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Archive, 2021-09

5 Progranulin deficiency results in reduced bis(monoacylglycero)phosphate (BMP) levels and gangliosidosis
Boland, S.; Swarup, S.; Ambaw, Y. A.; Richards, R. C.; Fischer, A. W.; Singh, S.; Aggarwal, G.; Spina, S.; Nana, A. L.; Grinberg, L. T.; Seeley, W. W.; Surma, M. A.; Klose, C.; Paulo, J. A.; Nguyen, A. D.; Harper, J. W.; Walther, T. C.; Farese, R. V.
10.1101/2021.09.30.461806 — cell biology — Posted on 2021-09-30
7 A standardized method to purify cardiomyocytes from individual mouse hearts of any age
Nicks, A. M.; Holman, S. R.; Chan, A. Y.; Tsang, M.; Young, P. E.; Humphreys, D. T.; Naqvi, N.; Husain, A.; Li, M.; Smith, N. J.; Iismaa, S. E.; Graham, R. M.
10.1101/2021.09.30.462562 — cell biology — Posted on 2021-09-30
9 Sensory evidence accumulation using optic flow in a naturalistic navigation task
Alefantis, P.; Lakshminarasimhan, K. J.; Avilla, E.; Noel, J.-P.; Pitkow, X.; Angelaki, D.
10.1101/2021.04.26.441532 — neuroscience — Posted on 2021-09-30
17 Association between Cognitive Function and Large Optic Nerve Cupping, Accounting for Cup-Disc-Ratio Genetic Risk Score
Hallak, J.; Kravets, S.; Rupnow, R. A.; Sethi, A.; Espeland, M.; Louis, P. R.; Rapp, S.; Klein, B.; Meuer, S.; Haan, M.; Maki, P.; Vajaranant, T.
10.1101/2021.09.30.462651 — genetics — Posted on 2021-09-30
18 Variation in the response to malaria in Diversity Outbred mice
Gupta, A. S.; Chevee, V.; Kirosingh, A. S.; Davis, N. M.; Schneider, D. S.
10.1101/2021.09.29.462483 — microbiology — Posted on 2021-09-30
19 A gut commensal niche regulates stable association of a multispecies microbiota
Dodge, R.; Jones, E. W.; Zhu, H.; Obadia, B.; Martinez, D. J.; Wang, C.; Aranda-Diaz, A.; Aumiller, K.; Liu, Z.; Voltolini, M.; Brodie, E. L.; Huang, K. C.; Carlson, J. M.; Sivak, D. A.; Spradling, A. C.; Ludington, W. B.
10.1101/2021.09.30.462663 — microbiology — Posted on 2021-09-30
23 Structure and function of N-acetylglucosamine kinase illuminates the catalytic mechanism of ROK kinases
Roy, S.; Vega, M. V.; Ames, J. R.; Britten, N.; Evans, K.; Kent, A.; Isupov, M. N.; Harmer, N.
10.1101/2021.09.30.462564 — biochemistry — Posted on 2021-09-30
29 Efficient single copy integration via homology-directed repair (scHDR) by 5'modification of large DNA donor fragments in mice
Medert, R.; Thumberger, T.; Tavhelidse, T.; Hub, T.; Kellner, T.; Ogushi, Y.; Dlugosz, S.; Zimmermann, F.; Wittbrodt, J.; Freichel, M.
10.1101/2021.09.30.462539 — molecular biology — Posted on 2021-09-30
31 Transition of Vibrio cholerae through a natural host induces resistance to environmental changes
Depelteau, J. S.; Limpens, R.; Nag, D.; Koch, B. E. V.; Withey, J. H.; Meijer, A. H.; Briegel, A.
10.1101/2021.09.30.462513 — microbiology — Posted on 2021-09-30
32 Neuro-computational mechanisms of action-outcome learning under moral conflict
Fornari, L.; Ioumpa, K.; Nostro, A.; Evans, N. J.; De Angelis, L.; Paracampo, R.; Gallo, S.; Spezio, M.; Keysers, C.; Gazzola, V.
10.1101/2020.06.10.143891 — neuroscience — Posted on 2021-09-30
35 Light chain 2 is a Tctex-type related axonemal dynein light chain that regulates directional ciliary motility in Trypanosoma brucei
Godar, S.; Oristian, J.; Hinsch, V.; Wentworth, K.; Lopez, E.; Amlashi, P.; Enverso, G.; Markley, S.; Alper, J. D.
10.1101/2021.09.29.462335 — biophysics — Posted on 2021-09-30
36 Structures of core eukaryotic protein complexes
Humphreys, I. R.; Pei, J.; Baek, M.; Krishnakumar, A.; Anishchenko, I.; Ovchinnikov, S. R.; Zheng, J.; Ness, T.; Banjade, S.; Bagde, S. R.; Stancheva, V.; Li, X.; Liu, K.; Zheng, Z.; Barerro, D.; Roy, U.; Fernandez, I. S.; Szakal, B.; Branzei, D.; Greene, E. C.; Biggins, S.; Keeney, S.; Miller, E. A.; Fromme, J. C.; Hendrickson, T.; Cong, Q.; Baker, D.
10.1101/2021.09.30.462231 — biochemistry — Posted on 2021-09-30
37 PEPATAC: An optimized pipeline for ATAC-seq data analysis with serial alignments
Smith, J. P.; Corces, M. R.; Xu, J.; Reuter, V. P.; Chang, H. Y.; Sheffield, N. C.
10.1101/2020.10.21.347054 — genomics — Posted on 2021-09-30
39 Reovirus infection is regulated by NPC1 and endosomal cholesterol homeostasis
Ortega Gonzalez, P.; Taylor, G. M.; Jangra, R.; Tenorio Vela, R.; Fernandez de Castro Martin, I.; Mainou, B.; Orchard, R.; Wilen, C. B.; Brigleb, P. H.; Sojati, J.; Chandran, K.; Risco, C.; Dermody, T. S.
10.1101/2021.09.27.462002 — cell biology — Posted on 2021-09-30
40 Bromodomain factor 5 is an essential transcriptional regulator of the Leishmania genome.
Jones, N. G.; Geoghegan, V.; Moore, G.; Carnielli, J. B. T.; Newling, K.; Calderon, F.; Gabarro, R.; Martin, J.; Prinjha, R.; Rioja, I.; Wilkinson, A. J.; Mottram, J. C.
10.1101/2021.09.29.462384 — cell biology — Posted on 2021-09-30
41 Prime Editing Efficiency and Fidelity are Enhanced in the Absence of Mismatch Repair
Ferreira da Silva, J.; Oliveira, G.; Arasa-Verge, E.; Moretton, A.; Thimelthaler, G.; Jiricny, J.; Loizou, J. I.
10.1101/2021.09.30.462548 — molecular biology — Posted on 2021-09-30
43 Drivers and Determinants of Strain Dynamics Following Faecal Microbiota Transplantation
Schmidt, T. S.; Li, S. S.; Maistrenko, O. M.; Akkani, W.; Coelho, L. P.; Dolai, S.; Fullam, A.; Glazek, A.; Hercog, R.; Herrema, H.; Jung, F.; Kandels, S.; Orakov, A.; Van Rossum, T.; Benes, V.; Borody, T. J.; de Vos, W. M.; Ponsioen, C. Y.; Nieuwdorp, M.; Bork, P.
10.1101/2021.09.30.462010 — microbiology — Posted on 2021-09-30
45 The unforeseen intracellular lifestyle of Enterococcus faecalis in hepatocytes
Nunez, N.; Derre-Bobillot, A.; Lakisic, G.; Lecomte, A.; Mercier-Nome, F.; Cassard, A.-M.; Bierne, H.; SERROR, P.; ARCHAMBAUD, C.
10.1101/2021.09.30.462169 — microbiology — Posted on 2021-09-30
46 A model screening pipeline for bile acid converting anti-Clostridioides difficile bacteria reveals unique biotherapeutic potential of Peptacetobacter hiranonis
A. Vinithakumari, A.; Hernandez, B. G.; Ghimire, S.; Adams, S.; Stokes, C.; Jepsen, I.; Brezina, C.; Sahin, O.; Li, G.; Tangudu, C.; Andreasen, C.; Phillips, G. J.; Wannemuehler, M.; Jergens, A. E.; Scaria, J.; Sponseller, B.; Mooyottu, S.
10.1101/2021.09.29.462466 — microbiology — Posted on 2021-09-30
49 Ad26.COV2.S Prevents SARS-CoV-2 Induced Pathways of Inflammation and Thrombosis in Hamsters
Aid, M.; Vidal, S.; Piedra-Mora, C.; Ducat, S.; Chan, C.; Bondoc, S.; Colarusse, A.; Starke, C.; Nekorchuk, M.; Busman-Sahay, K.; Estes, J.; Martinot, A.; Barouch, D. H.
10.1101/2021.09.30.462514 — microbiology — Posted on 2021-09-30
50 SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies
Reincke, S. M.; Yuan, M.; Kornau, H.-C.; Corman, V. M.; van Hoof, S.; Sanchez-Sendin, E.; Ramberger, M.; Yu, W.; Hua, Y.; Tien, H.; Schmidt, M. L.; Schwarz, T.; Jeworowski, L. M.; Brandl, S. E.; Foverskov Rasmussen, H.; Homeyer, M. A.; Stöffler, L.; Barner, M.; Kunkel, D.; Huo, S.; Horler, J.; Wardenburg, N. v.; Kroidl, I.; Eser, T. M.; Wieser, A.; Geldmacher, C.; Hoelscher, M.; Gänzer, H.; Weiss, G.; Schmitz, D.; Drosten, C.; Prüss, H.; Wilson, I. A.; Kreye, J.
10.1101/2021.09.30.462420 — immunology — Posted on 2021-09-30
52 Durability of immune responses to the BNT162b2 mRNA vaccine
Suthar, M.; S Arunachalam, P.; Hu, M.; Reis, N.; Trisal, M.; Raeber, O.; Chinthrajah, S.; Davis-Gardner, M. E.; Manning, K.; Mudvari, P.; Godbole, S.; Boritz, E.; Henry, A. R.; Douek, D.; Nadeau, K.; Kawaoka, Y.; Zarnitsyna, V. I.; Pulendran, B.; Halfmann, P.
10.1101/2021.09.30.462488 — immunology — Posted on 2021-09-30
53 Pyronaridine Protects Against SARS-CoV-2 in Mouse
Puhl, A. C.; Gomes, G. F.; Damasceno, S.; de Godoy, A. S.; Noske, G. D.; Nakamura, A. M.; Gawrijuk, V. O.; Fernandes, R. S.; Monakhova, N.; Riabova, O.; Lane, T. R.; Makarov, V.; Veras, F. P.; Batah, S. S.; Fabro, A. T.; Oliva, G.; Cunha, F.; Alves-Filho, J. C.; Cunha, T. M.; Ekins, S.
10.1101/2021.09.30.462449 — pharmacology and toxicology — Posted on 2021-09-30
58 Accelerating Identification of Chromatin Accessibility from noisy ATAC-seq Data using Modern CPUs
Chaudhary, N.; Misra, S.; Kalamkar, D.; Heinecke, A.; Georganas, E.; Ziv, B.; Adelman, M.; Kaul, B.
10.1101/2021.09.28.462099 — genomics — Posted on 2021-09-30
65 Numb reduces Tau levels and prevents neurodegeneration in mouse models of tauopathy in an isoform-specific manner
Lacomme, M.; Hales, S. C.; Stevanovic, K.; Jolicoeur, C.; Bois, T.; Cai, J.; Desrosiers, M.; Dalkara, D.; Cayouette, M.
10.1101/2021.09.28.462203 — neuroscience — Posted on 2021-09-30
68 Biomass formation and sugar release efficiency of Populus modified by altered expression of a NAC transcription factor
Payyavula, R. S.; Badmi, R.; Jawdy, S. S.; Rodriguez, M.; Gunter, L.; Sykes, R. W.; Winkeler, K. A.; Collins, C. M.; Rottmann, W. H.; Chen, J.-G.; Yang, X.; Tuskan, G. A.; Kalluri, U. C.
10.1101/2021.09.28.462238 — plant biology — Posted on 2021-09-30
69 Dynamics of deep water and N uptake under varied N and water supply
Chen, G.; Rasmussen, C. R.; Dresboell, D. B.; Smith, A. G.; Thorup-Kristensen, K.
10.1101/2021.09.27.461951 — plant biology — Posted on 2021-09-30
70 A NET4-RabG3 couple mediate the link between actin and the tonoplast and is essential for normal actin cytoskeletal remodelling in stomatal closure to flg22
HAWKINS, T. J.; Kopischke, M.; Mentlak, D.; Duckney, P.; Kroon, J.; Bui, M. T.; Richardson, C.; Casey, M.; Alexander, A.; De Jaeger, G.; Kalde, M.; Moore, I.; Dagdas, Y.; Hussey, P. J.; Robatzek, S.
10.1101/2021.09.29.461190 — plant biology — Posted on 2021-09-30
75 Fast Optoacoustic Mesoscopy of Microvascular Endothelial Dysfunction in Cardiovascular Risk and Disease
He, H.; Karlas, A.; Fasoula, N.-A.; Kallmayer, M.; Aguirre, J.; Eckstein, H.-H.; Ntziachristos, V.
10.1101/2021.09.28.462150 — bioengineering — Posted on 2021-09-30
78 Repression of the Hox gene abd-A by ELAV-mediated Transcriptional Interference
Castro Alvarez, J. J.; Revel, M.; Cleard, F.; Pauli, D.; Karch, F.; Maeda, R. K.
10.1101/2021.09.29.462302 — genetics — Posted on 2021-09-30
79 Differential use of multiple genetic sex determination systems in divergent ecomorphs of an African crater lake cichlid
Munby, H.; Linderoth, T.; Fischer, B.; Du, M.; Vernaz, G.; Tyers, A. M.; Ngatunga, B. P.; Shechonge, A.; Denise, H.; McCarthy, S. A.; Bista, I.; Miska, E. A.; Santos, M. E.; Genner, M. J.; Turner, G. F.; Durbin, R.
10.1101/2021.08.05.455235 — evolutionary biology — Posted on 2021-09-30
81 Neurofibromin 1 controls metabolic balance and Notch-dependent quiescence of juvenile myogenic progenitors
Wei, X.; Lienhard, M.; Murgai, A.; Franke, J.; Poehle-Kronawitter, S.; Kotsaris, G.; Wu, H.; Boerno, S.; Timmermann, B.; Glauben, R.; Stricker, S.
10.1101/2021.09.28.462168 — cell biology — Posted on 2021-09-30
84 Enhanced nociception in a rabbit model of cerebral palsy
Reedich, E. J.; Genry, L. T.; Cavarsan, C. F.; Mena Avila, E.; Singer, M. A.; Boudreau, D. M.; Brennan, M. C.; Garrett, A. M.; Dowaliby, L.; Detloff, M. R.; Quinlan, K. A.
10.1101/2021.09.28.462176 — neuroscience — Posted on 2021-09-30
90 All2: A tool for selecting mosaic mutations from comprehensive multi-cell comparisons
SARANGI, V.; Jang, Y.; Suvakov, M.; Bae, T.; Fasching, L.; Sekar, S.; Tomasini, L.; Mariani, J.; Vaccarino, F. M.; Abyzov, A.
10.1101/2021.09.29.462281 — bioinformatics — Posted on 2021-09-30
94 The use of barcoded Asaia bacteria in mosquito in vivo screens for identification of systemic insecticides and inhibitors of malaria transmission
Angelika, S.; Vos, M.; Henderson, R.; Eldering, M.; Koolen, K.; Sheshachalam, A.; Favia, G.; Samby, K.; Herreros, E.; Dechering, K. J.
10.1101/2021.09.29.462277 — bioengineering — Posted on 2021-09-30
95 Transient late gestation prenatal hypoxic insult results in functional deficits but not gross neuroanatomic deficits in mice
Cristancho, A. G.; Gadra, E. C.; Samba, I. M.; Zhao, C.; Ouyang, M.; Magnitsky, S.; Huang, H.; Viaene, A. N.; Anderson, S. A.; Marsh, E. D.
10.1101/2021.08.04.451528 — animal behavior and cognition — Posted on 2021-09-30
96 Benchmarking challenging small variants with linked and long reads
Wagner, J.; Olson, N. D.; Harris, L.; Khan, Z.; Farek, J.; Mahmoud, M.; Stankovic, A.; Kovacevic, V.; Wenger, A. M.; Rowell, W. J.; Xiao, C.; Yoo, B.; Miller, N.; Rosenfeld, J. A.; Ni, B.; Zarate, S.; Kirsche, M.; Aganezov, S.; Schatz, M.; Narzisi, G.; Byrska-Bishop, M.; Clarke, W.; Evani, U. S.; Markello, C.; Shafin, K.; Zhou, X.; Sidow, A.; Bansal, V.; Ebert, P.; Marschall, T.; Lansdorp, P.; Hanlon, V.; Mattsson, C.-A.; Martinez Barrio, A.; Fiddes, I. T.; Fungtammasan, A.; Chin, C.-S.; Sedlazeck, F. J.; Carroll, A.; Salit, M.; Zook, J. M.; Genome in a Bottle Consortium,
10.1101/2020.07.24.212712 — genomics — Posted on 2021-09-30
97 Investigating the genetic architecture of eye colour in a Canadian cohort
Lona-Durazo, F.; Thakur, R.; Pairo-Castineira, E.; Funderburk, K.; Zhang, T.; Kovacs, M. A.; Choi, J.; Jackson, I. J.; Brown, K. M.; Parra, E. J.
10.1101/2021.09.29.462299 — genetics — Posted on 2021-09-30
98 A genetic switch for male UV-iridescence in an incipient species pair of sulphur butterflies
Ficarrotta, V.; Hanly, J. J.; Loh, L. S.; Francescutti, C. M.; Ren, A.; Tunström, K.; Wheat, C. W.; Porter, A. H.; Counterman, B. A.; Martin, A.
10.1101/2021.05.21.445125 — evolutionary biology — Posted on 2021-09-30
103 Birth and delineation of the intestinal stem cell niche
McCarthy, N.; Tie, G.; Madha, S.; Maglieri, A.; Kraiczy, J.; Shivdasani, R.
10.1101/2021.09.28.462142 — developmental biology — Posted on 2021-09-30
110 Enhanced Production of Mesencephalic Dopaminergic Neurons from Lineage-Restricted Human Undifferentiated Stem Cells
Maimaitili, M.; Chen, M.; Febbraro, F.; Mermet-Joret, N.; Lauritsen, J.; Ucuncu, E.; Klaestrup, I. H.; Qvist, P.; Nabavi, S.; Romero-Ramos, M.; Denham, M.
10.1101/2021.09.28.462222 — neuroscience — Posted on 2021-09-30
111 Light-regulated SIK1 remodels the synaptic phosphoproteome to induce sleep
Taylor, L.; Palumaa, T.; Reardon, P. K.; Walsh, S.; Johnson, B.; Liberatori, S.; Hasan, S.; Clark, K.; Mohammed, S.; Cohen, P.; Peirson, S.; Vasudevan, S.; Vyazovskiy, V. V.; Foster, R. G.; Jagannath, A.
10.1101/2021.09.28.462159 — neuroscience — Posted on 2021-09-30
119 A yeast with muscle does not run faster: full humanization of the glycolytic pathway in Saccharomyces cerevisiae
Boonekamp, F.; Knibbe, E.; Vieira Lara, M.; Wijsman, M.; Luttik, M.; van Eunen, K.; den Ridder, M.; Bron, R.; Almonacid Suarez, A. M.; van Rijn, P.; Wolters, J.; Pabst, M.; Daran, J.-M. G.; Bakker, B.; Daran-Lapujade, P.
10.1101/2021.09.28.462164 — systems biology — Posted on 2021-09-30
120 Biotechnology data analysis training with Jupyter Notebooks
Liebal, U. W.; Schimassek, R.; Broderius, I.; Maassen, N.; Vogelgesang, A.; Weyers, P.; Blank, L. M.
10.1101/2021.09.28.462133 — scientific communication and education — Posted on 2021-09-30
121 Robust W1282X-CFTR rescue by a small molecule GSPT1 degrader
Lee, R. E.; Lewis, C. A.; He, L.; Gallant, S. C.; Mascenik, T. M.; Dang, H.; Morton, L. C.; Minges, J. T.; Theile, J. W.; Castle, N. A.; Knowles, M. R.; Kimple, A. J.; Randell, S. H.
10.1101/2021.09.28.462149 — pathology — Posted on 2021-09-30
133 Nanocrown electrodes for robust and scalable intracellular recordings of cardiomyocytes for cardiotoxicity screening
Jahed, Z.; Yang, Y.; Tsai, C.-T.; Foster, E. P.; McGuire, A. F.; Yang, H.; Liu, A.; Forro, C.; Yan, Z.; Ke, X. J.; Zhao, M.-T.; Zheng, W.; Li, X.; Li, T.; Pawlosky, A.; Wu, J. C.; Cui, B.
10.1101/2021.09.28.462181 — bioengineering — Posted on 2021-09-30
134 Metrics of High Cofluctuation and Entropy to Describe Control of Cardiac Function in the Stellate Ganglion
Gurel, N. Z.; Sudarshan, K. B.; Hadaya, J.; Karavos, A.; Temma, T.; Hori, Y.; Armour, A. J.; Kember, G.; Ajijola, O. A.
10.1101/2021.09.28.462183 — bioengineering — Posted on 2021-09-30
136 Enhanced keratin extraction from wool waste using a deep eutectic solvent
Okoro, O.; Jafari, H.; Hobbi, P.; Lei, N.; Alimoradi, H.; Shavandi, A.
10.1101/2021.09.29.462276 — bioengineering — Posted on 2021-09-30
139 Clonal hematopoiesis is associated with increased toxicity in large B-cell lymphoma patients treated with chimeric antigen receptor T cell therapy
Saini, N.; Swoboda, D. M.; Greenbaum, U.; Ma, J.; Patel, R.; Devashish, K.; Strati, P.; Nair, R.; Fayad, L. E.; Ahmed, S.; Lee, H. J.; Iyer, S.; Steiner, R.; Jain, N.; Nastoupil, L.; Jain, P.; Wang, M.; Westin, J.; Green, M. R.; Sallman, D.; Padron, E.; Davila, M.; Locke, F.; Champlin, R.; Shpall, E.; Kebriaei, P.; Flowers, C. R.; Jain, M.; Wang, F.; Futreal, A.; Gillis, N.; Neelapu, S.; Takahashi, K.
10.1101/2021.09.28.461858 — genetics — Posted on 2021-09-30
140 Rod-genesis driven by mafba in an nrl knockout zebrafish model with altered photoreceptor compositions and progressive retinal degeneration
Liu, F.; Qin, Y.; Huang, Y.; Gao, P.; Li, J.; Yu, S.; Jia, D.; Chen, X.; Lv, Y.; Tu, J.; Sun, K.; Han, Y.; Reilly, J.; Shu, X.; Lu, Q.; Tang, Z.; Xu, C.; Luo, D.; Liu, M.
10.1101/2021.09.29.462301 — genetics — Posted on 2021-09-30
141 Improved Characterization of Balancing Selection Genome Wide and a Detailed Look at HLA Genes
Hayeck, T. J.; Mosbruger, T. L.; Bradfield, J. P.; Gleason, A. G.; Damianos, G.; Duke, J. L.; Conlin, L. K.; Turner, T. N.; Sarmady, M.; Monos, D. S.
10.1101/2021.09.28.462165 — genetics — Posted on 2021-09-30
147 Pathogenic mutations in the chromokinesin KIF22 disrupt anaphase chromosome segregation
Thompson, A. F.; Blackburn, P. R.; Babovic-Vuksanovic, D.; Lian, J. B.; Klee, E. W.; Stumpff, J.
10.1101/2021.09.29.462402 — cell biology — Posted on 2021-09-30
148 Peripheral kappa opioid receptor activation drives cold hypersensitivity in mice
Madasu, M. K.; Thang, L. V.; Chilukuri, P.; Palanisamy, S.; Arackal, J. S.; Sheahan, T. D.; Foshage, A. M.; Houghten, R. A.; McLaughlin, J. P.; McCall, J. G.; Al-Hasani, R.
10.1101/2020.10.04.325118 — neuroscience — Posted on 2021-09-30
150 Redundant functions of the SLC5A transporters Rumpel Kumpel and Bumpel in ensheathing glial cells
Yildirim, K.; Winkler, B.; Pogodalla, N.; Mackensen, S.; Baldenius, M.; Garcia, L.; Naffin, E.; Rodrigues, S.; Klambt, C.
10.1101/2021.09.28.462185 — neuroscience — Posted on 2021-09-30
152 Insights into opium poppy (Papaver spp.) genetic diversity from genotyping-by-sequencing analysis
Hong, U. V. T.; Tamiru-Oli, M.; Hurgobin, B.; Okey, C. R.; Abreu, A. R.; Lewsey, M. G.
10.1101/2021.09.28.462245 — plant biology — Posted on 2021-09-30
154 Reference genomes of 545 silkworms enable high-throughput exploring genotype-phenotype relationships
Tong, X.; Han, M.-j.; Lu, K.; Tai, S.; Liang, S.; Liu, Y.; Hu, H.; Shen, J.; Long, A.; Zhan, C.; Ding, X.; Gao, Q.; Zhang, B.; Tan, D.; Yuan, Y.; Guo, N.; Li, Y.; Wu, Z.; Liu, L.; Li, C.; Lu, Y.; Gai, T.; Zhang, Y.; Yang, R.; Qian, H.; Liu, Y.; Luo, J.; Zheng, L.; Lou, J.; Peng, Y.; Zuo, W.; Song, J.; He, S.; Wu, S.; Zou, Y.; Zhou, L.; Zhou, L.; Cheng, L.; Tang, Y.; Cheng, G.; Yuan, L.; He, W.; Xu, J.; Fu, T.; Xiao, Y.; Lei, T.; Xu, A.; Yin, Y.; Wang, J.; Monteiro, A.; Westhof, E.; Lu, C.; Tian, Z.; Wang, W.; Xiang, Z.; Dai, F.
10.1101/2021.09.28.462073 — genomics — Posted on 2021-09-30
156 Chromosome-scale genome assembly of the brown anole (Anolis sagrei), a model species for evolution and ecology
Geneva, A. J.; Park, S.; Bock, D.; de Mello, P.; Sarigol, F.; Tollis, M.; Donihue, C.; Reynolds, R. G.; Feiner, N.; Rasys, A.; Lauderdale, J.; Minchey, S. G.; Alcala, A. J.; Infante, C.; Kolbe, J. J.; Schluter, D.; Menke, D. B.; Losos, J. B.
10.1101/2021.09.28.462146 — genomics — Posted on 2021-09-30
157 Comparative transcriptomic analysis of maize ear heterosis during the inflorescence meristem differentiation stage
Shi, X.; Li, W.; Guo, Z.; Wu, M.; Zhang, X.; Yuan, L.; Qiu, X.; Xing, Y.; Sun, X.; Xie, H.; Tang, J.
10.1101/2021.09.28.462161 — genetics — Posted on 2021-09-30
160 Single-cell transcriptomic analysis unveils spinal motor neuron subtype diversity underpinning the water-to-land transition in vertebrates
Liau, E. S.; Jin, S.; Chen, Y.-C.; Liu, W.-S.; Yong, L. W.; Tsai, C.-T.; Calon, M.; Yu, J.-K.; Su, Y.-H.; Nedelec, S.; Nie, Q.; Chen, J.-A.
10.1101/2021.09.29.462340 — developmental biology — Posted on 2021-09-30
162 Single-nucleus transcriptomic atlas of spinal cord neuron in human
Zhang, D.; Wei, Y.; Liu, J.; Chen, H.; Li, J.; Zhu, T.; Zhou, C.
10.1101/2021.09.28.462103 — neuroscience — Posted on 2021-09-30
164 Hexapeptides from mammalian inhibitory hormone hunt activate and inactivate nematode reproduction
Hart, J. E.; Mohan, S.; Davies, K. G.; Ferneyhough, B.; Clarke, I. J.; Hunt, J. A.; Shnyder, S. D.; Mundy, C. R.; Copsey, D. B.; Howlett, D. R.; Newton, R. P.
10.1101/2021.09.28.462091 — physiology — Posted on 2021-09-30
165 Neuronal glucose metabolism sets cholinergic tone and controls thermo-regulated signaling at the neuromuscular junction
Tang, Y.; Zong, H.; Kwon, H.; Qiu, Y.; Pessin, J. B.; Wu, L.; Buddo, K. A.; Boykov, I.; Schmidt, C.; Lin, C.-T.; Neufer, P. D.; Schwartz, G. J.; Kurland, I. J.; Pessin, J. E.
10.1101/2021.09.28.462124 — cell biology — Posted on 2021-09-30
168 DNA dynamics dictates p53 functional outcome
Safieh, J.; Chazan, A.; Vyas, P.; Saleem, H.; Danin-Poleg, Y.; Ron, D.; Haran, T. E.
10.1101/2021.09.18.460898 — biochemistry — Posted on 2021-09-30
171 The dual function monoclonal antibodies VIR-7831 and VIR-7832 demonstrate potent in vitro and in vivo activity against SARS-CoV-2
Cathcart, A. L.; Havenar-Daughton, C.; Lempp, F. A.; Ma, D.; Schmid, M.; Agostini, M. L.; Guarino, B.; Di iulio, J.; Rosen, L.; Tucker, H.; Dillen, J.; Subramanian, S.; Sloan, B.; Bianchi, S.; Wojcechowskyj, J.; Zhou, J.; Kaiser, H.; Chase, A.; Lauron, E.; Montiel-Ruiz, M.; Spreafico, R.; Noack, J.; Czudnochowski, N.; Sahakyan, A.; Pinto, D.; Saliba, C.; Delotta, E.; Park, A.; Cameroni, E.; Ledoux, S.; Werts, A.; Colas, C.; Soriaga, L.; Telenti, A.; Purcell, L. A.; Hwang, S.; Snell, G.; Virgin, H. W.; Corti, D.; Hebner, C. M.
10.1101/2021.03.09.434607 — immunology — Posted on 2021-09-30
177 STING mediates immune responses in the closest living relatives of animals
Woznica, A.; Kumar, A.; Sturge, C. R.; Xing, C.; King, N.; Pfeiffer, J. K.
10.1101/2021.05.13.443778 — microbiology — Posted on 2021-09-30
178 EEG-based visual deviance detection in freely behaving mice
Kat, R.; van den Berg, B.; Perenboom, M. J. L.; Schenke, M.; van den Maagdenberg, A. M. J. M.; Bruining, H.; Tolner, E. A.; Kas, M. J. H.
10.1101/2021.06.14.448331 — neuroscience — Posted on 2021-09-30
179 Correlation of mitochondrial TOM core complex stop-and-go and open-closed channel dynamics
Wang, S.; Findeisen, L.; Leptihn, S.; Wallace, M. I.; Hörning, M.; Nussberger, S.
10.1101/2021.09.28.462098 — biophysics — Posted on 2021-09-30
180 Functional and Highly Crosslinkable HIV-1 Envelope Glycoproteins Enriched in a Pretriggered Conformation
Nguyen, H. T.; Qualizza, A.; Anang, S.; Zhao, M.; Zou, S.; Zhou, R.; Wang, Q.; Zhang, S.; Deshpande, A. A.; Ding, H.; Smith, A. B.; Kappes, J. C.; Sodroski, J. G.
10.1101/2021.09.27.462085 — molecular biology — Posted on 2021-09-30
182 Small intestine lactobacilli growth promotion and immunomodulation in weaner pigs fed Cyberlindnera jadinii yeast high inclusion diet and exposed to enterotoxigenic Escherichia coli F4+: O149
Iakhno, S.; Hellestveit, S. S.; Umu, O. C. O.; Bogevik, L. T.; Akesson, C. P.; Göksu, A. B.; Press, C. M.; Mydland, L. T.; Overland, M.; Sorum, H.
10.1101/2021.02.11.430732 — microbiology — Posted on 2021-09-30
183 LADON, a natural antisense transcript of NODAL, promotes an invasive behaviour in melanoma cells.
Dutriaux, A.; Diazzi, S.; Caburet, S.; Bresesti, C.; Hardouin, S.; Deshayes, F.; Collignon, J.; Flagiello, D.
10.1101/2020.04.09.032375 — cancer biology — Posted on 2021-09-30
184 Population genomics of Bacillus anthracis from an anthrax hyperendemic area reveals transmission processes across spatial scales and unexpected within-host diversity
Forde, T. L.; Dennis, T. P. W.; Aminu, O. R.; Harvey, W. T.; Hassim, A.; Kiwelu, I.; Medvecky, M.; Mshanga, D.; van Heerden, H.; Vogel, A.; Zadoks, R. N.; Mmbaga, B. T.; Lembo, T.; Biek, R.
10.1101/2021.09.07.459365 — genomics — Posted on 2021-09-30
185 PCSK9 affects expression of key surface proteins in human pancreatic beta cells through intra- and extracellular regulatory circuits
Saitoski, K.; Ryaboshapkina, M.; Hamza, G.; Jarnuczak, A. F.; Berthault, C.; Carlotti, F.; Armanet, M.; Sengupta, K.; Rye Underwood, C.; Andersson, S.; Guillas, I.; Le Goff, W.; Scharfmann, R.
10.1101/2021.09.28.461975 — cell biology — Posted on 2021-09-30
187 Thinking ahead: prediction in context as a keystone of language in humans and machines
Goldstein, A.; Zada, Z.; Buchnik, E.; Schain, M.; Price, A.; Aubrey, B.; Nastase, S. A.; Feder, A.; Emanuel, D.; Cohen, A.; Jansen, A.; Gazula, H.; Choe, G.; Rao, A.; Kim, C.; Casto, C.; Lora, F.; Flinker, A.; Devore, S.; Doyle, W.; Dugan, P.; Friedman, D.; Hassidim, A.; Brenner, M.; Matias, Y.; Norman, K. A.; Devinsky, O.; Hasson, U.
10.1101/2020.12.02.403477 — neuroscience — Posted on 2021-09-30
190 Modeling features of addiction with an oral oxycodone self-administration paradigm
Murphy, C.; Chang, Y.-H.; Pareta, R.; Li, J.-N.; Slivicki, R. A.; Earnest, T.; Tooley, J. R.; Abiraman, K.; Vachez, Y. M.; Gereau, R.; Copits, B. A.; Kravitz, A. V.; Creed, M. C.
10.1101/2021.02.08.430180 — neuroscience — Posted on 2021-09-29
198 Sound level context modulates neural activity in the human brainstem
Herrmann, B.; Yasmin, S.; Araz, K.; Purcell, D. W.; Johnsrude, I. S.
10.1101/2021.06.24.449846 — neuroscience — Posted on 2021-09-29
203 Mixed Effects Machine Learning Models for Colon Cancer Metastasis Prediction using Spatially Localized Immuno-Oncology Markers
Levy, J.; Bobak, C.; Nasir-Moin, M.; Veziroglu, E. M.; Palisoul, S. M.; Barney, R. E.; Salas, L. A.; Christensen, B. C.; Tsongalis, G. J.; Vaickus, L. J.
10.1101/2021.08.01.454649 — pathology — Posted on 2021-09-29
205 Analysis of Normal Levels of Urine and Plasma Free Glycosaminoglycans in Adults
Bratulic, S.; Limeta, A.; Maccari, F.; Galeotti, F.; Volpi, N.; Levin, M.; Nielsen, J.; Gatto, F.
10.1101/2021.05.21.445098 — biochemistry — Posted on 2021-09-29
206 Protein visualization and manipulation in Drosophila through the use of epitope tags recognized by nanobodies
Xu, J.; Kim, A.-R.; Cheloha, R. W.; Fischer, F. A.; Li, J. S. S.; Feng, Y.; Stoneburner, E.; Binari, R.; Mohr, S.; Zirin, J.; Ploegh, H.; Perrimon, N.
10.1101/2021.04.16.440240 — genetics — Posted on 2021-09-29
208 Growing Glycans in Rosetta: Accurate de novo glycan modeling, density fitting, and rational sequon design
Adolf-Bryfogle, J.; Labonte, J. W.; Kraft, J. C.; Shapovalov, M.; Raemisch, S.; Lutteke, T.; Dimaio, F.; Bahl, C. D.; Pallesen, J.; King, N. P.; Gray, J. J.; Kulp, D. W.; Schief, W. R.
10.1101/2021.09.27.462000 — molecular biology — Posted on 2021-09-29
209 Iron Status Influences Mitochondrial Disease Progression in Complex I-Deficient Mice
Grillo, A. S.; Kelly, C.; Ha, V. T.; Bodart, C. M.; Huff, S.; Couch, R. K.; Herrel, N. T.; Kim, H. D.; Zimmermann, A. O.; Shattuck, J.; Pan, Y.-C.; Kaeberlein, M.
10.1101/2021.09.29.462431 — molecular biology — Posted on 2021-09-29
210 Streptococcus pneumoniae rapidly translocates from the nasopharynx through the cribriform plate to invade and inflame the dura
Audshasai, T.; Coles, J. A.; Panagiotou, S.; Khandaker, S.; Scales, H. E.; Kjos, M.; Baltazar, M.; Vignau, J.; Brewer, J. M.; Kadioglu, A.; Yang, M.
10.1101/2021.09.28.462246 — microbiology — Posted on 2021-09-29
211 Intragenic proviral elements support transcription of defective HIV-1 proviruses
Kuniholm, J.; Armstrong, E.; Bernabe, B.; Coote, C.; Berenson, A.; Drinan, S.; Olson, A.; He, X.; Lin, N.; Fuxman Bass, J.; Henderson, A. J.
10.1101/2021.09.29.462330 — microbiology — Posted on 2021-09-29
212 Keap1 recognizes EIAV early accessory protein Rev to promote antiviral defense
Wang, Y.; Ma, G.; Wang, X.-F.; Na, L.; Guo, X.; Zhang, J.; Liu, C.; Du, C.; Lin, Y.; Wang, X.
10.1101/2021.09.29.462336 — microbiology — Posted on 2021-09-29
213 Much more than a toxin: hydrogen cyanide is a volatile modulator of bacterial behaviour
Anand, A.; Falquet, L.; Abou-Mansour, E.; L'Haridon, F.; Keel, C.; Weisskopf, L.
10.1101/2021.09.29.462390 — microbiology — Posted on 2021-09-29
216 Exploration of BAY 11-7082 as a novel antibiotic
Coles, V. E.; Darveau, P.; Zhang, X.; Harvey, H.; Henriksbo, B. D.; Yang, A.; Schertzer, J.; Magolan, J.; Burrows, L. L.
10.1101/2021.09.28.462244 — microbiology — Posted on 2021-09-29
217 Predicting speech from a cortical hierarchy of event-based timescales
Schmitt, L.-M.; Erb, J.; Tune, S.; Rysop, A.; Hartwigsen, G.; Obleser, J.
10.1101/2020.12.19.423616 — neuroscience — Posted on 2021-09-29
218 Harmonicity aids hearing in noise
McPherson, M. J.; Grace, R. C.; McDermott, J. H.
10.1101/2020.09.30.321000 — neuroscience — Posted on 2021-09-29
219 Neural circuits for dynamics-based segmentation of time series
Tesileanu, T.; Golkar, S.; Nasiri, S.; Sengupta, A. M.; Chklovskii, D. B.
10.1101/2021.04.23.441218 — neuroscience — Posted on 2021-09-29
220 Drosophila nicotinic acetylcholine receptor subunits and their native interactions with insecticidal peptide toxins
Korona, D.; Dirnberger, B.; Giachello, C. N. G.; Queiroz, R. M. L.; Minde, D.-P.; Deery, M. J.; Johnson, G.; Mueller, K. H.; Firth, L. C.; Earley, F. G.; Russell, S.; Lilley, K. S.
10.1101/2021.08.13.456240 — neuroscience — Posted on 2021-09-29
222 Temporal change in chromatin accessibility predicts regulators of nodulation in Medicago truncatula
Knaack, S. A.; Conde, D.; Balmant, K. M.; Irving, T. B.; Gontijo Silva Maia, L.; Triozzi, P. M.; Dervinis, C.; Pereira, W. J.; Maeda, J.; Chakraborty, S.; Schmidt, H. W.; Ane, J.-M.; Kirst, M.; Roy, S.
10.1101/2021.08.07.455463 — plant biology — Posted on 2021-09-29
225 Development of an in-situ printing system with human platelet lysate-based bio-adhesive to treat corneal perforation
You, J.; Frazer, H.; Sayyar, S.; Chen, Z.; Liu, X.; Taylor, A.; Filippi, B.; Wise, I.; Hodge, C.; Wallace, G.; Sutton, G.
10.1101/2021.09.13.460167 — bioengineering — Posted on 2021-09-29
226 Two helices control the dynamic crosstalk between the catalytic domains of LRRK2
Weng, J.-H.; Aoto, P. C.; Lorenz, R.; Wu, J.; Schmidt, S. H.; Manschwetus, J. T.; Kaila-Sharma, P.; Mathea, S.; Knapp, S.; Herberg, F. W.; Taylor, S. S.
10.1101/2021.09.29.462278 — biochemistry — Posted on 2021-09-29
227 Versatile and Robust Method for Antibody Conjugation to Nanoparticles with High Targeting Efficiency
Van Zundert, I.; Bravo, M.; Deschaume, O.; Cybulski, P.; Bartic, C.; Hofkens, J.; Uji-i, H.; Fortuni, B.; Rocha, S.
10.1101/2021.09.29.462399 — biochemistry — Posted on 2021-09-29
228 Biochemical and structural characterization of the fused Bacteroides fragilis NFeoAB domain reveals a role for FeoA
Sestok, A. E.; Brown, J. B.; Obi, J. O.; O'Sullivan, S. M.; Garcin, E. D.; Deredge, D.; Smith, A. T.
10.1101/2021.09.29.462438 — biochemistry — Posted on 2021-09-29
231 Better tired than lost: turtle ant trail networks favor coherence over shortest edges
Chandrasekhar, A.; Marshall, J. A. R.; Austin, C.; Navlakha, S.; Gordon, D. M.
10.1101/714410 — ecology — Posted on 2021-09-29
232 Linking null models to hypotheses to improve nestedness analysis
Pinheiro, R. B. P.; Dormann, C. F.; Felix, G. M.; Mello, M. A. R.
10.1101/2021.04.05.438470 — ecology — Posted on 2021-09-29
233 Responses of tree species traits to soil variation in the Cerrado
Meira-Neto, J. A. A.; Tolentino, G.; Buttschardt, T.; Maguas, C.
10.1101/2020.02.20.955955 — ecology — Posted on 2021-09-29
234 Unique functions for Notch4 in murine embryonic lymphangiogenesis
Muley, A.; Kim Uh, M.; Salazar-De Simone, G.; Swaminathan, B.; James, J. M.; Murtomaki, A.; McCarron, J. D.; Kitajewski, C.; Gnarra, M.; Riitano, G.; Mukouyama, Y.-s.; Kitajewski, J.; Shawber, C. J.
10.1101/2021.02.19.431982 — developmental biology — Posted on 2021-09-29
237 GpsB coordinates cell division and cell surface decoration by wall teichoic acids in Staphylococcus aureus
Hammond, L. R.; Khan, S. J.; Sacco, M. D.; Spanoudis, C.; Hough, A.; Chen, Y.; Eswara, P. J.
10.1101/2021.09.29.462461 — microbiology — Posted on 2021-09-29
241 An international report on bacterial communities in esophageal squamous cell carcinoma
Nomburg, J.; Bullman, S.; Nasrollahzadeh, D.; Collisson, E. A.; Abedi-Ardekani, B.; Akoko, L. O.; Atkins, J. R.; Buckle, G. C.; Gopal, S.; Hu, N.; Kaimila, B.; Khoshnia, M.; Malekzadeh, R.; Menya, D.; Mmbaga, B. T.; Moody, S.; Mulima, G.; Mushi, B. P.; Mwaiselage, J.; Mwanga, A.; Newton, Y.; Ng, D. L.; Radenbaugh, A.; Rwakatema, D. S.; Selekwa, M.; Schüz, J.; Taylor, P. R.; Vaske, C.; Goldstein, A.; Stratton, M. R.; McCormack, V.; Brennan, P.; DeCaprio, J. A.; Meyerson, M.; Mmbaga, E. J.; Van Loon, K.
10.1101/2021.09.29.462325 — microbiology — Posted on 2021-09-29
242 Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity.
Feriotti, C.; sa-Pessoa Graca Santos, J.; Calderon-Gonzalez, R.; Gu, L.; Morris, B.; Sugisawa, R.; Insua, J. L.; Carty, M.; Dumigan, A.; Ingram, R.; Kissenpfening, A.; Bowie, A. G.; Bengoechea, J. A.
10.1101/2021.09.29.462388 — microbiology — Posted on 2021-09-29
246 A revised mechanism for how Plasmodium falciparum recruits and exports proteins into its erythrocytic host cell.
Gabriela, M.; Matthews, K.; Boshoven, C.; Kouskousis, B.; Steer, D.; Jonsdottir, T.; Bullen, H.; Sleebs, B.; Crabb, B.; Koning-Ward, T.; Gilson, P.
10.1101/2021.09.29.462329 — microbiology — Posted on 2021-09-29
247 Infectivity of three Mayaro Virus (Genus Alphavirus, Family Togaviridae) geographic isolates in human cell lines
Patel, A. R.; Dulcey, M.; Abid, N.; Cash, M. N.; Dailey, J.; Salemi, M.; Mavian, C.; Vittor, A. Y.
10.1101/2021.09.29.462323 — microbiology — Posted on 2021-09-29
248 Monoclonal antibodies targeting surface exposed epitopes of Candida albicans cell wall proteins confer in vivo protection in an infection model
Palliyil, S.; Mawer, M.; Alwafi, S.; Fogg, L.; Buda De Cesare, G.; Tan, T.; Walker, L. A.; MacCallum, D.; Porter, A.; Munro, C. A.
10.1101/2021.09.29.462385 — microbiology — Posted on 2021-09-29
250 In silico screening of TMPRSS2 SNPs that affect its binding with SARS-CoV2 spike protein and directly involved in the interaction affinity changes
Nouira, F.; Hamdi, M.; Redissi, A.; Kouidhi, S.; Charfeddine, C.; Msaad, M.; Cherif, A.; Messaoud, S.; Aldulaijan, S.; Raouafi, N.; Dhouib, A.; Mosbah, A.
10.1101/2021.09.29.462283 — bioinformatics — Posted on 2021-09-29
251 Full genome Nobecovirus sequences from Malagasy fruit bats define a unique evolutionary history for this coronavirus clade
Kettenburg, G.; Kistler, A. L.; Ranaivoson, H. C.; Andry, S.; DeRisi, J. L.; Gentles, A.; Raharinosy, V.; Randriambolamanantsoa, T. H.; Ravelomanantsoa, N. A. F.; Tato, C. M.; Dussart, P.; Heraud, J.-M.; Brook, C. E.
10.1101/2021.09.29.462406 — evolutionary biology — Posted on 2021-09-29
252 SARS-CoV-2 variants of concern infect the respiratory tract and induce inflammatory response in wild-type laboratory mice
Stone, S.; Rothan, H. A.; Natekar, J. P.; Kumari, P.; Sharma, S.; Pathak, H.; Arora, K.; Aurani, T. T.; Kumar, M.
10.1101/2021.09.29.462373 — microbiology — Posted on 2021-09-29
254 Measuring competitive exclusion in non-small cell lung cancer
Farrokhian, N.; Maltas, J.; Dinh, M.; Durmaz, A.; Ellsworth, P.; Hitomi, M.; McClure, E.; Marusyk, A.; Kaznatcheev, A.; Scott, J. G.
10.1101/2020.09.18.303966 — cancer biology — Posted on 2021-09-29
256 Data-driven approaches for genetic characterization of SARS-CoV-2 lineages
Mostefai, F.; Gamache, I.; Huang, J.; N'Guessan, A.; Pelletier, J.; Pesaranghader, A.; Hamelin, D.; Murall, C. L.; Poujol, R.; Grenier, J.-C.; Smith, M.; Caron, E.; Craig, M.; Shapiro, J.; Wolf, G.; Krishnaswamy, S.; Hussin, J.
10.1101/2021.09.28.462270 — bioinformatics — Posted on 2021-09-29
257 Metabolic snapshot of plasma samples reveals new pathways implicated in SARS-CoV-2 pathogenesis
Alboniga, O. E.; Jimenez, D.; Sanchez-Conde, M.; Vizcarra, P.; Ron, R.; Herrera, S.; Martinez-Sanz, J.; Moreno, E.; Moreno, S.; Barbas, C.; Serrano-Villar, S.
10.1101/2021.09.29.462326 — biochemistry — Posted on 2021-09-29
258 A combination of two human neutralizing antibodies prevents SARS-CoV-2 infection in rhesus macaques
Cobb, R. R.; Nkolola, J.; Gilchuk, P.; Chandrashekar, A.; House, R. V.; Earnhart, C. G.; Dorsey, N. M.; Hopkins, S. A.; Snow, D. M.; Chen, R. E.; VanBlargan, L. A.; Hechenblaickner, M.; Hoppe, B.; Collins, L.; Tomic, M. T.; Nonet, G. H.; Hackett, K.; Slaughter, J. C.; Diamond, M. S.; Carnahan, R. H.; Barouch, D. H.; Crowe, J. E.
10.1101/2021.09.27.462074 — immunology — Posted on 2021-09-29
259 Use of eVLP-based vaccine candidates to broaden immunity against SARS-CoV-2 variants
Bozic, J.; Ahmed, T.; Ontsouka, B.; Fluckiger, A.-C.; Diress, A.; Berthoud, T.; Yuan, X.; Yang, L.; Diaz-Mitoma, F.; Anderson, D. E.; Soare, C.
10.1101/2021.09.28.462109 — immunology — Posted on 2021-09-29
260 A virus-specific monocyte inflammatory phenotype is induced by SARS-CoV2 at the immune-epithelial interface
Leon, J.; Michelson, D. A.; Olejnik, J.; Chowdhary, K.; Oh, H. S.; Hume, A. J.; Galvan-Pena, S.; Zhu, Y.; Chen, F.; Vijaykumar, B.; Yang, L.; Crestani, E.; Yonker, L. M.; Knipe, D. M.; Muhlberger, E.; Benoist, C.
10.1101/2021.09.29.462202 — immunology — Posted on 2021-09-29
261 Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody
Torres, J. L.; Ozorowski, G.; Andreano, E.; Liu, H.; Copps, J.; Piccini, G.; Donnici, L.; Conti, M.; Planchais, C.; Planas, D.; Manganaro, N.; Pantano, E.; Paciello, I.; Pileri, P.; Bruel, T.; Montomoli, E.; Mouquet, H.; Schwartz, O.; Sala, C.; De Francesco, R.; Wilson, I. A.; Rapuoli, R.; Ward, A. B.
10.1101/2021.09.28.462234 — immunology — Posted on 2021-09-29
268 A Mediterranean-like fat blend protects against the development of severe colitis in the mucin-2 deficient murine model
Haskey, N.; Ye, J.; Estaki, M.; Verdugo-Meza, A.; Barnett, J. A.; Yousefi, M.; Birnie, B.; Gruenheid, S.; Ghosh, S.; Gibson, D. L.
10.1101/2021.09.27.462042 — immunology — Posted on 2021-09-29
271 The impact of genetic risk for Alzheimers disease on the structural brain networks of young adults
Mirza-Davies, A.; Foley, S.; Caseras, X.; Baker, E.; Holmans, P.; Escott-Price, V.; Jones, D. K.; Harrison, J. R.; Messaritaki, E.
10.1101/2021.09.22.461338 — neuroscience — Posted on 2021-09-29
272 Temporal analysis of enhancers during mouse brain development reveals dynamic regulatory function and identifies novel regulators of cerebellar development.
Ramirez, M.; Badayeva, Y.; Yeung, J.; Wu, J. P. H.; Yang, E.; FANTOM 5 Consortium, ; Trost, B.; Scherer, S. W.; Goldowitz, D.
10.1101/2021.09.28.461416 — neuroscience — Posted on 2021-09-29
273 PhycoMine: A Microalgae Data Warehouse
Dorado Goitia, R. R.; Riano-Pachon, D. M.; Fassio, A. V.; Winck, F. V.
10.1101/2021.09.27.462046 — systems biology — Posted on 2021-09-29
277 3D U-Net improves automatic brain extraction for isotropic rat brain MRI data
Hsu, L.; Wang, S.; Walton, L.; Wang, T.-W. W.; Lee, S.-H.; Shih, Y.-Y. I.
10.1101/2021.09.27.462020 — bioinformatics — Posted on 2021-09-29
278 PlasmidHostFinder: Prediction of plasmid hosts using random forest
Aytan-Aktug, D.; CLAUSEN, P. T.; Szarvas, J.; Munk, P.; Otani, S.; Nguyen, M.; Davis, J. J.; Lund, O.; Aarestrup, F. M.
10.1101/2021.09.27.462084 — bioinformatics — Posted on 2021-09-29
281 Tuning epithelial cell-cell adhesion and collective dynamics with functional DNA-E-cadherin hybrid linkers
Schoenit, A.; Lo Giudice, C.; Hahnen, N.; Ollech, D.; Jahnke, K.; Goepfrich, K.; Cavalcanti-Adam, E. A.
10.1101/2021.09.27.462021 — bioengineering — Posted on 2021-09-29
286 Mutational signature profiling classifies subtypes of clinically different mismatch repair deficient tumors with a differential immunogenic response potential
Giner-Calabuig, M.; De Leon, S.; Wang, J.; Fehlmann, T.; Ukaegbu, C.; Gibson, J.; Alustiza Fernandez, M.; Pico, M.-D.; Alenda, C.; Herraiz, M.; Carrillo-Palau, M.; Salces, I.; Reyes, J.; Ortega, S. P.; Obrador, A.; Cecchini, M.; Syngal, S.; Stoffel, E.; Ellis, N. A.; Sweasy, J.; Jover, R.; Llor, X.; Xicola, R. M.
10.1101/2021.09.28.460630 — genomics — Posted on 2021-09-29
287 Immune function of the serosa in hemimetabolous insect eggs
Jacobs, C. G.; van der Hulst, R.; Chen, Y.-T.; Williamson, R. P.; Roth, S.; van der Zee, M.
10.1101/2021.09.27.462031 — evolutionary biology — Posted on 2021-09-29
289 Plant neighborhood shapes diversity and reduces interspecific variation of the phyllosphere microbiome
Meyer, K. M.; Porch, R.; Muscettola, I. E.; Vasconcelos, A. L. S.; Sherman, J. K.; Metcalf, C. J. E.; Lindow, S. E.; Koskella, B.
10.1101/2021.09.27.462052 — ecology — Posted on 2021-09-29
291 Extraembryonic endoderm cells induce neuroepithelial tissue in gastruloids
Berenger-Currias, N. M. L. P.; Mircea, M.; Adegeest, E.; van den Berg, P. R.; Feliksik, M.; Hochane, M.; Idema, T.; Tans, S.; Semrau, S.
10.1101/2020.02.13.947655 — developmental biology — Posted on 2021-09-29
293 Targeted biallelic integration of an inducible Caspase 9 suicide gene for safer cellular therapies prevents development of drug-resistant escapees in human iPSCs
Wunderlich, S.; Haase, A.; Merkert, S.; Jahn, K.; Deest, M.; Glage, S.; Korte, W.; Martens, A.; Kirschning, A.; Zeug, A.; Ponimaskin, E.; Goehring, G.; Ackermann, M.; Lachmann, N.; Moritz, T.; Zweigerdt, R.; Martin, U.
10.1101/2021.09.19.460940 — molecular biology — Posted on 2021-09-29
294 Truncated denitrifiers dominate the denitrification pathway in tundra soil metagenomes
Pessi, I. S.; Viitamaki, S.; Virkkala, A.-M.; Eronen-Rasimus, E.; Delmont, T. O.; Marushchak, M. E.; Luoto, M.; Hultman, J.
10.1101/2020.12.21.419267 — microbiology — Posted on 2021-09-29
295 MNPmApp: An image analysis tool to quantify mononuclear phagocyte distribution in mucosal tissues
Potts, C.; Schearer, J.; Bair, D.; Ayler, B.; Love, J.; Dankoff, J.; Harris, P. D.; Zosso, D.; Bimczok, D.
10.1101/2021.09.27.461889 — immunology — Posted on 2021-09-29
299 Blind cavefish retain functional connectivity in the tectum despite loss of retinal input
Lloyd, E.; McDole, B.; Privat, M.; Jaggard, J. B.; Duboue, E. R.; Sumbre, G.; Keene, A. C.
10.1101/2021.09.28.461408 — neuroscience — Posted on 2021-09-29
303 Tuna-AI: tuna biomass estimation with Machine Learning models trained on oceanography and echosounder FAD data
Precioso, D.; Navarro-Garcia, M.; Gavira-O'Neill, K.; Torres-Barran, A.; Gordo, D.; Gallego-Alcala, V.; Gomez-Ullate, D.
10.1101/2021.09.15.460261 — bioinformatics — Posted on 2021-09-29
305 Recruitment of CTCF to an Fto enhancer is responsible for transgenerational inheritance of obesity
Jung, Y. H.; Wang, H.-L. V.; Ruiz, D.; Grandi, F. C.; Bixler, B. J.; Linsenbaum, H.; Xiang, J.-F.; Shafik, A. M.; Jin, P.; Corces, M. R.; Corces, V. G.
10.1101/2020.11.20.391672 — genomics — Posted on 2021-09-29
306 Midcell localization of PBP4 of Escherichia coli is modulating the timing of divisome assembly
Verheul, J.; Lodge, A.; Yau, H.; Liu, X.; Liu, X.; Solovyova, A. S.; Typas, A.; Banzhaf, M.; Vollmer, W.; den Blaauwen, T.
10.1101/2020.07.30.230052 — microbiology — Posted on 2021-09-29
307 CNpare: matching DNA copy number profiles
Chaves-Urbano, B.; Hernando, B.; Garcia, M. J.; Macintyre, G.
10.1101/2021.09.28.462193 — bioinformatics — Posted on 2021-09-29
309 Machine learning modeling of protein-intrinsic features predicts tractability of targeted protein degradation
Zhang, W.; Roy Burman, S. S.; Chen, J.; Donovan, K. A.; Cao, Y.; Zhang, B.; Zeng, Z.; Zhang, Y.; Li, D.; Fischer, E. S.; Tokheim, C.; Liu, X. S.
10.1101/2021.09.27.462040 — bioinformatics — Posted on 2021-09-29
312 mTOR inhibition enhances delivery and activity of antisense oligonucleotides in uveal melanoma cells
Dewaele, S.; Delhaye, L.; De Paepe, B.; Bogaert, B.; Martinez, R.; Anckaert, J.; Yigit, N.; Nuytens, J.; Van Coster, R.; Eyckerman, S.; Raemdonck, K.; Mestdagh, P.
10.1101/2021.09.29.462324 — cancer biology — Posted on 2021-09-29
314 Comprehensive analysis of mutational signatures in pediatric cancers
Thatikonda, V.; Islam, S. M. A.; Jones, B. C.; Groebner, S. N.; Warsow, G.; Hutter, B.; Huebschmann, D.; Froehling, S.; Blattner-Johnson, M.; Jones, D. T. W.; Alexandrov, L. B.; Pfister, S. M.; Jaeger, N.
10.1101/2021.09.28.462210 — cancer biology — Posted on 2021-09-29
315 Disentangling heterogeneity of Malignant Pleural Mesothelioma through deep integrative omics analyses
Mangiante, L.; Alcala, N.; Di Genova, A.; Sexton-Oates, A.; Gonzalez-Perez, A.; Khandekar, A.; Bergstrom, E.; Kim, J.; Giacobi, C.; Le-Stang, N.; Boyault, S.; Cuenin, C.; Tabone-Eglinger, S.; Damiola, F.; Voegele, C.; Ardin, M.; Michallet, M.-C.; Soudade, L.; Delhomme, T.; Poret, A.; Brevet, M.; Copin, M.-C.; Giusiano-Courcambeck, S.; Damotte, D.; Girard, C.; Hofman, V.; Hofman, P.; Mouroux, J.; Lacomme, S.; Mazieres, J.; Thomas de Montpreville, V.; Perrin, C.; Planchard, G.; Rouquette, I.; Sagan, C.; Scherpereel, A.; Thivolet, F.; Vignaud, J.-M.; Jean, D.; Gilg Soit Ilg, A.; Olaso, R.; Meyer,
10.1101/2021.09.27.461908 — cancer biology — Posted on 2021-09-29
317 The Impact of Neuron Morphology on Cortical Network Architecture
Udvary, D.; Harth, P.; Macke, J. H.; Hege, H.-C.; de Kock, C. P. J.; Sakmann, B.; Oberlaender, M.
10.1101/2020.11.13.381087 — neuroscience — Posted on 2021-09-29
318 Integrative analysis allows a global and precise identification of functional miRNA target genes in mESCs
Schaefer, M.; Nabih, A.; Spies, D.; Bodak, M.; Wischnewski, H.; Stalder, P.; Ngondo, R. P.; Liechti, L. A.; Sajic, T.; Aebersold, R.; Gatfield, D.; Ciaudo, C.
10.1101/2021.09.24.461622 — systems biology — Posted on 2021-09-29
319 Ssl2/TFIIH Function in Transcription Start Site Scanning by RNA Polymerase II in Saccharomyces cerevisiae
Zhao, T.; Vvedenskaya, I. O.; Lai, W. K. M.; Basu, S.; Pugh, B. F.; Nickels, B. E.; Kaplan, C. D.
10.1101/2021.05.05.442816 — molecular biology — Posted on 2021-09-28
320 Exploration of 1 BAY 11-7082 as a novel antibiotic
Coles, V. E.; Darveau, P.; Zhang, X.; Harvey, H.; Henriksbo, B. D.; Yang, A.; Schertzer, J.; Magolan, J.; Burrows, L. L.
10.1101/2021.09.28.462244 — microbiology — Posted on 2021-09-28
321 Microbiological quality assessment of five common foods sold at different points of sale in Burkina-Faso
COMPAORE, M. K. A.; KPODA, S. D.; BAZIE, R. B. S.; OUEDRAOGO, M.; YAKORO, A.; NIKIEMA, F.; BELEMLOUGRI, A.; MEDA, R.; BANDE, M.; BARRO, N.; KABRE, E.
10.1101/2021.09.28.462219 — microbiology — Posted on 2021-09-28
324 Conservation and convergence of genetic architecture in the adaptive radiation of Anolis lizards
McGlothlin, J. W.; Kobiela, M. E.; Wright, H. V.; Kolbe, J. J.; Losos, J. B.; Brodie, E. D.
10.1101/2021.02.18.431064 — evolutionary biology — Posted on 2021-09-28
326 HIV-specific CD8 T cells from elite controllers have an epigenetic imprint that preserves effector functions
Frias, A. B.; Rutishauser, R. L.; Sharma, A. A.; Mi, T.; Zebley, C.; Constantz, C. M.; Abdelsamed, H. A.; Stone, M.; Busch, M. P.; Deeks, S.; Sekaly, R.-P.; Youngblood, B.
10.1101/2021.09.28.459512 — immunology — Posted on 2021-09-28
329 Towards a unified theory of plant photosynthesis and hydraulics
Joshi, J.; Stocker, B. D.; Hofhansl, F.; Zhou, S.; Dieckmann, U.; Prentice, I. C.
10.1101/2020.12.17.423132 — plant biology — Posted on 2021-09-28
330 Unidirectional Single-File Transport of Full-Length Proteins Through a Nanopore
Yu, L.; Kang, X.; Li, F.; Mehrafrooz, B.; Makhamreh, A.; Fallahi, A.; Aksimentiev, A.; Chen, M.; Wanunu, M.
10.1101/2021.09.28.462155 — biophysics — Posted on 2021-09-28
335 Designing viral diagnostics with model-based optimization
Metsky, H. C.; Welch, N. L.; Pillai, P. P.; Haradhvala, N. J.; Rumker, L.; Mantena, S.; Zhang, Y. B.; Yang, D. K.; Ackerman, C. M.; Weller, J.; Blainey, P. C.; Myhrvold, C.; Mitzenmacher, M.; Sabeti, P. C.
10.1101/2020.11.28.401877 — genomics — Posted on 2021-09-28
339 Reticular Dysgenesis-associated Adenylate Kinase 2 deficiency causes failure of myelopoiesis through disordered purine metabolism
Wang, W.; DeVilbiss, A.; Arreola, M.; Mathews, T.; Zhao, Z.; Martin-Sandoval, M.; Benegiamo, G.; Awani, A.; Goeminne, L.; Dever, D.; Nakauchi, Y.; Pavel-Dinu, M.; Al-Herz, W.; Noratangelo, L.; Porteus, M. H.; Auwerx, J.; Morrison, S. J.; Weinacht, K. G.
10.1101/2021.07.05.450633 — cell biology — Posted on 2021-09-28
342 Influenza A virus undergoes compartmentalized replication in vivo dominated by stochastic bottlenecks
Amato, K. A.; Haddock, L. A.; Braun, K. M.; Meliopoulos, V.; Livingston, B.; Honce, R.; Schaack, G. A.; Boehm, E.; Higgins, C. A.; Barry, G. L.; Koelle, K.; Schultz-Cherry, S.; Friedrich, T. C.; Mehle, A.
10.1101/2021.09.28.462198 — microbiology — Posted on 2021-09-28
346 Ovipin: a chicken eggs antibiotic agent
dos Santos, S. R.; Miranda, A.; Silva Junior, P. I.
10.1101/2021.09.28.462162 — microbiology — Posted on 2021-09-28
349 Learning about threat from friends and strangers is equally effective: an fMRI study on observational fear conditioning
Kazmierowska, A. M.; Szczepanik, M.; Wypych, M.; Drozdziel, D.; Marchewka, A.; Michalowski, J. M.; Olsson, A.; Knapska, E.
10.1101/2021.09.20.461036 — neuroscience — Posted on 2021-09-28
351 Defining hierarchical protein interaction networks from spectral analysis of bacterial proteomes
Zaydman, M. A.; Little, A.; Haro, F.; Aksianiuk, V.; Buchser, W.; DiAntonio, A.; Gordon, J. I.; Milbrandt, J.; Raman, A.
10.1101/2021.09.28.462107 — systems biology — Posted on 2021-09-28
353 Expanding the Molecular Alphabet of DNA-Based Data Storage Systems with Neural Network Nanopore Readout Processing
Tabatabaei, S. K.; Pham, B.; Pan, C.; Liu, J.; Chandak, S.; Shorkey, S. A.; Hernandez, A. G.; Aksimentiev, A.; Chen, M.; Schroeder, C. M.; Milenkovic, O.
10.1101/2021.09.27.462049 — synthetic biology — Posted on 2021-09-28
355 Pioneer transcription factors are associated with the modulation of DNA methylation patterns across cancers
Berhanu Lemma, R.; Fleischer, T.; Martinsen, E.; Ledsaak, M.; Kristensen, V. N.; Eskeland, R.; Gabrielsen, O. S.; Mathelier, A.
10.1101/2021.05.10.443359 — cancer biology — Posted on 2021-09-28
359 A Chimeric Peptide Inhibits Red Blood Cell Invasion by Plasmodium falciparum with Hundredfold Increased Efficacy
Mannuthodikayil, J.; Sinha, S.; Singh, S.; Biswas, A.; Ali, I.; Mashurabad, P. C.; Tabassum, W.; Vydyam, P.; Bhattacharyya, M. K.; Mandal, K.
10.1101/2021.09.28.462119 — biochemistry — Posted on 2021-09-28
360 The evolution of splicing: transcriptome complexity and transcript distances implemented in TranD
Nanni, A. V.; Titus-McQuillan, J.; Moskalenko, O.; Pardo-Palacios, F.; Liu, Z.; Conesa, A.; Rodgers, R.; McIntyre, L.
10.1101/2021.09.28.462251 — genomics — Posted on 2021-09-28
362 High-resolution genetic mapping of the mucosa-associated gut microbiome in hybrid mice provides novel insight on the impact of host genetics
Doms, S.; Fokt, H.; Ruehlemann, M. C.; Chung, C. J.; Kuenstner, A.; Ibrahim, S.; Franke, A.; Turner, L. M.; Baines, J. F.
10.1101/2021.09.28.462095 — genetics — Posted on 2021-09-28
366 Long-term experimental evolution decouples size and production costs in Escherichia coli
Marshall, D.; Malerba, M.; Lines, T.; Sezmis, A.; Hasan, C.; Lenski, R.; McDonald, M.
10.1101/2021.09.28.462250 — evolutionary biology — Posted on 2021-09-28
367 Cortical actin properties controlled by Drosophila Fos aid macrophage infiltration against surrounding tissue resistance
Belyaeva, V.; Wachner, S.; Gyoergy, A.; Emtenani, S.; Gridchyn, I.; Akhmanova, M.; Linder, M.; Roblek, M.; Sibilia, M.; Siekhaus, D.
10.1101/2020.09.18.301481 — cell biology — Posted on 2021-09-28
371 Milk casein prevents inactivation effect of black tea galloylated theaflavins on SARS-CoV-2 in vitro
Ohgitani, E.; Shin-Ya, M.; Ichitani, M.; Kobayashi, M.; Takihara, T.; Saito, M.; Kinugasa, H.; Mazda, O.
10.1101/2021.09.27.461930 — microbiology — Posted on 2021-09-28
372 Nasopharyngeal Microbiota as an early severity biomarker in COVID-19 hospitalised patients: a retrospective cohort study in a Mediterranean area.
Ventero, M. P.; Moreno-Perez, O.; Molina-Pardines, C.; Paytuvi-Gallart, A.; Boix, V.; Galan, I.; Gonzalez-delaAleja, P.; Lopez-Perez, M.; Sanchez-Martinez, R.; Merino, E.; Rodriguez, J. C.
10.1101/2021.09.28.461924 — microbiology — Posted on 2021-09-28
373 Beneficial Effects of Celastrol on Immune Balance by Modulating Gut Microbiota in Dextran Sodium Sulfate-Induced Ulcerative Colitis
Hu, D.; Li, M.; Guo, W.; Dong, Y.; Wang, W.; Tian, C.; Zhang, Z.; Yu, T.; Zhou, H.; Gui, Y.; Xue, K.; Li, J.; Jiang, F.; Sarapultsev, A.; Luo, S.; Fan, H.
10.1101/2021.09.28.462065 — microbiology — Posted on 2021-09-28
374 Exposure to nitric oxide drives transition to resuscitation-promoting factor-dependency in mycobacteria
Glenn, S. M.; Gap-Gaupool, B.; Waddell, S. J.; Bacon, J.; Crosatti, M.; Hincks, J.; Kendall, S. L.; Riabova, O.; Monakhova, N.; Green, J.; Turapov, O.; Makarov, V.; Mukamolova, G. V.
10.1101/2021.09.28.462152 — microbiology — Posted on 2021-09-28
375 ChAdOx1 nCoV-19 (AZD1222) vaccine elicits monoclonal antibodies with potent cross-neutralizing activity against SARS-CoV-2 viral variants
Seow, J.; Graham, C.; Hallett, S. R.; Lechmere, T.; Maguire, T. J. A.; Huettner, I.; Cox, D.; Roberts, R.; Waters, A.; Ward, C. C.; Mant, C.; Pitcher, M. J.; Spencer, J.; Fox, J.; Malim, M. H.; Doores, K. J.
10.1101/2021.09.27.461862 — immunology — Posted on 2021-09-28
381 Prophylactic efficacy of riluzole against anxiety- and depressive-like behaviors in two rodent stress models
Bansal, Y.; Fee, C.; Misquitta, K.; Codeluppi, S. A.-M.; Sibille, E.; Berman, R.; Coric, V.; Sanacora, G.; Banasr, M.
10.1101/2020.08.07.242057 — pharmacology and toxicology — Posted on 2021-09-28
382 Cascading Epigenomic Analysis for Identifying Disease Genes from the Regulatory Landscape of GWAS Variants
Ng, B.; Casazza, W.; Kim, N.; Wang, C.; Farhadi, F.; Tasaki, S.; Bennett, D. A.; De Jager, P. L.; Gaiteri, C.; Mostafavi, S.
10.1101/859512 — bioinformatics — Posted on 2021-09-28
385 Distinct cell adhesion signature defines glioblastoma myeloid-derived suppressor cell subsets
Bayik, D.; Bartels, C. F.; Lovrenert, K.; Watson, D.; Zhang, D.; Kay, K.; Lauko, A.; Johnson, S.; Lo, A.; McGraw, M.; Grabowski, M.; Mohammadi, A. M.; Veglia, F.; Fan, Y.; Vogelbaum, M. A.; Scacheri, P.; Lathia, J.
10.1101/2021.09.27.461995 — immunology — Posted on 2021-09-28
386 The BNT162b2 mRNA vaccine induces polyfunctional T cell responses with features of longevity.
Borsellino, G.; Guerrera, G.; Picozza, M.; D'Orso, S.; Placido, R.; Pirronello, M.; Verdiani, A.; Termine, A.; Fabrizio, C.; Giannessi, F.; Sambucci, M.; Balice, M. P.; Caltagirone, C.; Salvia, A.; Rossini, A.; Battistini, L.
10.1101/2021.09.27.462006 — immunology — Posted on 2021-09-28
387 Leukocyte adhesion is governed by endolysosomal two pore channel 2 (TPC2)
Goretzko, J.; Heitzig, N.; Thomas, K.; Krogsaeter, E. K.; Nass, J.; Linard Matos, A. L.; Wegner, T.; Schloer, S.; Gerke, V.; Rossaint, J.; Glorius, F.; Bracher, F.; Grimm, C. M.; Rescher, U.
10.1101/2021.09.28.462104 — immunology — Posted on 2021-09-28
388 Deep Learning Enables Design of Multifunctional Synthetic Human Gut Microbiome Dynamics
Baranwal, M.; Clark, R. L.; Thompson, J.; Sun, Z.; Hero, A. O.; Venturelli, O. S.
10.1101/2021.09.27.461983 — systems biology — Posted on 2021-09-28
389 Seeing the unseen: A trifoliate (MYB117) mutant allele fortifies folate and carotenoids in tomato fruits
Tyagi, K.; Sunkum, A.; Rai, M.; Sarma, S.; Thakur, N.; Yadav, A.; Sircar, S.; Sreelakshmi, Y.; Sharma, R.
10.1101/2021.09.28.462071 — plant biology — Posted on 2021-09-28
391 Temporal Changes in Transcripts of MITE Transposable Elements during Rice Endosperm Development
Nagata, H.; Ono, A.; Tonosaki, K.; Kawakatsu, T.; Yano, K.; Kishima, Y.; Kinoshita, T.
10.1101/2021.09.27.461986 — plant biology — Posted on 2021-09-28
392 Inhibition of chloroplast translation as a new target for herbicides
Sukhoverkov, K. V.; Breese, K. J.; Debowski, A. W.; Murcha, M. W.; Stubbs, K. A.; Mylne, J. S.
10.1101/2021.09.28.462089 — plant biology — Posted on 2021-09-28
394 LORE homomerization is required for 3-OH-C10:0 induced immune signaling
Eschrig, S.; Schaeffer, M.; Illig, T.; Eibel, S.; Shu, L.-J.; Fernandez, A.; Ranf, S.
10.1101/2021.09.27.461997 — plant biology — Posted on 2021-09-28
405 The APC/CCCS52A2 E3-Ligase Complex targeted PKN1 Protein is a Plant Lineage-Specific Driver of Cell Division
Willems, A.; Liang, Y.; Heyman, J.; Eekhout, T.; Van den Daele, H.; Vercauteren, I.; De Veylder, L.
10.1101/2021.09.27.462019 — plant biology — Posted on 2021-09-28
406 A merger between compatible but divergent genomes supports allopolyploidization in the Brassicaceae family
Shin, H.; Park, J. E.; Park, H. R.; Choi, W. L.; Yu, S. H.; Koh, W.; Kim, S.; Soh, H. Y.; Waminal, N. E.; Belandres, H. R.; Lim, J. Y.; Yi, G.; Ahn, J. H.; Kim, J.-S.; Kim, Y.-M.; Koo, N.; Kim, K.; Perumal, S.; Kang, T.; Kim, J.; Jang, H.; Kang, D. H.; Kim, Y. S.; Jeong, H.-M.; Yang, J.; Song, S.; Park, S.; Kim, J. A.; Lim, Y. P.; Park, B.-S.; Hsieh, T.-F.; Yang, T.-J.; Choi, D.; Kim, H. H.; Lee, S.-S.; Huh, J. H.
10.1101/2021.09.28.462158 — plant biology — Posted on 2021-09-28
408 Expert-integrated automated machine learning uncovers hemodynamic predictors in spinal cord injury
Chou, A.; Torres-Espin, A.; Kyritsis, N.; Huie, J. R.; Khatry, S.; Funk, J.; Hay, J.; Lofgreen, A.; Shah, R.; McCann, C.; Pascual, L. U.; Amorim, E.; Weinstein, P. R.; Manley, G. T.; Dhall, S. S.; Pan, J. Z.; Bresnahan, J. C.; Beattie, M. S.; Whetstone, W. D.; Ferguson, A. R.; TRACK-SCI Investigators,
10.1101/2021.09.27.461544 — bioinformatics — Posted on 2021-09-28
410 Prime-seq, efficient and powerful bulk RNA-sequencing
Janjic, A.; Wange, L. E.; Bagnoli, J. W.; Geuder, J.; Nguyen, P.; Richter, D.; Vieth, B.; Vick, B.; Jeremias, I.; Ziegenhain, C.; Hellmann, I.; Enard, W.
10.1101/2021.09.27.459575 — genomics — Posted on 2021-09-28
414 Distinct neural representations for prosocial and self-benefitting effort
Lockwood, P.; Wittmann, M.; Nili, H.; Matsumoto-Ryan, M.; Abdurahman, A.; Cutler, J.; Husain, M.; Apps, M.
10.1101/2021.09.27.461936 — neuroscience — Posted on 2021-09-28
415 Compartment-specific tuning of hippocampal dendritic feature selectivity by intracellular Ca2+ release
O'Hare, J. K.; Hirabayashi, Y.; Hewitt, V. L.; Blockus, H.; Szoboszlay, M.; Rolotti, S. V.; Geiller, T. C.; Negrean, A.; Chelur, V.; Losonczy, A.; Polleux, F.
10.1101/2021.09.27.460811 — neuroscience — Posted on 2021-09-28
416 Fragile X syndrome patient-derived neurons developing in the mouse brain show FMR1 -dependent phenotypes
Krzisch, M. A.; Wu, H. A.; Yuan, B.; Whitfield, T. W.; Liu, X. S.; Fu, D.; Shih, J.; Garrett-Engele, C. M.; Chang, A. N.; Warren, S.; Cacace, A.; Andrykovich, K. A.; Rietjens, R. G. J.; Jain, B.; Wallace, O.; Sur, M.; Jaenisch, R.
10.1101/2021.09.27.461739 — neuroscience — Posted on 2021-09-28
420 Practices for Measuring 3D Organelle Morphology and Generating Surfaces with Amira
Garza Lopez, E.; Vue, Z.; Katti, P.; Neikirk, K.; Biete, M.; Lam, J.; Beasley, H.; Marshall, A.; Rodman, T.; Christensen, T. A.; Salisbury, J. L.; Vang, L.; Mungai, M.; AshShareef, S.; Murray, S.; Shao, J.; Streeter, J.; Glancy, B.; Pereira, R. O.; Abel, E. D.; Hinton, A.
10.1101/2021.09.25.461807 — biophysics — Posted on 2021-09-28
421 Biomimetic Vasculatures by 3D-Printed Porous Molds
Ching, T.; vasudevan, j.; Chang, S.-Y.; Tan, H. Y.; Lim, C. T.; Fernandez, J. G.; Ng, J. J.; Toh, Y.-C.; Hashimoto, M.
10.1101/2021.09.27.461981 — bioengineering — Posted on 2021-09-28
423 Leafy and Weedy Seadragon Genomes Connect Genic and Repetitive DNA Features to the Extravagant Biology of Syngnathid Fishes
Small, C. M.; Healey, H. M.; Currey, M. C.; Beck, E. A.; Catchen, J. M.; Lin, A. S.; Cresko, W. A.; Bassham, S.
10.1101/2021.09.24.461757 — genomics — Posted on 2021-09-28
424 Climate warming changes synchrony of plants and pollinators
Freimuth, J.; Bossdorf, O.; Scheepens, J. F.; Willems, F. M.
10.1101/2021.01.10.425984 — ecology — Posted on 2021-09-28
425 Optogenetic control of NOTCH1 signalling
Kałafut, J.; Czapinski, J.; Przybyszewska-Podstawka, A.; Czerwonka, A.; Sahlgren, C.; Rivero-Müller, A.
10.1101/2021.09.27.462029 — cell biology — Posted on 2021-09-28
427 Generation of iPSC lines with high cytogenetic stability from peripheral blood mononuclear cells (PBMCs)
Panther, L.; Ornelas, L.; Jones, M. R.; Gross, A. R.; Gomez, E.; Liu, C.; Berman, B.; Svendson, C. N.; Sareen, D.
10.1101/2021.09.27.462082 — cell biology — Posted on 2021-09-28
432 Predictive Maps in Rats and Humans for Spatial Navigation
de Cothi, W.; Nyberg, N.; Griesbauer, E.-M.; Ghaname, C.; Zisch, F.; Fletcher, L.; Newton, C.; Renaudineau, S.; Bendor, D.; Grieves, R.; Duvelle, E.; Barry, C.; Spiers, H. J.
10.1101/2020.09.26.314815 — animal behavior and cognition — Posted on 2021-09-28
434 Defects in plant immunity modulate the rates and patterns of RNA virus evolution
Navarro, R.; Ambros, S.; Butkovic, A.; Carrasco, J. L.; Gonzalez, R.; Martinez, F.; Wu, B.; Elena, S. F.
10.1101/2020.10.13.337402 — evolutionary biology — Posted on 2021-09-28
436 Reovirus infection is regulated by NPC1 and endosomal cholesterol homeostasis
Ortega Gonzalez, P.; Taylor, G. M.; Jangra, R.; Tenorio Vela, R.; Fernandez de Castro Martin, I.; Mainou, B.; Orchard, R.; Wilen, C. B.; Brigleb, P. A.; Sojati, J.; Chandran, K.; Risco, C.; Dermody, T. S.
10.1101/2021.09.27.462002 — cell biology — Posted on 2021-09-28
437 PCSK9 affects expression of key surface proteins in human pancreatic beta cells through intra- and extracellular regulatory circuits
Saitoski, k.; Ryaboshapkina, M.; Hamza, G.; Jarnuczak, A. F.; berthault, c.; Carlotti, F.; Armanet, M.; Sengupta, K.; Rye Underwood, C.; Andersson, S.; guillas_baudouin, I.; Le Goff, W.; Scharfmann, R.
10.1101/2021.09.28.461975 — cell biology — Posted on 2021-09-28
438 Small extracellular vesicles from iPSC-MSC lose their regenerative potential upon UV-C irradiation
Biani, M. C.; Lombardi, A.; Norris, A.; Bucci, P.; La Greca, A.; Waisman, A.; Moro, L. N.; Sevlever, G.; Montanari, J.; Miriuka, S. G.; Luzzani, C.
10.1101/2021.09.27.461979 — cell biology — Posted on 2021-09-28
439 A serotonergic axon-cilium synapse drives nuclear signaling to maintain chromatin accessibility
Sheu, S.-H.; Upadhyayula, S.; Dupuy, V.; Pang, S.; Lemire, A. L.; Walpita, D.; Pasolli, H. A.; Deng, F.; Wan, J.; Wang, L.; Houser, J.; Sanchez-Martinez, S.; Brauchi, S. E.; Banala, S.; Freeman, M.; Xu, C. S.; Kirchhausen, T.; Hess, H. F.; Lavis, L.; Li, Y.-L.; Chaumont-Dubel, S.; Clapham, D. E.
10.1101/2021.09.27.461878 — cell biology — Posted on 2021-09-28
441 Transcription and splicing dynamics during early Drosophila development
Prudencio, P.; Savisaar, R.; Rebelo, K.; Martinho, R. G.; Carmo-Fonseca, M.
10.1101/2020.11.05.367888 — molecular biology — Posted on 2021-09-28
442 Interactions of cytosolic termini of the Jen1 monocarboxylate transporter are critical for trafficking, transport activity and endocytosis
Barata Antunes, C.; Talaia, G.; Broutzakis, G.; Ribas, D.; De Beule, P.; Casal, M.; Stefan, C. J.; Diallinas, G.; Paiva, S.
10.1101/2021.09.27.461913 — microbiology — Posted on 2021-09-28
445 The activities of LRRK2 and GCase are positively correlated in clinical biospecimens and experimental models of Parkinson's disease
Kedariti, M.; Frattini, E.; Baden, P.; Cogo, S.; Civiero, L.; Ziviani, E.; Aureli, M.; Kaganovich, A.; Cookson, M. R.; Stefanis, L. R.; Surface, M.; Deleidi, M.; Di Fonzo, A.; Alcalay, R. N.; Rideout, H.; Greggio, E.; Plotegher, N.
10.1101/2021.09.27.461935 — neuroscience — Posted on 2021-09-28
446 Towards optimization of oscillatory stimulation during sleep
Ladenbauer, J.; Khakimova, L.; Malinowski, R.; Obst, D.; Tonnies, E.; Antonenko, D.; Obermayer, K.; Hanna, J.; Floel, A.
10.1101/2021.09.27.461932 — neuroscience — Posted on 2021-09-28
449 Midkine noncanonically suppresses AMPK activation through disrupting the LKB1-STRAD-Mo25 complex
Xia, T.; Chen, D.; Liu, X.; Qi, H.; Wang, W.; Chen, H.; Ling, T.; Otkur, W.; Zhang, C.-S.; Kim, J.; Lin, S.-C.; Piao, H.-l.
10.1101/2021.09.27.462083 — cancer biology — Posted on 2021-09-28
451 Spatiotemporal co-dependency between macrophages and exhausted CD8+ T cells in cancer
Kersten, K.; Hu, K. H.; Combes, A. J.; Samad, B.; Harwin, T.; Ray, A.; Rao, A. A.; Cai, E.; Marchuk, K.; Artichoker, J.; Courau, T.; Shi, Q.; Belk, J.; Satpathy, A. T.; Krummel, M. F.
10.1101/2021.09.27.461866 — cancer biology — Posted on 2021-09-28
454 Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data
Zhang, M. J.; Hou, K.; Dey, K. K.; Jagadeesh, K. A.; Weinand, K.; Sakaue, S.; Taychameekiatchai, A.; Rao, P.; Pisco, A. O.; Zou, J.; Wang, B.; Gandal, M.; Raychaudhuri, S.; Pasaniuc, B.; Price, A. L.
10.1101/2021.09.24.461597 — bioinformatics — Posted on 2021-09-28
459 The exocyst complex and intracellular vesicles mediate soluble protein trafficking to the primary cilium
Niedziołka, S. M.; Datta, S.; Uspienski, T.; Baran, B.; Humke, E. W.; Rohatgi, R.; Niewiadomski, P.
10.1101/2021.09.27.461918 — cell biology — Posted on 2021-09-28
460 Visualization of bacterial type 3 secretion system components down to the molecular level by MINFLUX nanoscopy
Carsten, A.; Rudolph, M.; Weihs, T.; Schmidt, R.; Wurm, C. A.; Diepold, A.; Failla, A. V.; Wolters, M.; Aepfelbacher, M.
10.1101/2021.09.27.461991 — microbiology — Posted on 2021-09-28
461 Lomitapide, a cholesterol-lowering drug, is an anticancer agent that induces autophagic cell death via inhibiting mTOR
Lee, B.; Park, S. J.; Lee, S.; Lee, J.; Lee, E.; Yoo, E.-S.; Chung, W.-S.; Sohn, J.-W.; Oh, B.-C.; Kim, S.
10.1101/2021.09.27.461902 — cancer biology — Posted on 2021-09-28
462 Sex differences and risk factors for bleeding in Alagille syndrome
Hankeova, S.; Van Hul, N.; Laznovsky, J.; Mangold, K.; Hensens, N.; Verhoef, E.; Zikmund, T.; Dawit, F.; Kavkova, M.; Salplachta, J.; Sjoqvist, M.; Johansson, B.; Hassan, M.; Fredriksson, L.; Bryja, V.; Lendahl, U.; Jheon, A.; Alten, F.; Fahnehjelm, K. T.; Fischler, B.; Kaiser, J.; Andersson, E. R.
10.1101/2021.04.13.439679 — developmental biology — Posted on 2021-09-28
466 Multiple metals influence distinct properties of the Arabidopsis circadian clock
Hargreaves, J. K.; Oakenfull, R.; Davis, A.; Pullen, F.; Knight, M.; Pitchford, J.; Davis, S.
10.1101/2021.09.27.462026 — plant biology — Posted on 2021-09-27
470 Opposing roles of blood-borne monocytes and tissue-resident macrophages in limbal stem cell damage after ocular injury
Zhou, C.; Lei, F.; Mittermaier, M.; Ksander, B.; Dana, R.; Dohlman, C. H.; Vavvas, D. G.; Chodosh, J.; Paschalis, E. I.
10.1101/2021.07.25.453707 — immunology — Posted on 2021-09-27
471 Sensory evidence accumulation using optic flow in a naturalistic navigation task
Alefantis, P.; Lakshminarasimhan, K. J.; Avilla, E.; Noel, J.-P.; Pitkow, X.; Angelaki, D.
10.1101/2021.04.26.441532 — neuroscience — Posted on 2021-09-27
472 Plant-based biosensors for detecting CRISPR-mediated genome engineering
Yuan, G.; Hassan, M. M.; Yao, T.; Lu, H.; Vergara, M. M.; Labbe, J.; Muchero, W.; Pan, C.; Chen, J.-G.; Tuskan, G. A.; Qi, Y.; Abraham, P. E.; Yang, X.
10.1101/2021.09.27.461852 — plant biology — Posted on 2021-09-27
474 Characterizing SERCA function in murine skeletal muscles after 35-37 days of spaceflight
Braun, J. L.; Geromella, M. S.; Hamstra, S. I.; Messner, H. N.; Fajardo, V. A.
10.1101/2021.09.27.462048 — physiology — Posted on 2021-09-27
475 HSD11β1 promotes EMT-mediated breast cancer metastasis
Nakayama, J.; Ishikawa, T.; Nishimura, T.; Yamanaka, S.; Gotoh, N.; Yamauchi, C.; Onishi, T.; Soga, T.; Fujii, S.; Makinoshima, H.
10.1101/2021.09.27.461934 — cancer biology — Posted on 2021-09-27
479 The bacterial magnesium transporter MgtA reveals highly selective interaction with specific cardiolipin species
Weikum, J.; Vandyck, J.; Subramani, S.; Klebl, D. P.; Storflor, M.; muench, s. P.; Abel, S.; Sobott, F.; Morth, J. P.
10.1101/2021.09.27.462033 — biochemistry — Posted on 2021-09-27
480 Intergenerational hormesis is regulated by heritable 18S rRNA methylation
Liberman, N.; Gerashchenko, M.; Boulias, K.; MacWhinnie, F.; Ying, K.; Taylor, A. F.; Al Haddad, J.; Shibuya, H.; Roach, L.; Dong, A.; Gladyshev, V. N.; Greer, E. L.
10.1101/2021.09.27.461965 — genetics — Posted on 2021-09-27
487 BMP7 increases UCP1-dependent and independent thermogenesis with a unique gene expression program in human neck area derived adipocytes
Shaw, A.; Toth B, B.; Arianti, R.; Csomos, I.; Poliska, S.; Vamos, A.; Bacso, Z.; Gyory, F.; Fesüs, L.; Kristof, E.
10.1101/2021.09.27.461971 — cell biology — Posted on 2021-09-27
489 Growing Glycans in Rosetta: Accurate de novo glycan modeling, density fitting, and rational sequon design
Adolf-Bryfogle, J.; Labonte, J. W.; Kraft, J. C.; Shapavolov, M.; Raemisch, S.; Lutteke, T.; Dimaio, F.; Bahl, C. D.; Pallesen, J.; King, N. P.; Gray, J. J.; Kulp, D. W.; Schief, W. R.
10.1101/2021.09.27.462000 — molecular biology — Posted on 2021-09-27
490 Response of Endozoicomonas montiporae to heat stress and coral host lysates
Chan, Y.; Chen, C.-Y.; Lu, C.-Y.; Tu, Y.-C.; Tandon, K.; Shikina, S.; Tang, S.-L.
10.1101/2021.09.27.461970 — microbiology — Posted on 2021-09-27
491 HIV-1 hijacks the cell extracellular matrix to spread collectively and efficiently between T lymphocytes
Inizan, C.; Caillet, M.; Desrames, A.; Bomme, P.; MALLET, A.; Bourdic, K.; Lambotte, O.; Boufassa, F.; Mesel-Lemoine, M.; Tangy, F.; Pancino, G.; Mouquet, H.; Lagache, t.; Dufour, A. C.; Olivo-Marin, J.-C.; Rey, F. A.; Saez-Cirion, A.; Thoulouze, M.-I.
10.1101/2021.09.27.461933 — microbiology — Posted on 2021-09-27
494 Pre-mRNA Splicing Factor U2AF2 Recognizes Distinct Conformations of Nucleotide Variants at the Center of the pre-mRNA Splice Site Signal
Glasser, E.; Maji, D.; Biancon, G.; Keedakkatt Puthenpeedikakkal, A. M.; Cavender, C.; Tebaldi, T.; Pulvino, M. J.; Jenkins, J. L.; Mathews, D. H.; Halene, S.; Kielkopf, C. L.
10.1101/2021.09.27.462007 — biophysics — Posted on 2021-09-27
495 Green light perception paved the way for the diversification of GAF domain photoreceptors
Priyadarshini, N.; Steube, N.; Wiens, D.; Narikawa, R.; Wilde, A.; Hochberg, G. K. A.; Enomoto, G.
10.1101/2021.09.27.462012 — biochemistry — Posted on 2021-09-27
498 DeepNull: Modeling non-linear covariate effects improves phenotype prediction and association power
Mccaw, Z. R.; Colthurst, T.; Yun, T.; Furlotte, N. A.; Carroll, A.; Alipanahi, B.; McLean, C.; Hormozdiari, F.
10.1101/2021.05.26.445783 — genetics — Posted on 2021-09-27
502 Visualization of bacterial type 3 secretion system components down the molecular level by MINFLUX nanoscopy
Carsten, A.; Rudolph, M.; Weihs, T.; Schmidt, R.; Wurm, C. A.; Diepold, A.; Failla, A. V.; Wolters, M.; Aepfelbacher, M.
10.1101/2021.09.27.461991 — microbiology — Posted on 2021-09-27
503 The DarTG toxin-antitoxin system provides phage defense by ADP-ribosylating viral DNA
LeRoux, M.; Srikant, S.; Littlehale, M. L.; Teodoro, G.; Doron, S.; Badiee, M.; Leung, A.; Sorek, R.; Laub, M. T.
10.1101/2021.09.27.462013 — microbiology — Posted on 2021-09-27
504 Ecological stochasticity and phage induction diversify bacterioplankton communities at the microscale
Szabo, R. E.; Pontrelli, S.; Grilli, J.; Schwartzman, J. A.; Pollak, S.; Sauer, U.; Cordero, O. X.
10.1101/2021.09.27.461956 — microbiology — Posted on 2021-09-27
505 Viral replication in human macrophages enhances an inflammatory cascade and interferon driven chronic COVID-19 in humanized mice.
Sefik, E.; Qu, R.; Kaffe, E.; Zhao, J.; Junqueira, C.; Mirza, H.; Brewer, R.; Han, A.; Steach, H.; Israelow, B.; Chen, Y. G.; Halene, S.; Iwasaki, A.; Meffre, E.; Nussenzweig, M.; Lieberman, J.; Wilen, C. B.; Kluger, Y.; Flavell, R. A.
10.1101/2021.09.27.461948 — immunology — Posted on 2021-09-27
506 Brain fatty acid binding protein exhibits non-preferential and mutation-resistant binding towards fatty acids
Bodnariuc, I.; Lenz, S.; Renaud-Young, M.; Shandro, T. M.; Ishida, H.; Vogel, H. J.; MacCallum, J. L.
10.1101/2021.09.23.461245 — biophysics — Posted on 2021-09-27
507 AxonDeep: Automated Optic Nerve Axon Segmentation in Mice with Deep Learning.
Deng, W.; Hedberg-Buenz, A.; Soukup, D. A.; Taghizadeh, S.; Wang, K.; Anderson, M. G.; Garvin, M. K.
10.1101/2021.05.21.445196 — bioengineering — Posted on 2021-09-27
509 Comparison of breeding strategies for the creation of a synthetic pig line
Ganteil, A.; Pook, T.; Rodriguez-Ramilo, S. T.; Ligonesche, B.; Larzul, C.
10.1101/2021.09.22.461330 — genetics — Posted on 2021-09-27
511 Role of the mobilome in the global dissemination of the carbapenem resistance gene blaNDM
Acman, M.; Wang, R.; van Dorp, L.; Shaw, L. P.; Wang, Q.; Luhmann, N.; Yuyao, Y.; Sun, S.; Chen, H.; Wang, H.; Balloux, F.
10.1101/2021.01.14.426698 — microbiology — Posted on 2021-09-27
512 Role of type I interferon signaling and microglia in the abnormal long term potentiation and object place recognition deficits of male mice with a mutation of the Tuberous Sclerosis 2 gene
Lopez-Aranda, M. F.; Boxx, G. M.; Phan, M.; Bach, K.; Mandanas, R.; Herrera, I.; Taloma, S.; Thadani, C.; Lu, O.; Bui, R.; Liu, S.; Li, N.; Zhou, Y.; Silva, A. J.
10.1101/2021.09.27.461827 — neuroscience — Posted on 2021-09-27
513 Neural oscillation coupling selectively predicts speech reception in young children with Autism Spectrum Disorder
Wang, X.; Delgado Saa, J. F.; Marchesotti, S.; Kojovic, N.; Sperdin, H. F.; Rihs, T. A.; Schaer, M.; Giraud, A.-L.
10.1101/2021.09.27.461214 — neuroscience — Posted on 2021-09-27
516 A Hierarchical Process Model Links Behavioral Aging and Lifespan in C. elegans
Oswal, N.; Martin, O. M. F.; Stroustrup, S.; Matusiak Bruckner, M. A.; Stroustrup, N.
10.1101/2021.03.31.437415 — systems biology — Posted on 2021-09-27
518 LADON, a natural antisense transcript of NODAL, promotes the acquisition of an invasive behaviour in melanoma cells.
Dutriaux, A.; Diazzi, S.; Caburet, S.; Bresesti, C.; Hardouin, S.; Deshayes, F.; Collignon, J.; Flagiello, D.
10.1101/2020.04.09.032375 — cancer biology — Posted on 2021-09-27
519 Non-invasive imaging of gene expression and protein secretion dynamics in living mice uncovers ectopic prothrombin expression as driver of thrombosis in cancer
Nourse, J.; Tokalov, S.; Khokhar, S.; Khan, E.; Schott, L. K.; Hinz, L.; Eder, L.; Arnold-Schild, D.; Lackner, K. J.; Ten Cate, H.; Probst, H. C.; Danckwardt, S.
10.1101/2021.07.08.451623 — cancer biology — Posted on 2021-09-27
525 The transposable element-rich genome of the cereal pest Sitophilus oryzae
Parisot, N.; Vargas-Chavez, C.; Goubert, C.; Baa-Puyoulet, P.; Balmand, S.; Beranger, L.; Blanc, C.; Bonnamour, A.; Boulesteix, M.; Burlet, N.; Calevro, F.; Callaerts, P.; Chancy, T.; Charles, H.; Colella, S.; Da Silva Barbosa, A.; Dell'Aglio, E.; Di Genova, A.; Febvay, G.; Gabaldon, T.; Galvao Ferrarini, M.; Gerber, A.; Gillet, B.; Hubley, R.; Hughes, S.; Jacquin-Joly, E.; Maire, J.; Marcet-Houben, M.; Masson, F.; Meslin, C.; Montagne, N.; Moya, A.; Ribeiro de Vasconcelos, A. T.; Richard, G.; Rosen, J.; Sagot, M.-F.; Smit, A. F.; Storer, J.; Vincent-Monegat, C.; Vallier, A.; Vigneron, A.; Zai
10.1101/2021.03.03.408021 — genomics — Posted on 2021-09-27
526 Forkhead transcription factor FKH-8 is a master regulator of primary cilia in C. elegans
Brocal-Ruiz, R.; Esteve-Serrano, A.; Mora-Martinez, C.; Swoboda, P.; Tena, J.; Flames, N.
10.1101/2021.09.14.460205 — developmental biology — Posted on 2021-09-27
527 The novel anti-CRISPR AcrIIA22 relieves DNA torsion in target plasmids and impairs SpyCas9 activity
Forsberg, K. J.; Schmidtke, D. T.; Werther, R.; Uribe, R. V.; Hausman, D.; Sommer, M. O. A.; Stoddard, B. L.; Kaiser, B. K.; Malik, H. S.
10.1101/2020.09.28.317578 — microbiology — Posted on 2021-09-27
529 Fast resupply of synaptic vesicles requires Synaptotagmin-3
Weingarten, D. J.; Shrestha, A.; Kissiwaa, S. A.; Spruston, E.; Jackman, S. L.
10.1101/2021.09.27.462028 — neuroscience — Posted on 2021-09-27
533 Energy status-promoted growth and development of Arabidopsis require copper deficiency response transcriptional regulator SPL7
Schulten, A.; Pietzenuk, B.; Quintana, J.; Krause, M.; Feil, R.; Romera-Branchat, M.; Wahl, V.; Severing, E.; Coupland, G.; Kraemer, U.
10.1101/2021.09.17.460807 — plant biology — Posted on 2021-09-27
534 Regional and clonal T cell dynamics at single cell resolution in immune checkpoint blockade
Pai, J. A.; Chow, A.; Sauter, J.; Mattar, M.; Rizvi, H.; Woo, H. J.; Shah, N.; Uddin, F.; Quintanal-Villalonga, A.; Chan, J. M.; Manoj, P.; Allaj, V.; Baine, M.; Chaft, J. E.; Plodkowski, A. J.; Won, H.; Wells, D.; Donoghue, M. T. A.; de Stanchina, E.; Sen, T.; Wolchok, J. D.; Houck-Loomis, B.; Merghoub, T.; Rudin, C. M.; Satpathy, A. T.; Hellmann, M. D.
10.1101/2021.09.27.461389 — immunology — Posted on 2021-09-27
535 In-silico analysis: common biomarkers of NDs
Sarkar, D.; Chakraborty, S.; Maiti, T.; Bhowmick, S.
10.1101/2021.09.25.461779 — neuroscience — Posted on 2021-09-27
537 CDK1 and HSP90AA1 appears as novel regulatory gene in Non-Small Cell Lung Cancer: A Bioinformatics Approach
Bhattacharyya, N.; Gupta, S.; Sharma, S.; Soni, A.; Bhattacharyya, M.; Mukherjee, A.; Malik, Z.; Ray, A. K.
10.1101/2021.09.26.461854 — systems biology — Posted on 2021-09-27
539 Systematic Transmission Electron Microscopy-Based Identification of Cellular Degradation Machinery
Neikirk, K.; Vue, Z.; Katti, P.; Shao, J.; Christensen, T. A.; Garza Lopez, E.; Marshall, A.; Palavicino-Maggio, C.; Ponce, J.; Alghanem, A.; Vang, L.; Beasley, H.; Rodman, T.; Mungai, M.; Correia, M.; Exil, V.; Murray, S.; Salisbury, J. L.; Glancy, B.; Pereira, R. O.; Abel, E. D.; Hinton, A.
10.1101/2021.09.26.461841 — biophysics — Posted on 2021-09-27
541 SARS-CoV-2 spike-specific memory B cells express markers of durable immunity after non-severe COVID-19 but not after severe disease
Reyes, R.; Clarke, K.; Gonzales, S. J.; Cantwell, A. M.; Garza, R.; Catano, G.; Tragus, R. E.; Patterson, T. F.; Bol, S.; Bunnik, E. M.
10.1101/2021.09.24.461732 — immunology — Posted on 2021-09-27
542 Spike independent replication of human coronavirus in bat cells
Linster, M.; Mah, M. G.; Low, D. H.; Yan, Z.; Jayakumar, J.; Samsudin, F.; Wong, F. Y.; Bond, P. J.; Mendenhall, I. H.; Su, Y. C.; Smith, G. J.
10.1101/2021.09.18.460924 — microbiology — Posted on 2021-09-27
543 The role of complex IV activity in the axonal response of mitochondria to demyelination in experimental disease models of multiple sclerosis
Licht-Mayer, S.; Campbell, G. R.; Metha, A. R.; McGill, K.; Symonds, A.; Al-Azki, S.; Pryce, G.; Zandee, S.; Zhao, C.; Kipp, M.; Smith, K. J.; Baker, D.; Altman, D.; Anderton, S. M.; Kap, Y. S.; Laman, J. D.; t'Hart, B. A.; Rodriguez, M.; Franklin, R. J. M.; Chandran, S.; Lassmann, H.; Trapp, B. D.; Mahad, D. J.
10.1101/2021.09.27.461926 — neuroscience — Posted on 2021-09-27
544 Balance between protective and pathogenic immune responses to pneumonia in the neonatal lung enforced by gut microbiota.
Stevens, J.; Steinmeyer, S.; Bonfield, M.; Wang, T.; Gray, J.; Lewkowich, I.; Xu, Y.; Du, Y.; Guo, M.; Wynn, J. L.; Zacharias, W.; Salomonis, N.; Miller, L.; Chougnet, C.; Hartigan O'Connor, D.; Deshmukh, H.
10.1101/2021.09.27.461705 — immunology — Posted on 2021-09-27
548 Phostensin Enables Lymphocyte Integrin Activation and Population of Peripheral Lymphoid Organs
Lee, H.; Sun, H.; Lagarrigue, F.; Fox, J. W.; Sherman, N. E.; Gingras, A.; Ginsberg, M.
10.1101/2021.09.24.461584 — immunology — Posted on 2021-09-27
550 Neural oscillation coupling selectively predicts speech reception in young children with Autism Spectrum Disorder
Wang, X.; Delgado Saa, J. F.; Marchesotti, S.; Kojovic, N.; Sperdin, H. F.; Rihs, T. A.; Schaer, M.; Giraud, A.-L.
10.1101/2021.09.27.461214 — neuroscience — Posted on 2021-09-27
555 Different plasticity of bud outgrowth at cauline and rosette nodes in Arabidopsis thaliana
Fichtner, F.; Barbier, F. F.; Kerr, S. C.; Dudley, C.; Cubas, P.; Turnbull, C.; Brewer, P. B.; Beveridge, C. A.
10.1101/2021.09.26.461886 — plant biology — Posted on 2021-09-27
556 Bioorthogonally Cross-Linked Hyaluronan-Laminin Hydrogels for 3D Neuronal Cell Culture and Biofabrication
Jury, M.; Matthiesen, I.; Rasti Boroojeni, F.; Ludwig, S.; Civitelli, L.; Winkler, T. E.; Selegard, R.; Herland, A.; Aili, D.
10.1101/2021.09.27.461549 — bioengineering — Posted on 2021-09-27
557 Molecular insights into the inhibition of plasmepsins by HIV-1 protease inhibitors: Implications for antimalarial drug discovery
Mishra, V.; Rathore, I.; Deshmukh, A.; Patankar, S.; Gustchina, A.; Wlodawer, A.; Yada, R. Y.; Bhaumik, P.
10.1101/2021.09.27.461917 — biochemistry — Posted on 2021-09-27
559 Genome assembly of the tayra (Eira barbara, Mustelidae) and comparative genomic analysis reveal adaptive genetic variation in the subfamily Guloninae
Derezanin, L.; Blazyte, A.; Dobrynin, P.; Duchene, D. A.; Grau, J. H.; Jeon, S.; Kliver, S.; Koepfli, K.-P.; Meneghini, D.; Preick, M.; Tomarovsky, A.; Totikov, A.; Fickel, J.; Förster, D. W.
10.1101/2021.09.27.461651 — evolutionary biology — Posted on 2021-09-27
561 Prospective isolation of mouse and human hematopoietic stem cells using Plexin domain containing 2
Tanaka, Y.; Kubota, Y.; Lieberam, I.; Barlow, J. L.; Bramley, J. W.; Sakuma, C.; Shibata, T.; Nakagawa, M.; Kurosawa, Y.; Maruyama, T.; Okumura, C. J.; Akuta, T.; Kent, D. G.; Jessell, T. M.; Goyama, S.; Kimura, S.; Kitamura, T.
10.1101/2021.09.27.461900 — cell biology — Posted on 2021-09-27
566 Tuft cell-produced cysteinyl leukotrienes and IL-25 synergistically drivelung type 2 inflammation
Ualiyeva, S.; Lemire, E. R.; Boyd, A.; Wong, C.; Lai, J.; Liu, T.; Matsumoto, I.; Barrett, N. A.; Boyce, J. A.; Haber, A. L.; Bankova, L.
10.1101/2021.09.26.461888 — immunology — Posted on 2021-09-27
568 GABAB receptor/HCN channel complexes in VTA dopamine neurons limit synaptic inhibition and prevent anxiety-like behavior
Bettler, B.; Rizzi, G.; Fritzius, T.; Perez-Garci, E.; Porcu, A.; Besseyrias, V.; Gassmann, M.; Tan, K. R.
10.1101/2021.09.27.461912 — neuroscience — Posted on 2021-09-27
570 scoMorphoFISH: A Deep-Learning enabled toolbox for single-cell single-mRNA quantification and correlative (ultra-)morphometry
Siegerist, F.; Hay, E.; Dikou, J. S.; Buescher, A.; Oh, J.; Ribback, S.; Zimmermann, U.; Braesen, J. H.; Lenoir, O.; Endlich, K.; Tharaux, P.-L.; Endlich, N.
10.1101/2021.09.27.461916 — pathology — Posted on 2021-09-27
572 Lomitapide, a cholesterol-lowering drug, is an anticancer agent that induces autophagic cell death via inhibiting mTOR
Lee, B.; Park, S. J.; Lee, S.; Lee, J.; Lee, E. B.; Yoo, E.-S.; Chung, W.-S.; Sohn, J.-W.; Oh, B.-C.; Kim, S.
10.1101/2021.09.27.461902 — cancer biology — Posted on 2021-09-27
582 Using trait data improves correlation between environment and community data only if abundances are considered
Lengyel, A.; Sandor, B.; Berki, B.; Csecserits, A.; Gyalus, A.; Lhotsky, B.; Onodi, G.; Redei, T.; Botta-Dukat, Z.
10.1101/2021.09.27.461896 — ecology — Posted on 2021-09-27
583 Inhibition of Kallikrein-related peptidases 7 restrains pancreatic tumor growth through induction of ferroptosis
Tan, X.; Wang, Y.; Xiang, F.; Deng, H.; Leng, S.; Zhao, D.; Chen, Y.; Xie, D.; Li, Q.; Cao, C.; Zheng, W.; Liu, W.; Liu, X.; Zheng, J.
10.1101/2021.09.27.461898 — molecular biology — Posted on 2021-09-27
585 Transient dendritic cell activation diversifies the T cell response to acute infection
Hiam-Galvez, K. J.; Debarge, R.; Lareau, C. A.; Cho, N. W.; Yee, J. L.; Okholm, T. L. H.; Spitzer, M. H.
10.1101/2021.09.26.461821 — immunology — Posted on 2021-09-27
588 Minos: variant adjudication and joint genotyping of cohorts of bacterial genomes
Hunt, M.; Letcher, B.; Malone, K. M.; Nguyen, G.; Hall, M. B.; Colquhoun, R. M.; Lima, L.; Schatz, M.; Ramakrishnan, S.; The CRyPTIC Consortium, ; Iqbal, Z.
10.1101/2021.09.15.460475 — bioinformatics — Posted on 2021-09-27
589 A computational exploration of resilience and evolvability of protein-protein interaction networks
Klein, B.; Holmer, L.; Smith, K. M.; Johnson, M.; Swain, A.; Stolp, L.; Teufel, A. I.; Kleppe, A. S.
10.1101/2020.07.02.184325 — systems biology — Posted on 2021-09-27
590 A locus conferring tolerance to Theileria infection in African cattle
Wragg, D.; Cook, E. A. J.; Latre de Late, P.; Sitt, T.; Hemmink, J. D.; Chepkwony, M.; Njeru, R.; Poole, E. J.; Powell, J.; Paxton, E.; Callaby, R.; Talenti, A.; Miyunga, A. A.; Ndambuki, G.; Mwaura, S.; Auty, H.; Matika, O.; Hassan, M. A.; Marshall, K.; Connelley, T. K.; Morrison, L.; Bronsvoort, B. M.; Morrison, W. I.; Toye, P.; Prendergast, J. G.
10.1101/2021.07.26.453771 — genetics — Posted on 2021-09-27
598 Innate immune signaling drives late cardiac toxicity following DNA damaging cancer therapies
Shamseddine, A.; Patel, S.; Chavez, V.; Adnan, M.; Di Bona, M.; Li, J.; Dang, C. T.; Ramanathan, L. V.; Oeffinger, K. C.; Liu, J. E.; Steingart, R. M.; Piersigilli, A.; Socci, N. D.; Chan, A. T.; Yu, A. F.; Bakhoum, S. F.; Schmitt, A. M.
10.1101/2021.09.26.461865 — immunology — Posted on 2021-09-26
600 KLC4 shapes axon arbors during development and mediates adult behavior
Haynes, E. M.; He, J.; Jean-Pierre, M.; Eliceiri, K. W.; Huisken, J.; Halloran, M.
10.1101/2021.09.26.461872 — neuroscience — Posted on 2021-09-26
602 An innate immune activation state prior to vaccination predicts responsiveness to multiple vaccines
Fourati, S.; Tomalin, L. E.; Mule, M. P.; Chawla, D. G.; Gerritsen, B.; Rychkov, D.; Henrich, E.; Miller, H. E.; Hagan, T.; Diray-Arce, J.; Dunn, P.; The Human Immunology Project Consortium (HIPC), ; Levy, O.; Gottardo, R.; Sarwal, M.; Tsang, J.; Suarez-Farinas, M.; Pulendran, B.; Sekaly, R.-P.; Kleinstein, S. H.
10.1101/2021.09.26.461847 — systems biology — Posted on 2021-09-26
605 Classification, Using Field Potential Images, of Pacemaker Micro-coordination in the Mouse Intestine
Iwata, N.; Takai, C.; Mochizuki, N.; Yamauchi, M.; Kaji, N.; Kasahara, Y.; Nakayama, S.
10.1101/2021.05.29.446256 — physiology — Posted on 2021-09-26
606 Electrodeformation of White Blood Cells Enriched with Gold Nanoparticles
Hallfors, N. G.; Teo, J. M.; Bertone, P.; Joshi, C.; Orozaliev, A.; Martin, M. N.; Isakovic, A. F.
10.1101/2021.09.25.461820 — biophysics — Posted on 2021-09-26
607 Atomic-Resolution Prediction of Degrader-mediated Ternary Complex Structures by Combining Molecular Simulations with Hydrogen Deuterium Exchange
Dixon, T.; MacPherson, D.; Mostofian, B.; Dauzhenka, T.; Lotz, S.; McGee, D.; Shechter, S.; Shrestha, U.; Wiewiora, R.; McDargh, Z. A.; Pei, F.; Pal, R.; Ribeiro, J. V.; Wilkerson, T.; Sachdeva, V.; Gao, N.; Jain, S.; Sparks, S.; Li, Y.; Vinitsky, A.; Razavi, A. M.; Kolossvary, I.; Imbriglio, J.; Evdokimov, A.; Bergeron, L.; Dickson, A.; Xu, H.; Sherman, W.; Izaguirre, J. A.
10.1101/2021.09.26.461830 — biophysics — Posted on 2021-09-26
608 Spontaneous nucleation and fast aggregate-dependent proliferation of α-synuclein aggregates within liquid condensates at physiological pH
Dada, S. T.; Hardenberg, M. C.; Mrugalla, L. K.; McKeon, M. O.; Klimont, E.; Michaels, T. T. C.; Vendruscolo, M.
10.1101/2021.09.26.461836 — biophysics — Posted on 2021-09-26
613 Comparative genomics reveals electron transfer and syntrophic mechanisms differentiating methanotrophic and methanogenic archaea
Chadwick, G. L.; Skennerton, C. T.; Laso-Perez, R.; Leu, A. O.; Speth, D. R.; Yu, H.; Morgan-Lang, C.; Hatzenpichler, R.; Goudeau, D.; Malmstrom, R.; Brazelton, W. J.; Woyke, T.; Hallam, S. J.; Tyson, G. W.; Wegener, G.; Boetius, A.; Orphan, V. J.
10.1101/2021.09.25.461819 — microbiology — Posted on 2021-09-26
614 Flygenvectors: The spatial and temporal structure of neural activity across the fly brain
Schaffer, E. S.; Mishra, N.; Whiteway, M. R.; Li, W.; Vancura, M. B.; Freedman, J.; Patel, K. B.; Voleti, V.; Paninski, L.; Hillman, E. M. C.; Abbott, L.; Axel, R.
10.1101/2021.09.25.461804 — neuroscience — Posted on 2021-09-26
616 Backward masking in mice requires visual cortex
Gale, S.; Strawder, C.; Bennett, C.; Mihalas, S.; Koch, C.; Olsen, S. R.
10.1101/2021.09.26.461573 — neuroscience — Posted on 2021-09-26
617 Computing personalized brain functional networks from fMRI using self-supervised deep learning
Li, H.; Dhivya, S.; Cui, Z.; Zhuo, C.; Gur, R. E.; Gur, R. C.; Oathes, D. J.; Davatzikos, C.; Satterthwaite, T. D.; Fan, Y.
10.1101/2021.09.25.461829 — neuroscience — Posted on 2021-09-26
619 The Impact of Body Mass Index on Physical Activity and Cardiac Workload
Bloom, M. J.; Brown, L. M.; Jost, S. R.; Lang, A. S. I. D.; Mankin, N. V.; Mast, Z. W.; McMahan, E. R.; Merheb, J. A.; Nelson, P. P.; Nnaji, J. C.; Valderrama, E. F.
10.1101/2021.09.26.461877 — physiology — Posted on 2021-09-26
620 Maximally predictive ensemble dynamics from data
Costa, A. C.; Ahamed, T.; Jordan, D.; Stephens, G. J.
10.1101/2021.05.26.445816 — biophysics — Posted on 2021-09-26
621 A structural biology community assessment of AlphaFold 2 applications
Akdel, M.; Pires, D. E.; Porta-Pardo, E.; Janes, J.; Zalevsky, A. O.; Meszaros, B.; Bryant, P.; Good, L. L.; Laskowski, R. A.; Pozzati, G.; Shenoy, A.; Zhu, W.; Kundrotas, P.; Ruiz-Serra, V.; Rodrigues, C. H.; Dunham, A. S.; Burke, D.; Borkakoti, N.; Velankar, S.; Frost, A.; Lindorff-Larsen, K.; Valencia, A.; Ovchinnikov, S.; Durairaj, J.; Ascher, D. B.; Thornton, J. M.; Davey, N. E.; Stein, A.; Elofsson, A.; Croll, T. I.; Beltrao, P.
10.1101/2021.09.26.461876 — biophysics — Posted on 2021-09-26
627 Optogenetic perturbations of RNA expression in tissue space
Legnini, I.; Emmenegger, L.; Wurmus, R.; Zappulo, A.; Oliveras Martinez, A.; Cerda Jara, C.; Boltengagen, A.; Hessler, T.; Mastrobuoni, G.; Rybak-Wolf, A.; Kempa, S.; Zinzen, R. P.; Woehler, A.; Rajewsky, N.
10.1101/2021.09.26.461850 — bioengineering — Posted on 2021-09-26
630 PplD is a de-N-acetylase of the cell wall linkage unit of streptococcal rhamnopolysaccharides
Rush, J. S.; Parajuli, P.; Ruda, A.; Li, J.; Pohane, A. A.; Zamakhaeva, S.; Rahman, M. M.; Chang, J. C.; Gogos, A.; Kenner, C. W.; Lambeau, G.; Federle, M. J.; Korotkov, K. V.; Widmalm, G.; Korotkova, N.
10.1101/2021.09.23.461590 — microbiology — Posted on 2021-09-26
633 Extrasynaptic signaling enables an asymmetric juvenile motor circuit to produce a symmetric gait
Lu, Y.; Ahamed, T.; Mulcahy, B.; Witvliet, D.; Guan, S. A.; Hung, W.; Meng, J.; Wen, Q.; Samuel, A.; Zhen, M.
10.1101/2021.09.21.461278 — neuroscience — Posted on 2021-09-26
634 Human metapneumovirus P protein independently drives phase separation and recruits N protein to liquid-like inclusion bodies
Boggs, K. B.; Cifuentes-Munoz, N.; Edmonds, K.; El Najjar, F.; Ossandon, C.; Roe, M.; Moncman, C. L.; Creamer, T. P.; Dutch, R. E.
10.1101/2021.09.24.461765 — microbiology — Posted on 2021-09-26
637 Lactoferricins access the cytosol of Escherichia coli within few seconds
Semeraro, E. F.; Marx, L.; Mandl, J.; Letofsky-Papst, I.; Mayrhofer, C.; Frewein, M. P. K.; Scott, H. L.; Prevost, S.; Bergler, H.; Lohner, K.; Pabst, G.
10.1101/2021.09.24.461681 — biophysics — Posted on 2021-09-26
641 GLOBAL PATTERNS OF PLUMAGE COLOUR EVOLUTION IN ISLAND-LIVING PASSERIFORM BIRDS
Mahoney, S. M.; Oud, M. D.; Pageau, C.; Argollo de Menezes, M.; Smith, N.; Briskie, J. V.; Reudink, M. W.
10.1101/2021.09.20.461154 — ecology — Posted on 2021-09-26
642 Cryo-EM structure of a single-chain β1-adrenoceptor - AmpC β-lactamase fusion protein
Collu, G.; Mohammed, I.; Lafita, A.; Bierig, T.; Poghosyan, E.; Bliven, S.; Benoit, R. M.
10.1101/2021.09.25.461805 — molecular biology — Posted on 2021-09-26
643 Label-free Raman microspectroscopy for identifying virocells
Monsees, I.; Turzynski, V.; Esser, S. P.; Soares, A.; Timmermann, L. I.; Weidenbach, K.; Banas, J.; Kloster, M.; Beszteri, B.; Schmitz, R. A.; Probst, A. J.
10.1101/2021.09.22.461451 — microbiology — Posted on 2021-09-26
645 T cells modulate the microglial response to brain ischemia
Benakis, C.; Simats, A.; Tritschler, S.; Heindl, S.; Besson-Girard, S.; Llovera, G.; Pinkham, K.; Kolz, A.; Theis, F. J.; Gökce, O.; Peters, A.; Liesz, A.
10.1101/2021.09.23.461546 — immunology — Posted on 2021-09-26
646 The Fe-S cluster assembly factors NFU4 and NFU5 are primarily required for protein lipoylation in mitochondria
Przybyla-Toscano, J.; Maclean, A. E.; Franceschetti, M.; Liebsch, D.; Vignols, F.; Keech, O.; Rouhier, N.; Balk, J.
10.1101/2021.09.24.461724 — plant biology — Posted on 2021-09-26
650 Uterus-specific transcriptional regulation underlies eggshell pigment production in Japanese quail
Ishishita, S.; Kitahara, S.; Takahashi, M.; Iwasaki, S.; Tatsumoto, S.; Hara, I.; Kaneko, Y.; Kinoshita, K.; Yamaguchi, K.; Harada, A.; Ohmori, Y.; Ohkawa, Y.; Go, Y.; Shigenobu, S.; Matsuda, Y.; Suzuki, T.
10.1101/2021.09.15.460419 — genetics — Posted on 2021-09-26
652 The PhoPQ two-component system promotes carbapenem tolerance in Enterobacterales.
Murtha, A. N.; Kazi, M. I.; Schargel, R. D.; Cross, T.; Fihn, C.; Carlson, E. E.; Boll, J. M.; Dörr, T.
10.1101/2021.09.25.461800 — microbiology — Posted on 2021-09-26
659 RIG-I uses its intrinsically disordered CARDs-Helicase linker in RNA proofreading functions
Schweibenz, B. D.; Devarkar, S. C.; Solotchi, M.; Zheng, J.; Pascal, B. D.; Griffin, P.; Patel, S. S.
10.1101/2021.09.23.461459 — biochemistry — Posted on 2021-09-25
662 Spinal reconsolidation engages non-ionotropic NMDA receptor signaling to reverse pain hypersensitivity
D'Souza, A. J.; Rodriguez-Hernandez, D.; Zhang, H.; He, D. Y.; Zain, M.; Fung, S.; Bennett, L. A.; Bonin, R. P.
10.1101/2021.09.08.458120 — neuroscience — Posted on 2021-09-25
664 Depletion of nuclear pore protein NUP210 suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response
Amin, R.; Shukla, A.; Zhu, J. J.; Kim, S.; Wang, P.; Tian, S. Z.; Tran, A. D.; Paul, D.; Cappell, S. D.; Burkett, S.; Liu, H.; Lee, M. P.; Kruhlak, M. J.; Dwyer, J. E.; Simpson, R. M.; Hager, G. L.; Ruan, Y.; Hunter, K. W.
10.1101/2020.02.05.936518 — cancer biology — Posted on 2021-09-25
668 Recruitment of CTCF to an Fto enhancer is responsible for transgenerational inheritance of obesity
Jung, Y. H.; Wang, H.-L. V.; Ruiz, D.; Grandi, F. C.; Bixler, B. J.; Linsenbaum, H.; Xiang, J.-F.; Shafik, A. M.; Jin, P.; Corces, M. R.; Corces, V. G.
10.1101/2020.11.20.391672 — genomics — Posted on 2021-09-25
672 Post-trauma behavioral phenotype predicts vulnerability to fear relapse after extinction
Demars, F.; Todorova, R.; Makdah, G.; Forestier, A.; Krebs, M.-O.; Godsil, B. P.; Jay, T. M.; Wiener, S. I.; Pompili, M. N.
10.1101/2021.09.25.461769 — neuroscience — Posted on 2021-09-25
678 Transcriptome-wide association and prediction for carotenoids and tocochromanols in fresh sweet corn kernels
Hershberger, J.; Tanaka, R.; Wood, J. C.; Kaczmar, N.; Wu, D.; Hamilton, J. P.; DellaPenna, D.; Buell, C. R.; Gore, M. A.
10.1101/2021.09.24.461734 — genomics — Posted on 2021-09-25
679 Means, motive, and opportunity for biological invasions: genetic introgression in a fungal pathogen
Rogerio, F.; van Oosterhout, C.; Ciampi-Guillardi, M.; Correr, F. H.; Hosaka, G. K.; Cros-Arteil, S.; Margarido, G. R. A.; Massola, N. S.; Gladieux, P.
10.1101/2021.09.25.461217 — evolutionary biology — Posted on 2021-09-25
682 Direct reprogramming of the intestinal epithelium by parasitic helminths subverts type 2 immunity
Karo-Atar, D.; Ouladan, S.; Javkar, T.; Joumier, L.; Matheson, M. K.; Merritt, S.; Westfall, S.; Rochette, A.; Gentile, M. E.; Fontes, G.; Fonseca, G. J.; Parisien, M.; Diatchenko, L.; von Moltke, J.; Malleshaiah, M.; Gregorieff, A.; King, I. L.
10.1101/2021.09.25.461778 — immunology — Posted on 2021-09-25
684 Region-specific KCC2 rescue by rhIGF-1 and oxytocin in a mouse model of Rett syndrome
Gigliucci, V.; Teutsch, J.; Woodbury-Smith, M.; Luoni, M.; Busnelli, M.; Chini, B.; Banerjee, A.
10.1101/2021.09.25.460342 — neuroscience — Posted on 2021-09-25
686 'Wanting' versus 'Needing' related value: an fMRI meta-analysis
Bosulu, J.; Allaire, M.-A.; Tremblay-Grenier, L.; Luo, Y.; Eickhoff, S.; Hetu, S.
10.1101/2021.09.24.461758 — neuroscience — Posted on 2021-09-25
690 Single-cell RNA Sequencing Reveals Immunosuppressive Myeloid Cell Diversity and Restricted Cytotoxic Effector Cell Trafficking and Activation During Malignant Progression in Glioma
Rajendran, S.; Peterson, C.; Canella, A.; Hu, Y.; Gross, A.; Cam, M.; Serin Harmanci, A.; Distefano, R.; Nigita, G.; Wang, W.; Miller, K. E.; Elemento, O.; Roberts, R. D.; Holland, E. C.; Rao, G.; Mardis, E. R.; Rajappa, P.
10.1101/2021.09.24.461735 — cancer biology — Posted on 2021-09-25
691 Myofibril orientation as a metric for characterizing heart disease
Ma, W.; Gong, H.; Jani, V.; Landim-Vieira, M.; Papadaki, M.; Pinto, J.; Aslam, M. I.; Cammarato, A.; Irving, T.
10.1101/2021.09.24.461697 — biophysics — Posted on 2021-09-25
696 Leafy and Weedy Seadragon Genomes Connect Genic and Repetitive DNA Features to the Extravagant Biology of Syngnathid Fishes
Small, C. M.; Healey, H. M.; Currey, M. C.; Beck, E. A.; Catchen, J. M.; Lin, A. S.; Cresko, W. A.; Bassham, S.
10.1101/2021.09.24.461757 — genomics — Posted on 2021-09-25
699 Rapid in vivo development of resistance to daptomycin in vancomycin-resistant Enterococcus faecium due to genomic rearrangements
Mollerup, S.; Elmeskov, C.; Gumpert, H.; Pinholt, M.; Sejersen, T. S.; Pedersen, M. S.; Worning, P.; Frees, D.; Westh, H.
10.1101/2021.09.24.461763 — microbiology — Posted on 2021-09-25
700 Protein Vaccine Induces a Durable, More Broadly Neutralizing Antibody Response in Macaques than Natural Infection with SARS-CoV-2 P.1
To, A.; Wong, T. A. S.; Lieberman, M. M.; Thompson, K. S.; Pessaint, L.; Greenhouse, J.; Daham, N.; Cook, A.; Narvaez, B.; Flinchbaugh, Z.; Van Ry, A.; Yalley-Ogunro, J.; Andersen, H.; Lai, C.-Y.; Donini, O.; Lehrer, A. T.
10.1101/2021.09.24.461759 — immunology — Posted on 2021-09-25
701 LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein
Shilts, J.; Crozier, T. M.; Teixeira-Silva, A.; Gabaev, I.; Greenwood, E. J. D.; Watson, S. J.; Ortmann, B. M.; Gawden-Bone, C. M.; Pauzaite, T.; Hoffmann, M.; Nathan, J. A.; Pöhlmann, S.; Lehner, P. J.; Wright, G. J.
10.1101/2021.09.25.461776 — biochemistry — Posted on 2021-09-25
702 Caspase-4/11 exacerbates disease severity in SARS-CoV-2 infection by promoting inflammation and thrombosis
Eltobgy, M.; Zani, A.; Kenney, A.; Estfanous, S.; Kim, E.; Badr, A.; Carafice, C.; Daily, K.; Whitham, O.; Pietrzak, M.; Webb, A.; Kawahara, J.; Eddy, A.; Denz, P.; Lu, M.; KC, M.; Peeples, M.; Li, J.; Zhu, J.; Que, J.; Robinson, R.; Rosas Mejia, O.; Rayner, R.; Hall-Stoodley, L.; Seveau, S.; Gavrilin, M. A.; Tedeschi, A.; Partida-Sanchez, S.; Roberto, F.; Hemann, E.; Abdelrazik, E.; Forero, A.; Nimjee, S.; Boyaka, P.; Cormet-Boyaka, E.; Yount, J.; Amer, A.
10.1101/2021.09.24.461743 — immunology — Posted on 2021-09-25
703 LIGHTHOUSE illuminates therapeutics for a variety of diseases including COVID-19
Shimizu, H.; Kodama, M.; Matsumoto, M.; Orba, Y.; Sasaki, M.; Sato, A.; Sawa, H.; Nakayama, K. I.
10.1101/2021.09.25.461785 — systems biology — Posted on 2021-09-25
704 Control of subunit stoichiometry in single-chain MspA nanopores
Pavlenok, M.; Yu, L.; Herrmann, D.; Wanunu, M.; Niederweis, M.
10.1101/2021.09.25.461773 — biophysics — Posted on 2021-09-25
706 Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD
Ma, H.; Guo, Y.; Tang, H.; Tseng, C.-T.; Wang, L.; Zong, H.; Wang, Z.; He, Y.; Chang, Y.; Wang, S.; Huang, H.; Ke, Y.; Yuan, Y.; Wu, M.; Zhang, Y.; Drelich, A.; Kempaiah, K.; Peng, B.-H.; Wang, A.; Yang, K.; Yin, H.; Liu, J.; Yue, Y.; Xu, W.; Zhu, S.; Ji, T.; Zhang, X.; Wang, Z.; Li, G.; Liu, G.; Song, J.; Mu, L.; Xiang, Z.; Song, Z.; Chen, H.; Bian, Y.; Zhang, B.; Chen, H.; Zhang, J.; Liao, Y.; Zhang, L.; Yang, L.; Chen, Y.; Gilly, J.; Xiao, X.; Han, L.; Jiang, H.; Xie, Y.; Zhou, Q.; Zhu, J.
10.1101/2021.09.24.461616 — cell biology — Posted on 2021-09-25
707 DHODH is an independent prognostic marker and potent therapeutic target in neuroblastoma
Olsen, T. K.; Dyberg, C.; Embaie, B.; Alchahin, A.; Milosevic, J.; Otte, J.; Tummler, C.; Myrberg, I. H.; Westerhout, E. M.; Koster, J.; Versteeg, R.; Kogner, P.; Johnsen, J. I.; Sykes, D. B.; Baryawno, N.
10.1101/2021.09.25.461496 — cancer biology — Posted on 2021-09-25
709 Age of diabetes onset in the mutant proinsulin syndrome correlates with mutational impairment of protein foldability and stability
Dhayalan, B.; Chen, Y.-S.; Yang, Y.; Jarosinski, M.; Chatterjee, D.; Grabowski, R.; Poordian, S.; Phillips, N. F. B.; Arvan, P.; Ismail-Beigi, F.; Weiss, M. A.
10.1101/2021.09.24.461687 — biochemistry — Posted on 2021-09-25
715 Inactivation of the entire Arabidopsis group II GH3s confers tolerance to salinity and drought
Casanova-Saez, R.; Mateo-Bonmati, E.; Simura, J.; Pencik, A.; Novak, O.; Staswick, P.; Ljung, K.
10.1101/2021.09.24.461718 — plant biology — Posted on 2021-09-25
716 KEAP1 mutation in lung adenocarcinoma promotes immune evasion and immunotherapy resistance
Zavitsanou, A. M.; Hao, Y.; Wu, W. L.; Bartnicki, E.; Pillai, R.; Karakousi, T.; Herrera, A.; Karatza, A.; Rashidfarrokhi, A.; Solis, S.; Ciampricotti, M.; Yeaton, A. H.; Ivanova, E.; Wohlhieter, C. A.; Buus, T. B.; Poirier, J. T.; Rudin, C. M.; Wong, K.-K.; Moreira, A. L.; Khanna, K. M.; Tsirigos, A.; Papagiannakopoulos, T.; Koralov, S. B.
10.1101/2021.09.24.461709 — cancer biology — Posted on 2021-09-25
717 Insight into mammary gland development and tumor prevention in a newly developed metastatic mouse model of breast cancer
To, B.; Broeker, C.; Jhan, J.-R.; Rempel, R.; Rennhack, J. P.; Hollern, D.; Jackson, L.; Judah, D.; Swiatnicki, M.; Bylett, E.; Kubiak, R.; Honeysett, J.; Reaz, S.; Nevins, J. R.; Andrechek, E. R.
10.1101/2021.09.24.461727 — cancer biology — Posted on 2021-09-25
721 Fast and accurate annotation of acoustic signals with deep neural networks
Steinfath, E.; Palacios, A.; Rottschaefer, J.; Yuezak, D.; Clemens, J.
10.1101/2021.03.26.436927 — neuroscience — Posted on 2021-09-25
722 Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through cAMP/PKA pathway
Wang, S.; van Rhijn, J.-R.; Akkouh, I. A.; Kogo, N.; Maas, N.; Bleeck, A.; Ortiz, I. S.; Lewerissa, E.; Wu, K. M.; Schoenmaker, C.; Djurovic, S.; van Bokhoven, H.; Kleefstra, T.; Kasri, N. N.; Schubert, D.
10.1101/2021.05.25.445613 — neuroscience — Posted on 2021-09-25
723 Transoceanic voyages of drywood termites (Isoptera: Kalotermitidae) inferred from extant and extinct species
Bucek, A.; Wang, M.; Sobotnik, J.; Sillam-Dusses, D.; Mizumoto, N.; Stiblik, P.; Clitheroe, C.; Lu, T.; Gonzalez Plaza, J. J.; Mohagan, A.; Rafanomezantsoa, J. J.; Fisher, B.; Engel, M.; Roisin, Y.; Evans, T.; Scheffrahn, R.; Bourguignon, T.
10.1101/2021.09.24.461667 — evolutionary biology — Posted on 2021-09-25
726 Rostral Anterior Cingulate Activations inversely relate to Reward Payoff Maximation & predict Depressed Mood
Balasubramani, P. P.; Diaz-Delgado, J.; Grennan, G.; Zafar-Khan, M.; Alim, F.; Ramanathan, D.; Mishra, J.
10.1101/2021.06.11.447974 — neuroscience — Posted on 2021-09-25
730 Recombination of repeat elements generates somatic complexity in human genomes.
Pascarella, G.; Hashimoto, K.; Busch, A.; Luginbuehl, J.; Parr, C.; Hon, C.-C.; Yip, W. H.; Abe, K.; Kratz, A.; Bonetti, A.; Agostini, F.; Severin, J.; Murayama, S.; Suzuki, Y.; Gustincich, S.; Frith, M.; Carninci, P.
10.1101/2020.07.02.163816 — genomics — Posted on 2021-09-24
731 Evolution of host-microbe cell adherence by receptor domain shuffling
Baker, E. P.; Sayegh, R.; Kohler, K. M.; Borman, W.; Goodfellow, C. K.; Brush, E. R.; Barber, M. P.
10.1101/2021.08.24.457561 — evolutionary biology — Posted on 2021-09-24
735 Unique spatiotemporal fMRI dynamics in the awake mouse brain
Singh, N. A.; Gutierrez-Barragan, D.; Alvino, F.; Coletta, L.; Rocchi, F.; De Guzman, E. A.; Galbusera, A.; Panzeri, S.; Uboldi, M.; Gozzi, A.
10.1101/2021.08.24.457302 — neuroscience — Posted on 2021-09-24
738 Experience-Driven Rate Modulation is Reinstated During Hippocampal Replay
Tirole, M.; Huelin Gorriz, M.; Takigawa, M.; Kukovska, L.; Bendor, D.
10.1101/2021.07.15.452506 — neuroscience — Posted on 2021-09-25
739 Almost nontoxic tetrodotoxin analog, 5,6,11-trideoxytetrodotoxin, as an olfactory chemoattractant for the grass puffer
Noguchi, Y.; Suzuki, T.; Matsutani, K.; Sakakibara, R.; Nakahigashi, R.; Adachi, M.; Nishikawa, T.; Abe, H.
10.1101/2021.09.12.459881 — zoology — Posted on 2021-09-24
740 Ectopic FVIII expression and misfolding in hepatocytes as a potential cause of human hepatocellular carcinoma
Kapelanski-Lamoureux, A.; Chen, Z.; Gao, Z.-h.; Deng, R.; Lazaris, A.; Lebeaupin, C.; Giles, L.; Malhotra, J.; Yong, J.; Zou, C.; de Jong, Y. P.; Metrakos, P.; Herzog, R. W.; Kaufman, R. J.
10.1101/2021.01.19.427220 — cancer biology — Posted on 2021-09-24
741 The Landscape of Receptor-Mediated Precision Cancer Combination Therapy: A Single-Cell Perspective
Ahmadi, S.; Sukprasert, P.; Vegesna, R.; Sinha, S.; Schischlik, F.; Artzi, N.; Khuller, S.; Schaffer, A. A.; Ruppin, E.
10.1101/2020.01.28.923532 — bioinformatics — Posted on 2021-09-24
742 BATL: Bayesian annotations for targeted lipidomics
Chitpin, J. G.; Surendra, A.; Nguyen, T. T.; Taylor, G. P.; Xu, H.; Alecu, I.; Ortega, R.; Tomlinson, J. J.; Crawley, A. M.; McGuinty, M.; Schlossmacher, M. G.; Saunders-Pullman, R.; Cuperlovic-Culf, M.; Bennett, S. A. L.; Perkins, T. J.
10.1101/2021.03.18.435788 — bioinformatics — Posted on 2021-09-24
744 The coordination of hip, knee and ankle joint angles during gait in soccer players and controls
Yaserifar, M.; Mohammadi, Z. F.; Hosseininejad, S. E.; Esmaili, I.; Afrakoti, P.; Meijer, K.; Boonstra, T. W.
10.1101/2021.09.24.461658 — bioengineering — Posted on 2021-09-24
745 Massively parallel pooled screening reveals genomic determinants of nanoparticle-cell interactions
Boehnke, N.; Straehla, J. P.; Safford, H. C.; Kocak, M.; Rees, M. G.; Ronan, M.; Rosenberg, D.; Adelmann, C. H.; Chivukula, R. R.; Cheah, J. H.; Li, H.; Roth, J. A.; Koehler, A. N.; Hammond, P. T.
10.1101/2021.04.05.438521 — bioengineering — Posted on 2021-09-24
748 TatA and TatB generate a hydrophobic mismatch that is important for function and assembly of the Tat translocon in Escherichia coli
Mehner-Breitfeld, D.; Ringel, M. T.; Tichy, D. A.; Endter, L. J.; Stroh, K. S.; Luensdorf, H.; Risselada, H. J.; Brueser, T.
10.1101/2021.05.26.445790 — biochemistry — Posted on 2021-09-24
749 Sub-sampling of cues in associative learning
Perez, O. D.; Vogel, E. H.; Narasiwodeyar, S.; Soto, F. A.
10.1101/713420 — animal behavior and cognition — Posted on 2021-09-24
754 Mammals adjust diel activity across gradients of urbanization
Gallo, T.; Fidino, M.; Gerber, B.; Ahlers, A. A.; Angstmann, J. L.; Amaya, M.; Concilio, A. L.; Drake, D.; Gay, D.; Lehrer, E. W.; Murray, M. H.; Ryan, T. J.; St. Clair, C. C.; Salsbury, C. M.; Sander, H. A.; Stankowich, T.; Williamson, J.; Belaire, J. A.; Simon, K.; Magle, S.
10.1101/2021.09.24.461702 — ecology — Posted on 2021-09-24
755 The H4K20 demethylase DPY-21 regulates thedynamics of condensin DC binding
Breimann, L.; Morao, A. K.; Kim, J.; Jimenez, D.; Maryn, N.; Bikkasani, K.; Carrozza, M. J.; Albritton, S. E.; Kramer, M.; Street, L. A.; Cerimi, K.; Schumann, V.-F.; Bahry, E.; Preibisch, S.; Woehler, A.; Ercan, S.
10.1101/2021.04.11.438056 — cell biology — Posted on 2021-09-24
758 Histone deacetylase inhibition reduces deleterious cytokine release induced by ingenol stimulation
Larragoite, E. T.; Nell, R. A.; Martins, L. J.; Barrows, L. R.; Planelles, V.; Spivak, A. M.
10.1101/193946 — microbiology — Posted on 2021-09-24
759 Complete sequences of epidermin and nukacin encoding plasmids from oral-derived Staphylococcus epidermidis and their antibacterial activity
Kawada-Matsuo, M.; Nakazono, K.; Le, M. N.-T.; Kimheang, N.; Hisatsune, J.; Oogai, Y.; Nakata, M.; Nakamura, N.; Sugai, M.; Komatsuzawa, H.
10.1101/2021.09.24.461659 — microbiology — Posted on 2021-09-24
761 Distinct ground state and activated state modes of spiking in forebrain neurons
Levenstein, D.; Girardeau, G.; Gornet, J.; Grosmark, A.; Huszar, R.; Peyrache, A.; Senzai, Y.; Watson, B.; Rinzel, J.; Buzsaki, G.
10.1101/2021.09.20.461152 — neuroscience — Posted on 2021-09-24
764 Physiological and molecular responses to combinatorial iron and phosphate deficiencies in hexaploid wheat seedlings
Kaur, G.; Shukla, V.; Meena, V.; Kumar, A.; Tyagi, D.; Singh, J.; Kandoth, P. K.; Mantri, S.; Rouached, H.; Pandey, A. K.
10.1101/2020.05.26.117101 — plant biology — Posted on 2021-09-24
765 Temporal change in chromatin accessibility predicts regulators of nodulation in Medicago truncatula
Knaack, S. A.; Conde, D.; Balmant, K. M.; Irving, T. B.; Gontijo Silva Maia, L.; Triozzi, P. M.; Dervinis, C.; Pereira, W. J.; Maeda, J.; Chakraborty, S.; Schmidt, H. W.; Ane, J.-M.; Kirst, M.; Roy, S.
10.1101/2021.08.07.455463 — plant biology — Posted on 2021-09-24
766 Hemodynamic evaluation of chemical mediators of sepsis during systemic inflammatory response in an experimental animal model
VIEIRA, G. D. S.; Antunes, F.; Machado, J. A.; Morales, I. C.; de Jesus, P. O. B.; do Amaral, A. d. F.; de Abreu Oliveira, A. L.
10.1101/2021.09.24.461714 — pathology — Posted on 2021-09-24
767 Local accessory gene sharing drives lineage-specific acquisition of antimicrobial resistance in Egyptian Campylobacter spp.
Mouftah, S. F.; Pascoe, B.; Calland, J. K.; Mourkas, E.; Tonkin, N.; Lefevre, C.; Deuker, D.; Smith, S.; Wickenden, H.; Hitchings, M. D.; Sheppard, S. K.; Elhadidy, M.
10.1101/2021.09.24.461243 — microbiology — Posted on 2021-09-24
768 Phostensin Enables Lymphocyte Integrin Activation and Population of Peripheral Lymphoid Organs
Ginsberg, M.; Sun, H.; Gingras, A.; Lee, H.; Lagarrigue, F.; Fox, J. W.; Sherman, N. E.
10.1101/2021.09.24.461584 — immunology — Posted on 2021-09-24
772 Overcoming microenvironment-mediated chemoprotection through stromal Galectin-3 inhibition in acute lymphoblastic leukemia
Heisterkamp, N.; Tarighat, S. S.; Fei, F.; Joo, E. j.; Abdel-Azim, H.; Bum-Erdene, K.; Grice, D.; Blanchard, H.; von Itzstein, M.; Geng, H.; Yang, L.
10.1101/2021.09.24.461149 — cancer biology — Posted on 2021-09-24
773 Fabrication and delivery of mechano-activedmicrocapsules containing osteogenic factors in alarge animal model of osteochondral injury
Zlotnick, H. M.; Locke, R. C.; Hemdev, S.; Stoeckl, B. D.; Gupta, S.; Peredo, A. P.; Steinberg, D. R.; Carey, J. L.; Lee, D.; Dodge, G. R.; Mauck, R. L.
10.1101/2021.09.24.461696 — bioengineering — Posted on 2021-09-24
775 Systemic impact of the expression of the mitochondrial alternative oxidase on Drosophila development
Camargo, A. F.; Saari, S.; Garcia, G. S.; Chioda, M. M.; Othonicar, M. F.; Martins, A. A.; Hayashi, G.; ten Hoeve, J.; Jacobs, H. T.; Pinheiro, D. G.; Dufour, E.; Oliveira, M. T.
10.1101/2021.09.24.461559 — biochemistry — Posted on 2021-09-24
776 Reconstitution and use of highly active human CDK1:Cyclin-B:CKS1 complexes
Huis in t Veld, P. J.; Wohlgemuth, S.; Koerner, C.; Mueller, F.; Janning, P.; Musacchio, A.
10.1101/2021.09.24.461690 — biochemistry — Posted on 2021-09-24
778 Transoceanic voyages of drywood termites (Isoptera: Kalotermitidae) inferred from extant and extinct species
Bucek, A.; Wang, M.; Sobotnik, J.; Sillam-Dusses, D.; Mizumoto, N.; Stiblik, P.; Clitheroe, C.; Lu, T.; Gonzalez Plaza, J. J.; Mohagan, A.; Rafanomezantsoa, J. J.; Fisher, B.; Engel, M.; Roisin, Y.; Evans, T.; Scheffrahn, R.; Bourguignon, T.
10.1101/2021.09.24.461667 — evolutionary biology — Posted on 2021-09-24
783 Apixaban, an orally available anticoagulant, inhibits SARS-CoV-2 replication by targeting its major protease in a non-competitive way
Chaves, O. A.; Sacramento, C. Q.; Fintelman-Rodrigues, N.; Temerozo, J. R.; Pereira-Dutra, F.; Mizurini, D. M.; Monteiro, R. Q.; Vazquez, L.; Bozza, P. T.; Castro-Faria-Neto, H. C.; Souza, T. M. L.
10.1101/2021.09.23.461605 — microbiology — Posted on 2021-09-24
784 A Drosophila Su(H) Model of Adams-Oliver Syndrome Reveals Notch Cofactor Titration as a Mechanism Underlying Developmental Defects
Gagliani, E. K.; Gutzwiller, L. M.; Kuang, Y.; Odaka, Y.; Hoffmeister, P.; Hauff, S.; Turkiewicz, A.; Harding-Theobald, E.; Dolph, P. J.; Borggrefe, T.; Oswald, F.; Gebelein, B.; Kovall, R. A.
10.1101/2021.09.24.461537 — genetics — Posted on 2021-09-24
785 The retromer complex regulates C. elegans development and mammalian ciliogenesis
Xie, S.; Smith, E.; Dierlam, C.; Mathew, D.; Davis, A.; Williams, A.; Naslavsky, N.; Iyer, J.; Caplan, S.
10.1101/2021.09.24.461716 — cell biology — Posted on 2021-09-24
800 Functional Communication between IP3R and STIM2 at sub-threshold stimuli is a critical checkpoint for initiation of SOCE
Ahmad, M.; Ong, H. L.; Saadi, H.; Son, G.-Y.; Shokatian, Z.; Terry, L. E.; Trebak, M.; Yule, D. I.; Ambudkar, I.
10.1101/2021.09.24.461545 — physiology — Posted on 2021-09-24
804 Purinergic receptor P2RY14 cAMP signaling regulates EGFR-driven Schwann cell precursor self-renewal and nerve tumor initiation in neurofibromatosis.
Patritti-Cram, J.; Wu, J.; Kuninaka, S.; Coover, R. A.; Hennigan, R. F.; Rizvi, T. A.; Chaney, K. E.; Ravindran, R.; Cancelas, J. A.; Spinner, R. J.; Ratner, N.
10.1101/2021.09.24.461701 — neuroscience — Posted on 2021-09-24
805 Live Monitoring of Inflammation Reveals Tissue and Sex-specific Responses to Western Diet and Butyrate treatment
Bonomo, r.; Talley, s.; Hatahet, J.; Gavini, C.; cook, t.; Chun, B.; Kekenes-Huskey, P.; aubert, g.; Campbell, E. M.; Aubert, V.
10.1101/2021.09.22.461384 — neuroscience — Posted on 2021-09-24
807 A network model of glymphatic flow under different experimentally-motivated parametric scenarios
Tithof, J.; Boster, K. A. S.; Bork, P. A. R.; Nedergaard, M.; Thomas, J. H.; Kelley, D. H.
10.1101/2021.09.23.461519 — neuroscience — Posted on 2021-09-24
810 Domain General Processes for Interactive Touch
Buck, T.; DiCocco, C.; Cuzzocreo, J. L.; Noah, J. A.; Zhang, X.; Hirsch, J.
10.1101/2021.09.23.461532 — neuroscience — Posted on 2021-09-24
811 Neonatal multi-modal cortical profiles predict 18-month developmental outcomes
Fenchel, D.; Dimitrova, R.; Robinson, E. C.; Batalle, D.; Chew, A.; Falconer, S.; Kyriakopoulou, V.; Nosarti, C.; Hutter, J.; Christiaens, D.; Pietsch, M.; Brandon, J.; Hughes, E. J.; Allsop, J.; O'Keeffe, C.; Price, A. N.; Cordero-Grande, L.; Schuh, A.; Makropoulos, A.; Passerat-Palmbach, J.; Bozek, J.; Rueckert, D.; Hajnal, J. V.; McAlonan, G.; Edwards, A. D.; O'Muircheartaigh, J.
10.1101/2021.09.23.461464 — neuroscience — Posted on 2021-09-24
812 LXR agonist Prevents Peripheral Neuropathy and modifies PNS immune cells in Aged Mice
Gavini, C.; Elshareif, N.; Germanwala, A.; Aubert, G.; Calcutt, N.; Aubert, V.
10.1101/2021.09.22.461263 — neuroscience — Posted on 2021-09-24
813 AI-driven high-throughput automation of behavioral analysis and dual-channel wireless optogenetics for multiplexing brain dynamics
Kim, W. S.; Liu, J.; Li, Q.; Hong, S.; Qi, K.; Cherukur, R.; Yoon, B.-J.; Moscarello, J.; Choe, Y.; Maren, S.; Park, S. i.
10.1101/2021.09.23.461279 — neuroscience — Posted on 2021-09-24
815 A rise-to-threshold signal for a relative value deliberation
Vijayan, V.; Wang, F.; Wang, K.; Chakravorty, A.; Adachi, A.; Akhlaghpour, H.; Dickson, B. J.; Maimon, G.
10.1101/2021.09.23.461548 — neuroscience — Posted on 2021-09-24
818 Vertex-wise characterization of Non-Human Primate cortical development with prenatal insights.
Ramirez, J. S. B.; Hermosillo, R.; Thomas, E.; Zhu, J. Y.; Sturgeon, D.; Schifsky, E.; Galassi, A.; Thompson, J. R.; Bagley, J. L.; Milham, M. P.; Miranda-Dominguez, O.; Papadakis, S.; Bah, M.; Mitchell, A.; Xu, T.; Graham, A. M.; Feczko, E.; Sullivan, E. L.; Fair, D. A.
10.1101/2021.09.23.461551 — neuroscience — Posted on 2021-09-24
819 Traumatic Brain Injury Exacerbates Alzheimer's Disease Pathology in the Retinas of TgF344-AD Rats
Secora, C.; Vielle, A.; Wang, A. C.-J.; Lenhart, P.; Salcedo, E.; Johnson, N. R.; Ahmed, M. M.; Chial, H. J.; Boyd, T. D.; Potter, H.; Vergara, M. N.
10.1101/2021.09.23.461334 — neuroscience — Posted on 2021-09-24
821 Concurrent tau pathologies in frontotemporal lobar degeneration with TDP-43 pathology
Koga, S.; Zhou, X.; Murakami, A.; Fernandez De Castro, C.; Baker, M. C.; Rademakers, R.; Dickson, D. W.
10.1101/2021.09.23.461523 — pathology — Posted on 2021-09-24
829 Batch effects removal for microbiome data via conditional quantile regression (ConQuR)
Ling, W.; Zhao, N.; Lulla, A.; Plantinga, A. M.; Fu, W.; Zhang, A.; Liu, H.; Li, Z.; Chen, J.; Randolph, T.; Koay, W. L. A.; White, J. R.; Launer, L. J.; Fodor, A. A.; Meyer, K. A.; Wu, M. C.
10.1101/2021.09.23.461592 — bioinformatics — Posted on 2021-09-24
831 Solvent Precipitation SP3 (SP4) enhances recovery for proteomics sample preparation without magnetic beads
Johnston, H. E.; Yadav, K.; Kirkpatrick, J. M.; Biggs, G. S.; Oxley, D.; Kramer, H. B.; Samant, R. S.
10.1101/2021.09.24.461247 — biochemistry — Posted on 2021-09-24
836 High-resolution mapping of DNA alkylation damage and base excision repair at yeast transcription factor binding sites
Mao, P.; Duan, M.; Sivapragasam, S.; Antony, J. S.; Ulibarri, J.; Hinz, J. M.; Poon, G. M. K.; Wyrick, J. J.
10.1101/2021.09.24.461700 — genomics — Posted on 2021-09-24
837 RNA nucleotide repeats induce mitochondrial dysfunction and the ribosome associated quality control
Teixeira, J.; Harju, A.-M.; Othman, A.; Eriksson, O.; Brandao, A. S.; Battersby, B.; Garcia, S. M. D. A.
10.1101/2021.09.24.461665 — genetics — Posted on 2021-09-24
838 Meta-analysis of immune induced gene expression changes in diverse Drosophila melanogaster innate immune responses
Waring, A. L.; Hill, J.; Allen, B. M.; Bretz, N. M.; Le, N.; Kr, P.; Fuss, D.; Mortimer, N. T.
10.1101/2021.09.23.461556 — genetics — Posted on 2021-09-24
843 Coat color mismatch improves survival of a keystone boreal herbivore: energetic advantages exceed lost camouflage
Kennah, J. L.; Peers, M. J. L.; Vander Wal, E.; Majchrzak, Y. N.; Menzies, A. K.; Studd, E. K.; Boonstra, R.; Humphries, M. M.; Jung, T. S.; Kenney, A. J.; Krebs, C. J.; Boutin, S.
10.1101/2021.09.24.461654 — ecology — Posted on 2021-09-24
847 A method to enrich and purify centromeric DNA from human cells
Gamba, R.; Mazzucco, G.; Wilhelm, T.; Chardon, F.; Velikovsky, L.; Picotto, J.; Doksani, Y.; Fachinetti, D.
10.1101/2021.09.24.461328 — molecular biology — Posted on 2021-09-24
848 Towards a combined therapy for spinal muscular atrophy based on opposing effects of an antisense oligonucleotide on chromatin and splicing
Marasco, L. E.; Dujardin, G.; Sousa-Luis, R.; Hsiu Liu, Y.; Stigliano, J.; Nomakuchi, T.; Proudfoot, N. R.; Krainer, A.; Kornblihtt, A. R.
10.1101/2021.09.24.461646 — molecular biology — Posted on 2021-09-24
851 Characterization of Cervical-Cranial Muscle Network in Correlation with Vocal Features
O'Keeffe, R.; Shirazi, S. Y.; Mehrdad, S.; Crosby, T.; Johnson, A. M.; Atashzar, S. F.
10.1101/2021.09.23.461177 — neuroscience — Posted on 2021-09-24
853 The impact of phosphorylated Pten at threonine 366 on cortical connectivity and behaviour
Ledderose, J.; Benitez, J. A.; Roberts, A. J.; Reed, R.; Bintig, W.; Sachdev, R.; Furnari, F.; Eickholt, B.
10.1101/2021.09.22.461341 — neuroscience — Posted on 2021-09-24
854 Pathological and metabolic underpinnings of energetic inefficiency in temporal lobe epilepsy
He, X.; Caciagli, L.; Parkes, L. M.; Stiso, J.; Karrer, T. M.; Kim, J. Z.; Lu, Z.; Menara, T.; Pasqualetti, F.; Sperling, M. R.; Tracy, J. I.; Bassett, D. S.
10.1101/2021.09.23.461495 — neuroscience — Posted on 2021-09-24
856 Compositional phylogenomic modelling resolves the 'Zoraptera problem': Zoraptera are sister to all other polyneopteran insects
Tihelka, E.; Engel, M. S.; Lozano-Fernandez, J.; Giacomelli, M.; Yin, Z.; Rota-Stabelli, O.; Huang, D.; Pisani, D.; Donoghue, P.; Cai, C.
10.1101/2021.09.23.461539 — zoology — Posted on 2021-09-24
857 Integrative analysis allows a global and precise identification of functional miRNA target genes in mESCs
Schaefer, M.; Nabih, A.; Spies, D.; Bodak, M.; Wischnewski, H.; Stalder, P.; Ngondo, R. P.; Liechti, L. A.; Sajic, T.; Aebersold, R.; Gatfield, D.; Ciaudo, C.
10.1101/2021.09.24.461622 — systems biology — Posted on 2021-09-24
859 DcPAR1 Is Required For Development And Carotenoid Synthesis In The Dark-Grown Carrot Taproot
Arias, D.; Ortega, A.; Gonzalez-Calquin, C.; Quiroz, L. F.; Moreno-Romero, J.; Martinez-Garcia, J. F.; Stange, C. R.
10.1101/2021.09.22.461395 — plant biology — Posted on 2021-09-24
860 Balancing growth amidst salinity stress-lifestyle perspectives from the extremophyte model Schrenkiella parvula
Tran, K.-N.; Pantha, P.; Wang, G.; Kumar, N.; Wijesinghege, C.; Oh, D.-H.; Duppen, N.; Li, H.; Hong, H.; Johnson, J. C.; Kelt, R.; Matherne, M. G.; Clement, A.; Tran, D.; Crain, C.; Adhikari, P.; Zhang, Y.; Foroozani, M.; Sessa, G.; Larkin, J. C.; Smith, A. P.; Longstreth, D.; Finnegan, P.; Testerink, C.; Barak, S.; Dassanayake, M.
10.1101/2021.08.27.457575 — plant biology — Posted on 2021-09-24
868 Energy efficient convolutional neural networks for arrhythmia detection
Katsaouni, N.; Aul, F.; Krischker, L.; Schmalhofer, S.; Hedrich, L.; Schulz, M. H.
10.1101/2021.09.23.461522 — bioinformatics — Posted on 2021-09-24
870 An innovative optical context to make honeybees crash repeatedly
Serres, J. R.; Morice, A. H.; Blary, C.; Miot, R.; Montagne, G.; Ruffier, F.
10.1101/2021.09.23.461476 — animal behavior and cognition — Posted on 2021-09-24
873 A Comparative Genome-wide Transcriptome Analysis of Glucocorticoid Responder and Non-Responder Primary Human Trabecular Meshwork Cells
Kandasamy, K.; Haribalaganesh, R.; Krishnadas, R.; Muthukkaruppan, V.; Willoughby, C. E.; Bharanidharan, D.; Srinivasan, S.
10.1101/2021.09.21.461315 — genomics — Posted on 2021-09-24
876 Genetic effect modification of cis-acting C-reactive protein variants in cardiometabolic disease status
Zheng, J.; Tang, H.; Lyon, M. S.; Davies, N. M.; Walker, V. M.; Floyd, J.; Austin, T. R.; Shojaie, A.; Psaty, B. M.; Gaunt, T. R.; Smith, G. D.
10.1101/2021.09.23.461369 — genetics — Posted on 2021-09-24
877 Dominant negative effects of SCN5A missense variants
O'Neill, M. J.; Muhammad, A.; Li, B.; Wada, Y.; Hall, L.; Solus, J.; Short, L.; Roden, D. M.; Glazer, A. M.
10.1101/2021.09.22.461398 — genetics — Posted on 2021-09-24
878 Tyr is Responsible for the Cctq1a QTL and Links Developmental Environment to Central Corneal Thickness Determination
Meyer, K. J.; Larson, D. R.; Whitmore, S. S.; van der Heide, C. J.; Hedberg-Buenz, A.; Dutca, L. M.; Koli, S.; Pomernackas, N.; Mercer, H. E.; Mansaray, M. N.; Paradee, W. J.; Wang, K.; Nair, K. S.; Scheetz, T. E.; Anderson, M. G.
10.1101/2021.09.22.461410 — genetics — Posted on 2021-09-24
880 Genetic studies of human-chimpanzee divergence using stem cell fusions
Song, J. H.; Grant, R. L.; Behrens, V. C.; Kucka, M.; Roberts Kingman, G. A.; Soltys, V.; Chan, Y. F.; Kingsley, D. M.
10.1101/2021.09.24.461617 — evolutionary biology — Posted on 2021-09-24
883 A global meta-analysis reveals more variable life histories in urban birds compared to their non-urban neighbours
Capilla-Lasheras, P.; Thompson, M. J.; Sanchez-Tojar, A.; Haddou, Y.; Branston, C. J.; Reale, D.; Charmantier, A.; Dominoni, D. M.
10.1101/2021.09.24.461498 — evolutionary biology — Posted on 2021-09-24
885 Early anteroposterior regionalisation of human neural crest is shaped by a pro-mesodermal factor
Gogolou, A.; Souilhol, C.; Granata, I.; Wymeersch, F. J.; Manipur, I.; Wind, M.; Frith, T. J.; Guarini, M.; Bertero, A.; Bock, C.; Halbritter, F.; Takasato, M.; Guarracino, M. R.; Tsakiridis, A.
10.1101/2021.09.24.461516 — developmental biology — Posted on 2021-09-24
887 How Our Cells Become Our Selves: The Cellular Phylodynamic Biology of Growth and Development
Chodrow, P.; Su, J.; Lee, D.; Ahmed, T.; He, N.; De Man, R.; Tiwari, A.; Mannherz, W.; Citi, L.; DiCorpo, D.; Michaelson, J. S.
10.1101/2021.09.22.461268 — developmental biology — Posted on 2021-09-24
889 The mosquito microbiome includes habitat-specific but rare symbionts
Schrieke, H.; Maignien, L.; Constancias, F.; Trigodet, F.; Chakloute, S.; Rakotoarivony, I.; Marie, A.; L'Ambert, G.; Makoundou, P.; Pages, N.; Eren, A. M.; Weill, M.; Sicard, M.; Reveillaud, J.
10.1101/2021.09.24.461628 — microbiology — Posted on 2021-09-24
890 Immune checkpoint expression on HIV-specific CD4+ T cells and response to their blockade are dependent on lineage and function
Brunet-Ratnasingham, E.; Morou, A.; Dube, M.; Niessl, J.; Baxter, A. E.; Tastet, O.; Brassard, N.; Ortega-Delgado, G.; Charlebois, R.; Freeman, G. J.; Tremblay, C.; Routy, J.-P.; Kaufmann, D. E.
10.1101/2021.09.23.461484 — immunology — Posted on 2021-09-24
891 Active Translation Control of CD4 T Cell Activation by Regulatory T Cells
So, L.; Obata-Ninomiya, K.; Hu, A.; Muir, V.; Takamori, A.; Savan, R.; Ziegler, S.
10.1101/2021.09.23.461566 — immunology — Posted on 2021-09-24
893 Engineering CAR-NK cells to secrete IL15 sustains their anti-AML functionality, but is associated with systemic toxicities
Christodoulou, I.; Ho, W. J.; Marple, A.; Ravich, J. W.; Tam, A.; Rahnama, R.; Fearnow, A.; Rietberg, C.; Yanik, S.; Solomou, E. E.; Varadhan, R.; Koldobskiy, M. A.; Bonifant, C. L.
10.1101/2021.09.23.461509 — immunology — Posted on 2021-09-24
895 Targeting of Cdc42 GTPase in regulatory T cells unleashes anti-tumor T cell immunity
Kalim, K. W.; Yang, J.-Q.; Wunderlich, M.; Modur, V.; Nguyen, P.; Li, Y.; Wen, T.; Kuenzi, A.; Verma, R.; Lu, Q. R.; Jegga, A. G.; Zheng, Y.; Guo, F.
10.1101/2021.09.23.461402 — immunology — Posted on 2021-09-24
896 Altered synaptic connectivity in an in vitro human model of STXBP1 encephalopathy
McLeod, F.; Dimtsi, A.; Lewis-Smith, D.; Thomas, R.; Clowry, G. J.; Trevelyan, A. J.
10.1101/2021.09.22.461333 — neuroscience — Posted on 2021-09-24
897 The impact of genetic risk for Alzheimers disease on the structural brain networks of young adults
Mirza-Davies, A.; Foley, S.; Caseras, X.; Baker, E.; Holmans, P.; Escott-Price, V.; Jones, D. K.; Harrison, J. R.; Messaritaki, E.
10.1101/2021.09.22.461338 — neuroscience — Posted on 2021-09-24
898 A Comparison of Methods to Harmonize Cortical Thickness Measurements Across Scanners and Sites
Sun, D.; Rakesh, G.; Clarke-Rubright, E. K.; Haswell, C. C.; Logue, M.; O'Leary, B. M.; Cotton, A. S.; Xie, H.; Dennis, E. L.; Jahanshad, N.; Salminen, L. E.; Thomopolous, S. I.; Rashid, F.; Ching, C. R. K.; Koch, S. B. J.; Frijling, J. L.; Nawijn, L.; van Zuiden, M.; Zhu, X.; Suarez-Jimenez, B.; Sierk, A.; Walter, H.; Manthey, A.; Stevens, J. S.; Fani, N.; van Rooij, S. J. H.; Stein, M.; Bomyea, J.; Koerte, I. K.; Choi, K.; van der Werff, S. J. A.; Vermeiren, R. R. J. M.; Herzog, J.; Lebois, L. A. M.; Baker, J. T.; Ressler, K. J.; Olson, E. A.; Straube, T.; Korgaonkar, M. S.; Andrew, E.; Zhu,
10.1101/2021.09.22.461242 — neuroscience — Posted on 2021-09-24
900 Assessing the relationships between neurological and psychiatric diseases with astrocyte subtypes and psychotropic medications
Zhang, X.; Wolfinger, A. M.; Shukla, R. M.; Lundh, A. E.; Wu, X.; Abel, M.; McCullumsmith, R. E.; O'Donovan, S. M.
10.1101/2021.09.22.461367 — neuroscience — Posted on 2021-09-24
902 Novel microRNA-455-3p mouse models to study Alzheimers disease pathogenesis
kumar, S.; Mortan, H.; Sawant, N.; Orlov, E.; Bunquin, L.; Pradeepkiran, J. A.; Reddy, P. H. H.
10.1101/2021.09.23.461513 — neuroscience — Posted on 2021-09-24
904 Integrated phylogenomics and fossil data illuminate the evolution of beetles
Cai, C.; Tihelka, E.; Giacomelli, M.; Lawrence, J. F.; Slipinski, A.; Kundrata, R.; Yamamoto, S.; Thayer, M. K.; Newton, A. F.; Leschen, R. A. B.; Gimmel, M. L.; Lu, L.; Engel, M. S.; Huang, D.; Pisani, D.; Donoghue, P. C. J.
10.1101/2021.09.22.461358 — zoology — Posted on 2021-09-24
908 The ectomycorrhizal basidiomycete Laccaria bicolor releases a GH28 polygalacturonase that plays a key role in symbiosis establishment
Zhang, F.; Labourel, A.; Haon, M.; Kemppainen, M.; Machado, E. D. S.; Brouilly, N.; Veneault-Fourrey, C.; Kohler, A.; Rosso, M.-N.; Pardo, A.; Henrissat, B.; Berrin, J.-G.; Martin, F.
10.1101/2021.09.24.461608 — plant biology — Posted on 2021-09-24
909 Glutathione contributes to plant defense against parasitic cyst nematodes
Hasan, M. S.; Chopra, D.; Damm, A.; Koprivova, A.; Kopriva, S.; Meyer, A.; Mueller-Schuessele, S. J.; Grundler, F.; Siddique, S.
10.1101/2021.09.23.461554 — plant biology — Posted on 2021-09-24
911 Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids
Martino, M. R.; Gutierrez-Aguilar, M.; Yiew, N. K. H.; Lutkewitte, A. J.; Singer, J. M.; McCommis, K. S.; Smith, G. I.; Cho, K.; Fletcher, J. A.; Klein, S.; Patti, G. J.; Burgess, S. C.; Finck, B. N.
10.1101/2021.09.22.461414 — physiology — Posted on 2021-09-24
912 Inhibition of Bruton's tyrosine kinase activity attenuates trauma-induced multiple organ dysfunction in rats
Patel, N. M.; Oliveira, F. R.; Pillmann Ramos, H.; Aimaretti, E.; Ferreira Alves, G.; Coldewey, S. M.; Collino, M.; Sordi, R.; Thiemermann, C.
10.1101/2021.09.23.460775 — pharmacology and toxicology — Posted on 2021-09-24
913 Hyperconcentrated Mucus Unifies Submucosal Gland and Superficial Airway Dysfunction in Cystic Fibrosis
Kato, T.; Radicioni, G.; Papanikolas, M. J.; Stoychev, G. V.; Markovetz, M. R.; Aoki, K.; Porterfield, M.; Okuda, K.; Cardenas, S. M. B.; Gilmore, R. C.; Morrison, C. B.; Ehre, C.; Burns, K. A.; White, K. K.; Goodell, H. P.; Thacker, H.; Loznev, H. T.; Forsberg, L. J.; Nagase, T.; Rubinstein, M.; Randell, S. H.; Tiemeyer, M.; Hill, D. B.; Kesimer, M.; O'Neal, W. K.; Ballard, S. T.; Freeman, R.; Button, B.; Boucher, R. C.
10.1101/2021.09.22.461306 — pathology — Posted on 2021-09-24
914 Structures of plasmepsin X from P. falciparum reveal a novel inactivation mechanism of the zymogen and molecular basis for binding of inhibitors in mature enzyme
kesari, p.; Deshmukh, A.; Pahelkar, N.; Suryawanshi, A. B.; Rathore, I.; Mishra, V.; Dupuis, J. H.; Xiao, H.; Gustchina, A.; Abendroth, J.; Labaied, M.; Yada, R. Y.; Wlodawer, A.; Edwards, T. E.; Lorimer, D. D.; Bhaumik, P.
10.1101/2021.09.24.460453 — biophysics — Posted on 2021-09-24
915 PharmacoDB 2.0 : Improving scalability and transparency of in vitro pharmacogenomics analysis
Feizi, N.; Kadambat Nair, S.; Smirnov, P.; Beri, G.; Eeles, C.; Nasr Esfahani, P.; Nakano, M.; Tkachuk, D.; Mammoliti, A.; Gorobets, E.; Singh Mer, A.; Lin, E.; Yu, Y.; Martin, S.; Hafner, M.; Haibe-Kains, B.
10.1101/2021.09.21.461211 — bioinformatics — Posted on 2021-09-24
918 Optimised multiplex amplicon sequencing for mutation identification using the MinION nanopore sequencer
Whitford, W.; Hawkins, V.; Moodley, K.; Grant, M. J.; Lehnert, K.; Snell, R. G.; Jacobsen, J. C.
10.1101/2021.09.21.461312 — bioinformatics — Posted on 2021-09-24
919 pChem: a modification-centric assessment tool for the performance of chemoproteomic probes
He, J.-X.; Fei, Z.-C.; Fu, L.; Tian, C.-P.; He, F.-C.; He, S.-M.; Chi, H.; Yang, J.
10.1101/2021.09.22.461295 — bioinformatics — Posted on 2021-09-24
928 Engineered neuron-targeting, placental mesenchymal stromal cell-derived extracellular vesicles for in utero treatment of myelomeningocele
Zhang, X.; Chen, H.; Gao, K.; He, S.; Ma, Z.; Liu, R.; Hao, D.; Wang, Y.; Kumar, P.; Ramasubramanian, L.; Pivetti, C. D.; Li, Y.; Guo, F.; Wang, F.; Carney, R.; Farmer, D. L.; Wang, A.
10.1101/2021.09.22.461362 — bioengineering — Posted on 2021-09-24
930 PcGCE is a potent elicitor of defense responses in aspen
Donev, E. N.; Derba-Maceluch, M.; Liu, X.; Bwanika, H. C.; Dobrowolska, I.; Thapa, M.; Lesniewska, J.; Simura, J.; Tsai, A. Y.- L.; Boström, D.; Kleczkowski, L. A.; Eriksson, M. E.; Ljung, K.; Master, E. R.; Mellerowicz, E. J.
10.1101/2021.09.23.460629 — bioengineering — Posted on 2021-09-24
931 Anisotropic Rod-Shaped Particles Influence Injectable Granular Hydrogel Properties and Cell Invasion
Qazi, T. H.; Wu, J.; Muir, V.; Weintraub, S.; Gullbrand, S.; Lee, D.; Issadore, D.; Burdick, J.
10.1101/2021.09.23.461542 — bioengineering — Posted on 2021-09-24
932 Microbial Biotextiles for a Circular Materials Economy
Schiros, T. N.; Antrobus, R.; Farias, D.; Chiu, Y.-T.; Joseph, C. T.; Esdaille, S.; Sanchiricco, G. K.; Miquelon, G.; An, D.; Russell, S. T.; Chitu, A.; Goetz, S.; Chasse, A. M. V.; Nuckolls, C.; Kumar, S. K.; Lu, H. H.
10.1101/2021.09.22.461422 — bioengineering — Posted on 2021-09-24
936 A population based expression atlas provides insights into disease resistance and other physiological traits in cassava (Manihot esculenta Crantz)
Ogbonna, A. C.; Ramu, P.; Esuma, W.; Nandudu, L.; Morales, N.; Powell, A.; Kawuki, R.; Bauchet, G. J.; Janninck, J.-L.; Mueller, L. A.
10.1101/2021.09.23.461500 — genomics — Posted on 2021-09-24
937 The genome of an apodid holothuroid (Chiridota heheva) provides insights into its adaptation to deep-sea reducing environment
Zhang, L.; He, J.; Tan, P.; Gong, Z.; Qian, S.; Miao, Y.; Zhang, H.-Y.; Chen, Q.; Zhong, Q.; Han, G.; He, J.; Wang, M.
10.1101/2021.09.24.461635 — genomics — Posted on 2021-09-24
939 Expedited gene delivery for osteochondral defect repair in a rabbit knee model: a one-year investigation
Nagelli, C. V.; De La Vega, R. E.; Coenen, M.; Padilla de Lopez, C.; Panos, J. A.; Tovar, A.; Mueller, S. A.; Evans, C. H.
10.1101/2021.09.22.461300 — genetics — Posted on 2021-09-24
940 Zebrafish Information Network, the knowledgebase for Danio rerio research
Bradford, Y. M.; Van Slyke, C. E.; Singer, A.; Paddock, H.; Eagle, A.; Fashena, D.; Howe, D. G.; Frazer, K.; Martin, R.; Pich, C.; Ramachandran, S.; Ruzicka, L.; Westerfield, M.
10.1101/2021.09.22.461443 — genetics — Posted on 2021-09-24
943 Idiosyncratic epistasis leads to global fitness-correlated trends
Bakerlee, C. W.; Nguyen Ba, A. N.; Shulgina, Y.; Rojas-Echenique, J. I.; Desai, M. M.
10.1101/2021.09.22.461382 — evolutionary biology — Posted on 2021-09-24
947 Prescribed versus wildfire impacts on exotic plants and soil microbes in California grasslands
Glassman, S. I.; Randolph, J. W.; Saroa, S. S.; Capocchi, J. K.; Walters, K. E.; Pulido-Chavez, M. F.; Larios, L.
10.1101/2021.09.22.461426 — ecology — Posted on 2021-09-24
949 Maturation of human intestinal epithelium from pluripotency in vitro
Kilik, U.; Yu, Q.; Holtackers, R.; Seimiya, M.; Xavier da Silveira dos Santos, A.; Treutlein, B.; Spence, J. R.; Camp, G.
10.1101/2021.09.24.460132 — cell biology — Posted on 2021-09-24
953 Extrasynaptic signaling enables an asymmetric juvenile motor circuit to produce a symmetric mature gait.
Lu, Y.; Ahamed, T.; Mulcahy, B.; Witvliet, D.; Guan, S. A.; Hung, W.; Meng, J.; Wen, Q.; Samuel, A.; Zhen, M.
10.1101/2021.09.21.461278 — neuroscience — Posted on 2021-09-24
954 Laryngeal and swallow dysregulation following acute cervical spinal cord injury
Pitts, T.; Iceman, K. E.; Huff, A.; Musselwhite, M. N.; Frazure, M. L.; Young, K. C.; Greene, C. L.; Howland, D. R.
10.1101/2021.09.21.457706 — neuroscience — Posted on 2021-09-24
956 Transcranial Focused Ultrasound Neuromodulation of the Thalamic Visual Pathway in a Large Animal Model
Mohammadjavadi, M.; Ash, R. T.; Gaur, P.; Kubanek, J.; Saens, Y.; Glover, G. H.; Popelka, G. R.; Norcia, A. M.; Pauly, K. B.
10.1101/2021.09.21.461109 — neuroscience — Posted on 2021-09-24
957 Modulation of sensory perception by hydrogen peroxide enables Caenorhabditis elegans to find a niche that provides both food and protection from hydrogen peroxide
Schiffer, J. A.; Stumbur, S. V.; Seyedolmohadesin, M.; Xu, Y.; Serkin, W. T.; McGowan, N. G.; Banjo, O.; Torkashvand, M.; Lin, A.; Hosea, C. N.; Assie, A.; Samuel, B. S.; O'Donnell, M. P.; Venkatachalam, V.; Apfeld, J.
10.1101/2021.09.23.461430 — neuroscience — Posted on 2021-09-24
960 Urethane Anesthesia Exhibits Neurophysiological Correlates of Unconsciousness and is Distinct from Sleep
Mondino, A.; Gonzalez, J.; Li, D.; Mateos, D. M.; Osorio, L.; Cavelli, M.; Costa, A.; Vanini, G.; Mashour, G.; Torterolo, P.
10.1101/2021.09.21.461281 — neuroscience — Posted on 2021-09-24
963 Automated 3D reconstruction of the fetal thorax in the standard atlas space from motion-corrupted MRI stacks for 21-36 weeks GA range
Uus, A.; Grigorescu, I.; van Poppel, M. P. M.; Steinweg, J. K.; Roberts, T. A.; Rutherford, M. A.; Hajnal, J. V.; Lloyd, D. F. A.; Pushparajah, K.; Deprez, M.
10.1101/2021.09.22.461335 — bioinformatics — Posted on 2021-09-24
964 Comparison of breeding strategies for the creation of a synthetic pig line
Ganteil, A.; Pook, T.; Rodriguez-Ramilo, S. T.; Ligonesche, B.; Larzul, C.
10.1101/2021.09.22.461330 — genetics — Posted on 2021-09-24
968 Explicit expression of mesophyll conductance in the traditional leaf photosynthesis-transpiration coupled model and its physiological significances
Luo, H.; Carriqui, M.; Nadal, M.; Han, T.; Werner, C.; Huang, J.-f.; Zhang, J.-l.; Yu, Z.-g.; Li, F.-m.; Fang, X.-w.; Xue, W.
10.1101/2021.09.22.461327 — ecology — Posted on 2021-09-24
980 GBRAP: a tool to retrieve, parse and analyze GenBank files of viral and bacterial species
Vischioni, C.; Giaccone, V.; Catellani, P.; Alberghini, L.; Scapin, R. M.; Taccioli, C.
10.1101/2021.09.21.461110 — bioinformatics — Posted on 2021-09-24
982 Bioactive Hydrogel Microcapsules for Guiding Stem Cell Fate Decisions by Release and Reloading of Growth Factors
Revzin, A.; Gwon, K.; Hong, H.; Gonzalez-Suarez, A. M.; Slama, M. Q.; Choi, D.; Hong, J.; Baskaran, H.; Stybayeva, G.; Peterson, Q. P.
10.1101/2021.09.21.461208 — bioengineering — Posted on 2021-09-24
986 Narcolepsy with cataplexy is caused by epigenetic silencing of hypocretin neurons
Seifinejad, A.; Neiteler, A.; Li, S.; Pfister, C.; Fronczek, R.; Shan, L.; Garrett-Sinha, L. A.; Frieser, D.; Honda, M.; Arribat, Y.; Grepper, D.; Amati, F.; Picot, M.; Iseli, C.; Chartre, N.; Lammers, G. J.; Liblau, R.; Vassalli, A.; Tafti, M.
10.1101/2021.09.21.461046 — neuroscience — Posted on 2021-09-24
987 The influence of objecthood on the representation of natural images in the visual cortex
Papale, P.; Zuiderbaan, W.; Teeuwen, R. R. M.; Gilhuis, A.; Self, M. W.; Roelfsema, P. R.; Dumoulin, S. O.
10.1101/2021.09.21.461209 — neuroscience — Posted on 2021-09-24
989 Brain fatty acid binding protein exhibits non-preferential and mutation-resistant binding towards fatty acids
Bodnariuc, I.; Lenz, S.; Renaud-Young, M.; Shandro, T.; Ishida, H.; Vogel, H. J.; MacCallum, J.
10.1101/2021.09.23.461245 — biophysics — Posted on 2021-09-24
991 Identification of microRNAs in the West Nile virus vector Culex tarsalis
Asad, S.; Mehdi, A. M.; Pujhari, S.; Rueckert, C.; Ebel, G. D.; Rasgon, J. L.
10.1101/2021.09.23.461553 — genomics — Posted on 2021-09-24
992 Genetically controlled mtDNA editing prevents ROS damage by arresting oxidative phosphorylation
Stenberg, S.; Li, J.; Gjuvsland, A. B.; Persson, K.; Demitz-Helin, E.; Gonzalez Pena, C.; Yue, J.-X.; Gilchrist, C.; Ärengard, T.; Ghiaci, P.; Larsson-Berglund, L.; Zackrisson, M.; Höög, J. L.; Molin, M.; Liti, G.; Omholt, S. W.; Warringer, J.
10.1101/2020.11.20.391110 — cell biology — Posted on 2021-09-24
993 Population modeling with machine learning can enhance measures of mental health
Dadi, K.; Varoquaux, G.; Houenou, J.; Bzdok, D.; Thirion, B.; Engemann, D. A.
10.1101/2020.08.25.266536 — neuroscience — Posted on 2021-09-24
994 Inhibition of pyrimidine biosynthesis targets protein translation in AML.
Kats, L. M.; So, J.; Lewis, A. C.; Smith, L. K.; Stanley, K.; Pijpers, L.; Dominguez, P.; Hogg, S. J.; Vervoort, S.; Johnstone, R. W.; McDonald, G.; Ulanet, D. B.; Murtie, J.; Gruber, E.
10.1101/2021.09.24.461627 — cancer biology — Posted on 2021-09-24
998 Cooperative Allostery and Structural Dynamics of Streptavidin at Cryogenic- and Ambient-temperature
Ayan, E.; Yuksel, B.; Destan, E.; Ertem, F. B.; Yildirim, G.; Eren, M.; Yefanov, O. M.; Barty, A.; Tolstikova, A.; Ketawala, G. K.; Botha, S.; Dao, E. H.; Hayes, B.; Liang, M.; Seaberg, M. H.; Hunter, M. S.; Batyuk, A.; Mariani, V.; Su, Z.; Poitevin, F.; Yoon, C. H.; Kupitz, C.; Cohen, A.; Doukov, T.; Sierra, R. G.; Dag, C.; DeMirci, H.
10.1101/2021.09.23.461567 — biophysics — Posted on 2021-09-24
999 Probing nanomotion of single bacteria with graphene drums
Roslon, I.; Japaridze, A.; Steeneken, P.; Dekker, C.; Alijani, F.
10.1101/2021.09.21.461186 — biophysics — Posted on 2021-09-24
1000 Brain Injury Localization in Electromagnetic Imaging using Symmetric Crossing Lines Method
Zhu, G.; Bialkowski, A.; Crozier, S.; Guo, L.; Nguyen, P.; Stancombe, A.; Abbosh, A.
10.1101/2021.09.22.461428 — biophysics — Posted on 2021-09-24
1003 Individual repeatability, species differences, and the influence of socio-ecological factors on neophobia in 10 corvid species
Miller, R.; Lambert, M. L.; Frohnwieser, A.; Brecht, K. F.; Bugnyar, T.; Crampton, I.; Garcia-Pelegrin, E.; Gould, K.; Greggor, A. L.; Izawa, E.-I.; Kelly, D. M.; Li, Z.; Luo, Y.; Luong, L. B.; Massen, J. J. M.; Nieder, A.; Reber, S. A.; Schiestl, M.; Seguchi, A.; Sepehri, P.; Stevens, J. R.; Taylor, A. H.; Wang, L.; Wolff, L. M.; Zhang, Y.; Clayton, N. S.
10.1101/2021.07.27.453788 — animal behavior and cognition — Posted on 2021-09-24
1006 The DEAD box RNA helicase DDX42 is an intrinsic inhibitor of positive-strand RNA viruses
Bonaventure, B.; Rebendenne, A.; Garcia de Gracia, F.; McKellar, J.; Gracias, S.; Labaronne, E.; Tauziet, M.; Chaves Valadao, A. L.; Bernard, E.; Briant, L.; Gros, N.; Djilli, W.; Arnaud-Arnould, M.; Courgnaud, V.; Parrinello, H.; Rialle, S.; Schulz, R.; Ricci, E. P.; Jouvenet, N.; Moncorge, O.; Goujon, C.
10.1101/2020.10.28.359356 — microbiology — Posted on 2021-09-24
1007 Genetic basis and dual adaptive role of floral pigmentation in sunflowers
Todesco, M.; Bercovich, N.; Kim, A.; Imerovski, I.; Owens, G. L.; Dorado Ruiz, O.; Holalu, S. V.; Madilao, L. L.; Jahani, M.; Legare, J.-S.; Blackman, B. K.; Rieseberg, L. H.
10.1101/2021.06.26.449999 — evolutionary biology — Posted on 2021-09-24
1008 Sahul's megafauna were vulnerable to plant-community changes due to their position in the trophic network
Llewelyn, J.; Strona, G. S.; McDowell, M.; Johnson, C.; Peters, K.; Stouffer, D. B.; de Visser, S. N.; Saltre, F. B.; Bradshaw, C. J. A.
10.1101/2021.01.19.427338 — ecology — Posted on 2021-09-24
1009 Chromosomal instability mediates immune exclusion and response to cytotoxic chemotherapy in colorectal liver metastases
Martinez, C. A.; Spurr, L. F.; Iyer, S. C.; Pugh, S. A.; Bridgewater, J. A.; Primrose, J. N.; Domingo, E.; Maughan, T. S.; D'Angelica, M. I.; Talamonti, M.; Posner, M. C.; Connell, P. P.; Weichselbaum, R. R.; Pitroda, S. P.
10.1101/2021.09.22.459429 — cancer biology — Posted on 2021-09-23
1010 LncRNA Miat and Metadhedrin maintain a treatment resistant stem-like niche of medulloblastoma cells
Peng, K.-L.; Vasudevan, H. N.; Lockney, D. T.; Baum, R.; Hendrickson, R. C.; Raleigh, D. R.; Schmitt, A. M.
10.1101/2021.09.23.461558 — cancer biology — Posted on 2021-09-24
1011 Multi-context genetic modeling of transcriptional regulation resolves novel disease loci
Thompson, M.; Gordon, M. G.; Lu, A.; Tandon, A.; Halperin, E.; Gusev, A.; Ye, C. J.; Balliu, B.; Zaitlen, N.
10.1101/2021.09.23.461579 — genomics — Posted on 2021-09-23
1012 Tracking extracellular vesicle (EV) cargo as a platform for studying EVomics, signaling, and targeting in vivo
Nikonorova, I. A.; Wang, J.; Cope, A. L.; Tilton, P. E.; Power, K. M.; Walsh, J. D.; Akella, J. S.; Krauchunas, A. R.; Shah, P. R.; Barr, M. M.
10.1101/2021.09.23.461577 — cell biology — Posted on 2021-09-23
1013 Fluctuations in Neural Complexity During Wakefulness Relate To Conscious Level and Cognition
Mediano, P.; Ikkala, A.; Kievit, R. A.; Jagannathan, S. R.; Varley, T. F.; Stamatakis, E. A.; Bekinschtein, T. A.; Bor, D.
10.1101/2021.09.23.461002 — neuroscience — Posted on 2021-09-23
1015 Impedance flow cytometry for viability analysis of Corynebacterium glutamicum
Hartmann, F. S. F.; Anastasiou, I.; Weiss, T.; Shen, J.; Seibold, G. M.
10.1101/2021.09.23.461525 — microbiology — Posted on 2021-09-23
1019 Fatal neuroinvasion and SARS-CoV-2 tropism in K18-hACE2 mice is partially independent on hACE2 expression
Carossino, M.; Montanaro, P.; O'Connell, A.; Kenney, D.; Gertje, H.; Grosz, K.; Ericsson, M.; Huber, B. R.; Subramaniam, S.; Kirkland, T. A.; Walker, J. R.; Francis, K. P.; Klose, A. D.; Paragas, N.; Kurnick, S.; Bosmann, M.; Saeed, M.; Balasuriya, U.; Douam, F.; Crossland, N.
10.1101/2021.01.13.425144 — pathology — Posted on 2021-09-23
1022 Human brain organoid networks
Sharf, T.; van der Molen, T.; Glasauer, S. M. K.; Guzman, E.; Buccino, A. P.; Luna, G.; Cheng, Z.; Audouard, M.; Ranasinghe, K. G.; Kudo, K.; Nagarajan, S. S.; Tovar, K. R.; Petzold, L. R.; Hierlemann, A.; Hansma, P. K.; Kosik, K. S.
10.1101/2021.01.28.428643 — neuroscience — Posted on 2021-09-23
1023 Satellite glia are essential modulators of sympathetic neuron survival, activity, and autonomic function
Mapps, A.; Boehm, E.; Beier, C.; Keenan, W. T.; Langel, J.; Liu, M.; Hattar, S.; Zhao, H.; Tampakakis, E.; Kuruvilla, R.
10.1101/2021.09.23.461591 — neuroscience — Posted on 2021-09-23
1024 Discoidin domain receptor regulates ensheathment, survival, and caliber of peripheral axons
Corty, M. M.; Lassetter, A. P.; Hill, J. Q.; Sheehan, A. E.; Bernardo-Garcia, F. J.; Davis, G. W.; Aicher, S. A.; Freeman, M. R.
10.1101/2021.09.21.461270 — neuroscience — Posted on 2021-09-23
1025 Dysregulated coordination of MAPT exon 2 and exon 10 splicing underlies different tau pathologies in PSP and AD
Bowles, K. R.; Pugh, D. A.; Oja, L.-M.; Jadow, B. M.; Farrell, K.; Whitney, K.; Sharma, A.; Cherry, J.; Raj, T.; Pereira, A.; Crary, J. F.; Goate, A. M.
10.1101/2021.09.23.461598 — neuroscience — Posted on 2021-09-23
1027 Diffusion and distal linkages govern interchromosomal dynamics during meiotic prophase
Newman, T. A.; Beltran, B.; McGehee, J. M.; Elnatan, D.; Cahoon, C. K.; Paddy, M.; Chu, D. B.; Spakowitz, A. J.; Burgess, S. M.
10.1101/2021.04.23.440859 — biophysics — Posted on 2021-09-23
1028 Oligomerization of the FliF domains suggests a coordinated assembly of the bacterial flagellum MS ring
Mariano, G.; Faba-Rodriguez, R.; Bui, S.; Zhao, W.; Ross, J.; Tsokov, S.; Bergeron, J.
10.1101/2021.09.23.461508 — biophysics — Posted on 2021-09-23
1029 Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader
Gaubitz, C.; Liu, X.; Pajak, J.; Stone, N. P.; Hayes, J. A.; Demo, G.; Kelch, B. A.
10.1101/2021.09.23.461575 — biochemistry — Posted on 2021-09-23
1034 NF90 Interacts with Components of RISC and Modulates Association of Ago2 with mRNA
Grasso, G.; Franckhauser, C.; Nait-Saidi, R.; Bello, M.; Barbier, J.; Kiernan, R.
10.1101/2021.09.23.461467 — molecular biology — Posted on 2021-09-23
1040 Nanopore tweezers measurements of RecQ conformational changes reveal the energy landscape of helicase motion
Craig, J. M.; Mills, M.; Laszlo, A.; Kim, H. C.; Abell, S. J.; Huang, J. R.; Mount, J. W.; Neuman, K. C.; Gundlach, J. H.
10.1101/2021.09.23.461529 — biophysics — Posted on 2021-09-23
1041 phastSim: efficient simulation of sequence evolution for pandemic-scale datasets
De Maio, N.; Boulton, W.; Weilguny, L.; Walker, C. R.; Turakhia, Y.; Corbett-Detig, R.; Goldman, N.
10.1101/2021.03.15.435416 — bioinformatics — Posted on 2021-09-23
1042 Privacy Preserving RNA-Model Validation Across Laboratories
Ahmed, T.; Carty, M. A.; Wenric, S.; Dry, J. R.; Salahudeen, A. A.; Khan, A. A.; Lefkofsky, E.; Stumpe, M. C.; Pelossof, R.
10.1101/2021.04.01.437893 — bioinformatics — Posted on 2021-09-23
1043 Peptide fusion improves prime editing efficiency
Velimirovic, M.; Zanetti, L.; Shen, M. W.; Fife, J. D.; Lin, L.; Cha, M.; Akinci, E.; Barnum, D.; Yu, T.; Sherwood, R. I.
10.1101/2021.09.22.461415 — bioengineering — Posted on 2021-09-23
1046 pSNAP: Proteome-wide analysis of elongating nascent polypeptide chains
Uchiyama, J.; Roy, R.; Wang, D. O.; Yoshino, C.; Mishima, Y.; Ishihama, Y.; Imami, K.
10.1101/2021.09.22.461445 — biochemistry — Posted on 2021-09-23
1049 Identification of microRNAs in the West Nile virus vector Culex tarsalis
Asad, S.; Mehdi, A. M.; Pujhari, S.; Ruckert, C.; Ebel, G. D.; Rasgon, J. L.
10.1101/2021.09.23.461553 — genomics — Posted on 2021-09-23
1050 A framework for evaluating edited cell libraries created by massively parallel genome engineering
Cawley, S.; Abbate, E.; Abraham, C. G.; Alvarez, S.; Barber, M.; Bolte, S.; Bruand, J.; Church, D. M.; Davis, C.; Estes, M.; Federowicz, S.; Fox, R.; Gander, M. W.; Garst, A. D.; Gencer, G.; Hardenbol, P.; Hraha, T.; Jain, S.; Johnson, C.; Juneau, K.; Krishnamurthy, N.; Lambert, S.; Leland, B.; Pearson, F.; Ray, J. C. J.; Sanada, C. D.; Shaver, T. M.; Shepherd, T. R.; Spindler, E. C.; Struble, C. A.; Swat, M. H.; Tanner, S.; Tian, T.; Wishart, K.; Graige, M. S.
10.1101/2021.09.23.458228 — genomics — Posted on 2021-09-23
1051 Genetic epidemiology of blood type, disease and trait variants, and genome-wide genetic diversity in over 11,000 domestic cats
Anderson, H.; Davison, S.; Lytle, K. M.; Honkanen, L.; Freyer, J.; Mathlin, J.; Kyöstilä, K.; Inman, L.; Louviere, A.; Chodroff Foran, R.; Forman, O. P.; Lohi, H.; Donner, J.
10.1101/2021.09.06.459083 — genetics — Posted on 2021-09-23
1052 ZAF -- The First Open Source Fully Automated Feeder for Aquatic Facilities
Lange, M.; Solak, A. C.; VijayKumar, S.; Kobayashi, H.; Yang, B.; Royer, L. A.
10.1101/2021.04.28.441879 — developmental biology — Posted on 2021-09-23
1054 Quantification and image-derived phenotyping of retinal ganglion cell nuclei in the nee mouse model of congenital glaucoma
van der Heide, C. J.; Meyer, K. J.; Hedberg-Buenz, A.; Pellack, D.; Pomernackas, N.; Mercer, H. E.; Anderson, M. G.
10.1101/2021.04.13.439698 — molecular biology — Posted on 2021-09-23
1056 Dietary fat promotes antibiotic-induced Clostridioides difficile mortality in mice
Hazleton, K. Z.; Martin, C. G.; Orlicky, D. J.; Arnolds, K. L.; Nusbacher, N. M.; Moreno-Huizar, N.; Armstrong, M. L.; Reisdorph, N.; Lozupone, C. A.
10.1101/828939 — microbiology — Posted on 2021-09-23
1057 Tracing boundaries in Eastern Antarctica: Multi-scale drivers of soil microbial communities across the hyperarid Vestfold Hills
Zhang, E.; Czechowski, P.; Terauds, A.; Wong, S. Y.; Chelliah, D. S.; Raven, M.; Tanaka, M. M.; Ferrari, B. C.
10.1101/2021.09.22.461446 — microbiology — Posted on 2021-09-23
1058 Lipoproteome screening of the Lyme disease agent identifies novel inhibitors of antibody-mediated complement killing
Pereira, M. J.; Wager, B.; Garrigues, R. J.; Gerlach, E.; Quinn, J. D.; Dowdell, A.; Osburne, M. S.; Zuckert, W. R.; Kraiczy, P.; Garcia, B. L.; Leong, J. M.
10.1101/2021.09.23.461563 — microbiology — Posted on 2021-09-23
1059 PplD is a de-N-acetylase of the cell wall linkage unit of streptococcal rhamnopolysaccharides
Rush, J. S.; Parajuli, P.; Ruda, A.; Li, J.; Pohane, A. A.; Zamakhaeva, S.; Rahman, M. M.; Chang, J. C.; Gogos, A.; Kenner, C. W.; Lambeau, G.; Federle, M. J.; Korotkov, K. V.; Widmalm, G.; Korotkova, N.
10.1101/2021.09.23.461590 — microbiology — Posted on 2021-09-23
1061 Effects of bacterial lipopolysaccharide and Shiga Toxin on induced Pluripotent Stem Cell-derived Mesenchymal Stem Cells
Martire-Greco, D.; La Greca, A.; Castillo Montanez, L.; Biani, C.; Lombardi, A.; Birnberg-Weiss, F.; Norris, A.; Sacerdoti, F.; Amaral, M. M.; Rodrigues-Rodriguez, N.; Pittaluga, J. R.; Furmento, V. A.; Landoni, V. I.; Miriuka, S. G.; Luzzani, C. D.; Fernandez, G. C.
10.1101/2021.09.07.459335 — immunology — Posted on 2021-09-23
1062 CAR T cell therapy drives endogenous locoregional T cell dynamics in a responding patient with glioblastoma
Jonsson, V. D.; Ng, R.; Dullerud, N.; Wong, R. A.; Hibbard, J.; Wang, D.; Aguilar, B.; Starr, R.; Weng, L.; Alizadeh, D.; Forman, S.; Badie, B.; Brown, C. E.
10.1101/2021.09.22.460392 — immunology — Posted on 2021-09-23
1063 The rt-TEP tool: real-time visualization of TMS-Evoked Potential to maximize cortical activation and minimize artifacts
Casarotto, S.; Fecchio, M.; Rosanova, M.; Varone, G.; D'Ambrosio, S.; Sarasso, S.; Pigorini, A.; Russo, S.; Comanducci, A.; Ilmoniemi, R. J.; Massimini, M.
10.1101/2021.09.15.460488 — neuroscience — Posted on 2021-09-23
1065 AZBA: A 3D Adult Zebrafish Brain Atlas for the Digital Age
Kenney, J. W.; Steadman, P. E.; Young, O.; Shi, M. T.; Polanco, M.; Dubaishi, S.; Covert, K.; Mueller, T.; Frankland, P. W.
10.1101/2021.05.04.442625 — neuroscience — Posted on 2021-09-23
1067 Evolving a mitigation of the stress response pathway to change the basic chemistry of life
Tolle, I.; Oehm, S.; Hoesl, M. G.; Treiber-Kleinke, C.; Peil, L.; Bukari, A.-R. A.; Semmler, T.; Rappsilber, J.; Gerstein, A.; Budisa, N.
10.1101/2021.09.23.461486 — synthetic biology — Posted on 2021-09-23
1069 Recombinant adenovirus causes prolonged mobilization of macrophages in the anterior chamber of mice
Meyer, K. J.; Pellack, D.; Hedberg-Buenz, A. J.; Pomernackas, N.; Soukup, D.; Wang, K.; Fingert, J. H.; Anderson, M. G.
10.1101/2021.01.13.426423 — physiology — Posted on 2021-09-23
1074 Acute Ketamine Modulated Functional Brain Coupling and Dissociative and Affective States in Human Subjects: Interim Analyses
Hack, L. M.; Warthen, K. G.; Zhang, X.; Heifets, B. D.; Suppes, T.; van Roessel, P.; Rodriguez, C. I.; Knutson, B. D.; Williams, L. M.
10.1101/2021.09.20.460992 — neuroscience — Posted on 2021-09-23
1080 Multiple stressors and recruitment failure of long-lived endangered freshwater mussels with a complex life cycle
Miura, K.; Ishiyama, N.; Negishi, J. N.; Ito, D.; Kawajiri, K.; Izumi, H.; Inoue, T.; Nakaoka, M.; Nakamura, F.
10.1101/2021.09.20.461153 — ecology — Posted on 2021-09-23
1081 Early-life respiratory viral infection results in impairment of adult lung function
Harb, L.; Holt, P. G.; Strickland, D. H.; Martino, D.; Larcombe, A. N.; Bosco, A.
10.1101/2021.09.20.461150 — immunology — Posted on 2021-09-23
1082 Emotion Down- and Up-Regulation Act on Spatially Distinct Brain Areas:Interoceptive Regions to Calm Down and Other Affective Regions to Amp Up
Min, J.; Nashiro, K.; Yoo, H. J.; Cho, C.; Nasseri, P.; Bachman, S. L.; Porat, S.; Thayer, J. F.; Chang, C.; Lee, T.-h.; Mather, M.
10.1101/2021.09.20.461138 — neuroscience — Posted on 2021-09-23
1083 Role of RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer's Disease
Awasthi, S.; Hindle, A.; Sawant, N.; George, M.; Vijayan, M.; Kshirsagar, S.; Morton, H.; Bunquin, L. E.; Palade, P. T.; Lawrence, J. J.; Khan, H.; Bose, C.; Reddy, P. H. H.; Singh, S. P.
10.1101/2021.09.20.461132 — neuroscience — Posted on 2021-09-23
1084 Extracellular Vesicles Carry Distinct Proteo-Transcriptomic Signatures That are Different from Their Cancer Cell of Origin
Chen, T.-y.; Gonzalez-Kozlova, E.; Soleymani, T.; La Salvia, S.; Kyprianou, N.; Sahoo, S.; Tewari, A.; Cordon-cardo, C.; Stolovitzky, G.; Dogra, N.
10.1101/2021.09.20.460963 — bioinformatics — Posted on 2021-09-23
1085 Context-aware deconvolution of cell-cell communication with Tensor-cell2cell
Armingol, E.; Baghdassarian, H.; Martino, C.; Perez-Lopez, A.; Knight, R.; Lewis, N. E.
10.1101/2021.09.20.461129 — bioinformatics — Posted on 2021-09-23
1088 A Cellular Reference Resource for the Mouse Urinary Bladder
Baker, D.; Al-Naggar, I. M.; Sivajothi, S.; Flynn, W. F.; Amiri, A.; Luo, D.; Hardy, C. C.; Kuchel, G. A.; Smith, P. P.; Robson, P.
10.1101/2021.09.20.461121 — genomics — Posted on 2021-09-23
1089 Plant host shift: The viability and persistence of a polyphagous non-native insect
Bueno Silva, I.; McGrane-Corrigan, B.; Mason, O.; de Andrade Moral, R.; Augusto Conde Godoy, W.
10.1101/2021.09.20.461112 — ecology — Posted on 2021-09-23
1094 Image model embeddings for digital pathology and drug development via self-supervised learning
baykaner, k.; xu, m.; bordeaux, l.; gu, f.; selvaraj, b.; gaffney, i.; dillon, l.; hipp, j.
10.1101/2021.09.20.461088 — bioinformatics — Posted on 2021-09-23
1095 Identifying The "Core" Transcriptome of SARS-CoV-2 Infected Cells
Nour, E. T.; Tran, R.; Afravi, A.; Pei, X.; Davidian, A.; Kadandale, P.
10.1101/2021.09.22.461142 — bioinformatics — Posted on 2021-09-23
1100 Lung epithelial CYP1 activity regulates aryl hydrocarbon receptor dependent allergic airway inflammation
Alessandrini, F.; de Jong, R.; Wimmer, M.; Maier, A.-M.; Fernandez, I.; Hils, M.; Buters, J.; Biedermann, T.; Zissler, U.; Hoffmann, C.; Esser-von-Bieren, J.; Schmidt-Weber, C. B.; Ohnmacht, C.
10.1101/2021.09.20.461064 — immunology — Posted on 2021-09-23
1105 Top2a promotes the development of social behavior via PRC2 and H3K27me3
Geng, Y.; Zhang, T.; Godar, S. C.; Pluimer, B. R.; Harrison, D. L.; Nath, A. K.; Yeh, J.-R. J.; Drummond, I. A.; Bortolato, M.; Peterson, R. T.
10.1101/2021.09.20.461107 — animal behavior and cognition — Posted on 2021-09-23
1107 A Purkinje cell to parabrachial nucleus pathway enables broad cerebellar influence over the forebrain and emotional valence
Chen, C. H.; Newman, L. N.; Stark, A. P.; Bond, K. E.; Zhang, D.; Mutume, K.; Flaquer, I.; Regehr, W. G.
10.1101/2021.09.21.461236 — neuroscience — Posted on 2021-09-23
1109 Confined migration induces heterochromatin formation and alters chromatin accessibility
Hsia, C.-R.; McAllister, J.; Hasan, O.; Judd, J.; Lee, S.; Agrawal, R.; Chang, C.-Y.; Soloway, P.; Lammerding, J.
10.1101/2021.09.22.461293 — cell biology — Posted on 2021-09-23
1110 Hyperglycemia-induced alteration of ER redox homeostasis delays ER export of proinsulin
Rohli, K. E.; Boyer, C. K.; Bearrows, S. C.; Moyer, M. R.; Elison, W. S.; Bauchle, C. J.; Blom, S. E.; Yu, C.-L.; Pope, M. R.; Zhang, J.; Wang, Y.; Stephens, S. B.
10.1101/2021.09.22.461417 — cell biology — Posted on 2021-09-23
1111 The connection between Rap1 and Talin1 in CD4+ T Lymphocytes
Lagarrigue, F.; Tan, B.; Du, Q.; Fan, Z.; Lopez-Ramirez, M. A.; Gingras, A. R.; Qi, W.; Sun, H.
10.1101/2021.09.22.461411 — cell biology — Posted on 2021-09-23
1113 Mechanosensitive control of mitotic entry
Dantas, M.; Oliveira, A.; Aguiar, P.; Maiato, H.; Ferreira, J. G.
10.1101/2021.09.23.461473 — cell biology — Posted on 2021-09-23
1114 Assessment of community efforts to advance computational prediction of protein-protein interactions
Wang, X.-W.; Madeddu, L.; Spirohn, K.; Martini, L.; Fazzone, A.; Becchetti, L.; Wytock, T. P.; Kovacs, I. A.; Balogh, O. M.; Benczik, B.; Petervari, M.; Agg, B.; Ferdinandy, P.; Vulliard, L.; Menche, J.; Colonnese, S.; Petti, M.; Scarano, G.; Cuomo, F.; Hao, T.; Laval, F.; Willems, L.; Twizere, J.-C.; Calderwood, M.; Petrillo, E.; Barabasi, A.-L.; Silverman, E. K.; Loscalzo, J.; Velardi, P.; Liu, Y.-Y.
10.1101/2021.09.22.461292 — systems biology — Posted on 2021-09-23
1115 Computationally designed GPCR quaternary structures bias signaling pathway activation
Paradis, J. S.; Feng, X.; Murat, B.; Jefferson, R. E.; Szpakowska, M. E.; Hogue, M.; Bergkamp, N. D.; Heidenreich, F. M.; Smit, M. J.; Chevigne, A.; Bouvier, M.; Barth, P.
10.1101/2021.09.23.461493 — biophysics — Posted on 2021-09-23
1118 A novel view on the mechanism of biological activity of antifreeze proteins
Melnik, B. S.; Glukhova, K. A.; Sokolova, E. A.; Balalaeva, I. V.; Finkelstein, A. V.
10.1101/2021.09.22.461391 — biophysics — Posted on 2021-09-23
1122 Glucosyltransferase-dependent and independent effects of Clostridioides difficile toxins during infection
Peritore-Galve, F. C.; Shupe, J. A.; Cave, R. J.; Washington, M. K.; Kuehne, S. A.; Lacy, D. B.
10.1101/2021.09.22.460915 — pathology — Posted on 2021-09-23
1124 Learning about threat from friends and strangers is equally effective: an fMRI study on observational fear conditioning
Kazmierowska, A. M.; Szczepanik, M.; Wypych, M.; Drozdziel, D.; Marchewka, A.; Michalowski, J. M.; Olsson, A.; Knapska, E.
10.1101/2021.09.20.461036 — neuroscience — Posted on 2021-09-23
1126 Multi-locus transcranial magnetic stimulation system for electronically targeted brain stimulation
Nieminen, J. O.; Sinisalo, H.; Souza, V. H.; Malmi, M.; Yuryev, M.; Tervo, A. E.; Stenroos, M.; Milardovich, D.; Korhonen, J. T.; Koponen, L. M.; Ilmoniemi, R. J.
10.1101/2021.09.20.461045 — neuroscience — Posted on 2021-09-23
1130 ProMetheusDB: an in-depth analysis of the high-quality human methyl-proteome
Massignani, E.; Giambruno, R.; Maniaci, M.; Nicosia, L.; Yadav, A.; Cuomo, A.; Raimondi, F.; Bonaldi, T.
10.1101/2021.09.20.461082 — bioinformatics — Posted on 2021-09-23
1131 DeNovoCNN: A deep learning approach to de novo variant calling in next generation sequencing data
Khazeeva, G.; Sablauskas, K.; van der Sanden, B.; Steyaert, W.; Kwint, M.; Rots, D.; Hinne, M.; van Gerven, M.; Yntema, H.; Vissers, L.; Gilissen, C.
10.1101/2021.09.20.461072 — bioinformatics — Posted on 2021-09-23
1132 Sensing Local Field Potentials with a Directional and Scalable Depth Array: DISC
Mancilla, A. A.; Khan, W.; Wright, C. E.; Prajapati, N.; Islam, M. R.; Bai, X.; Ghajar, M. H.; Tandon, N.; Seymour, J.
10.1101/2021.09.20.460996 — bioengineering — Posted on 2021-09-23
1134 Differential use of multiple genetic sex determination systems in divergent ecomorphs of an African crater lake cichlid
Munby, H.; Linderoth, T.; Fischer, B.; Du, M.; Vernaz, G.; Tyers, A. M.; Ngatunga, B. P.; Shechonge, A.; Denise, H.; McCarthy, S. A.; Bista, I.; Miska, E. A.; Santos, M. E.; Genner, M. J.; Turner, G. F.; Durbin, R.
10.1101/2021.08.05.455235 — evolutionary biology — Posted on 2021-09-23
1135 Regulation of immune receptor kinases plasma membrane nanoscale landscape by a plant peptide hormone and its receptors
Gronnier, J.; Franck, C. M.; Stegmann, M.; DeFalco, T.; Abarca, A.; Von Arx, M.; Duenser, K.; Lin, W.; Yang, Z.; Kleine-Vehn, J.; Ringli, C.; zipfel, c.
10.1101/2020.07.20.212233 — plant biology — Posted on 2021-09-23
1136 Virtual Mouse Brain Histology from Multi-contrast MRI via Deep Learning
Liang, Z.; Lee, C. H.; Arefin, T. M.; Dong, Z.; Walczak, P.; Shi, S.-H.; Knoll, F.; Ge, Y.; Ying, L.; Zhang, J.
10.1101/2020.05.01.072561 — bioengineering — Posted on 2021-09-23
1137 Interferon induction and not replication interference mainly determines anti-influenza virus activity of defective interfering particles
Arora, P.; Bdeir, N.; Gärtner, S.; Reiter, S.; Pelz, L.; Felgenhauer, U.; Reichl, U.; Ludwig, S.; Weber, F.; Hoffmann, M.; Winkler, M.; Pöhlmann, S. H.
10.1101/2021.09.20.461172 — molecular biology — Posted on 2021-09-23
1138 Carbapenem-Resistant Acinetobacter baumannii in US hospitals: diversification of circulating lineages and antimicrobial resistance
Iovleva, A. V.; Mustapha, M. M.; Griffith, M. P.; Komarow, L.; Luterbach, C.; Evans, D. R.; Cober, E.; Richter, S. S.; Rydell, K.; Arias, C. A.; Jacob, J. T.; Salata, R. A.; Satlin, M. J.; Wong, D.; Bonomo, R. A.; van Duin, D.; Cooper, V. S.; Van Tyne, D.; Doi, Y.
10.1101/2021.09.21.461323 — microbiology — Posted on 2021-09-23
1139 Functional and Structural Characterization of OXA-935, a Novel OXA-10-family β-lactamase from Pseudomonas aeruginosa
Pincus, N. B.; Rosas-Lemus, M.; Gatesy, S. W.; Shuvalova, L. A.; Brunzelle, J.; Minasov, G. A.; Satchell, K. J. F.; Lebrun-Corbin, M.; Ozer, E. A.; Hauser, A. R.; Bachta, K. E. R.
10.1101/2021.09.20.461173 — microbiology — Posted on 2021-09-23
1140 Protective transfer: Maternal passive immunization with a rotavirus-neutralizing dimeric IgA protects against rotavirus disease in suckling neonates
Langel, S. N.; Steppe, J. T.; Chang, J.; Travieso, T.; Webster, H.; Otero, C.; Williamson, L.; Crowe, J. E.; Greenberg, H.; Wu, H.; Hornik, C.; Mansouri, K.; Edward, R.; Stalls, V.; Acharya, P.; Blasi, M.; Permar, S. R.
10.1101/2021.09.21.461116 — immunology — Posted on 2021-09-23
1142 KMT2D Loss Promotes Head and Neck Squamous Cell Carcinoma Through Enhancer Reprogramming and Modulation of Immune Microenvironment
Callahan, S. C.; Divenko, M.; Barrodia, P.; Singh, A. K.; Arslan, E.; Liu, Z.; Yang, J.; Anvar, N.; Amit, M.; Xie, T.; Jiang, S.; Schulz, J.; Tang, M.; Myers, J. N.; Rai, K.
10.1101/2021.09.21.461314 — cancer biology — Posted on 2021-09-23
1143 Multi-modal profiling of the extracellular matrix of human fallopian tubes and serous tubal Intraepithelial carcinomas
Renner, C.; Gomez, C.; Visetsouk, M. R.; Taha, I. N.; Khan, A.; McGregor, S.; Weisman, P.; Naba, A.; Masters, K. S.; Kreeger, P. K.
10.1101/2021.09.21.461246 — cancer biology — Posted on 2021-09-23
1145 Single-cell genetic heterogeneity linked to immune infiltration in glioblastoma.
Walentynowicz, K. A.; Engelhardt, D.; Yadav, S.; Onubogu, U.; Salatino, R.; Vincentelli, C.; McDonald, T. O.; Michor, F.; Janiszewska, M.
10.1101/2021.09.20.461080 — cancer biology — Posted on 2021-09-23
1147 The WRAD complex represents a therapeutically exploitable target for cancer stem cells in glioblastoma
Mitchell, K.; Shakya, S.; Silver, D. J.; Goins, C. M.; Wallace, L.; Roversi, G.; Schafer, R.; Kay, K.; Miller, T. E.; Lauko, A.; Kass, J. D.; Kashyap, A.; Mulkearns-Hubert, E. E.; Johnson, S.; Alvarado, J.; Rich, J. N.; Stauffer, S. R.; Hubert, C. G.; Lathia, J. D.
10.1101/2021.09.20.461125 — cancer biology — Posted on 2021-09-23
1148 Uterus-specific transcriptional regulation underlies eggshell pigment production in Japanese quail
Ishishita, S.; Kitahara, S.; Takahashi, M.; Iwasaki, S.; Tatsumoto, S.; Hara, I.; Kaneko, Y.; Kinoshita, K.; Yamaguchi, K.; Harada, A.; Ohmori, Y.; Ohkawa, Y.; Go, Y.; Shigenobu, S.; Matsuda, Y.; Suzuki, T.
10.1101/2021.09.15.460419 — genetics — Posted on 2021-09-23
1149 Unidirectional ion transport mechanism of a light-driven chloride pump revealed using X-ray free electron lasers
Hosaka, T.; Nomura, T.; Kubo, M.; Nakane, T.; Fangjia, L.; Sekine, S.-i.; Ito, T.; Murayama, K.; Ihara, K.; Ehara, H.; Kashiwagi, K.; Katsura, K.; Akasaka, R.; Hisano, T.; Tanaka, T.; Tanaka, R.; Arima, T.; Yamashita, A.; Sugahara, M.; Naitow, H.; Matsuura, Y.; Yoshizawa, S.; Tono, K.; Owada, S.; Nureki, O.; Kimura-Someya, T.; Iwata, S.; Nango, E.; Shirouzu, M.
10.1101/2021.09.21.461290 — molecular biology — Posted on 2021-09-23
1150 Sugar beet cold-induced PMT5a and STP13 carriers are poised for taproot proton-driven plasma membrane sucrose and glucose import
Reyer, A.; Bazihizina, N.; Scherzer, S.; Jaslan, J.; Schäfer, N.; Jaslan, D.; Cuin, T. A.; Al-Rasheid, K. A. S.; Alfarhan, A. H.; Alquraishy, S. A.; Ludewig, F.; Koch, W.; Harms, K.; Becker, D.; Müller, T. D.; Pommerrenig, B.; Neuhaus, H. E.; Marten, I.; Hedrich, R.
10.1101/2021.09.21.461191 — plant biology — Posted on 2021-09-23
1155 Uncovering the Genetic Profiles Underlying the Intrinsic Organization of the Human Cerebellum
Wang, Y.; Chai, L.; Li, D.; Gao, C.; Chu, C.; Yang, Z.; Zhang, Y.; Xu, J.; Nyengaard, J. R.; Eickhoff, S. B.; Liu, B.; Madsen, K. H.; Jiang, T.; Fan, L.
10.1101/2021.06.23.448673 — neuroscience — Posted on 2021-09-23
1161 Initial contact shapes the perception of friction
Willemet, L.; Kanzari, K.; Monnoyer, J.; Birznieks, I.; Wiertlewski, M.
10.1101/2021.09.20.461039 — biophysics — Posted on 2021-09-22
1162 Detection of m6A from direct RNA sequencing using a Multiple Instance Learning framework
Hendra, C.; Pratanwanich, P. N.; Wan, Y. K.; Goh, W. S. S.; Thiery, A.; Goeke, J.
10.1101/2021.09.20.461055 — bioinformatics — Posted on 2021-09-22
1166 Cerebrospinal fluid amyloid beta and glial fibrillary acidic protein concentrations in Huntingtons disease
Korpela, S.; Sundblom, J.; Zetterberg, H.; Constantinescu, R.; Svenningsson, P.; Paucar, M.; Niemelä, V.
10.1101/2021.09.22.461351 — neuroscience — Posted on 2021-09-22
1168 Anti-Bat Ultrasound Production in Moths is Globally and Phylogenetically Widespread
Barber, J. R.; Plotkin, D.; Rubin, J. J.; Homziak, N. T.; Leavell, B. C.; Houlihan, P.; Miner, K. A.; Breinholt, J. W.; Quirk-Royal, B.; Padron, P. S.; Nunez, M.; Kawahara, A. Y.
10.1101/2021.09.20.460855 — evolutionary biology — Posted on 2021-09-22
1171 A different mechanism of C-type inactivation in the Kv-like KcsA mutant E71V
Rohaim, A.; Vermeulen, B.; Li, J.; Kummerer, F.; Napoli, F.; Blachowicz, L.; Medeiros-Silva, J.; Roux, B.; Weingarth, M.
10.1101/2021.09.22.461404 — molecular biology — Posted on 2021-09-22
1172 Novel Hendra virus variant detected by sentinel surveillance of Australian horses.
Annand, E. J.; Horsburgh, B. A.; Xu, K.; Reid, P. A.; Poole, B.; de Kantzow, M. C.; Brown, N.; Tweedie, A.; Michie, M.; Grewar, J. D.; Jackson, A. E.; Singanallur, N. B.; Plain, K. M.; Kim, K.; Tachedjian, M.; van der Heide, B.; Crameri, S.; Williams, D. T.; Secombe, C.; Laing, E. D.; Sterling, S.; Yan, L.; Jackson, L.; Jones, C.; Plowright, R. K.; Peel, A. J.; Breed, A. C.; Diallo, I.; Dhand, N. K.; Britton, P. N.; Broder, C. C.; Smith, I.; Eden, J.-S.
10.1101/2021.07.16.452724 — molecular biology — Posted on 2021-09-22
1175 Astrocytic C-X-C motif chemokine ligand-1 mediates β-amyloid-induced tau mislocalization and synaptotoxicity
Perez-Nievas, B. G.; Johnson, L.; Beltran-Lobo, P.; Hughes, M. M.; Gammallieri, L.; Tarsitano, F.; Myszczynska, M. A.; Vazquez-Villasenor, I.; Jimenez-Sanchez, M.; Troakes, C.; Wharton, S. B.; Ferraiuolo, L.; Noble, W.
10.1101/2021.09.22.458716 — neuroscience — Posted on 2021-09-22
1176 The 22q11.2 region regulates presynaptic gene-products linked to schizophrenia
Nehme, R.; Pietilainen, O.; Artomov, M.; Tegtmeyer, M.; Bell, C.; Ganna, A.; Singh, T.; Trehan, A.; Valakh, V.; Sherwood, J.; Manning, D.; Peirent, E.; Malik, R.; Guss, E. J.; Hawes, D.; Beccard, A.; Bara, A. M.; Hazelbaker, D. Z.; Zuccaro, E.; Genovese, G.; Loboda, A. A.; Neumann, A.; Lilliehook, C.; Kuismin, O.; Hamalainen, E.; Kurki, M.; Hultman, C. M.; Kahler, A. K.; Paulo, J. A.; Madison, J.; Cohen, B.; McPhie, D.; Adolfsson, R.; Perlis, R.; Dolmetsch, R.; Farhi, S.; McCarroll, S.; Hyman, S.; Neale, B.; Barrett, L. E.; Harper, W.; Palotie, A.; Daly, M.; Eggan, K.
10.1101/2021.09.22.461360 — neuroscience — Posted on 2021-09-22
1177 Identification of touch neurons underlying dopaminergic pleasurable touch and sexual receptivity
Middleton, L.; Schaffler, M.; Succi, I.; Foster, W.; Gradwell, M.; Bohic, M.; Ejoh, L.; Abraira, V.; Abdus-Saboor, I.
10.1101/2021.09.22.461355 — neuroscience — Posted on 2021-09-22
1178 High Enhancer Activity is an Epigenetic Feature of HPV Negative Atypical Head and Neck Squamous Cell Carcinoma
Callahan, S. C.; Kochat, V.; Liu, Z.; Raman, A. T.; Schulz, J.; Terranova, C.; Divenko, M.; Ghosh, A.; Tang, M.; Pickering, C.; Myers, J. N.; Rai, K.
10.1101/2021.09.21.461310 — cancer biology — Posted on 2021-09-22
1179 Ion currents through Kir potassium channels are gated by anionic lipids.
Jin, R.; He, S.; Black, K. A.; Clarke, O. B.; Wu, D.; Bolla, J. R.; Johnson, P.; Periasamy, A.; Wardak, A.; Czabotar, P.; Colman, P. M.; Robinson, C. V.; Laver, D.; Smith, B. J.; Gulbis, J. M.
10.1101/2021.09.21.461288 — biochemistry — Posted on 2021-09-22
1181 Complex population structure and haplotype patterns in Western Europe honey bee from sequencing a large panel of haploid drones
Wragg, D.; Eynard, S. E.; Basso, B.; Canale-Tabet, K.; Labarthe, E.; Bouchez, O.; Bienefeld, K.; Bienkowska, M.; Costa, C.; Gregorc, A.; Kryger, P.; Parejo, M.; Pinto, M. A.; Bidanel, J.-P.; Servin, B.; Le Conte, Y.; Vignal, A.
10.1101/2021.09.20.460798 — genetics — Posted on 2021-09-22
1182 Combinatorial G x G x E CRISPR screening and functional analysis highlights SLC25A39 in mitochondrial GSH transport
Shi, X.; Reinstadler, B.; Shah, H.; To, T.-L.; Byrne, K.; Summer, L.; Calvo, S. E.; Goldberger, O.; Doench, J. G.; Mootha, V. K.; Shen, H.
10.1101/2021.09.22.461361 — cell biology — Posted on 2021-09-22
1183 A new paradigm for leprosy diagnosis based on host gene expression
Leal-Calvo, T.; Avanzi, C.; Mendes, M. A.; Benjak, A.; Busso, P.; Pinheiro, R. O.; Sarno, E. N.; Cole, S. T.; Moraes, M. O.
10.1101/2021.07.30.454441 — molecular biology — Posted on 2021-09-22
1184 Unidirectional ion transport mechanism of a light-driven chloride pump revealed using X-ray free electron lasers
Hosaka, T.; Nomura, T.; Kubo, M.; Nakane, T.; Fangjia, L.; Sekine, S.-i.; Ito, T.; Murayama, K.; Ihara, K.; Ehara, H.; Kashiwagi, K.; Katsura, K.; Akasaka, R.; Hisano, T.; Tanaka, T.; Tanaka, R.; Arima, T.; Yamashita, A.; Sugahara, M.; Naitow, H.; Matsuura, Y.; Yoshizawa, S.; Tono, K.; Owada, S.; Nureki, O.; Kimura-Someya, T.; Iwata, S.; Nango, E.; Shirouzu, M.
10.1101/2021.09.21.461290 — molecular biology — Posted on 2021-09-22
1186 Elucidating spatially-resolved changes in host signaling during Plasmodium liver-stage infection
Glennon, E. K.; Tongogara, T.; Primavera, V. I.; Reeder, S. M.; Wei, L.; Kaushansky, A.
10.1101/2021.09.22.461346 — microbiology — Posted on 2021-09-22
1188 Minor variants of swine H1N1 influenza viruses with enhanced polymerase activity and HA stability promote airborne transmission in ferrets
Hu, M.; Jones, J.; Banoth, B.; Ojha, C. R.; Crumpton, J. C.; Kercher, L.; Webster, R. G.; Webby, R. J.; Russell, C. J.
10.1101/2021.09.22.461336 — microbiology — Posted on 2021-09-22
1190 A curcumin direct protein (DiPro) biosensor for cell-free prototyping
Lesniewska, A.; Griffin, G.; Freemont, P. K.; Polizzi, K. M.; Moore, S. J.
10.1101/2021.09.22.461347 — synthetic biology — Posted on 2021-09-22
1191 Sequential rescue and repair of stalled and damaged ribosome by bacterial PrfH and RtcB
Tian, Y.; Zeng, F.; Raybarman, A.; Carruthers, A.; Li, Q.; Fatma, S.; Huang, R. H.
10.1101/2021.09.22.461353 — biochemistry — Posted on 2021-09-22
1192 Structural Insights into Bifunctional Thaumarchaeal Crotonyl-CoA Hydratase and 3-Hydroxypropionyl-CoA Dehydratase from Nitrosopumilus maritimus
Destan, E.; Yuksel, B.; Tolar, B. B.; Ayan, E.; Deutsch, S.; Yoshikuni, Y.; Wakatsuki, S.; Francis, C. A.; DeMirci, H.
10.1101/2021.09.22.461329 — biochemistry — Posted on 2021-09-22
1194 Nonsense-associated alternative splicing as a putative reno-protective mechanism in Pkhd1cyli/Pkhd1cyli mutant mice
Yang, C.; Harafuji, N.; Odinakashukwu, M. C.; Caldovic, L.; Boddu, R.; Gordish-Dressman, H.; Foreman, O.; Eicher, E. M.; Guay-Woodford, L.
10.1101/2021.09.22.461297 — genetics — Posted on 2021-09-22
1197 Nano3P-seq: transcriptome-wide analysis of gene expression and tail dynamics using end-capture nanopore sequencing
Begik, O.; Liu, H.; Delgado-Tejedor, A.; Kontur, C.; Giraldez, A. J.; Beaudoin, J.-D.; Mattick, J. S.; Novoa, E. M.
10.1101/2021.09.22.461331 — molecular biology — Posted on 2021-09-22
1198 Functional study of Leishmania braziliensis protein arginine methyltransferases (PRMTs) reveals that PRMT1 and PRMT5 are required for macrophage infection
Lorenzon, L.; Quilles, J. C.; Campagnaro, G. D.; Almeida, L.; Veras, F. P.; Magalhaes, R. D. M.; Alcoforado Diniz, J.; Ferreira, T. R.; Cruz, A. K.
10.1101/2021.09.22.461376 — molecular biology — Posted on 2021-09-22
1199 Mosaic Evolution of Beta Barrel Porin Encoding Genes in Escherichia coli
Chen, X.; Cai, X.; Chen, Z.; Wu, J.; Hao, G.; Luo, Q.; Zhu, G.; Koester, W.; White, A. P.; Cai, Y.; Wang, Y.
10.1101/2021.09.21.461324 — microbiology — Posted on 2021-09-22
1200 Recombinant Fasciola hepatica fatty acid binding protein (Fh15) as a novel anti-inflammatory biotherapeutic in an acute gram-negative non-human primate sepsis model
Rosado-Franco, J. J.; Armina-Rodriguez, A.; Marzan-Rivera, N.; Burgos, A.; Spiliopoulos, N.; Dorta-Estremera, S. M.; Mendez, L. B.; Espino, A. M.
10.1101/2021.09.21.461321 — microbiology — Posted on 2021-09-22
1202 A new oomycete metabarcoding method using the rps10 gene
Foster, Z. S. L.; Albornoz, F. E.; Fieland, V. J.; Larsen, M. M.; Jones, F. A.; Tyler, B. M.; Nguyen, H. D. T.; Burgess, T. I.; Riddell, C.; Voglmayr, H.; Martin, F. N.; Grunwald, N. J.
10.1101/2021.09.22.460084 — microbiology — Posted on 2021-09-22
1205 Predicting the evolution of Lassa Virus endemic area and population at risk over the next decades
Klitting, R.; Kafetzopoulou, L. E.; Thiery, W.; Dudas, G.; Gryseels, S.; Kotamarthi, A.; Vrancken, B.; Gangavarapu, K.; Momoh, M.; Demby Sandy, J.; Goba, A.; Alhasan, F.; Grant, D. S.; Garry, R. F.; Smither, A. R.; Zeller, M.; Pauthner, M. G.; McGraw, M.; Hughes, L. D.; Duraffour, S.; Gunther, S.; Suchard, M. A.; Lemey, P.; Andersen, K. G.; Dellicour, S.
10.1101/2021.09.22.461380 — microbiology — Posted on 2021-09-22
1209 Real-Time, Direct Classification of Nanopore Signals with SquiggleNet
Bao, Y.; Wadden, J.; Erb-Downward, J. R.; Ranjan, P.; Zhou, W.; McDonald, T. L.; Mills, R. E.; Boyle, A. P.; Dickson, R. P.; Blaauw, D.; Welch, J. D.
10.1101/2021.01.15.426907 — bioinformatics — Posted on 2021-09-22
1220 Dynamic regulation and requirement for ribosomal RNA transcription duringmammalian development
Terrazas Falcon, K.; Watt, K.; Dash, S.; Achilleos, A.; Moore, E.; Zhao, R.; Fitriasari, S.; Sakai, D.; Childers, M.; Sardiu, M.; Swanson, S.; Tsuchiya, D.; Unruh, J.; Bugarinovic, G.; Li, L.; Shiang, R.; Dixon, J.; Dixon, M.; Trainor, P.
10.1101/2021.09.22.461379 — developmental biology — Posted on 2021-09-22
1221 Epithelial Plasticity and Innate Immune Activation Promote Lung Tissue Remodeling following Respiratory Viral Infection.
Beppu, A.; Zhao, J.; Yao, C.; Carraro, G.; Israely, E.; Coelho, A. L.; Hogaboam, C. M.; Parks, W. C.; Kolls, J. K.; Stripp, B. R.
10.1101/2021.09.22.461381 — cell biology — Posted on 2021-09-22
1223 Mechanical stimulation promotes enthesis injury repair by mobilizing Prx1+ cells via ciliary TGF-β signaling
Xiao, H.; Zhang, T.; Li, C. J.; Cao, Y.; Wang, L. F.; Chen, H. B.; Li, S. C.; Guan, C. B.; Hu, J. Z.; Chen, D.; Chen, C.; Lu, H. B.
10.1101/2021.09.21.461317 — cell biology — Posted on 2021-09-22
1226 High-resolution imaging and manipulation of endogenous AMPA receptor surface mobility during synaptic plasticity and learning
Getz, A. M.; Ducros, M.; Breillat, C.; Lampin-Saint-Amaux, A.; Daburon, S.; Francois, U.; Nowacka, A.; Fernandez-Monreal, M.; Hosy, E.; Lanore, F.; Zieger, H.; Sainlos, M.; Humeau, Y.; Choquet, D.
10.1101/2021.09.21.461215 — neuroscience — Posted on 2021-09-22
1230 Cell-surface tethered promiscuous biotinylators enable small-scale surface proteomics of human exosomes
Kirkemo, L. L.; Elledge, S.; Yang, J.; Byrnes, J. R.; Glasgow, J. E.; Blelloch, R.; Wells, J. A.
10.1101/2021.09.22.461393 — biochemistry — Posted on 2021-09-22
1232 SNP and Haplotype Regional Heritability Mapping (SNHap-RHM): joint mapping of common and rare variation affecting complex traits
Oppong, R. F.; Boutin, T.; Campbell, A.; McIntosh, A. M.; Porteous, D.; Hayward, C.; Haley, C. S.; Navarro, P.; Knott, S.
10.1101/2021.08.02.454788 — genomics — Posted on 2021-09-22
1234 Core cysteine residues in the PAN domain are critical for HGF/c-MET signaling
Pal, D.; De, K.; Shanks, C. M.; Feng, K.; Yates, T. B.; Morrell-Falvey, J.; Davidson, R. B.; Parks, J. M.; Muchero, W.
10.1101/2021.09.20.460979 — cell biology — Posted on 2021-09-22
1240 Object manifold geometry across the mouse cortical visual hierarchy
Froudarakis, E.; Cohen, U.; Diamantaki, M.; Walker, E. Y.; Reimer, J.; Berens, P.; Sompolinsky, H.; Tolias, A. S.
10.1101/2020.08.20.258798 — neuroscience — Posted on 2021-09-22
1245 Sequestration of RBM10 in Nuclear Bodies: Targeting Sequences and Biological Significance
Wang, L.-Y.; Xiao, S.-J.; Kunimoto, H.; Tokunaga, K.; Kojima, H.; Kimura, M.; Yamamoto, T.; Yamamoto, N.; Hong, Z.; Nishio, K.; Tani, T.; Nakajima, K.; Sunami, K.; Inoue, A.
10.1101/516831 — molecular biology — Posted on 2021-09-22
1254 Harvesting electrical current from intact plant leaves
Shlosberg, Y.; Meirovitch, M.; Yehezkeli, O.; Schuster, G.; Adir, N.
10.1101/2021.09.19.460952 — bioengineering — Posted on 2021-09-22
1258 Identification of topoisomerase as a precision-medicine target in chromatin reader SP140-driven Crohns disease
Amatullah, H.; Digumarthi, S.; Fraschilla, I.; Adiliaghdam, F.; Bonilla, G.; Wong, L. P.; Sadreyev, R.; Jeffrey, K. L.
10.1101/2021.09.20.461083 — immunology — Posted on 2021-09-22
1259 Decoding subjective emotional arousal from EEG during an immersive Virtual Reality experience
Hofmann, S. M.; Klotzsche, F.; Mariola, A.; Nikulin, V. V.; Villringer, A.; Gaebler, M.
10.1101/2020.10.24.353722 — neuroscience — Posted on 2021-09-22
1262 Balancing growth amidst salinity stress-lifestyle perspectives from the extremophyte model Schrenkiella parvula
Tran, K.-N.; Pantha, P.; Wang, G.; Kumar, N.; Wijesinghege, C.; Oh, D.-H.; Duppen, N.; He, J.; Li, H.; Hong, H.; Johnson, J. C.; Kelt, R.; Matherne, M. G.; Clement, A.; Tran, D.; Crain, C.; Adhikari, P.; Zhang, Y.; Foroozani, M.; Sessa, G.; Larkin, J. C.; Smith, A. P.; Longstreth, D.; Finnegan, P.; Testerink, C.; Barak, S.; Dassanayake, M.
10.1101/2021.08.27.457575 — plant biology — Posted on 2021-09-22
1265 Low membrane fluidity triggers lipid phase separation and protein segregation in vivo
Gorhbandt, M.; Lipski, A.; Grimshaw, J. W.; Buttress, J. A.; Baig, Z.; Herkenhoff, B.; Walter, S.; Kurre, R.; Deckers-Hebestreit, G.; Strahl, H.
10.1101/852160 — microbiology — Posted on 2021-09-22
1266 Cross-dataset reproducibility of human retinotopic maps
Himmelberg, M. M.; Kurzawski, J. W.; Benson, N. C.; Pelli, D. G.; Carrasco, M.; Winawer, J.
10.1101/2021.04.12.439348 — neuroscience — Posted on 2021-09-22
1268 Sugar beet cold-induced PMT5a and STP13 carriers are poised for taproot proton-driven plasma membrane sucrose and glucose import
Reyer, A.; Bazihizina, N.; Scherzer, S.; Jaslan, J.; Schäfer, N.; Jaslan, D.; Cuin, T. A.; Al-Rasheid, K. A. S.; Alfarhan, A. H.; Alquraishy, S. A.; Ludewig, F.; Koch, W.; Harms, K.; Becker, D.; Müller, T. D.; Pommerrenig, B.; Neuhaus, H. E.; Marten, I.; Hedrich, R.
10.1101/2021.09.21.461191 — plant biology — Posted on 2021-09-22
1269 Locally adapted oak populations along an elevation gradient display different molecular strategies to regulate bud phenology.
Le Provost, G.; Lalanne, C.; Lesur, I.; Louvet, J.-M.; Delzon, S.; Kremer, A.; Labadie, K.; Aury, J.-M.; Da Silva, C.; Plomion, C.
10.1101/2021.09.21.461210 — plant biology — Posted on 2021-09-22
1270 Cryptic pathogen-sugar interactions revealed by universal saturation transfer analysis
Buchanan, C. J.; Gaunt, B.; Harrison, P. J.; Yang, Y.; Liu, J.; Khan, A.; Giltrap, A. M.; Le Bas, A.; Ward, P. N.; Gupta, K.; Dumoux, M.; Daga, S.; Picchiotti, N.; Baldassarri, M.; Benetti, E.; Fallerini, C.; Fava, F.; Giliberti, A.; Koukos, P. I.; Lakshminarayanan, A.; Xue, X.; Papadakis, G.; Deimel, L. P.; Casablancas-Antras, V.; Claridge, T. D. W.; Bonvin, A. M. J. J.; Sattentau, Q. J.; Furini, S.; Gori, M.; Huo, J.; Owens, R. J.; Schaffitzel, C.; Berger, I.; Renieri, A.; GEN-COVID Multicenter Study, ; Naismith, J. H.; Baldwin, A.; Davis, B. G.
10.1101/2021.04.14.439284 — biophysics — Posted on 2021-09-22
1271 Development of lipidoid nanoparticles for siRNA delivery to neural cells
Khare, P.; Dave, K. M.; Kamte, Y. S.; Manoharan, M. A.; O'Donnell, L. A.; Manickam, D. S.
10.1101/2021.07.28.454207 — bioengineering — Posted on 2021-09-22
1273 Pathological LSD1 mutations repress enhancer-mediated gene regulatory networks in early differentiation
Bunina, D.; Germain, P.-L.; Lopez Tobon, A.; Fernandez-Novel Marx, N.; Arnold, C.; Ahern, A.; Claringbould, A.; Lai, M. C.; Rangasamy, S.; Narayanan, V.; Lorentzen, P.; Park, K. M.; Adamo, A.; Testa, G.; Zaugg, J. B.; Noh, K.-M.
10.1101/2021.08.11.455900 — genomics — Posted on 2021-09-22
1275 Assessing the impact of grassland management on landscape multifunctionality
Neyret, M.; Fischer, M.; Allan, E.; Hoelzel, N.; Klaus, V.; Kleinebecker, T.; Krauss, J.; Le Provost, G.; Peter, S.; Schenk, N.; Simons, N. K.; van der Plas, F.; Binkenstein, J.; Boerschig, C.; Jung, K.; Prati, D.; Schaefer, D.; Schaefer, M.; Schoening, I.; Schrumpf, M.; Tschapka, M.; Westphal, C.; Manning, P.
10.1101/2020.07.17.208199 — ecology — Posted on 2021-09-22
1276 Analysis of the upper respiratory tract microbiota in mild and severe COVID-19 patients
Babenko, V. V.; Bakhtyev, R. R.; Baklaushev, V. P.; Balykova, L. A.; Bashkirov, P. V.; Bespyatykh, J. A.; Blagonravova, A. S.; Boldyreva, D. I.; Fedorov, D. E.; Gafurov, I. R.; Gaifullina, R. F.; Galeeva, J. S.; Galova, E. A.; Gospodaryk, A. V.; Ilina, E. N.; Ivanov, K. P.; Kharlampieva, D. D.; Khromova, P. A.; Klimina, K. M.; Kolontarev, K. B.; Kolyshkina, N. A.; Koritsky, A. V.; Kuropatkin, V. A.; Lazarev, V. N.; Manolov, A. I.; Manuvera, V. A.; Matyushkina, D. S.; Morozov, M. D.; Moskaleva, E. V.; Musarova, V. A.; Ogarkov, O. B.; Orlova, E. A.; Pavlenko, A. V.; Petrova, A. G.; Pozhenko, N.
10.1101/2021.09.20.461025 — molecular biology — Posted on 2021-09-22
1277 Virucidal activity of CPC-containing oral rinses against SARS-CoV-2 variants and are active in the presence of human saliva
Anderson, E. R.; Patterson, E. I.; Richards, S.; Green, A. K.; Mukherjee, S.; Hoptroff, M.; Hughes, G.
10.1101/2021.08.05.455040 — microbiology — Posted on 2021-09-22
1280 Decline in constitutive proliferative activity in the zebrafish retina with ageing
Hernandez-Nunez, I.; Quelle-Regaldie, A.; Sanchez, L.; Adrio, F.; Candal, E.; Barreiro-Iglesias, A.
10.1101/2021.06.16.448637 — neuroscience — Posted on 2021-09-22
1285 Genomic epidemiology of Mycobacterium bovis infection in sympatric badger and cattle populations in Northern Ireland.
Akhmetova, A.; Guerrero, J.; McAdam, P.; Salvador, L. C. M.; Crispell, J.; Lavery, J.; Presho, E.; Kao, R. R.; Biek, R.; Menzies, F.; Trimble, N.; Harwood, R.; Pepler, T.; Oravcova, K.; Graham, J.; Skuce, R. A.; du Plessis, L. R.; Thompson, S.; Wright, L.; Byrne, A. W.; Allen, A. R.
10.1101/2021.03.12.435101 — evolutionary biology — Posted on 2021-09-22
1286 Calpain DEK1 acts as a developmental switch gatekeeping cell fate transitions
Demko, V.; Belova, T.; Messerer, M.; Hvidsten, T. R.; Perroud, P.-F.; Ako, A. E.; Johansen, W.; Mayer, K. F. X.; Olsen, O.-A.; Lang, D.
10.1101/2021.08.25.457637 — developmental biology — Posted on 2021-09-22
1287 Galvanic current activates the NLRP3 inflammasome to promote type I collagen production in tendon
Penin-Franch, A.; Garcia-Vidal, J. A.; Martinez, C. M.; Escolar-Reina, P.; Gomez, A. I.; Minaya-Munoz, F.; Valera-Garrido, F.; Medina-Mirapeix, F.; Pelegrin, P.
10.1101/2021.09.20.461048 — immunology — Posted on 2021-09-22
1291 A uniform benchmark for testing ssrA-derived degrons in the Escherichia coli ClpXP pathway
Gorna, M. W.; Klimecka, M. M.; Antosiewicz, A.; Izert, M. A.; Szybowska, P. E.; Twardowski, P. K.; Delaunay, C.
10.1101/2021.08.26.457770 — biochemistry — Posted on 2021-09-22
1292 Landscape connectivity alters the evolution of density-dependent dispersal during pushed range expansions
Dahirel, M.; Bertin, A.; Calcagno, V.; Duraj, C.; Fellous, S.; Groussier, G.; Lombaert, E.; Mailleret, L.; Marchand, A.; Vercken, E.
10.1101/2021.03.03.433752 — ecology — Posted on 2021-09-22
1297 A novel anti-influenza combined therapy assessed by single cell RNA-sequencing
Medaglia, C.; Kolpakov, I.; Zhu, Y.; Constant, S.; Huang, S.; Zwygart, A. C.-A.; Cagno, V.; Dermitzakis, E.; Stellacci, F.; Xenarios, I.; Tapparel, C.
10.1101/2021.07.27.453967 — genomics — Posted on 2021-09-22
1298 Flexible fitting of PROTAC concentration-response curves with changepoint Gaussian Processes
Semenova, E.; Guerriero, M. L.; Zhang, B.; Hock, A.; Hopcroft, P.; Kadamur, G.; Afzal, A. M.; Lazic, S. E.
10.1101/2020.11.13.379883 — cell biology — Posted on 2021-09-22
1299 The Telomere Length Landscape of Prostate Cancer
Livingstone, J.; Shiah, Y.-J.; Yamaguchi, T. N.; Heisler, L. E.; Huang, V.; Lesurf, R.; Gebo, T.; Carlin, B.; Eng, S.; Drysdale, E.; Green, J.; van der Kwast, T.; Bristow, R. G.; Fraser, M.; Boutros, P. C.
10.1101/2021.05.22.445239 — genomics — Posted on 2021-09-22
1301 DNA dynamics dictates p53 functional outcome
Safieh, J.; Chazan, A.; Vyas, P.; Saleem, H.; Danin-Poleg, Y.; Ron, D.; Haran, T. E.
10.1101/2021.09.18.460898 — biochemistry — Posted on 2021-09-22
1304 Identification of topoisomerase as a precision-medicine target in chromatin reader SP140-driven Crohns disease
Amatullah, H.; Digumarthi, S.; Fraschilla, I.; Adiliaghdam, F.; Bonilla, G.; Wong, L. P.; Sadreyev, R.; Jeffrey, K. L.
10.1101/2021.09.20.461083 — immunology — Posted on 2021-09-21
1305 Almost nontoxic tetrodotoxin analog, 5,6,11-trideoxytetrodotoxin, as an olfactory chemoattractant for the grass puffer
Noguchi, Y.; Suzuki, T.; Matsutani, K.; Nakahigashi, R.; Satake, Y.; Adachi, M.; Nishikawa, T.; Abe, H.
10.1101/2021.09.12.459881 — zoology — Posted on 2021-09-21
1307 LM-GVP: A Generalizable Deep Learning Framework for Protein Property Prediction from Sequence and Structure
Wang, Z.; Combs, S. A.; Brand, R.; Calvo, M. R.; Xu, P.; Price, G.; Golovach, N.; Salawu, E. O.; Wise, C. J.; Ponnapalli, S. P.; Clark, P. M.
10.1101/2021.09.21.460852 — synthetic biology — Posted on 2021-09-21
1309 DNA motif analysis of shear stress responsive endothelial enhancers reveals differential association of KLF and ETV/ETS binding sites with gained and lost enhancers
Siekmann, A. F.; Tsaryk, R.; Yucel, N.; Arany, Z.; Bondareva, O.; Schnittler, H.; Odenthal-Schnittler, M.; Leonard, E.; Diaz, N.; Vaquerizas, J. M.
10.1101/2021.09.21.460846 — genomics — Posted on 2021-09-21
1314 Nuclear Pore Complex Acetylation Regulates mRNA Export and Cell Cycle Commitment in Budding Yeast
Gomar-Alba, M.; Pozharskaia, V.; Schaal, C.; Kumar, A.; Jacquel, B.; Charvin, G.; Igual, J. C.; Mendoza, M.
10.1101/2021.09.01.458533 — cell biology — Posted on 2021-09-21
1318 BehaviorDEPOT: a tool for automated behavior classification and analysis in rodents
Gabriel, C. J.; Zeidler, Z.; Jin, B.; Guo, C.; Wu, A.; Delaney, M.; Cheung, J.; DiFazio, L. E.; Sharpe, M. J.; Aharoni, D.; Wilke, S. A.; DeNardo, L. A.
10.1101/2021.06.20.449150 — neuroscience — Posted on 2021-09-21
1320 The rt-TEP tool: real-time visualization of TMS-evoked potentials to maximize cortical activation and minimize artifacts
Casarotto, S.; Fecchio, M.; Rosanova, M.; Varone, G.; D'Ambrosio, S.; Sarasso, S.; Pigorini, A.; Russo, S.; Comanducci, A.; Ilmoniemi, R. J.; Massimini, M.
10.1101/2021.09.15.460488 — neuroscience — Posted on 2021-09-21
1321 Reactivating Hippocampal-Mediated Memories to Disrupt the Reconsolidation of Fear
Grella, S. L.; Fortin, A. H.; Bladon, J. H.; Reynolds, L. F.; Ruesch, E.; Gross, A.; Shpokayte, M.; Cincotta, C.; Zaki, Y.; Ramirez, S.
10.1101/2021.09.16.460695 — neuroscience — Posted on 2021-09-21
1322 Fate transitions in Drosophila neural lineages: a single cell road map to mature neurons.
Marques, G. S.; Teles-Reis, J.; Konstantinides, N.; Brito, P. H.; Homem, C. C. F.
10.1101/2021.06.22.449317 — neuroscience — Posted on 2021-09-21
1324 Network potential identifies therapeutic miRNA cocktails in Ewings Sarcoma
Weaver, D. T.; Pishas, K. I.; Williamson, D.; Scarborough, J.; Lessnick, S. L.; Dhawan, A.; Scott, J. G.
10.1101/854695 — systems biology — Posted on 2021-09-21
1326 GPER-dependent estrogen signaling increases cardiac GCN5L1 expression and MCAD activity
Manning, J. R.; Thapa, D.; Zhang, M.; Stoner, M. W.; Sembrat, J. C.; Rojas, M.; Scott, I.
10.1101/2021.09.20.461099 — physiology — Posted on 2021-09-21
1327 Characterisation of tumour immune microenvironment remodelling following oncogene inhibition in preclinical studies using an optimised imaging mass cytometry workflow
van Maldegem, F.; Valand, K.; Cole, M.; Patel, H.; Angelova, M.; Rana, S.; Colliver, E.; Enfield, K.; Bah, N.; Tsang, V.; Mugarza, E.; Moore, C.; Hobson, P.; Levi, D.; Molina, M.; Swanton, C.; Downward, J.
10.1101/2021.02.02.429358 — cancer biology — Posted on 2021-09-21
1328 Somatic Mutations in Collagens are Associated with a Distinct Tumor Environment and Overall Survival in Gastric Cancer
Brodsky, A. S.; Khurana, J.; Guo, K.; Wu, E. Y.; Yang, D.; Siddique, A. S.; Wong, I. Y.; Uzun, E. D.; Resnick, M. B.
10.1101/2021.01.19.426938 — cancer biology — Posted on 2021-09-21
1329 Proton export drives the Warburg Effect
Russell, S.; Xu, L.; Kam, Y.; Abrahams, D.; Ordway, B.; Lopez, A.; Bui, M. M.; Johnson, J.; Epstein, T.; Ruiz, E.; Lloyd, M.; Swietach, P.; Verduzco, D.; Wojtkowiak, J.; Gillies, R.
10.1101/2021.09.20.461019 — cancer biology — Posted on 2021-09-21
1331 Cryo-electron tomography reveals structural insights into the membrane binding and remodeling activity of dynamin-like EHDs
Melo, A. A.; Sprink, T.; Noel, J.; Vazquez Sarandeses, E.; van Hoorn, C.; Loerke, J.; M.T. Spahn, C.; Daumke, O.
10.1101/2021.09.20.461157 — biophysics — Posted on 2021-09-21
1340 High Resolution Ancestry Deconvolution for Next Generation Genomic Data
Hilmarsson, H.; Kumar, A. S.; Rastogi, R.; Bustamante, C. D.; Mas Montserrat, D.; Ioannidis, A. G.
10.1101/2021.09.19.460980 — genomics — Posted on 2021-09-21
1346 The Integrator complex regulates microRNA abundance through RISC loading
Kirstein, N.; Dokaneheifard, S.; Reddy Cingaram, P.; Valencia, M. G.; Beckedorff, F.; Gomes Dos Santos, H.; Blumenthal, E.; Tayari, M. M.; Shiekhattar, R.
10.1101/2021.09.21.461113 — molecular biology — Posted on 2021-09-21
1350 Cryptococcus neoformans releases proteins during intracellular residence that affect the outcome of the fungal-macrophage interaction
Jung, E. H.; Park, Y.-D.; Dragotakes, Q.; Ramirez, L. S.; Smith, D. F.; Dziedzic, A.; Williamson, P. R.; Jedlicka, A.; Casadevall, A.; Coelho, C.
10.1101/2021.09.21.461206 — microbiology — Posted on 2021-09-21
1352 Macrophages transfer mitochondria to neurons to resolve inflammatory pain
van der Vlist, M.; Raoof, R.; Willemen, H. L. D. M.; Prado, J.; Versteeg, S.; Martin Gil, C.; Vos, M.; Lokhorst, R. E.; Pasterkamp, R. J.; Kojima, T.; Karasuyama, H.; Khoury-Hanold, W.; Meyaard, L.; Eijkelkamp, N.
10.1101/2020.02.12.940445 — neuroscience — Posted on 2021-09-21
1353 NPAS4 in the medial prefrontal cortex mediates chronic social defeat stress- induced anhedonia and dendritic spine loss
Hughes, B. W.; Siemsen, B. M.; Berto, S.; Kumar, J.; Cornbrooks, R. G.; Akiki, R. M.; Carter, J. S.; Scofield, M. D.; Cowan, C. W.; Taniguchi, M.
10.1101/2021.03.04.433930 — neuroscience — Posted on 2021-09-21
1356 Gut markers of bodily self-consciousness
Monti, A.; Porciello, G.; Panasiti, M. S.; Aglioti, S. M.
10.1101/2021.03.05.434072 — physiology — Posted on 2021-09-21
1357 Loss of Fgfr1 and Fgfr2 in Scleraxis-lineage cells leads to enlarged bone eminences and attachment cell death
Wernle, K. K.; Sonnenfelt, M. A.; Leek, C. C.; Ganji, E.; Tata, Z.; Offutt, C.; Paparella, E.; Shuff, J.; Sullivan, A. L.; Ornitz, D. M.; Killian, M. L.
10.1101/2021.09.20.461087 — physiology — Posted on 2021-09-21
1358 Ligand binding remodels protein side chain conformational heterogeneity
Wankowicz, S. A.; de Oliveira, S. H. P.; Hogan, D. W.; van den Bedem, H.; Fraser, J. S.
10.1101/2021.09.21.461269 — biophysics — Posted on 2021-09-21
1360 Structure of the Shaker Kv channel and mechanism of slow C-type inactivation
Tan, X.-F.; Bae, C.; Stix, R.; Fernandez-Marino, A. I.; Huffer, K.; Chang, T.-H.; Jiang, J.; Faraldo-Gomez, J.; Swartz, K. J.
10.1101/2021.09.21.461258 — biophysics — Posted on 2021-09-21
1361 Investigation of the impact of stool collection methods on the metabolomics analysis/profiles of infant fecal samples
Homann, C.-M.; Dizzell, S.; Azab, S.; Hutton, E. K.; GI-MDH Consortium, ; Morrison, K. M.; Stearns, J. C.
10.1101/2021.09.21.461251 — biochemistry — Posted on 2021-09-21
1363 Probing differences in gene essentiality between the human and animal adapted lineages of the Mycobacterium tuberculosis complex using TnSeq
Gibson, A. J.; Passmore, I. J.; Faulkner, V.; Xia, D.; Nobeli, I.; Stiens, J.; Willcocks, S.; Werling, D.; Villarreal-Ramos, B.; Wren, B. W.; Kendall, S. L.
10.1101/2021.09.21.461195 — microbiology — Posted on 2021-09-21
1364 A BioID-derived proximity interactome for SARS-CoV-2 proteins
May, D. G.; Martin-Sancho, L.; Anschau, V.; Liu, S.; Chrisopulos, R. J.; Scott, K. L.; Halfmann, C. T.; Pena, R. D.; Pratt, D.; Campos, A. R.; Roux, K. J.
10.1101/2021.09.17.460814 — molecular biology — Posted on 2021-09-21
1365 SARS-CoV-2 preS dTM vaccine booster candidates increase functional antibody responses and cross-neutralization against SARS-CoV-2 variants of concern in non-human primates
Pavot, V.; Berry, C.; Kishko, M.; Anosova, N. G.; Huang, D.; Tibbitts, T.; Raillard, A.; Gautheron, S.; Gutzeit, C.; Koutsoukos, M.; Chicz, R. M.; Lecouturier, V.
10.1101/2021.09.20.461023 — immunology — Posted on 2021-09-21
1367 Mechanistic Insights into the Effects of Key Mutations on SARS-CoV-2 RBD-ACE2 Binding
Aggarwal, A.; Naskar, S.; Maroli, N.; Gorai, B.; Dixit, N. M.; Maiti, P. K.
10.1101/2021.09.20.461041 — biophysics — Posted on 2021-09-21
1368 An integrated view of baseline protein expression in human tissues
Prakash, A.; Garcia-Seisdedos, D.; Wang, S.; Kundu, D. J.; Collins, A.; George, N.; Moreno, P.; Papatheodorou, I.; Jones, A. R.; Vizcaino, J. A.
10.1101/2021.09.10.459811 — bioinformatics — Posted on 2021-09-21
1370 Global distribution of the rooting zone water storage capacity reflects plant adaptation to the environment
Stocker, B. D.; Tumber-Davila, S. J.; Konings, A. G.; Anderson, M. B.; Hain, C.; Jackson, R. B.
10.1101/2021.09.17.460332 — ecology — Posted on 2021-09-21
1373 What is unique about the human eye? Comparative image analysis on the external eye morphology of human and nonhuman great apes
Kano, F.; Furuichi, T.; Hashimoto, C.; Krupenye, C.; Leinwand, J. G.; Hopper, L. M.; Martin, C. F.; Otsuka, R.; Tajima, T.
10.1101/2021.09.21.461196 — animal behavior and cognition — Posted on 2021-09-21
1377 Self-organized emergence of hyaline cartilage in hiPSC-derived multi-tissue organoids
Li, M.; Abrahante, J. E.; Vegoe, A.; Chai, Y. W.; Lindborg, B.; Toth, F.; Larsen, P. A.; O'Brien, T. D.
10.1101/2021.09.21.461213 — cell biology — Posted on 2021-09-21
1378 HCN2 in cholinergic interneurons of the nucleus accumbens mediates reward response
Lee, J.; Weinberger, M.; Kawahara, Y.; Cheng, J.; Umscweif, G.; Medrihan, L.; Flajolet, M.; Nishi, A.; Sagi, Y.
10.1101/2021.09.21.460269 — neuroscience — Posted on 2021-09-21
1382 Transitioning to confined spaces impacts bacterial swimming and escape response
Lynch, J. B.; James, N.; McFall-Ngai, M.; Ruby, E. G.; Shin, S.; Takagi, D.
10.1101/2021.09.15.460467 — biophysics — Posted on 2021-09-21
1385 Admp regulates tail bending by controlling the intercalation of the ventral epidermis through myosin phosphorylation.
Kogure, Y. S.; Muraoka, H.; Koizumi, W. C.; Gelin-alessi, R.; Godard, B.; Heisenberg, C.-P.; Oka, K.; Hotta, K.
10.1101/2021.09.21.461063 — developmental biology — Posted on 2021-09-21
1386 PCDH7 Promotes Cell Migration by Regulating Myosin Activity
Qureshi, M. H.; Cinko, M. T.; Bayraktar, H.; Akkaya, C.; Kamacioglu, A.; Uretmen, Z. C.; Bozluolcay, E.; Ozlu, N.
10.1101/2021.09.21.460794 — cell biology — Posted on 2021-09-21
1387 Opening the side exit pores of ClpP by lowering the pH of proteolytic chamber coupled with substrate hydrolysis
Kim, L.; Lee, B.-G.; Kim, M. K.; Kwon, D. H.; Kim, H.; Bröz-Oesterhelt, H.; roh, S.-H.; Song, H. K.
10.1101/2021.09.20.461017 — biochemistry — Posted on 2021-09-21
1388 Molecular insights into RNA recognition and gene regulation by the TRIM-NHL protein Mei-P26
Salerno-Kochan, A.; Horn, A.; Ghosh, P.; Nithin, C.; Ko?cielniak, A.; Strauss, D.; Rossbach, O.; Bujnicki, J. M.; Gaik, M.; Medenbach, J.; Glatt, S.
10.1101/2021.09.20.461029 — biochemistry — Posted on 2021-09-21
1389 A genetic compensatory mechanism regulated by c-Jun and Mef2d modulates the expression of distinct class IIa HDACs to ensure peripheral nerve myelination and repair
Cabedo, H.; Velasco-Aviles, S.; Patel, N.; Casillas-Bajo, A.; Frutos-Rincon, L.; Velasco-Serna, E.; Gallar, J.; Arthur-Farraj, P.; Gomez-Sanchez, J. A.
10.1101/2021.09.20.461026 — cell biology — Posted on 2021-09-21
1392 Broadband Signal Rather than Frequency-Specific Rhythms Underlie Prediction Error in the Primate Auditory Cortex
Canales-Johnson, A.; Teixeira Borges, A. F.; Komatsu, M.; Fujii, N.; Fahrenfort, J. J.; Miller, K. J.; Noreika, V.
10.1101/821942 — neuroscience — Posted on 2021-09-21
1394 Different DGAT1s show different TAG synthesis abilities and a specific amino acid substitution enhances oil accumulation
Hatanaka, T. N.; Tomita, Y.; Mtsuoka, D.; Sasayama, D.; Fukayama, H. N.; Azuma, T.; Soltani Gishini, M. F.; Hildebrand, D.
10.1101/2021.09.19.461007 — plant biology — Posted on 2021-09-21
1396 Tig1 regulates proximo-distal identity during salamander limb regeneration
Oliveira, C. R.; Knapp, D.; Elewa, A.; Gerber, T.; Gonzalez Malagon, S. G.; Gates, P. B.; Walters, H. E.; Petzold, A.; Arce, H.; Cordoba, R.; Subramanian, E.; Chara, O.; Tanaka, E. M.; Simon, A.; Yun, M.
10.1101/2021.02.03.428234 — developmental biology — Posted on 2021-09-21
1398 Distinct ground state and activated state modes of spiking in forebrain neurons
Levenstein, D.; Girardeau, G.; Gornet, J.; Grosmark, A.; Huszar, R.; Peyrache, A.; Senzai, Y.; Watson, B.; Rinzel, J.; Buzsaki, G.
10.1101/2021.09.20.461152 — neuroscience — Posted on 2021-09-21
1401 Functional network topography of the medial entorhinal cortex
Obenhaus, H. A.; Zong, W.; Jacobsen, R. I.; Rose, T.; Donato, F.; Chen, L.; Cheng, H.; Bonhoeffer, T.; Moser, M.-B.; Moser, E. I.
10.1101/2021.09.20.461016 — neuroscience — Posted on 2021-09-21
1404 Amyloid β oligomer selective antibodies for Alzheimers therapeutics and diagnostics
Viola, K. L.; Bicca, M. A.; Bebenek, A. M.; Kranz, D. L.; Nandwana, V.; Waters, E. A.; Haney, C. R.; Lee, M.; Gupta, A.; Brahmbhatt, Z.; Huang, W.; Chang, T.-T.; Peck, A.; Valdez, C.; Dravid, V. P.; Klein, W. L.
10.1101/2021.09.20.460817 — neuroscience — Posted on 2021-09-21
1406 Large-scale two-photon calcium imaging in freely moving mice
Zong, W.; Obenhaus, H. A.; Skytoen, E. R.; Eneqvist, H.; Jong, N. L. d.; Jorge, M. R.; Moser, M.-B.; Moser, E. I.
10.1101/2021.09.20.461015 — neuroscience — Posted on 2021-09-21
1407 Efficient ancestry and mutation simulation with msprime 1.0
Baumdicker, F.; Bisschop, G.; Goldstein, D.; Gower, G.; Ragsdale, A. P.; Tsambos, G.; Zhu, S.; Eldon, B.; Ellerman, C. E.; Galloway, J. G.; Gladstein, A. L.; Gorjanc, G.; Guo, B.; Jeffery, B.; Kretzschmar, W. W.; Lohse, K.; Matschiner, M.; Nelson, D.; Pope, N. S.; Quinto-Cortes, C. D.; Rodrigues, M. F.; Saunack, K.; Sellinger, T.; Thornton, K.; van Kemenade, H.; Wohns, A. W.; Wong, Y.; Gravel, S.; Kern, A. D.; Koskela, J.; Ralph, P. L.; Kelleher, J.
10.1101/2021.08.31.457499 — genetics — Posted on 2021-09-21
1414 Coral: a web-based visual analysis tool for creating and characterizing cohorts
Adelberger, P.; Eckelt, K.; Bauer, M. J.; Streit, M.; Haslinger, C.; Zichner, T.
10.1101/2021.05.26.445802 — bioinformatics — Posted on 2021-09-21
1415 Diversity and distribution of sediment bacteria across an ecological and trophic gradient
Sauer, H. M.; Hamilton, T. L.; Anderson, R. E.; Umbanhowar, C. E.; Heathcote, A. J.
10.1101/2021.09.20.461123 — ecology — Posted on 2021-09-20
1416 Cryo-electron tomography of ASC signalling sites in pyroptotic cells
Liu, Y.; Zhai, H.; Alemayehu, H.; Hopkins, L. J.; Borgeaud, A. C.; Heroven, C.; Howe, J. D.; Boulanger, J.; Bryant, C. E.; Modis, Y.
10.1101/2021.09.20.461078 — immunology — Posted on 2021-09-20
1417 Comparison of two injectable anaesthetic protocols in Egyptian fruit bats (Rousettus aegyptiacus) undergoing gonadectomy
Amari, M.; Brioschi, F. A.; Rabbogliatti, V.; Di Cesare, F.; Pecile, A.; Giordano, A.; Moretti, P.; Magnone, W.; Bonato, F.; Ravasio, G.
10.1101/2021.09.20.461052 — zoology — Posted on 2021-09-20
1421 A conformational switch controlling the toxicity of the prion protein
Frontzek, K.; Bardelli, M.; Senatore, A.; Henzi, A.; Reimann, R. R.; Bedir, S.; Marino, M.; Hussain, R.; Jurt, S.; Meisl, G.; Pedotti, M.; Mazzola, F.; Siligardi, G.; Zerbe, O.; Knowles, T. P. J.; Lakkaraju, A.; Zhu, C.; Schwarz, P.; Hornemann, S.; Holt, M. G.; Simonelli, L.; Varani, L.; Aguzzi, A.
10.1101/2021.09.20.460912 — molecular biology — Posted on 2021-09-20
1423 Loss of Fgfr1 and Fgfr2 in Scleraxis-lineage cells leads to enlarged bone eminences and attachment cell death
Shuff, J.; Offutt, C.; Killian, M. L.; Ornitz, D. M.; Leek, C. C.; Ganji, E.; Tata, Z.; Paparella, E.; Sonnenfelt, M. A.; Sullivan, A. L.; Wernle, K. K.
10.1101/2021.09.20.461087 — physiology — Posted on 2021-09-20
1424 Synergic Renoprotective Effects Of Combined ASC Therapy With RAAS Blockade In Experimental Advanced CKD
Maires, M. P.; Pereira, K. R.; Silva, E. K.; Souza, V. H.; Teles, F.; Barbosa, P. F.; Garnica, M. R.; Ornellas, F. M.; Noronha, I. L.; Fanelli, C.
10.1101/2021.09.20.461095 — physiology — Posted on 2021-09-20
1428 New Insights into the Mechanisms Used by Inhibitors Targeting Glutamine Metabolism in Cancer Cells
Milano, S. K.; Huang, Q.; Nguyen, T.-T. T.; Ramachandran, S.; Finke, A.; Kriksunov, I.; Schuller, D.; Szebenyi, M.; Arenholz, E.; McDermott, L. A.; Sukumar, N.; Cerione, R. A.; Katt, W. P.
10.1101/2021.09.20.461106 — biochemistry — Posted on 2021-09-20
1429 A simple immunoassay for extracellular vesicle liquid biopsy in microliters of non-processed plasma
Campos-Silva, C.; Caceres-Martell, Y.; Sanchez-Herrero, E.; Sandua Condado, A.; Beneitez-Martinez, A.; Gonzalez Hernandez, A.; Provencio, M.; Romero, A.; Jara Acevedo, R.; Yanez-Mo, M.; Vales-Gomez, M.
10.1101/2021.09.20.461033 — biochemistry — Posted on 2021-09-20
1430 Acoustic Force Spectroscopy Reveals Subtle Differences in Cellulose Unbinding Behavior of Carbohydrate-Binding Modules
Hackl, M.; Contrada, E. V.; Ash, J. E.; Kulkarni, A.; Yoon, J.; Cho, H.-Y.; Lee, K.-B.; Yarbrough, J. M.; Chundawat, S. P. S.
10.1101/2021.09.20.461102 — biochemistry — Posted on 2021-09-20
1435 Progenitor-intrinsic Metabolic Sensing Promotes Hematopoietic Homeostasis
Pizzato, H. A.; Wang, Y.; Wolfgang, M.; Finck, B.; Patti, G. J.; Bhattacharya, D.
10.1101/2021.09.20.461098 — developmental biology — Posted on 2021-09-20
1436 TGS1: a novel regulator of β-cell mass and function
Blandino-Rosano, M.; Romaguera-Llacer, P.; Lin, A.; Reddy, J. K.; Bernal-Mizrachi, E.
10.1101/2021.09.20.461105 — cell biology — Posted on 2021-09-20
1438 RNA polymerase II dynamics and mRNA stability feedback determine mRNA scaling with cell size
Swaffer, M. P.; Marinov, G. K.; Zheng, H.; Jones, A. W.; Kundaje, A.; Snijders, A. P.; Greenleaf, W. J.; Reyes-Lamothe, R.; Skotheim, J. M.
10.1101/2021.09.20.461005 — molecular biology — Posted on 2021-09-20
1442 Dormant phages communicate to control exit from lysogeny
Aframian, N.; Omer Bendori, S.; Hen, S.; Guler, P.; Stokar-Avihail, A.; Manor, E.; Msaeed, k.; Lipsman, V.; Grinberg, I.; Mahagna, A.; Eldar, A.
10.1101/2021.09.20.460909 — microbiology — Posted on 2021-09-20
1443 Oxidized thioredoxin-1 restrains the NLRP1 inflammasome
Ball, D. P.; Wang, A. E.; Warren, C. D.; Wang, Q.; Griswold, A. R.; Rao, S. D.; Bachovchin, D. A.
10.1101/2021.09.20.461118 — immunology — Posted on 2021-09-20
1444 Influenza A (N1-N9) and Influenza B (B/Vic and B/Yam) Neuraminidase Pseudotypes as Tools for Pandemic Preparedness and Improved Influenza Vaccine design
da Costa, K. A. S.; Del Rosario, J. M. M.; Ferrari, M.; Vishwanath, S.; Asbach, B.; Kinsley, R.; Wagner, R.; Heeney, J. L.; Carnell, G. W.; Temperton, N. J.
10.1101/2021.09.19.460966 — immunology — Posted on 2021-09-20
1446 The mechanobiology of craniosynostosis in Crouzon syndrome
Moazen, M.; Hejazi, M.; Savery, D.; Jones, D.; Marghoub, A.; Alazmani, A.; Pauws, E.
10.1101/2021.08.31.458360 — biophysics — Posted on 2021-09-20
1449 Sir3 Heterochromatin Protein Promotes NHEJ by Direct Inhibition of Sae2
Bordelet, H.; Costa, R.; Brocas, C.; DEPAGNE, J.; Veaute, X.; BUSSO, D.; Batte, A.; Guerois, R.; Marcand, S.; Dubrana, K.
10.1101/2021.05.26.445723 — genetics — Posted on 2021-09-20
1450 Taxon-specific or universal? Using target capture to study the evolutionary history of rapid radiations
Yardeni, G.; Viruel, J.; Paris, M.; Hess, J.; Groot Crego, C.; de La Harpe, M.; Rivera, N.; Barfuss, M. H. J.; Till, W.; Guzman-Jacob, V.; Kroemer, T.; Lexer, C.; Paun, O.; Leroy, T.
10.1101/2021.05.20.444989 — evolutionary biology — Posted on 2021-09-20
1453 A homeostatic interferon-lambda response to bacterial microbiota stimulates preemptive antiviral defense within discrete pockets of intestinal epithelium
Van Winkle, J. A.; Peterson, S. T.; Kennedy, E. A.; Wheadon, M. J.; Ingle, H.; Desai, C.; Rodgers, R.; Constant, D. A.; Wright, A. P.; Li, L.; Artyomov, M.; Lee, S.; Baldridge, M. T.; Nice, T. J.
10.1101/2021.06.02.446828 — immunology — Posted on 2021-09-20
1456 Mechanical overstimulation causes acute injury and synapse loss followed by fast recovery in lateral-line neuromasts of larval zebrafish
Holmgren, M.; Ravicz, M. E.; Hancock, K. E.; Strelkova, O.; Kallogjeri, D.; Indzhykulian, A. A.; Warchol, M. E.; Sheets, L.
10.1101/2020.07.15.205492 — neuroscience — Posted on 2021-09-20
1458 Metformin Confers Cardiac and Renal Protection in Sudden Cardiac Arrest via AMPK Activation
Rutledge, C.; Lagranha, C.; Chiba, T.; Redding, K.; Stolz, D.; Sims-Lucas, S.; Dezfulian, C.; Elmer, J.; Kaufman, B. A.
10.1101/2021.08.24.457506 — physiology — Posted on 2021-09-20
1463 Robust, Universal Tree Balance Indices
Lemant, J.; Le Sueur, C.; Manojlovic, V.; Noble, R. J.
10.1101/2021.08.25.457695 — evolutionary biology — Posted on 2021-09-20
1465 A functional corona around extracellular vesicles enhancesangiogenesis during skin regeneration and signals in immune cells
Wolf, m.; Poupardin, R.; Patricia, E.-P.; Andre, C.; Bloechl, C.; Obermayer, A.; Fausto, G. G.; Vari, B.; Eminger, E.; Binder, H. M.; Raninger, A. M.; Sarah, H.; Brachtl, G.; Spittler, A.; Heuser, T.; Racheli, O.; Huber, C. G.; Schallmoser, K.; Zami, A.; Volk, H. D.; Strunk, D.
10.1101/808808 — cell biology — Posted on 2021-09-20
1466 The essential transcriptional regulator HDP1 drives expansion of the inner membrane complex during early sexual differentiation of malaria parasites.
Campelo Morillo, R.; Tong, X.; Xie, W.; Abel, S.; Orchard, L. M.; Daher, W.; Patel, D.; Noble, W. S.; Le Roch, K. G.; Kafsack, B. F. C.
10.1101/2020.10.26.352583 — microbiology — Posted on 2021-09-20
1472 Characterizing the human methylome across the life course: findings from eight UK-based studies
Walton, E.; Marioni, R.; Elliott, H. R.; Cox, S. R.; Deary, I. R.; Hughes, A. D.; Tillin, T.; Kumari, M.; Woofenden, T.; Castillo-Fernandez, J. E.; Bell, J. T.; Goodman, A.; Ploubidis, G.; Tilling, K.; Suderman, M.; Gaunt, T. R.; Dunn, E. C.; Smith, A.; Relton, C.
10.1101/2021.09.18.460916 — genetics — Posted on 2021-09-20
1474 Global and regional ecological boundaries drive abrupt changes in avian frugivory interactions
Martins, L. P.; Stouffer, D. B.; Blendinger, P. G.; Bohning-Gaese, K.; Buitron-Jurado, G.; Correia, M.; Costa, J. M.; Dehling, D. M.; Donatti, C. I.; Emer, C.; Galetti, M.; Heleno, R.; Jordano, P.; Menezes, I.; Morante-Filho, J. C.; Munoz, M. C.; Neuschulz, E. L.; Pizo, M. A.; Quitian, M.; Ruggera, R. A.; Saavedra, F.; Santillan, V.; Schleuning, M.; Pascoal da Silva, L.; da Silva, F. R.; Timoteo, S.; Traveset, A.; Vollstadt, M. G. R.; Tylianakis, J. M.
10.1101/2021.09.18.460873 — ecology — Posted on 2021-09-20
1475 Analysis of the upper respiratory tract microbiota in mild and severe COVID-19 patients
Babenko, V. V.; Bakhtyev, R. R.; Baklaushev, V. P.; Balykova, L. A.; Bashkirov, P. V.; Bespyatykh, J. A.; Blagonravova, A. S.; Boldyreva, D. I.; Fedorov, D. E.; Gafurov, I. R.; Gaifullina, R. F.; Galeeva, J. S.; Galova, E. A.; Gospodaryk, A. V.; Ilina, E. N.; Ivanov, K. P.; Kharlampieva, D. D.; Khromova, P. A.; Klimina, K. M.; Kolontarev, K. B.; Kolyshkina, N. A.; Koritsky, A. V.; Kuropatkin, V. A.; Lazarev, V. N.; Manolov, A. I.; Manuvera, V. A.; Matyushkina, D. S.; Morozov, M. D.; Moskaleva, E. V.; Musarova, V. A.; Ogarkov, O. B.; Orlova, E. A.; Pavlenko, A. V.; Petrova, A. G.; Pozhenko, N.
10.1101/2021.09.20.461025 — molecular biology — Posted on 2021-09-20
1480 Development of novel potent ligands for GPR85, an orphan G protein-coupled receptor expressed in the brain
Sakai, A.; Yasui, T.; Watanave, M.; Tatsumi, R.; Yamamoto, Y.; Takano, W.; Tani, Y.; Okamura, I.; Hirai, H.; Takeda, S.; Takeda, S.
10.1101/2021.09.18.460934 — pharmacology and toxicology — Posted on 2021-09-20
1481 ESC - a comprehensive resource for SARS-CoV-2 immune escape variants
Rophina, M.; Pandhare, K.; Shamnath, A.; Imran, M.; Jolly, B.; Scaria, V.
10.1101/2021.02.18.431922 — bioinformatics — Posted on 2021-09-20
1482 iCOMIC: a graphical interface-driven bioinformatics pipeline for analyzing cancer omics data
Anilkumar Sithara, A.; Maripuri, D. P.; Moorthy, K.; Amirtha Ganesh, S. S.; Philip, P.; Banerjee, S.; Sudhakar, M.; Raman, K.
10.1101/2021.09.18.460896 — bioinformatics — Posted on 2021-09-20
1489 Full bandwidth electrophysiology of seizures and epileptiform activity enabled by flexible graphene micro-transistor depth neural probes
Bonaccini Calia, A.; Masvidal Codina, E.; Smith, T. M.; Schafer, N.; Rathore, D.; Rodriguez-Lucas, E.; Illa, X.; De la Cruz, J. M.; Del Corro, E.; Prats-Alfonso, E.; Viana, D.; Bousquet, J.; Hebert, C.; Martinez-Aguilar, J.; Sperling, J. R.; Drummond, M.; Halder, A.; Dodd, A.; Barr, K.; Savage, S.; Fornell, J.; Sort, J.; Guger, C.; Villa, R.; Kostarelos, K.; Wykes, R.; Guimera-Brunet, A.; Garrido, J. A.
10.1101/2021.09.17.460765 — neuroscience — Posted on 2021-09-20
1490 Reactivating Hippocampal-Mediated Memories to Disrupt the Reconsolidation of Fear
Grella, S. L.; Fortin, A. H.; Bladon, J. H.; Reynolds, L. F.; Ruesch, E.; Gross, A.; Shpokayte, M.; Cincotta, C.; Zaki, Y.; Ramirez, S.
10.1101/2021.09.16.460695 — neuroscience — Posted on 2021-09-20
1502 Optineurin links Hace1-dependent Rac ubiquitylation to integrin-mediated mechanotransduction to control bacterial invasion and cell division
Petracchini, S.; Hamaoui, D.; Doye, A.; Asnacios, A.; Fage, F.; Vitiello, E.; Balland, m.; Janel, S.; Lafont, F.; Gupta, M.; Ladoux, B.; Gilleron, J.; Maia, T. M.; Impens, F.; Gagnoux, L.; Daugaard, M.; Sorensen, P.; Lemichez, E.; Mettouchi, A.
10.1101/2021.09.19.460967 — cell biology — Posted on 2021-09-20
1503 Core cysteine residues in the PAN domain are critical for HGF/c-MET signaling
Pal, D.; De, K.; Shanks, C. M.; Feng, K.; Yates, T. B.; Morrell-Falvey, J.; Davidson, R. B.; Parks, J. M.; Muchero, W.
10.1101/2021.09.20.460979 — cell biology — Posted on 2021-09-20
1505 BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2
Samelson, A. J.; Tran, Q. D.; Robinot, R.; Carrau, L.; Rezelj, V. V.; Mac Kain, A.; Chen, M.; Ramadoss, G. N.; Guo, X.; Lim, S. A.; Lui, I.; Nunez, J.; Rockwood, S. J.; Wang, J.; Liu, N.; Carlson-Stevermer, J.; Oki, J.; Maures, T.; Holden, K.; Weissman, J. S.; Wells, J. A.; Conklin, B.; TenOever, B. R.; Chakrabarti, L. A.; Vignuzzi, M.; Tian, R.; Kampmann, M.
10.1101/2021.01.19.427194 — cell biology — Posted on 2021-09-20
1507 Experience-dependent changes in hippocampal spatial activity and hippocampal circuit function are disrupted in a rat model of Fragile X Syndrome
Asiminas, A.; Booker, S. A.; Dando, O. R.; Kozic, Z.; Arkell, D.; Inkpen, F. H.; Sumera, A.; Akyel, I.; Kind, P. C.; Wood, E. R.
10.1101/2021.09.17.460768 — neuroscience — Posted on 2021-09-20
1510 Circumscribing laser cuts attenuate seizure propagation in a mouse model of focal epilepsy
Lieberman, S.; Rivera, D. A.; Morton, R.; Hingorani, A.; Southard, T. L.; Johnson, L.; Reukauf, J.; Radwanski, R. E.; Zhao, M.; Nishimura, N.; Bracko, O.; Schwartz, T. H.; Schaffer, C. B.
10.1101/2021.09.17.460788 — neuroscience — Posted on 2021-09-20
1514 Volumetric ultrasound localization microscopy of the whole brain microvasculature
Heiles, B.; Chavignon, A.; Bergel, A.; Hingot, V.; Serroune, H.; Maresca, D.; Pezet, S.; Pernot, M.; Tanter, M.; Couture, O.
10.1101/2021.09.17.460797 — bioengineering — Posted on 2021-09-20
1515 OGT controls mammalian cell viability by regulating the proteasome/mTOR/ mitochondrial axis
Li, X.; Yue, X.; Sepulveda, H.; Burt, R. A.; Scott, D. A.; Carr, S. A.; Myers, S. A.; Rao, A.
10.1101/2021.09.19.461012 — cell biology — Posted on 2021-09-20
1517 Neuromuscular connectomes across development reveal synaptic ordering rules
Meirovitch, Y.; Kang, K.; Draft, R. W.; Pavarino, E. C.; Henao Echeverri, M. F.; Yang, F.; Turney, S. G.; Berger, D. R.; Peleg, A.; Schaleck, R. L.; Lu, J.; Tapia, J.-C.; Lichtman, J. W.
10.1101/2021.09.20.460480 — neuroscience — Posted on 2021-09-20
1518 Cerebellar stimulations prevent Levodopa-induced dyskinesia in mice and normalize brain activity
Coutant, B.; Frontera, J. L.; Perrin, E.; Combes, A.; Tarpin, T.; Menardy, F.; Mailhes-Hamon, C.; Perez, S.; Degos, B.; Venance, L.; Lena, C.; Popa, D.
10.1101/2021.09.17.460625 — neuroscience — Posted on 2021-09-20
1519 Hybrid EEG-EMG system to detect steering actions in car driving settings
Vecchiato, G.; Del Vecchio, M.; Ambeck-Madsen, J.; Ascari, L.; Avanzini, P.
10.1101/2021.09.16.460615 — neuroscience — Posted on 2021-09-20
1523 The aging lung mucosa: A proteomics study
Garcia-Vilanova, A.; Olmo-Fontanez, A. M.; Moliva, J. I.; Allue Guardia, A.; Singh, H.; Merrit, R. E.; Caceres, D. M.; Peters, J.; Wang, Y.; Schlesinger, L. S.; Turner, J.; Weintraub, S. T.; Torrelles, J. B.
10.1101/2021.09.14.460375 — systems biology — Posted on 2021-09-20
1524 Development of a novel, pan-variant aerosol intervention for COVID-19
Shoemaker, R. H.; Panettieri, R. A.; Libutti, S. K.; Hochster, H. S.; Watts, N. R.; Wingfield, P. T.; Starkl, P. M.; Pimenov, L.; Gawish, R.; Hladik, A.; Knapp, S.; Boring, D.; White, J. M.; Lawrence, Q.; Boone, J.; Marshall, J. D.; Matthews, R. L.; Cholewa, B. D.; Richig, J. W.; Chen, B. T.; McCormick, D. L.; Gugensberger, R.; Holler, S.; Penninger, J. M.; Wirnsberger, G.
10.1101/2021.09.14.459961 — pharmacology and toxicology — Posted on 2021-09-20
1525 Identification and Functional Annotation of Long Intergenic Non-coding RNAs in the Brassicaceae
Palos, K. R.; Nelson Dittrich, A. C.; Yu, L.; Brock, J. R.; Wu, L.; Sokolowska, E.; Skirycz, A.; Hsu, P. Y.; Lyons, E.; Beilstein, M.; Nelson, A. D. L.
10.1101/2021.09.17.460835 — genomics — Posted on 2021-09-20
1526 Host- and age-dependent transcriptional changes in Mycobacterium tuberculosis cell envelope biosynthesis genes after exposure to human alveolar lining fluid
Allue-Guardia, A.; Garcia-Vilanova, A.; Olmo-Fontanez, A. M.; Peters, J.; Maselli, D. J.; Wang, Y.; Turner, J.; Schlesinger, L. S.; Torrelles, J. B.
10.1101/2021.09.08.459334 — molecular biology — Posted on 2021-09-20
1527 Nanoscale organization of the endogenous ASC speck
Glueck, I. M.; Mathias, G. P.; Strauss, S.; Ebert, T. S.; Stafford, C.; Agam, G.; Manley, S.; Hornung, V.; Jungmann, R.; Sieben, C.; Lamb, D. C.
10.1101/2021.09.17.460822 — immunology — Posted on 2021-09-20
1529 TAAC - TMS Adaptable Auditory Control: a universal tool to mask TMS click
Russo, S.; Sarasso, S.; Puglisi, G. E.; Dal Palu, D.; Pigorini, A.; Casarotto, S.; D'Ambrosio, S.; Astolfi, A.; Massimini, M.; Rosanova, M.; Fecchio, M.
10.1101/2021.09.08.459439 — neuroscience — Posted on 2021-09-20
1530 Physical and functional interactome atlas of human receptor tyrosine kinases
Salokas, K.; Öhman, T.; Liu, X.; Chowdhury, I.; Gawriyski, L.; keskitalo, s.; Varjosalo, M.
10.1101/2021.09.17.460748 — systems biology — Posted on 2021-09-20
1531 Single-cell profiling reveals periventricular CD56bright NK cell accumulation in multiple sclerosis
Rodriguez-Lorenzo, S.; van Olst, L.; Rodriguez-Mogeda, C.; Kamermans, A.; van der Pol, S. M. A.; Rodriguez, E.; Kooij, G.; de Vries, H. E.
10.1101/2021.09.17.460741 — immunology — Posted on 2021-09-20
1532 Combining genotypes and T cell receptor distributions to infer genetic loci determining V(D)J recombination probabilities
Russell, M. L.; Souquette, A.; Levine, D. M.; Allen, E. K.; Kuan, G.; Simon, N.; Balmaseda, A.; Gordon, A.; Thomas, P.; Matsen, F. A.; Bradley, P. G.
10.1101/2021.09.17.460747 — immunology — Posted on 2021-09-20
1533 Perception affects the brain's metabolic response to sensory stimulation
DiNuzzo, M.; Mangia, S.; Moraschi, M.; Mascali, D.; Hagberg, G. E.; Giove, F.
10.1101/2021.09.17.460759 — neuroscience — Posted on 2021-09-20
1534 Energy status-promoted growth and development of Arabidopsis require copper deficiency response transcriptional regulator SPL7
Schulten, A.; Pietzenuk, B.; Quintana, J.; Krause, M.; Feil, R.; Romera-Branchat, M.; Wahl, V.; Severing, E.; Coupland, G.; Kraemer, U.
10.1101/2021.09.17.460807 — plant biology — Posted on 2021-09-20
1535 Using AlphaFold to predict the impact of single mutations on protein stability and function
Pak, M. A.; Markhieva, K. A.; Novikova, M. S.; Petrov, D. S.; Vorobyev, I. S.; Maksimova, E. S.; Kondrashov, F. A.; Ivankov, D. N.
10.1101/2021.09.19.460937 — bioinformatics — Posted on 2021-09-20
1536 Evolutionary history of an Alpine archaeognath(Machilis pallida) - insights from different variant types
Haider, M.; Schilling, M. P.; Moest, M. H.; Steiner, F. M.; Schlick-Steiner, B. C.; Arthofer, W.
10.1101/2021.09.17.460766 — evolutionary biology — Posted on 2021-09-20
1539 Mapping Epigenetic Divergence in the Massive Radiation of Lake Malawi Cichlid Fishes
Vernaz, G.; Malinsky, M.; Svardal, H.; Du, M.; Tyers, A. M.; Santos, M. E.; Durbin, R.; Genner, M. J.; Turner, G. F.; Miska, E. A.
10.1101/2020.11.24.383034 — genomics — Posted on 2021-09-20
1541 Detection and functional resolution of soluble multimeric immune complexes by a comprehensive FcγR reporter cell panel
Chen, H.; Maul-Pavicic, A.; Holzer, M.; Huber, M.; Salzer, U.; Chevalier, N.; Voll, R. E.; Hengel, H.; Kolb, P.
10.1101/2020.11.11.378232 — immunology — Posted on 2021-09-20
1542 Characterization of striatal dopamine projections across striatal subregions in behavioral flexibility
van der Merwe, R. K.; Nadel, J. A.; Copes-Finke, D.; Pawelko, S.; Scott, J.; Fox, M.; Morehouse, C.; Ghanem, M.; McLaughlin, R.; Maddox, C.; Malaki, G.; Turocy, A.; Jin, X.; Howard, C. D.
10.1101/2021.09.18.460922 — neuroscience — Posted on 2021-09-20
1544 Controllability reveals defining features of information seeking
Rouault, M.; Weiss, A.; Lee, J. K.; Drugowitsch, J.; Chambon, V.; Wyart, V.
10.1101/2021.01.04.425114 — neuroscience — Posted on 2021-09-20
1545 A thermodynamic model for interpreting tryptophan excitation-energy-dependent fluorescence spectra provides insight into protein conformational sampling and stability
Kwok, A.; Camacho, I.; Winter, S.; Knight, M.; Meade, R.; van der Kamp, M.; Turner, A.; O'Hara, J.; Mason, J.; Jones, A. R.; Arcus, V.; Pudney, C. R.
10.1101/2021.09.09.459605 — biophysics — Posted on 2021-09-20
1546 Bringing TrackMate into the era of machine-learning and deep-learning.
Ershov, D.; Phan, M.-S.; Pylvänäinen, J. W.; Rigaud, S. U.; Le Blanc, L.; Charles-Orszag, A.; Conway, J. R. W.; Laine, R. F.; Roy, N. H.; Bonazzi, D.; Dumenil, G.; Jacquemet, G.; Tinevez, J.-Y.
10.1101/2021.09.03.458852 — bioinformatics — Posted on 2021-09-20
1552 Benchmarking statistical methods for analyzing parent-child dyads in genetic association studies
Ray, D.; Vergara, C. I.; Taub, M. I.; Wojcik, G. L.; Ladd-Acosta, C.; Beaty, T. H.; Duggal, P.
10.1101/2021.09.16.460702 — genetics — Posted on 2021-09-20
1553 Visual gene expression reveals a cone to rod developmental progression in deep-sea fishes
Lupse, N.; Cortesi, F.; Freese, M.; Marohn, L.; Pohlmann, J.-D.; Wysujack, K.; Hanel, R.; Musilova, Z.
10.1101/2020.05.25.114991 — evolutionary biology — Posted on 2021-09-20
1555 An early signaling GARP transcription factor regulates the entry point for differentiation in Giardia
Shih, H.-W.; Alas, G. C. M.; Rydell, D. S.; Zhang, B.; Hamilton, G. A.; Kerr, B.; Paredez, A. R.
10.1101/2021.05.27.446072 — developmental biology — Posted on 2021-09-20
1556 Donor Macrophages Modulate Rejection after Heart Transplantation
Kopecky, B.; Dun, H.; Amrute, J.; Lin, C.-Y.; Bredemeyer, A.; Terada, Y.; Bayguinov, P.; Koenig, A.; Frye, C.; Fitzpatrick, J.; Kreisel, D.; Lavine, K.
10.1101/2021.09.17.459296 — immunology — Posted on 2021-09-20
1557 Non-lesional and Lesional Lupus Skin Share Inflammatory Phenotypes that Drive Activation of CD16+ Dendritic Cells
Billi, A. C.; Ma, F.; Plazyo, O.; Gharaee-Kermani, M.; Wasikowski, R.; Hile, G. A.; Xing, X.; Yee, C. M.; Rizvi, S. M.; Maz, M. P.; Wen, F.; Tsoi, L. C.; Pellegrini, M.; Modlin, R. L.; Gudjonsson, J. E.; Kahlenberg, J. M.
10.1101/2021.09.17.460124 — immunology — Posted on 2021-09-20
1559 Antigen identification and high-throughput interaction mapping by reprogramming viral entry
Dobson, C. S.; Reich, A. N.; Gaglione, S.; Smith, B. E.; Kim, E. J.; Dong, J.; Ronsard, L.; Okonkwo, V.; Lingwood, D.; Dougan, M.; Dougan, S. K.; Birnbaum, M. E.
10.1101/2021.09.18.460796 — immunology — Posted on 2021-09-20
1560 Chromomycin A5 induces bonafide immunogenic cell death in metastatic melanoma
Florencio, K. G. D.; Edson, E. A.; Pinto, F. d. C. L.; Pessoa, O. D. L.; Machado-Neto, J. A.; Wilke, D. V.
10.1101/2021.09.18.460876 — immunology — Posted on 2021-09-20
1561 Altered interactions between circulating and tissue-resident CD8 T cells with the colonic mucosa define colitis associated with immune checkpoint inhibitors
Thomas, M.; Slowikowski, K.; Manakongtreecheep, K.; Sen, P.; Tantivit, J.; Nasrallah, M.; Smith, N.; Ramesh, S.; Zubiri, L.; Tirard, A.; Arnold, B.; Nieman, L.; Chen, J.; Eisenhaure, T.; Pelka, K.; Xu, K.; Jorgji, V.; Pinto, C.; Sharova, T.; Glasser, R.; Chan, E. P.; Sullivan, R.; Khalili, H.; Juric, D.; Boland, G.; Dougan, M.; Hacohen, N.; Reynolds, K.; Li, B.; Villani, A.-C.
10.1101/2021.09.17.460868 — immunology — Posted on 2021-09-20
1562 Short-term assessment of subfoveal injection of AAV2-hCHM gene augmentation in choroideremia using adaptive optics ophthalmoscopy
Morgan, J. I. W.; Jiang, Y. Y.; Vergilio, G. K.; Serrano, L. W.; Pearson, D. J.; Bennett, J.; Maguire, A. M.; Aleman, T. S.
10.1101/2021.09.17.459817 — neuroscience — Posted on 2021-09-20
1566 Novel biochemical, structural and systems insights into inflammatory signaling revealed by contextual interaction proteomics
Ciuffa, R.; Uliana, F.; Mehnert, M.; Marulli, C.; Satanowski, A.; Ramirez, P. N. R.; Meier, P.; Ori, A.; Gstaiger, M.; Aebersold, R.
10.1101/2021.09.18.460902 — systems biology — Posted on 2021-09-20
1567 A ppGpp-mediated brake on photosynthesis is required for acclimation to nitrogen limitation in Arabidopsis.
Romand, S.; Abdelkefi, H.; Lecampion, C.; Belaroussi, M.; Dusenne, M.; Ksas, B.; Citerne, S.; Caius, J.; D'Alessandro, S.; Fakhfakh, H.; Caffarri, S.; Havaux, M.; Field, B.
10.1101/2021.09.18.460674 — plant biology — Posted on 2021-09-20
1573 SL-Cloud: A Computational Resource to Support Synthetic Lethal Interaction Discovery
Tercan, B.; Qin, G.; Kim, T.; Aguilar, B.; Kemp, C. J.; Chambwe, N.; Shmulevich, I.
10.1101/2021.09.18.459450 — bioinformatics — Posted on 2021-09-19
1575 Taxonomy Analysis in Bacteria Kingdom based onProtein Domain: A Comparison Study
Wang, B.; Zhou, J.; Jin, Y.; Hu, M.; Zhao, Y.; Wang, X.; Yang, H.; Gong, X.; Zhang, F.; Zhang, Z.; Kang, F.; Liang, L.; Yue, J.; Ren, H.
10.1101/2021.09.17.460715 — bioinformatics — Posted on 2021-09-20
1577 Group size planning of breedings of gene-modified animals
Milchevskaya, V.; Bugnon, P.; ten Buren, E. B. J.; Brand, F.; Tresch, A.; Buch, T.
10.1101/2021.09.17.460764 — bioinformatics — Posted on 2021-09-20
1578 SMAP: A pipeline for sample matching in proteogenomics
Li, L.; Niu, M.; Erickson, A.; Luo, J.; Rowbotham, K.; Huang, H.; Li, Y.; Jiang, Y.; Liu, C.; Peng, J.; Wang, X.
10.1101/2021.09.17.460682 — bioinformatics — Posted on 2021-09-20
1580 SEQUENCE SLIDER: integration of structural and genetic data to characterize isoforms from natural source
Borges, R. J.; Salvador, G. H. M.; Pimenta, D.; dos Santos, L. D.; Fontes, M. R. d. M.; Uson, I.
10.1101/2021.09.16.460517 — bioinformatics — Posted on 2021-09-20
1581 Blood flow modeling reveals improved collateral artery performance during mammalian heart regeneration
Anbazhakan, S.; Rios Coronado, P. E.; Sy-Quia, A. N. L.; Seow, A.; Hands, A. M.; Cook, C. K.; Zhao, M.; Dong, M. L.; Pfaller, M.; Bernstein, D.; Raftrey, B. C.; Nieman, K.; Pasca, A. M.; Marsden, A. L.; Red-Horse, K.
10.1101/2021.09.17.460699 — bioengineering — Posted on 2021-09-19
1583 Directing multicellular organization by varying the aspect ratio of soft hydrogel microwells
Pahapale, G. J.; Tao, J.; Nikolic, M.; Gao, S.; Scarcelli, G.; Sun, S.; Romer, L. H.; Gracias, D. H.
10.1101/2021.09.17.460849 — bioengineering — Posted on 2021-09-20
1588 The evolutionary pathways for local adaptation in mountain hares
Giska, I.; Pimenta, J.; Farelo, L.; Boursot, P.; Hackländer, K.; Jenny, H.; Reid, N.; Montgomery, W. I.; Prodöhl, P.; Alves, P. C.; Melo-Ferreira, J.
10.1101/2021.09.16.460230 — evolutionary biology — Posted on 2021-09-19
1595 Progenitor cell integration into a barrier epithelium during adult organ turnover
Moreno-Roman, P.; Su, Y.-H.; Galenza, A.; Acosta, L.; Debec, A.; Guichet, A.; Knapp, J.-M.; Kizilyaprak, C.; Humbel, B. M.; Kolotuev, I.; O'Brien, L. E.
10.1101/2021.09.19.457819 — developmental biology — Posted on 2021-09-19
1599 Evolution of antigen-specific follicular helper T cell transcriptional programs across effector function and through to memory
Robinson, A. M.; Higgins, B. W.; Shuparski, A. G.; Miller, K. B.; McHeyzer-Williams, L. J.; McHeyzer-Williams, M. G.
10.1101/2021.09.17.460841 — immunology — Posted on 2021-09-19
1601 Behavioral prioritization enhances working memory precision and neural population gain
Yoo, A. H.; Bolanos, A.; Hallenbeck, G. E.; Rahmati, M.; Sprague, T. C.; Curtis, C. E.
10.1101/2021.09.16.460676 — neuroscience — Posted on 2021-09-19
1602 Serotonin regulates hepcidin expression via a gut-liver axis
Coman, T.; Falabregue, M.; Rossignol, J.; Bonneau, P.; Djebar, M.; Bigorgne, A.; Mathieu, J. R.; Foretz, M.; Puy, H.; Peoc'h, K.; Legeart, D.; Cohen-Solal, A.; Launay, J.-M.; Maroteaux, L.; Peyssonnaux, C.; Hermine, O.; Cote, F.
10.1101/2021.09.16.460464 — physiology — Posted on 2021-09-19
1604 Ribosomal RNA 2'-O-methylations regulate translation by impacting ribosome dynamics
Khoshnevis, S.; Dreggors-Walker, R. E.; Marchand, V.; Motorin, Y.; Ghalei, H.
10.1101/2021.09.18.460910 — biochemistry — Posted on 2021-09-19
1608 Distinct C4 Sub-Types and C3 Bundle Sheath Isolation In The Paniceae Grasses
Washburn, J. D.; Strable, J.; Dickinson, P.; Kothapalli, S. S.; Brose, J. M.; Covshoff, S.; Conant, G. C.; Hibberd, J. M.; Pires, J. C.
10.1101/162644 — plant biology — Posted on 2021-09-19
1609 A Taphrina strain infecting the model plant Arabidopsis thaliana.
Christita, M.; Auzane, A.; Wang, K.; Sipilä, T.; Auvinen, P.; Paulin, L.; Salojärvi, J.; Overmyer, K.
10.1101/2021.09.16.460675 — plant biology — Posted on 2021-09-19
1610 Colony-like Protocell Superstructures
Spustova, K.; Katke, C.; Pedrueza Villalmanzo, E.; Ryskulov, R.; Kaplan, C. N.; Gozen, I.
10.1101/2021.09.16.460583 — biophysics — Posted on 2021-09-19
1611 Structural and biochemical analyses of selectivity determinants in chimeric Streptococcus Class A sortase enzymes
Gao, M.; Johnson, D. A.; Piper, I. M.; Kodama, H. M.; Svendsen, J. E.; Tahti, E.; Vogel, B.; Antos, J.; Amacher, J.
10.1101/2021.09.19.461001 — biochemistry — Posted on 2021-09-19
1612 Necroptosis contributes to chronic inflammation and fibrosis in aging liver
Mohammed, S.; Thadathil, N.; Selvarani, R.; Nicklas, E. H.; Wang, D.; Miller, B. F.; Richardson, A.; Deepa, S. S.
10.1101/2021.09.19.460953 — biochemistry — Posted on 2021-09-19
1614 N-myc Downstream Regulated Gene 1 (NDRG1) functions as a molecular switch for cellular adaptation to hypoxia
Park, J. S.; Gabel, A. M.; Kang, L.; Canales, B.; Kassir, P.; Osei-Ntansah, A.; Tran, N. D.; Viswanathan, S.; Lee, Y.-S.; Brewster, R.
10.1101/2021.09.10.459675 — developmental biology — Posted on 2021-09-19
1615 Shedding light on biosilica morphogenesis by comparative analysis of the silica-associated proteomes from three diatom species
Skeffington, A.; Gentzel, M.; Ohara, A.; Milentyev, A.; Heintze, C.; Böttcher, L.; Görlich, S.; Shevchenko, A.; Poulsen, N.; Kröger, N.
10.1101/2021.09.18.460806 — molecular biology — Posted on 2021-09-19
1616 Targeted biallelic integration of an inducible Caspase 9 suicide gene for safer iPSC-based cellular therapies
Wunderlich, S.; Haase, A.; Merkert, S.; Jahn, K.; Deest, M.; Glage, S.; Korte, W.; Martens, A.; Kirschning, A.; Zeug, A.; Ponimaskin, E.; Goehring, G.; Ackermann, M.; Lachmann, N.; Moritz, T.; Zweigerdt, R.; Martin, U.
10.1101/2021.09.19.460940 — molecular biology — Posted on 2021-09-19
1617 A specific eIF4A paralog facilitates LARP1-mediated translation repression during mTORC1 inhibition
Shichino, Y.; Mito, M.; Kashiwagi, K.; Takahashi, M.; Ito, T.; Ingolia, N. T.; Iwasaki, S.
10.1101/2021.09.18.460932 — molecular biology — Posted on 2021-09-19
1618 The master energy homeostasis regulator PGC-1alpha couples transcriptional co-activation and mRNA nuclear export
Mihaylov, S. R.; Castelli, L. M.; Lin, Y.-H.; Gul, A.; Soni, N.; Hastings, C.; Flynn, H. R.; Dickman, M. J.; Snijders, A. P.; Bandmann, O.; Mortiboys, H.; Ultanir, S. K.; Hautbergue, G. M.
10.1101/2021.09.19.460961 — molecular biology — Posted on 2021-09-19
1619 Identification of Serum Bridging Molecules that Mediate Human Endothelial Cell Invasion by Candida species
Phan, Q. T.; Solis, N. V.; Lin, J.; Swidergall, M.; Singh, S.; Liu, H.; Sheppard, D.; Ibrahim, A.; Mitchell, A. P.; Filler, S. G.
10.1101/2021.09.18.460925 — microbiology — Posted on 2021-09-19
1623 BRAFV600E induces reversible mitotic arrest in human melanocytes via microRNA-mediated suppression of AURKB.
McNeal, A. S.; Belote, R. L.; Zeng, H.; Urquijo, M.; Barker, K.; Torres, R.; Curtin, M.; Shain, A. H.; Andtbacka, R. H.; Holmen, S. L.; Lum, D. H.; McCalmont, T.; VanBrocklin, M. W.; Grossman, D.; Wei, M. L.; Lang, U. E.; Judson-Torres, R. L.
10.1101/2020.05.21.109397 — cancer biology — Posted on 2021-09-19
1624 Elys deficiency constrains Kras-driven tumour burden by amplifying oncogenic stress
Morgan, K. J.; Doggett, K.; Geng, F.-S.; Whitehead, L.; Smith, K. A.; Hogan, B. M.; Simons, C.; Baillie, G. J.; Molania, R.; Papenfuss, A. T.; Hall, T. E.; Ober, E. A.; Stainier, D. Y. R.; Gong, Z.; Heath, J. K.
10.1101/2021.08.25.457580 — cancer biology — Posted on 2021-09-19
1626 Synthesizing VERDICT maps from standard DWI data using GANs
Chiou, E.; Valindria, V.; Giganti, F.; Punwani, S.; Kokkinos, I.; Panagiotaki, E.
10.1101/2021.02.16.431521 — bioengineering — Posted on 2021-09-19
1627 DNA dynamics dictates p53 functional outcome
Safieh, J.; Chazan, A.; Vyas, P.; Saleem, H.; Danin-Poleg, Y.; Ron, D.; Haran, T. E.
10.1101/2021.09.18.460898 — biochemistry — Posted on 2021-09-19
1628 A robust approach to estimate relative phytoplankton cell abundance from metagenomes
Pierella Karlusich, J. J.; Pelletier, E.; Zinger, L.; Lombard, F.; Zingone, A.; Colin, S.; Gasol, J. M.; Dorrell, R.; Scalco, E.; Acinas, S. G.; Wincker, P.; de Vargas, C.; Bowler, C.
10.1101/2021.05.28.446125 — ecology — Posted on 2021-09-19
1630 Regulation of Myoepithelial Differentiation in 3-Dimensional Culture
Thiemann, R. F.; Varney, S.; Moskwa, N.; Lamar, J.; Larsen, M.; LaFlamme, S. E.
10.1101/2021.06.28.450182 — cell biology — Posted on 2021-09-19
1634 Lysosome-related organelles contain an expansion compartment that mediates delivery of zinc transporters to promote homeostasis
Mendoza, A. D.; Dietrich, N.; Tan, C.-H.; Herrera, D. E.; Kasiah, J.; Payne, Z.; Schneider, D. L.; Kornfeld, K.
10.1101/2021.09.18.460850 — cell biology — Posted on 2021-09-19
1635 Symmetry breaking of hPSCs in micropattern generates a polarized spinal cord-like organoid (pSCO) with dorsoventral organization
Seo, K.; Cho, S.; Lee, J.-H.; Kim, J. H.; Lee, B.; Jang, H.; Kim, Y.; Cho, H. M.; Lee, S.; Park, Y.; Kim, H. Y.; Lee, T.; Park, W.-Y.; Kim, Y. J.; Yang, E.; Geum, D.; Kim, H.; Ryu, J. R.; Sun, W.
10.1101/2021.09.18.460734 — developmental biology — Posted on 2021-09-19
1636 Cochlear organoids reveal epigenetic and transcriptional programs of postnatal hair cell differentiation from supporting cells
Kalra, G.; Lenz, D.; Abdul-Aziz, D.; Hanna, C.; Herb, B.; Colantuoni, C.; Milon, B.; Saxena, M.; Shetty, A. C.; Hertzano, R. P.; Shivdasani, R.; Ament, S. A.; Edge, A. S.
10.1101/2021.09.19.460948 — developmental biology — Posted on 2021-09-19
1640 Whole-cell modeling in yeast predicts compartment-specific proteome constraints that drive metabolic strategies
Elsemman, I. E.; Rodriguez Prado, A.; Grigaitis, P.; Garcia Albornoz, M.; Harman, V.; Holman, S. W.; van Heerden, J.; Bruggeman, F. J.; Bisschops, M. M. M.; Sonnenschein, N.; Hubbard, S.; Beynon, R.; Daran-Lapujade, P.; Nielsen, J.; Teusink, B.
10.1101/2021.06.11.448029 — systems biology — Posted on 2021-09-19
1642 WDR60-mediated dynein-2 loading into cilia powers retrograde IFT and transition zone crossing
De-Castro, A. R. G.; Rodrigues, D. R. M.; De-Castro, M. J. G.; Vieira, N.; Vieira, C.; Carvalho, A. X.; Gassmann, R.; Abreu, C. M. C.; Dantas, T. J.
10.1101/2021.09.19.459328 — cell biology — Posted on 2021-09-19
1643 Reversing chemorefraction in colorectal cancer cells by controlling mucin secretion
Cantero-Recasens, G.; Alonso-Maranon, J.; Lobo-Jarne, T.; Garrido, M.; Iglesias, M.; Espinosa, L.; Malhotra, V.
10.1101/2021.09.17.460827 — cell biology — Posted on 2021-09-19
1644 When development is constantly but weakly perturbed - Canalization by microRNAs
Lu, G.-A.; Zhao, Y.; Chen, Q.; Lin, P.; Tang, T.; Tang, Z.; Liufu, Z.; Wu, C.-I.
10.1101/2021.09.04.458966 — molecular biology — Posted on 2021-09-19
1647 Oscillatory and aperiodic neural activity jointly predict language learning
Cross, Z. R.; Corcoran, A. W.; Schlesewsky, M.; Kohler, M. J.; Bornkessel-Schlesewsky, I.
10.1101/2020.03.10.984971 — neuroscience — Posted on 2021-09-19
1649 CUX2 mutations in temporal lobe epilepsy; increased kainate susceptibility and excitatory input to hippocampus in deficient mice
Suzuki, T.; Tatsukawa, T.; Sudo, G.; Delandre, C.; Pai, Y. J.; Miyamoto, H.; Raveau, M.; Shimohata, A.; Ohmori, I.; Hamano, S.-i.; Haginoya, K.; Uematsu, M.; Takahashi, Y.; Morimoto, M.; Fujimoto, S.; Osaka, H.; Oguni, H.; Osawa, M.; Ishii, A.; Hirose, S.; Kaneko, S.; Inoue, Y.; Moore, A. W.; Yamakawa, K.
10.1101/2021.09.17.460803 — neuroscience — Posted on 2021-09-18
1650 Massively parallel encapsulation of single cells with structured microparticles and secretion-based flow sorting
de Rutte, J.; Dimatteo, R.; Archang, M. M.; van Zee, M.; Koo, D.; Lee, S.; Sharrow, A. C.; Krohl, P. J.; Mellody, M. P.; Zhu, S.; Eichenbaum, J.; Kizerwetter, M.; Udani, S.; Ha, K.; Bertozzi, A. L.; Spangler, J. B.; Damoiseaux, R.; Di Carlo, D.
10.1101/2020.03.09.984245 — bioengineering — Posted on 2021-09-18
1651 A flexible electronic strain sensor for the real-time monitoring of tumor progression
Abramson, A.; Chan, C.; Khan, Y.; Mermin-Bunnell, A.; Matsuhisa, N.; Fong, R.; Shad, R.; Hiesinger, W.; Mallick, P.; Gambhir, S. S.; Bao, Z.
10.1101/2021.09.16.460551 — bioengineering — Posted on 2021-09-18
1652 Structural analysis and construction of thermostable antifungal chitinase
Kozome, D.; Uechi, K.; Taira, T.; fukada, h.; Kubota, T.; Ishikawa, K.
10.1101/2021.09.17.460877 — biochemistry — Posted on 2021-09-18
1654 Thymocyte regulatory variant alters transcription factor binding and protects from type 1 diabetes in infants
Sandholm, N.; Rubio Garcia, A.; Pekalski, M. L.; Inshaw, J. R.; Cutler, A. J.; Todd, J. A.
10.1101/2021.09.17.460789 — genetics — Posted on 2021-09-18
1656 Deconstructing Gastrulation at the Single Cell Level
Stern, T.; Streichan, S. J.; Shvartsman, S. Y.; Wieschaus, E. F.
10.1101/2021.09.16.460711 — developmental biology — Posted on 2021-09-18
1659 Nanoscale organization of the endogenous ASC speck
Glueck, I. M.; Mathias, G. P.; Strauss, S.; Ebert, T. S.; Stafford, C.; Agam, G.; Manley, S.; Hornung, V.; Jungmann, R.; Sieben, C.; Lamb, D. C.
10.1101/2021.09.17.460822 — immunology — Posted on 2021-09-18
1660 Genetically engineered microglia-like cells have therapeutic potential for neurodegenerative disease
Plasschaert, R. N.; DeAndrade, M. P.; Hull, F.; Nguyen, Q.; Peterson, T.; Yan, A.; Loperfido, M.; Baricordi, C.; Barbarossa, L.; Yoon, J. K.; Dogan, Y.; Unnisa, Z.; Schindler, J. W.; van Til, N. P.; Biasco, L.; Mason, C.
10.1101/2021.09.16.460703 — neuroscience — Posted on 2021-09-18
1662 Transmembrane Batten disease proteins interact with a shared network of vesicle sorting proteins to regulate synaptic composition and function.
Rechtzigel, M. J.; Meyerink, B. L.; Leppert, H.; Johnson, T. B.; Cain, J. T.; Ferrandino, G.; May, D. G.; Roux, K. J.; Brudvig, J. J.; Weimer, J. M.
10.1101/2021.09.16.460691 — neuroscience — Posted on 2021-09-18
1663 A CLN6-CRMP2-KLC4 complex regulates anterograde ER-derived vesicle trafficking in cortical neurites
Koh, S. Y.; Cain, J. T.; Magee, H.; White, K. A.; Rechtzigel, M.; Meyerink, B.; Leppert, H.; Timm, D. J.; Morgan, J. P.; Johnson, T. B.; Grove, B.; Khanna, R.; Hensley, K.; Brudvig, J.; Weimer, J. M.
10.1101/2021.09.16.460653 — neuroscience — Posted on 2021-09-18
1664 Mu-opioid receptor system modulates responses to vocal bonding and distress signals in humans
Sun, L.; Lukkarinen, L.; Karlsson, H.; Hirvonen, J.; Tiihonen, J.; Lauerma, H.; Scott, S.; Nummenmaa, L.
10.1101/2021.09.16.460660 — neuroscience — Posted on 2021-09-18
1665 Data Representation in the DARPA SD2 Program
Roehner, N.; Beal, J.; Bartley, B.; Markeloff, R.; Mitchell, T.; Nguyen, T.; Sumorok, D.; Walczak, N.; Myers, C.; Zundel, Z.; Scholz, J.; Hatch, B.; Weston, M.; Colonna-Romano, J.
10.1101/2021.09.17.460644 — synthetic biology — Posted on 2021-09-18
1666 Characterization of the Brassica napus flavonol synthase gene family reveals bifunctional flavonol synthases
Schilbert, H. M.; Schoene, M.; Baier, T.; Busche, M.; Viehoever, P.; Weisshaar, B.; Holtgraewe, D.
10.1101/2021.06.30.450533 — plant biology — Posted on 2021-09-18
1668 Sister chromatid exchanges induced by perturbed replication are formed independently of homologous recombination factors
Heijink, A. M.; Stok, C.; Porubsky, D.; Manolika, E. M.; Kok, Y. P.; Everts, M.; de Boer, H. R.; Audrey, A.; Wierenga, E.; Guryev, V.; Spierings, D. C. J.; Knipscheer, P.; Ray Chaudhuri, A.; Lansdorp, P. M.; van Vugt, M. A. T. M.
10.1101/2021.09.17.460736 — cancer biology — Posted on 2021-09-18
1670 In Silico Electrophysiology of Inner-Ear Mechanotransduction Channel TMC1 Models
Walujkar, S.; Lotthammer, J. M.; Nisler, C. R.; Sudar, J. C.; Ballesteros, A.; Sotomayor, M.
10.1101/2021.09.17.460860 — biophysics — Posted on 2021-09-18
1671 The effect of pre-analytical and physiological variables on cell-free DNA fragmentation.
van der Pol, Y.; Moldovan, N.; Verkuijlen, S.; Ramaker, J.; Boers, D.; Onstenk, W.; de Rooij, J.; Bahce, I.; Pegtel, D. M.; Mouliere, F.
10.1101/2021.09.17.460828 — genomics — Posted on 2021-09-18
1672 New Data and Collaborations at the Saccharomyces Genome Database: Updated reference genome, alleles, and the Alliance of Genome Resources
Engel, S. R.; Wong, E. D.; Nash, R. S.; Aleksander, S.; Alexander, M.; Douglass, E.; Karra, K.; Miyasato, S. R.; Simison, M.; Skrzypek, M. S.; Weng, S.; Cherry, J. M.
10.1101/2021.09.16.460706 — genetics — Posted on 2021-09-18
1675 MinION nanopore sequencing provides similar methylation estimates to Sanger bisulfite sequencing in the TRPA1 promoter region
Gombert, S.; Jahn, K.; Pathak, H.; Burkert, A.; Schmidt, G.; Wiehlmann, L.; Davenport, C.; Braendl, B.; Mueller, F. J.; Leffler, A.; Deest, M.; Frieling, H.
10.1101/2021.09.17.460763 — molecular biology — Posted on 2021-09-18
1677 Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment
Schwabkey, Z.; Wiesnoski, D.; Chang, C.-C.; Tsai, W.-B.; Pham, D.; Ahmed, S. S.; Hayase, T.; Ortega Turrubiates, M. R.; El-Himri, R. K.; Sanchez, C. A.; Hayase, E.; Frenk Oquendo, A. C.; Miyama, T.; Halsey, T. M.; Heckel, B. E.; Brown, A. N.; Jin, Y.; Lorenzi, P. L.; Warmoes, M. O.; Tan, L.; Swennes, A.; Jensen, V. B.; Peterson, C. B.; Do, K.-A.; Zhang, L.; Shi, Y.; Wang, Y.; Galloway-Pena, J. R.; Okhuysen, P. C.; Daniel-MacDougall, C.; Shono, Y.; Burgos da Silva, M.; Peled, J.; van den Brink, M. R.; Ajami, N. J.; Wargo, J.; Rondon, G.; Srour, S. A.; Mehta, R. S.; Alousi, A. M.; Shpall, E. J.;
10.1101/2021.09.18.460647 — microbiology — Posted on 2021-09-18
1678 Adropin confers neuroprotection and promotes functional recovery from ischemic stroke
Yang, C.; Lavayen, B. P.; Liu, L.; Sanz, B. D.; DeMars, K. M.; Larochelle, J.; Pompilus, M.; Febo, M.; Sun, Y.-Y.; Kuo, Y.-M.; Mohamadzadeh, M.; Farr, S. A.; Kuan, C.-Y.; Butler, A. A.; Candelario-Jalil, E.
10.1101/2021.09.16.460662 — neuroscience — Posted on 2021-09-18
1680 Sex differences in cardio-pulmonary pathology of SARS-CoV2 infected and Trypanosoma cruzi co-infected mice
Dhanyalayam, D.; Lizardo, K.; Oswal, N.; Thangavel, H.; Dolgov, E.; Perlin, D. S.; Nagajyothi, J. F.
10.1101/2021.09.18.460895 — pathology — Posted on 2021-09-18
1684 Genetically diverse mouse models of SARS-CoV-2 infection model clinical variation and cytokine responses in COVID-19
Robertson, S.; Bedard, O.; McNally, K.; Lewis, M.; Clancy, C.; Shaia, C.; Broeckel, R.; Chiramel, A.; Sturdevant, G.; Forte, E.; Preuss, C.; Baker, C.; Sturdevant, D.; Martens, C.; Holland, S.; Rosenthal, N.; Best, S.
10.1101/2021.09.17.460664 — microbiology — Posted on 2021-09-18
1687 A p53-Phosphoinositide Signalosome Regulates Nuclear Akt Activation
Chen, M.; Choi, S.; Wen, T.; Chen, C.; Thapa, N.; Cryns, V. L.; Anderson, R. A.
10.1101/2021.09.17.460854 — cell biology — Posted on 2021-09-18
1688 Dual regulation of spine-specific and synapse-to-nucleus signaling by PKCδ during plasticity
Colgan, L. A.; Parra-Bueno, P.; Holman, H. L.; Calubag, M. F.; Misler, J. A.; Tu, X.; Yasuda, R.
10.1101/2021.09.17.460844 — neuroscience — Posted on 2021-09-18
1689 Nitrogen partitioning between branched-chain amino acids and urea cycle enzymes sustains renal cancer progression
Sciacovelli, M.; Dugourd, A.; Valcarcel Jimenez, L.; Yang, M.; Nikitopoulou, E.; Costa, A. S.; Tronci, L.; Caraffini, V.; Rodrigues, P.; Schmidt, C.; Ryan, D. G.; Young, T.; Zecchini, V.; Rossi, S. H.; Massie, C.; Lohoff, C.; Masid, M.; Hatzimanikatis, V.; Kuppe, C.; Von Kriegsheim, A.; Kramann, R.; Gnanapragasam, V.; Warren, A. Y.; Stewart, G. D.; Erez, A.; Vanharanta, S.; Saez-Rodriguez, J.; Frezza, C.
10.1101/2021.09.17.460635 — cancer biology — Posted on 2021-09-18
1693 Scale Invariance in fNIRS as a Measurement of Cognitive Load
Zhuang, C.; Meidenbauer, K. L.; Kardan, O.; Stier, A. J.; Choe, K. W.; Cardenas-Iniguez, C.; Huppert, T. J.; Berman, M. G.
10.1101/2021.08.31.458427 — neuroscience — Posted on 2021-09-18
1694 A B73 x Palomero Toluqueo mapping population reveals local adaptation in Mexican highland maize
Perez-Limon, S.; Li, M.; Cintora-Martinez, G. C.; Aguilar-Rangel, M. R.; Salazar-Vidal, M. N.; Gonzalez-Segovia, E.; Blöcher-Juarez, K. A.; Guerrero-Zavala, A.; Barrales-Gamez, B.; Carcano-Macias, J. L.; Costich, D. E.; Nieto-Sotelo, J.; Martinez-De la Vega, O.; Simpson, J.; Hufford, M.; Ross-Ibarra, J.; Flint-Garcia, S.; Diaz-Garcia, L.; Rellan-Alvarez, R.; Sawers, R. J.
10.1101/2021.09.15.460568 — plant biology — Posted on 2021-09-18
1695 Hotter chili peppers by hybridisation: heterosis and reciprocal effects
Naves, E. R.; Scossa, F.; Araujo, W. L.; Nunes-Nesi, A.; Fernie, A. R.; Zsögön, A.
10.1101/2021.09.16.460669 — plant biology — Posted on 2021-09-18
1696 3D virtual Histopathology of Cardiac Tissue from Covid-19 Patients based on Phase-Contrast X-ray Tomography
Reichardt, M.; Moller Jensen, P.; Andersen Dahl, V.; Bjorholm Dahl, A.; Ackermann, M.; Shah, H.; Länger, F.; Werlein, C.; Kuehnel, M. P.; Jonigk, D.; Salditt, T.
10.1101/2021.09.16.460594 — pathology — Posted on 2021-09-18
1697 Altered fibrin clot structure contributes to thrombosis risk in severe COVID-19
Wygrecka, M.; Birnhuber, A.; Seeliger, B.; Michalick, L.; Pak, O.; Schultz, A.-S.; Schramm, F.; Zacharias, M.; Gorkiewicz, G.; David, S.; Welte, T.; Schmidt, J. J.; Weissmann, N.; Schermuly, R. T.; Barreto, G.; Schäfer, L.; Markart, P.; Brack, M. C.; Hippenstiel, S.; Kurth, F.; Sander, L. E.; Witzenrath, M.; Kuebler, W. M.; Kwapiszewska, G.; Preissner, K. T.
10.1101/2021.09.17.460777 — biochemistry — Posted on 2021-09-18
1698 Global chromosome topology and the two-component systems in concerted manner regulate transcription in Streptomyces
Gongerowska-Jac, M.; Szafran, M. J.; Mikołajczyk, J.; Szymczak, J.; Bartynska, M.; Gierlikowska, A.; Biały, S.; Elliot, M. A.; Jakimowicz, D.
10.1101/2021.09.15.460574 — genomics — Posted on 2021-09-18
1699 Androglobin, a chimeric mammalian globin, is required for male fertility
Keppner, A.; Correia, M.; Santambrogio, S.; Koay, T. W.; Maric, D.; Osterhof, C.; Winter, D. V.; Clerc, A.; Stumpe, M.; Chalmel, F.; Dewilde, S.; Odermatt, A.; Kressler, D.; Hankeln, T.; Wenger, R. H.; Hoogewijs, D.
10.1101/2021.09.16.460596 — developmental biology — Posted on 2021-09-18
1701 Scaling between stomatal size and density in forest plants
Liu, C.; Muir, C. D.; Li, Y.; Xu, L.; Li, M.; Zhang, J.; de Boer, H. J.; Sack, L.; Han, X.; Yu, G.; He, N.
10.1101/2021.04.25.441252 — plant biology — Posted on 2021-09-18
1702 Uterus-specific transcriptional regulation underlies eggshell pigment production in Japanese quail
Ishishita, S.; Kitahara, S.; Takahashi, M.; Iwasaki, S.; Tatsumoto, S.; Hara, I.; Kaneko, Y.; Kinoshita, K.; Yamaguchi, K.; Harada, A.; Ohmori, Y.; Ohkawa, Y.; Go, Y.; Shigenobu, S.; Matsuda, Y.; Suzuki, T.
10.1101/2021.09.15.460419 — genetics — Posted on 2021-09-18
1703 Darwin's finches - an adaptive radiation constructed from ancestral genetic modules
Rubin, C.-J.; Enbody, E. D.; Dobreva, M. P.; Abzhanov, A.; Davis, B. W.; Lamichhaney, S.; Pettersson, M. E.; Sprehn, C. G.; Valle, C. A.; Vasco, K.; Wallerman, O.; Grant, B. R.; Grant, P.; Andersson, L.
10.1101/2021.09.17.460815 — evolutionary biology — Posted on 2021-09-18
1708 Two common and distinct forms of variation in human functional brain networks
Dworetsky, A.; Seitzman, B. A.; Adeyemo, B.; Smith, D. M.; Petersen, S. E.; Gratton, C.
10.1101/2021.09.17.460799 — neuroscience — Posted on 2021-09-18
1709 Cellular heterogeneity of human fallopian tubes in normal and hydrosalpinx disease states identified by scRNA-seq
Ulrich, N. D.; Shen, Y.-c.; Ma, Q.; Yang, K.; Hannum, D. F.; Jones, A.; Machlin, J.; Randolph, J. F.; Smith, Y. R.; Schon, S. B.; Shikanov, A.; Marsh, E. E.; Li, J.; Hammoud, S.
10.1101/2021.09.16.460628 — systems biology — Posted on 2021-09-17
1710 The Barley HvSTP13GR mutant triggers resistance against biotrophic fungi
Skoppek, C. I.; Punt, W.; Heinrichs, M.; Ordon, F.; Wehner, G.; Boch, J.; Streubel, J.
10.1101/2021.09.16.460598 — plant biology — Posted on 2021-09-17
1711 A Novel Model of Estrogen Receptor-Positive Breast Cancer Bone Metastasis with Antiestrogen Responsiveness
Langsten, K. L.; Shi, L.; Wilson, A. S.; Westwood, B.; Xie, M. T.; Surratt, V. E.; Turner, J.; Singh, R.; Cook, K. L.; Kerr, B. A.
10.1101/2021.09.16.460665 — cancer biology — Posted on 2021-09-17
1716 Placental gene expression-based cell type deconvolution: Cell proportions drive preeclampsia gene expression differences
Campbell, K. A.; Colacino, J. A.; Puttabyatappa, M.; Dou, J.; Elkin, E. R.; Hammoud, S. S.; Domino, S. E.; Dolinoy, D. C.; Goodrich, J. M.; Loch-Caruso, R.; Padmanabhan, V.; Bakulski, K. M.
10.1101/2021.07.29.454041 — developmental biology — Posted on 2021-09-17
1717 Gp78-mediated basal mitophagy promotes mitochondrial health and limits mitochondrial ROS production
Alan, P.; Joshi, B.; Cardoen, B.; Vandevoorde, K. R.; Gao, G.; Mohammadzadeh, Y.; Hamarneh, G.; Nabi, I. R.
10.1101/2021.09.17.460825 — cell biology — Posted on 2021-09-17
1718 Therapeutic anti-PD-L1 antibody affects ESCRT-mediated functions in cells expressing oncogenic EGFR.
Letian, A.; Yemanaberhan, E.; Cavaliere, P.; Dephoure, N.; Altorki, N. K.; McGraw, T. E.
10.1101/2021.09.17.460833 — cell biology — Posted on 2021-09-17
1720 Metabolic diversity and aero-tolerance in anammox bacteria from geochemically distinct aquifers
Mosley, O. E.; Gios, E.; Weaver, L.; Close, M.; Daughney, C.; van der Raaij, R.; Martindale, H.; Handley, K. M.
10.1101/2021.09.16.460709 — microbiology — Posted on 2021-09-17
1722 Effects of early life adversity on meningeal mast cells and proinflammatory gene expression in male and female Mus musculus
Duque-Wilckens, N.; Sarno, E.; Teis, R.; Stoelting, F.; Khalid, S.; Dairi, Z.; Douma, A.; Maradiaga, N.; Thelen, K.; Robison, A. J.; Moeser, A.
10.1101/2021.09.17.460793 — immunology — Posted on 2021-09-17
1725 m6A modifications regulate intestinal immunity and rotavirus infection
Zhu, S.; Wang, A.; Wang, J.; Tao, W.; Ding, S.; Flavell, R. A.; Tong, J.; Hou, G.; Gao, J.; Zhang, G.; Li, R.; Ren, X.; Wang, D.; Zhang, K.; Pan, W.; Li, H.; Qian, C.
10.1101/2021.09.17.460776 — immunology — Posted on 2021-09-17
1728 Visual QC Protocol for FreeSurfer Cortical Parcellations from Anatomical MRI
Raamana, P. R.; Theyers, A.; Selliah, T.; Bhati, P.; Arnott, S. R.; Hassel, S.; Nanayakkara, N. D.; Scott, C. J. M.; Harris, J.; Zamyadi, M.; Lam, R. W.; Milev, R.; Mueller, D. J.; Rotzinger, S.; Frey, B. N.; Kennedy, S. H.; Black, S. E.; Lang, A.; Masellis, M.; Symons, S.; Bartha, R.; MacQueen, G. M.; CANBIND Investigator Team, ; ONDRI Study Group, ; Strother, S. C.
10.1101/2020.09.07.286807 — neuroscience — Posted on 2021-09-17
1732 Ethylene-triggered subcellular trafficking of CTR1 enhances the response to ethylene gas
Lee, H. Y.; Seo, D. H.; Park, H. L.; Bakshi, A.; Park, C.; Kieber, J. J.; Binder, B. M.; Yoon, G.
10.1101/2020.06.12.148858 — plant biology — Posted on 2021-09-17
1733 AHK5 mediates ETR1-initiated multistep phosphorelay in Arabidopsis
Szmitkowska, A.; Cuyacot, A. R.; Pekarova, B.; Zdarska, M.; Houser, J.; Komarek, J.; Jasenakova, Z.; Jayasree, A.; Heunemann, M.; Ubogoeva, E.; Spyoglou, I.; Trtilek, M.; Mironova, V.; Harter, K.; Zemlyanskaya, E.; Zidek, L.; Wimmerova, M.; Hejatko, J.
10.1101/2021.09.16.460643 — plant biology — Posted on 2021-09-17
1735 Pharmacological rescue of tumor intrinsic STING expression and immune response in LKB1-mutant lung cancer via the IAP-JAK regulatory axis
Shu, C.; Jin, R.; Niu, Q.; Cicka, D.; Doyle, S.; Wahafu, A.; Fan, D.; Zheng, X.; Du, Y.; Ivanov, A.; Doxie, D.; Dhodapkar, K.; Carlisle, J.; Owonikoko, T.; Ramalingam, S.; Sica, G.; Dhodapkar, M.; Zhou, W.; Mo, X.; Fu, H.
10.1101/2021.09.17.460294 — cancer biology — Posted on 2021-09-17
1738 Kalium rhodopsins: Natural light-gated potassium channels
Govorunova, E. G.; Gou, Y.; Sineshchekov, O. A.; Li, H.; Wang, Y.; Brown, L. S.; Xue, M.; Spudich, J. L.
10.1101/2021.09.17.460684 — biochemistry — Posted on 2021-09-17
1743 A distinctive ligand recognition mechanism by the human vasoactive intestinal polypeptide receptor 2
Xu, Y.; Feng, W.; Zhou, Q.; Liang, A.; Li, J.; Dai, A.; Zhao, F.; Zhao, L.; Xia, T.; Jiang, Y.; Xu, H. E.; Yang, D.; Wang, M.-W.
10.1101/2021.09.16.460712 — molecular biology — Posted on 2021-09-17
1745 Structural and functional characterization of Rv0792c from Mycobacterium tuberculosis: identifying small molecule inhibitors against GntR protein.
Chauhan, N. K.; Anand, A.; Sharma, A.; Dhiman, K.; Gosain, T. P.; Singh, P.; Khan, E.; Kumar, A.; Sharma, D.; Ganguly, A.; Sharma, T. K.; Singh, R.
10.1101/2021.09.17.460839 — microbiology — Posted on 2021-09-17
1748 Zoonotic potential of a novel bat morbillivirus
Ikegame, S.; Carmichael, J. C.; Wells, H.; Furler, R. L.; Acklin, J. A.; Chiu, H.-P.; Oguntuyo, K. Y.; Cox, R. M.; Patel, A. R.; Kowdle, S.; Stevens, C. S.; Eckley, M.; Zhan, S.; Lim, J. K.; Hashiguchi, T.; Durigon, E. L.; Schountz, T.; Epstein, J. E.; Plemper, R. K.; Daszak, P.; Anthony, S. J.; Lee, B.
10.1101/2021.09.17.460143 — microbiology — Posted on 2021-09-17
1749 Quantifying the impact of gut microbiota on inflammation and hypertensive organ damage
Avery, E. G.; Bartolomaeus, H.; Rauch, A.; Chen, C.-Y.; N'diaye, G.; Loeber, U.; Bartolomaeus, T. U.; Fritsche-Guenther, R.; Rodrigues, A. F.; Tsvetkov, D.; Todiras, M.; Park, J.-K.; Marko, L.; Maifeld, A.; Bader, M.; Kempa, S.; Kirwan, J. A.; Forslund, S. K.; Muller, D. N.; Wilck, N.
10.1101/2021.09.17.460671 — microbiology — Posted on 2021-09-17
1750 Long-term Motor Learning in the Wild with High Volume Video Game Data
Listman, J. B.; Tsay, J.; Kim, H. E.; Mackey, W. E.; Heeger, D. J.
10.1101/2021.09.15.460516 — neuroscience — Posted on 2021-09-17
1751 3D-imaging inspired improvements to hearing model in parasitoid fly Ormia ochracea
Mikel-Stites, M.; Salcedo, M.; Socha, J. J.; Marek, P. E.; Staples, A. E.
10.1101/2021.09.15.460520 — biophysics — Posted on 2021-09-17
1752 The effect of mating complexity on gene drive dynamics
Verma, P.; Reeves, R. G.; Simon, S.; Otto, M.; Gokhale, C. S.
10.1101/2021.09.16.460618 — evolutionary biology — Posted on 2021-09-17
1761 Metabolic Derangement in Polycystic Kidney Disease Mouse Models Is Ameliorated by Mitochondrial-Targeted Antioxidants
Daneshgar, N.; Baguley, A. W.; Liang, P.-I.; Wu, F.; Chu, Y.; Kinter, M. T.; Benavides, G. A.; Johnson, M. S.; Darley-Usmar, V.; Zhang, J.; Chan, K.-S.; Dai, D.-F.
10.1101/2021.09.15.460510 — pathology — Posted on 2021-09-17
1762 Tourmaline: a workflow for rapid and reproducible amplicon sequence analysis using QIIME 2 and Snakemake
Thompson, L. R.; Anderson, S. R.; Den Uyl, P. A.; Patin, N. V.; Sanderson, G.; Goodwin, K. D.
10.1101/2021.09.15.460495 — bioinformatics — Posted on 2021-09-17
1765 Modelling potential range expansion of an underutilised food security crop in Sub-Saharan Africa
Koch, O.; Mengesha, W. A.; Pironon, S.; Pagella, T.; Ondo, I.; Rosa, I.; Wilkin, P.; Borrell, J. S.
10.1101/2021.09.15.460440 — ecology — Posted on 2021-09-17
1766 Global trade-offs in tree functional traits
Maynard, D. S.; Bialic-Murphy, L.; Zohner, C. M.; Averill, C.; van den Hoogen, J.; Ma, H.; Mo, L.; Smith, G. R.; Aubin, I.; Berenguer, E.; Boonman, C. C. F.; Catford, J.; Cerabolini, B. E. L.; Dias, A.; Gonzalez-Melo, A.; Heitz, P.; Lusk, C. H.; Mori, A. S.; Niinemets, U.; Pillar, V. D.; Rosell, J. A.; Schurr, F. M.; Sheremetev, S. N.; da Silva, A. C.; Sosinski, E.; van Bodegom, P. M.; Weiher, E.; Bönisch, G.; Kattge, J.; Crowther, T. W.
10.1101/2021.09.16.458157 — ecology — Posted on 2021-09-17
1768 White Matter Signals Reflect Information Transmission Between Brain Regions During Seizures
Revell, A. Y.; Silva, A. B.; Mahesh, D.; Armstrong, L.; Arnold, T. C.; Bernabei, J. M.; Stein, J. M.; Das, S. R.; Shinohara, R. T.; Bassett, D. S.; Litt, B.; Davis, K. A.
10.1101/2021.09.15.460549 — neuroscience — Posted on 2021-09-17
1770 Alzheimer's disease alters astrocytic functions related to neuronal support andtranscellular internalization of mitochondria
Lampinen, R.; Belaya, I.; Saveleva, L.; Liddell, J. R.; Rait, D.; Huuskonen, M. T.; Giniatullina, R.; Sorvari, A.; Soppela, L.; Mikhailov, N.; Boccuni, I.; Giniatullin, R.; Cruz-Haces, M.; Konovalova, J.; Koskuvi, M.; Rauramaa, T.; Domanskyi, A.; Hamalainen, R. H.; Goldsteins, G.; Koistinaho, J.; Malm, T.; Chew, S.; Rilla, K.; White, A. R.; Marsh-Armstrong, N.; Kanninen, K. M.
10.1101/2021.09.15.460570 — neuroscience — Posted on 2021-09-17
1771 ppGpp Is Present in, and Regulates Sleep of, Drosophila
Rao, Y.; Young, W.; Zhang, X.; Dai, H. X.; Zhou, E.; Zhang, W.
10.1101/2021.09.16.460595 — neuroscience — Posted on 2021-09-17
1774 Deletion or inhibition of astrocytic transglutaminase 2 promotes functional recovery after spinal cord injury
Elahi, A.; Emerson, J.; Rudlong, J.; Keillor, J. W.; Salois, G.; Visca, A.; Girardi, P.; Johnson, G. V.; Proschel, C.
10.1101/2021.09.15.460455 — neuroscience — Posted on 2021-09-17
1775 Combi-Seq: Multiplexed transcriptome-based profiling of drug combinations using 1deterministic barcoding in single-cell droplets
Mathur, L.; Szalai, B.; Utharala, R.; Ballinger, M.; Jonathan, J. J.; Ryckelynck, M.; Benes, V.; Saez-Rodriguez, J.; Merten, C. A.
10.1101/2021.09.16.460212 — systems biology — Posted on 2021-09-17
1776 Water stress-associated isolation barriers between two sympatric oak species
LE PROVOST, G.; Brachi, B.; Lesur, I.; Lalanne, C.; Labadie, K.; Aury, J. M.; Da Silva, C.; Postolache, D.; Leroy, T.; Plomion, C.
10.1101/2021.09.16.460585 — plant biology — Posted on 2021-09-17
1777 Hepatocyte serine palmitoyl transferase 2 deficiency promotes liver C16:0-ceramide accumulation through sphingomyelin hydrolysis and leads to liver damage and dysfunction in mice
Lallement, J.; Raho, I.; Merlen, G.; Rainteau, D.; Croyal, M.; Schiffano, M.; Kassis, N.; Doignon, I.; Soty, M.; Krempf, M.; Amouyal, C.; Le Stunff, H.; Magnan, C.; Tordjmann, T.; Cruciani-Guglielmacci, C.
10.1101/2021.09.16.460588 — physiology — Posted on 2021-09-17
1778 Adipocyte-specific modulation of KLF14 expression in mice leads to sex-dependent impacts in adiposity and lipid metabolism
Yang, Q.; Hinkle, J.; Reed, J. N.; Aherrahrou, R.; Xu, Z.; Harris, T. E.; Stephenson, E. E.; Musunuru, K.; Keller, S. R.; Civelek, M.
10.1101/2021.09.15.460489 — physiology — Posted on 2021-09-17
1779 Adiponectin receptor agonist AdipoRon improves skeletal muscle function in aged mice
Balasubramanian, P.; Schaar, A. E.; Gustafson, G. E.; Smith, A. B.; Howell, P. R.; Greenman, A.; Baum, S.; Colman, R. J.; Lamming, D. W.; Diffee, G. M.; Anderson, R.
10.1101/2021.09.16.460597 — physiology — Posted on 2021-09-17
1781 Developing selective FPR2 agonists can be a potential approach to treat moderate to severe asthma.
Visaga, S. A.; Kalonia, H.; Verma, V.; Sinha, S.; Singh, S. K.; Upadhyay, S.; Sahdev, S.; Pansari, A.; Kumar, R.; Bandgar, M.; Karanjule, N.; Shirumalla, R. K.; Morishita, K.; Tandon, R.
10.1101/2021.09.16.460577 — pharmacology and toxicology — Posted on 2021-09-17
1782 Acoustic array biochip combined with allele-specific PCR for multiple cancer mutation analysis in tissue and liquid biopsy
Naoumi, N.; Michaelidou, K.; Papadakis, G.; Simaiaki, A. E.; Fernandez, R.; Calero, M.; Arnau, A.; Tsortos, A.; Agelaki, S.; Gizeli, E.
10.1101/2021.09.16.460590 — biophysics — Posted on 2021-09-17
1784 OmicsView: omics data analysis through interactive visual analytics
Casey, F.; Negi, S.; Zhu, J.; Zavodszky, M. I.; Cheng, D.; Lin, D.; John, S.; Penny, M.; Sexton, D.; Zhang, B.
10.1101/2021.09.15.460469 — bioinformatics — Posted on 2021-09-17
1785 Accurate Name Entity Recognition for Biomedical Literatures: A Combined High-quality Manual Annotation and Deep-learning Natural Language Processing Study
Huang, D.-L.; Zeng, Q.; Xiong, Y.; Liu, S.; Pang, C.; Xia, M.; Fang, T.; Ma, Y.; Qiang, C.; Zhang, Y.; Zhang, Y.; Li, H.; Yuan, Y.
10.1101/2021.09.15.460567 — bioinformatics — Posted on 2021-09-17
1786 Vascular lung triculture organoid via soluble extracellular matrix suspension
Valdoz, J. C.; Franks, N. A.; Cribbs, C. G.; Jacobs, D. J.; Dodson, E. L.; Knight, C. J.; Poulson, P. D.; Garfield, S. R.; Johnson, B. C.; Hemeyer, B. M.; Sudo, M. T.; Saunooke, J. A.; Vallecillo-Zuniga, M. L.; Santos, M.; Chamberlain, B.; Christensen, K. A.; Nordin, G. P.; Raghu, G.; Van Ry, P. M.
10.1101/2021.09.16.460165 — bioengineering — Posted on 2021-09-17
1791 Environmental correlates and functional consequences of bill divergence in island song sparrows
Gamboa, M. P.; Ghalambor, C. K.; Sillett, T. S.; Funk, W. C.; Furbush, R. A.; Husak, J. F.; Danner, R. M.
10.1101/2021.09.15.460486 — ecology — Posted on 2021-09-17
1794 Computational capability of ecological dynamics
Ushio, M.; Watanabe, K.; Fukuda, Y.; Tokudome, Y.; Nakajima, K.
10.1101/2021.09.15.460556 — ecology — Posted on 2021-09-17
1796 Cbp1, a rapidly evolving fungal virulence factor, forms an effector complex that drives macrophage lysis
Azimova, D.; Herrera, N.; Duvenage, L.; Voorhies, M.; English, B. C.; Hoving, J. C.; Oren, R.; Sil, A.
10.1101/2021.09.16.459956 — microbiology — Posted on 2021-09-17
1797 Biomechanical interactions of Schistosoma mansoni eggs with vascular endothelial cells facilitate egg extravasation
Yeh, Y.-T.; Skinner, D. E.; Criado-Hidalgo, E.; Chen, N. S.; Garcia-De Herreros, A.; El-Sakary, N.; Liu, L.; Zhang, S.; Chien, S.; Lasheras, J. C.; del Alamo, J. C.; Caffrey, C. R.
10.1101/2021.09.16.459846 — microbiology — Posted on 2021-09-17
1800 Lifelong musical activity is associated with multi-domain cognitive and brain benefits in older adults
Boettcher, A.; Zarucha, A.; Koebe, T.; Gaubert, M.; Hoeppner, A.; Fabel, K.; Altenstein, S.; Bartels, C.; Buerger, K.; Dechent, P.; Dobisch, L.; Ewers, M.; Fliessbach, K.; Freiesleben, S. D.; Frommann, I.; Haynes, J.-D.; Janowitz, D.; Kilimann, I.; Kleineidam, L.; Laske, C.; Maier, F.; Metzger, C.; Munk, M.; Perneczky, R.; Peters, O.; Priller, J.; Rauchmann, B.-S.; Roy, N.; Scheffler, K.; Schneider, A.; Spottke, A.; Teipel, S. J.; Wolfsgruber, S.; Wiltfang, J.; Yakupov, R.; Duzel, E.; Jessen, F.; Roeske, S.; Wagner, M.; Kempermann, G.; Wirth, M.; DELCODE study group,
10.1101/2021.09.15.460202 — neuroscience — Posted on 2021-09-17
1801 The rt-TEP tool: real-time visualization of TMS-evoked potentials to maximize cortical activation and minimize artifacts
Casarotto, S.; Fecchio, M.; Rosanova, M.; Varone, G.; D'Ambrosio, S.; Sarasso, S.; Pigorini, A.; Russo, S.; Comanducci, A.; Ilmoniemi, R. J.; Massimini, M.
10.1101/2021.09.15.460488 — neuroscience — Posted on 2021-09-17
1805 Multimodal Detection of Dopamine by Sniffer Cells Expressing Genetically Encoded Fluorescence Sensors
Herenbrink, C. K.; Stoier, J. F.; Reith, W. D.; Dagra, A.; Gregorek, M. A. C.; Li, Y.; Tian, L.; Gether, U.; Herborg, F.
10.1101/2021.09.16.460471 — neuroscience — Posted on 2021-09-17
1808 Tuna-AI: tuna biomass estimation with Machine Learning models trained on oceanography and echosounder FAD data
Precioso, D.; Navarro-Garcia, M.; Gavira-O'Neill, K.; Torres-Barran, A.; Gordo, D.; Gallego-Alcala, V.; Gomez-Ullate, D.
10.1101/2021.09.15.460261 — bioinformatics — Posted on 2021-09-17
1813 Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad
Mayere, C.; Regard, V.; Perea-Gomez, A.; Bunce, C.; Neirijnck, Y.; Djari, C.; Sararols, P.; Reeves, R.; Greenaway, S.; Simon, M.; Siggers, P.; Condrea, D.; Kühne, F.; Gantar, I.; Tang, F.; Stevant, I.; Batti, L.; Ghyselinck, N. B.; Wilhelm, D.; Greenfield, A.; Capel, B.; Chaboissier, M.-C.; Nef, S.
10.1101/2021.09.15.460431 — developmental biology — Posted on 2021-09-17
1815 The Physiological Landscape and Specificity of Antibody Repertoires
Csepregi, L.; Hoehn, K. B.; Neumeier, D.; Taft, J. M.; Friedensohn, S.; Weber, C. R.; Kummer, A.; Sesterhenn, F.; Correia, B. E.; Reddy, S. T.
10.1101/2021.09.15.460420 — immunology — Posted on 2021-09-17
1816 High-order functional interactions in ageing explained via alterations in the connectome in a whole-brain model
Gatica, M.; Rosas, F. E.; Mediano, P. A. M.; Diez, I.; Swinnen, S. P.; Orio, P.; Cofre, R.; Cortes, J. M.
10.1101/2021.09.15.460435 — neuroscience — Posted on 2021-09-17
1819 β-Catenin-NFκB-CFTR interactions in cholangiocytes regulate inflammation and fibrosis during ductular reaction
Hu, S.; Russell, J.; Liu, S.; Rai, R.; Kosar, K.; Tao, J.; Hurley, E.; Poddar, M.; Singh, S.; Bell, A.; Shin, D.; Raeman, R.; Singhi, A.; Nejak-Bowen, K.; ko, S.; P Monga, S.
10.1101/2021.09.15.460429 — pathology — Posted on 2021-09-17
1821 The nuts and bolts of SARS-CoV-2 Spike Receptor Binding Domain heterologous expression
Maffei, M.; Montemiglio, L. C.; Vitagliano, G.; Fedele, L.; Sellathurai, S.; Bucci, F.; Compagnone, M.; Chiarini, V.; Exertier, C.; Muzi, A.; Roscilli, G.; Vallone, B.; Marra, E.
10.1101/2021.09.17.460782 — biochemistry — Posted on 2021-09-17
1822 A novel hamster model of SARS-CoV-2 respiratory infection using a pseudotyped virus
Yamada, H.; Sasaki, S.; Tani, H.; Somekawa, M.; Kawasuji, H.; Saga, Y.; Yoshida, Y.; Yamamoto, Y.; Hayakawa, Y.; Morinaga, Y.
10.1101/2021.09.17.460745 — microbiology — Posted on 2021-09-17
1823 ZRC3308 monoclonal antibody cocktail shows protective efficacy in Syrian hamsters against SARS-CoV-2 infection
Yadav, P.; Mendiratta, S. K.; Mohandas, S.; Singh, A. K.; Abraham, P.; Shete, A.; Bandhyopadhyay, S.; Kumar, S.; Parikh, A.; Kalita, P.; Sharma, V.; Pandya, H.; Patel, C. G.; Patel, M.; Soni, S.; Giri, S.; Jain, M.
10.1101/2021.09.16.460724 — microbiology — Posted on 2021-09-17
1824 Small molecule screen employing patient-derived iPS hepatocytes identifies LRRK2 as a novel therapeutic target for Alpha1 Antitrypsin Deficiency
Kent, D.; Ng, S. S.; Khoshkenar, P.; Syanda, A. M.; Chao Zheng, L.; Zieger, M.; Greer, C.; Hatch, S. B.; Segal, J. M.; Blackford, S. J. I.; Chowdary, V.; Ismali, T.; Danovi, D.; Sahdeo, S.; Ebner, D.; Mueller, C.; Rashid, S. T.
10.1101/2021.09.17.460732 — cell biology — Posted on 2021-09-17
1825 Proteomic Characterization of Isolated Arabidopsis Clathrin-Coated Vesicles Reveals Evolutionarily Conserved and Plant Specific Components
Dahhan, D. A.; Reynolds, G. D.; Cardenas, J. J.; Eeckhout, D.; Johnson, A.; Yperman, K.; Kaufmann, W.; Vang, N.; Yan, X.; Hwang, I.; Heese, A.; De Jaeger, G.; Friml, J.; Van Damme, D.; Pan, J.; Bednarek, S. Y.
10.1101/2021.09.16.460678 — cell biology — Posted on 2021-09-17
1826 C-type natriuretic peptide facilitates autonomic Ca2+ entry in growth plate chondrocytes for stimulating bone growth
Miyazaki, Y.; Ichimura, A.; Kitayama, R.; Okamoto, N.; Yasue, T.; Liu, F.; Ueda, Y.; Yamauchi, I.; Hakata, T.; Nakao, K.; Kakizawa, S.; Nishi, M.; Mori, Y.; Akiyama, H.; Nakao, K.; Takeshima, H.
10.1101/2021.09.17.460760 — cell biology — Posted on 2021-09-17
1827 IRE1α drives lung epithelial progenitor dysfunction to establish a niche for pulmonary fibrosis
Auyeung, V. C.; Downey, M. S.; Kathiriya, J. J.; Thamsen, M.; Wenger, T. A.; Backes, B. J.; Brumwell, A.; Chapman, H. A.; Sheppard, D.; Papa, F. R.
10.1101/2021.09.16.460705 — cell biology — Posted on 2021-09-17
1828 The beta-tubulin isotype TUBB6 controls microtubule and actin dynamics in osteoclasts.
Maurin, J.; Morel, A.; Guerit, D.; Cau, J.; Urbach, S.; BLANGY, A.; Bompard, G.
10.1101/2021.09.17.460637 — cell biology — Posted on 2021-09-17
1829 The solute carrier MFSD1 decreases β1 integrins activation status and thus tumor metastasis
Roblek, M.; Bicher, J.; van Gogh, M.; Gyoergy, A.; Seeboeck, R.; Szulc, B.; Damme, M.; Olczak, M.; Borsig, L.; Siekhaus, D.
10.1101/2021.09.17.460743 — cancer biology — Posted on 2021-09-17
1830 SARS-CoV-2 Neutralization in Commercial Lots of Plasma-derived Immunoglobulin
Volk, A.; Covini-Souris, C.; Kuehnel, D.; de Mey, C.; Roemisch, J.; Schmidt, T.
10.1101/2021.08.13.456066 — immunology — Posted on 2021-09-17
1831 A genetic trap in yeast for inhibitors of SARS-CoV-2 main protease
Alalam, H.; Sigurdardottir, S.; Bourgard, C.; Tiukova, I. A.; King, R. D.; Grötli, M.; Sunnerhagen, P.
10.1101/2021.09.14.460411 — synthetic biology — Posted on 2021-09-17
1832 Real-time monitoring and analysis of SARS-CoV-2 nanopore sequencing with minoTour.
Munro, R. J.; Holmes, N.; Moore, C.; Carlile, M.; Payne, A.; Santos, R.; Loose, M. W.
10.1101/2021.09.13.459777 — bioinformatics — Posted on 2021-09-17
1836 Seasonal temporal dynamics of marine protists communities in tidally mixed coastal waters
Caracciolo, M.; Rigaut-Jalabert, F.; Romac, S.; Mahe, F.; Forsans, S.; Gac, J.-P.; Arsenieff, L.; Manno, M.; Chaffron, S.; Cariou, T.; Hoebeke, M.; Bozec, Y.; Goberville, E.; Le Gall, F.; Guilloux, L.; Baudoux, A.-C.; de Vargas, C.; Not, F.; Thiebaut, E.; Henry, N.; Simon, N.
10.1101/2021.09.15.460302 — ecology — Posted on 2021-09-17
1837 Therapeutic efficacy of an oral nucleoside analog of remdesivir against SARS-CoV-2 pathogenesis in mice.
Schafer, A.; Martinez, D. R.; Won, J. J.; Moreira, F. R.; Brown, A. J.; Gully, K. L.; Kalla, R.; Chun, K.; Du Pont, V.; Babusis, D.; Tang, J.; Murakami, E.; Subramanian, R.; Barrett, K. T.; Bleier, B. J.; Bannister, R.; Feng, J. Y.; Bilello, J. P.; Cihlar, T.; Mackman, R. L.; Montgomery, S. A.; Baric, R. S.; Sheahan, T. P.
10.1101/2021.09.13.460111 — microbiology — Posted on 2021-09-17
1839 Stabilization of spine Synaptopodin by mGluR1 is required for mGluR-LTD
Speranza, L.; Inglebert, Y.; De Sanctis, C.; Wu, P. Y.; Kalinowska, M.; McKinney, R. A.; Francesconi, A.
10.1101/2021.09.14.460352 — neuroscience — Posted on 2021-09-17
1844 A structured evaluation of cryopreservation in generating single cell transcriptomes from cerebrospinal fluid
Touil, H.; Roostaei, T.; Calini, D.; Diaconu, C.; Epstein, S. E.; Raposo, C.; Craveiro, L.; Callegiri, I.; Bryois, J.; Riley, C. S.; Menon, V.; Derfuss, T.; De Jager, P.; Malhotra, D.
10.1101/2021.09.15.460354 — genetics — Posted on 2021-09-17
1846 Uterus-specific transcriptional regulation underlies eggshell pigment production in Japanese quail
Ishishita, S.; Kitahara, S.; Takahashi, M.; Iwasaki, S.; Tatsumoto, S.; Hara, I.; Kaneko, Y.; Kinoshita, K.; Yamaguchi, K.; Harada, A.; Ohmori, Y.; Ohkawa, Y.; Go, Y.; Shigenobu, S.; Matsuda, Y.; Suzuki, T.
10.1101/2021.09.15.460419 — genetics — Posted on 2021-09-17
1848 WIN 55,212-2 shows anti-inflammatory and survival properties in human iPSC-derived cardiomyocytes infected with SARS-CoV-2
Aragao, L. G. H. S.; Oliveira, J. T.; Temerozo, J. R.; Mendes, M. A.; Salerno, J. A.; Pedrosa, C. d. S. G.; Puig-Pijuan, T.; Verissimo, C.; Ornelas, I. M.; Torquato, T.; Vitoria, G.; Sacramento, C. Q.; Fintelman-Rodrigues, N.; Dias, S. d. S. G.; Cardoso Soares, V.; Souza, L. R. Q.; Karmirian, K.; Goto-Silva, L.; Biagi, D.; Cruvinel, E. M.; Dariolli, R.; Furtado, D. R.; Bozza, P. T.; Borges, H. L.; Souza, T. M. L.; Guimaraes, M. Z. P.; Rehen, S.
10.1101/2021.02.20.431855 — cell biology — Posted on 2021-09-17
1849 Immunoglobulin enhancers increase RNA polymerase stalling at somatic hypermutation target sequences
Tarsalainen, A.; Maman, Y.; Meng, F.-L.; Kylaniemi, M. K.; Soikkeli, A.; Budzynska, P.; McDonald, J. J.; Senigl, F.; Alt, F. W.; Schatz, D. G.; Alinikula, J.
10.1101/2021.09.16.460442 — immunology — Posted on 2021-09-17
1850 Epigenetic Remodeling by Vitamin C Potentiates the Differentiation of Mouse and Human Plasma Cells
Chen, H.-Y.; Almonte-Loya, A.; Lay, F.-Y.; Johnson, E.; Gonzalez-Avalos, E.; Yin, J.; Ma, Q.; Wozniak, D. J.; Harrison, F. E.; Lio, C.-W. J.
10.1101/2021.09.15.460473 — immunology — Posted on 2021-09-17
1851 The cellular architecture of microvessels, pericytes and neuronal cell types in organizing regional brain energy homeostasis in mice
Wu, Y.-t.; Bennett, H. C.; Chon, U.; Vanselow, D. J.; Zhang, Q.; Munoz-Castaneda, R.; Cheng, K. C.; Osten, P.; Drew, P. J.; Kim, Y.
10.1101/2021.05.19.444854 — neuroscience — Posted on 2021-09-17
1853 Condensin compacts DNA in 15 nm steps and requires FACT for extrusion on chromatin
Sudhakar, S.; Fisher, G. L.; Escribano, P. G.; Luis, J. G.; Cutts, E.; Cawood, C.; Aragon, L.; Rueda, D. S.
10.1101/2021.09.15.460217 — biophysics — Posted on 2021-09-17
1856 Antithrombin glycoforms are selectively physiosorbed on plasma extracellular vesicles
Radeghieri, A.; Alacqua, S.; Zendrini, A.; Previcini, V.; Todaro, F.; Martini, G.; Ricotta, D.; Bergese, P.
10.1101/2021.07.16.452649 — biochemistry — Posted on 2021-09-17
1860 Drosophila nicotinic acetylcholine receptors and their interactions with insecticidal peptide toxins
Korona, D.; Dirnberger, B.; Giachello, C. N. G.; Queiroz, R. M. L.; Minde, D.-P.; Deery, M. J.; Johnson, G.; Mueller, K. H.; Firth, L. C.; Earley, F. G.; Russell, S.; Lilley, K. S.
10.1101/2021.08.13.456240 — neuroscience — Posted on 2021-09-17
1862 homeRNA: A self-sampling kit for the collection of peripheral blood and stabilization of RNA
Haack, A. J.; Lim, F. Y.; Kennedy, D. S.; Day, J. H.; Adams, K. N.; Lee, J. J.; Berthier, E.; Theberge, A. B.
10.1101/2021.02.08.430337 — bioengineering — Posted on 2021-09-17
1864 Comparative transcriptomics of seven Impatiens species
Surinova, M.; Stoces, S.; Dostalek, T.; Jarosova, A.; Münzbergova, Z.
10.1101/2021.09.16.460688 — plant biology — Posted on 2021-09-16
1865 Dysregulation of the Tweak/Fn14 pathway in skeletal muscle of spinal muscular atrophy mice
Meijboom, K. E.; McFall, E.; Anthony, D.; Edwards, B.; Kubinski, S.; Hazell, G.; Ahlskog, N.; Claus, P.; Davies, K. E.; Kothary, R.; Wood, M.; Bowerman, M.
10.1101/2021.09.13.460053 — pathology — Posted on 2021-09-16
1867 Kinetics of the inflammatory response during experimental Babesia rossi infection of beagle dogs
Atkinson, B. K.; Thompson, P.; Van Zyl, E.; Goddard, A.; Rautenbach, Y.; Schoeman, J. P.; Mukorera, V.; Leisewitz, A.
10.1101/2021.09.16.460686 — immunology — Posted on 2021-09-16
1870 Feeding ecology of broadbill swordfish (Xiphias gladius) in the California Current
Preti, A.; Stohs, S. M.; DiNardo, G. T.; Saavedra, C.; MacKenzie, K.; Noble, L. R.; Jones, C. S.; Pierce, G. J.
10.1101/2021.09.16.460689 — ecology — Posted on 2021-09-16
1872 Large-scale allosteric switch in the 7SK RNA regulates transcription in response to growth and stress
Olson, S. W.; Turner, A.-M. W.; Arney, J. W.; Saleem, I.; Weidmann, C. A.; Margolis, D. M.; Weeks, K. M.; Mustoe, A. M.
10.1101/2021.09.16.460563 — biochemistry — Posted on 2021-09-16
1874 FGF21-FGFR4 signaling in cardiac myocytes promotes concentric cardiac hypertrophy in mouse models of diabetes
Yanucil, C.; Kentrup, D.; Li, X.; Grabner, A.; Schramm, K.; Martinez, E.; Li, J.; Campos, I.; Czaya, B.; Heitman, K.; Westbrook, D.; Wende, A.; Sloan, A.; Roche, J.; Fornoni, A.; Kapiloff, M. S.; Faul, C.
10.1101/2021.09.16.460632 — molecular biology — Posted on 2021-09-16
1875 Regulating expression of mistranslating tRNAs by readthrough RNA polymerase II transcription
Berg, M. D.; Isaacson, J. R.; Cozma, E.; Genereaux, J.; Lajoie, P.; Villen, J.; Brandl, C. J.
10.1101/2021.09.16.460584 — molecular biology — Posted on 2021-09-16
1876 Paving the way towards understanding the inflammatory pathways triggered by giant viruses in mammalian cells: effect of mimivirus-cell interactions on IκBα degradation
Oliveira, J. d. S.; Oliveira, D. F.; Essus, V. A.; Nunes, G. H. P.; Honorato, L.; Oliveira, L.; Nimrichter, L.; Peralta, J. M.; Guimaraes, A. J.; Foguel, D.; Cortines, J. R.
10.1101/2021.09.16.460633 — microbiology — Posted on 2021-09-16
1877 Acidity and sulfur oxidation intermediate concentrations controlled by O2-driven partitioning of sulfur oxidizing bacteria in a mine tailings impoundment
Whaley-Martin, K. J.; Chen, L.-X.; Colebrander Nelson, T.; Gordon, J.; Kantor, R.; Twible, L. E.; Marshall, S.; Rossi, L.; Bessette, B.; Baron, C.; Apte, S.; Banfield, J.; Warren, L. A.
10.1101/2021.09.16.460096 — microbiology — Posted on 2021-09-16
1881 Engineered bacteria detect tumor DNA in vivo
Cooper, R. M.; Wright, J. A.; Ng, J. Q.; Goyne, J. M.; Suzuki, N.; Lee, Y. K.; Ichinose, M.; Radford, G.; Thomas, E. M.; Vrbanac, L.; Knight, R.; Woods, S. L.; Worthley, D. L.; Hasty, J.
10.1101/2021.09.10.459858 — synthetic biology — Posted on 2021-09-16
1882 The polyol pathway is an evolutionarily conserved system for sensing glucose uptake
Sano, H.; Nakamura, A.; Yamane, M.; Niwa, H.; Nishimura, T.; Araki, K.; Takemoto, K.; Ishiguro, K.-i.; Aoki, H.; Kojima, M.
10.1101/2021.09.14.460366 — physiology — Posted on 2021-09-16
1883 Maternal obesity causes fetal cardiac hypertrophy and alters adult offspring myocardial metabolism in mice
Vaughan, O. R.; Rosario, F.; Chan, J.; Cox, L. A.; Ferchaud-Roucher, V.; Zemski-Berry, K.; Reusch, J.; Keller, A.; Powell, T.; Jansson, T.
10.1101/2021.09.15.460457 — physiology — Posted on 2021-09-16
1884 Structural transitions permitting ligand entry and exit in bacterial fatty acid binding proteins.
White, S. W.; Rock, C. O.; Tajkhorshid, E.; Gullett, J. M.; Cuypers, M. G.; Grace, C. R.; Subramanian, C.; Pant, S.
10.1101/2021.09.16.460654 — biophysics — Posted on 2021-09-16
1885 Unlabeled salivary gland organoids have distinct Raman signatures following FGF2-induced proacinar cell differentiation
Tubbesing, K. E.; Moskwa, N.; Khoo, T. C.; Nelson, D. A.; Sharikova, A.; Larsen, M.; Khmaladze, A.
10.1101/2021.09.16.460651 — biophysics — Posted on 2021-09-16
1889 SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells
Wang, Y.; Yen, F. S.; Zhu, X. G.; Timson, R. C.; Weber, R.; Xing, C.; Liu, Y.; Allwein, B.; Luo, H.; Yeh, H.-W.; Heissel, S.; Unlu, G.; Gamazon, E. R.; Kharas, M. G.; Hite, R.; Birsoy, K.
10.1101/2021.09.15.460381 — biochemistry — Posted on 2021-09-16
1890 Isolation and characterization of a highly specific monoclonal antibody targeting the botulinum neurotoxin type E exposed SNAP-25 neoepitope
Mechaly, A.; Diamant, E.; Alcalay, R.; Ben-David, A.; Dor, E.; Torgeman, A.; Barnea, A.; Girshengorn, M.; Levin, L.; Epstein, E.; Tennenhouse, A.; Fleishman, s.; Zichel, R.; Mazor, O.
10.1101/2021.09.16.460610 — biochemistry — Posted on 2021-09-16
1894 Modelling spatiotemporal trends in the frequency of genetic mutations conferring insecticide target-site resistance in African malaria vector species
Hancock, P. A.; Lynd, A.; Wiebe, A.; Devine, M.; Essandoh, J.; Wat'senga, F.; Manzambi, E. Z.; Agossa, F.; Donnelly, M. J.; Weetman, D. J.; Moyes, C. L.
10.1101/2021.09.15.460499 — genetics — Posted on 2021-09-16
1895 Predicting base editing outcomes using position-specific sequence determinants
Pallaseni, A.; Peets, E. M.; Koeppel, J.; Weller, J.; Crepaldi, L.; Allen, F.; Parts, L.
10.1101/2021.09.16.460622 — genetics — Posted on 2021-09-16
1902 Reticular Dysgenesis-associated Adenylate Kinase 2 deficiency causes failure of myelopoiesis through disordered purine metabolism
Wang, W.; DeVilbiss, A.; Arreola, M.; Mathews, T.; Martin-Sandoval, M.; Zhao, Z.; Awani, A.; Dever, D.; Al-Herz, W.; Noratangelo, L.; Porteus, M. H.; Morrison, S. J.; Weinacht, K. G.
10.1101/2021.07.05.450633 — cell biology — Posted on 2021-09-16
1904 MyD88 Mediates Colitis- and RANKL-induced Microfold Cell Differentiation
Li, Y.; Yang, S.; Huang, X.; Yang, N.; Wang, C.; Zhao, J.; Jing, Z.; Willems, L.; Liu, G.
10.1101/2021.09.16.460646 — cell biology — Posted on 2021-09-16
1907 A gut microbial metabolite of dietary polyphenols reverses obesity-driven hepatic steatosis
Osborn, L. J.; Schultz, K.; Massey, W.; DeLucia, B.; Choucair, I.; Varadharajan, V.; Fung, K.; Horak, A. J.; Orabi, D.; Nemet, I.; Nagy, L. E.; Wang, Z.; Allende, D. S.; Sangwan, N.; Hajjar, A. M.; McDonald, C.; Ahern, P. P.; Hazen, S. L.; Brown, J. M.; Claesen, J.
10.1101/2021.09.16.460661 — microbiology — Posted on 2021-09-16
1911 Zika Virus Infection of Murine and Human Neutrophils and their Function as Trojan Horses to the Placenta
Zanluqui, N. G.; Oliveira, L. G.; Polonio, C. M.; Franca, T. T.; Fabiano, G. S.; Muraro, S. P.; Amorim, M. R.; Carregari, V. C.; Brandao-Teles, C.; da Silva, P.; Oliveira, M. G.; Oliveira-Franca, R. F.; Cunha, M. P.; Nogueira, M.; Souza, D. M.; Condino-Neto, A.; Proenca-Modena, J. L.; Peron, J. P. S.
10.1101/2021.09.14.460378 — immunology — Posted on 2021-09-16
1912 Conserved induction of distinct antiviral signalling kinetics by primate interferon lambda 4 proteins
Guo, C.; Reuss, D.; Coey, J. D.; Sukumar, S.; Lang, B.; McLauchlan, J.; Boulant, S.; Stanifer, M. L.; Bamford, C.
10.1101/2021.09.15.460494 — immunology — Posted on 2021-09-16
1913 Neutralizing antibody-independent immunity to SARS-CoV-2 in hamsters and hACE-2 transgenic mice immunized with a RBD/Nucleocapsid fusion protein
Castro, J.; Fumagalli, M.; Hojo-Souza, N.; Azevedo, P.; Salazar, N.; Rattis, B.; Ramos, S.; Faustino, L.; Almeida, G.; Oliveira, L.; Marcal, T.; Augusto, M.; Magalhaes, R. D. M.; Cassaro, B.; Burle, G.; Doro, D.; Kalil, J.; Durigon, E. L.; Salazar, A.; Caballero, O.; Machado, A.; da Silva, J.; da Fonseca, F.; Fernandes, A. P.; Teixeira, S.; Gazzinelli, R.
10.1101/2021.09.16.460663 — immunology — Posted on 2021-09-16
1914 Recombinant NAGLU-IGF2 prevents physical and neurological disease and improves survival in Sanfilippo B syndrome
Le, S. Q.; Kan, S.-h.; Nunez, M.; Dearborn, J. T.; Wang, F.; LI, S.; Snella, L.; Jens, J. K.; Valentine, B. N.; Nelvagal, H. R.; Sorensen, A.; Cooper, J. D.; Chou, T.-F.; Ellinwood, N. M.; Smith, J. D.; Sands, M. S.; Dickson, P.
10.1101/2021.08.06.455469 — neuroscience — Posted on 2021-09-16
1919 Emergent myxobacterial behaviors arise from reversal suppression induced by kin contacts
Balagam, R.; Cao, P.; Sah, G. P.; Zhang, Z. A.; Subedi, K.; Wall, D.; Igoshin, O. A.
10.1101/2021.04.08.439045 — biophysics — Posted on 2021-09-16
1920 Single residue substitution in protamine 1 disrupts sperm genome packaging and embryonic development in mice
Moritz, L.; Schon, S.; Rabbani, M.; Sheng, Y.; Pendlebury, D.; Agrawal, R.; Sultan, C.; Jorgensen, K.; Zheng, X.; Diehl, A.; Ragunathan, K.; Hu, Y.-C.; Nandakumar, J.; Li, J.; Orwig, K.; Redding, S.; Hammoud, S.
10.1101/2021.09.16.460631 — biochemistry — Posted on 2021-09-16
1924 Tomato Prosystemin is much more than a simple Systemin precursor
Molisso, D.; Coppola, M.; Buonanno, M.; Di Lelio, I.; Monti, S. M.; Melchiorre, C.; Amoresano, A.; Corrado, G.; Frier, J. P. D.; Becchimanzi, A.; Pennacchio, F.; Rao, R.
10.1101/2021.09.15.460427 — genetics — Posted on 2021-09-16
1925 Uterus-specific transcriptional regulation underlies eggshell pigment production in Japanese quail
Ishishita, S.; Kitahara, S.; Takahashi, M.; Iwasaki, S.; Tatsumoto, S.; Hara, I.; Kaneko, Y.; Kinoshita, K.; Yamaguchi, K.; Harada, A.; Ohmori, Y.; Ohkawa, Y.; Go, Y.; Shigenobu, S.; Matsuda, Y.; Suzuki, T.
10.1101/2021.09.15.460419 — genetics — Posted on 2021-09-16
1928 An outbreak of Rift Valley fever among peri-urban dairy cattle in northern Tanzania, 2018
de Glanville, W. A.; Allan, K. J.; Nyarobi, J. M.; Thomas, K. M.; Lankester, F.; Kibona, T.; Claxton, J. R.; Brennan, B.; Carter, R. W.; Crump, J. A.; Halliday, J. E. B.; Ladbury, G.; Mmbaga, B. T.; Mramba, F.; Nyasebwa, O. M.; Rubach, M. P.; Rostal, M. K.; Sanka, P.; Swai, E. S.; Szemiel, A. M.; Willett, B. J.; Cleaveland, S.
10.1101/2021.09.15.459147 — ecology — Posted on 2021-09-16
1931 Critical roles of ICOS in controlling Foxp3-expressing T follicular cell subsets during early-stage germinal center reactions
Panneton, V.; Mindt, B. C.; Bouklouch, Y.; Chang, J.; Witalis, M.; Li, J.; Stancescu, A.; Bouchard, A.; Bradley, J. E.; Randall, T. D.; Fritz, J. H.; Suh, W.-K.
10.1101/2021.09.14.460384 — immunology — Posted on 2021-09-16
1932 NLRP3 activation in response to disrupted endocytic traffic
Lee, B.; Hoyle, C.; Green, J.; Wellens, R.; Martin-Sanchez, F.; Williams, D.; Seoane, P.; Bennett, H.; Adamson, A. D.; Lopez-Castejon, G.; Lowe, M.; Brough, D.
10.1101/2021.09.15.460426 — immunology — Posted on 2021-09-16
1934 5-HT2C agonists and antagonists block different components of behavioral responses to potential, distal, and proximal threat in zebrafish
do Carmo Silva, R. X.; do Nascimento, B. G.; Gomes, G. C. V.; Holanda da Silva, N. A.; Pinheiro, J. S.; da Silva Chaves, S. N.; Pimentel, A. F. N.; Costa, B. P. D.; Herculano, A. M.; Lima-Maximino, M.; Maximino, C.
10.1101/2020.10.04.324202 — neuroscience — Posted on 2021-09-16
1936 Analysis of Rod/Cone Gap Junctions from the Reconstruction of Mouse Photoreceptor Terminals
Ishibashi, M.; Keung, J.; Morgans, C. W.; Aicher, S.; Carroll, J.; Singer, J. H.; Jia, L.; Li, W.; Fahrenfort, I.; Ribelayga, C.; Massey, S.
10.1101/2021.09.06.459091 — neuroscience — Posted on 2021-09-16
1940 Humoral immune responses against seasonal coronaviruses predict efficiency of SARS-CoV-2 spike targeting, FcγR activation, and corresponding COVID-19 disease severity
Garrido, J. J.; Medina, M.; Bravo, F.; McGee, S.; Fuentes, F.; Calvo, M.; Bowman, J. W.; Bahl, C. D.; Barria, M. I.; Brachman, R. A.; Alvarez, R. A.
10.1101/2021.09.14.460338 — microbiology — Posted on 2021-09-16
1941 Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin
Osipiuk, J.; Wydorski, P. M.; Lanham, B. T.; Tesar, C.; Endres, M.; Engle, E.; Jedrzejczak, R.; Mullapudi, V.; Michalska, K.; Fidelis, K.; Fushman, D.; Joachimiak, A.; Joachimiak, L. A.
10.1101/2021.09.15.460543 — biophysics — Posted on 2021-09-16
1943 Mitochondrial translation occurs preferentially in the peri-nuclear mitochondrial network of cultured human cells.
Albus, C.; Berlinguer-Palmini, R.; Hewison, C.; McFarlane, F.; Savu, E.-A.; Lightowlers, R.; Chrzanowska-Lightowlers, Z.; Zorkau, M.
10.1101/2021.09.15.460460 — cell biology — Posted on 2021-09-16
1945 E3 ligase TRIM47 positively regulates endothelial activation and pulmonary inflammation through potentiating the K63-linked ubiquitination
Qian, Y.; Wang, Z.; Lin, H.; Lei, T.; Zhou, Z.; Huang, W.; Wu, X.; Zuo, L.; Wu, J.; Liu, Y.; Wang, L.-F.; Guan, X.-H.; Deng, K.-Y.; Fu, M.; Xin, H.-B.
10.1101/2021.09.15.460553 — cell biology — Posted on 2021-09-16
1946 Angiocrine IGFBP3 Spatially Coordinates IGF Signaling During Neonatal Cardiac Regeneration
Ali, S.; Elhelaly, W.; Nguyen, N. U. N.; Li, S.; Menendez-Montes, I.; Wang, Z.; Cui, M.; Elnwasany, A.; Xiao, F.; Thet, S.; Lam, N.; Cardoso, A.; Pereira, A. H.; Goodarzi, M.; Kinter, M.; Lemoff, A.; Szweda, L.; Shelton, J.; Kimura, W.; Sadek, H.
10.1101/2021.09.16.460522 — cell biology — Posted on 2021-09-16
1948 The ARF GAPs ELMOD1 and ELMOD3 act at the Golgi and Cilia to Regulate Ciliogenesis and Ciliary Protein Traffic
Turn, R. E.; Hu, Y.; Dewees, S. I.; Devi, N.; East, M. P.; Hardin, K. R.; Khatib, T.; Linnert, J.; Wolfrum, U.; Lim, J. Y.; Casanova, J. E.; Caspary, T.; Kahn, R. A.
10.1101/2021.09.15.460558 — cell biology — Posted on 2021-09-16
1949 Helical metaphase chromatid coiling is conserved
Kubalova, I.; Camara, A. S.; Capal, P.; Beseda, T.; Rouillard, J.-M.; Krause, G. M.; Toegelova, H.; Himmelbach, A.; Stein, N.; Houben, A.; Dolezel, J.; Mascher, M.; Simkova, H.; Schubert, V.
10.1101/2021.09.16.460607 — cell biology — Posted on 2021-09-16
1951 Hypoxia promotes a perinatal-like progenitor state in the adult murine epicardium
Sayed, A.; Turoczi, S.; Soares-da-Silva, F.; Marazzi, G.; Hulot, J.-S.; Sassoon, D. D. A.; Valente, M.
10.1101/2021.09.16.460580 — cell biology — Posted on 2021-09-16
1952 MICAL1 activation by PAK1 mediates actin filament disassembly
McGarry, D. J.; Castino, G.; Lilla, S.; Zanivan, S.; Olson, M. F.
10.1101/2021.09.15.460490 — cell biology — Posted on 2021-09-16
1954 PL1 Peptide Engages Acidic Surfaces on Tumor-Associated Fibronectin and Tenascin Isoforms to Trigger Cellular Uptake.
Lingasamy, P.; Posnograjeva, K.; Kopantsuk, S.; Tobi, A.; Rinken, A.; General, I. J.; Asciutto, E.; Teesalu, T.
10.1101/2021.09.16.460582 — cancer biology — Posted on 2021-09-16
1955 VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis
Watson, S.; LaVigne, C.; Xu, L.; Murchison, W.; Surdez, D.; Rakheja, D.; Tirode, F.; Delattre, O.; Amatruda, J.; Kendall, G. C.
10.1101/2021.09.15.460544 — cancer biology — Posted on 2021-09-16
1956 Gram-negative bacterial infection increases lung cancer metastasis via Toll-like receptor 1 activation and increased cancer cell proliferation post-tumor adhesion
Rayes, R. F.; Wilson, M. G.; Gowing, S. D.; Bourdeau, F.; Giannias, B.; Camilleri-Broet, S.; Fiset, P.-O.; Najmeh, S.; Spicer, J. D.; Ferri, L. E.; Cools-Lartigue, J.
10.1101/2021.09.15.460508 — cancer biology — Posted on 2021-09-16
1959 Impaired photoprotection in Phaeodactylum tricornutum KEA3 mutants reveals the proton regulatory circuit of diatoms light acclimation.
Seydoux, C.; Storti, M.; Giovagnetti, V.; Matuszynska, A.; Guglielmino, E.; Zhao, X.; Giustini, C.; Pan, Y.; Angulo, J.; Ruban, A. V.; Hu, H.; Bailleul, B.; Courtois, F.; Allorent, G.; Finazzi, G.
10.1101/2021.09.06.459119 — plant biology — Posted on 2021-09-16
1962 A genetic trap in yeast for inhibitors of SARS-CoV-2 main protease
Alalam, H.; Sigurdardottir, S.; Bourgard, C.; Tiukova, I. A.; King, R. D.; Grötli, M.; Sunnerhagen, P.
10.1101/2021.09.14.460411 — synthetic biology — Posted on 2021-09-16
1963 Addition of a carboxy terminal tail to the normally tailless gonadotropin-releasing hormone receptor impairs fertility in female mice
Toufaily, C.; Fortin, J.; Alonso, C. A. I.; Lapointe, E.; Zhou, X.; Santiago-Andres, Y.; Lin, Y.-F.; Cui, Y.; Wang, Y.; Devost, D.; Roelfsema, F.; Steyn, F.; Hanyaloglu, A. C.; Hebert, T.; Fiordelisio, T.; Boerboom, D.; Bernard, D. J.
10.1101/2021.09.13.460073 — physiology — Posted on 2021-09-16
1964 A G-protein-biased S1P1 agonist, SAR247799, improved LVH and diastolic function in a rat model of metabolic syndrome
Evaristi, M. F.; Poirier, B.; Chenede, X.; Lefebvre, A.-M.; Roccon, A.; Gillot, F.; Beskee, S.; Corbier, A.; Pruniaux-Harnist, M.-P.; Janiak, P.; Parkar, A.
10.1101/2021.09.14.460397 — pharmacology and toxicology — Posted on 2021-09-16
1965 Dinosaur bonebed amber from an original swamp forest soil
Alvarez-Parra, S.; Perez-de la Fuente, R.; Penalver, E.; Barron, E.; Alcala, L.; Perez-Cano, J.; Martin-Closas, C.; Trabelsi, K.; Melendez, N.; Lopez Del Valle, R.; Lozano, R. P.; Peris, D.; Rodrigo, A.; Sarto i Monteys, V.; Bueno-Cebollada, C. A.; Menor-Salvan, C.; Philippe, M.; Sanchez-Garcia, A.; Pena-Kairath, C.; Arillo, A.; Espilez, E.; Mampel, L.; Delclos, X.
10.1101/2021.09.14.460215 — paleontology — Posted on 2021-09-16
1966 Refractive-index matching enhanced polarization-sensitive optical coherence tomography quantification in human brain tissue
Liu, C. J.; Ammon, W.; Jones, R.; Nolan, J.; Wang, R.; Chang, S.; Frosh, M. P.; Yendiki, A.; Boas, D. A.; Magnain, C.; Fischl, B.; Wang, H.
10.1101/2021.09.12.459943 — bioengineering — Posted on 2021-09-16
1967 Ancient genomes redate the extinction of Sussemionus, a subgenus of Equus, to late Holocene
Cai, D.; Zhu, S.; Gong, M.; Zhang, N.; Wen, J.; Liang, Q.; Sun, W.; Shao, X.; Guo, Y.; Cai, Y.; Zheng, Z.; Zhang, W.; Hu, S.; Wang, X.; Tian, H.; Li, Y.; Liu, W.; Yang, M.; Yang, J.; Wu, D.; Orlando, L.; Jiang, Y.
10.1101/2021.09.13.460072 — genomics — Posted on 2021-09-16
1968 Little hope for the polyploid endemic Pyrenean Larkspur (Delphinium montanum): evidences from population genomics and Ecological Niche Modelling
Salvado, P.; Aymerich Boixader, P.; Parera, J.; Vila Bonfill, A.; Martin, M.; Quelennec, C.; Lewin, J.-M.; Hinoux, V.; Bertrand, J. A. M.
10.1101/2021.09.15.460086 — evolutionary biology — Posted on 2021-09-16
1970 A root for massive crown-of-thorns starfish outbreaks in the Pacific Ocean
Satoh, N.; Yasuda, N.; Inoue, J.; Hall, M. R.; Nair, M. R.; Adjeround, M.; Fortes, M.; Nishida, M.; Tuivavalagi, N.; Ravago-Gotanco, R.; Forsman, Z.; Soliman,, T.; Koyanagi, R.; Hisata, K.; Motti, C.
10.1101/2021.09.13.460188 — ecology — Posted on 2021-09-16
1973 Antifungal activity of fibrate-based compounds and substituted pyrroles inhibiting the enzyme 3-hydroxy-methyl-glutaryl-CoA reductase of Candida glabrata (CgHMGR), and decreasing yeast viability and ergosterol synthesis
Villa-Tanaca, L.; Madrigal-Aguilar, D. A.; Gonzalez-Silva, A.; Rosales-Acosta, B.; Bautista-Crescencio, C.; Ortiz-Alvarez, J.; Sanchez-Navarrete, J.; Escalante, C.; Hernandez-Rodriguez, C.; Chamorro-Cevallos, G.; Tamariz, J.
10.1101/2021.09.14.460412 — microbiology — Posted on 2021-09-16
1975 A model of preferential pairing between epithelial and dendritic cells in thymic antigen transfer
Filipp, D.; Blumberg, R. S.; Voboril, M.; Brezina, J.; Brabec, T.; Dobes, J.; Ballek, O.; Manning, J.; Dobesova, M.
10.1101/2021.09.13.460045 — immunology — Posted on 2021-09-16
1979 Whole-genome sequencing analysis reveals the population history of Mus musculus in Madagascar
Fujiwara, K.; Ranorosoa, M. C.; Ohdachi, S. D.; Arai, S.; Sakuma, Y.; Suzuki, H.; Osada, N.
10.1101/2021.09.10.459745 — genetics — Posted on 2021-09-16
1980 The genetic basis of tail-loss evolution in humans and apes
Xia, B.; Zhang, W.; Wudzinska, A.; Huang, E.; Brosh, R.; Pour, M.; Miller, A.; Dasen, J. S.; Maurano, M. T.; Kim, S. Y.; Boeke, J. D.; Yanai, I.
10.1101/2021.09.14.460388 — evolutionary biology — Posted on 2021-09-16
1986 Multivalent interactions facilitate motor-dependent protein accumulation at growing microtubule plus ends
Maan, R.; Reese, L.; Volkov, V. A.; King, M. R.; van der Sluis, E.; Andrea, N.; Evers, W.; Jakobi, A. J.; Dogterom, M.
10.1101/2021.09.14.460284 — cell biology — Posted on 2021-09-16
1987 Modeling miRNA-driven post-transcriptional regulation by using exon-intron split analysis (EISA) in pigs
Marmol-Sanchez, E.; Cirera, S.; Zingaretti, L.; Jacobsen, M. J.; Ramayo-Caldas, Y.; Jorgensen, C. B.; Fredholm, M.; Cardoso, T. F.; Quintanilla, R.; Amills, M.
10.1101/2021.07.14.452370 — genomics — Posted on 2021-09-16
1991 Conformation of HIV-1 Envelope governs rhesus CD4 usage and simian-human immunodeficiency virus replication
Vilmen, G.; Smith, A. C.; Benet, H. C.; Shukla, R. K.; Larue, R. C.; Herschhorn, A.; Sharma, A.
10.1101/2021.08.25.457697 — microbiology — Posted on 2021-09-16
1992 Reward enhances memory via age-varying online and offline neural mechanisms across development
Cohen, A. O.; Glover, M. M.; Shen, X.; Phaneuf, C. V.; Avallone, K. N.; Davachi, L.; Hartley, C. A.
10.1101/2021.09.14.460286 — neuroscience — Posted on 2021-09-16
1994 Large-scale neural recordings with single-cell resolution in human cortex using high-density Neuropixels probes
Paulk, A. C.; Kfir, Y.; Khanna, A.; Mustroph, M.; Trautmann, E. M.; Soper, D. J.; Stavisky, S. D.; Welkenhuysen, M.; Dutta, B.; Shenoy, K. V.; Hochberg, L. R.; Richardson, M.; Williams, Z. M.; Cash, S. S.
10.1101/2021.06.20.449152 — neuroscience — Posted on 2021-09-16
1996 Mutations in Auxilin cause parkinsonism via impaired clathrin-mediated trafficking at the Golgi apparatus and synapse
Roosen, D. A.; Landeck, N.; Bonet-Ponce, L.; Kluss, J.; Conti, M.; Smith, N.; Saez-Atienzar, S.; Ding, J.; Beilina, A.; Kumaran, R.; Kaganovich, A.; du Hoffmann, J.; Williamson, C.; Gershlick, D. C.; Sampieri, L.; Bleck, C. K. E.; Liu, C.; Bonifacino, J. S.; Li, Y.; Lewis, P. A.; Cookson, M. R.
10.1101/830802 — neuroscience — Posted on 2021-09-16
1997 Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson's disease
Lin, Y.-E.; Lin, C.-H.; Ho, E.-P.; Ke, Y.-C.; Petridi, S.; Elliott, C. J. H.; Sheen, L.-Y.; Chien, C.-T.
10.1101/2021.08.25.457612 — neuroscience — Posted on 2021-09-16
2000 Muscle weakness precedes atrophy during cancer cachexia and is associated with muscle-specific mitochondrial stress
Delfinis, L. J.; Bellissimo, C. A.; Gandhi, S.; DiBenedetto, S. N.; Rosa-Caldwell, M. E.; Rahman, F. A.; Wiggs, M. P.; Schlattner, U.; Quadrilatero, J.; Greene, N. P.; Perry, C. G. R.
10.1101/2021.09.15.460477 — physiology — Posted on 2021-09-16
2001 Identification of a discrete neuronal circuit that relays insulin signaling into the brain to regulate glucose homeostasis
El Mehdi, M.; Takhlidjt, S.; Devere, M.; Arabo, A.; Le Solliec, M.-A.; Maucotel, J.; Benani, A.; Nedelec, E.; Duparc, C.; Lefranc, B.; Leprince, J.; Anouar, Y.; Prevost, G.; Chartrel, N.; PICOT, M.
10.1101/2021.09.13.460055 — physiology — Posted on 2021-09-16
2007 High-quality genome assembly of Cinnamomum burmami (chvar. Borneol) provides insights into the natural borneol biosynthesis
Li, F.; Huang, S.; Mei, Y.; Wu, B.; Hou, Z.; Zhan, P.; Cai, S.; Liu, Q.; Hou, Z.; Wang, J.; Zhao, J.
10.1101/2021.09.14.460210 — genomics — Posted on 2021-09-16
2014 Defective endosome-TGN retrograde transport promotes NLRP3 inflammasome activation
ZHANG, Z.; RAN, L.; Venditti, R.; Liu, Z.; Schurmann, A.; Bonifacino, J. S.; De Matteis, M. A.; RICCI, R.
10.1101/2021.09.14.460331 — immunology — Posted on 2021-09-16
2015 Repertoire of naturally acquired maternal antibodies transferred to infants for protection against shigellosis
Ndungo, E.; Andronescu, L. R.; Buchwald, A. G.; Lemme-Dumit, J. M.; Mawindo, P.; Kapoor, N.; Fairman, J.; Laufer, M. K.; Pasetti, M. F.
10.1101/2021.05.21.445178 — immunology — Posted on 2021-09-16
2016 In lupus nephritis, specific in situ inflammatory states are associated with refractory disease and progression to renal failure
Abraham, R.; Durkee, M. S.; Ai, J.; Veselits, M.; Casella, G.; Asano, Y.; Chang, A.; Ko, K.; Oshinsky, C.; Peninger, E.; Giger, M.; Clark, M. R.
10.1101/2021.09.03.458909 — immunology — Posted on 2021-09-16
2018 Gli1 regulates the postnatal acquisition of peripheral nerve architecture
Zotter, B. C.; Dagan, O.; Brady, J.; Baloui, H.; Samanta, J.; Salzer, J. L.
10.1101/2021.09.14.460314 — neuroscience — Posted on 2021-09-16
2019 Chronic sodium bromide treatment relieves autistic-like behavioral deficits in three mouse models of autism
Derieux, C.; Leaute, A.; Brugoux, A.; Jaccaz, D.; Pin, J.-P.; Kniazeff, J.; Le Merrer, J.; Becker, J. A.
10.1101/2021.09.14.460257 — neuroscience — Posted on 2021-09-16
2020 The calcium sensor synaptotagmin-1 is critical for phasic axonal dopamine release in the striatum and mesencephalon, but is dispensable for basic motor behaviors in mice
Delignat-Lavaud, B.; Kano, J.; Ducrot, C.; Masse, I.; Mukherjee, S.; Giguere, N.; Moquin, L.; Levesque, C.; Nanni, S. B.; Bourque, M.-J.; Rosa-Neto, P.; Levesque, D.; De Beaumont, L.; Trudeau, L.-E.
10.1101/2021.09.15.460511 — neuroscience — Posted on 2021-09-16
2021 Disruption of the autism-associated gene SCN2A alters synaptic development and neuronal signaling in patient iPSC-glutamatergic neurons
Brown, C. O.; Uy, J.; Murtaza, N.; Rosa, E.; Afonso, A.; Xing, S.; Dave, B. M.; Kilpatrick, S.; Cheng, A. A.; White, S. H.; Howe, J.; Scherer, S. W.; Lu, Y.; Singh, K. K.
10.1101/2021.09.14.460368 — neuroscience — Posted on 2021-09-16
2023 Substrate specialization in microbes is driven by biochemical constraints of dynamic flux sensing
Schink, S. J.; Christodoulou, D.; Mukherjee, A.; Athaide, E.; Brunner, V.; Fuhrer, T.; Bradshaw, G. A.; Sauer, U.; Basan, M.
10.1101/2021.05.07.443112 — systems biology — Posted on 2021-09-15
2025 Four layer multi-omics reveals molecular responses to aneuploidy in Leishmania
Cuypers, B.; Meysman, P.; Erb, I.; Bittremieux, W.; Valkenborg, D.; Baggerman, G.; Mertens, I.; Sundar, S.; Khanal, B.; Notredame, C.; Dujardin, J.-C.; Domagalska, M. A.; Laukens, K.
10.1101/2021.09.14.460245 — systems biology — Posted on 2021-09-15
2026 Dry heat sterilization as a method to recycle N95 respirator masks: the importance of fit
Yuen, J. G.; Marschilok, A. C.; Benziger, P. T.; Yan, S.; Cello, J.; Stackhouse, C. A.; Kisslinger, K.; Bock, D. C.; Takeuchi, E. S.; Takeuchi, K. J.; Wang, L.; Babu, S.; Itzkowitz, G.; Thanassi, D.; Knopf, D.; Shroyer, K.
10.1101/2021.09.15.460526 — scientific communication and education — Posted on 2021-09-15
2027 Compounds enhancing human sperm motility identified using a high-throughput phenotypic screening platform
Gruber, F. S.; Johnston, Z. C.; Norcross, N. R.; Georgiou, I.; Wilson, C.; Read, K. D.; Gilbert, I. H.; Swedlow, J. R.; Martins de Silva, S.; Barratt, C. L.
10.1101/2021.09.14.460292 — physiology — Posted on 2021-09-16
2030 Aberrant epigenetic and transcriptional events associated with breast cancer risk
Marino, N.; German, R.; Podicheti, R.; Rusch, D. B.; Rockey, P.; Huang, J.; Sandusky, G. E.; Temm, C. J.; Althouse, S. K.; Nephew, K. P.; Nakshatri, H.; Liu, J.; Vode, A.; Cao, S.; Storniolo, A. M.
10.1101/2021.09.14.460320 — cancer biology — Posted on 2021-09-15
2031 Molecular Drivers of Tumor Progression in Microsatellite Stable APC Mutation-Negative Colorectal Cancers
Grant, A.; Xicola, R. M.; Nguyen, V. T.; Lim, J.; Thorne, C.; Salhia, B.; Llor, X.; Ellis, N.; Padi, M.
10.1101/2021.09.14.460319 — cancer biology — Posted on 2021-09-16
2037 Proximal CA3 is the primary locus of age-related pattern separation deficits in rats
Lee, H.; Tilekeratne, A.; Lukish, N.; Wang, Z.; Zeger, S.; Gallagher, M.; Knierim, J. J.
10.1101/2021.09.14.460329 — animal behavior and cognition — Posted on 2021-09-16
2038 Haplotype-aware inference of human chromosome abnormalities
Ariad, D.; Yan, S. M.; Victor, A. R.; Barnes, F. L.; Zouves, C. G.; Viotti, M.; McCoy, R. C.
10.1101/2021.05.18.444721 — genomics — Posted on 2021-09-15
2042 Integrated gene analyses of de novo mutations from 46,612 trios with autism and developmental disorders
Wang, T.; Kim, C.; Bakken, T. E.; Gillentine, M. A.; Henning, B.; Mao, Y.; Gilissen, C.; Consortium, S.; Nowakowski, T. J.; Eichler, E. E.
10.1101/2021.09.15.460398 — genetics — Posted on 2021-09-16
2043 Life-history genotype explains variation in migration activity in Atlantic salmon (Salmo salar).
Niemela, P. T.; Klemme, I.; Karvonen, A.; Hyvarinen, P.; Debes, P. V.; Erkinaro, J.; Sinclair-Waters, M.; Pritchard, V. L.; Harkonen, L.; Primmer, C. R.
10.1101/2021.09.14.460042 — evolutionary biology — Posted on 2021-09-15
2044 The secrets to domestic bliss - Partner fidelity and environmental filtering preserve stage-specific turtle ant gut symbioses for over 40 million years
Hu, Y.; D'Amelio, C. L.; Bechade, B.; Cabuslay, C. S.; Sanders, J. G.; Price, S.; Fanwick, E.; Powell, S.; Moreau, C.; Russell, J. A.
10.1101/2021.09.13.460005 — evolutionary biology — Posted on 2021-09-16
2046 Piperacillin/tazobactam resistant, cephalosporin susceptible Escherichia coli bloodstream infections are driven by multiple acquisition of resistance across diverse sequence types
Edwards, T.; Heinz, E.; van Aartsen, J.; Howard, A.; Roberts, P.; Corless, C.; Fraser, A. J.; Williams, C. T.; Bulgasim, I.; Cuevas, L. E.; Parry, C. M.; Roberts, A. P.; Adams, E. R.; Mason, J.; Hubbard, A.
10.1101/2020.09.18.302992 — microbiology — Posted on 2021-09-15
2049 The role of antigen recognition in the γδ T cell response at the controlled stage of M. tuberculosis infection.
Roy Chowdhury, R.; Valainis, J. R.; Kask, O.; Ohanyan, M.; Sun, M.; Huang, H.; Dubey, M.; von Boehmer, L.; Sola, E.; Huang, X.; Nguyen, P. K.; Scriba, T.; Davis, M. M.; Bendall, S. C.; Chien, Y.-h.
10.1101/2021.09.14.460324 — immunology — Posted on 2021-09-15
2051 Visualizing synaptic plasticity in vivo by large-scale imaging of endogenous AMPA receptors
Graves, A. R.; Roth, R.; Tan, H.; Zhu, Q.; Bygrave, A.; Lopez-Ortega, E.; Spiegel, A.; Hong, I.; Johnson, R.; Vogelstein, J.; Tward, D.; Miller, M.; Huganir, R. L.
10.1101/2020.03.01.972216 — neuroscience — Posted on 2021-09-15
2054 The individuality of shape asymmetries of the human cerebral cortex
Chen, Y.-C.; Arnatkeviciute, A.; McTavish, E.; Pang, J.; Suo, C.; Fornito, A.; Aquino, K. M.; The Alzheimer's Disease Neuroimaging Initiative,
10.1101/2021.09.14.460242 — neuroscience — Posted on 2021-09-15
2059 Movement decoding using spatio-spectral features of cortical and subcortical local field potentials
Peterson, V.; Merk, T.; Bush, A.; Nikulin, V.; Kühn, A. A.; Neumann, W.-J.; Richardson, R. M.
10.1101/2021.06.06.447145 — neuroscience — Posted on 2021-09-15
2061 Environmental and molecular modulation of motor individuality in larval zebrafish
Hageter, J.; Waalkes, M.; Starkey, J.; Copeland, H.; Price, H.; Bays, L.; Showman, C.; Laverty, S.; Bergeron, S. A.; Horstick, E. J.
10.1101/2021.09.14.460248 — neuroscience — Posted on 2021-09-16
2063 XePhIR: The zebrafish Xenograft Phenotype Interactive Repository
Groenewoud, A.; Forn-Cuni, G.; Engel, F.; Snaar-Jagalska, E. B. E.
10.1101/2021.09.13.460043 — cancer biology — Posted on 2021-09-15
2064 RUNIMC: An R-based package for imaging mass cytometry data analysis and pipeline validation
Dolcetti, L.; Barber, P. R.; Weitsman, G.; Thavaraj, S.; Ng, K.; Chan, J. N. E.; Patten, P.; Mustapha, R.; Deng, J.; Ng, T.
10.1101/2021.09.14.460258 — cancer biology — Posted on 2021-09-15
2065 Influenza A M2 Channel Oligomerization is Sensitive to its Chemical Environment
Townsend, J. A.; Sanders, H. M.; Rolland, A. D.; Park, C.; Horton, N.; Prell, J. S.; Wang, J.; Marty, M. T.
10.1101/2021.05.07.443160 — biophysics — Posted on 2021-09-15
2071 Novel genotyping algorithms for rare variants significantly improve the accuracy of Applied Biosystems™ Axiom™ array genotyping calls
Mizrahi Man, O.; Woehrmann, M. H.; Webster, T. A.; Gollub, J.; Bivol, A.; Keeble, S. M.; Aull, K. H.; Mittal, A.; Roter, A. H.; Wong, B. A.; Schmidt, J. P.
10.1101/2021.09.13.459984 — genetics — Posted on 2021-09-15
2074 RevGadgets: an R Package for visualizing Bayesian phylogenetic analyses from RevBayes
Tribble, C. M.; Freyman, W. A.; Lim, J. Y.; Landis, M. J.; Barido-Sottani, J.; Kopperud, B. T.; Höhna, S.; May, M. R.
10.1101/2021.05.10.443470 — evolutionary biology — Posted on 2021-09-15
2075 Embracing imperfection: machine-assisted invertebrate classification in real-world datasets
Blair, J. D.; Weiser, M. D.; deBeurs, K.; Kaspari, M.; Siler, C. D.; Marshall, K. E.
10.1101/2021.09.13.460161 — ecology — Posted on 2021-09-15
2077 Performance of the sea turtle Lepidochelys olivacea hatchlings from a hatchery on the Pacific coast of Guatemala
Morales-Merida, B. A.; Contreras-Merida, M. R.; Cortes Gomez, A. A.; Godfrey, M. H.; Girondot, M.
10.1101/2021.09.13.460182 — ecology — Posted on 2021-09-15
2082 Impaired KDM2B-mediated PRC1 recruitment to chromatin causes neural stem cell senescence and ASD/ID-like behavioral deficits
Gao, Y.; Duque-Wilckens, N.; Aljazi, M. B.; Moeser, A. J.; Mias, G. I.; Robison, A. J.; Zhang, Y.; He, J.
10.1101/2021.09.13.459918 — neuroscience — Posted on 2021-09-15
2084 Social isolation is linked to classical risk factors of Alzheimer's disease-related dementias
Shafighi, K.; Villeneuve, S.; Rosa-Neto, P.; Badhwar, A.; Poirier, J.; Sharma, V.; Iturria-Medina, Y.; Silveira, P. P.; Dube, L.; Glahn, D.; Bzdok, D.
10.1101/2021.09.13.460121 — neuroscience — Posted on 2021-09-15
2087 Application of the Anatomical Fiducials Framework to a Clinical Dataset of Patients with Parkinsons Disease
Abbass, M.; Gilmore, G.; Taha, A.; Chevalier, R.; Jach, M.; Peters, T. M.; Khan, A. R.; Lau, J. C.
10.1101/2020.12.17.423333 — neuroscience — Posted on 2021-09-15
2088 Mapping brain-wide excitatory projectome of primate prefrontal cortex at submicron resolution: relevance to diffusion tractography
Yan, M.; Yu, W.; Lv, Q.; Lv, Q.; Bo, T.; Chen, X.; Liu, Y.; Zhan, Y.; Yan, S.; Shen, X.; Yang, B.; Qiu, Z.; Feng, Y.; Zhang, X.-Y.; Wang, H.; Xu, F.; Wang, Z.
10.1101/2021.09.13.460040 — neuroscience — Posted on 2021-09-15
2090 Synthetic amyloid beta does not induce a robust transcriptional response in innate immune cell culture systems
Quiroga, I. Y.; Cruikshank, A. E.; Reed, K. S. M.; Bond, M. L.; Evangelista, B. A.; Tseng, J.-H.; Ragusa, J. V.; Meeker, R. B.; Won, H.; Cohen, S.; Cohen, T. J.; Phanstiel, D. H.
10.1101/2021.09.14.460110 — neuroscience — Posted on 2021-09-15
2091 The role of superstition of cognitive control during neurofeedback training
Groessinger, D.; Fischmeister, F. P. S.; Witte, M.; Koschutnig, K.; Ninaus, M.; Neuper, C.; Kober, S.; Wood, G.
10.1101/2021.09.14.460252 — neuroscience — Posted on 2021-09-15
2092 Gonadal hormones and sex chromosome complement differentially contribute to ethanol intake, preference, and relapse-like behavior in Four Core Genotypes mice
Sneddon, E. A.; Rasizer, L. N.; Cavalco, N. G.; Jaymes, A. H.; Ostlie, N. J.; Minshall, B. L.; Masters, B. M.; Hrncir, H.; Arnold, A. P.; Radke, A. K.
10.1101/2021.04.28.441845 — neuroscience — Posted on 2021-09-15
2093 Brain kernel: a new spatial covariance function for fMRI data
Wu, A.; Nastase, S. A.; Baldassano, C. A.; Turk-Browne, N. B.; Norman, K. A.; Engelhardt, B. E.; Pillow, J. W.
10.1101/2021.03.22.436524 — neuroscience — Posted on 2021-09-15
2094 Adenylate kinase 1 overexpression increases locomotor activity in medaka fish
Maruyama, M.; Furukawa, Y.; Kinoshita, M.; Mukaiyama, A.; Akiyama, S.; Yoshimura, T.
10.1101/2021.09.15.460533 — physiology — Posted on 2021-09-15
2096 Morphometric Analysis of Lungfish Endocasts Elucidates Early Dipnoan Palaeoneurological Evolution
Clement, A. M.; Challands, T. J.; Cloutier, R.; Houle, L.; Ahlberg, P. E.; Collin, S. P.; Long, J. A.
10.1101/2021.09.13.460037 — paleontology — Posted on 2021-09-15
2101 Development of an in-situ printing system with human platelet lysate based bioink to treat corneal perforation
You, J.; Frazer, H.; Sayyar, S.; Chen, Z.; Liu, X.; Taylor, A.; Filippi, B.; Wise, I.; Hodge, C.; Wallace, G.; Sutton, G.
10.1101/2021.09.13.460167 — bioengineering — Posted on 2021-09-15
2102 The Effects of Incline Level on Optimized Lower-Limb Exoskeleton Assistance
Franks, P. W.; Bryan, G. M.; Reyes, R.; O'Donovan, M. P.; Gregorczyk, K. N.; Collins, S. H.
10.1101/2021.09.13.460170 — bioengineering — Posted on 2021-09-15
2104 Behavior in mice subjected to a Token Slot-machine: effect of Unpredictable Chronic Mild Stress
Sfregola, A. E.; Brizard, B.; Le Guisquet, A.-M.; Tillet, C.; Lefevre, E.; Bruni, L.; Belzung, C.
10.1101/2021.09.12.459992 — animal behavior and cognition — Posted on 2021-09-15
2108 Planktonic protist diversity across contrasting Subtropical and Subantarctic waters of the southwest Pacific
Gutierrez-Rodriguez, A.; Lopes dos Santos, A.; Safi, K.; Probert, I.; Not, F.; Fernandez, D.; Gourvil, P.; Bilewitch, J.; Hulston, D.; Pinkerton, M.; Nodder, S. D.
10.1101/2021.09.12.459994 — ecology — Posted on 2021-09-15
2109 DNA metabarcoding reveals host-specific communities of arthropods residing in fungal fruit bodies
Maurice, S.; Kauserud, H.; Birkemoe, T.; Jacobsen, R.; Sverdrup-Thygeson, A.; Lunde, L.; Boddy, L.
10.1101/2021.09.13.460044 — ecology — Posted on 2021-09-15
2111 IPMK physically binds to the SWI/SNF complex and modulates BRG1 occupancy
Lee, D.; Beon, J.; Han, S.; Park, S. E.; Hyun, K.; Lee, S.-Y.; Rhee, H.-W.; Seo, J. K.; Kim, J.; Kim, S.
10.1101/2021.09.15.460446 — molecular biology — Posted on 2021-09-15
2112 Droplet-based Single-cell Total RNA-seq Reveals Differential Non-Coding Expression and Splicing Patterns during Mouse Development
Salmen, F.; De Jonghe, J.; Kaminski, T. S.; Alemany, A.; Parada, G.; Verity-Legg, J.; Yanagida, A.; Kohler, T. N.; Battich, N.; van den Brekel, F.; Ellermann, A. L.; Arias, A. M.; Nichols, J.; Hemberg, M.; Hollfelder, F.; van Oudenaarden, A.
10.1101/2021.09.15.460240 — molecular biology — Posted on 2021-09-15
2114 EROS-mediated control of NOX2 and P2X7 biosynthesis
Randzavola, L. O.; Mortimer, P. M.; Garside, E. C.; Dufficy, E. R.; Schejtman, A.; Roumelioti, G.; Yu, L.; Pardo, M.; Tolley, C.; Brandt, C.; Harcourt, K.; Nahorski, M.; Woods, G.; Williamson, J. C.; Suresh, S.; Sowerby, J. M.; Rae, W. M.; Lehner, P. J.; Chaudhary, J. S.; Clare, S.; Speak, A. O.; Santilli, G.; Magnani, F.; Smith, K. G. C.; Thomas, D. C.
10.1101/2021.09.14.460103 — immunology — Posted on 2021-09-15
2116 Insertive vaginal sex has a profound impact on the penile immune correlates of HIV susceptibility
Mohammadi, A.; Bagherichimeh, S.; Choi, Y.; Fazel, A.; Tevlin, E.; Huibner, S.; Shao, E.; Zuanazzi, D.; Prodger, J.; Good, S. V.; Tharao, W.; Kaul, R.
10.1101/2021.09.13.460019 — immunology — Posted on 2021-09-15
2117 Permutational immune analysis reveals architectural similarities between inflammaging, Down syndrome and autoimmunity
Lambert, K.; Moo, K. G.; Arnett, A.; Goel, G.; Flynn, K. J.; Speake, C.; Wiedeman, A. E.; Greenbaum, C. J.; Long, S. A.; Partridge, R.; Buckner, J. H.; Khor, B.
10.1101/2021.09.13.460115 — immunology — Posted on 2021-09-15
2119 Structural Disconnection of the Posterior Medial Frontal Cortex Reduces Speech Error Monitoring
McCall, J.; Dickens, J. V.; Mandal, A.; DeMarco, A. T.; Fama, M.; Lacey, E.; Kelkar, A.; Medaglia, J.; Turkeltaub, P.
10.1101/2021.09.13.460087 — neuroscience — Posted on 2021-09-15
2120 Adaptation and serial choice bias are unaltered in autism
Bosch, E.; Fritsche, M.; Utzerath, C.; Buitelaar, J. K.; de Lange, F. P.
10.1101/2021.09.13.460060 — neuroscience — Posted on 2021-09-15
2121 Blood-based untargeted metabolomics in Relapsing-Remitting Multiple Sclerosis revealed the testable therapeutic target
Zahoor, I.; Suhail, H.; Dutta, I.; Ahmed, M. E.; Poisson, L.; Waters, J.; Bin, R.; Singh, J.; Cerghet, M.; Kumar, A.; Hoda, N.; Rattan, R.; Mangalam, A. K.; Giri, s.
10.1101/2021.09.13.460085 — neuroscience — Posted on 2021-09-15
2122 Synthetic lethality-based prediction of anti-SARS-CoV-2 targets
Pal, L. R.; Cheng, K.; Nair, N. U.; Martin-Sancho, L.; Sinha, S.; Pu, Y.; Riva, L.; Yin, X.; Schischlik, F.; Lee, J. S.; Chanda, S. K.; Ruppin, E.
10.1101/2021.09.14.460408 — systems biology — Posted on 2021-09-15
2123 Network- and Enrichment-based Inference of Phenotypes and Targets from large-scale Disease Maps
Hoch, M.; Gupta, S. S.; Cesnulevicius, K.; Lescheid, D.; Schultz, M.; Wolkenhauer, O.; Gupta, S.
10.1101/2021.09.13.460023 — systems biology — Posted on 2021-09-15
2124 Identifying locations susceptible to micro-anatomical reentry using a spatial network representation of atrial fibre maps
Falkenberg, M.; Coleman, J. A.; Dobson, S.; Hickey, D. J.; Terrill, L.; Ciacci, A.; Thomas, B.; Peters, N. S.; Sau, A.; Ng, F. S.; Zhao, J.; Christensen, K.
10.1101/2021.09.13.460069 — physiology — Posted on 2021-09-15
2125 Dysregulation of the Tweak/Fn14 pathway in skeletal muscle of spinal muscular atrophy mice
Meijboom, K. E.; McFall, E.; Anthony, D.; Edwards, B.; Kubinski, S.; Hazell, G.; Ahlskog, N.; Claus, P.; Davies, K. E.; Wood, M.; Bowerman, M.
10.1101/2021.09.13.460053 — pathology — Posted on 2021-09-15
2128 MetaTrass: High-quality Metagenomic Taxonomic Read Assembly of Single-Species based on co-barcoding sequencing data and references
Qi, Y.; Gu, S.; Zhang, Y.; Guo, L.; Xu, M.; Cheng, X.; Wang, O.; Chen, J.; Fang, X.; Liu, X.; Deng, L.; Fan, G.
10.1101/2021.09.13.459686 — bioinformatics — Posted on 2021-09-15
2132 Intronization enhances expression of S-protein and other transgenes challenged by cryptic splicing
Tomberg, K.; Antunes, L.; Pan, Y.; Hepkema, J.; Garyfallos, D. A.; Mahfouz, A.; Bradley, A.
10.1101/2021.09.15.460454 — genetics — Posted on 2021-09-15
2134 Evaluation of microbiome enrichment and host DNA depletion in human vaginal samples using Oxford Nanopore's adaptive sequencing
Marquet, M.; Zoellkau, J.; Pastuschek, J.; Viehweger, A.; Schleussner, E.; Makarewicz, O.; Pletz, M. W.; Ehricht, R.; Brandt, C.
10.1101/2021.09.15.460450 — molecular biology — Posted on 2021-09-15
2135 Human - murine concordance of molecular signatures in nerve-sparing murine partial bladder outlet obstruction (NeMO)
Aitken, K. J.; Sidler, M.; Ahmed, A.; Jiang, J.-X.; Koshkebaghi, d.; Yadav, P.; Davani, D.; Huang, R.; Weksberg, R.; Bagli, D. J.
10.1101/2021.09.15.460523 — molecular biology — Posted on 2021-09-15
2136 Fast and reliable sgRNA efficiency testing using HIReff
Marks, D.; Anstatt, J.; Bachmann, L.; Villarejo, L. G.; Geidies, A.; Mueller, T.
10.1101/2021.09.15.460502 — molecular biology — Posted on 2021-09-15
2137 Dynamic behavior of cell-free mitochondrial DNA in human saliva
Trumpff, C.; Rausser, S.; Haahr, R.; Karan, K. R.; Gouspillou, G.; Kirschbaum, C.; Picard, M.
10.1101/2021.09.15.460321 — molecular biology — Posted on 2021-09-15
2139 Revealing spatio-temporal dynamics with long-term trypanosomatid live-cell imaging
Muniz, R. S.; Campbell, P. C.; Sladewski, T. E.; Renner, L. D.; de Graffenried, C. L.
10.1101/2021.09.15.460474 — microbiology — Posted on 2021-09-15
2140 Poly (acetyl arginyl) glucosamine attenuates Pseudomonas aeruginosa in a rat lung infection model
Garcia, B.; McDaniel, M. S.; Loughran, A. J.; Johns, J. D.; Narayanaswamy, V.; Petty, C. F.; Birket, S.; Baker, S.; Barnaby, R.; Stanton, B. A.; Foote, J.; Rowe, S.; Swords, W. E.
10.1101/2021.09.15.460521 — microbiology — Posted on 2021-09-15
2141 Characterization of the microbiota associated with 12-week-old bovine fetuses exposed to divergent in utero nutrition
Amat, S.; Holman, D. B.; Schmidt, K.; McCarthy, K. L.; Dorsam, S. T.; Ward, A. K.; Borowicz, P. P.; Reynolds, L. P.; Caton, J.; Sedivec, K. K.; Dahlen, C. R.
10.1101/2021.09.14.460234 — microbiology — Posted on 2021-09-15
2142 Identification of CRF66_BF, a new HIV-1 circulating recombinant form of South American origin
Bacque, J.; Delgado, E.; Benito, S.; Moreno-Lorenzo, M.; Montero, V.; Gil, H.; Sanchez, M.; Nieto-Toboso, M. C.; Munoz, J.; Zubero-Sulibarria, M. Z.; Ugalde, E.; Garcia-Bodas, E.; Canada, J. E.; del Romero, J.; Rodriguez, C.; Rodriguez-Avial, I.; Elorduy-Otazua, L.; Portu, J. J.; Garcia-Costa, J.; Ocampo, A.; Cabrera, J. J.; Thomson, M. M.
10.1101/2021.09.14.460288 — microbiology — Posted on 2021-09-15
2143 The conventional dendritic cell 1 subset primes CD8+ T cells and traffics tumor antigen to drive anti-tumor immunity in the brain
Bowman-Kirigin, J. A.; Saunders, B. T.; Desai, R.; Wang, A. Z.; Schaettler, M. O.; Liu, C. J.; Livingstone, A. J.; Kobayashi, D. K.; Durai, V.; Kretzer, N. M.; Zipfel, G. J.; Leuthardt, E. C.; Osbun, J. W.; Chicoine, M. R.; Kim, A. H.; Murphy, K. M.; Johanns, T. M.; Zinselmeyer, B. H.; Dunn, G. P.
10.1101/2021.09.13.460088 — immunology — Posted on 2021-09-15
2145 Molecular architecture of SARS-CoV-2 envelope by integrative modeling
Pezeshkian, W.; Grunewald, F.; Narykov, O.; Lu, S.; Wassenaar, T.; Marrink, S.-J. J.; Korkin, D.
10.1101/2021.09.15.459697 — biophysics — Posted on 2021-09-15
2146 Transitioning to confined spaces impacts bacterial swimming and escape response
Lynch, J. B.; James, N.; McFall-Ngai, M.; Ruby, E. G.; Shin, S.; Takagi, D.
10.1101/2021.09.15.460467 — biophysics — Posted on 2021-09-15
2147 Mechanism of broad-spectrum Cas9 inhibition by AcrIIA11
Dillard, K. E.; Terrace, C.; Javanmardi, K.; Kim, W.; Forsberg, K. J.; Finkelstein, I. J.
10.1101/2021.09.15.460536 — biophysics — Posted on 2021-09-15
2149 Minos: variant adjudication and joint genotyping of cohorts of bacterial genomes
Hunt, M.; Letcher, B.; Malone, K. M.; Nguyen, G.; Hall, M. B.; Colquhoun, R. M.; Lima, L.; Schatz, M.; Ramakrishnan, S.; The CRyPTIC Consortium, ; Iqbal, Z.
10.1101/2021.09.15.460475 — bioinformatics — Posted on 2021-09-15
2155 Examining Batch Effect in Histopathology as a Distributionally Robust Optimization Problem
Hari, S. N.; Nyman, J.; Mehta, N.; Jiang, B.; Rosenthal, J.; Sengupta, E.; Dietlein, F.; Umeton, R.; Van Allen, E. M.
10.1101/2021.09.14.460365 — cancer biology — Posted on 2021-09-15
2157 Transcutaneous auricular vagus nerve stimulation increases eye-gaze on salient facial features and oxytocin release
Zhu, S.; Qing, Y.; Zhang, Y.; Zhang, X.; Ding, F.; Zhang, R.; Yao, S.; Kendrick, K. M.; Zhao, W.
10.1101/2021.09.12.459983 — neuroscience — Posted on 2021-09-15
2160 Non-linear functional brain co-activations in short-term memory distortion tasks
Ceglarek, A.; Ochab, J. K.; Cifre, I.; Fafrowicz, M.; Sikora-Wachowicz, B.; Lewandowska, K.; Bohaterewicz, B.; Marek, T.; Chialvo, D. R.
10.1101/2021.09.12.459960 — neuroscience — Posted on 2021-09-15
2164 Hobotnica: exploring molecular signature quality
Stupnikov, A.; Sizykh, A.; Favorov, A.; Afsari, B.; Wheelan, S. J.; Marchionni, L.; Medvedeva, Y. A.
10.1101/2021.09.12.459931 — bioinformatics — Posted on 2021-09-15
2165 Causal reasoning over knowledge graphs leveraging drug-perturbed and disease-specific transcriptomic signatures for drug discovery
Domingo-Fernandez, D.; Gadiya, Y.; Patel, A.; Mubeen, S.; Rivas-Barragan, D.; Diana, C.; Misra, B. B.; Healey, D.; Rokicki, J.; Colluru, V.
10.1101/2021.09.12.459579 — bioinformatics — Posted on 2021-09-15
2170 Synthetic Multiantigen MVA Vaccine COH04S1 Protects Against SARS-CoV-2 in Syrian Hamsters and Non-Human Primates
Chiuppesi, F.; Nguyen, V. H.; Park, Y.; Contreras, H.; Karpinski, V.; Faircloth, K.; Nguyen, J.; Kha, M.; Johnson, D.; Martinez, J.; Iniguez, A.; Zhou, Q.; Kaltcheva, T.; Frankel, P.; Kar, S.; Sharma, A.; Andersen, H.; Lewis, M. G.; Shostak, Y.; Wussow, F.; Diamond, D. J.
10.1101/2021.09.15.460487 — immunology — Posted on 2021-09-15
2171 Social boldness in male green anole lizards correlates with baseline vasopressin activity
Kabelik, D.; Julien, A. R.; Waddell, B. R.; Batschelett, M. A.; O'Connell, L. A.
10.1101/2021.09.11.459908 — neuroscience — Posted on 2021-09-15
2173 Myelin imaging of the basal forebrain in first-episode psychosis
Park, M. T. M.; Jeon, P.; French, L. M.; Dempster, K.; Chakravarty, M.; MacKinley, M.; Richard, J.; Khan, A.; Theberge, J.; Palaniyappan, L.
10.1101/2021.09.12.459966 — neuroscience — Posted on 2021-09-15
2176 Amelioration of L-DOPA-induced dyskinesia with vitamin D3 in Parkinsonian mice model
Bayo-Olugbami, A.; Nafiu, A. B.; Amin, A.; Ogundele, O. M.; Lee, C.; Owoyele, B. V.
10.1101/2021.09.13.459937 — neuroscience — Posted on 2021-09-15
2180 High interaction valency ensures cohesion and persistence of a microtubule +TIP body at the plus-end of a single specialized microtubule in yeast
Meier, S. M.; Farcas, A.-M.; Kumar, A.; Ijavi, M.; Bill, R. T.; Stelling, J.; Dufresne, E. R.; Steinmetz, M. O.; Barral, Y.
10.1101/2021.09.13.460064 — cell biology — Posted on 2021-09-15
2181 Genomic and physiological characterization of Novosphingobium terrae sp. nov., an alphaproteobacterium isolated from Cerrado soil containing a megasized chromid
Belmok, A.; Almeida, F. M.; Rocha, R. T.; Vizzotto, C. S.; Totola, M. R.; Ramada, M. H. S.; Krüger, R. H.; Kyaw, C. M.; Pappas Junior, G. J.
10.1101/2021.09.13.460193 — microbiology — Posted on 2021-09-15
2183 Heterodimers of functionally divergent ARF-GEF paralogues prevented by self-interacting dimerisation domain
Jürgens, G.; Brumm, S.; Beckmann, H.; Richter, S.; Singh, M. K.; Huhn, K.; Kucera, T.; Baumann, S.; Kriechbaum, C.; Wolters, H.; Takada, S.
10.1101/2021.09.14.460214 — plant biology — Posted on 2021-09-15
2188 Remote immune processes revealed by immune-derived circulating cell-free DNA
Fox-Fisher, I.; Piyanzin, S.; Klochendler, A.; Ochana, B. L.; Magenheim, J.; Peretz, A.; Loyfer, N.; Moss, J.; Cohen, D.; Drori, Y.; Friedman, N.; Mandelboim, M.; Rothenberg, M. E.; Caldwell, J. M.; Rochman, M.; Jamshidi, A.; Cann, G.; Lavi, D.; Kaplan, T.; Glaser, B.; Shemer, R.; Dor, Y.
10.1101/2021.09.13.460029 — genomics — Posted on 2021-09-15
2191 A novel RAB11-containing adaptor complex anchoring myosin-5 to secretory vesicles
Pinar, M.; Alonso, A. M.; de los Rios, V.; Bravo-Plaza, I.; de la Gandara, A.; Arias-Palomo, E.; Penalva, M. A.
10.1101/2021.09.12.459962 — cell biology — Posted on 2021-09-15
2192 The Lyme Disease agent co-opts adiponectin receptor-mediated signaling in its arthropod vector
Tang, X.; cao, y.; Arora, G.; Hwang, J.; Sajid, A.; Brown, C.; Mehta, S.; Marin-Lopez, A.; Chuang, Y.-M.; Wu, M.-J.; Ma, H.; Pal, U.; Narasimhan, S.; Fikrig, E.
10.1101/2021.09.13.460039 — microbiology — Posted on 2021-09-15
2193 Rapid Identification of Neutralizing Antibodies against SARS-CoV-2 Variants by mRNA Display
Tanaka, S.; Olson, C. A.; Barnes, C. O.; Higashide, W.; Gonzales, M.; Taft, J.; Richardson, A.; Martin-Fernandez, M.; Bogunovic, D.; Gnanapragasam, P. N. P.; Bjorkman, P.; Spilman, P. R.; Niazi, K.; Rabizadeh, S.; Soon-Shiong, P.
10.1101/2021.09.14.460356 — immunology — Posted on 2021-09-15
2195 Combined fluorescence, optical diffraction tomography and Brillouin microscopy
Schlüssler, R.; Kim, K.; Nötzel, M.; Taubenberger, A. V.; Abuhattum, S.; Beck, T.; Müller, P.; Maharana, S.; Cojoc, G.; Girardo, S.; Hermann, A.; Alberti, S.; Guck, J.
10.1101/2020.10.30.361808 — biophysics — Posted on 2021-09-15
2197 Effect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project
Lopera Maya, E. A.; Kurilshikov, A.; van der Graaf, A.; Hu, S.; Andreu-Sanchez, S.; Chen, L.; Vich Villa, A.; Gacesa, R.; Sinha, T.; Collij, V.; Klassen, M.; Bolte, L. A.; Brandao Gois, M. F.; Neerincx, P. B. T.; Swertz, M. A.; Lifelines Cohort Study, ; Harmsen, H. J. M.; Wijmenga, C.; Fu, J.; Weersma, R. K.; Zhernakova, A.; Sanna, S.
10.1101/2020.12.09.417642 — genetics — Posted on 2021-09-15
2198 Endothelial-specific Gata3 expression is required for haematopoietic stem cell generation
Zaidan, N.; Diamanti, E.; Nitsche, L.; Fidanza, A.; Wilson, N.; Forrester, L. M.; Gottgens, B. M.; Ottersbach, K.
10.1101/2021.09.14.460344 — developmental biology — Posted on 2021-09-15
2199 Cdc6 is sequentially regulated by PP2A-Cdc55, Cdc14 and Sic1 for origin licensing in S. cerevisiae
Philip, J.; Ord, M.; Silva, A.; Singh, S.; Diffley, J. F. X.; Remus, D.; Loog, M.; Ikui, A. E.
10.1101/2021.09.14.460335 — cell biology — Posted on 2021-09-15
2200 Comparative analysis of wild type accessions reveals novel determinants of Arabidopsis seed longevity
Ninoles, R.; Planes, D.; Arjona, P.; Ruiz-Pastor, C.; Chazarra, R.; Renard, J.; Bueso, E.; Forment, J.; Serrano, R.; Kranner, I.; Roach, T.; Gadea, J.
10.1101/2021.09.13.460022 — plant biology — Posted on 2021-09-15
2203 Dissecting the allosteric networks governing agonist efficacy and potency in G protein-coupled receptors
Heydenreich, F. M.; Marti-Solano, M.; Sandhu, M.; Kobilka, B. K.; Bouvier, M.; Babu, M. M.
10.1101/2021.09.14.460253 — biochemistry — Posted on 2021-09-15
2204 SDR enzymes oxidize specific lipidic alkynylcarbinols into cytotoxic protein-reactive species
Demange, P.; Joly, E.; Marcoux, J.; Zanon, P. R. A.; Listunov, D.; Rulliere, P.; Barthes, C.; Noirot, C.; Izquierdo, J.-B.; Pradines, K.; Hee, R.; de Brito, M. V.; Marcellin, M.; Serre, R.-F.; Bouchez, O.; Burlet-Schiltz, O.; Oliveira, M. C. F.; Ballereau, S.; Bernardes-Genisson, V.; Maraval, V.; Calsou, P.; Hacker, S. M.; Genisson, Y.; Chauvin, R.; Britton, S.
10.1101/2021.09.15.460423 — biochemistry — Posted on 2021-09-15
2205 Hidden conformations differentiate day and night in a circadian pacemaker
Swan, J.; Sandate, C.; Chavan, A.; Freeberg, A.; Etwaru, D.; Ernst, D.; Palacios, J.; Golden, S.; LiWang, A.; Lander, G. C.; Partch, C.
10.1101/2021.09.14.460370 — biochemistry — Posted on 2021-09-15
2206 Mechanistic basis of choline import involved in teichoic acids and lipopolysaccharide modification
Baerland, N.; Rueff, A. S.; Cebrero, G.; Hutter, C. A. J.; Seeger, M.; Veening, J.-W.; Perez, C.
10.1101/2021.09.14.460277 — biochemistry — Posted on 2021-09-15
2207 Multiplexed profiling of kinase interactomes quantifies cellular network plasticity
Golkowski, M.; Lius, A.; Sapre, T. S.; Lau, H.-T.; Moreno, T.; Maly, D. J.; Ong, S.-E.
10.1101/2021.09.14.460283 — biochemistry — Posted on 2021-09-15
2209 Diversity and composition of cave methanotrophic communities
Webster, K. D.; Schimmelmann, A.; Drobniak, A.; Mastalerz, M.; Rosales Lagarde, L.; Boston, P. J.; Lennon, J. T.
10.1101/412213 — microbiology — Posted on 2021-09-15
2210 ToxoNet: A high confidence map of protein-protein interactions in Toxoplasma gondii reveals novel virulence factors implicated in host cell invasion
Swapna, L.; Stevens, G.; Sardinha da Silva, A.; Hu, L. Z.; Brand, V.; Fusca, D.; Xiong, X.; Boyle, J. P.; Grigg, M. E.; Emili, A.; Parkinson, J.
10.1101/2021.09.14.460186 — microbiology — Posted on 2021-09-15
2211 Hematopoietic-SLC37A2 deficiency accelerates atherosclerosis in LDL receptor-deficient mice
Zhao, Q.; Wang, Z.; Meyers, A.; Madenspacher, J.; Zabalawi, M.; Boudyguina, E.; Hsu, F.-C.; McCall, C.; Furdui, C.; Parks, J.; Fessler, M.; Zhu, X.
10.1101/2021.08.06.455449 — immunology — Posted on 2021-09-15
2212 PhosPiR: An automated phospho-proteomic pipeline in R
Hong, Y.; Flinkman, D.; Suomi, T.; Pietila, S.; James, P.; Coffey, E.; Elo, L. L.
10.1101/2021.09.14.460225 — bioinformatics — Posted on 2021-09-15
2214 Ancestral chromosomes for the Peronosporaceae inferred from a telomere-to-telomere genome assembly of Peronospora effusa.
Fletcher, K.; Shin, O.-H.; Clark, K. J.; Feng, C.; Putman, A. I.; Correll, J. C.; Klosterman, S. J.; Van Deynze, A.; Michelmore, R.
10.1101/2021.09.14.460278 — genomics — Posted on 2021-09-15
2216 Local adaptation shapes metabolic diversity in the global population of Arabidopsis thaliana
Kooke, R.; Kruijer, W.; van Eekelen, H. D. L. M.; Becker, F. F. M.; Wehrens, R.; Hall, R. D.; Mumm, R.; de Vos, R. C. H.; van Eeuwijk, F.; Keurentjes, J. J. B.
10.1101/2021.09.13.460026 — genetics — Posted on 2021-09-15
2218 Almost nontoxic tetrodotoxin analog, 5,6,11-trideoxytetrodotoxin, as an olfactory chemoattractant for the grass puffer
Noguchi, Y.; Suzuki, T.; Matsutani, K.; Nakahigashi, R.; Satake, Y.; Adachi, M.; Nishikawa, T.; Abe, H.
10.1101/2021.09.12.459881 — zoology — Posted on 2021-09-15
2219 Vivarium: an interface and engine for integrative multiscale modeling in computational biology
Agmon, E.; Spangler, R. K.; Skalnik, C. J.; Poole, W.; Peirce, S. M.; Morrison, J. H.; Covert, M. W.
10.1101/2021.04.27.441657 — systems biology — Posted on 2021-09-15
2223 Comprehensive analysis of DNA replication timing in genetic diseases and gene knockouts identifies MCM10 as a novel regulator of the replication program
Caballero, M.; Ge, T.; Rebelo, A. R.; Seo, S.; Kim, S.; Brooks, K.; Zuccaro, M. V.; Kanagaraj, R.; Vershkov, D.; Kim, D.; Smogorzewska, A.; Smolka, M. B.; Benvenisty, N.; West, S. C.; Egli, D. C.; Mace, E. M.; Koren, A.
10.1101/2021.09.08.459433 — genetics — Posted on 2021-09-15
2225 Ecological constraints on highly evolvable olfactory receptor genes and morphology
Yohe, L. R.; Fabbri, M.; Lee, D.; Davies, K.; Yohe, T. P.; Sanchez, M. K.; Rengifo, E.; Hall, R.; Mutumi, G.; Hedrick, B. P.; Sadier, A. A.; Simmons, N. B.; Sears, K. E.; Dumont, E.; Rossiter, S.; Bhullar, B.-A.; Davalos, L.
10.1101/2021.09.06.459178 — evolutionary biology — Posted on 2021-09-15
2227 Tau assemblies enter the cytosol in a cholesterol sensitive process essential to seeded aggregation
Tuck, B. J.; Miller, L. V. C.; Wilson, E. L.; Katsinelos, T.; Cheng, S.; Vaysburd, M. J.; Knox, C.; Tredgett, L.; Metzakopian, E.; James, L. C.; McEwan, W. A.
10.1101/2021.06.21.449238 — cell biology — Posted on 2021-09-15
2228 Trypanosomal variant surface glycoprotein expression in human African trypanosomiasis patients
So, J.; Sudlow, S.; Sayeed, A.; Grudda, T.; Deborggraeve, S.; Ngoyi, D. M.; Desamber, D. K.; Wickstead, B.; Lejon, V.; Mugnier, M. R.
10.1101/2021.09.09.459620 — microbiology — Posted on 2021-09-15
2230 Recombinant NAGLU-IGF2 prevents physical and neurological disease and improves survival in Sanfilippo B syndrome
Le, S. Q.; Kan, S.-h.; Nunez, M.; Dearborn, J. T.; Wang, F.; LI, S.; Snella, L.; Jens, J. K.; Valentine, B. N.; Nelvagal, H. R.; Sorensen, A.; Cooper, J. D.; Chou, T.-F.; Ellinwood, N. M.; Smith, J. D.; Sands, M. S.; Dickson, P.
10.1101/2021.08.06.455469 — neuroscience — Posted on 2021-09-15
2231 Brain stimulation boosts perceptual learning by altering sensory GABAergic plasticity and functional connectivity
Karlaftis, V. M.; Frangou, P.; Higgins, C.; Vidaurre, D.; Ziminski, J. J.; Stagg, C. J.; Emir, U. E.; Kourtzi, Z.
10.1101/2021.09.13.459793 — neuroscience — Posted on 2021-09-15
2232 Disentangling dimensions of animacy in human brain and behaviour
Jozwik, K. M.; Najarro, E.; van den Bosch, J. J.; Charest, I.; Kriegeskorte, N.; Cichy, R. M.
10.1101/2021.09.12.459854 — neuroscience — Posted on 2021-09-15
2234 Shared and unique properties of place cells in anterior cingulate cortex and hippocampus
Bota, A.; Goto, A.; Tsukamoto, S.; Schmidt, A.; Wolf, F.; Luchetti, A.; Nakai, J.; Hirase, H.; Hayashi, Y.
10.1101/2021.03.29.437441 — neuroscience — Posted on 2021-09-15
2236 A histone variant condenses flowering plant sperm via chromatin phase separation
Buttress, T.; He, S.; Wang, L.; Zhou, S.; Sun, L.; Saalbach, G.; Vickers, M.; Li, P.; Feng, X.
10.1101/2021.09.14.460326 — plant biology — Posted on 2021-09-15
2237 Inhibitory Acetylation of Pyruvate Dehydrogenase Promotes Diastolic Dysfunction in Mice
Thapa, D.; Bugga, P.; Mushala, B. A. S.; Manning, J. R.; Stoner, M. W.; McMahon, B.; Xie, B.; Edmunds, L. R.; Jurczak, M. J.; Scott, I.
10.1101/2021.09.07.459319 — physiology — Posted on 2021-09-15
2238 Retinoic acid rewires the adrenergic core regulatory circuitry of neuroblastoma
Zimmerman, M. W.; Durbin, A. D.; He, S.; Oppel, F.; Shi, H.; Tao, T.; Li, Z.; Berezovskaya, A.; Liu, Y.; Zhang, J.; Young, R.; Abraham, B. J.; Look, A. T.
10.1101/2020.07.23.218834 — cancer biology — Posted on 2021-09-15
2239 Feasibility of Administering Human Pancreatic Cancer Chemotherapy in a Spontaneous Pancreatic Cancer Mouse Model
Delahoussaye, A. M.; Jaoude, J. A.; Fujimoto, T. N.; Molkentine, J.; Garcia, C. J. G.; Gay, J. P.; Feng, N.; Marszalek, J.; Taniguchi, C. M.
10.1101/2021.09.08.459476 — cancer biology — Posted on 2021-09-15
2244 Spatial organization of nuclear pores in Xaenopus laevis oocytes
Ravazzano, L.; Bonfanti, S.; Guerra, R.; Montel, F.; La Porta, C. A. M.; Zapperi, S.
10.1101/2021.09.01.458492 — biophysics — Posted on 2021-09-15
2245 A reference tissue atlas for the human kidney
Hansen, J.; Sealfon, R.; Menon, R.; Eadon, M. T.; Lake, B. B.; Steck, B.; Dobi, D.; Parikh, S.; Sidgel, T. K.; Zheng, G.; Velickovic, D.; Barwinska, D.; Alexandrov, T.; Rashmi, P.; Otto, E. A.; Rose, M. P.; Anderton, C. R.; Shapiro, J. P.; Pamreddy, A.; Winfree, S.; He, Y.; de Boer, I. H.; Hodgin, J. B.; Barisoni, L.; Naik, A. S.; Sharma, K.; Sarwal, M. M.; Zhang, K.; Himmelfarb, J.; Rovin, B.; El-Achkar, T. M.; Laszik, Z.; He, J. C.; Dagher, P. C.; Valerius, M. T.; Jain, S.; Satlin, L.; Troyanskaya, O. G.; Kretzler, M.; Iyengar, R.; Azeloglu, E. U.
10.1101/2020.07.23.216507 — bioinformatics — Posted on 2021-09-15
2247 Protein and Lipid Mass Concentration Measurement in Tissues by Stimulated Raman Scattering Microscopy
Oh, S.; Lee, C.; Yang, W.; Li, A.; Ran, C.; Yin, W.; Tabin, C. J.; Fu, D.; Xie, X. S.; Kirschner, M. W.
10.1101/629543 — bioengineering — Posted on 2021-09-15
2248 Axial multi-layer perceptron architecture for automatic segmentation of choroid plexus in multiple sclerosis
Schmidt-Mengin, M.; Ricigliano, V. A. G.; Bodini, B.; Morena, E.; Colombi, A.; Hamzaoui, M.; Yazdan Panah, A.; Stankoff, B.; Colliot, O.
10.1101/2021.09.14.459144 — bioengineering — Posted on 2021-09-15
2250 Proteasome complexes experience profound structural and functional rearrangements throughout mammalian spermatogenesis
Zivkovic, D.; Sanchez Dafun, A.; Menneteau, T.; Schahl, A.; Lise, S.; Kervarrec, C.; Toste-Rego, A.; da Fonseca, P.; Chavent, M.; Pineau, C.; Schiltz, O.; Marcoux, J.; Bousquet, M.-P.
10.1101/2021.06.18.447862 — biochemistry — Posted on 2021-09-15
2254 Sex-specific body mass ageing trajectories in adult Asian elephants
Lalande, L. D.; Lummaa, V.; Aung, H. H.; Htut, W.; Nyein, U. K.; Berger, V.; Briga, M.
10.1101/2020.12.17.423208 — evolutionary biology — Posted on 2021-09-15
2256 Visualizing cellular and tissue ultrastructure using Ten-fold Robust Expansion Microscopy (TREx)
Damstra, H. G. J.; Mohar, B.; Eddison, M.; Akhmanova, A.; Kapitein, L. C.; Tillberg, P. W.
10.1101/2021.02.03.428837 — cell biology — Posted on 2021-09-15
2257 DDX3X and DDX3Y are redundant in protein synthesis
Venkataramanan, S.; Calviello, L.; Wilkins, K.; Floor, S. N.
10.1101/2020.09.30.319376 — molecular biology — Posted on 2021-09-15
2258 Pervasive Translation in Mycobacterium tuberculosis
Smith, C.; Canestrari, J.; Wang, J.; Champion, M. M.; Derbyshire, K.; Gray, T.; Wade, J.
10.1101/665208 — microbiology — Posted on 2021-09-15
2259 Stereotypic expansion of Tregulatory and Th17 cells during infancy is disrupted by HIV exposure and gut epithelial damage.
Dzanibe, S.; Lennard, K.; Kiravu, A.; Seabrook, M. S. S.; Alinde, B.; Holmes, S. P.; Blish, C. A.; Jaspan, H. B.; Gray, C. M.
10.1101/2021.05.03.442468 — immunology — Posted on 2021-09-15
2260 Adolescent female rats undergo full systems consolidation of an aversive memory, while males of the same age fail to discriminate contexts
Crestani, A. P.; Lotz, F. N.; Casagrande, M. A.; Popik, B.; Guerra, K. T. K.; de Oliveira Alvares, L.; Quillfeldt, J. A.
10.1101/2020.08.14.250860 — neuroscience — Posted on 2021-09-15
2264 Common micro- and macroscale principles of connectivity in the human brain
Scholtens, L. H.; Pijnenburg, R.; de Lange, S. C.; (NBB), N. B. B.; Huitinga, I.; van den Heuvel, M. P.
10.1101/2021.09.14.459604 — neuroscience — Posted on 2021-09-15
2271 Disruption of the autism-associated gene SCN2A alters synaptic development and neuronal signaling in patient iPSC-glutamatergic neurons
Brown, C. O.; Uy, J.; Murtaza, N.; Rosa, E.; Afonso, A.; Xing, S.; Dave, B. M.; Kilpatrick, S.; Cheng, A. A.; White, S. H.; Scherer, S. W.; Lu, Y.; Singh, K. K.
10.1101/2021.09.14.460368 — neuroscience — Posted on 2021-09-15
2272 Early stage of Spinocerebellar Ataxia Type 1 (SCA1) progression exhibits region- and cell-specific pathology and is partially ameliorated by Brain Derived Neurotrophic Factor (BDNF)
Rosa, J.-G.; Hamel, K.; Sheeler, C.; Borgenheimer, E.; Gilliat, S.; Soles, A.; Ghannoum, F.; Forster, C.; Rainwater, O.; Orr, H.; Cvetanovic, M.
10.1101/2021.09.13.460129 — neuroscience — Posted on 2021-09-15
2274 Molecular and cellular adaptations in hippocampal parvalbumin neurons mediate behavioral responses to chronic social stress
Bhatti, D. L.; Medrihan, L.; Chen, M. X.; Jin, J.; McCabe, K.; Wang, W.; Azevedo, E. P.; Ledo, J. H.; Kim, Y.
10.1101/2021.09.14.459024 — neuroscience — Posted on 2021-09-15
2280 Extracellular Matrix Stiffness Alters TRPV4 Regulation in Chondrocytes
Trompeter, N. S.; Farino, C. J.; Griffin, M.; Skinner, R.; Banda, O. A.; Gleghorn, J. P.; Slater, J. H.; Duncan, R. L.
10.1101/2021.09.14.460172 — cell biology — Posted on 2021-09-14
2281 Multivalent interactions facilitate motor-dependent protein accumulation at growing microtubule plus ends
Maan, R.; Reese, L.; Volkov, V. A.; King, M. R.; van der Sluis, E.; Andrea, N.; Evers, W.; Jakobi, A. J.; Dogterom, M.
10.1101/2021.09.14.460284 — cell biology — Posted on 2021-09-14
2282 Proteome signatures of reductive stress cardiomyopathy
sunny, s.; David, C. L.; Parasawar, K.; Namakkal-Soorappan, R.
10.1101/2021.09.13.460105 — cell biology — Posted on 2021-09-14
2283 High interaction valency ensures cohesion and persistence of a microtubule +TIP body at the plus-end of a single specialized microtubule in yeast
Meier, S. M.; Farcas, A.-M.; Kumar, A.; Ijavi, M.; Bill, R.; Stelling, J.; Dufresne, E. R.; Steinmetz, M. O.; Barral, Y.
10.1101/2021.09.13.460064 — cell biology — Posted on 2021-09-15
2285 Constitutive loss of DNMT3A causes morbid obesity through misregulation of adipogenesis
Tovy, A.; Reyes, J. M.; Zhang, L.; Huang, Y.-H.; Rosas, C.; Daquinag, A. C.; Guzman, A. G.; Ramabadran, R.; Chen, C.-W.; Gu, T.; Gupta, S.; Ortinau, L.; Park, D.; Cox, A. R.; Rau, R. E.; Hartig, S. M.; Kolonin, M. G.; Goodell, M. A.
10.1101/2021.09.13.460063 — cell biology — Posted on 2021-09-15
2286 Identification of two pathways mediating protein targeting from ER to lipid droplets
Song, J.; Mizrak, A.; Lee, C.-W.; Cicconet, M.; Lai, Z. W.; Lu, C.-H.; Mohr, S. E.; Farese, R. V.; Walther, T. C.
10.1101/2021.09.14.460330 — cell biology — Posted on 2021-09-15
2287 Regional Cell Atlas of Human Intestine Shapes Distinct Immune Surveillance
Wang, Y.; Yu, Y.; Li, L.; Zheng, M.; Zhou, J.; Gong, H.; Feng, B.; Qu, J.; Li, Z.; Ji, R.; Lu, M.; Yang, X.; Zuo, X.; Li, S.; Li, Y.
10.1101/2021.09.13.459999 — cell biology — Posted on 2021-09-15
2293 Automated satellite remote sensing of giant kelp at the Falkland Islands (Islas Malvinas)
Houskeeper, H. F.; Rosenthal, I. S.; Cavanaugh, K. C.; Pawlak, C.; Trouille, L.; Byrnes, J. E. K.; Bell, T. W.; Cavanaugh, K. C.
10.1101/2021.09.14.460404 — ecology — Posted on 2021-09-14
2295 Human rare variant and zebrafish CRISPR/Cas9-mediated mutant analyses reveal novel functions for API5, HSPB7, and LMO2 in heart failure
Winter, M. J.; Ono, Y.; Ball, J. S.; Walentinsson, A.; Michaelsson, E.; Tochwin, A.; Scholpp, S.; Tyler, C. R.; Rees, S.; Hetheridge, M. J.; Bohlooly-Y, M.
10.1101/2021.09.14.460241 — molecular biology — Posted on 2021-09-14
2296 "Understanding Cortical Arousals during Sleep from Leg Movements: A Pilot Study."
Bansal, K.; Garcia, J.; Feltch, C.; Earley, C.; Robucci, R.; Banerjee, N.; Brooks, J.
10.1101/2021.09.14.460395 — neuroscience — Posted on 2021-09-14
2298 Global mapping of the energetic and allosteric landscapes of protein binding domains
Faure, A. J.; Domingo, J.; Schmiedel, J. M.; Hidalgo-Carcedo, C.; Diss, G.; Lehner, B.
10.1101/2021.09.14.460249 — biophysics — Posted on 2021-09-14
2303 Predicting Individual Cell Division Events from Single-Cell ERK and Akt Dynamics
Stern, A. D.; Smith, G. R.; Santos, L. C.; Sarmah, D.; Zhang, X.; Lu, X.; Iuricich, F.; Pandey, G.; Iyengar, R.; Birtwistle, M. R.
10.1101/2021.09.14.460349 — systems biology — Posted on 2021-09-14
2305 Elevated phosphorylation of EGFR in NSCLC due to mutations in PTPRH
Swiatnicki, M. R.; Rennhack, J. P.; Hollern, D.; Perry, A. V.; Kubiak, R.; Riveria Riveria, S. M.; O'Reilly, S.; Andrechek, E. R.
10.1101/2021.09.14.460311 — cancer biology — Posted on 2021-09-14
2306 Germline Missense Variants in CDC20 Result in Aberrant Mitotic Progression and Familial Cancer
Chen, O. J.; Castellsague, E.; Moustafa-Kamal, M.; Nadaf, J.; Rivera, B.; Fahiminiya, S.; Wang, Y.; Gamache, I.; Pacifico, C.; Jiang, L.; Carrot-Zhang, J.; Witkowski, L.; Berghuis, A. M.; Schoenberger, S.; Schneider, D.; Bens, S.; Siebert, R.; Stewart, C. J. R.; Zhang, Z.; Chao, W. C.; Greenwood, C. M. T.; Barford, D.; Tischkowitz, M.; Majewski, J.; Foulkes, W. D.; Teodoro, J. G.
10.1101/2021.09.13.459529 — cancer biology — Posted on 2021-09-14
2307 Enhanced Specificity Mutations Perturb Allosteric Signaling in CRISPR-Cas9
Palermo, G.; Nierzwicki, L.; East, K. W.; Morzan, U. N.; Arantes, P. R.; Lisi, G. P.; Batista, V. S.
10.1101/2021.09.14.460226 — biophysics — Posted on 2021-09-14
2308 Allosteric modulation of the adenosine A2A receptor by cholesterol
Huang, S. K.; Almurad, O.; Pejana, R. J.; Morrison, Z. A.; Pandey, A.; Picard, L.-P.; Nitz, M.; Sljoka, A.; Prosser, R. S.
10.1101/2021.09.13.460151 — biophysics — Posted on 2021-09-14
2312 Structure of a bacterial Rhs effector exported by the type VI secretion system
Guenther, P.; Quentin, D.; Ahmad, S.; Sachar, K.; Gatsogiannis, C.; Whitney, J.; Raunser, S.
10.1101/2021.09.14.460138 — biochemistry — Posted on 2021-09-14
2313 Structural basis for mismatch surveillance by CRISPR/Cas9
Bravo, J. P.; Liu, M.-S.; McCool, R. S.; Jung, K.; Johnson, K. A.; Taylor, D. W.
10.1101/2021.09.14.460224 — biochemistry — Posted on 2021-09-14
2315 Monomeric IgA antagonizes IgG-mediated enhancement of DENV infection
Wegman, A.; Fang, H.; Rothman, A. L.; Thomas, S. J.; Endy, T. P.; McCracken, M. K.; Currier, J. R.; Friberg, H.; Gromowski, G. D.; Waickman, A. T.
10.1101/2021.09.14.460347 — immunology — Posted on 2021-09-14
2316 Characterizing cellular heterogeneity in chromatin state with scCUT&Tag-pro
Zhang, B.; Srivastava, A.; Mimitou, E.; Stuart, T.; Raimondi, I.; Hao, Y.; Smibert, P.; Satija, R.
10.1101/2021.09.13.460120 — genomics — Posted on 2021-09-14
2320 Interaction between BID and VDAC1 is required for mitochondrial demise and cell death in neurons
Oppermann, S.; Mertins, B.; Meissner, L.; Krasel, C.; Psakis, G.; Reiss, P.; Dolga, A. M.; Plesnila, N.; Essen, L.-O.; Culmsee, C.
10.1101/2021.09.14.460262 — molecular biology — Posted on 2021-09-14
2321 Selective Modulator of Nuclear Receptor PPARy with Reduced Adipogenic Potential Ameliorates Experimental Nephrotic Syndrome
Burton, C.; Rask, G.; Waller, A. P.; Webb, A.; Galdino-Pitta, M. R.; Amato, A. A.; Cianciolo, R.; Becknell, B.; Kerlin, B. A.; Neves, F. A. R.; Fornoni, A.; Agrawal, S.
10.1101/2021.09.14.459479 — molecular biology — Posted on 2021-09-14
2324 Associations and recovery dynamics of the nasopharyngeal microbiota during influenza-like illness in the aging population
Shetty, S. A.; van Beek, J.; Bijvank, E.; Groot, J.; Kuiling, S.; Bosch, T.; van Baarle, D.; Fuentes, S.
10.1101/2021.09.14.458655 — microbiology — Posted on 2021-09-14
2328 Isolation, identification and molecular characterization of Aeromonas spp. from farmed loach (Misgurnus anguillicaudatus)
Wang, X.; Pan, J.; Chen, L.; Li, R.; Han, Y.; Di, Z.; Ling, B.; Ahmad, A. A.; Yang, N.; Fan, L.; Li, Q.; Zeng, J.; Guo, G.; Zheng, J.
10.1101/2021.09.13.460194 — microbiology — Posted on 2021-09-14
2330 Development of a novel, pan-variant aerosol intervention for COVID-19
Shoemaker, R. H.; Panettieri, R. A.; Libutti, S. K.; Hochster, H. S.; Watts, N. R.; Wingfield, P. T.; Starkl, P. M.; Pimenov, L.; Gawish, R.; Hladik, A.; Knapp, S.; Boring, D.; White, J. M.; Lawrence, Q.; Boone, J.; Marshall, J. D.; Matthews, R. L.; Cholewa, B. D.; Richig, J. W.; Chen, B. T.; McCormick, D. L.; Gugensberger, R.; Holler, S.; Penninger, J. M.; Wirnsberger, G.
10.1101/2021.09.14.459961 — pharmacology and toxicology — Posted on 2021-09-14
2332 Fragment-based ab initio phasing of peptidic nanocrystals by MicroED
Richards, L.; Flores, M. D.; Millan, C.; Zee, C.-T.; Glynn, C.; Sawaya, M. R.; Gallagher-Jones, M.; Borges, R.; Uson, I.; Rodriguez, J. A.
10.1101/2021.09.13.459692 — biochemistry — Posted on 2021-09-14
2333 Therapeutic efficacy of an oral nucleoside analog of remdesivir against SARS-CoV-2 pathogenesis in mice.
Schafer, A.; Martinez, D. R.; Won, J. J.; Moreira, F. R.; Brown, A. J.; Gully, K. L.; Kalla, R.; Chun, K.; Du Pont, V.; Babusis, D.; Tang, J.; Murakami, E.; Subramanian, R.; Barrett, K. T.; Bleier, B. J.; Bannister, R.; Feng, J. Y.; Bilello, J. P.; Cihlar, T.; Mackman, R. L.; Montgomery, S. A.; Baric, R. S.; Sheahan, T. P.
10.1101/2021.09.13.460111 — microbiology — Posted on 2021-09-14
2334 A screen for mutants deficient in coronatine-mediated suppression of root immunity identifies Arabidopsis SDA1 as a novel integrator of immunity and phytohormone signaling
Song, Y.; Zhang, X.-C.; Qiu, Y.; Briggs, A.; Millet, Y.; Bartenstein, D.; Mankiw, C.; Cerulli, M. L.; Bush, J.; Adams, K. L.; Diener, A. C.; Ausubel, F. M.; Haney, C. H.
10.1101/2021.09.12.459990 — plant biology — Posted on 2021-09-14
2337 Effect of ORF7 of SARS-CoV-2 on the chemotaxis of monocytes and neutrophils in vitro
Wang, G.; Guan, J.; Li, G.; Wu, F.; Yang, Q.; Huang, C.; Shao, J.; Xu, L.; Guo, Z.; Zhou, Q.; Zhu, H.; Chen, Z.
10.1101/2021.09.13.460185 — cell biology — Posted on 2021-09-14
2338 Protective Efficacy of Gastrointestinal SARS-CoV-2 Delivery Against Intranasal and Intratracheal SARS-CoV-2 Challenge in Rhesus Macaques
Yu, J.; Collins, N.; Mercado, N. B.; McMahan, K.; Chandrashekar, A.; Liu, J.; Anioke, T.; Chang, A.; Giffin, V.; Hope, D.; Sellers, D.; Nampanya, F.; Gardner, S.; Barrett, J.; Wan, H.; Velasco, J.; Teow, E.; Cook, A.; Van Ry, A.; Pessaint, L.; Andersen, H.; Lewis, M.; Hofer, C.; Burke, D. S.; Barkei, E.; King, H.; Subra, C.; Bolton, D. L.; Modjarrad, K.; Michael, N.; Barouch, D. H.
10.1101/2021.09.13.460191 — microbiology — Posted on 2021-09-14
2339 BNT162b2-Elicited Neutralization of Delta Plus, Lambda, and Other Variants
Liu, J.; Liu, Y.; Xia, H.; Zou, J.; Weaver, S.; Swanson, K. A.; Cai, H.; Cutler, M.; Cooper, D.; Muik, A.; Jansen, K. U.; Sahin, U.; Xie, X.; Dormitzer, P. R.; Shi, P.-Y.
10.1101/2021.09.13.460163 — microbiology — Posted on 2021-09-14
2340 Bile acids gate dopamine transporter mediated currents
Romanazzi, T.; Zanella, D.; Cheng, M. H.; Smith, B.; Carter, A. M.; Galli, A.; Bahar, I.; Bossi, E.
10.1101/2021.09.13.459497 — neuroscience — Posted on 2021-09-14
2341 Molecular basis of differential adventitious rooting competence in poplar genotypes
Ranjan, A.; Perrone, I.; Alallaq, S.; Singh, R.; Rigal, A.; Brunoni, F.; Chitarra, W.; Guinet, F.; Kohler, A.; Martin, F.; Street, N. R.; Bhalerao, R.; Legue, V.; Bellini, C.
10.1101/2021.09.14.460203 — plant biology — Posted on 2021-09-14
2342 A histone variant condenses flowering plant sperm via chromatin phase separation
Buttress, T.; He, S.; Wang, L.; Zhou, S.; Sun, L.; Saalbach, G.; Vickers, M.; Li, P.; Feng, X.
10.1101/2021.09.14.460326 — plant biology — Posted on 2021-09-14
2343 SARS-CoV-2 Spike Protein Regulation of Angiotensin Converting Enzyme 2 and Tissue Renin-Angiotensin Systems: Influence of Biologic Sex
Ensor, C. M.; AlSiraj, Y.; Shoemaker, R.; Sturgill, J.; Keshavamurthy, S.; Gordon, E.; Dong, B.; Waters, C. M.; Cassis, L. C.
10.1101/2021.09.14.460275 — physiology — Posted on 2021-09-14
2345 Decoding the olfactory map: targeted transcriptomics link olfactory sensory neurons to glomeruli
Zhu, K. W.; Burton, S. D.; Nagai, M. H.; Silverman, J. D.; de March, C. A.; Wachowiak, M.; Matsunami, H.
10.1101/2021.09.13.460128 — neuroscience — Posted on 2021-09-14
2351 Peroxide antimalarial drugs target redox homeostasis in Plasmodium falciparum infected red blood cells
Siddiqui, G.; Giannangelo, C.; De Paoli, A. E.; Schuh, A. K.; Heimsch, K.; Anderson, D.; Brown, T. G.; MacRaild, C. A.; Wu, J.; Wang, X.; Dong, Y.; Vennerstrom, J. L.; Becker, K.; Creek, D. J.
10.1101/2021.09.10.459878 — pharmacology and toxicology — Posted on 2021-09-14
2353 Ear pinnae in a neotropical katydid function as ultrasound guides for bat call detection
Pulver, C.; Celiker, E.; Woodrow, C.; Geipel, I.; Soulsbury, C.; Cullen, D.; Veitch, D.; Montealegre-Z, F.
10.1101/2021.09.01.458595 — biophysics — Posted on 2021-09-14
2354 Thymidine starvation promotes c-di-AMP dependent inflammation during infection
Tang, Q.; Precit, M.; Thomason, M.; Ahmed-Qadri, F.; McFarland, A.; Wolter, D.; Hoffman, L.; Woodward, J. J.
10.1101/2020.08.21.261750 — molecular biology — Posted on 2021-09-14
2361 Heritable changes in division speed accompany the diversification of singleT cell fate
Plambeck, M.; Kazeroonian, A.; Loeffler, D.; Schroeder, T.; Busch, D. H.; Flossdorf, M.; Buchholz, V. R.
10.1101/2021.07.28.454102 — immunology — Posted on 2021-09-14
2363 NeuroML-DB: Sharing and characterizing data-driven neuroscience models described in NeuroML
Birgiolas, J.; Haynes, V.; Gleeson, P.; Gerkin, R. C.; Dietrich, S. W.; Crook, S. M.
10.1101/2021.09.11.459920 — neuroscience — Posted on 2021-09-14
2364 Predictive coding during action observation - a depth-resolved intersubject functional correlation study at 7T
Cerliani, L.; Bhandari, R.; De Angelis, L.; van der Zwaag, W.; Bazin, P.-L.; Gazzola, V.; Keysers, C.
10.1101/2021.08.30.458143 — neuroscience — Posted on 2021-09-14
2365 Physiological and transcriptomic response of Medicago truncatula to high and low benefit mycorrhizal fungi
Cope, K. R.; Kafle, A.; Yakha, J. K.; Pfeffer, P. E.; Strahan, G. D.; Garcia, K.; Subramanian, S.; Bucking, H.
10.1101/2020.12.11.421693 — plant biology — Posted on 2021-09-14
2367 Late adolescence mortality in mice with brain-specific deletion of the volume-regulated anion channel subunit LRRC8A
Wilson, C. S.; Dohare, P.; Orbeta, S.; Nalwalk, J. W.; Huang, Y.; Ferland, R. J.; Sah, R.; Scimemi, A.; Mongin, A. A.
10.1101/2020.05.22.109462 — neuroscience — Posted on 2021-09-14
2370 Child abuse associates with increased recruitment of perineuronal nets in the ventromedial prefrontal cortex: a possible implication of oligodendrocyte progenitor cells
Tanti, A.; Belliveau, C.; Nagy, C.; Maitra, M.; Denux, F.; Perlman, K.; Chen, F.; Mpai, R.; Canonne, C.; Theberge, S.; McFarquhar, A.; Davoli, M. A.; Belzung, C.; Turecki, G.; Mechawar, N.
10.1101/2020.10.19.345355 — neuroscience — Posted on 2021-09-14
2371 Shared genetic influences on resting-state functional networks of the brain
Guimaraes, J. P. O. F. T.; Sprooten, E.; Beckmann, C. F.; Franke, B.; Bralten, J.
10.1101/2021.02.15.431231 — neuroscience — Posted on 2021-09-14
2372 Genome of a Giant (Trevally): Caranx ignobilis
Pickett, B. D.; Glass, J. R.; Ridge, P. G.; Kauwe, J. S.
10.1101/2021.09.11.459923 — genomics — Posted on 2021-09-14
2379 Stomatal responses at different vegetative stages of selected maize varieties of Bangladesh under water deficit condition
Abdul-Awal, S. M.; Moin Uddin Talukder, M.; Debnath, P.; Nasrin, S.; Akter, S.; Ali, M. R.; Islam, M. R.
10.1101/2021.09.13.460018 — plant biology — Posted on 2021-09-13
2380 Glucose controls co-translation of structurally related mRNAs via the mTOR and eIF2 pathways in human pancreatic beta cells
Bulfoni, M.; Bouyioukos, C.; Zakaria, A.; Nigon, F.; Rapone, R.; Del Maestro, L.; Ait-Si-Ali, S.; Scharfmann, R.; Cosson, B.
10.1101/2021.09.13.460006 — genomics — Posted on 2021-09-13
2381 The key features of SARS-CoV-2 leader and NSP1 required for viral escape of NSP1-mediated repression
Bujanic, L.; Shevchuk, O.; von Kuegelgen, N.; Ludwik, K.; Koppstein, D.; Zerna, N.; Sickmann, A.; Chekulaeva, M.
10.1101/2021.09.13.460054 — molecular biology — Posted on 2021-09-13
2382 Variants in ALDH1A2 reveal an anti-inflammatory role for retinoic acid and a new class of disease-modifying drugs in osteoarthritis
Zhu, L.; Kamalathevan, P.; Koneva, L.; Miotla Zarebska, J.; Chanalaris, A.; Ismail, H.; Wiberg, A.; Ng, M.; Muhammed, H.; Watt, F.; Sansom, S.; Furniss, D.; Gardiner, M.; Vincent, T. L.
10.1101/2021.09.10.457848 — molecular biology — Posted on 2021-09-13
2384 Targeting mitochondrial double-stranded RNAs ameliorates autoimmune characteristics of Sjogrens syndrome
Yoon, J.; Lee, M. S.; Ali, A. A.; Oh, Y. R.; Choi, Y. S.; Kim, S.; Lee, N.; Jang, S. G.; Ahamad, N.; Kwok, S.-K.; Hyon, J. Y.; Cha, S.; Lee, Y. J.; Im, S. G.; Kim, Y.
10.1101/2021.09.13.459934 — molecular biology — Posted on 2021-09-13
2385 Structural architecture of a dimeric paramyxovirus polymerase complex
Xie, J.; Wang, L.; Zhai, G.; Wu, D.; Lin, Z.; Wang, M.; Yan, X.; Gao, L.; Huang, X.; Fearns, R.; Chen, S.
10.1101/2021.09.13.460081 — molecular biology — Posted on 2021-09-13
2387 Systemic and local immune response to intraocular AAV vector administration in non-human primates
Ail, D.; Ren, D.; Brazhnikova, E.; Jaillard, C.; Bertin, S.; Fisson, S.; Dalkara, D.
10.1101/2021.09.13.460058 — immunology — Posted on 2021-09-13
2390 Multiplexed identification of RAS paralog imbalance as a driver of lung cancer growth
Tang, R.; Shuldiner, E. G.; Kelly, M.; Murray, C. W.; Hebert, J. D.; Andrejka, L.; Tsai, M. K.; Hughes, N. W.; Parker, M. I.; Cai, H.; Li, Y.-C.; Wahl, G.; Dunbrack, R.; Jackson, P. K.; Petrov, D.; Winslow, M. M.
10.1101/2021.07.08.451571 — cancer biology — Posted on 2021-09-13
2392 Distinct roles of glutamine metabolism in benign and malignant cartilage tumors with IDH mutations
Zhang, H.; Puviindran, V.; Nadesan, P.; Ding, X.; Shen, L.; Tang, Y. J.; Tsushima, H.; Yahara, Y.; Ban, G. I.; Zhang, G.-F.; Karner, C. M.; Alman, B. A.
10.1101/2021.09.12.459996 — cancer biology — Posted on 2021-09-13
2398 Transcriptome and proteome profiling reveals complex adaptations of Candida parapsilosis cells assimilating hydroxyaromatic carbon sources
Cillingova, A.; Toth, R.; Mojakova, A.; Zeman, I.; Vrzonova, R.; Sivakova, B.; Barath, P.; Nebohacova, M.; Klepcova, Z.; Brazdovic, F.; Lichancova, H.; Hodorova, V.; Brejova, B.; Vinar, T.; Tomaska, L.; Gacser, A.; Gabaldon, T.; Nosek, J.
10.1101/2021.09.13.460007 — genomics — Posted on 2021-09-13
2400 Gsx2 but not Gsx1 is necessary for early forebrain patterning and long-term survival in zebrafish
Coltogirone, R. A.; Sherfinski, E. I.; Dobler, Z. A.; Peterson, S. N.; Andlinger, A. R.; Fadel, L. C.; Patrick, R. L.; Bergeron, S. A.
10.1101/2021.09.13.460150 — developmental biology — Posted on 2021-09-13
2402 How Dickkopf molecules and Wnt/beta-catenin interplay to self-organise the Hydra body axis
Mercker, M.; Kazarnikov, A.; Tursch, A.; Özbek, S.; Holstein, T. W.; Marciniak-Czochra, A.
10.1101/2021.09.13.460125 — developmental biology — Posted on 2021-09-13
2403 Human iPSC-Based Model Reveals NOX4 as Therapeutic Target in Duchenne Cardiomyopathy
Duelen, R.; Costamagna, D.; Gilbert, G.; De Waele, L.; Goemans, N.; Desloovere, K.; Verfaillie, C. M.; Sipido, K. R.; Buyse, G. M.; Sampaolesi, M.
10.1101/2021.09.13.460090 — developmental biology — Posted on 2021-09-13
2404 Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage
Cao, K.; Riley, J. S.; Cloix, C.; Elmasry, Y.; Ichim, G.; Campbell, K. J.; Tait, S. W.
10.1101/2021.09.13.460067 — cell biology — Posted on 2021-09-13
2405 Mimicking extracellular matrix-mediated mechano-activation by antibodies to control signaling of the adhesion G protein-coupled receptor GPR126/ADGRG6
Mitgau, J.; Franke, J.; Schinner, C.; Stephan, G.; Berndt, S.; Placantonakis, D. G.; Kalwa, H.; Spindler, V.; Wilde, C.; Liebscher, I.
10.1101/2021.09.13.460127 — molecular biology — Posted on 2021-09-13
2407 TRIM25 inhibits Influenza A infection by destabilising its mRNA and is redundant for the RIG-I pathway.
Choudhury, N. R.; Heikel, G.; Trus, I.; Pinto, R. M. D. S.; Trubitsyna, M.; Gaunt, E. R.; Digard, P.; Michlewski, G.
10.1101/2021.09.13.460052 — molecular biology — Posted on 2021-09-13
2408 CTCF and cohesin promote focal detachment of DNA from the nuclear lamina
van Schaik, T.; Liu, N. Q.; Manzo, S. G.; Peric-Hupkes, D.; de Wit, E.; van Steensel, B.
10.1101/2021.09.13.460079 — molecular biology — Posted on 2021-09-13
2413 BashTheBug: a crowd of volunteers reproducibly and accurately measure the minimum inhibitory concentrations of 13 antitubercular drugs from photographs of 96-well broth microdilution plates.
Fowler, P. W.; Wright, C.; Spiers, H.; Zhu, T.; Baeten, E. M.; Hoosdally, S. W.; Gibertoni Cruz, A. L.; Roohi, A.; Kouchaki, S.; Walker, T. M.; Peto, T. E.; Miller, G.; Lintott, C.; Clifton, D.; Crook, D. W.; Walker, A. S.; The Zooniverse Volunteer Community, ; The CRyPTIC Consortium,
10.1101/2021.07.20.453060 — microbiology — Posted on 2021-09-13
2414 Chromodomain protein regulates the expression of a subset of RIFINs in P. falciparum
Sethumadhavan, D. V.; Tiburcio, M.; Kanyal, A.; Jabeena, C.; Govindaraju, G.; Karmodiya, K.; Rajavelu, A.
10.1101/2021.09.13.460021 — microbiology — Posted on 2021-09-13
2416 The predicted bZIP transcription factor ZIP-1 promotes resistance to intracellular infection in Caenorhabditis elegans
Lazetic, V.; Wu, F.; Cohen, L. B.; Reddy, K. C.; Chang, Y.-T.; Gang, S. S.; Bhabha, G.; Troemel, E. R.
10.1101/2021.06.17.448850 — immunology — Posted on 2021-09-13
2419 Local neuronal excitation and global inhibition during epileptic fast ripples in humans.
Curot, J.; Barbeau, E. J.; Despouy, E.; Denuelle, M.; Sol, J. C.; Lotterie, J.-A.; Valton, L.; Peyrache, A.
10.1101/2021.09.09.459695 — neuroscience — Posted on 2021-09-13
2421 Identification of a stereotypic molecular arrangement of endogenous glycine receptors at spinal cord synapses
Maynard, S. A.; Rostaing, P.; Schaefer, N.; Gemin, O.; Candat, A.; Dumoulin, A.; Villmann, C.; Triller, A.; Specht, C. G.
10.1101/2021.09.09.459599 — neuroscience — Posted on 2021-09-13
2422 Decoding natural astrocyte rhythms: dynamic actin waves result from environmental sensing by primary rodent astrocytes
O'Neill, K. M.; Saracino, E.; Barile, B.; Mennona, N. J.; Mola, M. G.; Pathak, S.; Posati, T.; Zamboni, R.; Nicchia, G. P.; Benfenati, V.; Losert, W.
10.1101/2021.09.13.460152 — neuroscience — Posted on 2021-09-13
2427 ProtAnno, an Automated Cell Type Annotation Tool for Single Cell Proteomics Data that Integrates Information from Multiple Reference Sources
Deng, W.; Zhu, B.; Park, S.; Sumida, T. S.; Unterman, A.; Hafler, D. A.; Cruz, C. S. D.; Kaminski, N.; Lucas, C. L.; Zhao, H.-y.
10.1101/2021.09.13.460162 — bioinformatics — Posted on 2021-09-13
2430 Acoustic frequency-dependent physical mechanism of sub-MHz ultrasound neurostimulation
Fan, H.; Shimba, K.; Ishijima, A.; Sasaoka, K.; Takahashi, T.; Chang, C.-H.; Jimbo, Y.; Azuma, T.; Takagi, S.
10.1101/2021.09.11.458049 — bioengineering — Posted on 2021-09-13
2434 Competition Between Cell-Cell and Cell-Substrate Adhesion Determines Epithelial Monolayer Architecture in Culture
Cammarota, C. M.; Dawney, N. S.; Jia, Q.; Jung, M. M.; Glichowski, J. A.; Bellomio, P. M.; Fletcher, A. G.; Bergstralh, D. T.
10.1101/2021.09.13.460154 — cell biology — Posted on 2021-09-13
2437 15-PGDH Regulates Hematopoietic and Gastrointestinal Fitness During Aging
Ho, W. J.; Smith, J. N. P.; Park, Y. S.; Hadiono, M.; Christo, K. F.; Jogasuria, A.; Zhang, Y.; Broncano, A. V.; Kasturi, L.; Dawson, D. M.; Gerson, S. L.; Markowitz, S. D.; Desai, A. B.
10.1101/2020.12.22.424017 — pathology — Posted on 2021-09-13
2438 AxonDeep: Automated Optic Nerve Axon Segmentation in Mice with Deep Learning.
Deng, W.; Hedberg-Buenz, A.; Soukup, D. A.; Taghizadeh, S.; Wang, K.; Anderson, M. G.; Garvin, M. K.
10.1101/2021.05.21.445196 — bioengineering — Posted on 2021-09-13
2441 Denisovan introgression has shaped the immune system of present-day Papuans
Vespasiani, D. M.; Jacobs, G. S.; Cook, L. E.; Brucato, N.; Leavesley, M.; Kinipi, C.; Ricaut, F. X.; Cox, M. P.; Gallego Romero, I.
10.1101/2020.07.09.196444 — evolutionary biology — Posted on 2021-09-13
2442 Heterogeneous mutation rates and spectra in yeast hybrids
Fijarczyk, A.; Henault, M.; Marsit, S.; Charron, G.; Landry, C. R.
10.1101/2021.06.04.447117 — evolutionary biology — Posted on 2021-09-13
2446 Maintenance of mitochondrial integrity in midbrain dopaminergic neurons governed by a conserved developmental transcription factor
Miozzo, F.; Stickley, L.; Valencia-Alarcon, E. P.; Dorcikova, M.; Petrelli, F.; Tas, D.; Loncle, N.; Nikonenko, I.; Bou Dib, P.; Nagoshi, E.
10.1101/2020.07.24.219246 — neuroscience — Posted on 2021-09-13
2448 Visualizing synaptic plasticity in vivo by large-scale imaging of endogenous AMPA receptors
Graves, A. R.; Roth, R.; Tan, H.; Zhu, Q.; Bygrave, A.; Lopez-Ortega, E.; Spiegel, A.; Hong, I.; Johnson, R.; Vogelstein, J.; Tward, D.; Miller, M.; Huganir, R. L.
10.1101/2020.03.01.972216 — neuroscience — Posted on 2021-09-13
2450 A hybrid open-top light-sheet microscope for multi-scale imaging of cleared tissues
Glaser, A. K.; Bishop, K. W.; Barner, L. A.; Susaki, E. A.; Kubota, S. I.; Gao, G.; Serafin, R. B.; Balaram, P.; Turschak, E.; Nicovich, P. R.; Lai, H.; Lucas, L. A. G.; Yi, Y.; Nichols, E. K.; Huang, H.; Reder, N. P.; Wilson, J. J.; Sivakumar, R.; Shamskhou, E.; Stoltzfus, C. R.; Wei, X.; Hempton, A. K.; Pende, M.; Murawala, P.; Dodt, H. U.; Imaizumi, T.; Shendure, J.; Beliveau, B. J.; Gerner, M. Y.; Xin, L.; Zhao, H.; True, L. D.; Reid, R. C.; Chandrashekar, J.; Ueda, H. R.; Svoboda, K.; Liu, J. T. C.
10.1101/2020.05.06.081745 — bioengineering — Posted on 2021-09-13
2451 Effect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project
Lopera Maya, E. A.; Kurilshikov, A.; van der Graaf, A.; Hu, S.; Andreu-Sanchez, S.; Chen, L.; Vich Villa, A.; Gacesa, R.; Sinha, T.; Collij, V.; Klassen, M.; Bolte, L. A.; Brandao Gois, M. F.; Neerincx, P. B. T.; Swertz, M. A.; Lifelines Cohort Study, ; Harmsen, H. J. M.; Wijmenga, C.; Fu, J.; Weersma, R. K.; Zhernakova, A.; Sanna, S.
10.1101/2020.12.09.417642 — genetics — Posted on 2021-09-13
2453 Visual and auditory brain areas share a representational structure that supports emotion perception
Sievers, B.; Parkinson, C.; Kohler, P. J.; Hughes, J. M.; Fogelson, S. V.; Wheatley, T.
10.1101/254961 — neuroscience — Posted on 2021-09-13
2455 Structure-activity relationships of B.1.617 and other SARS-CoV-2 spike variants
Yang, T.-J.; Yu, P.-Y.; Chang, Y.-C.; Chang, N.-E.; Tsai, Y.-X.; Liang, K.-H.; Draczkowski, P.; Lin, B.; Wang, Y.-S.; Chien, Y.-C.; Khoo, K.-H.; Wu, H.-C.; Hsu, S.-T. D.
10.1101/2021.09.12.459978 — biophysics — Posted on 2021-09-13
2458 Pharmacological perturbation of intracellular dynamics as a SARS-CoV-2 antiviral strategy
Bakhache, W.; Partiot, E.; Lucansky, V.; Bare, Y.; Bonaventure, B.; Goujon, C.; Bories, C.; Deffieu, M. S.; Gaudin, R.
10.1101/2021.09.10.459410 — microbiology — Posted on 2021-09-13
2459 Elicitation of potent SARS-CoV-2 neutralizing antibody responses through immunization using a versatile adenovirus-inspired multimerization platform
Chevillard, C.; Amen, A.; Besson, S.; Hannani, D.; Bally, I.; Dettling, V.; Gout, E.; Moreau, C. J.; Buisson, M.; Gallet, S.; Fenel, D.; Vassal-Stermann, E.; Schoehn, G.; Poignard, P.; Dagher, M.-C.; Fender, P.
10.1101/2021.09.13.460076 — microbiology — Posted on 2021-09-13
2461 A rapid, highly sensitive and open-access SARS-CoV-2 detection assay for laboratory and home testing
Kellner, M. J.; Ross, J. J.; Schnabl, J.; Dekens, M. P. S.; Heinen, R.; Grishkovskaya, I.; Bauer, B.; Stadlmann, J.; Menendez-Arias, L.; Fritsche-Polanz, R.; Traugott, M.; Seitz, T.; Zoufaly, A.; Foedinger, M.; Wenisch, C.; Zuber, J.; Vienna Covid-19 Diagnostics Initiative (VCDI), ; Pauli, A.; Brennecke, J.
10.1101/2020.06.23.166397 — molecular biology — Posted on 2021-09-13
2462 Therapeutic efficacy of an oral nucleoside analog of remdesivir against SARS-CoV-2 pathogenesis in mice.
Schafer, A.; Martinez, D. R.; Won, J. J.; Moreira, F. R.; Brown, A. J.; Gully, K. L.; Kalla, R.; Chun, K.; Du Pont, V.; Babusis, D.; Tang, J.; Murakami, E.; Subramanian, R.; Barrett, K. T.; Bleier, B. J.; Bannister, R.; Feng, J. Y.; Bilello, J. P.; Cihlar, T.; Mackman, R. L.; Montgomery, S. A.; Baric, R. S.; Sheahan, T. P.
10.1101/2021.09.13.460111 — microbiology — Posted on 2021-09-13
2466 Closed-Loop Control of Anesthetic State in Non-Human Primates
Chakravarty, S.; Donoghue, J. A.; Waite, A. S.; Mahnke, M.; Garwood, I. C.; Miller, E. K.; Brown, E. N.
10.1101/2021.09.12.459958 — bioengineering — Posted on 2021-09-13
2468 Structured proteins are abundant in unevolved sequence space
Tretyachenko, V.; Vymetal, J.; Neuwirthova, T.; Vondrasek, J.; Fujishima, K.; Hlouchova, K.
10.1101/2021.08.29.458031 — synthetic biology — Posted on 2021-09-13
2469 Genome-wide characterization of the R2R3-MYB transcription factors in pepper (Capsicum spp.) unveils the role of CaMYB101 as repressor in anthocyanin biosynthesis
Liu, Y.; Wu, Y.; Wang, Z.; Zhang, S.; Liu, X.; Tikunov, Y.; Visser, R. G.; Schouten, R. E.; Marcelis, L. F.; Zhang, Z.; Bovy, A.
10.1101/2021.08.24.457473 — plant biology — Posted on 2021-09-13
2471 Lowland plant migrations into alpine ecosystems amplify soil carbon loss under climate warming
Walker, T. W. N.; Gavazov, K.; Guillaume, T.; Lambert, T.; Mariotte, P.; Routh, D.; Signarbieux, C.; Block, S.; Muenkemueller, T.; Nomoto, H.; Crowther, T. W.; Richter, A.; Buttler, A.; Alexander, J. M.
10.1101/2021.07.21.453211 — ecology — Posted on 2021-09-13
2472 Fluctuation of cellular differentiation in limb regeneration is regulated by Pde4b in urodele amphibians
Satoh, A.; Kashimoto, R.; Ohashi, A.; Furukawa, S.; Yamamoto, S.; Inoue, T.; Hayashi, T.; Agata, K.
10.1101/2021.09.13.460030 — developmental biology — Posted on 2021-09-13
2473 p57Kip2 regulates embryonic haematopoietic stem cell numbers by controlling the size of the sympathoadrenal progenitor pool
Kapeni, C.; Nitsche, L.; Kilpatrick, A.; Wilson, N.; Xia, K.; Mirshekar-Syahkal, B.; Malouf, C.; Gottgens, B.; Kirschner, K.; Tomlinson, S.; Ottersbach, K.
10.1101/2021.09.13.459835 — developmental biology — Posted on 2021-09-13
2474 Protein allocation and utilization in the versatile chemolithoautotroph Cupriavidus necator
Jahn, M.; Crang, N.; Janasch, M.; Hober, A.; Forsström, B.; Kimler, K.; Mattausch, A.; Chen, Q.; Asplund-Samuelsson, J.; Hudson, E. P.
10.1101/2021.03.21.436304 — systems biology — Posted on 2021-09-13
2476 Serotonin and common antidepressants regulate lipoprotein(a) macropinocytosis via enhanced cell surface binding
Redpath, G. M. I.; Deo, N.; Siddiqui, H.; Madani, G.; Kapoor-Kaushik, N.; Ariotti, N.; Rutledge, M.; Williams, M.; McCormick, S. P.
10.1101/2021.03.26.437114 — cell biology — Posted on 2021-09-13
2477 Characterization of apicomplexan amino acid transporters (ApiATs) in the malaria parasite Plasmodium falciparum
Wichers, J. S.; van Gelder, C.; Fuchs, G.; Ruge, J. M.; Pietsch, E.; Ferreira, J. L.; Safavi, S.; von Thien, H.; Burda, P.-C.; Mesen-Ramirez, P.; Spielmann, T.; Strauss, J.; Gilberger, T. W.; Bachmann, A.
10.1101/2021.09.08.459553 — molecular biology — Posted on 2021-09-13
2479 Deep protein representations enable recombinant protein expression prediction
Martiny, H.-M.; Armenteros, J. J. A.; Johansen, A. R.; Salomon, J.; Nielsen, H.
10.1101/2021.05.13.443426 — bioinformatics — Posted on 2021-09-13
2481 ILORA: A database of alien vascular flora of India
Pant, V.; Patwardhan, C.; Patil, K.; Bhowmick, A. R.; Mukherjee, A.; Banerjee, A. K.
10.1101/2021.05.28.446252 — ecology — Posted on 2021-09-13
2486 Post-encoding modulation of spatial memory by a GABAA-agonist
Iggena, D.; Maier, P. M.; Haeussler, S. M.; Menk, M.; Olze, H.; Larkum, M. E.; Finke, C.; Ploner, C. J.
10.1101/2021.09.12.458696 — neuroscience — Posted on 2021-09-12
2490 Full-length NLRP3 forms oligomeric cages to mediate NLRP3 sensing and activation
Andreeva, L.; David, L.; Rawson, S.; Shen, C.; Pasricha, T.; Pelegrin, P.; Wu, H.
10.1101/2021.09.12.459968 — immunology — Posted on 2021-09-12
2491 Mice alternate between discrete strategies during perceptual decision-making
Ashwood, Z. C.; Roy, N. A.; Stone, I. R.; International Brain Laboratory, T.; Urai, A. E.; Churchland, A. K.; Pouget, A.; Pillow, J. W.
10.1101/2020.10.19.346353 — neuroscience — Posted on 2021-09-12
2492 The Arabidopsis SAC9 Enzyme defines a cortical population of early endosomes and restricts PI(4,5)P2 to the Plasma Membrane
Doumane, M.; Lebecq, A.; Fangain, A.; Bayle, V.; Rozier, F.; Marques-Bueno, M. d. M.; Boisseau, R.; Simon, M. L. A.; Armengot, L.; Jaillais, Y.; Caillaud, M.-C.
10.1101/2021.09.10.459735 — plant biology — Posted on 2021-09-12
2502 Large ecological benefits of small urban greening actions
Mata, L.; Hahs, A. K.; Palma, E.; Backstrom, A.; King, T.; Olson, A. R.; Renowden, C.; Smith, T. R.; Vogel, B.
10.1101/2021.07.23.453468 — ecology — Posted on 2021-09-12
2503 Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
Zhao, H.; Das, B. K.; Wang, L.; Fujiwara, T.; Zhou, J.; Aykin-Burns, N.; Krager, K. J.; Lan, R.; Mackintosh, S. G.; Edmondson, R.; Jennings, M. L.; Wang, X.; Feng, J. Q.; Barrientos, T.; Gogoi, J.; Kannan, A.; Gao, L.; Xing, W.; Mohan, S.
10.1101/2021.09.12.459964 — cell biology — Posted on 2021-09-12
2504 MKLP2 functions in early mitosis to ensure proper chromosome congression
Schrock, M. S.; Scarberry, L.; Stromberg, B. R.; Sears, C.; Torres, A. E.; Tallman, D.; Krupinski, L.; Chakravarti, A.; Summers, M. K.
10.1101/2021.09.12.459884 — cell biology — Posted on 2021-09-12
2506 mTOR controls neurotoxic lysosome exocytosis in inflammatory reactive astrocytes
Rooney, B.; Leng, K.; McCarthy, F.; Rose, I. V. L.; Herrington, K. A.; Bax, S.; Chin, M. Y.; Fathi, S.; Leonetti, M.; Kao, A. W.; Elias, J. E.; Kampmann, M.
10.1101/2021.09.11.459904 — cell biology — Posted on 2021-09-12
2509 Single-cell metabolite detection and genomics reveals uncultivated talented producer
Kogawa, M.; Miyaoka, R.; Hemmerling, F.; Ando, M.; Yura, K.; Ide, K.; Nishikawa, Y.; Hosokawa, M.; Ise, Y.; Cahn, J. K. B.; Takada, K.; Matsunaga, S.; Mori, T.; Piel, J.; Takeyama, H.
10.1101/2021.09.11.459929 — microbiology — Posted on 2021-09-12
2513 A DROSOPHILA CIRCUIT FOR HABITUATION OVERRIDE
Trisal, S.; Aranha, M. M.; Chodankar, A.; Vijayraghavan, K.; Ramaswami, M.
10.1101/2021.09.11.459900 — neuroscience — Posted on 2021-09-12
2516 Accumulation of auranofin in white adipose tissues lowers leptin levels and exerts anti-diabetic effects
Cox, A. R.; Masschelin, P. M.; Saha, P.; Felix, J. B.; Sharp, R.; Lian, Z.; Xia, Y.; Chernis, N.; Bader, D. A.; Kim, K. H.; Li, X.; Yoshino, J.; Li, X.; Sun, Z.; Wu, H.; Coarfa, C.; Moore, D. D.; Klein, S.; Sun, K.; Hartig, S. M.
10.1101/2021.09.11.459899 — physiology — Posted on 2021-09-12
2517 The polyglutamine amyloid nucleus in living cells is a monomer with competing dimensions of order
Kandola, T.; Venkatesan, S.; Zhang, J.; Lerbakken, B.; Blanck, J. F.; Wu, J.; Unruh, J.; Berry, P.; Lange, J. L.; Von Schulze, A.; Box, A.; Cook, M.; Sagui, C.; Halfmann, R.
10.1101/2021.08.29.458132 — biophysics — Posted on 2021-09-12
2518 MinoTour, real-time monitoring and analysis for Nanopore Sequencers.
Munro, R. J.; Santos, R.; Payne, A.; Forey, T.; Osei, S.; Holmes, N.; Loose, M.
10.1101/2021.09.10.459783 — bioinformatics — Posted on 2021-09-12
2520 Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling
Lim, S.; Boyer, N.; Boo, N.; Huang, C.; Venkatachalam, G.; Juang, Y.-C. A.; Garrigou, M.; Kaan, K.; Peh, K. M.; Sadruddin, A.; Gopal, P.; Duggal, R.; Yuen, T. Y.; Ng, S.; Kannan, S.; Brown, C. J.; Verma, C.; Orth, P.; Peier, A.; Ge, L.; Yu, X.; Bhatt, B.; Chen, F.; Wang, E.; Li, N. J.; Gonzalez, R.; Stoeck, A.; Henry, B.; Sawyer, T. K.; Lane, D. P.; Johannes, C. W.; Biswas, K.; Partridge, A. W.
10.1101/2021.09.11.459913 — biochemistry — Posted on 2021-09-12
2521 Hedgehog signaling can enhance glycolytic ATP production in the Drosophila wing disc
Nellas, I.; Iyer, K. V.; Iglesias-Artola, J. M.; Nadler, A.; Dye, N. A.; Eaton, S.
10.1101/2021.09.11.459911 — developmental biology — Posted on 2021-09-12
2523 Macrophage migration inhibitory factor is a valid drug target at the intersection of herpes simplex virus 1 replication and Alzheimer's disease-relevant cellular pathology
Mueller-Schiffmann, A.; Torres, F.; Kitaygorodskyy, A.; Ramani, A.; Alatza, A.; Tschirner, S.; Prikulis, I.; Yu, S.; Dey, D.; Bader, V.; Rozemuller, A.; Wray, S.; Gopalakrishnan, J.; Riek, R.; Lingappa, V. R.; Korth, C.
10.1101/2021.09.11.459903 — microbiology — Posted on 2021-09-12
2525 Reassortment Network of Influenza A Virus
Gong, X.; Hu, M.; Chen, W.; Yang, H.; Wang, B.; Yue, J.; Jin, Y.; Liang, L.; Ren, H.
10.1101/2021.09.09.459621 — evolutionary biology — Posted on 2021-09-12
2530 Effects of bacterial lipopolysaccharide and Shiga Toxin on induced Pluripotent Stem Cell-derived Mesenchymal Stem Cells
Martire-Greco, D.; La Greca, A.; Castillo Montanez, L.; Biani, C.; Lombardi, A.; Birnberg-Weiss, F.; Norris, A.; Sacerdoti, F.; Amaral, M. M.; Rodrigues-Rodriguez, N.; Pittaluga, J. R.; Furmento, V. A.; Landoni, V. I.; Miriuka, S. G.; Luzzani, C. D.; Fernandez, G. C.
10.1101/2021.09.07.459335 — immunology — Posted on 2021-09-12
2532 Community science designed ribosomes with beneficial phenotypes
Kruger, A.; Watkins, A. M.; Wellington-Oguri, R.; Romano, J.; Kofman, C.; DeFoe, A.; Kim, Y.; Anderson-Lee, J.; Fisker, E.; Townley, J.; Eterna participants, ; d'Aquino, A. E.; Das, R.; Jewett, M. C.
10.1101/2021.09.05.458952 — synthetic biology — Posted on 2021-09-12
2533 Versatile, do-it-yourself, low-cost spinning disk confocal microscope
Halpern, A. R.; Lee, M. Y.; Howard, M. D.; Woodworth, M. A.; Nicovich, P. R.; Vaughan, J. C.
10.1101/2021.09.04.458950 — biophysics — Posted on 2021-09-12
2537 Rescue of stalled clathrin-mediated endocytosis by asymmetric Arp2/3-mediated actin assembly
Jin, M.; Shirazinejad, C.; Wang, B.; Yan, A.; Schöneberg, J.; Upadhyayula, S.; Xu, K.; Drubin, D. G.
10.1101/2021.07.16.452693 — cell biology — Posted on 2021-09-12
2540 Conserved genomic landscapes of differentiation across Populus speciation continuum
Shang, H.; Rendon-Anaya, M.; Paun, O.; Field, D. L.; Hess, J.; Vogl, C.; Liu, J.; Ingvarsson, P. K.; Lexer, C.; Leroy, T.
10.1101/2021.08.26.457771 — evolutionary biology — Posted on 2021-09-12
2541 HypVW is an HOCl-Sensing Two Component System in Escherichia coli
El Hajj, S.; Henry, C.; Vergnes, A.; Loiseau, L.; Gael, B.; Barre, R.; Aussel, L.; Ezraty, B.
10.1101/2021.09.09.459708 — microbiology — Posted on 2021-09-12
2542 Sodium Thiosulfate acts as an H2S mimetic to prevent intimal hyperplasia via inhibition of tubulin polymerization
Macabrey, D.; Longchamp, A.; Macarthur, M.; Lambelet, M.; Urfer, S.; Corpataux, J.-M.; Deglise, S.; ALLAGNAT, F.
10.1101/2021.09.09.459573 — physiology — Posted on 2021-09-12
2543 uPTI: uniaxial permittivity tensor imaging of intrinsic density and anisotropy
Yeh, L.-H.; Ivanov, I. E.; Byrum, J. R.; Chhun, B. B.; Guo, S.-M.; Foltz, C.; Hashemi, E.; Perez-Bermejo, J. A.; Wang, H.; Yu, Y.; Kazansky, P. G.; Conklin, B. R.; Han, M. H.; Mehta, S. B.
10.1101/2020.12.15.422951 — biophysics — Posted on 2021-09-12
2545 Evolutionary innovations through gain and loss of genes in the ectomycorrhizal Boletales
Wu, G.; Miyauchi, S.; Morin, E.; Kuo, A.; Drula, E.; Varga, T.; Kohler, A.; Feng, B.; Cao, Y.; Lipzen, A.; Daum, C.; Hundley, H.; Pangilinan, J.; Johnson, J.; Barry, K. W.; LaButti, K.; Ng, V.; Ahrendt, S.; Min, B.; Choi, I.-G.; Park, H.; Plett, J.; Magnuson, J.; Spatafora, J. W.; Nagy, L.; Henrissat, B.; Grigoriev, I. V.; Yang, Z.-L.; Xu, J.; Martin, F. M.
10.1101/2021.09.09.459636 — genomics — Posted on 2021-09-12
2547 Protein-lipid interaction at low pH induces oligomerisation of the MakA cytotoxin from Vibrio cholerae
Nadeem, A.; Berg, A.; Pace, H.; Alam, A.; Toh, E.; Aden, J.; Zlatkov, N.; Myint, S. L.; Persson, K.; Gröbner, G.; Sjöstedt, A.; Bally, M.; Barandun, J.; Uhlin, B. E.; Wai, S. N.
10.1101/2021.09.10.459761 — cell biology — Posted on 2021-09-12
2548 A Model for DHX15 Mediated Disassembly of A-Complex Spliceosomes
Maul-Newby, H. M.; Amorello, A. N.; Sharma, T.; Kim, J. H.; Modena, M. S.; Prichard, B. E.; Jurica, M. S.
10.1101/2021.09.10.459862 — molecular biology — Posted on 2021-09-12
2551 Respiration, heartbeat, and conscious tactile perception
Grund, M.; Al, E.; Pabst, M.; Dabbagh, A.; Stephani, T.; Nierhaus, T.; Gaebler, M.; Villringer, A.
10.1101/2021.03.22.436396 — neuroscience — Posted on 2021-09-12
2554 Community science designed ribosomes with beneficial phenotypes
Kruger, A.; Watkins, A. M.; Wellington-Oguri, R.; Romano, J.; Kofman, C.; DeFoe, A.; Kim, Y.; Anderson-Lee, J.; Fisker, E.; Townley, J.; Eterna participants, ; d'Aquino, A. E.; Das, R.; Jewett, M. C.
10.1101/2021.09.05.458952 — synthetic biology — Posted on 2021-09-11
2564 Engineering of human mini-bones for the standardized modeling of healthy hematopoiesis, leukemia and solid tumor metastasis
Grigoryan, A.; Zacharaki, D.; Balhuizen, A.; Come, C. R.; Frank, A.-K.; Garcia Garcia, A.; Aaltonen, K.; Manas, A.; Esfandyari, J.; Kalantari, N.; Kjellman, P.; Prithiviraj, S.; Englund, E.; Madsen, C. D.; Porse, B.; Bexell, D.; Bourgine, P. E.
10.1101/2021.09.11.459806 — bioengineering — Posted on 2021-09-11
2567 Genome Assembly of the Roundjaw Bonefish (Albula glossodonta), a Vulnerable Circumtropical Sportfish
Pickett, B. D.; Talma, S.; Glass, J. R.; Ence, D.; Cowley, P. D.; Ridge, P. G.; Kauwe, J. S.
10.1101/2021.09.10.458299 — genomics — Posted on 2021-09-11
2571 Environmental niche and demographic modeling of American chestnut near its southwestern range limit
Laport, R. G.; Brookover, Z. S.; Christman, B. D.; Ng, J.; Philley, K.; Craddock, J. H.
10.1101/2021.09.10.459451 — ecology — Posted on 2021-09-11
2572 Wild pigs mediate far-reaching agricultural impacts on tropical forest soil microbial communities
Brearley, F. Q.; Song, H.; Tripathi, B.; Dong, K.; Mohamad Zin, N.; Abdul Rachman, A. R.; Ickes, K.; Adams, J. M.; Luskin, M. S.
10.1101/2021.09.10.459828 — ecology — Posted on 2021-09-11
2574 Vegetation structure determines cyanobacterial communities during soil development across global biomes
Cano-Diaz, C.; Maestre, F. T.; Wang, J.; Li, J.; Singh, B.; Ochoa, V.; Gozalo, B.; Delgado-Baquerizo, M.
10.1101/2021.09.11.459883 — ecology — Posted on 2021-09-11
2579 A faithful in vivo model of human macrophages in metastatic melanoma
Voillet, V.; Berger, T. R.; McKenna, K. M.; Paulson, K. G.; Smythe, K. S.; Hunter, D. S.; Valente, W. J.; Weaver, S. J.; Campbell, J. S.; Kim, T. S.; Byrd, D. R.; Bielas, J. H.; Pierce, R. H.; Chapuis, A. G.; Gottardo, R.; Rongvaux, A.
10.1101/2021.09.09.459682 — immunology — Posted on 2021-09-11
2580 Deletion of Vhl in Dmp1-expressing cells causes microenvironmental impairment of B cell lymphopoiesis
Chicana, B.; Abbasizadeh, N.; Burns, C.; Taglinao, H.; Spencer, J. A.; Manilay, J. O.
10.1101/2021.09.10.459794 — immunology — Posted on 2021-09-11
2584 Working memory performance is tied to stimulus complexity
Pusch, R.; Packheiser, J.; Azizi, A. H.; Sevincik, C. S.; Rose, J.; Cheng, S.; Stuettgen, M. C.; Guentuerkuen, O.
10.1101/2021.09.10.459776 — neuroscience — Posted on 2021-09-11
2585 An in-vivo validation of ESI methods with focal sources
Pascarella, A.; Mikulan, E.; Sciacchitano, F.; Sarasso, S.; Rubino, A.; Sartori, I.; Cardinale, F.; Zauli, F.; Avanzini, P.; Nobili, L.; Sorrentino, A.
10.1101/2021.09.10.459782 — neuroscience — Posted on 2021-09-11
2586 Behavioral and Neurostructural changes associated with Chronic Amygdala Hyperactivation
Misquitta, K. A.; Codeluppi, S. A.; Knoch, J. K.; Bansal, Y.; Tomoda, T.; Ellegood, J.; Lerch, J. P.; Sibille, E.; Nikolova, Y.; Banasr, M.
10.1101/2021.09.11.459894 — neuroscience — Posted on 2021-09-11
2587 Dense cortical input to the rostromedial tegmental nucleus mediates aversive signaling
Glover, E. J.; Starr, E. M.; Gascon, A.; Clayton-Stiglbauer, K.; Amegashie, C. L.; Selchick, A. H.; Vaughan, D. T.; Wayman, W. N.; Woodward, J. J.; Chandler, L. J.
10.1101/2021.09.10.459663 — neuroscience — Posted on 2021-09-11
2588 Dopamine biases sensitivity to personal goals and social influence in self-control over everyday desires
Castrellon, J. J.; Young, J. S.; Dang, L. C.; Smith, C. T.; Cowan, R. L.; Zald, D. H.; Samanez-Larkin, G. R.
10.1101/2021.09.10.459829 — neuroscience — Posted on 2021-09-11
2593 Horizontal connectivity in V1 : Prediction of coherence in contour and motion integration
Fregnac, Y.; Le Bec, B.; Troncoso, X. G.; Desbois, C.; Passarelli, Y.; Baudot, P.; Monier, C.; Pananceau, M.
10.1101/2021.09.10.459746 — neuroscience — Posted on 2021-09-11
2594 Probing neuropeptide volume transmission in vivo by a novel all-optical approach
Xiong, H.; Lacin, E.; Ouyang, H.; Naik, A.; Xu, X.; Xie, C.; Youn, J.; Kumar, K.; Kern, T.; Aisenberg, E.; Kircher, D.; Li, X.; Zasadzinski, J. A.; Mateo, C.; Kleinfeld, D.; Hrabetova, S.; Slesinger, P.; Qin, Z.
10.1101/2021.09.10.459853 — neuroscience — Posted on 2021-09-11
2597 Combining CRISPR/Cas9 and brain imaging: from genes to proteins to networks
Marciano, S.; Ionescu, T. M.; Saw, R. S.; Cheong, R. Y.; Kirik, D.; Maurer, A.; Pichler, B. J.; Herfert, K.
10.1101/2021.09.10.459766 — neuroscience — Posted on 2021-09-11
2598 High-fat diet feeding reduces the expression of Rab3a, Rab3gap1, and Rab3Gap2 genes that are pivotal to neuronal exocytosis.
Ferrreira, L. A.; Martins, F. V.; Freitas, M. L.; Oliveira, L. R.; Oliveira, L. R.; Castro Junior, C. J.; Jehee, F. S.; Bosco, A. A.; Fernandes, K. S.
10.1101/2021.09.10.459820 — neuroscience — Posted on 2021-09-11
2599 Whole brain mapping of glutamate in adult and old primates at 11.7T
Garin, C. M.; Nadkarni, N. A.; Pepin, J.; Flament, J.; Dhenain, M.
10.1101/2021.09.10.459778 — neuroscience — Posted on 2021-09-11
2603 Effectors from a Bacterial Vector-Borne Pathogen Exhibit Diverse Subcellular Localization, Expression Profiles and Manipulation of Plant Defense
Reyes Caldas, P.; Zhu, J.; Breakspear, A.; Thapa, S. P.; Toruno, T.; Perilla-Henao, L.; Casteel, C.; Faulkner, C.; Coaker, G.
10.1101/2021.09.10.459857 — plant biology — Posted on 2021-09-11
2604 BaRTv2: A highly resolved barley reference transcriptome for accurate transcript-specific RNA-seq quantification
Coulter, M.; Entizne, J. C.; Guo, W.; Bayer, M.; Wonneberger, R.; Milne, L.; Schreiber, M.; Haaning, A.; Muehlbauer, G.; McCallum, N.; Fuller, J.; Simpson, C.; Stein, N.; Brown, J. W.; Waugh, R.; Zhang, R.
10.1101/2021.09.10.459729 — plant biology — Posted on 2021-09-11
2607 Quercetin prevents insulin dysfunction in hypertensive animals
Serra, C. A.; Reis, A. F.; Calsa, B.; Bueno, C. S.; Helaehil, J. V.; de Souza, S. A. R.; Oliveira, C. A.; Vanzela, E. C.; Amaral, M. E.
10.1101/2021.09.10.459841 — physiology — Posted on 2021-09-11
2611 Identification of hub genes and pathways in nonalcoholic steatohepatitis by integrated bioinformatics analysis
Einaliyan, P.; Owfi, A.; Mahmanzar, M.; Aghajanzadeh, T.; Hadizadeh, M.; Sharifi-Zarchi, A.; Hatami, B.; Asadzadeh Aghdaei, H.; Zali, M. R.; Baghaei, K.
10.1101/2021.09.10.459743 — bioinformatics — Posted on 2021-09-11
2612 Characterization of the secretome, transcriptome and proteome of human β cell line EndoC-βH1
Ryaboshapkina, M.; Saitoski, K.; Hamza, G. M.; Jarnuczak, A. F.; Berthault, C.; Sengupta, K.; Underwood, C. R.; Andersson, S.; Scharfmann, R.
10.1101/2021.09.09.459582 — bioinformatics — Posted on 2021-09-11
2614 Benchmarking feature quality assurance strategies for non-targeted metabolomics
El Abiead, Y.; Milford, M.; Schoeny, H.; Rusz, M.; Salek, R. M.; Koellensperger, G.
10.1101/2021.09.09.459600 — bioinformatics — Posted on 2021-09-11
2615 Streamlined use of protein structures in variant analysis
Kaur, S.; Sikta, N.; Schafferhans, A.; Bordin, N.; Cowley, M. J.; Thomas, D. M.; Ballinger, M. L.; O'Donoghue, S. I.
10.1101/2021.09.10.459756 — bioinformatics — Posted on 2021-09-11
2616 iCn3D: from Web-based 3D Viewer to Structure Analysis Tool in Batch Mode
Wang, J.; Youkharibache, P.; Marchler-Bauer, A.; Lanczycki, C.; Zhang, D.; Lu, S.; Madej, T.; Marchler, G. H.; Cheng, T.; Chong, L. C.; Zhao, S.; Yang, K.; Lin, J.; Cheng, Z.; Dunn, R.; Malkaram, S. A.; Tai, C.-H.; Enoma, D.; Busby, B.; Johnson, N.; Tabaro, F.; Song, G.; Ge, Y.
10.1101/2021.09.10.459868 — bioinformatics — Posted on 2021-09-11
2620 How biological cells including platelets and megakaryocytes decide complex problems fast but risky
Prada, J.; Balkenhol, J.; Kaltdorf, M.; Osmanoglu, O.; Stoerkle, M.; Heinze, K.; Manukjan, G.; Schulze, H.; Dandekar, T.
10.1101/2021.09.10.459594 — bioinformatics — Posted on 2021-09-11
2622 An integrated view of baseline protein expression in human tissues
Prakash, A.; Garcia-Seisdedos, D.; Wang, S.; Kundu, D. J.; Collins, A.; George, N.; Moreno, P.; Papathedourou, I.; Jones, A. R.; Vizcaino, J. A.
10.1101/2021.09.10.459811 — bioinformatics — Posted on 2021-09-11
2629 Long-term balancing selection in highly dynamic mating loci generates trans-species polymorphisms in fungi
Peris, D.; Lu, D. S.; Kinneberg, V. B.; Methlie, I.-S. H.; Dahl, M. S.; James, T. Y.; Kauserud, H.; Skrede, I.
10.1101/2021.09.10.459787 — genomics — Posted on 2021-09-11
2634 Social hosts evade predation but have deadlier parasites
Walsman, J. C.; Janecka, M. J.; Clark, D. R.; Kramp, R. D.; Rovenolt, F.; Patrick, R.; Mohammed, R. S.; Konczal, M.; Cressler, C. E.; Stephenson, J. F.
10.1101/2021.09.10.459661 — ecology — Posted on 2021-09-11
2639 The Application of The Skin Virome for Human Identification
Graham, E. H.; Fernando, S.; Clarke, J.; Herr, J. R.; Adamowicz, M.
10.1101/2021.09.10.459834 — microbiology — Posted on 2021-09-11
2640 Induction of transposable element expression is central to innate sensing
Rookhuizen, D. C.; Bonte, P.-E.; Ye, M.; Hoyler, T.; Gentili, M.; Burgdorf, N.; Durand, S.; Apprahamian, F.; Kroemer, G.; Manel, N.; Waterfall, J.; Milne, R.; Goudot, C.; Towers, G. J.; Amigorena, S.
10.1101/2021.09.10.457789 — immunology — Posted on 2021-09-11
2641 Clonal evolution and specificity of the human T follicular helper cell response to Plasmodium falciparum circumsporozoite protein
Wahl, I.; Obraztsova, A.; Puchan, J.; Hundsdorfer, R.; Chakravarty, S.; Sim, K. L.; Hoffman, S. L.; Kremsner, P.; Mordmueller, B.; Wardemann, H.
10.1101/2021.09.10.459751 — immunology — Posted on 2021-09-11
2643 Reproductive neuronal circuitry in adaptive changes of energy balance
Lee, P.; Saenz de Miera, C.; Bellefontaine, N.; Silveira, M. A.; Zampieri, T. T.; Donato, J.; Williams, K. W.; Frazao, R.; Elias, C. F.
10.1101/2021.09.09.459635 — neuroscience — Posted on 2021-09-11
2645 Local neuronal excitation and global inhibition during epileptic fast ripples in humans.
Curot, J.; Barbeau, E. J.; Despouy, E.; Denuelle, M.; Sol, J. C.; Lotterie, J.-A.; Valton, L.; Peyrache, A.
10.1101/2021.09.09.459695 — neuroscience — Posted on 2021-09-11
2654 Chromosome-scale genome assembly of Eustoma grandiflorum, the first complete genome sequence in family Gentianaceae
Shirasawa, K.; Arimoto, R.; Hirakawa, H.; Ishimorai, M.; Ghelfi, A.; Miyasaka, M.; Endo, M.; Kawabata, S.; Isobe, S.
10.1101/2021.09.09.459690 — genomics — Posted on 2021-09-11
2655 Evolutionary innovations through gain and loss of genes in the ectomycorrhizal Boletales
Wu, G.; Miyauchi, S.; Morin, E.; Kuo, A.; Drula, E.; Varga, T.; Kohler, A.; Feng, B.; Cao, Y.; Lipzen, A.; Daum, C.; Hundley, H.; Pangilinan, J.; Johnson, J.; Barry, K. W.; LaButti, K.; Ng, V.; Ahrendt, S.; Min, B.; Choi, I.-G.; Park, H.; Plett, J.; Magnuson, J.; Spatafora, J. W.; Nagy, L.; Henrissat, B.; Grigoriev, I. V.; Yang, Z.-L.; Xu, J.; Martin, F. M.
10.1101/2021.09.09.459636 — genomics — Posted on 2021-09-11
2660 Exosomal MFGE8 from high glucose induced endothelial cells is involved in calcification/senescence of vascular smooth muscle cells
Ni, Y.-Q.; Li, S.; LIn, X.; Wang, Y.-J.; He, J.-Y.; Song, W.-L.; Xiang, Q.-Y.; Zhao, Y.; Li, C.; Wang, Y.; Li, H.-H.; Liang, Z.; Zhan, J.-K.; Liu, Y.-S.
10.1101/2021.09.10.459867 — molecular biology — Posted on 2021-09-11
2662 Even allocation of benefits stabilizes microbial community engaged in metabolic division of labor
Wang, M.; Chen, X.; Liu, x.; Fang, Y.; Zheng, X.; Huang, T.; Tang, Y.-Q.; Nie, Y.; Wu, X.-L.
10.1101/2021.09.10.459869 — microbiology — Posted on 2021-09-11
2664 New auranofin analogs with antibacterial properties against Burkholderia clinical isolates
Maydaniuk, D.; Wu, B.; Truong, D.; Liyanage, S. H.; Hogan, A. M.; Yap, Z. L.; Yan, M.; Cardona, S. T.
10.1101/2021.09.10.459877 — microbiology — Posted on 2021-09-11
2665 A well conserved archaeal B-family polymerase functions as a mismatch and lesion extender
Feng, X.; Zhang, B.; Gao, Z.; Xu, R.; Liu, X.; Ishino, S.; Feng, M.; Shen, Y.; Ishino, Y.; She, Q.
10.1101/2021.09.10.459716 — microbiology — Posted on 2021-09-11
2667 Overriding defective FPR chemotaxis signaling in diabetic neutrophil stimulates infection control in diabetic wound
Roy, R.; Zayas, J.; Wood, S. J.; Mohamed, M. F.; Frausto, D. M.; Estupinian, R.; Giurini, E. F.; Kuzel, T. M.; Zloza, A.; Reiser, J.; Shafikhani, S. H.
10.1101/2021.09.09.459638 — immunology — Posted on 2021-09-11
2668 Single cell multi-omics reveals early elevated function and multiple fates within human progenitor exhausted CD8+ T cells
Luciani, F.; Samir, J.; Leung, P.; Kedzierska, K.; Nguyen, T.; Lloyd, A.; Cai, C.; Bull, R.; Keoshkerian, E.; Eltahla, A.; Peters, T.; Gaudieri, S.; Gupta, M.; Adikari, T.; Louie, R.; Rizzetto, S.; Van der Byl, W.; Rasoli, M.; Palgen, J.-L.
10.1101/2021.09.09.459584 — immunology — Posted on 2021-09-11
2669 Germinal center activity and B cell maturation promote protective antibody responses against Plasmodium pre-erythrocytic infection
Visweswaran, G. R.; Vijayan, K.; Chandrasekaran, R.; Trakhimets, O.; Whiteside, S. L.; Vigdorovich, V.; Yang, A.; Raappana, A.; Watson, A.; Selman, W.; Zuck, M.; Dambrauskas, N.; Kaushansky, A.; Sather, D. N.
10.1101/2021.09.10.459481 — immunology — Posted on 2021-09-11
2670 A modular toolset for electrogenetics
Lawrence, J. M.; Yin, Y.; Bombelli, P.; Scarampi, A.; Storch, M.; Wey, L. T.; Climent-Catala, A.; PixCell iGEM team, ; Baldwin, G. S.; O'Hare, D.; Howe, C. J.; Zhang, J. Z.; Ouldridge, T. E.; Ledesma-Amaro, R.
10.1101/2021.09.10.459750 — synthetic biology — Posted on 2021-09-11
2671 Peroxide antimalarial drugs target redox homeostasis in Plasmodium falciparum infected red blood cells
Siddiqui, G.; Giannangelo, C.; De Paoli, A. E.; Schuh, A. K.; Heimsch, K.; Anderson, D.; Brown, T. G.; MacRaild, C. A.; Wu, J.; Wang, X.; Dong, Y.; Vennerstrom, J. L.; Becker, K.; Creek, D. J.
10.1101/2021.09.10.459878 — pharmacology and toxicology — Posted on 2021-09-11
2674 HOIL-1-catalysed ubiquitylation of unbranched glucosaccharides and its activation by ubiquitin oligomers
Kelsall, I. R.; McCrory, E. H.; Xu, Y.; Scudamore, C. L.; Nanda, S. K.; Mancebo-Gamella, P.; Wood, N. T.; Knebel, A.; Matthews, S. J.; Cohen, P.
10.1101/2021.09.10.459791 — biochemistry — Posted on 2021-09-11
2679 Kif11 overexpression rescues cognition, long-term potentiation, and spine defects in mouse and cell models of Alzheimer's disease
Lucero, E. M.; Freund, R. K.; Johnson, N. R.; Dooling, B.; Sullivan, E.; Prikhodko, O.; Ahmed, M. M.; Dell'Acqua, M. L.; Chial, H. J.; Potter, H.
10.1101/2021.09.09.459627 — neuroscience — Posted on 2021-09-11
2680 Engineered bacteria detect tumor DNA in vivo
Cooper, R. M.; Wright, J. A.; Ng, J. Q.; Goyne, J. M.; Suzuki, N.; Lee, Y. K.; Ichinose, M.; Radford, G.; Thomas, E. M.; Vrbanac, L.; Knight, R.; Woods, S. L.; Worthley, D. L.; Hasty, J.
10.1101/2021.09.10.459858 — synthetic biology — Posted on 2021-09-11
2681 OrBITS: A High-throughput, time-lapse, and label-free drug screening platform for patient-derived 3D organoids
Deben, C.; De La Hoz, E. C.; Le Compte, M.; Van Schil, P.; Hendriks, J. M.; Lauwers, P.; Yogeswaran, S. K.; Lardon, F.; Pauwels, P.; Bogaerts, A.; Smits, E.; Vanlanduit, S.; Lin, A.
10.1101/2021.09.09.459656 — cancer biology — Posted on 2021-09-11
2683 Multi-omic Characterization of Pancreatic Cancer-Associated Macrophage Polarization Reveals Deregulated Metabolic Programs Driven by the GMCSF-PI3K Pathway
Boyer, S. M.; Lee, H.-J.; Steele, N.; Zhang, L.; Sajjakulnukit, P.; Andren, A.; Ward, M. H.; Basrur, V.; Zhang, Y.; Nesvizhskii, A.; Pasca di Magliano, M.; Halbrook, C. J.; Lyssiotis, C. A.
10.1101/2021.09.10.459752 — cancer biology — Posted on 2021-09-11
2684 Deep Learning identifies new morphological patterns of Homologous Recombination Deficiency in luminal breast cancers from whole slide images.
Lazard, T.; Bataillon, G.; Naylor, P.; Popova, T.; Bidard, F.-c.; Stoppa-Lyonnet, D.; Stern, M.-H.; Decenciere, E.; Walter, T.; Salomon, A.
10.1101/2021.09.10.459734 — cancer biology — Posted on 2021-09-11
2687 AlphaFold Protein Structure Database for Sequence-Independent Molecular Replacement
Chai, L.; Zhu, P.; Chai, J.; Pang, C.; Andi, B.; McSweeney, S.; Shanklin, J.; Liu, Q.
10.1101/2021.09.10.459848 — biochemistry — Posted on 2021-09-11
2691 Generation and diversification of recombinant monoclonal antibodies for studying mitosis
DeLuca, K. F.; Mick, J. E.; Hodges, A. L.; Lima, W. C.; Sherman, L.; Schaller, K. L.; Anderson, S. M.; Zhao, N.; Stasevich, T. J.; Varma, D.; Gorbsky, G. J.; Nilsson, J.; DeLuca, J. G.
10.1101/2021.09.10.455288 — cell biology — Posted on 2021-09-11
2693 JAFFAL: Detecting fusion genes with long read transcriptome sequencing
Davidson, N. M.; Chen, Y.; Sadras, T.; Ryland, G. L.; Blombery, P.; Ekert, P. G.; Goeke, J.; Oshlack, A.
10.1101/2021.04.26.441398 — bioinformatics — Posted on 2021-09-11
2694 Metagenomic analysis reveals the signature of gut microbiota associated with human chronotypes
Carasso, S.; Fishman, B.; Stelmach Lask, L.; Shochat, T.; Geva-Zatorsky, N.; Tauber, E.
10.1101/2021.03.16.435653 — genomics — Posted on 2021-09-11
2695 Estimating plasmid conjugation rates: a new computational tool and a critical comparison of methods
Huisman, J. S.; Benz, F.; Duxbury, S. J. N.; de Visser, J. A. G. M.; Hall, A. R.; Fischer, E. A. J.; Bonhoeffer, S.
10.1101/2020.03.09.980862 — microbiology — Posted on 2021-09-11
2698 Engineered small extracellular vesicles as a FGL1/PD-L1 dual-targeting delivery system for alleviating immune rejection
Tsai, H.-i.; Wu, Y.; Liu, X.; Xu, Z.; Liu, L.; Huang, Y.; Wang, L.; Zhang, W.; Zhang, H.; Su, D.; Khan, F. U.; Wang, C.; Eriksson, J. E.; Jia, B.; Cheng, F.; Chen, H.
10.1101/2021.06.14.448282 — bioengineering — Posted on 2021-09-11
2700 Genetic variations within human gained enhancer elements affect human brain sulcal morphology.
Lemaitre, H.; Le Guen, Y.; Tilot, A. K.; Stein, J. L.; Philippe, C.; Mangin, J.-F.; Fisher, S. E.; Frouin, V.
10.1101/2021.09.10.459622 — neuroscience — Posted on 2021-09-11
2701 Combining CRISPR/Cas9 and brain imaging: from genes to proteins to networks
Marciano, S.; Ionescu, T. M.; Saw, R. S.; Cheong, R. Y.; Kirik, D.; Maurer, A.; Pichler, B. J.; Herfert, K.
10.1101/2021.09.10.459766 — neuroscience — Posted on 2021-09-11
2702 Cysteine induces mitochondrial reductive stress in glioblastoma through hydrogen peroxide production
Noch, E. K.; Palma, L.; Yim, I.; Barnett, D.; Walsh, A.; Bhinder, B.; Benedetti, E.; Krumsiek, J.; Gurvitch, J.; Khwaja, S.; Elemento, O.; Cantley, L.
10.1101/2021.09.10.459864 — cancer biology — Posted on 2021-09-11
2703 Human-specific enrichment of schizophrenia risk-genes in callosal neurons of the developing neocortex
Zuccaro, E.; Murek, V.; Kim, K.; Chen, H.-H.; Mancinelli, S.; Oyler-Castrillo, P.; Jimenez Barron, L. T.; Gerhardinger, C.; Brown, J. R.; Byrnes, A.; Neale, B.; Levin, J. Z.; Ziller, M. J.; Lodato, S.; Arlotta, P.
10.1101/2021.09.10.459747 — developmental biology — Posted on 2021-09-11
2704 The language network supports both lexical access and sentence generation during language production
Hu, J.; Small, H.; Kean, H.; Takahashi, A.; Zekelman, L.; Kleinman, D.; Ryan, E.; Ferreira, V.; Fedorenko, E.
10.1101/2021.09.10.459596 — neuroscience — Posted on 2021-09-11
2714 Resolving when (and where) the Thylacine went extinct
Brook, B. W.; Sleightholme, S. R.; Campbell, C. R.; Jaric, I.; Buettel, J. C.
10.1101/2021.01.18.427214 — zoology — Posted on 2021-09-10
2719 Domain adaptive neural networks improvecross-species prediction of transcription factor binding
Cochran, K.; Srivastava, D.; Shrikumar, A.; Balsubramani, A.; Hardison, R. C.; Kundaje, A.; Mahony, S.
10.1101/2021.02.13.431115 — bioinformatics — Posted on 2021-09-10
2721 Improving long-read consensus sequencing accuracy with deep learning
Lal, A.; Brown, M.; Mohan, R.; Daw, J.; Drake, J.; Israeli, J.
10.1101/2021.06.28.450238 — genomics — Posted on 2021-09-10
2722 Modeling miRNA-driven post-transcriptional regulation by using exon-intron split analysis (EISA) in pigs
Marmol-Sanchez, E.; Cirera, S.; Zingaretti, L.; Jacobsen, M. J.; Ramayo-Caldas, Y.; Jorgensen, C. B.; Fredholm, M.; Cardoso, T. F.; Quintanilla, R.; Amills, M.
10.1101/2021.07.14.452370 — genomics — Posted on 2021-09-10
2723 Blm Helicase Facilitates Rapid Replication of Repetitive DNA Sequences in early Drosophila Development
Ruchert, J. M.; Brady, M. M.; McMahan, S.; Lacey, K. J.; Latta, L. C.; Sekelsky, J.; Stoffregen, E. P.
10.1101/2021.06.16.448677 — genetics — Posted on 2021-09-10
2724 Comprehensive analysis of DNA replication timing in genetic diseases and gene knockouts identifies MCM10 as a novel regulator of the replication program
Caballero, M.; Ge, T.; Rebelo, A. R.; Seo, S.; Kim, S.; Brooks, K.; Zuccaro, M. V.; Kanagaraj, R.; Vershkov, D.; Kim, D.; Smogorzewska, A.; Smolka, M. B.; Benvenisty, N.; West, S. C.; Egli, D. C.; Mace, E. M.; Koren, A.
10.1101/2021.09.08.459433 — genetics — Posted on 2021-09-10
2725 N-myc Downstream Regulated Gene 1 (NDRG1) functions as a molecular switch for cellular adaptation to hypoxia
Park, J. S.; Gabel, A. M.; Kang, L.; Canales, B.; Kassir, P.; Osei-Ntansah, A.; Tran, N. D.; Viswanathan, S.; Lee, Y.-S.; Brewster, R.
10.1101/2021.09.10.459675 — developmental biology — Posted on 2021-09-10
2730 Stem cell-derived macrophages as a new platform for studying host-pathogen interactions in livestock
Meek, S.; Watson, T.; Eory, L.; McFarlane, G.; Wynne, F. J.; McCleary, S.; Dunn, L. E. M.; Charlton, E. M.; Craig, C.; Shih, B.; Regan, T.; Taylor, R. M.; Sutherland, L.; Gossner, A.; Chintoan-Uta, C.; Fletcher, S.; Beard, P. M.; Hassan, M. A.; Grey, F.; Hope, J. C.; Stevens, M. P.; Nowak-imialek, M.; Niemann, H.; ROSS, P. J.; Tait-Burkard, C.; Brown, S. M.; Lefevre, L.; Thompson, G.; McColl, B. M.; Lawrence, A. B.; Archibald, A. L.; Steinbach, F.; Crooke, H. R.; Gao, X.; Liu, P.; Burdon, T.
10.1101/2021.09.10.459580 — immunology — Posted on 2021-09-10
2732 Neuronal genetic rescue normalizes brain network dynamics in a lysosomal storage disorder despite persistent storage accumulation
Ahrens-Nicklas, R. C.; Tecedor, L.; Hall, A. F.; Kane, O.; Chung, R. J.; Lysenko, E.; Marsh, E. D.; Davidson, B. L.
10.1101/2021.05.03.442437 — neuroscience — Posted on 2021-09-10
2734 Microtubule-based perception of mechanical conflicts controls plant organ morphogenesis
Stöckle, D.; Reyes-Hernandez, B. J.; Vilches-Barro, A.; Nenadic, M.; Winter, Z.; Marc-Martin, S.; Bald, L.; Ursache, R.; Fujita, S.; Maizel, A.; Vermeer, J.
10.1101/2021.09.09.459674 — plant biology — Posted on 2021-09-10
2735 Molecular basis for the R-type anion channel QUAC1 activity in guard cells
Qin, L.; Tang, L.-h.; Xu, J.-s.; Zhang, X.-h.; Zhu, Y.; Zhang, C.-r.; Liu, X.-l.; Wang, M.-h.; Li, F.; Sun, F.; Su, M.; Zhai, Y.-J.; Chen, Y.-h.
10.1101/2021.09.09.459598 — plant biology — Posted on 2021-09-10
2736 Multiplex knockout of trichome-regulating MYBs in poplar affects light sensitivity and triterpene accumulation
Bewg, W. P.; Harding, S. A.; Engle, N.; Vaidya, B. N.; Yu, J.; Zhou, R.; Reeves, J.; Horn, T. W.; Joshee, N.; Jenkins, J. W.; Shu, S.; Barry, K. W.; Yoshinaga, Y.; Grimwood, J.; Schmitz, R. J.; Schmutz, J.; Tschaplinski, T.; Tsai, C.-J.
10.1101/2021.09.09.459666 — plant biology — Posted on 2021-09-10
2737 Large-scale miRNA-Target Data Analysis to Discover miRNA Co-regulation Network of Abiotic Stress Tolerance in Soybeans
Chang, H.; Zhang, T.; Zhang, H.; Su, L.; Qin, Q.-M.; Li, G.; Li, X.; Wang, L.; Zhao, T.; Zhao, E.; Zhao, H.; Liu, Y.; Stacey, G.; Xu, D.
10.1101/2021.09.09.459645 — plant biology — Posted on 2021-09-10
2738 INTEGUMENT-SPECIFIC TRANSCRIPTIONAL REGULATION IN THE MID- STAGE OF FLAX SEED DEVELOPMENT INFLUENCES THE RELEASE OF MUCILAGE AND THE SEED OIL CONTENT
MIART, F.; Fontaine, J.-X.; Mongelard, G.; Wattier, C.; Lequart, M.; Bouton, S.; Molinie, R.; Dubrulle, N.; Fournet, F.; Demailly, H.; Roulard, R.; Dupont, L.; Boudaoud, A.; Thomasset, B.; Gutierrez, L.; Van Wuytswinkel, O.; Mesnard, F.; Pageau, K.
10.1101/2021.09.09.459608 — plant biology — Posted on 2021-09-10
2739 Principles of resilient coding for plant ecophysiologists
Stinziano, J. R.; Roback, C.; Gamble, D.; Murphy, B. K.; Hudson, P. J.; Muir, C. D.
10.1101/2020.09.11.293530 — plant biology — Posted on 2021-09-10
2741 Subclonal evolution and expansion of THY1-positive cells is associated with recurrence in glioblastoma
Al-Holou, W. N.; Wang, H.; Ravikumar, V.; Oneka, M.; Verhaak, R.; Kim, H.; Pratt, D.; Camelo-Piragua, S.; Speers, C.; Hollon, T.; Sagher, O.; Heth, J.; Muraszko, K.; Lawrence, T. S.; de Carvalho, A.; Mikkelsen, T.; Rao, A.; Rehemtulla, A.
10.1101/2021.09.10.459454 — cancer biology — Posted on 2021-09-10
2742 Rapid, multianalyte detection of opioid metabolites in wastewater
Kumar, N.; Rana, M.; Geiwitz, M.; Khan, N. I.; Catalano, M.; Ortiz-Marquez, J. C.; Kitadai, H.; Weber, A.; Dweik, B.; Ling, X.; van Opijnen, T.; Argun, A.; Burch, K. S.
10.1101/2021.09.09.459680 — biophysics — Posted on 2021-09-10
2745 Whole-genome sequencing analysis reveals the population history of Mus musculus in Madagascar
Fujiwara, K.; Ranorosoa, M. C.; Ohdachi, S. D.; Arai, S.; Sakuma, Y.; Suzuki, H.; Osada, N.
10.1101/2021.09.10.459745 — genetics — Posted on 2021-09-10
2751 Clinical grade ACE2 as a universal agent to block SARS-CoV-2 variants
Wirnsberger, G.; Monteil, V.; Eaton, B.; Postnikova, E.; Murphy, M.; Braunsfeld, B.; Crozier, I.; Kricek, F.; Niederhoefer, J.; Schwarzboeck, A.; Breid, H.; Sanchez Jimenez, A.; Bugajska-Schretter, A.; Dohnal, A.; Ruf, C.; Gugenberger, R.; Hagelkrueys, A.; Montserrat, N.; Holbrook, M.; Oostenbrink, C.; Shoemaker, R. H.; Mirazimi, A.; Penninger, J. M.
10.1101/2021.09.10.459744 — molecular biology — Posted on 2021-09-10
2753 Spexin modulates molecular thermogenic profile of adipose tissue and thermoregulatory behaviors
Sherman, S.; Gupta, N.; Harberson, M.; Powers, R.; Rashleigh, R.; Talla, R.; Thusu, A.; Hill, J. W.
10.1101/2021.09.10.456868 — molecular biology — Posted on 2021-09-10
2754 Pharmacological perturbation of intracellular dynamics as a SARS-CoV-2 antiviral strategy
Bakhache, W.; Partiot, E.; Lucansky, V.; Bare, Y.; Bonaventure, B.; Goujon, C.; Bories, C.; Deffieu, M. S.; Gaudin, R.
10.1101/2021.09.10.459410 — microbiology — Posted on 2021-09-10
2755 Comparative genomic analysis of skin and soft tissue Streptococcus pyogenes isolates from low- and high-income settings
Bah, S. Y.; Keeley, A. J.; Armitage, E. P.; Khalid, H.; Chaudhuri, R. R.; Senghore, E.; Manneh, J.; Tilley, L.; Marks, M.; Darboe, S.; Sesay, A. K.; de Silva, T. I.; Turner, C. E.; The MRCG StrepA Study Group,
10.1101/2021.09.10.459590 — microbiology — Posted on 2021-09-10
2756 An inactivated multivalent influenza A virus vaccine is broadly protective in mice and ferrets
Park, J.; Fong, S.; Schwartzman, L. M.; Sheng, Z.-M.; Freeman, A.; Matthews, L.; Xiao, Y.; Ramuta, M. D.; Batchenkova, N. A.; Qi, L.; Rosas, L. A.; Williams, S.; Scherler, K.; Gouzoulis, M.; Bellayr, I.; Morens, D. M.; Walters, K.-A.; Memoli, M. J.; Kash, J. C.; Taubenberger, J. K.
10.1101/2021.09.10.459807 — microbiology — Posted on 2021-09-10
2757 Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family
Stogios, P. J.; Bordeleau, E.; Xu, Z.; Skarina, T.; Evdokimova, E.; Chou, S.; Luke, D.-T.; D'Souza, A.; Patel, S.; Dantas, G.; Wright, G.; Savchenko, A.
10.1101/2021.09.10.459797 — microbiology — Posted on 2021-09-10
2760 Intranasal administration of a VLP-based vaccine against COVID-19 induces neutralizing antibodies against SARS-CoV-2 and Variants of Concerns
Rothen, D. A.; Krenger, P. S.; Nonic, A.; Balke, I.; Vogt, A.-C.; Chang, X.; Manenti, A.; Vedovi, F.; Resevica, G.; Walton, S.; Zeltins, A.; Montomoli, E.; Vogel, M.; Bachmann, M. F.; Mohsen, M. O.
10.1101/2021.09.10.459749 — immunology — Posted on 2021-09-10
2761 Not so local: the population genetics of convergent adaptation in maize and teosinte.
Tittes, S.; Lorant, A.; McGinty, S.; Doebley, J. F.; Holland, J. B.; Sanchez-Gonzalez, J. d. J.; Seetharam, A. S.; Tenaillon, M. I.; Ross-Ibarra, J.
10.1101/2021.09.09.459637 — evolutionary biology — Posted on 2021-09-10
2762 The architecture and operating mechanism of a cnidarian stinging organelle
Karabulut, A.; McClain, M.; Rubinstein, B.; McKinney, S. A.; Gibson, M.
10.1101/2021.09.09.459669 — cell biology — Posted on 2021-09-10
2763 AgRP neurons coordinate the mitigation of activity-based anorexia
Sutton, A. K.; Duane, S. C.; Shamma, A. M.; Skillings, A.; Krashes, M. J.
10.1101/2021.09.10.459764 — neuroscience — Posted on 2021-09-10
2764 FIBCD1 is a Conserved Receptor for Chondroitin Sulphate Proteoglycans of the Brain Extracellular Matrix and a Candidate Gene for a Complex Neurodevelopmental Disorder
Fell, C. W.; Hagelkruys, A.; Cicvaric, A.; Horrer, M.; Liu, L.; Li, J. S. S.; Stadlmann, J.; Polyansky, A. A.; Mereiter, S.; Tejada, M. A.; Kokotovic, T.; Scaramuzza, A.; Twyman, K.; Morrow, M. M.; Juusola, J.; Yan, H.; Wang, J.; Burmeister, M.; Andersen, T. L.; Wirnsberger, G.; Holmskov, U.; Perrimon, N.; Zagrovic, B.; Monje, F. J.; Moeller, J. B.; Penninger, J. M.; Nagy, V.
10.1101/2021.09.09.459581 — neuroscience — Posted on 2021-09-10
2765 Antigen-derived peptides directly engage the unfolded-protein sensor IRE1α to curb cross-presentation by dendritic cells
Guttman, O.; Le Thomas, A.; Marsters, S. A.; Lawrence, D. A.; Gutgesell, L.; Harnoss, J. M.; Haag, S. M.; Murthy, A.; Strasser, G.; Modrusan, Z.; Wu, T.; Mellman, I.; Ashkenazi, A.
10.1101/2021.09.10.459738 — cell biology — Posted on 2021-09-10
2766 Differential antibody dynamics to SARS-CoV-2 infection and vaccination
Chen, Y.; Tong, P.; Whiteman, N. B.; Moghaddam, A. S.; Zuiani, A.; Habibi, S.; Gautam, A.; Xiao, T.; Cai, Y.; Chen, B.; Wesemann, D. R.
10.1101/2021.09.09.459504 — immunology — Posted on 2021-09-10
2767 Computational drug repurposing against SARS-CoV-2 reveals plasma membrane cholesterol depletion as key factor of antiviral drug activity
Barsi, S.; Papp, H.; Valdeolivas Urbelz, A.; Toth, D. J.; Kuczmog, A.; Madai, M.; Hunyady, L.; Varnai, P.; Saez-Rodriguez, J.; Jakab, F.; Szalai, B.
10.1101/2021.09.10.459786 — systems biology — Posted on 2021-09-10
2768 Targeting the Cx26/NANOG/Focal Adhesion Kinase Complex via Cell Penetrating Peptides in Triple Negative Breast Cancers
Esakov, E.; Mulkearns-Hubert, E. E.; Bharti, R.; Johnson, S.; Bandyopadhyay, S.; Downs-Kelly, E.; Lathia, J.; Reizes, O.
10.1101/2021.09.09.459689 — cancer biology — Posted on 2021-09-10
2769 Active growth signalling promotes cancer cell sensitivity to the CDK7 inhibitor ICEC0942
Wilson, G.; Sava, G.; Vuina, K.; Huard, C.; Meneguello, L.; Coulombe-Huntington, J.; Bertomeu, T.; Maizels, R.; Lauring, J.; Tyers, M.; Ali, S.; Bertoli, C.; de Bruin, R. A. M.
10.1101/2021.09.10.459733 — cancer biology — Posted on 2021-09-10
2771 pH-dependent polymorphism of the structure of SARS-CoV-2 nsp7
Lee, Y.; Tonelli, M.; Rahimi, M.; Anderson, T. K.; Kirchdoerfer, R. N.; Henzler-Wildman, K.; Lee, W.
10.1101/2021.09.10.459800 — biochemistry — Posted on 2021-09-10
2776 Genetic variation in ALDH4A1 predicts muscle health over the lifespan and across species
Villa, O.; Stuhr, N.; Yen, C.-A.; Crimmins, E.; Arpawong, T. E.; Curran, S. P.
10.1101/2021.09.08.459547 — genetics — Posted on 2021-09-10
2779 Long-term persistence of viral RNA and inflammation in the CNS of macaques exposed to aerosolized Venezuelan equine encephalitis virus.
Ma, H.; Albe, J.; Gilliland, T.; McMillen, C.; Gardner, C.; Boyles, D.; Cottle, E.; Dunn, M.; Lundy, J.; Salama, N.; O'Malley, K.; Pandrea, I.; Teichert, T.; Barrick, S.; Klimstra, W.; Hartman, A.; Reed, D. S.
10.1101/2021.09.09.459565 — immunology — Posted on 2021-09-10
2783 Object manifold geometry across the mouse cortical visual hierarchy
Froudarakis, E.; Cohen, U.; Diamantaki, M.; Walker, E. Y.; Reimer, J.; Berens, P.; Sompolinsky, H.; Tolias, A. S.
10.1101/2020.08.20.258798 — neuroscience — Posted on 2021-09-10
2791 Transcriptomic-based quantification of the epithelial-hybrid-mesenchymal spectrum across biological contexts
Mandal, S.; Tejaswi, T.; Janivara, R.; Srikrishnan, S.; Thakur, P.; Sahoo, S.; Chakraborty, P.; Sohal, S. S.; Levine, H.; George, J. T.; Jolly, M. K.
10.1101/2021.09.09.458982 — bioinformatics — Posted on 2021-09-10
2793 Mechanical and possible auxetic properties of human Achilles tendon during in vitro testing to failure
Nagelli, C. V.; Hooke, A.; Quirk, N.; Lopez De Padilla, C.; Hewett, T. E.; van Griensven, M.; Coenen, M.; Berglund, L.; Evans, C. H.; Mueller, S.
10.1101/2021.09.09.459526 — bioengineering — Posted on 2021-09-10
2795 OpenMonkeyChallenge: Dataset and Benchmark Challenges for Pose Tracking of Non-human Primates
Yao, Y.; Abhiraj Mohan, A.; Bliss-Moreau, E.; Coleman, K.; Freeman, S. M.; Machado, C. J.; Raper, J.; Zimmermann, J.; Hayden, B. Y.; Park, H. S.
10.1101/2021.09.08.459549 — animal behavior and cognition — Posted on 2021-09-10
2796 Benchmarking of a Bayesian single cell RNAseq differential gene expression test for dose-response study designs.
Nault, R.; Saha, S.; Bhattacharya, S.; Dodson, J. P.; Sinha, S.; Maiti, T.; Zacharewski, T. R.
10.1101/2021.09.08.459475 — genomics — Posted on 2021-09-10
2802 Kinetochore-mediated microtubule assembly and Augmin-dependent amplification drive k-fiber maturation in mammals
Almeida, A. C.; Oliveira, J.; Drpic, D.; Cheeseman, L.; Damas, J.; Lewin, H. A.; Larkin, D.; Aguiar, P.; Pereira, A. J.; Maiato, H.
10.1101/2021.08.18.456780 — cell biology — Posted on 2021-09-10
2803 Re-evaluating the role of nucleosomal bivalency in early development
Shah, R. N.; Grzybowski, A. T.; Elias, J.; Chen, Z.; Hattori, T.; Lechner, C. C.; Lewis, P. W.; Koide, S.; Fierz, B.; Ruthenburg, A. J.
10.1101/2021.09.09.458948 — molecular biology — Posted on 2021-09-10
2805 Trypanosomal variant surface glycoprotein expression in human African trypanosomiasis patients
So, J.; Sudlow, S.; Sayeed, A.; Grudda, T.; Deborggraeve, S.; Ngoyi, D. M.; Desamber, D. K.; Wickstead, B.; Lejon, V.; Mugnier, M. R.
10.1101/2021.09.09.459620 — microbiology — Posted on 2021-09-10
2806 SARS-CoV-2 Spike Affinity and Dynamics Exclude the Strict Requirement of an Intermediate Host
Castelli, M.; Scietti, L.; Clementi, N.; Cavallaro, M.; Faravelli, S.; Pinnola, A.; Criscuolo, E.; Diotti, R. A.; Clementi, M.; Forneris, F.; Mancini, N.
10.1101/2021.08.11.455960 — microbiology — Posted on 2021-09-10
2807 A HYPOMETABOLIC DEFENSE STRATEGY AGAINST PLASMODIUM INFECTION
Ramos, S.; Ademolue, T. W.; Jentho, E.; Wu, Q.; Guerra, J.; Martins, R.; Pires, G.; Weis, S.; Carlos, A. R.; Mahu, I.; Seixas, E.; Duarte, D.; Rajas, F.; Cardoso, S.; Sousa, A. G.; Lilue, J.; Mithieux, G.; Nogueira, F.; Soares, M. P.
10.1101/2021.09.08.459402 — immunology — Posted on 2021-09-10
2809 Pathogenic neutrophilia drives acute respiratory distress syndrome in severe COVID-19 patients
Eddins, D. J.; Yang, J.; Kosters, A.; Giacalone, V.; Pechuan, X.; Chandler, J. D.; Eum, J.; Babcock, B. R.; Dobosh, B. S.; Hernandez, M. R.; Abdulkhader, F.; Collins, G. L.; Ramonell, R. P.; Moussion, C.; Orlova, D.; Sanz, I.; Lee, F. E.-H.; Tirouvanziam, R.; Ghosn, E.
10.1101/2021.06.02.446468 — immunology — Posted on 2021-09-10
2811 Vestibular CCK neurons drive motion-induced malaise
Machuca-Marquez, P.; Sanchez-Benito, L.; Menardy, F.; Urpi, A.; Appiah, I.; Palmiter, R.; Sanz, E.; Quintana, A.
10.1101/2021.09.08.459510 — neuroscience — Posted on 2021-09-10
2812 Cortical dopamine reduces the impact of motivational biases governing automated behaviour
Scholz, V.; Hook, R. W.; Rostami Kandroodi, M.; Algermissen, J.; Ioannidis, K.; Christmas, D.; Valle, S.; Robbins, T. W.; Grant, J. E.; Chamberlain, S. R.; den Ouden, H. E. M.
10.1101/2021.09.09.459267 — neuroscience — Posted on 2021-09-10
2814 Prediction and action in cortical pain processing
Koppel, L.; Novembre, G.; Kämpe, R.; Savallampi, M.; Morrison, I.
10.1101/2021.09.09.459455 — neuroscience — Posted on 2021-09-10
2815 Strong and specific connections between retinal axon mosaics and midbrain neurons revealed by large scale paired recordings
Sibille, J.; Gehr, C.; Benichov, J. I.; Balasubramanian, H.; Teh, K. L.; Lupashina, T.; Vallentin, D.; Kremkow, J.
10.1101/2021.09.09.459396 — neuroscience — Posted on 2021-09-10
2817 A flow-based latent state generative model of neural population responses to natural images
Bashiri, M.; Walker, E. Y.; Lurz, K.-K.; Jagadish, A. K.; Muhammad, T.; Ding, Z.; Ding, Z.; Tolias, A. S.; Sinz, F. H.
10.1101/2021.09.09.459570 — neuroscience — Posted on 2021-09-10
2820 Spatio-temporal coordination at the maternal-fetal interface promotes trophoblast invasion and vascular remodeling in the first half of human pregnancy
Greenbaum, S.; Averbukh, I.; Soon, E.; Rizzuto, G.; Baranski, A.; Greenwald, N.; Bosse, M.; Jaswa, E. G.; Khair, Z.; Kwok, S.; Warshawsky, S.; Miller, G.; Schwartz, M.; Graf, W.; Van Valen, D.; Keren, L.; Hollmann, T.; van de Rijn, M.; Angelo, M.
10.1101/2021.09.08.459490 — systems biology — Posted on 2021-09-10
2821 Weight Pulling: A Novel Mouse Model of Human Progressive Resistance Exercise
Zhu, W. G.; Hibbert, J. E.; Lin, K. H.; Steinert, N. D.; Lemens, J. L.; Jorgenson, K. W.; Newman, S. M.; Lamming, D. W.; Hornberger, T. A.
10.1101/2021.09.09.458387 — physiology — Posted on 2021-09-10
2823 Polysorbate 80 Controls Morphology, Structure and Stability of Human Insulin Amyloid-Like Spherulites
Zhou, X.; Galparsoro, D. F.; Madsen, A. O.; Vetri, V.; van de Weert, M.; Nielsen, H. M.; Fodera, V.
10.1101/2021.08.10.455855 — biophysics — Posted on 2021-09-10
2825 HTSplotter: an end-to-end data processing, analysis and visualisation tool for chemical and genetic in vitro perturbation screening
Nunes, C.; Anckaert, J.; De Vloed, F.; De Wyn, J.; Durinck, K.; Vandesompele, J.; Speleman, F.; Vermeirssen, V.
10.1101/2021.09.06.459128 — bioinformatics — Posted on 2021-09-10
2826 Plotgardener: Cultivating precise multi-panel figures in R
Kramer, N. E.; Davis, E. S.; Wenger, C. D.; Deoudes, E. M.; Parker, S. M.; Love, M. I.; Phanstiel, D. H.
10.1101/2021.09.08.459338 — bioinformatics — Posted on 2021-09-10
2829 Proteasome complexes experience profound structural and functional rearrangements throughout mammalian spermatogenesis
Zivkovic, D.; Sanchez Dafun, A.; Menneteau, T.; Schahl, A.; Lise, S.; Kervarrec, C.; Toste-Rego, A.; da Fonseca, P.; Chavent, M.; Pineau, C.; Schiltz, O.; Marcoux, J.; Bousquet, M.-P.
10.1101/2021.06.18.447862 — biochemistry — Posted on 2021-09-10
2830 APOK3, a pollen killer antidote in Arabidopsis thaliana
Simon, M.; Durand, S.; Ricou, A.; Vrielynck, N.; Mayjonade, B.; Gouzy, J.; Boyer, R.; Roux, F.; Camilleri, C.; Budar, F.
10.1101/2021.09.08.459474 — genetics — Posted on 2021-09-10
2832 Biomorphogenic feedbacks and the spatial organisation of a dominant grass steer dune development
Bonte, D.; Batsleer, F.; Provoost, S.; Reijers, V.; Vandegehuchte, M. L.; Van De Walle, R.; Dan, S.; Matheve, H.; Rauwoens, P.; Strypsteen, G.; Suzuki, T.; Verwaest, T.; Hillaert, J.
10.1101/2021.08.02.454713 — ecology — Posted on 2021-09-10
2833 Myosin-1b interacts with UNC45A and controls intestinal epithelial morphogenesis
Revenu des Courtils, C.; Parlato, M.; Rosello, M.; Duroure, K.; Duclaux-Loras, R.; Nicolle, O.; Prosperi, M.-T.; Stoufflet, J.; Vougny, J.; Lebreton, C.; Lepine, P.; Michaux, G.; Cerf-Benssusan, N.; Coudrier, E.; Del Bene, F.
10.1101/2021.09.09.459609 — developmental biology — Posted on 2021-09-10
2834 Myogenin controls via AKAP6 non-centrosomal microtubule organizing center formation at the nuclear envelope
Becker, R.; Vergarajauregui, S.; Billing, F.; Sharkova, M.; Lippolis, E.; Mamchaoui, K.; Ferrazzi, F.; Engel, F.
10.1101/2020.12.11.421263 — cell biology — Posted on 2021-09-10
2835 Increasing triacylglycerides and lipid storage by unsaturated lipids protects renal proximal tubules
Perez-Marti, A.; Ramakrishnan, S.; Li, J.; Dugourd, A.; Molenaar, M. R.; De La Motte, L. R.; Grand, K.; Mansouri, A.; Parisot, M.; Lienkamp, S. S.; Saez-Rodriguez, J.; Simons, M.
10.1101/2021.09.07.459360 — cell biology — Posted on 2021-09-10
2836 Characterization of apicomplexan amino acid transporters (ApiATs) in the malaria parasite Plasmodium falciparum
Wichers, J. S.; van Gelder, C.; Fuchs, G.; Ruge, J. M.; Pietsch, E.; Ferreira, J. L.; Safavi, S.; von Thien, H.; Burda, P.-C.; Mesen-Ramirez, P.; Spielmann, T.; Strauss, J.; Gilberger, T. W.; Bachmann, A.
10.1101/2021.09.08.459553 — molecular biology — Posted on 2021-09-10
2837 Identification of a stereotypic molecular arrangement of glycine receptors at native spinal cord synapses
Maynard, S. A.; Rostaing, P.; Gemin, O.; Candat, A.; Dumoulin, A.; Schaefer, N.; Villmann, C.; Triller, A.; Specht, C. G.
10.1101/2021.09.09.459599 — molecular biology — Posted on 2021-09-10
2840 Sex Differences in Cerebral Edema after Experimental Traumatic Brain Injury
Minchew, H. M.; Christian, S. K.; Keselman, P.; Hu, J.; Andrews, B. T.; Harris, J. L.
10.1101/2021.06.25.449932 — neuroscience — Posted on 2021-09-10
2844 Fission stories: Using PomBase to understand Schizosaccharomyces pombe biology
Harris, M. A.; Rutherford, K. M.; Hayles, J.; Lock, A.; Bähler, J.; Oliver, S. G.; Mata, J.; Wood, V.
10.1101/2021.09.07.459264 — bioinformatics — Posted on 2021-09-10
2846 BCN057, a Modulator of GSK3β Induces KRAS G12D Mutant Pancreatic Cancer Cell Death
Singer, E. M.; Chugh, R. M.; Bhanja, P.; Gomez, A.; Gao, L.; Whitelegge, J. P.; McBride, W. H.; Saha, S.; Norris, A. J.
10.1101/2021.09.03.458938 — cancer biology — Posted on 2021-09-10
2847 Vectofusin-1 based T-cell transduction approach for generating murine chimeric antigen receptor T-cells for cancer.
Patel, R.; Devashish, K.; Singh, S.; Nath, P. R.; Gohel, D. M.; Prasad, R.; Singh, M.; Saini, N. Y.
10.1101/2021.08.28.458011 — genetics — Posted on 2021-09-10
2848 A systematic analysis of diet-induced nephroprotection reveals overlapping and conserved changes in cysteine catabolism
Koehler, F. C.; Fu, C.-Y.; Spaeth, M. R.; Hoyer-Allo, K. J. R.; Bohl, K.; Goebel, H.; Lackmann, J.-W.; Grundmann, F.; Osterholt, T.; Gloistein, C.; Steiner, J. D.; Antebi, A.; Benzing, T.; Schermer, B.; Schwarz, G.; Burst, V.; Mueller, R.-U.
10.1101/2021.09.08.459468 — biochemistry — Posted on 2021-09-10
2849 Insights into Mus musculus subspecies population structure across Eurasia revealed by whole-genome sequence analysis
Fujiwara, K.; Kawai, Y.; Moriwaki, K.; Takada, T.; Shiroishi, T.; Saitou, N.; Suzuki, H.; Osada, N.
10.1101/2021.02.05.429881 — genomics — Posted on 2021-09-10
2850 Identification of the three zinc-binding sites on Tau protein
La Rocca, R.; Tsvetkov, P. O.; Golovin, A. V.; Allegro, D.; Barbier, P.; Soazig, M.; Guerlesquin, F.; Devred, F.
10.1101/2021.04.23.441079 — molecular biology — Posted on 2021-09-10
2856 Effects of age and surface instability on the control of the center of mass
van den Bogaart, M.; Bruijn, S. M.; Spildooren, J.; van Dieën, J. H.; Meyns, P.
10.1101/2021.09.08.459390 — bioengineering — Posted on 2021-09-10
2857 Mechanism of Tripeptide Trimming by γ-Secretase
Bhattarai, A.; Devkota, S.; Do, H. N.; Wang, J.; Bhattarai, S.; Wolfe, M. S.; Miao, Y.
10.1101/2021.08.05.455243 — biochemistry — Posted on 2021-09-10
2858 Genetic, epigenetic, and environmental mechanisms govern allele-specific gene expression
St. Pierre, C. L.; Macias-Velasco, J. F.; Wayhart, J. P.; Yin, L.; Semenkovich, C. F.; Lawson, H.
10.1101/2021.09.09.459642 — genomics — Posted on 2021-09-10
2861 Single-nucleus transcriptomic analyses reveal microglial activation underlying cerebellar degeneration in Ataxia Telangiectasia
Lai, J.; Kim, J.; Jeffries, A. M.; Tolles, A.; Chittenden, T. W.; Buckley, P. G.; Yu, T. W.; Lodato, M. A.; Lee, E. A.
10.1101/2021.09.09.459619 — neuroscience — Posted on 2021-09-09
2864 Osteoblast-osteoclast co-cultures: a systematic review and map of available literature
Remmers, S. J. A.; de Wildt, B. W. M.; Vis, M. A. M.; Spaander, E. S. R.; de Vries, R. B. M.; Ito, K.; Hofmann, S.
10.1101/2021.09.09.459671 — cell biology — Posted on 2021-09-09
2866 Spinal reconsolidation engages non-ionotropic NMDA receptor signaling to reverse pain hypersensitivity
D'Souza, A. J.; Rodriguez-Hernandez, D.; Zhang, H.; He, D.; Zain, M.; Fung, S.; Bennett, L. A.; Bonin, R. P.
10.1101/2021.09.08.458120 — neuroscience — Posted on 2021-09-09
2867 Methylothon: a versatile course-based high school research experience in microbiology and bioinformatics-- with pink bacteria
Jones, P. A.; Frischer, D.; Mueller, S.; Le, T.; Schwanes, A.; Govindaraju, A.; Shalvarjian, K. E.; Leducq, J.-B.; Marx, C. J.; Martinez-Gomez, N. C.; Lee, J. A.
10.1101/2021.09.08.459370 — scientific communication and education — Posted on 2021-09-09
2868 A global dataset for the projected impacts of climate change on four major crops
Hasegawa, T.; Wakatsuki, H.; Ju, H.; Vyas, S.; Nelson, G. C.; Farrell, A.; Deryng, D.; Meza, F.; Makowski, D.
10.1101/2021.05.27.444762 — plant biology — Posted on 2021-09-09
2869 Cell-type specific circadian bioluminescence rhythms in Dbp reporter mice
Smith, C. B.; van der Vinne, V.; McCartney, E.; Stowie, A. C.; Leise, T. L.; Martin-Burgos, B.; Molyneux, P. C.; Garbutt, L. A.; Brodsky, M. H.; Davidson, A. J.; Harrington, M. E.; Dallmann, R.; Weaver, D. R.
10.1101/2021.04.04.438413 — physiology — Posted on 2021-09-09
2871 Non-Newtonian Blood Rheology Impacts Left Atrial Stasis in Patient-Specific Simulations
Gonzalo, A.; Garcia-Villalba, M.; Rossini, L.; Duran, E.; Vigneault, D.; Martinez-Legazpi, P.; Flores, O.; Bermejo, J.; McVeigh, E.; Kahn, A.; del Alamo, J. C.
10.1101/2021.06.24.449801 — bioengineering — Posted on 2021-09-09
2872 The genome of the endangered Macadamia jansenii displays little diversity but represents an 1 important genetic resource for plant breeding
Sharma, P.; Murigneux, V.; Haimovitz, J.; Nock, C.; Tian, W.; Kharabian Masouleh, A.; Topp, B.; Alam, M.; Furtado, A.; Henry, R.
10.1101/2021.09.08.459545 — genomics — Posted on 2021-09-09
2874 Population genomics of Cryptosporidium hominis across five continents identifies two subspecies that have diverged and recombined during 500 years of evolution
Tichkule, S.; Caccio, S. M.; Robinson, G.; Chalmers, R. M.; Mueller, I.; Emery-Corbin, S. J.; Eibach, D.; Tyler, K. M.; van Oosterhout, C.; Jex, A.
10.1101/2021.09.09.459610 — genomics — Posted on 2021-09-09
2875 Barcoded bulk QTL mapping reveals highly polygenic and epistatic architecture of complex traits in yeast
Ba, A. N. N.; Lawrence, K. R.; Rego-Costa, A.; Gopalakrishnan, S.; Temko, D.; Michor, F.; Desai, M. M.
10.1101/2021.09.08.459513 — genetics — Posted on 2021-09-09
2880 Bma-LAD-2, an intestinal cell adhesion protein, as a potential therapeutic target for lymphatic filariasis
Flynn, A. F.; Taylor, R. T.; Pazgier, M. E.; Bennuru, S.; Lindrose, A. R.; Sterling, S. L.; Morris, C. P.; Maugel, T. K.; Nutman, T. B.; Mitre, E.
10.1101/2021.09.09.459564 — microbiology — Posted on 2021-09-09
2882 The VarA-CsrA regulatory pathway influences cell shape in Vibrio cholerae
Lemos Rocha, L. F.; Peters, K.; Depelteau, J. S.; Briegel, A.; Vollmer, W.; Blokesch, M.
10.1101/2021.09.09.459595 — microbiology — Posted on 2021-09-09
2883 Adolescent development of multiscale structural wiring and functional interactions in the human connectome
Park, B.-y.; Paquola, C.; Bethlehem, R. A. I.; Benkarim, O.; Neuroscience in Psychiatry Network (NSPN) Consortium, ; Misic, B.; Smallwood, J.; Bullmore, E. T.; Bernhardt, B.
10.1101/2021.08.16.456455 — neuroscience — Posted on 2021-09-09
2887 Investigation of gating in outer membrane porins provides new perspectives on antibiotic resistance mechanisms
Vasan, A. K.; Haloi, N.; Ulrich, R. J.; Metcalf, M. E.; Wen, P.-C.; Metcalf, W. W.; Hergenrother, P. J.; Shukla, D.; Tajkhorshid, E.
10.1101/2021.09.09.459668 — biophysics — Posted on 2021-09-09
2892 Abnormal Differentiation and Proliferation of Coronary Arterial Endothelium in Hypoplastic Left Heart Syndrome
Yu, Z.; Zhou, X.; Pastrana-Gomez, V.; Tian, L.; Nelson, T. J.; Snyder, M. P.; Wang, N.; Mital, S.; Chitayat, D.; Wu, J. C.; Rabinovitch, M.; Wu, S. M.; Miao, Y.; Gu, M.
10.1101/2021.08.30.457716 — developmental biology — Posted on 2021-09-09
2893 Widespread roles of Trypanosoma brucei ATR in nuclear genome function and transmission are linked to R-loops
Black, J. A.; Crouch, K.; Briggs, E. M.; Lemgruber, L.; Lapsley, C.; Tosi, L. R. O.; Mottram, J. C.; McCulloch, R.
10.1101/2021.09.09.459654 — cell biology — Posted on 2021-09-09
2895 Variant surface glycoprotein expression in human African trypanosomiasis patients
So, J.; Sudlow, S.; Sayeed, A.; Grudda, T.; Deborggraeve, S.; Ngoyi, D. M.; Desamber, D. K.; Wickstead, B.; Lejon, V.; Mugnier, M. R.
10.1101/2021.09.09.459620 — microbiology — Posted on 2021-09-09
2898 B cell-intrinsic requirement for WNK1 kinase in T cell-dependent antibody responses
Hayward, D.; Vanes, L.; Wissmann, S.; Sivapatham, S.; Hartweger, H.; Biggs O'May, J.; De Boer, L.; Mitter, R.; Kochl, R.; Stein, J. V.; Tybulewicz, V. L.
10.1101/2021.09.09.459588 — immunology — Posted on 2021-09-09
2899 Coupling between cerebrovascular oscillations and CSF flow fluctuation during wakefulness: An fMRI study
Yang, H.-C. S.; Inglis, B.; Talavage, T. M.; Vijayakrishnan Nair, V.; Yao, J. F.; Fitzgerald, B.; Schwichtenberg, A. J.; Tong, Y.
10.1101/2021.03.29.437406 — neuroscience — Posted on 2021-09-09
2901 Synaptomic analysis of dopaminergic inputs reveal hub synapses in the mouse striatum.
Paget-Blanc, V.; Pfeffer, M. E.; Pronot, M.; Lapios, P.; Angelo, M. F.; Walle, R.; Cordelieres, F. P.; Levet, F.; Claverol, S.; Lacomme, S.; Petrel, M.; Martin, C.; Pitard, V.; Desmedt-Peyrusse, V.; Biederer, T.; Perrais, D.; Trifilieff, P.; Herzog, E.
10.1101/2020.02.18.952978 — neuroscience — Posted on 2021-09-09
2905 A general theory for temperature-dependence in biology
Arroyo, J. I.; Diez, B.; Kempes, C. P.; West, G.; Marquet, P.
10.1101/2021.04.26.441387 — ecology — Posted on 2021-09-09
2907 An adjuvanted SARS-CoV-2 RBD nanoparticle elicits neutralizing antibodies and fully protective immunity in aged mice
Borriello, F.; Nanishi, E.; Seo, H.-S.; OMeara, T. R.; McGrath, M. E.; Saito, Y.; Haupt, R. E.; Chen, J.; Diray-Arce, J.; Song, K.; Xu, A. Z.; Caradonna, T. M.; Feldman, J.; Hauser, B. M.; Schmidt, A. G.; Baden, L. R.; Ernst, R. K.; Dillen, C.; Weston, S. M.; Johnson, R. M.; Hammond, H. L.; Yu, J.; Chang, A.; Hilgers, L.; Platenburg, P. P.; Dhe-Paganon, S.; Barouch, D. H.; Ozonoff, A.; Zanoni, I.; Frieman, M. B.; Dowling, D. J.; Levy, O.
10.1101/2021.09.09.459664 — immunology — Posted on 2021-09-09
2909 Remotely detected plant function in two midwestern prairie grassland experiments reveals belowground processes
Cavender-Bares, J.; Schweiger, A. K.; Gamon, J. A.; Gholizadeh, H.; Helzer, K.; Lapadat, C.; Madritch, M.; Townsend, P. A.; Wang, Z.; Hobbie, S. E.
10.1101/2021.09.08.459443 — ecology — Posted on 2021-09-09
2911 rbioacc: an R-package to analyse toxicokinetic data
Ratier, A.; Baudrot, V.; Kaag, M.; Siberchicot, A.; Lopes, C.; CHARLES, S.
10.1101/2021.09.08.459421 — ecology — Posted on 2021-09-09
2912 A virus-encoded microRNA contributes to evade innate immune response during SARS-CoV-2 infection
Singh, M.; Chazal, M.; Quarato, P.; Bourdon, L.; Malabat, C.; Vallet, T.; Vignuzzi, M.; van der Werf, S.; Behillil, S.; Donati, F.; Sauvonnet, N.; Nigro, G.; Bourgine, M.; Jouvenet, N.; Cecere, G.
10.1101/2021.09.09.459577 — molecular biology — Posted on 2021-09-09
2914 TAAC - TMS Adaptable Auditory Control: a universal tool to mask TMS click
Russo, S.; Sarasso, S.; Puglisi, G. E.; Dal Palu, D.; Pigorini, A.; Casarotto, S.; D'Ambrosio, S.; Astolfi, A.; Massimini, M.; Rosanova, M.; Fecchio, M.
10.1101/2021.09.08.459439 — neuroscience — Posted on 2021-09-09
2915 Specialization of the photoreceptor transcriptome by Srrm3-dependent microexons is required for outer segment maintenance and vision
Ciampi, L.; Mantica, F.; Lopez-Blanch, L.; Rodriguez-Marin, C.; Cianferoni, D.; Zang, J.; Permanyer, J.; Jimenez-Delgado, S.; Bonnal, S.; Miravet-Verde, S.; Ruprecht, V.; Neuhauss, S. C.; Banfi, S.; Carrella, S.; Serrano, L.; Head, S. A.; Irimia, M.
10.1101/2021.09.08.459463 — systems biology — Posted on 2021-09-09
2916 Radiotherapy induces specific miRNA expression profiles in glioblastoma exosomes
Boukredine, A.; Saada, S.; Durand, S.; Nivet, A.; Bessette, B.; Rehailia, A.; Clavere, P.; Jauberteau, M.-O.; Deluche, E.; Lalloue, F.
10.1101/2021.09.08.459416 — cancer biology — Posted on 2021-09-09
2917 Genome assembly and annotation of the tambaqui (Colossoma macropomum): an emblematic fish of the Amazon River basin
Hilsdorf, A. W. S.; Silva, M. U.; Coutinho, L. L.; Montenegro, H.; Almeida-Val, V. M. F.; Pinhal, D.
10.1101/2021.09.08.459456 — genomics — Posted on 2021-09-09
2918 Comprehensive analysis of DNA replication timing in genetic diseases and gene knockouts identifies MCM10 as a novel regulator of the replication program
Caballero, M.; Ge, T.; Rebelo, A. R.; Seo, S.; Kim, S.; Brooks, K.; Zuccaro, M. L.; Kanagaraj, R.; Vershkov, D.; Kim, D.; Smogorzewska, A.; Smolka, M. B.; Benvenisty, N.; West, S. C.; Egli, D. C.; Mace, E. M.; Koren, A.
10.1101/2021.09.08.459433 — genetics — Posted on 2021-09-09
2920 A Process-Based Model with Temperature, Water, and Lab-derived Data Improves Predictions of Daily Mosquito Density
Shutt, D. P.; Goodsman, D. W.; Hemez, Z. J. L.; Conrad, J. R.; Xu, C.; Osthus, D.; Russell, C.; Hyman, J. M.; Manore, C. A.
10.1101/2021.09.08.458905 — ecology — Posted on 2021-09-09
2921 Targeting Stem-loop 1 of the SARS-CoV-2 5'UTR to suppress viral translation and Nsp1 evasion
Vora, S. M.; Fontana, P.; Leger, V.; Zhang, Y.; Fu, T.-M.; Lieberman, J.; Gehrke, L.; Shi, M.; Wang, L.; Wu, H.
10.1101/2021.09.09.459641 — molecular biology — Posted on 2021-09-09
2922 The gut microbial signature of gestational diabetes mellitus and the association with diet intervention
Wu, N.; Zhou, J.; Mo, H.; Mu, Q.; Su, H.; Li, M.; Yu, Y.; Liu, A.; Zhang, Q.; Xu, J.; Yu, W.-D.; Liu, P.; Liu, G.
10.1101/2021.09.07.459364 — microbiology — Posted on 2021-09-09
2923 Functional characterization of the biogenic amine transporter system on human macrophages
Mackie, P. M.; Gopinath, A.; Montas, D. M.; Nielsen, A.; Nolan, R.; Runner, K.; Matt, S.; McNamee, J.; Ricklan, J.; Adachi, K.; Doty, A.; Ramirez-Zamora, A.; Yan, L.; Gaskill, P. J.; Streit, W. J.; Okun, M. S.; Khoshbouei, H.
10.1101/2021.09.08.459459 — neuroscience — Posted on 2021-09-09
2925 (Un)common space in infant neuroimaging studies: a systematic review of infant templates
Dufford, A. J.; Hahn, C. A.; Peterson, H.; Gini, S.; Mehta, S.; Alfano, A.; Scheinost, D.
10.1101/2021.09.08.459462 — neuroscience — Posted on 2021-09-09
2926 Feasibility of Administering Human Pancreatic Cancer Chemotherapy in Spontaneous Pancreatic Cancer Mouse Model
Delahoussaye, A. M.; Jaoude, J. A.; Fujimoto, T. N.; Molkentine, J.; Garcia, C. J. G.; Gay, J. P.; Feng, N.; Marszalek, J.; Taniguchi, C. M.
10.1101/2021.09.08.459476 — cancer biology — Posted on 2021-09-09
2929 SARS-CoV-2 triggers DNA damage response in Vero E6 cells
Victor, J.; Deutsch, J.; Whitaker, A.; Lamkin, E. N.; March, A.; Zhou, P.; Botten, J. W.; Chatterjee, N.
10.1101/2021.09.08.459535 — cancer biology — Posted on 2021-09-09
2930 Heat efficiently inactivates coronaviruses inside vehicles
Karthigeyan, K. P.; Flanigan, C.; Machado, D. J.; Kiziltas, A. A.; Janies, D. A.; Chen, J.; Cooke, D.; Lee, M. V.; Saif, L. J.; Henegar, S.; Jahnes, J.; Mielewski, D. F.; Kwiek, J. J.
10.1101/2021.09.08.459486 — microbiology — Posted on 2021-09-09
2931 A thermostable oral SARS-CoV-2 vaccine induces mucosal and protective immunity
Bellier, B.; Saura, A.; Lujan, L.; Molina, C.; Lujan, H. D.; Klatzmann, D.
10.1101/2021.09.09.459634 — immunology — Posted on 2021-09-09
2932 Digital Spatial Profiling of Collapsing Glomerulopathy
Smith, K. D.; Henriksen, K.; Nicosia, R. F.; Alpers, C. E.; Akilesh, S.
10.1101/2021.09.08.459502 — pathology — Posted on 2021-09-09
2935 SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning
Gamart, J.; Barozzi, I.; Laurent, F.; Reinhardt, R.; Ramos Martins, L.; Oberholzer, T.; Visel, A.; Zeller, R.; Zuniga, A.
10.1101/2021.09.08.459466 — developmental biology — Posted on 2021-09-09
2942 Angiotensin-converting enzyme governs endogenous opioid signaling and synaptic plasticity in nucleus accumbens
Trieu, B. H.; Remmers, B. C.; Toddes, C.; Brandner, D. D.; Xie, W.; More, S.; Rothwell, P. E.
10.1101/2021.09.08.459469 — neuroscience — Posted on 2021-09-09
2944 A thermodynamic model for interpreting tryptophan excitation-energy-dependent fluorescence spectra provides insight into protein conformational sampling and stability
Kwok, A.; Camacho, I.; Winter, S.; Knight, M.; Meade, R.; van der Kamp, M.; Turner, A.; O'Hara, J.; Mason, J.; Jones, A. R.; Arcus, V.; Pudney, C. R.
10.1101/2021.09.09.459605 — biophysics — Posted on 2021-09-09
2946 Effects of age and surface instability on the control of the center of mass
van den Bogaart, M.; Bruijn, S. M.; Spildooren, J.; van Dieën, J. H.; Meyns, P.
10.1101/2021.09.08.459390 — bioengineering — Posted on 2021-09-09
2948 Mechanism of a COVID-19 nanoparticle vaccine candidate that elicits a broadly neutralizing antibody response to SARS-CoV-2 variants
Zhang, Y.-N.; Paynter, J.; Sou, C.; Fourfouris, T.; Wang, Y.; Abraham, C.; Ngo, T.; Zhang, Y.; He, L.; Zhu, J.
10.1101/2021.03.26.437274 — immunology — Posted on 2021-09-09
2949 Circulating multimeric immune complexes drive immunopathology in COVID-19
Ankerhold, J.; Giese, S.; Kolb, P.; Maul-Pavicic, A.; Voll, R. E.; Goeppert, N.; Ciminski, K.; Kreutz, C.; Lother, A.; Salzer, U.; Bildl, W.; Welsink, T.; Morgenthaler, N.; Busse Grawitz, A.; Huzly, D.; Schwemmle, M.; Hengel, H.; Falcone, V.
10.1101/2021.06.25.449893 — immunology — Posted on 2021-09-09
2950 LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants
Westendorf, K.; Zentelis, S.; Foster, D.; Vaillancourt, P.; Wiggin, M.; Lovett, E.; van der Lee, R.; Hendle, J.; Pustilnik, A.; Sauder, J. M.; Kraft, L.; Hwang, Y.; Siegel, R. W.; Chen, J.; Heinz, B. A.; Higgs, R. E.; Kalleward, N.; Jepson, K.; Goya, R.; Smith, M. A.; Collins, D. W.; Pellacani, D.; Xiang, P.; de Puyraimond, V.; Ricicova, M.; Devorkin, L.; Pritchard, C.; O'Neill, A.; Dalal, K.; Panwar, P.; Dhupar, H.; Garces, F. A.; Cohen, C.; Dye, J.; Huie, K. E.; Badger, C. V.; Kobasa, D.; Audet, J.; Freitas, J. J.; Hassanali, S.; Hughes, I.; Munoz, L.; Palma, H. C.; Ramamurthy, B.; Cross, R.
10.1101/2021.04.30.442182 — immunology — Posted on 2021-09-09
2953 ShareLoc - an open platform for sharing localization microscopy data
Bai, J.; Ouyang, W.; Singh, M. K.; Leterrier, C.; Barthelemy, P.; Barnett, S. F. H.; Klein, T.; Sauer, M.; Kanchanawong, P.; Bourg, N.; Cohen, M. M.; Lelandais, B.; Zimmer, C.
10.1101/2021.09.08.459385 — bioinformatics — Posted on 2021-09-09
2954 Effects of age and surface instability on the control of the center of mass
van den Bogaart, M.; Bruijn, S. M.; Spildooren, J.; van Dieën, J. H.; Meyns, P.
10.1101/2021.09.08.459390 — bioengineering — Posted on 2021-09-09
2955 Effects of age and surface instability on the control of the center of mass
van den Bogaart, M.; Bruijn, S. M.; Spildooren, J.; van Dieën, J. H.; Meyns, P.
10.1101/2021.09.08.459390 — bioengineering — Posted on 2021-09-09
2956 Effects of age and surface instability on the control of the center of mass
van den Bogaart, M.; Bruijn, S. M.; Spildooren, J.; van Dieën, J. H.; Meyns, P.
10.1101/2021.09.08.459390 — bioengineering — Posted on 2021-09-09
2957 Effects of age and surface instability on the control of the center of mass
van den Bogaart, M.; Bruijn, S. M.; Spildooren, J.; van Dieën, J. H.; Meyns, P.
10.1101/2021.09.08.459390 — bioengineering — Posted on 2021-09-09
2958 The X-linked splicing regulator MBNL3 has been co-opted to restrict placental growth in eutherians
Spruce, T.; Plass, M.; Gohr, A.; Ray, D.; Martinez de Lagran, M.; Rot, G.; Novoa, A.; Burguera, D.; Permanyer, J.; Miret, M.; Zheng, H.; Swanson, M.; Morris, Q.; Mallo, M.; Dierssen, M.; Hughes, T. R.; Pernaute, B.; Irimia, M.
10.1101/2021.09.08.459166 — evolutionary biology — Posted on 2021-09-09
2960 Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-2
Hatton, C. F.; Botting, R. A.; Duenas, M. E.; Haq, I. J.; Verdon, B.; Thompson, B. J.; Stremenova Spegarova, J.; Gothe, F.; Stephenson, E. A.; Gardner, A. I.; Murphy, S.; Scott, J.; Garnett, J. P.; Carrie, S.; Powell, J.; Khan, A. C. M.; Huang, L.; Hussain, R.; Coxhead, J.; Davey, T.; Simpson, J.; Haniffa, M.; Hambleton, S.; Brodlie, M.; Ward, C.; Trost, M.; Reynolds, G.; Duncan, C. J. A.
10.1101/2021.02.17.431591 — immunology — Posted on 2021-09-09
2961 The ChAdOx1 vectored vaccine, AZD2816, induces strong immunogenicity against SARS-CoV-2 Beta (B.1.351) and other variants of concern in preclinical studies.
Spencer, A. J.; Morris, S.; Ulaszewska, M.; Powers, C.; Kaliath, R.; Bissett, C. D.; Truby, A.; Thakur, N.; Newman, J.; Allen, E. R.; Rudiansyah, I.; Lui, C.; Dejnirattisai, W.; Mongkolsapaya, J.; Davies, H.; Donnellan, F. R.; Pulido, D.; Peacock, T. P.; Barclay, W. S.; Bright, H.; Ren, K.; Screaton, G.; McTammy, P.; Bailey, D.; Gilbert, S. C.; Lambe, T.
10.1101/2021.06.08.447308 — immunology — Posted on 2021-09-09
2962 Flexible Path Planning through Vicarious Trial and Error
Krichmar, J. L.; Ketz, N. A.; Pilly, P. K.; Soltoggio, A.
10.1101/2021.09.08.459317 — neuroscience — Posted on 2021-09-09
2964 Structural origins of Escherichia coli RNA polymerase open promoter complex stability
Saecker, R. M.; Chen, J.; Chiu, C. E.; Malone, B.; Sortiris, J.; Ebrahim, M.; Yen, L. Y.; Eng, E. T.; Darst, S. A.
10.1101/2021.09.08.459427 — biophysics — Posted on 2021-09-09
2965 Combined free energy calculation and machine learning methods for understanding ligand unbinding kinetics
Badaoui, M.; Buigues, P. J.; Berta, D.; Mandana, G. M.; Gu, H.; Dickson, C. J.; Hornak, V.; Kato, M.; Molteni, C.; Parsons, S. D.; Rosta, E.
10.1101/2021.09.08.459492 — biophysics — Posted on 2021-09-09
2966 MOLECULAR VIDEOGAMING: SUPER-RESOLVED TRAJECTORY-BASED NANOCLUSTERING ANALYSIS USING SPATIO-TEMPORAL INDEXING
Wallis, T. P.; Jiang, A.; Hou, H.; Gormal, R. S.; Durisic, N.; Balistreri, G.; Joensuu, M.; Meunier, F. A.
10.1101/2021.09.08.459552 — biophysics — Posted on 2021-09-09
2967 CardIAP: Calcium images analyzer web application
Velez Rueda, A. J.; Garcia Smith, A.; Gonano, L. A.; Fornasari, S.; Parisi, G.; Sommese, L. M.
10.1101/2021.09.08.452919 — bioinformatics — Posted on 2021-09-09
2977 Identification of a stress-sensitive anorexigenic neurocircuit from medial prefrontal cortex to lateral hypothalamus in humans and mice
Clarke, R. E.; Voigt, K.; Stark, R.; Bharania, U.; Dempsey, H.; Reichenbach, A.; Lockie, S.; Mequinion, M.; Reed, F.; Rawlinson, S.; Nunez-Iglesias, J.; Foldi, C. J.; Verdejo-Garcia, A.; Kravitz, L.; Andrews, Z. B.
10.1101/2021.09.07.459350 — neuroscience — Posted on 2021-09-09
2984 Neural pathways linking hypoxia with pectoral fin movements in Danio rerio
Rosales, K.; Yeh, C. M.; How, J. J.; Villa-Real, R.; DePasquale, E.; Groisman, A.; Chalasani, S. H.
10.1101/655084 — neuroscience — Posted on 2021-09-09
2985 Intestine-to-neuronal signaling alters risk-taking behaviors in food-deprived Caenorhabditis elegans
Matty, M. A.; Lau, H. E.; Singh, A.; Haley, J. A.; Chakraborty, A.; Kono, K.; Reddy, K. C.; Hansen, M.; Chalasani, S.
10.1101/156109 — neuroscience — Posted on 2021-09-09
2988 Population genomics of Bacillus anthracis from an anthrax hyperendemic area reveals transmission processes across spatial scales and unexpected within-host diversity
Forde, T. L.; Dennis, T. P. W.; Aminu, O. R.; Harvey, W. T.; Hassim, A.; Kiwelu, I.; Medvecky, M.; Mshanga, D.; van Heerden, H.; Vogel, A.; Zadoks, R. N.; Mmbaga, B. T.; Lembo, T.; Biek, R.
10.1101/2021.09.07.459365 — genomics — Posted on 2021-09-09
2989 Modelling the spatiotemporal spread of beneficial alleles using ancient genomes
Muktupavela, R. A.; Petr, M.; Segurel, L.; Korneliussen, T. S.; Novembre, J.; Racimo, F.
10.1101/2021.07.21.453231 — evolutionary biology — Posted on 2021-09-09
2990 Riparian forest restoration as sources of biodiversity and ecosystem functions in anthropogenic landscapes
Antonini, Y.; Beirao, M. V.; Costa, F. V.; Azevedo, C. S.; Wojakowski, M.; Kozovits, A.; Pires, M. R. S.; Sousa, H. C.; Messias, M. C. T. B.; Fujaco, M. A. G.; Leite, M. G. P.; Martins, J. P. V.; Monteiro, G. F.; Dirzo, R.
10.1101/2021.09.08.459375 — ecology — Posted on 2021-09-09
2992 Genome-wide transcriptional profiling uncovers a similar oligodendrocyte-related transcriptional response to acute and chronic alcohol drinking in the amygdala
Narendra, S.; Klengel, C.; Hamzeh, B.; Patel, D.; Otten, J.; Lardenoije, R.; Newman, E. L.; Miczek, K. A.; Klengel, T.; Ressler, K. J.; Suh, J.
10.1101/2021.09.07.459347 — neuroscience — Posted on 2021-09-09
2994 CaPTure: Calcium Peak Toolbox for analysis of in vitro calcium imaging data
Tippani, M.; Pattie, E. A.; Davis, B. A.; Nguyen, C. V.; Wang, Y.; Sripathy, S. R.; Maher, B. J.; Martinowich, K.; Jaffe, A. E.; Page, S. C.
10.1101/2021.09.08.458611 — neuroscience — Posted on 2021-09-09
2995 Beyond traditional visual sleep scoring: massive feature extraction and unsupervised clustering of sleep time series
Decat, N.; Walter, J.; Koh, Z. H.; Sribanditmongkol, P.; Fulcher, B. D.; Windt, J. M.; Andrillon, T.; Tsuchiya, N.
10.1101/2021.09.08.458981 — neuroscience — Posted on 2021-09-09
2996 Concurrent Multimodal Data Acquisition During Brain Scanning is within Reach
Sola Molina, R. M.; Lamp, G.; Hugrass, L. E.; Beaton, R.; De Man, M.; Wise, L.; Crewther, D. P.; Goodale, M.; Crewther, S. G.
10.1101/2021.09.07.459353 — neuroscience — Posted on 2021-09-09
2998 Simultaneous Cardiac and Neurological Monitoring to Assess Chemical Exposures and Drug Toxicity in Xenopus Laevis
Xia, X.; Zhang, J.; Vishwanath, M.; Sarafan, S.; Torres, R. S. T.; Le, T.; Lau, M. P. H.; Nguyen, A. H.; Cao, H.
10.1101/2021.09.07.459337 — physiology — Posted on 2021-09-09
3000 Interpretable deep learning for chromatin-informed inference of transcriptional programs driven by somatic alterations across cancers
Tao, Y.; Ma, X.; Laliotis, G. I.; Zuniga, A. G.; Palmer, D.; Toska, E.; Schwartz, R.; Lu, X.; Osmanbeyoglu, H. U.
10.1101/2021.09.07.459263 — bioinformatics — Posted on 2021-09-09
3003 Population structure and environmental niches of Rimicaris shrimps from the Mid Atlantic Ridge
Methou, P.; Hernandez-Avila, I.; Cathalot, C.; Bonavita, M.-A. C.; Pradillon, F.
10.1101/2021.06.27.450074 — ecology — Posted on 2021-09-09
3006 Advancing motion denoising of multiband resting state functional connectivity fMRI data
Williams, J. C.; Tubiolo, P. N.; Luceno, J. R.; Van Snellenberg, J. X.
10.1101/860635 — neuroscience — Posted on 2021-09-09
3008 Targeted rescue of synaptic plasticity improves cognitive decline in sepsis-associated encephalopathy
Grünewald, B.; Wickel, J.; Hahn, N.; Hörhold, F.; Rupp, H.; Chung, H.-Y.; Haselmann, H.; Strauss, A. S.; Schmidl, L.; Hempel, N.; Grünewald, L.; Urbach, A.; Bauer, M.; Toyka, K. V.; Blaess, M.; Claus, R. A.; König, R.; Geis, C.
10.1101/2021.03.04.433352 — neuroscience — Posted on 2021-09-09
3009 Clipper: p-value-free FDR control on high-throughput data from two conditions
Ge, X.; Chen, Y. E.; Song, D.; McDermott, M.; Woyshner, K.; Manousopoulou, A.; Wang, N.; Li, W.; Wang, L. D.; Li, J. J.
10.1101/2020.11.19.390773 — bioinformatics — Posted on 2021-09-09
3013 Spinal reconsolidation engages non-ionotropic NMDA receptor signaling to reverse pain hypersensitivity
D'Souza, A. J.; Rodriguez-Hernandez, D.; Zhang, H.; He, D.; Zain, M.; Fung, S.; Bennett, L. A.; Bonin, R. P.
10.1101/2021.09.08.458120 — neuroscience — Posted on 2021-09-09
3015 Whole-genome sequence analysis unveils different origins of European and Asiatic mouflon and domestication-related genes in sheep
Chen, Z.; Xu, Y.-X.; Xie, X.-L.; Wang, D.-F.; Aguilar-Gomez, D.; Liu, G.-J.; Li, X.; Esmailizadeh, A.; Rezaei, V.; Kantanen, J.; Ammosov, I.; Nosrati, M.; Periasamy, K.; Coltman, D. W.; Lenstra, J. A.; Nielsen, R. A.; Li, M.-h.
10.1101/2021.09.07.458675 — evolutionary biology — Posted on 2021-09-09
3016 GENE DUPLICATION TO THE Y CHROMOSOME IN TRINIDADIAN GUPPIES
Lin, Y.; Darolti, I.; Furman, B. L. S.; Almeida, P.; Sandkam, B. A.; Breden, F.; Wright, A. E.; Mank, J. E.
10.1101/2021.02.16.431319 — evolutionary biology — Posted on 2021-09-09
3017 Maternal SMCHD1 regulates Hox gene expression andpatterning in the mouse embryo
Benetti, N.; Gouil, Q.; Tapia del Fierro, A.; Beck, T.; Breslin, K.; Keniry, A.; McGlinn, E.; Blewitt, M. E.
10.1101/2021.09.08.459528 — developmental biology — Posted on 2021-09-08
3019 Land Use Cover changes in the western escarpment of Rift Valley in the Gamo Zone, Southern Ethiopia
Dingamo, T. D.; Takele, S.; Demissew, S.; Woldu, Z.; Temesgen Dingamo1, Sebsebe Demissew3, Zerihun Woldu3 and Serekebirhan Takele2,
10.1101/2021.09.08.459379 — ecology — Posted on 2021-09-08
3020 Off-target expression of Cre-dependent adeno-associated viruses in wild type C57BL/6J mice
Botterill, J. J.; Khlaifia, A.; Walters, B. J.; Brimble, M. A.; Scharfman, H. E.; Arruda-Carvalho, M.
10.1101/2021.09.08.459310 — neuroscience — Posted on 2021-09-08
3022 Polycomb group protein CBX7 represses cardiomyocyte proliferation via modulation of the TARDBP/Rbm38 axis
Cho, K.; Mark, A.; Bae, S.; Kim, S.; Kim, J. E.; Jang, E. Y.; Husain, A.; Sutliff, R. L.; Calvert, J. W.; Park, C.; Yoon, Y.-s.
10.1101/2021.09.08.459291 — developmental biology — Posted on 2021-09-08
3026 SARS-CoV-2 expresses a microRNA-like small RNA able to selectively repress host genes
Pawlica, P.; Yario, T.; White, S.; Wang, J.; Moss, W.; Hui, P.; Vinetz, J. M.; Steitz, J. A.
10.1101/2021.09.08.459464 — microbiology — Posted on 2021-09-08
3030 Interleukin-6 Signaling Mediates Cartilage Degradation and Pain in Post-Traumatic Osteoarthritis
Liao, Y.; Ren, Y.; Luo, X.; Long, J. T.; Mirando, A. J.; Leinroth, A.; Ji, R. R.; Hilton, M. J.
10.1101/2021.09.08.459303 — pathology — Posted on 2021-09-08
3031 A systematic analysis of diet-induced nephroprotection reveals overlapping and conserved changes in cysteine catabolism
Koehler, F. C.; Fu, C.-Y.; Spaeth, M. R.; Hoyer-Allo, K. J. R.; Bohl, K.; Goebel, H.; Lackmann, J.-W.; Grundmann, F.; Osterholt, T.; Gloistein, C.; Steiner, J. D.; Antebi, A.; Benzing, T.; Schermer, B.; Schwarz, G.; Burst, V.; Mueller, R.-U.
10.1101/2021.09.08.459468 — biochemistry — Posted on 2021-09-08
3032 Semisynthesis of functional transmembrane proteins in GUVs
Podolsky, K. A.; Masubuchi, T.; Debelouchina, G. T.; Hui, E.; Devaraj, N. K.
10.1101/2021.09.08.459519 — biochemistry — Posted on 2021-09-08
3033 Deep sampling of ancestral genetic diversity reveals Saccharomyces cerevisiae pre-domestication life histories
Lee, T. J.; Liu, Y.-C.; Liu, W.-A.; Lin, Y.-F.; Lee, H.-H.; Ke, H.-M.; Huang, J.-P.; Lu, M.-Y. J.; Hsieh, C.-L.; Chung, K.-F.; Liti, G.; Tsai, I. J.
10.1101/2021.09.07.459046 — genomics — Posted on 2021-09-08
3034 A CRISPR-Cas assisted shotgun mutagenesis method for evolutionary genome engineering
Zhao, M.; Gao, M.; Xiong, L.; Liu, Y.; Tao, X.; Gao, B.; Liu, M.; Wang, F.-Q.; Wei, D.-Z.
10.1101/2021.09.08.459399 — evolutionary biology — Posted on 2021-09-08
3035 Intercellular crosstalk regulating ARRB2/RARRES1 is involved in transition from fibrosis to cancer
Schierwagen, R.; Dietrich, P.; Heinzen, J.; Klein, S.; Uschner, F. E.; Ortiz, C.; Tyc, O.; Torres, S.; Hieber, C.; Kraus, N.; Premont, R. T.; Gruenewald, L. D.; Poisson, J.; Ratou, P.-E.; Kristiansen, G.; Gracia-Sancho, J.; Poglitsch, M.; Ludwig-Portugall, I.; Walther, T.; Trautwein, C.; Abdullah, Z.; Muench, C.; Welsch, C.; Fernandez, M.; Zeuzem, S.; Moreau, R.; Helllerbrand, C.; Rombouts, K.; Kastenmueller, W.; Diehl, A. M.; Trebicka, J.
10.1101/2021.09.08.458161 — molecular biology — Posted on 2021-09-08
3036 Host- and age-dependent transcriptional changes in Mycobacterium tuberculosis cell envelope biosynthesis genes after exposure to human alveolar lining fluid
Allue-Guardia, A.; Garcia-Vilanova, A.; Olmo-Fontanez, A. M.; Peters, J.; Maselli, D. J.; Turner, J.; Schlesinger, L. S.; Torrelles, J. B.
10.1101/2021.09.08.459334 — molecular biology — Posted on 2021-09-08
3038 Dysfunction of novel energy sensor NFE2L1 leads to uncontrollable AMPK signal and glucose metabolism reprogramming
Yang, Q.; Zhao, W.; Li, P.; Zhou, X.; Ning, H.; Shi, R.; Gou, S.; Chen, Y.; Zhai, W.; Wu, Y.; Li, G.; Chen, Z.; Ren, Y.; Xing, Y.; Gao, Y.; Zhang, Y.; Qi, Y.; Qiu, L.
10.1101/2021.09.07.459348 — molecular biology — Posted on 2021-09-08
3044 Circadian patterns of energy metabolism are only partially reconstituted in gnotobiotic mice
Hoces, D.; Lan, J.; Sun, W.; Geiser, T.; Arnoldini, M.; Nowok, S.; Macpherson, A. J.; Stecher, B.; Zenobi, R.; Hardt, W.-D.; Wolfrum, C.; Slack, E.
10.1101/2021.09.08.456534 — microbiology — Posted on 2021-09-08
3046 Targeted isolation of panels of diverse human broadly neutralizing antibodies against SARS-like viruses
He, W.-t.; Musharrafieh, R.; Song, G.; Dueker, K.; Callaghan, S.; Yong, P.; Beutler, N.; Torres, J. L.; Volk, R. M.; Zhou, P.; Yuan, M.; Liu, H.; Anzanello, F.; Parren, M.; Garcia, E.; Rawlings, S. A.; Smith, D. M.; Wilson, I. A.; Ward, A. B.; Rogers, T.; Burton, D. R.; Andrabi, R.
10.1101/2021.09.08.459480 — immunology — Posted on 2021-09-08
3048 Prospective cohort study reveals unexpected aetiologies of livestock abortion in northern Tanzania
Thomas, K. M.; Kibona, T.; Claxton, J. R.; de Glanville, W. A.; Lankester, F.; Amani, N.; Buza, J.; Carter, R. W.; Chapman, G. E.; Crump, J. A.; Dagleish, M.; Halliday, J. E. B.; Hamilton, C. M.; Innes, E. A.; Katzer, F.; Livingstone, M.; Longbottom, D.; Millins, C.; Mmbaga, B. T.; Mosha, V.; Nyarobi, J.; Nyasebwa, O.; Russell, G. C.; Sanka, P. N.; Semango, G.; Wheelhouse, N.; Willett, B. J.; Cleaveland, S.; Allan, K. J.
10.1101/2021.08.23.457407 — systems biology — Posted on 2021-09-08
3050 Characterization of the Endogenous DAF-12 Ligand and Its Use as an Anthelmintic Agent in Strongyloides stercoralis
Wang, Z.; Cheong, M. C.; Tsien, J.; Deng, H.; Qin, T.; Stoltzfus, J. D. C.; Jaleta, T. G.; Li, X.; Lok, J. B.; Kliewer, S. A.; Mangelsdorf, D. J.
10.1101/2021.09.07.459359 — pharmacology and toxicology — Posted on 2021-09-08
3051 Interplay between mitochondria and reactive oxygen and nitrogen species in metabolic adaptation to hypoxia in facioscapulohumeral muscular dystrophy: potential therapeutic targets.
Heher, P.; Ganassi, M.; Weidinger, A.; Engquist, E. N.; Pruller, J.; Nguyen, T. H.; Tassin, A.; Decleves, A. E.; Mamchaoui, K.; Grillari, J.; Kozlov, A.; Zammit, P. S.
10.1101/2021.09.08.459509 — pathology — Posted on 2021-09-08
3052 A redox cycle with complex II promotes sulfide quinone oxidoreductase dependent H2S oxidation
Kumar, R.; Landry, A. P.; Guha, A.; Vitvitsky, V.; Lee, H.-J.; Seike, K.; Reddy, P.; Lyssiotis, C. A.; Banerjee, R.
10.1101/2021.09.08.459449 — biochemistry — Posted on 2021-09-08
3053 Haplotype-aware inference of human chromosome abnormalities
Ariad, D.; Yan, S. M.; Victor, A. R.; Barnes, F. L.; Zouves, C. G.; Viotti, M.; McCoy, R. C.
10.1101/2021.05.18.444721 — genomics — Posted on 2021-09-08
3054 Mct11 deficiency alters hepatic glucose metabolism and energy homeostasis
Ainbinder, A.; Zhao, L.; Glover, P.; Gelinas-Roa, K.; Rusu, V.; Harney, A.; Hoch, E.; Deik, A. A.; Pierce, K. A.; Bullock, K.; Dennis, C.; Jeanfavre, S.; Krejci, J.; Choi, J.; Hollenberg, A. N.; Centeno-Cruz, F.; Barajas-Olmos, F.; Zerrweck, C.; Orozco, L.; Clish, C. B.; Lander, E. S.; Florez, J. C.; Jacobs, S. B. R.
10.1101/2021.09.08.459307 — genetics — Posted on 2021-09-08
3057 HP1γ sets the biological age of the intestinal epithelium
Mata -Garrido, J.; Chang, Y.; Chang-Marchand, Y.; Cherbuy, C.; Batsche, E.; Revechon, G.; Eriksson, M.; Muchardt, C.; Arbibe, L.
10.1101/2020.12.30.424798 — cell biology — Posted on 2021-09-08
3059 CsrA-controlled proteins reveal new dimensions of Acinetobacter baumannii desiccation tolerance
Oda, Y.; Shapiro, M. M.; Lewis, N. M.; Zhong, X.; Huse, H. K.; Zhong, W.; Bruce, J. E.; Manoil, C.; Harwood, C. S.
10.1101/2021.08.11.455981 — microbiology — Posted on 2021-09-08
3060 Cigarette smoke preferentially induces full length ACE2 exposure in primary human airway cells but does not alter susceptibility to SARS-CoV-2 infection
Guo, W.; Ortmann, B.; Crozier, T.; Greenwood, E. J.; Kottmann, D.; Mahadeva, R.; Nathan, J. A.; Lehner, P. J.; McCaughan, F.; Porter, L.
10.1101/2021.09.08.459428 — microbiology — Posted on 2021-09-08
3062 In vitro Functional Analysis of pgRNA Sites Regulating Assembly of Hepatitis B Virus.
Patel, N.; Clark, S.; Weiss, E. U.; Mata, C. P.; Bohon, J.; Farquhar, E.; Maskell, D. P.; Ranson, N. A.; Twarock, R.; Stockley, P. G.
10.1101/2021.09.08.459240 — microbiology — Posted on 2021-09-08
3063 Angicin, a novel bacteriocin of Streptococcus anginosus
Vogel, V.; Bauer, R.; Mauerer, S.; Schiffelholz, N.; Haupt, C.; Seibold, G. M.; Faendrich, M.; Walther, P.; Spellerberg, B.
10.1101/2021.09.08.459082 — microbiology — Posted on 2021-09-08
3064 Gut microbiota and age shape susceptibility to clostridial enteritis in lorikeets under human care
Minich, D.; Madden, C.; Navarro, M.; Glowacki, L.; French-Kim, K.; Chan, W.; Evans, M. V.; Soares, K. O.; Mrofchak, R.; Madan, R.; Ballash, G. A.; LaPerle, K.; Paul, S.; Vodovotz, Y.; Uzal, F. A.; Martinez, M.; Hausmann, J.; Junge, R. E.; Hale, V. L.
10.1101/2021.09.08.459483 — microbiology — Posted on 2021-09-08
3065 TET1 controls Cxcl1 induction by DNA demethylation and promotes neutrophil recruitment during acute lung injury
Yee, K. M.; Shuai, R. W.; Liu, B.; Huynh, C. A.; Niu, C.; Lee, H. R.; Lee, M. S.; Wen, J.; Zou, J.; Wu, J.; Shuai, K.
10.1101/2021.09.07.459280 — immunology — Posted on 2021-09-08
3066 SARS-CoV-2 mRNA vaccination elicits robust and persistent T follicular helper cell response in humans
Mudd, P. A.; Minervina, A. A.; Pogorelyy, M. V.; Turner, J. S.; Kim, W.; Kalaidina, E.; Petersen, J.; Schmitz, A. J.; Lei, T.; Haile, A.; Kirk, A. M.; Mettelman, R. C.; Crawford, J. C.; Nguyen, T. H. O.; Rowntree, L. C.; Rosati, E.; Klebert, M. K.; Suessen, T.; Middleton, W. D.; the SJTRC Study Team, ; Wolf, J.; Teefey, S. A.; O'Halloran, J.; Presti, R. M.; Kedzierska, K.; Rossjohn, J.; Thomas, P.; Ellebedy, A.
10.1101/2021.09.08.459485 — immunology — Posted on 2021-09-08
3067 Predicting perturbation effects from resting state activity using functional causal flow
Nejatbakhsh, A.; Fumarola, F.; Esteki, S.; Toyoizumi, T.; Kiani, R.; Mazzucato, L.
10.1101/2020.11.23.394916 — neuroscience — Posted on 2021-09-08
3069 Design principles of collateral sensitivity-based dosing strategies
Aulin, L. B. S.; Liakopoulos, A.; van der Graaf, P. H.; Rozen, D. E.; van Hasselt, J. G. C.
10.1101/2021.03.31.437927 — pharmacology and toxicology — Posted on 2021-09-08
3071 Modeling miRNA-driven post-transcriptional regulation by using exon-intron split analysis (EISA) in pigs
Marmol-Sanchez, E.; Cirera, S.; Zingaretti, L.; Jacobsen, M. J.; Ramayo-Caldas, Y.; Jorgensen, C. B.; Fredholm, M.; Cardoso, T. F.; Quintanilla, R.; Amills, M.
10.1101/2021.07.14.452370 — genomics — Posted on 2021-09-08
3077 Comparative Analysis of T Cell Spatial Proteomics and the Influence of HIV Expression
Oom, A. L.; Stoneham, C. A.; Lewinski, M. K.; Richards, A.; Wozniak, J.; Shams-Ud-Doha, K.; Gonzalez, D.; Krogan, N. J.; Guatelli, J.
10.1101/2021.03.17.435902 — cell biology — Posted on 2021-09-08
3079 A new type of mouse gaze shift is led by directed saccades
Zahler, S. H.; Taylor, D. E.; Wong, J. Y.; Adams, J. M.; Feinberg, E. H.
10.1101/2021.02.10.430669 — neuroscience — Posted on 2021-09-08
3080 GPCR-G protein selectivity - a unified meta-analysis
Hauser, A. S.; Avet, C.; Normand, C.; Manchini, A.; Inoue, A.; Bouvier, M.; Gloriam, D.
10.1101/2021.09.07.459250 — pharmacology and toxicology — Posted on 2021-09-08
3083 Age-related differences in immune dynamics during SARS-CoV-2 infection in rhesus macaques
Speranza, E.; Purushotham, J. N.; Port, J. R.; Schwarz, B.; Flagg, M.; Williamson, B. N.; Feldmann, F.; Singh, M.; Perez-Perez, L.; Sturdevant, G. L.; Roberts, L. M.; Carmody, A.; Schulz, J. E.; van Doremalen, N.; Okumura, A.; Lovaglio, J.; Hanley, P.; Shaia, C.; Germain, R.; Best, S.; Munster, V.; Bosio, C.; de Wit, E.
10.1101/2021.09.08.459430 — immunology — Posted on 2021-09-08
3086 Inhibitory Acetylation of Pyruvate Dehydrogenase Promotes Diastolic Dysfunction in Mice
Thapa, D.; Bugga, P.; Mushala, B. A. S.; Manning, J. R.; Stoner, M. W.; McMahon, B.; Xie, B.; Edmunds, L. R.; Jurczak, M. J.; Scott, I.
10.1101/2021.09.07.459319 — physiology — Posted on 2021-09-08
3087 Evidence for a selective link between cooperation and individual recognition
Tumulty, J. P.; Miller, S. E.; Van Belleghem, S. M.; Weller, H. I.; Jernigan, C. M.; Vincent, S.; Staudenraus, R. J.; Legan, A. W.; Polnaszek, T. J.; Uy, F. M. K.; Walton, A.; Sheehan, M. J.
10.1101/2021.09.07.459327 — animal behavior and cognition — Posted on 2021-09-08
3090 An anti-SARS-CoV-2 non-neutralizing antibody with Fc-effector function defines a new NTD epitope and delays neuroinvasion and death in K18-hACE2 mice
Beaudoin-Bussieres, G.; Chen, Y.; Ullah, I.; Prevost, J.; Tolbert, W. D.; Symmes, K.; Ding, S.; Benlarbi, M.; Gong, S. Y.; Tauzin, A.; Gasser, R.; Chatterjee, D.; Vezina, D.; Goyette, G.; Richard, J.; Zhou, F.; Stamatatos, L.; McGuire, A. T.; Charest, H.; Roger, M.; Pozharski, E.; Kumar, P.; Mothes, W.; Uchil, P. D.; Pazgier, M.; Finzi, A.
10.1101/2021.09.08.459408 — microbiology — Posted on 2021-09-08
3091 Tafazzin deficiency in mouse mesenchymal stem cells potentiates their immunosuppression and impairs activated B lymphocyte immune function
Zegallai, H. M.; Abu-El-Rub, E.; Olayinka-Adefemi, F.; Cole, L. K.; Sparagna, G. C.; Marshall, A. J.; Hatch, G. M.
10.1101/2021.09.07.459330 — immunology — Posted on 2021-09-08
3092 TET1 controls Cxcl1 induction by DNA demethylation and promotes neutrophil recruitment during acute lung injury
SHUAI, K.; Yee, K.; SHUAI, R. W.; Huynh, C. A.; Niu, C.; Lee, H. R.; Lee, M.-s.; Wen, J.; Zou, J.; Wu, J.
10.1101/2021.09.07.459280 — immunology — Posted on 2021-09-08
3093 No substantial pre-existing B cell immunity against SARS-CoV-2 in healthy adults
Ercanoglu, M. S.; Gieselmann, L.; Daehling, S.; Poopalasingam, N.; Detmer, S.; Koch, M.; Korenkov, M.; Halwe, S.; Kluever, M.; Di Cristanziano, V.; Janicki, U. H.; Schlotz, M.; Worczinski, J.; Gathof, B.; Gruell, H.; Zehner, M.; Becker, S.; Vanshylla, K.; Kreer, C.; Klein, F.
10.1101/2021.09.08.459398 — immunology — Posted on 2021-09-08
3094 An individualized fMRI-based protocol to assess semantic memory in a heterogeneous multilingual population
Perquin, M.; Viswanathan, S.; Vaillant, M.; Risius, O.; Huiart, L.; Schmit, J.-C.; Diederich, N. J.; Fink, G. R.; Kukolja, J.
10.1101/2021.09.07.459272 — neuroscience — Posted on 2021-09-08
3099 Sex biases in cancer and autoimmune disease incidence are correlated across human tissues
Crawford, D. R.; Sinha, S.; Nair, N. U.; Ryan, B. M.; Barnholtz-Sloan, J. S.; Mount, S. M.; Erez, A.; Aldape, K.; Castle, P. E.; Rajagopal, P. S.; Day, C.-P.; Schäffer, A. A.; Ruppin, E.
10.1101/2021.09.07.459207 — cancer biology — Posted on 2021-09-08
3103 Micro-dissection and integration of long and short reads to create a robust catalog of kidney compartment-specific isoforms
Eksi, R.; Yi, D.; Li, H.; Godfrey, B.; Mathew, L. R.; OConnor, C. L.; Bitzer, M.; Kretzler, M.; Menon, R.; Guan, Y.
10.1101/2021.09.07.459298 — bioinformatics — Posted on 2021-09-08
3105 Honest cues contribute to male choice for female guarding in a herbivorous spider mite.
Goossens, S. F.; Mortier, F.; Parmentier, T.; Batsleer, F.; Van Leeuwen, T.; Wybouw, N.; Bonte, D.
10.1101/2021.09.07.459265 — animal behavior and cognition — Posted on 2021-09-08
3106 GABOLA: A Reliable Gap-Filling Strategy for de novo Chromosome-Level Assembly
Chuang, W.-H.; Cheng, H.-C.; Chang, Y.-J.; Fu, P.-Y.; Huang, Y.-C.; Hsieh, P.-H.; Chen, S.-H.; Lin, C.-Y.; Ho, J.-M.
10.1101/2021.09.07.459217 — genomics — Posted on 2021-09-08
3107 STAAR Workflow: A cloud-based workflow for scalable and reproducible rare variant analysis
Gaynor, S. M.; Westerman, K. E.; Ackovic, L. L.; Li, X.; Li, Z.; Manning, A. K.; Philippakis, A.; Lin, X.
10.1101/2021.09.07.456116 — genetics — Posted on 2021-09-08
3108 Simultaneous expression of UV and violet SWS1 opsins expands the visual palette in a group of freshwater snakes.
Hauzman, E.; Pierotti, M. E.; Bhattacharyya, N.; Tashiro, J. H.; Yovanovich, C. A.; Campos, P. F.; Ventura, D. F.; Chang, B.
10.1101/2021.09.07.459283 — evolutionary biology — Posted on 2021-09-08
3111 Characterization of Histone Lysine β-hydroxybutyrylation in bovine tissues, cells, and cumulus-oocyte complexes
Sangalli, J. R.; Nociti, R. P.; del Collado, M.; Sampaio, R. V.; da Silveira, J. C.; Perecin, F.; Smith, L. C.; Ross, P. J.; Meirelles, F. V.
10.1101/2021.09.07.459289 — developmental biology — Posted on 2021-09-08
3114 Selective activation of BK channels in small-headed dendritic spines suppresses excitatory postsynaptic potentials
Tazerart, S.; Blanchard, M. G.; Miranda-Rottmann, S.; Mitchell, D. E.; Pina, B. N.; Thomas, C. I.; Kamasawa, N.; Araya, R.
10.1101/2021.09.07.459293 — neuroscience — Posted on 2021-09-08
3123 Magnetic fluctuations affect circadian patterns of locomotor activity in zebrafish
Krylov, V. V.; Izvekov, E.; Pavlova, V. V.; Pankova, N. A.; Osipova, E. A.
10.1101/2021.09.08.459369 — physiology — Posted on 2021-09-08
3124 Transcriptional regulation of HSCs in Aging and MDS reveals DDIT3 as a Potential Driver of Transformation
Berastegui, N.; Ainciburu, M.; Romero, J. P.; Alfonso-Pierola, A.; Philippe, C.; Vilas-Zornoza, A.; San Martin, P.; Ordonez, R.; Alignani, D. O.; Sarvide, S.; Castro, L.; Lamo-Espinosa, J. M.; San-Julian, M.; Jimenez, T.; Lopez Cardenas, F.; Muntion, S.; Sanchez-Guijo, F.; Molero, A.; Montoro, J.; Tazon, B.; Serrano, G.; Diaz-Mazkiaran, A.; Hernaez, M.; Huerga, S.; Copley, F.; Rio-Machin, A.; Maurano, M. T.; Diez-Campelo, M.; Valcarcel, D.; Rouault-Pierre, K.; Lara-Astiaso, D.; Ezponda, T.; Prosper, F.
10.1101/2021.09.08.459384 — cancer biology — Posted on 2021-09-08
3125 Anterior Gradient-2 (AGR2) overexpression in colon cancer: a potential prognostic biomarker
Fessart, D.; Mahouche, I.; Brouste, V.; Velasco, V.; Soubeyran, I.; Soubeyran, P.; Pernot, S.; Chevet, E.; Evrard, S.; Robert, J.; Delom, F.
10.1101/2021.09.07.459258 — cancer biology — Posted on 2021-09-08
3127 A high throughput bispecific antibody discovery pipeline
Segaliny, A. I.; Jayaraman, J.; Chen, X.; Chong, J.; Luxon, R.; Fung, A.; Fu, Q.; Jiang, X.; Rivera, R.; Ma, X.; Ren, C.; Zimak, J.; Hedde, P. N.; Shang, Y.; Wu, G.; Zhao, W.
10.1101/2021.09.07.459213 — bioengineering — Posted on 2021-09-08
3134 Histone deacetylase inhibition reduces deleterious cytokine release induced by ingenol stimulation
Larragoite, E. T.; Nell, R. A.; Martins, L. J.; Barrows, L. R.; Planelles, V.; Spivak, A. M.
10.1101/193946 — microbiology — Posted on 2021-09-08
3138 Empirical estimates of the mutation rate for an alphabaculovirus
Boezen, D.; Ali, G.; Wang, M.; Wang, X.; van der Werf, W.; Vlak, J. M.; Zwart, M. P.
10.1101/2021.09.07.459225 — genetics — Posted on 2021-09-08
3140 Roles of cellular senescence in driving bone marrow adiposity in radiation-and aging-associated bone loss
Chandra, A.; Lagnado, A. B.; Farr, J. N.; Shleusner, M.; Monroe, D.; Hachfeld, C.; Passos, J.; Khosla, M.D, S.; Pignolo, R.
10.1101/2021.09.07.459232 — molecular biology — Posted on 2021-09-08
3141 Impact of Type II LRRK2 inhibitors on signalling and mitophagy
Tasegian, A.; Singh, F.; Ganley, I.; Reith, A. D.; Alessi, D. R.
10.1101/2021.05.21.445132 — neuroscience — Posted on 2021-09-08
3142 Primary tumor associated macrophages activate programs of invasion and dormancy in disseminating tumor cells.
Borriello, L.; Coste, A.; Sharma, V.; Karagiannis, G.; Lin, Y.; Wang, Y.; Ye, X.; Duran, C.; Chen, X.; Dalla, E.; Singh, D.; Oktay, M.; Condeelis, J.; Entenberg, D.
10.1101/2021.02.04.429798 — cancer biology — Posted on 2021-09-08
3143 High throughput measurement of Arabidopsis thaliana fitness traits using deep learning
Wang, P.; Meng, F.; Donaldson, P.; Horan, S.; Panchy, N. L.; Vischulis, E.; Winship, E.; Conner, J. K.; Krysan, P. J.; Shiu, S.-H.; Lehti-Shiu, M. D.
10.1101/2021.07.01.450758 — bioinformatics — Posted on 2021-09-08
3146 Production of offspring from azoospermic mice with meiotic failure: Precise biparental meiosis within halved oocytes
Ogonuki, N.; Kyogoku, H.; Hino, T.; Osawa, Y.; Fujiwara, Y.; Inoue, K.; Kunieda, T.; Mizuno, S.; Tateno, H.; Sugiyama, F.; Kitajima, T.; Ogura, A.
10.1101/2021.09.03.458818 — developmental biology — Posted on 2021-09-08
3148 Illuminating links between cis-regulators and trans-acting variants in the human prefrontal cortex
Liu, S.; Won, H.; Clarke, D.; Matoba, N.; Khullar, S.; Mu, Y.; Wang, D.; Gerstein, M.
10.1101/2021.09.07.459322 — genomics — Posted on 2021-09-07
3149 Lowland plant migrations into alpine ecosystems amplify soil carbon loss under climate warming
Walker, T. W. N.; Gavazov, K.; Guillaume, T.; Lambert, T.; Mariotte, P.; Routh, D.; Signarbieux, C.; Block, S.; Muenkemueller, T.; Nomoto, H.; Crowther, T. W.; Richter, A.; Buttler, A.; Alexander, J. M.
10.1101/2021.07.21.453211 — ecology — Posted on 2021-09-08
3150 Retrospective analysis of enhancer activity and transcriptome history
Boers, R.; Boers, J.; Tan, B.; Wassenaar, E.; Gonzalez Sanchez, E.; Sleddens, E.; Tenhagen, Y.; van Leeuwen, M.; Mulugeta, E.; Laven, J.; Creyghton, M.; Baarends, W. M.; van IJcken, W.; Gribnau, J.
10.1101/2021.09.07.459233 — developmental biology — Posted on 2021-09-08
3155 External drivers of BOLD signals non-stationarity
Ashourvan, A.; Pequito, S.; Bertolero, M.; Kim, J. Z.; Bassett, D. S.; Litt, B.
10.1101/2021.09.07.459325 — neuroscience — Posted on 2021-09-07
3156 Neurophysiological evidence for cognitive map formation during sequence learning
Stiso, J.; Lynn, C. W.; Kahn, A. E.; Rangarajan, V.; Szymula, K. P.; Archer, R.; Revell, A.; Stein, J. M.; Litt, B.; Davis, K. A.; Lucas, T. H.; Bassett, D. S.
10.1101/2021.09.07.459302 — neuroscience — Posted on 2021-09-07
3161 The response of three-dimensional pancreatic alpha and beta cell co-cultures to oxidative stress
Sthijns, M. M. J. P. E.; Rademakers, T.; Oosterveer, J.; Geuens, T.; van Blitterswijk, C. A.; LaPointe, V.
10.1101/2021.09.07.459320 — cell biology — Posted on 2021-09-07
3162 Differentially optimized cell-free buffer enables robust expression from unprotected linear DNA in exonuclease-deficient extracts
Batista, A. C.; Levrier, A.; Soudier, P.; Voyvodic, P.; Achmedov, T.; Reif-Trauttmansdorff, T.; DeVisch, A.; Gonsaud, M. C.; Faulon, J.-L.; Beisel, C.; Bonnet, J.; Kushwaha, M.
10.1101/2021.09.07.459228 — synthetic biology — Posted on 2021-09-07
3163 STUB1 is an intracellular checkpoint for interferon gamma sensing
Ng, S.; Lim, S.; Sim, A. C. N.; Mangadu, R.; Lau, A.; Zhang, C.; Bollinger Martinez, S.; Chandramohan, A.; Lim, U.-M.; Ho, S. S. W.; Chang, S. C.; Gopal, P.; Hong, L. Z.; Schwaid, A.; Fernandis, A. Z.; Loboda, A.; Li, C.; Phan, U.; Henry, B.; Partridge, A. W.
10.1101/2020.12.14.420539 — cancer biology — Posted on 2021-09-07
3167 Consequences of coupled barriers to gene flow for the build-up of genomic differentiation
Kunerth, H. D.; Bogdanowicz, S. M.; Searle, J. B.; Harrison, R. G.; Coates, B. S.; Kozak, G. M.; Dopman, E. B.
10.1101/2021.09.02.458401 — evolutionary biology — Posted on 2021-09-07
3169 Arg-tRNA synthetase links inflammatory metabolism to RNA splicing via nuclear condensates
Cui, H.; Diedrich, J. K.; Wu, D. C.; Lim, J. J.; Nottingham, R. M.; Moresco, J. J.; Yates, J. R.; Blencowe, B.; Lambowitz, A. M.; Schimmel, P.
10.1101/2021.09.07.459304 — molecular biology — Posted on 2021-09-07
3170 Non-canonical Staphylococcus aureus pathogenicity island repression
Miguel-Romero, L.; Alqasmi, M.; Bacarizo, J.; Tan, J.; Cogdell, R. J.; Byron, O.; Christie, G. E.; Marina, A.; Penades, J. R.
10.1101/2021.09.07.459249 — molecular biology — Posted on 2021-09-07
3172 Symbiotic bacterial community of Drosophila melanogaster changes with nutritional modifications of the diet but can alleviate negative effects on larval phenotypes
Bombin, A.; Cunneely, O.; Bombin, S.; Eickman, K.; Ruesy, A.; Cowan, R.; Myers, A.; Su, M.; Mosley, J. D.; Ferguson, J.; Reed, L. K.
10.1101/2021.09.07.458894 — microbiology — Posted on 2021-09-07
3174 24-nt phasiRNAs move from tapetal to meiotic cells in maize anthers
Zhou, X.; Huang, K.; Teng, C.; Batish, M.; Meyers, B. C.; Walbot, V.
10.1101/2021.08.24.457464 — plant biology — Posted on 2021-09-07
3175 R-loops between nascent pri-miRNAs and the encoding loci promote co-transcriptional processing of miRNAs in plants
Gonzalo, L.; Tossolini, I.; Gulanicz, T.; Cambiagno, D. A.; Kasprowicz-Maluski, A.; Smolinski, J. D.; Marquardt, S.; Szweykowska-Kulinska, Z.; Jarmolowski, A.; Manavella, P. A.
10.1101/2021.09.07.459282 — plant biology — Posted on 2021-09-07
3176 Discovery of signatures of fatal neonatal illness in vital signs using highly comparative time-series analysis
Niestroy, J.; Moorman, J. R.; Levinson, M. A.; Al Manir, S.; Clark, T. W.; Fairchild, K. D.; Lake, D. E.
10.1101/2021.03.26.437138 — bioinformatics — Posted on 2021-09-07
3178 Improved Docking of Protein Models by a Combination of Alphafold2 and ClusPro
Ghani, U.; Desta, I.; Jindal, A.; Khan, O.; Jones, G.; Kotelnikov, S.; Padhorny, D.; Vajda, S.; Kozakov, D.
10.1101/2021.09.07.459290 — bioinformatics — Posted on 2021-09-07
3180 Empirical estimates of the mutation rate for an alphabaculovirus
Boezen, D.; Alie, G.; Wang, M.; Wang, X.; van der Werf, W.; Vlak, J. M.; Zwart, M. P.
10.1101/2021.09.07.459225 — genetics — Posted on 2021-09-07
3182 Knockout of E-cadherin in adult mouse epithelium results in emphysema and airway disease
Ghosh, B.; Loube, J.; Thapa, S.; Capodanno, E.; Mahmud, S.; Girgis, M.; Chen, S.; Nishida, K.; Ying, L.; Swaby, C.; Wally, A.; Bhowmik, D. R.; Zaykaner, M. E.; Mitzner, W.; Sidhaye, V. K.
10.1101/2021.07.18.452342 — cell biology — Posted on 2021-09-07
3183 Local regulation of extracellular vesicle traffic by the synaptic endocytic machinery
Blanchette, C. R.; Scalera, A. L.; Harris, K. P.; Zhao, Z.; Koles, K.; Yeh, A.; Apiki, J. K.; Stewart, B. A.; Rodal, A. A.
10.1101/2021.08.04.454987 — cell biology — Posted on 2021-09-07
3184 OCT4 activates a Suv39h1-repressive antisense lncRNA to couple histone H3 Lysine 9 methylation to pluripotency
Bernard, L. D.; DUBOIS, A.; Heurtier, V.; Chervova, A.; Tachtsidi, A.; Gil, N.; Owens, N.; Vandormael-Pournin, S.; Ulitsky, I.; Cohen-Tannoudji, M.; Navarro, P.
10.1101/2021.09.07.459323 — molecular biology — Posted on 2021-09-07
3190 Epigenetic reprogramming of human macrophages by an intestinal pathogen
Bekere, I.; Huang, J.; Schnapp, M.; Rudolph, M.; Berneking, L.; Ruckdeschel, K.; Grundhoff, A.; Guenther, T.; Fischer, N.; Aepfelbacher, M.
10.1101/2021.09.07.459276 — microbiology — Posted on 2021-09-07
3191 Effects of bacterial lipopolysaccharide and Shiga Toxin on induced Pluripotent Stem Cell-derived Mesenchymal Stem Cells
Martire-Greco, D.; La Greca, A.; Castillo Montanez, L.; Biani, C.; Lombardi, A.; Birnberg-Weiss, F.; Norris, A.; Sacerdoti, F.; Amaral, M. M.; Rodrigues-Rodriguez, N.; Pittaluga, J. R.; Furmento, V. A.; Landoni, V. I.; Miriuka, S. G.; Luzzani, C. D.; Fernandez, G. C.
10.1101/2021.09.07.459335 — immunology — Posted on 2021-09-07
3193 Temporal irreversibility of neural dynamics as a signature of consciousness
de la Fuente, L. A.; Zamberlan, F.; Bocaccio, H.; Kringelbach, M. L.; Deco, G.; Sanz Perl, Y.; Tagliazucchi, E.
10.1101/2021.09.02.458802 — neuroscience — Posted on 2021-09-07
3194 Goal-centered representations in the human hippocampus
Crivelli-Decker, J.; Clarke, A.; Park, S.; Huffman, D.; Boorman, E.; Ranganath, C.
10.1101/2021.08.18.456881 — neuroscience — Posted on 2021-09-07
3199 Targeting metabolic adaptations in the breast cancer liver metastatic niche using dietary approaches to improve endocrine therapy efficacy
Zuo, Q.; Mogol, A. N.; Liu, Y.-J.; Casiano, A. S.; Chien, C.; Drnevich, J.; Imir, O. B.; Kulkoyluoglu-Cotul, E.; Park, N. H.; Shapiro, D. J.; Park, B. H.; Ziegler, Y.; Katzenellenbogen, B. S.; Aranda, E.; O'Neill, J. D.; Raghavendra, A. S.; Tripathy, D.; Madak-Erdogan, Z.
10.1101/2021.09.07.458711 — cancer biology — Posted on 2021-09-07
3202 Modular Fluorescent Nanoparticle DNA Probes for Detection of Peptides and Proteins
Stawicki, C. M.; Rinker, T. E.; Burns, M.; Tonapi, S. S.; Galimidi, R. P.; Anumala, D.; Robinson, J. K.; Klein, J. S.; Mallick, P.
10.1101/2021.07.30.454524 — bioengineering — Posted on 2021-09-07
3204 Bioengineering a Miniaturized In Vitro 3D Myotube Contraction Monitoring Chip For Modelization of Muscular Dystrophies
Rose, N.; Sonam, S.; Nguyen, T.; Grenci, G.; Bigot, A.; Muchir, A.; Ladoux, B.; Le Grand, F.; Trichet, L.
10.1101/2021.06.15.448543 — bioengineering — Posted on 2021-09-07
3212 Transendothelial migration induces differential migration dynamics of leukocytes in tissue matrix
van Steen, A. C. I.; Kempers, L.; Schoppmeyer, R.; Blokker, M.; Beebe, D. J.; Nolte, M. A.; van Buul, J. D.
10.1101/2021.09.02.458715 — cell biology — Posted on 2021-09-07
3213 In vitro discovery and optimization of a human monoclonal antibody that neutralizes neurotoxicity and lethality of cobra snake venom
Ledsgaard, L.; Laustsen, A. H.; Pus, U.; Wade, J.; Villar, P.; Boddum, K.; Slavny, P.; Masters, E. W.; Arias, A. S.; Oscoz, S.; Griffiths, D. T.; Luther, A. M.; Lindholm, M.; Leah, R. A.; Moeller, M. S.; Ali, H.; McCafferty, J.; Lomonte, B.; Gutierrez, J. M.; Karatt-Vellatt, A.
10.1101/2021.09.07.459075 — molecular biology — Posted on 2021-09-07
3217 Naturalistic hyperscanning with wearable magnetoencephalography
Holmes, N.; Rea, M.; Hill, R. M.; Boto, E.; Stuart, A.; Leggett, J.; Edwards, L. J.; Rhodes, N.; Shah, V.; Osborne, J.; Fromhold, T. M.; Glover, P. M.; Montague, P. R.; Brookes, M. J.; Bowtell, R. W.
10.1101/2021.09.07.459124 — neuroscience — Posted on 2021-09-07
3219 Guidelines for reliable and reproducible functional enrichment analysis
Wijesooriya, K.; Jadaan, S. A.; Perera, K. L.; Kaur, T.; Ziemann, M.
10.1101/2021.09.06.459114 — bioinformatics — Posted on 2021-09-07
3233 Entrectinib - a SARS-CoV-2 inhibitor in Human Lung Tissue (HLT) cells
Peralta-Garcia, A.; Torrens-Fontanals, M.; Stepniewski, T. M.; Grau-Exposito, J.; Perea, D.; Ayinampudi, V.; Waldhoer, M.; Zimmermann, M.; Buzon, M. J.; Genesca, M.; Selent, J.
10.1101/2021.09.07.459123 — cell biology — Posted on 2021-09-07
3235 Ineffective neutralization of the SARS-CoV-2 Mu variant by convalescent and vaccine sera
Uriu, K.; Kimura, I.; Shirakawa, K.; Takaori-Kondo, A.; Nakada, T.-a.; Kaneda, A.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Nakagawa, S.; Sato, K.
10.1101/2021.09.06.459005 — microbiology — Posted on 2021-09-07
3236 Increased neutralization of SARS-CoV-2 Delta variant by nanobody (Nb22) and the structural basis
Wu, X.; Wang, Y.; Cheng, L.; Zhu, L.; Ma, S.; Huang, B.; Xu, S.; Shi, H.; Liu, L.; Nawaz, W.; Ye, S.; Wu, Z.
10.1101/2021.09.06.459055 — microbiology — Posted on 2021-09-07
3237 The vaccinia-based Sementis Copenhagen Vector COVID-19 vaccine induces broad and durable cellular and humoral immune responses
Eldi, P.; Cooper, T. H.; Prow, N. A.; Liu, L.; Heinemann, G. K.; Zhang, V. J.; Trinidad, A. D.; Guzman-Genuino, R. M.; Wulff, P.; Hobbs, L. M.; Diener, K. R.; Hayball, J. D.
10.1101/2021.09.06.459206 — immunology — Posted on 2021-09-07
3239 Molecular phylogeny of fucoxanthin-chlorophyll a/c proteins from Chaetoceros gracilis and Lhcq/Lhcf diversity
Kumazawa, M.; Nishide, H.; Nagao, R.; Inoue-Kashino, N.; Shen, J.-R.; Nakano, T.; Uchiyama, I.; Kashino, Y.; Ifuku, K.
10.1101/2021.09.06.459020 — plant biology — Posted on 2021-09-07
3242 Both Simulation and Sequencing Data Reveal Multiple SARS-CoV-2 Variants Coinfection in COVID-19 Pandemic
Li, Y.; Jiang, Y.; Li, Z.; Yu, Y.; Chen, J.; Jia, W.; Ng, Y. K.; Ye, F.; Shen, B.; Li, S. C.
10.1101/2021.09.06.459196 — bioinformatics — Posted on 2021-09-07
3243 Dissecting the roles of Haspin and VRK1 in Histone H3 threonine-3 phosphorylation during mitosis
Cartwright, T. N.; Harris, R. J.; Meyer, S. K.; Watson, N. A.; Tan, C.; Wang, F.; Higgins, J. M. G.
10.1101/2021.09.07.459242 — cell biology — Posted on 2021-09-07
3244 Inhibition of HIV-1 immune modulation by small molecules targeting viral Nef-host CD80 interface
Sharma, A. U.; Sharma, S.; Arumugam, G.; Nair, A. P.; Ambala, S.; Munagala, G.; Yempalla, K. R.; Munjal, A.; Rajkumar, S.; Kamariah, N.; Ramanathan, S.; Saiyed, T.; Venkitaraman, A. R.; Singh, P. P.; Vishwakarma, R.; Mayor, S.; Karumbati, A. S.
10.1101/2021.09.07.459239 — microbiology — Posted on 2021-09-07
3245 CRISPR screens identify gene targets and drug repositioning opportunities at breast cancer risk loci
Tuano, N. K.; Beesley, J.; Manning, M.; Shi, W.; Malver-Ortega, L.; Paynter, J.; Black, D.; Civitarese, A.; McCue, K.; Hatzipantelis, A.; Hillman, K.; Kaufmann, S.; Sivakumaran, H.; Polo, J. M.; Reddel, R.; Band, V.; French, J. D.; Edwards, S. L.; Powell, D.; Chenevix-Trench, G.; Rosenbluh, J.
10.1101/2021.09.07.459221 — cancer biology — Posted on 2021-09-07
3246 Molecular organization and mechanics of single vimentin filaments revealed by super-resolution imaging
Vicente, F. N.; Lelek, M.; Tinevez, J.-Y.; Tran, Q. D.; Pehau-Arnaudet, G.; Zimmer, C.; Etienne-Manneville, S.; Giannone, G.; Leduc, C.
10.1101/2021.09.07.459174 — biophysics — Posted on 2021-09-07
3247 CRISPR-Cas9 bends and twists DNA to read its sequence
Cofsky, J. C.; Soczek, K. M.; Knott, G. J.; Nogales, E.; Doudna, J. A.
10.1101/2021.09.06.459219 — biochemistry — Posted on 2021-09-07
3248 BMSC-Derived Exosomal MiRNAs Can Modulate Bone Restoration in Diabetic Rats with Femoral Defects
Guo, Z.; Wang, N.; Liu, X. C.; Tang, Z.; Wei, X. H.; Dong, H.; Liu, Y. C.; Wu, H.; Wu, Z. G.; Li, X. K.; Ma, X.
10.1101/2021.09.07.459238 — cell biology — Posted on 2021-09-07
3250 Myelin speeds cortical oscillations by consolidating phasic parvalbumin-mediated inhibition
Dubey, M.; Pascual-Garcia, M.; Helmes, K.; Wever, D.; Hamada, M. S.; Kushner, S. A.; Kole, M. H. P.
10.1101/2021.09.07.459122 — neuroscience — Posted on 2021-09-07
3252 Genetic, metabolic, and molecular insights into the diverse outcomes of diet-induced obesity in mice
Bachmann, A. M.; Morel, J.-D. H.; El Alam, G.; Rodriguez-Lopez, S.; de lima, T. I.; Goeminne, L. J. E.; Benegiamo, G.; Bou Sleiman, M. S.; Auwerx, J.
10.1101/2021.09.02.458729 — bioinformatics — Posted on 2021-09-07
3253 Consequences of coupled barriers to gene flow for the build-up of genomic differentiation
Kunerth, H. D.; Bogdanowicz, S. M.; Searle, J. B.; Harrison, R. G.; Coates, B. S.; Kozak, G. M.; Dopman, E. B.
10.1101/2021.09.02.458401 — evolutionary biology — Posted on 2021-09-07
3255 Subacute Inhalation of Ultrafine Particulate Matter Triggers Inflammation Without Altering Amyloid Beta Load in 5xFAD mice.
Saveleva, L.; Vartiainen, P.; Gorova, V.; Chew, S.; Belaya, I.; Konttinen, H.; Zucchelli, M.; Korhonen, P.; Kaartinen, E.; Kortelainen, M.; Lamberg, H.; Sippula, O.; Malm, T.; Jalava, P. I.; Kanninen, K. M.
10.1101/2021.09.07.459017 — neuroscience — Posted on 2021-09-07
3258 SC-MEB: spatial clustering with hidden Markov random field using empirical Bayes
Yang, Y.; Shi, X.; Liu, W.; Zhou, Q.; Lau, M. C.; Lim, J. C. T.; Sun, L.; Yeong, J.; Liu, J.
10.1101/2021.06.05.447181 — genomics — Posted on 2021-09-07
3264 A high resolution single molecule sequencing-based Arabidopsis transcriptome using novel methods of Iso-seq analysis
Zhang, R.; Kuo, R.; Coulter, M.; Calixto, C. P. G.; Entizne, J. C.; Guo, W.; Marquez, Y.; Milne, L.; Riegler, S.; Matsui, A.; Tanaka, M.; Harvey, S.; Yubang, G.; Wiebner-Kroh, T.; Crespi, M.; Denby, K.; Hur, A. b.; Huq, E.; Jantsch, M. F.; Jarmolowski, A.; Koester, T.; Laubinger, S.; Li, Q. Q.; Gu, L.; Seki, M.; Staiger, D.; Sunkar, R.; Szweykowska-Kulinska, Z.; Tu, S.-L.; Wachter, A.; Waugh, R.; Xiong, L.; Zhang, X.-N.; Reddy, A. S. N.; Barta, A.; Kalyna, M.; Brown, J. W.
10.1101/2021.09.02.458763 — plant biology — Posted on 2021-09-07
3265 The histone variant macroH2A1.1 regulates RNA Polymerase II paused genes within defined chromatin interaction landscapes.
Recoules, L.; Heurteau, A.; Raynal, F.; Karasu, N.; Moutahir, F.; Bejjani, F.; Jariel-Encontre, I.; Cuvier, O.; Sexton, T.; Lavigne, A.-C.; Bystricky, k.
10.1101/2020.01.29.924704 — genomics — Posted on 2021-09-07
3267 Molecular coevolution of nuclear and nucleolar localization signals inside basic domain of HIV-1 Tat
Kurnaeva, M. A.; Zalevsky, A. O.; Arifulin, E. A.; Lisitsyna, O. M.; Tvorogova, A. V.; Shubina, M. Y.; Bourenkov, G. P.; Tikhomirova, M. A.; Potashnikova, D. M.; Kachalova, A. I.; Musinova, Y. R.; Golovin, A. V.; Vassetzky, Y. S.; Sheval, E. V.
10.1101/2021.04.20.440437 — evolutionary biology — Posted on 2021-09-07
3268 Synthetic deconstruction of hunchback regulation by Bicoid
Fernandes, G.; Tran, H.; Andrieu, M.; Diaw, Y.; Perez Romero, C.; Fradin, C.; Coppey, M.; Walczak, A. M.; Dostatni, N.
10.1101/2021.09.06.459125 — developmental biology — Posted on 2021-09-07
3269 Automatic end-to-end analysis of high-throughput in vitro cell culture screening by HTSplotter
Nunes, C.; Anckaert, J.; De Vloed, F.; De Wyn, J.; Durinck, K.; Vandesompele, J.; Speleman, F.; Vermeirssen, V.
10.1101/2021.09.06.459128 — bioinformatics — Posted on 2021-09-07
3272 Leaf area index estimation of even-aged oak (Quercus petraea) forests using in situ stand dendrometric parameters
Maxime, B.; Francois, C.; Lebourgeois, F.; Seynave, I.; Ningre, F.; Vincent, G.; Korboulewsky, N.; Perot, T.; Perret, S.; Calas, A.; Dufrene, E.
10.1101/2021.08.05.454476 — ecology — Posted on 2021-09-07
3273 Production of offspring from azoospermic mice with meiotic failure: Precise biparental meiosis within halved oocytes
Ogonuki, N.; Kyogoku, H.; Hino, T.; Osawa, Y.; Fujiwara, Y.; Inoue, K.; Kunieda, T.; Mizuno, S.; Tateno, H.; Sugiyama, F.; Kitajima, T.; Ogura, A.
10.1101/2021.09.03.458818 — developmental biology — Posted on 2021-09-07
3275 Temporal dynamics of neural responses in human visual cortex
Groen, I. I. A.; Piantoni, G.; Montenegro, S.; Flinker, A.; Devore, S.; Devinsky, O.; Doyle, W.; Ramsey, N.; Petridou, N.; Winawer, J. A.
10.1101/2021.08.08.455547 — neuroscience — Posted on 2021-09-07
3277 Reversible supramolecular assembly of the anti-microbial peptide plectasin into helical non-amyloid fibrils
Pohl, C.; Effantin, G.; Kandiah, E.; Meier, S.; Zeng, G.; Streicher, W.; Peters, G. H.; Schoehn, G.; Mueller-Dieckmann, C.; Noergaard, A.; Harris, P.
10.1101/2021.09.06.458672 — biophysics — Posted on 2021-09-07
3279 Synthetic deconstruction of hunchback regulation by Bicoid
Fernandes, G.; Tran, H.; Andrieu, M.; Diaw, Y.; Perez Romero, C.; Fradin, C.; Coppey, M.; Walczak, A. M.; Dostatni, N.
10.1101/2021.09.06.459125 — developmental biology — Posted on 2021-09-07
3281 Time scale separation of information processing between sensory and associative regions
Sorrentino, P.; Rabuffo, G.; Rucco, R.; Baselice, F.; Troisi Lopez, E.; Liparoti, M.; Quarantelli, M.; Sorrentino, G.; Bernard, C.; Jirsa, V.
10.1101/2020.10.23.350322 — neuroscience — Posted on 2021-09-07
3282 Intrusive Experiences In Post-Traumatic Stress Disorder: Treatment Response Induces Changes In The Effective Connectivity Of The Anterior Insula
Leroy, A.; Very, E.; Birmes, P.; Szaffarczyk, S.; Lopes, R.; Faure, C.; Duhem, S.; Grandgenevre, P.; Warembourg, F.; Vaiva, G.; Jardri, R.
10.1101/2020.10.01.319269 — neuroscience — Posted on 2021-09-07
3284 Genomic evidence for inbreeding depression and purging of deleterious genetic variation in Indian tigers
Khan, A.; Patel, K.; Shukla, H.; Viswanathan, A.; van der Valk, T.; Borthakur, U.; Nigam, P.; Zachariah, A.; Jhala, Y.; Kardos, M.; Ramakrishnan, U.
10.1101/2021.05.18.444660 — evolutionary biology — Posted on 2021-09-06
3292 Mapping of a N-terminal α-helix domain required for human PINK1 stabilisation, Serine228 autophosphorylation and activation in cells
Kakade, P.; Ojha, H.; Raimi, O.; Shaw, A.; Waddell, A.; Ault, J.; Burel, S.; Brockmann, K.; Kumar, A.; Ahanger, M.; Krysztofinska, E.; Macartney, T.; Bayliss, R.; Fitzgerald, J. C.; Muqit, M.
10.1101/2021.09.06.459138 — biochemistry — Posted on 2021-09-06
3302 The 14-3-3 Proteins Bmh1 and Bmh2 Are Key Regulators of Meiotic Commitment
Gavade, J.; Puccia, C. M.; Herod, S. G.; Trinidad, J.; Berchowitz, L. E.; Lacefield, S.
10.1101/2021.09.06.459189 — cell biology — Posted on 2021-09-06
3304 ASFV pD345L protein negatively regulates NF-kB signaling through inhibiting IKK kinase activity
Qian, Y.; Chen, h.; Wu, X.; Wang, Z.; Gao, X.; Lv, J.; Hu, Y.; Jung, Y.-S.; Zhu, S.; Dai, J.
10.1101/2021.09.06.459096 — microbiology — Posted on 2021-09-06
3307 Organization and engagement of a prefrontal-olfactory network during olfactory selective attention
Cansler, H. L.; in 't Zandt, E. E.; Carlson, K. S.; Khan, W. T.; Ma, M.; Wesson, D. W.
10.1101/2021.09.04.458996 — neuroscience — Posted on 2021-09-06
3308 Microglia drive pockets of neuroinflammation in middle age
Moca, E. N.; Lecca, D.; Hope, K. T.; Tweedie, D.; Sidhu, S.; Masukawa, L.; Sitoy, H.; Mathew, R.; Saban, D.; Greig, N. H.; De Biase, L. M.
10.1101/2021.02.02.429070 — neuroscience — Posted on 2021-09-06
3310 A high resolution single molecule sequencing-based Arabidopsis transcriptome using novel methods of Iso-seq analysis
Zhang, R.; Kuo, R.; Coulter, M.; Calixto, C. P. G.; Entizne, J. C.; Guo, W.; Marquez, Y.; Milne, L.; Riegler, S.; Matsui, A.; Tanaka, M.; Harvey, S.; Yubang, G.; Wiebner-Kroh, T.; Crespi, M.; Denby, K.; Hur, A. b.; Huq, E.; Jantsch, M. F.; Jarmolowski, A.; Koester, T.; Laubinger, S.; Li, Q. Q.; Gu, L.; Seki, M.; Staiger, D.; Sunkar, R.; Szweykowska-Kulinska, Z.; Tu, S.-L.; Wachter, A.; Waugh, R.; Xiong, L.; Zhang, X.-N.; Reddy, A. S. N.; Barta, A.; Kalyna, M.; Brown, J. W.
10.1101/2021.09.02.458763 — plant biology — Posted on 2021-09-06
3312 Serine Starvation Silences Estrogen Receptor Signaling through Histone Hypoacetylation
Li, A. M.; Li, Y.; He, B.; Ramirez, Y.; Jiang, H.; Zhou, M.-N.; Lu, C.; Gruber, J. J.; Rankin, E. B.; Ye, J.
10.1101/2021.09.05.459037 — cancer biology — Posted on 2021-09-06
3313 Automatic end-to-end analysis of high-throughput in vitro cell culture screening by HTSplotter
Nunes, C.; Anckaert, J.; De Vloed, F.; De Wyn, J.; Durinck, K.; Vandesompele, J.; Speleman, F.; Vermeirssen, V.
10.1101/2021.09.06.459128 — bioinformatics — Posted on 2021-09-06
3314 Network-aware reaction pattern recognition reveals regulatory signatures of mitochondrial dysfunction
Berg, J. A.; Zhou, Y.; Ouyang, Y.; Waller, T. C.; Cluntun, A. A.; Conway, M. E.; Nowinski, S. M.; Van Ry, T.; George, I.; Cox, J. E.; Wang, B.; Rutter, J.
10.1101/2020.06.25.171850 — biochemistry — Posted on 2021-09-06
3316 Genome-wide association mapping of ethanol sensitivity in the Diversity Outbred mouse population
Parker, C. C.; Philip, V.; Gatti, D. M.; Kasparek, S.; Kreuzman, A.; Kuffler, L.; Mansky, B.; Masneuf, S.; Sharif, K.; Sluys, E.; Taterra, D.; Taylor, W. M.; Thomas, M.; Polesskaya, O.; Palmer, A. A.; Holmes, A.; Chesler, E.
10.1101/2021.09.06.459155 — genetics — Posted on 2021-09-06
3317 Genome-wide association study of musical beat synchronization demonstrates high polygenicity
Niarchou, M.; Gustavson, D. E.; Sathirapongsasuti, J. F.; Anglada-Tort, M.; Eising, E.; Bell, E.; McArthur, E.; Straub, P.; The 23andMe Research Team, ; McAuley, J. D.; Capra, J. A.; Ullen, F.; Creanza, N.; Mosing, M. A.; Hinds, D.; Davis, L. K.; Jacoby, N.; Gordon, R. L.
10.1101/836197 — genetics — Posted on 2021-09-06
3318 Experimental evolution of a pheromone signal
Blankers, T.; Fruitet, E.; Burdfield-Steel, E.; Groot, A. T.
10.1101/2021.09.06.459111 — evolutionary biology — Posted on 2021-09-06
3321 Dominant carnivore loss benefits native avian and invasive mammalian scavengers
Fielding, M. W.; Cunningham, C. X.; Buettel, J. C.; Stojanovic, D.; Jones, M. E.; Brook, B. W.
10.1101/2021.09.06.459188 — ecology — Posted on 2021-09-06
3325 Therapeutic activation of virus-specific resident memory T cells within the glioblastoma microenvironment
Ning, J.; Gavil, N.; Wu, S.; Wijeyesinghe, S.; Weyu, E.; Ma, J.; Li, M.; Grigore, F.-N.; Dhawan, S.; Skorput, A. G. J.; Musial, S. C.; Chen, C. C.; Masopust, D.; Rosato, P. C.
10.1101/2021.09.06.458939 — immunology — Posted on 2021-09-06
3327 An unconventional GABAergic circuit differently controls pyramidal neuron activity in two visual cortical areas via endocannabinoids
Montmerle, M.; Koukouli, F.; Aguirre, A.; Peixoto, J.; Choudhary, V.; De Brito Van Velze, M.; Varilh, M.; Julio-Kalajzic, F.; Allene, C.; Mendez, P.; Marsicano, G.; Schlueter, O.; Rebola, N.; Bacci, A.; Lourenco, J.
10.1101/2021.09.06.459113 — neuroscience — Posted on 2021-09-06
3329 A subset of nucleus accumbens neurons receiving dense and functional prelimbic cortical input are required for cocaine seeking
Siemsen, B. M.; Barry, S. M.; Vollmer, K.; Green, L. M.; Brock, A. G.; Westphal, A. M.; King, R. A.; DeVries, D. M.; Otis, J. M.; Cowan, C. W.; Scofield, M. D.
10.1101/2021.09.03.458762 — neuroscience — Posted on 2021-09-06
3332 Ascertaining cells' synaptic connections and RNA expression simultaneously with massively barcoded rabies virus libraries
Saunders, A.; Huang, K. W.; Vondrak, C.; Hughes, C.; Smolyar, K.; Sen, H.; Philson, A. C.; Nemesh, J.; Wysoker, A.; Kashin, S.; Sabatini, B. L.; McCarroll, S. A.
10.1101/2021.09.06.459177 — neuroscience — Posted on 2021-09-06
3334 Impaired photoprotection in Phaeodactylum tricornutum KEA3 mutants reveals the proton regulatory circuit of diatoms light acclimation.
Seydoux, C.; Storti, M.; Giovagnetti, V.; Matuszynska, A.; Guglielmino, E.; Zhao, X.; Giustini, C.; Pan, Y.; Angulo, J.; Ruban, A. V.; Hu, H.; Bailleul, B.; Courtois, F.; Allorent, G.; Finazzi, G.
10.1101/2021.09.06.459119 — plant biology — Posted on 2021-09-06
3335 Drug targeting to sites of oxidative stress using the Baeyer-Villiger reaction
Avery, T. D.; Li, J.; Turner, D. J. L.; Cherry, F. R.; Ur Rasheed, M. S.; Aguilar, C.; Shepherd, A. J.; Yu, J.; Grace, P. M.; Abell, A. D.
10.1101/2021.09.03.458872 — pharmacology and toxicology — Posted on 2021-09-06
3337 Glycoproteogenomics characterizes the CD44 splicing code driving bladder cancer invasion
gaiteiro, c.; Soares, J.; Relvas Santos, M.; Peixoto, A.; Ferreira, D.; Brandao, A.; Fernandes, E.; Azevedo, R.; Paulo, P.; Palmeira, C.; Lima, L.; Freitas, R.; Miranda, A.; Osorio, H.; Silva, A. M.; Prieto, J.; Lara Santos, L.; Ferreira, J. A.
10.1101/2021.09.04.458979 — cancer biology — Posted on 2021-09-06
3341 Ecology dictates the value of memory for foraging bees
Pull, C. D.; Petkova, I.; Watrobska, C.; Pasquier, G.; Pere Fernandez, M.; Leadbeater, E.
10.1101/2021.09.06.458851 — animal behavior and cognition — Posted on 2021-09-06
3342 Sequence conservation and structural features that are common within TRP channels
Cabezas-Bratesco, D.; Colenso, C. K.; Zavala, K.; Granata, D.; Carnevale, V.; Opazo, J. C.; Brauchi, S. E.
10.1101/2021.09.06.459056 — evolutionary biology — Posted on 2021-09-06
3344 The NDNF-like factor Nord is a Hedgehog-induced extracellular BMP modulator that regulates Drosophila wing patterning and growth
Yang, S.; Wu, X.; Daoutidou, E. I.; Zhang, Y.; Shimell, M.; Chuang, K.-H.; Peterson, A. J.; O'Connor, M. B.; Zheng, X.
10.1101/2021.09.06.459106 — developmental biology — Posted on 2021-09-06
3345 Synthetic deconstruction of hunchback regulation by Bicoid
Fernandes, G.; Tran, H.; Andrieu, M.; Diaw, Y.; Perez Romero, C.; Fradin, C.; Coppey, M.; Walczak, A. M.; Dostatni, N.
10.1101/2021.09.06.459125 — developmental biology — Posted on 2021-09-06
3347 The second lineage differentiation of bovine embryos fails in the absence of OCT4/POU5F1
Simmet, K.; Kurome, M.; Zakhartchenko, V.; Reichenbach, H.-D.; Springer, C.; Baehr, A.; Blum, H.; Philippou-Massier, J.; Wolf, E.
10.1101/2021.09.06.459107 — developmental biology — Posted on 2021-09-06
3348 Wnt signaling rescues amyloid beta induced stem cell loss
Kaur, P.; Chua, E. H. Z.; Lim, W. K.; Harmston, N.; Tolwinski, N. S.
10.1101/2021.09.06.459094 — cell biology — Posted on 2021-09-06
3349 eIF6 rebinding dynamically couples ribosome maturation and translation
Jaako, P.; Faille, A.; Tan, S.; Wong, C. C.; Escudero-Urquijo, N.; Castro-Hartmann, P.; Wright, P.; Hilcenko, C.; Adams, D.; Warren, A.
10.1101/2021.09.06.459071 — cell biology — Posted on 2021-09-06
3352 Mechanistic dissection of global proteomic changes in rats with heart failure and preserved ejection fraction
Soetkamp, D.; Binek, A.; Gallet, R.; de Couto, G.; Kilfoil, P.; Mostafa, R.; Venkatraman, V.; Holewinski, R.; Bradshaw, A. D.; Goldhaber, J.; Zile, M. R.; Marban, E.; Van Eyk, J. E.
10.1101/2021.09.06.456608 — molecular biology — Posted on 2021-09-06
3353 Chaos in small microbial communities
Karkaria, B. D.; Manhart, A.; Fedorec, A. J. H.; Barnes, C. P.
10.1101/2021.09.06.459097 — microbiology — Posted on 2021-09-06
3355 Mitochondrial sirtuin TcSir2rp3 affects TcSODA activity and oxidative stress response in Trypanosoma cruzi
dos Santos Moura, L.; Santana Nunes, V.; Gomes, A. A. S.; de Castro Nascimento Sousa, A. C.; Fontes, M. R. M.; Schenkman, S.; Moretti, N. S.
10.1101/2021.09.06.458705 — microbiology — Posted on 2021-09-06
3356 Viral tolerance in Aedes aegypti relies on the negative cooperativity between Toll5A and the cytokine ligand Spz1C
Saucereau, Y.; Wilson, T. H.; Moncrieffe, M. C.; Hardwick, S. W.; Chirgadze, D. Y.; Marcaida, M. J.; Gay, N. J.; Gangloff, M.
10.1101/2021.09.06.459066 — immunology — Posted on 2021-09-06
3357 Inhibition of the SHP-1 activity by PKC-θ regulates NK cell activation threshold and cytotoxicity
Barda-Saad, M.; Ben-Shmuel, A.; Sabag, B.; Biber, G.; Puthenveetil, A.; Levy, M.; Jubany, T.; Joseph, N.; Matalon, O.; Kivelevitz, J.
10.1101/2021.09.06.459131 — immunology — Posted on 2021-09-06
3358 Analysis of Rod/Cone Gap Junctions from the Reconstruction of Mouse Photoreceptor Terminals
Massey, S.; Ishibashi, M.; Keung, J.; Morgans, C. W.; Aicher, S.; Carroll, J.; Singer, J. H.; Jia, L.; Li, W.; Fahrenfort, I.; Ribelayga, C.
10.1101/2021.09.06.459091 — neuroscience — Posted on 2021-09-06
3359 Behavioral state tunes mouse vision to ethological features through pupil dilation
Franke, K.; Willeke, K. F.; Ponder, K.; Galdamez, M.; Muhammad, T.; Patel, S.; Froudarakis, E.; Reimer, J.; Sinz, F.; Tolias, A.
10.1101/2021.09.03.458870 — neuroscience — Posted on 2021-09-06
3366 The landscape of toxic intermediates in the metabolic networks of pathogenic fungi reveals targets for antifungal drugs
Ewald, J.; Jansen, P. M.; Brunke, S.; Hiller, D.; Luther, C. H.; Gonzalez-Diaz, H.; Dittrich, M. T.; Fleissner, A.; Hube, B.; Schuster, S.; Kaleta, C.
10.1101/2021.09.05.459012 — systems biology — Posted on 2021-09-06
3368 Community science designed ribosomes with beneficial phenotypes
Kruger, A.; Watkins, A. M.; Wellington-Oguri, R.; Romano, J.; Kofman, C.; DeFoe, A.; Kim, Y.; Anderson-Lee, J.; Fisker, E.; Townley, J.; Eterna participants, ; d'Aquino, A. E.; Das, R.; Jewett, M. C.
10.1101/2021.09.05.458952 — synthetic biology — Posted on 2021-09-06
3371 An evolutionarily ancient Fatty Acid Desaturase is required for the synthesis of hexadecatrienoic acid, which is the main source of the bioactive jasmonate in Marchantia polymorpha
Soriano, G.; Kneeshaw, S.; Jimenez-Aleman, G. H.; Zamarreno, A. M.; Franco-Zorrilla, J. M.; Rey-Stolle, M. F.; Barbas, C.; Garcia-Mina, J. M.; Solano, R.
10.1101/2021.09.06.459162 — plant biology — Posted on 2021-09-06
3373 Rest/Stress Myocardial Perfusion Imaging by Positron Emission Tomography with 18F-Flurpiridaz: A Feasibility Study in Mice
Bengs, S.; Warnock, G. I.; Portmann, A.; Mikail, N.; Rossi, A.; Ahmed, H.; Etter, D.; Gisler, L.; Jie, C.; Meisel, A.; Keller, C.; Schibli, R.; Mu, L.; Buechel, R. R.; Kaufmann, P. A.; Ametamey, S. M.; Gebhard, C.; Haider, A.
10.1101/2021.09.05.459034 — physiology — Posted on 2021-09-06
3374 Actions of camptothecin derivatives on larvae and adults of the arboviral vector Aedes aegypti
Partridge, F. A.; Poulton, B. C.; Lake, M. A. I.; Lees, R. A.; Mann, H.-J.; Lycett, G. J.; Sattelle, D. B.
10.1101/2021.09.06.458863 — pharmacology and toxicology — Posted on 2021-09-06
3377 The Sec61 translocon is a therapeutic vulnerability in Multiple Myeloma
Domenger, A.; Choisy, C.; Baron, L.; Mayau, V.; Deriano, L.; Arnulf, B.; Bories, J.-C.; Dadaglio, G.; Demangel, C.
10.1101/2021.09.05.459026 — cancer biology — Posted on 2021-09-06
3378 Chromatin accessibility combined with enhancer clusters activation mediates heterogeneous response to dexamethasone in myeloma cells
GABORIT, V.; CRUARD, J.; Guerin-Charbonnel, C.; Derrien, J.; Alberge, J.-B.; Douillard, E.; Roi, N.; Devic, M.; Campion, L.; Westermann, F.; Moreau, P.; Herrmann, C.; Bourdon, J.; Magrangeas, F.; Minvielle, S.
10.1101/2021.09.06.459068 — cancer biology — Posted on 2021-09-06
3379 SETDB1 Fuels the Lung Cancer Phenotype by Modulating Epigenome, 3D Genome Organization and Chromatin Mechanical Properties
Zakharova, V.; Magnitov, M.; Del-Maestro, L.; Ulianov, S.; Glentis, A.; Ulyanik, B.; Williart, A.; Karpukhina, A.; Demidov, O.; Joliot, V.; Vassetzky, Y.; Mege, R.-M. V.; Piel, M.; Razin, S.; Ait-Si-Ali, S.
10.1101/2021.09.06.459062 — cancer biology — Posted on 2021-09-06
3380 USP28 enables oncogenic transformation of respiratory cells and its inhibition potentiates molecular therapy targeting mutant EGFR, BRAF and PI3K.
Prieto-Garcia, C.; Hartmann, O.; Reissland, M.; Braun, F.; Bozkurt, S.; Fuss, C. T.; Schuelein-Voelk, C.; Buchberger, A.; Calzado, M. A.; Rosenfeldt, M. T.; Dikic, I.; Muench, C.; Diefenbacher, M. E.
10.1101/2021.09.06.459088 — cancer biology — Posted on 2021-09-06
3381 Immunosuppression and Outcomes in Acute Myeloid Leukemia
Ferraro, F.; Miller, C.; Christensen, K.; Helton, N. M.; O'Laughlin, M.; Fronick, C. C.; Fulton, R. S.; Kohlschmidt, J.; Eisfeld, A.-K.; Bloomfield, C. D.; Ramakrishnan, S. M.; Day, R. B.; Wartman, L. D.; Uy, G. L.; Welch, J. S.; Christopher, M. J.; Heath, S. E.; Baty, J. D.; Schuelke, M. J.; Payton, J. E.; Spencer, D. H.; Rettig, M. P.; Link, D. C.; Walter, M. J.; Peter, W.; DiPersio, J. F.; Ley, T. J.
10.1101/2021.09.03.458879 — cancer biology — Posted on 2021-09-06
3389 PIPENN: Protein Interface Prediction with an Ensemble of Neural Nets
Stringer, B.; De Ferrante, H.; Abeln, S.; Heringa, J.; Feenstra, K. A. A.; Haydarlou, R.
10.1101/2021.09.03.458832 — bioinformatics — Posted on 2021-09-06
3395 Biochemical characterization of a human septin octamer
Fischer, M.; Frank, D.; Roesler, R.; Johnsson, N.; Gronemeyer, T.
10.1101/2021.09.06.459054 — biochemistry — Posted on 2021-09-06
3396 HLA class II mediates type 1 diabetes risk by anti-insulin repertoire selection
Rubio Garcia, A.; Paterou, A.; Lee, M.; Slawinski, H.; Ferreira, R.; Landry, L. G.; Trzupek, D.; Teyton, L.; Szypowska, A.; Wicker, L. S.; Nakayama, M.; Todd, J. A.; Pekalski, M. L.
10.1101/2021.09.06.458974 — genomics — Posted on 2021-09-06
3399 Selective signatures and high genome-wide diversity in traditional Brazilian manioc (Manihot esculenta Crantz) varieties
Alves-Pereira, A.; Zucchi, M. I.; Clement, C. R.; Viana, J. P. G.; Pinheiro, J. B.; Veasey, E. A.; de Souza, A. P.
10.1101/2021.09.06.459170 — genetics — Posted on 2021-09-06
3400 Genetic epidemiology of blood type, disease and trait variants, and genome-wide genetic diversity in over 11,000 domestic cats
Anderson, H.; Davison, S.; Lytle, K. M.; Honkanen, L.; Freyer, J.; Mathlin, J.; Kyöstilä, K.; Inman, L.; Louviere, A.; Chodroff Foran, R.; Forman, O. P.; Lohi, H.; Donner, J.
10.1101/2021.09.06.459083 — genetics — Posted on 2021-09-06
3401 Parallel evolution of phage resistance - virulence trade - offs during in vitro and nasal Pseudomonas aeruginosa phage treatment
Castledine, M.; Padfield, D.; Sierocinski, P.; Soria Pascual, J.; Hughes, A.; Mäkinen, L.; Friman, V.-P.; Pirnay, J.-P.; Merabishvili, M.; De Vos, D.; Buckling, A.
10.1101/2021.09.06.459069 — evolutionary biology — Posted on 2021-09-06
3403 'Lose-to-gain' adaptation to genome decayin the structure of the smallest eukaryotic ribosomes
Nicholson, D.; Salamina, M.; Panek, J.; Helena-Bueno, K.; Brown, C. R.; Hirt, R. P.; Ranson, N. A.; Melnikov, S. V.
10.1101/2021.09.06.458831 — evolutionary biology — Posted on 2021-09-06
3404 Ecological constraints on highly evolvable olfactory receptor genes and morphology
Yohe, L. R.; Fabbri, M.; Lee, D.; Davies, K.; Yohe, T. P.; Sanchez, M. K.; Rengifo, E.; Hall, R.; Mutumi, G.; Hedrick, B. P.; Sadier, A. A.; Simmons, N. B.; Sears, K. E.; Dumont, E.; Rossiter, S.; Bhullar, B.-A.; Davalos, L.
10.1101/2021.09.06.459178 — evolutionary biology — Posted on 2021-09-06
3410 Fibroadipogenic Progenitors contribute to microvascular repair during skeletal muscle regeneration
Ollitrault, D.; Buffa, V.; Correra, R.; Sayed, A.; Hoareau, B.; Pohle-Kronawitter, S.; Stricker, S.; Hulot, J.-S.; Valente, M.; Marazzi, G.; Sassoon, D.
10.1101/2021.09.06.459112 — cell biology — Posted on 2021-09-06
3416 Evidence of structural rearrangements and variability in pESI(like) megaplasmids of S.Infantis by resolving the pESI-like-blaCTX-M-1 positive variant.
Alba, P.; Carfora, V.; Feltrin, F.; Iurescia, M.; Diaconu, E. L.; Cordaro, G.; Dell'Aira, E.; Marani, I.; Giacomi, A.; Franco, A.; Battisti, A.
10.1101/2021.09.06.459061 — microbiology — Posted on 2021-09-06
3417 Distinct inflammatory and transcriptomic profiles in dominant versus subordinate males in mouse social hierarchies
Lee, W.; Milewski, T. M.; Dwortz, M. F.; Young, R. L.; Gaudet, A. D.; Fonken, L. K.; Champagne, F. A.; Curley, J. P.
10.1101/2021.09.04.458987 — immunology — Posted on 2021-09-06
3422 Metformin in nucleus accumbens core reduces cue-induced cocaine seeking in male and female rats
Chan, A.; Willard, A.; Mulloy, S.; Ibrahim, N.; Sciaccotta, A.; Schonfeld, M.; Spencer, S.
10.1101/2021.09.05.458975 — neuroscience — Posted on 2021-09-06
3424 Smoothness discriminates physical from motor imagery practice of arm-reaching movements.
Ruffino, C.; Rannaud Monany, D.; Papaxanthis, C.; Hilt, P. M.; Gaveau, J.; Lebon, F.
10.1101/2021.09.06.459053 — neuroscience — Posted on 2021-09-06
3426 Batch Effects are Causal Effects: Applications in Human Connectomics
Bridgeford, E. W.; Powell, M.; Kiar, G.; Lawrence, R.; Caffo, B.; Milham, M.; Vogelstein, J. T.
10.1101/2021.09.03.458920 — neuroscience — Posted on 2021-09-06
3427 Supervised Phenotype Discovery from Multimodal Brain Imaging
Gong, W.; Bai, S.; Zheng, Y.-Q.; Beckmann, C.; Smith, S. M.
10.1101/2021.09.03.458926 — neuroscience — Posted on 2021-09-06
3428 Global Mapping of Mouse CSF Flow via HEAP-METRIC Phase-contrast MRI
Li, J.; Pei, M.; Bo, B.; Zhao, X.; Cang, J.; Fang, F.; Liang, Z.
10.1101/2021.09.04.459006 — neuroscience — Posted on 2021-09-06
3437 Machine Learning prediction of cardiac resynchronisation therapy response from combination of clinical and model-driven data
Khamzin, S.; Dokuchaev, A.; Bazhutina, A.; Chumarnaya, T.; Zubarev, S.; Lyubimtseva, T.; Lebedeva, V.; Lebedev, D.; Gurev, V.; Solovyova, O.
10.1101/2021.09.03.458464 — physiology — Posted on 2021-09-06
3438 SYS-Mut: Decoding the Functional Significance of Rare Somatic Mutations in Cancer
Khalighi, S.; Joseph, P.; Babu, D.; Singh, S.; LaFramboise, T.; Guda, K.; Varadan, V.
10.1101/2021.09.03.458896 — cancer biology — Posted on 2021-09-06
3439 Reprogramming the neuroblastoma epigenome with a mitochondrial uncoupler
Jiang, H.; Greathouse, R. L.; He, B.; Li, Y.; Li, A. M.; Forgo, B.; Yip, M.; Li, A.; Shih, M.; Banuelos, S.; Zhou, M.; Gruber, J.; Shimada, H.; Chiu, B.; Ye, J.
10.1101/2021.09.05.459035 — cancer biology — Posted on 2021-09-06
3446 Allosteric cooperation in β-lactam binding to a non-classical transpeptidase
Ahmad, N.; Kachhap, S.; Chauhan, V.; Juneja, P.; Sharma, K.; Bullen, C. K.; Borowski, T.; Bishai, W. R.; Lamichhane, G.; Kumar, P.
10.1101/2021.09.06.459080 — biochemistry — Posted on 2021-09-06
3448 Relationship Between Inter-individual Variation in Circadian Rhythm and Sociality: A case Study Using Halictid Bees
Melendez Cartagena, S.; Ortiz-Alvarado, C. A.; Ordonez, P.; Cordero-Martinez, C. S.; Ambrose, A. F.; Roman Lizasoain, L. A.; Santos Vega, M. A.; Velez Velez, A. V.; Acevedo-Gonzalez, J. P.; Gibbs, J.; Petanidou, T.; Tscheulin, T.; Barthell, J. T.; Gonzalez, V. H.; Giray, T.; Agosto-Rivera, J. L.
10.1101/2021.09.03.458748 — animal behavior and cognition — Posted on 2021-09-06
3449 Genome size evolution in the beetle genus Diabrotica
Lata, D.; Coates, B. S.; Walden, K. K. O.; Robertson, H. M.; Miller, N. J.
10.1101/2021.09.04.458993 — genomics — Posted on 2021-09-06
3458 The Immunomodulatory Effects of Social Isolation in Mice are Linked to Temperature Control
Hamilton, A.; Rizzo, R.; Brod, S.; Ono, M.; Perretti, M.; Cooper, D.; D'Acquisto, F.
10.1101/2021.09.03.458884 — immunology — Posted on 2021-09-06
3460 Temporal irreversibility of neural dynamics as a signature of consciousness
de la Fuente, L. A.; Zamberlan, F.; Bocaccio, H.; Kringelbach, M. L.; Deco, G.; Tagliazucchi, E.
10.1101/2021.09.02.458802 — neuroscience — Posted on 2021-09-06
3461 Mosaic and non-mosaic pcdh19 mutation leads to neuronal hyperexcitability in zebrafish
Robens, B. K.; Yang, X.; McGraw, C. M.; Turner, L. H.; Robens, C.; Thyme, S.; Rotenberg, A.; Poduri, A.
10.1101/2021.09.03.458732 — neuroscience — Posted on 2021-09-06
3463 Interrelations between delta waves, spindles and slow oscillations in human NREM sleep and their functional role in memory
Ladenbauer, J.; Wuest, L.; Antonenko, D.; Malinowski, R.; Shevchuk, L.; Grittner, U.; Obermayer, K.; Floeel, A.
10.1101/2021.09.03.458607 — neuroscience — Posted on 2021-09-06
3466 Pilot identification of the Live-1/Prox-1 expressing lymphatic vessels and lymphatic elements in the unaffected and affected human brain
Semyachkina-Glushkovskaya, O. V.; Fedosov, I.; Navolokin, N.; Shirokov, A.; Maslyakova, G.; Bucharskaya, A.; Blokhina, I.; Terskov, A.; Khorovodov, A.; Postnov, D.; Kurths, J.
10.1101/2021.09.05.458990 — neuroscience — Posted on 2021-09-06
3468 CluSem: Accurate Clustering-based Ensemble Methodto Predict Motor Imagery Tasks from Multi-channelEEG Data
Miah, M. O.; Muhammod, R.; Al Mamun, K. A.; Farid, D. M.; Kumar, S.; Sharma, A.; Dehzangi, A.
10.1101/2021.09.05.458710 — neuroscience — Posted on 2021-09-06
3471 ProteinPrompt: a webserver for predictingprotein-protein interactions
Canzler, S.; Ulbricht, D.; Fischer, M.; Ristic, N.; Hildebrand, P. W.; Staritzbichler, R.
10.1101/2021.09.03.458859 — bioinformatics — Posted on 2021-09-06
3473 Emergent intra-pair sex differences and behavioral coordination in pair bonded prairie voles
Brusman, L. E.; Protter, D. S. W.; Fultz, A. C.; Paulson, M. U.; Chapel, G. D.; Elges, I. O.; Cameron, R. T.; Beery, A. K.; Donaldson, Z. R.
10.1101/2021.09.03.458892 — animal behavior and cognition — Posted on 2021-09-06
3475 An ex vivo human bone marrow milieu identifies CDH2 as a driver of niche-mediated treatment resistance in leukaemia
Pal, D.; Blair, H.; Boyd, S.; Angel, S.; Nizami, S.; Isa, A.; Beckett, M.; Nelson, R.; Wilson, A.; Singh, M.; Sankar, S.; Tirtakusuma, R.; Nakjang, S.; Knill, C.; Fuller, A.; McNeill, H.; Russell, L.; Schwab, C.; Zhou, P.; Sinclair, P.; Coxhead, J.; Filby, A.; Allan, J.; Halsey, C.; Harrison, C.; Moorman, A.; Heidenreich, O.; Vormoor, J.
10.1101/2021.06.18.448490 — cancer biology — Posted on 2021-09-06
3476 Redox-dependent Structure and Dynamics of Macrophage Migration Inhibitory Factor Reveal Sites of Latent Allostery
Skeens, E.; Gadzuk-Shea, M. M.; Shah, D.; Bhandari, V.; Schweppe, D. K.; Berlow, R. B.; Lisi, G. P.
10.1101/2021.09.01.458630 — biophysics — Posted on 2021-09-06
3481 MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution
Kaufmann, T. L.; Petkovic, M.; Watkins, T. B.; Colliver, E. C.; Laskina, S.; Thapa, N.; Minussi, D. C.; Navin, N.; Swanton, C.; Van Loo, P.; Haase, K.; Tarabichi, M.; Schwarz, R. F.
10.1101/2021.02.28.433227 — bioinformatics — Posted on 2021-09-06
3483 Modelling the spatiotemporal spread of beneficial alleles using ancient genomes
Muktupavela, R. A.; Petr, M.; Segurel, L.; Korneliussen, T. S.; Novembre, J.; Racimo, F.
10.1101/2021.07.21.453231 — evolutionary biology — Posted on 2021-09-06
3484 Imaging erythrocyte sedimentation in whole blood
Darras, A.; Breunig, H. G.; John, T.; Zhao, R.; Koch, J.; Kummerow, C.; König, C.; Wagner, C.; Kaestner, L.
10.1101/2021.08.31.458375 — biophysics — Posted on 2021-09-06
3485 Shrimp parvovirus circular DNA fragments arise from both endogenous viral elements (EVE) and the infecting virus
Taengchaiyaphum, S.; Buathongkam, P.; Sukthaworn, S.; Wongkhaluang, P.; Sritunyalucksana, K.; Flegel, T. W.
10.1101/2021.06.08.447433 — molecular biology — Posted on 2021-09-06
3486 Lowland plant migrations into alpine ecosystems amplify soil carbon loss under climate warming
Walker, T. W. N.; Gavazov, K.; Guillaume, T.; Lambert, T.; Mariotte, P.; Routh, D.; Signarbieux, C.; Block, S.; Muenkemueller, T.; Nomoto, H.; Crowther, T. W.; Richter, A.; Buttler, A.; Alexander, J. M.
10.1101/2021.07.21.453211 — ecology — Posted on 2021-09-06
3488 Autonomic and respiratory components of orienting behaviors are mediated by descending pathways originating from the superior colliculus
Lynch, E.; Dempsey, B. R.; Saleeba, C.; Monteiro, E.; Turner, A. J.; Burke, P. G.; Allen, A. M.; Dampney, R. A.; Hildreth, C. M.; Cornish, J. L.; Goodchild, A. K.; McMullan, S.
10.1101/2021.06.10.447470 — neuroscience — Posted on 2021-09-06
3494 Enhancer-priming in ageing human bone marrow mesenchymal stromal cells contributes to immune traits
Lai, M. C.; Ruiz-Velasco, M.; Arnold, C.; Sigalova, O.; Bunina, D.; Berest, I.; Ding, X.; Hennrich, M. L.; Poisa-Beiro, L.; Claringbould, A.; Mathioudaki, A.; Pabst, C.; Ho, A. D.; Gavin, A.-C.; Zaugg, J. B.
10.1101/2021.09.03.458728 — systems biology — Posted on 2021-09-05
3495 Integrative multi-omics identifies high risk Multiple Myeloma segment associated with significant DNA loss and dysregulated DNA repair and cell cycle pathways
Ortiz Estevez, M.; Samur, M.; Towfic, F.; Flynt, E.; Stong, N.; Jang, I. S.; Wang, K.; Vyas, P.; Munshi, N.; Avet-Loiseau, H.; Trotter, M. W.; Morgan, G. J.; Walker, B.; Thakurta, A.
10.1101/2021.09.03.458836 — cancer biology — Posted on 2021-09-05
3496 Generation of transducible version of a recombinant human HAND2 transcription factor from Escherichia coli
Haridhasapavalan, K. K.; Sundaravadivelu, P. K.; Mohapatra, A.; Joshi, N.; Das, N. J.; THUMMER, R. P.
10.1101/2021.09.04.458986 — bioengineering — Posted on 2021-09-05
3502 Rapid dynamic naturalistic monitoring of bradykinesia in Parkinson's disease using a wrist-worn accelerometer
Habets, J.; Herff, C.; Kubben, P. L.; Kuijf, M. L.; Temel, Y.; Evers, L. J.; Bloem, B.; Starr, P. A.; Gilron, R.; Little, S. J.
10.1101/2021.09.03.458142 — neuroscience — Posted on 2021-09-05
3503 Collagen VI regulates motor circuit plasticity and motor performance by cannabinoid modulation
Lam, D.; Williams, R. H.; Lujan, E.; Tanabe, K.; Huber, G.; Saw, N. L.; Merl-Pham, J.; Salminen, A. V.; Lohse, D.; Spendiff, S.; Plastini, M.; Zech, M.; Lochmuller, H.; Geerlof, A.; Hauck, S. M.; Shamloo, M.; Wernig, M.; Winkelmann, J.
10.1101/2021.09.03.458830 — neuroscience — Posted on 2021-09-05
3506 Comprehensive cancer-oriented biobanking resource of human samples for studies of post-zygotic genetic variation involved in cancer predisposition
Filipowicz, N.; Horbacz, M.; Drezek, K.; Wojdak, A.; Szymanowski, J.; Rychlicka-Buniowska, E.; Juhas, U.; Duzowska, K.; Nowikiewicz, T.; Stankowska, W.; Chojnowska, K.; Andreou, M.; Lawrynowicz, U.; Wojcik, M.; Davies, H.; Srutek, E.; Bienkowski, M.; Milian-Ciesielska, K.; Zdrenka, M.; Ambicka, A.; Przewoznik, M.; Harazin-Lechowska, A.; Adamczyk, A.; Kowalski, J.; Bala, D.; Wisniewski, D.; Tkaczynski, K.; Kamecki, K.; Drzewiecka, M.; Wronski, P.; Siekiera, J.; Ratnicka, I.; Jankau, J.; Wierzba, K.; Skokowski, J.; Polom, K.; Przydacz, M.; Belch, L.; Chlosta, P.; Matuszewski, M.; Okon, K.; Rostk
10.1101/2021.09.03.458865 — cancer biology — Posted on 2021-09-05
3511 Highly specific chimeric DNA-RNA guided genome editing with enhanced CRISPR-Cas12a system
Kim, H.; Lee, W.-j.; Kim, C. H.; Oh, Y.; Gwon, L. W.; Lee, H.; Song, W.; Hur, J. K.; Lim, K.-S.; Jeong, K. J.; Nam, K.-H.; Won, Y.-S.; Lee, Y.; Kim, Y.-H.; Huh, J.-W.; Jun, B.-H.; Lee, D.-S.; Lee, S. H.
10.1101/2021.09.04.458978 — biochemistry — Posted on 2021-09-05
3512 Free spermidine evokes superoxide radicals that manifest toxicity
Kumar, V.; Mishra, R. K.; Ghose, D.; Kalita, A.; Prakash, A.; Mitra, G.; Arora, A.; Dutta, D.
10.1101/2021.09.04.458997 — biochemistry — Posted on 2021-09-05
3514 The genetics of eating behaviors: research in the age of COVID-19
Hannum, M. E.; Lin, C.; Bell, K. A.; Toskala, A. K.; Koch, R. R.; Galaniha, T.; Nolden, A.; Reed, D. R.; Joseph, P. V.
10.1101/2021.09.03.458854 — genetics — Posted on 2021-09-05
3517 Transcriptome phylogenies support ancient evolutionary transitions in bioluminescence traits of cypridinid ostracods
Ellis, E. A.; Goodheart, J. A.; Hensley, N. M.; Gonzalez, V. L.; Reda, N. J.; Rivers, T. J.; Morin, J. G.; Torres, E.; Gerrish, G. A.; Oakley, T. H.
10.1101/2021.09.03.458903 — evolutionary biology — Posted on 2021-09-05
3518 Unearthing modes of climatic adaptation in underground storage organs across Liliales
Tribble, C. M.; May, M. R.; Jackson-Gain, A.; Zenil-Ferguson, R.; Specht, C. D.; Rothfels, C. J.
10.1101/2021.09.03.458928 — evolutionary biology — Posted on 2021-09-05
3520 Prevalence of mutualism in a simple model of microbial co-evolution
Stucchi, L.; Galeano, J.; Pastor, J. M.; Iriondo, J. M.; Cuesta, J. A.
10.1101/2021.09.03.458878 — ecology — Posted on 2021-09-05
3525 ISL1 is an essential determinant of structural and functional tonotopic representation of sound
Filova, I.; Pysanenko, K.; Tavakoli, M.; Vochyanova, S.; Dvorakova, M.; Bohuslavova, R.; Smolik, O.; Benesova, S.; Valihrach, L.; Yamoah, E. N.; Syka, J.; Fritzsch, B.; Pavlinkova, G.
10.1101/2021.09.03.458707 — neuroscience — Posted on 2021-09-05
3530 Generation of CD34+CD43+ hematopoietic progenitors to induce thymocytes from human pluripotent stem cells
Flippe, L.; Gaignerie, A.; Serazin, C.; Baron, O.; Saulquin, X.; Anegon, I.; David, L.; Guillonneau, C.
10.1101/2021.09.02.458682 — developmental biology — Posted on 2021-09-05
3531 Distinct repertoire development history during affinity maturation of antigen-responding VHH antibody
Matsuda, T.; Akazawa-Ogawa, Y.; Komaba, L.-K.; Kiyose, N.; Miyazaki, N.; Mizuguchi, Y.; Fukuta, T.; Ito, Y.; Hagihara, Y.
10.1101/2021.06.29.449501 — immunology — Posted on 2021-09-05
3532 The timescale and magnitude of 1/f aperiodic activity decreases with cortical depth in humans, macaques and mice
Halgren, M.; Kang, R.; Voytek, B.; Ulbert, I.; Fabo, D.; Eross, L. G.; Wittner, L.; Madsen, J.; Doyle, W. K.; Devinsky, O.; Halgren, E.; Harnett, M. T.; Cash, S. S.
10.1101/2021.07.28.454235 — neuroscience — Posted on 2021-09-05
3533 Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GIT1/mTORC1 assembly
Conde-Dusman, M. J.; Dey, P. N.; Elia-Zudaire, O.; G. Rabaneda, L.; Garcia-Lira, C.; Grand, T.; Briz, V.; Velasco, E. R.; Andero Gali, R.; Ninerola, S.; Barco, A.; Paoletti, P.; Wesseling, J. F.; Gardoni, F.; Tavalin, S. J.; Perez-Otano, I.
10.1101/2021.09.03.458895 — neuroscience — Posted on 2021-09-05
3534 Robust de novo design of protein binding proteins from target structural information alone
Cao, L.; Coventry, B.; Goreshnik, I.; Huang, B.; Park, J. S.; Jude, K. M.; Markovic, I.; Kadam, R. U.; Verschueren, K. H. G.; Verstraete, K.; Walsh, S. T. R.; Bennett, N.; Phal, A.; Yang, A.; Kozodoy, L.; DeWitt, M.; Picton, L.; Miller, L.; Strauch, E.-M.; Halabiya, S.; Hammerson, B.; Yang, W.; Benard, S.; Stewart, L.; Wilson, I. A.; Ruohola-Baker, H.; Schlessinger, J.; Lee, S.; Savvides, S. N.; Garcia, K. C. N.; Baker, D.
10.1101/2021.09.04.459002 — synthetic biology — Posted on 2021-09-05
3536 Genetic, metabolic, and molecular insights into the diverse outcomes of diet-induced obesity in mice
Bachmann, A. M.; Morel, J.-D. H.; El Alam, G.; Rodriguez-Lopez, S.; de lima, T. I.; Goeminne, L. J. E.; Benegiamo, G.; Bou Sleiman, M. S.; Auwerx, J.
10.1101/2021.09.02.458729 — bioinformatics — Posted on 2021-09-05
3537 Structure and ion-release mechanism of PIB-4-type ATPases
Gronberg, C.; Hu, Q.; Mahato, D. R.; Longhin, E.; Salustros, N.; Duelli, A.; Eriksson, J.; Rao, K. U.; Henderson, D. I.; Meloni, G.; Andersson, M.; Croll, T.; Godaly, G.; Wang, K.; Gourdon, P.
10.1101/2021.09.01.458532 — biochemistry — Posted on 2021-09-05
3538 Allosteric mechanism of signal transduction in the two-component system histidine kinase PhoQ
Mensa, B.; Polizzi, N. F.; Molnar, K. S.; Natale, A. M.; Lemmin, T.; DeGrado, W. F.
10.1101/2021.09.03.458835 — biochemistry — Posted on 2021-09-05
3543 Different B cell subpopulations show distinct patterns in their IgH repertoire metrics
Ghraichy, M.; von Niederhäusern, V.; Kovaltsuk, A.; Galson, J. D.; Deane, C. M.; Trück, J.
10.1101/2021.09.01.458522 — immunology — Posted on 2021-09-05
3546 Self-organized morphogenesis of a human neural tube in vitro by geometric constraints
Karzbrun, E.; Khankhel, A.; Megale, H.; Glasauer, S.; Wyle, Y.; Britton, G.; Warmflash, A.; Kosik, K. S.; Siggia, E.; Shraiman, B.; Streichan, S. J.
10.1101/2021.07.24.453659 — developmental biology — Posted on 2021-09-05
3547 Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant
Liu, Y.; Liu, J.; Johnson, B. A.; Xia, H.; Ku, Z.; Schindewolf, C.; Widen, S. G.; An, Z.; Weaver, S.; Menachery, V. D.; Xie, X.; Shi, P.-Y.
10.1101/2021.08.12.456173 — microbiology — Posted on 2021-09-05
3551 Extracellular matrix and spores impart structural hierarchy and compositional heterogeneity in Bacillus subtilis biofilms
Azulay, D. N.; Spaeker, O.; Ghrayeb, M.; Wilsch-Brauninger, M.; Scoppola, E.; Burghammer, M.; Zizak, I.; Bertinetti, L.; Politi, Y.; Chai, L.
10.1101/2021.07.27.453653 — microbiology — Posted on 2021-09-05
3553 Incorporating structural knowledge into unsupervised deep learning for two-photon imaging data
Eichin, F.; Hackenberg, M.; Broichhagen, C.; Kilias, A.; Schmoranzer, J.; Bartos, M.; Binder, H.
10.1101/2021.05.18.443587 — bioinformatics — Posted on 2021-09-05
3557 Variation and process of life history evolution in insular dwarfism as revealed by a natural experiment
Hayashi, S.; Kubo, M. O.; Sanchez-Villagra, M. R.; Taruno, H.; Izawa, M.; Shiroma, T.; Nakano, T.; Fujita, M.
10.1101/2020.12.23.424186 — evolutionary biology — Posted on 2021-09-04
3559 Toward Reliable Network Neuroscience for Mapping Individual Differences
Jiang, C.; Betzel, R.; He, Y.; Wang, Y.-S.; Xing, X.-X.; Zuo, X.-N.
10.1101/2021.05.06.442886 — neuroscience — Posted on 2021-09-04
3561 Metabolic modeling of the International Space Station microbiome reveals key microbial interactions
Kumar, R. K.; Singh, N. K.; Balakrishnan, S.; Parker, C. W.; Raman, K.; Venkateswaran, K.
10.1101/2021.09.03.458819 — systems biology — Posted on 2021-09-04
3562 Native Metabolomics Identifies the Rivulariapeptolide Family of Protease Inhibitors
Reher, R.; Aron, A. T.; Fajtova, P.; Liu, C.; Ben Shalom, I. Y.; Bittremieux, W.; Wang, M.; Matos-Hernandez, M. L.; Alexander, K. L.; Caro-Diaz, E. J.; Naman, C. B.; Dorrestein, P. C.; O'Donoghue, A. J.; Gerwick, W. H.; Petras, D.
10.1101/2021.09.03.458897 — systems biology — Posted on 2021-09-04
3563 BCN057, a Modulator of GSK3b Induces KRAS G12D Mutant Pancreatic Cancer Cell Death
Singer, E. M.; Chugh, R. M.; Bhanja, P.; Gomez, A.; Gao, L.; Whitelegge, J. P.; McBride, W. H.; Saha, S.; Norris, A. J.
10.1101/2021.09.03.458938 — cancer biology — Posted on 2021-09-04
3564 Versatile, do-it-yourself, low-cost spinning disk confocal microscope
Halpern, A. R.; Lee, M. Y.; Howard, M. D.; Woodworth, M. A.; Nicovich, P. R.; Vaughan, J. C.
10.1101/2021.09.04.458950 — biophysics — Posted on 2021-09-04
3566 Plasma derived cell-free mitochondrial DNA originates mainly from circulating cell-free mitochondria
Roch, B.; Pisareva, E.; Sanchez, C.; Pastor, B.; Tanos, R.; Mirandola, A.; Mazard, T.; Al Amir Dache, Z.; Thierry, A.
10.1101/2021.09.03.458846 — genomics — Posted on 2021-09-04
3569 Aberrant localization of CDC42 C-terminal variants to the Golgi apparatus drives pyrin inflammasome-dependent autoinflammation
Nishitani-Isa, M.; Mukai, K.; Honda, Y.; Nihira, H.; Shibata, H.; Tanaka, T.; Kodama, K.; Hiejima, E.; Izawa, K.; Kawasaki, Y.; Osawa, M.; Katata, Y.; Onodera, S.; Watanabe, T.; Kure, S.; Takita, J.; Ohara, O.; Saito, M. K.; Nishikomori, R.; Taguchi, T.; Sasahara, Y.; Yasumi, T.
10.1101/2021.09.03.458902 — immunology — Posted on 2021-09-04
3570 In lupus nephritis, specific in situ inflammatory states are associated with refractory disease and progression to renal failure
Abraham, R.; Durkee, M. S.; Ai, J.; Veselits, M.; Casella, G.; Asano, Y.; Chang, A.; Ko, K.; Oshinsky, C.; Peninger, E.; Giger, M.; Clark, M. R.
10.1101/2021.09.03.458909 — immunology — Posted on 2021-09-04
3571 Functional differentiation in the language network revealed by lesion-symptom mapping
Matchin, W.; Basilakos, A.; den Ouden, D.-B.; Stark, B.; Hickok, G.; Fridriksson, J.
10.1101/2020.07.17.209262 — neuroscience — Posted on 2021-09-04
3574 Numb is required for optimal contraction of skeletal muscle
De Gasperi, R.; Mo, C.; Azulai, D.; Wang, Z.; Harlow, L. M.; Du, Y.; Graham, Z. A.; Liu, X.-h.; Guo, L.; Zhang, B.; Ko, F.; Raczkowski, A. M.; Bauman, W. A.; Zhao, W.; Brotto, M.; Cardozo, C. P.
10.1101/2021.09.03.453960 — physiology — Posted on 2021-09-04
3576 CaV1.3 enhanced store operated calcium promotes resistance to androgen deprivation in prostate cancer
O'Reilly, D.; Downing, T. J.; Kouba, S.; Potier-Cartereau, M.; McKenna, D.; Vandier, C.; Buchanan, P. J.
10.1101/2021.09.03.458558 — cancer biology — Posted on 2021-09-04
3577 Enzyme Aggregation and Fragmentation Induced by Catalysis Relevant Species
Gentile, K.; Bhide, A.; Kauffman, J.; Ghosh, S.; Maiti, S.; Adair, J.; Lee, T.-H.; Sen, A.
10.1101/2021.09.03.458882 — biophysics — Posted on 2021-09-04
3578 Protein Structure Prediction Using a Maximum Likelihood Formulation of a Recurrent Geometric Network
Qi, G.; Tollefson, M. R.; Gogal, R. A.; Smith, R. J. H.; AlQuraishi, M.; Schnieders, M. J.
10.1101/2021.09.03.458873 — biophysics — Posted on 2021-09-04
3582 Evolution and functional dynamics of dehydrins in model Brachypodium grasses
Decena Rodriguez, M. A.; Galvez Rojas, S.; Agostini, F.; Sancho Cohen, R.; Contreras Moreira, B.; Des Marais, D.; Hernandez Molina, P.; Catalan, P.
10.1101/2021.09.03.458816 — genetics — Posted on 2021-09-04
3583 Production of offspring from azoospermic mice with meiotic failure: Precise biparental meiosis within halved oocytes
Ogonuki, N.; Kyogoku, H.; Hino, T.; Osawa, Y.; Fujiwara, Y.; Inoue, K.; Kunieda, T.; Mizuno, S.; Tateno, H.; Sugiyama, F.; Kitajima, T.; Ogura, A.
10.1101/2021.09.03.458818 — developmental biology — Posted on 2021-09-04
3585 When development is constantly but weakly perturbed - Canalization by microRNAs
Lu, G.-A.; Zhao, Y.; Chen, Q.; Lin, P.; Tang, T.; Tang, Z.; Liufu, Z.; Wu, C.-I.
10.1101/2021.09.04.458966 — molecular biology — Posted on 2021-09-04
3588 GLS1 is a Protective Factor Rather than a Molecular Target in ARID1A-Mutated Ovarian Clear Cell Carcinoma
Clemente, V.; Nelson, A.; Erickson, B.; Baker, R.; Rubin, N.; Khalifa, M.; Hoshino, A.; Shetty, M.; Lou, E.; Bazzaro, M.
10.1101/2021.09.03.457161 — cancer biology — Posted on 2021-09-04
3589 Structural anatomy of C1 domain interactions with DAG and other agonists
Katti, S. S.; Krieger, I. V.; Ann, J.; Lee, J.; Sacchettini, J. C.; Igumenova, T. I.
10.1101/2021.09.03.458901 — biophysics — Posted on 2021-09-04
3591 An Extended Coatomer Binding Motif in the SARS-CoV-2 Spike Protein
Dey, D.; Singh, S.; Khan, S.; Martin, M.; Schnicker, N.; Gakhar, L.; Pierce, B.; Hasan, S. S.
10.1101/2021.09.03.458953 — biochemistry — Posted on 2021-09-04
3594 Distinct stress-dependent signatures of cellular and extracellular tRNA-derived small RNAs (tDRs)
Li, G.; Manning, A.; Bagi, A.; Yang, X.; Howard, J.; Chan, P. P.; Sweeney, T.; Li, H.; Laurent, B. D.; Kontaridis, M. I.; Laurent, L. C.; Jensen, K. V. K.; Aranki, S. F.; Muehlschlegel, J. D.; Kitchen, R.; Lowe, T. M.; Das, S.
10.1101/2021.09.03.458085 — cell biology — Posted on 2021-09-04
3595 Network analysis outlines strengths and weaknesses of emerging SARS-CoV-2 Spike variants
Manrique, P. D.; Chakraborty, S.; Nguyen, K.; Mansbach, R.; Korber, B.; Gnanakaran, S.
10.1101/2021.09.03.458946 — molecular biology — Posted on 2021-09-04
3596 Genomic evidence for divergent co-infections of SARS-CoV-2 lineages
Zhou, H.-Y.; Cheng, Y.-X.; Xu, L.; Li, J.-Y.; Tao, C.-Y.; Ji, C.-Y.; Han, N.; Yang, R.; Li, Y.; Wu, A.
10.1101/2021.09.03.458951 — microbiology — Posted on 2021-09-04
3598 Wheat EARLY FLOWERING3 is a dawn-expressed circadian oscillator component that regulates heading date
Wittern, L.; Steed, G.; Taylor, L. J.; Greenland, A.; Gardner, K.; Hannah, M. A.; Webb, A. A. R.
10.1101/2021.09.03.458922 — plant biology — Posted on 2021-09-04
3599 A cell atlas of the fly kidney
Xu, J.; Liu, Y.; Li, H.; Tarashansky, A. J.; Kalicki, C. H.; Hung, R.-J.; Hu, Y.; Comjean, A.; Kolluru, S. S.; Wang, B.; Quake, S. R.; Luo, L.; McMahon, A. P.; Dow, J. A. T.; Perrimon, N.
10.1101/2021.09.03.458871 — developmental biology — Posted on 2021-09-04
3603 Recruitment of an ancient branching program to suppress carpel development in maize flowers
Klein, H.; Gallagher, J. P.; Demesa-Arevalo, E.; Abraham-Juarez, M. J.; Heeney, M.; Feil, R.; Lunn, J. E.; Xiao, Y.; Chuck, G. S.; Whipple, C. J.; Jackson, D.; Bartlett, M. E.
10.1101/2021.09.03.458935 — plant biology — Posted on 2021-09-04
3605 6',6'-Difluoro-aristeromycin is a potent inhibitor of MERS-coronavirus replication
S. Ogando, N. S.; Zevenhoven-Dobbe, J.; Jarhad, D.; Tripathi, S. K.; Lee, H. W.; Jeong, L. S.; Snijder, E. J.; Posthuma, C. C.
10.1101/2021.05.20.445077 — microbiology — Posted on 2021-09-04
3607 A vacuolar hexose transport is required for xylem development in the inflorescence stem of Arabidopsis.
Aubry, E.; Hoffmann, B.; Vilaine, F.; Gilard, F.; Klemens, P. A. W.; Guerard, F.; Gakiere, B.; Neuhaus, H. E.; Bellini, C.; Dinant, S.; Le Hir, R.
10.1101/2020.12.09.417345 — plant biology — Posted on 2021-09-04
3608 Global anti-tumor immunity after localized, bioengineered Treg depletion
Majedi, F. S.; Hasani-Sadrabadi, M. M.; Thauland, T. J.; Keswani, S. G.; Li, S.; Bouchard, L.-S.; Butte, M. J.
10.1101/2021.09.02.458797 — immunology — Posted on 2021-09-04
3609 Hybrid ssDNA repair templates enable high yield genome engineering in primary cells for disease modeling and cell therapy manufacturing
Shy, B. R.; Vykunta, V.; Ha, A.; Roth, T. L.; Talbot, A.; Nguyen, D. N.; Chen, Y. Y.; Blaeschke, F.; Vedova, S.; Mamedov, M.; Chung, J.-Y.; Li, H.; Wolf, J.; Martin, T. G.; Ye, L.; Eyquem, J.; Esensten, J.; Marson, A.
10.1101/2021.09.02.458799 — synthetic biology — Posted on 2021-09-04
3611 Reovirus sensitizes microsatellite stable colorectal cancer to anti-PD-1 treatment via cross-talk in innate and adaptive immune systems
Augustine, T.; John, P.; Friedman, T.; Jiffry, J.; Guzik, H.; Mannan, R.; Gupta, R.; Delano, C.; Mariadason, J.; Zang, X.; Maitra, R.; Goel, S.
10.1101/2021.09.03.458915 — cancer biology — Posted on 2021-09-04
3613 Highly Efficient Knockin in Human iPS Cells and Rat Embryos by CRISPR/Cas9 Molecular Optimization
Chenouard, V.; Leray, I.; Tesson, L.; Remy, S.; Fortun, A.; Bernardeau, K.; Cherifi, Y.; David, L.; Anegon, I.
10.1101/2021.09.03.458921 — bioengineering — Posted on 2021-09-04
3614 Quantitative accuracy and precision in multiplexed single-cell proteomics.
Ctortecka, C.; Stejskal, K.; Krssakova, G.; Mendjan, S.; Mechtler, K.
10.1101/2021.09.03.458853 — biochemistry — Posted on 2021-09-04
3619 Complex genetic patterns and distribution limits mediated by native congeners of the worldwide invasive red-eared slider turtle
Espindola, S.; Vazquez-Dominguez, E.; Nakamura, M.; Osorio-Olvera, L.; Martinez-Meyer, E.; Myers, E. A.; Overcast, I.; Reid, B. N.; Burbrink, F.
10.1101/2021.09.02.458785 — evolutionary biology — Posted on 2021-09-04
3620 Using hypertemporal Sentinel-1 data to predict forest growing stock volume
Ge, S.; Tomppo, E.; Rauste, Y.; McRoberts, R. E.; Praks, J.; Gu, H.; Su, W.; Antropov, O.
10.1101/2021.09.02.458789 — ecology — Posted on 2021-09-04
3622 FOXO1 represses Sprouty2 and Sprouty4 expressionin endothelial cells to promote arterial specification and vascular remodeling in the mouse yolk sac
Li-Villarreal, N.; Wong, R. L. Y.; Garcia, M. D.; Udan, R. S.; Poche, R. A.; Rasmussen, T. L.; Rhyner, A. M.; Wythe, J. D.; Dickinson, M. E.
10.1101/2021.09.02.458792 — developmental biology — Posted on 2021-09-04
3623 The human disease gene CLEC16A encodes an intrinsically disordered protein region required for mitochondrial quality control
Gingerich, M. A.; Liu, X.; Chai, B.; Pearson, G. L.; Vincent, M. P.; Stromer, T.; Zhu, J.; Sidarala, V.; Renberg, A.; Sahu, D.; Klionsky, D. J.; Schnell, S.; Soleimanpour, S. A.
10.1101/2021.09.03.458272 — molecular biology — Posted on 2021-09-04
3624 Tight association between microbial eukaryote and Imitervirales communities in the Pacific Arctic Ocean
Xia, J.; Kameyama, S.; Prodinger, F.; Yoshida, T.; Cho, K.-H.; Jung, J.; Kang, S.-H.; Yang, E.-J.; Ogata, H.; Endo, H.
10.1101/2021.09.02.458798 — molecular biology — Posted on 2021-09-04
3634 The m6A reader YTHDC2 is essential for escape from KSHV SOX-induced RNA decay
Macveigh-Fierro, D.; Cicerchia, A.; Cadorette, A.; Sharma, V.; Muller, M.
10.1101/2021.09.03.458900 — microbiology — Posted on 2021-09-04
3636 A novel widespread bacterial structure related to the flagellar type III secretion system
Kaplan, M.; Oikonomou, C. M.; Wood, c. R.; Chreifi, G.; Ghosal, D.; Dobro, M.; Yao, Q.; McDowall, A.; Briegel, A.; Beeby, M.; Chang, Y.-W.; Shaffer, C.; Jensen, G. J.
10.1101/2021.09.03.458937 — microbiology — Posted on 2021-09-04
3637 Multifaceted N-degron recognition and ubiquitylation by GID/CTLH E3 ligases
Chrustowicz, J.; Sherpa, D.; Teyra, J.; Loke, M. S.; Popowicz, G.; Basquin, J.; Sattler, M.; Prabu, J. R.; Sidhu, S. S.; Schulman, B. A.
10.1101/2021.09.03.458554 — biochemistry — Posted on 2021-09-04
3640 Recombination and selection against introgressed DNA
Veller, C.; Edelman, N. B.; Muralidhar, P.; Nowak, M. A.
10.1101/846147 — evolutionary biology — Posted on 2021-09-04
3643 Systems analysis shows a role of cytophilic antibodies in shaping innate tolerance to malaria
Lautenbach, M. J.; Yman, V.; Kadri, N.; Plaza, D.; Angenendt, S.; Sonden, K.; Farnert, A.; Sundling, C.
10.1101/2021.09.02.458668 — immunology — Posted on 2021-09-04
3645 Dopamine-dependent cAMP dynamics in basal amygdala glutamatergic neurons
Lutas, A.; Fernando, K.; Zhang, S. X.; Sambangi, A.; Andermann, M. L.
10.1101/2021.09.03.458910 — neuroscience — Posted on 2021-09-04
3648 The OPAQUE1/DISCORDIA2 myosin XI is required for phragmoplast guidance during asymmetric cell division in maize
Nan, Q.; Liang, H.; Mendoza, J.; Liu, L.; Fulzele, A.; Wright, A. J.; Bennett, E. J.; Rasmussen, C.; Facette, M. R.
10.1101/2021.08.29.458084 — plant biology — Posted on 2021-09-04
3650 Redox-dependent Structure and Dynamics of Macrophage Migration Inhibitory Factor Reveal Sites of Latent Allostery
Skeens, E.; Gadzuk-Shea, M. M.; Shah, D.; Bhandari, V.; Schweppe, D. K.; Berlow, R. B.; Lisi, G. P.
10.1101/2021.09.01.458630 — biophysics — Posted on 2021-09-04
3651 Cancer phylogenetic tree inference at scale from 1000s of single cell genomes
Salehi, S.; Dorri, F.; Chern, K.; Kabeer, F.; Rusk, N.; Funnell, T.; Williams, M. J.; Lai, D.; Andronescu, M.; Campbell, K. R.; McPherson, A.; Aparicio, S.; Roth, A.; Shah, S. P.; Bouchard-Cote, A.
10.1101/2020.05.06.058180 — bioinformatics — Posted on 2021-09-04
3653 Canopy spectral reflectance detects oak wilt at the landscape scale using phylogenetic discrimination
Sapes, G.; Lapadat, C.; Schweiger, A. K.; Juzwik, J.; Montgomery, R.; Gholizadeh, H.; Townsend, P. A.; Gamon, J.; Cavender-Bares, J.
10.1101/2021.01.17.427016 — ecology — Posted on 2021-09-03
3655 Multiparametric profiling of cellular lipid metabolism in hypercholesterolemia
Pfisterer, S. G.; Brock, I.; Kanerva, K.; Hlushchenko, I.; Paavolainen, L.; Ripatti, P.; Islam, M. M.; Kyttala, A.; Di Taranto, M. D.; di Frega, A. S.; Fortunato, G.; Kuusisto, J.; Horvath, P.; Ripatti, S.; Laakso, M.; Ikonen, E.
10.1101/2021.04.19.440471 — cell biology — Posted on 2021-09-04
3657 Nascent alt-protein chemoproteomics reveals a repressor of ribosome biogenesis
cao, x.; Harold, C. M.; Bryant, C. J.; Zheng, S.-J.; Khitun, A.; Baserga, S. J.; Slavoff, S. A.
10.1101/2021.06.29.450363 — molecular biology — Posted on 2021-09-03
3660 The neural architecture of language: Integrative modeling converges on predictive processing
Schrimpf, M.; Blank, I. A.; Tuckute, G.; Kauf, C.; Hosseini, E. A.; KANWISHER, N. G.; Tenenbaum, J. B.; Fedorenko, E.
10.1101/2020.06.26.174482 — neuroscience — Posted on 2021-09-03
3661 Rapid fluctuations in functional connectivity of cortical networks encode spontaneous behavior
Benisty, H.; Moberly, A. H.; Lohani, S.; Barson, D.; Coifman, R. R.; Mishne, G.; Cardin, J. A.; Higley, M. J.
10.1101/2021.08.15.456390 — neuroscience — Posted on 2021-09-03
3664 17q21.31 sub-haplotypes underlying H1-associated risk for Parkinsons disease are associated with LRRC37A/2 expression in astrocytes
Bowles, K. R.; Pugh, D. A.; Liu, Y.; Renton, A. E.; Bandres-Ciga, S.; Gan-Or, Z.; Heutink, P.; Siitonen, A.; Bertelsen, S.; Karch, C.; Frucht, S.; Kopell, B. H.; Peter, I.; Park, Y. J.; Hoglinger, G. U.; IPDGC, ; Charney, A. W.; Raj, T.; Crary, J. F.; Goate, A. M.
10.1101/860668 — neuroscience — Posted on 2021-09-04
3671 homeRNA: A self-sampling kit for the collection of peripheral blood and stabilization of RNA
Haack, A. J.; Lim, F. Y.; Kennedy, D. S.; Day, J. H.; Adams, K. N.; Lee, J. J.; Berthier, E.; Theberge, A. B.
10.1101/2021.02.08.430337 — bioengineering — Posted on 2021-09-03
3672 Predictive Maps in Rats and Humans for Spatial Navigation
de Cothi, W.; Nyberg, N.; Griesbauer, E.-M.; Ghaname, C.; Zisch, F.; Fletcher, L.; Newton, C.; Renaudineau, S.; Bendor, D.; Grieves, R.; Duvelle, E.; Barry, C.; Spiers, H. J.
10.1101/2020.09.26.314815 — animal behavior and cognition — Posted on 2021-09-03
3678 Single-cell transcriptome analysis reveals mesenchymal stem cells in cavernous hemangioma
Ji, F.; Liu, Y.; Shi, J.; Liu, C.; Fu, S.; Wang, H.; Ren, B.; Mi, D.; Gao, S.; Sun, D.
10.1101/2021.09.02.458742 — cancer biology — Posted on 2021-09-03
3679 Consequences of coupled barriers to gene flow for the build-up of genomic differentiation
Kunerth, H. D.; Bogdanowicz, S. M.; Searle, J. B.; Harrison, R. G.; Coates, B. S.; Kozak, G. M.; Dopman, E. B.
10.1101/2021.09.02.458401 — evolutionary biology — Posted on 2021-09-03
3680 Implications of sample treatment on characterization of the riverine environmental metabolome
Nelson, A. R.; Toyoda, J.; Chu, R. K.; Tolic, N.; Garayburu-Caruso, V.; Saup, C. M.; Renteria, L.; Wells, J. R.; Stegen, J.; Wilkins, M. J.; Danczak, R. E.
10.1101/2021.09.02.458736 — ecology — Posted on 2021-09-03
3682 Optimization of single dose VSV-based COVID-19 vaccination in hamsters
O'Donnell, K. L.; Clancy, C. S.; Griffin, A. J.; Shifflett, K.; Gourdine, T.; Thomas, T.; Long, C. M.; Furuyama, W.; Marzi, A.
10.1101/2021.09.03.458735 — microbiology — Posted on 2021-09-03
3685 Macrophages in the uterus are functionally specialised and continually replenished from the circulation
Scott, N. A.; Mohiyiddeen, L.; Mariano, L. L.; Ruane, P. T.; Aplin, J. D.; Moran, O. C.; Brison, D. R.; Ingersoll, M. A.; Mann, E. R.
10.1101/2021.09.02.458731 — immunology — Posted on 2021-09-03
3686 Activation of the Zinc-sensing receptor GPR39 promotes T cell reconstitution after hematopoietic stem cell transplant
Iovino, L.; Cooper, K.; deRoos, P.; Kinsella, S.; Evandy, C.; Ugrai, T.; Mazziotta, F.; Ensbey, K. S.; Granadier, D.; Hopwo, K.; Smith, C.; Gagnon, A.; Galimberti, S.; Petrini, M.; Hill, G. R.; Dudakov, J. A.
10.1101/2021.09.02.458741 — immunology — Posted on 2021-09-03
3689 Human spindle variability
Gonzalez, C. E.; Jiang, X.; Gonzalez-Martinez, J.; Halgren, E.
10.1101/2021.09.02.458632 — neuroscience — Posted on 2021-09-03
3691 Integrated Omics Analysis Reveals Sirtuin Signaling is Central to Hepatic Response to a High Fructose Diet
Cox, L. A.; Chan, J.; Rao, P.; Hamid, Z. A.; Glenn, J.; Jadhav, A.; Das, V.; Karere, G.; Quillen, E.; Kavanagh, K.; Olivier, M.
10.1101/2021.09.02.458361 — systems biology — Posted on 2021-09-03
3692 Discovery of highly potent pancoronavirus fusion inhibitors that also effectively inhibit COVID-19 variants from the UK and South Africa
Curreli, F.; Ahmed, S.; Victor, S. M. B.; Drelich, A.; Panda, S. S.; Altieri, A.; Kurkin, A.; Tseng, C.-T.; Hillyer, C.; Debnath, A.
10.1101/2021.09.03.458877 — pharmacology and toxicology — Posted on 2021-09-03
3703 Wildlife in Cameroon harbor diverse coronaviruses including many isolates closely related to human coronavirus 229E
Ntumvi, N. F.; Ngum Ndze, V.; Gillis, A.; Le Doux Diffo, J.; Tamoufe, U.; Takuo, J.-M.; Mouiche, M. M. M.; Nwobegahay, J.; LeBreton, M.; Rimoin, A. W.; Schneider, B. S.; Monagin, C.; McIver, D. J.; Roy, S.; Ayukekbong, J. A.; Saylors, K.; Joly, D. O.; Wolfe, N. D.; Rubin, E. M.; Lange, C. E.
10.1101/2021.09.03.458874 — microbiology — Posted on 2021-09-03
3704 SARS-CoV-2 infection activates dendritic cells via cytosolic receptors rather than extracellular TLRs
van der Donk, L. E. H.; Eder, J.; van Hamme, J. L.; Brouwer, P. J. M.; Brinkkemper, M.; van Nuenen, A. C.; van Gils, M. J.; Sanders, R. W.; Kootstra, N. A.; Bermejo-Jambrina, M.; Geijtenbeek, T. B. H.
10.1101/2021.09.02.458667 — immunology — Posted on 2021-09-03
3709 Anti-prothrombin autoantibodies enriched after infection with SARS-CoV-2 and influenced by strength of antibody response against SARS-CoV-2 proteins
Emmenegger, M.; Kumar, S. S.; Emmenegger, V.; Malinauskas, T.; Buettner, T.; Rose, L.; Schierack, P.; Sprinzl, M. F.; Sommer, C. J.; Lackner, K. J.; Aguzzi, A.; Roggenbuck, D.; Frauenknecht, K. B. M.
10.1101/2021.06.21.449211 — immunology — Posted on 2021-09-03
3710 A bacterial extracellular vesicle-based intranasal vaccine against SARS-CoV-2 protects against disease and elicits neutralizing antibodies to wild-type virus and Delta variant
Jiang, L.; Driedonks, T.; Lowman, M.; Jong, W. S.; van den Berg van Saparoea, H. B.; Dhakal, S.; Zhou, R.; Caputo, C.; Littlefield, K.; Sitaris, I.; Chen, M. W.; Lima, G.; Gololobova, O.; Smith, B.; Mahairaki, V.; Lane, A. P.; Klein, S. L.; Pekosz, A.; Brayton, C. F.; Luirink, J.; Villano, J. S.; Witwer, K. W.
10.1101/2021.06.28.450181 — immunology — Posted on 2021-09-03
3711 Pubertal sex hormones control transcriptional trajectories in the medial preoptic area
Hashikawa, K.; Hashikawa, Y.; Liu, Y.; Rossi, M.; Basiri, M.; Chen, J.; Ahmad, O.; Mukundan, R.; Johnston, N.; McHenry, J.; Palmiter, R.; Rubinow, D.; Zweifel, L.; Stuber, G.
10.1101/2021.09.02.458782 — neuroscience — Posted on 2021-09-03
3713 A comparison of Remdesivir versus Au22Glutathione18 in COVID-19 golden hamsters: a better therapeutic outcome of gold compound
Gao, X.; Gong, Y.; Tan, W.; Jiang, H.; Qi, J.; Zhao, J.; Sun, B.; Gao, X.; Gao, X.; Cao, P.; He, B.; Fan, J.; Dong, Y.; Gao, F.; Yuan, Q.; Zhao, W.; Zhang, C.; Du, Z.; Ye, F.; He, Z.
10.1101/2020.10.16.342097 — pharmacology and toxicology — Posted on 2021-09-03
3715 Extensive germline-somatic interplay drives prostate cancer through HNF1B co-option of TMPRSS2-ERG
Giannareas, N.; Zhang, Q.; Yang, X.; Tian, Y.; Zhang, P.; Yang, Y.; Manninen, A.; Wang, L.; Wei, G.-H.
10.1101/2021.09.02.458755 — cancer biology — Posted on 2021-09-03
3720 Genetic and genomic architecture in eight strains of the laboratory opossum Monodelphis domestica
Xiong, X.; Samollow, P. B.; Cao, W.; Metz, R.; Zhang, C.; Leandro, A. C.; VandeBerg, J. L.; Wang, X.
10.1101/2021.09.02.458745 — genomics — Posted on 2021-09-03
3721 Ether Lipid Biosynthesis Promotes Lifespan Extension and Enables Diverse Prolongevity Paradigms
Cedillo, L.; Li, S.; Ahsan, F.; Emans, S.; Adedoja, A.; Dao, K.; Li, Z.; Peterson, N.; Watrous, J.; Jain, M.; Das, S.; Pukkila-Worley, R.; Soukas, A. A.
10.1101/2021.09.02.457410 — genetics — Posted on 2021-09-03
3722 Genomic signatures of sexual selection on pollen-expressed genes in Arabis alpina
Gutierrez-Valencia, J.; Fracassetti, M.; Horvath, R.; Laenen, B.; Desamore, A.; Drouzas, A. D.; Friberg, M.; Kolar, F.; Slotte, T.
10.1101/2021.09.02.457912 — evolutionary biology — Posted on 2021-09-03
3723 Freshwater dissolved oxygen dynamics: changes due to glyphosate, 2,4-D and their mixture, both under clear and turbid-organic conditions.
Lozano, V. L.; Miranda, C. E.; Alicia, V. L.; Sabio y Garcia, C. A.; Vera, M. S.; Gonzalez, C.; Wolansky, M. J.; Pizarro, H. N.
10.1101/2021.09.02.458549 — ecology — Posted on 2021-09-03
3726 The role of V3 neurons in speed-dependent interlimb coordination during locomotion in mice
Zhang, H.; Shevtsova, N. A.; Deska-Gauthier, D.; Mackay, C.; Dougherty, K. J.; Danner, S. M.; Zhang, Y.; Rybak, I. A.
10.1101/2021.09.01.458603 — neuroscience — Posted on 2021-09-03
3728 Sigma Oscillations Protect or Reinstate Motor Memory Depending on their Temporal Coordination with Slow Waves
Nicolas, J.; King, B. R.; Levesque, D.; Lazzouni, L.; Coffey, E. B.; Swinnen, S.; Doyon, J.; Carrier, J.; Albouy, G.
10.1101/2021.09.02.458683 — neuroscience — Posted on 2021-09-03
3730 Three-dimensional Super-resolved Imaging of Paraffin-embedded Kidney Samples
Unnersjoe-Jess, D.; Ramdedovic, A.; Hoehne, M.; Butt, L.; Koehler, F. C.; Mueller, R.-U.; Hoyer, P. F.; Blom, H.; Schermer, B.; Benzing, T.
10.1101/2021.09.02.458679 — pathology — Posted on 2021-09-03
3732 Alignment of multiple metabolomics LC-MS datasets from disparate diseases to reveal fever-associated metabolites
Nastase, A.-M.; Barrett, M. P.; Cardenas, W. B.; Bertuccez Cordeiro, F.; Zambrano, M.; Andrade, J.; Chang, J.; Regato, M.; Carrillo, E.; Botana, L.; Moreno, J.; Milne, K.; Spence, P. J.; Rowe, J. A.; Rogers, S.
10.1101/2021.09.02.458540 — bioinformatics — Posted on 2021-09-03
3733 Identification of Arhgef12 and Prkci as Genetic Modifiers of Retinal Dysplasia in the Crb1rd8 Mouse Model
Weatherly, S. M.; Collin, G. B.; Charette, J. R.; Stone, L.; Damkham, N.; Hyde, L. F.; Peterson, J. G.; Hicks, W.; Carter, G. W.; Naggert, J. K.; Krebs, M. P.; Nishina, P. M.
10.1101/2021.09.02.458662 — genetics — Posted on 2021-09-03
3735 A climate-based model for tick life cycle: an infinite system of differential equation approach
Chenaoui, C.; Ben Miled, S.; Ndongo, M. S.; Ndiaye, P. I.; Rekik, M.; Darghouth, M. A.
10.1101/2021.09.02.458669 — ecology — Posted on 2021-09-03
3736 Bringing TrackMate in the era of machine-learning and deep-learning.
Ershov, D.; Phan, M.-S.; Pylvänäinen, J. W.; Rigaud, S. U.; Le Blanc, L.; Charles-Orszag, A.; Conway, J. R. W.; Laine, R. F.; Roy, N. H.; Bonazzi, D.; Dumenil, G.; Jacquemet, G.; Tinevez, J.-Y.
10.1101/2021.09.03.458852 — bioinformatics — Posted on 2021-09-03
3737 Kronos scRT: a uniform framework for single-cell replication timing analysis
Gnan, S.; Josephides, J. M.; Wu, X.; Spagnuolo, M.; Saulebekova, D.; Bohec, M.; Dumont, M.; Baudrin, L.; Fachinetti, D.; Baulande, S.; Chen, C.-L.
10.1101/2021.09.01.458599 — genomics — Posted on 2021-09-03
3739 How much the response of rice genotypes to water deficit at the reproductive phase is dependent from environmental conditions?
Pereira de Castro, I.; Lafarge, T.; Pereira de Castro, A.; Roques, S.; Soutiras, A.; Clement-Vidal, A.; Barbosa Filho Botelho, F.; de Raissac, M.
10.1101/2021.09.01.458547 — plant biology — Posted on 2021-09-03
3740 Developmental integration cannot explain major features of stomatal anatomical evolution in seed plants
Muir, C. D.; Conesa, M. A.; Galmes, J.; Pathare, V. S.; Rivera, P.; Rodriguez, R. L.; Terrazas, T.; Xiong, D.
10.1101/2021.09.02.457988 — plant biology — Posted on 2021-09-03
3743 A high resolution single molecule sequencing-based Arabidopsis transcriptome using novel methods of Iso-seq analysis
Zhang, R.; Kuo, R.; Coulter, M.; Calixto, C. P. G.; Entizne, J. C.; Guo, W.; Marquez, Y.; Milne, L.; Riegler, S.; Matsui, A.; Tanaka, M.; Harvey, S.; Yubang, G.; Wiebner-Kroh, T.; Crespi, M.; Denby, K.; Hur, A. b.; Huq, E.; Jantsch, M. F.; Jarmolowski, A.; Koester, T.; Laubinger, S.; Li, Q. Q.; Gu, L.; Seki, M.; Staiger, D.; Sunkar, R.; Szweykowska-Kulinska, Z.; Tu, S.-L.; Wachter, A.; Waugh, R.; Xiong, L.; Zhang, X.-N.; Reddy, A. S. N.; Barta, A.; Kalyna, M.; Brown, J. W.
10.1101/2021.09.02.458763 — plant biology — Posted on 2021-09-03
3745 H3K4me1-marked Enhancer Activation in Resistant Prostate Cancers Implicates SOX4 and MENIN Inhibition as Therapeutic Strategies
Terranova, C.; Maitituoheti, M.; Raman, A. T.; Tang, M.; Anvar, N. E.; Ghosh, A. K.; Amin, S. B.; Schulz, J.; Orouji, E.; Giancotti, F.; Troncoso, P.; Logothetis, C. J.; Thompson, T.; Rai, K.
10.1101/2021.09.02.458625 — cancer biology — Posted on 2021-09-03
3753 Wide-Angle, Monocular Head Tracking using Passive Markers
Vagvolgyi, B. P.; Jayakumar, R. P.; Madhav, M. S.; Knierim, J. J.; Cowan, N.
10.1101/2021.09.01.458583 — neuroscience — Posted on 2021-09-03
3755 A scalable, clinically severe pig model for Duchenne muscular dystrophy
Stirm, M.; Fonteyne, L. M.; Shashikadze, B.; Lindner, M.; Chirivi, M.; Lange, A.; Kaufhold, C.; Mayer, C.; Medugorac, I.; Kessler, B.; Kurome, M.; Zakhartchenko, V.; Hinrichs, A.; Kemter, E.; Krause, S.; Wanke, R.; Arnold, G. J.; Wess, G.; Nagashima, H.; Hrabe de Angelis, M.; Flenkenthaler, F.; Kobelke, L. A.; Bearzi, C.; Rizzi, R.; Baehr, A.; Matiasek, K.; Walter, M. C.; Kupatt, C.; Ziegler, S.; Bartenstein, P.; Froehlich, T.; Klymiuk, N.; Blutke, A.; Wolf, E.
10.1101/2021.09.01.457562 — pathology — Posted on 2021-09-03
3757 FGFR3 activating mutations induce luminal-like papillary bladder tumor formation and favor a male gender bias.
Shi, M.; Moreno-Vega, A.; Fontugne, J.; Meng, X.-Y.; Dufour, F.; Kamoun, A.; Lindskrog, S. V.; Rapinat, A.; Dunois-Larde, C.; Lapage, M.-L.; Chapeaublanc, E.; Levrel, O.; Lebret, T.; Almeida, A.; De Reynies, A.; Dyrskjot, L.; Allory, Y.; Radvanyi, F.; BERNARD-PIERROT, I.
10.1101/2021.09.02.458778 — cancer biology — Posted on 2021-09-03
3759 Multiplexed triage of candidate biomarkers in plasma using internal standard triggered-parallel reaction monitoring mass spectrometry
Kennedy, J. J.; Whiteaker, J. R.; Ivey, R. G.; Burian, A.; Chowdhury, S.; Tsai, C.-F.; Liu, T.; Lin, C.; Murillo, O.; Lundeen, R. A.; Jones, L. A.; Gafken, P. R.; Longton, G.; Rodland, K. D.; Skates, S.; Landua, J.; Wang, P.; Lewis, M. T.; Paulovich, A. G.
10.1101/2021.09.02.458791 — cancer biology — Posted on 2021-09-03
3762 Engineering a thixotropic and biochemically tunable hyaluronan and collagen bioink for biofabrication of multiple tissue construct types
Aleman, J.; Sivakumar, H.; DePalma, T.; Zhou, Y.; Mazzocchi, A.; Huntwork, R. C.; Yoo, K. M.; Banks, S.; Clark, C.; Maycock, A.; Leaks, K.; Enck, K.; Opara, E.; Gatenholm, P.; Welker, M.; Soker, S.; Herberg, S.; Criswell, T.; Skardal, A.
10.1101/2021.09.01.458584 — bioengineering — Posted on 2021-09-03
3767 The Chromatin Remodeling Protein CHD-1 and the EFL-1/DPL-1 Transcription Factor Cooperatively Down Regulate CDK-2 to Control SAS-6 Levels and Centriole Number
Iyer, J.; Gentry, L.; Bergwell, M.; Smith, A.; Guagliardo, S.; Kropp, P. A.; Sankaralingam, P.; Liu, Y.; Spooner, E.; Bowerman, B.; O'Connell, K. F.
10.1101/2021.09.02.458660 — cell biology — Posted on 2021-09-03
3768 Single cell RNA Sequencing Identifies G-protein Coupled Receptor 87 as a Novel Basal Cell Marker of Distal Honeycomb Cysts in Idiopathic Pulmonary Fibrosis
Heinzelmann, K.; Hu, Q.; Hu, Y.; Dobrinskikh, E.; Ulke, H. M.; Ansari, M.; Leavitt, C.; Mirita, C.; Trudeau, T.; Saal, M. L.; Rice, P.; Gao, B.; Janssen, W. J.; Yang, I. V.; Schiller, H. B.; Vladar, E. K.; Lehmann, M.; Königshoff, M.
10.1101/2021.09.03.458324 — cell biology — Posted on 2021-09-03
3769 The serine/threonine kinase MINK1 directly regulates the function of promigratory proteins
Daulat, A.; Wagner, M. S.; Audebert, S.; Kowalczewska, M.; Ariey-Bonnet, J.; Finetti, P.; Bertucci, F.; Camoin, L.; Borg, J.-P.
10.1101/2021.09.02.458712 — cell biology — Posted on 2021-09-03
3773 Sleep spindles track cortical learning patterns for memory consolidation
Petzka, M.; Chatburn, A.; Charest, I.; Balanos, G. M.; Staresina, B. P.
10.1101/2021.09.01.458569 — neuroscience — Posted on 2021-09-03
3776 Targeting the translational machinery in gastrointestinal stromal tumors (GIST) - a new therapeutic vulnerability
Lee, D. M.; Sun, A.; Patil, S. S.; Liu, L.; Rao, A. V.; Trent, P. T.; Amir, A. A.; Liu, C.; Rausch, J. L.; Presutti, L. D.; Amankulor, N.; Shuda, M.; Duensing, A.
10.1101/2021.09.01.458633 — cancer biology — Posted on 2021-09-03
3777 A Generalizable Speech Emotion Recognition Model Reveals Depression and Remission
Hansen, L.; Zhang, Y.-P.; Wolf, D.; Sechidis, K.; Ladegaard, N.; Fusaroli, R.
10.1101/2021.09.01.458536 — bioinformatics — Posted on 2021-09-03
3779 Genetic coupling of life-history and aerobic performance in Atlantic salmon indicates potential constrains on life-history evolution
Prokkola, J. M.; Asheim, E. R.; Morozov, S.; Bangura, P.; Erkinaro, J.; Ruokolainen, A.; Primmer, C. R.; Aykanat, T.
10.1101/2021.08.23.457324 — evolutionary biology — Posted on 2021-09-03
3783 Defective Desmosomal Adhesion Causes Arrhythmogenic Cardiomyopathy by involving an Integrin-αVβ6/TGF-β Signaling Cascade
Schinner, C.; Franz, H.; Zimmermann, A.; Wanuske, M.-T.; Geier, F.; Pelczar, P.; Lorenz, V.; Xu, L.; Stuedle, C.; Maly, P. I.; Kauferstein, S.; Beckmann, B. M.; Kuster, G. M.; Spindler, V.
10.1101/2021.09.02.458734 — cell biology — Posted on 2021-09-03
3785 Optical and computational dissection of emergent prefrontal rewiring to encode fear memory
Agetsuma, M.; Sato, I.; Tanaka, Y. R.; Carrillo-Reid, L.; Kasai, A.; Arai, Y.; Yoshitomo, M.; Inagaki, T.; Hashimoto, H.; Nabekura, J.; Nagai, T.
10.1101/2021.08.31.458461 — neuroscience — Posted on 2021-09-03
3789 Systematic and quantitative view of the antiviral arsenal of prokaryotes
Tesson, F.; Herve, A.; Touchon, M.; d'Humieres, C.; Cury, J.; Bernheim, A.
10.1101/2021.09.02.458658 — microbiology — Posted on 2021-09-03
3791 A MALDI-TOF assay identifies nilotinib as an inhibitor of inflammation in acute myeloid leukaemia
Marin-Rubio, J. L.; Heap, R. E.; Heunis, T.; Duenas, M. E.; Inns, J.; Scott, J.; Simpson, A. J.; Allan, J. M.; Blair, H.; Heidenreich, O.; Saxty, B.; Trost, M.
10.1101/2021.03.29.437557 — cancer biology — Posted on 2021-09-03
3794 Deep integrative models for large-scale human genomics
Sigurdsson, A. I.; Westergaard, D.; Winther, O.; Lund, O.; Brunak, S.; Vilhjalmsson, B. J.; Rasmussen, S.
10.1101/2021.06.11.447883 — bioinformatics — Posted on 2021-09-03
3796 singlecellVR: interactive visualization of single-cell data in virtual reality
Stein, D. F.; Chen, H.; Vinyard, M. E.; Qin, Q.; Combs, R. D.; Zhang, Q.; Pinello, L.
10.1101/2020.07.30.229534 — genomics — Posted on 2021-09-03
3803 Unmasking the cryptic immunopeptidome of EZH2 mutated diffuse large B-cell lymphomas through combination drug treatment
Bourne, C. M.; Mun, S. S.; Dao, T.; Aretz, Z. E. H.; Gejman, R. S.; Daman, A.; Takata, K.; Steidl, C.; Klatt, M. G.; Scheinberg, D. A.
10.1101/2021.09.01.458572 — immunology — Posted on 2021-09-03
3804 Glial TGFβ activity promotes axon survival in peripheral nerves
Lassetter, A.; Corty, M.; Barria, R.; Sheehan, A.; Aicher, S.; Fox, A. N.; Hill, J.; Freeman, M.
10.1101/2021.09.02.458753 — neuroscience — Posted on 2021-09-03
3805 singlecellVR: interactive visualization of single-cell data in virtual reality
Stein, D. F.; Chen, H.; Vinyard, M. E.; Combs, R. D.; Pinello, L.; Qin, Q.; Zhang, Q.
10.1101/2020.07.30.229534 — genomics — Posted on 2021-09-03
3806 Genetic coupling of life-history and aerobic performance in Atlantic salmon indicates potential constrains on life-history evolution
Prokkola, J. M.; Asheim, E. R.; Morozov, S.; Bangura, P.; Erkinaro, J.; Ruokolainen, A.; Primmer, C. R.; Aykanat, T.
10.1101/2021.08.23.457324 — evolutionary biology — Posted on 2021-09-03
3808 Mpe1 senses the polyadenylation signal in pre-mRNA to control cleavage and polyadenylation
Rodriguez-Molina, J. B.; O'Reilly, F. J.; Sheekey, E.; Maslen, S.; Skehel, J. M.; Rappsilber, J.; Passmore, L. A.
10.1101/2021.09.02.458805 — molecular biology — Posted on 2021-09-03
3810 RORγt-Expressing Pathogenic CD4+T Cells Cause Brain Inflammation During Chronic Colitis
Basu, R.; Mickael, M. E.; Bhaumik, S.; Chakraborti, A.; Umfress, A.; van Groen, T.; Macaluso, M.; Totenhagen, J.; Sorace, A. G.; Bibb, J. A.; Standaert, D. G.
10.1101/2021.09.01.458634 — immunology — Posted on 2021-09-03
3811 Elucidating the neural mechanisms of Learning-to-Learn
Goudar, V.; Peysakhovich, B.; Freedman, D. J.; Buffalo, E. A.; Wang, X.-J.
10.1101/2021.09.02.455707 — neuroscience — Posted on 2021-09-02
3812 Whole-brain studies of spontaneous behavior in head-fixed rats enabled by zero echo time MB-SWIFT fMRI
Paasonen, J.; Stenroos, P.; Laakso, H.; Pirttimaki, T.; Paasonen, E.; Salo, R. A.; Tanila, H.; Idiyatullin, D.; Garwood, M.; Michaeli, S.; Mangia, S.; Grohn, O.
10.1101/2021.06.15.448321 — neuroscience — Posted on 2021-09-03
3818 Spatial proteomics reveals profound subcellular reorganization in human keratinocytes exposed to UVA light
Valerio, H. P.; Ravagnani, F. G.; Candela, A. P. Y.; da Costa, B. D. C.; Ronsein, G. E.; Di Mascio, P.
10.1101/2021.09.01.458617 — biochemistry — Posted on 2021-09-02
3822 Multiplex spatial systems analysis of local nanodose drug responses predicts effective treatment combinations of immunotherapies and targeted agents in mammary carcinoma
Tatarova, Z.; Blumberg, D. C.; Korkola, J. E.; Heiser, L. M.; Muschler, J. L.; Schedin, P. J.; Ahn, S. W.; Mills, G. B.; Coussens, L. M.; Jonas, O.; Gray, J. W.
10.1101/2021.09.01.458631 — cancer biology — Posted on 2021-09-02
3823 Redox-dependent Structure and Dynamics of Macrophage Migration Inhibitory Factor Reveal Sites of Latent Allostery
Skeens, E.; Gadzuk-Shea, M. M.; Shah, D.; Bhandari, V.; Schweppe, D. K.; Berlow, R. B.; Lisi, G. P.
10.1101/2021.09.01.458630 — biophysics — Posted on 2021-09-02
3824 Nanomolar, noncovalent antagonism of hedgehog cholesterolysis: exception to the irreversibility rule for protein autoprocessing inhibition.
Wagner, A. G.; Stagnitta, R. T.; Xu, Z.; Pezzullo, J.; Kandel, N.; Covey, D. F.; Giner, J.-L.; Wang, C.; Callahan, B. P.
10.1101/2021.09.01.458638 — biochemistry — Posted on 2021-09-02
3825 Differential regulation of mouse hippocampal gene expression sex differences by chromosomal content and gonadal sex
Ocanas, S. R.; Ansere, V. A.; Tooley, K. B.; Hadad, N.; Chucair-Elliott, A. J.; Stanford, D. R.; Rice, S.; Wronowski, B.; Hoffman, J. M.; Austad, S. N.; Stout, M. B.; Freeman, W. M.
10.1101/2021.09.01.458115 — genomics — Posted on 2021-09-02
3826 Fine mapping spatiotemporal mechanisms of genetic variants underlying cardiac traits and disease
D'Antonio, M.; Arthur, T. D.; Nguyen, J. P.; Matsui, H.; D'Antonio-Chronowska, A.; Frazer, K. A.
10.1101/2021.09.01.458619 — genetics — Posted on 2021-09-02
3828 microRNAs as Indicators into the Causes and Consequences of Whole Genome Duplication Events
Peterson, K. J.; Beavan, A.; Chabot, P.; McPeek, M. L.; Pisani, D.; Fromm, B.; Simakov, O.
10.1101/2021.09.01.458616 — evolutionary biology — Posted on 2021-09-02
3829 Changes in antennal gene expression underlying sensory system maturation in Rhodnius prolixus
Estivalis, J. M. L.; Grosse-Wilde, E.; Fernandes, G. R.; Hansson, B. S.; Lorenzo, M. G.
10.1101/2021.09.02.458747 — molecular biology — Posted on 2021-09-02
3833 Screening and Identification of Lujo Virus Entry Inhibitors from an FDA-Approved Drugs Library
Cao, J.; Liu, Y.; Dong, S.; Zhou, M.; Guo, J.; Jia, X.; Zhang, Y.; Hou, Y.; Xiao, G.; Wang, W.
10.1101/2021.09.01.458657 — microbiology — Posted on 2021-09-02
3834 Human IL-10-producing B cells have diverse states induced from multiple B cell subsets
Glass, M. C.; Glass, D. R.; Oliveria, J. P.; Mbiribindi, B.; Esquivel, C. O.; Krams, S. M.; Bendall, S. C.; Martinez, O. M.
10.1101/2021.09.01.458645 — immunology — Posted on 2021-09-02
3837 Horizontal mitochondrial transfer from the microenvironment increases glioblastoma tumorigenicity
Watson, D. C.; Bayik, D.; Williford, S. E.; Lauko, A.; Zhou, Y.; Deshpande, G.; Seder, J.; Mears, J. A.; Cheng, F.; Hjelmeland, A. B.; Lathia, J. D.
10.1101/2021.09.01.458565 — cancer biology — Posted on 2021-09-02
3838 The ultrasound guide: katydid ear pinnae code for bat call detection
Pulver, C.; Celiker, E.; Woodrow, C.; Geipel, I.; Soulsbury, C.; Cullen, D.; Veitch, D.; Montealegre-Z, F.
10.1101/2021.09.01.458595 — biophysics — Posted on 2021-09-02
3840 Molecular Organization of the Early Stages of Nucleosome Phase Separation Visualized by Cryo-Electron Tomography
Zhang, M.; Diaz-Celis, C. D.; Onoa, B.; Canari-Chumpitaz, C.; Requejo, K. I.; Liu, J.; Vien, M.; Nogales, E.; Ren, G.; Bustamante, C.
10.1101/2021.09.01.458650 — biophysics — Posted on 2021-09-02
3843 Structural and Biochemical Rationale for Enhanced Spike Protein Fitness in Delta and Kappa SARS-CoV-2 Variants
Saville, J. W.; Mannar, D.; Zhu, X.; Srivastava, S. S.; Berezuk, A. M.; Demers, J.-P.; Zhou, S.; Tuttle, K.; Sekirov, I.; Kim, A.; Li, W.; Dimiter, D. S.; Subramaniam, S.
10.1101/2021.09.02.458774 — biochemistry — Posted on 2021-09-02
3845 The chromatin organization of a chlorarachniophyte nucleomorph genome
Marinov, G. K.; Chen, X. J.; Wu, T.; He, C.; Grossman, A. R.; Kundaje, A.; Greenleaf, W.
10.1101/2021.09.01.458626 — genomics — Posted on 2021-09-02
3848 Systematic and quantitative view of the antiviral arsenal of prokaryotes
Tesson, F.; Herve, A.; Touchon, M.; d'Humieres, C.; Cury, J.; Bernheim, A.
10.1101/2021.09.02.458658 — microbiology — Posted on 2021-09-02
3850 In vitro antimicrobial and cytotoxic activity of Lippia origanoides essential oil against bacteria of potential health concern
Quiguanas Guarin, E. S.; Agudelo, J. P. B.; Lopez-Carvajal, J. E.; Tabares, Y. A. R.; Sanabria, L. P.; Castano-Osorio, J. C.
10.1101/2021.09.02.458771 — microbiology — Posted on 2021-09-02
3854 Secretory MPP3 reinforce myeloid differentiation trajectory and amplify myeloid cell production
Kang, Y.-A.; Paik, H.; Zhang, S. Y.; Chen, J.; Warr, M. R.; Fan, R.; Passegue, E.
10.1101/2021.09.01.458573 — immunology — Posted on 2021-09-02
3855 Investigating molecular crowding during cell division in budding yeast with FRET
Lecinski, S.; Shepherd, J.; Frame, L.; Hayton, I.; MacDonald, C.; Leake, M. C.
10.1101/2021.07.29.454334 — biophysics — Posted on 2021-09-02
3856 RNA secondary structure packages evaluated and improved by high-throughput experiments
Wayment-Steele, H. K.; Kladwang, W.; Strom, A. I.; Lee, J.; Treuille, A.; Eterna Participants, ; Das, R.
10.1101/2020.05.29.124511 — biophysics — Posted on 2021-09-02
3858 Sustained software development, not number of citations or journal choice, is indicative of accurate bioinformatic software
Gardner, P. P.; Paterson, J. M.; McGimpsey, S. R.; Ashari Ghomi, F.; Umu, S. U.; Pawlik, A.; Gavryushkin, A.; Black, M. A.
10.1101/092205 — bioinformatics — Posted on 2021-09-02
3859 Mutant alleles differentially shape cattle complex traits and fitness
Xiang, R.; Breen, E.; Bolormaa, S.; Vander Jagt, C.; Chamberlain, A.; Macleod, I.; Goddard, M.
10.1101/2021.04.19.440546 — genomics — Posted on 2021-09-02
3860 Deciphering Multi-way Interactions in the Human Genome
Lindsly, S. M.; Chen, C.; Dilworth, S.; Jeyarajan, S.; Stansbury, C.; Cicalo, A.; Meixner, W.; Beckloff, N.; Ryan, C.; Surana, A.; Wicha, M.; Muir, L.; Rajapakse, I.
10.1101/2021.08.15.456363 — genomics — Posted on 2021-09-02
3861 Parallel introgression, not recurrent emergence, explains apparent elevational ecotypes of polyploid Himalayan snowtrout
Chafin, T. K.; Regmi, B.; Douglas, M. R.; Edds, D. R.; Wangchuk, K.; Dorji, S.; Norbu, P.; Norbu, S.; Changlu, C.; Khanal, G. P.; Tshering, S.; Douglas, M. E.
10.1101/2021.04.16.440204 — evolutionary biology — Posted on 2021-09-02
3862 Harbor porpoise losing its edges: genetic time series suggests a rapid population decline in Iberian waters over the last 30 years
Ben Chehida, Y.; Stelwagen, T.; Hoekendijk, J. P. A.; Ferreira, M.; Eira, C.; Pereira, A. T.; Nicolau, L.; Thumloup, J.; Fontaine, M. C.
10.1101/2021.08.19.456945 — evolutionary biology — Posted on 2021-09-02
3864 The ataxia protein sacsin is required for integrin trafficking and synaptic organization
Romano, L. E. L.; Aw, W. Y.; Hixson, K. M.; Novoselova, T. V.; Havener, T. M.; Howell, S.; Hall, C. L.; Xing, L.; Beri, J.; Nethisinghe, S.; Perna, L.; Hatimy, A.; Chioccioli Altadonna, G.; Graves, L. M.; Herring, L. E.; Hickey, A. J.; Thalassinos, K.; Chapple, J. P.; Wolter, J. M.
10.1101/2021.08.20.456807 — cell biology — Posted on 2021-09-02
3869 Mapping the peptide binding groove of MHC class I
Kopicki, J.-D.; Saikia, A.; Niebling, S.; Günther, C.; Garcia-Alai, M. M.; Springer, S.; Uetrecht, C.
10.1101/2021.08.12.455998 — biophysics — Posted on 2021-09-02
3875 PAK1 and PAK2 in cell metabolism regulation
Koranova, T.; Dvoracek, L.; Grebenova, D.; Roselova, P.; Obr, A.; Kuzelova, K.
10.1101/2021.05.18.444625 — cell biology — Posted on 2021-09-02
3876 HIV proviral burden, genetic diversity and dynamics in viremic controllers who subsequently initiated suppressive antiretroviral therapy
Omondi, F. H.; Sudderuddin, H.; Shahid, A.; Kinloch, N. N.; Jones, B. R.; Miller, R. L.; Tsai, O.; MacMillan, D.; Trocha, A.; Brockman, M. A.; Brumme, C. J.; Joy, J. B.; Liang, R.; Walker, B. D.; Brumme, Z. L.
10.1101/2021.03.29.437632 — microbiology — Posted on 2021-09-02
3877 Single-domain antibodies for targeting, detection and in vivo imaging of human CD4+ cells
Traenkle, B.; Kaiser, P. D.; Pezzana, S.; Richardson, J.; Gramlich, M.; Wagner, T. R.; Seyfried, D.; Weldle, M.; Holz, S.; Parfyonova, Y.; Schaller, M.; Nueske, S.; Scholz, A.; Zeck, A.; Jakobi, M.; Schneiderhan-Marra, N.; Maurer, A.; Gouttefangeas, C.; Kneilling, M.; Pichler, B. J.; Sonanini, D.; Rothbauer, U.
10.1101/2021.07.02.450848 — immunology — Posted on 2021-09-02
3878 Choice-selective sequences dominate in cortical relative to thalamic inputs to the nucleus accumbens, providing a potential substrate for credit assignment
Parker, N. F.; Baidya, A.; Cox, J.; Haetzel, L.; Zhukovskaya, A.; Murugan, M.; Engelhard, B.; Goldman, M. S.; Witten, I. B.
10.1101/725382 — neuroscience — Posted on 2021-09-02
3881 Event-Related Variability is Modulated by Task and Development
Naik, S.; Adibpour, P.; Dubois, J.; Dehaene-Lambertz, G.; Battaglia, D.
10.1101/2021.03.07.434162 — neuroscience — Posted on 2021-09-02
3885 A musculoskeletal finite element model of rat knee joint for evaluating cartilage biomechanics during gait
Orozco, G. A.; Karjalainen, K.; Moo, E. K.; Stenroth, L.; Tanska, P.; Rios, J. L.; Tuomainen, T. V.; Nissi, M. J.; Isaksson, H.; Herzog, W.; Korhonen, R. K.
10.1101/2021.09.01.458496 — bioengineering — Posted on 2021-09-02
3890 Gut microbiome and its cofactors are linked tolipoprotein distribution profiles
Castro Mejia, J.; Khakimov, B.; Lind, M.; Garne, E.; Paulova, P.; Tavakkoli, E. T.; Hansen, L.; Smilde, A. K.; Holm, L.; Engelsen, S. B.; Nielsen, D. S.
10.1101/2021.09.01.458531 — systems biology — Posted on 2021-09-02
3892 Macrophages induce inflammation by efferocytosis of apoptotic prostate cancer cells via HIF-1α stabilization
Mendoza-Reinoso, V.; Schnepp, P. M.; Baek, D. Y.; Rubin, J. R.; Schipani, E.; Keller, E. T.; McCauley, L. K.; Roca, H.
10.1101/2021.09.02.458687 — cancer biology — Posted on 2021-09-02
3893 ACKR3 induces the perturbation of rRNA biogenesis: a novel mechanism of colorectal tumorigenesis
Qu, X. J.; Yang, J.; Li, Y.-N.; Pan, T.; Miao, R.-R.; Zhang, Y.-Y.; Wu, S.-H.; Cui, S.-X.
10.1101/2021.09.01.458501 — cancer biology — Posted on 2021-09-02
3897 Transendothelial migration induces differential migration dynamics of leukocytes in tissue matrix
van Steen, A. C. I.; Kempers, L.; Schoppmeyer, R.; Blokker, M.; Beebe, D. J.; Nolte, M. A.; van Buul, J. D.
10.1101/2021.09.02.458715 — cell biology — Posted on 2021-09-02
3898 A GID E3 ligase assembly ubiquitinates an Rsp5 E3 adaptor and regulates plasma membrane transporters
Langlois, C. R.; Beier, V.; Karayel, O.; Chrustowicz, J.; Sherpa, D.; Mann, M.; Schulman, B.
10.1101/2021.09.02.458684 — cell biology — Posted on 2021-09-02
3899 Nanobody-Functionalized Cellulose for Capturing and Containing SARS-CoV-2
Sun, X.; Yang, S.; Al-Dossary, A.; Broitman, S.; Ni, Y.; Yang, M.; Li, J.
10.1101/2021.09.01.458653 — bioengineering — Posted on 2021-09-02
3900 High diversity in Delta variant across countries revealed via genome-wide analysis of SARS-CoV-2 beyond the Spike protein
Ghosh, P.; Suratekar, R.; Niesen, M. J. M.; Anand, P.; Donadio, G.; Soundararajan, V.; Venkatakrishnan, A.
10.1101/2021.09.01.458647 — genomics — Posted on 2021-09-02
3901 Azacytidine targeting SARS-CoV-2 viral RNA as a potential treatment for COVID-19
Lin, X.; Ke, X.; Lin, X.; Zhang, T.; Xiong, H.; Zhao, B.; Liu, W.; Chen, Q.; Tang, C.
10.1101/2021.09.01.458475 — microbiology — Posted on 2021-09-02
3906 Glass Half Full: Preserved Anatomical Bypasses Predict Variance in Language Functions After Stroke
Erickson, B. A.; Kim, B.; Deck, B.; Pustina, D.; DeMarco, A. T.; Dickens, J. V.; Kelkar, A.; Turkeltaub, P.; Medaglia, J.
10.1101/2021.08.31.458462 — neuroscience — Posted on 2021-09-02
3907 Real-time visualization of mRNA synthesis during memory formation in live animals
Lee, B. H.; Shim, J. Y.; Moon, H. C.; Kim, D. W.; Kim, J.; Yook, J. S.; Kim, J.; Park, H. Y.
10.1101/2021.09.01.458476 — neuroscience — Posted on 2021-09-02
3913 Optical and computational dissection of emergent prefrontal rewiring to encode fear memory
Agetsuma, M.; Sato, I.; Tanaka, Y. R.; Carrillo-Reid, L.; Kasai, A.; Arai, Y.; Yoshitomo, M.; Hashimoto, H.; Nabekura, J.; Nagai, T.
10.1101/2021.08.31.458461 — neuroscience — Posted on 2021-09-02
3915 Impact of charge patches on tumor disposition and biodistribution of therapeutic antibodies
Stueber, J. C.; Rechberger, K. F.; Miladinovic, S. M.; Poeschinger, T.; Zimmermann, T.; Villenave, R.; Eigenmann, M. J.; Kraft, T. E.; Shah, D. K.; Kettenberger, H.; Richter, W. F.
10.1101/2021.09.01.458024 — cancer biology — Posted on 2021-09-02
3917 Phylogenetic analysis of molecular pathways in Tregs Suppressor Function
Mickael, M. E.; Kubick, N.; Bhaumik, S.; Horbanczuk, J. O.; Sacharczuk, M.; Basu, R.
10.1101/2021.07.30.453759 — evolutionary biology — Posted on 2021-09-02
3918 Widespread latitudinal asymmetry in marginal population performance
Pulido, F.; Castagneyrol, B.; Rodriguez-Sanchez, F.; Caceres, Y.; Pardo, A.; Moracho, E.; Kollmann, J.; Valladares, F.; Ehrlen, J.; Jump, A. S.; Svenning, J.-C.; Hampe, A.
10.1101/529560 — ecology — Posted on 2021-09-02
3919 Yap/Taz-Activated Tert-Expressing Acinar Cells Are Required for Pancreatic Regeneration
Suh, H. N.; Kim, M. J.; Lee, S. H.; Jun, S.; Zhang, J.; Johnson, R. L.; Park, J.-I.
10.1101/2021.08.30.458292 — cell biology — Posted on 2021-09-02
3920 Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states
Triana, S. H.; Vonficht, D.; Jopp-Saile, L.; Raffel, S.; Lutz, R.; Leonce, D. R.; Antes, M.; Hernandez-Malmierca, P.; Ordonez-Rueda, D.; Ramasz, B.; Boch, T.; Jann, J.-C.; Nowak, D.; Hofmann, W.-K.; Muller-Tidow, C.; Huebschmann, D.; Alexandrov, T.; Benes, V.; Trumpp, A.; Paulsen, M.; Velten, L.; Haas, S.
10.1101/2021.03.18.435922 — immunology — Posted on 2021-09-02
3926 Natural variation in Arabidopsis ISR1 affects iron localization and induced systemic resistance
Socha, A.; Song, Y.; Ross, B.; Bush, J.; Ausubel, F. M.; Guerinot, M. L.; Haney, C. H.
10.1101/2021.09.01.458588 — plant biology — Posted on 2021-09-02
3927 A genetically linked pair of NLR immune receptors show contrasting patterns of evolution
Shimizu, M.; Hirabuchi, A.; Sugihara, Y.; Abe, A.; Takeda, T.; Kobayashi, M.; Hiraka, Y.; Kanzaki, E.; Oikawa, K.; Saitoh, H.; Langner, T.; Banfield, M. J.; Kamoun, S.; Terauchi, R.
10.1101/2021.09.01.458560 — plant biology — Posted on 2021-09-02
3929 APC-mutant cells exploit compensatory chromosome alterations to restore tumour cell fitness
Kawasaki, Y.; Hamaji, T.; Owada, K.; Hayashi, A.; Wu, Y.; Nogi, T.; Okada, M.; Sakai, S.; Tokushige, N.; Kouyama, Y.; Niida, A.; Mimori, K.; Kuroda, T.; Senda, T.; Ohsugi, M.; Fumoto, K.; Kikuchi, A.; Widlund, P. O.; Kiyosue, K.; Yamashita, N.; Morita, M.; Yokota, H.; Arjunan, S. N. V.; Chew, W.-X.; Takahashi, K.; Legant, W. R.; Chen, B.-C.; Betzig, E.; Smits, R.; Fodde, R.; Oshima, H.; Oshima, M.; Taketo, M. M.; Akiyama, T.; Mimori-Kiyosue, Y.
10.1101/2020.09.18.303016 — cell biology — Posted on 2021-09-02
3934 Community Evaluation of Glycoproteomics Informatics Solutions Reveals High-Performance Search Strategies of Serum N- and O-Glycopeptide Data
Kawahara, R.; Chernykh, A.; Alagesan, K.; Bern, M.; Cao, W.; Chalkley, R. J.; Cheng, K.; Choo, M. S.; Edwards, N.; Goldman, R.; Hoffmann, M.; Hu, Y.; Huang, Y.; Kim, J. Y.; Kletter, D.; Liquet-Weiland, B.; Liu, M.; Mechref, Y.; Meng, B.; Neelamegham, S.; Nguyen-Khuong, T.; Nilsson, J.; Pap, A.; Park, G. W.; Parker, B. L.; Pegg, C. L.; Penninger, J. M.; Phung, T. K.; Pioch, M.; Rapp, E.; Sakalli, E.; Sanda, M.; Schulz, B. L.; Scott, N. E.; Sofronov, G.; Stadlmann, J.; Vakhrushev, S. Y.; Woo, C. M.; Wu, H.-Y.; Yang, P.; Ying, W.; Zhang, H.; Zhang, Y.; Zhao, J.; Zaia, J.; Haslam, S. M.; Palmisano
10.1101/2021.03.14.435332 — biochemistry — Posted on 2021-09-02
3939 Domestication Reshaped the Genetic Basis of Inbreeding Depression in a Maize Landrace Compared to its Wild Relative, Teosinte
Holland, J. B.; Samayoa, L. F.; Olukolu, B. A.; Yang, C. J.; Chen, Q.; Stetter, M. G.; York, A. M.; Sanchez-Gonzalez, J. d. J.; Glaubitz, J. C.; Bradbury, P. J.; Romay, M. C.; Sun, Q.; Yang, J.; Ross-Ibarra, J.; Buckler, E. S.; Doebley, J. F.
10.1101/2021.09.01.458502 — evolutionary biology — Posted on 2021-09-02
3940 Environmental filtering in marine fish communities is weakened during severe hypoxia season
Shinohara, N.; Hongo, Y.; Ichinokawa, M.; Nishijima, S.; Sawayama, S.; Kurogi, H.; Uto, Y.; Mita, H.; Ishii, M.; Kusano, A.; Akimoto, S.
10.1101/2021.04.29.442042 — ecology — Posted on 2021-09-02
3943 Parasite-probiotic interactions in the gut: Bacillus sp. and Enterococcus faecium regulate type-2 inflammatory responses and modify the gut microbiota of pigs during helminth infection
Myhill, L. J.; Stolzenbach, S.; Mejer, H.; Krych, L.; Jakobsen, S. R.; Kot, W.; Skovgaard, K.; Canibe, N.; Nejsum, P.; Nielsen, D. S.; Thamsborg, S. M.; Williams, A. R.
10.1101/2021.09.01.458597 — microbiology — Posted on 2021-09-02
3945 Intrusive Experiences In Post-Traumatic Stress Disorder: Treatment Response Induces Changes In The Effective Connectivity Of The Anterior Insula
Leroy, A.; Very, E.; Birmes, P.; Szaffarczyk, S.; Lopes, R.; Faure, C.; Duhem, S.; Grandgenevre, P.; Warembourg, F.; Vaiva, G.; Jardri, R.
10.1101/2020.10.01.319269 — neuroscience — Posted on 2021-09-02
3947 Dynamical processing of orientation precision in the primary visual cortex
Ladret, H. J.; Cortes, N.; Ikan, L.; Chavane, F.; Casanova, C.; Perrinet, L. U.
10.1101/2021.03.30.437692 — neuroscience — Posted on 2021-09-02
3948 α-catenin switches between a slip and an asymmetric catch bond with F-actin to cooperatively regulate cell junction fluidity
Arbore, C.; Sergides, M.; Gardini, L.; Bianchi, G.; Kashchuk, A. V.; Pertici, I.; Bianco, P.; Pavone, F. S.; Capitanio, M.
10.1101/2020.04.15.035527 — biophysics — Posted on 2021-09-02
3949 Dynamic assembly of the calcium hemostasis modulator 1 channel gates ATP permeation
Ren, Y.; Li, Y.; Wang, Y.; Wen, T.; Lu, X.; Chang, S.; Zhang, X.; Shen, Y.; Yang, X.
10.1101/2021.01.14.426634 — biochemistry — Posted on 2021-09-02
3950 Functional fluorescently-tagged human profilin
Pimm, M. L.; Liu, X.; Tuli, F.; Lojko, A.; Henty-Ridilla, J. L.
10.1101/2021.09.01.458557 — cell biology — Posted on 2021-09-02
3951 Spatial organization of nuclear pores in Xaenopus laevis oocytes
Ravazzano, L.; Bonfanti, S.; Guerra, R.; Montel, F.; La Porta, C. A. M.; Zapperi, S.
10.1101/2021.09.01.458492 — biophysics — Posted on 2021-09-02
3954 High-altitude adaptation and incipient speciation in geladas
Chiou, K. L.; Janiak, M. C.; Schneider-Crease, I.; Sen, S.; Ayele, F.; Chuma, I. S.; Knauf, S.; Lemma, A.; Signore, A. V.; D'Ippolito, A. M.; Abebe, B.; Haile, A. A.; Kebede, F.; Fashing, P. J.; Nguyen, N.; McCann, C.; Houck, M. L.; Wall, J. D.; Burrell, A. S.; Bergey, C. M.; Rogers, J.; Phillips-Conroy, J. E.; Jolly, C. J.; Melin, A. D.; Storz, J. F.; Lu, A.; Beehner, J. C.; Bergman, T. J.; Snyder-Mackler, N.
10.1101/2021.09.01.458582 — genomics — Posted on 2021-09-01
3955 Sites of active gene regulation in the prenatal frontal cortex and their role in neuropsychiatric disorders
Kouakou, M. R.; Cameron, D.; Hannon, E.; Dempster, E. L.; Mill, J.; Hill, M. J.; Bray, N. J.
10.1101/2021.09.01.458548 — genetics — Posted on 2021-09-01
3957 Tolerance of Pseudomonas Strain to the 2,4-D Herbicide through a Peroxidase System
Oliveira, E. P.; Rovida, A. F. d. S.; Martins, J. G.; Pileggi, S. A. V.; Schemczssen-Graeff, Z.; Pileggi, M.
10.1101/2021.09.01.458513 — microbiology — Posted on 2021-09-01
3958 Functional connectivity gradients as a common neural architecture for predictive processing in the human brain
Katsumi, Y.; Kamona, N.; Zhang, J.; Bunce, J. G.; Hutchinson, J. B.; Yarossi, M.; Tunik, E.; Quigley, K. S.; Dickerson, B. C.; Feldman Barrett, L.
10.1101/2021.09.01.456844 — neuroscience — Posted on 2021-09-01
3960 Biochemical characterisation of human transglutaminase 4
Csoban-Szabo, Z.; Becsi, B.; El Alaoui, S.; Fesus, L.; Korponay-Szabo, I. R.; Kiraly, R.
10.1101/2021.09.01.458359 — biochemistry — Posted on 2021-09-01
3961 Genome-wide association analysis of cotton salt stress response-related sites
Zhang, Z.; Zheng, J.; Gong, Z.; Liang, Y.; Sang, Z.; Xu, Y.; Li, X.; Wang, J.
10.1101/2021.09.01.458514 — genomics — Posted on 2021-09-01
3962 Update on the mosquito fauna (Diptera: Culicidae) distribution in Cabo Verde: occurrence of the species complexes Anopheles gambiae and Culex pipiens (pipiens, quinquefasciatus and their hybrids)
da Veiga Leal, S.; Varela, I. B. F.; Monteiro, D. D. S.; de Sousa, C. M. R.; Mendonca, M. d. L. L.; De Pina, A. J.; Goncalves, A. A. L.; Osorio, H. C.
10.1101/2021.09.01.458512 — ecology — Posted on 2021-09-01
3963 Meta-exoproteomics identifies active plant-microbe interactions operating in the rhizosphere
Lidbury, I. D. E. A.; Raguideau, S.; Lui, S.; Murphy, A.; Stark, R.; Borsetto, C.; Fraser, T.; Goodall, A.; Bottrill, A.; Jones, A. M. E.; Bending, G.; Tibbett, M.; Hammond, J.; Quince, C.; Scanlan, D.; Pandhal, J.; Wellington, E.
10.1101/2021.09.01.458574 — microbiology — Posted on 2021-09-01
3964 Generating heterokaryotic cells via bacterial cell-cell fusion
Shitut, S.; Shen, M.-J.; Claushuis, B.; Derks, R. J. E.; Giera, M.; Rozen, D.; Claessen, D.; Kros, A.
10.1101/2021.09.01.458600 — microbiology — Posted on 2021-09-01
3968 Parasite-probiotic interactions in the gut: Bacillus sp. and Enterococcus faecium regulate type-2 inflammatory responses and modify the gut microbiota of pigs during helminth infection
Myhill, L.; Stolzenbach, S.; Mejer, H.; Krych, L.; Jakobsen, S.; Kot, W.; Skovgaard, K.; Canibe, N.; Nejsum, P.; Nielsen, D. S.; Thamsborg, S.; Williams, A.
10.1101/2021.09.01.458597 — microbiology — Posted on 2021-09-01
3971 Systems analysis of the familial cardiomyopathy signaling network
Khalilimeybodi, A.; Omens, J. H.; McCulloch, A. D.; Saucerman, J. J.
10.1101/2021.08.28.458032 — systems biology — Posted on 2021-09-01
3972 Non-Newtonian Blood Rheology Impacts Left Atrial Stasis in Patient-Specific Simulations
Gonzalo, A.; Garcia-Villalba, M.; Rossini, L.; Duran, E.; Vigneault, D.; Martinez-Legazpi, P.; Flores, O.; Bermejo, J.; McVeigh, E.; Kahn, A.; del Alamo, J. C.
10.1101/2021.06.24.449801 — bioengineering — Posted on 2021-09-01
3974 De novo chromosome-length assembly of the mule deer (Odocoileus hemionus) genome
Lamb, S.; Taylor, A. M.; Hughes, T. A.; McMillan, B. R.; Larsen, R. T.; Khan, R.; Weisz, D.; Dudchenko, O.; Aiden, E. L.; Frandsen, P. B.
10.1101/2021.08.12.456132 — genomics — Posted on 2021-09-01
3975 Nuclear Pore Complex Acetylation Regulates mRNA Export and Cell Cycle Commitment in Budding Yeast
Gomar-Alba, M.; Pozharskaia, V.; Schaal, C.; Kumar, A.; Jacquel, B.; Charvin, G.; Igual, J. C.; Mendoza, M.
10.1101/2021.09.01.458533 — cell biology — Posted on 2021-09-01
3976 Dual perspective proteomics infectome profiling discovers Salmonella type III secretion system effector functions in macrophages
Geddes-McAlister, J.; Sukumaran, A.; Vogt, S. L.; Roland, J. L.; Woodward, S. E.; Muselius, B.; Gee, L.; Roach, E. J.; Khursigara, C. M.; Raupach, B.; Finlay, B. B.; Meissner, F.
10.1101/2021.09.01.458519 — microbiology — Posted on 2021-09-01
3977 Retrovirus-induced leukemia - hijack of T-cell activation mechanisms revealed by single-cell analysis
Tan, B. J. Y.; Sugata, K.; Reda, O.; Matsuo, M.; Uchiyama, K.; Miyazato, P.; Hahaut, V.; Yamagishi, M.; Uchimaru, K.; Suzuki, Y.; Ueno, T.; Suzushima, H.; Katsuya, H.; Tokunaga, M.; Uchiyama, Y.; Nakamura, H.; Sueoka, E.; Utsunomiya, A.; Ono, M.; Satou, Y.
10.1101/2021.09.01.458291 — microbiology — Posted on 2021-09-01
3978 A Shigella type 3 effector protein co-opts host inositol pyrophosphates for activity
Wood, T. E.; Yoon, J. M.; Eshleman, H. D.; Slade, D. J.; Lesser, C. F.; Goldberg, M. B.
10.1101/2021.09.01.458261 — microbiology — Posted on 2021-09-01
3980 Small proline-rich proteins 1 and 2 function as antimicrobial proteins in the skin
Zhang, C.; Hu, Z.; Lone, A. G.; Artami, M.; Edwards, M.; Stein, M.; Harris-Tryon, T. A.
10.1101/2021.09.01.458578 — immunology — Posted on 2021-09-01
3981 The Digital Brain Bank, an open access platform for post-mortem datasets
Tendler, B. C.; Hanayik, T.; Ansorge, O.; Bangerter-Christensen, S.; Berns, G. S.; Bertelsen, M. F.; Bryant, K. L.; Foxley, S.; van den Heuvel, M.; Howard, A. F. D.; Huszar, I.; Khrapitchev, A. A.; Leonte, A.; Manger, P. R.; Menke, R. A. L.; Mollink, J.; Mortimer, D.; Pallebage-Gamarallage, M.; Roumazeilles, L.; Sallet, J.; Scholtens, L. H.; Scott, C.; Smart, A.; Turner, M. R.; Wang, C.; Jbabdi, S.; Mars, R. B.; Miller, K. L.
10.1101/2021.06.21.449154 — neuroscience — Posted on 2021-09-01
3983 Partitioning variability in animal behavioral videos using semi-supervised variational autoencoders
Whiteway, M. R.; Biderman, D.; Friedman, Y.; Dipoppa, M.; Buchanan, E. K.; Wu, A.; Zhou, J.; Bonacchi, N.; Miska, N. J.; Noel, J.-P. R.; Rodriguez, E.; Schartner, M.; Socha, K.; Urai, A. E.; Salzman, C. D.; The International Brain Lab, ; Cunningham, J. P.; Paninski, L.
10.1101/2021.02.22.432309 — neuroscience — Posted on 2021-09-01
3984 Spectral fiber-photometry derives hemoglobin-absorption changes for accurate measurement of fluorescent sensor activity
Zhang, W.-T.; Chao, T.-H. H.; Yang, Y.; Wang, T.-W.; Lee, S.-H.; Oyarzabal, E. A.; Zhou, J.; Nonneman, R.; Pegard, N. C.; Zhu, H.; Cui, G.; Shih, Y.-Y. I.
10.1101/2021.08.23.457372 — neuroscience — Posted on 2021-09-01
3986 ChIPflow:from raw data to epigenomic dynamics
Daunesse, M.; Legendre, R.; Varet, H.; Pain, A.; Chica, C.
10.1101/2021.02.02.429342 — bioinformatics — Posted on 2021-09-01
3987 A modelling framework for the prediction of the herd-level probability of infection from longitudinal data
Madouasse, A.; Mercat, M.; van Roon, A.; Graham, D.; Guelbenzu, M.; Santman Berends, I.; van Schaik, G.; Nielen, M.; Frössling, J.; Agren, E.; Humphry, R.; Eze, J.; Gunn, G.; Henry, M. K.; Gethmann, J.; More, S. J.; Toft, N.; Fourichon, C.
10.1101/2020.07.10.197426 — bioinformatics — Posted on 2021-09-01
3990 Engineering genetically-encoded synthetic biomarkers for breath-based cancer detection
Vermesh, O.; D'Souza, A.; Alam, I. S.; Wardak, M.; McLaughlin, T.; El Rami, F.; Sathirachinda, A.; Bell, J. C.; James, M. L.; Hori, S. S.; Gross, E. R.; Gambhir, S. S.
10.1101/2021.09.01.456741 — bioengineering — Posted on 2021-09-01
3991 Spatial proteomics reveals profound subcellular reorganization in human keratinocytes exposed to UVA light
Valerio, H. P.; Ravagnani, F. G.; Candela, A. P. Y.; da Costa, B. D. C.; Ronsein, G. E.; Di Mascio, P.
10.1101/2021.09.01.458617 — biochemistry — Posted on 2021-09-01
3996 Mapping interindividual dynamics of innate immune response at single-cell resolution
Kumasaka, N.; Rostom, R.; Huang, N.; Polanski, K.; Meyer, K.; Patel, S.; Boyd, R.; Gomez, C.; Barnett, S.; Panousis, N.; Schwartzentruber, J.; Ghoussaini, M.; Lyons, P. A.; Calero-Nieto, F. J.; Göttgens, B.; Barnes, J. L.; Worlock, K. B.; Yoshida, M.; Nikolic, M.; Stephenson, E.; Reynolds, G.; Haniffa, M.; Marioni, J.; Stegle, O.; Hagai, T.; Teichmann, S. A.
10.1101/2021.09.01.457774 — genetics — Posted on 2021-09-01
3997 Rare coding variants in 35 genes associate with circulating lipid levels: a multi-ancestry analysis of 170,000 exomes
Hindy, G.; Dornbos, P.; Chaffin, M. D.; Liu, D. J.; Wang, M. X.; Selvaraj, M. S.; Zhang, D.; Park, J.; Aguilar-Salinas, C. A.; Antonacci-Fulton, L.; Ardissino, D.; Arnett, D. K.; Aslibekyan, S.; Atzmon, G.; Ballantyne, C. M.; Barajas-Olmos, F.; Barzilai, N.; Becker, L. C.; Bielak, L. F.; Bis, J. C.; Blangero, J.; Boerwinkle, E.; Bonnycastle, L. L.; Bottinger, E.; Bowden, D. W.; Bown, M. J.; Brody, J. A.; Broome, J. G.; Burtt, N. P.; Cade, B. E.; Centeno-Cruz, F.; Chan, E.; Chang, Y.-C.; Chen, Y.-D. I.; Cheng, C.-Y.; Choi, W. J.; Chowdhury, R.; Contreras-Cubas, C.; Cordova, E. J.; Correa, A.; C
10.1101/2020.12.22.423783 — genetics — Posted on 2021-09-01
3999 Evolution of thermal physiology alters projected species distributions under climate change
Wuitchik, S. J.; Mogensen, S.; Barry, T. N.; Paccard, A.; Jamniczky, H. A.; Barrett, R. D.; Rogers, S. M.
10.1101/2021.02.25.432865 — ecology — Posted on 2021-09-01
4001 The SWI/SNF chromatin remodeling assemblies BAF and PBAF differentially regulate cell cycle exit and cellular invasion in vivo
Smith, J. J.; Xiao, Y.; Parsan, N.; Medwig-Kinney, T. N.; Martinez, M. A. Q.; Moore, F. E. Q.; Palmisano, N. J.; Kohrman, A. Q.; Delos Reyes, M. C.; Adikes, R. C.; Liu, S.; Bracht, S. A.; Zhang, W.; Wen, K.; Kratsios, P.; Matus, D. Q.
10.1101/2021.03.01.433447 — developmental biology — Posted on 2021-09-01
4002 Inflammatory response in hematopoietic stem and progenitor cells triggered by activating SHP2 mutations potentiates leukemogenesis
Solman, M.; Blokzijl-Franke, S.; Piques, F.; Yan, C.; Yang, Q.; Strullu, M.; Kamel, S. M.; Ak, P.; Bakkers, J.; Langenau, D. M.; Cave, H.; den Hertog, J.
10.1101/2020.09.10.289090 — developmental biology — Posted on 2021-09-01
4003 Tiled-ClickSeq for targeted sequencing of complete coronavirus genomes with simultaneous capture of RNA recombination and minority variants
Jaworski, E.; Langsjoen, R. M.; Mitchell, B.; Judy, B.; Newman, P.; Zhou, Y.; Swetnam, D.; Sotcheff, S.; Morris, V.; Saada, N.; Machado, R.; McConnel, A.; Miller, A. L.; Plante, J. A.; Plante, K. S.; Dong, J.; Ren, P.; Ksiazek, T.; Menachery, V. D.; Weaver, S.; Routh, A. L.
10.1101/2021.03.10.434828 — molecular biology — Posted on 2021-09-01
4004 Artificial introns for effective expression of transgenes in mammalian cells
Naberezhnov, D. S.; Kirsanov, K. I.; Lesovaya, E. A.; Yakubovskaya, M. G.
10.1101/2021.09.01.457939 — molecular biology — Posted on 2021-09-01
4006 Gene signatures and host-parasite interactions revealed by dual single-cell profiling of Plasmodium vivax liver infection
Mancio-Silva, L.; Gural, N.; Wadsworth, M. H.; Butty, V. L.; Hughes, T. K.; March, S.; Nerurkar, N.; Roobsoong, W.; Fleming, H. E.; Whittaker, C.; Levine, S. S.; Sattabongkot, J.; Shalek, A. K.; Bhatia, S. N.
10.1101/2021.09.01.454555 — microbiology — Posted on 2021-09-01
4007 Long-term incubation of lake water enables genomic sampling of consortia involving Planctomycetes and Candidate Phyla Radiation bacteria
Jaffe, A. L.; Fuster, M.; Schoelmerich, M. C.; Chen, L.-X.; Colombet, J.; Billard, H.; Sime-Ngando, T.; Banfield, J.
10.1101/2021.09.01.458585 — microbiology — Posted on 2021-09-01
4010 A closed Candidatus Odinarchaeum genome exposes Asgard archaeal viruses
Tamarit, D.; Caceres, E. F.; Krupovic, M.; Nijland, R.; Eme, L.; Robinson, N. P.; Ettema, T. J. G.
10.1101/2021.09.01.458545 — microbiology — Posted on 2021-09-01
4014 Mixed Origins: HIV gp120-specific memory develops from pre-existing memory and naive B cells following vaccination in humans
Basu, M.; Piepenbrink, M. S.; Fucile, C.; Bunce, C. A.; Man, L.-X.; Liesveld, J.; Rosenberg, A. F.; Keefer, M. C.; Kobie, J. J.
10.1101/2021.09.01.458551 — immunology — Posted on 2021-09-01
4016 Human interictal epileptiform discharges are bidirectional traveling waves echoing ictal discharges
Smith, E. H.; Liou, J.-Y.; Merricks, E. M.; Davis, T. S.; Thomson, K.; Greger, B.; House, P. A.; Emerson, R.; Goodman, R. R.; McKhann, G. M.; Sheth, S. A.; Schevon, C. A.; Rolston, J. D.
10.1101/2021.04.28.440978 — neuroscience — Posted on 2021-09-01
4017 The SARS-CoV-2 spike (S) and the orthoreovirus p15 cause neuronal and glial fusion
Martinez-Marmol, R.; Giordano-Santini, R.; Kaulich, E.; Cho, A.-N.; Riyadh, M. A.; Robinson, E.; Balistreri, G.; Meunier, F. A.; Ke, Y. D.; Ittner, L. M.; Hilliard, M. A.
10.1101/2021.09.01.458544 — neuroscience — Posted on 2021-09-01
4018 Inferring differential subcellular localisation in comparative spatial proteomics using BANDLE
Crook, O.; Davies, C. T. R.; Breckels, L.; Christopher, J.; Gatto, L.; Kirk, P. D.; Lilley, K. S.
10.1101/2021.01.04.425239 — systems biology — Posted on 2021-09-01
4020 Measuring hidden phenotype: Quantifying the shape of barley seeds using the Euler Characteristic Transform
Amezquita, E. J.; Quigley, M. Y.; Ophelders, T.; Landis, J. B.; Koenig, D.; Munch, E.; Chitwood, D. H.
10.1101/2021.03.27.437348 — plant biology — Posted on 2021-09-01
4021 β-RA targets mitochondrial metabolism and adipogenesis, leading to therapeutic benefits against CoQ deficiency and age-related overweight
Hidalgo-Gutierrez, A.; Barriocanal-Casado, E.; Diaz-Casado, M. E.; Gonzalez-Garcia, P.; Zenezini Chiozzi, R.; Acuna-Castroviejo, D.; Lopez, L. C.
10.1101/2021.04.13.438670 — physiology — Posted on 2021-09-01
4023 CRISPR-SID: identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping
Naert, T.; Tulkens, D.; Van Nieuwenhuysen, T.; Przybyl, J.; Demuynck, S.; van de Rijn, M.; Al Jazrawe, M.; Alman, B.; Coucke, P. J.; De Leeneer, K.; Vanhove, C.; Savvides, S. N.; Creytens, D.; Vleminckx, K.
10.1101/595769 — cancer biology — Posted on 2021-09-01
4026 THUNDER: A reference-free deconvolution method to infer cell type proportions from bulk Hi-C data
Rowland, B.; Huh, R.; Hou, Z.; Wen, J.; Shen, Y.; Hu, M.; Giusti-Rodriguez, P.; Sullivan, P. F.; Li, Y.
10.1101/2020.11.12.379941 — bioinformatics — Posted on 2021-09-01
4027 Injectable Nanoparticle-Based Hydrogels Enable the Safe and Effective Deployment of Immunostimulatory CD40 Agonist Antibodies
Correa, S.; Gale, E. C.; Mayer, A. T.; Xiao, Z.; Liong, C.; Klich, J. H.; Brown, R. A.; Meany, E. L.; Saouaf, O. M.; Maikawa, C. L.; Grosskopf, A. K.; Mann, J. L.; Idoyaga, J.; Appel, E.
10.1101/2021.06.27.449987 — bioengineering — Posted on 2021-09-01
4028 Tapping into a phospholipid-LRH-1 axis yields a powerful anti-inflammatory agent with in vivo activity against colitis
Mays, S. G.; D'Agostino, E. H.; Flynn, A. R.; Huang, X.; Wang, G.; Liu, X.; Millings, E. J.; Okafor, C. D.; Patel, A.; Cato, M. L.; Cornelison, J. L.; Melchers, D.; Houtman, R.; Moore, D. D.; Calvert, J. W.; Jui, N. T.; Ortlund, E. A.
10.1101/2020.09.01.278291 — biochemistry — Posted on 2021-09-01
4032 Interfered Chromosome Pairing Promotes Meiosis Instability of Autotetraploid Arabidopsis by High Temperatures
Fu, H.; Zhao, J.; Ren, Z.; Yang, K.; Wang, C.; Zhang, X.; Elesawi, I. E.; Zhang, X.; Xia, J.; Chen, C.; Lu, P.; Chen, Y.; Liu, H.; Yu, G.; Liu, B.
10.1101/2021.08.31.458414 — plant biology — Posted on 2021-09-01
4037 Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats
Kucharska, I.; Hossain, L.; Ivanochko, D.; Yang, Q.; Rubinstein, J. L.; Pomes, R.; Julien, J.-P.
10.1101/2021.08.31.458469 — molecular biology — Posted on 2021-09-01
4038 Strain-dependent selective antimicrobial action of cationic polyelectrolytes on Gram-negative bacteria
Rybkin, I.; Mirtic, J.; Majaron, H.; Hrescak, J.; Ceh, M.; Strancar, J.; Kristl, J.; Rijavec, T.; Lapanje, A.
10.1101/2021.08.31.458386 — microbiology — Posted on 2021-09-01
4039 Absence of severe COVID-19 in patients with clonal mast cells activation disorders: effective anti-SARS-CoV-2 immune response.
Rossignol, J.; Ouedrani, A.; Bulai-Livideanu, C.; Barete, S.; Terriou, L.; Launay, D.; Lemal, R.; Greco, C.; Frenzel, L.; Meni, C.; Bodemere-Skandalis, C.; Polivka, L.; Collange, A.-F.; Hachichi, H.; Bouzourine, S.; Nait Messaoud, D.; Negretto, M.; Vendrame, L.; Jambou, M.; Gousseff, M.; Durupt, S.; Lega, J.-C.; Durand, J.-M.; GAUDY, C.; Damaj, G.; Gourin, M.-P.; Hamidou, M.; Bouillet, L.; Le Mouel, E.; Maria, A.; Zunic, P.; Cabrera, Q.; Vincent, D.; Lavigne, C.; Riviere, E.; Gourguechon, C.; Brignier, A.; Lhermitte, L.; Molina, T. J.; BRUNEAU, J.; Agopian, J.; Dubreuil, P.; Ranta, D.; Mania,
10.1101/2021.09.01.458516 — immunology — Posted on 2021-09-01
4040 Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity reduces lung inflammation
Van Rompay, K. K. A.; Olstad, K. J.; Sammak, R. L.; Dutra, J.; Watanabe, J. K.; Usachenko, J. L.; Immareddy, R.; Roh, J. W.; Verma, A.; Shaan Lakshmanappa, Y.; Schmidt, B.; Di Germanio, C.; Rizvi, N.; Stone, M.; Simmons, G.; Dumont, L.; Allen, A. M.; Lockwood, S.; Pollard, R. E.; Ramiro De Assis, R.; Yee, J. L.; Nham, P. B.; Ardeshir, A. A.; Deere, J. D.; Patterson, J.; Jain, A.; Felgner, P. L.; Iyer, S. S.; Hartigan-O'Connor, D. J.; Busch, M. P.; Reader, J. R.
10.1101/2021.09.01.458520 — immunology — Posted on 2021-09-01
4041 Refining epileptogenic high-frequency oscillations using deep learning: a reverse engineering approach
Zhang, Y.; Lu, Q.; Monsoor, T.; Hussain, S. A.; Qiao, J. X.; Salamon, N.; Fallah, A.; Sim, M. S.; ASANO, E.; Sankar, R.; Staba, R. J.; Engel, J.; Speier, W.; Roychowdhury, V.; Nariai, H.
10.1101/2021.08.31.458385 — neuroscience — Posted on 2021-09-01
4042 Scale Invariance in fNIRS as a Measurement of Cognitive Load
Zhuang, C.; Meidenbauer, K. L.; Kardan, O.; Stier, A. J.; Choe, K. W.; Cardenas-Iniguez, C.; Huppert, T. J.; Berman, M. G.
10.1101/2021.08.31.458427 — neuroscience — Posted on 2021-09-01
4043 Cell types and clonal relations in the mouse brain revealed by single-cell and spatial transcriptomics
Ratz, M.; von Berlin, L.; Larsson, L.; Martin, M.; Westholm, J. O.; La Manno, G.; Lundeberg, J.; Frisen, J.
10.1101/2021.08.31.458418 — neuroscience — Posted on 2021-09-01
4045 DNA as a Recyclable Natural Polymer
Liu, W.; Giaveri, S.; Ortiz, D.; Stellacci, F.
10.1101/2021.08.31.458327 — biochemistry — Posted on 2021-09-01
4046 Remdesivir-Ivermectin combination displays synergistic interaction with improved in vitro antiviral activity against SARS-CoV-2
Jeffreys, L.; Pennington, S. H.; Duggan, J.; Caygill, C. H.; Lopeman, R. C.; Breen, A.; Jinks, J.; Ardrey, A.; Donnellan, S.; Patterson, E. I.; Hughes, G. I.; Hong, W. D.; O'Neill, P. M.; Aljayyoussi, G.; Owen, A.; Ward, S. A.; Biagini, G. A.
10.1101/2020.12.23.424232 — microbiology — Posted on 2021-09-01
4047 COVID-eVax, an electroporated plasmid DNA vaccine candidate encoding the SARS-CoV-2 Receptor Binding Domain, elicits protective immune responses in animal models of COVID-19
Conforti, A.; Marra, E.; Palombo, F.; Roscilli, G.; Rava, M.; Fumagalli, V.; Muzi, A.; Maffei, M.; Luberto, L.; Lione, L.; Salvatori, E.; Compagnone, M.; Pinto, E.; Pavoni, E.; Bucci, F.; Vitagliano, G.; Stoppoloni, D.; Pacello, M. L.; Cappelletti, M.; Ferrara, F. F.; D'Acunto, E.; Chiarini, V.; Arriga, R.; Nyska, A.; Di Lucia, P.; Marotta, D.; Bono, E.; Giustini, L.; Sala, E.; Perucchini, C.; Paterson, J.; Ryan, K. A.; Challis, A.; Matusali, G.; Colavita, F.; Caselli, G.; Criscuolo, E.; Clementi, N. A.; Mancini, N.; Gross, R.; Siedel, A.; Wettstein, L.; Munch, J.; Donnici, L.; Conti, M.; De F
10.1101/2021.06.14.448343 — immunology — Posted on 2021-09-01
4049 The genome trilogy of Anopheles stephensi, an urban malaria vector, reveals structure of a locus associated with adaptation to environmental heterogeneity
Thakare, A.; Ghosh, C.; Alalamath, T.; Kumar, N.; Narang, H.; Whadgar, S.; Paul, K.; Shrotri, S.; Kumar, S.; M, S.; Rao, R.; Chakraborty, M.; Choudhary, B.; Ghosh, S. K.; Subramani, S.; Swain, S.; Srinivasan, S.
10.1101/2021.08.25.457468 — genomics — Posted on 2021-09-01
4051 Chronic Benzene Exposure Aggravates Pressure Overload-Induced Cardiac Dysfunction
Zelko, I. N.; Dassanayaka, S.; Malovichko, M. V.; Howard, C. M.; Garrett, L. F.; Shizuka, U.; Brittain, K. R.; Conklin, D. J.; Jones, S. P.; Srivastava, S.
10.1101/2021.08.31.458367 — pharmacology and toxicology — Posted on 2021-09-01
4052 Amino acid transporter SLC38A5 regulates developmental and pathological retinal angiogenesis
Wang, Z.; Yemanyi, F.; Huang, S.; Liu, C.-H.; Britton, W. R.; Cho, S. S.; Blomfield, A. K.; Tomita, Y.; Fu, Z.; Ma, J.-x.; Li, W.-h.; Chen, J.
10.1101/2021.09.01.458523 — developmental biology — Posted on 2021-09-01
4054 VaxArray Immunoassay for the Multiplexed Quantification of Poliovirus D-Antigen
Dawson, E. D.; Taylor, A. W.; Johnson, J. E.; Hu, T.; McCormick, C.; Thomas, K. N.; Gao, R. Y.; Wahid, R.; Mahmood, K.; Rowlen, K. L.
10.1101/2021.08.30.458257 — immunology — Posted on 2021-09-01
4055 Age differences in aperiodic neural activity measured with resting EEG
Merkin, A.; Sghirripa, S.; Graetz, L.; Smith, A. E.; Hordacre, B.; Harris, R.; Pitcher, J.; Semmler, J.; Rogasch, N. C.; Goldsworthy, M.
10.1101/2021.08.31.458328 — neuroscience — Posted on 2021-09-01
4058 Sequential Transmission of Task-Relevant Information in Cortical Neuronal Networks
Francis, N.; Mukherjee, S.; Kocillari, L.; Panzeri, S.; Babadi, B.; Kanold, P. O.
10.1101/2021.08.31.458395 — neuroscience — Posted on 2021-09-01
4063 Effect of Vinyl Chloride Exposure on Cardiometabolic Toxicity
Zelko, I. N.; Taylor, B. S.; Das, T. P.; Watson, W. H.; Sithu, I. D.; Wahlang, B.; Malovichko, M. V.; Cave, M. C.; Srivastava, S.
10.1101/2021.08.31.458366 — pharmacology and toxicology — Posted on 2021-09-01
4064 Dominating Lengthscales of Zebrafish Collective Behaviour
Yang, Y.; Turci, F.; Kague, E.; Hammond, C. L.; Russo, J.; Royall, C. P.
10.1101/2021.09.01.458490 — animal behavior and cognition — Posted on 2021-09-01
4065 Efficient ancestry and mutation simulation with msprime 1.0
Baumdicker, F.; Bisschop, G.; Goldstein, D.; Gower, G.; Ragsdale, A. P.; Tsambos, G.; Zhu, S.; Eldon, B.; Ellerman, C. E.; Galloway, J. G.; Gladstein, A. L.; Gorjanc, G.; Guo, B.; Jeffery, B.; Kretzschmar, W. W.; Lohse, K.; Matschiner, M.; Nelson, D.; Pope, N. S.; Quinto-Cortes, C. D.; Rodrigues, M. F.; Saunack, K.; Sellinger, T.; Thornton, K.; van Kemenade, H.; Wohns, A. W.; Wong, Y.; Gravel, S.; Kern, A. D.; Koskela, J.; Ralph, P. L.; Kelleher, J.
10.1101/2021.08.31.457499 — genetics — Posted on 2021-09-01
4067 Population assessment and habitat associations of the Visayan Hornbill Penelopides panini in Northwest Panay, Philippines
Mynott, H. I.; Lee, D. C.; Santillan, R. A.; Schwarz, C. J.; Tacud, B.; Fernandez, A. D.; Kerhoas, D.
10.1101/2021.08.31.458333 — ecology — Posted on 2021-09-01
4069 Programming isotype specific plasma cell differentiation
Higgins, B. W.; Shuparski, A. G.; Miller, K. B.; Robinson, A. M.; McHeyzer-Williams, L. J.; McHeyzer-Williams, M. G.
10.1101/2021.08.31.458458 — immunology — Posted on 2021-09-01
4072 Disentangling the flow of signals between populations of neurons
Gokcen, E.; Jasper, A. I.; Semedo, J. D.; Zandvakili, A.; Kohn, A.; Machens, C. K.; Yu, B. M.
10.1101/2021.08.30.458230 — neuroscience — Posted on 2021-09-01
4073 SMN controls neuromuscular junction integrity through U7 snRNP
Tisdale, S.; Van Alstyne, M.; Simon, C. M.; Mentis, G. Z.; Pellizzoni, L.
10.1101/2021.08.31.458410 — neuroscience — Posted on 2021-09-01
4076 An Arabidopsis root phloem pole cell atlas reveals PINEAPPLE genes as transitioners to autotrophy
Otero, S.; Sevilem, I.; Roszak, P.; Lu, Y.; Di Vittori, V.; Bourdon, M.; Kalmbach, L.; Blob, B.; Heo, J.-o.; Peruzzo, F.; Laux, T.; Fernie, A. R.; Tavares, H.; Helariutta, Y.
10.1101/2021.08.31.458411 — plant biology — Posted on 2021-09-01
4077 Tomato leaves under stress: A comparison of stress response to mild abiotic stress between a cultivated and a wild tomato species
Reimer, J. J.; Thiele, B.; Biermann, R. T.; Junker-Frohn, L. V.; Wiese-Klinkenberg, A.; Usadel, B. J.; Wormit, A.
10.1101/2021.08.31.458379 — plant biology — Posted on 2021-09-01
4083 Free energy and stacking of eumelaninnanoaggregates
Soltani, S.; Sowlati-Hashjin, S.; Tetsassi, C.; Karttunen, M.
10.1101/2021.08.31.458381 — biophysics — Posted on 2021-09-01
4087 Temporal and sex-dependent gene expression patterns in a renal ischemia-reperfusion injury and recovery pig model
Nemours, S.; Castro, L.; Ribatallada-Soriano, D.; Semidey, M. E.; Aranda, M.; Ferrer, M.; Sanchez, A.; Morote, J.; Cantero, G.; Meseguer, A.
10.1101/2021.09.01.458480 — genomics — Posted on 2021-09-01
4088 Non-additive QTL mapping of lactation traits in 124,000 sequence-imputed cattle reveals novel recessive loci
Reynolds, E. G.; Lopdell, T. J.; Wang, Y.; Tiplady, K.; Harland, C.; Johnson, T.; Neeley, C.; Carnie, K.; Sherlock, R.; Couldrey, C.; Davis, S.; Harris, B.; Spelman, R.; Garrick, D.; Littlejohn, M.
10.1101/2021.08.30.457863 — genetics — Posted on 2021-09-01
4089 Sexual morph specialisation in a trioecious nematode balances opposing selective forces.
Adams, S.; Pathak, P.; Kittelmann, M.; Jones, A. R. C.; Mallon, E. B.; Pires da Silva, A.
10.1101/2021.08.31.458370 — evolutionary biology — Posted on 2021-09-01
4095 The unfolded protein response triggers the ancestral immune deficiency pathway
Sidak-Loftis, L. C.; Rosche, K. L.; Pence, N.; Ujczo, J. K.; Hurtado, J.; Fisk, E. A.; Noh, S. M.; Peters, J. W.; Shaw, D. K.
10.1101/2021.08.31.458430 — immunology — Posted on 2021-09-01
4096 A comprehensive neural simulation of slow-wave sleep and highly responsive wakefulness dynamics
Goldman, J. S.; Kusch, L.; Yalcinkaya, B. H.; Depannemaecker, D.; Nghiem, T.-A. E.; Jirsa, V.; Destexhe, A.
10.1101/2021.08.31.458365 — neuroscience — Posted on 2021-09-01
4098 Coordinated drift of receptive fields during noisy representation learning
Qin, S.; Farashahi, S.; Lipshutz, D.; Sengupta, A. M.; Chklovskii, D. B.; Pehlevan, C.
10.1101/2021.08.30.458264 — neuroscience — Posted on 2021-09-01
4099 Stimulus degradation impairs performance in a rodent continuous performance test
DeBrosse, A. C.; Li, Y.; Wiseman, R.; Ross, R.; Garrison, S.; Hallock, H. L.; Barrow, J. C.; Martinowich, K.; Carr, G. V.
10.1101/2021.08.31.458320 — neuroscience — Posted on 2021-09-01
4100 Multiple Sclerosis Patients have an Altered Gut Mycobiome and Increased Fungal to Bacterial Richness Running Title: RRMS Patients have Gut Fungal Dysbiosis
Yadav, M.; Ali, S.; Shrode, R. L.; Shahi, S. K.; Jensen, S. N.; Hoang, J.; Cassidy, S.; Olalde, H.; Guseva, N.; Paullus, M.; Cherwin, C.; Wang, K.; Cho, T.; Kamholz, J.; Mangalam, A. K.
10.1101/2021.08.30.458212 — neuroscience — Posted on 2021-09-01
4101 Biomarkers Of Cardiovascular Toxicity Of Benzene Inhalation In Mice
Malovichko, M. V.; Abplanalp, W. T.; McFall, S. A.; Taylor, B. S.; Wickramasinghe, N. S.; Sithu, I. D.; Zelko, I. N.; Uchida, S.; Sutaria, S. R.; Nantz, M. H.; Bhatnagar, A.; Conklin, D. J.; O'Toole, T. E.; Srivastava, S.
10.1101/2021.08.31.458364 — pharmacology and toxicology — Posted on 2021-09-01
4102 The non-steroidal anti-inflammatory drug nimesulide kills Gyps vultures at concentrations found in the muscle of treated cattle.
Galligan, T. H.; Green, R. E.; Wolter, K.; Taggart, M. A.; Duncan, N.; Mallord, J. W.; Alderson, D.; Li, Y.; Naidoo, V.
10.1101/2021.08.31.457916 — pharmacology and toxicology — Posted on 2021-09-01
4103 Impact of charge patches on tumor disposition and biodistribution of therapeutic antibodies
Stueber, J. C.; Miladinovic, S. M.; Poeschinger, T.; Zimmermann, T.; Villenave, R.; Eigenmann, M. J.; Kraft, T. E.; Shah, D. K.; Kettenberger, H.; Richter, W. F.
10.1101/2021.09.01.458024 — cancer biology — Posted on 2021-09-01
4104 Breast tumor IGF-1R regulates cell adhesion and metastasis: Alignment of mouse single cell and human breast cancer transcriptomics
Obr, A. E.; Chang, Y.-J.; Ciliento, V.; Lemenze, A.; Maingrette, K.; Bulatowicz, J. J.; Shang, Q.; Gallagher, E.; LeRoith, D.; Wood, T. L.
10.1101/2021.08.31.458283 — cancer biology — Posted on 2021-09-01
4105 JAMMIT Analysis Defines 2 Semi-Independent Immune Processes Common to 29 Solid Tumors
Zitello, E.; Vo, M.; Bowler, S.; Chen, S.; Wenska, T.; Khadka, V.; Hoffmann, P.; Okimoto, G.; Deng, Y.
10.1101/2021.08.31.458339 — cancer biology — Posted on 2021-09-01
4106 Co-aggregation and secondary nucleation in the life cycle of human prolactin/galanin functional amyloids
Chatterjee, D.; Jacob, R. S.; Ray, S.; Navalkar, A.; Singh, N.; Sengupta, S.; Gadhe, L.; Kadu, P.; Datta, D.; Paul, A.; Pindi, C.; Kumar, S.; Singru, P. S.; Senapati, S. K.; Maji, S. K.
10.1101/2021.08.31.458467 — biophysics — Posted on 2021-09-01
4111 Imaging erythrocyte sedimentation in whole blood
Darras, A.; Breunig, H. G.; John, T.; Zhao, R.; Koch, J.; Kummerow, C.; König, C.; Wagner, C.; Kaestner, L.
10.1101/2021.08.31.458375 — biophysics — Posted on 2021-09-01
4114 Cryo-ET of HIV reveals Env positioning on Gag lattice and structural variation among Env trimers
Mangala Prasad, V.; Leaman, D. P.; Lovendahl, K. N.; Benhaim, M. A.; Hodge, E. A.; Zwick, M. B.; Lee, K. K.
10.1101/2021.08.31.458345 — biophysics — Posted on 2021-09-01
4115 De Novo Prediction of RNA 3D Structures with Deep Learning
Ramakers, J.; Blum, C. F.; König, S.; Harmeling, S.; Kollmann, M.
10.1101/2021.08.30.458226 — bioinformatics — Posted on 2021-09-01
4118 Closed-loop optimization of transcranial magnetic stimulation with electroencephalography feedback
Tervo, A. E.; Nieminen, J. O.; Lioumis, P.; Metsomaa, J.; Souza, V. H.; Sinisalo, H.; Stenroos, M.; Sarvas, J.; Ilmoniemi, R. J.
10.1101/2021.08.31.458148 — bioengineering — Posted on 2021-09-01
4123 Systematic discovery of gene fusions in pediatric cancer by integrating RNA-seq and WGS
van Belzen, I. A. E. M.; Cai, C.; Tuil, M. v.; Badloe, S.; Strengman, E.; Janse, A.; Verwiel, E. T.; van der Leest, D. F. M.; Kester, L. A.; Molenaar, J. J.; Meijerink, J.; Drost, J.; Peng, W. C.; Kerstens, H. H. D.; Tops, B. B. J.; Holstege, F. C. P.; Kemmeren, P.; Hehir-Kwa, J. Y.
10.1101/2021.08.31.458342 — genomics — Posted on 2021-09-01
4125 Genome-wide identification of sexual-reproduction genes in fission yeast via transposon-insertion sequencing
Billmyre, R. B.; Eickbush, M. T.; Craig, C. J.; Lange, J. J.; Wood, C.; Helston, R. M.; Zanders, S. E.
10.1101/2021.08.31.458362 — genetics — Posted on 2021-09-01
4133 Redox-mediated inactivation of the transcriptional repressor C3600 makes uropathogenic Escherichia coli exquisitely resistant to reactive chlorine species
Sultana, S.; LeDoux, K.; Crompton, M. E.; Jankiewicz, O.; Morales, G. H.; Johnson, C.; Horbach, E.; Hoffmann, K. P.; KR, P.; Shah, R.; Anderson, G. M.; Mortimer, N. T.; Schmitz, J. E.; Hadjifrangiskou, M.; Foti, A.; Dahl, J.-U.
10.1101/2021.08.31.458474 — microbiology — Posted on 2021-09-01
4134 HIV-1 Induction of Tolerogenic DCs is Mediated by Cellular Interaction with Suppressive T Cells
Svanberg, C.; Nystrom, S.; Govender, M.; Bhattacharya, P.; Karlhans, C. F.; Ellegard, R.; Shankar, E. M.; Larsson, M.
10.1101/2021.09.01.458353 — immunology — Posted on 2021-09-01
4139 Axonal length determines distinct homeostatic phenotypes in human iPSC derived motor neurons on a bioengineered platform
Hagemann, C.; Moreno Gonzalez, C.; Guetta, L.; Tyzak, G.; Chiappini, C.; Legati, A.; Patani, R.; Serio, A.
10.1101/2021.08.30.458271 — neuroscience — Posted on 2021-09-01
4141 NEURON-SPECIFIC CHROMOSOMAL MEGADOMAIN ORGANIZATION IS ADAPTIVE TO RECENT RETROTRANSPOSON EXPANSIONS
Chandrasekaran, S.; Espeso-Gil, S.; Loh, Y.-H. E.; Javidfar, B.; Kassim, B.; Dong, Y.; Zhu, Y.; Bicks, L. K.; Rajarajan, P.; Peter, C. J.; Agullo-Pascual, E.; Iskhakova, M.; Estill, M.; Shen, L.; Jiang, Y.; Akbarian, S.
10.1101/2021.08.30.458289 — neuroscience — Posted on 2021-09-01
4145 Correlations between metabolites in the synovial fluid and serum: a mouse injury study
Wallace, C. W.; Hislop, B. D.; Hahn, A. K.; Erdogan, A. E.; Brahmachary, P. P.; June, R. K.
10.1101/2021.08.30.458234 — pathology — Posted on 2021-09-01
4146 Patient derived organoids reveal that PI3K/AKT signaling is an escape pathway for radioresistance and a target for therapy in rectal cancer.
Wanigasooriya, K.; Barros-Silva, J. D.; Tee, L.; Elasrag, M. E.; Stodolna, A.; Pickles, O.; Stockton, J. D.; Bryer, C.; Hoare, R.; Whalley, C. M.; Tyler, R.; Sillo, T.; Yau, C.; Ismail, T.; Beggs, A. D.
10.1101/2021.08.31.458326 — cancer biology — Posted on 2021-09-01
4149 Bone-Specific Enhancement of Antibody Therapy for Breast Cancer Metastasis to Bone
Tian, Z.; Yu, C.; Zhang, W.; Wu, K.-l.; Gupta, R.; Xu, Z.; Wu, L.; Chen, Y.; Zhang, X.; Xiao, H.
10.1101/2021.08.31.457412 — bioengineering — Posted on 2021-09-01
4150 Microstructured hydrogels to guide self-assembly and function of lung alveolospheres
Loebel, C.; Weiner, A.; Katzen, J.; Morley, M.; Bala, V.; Cardenas-Diaz, F.; Davidson, M.; Shiraishi, K.; Basil, M.; Ochs, M.; Beers, M.; Morrisey, E.; Vaughan, A. E.; Burdick, J.
10.1101/2021.08.30.457534 — bioengineering — Posted on 2021-09-01
4152 Dicer-to-Argonaute switch controls biogenesis of oncogenic miRNA
Winchester, L.; van Bijsterveldt, L.; Dhawan, A.; Wigfield, S.; Triantafyllidis, C.; Haider, S.; McIntyre, A.; Humphrey, T.; Harris, A.; Buffa, F. M.
10.1101/2021.08.30.458145 — genomics — Posted on 2021-09-01
4153 Interoception of breathing and its relationship with anxiety
Harrison, O. K.; Koechli, L.; Marino, S.; Luechinger, R.; Hennel, F.; Brand, K.; Hess, A. J.; Fraessle, S. K.; Iglesias, S.; Vinckier, F.; Petzschner, F. H.; Harrison, S. J.; Stephan, K. E.
10.1101/2021.03.24.436881 — neuroscience — Posted on 2021-09-01
4154 Induced Cognitive Impairments Reversed by Grafts of Neural Precursors: a Longitudinal Study in a Macaque Model of Parkinson's Disease
Wianny, F.; Dzahini, K.; Fifel, K.; Wilson, C. R. E.; Bernat, A.; Dolmazon, V.; Misery, P.; Lamy, C.; Cooper, H. M.; Procyk, E.; Kennedy, H.; Savatier, P.; Dehay, C.; Vezoli, J.
10.1101/2020.12.17.423293 — neuroscience — Posted on 2021-09-01
4155 Population differences in the length and early-life dynamics of telomeres among European pied flycatchers
Karkkainen, T.; Laaksonen, T.; Burgess, M.; Cantarero, A.; Martinez-Padilla, J.; Potti, J.; Moreno, J.; Thomson, R. L.; Tilgar, V.; STIER, A.
10.1101/2021.03.16.435615 — zoology — Posted on 2021-09-01
4157 Integrative Omics Reveals Subtle Molecular Perturbations Following Ischemic Conditioning in a Porcine Kidney Transplant Model
O'Brien, D. P.; Thorne, A. M.; Huang, H.; Pappalardo, E.; Yao, X.; Soendergaard Thyrrestrup, P.; Ravlo, K. R.; Secher, N. S.; Norregaard, R. N.; Ploeg, R. J.; Jespersen, B.; Kessler, B. M.
10.1101/2021.04.23.441109 — physiology — Posted on 2021-09-01
4161 A Cytosolic Reductase Pathway is Required for Complete N-Glycosylation of an STT3B-Dependent Acceptor Site.
van Lith, M.; Pringle, M. A.; Fleming, B.; Gaeta, G.; Im, J.; Gilmore, J. R.; Bulleid, N. J.
10.1101/2021.08.31.458373 — cell biology — Posted on 2021-09-01
4162 ExBoX: a simple Boolean exclusion strategy to drive expression in neurons
Ubina, T.; Vahedi-Hunter, T.; Gupta, A.; Wong, W.; Agnew-Svoboda, W.; Santhakumar, V.; Riccomagno, M. M.
10.1101/2020.07.28.224691 — neuroscience — Posted on 2021-09-01
4163 Robust designation of meiotic crossover sites by CDK-2 through phosphorylation of the MutSγ complex
Haversat, J.; Woglar, A.; Klatt, K.; Akerib, C. C.; Roberts, V.; Salazar, C. C.; Chen, S.-Y.; Arur, S.; Villeneuve, A. M.; Kim, Y.
10.1101/2021.08.31.458431 — cell biology — Posted on 2021-09-01
4164 Exploring the kinetic selectivity of drugs targeting the β1-adrenoceptor
Sykes, D. A.; Jimenez Roses, M.; Reilly, J.; Fairhurst, R. A.; Charlton, S. J.; Veprintsev, D. B.
10.1101/2021.08.31.458064 — pharmacology and toxicology — Posted on 2021-09-01
4165 H+/K+ ion pump enhances cytoskeletal polarity to drive gastrulation in sea urchin embryo
Watanabe, K.; Yasui, Y.; Kurose, Y.; Fujii, M.; Yamamoto, T.; Sakamoto, N.; Awazu, A.
10.1101/2021.08.31.458310 — developmental biology — Posted on 2021-09-01
4167 Multimodal characterization of the murine neurovascular niche using a novel microvascular isolation protocol
Bjornholm, K. D.; Vanlandewijck, M.; Del Gaudio, F.; Lendahl, U.; Nilsson, P.; Karlström, H.; Betsholtz, C.
10.1101/2021.08.31.458349 — cell biology — Posted on 2021-09-01