 Common practice solvent extraction does not reflect actual emission of a sex pheromone during butterfly courtship

Visser, B.; Dublon, I. A. N.; Heuskin, S.; Laval, F.; Bacquet, P. M. B.; Lognay, G.; Nieberding, C. M.

10.1101/270462 — evolutionary biology — Posted on 2018-08-31

38 Spatial distribution of mammography adherence in a Swiss urban population and its association with socioeconomic status

Sandoval, J. L.; Himsl, R.; Theler, J.-M.; Gaspoz, J.-M.; Joost, S.; Guessous, I.

10.1101/404673 — epidemiology — Posted on 2018-08-31

39 Age Distribution, Trends, and Forecasts of Under-5 Mortality in Sub-Saharan Africa

Mejia-Guevara, I.; Zuo, W.; Bendavid, E.; Li, N.; Tuljapurkar, S. D.

10.1101/405258 — epidemiology — Posted on 2018-08-31

40 Applying optimal control theory to complex epidemiological models to inform real-world disease management

Bussell, E. H.; Dangerfield, C. E.; Gilligan, C. A.; Cunniffe, N. J.

10.1101/405746 — epidemiology — Posted on 2018-08-31

41 On the role of different age groups during pertussis epidemics in California, 2010 and 2014

Mahmud, A.; Lipsitch, M.; Goldstein, E.

10.1101/405076 — epidemiology — Posted on 2018-08-31

42 Sensory neurons control heritable adaptation to stress through germline reprogramming

Giusy, Z.; Kache, V.; Robles, P.; Chaudhuri, J.; Hill, B.; Bateson, C.; Pires da Silva, A.

10.1101/406033 — developmental biology — Posted on 2018-08-31

43 Self-organised segregation of bacterial chromosomal origins

Hofmann, A.; Mäkelä, J.; Sherratt, D.; Heermann, D.; Murray, S. M.

10.1101/304600 — biophysics — Posted on 2018-08-31

44 A New Clustering and Nomenclature for Beta Turns Derived from High-Resolution Protein Structures

Shapovalov, M.; Vucetic, S.; Dunbrack, R. L.

10.1101/390211 — bioinformatics — Posted on 2018-08-31

45 Large-scale analysis of the global transcriptional regulation of bacterial gene expression

Yubero, P.; Poyatos, J. F.

10.1101/405894 — systems biology — Posted on 2018-08-31

46 Optimal motor decision-making through competition with opponents

Ota, K.; Takiyama, K.

10.1101/405878 — neuroscience — Posted on 2018-08-31

47 TF-TWAS: Transcription-factor polymorphism associated with tissue-specific gene expression

Tang, Y.-C.; Gottlieb, A.

10.1101/405936 — genomics — Posted on 2018-08-31

48 Increased frequency of travel may act to decrease the chance of a global pandemic

Thompson, R.; Thompson, C.; Pelerman, O.; Gupta, S.; Obolski, U.

10.1101/404871 — epidemiology — Posted on 2018-08-31

49 A deep learning framework for imputing missing values in genomic data

Qiu, Y. L.; Zheng, H.; Gavaert, O.

10.1101/406066 — bioinformatics — Posted on 2018-08-31

50 Complex cell-state changes revealed by single cell RNA sequencing of 76,149 microglia throughout the mouse lifespan and in the injured brain

Hammond, T. R.; Dufort, C.; Dissing-Olesen, L.; Giera, S.; Young, A.; Wysoker, A.; Walker, A. J.; Segel, M.; Nemesh, J.; Saunders, A.; Macosko, E.; Franklin, R. J.; Piao, X.; McCarroll, S.; Stevens, B.

10.1101/406140 — neuroscience — Posted on 2018-08-31

51 Planar cell polarity pathway and development of the human visual cortex

Shin, J.; Ma, S.; Hofer, E.; Patel, Y.; Roshchupkin, G.; Sousa, A. M.; Jian, X.; Gottesmann, R.; Mosley, T. H.; Fornage, M.; Saba, Y.; Pirpamer, L.; Schmidt, R.; Schmidt, H.; Mazoyer, B.; Carrion-Castillo, A.; Bis, J.; Li, S.; Yang, Q.; Luciano, M.; Karama, S.; Lewis, L.; Bastin, M.; Harris, M. A.; Deary, I.; Wardlaw, J. M.; Scholz, M.; Loeffler, M.; Witte, V.; Beyer, F.; Villringer, A.; Adams, H. H.; Ikrum, M. A.; Kremen, W. S.; Gillespie, N. A.; Sestan, N.; Pausova, Z.; Seshadri, S.; Paus, T.

10.1101/404558 — neuroscience — Posted on 2018-08-31

52 ABCF ATPases involved in protein synthesis, ribosome assembly and antibiotic resistance: structural and functional diversification across the tree of life

Murina, V.; Kasari, M.; Takada, H.; Hinnu, M.; Saha, C. K.; Grimshaw, J. W.; Seki, T.; Reith, M.; Putrins, M.; Tenson, T.; Strahl, H.; Hauryliuk, V.; Atkinson, G.

10.1101/220046 — molecular biology — Posted on 2018-08-31

53 Spatial organization of Clostridium difficile S-layer biogenesis

Oatley, P.; Kirk, J. A.; Jones, S.; Fagan, R. P.

10.1101/405993 — microbiology — Posted on 2018-08-31

54 Freshwater diatoms diversify faster than marine in both planktonic and benthic habitats

Nakov, T.; Beaulieu, J. M.; Alverson, A. J.

10.1101/406165 — evolutionary biology — Posted on 2018-08-31

55 Yes-associated protein (YAP) is required in maintaining normal ovarian follicle development and function

Plewes, M.; Hou, X.; Zhang, P.; Wood, J.; Cupp, A.; Davis, J.

10.1101/406256 — cell biology — Posted on 2018-08-31

56 Hierarchical brain network for face and voice integration of emotion expression

Davies-Thompson, J.; Elli, G. V.; Rezk, M.; Benetti, S.; Van Ackeren, M. J.; Collignon, O.

10.1101/197426 — neuroscience — Posted on 2018-08-31

57 Tauopathy in the APPswe/PS1ΔE9 mouse model of familial Alzheimer’s disease

Metaxas, A.; Thygesen, C.; Kempf, S. J.; Anzalone, M.; Vaitheeswaran, R.; Petersen, S.; Landau, A. M.; Audrain, H.; Teeling, J. L.; Darvesh, S.; Brooks, D. J.; Larsen, M. R.; Finsen, B.

10.1101/405647 — neuroscience — Posted on 2018-08-31

58 Plasticity of the electrical connectome of C. elegans

Bhattacharya, A.; Aghayeva, U.; Berghoff, E.; Hobert, O.

10.1101/406207 — neuroscience — Posted on 2018-08-31

59 ADP heptose, a novel pathogen-associated molecular pattern associated with Helicobacter pylori type 4 secretion

Pfannkuch, L.; Hurwitz, R.; Traulsen, J.; Kosma, P.; Schmid, M.; Meyer, T. F.

10.1101/405951 — microbiology — Posted on 2018-08-31

60 Paternal grandparental exposure to crop failure or surfeit during a childhood slow growth period and epigenetic marks on third generational growth-, glucoregulatory and stress genes

Bygren, L. O.; Muller, P.; Brodin, D.; Kaati, G.; Gustafsson, J.-A.; Kral, J. G.

10.1101/215467 — genomics — Posted on 2018-08-31

61 A screen for targets of the Drosophila pseudokinase Tribbles identifies Neuralized and Mindbomb, ubiquitin ligases that mediate Notch signaling

Dobens, L.; Shipman, A.; Nauman, C.; Haymans, B.; Silverstein, R.

10.1101/406249 — developmental biology — Posted on 2018-08-31

62 Probing the evolutionary robustness of two repurposed drugs targeting iron uptake in Pseudomonas aeruginosa

Rezzoagli, C.; Wilson, D.; Weigert, M.; Wyder, S.; Kuemmerli, R.

10.1101/195974 — microbiology — Posted on 2018-08-31

63 Shelterin and subtelomeric DNA sequences control nucleosome maintenance and genome stability

van Emden, T. S.; Forn, M.; Forne, I.; Sarkadi, Z.; Capella, M.; Martin Caballero, L.; Fischer-Burkart, S.; Broenner, C.; Simonetta, M.; Toczyski, D.; Halic, M.; Imhof, A.; Braun, S.

10.1101/405712 — genomics — Posted on 2018-08-31

64 Genome-wide Expression Profiling and Pathway Analysis in Cyclic Stretched Human Trabecular Meshwork Cells

Drewry, M. D.; Cai, J.; Helwa, I.; Hu, E.; Liu, S. C.; Mu, H.; Hu, Y.; Johnson, W. M.; Gonzalez, P.; Stamer, W. D.; Liu, Y.

10.1101/406082 — genomics — Posted on 2018-08-31

65 Identification of subject-specific immunoglobulin alleles from expressed repertoire sequencing data

Gadala-Maria, D.; Gidoni, M.; Marquez, S.; Vanderheiden, J. A.; Kos, J. T.; Watson, C.; O'Connor, K. C.; Yaari, G.; Kleinstein, S. H.

10.1101/405704 — bioinformatics — Posted on 2018-08-31

66 A bipartite boundary element restricts UBE3A imprinting to mature neurons.

Hsiao, J. S.; Germain, N. D.; Wilderman, A.; Stoddard, C.; Wojenski, L. A.; Villafano, G. J.; Core, L.; Cotney, J.; Chamberlain, S. J.

10.1101/404061 — genetics — Posted on 2018-08-31

67 Anti-microRNA screen uncovers miR-17 family within miR-17~92 cluster as the primary driver of kidney cyst growth

Yheskel, M.; Lakhia, R.; Flaten, A.; Patel, V.

10.1101/405100 — genetics — Posted on 2018-08-31

68 Nanoscale mapping of DNA dynamics reveals activity-driven genome organization in living human cells

Shaban, H. A.; Barth, R.; Bystricky, K.

10.1101/405969 — biophysics — Posted on 2018-08-31

69 The evolution of infanticide by females in mammals

Lukas, D.; Huchard, E.

10.1101/405688 — animal behavior and cognition — Posted on 2018-08-31

70 Mutant Screen Reveals the Piccolo’s Control over Depression and Brain-Gonad Crosstalk

A. Medrano, G.; Singh, M.; J. Plautz, E.; B. Good, L.; M. Chapman, K.; Chaudhary, J.; Jaichander, P.; M. Powell, H.; Pudasaini, A.; M. Shelton, J.; A. Richardson, J.; Xie, X.-J.; Ivics, Z.; Braun, C.; Ackermann, F.; C. Garner, C.; Izsvak, Z.; Hamra, F. K.

10.1101/405985 — genetics — Posted on 2018-08-31

71 Is Actin Filament and Microtubule Growth Reaction- or Diffusion-Limited?

Pausch, J.; Pruessner, G.

10.1101/406090 — biophysics — Posted on 2018-08-31

72 Structural basis of integrin α6β4 interaction with the bullous pemphigoid antigen BP230 in hemidesmosomes

Manso, J. A.; Gomez-Hernandez, M.; Carabias, A.; Alonso-Garcia, N.; Garcia-Rubio, I.; Kreft, M.; Sonnenberg, A.; de Pereda, J. M.

10.1101/402123 — biophysics — Posted on 2018-08-31

73 Introduction of Kinesin-13 family specific residues increases the microtubule end residence time of a Kinesin-1

Belsham, H. R.; Friel, C. T.

10.1101/405654 — biochemistry — Posted on 2018-08-31

74 CDK inhibitors reduce cell proliferation and reverse hypoxia-induced metastasis of neuroblastoma tumours in a chick embryo model

Swadi, R. R.; Sampat, K.; Herrmann, A.; Losty, P. D.; See, V.; Moss, D.

10.1101/405639 — cancer biology — Posted on 2018-08-31

75 Quantifying Molecular Forces with Serially Connected Force Sensors

Murad, Y.; Li, I. T. S.

10.1101/405761 — biophysics — Posted on 2018-08-31

76 Genetic control of the HDL proteome

Pamir, N.; Pan, C.; Plubell, D. L.; Hutchins, P. M.; Tang, C.; Wimberger, J.; Irwin, A.; Vallim, T. Q. d. A.; Heinecke, J. W.; Lusis, A. J.

10.1101/405811 — systems biology — Posted on 2018-08-31

77 Aggregation of Vibrio cholerae by cationic polymers enhances quorum sensing but over-rides biofilm dissipation in response to autoinduction

Perez-Soto, N.; Creese, O.; Fernandez-Trillo, F.; Krachler, A.-M.

10.1101/333823 — microbiology — Posted on 2018-08-31

78 Transcription activity contributes to the firing of non-constitutive origins in Trypanosoma brucei

da Silva, M. S.; Cayres-Silva, G. R.; Vitarelli, M. O.; Marin, P. A.; Hiraiwa, P. M.; Araujo, C. B.; Avila, A. R.; Reis, M. S.; Elias, M. C.

10.1101/398016 — molecular biology — Posted on 2018-08-31

79 Versatile genome editing with the prototypical Streptococcus thermophilus CRISPR1-Cas9 system

Carter, S.; Agudelo, D.; Duringer, A.; Loehr, J.; Mouchiroud, M.; Cyr, D.; Waters, P. J.; Laplante, M.; Doyon, Y.

10.1101/321208 — molecular biology — Posted on 2018-08-31

80 High-throughput mapping of long-range neuronal projection using in situ sequencing

Chen, X.; Kebschull, J. M.; Zhan, H.; Sun, Y.-C.; Zador, A. M.

10.1101/294637 — neuroscience — Posted on 2018-08-31

81 A common genomic code for chromatin architecture and recombination landscape

Jabbari, K.; Wirtz, J.; Rauscher, M.; Wiehe, T.

10.1101/293837 — genomics — Posted on 2018-08-31

82 Sleep timing in industrial and pre-industrial societies syncs to the light/dark cycle

Martin-Olalla, J. M.

10.1101/392035 — physiology — Posted on 2018-08-31

83 The N-end Rule Pathway and Ubr1 enforce the compartmentalization of mitochodrial and secretory proteins through the recognition of P2-encoded cellular location signals

Tran, A.

10.1101/392373 — cell biology — Posted on 2018-08-31

84 Heterochrony of puberty in the European Badger (Meles meles) can be explained by growth rate and group-size: Evidence for two endocrinological phenotypes

Sugianto, N. A.; Newman, C.; Macdonald, D. W.; Buesching, C. D.

10.1101/405803 — zoology — Posted on 2018-08-31

85 Soma-axon coupling configurations that enhance neuronal coincidence detection

Goldwyn, J. H.; Remme, M.; Rinzel, J.

10.1101/405829 — neuroscience — Posted on 2018-08-31

86 Eye-position error influence over \"open-loop\" smooth pursuit initiation

Buonocore, A.; Skinner, J.; Hafed, Z. M.

10.1101/404491 — neuroscience — Posted on 2018-08-31

87 Comparative genomics and divergence time estimation of the anaerobic fungi in herbivorous mammals

Wang, Y.; Youssef, N.; Couger, M.; Hanafy, R.; Elshahed, M.; Stajich, J. E.

10.1101/401869 — evolutionary biology — Posted on 2018-08-31

88 Pseudomonas aeruginosa PA5oct jumbo phage reduces planktonic and biofilm population and impacts its host virulence through a pseudolysogeny event

Olszak, T.; Danis-Wlodarczyk, K.; Arabski, M.; Gula, G.; Wasik, S.; Higgins, G.; Harvey, B. J.; Lavigne, R.; Drulis-Kawa, Z.

10.1101/405027 — microbiology — Posted on 2018-08-31

89 Elevated pyrimidine dimer formation at distinct genomic bases underlie promoter mutation hotspots in UV-exposed cancers

Elliott, K.; Bostrom, M.; Filges, S.; Lindberg, M.; Van den Eynden, J.; Stahlberg, A.; Clausen, A. R.; Larsson, E.

10.1101/404434 — cancer biology — Posted on 2018-08-31

90 The capsule regulatory network of Klebsiella pneumoniae defined by density-TraDISort

Dorman, M. J.; Feltwell, T.; Goulding, D.; Parkhill, J.; Short, F. L.

10.1101/404400 — microbiology — Posted on 2018-08-31

91 Chiral DNA sequences as commutable reference standards for clinical genomics

Deveson, I. W.; Madala, B. S.; Blackburn, J.; Barker, C.; Wong, T.; Barton, K. M.; Smith, M. A.; Watkins, N. D.; Mercer, T. R.

10.1101/404285 — genomics — Posted on 2018-08-31

92 Effect of cadmium accumulation on the performance of plants and of herbivores that cope differently with organic defences

Godinho, D. P.; Serrano, H. C.; Silva, A.; Branquinho, C.; Magalhaes, S.

10.1101/403576 — ecology — Posted on 2018-08-31

93 Genotype-Phenotype Relations of the von Hippel-Lindau Tumor Suppressor Inferred from a Large-Scale Analysis of Disease Mutations and Interactors

Minervini, G.; Quaglia, F.; Tabaro, F.; Tosatto, S. C. E.

10.1101/405845 — cancer biology — Posted on 2018-08-31

94 Biotransformation of 2,4-dinitrotoluene in a phototrophic co-culture of engineered Synechococcus elongatus and Pseudomonas putida

Fedeson, D. T.; Saake, P.; Calero, P.; Nikel, P. I.; Ducat, D. C.

10.1101/404988 — synthetic biology — Posted on 2018-08-31

95 A Tale of Two Positivities (and the N400): Distinct neural signatures are evoked by confirmed and violated predictions at different levels of representation

Kuperberg, G.; Wlotko, E.

10.1101/404780 — neuroscience — Posted on 2018-08-31

96 Genomic analysis for heavy metal resistance in S. maltophilia

Yu, W.; Chen, X.; Sheng, Y.

10.1101/404954 — microbiology — Posted on 2018-08-31

97 Cryogenically preserved RBCs support gametocytogenesis of Plasmodium falciparum in vitro and gametogenesis in mosquitoes.

Pathak, A.; Shiau, J.; Thomas, M.; Murdock, C.

10.1101/405001 — microbiology — Posted on 2018-08-31

98 Validation of the protein kinase PfCLK3 as a multi-stage cross species malarial drug target

Alam, M.; Sanchez-Azqueta, A.; Janha, O.; Flannery, E.; Mahindra, A.; Mapesa, K.; Brancucci, N.; Antonova-Koch, Y.; Crouch, K.; Simwela, N. V.; Akinwale, J.; Mitcheson, D.; Solyakov, L.; Dudek, K.; Jones, C.; Zapatero, C.; Doerig, C.; Nwakanma, D. C.; Vazquez, M.-J.; Colmenarejo, G.; Lafuente, M.-J.; Leon, M. L.; Waters, A. P.; Jamieson, A. G.; Alvaro, L. E.; Marti, M.; Winzeler, E. A.; Gamo, F. J.; Tobin, A.

10.1101/404459 — microbiology — Posted on 2018-08-31

99 Rapid detection of cytochrome cd1-containing nitrite reductase encoding gene nirS with loop-mediated isothermal amplification assay

Qu, K.; Zhang, X.; Yang, Q.; Jiang, X.; Wang, X.; Li, Y.; Zhao, J.; Hao, Z.; Wang, P.

10.1101/404392 — microbiology — Posted on 2018-08-31

100 Human-like NSG mouse glycoproteins sialylation pattern changes the phenotype of human lymphocytes and sensitivity to HIV-1 infection

Dagur, R. S.; Branch Woods, A.; Mathews, S.; Joshi, P. S.; Quadros, R. M.; Harms, D. W.; Cheng, Y.; Miles, S. M.; Pirruccello, S. J.; Gurumurthy, C. B.; Gorantla, S.; Poluektova, L. Y.

10.1101/404905 — immunology — Posted on 2018-08-31

101 Cross-cancer pleiotropic associations with lung cancer risk in African Americans

Jones, C. C.; Bradford, Y.; Amos, C. I.; Blot, W. J.; Chanock, S. J.; Harris, C. C.; Schwartz, A. G.; Spitz, M. R.; Wiencke, J. K.; Wrensch, M. R.; Wu, X.; Aldrich, M. C.

10.1101/405035 — genetics — Posted on 2018-08-31

102 Adaptive evolution of sperm proteins depends on sperm competition in a pair of Lepidoptera

Mongue, A. J.; Hansen, M. E.; Gu, L.; Sorenson, C. E.; Walters, J. R.

10.1101/404236 — evolutionary biology — Posted on 2018-08-31

103 Extreme variation in rates of evolution in the plastid Clp protease complex

Williams, A. M.; Friso, G.; van Wijk, K. J.; Sloan, D. B.

10.1101/405126 — evolutionary biology — Posted on 2018-08-31

104 Bayesian arrival model for Atlantic salmon smolt counts powered by environmental covariates and expert knowledge

Pulkkinen, H.; Orell, P.; Erkinaro, J.; Mantyniemi, S.

10.1101/399618 — ecology — Posted on 2018-08-31

105 What we (don’t) know about global plant diversity

Cornwell, W. K.; Pearse, W. D.; Dalrymple, R. L.; Zanne, A. E.

10.1101/404376 — ecology — Posted on 2018-08-31

106 Local and regional urbanization: Correlates of parasite community composition and richness in the salt marsh fish, Fundulus heteroclitus

Alfieri, J. M.; Anderson, T. K.

10.1101/404756 — ecology — Posted on 2018-08-31

107 miPIE: NGS-based Prediction of miRNA Using Integrated Evidence

Peace, R. J.; Sheikh Hassani, M.; Green, J. R.

10.1101/405357 — bioinformatics — Posted on 2018-08-31

108 Evaluation of rearing parameters of a self-limiting strain of the Mediterranean fruit fly, Ceratitis capitata (Diptera: Tephritidae)

Elaini, R.; Asadi, R.; Naish, N.; Koukidou, M.; Mazih, A.

10.1101/404749 — zoology — Posted on 2018-08-31

109 A machine learning approach to intensive care discharge.

McWilliams, C.; Lawson, D. J.; Santos-Rodriguez, R.; Gilchrist, I. D.; Champneys, A.; Gould, T. H.; Thomas, M. J. C.; Bourdeaux, C. P.

10.1101/404533 — physiology — Posted on 2018-08-31

110 Looking at the map -- or navigating in a virtual city. Interaction of visuospatial display and spatial strategies in VR

Torok, Z.; Torok, A.

10.1101/405233 — neuroscience — Posted on 2018-08-31

111 Organization of state transitions in the resting-state human cerebral cortex

Kang, J.; Pae, C.; Park, H.-J.

10.1101/404418 — neuroscience — Posted on 2018-08-31

112 Nus Factors Prevent Premature Transcription Termination of Bacterial CRISPR Arrays

Stringer, A. M.; Baniulyte, G.; Lasek-Nesselquist, E.; Wade, J. T.

10.1101/405316 — microbiology — Posted on 2018-08-31

113 rPinecone: Define sub-lineages of a clonal expansion via a phylogenetic tree

Wailan, A. M.; Coll, F.; Heinz, E.; Tonkin-Hill, G.; Corrander, J.; Feasey, N. A.; Thomson, N. R.

10.1101/404624 — genomics — Posted on 2018-08-31

114 Mitotic chromosome binding predicts transcription factor properties in interphase

Raccaud, M.; Alber, A. B.; Friman, E. T.; Agarwal, H.; Deluz, C.; Kuhn, T.; Gebhardt, J. C. M.; Suter, D. M.

10.1101/404723 — genomics — Posted on 2018-08-31

115 Genetic continuity in the last seven Millennia in human hepatitis B viruses

Huang, S.; Lei, X.; Zhang, Y.

10.1101/404426 — evolutionary biology — Posted on 2018-08-31

116 PathoLive - Real time pathogen identification from metagenomic Illumina datasets

Tausch, S. H.; Loka, T. P.; Schulze, J. M.; Andrusch, A.; Klenner, J.; Dabrowski, P. W.; Lindner, M. S.; Nitsche, A.; Renard, B. Y.

10.1101/402370 — bioinformatics — Posted on 2018-08-31

117 Pulvinar influences parietal delay activity and information transmission between dorsal and ventral visual cortex in macaques

Saalmann, Y. B.; Ly, R.; Pinsk, M. A.; Kastner, S.

10.1101/405381 — neuroscience — Posted on 2018-08-31

118 Genome-scale Capture C promoter interaction analysis implicates novel effector genes at GWAS loci for bone mineral density

Chesi, A.; Wagley, Y.; Johnson, M. E.; Manduchi, E.; Su, C.; Lu, S.; Leonard, M. E.; Hodge, K. M.; Pippin, J. A.; Hankenson, K. D.; Wells, A. D.; Grant, S. F. A.

10.1101/405142 — genomics — Posted on 2018-08-31

119 Reduced insulin/IGF-1 signalling in adult parents increases offspring fitness

Lind, M. I.; Ravindran, S.; Sekajova, Z.; Carlsson, H.; Hinas, A.; Maklakov, A. A.

10.1101/405019 — genetics — Posted on 2018-08-31

120 Assessing genomic admixture between cryptic Plutella moth species following secondary contact

Ward, C.; Baxter, S. W.

10.1101/405498 — evolutionary biology — Posted on 2018-08-31

121 Overcoming systematic errors caused by log-transformation of normalized single-cell RNA sequencing data

Lun, A.

10.1101/404962 — bioinformatics — Posted on 2018-08-31

122 Comparing adult hippocampal neurogenesis across species: translating time to predict the tempo in humans

Charvet, C.; Finlay, B.

10.1101/404202 — neuroscience — Posted on 2018-08-31

123 Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus

Monk, I. R.; Shaikh, N.; Begg, S. L.; Gajdiss, M.; Lee, J. Y. H.; Pidot, S. J.; Seemann, T.; Kuiper, M.; Winnen, B.; Hvorup, R.; Collins, B. M.; Bierbaum, G.; Howden, B. P.; McDevitt, C. A.; King, G. F.; Stinear, T. P.

10.1101/405365 — microbiology — Posted on 2018-08-31

124 Discovery of barley gene candidates for low temperature and drought tolerance via environmental association

Lei, L.; Poets, A. M.; Liu, C.; Wyant, S. R.; Hoffman, P. J.; Carter, C. K.; Trantow, R. M.; Shaw, B. G.; Li, X.; Muehlbauer, G.; Katagiri, F.; Morrell, P. L.

10.1101/405399 — genomics — Posted on 2018-08-31

125 ECM deposition is driven by caveolin1-dependent regulation of exosomal biogenesis and cargo sorting

Albacete-Albacete, L.; Navarro-Lerida, I.; Lopez, J. A.; Martin-Padura, I.; Astudillo, A. M.; Van-Der-Heyden, M.; Balsinde, J.; Orend, G.; Vazquez, J.; del Pozo, M. A.

10.1101/405506 — cell biology — Posted on 2018-08-31

126 Icariin induces MC3T3-E1 cell proliferation and differentiation via the BMP-2/Smads/Runx2 signal pathway

An, Q.; Gou, B.; Ma, S.; Goh, E. L.; Liu, G.; Sah, B. K.; Cao, H.; Qing An, Bo Gou, Shaocheng Ma, En Lin Goh, GuoXiong Liu, Bikash Kumar Sah, Hong Cao,

10.1101/405787 — cell biology — Posted on 2018-08-31

127 Inhibition of the Receptor for Advanced Glycation End-Products in Acute Respiratory Distress Syndrome: A Randomised Laboratory Trial in Piglets

Audard, J.; Godet, T.; Blondonnet, R.; Joffredo, J.-B.; Paquette, B.; Belville, C.; Lavergne, M.; Gross, C.; Pasteur, J.; Bouvier, D.; Blanchon, L.; Sapin, V.; Pereira, B.; Constantin, J.-M.; Jabaudon, M.

10.1101/405423 — physiology — Posted on 2018-08-31

128 Hydroxymethylated-P16 Allele Is Transcription-Inactive

Gan, Y.; Li, P.; Han, X.; Qin, S.; Cui, C.; Liu, Z.; Zhou, J.; Gu, L.; Lu, Z.; Zhang, B.; Deng, D.

10.1101/405522 — molecular biology — Posted on 2018-08-31

129 Biogeography and Edaphic Factors Structure Coastal Sediment Microbial Communities More than Vegetation Removal by Sudden Vegetation Dieback

Gorham, C.; Barry, A.; Lawrence, B. A.; Steven, B.

10.1101/405464 — microbiology — Posted on 2018-08-31

130 Alternative oxidase induction protects Candida albicans from respiratory stress and promotes hyphal growth

Duvenage, L.; Walker, L. A.; Bojarczuk, A.; Johnston, S. A.; MacCallum, D. M.; Munro, C. A.; Gourlay, C. W.

10.1101/405670 — microbiology — Posted on 2018-08-31

131 Reproductive functions and genetic architecture of the seminal fluid and sperm proteomes of the mosquito Aedes aegypti

Degner, E. C.; Ahmed-Braimah, Y.; Borziak, K.; Wolfner, M. F.; Harrington, L. C.; Dorus, S.

10.1101/405431 — genomics — Posted on 2018-08-31

132 Body mass index trajectories preceding first report of poor self-rated health: a longitudinal case-control analysis of the English Longitudinal Study of Ageing

Hulman, A.; Ibsen, D. B.; Laursen, A. S. D.; Dahm, C. C.

10.1101/405563 — epidemiology — Posted on 2018-08-31

133 β-actin mRNA interactome mapping by proximity biotinylation

Mukherjee, J.; Hermesh, O.; Nalpas, N.; Franz-Wachtel, M.; Macek, B.; Jansen, R.-P.

10.1101/405589 — cell biology — Posted on 2018-08-31

134 Dogs, but not wolves, lose their sensitivity towards novelty with age

Hansen Wheat, C.; van der Bijl, W.; Temrin, H.

10.1101/405480 — animal behavior and cognition — Posted on 2018-08-31

135 Where the really hard choices are: A general framework to quantify decision difficulty

Franco, J. P.; Yadav, N.; Bossaerts, P.; Murawski, C.

10.1101/405449 — animal behavior and cognition — Posted on 2018-08-31

136 Soil health pilot study in England: outcomes from an on-farm earthworm survey

Stroud, J. L.

10.1101/405795 — scientific communication and education — Posted on 2018-08-31

137 Two key events associated with a transposable element burst occurred during rice domestication

Chen, J.; Lu, L.; Benjamin, J.; Diaz, S.; Hancock, N.; Stajich, J.; Wessler, S.

10.1101/405290 — genomics — Posted on 2018-08-31

138 A sex-stratified genome-wide association study of tuberculosis using a multi-ethnic genotyping array

Schurz, H.; Kinnear, C. J.; Gignoux, C. R.; Wojcik, G. L.; van Helden, P. D.; Tromp, G. C.; Henn, B. M.; Hoal, E. G.; Moller, M.

10.1101/405571 — genetics — Posted on 2018-08-31

139 Structural basis for independent origins of new catalytic machineries in plant AAAD proteins

Torrens-Spence, M. P.; Chiang, Y.-C.; Smith, T.; Vicent, M. A.; Wang, Y.; Weng, J.-K.

10.1101/404970 — biochemistry — Posted on 2018-08-31

140 A tunable dual-input system for on-demand dynamic geneexpression regulation.

Pedone, E.; Lazzarini Rocca, D.; Postiglione, L.; Aulicino, F.; Montes-Olivas, S.; di Bernardo, D.; Cosma, M. P.; Marucci, L.

10.1101/404699 — synthetic biology — Posted on 2018-08-31

141 Single-molecule imaging reveals the interplay between transcription factors, nucleosomes, and transcriptional bursting

Donovan, B. T.; Huynh, A.; Ball, D. A.; Poirier, M. G.; Larson, D. R.; Ferguson, M. L.; Lenstra, T. L.

10.1101/404681 — molecular biology — Posted on 2018-08-31

142 Cerebral Cavernous Malformations Develop through Clonal Expansion of Mutant Endothelial Cells

Detter, M. R.; Snellings, D. A.; Marchuk, D. A.

10.1101/405191 — genetics — Posted on 2018-08-31

143 Systematic characterization of genome editing in primary T cells reveals proximal genomic insertions and enables machine learning prediction of CRISPR-Cas9 DNA repair outcomes

Leenay, R. T.; Aghazadeh, A.; Hiatt, J.; Tse, D.; Hulquist, J.; Krogan, N.; Wu, Z.; Marson, A.; May, A. P.; Zou, J.

10.1101/404947 — cell biology — Posted on 2018-08-31

144 Wnt/Fgf crosstalk is required for the specification of tracheal basal progenitor cells

Hou, Z.; Wu, Q.; Sun, X.; Chen, H.; Li, Y.; Zhang, Y.; Mori, M.; Yang, Y.; Jiang, M.; Que, J.

10.1101/405159 — developmental biology — Posted on 2018-08-31

145 Molecular and evolutionary strategies of meiotic cheating by selfish centromeres

Akera, T.; Trimm, E.; Lampson, M.

10.1101/405068 — cell biology — Posted on 2018-08-31

146 Troponin-I localizes selected apico-basal cell polarity signals

Casas-Tinto, S.; Ferrus, A.

10.1101/404863 — cell biology — Posted on 2018-08-31

147 F-actin dynamics transform filopodial bridges into intercellular nanotubes capable of distant cell communication

Chang, M.; Oh, J.; Doh, J.; Lee, J.-B.

10.1101/405340 — biophysics — Posted on 2018-08-31

148 Crystal Structure of a Natural Light-Gated Anion Channelrhodopsin

Li, H.; Huang, C.-Y.; Govorunova, E.; Schafer, C.; Sineshchekov, O.; Wang, M.; Zheng, L.; Spudich, J.

10.1101/405308 — biochemistry — Posted on 2018-08-31

149 Effects of P16 DNA Methylation on Proliferation, Senescence, and Lifespan of Human Fibroblasts

Gan, Y.; Cui, C.; Xiang, S.; Zhang, B.; Deng, D.

10.1101/405407 — cell biology — Posted on 2018-08-30

150 Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening

Lee, O. W.; Austin, S. M.; Gamma, M. R.; Cheff, D. M.; Lee, T. D.; Wilson, K. M.; Johnson, J. M.; Travers, J. C.; Braisted, J. C.; Guha, R.; Klumpp-Thomas, C.; Shen, M.; Hall, M. D.

10.1101/404665 — cell biology — Posted on 2018-08-30

151 KymoButler: A deep learning software for automated kymograph tracing and analysis

Jakobs, M.; Dimitracopoulos, A.; Franze, K.

10.1101/405183 — cell biology — Posted on 2018-08-30

152 Calcium nanodomains in spindles

Mo, G.; Li, R.; Swider, Z.; Tao, Y.; Mikoshiba, K.; Bement, W.; Liu, J.

10.1101/404715 — cell biology — Posted on 2018-08-30

153 A least microenvironmental uncertainty principle (LEUP) as a generative model of collective cell migration mechanisms.

Barua, A.; Navas Sedeno, J. M.; Hatzikirou, H.

10.1101/404889 — biophysics — Posted on 2018-08-30

154 Neural representations of faces are tuned to eye movements

Stacchi, L.; Ramon, M.; Lao, J.; Caldara, R.

10.1101/402263 — neuroscience — Posted on 2018-08-30

155 Leave-One-Trial-Out (LOTO): A General Approach to Link Single-Trial Parameters of Cognitive Models to Neural Data

Gluth, S.; Meiran, N.

10.1101/403766 — neuroscience — Posted on 2018-08-30

156 Green autofluorescence intensity of skin and fingernails: A novel biomarker for non-invasive evaluation of pathological state of blood vessels

Zhang, M.; Wu, D.; Tao, Y.; Li, Y.; Zhang, S.; Chen, X.; Ying, W.

10.1101/403832 — pathology — Posted on 2018-08-30

157 Chrysalis: A new method for high-throughput histo-cytometry analysis of images and movies.

Kotov, D. I.; Pengo, T.; Mitchell, J. S.; Gastinger, M. J.; Jenkins, M. K.

10.1101/403154 — immunology — Posted on 2018-08-30

158 Potential Bias of Doubly Labeled Water for Measuring Energy Expenditure Differences Between Diets Varying in Carbohydrate

Hall, K. D.; Guo, J.; Chen, K. Y.; Leibel, R. L.; Reitman, M. L.; Rosenbaum, M.; Smith, S. R.; Ravussin, E.

10.1101/403931 — physiology — Posted on 2018-08-30

159 A Public Database on Traumatic Brachial Plexus Injury

Patroclo, C. B.; Ramalho, B. L.; Maia, J.; Rangel, M. L.; Torres, F.; Souza, L.; Braghetto, K. R.; Vargas, C. D.

10.1101/399824 — neuroscience — Posted on 2018-08-30

160 Comparative genomics of ten new Caenorhabditis species

Stevens, L.; Felix, M.-A.; Beltran, T.; Braendle, C.; Caurcel, C.; Fausett, S.; Fitch, D. H.; Frezal, L.; Kaur, T.; Kiontke, K. C.; Newton, M. D.; Noble, L. M.; Richaud, A.; Rockman, M. V.; Sudhaus, W.; Blaxter, M.

10.1101/398446 — evolutionary biology — Posted on 2018-08-30

161 Formation of periodic pigment spots by the reaction-diffusion mechanism

Ding, B.; Patterson, E. L.; Holalu, S.; Li, J.; Johnson, G. A.; Stanley, L. E.; Greenlee, A. B.; Peng, F.; Bradshaw, H. D.; Blackman, B. K.; Yuan, Y.-W.

10.1101/403600 — plant biology — Posted on 2018-08-30

162 Sex-Specific Protection Against Diet-Induced Non-Alcoholic Fatty Liver Disease in TRPV1 Null Mice

Connell, P. J.; Bratz, I. N.; Andrei, S. R.; Eusebio, L.; DelloStritto, D. J.; Fahmy, J. N.; Ferrell, J. M.; Pathak, P.; Chiang, J. Y. L.; Damron, D. S.

10.1101/403881 — physiology — Posted on 2018-08-30

163 Oscillatory infrasonic modulation of the cochlear amplifier by selective attention

Dragicevic, C. D.; Marcenaro, B.; Navarrete, M.; Robles, L.; Delano, P. H.

10.1101/403865 — neuroscience — Posted on 2018-08-30

164 New phylogenomic analysis of the enigmatic phylum Telonemia further resolves the eukaryote tree of life

Strassert, J. F. H.; Jamy, M.; Mylnikov, A. P.; Tikhonenkov, D. V.; Burki, F.

10.1101/403329 — evolutionary biology — Posted on 2018-08-30

165 Sparse network-based regularization for the analysis of patientomics high-dimensional survival data

Verissimo, A.; Carrasquinha, E.; Lopes, M. B.; Oliveira, A. L.; Sagot, M.-F.; Vinga, S.

10.1101/403402 — bioinformatics — Posted on 2018-08-30

166 Total lung capacity without plethysmography

Adam, O.; Cohen, I.; Yip, W.-k.; Shiner, R. J.; Calverley, P.; Peles, Z.; LaPrad, A.; Dagan, Y. J.; Brown, R. J.; Solway, J. J.; Fredberg, J. J.

10.1101/395160 — bioengineering — Posted on 2018-08-30

167 Comprehensive modeling of Spinal Muscular Atrophy in Drosophila melanogaster

Spring, A. M.; Raimer, A. C.; Hamilton, C. D.; Schillinger, M. J.; Matera, A. G.

10.1101/394908 — neuroscience — Posted on 2018-08-30

168 Transcriptome and histone epigenome of Plasmodium vivax salivary-gland sporozoites point to tight regulatory control and potential mechanisms for liver-stage differentiation.

Jex, A.; Mueller, I.; Kappe, S.; Mikolajcjak, S.; Sattabongkot, J.; Patrapuvich, R.; Lindner, S.; Flannery, E.; Koepfli, C.; Ansell, B.; Lerch, A.; Swearingen, K. E.; Emery-Corbin, S. J.; Charnaud, S.; Smith, J.; Merrienne, N.; Moritz, R. L.; Petter, M.; Duffy, M.; Chuenchob, V.

10.1101/145250 — microbiology — Posted on 2018-08-30

169 Potential for microbial anaerobic hydrocarbon degradation in naturally petroleum-associated deep-sea sediments

DONG, X.; Greening, C.; Rattray, J. E.; Chakraborty, A.; Chuvochina, M.; Mayumi, D.; Li, C.; Brooks, J. M.; Bernard, B. B.; Groves, R. A.; Lewis, I. A.; Hubert, C. R. J.

10.1101/400804 — microbiology — Posted on 2018-08-30

170 Re-Evaluating One-step Generation of Mice Carrying Conditional Alleles by CRISPR-Cas9-Mediated Genome Editing Technology

Gurumurthy, C.; Quadros, R.; Adams, J.; Alcaide, P.; Ayabe, S.; Ballard, J.; Batra, S. K.; Beauchampo, M.-C.; Becker, K. A.; Bernas, G.; Brough, D.; Carrillo-Salinas, F.; Dawson, R.; DeMambro, V.; D'Hont, J.; Dibb, K.; Eudy, J. D.; Gan, L.; Gao, J.; Gonzales, A.; Guntur, A.; Guo, H.; Harms, D. W.; Harrington, A.; Hentges, K. E.; Humphreys, N.; Imai, S.; Ishii, H.; Iwama, M.; Jonasch, E.; Karolak, M.; Lakshmanan, I.; Keavney, B.; Khin, N.-C.; Konno, M.; Lawrence, C. B.; Li, L.; Lindner, V.; Liu, X.-D.; Lopez-Castejon, G.; Loudon, A.; Lowe, J.; Jerome-Majeweska, L.; Matsusaka, T.; Miura, H.; Mi

10.1101/393231 — genetics — Posted on 2018-08-30

171 LIONS: Analysis Suite for Detecting and Quantifying Transposable Element Initiated Transcription from RNA-seq

Babaian, A.; Thompson, R.; Lever, J.; Gagnier, L.; Karimi, M. M.; Mager, D. L.

10.1101/149864 — bioinformatics — Posted on 2018-08-30

172 A transgenic pig model expressing a ZsGreen1 reporter across an extensive array of tissues

Desaulniers, A. T.; Cederberg, R. A.; Carreiro, E. P.; Gurumurthy, C. B.; White, B. R.

10.1101/293258 — genomics — Posted on 2018-08-30

173 Sleep regulates visual selective attention in Drosophila

Kirszenblat, L.; Ertekin, D.; Goodsell, J.; Zhou, Y.; Shaw, P.; van Swinderen, B.

10.1101/403246 — animal behavior and cognition — Posted on 2018-08-30

174 Awake fMRI Reveals Brain Regions for Novel Word Detection in Dogs

Prichard, A.; Cook, P. F.; Spivak, M.; Chhibber, R.; Berns, G.

10.1101/178186 — neuroscience — Posted on 2018-08-30

175 Finding the balance between model complexity and performance: Using ventral striatal oscillations to classify feeding behavior in rats

Dwiel, L.; Connerney, M. A.; Green, A. I.; Khokhar, J. Y.; Doucette, W.

10.1101/241919 — neuroscience — Posted on 2018-08-30

176 Arginine to glutamine mutation in olfactomedin-like 3 (OLFML3) is a candidate for severe goniodysgenesis and glaucoma in the Border Collie dog breed.

Pugh, C. A.; Farrell, L. L.; Carlisle, A. J.; Bush, S. J.; Trejo-Reveles, V.; Matika, O.; de Kloet, A.; Walsh, C.; Bishop, S. C.; Prendergast, J. G.; Schoenebeck, J. J.; Rainger, J.; Summers, K. M.

10.1101/321406 — genetics — Posted on 2018-08-30

177 Characterizing animal movement patterns across different scales and habitats using information theory

Owoeye, K. A.; Musolesi, M.; Hailes, S.

10.1101/311241 — ecology — Posted on 2018-08-30

178 Complex associations of environmental factors may explain Blanchard’s Cricket Frog, Acris blanchardi declines and drive population recovery

McCallum, M. L.; Trauth, S. E.

10.1101/272161 — ecology — Posted on 2018-08-30

179 The interaction between ORF18 and ORF30 is required for late gene transcription in Kaposi’s sarcoma-associated herpesvirus

Castaneda, A. F.; Glaunsinger, B. A.

10.1101/401976 — molecular biology — Posted on 2018-08-30

180 Molecular mimicry in deoxy-nucleotide catalysis: the structure of Escherichia coli dGTPase reveals the molecular basis of dGTP selectivity

Barnes, C. O.; Wu, Y.; Song, J.; Lin, G.; Baxter, E. L.; Brewster, A. S.; Nagarajan, V.; Holmes, A.; Soltis, M.; Gronenborn, A.; Ahn, J.; Cohen, A. E.; Calero, G.

10.1101/385401 — biophysics — Posted on 2018-08-30

181 Species-level bacterial community profiling of the healthy sinonasal microbiome using Pacific Biosciences sequencing of full-length 16S rRNA genes

Earl, J. P.; Adappa, N. D.; Krol, J.; Bhat, A. S.; Balashov, S.; Ehrlich, R. L.; Palmer, J. N.; Workman, A. D.; Blasetti, M.; Sen, B.; Hammond, J.; Cohen, N. A.; Ehrlich, G. D.; Mell, J. C.

10.1101/338731 — bioinformatics — Posted on 2018-08-30

182 Parameter tuning is a key part of dimensionality reduction via deep variational autoencoders for single cell RNA transcriptomics

Hu, Q.; Greene, C. S.

10.1101/385534 — bioinformatics — Posted on 2018-08-30

183 Unfold: An integrated toolbox for overlap correction, non-linear modeling, and regression-based EEG analysis

Ehinger, B. V.; Dimigen, O.

10.1101/360156 — neuroscience — Posted on 2018-08-30

184 Cellular and Synaptic Phenotype Compensations Limit Circuit Disruption in Fmr1-KO Mouse Layer 4 Barrel Cortex but Fail to Prevent Deficits in Information Processing

Domanski, A. P.; Booker, S.; Wyllie, D.; Isaac, J.; Kind, P.

10.1101/403725 — neuroscience — Posted on 2018-08-30

185 Wave-like activity patterns in the neuropil of striatal cholinergic interneurons in freely moving mice represent their collective spiking dynamics

Rehani, R.; Atamna, Y.; Tiroshi, L.; Chiu, W.-H.; Aceves Buendia, J. d. J.; Martins, G. J.; Jacobson, G. A.; Goldberg, J. A.

10.1101/404467 — neuroscience — Posted on 2018-08-30

186 Microglial Heterogeneity in a Mouse Model of Alzheimer’s Disease: A Mass Cytometry Analysis

Fountain, E. M.; Esparza, T. J.; Malkova, O.; Oh, S. T.; Brody, D.

10.1101/404178 — neuroscience — Posted on 2018-08-30

187 The Role of Toll-like receptor 4 in respiratory syncytial virus replication, interferon lambda 1 induction, and chemokine responses.

Broadbent, L.; Coey, J. D.; Shields, M. D.; Power, U. F.

10.1101/404384 — microbiology — Posted on 2018-08-30

188 Cell lineage inference from SNP and scRNA-Seq data

Ding, J.; Lin, C.; Bar-Joseph, Z.

10.1101/401943 — genomics — Posted on 2018-08-30

189 Benchmark Problems for Dynamic Modeling of Intracellular Processes

Hass, H.; Loos, C.; Raimundez Alvarez, E.; Timmer, J.; Hasenauer, J.; Kreutz, C.

10.1101/404590 — systems biology — Posted on 2018-08-30

190 Zfp189 Mediates Stress Resilience Through a CREB-Regulated Transcriptional Network in Prefrontal Cortex

Lorsch, Z. S.; Hamilton, P. J.; Ramakrishnan, A.; Parise, E. M.; Wright, W. J.; Salery, M.; Lepack, A.; Mews, P.; Issler, O.; McKenzie, A.; Zhou, X.; Parise, L. F.; Pirpinias, S. T.; Ortiz Torres, I.; Montgomery, S.; Loh, Y.-H. E.; Labonte, B.; Conkey, A.; Symonds, A. E.; Neve, R.; Turecki, G.; Maze, I.; Dong, Y.; Zhang, B.; Shen, L.; Bagot, R. C.; Nestler, E. J.

10.1101/403733 — neuroscience — Posted on 2018-08-30

191 Chromatin architecture reorganisation during neuronal cell differentiation in Drosophila genome

Chathoth, K. T.; Zabet, N. R.

10.1101/395822 — genomics — Posted on 2018-08-30

192 Counterbalancing the time-dependence effect on the human mitochondrial DNA molecular clock

Cabrera, V. M.

10.1101/404582 — evolutionary biology — Posted on 2018-08-30

193 Distinct cross-frequency coupling signatures for top-down and bottom-up information processing in auditory cortex

Marton, C. D.; Fukushima, M.; Camalier, C. R.; Schultz, S. R.; Averbeck, B. B.

10.1101/403980 — neuroscience — Posted on 2018-08-30

194 Origin of gibberellin-dependent transcriptional regulation by molecular exploitation of a transactivation domain in DELLA proteins

Hernandez-Garcia, J.; Briones-Moreno, A.; Dumas, R.; Blazquez, M. A.

10.1101/398883 — evolutionary biology — Posted on 2018-08-30

195 Climate as a driver of adaptive variations in ecological strategies in Arabidopsis thaliana

VASSEUR, F.; Sartori, K.; Baron, E.; Fort, F.; Kazakou, E.; Segrestin, J.; Garnier, E.; Vile, D.; Violle, C.

10.1101/404210 — ecology — Posted on 2018-08-30

196 Spectrum of Neandertal introgression across modern-day humans indicates multiple episodes of human-Neandertal interbreeding

Villanea, F. A.; Schraiber, J.

10.1101/343087 — evolutionary biology — Posted on 2018-08-30

197 Non-linear phenotypic variation uncovers the emergence of heterosis in Arabidopsis thaliana

VASSEUR, F.; Fouqueau, L.; de Vienne, D.; nidelet, t.; Violle, C.; Weigel, D.

10.1101/404616 — evolutionary biology — Posted on 2018-08-30

198 Proteomics-based comparative mapping of the human brown and white adipocyte secretome reveals EPDR1 as a novel batokine

Deshmukh, A. S.; Peijs, L.; Nielsen, S.; Bayarri-Olmos, R.; Larsen, T. J.; Jespersen, N. Z.; Hattel, H.; Holst, B.; Garred, P.; Tang-Christensen, M.; Sanfridson, A.; Gerhart-Hines, Z.; Pedersen, B. K.; Mann, M.; Scheele, C.

10.1101/402867 — physiology — Posted on 2018-08-30

199 The soil microbial food web revisited with metatranscriptomics - predatory Myxobacteria as keystone taxon?

Petters, S.; Soellinger, A.; Bengtsson, M. M.; Urich, T.

10.1101/373365 — microbiology — Posted on 2018-08-30

200 Full Bayesian comparative phylogeography from genomic data

Oaks, J. R.

10.1101/324525 — evolutionary biology — Posted on 2018-08-30

201 Geographic shifts in Aedes aegypti habitat suitability in Ecuador using larval surveillance data and ecological niche modeling: implications of climate change for public health vector control

Lippi, C. A.; Stewart-Ibarra, A. M.; Bajana Loor, M. E. F.; Duenas Zambrano, J. E.; Epinoza Lopez, N. A.; Blackburn, J. K.; Ryan, S. J.

10.1101/404293 — epidemiology — Posted on 2018-08-30

202 Peripartum cardiomyopathy and hypertensive disorders of pregnancy and cardiovascular events among 1.6 million California pregnancies

Arnaout, R.; Nah, G.; Marcus, G.; Tseng, Z. H.; Foster, E.; Harris, I.; Dianji, P.; Klein, L.; Gonzalez, J. M.; Parikh, N. I.

10.1101/404350 — epidemiology — Posted on 2018-08-30

203 TP53 mutations and drug sensitivity in acute myeloid leukaemia cells with acquired MDM2 inhibitor resistance

Michaelis, M.; Schneider, C.; Rothweiler, F.; Rothenburger, T.; Mernberger, M.; Nist, A.; von Deimling, A.; Speidel, D.; Stiewe, T.; Cinatl, J.

10.1101/404475 — pharmacology and toxicology — Posted on 2018-08-30

204 Fast near-whole brain imaging in adult Drosophila during responses to stimuli and behavior

Aimon, S.; Katsuki, T.; Jia, T.; Grosenick, L.; Broxton, M.; Deisseroth, K.; Sejnowski, T. J.; Greenspan, R. J.

10.1101/033803 — neuroscience — Posted on 2018-08-30

205 Animal models with group-specific additive genetic variances: extending genetic group models

Muff, S.; Niskanen, A. K.; Saatoglu, D.; Keller, L. F.; Jensen, H.

10.1101/331157 — evolutionary biology — Posted on 2018-08-30

206 Naked Mole-Rat Cells are Susceptible to Malignant Transformation by SV40LT and Oncogenic Ras

Hadi, F.; Kulaberoglu, Y.; Lazarus, K.; Beattie, P.; Smith, E. S. J.; Khaled, W.

10.1101/404574 — cancer biology — Posted on 2018-08-30

207 The HCP 7T Retinotopy Dataset: Description and pRF Analysis

Benson, N. C.; Jamison, K. W.; Arcaro, M. J.; Vu, A.; Glasser, M. F.; Coalson, T. S.; Van Essen, D. C.; Yacoub, E.; Ugurbil, K.; Winawer, J.; Kay, K.

10.1101/308247 — neuroscience — Posted on 2018-08-30

208 Cell type-dependent control of p53 transcription and enhancer activity by p63

Karsli Uzunbas, G.; Ahmed, F.; Sammons, M. A.

10.1101/268649 — genomics — Posted on 2018-08-30

209 On the variability of Species Abundance Distributions with trophic guild and community structure

Garcia-Callejas, D.

10.1101/289348 — ecology — Posted on 2018-08-30

210 Differential gene expression indicates involvement of F-box proteins and E3 ligases in sexual versus apomictic germline specification in Boechera.

Zuehl, L.; Ibberson, D.; Schmidt, A.

10.1101/403915 — plant biology — Posted on 2018-08-30

211 Methyl-CpG-binding domain 9 (MBD9) is required for H2A.Z incorporation into chromatin at a subset of H2A.Z-enriched regions in the Arabidopsis genome

Sijacic, P.; Holder, D. H.; Bajic, M.; Deal, R. B.

10.1101/404152 — plant biology — Posted on 2018-08-30

212 Binocular disparity can augment the capacity of vision without affecting subjective experience of depth

Railo, H.; Saastamoinen, J.; Kylmala, S.; Peltola, A.

10.1101/222034 — neuroscience — Posted on 2018-08-30

213 Neuronal correlations in MT and MST impair population decoding of opposite directions of random dot motion

Chaplin, T. A.; Hagan, M. A.; Allitt, B. J.; Lui, L. L.

10.1101/267732 — neuroscience — Posted on 2018-08-30

214 Pathogenicity and selective constraint on variation near splice sites

Lord, J.; Gallone, G.; Short, P. J.; McRae, J. F.; Ironfield, H.; Wynn, E. H.; Gerety, S. S.; He, L.; Kerr, B.; Johnson, D. S.; McCann, E.; Kinning, E.; Flinter, F.; Temple, I. K.; Clayton-Smith, J.; McEntagart, M.; Lynch, S. A.; Joss, S.; Douzgou, S.; Dabir, T.; Clowes, V.; McConnell, V. P. M.; Lam, W.; Wright, C. F.; FitzPatrick, D. R.; Firth, H. V.; Barrett, J. C.; Hurles, M. E.; on behalf of the Deciphering Developmental Disorders study,

10.1101/256636 — genetics — Posted on 2018-08-30

215 Trait Heritability in Major Transitions

Herron, M. D.; Zamani-Dahaj, S. A.; Ratcliff, W. C.

10.1101/041830 — evolutionary biology — Posted on 2018-08-30

216 Tenuivirus uses a molecular bridge strategy to overcome insect midgut barriers for virus persistent transmission

Lu, G.; Li, S.; Zhou, C.; Qian, X.; Xiang, Q.; Yang, T.; Wu, J.; Zhou, X.; Zhou, Y.; Ding, X. S.; Tao, X.

10.1101/404657 — pathology — Posted on 2018-08-30

217 DETECTION AND MOLECULAR EPIDEMIOLOGY OF HUMAN BOCAVIRUS IN CHILDREN WITH ACUTE GASTROENTERITIS FROM BRAZIL

Soares, L.; Lima, A. B.; Pantoja, K.; Lobo, P.; Cruz, J.; Bezerra, D.; Bandeira, R.; Guerra, S.; Mascarenhas, J.

10.1101/404632 — microbiology — Posted on 2018-08-30

218 Characterization and mechanism of lead and zinc biosorption by growing Verticillium insectorum J3

Feng, C.-l.; Li, J.; Li, X.; Li, K.-l.; Luo, K.; Liao, X.-s.; Liu, T.

10.1101/404640 — microbiology — Posted on 2018-08-30

219 Bayesian-estimated hierarchical HMMs enable robust analysis of single-molecule kinetic heterogeneity

Hon, J.; Gonzalez, R. L.

10.1101/404327 — biophysics — Posted on 2018-08-30

220 The effects of fixational tremor on the retinal image

Bowers, N. R.; Boehm, A. E.; Roorda, A.

10.1101/403964 — neuroscience — Posted on 2018-08-30

221 The interaction of phylogeny and community structure: linking clades’ ecological structures and trait evolution

Pearse, W. D.; Legendre, P.; Peres Neto, P.; Davies, J.

10.1101/404111 — evolutionary biology — Posted on 2018-08-30

222 Does the strength of women’s attraction to male vocal masculinity track changes in steroid hormones?

Jones, B. C.; Hahn, A.; Pisanski, K.; Wang, H.; Kandrik, M.; Lee, A.; Holzleitner, I. J.; Feinberg, D.; DeBruine, L.

10.1101/403949 — animal behavior and cognition — Posted on 2018-08-30

223 Higher-order discrimination learning by honey bees in a virtual environment

Buatois, A.; Laroche, L.; Avargues-Weber, A.; Giurfa, M.

10.1101/403956 — animal behavior and cognition — Posted on 2018-08-30

224 Study of Oak Ridge soils using BONCAT-FACS-Seq reveals that a large fraction of the soil microbiome is active

Couradeau, E.; Sasse, J.; Goudeau, D.; Nath, N.; Hazen, T. C.; Bowen, B. P.; Malmstrom, R. R.; Northen, T. R.

10.1101/404087 — microbiology — Posted on 2018-08-30

225 Polymer brushes immersed in solvent molecules atthermal equilibrium: A theoretical approach

Farzin, M.

10.1101/404103 — biophysics — Posted on 2018-08-30

226 Exploration of inositol 1,4,5-trisphosphate (IP3) regulated dynamics of N-terminal domain of IP3 receptor reveals early phase molecular events during receptor activation

Chandran, A.; Chee, X.; L. Prole, D.; Rahman, T.

10.1101/404020 — bioinformatics — Posted on 2018-08-29

227 HMP16SData: Efficient Access to the Human Microbiome Project through Bioconductor

Schiffer, L.; Azhar, R.; Shepherd, L.; Ramos, M.; Geistlinger, L.; Huttenhower, C.; Dowd, J. B.; Segata, N.; Waldron, L.

10.1101/299115 — bioinformatics — Posted on 2018-08-29

228 Successful optimization of reconstruction parameters in structured illumination microscopy - a practical guide

Karras, C.; Smedh, M.; Foerster, R.; Deschout, H.; Fernandez-Rodriguez, J.; Heintzmann, R.

10.1101/402115 — bioinformatics — Posted on 2018-08-29

229 HIV-1 Protease Uses Bi-Specific S2/S2’ Subsites To Optimize Cleavage of Two Classes of Target Sites

Potempa, M.; Lee, S.-K.; KurtYilmaz, N.; Nalivaika, E. A.; Rogers, A.; Spielvogel, E.; Carter, C. W.; Schiffer, C. A.; Swanstrom, R.

10.1101/404186 — biochemistry — Posted on 2018-08-29

230 Incorporation of doxorubicin in different polymer nanoparticles and their anti-cancer activity

Pieper, S.; Onafuye, H.; Mulac, D.; Cinatl, J.; Wass, M. N.; Michaelis, M.; Langer, K.

10.1101/403923 — pharmacology and toxicology — Posted on 2018-08-29

231 Evidence for minimal cardiogenic potential of Sca-1 positive cells in the adult mouse heart

Neidig, L. E.; Weinberger, F.; Palpant, N. J.; Mignone, J.; Martinson, A. M.; Sorensen, D.; Bender, I.; Nemoto, N.; Reinecke, H.; Pabon, L.; Molkentin, J. D.; Murry, C. E.; van Berlo, J.

10.1101/404038 — cell biology — Posted on 2018-08-29

232 Integrated Genomic Analysis of Hypoxia Genes across Cancer Types Identifies Significant Associations with Cancer Hallmarks

Yang, L.; Forker, L.; Fjeldbo, C.; Bristow, R.; Lyng, H.; West, C.

10.1101/403717 — cancer biology — Posted on 2018-08-29

233 Deformation microscopy for dynamic intracellular and intranuclear mapping of mechanics with high spatiotemporal resolution

Ghosh, S.; Seelbinder, B.; Henderson, J.; Watts, R.; Veress, A.; NEU, C. P.

10.1101/403261 — biophysics — Posted on 2018-08-29

234 Optimization of swelling response of pH sensitive hydrogels using Box-Behnken design

Shokri, F.; Ebrahimi, P.; Honary, S.

10.1101/403857 — bioengineering — Posted on 2018-08-29

235 A freeze-and-thaw induced-fragment of the microtubule-associated protein Tau in rat brain extracts: implications for the study of neurodegenerative diseases

Vasconcelos, I. C.; Schwaemmle, H. K.; Campos, R.; Masson, A. P.; Faca, V. M.; Garcia-Cairasco, N.; Sebollela, A.

10.1101/404129 — biochemistry — Posted on 2018-08-29

236 Cell type-dependent control of p53 transcription and enhancer activity by p63

Karsli Uzunbas, G.; Ahmed, F.; Sammons, M. A.

10.1101/268649 — genomics — Posted on 2018-08-29

237 Laminar Segregation of Sensory Coding and Behavioral Readout in Macaque V4

Pettine, W. W.; Steinmetz, N.; Moore, T.

10.1101/399626 — neuroscience — Posted on 2018-08-29

238 Nucl2Vec: Local alignment of DNA sequences using Distributed Vector Representation

Ganesh, P.; Gupta, G.; Saini, S.; Paul, K.

10.1101/401851 — genomics — Posted on 2018-08-29

239 Germline genomic landscapes of breast cancer patients significantly predict clinical outcomes

Milanese, J.-S.; Tibiche, C.; Zaman, N.; Zou, J.; Han, P.; Meng, Z. G.; Nantel, A.; Droit, A.; Wang, E.

10.1101/312355 — cancer biology — Posted on 2018-08-29

240 Self-Limiting Factors in Pandemics and Multi-Disease Syndemics

Manheim, D.

10.1101/401018 — epidemiology — Posted on 2018-08-29

241 Inpatient mobility to predict hospital-onset Clostridium difficile: a network approach

Bush, K.; Barbosa, H.; Farooq, S.; Weisenthal, S. J.; Trayhan, M.; White, R. J.; Ghoshal, G.; Zand, M. S.

10.1101/404160 — epidemiology — Posted on 2018-08-29

242 Levels of prescribing for four major antibiotic classes and rates of septicemia hospitalization in different US states

Goldstein, E.; Olesen, S.; Karaca, Z.; Steiner, C. A.; Viboud, C.; Lipsitch, M.

10.1101/404046 — epidemiology — Posted on 2018-08-29

243 Indication of spatially random infection of chlamydia-like organisms in Bufo bufo tadpoles from ponds located in the Geneva metropolitan area

Vajana, E.; Widmer, I.; Rochat, E.; Duruz, S.; Selmoni, O.; Vuilleumier, S.; Aeby, S.; Greub, G.; Joost, S.

10.1101/402487 — epidemiology — Posted on 2018-08-29

244 Modeling second-order boundary perception: A machine learning approach

DiMattina, C.; Baker, C. L.

10.1101/369041 — neuroscience — Posted on 2018-08-29

245 Heterogeneity in the respiratory symptoms of patients with mild-moderate COPD

Johnson, K. M.; Safari, A.; Tan, W. C.; Bourbeau, J.; FitzGerald, J. M.; Sadatsafavi, M.; Canadian Cohort of Obstructive Lung Disease (CanCOLD) study, ; Canadian Respiratory Research Network,

10.1101/401695 — epidemiology — Posted on 2018-08-29

246 Mycoplasma genitalium incidence, persistence, concordance between partners and progression: systematic review and meta-analysis

Cina, M.; Baumann, L.; Egli-Gany, D.; Halbeisen, F. S.; Ali, H.; Scott, P.; Low, N.

10.1101/400713 — epidemiology — Posted on 2018-08-29

247 Persistent DNA-break potential near telomeres increases initiation of meiotic recombination on short chromosomes

Subramanian, V. V.; Zhu, X.; Markowitz, T. E.; Vale Silva, L. A.; San-Segundo, P.; Hollingsworth, N. M.; Keeney, S.; Hochwagen, A.

10.1101/201889 — genomics — Posted on 2018-08-29

248 MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network with PRC2

Shivram, H.; Le, S. V.; Iyer, V. R.

10.1101/298919 — genomics — Posted on 2018-08-29

249 Mapping drinking water and quality of life aspects in urban settings: an application of the urban exposome

Andrianou, X. D.; van der Lek, C.; Charisiadis, P.; Ioannou, S.; Fotopoulou, K.; Papapanagiotou, Z.; Botsaris, G.; Beumer, C.; Makris, K. C.

10.1101/401927 — epidemiology — Posted on 2018-08-29

250 Disease persistence on temporal contact networks accounting for heterogeneous infectious periods

Darbon, A.; Colombi, D.; Valdano, E.; Savini, L.; Giovannini, A.; Colizza, V.

10.1101/401158 — epidemiology — Posted on 2018-08-29

251 Antimicrobial resistance prevalence and rates of hospitalization with septicemia in the diagnosis in adults in different US states

Goldstein, E.; MacFadden, D. R.; Karaca, Z.; Steiner, C. A.; Viboud, C.; Lipsitch, M.

10.1101/404137 — epidemiology — Posted on 2018-08-29

252 Evaluating cell lines as models for metastatic cancer through integrative analysis of open genomic data

Liu, K.; Newbury, P.; Glicksberg, B.; Zeng, W. Z.; Andrechek, E.; Chen, B.

10.1101/337287 — bioinformatics — Posted on 2018-08-29

253 End-to-end differentiable learning of protein structure

AlQuraishi, M.

10.1101/265231 — bioinformatics — Posted on 2018-08-29

254 Pat1 promotes processing body assembly by enhancing the phase separation of the DEAD-box ATPase Dhh1 and RNA

Sachdev, R.; Hondele, M.; Linsenmeier, M.; Vallotton, P.; Mugler, C. F.; Arosio, P.; Weis, K.

10.1101/402404 — biochemistry — Posted on 2018-08-29

255 Sparse-Coding Variational Auto-Encoders

Barello, G.; Charles, A.; Pillow, J.

10.1101/399246 — neuroscience — Posted on 2018-08-29

256 Quantifying the impact of dengue containment activities using high-resolution observational data

Abdur Rehman, N.; Salje, H.; Kraemer, M. U. G.; Subramanian, L.; Cauchemez, S.; Saif, U.; Chunara, R.

10.1101/401653 — epidemiology — Posted on 2018-08-29

257 Label-free digital holo-tomographic microscopy reveals virus-induced cytopathic effects in live cells

Yakimovich, A.; Witte, R.; Andriasyan, V.; Georgi, F.; Greber, U. F.

10.1101/401075 — cell biology — Posted on 2018-08-29

258 Pervasive contaminations in sequencing experiments are a major source of false genetic variability: a Mycobacterium tuberculosis meta-analysis

Goig, G. A.; Blanco, S.; Garcia-Basteiro, A.; Comas, I.

10.1101/403824 — genomics — Posted on 2018-08-29

259 Identification of a genetic element required for spore killing in Neurospora

Rhoades, N. A.; Harvey, A. M.; Samarajeewa, D. A.; Svedberg, J.; Yusifov, A.; Abusharekh, A.; Manitchotpisit, P.; Brown, D. W.; Sharp, K. J.; Rehard, D. G.; Peters, J.; Ostolaza-Maldonado, X.; Stephenson, J.; Shiu, P. K. T.; Johannesson, H.; Hammond, T. M.

10.1101/404004 — genetics — Posted on 2018-08-29

260 Trisomy 21 drives production of neurotoxic tryptophan catabolites via the interferon-inducible kynurenine pathway

Powers, R. K.; Sullivan, K. D.; Culp-Hill, R.; Ludwig, M. P.; Smith, K. P.; Waugh, K. A.; Minter, R.; Tuttle, K. D.; Rachubinski, A. L.; Granrath, R. E.; Wilkerson, R. B.; D'Alessandro, A.; Costello, J. C.; Espinosa, J. M.

10.1101/403642 — physiology — Posted on 2018-08-29

261 Association of SRB1, ITGB2 gene polymorphisms with coronary heart disease in Chinese Han population

Sun, Y.; Wang, L. T.; Zeng, Y.

10.1101/402792 — genetics — Posted on 2018-08-29

262 Effect of methylene blue on the formation of oxidized phospholipid vesicles

Fabre, J.-F.; Cerny, M.; Cassen, A.; Mouloungui, Z.

10.1101/403634 — bioengineering — Posted on 2018-08-29

263 Extrinsic and Intrinsic Dynamics in Movement Intermittency

Susilaradeya, D.; Xu, W.; Hall, T. M.; Galan, F.; Alter, K.; Jackson, A.

10.1101/402552 — neuroscience — Posted on 2018-08-29

264 Profound functional and molecular diversity of mitochondria revealed by cell type-specific profiling in vivo

Fecher, C.; Trovo, L.; Müller, S. A.; Snaidero, N.; Wettmarshausen, J.; Heink, S.; Ortiz, O.; Wagner, I.; Kühn, R.; Hartmann, J.; Karl, R. M.; Konnerth, A.; Korn, T.; Wurst, W.; Merkler, D.; Lichtenthaler, S. L.; Perocchi, F.; Misgeld, T.

10.1101/403774 — cell biology — Posted on 2018-08-29

265 Neighbor signals perceived by phytochrome B increase thermotolerance in Arabidopsis

Arico, D.; Legris, M.; Castro, L.; Garcia, C. F.; laino, A.; Casal, J. J.; Mazzella, M. A.

10.1101/403840 — plant biology — Posted on 2018-08-29

266 In vivo function of the lipid raft protein Flotillin 1 during CD8+ T cell-mediated host surveillance

Ficht, X.; Ruef, N.; Stolp, B.; Moalli, F.; Page, N.; Merkler, D.; Nichols, B. J.; Diz-Munoz, A.; Niggli, V.; Stein, J.

10.1101/403592 — immunology — Posted on 2018-08-29

267 The flower flies and the unknown diversity of Drosophilidae (Diptera): a biodiversity inventory in the Brazilian fauna

Schmitz, H. J.; Valente, V. L. d. S.

10.1101/402834 — zoology — Posted on 2018-08-29

268 Gender and international diversity improves equity in peer review

Murray, D.; Siler, K.; Lariviere, V.; Chan, W. M.; Collings, A. M.; Raymond, J.; Sugimoto, C. R.

10.1101/400515 — scientific communication and education — Posted on 2018-08-29

269 Autoantibodies and anti-microbial antibodies: Homology of the protein sequences of human autoantigens and the microbes with implication of microbial etiology in autoimmune diseases

Zhang, P.

10.1101/403519 — immunology — Posted on 2018-08-29

270 Saccharomyces cerevisiae goes through distinct metabolic phases during its replicative lifespan

Leupold, S.; Hubmann, G.; Litsios, A.; Meinema, A. C.; Papagiannakis, A.; Niebel, B.; Janssens, G.; Siegel, D.; Heinemann, M.

10.1101/403782 — cell biology — Posted on 2018-08-29

271 SIS-seq, a molecular ‘time machine’, connects single cell fate with gene programs

Luyi, T.; Schreuder, J.; Amann-Zalcenstein, D.; Tran, J.; Kocovski, N.; Su, S.; Diakumis, P.; Bahlo, M.; Sargeant, T.; Ritchie, M.; Hodgkin, P.; Naik, S.

10.1101/403113 — systems biology — Posted on 2018-08-29

272 Visual experience regulates the intrinsic excitability of visual cortical neurons to maintain sensory function

Brown, A. P.; Cossell, L.; Margrie, T. W.

10.1101/402768 — neuroscience — Posted on 2018-08-29

273 Characterization of nitrogen deposition by means of atmospheric biomonitors

Diaz-Alvarez, E. A.; de la Barrera, E.

10.1101/118257 — ecology — Posted on 2018-08-29

274 Dissecting differential signals in high-throughput data from complex tissues

Li, Z.; Wu, Z.; Peng, J.; Wu, H.

10.1101/402354 — bioinformatics — Posted on 2018-08-29

275 gFACs: Filtering, analysis, and conversion to unify genome annotations across alignment and gene prediction frameworks.

Caballero, M.; Wegrzyn, J.

10.1101/402396 — bioinformatics — Posted on 2018-08-29

276 Following the dung or the climate? Species richness pattern of dung beetles (Scarabaeinae) on the Americas

Medina, A. M.

10.1101/402537 — zoology — Posted on 2018-08-29

277 A model for physiological transmembrane transport derived from thermodynamical principles

Herrera-Valdez, M. A.

10.1101/403238 — physiology — Posted on 2018-08-29

278 Novelty and surprise-timing are broadcast by the basal forebrain

Zhang, K.; Chen, C. D.; Monosov, I. E.

10.1101/397513 — neuroscience — Posted on 2018-08-29

279 Age of onset in genetic prion disease and the design of preventive clinical trials

Minikel, E. V.; Vallabh, S. M.; Orseth, M. C.; Brandel, J.-P.; Haik, S.; Laplanche, J.-L.; Zerr, I.; Parchi, P.; Capellari, S.; Safar, J.; Kenny, J.; Fong, J. C.; Takada, L. T.; Ponto, C.; Hermann, P.; Knipper, T.; Stehmann, C.; Kitamoto, T.; Ae, R.; Hamaguchi, T.; Sanjo, N.; Tsukamoto, T.; Mizusawa, H.; Collins, S. J.; Chiesa, R.; Roiter, I.; de Pedro-Cuesta, J.; Calero, M.; Geschwind, M. D.; Yamada, M.; Nakamura, Y.; Mead, S.

10.1101/401406 — neuroscience — Posted on 2018-08-29

280 An homeotic post-transcriptional network controlled by the RNA-binding protein RBMX

Zuccotti, P.; Peroni, D.; Potrich, V.; Quattrone, A.; Dassi, E.

10.1101/400366 — genomics — Posted on 2018-08-29

281 Human Epigenetic Aging is Logarithmic with Time Across the Entire Lifespan

Snir, S.; Pellegrini, M.

10.1101/401992 — genomics — Posted on 2018-08-29

282 Homozygous TRPV4 loss-of-function mutation causes a severe form of distal Hereditary Motor Neuropathy (dHMN)

Marchetti, M. M.; Toth-Petroczy, A.; Grosgogeat, C. A.; Velilla, J.; Bennett, A. H.; Carmichael, N.; Estrella, E.; Darras, B. T.; Frank, N. Y.; Krier, J.; Gaudet, R.; Gupta, V. A.

10.1101/402388 — genetics — Posted on 2018-08-29

283 TreeBASEdmp: A Toolkit for Phyloinformatic Research

Piel, W. H.; Vos, R. A.

10.1101/399030 — evolutionary biology — Posted on 2018-08-29

284 Evolution of Bacterial Gene Transfer Agents

Redfield, R.; Soucy, S.

10.1101/402982 — evolutionary biology — Posted on 2018-08-29

285 A Modelling Exercise to Show Why Population Models Should Incorporate Distinct Life-Histories of Dispersers

Deere, J.; van den Berg, I.; Roth, G.; Smallegange, I.

10.1101/402198 — ecology — Posted on 2018-08-29

286 Arterio-Venous Remodeling in the Zebrafish Trunk Is Controlled by Genetic Programming and Flow-Mediated Fine-Tuning

Geudens, I.; Coxam, B.; Alt, S.; Gebala, V.; Vion, A.-C.; Rosa, A.; Gerhardt, H.

10.1101/403550 — cell biology — Posted on 2018-08-29

287 Cdc42 negatively regulates endocytosis during apical plasma membrane maintenance and development in mouse tubular organs in vivo

Shitara, A.; Malec, L.; Ebrahim, S.; Chen, D.; Bleck, C.; Hoffman, M. P.; Weigert, R.

10.1101/402677 — cell biology — Posted on 2018-08-29

288 Lineage calling can identify antibiotic resistant clones within minutes

Brinda, K.; Callendrello, A.; Cowley, L.; Charalampous, T.; Lee, R. S.; MacFadden, D. R.; Kucherov, G.; O'Grady, J.; Baym, M.; Hanage, W. P.

10.1101/403204 — bioinformatics — Posted on 2018-08-29

289 Functional Interpretation of Single-Cell Similarity Maps

DeTomaso, D.; Jones, M.; Subramaniam, M.; Ashuach, T.; Ye, C. J.; Yosef, N.

10.1101/403055 — bioinformatics — Posted on 2018-08-29

290 Prediction of Choice from Competing Mechanosensory and Choice-Memory Cues During Active Tactile Decision Making

Campagner, D.; Evans, M. H.; Chlebikova, K.; Colins-Rodriguez, A.; Loft, M. S.; Fox, S.; Pettifer, D.; Humphries, M. D.; Svoboda, K.; Petersen, R. S.

10.1101/400358 — animal behavior and cognition — Posted on 2018-08-29

291 Proteomics-based comparative mapping of the human brown and white adipocyte secretome reveals EPDR1 as a novel batokine

Deshmukh, A. S.; Peijs, L.; Nielsen, S.; Bayarri-Olmos, R.; Larsen, T. J.; Jespersen, N. Z.; Hattel, H.; Holst, B.; Garred, P.; Gerhart-Hines, Z.; Pedersen, B. K.; Mann, M.; Scheele, C.

10.1101/402867 — physiology — Posted on 2018-08-29

292 Brain connectivity dynamics: Multilayer network switching rate predicts brain performance

Pedersen, M.; Zalesky, A.; Omidvarnia, A.; Jackson, G. D.

10.1101/403105 — neuroscience — Posted on 2018-08-29

293 Elimination of vesicular zinc alters the behavioural and neuroanatomical effects of social defeat stress in mice

McAllister, B. B.; Wright, D. K.; Wortman, R. C.; Shultz, S. R.; Dyck, R. H.

10.1101/402891 — neuroscience — Posted on 2018-08-29

294 Decoupling of timescales reveals sparse convergent CPG network in the adult spinal cord

Radosevic, M.; Willumsen, A.; Petersen, P. C.; Linden, H.; Vestergaard, M.; Berg, R. W.

10.1101/402917 — neuroscience — Posted on 2018-08-29

295 What can facial mechanoreceptors tell the mouse brain about whisking?

Severson, K. S.; Xu, D.; Yang, H.; O'Connor, D.

10.1101/402883 — neuroscience — Posted on 2018-08-29

296 Unraveling the effects of spatial variability and relic DNA on the temporal dynamics of soil microbial communities

Carini, P.; Delgado-Baquerizo, M.; Hinckley, E.-L.; Brewer, T. E.; Rue, G.; Vanderburgh, C.; McKnight, D.; Fierer, N.

10.1101/402438 — microbiology — Posted on 2018-08-29

297 Competition within species determines the value of a mutualism between species

Sun, S.-J.; Horrocks, N. P. C.; Kilner, R. M.

10.1101/402271 — ecology — Posted on 2018-08-29

298 Avian diet and foraging ecology constrain foreign egg recognition and rejection

Luro, A. B.; Hauber, M. E.

10.1101/402941 — animal behavior and cognition — Posted on 2018-08-29

299 Sleep regulates visual selective attention in Drosophila

van Swinderen, B.; Kirszenblat, L.; Ertekin, D.; Goodsell, J.; Zhou, Y.; Shaw, P.

10.1101/403246 — animal behavior and cognition — Posted on 2018-08-29

300 Computation is concentrated in rich clubs of local cortical neurons

Faber, S. P.; Timme, N. M.; Beggs, J. M.; Newman, E. L.

10.1101/290981 — neuroscience — Posted on 2018-08-29

301 Antimicrobial Susceptibility Testing of Chlamydophila pneumoniae: Pilot Study for Alternative Methods that Address the Complex Chlamydial Life Cycle

Stratton, C. W.; Stewart, L. S.; Alvarez-Macias, s.; McHenry, R.; Chappell, J. D.

10.1101/403295 — microbiology — Posted on 2018-08-29

302 Novel Method for Viability Assessment of Bifidobacterium longum ATCC 15707 on Non-dairy Foods during drying

Min, M.; Mason, S. L.; Bennett, G. N.; Hussain, M. A.; Bunt, C. R.

10.1101/403287 — microbiology — Posted on 2018-08-29

303 Estimation of Rearrangement Break Rates Across the Genome

Hann-Soden, C.; Holmes, I.; Taylor, J. W.

10.1101/402933 — genomics — Posted on 2018-08-29

304 Efficient implementation of penalized regression for genetic risk prediction

Prive, F.; Aschard, H.; Blum, M. G. B.

10.1101/403337 — genetics — Posted on 2018-08-29

305 Convergent evolution of bird-mammal shared characteristics for adapting to nocturnality

Wu, Y.; Wang, H.

10.1101/403139 — evolutionary biology — Posted on 2018-08-29

306 Detecting overlapping spatial clusters of high sugar-sweetened beverage intake and high body mass index in a general population: a cross-sectional study

Joost, S.; De Ridder, D.; Marques-Vidal, P.; Bacchilega, B.; Theler, J.-M.; Gaspoz, J.-M.; Guessous, I.

10.1101/399584 — epidemiology — Posted on 2018-08-29

307 Anatomical and physiological foundations of cerebello-hippocampal interactions

Watson, T. C.; Obiang, P.; Torres-Herraez, A.; Watilliaux, A.; Coulon, P.; Rochefort, C.; Rondi-Reig, L.

10.1101/403394 — neuroscience — Posted on 2018-08-29

308 Paranoid schizophrenia and methamphetamine-induced paranoia are both characterized by a similar LINE-1 partial methylation profile, which is more pronounced in paranoid schizophrenia.

Kalayasiri, R.; Kraijak, K.; Mutirangura, A.; Maes, M.

10.1101/403535 — neuroscience — Posted on 2018-08-29

309 Transcriptome and histone epigenome of Plasmodium vivax salivary-gland sporozoites point to tight regulatory control and potential mechanisms for liver-stage differentiation.

10.1101/145250 — microbiology — Posted on 2018-08-29

310 Robust self-nonself discrimination requires negative T cell selection on non-random peptides

Wortel, I. M. N.; Kesmir, C.; De Boer, R. J.; Mandl, J. N.; Textor, J.

10.1101/403428 — immunology — Posted on 2018-08-29

311 Spatial Organization of Rho GTPase signaling by RhoGEF/RhoGAP proteins

Mueller, P. M.; Rademacher, J.; Bagshaw, R. D.; Alp, K. M.; Giudice, G.; Heinrich, L. E.; Barth, C.; Eccles, R. L.; Sanchez-Castro, M.; Brandenburg, L.; Mbamalu, G.; Tucholska, M.; Spatt, L.; Wortmann, C.; Czajkowski, M. T.; Welke, R. W.; Zhang, S.; Nguyen, V.; Rrustemi, T.; Trnka, P.; Freitag, K.; Larsen, B.; Popp, O.; Mertins, P.; Bakal, C.; Gingras, A.-C.; Pertz, O.; Roth, F. P.; Colwill, K.; Pawson, T.; Petsalaki, E.; Rocks, O.

10.1101/354316 — cell biology — Posted on 2018-08-29

312 An HIV-1 broadly neutralizing antibody from a clade C infected pediatric elite neutralizer potently neutralizes the contemporaneous and autologous evolving viruses

Kumar, S.; Panda, H.; Makhdoomi, M. A.; Mishra, N.; Safdari, H. A.; Aggarwal, H.; Reddy, E. S.; Lodha, R.; Kabra, S. K.; Chandele, A.; Dutta, S.; Luthra, K.

10.1101/403469 — immunology — Posted on 2018-08-29

313 Single-cell transcriptomics identifies drivers of local inflammation in multiple sclerosis

Schafflick, D.; Cole, M.; Hartlehnert, M.; Lautwein, T.; Buscher, K.; Wolbert, J.; Meuth, S. G.; Stettner, M.; Kleinschnitz, C.; Kuhlmann, T.; Gross, C. C.; Wiendl, H.; Yosef, N.; Meyer zu Horste, G.

10.1101/403527 — immunology — Posted on 2018-08-29

314 Chromatin-dependent cryptic promoters encode alternative protein isoforms in yeast.

Wei, W.; Hennig, B.; Wang, J.; Zhang, Y.; Chabbert, C. D.; Adjalley, S. H.; Steinmetz, L. M.; Pelechano, V.

10.1101/403543 — genomics — Posted on 2018-08-29

315 Development and validation of the Evaluation Platform In COPD (EPIC): a population-based outcomes model of COPD for Canada

Sadatsafavi, M.; Ghanbarian, S.; Adibi, A.; Johnson, K. M.; FitzGerald, J. M.; Flanagan, W.; Bryan, S.; Sin, D.; Canadian Respiratory Research Network,

10.1101/401745 — epidemiology — Posted on 2018-08-29

316 Multiple isotopic models using various kinetic fractionation coefficients to estimate δ18O of leaf water

Zhang, Y.; Yu, X.; Chen, L.; Jia, G.

10.1101/403410 — ecology — Posted on 2018-08-29

317 SWITCH-LIKE PHOSPHORYLATION OF WRN INTEGRATES END-RESECTION WITH REPAIR OF DSBs AT REPLICATION FORKS

Palermo, V.; Malacaria, E.; Sanchez, M.; Franchitto, A.; Pichierri, P.

10.1101/403808 — cell biology — Posted on 2018-08-29

318 Oxytocin promotes synchronized out-group attack during intergroup conflict in humans

Zhang, H.; Gross, J.; De Dreu, C.; Ma, Y.

10.1101/403790 — neuroscience — Posted on 2018-08-29

319 Structures in multiple conformations reveal distinct transition metal and proton pathways in an Nramp transporter

Bozzi, A. T.; Zimanyi, C. M.; Nicoludis, J. M.; Lee, B. K.; Zhang, C. H.; Gaudet, R.

10.1101/403014 — biochemistry — Posted on 2018-08-29

320 A size-invariant bud-duration timer enables robustness in yeast cell size control

Allard, C. A. H.; Decker, F.; Weiner, O. D.; Toettcher, J. E.; Graziano, B. R.

10.1101/211714 — cell biology — Posted on 2018-08-29

321 GLMdenoise improves multivariate pattern analysis of fMRI data

Charest, I.; Kriegeskorte, N.; Kay, K.

10.1101/320838 — neuroscience — Posted on 2018-08-29

322 Genetic dissection of assortative mating behavior

Merrill, R. M.; Rastas, P.; Melo, M.-C.; Martin, S. H.; Barker, S.; Davey, J.; McMillan, W. O.; Jiggins, C.

10.1101/282301 — evolutionary biology — Posted on 2018-08-29

323 Convergent temperature representations in artificial and biological neural networks

Haesemeyer, M.; Schier, A. F.; Engert, F.

10.1101/390435 — neuroscience — Posted on 2018-08-29

324 B cell receptor crosslinking can augment T cell help-mediated germinal center B cell selection.

Turner, J. S.; Ke, F.; Grigorova, I. L.

10.1101/300939 — immunology — Posted on 2018-08-29

325 Annexin A1 drives macrophage skewing towards a resolving phenotype to accelerate the regeneration of muscle injury through AMPK activation

McArthur, S.; Gobbetti, T.; Juban, G.; Desgeorges, T.; Theret, M.; Gondin, J.; Toller-Kawahisa, J.; Reutelingsperger, C.; Perretti, M.; Mounier, R.

10.1101/375709 — cell biology — Posted on 2018-08-29

326 Staufen2 mediated RNA recognition and localization requires combinatorial action of multiple domains

Heber, S.; Gaspar, I.; Tants, J.-N.; Günther, J.; Fernandez Moya, S. M.; Janowski, R.; Ephrussi, A.; Sattler, M.; Niessing, D.

10.1101/396994 — biochemistry — Posted on 2018-08-29

327 Hysteresis in the thermal relaxation dynamics of an immune complex as basis for molecular memory

Stan, R. C.; Camargo, M. M. d.

10.1101/398966 — biophysics — Posted on 2018-08-29

328 Restoration of visual function by transplantation of optogenetically engineered photoreceptors

Garita-Hernandez, M.; Lampic, M.; Chaffiol, A.; Guibbal, L.; Routet, F.; Santos-Ferreira, T.; Gagliardi, G.; Reichman, S.; Picaud, S.; Sahel, J.-A.; Goureau, O.; Ader, M.; Dalkara, D.; Duebel, J.

10.1101/399725 — bioengineering — Posted on 2018-08-29

329 Enterotype-like microbiome stratification as emergent structure in complex adaptive systems: A mathematical model.

Martin, M. A.

10.1101/402701 — systems biology — Posted on 2018-08-29

330 CTP synthase regulation by miR-975 controls cell proliferation and differentiation in Drosophila melanogaster

Woo, W.-K.; Dzaki, N.; Azzam, G.

10.1101/402024 — cell biology — Posted on 2018-08-29

331 Selective volume illumination microscopy offers synchronous volumetric imaging with high contrast

Truong, T. V.; Holland, D. B.; Madaan, S.; Andreev, A.; Troll, J. V.; Koo, D. E. S.; Keomanee-Dizon, K.; McFall-Ngai, M.; Fraser, S. E.

10.1101/403303 — biophysics — Posted on 2018-08-29

332 Extracellular matrix stiffness regulates force transmission pathways in multicellular ensembles of human airway smooth muscle cells.

Polio, S. R.; Stasiak, S.; Krishnan, R.; Parameswaran, H.

10.1101/402842 — bioengineering — Posted on 2018-08-29

333 A quantitative and predictive model for RNA binding by human Pumilio proteins

Jarmoskaite, I.; Denny, S. K.; Vaidyanathan, P. P.; Becker, W. R.; Andreasson, J. O. L.; Layton, C. J.; Kappel, K.; Shivashankar, V.; Sreenivasan, R.; Das, R.; Greenleaf, W. J.; Herschlag, D.

10.1101/403006 — biochemistry — Posted on 2018-08-29

334 FRMPD2: a novel GluN2A-interacting scaffold protein in synaptic excitatory transmission

Lu, X.; Wang, X.; Zhang, H.; Zhou, R.; He, M.; Li, Y.; Ma, Y.; Tian, X.

10.1101/403360 — neuroscience — Posted on 2018-08-29

335 Temporal dependence of shifts in mu opioid receptor mobility at the cell surface after agonist binding observed by single-particle tracking

Metz, M. J.; Pennock, R. L.; Krapf, D.; Hentges, S. T.

10.1101/402826 — neuroscience — Posted on 2018-08-29

336 Activation of polarized cell growth by inhibition of cell polarity

Geymonat, M.; Chessel, A.; Dodgson, J.; Punter, H.; Horns, F.; Csikasz-Nagy, A.; Carazo-Salas, R. E.

10.1101/402990 — cell biology — Posted on 2018-08-29

337 Construction and Characterization of a Synthetic Baculovirus-inducible 39K Promoter

Dong, Z.; Hu, Z.; Li, H.; Jiang, Y.; Cao, M.-Y.; Chen, P.; Lu, C.; Pan, M.

10.1101/403279 — bioengineering — Posted on 2018-08-29

338 Silk assembly integrates cells into a 3D fibrillar network that promotes cell spreading and proliferation

Johansson, U.; Widhe, M.; Shalaly, N. D.; Arregui, I. L.; Nileback, L.; Tasiopoulos, C. P.; Astrand, C.; Berggren, P.-O.; Gasser, C.; Hedhammar, M.

10.1101/403345 — bioengineering — Posted on 2018-08-29

339 Structures in multiple conformations reveal distinct transition metal and proton pathways in an Nramp transporter

Bozzi, A. T.; Zimanyi, C. M.; Nicoludis, J. M.; Lee, B. K.; Zhang, C. H.; Gaudet, R.

10.1101/403014 — biochemistry — Posted on 2018-08-29

340 Proton co-transport and voltage dependence enforce unidirectional metal transport in an Nramp transporter

Bozzi, A. T.; Zimanyi, C. M.; Bane, L. B.; Gaudet, R.

10.1101/402412 — biochemistry — Posted on 2018-08-29

341 Oncogenic activation of Nrf2 by specific knockout of Nrf1α that acts as a dominant tumor repressor

Qiu, L.; Wang, M.; Hu, S.; Ru, X.; Ren, Y.; Yu, S.; Zhang, Y.

10.1101/403220 — molecular biology — Posted on 2018-08-29

342 Fusion pore regulation by Epac2/cAMP controls cargo release during insulin exocytosis

Gucek, A.; Gandasi, N. R.; Omar-Hmeadi, M.; Bakke, M.; Doskeland, S. O.; Tengholm, A.; Barg, S.

10.1101/403253 — cell biology — Posted on 2018-08-29

343 Deformation microscopy for dynamic intracellular and intranuclear mapping of mechanics with high spatiotemporal resolution

Ghosh, S.; Seelbinder, B.; Henderson, J.; Watts, R.; Veress, A.; NEU, C. P.

10.1101/403261 — biophysics — Posted on 2018-08-29

344 Self-organizing motors divide active liquid droplets

Weirich, K. L.; Dasbiswas, K.; Witten, T. A.; Vaikuntanathan, S.; Gardel, M. L.

10.1101/403121 — biophysics — Posted on 2018-08-29

345 Concurrent infection with Mycobacterium tuberculosis confers robust protection against secondary infection in macaques

Flynn, J. L.; Cadena, A. M.; Hopkins, F. H.; Maiello, P.; Carey, A. F.; Wong, E. A.; Martin, C. J.; Gideon, H. P.; DiFazio, R. M.; Andersen, P.; Lin, P. L.; Fortune, S. M.

10.1101/403691 — microbiology — Posted on 2018-08-29

346 THE EVOLUTIONARY HISTORY OF THE OREXIN/ALLATOTROPIN GPCR FAMILY: FROM PLACOZOA AND CNIDARIA TO VERTEBRATA

Alzugaray, M. E.; Bruno, M. C.; Villalobos Sambucaro, M. J.; Ronderos, J. R.

10.1101/403709 — evolutionary biology — Posted on 2018-08-29

347 Expression of mammalian Onzin and Fungal Cadmium Resistance 1 in S. cerevisiae suggests ancestral functions of PLAC8 proteins in regulating mitochondrial metabolism and DNA damage repair

Daghino, S.; Di Vietro, L.; Petiti, L.; Martino, E.; Dallabona, C.; Lodi, T.; Perotto, S.

10.1101/403675 — cell biology — Posted on 2018-08-29

348 Automated literature mining and hypothesis generation through a network of Medical Subject Headings

Wilson, S.; Wilkins, A. D.; Holt, M. V.; Choi, B. K.; Konecki, D.; Lin, C.-H.; Koire, A.; Chen, Y.; Kim, S.-Y.; Wang, Y.; Wastuwidyaningtyas, B. D.; Qin, J.; Donehower, L. A.; Lichtarge, O.

10.1101/403667 — bioinformatics — Posted on 2018-08-29

349 Population based hospitalization burden of laboratory-confirmed hand, foot and mouth disease caused by multiple enterovirus serotypes in southern China

Yu, S.; Liao, Q.; Zhou, Y.; Hu, S.; Chen, Q.; Luo, K.; Chen, Z.; Luo, L.; Huang, W.; Dai, B.; He, M.; Liu, F.; Qiu, Q.; Ren, L.; Doorn, H. R. v.; Yu, H.

10.1101/403659 — epidemiology — Posted on 2018-08-29

350 General aspects of visceral leishmaniasis with or without HIV co-infection in Northeast Brazil

Azevedo, C. d. M.; Silva de Lima, U. R.; Vanolli, L.; Moraes, E. C.; Ithamar, J. S.; Uiara Regina Silva de Lima Luciano Vanolli Elizabeth Coelho Morais Jorim Ithamar Severino and Concei,

10.1101/403683 — epidemiology — Posted on 2018-08-29

351 High-throughput single-cell transcriptome profiling of plant cell types

Shulse, C. N.; Cole, B. J.; Turco, G. M.; Zhu, Y.; Brady, S. M.; Dickel, D. E.

10.1101/402966 — plant biology — Posted on 2018-08-29

352 Catalytic promiscuity potentiated the divergence of new cytochrome P450 enzyme functions in cyanogenic defense metabolism

Barco, B.; Zipperer, L.; Clay, N. K.

10.1101/398503 — evolutionary biology — Posted on 2018-08-29

353 Acetylation of nuclear localization signal controls importin-mediated nuclear transport of Ku70

Fujimoto, H.; Ikuta, T.; Koike, A.; Koike, M.

10.1101/403485 — cell biology — Posted on 2018-08-29

354 One read per cell per gene is optimal for single-cell RNA-Seq

Zhang, M. J.; Ntranos, V.; Tse, D.

10.1101/389296 — bioinformatics — Posted on 2018-08-28

355 Significant antitumour effect of an antibody against TMEM180, a new cancer-specific molecule

Yasunaga, M.; Saijou, S.; Hanaoka, S.; Anzai, T.; Tsumura, R.; Matsumura, Y.

10.1101/397844 — cancer biology — Posted on 2018-08-28

356 Progression of recent Mycobacterium tuberculosis exposure to active tuberculosis is a highly heritable complex trait driven by 3q23 in Peruvians

Luo, Y.; Suliman, S.; Asgari, S.; Amariuta, T.; Calderon, R.; Lecca, L.; Leon, S. R.; Jimenez, J.; Yataco, R.; Contreras, C.; Galea, J. T.; Becerra, M.; Nejentsev, S.; Martinez-Bonet, M.; Nigrovic, P. A.; Moody, D. B.; Murray, M. B.; Raychaudhuri, S.

10.1101/401984 — genetics — Posted on 2018-08-28

357 New tools for diet analyses: nanopore sequencing of metagenomic DNA from rat stomach contents to quantify diet

Pearman, W.; Smith, A. N. H.; Breckell, G.; Dale, J.; Freed, N. E.; Silander, O. K.

10.1101/363622 — ecology — Posted on 2018-08-28

358 A single cell transcriptomic analysis of human neocortical development

Polioudakis, D.; de la Torre-Ubieta, L.; Langerman, J.; Elkins, A. G.; Stein, J. L.; Vuong, C. K.; Opland, C. K.; Lu, D.; Connell, W.; Ruzzo, E. K.; Lowe, J. K.; Hadzic, T.; Hinz, F. I.; Sabri, S.; Lowry, W. E.; Plath, K.; Geschwind, D. H.

10.1101/401885 — neuroscience — Posted on 2018-08-28

359 Model-based assessment of public health impact and cost-effectiveness of dengue vaccination following screening for prior exposure

Espana, G.; Yao, Y.; Anderson, K. B.; Fitzpatrick, M. C.; Smith, D. L.; Morrison, A. C.; Wilder-Smith, A.; Scott, T. W.; Perkins, A.

10.1101/367060 — epidemiology — Posted on 2018-08-28

360 Quantifying the potential for future gene therapy to lower lifetime risk of polygenic late-onset diseases

Oliynyk, R. T.

10.1101/390773 — bioinformatics — Posted on 2018-08-28

361 Germline genomic landscapes of breast cancer patients significantly predict clinical outcomes

Milanese, J.-S.; Tibiche, C.; Zaman, N.; Zou, J.; Han, P.; Meng, Z. G.; Nantel, A.; Droit, A.; Wang, E.

10.1101/312355 — cancer biology — Posted on 2018-08-28

362 A Very Oil Yellow1 modifier of the Oil Yellow1-N1989 allele uncovers a cryptic phenotypic impact of cis-regulatory variation in maize

Khangura, R. S.; Marla, S.; Venkata, B. P.; Heller, N.; Johal, G. S.; Dilkes, B. P.

10.1101/230375 — genetics — Posted on 2018-08-28

363 Anti-angiogenic effects of VEGF stimulation on endothelium deficient in phosphoinositide recycling

Stratman, A. N.; Farrelly, O. M.; Mikelis, C. M.; Miller, M. F.; Wang, Z.; Pham, V. N.; Davis, A. E.; Burns, M. C.; Pezoa, S. A.; Castranova, D.; Kilts, T. M.; Davis, G. E.; Gutkind, J. S.; Pan, W.; Weinstein, B. M.

10.1101/402362 — cell biology — Posted on 2018-08-28

364 Identification of Small Molecule Modulators of Diguanylate Cyclase by FRET-based High-Throughput-Screening

Christen, M.; Kamischke, C.; Kulasekara, H. D.; Olivas, K. C.; Kulasekara, B. R.; Christen, B.; Kline, T.; Miller, S. I.

10.1101/402909 — biochemistry — Posted on 2018-08-28

365 Science podcasts: analysis of global production and output from 2004 to 2018

MacKenzie, L. E.

10.1101/298356 — scientific communication and education — Posted on 2018-08-28

366 Combining accurate tumour genome simulation with crowd-sourcing to benchmark somatic structural variant detection

Lee, A. Y.-W.; Ewing, A. D.; Ellrott, K.; Hu, Y.; Houlahan, K. E.; Bare, J. C.; Espiritu, S. M. G.; Huang, V.; Dang, K.; Chong, Z.; Caloian, C.; Yamaguchi, T. N.; ICGC-TCGA DREAM Somatic Mutation Calling Challenge Participants, ; Kellen, M. R.; Chen, K.; Norman, T. C.; Friend, S. H.; Guinney, J.; Stolovitzky, G.; Haussler, D.; Margolin, A. A.; Stuart, J. M.; Boutros, P. C.

10.1101/224733 — bioinformatics — Posted on 2018-08-28

367 The Fission Yeast S-Phase Cyclin Cig2 Can Drive Mitosis

Magner, M.; Pickering, M.; Keifenheim, D.; Rhind, N.

10.1101/213330 — cell biology — Posted on 2018-08-28

368 The UCSC Xena Platform for cancer genomics data visualization and interpretation

Goldman, M.; Craft, B.; Kamath, A.; Brooks, A. N.; Zhu, J.; Haussler, D.

10.1101/326470 — cancer biology — Posted on 2018-08-28

369 Assessment of population differentiation and linkage disequilibrium in Solanum pimpinellifolium using genome-wide high-density SNP markers

Lin, Y.-P.; Liu, C.-Y.; Chen, K.

10.1101/402420 — genetics — Posted on 2018-08-28

370 Pat1 promotes processing body assembly by enhancing the phase separation of the DEAD-box ATPase Dhh1 and RNA

Sachdev, R.; Hondele, M.; Linsenmeier, M.; Vallotton, P.; Mugler, C. F.; Arosio, P.; Weis, K.

10.1101/402404 — biochemistry — Posted on 2018-08-28

371 Sensitive period for cognitive repurposing of human visual cortex

Kanjlia, S.; Pant, R.; Bedny, M.

10.1101/402321 — neuroscience — Posted on 2018-08-28

372 De novo mutations drive the spread of macrolide resistant Mycoplasma genitalium: a mathematical modelling study

Cadosch, D.; Garcia, V.; Althaus, C. L.; Jensen, J. S.; Low, N.

10.1101/321216 — microbiology — Posted on 2018-08-28

373 Epigenetic signatures of starting and stopping smoking

McCartney, D. L.; Stevenson, A. J.; Hillary, R. F.; Walker, R. M.; Bermingham, M. L.; Morris, S. W.; Clarke, T.-K.; Campbell, A.; Murray, A. D.; Whalley, H. C.; Porteous, D.; Visscher, P. M.; McIntosh, A. M.; Evans, K. L.; Deary, I. J.; Marioni, R. E.

10.1101/402453 — genomics — Posted on 2018-08-28

374 Capturing diverse microbial sequence with comprehensive and scalable probe design

Metsky, H. C.; Siddle, K. J.; Gladden-Young, A.; Qu, J.; Yang, D. K.; Brehio, P.; Goldfarb, A.; Piantadosi, A.; Wohl, S.; Carter, A.; Lin, A. E.; Barnes, K. G.; Tully, D. C.; Corleis, B.; Hennigan, S.; Barbosa-Lima, G.; Vieira, Y. R.; Paul, L. M.; Tan, A. L.; Garcia, K. F.; Parham, L. A.; Odia, I.; Eromon, P.; Folarin, O. A.; Goba, A.; Viral Hemorrhagic Fever Consortium, ; Simon-Loriere, E.; Hensley, L.; Balmaseda, A.; Harris, E.; Kwon, D.; Allen, T. M.; Runstadler, J. A.; Smole, S.; Bozza, F. A.; Souza, T. M.; Isern, S.; Michael, S. F.; Lorenzana, I.; Gehrke, L.; Bosch, I.; Ebel, G.; Grant,

10.1101/279570 — genomics — Posted on 2018-08-28

375 The Rate of Molecular Evolution When Mutation May Not Be Weak

de Koning, A. P. J.; De Sanctis, B. D.

10.1101/259507 — genetics — Posted on 2018-08-28

376 The Evolution of Bequeathal in Stable Habitats

Clarke, P. M. R.; McElreath, M. B.; Barrett, B. J.; Mabry, K. E.; McElreath, R. L.

10.1101/336222 — evolutionary biology — Posted on 2018-08-28

377 Probing inhomogeneous diffusion in the microenvironments of phase-separated polymers under confinement

Shayegan, M.; Tahvildari, R.; Kisley, L.; Metera, K.; Michnick, S. W.; Leslie, S. R.

10.1101/402230 — biophysics — Posted on 2018-08-28

378 Investigating the deregulation of metabolic tasks via Minimum Network Enrichment Analysis (MiNEA) as applied to nonalcoholic fatty liver disease using mouse and human omics data

Pandey, V.; Hatzimanikatis, V.

10.1101/402222 — systems biology — Posted on 2018-08-28

379 Activation of innate immune responses by a CpG oligonucleotide sequence composed entirely of threose nucleic acid.

Lange, M. J.; Burke-Aguero, D. H.; Chaput, J.

10.1101/401612 — synthetic biology — Posted on 2018-08-28

380 Deep Learning for Quality Control of Subcortical Brain 3D Shape Models

Petrov, D.; Gutman, B. A.; Kuznetsov, E.; van Erp, T. G. M.; Turner, J. A.; Schmaal, L.; Veltman, D.; Wang, L.; Alpert, K.; Isaev, D.; Zavaliangos-Petropolu, A.; Ching, C. R. K.; Calhoun, V.; Glahn, D.; Satterthwaite, T. D.; Andreassen, O. A.; Borgwardt, S.; Howells, F.; Groenewold, N.; Voineskos, A.; Radua, J.; Potkin, S. G.; Crespo-Favorro, B.; Tordesillas-Gutirrez, D.; Shen, L.; Lebedeva, I.; Spalletta, G.; Donohoe, G.; Kochunov, P.; Rosa, P. G. P.; James, A.; Dannlowski, U.; Baune, B. T.; Aleman, A.; Gotlib, I. H.; Walter, H.; Walter, M.; Soarez, J. C.; Ehrlich, S.; Gur, R. C.; Doan, N. T.

10.1101/402255 — neuroscience — Posted on 2018-08-28

381 Poor coherence in older people’s speech is explained by impaired semantic and executive processes

Hoffman, P.; Loginova, E.; Russell, A.

10.1101/320473 — neuroscience — Posted on 2018-08-28

382 Single-cell analysis reveals the KIT D816V mutation in hematopoietic stem and progenitor cells in systemic mastocytosis

Grootens, J.; Ungerstedt, J. S.; Ekoff, M.; Rönnberg Höckerlind, E.; Klimkowska, M.; Amini, R.-M.; Arock, M.; Söderlund, S.; Mattsson, M.; Nilsson, G.; Dahlin, J. S.

10.1101/394304 — immunology — Posted on 2018-08-28

383 Eco-evolutionary agriculture: a study in crop rotations

Bargues-Ribera, M.; Gokhale, C. S.

10.1101/402313 — evolutionary biology — Posted on 2018-08-28

384 EBADIMEX: An empirical Bayes approach to detect joint differential expression and methylation and to classify samples

Madsen, T.; Switnicki, M. P.; Juul, M.; Pedersen, J. S.

10.1101/401232 — bioinformatics — Posted on 2018-08-28

385 Lead-DBS v2: Towards a comprehensive pipeline for deep brain stimulation imaging

Horn, A.; Li, N.; Dembek, T. A.; Kappel, A.; Boulay, C.; Ewert, S.; Tietze, A.; Husch, A.; Perera, T.; Neumann, W.-J.; Reisert, M.; Si, H.; Oostenveld, R.; Rorden, C.; Yeh, F.-C.; Fang, Q.; Herrington, T. M.; Vorwerk, J.; Kuehn, A. A.

10.1101/322008 — neuroscience — Posted on 2018-08-28

386 Simultaneous multiplexed amplicon sequencing and transcriptome profiling in single cells

Saikia, M.; Burnham, P.; Keshavjee, S. H.; Wang, M. F. Z.; Heyang, M.; Moral-Lopez, P.; Hinchman, M. M.; Danko, C. G.; Parker, J. S. L.; De Vlaminck, I.

10.1101/328328 — genomics — Posted on 2018-08-28

387 Chemotactic behavior of Escherichia coli at high cell density

Colin, R.; Sourjik, V.

10.1101/402289 — biophysics — Posted on 2018-08-28

388 Small Data Challenge: Structural Analysis and Optimization of Convolutional Neural Networks with a Small Sample Size

D'souza, R. N.; Huang, P.-Y.; Yeh, F.-C.

10.1101/402610 — bioengineering — Posted on 2018-08-28

389 Instability in 18S and 5.8S rDNA copy numbers and 18S:5.8S ratios in longitudinally-collected human DNA samples detected by monochrome multiplex qPCR

Ligerman, C. B.; Baird, L.; Leppert, M. F.; Cawthon, R. M.

10.1101/361840 — genomics — Posted on 2018-08-28

390 The regulatory control of Cebpa enhancers and silencers in the myeloid and red-blood cell lineages

Repele, A.; Krueger, S.; Tuineau, M. Y.; Manu, M.

10.1101/369553 — developmental biology — Posted on 2018-08-28

391 A randomised controlled trial of an Intervention to Improve Compliance with the ARRIVE guidelines (IICARus)

Hair, K.; Macleod, M. R.; Sena, E. S.; The IICARus Collaboration,

10.1101/370874 — scientific communication and education — Posted on 2018-08-28

392 Overexpression of Arabidopsis ubiquitin ligase AtPUB46 enhances tolerance to drought and oxidative stress

Adler, G.; Mishra, A. K.; Maymon, T.; Raveh, D.; Bar-Zvi, D.

10.1101/379859 — plant biology — Posted on 2018-08-28

393 Screening Mycobacterium tuberculosis secreted proteins identifies Mpt64 as eukaryotic membrane-binding virulence factor

Stamm, C. E.; Pasko, B. L.; Chaisavaneeyakorn, S.; Franco, L. H.; Nair, V. R.; Weigele, B. A.; Alto, N. M.; Shiloh, M. U.

10.1101/402099 — microbiology — Posted on 2018-08-28

394 Genomic response to selection for diurnality and nocturnality in Drosophila

Pegoraro, M.; Flavell, L. M.; Menegazzi, P.; Colombi, P.; Dao, P.; Charlotte Helfrich-Förster, C.; Tauber, E.

10.1101/380733 — evolutionary biology — Posted on 2018-08-28

395 FastqCleaner: an interactive Bioconductor application for quality-control, filtering and trimming of FASTQ files

Roser, L. G.; Agüero, F.; Sanchez, D.

10.1101/393140 — bioinformatics — Posted on 2018-08-28

396 A comprehensive genomics solution for HIV surveillance and clinical monitoring in a global health setting

Bonsall, D.; Golubchik, T.; de Cesare, M.; Limbada, M.; Kosloff, B.; MacIntyre-Cockett, G.; Hall, M.; Wymant, C.; Ansari, A.; Abeler-Dorner, L.; Schaap, A.; Brown, A.; Barnes, E.; Piwowar-Manning, E.; Wilson, E.; Emel, L.; Hayes, R.; Fidler, S.; Ayles, H.; Bowden, R.; Fraser, C.

10.1101/397083 — genomics — Posted on 2018-08-28

397 EGFR signaling coordinates patterning with cell survival during Drosophila epidermal development

Crossman, S. H.; Streichan, S. J.; Vincent, J.-P.

10.1101/399865 — developmental biology — Posted on 2018-08-28

398 Visual intensity ratio modulates operant learning responses in larval zebrafish

Yang, W.; Meng, Y.; Li, D.; Wen, Q.

10.1101/401000 — neuroscience — Posted on 2018-08-28

399 Signatures of negative frequency dependent selection in colonisation factors and the evolution of a multi-drug resistant lineage of Escherichia coli

McNally, A.; Kallonen, T.; Connor, C.; Abudahab, K.; Aanensen, D.; Horner, C.; Peacock, S.; Parkhill, J.; Croucher, N.; Corander, J.

10.1101/400374 — microbiology — Posted on 2018-08-28

400 High resolution evolutionary analysis of within-host hepatitis C virus infection

Raghwani, J.; Wu, C.-H.; Ho, C. K.; de Jong, M.; Molenkamp, R.; Schinkel, J.; Pybus, O. G.; Lythgoe, K. A.

10.1101/400283 — evolutionary biology — Posted on 2018-08-28

401 Stability of host-parasite systems: you must differ to coevolve

Berezovskaya, F. S.; Karev, G. P.; Katsnelson, M. I.; Wolf, Y. I.; Koonin, E. V.

10.1101/400150 — evolutionary biology — Posted on 2018-08-28

402 The Emotional Glue of the Senses: Affective Certainty and Congruency in the Rubber Hand Illusion

Filippetti, M. L.; Kirsch, L. P.; Crucianelli, L.; Fotopoulou, A.

10.1101/401422 — neuroscience — Posted on 2018-08-28

403 Superresolution architecture of pluripotency guarding adhesions

Stubb, A.; Guzman, C.; Närvä, E.; Aaron, J.; Chew, T.-L.; Saari, M.; Miihkinen, M.; Jacquemet, G.; Ivaska, J.

10.1101/402305 — cell biology — Posted on 2018-08-28

404 Task-specific vision models explain task-specific areas ofvisual cortex

Dwivedi, K.; Roig, G.

10.1101/402735 — neuroscience — Posted on 2018-08-28

405 GI-16 lineage (624/I or Q1), there and back again: the history of one of the major threat for poultry farming of our era

Moreno, A.; Franzo, G.; Cecchinato, M.; Tosi, G.; Fiorentini, L.; Faccin, F.; Tucciarone, C. M.; Trogu, T.; Barbieri, I.; Massi, P.

10.1101/402800 — evolutionary biology — Posted on 2018-08-28

406 Epidemiology of Cancers in Zambia: A Significant Variation in Cancer Incidence and Prevalence across the Nation

Kalubula, m.; Liu, L.; Shen, H.; Makasa, M.

10.1101/402628 — epidemiology — Posted on 2018-08-28

407 Temporally varying isotopic niche overlap of the invasive ctenophore Mnemiopsis leidyi with other zooplanktivores in the western Dutch Wadden Sea

van Walraven, L.; van Looijengoed, W.; Jung, S.; Langenberg, V.; van der Veer, H.

10.1101/402602 — ecology — Posted on 2018-08-28

408 Implantable electrical stimulation bioreactor with liquid crystal polymer based electrodes for enhanced bone regeneration at mandibular large defects in rabbit

Kim, C.; Yang, H. J.; Cho, T. H.; Lee, B.; Gwon, T. M.; Shin, S.; Kim, I. S.; Kim, S. J.; Hwang, S. J.

10.1101/402719 — bioengineering — Posted on 2018-08-28

409 Limits to the rate of information transmissionthrough MAPK pathway

Grabowski, F.; Czyz, P.; Kochanczyk, M.; Lipniacki, T.

10.1101/402750 — systems biology — Posted on 2018-08-28

410 Computational imperfections in human visual search

Stengard, E.; van den Berg, R.

10.1101/402776 — neuroscience — Posted on 2018-08-28

411 MiR-505-3p is a Repressor of the Puberty Onset in Female Mice

Zhou, Y.; tong, l.; wang, m.; chang, x.; wang, s.; li, k.; Xiao, J.

10.1101/402784 — genetics — Posted on 2018-08-28

412 A natural history model for planning prostate cancer testing: calibration and validation using Swedish registry data

Karlsson, A.; Jauhiainen, A.; Gulati, R.; Eklund, M.; Grönberg, H.; Etzioni, R.; Clements, M.

10.1101/402743 — epidemiology — Posted on 2018-08-28

413 Over-expression of the photoperiod response regulator ZmCCT10 modifies plant architecture, flowering time and inflorescence morphology in maize

Stephenson, E.; Estrada, S.; Meng, X.; Ourada, J.; Muszynski, M. G.; Habben, J. E.; Danilevskaya, O.

10.1101/402586 — developmental biology — Posted on 2018-08-28

414 An open-source software analysis package for Microspheres with Ratiometric Barcode Lanthanide Encoding (MRBLEs)

Harink, B.; Nguyen, H.; Thorn, K.; Fordyce, P.

10.1101/402560 — bioengineering — Posted on 2018-08-28

415 Enterotype-like microbiome stratification as emergent structure in complex adaptive systems: A mathematical model.

Martin, M. A.

10.1101/402701 — systems biology — Posted on 2018-08-28

416 Resting shear elastic modulus as a marker of peripheral fatigue during maximal isometric contractions in humans

SIRACUSA, J.; CHARLOT, K.; MALGOYRE, A.; CONORT, S.; TARDO-DINO, P.-E.; BOURRILHON, C.; GARCIA-VICENCIO, S.

10.1101/402644 — physiology — Posted on 2018-08-28

417 Psidium guajava in the Galapagos Islands: population genetics and history of an invasive species

Urquia, D.; Gutierrez, B.; Pozo, G.; Pozo, M. J.; Espin, A.; Torres, M. d. L.

10.1101/402693 — evolutionary biology — Posted on 2018-08-28

418 Access to and use of preventive intermittent treatment for Malaria during pregnancy: a qualitative study in Chokwe district, Southern Mozambique

Arnaldo, P.; Cambe, I.; Magasso, A.; Chicumbe, S.; Rovira-Vallbona, E.; Rosanas-Urgell, A.; Enosse, S.

10.1101/402727 — epidemiology — Posted on 2018-08-28

419 Stable changing fluid shear stress promotes osteogenesis

Wang, L.; Xiao, F.; Lei, Y.; Su, H.; Yang, Y.; Wang, S.

10.1101/402651 — cell biology — Posted on 2018-08-28

420 CARDIOMETABOLIC RECOVERY AND LACTATE REMOVAL MAY BE RELATED TO MUSCULAR ADAPTATIONS

Meza, E. I. A.; de-Oliveira, G. L.; Perini-de-Oliveira, T. A.; Moreira, M. H.; Militao, A. G.; Fernandes-Filho, J.; Furtado-da-Silva, V.; Dantas, E. H. M.; Valentim-Silva, J. R.

10.1101/402511 — physiology — Posted on 2018-08-28

421 Establishment of baseline sensitivity of Rhizoctonia solani to thifluzamide in corn and its field application

shang, d.; Yao, C.; He, F.; Li, X.; Zhang, J.; Jiang, X.; Sun, X.; Sun, S.; Tan, H.; Chentao Yao, Falin He, Xiao Sun, Shiang Sun, Haili Tan, Xiangdong Li, Jiwang Zhang, Xingyin Jiang,

10.1101/402529 — pathology — Posted on 2018-08-28

422 Montastraea cavernosa corallite structure demonstrates ‘shallow-only’ and ‘depth-generalist’ morphotypes across shallow and mesophotic depth zones in the Gulf of Mexico

Studivan, M. S.; Milstein, G.; Voss, J. D.

10.1101/402636 — ecology — Posted on 2018-08-28

423 Extracellular Adenine Nucleotide and Adenosine Metabolism in Calcific Aortic Valve Disease

Kutryb-Zajac, B.; Jablonska, P.; Serocki, M.; Bulinska, A.; Mierzejewska, P.; Friebe, D.; Alter, C.; Jasztal, A.; Lango, R.; Rogowski, J.; Bartoszewski, R.; Slominska, E. M.; Chlopicki, S.; Schrader, J.; Yacoub, M. H.; Smolenski, R. T.

10.1101/402685 — biochemistry — Posted on 2018-08-28

424 The effect of community dialogues and sensitization on patient reporting of adverse events in rural Uganda: uncontrolled before-after study

Ndagije, H. B.; Manirakiza, L.; Kajungu, D.; Galiwango, E.; Kusemererwa, D. A.; Olsson, S.; Spinewine, A.; Speybroeck, N.

10.1101/402503 — scientific communication and education — Posted on 2018-08-28

425 Gridlock from Diagnosis to Treatment of Multidrug Resistant Tuberculosis in Tanzania: Patients Perspectives from the Focus Group Discussion

Mpagama, S. G.; Mangi, E.; Mbelele, P. M.; Chongolo, A. M.; Kibiki, G. S.; Heysell, S. K.

10.1101/402594 — scientific communication and education — Posted on 2018-08-28

426 Electrical Fields Induced Inside the Rat Brain with Skin, Skull, and Dural Placements of the Current Injection Electrode

Asan, A. S.; Gok, S.; Sahin, M.

10.1101/402578 — neuroscience — Posted on 2018-08-28

427 The genome of Ectocarpus subulatus highlights unique mechanisms for stress tolerance in brown algae

Dittami, S. M.; Corre, E.; Brillet-Gueguen, L.; Pontoizeau, N.; Aite, M.; Avia, K.; Caron, C.; Cho, C. H.; Collen, J.; Cormier, A.; Delage, L.; Doubleau, S.; Frioux, C.; Gobet, A.; Gonzalez-Navarrete, I.; Groisillier, A.; Herve, C.; Jollivet, D.; KleinJan, H.; Leblanc, C.; Lipinska, A. P.; Liu, X.; Marie, D.; Markov, G. V.; Minoche, A. E.; Monsoor, M.; Pericard, P.; Perrineau, M.-M.; Peters, A. F.; Siegel, A.; Simeon, A.; Trottier, C.; Yoon, H. S.; Himmelbauer, H.; Boyen, C.; Tonon, T.

10.1101/307165 — genomics — Posted on 2018-08-28

428 Genetic dissection of assortative mating behavior

Merrill, R. M.; Rastas, P.; Melo, M.-C.; Martin, S. H.; Barker, S.; Davey, J.; McMillan, W. O.; Jiggins, C.

10.1101/282301 — evolutionary biology — Posted on 2018-08-28

429 Biogeography of the savanna-like vegetation in hot dry valleys in southwestern China with reference to their floristic origin and evolution

Zhu, H.; Yan, L.

10.1101/402545 — ecology — Posted on 2018-08-28

430 Role of STING complex in differential retrograde signaling in cybrids with K versus H haplogroup mtDNA

Schneider, K.; Chwa, M.; Atilano, S. R.; Nashine, S.; Udar, N.; Boyer, D. S.; Jazwinski, S. M.; Miceli, M. V.; Nesburn, A. B.; Kuppermann, B. D.; Kenney, M. C.

10.1101/402495 — cell biology — Posted on 2018-08-28

431 Reconstructing imagined letters from early visual cortex reveals tight topographic correspondence between visual mental imagery and perception

Senden, M.; Emmerling, T. C.; Van Hoof, R.; Frost, M.; Goebel, R.

10.1101/277020 — neuroscience — Posted on 2018-08-28

432 Hepatitis B mother-to-child transmission in the Eastern Region of Ghana: A cross-sectional pilot study

Hambridge, T.; Nartey, Y.; Duah, A.; Plymoth, A.

10.1101/402479 — immunology — Posted on 2018-08-28

433 A plant biodiversity effect resolved to a single genetic locus

Wuest, S. E.; Niklaus, P. A.

10.1101/264960 — ecology — Posted on 2018-08-28

434 Description of novel marine bioflocculant-producing bacteria isolated from biofloc of pacific whiteleg shrimp, Litopenaeus vannamei culture ponds

che hashim, n. f.; ghazali, n. a.; kasan, n. a.; Ismail, N.; Mat Amin, N.

10.1101/402065 — microbiology — Posted on 2018-08-28

435 Screening Mycobacterium tuberculosis secreted proteins identifies Mpt64 as eukaryotic membrane-binding virulence factor

Stamm, C. E.; Pasko, B. L.; Chaisavaneeyakorn, S.; Franco, L. H.; Nair, V.; Weigele, B. A.; Alto, N. M.; Shiloh, M. U.

10.1101/402099 — microbiology — Posted on 2018-08-28

436 In Silico Identification of Three Types of Integrative and Conjugative Elements (ICEs) in Elizabethkingia anophelis Strains Isolated from Around the World

Xu, J.; Pei, D.; Nicholson, A. C.; Lan, Y.; Xia, Q.

10.1101/402107 — genomics — Posted on 2018-08-28

437 Progression of recent Mycobacterium tuberculosis exposure to active tuberculosis is a highly heritable complex trait driven by 3q23 in Peruvians

10.1101/401984 — genetics — Posted on 2018-08-28

438 Enemy release mitigates inbreeding depression in native and invasive Silene latifolia populations: experimental insight into the role of inbreeding x environment interactions in invasion success

Schrieber, K.; Wolf, S.; Wypior, C.; Hoehlig, D.; Keller, S.; Hensen, I.; Lachmuth, S.

10.1101/401430 — evolutionary biology — Posted on 2018-08-28

439 Defining and Evaluating Microbial Contributions to Metabolite Variation in Microbiome-Metabolome Association Studies

Noecker, C.; Chiu, H.-C.; McNally, C. P.; Borenstein, E.

10.1101/402040 — microbiology — Posted on 2018-08-28

440 Genomic data provides new insights on the demographic history and the extent of recent material transfers in Norway spruce

Chen, J.; li, l.; Milesi, P.; Jansson, G.; Berlin, M.; Karlsson, B.; Aleksic, J.; Vendramin, G. G.; Lascoux, M.

10.1101/402016 — evolutionary biology — Posted on 2018-08-28

441 Plasticity and environmental heterogeneity predict geographic resilience patterns of foundation species to future change

Telesca, L.; Peck, L. S.; Sanders, T.; Thyrring, J.; Sejr, M. K.; Harper, E. M.

10.1101/401588 — ecology — Posted on 2018-08-28

442 Computational Analysis of Dynamical Fluctuations of Oncoprotein E7 (HPV) for the Hot Spot Residue Identification Using Elastic Network Model

Malik, R. M.; Nazir, F.; Fazal, S.; Ullah, M.; Malik, S. I.; Kanwal, A.; Aziz, S. E.; Azam, S.

10.1101/401646 — bioinformatics — Posted on 2018-08-28

443 The interaction between ORF18 and ORF30 is required for late gene transcription in Kaposi’s sarcoma-associated herpesvirus

Castaneda, A. F.; Glaunsinger, B. A.

10.1101/401976 — molecular biology — Posted on 2018-08-28

444 Potential for microbial anaerobic hydrocarbon degradation in naturally occurring petroleum-associated deep-sea sediments

DONG, X.; Greening, C.; Rattray, J. E.; Chakraborty, A.; Chuvochina, M.; Mayumi, D.; Li, C.; Brooks, J. M.; Bernard, B. B.; Groves, R. A.; Lewis, I. A.; Hubert, C. R. J.

10.1101/400804 — microbiology — Posted on 2018-08-28

445 Metabolic Flux Hierarchy Prioritizes the Entner-Doudoroff Pathway for Carbohydrate Co-Utilization in Pseudomonas protegens Pf-5

Wilkes, R. A.; Mendonca, C. M.; Aristilde, L.

10.1101/402073 — microbiology — Posted on 2018-08-28

446 Whole genome sequencing for drug resistance profile prediction in Mycobacterium tuberculosis

Gygli, S. M.; Keller, P. M.; Ballif, M.; Blöchliger, N.; Hömke, R.; Reinhard, M.; Loiseau, C.; Ritter, C.; Sander, P.; Borrell, S.; Loo, J. C.; Avihingsanon, A.; Gnokoro, J.; Yotebieng, M.; Egger, M.; Gagneux, S.; Böttger, E. C.

10.1101/401703 — microbiology — Posted on 2018-08-28

447 Finally, Bulk Typing of Bacterial Species down to Strain Level using ON-rep-seq

Krych, L.; Leonardo Castro Mejia, J.; Norgaard Moesby, D.; Baastrup Mikkelsen, M.; Arendt Rasmussen, M.; Sykulski, M.; Sandris Nielsen, D.

10.1101/402156 — microbiology — Posted on 2018-08-28

448 Optimizing non-invasive sampling of an infectious bat virus

Giles, J. R.; Peel, A. J.; Wells, K.; Plowright, R. K.; McCallum, H.; Restif, O.

10.1101/401968 — ecology — Posted on 2018-08-28

449 Genetic structure of invasive babys breath (Gypsophila paniculata) populations in a freshwater Michigan dune system

Leimbach-Maus, H. B.; Parks, S. R.; Partridge, C. G.

10.1101/401950 — plant biology — Posted on 2018-08-28

450 Frontal and occipito-temporal Theta activity as marker of error monitoring in Human-Avatar joint performance.

Moreau, Q.; Candidi, M.; Era, V.; Tieri, G.; Aglioti, S. M.

10.1101/402149 — neuroscience — Posted on 2018-08-28

451 Expression of a recombinant, 4’-Phosphopantetheinylated, active M. tuberculosis Fatty acid Synthase I in E. coli

Baron, S.; Peleg, Y.; Grunwald, J.; Morgenstern, D.; Elad, N.; Peretz, M.; Albeck, S.; Levin, Y.; Welch, J. T.; Deweerd, K. A.; Schwartz, A.; Burstein, Y.; Diskin, R.; Shakked, Z.; Zimhony, O.

10.1101/400622 — microbiology — Posted on 2018-08-28

452 PP2AB55δ Responsible for the High Initial Rates of Alcoholic Fermentation in Sake Yeast Strains of Saccharomyces cerevisiae

Watanabe, D.; Kajihara, T.; Sugimoto, Y.; Takagi, K.; Mizuno, M.; Zhou, Y.; Chen, J.; Takeda, K.; Tatebe, H.; Shiozaki, K.; Nakazawa, N.; IZAWA, S.; Akao, T.; Shimoi, H.; Maeda, T.; Takagi, H.

10.1101/402081 — microbiology — Posted on 2018-08-28

453 Nucl2Vec: Local alignment of DNA sequences using Distributed Vector Representation

Ganesh, P.; Gupta, G.; Saini, S.; Paul, K.

10.1101/401851 — genomics — Posted on 2018-08-28

454 Basolateral localization of MMP14 drives apicobasal polarity change during EMT independently of its catalytic activity

Andrieu, C.; Montigny, A.; Alfandari, D.; Theveneau, E.

10.1101/402180 — developmental biology — Posted on 2018-08-28

455 Activation mechanism of ATP-sensitive K+ channels explored with real-time nucleotide binding

Puljung, M.; Vedovato, N.; Usher, S.; Ashcroft, F. M.

10.1101/402206 — biophysics — Posted on 2018-08-28

456 IsoformSwitchAnalyzeR: Analysis of changes in genome-wide patterns of alternative splicing and its functional consequences

Vitting-Seerup, K.; Sandelin, A.

10.1101/399642 — bioinformatics — Posted on 2018-08-28

457 Dot6 is a major regulator of cell size and a transcriptional activator of ribosome biogenesis in the opportunistic yeast Candida albicans

Chaillot, J.; Malick, J.; Sellam, A.

10.1101/401778 — cell biology — Posted on 2018-08-28

458 The RNA-Binding Protein DND1 Acts Sequentially as a Negative Regulator of Pluripotency and a Positive Regulator of Epigenetic Modifiers Required for Germ Cell Reprogramming

Ruthig, V. A.; Friedersdorf, M. B.; Garness, J. A.; Munger, S. C.; Bunce, C.; Keene, J. D.; Capel, B.

10.1101/402008 — cell biology — Posted on 2018-08-28

459 CTP synthase regulation by miR-975 controls cell proliferation and differentiation in Drosophila melanogaster

Woo, W.-K.; Dzaki, N.; Azzam, G.

10.1101/402024 — cell biology — Posted on 2018-08-28

460 Comparing the efficacy of cancer therapies between subgroups in basket trials

Palmer, A. C.; Plana, D.; Sorger, P.

10.1101/401620 — cancer biology — Posted on 2018-08-28

461 Self-organization controls expression more than abundance of molecular components of transcription and translation in confined cell-free gene expression

Caveney, P.; Dabbs, R.; Chauhan, G.; Norred, S.; Collier, P.; Abel, S.; Simpson, M.

10.1101/401794 — biophysics — Posted on 2018-08-28

462 Molecular Heterogeneity and Early Metastatic Clone Selection in Testicular Germ Cell Cancer Development

Dorssers, L. C.; Gillis, A. J.; Stoop, H.; van Marion, R.; Nieboer, M. M.; van Riet, J.; van de Werken, H. J.; Oosterhuis, J. W.; de Ridder, J.; Looijenga, L. H.

10.1101/385807 — cancer biology — Posted on 2018-08-28

463 Ventral tegmental area astrocytes orchestrate avoidance and approach behavior

Gomez, J. A.; Perkins, J.; Beaudoin, G.; Cook, N.; Quraishi, S. A.; Szoeke, E.; Wanat, M. J.; Paladini, C. A.

10.1101/401919 — neuroscience — Posted on 2018-08-27

464 Detection of instability in 18S and 5.8S rDNA copy numbers and 18S:5.8S ratios in longitudinally-collected human DNA samples detected by monochrome multiplex qPCR

Ligerman, C. B.; Baird, L.; Leppert, M. F.; Cawthon, R. M.

10.1101/361840 — genomics — Posted on 2018-08-27

465 Persistent coding of outcome-predictive cue features in the rat nucleus accumbens

Gmaz, J. M.; Carmichael, J. E.; van der Meer, M.

10.1101/300251 — neuroscience — Posted on 2018-08-27

466 The Signaling Pathways Project: an integrated ‘omics knowledgebase for mammalian cellular signaling pathways

Ochsner, S.; Abraham, D.; Martin, K.; Ding, W.; McOwiti, A.; Wang, Z.; Andreano, K.; Hamilton, R.; Chen, Y.; Hamilton, A.; Gantner, M.; Dehart, M.; Qu, S.; Hilsenbeck, S.; Becnel, L.; Bridges, D.; Maayan, A.; Huss, J.; Stossi, F.; Foulds, C.; Kralli, A.; McDonnell, D.; McKenna, N.

10.1101/401729 — cell biology — Posted on 2018-08-27

467 FastqCleaner: an interactive Bioconductor application for quality-control, filtering and trimming of FASTQ files

Roser, L. G.; Aügero, F.; Sanchez, D.

10.1101/393140 — bioinformatics — Posted on 2018-08-27

468 The Mycobacterium tuberculosisphosphate-sensing Pst/SenX3-RegX3 system regulates ESX-5 secretion to evade host immunity

Elliott, S. R.; White, D. W.; Tischler, A. D.

10.1101/400960 — microbiology — Posted on 2018-08-27

469 Enabling tools for Toxoplasma glycobiology

Gas-Pascual, E.; Ichikawa, H. T.; Sheikh, M. O.; Serji, M. I.; Deng, B.; Mandalasi, M.; Bandini, G.; Samuelson, J.; Wells, L.; West, C. M.

10.1101/401828 — microbiology — Posted on 2018-08-27

470 The influence of X chromosome variants on trait neuroticism.

Luciano, M.; Davies, G.; Summers, K.; Hill, W. D.; Hayward, C.; Liewald, D.; Porteous, D. J.; Gale, C.; McIntosh, A. M.; Deary, I.

10.1101/401166 — genetics — Posted on 2018-08-27

471 Direct observation of rotation-coupled protein diffusion along DNA on the microsecond timescale

Marklund, E.; Amselem, E.; Kipper, K.; Zheng, X.; Johansson, M.; Deindl, S.; Elf, J.

10.1101/401414 — biophysics — Posted on 2018-08-27

472 Microsatellite primer development for invasive perennial herb, Gypsophila paniculata (Caryophyllaceae)

Leimbach-Maus, H. B.; Parks, S. R.; Partridge, C. G.

10.1101/401398 — plant biology — Posted on 2018-08-27

473 UNCROSS2: identification of cross-talk in 16S rRNA OTU tables

Edgar, R.

10.1101/400762 — bioinformatics — Posted on 2018-08-27

474 Where do animals covered by the US Animal Welfare Act live? Analysis of USDA licensed and registered entities

Bennett, A. J.; Schoenbeck, E. G.

10.1101/379412 — zoology — Posted on 2018-08-27

475 Hepatocyte-Specific Hepatocyte Nuclear Factor 4 alpha (HNF4α) Deletion Decreases Resting Energy Expenditure By Disrupting Lipid and Carbohydrate Homeostasis

Huck, I.; Morris, E. M.; Thyfault, J. P.; Apte, U.

10.1101/401802 — physiology — Posted on 2018-08-27

476 Reconstructing meaning from bits of information

Kivisaari, S. L.; van Vliet, M.; Hulten, A.; Lindh-Knuutila, T.; Faisal, A.; Salmelin, R.

10.1101/401380 — neuroscience — Posted on 2018-08-27

477 CLIP-Seq and massively parallel functional analysis of the CELF6 RNA binding protein reveals a role in destabilizing synaptic gene mRNAs through interaction with 3’UTR elements in vivo

Rieger, M. A.; King, D. M.; Cohen, B. A.; Dougherty, J. D.

10.1101/401604 — molecular biology — Posted on 2018-08-27

478 SABER enables highly multiplexed and amplified detection of DNA and RNA in cells and tissues

Kishi, J. Y.; Beliveau, B. J.; Lapan, S. W.; West, E. R.; Zhu, A.; Sasaki, H. M.; Saka, S. K.; Wang, Y.; Cepko, C. L.; Yin, P.

10.1101/401810 — genetics — Posted on 2018-08-27

479 A new phylogenetic protocol: Dealing with model misspecification and confirmation bias in molecular phylogenetics

Jermiin, L. S.; Catullo, R. A.; Holland, B. R.

10.1101/400648 — evolutionary biology — Posted on 2018-08-27

480 The Signaling Pathways Project: an integrated ‘omics knowledgebase for mammalian cellular signaling pathways

10.1101/401729 — bioinformatics — Posted on 2018-08-27

481 Inferring the molecular mechanisms of noncoding Alzheimer’s disease-associated genetic variants

Amlie-Wolf, A.; Tang, M.; Way, J.; Dombroski, B.; Jiang, M.; Vrettos, N.; Chou, Y.-F.; Zhao, Y.; Kuzma, A.; Mlynarski, E. E.; Leung, Y. Y.; Brown, C. D.; Wang, L.-S.; Schellenberg, G. D.

10.1101/401471 — bioinformatics — Posted on 2018-08-27

482 Haploinsufficiency of A20 impairs protein-protein interactome and leads into caspase-8-dependent enhancement of NLRP3 inflammasome activation

Rajamäki, K.; Keskitalo, S.; Seppänen, M.; Kuismin, O.; Vähäsalo, P.; Trotta, L.; Väänänen, A.; Glumoff, V.; Keskitalo, P.; Kaarteenaho, R.; Jartti, A.; Hautala, N.; Jackson, P.; Nordström, D. C.; Saarela, J.; Hautala, T.; Eklund, K. K.; Varjosalo, M.

10.1101/401034 — molecular biology — Posted on 2018-08-27

483 Differential amplicons for the evaluation of RNA integrity extracted from complex environmental samples

Cholet, F.; Ijaz, U. Z.; Smith, C. J.

10.1101/401109 — microbiology — Posted on 2018-08-27

484 Repurposing of drugs as novel influenza inhibitors from clinical gene expression infection signatures

Pizzorno, M. A.; Terrier, O.; Nicolas de Lamballerie, C.; Julien, T.; Padey, B.; Traversier, A.; Roche, M.; Hamelin, M.-E.; Rheaume, C.; Croze, S.; Escuret, V.; Poissy, J.; Lina, B.; Legras-Lachuer, C.; Textoris, J.; Boivin, G.; Rosa-Calatrava, M.

10.1101/401315 — microbiology — Posted on 2018-08-27

485 Antimicrobial, Antioxidant and Anti-Inflammatory Activities of Proteins of Phaseoulus lunatus (Fabaceae) Baby Lima Beans Produced in Ecuador

Tamayo, J.; Poveda, T.; Paredes, M.; Vasquez, G.; Calero-Caceres, W.

10.1101/401323 — microbiology — Posted on 2018-08-27

486 Evaluation of RNA-seq normalization methods using challenging datasets

Uebbing, S.

10.1101/401679 — genomics — Posted on 2018-08-27

487 Protect TUDCA stimulated CKD-derived hMSCs against the CKD-Ischemic disease via upregulation of PrPC

Yoon, Y. M.; Kim, S.; Han, Y.-S.; Yun, C. W.; Lee, J. H.; Noh, H.; Lee, S. H.

10.1101/401356 — cell biology — Posted on 2018-08-27

488 A unified model for microtubule rescue

Fees, C. P.; Moore, J.

10.1101/401372 — cell biology — Posted on 2018-08-27

489 A mutagenesis screen for essential plastid biogenesis genes in human malaria parasites

Tang, Y.; Meister, T. R.; Walczak, M.; Pulkoski-Gross, M.; Hari, S. B.; Sauer, R. T.; Amberg-Johnson, K.; Yeh, E.

10.1101/401570 — cell biology — Posted on 2018-08-27

490 The Desmosome is a Mesoscale Lipid Raft-Like Membrane Domain

Lewis, J. D.; Caldara, A. L.; Zimmer, S. E.; Seybold, A.; Strong, N. L.; Stahley, S. N.; Frangakis, A. S.; Levental, I.; Wahl, J. K.; Mattheyses, A. L.; Sasaki, T.; Nakabayashi, K.; Hata, K.; Matsubara, Y.; Ishida-Yamamoto, A.; Amagai, M.; Kubo, A.; Kowalczyk, A. P.

10.1101/401455 — cell biology — Posted on 2018-08-27

491 Detection of HPV16, HPV18, p16, and E6/E7 MRNA in Nasopharyngeal Cancer: A Systematic Review and Meta-Analysis

Tham, T.; Machado, R.; Khaymovich, J.; Costantino, P.

10.1101/401554 — cancer biology — Posted on 2018-08-27

492 Zinc Boosts EGCG’s hIAPP Amyloid Inhibition Both in Solution and Membrane

Lee, Y.-H.; Lin, Y.; Cox, S.; Kinoshita, M.; Sahoo, B.; Ivanova, M.; Ramamoorthy, A.

10.1101/401521 — biophysics — Posted on 2018-08-27

493 HTSlib-js: Developer toolkit for a client-side JavaScript interface for HTSlib

Park, J.; Childs, L. H.; Schlesner, M.; Eils, R.

10.1101/397935 — bioinformatics — Posted on 2018-08-27

494 Where did you come from, where did you go: Refining Metagenomic Analysis Tools for HGT characterisation

Seiler, E.; Trappe, K.; Renard, B. Y.

10.1101/401349 — bioinformatics — Posted on 2018-08-27

495 EVR: Reconstruction of Bacterial Chromosome 3D Structure Using Error-Vector Resultant Algorithm

Hua, K.-J.; Ma, B.-G.

10.1101/401513 — bioinformatics — Posted on 2018-08-27

496 A serial dilution method for assessment of microplastic toxicity in suspension

Gerdes, Z.; Hermann, M.; Ogonowski, M.; Gorokhova, E.

10.1101/401331 — pharmacology and toxicology — Posted on 2018-08-27

497 Real-time non-invasive intracranial state estimation using unscented Kalman filter

Ryu, S.; Park, C.; Jung, B.; Lee, S.; Hong, C.; Kim, Y.; Lee, B.

10.1101/400945 — neuroscience — Posted on 2018-08-27

498 Depletion of microbiome-derived molecules in the host using Clostridium genetics

Guo, C.-J.; Allen, B.; Hiam, K.; Dodd, D.; van Treuren, W.; Higginbottom, S.; Fischer, C.; Sonnenburg, J.; Spitzer, M.; Fischbach, M.

10.1101/401489 — microbiology — Posted on 2018-08-27

499 Sequencing of the MHC region defines HLA-DQA1 as the major independent risk for anti-citrullinated protein antibodies (ACPA)-positive rheumatoid arthritis in Han population

Guo, J.; Zhang, T.; Cao, H.; Li, X.; Liang, H.; Liu, M.; Zou, Y.; Zhang, Y.; Sun, X.; Hu, F.; Du, Y.; Mo, X.; Liu, X.; Yang, Y.; Yang, H.; Wu, X.; Zhang, X.; Jia, H.; Jiang, H.; Hou, Y.; Liu, X.; Su, Y.; Zhang, M.; Yang, H.; Wang, J.; Sun, L.; Liu, L.; Padyukov, L.; Lai, L.; Yamamoto, K.; Zhang, X.; Klareskog, L.; Xu, X.; Li, Z.

10.1101/400937 — genetics — Posted on 2018-08-27

500 Parasite-mediated anorexia increases or decreases virulence evolution, depending on dietary context

Hite, J. L.; Cressler, C. E.

10.1101/401760 — evolutionary biology — Posted on 2018-08-27

501 Automatic Removal of False Connections in Diffusion MRI Tractography Using Topology-Informed Pruning (TIP)

Yeh, F.-C.; Panesar, S.; Barrios, J.; Fernandes, D.; Abhinav, K.; Meola, A.; Fernandez-Miranda, J. C.

10.1101/338624 — neuroscience — Posted on 2018-08-27

502 DataRemix: a universal data transformation for optimal inference from gene expression datasets

Mao, W.; Hausler, R.; Chikina, M.

10.1101/357467 — genomics — Posted on 2018-08-27

503 Implementation of the Water Framework Directive: Lessons learned and future perspectives for an ecologically meaningful classification of the status of Greek lakes, Mediterranean region

Moustaka-Gouni, M.; Sommer, U.; Economou-Amilli, A.; Arhonditsis, G. B.; Katsiapi, M.; Papastergiadou, E.; Kormas, K. A.; Vardaka, E.; Karayanni, H.; Papadimitriou, T.

10.1101/371799 — ecology — Posted on 2018-08-27

504 Aurora B is required for programmed variations of cytokinesis during morphogenesis in the C. elegans embryo

Bai, X.; Lee, P.-Y.; Chen, C.-Y.; Simmons, J. R.; Nebenfuehr, B.; Mitchell, D.; Klebanow, L. R.; Mattson, N.; Sorensen Turpin, C. G.; Chen, B.-C.; Betzig, E.; Bembenek, J. N.

10.1101/319657 — cell biology — Posted on 2018-08-27

505 Reactivated spatial context guides episodic recall

Herweg, N. A.; Sharan, A. D.; Sperling, M. R.; Brandt, A.; Schulze-Bonhage, A.; Kahana, M. J.

10.1101/399972 — neuroscience — Posted on 2018-08-27

506 The Emotional Glue of the Senses: Affective Certainty and Congruency in the Rubber Hand Illusion

Filippetti, M. L.; Kirsch, L. P.; Crucianelli, L.; Fotopoulou, A.

10.1101/401422 — neuroscience — Posted on 2018-08-27

507 Spatial neuronal synchronization and the waveform of oscillations: implications for EEG and MEG

Schaworonkow, N.; Nikulin, V. V.

10.1101/401091 — neuroscience — Posted on 2018-08-27

508 A practical generation interval-based approach to inferring the strength of epidemics from their speed

Park, S. W.; Champredon, D.; Weitz, J.; Dushoff, J.

10.1101/312397 — epidemiology — Posted on 2018-08-27

509 Infection dynamics in L. major autophagic machinery is regulated by ATG9-PI3P negative feedback loop

Kosey, D.; Soni, B.; Nimsarkar, P.; Singh, S.

10.1101/398545 — systems biology — Posted on 2018-08-27

510 The role of land use types and water chemical properties in structuring the microbiome of a connected lakes system

Marmen, S.; Blank, L.; Al-Ashhab, A.; Malik, A.; Ganzert, L.; Lalzar, M.; Grossart, H.-P.; Sher, D.

10.1101/401299 — microbiology — Posted on 2018-08-27

511 Education, intelligence and Alzheimer’s disease: Evidence from a multivariable two-sample Mendelian randomization study

Anderson, E. L.; Howe, L. D.; Wade, K. H.; Ben-Shlomo, Y.; Hill, W. D.; Deary, I. J.; Sanderson, E. C.; Zheng, J.; Korologou-Linden, R.; Stergiakouli, E.; Davey Smith, G.; Davies, N. M.; Hemani, G.

10.1101/401042 — genetics — Posted on 2018-08-27

512 Developing an automated iterative near-term forecasting system for an ecological study

White, E. P.; Yenni, G. M.; Taylor, S. D.; Christensen, E. M.; Bledsoe, E. K.; Simonis, J. L.; Ernest, S. K. M.

10.1101/268623 — ecology — Posted on 2018-08-27

513 Polarity signaling ensures epidermal homeostasis by coupling cellular mechanics and genomic integrity

Dias Gomes, M.; Letzian, S.; Saynisch, M.; Iden, S.

10.1101/401562 — cell biology — Posted on 2018-08-27

514 Centromere repositioning induced by inner kinetochore impairment generates a meiosis barrier

Lu, M.; He, X.

10.1101/401257 — cell biology — Posted on 2018-08-27

515 Quantifying the fitness of tissue-specific evolutionary trajectories by harnessing cancer’s repeatability at the genetic level

Tokutomi, N.; Moyret-Lalle, C.; PUISIEUX, A.; Sugano, S.; Martinez, P.

10.1101/401059 — cancer biology — Posted on 2018-08-27

516 Cationic polymethacrylate-copolymer acts as an agonist for beta-amyloid and antagonist for amylin fibrillation

Sahoo, B.; Genjo, T.; Stoddard, A.; Yasuhara, K.; Fierke, C. A.; Ramamoorthy, A.

10.1101/401687 — biophysics — Posted on 2018-08-27

517 Learning dynamical information from static protein and sequencing data

Pearce, P.; Woodhouse, F. G.; Forrow, A.; Kelly, A.; Kusumaatmaja, H.; Dunkel, J.

10.1101/401067 — bioinformatics — Posted on 2018-08-27

518 Exploring Single-Cell Data with Deep Multitasking Neural Networks

Amodio, M.; van Dijk, D.; Srinivasan, K.; Chen, W. S.; Mohsen, H.; Moon, K. R.; Campbell, A.; Zhao, Y.; Wang, X.; Venkataswamy, M.; Desai, A.; V., R.; Kumar, P.; Montgomery, R.; Wolf, G.; Krishnaswamy, S.

10.1101/237065 — bioinformatics — Posted on 2018-08-27

519 Rapid prototyping of a multilayer microphysiological system for primary human intestinal epithelial culture

Hosic, S.; Puzan, M. L.; Lake, W.; Zhou, F.; Koppes, R. A.; Breault, D. T.; Murthy, S. K.; Koppes, A. N.

10.1101/400721 — bioengineering — Posted on 2018-08-27

520 The context-dependent nature of the neural implementation of intentions

Uithol, S.; Goergen, K.; Pischedda, D.; Toni, I.; Haynes, J.-D.

10.1101/401174 — neuroscience — Posted on 2018-08-27

521 Fungal growth is affected by and affects pH and redox potential (Eh) of the growth medium

Bousset, L.; Ermel, M.; Soglonou, B.; Husson, O.

10.1101/401182 — microbiology — Posted on 2018-08-27

522 A probable genetic origin for pit defects on the molars of Paranthropus robustus

Towle, I.; Irish, J. D.

10.1101/400671 — evolutionary biology — Posted on 2018-08-27

523 Visual intensity ratio modulates operant learning responses in larval zebrafish

Yang, W.; Meng, Y.; Li, D.; Wen, Q.

10.1101/401000 — animal behavior and cognition — Posted on 2018-08-27

524 Isolated individuals and groups show opposite preferences toward humidity

Calvo Martin, M.; Nicolis, S. C.; Planas-Sitja, I.; de Biseau, J.-C.; Deneubourg, J.-L.

10.1101/398651 — animal behavior and cognition — Posted on 2018-08-27

525 Multichannel Silicon Probes for Laminar Cortical and Hippocampal Recordings in Large Animals.

Ulyanova, A. V.; Adam, C. D.; Koch, P. F.; Gagnon, K. G.; Grovola, M. R.; Cullen, D. K.; Chen, H. I.; Holtzmann, T.; Jameison, B.; Wolf, J. A.

10.1101/400812 — neuroscience — Posted on 2018-08-27

526 Modulation of the spontaneous hemodynamic response function across levels of consciousness

Wu, G.-R.; Di Perri, C.; Charland-Verville, V.; Martial, C.; Laureys, S.; Marinazzo, D.

10.1101/401547 — neuroscience — Posted on 2018-08-27

527 Engineered transfer RNAs for suppression of premature termination codons

Lueck, J. D.; Yoon, J. S.; Perales-Puchalt, A.; Mackey, A. L.; Infield, D. T.; Behlke, M. A.; Pope, M. R.; Weiner, D. B.; Skach, W. R.; McCray, P. B.; Ahern, C. A.

10.1101/400127 — molecular biology — Posted on 2018-08-27

528 Female-biased embryonic death from genomic instability-induced inflammation

McNairn, A. J.; Chuang, C.-H.; Bloom, J. C.; Wallace, M. D.; Schimenti, J. C.

10.1101/400820 — genetics — Posted on 2018-08-27

529 Label-free digital holographic microscopy reveals virus-induced cytopathic effects in live cells

Yakimovich, A.; Witte, R.; Andriasyan, V.; Georgi, F.; Greber, U.

10.1101/401075 — cell biology — Posted on 2018-08-27

530 Topokaryotyping demonstrates single cell variability and stress dependent variations in nuclear envelope associated domains

Jurisic, A.; Robin, C.; Tarlykov, P.; Siggens, L.; Schoell, B.; Jauch, A.; Ekwall, K.; Sorensen, C. S.; Lipinski, M.; Shoaib, M.; Ogryzko, V.

10.1101/401539 — cell biology — Posted on 2018-08-27

531 Aurora A inhibition limits centrosome clustering and promotes mitotic catastrophe in cells with supernumerary centrosomes

Navarro-Serer, B.; Childers, E. P.; Hermance, N. M.; Mercadante, D.; Manning, A. L.

10.1101/401661 — cancer biology — Posted on 2018-08-27

532 e-workflow for recording of glycomic mass spectrometric data in compliance with reporting guidelines

Rojas-Macias, M. A.; Mariethoz, J.; Andersson, P.; Jin, C.; Venkatakrishnan, V.; Aoki, N. P.; Shinmachi, D.; Ashwood, C.; Madunic, K.; Zhang, T.; Miller, R. L.; Horlacher, O.; Struwe, W. B.; Levander, F.; Kolarich, D.; Rudd, P. M.; Wuhrer, M.; Kettner, C.; Packer, N. H.; Aoki-Kinoshita, K. F.; Lisacek, F.; Karlsson, N.

10.1101/401141 — bioinformatics — Posted on 2018-08-27

533 Molecular mimicry in deoxy-nucleotide catalysis: the structure of Escherichia coli dGTPase reveals the molecular basis of dGTP selectivity

Barnes, C. O.; Wu, Y.; Song, J.; Lin, G.; Baxter, E. L.; Brewster, A. S.; Nagarajan, V.; Holmes, A.; Soltis, M.; Gronenborn, A.; Ahn, J.; Cohen, A. E.; Calero, G.

10.1101/385401 — biophysics — Posted on 2018-08-27

534 Interferometric scattering microscopy reveals microsecond nanoscopic protein motion on a live cell membrane

Taylor, R. W.; Gholami Mahmoodabadi, R.; Rauschenberger, V.; Giessl, A.; Schambony, A.; Sandoghdar, V.

10.1101/401133 — biophysics — Posted on 2018-08-27

535 Range size dynamics can explain why evolutionarily age and diversification rate correlate with contemporary extinction risk in plants

Tanentzap, A. J.; Igea, J.; Johnston, M. G.; Larcombe, M. J.

10.1101/152215 — evolutionary biology — Posted on 2018-08-27

536 The cost of enforcing a marine protected area to achieve ecological targets for the recovery of fish biomass

Brown, C.; Parker, B.; Ahmadia, G. N.; Ardiwijaya, R.; Purwanto, P.; Game, E. T.

10.1101/216598 — ecology — Posted on 2018-08-27

537 Exploring Single-Cell Data with Deep Multitasking Neural Networks

10.1101/237065 — bioinformatics — Posted on 2018-08-27

538 The interplay of synaptic plasticity and scaling enables the self-organized allocation of multiple memory representations

Auth, J. M.; Nachstedt, T.; Tetzlaff, C.

10.1101/260950 — neuroscience — Posted on 2018-08-27

539 Neo-formation of chromosomes in bacteria

Poirion, O. B.; Lafay, B.

10.1101/264945 — genomics — Posted on 2018-08-27

540 Integrative Cross-species Analyses Suggest Deficits in Habituation Learning as a Widely Affected Mechanism in Intellectual Disability and Autism Spectrum Disorders

Fenckova, M.; Asztalos, L.; Cizek, P.; Singgih, E. L.; Blok, L. E. R.; Glennon, J. C.; IntHout, J.; Zweier, C.; Eichler, E. E.; Bernier, R.; Asztalos, Z.; Schenck, A.

10.1101/285981 — neuroscience — Posted on 2018-08-27

541 Molecular Strategy for Blocking Isopeptide Bond Formation in Nascent Pilin Proteins

Rivas-Pardo, J. A.; Tapia-Rojo, R.; Badilla, C. L.; Alonso Caballero, A.; Fernandez, J. M.

10.1101/310227 — biophysics — Posted on 2018-08-27

542 Using the Weibull accelerated failure time regression model to predict time to health events

Liu, E.; Lim, K.

10.1101/362186 — epidemiology — Posted on 2018-08-27

543 Seeing versus Knowing: The Temporal Dynamics of Real and Implied Colour Processing in the Human Brain

Teichmann, L.; Grootswagers, T.; Carlson, T.; Rich, A.

10.1101/369926 — neuroscience — Posted on 2018-08-27

544 The crossover function of MutSγ is activated via Cdc7-dependent stabilization of Msh4

He, W.; Rao, H. B. D. P.; Tang, S.; Bhagwat, N.; Kulkarni, D.; Ma, Y.; Chang, M. A. W.; Hall, C.; Wang, J.; Manacsa, H. S.; Baker, C.; Verhees, G. F.; Singh, L.; Chen, X.; Hollingsworth, N. M.; Cejka, P.; Hunter, N.

10.1101/386458 — genetics — Posted on 2018-08-27

545 SciPipe - A workflow library for agile development of complex and dynamic bioinformatics pipelines

Lampa, S.; Dahlö, M.; Alvarsson, J.; Spjuth, O.

10.1101/380808 — bioinformatics — Posted on 2018-08-27

546 A note on stochastic modeling of biological systems: automatic generation of an optimized Gillespie algorithm

Vanhaelen, Q.

10.1101/395392 — systems biology — Posted on 2018-08-27

547 Abnormalities of placental development and function are associated with the different fetal growth patterns of hypoplastic left heart syndrome and transposition of the great arteries.

Troja, W.; Owens, K. J.; Courtney, J.; Hinton, A. C.; Hinton, R. B.; Cnota, J. F.; Jones, H. N.

10.1101/388074 — physiology — Posted on 2018-08-27

548 HDAC Inhibitors Rescue Multiple Disease-Causing CFTR Variants

Angles, F.; Hutt, D.; Balch, W. E.

10.1101/399451 — cell biology — Posted on 2018-08-27

549 DEBrowser: Interactive Differential Expression Analysis and Visualization Tool for Count Data

Kucukural, A.; Yukselen, O.; Ozata, D. M.; Moore, M. J.; Garber, M.

10.1101/399931 — bioinformatics — Posted on 2018-08-27

550 Bcl-xL inhibition enhances Dinaciclib-induced cell death in soft-tissue sarcomas.

Rello-Varona, S.; Fuentes-Guirado, M.; Lopez-Alemany, R.; Contreras-Perez, A.; Mulet-Margalef, N.; Garcia-Monclus, S.; Tirado, O. M.; Garcia del Muro, X.

10.1101/400986 — cancer biology — Posted on 2018-08-27

551 Human pancreatic islet 3D chromatin architecture provides insights into the genetics of type 2 diabetes

Miguel-Escalada, I.; Bonas-Guarch, S.; Cebola, I.; Ponsa-Cobas, J.; Mendieta-Esteban, J.; Rolando, D. M. Y.; Javierre, B. M.; Atla, G.; Farabella, I.; Morgan, C. C.; Garcia-Hurtado, J.; Beucher, A.; Moran, I.; Pasquali, L.; Ramos, M.; Appel, E. V. R.; Linneberg, A.; Gjesing, A. P.; Witte, D. R.; Pedersen, O.; Garup, N.; Ravassard, P.; Torrents, D.; Mercader, J. M.; Piemonti, L.; Berney, T.; de Koning, E. J. P.; Kerr-Conte, J.; Pattou, F.; Fedko, I. O.; Prokopenko, I.; Hansen, T.; Marti-Renom, M. A.; Fraser, P.; Ferrer, J.

10.1101/400291 — genomics — Posted on 2018-08-27

552 Cyclodextrin triggers MCOLN1-dependent endo-lysosome secretion in Niemann-Pick type C cells

Vacca, F.; Vossio, S.; Mercier, V.; Moreau, D.; Johnson, S.; Paz Montoya, J.; Moniatte, M.; Gruenberg, J.

10.1101/401190 — cell biology — Posted on 2018-08-27

553 Evaluation of tuberculosis treatment response with serial C-reactive protein measurements

Wilson, D.; Moosa, M.-Y. S.; Cohen, T.; Cudahy, P. G. T.; Aldous, C.; Maartens, G.

10.1101/400572 — microbiology — Posted on 2018-08-27

554 Reverse engineering of an aspirin-responsive regulator in bacteria

Monteiro, L. M. O.; Arruda, L. M.; Medeiros, A. S.; Martins-Santana, L.; Alves, L. d. F.; Guazzaroni, M.-E.; de Lorenzo, V.; Silva-Rocha, R.

10.1101/400788 — synthetic biology — Posted on 2018-08-27

555 A simple cloning-free method to efficiently induce gene expression using CRISPR/Cas9

Fang, L.; Hung, S. S. C.; Yek, J.; Nguyen, T.; Khan, S.; Hewitt, A. W.; Wong, R. C. B.

10.1101/400838 — molecular biology — Posted on 2018-08-27

556 BDNF/TrkB signaling in pancreatic islet beta cells

Kalwat, M. A.; Huang, Z.; McGlynn, K.; Cobb, M.

10.1101/400010 — cell biology — Posted on 2018-08-27

557 Pirfenidone attenuates lung fibrotic fibroblast-mediated fibrotic responses to transforming growth factor-β1

Jin, J.; Togo, S.; Kadoya, K.; tulafu, m.; Namba, Y.; Moe Iwai, M.; Watanabe, J.; Nagahama, K.; Okabe, T.; Hidayat, M.; Kodama, Y.; Kitamura, H.; Ogura, T.; Kitamura, N.; Ikeo, K.; Sasaki, S.; Tominaga, S.; Takahashi, K.

10.1101/400978 — cell biology — Posted on 2018-08-27

558 DSCAM-AS1 promotes tumor growth of breast cancer by reducing miR-204-5p and upregulating RRM2

Liang, W.-H.; Li, N.; Yuan, Z.-Q.; Qian, X.-L.; Wang, Z.-H.

10.1101/400994 — biochemistry — Posted on 2018-08-27

559 Global expansion and redistribution of Aedes-borne virus transmission risk with climate change

Ryan, S. J.; Carlson, C. J.; Mordecai, E. A.; Johnson, L. R.

10.1101/172221 — epidemiology — Posted on 2018-08-26

560 Electrophysiological Signature Reveals Laminar Structure of the Porcine Hippocampus

Ulyanova, A. V.; Koch, P. F.; Cottone, C.; Grovola, M. R.; Browne, K. D.; Russo, R. J.; Adam, C. D.; Smith, D. H.; Chen, H. I.; Johnson, V. E.; Cullen, D. K.; Wolf, J. A.

10.1101/201285 — neuroscience — Posted on 2018-08-26

561 PARylation regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins

Duan, Y.; Du, A.; Gu, J.; Duan, G.; Wang, C.; Ma, Z.; Sun, L.; Qian, B.; Deng, X.; Zhang, K.; Tian, K.; Zhang, Y.; Jiang, H.; Liu, C.; Fang, Y.

10.1101/396465 — neuroscience — Posted on 2018-08-26

562 Tbx1 regulates extracellular matrix-cell interactions in the second heart field.

Alfano, D.; Altomonte, A.; Cortes, C.; Bilio, M.; Kelly, R. G.; Baldini, A.

10.1101/267906 — developmental biology — Posted on 2018-08-26

563 Experimental evidence that female rhesus macaques (Macaca mulatta) perceive variation in male facial masculinity

Rosenfield, K. A.; Semple, S.; Georgiev, A. V.; Maestripieri, D.; Higham, J. P.; Dubuc, C.

10.1101/222810 — animal behavior and cognition — Posted on 2018-08-26

564 The RNA helicase UPF1 associates with mRNAs co-transcriptionally and is required for the release of mRNAs from transcription sites

Singh, A. K.; Choudhury, S. R.; De, S.; Zhang, J.; Kissane, S.; Dwivedi, V.; Ramanathan, P.; Orsini, L.; Hebenstreit, D.; Brogna, S.

10.1101/395863 — cell biology — Posted on 2018-08-26

565 Neural circuit basis of aversive odour processing in Drosophila from sensory input to descending output.

Huoviala, P.; Dolan, M.-J.; Love, F.; Frechter, S.; Roberts, R. J. V.; Mitrevica, Z.; Schlegel, P.; Bates, A. S. S.; Aso, Y.; Rodrigues, T.; Cornwall, H.; Stensmyr, M.; Bock, D.; Rubin, G. M.; Costa, M.; Jefferis, G. S. X. E.

10.1101/394403 — neuroscience — Posted on 2018-08-26

566 Linking Fungal and Bacterial Proliferation to Microbiologically Influenced Corrosion in B20 Biodiesel Storage Tanks

Stamps, B. W.; Bojanowski, C. L.; Drake, C. A.; Nunn, H. S.; Lloyd, P. F.; Floyd, J. G.; Berberich, K. A.; Neal, A. R.; Crookes-Goodson, W. J.; Stevenson, B. S.

10.1101/399428 — microbiology — Posted on 2018-08-26

567 A biophysical model of molecular clusters: interplay of multivalency, membrane localization, steric hindrance, molecular flexibility and intracellular crowding

Chattaraj, A.; Youngstrom, M.; Loew, L. M.

10.1101/373084 — biophysics — Posted on 2018-08-26

568 bayNorm: Bayesian gene expression recovery, imputation and normalisation for single cell RNA-sequencing data

Tang, W.; Bertaux, F.; Thomas, P.; Stefanelli, C.; Saint, M.; Marguerat, S. B.; Shahrezaei, V.

10.1101/384586 — bioinformatics — Posted on 2018-08-26

569 A 3D model of human skeletal muscle innervated with stem cell-derived motor neurons enables epsilon-subunit targeted myasthenic syndrome studies

Afshar Bakooshli, M.; Lippmann, E. S.; Mulcahy, B.; Iyer, N.; Nguyen, C. T.; Tung, K.; Stewart, B. A.; Bigot, A.; Pegoraro, E.; Ahn, H.; Ginsberg, H.; Zhen, M.; Ashton, R. S.; Gilbert, P. M.

10.1101/275545 — bioengineering — Posted on 2018-08-26

570 Environmental programming of adult foraging behavior in C. elegans

Pradhan, S.; Quilez, S.; Homer, K.; Hendricks, M.

10.1101/400754 — neuroscience — Posted on 2018-08-26

571 Mate-pair Library Construction with Controlled Polymerization Enables Comprehensive Structural Rearrangement Detection

Zirui, D.; Xia, Z.; Qiaoling, L.; Zhenjun, Y.; Yang, X.; Andrei, A.; Hanjie, S.; Ou, W.; Jie, R.; Han, R.; Hanmin, W.; Xiaojuan, Q.; Jiguang, L.; Xiaofan, Z.; Dai, P.; Kong, X.; Oleg, A.; Shane, G.; Jennifer, Y.; Bahram G., K.; Killeen, K.; Chao, D.; Pengjuan, L.; Zilan, M.; Wenwei, Z.; Xun, X.; Radoje, D.; Kwong Wai, C.; Yuan, J.

10.1101/400689 — genomics — Posted on 2018-08-26

572 Evolution of mating types in finite populations: the precarious advantage of being rare

Czuppon, P.; Rogers, D. W.

10.1101/400598 — evolutionary biology — Posted on 2018-08-26

573 A new insight into underlying disease mechanism through semi-parametric latent differential network model

He, Y.; Ji, J.; Xie, L.; Zhang, X.; Xue, F.

10.1101/397265 — bioinformatics — Posted on 2018-08-26

574 Aggregation rule in animal collectives dynamically changes between majority and minority influence

Heras, F. J. H.; Romero-Ferrero, F.; Hinz, R. C.; de Polavieja, G. G.

10.1101/400747 — animal behavior and cognition — Posted on 2018-08-26

575 LittleBrain: a gradient-based tool for the topographical interpretation of cerebellar neuroimaging findings

Guell, X.; Goncalves, M.; Kaczmarzyk, J. R.; Gabrieli, J. D.; Schmahmann, J. D.; Ghosh, S. S.

10.1101/400416 — neuroscience — Posted on 2018-08-26

576 Goalkeeper game: a new assessment instrument in neurology showed higher predictive power than moca for gait performance in people with parkinson’s disease

Stern, R. B.; d'Alencar, M.; Uscapi, Y. L.; Gubitoso, M. D.; Roque, A. C.; Helene, A. F.; Piemonte, M. E. P.

10.1101/400457 — neuroscience — Posted on 2018-08-26

577 Characterization for Drought Tolerance and Physiological Efficiency in Novel Cytoplasmic Male Sterile Sources of Sunflower (Helianthus annuus L.)

Tyagi, V.; Kaur, G.; Kaushik, P.; Dhillon, S. K.

10.1101/400531 — genetics — Posted on 2018-08-26

578 Why do phylogenomic analyses of early animal evolution continue to disagree? Sites in different structural environments yield different answers

Pandey, A.; Braun, E. L.

10.1101/400465 — evolutionary biology — Posted on 2018-08-26

579 Genomic signatures accompanying the dietary shift to phytophagy in polyphagous beetles

Seppey, M.; Ioannidis, P.; Emerson, B. C.; Pitteloud, C.; Robinson-Rechavi, M.; Roux, J.; Escalona, H. E.; McKenna, D. D.; Misof, B.; Shin, S.; Zhou, X.; Waterhouse, R. M.; Alvarez, N.

10.1101/399808 — evolutionary biology — Posted on 2018-08-26

580 The dimensions of species diversity

Larcombe, M. J.; Jordan, G.; Bryant, D. J.; Higgins, S.

10.1101/400481 — evolutionary biology — Posted on 2018-08-26

581 Translocation and duplication from CRISPR-Cas9 editing in Arabidopsis thaliana

Lynagh, P. G.; Inagaki, S.; Amundson, K. R.; Marimithu, M. P. A.; Pike, B. R.; Henry, I. M.; Tan, E. H.; Comai, L.

10.1101/400507 — genetics — Posted on 2018-08-26

582 High resolution evolutionary analysis of within-host hepatitis C virus infection

Raghwani, J.; Wu, C.-H.; Ho, C. K.; Molenkamp, R.; Schinkel, J.; Pybus, O. G.; Lythgoe, K. A.

10.1101/400283 — evolutionary biology — Posted on 2018-08-26

583 Mechanisms of a locally adaptive shift in allocation among growth, reproduction, and herbivore resistance in Mimulus guttatus

Lowry, D.; Popovic, D.; Brennan, D. J.; Holeski, L. M.

10.1101/400523 — evolutionary biology — Posted on 2018-08-26

584 Dual role for fungal-specific outer kinetochore proteins during cell cycle and development in Magnaporthe oryzae

Shah, H.; Rawat, K.; Ashar, H.; Patkar, R.; Manjrekar, J.

10.1101/400549 — cell biology — Posted on 2018-08-26

585 LOTUS: a Single- and Multitask Machine Learning Algorithm for the Prediction of Cancer Driver Genes

Collier, O.; Stoven, V.; Vert, J.-P.

10.1101/398537 — bioinformatics — Posted on 2018-08-26

586 Topological data analysis quantifies biological nano-structure from single molecule localization microscopy

Pike, J. A.; Khan, A. O.; Pallini, C.; Thomas, S. G.; Mund, M.; Ries, J.; Poulter, N. S.; Styles, I. B.

10.1101/400275 — bioinformatics — Posted on 2018-08-26

587 ENRICH: a fast method to improve the quality of flexible macromolecular reconstructions

Kazemi, M.; Sorzano, C. O. S.; Des Georges, A.; Carazo, J. M.; Vargas, J.

10.1101/400317 — bioengineering — Posted on 2018-08-26

588 Development of the P300 from childhood to adulthood: a multimodal EEG and MRI study

Overbye, K.; Huster, R. J.; Walhovd, K. B.; Fjell, A. M.; Tamnes, C. K.

10.1101/304832 — neuroscience — Posted on 2018-08-25

589 Transcriptomic and functional analysis of the oosome, a unique form of germ plasm in the wasp Nasonia vitripennis

Quan, H.; Lynch, J. A.

10.1101/384032 — developmental biology — Posted on 2018-08-25

590 Scaling of G1 duration with population doubling time by a cyclin in Saccharomyces cerevisiae

Blank, H. M.; Callahan, M.; Pistikopoulos, I. P. E.; Polymenis, A. O.; Polymenis, M.

10.1101/240713 — cell biology — Posted on 2018-08-25

591 Complex genetic and epigenetic regulation deviates gene expression from a unifying global transcriptional program

Chagoyen, M.; Poyatos, J. F.

10.1101/390419 — systems biology — Posted on 2018-08-25

592 Biologically realistic mean-field models of conductance-based networks of spiking neurons with adaptation

di Volo, M.; Romagnoni, A.; Capone, C.; Destexhe, A.

10.1101/352393 — neuroscience — Posted on 2018-08-25

593 Analysis of novel domain-specific mutations in the zebrafish ndr2/cyclops gene generated using CRISPR-Cas9 RNPs

Turner, A. N.; Andersen, R. S.; Bookout, I. E.; Brashear, L. N.; Davis, J. C.; Gahan, D. M.; Gotham, J. P.; Hijaz, B. A.; Kaushik, A. S.; McGill, J. B.; Miller, V. L.; Moseley, Z. P.; Nowell, C. L.; Patel, R. K.; Rodgers, M. C.; Shihab, Y. A.; Walker, A. P.; Glover, S. R.; Foster, S. D.; Challa, A. K.

10.1101/277715 — genetics — Posted on 2018-08-25

594 Compensatory mechanisms render Tcf7l1a dispensable for eye formation despite its requirement in eye field specification

Young, R. M.; Cavodeassi, F.; Hawkins, T. A.; Stickney, H. L.; Schwarz, Q.; Lawrence, L. M.; Wierzbicki, C.; Gestri, G.; Ambrosio, E. M.; Klosner, A.; Rowell, J.; Bianco, I. H.; Allende, M. L.; Wilson, S. W.

10.1101/377119 — developmental biology — Posted on 2018-08-25

595 Signatures of negative frequency dependent selection in colonisation factors and the evolution of a multi-drug resistant lineage of Escherichia coli

McNally, A.; Kallonen, T.; Connor, C.; Abudahab, K.; Aanensen, D.; Horner, C.; Peacock, S.; Parkhill, J.; Croucher, N.; Corander, J.

10.1101/400374 — microbiology — Posted on 2018-08-25

596 IPSE, a parasite-derived host immunomodulatory protein, is a promising therapeutic for hemorrhagic cystitis

Zee, R.; Mbanefo, E. C.; Le, L.; Pennington, L.; Odegaard, J.; Jardetzky, T.; Alouffi, A.; Akinwale, J.; Falcone, F.; Hsieh, M.

10.1101/400424 — immunology — Posted on 2018-08-25

597 Heat Shock Factor 1 Dynamically Restructures the Yeast Genome

Chowdhary, S.; Kainth, A. S.; Gross, D. S.

10.1101/400499 — genetics — Posted on 2018-08-25

598 The deadly touch: protein denaturation at the water-air interface and how to prevent it

D'Imprima, E.; Floris, D.; Joppe, M.; Sanchez, R.; Grininger, M.; Kühlbrandt, W.

10.1101/400432 — biophysics — Posted on 2018-08-25

599 Mutations generated by repair of Cas9-induced double strand breaks are predictable from surrounding sequence

Allen, F. R.; Crepaldi, L. R.; Alsinet-Armengol, C.; Strong, A.; Kleshchevnikov, V.; De Angeli, P.; Palenikova, P.; Kosicki, M.; Bassett, A. R.; Harding, H.; Galanty, Y.; Munoz Martinez, F.; Metzakopian, E.; Jackson, S. P.; Parts, L.

10.1101/400341 — cell biology — Posted on 2018-08-25

600 The N-end Rule Pathway and Ubr1 enforces the compartmentalization of mitochodrial and secretory proteins through the recognition of P2-encoded cellular location signals

Tran, A.

10.1101/392373 — cell biology — Posted on 2018-08-25

601 Local membrane charge regulates β2 adrenergic receptor coupling to Gi

Strohman, M. J.; Maeda, S.; Hilger, D.; Masureel, M.; Du, Y.; Kobilka, B. K.

10.1101/400408 — biochemistry — Posted on 2018-08-25

602 Habitat complexity and benthic predator-prey interactions in Chesapeake Bay

Glaspie, C. N.; Seitz, R. D.

10.1101/224089 — ecology — Posted on 2018-08-25

603 The RNA helicase UPF1 associates with mRNAs co-transcriptionally and is required for the release of mRNAs from transcription sites

Singh, A. K.; Choudhury, S. R.; De, S.; Zhang, J.; Kissane, S.; Dwivedi, V.; Ramanathan, P.; Orsini, L.; Hebenstreit, D.; Brogna, S.

10.1101/395863 — cell biology — Posted on 2018-08-25

604 Evidence for the Modulation of the Immune Response in Peripheral Blood Mononuclear Cells after Stimulation with a High Molecular Weight β-glucan Isolated from Lactobacillus fermentum Lf2

Laws, A.; Vitlic, A.; Sadiq, S.; Ahmed, H. I.; Ale, E. C.; Binetti, A. G.; Collett, A.; Humphreys, P.

10.1101/400267 — microbiology — Posted on 2018-08-25

605 May the phage be with you? Prophage-like elements in the genomes of Soft Rot Pectobacteriaceae (Pectobacterium spp. and Dickeya spp.)

Czajkowski, R.

10.1101/399675 — microbiology — Posted on 2018-08-25

606 Evolution of DNA methylation in Papio baboons

Vilgalys, T. P.; Rogers, J.; Jolly, C.; Baboon Genome Analysis Consortium, ; Mukherjee, S.; Tung, J.

10.1101/400093 — genomics — Posted on 2018-08-25

607 BEES: Bayesian Ensemble Estimation from SAS, a SASSIE-web Module

Bowerman, S.; Curtis, J. E.; Clayton, J.; Brookes, E. H.; Weresczczynski, J.

10.1101/400168 — biophysics — Posted on 2018-08-25

608 DNMT inhibitors increase methylation of CpGs related to p53 pathway genes in colon, lymphoma, bladder, ovarian, and breast cancer cells

Aittokallio, T.; Giri, A. K.

10.1101/395467 — pharmacology and toxicology — Posted on 2018-08-25

609 Simulation of enteric colonisation by and screening for Carbapenemase Producing Enterobacteriaceae using an in-vitro human gut model.

Rooney, C. M.; Clark, E.; Davies, K.; Wilcox, M. H.; Chilton, C. H.

10.1101/399170 — microbiology — Posted on 2018-08-25

610 nsearch: An open source C++ library for processing and similarity searching of next-generation sequencing data

Schmid, S.; Julian, T.; Tamminen, M.

10.1101/399782 — bioinformatics — Posted on 2018-08-25

611 Stress alters social behavior and sensitivity to pharmacological activation of kappa opioid receptors in an age-specific manner in Sprague Dawley rats

Varlinskaya, E. I.; Spear, L. P.; Diaz, M.

10.1101/399758 — neuroscience — Posted on 2018-08-25

612 Frequency-specific brain dynamics related to prediction during language comprehension

Armeni, K.; Willems, R. M.; van den Bosch, A.; Schoffelen, J.-M.

10.1101/399733 — neuroscience — Posted on 2018-08-25

613 Identification of a cis-acting determinant limiting expression of sphingomyelinase gene sph2 in Leptospira interrogans with a gfp reporter plasmid

Matsunaga, J.; Haake, D. A.

10.1101/400259 — microbiology — Posted on 2018-08-25

614 Whole genome sequencing reveals high complexity of copy number variation at insecticide resistance loci in malaria mosquitoes

Lucas, E. R.; Miles, A.; Harding, N. J.; Clarkson, C. S.; Lawniczak, M. K. N.; Kwiatkowski, D. P.; Weetman, D.; Donnelly, M. J.; The Anopheles gambiae 1000 Genomes Consortium,

10.1101/399568 — evolutionary biology — Posted on 2018-08-25

615 A Bayesian Approach to Restricted Latent Class Models for Scientifically-Structured Clustering of Multivariate Binary Outcomes

Wu, Z.; Casciola-Rosen, L.; Rosen, A.; Zeger, S. L.

10.1101/400192 — bioinformatics — Posted on 2018-08-25

616 Assessing 16S marker gene survey data analysis methods using mixtures of human stool sample DNA extracts.

Olson, N. D.; Kumar, M. S.; Li, S.; Hao, S.; Timp, W.; Salit, M. L.; Stine, O. C.; Corrada Bravo, H.

10.1101/400226 — bioinformatics — Posted on 2018-08-25

617 Widespread formation of methane by Cyanobacteria in aquatic and terrestrial environments

Bizic-Ionescu, M.; Klintzch, T.; Ionescu, D.; Hindiyeh, M. Y.; Guenthel, M.; Muro Pastor, A. M.; Keppler, F.; Grossart, H.-P.

10.1101/398958 — microbiology — Posted on 2018-08-25

618 A heterogeneous spatial model in which savanna and forest coexist in a stable equilibrium

Durrett, R.; Ma, R.

10.1101/400051 — ecology — Posted on 2018-08-25

619 Effects of green seaweed extract on Arabidopsis early development suggest roles for hormone signalling in plant responses to algal fertilisers

Ghaderiardakani, F.; Collas, E.; Kohn Damiano, D.; Tagg, K.; Graham, N. S.; Coates, J.

10.1101/400143 — plant biology — Posted on 2018-08-25

620 SPECIES-SPECIFIC ROOT MICROBIOTA DYNAMICS IN RESPONSE TO PLANT-AVAILABLE PHOSPHORUS

Bodenhausen, N.; Somerville, V.; Desiro, A.; Walser, J.-C.; Borghi, L.; van der Heijden, M.; Schlaeppi, K.

10.1101/400119 — plant biology — Posted on 2018-08-25

621 PIRD: Pan immune repertoire database

ZHANG, W.; Wang, L.; Liu, K.; Wei, X.; Yang, K.; Du, W.; Wang, S.; Guo, N.; Ma, C.; Luo, L.; Wu, J.; Lin, L.; Yang, F.; Gao, F.; Wang, X.; Li, T.; Zhang, R.; Saksena, N. K.; Yang, H.; Wang, J.; Fang, L.; Hou, Y.; Xu, X.; Liu, X.

10.1101/399493 — immunology — Posted on 2018-08-25

622 Functional and Comparative Genomics of Niche-Specific Adapted Actinomycetes Kocuria rhizophila Strain D2 Isolated from Healthy Human Gut

Ghattargi, V. C.; Nimonkar, Y. S.; Sape, K.; Prakash, O.; Suryavanshi, M. V.; Shouche, Y. S.; Meti, B. S.; Pawar, S. P.

10.1101/400242 — genomics — Posted on 2018-08-25

623 Environments with a high probability of incompatible crosses do not select for mate avoidance in spider mites

Rodrigues, L. R.; Zele, F.; Santos, I.; Magalhaes, S.

10.1101/395301 — evolutionary biology — Posted on 2018-08-25

624 Stability of host-parasite systems: you must differ to coevolve

Berezovksaya, F. S.; Karev, G. P.; Katsnelson, M. I.; Wolf, Y. I.; Koonin, E. V.

10.1101/400150 — evolutionary biology — Posted on 2018-08-25

625 Incorporating in-source fragment information improves metabolite identification accuracy in untargeted LC-MS datasets

Seitzer, P.; Searle, B.

10.1101/399105 — bioinformatics — Posted on 2018-08-25

626 The Pemphigus Vulgaris antigen desmoglein-3 suppresses p53 function via the YAP-Hippo pathway

Wan, H.; Rehman, A.; Cai, Y.; Hünefeld, C.; Jedlickova, H.; Huang, Y.; Teh, M.-T.; Uttagomol, J.; Kang, A.; Warnes, G.; Ahmad, U.; Harwood, C. A.; Bergamaschi, D.; Parkinson, E. K.; Röcken, M.; Hart, I. R.

10.1101/399980 — cell biology — Posted on 2018-08-25

627 Toll-Like Receptor-4 Disruption Suppresses Adipose Tissue Remodeling and Increases Survival During Cancer Cachexia Syndrome

Henriques, F.; Lopes, M.; Franco, F.; Knobl, P.; Santos, K.; Bueno, L.; Correa, V.; Bedard, A.; Guilherme, A.; Birbrair, A.; Peres, S.; Farmer, S.; Batista, M. L.

10.1101/400135 — cancer biology — Posted on 2018-08-25

628 Linking Fungal and Bacterial Proliferation to Microbiologically Influenced Corrosion in B20 Biodiesel Storage Tanks

Stamps, B. W.; Bojanowski, C. L.; Drake, C. A.; Nunn, H. S.; Lloyd, P. F.; Floyd, J. G.; Berberich, K. A.; Neal, A. R.; Crookes-Goodson, W. J.; Stevenson, B. S.

10.1101/399428 — microbiology — Posted on 2018-08-25

629 Reference Set of Mycobacterium tuberculosis Clinical Strains: A tool for research and product development

Borrell, S.; Trauner, A.; Brites, D.; Rigouts, L.; Loiseau, C.; Coscolla, M.; Niemann, S.; De Jong, B.; Yeboah-Manu, D.; Kato-Maeda, M.; Feldmann, J.; Reinhard, M.; Beisel, C.; Gagneux, S.

10.1101/399709 — microbiology — Posted on 2018-08-25

630 Hemagglutinin stalk-reactive antibodies interfere with influenza virus neuraminidase activity by steric hindrance

Chen, Y.-Q.; Lan, L. Y.-L.; Huang, M.; Henry, C.; Wilson, P. C.

10.1101/400036 — microbiology — Posted on 2018-08-25

631 May the phage be with you? Prophage-like elements in the genomes of Soft Rot 3 Pectobacteriaceae (Pectobacterium spp. and Dickeya spp.)

Czajkowski, R.

10.1101/399675 — microbiology — Posted on 2018-08-25

632 A CATH domain functional family based approach to identify putative cancer driver genes and driver mutations

Ashford, P.; Pang, C. S. M.; Moya-Garcia, A. A.; Adeyelu, T.; Orengo, C.

10.1101/399014 — bioinformatics — Posted on 2018-08-25

633 Three-Dimensional Histology of Whole Zebrafish by Sub-Micron Synchrotron X-ray Micro-Tomography

Ding, Y.; Vanselow, D. J.; Yakovlev, M. A.; Katz, S. R.; Lin, A. Y.; Clark, D. P.; Vargas, P.; Xin, X.; Copper, J. E.; Canfield, V. A.; Ang, K. C.; Wang, Y.; Xiao, X.; De Carlo, F.; van Rossum, D. B.; La Riviere, P.; Cheng, K. C.

10.1101/392381 — pathology — Posted on 2018-08-25

634 Restoration of visual function by transplantation of optogenetically engineered photoreceptors

Garita-Hernandez, M.; Lampic, M.; Chaffiol, A.; Guibbal, L.; Routet, F.; Ferreira, T.; Gagliardi, G.; Reichman, S.; Picaud, S.; Sahel, J.-A.; Goureau, O.; Ader, M.; Dalkara, D.; Duebel, J.

10.1101/399725 — bioengineering — Posted on 2018-08-25

635 Regulation of tensile stress in response to external forces coordinates epithelial cell shape transitions with organ growth and elongation

Balaji, R.; Weichselberger, V.; Classen, A.-K.

10.1101/399303 — developmental biology — Posted on 2018-08-25

636 Enhanced Stability of Non-Canonical NPC2 in the symbiosome supports coral-algal symbiosis

Hambleton, E.; Jones, V. A. S.; Maegele, I.; Kvaskoff, D.; Sachsenheimer, T.; Guse, A.

10.1101/399766 — cell biology — Posted on 2018-08-25

637 Molecular noise shapes bacteria-phage ecologies

Ruess, J.; Pleska, M.; Guet, C.; Tkacik, G.

10.1101/399527 — biophysics — Posted on 2018-08-25

638 Automated sample preparation for high-throughput single-cell proteomics

Specht, H.; Harmange, G.; Perlman, D. H.; Emmott, E.; Niziolek, Z.; Budnik, B.; Slavov, N.

10.1101/399774 — systems biology — Posted on 2018-08-25

639 Structural basis of Toxoplasma gondii Perforin-Like Protein 1 membrane interaction and activity during egress

Guerra, A. J.; Zhang, O.; Bahr, C. M. E.; Huynh, M.-H.; DelProposto, J.; Brown, W. C.; Wawrzak, Z.; Koropatkin, N. M.; Carruthers, V. B.

10.1101/399204 — microbiology — Posted on 2018-08-25

640 SWI/SNF chromatin remodeling controls Notch-responsive enhancer accessibility

Pillidge, Z.; Bray, S. J.

10.1101/399501 — developmental biology — Posted on 2018-08-25

641 Basalin: an evolutionary unconstrained protein revealed via a conserved role in basal plate function

Dean, S.; Moreira-Leite, F.; Gull, K.

10.1101/398230 — cell biology — Posted on 2018-08-25

642 Molecular features of premenopausal breast cancers in Latin American women: pilot results from the PRECAMA study

Olivier, M.; Bouaoun, L.; Villar, S.; Robitaille, A.; Cahais, V.; Heguy, A.; Byrnes, G.; Le Calvez-Kelm, F.; Torres-Mejia, G.; Alvarado-Cabrero, I.; Imani-Razavi, F. S.; Ines Sanchez, G.; Jaramillo, R.; Porras, C.; Rodriguez, A. C.; Garmendia, M. L.; Soto, J. L.; Romieu, I.; Porter, P.; Guenthoer, J.; Rinaldi, S.

10.1101/396218 — cancer biology — Posted on 2018-08-25

643 RAD51 AND MITOTIC FUNCTION OF MUS81 ARE ESSENTIAL FOR RECOVERY FROM LOW-DOSE OF CAMPTOTHECIN IN THE ABSENCE OF THE WRN EXONUCLEASE

Pichierri, P.; Aiello, F. A.; Palma, A.; Malacaria, E.; Zheng, L.; Campbell, J. L.; Shen, B.; Franchitto, A.

10.1101/399881 — cell biology — Posted on 2018-08-25

644 Achieving Reversible Ligand-Protein Unbinding with Deep Learning and Molecular Dynamics through RAVE

Ribeiro, J. M. L.; Tiwary, P.

10.1101/400002 — biophysics — Posted on 2018-08-25

645 Priority effects and non-hierarchical competition shape species composition in a complex grassland community

Uricchio, L. H.; Daws, S. C.; Spear, E. R.; Mordecai, E. A.

10.1101/253518 — ecology — Posted on 2018-08-24

646 A systematic method for surveying data visualizations and a resulting genomic epidemiology visualization typology: GEViT

Crisan, A.; Gardy, J. L.; Munzner, T.

10.1101/325290 — bioinformatics — Posted on 2018-08-24

647 Longitudinal studies at birth and age 7 reveal strong effects of genetic variation on ancestry-associated DNA methylation patterns in blood cells from ethnically admixed children

McKennan, C.; Naughton, K.; Stanhope, C.; Kattan, M.; O'Connor, G.; Sandel, M.; Visness, C.; Wood, R.; Bacharier, L.; Beigelman, A.; Lovisky-Desir, S.; Togias, A.; Gern, J.; Nicolae, D.; Ober, C.

10.1101/339770 — genomics — Posted on 2018-08-24

648 A consistent picture of TRPV1 activation emerges from molecular simulations and experiments

Kasimova, M.; Yazici, A.; Yudin, Y.; Granata, D.; Klein, M. L.; Rohacs, T.; Carnevale, V.

10.1101/310151 — biophysics — Posted on 2018-08-24

649 CHASMplus reveals the scope of somatic missense mutations driving human cancers

Tokheim, C.; Karchin, R.

10.1101/313296 — bioinformatics — Posted on 2018-08-24

650 Evidence of Muller glia conversion into retina ganglion cells using Neurogenin2

Guimaraes, R. P.; Landeira, B. S.; Coelho, D. M.; Golbert, D. C.; Silveira, M. S.; Linden, R.; de Melo Reis, R. A.; Costa, M. R.

10.1101/399717 — neuroscience — Posted on 2018-08-24

651 Laminar Segregation of Sensory Coding and Behavioral Readout in Macaque V4

Moore, T.; Pettine, W. W.; Steinmetz, N. A.

10.1101/399626 — neuroscience — Posted on 2018-08-24

652 MicroRNA regulation of BMP signaling; cross-talk between endothelium and vascular smooth muscle cells

Watterston, C.; Zeng, L.; Onabadejo, A.; Childs, S. J.

10.1101/395541 — developmental biology — Posted on 2018-08-24

653 Structural insights into unique features of the human mitochondrial ribosome recycling

Koripella, R.; Sharma, M.; Risteff, P.; Keshavan, P.; Agrawal, R.

10.1101/399345 — biophysics — Posted on 2018-08-24

654 Can patients with cerebellar disease switch learning mechanisms to reduce their adaptation deficits?

Wong, A. L.; Marvel, C. L.; Taylor, J. A.; Krakauer, J. W.

10.1101/386466 — neuroscience — Posted on 2018-08-24

655 Autoimmunity to hypocretin and molecular mimicry to flu antigens in Type 1 narcolepsy

Luo, G.; Ambati, A.; Lin, L.; Bonvalet, M.; Partinen, M.; Ji, X.; Maecker, H. T.; Mignot, E.

10.1101/378109 — immunology — Posted on 2018-08-24

656 Gene-Specific Predictability of Protein Levels from mRNA Data in Humans

Moulana, A.; Scanteianu, A.; Jones, D.; Stern, A. D.; Bouhaddou, M.; Birtwistle, M.

10.1101/399816 — systems biology — Posted on 2018-08-24

657 DEBrowser: Interactive Differential Expression Analysis and Visualization Tool for Count Data

Kucukural, A.; Yukselen, O.; Ozata, D. M.; Moore, M. J.; Garber, M.

10.1101/399931 — bioinformatics — Posted on 2018-08-24

658 Modeling motor neuron resilience in ALS using stem cells

Allodi, I.; Nijssen, J.; Aguila Benitez, J. C.; Bonvicini, G.; Cao, M.; Hedlund, E.

10.1101/399659 — neuroscience — Posted on 2018-08-24

659 Cold trapped - Correcting locomotion dependent observation biases in thermal preference of Drosophila

Giraldo, D.; Adden, A. K.; Kuhlemann, I.; Gras, H.; Geurten, B. R. H.

10.1101/400069 — neuroscience — Posted on 2018-08-24

660 Trans-splicing of the C. elegans let-7 primary transcript developmentally regulates let-7 microRNA biogenesis and let-7 family microRNA activity

Nelson, C.; Ambros, V.

10.1101/400077 — molecular biology — Posted on 2018-08-24

661 Designing a Study of Correlates of Risk for Ebola Vaccination

Halloran, M. E.; Longini, I. M.; Gilbert, P. B.

10.1101/397547 — epidemiology — Posted on 2018-08-24

662 Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell counts and epigenetic ageing

Stevenson, A. J.; McCartney, D. L.; Harris, S. E.; Taylor, A. M.; Redmond, P.; Starr, J. M.; Zhang, Q.; McRae, A. F.; Wray, N. R.; Spires-Jones, T. L.; McColl, B. W.; McIntosh, A. M.; Deary, I. J.; Marioni, R. E.

10.1101/397877 — epidemiology — Posted on 2018-08-24

663 Multiple Exposures, Reinfection, and Risk of Progression to Active Tuberculosis

Ackley, S.; Lee, R. S.; Worden, L.; Zwick, E.; Porco, T. C.; Behr, M. A.; Pepperell, C. S.

10.1101/398271 — epidemiology — Posted on 2018-08-24

664 The association between adiposity and inpatient hospital costs in the UK Biobank cohort

Dixon, P.; Davey Smith, G.; Hollingworth, W.

10.1101/399600 — epidemiology — Posted on 2018-08-24

665 Clustering Analysis To Explore Cohorts In Comorbid Patients

Karkare, R.

10.1101/396481 — epidemiology — Posted on 2018-08-24

666 Direct estimation of HDL-mediated cholesterol efflux capacity from serum

Kuusisto, S.; Holmes, M. V.; Ohukainen, P.; Kangas, A. J.; Karsikas, M.; Tiainen, M.; Perola, M.; Salomaa, V.; Kettunen, J.; Ala-Korpela, M.

10.1101/396929 — epidemiology — Posted on 2018-08-24

667 Occurrence of non-western magic in the European brain

Koten, J. W.; Schueppen, A.; Kumar, V.; Wood, G.

10.1101/395285 — neuroscience — Posted on 2018-08-24

668 Forecasting seasonal influenza in the U.S.: A collaborative multi-year, multi-model assessment of forecast performance

Reich, N. G.; Brooks, L.; Fox, S.; Kandula, S.; McGowan, C.; Moore, E.; Osthus, D.; Ray, E. L.; Tushar, A.; Yamana, T.; Biggerstaff, M.; Johansson, M. A.; Rosenfeld, R.; Shaman, J.

10.1101/397190 — epidemiology — Posted on 2018-08-24

669 Prestimulus Activity in the Cingulo-Opercular Network Predicts Memory for Naturalistic Episodic Experience

Cohen, N.; Ben-Yakov, A.; Weber, J.; Edelson, M.; Paz, R.; Dudai, Y.

10.1101/176057 — neuroscience — Posted on 2018-08-24

670 Latent Structure of Risk Perception

Pabon, E.; MacKillop, J.; Palmer, A.; de Wit, H.

10.1101/389890 — neuroscience — Posted on 2018-08-24

671 A comprehensive genomics solution for HIV surveillance and clinical monitoring in a global health setting

10.1101/397083 — genomics — Posted on 2018-08-24

672 Voltage-gated Proton Channel Hv1 Supports Insulin Secretion in Pancreatic β Cells through calcium entry, depolarization and intracellular pH regulation

Pang, H.; Wang, X.; Xi, W.; Zhao, Q.; Zhang, S.; Qin, J.; Lv, J.; Che, Y.; Zuo, W.; Li, S. J.

10.1101/097816 — cell biology — Posted on 2018-08-24

673 Systems Biology Understanding of the Effects of Lithium on Cancer.

Ge, W.; Jakobsson, E.

10.1101/363077 — cancer biology — Posted on 2018-08-24

674 Adaptive evolution of feed-forward loops versus diamonds to filter out short spurious signals

Xiong, K.; Lancaster, A. K.; Siegal, M. L.; Masel, J.

10.1101/393884 — systems biology — Posted on 2018-08-24

675 Physical activity predicts population-level age-related differences in frontal white matter

Strommer, J. M.; Davis, S. W.; Henson, R. N.; Tyler, L. K.; Cam-CAN, ; Campbell, K. L.

10.1101/311050 — neuroscience — Posted on 2018-08-24

676 Nascent chromatin occupancy profiling reveals locus and factor specific chromatin maturation dynamics behind the DNA replication fork

Gutierrez, M. P.; MacAlpine, H. K.; MacAlpine, D.

10.1101/398438 — genomics — Posted on 2018-08-24

677 Context dependent roles for RB-E2F transcriptional regulation in tumor suppression

Dick, F.; Thwaites, M.; Cecchini, M.; Passos, D.

10.1101/399956 — cancer biology — Posted on 2018-08-24

678 A Multimodal Adaptive Super-Resolution and Confocal Microscope

Valiya Peedikakkal, L.; Furley, A.; Cadby, A. J.

10.1101/397273 — biophysics — Posted on 2018-08-24

679 miR-210 controls the evening phase of circadian locomotor rhythms through repression of Fasciclin 2

Leigh, W.; Liu, Z.; Nian, X.; Zhang, Y.

10.1101/399873 — neuroscience — Posted on 2018-08-24

680 HDAC Inhibitors Rescue Multiple Disease-Causing CFTR Variants

Angles, F.; Hutt, D.; Balch, W. E.; McGuckian, M.

10.1101/399451 — cell biology — Posted on 2018-08-24

681 Perceptual inference employs intrinsic alpha frequency to resolve perceptual ambiguity

Shen, L.; Han, B.; Chen, L.; Chen, Q.

10.1101/399840 — neuroscience — Posted on 2018-08-24

682 Therapeutic effects of favipiravir against severe fever with thrombocytopenia syndrome virus infection in a lethal mouse model: dose-efficacy studies upon oral administration

TANI, H.; Komeno, T.; Fukuma, A.; Fukushi, S.; Taniguchi, S.; Shimojima, M.; Uda, A.; Morikawa, S.; Nakajima, N.; Furuta, Y.; Saijo, M.

10.1101/399899 — microbiology — Posted on 2018-08-24

683 Pharmacovigilance or patient safety: analysis from a patient safety program

Cortazar, Y. C.; Orozco, J. G.; Lopez, J. J.

10.1101/399923 — epidemiology — Posted on 2018-08-24

684 Improvement of arthroscopic surgical performance using a new wide-angle arthroscope

Kwak, J.-M.; Kholinne, E.; Sun, Y.; Koh, K.-H.; Jeon, I.-H.

10.1101/399907 — scientific communication and education — Posted on 2018-08-24

685 Acute muscle fatigue and CPR quality assisted by visual feedback devices: a randomized-crossover simulation trial

Abelairas-Gomez, C.; Rey, E.; Gonzalez-Salvado, V.; Mecias-Calvo, M.; Rodriguez-Ruiz, E.; Rodriguez-Nunez, A.

10.1101/399949 — physiology — Posted on 2018-08-24

686 Chronotopic Maps in Human Medial Premotor Cortex

Protopapa, F.; Hayashi, M.; Kulashekhar, S.; van der Zwaag, W.; Battistella, G.; Murray, M. M.; Kanai, R.; Bueti, D.

10.1101/399857 — neuroscience — Posted on 2018-08-24

687 Large scale changes in host methylation patterns induced by IncA/C plasmid transformation in Vibrio cholerae

Wang, R.; Wan, K.

10.1101/399964 — microbiology — Posted on 2018-08-24

688 EGFR SIGNALING COORDINATES PATTERNING WITH CELL SURVIVAL DURING DROSOPHILA EPIDERMAL DEVELOPMENT

Crossman, S. H.; Streichan, S.; vincent, J.-P.

10.1101/399865 — developmental biology — Posted on 2018-08-24

689 Dynamic Regulation of RNA Structure in Mammalian Cells

Sun, l.; Fazal, F.; Li, P.; Broughton, J.; Lee, B.; Tang, L.; Huang, W.; Chang, H.; Zhang, Q. C.

10.1101/399386 — molecular biology — Posted on 2018-08-24

690 MetaPGN: a pipeline for construction and graphical visualization of annotated pangenome networks

Peng, Y.; Tang, S.; WANG, D.; Zhong, H.; Jia, H.; Cai, X.; Zhang, Z.; Xiao, M.; Yang, H.; Wang, J.; Kristiansen, K.; Xu, X.; li, j.

10.1101/398636 — genomics — Posted on 2018-08-24

691 Gene flow improves fitness at a range edge under climate change

Bontrager, M.; Angert, A.

10.1101/399469 — evolutionary biology — Posted on 2018-08-24

692 Genomic signatures of sympatric speciation with historical and contemporary gene flow in a tropical anthozoan

Titus, B. M.; Blischak, P. D.; Daly, M.

10.1101/399360 — evolutionary biology — Posted on 2018-08-24

693 Cardiovascular responses to antigravity muscle loading during head-down tilt at rest and after dynamic exercises

Alessandro, C.; Sarabadani Tafreshi, A.; Riener, R.

10.1101/399477 — physiology — Posted on 2018-08-24

694 “Global Transcriptional Response to CRISPR/CAS9-AAV6 Based Genome Editing” Matches Transcriptional Response to Specific Small Molecule Perturbations

Nordor, A. V.; Aryee, M. J.; Siwo, G. H.

10.1101/399311 — molecular biology — Posted on 2018-08-24

695 Characterization of emetic and diarrheal Bacillus cereus strains from a 2016 foodborne outbreak using whole-genome sequencing: addressing the microbiological, epidemiological, and bioinformatic challenges

Carroll, L. M.; Wiedmann, M.; Mukherjee, M.; Nicholas, D. C.; Mingle, L. A.; Dumas, N. B.; Cole, J. A.; Kovac, J.

10.1101/399287 — microbiology — Posted on 2018-08-24

696 Eukaryotic acquisition of a bacterial operon

Kominek, J.; Doering, D. T.; Opulente, D. A.; Shen, X.-X.; Zhou, X.; DeVirgilio, J.; Hulfachor, A. B.; Kurtzman, C. P.; Rokas, A.; Hittinger, C. T.

10.1101/399394 — evolutionary biology — Posted on 2018-08-24

697 Integrated modeling of peptide digestion and detection for the prediction of proteotypic peptides in targeted proteomics

Gao, Z.; Chang, C.; Zhu, Y.; Fu, Y.

10.1101/399436 — bioinformatics — Posted on 2018-08-24

698 DeepCAPE: a deep convolutional neural network for the accurate prediction of enhancers

Chen, S.; Gan, M.; Lv, H.; Jiang, R.

10.1101/398115 — bioinformatics — Posted on 2018-08-24

699 Pairwise Efficiency: A new mathematical approach to qPCR data analysis increases the precision of the classical calibration curve assay

Panina, Y.; Germond, A.; David, G. B.; Watanabe, T. M.

10.1101/399337 — biochemistry — Posted on 2018-08-24

700 Relative value perception in an insect: positive and negative incentive contrasts in ants

Wendt, S.; Strunk, K. S.; Heinze, J.; Roider, A.; Czaczkes, T. J.

10.1101/330241 — animal behavior and cognition — Posted on 2018-08-24

701 Local Homogeneity of Tonotopic Organization in the Primary Auditory Cortex of Marmosets

Zeng, H.-h.; Huang, J.-f.; Chen, M.; Wen, Y.-q.; Shen, Z.-m.; Poo, M.-m.

10.1101/398677 — neuroscience — Posted on 2018-08-24

702 Lysosome exocytosis is required for mitosis

Nugues, C.; Helassa, N.; Burgoyne, R.; Haynes, L.

10.1101/375816 — cell biology — Posted on 2018-08-24

703 PHASE TRANSITIONED NUCLEAR OSKAR PROMOTES CELL DIVISION OF DROSOPHILA PRIMORDIAL GERM CELLS

Kistler, K. E.; Trcek, T.; Hurd, T. R.; Chen, R.; Liang, F.-X.; Sall, J.; Kato, M.; Lehmann, R.

10.1101/397992 — cell biology — Posted on 2018-08-24

704 Parallel encoding of information into visual short-term memory

Dalmaijer, E. S.; Manohar, S. G.; Husain, M.

10.1101/398990 — neuroscience — Posted on 2018-08-24

705 Hysteresis in the thermal relaxation dynamics of an immune complex as basis for molecular memory

Stan, R. C.; Camargo, M. M. d.

10.1101/398966 — biophysics — Posted on 2018-08-24

706 Mechanical vibration does not systematically reduce the tremor in Essential Tremor patients

Lora-Millan, J. S.; Lopez-Blanco, R.; Gallego, J. A.; Benito-Leon, J.; Gonzalez de la Aleja, J.; Rocon, E.

10.1101/398875 — bioengineering — Posted on 2018-08-24

707 How genetic disease risks can be misestimated across global populations

Kim, M. S.; Patel, K. P.; Teng, A. K.; Berens, A. J.; Lachance, J.

10.1101/195768 — genomics — Posted on 2018-08-23

708 Structural insights into unique features of the human mitochondrial ribosome recycling

Koripella, R.; Sharma, M.; Risteff, P.; Keshavan, P.; Agrawal, R.

10.1101/399345 — biophysics — Posted on 2018-08-23

709 Loss of Trans Regulation in Breast Cancer Molecular Subtypes

Garcia-Cortes, D.; de Anda-Jauregui, G.; Fresno, C.; Hernandez-Lemus, E.; Espinal-Enriquez, J.

10.1101/399253 — systems biology — Posted on 2018-08-23

710 An open-source control system for in vivo fluorescence measurements from deep-brain structures

Owen, S. F.; Kreitzer, A. C.

10.1101/399329 — neuroscience — Posted on 2018-08-23

711 Epigenetic factors coordinate intestinal development

Ganz, J.; Melancon, E.; Wilson, C.; Amores, A.; Batzel, P.; Strader, M.; Braasch, I.; Diba, P.; Kuhlman, J. A.; Postlethwait, J. H.; Eisen, J. S.

10.1101/399410 — developmental biology — Posted on 2018-08-23

712 Orientation processing by synaptic integration across first-order tactile neurons

Hay, E.; Pruszynski, J. A.

10.1101/396705 — neuroscience — Posted on 2018-08-23

713 A 3D model of human skeletal muscle innervated with stem cell-derived motor neurons enables epsilon-subunit targeted myasthenic syndrome studies

Afshar Bakooshli, M.; Lippmann, E. S.; Mulcahy, B.; Iyer, N.; Nguyen, C. T.; Tung, K.; Stewart, B. A.; Mouly, V.; Pegoraro, E.; Ahn, H.; Ginsberg, H.; Zhen, M.; Ashton, R. S.; Gilbert, P. M.

10.1101/275545 — bioengineering — Posted on 2018-08-23

714 Resource limitation modulates the fate of dissimilated nitrogen in a dual-pathway Actinobacterium

Vuono, D. C.; Read, R. W.; Hemp, J.; Sullivan, B. W.; Arnone, J. A.; Neveux, I.; Blank, B.; Staub, C.; Loney, E.; Miceli, D.; Winkler, M.; Chakraborty, R.; Stahl, D. A.; Grzymski, J. J.

10.1101/364331 — microbiology — Posted on 2018-08-23

715 Putative pore-forming subunits of the mechano-electrical transduction channel, Tmc1/2b, require Tmie to localize to the site of mechanotransduction in zebrafish sensory hair cells

Pacentine, I.; Nicolson, T.

10.1101/393330 — neuroscience — Posted on 2018-08-23

716 Fast open modification spectral library searching through approximate nearest neighbor indexing

Bittremieux, W.; Meysman, P.; Noble, W. S.; Laukens, K.

10.1101/326173 — bioinformatics — Posted on 2018-08-23

717 Positive and negative plant-soil feedbacks are caused by mycorrhizal type, soil fertility, and phylogenetic relatedness in a mixed Dipterocarp rain forest

Segnitz, R. M.; Russo, S. E.; Davies, S. J.; Peay, K.

10.1101/399295 — ecology — Posted on 2018-08-23

718 Hippocampal neurogenesis promotes preference for future rewards

Seib, D. R.; Espinueva, D.; Princz-Lebel, O.; Chahley, E.; Floresco, S. B.; Snyder, J. S.

10.1101/399261 — neuroscience — Posted on 2018-08-23

719 Characterization of Coxsackievirus A20 from a child with acute flaccid paralysis in Nigeria

Faleye, T. O. C.; Adewumi, M. O.; Olayinka, O. T.; Adeniji, J. A.

10.1101/399212 — genomics — Posted on 2018-08-23

720 Differences in DNA methylation of white blood cell types at birth and in adulthood reflect postnatal immune maturation and influence accuracy of cell type prediction

Jones, M.; Dinh, L.; Razzaghian, H. R.; de Goede, O.; MacIsaac, J. L.; Morin, A. M.; Gervin, K.; Ng, R.; Duijts, L.; van Zelm, M. C.; Moll, H. A.; Lyle, R.; Robinson, W. P.; Koestler, D. C.; Felix, J. F.; Lavoie, P. M.; Mostafavi, S.; Kobor, M. S.

10.1101/399279 — genetics — Posted on 2018-08-23

721 Continual exit of human cutaneous resident memory CD4 T cells that seed distant skin sites

Klicznik, M. M.; Morawski, P. A.; Höllbacher, B.; Varkhande, S.; Motley, S.; Rosenblum, M. D.; Long, S. A.; Brachtl, G.; Duhen, T.; Campbell, D.; Gratz, I. K.

10.1101/361758 — immunology — Posted on 2018-08-23

722 On The Peopling Of The Americas: Molecular Evidence For The Paleoamerican And The Solutrean Models

Yuan, D.; Huang, S.

10.1101/130989 — evolutionary biology — Posted on 2018-08-23

723 Asymmetric histone incorporation during DNA replication in Drosophila male germline stem cells

Wooten, M.; Snedeker, J.; Nizami, Z.; Yang, X.; Urban, E.; Feng, X. A.; Kim, J. M.; Gall, J.; Xiao, J.; Chen, X.

10.1101/242768 — developmental biology — Posted on 2018-08-23

724 Sparse-Coding Variational Auto-Encoders

Barello, G.; Charles, A.; Pillow, J.

10.1101/399246 — neuroscience — Posted on 2018-08-23

725 Bariatric surgery changes gut microbiota composition independent of operation type

Paganelli, F. L.; Luyer, M.; Hazelbag, C. M.; Uh, H.-W.; Rogers, M. R. C.; Adriaans, D.; Berbers, R.-M.; Hendrickx, A. P. A.; Viveen, M. C.; Groot, J. A.; Bonten, M. J. M.; Fluit, A. C.; Willems, R. J. L.; Leavis, H.

10.1101/395657 — microbiology — Posted on 2018-08-23

726 Nascent chromatin occupancy profiling reveals locus and factor specific chromatin maturation dynamics behind the DNA replication fork

Gutierrez, M. P.; MacAlpine, H. K.; MacAlpine, D.

10.1101/398438 — genomics — Posted on 2018-08-23

727 Parvalbumin loss following chronic sub-anesthetic NMDA antagonist treatment is age-dependent in the hippocampus: Implications for modeling NMDA hypofunction

Honeycutt, J. A.; Chrobak, J. J.

10.1101/399188 — neuroscience — Posted on 2018-08-23

728 Epigenomic landscape of the human pathogen Clostridium difficile

Oliveira, P. H.; Kim, A.; Sekulovic, O.; Garrett, E. M.; Trzilova, D.; Mead, E. A.; Pak, T.; Zhu, S.; Deikus, G.; Touchon, M.; Beckford, C.; Zeitouni, N. E.; Altman, D.; Webster, E.; Oussenko, I.; Aggarwal, A. K.; Bashir, A.; Patel, G.; Hamula, C.; Huprikar, S.; Roberts, R. J.; Schadt, E. E.; Sebra, R.; Bakel, H. v.; Kasarskis, A.; Tamayo, R.; Shen, A.; Fang, G.

10.1101/398891 — genomics — Posted on 2018-08-23

729 Investigation of the Relationship between Markers of Systemic Inflammatory Response and Head and Neck Tumor Characteristics

Tham, T.; Khaymovich, J.; Costantino, P.

10.1101/399162 — cancer biology — Posted on 2018-08-23

730 EndoC-βH1 multi-genomic profiling defines gene regulatory programs governing human pancreatic β cell identity and function

Lawlor, N.; Marquez, E. J.; Orchard, P.; Narisu, N.; Shamim, M. S.; Thibodeau, A.; Varshney, A.; Kursawe, R.; Erdos, M. R.; Kanke, M.; Gu, H.; Pak, E.; Dutra, A.; Russell, S.; Li, X.; Piecuch, E.; Luo, O.; Chines, P. S.; Fuchbserger, C.; Sethupathy, P.; Aiden, A. P.; Ruan, Y.; Aiden, E. L.; Collins, F. S.; Ucar, D.; Parker, S. C. J.; Stitzel, M. L.

10.1101/399139 — genomics — Posted on 2018-08-23

731 Kinpute: Using identity by descent to improve genotype imputation

Abney, M.; El Sherbiny, A.

10.1101/399147 — genetics — Posted on 2018-08-23

732 Beyond stability constraints: a biophysical model of enzyme evolution with selection for stability and activity

Echave, J.

10.1101/399154 — biophysics — Posted on 2018-08-23

733 Intact mast cell content during mild head injury is required for the development of latent pain sensitization - implications for mechanisms underlying posttraumatic headache

Bree, D.; Levy, D.

10.1101/392928 — neuroscience — Posted on 2018-08-23

734 Draft Aphaenogaster genomes expand our view of ant genome size variation across climate gradients

Lau, M.; Ellison, A. M.; Nguyen, A. D.; Penick, C.; DeMarco, B.; Gotelli, N. J.; Sanders, N.; Dunn, R.; Helms Cahan, S.

10.1101/302679 — genomics — Posted on 2018-08-23

735 A comprehensive genomics solution for HIV surveillance and clinical monitoring in a global health setting

10.1101/397083 — genomics — Posted on 2018-08-23

736 Anticancer Drug Impact on DNA - A Study by Neutron Spectrocopy, Synchrotron-based FTIR and EXAFS

Batista de Carvalho, A. L. M.; Mamede, A. P.; Dopplapudi, A.; Garcia Sakai, V.; Doherty, J.; Frogley, M.; Cinque, G.; Gardner, P.; Gianolio, D.; Batista de Carvalho, L. A. E.; Marques, M. P. M.

10.1101/398826 — biophysics — Posted on 2018-08-23

737 DART-ID increases single-cell proteome coverage

Chen, A.; Franks, A.; Slavov, N.

10.1101/399121 — genomics — Posted on 2018-08-23

738 Intragenomic Conflict over Bet-Hedging

Wilkins, J. F.; Bhattacharya, T.

10.1101/364190 — evolutionary biology — Posted on 2018-08-23

739 Torpor duration, more than temperature, is key to hummingbird nighttime energy savings

Shankar, A.; Schroeder, R. J.; Wethington, S. M.; Graham, C. H.; Powers, D. R.

10.1101/383679 — ecology — Posted on 2018-08-23

740 Transcriptomic and functional analysis of the oosome, a unique form of germ plasm in the wasp Nasonia vitripennis

Quan, H.; Lynch, J. A.

10.1101/384032 — developmental biology — Posted on 2018-08-23

741 Exploring the genetic correlations of antisocial behavior and life history traits

Tielbeek, J.; Barnes, J. C.; Popma, A.; Polderman, T.; Lee, J. J.; Perry, J. B.; Posthuma, D.; Boutwell, B. B.

10.1101/247411 — genomics — Posted on 2018-08-23

742 Parallel adaptations to different host plants despite clonal reproduction in the world most devastating nematode pest

Koutsovoulos, G.; Marques, E.; Arguel, M.-J.; Machado, A. C.; Carneiro, R. M.; Castagnone-Sereno, P.; Danchin, E. G.; Albuquerque, E. V.

10.1101/362129 — evolutionary biology — Posted on 2018-08-23

743 Data quality reporting: good practice for transparentestimates from forest and land cover surveys

Birigazzi, L.; Gregoire, T. G.; Finegold, Y.; Condor Goled, R. D.; Sandker, M.; Donegan, E.; Gamarra, J. G. P.

10.1101/399055 — ecology — Posted on 2018-08-23

744 Integrative pathway enrichment analysis of multivariate omics data

Paczkowska, M.; Barenboim, J.; Sintupisut, N.; Fox, N. C.; Zhu, H.; Abd-Rabbo, D.; PCAWG Network and Pathway Analysis Group, ; Boutros, P. C.; Reimand, J.

10.1101/399113 — bioinformatics — Posted on 2018-08-23

745 EEG-based auditory attention detection: boundary conditions for background noise and speaker positions

Das, N.; Bertrand, A.; Francart, T.

10.1101/312827 — bioengineering — Posted on 2018-08-23

746 Rapid Time Resolved Analysis of Filament Motility

Ijpma, G.; Balassy, Z.; Lauzon, A.-M.

10.1101/399006 — molecular biology — Posted on 2018-08-23

747 Hysteresis in the thermal relaxation dynamics of an immune complex as basis for molecular memory

Stan, R. C.; Camargo, M. M. d.

10.1101/398966 — biophysics — Posted on 2018-08-23

748 Parallel encoding of information into visual short-term memory

Dalmaijer, E. S.; Manohar, S. G.; Husain, M.

10.1101/398990 — neuroscience — Posted on 2018-08-23

749 Genome-wide Estrogen Receptor-alpha activation is sustained, not cyclical

Holding, A. N.; Cullen, A. E.; Markowetz, F.

10.1101/398925 — cancer biology — Posted on 2018-08-23

750 PAVOOC: Designing CRISPR sgRNAs using 3D protein structures and functional domain annotation

Schaefer, M.; Clevert, D.-A.; Weiss, B.; Steffen, A.

10.1101/398859 — bioinformatics — Posted on 2018-08-23

751 Updating genome annotation for the microbial cell factory Aspergillus niger using gene co-expression networks

Schaepe, P.; Kwon, M. J.; Baumann, B.; Gutschmann, B.; Jung, S.; Lenz, S.; Nitsche, B.; Paege, N.; Schuetze, T.; Cairns, T.; Meyer, V.

10.1101/398842 — systems biology — Posted on 2018-08-23

752 Neuronal Adaptation to the Value Range in Macaque Orbitofrontal Cortex

Conen, K.; Padoa-Schioppa, C.

10.1101/399071 — neuroscience — Posted on 2018-08-23

753 Assessment of the zoonotic potential of the ruminant-associated influenza D virus

Holwerda, M.; Portmann, J.; Stalder, H.; Dijkman, R.

10.1101/395517 — microbiology — Posted on 2018-08-23

754 Long-read Sequencing Uncovers a Complex Transcriptome Topology in Varicella Zoster Virus

Prazsak, I.; Moldovan, N.; Tombacz, D.; Megyeri, K.; Szucs, A.; Csabai, Z.; Boldogkoi, Z.

10.1101/399048 — genomics — Posted on 2018-08-23

755 On the feasibility of saltational evolution

Katsnelson, M. I.; Wolf, Y. I.; Koonin, E. V.

10.1101/399022 — evolutionary biology — Posted on 2018-08-23

756 effectR: An expandable R package to predict candidate effectors

Tabima, J. F.; Grunwald, N. J.

10.1101/398404 — bioinformatics — Posted on 2018-08-23

757 Pericentromeric hypomethylation elicits an interferon response in an animal model of ICF syndrome

Rajshekar, S.; Yao, J.; Arnold, P. K.; Payne, S. G.; Zhang, Y.; Bowman, T. V.; Schmitz, R. J.; Edwards, J. R.; Goll, M. G.

10.1101/396671 — molecular biology — Posted on 2018-08-23

758 SHORT TERM EVOLUTIONARY DYNAMICS OF ESCHERICHIA COLI IN DIFFERENT CARBON ENVIRONMENTS

Choudhury, D.; Saini, S.

10.1101/398578 — microbiology — Posted on 2018-08-23

759 Isolated individuals and groups show opposite preferences toward humidity

Calvo Martin, M.; Nicolis, S. C.; Planas-Sitja, I.; de Biseau, J.-C.; Deneubourg, J.-L.

10.1101/398651 — animal behavior and cognition — Posted on 2018-08-23

760 Calicivirus VP2 forms a portal to mediate endosome escape

Conley, M. J.; McElwee, M.; Azmi, L. B.; Gabrielsen, M.; Byron, O.; Goodfellow, I. G.; Bhella, D.

10.1101/397901 — microbiology — Posted on 2018-08-23

761 Telescope: Characterization of the retrotranscriptome by accurate estimation of transposable element expression

Bendall, M. L.; de Mulder, M.; Iniguez, L. P.; Lecanda-Sanchez, A.; Perez-Losada, M.; Ostrowski, M. A.; Jones, R. B.; Mulder, L.; Reyes-Teran, G.; Crandall, K. A.; Ormsby, C. E.; Nixon, D. F.

10.1101/398172 — genomics — Posted on 2018-08-23

762 Nascent chromatin occupancy profiling reveals locus and factor specific chromatin maturation dynamics behind the DNA replication fork

Gutierrez, M. P.; MacAlpine, H. K.; MacAlpine, D.

10.1101/398438 — genomics — Posted on 2018-08-23

763 Development of an eDNA method for monitoring fish communities: ground truthing in diverse lakes with characterised fish faunas

Li, J.; Hatton-Ellis, T. W.; Lawson Handley, L.-J.; Kimbell, H. S.; Benucci, M.; Peirson, G.; Haenfling, B.

10.1101/394718 — ecology — Posted on 2018-08-23

764 Mechanical vibration does not systematically reduce the tremor in Essential Tremor patients

Lora-Millan, J. S.; Lopez-Blanco, R.; Gallego, J. A.; Benito-Leon, J.; Gonzalez de la Aleja, J.; Rocon, E.

10.1101/398875 — bioengineering — Posted on 2018-08-23

765 Group Based Trajectory Analysis of Cognitive Outcomes in Children with Perinatal HIV

Patel, P.; Apornpong, T.; Kerr, S. J.; Puthanakit, T.; Thongpibul, K.; Kosalaraksa, P.; Ounchanum, P.; Kanhanavanit, S.; Ngampiyaskul, C.; Penhsun, L.; Chettra, K.; Spudich, S.; Ananworanich, J.; Luesonboon, W.; Mellins, C.; Malee, K.; Paul, R.; The PREDICT Resilience Study,

10.1101/398339 — neuroscience — Posted on 2018-08-23

766 Thalamo-cortical interactions define functional dissociations across the macaque attention network

Fiebelkorn, I. C.; Pinsk, M. A.; Kastner, S.

10.1101/398917 — neuroscience — Posted on 2018-08-23

767 Swarming bacteria respond to increasing barriers to motility by increasing cell length and modifying colony structure

Little, K.; Austerman, J. L.; Zheng, J.; Gibbs, K. A.

10.1101/398321 — microbiology — Posted on 2018-08-23

768 Meta-organization of Translation Centers Revealed by Proximity Mapping of Endoplasmic Reticulum Ribosome Interactors

Hoffman, A. M.; Nicchitta, C. V.

10.1101/398669 — cell biology — Posted on 2018-08-23

769 Activation of TAp73 and inhibition of thioredoxin reductase for improved cancer therapy in TP53 mutant pancreatic tumors

Acedo, P.; Fernandes, A.; Zawacka-Pankau, J.

10.1101/398750 — cancer biology — Posted on 2018-08-23

770 A pipeline for rapidly generating genetically engineered mouse models of pancreatic cancer using in vivo CRISPR-Cas9 mediated somatic recombination

Ideno, N.; Yamaguchi, H.; Okumara, T.; Huang, J.; Brun, M. J.; Ho, M. L.; Suh, J.; Gupta, S.; Maitra, A.; Ghosh, B.

10.1101/398347 — cancer biology — Posted on 2018-08-23

771 Different neural networks for conceptual retrieval in sighted and blind reveal the experiential bases of knowledge.

Bottini, R.; Ferraro, S.; Nigri, A.; Cuccarini, V.; Bruzzone, M. G.; Collignon, O.

10.1101/384552 — neuroscience — Posted on 2018-08-23

772 Local Homogeneity of Tonotopic Organization in the Primary Auditory Cortex of Marmosets

Zeng, H.-h.; Huang, J.-f.; Chen, M.; Wen, Y.-q.; Shen, Z.-m.; Poo, M.-m.

10.1101/398677 — neuroscience — Posted on 2018-08-23

773 Nucleosome dynamics of human iPSC during the early stages of neurodevelopment

Harwood, J. C.; Kent, N. A.; Allen, N. D.; Harwood, A. J.

10.1101/398792 — genomics — Posted on 2018-08-23

774 Gene expression plasticity and frontloading promote thermotolerance in Pocilloporid corals

Brener-Raffalli, K.; Vidal-Dupiol, J.; Adjeroud, M.; Rey, O.; Romans, P.; Bonhomme, F.; Pratlong, M.; Haguenauer, A.; Pillot, R.; Feuillassier, L.; Claereboudt, M.; Magalon, H.; Gelin, P.; Pontarotti, P.; Aurelle, D.; Mitta, G.; Toulza, E.

10.1101/398602 — evolutionary biology — Posted on 2018-08-23

775 The transmembrane protein Crb2a regulates cardiomyocyte apicobasal polarity and adhesion in zebrafish

Vanesa, J.-A.; Stainier, D. Y. R.

10.1101/398909 — developmental biology — Posted on 2018-08-23

776 CA3 place cells that represent a novel waking experience are preferentially reactivated during sharp wave-ripples in subsequent sleep

Hwaun, E.; Colgin, L. L.

10.1101/398560 — neuroscience — Posted on 2018-08-23

777 Small molecule inhibition of IRE1α kinase/RNase has anti-fibrotic effects in the lung

Thamsen, M.; Ghosh, R.; Auyeung, V. C.; Brumwell, A.; Chapman, H. A.; Backes, B. J.; Perara, G.; Maly, D. J.; Sheppard, D.; Papa, F. R.

10.1101/398552 — molecular biology — Posted on 2018-08-23

778 Viral Infection Skews Immunoglobulin Light Chain Repertoire Diversity

Schwartz, J. C. C.; Murtaugh, M. P.

10.1101/398529 — immunology — Posted on 2018-08-23

779 Tissue- and sex-specific small RNAomes reveal sex differences in response to the environment

Bezler, A.; Braukmann, F.; West, S.; Duplan, A.; Conconi, R.; Schuetz, F.; Goenczy, P.; Piano, F.; Gunsalus, K.; Miska, E.; Keller, L.

10.1101/398784 — genomics — Posted on 2018-08-23

780 Predicting protein-peptide interaction sites using distant protein complexes as structural templates

Johansson-Akhe, I.; Mirabello, C.; Wallner, B.

10.1101/398768 — bioinformatics — Posted on 2018-08-23

781 When higher carrying capacities lead to faster propagation

Haond, M.; Morel-Journel, T.; Lombaert, E.; Vercken, E.; Mailleret, L.; Roques, L.

10.1101/307322 — ecology — Posted on 2018-08-23

782 iCARE: An R Package to Build, Validate and Apply Absolute Risk Models

Pal Choudhury, P.; Maas, P.; Wilcox, A.; Wheeler, W.; Brook, M.; Check, D.; Garcia-Closas, M.; Chatterjee, N.

10.1101/079954 — bioinformatics — Posted on 2018-08-23

783 Toward a 3D model of phyllotaxis based on a biochemically plausible auxin-transport mechanism

Hartmann, F. P.; Barbier de Reuille, P.; Kuhlemeier, C.

10.1101/398628 — plant biology — Posted on 2018-08-23

784 Noise propagation in an integrated model of bacterial gene expression and growth

Kleijn, I. T.; Krah, L. H. J.; Hermsen, R.

10.1101/246165 — systems biology — Posted on 2018-08-23

785 Positive human health effects of sea spray aerosols: molecular evidence from exposed lung cell lines.

Asselman, J.; Van Acker, E.; De Rijcke, M.; Tilleman, L.; Van Nieuwerburgh, F.; Mees, J.; De Schamphelaere, K.; Janssen, C.

10.1101/397141 — pharmacology and toxicology — Posted on 2018-08-23

786 Phylogeographic analysis and identification of factors impacting the diffusion of Foot-and-Mouth disease virus in Africa

Duchatel, F.; Bronsvoort, M.; Lycett, S.

10.1101/358044 — evolutionary biology — Posted on 2018-08-23

787 Uneven missing data skews phylogenomic relationships within the lories and lorikeets

Smith, B. T.; Mauck, W. M.; Benz, B.; Andersen, M. J.

10.1101/398297 — evolutionary biology — Posted on 2018-08-23

788 RAVEN 2.0: a versatile toolbox for metabolic network reconstruction and a case study on Streptomyces coelicolor

Wang, H.; Marcisauskas, S.; Sanchez, B. J.; Domenzain, I.; Hermansson, D.; Agren, R.; Nielsen, J.; Kerkhoven, E. J.

10.1101/321067 — systems biology — Posted on 2018-08-23

789 A Fasciclin 2 functional switch controls organ size in Drosophila

Velasquez, E.; Gomez-Sanchez, J. A.; Donier, E.; Grijota-Martinez, C.; Cabedo, H.; Garcia-Alonso, L. A.

10.1101/356196 — developmental biology — Posted on 2018-08-23

790 GMSE: an R package for generalised management strategy evaluation

Duthie, A. B.; Cusack, J. J.; Jones, I. L.; Minderman, J.; Nilsen, E. B.; Pozo, R. A.; Rakotonarivo, O. S.; Van Moorter, B.; Bunnefeld, N.

10.1101/221432 — ecology — Posted on 2018-08-23

791 Identifying biomarkers of anti-cancer drug synergy using multi-task learning

Aben, N.; de Ruiter, J. R.; Bosdriesz, E.; Kim, Y.; Bounova, G.; Vis, D. J.; Wessels, L. F. A.; Michaut, M.

10.1101/243568 — bioinformatics — Posted on 2018-08-23

792 Production of santalenes and bergamotene in Nicotiana tabacum plants

Yin, J.-L.; Wong, W.-S.

10.1101/398776 — plant biology — Posted on 2018-08-23

793 Altitudinal range-size distribution of breeding birds and environmental factors for the determination of species richness: An empirical test of altitudinal Rapoports rule and rescue effect on a local scale

Kim, J.-Y.; Seo, C.; Hong, S.; Lee, S.; Eo, S. H.

10.1101/398727 — ecology — Posted on 2018-08-23

794 Which osteoarthritic gait features recover following Total Knee Replacement surgery?

Biggs, P.; Whatling, G. M.; Wilson, C.; Metcalfe, A. J.; Holt, C. A.

10.1101/398743 — bioengineering — Posted on 2018-08-23

795 Spatio-temporal variability of soil nutrients and the responses of growth during growth stages of winter wheat in the north of China

Su, B.; Zhao, G.; Dong, C.

10.1101/398701 — scientific communication and education — Posted on 2018-08-23

796 Origins and geographic diversification of African rice (Oryza glaberrima)

Veltman, M.; Flowers, J. M.; van Andel, T. R.; Schranz, M. E.

10.1101/398693 — genomics — Posted on 2018-08-23

797 Quantitative Assessment of Colorectal Cancer Progression: a Comparative Study of Linear and Nonlinear Microscopy Techniques

Adur, J.; Erbes, L.; Bianchi, M.; Ruff, S.; Zeitoune, A.; Izaguirre, M. F.; Cesar, C. L.; Carvahlo, H. F.; Casco, V. H.

10.1101/398719 — cancer biology — Posted on 2018-08-23

798 Sex-specific migration strategies of ospreys (Pandion haliaetus) from Germany

Meyburg, B. U.; Roepke, D.; Meyburg, C.; Van Wijk, R.

10.1101/398735 — animal behavior and cognition — Posted on 2018-08-23

799 Acetate and hypertonic stress stimulate organelle membrane fission using distinct phosphatidylinositol signals

Patel, D.; Brett, C. L.

10.1101/398685 — cell biology — Posted on 2018-08-23

800 Cerebrovascular Injuries Induce Lymphatic Invasion into Brain Parenchyma to Guide Vascular Regeneration in Zebrafish

Chen, J.; He, J.; Yang, Q.; Zhang, Y.; Luo, L.

10.1101/346007 — developmental biology — Posted on 2018-08-23

801 Lesion Attributes Segmentation for Melanoma Detection with Deep Learning

Chen, E. Z.; Dong, X.; Wu, J.; Jiang, H.; Li, X.; Rong, R.

10.1101/381855 — bioinformatics — Posted on 2018-08-23

802 Quantitative mass spectrometry to interrogate proteomic heterogeneity in metastatic lung adenocarcinoma and validate a novel somatic mutation CDK12-G879V

Zhang, X.; Nguyen, K. D.; Rudnick, P.; Roper, N.; Kawaler, E.; Maity, T. K.; Awasthi, S.; Gao, S.; Biswas, R.; Venugopalan, A.; Cultraro, C. M.; Fenyo, D.; Guha, U.

10.1101/398313 — cancer biology — Posted on 2018-08-22

803 Uneven missing data skews phylogenomic relationships within the lories and lorikeets

Smith, B. T.; Mauck, W. M.; Benz, B.; Andersen, M. J.

10.1101/398297 — evolutionary biology — Posted on 2018-08-22

804 Immune genes are hotspots of shared positive selection across birds and mammals

Shultz, A. J.; Sackton, T. B.

10.1101/398362 — evolutionary biology — Posted on 2018-08-22

805 Bacterial predator-prey coevolution selects on virulence-associated prey defenses

Nair, R. R.; Vasse, M.; Wielgoss, S.; Sun, L.; Yu, Y.-T. N.; Velicer, G. J.

10.1101/398495 — evolutionary biology — Posted on 2018-08-22

806 Common behavioral mechanisms underlie C. elegans aggregation and swarming

Ding, S. S.; Schumacher, L. J.; Javer, A. E.; Endres, R. G.; Brown, A. E.

10.1101/398370 — biophysics — Posted on 2018-08-22

807 Investigating functional brain network integrity using a traditional and novel diagnostic system for neurodevelopmental disorders

Dajani, D. R.; Burrows, C. A.; Odriozola, P.; Baez, A.; Nebel, M. B.; Mostofsky, S. H.; Uddin, L. Q.

10.1101/396317 — neuroscience — Posted on 2018-08-22

808 Markerless tracking suggests a tactile sensing role for forelegs of Dolomedes spiders during locomotion

Pullar, K. F.; Paulin, M. G.

10.1101/398479 — animal behavior and cognition — Posted on 2018-08-22

809 Analysis of Polygenic Score Usage and Performance across Diverse Human Populations

Duncan, L.; Shen, H.; Gelaye, B.; Ressler, K.; Feldman, M.; Peterson, R.; Domingue, B.

10.1101/398396 — genetics — Posted on 2018-08-22

810 Hearing through lip-reading: the brain synthesizes features of absent speech

Bourguignon, M.; Baart, M.; Kapnoula, E. C.; Molinaro, N.

10.1101/395483 — neuroscience — Posted on 2018-08-22

811 Drosophila R8 photoreceptor cell subtype specification requires Notch and hibris.

Tan, H.; Fulton, R. E.; Chou, W.-H.; Birkholz, D. A.; Mannino, M. P.; Yamaguchi, D. M.; Britt, S. G.

10.1101/398222 — developmental biology — Posted on 2018-08-22

812 Gene target discovery with network analysis in Toxoplasma gondii

Alonso, A.; Corvi, M.; Diambra, L.

10.1101/397398 — systems biology — Posted on 2018-08-22

813 Allele-specific genome editing using CRISPR-Cas9 causes off-target mutations in diploid yeast

Gorter de Vries, A. R.; Couwenberg, L. G. F.; van den Broek, M.; de la Torre Cortes, P.; ter Horst, J.; Pronk, J. T.; Daran, J.-M. G.

10.1101/397984 — molecular biology — Posted on 2018-08-22

814 Architecture of a bacterial type II secretion system

Chernyatina, A. A.; Low, H. H.

10.1101/397794 — microbiology — Posted on 2018-08-22

815 MSCypher: an integrated database searching and machine learning workflow for multiplexed proteomics.

Kapp, E. A.; Infusini, G.; Zhong, Y.; Dagley, L. F.; Speed, T. P.; Webb, A. I.

10.1101/397257 — bioinformatics — Posted on 2018-08-22

816 Rapid environmental change in games: complications and curiosities

Trimmer, P. C.; Barrett, B. J.; McElreath, R.; Sih, A.

10.1101/397497 — animal behavior and cognition — Posted on 2018-08-22

817 Global identification of functional microRNA::mRNA interactions in Drosophila

Wessels, H.-H.; Lebedeva, S.; Hirsekorn, A.; Mukherjee, N.; Ohler, U.

10.1101/395335 — systems biology — Posted on 2018-08-22

818 Mangrove vegetation inspire a new approach to protect shorelines

Segmaier, R.; Staggs, S.; Palmer, S.

10.1101/397661 — biophysics — Posted on 2018-08-22

819 Optic Nerve Tortuosity and Globe Proptosis in Normal and Glaucoma Subjects

Wang, X.; Rumpel, H.; Baskaran, M.; Tun, T. A.; Strouthidis, N.; Perera, S. A.; Nongpiur, M. E.; Lim, W. E. H.; Aung, T.; Milea, D.; Girard, M. J. A.

10.1101/397570 — pathology — Posted on 2018-08-22

820 Subclinical infection of macaques and baboons with a baboon simartevirus

Buechler, C.; Semler, M.; Baker, D. A.; Newman, C.; Cornish, J. P.; Chavez, D.; Guerra, B.; Lanford, R.; Brasky, K.; Kuhn, J. H.; Johnson, R. F.; O'Connor, D. H.; Bailey, A.

10.1101/397430 — microbiology — Posted on 2018-08-22

821 RNA-binding protein A1CF modulates plasma triglyceride levels through posttranscriptional regulation of stress-induced VLDL secretion

Lin, J.; Conlon, D. M.; Wang, X.; Von Nostrand, E.; Robano, I.; Park, Y.; Strong, A.; Radmanesh, B.; Barash, Y.; Rader, D. J.; Yeo, G. W.; Musunuru, K.

10.1101/397554 — genomics — Posted on 2018-08-22

822 Songs in the understory and colors in the canopy: habitat structure leads to different avian communication strategies in a tropical montane forest

Laverde-R., O.; Cadena, C. D.

10.1101/393595 — evolutionary biology — Posted on 2018-08-22

823 Pollinator size and its consequences: Predictive allometry for pollinating insects

Kendall, L. K.; Rader, R.; Gagic, V.; Cariveau, D. P.; Albrecht, M.; Baldock, K. C. R.; Freitas, B. M.; Hall, M.; Holzschuh, A.; Molina, F. P.; Morten, J. M.; Pereira, J. S.; Portman, Z. M.; Roberts, S. P. M.; Rodriguez, J.; Russo, L.; Sutter, L.; Vereecken, N. J.; Bartomeus, I.

10.1101/397604 — ecology — Posted on 2018-08-22

824 Early Life Trauma Predicts Affective Phenomenology and the Effects are Partly Mediated by Staging Coupled with Lowered Lipid-Associated Antioxidant Defences.

Maes, M.; Congio, A.; Brum, J.; Bonifacio, K.; Barbosa, D.; Vargas, H.; Morris, G.; Puri, B.; Michelin, A. P.; Nunes, S.

10.1101/397711 — neuroscience — Posted on 2018-08-22

825 An Automated Behavioral Apparatus to Assess Distal Forelimb Function in Non-Human Primates

Totten, D.; Novik, L.; Christe, K.; Lemoy, M.-J.; Roberts, J.; Carmena, J.; Morecraft, R.; Ganguly, K.

10.1101/396572 — neuroscience — Posted on 2018-08-22

826 Transcription activity contributes to the activation of non-constitutive origins to maintain the robustness of S phase duration in African trypanosomes

da Silva, M.; Cayres-Silva, G. R.; Vitarelli, M. O.; Marin, P. A.; Hiraiwa, P. M.; Araujo, C. B.; Avila, A. R.; Reis, M. S.; Elias, M. C.

10.1101/398016 — molecular biology — Posted on 2018-08-22

827 Arnav: Site specific error models to identify variants in RNA

Ramu, A.; Conrad, D.

10.1101/397539 — genomics — Posted on 2018-08-22

828 Relaxed constraint and thermal desensitization of the cold-sensing ion channel TRPM8 in mammoths

Chigurapati, S.; Miller, W.; Lynch, V. J.

10.1101/397356 — evolutionary biology — Posted on 2018-08-22

829 A 3-fold kernel approach for characterizing Late Onset Alzheimer’s Disease

Squillario, M.; Tomasi, F.; Tozzo, V.; Barla, A.; Uberti, D.

10.1101/397760 — bioinformatics — Posted on 2018-08-22

830 Weakly supervised classification of rare aortic valve malformations using unlabeled cardiac MRI sequences

Fries, J. A.; Varma, P.; Chen, V. S.; Xiao, K.; Tejeda, H.; Saha, P.; Dunnmon, J.; Chubb, H.; Maskatia, S.; Fiterau, M.; Delp, S.; Ashley, E.; Re, C.; Priest, J.

10.1101/339630 — bioinformatics — Posted on 2018-08-22

831 Learning 2-in-1: towards integrated EEG-fMRI-neurofeedback

Perronnet, L.; Lecuyer, A.; Mano, M.; Clerc, M.; Lotte, F.; Barillot, C.

10.1101/397729 — bioengineering — Posted on 2018-08-22

832 A draft reference genome sequence for Scutellaria baicalensis Georgi

Zhao, Q.; Yang, J.; Liu, J.; Cui, M.; Fang, Y.; Qiu, W.; Shang, H.; Xu, Z.; Wei, Y.; Yang, L.; Hu, Y.; Chen, X.-Y.; Martin, C.

10.1101/398032 — plant biology — Posted on 2018-08-22

833 Gut microbial features can predict host phenotype response to protein deficiency

Navarro, G.; Sharma, A.; Dugas, L. R.; Forrester, T.; Gilbert, J. A.; Layden, B. T.

10.1101/398248 — physiology — Posted on 2018-08-22

834 White matter aberrations and age-related trajectories in patients with schizophrenia and bipolar disorder revealed by diffusion tensor imaging

Toennesen, S.; Kaufmann, T.; Doan, N. T.; Alnaes, D.; Cordova-Palomera, A.; van der Meer, D.; Rokicki, J.; Moberget, T.; Gurholt, T. P.; Haukvik, U. K.; Ueland, T.; Lagerberg, T. V.; Agartz, I.; Andreassen, O. A.; Westlye, L. T.

10.1101/395889 — neuroscience — Posted on 2018-08-22

835 Two lytic bacteriophages that depend on the Escherichia coli multi-drug efflux gene tolC and differentially affect bacterial growth and selection

Burmeister, A. R.; Bender, R. G.; Fortier, A.; Lessing, A. J.; Chan, B. K.; Turner, P. E.

10.1101/397695 — microbiology — Posted on 2018-08-22

836 Systematic evaluation of the causal relationship between DNA methylation and C-reactive protein

Walton, E.; Hemani, G.; Dehghan, A.; Relton, C.; Davey Smith, G.

10.1101/397836 — genetics — Posted on 2018-08-22

837 GxEMM: Extending linear mixed models to general gene-environment interactions

Dahl, A.; Cai, N.; Flint, J.; Zaitlen, N.

10.1101/397638 — genetics — Posted on 2018-08-22

838 Stochastic population dynamics driven by mutant interactors

Park, H. J.; Pichugin, Y.; Huang, W.; Traulsen, A.

10.1101/397810 — evolutionary biology — Posted on 2018-08-22

839 Empirical analysis and modelling of Argos Doppler location errors in Romania

Rozylowicz, L.; Bodescu, F. P.; Ciocanea, C. M.; Gavrilidis, A. A.; Manolache, S.; Matache, M. L.; Miu, I. V.; Moale, C.; Nita, A.; Popescu, V. D.

10.1101/397364 — ecology — Posted on 2018-08-22

840 A divergent kinase lacking the glycine-rich loop regulates membrane ultrastructure of the Toxoplasma parasitophorous vacuole

Beraki, T.; Hu, X.; Broncel, M.; Young, J. C.; O'Shaughnessy, W. J.; Borek, D. M.; Treeck, M.; Reese, M. L.

10.1101/397489 — cell biology — Posted on 2018-08-22

841 Zero-preserving imputation of scRNA-seq data using low-rank approximation

Linderman, G. C.; Zhao, J.; Kluger, Y.

10.1101/397588 — bioinformatics — Posted on 2018-08-22

842 Understanding the killing mechanism of action by virus-infected yeasts

Sheppard, S.; Dikicioglu, D.

10.1101/398099 — systems biology — Posted on 2018-08-22

843 The Rhizoctonia solani LysM and RlpA-like effector proteins contribute to virulence suppressing chitin-triggered immunity and hypersensitive response

Dolfors, F.; Holmquist, L.; Moschou, P.; Dixelius, C.; Tzelepis, G.

10.1101/395582 — plant biology — Posted on 2018-08-22

844 Speaker-normalized vowel representations in the human auditory cortex

Sjerps, M. J.; Fox, N. P.; Johnson, K.; Chang, E. F.

10.1101/397026 — neuroscience — Posted on 2018-08-22

845 The Effect of Visual Capture Towards Subjective Embodiment Within the Full Body Illusion

Carey, M.; Crucianelli, L.; Preston, C.; Fotopoulou, A.

10.1101/397943 — neuroscience — Posted on 2018-08-22

846 Reward revaluation biases hippocampal sequence content away from the preferred outcome

Carey, A. A.; Tanaka, Y.; van der Meer, M.

10.1101/397950 — neuroscience — Posted on 2018-08-22

847 TCF7L2 Regulation of GATA6-dependent and -Independent Vascular Smooth Muscle Cell Plasticity and Intimal Hyperplasia

Mani, A.; Srivastava, R.; Xie, Y.; Li, N.; Bhat, N.; Hong, L.; Esteghamat, S.; Adeniran, A.; Geirsson, A.; Zhang, J.; Ge, G.; Nobrega, M.; Martin, K. A.; Rolyan, H.

10.1101/397851 — molecular biology — Posted on 2018-08-22

848 Neuraminidase Inhibition Contributes to Influenza A Virus Neutralization by Anti-Hemagglutinin Stem Antibodies

Kosik, I.; Angeletti, D.; Gibbs, J. S.; Angel, M.; Takeda, K.; Kosikova, M.; Nair, V.; Hickman, H. D.; Xie, H.; Brooke, C. C.; Yewdell, J. W.

10.1101/397976 — microbiology — Posted on 2018-08-22

849 A novel function of Galactomyces candidum in highly efficient ammonia nitrogen removal from low C:N wastewater

Liu, W.; Yang, L.; Li, X.; Liu, H.; Zeng, G.; Li, H.; Chen, Z.

10.1101/397687 — microbiology — Posted on 2018-08-22

850 Fitness Landscape of the Fission Yeast Genome

Grech, L.; Jeffares, D. C.; Sadee, C. Y.; Rodriguez-Lopez, M.; Bitton, D. A.; Hoti, M.; Biagosch, C.; Aravani, D.; Speekenbrink, M.; Illingworth, C. J. R.; Schiffer, P. H.; Pidoux, A. L.; Tong, P.; Tallada, V. A.; Allshire, R.; Levin, H. L.; Bahler, J.

10.1101/398024 — genomics — Posted on 2018-08-22

851 Mining ancient microbiomes using selective enrichment of damaged DNA molecules

Weiss, C. L.; Gansauge, M.-T.; Aximu-Petri, A.; Meyer, M.; Burbano, H. A.

10.1101/397927 — genomics — Posted on 2018-08-22

852 RNA sequencing of the in vivo human herpesvirus 6B transcriptome to identify targets for clinical assays distinguishing between latent and active infections

Hill, J. A.; Ikoma, M.; Zerr, D. M.; Basom, R. S.; Peddu, V.; Huang, M.-L.; Hall Sedlak, R.; Jerome, K.; Boeckh, M.; Barcy, S.

10.1101/397679 — genomics — Posted on 2018-08-22

853 A human cell model of cardiac pathophysiological valvulogenesis

Neri, T.; Hiriart, E.; Van Vliet, P.; Faure, E.; Norris, R.; Farhat, B.; Lefrancois, J.; Moore-Morris, T.; Zaffran, S.; Faustino, R.; Zambon, A.; Devisgnes, J.-P.; Salgado, D.; Sugi, Y.; Levine, R.; de la Pompa, J. L.; Terzic, A.; Evans, S.; Markwald, R.; Puceat, m.

10.1101/397422 — developmental biology — Posted on 2018-08-22

854 Significant antitumour effect of an antibody against TMEM180, a new cancer-specific molecule

Yasunaga, M.; Saijou, S.; Hanaoka, S.; Anzai, T.; Tsumura, R.; Matsumura, Y.

10.1101/397844 — cancer biology — Posted on 2018-08-22

855 Revealing evolutionary constraints on proteins through sequence analysis

Wang, S.-W.; Bitbol, A.-F.; Wingreen, N. S.

10.1101/397521 — biophysics — Posted on 2018-08-22

856 OMA standalone: orthology inference among public and custom genomes and transcriptomes

Altenhoff, A. M.; Levy, J.; Zarowiecki, M.; Tomiczek, B.; Warwick Vesztrocy, A.; Dalquen, D.; Müller, S.; Telford, M.; Glover, N.; Dylus, D.; Dessimoz, C.

10.1101/397752 — bioinformatics — Posted on 2018-08-22

857 Gene Correction for SCID-X1 in Long-Term Hematopoietic Stem Cells

Pavel-Dinu, M.; Wiebking, V.; Dejene, B. T.; Srifa, W.; Mantri, S.; Nicolas, C.; Lee, C.; Bao, G.; Kildebeck, E. J.; Punjya, N.; Sindhu, C.; Inlay, M. A.; Saxena, N.; DeRavin, S. S.; Malech, H.; Roncarolo, M. G.; Weinberg, K. I.; Porteus, M.

10.1101/397463 — bioengineering — Posted on 2018-08-22

858 LION/web: a web-based ontology enrichment tool for lipidomic data analysis

Molenaar, M.; Jeucken, A.; Wassenaar, T. A.; van de Lest, C. H. A.; Brouwers, J. F.; Helms, J. B.

10.1101/398040 — biochemistry — Posted on 2018-08-22

859 The geometry of dependence: solitary bee larvae prioritize carbohydrate over protein in parentally provided pollen

Austin, A. J.; Gilbert, J. D. J.

10.1101/397802 — animal behavior and cognition — Posted on 2018-08-22

860 Hypomethylation of STAT1 and HLA-DRB1 is associated with type-I interferon-dependent HLA-DRB1 expression in lupus CD8+ T cells

Miller, S.; Coit, P.; Gensterblum-Miller, E.; Renauer, P.; Kilian, N. C.; Schonfeld, M.; Tsou, P.-S.; Sawalha, A. H.

10.1101/398081 — immunology — Posted on 2018-08-22

861 Synthetic and genomic regulatory elements reveal aspects of cis-regulatory grammar in Mouse Embryonic Stem Cells

King, D. M.; Maricque, B. B.; Cohen, B. A.

10.1101/398107 — genomics — Posted on 2018-08-22

862 A de novo EDA-variant in a litter of shorthaired standard Dachshunds with X-linked hypohidrotic ectodermal dysplasia

Vasiliadis, D.; Hewicker-Trautwein, M.; Klotz, D.; Fehr, M.; Ruseva, S.; Arndt, J.; Metzger, J.; Distl, O.

10.1101/397372 — genetics — Posted on 2018-08-22

863 High-order epistasis in catalytic power of dihydrofolate reductase gives rise to a rugged fitness landscape in the presence of trimethoprim selection

Tamer, Y. T.; Gaszek, I. K.; Abdizadeh, H.; Batur, T.; Reynolds, K.; Atilgan, A. R.; Atilgan, C.; Toprak, E.

10.1101/398065 — evolutionary biology — Posted on 2018-08-22

864 Actomyosin-driven tension at compartmental boundaries orients cell division independently of cell geometry in vivo

Scarpa, E.; Finet, C.; Blanchard, G.; Sanson, B.

10.1101/397893 — developmental biology — Posted on 2018-08-22

865 PHASE TRANSITIONED NUCLEAR OSKAR PROMOTES CELL DIVISION OF DROSOPHILA PRIMORDIAL GERM CELLS

Kistler, K. E.; Trcek, T.; Hurd, T. R.; Chen, R.; Liang, F.-X.; Sall, J.; Kato, M.; Lehmann, R.

10.1101/397992 — cell biology — Posted on 2018-08-22

866 Combinatorial recognition of clustered RNA elementsby a multidomain RNA-binding protein, IMP3

Schneider, T.; Hung, L.-H.; Aziz, M.; Wilmen, A.; Thaum, S.; Wagner, J.; Janowski, R.; Muller, S.; Huttelmaier, S.; Niessing, D.; Sattler, M.; Schlundt, A.; Bindereif, A.

10.1101/398008 — molecular biology — Posted on 2018-08-22

867 Modelling mitosis with multiple phenotypes: relation to Haeckel’s recapitulation law

Alexandrov, Y.

10.1101/253203 — physiology — Posted on 2018-08-22

868 Genetic screen suggests an alternative mechanism for azide-mediated inhibition of SecA

Jamshad, M.; Chandler, R.; Yule, J.; Robinson, A.; Alam, F.; Dunne, K.; Nabi, N.; Henderson, I. R.; Huber, D.

10.1101/173039 — microbiology — Posted on 2018-08-22

869 Intracellular signaling through the comRS system in Streptococcus mutans genetic competence

Underhill, S. A. M.; Shields, R. C.; Kaspar, J. R.; Haider, M.; Burne, R. A.; Hagen, S. J.

10.1101/291088 — microbiology — Posted on 2018-08-22

870 Intron-mediated enhancement boosts Rtn4 circRNA expression: A robust method for exploring circRNA function

Mo, D.; Li, X.; Cui, D.; Vollmar, J.-F.

10.1101/257105 — biochemistry — Posted on 2018-08-22

871 The C-terminal tail of the bacterial translocation ATPase SecA modulates its activity

Jamshad, M.; Knowles, T.; White, S.; Ward, D.; Mohammed, F.; Rahman, K. F.; Hughes, G. W.; Kramer, G.; Bukau, B.; Huber, D.

10.1101/389460 — biochemistry — Posted on 2018-08-22

872 Continued circulation, recombination and evolution of the ancient subcontinent lineage despite predominance of the recent arctic-like lineage rabies viruses (RABV) in India

Kuchipudi, S. V.; Deventhiran, J.; Srinivasan, B.; Seeralan, M.; Kanagaraj, V.; Raju, S.; Kathaperumal, K.; Nissly, R. H.; Kasibhatla, S. M.; Kale, M. M.; Kulkarni-Kale, U.

10.1101/398180 — microbiology — Posted on 2018-08-22

873 Effect of Platelet-activating factor on barrier function of ARPE-19 cells

Zhang, F.; Liu, L.; Zhang, H.; Liu, Z.-L.

10.1101/398131 — cell biology — Posted on 2018-08-22

874 Agent-Based Modeling Predicts HDL-independent Pathway of Removal of Excess Surface Lipids from Very Low Density Lipoprotein

Paalvast, Y.; Kuivenhoven, J. A.; Bakker, B. M.; Groen, A. K.

10.1101/398164 — systems biology — Posted on 2018-08-22

875 Dimethylarsenic acid (DMA) accumulation positively correlates with realgar-induced subchronic toxicity in rats

YI, Y.; Gao, S.; Xia, J.; Zhao, Y.; Li, C.; Zhang, Y.; Wang, L.; Pan, C.; Liu, S.; Han, J.; Liang, A.; Ji, S.

10.1101/398206 — pharmacology and toxicology — Posted on 2018-08-22

876 Reversible temporally-specific inhibition of muscle using a light-activated chloride channel

Gorini, C.; Iyer, S.; Vyas, S.; Ramakrishnan, C.; Deisseroth, K.; Delp, S.

10.1101/398156 — neuroscience — Posted on 2018-08-22

877 Impact of two neighbouring ribosomal protein clusters on biogenesis factor binding and assembly of yeast late small ribosomal subunit precursors

Linnemann, J.; Pöll, G.; Jakob, S.; Ferreira-Cerca, S.; Griesenbeck, J.; Tschochner, H.; Milkereit, P.

10.1101/398149 — molecular biology — Posted on 2018-08-22

878 Assessment of abduction movement in older people with painful shoulder: an analysis based on inertial sensors

Roldan-Jimenez, C.; Martin-Martin, J.; Bennett, P.; McPhail, S.; Vargas, A. C.; Kerr, G.

10.1101/398123 — bioengineering — Posted on 2018-08-22

879 Molecular Mechanisms Governing Shade Responses in Maize

Shi, Q.; Kong, F.; Zhang, H.; Jiang, Y.; Heng, S.; Liang, R.; Liu, J.; Lu, X.; Li, P.; Li, G.

10.1101/397596 — plant biology — Posted on 2018-08-22

880 Occurrence of non-western magic in the European brain

Koten, J. W.; Schueppen, A.; Kumar, V.; Wood, G.

10.1101/395285 — neuroscience — Posted on 2018-08-22

881 Cell Diameter in Bacillus subtilis is Determined by the Opposing Actions of Two Distinct Cell Wall Synthetic Systems

Dion, M.; Kapoor, M.; Sun, Y.; Wilson, S.; Ryan, J.; Vigouroux, A.; van Teeffelen, S.; Oldenbourg, R.; Garner, E. C.

10.1101/392837 — microbiology — Posted on 2018-08-22

882 Effects of Attentional Bias Modification on Residual Symptoms in depression. A Randomized Controlled Trial.

Jonassen, R.; Harmer, C. J.; Hilland, E.; Maglanoc, L. A.; Kraft, B.; Browning, M.; Stiles, T. C.; Haaland, V. O.; Berge, T.; Landro, N. I.

10.1101/318279 — clinical trials — Posted on 2018-08-22

883 Effect of de novo transcriptome assembly on transcript quantification

Hsieh, P.-H.; Oyang, Y.-J.; Chen, C.-Y.

10.1101/380998 — bioinformatics — Posted on 2018-08-22

884 The SUMO conjugation complex self-assembles into nuclear bodies independent of SIZ1 and COP1

Mazur, M. J.; Kwaaitaal, M.; Arroyo Mateos, M.; Maio, F.; Ramachandra, K. K.; Prins, M.; van den Burg, H. A.

10.1101/393272 — plant biology — Posted on 2018-08-22

885 Genotyping and epidemiological metadata provides new insights into population structure of Xanthomonas isolated from walnut trees

Fernandes, C.; Albuquerque, P.; Cruz, L.; Tavares, F.

10.1101/397703 — microbiology — Posted on 2018-08-22

886 Transcriptional heterogeneity of Cryptococcus gattii VGII compared with non-VGII lineages underpins key pathogenicity pathways

Farrer, R. A.; Ford, C. B.; Rhodes, J.; Delorey, T.; May, R. C.; Fisher, M.; Cloutman-Green, E.; Balloux, F.; Cuomo, C. A.

10.1101/396796 — genomics — Posted on 2018-08-22

887 Genome Scale Epigenetic Profiling Reveals Five Distinct Subtypes of Colorectal Cancer

Fennell, L.; Dumenil, T.; Hartel, G.; Nones, K.; Bond, C.; Mckeone, D.; Bowdler, L.; Montgomery, G.; Wockner, L.; Klein, K.; Hoffmann, I.; Patch, A.-M.; Kazakoff, S.; Pearson, J.; Waddell, N.; Wirapati, P.; Lochhead, P.; Imamura, Y.; Ogino, S.; Shao, R.; Tejpar, S.; Leggett, B.; Whitehall, V.

10.1101/397620 — genomics — Posted on 2018-08-22

888 A Multiplexed DNA FISH strategy for Assessing Genome Architecture in C. elegans

Fields, B. D.; Nguyen, S. C.; Nir, G.; Kennedy, S.

10.1101/397471 — cell biology — Posted on 2018-08-22

889 Cancer archetypes co-opt and adapt the transcriptional programs of existing cellular states

Baron, M.; Kim, I. S.; Moncada, R.; Yan, Y.; Campbell, N. R.; White, R. M.; Yanai, I.

10.1101/396622 — cancer biology — Posted on 2018-08-22

890 FACT and Ubp10 collaborate to modulate H2B deubiquitination and nucleosome dynamics

Nune, M.; Morgan, M. T.; Connell, Z.; McCullough, L.; Jbara, M.; Sun, H.; Brik, A.; Formosa, T.; Wolberger, C.

10.1101/397653 — biochemistry — Posted on 2018-08-22

891 Fast Batch Alignment of Single Cell Transcriptomes Unifies Multiple Mouse Cell Atlases into an Integrated Landscape

Park, J.-E.; Polanski, K.; Meyer, K.; Teichmann, S. A.

10.1101/397042 — bioinformatics — Posted on 2018-08-22

892 tmap: topological analysis of population-scale microbiome data

Liao, T.; Wei, Y.; Luo, M.; Zhao, G.; Zhou, H.

10.1101/396960 — bioinformatics — Posted on 2018-08-22

893 The saturation gap: a simple transformation of oxygen saturation using virtual shunt

Zhou, G.; Karlen, W.; Brant, R.; Wiens, M.; Ansermino, J. M.

10.1101/391292 — bioengineering — Posted on 2018-08-22

894 Cyclin D-Cdk4,6 drives cell cycle progression via the retinoblastoma protein’s C-terminal helix

Topacio, B. R.; Zatulovskiy, E.; Cristea, S.; Xie, S.; Tambo, C. S.; Rubin, S. M.; Sage, J.; Koivomägi, M.; Skotheim, J. M.

10.1101/397448 — cell biology — Posted on 2018-08-21

895 Seeing in the dark: Vectashield quenches Alexa Fluor 647 fluorescence, but does not hinder dSTORM imaging

Arsic, A.; Stajkovic, N.; Spiegel, R.; Nikic-Spiegel, I.

10.1101/393264 — biophysics — Posted on 2018-08-21

896 The neuronal basis of insect stereopsis

Rosner, R.; von Hadeln, J.; Tarawneh, G.; Read, J.

10.1101/395939 — neuroscience — Posted on 2018-08-21

897 Bariatric surgery changes gut microbiota composition independent of operation type

10.1101/395657 — microbiology — Posted on 2018-08-21

898 Metformin Intervention Prevents Cardiac Dysfunction in a Murine Model of Adult Congenital Heart Disease

Costa, M. W.; Wilmanns, J. C.; Pandey, R.; Hon, O.; Chandran, A.; Schilling, J. M.; Wu, Q.; Cagnone, G.; Bais, P.; Phillip, V.; Kocalis, H.; Archer, S. K.; Pearson, J. T.; Ramialison, M.; Heineke, J.; Patel, H. H.; Rosenthal, N. A.; Furtado, M. B.

10.1101/396416 — genetics — Posted on 2018-08-21

899 RNAi screen in Tribolium reveals involvement of F-BAR proteins in myoblast fusion and visceral muscle morphogenesis in arthropods

Schultheis, D.; Schwirz, J.; Frasch, M.

10.1101/397232 — developmental biology — Posted on 2018-08-21

900 A Tumor Suppressor-Regulated Cell Cycle Derived Gene Signature Is Prognostic Of Recurrence Risk In Prostate Cancer

Georgescu, C.; Corbin, J. M.; Thivibilliers, S.; Webb, Z. D.; Zhao, Y. D.; Koster, J.; Fung, K.-M.; Asch, A. S.; Wren, J. D.; Ruiz Echevarria, M. J.

10.1101/397331 — cancer biology — Posted on 2018-08-21

901 Confidence in predicted position error explains saccadic decisions during pursuit

Coutinho, J. D.; Lefevre, P.; Blohm, G.

10.1101/396788 — neuroscience — Posted on 2018-08-21

902 Starvation resistance is associated with developmentally specified changes in sleep, feeding and metabolic rate

Slocumb, M. E.; Kerbs, A.; Kayser, M. S.; Brown, E. B.; Szuperak, M.; Gibbs, A. G.; Keene, A.

10.1101/397455 — neuroscience — Posted on 2018-08-21

903 Robust and clinically relevant prediction of response to anti-cancer drugs via network integration of molecular profiles

Franco, M.; Jeggari, A.; Peuget, S.; Böttger, F.; Selivanova, G.; Alexeyenko, A.

10.1101/301838 — cancer biology — Posted on 2018-08-21

904 How to design an optimal sensor network for the unfolded protein response

Stroberg, W.; Aktin, H.; Savir, Y.; Schnell, S.

10.1101/396614 — systems biology — Posted on 2018-08-21

905 Genetic variation in a complex polyploid: unveiling the dynamic allelic features of sugarcane

Sforca, D. A.; Vautrin, S.; Cardoso-Silva, C. B.; Mancini, M. C.; Cruz, M. V. R.; Pereira, G. d. S.; Conte, M.; Bellec, A.; Dahmer, N.; Fourment, J.; Rodde, N.; Van-Sluys, M.-A.; Vicentini, R.; Garcia, A. A. F.; Forni-Martins, E. R.; Carneiro, M. S.; Hoffmann, H. P.; Pinto, L. R.; Landell, M. G. d. A.; Vincentz, M.; Berges, H.; Souza, A. P.

10.1101/361089 — plant biology — Posted on 2018-08-21

906 Individual variation in longitudinal postnatal development of the primate brain

Ball, G.; Seal, M. L.

10.1101/396887 — neuroscience — Posted on 2018-08-21

907 A spike timing-dependent plasticity rule for single, clustered and distributed dendritic spines

Tazerart, S.; Mitchell, D. E.; Miranda-Rottmann, S.; Araya, R.

10.1101/397323 — neuroscience — Posted on 2018-08-21

908 Cross-scale dynamics and the evolutionary emergence of infectious diseases

Schreiber, S. J.; Ke, R.; Loverdo, C.; Park, M.; Ahsan, P.; Lloyd-Smith, J. O.

10.1101/066688 — epidemiology — Posted on 2018-08-21

909 Expected differences in diversity and rarity between communities containing sexually versus asexually reproducing taxa

Herren, C.

10.1101/397174 — ecology — Posted on 2018-08-21

910 A Latent Allocation Model for the Analysis of Microbial Composition and Disease

Abe, K.; Hirayama, M.; Ohno, K.; Shimamura, T.

10.1101/396903 — bioinformatics — Posted on 2018-08-21

911 Increased rates of genomic mutation in a biofilm co-culture model of P. aeruginosa and S. aureus

Frapwell, C. J.; Howlin, R. P.; Soren, O.; McDonagh, B. T.; Duignan, C. M.; Allan, R. N.; Horswill, A. R.; Stoodley, P.; Hu, Y.; Coates, A. R.; Webb, J. S.

10.1101/387233 — microbiology — Posted on 2018-08-21

912 A comprehensive genomics solution for HIV surveillance and clinical monitoring in a global health setting

10.1101/397083 — genomics — Posted on 2018-08-21

913 Blood, sweat and tears: a review of non-invasive DNA sampling

Lefort, M.-C.; Cruickshank, R. H.; Descovich, K.; Adams, N. J.; Barun, A.; Emami-Khoyi, A.; Ridden, J.; Smith, V. R.; Sprague, R.; Waterhouse, B.; Boyer, S.

10.1101/385120 — ecology — Posted on 2018-08-21

914 tmap: topological analysis of population-scale microbiome data

Liao, T.; Wei, Y.; Luo, M.; Zhao, G.; Zhou, H.

10.1101/396960 — bioinformatics — Posted on 2018-08-21

915 Plug-and-Play Metabolic Transducers Expand the Chemical Detection Space of Cell-Free Biosensors

Voyvodic, P. L.; Pandi, A.; Koch, M.; Faulon, J.-L.; Bonnet, J.

10.1101/397315 — synthetic biology — Posted on 2018-08-21

916 Senescent, dysfunctional human cardiac progenitor cells (CPCs) accumulate in the aged heart and elimination of senescent cells enhances CPC activation and cardiomyocyte proliferation in aged mice

Lewis-McDougall, F. C.; Ruchaya, P. J.; Domenjo-Vila, E.; Teoh, T. S.; Prata, L.; Cottle, B. J.; Clark, J. E.; Punjabi, P. P.; Awad, W.; Torella, D.; Tchkonia, T.; Kirkland, J. L.; Ellison-Hughes, G. M.

10.1101/397216 — physiology — Posted on 2018-08-21

917 Altered Bacteria-Fungi Inter-Kingdom Network in Gut of Ankylosing Spondylitis Patients

li, M.; Dai, B.; Tang, Y.; Lei, L.; Li, N.; Liu, C.; Ge, T.; Zhang, L.; Xu, Y.; Hu, Y.; Li, P.; Zhang, Y.; Yuan, J.; Li, X.

10.1101/396812 — microbiology — Posted on 2018-08-21

918 Defining the core essential genome of Pseudomonas aeruginosa

Poulsen, B. E.; Yang, R.; Clatworthy, A. E.; White, T.; Osmulski, S. J.; Li, L.; Penaranda, C.; Shoresh, N.; Hung, D. T.

10.1101/396689 — microbiology — Posted on 2018-08-21

919 Little variation in the morphology of the atria across 13 orders of birds

Kroneman, J.; Faber, J.; Wolschrijn, C.; Christoffels, V.; Jensen, B.

10.1101/397034 — evolutionary biology — Posted on 2018-08-21

920 DocClustering: An implementation of the novel PS-Document Clustering algorithm

Doerpinghaus, J.; Schaaf, S.; Jacobs, M.

10.1101/397133 — bioinformatics — Posted on 2018-08-21

921 Systems therapeutics analyses identify genomic signatures defining responsiveness to allopurinol and combination therapy for lung cancer

Tavassoly, I.; Hu, Y.; Zhao, S.; Mariottini, C.; Boran, A.; Chen, Y.; Li, L.; Tolentino, R. E.; Jayaraman, G.; Goldfarb, J.; Gallo, J.; Iyengar, R.

10.1101/396697 — systems biology — Posted on 2018-08-21

922 Mutual synchronization pattern as a complementary indicator of the short-term blood pressure - heart rate feedback regulation activity

Pyko, N. S.; Pyko, S. A.; Markelov, O. A.; Mamontov, O. V.; Bogachev, M.

10.1101/397208 — physiology — Posted on 2018-08-21

923 Farmers perceptions on the causes of cassava root bitterness in konzo-affected areas of Mtwara Region, Tanzania

Imakumbili, M. L. E.; Semu, E.; Semoka, J. M. R.; Abass, A.; Mkamilo, G.

10.1101/397018 — pharmacology and toxicology — Posted on 2018-08-21

924 Regional low-frequency oscillations in human rapid-eye movement sleep

Bernardi, G.; Betta, M.; Ricciardi, E.; Pietrini, P.; Tononi, G.; Siclari, F.

10.1101/397224 — neuroscience — Posted on 2018-08-21

925 Altered dendritic spine function and integration in a mouse model of Fragile X Syndrome

Booker, S. A.; Domanski, A. P.; Dando, O. R.; Jackson, A. D.; Isaac, J. T.; Hardingham, G. E.; Wyllie, D. J.; Kind, P. C.

10.1101/396986 — neuroscience — Posted on 2018-08-21

926 The role of the fornix in human navigational learning

Hodgetts, C. J.; Stefani, M.; Williams, A. N.; Kolarik, B. S.; Yonelinas, A. P.; Ekstrom, A. D.; Lawrence, A. D.; Zhang, J.; Graham, K. S.

10.1101/391888 — neuroscience — Posted on 2018-08-21

927 Pyrite formation from FeS and H2S is mediated by a novel type of microbial energy metabolism

Thiel, J.; Byrne, J.; Kappler, A.; Schink, B.; Pester, M.

10.1101/396978 — microbiology — Posted on 2018-08-21

928 A highly conserved complete accessory Escherichia coli type III secretion system 2 is widespread in bloodstream isolates of the ST69 lineage

Evans, T. J.; Fox, S.; Goswami, C.; Holden, M. T.; Connolly, J. P.; Roe, A. J.; Connor, M.; Leanord, A.

10.1101/396804 — microbiology — Posted on 2018-08-21

929 Mitochondrial DNA and their nuclear copies in parasitic wasp Pteromalus puparum: A comparative analysis in Chalcidoidea

Yan, Z.; Fang, Q.; Tian, Y.; Wang, F.; Chen, X.; Werren, J. H.; Ye, G.

10.1101/396911 — genomics — Posted on 2018-08-21

930 A Multimodal Adaptive Super-Resolution and Confocal Microscope

Valiya Peedikakkal, L.; Furley, A.; Cadby, A. J.

10.1101/397273 — biophysics — Posted on 2018-08-21

931 ENIGMA: An Enterotype-Like Unigram Mixture Model for Microbial Association Analysis

Abe, K.; Hirayama, M.; Ohno, K.; Shimamura, T.

10.1101/397091 — bioinformatics — Posted on 2018-08-21

932 Fast Batch Alignment of Single Cell Transcriptomes Unifies Multiple Mouse Cell Atlases into an Integrated Landscape

Park, J.-E.; Polanski, K.; Meyer, K.; Teichmann, S. A.

10.1101/397042 — bioinformatics — Posted on 2018-08-21

933 Divine: Prioritizing Genes for Rare Mendelian Disease in Whole Exome Sequencing Data

Hong, C.; Clemenceau, J. R.; Yeu, Y.; Hwang, T. H.

10.1101/396655 — bioinformatics — Posted on 2018-08-21

934 Long fragments achieve lower base quality in Illumina paired-end sequencing

Tan, G.; Opitz, L.; Schlapbach, R.; Rehrauer, H.

10.1101/397158 — bioinformatics — Posted on 2018-08-21

935 Marker-based watershed transform method for fully automatic mandibular segmentation from low-dose CBCT images

Fan, Y.; Beare, R.; Matthews, H.; Schneider, P.; Kilpatrick, N.; Clement, J.; Claes, P.; Penington, A.; Adamson, C.

10.1101/397166 — bioinformatics — Posted on 2018-08-21

936 A better way to define and describe Morlet wavelets for time-frequency analysis

Cohen, M. X.

10.1101/397182 — neuroscience — Posted on 2018-08-21

937 Screening of antimicrobial activity and polyketide synthase gene identification from the Actinomycetes isolates

SRIVASTAV, A. V.

10.1101/396846 — microbiology — Posted on 2018-08-21

938 Dynamin is required for efficient cytomegalovirus maturation and envelopment

Hasan, M. H.; Davis, L.; Bollavarapu, R. K.; Mitra, D.; Parmar, R. C.; Tandon, R.

10.1101/396820 — microbiology — Posted on 2018-08-21

939 Streptomyces volatile compounds influence exploration and microbial community dynamics by altering iron availability

Jones, S. E.; Pham, C. A.; McKillip, J.; Zambri, M.; Carlson, E. E.; Elliot, M.

10.1101/396606 — microbiology — Posted on 2018-08-21

940 Survival of selected lactic acid bacteria isolated from pineapple waste in refrigerated pineapple juices

Wen Fang Wu, J.; Uribe, L.; WingChing-Jones, R.; Usaga, J.; Barboza, N.

10.1101/396838 — bioengineering — Posted on 2018-08-21

941 A variably imprinted epiallele impacts seed development

Pignatta, D.; Novitzky, K.; Satyaki, P. R. V.; Gehring, M.

10.1101/339036 — plant biology — Posted on 2018-08-21

942 Large-Scale Annotation of Histopathology Images from Social Media

Schaumberg, A. J.; Juarez, W.; Choudhury, S. J.; Pastrian, L. G.; Pritt, B. S.; Prieto Pozuelo, M.; Sotillo Sanchez, R.; Ho, K.; Zahra, N.; Sener, B. D.; Yip, S.; Xu, B.; Annavarapu, S. R.; Morini, A.; Jones, K. A.; Rosado-Orozco, K.; Sirintrapun, S. J.; Aly, M.; Fuchs, T. J.

10.1101/396663 — pathology — Posted on 2018-08-21

943 Omitted variable bias in GLMs of neural spiking activity

Stevenson, I. H.

10.1101/317511 — neuroscience — Posted on 2018-08-21

944 Utility of the SWAN Scale for ADHD Trait-Based Genetic Research: A Validity and Polygenic Risk Study

Burton, C. L.; Wright, L.; Shan, J.; Xiao, B.; Dupuis, A.; Goodale, T.; Shaheen, S.-M.; Corfield, E. C.; Arnold, P. D.; Schachar, R. J.; Crosbie, J.

10.1101/248484 — genetics — Posted on 2018-08-21

945 The evolution of CHC22 clathrin influences its role in human glucose metabolism

Fumagalli, M.; Diekmann, Y.; Camus, S. M.; Burke, A.; Camus, M. D.; Norman, P. J.; Joseph, A.-P.; Abi-Rached, L.; Benazzo, A.; Rasteiro, R.; Mathieson, I.; Topf, M.; Parham, P.; Thomas, M. G.; Brodsky, F. M.

10.1101/307264 — genetics — Posted on 2018-08-21

946 Darwinian selection of host and bacteria supports emergence of Lamarckian-like adaptation of the system as a whole

Osmanovic, D.; Kessler, D. A.; Rabin, Y.; Soen, Y.

10.1101/093120 — evolutionary biology — Posted on 2018-08-21

947 Competition in biofilms between cystic fibrosis isolates of Pseudomonas aeruginosa is driven by R-pyocins

Oluyombo, O.; Diggle, S. P.; Penfold, C. N.

10.1101/264580 — microbiology — Posted on 2018-08-21

948 Cyfip1 haploinsufficiency increases compulsive-like behavior and modulates palatable food intake: Implications for Prader-Willi Syndrome

Babbs, R. K.; Ruan, Q. T.; Kelliher, J. C.; Beierle, J. A.; Chen, M. M.; Feng, A. X.; Kirkpatrick, S. L.; Benitez, F. A.; Rodriguez, F. A.; Pierre, J.; Anandakumar, J.; Kumar, V.; Mulligan, M. K.; Bryant, C. D.

10.1101/264846 — genetics — Posted on 2018-08-21

949 Transcriptomic Dynamics of a non-coding trinucleotide repeat expansion disorder SCA12 in iPSC derived neuronal cells: signatures of interferon induced response

Kumar, D.; Dhapola, P.; Hussain, A.; Kutum, R.; Srivastava, A. K.; Mukerji, M.; Mukherjee, O.; Faruq, M.

10.1101/201137 — molecular biology — Posted on 2018-08-21

950 90-90-90, epidemic control, and ending AIDS: review of global situation and recommendations

Granich, R.; Williams, B. G.; Gupta, S.; Zuniga, J. M.

10.1101/196972 — epidemiology — Posted on 2018-08-21

951 Competition for synaptic building blocks shapes synaptic plasticity

Triesch, J.; Vo, A. D.; Hafner, A.-S.

10.1101/166819 — neuroscience — Posted on 2018-08-21

952 Gut bacterial tyrosine decarboxylases restrict the bioavailability of levodopa, the primary treatment in Parkinson’s disease

van Kessel, S. P.; Frye, A. K.; El-Gendy, A. O.; Castejon, M.; Keshavarzian, A.; van Dijk, G.; El Aidy, S.

10.1101/356246 — molecular biology — Posted on 2018-08-21

953 Recurrent PD-L1 Structural Rearrangements in Natural Killer/T Cell Lymphoma Patients with Complete Response to PD-1 Blockade Therapy

Lim, J. Q.; Tang, T.; Cai, Q.-q.; Tan, D.; Nairismagi, M.-L.; Laurensia, Y.; Chia, B. K. H.; Peng, R.-J.; Iqbal, J.; Huang, D.; Song, T.; Pang, W. L.; Cheah, D. M. Z.; Ng, C. C. Y.; Rajasegaran, V.; Hong, H.; Tse, E.; Mow, B.; Cai, Q.-C.; Poon, L.-M.; Tan, J.; Grigoropoulos, N. F.; Goh, Y. T.; Phipps, C.; Rotzschke, O.; Cheng, C. L.; Lee, Y. S.; Loh, Y.; Tao, M.; Farid, M.; Au-Yeung, R.; Chan, T. S.-Y.; Ng, S.-B.; Kwong, Y.-L.; Hwang, W.; Chng, W.-J.; Tousseyn, T.; Tan, P.; Teh, B. T.; Khor, C. C.; Rozen, S.; Bei, J.-X.; Lin, T.; Lim, S. T.; Ong, C. K.

10.1101/372383 — genomics — Posted on 2018-08-21

954 Common genomic regions underlie natural variation in diverse toxin responses

Brady, S.; Evans, K.; Bloom, J.; Tanny, R.; Cook, D.; Giuliani, S.; Hippleheuser, S.; Zamanian, M.; Andersen, E.

10.1101/325399 — genetics — Posted on 2018-08-21

955 CryoEM structures of open dimers of Gyrase A in complex with DNA illuminate mechanism of strand passage

Soczek, K. M.; Grant, T.; Rosenthal, P. B.; Mondragon, A.

10.1101/397000 — biophysics — Posted on 2018-08-21

956 Genome Functional Annotation using Deep Convolutional Neural Networks

Khodabandelou, G.; Routhier, E.; Mozziconacci, J.

10.1101/330308 — bioinformatics — Posted on 2018-08-21

957 Positive human health effects of sea spray aerosols: molecular evidence from exposed lung cell lines.

Asselman, J.; Van Acker, E.; De Rijcke, M.; Tilleman, L.; Van Nieuwerburgh, F.; Mees, J.; De Schamphelaere, K.; Janssen, C.

10.1101/397141 — pharmacology and toxicology — Posted on 2018-08-21

958 Internal noise in contrast discrimination propagates forwards from early visual cortex

Vilidaite, G.; Marsh, E.; Baker, D.

10.1101/364612 — neuroscience — Posted on 2018-08-21

959 A large-scale systemic RNAi screen in the red flour beetle Tribolium castaneum identifies novel genes involved in arthropod muscle development

Schultheis, D.; Weisskopf, M.; Schaub, C.; Ansari, S.; Dao, V.-A.; Grossmann, D.; Majumdar, U.; Din Muhammad, M. S.; Troelenberg, N.; Richter, T.; Schmitt-Engel, C.; Schwirz, J.; Ströhlein, N.; Teuscher, M.; Bucher, G.; Frasch, M.

10.1101/397117 — developmental biology — Posted on 2018-08-21

960 JAK2 is highly expressed by cyst-lining cells and regulates cystogenesis.

Patera, F.; Cudzuch-Mardy, A.; Huang, Z.; Fragiadaki, M.

10.1101/378919 — cell biology — Posted on 2018-08-21

961 All four double-stranded RNA binding domains of Staufen2 contribute to efficient mRNA recognition and transcript localization

Heber, S.; Gaspar, I.; Tants, J.-N.; Günther, J.; Fernandez Moya, S. M.; Janowski, R.; Ephrussi, A.; Sattler, M.; Niessing, D.

10.1101/396994 — biochemistry — Posted on 2018-08-21

962 Somatically Mutated Genes Under Positive and Negative Selection Found by Transcriptome Sequence Analysis Include Oncogene and Tumor Suppressor Candidates

Drubin, C. W.; Ramu, A.; Rockweiler, N. B.; Conrad, D. F.

10.1101/396739 — genomics — Posted on 2018-08-21

963 The fitness consequences of genetic variation in wild populations of mice

Barrett, R. D. H.; Laurent, S.; Mallarino, R.; Pfeifer, S. P.; Xu, C. C. Y.; Foll, M.; Wakamatsu, K.; Duke-Cohan, J. S.; Jensen, J. D.; Hoekstra, H. E.

10.1101/383240 — evolutionary biology — Posted on 2018-08-21

964 Centrosome Aurora A gradient ensures a single PAR-2 polarity axis by regulating RhoGEF ECT-2 localization in C. elegans embryos

Kotak, S.; Kapoor, S.

10.1101/396721 — cell biology — Posted on 2018-08-21

965 Genome-wide patterns of gene expression in a wild primate indicate species-specific mechanisms associated with tolerance to natural simian immunodeficiency virus infection

Simons, N.; Eick, G. N.; Ruiz-Lopez, M. J.; Hyeroba, D.; Omeja, P. A.; Weny, G.; Chapman, C. A.; Goldberg, T. L.; Zheng, H.; Shankar, A.; Switzer, W. M.; Frost, S. D. W.; Jones, J. H.; Sterner, K. N.; Ting, N.

10.1101/395152 — genomics — Posted on 2018-08-21

966 Human Subthalamic Nucleus Selectively Decreases its Response to the Go-Signal in a Motor Inhibition Context

Marmor, O.; Rapple, P.; Valsky, D.; Bick, A.; Arkadir, D.; Linetzky, E.; Peled, O.; Tamir, I.; Bergman, H.; Israel, Z.; Eitan, R.

10.1101/392936 — neuroscience — Posted on 2018-08-21

967 Circadian control of lung inflammation in influenza infection

Sengupta, S.; Tang, S. Y.; Devine, J.; Nayak, S.; Zhang, S.; Valenzuela, A.; Lopez, C. B.; Grant, G.; FitzGerald, G. A.

10.1101/396556 — immunology — Posted on 2018-08-21

968 Macroevolutionary diversification rates show time-dependency

Henao Diaz, L. F.; Harmon, L. J.; Sugawara, M. T. C.; Pennell, M. W.

10.1101/396598 — evolutionary biology — Posted on 2018-08-21

969 Prescription Opioid Analgesic Use and Mortality in Systemic Lupus Erythematosus

Cabacungan, R. J.; Qualls, C. R.; Sibbitt, W. L.; Hayward, W. A.; Gibb, J. I.; Kettwich, S. D.; Fields, R. A.; Emil, N. S.; Fangtham, M.; Bankhurst, A. D.

10.1101/395343 — epidemiology — Posted on 2018-08-21

970 Glenohumeral Injection Using Anatomic Landmark Versus Sonographic Needle Guidance

Moore, T. S.; Paffett, C. F.; Sibbitt, W. L.; Hayward, W. A.; Gibb, J. I.; Kettwich, S. D.; Fields, R. A.; Emil, N. S.; Fangtham, M.; Bankhurst, A. D.

10.1101/395293 — clinical trials — Posted on 2018-08-21

971 Persistent hotspots of Schistosoma mansoni transmission in the Kenyan waters of Lake Victoria: a search for snail-related answers beneath the waves

Mutuku, M.; Laidemitt, M.; Mwangi, I.; Otiato, F.; Agola, E.; Steinauer, M.; Ochanda, H.; Kamel, B.; Loker, E.; Mkoji, G.

10.1101/394031 — epidemiology — Posted on 2018-08-21

972 Selecting causal risk factors from high-throughput experiments using multivariable Mendelian randomization

Zuber, V.; Colijn, J. M.; Klaver, C.; Burgess, S.

10.1101/396333 — genetics — Posted on 2018-08-21

973 Probabilistic modeling of personalized drug combinations from integrated chemical screen and molecular data in sarcoma

Berlow, N. E.; Rikhi, R.; Geltzeiler, M. N.; Abraham, J.; Svalina, M. N.; Davis, L. E.; Wise, E.; Mancini, M.; Noujaim, J.; Mansoor, A.; Quist, M. J.; Matlock, K. L.; Goros, M. W.; Hernandez, B. S.; Duong, Y. C.; Thway, K.; Tsukahara, T.; Nishio, J.; Huang, E. C.; Airhart, S.; Bult, C. J.; Gandour-Edwards, R.; Maki, R. G.; Jones, R. L.; Michalek, J. E.; Milovancev, M.; Ghosh, S.; Pal, R.; Keller, C.

10.1101/396358 — bioinformatics — Posted on 2018-08-21

974 Enhanced resistance to bacterial and oomycete pathogens by short tandem target mimic RNAs in tomato

Canto-Pastor, A.; Santos, B.; Valli, A.; Summers, W.; Schornack, S.; Baulcombe, D.

10.1101/396564 — plant biology — Posted on 2018-08-21

975 Function of the Pedicellate Spikelet and Awn in Sorghum and Related Grasses

AuBuchon-Elder, T.; Coneva, V.; Goad, D. M.; Allen, D. K.; Kellogg., E. A.

10.1101/396473 — plant biology — Posted on 2018-08-21

976 Dynamic regulation of HYL1 provides new insights into its multifaceted role in Arabidopsis

Bhagat, P. K.; Verma, D.; Badmi, R.; Sinha, A. K.

10.1101/396861 — plant biology — Posted on 2018-08-21

977 Single cell dynamics of embryonic muscle progenitor cells in zebrafish

Sharma, P.; Ruel, T. D.; Kocha, K. M.; Liao, S.; Huang, P.

10.1101/396713 — developmental biology — Posted on 2018-08-21

978 A neuromechanistic model for rhythmic beat generation

Bose, A.; Byrne, A.; Rinzel, J.

10.1101/397075 — neuroscience — Posted on 2018-08-21

979 In silico REPOSITIONING OF APPROVED DRUGS AGAINST Schistosoma mansoni ENERGY METABOLISM TARGETS

SILVA, L. D. A.; Bezerra, C. B.; dos Santos, D. B.; Calixto, N. M.

10.1101/397059 — bioinformatics — Posted on 2018-08-21

980 Cleaner wrasse pass the mark test. What are the implications for consciousness and self-awareness testing in animals?

Kohda, M.; Takashi, H.; Takeyama, T.; Awata, S.; Tanaka, H.; Asai, J.-y.; Jordan, A.

10.1101/397067 — animal behavior and cognition — Posted on 2018-08-21

981 Metagenomic analysis with strain-level resolution reveals fine-scale variation in the human pregnancy microbiome

Goltsman, D. S. A.; Sun, C. L.; Proctor, D. M.; DiGiulio, D. B.; Robaczewska, A.; Thomas, B. C.; Shaw, G. M.; Stevenson, D. K.; Holmes, S. P.; Banfield, J. F.; Relman, D. A.

10.1101/266700 — microbiology — Posted on 2018-08-21

982 Bidirectional intraflagellar transport is restricted to two sets of microtubule doublets in the trypanosome flagellum

Bertiaux, E.; Mallet, A.; Fort, C.; Blisnick, T.; Bonnefoy, S.; Jung, J.; Lemos, M.; Marco, S.; Vaughan, S.; Trepout, S.; Tinevez, J.-Y.; Bastin, P.

10.1101/329300 — cell biology — Posted on 2018-08-21

983 Synaptic integration across first-order tactile neurons can discriminate edge orientations with high acuity and speed

Hay, E.; Pruszynski, J. A.

10.1101/396705 — neuroscience — Posted on 2018-08-20

984 40 Hz acoustic stimulation decreases amyloid beta and modulates brain rhythms in a mouse model of Alzheimers disease

Lee, J.; Ryu, S.; Kim, H.; Jung, J.; Lee, B.; Kim, T.

10.1101/390302 — neuroscience — Posted on 2018-08-20

985 Deciphering the Dynamics of Interlocked Feedback Loops in a Model of the Mammalian Circadian Clock

Battogtokh, D.; Tyson, J. J.

10.1101/306852 — systems biology — Posted on 2018-08-20

986 PARylation modulates stress granule assembly, phase separation, and neurotoxicity of disease-related RNA-binding proteins

Duan, Y.; Du, A.; Gu, J.; Duan, G.; Wang, C.; Sun, L.; Qian, B.; Deng, X.; Zhang, K.; Tian, K.; Zhang, Y.; Jiang, H.; Liu, C.; Fang, Y.

10.1101/396465 — neuroscience — Posted on 2018-08-20

987 Deterministic splicing of Dscam2 is regulated by Muscleblind

Li, J. S. S.; Millard, S. S.

10.1101/297101 — neuroscience — Posted on 2018-08-20

988 High Postoperative Monocyte Predicts Worse Lung Adenocarcinoma or Squamous Cell Carcinoma Outcomes

Hai, Y.; Chen, N.; Wu, W.; Wang, Z.; Lin, F.; Guo, C.; Liu, C.; Li, W.; Liu, L.

10.1101/395632 — cancer biology — Posted on 2018-08-20

989 Zebrafish Otolith Biomineralization Requires Polyketide Synthase

Thiessen, K. D.; Higuchi, L.; Kramer, K. L.

10.1101/396630 — developmental biology — Posted on 2018-08-20

990 DEVELOPMENTAL DYNAMICS OF GREEN FLUORESCENT CHROMATOPHORES IN THE DAGGERBLADE GRASS SHRIMP, PALAEMONETES PUGIO HOLTHUIS, 1949 (DECAPODA, CARIDEA, PALAEMONIDAE)

Phelps, M. P.

10.1101/396648 — developmental biology — Posted on 2018-08-20

991 Genotype-by-environment-by-environment interactions in the Saccharomyces cerevisiae transcriptomic response to alcohols and anaerobiosis

Gasch, A. P.; Sardi, M.; Krause, M.; Heilberger, J.

10.1101/396531 — genomics — Posted on 2018-08-20

992 Mortality causes universal changes in microbial community composition

Abreu, C. I.; Friedman, J.; Andersen Woltz, V. L.; Gore, J.

10.1101/396499 — ecology — Posted on 2018-08-20

993 Force localization modes in dynamic epithelial colonies

Schaumann, E. N.; Staddon, M. F.; Gardel, M. L.; Banerjee, S.

10.1101/336164 — biophysics — Posted on 2018-08-20

994 Nanopore sequence-based genome assembly of the basmati rice

Choi, J. Y.; Groen, S.; Zaaijer, S.; Purugganan, M.

10.1101/396515 — evolutionary biology — Posted on 2018-08-20

995 Promoting synthetic symbiosis under environmental disturbances

Denton, J.; Gokhale, C. S.

10.1101/395426 — evolutionary biology — Posted on 2018-08-20

996 Compression-Assisted Arthrocentesis of the Knee as a Quality Improvement Intervention

Bennett, J. F.; Sibbitt, W. L.; Band, P. A.; Yaqub, S.; Emil, N. S.; Fangtham, M.; Fields, R. A.; Hayward, W. A.; Kettwich, S. D.; Bankhurst, A. D.

10.1101/395376 — bioengineering — Posted on 2018-08-20

997 Computations performed by shadow enhancers and enhancer duplications vary across the Drosophila embryo

Scholes, C.; Biette, K. M.; Harden, T. T.; DePace, A. H.

10.1101/396457 — systems biology — Posted on 2018-08-20

998 cAMP stimulates SLC26A3 activity in human colon by a CFTR-dependent mechanism that does not require CFTR activity

Tse, C.-M.; Yin, J.; Singh, V.; Sarker, R.; Lin, R.; Verkman, A. S.; Turner, J. R.; Donowitz, M.

10.1101/396408 — physiology — Posted on 2018-08-20

999 New inhibitors of Mycobacterium tuberculosis identified using systems chemical biology

Johnson, E. O.; LaVerriere, E.; Stanley, M.; Office, E.; Meyer, E.; Kawate, T.; Gomez, J.; Audette, R. E.; Bandyopadhyay, N.; Betancourt, N.; Delano, K.; Da Silva, I.; Davis, J.; Gallo, C.; Gardner, M.; Golas, A.; Guinn, K. M.; Korn, R.; McConnell, J. A.; Moss, C. E.; Murphy, K. C.; Nietupski, R.; Papavinasasundaram, K. G.; Pinkham, J. T.; Pino, P. A.; Proulx, M. K.; Ruecker, N.; Song, N.; Thompson, M.; Trujillo, C.; Wakabayashi, S.; Wallach, J. B.; Watson, C.; Ioerger, T. R.; Lander, E. S.; Hubbard, B. K.; Serrano-Wu, M. H.; Ehrt, S.; Fitzgerald, M.; Rubin, E. J.; Sassetti, C. M.; Schnappinge

10.1101/396440 — microbiology — Posted on 2018-08-20

1000 Photon count estimation in single-molecule localization microscopy

Rieger, B.; Stallinga, S.; Hulleman, C. N.; Thorsen, R. O.; Grunwald, D.; Hammer, M.

10.1101/396424 — molecular biology — Posted on 2018-08-20

1001 Testing Causal Bidirectional Influences between Physical Activity and Depression using Mendelian Randomization

Choi, K. W.; Chen, C.-Y.; Stein, M. B.; Klimentidis, Y. C.; Wang, M.-J.; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, ; Koenen, K. C.; Smoller, J. W.

10.1101/364232 — genetics — Posted on 2018-08-20

1002 Biophysically Realistic Neuron Models for Simulation of Cortical Stimulation

Aberra, A. S.; Peterchev, A. V.; Grill, W. M.

10.1101/328534 — bioengineering — Posted on 2018-08-20

1003 PARylation modulates stress granule assembly, phase separation, and neurotoxicity of ALS-related RNA-binding proteins

Duan, Y.; Du, A.; Gu, J.; Duan, G.; Wang, C.; Sun, L.; Qian, B.; Deng, X.; Zhang, K.; Tian, K.; Jiang, H.; Zhang, Y.; Liu, C.; Fang, Y.

10.1101/396465 — neuroscience — Posted on 2018-08-20

1004 New human chromosomal safe harbor sites for genome engineering with CRISPR/Cas9, TAL effector and homing endonucleases

Pellenz, S.; Phelps, M. P.; Tang, W.; Hovde, B. T.; Sinit, R.; Fu, W.; Li, H.; Chen, E.; Monnat, R.

10.1101/396390 — genomics — Posted on 2018-08-20

1005 Automated Electrodes Detection during simultaneous EEG/fMRI

Fleury, M.; Barillot, C.; Mano, M.; Bannier, E.; Maurel, P.

10.1101/395806 — neuroscience — Posted on 2018-08-20

1006 Deep learning: Using machine learning to study biological vision

Majaj, N. J.; Pelli, D. G.

10.1101/178152 — neuroscience — Posted on 2018-08-20

1007 GBAT: a gene-based association method for robust trans-gene regulation detection

Liu, X.; Mefford, J. A.; Dahl, A.; Subramaniam, M.; Battle, A.; Price, A. L.; Zaitlen, N.

10.1101/395970 — genetics — Posted on 2018-08-20

1008 Evolutionary history of Alzheimer Disease causing protein family Presenilins with pathological implications.

Khan, A. A.; Parveen, B.; Raja, H. A.

10.1101/394270 — evolutionary biology — Posted on 2018-08-20

1009 Choanoflagellate transfection illuminates their cell biology and the ancestry of animal septins

Booth, D.; Middleton, H.; King, N.

10.1101/343111 — cell biology — Posted on 2018-08-20

1010 Modeling the MYC-driven normal-to-tumour switch in breast cancer.

Lourenco, C.; Kalkat, M.; Houlahan, K. E.; De Melo, J.; Longo, J.; Done, S. J.; Boutros, P. C.; Penn, L. Z.

10.1101/380931 — cancer biology — Posted on 2018-08-20

1011 Conformational ensemble of the human TRPV3 ion channel

Zubcevic, L.; Herzik, M. A.; Wu, M.; Borschel, W. F.; Hirschi, M.; Song, A.; Lander, G. C.; Lee, S.-Y.

10.1101/395616 — biochemistry — Posted on 2018-08-20

1012 Regularization Improves the Robustness of Learned Sequence-to-Expression Models

Lunt, B. J.; Sinha, S.

10.1101/393835 — systems biology — Posted on 2018-08-20

1013 The sunlit microoxic niche of the archaeal eukaryotic ancestor comes to light

Bulzu, P.-A.; Andrei, A.-S.; Salcher, M. M.; Mehrshad, M.; Inoue, K.; Kandori, H.; Beja, O.; Ghai, R.; Banciu, H.

10.1101/385732 — microbiology — Posted on 2018-08-20

1014 Endogenous viral elements are widespread in arthropod genomes and commonly give rise to piRNAs

ter Horst, A. M.; Nigg, J. C.; Falk, B. W.

10.1101/396382 — microbiology — Posted on 2018-08-20

1015 Computational performance and accuracy of Sentieon DNASeq variant calling workflow

Kendig, K.; Baheti, S.; Bockol, M. A.; Drucker, T. M.; Hart, S. N.; Heldenbrand, J. R.; Hernaez, M.; Hudson, M. E.; Kalmbach, M. T.; Klee, E. W.; Mattson, N. R.; Ross, C. A.; Taschuk, M.; Wieben, E. D.; Wiepert, M.; Wildman, D. E.; Mainzer, L. S.

10.1101/396325 — bioinformatics — Posted on 2018-08-20

1016 Allele-specific binding of RNA-binding proteins reveals functional genetic variants in the RNA

Yang, E.-W.; Bahn, J. H.; Hsiao, E. Y.-H.; Tan, B. X.; Sun, Y.; Fu, T.; Zhou, B.; Van Nostrand, E. L.; Pratt, G. A.; Freese, P.; Wei, X.; Quinones-Valdez, G.; Urban, A. E.; Graveley, B. R.; Burge, C. B.; Yeo, G. W.; Xiao, X.

10.1101/396275 — bioinformatics — Posted on 2018-08-20

1017 Comparative Multi-scale Hierarchical Structure of the Tail, Plantaris, and Achilles Tendons in the Rat

Lee, A. H.; Elliott, D. M.

10.1101/396309 — bioengineering — Posted on 2018-08-20

1018 On the Number of Driver Nodes for Controlling a Boolean Network to Attractors

Hou, W.; Ruan, P.; Ching, W.-K.; Akutsu, T.

10.1101/395442 — systems biology — Posted on 2018-08-20

1019 Oscillatory brain states govern spontaneous fMRI network dynamics

Gutierrez-Barragan, D.; Basson, M. A.; Panzeri, S.; Gozzi, A.

10.1101/393389 — neuroscience — Posted on 2018-08-20

1020 A Data Structure for real-time Aggregation Queries of Big Brain Networks

Ganglberger, F.; Kaczanowska, J.; Haubensak, W.; Buehler, K.

10.1101/346338 — neuroscience — Posted on 2018-08-20

1021 A 7-member SNP Assay on the iPlex MassARRAY Platform Provides a Rapid and Affordable Alternative to Typing Major African Staphylococcus aureus Types

Musila, L. A.; Nyasinga, J. T.; Kyany'a, C.; Okoth, R.; Oundo, V.; Matano, D.; Wacira, S.; Sang, W.; Musembi, S.

10.1101/395079 — microbiology — Posted on 2018-08-20

1022 Experimental and mathematical approaches to quantify recirculation kinetics of lymphocytes

Ganusov, V. V.; Tomura, M.

10.1101/268326 — immunology — Posted on 2018-08-20

1023 Independent component analysis provides clinically relevant insights into the biology of melanoma patients

Nazarov, P. V.; Wienecke-Baldacchino, A. K.; Zinovyev, A.; Czerwinska, U.; Muller, A.; Nashan, D.; Dittmar, G.; Azuaje, F.; Kreis, S.

10.1101/395145 — genomics — Posted on 2018-08-20

1024 CRUMBLER: A tool for the Prediction of Ancestry in Cattle

Crum, T. E.; Schnabel, R. D.; Decker, J. E.; Regitano, L. C.; Taylor, J. F.

10.1101/396341 — genomics — Posted on 2018-08-20

1025 Fast Estimation of Recombination Rates Using Topological Data Analysis

Humphreys, D. P.; McGuirl, M. R.; Miyagi, M.; Blumberg, A. J.

10.1101/395210 — evolutionary biology — Posted on 2018-08-20

1026 The RNA helicase UPF1 associates with mRNAs co-transcriptionally and is required in nuclear processes of gene expression

Singh, A. K.; Choudhury, S. R.; De, S.; Zhang, J.; Kissane, S.; Dwivedi, V.; Ramanathan, P.; Orsini, L.; Hebenstreit, D.; Brogna, S.

10.1101/395863 — cell biology — Posted on 2018-08-20

1027 Multiple-gene targeting and mismatch tolerance can confound analysis of genome-wide pooled CRISPR screens

Fortin, J.-P.; Gascoigne, K. E.; Haverty, P. M.; Forrest, W. F.; Costa, M. R.; Martin, S. E.

10.1101/387258 — bioinformatics — Posted on 2018-08-20

1028 SureTypeSC - A Random Forest and Gaussian Mixture predictor of high confidence genotypes in single cell data

Vogel, I.; Blanshard, R. C.; Hoffmann, E. R.

10.1101/393256 — bioinformatics — Posted on 2018-08-20

1029 Cell Diameter in Bacillus subtilis is Determined by the Opposing Actions of Two Distinct Cell Wall Synthetic Systems

Dion, M.; Kapoor, M.; Sun, Y.; Wilson, S.; Ryan, J.; Vigouroux, A.; van Teeffelen, S.; Oldenbourg, R.; Garner, E. C.

10.1101/392837 — microbiology — Posted on 2018-08-20

1030 Human antibody cocktail deploys multiple functions to confer pan-ebolavirus protection

Wec, A. Z.; Bornholdt, Z. A.; He, S.; Herbert, A. S.; Goodwin, E.; Wirchnianski, A. S.; Gunn, B. M.; Zhang, Z.; Zhu, W.; Liu, G.; Abelson, D. M.; Moyer, C. L.; Jangra, R. K.; James, R. M.; Bakken, R. R.; Bohorova, N.; Bohorov, O.; Kim, D. H.; Pauly, M. H.; Velasco, J.; Bortz, R. H.; Whaley, K. J.; Goldstein, T.; Anthony, S. J.; Alter, G.; Walker, L. M.; Dye, J. M.; Zeitlin, L.; Qiu, X.; Chandran, K.

10.1101/395525 — microbiology — Posted on 2018-08-20

1031 Spatial Structure Can Decrease Symbiotic Cooperation

Vostinar, A. E.; Ofria, C.

10.1101/393868 — evolutionary biology — Posted on 2018-08-20

1032 High Postoperative Monocyte Predicts Worse Lung Adenocarcinoma or Squamous Cell Carcinoma Outcomes

Hai, Y.; Chen, N.; Zhou, J.

10.1101/395632 — cancer biology — Posted on 2018-08-20

1033 Proprioceptive Sonomyographic Control: A novel method of intuitive proportional control of multiple degrees of freedom for upper-extremity amputees

Dhawan, A. S.; Mukherjee, B.; Patwardhan, S.; Akhlaghi, N.; Levay, G.; Holley, R. J.; Joiner, W. M.; Harris-Love, M.; Sikdar, S.

10.1101/387290 — bioengineering — Posted on 2018-08-20

1034 p38α in CD11c+ cells drives sex-specific differences during progression of autoimmune demyelination

Chechneva, O.; Mayrhofer, F.; Dariychuk, Z.; Zhen, A.; Pleasure, D. E.; Deng, W.

10.1101/396036 — neuroscience — Posted on 2018-08-20

1035 Inhibition of HtrA2 alleviated colitis by preventing necroptosis of intestinal epithelial cells

Yan, J.; Zhang, C.; He, A.; Liu, S.; He, Q.; Luo, Y.; Chen, Y.; He, Z.; Tao, A.

10.1101/395897 — molecular biology — Posted on 2018-08-20

1036 Characterization of L-serine deaminases, SdaA (PA2448) and SdaB (PA5379), and their potential role in Pseudomonas aeruginosa pathogenesis

Mathee, K.; Leal, S. M.; Newman, E.

10.1101/394957 — microbiology — Posted on 2018-08-20

1037 CryoEM structures of MDA5-dsRNA filaments at different stages of ATP hydrolysis

Yu, Q.; Qu, K.; Modis, Y.

10.1101/376319 — immunology — Posted on 2018-08-20

1038 Cooperativity and Avidity in Membrane Binding by C2AB Tandem Domains of Synaptotagmins 1 and 7

Tran, H. T.; Anderson, L. H.; Knight, J. D.

10.1101/393702 — biophysics — Posted on 2018-08-20

1039 Occurrence of non-western magic in the European brain

Koten, J. W.; Schueppen, A.; Kumar, V.; Wood, G.

10.1101/395285 — neuroscience — Posted on 2018-08-20

1040 ML-DSP: Machine Learning with Digital Signal Processing for ultrafast, accurate, and scalable genome classification at all taxonomic levels

Randhawa, G. S.; Hill, K. A.; Kari, L.

10.1101/394932 — genomics — Posted on 2018-08-20

1041 Interacting effects of the abiotic and biotic environment on fitness of rainforest Drosophila

O'Brien, E. K.; Higgie, M.; Jeffs, C. T.; Hoffmann, A. A.; Hrcek, J.; Lewis, O. T.; Bridle, J. R.

10.1101/395624 — evolutionary biology — Posted on 2018-08-20

1042 Herd protection against Plasmodium falciparum infections conferred by mass antimalarial drug administrations and the implications for malaria elimination

Parker, D. M.; Tun, S. T. T.; White, L.; Kajeechiwa, L.; Thwin, M. M.; Landier, J.; Chaumeau, V.; Corbel, V.; Dondorp, A. M.; von Seidlein, L.; White, N. J.; Maude, R. J.; Nosten, F. H.

10.1101/393843 — epidemiology — Posted on 2018-08-20

1043 The nature and intensity of mechanical stimulation drive different dynamics of MRTF-A nuclear redistribution after actin remodeling in myoblasts

Montel, L.; Sotiropoulos, A.; Henon, S.

10.1101/395962 — biophysics — Posted on 2018-08-20

1044 Unstable Angina is a syndrome correlated to Th17 inflammatory disorder

Hu, W.

10.1101/396267 — bioinformatics — Posted on 2018-08-20

1045 Network analysis of lymphocyte nucleus staining image

Li, D.-D.; Yang, X.-L.; Xiong, Q.-Y.; Liang, Y.-D.; Liu, S.-Q.; Hu, H.-Y.; Zhou, X.-h.; Huang, H.

10.1101/396143 — bioinformatics — Posted on 2018-08-20

1046 Compression-Assisted Arthrocentesis of the Knee as a Quality Improvement Intervention

Bennett, J. F.; Sibbitt, W. L.; Band, P. A.; Yqub, S.; Emil, N. S.; Fangtham, M.; Fields, R. A.; Hayward, W. A.; Kettwich, S. D.; Bankhurst, A. D.

10.1101/395376 — bioengineering — Posted on 2018-08-20

1047 The freeze-dried extracts of Salvia coccinea Juss. Ex Murray attenuate myocardial ischemia reperfusion injury in a global ischemia Rat model

NYAGA, N. M.; MWANGI, P. W.; Bukachi, F.

10.1101/396119 — physiology — Posted on 2018-08-20

1048 Mitogen activated protein kinases function as a cohort during a plant defense response

McNeece, B. T.; Sharma, K.; Lawrence, G. W.; Lawrence, K. S.; Klink, V. P.

10.1101/396192 — molecular biology — Posted on 2018-08-20

1049 Butyrivibrio hungatei MB2003 competes effectively for soluble sugars released by Butyrivibrio proteoclasticus B316T from growth on xylan or pectin

Palevich, N.; Kelly, W. J.; Ganesh, S.; Rakonjac, J.; Attwood, G. T.

10.1101/395103 — microbiology — Posted on 2018-08-20

1050 Evolutionary history of Alzheimer Disease causing protein family Presenilins with pathological implications.

Khan, A.; Parveen, B.; Raja, H. A.

10.1101/394270 — evolutionary biology — Posted on 2018-08-20

1051 Viruses.STRING: A virus-host protein-protein interaction database

Cook, H. V. V.; Doncheva, N.; Szklarczyk, D.; von Mering, C.; Jensen, L. J.

10.1101/396184 — bioinformatics — Posted on 2018-08-20

1052 Identity domains in complex behavior: Toward a biology of personality

Forkosh, O.; Karamihalev, S.; Roeh, S.; Engel, M.; Alon, U.; Anpilov, S.; Nussbaumer, M.; Flachskamm, C.; Kaplick, P.; Shemesh, Y.; Chen, A.

10.1101/395111 — animal behavior and cognition — Posted on 2018-08-20

1053 A note on stochastic modeling of biological systems: automatic generation of an optimized Gillespie algorithm

Vanhaelen, Q.

10.1101/395392 — systems biology — Posted on 2018-08-20

1054 Neural Correlates of Causal Confounding

Liljeholm, M.

10.1101/395707 — neuroscience — Posted on 2018-08-20

1055 Performance evaluation of inverse methods for identification and characterization of oscillatory brain sources: Ground truth validation & empirical evidences

Halder, T.; Talwar, S.; Jaiswal, A.; Banerjee, A.

10.1101/395780 — neuroscience — Posted on 2018-08-20

1056 Bariatric surgery changes gut microbiota composition independent of operation type

10.1101/395657 — microbiology — Posted on 2018-08-20

1057 The comparative biogeography of geckos challenges predictions from a paradigm of climate-driven vicariant diversification across an island archipelago

Oaks, J. R.; Siler, C. D.; Brown, R. M.

10.1101/395434 — evolutionary biology — Posted on 2018-08-20

1058 A Single Adaptive Mutation in Sodium Taurocholate Cotransporting Polypeptide Induced by Hepadnaviruses Determines Virus Species-specificity

Takeuchi, J. S.; Fukano, K.; Iwamoto, M.; Tsukuda, S.; Suzuki, R.; Aizaki, H.; Muramatsu, M.; Wakita, T.; Sureau, C.; Watashi, K.

10.1101/391490 — evolutionary biology — Posted on 2018-08-20

1059 Life-history traits inform on population trends when assessing the conservation status of a declining tiger shark population

Brown, C.; Roff, G.

10.1101/395509 — ecology — Posted on 2018-08-20

1060 Xenopus hybrids provide insight into cell and organism size control

Gibeaux, R.; Miller, K.; Acker, R.; Kwon, T.; Heald, R.

10.1101/395814 — developmental biology — Posted on 2018-08-20

1061 Circular RNAs regulate cancer stem cells by FMRP against CCAR1 complex in hepatocellular carcinoma

Wang, H.-Y.; Zhu, Y.-J.; Zheng, B.; Ma, X.-K.; Lu, X.-Y.; Lin, X.-M.; Luo, G.-J.; Yang, S.; Zhao, Q.; Chen, X.; Yang, Y.-C.; Liu, X.-L.; Wu, R.; Liu, J.; Ge, Y.; Yang, L.; Chen, L.

10.1101/396069 — cancer biology — Posted on 2018-08-20

1062 The fungal root endophyte Serendipita indica modifies extracellular nucleotides to subvert plant immunity

Nizam, S.; Qiang, X.; Wawra, S.; Nostadt, R.; Getzke, F.; Schwanke, F.; Dreyer, I.; Langen, G.; Zuccaro, A.

10.1101/396028 — plant biology — Posted on 2018-08-20

1063 A systematic bias in DTI findings

Sepehrband, F.; Cabeen, R. P.; Choupan, J.; Barisano, G.; Law, M.; Toga, A. W.; the Alzheimers Disease Neuroimaging Initiative,

10.1101/395012 — neuroscience — Posted on 2018-08-20

1064 Transmission of motor signals from the basal ganglia to the thalamus: effect of correlations, sensory responses, and excitation

Mohagheghi Nejad, M.; Rotter, S.; Schmidt, R.

10.1101/386920 — neuroscience — Posted on 2018-08-20

1065 GBAT: a gene-based association method for robust trans-gene regulation detection

Liu, X.; Mefford, J. A.; Dahl, A.; Subramaniam, M.; Battle, A.; Price, A. L.; Zaitlen, N.

10.1101/395970 — genetics — Posted on 2018-08-20

1066 Efficient variant set mixed model association tests for continuous and binary traits in large-scale whole genome sequencing studies

Chen, H.; Huffman, J. E.; Brody, J. A.; Wang, C.; Lee, S.; Li, Z.; Gogarten, S. M.; Sofer, T.; Bielak, L. F.; Bis, J. C.; Blangero, J.; Bowler, R. P.; Cade, B. E.; Cho, M. H.; Correa, A.; Curran, J. E.; de Vries, P. S.; Glahn, D. C.; Guo, X.; Johnson, A. D.; Kardia, S.; Kooperberg, C.; Lewis, J. P.; Liu, X.; Mathias, R. A.; Mitchell, B. D.; O'Connell, J. R.; Peyser, P. A.; Post, W. S.; Reiner, A. P.; Rich, S. S.; Rotter, J. I.; Silverman, E. K.; Smith, J. A.; Vasan, R. S.; Wilson, J. G.; Yanek, L. R.; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, ; TOPMed Hematology and Hemos

10.1101/395046 — genetics — Posted on 2018-08-20

1067 The Evolution of Phenotypic Plasticity when Environments Fluctuate in Time and Space

King, J. G.; Hadfield, J. D.

10.1101/395137 — evolutionary biology — Posted on 2018-08-20

1068 Environmental disturbances compromise synthetic symbiosis

Denton, J.; Gokhale, C. S.

10.1101/395426 — evolutionary biology — Posted on 2018-08-20

1069 Identification of negative BOLD responses using windkessel models

Valdes-Hernandez, P. A.; Bernal, B.; Moshkforoush, A.; Dunoyer, C.; Ming Khoo, H.; Bosch-Bayard, J.; von Ellenrieder, N.; Gotman, J.; Riera, J. J.

10.1101/392290 — neuroscience — Posted on 2018-08-20

1070 Adaptation of artificial diets for Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae) at laboratory rearing

Truzi, C. C.; Chamessanga, J. A.; Holzhausen, H. G.; Laurentis, V. L.; Vieira, N. F.; Vacari, A.; De Bortoli, S. A.

10.1101/396242 — zoology — Posted on 2018-08-20

1071 p75 Neurotrophin Receptor Regulates the Timing of the Maturation of Cortical Parvalbumin Cell Connectivity and Promotes Ocular Dominance Plasticity in Adult Visual Cortex.

Baho, E.; Chattopadhyaya, B.; Lavertu-Jolin, M.; Mazziotti, R.; Awad, P. N.; Chehrazi, P. N.; Groleau, M.; Jahannault-Talignani, C.; Sanon, N. T.; Vaucher, E. T.; Ango, F.; Pizzorusso, T.; Baroncelli, L.; Di Cristo, G.

10.1101/392159 — neuroscience — Posted on 2018-08-20

1072 22kHz and 55kHz ultrasonic vocalizations differentially influence neural and behavioral outcomes: Implications for modeling anxiety via auditory stimuli in the rat

Demaestri, C.; Brenhouse, H. C.; Honeycutt, J. A.

10.1101/395772 — neuroscience — Posted on 2018-08-20

1073 Splice variants of DOMINO control Drosophila circadian behavior and pacemaker neuron maintenance

Liu, Z.; Niu, Y.; Lam, V. H.; Chiu, J. C.; Zhang, Y.

10.1101/395848 — neuroscience — Posted on 2018-08-20

1074 Human-specific ARHGAP11B induces hallmarks of neocortical expansion in developing ferret neocortex

Kalebic, N.; Gilardi, C.; Albert, M.; Namba, T.; Long, K. R.; Kostic, M.; Langen, B.; Huttner, W. B.

10.1101/395830 — neuroscience — Posted on 2018-08-20

1075 MafK mediates chromatin remodeling to silence IRF8 expression in non-immune cells in a lineage-specific manner

Fourier, N.; Zolty, M.; Azriel, A.; Tedesco, D.; Levi, B.-Z.

10.1101/396291 — molecular biology — Posted on 2018-08-20

1076 In Silico Identification and In Vitro Validation of Novel KPC-2 β-lactamase Inhibitors

Klein, R.; Linciano, P.; Celenza, G.; Bellio, P.; Papaioannou, S.; Blazquez, J.; Cendron, L.; Brenk, R.; Tondi, D.

10.1101/396283 — biochemistry — Posted on 2018-08-20

1077 Epigallocatechin-3-gallate yield in different temperature gradients in green tea (Camellia sinensis) brewing

Hsieh, M.-h.; Hsieh, M.-j.; Wu, C.-R.; Peng, W.-h.; Hsieh, M.-t.; Hsieh, C.-c.

10.1101/396234 — plant biology — Posted on 2018-08-20

1078 Excitable dynamics through toxin-induced mRNA cleavage in bacteria

Vet, S.; Vandervelde, A.; Gelens, L.

10.1101/396226 — systems biology — Posted on 2018-08-20

1079 Mindfulness meditators show altered distributions of early and late neural activity markers of attention in a response inhibition task

Bailey, N.; Freedman, G.; Raj, K.; Sullivan, C.; Rogasch, N.; Chung, S.; Hoy, K.; Chambers, R.; Hassed, C.; Van Dam, N.; Fitzgerald, P.

10.1101/396259 — neuroscience — Posted on 2018-08-20

1080 Regeneration-Associated Cells Improve Recovery from Myocardial Infarction through Enhanced Vasculogenesis, Anti-inflammation, and Cardiomyogenesis

Salybekov, A. A.; Kawaguchi, A. T.; Masuda, H.; Vorateera, K.; Okada, C.; Asahara, T.

10.1101/396101 — systems biology — Posted on 2018-08-20

1081 Implicit and explicit learning in reactive and voluntary saccade adaptation

van Es, D. M.; Knapen, T.

10.1101/396150 — neuroscience — Posted on 2018-08-20

1082 Identifying incident dementia by applying machine learning to a very large administrative claims dataset

Nori, V. S.; Hane, C. A.; Martin, D. C.; Sanghavi, D. M.; Kravetz, A. D.

10.1101/396127 — bioinformatics — Posted on 2018-08-20

1083 Decoupling between causal understanding and awareness during learning and inference

Lee, J.; Kralik, J. D.; Cha, Y.; Heo, S.; Lee, S. W.

10.1101/391938 — neuroscience — Posted on 2018-08-20

1084 SNP Variable Selection by Generalized Graph Domination

Sun, S.; Miao, Z.; Ratcliffe, B.; Campbell, P.; Pasch, B.; El-Kassaby, Y. A.; Balasundaram, B.; Chen, C.

10.1101/396085 — genetics — Posted on 2018-08-20

1085 Expression based biomarkers and models to classify early and late stage samples of Papillary Thyroid Carcinoma

Bhalla, S.; Kaur, H.; Kaur, R.; Sharma, S.; Raghava, G.

10.1101/393975 — bioinformatics — Posted on 2018-08-20

1086 Decomposing cell identity for transfer learning across cellular measurements, platforms, tissues, and species.

Stein-O'Brien, G. L.; Clark, B. S.; Sherman, T.; Zibetti, C.; Hu, Q.; Sealfon, R.; Liu, S.; Qian, J.; Colantuoni, C.; Blackshaw, S.; Goff, L. A.; Fertig, E. J.

10.1101/395004 — bioinformatics — Posted on 2018-08-20

1087 Dear Editor PLOS ONEThe freeze-dried extracts of Salvia coccinea Juss. Ex Murray attenuate myocardial ischemia reperfusion injury in a global ischemia Rat model

NYAGA, N. M.; MWANGI, P. W.; Bukachi, F.

10.1101/396119 — physiology — Posted on 2018-08-20

1088 Impact of fruit-tree shade intensity on the growth, yield, and quality of intercropped wheat

Qiao, X.; Sai, L.; Chen, X.; Xue, L.; Lei, J.

10.1101/396010 — physiology — Posted on 2018-08-20

1089 Importance of vitamin D in critically ill children with subgroup analyses of sepsis and respiratory tract infections: a systematic review and meta-analysis

Cariolou, M.; Cupp, M. A.; Evangelou, E.; Tzoulaki, I.; Berlanga-Taylor, A. J.

10.1101/390476 — epidemiology — Posted on 2018-08-20

1090 Determination of essential phenotypic elements of clusters in high-dimensional entities - DEPECHE

Theorell, A.; Bryceson, Y. T.; Theorell, J.

10.1101/396135 — bioinformatics — Posted on 2018-08-20

1091 Label free quantitative proteomics of Qualea grandiflora Mart. (Vochysiaceae) roots indicates an aluminium requirement for growth and development.

Cury, N. F.; Silva, R. C. C.; Melo, J. R.; Andre, M. S. F.; Fontes, W.; Ricart, C. A. O.; Castro, M. S.; Silveira, C. E. d. S.; Sousa, M. V. d.; Pereira, L. A. R.

10.1101/396093 — plant biology — Posted on 2018-08-20

1092 Cyclin B3 is specifically required for metaphase to anaphase transition in mouse oocyte meiosis I

Li, Y.; Wang, L.; Zhang, L.; He, Z.; Feng, G.; Sun, H.; Wang, J.; Li, Z.; Liu, C.; Han, J.; Mao, J.; Yuan, X.; Jiang, L.; Zhang, Y.; Zhou, Q.; Li, W.

10.1101/390351 — cell biology — Posted on 2018-08-20

1093 NHBA is processed by kallikrein from human saliva

Pantano, E.; Cartocci, E.; Marchi, S.; Biagini, M.; Di Fede, M.; Nardi Dei, V.; Rossi Paccani, S.; Pizza, M.

10.1101/395988 — biochemistry — Posted on 2018-08-20

1094 Maize YABBY drooping leaf genes regulate floret development and floral meristem determinacy

Strable, J.; Vollbrecht, E.

10.1101/395186 — plant biology — Posted on 2018-08-20

1095 An interaction network of the human SEPT9 established by quantitative mass spectrometry reveals an interplay with myosin motors

Hecht, M.; Rösler, R.; Wiese, S.; Johnsson, N.; Gronemeyer, T.

10.1101/395996 — cell biology — Posted on 2018-08-20

1096 Robust Automated Assessment of Human Blastocyst Quality using Deep Learning

Khosravi, P.; Kazemi, E.; Zhan, Q.; Toschi, M.; E. Malmsten, J.; Hickman, C.; Meseguer, M.; Rosenwaks, Z.; Elemento, O.; Zaninovic, N.; Hajirasouliha, I.

10.1101/394882 — bioinformatics — Posted on 2018-08-20

1097 MultiPLIER: a transfer learning framework reveals systemic features of rare autoimmune disease

Taroni, J. N.; Grayson, P. C.; Hu, Q.; Eddy, S.; Kretzler, M.; Merkel, P. A.; Greene, C. S.

10.1101/395947 — bioinformatics — Posted on 2018-08-20

1098 Decomposing cell identity for transfer learning across cellular measurements, platforms, tissues, and species.

Stein-O'Brien, G. L.; Clark, B. S.; Sherman, T.; Zibetti, C.; Hu, Q.; Sealfon, R.; Liu, S.; Qian, J.; Colantuoni, C.; Blackshaw, S.; Goff, L. A.; Fertig, E. J.

10.1101/395004 — bioinformatics — Posted on 2018-08-20

1099 ML-DSP: Machine Learning with Digital Signal Processing for ultrafast, accurate, and scalable genome classification at all taxonomic levels

Randhawa, G.; Hill, K. A.; Kari, L.

10.1101/394932 — genomics — Posted on 2018-08-20

1100 Software tools for automated transmission electron microscopy

Schorb, M.; Haberbosch, I.; Hagen, W.; Schwab, Y.; Mastronarde, D.

10.1101/389502 — cell biology — Posted on 2018-08-20

1101 Learning unsupervised feature representations for single cell microscopy images with paired cell inpainting

Lu, A.; Kraus, O. Z.; Cooper, S.; Moses, A. M.

10.1101/395954 — bioinformatics — Posted on 2018-08-20

1102 Burst Synchronization in A Scale-Free Neuronal Network with Inhibitory Spike-Timing-Dependent Plasticity

Kim, S.-Y.; Lim, W.

10.1101/321562 — neuroscience — Posted on 2018-08-20

1103 Unilateral optogenetic inhibition and excitation of basal ganglia output show opposing effects on directional lick choices and movement initiation in mice

Morrissette, A.; Chen, P.-H.; Bhamani, C.; Borden, P. Y.; Waiblinger, C.; Stanley, G. B.; Jaeger, D.

10.1101/360818 — neuroscience — Posted on 2018-08-20

1104 Poor coherence in older people’s speech is explained by impaired semantic and executive processes

Hoffman, P.; Loginova, E.; Russell, A.

10.1101/320473 — neuroscience — Posted on 2018-08-20

1105 MEG sensor patterns reflect perceptual but not categorical similarity of animate and inanimate objects

Proklova, D.; Kaiser, D.; Peelen, M. V.

10.1101/238584 — neuroscience — Posted on 2018-08-20

1106 Global analysis of specificity determinants in eukaryotic protein kinases

Bradley, D.; Vieitez, C.; Rajeeve, V.; Cutillas, P. R.; Beltrao, P.

10.1101/195115 — cell biology — Posted on 2018-08-20

1107 Synchronization of Hes1 oscillations coordinate and refine condensation formation and patterning of the avian limb skeleton

Bhat, R.; Glimm, T.; Linde-Medina, M.; Cui, C.; Newman, S.

10.1101/157446 — developmental biology — Posted on 2018-08-20

1108 A non-dimensional, two-parameter mechanical model reveals alterations in nuclear mechanics upon Hepatitis C Virus infection

Balakrishnan, S.; Mathad, S.; Sharma, G.; Raju, S.; Reddy, U. B.; Das, S.; Ananthasuresh, G. K.

10.1101/395129 — biophysics — Posted on 2018-08-19

1109 Modeling of CD16, 2B4 and NKG2D stimulation in natural killer cell activation

Makaryan, S. Z.; Finley, S. D.

10.1101/395756 — systems biology — Posted on 2018-08-19

1110 DNA-PKcs promotes DNA end processing

Deshpande, R.; Myler, L.; Soniat, M.; Lee, L.; Lees-Miller, S.; Finkelstein, I.; Paull, T. T.

10.1101/395731 — molecular biology — Posted on 2018-08-19

1111 Clustering of the structures of protein kinase activation loops: A new nomenclature for active and inactive kinase structures

Modi, V.; Dunbrack, R. L.

10.1101/395723 — bioinformatics — Posted on 2018-08-19

1112 Imaging Striatal Dopamine Release Using a Non-Genetically Encoded Near-Infrared Fluorescent Catecholamine Nanosensor

Beyene, A. G.; Delevich, K.; Del Bonis ODonnell, J. T.; Piekarski, D. J.; Lin, W. C.; Thomas, A. W.; Yang, S. J.; Kosillo, P.; Yang, D.; Wilbrecht, L.; Landry, M. P.

10.1101/356543 — neuroscience — Posted on 2018-08-19

1113 MicroRNA regulation of CTP synthase and cytoophidium in Drosophila melanogaster

Dzaki, N.; Woo, W.-K.; Azzam, G.

10.1101/393181 — cell biology — Posted on 2018-08-19

1114 Native and invading yellow starthistle (Centaurea solstitialis) microbiomes differ in composition and diversity of bacteria

Lu-Irving, P.; Harencar, J.; Sounart, H.; Welles, S. R.; Swope, S. M.; Baltrus, D. A.; Dlugosch, K. M.

10.1101/119917 — plant biology — Posted on 2018-08-19

1115 Task complexity interacts with state-space uncertainty in the arbitration process between model-based and model-free reinforcement-learning at both behavioral and neural levels

Kim, D.; Park, G. Y.; O'Doherty, J. P.; Lee, S. W.

10.1101/393983 — neuroscience — Posted on 2018-08-19

1116 Genomic Surveillance for Antimicrobial Resistance in Mannheimia haemolytica Using Nanopore Single Molecule Sequencing Technology

Lim, A.; Naidenov, B.; Bates, H.; Willyerd, K.; Snider, T.; Couger, M. B.; Chen, C.; Ramachandran, A.

10.1101/395087 — microbiology — Posted on 2018-08-19

1117 An integrative genomic analysis of the Longshanks selection experiment for longer limbs in mice

Castro, J. L. P.; Yancoskie, M. N.; Marchini, M.; Belohlavy, S.; Kucka, M.; Beluch, W. H.; Naumann, R.; Skuplik, I.; Cobb, J.; Barton, N. H.; Rolian, C.; Chan, Y. F.

10.1101/378711 — evolutionary biology — Posted on 2018-08-19

1118 High-throughput Genotype based Population Structure Analysis of Selected Buffalo Breeds

Thakor, P. B.; Hinsu, A. T.; Bhatia, D. R.; Shah, T. M.; Nayee, N.; Sudhakar, A.; Joshi, C. G.

10.1101/395681 — genomics — Posted on 2018-08-19

1119 The global distribution of Bacillus anthracis and associated anthrax risk to humans, livestock, and wildlife

Carlson, C. J.; Kracalik, I.; Ross, N.; Alexander, K.; Hugh-Jones, M. E.; Fegan, M.; Elkin, B.; Epp, T.; Shury, T.; Bagirova, M.; Getz, W. M.; Blackburn, J. K.

10.1101/394023 — epidemiology — Posted on 2018-08-19

1120 Herd protection against Plasmodium falciparum infections conferred by mass antimalarial drug administrations and the implications for malaria elimination

Parker, D. M.; Tun, S. T. T.; White, L.; Kajeechiwa, L.; Thwin, M. M.; Landier, J.; Chaumeau, V.; Corbel, V.; Dondorp, A. M.; von Seidlein, L.; White, N. J.; Maude, R. J.; Nosten, F. H.

10.1101/393843 — epidemiology — Posted on 2018-08-19

1121 Herd Immunity Alters the Conditions for Performing Dose Schedule Comparisons: An Individual-based Model of Pneumococcal Carriage

Yang, A.; Cai, F.; Lipsitch, M.

10.1101/393108 — epidemiology — Posted on 2018-08-19

1122 Morphogenetic processes as data: Quantitative structure in the Drosophila eye imaginal disc

Alicea, B.; Portegys, T. E.; Gordon, D.; Gordon, R.

10.1101/395640 — developmental biology — Posted on 2018-08-19

1123 Nonlinear processing of shape information in rat lateral extrastriate cortex

Matteucci, G.; Bellacosa Marotti, R.; Rosselli, F. B.; Zoccolan, D.

10.1101/341792 — neuroscience — Posted on 2018-08-19

1124 Two-antibody pan-ebolavirus cocktail confers broad therapeutic protection in ferrets and nonhuman primates

Bornholdt, Z. A.; Herbert, A. S.; Mire, C. E.; He, S.; Cross, R. W.; Wec, A. Z.; Abelson, D. M.; Geisbert, J. B.; James, R. M.; Rahim, M. N.; Zhu, W.; Borisevich, V.; Banadyga, L.; Gunn, B. M.; Agans, K. N.; Goodwin, E.; Tierney, K.; Shestowsky, W. S.; Bohorov, O.; Bohorova, N.; Velasco, J.; Ailor, E.; Kim, D. H.; Pauly, M. H.; Whaley, K. J.; Alter, G.; Walker, L. M.; Chandran, K.; Zeitlin, L.; Qiu, X.; Geisbert, T. W.; Dye, J. M.

10.1101/395533 — microbiology — Posted on 2018-08-19

1125 Dynamic representations of behaviourally relevant features support rapid face processing in the human ventral visual stream

Dima, D. C.; Singh, K. D.

10.1101/394916 — neuroscience — Posted on 2018-08-19

1126 High-dose rifamycins enable shorter oral treatment in a murine model of Mycobacterium ulcerans disease

Omansen, T. F.; Almeida, D.; Converse, P. J.; Li, S.-Y.; Lee, J.; Stienstra, Y.; van der Werf, T. S.; Grosset, J. H.; Nuermberger, E.

10.1101/395095 — microbiology — Posted on 2018-08-19

1127 Novel cholera toxin variant and ToxT regulon in environmental Vibrio mimicus strains: potential resources for the evolution of Vibrio cholerae hybrid strains

Neogi, S. B.; Chowdhury, N.; Awasthi, S. P.; Asakura, M.; Mahmud, Z. H.; Islam, M. S.; Hinenoya, A.; Nair, G. B.; Yamasaki, S.

10.1101/395061 — microbiology — Posted on 2018-08-19

1128 Streptococcal superantigen-induced expansion of human tonsil T cells leads to altered T follicular helper cell phenotype, B cell death, and reduced immunoglobulin release

Davies, F. J.; Olme, C.; Lynskey, N. N.; Turner, C. E.; Sriskandan, S.

10.1101/395608 — microbiology — Posted on 2018-08-19

1129 Low-cost and clinically applicable copy number profiling using repeat DNA

Abujudeh, S.; Zeki, S. S.; van Lanschot, M. C.; Pusung, M.; Weaver, J. M.; Li, X.; Noorani, A.; Metz, A. J.; Bornschein, J.; Bower, L.; Miremadi, A.; Fitzgerald, R. C.; Morrissey, E. R.; Lynch, A. G.; the Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium,

10.1101/394429 — genomics — Posted on 2018-08-19

1130 Transcriptome Analysis of Distinct Cold Tolerance Strategies in the Rubber Tree (Hevea brasiliensis)

Campos Mantello, C.; Boatwright, L.; da Silva, C. C.; Scaloppi, E. J.; de Souza Goncalves, P.; Barbazuk, W. B.; de Souza, A. P.

10.1101/395590 — plant biology — Posted on 2018-08-19

1131 Cycad coralloid roots contain bacterial communities including cyanobacteria and Caulobacter spp that encode niche-specific biosynthetic gene clusters

Gutierrez-Garcia, K.; Bustos-Diaz, E. D.; Corona-Gomez, J. A.; Ramos-Aboites, H. E.; Selem-Mojica, N.; Cruz-Morales, P.; Perez-Farrera, M. A.; Barona-Gomez, F.; Cibrian-Jaramillo, A.

10.1101/121160 — evolutionary biology — Posted on 2018-08-19

1132 Entrainment and maintenance of an internal metronome in premotor cortex

Cadena-Valencia, J.; Garcia-Garibay, O.; Merchant, H.; Jazayeri, M.; de Lafuente, V.

10.1101/394783 — neuroscience — Posted on 2018-08-19

1133 Opposing effects of prostaglandin receptor EP2 signaling in mouse immune cells and neurons after status epilepticus

Varvel, N. H.; Chen, D.; Biegel, A.; Dingledine, R.

10.1101/395566 — neuroscience — Posted on 2018-08-19

1134 Mesenchymal stem cells protect retinal ganglion cells from degeneration via mitochondrial donation

JIANG, D.; Feng, H.; Zhang, Z.; Yan, B.; Chen, L.; Ma, C.; Li, C.; Han, S.; Zhang, Y.; Chen, P.; Tse, H.-F.; Fu, Q.; Chiu, K.; Lian, Q.

10.1101/393959 — cell biology — Posted on 2018-08-19

1135 A Proof-of-Principle of Nanoscale Optogenetics

Stahlberg, M. A.; Ramakrishnan, C.; Willig, K. I.; Boyden, E. S.; Deisseroth, K.; Dean, C.

10.1101/395475 — neuroscience — Posted on 2018-08-19

1136 H3K9me3 is Required for Transgenerational Inheritance of Small RNAs that Target a Unique Subset of Newly Evolved Genes

Lev, I.; Gingold, H.; Rechavi, O.

10.1101/338582 — genetics — Posted on 2018-08-19

1137 Decoupling from yolk sac is required for extraembryonic tissue spreading in the scuttle fly Megaselia abdita.

Caroti, F.; Gonzalez Avalos, E.; Noeske, V.; Gonzalez Avalos, P.; Kromm, D.; Wosch, M.; Schütz, L.; Hufnagel, L.; Lemke, S.

10.1101/236364 — evolutionary biology — Posted on 2018-08-19

1138 Cartilaginous and osteochondral tissue formation by human mesenchymal stem cells on three-dimensionally woven scaffolds

Larson, B. L.; Yu, S. N.; Park, H.; Estes, B. T.; Moutos, F. T.; Bloomquist, C. J.; Wu, P. B.; Welter, J. F.; Langer, R.; Guilak, F.; Freed, L. E.

10.1101/395202 — bioengineering — Posted on 2018-08-19

1139 Rapid Eye Movement sleep deprivation of rat generates ROS in the hepatocytes and make them more susceptible to oxidative stress

Pandey, A.; Kar, S.

10.1101/375683 — molecular biology — Posted on 2018-08-19

1140 Structural Basis of Broad Ebolavirus Neutralization by a Human Survivor Antibody

West, B. R.; Wec, A. Z.; Moyer, C. L.; Fusco, M. L.; Illinykh, P. A.; Huang, K.; James, R.; Herbert, A.; Hui, S.; Wirchnianski, A. S.; Goodwin, E.; Aman, M. J.; Walker, L. M.; Dye, J. M.; Bukreyev, A.; Chandran, K.; Saphire, E. O.

10.1101/394502 — immunology — Posted on 2018-08-19

1141 Mosaic deletion patterns of the human antibody heavy chain gene locus as revealed by Bayesian haplotyping

Gidoni, M.; Snir, O.; Peres, A.; Polak, P.; Lindeman, I.; Mikocziova, I.; Sarna, V. K.; Lundin, K. E. A.; Clouser, C.; Vigneault, F.; Collins, A. M.; Sollid, L. M.; Yaari, G.

10.1101/314476 — genomics — Posted on 2018-08-19

1142 A prize-collecting Steiner tree application for signature selection to stratify diffuse large B-cell lymphoma subtypes

Akhmedov, M.; Galbusera, L.; Montemanni, R.; Bertoni, F.; Kwee, I.

10.1101/272294 — bioinformatics — Posted on 2018-08-19

1143 Grapevine virus L: a Novel Vitivirus in Grapevine

Debat, H. J.; Zavallo, D.; Brisbane, R. S.; Voncina, D.; Almeida, R. P.; Blouin, A. G.; Al Rwahnih, M.; Gomez-Talquenca, S.; Asurmendi, S.

10.1101/314674 — plant biology — Posted on 2018-08-19

1144 Single cell RNA-seq study of wild type and Hox9,10,11 mutant developing uterus

Potter, S. S.; Mucenski, M. L.; Mahoney, R.; Adam, M.; Potter, A. S.

10.1101/395574 — developmental biology — Posted on 2018-08-19

1145 Developmental Effects of the Pesticide Imidacloprid on Zebrafish Body Length and Mortality

Krishnan, A.; Clyburn, C.; Newcombe, P.

10.1101/395327 — developmental biology — Posted on 2018-08-19

1146 A simple chromogenic whole-cell arsenic biosensor based on Bacillus subtilis

Wicke, N.; Radford, D. S.; French, C. E.

10.1101/395178 — synthetic biology — Posted on 2018-08-19

1147 Whole-neuron synaptic mapping reveals local balance between excitatory and inhibitory synapse organization

Iascone, D. M.; Li, Y.; Sumbul, U.; Doron, M.; Chen, H.; Andreu, V.; Goudy, F.; Segev, I.; Peng, H.; Polleux, F.

10.1101/395384 — neuroscience — Posted on 2018-08-19

1148 Variations in the phagosomal environment of human neutrophils and mononuclear phagocyte subsets.

Foote, J. R.; Patel, A. A.; Yona, S.; Segal, A. W.

10.1101/394619 — immunology — Posted on 2018-08-19

1149 Molecular structure and function of myelin protein P0 in membrane stacking

Raasakka, A.; Ruskamo, S.; Kowal, J.; Han, H.; Baumann, A.; Myllykoski, M.; Fasano, A.; Rossano, R.; Riccio, P.; Buerck, J.; Ulrich, A. S.; Stahlberg, H.; Kursula, P.

10.1101/395491 — biochemistry — Posted on 2018-08-19

1150 Xolotl: An Intuitive and Approachable Neuron and Network Simulator for Research and Teaching

Gorur-Shandilya, S.; Hoyland, A.; Marder, E.

10.1101/394973 — neuroscience — Posted on 2018-08-18

1151 Response Inhibition in Adolescents is Moderated by Brain Connectivity and Social Network Structure

Tompson, S. H.; Falk, E. B.; O'Donnell, M. B.; Cascio, C. N.; Bayer, J. B.; Vettel, J. M.; Bassett, D. S.

10.1101/395038 — neuroscience — Posted on 2018-08-18

1152 Distinct structure of cortical population activity on fast and infraslow timescales

Okun, M.; Steinmetz, N. A.; Lak, A.; Dervinis, M.; Harris, K. D.

10.1101/395251 — neuroscience — Posted on 2018-08-18

1153 Whole brain imaging reveals distinct spatial patterns of amyloid beta deposition in three mouse models of Alzheimer’s disease

Whitesell, J. D.; Buckley, A. R.; Knox, J. E.; Kuan, L.; Graddis, N.; Pelos, A.; Mukora, A.; Wakeman, W.; Bohn, P.; Ho, A.; Hirokawa, K. E.; Harris, J. A.

10.1101/395236 — neuroscience — Posted on 2018-08-18

1154 A diencephalic pathway for movement initiation and rescue of Parkinsonian symptoms

Watson, G. D. R.; Hughes, R. N.; Petter, E. A.; Yin, H.

10.1101/395277 — neuroscience — Posted on 2018-08-18

1155 Elevated P2x7r and P2x4r transcripts levels in the Flinders Sensitive Line Rats, a genetic animal model of depression

Ribeiro, D. E.; Muller, H. K.; Elfving, B.; Joca, S. R. L.; Wegener, G.

10.1101/395194 — neuroscience — Posted on 2018-08-18

1156 Challenge data set for macromolecular multi-microcrystallography

Holton, J. M.

10.1101/394965 — biophysics — Posted on 2018-08-18

1157 GenFam: A web application for gene family-based classification and functional enrichment analysis of plant genomes

Bedre, R.; Mandadi, K.

10.1101/272187 — bioinformatics — Posted on 2018-08-18

1158 Cartilaginous and osteochondral tissue formation by human mesenchymal stem cells on three-dimensionally woven scaffolds

Larson, B. L.; Yu, S. N.; Park, H.; Estes, B. T.; Moutos, F. T.; Bloomquiest, C. J.; Wu, P. B.; Welter, J. F.; Langer, R.; Guilak, F.; Freed, L. E.

10.1101/395202 — bioengineering — Posted on 2018-08-18

1159 Determining protein structures using genetics

Schmiedel, J.; Lehner, B.

10.1101/303875 — systems biology — Posted on 2018-08-18

1160 Rapid Eye Movement sleep deprivation of rat generates ROS in the hepatocytes and make them more susceptible to oxidative stress

Pandey, A.; Kar, S.

10.1101/375683 — molecular biology — Posted on 2018-08-18

1161 MicroRNA regulation of CTP synthase and cytoophidium in Drosophila melanogaster

Woo, W.-K.; Dzaki, N.; Azzam, G.

10.1101/393181 — cell biology — Posted on 2018-08-18

1162 Protein-Ligand Docking with Protein-based and Ligand-based Structure Activity Relationships

Fu, D. Y.; Meiler, J.

10.1101/394874 — biophysics — Posted on 2018-08-18

1163 Distinct higher-order thalamic circuits channel parallel streams of visual information in mice

Bennett, C.; Gale, S. D.; Garrett, M. E.; Newton, M. L.; Callaway, E. M.; Murphy, G. J.; Olsen, S. R.

10.1101/395244 — neuroscience — Posted on 2018-08-18

1164 On the importance of time scales when studying adaptive evolution

Perrier, C.; Charmantier, A.

10.1101/269175 — evolutionary biology — Posted on 2018-08-18

1165 Higher order assembling of the mycobacterial essential polar growth factor DivIVA/Wag31

Choukate, K.; Gupta, A.; Basu, B.; Virk, K.; Ganguli, M.; Chaudhuri, B.

10.1101/394452 — biophysics — Posted on 2018-08-18

1166 Cortical Actomyosin Flows are Generated by Actomyosin Cluster Vibrations in Vitro

Vogel, S.; Woelfer, C.; Ramirez, D. A.; Flassig, R. J.; Sundmacher, K.; Schwille, P.

10.1101/394700 — synthetic biology — Posted on 2018-08-18

1167 Programmed mutation of liver fluke granulin using CRISPR/Cas9 attenuates virulence of infection-induced hepatobiliary morbidity

Arunsan, P.; Ittiprasert, W.; Smout, M. J.; Cochran, C. J.; Mann, V. H.; Chaiyadet, S.; Karinshak, S. E.; Sripa, B.; Young, N. D.; Sotillo, J.; Loukas, A.; Brindley, P. J.; Laha, T.

10.1101/386219 — molecular biology — Posted on 2018-08-18

1168 The aphelid-like phagotrophic origins of fungi

Torruella, G.; Grau-Bove, X.; Moreira, D.; Karpov, S. A.; Burns, J.; Sebe-Pedros, A.; Volcker, E.; Lopez-Garcia, P.

10.1101/233882 — evolutionary biology — Posted on 2018-08-17

1169 Triggering visually-guided behavior by holographic activation of pattern completion neurons in cortical ensembles

Carrillo-Reid, L.; Han, S.; Yang, W.; Akrouh, A.; Yuste, R.

10.1101/394999 — neuroscience — Posted on 2018-08-17

1170 A Gene Regulatory Model of Cortical Neurogenesis

Pfister, S.; Hauri, A.; Zubler, F.; Michel, G.; Kennedy, H.; DeHay, C.; Douglas, R.

10.1101/394734 — neuroscience — Posted on 2018-08-17

1171 Neuronal constituents and putative interactions within the Drosophila ellipsoid body neuropil

Omoto, J. J.; Nguyen, B.-C. M.; Kandimalla, P.; Lovick, J. K.; Donlea, J. M.; Hartenstein, V.

10.1101/394833 — neuroscience — Posted on 2018-08-17

1172 Status of urban feral cats Felis catus in England: A comparative study

Askew, N. P.; Vial, F.; Smith, G. C.

10.1101/394643 — zoology — Posted on 2018-08-17

1173 Gut microbiota composition explains more variance in the host cardiometabolic risk than genetic ancestry

Guzman-Castaneda, S. J.; Ortega-Vega, E. L.; de la Cuesta-Zuluaga, J.; Velasquez-Mejia, E. P.; Rojas, W.; Bedoya, G.; Escobar, J. S.

10.1101/394726 — microbiology — Posted on 2018-08-17

1174 Genome-Wide Reconstitution of Chromatin Transactions: RSC Preferentially disrupts H2A.Z-Containing Nucleosomes

Cakiroglu, A.; Clapier, C.; Ehrensberger, A.; Darbo, E.; Cairns, B.; Luscombe, N.; Svejstrup, J.

10.1101/394692 — biochemistry — Posted on 2018-08-17

1175 Characterization of osteoarthritis phenotypes by global metabolomic profiling of human synovial fluid

Carlson, A. K.; Rawle, R. A.; Wallace, C. W.; Brooks, E. G.; Adams, E.; Greenwood, M. C.; Olmer, M.; Lotz, M.; Bothner, B.; June, R.

10.1101/395020 — pathology — Posted on 2018-08-17

1176 Sae2/CtIP prevents R-loop accumulation in eukaryotic cells

Makharashvili, N.; Arora, S.; Yin, Y.; Fu, Q.; Leung, J.; Miller, K.; Paull, T. T.

10.1101/394924 — molecular biology — Posted on 2018-08-17

1177 Extensive Secondary Contact Among Three Glacial Lineages of Arctic Char (Salvelinus alpinus) in Newfoundland and Labrador

Salisbury, S. J.; McCracken, G. R.; Keefe, D.; Perry, R.; Ruzzante, D. E.

10.1101/394742 — evolutionary biology — Posted on 2018-08-17

1178 Centromeric CENP-A loading requires accurate mitotic timing, which is linked to checkpoint proteins

Erhardt, S.; Pauleau, A.-L.; Bergner, A.; Kajtez, J.

10.1101/394981 — cell biology — Posted on 2018-08-17

1179 Genome Analyses of a New Mycoplasma Species From the scorpion Centruroides vittatus.

Yamashita, T.; Rhoads, D. D.; Pummill, J.

10.1101/394825 — genomics — Posted on 2018-08-17

1180 DECENT: Differential Expression with Capture Efficiency AdjustmeNT for Single-Cell RNA-seq Data

Ye, C.; Speed, T. P.; Salim, A.

10.1101/225177 — genomics — Posted on 2018-08-17

1181 Transcriptional Activation of Elephant Shark Mineralocorticoid Receptor by Corticosteroids, Progestins and Spironolactone

Katsu, Y.; Kohno, S.; Oka, K.; Lin, X.; Otake, S.; Pillai, N. E.; Takagi, W.; Hyodo, S.; Venkatesh, B.; Baker, M. E.

10.1101/265348 — evolutionary biology — Posted on 2018-08-17

1182 Importance of vitamin D in critically ill children with subgroup analyses of sepsis and respiratory tract infections: a systematic review and meta-analysis

Cariolou, M.; Cupp, M. A.; Evangelou, E.; Tzoulaki, I.; Berlanga-Taylor, A. J.

10.1101/390476 — epidemiology — Posted on 2018-08-17

1183 Plasticity of Mitochondrial DNA Inheritance and its Impact on Nuclear Gene Transcription in Yeast Hybrids

Hewitt, S. K.; Dungrattanalert, K.; Burgis, T.; Zeef, L. A.; Delneri, D.

10.1101/394858 — genomics — Posted on 2018-08-17

Baker, C.; Ebsch, C.; Lampl, I.; Rosenbaum, R.

10.1101/372607 — neuroscience — Posted on 2018-08-17

1185 Induction of the BIM Short Splice Variant Sensitizes Proliferating NK Cells to IL-15 Withdrawal

Jacobs, B.; Pfefferle, A.; Clement, D.; Goodridge, J. P.; Saetersmoen, M. L.; Lorenz, S.; Wiiger, M. T.; Malmberg, K.-J.

10.1101/392985 — immunology — Posted on 2018-08-17

1186 Impact of Sexual Transmission to Sex-specific Attack Rates in Zika Epidemics

Barros, A. C.; Santos, K.; Massad, E.; Coelho, F. C.

10.1101/347104 — epidemiology — Posted on 2018-08-17

1187 Three-photon light-sheet fluorescence microscopy

Escobet-Montalban, A.; Gasparoli, F. M.; Nylk, J.; Liu, P.; Yang, Z.; Dholakia, K.

10.1101/323790 — cell biology — Posted on 2018-08-17

1188 Extreme copy number variation at a tRNA ligase affecting phenology and fitness in yellow monkeyflowers

Nelson, T. C.; Monnahan, P.; McIntosh, M.; Finseth, F.; Anderson, K.; Macarthur-Waltz, E.; Kelly, J. K.; Fishman, L.

10.1101/392183 — evolutionary biology — Posted on 2018-08-17

1189 Ultrafast clustering of single-cell flow cytometry data using FlowGrid

Ye, X.; Ho, J. W. K.

10.1101/394189 — bioinformatics — Posted on 2018-08-17

1190 Biogeography masks diet-induced shifts in the bacterial community associated with larvae of the sea urchin Strongylocentrotus droebachiensis

Carrier, T.; Dupont, S.; Reitzel, A.

10.1101/394486 — ecology — Posted on 2018-08-17

1191 NaPi-IIb as a potential diagnostic and prognostic biomarker in ovarian cancers

Zhao, S.; Wang, Z.

10.1101/394759 — cancer biology — Posted on 2018-08-17

1192 Phylogeny and distinct properties of major intrinsic proteins in the genomes of six Phytophthora species suggest their novel functions in Phytophthora

Azad, M. A. K.; Ahmed, J.; Hakim, A.; Hasan, M. M.; Alum, M. A.; Hasan, M.; Ishikawa, T.; Sawa, Y.

10.1101/394395 — bioinformatics — Posted on 2018-08-17

1193 New Statistical Methods for Constructing Robust Differential Correlation Networks

Yu, D.; Zhang, Z.; Glass, K.; Su, J.; DeMeo, D. L.; Tantisira, K.; Weiss, S. T.; Qiu, W.

10.1101/393991 — bioinformatics — Posted on 2018-08-17

1194 Integrating Mendelian randomization and multiple-trait colocalization to uncover cell-specific inflammatory drivers of autoimmune and atopic disease

McGowan, L. M.; Davey Smith, G.; Gaunt, T. R.; Richardson, T. G.

10.1101/394296 — genetics — Posted on 2018-08-17

1195 Dispersal routes of climate-induced marine range expansions into the Arctic

Andrews, A. J.; Christiansen, J. S.; Bhat, S.; Lynghammar, A.; Westgaard, J.-I.; Pampoulie, C.; Praebel, K.

10.1101/394346 — ecology — Posted on 2018-08-17

1196 Density-dependent changes in neophobia and stress-coping styles in the worlds oldest farmed fish

Champneys, T.; Castaldo, G.; Consuegra, S.; Garcia de Leaniz, C.

10.1101/394288 — animal behavior and cognition — Posted on 2018-08-17

1197 Germ-free mice exhibit mast cells with impaired functionality and gut homing and do not develop food allergy

Schwarzer, M.; Hermanova, P.; Srutkova, D.; Golias, J.; Hudcovic, T.; Sinkora, M.; Akgun, J.; Zwicker, C.; Wiedermann, U.; Tuckova, L.; Kozakova, H.; Schabussova, I.

10.1101/394213 — immunology — Posted on 2018-08-17

1198 SiCloneFit: Bayesian inference of population structure, genotype, and phylogeny of tumor clones from single-cell genome sequencing data

Zafar, H.; Navin, N.; Chen, K.; Nakhleh, L.

10.1101/394262 — genomics — Posted on 2018-08-17

1199 Assessing natural selection during range expansions: Insights from a spatially explicit ABC study

Kanitz, R.; Neuenschwander, S.; Goudet, J.

10.1101/391110 — evolutionary biology — Posted on 2018-08-17

1200 Quorums enable optimal pooling of independent judgements

Marshall, J. A. R.; Kurvers, R. H. J. M.; Krause, J.; Wolf, M.

10.1101/394460 — ecology — Posted on 2018-08-17

1201 Characterization of segmental duplications and large inversions using Linked-Reads

Karaoglanoglu, F.; Ricketts, C.; Eslami Rasekh, M.; Ebren, E.; Hajirasouliha, I.; Alkan, C.

10.1101/394528 — bioinformatics — Posted on 2018-08-17

1202 Efficient Multivariate Analysis Algorithms for Longitudinal Genome-wide Association Studies

Ning, C.; Wang, D.; Zhou, L.; Kang, H.; Zhang, S.; Yang, J.; Liu, J.-F.

10.1101/394197 — bioinformatics — Posted on 2018-08-17

1203 Characterization of novel TMEM173 mutation with additive IFIH1 risk allele

Keskitalo, S.; Haapaniemi, E.; Einarsdottir, E.; Rajamaki, K.; Heikkila, H.; Ilander, M.; Poyhonen, M.; Morgunova, E.; Hokynar, K.; Lagstrom, S.; Kivirikko, S.; Mustjoki, S.; Eklund, K.; Saarela, J.; Kere, J.; Seppanen, M.; Ranki, A.; Hannula-Jouppi, K.; Varjosalo, M.

10.1101/394353 — immunology — Posted on 2018-08-17

1204 Bradycardic mice undergo effective heart rate improvement after specific homing to the sino-atrial node and differentiation of adult muscle derived stem cells.

Mesirca, P.; Mamaeva, D.; Bidaud, I.; Davase, R.; DiFrancesco, M. L.; Mitutsova, V.; Torrente, A. G.; Arsic, N.; Nargeot, J.; Striessnig, J.; Lee, A.; Lamb, N.; Mangoni, M.; Fernandez, A.

10.1101/393512 — cell biology — Posted on 2018-08-17

1205 Bacterial community dynamics during embryonic and larval development of three confamilial echinoids

Carrier, T.; Reitzel, A.

10.1101/394478 — developmental biology — Posted on 2018-08-17

1206 SOL1 and SOL2 Regulate Fate Transition and Cell Divisions in the Arabidopsis Stomatal Lineage

Simmons, A. R.; Davies, K. A.; Wang, W.; Liu, Z.; Bergmann, D. C.

10.1101/394940 — developmental biology — Posted on 2018-08-17

1207 Systematic domain-based aggregation of protein structures highlights DNA-, RNA-, and other ligand-binding positions

Kobren, S. N.; Singh, M.

10.1101/394494 — bioinformatics — Posted on 2018-08-17

1208 Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic forms of autism in postmortem human brain tissue.

Wong, C.; Smith, R.; Hannon, E.; Ramaswami, G.; Parikshak, N.; Assary, E.; Troakes, C.; Poschmann, J.; Schalkwyk, L.; Sun, W.; Prabhakar, S.; Geschwind, D. H.; Mill, J.

10.1101/394387 — genomics — Posted on 2018-08-17

1209 The neural dynamics of familiar face recognition

Ambrus, G. G.; Kaiser, D.; Cichy, R.; Kovacs, G.

10.1101/393652 — neuroscience — Posted on 2018-08-17

1210 Environmental DNA for the enumeration and management of Pacific salmon

Levi, T.; Allen, J. M.; Bell, D.; Joyce, J.; Russell, J. R.; Tallmon, D. A.; Vulstek, S. C.; Yang, C.; Yu, D. W.

10.1101/394445 — ecology — Posted on 2018-08-17

1211 Length-independent telomere damage drives cardiomyocyte senescence

Anderson, R.; Lagnado, A.; Maggiorani, D.; Walaszczyk, A.; Dookun, E.; Chapman, J.; Birch, J.; Salmonowicz, H.; Ogrodnik, M.; Jurk, D.; Proctor, C.; Correia-Melo, C.; Victorelli, S.; Fielder, E.; Berlinguer-Palmini, R.; Owens, W. A.; Greaves, L.; Kolsky, K.; Parini, A.; Douin-Echinard, V.; LeBrasseur, N.; Arthur, H.; Tual-Chalot, S.; Schafer, M.; Roos, C.; Miller, J.; Robertson, N.; Mann, J.; Adams, P. D.; Tchkonia, T.; Kirkland, J. L.; Mialet-Perez, J.; Richardson, G. D.; Passos, J. F.

10.1101/394809 — cell biology — Posted on 2018-08-17

1212 Therapeutic potential of TAF1 bromodomains for cancer treatment

Garcia-Carpizo, V.; Ruiz-Llorente, S.; Sarmentero, J.; Barrero, M. J.

10.1101/394254 — cancer biology — Posted on 2018-08-17

1213 In silico Drug Repositioning of bortezomib to reverse metastatic effect of GALNT14 in lung cancer

Cha, H.-J.; Kwon, O.-S.; Lee, H.; Kong, H.-J.; Park, J. E.; Lee, W.; Kang, S.; Kim, M.; Kim, W.

10.1101/394163 — cancer biology — Posted on 2018-08-17

1214 A map of direct TF-DNA interactions in the human genome

Gheorghe, M.; Sandve, G. K.; Khan, A.; Cheneby, J.; Ballester, B.; Mathelier, A.

10.1101/394205 — bioinformatics — Posted on 2018-08-17

1215 rawMSA: Proper Deep Learning makes protein sequence profiles and feature extraction obsolete

Mirabello, C.; Wallner, B.

10.1101/394437 — bioinformatics — Posted on 2018-08-17

1216 Metabolic engineering of Escherichia coli for de novo biosynthesis of vitamin B12

Fang, H.; Li, D.; Kang, J.; Jiang, P.; Sun, J.; Zhang, D.

10.1101/394338 — synthetic biology — Posted on 2018-08-17

1217 Suppression of p16 increases nucleotide synthesis via mTORC1

Buj, R.; Kuskovsky, R.; Dahl, E. S.; Leon, K. E.; Maglakelidze, N.; Navaratnarajah, M.; Zhang, G.; Doan, M. T.; Jiang, H.; Kutzler, L.; Lacko, H.; Lu, Y.; Mills, G. B.; Gowda, R.; Robertson, G. P.; Herlyn, M.; Imamura, Y.; Kimball, S.; Snyder, N. W.; Aird, K. M.

10.1101/393876 — cancer biology — Posted on 2018-08-17

1218 CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers

Menny, A.; Serna, M.; Boyd, C. M.; Gardner, S.; Joseph, A. P.; Morgan, B. P.; Topf, M.; Brooks, N. J.; Bubeck, D.

10.1101/392563 — biophysics — Posted on 2018-08-17

1219 Capturing the spatiotemporal dynamics of task-initiated thoughts with combined EEG and fMRI

Brechet, L.; Brunet, D.; Birot, G.; Gruetter, R.; Michel, C. M.; Jorge, J.

10.1101/346346 — neuroscience — Posted on 2018-08-17

1220 Ab initio derivation of the FRET equations resolves old puzzles and suggests measurement strategies

Raicu, V.

10.1101/394635 — biophysics — Posted on 2018-08-17

1221 Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

Pulit, S. L.; Weng, L.-C.; McArdle, P. F.; Trinquart, L.; Huan Choi, S.; Mitchell, B. D.; Rosand, J.; de Bakker, P. I.; Benjamin, E. J.; Ellinor, P. T.; Kittner, S. J.; Lubitz, S. A.; Anderson, C. D.; Atrial Fibrillation Genetics Consortium, ; International Stroke Genetics Consortium,

10.1101/239269 — genetics — Posted on 2018-08-17

1222 Learning and Forgetting Using Reinforced Bayesian Change Detection

Moens, V.; Zenon, A.

10.1101/294959 — neuroscience — Posted on 2018-08-17

1223 Learning and Imputation for Mass-spec Bias Reduction (LIMBR)

Crowell, A. M.; Greene, C. S.; Loros, J. J.; Dunlap, J. C.

10.1101/301242 — bioinformatics — Posted on 2018-08-17

1224 Structure of a novel dimeric SET domain methyltransferase that regulates cell motility

Pivovarova, Y.; Liu, J.; Lesigang, J.; Koldyka, O.; Rauschmeier, R.; Hu, K.; Dong, G.

10.1101/264291 — biochemistry — Posted on 2018-08-17

1225 Overt social interaction and resting state in autism: core and contextual neural features

Jasmin, K.; Gotts, S.; Xu, Y.; Liu, S.; Riddell, C.; Ingeholm, J.; Kenworthy, L.; Wallace, G. L.; Braun, A. R.; Martin, A.

10.1101/332213 — neuroscience — Posted on 2018-08-17

1226 Programmed genome editing of the omega-1 ribonuclease of the blood fluke, Schistosoma mansoni

Ittiprasert, W.; Mann, V. H.; Karinshak, S. E.; Coghlan, A.; Rinaldi, G.; Sankaranarayanan, G.; Chaidee, A.; Tanno, T.; Kumkhaek, C.; Prangtaworn, P.; Mentink-Kane, M. J.; Cochran, C. J.; Driguez, P.; Holroyd, N.; Tracey, A.; Rodpai, R. H.; Everts, B.; Hokke, C. H.; Hoffmann, K. F.; Berriman, M.; Brindley, P. J.

10.1101/358424 — molecular biology — Posted on 2018-08-17

1227 Intragenomic Conflict over Bet-Hedging

Wilkins, J. F.; Bhattacharya, T.

10.1101/364190 — evolutionary biology — Posted on 2018-08-17

1228 Predicting the future direction of cell movement with convolutional neural networks

Nishimoto, S.; Tokuoka, Y.; Yamada, T. G.; Hiroi, N.; Funahashi, A.

10.1101/388033 — systems biology — Posted on 2018-08-17

1229 CRISPR/Cas9-mediated gene deletion of the ompA gene in an Enterobacter gut symbiont impairs biofilm formation and reduces gut colonization of Aedes aegypti mosquitoes

Hegde, S.; Nilyanimit, P.; Kozlova, E.; Narra, H. P.; Sahni, S. K.; Hughes, G. L.

10.1101/389957 — microbiology — Posted on 2018-08-17

1230 A nanotube-mediated path to protocell formation

Koksal, E. S.; Liese, S.; Kantarci, I.; Olsson, R.; Carlson, A.; Gozen, I.

10.1101/388405 — biophysics — Posted on 2018-08-17

1231 MeCP2-E1 isoform is a dynamically expressed, weakly DNA-bound protein with different protein and DNA interactions compared to MeCP2-E2

Martinez de Paz, A.; Khajavi, L.; Martin, H.; Claveria-Gimeno, R.; tom Dieck, S.; Cheema, M. S.; Sanchez-Mut, J. V.; Moksa, M.; Carles, A.; Brodie, N.; Sheikh, T. I.; Freeman, M.; Petrotchenko, E.; Borchers, C.; Schuman, E.; Zytnicki, M.; Velazquez-Campoy, A.; Abian, O.; Hirst, M.; Esteller, M.; Vincent, J.; Malnou, C. E.; Ausio, J.

10.1101/392092 — biochemistry — Posted on 2018-08-17

1232 How biological attention mechanisms improve taskperformance in a large-scale visual system model

Lindsay, G. W.; Miller, K. D.

10.1101/233338 — neuroscience — Posted on 2018-08-17

1233 Dual RNA-seq reveals large-scale non-conserved genotype x genotype specific genetic reprograming and molecular crosstalk in the mycorrhizal symbiosis

Sanders, I. R.; Mateus, I. D.; Masclaux, F. G.; Aletti, C.; Rojas, E. C.; Savary, R.; Dupuis, C.

10.1101/393637 — plant biology — Posted on 2018-08-17

1234 Sleep/wake synchronization across latitude

Martin-Olalla, J. M.

10.1101/378737 — physiology — Posted on 2018-08-17

1235 Could future gene therapy prevent aging diseases?

Oliynyk, R.

10.1101/390773 — genetics — Posted on 2018-08-17

1236 The identification of DNA binding regions of the σ54 factor using artificial neural network

Ferreira, L. M.; Raittz, R. T.; Marchaukoski, J. N.; Weiss, V. A.; Santos-Wiess, I. C. R.; Costa, P. A. B.; Voyceik, R.; Rigo, L. U.

10.1101/393736 — bioinformatics — Posted on 2018-08-17

1237 Nuclear Tau modulates VGluT1 expression: a new function for Tau

Siano, G.; Varisco, M.; Caiazza, M. C.; Quercioli, V.; Mainardi, M.; Ippolito, C.; Cattaneo, A.; Di Primio, C.

10.1101/394312 — molecular biology — Posted on 2018-08-17

1238 P-TEFb activation by RBM7 shapes a pro-survival transcriptional response to genotoxic stress

Bugai, A.; Quaresma, A. J.; Friedel, C. C.; Lenasi, V.; Sibley, C. R.; Kukanja, P.; Fujinaga, K.; Blasius, M.; Hennig, T.; Ule, J.; Doelken, L.; Barboric, M.

10.1101/394239 — biochemistry — Posted on 2018-08-17

1239 Beyond financial conflicts of interest: Institutional oversight of faculty consulting agreements at schools of medicine and public health

Mello, M. M.; Murtagh, L.; Joffe, S.; Taylor, P.; Greenberg, Y.; Campbell, E.

10.1101/394585 — scientific communication and education — Posted on 2018-08-17

1240 Electrical synapses regulate both subthreshold and population activity of principal cells in response to transient inputs within canonical feedforward circuits

Haas, J. S.; Pham, T.

10.1101/394593 — neuroscience — Posted on 2018-08-17

1241 Dimensionality in recurrent spiking networks: global trends in activity and local origins in connectivity

recanatesi, s.; Ocker, G.; Buice, M.; Shea-Brown, E.

10.1101/394684 — neuroscience — Posted on 2018-08-17

1242 Fluctuating environments select for short-term phenotypic variation leading to long-term exploration

Canino-Koning, R.; Ofria, C.; Wiser, M.

10.1101/394676 — evolutionary biology — Posted on 2018-08-17

1243 Multi-scale modeling reveals angiogenesis-induced drug resistance in brain tumor and predicts a synergistic drug combination targeting EGFR and VEGFR pathways

Liang, W.; Zhang, J.; Sun, X.

10.1101/394668 — systems biology — Posted on 2018-08-17

1244 Membrane potential resonance in non-oscillatory neurons interacts with synaptic connectivity to produce network oscillations

Rotstein, H.; Bel, A.

10.1101/394650 — neuroscience — Posted on 2018-08-17

1245 Interrogating Mutant Allele Expression via Customized Reference Genomes to Define Influential Cancer Mutations

Grant, A.; Vail, P.; Padi, M.; Witkiewicz, A.; Knudsen, E.

10.1101/394627 — cancer biology — Posted on 2018-08-17

1246 CEACAM1 regulates the IL-6 mediated fever response to LPS through the RP105 receptor in murine monocytes

Zhang, Z.; La Placa, D.; Nguyen, T.; Kujawski, M.; Le, K. M.; Li, L.; Shively, J.

10.1101/394577 — immunology — Posted on 2018-08-17

1247 A Data-driven Individual-based Model of Infectious Disease in Livestock Operation: A Validation Study for Paratuberculosis

Al-Mamun, M. A.; Smith, R. L.; Nigsch, A.; Schukken, Y. H.; Grohn, Y. T.

10.1101/394569 — epidemiology — Posted on 2018-08-17

1248 RT States: systematic annotation of the human genome using cell type-specific replication timing programs

Poulet, A.; Li, B.; Dubos, T.; Gilbert, D. M.; Rivera-Mulia, J. C.; Qin, Z.

10.1101/394601 — bioinformatics — Posted on 2018-08-17

1249 Biomarker-based assessment of the muscle maintenance and energy status of anurans from an extremely seasonal semi-arid environment, the Brazillian Caatinga

Bonetti Madelaire, C.; Ribeiro Gomes, F.; Sokolova, I.

10.1101/394544 — physiology — Posted on 2018-08-17

1250 Soil bacterial biomass and diversity are affected by different furrow-ridge mulched management systems during potato continuous cropping

Zhang, W.; Qin, S.; Xu, X.; Zhang, J.; Liu, Y.

10.1101/394551 — microbiology — Posted on 2018-08-17

1251 Clonal analysis by tunable CRISPR-mediated excision

Gilles, A. F.; Schinko, J. B.; Schacht, M. I.; Enjolras, C.; Averof, M.

10.1101/394221 — genetics — Posted on 2018-08-17

1252 Establishing a cell-free Vibrio natriegens expression system

Wiegand, D. J.; Lee, H. H.; Ostrov, N.; Church, G. M.

10.1101/331645 — synthetic biology — Posted on 2018-08-17

1253 Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data

Finotello, F.; Mayer, C.; Plattner, C.; Laschober, G.; Rieder, D.; Hackl, H.; Krogsdam, A.; Posch, W.; Wilflingseder, D.; Sopper, S.; Jsselsteijn, M.; Johnsons, D.; Xu, Y.; Wang, Y.; Sanders, M. E.; Estrada, M. V.; Ericsson-Gonzalez, P.; Balko, J.; de Miranda, N. F.; Trajanoski, Z.

10.1101/223180 — bioinformatics — Posted on 2018-08-17

1254 Association of Prevotella enterotype with polysomnographic data in obstructive sleep apnea/hypopnea syndrome patients

Ko, C.-Y.; Fan, J.-M.; Hu, A.-K.; Huang, L.-M.; Su, H.-Z.; Yang, J.-H.; Zhang, H.-P.; Zeng, Y.-M.

10.1101/394064 — microbiology — Posted on 2018-08-17

1255 Supervised machine learning to decipher the complex associations between neuro-immune biomarkers and quality of life in schizophrenia

Kanchanatawan, B.; Maes, M.

10.1101/393942 — neuroscience — Posted on 2018-08-17

1256 Task complexity interacts with state-space uncertainty in the arbitration process between model-based and model-free reinforcement-learning at both behavioral and neural levels

Kim, D.; Park, G. Y.; O'Doherty, J. P.; Lee, S. W.

10.1101/393983 — neuroscience — Posted on 2018-08-17

1257 Nuclear TARBP2 drives oncogenic dysregulation of RNA splicing and decay

Fish, L.; Nguyen, H. C. B.; Zhang, S.; Hochman, M.; Dill, B. D.; Molina, H.; Najafabadi, H. S.; Alarcon, C.; Goodarzi, H.

10.1101/389213 — molecular biology — Posted on 2018-08-17

1258 Deciphering regulatory DNA sequences and noncoding genetic variants using neural network models of massively parallel reporter assays

Movva, R.; Greenside, P.; Shrikumar, A.; Kundaje, A.

10.1101/393926 — genomics — Posted on 2018-08-17

1259 Correlation between the aberrant human testicular germ-cell gene expression and disruption of spermatogenesis leading to male infertility

Baksi, A.; Jain, R.; Manjithaya, R.; S, V. S.; Kondaiah, P.; Dighe, R. R.

10.1101/394049 — genomics — Posted on 2018-08-17

1260 A feedback loop between miRNA-155, Programmed cell death 4 and Activation Protein-1 modulates the expression of miR-155 and tumorigenesis in tongue cancer

Zargar, S. A.; Singh, V. T.; Shyamsundar, V.; Vijayalakshmi, R.; Somasundaram, K.; Karunagaran, D.

10.1101/394130 — cancer biology — Posted on 2018-08-17

1261 Minor isozymes tailor yeast metabolism to carbon availability

Bradley, P. H.; Gibney, P. A.; Botstein, D.; Troyanskaya, O.; Rabinowitz, J.

10.1101/394056 — systems biology — Posted on 2018-08-17

1262 Adaptive evolution of feed-forward loops versus diamonds to filter out short spurious signals

Xiong, K.; Lancaster, A. K.; Siegal, M. L.; Masel, J.

10.1101/393884 — systems biology — Posted on 2018-08-17

1263 Carbapenemases on the move: it’s good to be on ICE

Botelho, J.; Roberts, A. P.; Leon-Sampedro, R.; Grosso, F.; Peixe, L.

10.1101/392894 — microbiology — Posted on 2018-08-17

1264 Transcriptomic responses of the marine cyanobacterium Prochlorococcus to viral lysis products

Fang, X.; Liu, Y.; Zhao, Y.; Chen, Y.; Liu, R.; Qin, Q.-L.; Li, G.; Zhang, Y.-Z.; Chan, W.; Hess, W.; Zeng, Q.

10.1101/394122 — microbiology — Posted on 2018-08-17

1265 Deep convolutional neural networks for accurate somatic variant calling

Sahraeian, S. M. E.; Liu, R.; Lau, B.; Mohiyuddin, M.; Lam, H. Y. K.

10.1101/393801 — genomics — Posted on 2018-08-17

1266 Structurally distinct endocytic pathways for B cell receptors in B lymphocytes

Davenport, T. M.; Dickey, A. M.; Ahn, R.; Roberts, A. D.; Sochacki, K. A.; Taraska, J. W.

10.1101/394015 — cell biology — Posted on 2018-08-17

1267 Balancing dynamic tradeoffs to drive cellular reprogramming

Babos, K. N.; Galloway, K. E.; Kisler, K. K.; Zitting, M.; Li, Y.; Quintino, B.; Chow, R. H.; Zlokovic, B. V.; Ichida, J. K.

10.1101/393934 — cell biology — Posted on 2018-08-17

1268 Optimized cross-linking mass spectrometry for in situ interaction proteomics

Ser, Z.; Cifani, P.; Kentsis, A.

10.1101/393892 — systems biology — Posted on 2018-08-17

1269 The representational dynamics of visual objects in rapid serial visual processing streams

Grootswagers, T.; Robinson, A. K.; Carlson, T. A.

10.1101/394148 — neuroscience — Posted on 2018-08-17

1270 Mechanism of Microbicidal Action of E-101 Solution, a Myeloperoxidase-Mediated Antimicrobial, and its Oxidative Products

Denys, G. A.; Devoe, N. C.; Gudis, P.; May, M.; Allen, R.; Stephens, J. T.

10.1101/394114 — microbiology — Posted on 2018-08-17

1271 A novel Versatile Peroxidase from Lentinus squarrosulus (MH172167)towards enhanced delignification and digestibility of crop residues

Ravichandran, A.; Rao, R. G.; Thammaiah, V.; gopinath, s. m.; Sridhar, M.

10.1101/394098 — microbiology — Posted on 2018-08-17

1272 Existing host range mutations constrain further emergence of RNA viruses

Zhao, L.; Seth Pasricha, M.; Stemate, D.; Crespo-Bellido, A.; Gagnon, J.; Duffy, S.

10.1101/394080 — microbiology — Posted on 2018-08-17

1273 Induction of the BIMS Splice Variant Sensitizes Proliferating NK Cells to IL-15 Withdrawal

Jacobs, B.; Pfefferle, A.; Clement, D.; Goodridge, J. P.; Saetersmoen, M. L.; Lorenz, S.; Wiiger, M. T.; Malmberg, K.-J.

10.1101/392985 — immunology — Posted on 2018-08-17

1274 Penton-dodecahedron of fowl adenovirus serotype 4 as a vaccine candidate for the control of related diseases

Tang, Q.; Dang, R.; Qiu, L.; Yang, Z.; Wang, X.

10.1101/394072 — immunology — Posted on 2018-08-17

1275 De novo genesis of retinal ganglion cells by targeted expression of KLF4 in vivo

Rocha-Martins, M.; de Toledo, B. C.; Santos-Franca, P. L.; Oliveira-Valenca, V. M.; Vieira e Vieira, C. H. H.; Matos-Rodrigues, G. E.; Linden, R.; Norden, C.; Martins, R. A. P.; Silveira, M. S.

10.1101/393967 — developmental biology — Posted on 2018-08-17

1276 Ultra-fast and accurate motif finding in large ChIP-seq datasets reveals transcription factor binding patterns

Li, Y.; Ni, P.; Zhang, S.; LI, G.; Su, Z.

10.1101/394007 — bioinformatics — Posted on 2018-08-17

1277 A retrospective evaluation of automated optimization of deep brain stimulation parameters

Vorwerk, J.; Brock, A. A.; Anderson, D. N.; Rolston, J. D.; Butson, C. R.

10.1101/393900 — bioengineering — Posted on 2018-08-17

1278 A Metagenomic Comparison of Tracheal Aspirate and Mini-Bronchial Alveolar Lavage for Assessment of Respiratory Microbiota

Kalantar, K.; Moazed, F.; Christenson, S.; Wilson, J.; Deiss, T.; Belzer, A.; Vessell, K.; Jauregui, A.; Boulourchi, S.; DeRisi, J. L.; Calfee, C.; Langelier, C.

10.1101/375360 — microbiology — Posted on 2018-08-17

1279 Cortex-wide neural interfacing via transparent polymer skulls

Ghanbari, L.; Carter, R. E.; Rynes, M. L.; Dominguez, J.; Chen, G.; Naik, A.; Hu, J.; Sagar, M. A. K.; Haltom, L.; Mossazghi, N.; Gray, M. M.; West, S. L.; Eliceiri, K. W.; Ebner, T. J.; Kodandaramaiah, S. B.

10.1101/387142 — neuroscience — Posted on 2018-08-17

1280 Novel small molecule agonists of an Aedes aegypti neuropeptide Y receptor block mosquito biting behavior

Duvall, L. B.; Ramos-Espiritu, L.; Barsoum, K. E.; Glickman, J. F.; Vosshall, L. B.

10.1101/393793 — neuroscience — Posted on 2018-08-16

1281 Hierarchical Bayesian inference for concurrent model fitting and comparison for group studies

Piray, P.; Dezfouli, A.; Heskes, T.; Frank, M. J.; Daw, N. D.

10.1101/393561 — neuroscience — Posted on 2018-08-16

1282 Integrative Transcription Start Site Analysis and Physiological Phenotyping Reveal Torpor-Specific Expressions in Mouse Skeletal Muscle

Sunagawa, G. A.; Deviatiiarov, R.; Ishikawa, K.; Gazizova, G.; Gusev, O.; Takahashi, M.

10.1101/374975 — physiology — Posted on 2018-08-16

1283 Multiparametric Signature of Glioblastoma Differentiation Revealed by Imaging of Cellular Epigenetic Landscapes

Farhy, C.; Hariharan, S.; Ylanko, J.; van Woudenberg, L.; Cimadamore, F.; Ugarte, F.; Forsberg, C.; Huang, C.-T.; Andrews, D.; Terskikh, A.

10.1101/348888 — cancer biology — Posted on 2018-08-16

1284 Dual RNA-seq reveals large-scale non-conserved genotype x genotype specific genetic reprograming and molecular crosstalk in the mycorrhizal symbiosis

Sanders, I. R.; Mateus, I. D.; Masclaux, F. G.; Aletti, C.; Rojas, E. C.; Savary, R.; Dupuis, C.

10.1101/393637 — plant biology — Posted on 2018-08-16

1285 A Reassessment of the Taxonomic Position of Mesosaurs Based on Two Data Matrices

Laurin, M.; Pineiro, G.

10.1101/391813 — paleontology — Posted on 2018-08-16

1286 Proprioceptive Deficits in Inactive Older Adults are not Reflected in Discrete Reaching Performance

Kitchen, N. M.; Miall, R. C.

10.1101/393785 — neuroscience — Posted on 2018-08-16

1287 Transcriptome and Comparative Genomics analyses reveal new functional insights on key determinants of pathogenesis and interbacterial competition in Pectobacterium and Dickeya spp

Bellieny-Rabelo, D.; Kipngetich Tanui, C.; Miguel, N.; Kwenda, S.; Yufetar Shyntum, D.; Novungayo Moleleki, L.

10.1101/391854 — genomics — Posted on 2018-08-16

1288 Unified single-cell analysis of testis gene regulation and pathology in 5 mouse strains

Jung, M.; Wells, D.; Rusch, J.; Ahmed, S.; Marchini, J.; Myers, S.; Conrad, D.

10.1101/393769 — genomics — Posted on 2018-08-16

1289 When rarity has costs: coexistence under positive frequency-dependence and environmental stochasticity

Schreiber, S.; Yamamichi, M.; Strauss, S.

10.1101/161919 — ecology — Posted on 2018-08-16

1290 Cooperativity and Avidity in Membrane Binding by C2AB Tandem Domains of Synaptotagmins 1 and 7

Tran, H. T.; Anderson, L. H.; Knight, J. D.

10.1101/393702 — biophysics — Posted on 2018-08-16

1291 sierra-local: A lightweight standalone application for secure HIV-1 drug resistance prediction

Ho, J. C.; Ng, G. T.; Renaud, M.; Poon, A. F.

10.1101/393207 — bioinformatics — Posted on 2018-08-16

1292 The identification of DNA binding regions of the σ54 factor using artificial neural network

Ferreira, L. M.; Raittz, R. T.; Marchaukoski, J. N.; Weiss, V. A.; Santos-Wiess, I. C. R.; Costa, P. A. B.; Voyceik, R.; Rigo, L. U.

10.1101/393736 — bioinformatics — Posted on 2018-08-16

1293 K-mer based classifiers extract functionally relevant features to support accurate Peroxiredoxin subgroup distinction

Xiao, J.; Turkett, W.

10.1101/387787 — bioinformatics — Posted on 2018-08-16

1294 Strong selection of a few dominant CD8 clones in a TLR7-dependent autoimmune mouse model

Morawski, P.; Bolland, S.

10.1101/393819 — immunology — Posted on 2018-08-16

1295 Adhesion to nanofibers drives cell membrane remodeling through 1D wetting

Charles-Orszag, A.; Tsai, F.-C.; Bonazzi, D.; Manriquez, V.; Sachse, M.; Mallet, A.; Salles, A.; Melican, K.; Staneva, R.; Bertin, A.; Millien, C.; Goussard, S.; Lafaye, P.; Shorte, S.; Piel, M.; Krijnse-Locker, J.; Brochard-Wyart, F.; Bassereau, P.; Dumenil, G.

10.1101/393744 — cell biology — Posted on 2018-08-16

1296 The core genome m5C methyltransferase JHP1050 (M.Hpy99III) plays an important role in orchestrating gene expression in Helicobacter pylori

Estibariz, I.; Overmann, A.; Ailloud, F.; Krebes, J.; Josenhans, C.; Suerbaum, S.

10.1101/393710 — microbiology — Posted on 2018-08-16

1297 Mycobacteria-specific CD4+IFN-γ+ cell expresses naïve-surface markers and confers superior protection against tuberculosis infection compared to central and effector memory CD4+ T cell subsets

Chatterjee, S.; Yuan, J.; Tenant, J.; Pacatte, T.; Eickhoff, C.; Blazevic, A.; Hoft, D.

10.1101/384784 — immunology — Posted on 2018-08-16

1298 Morphogenesis of neurons and glia within an epithelium

Low, I. I. C.; Williams, C. R.; Chong, M. K.; McLachlan, I. G.; Wierbowski, B. M.; Kolotuev, I.; Heiman, M. G.

10.1101/393850 — developmental biology — Posted on 2018-08-16

1299 Modelling palaeoecological time series using generalized additive models

Simpson, G. L.

10.1101/322248 — ecology — Posted on 2018-08-16

1300 A quantitative genetics model for the dynamics of phenotypic (co)variances under limited dispersal, with an application to the coevolution of socially synergistic traits

Mullon, C.; Lehmann, L.

10.1101/393538 — evolutionary biology — Posted on 2018-08-16

1301 Multimodal integration and vividness in the angular gyrus during episodic encoding and retrieval

Tibon, R.; Fuhrmann, D.; Levy, D. A.; Simons, J.; Henson, R. N.

10.1101/393553 — neuroscience — Posted on 2018-08-16

1302 Protection against repeated vaginal SHIV challenges by a combination of VRC01 and an anti-α4β7 antibody

Calenda, G.; Frank, I.; Arrode-Bruses, G.; Pegu, A.; Wang, K.; Arthos, J.; Cicala, C.; Grasperge, B.; Blanchard, J. L.; Maldonado, S.; Roberts, K.; Gettie, A.; Fauci, A. S.; Mascola, J. R.; Martinelli, E.

10.1101/365551 — immunology — Posted on 2018-08-16

1303 scMerge: Integration of multiple single-cell transcriptomics datasets leveraging stable expression and pseudo-replication

Lin, Y.; Ghazanfar, S.; Wang, K.; Gagnon-Bartsch, J. A.; Lo, K. K.; Su, X.; Han, Z.-G.; Ormerod, J. T.; Speed, T. P.; Yang, P.; Yang, J. Y. H.

10.1101/393280 — bioinformatics — Posted on 2018-08-16

1304 Tendon Structure Quantified using Ultrasound Imaging Differs Based on Location and Training Type

Hagan, K. L.; Hullfish, T. J.; Casey, E.; Baxter, J. R.

10.1101/393520 — bioengineering — Posted on 2018-08-16

1305 Sleep timing in industrial and pre-industrial societies syncs to the light/dark cycle

Martin-Olalla, J. M.

10.1101/392035 — physiology — Posted on 2018-08-16

1306 The ANTs Longitudinal Cortical Thickness Pipeline

Tustison, N. J.; Holbrook, A. J.; Avants, B. B.; Roberts, J. M.; Cook, P. A.; Reagh, Z. M.; Duda, J. T.; Stone, J. R.; Gillen, D. L.; Yassa, M. A.

10.1101/170209 — neuroscience — Posted on 2018-08-16

1307 AnatomyNet: Deep 3D Squeeze-and-excitation U-Nets for fast and fully automated whole-volume anatomical segmentation

Zhu, W.; Huang, Y.; Tang, H.; Qian, Z.; Du, N.; Fan, W.; Xie, X.

10.1101/392969 — bioengineering — Posted on 2018-08-16

1308 Predator detection through active photolocation in a diurnal fish

Santon, M.; Bitton, P.-P.; Dehm, J.; Fritsch, R.; Harant, U. K.; Anthes, N.; Michiels, N. K.

10.1101/324202 — zoology — Posted on 2018-08-16

1309 Functional dissection of the ARGONAUTE7 promoter

Hoyer, J. S.; Pruneda-Paz, J. L.; Breton, G.; Hassert, M. A.; Holcomb, E. E.; Fowler, H.; Bauer, K. M.; Mreen, J.; Kay, S. A.; Carrington, J. C.

10.1101/392910 — plant biology — Posted on 2018-08-16

1310 Reducing tau ameliorates behavioural and transcriptional deficits in a novel model of Alzheimer’s disease

Pickett, E. K.; Herrmann, A. G.; McQueen, J.; Abt, K.; Dando, O.; Tulloch, J.; Jain, P.; Dunnett, S.; Sohrabi, S.; Fjeldstad, M.; Calkin, W.; Murison, L.; Jackson, R. J.; Tzioras, M.; Stevenson, A.; D'Orange, M.; Hooley, M.; Davies, C.; Oren, I.; Rose, J.; McKenzie, C.-A.; Allison, E.; Smith, C.; Hardt, O.; Henstridge, C. M.; Hardingham, G.; Spires-Jones, T.

10.1101/393405 — neuroscience — Posted on 2018-08-16

1311 Sequential replay of non-spatial task states in the human hippocampus

Schuck, N. W.; Niv, Y.

10.1101/315978 — neuroscience — Posted on 2018-08-16

1312 Streptococcal Lancefield polysaccharides are critical cell wall determinants for human group IIA secreted phospholipase A2 to exert its bactericidal effects

van Hensbergen, V. P.; Movert, E.; de Maat, V.; Luechtenborg, C.; Le Breton, Y.; Lambeau, G.; Payre, C.; Henningham, A.; Nizet, V.; Van Strijp, J. A. G.; Bruegger, B.; Carlsson, F.; McIver, K. S.; van Sorge, N. M.

10.1101/269779 — microbiology — Posted on 2018-08-16

1313 A genus definition for Bacteria and Archaea based on genome relatedness and taxonomic affiliation.

Barco, R. A.; Garrity, G. M.; Scott, J. J.; Amend, J. P.; Nealson, K. H.; Emerson, D.

10.1101/392480 — microbiology — Posted on 2018-08-16

1314 Effective principal components analysis of SNP data

Gauch, H. G.; Qian, S.; Piepho, H.-P.; Zhou, L.; Chen, R.

10.1101/393611 — genomics — Posted on 2018-08-16

1315 Cbs overdosage is necessary and sufficient to induce cognitive phenotypes in mouse models of Down syndrome and interacts genetically with Dyrk1a

Marechal, D.; Brault, V.; Leon, A.; Martin, D.; Lopes Pereira, P.; Loaec, N.; Birling, M.-C.; Friocourt, G.; Blondel, M.; Herault, Y.

10.1101/393579 — genetics — Posted on 2018-08-16

1316 Ending AIDS: trends in the incidence of HIV in eastern and southern Africa

Williams, B. G.; Granich, R.

10.1101/383372 — epidemiology — Posted on 2018-08-16

1317 NGseqBasic - a single-command UNIX tool for ATAC-seq, DNaseI-seq, Cut-and-Run, and ChIP-seq data mapping, high-resolution visualisation, and quality control

Telenius, J. M.; The WIGWAM Consortium, ; Hughes, J. R.

10.1101/393413 — bioinformatics — Posted on 2018-08-16

1318 FastqCleaner: an interactive Bioconductor application for quality-control, filtering and trimming of FASTQ files

Roser, L. G.; Aguero, F.; Sanchez, D.

10.1101/393140 — bioinformatics — Posted on 2018-08-16

1319 Improving the classification of neuropsychiatric conditions using gene ontology terms as features

Quinn, T. P.; Lee, S. C.; Venkatesh, S.; Nguyen, T.

10.1101/393082 — bioinformatics — Posted on 2018-08-16

1320 Discovery of tandem and interspersed segmental duplications using high throughput sequencing

Soylev, A.; Le, T.; Amini, H.; Alkan, C.; Hormozdiari, F.

10.1101/393694 — bioinformatics — Posted on 2018-08-16

1321 Prediction and analysis of skin cancer progression using genomics profiles of patients

Bhalla, S.; Kaur, H.; Dhall, A.; Raghava, G. P. S.

10.1101/393454 — bioinformatics — Posted on 2018-08-16

1322 The saturation gap: a simple transformation of oxygen saturation using virtual shunt

Zhou, G.; Karlen, W.; Brant, R.; Wiens, M.; Ansermino, M.

10.1101/391292 — bioengineering — Posted on 2018-08-16

1323 Limits to anatomical accuracy of diffusion tractography using modern approaches

Schilling, K. G.; Nath, V.; Hansen, C.; Parvathaneni, P.; Blaber, J.; Gao, Y.; Neher, P.; Aydogan, D. B.; Shi, Y.; Ocampo-Pineda, M.; Schiavi, S.; Daducci, A.; Girard, G.; Barakovic, M.; Rafael-Patino, J.; Romascano, D.; Rensonnet, G.; Pizzolato, M.; Bates, A.; Fischi, E.; Thiran, J.-P.; Canales-Rodriguez, E. J.; Huang, C.; Zhu, H.; Zhong, L.; Cabeen, R.; Toga, A. W.; Rheault, F.; Theaud, G.; Houde, J.-C.; Sidhu, J.; Chamberland, M.; Westin, C.-F.; Dyrby, T. B.; Verma, R.; Rathi, Y.; Irfanoglu, M. O.; Thomas, C.; Pierpaoli, C.; Descoteaux, M.; Anderson, A. W.; Landman, B. A.

10.1101/392571 — neuroscience — Posted on 2018-08-16

1324 Regional Striatal Cholinergic Involvement in Human Behavioural Flexibility

Bell, T.; Lindner, M.; Langdon, A.; Mullins, P. G.; Christakou, A.

10.1101/392233 — neuroscience — Posted on 2018-08-16

1325 Intact mast cell content during mild head injury is required for the development of latent pain sensitization - implications for mechanisms underlying posttraumatic headache

Bree, D.; Levy, D.

10.1101/392928 — neuroscience — Posted on 2018-08-16

1326 CCCP experimental evolution of Escherichia coli K-12 selects for mutations that increase EmrA activity or that downregulate other PMF-driven drug efflux pumps

Griffith, J. M.; Basting, P. J.; Bischof, K. M.; Wrona, E. P.; Kunka, K. S.; Tancredi, A. C.; Moore, J. P.; Hyman, M. R. L.; Slonczewski, J. L.

10.1101/392977 — microbiology — Posted on 2018-08-16

1327 Bclaf1 critically regulates the type I interferon response and is degraded by alphaherpesvirus US3

Qin, C.; Zhang, R.; Lang, Y.; Shao, A.-w.; Xu, A.; Feng, W.; Han, J.; Wang, M.; He, W.; Yu, C.; Tang, J.

10.1101/392555 — immunology — Posted on 2018-08-16

1328 The perils of intralocus recombination for inferences of molecular convergence

Mendes, F. K.; Livera, A.; Hahn, M. W.

10.1101/393124 — evolutionary biology — Posted on 2018-08-16

1329 Global climate changes will lead to regionally divergent trajectories for ectomycorrhizal communities in North American Pinaceae forests

Steidinger, B.; Bhatnagar, J.; Vilgalys, R.; Taylor, J.; Bruns, T.; Peay, K. G.

10.1101/393009 — ecology — Posted on 2018-08-16

1330 The SHAPE of logistic growth shows that timing does matter

Dench, J.

10.1101/392944 — bioinformatics — Posted on 2018-08-16

1331 Hyperparameter-free optimizer of stochastic gradient descent that incorporates unit correction and moment estimation

Yamada, K. D.

10.1101/348557 — bioinformatics — Posted on 2018-08-16

1332 An algorithm for automated, noninvasive detection of cortical spreading depolarizations based on EEG simulations

Chamanzar, A.; George, S.; Venkatesh, P.; Chamanzar, M.; Shutter, L.; Elmer, J.; Grover, P.

10.1101/393058 — bioengineering — Posted on 2018-08-16

1333 Reconstitution of mammalian Cleavage Factor II involved in 3’ processing of mRNA precursors

Schaefer, P.; Tueting, C.; Schoenemann, L.; Kuehn, U.; Treiber, T.; Treiber, N.; Ihling, C.; Graber, A.; Keller, W.; Meister, G.; Sinz, A.; Wahle, E.

10.1101/366336 — biochemistry — Posted on 2018-08-16

1334 Stochasticity in multi-phosphorylation and quasi steady state approximation in stochastic simulation

Barik, D.; Das, S.

10.1101/392951 — systems biology — Posted on 2018-08-16

1335 Decoding semantic predictions from EEG prior to word onset

Heikel, E.; Sassenhagen, J.; Fiebach, C. J.

10.1101/393066 — neuroscience — Posted on 2018-08-16

1336 A new schizophrenia model: immune activation is associated with induction of thetryptophan catabolite pathway and increased eotaxin levels which together determinememory impairments and schizophrenia symptom dimensions.

Sirivichayakul, S.; Kanchanatawan, B.; Thika, S.; Carvalho, A.; Maes, M.

10.1101/393173 — neuroscience — Posted on 2018-08-16

1337 In vivo detection of optically-evoked opioid peptide release

Al-Hasani, R.; Wong, J.-M. T.; Mabrouk, O. S.; McCall, J. G.; Schmitz, G. P.; Porter-Stransky, K. A.; Aragona, B. J.; Kennedy, R. T.; Bruchas, M. R.

10.1101/393603 — neuroscience — Posted on 2018-08-16

1338 Signalling pathways drive heterogeneity of ground state pluripotency

McEwen, K. R.; Linnett, S.; Leitch, H. G.; Srivastava, P.; Al-Zouabi, L.; Huang, T.-C.; Rotival, M.; Sardini, A.; Chan, T. E.; Filippi, S.; Stumpf, M.; Petretto, E.; Hajkova, P.

10.1101/373373 — molecular biology — Posted on 2018-08-16

1339 Atlas of Neuromuscular Organization in the Ctenophore, Pleurobrachia bachei (A. Agassiz, 1860)

Moroz, L. L.; Norekian, T. P.

10.1101/385435 — evolutionary biology — Posted on 2018-08-16

1340 To block or not to block: the adaptive manipulation of plague transmission

Gandon, S.; Heitzmann, L.; Sebbane, F.

10.1101/392514 — evolutionary biology — Posted on 2018-08-16

1341 A novel enhancer RNA, Hmrhl, positively regulates its host gene, phkb, in Chronic Myelogenous Leukemia

Fatima, R.; Choudhury, S. R.; Rajendran, D. T.; Bhaduri, U.; Rao, S. M. R.

10.1101/378984 — cancer biology — Posted on 2018-08-16

1342 NucBreak: Location of structural errors in a genome assembly by using paired-end Illumina reads

Khelik, K.; Sandve, G. K.; Nederbragt, A. J.; Rognes, T.

10.1101/393488 — bioinformatics — Posted on 2018-08-16

1343 BAMM-SC: A Bayesian mixture model for clustering droplet-based single cell transcriptomic data from population studies

Sun, Z.; Chen, L.; Xin, H.; Huang, Q.; Cillo, A.; Tabib, T.; Ding, Y.; Kolls, J.; Bruno, T.; Lafyatis, R.; Vignali, D.; Chen, K.; Hu, M.; Chen, W.

10.1101/392662 — bioinformatics — Posted on 2018-08-16

1344 Hierarchical Bayesian inference for concurrent model fitting and comparison for group studies

Piray, P.; Dezfouli, A.; Heskes, T.; Frank, M. J.; Daw, N.

10.1101/393561 — neuroscience — Posted on 2018-08-16

1345 Estimation of narrowband amplitude and phase from electrophysiology signals for phase-amplitude coupling studies: a comparison of methods

Soto, J. L.; Prado, F. V.; Combrisson, E.; Jerbi, K.

10.1101/392886 — neuroscience — Posted on 2018-08-16

1346 Appearance of synthetic vector-associated antibiotic resistance genes in next-generation sequences

Taiaroa, G.; Cook, G.; Williamson, D.

10.1101/392225 — microbiology — Posted on 2018-08-16

1347 A genus definition for Bacteria and Archaea based on genome relatedness and taxonomic affiliation.

Barco, R. A.; Garrity, G. M.; Scott, J. J.; Amend, J.; Nealson, K. H.; Emerson, D.

10.1101/392480 — microbiology — Posted on 2018-08-16

1348 Positive selection in Europeans and East-Asians at the ABCA12 gene

Sirica, R.; Buonaiuto, M.; Petrella, V.; Sticco, L.; Tramontano, D.; Antonini, D.; Missero, C.; Guardiola, O.; Andolfi, G.; Kumar, H.; Ayub, Q.; Xue, Y.; Tyler-Smith, C.; Salvemini, M.; D'Angelo, G.; Colonna, V.

10.1101/392811 — genomics — Posted on 2018-08-16

1349 Estimating parameters from multiple time series of population dynamics using Bayesian inference

Rosenbaum, B.; Raatz, M.; Weithoff, G.; Fussmann, G. F.; Gaedke, U.

10.1101/392449 — ecology — Posted on 2018-08-16

1350 Keystone mutualists can facilitate transition between alternative ecosystem states in the soil

Duhamel, M.; Wan, J.; Bogar, L. M.; Segnitz, R. M.; Duncritts, N. C.; Peay, K.

10.1101/392993 — ecology — Posted on 2018-08-16

1351 Using machine learning to associate bacterial taxa with functional groups through flow cytometry, 16S rRNA gene sequencing, and productivity data

Rubbens, P.; Schmidt, M. L.; Props, R.; Biddanda, B. A.; Boon, N.; Waegeman, W.; Denef, V. J.

10.1101/392852 — ecology — Posted on 2018-08-16

1352 Risk factors contributing to Bacteraemia at a Tertiary Cancer Center in South Asia

Lenaduwe, S. L. A.; Sandunika, A.; Widanagamage, R.; Dias, P.; Gunesekera, S.

10.1101/386193 — cancer biology — Posted on 2018-08-16

1353 Regional Striatal Cholinergic Involvement in Human Behavioural Flexibility

Bell, T.; Lindner, M.; Langdon, A.; Mullins, P. G.; Christakou, A.

10.1101/392233 — neuroscience — Posted on 2018-08-16

1354 Cell Diameter in Bacillus subtilis is Determined by the Opposing Actions of Two Distinct Cell Wall Synthetic Systems

Dion, M.; Kapoor, M.; Sun, Y.; Wilson, S.; Ryan, J.; Vigouroux, A.; Bikard, D.; van Teeffelen, S.; Oldenbourg, R.; Garner, E. C.

10.1101/392837 — microbiology — Posted on 2018-08-16

1355 Neuropsychiatric Phenotypes in 3q29 Deletion Syndrome

Pollak, R. M.; Murphy, M. M.; Epstein, M. P.; Zwick, M. E.; Klaiman, C.; Saulnier, C. A.; Mulle, J. G.

10.1101/386243 — genetics — Posted on 2018-08-16

1356 Quantifying biosynthetic network robustness across the human oral microbiome

Bernstein, D.; Dewhirst, F.; Segre, D.

10.1101/392621 — systems biology — Posted on 2018-08-16

1357 Identification of candidate genes underlying nodulation-specific phenotypes in Medicago truncatula through integration of genome-wide association studies and co-expression networks

Michno, J.-M.; Burghardt, L. T.; Liu, J.; Jeffers, J. R.; Tiffin, P.; Stupar, R. M.; Myers, C. L.

10.1101/392779 — systems biology — Posted on 2018-08-16

1358 Whole-genome sequencing of three native cattle breeds originating from the northernmost cattle farming regions

Weldenegodguad, M.; Popov, R.; Pokharel, K.; Ammosov, I.; Yao, M.; Ivanova, Z.; Kantanen, J.

10.1101/390369 — genomics — Posted on 2018-08-16

1359 Phenotypic Effects of Somatic Mutations Accumulating during Vegetative Growth

Cruzan, M.; Streisfeld, M.; Schwoch, J.

10.1101/392175 — evolutionary biology — Posted on 2018-08-16

1360 Enlarged and highly repetitive plastome of Lagarostrobos and plastid phylogenomics of Podocarpaceae

Sudianto, E.; Wu, C.-S.; Leonhard, L.; Martin, W. F.; Chaw, S.-M.

10.1101/392357 — evolutionary biology — Posted on 2018-08-16

1361 Global cooling & the rise of modern grasslands: Revealing cause & effect of environmental change on insect diversification dynamics

Davis, K. E.; Bakewell, A. T.; Hill, J.; Song, H.; Mayhew, P.

10.1101/392712 — ecology — Posted on 2018-08-16

1362 Unbiased Age-Appropriate Structural Brain Atlases for Chinese Pediatrics

Zhao, T.; Liao, X.; Fonov, V.; Men, W.; Wang, Y.; Qin, S.; Tan, S.; Gao, J.; Evans, A.; Tao, S.; Dong, Q.; He, Y.

10.1101/385211 — neuroscience — Posted on 2018-08-16

1363 Droplet rather than Aerosol Mediated Dispersion is the Primary Mechanism of Bacterial transmission from Contaminated Hand Washing Sink Traps

Kotay, S. M.; Donlan, R. M.; Ganim, C.; Barry, K. E.; Christensen, B. E.; Mathers, A. J.

10.1101/392431 — microbiology — Posted on 2018-08-16

1364 SonHi-C: a set of non-procedural approaches for predicting 3D genome organization from Hi-C data

MacKay, K.; Carlsson, M.; Kusalik, A.

10.1101/392407 — bioinformatics — Posted on 2018-08-16

1365 Hidden Markov Models Lead to Higher Resolution Maps of Mutation Signature Activity in Cancer

Huang, X.; Sason, I.; Wojtowicz, D.; Kim, Y.-A.; Leiserson, M.; Przytycka, T. M.; Sharan, R.

10.1101/392639 — bioinformatics — Posted on 2018-08-16

1366 Demography and behavior of polygyne nests of the supercolonial Cataglyphis niger: Does kinship matter?

Reiner Brodetzki, T.; Feinerman, O.; Brodetzki, G.; Hefetz, A.

10.1101/392522 — animal behavior and cognition — Posted on 2018-08-16

1367 Real-time experimental control using network-based parallel processing

Kim, B.; Kenchappa, S. C.; Sunkara, A.; Chang, T.-Y.; Thompson, L.; Doudlah, R.; Rosenberg, A.

10.1101/392654 — neuroscience — Posted on 2018-08-16

1368 Chemogenetic restoration of autonomous subthalamic nucleus activity ameliorates Parkinsonian motor dysfunction

McIver, E. L.; Chu, H.-Y.; Atherton, J. F.; Cosgrove, K. E.; Kondapalli, J.; Wokosin, D.; Surmeier, D. J.; Bevan, M. D.

10.1101/385443 — neuroscience — Posted on 2018-08-16

1369 Multimodal gradients across mouse cortex

Fulcher, B. D.; Murray, J. D.; Zerbi, V.; Wang, X.-J.

10.1101/393215 — neuroscience — Posted on 2018-08-16

1370 The relative contribution of color and material in object selection

Radonjic, A.; Cottaris, N. P.; Brainard, D.

10.1101/393470 — neuroscience — Posted on 2018-08-16

1371 Kinematics of wings from Caudipteryx to modern birds

Zhao, J.-S.; Saffar Talori, Y.; O'Connor, J. K.; Yaser Saffar Talori, Jing-Shan Zhao, Jingmai Kathleen O'Connor,

10.1101/393686 — paleontology — Posted on 2018-08-16

1372 Mitochondrial genome annotation and phylogenetic placement of Oreochromis andersonii and O. macrochir among the cichlids of southern Africa

Bbole, I.; Zhao, J.-L.; Tang, S.-J.; Katongo, C.

10.1101/393660 — genomics — Posted on 2018-08-16

1373 Determinants of Minimum Acceptable Diet among 6-23 Months Age Children in Ethiopia: A Multilevel Analysis of The Ethiopian Demographic Health Survey

Adhena, B. M.; Yemane, D. T.; Bekele, A. B.; Tasew, A. A.

10.1101/393678 — developmental biology — Posted on 2018-08-16

1374 Sample Preparation by Easy Extraction and Digestion (SPEED) - A Universal, Rapid, and Detergent-free Protocol for Proteomics based on Acid Extraction

Doellinger, J.; Schneider, A.; Hoeller, M.; Lasch, P.

10.1101/393249 — systems biology — Posted on 2018-08-16

1375 Structures of the substrate-engaged 26S proteasome reveal the mechanisms for ATP hydrolysis-driven translocation

de la Pena, A. H.; Goodall, E. A.; Gates, S. N.; Lander, G. C.; Martin, A.

10.1101/393223 — molecular biology — Posted on 2018-08-16

1376 Gene silencing by double-stranded RNA from C. elegans neurons reveals functional mosaicism of RNA interference

Ravikumar, S.; Devanapally, S.; Jose, A. M.

10.1101/393074 — genetics — Posted on 2018-08-16

1377 eTumorRisk, an algorithm predicts cancer risk based on comutated gene networks in an individual’s germline genome

Zou, J.; Wang, E.

10.1101/393090 — bioinformatics — Posted on 2018-08-16

1378 Molecular flexibility of DNA as a major determinant of RAD51 recruitment

Paoletti, F.; El-Sagheer, A.; Allard, J.; Brown, T.; Dushek, O.; Esashi, F.

10.1101/392795 — biochemistry — Posted on 2018-08-16

1379 Optimized Cas9 expression systems for highly efficient Arabidopsis genome editing facilitate isolation of complex alleles in a single generation

Ordon, J.; Bressan, M.; Kretschmer, C.; Dall'Osto, L.; Marillonnet, S.; Bassi, R.; Stuttmann, J.

10.1101/393439 — plant biology — Posted on 2018-08-16

1380 Dexi disruption depletes gut microbial metabolites and accelerates autoimmune diabetes

Davison, L. J.; Wallace, M. D.; Preece, C.; Hughes, K.; Todd, J. A.; Davies, B.; O'Callaghan, C. A.

10.1101/393421 — genetics — Posted on 2018-08-16

1381 Saccharomyces cerevisiae displays a stable transcription start site landscape in multiple conditions

Boerlin, C. S.; Cvetesic, N.; Holland, P.; Bergenholm, D.; Siewers, V.; Lenhard, B.; Nielsen, J.

10.1101/393447 — systems biology — Posted on 2018-08-16

1382 Regulation by HSP70/90 in the different tissues and testis development of male cattle (Cattle-yak and Yak)

Liu, P.; Yu, S.; Cui, Y.; He, J.; Zhang, Q.; Liu, J.; Song, L.; Xu, Y.; Wang, T.; Zou, S.; Li, H.

10.1101/393371 — biochemistry — Posted on 2018-08-16

1383 Mapping molecular datasets back to the brain regions they are extracted from: Remembering the native countries of hypothalamic expatriates and refugees

Khan, A. M.; Grant, A. H.; Martinez, A.; Burns, G. A.; Thatcher, B. S.; Anekonda, V. T.; Thompson, B. W.; Roberts, Z. S.; Moralejo, D. H.; Blevins, J. E.

10.1101/307652 — neuroscience — Posted on 2018-08-16

1384 Pathways to Consumers Minds: Using Machine Learning and Multiple EEG Metrics to Increase Preference Prediction Above and Beyond Traditional Measurements

Hakim, A.; Klorfeld, S.; Sela, T.; Friedman, D.; Shabat-Simon, M.; Levy, D. J.

10.1101/317073 — neuroscience — Posted on 2018-08-16

1385 Bounded Rationality in C. elegans

Cohen, D.; Volovich, M.; Zeevi, Y.; Elbaum, L.; Louie, K.; Levy, D. J.; Rechavi, O.

10.1101/257535 — neuroscience — Posted on 2018-08-16

1386 Evaluating metabarcoding to analyse diet composition of species foraging in anthropogenic landscapes using Ion Torrent and Illumina sequencing

Forin-Wiart, M.-A.; Poulle, M.-L.; Piry, S.; Cosson, J.-F.; Larose, C.; Galan, M.

10.1101/295758 — molecular biology — Posted on 2018-08-16

1387 A Bacterial Expression Vector Archive (BEVA) forflexible modular assembly of Golden Gate-compatible vectors

Geddes, B. B.; Mendoza-Suarez, M.; Poole, P.

10.1101/392423 — microbiology — Posted on 2018-08-16

1388 Molecular Simulations of ion effects on the Thermodynamics of RNA Folding

Thirumalai, D.; Denesyuk, N. A.

10.1101/364935 — biophysics — Posted on 2018-08-16

1389 Bayes-Like Integration of a New Sensory Skill with Vision

Negen, J.; Wen, L.; Thaler, L.; Nardini, M.

10.1101/232579 — animal behavior and cognition — Posted on 2018-08-16

1390 Generation of Highly Diverse Peptide Library by Linear-double-stranded DNA Based AND Logic Computation in Mammalian Cells

Li, S.; Su, W.; Zhang, C.

10.1101/392498 — bioengineering — Posted on 2018-08-16

1391 Breathing coordinates limbic network dynamics underlying memory consolidation

Karalis, N.; Sirota, A.

10.1101/392530 — neuroscience — Posted on 2018-08-16

1392 Identification negative BOLD responses using windkessel models

Valdes-Hernandez, P. A.; Bernal, B.; Moshkforoush, A.; Dunoyer, C.; Ming Khoo, H.; Bosch-Bayard, J.; von Ellenrieder, N.; Gotman, J.; Riera, J. J.

10.1101/392290 — neuroscience — Posted on 2018-08-16

1393 Dissecting splicing decisions and cell-to-cell variability with designed sequence libraries

Mikl, M.; Hamburg, A.; Pilpel, Y.; Segal, E.

10.1101/392605 — genomics — Posted on 2018-08-16

1394 Effective Machine-Learning Assembly For Next-Generation Sequencing With Very Low Coverage

Ranjard, L.; Wong, T. K.; Rodrigo, A. G.

10.1101/393116 — bioinformatics — Posted on 2018-08-16

1395 Putative pore-forming subunits of the mechano-electrical transduction channel, Tmc1/2b, require Tmie to localize to the site of mechanotransduction in zebrafish sensory hair cells

Pacentine, I.; Nicolson, T.

10.1101/393330 — neuroscience — Posted on 2018-08-16

1396 Myocardial Notch-Rbpj deletion does not affect heart development or function

Salguero-Jimenez, A.; Grego-Bessa, J.; D'Amato, G.; Jimenez-Borreguero, L. J.; de la Pompa, J. L.

10.1101/393348 — developmental biology — Posted on 2018-08-16

1397 Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion

Liu, Y. J.; Janssens, G. E.; Kamble, R.; Gao, A. W.; Jongejan, A.; Weeghel, M. v.; MacInnes, A. W.; Houtkooper, R. H.

10.1101/393314 — systems biology — Posted on 2018-08-16

1398 Petite Integration Factor 1 (PIF1) helicase deficiency increases weight gain in Western diet-fed female mice without increased inflammatory markers or decreased glucose clearance

Kaufman, B. A.; Belmonte, F.; Dedousis, N.; Sipula, I.; Desai, N.; Singhi, A.; chu, y.; Zhang, Y.; Bannwarth, S.; Paquis-Flucklinger, V.; Harrington, L.; O'Doherty, R. M.; Jurczak, M. J.

10.1101/393355 — physiology — Posted on 2018-08-16

1399 No evidence for transvection in vivo by a superenhancer:promoter pair integrated into identical open chromatin at the Rosa26 locus

Tanimoto, K.; Matsuzaki, H.; Okamura, E.; Ushiki, A.; Fukamizu, A.; Engel, J. D.

10.1101/393363 — genomics — Posted on 2018-08-16

1400 Dual role of Bnl/Fgf signaling in proliferation and endoreplication of Drosophila trachealadult progenitor cells

Franch-Marro, X.; de miguel, C.; Cruz, J.; Martin, D.

10.1101/393306 — developmental biology — Posted on 2018-08-16

1401 Excess of rare missense variants in hearing loss genes in sporadic Meniere disease

Gallego-Martinez, A.; Requena, T.; Roman-Naranjo, P.; Lopez-Escamez, J. A.

10.1101/393322 — genomics — Posted on 2018-08-16

1402 Novel allosteric mechanism of p53 activation by small molecules for targeted anticancer therapy

Zawacka-Pankau, J.; Grinkevich, V. V.; Burmakin, M.; Vema, A.; Ridderstrale, K.; Issaeva, N.; Andreotti, V.; Dickinson, E. R.; Hedstrom, E.; Spinnler, C.; Inga, A.; Larsson, L.-G.; Karlen, A.; Tarasova, O.; Poroikov, V.; Lavrenov, S.; Preobrazhenskaya, M.; Wilhelm, M.; Barran, P. E.; Okorokov, A. L.; Selivanova, G.

10.1101/384248 — cancer biology — Posted on 2018-08-16

1403 Cofactors revisited - predicting the impact of flavoprotein-related diseases on a genome scale

Wegrzyn, A. B.; Stolle, S.; Rienksma, R. A.; Martins dos Santos, V. A. P.; Bakker, B. M.; Suarez-Diez, M.

10.1101/343624 — systems biology — Posted on 2018-08-15

1404 FADS1 and the timing of human adaptation to agriculture

Mathieson, S.; Mathieson, I.

10.1101/337998 — evolutionary biology — Posted on 2018-08-15

1405 The landscape of selection in 551 Esophageal Adenocarcinomas defines genomic biomarkers for the clinic

Frankell, A. M.; Jammula, S.; Li, X.; Contino, G.; Killcoyne, S. S.; Abbas, S.; Perner, J.; Bower, L.; Devonshire, G.; Ococks, E.; Grehan, N.; Mok, J.; O'Donovan, M.; Macrae, S.; Eldridge, M.; Tavare, S.; Fitzgerald, R. C.; The Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium,

10.1101/310029 — cancer biology — Posted on 2018-08-15

1406 Iroki: automatic customization and visualization of phylogenetic trees

Moore, R. M.; Harrison, A. O.; McAllister, S. M.; Wommack, K. E.

10.1101/106138 — bioinformatics — Posted on 2018-08-15

1407 Regional Striatal Cholinergic Involvement in Human Behavioural Flexibility

Bell, T.; Lindner, M.; Langdon, A.; Mullins, P. G.; Christakou, A.

10.1101/392233 — neuroscience — Posted on 2018-08-15

1408 Open-Source Food: Nutrition, Toxicology, and Availability of Wild Edible Greens in the East Bay

Stark, P. B.; Miller, D.; Carlson, T.; de Vasquez, K. R.

10.1101/385864 — ecology — Posted on 2018-08-15

1409 Chikungunya in Colombia: a description of an epidemic within the framework of a COPCORD study

Rueda, J. C.; Santos, A. M.; Angarita, J.-I.; Giraldo, R. B.; Saldarriaga, E.-L.; Ballesteros Munoz, J. G.; Forero, E.; Valencia, H.; Somoza, F.; Pelaez-Ballestas, I.; Cardiel, M. H.; Pavia, P. X.; Londono, J.

10.1101/389981 — epidemiology — Posted on 2018-08-15

1410 Medical Nonadherence, Cannabis Use, and Renal Outcome in Systemic Lupus Erythematosis

Jalil, B. A.; Qualls, C. R.; Cabacungan, R. J.; Sibbitt, W. L.; Gibb, J. I.; Noronha, L. E.; Fields, R. A.; Emil, N. S.; Fangtham, M.; Bankhurst, A. D.

10.1101/389973 — epidemiology — Posted on 2018-08-15

1411 Importance of vitamin D in critically ill children with subgroup analyses of sepsis and respiratory tract infections: a systematic review and meta-analysis

Cariolou, M.; Cupp, M. A.; Evangelou, E.; Tzoulaki, I.; Berlanga-Taylor, A. J.

10.1101/390476 — epidemiology — Posted on 2018-08-15

1412 Mortality attributable to seasonal influenza in Greece, 2013-2017: variation by type and age, and a possible harvesting effect

Lytras, T.; Pantavou, K.; Mouratidou, E.; Tsiodras, S.

10.1101/389411 — epidemiology — Posted on 2018-08-15

1413 Individual and temporal variation in pathogen load predicts long-term impacts of an emerging infectious disease

Wells, K.; Hamede, R. K.; Jones, M. E.; Hohenlohe, P. A.; Storfer, A.; McCallum, H. I.

10.1101/392324 — epidemiology — Posted on 2018-08-15

1414 Assessment of Menstrual Health Status and Evolution through Mobile Apps for Fertility Awareness

Symul, L.; Wac, K.; Hillard, P.; Salathe, M.

10.1101/385054 — epidemiology — Posted on 2018-08-15

1415 Discrepancies between observed data and predictions from mathematical modelling of the impact of screening interventions on Chlamydia trachomatis prevalence

Smid, J. H.; Althaus, C. L.; Low, N.

10.1101/389387 — epidemiology — Posted on 2018-08-15

1416 Extensive and deep sequencing of the Venter/HuRef genome for developing and benchmarking genome analysis tools

Zhou, B.; Arthur, J. G.; Ho, S. S.; Pattni, R.; Huang, Y.; Wong, W. H.; Urban, A. E.

10.1101/281709 — genomics — Posted on 2018-08-15

1417 Pharmacokinetics, Side Effects, and Anti-Hyperalgesic Efficacy of The Mglu5 Antagonist Fenobam.

Cavallone, L. F.; Montana, M. C.; Frey, K.; Kallogjeri, D.; Wages, J. M.; Rodebaugh, T. L.; Doshi, T.; Kharasch, E. D.; Gereau, R. W.

10.1101/391383 — neuroscience — Posted on 2018-08-15

1418 HMP16SData: Efficient Access to the Human Microbiome Project through Bioconductor

Schiffer, L.; Azhar, R.; Shepherd, L.; Ramos, M.; Geistlinger, L.; Huttenhower, C.; Dowd, J. B.; Segata, N.; Waldron, L.

10.1101/299115 — bioinformatics — Posted on 2018-08-15

1419 Recapitulating bone development for tissue regeneration through engineered mesenchymal condensations and mechanical cues

McDermott, A. M.; Herberg, S.; Mason, D. E.; Pearson, H. B.; Dawahare, J. H.; Collins, J. M.; Tang, R.; Patwa, A.; Grinstaff, M. W.; Kelly, D. J.; Alsberg, E.; Boerckel, J. D.

10.1101/157362 — bioengineering — Posted on 2018-08-15

1420 The Warburg effect and lactate signaling augment Fgf signaling to promote sensory-neural development in the otic vesicle

Riley, B.; Kantarci, H.; Gou, Y.

10.1101/392548 — developmental biology — Posted on 2018-08-15

1421 Quantifying spatiotemporal dynamics and noise in absolute microbiota abundances using replicate sampling

Ji, B. W.; Sheth, R. U.; Dixit, P. D.; Wang, H. H.; Vitkup, D.

10.1101/310649 — microbiology — Posted on 2018-08-15

1422 Lsm12 mediates Polη deubiquitination to help Saccharomyces cerevisiae resist oxidative stress

Yao, R.; Shi, L.; Wu, C.; Qiao, W.; Liu, L.; Wu, J.

10.1101/392415 — cell biology — Posted on 2018-08-15

1423 Elastic and Rigidified CENP-A Nucleosomes govern Centromeric Chromatin Plasticity

Melters, D. P.; Rakshit, T.; Pitman, M.; Grigoryev, S. A.; Bui, M.; Sturgill, D.; Papoian, G. A.; Dalal, Y.

10.1101/392787 — biochemistry — Posted on 2018-08-15

1424 LRRK2 kinase inhibitors induce a reversible effect in the lungs of non-human primates with no measurable pulmonary deficits

Baptista, M.; Merchant, K.; Barrett, T.; Bryce, D.; Ellis, M.; Estrada, A.; Fell, M.; Fiske, B.; Fuji, R.; Galatsis, P.; Henry, A.; Hill, S.; Hirst, W.; Houle, C.; Kennedy, M.; Liu, X.; Maddess, M.; Markgraf, C.; Mei, H.; Meier, W.; Ploch, S.; Royer, C.; Rudolph, K.; Sharma, A.; Stepan, A.; Steyn, S.; Trost, C.; Yin, Z.; Yu, H.; Wang, X.; Sherer, T.

10.1101/390815 — pharmacology and toxicology — Posted on 2018-08-15

1425 Nell2 regulates the contralateral-versus-ipsilateral visual projection as a layer-specific positional cue

Nakamoto, C.; Durward, E.; Horie, M.; Nakamoto, M.

10.1101/392597 — developmental biology — Posted on 2018-08-15

1426 Genetic control of cellular morphogenesis in Müller glia

Charlton-Perkins, M.; Almeida, A. D.; MacDonald, R. B.; Harris, W. A.

10.1101/392902 — cell biology — Posted on 2018-08-15

1427 The N-end Rule Pathway and Ubr1 mediate clearance of mis-translocated proteins from the cytosol via P2-encoded cellular location signals

Tran, A.

10.1101/392373 — cell biology — Posted on 2018-08-15

1428 Data-driven approaches for Tau-PET imaging biomarkers in Alzheimer’s disease

Vogel, J. W.; Mattsson, N.; Iturria-Medina, Y.; Strandberg, T. O.; Scholl, M.; Dansereau, C.; Villeneuve, S.; van der Flier, W. M.; Scheltens, P.; Bellec, P.; Evans, A. C.; Hansson, O.; Ossenkoppele, R.; the Alzheimer's Disease Neuroimaging Initiative, ; the Swedish BioFINDER study,

10.1101/244574 — neuroscience — Posted on 2018-08-15

1429 De novo mutations in autism spectrum disorders and an empirical test of the neutral DNA model

Zhang, Y.; Huang, S.

10.1101/231944 — evolutionary biology — Posted on 2018-08-15

1430 Targeted Genotyping of Variable Number Tandem Repeats with adVNTR

Bakhtiari, M.; Shleizer-Burko, S.; Gymrek, M.; Bansal, V.; Bafna, V.

10.1101/221754 — bioinformatics — Posted on 2018-08-15

1431 Principal component analysis-based unsupervised feature extraction applied to single-cell gene expression analysis

Taguchi, Y.-h.

10.1101/312892 — bioinformatics — Posted on 2018-08-15

1432 Detection and classification of hard and soft sweeps from unphased genotypes by multilocus genotype identity

Harris, A. M.; Garud, N. R.; DeGiorgio, M.

10.1101/281063 — evolutionary biology — Posted on 2018-08-15

1433 Ending AIDS: trends in the incidence of HIV in eastern and southern Africa

Williams, B. G.; Granich, R.

10.1101/383372 — epidemiology — Posted on 2018-08-15

1434 EWI-2 Inhibits Cell-Cell Fusion at the Virological Synapse

Whitaker, E. E.; Symeonides, M.; Munson, P. B.; Thali, M.

10.1101/296251 — microbiology — Posted on 2018-08-15

1435 High-throughput amplicon sequencing of the full-length 16S rRNA gene with single-nucleotide resolution

Callahan, B. J.; Wong, J.; Heiner, C.; Oh, S.; Theriot, C. M.; Gulati, A. S.; McGill, S. K.; Dougherty, M. K.

10.1101/392332 — microbiology — Posted on 2018-08-15

1436 Invasion genetics of the silver carp (Hypophthalmichthys molitrix) across North America: Differentiation of fronts, introgression, and eDNA detection

Stepien, C. A.; Elz, A. E.; Snyder, M. R.; Genetics and Genomics Group,

10.1101/392704 — genetics — Posted on 2018-08-15

1437 MicroRNAs are likely part of the molecular toolkit regulating adult reproductive diapause in the mosquito, Culex pipiens

Meuti, M.; Bautista-Jimenez, R.; Reynolds, J.

10.1101/392738 — zoology — Posted on 2018-08-15

1438 Bacterial cohesion predicts spatial distribution in the larval zebrafish intestine

Schlomann, B. H.; Wiles, T. J.; Wall, E. S.; Guillemin, K.; Parthasarathy, R.

10.1101/392316 — microbiology — Posted on 2018-08-15

1439 Kingdom-wide comparison reveals conserved diurnal gene expression in Archaeplastida

Ferrari, C.; Proost, S.; Janowski, M.; Becker, J.; Nikoloski, Z.; Bhattacharya, D.; Price, D.; Tohge, T.; Bar-Even, A.; Fernie, A.; Stitt, M.; Mutwil, M.

10.1101/387316 — evolutionary biology — Posted on 2018-08-15

1440 Narrowly confined and glomerulus-specific onset latencies of odor-evoked calcium transients in the periglomerular cells of the mouse main olfactory bulb

Homma, R.; Lv, X.; Sato, T.; Imamura, F.; Zeng, S.; Nagayama, S.

10.1101/392274 — neuroscience — Posted on 2018-08-15

1441 A feature selection strategy for gene expression time series experiments with hidden Markov models

Cardenas-Ovando, R. A.; Fernandez-Figueroa, E. A.; Rueda-Zarate, H. R.; Noguez, J.; Rangel-Escareno, C.

10.1101/392761 — bioinformatics — Posted on 2018-08-15

1442 Regional Striatal Cholinergic Involvement in Human Behavioural Flexibility

Bell, T.; Lindner, M.; Langdon, A.; Mullins, P. G.; Christakou, A.

10.1101/392233 — neuroscience — Posted on 2018-08-15

1443 Therapeutic effects of Hypoxia-Inducible Factor-1α (HIF-1α) on bone formation around implants in diabetic mice

Oh, S.-M.; Shin, J.-S.; Kim, I.-K.; Moon, J.-S.; Kim, J.-H.; Lee, S.-K.; Lee, J.-H.

10.1101/392670 — molecular biology — Posted on 2018-08-15

1444 Characterization of the Rosa roxbunghii Tratt transcriptome and analysis of MYB genes

Yan, H.; Huang, X.; Zhai, L.; Yang, Z.; Yi, Y.; Xiaolong Huang, Huiqing Yan, Lisheng Zhai, Zhengting Yang, Yin Yi,

10.1101/392720 — bioinformatics — Posted on 2018-08-15

1445 Delayed aneuploidy stress response of neural stem cells impairs adult lifespan in flies

Mirkovic, M.; Guilgur, L. G.; Passagem-Santos, D.; Oliveira, R. A.

10.1101/392746 — developmental biology — Posted on 2018-08-15

1446 EncoMPASS: an Encyclopedia of Membrane Proteins Analyzed by Structure and Symmetry

Aleksandrova, A. A.; Sarti, E.; Forrest, L. R.

10.1101/391961 — bioinformatics — Posted on 2018-08-15

1447 Transdiagnostic variations in impulsivity and compulsivity in obsessive-compulsive disorder and gambling disorder correlate with effective connectivity in cortical-striatal-thalamic-cortical circuits.

Parkes, L.; Tiego, J.; Aquino, K.; Braganza, L.; Chamberlain, S. R.; Fontenelle, L.; Harrison, B. J.; Lorenzetti, V.; Paton, B.; Razi, A.; Fornito, A.; Yucel, M.

10.1101/389320 — neuroscience — Posted on 2018-08-15

1448 Plasticity in striatal dopamine release is governed by release-independent depression and the dopamine transporter

Condon, M.; Platt, N.; Roberts, B.; Tseu, M.-Y.; Vietti-Michelina, S.; Threlfell, S.; Cragg, S. J.

10.1101/392753 — neuroscience — Posted on 2018-08-15

1449 Filter paper-based spin column for low throughput nucleic acid purification

Shi, R.; Lewis, R. R.; Panthee, D.

10.1101/392696 — molecular biology — Posted on 2018-08-15

1450 Localisation and hypersecretion of Nerve Growth Factor in breast Phyllodes tumours: evidence from a preliminary study

Kumar, A.; Raza, K.; Nag, T. C.; Srivastava, A.; Sehgal, R.

10.1101/392100 — cancer biology — Posted on 2018-08-15

1451 Key to identification of starch grains used as foods

Medeiros, A. M. L.; Marques, C. A.

10.1101/392209 — plant biology — Posted on 2018-08-15

1452 There and back again: metagenome-assembled genomes provide new insights into two thermal pools in Kamchatka, Russia

Wilkins, L.; Ettinger, C.; Jospin, G.; Eisen, J. A.

10.1101/392308 — microbiology — Posted on 2018-08-15

1453 Preliminary Study of the Potential Mechanism of CTSD in the Aging Process of Sepiella japonica: Fundamental Function Analysis

Guo, B.; Chen, Y.; Qi, P.; Ye, Y.; Lv, Z.; Zhang, X.; Xu, K.; Yu Chen, Pengzhi Qi, Yingying Ye, Zhenming Lv, Xiumei Zhang, Kaida Xu,

10.1101/392688 — genetics — Posted on 2018-08-15

1454 Biological control protects tropical forests

Wyckhuys, K. A.; Hughes, A.; Buamas, C.; Johnson, A. C.; Vasseur, L.; Reymondin, L.; Deguine, J.-P.; Sheil, D.

10.1101/391748 — ecology — Posted on 2018-08-15

1455 Transcription factor activity and nucleosome organisation in mitosis

Festuccia, N.; Owens, N.; Papadopoulou, T.; Gonzalez, I.; Tachtsidi, A.; Vandoermel-Pournin, S.; Gallego, E.; Gutierrez, N.; Dubois, A.; Cohen-Tannoudji, M.; Navarro, P.

10.1101/392241 — genomics — Posted on 2018-08-15

1456 Chicago and Dovetail Hi-C proximity ligation yield chromosome length scaffolds of Ixodes scapularis genome

Nuss, A. B.; Sharma, A.; Gulia-Nuss, M.

10.1101/392126 — genomics — Posted on 2018-08-15

1457 Extracellular electron transfer may be an overlooked contribution to pelagic respiration in humic-rich freshwater lakes

He, S.; Lau, M. P.; Linz, A. M.; Roden, E. E.; McMahon, K. D.

10.1101/392027 — ecology — Posted on 2018-08-15

1458 Modeling circRNAs expression pattern with integrated sequence and epigenetic features identifies H3K79me2 as regulators for circRNAs expression

Chen, J.-B.; Dong, S.-S.; Yao, S.; Duan, Y.-Y.; Hu, W.-X.; Chen, H.; Wang, N.-N.; Hao, R.-H.; Guo, M.-R.; Zhang, Y.-J.; Rong, Y.; Chen, Y.-X.; Thynn, H. N.; Zhou, F.-L.; Guo, Y.; Yang, T.-L.

10.1101/392019 — bioinformatics — Posted on 2018-08-15

1459 Protein Kinase A activity is regulated by actomyosin contractility during cell migration and is required for durotaxis

McKenzie, A. J.; Williams, T. F.; Svec, K. V.; Howe, A. K.

10.1101/392399 — cell biology — Posted on 2018-08-15

1460 Analysis and comparison of genome editing using CRISPResso2

Clement, K.; Rees, H.; Canver, M.; Gehrke, J.; Farouni, R.; Hsu, J.; Cole, M.; Liu, D. R.; Joung, J. K.; Bauer, D. E.; Pinello, L.

10.1101/392217 — bioinformatics — Posted on 2018-08-15

1461 Stable biphasic interfaces for open microfluidic platforms

Lee, U. N.; Berthier, J.; Yu, J.; Berthier, E.; Theberge, A. B.

10.1101/392258 — bioengineering — Posted on 2018-08-15

1462 A Ubiquitin-Binding Domain that Does Not Bind Ubiquitin

Lim, M.; Newman, J. A.; Williams, H. L.; Aitkenhead, H.; Gileadi, O.; Svejstrup, J.

10.1101/375832 — biochemistry — Posted on 2018-08-15

1463 The genomic determinants of adaptive evolution in a fungal pathogen

Grandaubert, J.; Dutheil, J. Y.; Stukenbrock, E. H.

10.1101/176727 — evolutionary biology — Posted on 2018-08-15

1464 Quality of eyeglass prescriptions from a low-cost wavefront autorefractor evaluated in rural India: results of a 708-participant field study

Durr, N. J.; Dave, S. R.; Lim, D.; Joseph, S.; Ravilla, T. D.; Lage, E.

10.1101/390625 — bioengineering — Posted on 2018-08-15

1465 Superior dispersal ability leads to persistent ecological dominance by Candida pseudoglaebosa in the Sarracenia purpurea metacommunity

Boynton, P. J.; Peterson, C. N.; Pringle, A.

10.1101/387753 — ecology — Posted on 2018-08-15

1466 Forecasting the global extent of invasion of the cereal pest Spodoptera frugiperda, the fall armyworm

Early, R.; Gonzalez-Moreno, P.; Murphy, S. T.; Day, R.

10.1101/391847 — ecology — Posted on 2018-08-15

1467 Reactivation of TAp73 tumor suppressor by protoporphyrin IX, a metabolite of aminolevulinic acid, induces apoptosis in TP53-deficient cancer cells

Sznarkowska, A.; Kostecka, A.; Kawiak, A.; Acedo, P.; Lion, M.; Inga, A.; Zawacka-Pankau, J.

10.1101/357293 — cancer biology — Posted on 2018-08-15

1468 The R package Rsubread is easier, faster, cheaper and better for alignment and quantification of RNA sequencing reads

Liao, Y.; Smyth, G. K.; Shi, W.

10.1101/377762 — bioinformatics — Posted on 2018-08-15

1469 Oxford Nanopore MinION sequencing enables rapid whole-genome assembly of Rickettsia typhi in a resource-limited setting

Elliott, I.; Batty, E. M.; Ming, D.; Robinson, M. T.; Nawtaisong, P.; de Cesare, M.; Newton, P. N.; Bowden, R.

10.1101/292102 — genomics — Posted on 2018-08-15

1470 The Tudor protein Veneno assembles the ping-pong amplification complex that produces viral piRNAs in Aedes mosquitoes

Joosten, J.; Miesen, P.; Pennings, B.; Jansen, P. W. T. C.; Huynen, M. A.; Vermeulen, M.; Van Rij, R. P.

10.1101/242305 — microbiology — Posted on 2018-08-15

1471 miR-10b Deficiency Affords Atherosclerosis Resistance

Nakahara, M.; Kobayashi, N.; Oka, M.; Nakano, K.; Okamura, T.; Yuo, A.; Saeki, K.

10.1101/248641 — cell biology — Posted on 2018-08-15

1472 Differential Recordings of Local Field Potential: A Genuine Tool to Quantify Functional Connectivity

Comte, J.-C.; Meyer, G.; Carponcy, J.; Salin, P. A.

10.1101/270439 — biophysics — Posted on 2018-08-14

1473 Coordinated cerebellar climbing fiber activity signals learned sensorimotor predictions

Heffley, W.; Song, E. Y.; Xu, Z.; Taylor, B.; Hughes, M. A.; McKinney, A.; Joshua, M.; Hull, C.

10.1101/281055 — neuroscience — Posted on 2018-08-14

1474 Rare, pathogenic germline variants in Fanconi Anemia genes increase risk for squamous lung cancer

Esai Selvan, M.; Klein, R. J.; Gumus, Z. H.

10.1101/269837 — genomics — Posted on 2018-08-14

1475 Mitochondria-encoded genes contribute to the evolution of heat and cold tolerance among Saccharomyces species

Li, X. C.; Peris, D.; Hittinger, C. T.; Sia, E. A.; Fay, J. C.

10.1101/390500 — evolutionary biology — Posted on 2018-08-14

1476 The Subjective Value of Cognitive Effort is Encoded by a Domain-General Valuation Network

Westbrook, A.; Lamichhane, B.; Braver, T.

10.1101/391805 — neuroscience — Posted on 2018-08-14

1477 Comparing the metabolic fates of BALB/c mice maintained on cafeteria-style diets with differential nutritive values

Zaid, M.; Ameer, F.; Ali, A.; Shoukat, Z.; Rashid, R.; Iqbal, I.; Zaidi, N.

10.1101/391821 — biochemistry — Posted on 2018-08-14

1478 Decoupling between causal understanding and awareness during learning and inference

Lee, J.; Kralik, J. D.; Cha, Y.; Lee, J. H.; Lee, S. W.

10.1101/391938 — neuroscience — Posted on 2018-08-14

1479 Reading at the speed of speech: the rate of eye movements aligns with auditory language processing

Gagl, B.; Golch, J.; Hawelka, S.; Sassenhagen, J.; Poeppel, D.; Fiebach, C. J.

10.1101/391896 — neuroscience — Posted on 2018-08-14

1480 MeCP2-E1 isoform is a dynamically expressed, weakly DNA-bound protein with different protein and DNA interactions compared to MeCP2-E2

10.1101/392092 — biochemistry — Posted on 2018-08-14

1481 Integrative analyses of multi-tissue Hi-C and eQTL data demonstrate close spatial proximity between eQTLs and their target genes

Yu, J.; Hu, M.; Li, C.

10.1101/392266 — systems biology — Posted on 2018-08-14

1482 Epigenetic inactivation of miR-203 as a key step in neural crest epithelial-to-mesenchymal transition

Sanchez-Vasquez, E.; Bronner, M.; Strobl-Mazzulla, P. H.

10.1101/392142 — developmental biology — Posted on 2018-08-14

1483 Structural basis for ligand modulation of the CCR2 conformational landscape

Taylor, B. C.; Lee, C. T.; Amaro, R. E.

10.1101/392068 — biophysics — Posted on 2018-08-14

1484 Mitochondrial DNA and temperature tolerance in lager yeasts

Baker, E. P.; Peris, D.; Moriarty, R. V.; Li, X. C.; Fay, J. C.; Hittinger, C. T.

10.1101/391946 — genetics — Posted on 2018-08-14

1485 A Chemical Toolbox for the Study of Bromodomains and Epigenetic Signaling

Wu, Q.; Heidenreich, D.; Zhou, S.; Ackloo, S.; Deblois, G.; Duan, S.; Nakka, K.; Dilworth, J.; Lupien, M.; Brennan, P. E.; Arrowsmith, C. H.; Mueller, S.; Fedorov, O.; Filippakopoulos, P.; Knapp, S.

10.1101/391870 — cell biology — Posted on 2018-08-14

1486 Uncoupled activation and cyclisation in catmint reductive terpenoid biosynthesis

Lichman, B.; Kamileen, M.; Tichman, G.; Saalbach, G.; Stevenson, C.; Lawson, D.; O'Connor, S.

10.1101/391953 — biochemistry — Posted on 2018-08-14

1487 State conditional optogenetic entrainment of the septo-hippocampal circuit reveals the importance of endogenous theta oscillations as a unit of spatial metric

Mouchati, P. R.; Holmes, G. L.; Barry, J. M.

10.1101/392050 — neuroscience — Posted on 2018-08-14

1488 CRISPR/Cas9-mediated gene deletion of the ompA gene in an Enterobacter gut symbiont impairs biofilm formation and reduces gut colonization of Aedes aegypti mosquitoes

Hegde, S.; Nilyanimit, P.; Kozlova, E.; Narra, H. P.; Sahni, S. K.; Hughes, G. L.

10.1101/389957 — microbiology — Posted on 2018-08-14

1489 Site-specific K63 ubiquitinomics reveals post-initiation regulation of ribosomes under oxidative stress

Back, S.; Vogel, C.; Silva, G. M.

10.1101/392076 — molecular biology — Posted on 2018-08-14

1490 Understanding and predicting extreme wildfires in the contiguous United States

Joseph, M. B.; Rossi, M. W.; Mietkiewicz, N. P.; Mahood, A. L.; Cattau, M. E.; St. Denis, L. A.; Nagy, R. C.; Iglesias, V.; Abatzoglou, J. T.; Balch, J. K.

10.1101/384115 — ecology — Posted on 2018-08-14

1491 Magic-BLAST, an accurate DNA and RNA-seq aligner for long and short reads

Boratyn, G. M.; Thierry-Mieg, J.; Thierry-Mieg, D.; Busby, B.; Madden, T. L.

10.1101/390013 — bioinformatics — Posted on 2018-08-14

1492 First evidence that intrinsic fetal heart rate variability exists and is affected by chronic hypoxia

Frasch, M. G.; Herry, C.; Niu, Y.; Giussani, D. A.

10.1101/242107 — physiology — Posted on 2018-08-14

1493 A Bayesian Mixture Modelling Approach For Spatial Proteomics

Crook, O. M.; Mulvey, C. M.; Kirk, P. D. W.; Lilley, K. S.; Gatto, L.

10.1101/282269 — systems biology — Posted on 2018-08-14

1494 Sequence-to-structure dependence of isolated IgG Fc complex biantennary N-glycans: A molecular dynamics study

Harbison, A. M.; Brosnan, L.; Fenlon, K.; Fadda, E.

10.1101/392001 — biophysics — Posted on 2018-08-14

1495 Loss of leaf-out and flowering synchrony under global warming

Zohner, C.; Mo, L.; Renner, S. S.

10.1101/391714 — ecology — Posted on 2018-08-14

1496 Integrative analysis of transcriptomic and clinical data uncovers the tumor suppressive activity of MITF in prostate cancer.

Valcarcel, L.; Macchia, A.; Martin, N.; Cortazar, A. R.; Schaub, A.; Pujana, M.; Fernandez, S.; Lacasa, I.; Santos, A.; Loizaga, A.; Unda, M.; Hermanova, I.; Astobiza, I.; Graupera, M.; Starkova, J.; Sutherland, J.; Barrio, R.; Aransay, A. M.; Carracedo, A.; Torrano, V.

10.1101/391763 — cancer biology — Posted on 2018-08-14

1497 Deforming the metric of cognitive maps distorts memory

Bellmund, J. L. S.; Ruiter, T. A.; Nau, M.; Barry, C.; Doeller, C. F.

10.1101/391201 — neuroscience — Posted on 2018-08-14

1498 Whole-head recording of chemosensory activity in the marine annelid Platynereis dumerilii

Chartier, T. F.; Deschamps, J.; Duerichen, W.; Jekely, G.; Arendt, D.

10.1101/391920 — neuroscience — Posted on 2018-08-14

1499 Mathematical modelling reveals how MeCP2 restrains transcriptional elongation in human neurons

Cholewa-Waclaw, J.; Shah, R.; Webb, S.; Chhatbar, K.; Ramsahoye, B.; Pusch, O.; Yu, M.; Greulich, P.; Waclaw, B.; Bird, A.

10.1101/391904 — biophysics — Posted on 2018-08-14

1500 Single-axon-resolution intravital imaging reveals a rapid onset form of Wallerian degeneration in the adult neocortex

Canty, A. J.; Jackson, J. S.; Huang, L.; Trabalza, A.; Bass, C.; Little, G.; De Paola, V.

10.1101/391425 — neuroscience — Posted on 2018-08-14

1501 Supra-threshold psychoacoustics and envelope-following response relations: normal-hearing, synaptopathy and cochlear gain loss

Verhulst, S.; Ernst, F.; Garrett, M.; Vasilkov, V.

10.1101/391672 — neuroscience — Posted on 2018-08-14

1502 Refinement of anesthetic choice in procedures preceding psychopharmacological studies

Herbst, L.; Gaigher, T.; Siqueira, A.; Joca, S.; Sampaio, K.; Beijamini, V.

10.1101/390583 — neuroscience — Posted on 2018-08-14

1503 Spatial attention follows category-based attention during naturalistic visual search: evidence from MEG decoding

Battistoni, E.; Kaiser, D.; Hickey, C.; Peelen, M. V.

10.1101/390807 — neuroscience — Posted on 2018-08-14

1504 Mitochondria-encoded genes contribute to the evolution of heat and cold tolerance among Saccharomyces species

Li, X. C.; Peris, D.; Hittinger, C. T.; Sia, E. A.; Fay, J. C.

10.1101/390500 — evolutionary biology — Posted on 2018-08-14

1505 Intracellular mechanisms of fungal space searching in microenvironments

Held, M.; Kaspar, O.; Edwards, C.; Nicolau, D. V.

10.1101/391797 — cell biology — Posted on 2018-08-14

1506 The Complete Chloroplast Genome of Dendrobium nobile, an endangered medicinal orchid from Northeast India and its comparison with related chloroplast genomes of Dendrobium species.

Konhar, R.; Debnath, M.; Bhattacharjee, A.; Sundar, D.; Tandon, P.; Dash, D.; Biswal, D. K.

10.1101/316778 — evolutionary biology — Posted on 2018-08-14

1507 A widespread coral-infecting apicomplexan contains a plastid encoding chlorophyll biosynthesis

Kwong, W. K.; del Campo, J.; Mathur, V.; Vermeij, M. J. A.; Keeling, P. J.

10.1101/391565 — microbiology — Posted on 2018-08-14

1508 Statistical Inference Relief (STIR) feature selection

Le, T. T.; Urbanowicz, R. J.; Moore, J. H.; McKinney, B. A.

10.1101/359224 — bioinformatics — Posted on 2018-08-14

1509 Modeling Spatial Correlation of Transcripts With Application to Developing Pancreas

Liu, R.; Mignardi, M.; Jones, R.; Enge, M.; Kim, S. K.; Quake, S. R.; Zou, J.

10.1101/391433 — bioinformatics — Posted on 2018-08-14

1510 The relationship between transmission time and clustering methods in Mycobacterium tuberculosis epidemiology

Meehan, C. J.; Moris, P.; Kohl, T. A.; Pecerska, J.; Akter, S.; Merker, M.; Utpatel, C.; Beckert, P.; Gehre, F.; Lempens, P.; Stadler, T.; Kaswa, M. K.; Kuhnert, D.; Niemann, S.; de Jong, B. C.

10.1101/302232 — epidemiology — Posted on 2018-08-14

1511 Mutations in nucleoporin NUP88 cause lethal neuromuscular disorder

Bonnin, E.; Cabochette, P.; Filosa, A.; Juehlen, R.; Komatsuzaki, S.; Hezwani, M.; Dickmanns, A.; Martinelli, V.; Vermeersch, M.; Supply, L.; Martins, N.; Pirenne, L.; Ravenscroft, G.; Lombard, M.; Port, S. A.; Spillner, C.; Janssens, S.; Roets, E.; Van Dorpe, J.; Lammens, M.; Kehlenbach, R. H.; Ficner, R.; Laing, N.; Hoffmann, K.; Vanhollebeke, B.; Fahrenkrog, B.

10.1101/347179 — cell biology — Posted on 2018-08-14

1512 Cyclin B3 is specifically required for metaphase to anaphase transition in mouse oocyte meiosis I

Li, Y.; Wang, L.; Zhang, L.; He, Z.; Feng, G.; Sun, H.; Wang, J.; Li, Z.; Liu, C.; Han, J.; Mao, J.; Yuan, X.; Jiang, L.; Zhang, Y.; Zhou, Q.; Li, W.

10.1101/390351 — cell biology — Posted on 2018-08-14

1513 Realistic in silico generation and augmentation of single cell RNA-seq data using Generative Adversarial Neural Networks

Marouf, M.; Machart, P.; Magruder, D. S. S.; Bansal, V.; Kilian, C.; Krebs, C. F.; Bonn, S.

10.1101/390153 — bioinformatics — Posted on 2018-08-14

1514 POFUT2-mediated O-glycosylation of MIC2 is dispensable for Toxoplasma gondii tachyzoites

Khurana, S.; Coffey, M. J.; John, A.; Uboldi, A. D.; Huynh, M.-H.; Stewart, R. J.; Carruthers, V. B.; Tonkin, C.; Goddard-Borger, E. D.; Scott, N.

10.1101/391623 — microbiology — Posted on 2018-08-14

1515 Genomic from Plasmodium falciparum field isolates from Benin allows the identification of PfEMP1 variants by LC-MS/MS at the patient’s level

kamaliddin, C.; Rombaut, D.; Guillochon, E.; Royo, J.; Ezinmegnon, S.; Huguet, S.; Guemouri, S.; Peirera, C.; Broussard, C.; Alao, J.; Aubouy, A.; Guillonneau, F.; Deloron, P.; Bertin, G.

10.1101/391615 — microbiology — Posted on 2018-08-14

1516 A previously missed population of antigen-specific CD8 T cells divides in the blood after vaccination

Simonetti, S.; Natalini, A.; Folgori, A.; Capone, S.; Nicosia, A.; Santoni, A.; Di Rosa, F.

10.1101/391664 — immunology — Posted on 2018-08-14

1517 Whole-genome sequencing of three native cattle breeds originating from the northernmost cattle farming regions

Weldenegodguad, M.; Popov, R.; Pokharel, K.; Ammosov, I.; Yao, M.; Ivanova, Z.; Kantanen, J.

10.1101/390369 — genomics — Posted on 2018-08-14

1518 Fixation time in evolutionary graphs: a mean field approach

Hajihashemi jazi, M.; Aghababaei Samani, K.

10.1101/391508 — evolutionary biology — Posted on 2018-08-14

1519 Potential impacts of transport infrastructure and traffic on bird conservation in Swedish Special Protection Areas

Helldin, J. O.

10.1101/351692 — ecology — Posted on 2018-08-14

1520 A single-cell level and connectome-derived computational model of the Drosophila brain

Huang, Y.-C.; Wang, C.-T.; Su, T.-S.; Kao, K.-W.; Lin, Y.-J.; Chiang, A.-S.; Lo, C.-C.

10.1101/391474 — bioinformatics — Posted on 2018-08-14

1521 Transcriptomic response in symptomless roots of clubroot infected kohlrabi mirrors resistant plants

Ciaghi, S.; Schwelm, A.; Neuhauser, S.

10.1101/391516 — plant biology — Posted on 2018-08-14

1522 Mining unknown porcine protein isoforms by tissue-based map of proteome enhances the pig genome annotation

Zhao, P.; Zheng, X.; Yu, Y.; Hou, Z.; Diao, C.; Wang, H.; Kang, H.; Ning, C.; Li, J.; Feng, W.; Wang, W.; Liu, G. E.; Li, B.; Smith, J.; Chamba, Y.; Liu, J.-F.

10.1101/391466 — genomics — Posted on 2018-08-14

1523 Cyclin B3 promotes APC/C activation and anaphase I onset in oocyte meiosis

Karasu, M. E.; Bouftas, N.; Keeney, S.; Wassmann, K.

10.1101/390161 — cell biology — Posted on 2018-08-14

1524 Mechanistic and experimental models of cell migration reveal the importance of intercellular interactions in cell invasion

Matisaka, O.; Baker, R.; Shah, E.; Simpson, M.

10.1101/391557 — biophysics — Posted on 2018-08-14

1525 Reactive Centre Loop Dynamics and Serpin Specificity

Marijanovic, E. M.; Fodor, J.; Riley, B. T.; Porebski, B. T.; Costa, M. G.; Kass, I.; Hoke, D. E.; McGowan, S.; Buckle, A. M.

10.1101/391482 — biochemistry — Posted on 2018-08-14

1526 Role of the H subunit C-terminal domain in the assembly of the vacuolar H+-ATPase

Sharma, S.; Oot, R. A.; Wilkens, S.

10.1101/391656 — biochemistry — Posted on 2018-08-14

1527 Development of a multi-locus CRISPR gene drive system in budding yeast

Yan, Y.; Finnigan, G. C.

10.1101/391334 — synthetic biology — Posted on 2018-08-14

1528 Exogenous calcium ions enhance patulin adsorption capability of Saccharomyces cerevisiae

Luo, Y.; Liu, X.; Han, Y.; Li, J.

10.1101/391573 — microbiology — Posted on 2018-08-14

1529 Nonsteroidal anti-inflammatory drugs alter the microbiota and exacerbate Clostridium difficile colitis while dysregulating the inflammatory response

Maseda, D.; Zackular, J. P.; Trindade, B.; Kirk, L.; Crofford, L. J.; Schloss, P. D.; Roxas, J. L.; Viswanathan, V. K.; Vedantam, G.; Rogers, L. M.; Washington, M. K.; Skaar, E. P.; Aronoff, D. M.

10.1101/391607 — microbiology — Posted on 2018-08-14

1530 Abundance of whales in West and East Greenland in summer 2015

Heide-Jorgensen, M. P.; Rasmussen, M. H.; Nielsen, R. D.; Nielsen, N. H.; Larsen, R. S.; Boye, T. K.; Hansen, R. G.; Sinding, M.-H. S.; Tervo, O.

10.1101/391680 — ecology — Posted on 2018-08-14

1531 Fine Tuning of Histone Demethylase KDM6A/B Improves the Development of Nuclear Transfer Embryo

Yang, L.; Song, L.; Liu, X.; Bai, L.; Li, G.

10.1101/390484 — cell biology — Posted on 2018-08-14

1532 Surface Plasmon Resonance Imaging of Excitable Cells

Howe, C. L.; Webb, K. F.; Abayzeed, S. A.; Anderson, D. J.; Denning, C.; Russell, N. A.

10.1101/390948 — bioengineering — Posted on 2018-08-14

1533 Cortical circuit alterations precede disease onset in Huntington’s disease mice

Neuner, J.; Schulz-Trieglaff, E. K.; Gutierrez-Angel, S.; Hosp, F.; Mann, M.; Arzberger, T.; Klein, R.; Liebscher, S.; Dudanova, I.

10.1101/391771 — neuroscience — Posted on 2018-08-14

1534 Proteomic analysis of RNA-dependent chromatin association of nuclear proteins

Hiragami-Hamada, K.; Tani, N.; Nakayama, J.-i.

10.1101/391755 — molecular biology — Posted on 2018-08-14

1535 The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1

Volkmar, N.; Menzies, S. A.; van den Boomen, D. J.; Timms, R. T.; Dickson, A. S.; Nathan, J. A.; Lehner, P. J.

10.1101/391789 — cell biology — Posted on 2018-08-14

1536 Heritability, selection, and the response to selection in the presence of phenotypic measurement error: effects, cures, and the role of repeated measurements

Ponzi, E.; Keller, L. F.; Bonnet, T.; Muff, S.

10.1101/247189 — evolutionary biology — Posted on 2018-08-14

1537 Maintaining trunk neural crest cells as crestospheres

Mohlin, S.; Kunttas, E.; Persson, C. U.; Abdel-Haq, R.; Castillo, A.; Murko, C.; Bronner, M. E.; Kerosuo, L.

10.1101/391599 — developmental biology — Posted on 2018-08-14

1538 Distinct contributions of tensile and shear stress on E-cadherin levels during morphogenesis

Kale, G. R.; Yang, X.; Philippe, J.-M.; Mani, M.; Lenne, P.-F.; Lecuit, T.

10.1101/255158 — cell biology — Posted on 2018-08-14

1539 Two stochastic processes shape diverse senescence patterns in a single-cell organism

Steiner, U. K.; Lenart, A.; Ni, M.; Chen, P.; Song, X.; Taddei, F.; Lindner, A.; Vaupel, J.

10.1101/105387 — systems biology — Posted on 2018-08-14

1540 Larger Numbers can Impede Adaptation in Asexual Populations despite Entailing Greater Genetic Variation

Chavhan, Y. D.; Ali, S. I.; Dey, S.

10.1101/076760 — evolutionary biology — Posted on 2018-08-14

1541 Hydrogenotrophic methanogenesis in archaeal phylum Verstraetearchaeota reveals the shared ancestry of all methanogens

Berghuis, B. A.; Yu, F. B.; Schulz, F.; Blainey, P. C.; Woyke, T.; Quake, S.

10.1101/391417 — microbiology — Posted on 2018-08-14

1542 Quantifying the risk of hemiplasy in phylogenetic inference

Guerrero, R. F.; Hahn, M. W.

10.1101/391391 — evolutionary biology — Posted on 2018-08-14

1543 AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance

Nagy, S.; Maurer, G. W.; Hentze, J. L.; Kondo, S.; Rose, M.; Werge, T. M.; Rewitz, K.

10.1101/391722 — neuroscience — Posted on 2018-08-14

1544 DdcA antagonizes a bacterial DNA damage checkpoint

Burby, P. E.; Simmons, Z. W.; Simmons, L. A.

10.1101/391730 — microbiology — Posted on 2018-08-14

1545 Cancer cell CCR2 orchestrates suppression of the adaptive immune response

Fein, M. R.; He, X. Y.; Almeida, A. S.; Bruzas, E.; Pommier, A.; Eberhardt, A.; Fearon, D. T.; Wilkinson, J. E.; dos Santos, C. O.; Egeblad, M.

10.1101/390187 — cancer biology — Posted on 2018-08-13

1546 Theoretical principles of multiscale spatiotemporal control of neuronal networks: a complex systems perspective

Dehghani, N.

10.1101/097618 — neuroscience — Posted on 2018-08-13

1547 A simple high-throughput approach identifies actionable drug responses in patient-derived tumor organoids

Phan, N.; Hong, J. J.; Tofig, B.; Mapua, M.; Elashoff, D.; Moatamed, N. A.; Huang, J.; Memarzadeh, S.; Damoiseaux, R.; Soragni, A.

10.1101/138412 — cancer biology — Posted on 2018-08-13

1548 Boundaries in Spatial Cognition: How They Look is More Important than What They Do

Negen, J.; Sandri, A.; Lee, S. A.; Nardini, M.

10.1101/391037 — animal behavior and cognition — Posted on 2018-08-13

1549 High-dimensional geometry of population responses in visual cortex

Stringer, C.; Pachitariu, M.; Steinmetz, N.; Carandini, M.; Harris, K. D.

10.1101/374090 — neuroscience — Posted on 2018-08-13

1550 A Drosophila Model for Behavioral Sleep Modification

Belfer, S. J.; Bashaw, A. G.; Perlis, M. L.; Kayser, M. S.

10.1101/391375 — neuroscience — Posted on 2018-08-13

1551 Sucrose Intensity coding and decision-making in taste cortices

Fonseca, E.; de Lafuente, V.; Simon, S. A.; Gutierrez, R.

10.1101/391342 — neuroscience — Posted on 2018-08-13

1552 Multi-Scale Neural Sources of EEG: Genuine, Equivalent, and Representative

Nunez, P. L.; Nunez, M. D.; Srinivasan, R.

10.1101/391318 — neuroscience — Posted on 2018-08-13

1553 Microscopic and Macroscopic Response of a Cortical Neuron to an External Electric Field Computed with the Boundary Element Fast Multipole Method

Makarov, S. N.; Noetscher, G. M.; Sundaram, P.

10.1101/391060 — neuroscience — Posted on 2018-08-13

1554 Visuomotor Control of Ankle Joint using Position vs. Force

Farjadian, A. B.; Nabian, M.; Hartman, A.; Yen, S.-C.; Nasseroleslami, B.

10.1101/391367 — neuroscience — Posted on 2018-08-13

1555 Resolving within-host malaria parasite diversity using single-cell sequencing

Nkhoma, S. C.; Trevino, S. G.; Gorena, K. M.; Nair, S.; Khoswe, S.; Jett, C.; Garcia, R.; Daniel, B.; Dia, A.; Terlouw, D. J.; Ward, S. A.; Anderson, T. J.; Cheeseman, I. H.

10.1101/391268 — genetics — Posted on 2018-08-13

1556 The genome of the soybean cyst nematode (Heterodera glycines) reveals complex patterns of duplications involved in the evolution of parasitism genes

Masonbrink, R. E.; Maier, T. R.; Muppirala, U.; Seetharam, A. S.; Lord, E.; Juvale, P.; Schmutz, J.; Johnson, N. T.; Korkin, D.; Mitchum, M. G.; Mimee, B.; Eves-van den Akker, S.; Hudson, M.; Severin, A. J.; Baum, T. J.

10.1101/391276 — genomics — Posted on 2018-08-13

1557 An efficient genome editing strategy to generate putative null mutants in Caenorhabditis elegans using CRISPR/Cas9

Sternberg, P. W.; Wang, H.; Park, H.; Liu, J.

10.1101/391243 — genetics — Posted on 2018-08-13

1558 Spatial dynamics of brain functional domains: A new avenue to study time-varying brain function

Iraji, A.; Fu, Z.; Damarajua, E.; Belger, A.; Ford, J. M.; McEwen, S.; Mathalon, D. H.; Mueller, B. A.; Pearlson, G. D.; Potkin, S. G.; Preda, A.; Turner, J. A.; Vaidya, J. G.; van Erp, T. G. M.; Calhoun, V. D.

10.1101/391094 — neuroscience — Posted on 2018-08-13

1559 Cancer cell CCR2 orchestrates suppression of the adaptive immune response

Fein, M. R.; He, X. Y. R.; Almeida, A. S.; Bruzas, E. S.; Pommier, A.; Eberhardt, A.; Fearon, D. T.; Wilkinson, J. E.; dos Santos, C. O.; Egeblad, M.

10.1101/390187 — cancer biology — Posted on 2018-08-13

1560 Which way is the bookstore? A closer look at the judgments of relative directions task.

Huffman, D. J.; Ekstrom, A. D.

10.1101/391326 — animal behavior and cognition — Posted on 2018-08-13

1561 Could future gene therapy prevent aging diseases?

Oliynyk, R. T.

10.1101/390773 — genetics — Posted on 2018-08-13

1562 Evolution of Portulacineae marked by gene tree conflict and gene family expansion associated with adaptation to harsh environments

Wang, N.; Yang, Y.; Moore, M. J.; Brockington, S. F.; Walker, J. F.; Brown, J. W.; Liang, B.; Feng, T.; Edwards, C.; Mikenas, J.; Olivieri, J.; Hutchison, V.; Timoneda, A.; Stoughton, T.; Puente, R.; Majure, L.; Eggli, U.; Smith, S. A.

10.1101/294546 — evolutionary biology — Posted on 2018-08-13

1563 Detection of Amyotrophic Lateral Sclerosis (ALS) via Acoustic Analysis

Norel, R.; Pietrowicz, M.; Agurto, C.; Rishoni, S.; Cecchi, G.

10.1101/383414 — neuroscience — Posted on 2018-08-13

1564 Micro computed tomography as an accessible imaging platform for exploring organism development and human disease modeling

Schoborg, T.; Smith, S.; Smith, L.; Morris, H. D.; Rusan, N. M.

10.1101/391300 — developmental biology — Posted on 2018-08-13

1565 Fast, versatile, and quantitative annotation of complex images

Bates, K.; Jiang, S.; Bates, R.; Chaudhary, S.; Jackson-Holmes, E.; Jue, M.; McCaskey, E.; Goldman, D.; Lu, H.

10.1101/391169 — bioengineering — Posted on 2018-08-13

1566 Shear stress mediates metabolism and growth in electroactive biofilms

Jones, A.-A. D.; Buie, C. R.

10.1101/391029 — microbiology — Posted on 2018-08-13

1567 Pleotropic effects of mutations in the effector domain of influenza A virus NS1 protein

Pereira, C. F.; Wise, H. M.; Kurian, D.; Pinto, R. M.; Amorim, M. J.; Gill, A. C.; Digard, P.

10.1101/390690 — microbiology — Posted on 2018-08-13

1568 Variants in regulatory elements of PDE4D associate with Major Mental Illness in the Finnish population

Sinha, V.; Vuoti, L.-U.; Ortega-Alonso, A.; Torniainen-Holm, M.; Therman, S.; Tuulio-Henriksson, A.; Jylhä, P.; Kaprio, J.; Hovatta, I.; Isometsä, E.; Cannon, T. D.; Lonnqvist, J.; Paunio, T.; Suvisaari, J.; Hennah, W.

10.1101/390518 — genetics — Posted on 2018-08-13

1569 A randomised controlled trial of an Intervention to Improve Compliance with the ARRIVE guidelines (IICARus)

Hair, K.; Macleod, M. R.; Sena, E. S.; The IICARus Collaboration,

10.1101/370874 — scientific communication and education — Posted on 2018-08-13

1570 The splicing regulator Prp31 prevents retinal degeneration in Drosophila by regulating Rhodopsin levels

Lehmann, M.; Hebbar, S.; Behrens, S.; Leng, W.; Yuan, M.; Winkler, S.; Knust, E.

10.1101/386433 — genetics — Posted on 2018-08-13

1571 Cargo diffusion shortens single-kinesin runs at low viscous drag

Wilson, J. O.; Quint, D. A.; Gopinathan, A.; Xu, J.

10.1101/391284 — biophysics — Posted on 2018-08-13

1572 Reconciling fMRI and EEG indices of attentional modulations in human visual cortex

Itthipuripat, S.; Sprague, T.; Serences, J.

10.1101/391193 — neuroscience — Posted on 2018-08-13

1573 The genetics of the mood disorder spectrum: genome-wide association analyses of over 185,000 cases and 439,000 controls

Coleman, J.; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, ; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, ; Breen, G.

10.1101/383331 — genomics — Posted on 2018-08-13

1574 Multiple interfacial hydration of dihydro-sphingomyelin bilayer reported by the Laurdan fluorescence

Watanabe, N.; Goto, Y.; Suga, K.; Nyholm, T. K. M.; Slotte, J. P.; Umakoshi, H.

10.1101/391128 — biophysics — Posted on 2018-08-13

1575 Structural basis of altered potency and efficacy displayed by a major in vivo metabolite of the anti-diabetic PPARγ drug pioglitazone

Mosure, S.; Shang, J.; Brust, R.; Zheng, J.; Griffin, P.; Kojetin, D.

10.1101/351346 — biochemistry — Posted on 2018-08-13

1576 Trajectory changes are susceptible to change blindness manipulations

Jaquiery, M.; Andermane, N.; Chrisley, R.

10.1101/391359 — animal behavior and cognition — Posted on 2018-08-13

1577 Resistant potato starch fuels beneficial host-microbe interactions in the gut

Trachsel, J.; Briggs, C.; Gabler, N. K.; Allen, H. K.; Loving, C. L.

10.1101/389007 — systems biology — Posted on 2018-08-13

1578 Cracking the problem of neural representations of abstract words: grounding word meanings in language itself

Hulten, A.; van Vliet, M.; Lammi, L.; Kivisaari, S.; Lindh-Knuutila, T.; Faisal, A.; Salmelin, R.

10.1101/391052 — neuroscience — Posted on 2018-08-13

1579 droplet-Tn-Seq combines microfluidics with Tn-Seq identifying complex single-cell phenotypes

Thibault, D.; Wood, S.; Jensen, P.; van Opijnen, T.

10.1101/391045 — microbiology — Posted on 2018-08-13

1580 Engineering a model cell for rational tuning of GPCR signaling

Shaw, W. M.; Yamauchi, H.; Mead, J.; Gowers, G. F.; Oling, D.; Larsson, N.; Wigglesworth, M.; Ladds, G.; Ellis, T.

10.1101/390559 — synthetic biology — Posted on 2018-08-13

1581 Surge of Corticocardiac Coupling in SHRSP Rats Exposed to Forebrain Cerebral Ischemia

Tian, F.; Liu, T.; Xu, G.; Ghazi, T.; Sajjad, A.; Farrehi, P.; Wang, M. M.; Borjigin, J.

10.1101/388983 — physiology — Posted on 2018-08-13

1582 Pleotropic effects of mutations in the effector domain of influenza A virus NS1 protein

Pereira, C. F.; Wise, H. M.; Kurian, D.; Pinto, R. M.; Amorim, M. J.; Gill, A. C.; Digard, P.

10.1101/390690 — microbiology — Posted on 2018-08-13

1583 Conserved phosphorylation hotspots in eukaryotic protein domain families

Strumillo, M. J.; Oplova, M.; Vieitez, C.; Ochoa, D.; Shahraz, M.; Busby, B. P.; Sopko, R.; Studer, R. A.; Perrimon, N.; Panse, V. G.; Beltrao, P.

10.1101/391185 — cell biology — Posted on 2018-08-13

1584 The dynamics of ERK signaling in melanoma, and the response to BRAF or MEK inhibition, are cell cycle dependent.

Simpson, C. M.; Ferrari, N.; Calvo, F.; Bakal, C.

10.1101/306571 — cancer biology — Posted on 2018-08-13

1585 Quality of eyeglass prescriptions from a low-cost wavefront autorefractor evaluated in rural India: results of a 708-participant field study

Durr, N. J.; Dave, S. R.; Lim, D.; Joseph, S.; Ravilla, T. D.; Lage, E.

10.1101/390625 — bioengineering — Posted on 2018-08-13

1586 Distinct pattern of autofluorescence of the skin and fingernails of acute ischemic stroke patients: A novel diagnostic biomarker for acute ischemic stroke

Wu, D.; Zhang, M.; Tao, Y.; Li, Y.; Zhang, S.; Chen, X.; Ying, W.

10.1101/310904 — neuroscience — Posted on 2018-08-13

1587 S100A4 inhibits cell proliferation by interfering with the RAGE V domain-S100A1

Yu, C.; Khan, M. I.; Yuan, T.; Chou, R.-H.

10.1101/391136 — biochemistry — Posted on 2018-08-13

1588 Estimating Individual Contributions to Complex DNA SNP Mixtures

Ricke, D.; Fremont-Smith, P.; Watkins, J.; Boettcher, T.; Schwoebel, E.

10.1101/391086 — bioinformatics — Posted on 2018-08-13

1589 Using Drosophila behavioral assays to characterize terebrid venom-peptide bioactivity

Eriksson, A.; Anand, P.; Gorson, J.; Grijuc, C.; Hadelia, E.; Stewart, J.; Holford, M.; Claridge-Chang, A.

10.1101/391177 — animal behavior and cognition — Posted on 2018-08-13

1590 Genomewide significant regions in 43 Utah high-risk families implicate multiple genes involved in risk for completed suicide

Coon, H.; Darlington, T. M.; DiBlasi, E.; Callor, W. B.; Ferris, E.; Fraser, A.; Yu, Z.; William, N.; Das, S. C.; Crowell, S. E.; Chen, D.; Anderson, J. S.; Klein, M.; Jerominski, L.; Cannon, D. S.; Shabalin, A.; Docherty, A.; Williams, M.; Smith, K. R.; Keeshin, B.; Bakian, A. V.; Christensen, E.; Li, Q. S.; Camp, N. J.; Gray, D.

10.1101/195644 — genetics — Posted on 2018-08-13

1591 Stimulus-induced Gamma Power Predicts the Amplitude of the Subsequent Visual Evoked Response

van Es, M. W. J.; Schoffelen, J.-M.

10.1101/388587 — neuroscience — Posted on 2018-08-13

1592 Experimental study of Young modulus of Attacus atlas, Vespa crabro, and Libellula depressa wings

Sibilski, K. S.; Landowski, M.; Kunicka-Kowalska, Z.

10.1101/390260 — bioengineering — Posted on 2018-08-13

1593 Divergent methyl-coenzyme M reductase genes in a deep-subseafloor Archaeoglobi

Boyd, J.; Jungbluth, S.; Leu, A.; Evans, P.; Woodcroft, B.; Chadwick, G.; Orphan, V.; Amend, J.; Rappe, M.; Tyson, G.

10.1101/390617 — microbiology — Posted on 2018-08-13

1594 TranslucentID: Detecting Individuals with High Confidence in Saturated DNA SNP Mixtures

Ricke, D. O.; Watkins, J.; Fremont-Smith, P.; Boettcher, T.; Schwoebel, E.

10.1101/390146 — bioinformatics — Posted on 2018-08-13

1595 Paralogues of the PXY and ER receptor kinases enforce radial patterning in plant vascular tissue.

Wang, N.; Bagdassarian, K. S.; Doherty, R. E.; Wang, X. Y.; Kroon, J. T.; Wang, W.; Jermyn, I. H.; Turner, S. R.; Etchells, P.

10.1101/357244 — plant biology — Posted on 2018-08-13

1596 The capsule of Cryptococcus neoformans modulates phagosomal pH through its acid-base properties

DeLeon-Rodriguez, C. M.; Fu, M. S.; Corbali, M. O.; Cordero, R. J.; Casadevall, A.

10.1101/390328 — microbiology — Posted on 2018-08-13

1597 Cellular responses to proteostasis perturbations reveal non-optimal feedback in chaperone networks

Ghosh, A.; Gangadharan, A.; Das, S.; Verma, M.; Matai, L.; Dash, D.; Mapa, K.; Chakraborty, K.

10.1101/137349 — genetics — Posted on 2018-08-13

1598 Enhanced Sampling of Protein Conformational Transitions via Dynamically Optimized Collective Variables

Brotzakis, Z. F.; Parrinello, M.

10.1101/390278 — biophysics — Posted on 2018-08-13

1599 Identification of deleterious and regulatory genomic variations in known asthma loci

Neville, M. D.; Choi, J.; Lieberman, J.; Duan, Q.

10.1101/389031 — bioinformatics — Posted on 2018-08-13

1600 PGxO and PGxLOD: a reconciliation of pharmacogenomic knowledge of various provenances, enabling further comparison

Monnin, P.; Legrand, J.; Husson, G.; Ringot, P.; Tchechmedjiev, A.; Jonquet, C.; Napoli, A.; Coulet, A.

10.1101/390971 — bioinformatics — Posted on 2018-08-13

1601 Phenotypic and metabolic plasticity shapes life-history strategies under combinations of abiotic stresses

Shaar-Moshe, L.; Hayouka, R.; Roessner, U.; Peleg, Z.

10.1101/328062 — plant biology — Posted on 2018-08-13

1602 Human pointing errors suggest a flattened, task-dependent representation of space

Vuong, J.; Fitzgibbon, A.; Glennerster, A.

10.1101/390088 — neuroscience — Posted on 2018-08-13

1603 Unigene-based RNA-seq provides insights on drought stress responses in Marsdenia tenacissima

Meng, H. L.; Zhang, W.; Zhang, G. H.; Wang, J. J.; Meng, Z. G.; Long, G. Q.; Yang, S. C.

10.1101/390963 — molecular biology — Posted on 2018-08-13

1604 Improvement in Patient-Reported Sleep in Type 2 Diabetes and Prediabetes Participants Receiving a Continuous Care Intervention with Nutritional Ketosis

Siegmann, M.; Athinarayanan, S.; Hallberg, S.; McKenzie, A.; Bhanpuri, N.; Campbell, W.; McCarter, J.; Phinney, S.; Volek, J.; Van Dort, C.

10.1101/389841 — clinical trials — Posted on 2018-08-13

1605 Mitochondrial Na+ import controls oxidative phosphorylation and hypoxic redox signalling

Hernansanz-Agustin, P.; Ramos, E.; Villa-Pina, T.; Navarro, E.; Parada, E.; Moreno, L.; Izquierdo-Alvarez, A.; Oliva, T.; Cabrera-Garcia, J. D.; Cortes, A.; Tello, D.; Acin-Perez, R.; Buendia, I.; Rodriguez-Aguilera, J. C.; Navas, P.; Cogolludo, A.; Martinez-del-Pozo, A.; Egea, J.; Lopez, M. G.; Bogdanova, A.; Enriquez, J. A.; Martinez-Ruiz, A.

10.1101/385690 — biochemistry — Posted on 2018-08-13

1606 Hierarchical composition of reliable recombinase logic devices.

Guiziou, S.; Mayonove, P.; Bonnet, J.

10.1101/390823 — synthetic biology — Posted on 2018-08-13

1607 Predicting One-Year Outcome in First Episode Psychosis using Machine Learning

Leighton, S. P.; Krishnadas, R.; Chung, K.; Blair, A.; Brown, S.; Clark, S.; Sowerbutts, K.; Schwannauer, M.; Jonathan, C.; Gumley, A.

10.1101/390096 — neuroscience — Posted on 2018-08-13

1608 Anterior prefrontal cortex mediates implicit inferences

Wokke, M. E.; Ro, T.

10.1101/390427 — neuroscience — Posted on 2018-08-13

1609 A Framework for Cortical Layer Composition Analysis using Low Resolution T1 MRI Images

Shamir, I.; Tomer, O.; Baratz, Z.; Tsarfaty, G.; Faraggi, M.; Horowitz, A.; Assaf, Y.

10.1101/390112 — neuroscience — Posted on 2018-08-13

1610 Full-length de novo viral quasispecies assembly through variation graph construction

Baaijens, J.; van der Roest, B.; Koester, J.; Stougie, L.; Schoenhuth, A.

10.1101/287177 — bioinformatics — Posted on 2018-08-13

1611 Performance of convolutional neural networks for identification of bacteria in 3D microscopy datasets

Hay, E. A.; Parthasarathy, R.

10.1101/273318 — microbiology — Posted on 2018-08-13

1612 Genetic evidence that the latency III stage of Epstein-Barr Virus infection is a therapeutic target for Multiple Sclerosis

Afrasiabi, A.; Parnell, G. P.; Fewings, N.; Schibeci, S. D.; Basuki, M. A.; Chandramohan, R.; Brown, D. A.; Swaminathan, S.; McKay, F. C.; Stewart, G. J.; Booth, D. R.

10.1101/390609 — genomics — Posted on 2018-08-13

1613 Could future gene therapy prevent aging diseases?

Oliynyk, R. T.

10.1101/390773 — genomics — Posted on 2018-08-13

1614 Variants in regulatory elements of PDE4D associate with Major Mental Illness in the Finnish population

Hennah, W.; Sinha, V.; Vuoti, L.-U.; Ortega-Alonso, A.; Torniainen-Holm, M.; Therman, S.; Tuulio-Henriksson, A.; Jylhä, P.; Kaprio, J.; Hovatta, I.; Isometsä, E.; Cannon, T. D.; Lonnqvist, J.; Paunio, T.; Suvisaari, J.

10.1101/390518 — genetics — Posted on 2018-08-13

1615 Feedback between membrane tension, lipid shape and curvature in the formation of packing defects

Pinot, M.; Vanni, S.; Ambroggio, E.; Guet, D.; Goud, B.; Manneville, J.-B.

10.1101/389627 — biophysics — Posted on 2018-08-13

1616 Realistic in silico generation and augmentation of single cell RNA-seq data using Generative Adversarial Neural Networks

Bonn, S.; Machart, P.; Marouf, M.; Magruder, D. S.; Bansal, V.; Kilian, C.; Krebs, C. F.

10.1101/390153 — bioinformatics — Posted on 2018-08-13

1617 Role of sciatic nerve stiffness in surgical decision making and follow up in patients with deep gluteal syndrome

Stajic, S.; Vojvodic, A.; Carro, L. P.; Mihailovic, J.; Gasic, M.; Lukic, G.

10.1101/390120 — neuroscience — Posted on 2018-08-13

1618 Flux balance analysis predicts NADP phosphatase and NADH kinase are critical to balancing redox during xylose fermentation in Scheffersomyces stipitis

Correia, K.; Khusnutdinova, A.; Li, P. Y.; Joo, J. C.; Brown, G.; Yakunin, A. F.; Mahadevan, R.

10.1101/390401 — microbiology — Posted on 2018-08-13

1619 Strain typing and characterization of virulence genes in clinical Staphylococcus aureus isolates from Kenya

Kyanya, C.; Nyasinga, J.; Matano, D.; Oundo, V.; Wacira, S.; Sang, W.; Musila, L.

10.1101/390955 — microbiology — Posted on 2018-08-13

1620 Magic-BLAST, a accurate DNA and RNA-seq aligner for long and short reads

Boratyn, G. M.; Thierry-Mieg, J.; Thierry-Mieg, D.; Busby, B.; Madden, T. L.

10.1101/390013 — bioinformatics — Posted on 2018-08-13

1621 Development of novel lipidic particles for siRNA delivery that are highly effective after 12 months storage

Clarke, D.; Idris, A.; McMillan, N. A.

10.1101/390641 — biochemistry — Posted on 2018-08-13

1622 Rapid inference of direct interactions in large-scale ecological networks from heterogeneous microbial sequencing data

Tackmann, J.; Rodrigues, J. F. M.; von Mering, C.

10.1101/390195 — systems biology — Posted on 2018-08-13

1623 Complex genetic and epigenetic regulation deviates gene expression from a global transcriptional program

Chagoyen, M.; Poyatos, J. F.

10.1101/390419 — systems biology — Posted on 2018-08-13

1624 Cancer In The News: Bias And Quality In Media Reporting Of Cancer Research.

Amberg, A.; Saunders, D. N.

10.1101/388488 — scientific communication and education — Posted on 2018-08-13

1625 Maize EHD1 is Required for Kernel Development and Vegetative Growth through Regulating Auxin Homeostasis

Wang, Y.; Liu, W.; Wang, H.; Du, Q.; Fu, Z.; Li, W.-X.; Tang, J.

10.1101/390831 — plant biology — Posted on 2018-08-13

1626 \"Visual\" Cortices of Congenitally Blind Adults Respond to Executive Demands

Loiotile, R. E.; Bedny, M.

10.1101/390450 — neuroscience — Posted on 2018-08-13

1627 Brain-based ranking of cognitive domains to predict schizophrenia

Karrer, T. M.; Bassett, D. S.; Derntl, B.; Gruber, O.; Aleman, A.; Jardri, R.; Laird, A. R.; Fox, P.; Eickhoff, S. B.; Grisel, O.; Varoquaux, G.; Thirion, B.; Bzdok, D.

10.1101/390179 — neuroscience — Posted on 2018-08-13

1628 Multiscale dynamic mean field (MDMF) model to relate resting state brain dynamics with local cortical excitatory-inhibitory neurotransmitter homeostasis in health and disease.

Naskar, A.; Vattikonda, A.; Deco, G.; Roy, D.; Banerjee, A.

10.1101/390716 — neuroscience — Posted on 2018-08-13

1629 Concurrent neural representations of the current and forthcoming movement plans in the frontal eye field during a saccade sequence

Basu, D.; Murthy, A.

10.1101/390658 — neuroscience — Posted on 2018-08-13

1630 Reversible inactivation of different millimeter-scale regions of primate IT results in different patterns of core object recognition deficits

Rajalingham, R.; DiCarlo, J. J.

10.1101/390245 — neuroscience — Posted on 2018-08-13

1631 Sex differences in fear regulation and reward seeking behaviors in a fear-safety-reward discrimination task

Greiner, E. M.; Norris, M. R.; Müller, I.; Ng, K. H.; Sangha, S.

10.1101/390377 — neuroscience — Posted on 2018-08-13

1632 γδ T cells do not contribute to peripheral inflammatory pain

Petrovic, J.; Raymondi Silva, J.; Segal, J. P.; Marshall, A. S.; Haird, C. M.; Gilron, I.; Ghasemlou, N.

10.1101/390294 — neuroscience — Posted on 2018-08-13

1633 Connecting natural and artificial neural networks in functional brain imaging using structured sparsity

Cox, C. R.; Rogers, T. T.

10.1101/390534 — neuroscience — Posted on 2018-08-13

1634 NMDA Receptor Dysregulation by Defective Depalmitoylation in the Infantile Neuronal Ceroid Lipofuscinosis Mouse Model

Koster, K. P.; Francesconi, W.; Berton, F.; Alahmadi, S.; Srinivas, R.; Yoshii, A.

10.1101/390732 — neuroscience — Posted on 2018-08-13

1635 Real-time structural dynamics of late steps in bacterial translation initiation visualized using time-resolved cryogenic electron microscopy

Kaledhonkar, S.; Fu, Z.; Caban, K.; Li, W.; Chen, B.; Sun, M.; Gonzalez, R. L.; Frank, J.

10.1101/390674 — molecular biology — Posted on 2018-08-13

1636 Meiotic drive of female-inherited supernumerary chromosomes in a pathogenic fungus

Habig, M.; Kema, G.; Holtgrewe Stukenbrock, E.

10.1101/389650 — molecular biology — Posted on 2018-08-13

1637 Sodium chloride is an ionic checkpoint for human Th2 cell responses and shapes the atopic skin microenvironment

Matthias, J.; Maul, J.; Noster, R.; Meinl, H.; Chao, Y.-Y.; Gerstenberg, H.; Jeschke, F.; Gilles, G.; Welle, A.; Walter, J.; Nordstroem, K.; Eberhardt, K.; Renisch, D.; Donakonda, S.; Knolle, P.; Soll, D.; Grabbe, S.; Garzorz-Stark, N.; Eyerich, K.; Biedermann, T.; Baumjohann, D.; Zielinski, C. E.

10.1101/390393 — immunology — Posted on 2018-08-13

1638 A national ‘safe and just operating space’ for all in India: Past, Present and Futurea

Roy, A.; Pramanick, K.

10.1101/390138 — ecology — Posted on 2018-08-13

1639 Hippo Pathway Deregulation Drives Tissue Stiffness and Cancer Stem-like Cells in Lung Adenocarcinoma

Pankova, D.; Jiang, Y.; Vendrell, I.; Buzzelli, J.; Ryan, A. J.; Brown, C.; O'Neill, E.

10.1101/390849 — cancer biology — Posted on 2018-08-13

1640 pWGBSSimla: a profile-based whole-genome bisulphite sequencing data simulator incorporating methylation QTLs, allele-specific methylations and differentially methylated regions

Chung, R.-H.; Kang, C.-Y.

10.1101/390633 — bioinformatics — Posted on 2018-08-13

1641 A New Clustering and Nomenclature for Beta Turns Derived form High-Resolution Protein Structures

Shapovalov, M.; Vucetic, S.; Dunbrack, R. L.

10.1101/390211 — bioinformatics — Posted on 2018-08-13

1642 Co-invasion of the ladybird Harmonia axyridis and its parasites Hesperomyces virescens fungus and Parasitylenchus bifurcatus nematode to the Caucasus

Orlova-Bienkowskaja, M. J.; Spiridonov, S. E.; Butorina, N. N.; Bienkowski, A. O.

10.1101/390898 — zoology — Posted on 2018-08-13

1643 New insights of the local immune response against both fertile and infertile hydatid cysts

Hidalgo, C.; Stoore, C.; Strull, K.; Franco, C.; Correa, F.; Jimenez, M.; Hernandez, M.; Lorenzatto, K.; Ferreira, H. B.; Galanti, N.; Paredes, R.

10.1101/390989 — immunology — Posted on 2018-08-13

1644 Mycobacterium ulcerans in Mosquitoes and March flies captured from endemic areas of Northern Queensland, Australia

Singh, A.; McBride, W. J. H.; Govan, B.; Pearson, M.; Ritchie, S.

10.1101/390997 — microbiology — Posted on 2018-08-13

1645 Identification of meteorological factors affecting migration of wild birds into miyazaki and its relation to circulation of highly pathogenic avian influenza virus

Arikawa, G.; Abe, M.; Mai Thi, N.; Mitoma, S.; Notsu, K.; Nguyen, H. T.; Elhanafy, E.; Daous, H. E.; Kabali, E.; Norimine, J.; Sekiguchi, S.

10.1101/390922 — epidemiology — Posted on 2018-08-13

1646 Predicting provenance of forensic soil samples: soil DNA predicts habitat and environmental properties

Flojgaard, C.; Froslev, T. G.; Brunbjerg, A. K.; Bruun, H. H.; Moeslund, J.; Hansen, A. J.; Ejrnaes, R.

10.1101/390930 — ecology — Posted on 2018-08-13

1647 Role of the high-affinity leukotriene B4 receptor signaling in fibrosis after unilateral ureteral obstruction in mice

Kamata, M.; Amano, H.; Ito, Y.; Fujita, T.; Hosono, K.; Kamata, K.; Takeuchi, Y.; Yokomizo, T.; Shimizu, T.; Majima, M.

10.1101/390914 — pharmacology and toxicology — Posted on 2018-08-13

1648 Chemical characterization, biological assessment and molecular docking studies of essential oil of Ocimum viride

Bhagat, M.; Sangral, M.; Arya, K. A.; Rather, R. A.

10.1101/390906 — cancer biology — Posted on 2018-08-13

1649 The comparative and genetic methods for East European Unionidae taxonomy

Abdrakhmanov, A.; Anisimova, A. S.; Neretina, T. V.; Kondrashov, A. S.; Bogatov, V. V.

10.1101/390872 — zoology — Posted on 2018-08-13

1650 A model of repetitive mild brain injury without symptoms – risk for Parkinson’s disease with aging?

Kulkarni, P.; Morrison, T. R.; Cai, X.; Iriah, S.; Lange, M. S.; Kennedy, L.; Sabrick, J.; Neuroth, L.; Hoffman, G. E.; Ferris, C. F.; Praveen Kulkanri, Thomas R Morrison, Xuezhu Cai, Sade Iriah, Mary S Lange, Laprosha Kennedy, Julia S,

10.1101/390856 — neuroscience — Posted on 2018-08-13

1651 The administration of high-mobility group box 1 fragment prevents deterioration of cardiac performance by enhancement of bone marrow mesenchymal stem cell homing in the delta-sarcoglycan-deficient hamster

Kido, T.; Miyagawa, S.; Goto, T.; Tamai, K.; Ueno, T.; Toda, K.; Kuratani, T.; Sawa, Y.

10.1101/390864 — molecular biology — Posted on 2018-08-13

1652 A natural killer cell gene signature predicts melanoma patient survival

Cursons, J.; Souza Fonseca Guimaraes, F.; Anderson, A.; Foroutan, M.; Hediyeh Zadeh, S.; Behren, A.; Huntington, N. D.; Davis, M. J.

10.1101/375253 — cancer biology — Posted on 2018-08-13

1653 Large Fatty Acid-derived Aβ42 oligomers Form Ring-like Assemblies

Xi, W.; Dean, D. N.; Hansmann, U. H. E.; Rangachari, V.

10.1101/390567 — biophysics — Posted on 2018-08-12

1654 Convergent temperature representations in artificial and biological neural networks

Haesemeyer, M.; Schier, A. F.; Engert, F.

10.1101/390435 — neuroscience — Posted on 2018-08-12

1655 Nutritional and meiotic induction of heritable stress resistance states in budding yeast

Gutierrez, H.; Taghizada, B.; Meneghini, M. D.

10.1101/390286 — cell biology — Posted on 2018-08-12

1656 Cell-cell signaling elicits local Ca2+ transients in melanocyte dendrites and dendritic spine-like structures

Belote, R. L.; Simon, S. M.

10.1101/390542 — cell biology — Posted on 2018-08-12

1657 Nanoscale colocalization of NK cell activating and inhibitory receptors controls signal integration

Tomaz, D.; Pereira, P. M.; Guerra, N.; Dyson, J.; Henriques, R.; Gould, K.

10.1101/266429 — immunology — Posted on 2018-08-12

1658 The claustrum is required for reward acquisition under high cognitive demand

White, M. G.; Mu, C.; Zeng, H.; Mathur, B. N.

10.1101/390443 — neuroscience — Posted on 2018-08-12

1659 Genotype patterns in growing solid tumors

Nanda, M.; Durrett, R.

10.1101/390385 — cancer biology — Posted on 2018-08-12

1660 NRF2 activates a partial Epithelial-Mesenchymal Transition and is maximally present in a hybrid Epithelial/Mesenchymal phenotype

Bocci, F.; Tripathi, S. C.; George, J. T.; Casabar, J.; Vilchez Mercedes, S.; Wong, P. K.; Hanash, S.; Levine, H.; Onuchic, J. N.; Jolly, M. K.

10.1101/390237 — cancer biology — Posted on 2018-08-12

1661 Enhanced Sampling of Protein Conformational Transitions via Dynamically Optimized Collective Variables

Brotzakis, Z. F.; Parrinello, M.

10.1101/390278 — biophysics — Posted on 2018-08-12

1662 Structural basis and mechanism of the unfolding-induced activation of an acid response chaperone HdeA

Yu, X.-C.; Hu, Y.; Ding, J.; Li, H.; Jin, C.

10.1101/390104 — biochemistry — Posted on 2018-08-12

1663 Identification of microRNA-27a as a key regulator of cholesterol homeostasis

Khan, A. A.; Gupta, V.; Ananthamohan, K.; Arige, V.; Reddy, S.; Barthwal, M. K.; Dixit, M.; Reddy, B.; Mahapatra, N. R.

10.1101/383448 — molecular biology — Posted on 2018-08-12

1664 Rns regulates nonpilus adhesin EtpA in human Enterotoxigenic E.coli (ETEC)

Madhavan, T. P. V.

10.1101/362178 — microbiology — Posted on 2018-08-12

1665 Real-time analysis and visualization of pathogen sequence data

Neher, R.; Bedford, T.

10.1101/286187 — microbiology — Posted on 2018-08-12

1666 Epithelial control of colonisation by Streptococcus pneumoniae at the human mucosal surface

Weight, C. M.; Venturini, C.; Pojar, S.; Jochems, S.; Reine, J.; Nikolaou, E.; Solorzano, C.; Noursadeghi, M.; Brown, J. S.; Ferreira, D. M.; Heyderman, R. S.

10.1101/281576 — immunology — Posted on 2018-08-12

1667 Genomic landscape and chronological reconstruction of driver events in multiple myeloma

Maura, F.; Bolli, N.; Angelopoulos, N.; Dawson, K. J.; Leongamornlert, D.; Martincorena, I.; Mitchell, T. J.; Fullam, A.; Gonzalez, S.; Szalat, R.; Rodriguez-Martin, B.; Samur, M. K.; Glodzik, D.; Roncador, M.; Fulciniti, M.; Tai, Y. T.; Minvielle, S.; Magrangeas, F.; Moreau, P.; Corradini, P.; Anderson, K. C.; Tubio, J. M. C.; Wedge, D. C.; Gerstung, M.; Avet-Loiseau, H.; Munshi, N.; Campbell, P. J.

10.1101/388611 — cancer biology — Posted on 2018-08-12

1668 A Striatal interneuron circuit for continuous target pursuit

Kim, N.; Li, H. E.; Hughes, R. N.; Gallegos, D.; West, A.; Kim, I. H.; Yin, H. H.

10.1101/386490 — neuroscience — Posted on 2018-08-11

1669 The Network of Cancer Genes (NCG): a comprehensive catalogue of known and candidate cancer genes from cancer sequencing screens.

Kuppili Venkata, S.; Repana, D.; Nulsen, J.; Dressler, L.; Bortolomeazzi, M.; Tourna, A.; Yakovleva, A.; Palmieri, T.; Ciccarelli, F. D.

10.1101/389858 — cancer biology — Posted on 2018-08-11

1670 Exploring the effect of microdosing psychedelics on creativity in an open-label natural setting

Prochazkova, L.; Lippelt, D. P.; Colzato, L. S.; Kuchar, M.; Sjoerds, Z.; Hommel, B.

10.1101/384412 — neuroscience — Posted on 2018-08-11

1671 Expected patterns of local ancestry in a hybrid zone

Smith, J.; Payseur, B.; Novembre, J.

10.1101/389924 — evolutionary biology — Posted on 2018-08-11

1672 The soil microbial food web revisited with metatranscriptomics - predatory Myxobacteria as keystone taxon?

Petters, S.; Soellinger, A.; Bengtsson, M. M.; Urich, T.

10.1101/373365 — microbiology — Posted on 2018-08-11

1673 An epithelial-mesenchymal-amoeboid transition gene signature reveals subtypes of breast cancer progression and metastasis

Emad, A.; Ray, T.; Jensen, T. W.; Parat, M.; Natrajan, R.; Sinha, S.; Ray, P. S.

10.1101/219410 — cancer biology — Posted on 2018-08-11

1674 C. elegans exhibits coordinated oscillation in gene activation in single-cell developmental data

Hutchison, L. A. D.; Berger, B.; Kohane, I.

10.1101/114074 — developmental biology — Posted on 2018-08-11

1675 Type IV pilin post-translational modifications modulate materials properties of bacterial colonies

Zöllner, R.; Cronenberg, T.; Kouzel, N.; Welker, A.; Koomey, M.; Maier, B.

10.1101/389882 — biophysics — Posted on 2018-08-11

1676 Use of Hyperspectral Reflectance-Derived Relationship Matrices for Genomic Prediction of Grain Yield in Wheat

Krause, M. R.; Gonzalez Perez, L.; Crossa, J.; Perez-Rodriguez, P.; Montesinos-Lopez, O. A.; Singh, R.; Dreisigacker, S.; Poland, J.; Rutkoski, J.; Sorrells, M. E.; Gore, M. A.; Mondal, S.

10.1101/389825 — genomics — Posted on 2018-08-11

1677 Octave plots for visualizing diversity of microbial OTUs

Edgar, R. C.; Flyvbjerg, H.

10.1101/389833 — bioinformatics — Posted on 2018-08-11

1678 Whole genome sequencing and morphological analysis of the human-infecting schistosome emerging in Europe reveals a complex admixture between Schistosoma haematobium and Schistosoma bovis parasites.

Kincaid-Smith, J.; Tracey, A.; de Carvalo Augusto, R.; Bulla, I.; Holroyd, N.; Rognon, A.; Rey, O.; Chaparro, C.; Oleaga, A.; Mas Coma, S.; Allienne, J.-F.; Grunau, C.; Berriman, M.; Boissier, J.; Toulza, E.

10.1101/387969 — genomics — Posted on 2018-08-11

1679 Large-scale whole-genome sequencing of three diverse Asian populations in Singapore

Wu, D.; Dou, J.; Chai, X.; Bellis, C.; Wilm, A.; Shih, C. C.; Soon, W. W. J.; Bertin, N.; Khor, C. C.; DeGiorgio, M.; Dominguez, S. M. D.; Tan, P.; Shabbir, A.; Moh, A.; Tan, E.-K.; Foo, J. N.; Tan Tock Seng Hospital Healthy Control Workgroup, ; Foo, R. S.; Lam, C. S. P.; Richards, A. M.; Cheng, C.-Y.; Aung, T.; Wong, T. Y.; Liu, J.; Wang, C.; The SG10K Consortium,

10.1101/390070 — genetics — Posted on 2018-08-11

1680 Expected patterns of local ancestry in a hybrid zone

Smith, J.; Payseur, B.; Novembre, J.

10.1101/389924 — evolutionary biology — Posted on 2018-08-11

1681 Preliminary prediction of the potential distribution and consequences of Haemaphysalis longicornis (Ixodida: Ixodidae) in the United States and North America, using a simple rule-based climate envelope model

Magori, K.

10.1101/389940 — ecology — Posted on 2018-08-11

1682 Hierarchical Patient-centric Caregiver Network Method for Clinical Outcomes Study

Park, Y.; Karampourniotis, P.; Sylla, I.; Das, A. K.

10.1101/388066 — bioinformatics — Posted on 2018-08-11

1683 Epiretinal stimulation with local returns enhances selectivity at cellular resolution

Fan, V. H.; Grosberg, L. E.; Madugula, S. S.; Hottowy, P.; Dabrowski, W.; Sher, A.; Litke, A. M.; Chichilnisky, E. J.

10.1101/275958 — neuroscience — Posted on 2018-08-11

1684 Quenching a swarm: Effect of light exposure on suppression of collective motility in swarming Serratia marcescens

Patteson, A. E.; Arratia, P.; Gopinath, A.

10.1101/331801 — biophysics — Posted on 2018-08-11

1685 Schizophrenia-associated genomic copy number variants and subcortical brain volumes in the UK Biobank

Warland, A.; Kendall, K.; Rees, E.; Kirov, G.; Caseras, X.

10.1101/374678 — neuroscience — Posted on 2018-08-11

1686 The Network of Cancer Genes (NCG): a comprehensive catalogue of known and candidate cancer genes from cancer sequencing screens.

Ciccarelli, F. D.; Kuppili Venkata, S.; Repana, D.; Nulsen, J.; Dressler, L.; Bortolomeazzi, M.; Tourna, A.; Yakovleva, A.; Palmieri, T.

10.1101/389858 — cancer biology — Posted on 2018-08-11

1687 Inactivation of medial frontal cortex changes risk preference

Stuphorn, V.; Chen, X.

10.1101/390021 — neuroscience — Posted on 2018-08-10

1688 SNP-ChIP: A versatile and tag-free method to quantify changes in protein binding across the genome

Vale-Silva, L. A.; Markowitz, T. E.; Hochwagen, A.

10.1101/390005 — genomics — Posted on 2018-08-10

1689 Reconstructing B cell receptor sequences from short-read single cell RNA-sequencing with BRAPeS

Afik, S.; Yosef, N.

10.1101/389999 — bioinformatics — Posted on 2018-08-10

1690 Phosphatidylinositol 3,5-Bisphosphate Regulates Yeast Vacuole Fusion at the Transition between trans-SNARE Complex Formation and Hemifusion

Miner, G. E.; Sullivan, K. D.; Guo, A.; Jones, B. C.; Starr, M. L.; Fratti, R. A.

10.1101/390062 — biochemistry — Posted on 2018-08-10

1691 Resting state functional connectivity patterns associated with pharmacological treatment resistance in temporal lobe epilepsy

Pressl, C.; Brandner, P.; Schaffelhofer, S.; Blackmon, K.; Dugan, P.; Holmes, M.; Thesen, T.; Kuzniecky, R.; Devinsky, O.; Freiwald, W. A.

10.1101/382523 — neuroscience — Posted on 2018-08-10

1692 Latent Structure of Risk Perception

Pabon, E.; MacKillop, J.; Palmer, A.; de Wit, H.

10.1101/389890 — neuroscience — Posted on 2018-08-10

1693 Complete decoupling of bacterial growth from biopolymer production through proteolytic control of enzyme levels

Durante-Rodriguez, G.; de Lorenzo, V.; Nikel, P. I.

10.1101/389809 — synthetic biology — Posted on 2018-08-10

1694 Mitochondrial hypoxic stress induces widespread RNA editing by APOBEC3G in lymphocytes

Sharma, S.; Wang, J.; Portwood, S.; Cortes-Gomez, E.; Maguire, O.; Basse, P. H.; Wang, E.; Baysal, B. E.

10.1101/389791 — molecular biology — Posted on 2018-08-10

1695 RNAmountAlign: efficient software for local, global, semiglobal pairwise and multiple RNA sequence/structure alignment

Bayegan, A. H.; Clote, P.

10.1101/389312 — bioinformatics — Posted on 2018-08-10

1696 Inference of phenotype-relevant transcriptional regulatory networks elucidates cancer type-specific regulatory mechanisms in a pan-cancer study

Emad, A.; Sinha, S.

10.1101/389734 — bioinformatics — Posted on 2018-08-10

1697 Deep learning for high-throughput quantification of oligodendrocyte ensheathment: a UNet architecture to extract multiple morphological parameters from individual cells

Xu, Y. K. T.; Chitsaz, D.; Brown, R. A.; Cui, Q. L.; Dabarno, M. A.; Antel, J. P.; Kennedy, T. E.

10.1101/389932 — bioinformatics — Posted on 2018-08-10

1698 Hierarchical Complexity of the Adult Human Structural Connectome

Smith, K.; Bastin, M. E.; Cox, S. R.; Valdes-Hernandez, M. C.; Wiseman, S.; Escudero, J.; Sudlow, C.

10.1101/389569 — systems biology — Posted on 2018-08-10

1699 Compartmentalized nonsense-mediated mRNA decay regulates synaptic plasticity and cognitive function via GluR1 signaling

Notaras, M.; Allen, M.; Longo, F.; Volk, N.; Toth, M.; Jeon, N. L.; Klann, E.; Colak, D.

10.1101/389585 — neuroscience — Posted on 2018-08-10

1700 IDH1R132H acts as a tumor suppressor in glioma via epigenetic upregulation of the DNA damage response

Nunez, F. J.; Mendez, F. M.; Kadilaya, P.; Alghamri, M. S.; Savelieff, M.; Koschmann, C.; Calinescu, A.-A.; Kamran, N.; Patel, R.; Guo, M. Z.; Carney, S.; Garcia-Fabiani, M. B.; Haase, S.; Edwards, M.; Ljungman, M.; Qin, T.; Sartor, M.; Tagett, R.; Venneti, S.; Brosnan-Cashman, J.; Meeker, A.; Gorbunova, V.; Zhao, L.; Kramer, D.; Zhang, L.; Lyssiotis, C. A.; Jones, L.; Herting, C.; Ross, J.; Hambardzumyan, D.; Hervey-Jumper, S.; Figueroa, M. E.; Lowenstein, P. R.; Castro, M. G.

10.1101/389817 — cancer biology — Posted on 2018-08-10

1701 Impaired expected value computations in schizophrenia are associated with a reduced ability to integrate reward probability and magnitude of recent outcomes.

Hernaus, D.; Frank, M. J.; Brown, E. C.; Brown, J. K.; Gold, J. M.; Waltz, J. A.

10.1101/389551 — neuroscience — Posted on 2018-08-10

1702 Reactivation of time cell sequences in the hippocampus

Belchior, H. A.; Pavao, R.; Furtunato, A. M. B.; Eichenbaum, H.; Tort, A. B. L.

10.1101/389874 — neuroscience — Posted on 2018-08-10

1703 Evidence against the microbicidal action of neutrophil extracellular traps (NETs)

Semplici, F.; Segal, A. W.

10.1101/389593 — immunology — Posted on 2018-08-10

1704 Hydraulic control of embryo size, tissue shape and cell fate

Chan, C. J.; Costanzo, M.; Ruiz-Herrero, T.; Monke, G.; Petrie, R.; Mahadevan, L.; Hiiragi, T.

10.1101/389619 — developmental biology — Posted on 2018-08-10

1705 Functional proteomic atlas of HIV-infection inprimary human CD4+ T cells

Naamati, A.; Williamson, J. C.; Greenwood, E. J.; Marelli, S.; Lehner, P. J.; Matheson, N. J.

10.1101/389346 — microbiology — Posted on 2018-08-10

1706 Software tools for automated transmission electron microscopy

Schorb, M.; Haberbosch, I.; Hagen, W.; Schwab, Y.; Mastronarde, D.

10.1101/389502 — cell biology — Posted on 2018-08-10

1707 Theta oscillations show impaired interference detection in the elderly during selective memory retrieval

Ferreira, C. S.; Maraver, M. J.; Hanslmayr, S.; Bajo, M. T.

10.1101/388595 — neuroscience — Posted on 2018-08-10

1708 Positive Selection and Adaptation of Novel Inner Ear Genes in the Mammalian Lineage

Pisciottano, F.; Cinalli, A. R.; Stopiello, M.; Castagna, V. C.; Elgoyhen, B. A.; Rubinstein, M.; Gomez-Casati, M. E.; Franchini, L. F.

10.1101/388496 — evolutionary biology — Posted on 2018-08-10

1709 Atomic-level characterization of conformational transition and substrate binding of xCT transporter

Sharma, M.

10.1101/389643 — biophysics — Posted on 2018-08-10

1710 The C-terminal tail of the bacterial translocation ATPase SecA modulates its activity

Jamshad, M.; Knowles, T.; White, S.; Ward, D.; Mohammed, F.; Rahman, K. F.; Hughes, G. W.; Kramer, G.; Bukau, B.; Huber, D.

10.1101/389460 — biochemistry — Posted on 2018-08-10

1711 Spatiotemporal Dynamics of Molecular Pathology in Amyotrophic Lateral Sclerosis

Maniatis, S.; Aijo, T.; Vickovic, S.; Braine, C.; Kang, K.; Mollbrink, A.; Andrusivova, Z.; Saarenpaa, S.; Saiz-Castro, G.; Cuevas, M.; Watters, A.; Lundeberg, J.; Bonneau, R.; Phatnani, H.

10.1101/389270 — neuroscience — Posted on 2018-08-10

1712 ULK-mediated phosphorylation of ATG16L1 promotes xenophagy, but destabilizes the ATG16L1 Crohn’s mutant

Alsaadi, R. M.; Losier, T. T.; Tian, W.; Guo, Z.; Russell, R. C.

10.1101/387563 — molecular biology — Posted on 2018-08-10

1713 Mapping Transgene Insertion Sites Reveals Complex Interactions Between Mouse Transgenes And Neighboring Endogenous Genes

Laboulaye, M. A.; Duan, X.; Qiao, M.; Whitney, I. E.; Sanes, J.

10.1101/389676 — genetics — Posted on 2018-08-10

1714 The spectral identity of foveal cones is preserved in hue perception

Schmidt, B. P.; Boehm, A. E.; Foote, K. G.; Roorda, A.

10.1101/317750 — neuroscience — Posted on 2018-08-10

1715 Whole blood transcriptome analysis reveals footprints of cattle adaptation to sub-arctic conditions

Pokharel, K.; Weldenegodguad, M.; Popov, R.; Honkatukia, M.; Huuki, H.; Lindeberg, H.; Peippo, J.; Reilas, T.; Zarovnyaev, S.; Kantanen, J.

10.1101/379925 — genetics — Posted on 2018-08-10

1716 Delayed memory deficits in males and females long after subchronic immune challenge

Tchessalova, D.; Tronson, N. C.

10.1101/379339 — animal behavior and cognition — Posted on 2018-08-10

1717 Kappa opioid receptor modulation on GABAergic inputs onto ventral periaqueductal gray dopamine neurons

Kash, T.; Li, C.

10.1101/389536 — neuroscience — Posted on 2018-08-10

1718 Spatial and temporal locomotor learning in mouse cerebellum

Darmohray, D.; Jacobs, J.; Marques, H. G.; Carey, M. R.

10.1101/389965 — neuroscience — Posted on 2018-08-10

1719 Joint single-cell DNA accessibility and protein epitope profiling reveals environmental regulation of epigenomic heterogeneity

Chen, X.; Litzenburger, U.; Wei, Y.; Schep, A. N.; LaGory, E. L.; Choudhry, H.; Giaccia, A. J.; Greenleaf, W. J.; Chang, H.

10.1101/310359 — genomics — Posted on 2018-08-10

1720 Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity reveals structural factors responsible for differences in amino acid preferences between peptide-based substrates and covalent inhibitors.

de Vries, L. E.; Sanchez, M. I.; Groborz, K.; Kuppens, L.; Poreba, M.; Lehmann, C.; Yuan, F.; Arastu-Kapur, S.; Horn, M.; Mares, M.; Bogyo, M.; Drag, M.; Deu, E.

10.1101/246124 — biochemistry — Posted on 2018-08-10

1721 Evaluation of nutrient stoichiometric relationships amongst ecosystem compartments of a subtropical treatment wetland. Fine-scale analysis of wetland nutrient stoichiometry.

Julian, P.; Gerber, S.; Bhomia, R.; King, J.; Osborne, T. Z.; Wright, A. L.; Power, M.

10.1101/220186 — ecology — Posted on 2018-08-10

1722 In-field metagenome and 16S rRNA gene amplicon nanopore sequencing robustly characterize glacier microbiota

Edwards, A.; Debbonaire, A. R.; Nicholls, S. M.; Rassner, S. M.; Sattler, B.; Cook, J. M.; Davy, T.; Mur, L. A.; Hodson, A. J.

10.1101/073965 — microbiology — Posted on 2018-08-10

1723 Exploration and generalization in vast spaces

Wu, C. M.; Schulz, E.; Speekenbrink, M.; Nelson, J. D.; Meder, B.

10.1101/171371 — animal behavior and cognition — Posted on 2018-08-10

1724 AlleleHMM: a data-driven method to identify allele-specific differences in distributed functional genomic marks

Chou, S.-P.; Danko, C. G.

10.1101/389262 — bioinformatics — Posted on 2018-08-10

1725 Fluorescence-Based Detection of Fusion State on a Cryo-EM Grid using Correlated Cryo-Fluorescence and Cryo-Electron Microscopy

Metskas, L. A.; Briggs, J. A. G.

10.1101/388579 — biophysics — Posted on 2018-08-10

1726 Protein interaction energy landscapes are shaped by functional and also non-functional partners

Schweke, H.; Mucchielli, M.-H.; Sacquin-Mora, S.; Bei, W.; Lopes, A.

10.1101/298174 — bioinformatics — Posted on 2018-08-10

1727 Influence of temperature on the development, reproduction and regeneration in the flatworm model organism Macrostomum lignano

Wudarski, J.; Ustyantsev, K.; Glazenburg, L.; Berezikov, E.

10.1101/389478 — zoology — Posted on 2018-08-10

1728 Microbial Diversity in a Military Impacted Lagoon (Vieques, Puerto Rico) as Revealed by Metagenomics

Davila-Santiago, L.; DeLeon-Rodriguez, N.; LaSanta-Pagan, K.; Hatt, J.; Kurt, Z.; Massol-Deya, A.; Konstantinidis, K. T.

10.1101/389379 — microbiology — Posted on 2018-08-10

1729 Common ancestry of heterodimerizing TALE homeobox transcription factors across Metazoa and Archaeplastida

Joo, S.; Wang, M. H.; Lui, G.; Lee, J.; Barnas, A.; Kim, E.; Sudek, S.; Worden, A. Z.; Lee, J.-H.

10.1101/389700 — evolutionary biology — Posted on 2018-08-10

1730 Qualitative modeling of signaling networks in replicative senescence by selecting optimal node and arc sets

Sakellaropoulos, T.; Binenbaum, I.; Lefaki, M.; Chatziioannou, A.; Chondrogianni, N.; Alexopoulos, L. G.

10.1101/389692 — systems biology — Posted on 2018-08-10

1731 Ubiquity of collective irregular dynamics in balanced networks of spiking neurons

Ullner, E.; Politi, A.; Torcini, A.

10.1101/389452 — neuroscience — Posted on 2018-08-10

1732 Collective irregular dynamics in balanced networks of leaky integrate-and-fire neurons

Politi, A.; Ullner, E.; Torcini, A.

10.1101/389486 — neuroscience — Posted on 2018-08-10

1733 Unity and diversity in working memory load: Evidence for the separability of the executive functions updating and inhibition using machine learning

Krumpe, T.; Scharinger, C.; Rosenstiel, W.; Gerjets, P.; Spueler, M.

10.1101/389395 — neuroscience — Posted on 2018-08-10

1734 Killing from the inside: Intracellular role of T3SS in the fate of Pseudomonas aeruginosa within macrophages revealed by mgtC and oprF mutants

Blanc-Potard, A.-B.; Garai, P.; Berry, L.; Moussouni, M.; Bleves, S.

10.1101/389718 — microbiology — Posted on 2018-08-10

1735 Cathelicidin senses enteric pathogen Salmonella typhimurium/LPS for colonic chemokine generation: a new innate immune role for a host defense peptide

Cobo, E. R.; Holani, R.; Lopes, F.; Blyth, G. A. D.; Jijon, H.; McKay, D. M.; Hollenberg, M. D.

10.1101/389726 — immunology — Posted on 2018-08-10

1736 High-quality SNPs from genic regions highlight introgression patterns among European white oaks (Quercus petraea and Q. robur).

Lang, T.; Abadie, P.; Leger, V.; Decourcelle, T.; Frigerio, J.-M.; Burban, C.; Bodenes, C.; Guichoux, E.; Le Provost, G.; Robin, C.; Tani, N.; Leger, P.; Lepoittevin, C.; El Mujtar, V. A.; Hubert, F.; Tibbits, J.; Paiva, J.; Franc, A.; Raspail, F.; Mariette, S.; Reviron, M.-P.; Plomion, C.; Kremer, A.; Desprez-Loustau, M.-L.; Garnier-Gere, P.

10.1101/388447 — evolutionary biology — Posted on 2018-08-10

1737 Rapid and efficient C-terminal labeling of nanobodies for DNA-PAINT

Fabricius, V.; Lefebre, J.; Geertsema, H.; Marino, S. F.; Ewers, H.

10.1101/389445 — biophysics — Posted on 2018-08-10

1738 The Role of Gdf5 Regulatory Regions on Development of Hip Morphology and Susceptibility to Osteoarthritis and Dislocation

Capellini, T. D.; Kiapour, A. M.; Cao, J.; Young, M.

10.1101/389684 — genetics — Posted on 2018-08-10

1739 GRaphical footprint based Alignment-Free method (GRAFree) for reconstructing evolutionary Traits in Large-Scale Genomic Features

Mahapatra, A.; Mukherjee, J.

10.1101/389403 — evolutionary biology — Posted on 2018-08-10

1740 Hexokinase: A central player in the synergism of high-intensity intermittent exercise and every-other-day intermittent fasting regimen on energy metabolism adaptations

Real-Hohn, A.; Navegantes, C.; Ramos, K.; Ramos-Filho, D.; Cahue, F.; Galina, A.; Salerno, V.

10.1101/389668 — biochemistry — Posted on 2018-08-10

1741 Loss of Frrs1l disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities

Stewart, M.; Lau, P. Y.; Banks, G.; Bains, R. S.; Castroflorio, E.; Oliver, P. L.; Dixon, C. L.; Kruer, M. C.; Kullmann, D. M.; Acevedo-Arozena, A.; Wells, S. E.; Corrochano, S.; Nolan, P.

10.1101/388561 — neuroscience — Posted on 2018-08-10

1742 Development of whole-porcine monoclonal antibodies with potent neutralization activity against classical swine fever virus (CSFV) from single B cells

Dong, H.; Lv, D.; Su, A.; Ma, L.; Dong, J.; Guo, N.; Ren, L.; Jiao, H.; Pang, D.; Ouyang, H.

10.1101/389361 — molecular biology — Posted on 2018-08-10

1743 Replication of the diathesis-stress model for depression in Generation Scotland.

Arnau-Soler, A.; Adams, M.; Clarke, T.-K.; MacIntyre, D.; Milburn, K.; Navrady, L.; Generation Scotland, ; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, ; Hayward, C.; McIntosh, A.; Thomson, P.

10.1101/389494 — genomics — Posted on 2018-08-10

1744 Choosing the right label for single-molecule tracking in live bacteria: Side-by-side comparison of photoactivatable fluorescent protein and Halo tag dyes

Banaz, N.; Makela, J.; Uphoff, S.

10.1101/381665 — biophysics — Posted on 2018-08-10

1745 Hydrodynamics of linear acceleration in bluegill sunfish Lepomis macrochirus

Wise, T. N.; Schwalbe, M. A. B.; Tytell, E. D.

10.1101/386342 — biophysics — Posted on 2018-08-10

1746 deGSM: memory scalable construction of large scale de Bruijn Graph

Guo, H.; Fu, Y.; Gao, Y.; Li, J.; Wang, Y.; Liu, B.

10.1101/388454 — bioinformatics — Posted on 2018-08-10

1747 Reaction times and other skewed distributions: problems with the mean and the median

Rousselet, G. A.; Wilcox, R. R.

10.1101/383935 — neuroscience — Posted on 2018-08-10

1748 A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity

Bardelli, M.; Frontzek, K.; Simonelli, L.; Hornemann, S.; Pedotti, M.; Mazzola, F.; Carta, M.; Eckhardt, V.; D'Antuono, R.; Virgilio, T.; Gonzales, S. F.; Aguzzi, A.; Varani, L.

10.1101/386763 — molecular biology — Posted on 2018-08-10

1749 Identification and Ranking of Recurrent Neo-Epitopes in Cancer

Blanc, E.; Holtgrewe, M.; Dhamodaran, A.; Messerschmidt, C.; Willimsky, G.; Blankenstein, T.; Beule, D.

10.1101/389437 — genomics — Posted on 2018-08-10

1750 Multi-target visual search organisation across the lifespan: Cancellation task performance in a large and demographically stratified sample of healthy adults

Benjamins, J. S.; Dalmaijer, E. S.; Ten Brink, A. F.; Nijboer, T. C. W.; Van der Stigchel, S.

10.1101/307520 — neuroscience — Posted on 2018-08-10

1751 Measurements of the self-assembly kinetics of individual viral capsids around their RNA genome

Garmann, R. F.; Goldfain, A. M.; Manoharan, V. N.

10.1101/265330 — biophysics — Posted on 2018-08-10

1752 Assessing sub-cellular resolution in spatial proteomics experiments

Gatto, L.; Breckels, L. M.; Lilley, K. S.

10.1101/377630 — bioinformatics — Posted on 2018-08-10

1753 Comprehensive profiling of the fission yeast transcription start site activity during stress and media response

Thodberg, M.; Thieffry, A.; Bornholdt, J.; Boyd, M.; Holmberg, C.; Azad, A.; Workman, C. T.; Chen, Y.; Ekwall, K.; Nielsen, O.; Sandelin, A.

10.1101/281642 — genomics — Posted on 2018-08-10

1754 Ordino: a visual analysis tool for ranking and exploring genes, cell lines, and tissue samples

Streit, M.; Gratzl, S.; Stitz, H.; Wernitznig, A.; Zichner, T.; Haslinger, C.

10.1101/277848 — bioinformatics — Posted on 2018-08-10

1755 Delayed start of first-time breeding and non-breeders surplus in the Western Siberian population of the European Pied Flycatcher

Grinkov, V. G.; Sternberg, H.

10.1101/387829 — zoology — Posted on 2018-08-10

1756 Representing Multiple Observed Actions in the Motor System

Cracco, E.; Keysers, C.; Clauwaert, A.; Brass, M.

10.1101/387704 — neuroscience — Posted on 2018-08-10

1757 Reconstructing the history of polygenic scores using coalescent trees

Edge, M.; Coop, G.

10.1101/389221 — evolutionary biology — Posted on 2018-08-10

1758 MIC-MAC: High-throughput analysis of three-dimensional microglia morphology in mammalian brains

Salamanca, L.; Mechawar, N.; Murai, K. K.; Balling, R.; Bouvier, D. S.; Skupin, A.

10.1101/388397 — neuroscience — Posted on 2018-08-10

1759 A Biologically Plausible Mechanism to Learn Clusters of Neural Activity

Loback, A. R.; Berry, M. J.

10.1101/389155 — neuroscience — Posted on 2018-08-10

1760 Interleukin-1 receptor antagonist mediates type I interferon-driven susceptibility to Mycobacterium tuberculosis

Ji, D. X.; Chen, K. J.; Mukaida, N.; Kramnik, I.; Darwin, K. H.; Vance, R. E.

10.1101/389288 — immunology — Posted on 2018-08-10

1761 Discovery of allele-specific protein-RNA interactions in human transcriptomes

Bahrami-Samani, E.; Xing, Y.

10.1101/389205 — bioinformatics — Posted on 2018-08-10

1762 Domain-general enhancements of metacognitive ability through adaptive training

Carpenter, J.; Sherman, M. T.; Kievit, R. A.; Seth, A.; Lau, H.; Fleming, S.

10.1101/388058 — animal behavior and cognition — Posted on 2018-08-10

1763 A Phantom System Designed to Assess the Effects of Membrane Lipids on Water Proton Relaxation

Shtangel, O.; Mezer, A.

10.1101/387845 — neuroscience — Posted on 2018-08-09

1764 Population sequencing reveals clonal diversity and ancestral inbreeding in the grapevine cultivar Chardonnay

Roach, M. J.; Johnson, D.; Bohlmann, J.; van Vuuren, H.; Jones, S.; Pretorius, I.; Schmidt, S. A.; Borneman, A. R.

10.1101/389197 — genomics — Posted on 2018-08-09

1765 A Chemically-triggered Transition from Conflict to Cooperation in Burying Beetles

Chen, B.-F.; Liu, M.; Rubenstein, D. R.; Sun, S.-J.; Liu, J.-N.; Lin, Y.-H.; Shen, S.-F.

10.1101/389163 — evolutionary biology — Posted on 2018-08-09

1766 Allele frequency dynamics in a pedigreed natural population

Chen, N.; Juric, I.; Cosgrove, E. J.; Bowman, R.; Fitzpatrick, J. W.; Schoech, S. J.; Clark, A. G.; Coop, G.

10.1101/388710 — evolutionary biology — Posted on 2018-08-09

1767 deGSM: memory scalable construction of large scale de Bruijn Graph

Guo, H.; Fu, Y.; Gao, Y.; Li, J.; Wang, Y.; Liu, B.

10.1101/388454 — bioinformatics — Posted on 2018-08-09

1768 Structure-activity relationship of flavin analogs that target the FMN riboswitch

Vicens, Q.; Mondragon, E.; Reyes, F. E.; Coish, P.; Aristoff, P.; Bermann, J.; Kaur, H.; Wells, K. W.; Wickens, P.; Wilson, J.; Gadwood, R. C.; Schostarez, H. J.; Suto, R. K.; Blount, K. F.; Batey, R. T.

10.1101/389148 — biochemistry — Posted on 2018-08-09

1769 Spatiotemporal Dynamics of Molecular Pathology in Amyotrophic Lateral Sclerosis

Maniatis, S.; Aijo, T.; Vickovic, S.; Braine, C.; Kang, K.; Mollbrink, A.; Andrusivova, Z.; Saarenpaa, S.; Saiz-Castro, G.; Cuevas, M.; Watters, A.; Lundeberg, J.; Bonneau, R.; Phatnani, H.

10.1101/389270 — neuroscience — Posted on 2018-08-09

1770 Aurora A depletion reveals centrosome-independent polarization mechanism in C. elegans

Klinkert, K.; Levernier, N.; Gross, P.; Gentili, C.; von Tobel, L.; Pierron, M.; Busso, C.; Herrman, S.; Grill, S. W.; Kruse, K.; Gonczy, P.

10.1101/388918 — cell biology — Posted on 2018-08-09

1771 One read per cell per gene is optimal for single-cell RNA-Seq

Zhang, M. J.; Ntranos, V.; Tse, D.

10.1101/389296 — bioinformatics — Posted on 2018-08-09

1772 Antibody responses to Zika virus protein in pregnant and non-pregnant macaques

Heffron, A. S.; Mohr, E. L.; Baker, D.; Haj, A. K.; Buechler, C. R.; Bailey, A.; Dudley, D.; Newman, C. M.; Mohns, M. S.; Koenig, M.; Breitbach, M. E.; Rasheed, M.; Stewart, L. M.; Eickhoff, J. C.; Pinapati, R. S.; Beckman, E.; Li, H.; Patel, J. J.; Tan, J. C.; O'Connor, D. H.

10.1101/352880 — microbiology — Posted on 2018-08-09

1773 Lateral gene transfer shapes the distribution of RuBisCO among Candidate Phyla Radiation bacteria and DPANN archaea

Jaffe, A. L.; Castelle, C. J.; Dupont, C. L.; Banfield, J. F.

10.1101/386292 — microbiology — Posted on 2018-08-09

1774 Toward deciphering developmental patterning with deep neural network

Shen, J.; Petkova, M. D.; Liu, F.; Tang, C.

10.1101/374439 — developmental biology — Posted on 2018-08-09

1775 Domain Insertion Permissibility is a Measure of Engineerable Allostery in Ion Channels

Coyote-Maestas, W.; He, Y.; Myers, C. L.; Schmidt, D.

10.1101/334672 — biochemistry — Posted on 2018-08-09

1776 The Landscape of Enteric Pathogen Exposure of Young Children in Public Domains of Low-Income, Urban Kenya: The Influence of Exposure Pathway and Spatial Range of Play on Multi-Pathogen Exposure Risks

Medgyesi, D. N.; Sewell, D.; Senesac, R.; Cumming, O.; Mumma, J.; Baker, K. K.

10.1101/388140 — microbiology — Posted on 2018-08-09

1777 Resolving the individual contribution of key microbial populations to enhanced biological phosphorus removal with Raman-FISH

Fernando, E. Y.; McIlroy, S. J.; Nierychlo, M.; Herbst, F.-A.; Schmid, M. C.; Wagner, M.; Nielsen, J. L.; Nielsen, P. H.

10.1101/387795 — ecology — Posted on 2018-08-09

1778 PCH-2TRIP13 regulates spindle checkpoint strength

Defachelles, L.; Russo, A. E.; Nelson, C. R.; Bhalla, N.

10.1101/389080 — cell biology — Posted on 2018-08-09

1779 HIF-2α drives an intrinsic vulnerability to ferroptosis in clear cell renal cell carcinoma

Zou, Y.; Palte, M. J.; Deik, A. A.; Li, H.; Eaton, J. K.; Wang, W.; Tseng, Y.-Y.; Deasy, R.; Alimova, M.; Dancik, V.; Leshchiner, E. S.; Viswanathan, V. S.; Signoretti, S.; Choueiri, T. K.; Boehm, J. S.; Wagner, B. K.; Doench, J.; Clish, C. B.; Clemons, P. A.; Schreiber, S. L.

10.1101/388041 — cancer biology — Posted on 2018-08-09

1780 Persistent activity in primate auditory cortex evoked by sensory stimulation

Cooke, J. E.; Lee, J. J.; Bartlett, E. L.; Wang, X.; Bendor, D.

10.1101/387837 — neuroscience — Posted on 2018-08-09

1781 Target-specific precision of CRISPR-mediated genome editing

Chakrabarti, A. M.; Henser-Brownhill, T.; Monserrat, J.; Poetsch, A. R.; Luscombe, N. M.; Scaffidi, P.

10.1101/387027 — molecular biology — Posted on 2018-08-09

1782 Propionic acid enhances the virulence of Crohn’s disease-associated adherent-invasive Escherichia coli

Ormsby, M. J.; Johnson, S. A.; Meikle, L. M.; Goldstone, R. J.; McIntosh, A.; Wessel, H. M.; Hulme, H. E.; McConnachie, C. C.; Connolly, J. P.; Roe, A. J.; Fitzgerald, E.; Gerasimidis, K.; Morrison, D.; Smith, D. G.; Wall, D. M.

10.1101/387647 — microbiology — Posted on 2018-08-09

1783 HIV-Attributed Causes of Death in the Medical Ward at the Chris Hani Baragwanath Hospital, South Africa

Black, A.; Sitas, F.; Chibrawara, T.; Gill, Z.; Kubanje, M.; Williams, B. G.

10.1101/388462 — epidemiology — Posted on 2018-08-09

1784 A specialized MreB-dependent complex mediates the formation of stalk-specific peptidoglycan in Caulobacter crescentus

Billini, M.; Biboy, J.; Kühn, J.; Vollmer, W.; Thanbichler, M.

10.1101/389114 — cell biology — Posted on 2018-08-09

1785 Tree Shape-based approaches for the Comparative study of Cophylogeny

Avino, M.; Ng, G. T.; He, Y.; Renaud, M. S.; Jones, B. R.; Poon, A. F.

10.1101/388116 — evolutionary biology — Posted on 2018-08-09

1786 Real-time analysis of the diphtheria outbreak in forcibly displaced Myanmar nationals in Bangladesh

Finger, F.; Funk, S.; White, K.; Siddiqui, R.; Edmunds, W. J.; Kucharski, A. J.

10.1101/388645 — epidemiology — Posted on 2018-08-09

1787 Correlates of cannabinoid concentrations, real-world driving, and driving-related skills

Johnson, M. B.

10.1101/387936 — epidemiology — Posted on 2018-08-09

1788 Personal clinical history predicts antibiotic resistance in urinary tract infections

Yelin, I.; Snitser, O.; Novich, G.; Katz, R.; Tal, O.; Parizade, M.; Chodick, G.; Koren, G.; Shalev, V.; Kishony, R.

10.1101/384842 — epidemiology — Posted on 2018-08-09

1789 The origins and relatedness structure of mixed infections vary with local prevalence of P. falciparum malaria

Zhu, S. J.; Hendry, J. A.; Almagro-Garcia, J.; Pearson, R. D.; Amato, R.; Miles, A.; Weiss, D. J.; Lucas, T. C. D.; Nguyen, M.; Gething, P. W.; Kwiatkowski, D.; McVean, G.; Pf3k Project,

10.1101/387266 — epidemiology — Posted on 2018-08-09

1790 Stimulus-induced Gamma Power Predicts the Amplitude of the Subsequent Visual Evoked Response

van Es, M. W. J.; Schoffelen, J.-M.

10.1101/388587 — neuroscience — Posted on 2018-08-09

1791 Dragotcytosis: Elucidation of the Mechanism for Cryptococcus neoformans Macrophage-to-Macrophage Transfer

Dragotakes, Q.; Fu, M. S.; Casadevall, A.

10.1101/387688 — microbiology — Posted on 2018-08-09

1792 Identification of Key Differentially Expressed MicroRNAs in Cancer Patients Through Pan-cancer Analysis

Hu, Y.; Dingerdissen, H.; Gupta, S.; Kahsay, R.; Shanker, V.; Wan, Q.; Yan, C.; Mazumder, R.

10.1101/388892 — bioinformatics — Posted on 2018-08-09

1793 Sostdc1 regulates natural killer cell maturation and cytotoxicity

Millan, A. J.; Elizaldi, S. R.; Lee, E. M.; Aceves, J. O.; Murugesh, D. K.; Loots, G. G.; Manilay, J. O.

10.1101/387225 — immunology — Posted on 2018-08-09

1794 Powerful and interpretable behavioural features for quantitative phenotyping of C. elegans

Javer, A.; Ripoll-Sanchez, L.; Brown, A. E.

10.1101/389023 — animal behavior and cognition — Posted on 2018-08-09

1795 Functional Interpretation of Genetic Variants Using Deep Learning Predicts Impact on Epigenome

Hoffman, G. E.; Schadt, E. E.; Roussos, P.

10.1101/389056 — genomics — Posted on 2018-08-09

1796 Parkinson’s disease genetics: identifying novel risk loci, providing causal insights and improving estimates of heritable risk

Nalls, M. A.; Blauwendraat, C.; Vallerga, C. L.; Heilbron, K.; Bandres-Ciga, S.; Chang, D.; Tan, M.; Kia, D. A.; Noyce, A. J.; Xue, A.; Bras, J.; Young, E.; von Coelln, R.; Simon-Sanchez, J.; Schulte, C.; Sharma, M.; Krohn, L.; Pihlstrom, L.; Siitonen, A.; Iwaki, H.; Leonard, H.; Faghri, F.; Gibbs, J. R.; Hernandez, D. G.; Scholz, S. W.; Botia, J. A.; Martinez, M.; Corvol, J.-C.; Lesage, S.; Jankovic, J.; Shulman, L. M.; The 23andMe Research Team, ; System Genomics of Parkinson's Disease (SGPD) Consortium, ; Sutherland, M.; Tienari, P.; Majamaa, K.; Toft, M.; Brice, A.; Yang, J.; Gan-Orr, Z

10.1101/388165 — genetics — Posted on 2018-08-09

1797 Positive Selection and Adaptation of Novel Inner Ear Genes in the Mammalian Lineage

Franchini, L. F.; Pisciottano, F.; Cinalli, A. R.; Stopiello, M.; Castagna, V. C.; Gomez-Casati, M. E.; Elgoyhen, B. A.; Rubinstein, M.

10.1101/388496 — evolutionary biology — Posted on 2018-08-09

1798 ChIP-seq meta-analysis yields high quality training sets for enhancer classification

Imrichova, H.; Aerts, S.

10.1101/388934 — bioinformatics — Posted on 2018-08-09

1799 Abnormalities of placental development and function are associated with the different fetal growth patterns of hypoplastic left heart syndrome and transposition of the great arteries.

Troja, W.; Owens, K. J.; Courtney, J.; Hinton, A. C.; Hinton, R. B.; Cnota, J. F.; Jones, H. N.

10.1101/388074 — physiology — Posted on 2018-08-09

1800 UBE2G1 Governs the Destruction of Cereblon Neomorphic Substrates

Lu, G.; Weng, S.; Matyskiela, M.; Zheng, X.; Fang, W.; Wood, S.; Surka, C.; Mizukoshi, R.; Lu, C.-C.; Mendy, D.; Jang, I. S.; Wang, K.; Marella, M.; Couto, S.; Cathers, B.; Carmichael, J.; Chamberlain, P.; Rolfe, M.

10.1101/389098 — molecular biology — Posted on 2018-08-09

1801 deepMc: deep Matrix Completion for imputation of single cell RNA-seq data

Mongia, A.; Sengupta, D.; Majumdar, A.

10.1101/387621 — bioinformatics — Posted on 2018-08-09

1802 A speech envelope landmark for syllable encoding in human superior temporal gyrus

Oganian, Y.; Chang, E. F.

10.1101/388280 — neuroscience — Posted on 2018-08-09

1803 Heterodimerization of UNC-13/RIM regulates synaptic vesicle release probability but not priming

Hu, Z.; Kaplan, J. M.; Liu, H.; Li, L.; Nedelcu, D.; Hall, Q.; Wang, W.; Yu, Y.; Zhou, L.

10.1101/388868 — neuroscience — Posted on 2018-08-09

1804 Linking signal detection theory and encoding models to reveal independent neural representations from neuroimaging data

Soto, F. A.; Vucovich, L. E.; Ashby, F. G.

10.1101/254995 — neuroscience — Posted on 2018-08-09

1805 Dysregulation of EMT Drives the Progression to Clinically Aggressive Sarcomatoid Bladder Cancer

Guo, C. C.; Majewski, T.; Zhang, L.; Yao, H.; Bodaruk, J.; Wang, Y.; Zhang, S.; Wang, Z.; Lee, J. G.; Lee, S.; Cogdell, D.; Zhang, M.; Wei, P.; Grossman, H. B.; Kamat, A.; Duplisea, J. J.; Ferguson, J. E.; Huang, H.; Dadhania, V.; Dinney, C.; Weinstein, J.; Baggerly, K.; McConkey, D. J.; Czerniak, B.

10.1101/388264 — genomics — Posted on 2018-08-09

1806 Interpretable genotype-to-phenotype classifiers with performance guarantees

Drouin, A.; Letarte, G.; Raymond, F.; Marchand, M.; Corbeil, J.; Laviolette, F.

10.1101/388348 — genomics — Posted on 2018-08-09

1807 Whole blood transcriptome analysis reveals footprints of cattle adaptation to sub-arctic conditions

Pokharel, K.; Betsha, M. W.; Popov, R.; Honkatukia, M.; Huuki, H.; Lindeberg, H.; Peippo, J.; Reilas, T.; Zarovnyev, S.; Kantanen, J.

10.1101/379925 — genetics — Posted on 2018-08-09

1808 Genome-wide chromatin accessibility and transcriptome profiling show minimal epigenome changes and coordinated transcriptional dysregulation of hedgehog signaling in Danforth’s short tail mice

Orchard, P.; White, J. S.; Thomas, P. E.; Mychalowych, A.; Kiseleva, A.; Hensley, J.; Allen, B.; Parker, S. C. J.; Keegan, C. E.

10.1101/387977 — genetics — Posted on 2018-08-09

1809 Are these cardiomyocytes? Protocol development reveals impact of sample preparation on the accuracy of identifying cardiomyocytes by flow cytometry

Waas, M.; Weerasekera, R.; Kropp, E. M.; Romero-Tejeda, M.; Poon, E.; Boheler, K. R.; Burridge, P. W.; Gundry, R.

10.1101/388926 — developmental biology — Posted on 2018-08-09

1810 Receptor Mediated Delivery of Cas9-Nanobody Induces Cisplatin Synthetic Dose Sensitivity

Roche, P.; Gytz Olesen, H.; Hussain, F.; Liang, Y.; Stub Laursen, N.; Andersen, K. R.; Nagar, B.; Akavia, U. D.

10.1101/389122 — biochemistry — Posted on 2018-08-09

1811 Two factor authorization: Asf1 mediates crosstalk between H3 K14 and K56 acetylation

Cote, J. M.; Kuo, Y.-M.; Henry, R. A.; Scherman, H.; Andrews, A.

10.1101/389064 — biochemistry — Posted on 2018-08-09

1812 Evolutionarily developed connections compromised in schizophrenia

van den Heuvel, M. P.; Scholtens, L. H.; de Lange, S. C.; Pijnenburg, R.; Cahn, W.; van Haren, N. E. M.; Sommer, I.; Li, L.; Preuss, T.; Rilling, J. K.

10.1101/387506 — neuroscience — Posted on 2018-08-09

1813 Functional In vivo Single-cell Transcriptome (FIST) Analysis Reveals Molecular Properties of Light-Sensitive Neurons in Mouse V1

Liu, J.; Pan, N.; Sun, L.; Wang, M.; Zhang, J.; Zuo, Z.; He, S.; Wu, Q.; Wang, X.

10.1101/382002 — neuroscience — Posted on 2018-08-09

1814 Population dynamics and entrainment of basal ganglia pacemakers are shaped by their dendritic arbors

Tiroshi, L.; Goldberg, J. A.

10.1101/388504 — neuroscience — Posted on 2018-08-09

1815 A Pentatricopeptide Repeat Protein in the Plasmodium apicoplast is essential and shows sequence-specific RNA binding

Hicks, J.; Lassadi, I.; Carpenter, E.; Eno, M.; Vardakis, A.; Waller, R. F.; Howe, C.; Nisbet, R. E. R.

10.1101/388728 — microbiology — Posted on 2018-08-09

1816 Defining the toxicity limits on microbial range in a metal-contaminated aquifer

Carlson, H. K.; Price, M. N.; Callaghan, M.; Aaring, A.; Chakraborty, R.; Liu, H.; Arkin, A. P.; Deutschbauer, A. M.

10.1101/388306 — microbiology — Posted on 2018-08-09

1817 Translating GWAS-identified loci for cardiac rhythm and rate using an in vivo, image-based, large-scale genetic screen in zebrafish

von der Heyde, B.; Emmanouilidou, A.; Klingström, T.; Mazzaferro, E.; Vicenzi, S.; Jumaa, S.; Dethlefsen, O.; Snieder, H.; de Geus, E.; Ingelsson, E.; Allalou, A.; Brooke, H. L.; den Hoed, M.

10.1101/385500 — genomics — Posted on 2018-08-09

1818 Systematic dissection of biases in whole-exome and whole-genome sequencing reveals major determinants of coding sequence coverage

Barbitoff, Y. A.; Polev, D. E.; Glotov, A. S.; Serebryakova, E. A.; Shcherbakova, I. V.; Kiselev, A. M.; Kostareva, A. A.; Glotov, O. S.; Predeus, A. V.

10.1101/387639 — genomics — Posted on 2018-08-09

1819 Imperfect Linkage Disequilibrium Generates Phantom Epistasis (& Perils of Big Data)

de los Campos, G.; Sorensen, D. A.; Toro, M. A.

10.1101/388942 — genetics — Posted on 2018-08-09

1820 Selective pressures on human cancer genes along the evolution of mammals

Vicens, A.; Posada, D.

10.1101/388421 — evolutionary biology — Posted on 2018-08-09

1821 Focal cholesterol depletion during Fcγ receptor-mediated phagocytosis contributes to Lyn kinase regulation

Lu, S. M.; Volchuk, A.; Fairn, G.

10.1101/388637 — cell biology — Posted on 2018-08-09

1822 Single-domain antibodies represent novel alternatives to monoclonal antibodies as targeting agents against the human papillomavirus 16 E6 protein

Togtema, M.; Hussack, G.; Dayer, G.; Teghtmeyer, M.; Raphael, S.; Tanha, J.; Zehbe, I.

10.1101/388884 — cancer biology — Posted on 2018-08-09

1823 Effects of the anesthetic MS-222 on silver pomfret (Pampus argenteus) juveniles under aquaculture treatment stresses

Yu, N.; Cao, X.; Wang, Y.; Kuang, S.; Hu, J.; Yang, Y.; Xu, S.; Zhang, M.; Sun, Y.; Gu, W.; Yan, X.

10.1101/388371 — animal behavior and cognition — Posted on 2018-08-09

1824 Biochemical mechanisms driving rapid fluxes in C4 photosynthesis

Brautigam, A.; Schluter, U.; Lundgren, M. R.; Flachbart, S.; Ebenhoh, O.; Schonknecht, G.; Christin, P.-A.; Bleuler, S.; Droz, J.-M.; Osborne, C.; Weber, A.; Gowik, U.

10.1101/387431 — plant biology — Posted on 2018-08-09

1825 A conserved role of the insulin-like signaling pathway in uric acid pathologies revealed in Drosophila melanogaster

Lang, S.; Bose, N.; Wilson, K.; Brackman, D.; Hilsabeck, T.; Watson, M.; Beck, J.; Sharma, A.; Chen, L.; Killilea, D.; Ho, S.; Kahn, A.; Giacomini, K.; Stoller, M.; Chi, T.; Kapahi, P.

10.1101/387779 — pathology — Posted on 2018-08-09

1826 Atypical functional connectivity in adolescents and adults with persistent and remitted ADHD

Michelini, G.; Jurgiel, J.; Bakolis, I.; Cheung, C. H.; Asherson, P.; Loo, S. K.; Kuntsi, J.; Mohammad-Rezazadeh, I.

10.1101/201772 — neuroscience — Posted on 2018-08-09

1827 Three-dimensional nanostructure of an intact microglia cell

Bolasco, G.; Weinhard, L.; Boissonnet, T.; Neujahr, R.; Gross, C. T.

10.1101/388538 — neuroscience — Posted on 2018-08-09

1828 A transmissible RNA pathway in honey bees

Maori, E.; Garbian, Y.; Kunik, V.; Mozes-Koch, R.; Malka, O.; Kalev, H.; Sabath, N.; Sela, I.; Shafir, S.

10.1101/299800 — molecular biology — Posted on 2018-08-09

1829 Longitudinal Surveys Show that Urethral Catheters Harbor Recurrent Polymicrobial Biofilms with Cooperative and Competitive Behaviors Among Cohabitating Pathogens

Yu, Y.; Singh, H.; Tsitrin, T.; Bekele, S.; Moncera, K. J.; Sikorski, P.; Torralba, M.; Morrow, L.; Wolcott, R. D.; Nelson, K. E.; Pieper, R.

10.1101/388389 — microbiology — Posted on 2018-08-09

1830 Candidate genes under balancing selection in a plant bacterial pathogen

Castillo, J. A.; Agathos, S. N.

10.1101/388207 — microbiology — Posted on 2018-08-09

1831 Adaptor protein Bbc1 regulates localization of Wsp1 and Vrp1 during endocytic actin patch assembly

MacQuarrie, C. D.; Mangione, M.; Carroll, R.; James, M.; Gould, K. L.; Sirotkin, V.

10.1101/389015 — cell biology — Posted on 2018-08-09

1832 Evidence for phospholipid export from the gram-negative inner membrane: time to rethink the Mla pathway?

Hughes, G. W.; Hall, S. C. L.; Laxton, C. S.; Sridhar, P.; Mahadi, A. H.; Hatton, C.; Piggot, T. J.; Jamshad, M.; Spana, V.; Cadby, I. T.; Harding, C.; Isom, G. L.; Bryant, J. A.; Parr, R. J.; Yakub, Y.; Jeeves, M.; Huber, D.; Henderson, I. R.; Clifton, L. A.; Lovering, A. L.; Knowles, T.

10.1101/388546 — biophysics — Posted on 2018-08-09

1833 Intracellular mass density increase is accompanying but not sufficient for stiffening and growth arrest of yeast cells

Abuhattum, S.; Kim, K.; Franzmann, T. M.; Esslinger, A.; Midtvedt, D.; Schluessler, R.; Moellmert, S.; Kuan, H.-S.; Alberti, S.; Zaburdaev, V.; Guck, J.

10.1101/388876 — biophysics — Posted on 2018-08-09

1834 Parallel evolution of frog antimicrobial peptides produces identical conformations but subtly distinct membrane and antibacterial activities

Manzo, G.; Ferguson, P. M.; Hind, C.; Clifford, M.; Gustilo, V. B.; Ali, H.; Bansal, S. S.; Bui, T. T.; Drake, A. F.; Atkinson, R. A.; Sutton, M. J.; Lorenz, C. D.; Phoenix, D. A.; Mason, A. J.

10.1101/388967 — biophysics — Posted on 2018-08-09

1835 Reliable variant calling during runtime of Illumina sequencing

Loka, T. P.; Tausch, S. H.; Renard, B. Y.

10.1101/387662 — bioinformatics — Posted on 2018-08-09

1836 Perceptual decisions result from the continuous accumulation of memory and sensory evidence

Bornstein, A. M.; Aly, M.; Feng, S.; Turk-Browne, N. B.; Norman, K. A.; Cohen, J. D.

10.1101/186817 — neuroscience — Posted on 2018-08-09

1837 A Swiftian Voyage from Brobdingnag to Lilliput: Freshwater Planctomycetes drifting towards the poles of the genome size spectrum

Andrei, A.-S.; Salcher, M. M.; Mehrshad, M.; Rychtecky, P.; Znachor, P.; Ghai, R.

10.1101/388082 — microbiology — Posted on 2018-08-09

1838 Adaptation of proteins to the cold in Antarctic fish: A role for Methionine?

Berthelot, C.; Clarke, J.; Desvignes, T.; Detrich, H. W.; Flicek, P.; Peck, L. S.; Peters, M.; Postlethwait, J. H.; Clark, M. S.

10.1101/388900 — evolutionary biology — Posted on 2018-08-09

1839 MAP7 family proteins are microtubule-tethered allosteric activators of kinesin-1.

Hooikaas, P. J.; Martin, M.; Kuijntjes, G.-J.; Peeters, C. A. E.; Katrukha, E. A.; Ferrari, L.; Stucchi, R.; Verhagen, D. G. F.; van Riel, W. E.; Altelaar, A. F. M.; Hoogenraad, C. C.; Rudiger, S. G. D.; Kapitein, L. C.; Akhmanova, A.

10.1101/388512 — cell biology — Posted on 2018-08-09

1840 bin3C : Exploiting Hi-C sequencing data to accurately resolve metagenome-assembled genomes (MAGs)

DeMaere, M. Z.; Darling, A. E.

10.1101/388355 — bioinformatics — Posted on 2018-08-09

1841 Parallel pattern of differentiation at a genomic island shared between clinal and mosaic hybrid zones in a complex of cryptic seahorse lineages

Riquet, F.; Liautard-Haag, C.; Woodall, L.; Bouza, C.; Louisy, P.; Hamer, B.; Otero-Ferrer, F.; Aublanc, P.; Beduneau, V.; Briard, O.; El Ayari, T.; Hochscheid, S.; Belkhir, K.; Arnaud-Haond, S.; Gagnaire, P.-A.; Bierne, N.

10.1101/161786 — evolutionary biology — Posted on 2018-08-09

1842 Insights into autophagosome biogenesis from structural and biochemical analyses of the ATG2A-WIPI4 complex

Chowdhury, S.; Otomo, C.; Leitner, A.; Ohashi, K.; Aebersold, R.; Lander, G. C.; Otomo, T.

10.1101/180315 — biochemistry — Posted on 2018-08-09

1843 Mode Of Sucrose Delivery Alters Reward-Related Phasic Dopamine Signals In Nucleus Accumbens

McCutcheon, J.; Roitman, M. F.

10.1101/132126 — neuroscience — Posted on 2018-08-09

1844 Epigenetic analyses of planarian stem cells demonstrate conservation of bivalent histone modifications in animal stem cells.

Dattani, A.; Kao, D.; Mihaylova, Y.; Abnave, P.; Hughes, S.; Lai, A.; Sahu, S.; Aboobaker, A.

10.1101/122135 — developmental biology — Posted on 2018-08-09

1845 Glucocorticoids and cortical decoding in the phobic brain

Schwab, S.; Federspiel, A.; Morishima, Y.; Nakataki, M.; Strik, W.; Wiest, R.; Heinrichs, M.; de Quervain, D.; Soravia, L. M.

10.1101/099697 — neuroscience — Posted on 2018-08-09

1846 Coalescence and linkage disequilibrium in facultatively sexual diploids

Hartfield, M.; Wright, S.; Agrawal, A.

10.1101/232405 — evolutionary biology — Posted on 2018-08-09

1847 Measurements of the self-assembly kinetics of individual viral capsids around their RNA genome

Garmann, R. F.; Goldfain, A. M.; Manoharan, V. N.

10.1101/265330 — biophysics — Posted on 2018-08-09

1848 GLUE: A flexible software system for virus sequence data

Singer, J. B.; Thomson, E. C.; McLauchlan, J.; Hughes, J.; Gifford, R. J.

10.1101/269274 — bioinformatics — Posted on 2018-08-09

1849 Minor sequence modifications in temporin B cause drastic changes in antibacterial potency and selectivity by fundamentally altering membrane activity

Manzo, G.; Ferguson, P. M.; Gustilo, V. B.; Bui, T. T.; Drake, A. F.; Atkinson, R. A.; Batoni, G.; Lorenz, C. D.; Phoenix, D. A.; Mason, A. J.

10.1101/312215 — biophysics — Posted on 2018-08-09

1850 Modelling structural determinants of ventilation heterogeneity: a perturbative approach.

Whitfield, C. A.; Horsley, A.; Jensen, O. E.

10.1101/329961 — biophysics — Posted on 2018-08-09

1851 TreeSwift: a massively scalable Python tree package

Moshiri, N.

10.1101/325522 — bioinformatics — Posted on 2018-08-09

1852 Variation in expression of the HECT E3 ligase UPL3modulates LEC2 levels, gene expression, seed sizeand crop yields in Brassica napus.

Miller, C.; Wells, R.; McKenzie, N.; Trick, M.; Ball, J.; Fatihi, A.; Debreuq, B.; Chardot, T.; Lepiniec, L.; Bevan, M. W.

10.1101/334581 — plant biology — Posted on 2018-08-09

1853 Thalamus, subiculum and retrosplenial cortex encode 3D head direction information in volumetric space

Kim, M.; Maguire, E. A.

10.1101/335976 — neuroscience — Posted on 2018-08-09

1854 High Precision Detection of Rare Splice Isoforms Using Multiplexed Primer Extension Sequencing

Xu, H.; Fair, B. J.; Dwyer, Z.; Gildea, M.; Pleiss, J. A.

10.1101/331629 — molecular biology — Posted on 2018-08-09

1855 Delayed start of first-time breeding and non-breeders surplus in the Western Siberian population of the European Pied Flycatcher

Grinkov, V. G.; Sternberg, H.

10.1101/387829 — zoology — Posted on 2018-08-09

1856 Forecasting bacterial survival-success and adaptive evolution through multi-omics stress response-mapping, network analyses and machine learning

Zhu, Z.; Surujon, D.; Pavao, A.; Bento, J.; van Opijnen, T.

10.1101/387910 — microbiology — Posted on 2018-08-09

1857 Excitable dynamics of Ras triggers self-organized PIP3 signaling for spontaneous cell migration

Fukushima, S.; Matsuoka, S.; Ueda, M.

10.1101/356105 — cell biology — Posted on 2018-08-09

1858 Homing and egg discrimination in the Western Slimy Salamander, Plethodon albagula (Caudata: Plethodontidae)

Jordan, R.; Milanovich, J. R.; McCallum, M.; Trauth, S. E.

10.1101/388249 — animal behavior and cognition — Posted on 2018-08-09

1859 Evaluation of a Dual Isolation Width Acquisition (DIWA) method for isobaric labelling ratio decompression

Roumeliotis, T. I.; Weisser, H.; Choudhary, J. S.

10.1101/387878 — systems biology — Posted on 2018-08-09

1860 Parallel Evolution and the Emergence of Highly Pathogenic Avian Influenza A Viruses

Escalera-Zamudio, M.; Gutierrez, B.; Theze, J.; Russell Keown, J.; Carrique, L.; Bowden, T. A.; Pybus, O. G.

10.1101/370015 — evolutionary biology — Posted on 2018-08-09

1861 A Critical Role of YB-1 In The Genesis And Progression Of KRAS Mutated Human Breast Cancer

Lefort, S.; El-Naggar, A.; Tan, S.; Colborne, S.; Negri, G. L.; Pellacani, D.; Hirst, M.; Gusterson, B.; Morin, G. B.; Sorensen, P. H.; Eaves, C. J.

10.1101/372524 — cancer biology — Posted on 2018-08-09

1862 The architecture of the human RNA-binding protein regulatory network

Quattrone, A.; Dassi, E.

10.1101/041426 — systems biology — Posted on 2018-08-09

1863 Measuring Illumina Size Bias Using REcount: A Novel Method for Highly Accurate Quantification of Engineered Genetic Constructs

Gohl, D. M.; Becker, A.; Johnson, D.; Anderson, S.; Billstein, B.; McDevitt, S. L.; Beckman, K. B.

10.1101/388108 — genomics — Posted on 2018-08-09

1864 Curcumin inhibits cystogenesis in autosomal dominant polycystic kidney disease cells via altering JAK2/STAT3 activity

Patera, F.; Cudzuch-Mardy, A.; Huang, Z.; Fragiadaki, M.

10.1101/378919 — cell biology — Posted on 2018-08-09

1865 A computational model of loss of dopaminergic cells in Parkinson’s disease due to glutamate-induced excitotoxicity

Muddapu, V. R.; Mandali, A.; Chakravarthy, S. V.; Ramaswamy, S.

10.1101/385138 — neuroscience — Posted on 2018-08-09

1866 A nanotube-mediated path to protocell formation

Koksal, E. S.; Liese, S.; Kantarci, I.; Olsson, R.; Carlson, A.; Gozen, I.

10.1101/388405 — biophysics — Posted on 2018-08-09

1867 Loss of Frrs1l disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities

Stewart, M.; Lau, P. Y.; Banks, G.; Bains, R. S.; Castroflorio, E.; Oliver, P. L.; Dixon, C. L.; Kruer, M. C.; Kullman, D. M.; Acevedo-Arozena, A.; Wells, S. E.; Corrochano, S.; Nolan, P.

10.1101/388561 — neuroscience — Posted on 2018-08-09

1868 SP1 and STAT3 functionally synergize to induce the RhoU small GTPase and a subclass of non-canonical WNT responsive genes correlating with poor prognosis in breast cancer.

Monteleone, E.; Orecchia, V.; Corrieri, P.; Schiavone, D.; Avalle, L.; Moiso, E.; Savino, A.; Molineris, I.; Provero, P.; Poli, V.

10.1101/387951 — cancer biology — Posted on 2018-08-09

1869 Flexibly-oriented double Cdc45-MCM-GINS intermediates during eukaryotic replicative helicase maturation

Liu, L.; Zhang, Y.; Zhang, J.; Wang, J.-H.; Cao, Q.; Li, Z.; Campbell, J. L.; Dong, M.; Lou, H.

10.1101/388470 — molecular biology — Posted on 2018-08-09

1870 tudor-domain containing protein 5-prime promotes male sexual identity in the Drosophila germline and is repressed in females by Sex lethal

Primus, S.; Pozmanter, C.; Baxter, K.; Van Doren, M.

10.1101/388850 — developmental biology — Posted on 2018-08-09

1871 Transposable Element Expression In Tumors Is Associated With Immune Infiltration And Increased Antigenicity

Kong, Y.; Rose, C.; Cass, A. A.; Darwish, M.; Lianoglou, S.; Haverty, P. M.; Tong, A.-J.; Blanchette, C.; Mellman, I.; Bourgon, R.; John, G.; Jhunjhunwala, S.; Albert, M. L.; Chen-Harris, H.

10.1101/388215 — cancer biology — Posted on 2018-08-09

1872 Health-seeking behavior and associated factors among community in Southern Ethiopia: Community based cross-sectional study guided by Health belief model.

Asfaw, L. S.; Ayanto, S. Y.; Aweke, Y. H.

10.1101/388769 — scientific communication and education — Posted on 2018-08-09

1873 Modern botanical analogue of endangered Yak (Bos mutus) dung from India: Plausible linkage with living and extinct megaherbivores

Basumatary, S.; Singh, H.; McDonald, H. G.; Tripathi, S.; Pokharia, A. K.

10.1101/388819 — paleontology — Posted on 2018-08-09

1874 Individual-based network model for Rift Valley Fever in Kabale District, Uganda, to guide mitigation measures: A One Health Model

Sekamatte, M.; Riad, M. H.; Tekleghiorghis, T.; Linthicum, K. J.; Britch, S. C.; Richt, J. A.; Gonzalez, J. P.; Scoglio, C. M.

10.1101/388785 — epidemiology — Posted on 2018-08-09

1875 Very high-density platelets determine reactivity and activity of circulating platelets

Jaremo, P.

10.1101/388744 — cell biology — Posted on 2018-08-09

1876 Somatic mutations in early metazoan genes disrupt regulatory links between unicellular and multicellular genes in cancer

Trigos, A. S.; Pearson, R. B.; Papenfuss, A. T.; Goode, D. L.

10.1101/388363 — cancer biology — Posted on 2018-08-09

1877 High-throughput characterisation of bull semen motility using differential dynamic microscopy

Martinez, V. A.; Jepson, A.; Arlt, J.; Statham, J.; Spilman, M.; Burton, K.; Wood, T.; Poon, W. C. K.

10.1101/388777 — biophysics — Posted on 2018-08-09

1878 Monocyte depletion attenuates the development of posttraumatic hydrocephalus and preserves white matter integrity after traumatic brain injury

Makinde, H. M.; Just, T. B.; Cuda, C. M.; Bertolino, N.; Procissi, D.; Schwulst, S. J.

10.1101/388793 — neuroscience — Posted on 2018-08-09

1879 Microorganism adhesion experimental study using silicon dioxide

Lozins, R.; Ozolins, D.

10.1101/388694 — microbiology — Posted on 2018-08-09

1880 Artificial Selection on Storage Protein 1 Contributes to Increase of Hatchability during Silkworm Domestication

Zhu, Y. n.; Wang, L. Z.; Li, C. C.; Cui, Y.; Wang, M.; Lin, Y. J.; Zhao, R. P.; Wang, W.; Xiang, H.

10.1101/388843 — evolutionary biology — Posted on 2018-08-09

1881 Understanding narwhal diving behaviour using Hidden Markov Models with dependent state distributions and long range dependence

Ngo, M. C.; Heide-Jorgensen, M. P.; Ditlevsen, S.

10.1101/388835 — ecology — Posted on 2018-08-09

1882 The single mitochondrion of the kinetoplastid parasite Crithidia fasciculata is a dynamic network

DiMaio, J.; Ruthel, G.; Cannon, J.; Malfara, M.; Povelones, M. L.

10.1101/388660 — cell biology — Posted on 2018-08-09

1883 Variations in neonatal age segments mortality in Kenyas malaria epidemiological zones by community uptake of iron-supplements and anti-malaria drugs during pregnancy: Analysis based on 2014 Kenya demographic and health survey

K'Oyugi, B. O.

10.1101/388652 — epidemiology — Posted on 2018-08-09

1884 Landscape structure influences avian species diversity in tropical urban mosaics

Muderere, T.; Murwira, A.; Tagwireyi, P.; Chiweshe, N.

10.1101/388702 — ecology — Posted on 2018-08-09

1885 Identification of dysregulation of atrial proteins in rats with chronic obstructive apnea using two-dimensional polyacrylamide gel electrophoresis and mass spectrometry

Lux, J. C.; Channaveerappa, D.; Aslebagh, R. C.; Heintz, T. A.; McLerie, M.; Panama, B. K.; Darie, C.

10.1101/388751 — biochemistry — Posted on 2018-08-09

1886 DAIRYdb: A manually curated gold standard reference database for improved taxonomy annotation of 16S rRNA gene sequences from dairy products

Meola, M.; Rifa, E.; Shani, N.; Delbes, C.; Berthoud, H.; Chassard, C.

10.1101/386151 — genomics — Posted on 2018-08-09

1887 Superior dispersal ability leads to persistent ecological dominance by Candida pseudoglaebosa in the Sarracenia purpurea fungal metacommunity

Boynton, P. J.; Peterson, C. N.; Pringle, A.

10.1101/387753 — ecology — Posted on 2018-08-09

1888 Real time monitoring of transtibial elevated vacuum prostheses: a case series on socket air pressure

Schoepp, K. R.; Schofield, J. S.; Home, D.; Dawson, M. R.; Lou, E.; Keri, M.; Marasco, P. D.; Hebert, J. S.

10.1101/388736 — bioengineering — Posted on 2018-08-09

1889 Measuring researcher independence using bibliometric data: A proposal for a new performance indicator

Van den Besselaar, P.; Sandström, U.

10.1101/388678 — scientific communication and education — Posted on 2018-08-09

1890 Contrast sensitivity reveals an oculomotor strategy for temporally encoding space

Casile, A.; Victor, J.; Rucci, M.

10.1101/388132 — neuroscience — Posted on 2018-08-09

1891 Atypical flexibility in dynamic functional connectivity quantifies the severity in autism spectrum disorder

Harlalka, V.; Raju, B. S.; Krishnanunni, V. P.; Roy, D.

10.1101/387886 — neuroscience — Posted on 2018-08-09

1892 Voxelwise encoding models with non-spherical multivariate normal priors

Nunez-Elizalde, A. O.; Huth, A. G.; Gallant, J. L.

10.1101/386318 — neuroscience — Posted on 2018-08-09

1893 Proton Conductivity of Glycosaminoglycans

Rolandi, M.; Selberg, J.; Jia, M.

10.1101/388686 — bioengineering — Posted on 2018-08-09

1894 Molecular bases for the constitutive photomorphogenic phenotypes in Arabidopsis

Huq, E.; Pham, V.; Xu, X.

10.1101/388157 — plant biology — Posted on 2018-08-09

1895 The genetics and genome-wide screening of perennialism loci in Zea diploperennis

Ma, A.; Qiu, Y.; Raihan, T.; Dahal, S.; Zhuang, Y.; Galla, A.; Auger, D. L.; Yen, Y.

10.1101/388256 — plant biology — Posted on 2018-08-09

1896 Motor cortical beta transients delay movement initiation and track errors

Little, S.; Bonaiuto, J.; Barnes, G.; Bestmann, S.

10.1101/384370 — neuroscience — Posted on 2018-08-09

1897 SyngenicDNA: stealth-based evasion of restriction-modification barriers during bacterial genetic engineering

Johnston, C. D.; Cotton, S. L.; Rittling, S. R.; Starr, J. R.; Borisy, G.; Dewhirst, F.; Lemon, K. P.

10.1101/387985 — microbiology — Posted on 2018-08-09

1898 Virus-inclusive single cell RNA sequencing reveals molecular signature predictive of progression to severe dengue infection

Zanini, F.; Robinson, M.; Croote, D.; Sahoo, M. K.; Sanz, A. M.; Ortiz-Lasso, E.; Albornoz, L. L.; Suarez, F. R.; Montoya, J. G.; Pinsky, B. A.; Quake, S.; Einav, S.

10.1101/388181 — immunology — Posted on 2018-08-09

1899 Measuring Illumina Size Bias Using REcount: A Novel Method for Highly Accurate Quantification of Engineered Genetic Constructs

Gohl, D. M.; Becker, A.; Johnson, D.; Anderson, S.; Billstein, B.; McDevitt, S. L.; Beckman, K. B.

10.1101/388108 — genomics — Posted on 2018-08-09

1900 Predicting the future direction of cell movement with convolutional neural networks

Nishimoto, S.; Tokuoka, Y.; Yamada, T. G.; Hiroi, N.; Funahashi, A.

10.1101/388033 — systems biology — Posted on 2018-08-09

1901 Transcriptome analysis of mycorrhizal and non-mycorrhizal soybean plantlets upon infection with Fusarium virguliforme, one causal agent of sudden death syndrome

Marquez, N.; Giachero, M. L.; Gallou, A.; Debat, H.; Declerck, S.; Ducasse, D. A.

10.1101/388025 — plant biology — Posted on 2018-08-09

1902 Human frontoparietal cortex represents behaviorally-relevant target status during invariant object recognition

Henderson, M. M.; Serences, J.

10.1101/387498 — neuroscience — Posted on 2018-08-09

1903 Rapid Diagnosis of Lower Respiratory Infection using Nanopore-based Clinical Metagenomics

Charalampous, T.; Richardson, H.; Kay, G. L.; Baldan, R.; Jeanes, C.; Rae, D.; Grundy, S.; Turner, D. J.; Wain, J.; Leggett, R. M.; Livermore, D. M.; O'Grady, J.

10.1101/387548 — microbiology — Posted on 2018-08-09

1904 Systems biology reveals NR2F6 and TGFB1 as key regulators of feed efficiency in beef cattle

Alexandre, P. A.; Naval-Sanchez, M.; Porto-Neto, L. R.; Ferraz, J. B. S.; Reverter, A.; Fukumasu, H.

10.1101/360396 — systems biology — Posted on 2018-08-09

1905 Mutant p63 affects epidermal cell identity through rewiring the enhancer landscape

Qu, J.; Tanis, S.; Smits, J. P.; Kouwenhoven, E. N.; Oti, M.; van den Bogaard, E. H.; Logie, C.; Stunnenberg, H.; van Bokhoven, H.; Mulder, K. W.; Zhou, H.

10.1101/387902 — molecular biology — Posted on 2018-08-09

1906 Sensitivity of heat detection attentions and their relation with the moment of LH surge in dairy cows

Adriaens, I.; Saeys, W.; Lamberigts, C.; Berth, M.; Geerinckx, K.; Leroy, J.; De Ketelaere, B.; Aernouts, B.

10.1101/249169 — bioengineering — Posted on 2018-08-09

1907 Hampered motility promotes the evolution of wrinkly phenotype in Bacillus subtilis

Richter, A.; Holscher, T.; Pausch, P.; Sehrt, T.; Brockhaus, F.; Bange, G.; Kovacs, A. T.

10.1101/288951 — microbiology — Posted on 2018-08-09

1908 HSP-4/BiP expression in secretory cells is regulated by a lineage-dependent differentiation program and not by the unfolded protein response

Zha, J.; Alexander-Floyd, J.; Gidalevitz, T.

10.1101/388272 — cell biology — Posted on 2018-08-09

1909 Perceptual and memory neural processes underlie short and long-term non-reinforced behavioral change

Botvinik-Nezer, R.; Salomon, T.; Schonberg, T.

10.1101/363044 — neuroscience — Posted on 2018-08-08

1910 Cholinergic Midbrain Afferents Modulate Striatal Circuits and Shape Encoding of Action Control

Dautan, D.; Huerta-Ocampo, I.; Valencia, M.; Kondabolu, K.; Gerdjikov, T. V.; Mena-Segovia, J.

10.1101/388223 — neuroscience — Posted on 2018-08-08

1911 Identification of Functional Targets Reveals that the Suppression of Pumilio mediated mRNA Decay Increases Cell Resistance to DNA Damage in Human Cells

Yamada, T.; Imamachi, N.; Imamura, K.; Kawamura, T.; Nagahama, M.; akimitsu, n.

10.1101/387381 — molecular biology — Posted on 2018-08-08

1912 Magnaporthe oryzae SMO1 encodes a Ras GTPase-activating protein required for spore morphology, appressorium function and rice blast disease

Kershaw, M. J.; Basiewicz, M.; Soanes, D.; Yan, X.; Ryder, L. S.; Csukai, M.; Valent, B.; Nicholas, T.

10.1101/388298 — microbiology — Posted on 2018-08-08

1913 Deterministic Nature of Cellular Position Noise During C. elegans Embryogenesis

Li, X.; Zhao, Z.; Xu, W.; Fan, R.; Xiao, L.; Ma, X.; Du, Z.

10.1101/385609 — developmental biology — Posted on 2018-08-08

1914 Efficiency and precision of miRNA biogenesis modes in plants

Moro, B.; Chorostecki, U. P.; Arikit, S.; Suarez, I. P.; Hobartner, C.; Rasia, R.; Meyers, B.; Palatnik, J.

10.1101/388330 — molecular biology — Posted on 2018-08-08

1915 Early and Late Effects of Maternal Experience on Hippocampal Neurogenesis, Microglia, and the Circulating Cytokine Milieu

Mahmoud, R.; Chaiton, J. A.; Lieblich, S. E.; Bodnar, T. S.; Weinberg, J.; Galea, L.

10.1101/388009 — neuroscience — Posted on 2018-08-08

1916 Morphology of Mitochondria in Spatially Restricted Axons Revealed by Cryo-Electron Tomography

Fischer, T. D.; Dash, P. K.; Liu, J.; Waxham, M. N.

10.1101/273052 — neuroscience — Posted on 2018-08-08

1917 Pericarp Pigmentation Correlates with Hormones and Intensifies with Continuation of Bud Sport Generations from ‘Red Delicious’

Li, W.-F.; Mao, J.; Yang, S.-J.; Guo, Z.-G.; Ma, Z.-H.; Dawuda, M. M.; Zuo, C.-W.; Chu, M.-Y.; Chen, B.-H.

10.1101/336263 — bioinformatics — Posted on 2018-08-08

1918 3D Shape Modeling for Cell Nuclear Morphological Analysis and Classification

Kalinin, A. A.; Allyn-Feuer, A.; Ade, A.; Fon, G.-V.; Meixner, W.; Dilworth, D.; Husain, S. S.; de Wet, J. R.; Higgins, G. A.; Zheng, G.; Creekmore, A.; Wiley, J. W.; Verdone, J. E.; Veltri, R. W.; Pienta, K. J.; Coffey, D. S.; Athey, B. D.; Dinov, I. D.

10.1101/313411 — bioinformatics — Posted on 2018-08-08

1919 Resource diversity structures aquatic bacterial communities

Muscarella, M. E.; Boot, C. M.; Broeckling, C. D.; Lennon, J. T.

10.1101/387803 — microbiology — Posted on 2018-08-08

1920 A pivotal role of serine 225 phosphorylation in the function of hepatitis C virus NS5A revealed with the application of a phosphopeptide antiserum and super-resolution microscopy

Goonawardane, N.; Yin, C.; Harris, M.

10.1101/387407 — microbiology — Posted on 2018-08-08

1921 Normalization of generalized transcript degradation improves accuracy in RNA-seq analysis

Xiong, B.; Yang, Y.; Fineis, F.; Wang, J.-P.

10.1101/386938 — bioinformatics — Posted on 2018-08-08

1922 Bayesian weighing of electron cryo-microscopy data for integrative structural modeling

Bonomi, M.; Hanot, S.; Greenberg, C. H.; Sali, A.; Nilges, M.; Vendruscolo, M.; Pellarin, R.

10.1101/113951 — bioinformatics — Posted on 2018-08-08

1923 Risk factors contributing to Bacteraemia at a Tertiary Cancer Center in South Asia

Lenaduwe, S. L. A.; Sandunika, A.; Widanagamage, R.; Dias, P.; Gunesekera, S.

10.1101/386193 — cancer biology — Posted on 2018-08-08

1924 Data-adaptive pipeline for filtering and normalizing metabolomics data.

Schiffman, C.; Petrick, L.; Perttula, K.; Yano, Y.; Carlsson, H.; Whitehead, T.; Metayer, C.; Hayes, J.; Edmands, W. M. B.; Rappaport, S.; Dudoit, S.

10.1101/387365 — bioinformatics — Posted on 2018-08-08

1925 Exploring the effect of microdosing psychedelics on creativity in an open-label natural setting

Prochazkova, L.; Lippelt, D. P.; Calzato, L. S.; Kuchar, M.; Sjoerds, Z.; Hommel, B.

10.1101/384412 — neuroscience — Posted on 2018-08-08

1926 ULK-mediated phosphorylation of ATG16L1 promotes xenophagy, but destabilizes the ATG16L1 Crohn’s mutant

Alsaadi, R. M.; Losier, T. T.; Tian, W.; Guo, Z.; Russell, R. C.

10.1101/387563 — molecular biology — Posted on 2018-08-08

1927 The Tritryps comparative repeatome: insights on repetitive element evolution in Trypanosomatid pathogens

Pita, S.; Diaz-Viraque, F.; Iraola, G.; Robello, C.

10.1101/387217 — genomics — Posted on 2018-08-08

1928 Genome-wide association study, replication, and mega-analysis using a dense marker panel in a multi-generational mouse advanced intercross line

Zhou, X.; St. Pierre, C. L.; Gonzales, N. M.; Cheng, R.; Chitre, A. S.; Sokoloff, G.; Palmer, A. A.

10.1101/387613 — genetics — Posted on 2018-08-08

1929 Mutations in ELAC2 associated with hypertrophic cardiomyopathy impair mitochondrial tRNA 3’-end processing

Saoura, M.; Powell, C. A.; Kopajtich, R.; Alahmad, A.; AL-Balool, H. H.; Albash, B.; Alfadhel, M.; Alston, C. L.; Bertini, E.; Bonnen, P.; Bratkovic, D.; Carrozzo, R.; Donati, M. A.; Di Nottia, M.; Ghezzi, D.; Goldstein, A.; Haan, E.; Horvath, R.; Hughes, J.; Invernizzi, F.; Lamantea, E.; Lucas, B.; Pinnock, K.-G.; Pujantell, M.; Rahman, S.; Rebelo-Guiomar, P.; Santra, S.; Verrigni, D.; McFarland, R.; Prokisch, H.; Taylor, R. W.; Levinger, L.; Minczuk, M.

10.1101/378448 — genetics — Posted on 2018-08-08

1930 Inferring macro-ecological patterns from local species’ occurrences

Tovo, A.; Formentin, M.; Suweis, S.; Stivanello, S.; Azaele, S.; Maritan, A.

10.1101/387456 — ecology — Posted on 2018-08-08

1931 Neuronal population mechanisms of lightness perception

Ruff, D. A.; Brainard, D. H.; Cohen, M. R.

10.1101/294280 — neuroscience — Posted on 2018-08-08

1932 Identification of evolutionarily conserved virulence factor by selective pressure analysis of Streptococcus pneumoniae

Yamaguchi, M.; Goto, K.; Hirose, Y.; Yamaguchi, Y.; Sumitomo, T.; Nakata, M.; Nakano, K.; Kawabata, S.

10.1101/356212 — microbiology — Posted on 2018-08-08

1933 Proliferation of Superficial Neuromasts During Lateral Line Development in the Round Goby, Neogobius melanostomus

Dickson, J.; Janssen, J. A.

10.1101/386169 — evolutionary biology — Posted on 2018-08-08

1934 Mechanical heterogeneity and roles of parallel microtubule arrays in governing meiotic spindle length

Takagi, J.; Shimamoto, Y.

10.1101/385633 — cell biology — Posted on 2018-08-08

1935 Quality circles for quality improvement in primary health care: their effectiveness, gaps of knowledge, origins and significance - a scoping review

Rohrbasser, A.; Harris, J.; Mickan, S.; Wong, G.

10.1101/387605 — scientific communication and education — Posted on 2018-08-08

1936 Geographically Opposing Responses of Sea Urchin Recruitment to Changes in Ocean Climate

Okamoto, D. K.; Reed, D. C.; Schroeter, S. C.

10.1101/387282 — ecology — Posted on 2018-08-08

1937 Motor Cortex Excitability Reflects the Subjective Value of Reward and Mediates its Effects on Incentive Motivated Performance

Galaro, J. K.; Celnik, P. A.; Chib, V. S.

10.1101/387332 — neuroscience — Posted on 2018-08-08

1938 Simplified neural encoding of social communication reflects lifestyle

Allen, K. M.; Marsat, G.

10.1101/387324 — neuroscience — Posted on 2018-08-08

1939 Serial dependence transfers between perceptual objects

Huffman, G.; Pratt, J.; Honey, C. J.

10.1101/165399 — neuroscience — Posted on 2018-08-08

1940 Bacterial and fungal contributions to delignification and lignocellulose degradation in forest soils with metagenomic and quantitative stable isotope probing

Wilhelm, R. C.; Singh, R.; Eltis, L. D.; Mohn, W. W.

10.1101/387308 — molecular biology — Posted on 2018-08-08

1941 Dub-seq: dual-barcoded shotgun expression library sequencing for high-throughput characterization of functional traits

Mutalik, V. K.; Novichkov, P. S.; Price, M. N.; Owens, T. K.; Callaghan, M.; Carim, S.; Deutschbauer, A. M.; Arkin, A. P.

10.1101/387399 — microbiology — Posted on 2018-08-08

1942 Broad spectrum capture of clinical pathogens using engineered Fc-Mannose-Binding Lectin (FcMBL) enhanced by antibiotic treatment

Seiler, B. T.; Cartwright, M.; Dinis, A. L. M.; Duffy, S.; Lombardo, P.; Cartwright, D.; Super, E. H.; Lanzaro, J.; Dugas, K.; Super, M.; Ingber, D. E.

10.1101/387589 — immunology — Posted on 2018-08-08

1943 Exclusive dependence of IL-10Rα signalling on intestinal microbiota homeostasis and control of whipworm infection

Duque-Correa, M. A.; Karp, N. A.; McCarthy, C.; Forman, S.; Goulding, D.; Sankaranarayanan, G.; Jenkins, T. P.; Reid, A. J.; Browne, H. P.; Cambridge, E. L.; Ballesteros Reviriego, C.; Müller, W.; Cantacessi, C.; Dougan, G.; Grencis, R. K.; Berriman, M.; The 3i consortium,

10.1101/388173 — immunology — Posted on 2018-08-08

1944 MULTI-seq: Scalable sample multiplexing for single-cell RNA sequencing using lipid-tagged indices

McGinnis, C. S.; Patterson, D. M.; Winkler, J.; Hein, M. Y.; Srivastava, V.; Conrad, D. N.; Murrow, L. M.; Weissman, J. S.; Werb, Z.; Chow, E. D.; Gartner, Z. J.

10.1101/387241 — genomics — Posted on 2018-08-08

1945 Myc is dispensable for cardiac development in the mouse but rescues Mycn-deficient hearts through functional replacement and cell competition

Munoz-Martin, N.; Sierra, R.; Schimmang, T.; Villa del Campo, C.; Torres, M.

10.1101/357335 — developmental biology — Posted on 2018-08-08

1946 Molecular Heterogeneity and Early Metastatic Clone Selection in Testicular Germ Cell Cancer Development

Dorssers, L. C.; Gillis, A. J.; Stoop, H.; van Marion, R.; Nieboer, M. M.; van Riet, J.; van de Werken, H. J.; Oosterhuis, J. W.; de Ridder, J.; Looijenga, L. H.

10.1101/385807 — cancer biology — Posted on 2018-08-08

1947 Modulation of Human Hsp90α Conformational Dynamics by Allosteric Ligand Interaction at the C-Terminal Domain

Penkler, D. L.; Tastan Bishop, O.

10.1101/386755 — bioinformatics — Posted on 2018-08-08

1948 An algorithm-centric Monte Carlo method to empiricallyquantify motion type estimation uncertainty in single-particle tracking

Rigano, A.; Galli, V.; Gonciarz, K.; Sbalzarini, I. F.; Strambio-De-Castillia, C.

10.1101/379255 — bioinformatics — Posted on 2018-08-08

1949 A chemical biology view of bioactive small molecules and a binder-based approach to connect biology to precision medicines

Schreiber, S.

10.1101/386904 — biochemistry — Posted on 2018-08-08

1950 NKB Signaling in the Medial Amygdala Stimulates Gonadotropin Release in a Kisspeptin-Independent Manner in Female Mice

Fergani, C.; Leon, S.; Padilla, S. L.; Verstegen, A. M.; Palmiter, R. D.; Navarro, V. M.

10.1101/387555 — neuroscience — Posted on 2018-08-08

1951 Tracking a Serial Killer: Integrating Phylogenetic Relationships, Epidemiology, and Geography for Two Invasive Meningococcal Disease Outbreaks

Ezeoke, I.; Galac, M.; Lin, Y.; Liem, A. T.; Roth, P. A.; Kilianski, A.; Gibbons, H. S.; Bloch, D.; Kornblum, J.; Del Rosso, P.; Janies, D. A.; Weiss, D.

10.1101/387597 — genomics — Posted on 2018-08-08

1952 Prevalence of Depression among Epileptic Patients and its Association with Drug Therapy: A Systematic Review and Meta-Analysis.

Dessie, G.; Mulugeta, H.; Tessema, C. L.; Wagnew, F.; Burrowes, S.; Getenet Dessie1*, Henok Mulugeta1, Cheru Tesema Leshargie2, Fasil Wagnew1, Sahai Burrowes1,

10.1101/387571 — neuroscience — Posted on 2018-08-08

1953 Modular assembly of polysaccharide-degrading microbial communities in the ocean

Enke, T. N.; Datta, M. S.; Schwartzman, J.; Cermak, N.; Schmitz, D.; Barrere, J.; Cordero, O. X.

10.1101/387191 — microbiology — Posted on 2018-08-08

1954 Pathway and network analysis of more than 2,500 whole cancer genomes

Reyna, M. A.; Haan, D.; Paczkowska, M.; Verbeke, L. P. C.; Vazquez, M.; Kahraman, A.; Pulido Tamayo, S.; Barenboim, J.; Wadi, L.; Dhingra, P.; Shrestha, R.; Getz, G.; Lawrence, M. S.; Pedersen, J. S. S.; Rubin, M. A.; Wheeler, D. A.; Brunak, S.; Izarzugaza, J. M.; Khurana, E.; Marchal, K.; von Mering, C.; Sahinalp, S. C.; Valencia, A.; Reimand, J.; Stuart, J. M.; Raphael, B. J.; PCAWG Drivers and Functional Annotation Group, ; ICGC/TCGA Pan-Cancer Analysis of Whole Genomes,

10.1101/385294 — cancer biology — Posted on 2018-08-07

1955 In Vitro Expansion of Keratinocytes on Human Dermal Fibroblast-Derived Matrix Retains Their Stem-Like Characteristics

Wong, C. W.; Kinnear, B. F.; Sobota, R. M.; Ramalingam, R.; Legrand, C. F.; Dye, D. E.; Raghunath, M.; Lane, B.; Coombe, D. R.

10.1101/381178 — cell biology — Posted on 2018-08-07

1956 Tandem repeats contribute to coding sequence variation in bumblebees (Hymenoptera: Apidae)

Zhao, X.; Su, L.; Schaack, S.; Sadd, B. M.; Sun, C.

10.1101/201459 — genomics — Posted on 2018-08-07

1957 Nearly Neutral Evolution Across the Drosophila melanogaster Genome

Castellano, D.; James, J.; Eyre-Walker, A.

10.1101/212779 — evolutionary biology — Posted on 2018-08-07

1958 Conbase: a software for unsupervised discovery of clonal somatic mutations in single cells through read phasing

Hard, J.; Al Hakim, E.; Kindblom, M.; Bjorklund, A.; Demirci, I.; Paterlini, M.; Reu, P.; Sennblad, B.; Borgstrom, E.; Stahl, P. L.; Michaelsson, J.; Mold, J. E.; Frisen, J.

10.1101/259994 — bioinformatics — Posted on 2018-08-07

1959 Temporal metacognition as the decoding of self-generated brain dynamics

Kononowicz, T. W.; Roger, C.; van Wassenhove, V.

10.1101/206086 — neuroscience — Posted on 2018-08-07

1960 Information-rich localization microscopy through machine learning

Kim, T.; Moon, S.; Xu, K.

10.1101/373878 — biophysics — Posted on 2018-08-07

1961 Neurobehavioural Correlates of Obesity are Largely Heritable

Vainik, U.; Baker, T. B.; Dadar, M.; Zeighami, Y.; Michaud, A.; Zhang, Y.; Alanis, J. C. G.; Misic, B.; Collins, D. L.; Dagher, A.

10.1101/204917 — neuroscience — Posted on 2018-08-07

1962 Transgenerational sterility of Piwi pathway mutants in response to germ granule dysfunction

Kretovich Billmyre, K.; Heestand, B.; Spichal, M.; Frenk, S.; Ahmed, S.

10.1101/276782 — developmental biology — Posted on 2018-08-07

1963 miR-132 controls mouse pancreatic beta cell proliferation and survival through the Pten/Akt/Foxo3 signaling

MZIAUT, H.; Henniger, G.; Ganss, K.; Hempel, S.; Wolk, S.; McChord, J.; Chowdhury, K.; Knoch, K. P.; Weitz, J.; Grutzmann, R.; Pilarsky, C.; Solimena, M.; Kersting, S.

10.1101/233098 — cell biology — Posted on 2018-08-07

1964 Human noise blindness drives suboptimal cognitive inference

Herce Castanon, S.; Bang, D.; Moran, R.; Ding, J.; Egner, T.; Summerfield, C.

10.1101/268045 — neuroscience — Posted on 2018-08-07

1965 Discrete or indiscrete? Redefining the colour polymorphism of the land snail Cepaea nemoralis

Davison, A.; Jackson, H. J.; Murphy, E. W.; Reader, T.

10.1101/383042 — evolutionary biology — Posted on 2018-08-07

1966 Statistical significance of cluster membership for determination of cell identities in single cell genomics

Chung, N. C.

10.1101/248633 — bioinformatics — Posted on 2018-08-07

1967 Knock-in rats expressing Cre and Flp recombinases at the Parvalbumin locus.

Yu, J. Y.; Pettibone, J.; Guo, C.; Zhang, S.; Saunders, T.; Hughes, E.; Filipiak, W.; Zeidler, M.; Bender, K.; Hopf, F.; Smyth, C.; Kharazia, V.; Kiseleva, A.; Davidson, T.; Frank, L.; Berke, J.

10.1101/386474 — neuroscience — Posted on 2018-08-07

1968 EGFR confers exquisite specificity of Wnt9a-Fzd9b signaling in hematopoietic stem cell development

Grainger, S.; Nguyen, N.; Richter, J.; Setayesh, J.; Lonquich, B.; Oon, C. H.; Wozniak, J. M.; Barahona, R.; Kamei, C. N.; Houston, J.; Carrillo-Terrazas, M.; Drummond, I. A.; Gonzalez, D.; Willert, K.; Traver, D.

10.1101/387043 — developmental biology — Posted on 2018-08-07

1969 Excitable dynamics of Ras triggers self-organized PIP3 signaling for spontaneous cell migration

Fukushima, S.; Matsuoka, S.; Ueda, M.

10.1101/356105 — cell biology — Posted on 2018-08-07

1970 Model neuron response statistics to natural images

Iyer, A. V.; Burge, J.

10.1101/387183 — neuroscience — Posted on 2018-08-07

1971 TP promotes malignant progression in hepatocellular carcinoma through pentose Warburg effect

Sun, T.; Zhang, Q.; Qin, Y.; Zhao, J.; Tang, Y.; Hu, X.; Zhong, W.-l.; Li, M.; Zong, S.; Li, M.; Tao, H.; Zhang, Z.; Chen, S.; Liu, H.-j.; Yang, L.; Zhou, H.; Liu, Y.-r.; Yang, C.

10.1101/386706 — cell biology — Posted on 2018-08-07

1972 A randomised controlled trial of an Intervention to Improve Compliance with the ARRIVE guidelines (IICARus)

Hair, K.; Macleod, M. R.; Sena, E. S.; The IICARus Collaboration,

10.1101/370874 — scientific communication and education — Posted on 2018-08-07

1973 Structure of the Macrobrachium rosenbergii Nodavirus: A new genus within the Nodaviridae?

Ho, K. L.; Gabrielsen, M.; Beh, P. L.; Kueh, C. L.; Qiu Xian, T.; Streetley, J.; Tan, W. S.; Bhella, D.

10.1101/386888 — microbiology — Posted on 2018-08-07

1974 Mycobacteria-specific CD4+IFN-γ+ cell expresses naïve-surface markers and confers superior protection against tuberculosis infection compared to central and effector memory CD4+ T cell subsets

Chatterjee, S.; Yuan, J.; Tenant, J.; Pacatte, T.; Eickhoff, C.; Blazevic, A.; Hoft, D.

10.1101/384784 — immunology — Posted on 2018-08-07

1975 A Key For Hypoxia Genetic Adaptation In Alpaca Could Be A HIF1A Truncated bHLH Protein Domain

Figueroa, F.; Moraga, D.; Moraga, F.

10.1101/386987 — genetics — Posted on 2018-08-07

1976 Predicting cell-cycle expressed genes identifies canonical and non-canonical regulators of time-specific expression in Saccharomyces cerevisiae

Panchy, N. L.; Lloyd, J.; Shiu, S.-H.

10.1101/387050 — genetics — Posted on 2018-08-07

1977 EGFR confers exquisite specificity of Wnt9a-Fzd9b signaling in hematopoietic stem cell development

Grainger, S.; Nguyen, N.; Richter, J.; Setayesh, J.; Lonquich, B.; Oon, C. H.; Wozniak, J. M.; Barahona, R.; Kamei, C. N.; Houston, J.; Carrillo-Terrazas, M.; Drummon, I. A.; Gonzalez, D.; Willert, K.; Traver, D.

10.1101/387043 — developmental biology — Posted on 2018-08-07

1978 The endosomal sorting adaptor HD-PTP is required for ephrin-B:EphB signalling in cell collapse and motor axon guidance

Lahaie, S.; Morales, D.; Bagci, H.; Hamoud, N.; Castonguay, C.-E.; Kazan, J. M.; Desrochers, G.; Klar, A.; Gingras, A.-C.; Pause, A.; Cote, J.-F.; Kania, A.

10.1101/386631 — cell biology — Posted on 2018-08-07

1979 Evaluating cell lines and organoids as models for metastatic cancer through integrative analysis of open genomic data

Liu, K.; Newbury, P.; Glicksberg, B.; Zeng, W. Z.; Andrechek, E.; Chen, B.

10.1101/337287 — bioinformatics — Posted on 2018-08-07

1980 Molecular analysis of Drosophila melanogaster B chromosomes reveals their origin, composition, and structure

Hanlon, S. L.; Miller, D. E.; Eche, S.; Hawley, R. S.

10.1101/386995 — genetics — Posted on 2018-08-07

1981 Ena/VASP processive elongation is modulated by avidity on actin filaments bundled by the filopodia crosslinker fascin

Harker, A. J.; Katkar, H. H.; Bidone, T. C.; Aydin, F.; Voth, G. A.; Applewhite, D. A.; Kovar, D. R.

10.1101/386961 — cell biology — Posted on 2018-08-07

1982 Local adaptation insights from genomics and ecophysiology of a neotropical mangrove

Cruz, M. V.; Mori, G. M.; Müller, C. S.; Silva, C. C.; Oh, D.-H.; Dassanayake, M.; Zucchi, M. I.; Oliveira, R. S.; de Souza, A.

10.1101/378612 — plant biology — Posted on 2018-08-07

1983 A retrieved context model of the emotional modulation of memory

Talmi, D.; Lohnas, L.; Daw, N.

10.1101/175653 — neuroscience — Posted on 2018-08-07

1984 Neural underpinnnings of auditory salience in natural soundscapes

Huang, N.; Elhilali, M.

10.1101/376525 — neuroscience — Posted on 2018-08-07

1985 Integrated ‘omic’ analyses provide evidence that a Ca. Accumulibacter phosphatis strain performs denitrification under micro-aerobic conditions

Camejo, P. Y.; Oyserman, B. O.; McMahon, K. D.; Noguera, D. R.

10.1101/386516 — microbiology — Posted on 2018-08-07

1986 Genome Wide Meta-Analysis identifies new loci associated with cardiac phenotypes and uncovers a common genetic signature shared by heart function and Alzheimer’s disease

Saez, M. E.; Gonzalez-Perez, A.; Hernandez-Olasagarre, B.; Bea, A.; Moreno-Grau, S.; de Rojas, I.; Monte, G.; Orellana, A.; Valero, S.; Comella, J. X.; Sanchis, D.; Ruiz, A.

10.1101/386680 — genetics — Posted on 2018-08-07

1987 Sex overrides mutation in Escherichia coli colonizing the gut

Frazao, N.; Sousa, A.; Lassig, M.; Gordo, I.

10.1101/384875 — evolutionary biology — Posted on 2018-08-07

1988 Fibroblasts and alectinib switch the evolutionary games that non-small cell lung cancer plays

Kaznatcheev, A.; Peacock, J.; Basanta, D.; Marusyk, A.; Scott, J. G.

10.1101/179259 — cancer biology — Posted on 2018-08-07

1989 Inferring metabolite interactomes via molecular structure informed Bayesian graphical model selection with an application to coronary artery disease

Trainor, P. J.; Mitchell, J. M.; Carlisle, S. M.; Moseley, H. N. B.; DeFilippis, A. P.; Rai, S. N.

10.1101/386409 — systems biology — Posted on 2018-08-07

1990 Camphor white oil induces tumor regression through cytotoxic T cell-dependent mechanisms

Moayedi, Y.; Greenberg, S. A.; Jenkins, B. A.; Marshall, K. L.; Dimitrov, L. V.; Nelson, A. M.; Owens, D. M.; Lumpkin, E. A.

10.1101/386789 — physiology — Posted on 2018-08-07

1991 Shared genetic aetiology between cognitive performance and brain activations in language and math tasks

Le Guen, Y.; Amalric, M.; Pinel, P.; Pallier, C.; Frouin, V.

10.1101/386805 — neuroscience — Posted on 2018-08-07

1992 Zika viruses of both African and Asian lineages cause fetal harm in a vertical transmission model

Jaeger, A.; Murrieta, R.; Goren, L.; Crooks, C.; Moriarty, R.; Weiler, A.; Rybarczyk, S.; Semler, M.; Huffman, C.; Mejia, A.; Simmons, H.; Fritsch, M.; Osorio, J.; O'Connor, S.; Ebel, G.; Friedrich, T.; Aliota, M.

10.1101/387118 — microbiology — Posted on 2018-08-07

1993 eQTL of KCNK2 regionally influences the brain sulcal widening: evidence from 15,597 UK Biobank participants with neuroimaging data

Le Guen, Y.; Philippe, C.; Riviere, D.; Lemaitre, H.; Grigis, A.; Fischer, C.; Dehaene-Lambertz, G.; Mangin, J.-F.; Frouin, V.

10.1101/386821 — genetics — Posted on 2018-08-07

1994 Neuropeptides required for Drosophila development under nutritional stress are regulated by the ER-Ca2+ sensor STIM

M, M.; Wegener, C.; Hasan, G.

10.1101/386649 — developmental biology — Posted on 2018-08-07

1995 Anti-mutagenic and synergistic cytotoxic effect of cisplatin and Honey Bee venom on 4T1 invasive mammary carcinoma cell line

Shiassi Arani, F.; Karimzadeh, L.; Ghafoori, M.; Nabiuni, M.

10.1101/168542 — pharmacology and toxicology — Posted on 2018-08-07

1996 FUS/TLS undergoes calcium-mediated nuclear egress during excitotoxic stress and is required for Gria2 mRNA processing

Tischbein, M.; Baron, D.; Lin, Y.-C.; Gall, K.; Landers, J.; Fallini, C.; Bosco, D.

10.1101/386870 — neuroscience — Posted on 2018-08-07

1997 Dysbiosis of the Biomphalaria glabrata vector snail microbiota following infection by Schistosoma parasites

Portet, A.; Toulza, E.; Lokmer, A.; Huot, C.; Duval, D.; Galinier, R.; Gourbal, B.

10.1101/386623 — microbiology — Posted on 2018-08-07

1998 GT-TS: Experimental design for maximizing cell type discovery in single-cell data

Dumitrascu, B.; Feng, K.; Engelhardt, B. E.

10.1101/386540 — genomics — Posted on 2018-08-07

1999 An Evolutionarily Conserved piRNA-producing Locus Required for Male Mouse Fertility

Wu, P.-H.; Fu, Y.; Cecchini, K.; Ozata, D. M.; Weng, Z.; Zamore, P. D.

10.1101/386201 — genetics — Posted on 2018-08-07

2000 Discrete or indiscrete? Redefining the colour polymorphism of the land snail Cepaea nemoralis

Davison, A.; Jackson, H. J.; Murphy, E. W.; Reader, T.

10.1101/383042 — evolutionary biology — Posted on 2018-08-07

2001 Biogeographic study of human gut associated crAssphage suggests impacts from industrialization and recent expansion.

Honap, T. P.; Sankaranarayanan, K.; Schnorr, S. L.; Ozga, A. T.; Warinner, C.; Lewis, C. M.

10.1101/384677 — evolutionary biology — Posted on 2018-08-07

2002 Adaptive evolution of animal proteins over development: support for the Darwin selection opportunity hypothesis of Evo-Devo

Liu, J.; Robinson-Rechavi, M.

10.1101/161711 — evolutionary biology — Posted on 2018-08-07

2003 Assessing placental maturity through histological and transcriptomic analyses in idiopathic spontaneous preterm birth

Brockway, H. M.; Jones, H. N.; Ackerman, W. E.; Buhimschi, I. A.; Buhimschi, C. S.; Kallapur, S. G.; Muglia, L. J.

10.1101/386185 — developmental biology — Posted on 2018-08-07

2004 Calcium negatively regulates secretion from dense granules in Toxoplasma gondii.

Katris, N. J.; McFadden, G. I.; van Dooren, G. G.; Waller, R. F.

10.1101/386722 — cell biology — Posted on 2018-08-07

2005 AICM: A Genuine Framework for Correcting Inconsistency Between Large Pharmacogenomics Datasets

Hu, Z. T.; Ye, Y.; Newbury, P.; Huang, H.; Chen, B.

10.1101/386896 — bioinformatics — Posted on 2018-08-07

2006 Protein-level assembly increases protein sequence recovery from metagenomic samples manyfold

Steinegger, M.; Mirdita, M.; Soding, J.

10.1101/386110 — bioinformatics — Posted on 2018-08-07

2007 Human pluripotent stem cell-derived brain pericyte-like cells induce blood-brain barrier properties

Stebbins, M. J.; Gastfriend, B. D.; Canfield, S. G.; Lee, M.-S.; Richards, D.; Faubion, M. G.; Li, W.-J.; Daneman, R.; Palecek, S. P.; Shusta, E. V.

10.1101/387100 — neuroscience — Posted on 2018-08-07

2008 Cortex-wide neural interfacing via transparent polymer skulls

10.1101/387142 — neuroscience — Posted on 2018-08-07

2009 Quantitative synapse analysis for cell-type specific connectomics

Kuljis, D. A.; Zemoura, K.; Telmer, C. A.; Lee, J.; Park, E.; Ackerman, D. S.; Xu, W.; Watkins, S. C.; Arnold, D. B.; Bruchez, M. P.; Barth, A. L.

10.1101/386912 — neuroscience — Posted on 2018-08-07

2010 Knock-in rats expressing Cre and Flp recombinases at the Parvalbumin locus.

Yu, J. Y.; Pettibone, J.; Guo, C.; Zhang, S.; Saunders, T.; Hughes, E.; Filipiak, W.; Zeidler, M.; Bender, K.; Hopf, F.; Smyth, C.; Kharazia, V.; Kiseleva, A.; Davidson, T.; Frank, L.; Berke, J.

10.1101/386474 — neuroscience — Posted on 2018-08-07

2011 Directed exploration in the Iowa Gambling Task: model-free and model-based analyses in a large dataset of young and old healthy participants

Ligneul, R.

10.1101/387019 — neuroscience — Posted on 2018-08-07

2012 Out with the old and in with the new: The role of intolerance of uncertainty in reversal of threat and safety

Morriss, J.; Saldarini, F.; Chapman, C.; Pollard, M.; van Reekum, C. M.

10.1101/386797 — neuroscience — Posted on 2018-08-07

2013 Transcriptome analysis reveals negative correlation between transcripts of mitochondrial genes and L1HS, and positive correlation between KRAB-ZFPs and older LINE elements in normal somatic tissue

Chung, N.; Jonaid, G. M.; Quinton, S.; Ross, A.; Alberto, A.; Clymer, C.; Churchill, D.; Navarro Leija, O.; Han, M. V.

10.1101/385062 — genomics — Posted on 2018-08-07

2014 Pseudogenes in the mouse lineage: transcriptional activity and strain-specific history

Sisu, C.; Muir, P.; Frankish, A.; Fiddes, I.; Diekhans, M.; Thybert, D.; Odom, D.; Flicek, P.; Keane, T.; Hubbard, T.; Harrow, J.; Gerstein, M.

10.1101/386656 — genomics — Posted on 2018-08-07

2015 Investigating Coordinated Architectures Across Clusters in Integrative Studies: a Bayesian Two-Way Latent Structure Model

Swanson, D.; Lien, T.; Bergholtz, H.; Sorlie, T.; Frigessi, A.

10.1101/387076 — bioinformatics — Posted on 2018-08-07

2016 Featherweight long read alignment using partitioned reference indexes

Gamaarachchi, H.; Parameswaran, S.; Smith, M.

10.1101/386847 — bioinformatics — Posted on 2018-08-07

2017 A chemical biology view of bioactive small molecules and a binder-based approach to connect biology to precision medicines

Schreiber, S.

10.1101/386904 — biochemistry — Posted on 2018-08-07

2018 Individual differences in reading comprehension and off-task thought relate to perceptually-coupled and decoupled cognition

Zhang, M.; Savill, N.; Margulies, D. S.; Smallwood, J.; Jefferies, E.

10.1101/387035 — neuroscience — Posted on 2018-08-07

2019 Genome-wide association study of multiple yield components in a diversity panel of polyploid sugarcane (Saccharum spp.)

Yang, X.; Luo, Z.; Todd, J.; Sood, S.; Wang, J.

10.1101/387001 — genomics — Posted on 2018-08-07

2020 Evolution of phenotypic plasticity in response to ethanol between sister species with different ecological histories (Drosophila melanogaster and D. simulans)

Signor, S.; Nuzhdin, S.

10.1101/386334 — evolutionary biology — Posted on 2018-08-07

2021 Inducible formation of leading cells driven by CD44 switching gives rise to collective invasion

Yang, C.; Cao, M.; Liu, Y.; He, Y.; Du, Y.; Zhang, G.; Gao, F.

10.1101/387092 — cancer biology — Posted on 2018-08-07

2022 Blocking the Necroptosis Pathway Decreases RPE and Photoreceptor Damage Induced by NaIO3

Roh, M.; Lin, H.; Matsumoto, H.; Atik, A.; Bouzika, P.; Alhatem, A.; Miller, J.; Vavvas, D.

10.1101/387068 — biochemistry — Posted on 2018-08-07

2023 Demystifying excessively volatile human learning: A Bayesian persistent prior and a neural approximation

Ryali, C. K.; Reddy, G.; Yu, A. J.

10.1101/077719 — neuroscience — Posted on 2018-08-07

2024 Domestication and temperature modulate gene expression signatures and growth in the Australasian snapper Chrysophrys auratus

Wellenreuther, M.; Le Luyer, J.; Cook, D.; Ritchie, P. A.; Bernatchez, L.

10.1101/387084 — evolutionary biology — Posted on 2018-08-07

2025 NAD consumption by PARP1 in response to DNA damage triggers metabolic shift critical for damaged cell survival

Murata, M.; Kong, X.; Moncada, E.; Chen, Y.; Wang, P. H.; Berns, M. W.; Yokomori, K.; Digman, M.

10.1101/375212 — cell biology — Posted on 2018-08-07

2026 A survey of influenza subtypes in olive baboons in selected areas in Kenya

Bunuma, E.; Ochola, L.; Nyerere, A.

10.1101/380345 — molecular biology — Posted on 2018-08-07

2027 Phylogenetic barriers to horizontal transfer of antimicrobial peptide resistance genes in the human gut microbiota

Kintses, B.; Mehi, O. K.; Ari, E.; Szamel, M.; Györkei, A.; Jangir, P. K.; Nagy, I.; Pal, F.; Fekete, G.; Tengölics, R.; Nyerges, A.; Liko, I.; Balint, B.; Vasarhelyi, B. M.; Bustamante, M.; Papp, B.; Pal, C.

10.1101/385831 — microbiology — Posted on 2018-08-07

2028 Modelling cancer immunomodulation using epithelial organoid cultures

Bar-Ephraim, Y. E.; Kretzschmar, K.; Asra, P.; de Jongh, E.; Boonekamp, K. E.; Drost, J.; van Gorp, J.; Pronk, A.; Smakman, N.; Gan, I. J.; Sebestyen, Z.; Kuball, J. H.; Vries, R. G.; Clevers, H.

10.1101/377655 — cancer biology — Posted on 2018-08-07

2029 Familiarity increases aggressiveness among clonal fish.

Doran, C.; Bierbach, D.; Laskowski, K. L.

10.1101/386714 — animal behavior and cognition — Posted on 2018-08-07

2030 Retrospective cues mitigate information loss in human cortex during working memory storage

Ester, E.; Nouri, A.; Rodriguez, L.

10.1101/351544 — neuroscience — Posted on 2018-08-07

2031 Testing the possibility of model-based Pavlovian control of attention to threat

Talmi, D.; Slapkova, M.; Wieser, M. J.

10.1101/288027 — neuroscience — Posted on 2018-08-07

2032 Efficient single-copy HDR by 5’ modified long dsDNA donors

Gutierrez-Triana, J. A.; Tavhelidse, T.; Thumberger, T.; Thomas, I.; Wittbrodt, B.; Kellner, T.; Anlas, K.; Tsingos, E.; Wittbrodt, J.

10.1101/348243 — genetics — Posted on 2018-08-07

2033 Accurate protein-folding transition-path statistics from a simple free-energy landscape

Jacobs, W. M.; Shakhnovich, E. I.

10.1101/350298 — biophysics — Posted on 2018-08-07

2034 Culturing the ubiquitous freshwater actinobacterial acI lineage by supplying a biochemical ‘helper’ catalase

Kim, S.; Kang, I.; Seo, J.-H.; Cho, J.-C.

10.1101/343640 — microbiology — Posted on 2018-08-07

2035 Sexual selection and inbreeding: two efficient ways to limit the accumulation of deleterious mutations

Noel, E.; Fruitet, E.; Lelaurin, D.; Bonel, N.; Segard, A.; Sarda, V.; Jarne, P.; David, P.

10.1101/273367 — evolutionary biology — Posted on 2018-08-07

2036 A systems and treatment perspective of models of influenza virus-induced host responses

Mochan, E.; Ackerman, E. E.; Shoemaker, J. E.

10.1101/368241 — synthetic biology — Posted on 2018-08-07

2037 Improving Whole-Brain Neural Decoding of fMRI with Domain Adaptation

Zhou, S.; Cox, C. R.; Lu, H.

10.1101/375030 — neuroscience — Posted on 2018-08-07

2038 Fndc3a (Fibronectin Domain Containing Protein 3A) influences median fin fold development and caudal fin regeneration in zebrafish by ECM alteration.

Liedtke, D.; Orth, M.; Meissler, M.; Geuer, S.; Knaup, S.; Koblitz, I.; Klopocki, E.

10.1101/386813 — developmental biology — Posted on 2018-08-07

2039 Glycosyltransferase homologs prevent promiscuous cell aggregation and promote multicellular development in the choanoflagellate S. rosetta

Wetzel, L.; Levin, T.; Hulett, R. E.; Chan, D.; King, G.; Aldayafleh, R.; Booth, D.; Sigg, M. A.; King, N.

10.1101/384453 — genetics — Posted on 2018-08-07

2040 Application of an Interpretable Classification Model on Early Folding Residues during Protein Folding

Bittrich, S.; Kaden, M.; Leberecht, C.; Kaiser, F.; Villmann, T.; Labudde, D.

10.1101/381483 — bioinformatics — Posted on 2018-08-07

2041 Establishing Synthesis Pathway-Host Compatibility viaEnzyme Solubility

Amin, S. A.; Endalur Gopinarayanan, V.; Nair, N. U.; Hassoun, S.

10.1101/386144 — synthetic biology — Posted on 2018-08-07

2042 The sunlit microoxic niche of the archaeal eukaryotic ancestor comes to light

Bulzu, P.-A.; Andrei, A.-S.; Salcher, M. M.; Mehrshad, M.; Inoue, K.; Kandori, H.; Beja, O.; Ghai, R.; Banciu, H.

10.1101/385732 — microbiology — Posted on 2018-08-07

2043 Enhanced axonal Neuregulin-1 type-III signaling ameliorates disease severity in a CMT1B mouse model

Scapin, C.; Ferri, C.; Pettinato, E.; Zambroni, D.; Bianchi, F.; Belin, S.; Del Carro, U.; Mitro, N.; Caruso, D.; Pellegatta, M.; Taveggia, C.; Schwab, M. H.; Nave, K.-A.; Feltri, M. L.; Wrabetz, L.; D'Antonio, M.

10.1101/386730 — neuroscience — Posted on 2018-08-07

2044 Nanobody-antigen catch-bond reveals NK cell mechanosensitivity

Gonzalez, C.; Chames, P.; Kerfelec, B.; Baty, D.; Robert, P.; Limozin, L.

10.1101/386094 — biophysics — Posted on 2018-08-07

2045 iProteinDB: an integrative database of Drosophila post-translational modifications

Hu, Y.; Sopko, R.; Chung, V.; Studer, R. A.; Landry, S. D.; Liu, D.; Rabinow, L.; Gnad, F.; Beltrao, P.; Perrimon, N.

10.1101/386268 — bioinformatics — Posted on 2018-08-07

2046 Locomotion-dependent remapping of distributed cortical networks

Clancy, K.; Orsolic, I.; Mrsic-Flogel, T.

10.1101/386375 — neuroscience — Posted on 2018-08-07

2047 Transcriptional regulation of voltage-gated sodium channels contributes to GM-CSF induced pain

Zhang, F.; Wang, Y.; Zhang, D.; Fan, X.; Han, H.; Du, X.; Gamper, N.; Zhang, H.

10.1101/386698 — neuroscience — Posted on 2018-08-07

2048 Neuregulin 1 type III reduces severity in a mouse model of Congenital Hypomyelinating Neuropathy

Sophie, B.; Ornaghi, F.; Shackleford, G.; Wang, J.; Scapin, C.; Lopez-Anido, C.; Silvestri, N.; Robertson, N.; Williamson, C.; Ishii, A.; Taveggia, C.; Svaren, J.; Bansal, R.; Schwab, M. H.; Nave, K.-A.; Fratta, P.; Poitelon, Y.; D'Antonio, M.; Feltri, M. L.; Wrabetz, L.

10.1101/386748 — neuroscience — Posted on 2018-08-07

2049 Proliferation of Superficial Neuromasts During Lateral Line Development in the Round Goby, Neogobius melanostomus

Dickson, J.; Janssen, J. A.

10.1101/386169 — evolutionary biology — Posted on 2018-08-07

2050 Alterations in sperm long RNA contribute to the epigenetic inheritance of the effects of postnatal trauma

Gapp, K.; van Steenwyk, G.; Germain, P.-L.; Matsushima, W.; Rudolph, K.; Manuella, F.; Roszkowski, M.; Vernaz, G.; Gosh, T.; Pelczar, P.; Mansuy, I. M.; Miska, E.

10.1101/386037 — developmental biology — Posted on 2018-08-07

2051 A Striatal interneuron circuit for continuous target pursuit

Kim, N.; Li, H. E.; Hughes, R. N.; Gallegos, D.; West, A.; Kim, I. H.; Yin, H.

10.1101/386490 — neuroscience — Posted on 2018-08-07

2052 The splicing regulator Prp31 prevents retinal degeneration in Drosophila by regulating Rhodopsin levels

Knust, E.; Lehmann, M.; Hebbar, S.; Behrens, S.; Leng, W.; Yuan, M.; Winkler, S.

10.1101/386433 — genetics — Posted on 2018-08-07

2053 Evolution of phenotypic plasticity in response to ethanol between sister species with different ecological histories (Drosophila melanogaster and D. simulans)

Signor, S.; Nuzhdin, S.

10.1101/386334 — evolutionary biology — Posted on 2018-08-07

2054 A new model on DNA structure and thermal denaturation

Luo, L.; Yang, G.

10.1101/386524 — biophysics — Posted on 2018-08-07

2055 Parallelized analysis of spatial gene expression patterns by database integration

Miyamoto, D.; Ikeno, H.; Okamura-Oho, Y.; Sato, A.; Furuichi, T.; Okumura, Y.; Yamaguchi, Y.; Kanzaki, R.

10.1101/386086 — neuroscience — Posted on 2018-08-07

2056 Lateral gene transfer shapes the distribution of RuBisCO among Candidate Phyla Radiation bacteria and DPANN archaea

Jaffe, A. L.; Castelle, C. J.; Dupont, C. L.; Banfield, J. F.

10.1101/386292 — microbiology — Posted on 2018-08-07

2057 Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis

Lees, J.; Ferwerda, B.; Kremer, P. H.; Wheeler, N. E.; Valls Seron, M.; Croucher, N. J.; Gladstone, R. A.; Bootsma, H. J.; Rots, N.; Wijmega-Monsuur, A. J.; Sanders, E. A.; Trzcinski, K.; Wyllie, A. L.; Zwinderman, A. H.; van den Berg, L. H.; van Rheenen, W.; Veldink, J. H.; Harboe, Z. B.; Lundbo, L. F.; de Groot, L. C.; van Schoor, N. M.; van der Velde, N.; Ängquist, L. H.; Sorensen, T. I.; Nohr, E. A.; Mentzer, A. J.; Mills, T. C.; Knight, J. C.; du Plessis, M.; Nzenze, S.; Weiser, J. N.; Parkhill, J.; Madhi, S.; Benfield, T.; von Gottberg, A.; van der Ende, A.; Brouwer, M. C.; Barrett, J.

10.1101/386078 — genomics — Posted on 2018-08-07

2058 Allele-specific RNA imaging shows that allelic imbalances can arise in tissues through transcriptional bursting

Symmons, O.; Chang, M.; Mellis, I.; Kalish, J. M.; Bartolomei, M. S.; Raj, A.

10.1101/386359 — genetics — Posted on 2018-08-07

2059 Costs and benefits of mating with fertilized females in a species with first male sperm precedence

Rodrigues, L. R.; Figueiredo, A. R.; Van Leeuwen, T.; Olivieri, I.; Magalhaes, S.

10.1101/386045 — evolutionary biology — Posted on 2018-08-07

2060 Extracting allelic read counts from 250,000 human sequencing runs in Sequence Read Archive

Tsui, B. Y.; Dow, M.; Skola, D.; Carter, H.

10.1101/386441 — bioinformatics — Posted on 2018-08-07

2061 Development of plant regeneration and Agrobacterium tumefaciens-mediated transformation methodology for Physalis pruinosa

Swartwood, K.; Van Eck, J. M.

10.1101/386235 — plant biology — Posted on 2018-08-07

2062 Neuronal distribution across the cerebral cortex of the marmoset monkey (Callithrix jacchus)

Atapour, N.; Majka, P.; Hutler Wolkowicz, I.; Malamanova, D.; Worthy, K. H.; Rosa, M. G. P.

10.1101/385971 — neuroscience — Posted on 2018-08-07

2063 Identification, Genotyping, and Pathogenicity of Trichosporon spp. Isolated from Giant Pandas

Ma, X.; Jiang, Y.; Wang, C. d.; Gu, Y.; CAO, S.; Huang, X.; Wen, Y.; Zhao, Q.; Wu, R.; Wen, X.; Yan, Q. g.; Han, X.; Zuo, Z.; Deng, J.; Ren, Z.; Yu, S.; Shen, L.; Zhong, Z.; Peng, G.; Liu, H.; Zhou, Z.

10.1101/386581 — microbiology — Posted on 2018-08-07

2064 Metaepigenomic analysis reveals the unexplored diversity of DNA methylations in an environmental prokaryotic community

Hiraoka, S.; Okazaki, Y.; Anda, M.; Toyoda, A.; Nakano, S.-i.; Iwasaki, W.

10.1101/380360 — microbiology — Posted on 2018-08-07

2065 Two-step concentration of complex water samples for the detection of viruses

Farkas, K.; McDonald, J. E.; Malham, S. K.; Jones, D. L.

10.1101/386060 — microbiology — Posted on 2018-08-07

2066 Genome Wide Study of Tardive Dyskinesia in Schizophrenia

Lam, M.; Lim, K.; Tay, J.; Karlsson, N.; Deshpande, S. N.; Thelma, B. K.; Ozaki, N.; Inada, T.; Sim, K.; Chong, S.-A.; Liu, J.; Lee, J.

10.1101/386227 — genomics — Posted on 2018-08-07

2067 Strand Orientation Bias Detector (SOBDetector) to remove artifacts from sequencing data of formalin fixed samples

Diossy, M.; Sztupinszki, Z.; Krzystanek, M.; Pedersen, A. G.; Eklund, A. C.; Csabai, I.; Szallasi, Z.

10.1101/386417 — bioinformatics — Posted on 2018-08-07

2068 Can patients with cerebellar disease switch learning mechanisms to reduce their adaptation deficits?

Wong, A. L.; Marvel, C. L.; Taylor, J. A.; Krakauer, J. W.

10.1101/386466 — neuroscience — Posted on 2018-08-07

2069 Decision-making through integration of sensory evidence at prolonged timescales

Waskom, M. L.; Kiani, R.

10.1101/385989 — neuroscience — Posted on 2018-08-07

2070 Extensive Diversity of RNA Viruses in Australian Ticks

Harvey, E.; Rose, K.; Eden, J.-S.; Lo, N.; Abeyasuriya, T.; Shi, M.; Doggett, S. L.; Holmes, E. C.

10.1101/386573 — microbiology — Posted on 2018-08-07

2071 A negative role for the interleukin-2-inducible T-cell kinase (ITK) in human Foxp3+ Treg differentiation

Mamontov, P.; Eberwine, R. A.; Perrigoue, J.; Das, A.; Friedman, J. R.; Mora, J. R.

10.1101/386508 — immunology — Posted on 2018-08-07

2072 One species, two genomes: A critical assessment of inter isolate variation and identification of assembly incongruence in Haemonchus contortus

Wintersinger, J.; Mariene, G. M.; Wasmuth, J.

10.1101/384008 — genomics — Posted on 2018-08-07

2073 Neuropsychiatric Phenotypes in 3q29 Deletion Syndrome

Pollak, R. M.; Murphy, M. M.; Epstein, M. P.; Zwick, M. E.; Klaiman, C.; Saulnier, C. A.; Mulle, J. G.

10.1101/386243 — genetics — Posted on 2018-08-07

2074 The ESCRT-III proteins IST1 and CHMP1B assemble around nucleic acids

Talledge, N.; McCullough, J.; Wenzel, D.; Nguyen, H. C.; Lalonde, M. S.; Bajorek, M.; Skalicky, J.; Frost, A.; Sundquist, W. I.

10.1101/386532 — biochemistry — Posted on 2018-08-07

2075 Dendritic spine geometry and spine apparatus organization govern the spatiotemporal dynamics of calcium

Bell, M.; Bartol, T.; Sejnowski, T.; Rangamani, P.

10.1101/386367 — systems biology — Posted on 2018-08-07

2076 The crossover function of MutSγ is activated via Cdc7-dependent stabilization of Msh4

10.1101/386458 — genetics — Posted on 2018-08-07

2077 Single-cell transcriptome analysis of human, marmoset and mouse embryos reveals common and divergent features of preimplantation development

Boroviak, T.; Stirparo, G. G.; Dietmann, S.; Herraez, I. H.; Mohammed, H.; Reik, W.; Smith, A.; Sasaki, E.; Nichols, J.; Bertone, P.

10.1101/385815 — developmental biology — Posted on 2018-08-07

2078 Multi-modal regulation of C. elegans hermaphrodite spermatogenesis by the GLD-1-FOG-2 complex

Hu, S.; Ryan, L. E.; Kaymak, E.; Freeberg, L.; Lo, T.-W.; Kuersten, S.; Ryder, S. P.; Haag, E. S.

10.1101/386250 — developmental biology — Posted on 2018-08-07

2079 Foxp1 controls neural stem cell competence and bias towards deep layer cortical fate.

Pearson, C. A.; Moore, D.; Tucker, H.; Dekker, J.; Hu, H.; Miquelajauregui, A.; Novitch, B.

10.1101/386276 — developmental biology — Posted on 2018-08-07

2080 ELYS coordinates NF-κB pathway dynamics during development in Drosophila

Mehta, S. J. K.; Kumar, V.; Mishra, R. K.

10.1101/386607 — cell biology — Posted on 2018-08-07

2081 Functional and structural resilience of the active site loop in the evolution of Plasmodium lactate dehydrogenase.

Wirth, J. D.; Boucher, J. I.; Jacobowitz, J. R.; Classen, S.; Theobald, D.

10.1101/386029 — biochemistry — Posted on 2018-08-07

2082 An assay for de novo kinetochore assembly reveals a key role for the CENP-T pathway in budding yeast

Lang, J.; Barber, A.; Biggins, S.

10.1101/381897 — biochemistry — Posted on 2018-08-07

2083 How many individuals share a mitochondrial genome?

Andersen, M. M.; Balding, D. J.

10.1101/374686 — genetics — Posted on 2018-08-07

2084 A Bayesian sequential learning framework to parameterise continuum models of melanoma invasion into human skin

Browning, A.; Haridas, P.; Simpson, M.

10.1101/284612 — biophysics — Posted on 2018-08-07

2085 SAFE-clustering: Single-cell Aggregated (From Ensemble) Clustering for Single-cell RNA-seq Data

Yang, Y.; Huh, R.; Culpepper, H. W.; Lin, Y.; Love, M. I.; Li, Y.

10.1101/215723 — bioinformatics — Posted on 2018-08-06

2086 Rapid, noninvasive, and unsupervised detection of sleep/wake using piezoelectric monitoring for pharmacological studies in narcoleptic mice

Black, S. W.; Sun, J. D.; Laihsu, A.; Kimura, N.; Santiago, P.; Donohue, K. D.; O'Hara, B. F.; Bersot, R.; Humphries, P. S.

10.1101/226522 — neuroscience — Posted on 2018-08-06

2087 Transforming summary statistics from logistic regression to the liability scale: application to genetic and environmental risk scores

Gillett, A. C.; Vassos, E.; Lewis, C.

10.1101/385740 — epidemiology — Posted on 2018-08-06

2088 Homology Directed Repair by Cas9:Donor Co-localization in Mammalian Cells

Roche, P. J.; Gytz, H.; Hussain, F.; Cameron, C. J.; Paquette, D.; Blanchette, M.; Dostie, J.; Nagar, B.; Akavia, U. D.

10.1101/248179 — biochemistry — Posted on 2018-08-06

2089 The evolutionary potential of diet-dependent effects on lifespan and fecundity in a multi-parental population of Drosophila melanogaster

Ng'oma, E.; Fidelis, W.; Middleton, K.; King, E. G.

10.1101/343947 — evolutionary biology — Posted on 2018-08-06

2090 A Predictive Epilepsy Index Based on Probabilistic Classification of Interictal Spike Waveforms

Pfammatter, J. A.; Bergstrom, R. A.; Wallace, E. P.; Maganti, R. K.; Jones, M. V.

10.1101/373571 — neuroscience — Posted on 2018-08-06

2091 Single-nucleus RNA sequencing shows convergent evidence from different cell types for altered synaptic plasticity in major depressive disorder.

Nagy, C.; Maitra, M.; Suderman, M.; Theroux, J.-F.; Mechawar, N.; Ragoussis, J.; Turecki, G.

10.1101/384479 — neuroscience — Posted on 2018-08-06

2092 Addiction associated N40D mu-opioid receptor variant modulates synaptic function in human neurons

Halikere, A.; Popova, D.; Hamod, A.; Swerdel, M. R.; Moore, J. C.; Tischfield, J. A.; Hart, R. P.; Pang, Z. P.

10.1101/328898 — neuroscience — Posted on 2018-08-06

2093 Programmed genome editing of the omega-1 ribonuclease of the blood fluke, Schistosoma mansoni

10.1101/358424 — molecular biology — Posted on 2018-08-06

2094 Point of Care Diagnostic Deployment and Targeted Treatment of Antimicrobial Resistant Non-Typhoidal Salmonella: a New Mathematical Model and Cost-Benefit Analysis

Manore, C.; Graham, T.; Carr, A.; Feryn, A.; Jakhar, S.; Mukundan, H.; Callender, H.

10.1101/384933 — epidemiology — Posted on 2018-08-06

2095 Mice developing mammary tumors evolve T cell sequences shared with human breast cancer patients

Gordin, M.; Philip, H.; Zilberberg, A.; Gidoni, M.; Margalit, R.; Clouser, C.; Adams, K.; Vigneault, F.; R. Cohen, I.; Yaari, G.; Efroni, S.

10.1101/371260 — cancer biology — Posted on 2018-08-06

2096 DeepSignal: detecting DNA methylation state from Nanopore sequencing reads using deep-learning

Ni, P.; Huang, N.; Luo, F.; Wang, J.

10.1101/385849 — bioinformatics — Posted on 2018-08-06

2097 NHX-type Na+(K+)/H+ antiporter activity is required for endomembrane trafficking and ion homeostasis in Arabidopsis thaliana

Dragwidge, J. M.; Scholl, S.; Schumacher, K.; Gendall, A. R.

10.1101/382663 — plant biology — Posted on 2018-08-06

2098 Impact of Microbial Iron Oxide Reduction on the Transport of Diffusible Tracers and Non-diffusible Nanoparticles in Soils

Liang, X.; Radosevich, M.; Loeffler, F.; Schaeffer, S.; Zhuang, J.

10.1101/386128 — microbiology — Posted on 2018-08-06

2099 The genetic architecture of target-site resistance to pyrethroid insecticides in the African malaria vectors Anopheles gambiae and Anopheles coluzzii

Clarkson, C. S.; Miles, A.; Harding, N. J.; Weetman, D.; Kwiatkowski, D.; Donnelly, M.; The Anopheles gambiae 1000 Genomes Consortium,

10.1101/323980 — genomics — Posted on 2018-08-06

2100 The GalNAc-T Activation (GALA) Pathway: Drivers and Markers

Chia, J.; Tay, F.; Bard, F.

10.1101/301978 — cell biology — Posted on 2018-08-06

2101 3D images of Neuronal Adhesion Molecule Contactin-2 Reveal an Unanticipated Two-State Architecture

Lu, Z.; Lei, D.; Seshadrinathan, S.; Szwed, A.; Liu, J.; Liu, J.; Rudenko, G.; Ren, G.

10.1101/386102 — biochemistry — Posted on 2018-08-06

2102 Footprints of antigen processing boost MHC class II natural ligand binding predictions

Barra, C. M.; Alvarez, B.; Paul, S.; Sette, A.; Peters, B.; Buus, S.; Andreatta, M.; Nielsen, M.

10.1101/285767 — immunology — Posted on 2018-08-06

2103 Minimizing Structural Bias in Single-Molecule Super-Resolution Microscopy

Mazidi, H.; Lu, J.; Nehorai, A.; Lew, M. D.

10.1101/293670 — bioinformatics — Posted on 2018-08-06

2104 Efficient Zygotic Genome Editing via RAD51-Enhanced Interhomolog Repair

Wilde, J. J.; Aida, T.; Wienisch, M.; Zhang, Q.; Qi, P.; Feng, G.

10.1101/263699 — molecular biology — Posted on 2018-08-06

2105 Epithelial control of colonisation by Streptococcus pneumoniae at the human mucosal surface

Weight, C. M.; Venturini, C.; Pojar, S.; Jochems, S.; Reine, J.; Nikolaou, E.; Solorzano, C.; Noursadeghi, M.; Brown, J. S.; Ferreira, D. M.; Heyderman, R. S.

10.1101/281576 — immunology — Posted on 2018-08-06

2106 Programmed mutation of liver fluke granulin using CRISPR/Cas9 attenuates virulence of infection-induced hepatobiliary morbidity

Arunsan, P.; Ittiprasert, W.; Smout, M. J.; Cochran, C. J.; Mann, V. H.; Chaiyadet, S.; Karinshak, S. E.; Sripa, B.; Young, N. D.; Sotillo, J.; Loukas, A.; Brindley, P. J.; Laha, T.

10.1101/386219 — molecular biology — Posted on 2018-08-06

2107 mRNA localisation in endothelial cells regulates blood vessel sprouting

Costa, G.; Tarannum, N.; Herbert, S.

10.1101/374850 — developmental biology — Posted on 2018-08-06

2108 Energy expenditure and body composition changes after an isocaloric ketogenic diet in overweight and obese men: a secondary analysis of energy expenditure and physical activity

Friedman, M. I.; Appel, S.

10.1101/383752 — physiology — Posted on 2018-08-06

2109 Thought experiment: Decoding cognitive processes from the fMRI data of one individual

Wegrzyn, M.; Aust, J.; Barnstorf, L.; Gippert, M.; Harms, M.; Hautum, A.; Heidel, S.; Herold, F.; Hommel, S. M.; Knigge, A.-K.; Neu, D.; Peters, D.; Schaefer, M.; Schneider, J.; Vormbrock, R.; Zimmer, S. M.; Woermann, F. G.; Labudda, K.

10.1101/341594 — neuroscience — Posted on 2018-08-06

2110 CausalTab: PSI-MITAB 2.8 updated format for signaling data representation and dissemination

Perfetto, L.; Acencio, M. L.; Bradley, G.; Cesareni, G.; del Toro, N.; Fazekas, D.; Hermjakob, H.; Korcsmaros, T.; Kuiper, M.; laegreid, A.; Lo Surdo, P.; Lovering, R. C.; Orchard, S.; Porras, P.; Thomas, P. D.; Toure, V.; Zobolas, J.; Licata, L.

10.1101/385773 — systems biology — Posted on 2018-08-06

2111 How much fear is in anxiety?

Genewsky, A.; Albrecht, N.; Bura, S. A.; Kaplick, P. M.; Heinz, D. E.; Nussbaumer, M.; Engel, M.; Grünecker, B.; Kaltwasser, S. F.; Riebe, C. J.; Bedenk, B. T.; Czisch, M.; Wotjak, C. T.

10.1101/385823 — neuroscience — Posted on 2018-08-06

2112 The sunlit microoxic niche of the archaeal eukaryotic ancestor comes to light

Bulzu, P.-A.; Andrei, A.-S.; Salcher, M. M.; Mehrshad, M.; Inoue, K.; Kandori, H.; Beja, O.; Ghai, R.; Banciu, H.

10.1101/385732 — microbiology — Posted on 2018-08-06

2113 Adaptive metabolic strategies explain diauxic shifts and promote species coexistence

Pacciani, L.; Suweis, S.; Maritan, A.

10.1101/385724 — ecology — Posted on 2018-08-06

2114 Mini viral RNAs act as innate immune agonists during influenza virus infection

te Velthuis, A.; Long, J.; Bauer, D. L.; Fan, R.; Yen, H.-L.; Sharps, J.; Siegers, J.; Killip, M.; French, H.; Oliva-Martin, M. J.; Randall, R.; de Wit, E.; van Riel, D.; Poon, L.; Fodor, E.

10.1101/385716 — microbiology — Posted on 2018-08-06

2115 Response to Shah et al: Using high-resolution variant frequencies empowers clinical genome interpretation and enables investigation of genetic architecture

Whiffin, N.; Roberts, A.; Minikel, E. V.; Zappala, Z.; Walsh, R.; O'Donnell-Luria, A. H.; Karczewski, K.; Harrison, S. M.; Thomson, K. L.; Sage, H.; Ing, A. Y.; Barton, P. J. R.; Cook, S. A.; MacArthur, D. G.; Ware, J. S.

10.1101/384271 — genomics — Posted on 2018-08-06

2116 Triparental inheritance in Dictyostelium

Bloomfield, G.; Paschke, P.; Okamoto, M.; Stevens, T. J.; Urushihara, H.

10.1101/385708 — genetics — Posted on 2018-08-06

2117 Drug repurposing through joint learning on knowledge graphs and literature

Alshahrani, M.; Hoehndorf, R.

10.1101/385617 — bioinformatics — Posted on 2018-08-06

2118 Evolutionary landscape of mosquito viral integrations

Pischedda, E.; Scolari, F.; Valerio, F.; Carballar-Lejarazu, R.; Catapano, P. L.; Waterhouse, R. M.; Bonizzoni, M.

10.1101/385666 — evolutionary biology — Posted on 2018-08-06

2119 Oral iron exacerbates colitis and influences the intestinal microbiome

Mahalhal, A.; Williams, J. M.; Johnson, S.; Ellaby, N.; Duckworth, C. A.; Burkitt, M. D.; Liu, X.; Hold, G. L.; Campbell, B. J.; Pritchard, D. M. P.; Probert, C. S.

10.1101/385997 — physiology — Posted on 2018-08-06

2120 Altered microRNA expression profles are involved in Storage Lesions of Apheresis Platelet

Yuan, Z.; Wu, Q.; Chen, X.; Wei, Y.; no,

10.1101/386011 — molecular biology — Posted on 2018-08-06

2121 Carbon starvation-induced lipoprotein Slp directs the synthesis of catalase and expression of OxyR regulator to protect against hydrogen peroxide stress in Escherichia coli

Zhang, H.; Li, X.; Xie, Y.; Jin, J.; Liu, H.; Gao, X.; Xiong, L.

10.1101/386003 — molecular biology — Posted on 2018-08-06

2122 Combining 3D single molecule localization strategies for reproducible bioimaging

Cabriel, C.; Bourg, N.; Jouchet, P.; Dupuis, G.; Leterrier, C.; Baron, A.; Badet-Denisot, M.-A.; Vauzeilles, B.; Fort, E.; Leveque-Fort, S.

10.1101/385799 — biophysics — Posted on 2018-08-06

2123 The RopGEF KARAPPO is Essential for the Initiation of Vegetative Reproduction in Marchantia

Hiwatashi, T.; Quan, K. L.; Yasui, Y.; Takami, H.; Kajikawa, M.; Kirita, H.; Sato, M.; Wakazaki, M.; Yamaguchi, K.; Shigenobu, S.; Fukaki, H.; Mimura, T.; Yamato, K. T.; Toyooka, K.; Sawa, S.; Urano, D.; Kohchi, T.; Ishizaki, K.

10.1101/385682 — plant biology — Posted on 2018-08-06

2124 MORPHOMETRIC IDENTIFICATION OF STEM BORERS Diatraea saccharalis AND Diatraea busckella (Lepidoptera: Crambidae) IN SUGARCANE CROPS (Saccharum officinarum) IN CALDAS DEPARTMENT, COLOMBIA

Valencia Arbelaez, J. A.; Giraldo, A. S.; Villa, G. J. C.; Espinosa, L. F. V.; Guitierrez, M. R. S.

10.1101/385955 — ecology — Posted on 2018-08-06

2125 Heat stress modifies the lactational performances and the urinary metabolomic profile related to gastrointestinal microbiota of dairy goats

Contreras-Jodar, A.; Nayan, N. H.; Hamzaoui, S.; Caja, G.; Salama, A. A. K.

10.1101/385930 — systems biology — Posted on 2018-08-06

2126 Using selective lung injury to improve murine models of spatially heterogeneous lung diseases

Paris, A. J.; Guo, L.; Dai, N.; Katzen, J.; Patel, P.; Worthen, G. S.; Brenner, J. S.

10.1101/385922 — pharmacology and toxicology — Posted on 2018-08-06

2127 A prospective, observational study on conversion of Clinically Isolated Syndrome to Multiple Sclerosis during 4-year period (MS NEO study) in Taiwan

Ro, L.-S.; Yang, C.-C.; Lyu, R.-K.; Lin, K.-P.; Tsai, T.-C.; Lu, S.-R.; Huang, L.-C.; Tsai, C.-P.; Chang, K.-H.

10.1101/385898 — neuroscience — Posted on 2018-08-06

2128 Anterior fontanelle size among term neonates on the first day of life born at University of Gondar Hospital, Northwest Ethiopia

Oumer, M.; Guday, E.; Teklu, A.; Muche, A.; Mohammed Oumer, Edengenet Guday, Alemayehu Teklu, Abebe Muche,

10.1101/385906 — epidemiology — Posted on 2018-08-06

2129 Competition among Aedes aegypti larvae

Steinwascher, K.

10.1101/385914 — ecology — Posted on 2018-08-06

2130 Melatonin: The smart molecule that differentially modulates autophagy in tumor and normal placental cells

Sagrilo-Fagundes, L.; Bienvenue-Pariseault, J.; Vaillancourt, C.

10.1101/385948 — cell biology — Posted on 2018-08-06

2131 Reducing Aedes albopictus breeding sites through education: a study in urban area

Stefopoulou, A.; Balatsos, G.; Petraki, A.; LaDeau, S. L.; Papachristos, D.; Michaelakis, A.

10.1101/385872 — zoology — Posted on 2018-08-06

2132 Dopamine D1 receptor signalling differentially regulates action sequences and turning behaviour in freely moving Drosophila

Kottler, B.; Faville, R.; Bridi, J.; Hirth, F.

10.1101/385674 — neuroscience — Posted on 2018-08-06

2133 Shared neural mechanisms between imagined and perceived egocentric motion

Macauda, G.; Moisa, M.; Mast, F. W.; Ruff, C. C.; Michels, L.; Lenggenhager, B.

10.1101/385625 — neuroscience — Posted on 2018-08-06

2134 Epidemiological impact of hepatitis B vaccination in Monastir Tunisia (2000-17)

Dhouib, W.; Kacem, M.; Samia, G.; Maalel, I.; Zemni, I.; Abroug, H.; Ben Salah, A.; Chelly, S.; Djobbi, A.; Green, E.; Sriha Belguith, A.

10.1101/385880 — immunology — Posted on 2018-08-06

2135 Open-Source Food: Nutrition, Toxicology, and Availability of Wild Edible Greens in the East Bay

Stark, P.; Miller, D.; Carlson, T.; de Vasquez, K. R.

10.1101/385864 — ecology — Posted on 2018-08-06

2136 Efa6 regulates axon growth, branching and maintenance by eliminating off-track microtubules at the cortex

Qu, Y.; Hahn, I.; Lees, M.; Parkin, J.; Voelzmann, A.; Dorey, K.; Rathbone, A.; Friel, C.; Allan, V.; Okenve-Ramos, P.; Sanchez-Soriano, N.; Prokop, A.

10.1101/385658 — cell biology — Posted on 2018-08-06

2137 A computational model of loss of dopaminergic cells in Parkinson’s disease due to glutamate-induced excitotoxicity

Muddapu, V. R.; Ramaswamy, S.; Chakravarthy, S. V.

10.1101/385138 — neuroscience — Posted on 2018-08-06

2138 Analysis and Prediction of Unplanned Intensive Care Unit Readmission using Recurrent Neural Networks with Long Short-Term Memory

Lin, Y.-W.; Zhou, Y.; Faghri, F.; Shaw, M. J.; Campbell, R. H.

10.1101/385518 — bioinformatics — Posted on 2018-08-06

2139 GranatumX: A community engaging and flexible software environment for single-cell analysis

Zhu, X.; Yunits, B.; Wolfgruber, T.; Poirion, O.; Arisdakessian, C.; Garmire, L.

10.1101/385591 — bioinformatics — Posted on 2018-08-06

2140 In vitro determination of the CB1 efficacy of illicit synthetic cannabinoids

Sachdev, S.; Vemuri, K.; Banister, S.; Longworth, M.; Kassiou, M.; Santiago, M. J.; Makriyannis, A.; Connor, M.

10.1101/385583 — pharmacology and toxicology — Posted on 2018-08-06

2141 Assessment of Functional Connectome Construction Strategies in Neurodegeneration

Vanhoecke, J.; McColgan, P.; Razi, A.; Gregory, S.; Seunarine, K.; Durr, A.; Roos, R.; Leavitt, B.; Scahill, R.; Clark, C.; Tabrizi, S.; Rees, G.; Track On-HD Investigators,

10.1101/385385 — neuroscience — Posted on 2018-08-06

2142 Evolutionary inference from QST-FST comparisons: disentangling local adaptation from altitudinal gradient selection in snapdragon plants

Marin, S.; Archambeau, J.; Bonhomme, V.; Lascoste, M.; Pujol, B.

10.1101/385377 — evolutionary biology — Posted on 2018-08-06

2143 pNeRF: Parallelized Conversion from Internal to Cartesian Coordinates

AlQuraishi, M.

10.1101/385450 — bioinformatics — Posted on 2018-08-06

2144 Deep-learning-based flexible pipeline for segmenting and tracking cells in 3D image time series for whole brain imaging

Wen, C.; Miura, T.; Fujie, Y.; Teramoto, T.; Ishihara, T.; Kimura, K. D.

10.1101/385567 — bioinformatics — Posted on 2018-08-06

2145 Mapping the human kinome in response to DNA damage

Owusu, M.; Bannauer, P.; Mourikis, A.; Jones, A.; Ferreira da Silva, J.; Caldera, M.; Wiedner, M.; Lardeau, C.-H.; Menche, J.; Kubicek, S.; Ciccarelli, F.; Loizou, J.

10.1101/385344 — systems biology — Posted on 2018-08-06

2146 A strain of an emerging Indian pathotype of Xanthomonas oryzae pv. oryzae defeats the rice bacterial blight resistance gene xa13 without inducing a clade III SWEET gene and is nearly identical to a recent Thai isolate

Carpenter, S.; Mishra, P.; Ghoshal, C.; Dash, P.; Wang, L.; Midha, S.; Laha, G. S.; Lore, J.; Kositratana, W.; Singh, N.; Singh, K.; Patil, P.; Oliva, R.; Patarapuwadol, S.; Bogdanove, A. J.; Rai, R.

10.1101/384289 — pathology — Posted on 2018-08-06

2147 Active information maintenance in working memory by a sensory cortex

Zhang, X.; Yan, W.; Wang, W.; Fan, H.; Hou, R.; Chen, Y.; Chen, Z.; Duan, S.; Compte, A.; Li, C.

10.1101/385393 — neuroscience — Posted on 2018-08-06

2148 Spatiotemporal analysis for detection of pre-symptomatic shape changes in neurodegenerative diseases: applied to GENFI study

Cury, C.; Durrleman, S.; Cash, D.; Lorenzi, M.; Nicholas, J.; Bocchetta, M.; van Swieten, J. C.; Borroni, B.; Galimberti, D.; Masellis, M.; Tartaglia, M.; Rowe, J. B.; Graff, C.; Tagliavini, F.; Frisoni, G. B.; Laforce, R.; Finger, E.; de Mendonca, A.; Sorbi, S.; Ourselin, S.; Rohrer, J. D.; Modat, M.; Genetic FTD Initiative,

10.1101/385427 — neuroscience — Posted on 2018-08-06

2149 A genetically encoded single-wavelength sensor for imaging cytosolic and cell surface ATP

Lobas, M.; Nagai, J.; Kronschlager, M. T.; Borden, P.; Marvin, J. S.; Looger, L. L.; Khakh, B. S.

10.1101/385484 — physiology — Posted on 2018-08-06

2150 Effects of cochlear synaptopathy on spontaneous and sound-evoked activity in the mouse inferior colliculus

Shaheen, L.; Liberman, M. C.

10.1101/381087 — neuroscience — Posted on 2018-08-06

2151 Just the Two of Us? A Family of Pseudomonas Megaplasmids Offers a Rare Glimpse Into the Evolution of Large Mobile Elements

Smith, B. A.; Leligdon, C.; Baltrus, D.

10.1101/385575 — microbiology — Posted on 2018-08-06

2152 Spatial autocorrelation: bane or bonus?

Pawley, M. D. M.; McArdle, B. H.

10.1101/385526 — ecology — Posted on 2018-08-06

2153 3D Tissue elongation via ECM stiffness-cued junctional remodeling

Chen, D.-Y.; Crest, J.; Streichan, S. J.; Bilder, D.

10.1101/384958 — developmental biology — Posted on 2018-08-06

2154 Qoala-T: A supervised-learning tool for quality control of FreeSurfer segmented MRI data

Klapwijk, E. T.; van de Kamp, F.; van der Meulen, M.; Peters, S.; Wierenga, L. M.

10.1101/278358 — neuroscience — Posted on 2018-08-06

2155 Etiology of fever in Ugandan children: identification of microbial pathogens using metagenomic next-generation sequencing and IDseq, a platform for unbiased metagenomic analysis

Ramesh, A.; Nakielny, S.; Hsu, J.; Kyohere, M.; Byaruhanga, O.; de Bourcy, C.; Egger, R.; Dimitrov, B.; Juan, Y.-F.; Sheu, J.; Wang, J.; Kalantar, K.; Langelier, C.; Ruel, T.; Mpimbaza, A.; Wilson, M. R.; Rosenthal, P. J.; DeRisi, J. L.

10.1101/385005 — genomics — Posted on 2018-08-06

2156 A combination of transcription factors mediates inducible interchromosomal pairing

Kim, S.; Dunham, M.; Shendure, J.

10.1101/385047 — genomics — Posted on 2018-08-05

2157 Circuit Degeneracy Facilitates Robustness and Flexibility of Navigation Behavior in C. elegans

Ikeda, M.; Nakano, S.; Giles, A. C.; Costa, W. S.; Gottschalk, A.; Mori, I.

10.1101/385468 — neuroscience — Posted on 2018-08-05

2158 Parameter tuning is a key part of dimensionality reduction via deep variational autoencoders for single cell RNA transcriptomics

Hu, Q.; Greene, C. S.

10.1101/385534 — bioinformatics — Posted on 2018-08-05

2159 Motor module generalization across balance and walking is reduced after stroke

Allen, J. L.; Kesar, T. M.; Ting, L. H.

10.1101/381939 — bioengineering — Posted on 2018-08-05

2160 Bile Acid Biosynthesis Avoiding Cholesterol

Griffiths, W. J.; Abdel-Khalik, J.; Crick, P. J.; Yutuc, E.; Ogundare, M.; Bigger, B. W.; Morris, A. A.; Shackleton, C. H.; Clayton, P. T.; Iida, T.; Sircar, R.; Marschall, H.-U.; Sjoval, J.; Bjorkhem, I.; Rohatgi, R.; Wang, Y.

10.1101/385419 — biochemistry — Posted on 2018-08-05

2161 Palantir characterizes cell fate continuities in human hematopoiesis

Setty, M.; Kiseliovas, V.; Levine, J.; Gayoso, A.; Mazutis, L.; Pe'er, D.

10.1101/385328 — systems biology — Posted on 2018-08-05

2162 Nitrogen utilisation by the metabolic generalist pathogen Mycobacterium tuberculosis

Agapova, A.; Hunt, D. M.; Petridis, M.; Garza-Garcia, A.; Sohaskey, C. D.; Carvalho, L. P.

10.1101/385278 — microbiology — Posted on 2018-08-05

2163 Why panmictic bacteria are rare

Yang, C.; Cui, Y.; Didelot, X.; Yang, R.; Falush, D.

10.1101/385336 — microbiology — Posted on 2018-08-05

2164 Pathogens, parasites, and parasitoids of ants: a synthesis of parasite biodiversity and epidemiological traits

Quevillon, L. E.; Hughes, D. P.

10.1101/384495 — ecology — Posted on 2018-08-05

2165 Monte-Carlo Diffusion-Enhanced Photon Inference: Distance Distributions and Conformational Dynamics in single-molecule FRET

Ingargiola, A.; Weiss, S.; Lerner, E.

10.1101/385252 — biophysics — Posted on 2018-08-05

2166 MEMS-Actuated Carbon Fiber Microelectrode for Neural Recording

Zoll, R. S.; Schindler, C. B.; Massey, T. L.; Drew, D. S.; Maharbiz, M. M.; Pister, K. S. J.

10.1101/385153 — bioengineering — Posted on 2018-08-05

2167 Test-retest reliability of functional brain network characteristics using resting-state EEG and graph theory

Moezzi, B.; Hordacre, B.; Berryman, C.; Ridding, M. C.; Goldsworthy, M. R.

10.1101/385302 — neuroscience — Posted on 2018-08-05

2168 Cortical Microcircuits from a Generative Vision Model

George, D.; Lavin, A.; Guntupalli, J. S.; Mely, D.; Hay, N.; Lazaro-Gredilla, M.

10.1101/379313 — neuroscience — Posted on 2018-08-05

2169 Bayesian Nonparametric Models Characterize Instantaneous Strategies in a Competitive Dynamic Game

McDonald, K.; Broderick, W. F.; Huettel, S.; Pearson, J.

10.1101/385195 — neuroscience — Posted on 2018-08-05

2170 An amplicon-based sequencing framework for accurately measuring intrahost virus diversity using PrimalSeq and iVar

Grubaugh, N. D.; Gangavarapu, K.; Quick, J.; Matteson, N. L.; Goes De Jesus, J.; Main, B. J.; Tan, A. L.; Paul, L. M.; Brackney, D. E.; Grewal, S.; Gurfield, N.; Van Rompay, K. K.; Isern, S.; Michael, S. F.; Coffey, L. L.; Loman, N. J.; Andersen, K. G.

10.1101/383513 — evolutionary biology — Posted on 2018-08-05

2171 Comparison of ecological, biological and anthropogenic causes of vehicle-wildlife collisions among three large herbivore species

Saint-Andrieux, C.; Calenge, C.; Bonenfant, C.

10.1101/385161 — ecology — Posted on 2018-08-05

2172 A cross-organism framework for supervised enhancer prediction with epigenetic pattern recognition and targeted validation

Sethi, A.; Gu, M.; Gumusgoz, E.; Chan, L.; Yan, K.-K.; Rozowsky, J. S.; Barozzi, I.; Afzal, V.; Akiyama, J.; Plajzer-Frick, I.; Yan, C.; Pickle, C.; Kato, M.; Garvin, T.; Pham, Q.; Harrington, A.; Mannion, B.; Lee, E.; Fukuda-Yuzawa, Y.; Visel, A.; Dickle, D. E.; Yip, K.; Sutton, R.; Pennacchio, L. A.; Gerstein, M.

10.1101/385237 — bioinformatics — Posted on 2018-08-05

2173 Dynamic self-organized error-correction of grid cells by border cells

Pollock, E.; Desai, N.; Wei, X.-X.; Balasubramanian, V.

10.1101/385229 — neuroscience — Posted on 2018-08-05

2174 The detection of hand tremor through the characteristics of finger movement while typing

Adams, W. R.

10.1101/385286 — neuroscience — Posted on 2018-08-05

2175 Pattern separation of spiketrains in hippocampal neurons

Madar, A. D.; Ewell, L. A.; Jones, M. V.

10.1101/107706 — neuroscience — Posted on 2018-08-05

2176 Effect of de novo transcriptome assembly on transcript quantification

Hsieh, P.-H.; Oyang, Y.-J.; Chen, C.-Y.

10.1101/380998 — bioinformatics — Posted on 2018-08-05

2177 A genetic, genomic, and computational resource for exploring neural circuit function

Davis, F. P.; Nern, A.; Picard, S.; Reiser, M. B.; Rubin, G. M.; Eddy, S. R.; Henry, G. L.

10.1101/385476 — neuroscience — Posted on 2018-08-05

2178 Conserved cell types with divergent features between human and mouse cortex

Hodge, R. D.; Bakken, T. E.; Miller, J. A.; Smith, K. A.; Barkan, E. R.; Graybuck, L. T.; Close, J. L.; Long, B.; Penn, O.; Yao, Z.; Eggermont, J.; Hollt, T.; Levi, B. P.; Shehata, S. I.; Aevermann, B.; Beller, A.; Bertagnolli, D.; Brouner, K.; Casper, T.; Cobbs, C.; Dalley, R.; Dee, N.; Ding, S.-L.; Ellenbogen, R. G.; Fong, O.; Garren, E.; Goldy, J.; Gwinn, R. P.; Hirschstein, D.; Keene, C. D.; Keshk, M.; Ko, A. L.; Lathia, K.; Mahfouz, A.; Maltzer, Z.; McGraw, M.; Nguyen, T. N.; Nyhus, J.; Ojemann, J. G.; Oldre, A.; Parry, S.; Reynolds, S.; Rimorin, C.; Shapovalova, N. V.; Somasundaram, S.;

10.1101/384826 — neuroscience — Posted on 2018-08-05

2179 Spatiotemporal ontogeny of brain wiring

Goulas, A.; Betzel, R. F.; Hilgetag, C. C.

10.1101/385369 — neuroscience — Posted on 2018-08-05

2180 Deciphering the roles of N-glycans on collagen-platelet interactions

Toonstra, C.; hu, Y.; Zhang, H.

10.1101/385179 — biochemistry — Posted on 2018-08-05

2181 On the molecular filters in cochlea transduction

Goussev, V.

10.1101/374363 — biophysics — Posted on 2018-08-05

2182 Image content is more important than Bouma’s Law for scene metamers

Wallis, T. S. A.; Funke, C. M.; Ecker, A. S.; Gatys, L. A.; Wichmann, F. A.; Bethge, M.

10.1101/378521 — neuroscience — Posted on 2018-08-05

2183 Genetic and phenotypic differentiation of lumpfish (Cyclopterus lumpus) across the North Atlantic: implications for conservation and aquaculture

Whittaker, B. A.; Consuegra, S.; Garcia de Leaniz, C.

10.1101/382119 — genetics — Posted on 2018-08-05

2184 Communication and quorum sensing in non-living mimics of eukaryotic cells

Niederholtmeyer, H.; Chaggan, C.; Devaraj, N. K.

10.1101/352666 — synthetic biology — Posted on 2018-08-05

2185 Uniform distribution of 35S promoter-driven mDII auxin control sensor in leaf primordia

Guan, C.; Du, F.; Jiao, Y.

10.1101/293753 — plant biology — Posted on 2018-08-05

2186 Bidirectional and context-dependent changes in theta and gamma oscillatory brain activity in noradrenergic cell-specific Hypocretin/Orexin receptor 1-KO mice

Li, S.; Franken, P.; Vassalli, A.

10.1101/123075 — neuroscience — Posted on 2018-08-05

2187 Dopamine neurons projecting to medial shell of the nucleus accumbens drive heroin reinforcement

Lüscher, C.; Corre, J.; Tian, L.; Patriarchi, T.; Loureïro, M.; Pascoli, V.; van Zessen, R.

10.1101/385039 — neuroscience — Posted on 2018-08-04

2188 Copy Number Variation In Gluthatione S-Transferase Variants Using Multiplex Ligation-Dependent Probe Amplification In A Health Population In Goiania - GO.

Silveira-Lacerda, E. d. P.; Pereira, L. C. G.; Gamba, B. F.; Bergamo, N. A.; Bicudo, L. A.; Arruda, J. T.

10.1101/384701 — molecular biology — Posted on 2018-08-04

2189 Pathway-specific asymmetries between ON and OFF visual signals

Ravi, S.; Ahn, D.; Greschner, M.; Chichilnisky, E. J.; Field, G. D.

10.1101/384891 — neuroscience — Posted on 2018-08-04

2190 Mating system of Ustilago esculenta and its polymorphism

Liang, S.; Huang, Y.-H.; Chiu, J.-Y.; Tseng, H.-W.; Haung, J.-H.; Shen, W.-C.

10.1101/384727 — microbiology — Posted on 2018-08-04

2191 Variability of collective dynamics in random tree networks of strongly-coupled stochastic excitable elements

Khaledi-Nasab, A.; Kromer, J.; Schimansky-Geier, L.; Neiman, A.

10.1101/382911 — biophysics — Posted on 2018-08-04

2192 Do We See Scale?

Linton, P.

10.1101/371948 — neuroscience — Posted on 2018-08-04

2193 Transcriptome analysis reveals negative correlation between transcripts of mitochondrial genes and L1HS, and positive correlation between KRAB-ZFPs and older LINE elements in normal somatic tissue

Chung, N.; Jonaid, G. M.; Quinton, S.; Ross, A.; Alberto, A.; Clymer, C.; Churchill, D.; Navarro Leija, O.; Han, M. V.

10.1101/385062 — genomics — Posted on 2018-08-04

2194 Increased H-Bond Stability Relates to Altered ε-Cleavage Efficiency and Aβ Levels in the I45T Familial Alzheimer’s Disease Mutant of APP

Götz, A.; Högel, P.; Silber, M.; Chaitoglou, I.; Luy, B.; Muhle-Goll, C.; Scharnagl, C.; Langosch, D.

10.1101/372698 — biophysics — Posted on 2018-08-04

2195 Overlaps in Brain Dynamical Functional Connectivity between Schizophrenia and Autism Spectrum Disorder

Andriamananjara, A.; Muntari, R.; Crimi, A.

10.1101/385146 — neuroscience — Posted on 2018-08-04

2196 Motor Learning Without Moving: Proprioceptive and Predictive Hand Localization After Passive Visuoproprioceptive Discrepancy Training

Mostafa, A. A.; 't Hart, B.; Henriques, D. Y.

10.1101/384941 — neuroscience — Posted on 2018-08-04

2197 Time-resolved mapping of genetic interactions to model rewiring of signaling pathways

Heigwer, F.; Scheeder, C.; Miersch, T.; Schmitt, B.; Blass, C.; Pour-Jamnani, M. V.; Boutros, M.

10.1101/384800 — genomics — Posted on 2018-08-04

2198 Glycosyltransferase homologs prevent promiscuous cell aggregation and promote multicellular development in the choanoflagellate S. rosetta

Wetzel, L.; Levin, T.; Hulett, R. E.; Chan, D.; King, G.; Aldayafleh, R.; Booth, D.; Sigg, M. A.; King, N.

10.1101/384453 — genetics — Posted on 2018-08-04

2199 In-Search Assignment of Monoisotopic Peaks Improves the Identification of Cross-Linked Peptides

Lenz, S.; Giese, S. H.; Fischer, L.; Rappsilber, J.

10.1101/335851 — bioinformatics — Posted on 2018-08-04

2200 Imagery of movements immediately following performance allows learning of motor skills that interfere

Sheahan, H. R.; Ingram, J. N.; Zalalyte, G. M.; Wolpert, D. M.

10.1101/299594 — animal behavior and cognition — Posted on 2018-08-04

2201 An automated, high-throughput image analysis pipeline enables genetic studies of shoot and root morphology in carrot (Daucus carota L.)

Turner, S. D.; Ellison, S. L.; Senalik, D. A.; Simon, P. W.; Spalding, E. P.; Miller, N. D.

10.1101/384974 — plant biology — Posted on 2018-08-04

2202 Brain peak width of skeletonised mean diffusivity (PSMD), processing speed, and other cognitive domains

Deary, I. J.; Ritchie, S. J.; Munoz Maniega, S.; Cox, S. R.; Valdes Hernandez, M. C.; Starr, J. M.; Wardlaw, J. M.; Bastin, M. E.

10.1101/385013 — neuroscience — Posted on 2018-08-04

2203 Etiology of fever in Ugandan children: identification of microbial pathogens using metagenomic next-generation sequencing and IDseq, a platform for unbiased metagenomic analysis

10.1101/385005 — genomics — Posted on 2018-08-04

2204 Effects of the maternal factor Zelda on zygotic enhancer activity in the Drosophila embryo

Li, X.-Y.; Eisen, M. B.

10.1101/385070 — developmental biology — Posted on 2018-08-04

2205 De Novo Mutational Signature Discovery in Tumor Genomes using SparseSignatures

Ramazzotti, D.; Lal, A.; Liu, K.; Tibshirani, R.; Sidow, A.

10.1101/384834 — bioinformatics — Posted on 2018-08-04

2206 Inference of genomic spatial organization from a whole genome bisulfite sequencing sample.

Raineri, E.; Serra, F.; Beekman, R.; Garcia Torre, B.; Vilarrasa-Blasi, R.; Martin-Subero, I.; Martl-Renom, M.; Gut, I.; Heath, S.

10.1101/384578 — bioinformatics — Posted on 2018-08-04

2207 Exogenous DCPTA ameliorates the soil drought effect on nitrogen metabolism in maize during the pre-female inflorescence emergence stage

Xie, T.; Gu, W.; Zhang, L.; Li, C.; Li, W.; Wei, S.

10.1101/385203 — physiology — Posted on 2018-08-04

2208 The Acinetobacter baumannii Mla system and glycerophospholipid transport to the outer membrane

Kamischke, C.; Fan, J.; Bergeron, J.; Kulasekara, H. D.; Dalebroux, Z. D.; Burrell, A.; Kollman, J. M.; Miller, S. I.

10.1101/384685 — microbiology — Posted on 2018-08-04

2209 Isolation and Characterization of a Myoviridae phage that lyses two Escherichia coli pathotypes

Cepko, L.; Garling, E.; Dinsdale, M.; Bandy, L.; Mellies, J.

10.1101/385104 — microbiology — Posted on 2018-08-04

2210 Mycobacteria-specific CD4+IFN-γ+ cell expresses naïve-surface markers and confers superior protection against tuberculosis infection compared to central and effector memory CD4+ T cell subsets

Chatterjee, S.; Yuan, J.; Tenant, J.; Pacatte, T.; Eickhoff, C.; Blazevic, A.

10.1101/384784 — immunology — Posted on 2018-08-04

2211 Signals of variation in human mutation rate at multiple levels of sequence context

Aikens, R. C.; Johnson, K. E.; Voight, B. F.

10.1101/385096 — genomics — Posted on 2018-08-04

2212 The Genomic Basis of Arthropod Diversity

Thomas, G. W. C.; Dohmen, E.; Hughes, D. S. T.; Murali, S. C.; Poelchau, M.; Glastad, K.; Anstead, C. A.; Ayoub, N. A.; Batterham, P.; Bellair, M.; Binford, G. J.; Chao, H.; Chen, Y. H.; Childers, C.; Dinh, H.; Doddapaneni, H.; Duan, J. J.; Dugan, S.; Esposito, L. A.; Friedrich, M.; Garb, J.; Gasser, R. B. B.; Goodisman, M. A. D.; Gundersen-Rindal, D. E.; Han, Y.; Handler, A. M.; Hatakeyama, M.; Hering, L.; Hunter, W. B.; Ioannidis, P.; Jayaseelan, J. C.; Kalra, D.; Khila, A.; Korhonen, P. K.; Lee, C. E.; Lee, S. L.; Li, Y.; Lindsey, A. R. I.; Mayer, G.; McGregor, A. P.; McKenna, D. D.; Misof,

10.1101/382945 — genomics — Posted on 2018-08-04

2213 Pervasive Transcription Fine-tunes Replication Origin Activity

Candelli, T.; Gros, J.; Libri, D.

10.1101/384859 — genetics — Posted on 2018-08-04

2214 Exploring Various Polygenic Risk Scores for Basal Cell Carcinoma, Cutaneous Squamous Cell Carcinoma and Melanoma in the Phenomes of the Michigan Genomics Initiative and the UK Biobank

Fritsche, L. G.; Beesley, L. J.; VandeHaar, P.; Peng, R. B.; Salvatore, M.; Zawistowski, M.; Gagliano, S.; Das, S.; LeFaive, J.; Kaleba, E. O.; Klumpner, T. T.; Moser, S. E.; Blanc, V.; Brummett, C.; Kheterpal, S.; Abecasis, G.; Gruber, S. B.; Mukherjee, B.

10.1101/384909 — genetics — Posted on 2018-08-04

2215 Condensin controls mitotic chromosome stiffness and stability without forming a structurally contiguous scaffold

Marko, J.; Biggs, R.; Sun, M.; Hornick, J.

10.1101/384982 — cell biology — Posted on 2018-08-04

2216 Annexin A1 drives macrophage skewing towards a resolving phenotype to accelerate the regeneration of muscle injury through AMPK activation

McArthur, S.; Gobbetti, T.; Juban, G.; Desgeorges, T.; Theret, M.; Gondin, J.; Toller-Kawahisa, J.; Reutelingsperger, C.; Perretti, M.; Mounier, R.

10.1101/375709 — cell biology — Posted on 2018-08-04

2217 Hessian single molecule localization microscopy using sCMOS camera

Xue, F.; He, W.; Xu, F.; Zhang, M.; Chen, L.; Xu, P.

10.1101/385112 — biophysics — Posted on 2018-08-04

2218 Towards comprehensive allosteric control over protein activity

Guarnera, E.; Berezovsky, I. N.

10.1101/384198 — biophysics — Posted on 2018-08-04

2219 The necessary component of regulatory interactions: identification and characterization of putative regulatory motifs. Case study on the control of seminal fluid proteins through regulatory hubs in D. melanogaster

Mohorianu, I.

10.1101/379610 — bioinformatics — Posted on 2018-08-04

2220 Nuisance Effects and the Limitations of Nuisance Regression in Dynamic Functional Connectivity fMRI

Nalci, A.; Rao, B. D.; Liu, T. T.

10.1101/285239 — neuroscience — Posted on 2018-08-03

Huckins, J.; Adeyemo, B.; Miezin, F. M.; Power, J. D.; Gordon, E. M.; Laumann, T. O.; Heatherton, T. F.; Petersen, S. E.; Kelley, W. M.

10.1101/304865 — neuroscience — Posted on 2018-08-03

2222 IPSE, a urogenital parasite-derived immunomodulatory protein, ameliorates ifosfamide-induced hemorrhagic cystitis through downregulation of pro-inflammatory pathways

Mbanefo, E.; Le, L.; Zee, R.; Banskota, N.; Ishida, K.; Pennington, L.; Odegaard, J.; Jardetzky, T.; Alouffi, A.; Falcone, F.; Hsieh, M.

10.1101/381764 — immunology — Posted on 2018-08-03

2223 An efficient timer and sizer of protein motions reveals the time scales of functional dynamics in the ribosome

Chan, J.; Lin, H.-R.; Takemura, K.; Chang, K.-C.; Chang, Y.-Y.; Joti, Y.; Kitao, A.; Yang, L.-W.

10.1101/384511 — biophysics — Posted on 2018-08-03

2224 Cancer cell lipid class homeostasis is altered under nutrient-deprivation but stable under hypoxia

Lisec, J.; Jaeger, C.; Zaidi, N.

10.1101/382457 — biochemistry — Posted on 2018-08-03

2225 The limiting DNA replication initiation factors Sld2 and Sld3 influence origin efficiency independent of origin firing time

Lynch, K. L.; Kwan, E. X.; Alvino, G. M.; Brewer, B. J.; Raghuraman, M. K.

10.1101/384644 — molecular biology — Posted on 2018-08-03

2226 Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function

Shifrut, E.; Carnevale, J.; Tobin, V.; Roth, T. L.; Woo, J. M.; Bui, C.; Li, P. J.; Diolaiti, M.; Ashworth, A.; Marson, A.

10.1101/384776 — immunology — Posted on 2018-08-03

2227 Sfp1 regulates the SAGA component Tra1 in response to proteotoxic stress in Saccharomyces cerevisiae

Jiang, Y.; Genereaux, J.; Berg, M. D.; Ahmed, K.; Duennwald, M.; Brandl, C. J.; Lajoie, P.

10.1101/384602 — genetics — Posted on 2018-08-03

2228 Molecular recording of mammalian embryogenesis

Chan, M.; Smith, Z. D.; Grosswendt, S.; Kretzmer, H.; Norman, T.; Adamson, B.; Jost, M.; Quinn, J. J.; Yang, D.; Meissner, A.; Weissman, J. S.

10.1101/384925 — developmental biology — Posted on 2018-08-03

2229 A Bayesian approach to beam-induced motion correction in cryo-EM single-particle analysis

Zivanov, J.; Nakane, T.; Scheres, S.

10.1101/384537 — biophysics — Posted on 2018-08-03

2230 bayNorm: Bayesian gene expression recovery, imputation and normalisation for single cell RNA-sequencing data

Tang, W.; Bertaux, F.; Thomas, P.; Stefanelli, C.; Saint, M.; Marguerat, S. B.; Shahrezaei, V.

10.1101/384586 — bioinformatics — Posted on 2018-08-03

2231 Corrigendum to: T cell apoptosis at the maternal-fetal interface in early human pregnancy, involvement of galectin-1.- A correction with an important twist.

Kopcow, H.

10.1101/374322 — immunology — Posted on 2018-08-03

2232 A Transcriptome Wide Association Study implicates specific pre- and post-synaptic abnormalities in Schizophrenia

Hall, L. S.; Medway, C. W.; Pardinas, A. F.; Rees, E. G.; Escott-Price, V.; Pocklington, A.; Holmans, P. A.; Walters, J. T.; Owen, M. J.; ODonovan, M. C.

10.1101/384560 — genetics — Posted on 2018-08-03

2233 RNA-seq reveals few differences in resistant and susceptible responses of barley to infection by the spot blotch pathogen Bipolaris sorokiniana

Haas, M.; Mascher, M.; Castell-Miller, C.; Steffenson, B. J.

10.1101/384529 — genetics — Posted on 2018-08-03

2234 Insight into the genetic architecture of back pain and its risk factors from a study of 509,000 individuals

Freidin, M. B.; Tsepilov, Y. A.; Palmer, M.; Karssen, L. C.; CHARGE Musculoskeletal Working Group, ; Suri, P.; Aulchenko, Y. S.; Williams, F. M.

10.1101/384255 — genetics — Posted on 2018-08-03

2235 Novel allosteric mechanism of p53 activation by small molecules for targeted anticancer therapy

10.1101/384248 — cancer biology — Posted on 2018-08-03

2236 Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine-resistance in breast cancer

Morotti, M.; Bridges, E.; Valli, A.; Choudhry, H.; Sheldon, H.; Wigfield, S.; Gray, N.; Jones, D.; Teoh, E. J.; Cheng, W.-C.; Lord, S.; Haider, S.; Mcintyre, A.; Goberdhan, D. C. I.; Buffa, F.; Harris, A. L.

10.1101/384628 — cancer biology — Posted on 2018-08-03

2237 Genome analysis of the unicellular eukaryote Euplotes vannus reveals molecular basis for sex determination and tolerance to environmental stresses

Chen, X.; Jiang, Y.; Gao, F.; Zheng, W.; Krock, T. J.; Stover, N. A.; Lu, C.; Katz, L. A.; Song, W.

10.1101/357715 — genomics — Posted on 2018-08-03

2238 Clownfishes are a genetic model of exceptional longevity and reveal molecular convergence in the evolution of lifespan

Sahm, A.; Almaida-Pagan, P.; Bens, M.; Mutalipassi, M.; Lucas-Sanchez, A.; de Costa Ruiz, J.; Goerlach, M.; Cellerino, A.

10.1101/380709 — evolutionary biology — Posted on 2018-08-03

2239 Whole-genome deep learning analysis reveals causal role of noncoding mutations in autism

Zhou, J.; Park, C.; Theesfeld, C.; Yuan, Y.; Sawicka, K.; Darnell, J.; Scheckel, C.; Fak, J.; Tajima, Y.; Darnell, R.; Troyanskaya, O.

10.1101/319681 — genomics — Posted on 2018-08-03

2240 A low-threshold potassium current enhances sparseness and reliability in a model of avian auditory cortex

Bjoring, M.; Meliza, C. D.

10.1101/249011 — neuroscience — Posted on 2018-08-03

2241 Interferon-alpha2 but not interferon-gamma serum levels are associated with intramuscular fat in obese patients with nonalcoholic fatty liver disease

Tarantino, G.; Costantini, S.; Citro, V.; Conforti, P.; Capone, F.; Sorice, A.; Capone, D.

10.1101/384297 — epidemiology — Posted on 2018-08-03

2242 Exocyst Dynamics During Vesicle Tethering and Fusion

Ahmed, S. M.; Nishida-Fukuda, H.; Li, Y.; McDonald, W. H.; Gradinaru, C.; Macara, I. G.

10.1101/354449 — cell biology — Posted on 2018-08-03

2243 A Ca2+-regulated deAMPylation switch in bacterial and human FIC proteins.

Veyron, S.; Oliva, G.; Rolando, M.; Buchrieser, C.; Peyroche, G.; Cherfils, J.

10.1101/323253 — biochemistry — Posted on 2018-08-03

2244 Ending AIDS: trends in the incidence of HIV in eastern and southern Africa

Williams, B. G.; Granich, R.

10.1101/383372 — epidemiology — Posted on 2018-08-03

2245 Disentangling the contribution of childhood and adulthood circumstances and genetics to phenotypic aging: prospective cohort study

Liu, Z.; Chen, X.; Gill, T. M.; Ma, C.; Crimmins, E. M.; Levine, M. E.

10.1101/384040 — epidemiology — Posted on 2018-08-03

2246 A novel interplay between GEFs orchestrates Cdc42 activation in cell polarity and cytokinesis

Hercyk, B.; Rich, J.; Das, M. E.

10.1101/364786 — cell biology — Posted on 2018-08-03

2247 Multi-omic tumor data reveal diversity of molecular mechanisms that correlate with survival

Ramazzotti, D.; Lal, A.; Wang, B.; Batzoglou, S.; Sidow, A.

10.1101/267245 — cancer biology — Posted on 2018-08-03

2248 Predicting Response to Platin Chemotherapy Agents with Biochemically-inspired Machine Learning

Mucaki, E. J.; Zhao, J. Z. L.; Lizotte, D.; Rogan, P. K.

10.1101/231712 — pharmacology and toxicology — Posted on 2018-08-03

2249 Kinetic Pathways of Topology Simplification by Type-II Topoisomerases in Knotted Supercoiled DNA

Ziraldo, R.; Hanke, A.; Levene, S. D.

10.1101/383901 — molecular biology — Posted on 2018-08-03

2250 The genetics of the mood disorder spectrum: genome-wide association analyses of over 185,000 cases and 439,000 controls

Coleman, J.; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, ; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, ; Breen, G.

10.1101/383331 — genomics — Posted on 2018-08-03

2251 Population size history from short genomic scaffolds: how short is too short?

Gower, G.; Tuke, S.; Rohrlach, A. B.; Soubrier, J.; Llamas, B.; Bean, N.; Cooper, A.

10.1101/382036 — genetics — Posted on 2018-08-03

2252 MoB (Measurement of Biodiversity): a method to separate the scale-dependent effects of species abundance distribution, density, and aggregation on diversity change

McGlinn, D. J.; Xiao, X.; May, F.; Gotelli, N. J.; Engel, T.; Blowes, S.; Knight, T.; Purschke, O.; Chase, J.; McGill, B.

10.1101/244103 — ecology — Posted on 2018-08-03

2253 Energy expenditure and body composition changes after an isocaloric ketogenic diet in overweight and obese men: a secondary analysis of energy expenditure and physical activity

Friedman, M. I.; Appel, S.

10.1101/383752 — physiology — Posted on 2018-08-03

2254 Two spatially distinct posterior alpha sources fulfill different functional roles in attention

Sokoliuk, R.; Mayhew, S. D.; Aquino, K.; Wilson, R.; Brookes, M. J.; Francis, S. T.; Hanslmayr, S.; Mullinger, K. J.

10.1101/384065 — neuroscience — Posted on 2018-08-03

2255 Complex dynamics in simplified neuronal models: reproducing Golgi cell electroresponsiveness

Geminiani, A.; Casellato, C.; Locatelli, F.; Prestori, F.; Pedrocchi, A.; D'Angelo, E.

10.1101/378315 — neuroscience — Posted on 2018-08-03

2256 Physicochemical amino acid properties better describe substitution rates in large populations

Weber, C. C.; Whelan, S.

10.1101/378893 — evolutionary biology — Posted on 2018-08-03

2257 Transcriptomic and functional analysis of the oosome, a unique form of germplasm in the wasp Nasonia vitripennis

Lynch, J. A.; Quan, H.

10.1101/384032 — developmental biology — Posted on 2018-08-03

2258 Trends and perspectives on the use of social network analysis in behavioural ecology: a bibliometric approach

Webber, Q. M. R.; Vander Wal, E.

10.1101/379008 — animal behavior and cognition — Posted on 2018-08-03

2259 Single-nucleus RNA sequencing shows convergent evidence from different cell types for altered synaptic plasticity in major depressive disorder.

Nagy, C.; Maitra, M.; Suderman, M.; Theroux, J.-F.; Mechawar, N.; Ragoussis, J.; Turecki, G.

10.1101/384479 — neuroscience — Posted on 2018-08-03

2260 Unique morphogenetic signatures define mammalian neck muscles and associated connective tissues

Heude, E.; Tesarova, M.; Sefton, E. M.; Jullian, E.; Adachi, N.; Grimaldi, A.; Zikmund, T.; Kaiser, J.; Kardon, G.; Kelly, R.; Tajbakhsh, S.

10.1101/380774 — developmental biology — Posted on 2018-08-03

2261 Processing of eukaryotic Okazaki fragments by redundant nucleases can be uncoupled from ongoing DNA replication in vivo

Kahli, M.; Osmundson, J. S.; Yeung, R.; Smith, D. J.

10.1101/384503 — molecular biology — Posted on 2018-08-03

2262 HERI-1 is a Chromodomain Protein that Negatively Regulates Transgenerational Epigenetic Inheritance

Perales, R.; Pagano, D.; Wan, G.; Fields, B.; Saltzman, A. L.; Kennedy, S.

10.1101/384792 — genetics — Posted on 2018-08-03

2263 Using the Wax moth larva Galleria mellonella infection model to detect emerging bacterial pathogens

Hernandez, R.; Hesse, E.; Dowling, A.; Coyle, N.; Feil, E.; Gaze, W.; Vos, M.

10.1101/327015 — microbiology — Posted on 2018-08-03

2264 Cost-effectiveness of telephone-based weight loss support for patients with knee osteoarthritis: Results of an economic evaluation alongside a pragmatic randomised controlled trial

O'Brien, K. M.; van Dongen, J. M.; Williams, A.; Kamper, S. J.; Wiggers, J.; Hodder, R. K.; Campbell, E.; Robson, E. K.; Haskins, R.; Rissel, C.; Williams, C. M.

10.1101/284588 — clinical trials — Posted on 2018-08-03

2265 Deep Bidirectional Recurrent Neural Networks as End-To-End Models for Smoking Status Extraction from Clinical Notes in Spanish

Esteban, S.; Rodriguez Tablado, M.; Peper, F. E.; Terrasa, S. A.; Kopitowski, K. S.

10.1101/320846 — bioinformatics — Posted on 2018-08-03

2266 3D grid codes in human entorhinal cortex: Theoretical and methodological considerations and fMRI findings

Kim, M.; Maguire, E. A.

10.1101/282327 — neuroscience — Posted on 2018-08-03

2267 Selection for pollen competitive ability in mixed mating systems

Peters, M. A. E.; Weis, A. E.

10.1101/222117 — evolutionary biology — Posted on 2018-08-03

2268 Dissection of ligand-CDK8/CycC unbinding free energy barriers and kinetics by molecular simulations

Tang, Z.; Chang, C.-e. A.

10.1101/169607 — biophysics — Posted on 2018-08-03

2269 Fronto-central P3a to distracting sounds: an index of their arousing properties

Masson, R.; Bidet-Caulet, A.

10.1101/333419 — neuroscience — Posted on 2018-08-03

2270 Repeated evolution of asexuality involves convergent gene expression changes

Parker, D. J.; Bast, J.; Jalvingh, K.; Dumas, Z.; Robinson-Rechavi, M.; Schwander, T.

10.1101/364869 — evolutionary biology — Posted on 2018-08-03

2271 Leveraging pathogen community distributions to understand outbreak and emergence potential

Dallas, T. A.; Carlson, C. J.; Poisot, T.

10.1101/336065 — epidemiology — Posted on 2018-08-03

2272 Powerful and Efficient Strategies for Genetic Association Testing of Symptom and Questionnaire Data in Psychiatric Genetic Studies

Holleman, A. M.; Broadaway, K. A.; Duncan, R.; Almli, L. M.; Bradley, B.; Ressler, K. J.; Ghosh, D.; Mulle, J. G.; Epstein, M. P.

10.1101/383471 — genetics — Posted on 2018-08-03

2273 Haplotype-phased Callithrix jacchus embryonic stem cell line for genome editing using CRISPR/Cas9

Zhou, B.; Ho, S. S.; Leung, L. C.; Ward, T. R.; Ho, M.; Plastini, M. J.; Vermilyea, S. C.; Emborg, M. E.; Golos, T. G.; Mourrain, P.; Perrin, D.; Parker, K. J.; Urban, A. E.

10.1101/373886 — genetics — Posted on 2018-08-03

2274 Inducing controlled cell cycle arrest and re-entry during asexual proliferation of Plasmodium falciparum malaria parasites.

Van Biljon, R. A.; Niemand, J.; van Wyk, R. D.; Clark, K.; Brider, B.; Abrie, C.; Von Gruning, H.; Smidt, W.; Smit, A.; Reader, J.; Painter, H.; Llinas, M.; Doerig, C.; Birkholtz, L.-M.

10.1101/368431 — cell biology — Posted on 2018-08-03

2275 The molecular signatures of compatible and incompatible pollination

Kodera, C.; Just, J.; Da Rocha, M.; Larrieu, A.; Riglet, L.; Legrand, J.; Rozier, F.; Gaude, T.; Fobis-Loisy, I.

10.1101/374843 — plant biology — Posted on 2018-08-03

2276 A different state of mind: neural activity related to volitionally up- versus downregulating cortical excitability

Ruddy, K. L.; Balsters, J.; Mantini, D.; Liu, Q.; Kassraian-Fard, P.; Enz, N.; Mihelj, E.; Subhash Chander, B.; Soekadar, S. R.; Wenderoth, N.

10.1101/370130 — neuroscience — Posted on 2018-08-03

2277 Normative age modelling of cortical thickness in autistic males

Bethlehem, R. A. I.; Seidlitz, J.; Romero-Garcia, R.; Dumas, G.; Lombardo, M. V.

10.1101/252593 — neuroscience — Posted on 2018-08-03

2278 Macrophage-induced rifampin tolerance across Mycobacterium tuberculosis lineages is Rv1258c-dependent

Adams, K. N.; Verma, A. K.; Gopalaswamy, R.; Adikesavalu, H.; Singhal, D. K.; Tripathy, S.; Ranganathan, U. D. R.; Sherman, D. R.; Urdahl, K. B.; Ramakrishnan, L.; Hernandez, R. E.

10.1101/383109 — microbiology — Posted on 2018-08-03

2279 Host cell metabolism contributes to delayed-death kinetics of apicoplast inhibitors in Toxoplasma gondii

Amberg-Johnson, K.; Yeh, E.

10.1101/384123 — microbiology — Posted on 2018-08-03

2280 Understanding and predicting extreme wildfires in the contiguous United States

Joseph, M. B.; Rossi, M. W.; Mietkiewicz, N. P.; Mahood, A. L.; Cattau, M. E.; St. Denis, L. A.; Nagy, R. C.; Iglesias, V.; Abatzoglou, J. T.; Balch, J. K.

10.1101/384115 — ecology — Posted on 2018-08-03

2281 Changes in structural network topology correlate with severity of hallucinatory behaviour in Parkinson’s disease

Hall, J. M.; O'Callaghan, C.; Muller, A. J.; Ehgoetz Martens, K. A.; Philips, J. R.; Moustafa, A. A.; Lewis, S. J.; Shine, J. M.

10.1101/383141 — neuroscience — Posted on 2018-08-03

2282 Deep learning image recognition enables efficient genome editing in zebrafish by automated injections

Cordero-Maldonado, M. L.; Perathoner, S.; van der Kolk, K.-J.; Boland, R.; Heins-Marroquin, U.; Spaink, H. P.; Meijer, A. H.; Crawford, A. D.; de Sonneville, J.

10.1101/384735 — molecular biology — Posted on 2018-08-03

2283 Resolving the complex Bordetella pertussis genome using barcoded nanopore sequencing

Ring, N.; Abrahams, J.; Jain, M.; Olsen, H.; Preston, A.; Bagby, S.

10.1101/381640 — microbiology — Posted on 2018-08-03

2284 Improving the diagnostic yield of exome-sequencing, by predicting gene-phenotype associations using large-scale gene expression analysis

Deelen, P.; van Dam, S.; Herkert, J. C.; Karjalainen, J. M.; Brugge, H.; Abbott, K. M.; van Diemen, C. C.; van der Zwaag, P. A.; Gerkes, E. H.; Folkertsma, P.; Gillett, T.; van der Velde, K. J.; Kanninga, R.; van den Akker, P.; Jan, S. Z.; Hoorntje, E. T.; te Rijdt, W. P.; Vos, Y. J.; Jongbloed, J. D. H.; van Ravenswaaij-Arts, C. M. A.; Sinke, R.; Sikkema-Raddatz, B.; Kerstjens-Frederikse, W. S.; Swertz, M. A.; Franke, L.

10.1101/375766 — genetics — Posted on 2018-08-03

2285 Long-read amplicon denoising

Kumar, V.; Vollbrecht, T.; Chernyshev, M.; Mohan, S.; Hanst, B.; Bavafa, N.; Lorenzo, A.; Ketteringham, R.; Eren, K.; Golden, M.; Oliveira, M. F.; Murrell, B.

10.1101/383794 — bioinformatics — Posted on 2018-08-03

2286 Increasing consensus of context-specific metabolic models by integrating data-inferred cell functions

Richelle, A.; Chiang, A. W. T.; Kuo, C.-C.; Lewis, N. E.

10.1101/384099 — systems biology — Posted on 2018-08-03

2287 Characterization of cis-prenyltransferase complexes in guayule (Parthenium argentatum), an alternative natural rubber-producing plant

Lakusta, A. M.; Kwon, M.; Kwon, E.-J. G.; Stonebloom, S.; Scheller, H. V.; Ro, D.-K.

10.1101/384149 — plant biology — Posted on 2018-08-03

2288 Reconciling age-related changes in behavioural and neural indices of human perceptual decision making

McGovern, D. P.; Hayes, A.; Kelly, S. P.; O'Connell, R.

10.1101/228965 — neuroscience — Posted on 2018-08-03

2289 Performing Reflexive Toxin A/B Enzyme Immunoassay in a Two-Step Algorithm for the Diagnosis of Clostridium difficile Infection Has Limited Clinical Utility

Mounajjed, M. M.; Pease, R.; Jung-Hynes, B.; Safdar, N.; Chen, D. J.

10.1101/384214 — microbiology — Posted on 2018-08-03

2290 Engrafted parenchymal brain macrophages differ from host microglia in transcriptome, epigenome and response to challenge

Shemer, A.; Grozovski, J.; Leng Tay, T.; Tao, J.; Volaski, A.; Suess, P.; Ardura-Fabregat, A.; Gross, M.; Kim, J.-S.; David, E.; Chappell-Maor, L.; Thielecke, L.; Glass, C. K.; Cornils, K.; Prinz, M.; Jung, S.

10.1101/369942 — immunology — Posted on 2018-08-03

2291 Chromosome-scale assemblies reveal the structural evolution of African cichlid genomes

Conte, M. A.; Joshi, R.; Moore, E. C.; Nandamuri, S. P.; Gammerdinger, W. J.; Roberts, R. B.; Carleton, K. L.; Lien, S.; Kocher, T. D.

10.1101/383992 — genomics — Posted on 2018-08-03

2292 Evolutionary proteomics reveals distinct patterns of complexity and divergence between lepidopteran sperm morphs

Whittington, E.; Karr, T.; Mongue, A. J.; Dorus, S.; Walters, J.

10.1101/384164 — evolutionary biology — Posted on 2018-08-03

2293 Orthogonal linear separation analysis: an approach to decompose the complex effect of a perturbagen

Mizuno, T.; Kinoshita, S.; Maedera, S.; Ito, T.; Kusuhara, H.

10.1101/384446 — bioinformatics — Posted on 2018-08-03

2294 Focus of attention modulates the heartbeat evoked potential

Petzschner, F. H.; Weber, L. A.; Wellstein, K. V.; Paolini, G.; Tri Do, C.; Stephan, K. E.

10.1101/384305 — neuroscience — Posted on 2018-08-03

2295 Individuals with ventromedial frontal damage have more unstable but still fundamentally transitive preferences

Yu, L. Q.; Dana, J.; Kable, J. W.

10.1101/384024 — neuroscience — Posted on 2018-08-03

2296 The small and large ribosomal subunits depend on each other for stability and accumulation

Lindahl, L.; Gregory, B.; Rahman, N.; Bommakanti, A.; Shamsuzzaman, M.; Thapa, M.; Lescure, A.; Zengel, J.

10.1101/384362 — molecular biology — Posted on 2018-08-03

2297 Developing a newborn rat model of meningitis without concomitant bacteremia by intraventricular injection of K1 (-) Escherichia coli

Park, W. S.; AHN, S. Y.; Chang, Y. S.; Sung, D. K.; Kim, Y. E.; Sung, S. I.; JOO, S. Y.

10.1101/384750 — microbiology — Posted on 2018-08-03

2298 Standardized biogeographic grouping system for annotating populations in pharmacogenetic research

Huddart, R.; Fohner, A. E.; Whirl-Carrillo, M.; Wojcik, G. L.; Gignoux, C. R.; Popejoy, A. B.; Bustamante, C. D.; Altman, R. B.; Klein, T.

10.1101/384016 — genetics — Posted on 2018-08-03

2299 A New Phylogenetic Framework for the Animal-adapted Mycobacterium tuberculosis Complex

Brites, D.; Loiseau, C.; Menardo, F.; Borrell, S.; Boniotti, M. B.; Warren, R.; Dippenaar, A.; Parsons, S. D. C.; Beisel, C.; Behr, M. A.; Fyfe, J. A.; Coscolla, M.; Gagneux, S.

10.1101/384263 — evolutionary biology — Posted on 2018-08-03

2300 Multilayer network analysis of miRNA and protein expression profiles in breast cancer patients

Zhang, Y.; Chen, J.; Wang, D.; Cong, W.; Lai, B. S.; Yi, Z.

10.1101/384768 — bioinformatics — Posted on 2018-08-03

2301 Biodynamics: A novel quasi-first principles theory on the fundamental mechanisms of cellular function/dysfunction and the pharmacological modulation thereof

Selvaggio, G.; Pearlstein, R. A.

10.1101/384719 — systems biology — Posted on 2018-08-03

2302 Potential Application of Bacteriophages in Enrichment Culture for Improved Prenatal Streptococcus agalactiae Screening

Uchiyama, J.; Matsui, H.; Murakami, H.; Kato, S.-i.; Watanabe, N.; Nasukawa, T.; Mizukami, K.; Ogata, M.; Sakaguchi, M.; Matsuzaki, S.; Hanaki, H.

10.1101/384222 — microbiology — Posted on 2018-08-03

2303 Non-coding Class Switch Recombination-related transcription in human normal and pathological immune responses

Kuri-Magana, H.; Collado-Torres, L.; Jaffe, A. E.; Valdovinos-Torres, H.; Ovilla-Munoz, M.; Tellez-Sosa, J. M.; Bonifaz-Alfonzo, L. C.; Martinez-Barnetche, J.

10.1101/384172 — immunology — Posted on 2018-08-03

2304 GenoDup Pipeline: a tool to detect genome duplication using the dS-based method

Mao, Y.; Satoh, N.

10.1101/384388 — bioinformatics — Posted on 2018-08-03

2305 A pilot investigation of chemonucleolysis-induced intervertebral disc degeneration in the ovine lumbar spine

Borem, R.; Walters, J.; Madeline, A.; Madeline, L.; Easley, J.; Gill, S.; Mercuri, J.

10.1101/384743 — bioengineering — Posted on 2018-08-03

2306 Direct Crystal Formation from Micronized Bone and Lactic Acid: The Writing on the Wall for Calcium-Containing Crystal Pathogenesis in Osteoarthritis?\"

Bulysheva, A. A.; Sori, N.; Francis, M. P.

10.1101/384669 — pathology — Posted on 2018-08-03

2307 A revisit to a low-cost method for the isolation of microsatellite markers: the case of the endangered Malayan tapir (Tapirus indicus)

Lim, Q. L.; Ismail, A.; Arumugam, R.; Ng, W. L.; Yong, C. S. Y.; Ismail, A.; Rovie-Ryan, J. J.; Rosli, N.; Annavi, G.

10.1101/384651 — genetics — Posted on 2018-08-03

2308 Genome-wide identification and functional analysis of circRNAs in Zea mays

Li, G.; Tang, B.; Hao, Z.; Zhu, Y.; Zhang, H.

10.1101/384693 — genetics — Posted on 2018-08-03

2309 Comparative analysis of the effect of genomic isolators flanking transgenes to avoid positional effects in Arabidopsis

Perez-Gonzalez, A.; Caro, E.

10.1101/384487 — synthetic biology — Posted on 2018-08-03

2310 Fine-mapping cis-regulatory variants in diverse human populations

Tehranchi, A.; Hie, B.; Dacre, M.; Kaplow, I.; Pettie, K.; Combs, P.; Fraser, H. B.

10.1101/384396 — molecular biology — Posted on 2018-08-03

2311 A Cell Proliferation and Inflammatory Signature is Induced by Lawsonia intracellularis Infection in Swine

Isaacson, R. E.; Leite, F. L.; Abrahante, J. E.; Vasquez, E.; Vannucci, F. A.; Gebhart, C. J.; Winkelman, N.; Mueller, A.; Torrison, J.; Rambo, Z.

10.1101/384230 — microbiology — Posted on 2018-08-03

2312 Single-cell RNA-seq reveals dynamic transcriptome profiling in human early neural differentiation

Shang, Z.; Chen, D.; Wang, Q.; Wang, S.; Deng, Q.; Wu, L.; Liu, C.; Ding, X.; Wang, S.; Zhong, J.; Zhang, D.; Cai, X.; Zhu, S.; Yang, H.; Liu, L.; Fink, J. L.; Chen, F.; Liu, X.; Gao, Z.; Xu, X.

10.1101/384131 — developmental biology — Posted on 2018-08-03

2313 Spermatoproteasome-deficient mice are proficient in meiotic DNA repair but defective in meiotic exit

Gomez-H, L.; Felipe-Medina, N.; Codezo, Y. B.; Garcia-Valiente, R.; Ramos, I.; Roig, I.; Sanchez-Martin, M.; de Rooij, D. G.; Llano, E.; Pendas, A. M.

10.1101/384354 — cell biology — Posted on 2018-08-03

2314 KATANIN-dependent mechanical properties of the stigmatic cell wall regulate pollen tube pathfinding

Riglet, L.; Rozier, F.; Kodera, C.; Fobis-Loisy, I.; Gaude, T.

10.1101/384321 — plant biology — Posted on 2018-08-03

2315 Variability of collective dynamics in random tree networks of strongly-coupled stochastic excitable elements

Khaledi-Nasab, A. K.-N.; Kromer, J.; Schimansky-Geier, L.; Neiman, A.

10.1101/382911 — biophysics — Posted on 2018-08-03

2316 Mathematical modeling supports fate restriction in neurogenic progenitors of the embryonic ventral spinal cord

Azaïs, M.; Agius, E.; Blanco, S.; Gautrais, J.; Molina, A.; Pituello, F.; Tregan, J.-M.

10.1101/384347 — developmental biology — Posted on 2018-08-03

2317 Structural capture of an intermediate transport state of a CLC Cl-/H+ antiporter

Lim, H.-H.; Park, K.

10.1101/384404 — biochemistry — Posted on 2018-08-03

2318 Lipid associated polygenic enrichment in Alzheimer’s disease

Broce, I.; Tan, C. H.; Fan, C. C.; Witoelar, A.; Wen, N.; Jansen, I.; Hess, C.; Dillon, W.; Glastonbury, C.; Glymour, M.; Yokoyama, J.; Elahi, F.; Rabinovici, G.; Miller, B.; Mormino, E.; Sperling, R.; Bennett, D.; McEvoy, L.; Brewer, J.; Feldman, H.; Posthuma, D.; Hyman, B.; Schellenberg, G.; Yaffe, K.; Andreassen, O.; Dale, A.; Sugrue, L.; Karch, C.; Desikan, R.

10.1101/383844 — genetics — Posted on 2018-08-03

2319 FACT activity and histone H3-K56 acetylation promote optimal establishment of chromatin architecture independent of ongoing transcription in Saccharomyces cerevisiae

McCullough, L.; Pham, T. H.; Parnell, T. J.; Chandrasekharan, M. B.; Stillman, D. J.; Formosa, T.

10.1101/383984 — genomics — Posted on 2018-08-03

2320 Evaluating the quality of the 1000 Genomes Project data

Belsare, S.; Sakin-Levy, M.; Mostovoy, Y.; Durinck, S.; Chaudhry, S.; Xiao, M.; Peterson, A. S.; Kwok, P.-Y.; Seshagiri, S.; Wall, J. D.

10.1101/383950 — genomics — Posted on 2018-08-03

2321 Reaction times and other skewed distributions: problems with the mean and the median

Rousselet, G. A.; Wilcox, R. R.

10.1101/383935 — neuroscience — Posted on 2018-08-02

2322 Ankyrin domain encoding genes resulting from an ancient horizontal transfer are functionally integrated into developmental gene regulatory networks in the wasp Nasonia

Lynch, J.; Pers, D.

10.1101/383968 — developmental biology — Posted on 2018-08-02

2323 High Aspect Ratio Nanomaterials Enable Delivery of Functional Genetic Material Without DNA Integration in Mature Plants

Demirer, G. S.; Zhang, H.; Matos, J.; Goh, N.; Cunningham, F. J.; Sung, Y.; Chang, R.; Aditham, A. J.; Chio, L.; Cho, M.-J.; Staskawicz, B.; Landry, M. P.

10.1101/179549 — plant biology — Posted on 2018-08-02

2324 Detection of Amyotrophic Lateral Sclerosis (ALS) via Acoustic Analysis

Norel, R.; Pietrowicz, M.; Agurto, C.; Rishoni, S.; Cecchi, G.

10.1101/383414 — neuroscience — Posted on 2018-08-02

2325 Identification of functional long non-coding RNAs in C. elegans

Akay, A.; Jordan, D.; Navarro, I. C.; Wrzesinski, T.; Ponting, C. P.; Miska, E. A.; Haerty, W.

10.1101/383919 — genetics — Posted on 2018-08-02

2326 Resolving Filament Level Mechanics in Collagen Networks using Activity Microscopy

Lissek, E. N.; Bartsch, T. F.; Florin, E.-L.

10.1101/382903 — biophysics — Posted on 2018-08-02

2327 Pooled optical screens in human cells

Feldman, D.; Singh, A.; Schmid-Burgk, J. L.; Mezger, A.; Garrity, A. J.; Carlson, R. J.; Zhang, F.; Blainey, P.

10.1101/383943 — genomics — Posted on 2018-08-02

2328 Sequential Specification of Oligodendrocyte and NG2 Cell Fates by Distinct Levels of Hedgehog Signaling

Appel, B.; Ravanelli, A.; Kearns, C.; Powers, R.; Wang, Y.; Hines, J.; Donaldson, M.

10.1101/377671 — developmental biology — Posted on 2018-08-02

2329 Static kinks or flexible hinges: conformational distributions of bent DNA bound to integration host factor mapped by fluorescence lifetime measurements

Connolly, M.; Arra, A.; Zvoda, V.; Steinbach, P. J.; Rice, P. A.; Ansari, A.

10.1101/382655 — biophysics — Posted on 2018-08-02

2330 Genotyping Polyploids from Messy Sequencing Data

Gerard, D.; Ferrao, L. F. V.; Garcia, A. A. F.; Stephens, M.

10.1101/281550 — bioinformatics — Posted on 2018-08-02

2331 Accurate estimation of single cell allele-specific gene expression using all reads and combining information across cells

Choi, K.; Raghupathy, N.; Churchill, G. A.

10.1101/383224 — bioinformatics — Posted on 2018-08-02

2332 Brain areas commonly activated and asymmetrical in production, listening and reading tasks at the word level: an fMRI study of 144 right-handers.

Hesling, I.; Labache, L.; Jobard, G.; Leroux, G.; Tzourio-Mazoyer, N.

10.1101/382960 — neuroscience — Posted on 2018-08-02

2333 Characterising RAG1 and RAG2 with predictive genomics

Lawless, D.; Allen Lango, H.; Thaventhiran, J.; Walter, J. E.; Anwar, R.; Savic, S.

10.1101/272609 — genomics — Posted on 2018-08-02

2334 Ancestry-dependent Enrichment of Deleterious Homozygotes in Runs of Homozygosity

Szpiech, Z. A.; Mak, A. C.; White, M. J.; Hu, D.; Eng, C.; Burchard, E. G.; Hernandez, R. D.

10.1101/382721 — genetics — Posted on 2018-08-02

2335 Muramyl endopeptidase Spr contributes to intrinsic vancomycin resistance in Salmonella enterica serovar Typhimurium

Vesto, K.; Huseby, D. L.; Snygg, I.; Wang, H.; Hughes, D.; Rhen, M.

10.1101/274886 — microbiology — Posted on 2018-08-02

2336 Antiviral genes are not rapidly evolving in Drosophila innubila

Hill, T.; Koseva, B.; Unckless, R. L.

10.1101/383877 — genomics — Posted on 2018-08-02

2337 Model-based analysis of positive selection significantly expands the list of cancer driver genes, including RNA methyltransferases

Zhao, S.; Liu, J.; Nanga, P.; Liu, Y.; Cicek, E.; Knoblauch, N.; He, C.; Stephens, M.; He, X.

10.1101/366823 — genomics — Posted on 2018-08-02

2338 Emergence of trait variability through the lens of nitrogen assimilation in Prochlorococcus

Berube, P. M.; Rasmussen, A.; Braakman, R.; Stepanauskas, R.; Chisholm, S. W.

10.1101/383927 — evolutionary biology — Posted on 2018-08-02

2339 A parameter-efficient deep learning approach to predict conversion from mild cognitive impairment to Alzheimer’s disease within three years

Spasov, S.; Passamonti, L.; Duggento, A.; Lio, P.; Toschi, N.

10.1101/383687 — bioinformatics — Posted on 2018-08-02

2340 A galling insect activates plant reproductive programs during gall development

Schultz, J. C.; Edger, P. P.; Body, M. J.; Appel, H. M.

10.1101/383851 — plant biology — Posted on 2018-08-02

2341 Individual differences in dopamine are associated with reward discounting in clinical groups but not in healthy adults

Castrellon, J. J.; Seaman, K. L.; Crawford, J. L.; Young, J. S.; Smith, C. T.; Dang, L. C.; Hsu, M.; Cowan, R. L.; Zald, D. H.; Samanez-Larkin, G. R.

10.1101/383810 — neuroscience — Posted on 2018-08-02

2342 Faded visual afterimages reappear after TMS over early visual cortex

Engelen, T.; Rademaker, R. L.; Sack, A. T.

10.1101/383893 — neuroscience — Posted on 2018-08-02

2343 A macrophage-based screen identifies antibacterial compounds selective for intracellular Salmonella Typhimurium

Ellis, M. J.; Tsai, C. N.; Johnson, J. W.; French, S.; Elhenawy, W.; Porwollik, S.; Andrews-Polymenis, H.; McClelland, M.; Magolan, J.; Coombes, B. K.; Brown, E. D.

10.1101/383828 — microbiology — Posted on 2018-08-02

2344 Rift Valley fever virus induces fetal demise through direct placental infection

McMillen, C. M.; Arora, N.; Boyles, D. A.; Albe, J. R.; Kujawa, M. R.; Bonadio, J. F.; Coyne, C. B.; Hartman, A. L.

10.1101/383745 — microbiology — Posted on 2018-08-02

2345 YcjW: a transcription factor that controls the emergency generator of H2S in E. coli.

Luhachack, L.; Shamovsky, I.; Nudler, E.

10.1101/383885 — microbiology — Posted on 2018-08-02

2346 Powerful and Efficient Strategies for Genetic Association Testing of Symptom and Questionnaire Data in Psychiatric Genetic Studies

Holleman, A. M.; Broadaway, K. A.; Duncan, R.; Almli, L. M.; Bradley, B.; Ressler, K. J.; Ghosh, D.; Mulle, J. G.; Epstein, M. P.

10.1101/383471 — genetics — Posted on 2018-08-02

2347 Torpor duration, more than temperature, is key to hummingbird nighttime energy savings

Shankar, A.; Schroeder, R. J.; Wethington, S. M.; Graham, C. H.; Powers, D. H.

10.1101/383679 — ecology — Posted on 2018-08-02

2348 Accurate Reference-Free Somatic Variant-Calling by Integrating Genomic, Sequencing and Population Data

Sun, R. X.; Lalansingh, C. M.; Espiritu, S. M. G.; Yao, C. Q.; Yamaguchi, T. N.; Prokopec, S. D.; Szyca, L.; Houlahan, K. E.; Heisler, L. E.; Black, M.; Li, C. H.; Barrett, J.; Nichols, A. C.; Boutros, P. C.

10.1101/383703 — bioinformatics — Posted on 2018-08-02

2349 Detection of Amyotrophic Lateral Sclerosis (ALS) via Acoustic Analysis

Noirel, R.; Pietrowicz, M.; Agurto, C.; Rishoni, S.; Cecchi, G.

10.1101/383414 — neuroscience — Posted on 2018-08-02

2350 Optimization of the DsRed fluorescent protein for use in Mycobacterium tuberculosis

Carroll, P.; Muwanguzi, J.; Parish, T.

10.1101/383836 — molecular biology — Posted on 2018-08-02

2351 Necessity and contingency in developmental genetic screens: LIN-3, Wnt and semaphorin pathways in vulval induction of the nematode Oscheius tipulae

Felix, M.-A.; Vargas Velazquez, A. M.; Besnard, F.

10.1101/383729 — genetics — Posted on 2018-08-02

2352 Disulfide bonds: the power switches of elastic proteins

Eckels, E. C.; Haldar, S.; Tapia-Rojo, R.; Rivas Pardo, J. A.; Fernandez, J. M.

10.1101/383711 — biophysics — Posted on 2018-08-02

2353 Mouse parabrachial neurons signal a relationship between bitter taste and nociceptive stimuli

Li, J.; Lemon, C.

10.1101/383661 — neuroscience — Posted on 2018-08-02

2354 Neural competitive queuing of ordinal structure underlies skilled sequential action

Kornysheva, K.; Bush, D.; Meyer, S.; Sadnicka, A.; Barnes, G.; Burgess, N.

10.1101/383364 — neuroscience — Posted on 2018-08-02

2355 (-)-Epigallocatechin-3-gallate inhibition of Epstein-Barr virus lytic replication involves latent membrane protein 1-mediated MAPK signaling pathways

Li, H.; Luo, X.; Hu, J.; Liu, S.; Li, N.; Tang, M.; Weng, X.; Yi, W.; Gao, J.; Bode, A.; Dong, Z.; Cao, Y.

10.1101/383497 — molecular biology — Posted on 2018-08-02

2356 Horizontal gene flow into Geobacillus is constrained by the chromosomal organization of growth and sporulation

Esin, A.; Ellis, T.; Warnecke, T.

10.1101/381442 — evolutionary biology — Posted on 2018-08-02

2357 Genetic deletion of genes in the cerebellar rhombic lip lineage can stimulate compensation through adaptive reprogramming of ventricular zone-derived progenitors

Wojcinski, A.; Morabito, M.; Lawton, A. K.; Stephen, D. N.; Joyner, A. L.

10.1101/383778 — developmental biology — Posted on 2018-08-02

2358 Where do animals covered by the US Animal Welfare Act live? Analysis of USDA licensed and registered entities

Bennett, A. J.; Schoenbeck, E. G.

10.1101/379412 — zoology — Posted on 2018-08-02

2359 Failure to learn during roving, analysing the unsupervised bias hypothesis.

Higgins, D.; Herzog, M.

10.1101/383398 — neuroscience — Posted on 2018-08-02

2360 PTGER2-β-Catenin Axis Links High Salt Environments to Autoimmunity by Balancing IFNγ and IL-10 in FoxP3+ Regulatory T cells

Sumida, T.; Lincoln, M. R.; Ukeje, C. M.; Rodriguez, D. M.; Akazawa, H.; Noda, T.; Naito, A. T.; Komuro, I.; Dominguez-Villar, M.; Hafler, D. A.

10.1101/379453 — immunology — Posted on 2018-08-02

2361 Dissection of complex, fitness-related traits in multiple Drosophila mapping populations offers insight into the genetic control of stress resistance

Everman, E.; McNeil, C.; Hackett, J.; Bain, C.; Macdonald, S. J.

10.1101/383802 — genetics — Posted on 2018-08-02

2362 The fitness consequences of genetic variation in wild populations of mice

Barrett, R. D. H.; Laurent, S.; Mallarino, R.; Pfeifer, S. P.; Xu, C. C. Y.; Foll, M.; Wakamatsu, K.; Duke-Cohan, J. S.; Jensen, J. D.; Hoekstra, H. E.

10.1101/383240 — evolutionary biology — Posted on 2018-08-02

2363 Gramicidin increases lipid flip-flop in symmetric and asymmetric lipid vesicles

Doktorova, M.; Heberle, F. A.; Marquardt, D.; Rusinova, R.; Sanford, L.; Peyear, T.; Katsaras, J.; Feigenson, G. W.; Weinstein, H.; Andersen, O. S.

10.1101/383463 — biophysics — Posted on 2018-08-02

2364 FactorialHMM: Fast and exact inference in factorial hidden Markov models

Schweiger, R.; Erlich, Y.; Carmi, S.

10.1101/383380 — bioinformatics — Posted on 2018-08-02

2365 Identification of microRNA-27a as a key regulator of cholesterol homeostasis

KHAN, A. A.; GUPTA, V.; ANANTHAMOHAN, K.; ARIGE, V.; REDDY, S.; BARTHWAL, M. K.; DIXIT, M.; REDDY, B.; MAHAPATRA, N. R.

10.1101/383448 — molecular biology — Posted on 2018-08-02

2366 DOT1L inhibition reveals a distinct class ofenhancers dependent on H3K79 methylation

Godfrey, L.; Crump, N. T.; Thorne, R.; Lau, I.-J.; Repapi, E.; Dimou, D.; Telenius, J.; Oudelaar, A. M.; Downes, D.; Vyas, P.; Hughes, J. R.; Milne, T. A.

10.1101/383489 — molecular biology — Posted on 2018-08-02

2367 Genomic analysis of diet composition finds novel loci and associations with health and lifestyle

Meddens, S. F. W.; de Vlaming, R.; Bowers, P.; Burik, C. A.; Karlsson Linner, R.; Lee, C.; Okbay, A.; Turley, P.; Rietveld, C. A.; Fontana, M. A.; Ghanbari, M.; Imamuri, F.; McMahon, G.; van der Most, P. J.; Voortman, T.; Wade, K. H.; Anderson, E. L.; Braun, K. V.; Emmett, P. M.; Esko, T.; Gonzalez, J. R.; Kiefte - de Jong, J. C.; Luan, J.; Langenberg, C.; Muka, T.; Ring, S.; Rivadeneira, F.; Schoufour, J. D.; Snieder, H.; van Rooij, F. J.; Wolffenbuttel, B. H.; Davey Smith, G.; Franco, O. H.; Forouhi, N. G.; Ikram, M. A.; Uitterlinden, A. G.; van Vliet - Ostaptchouk, J. V.; Wareham, N. J.; Ce

10.1101/383406 — genetics — Posted on 2018-08-02

2368 Genetic draft and valley crossing

Kessinger, T. A.; Van Cleve, J.

10.1101/383737 — evolutionary biology — Posted on 2018-08-02

2369 Inner lumen proteins stabilize doublet microtubules in cilia/flagella

Owa, M.; Uchihashi, T.; Yanagisawa, H.; Yamano, T.; Iguchi, H.; Fukuzawa, H.; Wakabayashi, K.-i.; Ando, T.; Kikkawa, M.

10.1101/383430 — cell biology — Posted on 2018-08-02

2370 Individual susceptibility to TMS affirms the precuneual role in meta-memory upon recollection

Ye, Q.; Zou, F.; Dayan, M.; Lau, H.; Hu, Y.; Kwok, S. C.

10.1101/383299 — neuroscience — Posted on 2018-08-02

2371 Cholesterol interaction sites on the transmembrane domain of the hedgehog signal transducer and Class F G protein-coupled receptor Smoothened

Hedger, G.; Koldsoe, H.; Chavent, M.; Siebold, C.; Rohatgi, R.; Sansom, M.

10.1101/383539 — biophysics — Posted on 2018-08-02

2372 Occipitotemporal Representations Reflect Individual Differences in Conceptual Knowledge

Braunlich, K.; Love, B. C.

10.1101/264895 — neuroscience — Posted on 2018-08-02

2373 Comparative RNA-seq based transcriptomic analysis of Aspergillus nidulans recombinant strains overproducing heterologous glycoside hydrolases

Calzado, F.; Zubieta, M. P.; Persinoti, G. F.; Terrasan, C. R.; Rubio, M. V.; Contesini, F. J.; Squina, F. M.; Damasio, A.

10.1101/241273 — microbiology — Posted on 2018-08-02

2374 Accounting for programmed ribosomal frameshifting in the computation of codon usage bias indices

Garcia, V.; Zoller, S.; Anisimova, M.

10.1101/293340 — genetics — Posted on 2018-08-02

2375 Genome-wide association study meta-analysis of the Alcohol Use Disorder Identification Test (AUDIT) in two population-based cohorts (N=141,932)

Sanchez-Roige, S.; Palmer, A. A.; Fontanillas, P.; Elson, S.; 23andMe Research Team, ; Substance Use Disorder Working Group of the Psychiatric Genomics Consortium, ; Adams, M. J.; Howard, D. M.; Edenberg, H. J.; Davies, G.; Crist, R. C.; Deary, I.; McIntosh, A. M.; Clarke, T. K.

10.1101/275917 — genetics — Posted on 2018-08-02

2376 Fast fronto-parietal cortical dynamics of conflict detection and context updating in a flanker task

Brydges, C. R.; Barcelo, F.; Nguyen, A. T.; Fox, A. M.

10.1101/336958 — neuroscience — Posted on 2018-08-02

2377 Manipulation of subcortical and deep cortical activity in the primate brain using transcranial focused ultrasound stimulation

Folloni, D.; Verhagen, L.; Mars, R. B.; Fouragnan, E.; Constans, C.; Aubry, J.-F.; Rushworth, M. F. S.; Sallet, J.

10.1101/342303 — neuroscience — Posted on 2018-08-02

2378 Combining Deep Learning and Active Contours Opens The Way to Robust, Automated Analysis of Brain Cytoarchitectonics

Thierbach, K.; Bazin, P.-L.; De Back, W.; Gavriilidis, F.; Kirilina, E.; Jaeger, C.; Morawski, M.; Geyer, S.; Weiskopf, N.; Scherf, N.

10.1101/297689 — bioinformatics — Posted on 2018-08-02

2379 No evidence that predictions and attention modulate the first feedforward sweep of cortical information processing

Alilovic, J.; Timmermans, B.; Reteig, L. C.; Gaal, S. v.; Slagter, H. A.

10.1101/351965 — neuroscience — Posted on 2018-08-02

2380 Repeated evolution of asexuality involves convergent gene expression changes

Parker, D. J.; Bast, J.; Jalvingh, K.; Dumas, Z.; Robinson-Rechavi, M.; Schwander, T.

10.1101/364869 — evolutionary biology — Posted on 2018-08-02

2381 ACBD3 is an essential pan-enterovirus host factor that mediates the interaction between viral 3A protein and cellular protein PI4KB

Lyoo, H.; van der Schaar, H. M.; Dorobantu, C. M.; Strating, J. R. P. M.; van Kuppeveld, F. J. M.

10.1101/375550 — microbiology — Posted on 2018-08-02

2382 Conserved SQ and QS motifs in bacterial effectors suggest pathogen interplay with the ATM kinase family during infection

Sampietro, D.; Samano-Sanchez, H.; Davey, N. E.; Sharan, M.; Meszaros, B.; Gibson, T. J.; Kumar, M.

10.1101/364117 — bioinformatics — Posted on 2018-08-02

2383 Healthspan pathway maps in C. elegans and humans highlight transcription, prolifera-tion/biosynthesis and lipids

Moeller, S.; Saul, N.; Cohen, A. A.; Koehling, R.; Sender, S.; Murua Escobar, H.; Junghanss, C.; Cirulli, F.; Berry, A.; Antal, P.; Adler, P.; Vilo, J.; Boiani, M.; Jansen, L.; Repsilber, D.; Grabe, H. J.; Struckmann, S.; Barrantes, I.; Hamed, M.; Wouters, B.; Schoofs, L.; Luyten, W.; Fuellen, G.

10.1101/355131 — bioinformatics — Posted on 2018-08-02

2384 Sympatric and allopatric evolutionary contexts shape differential immune response in Biomphalaria / Schistosoma interaction

Portet, A.; Pinaud, S.; Chaparro, C.; Galinier, R.; Charriere, G.; Allienne, J.-F.; Duval, D.; Gourbal, B.

10.1101/378034 — immunology — Posted on 2018-08-02

2385 O-fucosylation of thrombospondin-like repeats is required for processing of MIC2 and for efficient host cell invasion by Toxoplasma gondii tachyzoites

Bandini, G.; Leon, D. R.; Hoppe, C. M.; Zhang, Y.; Agop-Nersesian, C.; Shears, M. J.; Mahal, L. K.; Routier, F. H.; Costello, C. E.; Samuelson, J.

10.1101/382515 — microbiology — Posted on 2018-08-02

2386 Need for high-resolution Genetic Analysis in iPSC: Results and Lessons from the ForIPS Consortium

Popp, B.; Krumbiegel, M.; Grosch, J.; Sommer, A.; Uebe, S.; Kohl, Z.; Ploetz, S.; Farrell, M.; Trautmann, U.; Kraus, C.; Ekici, A. B.; Asadollahi, R.; Regensburger, M.; Guenther, K.; Rauch, A.; Edenhofer, F.; Winkler, J.; Winner, B.; Reis, A.

10.1101/379818 — genomics — Posted on 2018-08-02

2387 The genetic basis of diurnal preference in Drosophila melanogaster

Pegoraro, M.; Flavell, L. M.; Menegazzi, P.; Colombi, P.; Dao, P.; Charlotte Helfrich-Förster, C.; Tauber, E.

10.1101/380733 — evolutionary biology — Posted on 2018-08-02

2388 Item-specific delay activity demonstrates concurrent storage of multiple items in working memory

Sutterer, D. W.; Foster, J. J.; Adam, K. C. S.; Vogel, E. K.; Awh, E.

10.1101/382879 — neuroscience — Posted on 2018-08-02

2389 Ezetimibe inhibits Dengue virus infection in Huh 7 cells by blocking the cholesterol transporter Niemann-Pick C1-like 1 receptor

Osuna-Ramos, J. F.; Reyes-Ruiz, J. M.; Bautista-Carbajal, P.; Farfan-Morales, N.; Cervantes-Salazar, M.; del Angel, R. M.

10.1101/382747 — microbiology — Posted on 2018-08-02

2390 Did a novel virus contribute to late blight epidemics?

Cai, G.; Meyers, K.; Fry, W. E.; Hillman, B. I.

10.1101/383653 — pathology — Posted on 2018-08-02

2391 Theileria highjacks JNK2 into a complex with the macroschizont GPI-anchored surface protein p104

Latre de Late, P.; Haidar, M.; Ansari, H.; Tajeri, S.; Szarka, E.; Alexa, A.; Woods, K.; Remenyi, A.; Pain, A.; Langsley, G.

10.1101/383646 — microbiology — Posted on 2018-08-02

2392 TreeN93: a non-parametric distance-based method for inferring viral transmission clusters

Moshiri, N.

10.1101/383190 — bioinformatics — Posted on 2018-08-02

2393 Manipulation of the social and spatial organization of the vector of Chagas disease, Triatoma infestans, by the parasite Trypanosoma cruzi

Depickere, S.; Ramirez-Avila, G. M.; Deneubourg, J.-L.

10.1101/383620 — animal behavior and cognition — Posted on 2018-08-02

2394 Distinguishing between parallel and serial processing in visual attention from neurobiological data

Li, K.; Kadohisa, M.; Kusunoki, M.; Duncan, J.; Bundesen, C.; Ditlevsen, S.

10.1101/383596 — neuroscience — Posted on 2018-08-02

2395 Toxoplasma gondii ROP18 Inhibits Human Glioblastoma Cell Apoptosis through Mitochondrial Pathway by Targeting Host Cell P2X1

Zhou, L.-J.; Chen, M.; He, C.; Xia, J.; He, c.; Deng, S. Q.; Peng, H.-J.

10.1101/383638 — molecular biology — Posted on 2018-08-02

2396 ITPase Deficiency Causes Martsolf Syndrome With a Lethal Infantile Dilated Cardiomyopathy

FitzPatrick, D. R.; Handley, M. T.; Reddy, K.; Wills, J.; Rosser, E.; Kamath, A.; Halachev, M.; Falkous, G.; Williams, D.; Cox, P.; Meynert, A.; Raymond, E. S.; Morrison, H.; Brown, S.; Allan, E.; Aligianis, I.; Jackson, A. P.; Ramsahoye, B. H.; von Kriegsheim, A.; Taylor, R. W.; Finch, A. J.

10.1101/383612 — genetics — Posted on 2018-08-02

2397 Opposing Roles of the Fork-head box genes FoxM1 and FoxA2 in Hepatocellular Carcinoma

Raychaudhuri, P.; Chand, V.; Pandey, A.; Kopanja, D.; Guzman, G.

10.1101/383604 — cancer biology — Posted on 2018-08-02

2398 Genetic diversity of the enteroviruses detected from Cerebrospinal fluid (CSF) samples of patients with suspected aseptic meningitis in northern West Bank, Palestine in 2017

Dumaidi, K.; Al-Jawabreh, A.; Samarah, F.; Zraiqi, A.; Yaseen, D.

10.1101/383554 — molecular biology — Posted on 2018-08-02

2399 The role of sodium channels in sudden unexpected death in pediatrics

Rochtus, A. M.; Goldstein, R. D.; Holm, I. A.; Brownstein, C. A.; Perez-Palma, E.; Lal, D.; Poduri, A.

10.1101/383562 — genetics — Posted on 2018-08-02

2400 Using an Optimal Set of Features with a Machine Learning-Based Approach to Predict Effector Proteins for Legionella pneumophila

Esna Ashari, Z.; Brayton, K. A.; Broschat, S. L.

10.1101/383570 — bioinformatics — Posted on 2018-08-02

2401 Encircling the regions of the pharmacogenomic landscape that determine drug response

Fernandez-Torras, A.; Duran-Frigola, M.; Aloy, P.

10.1101/383588 — bioinformatics — Posted on 2018-08-02

2402 Changes in rumen microbiota of cows in response to dietary supplementation with nitrate, linseed and saponin alone or in combination.

Popova, M.; Guyader, J.; Silberberg, M.; Seradj, A. R.; Saro, C.; Bernard, A.; Gerard, C.; Martin, C.; Morgavi, D. P.

10.1101/383067 — molecular biology — Posted on 2018-08-02

2403 A scoping review of health-based survey instruments validated in Brunei Darussalam

Alhaji, M. M.; Tan, J.; Naing, L.; Tuah, N. A.

10.1101/383547 — epidemiology — Posted on 2018-08-02

2404 Nitric oxide synthase-mediated early nitric oxide-burst alleviates drought-induced oxidative damage in ammonium supplied-rice roots

Cao, X.; Zhu, C.; Zhong, C.; Zhang, J.; Zhu, L.; Wu, L.; Ma, Q.; Jin, Q.

10.1101/383323 — physiology — Posted on 2018-08-02

2405 Functional dynamics underlying near-threshold perception of facial emotions: a magnetoencephalography investigation.

Kajal, D. S.; Fioravanti, C.; Elshahabi, A.; Ruiz, S.; Sitaram, R.; Braun, C.

10.1101/383315 — neuroscience — Posted on 2018-08-02

2406 Mesenchymal Stem Cell Chondroinduction on Cellulose-Silk Composites is Driven by Substrate Elasticity

Begum, R.; Kafienah, W.

10.1101/383307 — bioengineering — Posted on 2018-08-02

2407 Information-theoretical approach to measuring landscape complexity

Nowosad, J.; Stepinski, T.

10.1101/383281 — ecology — Posted on 2018-08-02

2408 Drosophila small ovary gene ensures germline stem cell maintenance and differentiation by silencing transposons and organising heterochromatin

Jankovics, F.; Bence, M.; Sinka, R.; Farago, A.; Bodai, L.; Pettko-Szandtner, A.; Ibrahim, K.; Takacs, Z.; Szarka-Kovacs, A. B.; Erdelyi, M.

10.1101/383265 — developmental biology — Posted on 2018-08-02

2409 More than black and white: complex relationships involving serine proteases regulate the Toll pathway and the melanization response in Drosophila

Dudzic, J. P.; Hanson, M. A.; Iatsenko, I.; Kondo, S.; Lemaitre, B.

10.1101/383257 — immunology — Posted on 2018-08-02

2410 Epigenetic findings in periodontitis in UK twins: a cross sectional study

Kurushima, Y.; Tsai, P.-C.; Castillo-Fernandez, J. E.; Couto Alves, A.; El-Sayed Moustafa, J. S.; Le Roy, C.; Ide, M.; Hughes, F. J.; Small, K.; Steves, C. J.; Bell, J. T.

10.1101/381327 — genomics — Posted on 2018-08-02

2411 The borders of cis-regulatory DNA sequences harbor the divergent transcription factor binding motifs in the human genome

Huang, J.-H.; Kwan, R. S.-Y.; Tsai, Z. T.-Y.; Tsai, H.-K.

10.1101/383182 — genomics — Posted on 2018-08-02

2412 Curcumin inhibits cystogenesis in autosomal dominant polycystic kidney disease cells via altering JAK2/STAT3 activity.

Patera, F.; Cudzuch-Mardy, A.; Huang, Z.; Fragiadaki, M.

10.1101/378919 — cell biology — Posted on 2018-08-02

2413 Accurate estimation of single cell allele-specific gene expression using all reads and combining information across cells

Choi, K.; Raghupathy, N.; Churchill, G. A.

10.1101/383224 — bioinformatics — Posted on 2018-08-02

2414 Nanoscale investigation in 3D scaffolds of cell-material interactions for tissue-engineering

Iandolo, D.; Pennacchio, F. A.; Mollo, V.; Rossi, D.; Dannhauser, D.; Cui, B.; Owens, R. M.; Santoro, F.

10.1101/383117 — bioengineering — Posted on 2018-08-02

2415 A non-canonical chemical feedback self-limits nitric oxide-cyclic GMP signaling in health and disease

Dao, T.-V.; Deile, M.; Nedvetsky, P. I.; Meens, M.; Güldner, A.; Ibarra, C.; Gödecke, A.; Schmidt, H. H. H. W.

10.1101/383208 — pharmacology and toxicology — Posted on 2018-08-02

2416 Computational model for human 3D shape perception from a single specular image

Shimokawa, T.; Nishio, A.; Sato, M.-a.; Kawato, M.; Komatsu, H.

10.1101/383174 — neuroscience — Posted on 2018-08-02

2417 CryoEM structures of MDA5-dsRNA filaments at different stages of ATP hydrolysis

Yu, Q.; Qu, K.; Modis, Y.

10.1101/376319 — immunology — Posted on 2018-08-02

2418 Differential effects of conspecific and heterospecific density on the development of Aedes aegypti and Aedes albopictus larvae

Paton, R.; Heath, K.; Wilson, A.; Bonsall, M.

10.1101/383125 — ecology — Posted on 2018-08-02

2419 Polymer coil-globule phase transition is a universal folding principle of Drosophila epigenetic domains

Lesage, A.; Dahirel, V.; Victor, J.-M.; Barbi, M.

10.1101/383158 — biophysics — Posted on 2018-08-02

2420 PconsC4: fast, free, easy, and accurate contact predictions.

Michel, M.; Menendez Hurtado, D.; Elofsson, A.

10.1101/383133 — bioinformatics — Posted on 2018-08-02

2421 TreeN93: a non-parametric distance-based method for inferring viral transmission clusters

Moshiri, N.

10.1101/383190 — bioinformatics — Posted on 2018-08-02

2422 LINE-2 transposable elements are a source for functional human microRNAs and target sites.

Petri, R.; Brattas, P. L.; Sharma, Y.; Jönsson, M. E.; Pircs, K.; Bengzon, J.; Jakobsson, J.

10.1101/218842 — genomics — Posted on 2018-08-02

2423 Sharing of heteroplasmies between human liver lobes varies across the mtDNA genome

Wachsmuth, M.; Huebner, A.; Schroeder, R.; Li, M.; Eis-Huebinger, A. M.; Madea, B.; Stoneking, M.

10.1101/155796 — genetics — Posted on 2018-08-02

2424 Faster processing of moving compared to flashed bars in awake macaque V1 provides a neural correlate of the flash lag illusion

Subramaniyan, M.; Ecker, A. S.; Patel, S. S.; Cotton, J. R.; Bethge, M.; Pitkow, X.; Berens, P.; Tolias, A. S.

10.1101/031146 — neuroscience — Posted on 2018-08-02

2425 The potential aroma and flavor compounds in Vitis sp. cv. Koshu and V. vinifera L. cv. Chardonnay under different environmental conditions

Garrido, S. M. B.; Ohama, T.; Suehiro, Y.; Hata, Y.; Isogai, A.; Iwashita, K.; Yamamoto, N. G.; Koyama, K.

10.1101/383000 — plant biology — Posted on 2018-08-02

2426 Unlocking a high bacterial diversity in the coralloid root microbiome from the cycad genus Dioon

Suarez-Moo, P. d. J.; Vovides, A.; Griffith, M. P.; Barona-Gomez, F.; Cibrian-Jaramillo, A.

10.1101/381798 — microbiology — Posted on 2018-08-02

2427 Brain areas commonly activated and asymmetrical in production, listening and reading tasks at the word level: an fMRI study of 144 right-handers.

Hesling, I.; Labache, L.; Jobard, G.; Leroux, G.; Tzourio-Mazoyer, N.

10.1101/382960 — neuroscience — Posted on 2018-08-02

2428 Dopamine Depletion Alters Macroscopic Network Dynamics in Parkinsons Disease

Shine, J. M.; Bell, P. T.; Matar, E.; Poldrack, R.; Lewis, S. J.; Halliday, G.; O'Callaghan, C.

10.1101/382994 — neuroscience — Posted on 2018-08-02

2429 Descriptions of four new species of Minyomerus Horn, 1876 sec. Jansen & Franz, 2018 (Coleoptera: Curculionidae), with notes on their distribution and phylogeny

Jansen, M. A.; Franz, N. M.

10.1101/383091 — evolutionary biology — Posted on 2018-08-02

2430 Detecting Large Indels Using Optical Map Data

Fan, X.; Xu, J.; Nakhleh, L.

10.1101/382986 — bioinformatics — Posted on 2018-08-02

2431 Brood-holding causes workers to pay attention to the queen in the carpenter ant Camponotus japonicus

Hara, K.

10.1101/383059 — animal behavior and cognition — Posted on 2018-08-02

2432 Individual slow wave morphology is a marker of ageing

Ujma, P. P.; Simor, P.; Steiger, A.; Dresler, M.; Bodizs, R.

10.1101/374397 — neuroscience — Posted on 2018-08-02

2433 L. pneumophila deploys a self-active inhibitor for inter-Legionella competition

Levin, T. C.; Goldspiel, B. P.; Malik, H. S.

10.1101/383018 — microbiology — Posted on 2018-08-02

2434 Inter-species differences in response to hypoxia in iPSC-derived cardiomyocytes from humans and chimpanzees

Ward, M. C.; Gilad, Y.

10.1101/382895 — genomics — Posted on 2018-08-02

2435 ShinyAIM: Shiny-based Application of Interactive Manhattan Plots for Longitudinal Genome-Wide Association Studies

Hussain, W.; Campbell, M.; Walia, H.; Morota, G.

10.1101/383026 — genetics — Posted on 2018-08-02

2436 Elysium: RNA-seq Alignment in the Cloud

Lachmann, A.; Xie, Z.; Ma'ayan, A.

10.1101/382937 — bioinformatics — Posted on 2018-08-02

2437 Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein S1

Beckert, B.; Turk, M.; Czech, A.; Berninghausen, O.; Beckmann, R.; Ignatova, Z.; Plitzko, J. M.; Wilson, D. N.

10.1101/382572 — molecular biology — Posted on 2018-08-02

2438 Integrative Transcription Start Site Analysis and Physiological Phenotyping Reveal Torpor-Specific Expressions in Mouse Skeletal Muscle

Sunagawa, G. A.; Deviatiiarov, R.; Ishikawa, K.; Gazizova, G.; Gusev, O.; Takahashi, M.

10.1101/374975 — physiology — Posted on 2018-08-02

2439 Delivery of GalNAc-conjugated splice-switching ASOs to non-hepatic cells through ectopic expression of asialoglycoprotein receptor

Scharner, J.; Qi, S.; Rigo, F.; Bennett, C. F.; Krainer, A. R.

10.1101/382606 — molecular biology — Posted on 2018-08-02

2440 HIV-1 evasion of restriction factors: cyclophilin A and cell fusion provide a helping hand.

Owen, H. A.; Vaughan-Jackson, A.; Nussbaum, L.; Vowles, J.; James, W. S.; Moore, M. D.

10.1101/383075 — microbiology — Posted on 2018-08-02

2441 Deficiency of the Endocytic Protein Hip1 Leads to Decreased Gdpd3 expression, Low Phosphocholine, and Kypholordosis

wijayatunge, R.; Holmstrom, S. r.; foley, s. b.; mgbemena, v. e.; bhargava, v.; perez, g. l.; mccrum, k.; ross, T. S.

10.1101/383083 — genetics — Posted on 2018-08-02

2442 Masculinity and the mechanisms of human self-domestication

Gleeson, B. T.

10.1101/143875 — evolutionary biology — Posted on 2018-08-01

2443 A Genome-Wide Association Study Reveals a Novel Regulator of Ovule Number and Fertility in Arabidopsis thaliana

Yuan, J.; Kessler, S. A.

10.1101/356600 — plant biology — Posted on 2018-08-01

2444 Multi-scale analysis of schizophrenia risk loci: Integrating centenarian genomes and spatio-temporal expression profiles suggest the need for adjunctive therapeutic interventions for neuropsychiatric disorders.

Chellappa S, A.; Pathak, A. K.; Sinha, P.; Jainarayanan, A. K.; Jain, S.; Brahmachari, S. K.

10.1101/369090 — bioinformatics — Posted on 2018-08-01

2445 Diverse endogenous retroviruses generate structural variation between human genomes via LTR recombination

Thomas, J.; Perron, H.; Feschotte, C.

10.1101/382630 — genetics — Posted on 2018-08-01

2446 Profiling the surface proteome identifies actionable biology for TSC1 mutant cells beyond mTORC1 signaling

Wei, J.; Leung, K. K.; Truillet, C.; Ruggero, D.; Wells, J. A.; Evans, M. J.

10.1101/382929 — cancer biology — Posted on 2018-08-01

2447 Brain folding is initiated by mechanical constraints without a cellular pre-pattern

Lawton, A. K.; Engstrom, T.; Rohrbach, D.; Omura, M.; Turnbull, D. H.; Mamou, J.; Zhang, T.; Schwarz, J. M.; Joyner, A. L.

10.1101/382887 — developmental biology — Posted on 2018-08-01

2448 Moving in complex environments: a biomechanical analysis of locomotion on inclined and narrow substrates

Clemente, C. J.; Dick, T. J. M.; Wheatley, R.; Gaschk, J.; Nasir, A. F. A. A.; Cameron, S. F.; Wilson, R. S.

10.1101/382028 — zoology — Posted on 2018-08-01

2449 Benchmarking Time-Series Data Discretization on Inference Methods

Li, Y.; Jann, T.; Vera-Licona, P.

10.1101/378620 — systems biology — Posted on 2018-08-01

2450 Behavioral response to visual motion impacts population coding in the mouse visual thalamus

Socha, K.; Whiteway, M.; Butts, D.; Bonin, V.

10.1101/382671 — neuroscience — Posted on 2018-08-01

2451 Interaction information along lifespan of the resting brain dynamics reveals a major redundant role of the default mode network

Camino-Pontes, B.; Diez, I.; Jimenez-Marin, A.; Rasero, J.; Bonifazi, P.; Stramaglia, S.; Swinnen, S.; Cortes, J. M.

10.1101/382705 — neuroscience — Posted on 2018-08-01

2452 Increased influence of periphery on central visual processing in humans during walking

Cao, L.; Haendel, B.

10.1101/382093 — neuroscience — Posted on 2018-08-01

2453 Episodic Memory Can Replace Active Storage in Visual Working Memory

Schurgin, M. W.; Cunningham, C. A.; Egeth, H. E.; Brady, T. F.

10.1101/381848 — neuroscience — Posted on 2018-08-01

2454 Exploring the prediction of emotional valence and pharmacologic effect across fMRI studies of antidepressants.

Barron, D. S.; Salehi, M.; Browning, M.; Harmer, C.; Constable, R.; Duff, E.

10.1101/382408 — neuroscience — Posted on 2018-08-01

2455 Task activations produce spurious but systematic inflation of task functional connectivity estimates

Cole, M. W.; Ito, T.; Schultz, D.; Mill, R.; Chen, R.; Cocuzza, C.

10.1101/292045 — neuroscience — Posted on 2018-08-01

2456 Effect of real-time video feedback on the gait foot placement regularity and symmetry in individuals with trans-tibial amputation: A case study

Mehdizadeh, S.; Nabavi, H.; Navvab Motlagh, F.; Osqueizadeh, R.

10.1101/381996 — neuroscience — Posted on 2018-08-01

2457 Item-specific delay activity demonstrates concurrent storage of multiple items in working memory

Sutterer, D. W.; Foster, J. J.; Adam, K. C. S.; Vogel, E. K.; Awh, E.

10.1101/382879 — neuroscience — Posted on 2018-08-01

2458 Synapse-selective control of cortical maturation and plasticity engages an interneuron-autonomous synaptic switch

Ribic, A.; Crair, M.; Biederer, T.

10.1101/382614 — neuroscience — Posted on 2018-08-01

2459 Nanopore-based DNA sequencing in clinical microbiology: preliminary assessment of basic requirements

Harstad, H.; Ahmad, R.; Bredberg, A.

10.1101/382580 — microbiology — Posted on 2018-08-01

2460 Ezetimibe inhibits Dengue virus infection in Huh 7 cells by blocking the cholesterol transporter Niemann-Pick C1 like 1 receptor

Osuna-Ramos, J. F.; Reyes-Ruiz, J. M.; Bautista-Carbajal, P.; Farfan-Morales, N.; Cervantes-Salazar, M.; del Angel, R. M.

10.1101/382747 — microbiology — Posted on 2018-08-01

2461 Interspecies malate-pyruvate shuttle drives amino acid exchange in organohalide-respiring microbial communities

Wang, P.-H.; Correia, K.; Ho, H.-C.; Venayak, N.; Nemr, K.; Flick, R.; Mahadevan, R.; Edwards, E. A.

10.1101/379438 — microbiology — Posted on 2018-08-01

2462 A Novel in vivo Model of Anaerobic Infection: The Investigation of Clostridium perfringens in Galleria mellonella Larvae.

Kay, S. J.; Edwards, J. R.; Brown, J. C. S.; Dixon, R. A.

10.1101/382077 — microbiology — Posted on 2018-08-01

2463 O-fucosylation of thrombospondin-like repeats is required for processing of MIC2 and for efficient host cell invasion by Toxoplasma gondii tachyzoites

Bandini, G.; Leon, D. R.; Hoppe, C. M.; Zhang, Y.; Agop-Nersesian, C.; Shears, M. J.; Mahal, L. K.; Routier, F. H.; Costello, C. E.; Samuelson, J.

10.1101/382515 — microbiology — Posted on 2018-08-01

2464 Insights from Comparison of the Renal and Skin Single Cell Transcriptomes in Lupus Nephritis

Der, E.; Suryawanshi, H.; Morozov, P.; Kustagi, M.; Goilav, B.; Ranabathou, S.; Izmirly, P.; Clancy, R.; Belmont, H. M.; Koenigsberg, M.; Mokrzycki, M.; Rominieki, H.; Graham, J.; Rocca, J.; Bornkamp, N.; Jordan, N.; Schulte, E.; Wu, M.; Pullman, J.; Slowikowski, K.; Raychaudhuri, S.; Guthridge, J.; James, J.; Acclerating Medicine Partnership (AMP), ; Buyon, J.; Tuschl, T.; Putterman, C.

10.1101/382846 — immunology — Posted on 2018-08-01

2465 Triggering MSR1 promotes JNK-mediated inflammation in IL-4 activated macrophages

Guo, M.; Hartlova, A.; Gierlinski, M.; Prescott, A.; Castellvi, J.; Hernandez Losa, J.; D. Dill, B.; H. Emmerich, C.; Ramon y Cajal, S.; G. Russell, D.; Trost, M.

10.1101/382853 — immunology — Posted on 2018-08-01

2466 Emergence and features of the multipartite genome structure of the family Burkholderiaceae revealed through comparative and evolutionary genomics

diCenzo, G. C.; Mengoni, A.; Perrin, E.

10.1101/382267 — genomics — Posted on 2018-08-01

2467 DNA methylation signatures of a large cohort monozygotic twins clinically discordant for multiple sclerosis

Souren, N. Y.; Gerdes, L. A.; Lutsik, P.; Gasparoni, G.; Beltran, E.; Salhab, A.; Kumpfel, T.; Weichenhan, D.; Plass, C.; Hohlfeld, R.; Walter, J.

10.1101/381822 — genomics — Posted on 2018-08-01

2468 Widespread genome instability in Solanum tuberosum plants regenerated from protoplasts

Fossi, M.; Comai, L.

10.1101/382861 — genomics — Posted on 2018-08-01

2469 Desiccation-induced changes in recombination rate and interference in fruit flies: an evidence for fitness-dependent plasticity

Aggarwal, D. D.; Rybnikov, S. R.; Cohen, I.; Rashkovetsky, E.; Michalak, P.; Korol, A. B.

10.1101/382259 — genetics — Posted on 2018-08-01

2470 H3K9me3 is Required for Transgenerational Inheritance of Small RNAs that Target a Unique Subset of Newly Evolved Genes

Lev, I.; Gingold, H.; Rechavi, O.

10.1101/338582 — genetics — Posted on 2018-08-01

2471 Genetic and phenotypic differentiation of lumpfish (Cyclopterus lumpus) across the North Atlantic: implications for conservation and aquaculture

Whittaker, B. A.; Consuegra, S.; Garcia de Leaniz, C.

10.1101/382119 — genetics — Posted on 2018-08-01

2472 The genomic and molecular basis of response to selection for longer limbs in mice

Castro, J. L. P.; Yancoskie, M. N.; Marchini, M.; Belohlavy, S.; Kucka, M.; Beluch, W. H.; Naumann, R.; Skuplik, I.; Cobb, J.; Barton, N. H.; Rolian, C.; Chan, Y. F.

10.1101/378711 — evolutionary biology — Posted on 2018-08-01

2473 Demographic inference using particle filters for continuous Markov jump processes

Henderson, D.; Zhu, S.; Lunter, G.

10.1101/382218 — evolutionary biology — Posted on 2018-08-01

2474 Cell type-specific structural plasticity of the ciliary transition zone in C. elegans

Akella, J. S.; Silva, M. S.; Morsci, N. S.; Nguyen, K. C. Q.; Rice, W.; Hall, D. H.; Barr, M. M.

10.1101/382689 — cell biology — Posted on 2018-08-01

2475 SSU72 phosphatase is a telomere replication terminator

Escandell, J. M.; Mascarenhas Carvalho, E. S.; Gallo-Fernandez, M.; Reis, C.; Matmati, S.; Matias Luis, I.; Abreu, I.; Coulon, S.; Godinho Ferreira, M.

10.1101/382564 — cell biology — Posted on 2018-08-01

2476 A Novel Scavenging Tool for Cancer Biomarker Discovery based on the Blood-Circulating Nanoparticle Protein Corona

Hadjidemetriou, M.; Al-Ahmady, Z.; Buggio, M.; Swift, J.; Kostarelos, K.

10.1101/382192 — cancer biology — Posted on 2018-08-01

2477 Electrodiffusion model of synaptic potentials in dendritic spines

Lagache, T.; Jayant, K.; Yuste, R.

10.1101/274373 — biophysics — Posted on 2018-08-01

2478 Can transcranial electric stimulation with multiple electrodes reach deep targets?

Huang, Y.; Parra, L. C.

10.1101/382598 — biophysics — Posted on 2018-08-01

2479 SciPipe - A workflow library for agile development of complex and dynamic bioinformatics pipelines

Lampa, S.; Dahlö, M.; Alvarsson, J.; Spjuth, O.

10.1101/380808 — bioinformatics — Posted on 2018-08-01

2480 Insights on protein thermal stability: a graph representation of molecular interactions

Miotto, M.; Olimpieri, P. P.; Di Rienzo, L.; Ambrosetti, F.; Corsi, P.; Lepore, R.; Tartaglia, G. G.; Milanetti, E.

10.1101/354266 — bioinformatics — Posted on 2018-08-01

2481 Characterizing Activity and Thermostability of GH5 Cellulase Chimeras from Mesophilic and Thermophilic Parents

Zheng, F.; Vermaas, J. V.; Zheng, J.; Wang, Y.; Tu, T.; Wang, X.; Xie, X.; Yao, B.; Beckham, G. T.; Luo, H.

10.1101/382069 — bioengineering — Posted on 2018-08-01

2482 An Ishihara-style test of animal colour vision

Cheney, K. L.; Green, N.; Vibert, A.; Vorobyev, M.; Marshall, J. N.; Osorio, D. C.; Endler, J. A.

10.1101/382051 — animal behavior and cognition — Posted on 2018-08-01

2483 Rho-mediated MRTF and YAP1 activation contributes to BRAF inhibitor resistance in Sox9High/Sox10Low melanoma cells.

Misek, S. A.; Appleton, K. M.; Dexheimer, T. S.; Lisabeth, E. M.; Lo, R.; Larsen, S. D.; Gallo, K.; Neubig, R. R.

10.1101/381806 — cancer biology — Posted on 2018-08-01

2484 Skin Lesion Classification Via Combining Deep Learning Features and Clinical Criteria Representations

Li, X.; Wu, J.; Jiang, H.; Chen, E. Z.; Dong, X.; Rong, R.

10.1101/382010 — bioinformatics — Posted on 2018-08-01

2485 Approach direction prior to landing explains patterns of colour learning in bees

Langridge, K. V.; Wilke, C.; Riabinina, O.; Vorobyev, M.; Hempel de Ibarra, N.

10.1101/381210 — animal behavior and cognition — Posted on 2018-08-01

2486 Isoform-specific NADPH oxidase inhibition for pharmacological target validation

Dao, T.-V.; Altenhöfer, S.; Elbatreek, M. H.; Casas, A. I.; Lijnen, P.; Meens, M. J.; Knaus, U.; Schmidt, H. H. H. W.

10.1101/382226 — pharmacology and toxicology — Posted on 2018-08-01

2487 Competition between mobile genetic elements drives optimization of a phage-encoded CRISPR-Cas system: Insights from a natural arms-race

McKitterick, A.; LeGault, K.; Angermeyer, A.; Alam, M.; Seed, K.

10.1101/381962 — microbiology — Posted on 2018-08-01

2488 Diagnostic value of blood gene expression-based classifiers as exemplified for acute myeloid leukemia

Warnat-Herresthal, S.; Perrakis, K.; Taschler, B.; Becker, M.; Seep, L.; Bassler, K.; Guenther, P.; Schulte-Schrepping, J.; Klee, K.; Ulas, T.; Haferlach, T.; Mukherjee, S.; Schultze, J. L.

10.1101/382143 — genomics — Posted on 2018-08-01

2489 Structure mapping of dengue and Zika viruses reveals new functional long-range interactions

Huber, R. G.; Lim, X. N.; Ng, W. C.; Sim, A.; Poh, H. X.; Shen, Y.; Lim, S. Y.; Sundstrom, A. K. B.; Sun, X.; Aw, J. G.; Too, H. K.; Boey, P. H.; Wilm, A.; Chawla, T.; Choy, M. J.; Jiang, L.; Sessions, P. F.; Loh, X. J.; Alonso, S.; Hibberd, M.; Nagarajan, N.; Ooi, E. E.; Bond, P. J.; Sessions, O. M.; Wan, Y.

10.1101/381368 — genomics — Posted on 2018-08-01

2490 Molecular and topological reorganizations in mitochondrial architecture interplay during Bax-mediated steps of apoptosis

Ader, N. R.; Hoffmann, P. C.; Ganeva, I.; Borgeaud, A. C.; Wang, C.; Youle, R. J.; Kukulski, W.

10.1101/382432 — cell biology — Posted on 2018-08-01

2491 A molecular inversion probe and sequencing-based microsatellite instability assay for high throughput cancer diagnostics and Lynch syndrome screening

Gallon, R.; Hayes, C.; Redford, L.; Alhilal, G.; O'Brien, O.; Waltham, A.; Needham, S.; Arends, M.; Oniscu, A.; Alonso, A. M.; Moreno-Laguna, S.; Sheth, H.; Santibanez-Koref, M.; Jackson, M. S.; Burn, J.

10.1101/382754 — cancer biology — Posted on 2018-08-01

2492 A model-based high throughput method for fecundity estimation in fruit fly studies.

Ng'oma, E.; King, E. G.; Middleton, K. M.

10.1101/382804 — bioinformatics — Posted on 2018-08-01

2493 Comparing sequence and structure of falcipains and human homologs at prodomain and catalytic active site for malarial peptide-based inhibitor design

Musyoka, T.; Njuguna, J.; Tastan Bishop, O.

10.1101/381566 — bioinformatics — Posted on 2018-08-01

2494 Skin Lesion Segmentation with Improved C-UNet Networks

Jiang, H.; Rong, R.; Wu, J.; Li, X.; Dong, X.; Chen, E. Z.

10.1101/382549 — bioengineering — Posted on 2018-08-01

2495 Quantitative analysis reveals the basic behavioural repertoire of the urochordate Ciona intestinalis.

Rudolf, J.; Dondorp, D.; Canon, L.; Tieo, S.; Chatzigeorgiou, M.

10.1101/382465 — animal behavior and cognition — Posted on 2018-08-01

2496 A Persistence Detector for Metabolic Network Rewiring in an Animal

Bulcha, J. T.; Giese, G. E.; Ali, M. Z.; Lee, Y.-U.; Walker, M. D.; Holdorf, A. D.; Yilmaz, L. S.; Brewster, R. C.; Walhout, A. J.

10.1101/382507 — systems biology — Posted on 2018-08-01

2497 Thylakoid-integrated recombinant Hcf106 participates in the chloroplast Twin Arginine Transport (cpTat) system

Ma, Q.; Fite, K.; New, C. P.; Dabney-Smith, C.

10.1101/382812 — plant biology — Posted on 2018-08-01

2498 Multifaceted integration - memory for faces is subserved by widespread connections between visual, memory, social and auditory networks

Ramot, M.; Walsh, C.; Martin, A.

10.1101/382739 — neuroscience — Posted on 2018-08-01

2499 The allergic response mediated by fire ant venom proteins

Zamith-Miranda, D.; Fox, E. G. P.; Monteiro, A. P.; Gama, D.; Poublan, L. E.; Araujo, A. F. d.; Araujo, M. F. C.; Atella, G. C.; Machado, E. A.; Diaz, B. L.

10.1101/382697 — immunology — Posted on 2018-08-01

2500 Ancestry-dependent Enrichment of Deleterious Homozygotes in Runs of Homozygosity

Szpiech, Z. A.; Mak, A. C.; White, M. J.; Hu, D.; Eng, C.; Burchard, E. G.; Hernandez, R. D.

10.1101/382721 — genetics — Posted on 2018-08-01

2501 Measuring intolerance to mutation in human genetics

Fuller, Z.; Berg, J. J.; Mostafavi, H.; Sella, G.; Przeworski, M.

10.1101/382481 — genetics — Posted on 2018-08-01

2502 Adaptive phenotypic divergence in teosinte differs across biotic contexts

O'Brien, A. M.; Sawers, R. J. H.; Strauss, S. Y.; Ross-Ibarra, J.

10.1101/382770 — evolutionary biology — Posted on 2018-08-01

2503 Nematode germ granule assembly is linked to mRNA repression

Aoki, S. T.; Crittenden, S. L.; Lynch, T. R.; Bingman, C. A.; Wickens, M.; Kimble, J.

10.1101/382838 — developmental biology — Posted on 2018-08-01

2504 Paleo-oscillomics: inferring aspects of Neanderthal language abilities from gene regulation of neural oscillations

Murphy, E.; Benitez-Burraco, A.

10.1101/167528 — neuroscience — Posted on 2018-08-01

2505 The Object Space Task for mice and rats

Genzel, L.; Schut, E.; Schroeder, T.; Eichler, R.; Gomez, A.; Navarro Lobato, I.; Battaglia, F.

10.1101/198382 — animal behavior and cognition — Posted on 2018-08-01

2506 Lineage specific histories of Mycobacterium tuberculosis dispersal in Africa and Eurasia

O'Neill, M. B.; Shockey, A. C.; Zarley, A.; Aylward, W.; Eldholm, V.; Kitchen, A.; Pepperell, C. S.

10.1101/210161 — evolutionary biology — Posted on 2018-08-01

2507 Rapid adaptation to high temperatures in Chironomus riparius

Foucault, Q.; Wieser, A.; Waldvogel, A.-M.; Feldmeyer, B.; Pfenninger, M.

10.1101/205195 — evolutionary biology — Posted on 2018-08-01

2508 Synthetic metabolic pathways for photobiological conversion of CO2 into hydrocarbon fuel

Yunus, I. S.; Wichmann, J.; Woerdenweber, R.; Lauersen, K. J.; Kruse, O.; Jones, P.

10.1101/381913 — synthetic biology — Posted on 2018-08-01

2509 The ventral visual pathway represents animal appearance over animacy, unlike human behavior and deep neural networks

Bracci, S.; Kalfas, I.; Op de Beeck, H.

10.1101/228932 — neuroscience — Posted on 2018-08-01

2510 No clear evidence for correlations between handgrip strength and sexually dimorphic acoustic properties of voices

Han, C.; Wang, H.; Fasolt, V.; Hahn, A.; Holzleitner, I. J.; Lao, J.; DeBruine, L.; Feinberg, D.; Jones, B.

10.1101/227165 — evolutionary biology — Posted on 2018-08-01

2511 Transcription organizes euchromatin similar to an active microemulsion

Hilbert, L.; Sato, Y.; Kimura, H.; Jülicher, F.; Honigmann, A.; Zaburdaev, V.; Vastenhouw, N.

10.1101/234112 — cell biology — Posted on 2018-08-01

2512 The individual functional connectome is unique and stable over months to years

Horien, C.; Shen, X.; Scheinost, D.; Constable, R. T.

10.1101/238113 — neuroscience — Posted on 2018-08-01

2513 Predicting Evolutionarily Stable Strategies fromFunctional Responses of Sonoran Desert Annuals toPrecipitation

Cuello, W. S.; Gremer, J.; Trimmer, P.; Sih, A.; Schreiber, S.

10.1101/271080 — ecology — Posted on 2018-08-01

2514 Oxygen diffusion in ellipsoidal tumor spheroids

Grimes, D. R.; Currell, F. J.

10.1101/271890 — cancer biology — Posted on 2018-08-01

2515 No evidence of functional co-adaptation between clustered microRNAs

Marco, A.

10.1101/274811 — evolutionary biology — Posted on 2018-08-01

2516 Long-read sequence capture of the hemoglobin gene clusters across species

Hoff, S. N. K.; Baalsrud, H. T.; Tooming-Klunderud, A.; Skage, M.; Richmond, T.; Obernosterer, G.; Shirzadi, R.; Torresen, O. K.; Jakobsen, K. S.; Jentoft, S.

10.1101/297796 — genomics — Posted on 2018-08-01

2517 Comparison of ultracentrifugation and a commercial kit for isolation of exosomes derived from glioblastoma and breast cancer cell lines

Skottvoll, F. S.; Berg, H. E.; Bjorseth, K.; Lund, K.; Roos, N.; Bekhradnia, S.; Thiede, B.; Roberg-Larsen, H.; Nystrom, B.; Lundanes, E.; Wilson, S. R.

10.1101/274910 — biochemistry — Posted on 2018-08-01

2518 Synthetic chromosome fusion: effects on genome structure and function

Luo, J.; Mercy, G.; Vale-Silva, L. A.; Sun, X.; Agmon, N.; Zhang, W.; Yang, K.; Stracquadanio, G.; Thierry, A.; Ahn, J. Y.; Adoff, G.; D'Avino, A.; Berger, H.; Chen, Y.; Chickering, M.; Fishman, O.; Greeno, R. V.; Kim, S.; Kim, S.; Lim, H. S.; Im, J.; Meyer, L.; Moyer, A.; Mullangi, S.; Murphy, N. A.; Natov, P.; Nimer, M.; Radley, A.; Tripathy, A.; Wang, T.; Wilkerson, N.; Zheng, T.; Zhou, V.; Kaback, D. B.; Bader, J. S.; Mitchell, L. A.; Mozziconacci, J.; Hochwagen, A.; Koszul, R.; Boeke, J. D.

10.1101/381137 — synthetic biology — Posted on 2018-08-01

2519 Hippocampal synchrony and neocortical desynchrony cooperate to encode and retrieve episodic memories

Griffiths, B. J.; Michelmann, S.; Roux, F.; Chelvarajah, R.; Rollings, D. T.; Sawlani, V.; Hamer, H.; Gollwitzer, S.; Kreiselmeyer, G.; Staresina, B.; Wimber, M.; Hanslmayr, S.

10.1101/305698 — neuroscience — Posted on 2018-08-01

2520 Binocular modulation of monocular V1 neurons

Dougherty, K.; Cox, M. A.; Westerberg, J.; Maier, A.

10.1101/320218 — neuroscience — Posted on 2018-08-01

2521 How exerting control over outcomes affects the neural coding of tasks and outcomes

Wisniewski, D.; Forstmann, B.; Brass, M.

10.1101/375642 — neuroscience — Posted on 2018-08-01

2522 Extreme Amyloid Polymorphism in Staphylococcus aureus Virulent PSMα Peptides

Salinas, N.; Colletier, J.-P.; Moshe, A.; Landau, M.

10.1101/309062 — biochemistry — Posted on 2018-08-01

2523 KLF4 binding during reprogramming is involved in 3D architectural rewiring and transcriptional regulation of enhancer hubs

Di Giammartino, D. C.; Liu, Y.; Kloetgen, A.; Polyzos, A. P.; Kim, D.; Stadtfeld, M.; Tsirigos, A.; Apostolou, E.

10.1101/382473 — molecular biology — Posted on 2018-08-01

2524 A subfunctionalization epistasis model to evaluate homeologous gene interactions in allopolyploid wheat

Santantonio, N.; Jannink, J.-L.; Sorrells, M.

10.1101/376731 — genetics — Posted on 2018-08-01

2525 Magnetic resonance spectroscopy analysis of intramyocellular lipid composition in lipodystrophic patients and athletes

Savage, D. B.; Watson, L.; Carr, K.; Adams, C.; Brage, S.; Chatterjee, K. K.; Hodson, L.; Boesch, C.; Kemp, G. J.; Sleigh, A.

10.1101/382283 — biochemistry — Posted on 2018-08-01

2526 Spontaneous network activity accounts for variability in stimulus-induced gamma responses

Hirschmann, J.; Baillet, S.; Schnitzler, A.; Woolrich, M.; Vidaurre, D.; Florin, E.

10.1101/381236 — neuroscience — Posted on 2018-08-01

2527 Genome-wide repressive capacity of promoter DNA methylation is revealed through epigenomic manipulation

Korthauer, K.; Irizarry, R. A.

10.1101/381145 — genomics — Posted on 2018-08-01

2528 Functional Genomics Screen with Pooled shRNA Library and Gene Expression Profiling with Extracts of Azadirachta indica Identify Potential Pathways for Therapeutic Targets in Head and Neck Squamous Cell Carcinoma

Krishnan, N. M.; Katoh, H.; Palve, V.; Pareek, M.; Sato, R.; Ishikawa, S.; Panda, B.

10.1101/381749 — genomics — Posted on 2018-08-01

2529 Using machine learning to predict antimicrobial minimum inhibitory concentrations and associated genomic features for nontyphoidal Salmonella

Nguyen, M.; Long, S. W.; McDermott, P. F.; Olsen, R. J.; Olson, R.; Stevens, R. L.; Tyson, G. H.; Zhao, S.; Davis, J. J.

10.1101/380782 — bioinformatics — Posted on 2018-08-01

2530 Application of an Interpretable Classification Model on Early Folding Residues during Protein Folding

Bittrich, S.; Kaden, M.; Leberecht, C.; Kaiser, F.; Villmann, T.; Labudde, D.

10.1101/381483 — bioinformatics — Posted on 2018-08-01

2531 Inhibitory muscarinic acetylcholine receptors enhance aversive olfactory conditioning in adult Drosophila

Bielopolski, N.; Amin, H.; Apostolopoulou, A. A.; Rozenfeld, E.; Lerner, H.; Huetteroth, W.; Lin, A. C.; Parnas, M.

10.1101/382440 — neuroscience — Posted on 2018-08-01

2532 Carbon monoxide, a retrograde messenger generated in post-synaptic mushroom body neurons evokes local dopamine release

Ueno, K.; Morstein, J.; Ofusa, K.; Naganos, S.; Suzuki-Sawano, E.; Minegishi, A.; Kitagishi, H.; Chang, C.; Horiuchi, J.; Saitoe, M.

10.1101/382127 — neuroscience — Posted on 2018-08-01

2533 Dicer-miR-103/107 controls developmental switch of POMC progenitors into NPY neurons and impacts glucose homeostasis

Croizier, S.; Maillard, J.; Bouret, S. G.

10.1101/381921 — neuroscience — Posted on 2018-08-01

2534 The genetic basis of diurnal preference in Drosophila melanogaster

Pegoraro, M.; Flavell, L. M.; Menegazzi, P.; Columbine, P.; Dao, P.; Charlotte Helfrich-Förster, C.; Tauber, E.

10.1101/380733 — evolutionary biology — Posted on 2018-08-01

2535 Machine learning identifies the immunological signature of Juvenile Idiopathic Arthritis

Van Nieuwenhove, E.; Lagou, V.; Van Eyck, L.; Dooley, J.; Bodenhofer, U.; Goris, A.; Humblet-Baron, S.; Wouters, C.; Liston, A.

10.1101/382499 — immunology — Posted on 2018-08-01

2536 How do dopamine neurons resolve a tradeoff between performance and energy?

Song, M. R.; Lee, S. W.

10.1101/381103 — neuroscience — Posted on 2018-08-01

2537 KLF4 binding during reprogramming is involved in 3D architectural rewiring and transcriptional regulation of enhancer hubs

Apostolou, E.; Di Giammartino, D. C.; Liu, Y.; Kloetgen, A.; Polyzos, A. P.; Kim, D.; Stadtfeld, M.; Tsirigos, A.

10.1101/382473 — molecular biology — Posted on 2018-08-01

2538 Niacin fine-tunes energy homeostasis through canonical GPR109A signaling

Zhou, N.; Ye, L.; Cao, Z.; Lai, X.; Wang, W.; Guo, Z.; Yan, L.; Wang, Y.; Shi, Y.

10.1101/382416 — cell biology — Posted on 2018-08-01

2539 Universal cancer tasks, evolutionary tradeoffs, and the functions of driver mutations

Hausser, J.; Szekely, P.; Bar, N.; Zimmer, A.; Sheftel, H.; Caldas, C.; Alon, U.

10.1101/382291 — cancer biology — Posted on 2018-08-01

2540 Mechanism of replication-coupled DNA-protein crosslink proteolysis by SPRTN and the proteasome

Gao, A.; Larsen, N. B.; Sparks, J. L.; Gallina, I.; Mann, M.; Räschle, M.; Walter, J. C.; Duxin, J. P.

10.1101/381889 — molecular biology — Posted on 2018-08-01

2541 Single-cell RNA-seq reveals distinct dynamic behavior of sex chromosomes during early human embryogenesis

Zhou, Q.; Wang, T.; Leng, L.; Zheng, W.; Huang, J.; Fang, F.; Yang, L.; Wang, J.; Yang, H.; Chen, F.; Lin, G.; Wang, W.-J.; Kristiansen, K.

10.1101/382085 — developmental biology — Posted on 2018-08-01

2542 RAB6 and microtubules restrict secretion to focal adhesions

Fourriere, L.; Kasri, A.; Gareil, N.; Bardin, S.; Boulanger, J.; Sikora, R.; Boncompain, G.; Miserey-Lenkei, S.; Perez, F.; Goud, B.

10.1101/382176 — cell biology — Posted on 2018-08-01

2543 Non-invasive spinal electro-magnetic stimulation (SEMS): a tool for evaluation and modulation of lower limb spinal-muscular transmission in healthy adults

Arvanian, V. L.; Petrosyan, H.; Zou, C.; Zaidi, M.; Hou, W.; Tesfa, A.; Fahmy, M.; Kaufman, M. A.; Sisto, S. A.; Leone, C.

10.1101/382341 — neuroscience — Posted on 2018-08-01

2544 Climate Resilience Index as a tool to explore households’ resilience to climate change-induced shocks in Dinki watershed, central highlands of Ethiopia Households’ resilience to climate change impacts

Asmamaw, M.; Ambelu, A.; Mereta, S. T.

10.1101/382358 — scientific communication and education — Posted on 2018-08-01

2545 The role of control region mitochondrial DNA mutations in cardiovascular disease: stroke and myocardial infarction

Umbria, M.; Ramos, A.; Aluja, M. P.; Santos, C.

10.1101/382374 — genetics — Posted on 2018-08-01

2546 Age and genetic background determine hybrid male sterility in house mice

Aylor, D. L.; Widmayer, S. J.

10.1101/382382 — genetics — Posted on 2018-08-01

2547 A standardised framework to identify optimal animal models for efficacy assessment in drug development

S. Ferreira, G.; Veening-Griffioen, D.; Boon, W.; Moors, E.; de Gispen-Wied, C.; Schellekens, H.; van Meer, P.

10.1101/382366 — pharmacology and toxicology — Posted on 2018-08-01

2548 Tuberculosis in the military: Trends in notification and treatment outcomes within the Zimbabwe Defence Force, Dependants and Communities 2010-2015

MURINGAZUVA, C.; CHIMEDZA, J.; MUTETSE, G. N.; DOBBIE, M.; JASPER CHIMEDZA, GODFREY MUTETSE, MUNYARADZI DOBBIE,

10.1101/382325 — epidemiology — Posted on 2018-08-01

2549 Magnitude of road traffic accident related injuries and fatalities in Ethiopia

Abegaz, T.; Gebremedhin, S.

10.1101/382333 — epidemiology — Posted on 2018-08-01

2550 Modified TCA/acetone precipitation of proteins for proteomic analysis

Niu, L.; Zhang, H.; Liu, H.; Wu, X.; Wang, W.

10.1101/382317 — biochemistry — Posted on 2018-08-01

2551 Iso-relevance Functions - A Systematic Approach to Ranking Genomic Features by Differential Effect Size

Nayak, S.; Lahens, N.; Kim, E. J.; Ricciotti, E.; Paschos, G.; Tiskoff, S.; Sarantopoulou, D.; Sengupta, S.; Cooperman, B.; Grosser, T.; Grant, G.

10.1101/381814 — bioinformatics — Posted on 2018-08-01

2552 A malaria transmission model with seasonal mosquito life-history traits

Djidjou-Demasse, R.; Abiodun, G. J.; Adeola, A. M.; Botai, J.

10.1101/377184 — epidemiology — Posted on 2018-08-01

2553 Causal effects of lifetime smoking on risk for depression and schizophrenia: Evidence from a Mendelian randomisation study

Wootton, R. E.; Richmond, R. C.; Stuijfzand, B. G.; Lawn, R. B.; Sallis, H. M.; Taylor, G. M. J.; Jones, H. J.; Zammit, S.; Davey Smith, G.; Munafo, M. R.

10.1101/381301 — epidemiology — Posted on 2018-08-01

2554 Introducing risk inequality metrics in tuberculosis policy development

Gomes, G.; Oliveira, J.; Bertolde, A.; Nguyen, T. A.; Maciel, E.; Duarte, R.; Nguyen, B. H.; Shete, P.; Lienhardt, C.

10.1101/380865 — epidemiology — Posted on 2018-08-01

2555 Isoform switching as a mechanism of acquired resistance to isocitrate dehydrogenase inhibition

Harding, J. J.; Lowery, M. A.; Shih, A. H.; Schvartzman, J. M.; Hou, S.; Famulare, C.; Patel, M.; Roshal, M.; Do, R. K. G.; Zehir, A.; You, D.; Selcuklu, S. D.; Viale, A.; Tallman, M. S.; Hyman, D. M.; Reznik, E.; Finley, L. W. S.; Papaemmanuil, E.; Tosolini, A.; Frattini, M. G.; MacBeth, K. J.; Liu, G.; Fan, B.; Choe, S.; Wu, B.; Janjigian, Y. Y.; Mellinghoff, I. K.; Diaz, L. A.; Levine, R. L.; Abou-Alfa, G. K.; Stein, E. M.; Intlekofer, A. M.

10.1101/381954 — cancer biology — Posted on 2018-08-01

Archive, 2018-08