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Archive, 2024-09

2 Impact of early-life respiratory syncytial virus infection on cell type-specific airway DNA methylation
McKennan, C.; Newcomb, D.; Berdnikovs, S.; Gebretsadik, T.; Ma, S.; Bacharier, L. B.; Seibold, M.; Anderson, L. J.; Gern, J.; Ober, C.; Hartert, T.
10.1101/2024.09.29.615688 — genomics — Posted on 2024-09-30
6 Band-selective IR PRESS for brain tumor spectroscopy allows robust detection of lactate
Kishimoto, S.; Kim, O.; Munasinghe, J.; Yasunori, O.; Yamashita, K.; Yamamoto, K.; Linehan, W. M.; Wu, J.; Krishna, M. C.; Brender, J. R.
10.1101/2024.09.30.615849 — biochemistry — Posted on 2024-09-30
7 The Plasmodium falciparum NCR1 membrane protein is a novel antimalarial target that exports cholesterol to maintain membrane homeostasis
Zhang, Z.; Lyu, M.; Han, X.; Bandara, S.; Cui, M.; Istvan, E. S.; Geng, X.; Tringides, M.; Gregor, W.; Miyagi, M.; Oberstaller, J.; Adams, J. H.; Zhang, Y.; Nieman, M.; von Lintig, J.; Goldberg, D.; Yu, E. W.
10.1101/2024.09.30.615907 — biochemistry — Posted on 2024-09-30
9 Covalent Stabilization of Collagen Mimetic Triple Helices and Assemblies by Dopa Crosslinking
Cole, C. C.; Pogostin, B. H.; Vardanyan, V.; Cahue, K. A.; Bui, T. H.; Farsheed, A. C.; Swain, J. W. R.; Makhoul, J. T.; Dubackic, M.; Holmqvist, P.; Olsson, U.; Kolomeisky, A.; McHugh, K.; Hartgerink, J. D.
10.1101/2024.09.30.615841 — biochemistry — Posted on 2024-09-30
10 An ALPK3 truncation variant causing autosomal dominant hypertrophic cardiomyopathy is partially rescued by mavacamten
Leinhos, L.; Robinson, P.; Poloni, G.; Broadway-Stringer, S.; Beglov, J.; Lokman, A. B.; Douglas, G.; Nuthay, S.; Fonseka, O.; Schmid, M.; Singer, E.; Hooper, C.; Thomson, K.; Bagnall, R. D.; Ingles, J.; Semsarian, C.; Ormondroyd, E.; Toepfer, C. N.; Davies, B.; Redwood, C.; Watkins, H.; Gehmlich, K.
10.1101/2024.09.30.615779 — genetics — Posted on 2024-09-30
11 Ribozyme-based biosensor for imaging gene expression in plants
Liu, Y.; Rajput, R.; Islam, T.; Valle, I. D.; Yao, T.; Agarwal, R.; Boone, B. A.; Eckert, C. A.; Abraham, P. E.; Chen, J.-G.; Tuskan, G. A.; Yang, X.
10.1101/2024.09.30.615876 — synthetic biology — Posted on 2024-09-30
13 Glycogen phosphorylase from the methanogenic archaeon Methanococcus maripaludis: Unique regulatory properties of a pyridoxal 5'-phosphate independent phosphorylase
Gonzalez-Ordenes, F.; Herrera-Soto, N.; Hernandez-Cabello, L.; Bustamante, C.; Vallejos-Baccelliere, G.; Castro-Fernandez, V.; Guixe, V.
10.1101/2024.09.29.615707 — biochemistry — Posted on 2024-09-30
14 Identification and determination of the urinary metabolite of iodotyrosine in vivo
Ji, C. X.; Zonias, D.; Djumaeva, N.; Cheng, R.; Salim, K.; Alikhani, P.; Oyelade, T.; Moore, K.; Moreno, J. C.; Mani, A. R.
10.1101/2024.09.30.615905 — biochemistry — Posted on 2024-09-30
15 High-throughput diversification of protein-ligand surfaces to discover chemical inducers of proximity
Shaum, J. B.; Steen, E. A.; Munoz i Ordono, M.; Wenge, D. V.; Cheong, H.; Hunkeler, M.; Bilotta, E. M.; Rutter, Z.; Barta, P. A.; Milosevich, N.; Hargis, L. M.; Janowski, J.; Bishop, T. R.; Carter, T. R.; da Camara, B.; Hinterndorfer, M.; Dada, L.; He, W.-J.; Offensperger, F.; Furihata, H.; Schweber, S. R.; Hatton, C.; Wen, Y.; Cravatt, B. F.; Engle, K. M.; Melillo, B.; Kitamura, S.; Ciulli, A.; Armstrong, S. A.; Fischer, E. S.; Winter, G. E.; Erb, M. A.
10.1101/2024.09.30.615685 — biochemistry — Posted on 2024-09-30
16 MARLOWE: Taxonomic Characterization of Unknown Samples for Forensics Using De Novo Peptide Identification
Jenson, S. C.; Chu, F.; Barente, A. S.; Crockett, D. L.; Lamar, N. C.; Merkley, E. D.; Jarman, K. H.
10.1101/2024.09.30.615220 — biochemistry — Posted on 2024-09-30
18 An all-in-one AAV vector for cardiac-specific gene silencing by an adenine base editor
Liu, Z.; Yang, L.; Yang, Y.; Li, J.; Chen, Z.; Guo, C.; Guo, Q.; Li, Q.; Sun, Y.; Zhao, D.; Hu, X.; Gao, F.; Guo, Y.
10.1101/2024.09.30.615742 — molecular biology — Posted on 2024-09-30
19 Impact of biosolids amendment on the soil resistome and microbiome - a greenhouse study
Ste.Marie, J. P.; Mays, C.; Guo, B.; Radniecki, T. S.; Waite-Cusic, J.; Navab-Daneshmand, T.
10.1101/2024.09.30.615847 — molecular biology — Posted on 2024-09-30
21 A host-directed adjuvant resuscitates and sensitizes intracellular bacterial persisters to antibiotics
Lu, K.-Y.; Yang, X.; Eldridge, M. J. G.; Wagner, N. J.; Hardy, B.; Axtman, M.; Rowe, S. E.; Wang, X.; Helaine, S.; Pearce, K. H.; Fowler, V. G.; Conlon, B. P.
10.1101/2024.09.30.615828 — microbiology — Posted on 2024-09-30
25 Typhi Mykrobe: fast and accurate lineage identification and antimicrobial resistance genotyping directly from sequence reads for the typhoid fever agent Salmonella Typhi
Ingle, D. J.; Hawkey, J. J.; Hunt, M.; Iqbal, Z.; Keane, J.; Afolayan, A. O.; Ahmed, N.; Andleeb, S.; Ashton, P. M.; Bogoch, I. I.; Carey, M. E.; Chattaway, M. A.; Crump, J. A.; Guevara, P. D.; Howden, B.; Izumiya, H.; Jacob, J. J.; Judd, L. M.; Kapil, A.; Keddy, K. H.; Kim, J.; Levine, M. M.; Morita, M.; Nair, S.; Octavia, S.; Okeke, I. N.; Osadebamwen, P.; Rahman, S. I. A.; Rokney, A.; Rasko, D.; Shamanna, V.; Sikorski, M. J.; Smith, A. M.; Sunmonu, G. T.; Tagg, K. A.; Wick, R. R.; Dyson, Z. A.; Holt, K.; Global Typhoid Genomics Consortium,
10.1101/2024.09.30.613582 — microbiology — Posted on 2024-09-30
26 Clostridioides difficile in Equidae necropsied in Normandie, France from 2019 to 2021: common carriage of toxigenic strains and virulence of emerging ribotype 017
Petry, S.; Tapprest, J.; Maillard, K.; Barbut, F.; DUQUESNE, F.; Kozak, S.; FOUCHER, N.; BERNEZ-ROMAND, M.; Bridoux, L.; Poquet, I.
10.1101/2024.09.30.615820 — microbiology — Posted on 2024-09-30
28 Long-read metagenomics empowers precise tracking of bacterial strains and their genomic changes after fecal microbiota transplantation
Fan, Y.; Ni, M.; Aggarwala, V.; Mead, E. A.; Ksiezarek, M.; Kamm, M. A.; Borody, T.; Paramsothy, S.; Kaakoush, N. O.; Grinspan, A.; Faith, J. J.; Fang, G.
10.1101/2024.09.30.615906 — microbiology — Posted on 2024-09-30
30 Dietary L-3,4-dihydroxyphenylalanine (L-DOPA) augments cuticular melanization in Anopheles mosquitos while reducing their lifespan and malaria parasite burden
Camacho, E.; Dong, Y.; Chrissian, C.; Cordero, R. J.; Saraiva, R. G.; Anglero-Rodriguez, Y.; Smith, D. F. Q.; Jacobs, E.; Hartshorn, I.; Patino-Medina, J. A.; DePasquale, M.; Dziedzic, A.; Jedlicka, A.; Smith, B.; Mlambo, G.; Tripathi, A.; Broderick, N. A.; Stark, R. E.; Dimopoulos, G.; Casadevall, A.
10.1101/2024.09.30.615839 — microbiology — Posted on 2024-09-30
32 An unprecedented small RNA-riboswitch interaction controls expression of a bifunctional pump that is essential for Staphylococcus aureus infection
Gonzalez-Espinoza, G.; Prevost, K.; Hussain, F.; Radin, J. N.; Valle, C. D. V.; Maucotel, J.; Barroso, M. V.; Marteyn, B. S.; Masse, E.; Romby, P.; Kehl-Fie, T. E.; Georg, J.; Lalaouna, D.
10.1101/2024.09.30.615890 — microbiology — Posted on 2024-09-30
34 Improving the visualization of viruses in soil
Parvate, A. D.; Alfaro, T.; McDearis, R. W.; Zimmerman, A.; Hofmockel, K.; Nelson, W. C.; Evans, J. E.
10.1101/2024.09.30.615710 — microbiology — Posted on 2024-09-30
36 A Versatile Light Field Microscopy Platform for Multi-purpose Dynamic Volumetric Bio-imaging
Bai, Y.; Jones, M.; Ojeda, L. S.; Cuala, J.; Cherchia, L.; Georgia, S. K.; White, K. L.; Fraser, S. E.; Truong, T. V.
10.1101/2024.09.30.615205 — bioengineering — Posted on 2024-09-30
37 Quantitative phase imaging with temporal kinetics predicts hematopoietic stem cell diversity
Yogo, T.; Iwmaoto, Y.; Hans Jiro, B.; Kimura, T.; Sugiyama-Finnis, A.; Yokomizo, T.; Suda, T.; Ota, S.; Yamazaki, S.
10.1101/2024.09.29.615639 — cell biology — Posted on 2024-09-30
39 Deciphering the role of the nanoscale clustering of activating and costimulatory antibodies on T cell activation
Le Saux, G.; Nowakowski, P.; Toledo, E.; Tzdaka, S.; Al-Kader Yassin, A.; Naaz, S.; Segal, Y.; Maman, B.; Porgador, A.; Smith, A.-S.; Schvartzman, M.
10.1101/2024.09.28.615509 — immunology — Posted on 2024-09-30
44 Cyclooxygenase-2 disruption predisposes to heart failure with preserved ejection fraction
Ricciotti, E.; Haines, P.; Beerens, M.; Kartoun, U.; Castro, C.; Tang, S. Y.; Ghosh, S.; Das, U.; Lahens, N.; Wang, T.; Griffin, J.; Shaw, S.; Macrae, C.; FitzGerald, G. A.
10.1101/2024.09.28.615616 — pharmacology and toxicology — Posted on 2024-09-30
46 Concentration dependent CsrA regulation of the uxuB transcript leads to development of post-transcriptional BANDPASS Filter
Rojano-Nisimura, A. M.; Simmons, T. R.; Lukasiewicz, A.; Buchser, R.; Ruzek, J. S.; Avila, J. L.; Contreras, L. M.
10.1101/2024.09.28.615595 — bioengineering — Posted on 2024-09-30
49 High-throughput targeted amplicon screening tool for characterizing intrahost diversity in Staphylococcus aureus directly from sample
Furstenau, T. N.; Whealy, R.; Timm, S.; Roberts, A.; Maltinsky, S.; Wells, S.; Drake, K.; Ross, A.; Bolduc, C.; Pearson, T.; Fofanov, V. Y.
10.1101/2024.09.27.615532 — genomics — Posted on 2024-09-30
50 Early hominin arrival in Southeast Asia triggered the evolution of major human malaria vectors
Singh, U. S.; Harbach, R. E.; Hii, J.; Chang, M. S.; Somboon, P.; Prakash, A.; Sarma, D.; Broomfield, B.; Morgan, K.; Albert, S.; Das, A.; Linton, Y.-M.; Carlton, J. M.; Walton, C.
10.1101/2024.09.28.615606 — evolutionary biology — Posted on 2024-09-30
53 Sex differences in colonic inflammation are driven by epithelial-specific expression of estrogen receptor alpha
Pereda, G. A.; Kocinski, A. D.; Broncano, A. V.; McNeer, S. K.; Raymond, M. L.; Ziats, N. P.; Breau, K. A.; Burclaff, J.; Magness, S. T.; Goodman, W. A.
10.1101/2024.09.28.615598 — cell biology — Posted on 2024-09-30
55 In vivo imaging of T-cell coregulator B7-H4 reveals protumor macrophage status in prostate cancer
Kumar, M.; Singh, S. B. S.; Vasyliv, I.; Habte, F. G.; Kalita, M.; Alam, I. S.; Dai, S.-Y.; James, M. L.; Rao, J.; Beziere, N.; Daldrup-Link, H. E.
10.1101/2024.09.28.615608 — immunology — Posted on 2024-09-30
56 Effector T Cells under Hypoxia have an Altered Transcriptome Similar to Tumor-Stressed T Cells Found in Non-Responsive Melanoma Patients
Nagy, M. Z.; Plaza Rojas, L. B.; Boucher, J. C.; Kostenko, E.; Austin, A. L.; Tarhini, A.; Chen, Z.; Du, D.; Ojwang, A. M. E.; Davis, J.; Rejiniak, K. A.; Shaw, T. I.; Guevara, J. A.
10.1101/2024.09.27.615474 — immunology — Posted on 2024-09-30
59 A rich conformational palette underlies human CaV2.1-channel availability
Wang, K.; Nilsson, M.; Angelini, M.; Olcese, R.; Elinder, F.; Pantazis, A.
10.1101/2024.09.27.615501 — neuroscience — Posted on 2024-09-30
60 Levodopa impairs lysosomal function in sensory neurons in vitro
Olaoye, O. J.; Aksoy, A. E.; Hyytiäinen, S. V.; Narits, A. A.; Hickey, M. A.
10.1101/2024.09.29.614220 — neuroscience — Posted on 2024-09-30
61 Temporal Dynamics of Nucleus Accumbens Neurons in Male Mice During Reward Seeking
Schall, T. A.; Li, K.-l.; Qi, X.; Lee, B. T.; Wright, W. J.; Alpaugh, E. E.; Zhao, R. J.; Liu, J.; Li, Q.; Zeng, B.; Wang, L.; Huang, Y. H.; Schlueter, O.; Nestler, E. J.; Nieh, E. H.; Dong, Y.
10.1101/2024.09.27.615291 — neuroscience — Posted on 2024-09-30
65 Effects of systemic oxytocin and beta-3 receptor agonist (CL 316243) treatment on body weight and adiposity in male diet-induced obese rats
Slattery, J. D.; Rambousek, J. R.; Tsui, E.; Honeycutt, M. K.; Goldberg, M.; Graham, J. L.; Wietecha, T. A.; Wolden-Hanson, T.; O'Brien, K. D.; Havel, P. J.; Blevins, J. E.
10.1101/2024.09.27.615550 — neuroscience — Posted on 2024-09-30
66 Evaluation of scalp-based targeting methods of DLPFC for TMS therapy: EEG cap F3, Beam F3, CPC F3, and adjusted Beam F3
Jiang, Y.; Chen, Y.; Wei, L.; Liu, F.; Zheng, Z.; Zhang, Z.; Li, Z.; Tang, Y.; Wang, J.; Xie, Q.; Niu, C. M.; Zhu, C.
10.1101/2024.09.28.615621 — neuroscience — Posted on 2024-09-30
67 Test-Retest Reliability and repeatability of Behavioral and Electrophysiological Markers in an Eriksen Flanker Task
Bogdanov, M.; Scott, J. N.; Esfand, S. M.; Boyle, B. W.; Lees, T.; Li, M.; Woronko, S. E.; Linton, S. R.; Miller, C.; Li, S.; Bolton, P.; Meisner, R. C.; Pizzagalli, D. A.
10.1101/2024.09.28.615624 — neuroscience — Posted on 2024-09-30
69 Engineered Feedback Employing Natural Hypoxia-Responsive Factors Enhances Synthetic Hypoxia Biosensors
Dreyer, K. S.; Donahue, P. S.; Boucher, J. D.; Chambers, K. M.; Ornelas, M. Y.; Edelstein, H. I.; Leibowitz, B. D.; Zhu, K. J.; Dray, K. E.; Muldoon, J. J.; Leonard, J. N.
10.1101/2024.09.28.615614 — synthetic biology — Posted on 2024-09-30
71 The dynamics of wild Vitis species in response to climate change facilitate the breeding of grapevine and its rootstocks with climate resilience
Zhang, M.; Xu, X.; Zhang Tianhao, T.-H.; Liu, Z.; Wang, X.; Shi, X.; Peng, W.; Wang, X.; Chen, Z.; Zhao, R.; Wang, W.; Jin, Z.; Zhou, Y.; Ma, Z.
10.1101/2024.09.28.615618 — plant biology — Posted on 2024-09-30
74 Latent-TGF-β has a domain swapped architecture
Jin, M.; Seed, R.; Shing, T.; Cheng, Y.; Nishimura, S.
10.1101/2024.09.27.615443 — biophysics — Posted on 2024-09-30
76 Cryo-EM visualizes multiple steps of dynein activation pathway
Kendrick, A.; Nguyen, K.; MA, W.; Karasmanis, E.; Amaro, R. E.; Reck-Peterson, S.; Leschziner, A.
10.1101/2024.09.28.615567 — biophysics — Posted on 2024-09-30
78 RapA opens the RNA polymerase clamp to disrupt post-termination complexes and prevent cytotoxic R-loop formation
Brewer, J. J.; Inlow, K.; Mooney, R. A.; Bosch, B.; Olinares, P. D. B.; Marcelino, L. P.; Chait, B. T.; Landick, R.; Gelles, J.; Campbell, E. A.; Darst, S. A.
10.1101/2024.09.28.614012 — biophysics — Posted on 2024-09-30
80 Real-time affinity measurements of proteins synthesized in cell-free lysate using fluorescence correlation spectroscopy
Liu, C.; Hoang-Phou, S.; Ye, C.; Laurence, E. J.; Laurence, M. J.; Fong, E. J.; Hammond, N. M.; Vannest, B. D.; Watkins, N. N.; Laurence, T. A.; Coleman, M. A.
10.1101/2024.09.28.615564 — biophysics — Posted on 2024-09-30
85 Distinct gene regulatory networks govern hematopoietic and leukemia stem cells
Zhang, B.; Murison, A.; Varesi, A.; Takayama, N.; Jin, L.; Mbong, N.; Schoof, E. M.; Xie, S.; Mitchell, A.; Etchin, J.; Look, A. T.; Lupien, M.; Minden, M. D.; Wang, J. C. Y.; Zandstra, P. W.; Wagenblast, E.; Dick, J. E.; Ng, S. W. K.
10.1101/2024.09.28.614980 — bioinformatics — Posted on 2024-09-30
88 Refined Myocardium Segmentation from CT Using a Hybrid-Fusion Transformer
Qin, S.; Xing, F.; Cho, J.; Park, J.; Liu, X.; Rouhollahi, A.; Bou Farhat, E. J.; Javadikasgari, H.; Sabe, A.; Nezami, F. R.; Woo, J.; Aganj, I.
10.1101/2024.09.27.615510 — bioengineering — Posted on 2024-09-30
89 Optimal Frequency for Seizure Induction with Electroconvulsive Therapy and Magnetic Seizure Therapy
Peterchev, A. V.; Deng, Z.-D.; Sikes-Keilp, C.; Feuer, E. C.; Rosa, M. A.; Lisanby, S. H.
10.1101/2024.09.28.615333 — bioengineering — Posted on 2024-09-30
90 Biomechanical and Compositional Changes in the Murine Uterus with Age
Domingo, M. J. E.; Vanoven, T. N.; De Vita, R.; Florian-Rodriguez, M. E.; Miller, K. S.; Pence, I. J.
10.1101/2024.09.28.615592 — bioengineering — Posted on 2024-09-30
95 Roadkill is a crucial factor in the population decline of migratory monarch butterflies
Momeni-Dehaghi, I.; Fahrig, L.; Mitchell, G. W.; Rytwinski, T.; Hanson, J. O.; Bennett, J. R.
10.1101/2024.09.27.615542 — ecology — Posted on 2024-09-30
96 Diversification mitigates pesticide but not microplastic effects on bees without compromising rapeseed yield in China
Lin, W.; He, X.; Hu, J.; Balle, M.; Darras, K. F.; Jing, S.; Scherber, C.; Toledo-Hernandez, M.; Yan, Y.; Zhang, C. C.; Zeng, S.; Wanger, T. C.
10.1101/2024.09.28.615554 — ecology — Posted on 2024-09-30
99 On the diversity of nematode antagonists in an agricultural soil, and their steerability by root-knot nematode density and cover crops
Cazzaniga, S. G.; Belliard, P.; Van Steenbrugge, J. J.; Van den Elsen, S.; Lombaers, C.; Visser, J.; Macia Vicente, J.; Postma, J.; Mommer, L.; Helder, J.
10.1101/2024.09.27.615391 — ecology — Posted on 2024-09-30
101 Stiffening Symphony of Aging: How Senescent Osteocytes Lose Their Elastic Rhythm
Tilton, M.; Weivoda, M.; Astudillo Potes, M.; Gingery, A.; Liu, A. Y.; Tchkonia, T.; Lu, L.; Kirkland, J. L.
10.1101/2024.09.28.615588 — cell biology — Posted on 2024-09-30
102 MTALTCO1: a 259 amino-acid long mtDNA-encoded alternative protein that challenges conventional understandings of mitochondrial genomics
Robitaille, F.; Ben Hadj, A.; Campbell, A.; Nadeau-Lachance, L.; Niaison, T.; Choquette, T.; Roucou, X.; Angers, A.; Breton, S.
10.1101/2024.09.22.614361 — molecular biology — Posted on 2024-09-30
103 Damage-induced IL-18 stimulates thymic NK Cells limiting endogenous tissue regeneration
Granadier, D.; Cooper, K.; Kousa, A.; Acenas, D.; Lemarquis, A.; Hernandez, V.; Warren, M.; Iovino, L.; deRoos, P.; Lederer, E.; Shannon-Sevillano, S.; Kinsella, S.; Evandy, C.; van den Brink, M.; Dudakov, J.
10.1101/2024.09.27.615528 — immunology — Posted on 2024-09-30
104 Effect of the Environmental Mechanical Heterogeneity on T Cell Function
Pandit, J. J.; Yassin, A. A.-K.; Urena Martin, C.; Le Saux, G.; Porgador, A.; Schvartzman, M.
10.1101/2024.09.28.615572 — immunology — Posted on 2024-09-30
105 Activation of the endoplasmic reticulum stress regulator IRE1α compromises pulmonary host defenses
Sharma, A.; Heffernan, L. M.; Hoang, K.; Jeyaseelan, S.; Beavers, W. N.; Abuaita, B. H.
10.1101/2024.09.28.615286 — immunology — Posted on 2024-09-30
106 Active reconfiguration of neural task states
Ritz, H.; Jha, A.; Pillow, J. W.; Daw, N. D.; Cohen, J. D.
10.1101/2024.09.29.615736 — neuroscience — Posted on 2024-09-30
110 A Water Relaxation Atlas for Age and Region specific Metabolite Concentration Correction
Simegn, G. L.; Song, y.; Murali-Manohar, S.; Zollner, H. J.; Davies-Jenkins, C. W.; Simicic, D.; Hupfeld, K. E.; Gudmundson, A. T.; Musaka, E.; Carter, E.; Hui, S. C. N.; Yedavalli, V.; Oeltzschner, G. C. N.; Dean, D. C.; Ceritoglu, C.; Ratnanather, T.; Porges, E.; Edden, R.
10.1101/2024.09.27.615424 — neuroscience — Posted on 2024-09-30
116 LPS-induced delirium-like behavior and microglial activation in mice correlate with bispectral electroencephalography (BSEEG)
Nishiguchi, T.; Yamanishi, K.; Gorantla, N.; Shimura, A.; Seki, T.; Ishii, T.; Aoyama, B.; Malicoat, J. R.; Phuong, N. J.; Dye, N. J.; Yamanashi, T.; Iwata, M.; Shinozaki, G.
10.1101/2024.09.27.615556 — neuroscience — Posted on 2024-09-30
123 Measurement of cellular traction forces during confined migration
Hockenberry, M. A.; Ulmer, A. J.; Rapp, J. L.; Leibfarth, F. A.; Bear, J. E.; Legant, W.
10.1101/2024.09.27.615466 — biophysics — Posted on 2024-09-30
124 Reusable Microfluidic Chambers for Single-Molecule Microscopy
Alfehaid, J.; Kodikar, S. G.; Alhajri, T.; Kabir, M. L.; Balci, H.
10.1101/2024.09.27.615484 — biophysics — Posted on 2024-09-30
125 LC8 enhances 53BP1 foci through heterogeneous bridging of 53BP1 oligomers
Howe, J.; Walker, D.; Tengler, K.; Sonpatki, M.; Reardon, P. N.; Leung, J. W. C.; Barbar, E. J.
10.1101/2024.09.27.615446 — biophysics — Posted on 2024-09-30
130 Aspergillus nidulans cell wall integrity kinase, MpkA, impacts cellular phenotypes that alter mycelial-material mechanical properties
Gray, K.; Edwards, H.; Doan, A. G.; Huso, W.; Lee, J.; Pan, W.; Bolima, N.; Morse, M. E.; Yoda, S.; Gautam, I.; Harris, S.; Zupan, M.; Wang, T.; deCarvalho, T.; Marten, M. R.
10.1101/2024.09.28.615565 — bioengineering — Posted on 2024-09-30
132 Multiple stressors in river networks: local and downstream effects on freshwater macroinvertebrates
Burgazzi, G.; Juvigny-Khenafou, N. P. D.; Schreiner, V. C.; Manfrin, A.; Jupke, J.; Piggott, J.; Harvey, E.; Terui, A.; Leese, F.; Schaefer, R. B.
10.1101/2024.09.27.615445 — ecology — Posted on 2024-09-30
133 The Human Neural Cell Atlas of Zika Infection in developing human brain tissue: viralpathogenesis, innate immunity, and lineage reprogramming
Stokes, C.; Whitmore, L.; Moreno, D.; Malhotra, K.; Tisoncik-Go, J.; Tran, E.; Wren, N.; Glass, I.; Birth Defects Research Laboratory, ; Young, J. E.; Gale, M.
10.1101/2024.09.27.615512 — immunology — Posted on 2024-09-30
134 Granulysin antimicrobial activity promotes dormancy in Mycobacterium tuberculosis
Schmidiger, S.; McCaffrey, E. F.; Schmidt, J. M.; Abdul Hameed, O.; Mpina, M.; Tumbo, A.; Mfinanga, E.; Haraka, F.; Hiza, H.; Sasamalo, M.; Hella, J.; Walch, M.; Fellay, J.; Gagneux, S.; Reither, K.; Carballido, J. M.; Arbues, A.; Portevin, D.
10.1101/2024.09.27.615427 — immunology — Posted on 2024-09-30
135 Deep physico-chemical characterization of the serum antibody response using a dual-titration microspot assay
Kovacs, A.; Herincs, Z.; Papp, K.; Kaczmarek, J. Z.; Larsen, D. N.; Stage, P.; Bereczki, L.; Ujhelyi, E.; Pfeil, T.; Prechl, J.
10.1101/2023.03.14.532012 — immunology — Posted on 2024-09-30
138 Activation mapping in multi-center rat sensory-evoked functional MRI datasets using a unified pipeline.
Galteau, M. E.; Broadwater, M.; Chen, Y.; Desrosiers-Gregoire, G.; Gil, R.; Kaesser, J.; Kim, E.; Kiryagdi, P.; Lambers, H.; Liu, Y. Y.; Lopez-Gil, X.; MacNicol, E.; Mohebkhodaei, P.; N. De Oliveira, R. X.; Pereira, C. A.; Reimann, H. M.; Rivera-Olvera, A.; Selingue, E.; Sirmpilatze, N.; Strobelt, S.; Sumiyoshi, A.; Tham, C.; Tudela, R.; van Engelenburg, W. A.; Vrooman, R. M.; Wank, I.; Zhang, Y.; Baudewig, J.; Boretius, S.; Cash, D.; Chakravarty, M. M.; Chuang, K.-H.; Ciobanu, L.; Devenyi, G. A.; Faber, C.; Hess, A.; Homberg, J. R.; Jelescu, I. O.; Justicia, C.; Kawashima, R.; Niendorf, T.; S
10.1101/2024.09.27.615384 — neuroscience — Posted on 2024-09-30
143 New components of the community based DNA-repair mechanism in Sulfolobales
Recalde, A.; Wagner, A.; Sivabalasarma, S.; Yurmashava, A.; Fehr, N. P.; Thurm, R.; Le, T. N.; Koebler, C.; Wassmer, B.; Albers, S. V.; van Wolferen, M.
10.1101/2024.09.27.615169 — microbiology — Posted on 2024-09-30
148 A MEF2C transcripton factor network regulates proliferation of glomerular endothelial cells in diabetic kidney disease
Melo Ferreira, R.; Gisch, D. L.; Phillips, C. L.; Cheng, Y.-H.; Asthana, M.; Lake, B. B.; Bowen, W. S.; Fang, F.; Asghari, M.; Sabo, A.; Barwinska, D.; Ferkowicz, M. J.; Toto, R. D.; Sedor, J. R.; Rosas, S. E.; Bjornstad, P.; Hodgin, J. B.; Alpers, C. E.; Sarder, P.; Himelfarb, J.; Schaub, J. A.; Nair, V.; Winfree, S.; Sutton, T. A.; Kelly, K. J.; and The Kidney Precision Medicine Project, ; Kretzler, M.; Jain, S.; El-Achkar, T. M.; Dagher, P. C.; Eadon, M. T.
10.1101/2024.09.27.615250 — cell biology — Posted on 2024-09-30
149 AFG3L2-mediated proteolysis restricts mitochondrial biogenesis and gene expression in hypoxia
Chandragiri, S.; Grotehans, N.; Lasarzewski, Y.; Patron, M.; MacVicar, T.; Ohba, Y.; Hermans, S.; Rugarli, E.; Nolte, H.; Langer, T.
10.1101/2024.09.27.615438 — cell biology — Posted on 2024-09-30
156 Current Reporting Practices in Human Neuroscience Research
Gard, A. M. S.; Shariq, D.; Albrecht, A.; Lurie, A.; Kim, H. C.; Mitchell, C.; Hyde, L. W.
10.1101/2024.09.28.615619 — neuroscience — Posted on 2024-09-30
158 Identification of SLC45A4 as a pain gene encoding a neuronal polyamine transporter.
Middleton, S. J.; Markusson, S.; Akerlund, M.; Deme, J. C.; Tseng, M.; Li, W.; Zuberi, S. R.; Kuteyi, G.; Sarkies, P.; Baskozos, G.; Perez-Sanchez, J.; Hebert, H. L.; Toikumo, S.; Farah, A.; Maxwell, S.; Dong, Y. Y.; Kranzler, H. R.; Linley, J. E.; Smith, B. H.; Lea, S. M.; Parker, J. L.; Lyssenko, V.; Newstead, S.; Bennett, D.
10.1101/2024.09.25.615046 — neuroscience — Posted on 2024-09-30
159 Telomeres control human telomerase (hTERT) expression through non-telomeric TRF2
Sengupta, A.; Vinayagamurthy, S.; Soni, D.; Deb, R.; Mukherjee, A. K.; Dutta, S.; Jaiswal, J.; Yadav, M.; Sharma, S.; Bagri, S.; Roy, S. S.; Poonia, P.; Singh, A.; Khanna, D.; Bhatt, A. K.; Sharma, A.; Saurav, S.; Motiani, R. K.; Chowdhury, S.
10.1101/2023.10.09.561466 — cancer biology — Posted on 2024-09-30
163 Zebrafish glial-vascular interactions progressively expand over the course of brain development
Gall, L. G.; Stains, C. M.; Freitas-Andrade, M.; Jia, B. Z.; Patel, N.; Megason, S. G.; Lacoste, B.; O'Brown, N. M.
10.1101/2024.09.27.615488 — developmental biology — Posted on 2024-09-30
164 TMPRSS2 activation of Omicron lineage Spike glycoprotein is regulated by Collectrin-like domain of ACE2
Aggarwal, A.; Fichter, C.; Milogiannakis, V.; Ison, T.; Ruiz Silva, M.; Esneau, C.; Bartlett, N.; Burrell, L.; Patel, S.; Churchill, M.; Angelovich, T.; Parry, R.; Sng, J. D.; Neely, G. G.; Moreno, C. L.; Loo, L.; Brilot, F.; Kok, J.; Sintchenko, V.; Chandra, D.; Kindinger, A.; Akerman, A.; Yeang, M.; Walker, G. J.; Rawlinson, W. D.; Kelleher, A. D.; Khromykh, A.; Turville, S. G.
10.1101/2023.09.22.558930 — microbiology — Posted on 2024-09-30
166 Breaking the cycle: How targeting CD44v6/MET signaling disrupts colorectal cancer cell plasticity
Sonnentag, S. J.; Goldbach, S.; Hoch, D.; Andrieux, G.; Becker, J.; Fromm, h.; Munoz-Sagredo, L.; Heneka, Y. M.; Grimm, D.; Greten, F.; Orian-Rousseau, V.
10.1101/2024.09.27.614761 — cancer biology — Posted on 2024-09-30
167 Long non-coding RNA UCA1 affects chromatin remodeling via SMARCA2-containing SWI/SNF complex in human colorectal cancer.
Neve, B.; Hadj Bachir, E.; Duchene, B.; Souidi, M.; Figeac, M.; Meneboo, J.-P.; Leteurtre, E.; OrgaRES consortium, ; Jonckheere, N.; Vincent, A.; Van Seuningen, I.
10.1101/2024.09.27.615411 — cancer biology — Posted on 2024-09-30
168 Novel preclinical model of human lung cancer cachexia
Snoke, D. B.; van der Velden, J. L.; Bellefleur, E. R.; Dearborn, J. S.; Lenahan, S. M.; Heininger, S. C. J.; Ather, J. L.; Sarausky, H.; Stephenson, D.; Reisz, J. A.; D'Alessandro, A.; Majumdar, D.; Janssen-Heininger, Y. M. W.; Poynter, M. E.; Seward, D. J.; Toth, M. J.
10.1101/2024.09.27.615385 — cancer biology — Posted on 2024-09-30
169 UPR-induced intracellular C5aR1 promotes adaptation to the hypoxic tumour microenvironment by regulating tumour cell fate
Suwa, T.; Lee, K.; Chai, I.; Clark, H.; MacLean, D. J.; Machado, N.; Rodriguez-Berriguete, G.; Higgins, G. S.; Hammond, E. M.; Olcina, M. M.
10.1101/2024.09.27.615431 — cancer biology — Posted on 2024-09-30
171 Myocardial Endoglin Regulates Cardiomyocyte Proliferation and Cardiac Regeneration
Sorensen, D. W.; Tan, P. M.; Garay, B. I.; Solinsky, J.; Yucel, D.; Zhang, M. J.; Galvin, C.; Elsenpeter, H.; Mikkila, J.; Jerdee, K.; O Connell, T. D.; Molkentin, J. D.; Perlingeiro, R. C. R.; Kawakami, Y.; Saucerman, J. J.; van Berlo, J. H.
10.1101/2024.09.27.615380 — genetics — Posted on 2024-09-30
172 Ancient origin and high diversity of zymocin-like killer toxins in the budding yeast subphylum
Heneghan, P. G.; Salzberg, L. I.; O Cinneide, E.; Dewald, J. A.; Weinberg, C. E.; Wolfe, K. H.
10.1101/2024.09.27.615389 — evolutionary biology — Posted on 2024-09-30
174 Molecular signatures of altered energy metabolism and circadian rhythm perturbations in a model of extra-nigral Synucleinopathy.
Lin, L.; Jensen, N. M.; Ferreira, S. A.; Delaidelli, A.; Gomes Moreira, D.; Ahlgreen, O.; Richner, M.; Sorensen, P.; Romero-Ramos, M.; Vaegter, C.; Jensen, P. H.; Mackenzie, I. R.; Nyengaard, J. R.; Jan, A.
10.1101/2024.09.27.615378 — neuroscience — Posted on 2024-09-30
175 Generation of synthetic TSPO PET maps from structural MRI images
Ferrante, M.; Inglese, M.; Brusaferri, L.; Toschi, N.; Loggia, M. L.
10.1101/2024.09.27.615379 — neuroscience — Posted on 2024-09-30
177 An evolutionarily conserved Hox-Gbx segmentation code in the rice coral Montipora capitata
He, S.; Rangel-Huerta, E.; Hill, E.; Ellington, L.; Chen, S.; Robb, S.; Majerov, E.; Drury, C.; Gibson, M.
10.1101/2024.09.29.615694 — evolutionary biology — Posted on 2024-09-30
178 Video-based biomechanical analysis captures disease-specific movement signatures of different neuromuscular diseases
Ruth, P.; Uhlrich, S. D.; de Monts, C.; Falisse, A.; Covitz, S.; Vogt-Domke, S.; Muccini, J.; Day, J.; Duong, T.; Delp, S.
10.1101/2024.09.26.613967 — bioengineering — Posted on 2024-09-30
179 Heterogeneous plasticity of amygdala interneurons in associative learning and extinction
Favila, N.; Capece Marsico, J.; Escribano, B.; Pacheco, C. M.; Bitterman, Y.; Gründemann, J.; Lüthi, A.; Krabbe, S.
10.1101/2024.09.29.612271 — neuroscience — Posted on 2024-09-29
180 The Hurst exponent as a marker of inhibition in the developing brain
Nishio, M.; Ellwood-Lowe, M.; Woodburn, M.; McDermott, C. L.; Park, A.; Tooley, U.; Boroshok, A. L.; Grandjean, J.; Mackey, A. P.
10.1101/2024.09.29.615675 — neuroscience — Posted on 2024-09-29
182 Avian influenza virus surveillance across New Zealand and its subantarctic islands detects H1N9 in migratory shorebirds, but not 2.3.4.4b HPAI H5N1
Waller, S. J.; Wierenga, J. R.; Heremia, L.; Darnley, J. A.; de Vries, I.; Dubrulle, J.; Robinson, Z.; Miller, A.; Niebuhr, C. N.; Melville, D.; Schuckard, R.; Battley, P. F.; Wille, M.; Cole, R.; McInnes, K.; Winter, D.; Geoghegan, J. L.
10.1101/2024.09.29.615640 — microbiology — Posted on 2024-09-29
186 Pexidartinib plus FLT3-directed CAR-Macrophage for the treatment of FLT3-ITD-mutated acute myeloid leukemia in preclinical model
Chen, F.; Lv, M.-H.; Li, C.-W.; Zhang, Y.-Q.; Wei, Z.-X.; Yuan, Z.; Cao, J.-Y.; Yang, X.; Xu, J.-B.; Wang, L.; He, B.-L.
10.1101/2024.09.27.615313 — cancer biology — Posted on 2024-09-29
190 Plasmid conjugation drives within-patient plasmid diversity
Grayson, F.; Loman, L.; Nonnenmacher, T.; Pople, D.; Pollard, J.; Patel, B.; Williams, D.; Hounsome, L.; Hopkins, K. L.; Robotham, J. V.; Ledda, A.
10.1101/2024.09.27.615342 — bioinformatics — Posted on 2024-09-29
191 Identifying similar populations across independent single cell studies without data integration
Gonzalez-Velasco, O.; Simon, M.; Yilmaz, R.; Parlato, R.; Weishaupt, J.; D. Imbusch, C.; Brors, B.
10.1101/2024.09.27.615367 — bioinformatics — Posted on 2024-09-29
192 Radical Protein Footprinting in Mammalian Whole Blood
Tobin, L.; Misra, S. K.; Liu, H.; Jones, L. M.; Sharp, J. S.
10.1101/2024.09.29.615683 — biochemistry — Posted on 2024-09-29
193 Ancient environmental DNA indicates limited human impact on marine biodiversity in pre-industrial Iceland
Holman, L. E.; Arfaoui, E. M. R.; Pedersen, L. B.; Farnsworth, W. R.; Ascough, P.; Butler, P.; Guthmundsdottir, E. R.; Reynolds, D. J.; Trofimova, T.; Wilkin, J. T. R.; Caroe, C.; Froslev, T. G.; Harrison, R.; Gopalakrishnan, S.; Pedersen, M. W.; Scourse, J.; Bohmann, K.
10.1101/2024.09.29.615643 — ecology — Posted on 2024-09-29
197 Astrocyte-derived PEA116 increases adult hippocampal neurogenesis and confers stress resilience
Carron, C.; Casse, F.; Sultan, S.; Larrieu, T.; Richetin, K.; Espourteille, J.; Robadey, N.; Vilademunt, M.; Sagner, A.; Petrelli, F.; Knobloch, M.; Beckervordersandforth, R.; Toni, N.
10.1101/2024.09.27.615330 — neuroscience — Posted on 2024-09-29
198 Deficiency of actin depolymerizing factors ADF/Cfl1 in microglia decreases motility and impairs memory
Crux, S.; Roggan, M. D.; Poll, S.; Nebeling, F. C.; Schiweck, J.; Mittag, M.; Musacchio, F.; Steffen, J.; Wolff, K.; Baral, A.; Witke, W.; Bradke, F.; Fuhrmann, M.
10.1101/2024.09.27.615114 — neuroscience — Posted on 2024-09-29
199 Implications of carbon source-sink feedbacks for plant growth responses to environmental factors
Friend, A. D.; Chen, Y.; Eckes-Shephard, A. H.; Fonti, P.; Hellmann, E.; Rademacher, T. T.; Richardson, A. D.; Thomas, P. R.
10.1101/2024.09.27.615358 — plant biology — Posted on 2024-09-29
200 Identifying Agronomic, Nutrition and Leaf Vein Quantitative Trait Loci in the Orphan Crop Gynandropsis gynandra
Simpson, C. J. C.; Sogbohossou, D. E. O.; Reeves, G.; Schranz, M. E.; Singh, P.; Hibberd, J. M.
10.1101/2024.09.28.615607 — plant biology — Posted on 2024-09-29
202 GERMIN3 plays a role in plasmodesmatal gating to regulate meristem activation related to tuberisation, tuber dormancy release and stem branching in potato
Campbell, R.; Cowan, G.; Wurzinger, B.; Ducreux, L. J.; Dessoly, J.; Guo, W.; Zhang, R.; Morris, J.; Hedley, P. E.; Wahl, V.; Taylor, M. A.; Hancock, R. D.
10.1101/2024.09.28.615581 — plant biology — Posted on 2024-09-29
203 Glutamate Transport Proteins and Metabolic Enzymes are Poor Prognostic Factors in Invasive Lobular Carcinoma
Young, T. A.; Bahnassy, S.; Abalum, T. C.; Pope, E. A.; Rivera, A. T.; Fernandez, A. I.; Olukoya, A. O.; Mobin, D.; Ranjit, S.; Libbey, N. E.; Persaud, S.; Rozeboom, A. M.; Chaldekas, K.; Harris, B. T.; Madak-Erdogan, Z.; Sottnik, J. L.; Sikora, M. J.; Riggins, R. B.
10.1101/2024.09.29.615681 — cancer biology — Posted on 2024-09-29
206 Sirtuin 6 is a histone delactylase
Nickel, G. A.; Pederson, N. J.; none, F.; Yang, Z.; Bulf, J.; Diehl, K. L.
10.1101/2024.09.28.615627 — biochemistry — Posted on 2024-09-29
207 Characterization of hairpin loops and cruciforms across 118,065 genomes spanning the tree of life
Chantzi, N.; Moeckel, C.; Chan, C. S. Y.; Nayak, A.; Wang, G.; Mouratidis, I.; Chartoumpekis, D.; Vasquez, K. M.; Georgakopoulos-Soares, I.
10.1101/2024.09.29.615628 — genomics — Posted on 2024-09-29
208 Genetic dissection of MutL complexes in Arabidopsis meiosis
Kbiri, N.; Fernandez-Jimenez, N.; Dziegielewski, W.; Saez-Zarate, E.; Pele, A.; Mata-Villanueva, A.; Santos, J. L.; Pradillo, M.; Ziolkowski, P. A.
10.1101/2024.09.28.615604 — genetics — Posted on 2024-09-29
218 AMPK agonism optimizes the in vivo persistence and anti-leukemia efficacy of chimeric antigen receptor T cells
Braverman, E.; Qin, M.; Schuler, H. T.; Brown, H.; Wittmann, C.; Ramgopal, A.; Kemp, F.; Mullett, S.; Yang, A.; Poholek, A. C.; Gelhaus, S. L.; Byersdorfer, C. A.
10.1101/2024.09.26.615290 — immunology — Posted on 2024-09-29
221 A Collagen Triple Helix without the Super Helical Twist
Kreutzberger, M. A. B.; Yu, L. T.; Hancu, M. C.; Purdy, M. D.; Osinski, T.; Kasson, P.; Egelman, E. H.; Hartgerink, J. D.
10.1101/2024.09.26.615199 — biophysics — Posted on 2024-09-29
225 Microfluidic Modulation of Microvasculature in Microdissected Tumors
Nguyen, T. N. H.; Horowitz, L. F.; Nguyen, B.; Lockhart, E.; Zhu, S.; Gujral, T. S.; Folch, A.
10.1101/2024.09.26.615278 — bioengineering — Posted on 2024-09-29
233 Mapping and engineering RNA-controlled architecture of the multiphase nucleolus
Quinodoz, S. A.; Jiang, L.; Abu-Alfa, A. A.; Comi, T. J.; Zhao, H.; Yu, Q.; Wiesner, L. W.; Botello, J. F.; Donlic, A.; Soehalim, E.; Zorbas, C.; Wacheul, L.; Kosmrlj, A.; Lafontaine, D. L.; Klinge, S.; Brangwynne, C. P.
10.1101/2024.09.28.615444 — cell biology — Posted on 2024-09-29
236 Alternative splicing of transposable elements in human breast cancer
Nesta, A. V.; Veiga, D. F. T.; Banchereau, J.; Anczukow, O.; Beck, C. R.
10.1101/2024.09.26.615242 — genomics — Posted on 2024-09-29
238 A Kinematic Deviation Index (KDI) for Evaluation of Forelimb Function in Rodents
Espin, A. T.; Bernstein, A.; Soliman, M.; Jara, J. S.; Moreno-Lopez, Y.; Hollis, E.
10.1101/2024.09.26.615237 — neuroscience — Posted on 2024-09-29
239 Reproducible Sex Differences in Personalized Functional Network Topography in Youth
Keller, A. S.; Sun, K. Y.; Francisco, A.; Robinson, H.; Beydler, E.; Bassett, D. S.; Cieslak, M.; Cui, Z.; Davatzikos, C.; Fan, Y.; Gardner, M.; Kishton, R.; Kornfield, S. L.; Larsen, B.; Li, H.; Linder, I.; Pines, A.; Pritschet, L.; Raznahan, A.; Roalf, D. R.; Seidlitz, J.; Shafiei, G.; Shinohara, R. T.; Wolf, D. H.; Alexander-Bloch, A.; Satterthwaite, T. D.; Shanmugan, S.
10.1101/2024.09.26.615061 — neuroscience — Posted on 2024-09-29
241 Enhancer AAV toolbox for accessing and perturbing striatal cell types and circuits
Hunker, A. C.; Wirthlin, M. E.; Gill, G.; Johansen, N. J.; Hooper, M.; Omstead, V.; Taskin, N.; Weed, N.; Vargas, S.; Bendrick, J. L.; Gore, B.; Ben-Simon, Y.; Bishaw, Y.; Opitz-Araya, X.; Martinez, R. A.; Way, S.; Thyagarajan, B.; Lerma, M. N.; Laird, W.; Otto, S.; Sanchez, R. E. A.; Alexander, J. R.; Amaya, A.; Amster, A.; Ayala, A.; Baker, P. M.; Barcelli, T.; Barta, S.; Bertagnolli, D.; Bielstein, C.; Bishwakarma, P.; Bowlus, J.; Boyer, G.; Brouner, K.; Casian, B.; Casper, T.; Chakka, A. B.; Chakrabarty, R.; Clark, M.; Colbert, K.; Daniel, S.; Dawe, T.; Departee, M.; DiValentin, P.; Donadi
10.1101/2024.09.27.615553 — neuroscience — Posted on 2024-09-29
242 Paralog protein compensation preserves protein-protein interaction networks following gene loss in cancer
Venkatesh, A.; Quinn, N.; Upadhya, S. R.; De Kegel, B.; Carrancio, A. B.; Lefeivre, T.; Dennler, O.; Wynne, K.; Von Kriegsheim, A.; Ryan, C. J.
10.1101/2024.09.26.615228 — systems biology — Posted on 2024-09-29
244 Metabolic Stress Accelerates Dysregulated Synovial Macrophage-Fibroblast Communication and Htra1 Overproduction in Osteoarthritis
Blackler, G.; Klapak, J.; Guo, Q.; Philpott, H. T.; Jiang, H.; Ocica, D.; Del Sordo, L.; Fiset, B.; Walsh, L. A.; Appleton, C. T.; On behalf of the WOREO Knee Study Group,
10.1101/2024.09.26.615231 — physiology — Posted on 2024-09-29
246 Somatic mutant selection is altered by prior NOTCH1 mutation in aging esophageal epithelium
Jones, P. H.; Fowler, J. C.; Abby, E.; Sood, R. K.; King, C.; Abnizova, I.; Ong, S. H.; Lynch Williams, F.; Hall, M. W. J.; Hall, B. A.
10.1101/2024.09.26.615123 — genomics — Posted on 2024-09-29
248 Cave Adaptation Favors Aging Resilience in the Mexican Tetra
Cobham, A. E.; Kenzior, A.; Morales-Sosa, P.; Javier, J.; Swanson, S.; Wood, C.; Rohner, N.
10.1101/2024.09.26.615235 — evolutionary biology — Posted on 2024-09-29
249 Cannabis smoke and oral Δ9THC enhance working memory in aged but not young adult subjects
Zequeira, S.; Gazarov, E. A.; Güvenli, A. A.; Berthold, E. C.; Senetra, A. S.; Febo, M.; Hiranita, T.; McMahon, L. R.; Sharma, A.; McCurdy, C. R.; Setlow, B.; Bizon, J. L.
10.1101/2024.09.26.615028 — neuroscience — Posted on 2024-09-29
250 Rapid prediction of thermodynamically destabilizing tyrosine phosphorylations in cancers
Woodard, J. C.; Liu, Z.; Chegini, A. M.; Tian, J.; Bhowmick, R.; Pennathur, S.; Mashaghi, A.; brender, j.; Chandrasekaran, S.
10.1101/2024.09.26.614998 — systems biology — Posted on 2024-09-29
252 Oncogenic and teratogenic effects of p53Y217C, a mouse model of the human hotspot mutant p53Y220C
Jaber, S.; Eldawra, E.; Rakotopare, J.; Gabriel, M.; Lejour, V.; Simeonova, I.; Morillon, A.; Bardot, B.; Toledo, F.
10.1101/2024.09.26.615223 — cancer biology — Posted on 2024-09-29
259 KaryoTap Enables Aneuploidy Detection in Thousands of Single Human Cells
Mays, J. C.; Mei, S.; Kogenaru, M.; Quysbertf, H.; Bosco, N.; Zhao, X.; Bianchi, J. J.; Goldberg, A.; Kidiyoor, G. R.; Holt, L. J.; Fenyö, D.; Davoli, T.
10.1101/2023.09.08.555746 — genomics — Posted on 2024-09-29
263 Occurrence of "under-the-radar" antibiotic resistance in anthropogenically affected produce
Davidovich, C.; Erokhina, K.; Gupta, C. L.; Zhu, Y.-G.; Su, J.-Q.; Djordjevic, S. P.; Wyrsch, E. R.; Blum, S. E.; Cytryn, E.
10.1101/2024.09.26.615221 — microbiology — Posted on 2024-09-29
265 Compartmentalized dendritic plasticity in the retrosplenial cortex integrates memories across time
Sehgal, M.; Almeida-Filho, D.; Kastellakis, G.; Kim, S.; Lee, J.; Shen, Y.; Huang, S.; Lavi, A.; Fernandes, G.; Martin, S.; Mejia, I. D.; Pekcan, A.; Wu, M. S.; Heo, W. D.; Poirazi, P.; Trachtenberg, J. T.; Silva, A. J.
10.1101/2021.10.28.466343 — neuroscience — Posted on 2024-09-29
269 The AAA+ protein Msp1 recognizes substrates by a hydrophobic mismatch
Fresenius, H. L.; Gaur, D.; Smith, B.; Acquaviva, B.; Wohlever, M. L.
10.1101/2023.07.11.548587 — biochemistry — Posted on 2024-09-29
270 Specific Mitotic Events Drive Cytoskeletal Remodeling Required for Left-Right Organizer Development
Wu, Y.; Lan, Y.; Ononiwu, F.; Poole, A.; Rasmussen, K.; Da Silva, J.; Shamil, A. W.; Jao, L.-E.; Hehnly, H.
10.1101/2024.05.12.593765 — developmental biology — Posted on 2024-09-29
272 CCR5 antagonists as neuroprotective and stroke recovery enhancing agents: a preclinical systematic review and meta-analysis
Sharif, A.; Jeffers, M. S.; Fergusson, D. A.; Bapuji, R.; Nicholls, S. G.; Humphrey, J.; Johnston, W.; Mitchell, E.; Speirs, M.-A.; Stronghill, L.; Vuckovic, M.; Wulf, S.; Shorr, R.; Dowlatshahi, D.; Corbett, D.; Lalu, M. M.
10.1101/2024.09.25.614925 — neuroscience — Posted on 2024-09-29
273 Inter-Kingdom Interactions and Environmental Influences on the Oral Microbiome in Severe Early Childhood Caries
Weng, L.; Cui, Y.; Jian, W.; Zhang, Y.; Pang, L.; Cao, Y.; Zhou, Y.; Liu, W.; Lin, H.; Tao, Y.
10.1101/2024.09.26.615216 — microbiology — Posted on 2024-09-29
274 Genetic requirements of Mycobacterium tuberculosis for survival under pathogen-specific immunity
James, K. S.; Jain, N.; Witzl, K.; Cicchetti, N.; Fortune, S. M.; Ioerger, T. R.; Martinot, A. J.; Carey, A. F.
10.1101/2024.09.26.615000 — microbiology — Posted on 2024-09-29
276 Amphetamine increases timing variability by degrading prefrontal ramping activity
Weber, M. A.; Sivakumar, K.; Kirkpatrick, B. Q.; Stutt, H. R.; Tabakovic, E. E.; Bova, A. S.; Kim, Y.-c.; Narayanan, N. S.
10.1101/2024.09.26.615252 — neuroscience — Posted on 2024-09-29
278 Estimating sampling and laboratory capacity for a simulated African swine fever outbreak in the United States
Galvis, J. A.; Satici, M. Y.; Sykes, A. L.; OHara, K. C.; Rochette, L.; Roberts, D.; Machado, G.
10.1101/2024.09.26.615206 — ecology — Posted on 2024-09-29
279 Dnmt1-deficiency in PV interneurons alters cortical circuit function and leads to depression-like behavior
Linde, J.; Nabbefeld, G.; Graff, S.; Yildiz, C. B.; Pensold, D.; Reichard, J.; Hermanns, M.; Kampa, B.; Urbach, A.; Musall, S.; Zimmer-Bensch, G. M.
10.1101/2024.09.28.615593 — neuroscience — Posted on 2024-09-29
281 Ligase-mediated programmable genomic integration (L-PGI): an efficient site-specific gene editing system that overcomes the limitations of reverse transcriptase-based editing systems
Nan, A. X.; Chickering, M.; Bartolome, C.; Shadija, N.; Li, D.; Estes, B.; Stetina, J. V.; Li, W.; Andresen, J.; Cochrane, J. C.; Bai, C.; Gatlin, J.; Wang, J.; Norouzi, D.; Kumar, S.; Dunyak, M. T.; Chavez, L.; Seth, A.; Halperin, S.; Finn, J. D.; Xie, J.
10.1101/2024.09.27.615478 — bioengineering — Posted on 2024-09-29
283 The transcriptomic response of cells of the thermophilic bacterium G. icigianus to THz irradiation
Bryanskaya, A.; Peltek, S.; Bannikova, S.; Khlebodarova, T.; Uvarova, Y.; Mukhin, A.; Vasiliev, G.; Scheglov, M.; Shipova, A.; Vasiliev?, A.; Oshchepkov, D.; Popik, V.
10.1101/2024.09.25.614926 — genetics — Posted on 2024-09-28
284 Cataloguing the postnatal small intestinal transcriptome during the period of susceptibility to necrotizing enterocolitis
Oliveria, L. F. S.; Wu, Y.-S.; Dasuri, V. S.; Harrington, A. W.; Olaloye, O.; Goldsmith, J. D.; Breault, D. T.; Konnikova, L.; O'Connell, A. E.
10.1101/2024.09.25.612672 — developmental biology — Posted on 2024-09-28
285 Unwrapping the ciliary coat: high-resolution structure and function of the ciliary glycocalyx
Hoepfner, L. M.; Nievergelt, A. P.; Martino, F.; Scholz, M.; Foster, H. E.; Rodenfels, J.; von Appen, A.; Hippler, M.; Pigino, G.
10.1101/2024.09.28.615573 — cell biology — Posted on 2024-09-29
286 Identification and characterization of ugpE required for the full virulence of Streptococcus suis
Yang, Q.; Li, N.; Tian, Y.; Liang, Q.; Zhao, M.; Chu, H.; Gong, Y.; Wu, T.; Wei, S.; Wang, H.; Yan, G.; Li, F.; Lei, L.
10.1101/2024.09.25.615082 — microbiology — Posted on 2024-09-28
287 Inter-kingdom signaling by the Legionella autoinducer LAI-1 involves the antimicrobial guanylate binding protein GBP
Solger, F.; Rauch, J.; Vormittag, S.; Fan, M.; Raykov, L.; Charki, P.; Soldati, T.; Seibel, J.; Hilbi, H.
10.1101/2024.09.27.615321 — microbiology — Posted on 2024-09-28
288 PRMT1 Modulates Alternative Splicing to Enhance HPV18 mRNA Stability and Promote the Establishment of Infection
Williams, D. E.; King, K. M.; Jackson, R.; Kuehner, F.; Arnoldy, C.; Marroquin, J. N.; Tobey, I.; Banka, A.; Ragonese, S.; Van Doorslaer, K.
10.1101/2024.09.26.614592 — microbiology — Posted on 2024-09-28
289 Impact of AIM2 on HNSCC Development
Reinartz, D. M.; Escamilla-Rivera, V.; Tribble, S. L.; Caulin, C.; Wilson, J. E.
10.1101/2024.09.27.615454 — immunology — Posted on 2024-09-28
291 Deep learning facilitates precise identification of disease-resistance genes in plants
Liu, Z.; Wang, X.; Cao, S.; Lei, T.; Chenzhu, Y.; Zhang, M.; Liu, Z.; Lu, J.; Ma, W.; Su, B.; Wang, Y.; Zhou, Y.
10.1101/2024.09.26.615248 — bioinformatics — Posted on 2024-09-28
292 Increased bone inflammation in type 2 diabetes and obesity correlates with Wnt signaling downregulation and reduced bone strength
Leanza, G.; Faraj, M.; Cannata, F.; Viola, V.; Pellegrini, N.; Tramontana, F.; Pedone, C.; Vadala, G.; Piccoli, A.; Strollo, R.; Zalfa, F.; Civitelli, R.; Maccarrone, M.; Papalia, R.; Napoli, N.
10.1101/2024.09.26.615119 — biochemistry — Posted on 2024-09-28
294 Modelling trypanosome motility
Overberg, F. A.; Jamshidi Khameneh, N.; Krueger, T.; Engstler, M.; Gompper, G.; Fedosov, D.
10.1101/2024.09.27.615450 — biophysics — Posted on 2024-09-28
295 Mechanism of allosteric activation in human mitochondrial ClpP protease
Goncalves, M. M.; Uday, A. B.; Forrester, T. J.; Currie, S. Q.; Kim, A. S.; Feng, Y.; Jitkova, Y.; Velyvis, A.; Harkness, R. W.; Kimber, M. S.; Schimmer, A. D.; Zeytuni, N.; Vahidi, S.
10.1101/2024.09.27.615468 — biochemistry — Posted on 2024-09-28
298 Earlier endosomal escape improves the catalytic activity of delivered enzyme cargo
Vazquez Maldonado, A. L.; Chen, T.; Rodriguez, D.; Zoltek, M.; Schepartz, A.
10.1101/2024.09.27.615476 — biochemistry — Posted on 2024-09-28
299 Identification of the drug/metabolite transporter 1 as a marker of quinine resistance in a NF54xCam3.II P. falciparum genetic cross.
Kanai, M.; Mok, S.; Yeo, T.; Shears, M. J.; Ross, L. S.; Jeon, J. H.; Narwal, S.; Haile, M. T.; Tripathi, A. K.; Mlambo, G.; Kim, J.; Gil-Iturbe, E.; Okombo, J.; Fairhurst, K. J.; Bloxham, T.; Bridgford, J. L.; Sheth, T.; Park, H.; Rozenberg, F. D.; Quick, M.; Mancia, F.; Lee, M. C.; Small-Saunders, J. L.; Uhlemann, A.-C.; Sinnis, P.; Fidock, D. A.
10.1101/2024.09.27.615529 — genetics — Posted on 2024-09-28
300 Outer membrane changes enable evolutionary escape from bacterial predation
Mridha, S.; Loose, S.-L.; Mattmann, O. C.; Isele, S.; Kuemmerli, R.; Huwiler, S. G.
10.1101/2024.09.27.615459 — evolutionary biology — Posted on 2024-09-28
301 AAV9-mediated targeting of natural antisense transcript as a novel treatment for Dravet Syndrome
Antinao Diaz, J. F.; Chilcott, E.; Almacellas Barbanoj, A.; Keegan, A.; McTague, A.; Cross, J. H.; Schorge, S.; Lignani, G.; Waddington, S. N.; Karda, R.
10.1101/2024.09.27.615323 — molecular biology — Posted on 2024-09-28
302 Potent and Selective SETDB1 Covalent Negative Allosteric Modulator Reduces Methyltransferase Activity in Cells
Uguen, M.; Shell, D. J.; Silva, M.; Deng, Y.; Li, F.; Szewczyk, M.; Yang, K.; Zhao, Y.; Stashko, M. A.; Norris-Drouin, J. L.; Waybright, J. M.; Beldar, S.; Rectenwald, J. M.; Mordant, A. L.; Webb, T. S.; Herring, L. E.; Arrowsmith, C. H.; Ackloo, S.; Gygi, S. P.; McGinty, R. K.; Barsyte-Lovejoy, D.; Liu, P.; Halabelian, L.; James, L. I.; Pearce, K. H.; Frye, S. V.
10.1101/2024.09.27.615363 — molecular biology — Posted on 2024-09-28
303 Megabase-scale loss of heterozygosity provoked by CRISPR-Cas9 DNA double-strand breaks
Regan, S. B.; Medhi, D.; White, T. B.; Jiang, Y.-Z.; Jia, S.; Deng, Q.; Jasin, M.
10.1101/2024.09.27.615517 — molecular biology — Posted on 2024-09-28
304 Zebrafish Pol-Theta and Human Pol-Theta, Orthologues with Homologous Function
Thomas, C.; Green, S.; Kimball, L.; Schmidtke, I.; Rothwell, L.; Griffin, M.; Par, I.; Schobel, S.; Palacio, Y.; Towle-Weicksel, J. B.; Weicksel, S.
10.1101/2024.09.27.615541 — molecular biology — Posted on 2024-09-28
305 Loss of Ing4 enhances hematopoietic regeneration in multipotent progenitor cells
Anderson, G. A.; Hernandex, M.; Quinde, C. A.; Thompson, Z.; Rodriguez, M.; Binder-Blaser, V.; Taylor, A. M.; Kathrein, K. L.
10.1101/2024.09.27.615522 — molecular biology — Posted on 2024-09-28
306 Accurate quantitation of 16S gene copies in low biomass samples post-antibiotic treatment through deep sequencing with a balanced nucleotide synthetic spike-in approach
Chang, C.-C.; Huang, L.; Jin, Y.; Jamal, M. A.; Hayase, E.; Halsey, T. M.; Ortega, M. R.; Pham, D.; Glover, I.; Flores, I.; McDaniel, L. K.; Prasad, R.; Peterson, C. B.; Jenq, R. R.
10.1101/2024.09.27.615519 — microbiology — Posted on 2024-09-28
308 Tailocin-mediated interactions in Soft Rot Pectobacteriaceae
Borowicz, M.; Krzyzanowska, D. M.; Sobolewska, M.; Narajczyk, M.; Mruk, I.; Czaplewska, P.; Pedron, J.; Barny, M.-A.; Yves Canto, P.; Dziadkowiec, J.; Czajkowski, R.
10.1101/2024.09.28.615580 — microbiology — Posted on 2024-09-28
309 Genome-directed study uncovers a family of phospholipases and highlights the diversity of Salmonella T6SS effectors.
Nicastro, G. G.; Sibinelli-Sousa, S.; Hespanhol, J. T.; Santos, T. W.; Munoz, J. P.; Santos, R. S.; Araujo-Silva, A. L.; Perez-Sepulveda, B. M.; Miyamoto, S.; Aravind, L.; de Souza, R. F.; Bayer-Santos, E.
10.1101/2024.09.27.615498 — microbiology — Posted on 2024-09-28
312 An amphiregulin reporter mouse enables transcriptional and clonal expansion analysis of reparative lung Treg cells
Loffredo, L. F.; Kaiser, K. A.; Kornberg, A.; Rao, S.; de los Santos-Alexis, K.; Han, A.; Arpaia, N.
10.1101/2024.09.26.615245 — immunology — Posted on 2024-09-28
313 Comparative Analysis of AAV Serotypes for Transduction of Olfactory Sensory Neurons
Belfort, B. D.; Jia, J. D.; Garza, A. R.; Insalaco, A. M.; McGinnis, J. P.; Pekarek, B. T.; Ortiz, J.; Tepe, B.; Chen, H.; Liu, Z.; Arenkiel, B. R.
10.1101/2024.09.26.615247 — neuroscience — Posted on 2024-09-28
319 Enzyme Activity Regulates Substrate Diffusion by Modulating Viscosity in Crowded Milieu
Bevilacqua, A.; Maciel, M. R.; Pascarelli, S.; Dindo, M.; Shen, A. Q.; Laurino, P.
10.1101/2024.09.28.615560 — biochemistry — Posted on 2024-09-28
320 A Genetically Encoded Fluorescent Biosensor for Intracellular Measurement of Malonyl-CoA
Ranzau, B. L.; Robinson, T. D.; Scully, J. M.; Kapelczack, E. D.; Dean, T. S.; TeSlaa, T.; Schmitt, D. L.
10.1101/2024.09.27.615526 — biochemistry — Posted on 2024-09-28
321 irCLIP-RNP and Re-CLIP reveal patterns of dynamic protein associations on RNA
DUCOLI, L.; Zarnegar, B.; Porter, D.; Meyers, R.; Miao, W.; Riley, N.; Srinivasan, S.; Jackrazi, L.; Yang, Y.-Y.; Li, Z.; Wang, Y.; Bertozzi, C.; Flynn, R.; Khavari, P.
10.1101/2024.09.27.615518 — molecular biology — Posted on 2024-09-28
322 A cortical circuit for orchestrating oromanual food manipulation
An, X.; Matho, K. S.; Li, Y.; Mohan, H.; Xu, X. H.; Whishaw, I.; Kepecs, A.; Huang, Z. J.
10.1101/2022.12.03.518964 — neuroscience — Posted on 2024-09-28
323 MirGeneDB 3.0: Improved taxonomic sampling, uniform nomenclature of novel conserved microRNA families, and updated covariance models.
Clarke, A. W.; Hoye, E.; Hembrom, A. A.; Paynter, V. M.; Vinther, J.; Wyrozzemski, L.; Biryukova, I.; Formaggioni, A.; Ovchinnikov, V.; Herlyn, H.; Pierce, A.; Wu, C.; Aslanzadeh, M.; Cheneby, J.; Martinez, P.; Friedlander, M. R.; Hovig, E.; Hackenberg, M.; Umu, S. U.; Johansen, M.; Peterson, K. J.; Fromm, B.
10.1101/2024.09.27.615356 — evolutionary biology — Posted on 2024-09-28
325 Less is more: Slow-codon windows enhance eGFP mRNA resilience against RNA interference
Mueller, J. A.; Schwake, G.; Reiser, A.; Woschee, D.; Alirezaeizanjani, Z.; Raedler, J. O.; Rudorf, S.
10.1101/2024.09.27.615338 — biophysics — Posted on 2024-09-28
329 A repository of Ogden syndrome (NAA10) and NAA15 patient derived iPSC lines and isogenic pairs by X-chromosome screening and genome-editing.
Wesely, J.; Rusielewicz, T.; Chen, Y.-r.; Hartley, B.; McKenzie, D.; Yim, M.; Maguire, C. T.; Bia, R.; Franklin, S.; Makwana, R.; Marchi, E.; Nikte, M.; Patil, S.; Sapar, M.; Moroziewicz, D.; Global Stem Cell Array Team, N.; Lee, J.; Monsma, F.; Paull, D.; Lyon, G.
10.1101/2024.09.28.615067 — genetics — Posted on 2024-09-28
337 Potentiation of active locomotor state by spinal-projecting serotonergic neurons
Dasen, J.; Fenstermacher, S.; Dymecki, S.; Chaimowitz, C.; Vonasek, A.; Gattuso, H.; Jessell, T.
10.1101/2024.09.26.615260 — neuroscience — Posted on 2024-09-28
341 Effects of alcohol on the transcriptome, methylome, and metabolome of in vitro gastrulating human embryonic cells
Wallen, E.; Ramo, K.; Vehvilainen, J.; Sokka, J.; Lehtonen, M.; Otonkoski, T.; Trokovic, R.; Auvinen, P.; Karkkainen, O.; Kaminen-Ahola, N.
10.1101/2024.09.26.615159 — genetics — Posted on 2024-09-28
342 Automating an insect biodiversity metric using distributed optical sensors: an evaluation across Kansas, USA cropping systems
Rydhmer, K.; Eckberg, J. O.; Lundgren, J. G.; Jansson, S.; Still, L.; Quinn, J. E.; Washington, R.; Lemmich, J.; Nikolajsen, T.; Sheller, N.; Michels, A. M.; Bredeson, M. M.; Rosenzweig, S. T.; Bick, E. N.
10.1101/2023.08.15.553397 — ecology — Posted on 2024-09-28
343 Integrator complex subunit 12 knockout overcomes a transcriptional block to HIV latency reversal
Gray, C. N.; Ashokkumar, M.; Janssens, D. H.; Kirchherr, J. L.; Allard, B.; Hsieh, E.; Hafer, T. L.; Archin, N. M.; Browne, E. P.; Emerman, M.
10.1101/2024.08.30.610517 — microbiology — Posted on 2024-09-28
346 Structural and functional analysis of cancer-associated missense variants in the retinoblastoma protein (Rb) pocket domain
Castro, A.; Ruiz-Rivera, A.; Moorman, C. C.; Wolf-Saxon, E. R.; Mims, H. N.; Vasquez-Meza, V. I.; Rangel, M. A.; Loera, M. M.; Bond, I.; Buchanan, S. B.; Villarreal, E.; Tripathi, S.; Rubin, S. M.; Burke, J. R.
10.1101/2024.09.22.614354 — biochemistry — Posted on 2024-09-28
348 Abundance and distribution of ringed and bearded seals in the Chukchi Sea: a reference for future trends
Boveng, P. L.; Chernook, V. I.; Moreland, E. E.; Conn, P. B.; Trukhanova, I. S.; Cameron, M. F.; Christman, C. L.; Crawford, J. A.; Harwood, L.; Hou, B. X.; Koslovsky, S. M.; Lindsay, J. M.; Litovka, D. I.; London, J. M.; McClintock, B. T.; Platonov, N.; Quakenbush, L.; Richmond, E. L.; Vasiliev, A.; Von Duyke, A. L.; Willoughby, A.
10.1101/2024.08.27.608330 — ecology — Posted on 2024-09-28
349 The pericardium forms as a distinct structure during heart formation
Moran, H. R.; Nyarko, O. O.; O'Rourke, R.; Ching, R.-C. K.; Riemslagh, F. W.; Pena, B.; Burger, A.; Sucharov, C. C.; Mosimann, C.
10.1101/2024.09.18.613484 — developmental biology — Posted on 2024-09-28
351 Heparan sulphate binding controls in vivo half-life of the HpARI protein family
Colomb, F.; Jamwal, A.; Ogunkanbi, A.; Frangova, T.; Savage, A. R.; Kelly, S.; Wright, G. J.; Higgins, M. K.; McSorley, H. J.
10.1101/2024.05.06.592731 — immunology — Posted on 2024-09-28
352 Audio-visual concert performances synchronize an audience's heart rates
Czepiel, A. M.; Fink, L. K.; Scharinger, M.; Seibert, C.; Wald-Fuhrmann, M.; Kotz, S. A.
10.1101/2024.04.10.588486 — neuroscience — Posted on 2024-09-28
353 Microsaccade Selectivity as Discriminative Feature for Object Decoding
Nouri, S.; Soltani Tehrani, A.; Faridani, N.; Toosi, R.; Noroozi, J.; Dehaqani, M.-R. A.
10.1101/2024.04.13.589338 — neuroscience — Posted on 2024-09-28
354 Transcriptomic landscape of mammalian ventral pallidum at single-cell resolution
Yang, L.; Fang, L. Z.; Lynch, M. R.; Xu, C. S.; Hahm, H.; Zhang, Y.; Heitmeier, M. R.; Costa, V.; Samineni, V. K.; Creed, M. C.
10.1101/2024.05.24.595793 — neuroscience — Posted on 2024-09-28
356 Human skeletal muscle fiber heterogeneity beyond myosin heavy chains
Moreno-Justicia, R.; Van der Stede, T.; Stocks, B.; Laitila, J.; Seaborne, R. A.; Van de Loock, A.; Lievens, E.; Samodova, D.; Marin-Arraiza, L.; Dmytriyeva, O.; Browaeys, R.; Van Vossel, K.; Moesgaard, L.; Yigit, N.; Anckaert, J.; Weyns, A.; Van Thienen, R.; Sahl, R. E.; Zanoteli, E.; Wierer, M.; Mestdagh, P.; Lawlor, M. W.; Vandesompele, J.; Ochala, J.; Hostrup, M.; Derave, W.; Deshmukh, A. S.
10.1101/2023.09.07.556665 — physiology — Posted on 2024-09-28
357 Functional protein mining with conformal guarantees
Boger, R. S.; Chithrananda, S.; Angelopoulos, A. N.; Yoon, P. H.; Jordan, M. I.; Doudna, J. A.
10.1101/2024.06.27.601042 — bioinformatics — Posted on 2024-09-28
363 Discrepancies in readouts between Infinium MethylationEPIC v2.0 and v1.0 reflected in DNA methylation-based tools: implications and considerations for human population epigenetic studies
Zhuang, B. C.; Jude, M. S.; Konwar, C.; Yusupov, N.; Ryan, C. P.; Engelbrecht, H.-R.; Whitehead, J.; Halberstam, A. A.; MacIsaac, J. L.; Dever, K.; Tran, T. K.; Korinek, K.; Zimmer, Z.; Lee, N. R.; McDade, T. W.; Kuzawa, C. W.; Huffman, K. M.; Belsky, D. W.; Binder, E. B.; Czamara, D.; Korthauer, K.; Kobor, M. S.
10.1101/2024.07.02.600461 — genomics — Posted on 2024-09-28
366 Transient Notch Activation Converts Pluripotent Stem Cell-Derived Cardiomyocytes towards a Purkinje Fiber Fate
Gonzalez, D. M.; Dariolli, R.; Moyett, J.; Song, S.; Shewale, B.; Bliley, J. M.; Ma'ayan, A.; Rentschler, S.; Feinberg, A. W.; Sobie, E.; Dubois, N.
10.1101/2024.09.22.614353 — developmental biology — Posted on 2024-09-28
368 Mitotic chromatin marking governs asymmetric segregation of DNA damage
Ferrand, J.; Dabin, J.; Chevallier, O.; Kane-Charvin, M.; Kupai, A.; Hrit, J.; Rothbart, S. B.; Polo, S. E.
10.1101/2023.09.04.556166 — molecular biology — Posted on 2024-09-28
369 Second impact of an acute total body irradiation on thymic epithelial cells
Namiki, K.; Muramatsu, W.; Miyao, T.; Ishii, H.; Endo, R.; Hagiwara, N.; Miyauchi, M.; Yoshida, M.; Akiyama, N.; Akiyama, T.
10.1101/2024.07.30.605780 — immunology — Posted on 2024-09-28
371 A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective and anti-inflammatory properties following status epilepticus in mice
Ferhat, L.; Soussi, R.; Masse, M.; Kyriatzis, G.; Girard, S.; Gassiot, F.; Gaudin, N.; Laurencin, M.; Bernard, A.; Bole, A.; Ferracci, G.; Smirnova, M.; Roman, F.; Dive, V.; Cisternino, S.; Temsamani, J.; David, M.; Lecorche, P.; Jacquot, G.; KHRESTCHATISKY, M.
10.1101/2024.07.15.603208 — neuroscience — Posted on 2024-09-28
372 Like sisters but not twins - vasopressin and oxytocin excite BNST neurons via cell type-specific expression of oxytocin receptor to reduce anxious arousal
Francesconi, W.; Olivera-Pasilio, V.; Berton, F.; Olson, S. L.; Chudoba, R.; Monroy, L. M.; Krabichler, Q.; Grinevich, V.; Dabrowska, J.
10.1101/2024.09.06.611656 — neuroscience — Posted on 2024-09-28
373 NeuroMechFly v2, simulating embodied sensorimotor control in adult Drosophila
Wang-Chen, S.; Stimpfling, V. A.; Lam, T. K. C.; Ozdil, P. G.; Genoud, L.; Hurtak, F.; Ramdya, P.
10.1101/2023.09.18.556649 — neuroscience — Posted on 2024-09-28
374 Explaining tip-of-the-tongue experiences in older adults: contributions of brain function, structure, and perfusion in relation to older adults cardiorespiratory fitness
Rahman, F.; Tsvetanov, K. A.; Feron, J.; Mullinger, K.; Joyce, K.; Gilani, A.; Fernandes, E. G.; Wetterlin, A.; Wheeldon, L. R.; Lucas, S. J. E.; Segaert, K.
10.1101/2023.12.08.570799 — neuroscience — Posted on 2024-09-28
377 Generative machine learning of ADAR substrates for precise and efficient RNA editing
Jiang, Y.; Bagepalli, L. R.; Banjanin, B. S.; Savva, Y. A.; Cao, Y.; Guo, L.; Briggs, A. W.; Booth, B.; Hause, R. J.
10.1101/2024.09.27.613923 — bioengineering — Posted on 2024-09-28
379 Genomic insights into the successful invasion of the avian vampire fly (Philornis downsi) in the Galapagos Islands
Basnet, A.; Palacios, C.; Meng, H.; Nakhwa, D.; Farmer, T.; Dahal, N.; Anchundia, D.; Heimpel, G.; Causton, C.; Koop, J.; Lamichhaney, S.
10.1101/2024.09.26.615210 — evolutionary biology — Posted on 2024-09-28
381 Microbial Metagenomes Across a Complete Phytoplankton Bloom Cycle:High-Resolution Sampling Every 4 Hours Over 22 Days
Nunn, B. L.; Timmins-Schiffman, E.; Mudge, M. C.; Plubell, D.; Chebli, G.; Kubanek, J.; Riffle, M.; Noble, W. S.; Harvey, E.; Nunn, T. A.; Huntemann, ; Clum, ; Foster, ; Roux, ; Palaniappan, ; Mukherjee, ; Reddy, ; Daum, ; Copeland, ; Chen, ; Ivanova, ; Kyrpides, ; Glavina del rio, ; Eloe-Fadrosh,
10.1101/2024.09.27.614549 — ecology — Posted on 2024-09-28
382 Organ-specific electrophile responsivity mappingin live C. elegans
Liu, J.; Kulkarni, A.; Gao, Y.-Q.; Urul, D. A.; Hamelin, R.; Novotny, B. A.; Long, M. J. C.; Aye, Y.
10.1101/2024.09.27.615266 — molecular biology — Posted on 2024-09-28
383 Mapping herpesvirus-driven impacts on the cellular milieu and transcriptional profile of Kaposi sarcoma in patient-derived mouse models
Li, X.; Weaver Ohler, Z.; Day, A.; Bassel, L.; Grosskopf, A.; Afsari, B.; Tagawa, T.; Custer, W.; Mangusan, R.; Lurain, K.; Yarchoan, R.; Ziegelbauer, J.; Ramaswami, R.; Krug, L. T.
10.1101/2024.09.27.615429 — microbiology — Posted on 2024-09-28
384 Charting Cortical-Layer Specific Area Boundaries Using Gibbs Ringing Attenuated T1w/T2w-FLAIR Myelin MRI
Autio, J. A.; Uematsu, A.; Ikeda, T.; Ose, T.; Hou, Y.; Magrou, L.; Kimura, I.; Ohno, M.; Murata, K.; Coalson, T.; Kennedy, H.; Glasser, M. F.; Van Essen, D. C.; Hayashi, T.
10.1101/2024.09.27.615294 — neuroscience — Posted on 2024-09-28
385 HEXIM1 is correlated with Alzheimer's disease pathology and regulates immediate early gene dynamics in neurons
Htet, M.; Estay-Olmos, C.; Hu, L.; Wu, Y.; Powers, B. E.; Campbell, C.; Ahmed, M. R.; Hohman, T. J.; Schneider, J. A.; Bennett, D. A.; Menon, V.; De Jager, P.; Kaas, G. A.; Colbran, R. J.; Greer, C. B.
10.1101/2024.09.27.615234 — neuroscience — Posted on 2024-09-28
387 A Novel Mouse Model Demonstrates In Vivo Replenishment of Central Nervous System Pericytes After Successful Acute Ablation
Atak, D.; Yildiz, E.; Ozkan, E.; Yousefi, M.; Ozkan, A.; Gokyuzu, A. B.; Kizilirmak, A. B.; Alnajjar, I. A.; Kanar, C.; Caan, Z. L.; Zeybek, S. U.; Kucukali, C. I.; Tuzun, E.; Gursoy-Ozdemir, Y.; Vural, A.
10.1101/2024.09.27.614665 — neuroscience — Posted on 2024-09-28
389 Plant Mobile Domain protein-DNA motif modules counteract Polycomb silencing to stabilize gene expression
Pelissier, T.; Jarry, L.; Olivier, M.; Dajoux, G.; Pouch-Pelissier, M.-N.; Courtois, C.; Descombin, J.; Picault, N.; Moissiard, G.; Mathieu, O.
10.1101/2024.09.27.615353 — plant biology — Posted on 2024-09-28
391 The role of ERFVIIs as oxygen-sensing transducers in the evolution of land plant response to hypoxia
Dalle Carbonare, L.; van Veen, H.; Shukla, V.; Perri, M.; Bui, L. T.; Holdsworth, M. J.; Licausi, F.
10.1101/2024.09.27.615240 — plant biology — Posted on 2024-09-28
392 End of preservation normothermic machine perfusion of porcine kidneys after ischaemic injury reprograms metabolism and induces fibrosis after transplant despite unchanged function: insights from the renal proteome.
Mulvey, J. F.; Snashall, C.; Rozenberg, K.; Lo Faro, M. L.; Eijken, M.; Lohmann, S.; Moers, C.; Leuvenink, H.; Baan, C.; Hoogduijn, M.; Keller, A. K.; Sutton, C.; Hunter, J.; Jespersen, B.; Ploeg, R.; Shaheed, S.
10.1101/2024.09.27.615349 — physiology — Posted on 2024-09-28
393 MKK4 and MKK7 control degeneration of retinal ganglion cell somas and axons after glaucoma-relevant injury.
Marola, O. J.; Syc-Mazurek, S. B.; Yablonski, S. E. R.; Shrager, P. G.; John, S. W. M.; Libby, R. T.
10.1101/2024.09.27.614559 — pathology — Posted on 2024-09-28
395 Tumor Cell Spatial Organization Directs EGFR/RAS/RAF Pathway Primary Therapy Resistance through YAP Signaling
Nakagawa, R.; Beardsley, A.; Durney, S.; Hayward, M.-K.; Subramanyam, V.; Meyer, N. P.; Wismer, H.; Goodarzi, H.; Weaver, V. M.; Van de Mark, D.; Goga, A.
10.1101/2024.09.26.615226 — cancer biology — Posted on 2024-09-28
396 Decoding mEos4b Day-Long Maturation and Engineering Fast Maturing Variants
Maity, A.; Glushonkov, O.; Ayala, I.; Tacnet, P.; Wulffele, J.; Frachet, P.; Brutscher, B.; Bourgeois, D.; Adam, V.
10.1101/2024.09.26.615204 — biophysics — Posted on 2024-09-28
399 CAMDA 2023: finding patterns in urban microbiomes
Contreras-Peruyero, H.; Nunez-Morales, I.; Vazquez-Rosas-Landa, M.; Santana-Quinteros, D.; Pashkov, A.; Carranza-Barragan, M. E.; Perez-Estrada, R.; Guerrero-Flores, S.; Balanzario, E.; Muniz Sanchez, V.; Nakamura, M.; Ramirez-Ramirez, L. L.; Selem-Mojica, N.
10.1101/2024.09.26.614772 — bioinformatics — Posted on 2024-09-28
405 Recurrent introgression and geographical stratification shape Saccharomyces cerevisiae in the Neotropics
Avelar-Rivas, J. A.; Sedeno, I.; Garcia-Ortega, L. F.; Urban Aragon, J. A.; Mancera, E.; DeLuna, A.; Morales, L.
10.1101/2024.09.27.615306 — evolutionary biology — Posted on 2024-09-28
407 Terrestrial herbivory drives adaptive evolution in an aquatic community via indirect effects
Schaefer, M.; Malacrino, A.; Walcher, C.; Spaak, P.; Serwaty-Sarazov, M.; Kaeser, S.; Bulas, T.; Boesch, C.; Dexter, E.; Hottinger, J.; Boettner, L.; Vorburger, C.; Ebert, D.; Xu, S.
10.1101/2024.09.27.615417 — evolutionary biology — Posted on 2024-09-28
408 Characterizing the soil microbial community associated with the fungal pathogen Coccidioides immitis
Radosevich, M. T.; Head, J. R.; Couper, L.; Weaver, A. K.; Camponuri, S. K.; Montoya, L.; Taylor, J.; Remais, J. V.
10.1101/2024.09.27.615053 — ecology — Posted on 2024-09-28
411 Comparative evaluation of cell-based assay technologies for scoring drug-induced condensation of SARS-CoV-2 nucleocapsid protein
Quek, R. T.; Shirazinejad, C. R.; Young, C. L.; Hardy, K. S.; Lim, S.; Elms, P. J.; McSwiggen, D. T.; Mitchison, T. J.; Silver, P. A.
10.1101/2024.09.26.615262 — molecular biology — Posted on 2024-09-28
412 Detection of bacteria through taste receptors primes the cellular immune response
Mazariegos, A. N.; Maniere, G.; Camp, D.; Khaul, R.; Duval, C. J.; Milleville, R.; Berthelot-Grosjean, M.; Alves, G.; Royet, J.; Grosjean, Y.; Musso, P.-y.; Tanentzapf, G.
10.1101/2024.09.26.615243 — immunology — Posted on 2024-09-28
414 Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis
Hakim, S. E.; Choudhary, N.; Malhotra, K.; Peng, J.; Arafa, A.; Bültemeier, A.; Friedhoff, R.; Bauer, M.; Witte, C.-P.; Herde, M.; Heretsch, P.; Pucker, B.; Franke, J.
10.1101/2024.09.27.614867 — plant biology — Posted on 2024-09-28
415 Asymptomatic infection and antibody prevalence to co-occurring avian influenza viruses vary substantially between sympatric seabird species following H5N1 outbreaks
Greco, F.; Ravenswater, H. M.; Ruiz-Raya, F.; D'Avino, C.; Newell, M. A.; Hewitt, J.; Taylor, E.; Benninghaus, E.; Daunt, F.; Goodman, G.; Steel, D.; Park, J.; Philip, E.; Thomas, S.; Slomka, M. J.; Falchieri, M.; Reid, S. M.; James, J.; Banyard, A. C.; Burthe, S. J.; Cunningham, E. J. A.
10.1101/2024.09.26.614314 — ecology — Posted on 2024-09-27
417 The essential kinase TgGSK regulates centrosome division and endodyogeny in Toxoplasma gondii
Krueger, A.; Horjales, S.; Yang, C.; Blakely, W. J.; Francia, M. E.; Arrizabalaga, G.
10.1101/2024.09.27.615374 — microbiology — Posted on 2024-09-27
421 HU promotes higher-order chromosome organisation and influences DNA replication rates in Streptococcus pneumoniae
Mazzuoli, M.-V.; van Raaphorst, R.; Martin, L.; Bock, F. P.; Thierry, A.; Marbouty, M.; Waclawikova, B.; Stinenbosch, J.; Koszul, R.; Veening, J.-W.
10.1101/2024.09.27.615122 — microbiology — Posted on 2024-09-27
423 First report of pathogenic Leptospira in Sri Lankan bats: A potential reservoir risk
Perera, T.; Schwarz, F.; Muzeniek, T.; Siriwardana, S.; Becker-Ziaja, B.; Perera, I.; Handunnetti, S.; Weerasena, J.; Premawansa, G.; Premawansa, S.; Yapa, W.; Kohl, C.; Nitsche, A.
10.1101/2024.09.27.615370 — microbiology — Posted on 2024-09-27
424 Entorhinal grid-like codes for visual space during memory formation
Graichen, L. P.; Linder, M. S.; Keuter, L.; Jensen, O.; Doeller, C. F.; Lamm, C.; Staudigl, T.; Wagner, I. C.
10.1101/2024.09.27.615339 — neuroscience — Posted on 2024-09-27
425 Predictive influences on memory encoding: investigating oscillations and the N400 event-related potential component
Jano, S. L.; Schlesewsky, M.; Chatburn, A.; Coussens, S.; Cross, Z. R.; Bornkessel-Schlesewsky, I.
10.1101/2024.09.27.615404 — neuroscience — Posted on 2024-09-27
427 The Neural Blueprint of Stress Susceptibility: Brain-wide neuronal activity associated with the consequences of stress
Dirven, B. C. J.; Negwer, M.; Botan, A.; Maas, R.; van Melis, L.; Merjenburgh, S.; van Rijn, R.; Grandjean, J.; Homberg, J.; Kozicz, T.; Henckens, M. J. A. G.
10.1101/2024.09.27.615412 — neuroscience — Posted on 2024-09-27
430 Impaired excitability of fast-spiking neurons in a novel mouse model of KCNC1 epileptic encephalopathy
Wengert, E. R.; Cheng, M. A.; Liebergall, S. R.; Markwalter, K. H.; Hong, Y.; Arias, L.; Marsh, E. D.; Zhang, X.; Somarowthu, A.; Goldberg, E. M.
10.1101/2024.09.27.615463 — neuroscience — Posted on 2024-09-27
431 Purkinje cell intrinsic activity shapes cerebellar development and function
Osorio, C.; White, J. J.; Torrents Sole, P.; Mandemaker, N.; Olivero, F.; Kirwan, F.; de Winter, F.; Regolo, E.; Romana Fiocchi, F.; Serra, I.; Tjon, S.; Ozgur, Z.; van den Hout, M. C. G. N.; van Ijcken, W. F. J.; Lopez-Bendito, G.; Badura, A.; Lim, L.; van Woerden, G.; Schonewille, M.
10.1101/2024.09.27.615345 — neuroscience — Posted on 2024-09-27
436 Mapping the landscape of social behavior
Klibaite, U.; Li, T.; Aldarondo, D.; Akoad, J.; Ölveczky, B.; Dunn, T. W.
10.1101/2024.09.27.615451 — animal behavior and cognition — Posted on 2024-09-27
437 The snoRNP chaperone snR190 and the Npa1 complex form a macromomecular assembly required for 60S ribosomal subunit maturation
Hamze, H.; Jaafar, M.; Khreiss, A.; Dominique, C.; Bourdeaux, J.; Mendez-Godoy, A.; Kressler, D.; Humbert, O.; Albert, B.; Henras, A. K.; HENRY, Y.
10.1101/2024.09.27.614885 — molecular biology — Posted on 2024-09-27
439 Structure-guided design, synthesis, and characterization of C22- and C32-modified FK520 analogs with enhanced activity against human pathogenic fungi
Dome, P. A.; Jeong, P.; Nam, G.; Jang, H.; Rivera, A.; Averette, A. F.; Park, E.; Liao, T.-C.; Ciofani, M.; Wu, J.; Chi, J.-T. A.; Venters, R. A.; Park, H.-J.; Steinbach, W. J.; Juvvadi, P. R.; Heitman, J.; Hong, J.
10.1101/2024.09.27.615491 — microbiology — Posted on 2024-09-27
441 The Haemagglutinin Gene of Bovine Origin H5N1 Influenza Viruses Currently Retains an Avian Influenza Virus phenotype.
Yang, J.; Qureshi, M.; Kolli, B. R.; Peacock, T. P.; Sadeyen, J.-R.; Carter, T.; Richardson, S.; Daines, R.; Barclay, W. S.; Brown, I. H.; Iqbal, M.
10.1101/2024.09.27.615407 — microbiology — Posted on 2024-09-27
442 Evaluation of the antimicrobial activity of the alcoholic extract of Tagetes erecta against bacteria and fungi of clinical importance.
Martinez Gonzalez, G.; Suarez Gonzalez, F.; Chavez Alanuza, A.; Cuarto Hernandez, A. G.; Montes de Oca Cuenca, S. S.; de Jesus Olvera, L.; Almeida Villegas, J. A.
10.1101/2024.09.27.615189 — microbiology — Posted on 2024-09-27
444 The usual and unusual functions of thioredoxins in the metabolism and stress-response of sulfate-reducing bacteria
Majumder, E. L.- W.; Hou, L.; Fitriasari, S.; Whittle, F. B.; Trotter, V. V.; Butland, G.; Petzold, C. J.; Wall, J. D.
10.1101/2024.09.27.615472 — microbiology — Posted on 2024-09-27
445 Mycobacterium tuberculosis overcomes phosphate starvation by extensively remodelling its lipidome with phosphorus-free lipids
Gray, R. M.; Hunt, D. M.; Silva dos Santos, M.; Liu, J.; Agapova, A.; Rodgers, A.; Garza-Garcia, A.; MacRae, J. I.; Gutierrez, M. G.; Lee, R.; Carvalho, L. P.
10.1101/2024.09.27.615480 — microbiology — Posted on 2024-09-27
446 TvAP65 in Trichomonas vaginalis Promotes HPV Infection by Interacting with Host Molecules
Mei, X.; Sheng, W.; Zhang, Y.; Tian, W.; Tian, X.; Yang, Z.; Wang, S.; Zhang, Z.
10.1101/2024.09.27.615334 — microbiology — Posted on 2024-09-27
451 Climatic fluctuations modulate eco-evolutionary processes associated with pathogen dynamics and continue to fuel bacterial spot epidemics in tomato
Bhandari, R.; Kaur, A.; Russell, I.; Romanus, O. M.; Brokaw, D.; Keinath, A. P.; Snipes, Z.; Rollins, P.; Baugher, N.; Meadows, I.; Torrance, T. N.; Dutta, B.; Sikora, E.; Molinari, R.; Soubeyrand, S.; Potnis, N.
10.1101/2024.09.27.615185 — microbiology — Posted on 2024-09-27
452 Insertion of fluorescent proteins near the plug domain of MotB generates functional stator complex.
Gurung, J. P.; Ridone, P.; Biquet-Bisquert, A.; Bryant, G.; Pedaci, F.; Nord, A.; Baker, M. A.
10.1101/2024.09.27.615325 — microbiology — Posted on 2024-09-27
454 Expanding the CRISPR toolbox by engineering Cas12a orthologs of metagenomic discovery
Tao, D.; Xu, B.; Li, S.; Liu, H.; Shi, S.; Wang, Y.; Zhao, C.; Ruan, J.; Fu, L.; Huang, X.; Li, X.; Zhao, S.; Xie, S.
10.1101/2024.09.27.615316 — synthetic biology — Posted on 2024-09-27
455 Tumor microenvironment governs the prognostic landscape of immunotherapy for head and neck squamous cell carcinoma: A computational model-guided analysis
Bhattacharya, P.; Linnenbach, A.; South, A. P.; Martinez-Outschoorn, U.; Curry, J. M.; Johnson, J. M.; Harshyne, L. A.; Mahoney, M. G.; Luginbuhl, A. J.; Vadigepalli, R.
10.1101/2024.09.26.615149 — cancer biology — Posted on 2024-09-27
458 Altered mRNA transport and local translation in iNeurons with RNA binding protein knockdown
Dargan, R. L.; Mikheenko, A.; Johnson, N. L.; Packer, B.; Li, Z.; Craig, E. J.; Sarbanes, S. L.; Bereda, C.; Mehta, P. R.; Keuss, M. J.; Nalls, M. A.; Qi, Y. A.; Weller, C. A.; Fratta, P.; Ryan, V. H.
10.1101/2024.09.26.615153 — neuroscience — Posted on 2024-09-27
460 Endocrine persistence in ER+ breast cancer is accompanied by metabolic vulnerability in oxidative phosphorylation
Tau, S.; Chamberlin, M. D.; Yang, H.; Marotti, J. D.; Roberts, A. M.; Carmichael, M. M.; Cressey, L.; Dragnev, C. P.; Demidenko, E.; Hampsch, R. A.; Soucy, S. M.; Kolling, F. W.; Samkoe, K. S.; Alvarez, J. V.; Kettenbach, A.; Miller, T. W.
10.1101/2024.09.26.615177 — cancer biology — Posted on 2024-09-27
463 Incorporating gene expression and environment improves genomic prediction of wheat traits
Liu, J.; Gock, A.; Ramm, K.; Stops, S.; Phongkham, T.; Norman, A.; Eastwood, R.; Stone, E.; Dillon, S.
10.1101/2024.09.26.612369 — genomics — Posted on 2024-09-27
466 Transcripts with high distal heritability mediate genetic effects on complex metabolic traits
Tyler, A. L.; Mahoney, J. M.; Keller, M. P.; Baker, C.; Gaca, M.; Srivastava, A.; Gerdes Gyuricza, I.; Braun, M. J.; Rosenthal, N.; Attie, A. D.; Churchill, G. A.; Carter, G. W.
10.1101/2024.09.26.613931 — genetics — Posted on 2024-09-27
468 A long-term ecological research data set from the marine genetic monitoring programme ARMS-MBON 2018-2020
Daraghmeh, N.; Exter, K.; Pagnier, J.; Balazy, P.; Cancio, I.; Chatzigeorgiou, G.; Chatzinikolaou, E.; Chelchowski, M.; Chrismas, N. A. M.; Comtet, T.; Dailianis, T.; Deneudt, K.; Diaz de Cerio, O.; Digenis, M.; Gerovasileiou, V.; Gonzalez, J.; Kauppi, L.; Kristoffersen, J. B.; Kuklinski, P.; Lasota, R.; Levy, L.; Malachowicz, M.; Mavric, B.; Mortelmans, J.; Paredes, E.; Pocwierz-Kotus, A.; Reiss, H.; Santi, I.; Sarafidou, G.; Skouradakis, G.; Solbakken, J.; Staehr, P. A. U.; Tajadura, J.; Thyrring, J.; Troncoso, J. S.; Vernadou, E.; Viard, F.; Zafeiropoulos, H.; Zbawicka, M.; Pavloudi, C.; Ob
10.1101/2024.09.26.614897 — ecology — Posted on 2024-09-27
473 Undoing of firing rate adaptation enables invariant population codes
Brandao, S. C.; Ramirez, L.; Walter, A. M.; Silies, M.; Martelli, C.
10.1101/2024.09.26.614457 — neuroscience — Posted on 2024-09-27
477 Ultra-Fast Multi-Organ Proteomics Unveils Tissue-Specific Mechanisms of Drug Efficacy and Toxicity
Xiong, Y.; Tan, L.; Chan, W.-k.; Yin, E.; Donepudi, S. R.; Ding, J.; Wei, B.; Tran, B.; Martinez, S.; Mahmud, I.; Stewart, H.; Hermanson, D.; Weinstein, J. N.; Lorenzi, P. L.
10.1101/2024.09.25.615060 — systems biology — Posted on 2024-09-27
482 Characterisation of virulence of Puccinia coronata f. sp. avenae in Australia in the 2023 growing season
Nguyen, D. T.; Henningsen, E.; Lewis, D. C.; Mago, R.; Sperschneider, J.; Stone, E.; Dodds, P.; Figueroa, M.
10.1101/2024.09.25.614061 — plant biology — Posted on 2024-09-27
484 MALT1 protease inhibition restrains glioblastoma progression by reversing tumor-associated macrophage-dependent immunosuppression
Hofstatter Azambuja, J.; Yerneni, S. S.; Maurer, L. M.; Crentsil, H. E.; Debom, G. N.; Klei, L.; Smyers, M.; Sneiderman, C. T.; Schwab, K. E.; Acharya, R.; Lin Wu, Y.; Ekambaram, P.; Hu, D.; Gough, P. J.; Bertin, J.; Melnick, A.; Kohanbash, G.; Bao, R.; Lucas, P. C.; McAllister-Lucas, L. M.
10.1101/2024.09.26.614808 — cancer biology — Posted on 2024-09-27
486 Single-cell Transcriptome Profiling of Post-treatment and Treatment-naive Colorectal Cancer: Insights into Putative Mechanisms of Chemoresistance
Puzanov, G. A.; Astier, C.; Yurchenko, A. A.; Jules-Clement, G.; Andre, F.; Marabelle, A.; Hollebecque, A.; Nikolaev, S. I.
10.1101/2024.09.26.614712 — cancer biology — Posted on 2024-09-27
487 Pancreatic cancer cells overexpressing interleukin 6 induce T-cell-mediated tumor clearance and durable anti-tumor immune response
Arneson-Wissink, P. C.; Bartlett, A. Q.; Mendez, H.; Zhu, X.; Dickie, J.; McWhorter, M.; Levasseur, P. R.; Diba, P.; Byrne, K.; Scott, G. D.; Eil, R.; Grossberg, A.
10.1101/2024.09.26.615308 — cancer biology — Posted on 2024-09-27
489 Lumen charge governs ion transport in β-barrel nanopores
Mayer, S. F.; Mitsioni, M.; van den Heuvel, L.; Robin, P.; Ronceray, N.; Marcaida, M. J.; Abriata, L. A.; Krapp, L. F.; Anton, J. S.; Soussou, S.; Jeanneret-Grosjean, J.; Fulciniti, A.; Moller, A.; Vacle, S.; Feletti, L.; Brinkerhoff, H.; Laszlo, A. H.; Gundlach, J. H.; Emmerich, T.; Dal Peraro, M.; Radenovic, A.
10.1101/2024.09.26.615172 — biophysics — Posted on 2024-09-27
490 Bimodal cell mass distribution separates CD8+ T cells into two distinct types with divergentdifferentiation dynamics
Yu, J.; Zhang, Y.; Duquette, S. M.; Yee, G. L.; Dinter, T.; Usherwood, T. R.; Wu, W.; Miettinen, T.; Spranger, S.; Manalis, S. R.
10.1101/2024.09.26.615179 — biophysics — Posted on 2024-09-27
492 Unipept 6.0: Expanding metaproteomics analysis with support for missed cleavages, semi-tryptic and non-tryptic peptides
Vande Moortele, T.; Devlaminck, B.; Van de Vyver, S.; Van Den Bossche, T.; Martens, L.; Dawyndt, P.; Mesuere, B.; Verschaffelt, P.
10.1101/2024.09.26.615136 — bioinformatics — Posted on 2024-09-27
493 Multi-View Integrative Approach For Imputing Short-Chain Fatty Acids and Identifying Key factors predicting Blood SCFA
Liu, A.; Tian, B.; Qiu, C.; Su, K.; Jiang, L.; Zhao, C.; Song, M.; Liu, Y.; Qu, G.; Zhou, Z.; Zhang, X.; Mungasavalli Gnanesh, S. S.; Thumbigere Math, V.; Luo, Z.; Tian, Q.; Zhang, L.-S.; Wu, C.; Ding, Z.; Shen, H.; Deng, H.-W.
10.1101/2024.09.25.614767 — bioinformatics — Posted on 2024-09-27
494 FishCODE: a web-based information platform for comprehensive omics data exploration in fish research
Li, H.; Zhang, W.; Ren, K.; Yang, H.; Zhang, L.; Younas, W.; Cheng, Y.; Wang, Y.; Shi, M.; Xia, X.-Q.
10.1101/2024.09.25.614839 — bioinformatics — Posted on 2024-09-27
498 Discovery of electrophilic degraders that exploit SNAr chemistry
Zhuang, Z.; Byun, W. S.; Kozicka, Z.; Dwyer, B. G.; Donovan, K. A.; Jiang, Z.; Jones, H. M.; Abeja, D. M.; Nix, M. N.; Zhong, J.; Slabicki, M.; Fischer, E. S.; Ebert, B. L.; Gray, N. S.
10.1101/2024.09.25.615094 — biochemistry — Posted on 2024-09-27
500 Identification of Human Pathways Acting on Nuclear Non-Coding RNAs Using the Mirror Forward Genetic Approach
Che, R.; Panah, M.; Mirani, B.; Knowles, K.; Ostapovich, A.; Majumdar, D.; Chen, X.; DeSimone, J.; White, W.; Noonan, M.; Luo, H.; Alexandrov, A.
10.1101/2024.09.26.615073 — genetics — Posted on 2024-09-27
502 Transcriptome and evolutionary analysis of Pseudotrichomonas keilini, a free-living anaerobic eukaryote
Abu-Elmakarem, H.; Taerum, S. J.; Petitjean, C.; Kotyk, M.; Kay, C.; Cepicka, I.; Bass, D.; Gile, G. H.; Williams, T. A.
10.1101/2024.09.26.614816 — evolutionary biology — Posted on 2024-09-27
505 Making the Monitoring Framework of the Kunming-Montreal Global Biodiversity Framework fit for purpose.
Affinito, F.; Butchart, S. H. M.; Nicholson, E.; Hirsch, T.; Williams, J. M.; Campbell, J. E.; Ferrari, M. F.; Gabay, M.; Gorini, L.; Kalamujic Stroil, B.; Kohsaka, R.; Painter, B.; Pinto, J. C.; Scholz, A. H.; Straza, T. R. H.; Tshidada, N.; Vallecillo, S.; Widdicombe, S.; Gonzalez, A.
10.1101/2024.09.25.614896 — ecology — Posted on 2024-09-27
507 Increases in Arctic extreme climatic events are linked to negative fitness effects on the local biota
Lemaire, M. C.; Bokhorst, S.; Witheford, A. J.; Macias-Fauria, M.; Salguero-Gomez, R.
10.1101/2024.09.26.615176 — ecology — Posted on 2024-09-27
508 Different signaling interpretations by PKC eta and theta control T cell function and exhaustion
Mann, T. H.; Knox, H. M.; Ma, S.; Furgiuele, J.; Globig, A.-M.; LaPorta, M.; Chung, H. K.; McDonald, B.; Ghassemian, M.; Zhao, S.; Tseng, H.; Farsakoglu, Y.; Tripple, V.; Koo, J.; Newton, A. C.; Kaech, S. M.
10.1101/2024.09.26.615103 — immunology — Posted on 2024-09-27
511 Adaptation of retinal discriminability to natural scenes
Ding, X.; Lee, D.; Melander, J. B.; Ganguli, S.; Baccus, S. A.
10.1101/2024.09.26.615305 — neuroscience — Posted on 2024-09-27
513 Adult choline supplementation in a Down syndrome model reduces co-morbidities and improves cognition
Tallino, S.; Etebari, R.; McDonough, I.; Leon, H.; Sepulveda, I.; Winslow, W.; Bartholomew, S. K.; Perez, S.; Mufson, E. J.; Velazquez, R.
10.1101/2024.09.26.615088 — neuroscience — Posted on 2024-09-27
517 Interpreting Sleep Activity Through Neural Contrastive Learning
Chen, Z.; Zheng, H.; Zhou, J.; Zheng, L.; Lin, P.; Wang, H.; Dolan, R. J.; Behrens, T. E.; Liu, Y.
10.1101/2024.09.25.615100 — neuroscience — Posted on 2024-09-27
518 Dysregulation of the fluid homeostasis system by aging
Jang, H.; Behne Sharma, A.; Dan, U.; Wong, J. H.; Knight, Z. A.; Garrison, J. L.
10.1101/2024.09.26.615271 — neuroscience — Posted on 2024-09-27
521 Skeletal Metastasis of Prostate Cancer Is Augmented by Activation of EphA2 Noncanonical Signaling and Ligand-Deficient Bone Microenvironment
Wang, B.; Lingerak, R.; Petty, A.; Shi, X.; Kim, S.; Lin, H.; Hsieh, J.-T.; Tang, D.; Stiles, B.; Wald, D.; Varambally, S.; Chinnaiyan, A. M.; Lee, Z.; Morrissey, C.
10.1101/2024.09.25.615079 — cancer biology — Posted on 2024-09-27
524 The translation inhibitors kasugamycin, edeine and GE81112 target distinct steps during 30S initiation complex formation
Safdari, H. A.; Morici, M.; Sanchez-Castro, A.; Dallape, A.; Paternoga, H.; Giuliodori, A. M.; Fabbretti, A.; Milon, P.; Wilson, D. N.
10.1101/2024.09.26.614307 — biochemistry — Posted on 2024-09-27
529 Mapping the aggregate g-ratio of white matter tracts using multi-modal MRI
Lu, W. D.; Nelson, M. C.; Leppert, I. R.; Campbell, J. S. W.; Schiavi, S.; Pike, G. B.; Rowley, C. D.; Daducci, A.; Tardif, C. L.
10.1101/2024.09.25.614579 — neuroscience — Posted on 2024-09-27
532 Gestational arsenite exposure alters maternal postpartum heart size and induces Ca2+ handling dysregulation in cardiomyocytes
Taube, N.; Steiner, M.; Ebenebe-Kasonde, O. V.; Kabir, R.; Garbus-Grant, H.; Alam El Din, S.-M.; Illingworth, E.; Wang, N.; Lin, B. L.; Kohr, M. J.
10.1101/2024.09.25.615085 — pharmacology and toxicology — Posted on 2024-09-27
533 Somatic mtDNA Mutation Burden Shapes Metabolic Plasticity in Leukemogenesis
Li-Harms, X.; Lu, J.; Fukuda, Y.; Lynch, J.; Sheth, A.; Pareek, G.; Kaminski, M.; Ross, H. R.; Wright, C. W.; Wu, H.; Wang, Y.-D.; Neal, G.; Ward, A.; Vogel, P.; Pounds, S.; Schuetz, J.; Ni, M.; Kundu, M.
10.1101/2024.09.25.615001 — cancer biology — Posted on 2024-09-27
534 Multimodal Spatial Profiling Reveals Immune Suppression and Microenvironment Remodeling in Fallopian Tube Precursors to High-Grade Serous Ovarian Carcinoma
Kader, T.; Lin, J.-R.; Hug, C.; Coy, S.; Chen, Y.-A.; de Bruijn, I.; Shih, N.; Jung, E.; Pelletier, R. J.; Leon, M. L.; Mingo, G.; Omran, D. K.; Lee, J. S.; Yapp, C.; Satravada, B. A.; Kundra, R.; Xu, Y.; Chan, S.; Tefft, J.; Muhlich, J. L.; Kim, S.; Gysler, S. M.; Agudo, J.; Heath, J. R.; Schultz, N.; Drescher, C.; Sorger, P. K.; Drapkin, R.; Santagata, S.
10.1101/2024.09.25.615007 — cancer biology — Posted on 2024-09-27
535 Trem2 deficiency attenuates breast cancer tumor growth in lean, but not obese or weight loss, mice and is associated with alterations of clonal T cell populations
Pierro, E. W.; Cottam, M. A.; An, H.; Lehmann, B. D.; Pietenpol, J. A.; Wellen, K. E.; Makowski, L.; Rathmell, J. C.; Fingleton, B.; Hasty, A. H.
10.1101/2024.09.25.614811 — cancer biology — Posted on 2024-09-27
537 Lipophilic molecular rotor to assess the viscosity of oil core in nano-emulsion droplets
Elhassan, M.; Faivre, C.; Anton, H.; Conzatti, G.; Didier, P.; Elamin, A. S.; Collot, M.; Anton, N.
10.1101/2024.09.25.614997 — biophysics — Posted on 2024-09-27
539 AnalyzAIRR: A user-friendly guided workflow for AIRR data analysis
Mhanna, V.; Pires, G.; Bohl-Viallefond, G.; El Soufi, K.; Tchitcheck, N.; Klatzmann, D.; Six, A.; Pham, H. P.; Mariotti-Ferrandiz, E.
10.1101/2024.09.25.614939 — bioinformatics — Posted on 2024-09-27
543 Controlled release of microorganisms from engineered living materials
Kalairaj, M. S.; George, I.; George, S. M.; Farfan, S. E.; Lee, Y. J.; Rivera-Tarazona, L. K.; Wang, S.; Abdelrahman, M. K.; Tasmim, S.; Dana, A.; Zimmern, P. E.; Subashchandrabose, S.; Ware, T. H.
10.1101/2024.09.25.615042 — bioengineering — Posted on 2024-09-27
545 Rewilding alters mouse epigenetic aging
Zipple, M. N.; Zhao, I.; Kuo, D. C.; Lee, S. M.; Sheehan, M. J.; Zhou, W.
10.1101/2024.09.25.615023 — genomics — Posted on 2024-09-27
547 Museomics analyses inform about Channichthys icefish species diversity
Garmann-Aarhus, B.; Nikolaeva, E.; Desvignes, T.; Straube, N.; Matschiner, M.
10.1101/2024.09.25.615019 — evolutionary biology — Posted on 2024-09-27
550 Ecological dynamics explain modular denitrification in the ocean
Sun, X.; Buchanan, P.; Zhang, I.; San Roman, M.; Babbin, A. R.; Zakem, E.
10.1101/2024.09.25.615058 — ecology — Posted on 2024-09-27
551 Testing for heavy metals in drinking water collected from Dog Aging Project participants
Sexton, C.; O'Brien, J.; Lytle, J.; Rodgers, S.; Keyser, A.; Kauffman, M.; Dunbar, M.; Dog Aging Project Consortium, ; Edwards, M.; Krometis, L. A.; Ruple, A.
10.1101/2024.09.25.615013 — ecology — Posted on 2024-09-27
553 Differential responses and recovery dynamics of HSPC populations following Plasmodium chabaudi infection.
Bruno, F.; Georgiou, C.; Cunningham, D.; Atkinson, S.; Bett, L.; Secchi, M.; Birch, F.; Gonzalez Anton, S.; langhorne, j.; Lo Celso, C. L.
10.1101/2024.09.25.614952 — developmental biology — Posted on 2024-09-27
556 Challenges and advances for huntingtin detection in cerebrospinal fluid: in support of relative quantification
Harding, R. J.; Xie, Y.; Caron, N. S. J.; Findlay-Black, H.; Lyu, C.; Potluri, N.; Chandrasekaran, R.; Hayden, M. R.; Leavitt, B. R.; Langbehn, D.; Southwell, A.
10.1101/2024.09.25.614766 — neuroscience — Posted on 2024-09-27
557 Oscillatory dynamics of sustained attention states
Solis-Vivanco, R.; Barne, L. C.; Harris, A. M.; Liu, X.; Lavie, N.
10.1101/2024.09.25.614991 — neuroscience — Posted on 2024-09-27
558 Multiplatform lipid analysis of the brain of aging mice by mass spectrometry
Panda, P.; Ferreira, C. R.; Cooper, B. R.; Schaser, A. J.; Aryal, U. K.
10.1101/2024.09.25.614823 — neuroscience — Posted on 2024-09-27
559 Foundry-fabricated dual-color nanophotonic neural probes for photostimulation and electrophysiological recording
Roszko, D. A.; Chen, F.-D.; Straguzzi, J.; Wahn, H.; Xu, A.; McLaughlin, B.; Yin, X.; Chua, H.; Luo, X.; Lo, G.-Q.; Siegle, J. H.; Poon, J. K. S.; Sacher, W. D.
10.1101/2024.09.25.614961 — neuroscience — Posted on 2024-09-27
562 Disarming emotional memories using Targeted Memory Reactivation during Rapid Eye Movement sleep
Greco, V.; Foldes, T.; Harrison, N. A.; Murphey, K.; Wawrzuta, M.; Abdellahi, M. E. A.; Lewis, P. A.
10.1101/2024.09.25.614960 — neuroscience — Posted on 2024-09-27
563 Morning Engagement of Hepatic Insulin Receptors Improves Afternoon Hepatic Glucose Disposal and Storage
Waterman, H. L.; Moore, M. C.; Smith, M.; Farmer, B.; Yankey, K.; Scott, M.; Edgerton, D. S.; Cherrington, A. D.
10.1101/2024.09.25.614969 — physiology — Posted on 2024-09-27
570 CLYBL averts methylmalonyl-CoA mutase inhibition and loss of vitamin B12 by eliminating malyl-CoA
Griffith, C. M.; Conrotte, J.-F.; Paydar, P.; Xie, X.; Heins Marroquin, U.; Gavotto, F. M.; Jäger, C.; Ellens, K. W.; Linster, C. L.
10.1101/2024.09.25.614871 — biochemistry — Posted on 2024-09-27
573 Repeated low-intensity focused ultrasound led to microglial profile changes at long term in TgF344-AD rats
Abjean, L.; Novell, A.; Larrat, B.; Gueorguiev, B. R.; Cailly, T.; Fossey, C.; Fabis, F.; Salomir, R.; Tsartsalis, S.; Tournier, B. B.; Millet, P.; Ceyzeriat, K.
10.1101/2024.09.25.614692 — neuroscience — Posted on 2024-09-27
579 PTEN neddylation aggravates CDK4/6 inhibitor resistance in breast cancer
Liu, F.; Liu, W.; Tan, Y.; Shang, Y.; Ling, S.; Jiang, X.; Zhang, Z.; Sun, S.; Xie, P.
10.1101/2024.08.06.606911 — cell biology — Posted on 2024-09-27
581 Cyclin-dependent kinase 5 (Cdk5) activity is modulated by light and gates rapid phase shifts of the circadian clock
Brenna, A.; Borsa, M.; Saro, G.; Ripperger, J. A.; Glauser, D. A.; Yang, Z.; Adamantidis, A.; Albrecht, U.
10.1101/2024.02.08.579499 — neuroscience — Posted on 2024-09-27
583 Spinal neuron diversity scales exponentially with swim-to-limb transformation during frog metamorphosis
Vijatovic, D.; Toma, F. A.; Harrington, Z. P. M.; Sommer, C.; Hauschild, R.; Trevisan, A. J.; Chapman, P.; Julseth, M. J.; Brenner-Morton, S.; Gabitto, M. I.; Dasen, J. S.; Bikoff, J. B.; Sweeney, L. B.
10.1101/2024.09.20.614050 — neuroscience — Posted on 2024-09-27
584 Causality Mapping Using Resting-state fMRI Reveals Hyperactivity and Hypoconnectivity in Schizophrenia Patients
Tahir, A.; Abdullah, W.; Azeem, W. u.; Khalid, M. F.; Abualait, T.; Shakil, S.; Ahmed, F.; Bashir, S.; Chaudhary, S. U.
10.1101/2024.09.25.614909 — neuroscience — Posted on 2024-09-27
586 CCR5 antagonists as neuroprotective and stroke recovery enhancing agents: a preclinical systematic review and meta-analysis
Sharif, A.; Jeffers, M. S.; Fergusson, D. A.; Bapuji, R.; Nicholls, S. G.; Humphrey, J.; Johnston, W.; Mitchell, E.; Speirs, M.-A.; Stronghill, L.; Vuckovic, M.; Wulf, S.; Shorr, R.; Dowlatshahi, D.; Corbett, D.; Lalu, M. M.
10.1101/2024.09.25.614925 — neuroscience — Posted on 2024-09-27
587 The mitochondrial orf125 affects male fertility of Solanum tuberosum (+) S. commersonii somatic hybrids and participates in the onset of ''Tuberosum''-Type CMS and evolution of common potato
Tamburino, R.; D'Agostino, N.; Aufiero, G.; Nicolia, A.; Facchiano, A.; Giordano, D.; Sannino, L.; Paparo, R.; Arimura, S.-i.; Scotti, N.; Cardi, T.
10.1101/2024.09.25.614866 — plant biology — Posted on 2024-09-27
588 Multi-behavioral phenotyping in zebrafish identifies a novel disruptor of non-associative learning with environmental and human relevance
Leuthold, D.; Herold, N. K.; Nerlich, J.; Bartmann, K.; Scharkin, I.; Hallermann, S. J.; Schweiger, N.; Fritsche, E.; Tal, T.
10.1101/2024.09.25.613874 — pharmacology and toxicology — Posted on 2024-09-27
589 Renal Proximal Tubule Cell-specific Megalin Deletion Does Not Affect Atherosclerosis But Induces Tubulointerstitial Nephritis in Mice Fed Western Diet
Amioka, N.; Franklin, M. K.; Kukida, M.; Zhu, L.; Moorleghen, J. J.; Howatt, D. A.; Katsumata, Y.; Mullick, A. E.; Yanagita, M.; Martinez-Irizarry, M.; Sandoval, R. M.; Dunn, K. W.; Sawada, H.; Daugherty, A.; Lu, H. S.
10.1101/2024.05.11.592234 — pathology — Posted on 2024-09-27
590 Reduced non-specific binding of super-resolution DNA-PAINT markers by Shielded DNA-PAINT labeling protocols
Lucinskaite, E.; Bokhobza, A. F. E.; Stannard, A.; Meletiou, A.; Estell, C.; West, S.; Di Michele, L.; Soeller, C.; Clowsley, A. H.
10.1101/2024.06.03.597143 — biophysics — Posted on 2024-09-27
592 Expression-based selection identifies a microglia-tropic AAV capsid for direct and CSF routes of administration in mice
Maguire, C.; Santoscoy, M. C.; Espinoza, P.; Hanlon, K. S.; Yang, L.; Nieland, L.; Ng, C.; Badr, C. E.; Hickman, S.; El-Khoury, J.; de la Cruz, D.; Griciuc, A.; Bennett, R.; Shen, S.
10.1101/2024.09.25.614546 — bioengineering — Posted on 2024-09-27
593 A unique interplay of access and selection shapes peritoneal metastasis evolution in colorectal cancer
Wassenaar, E. C.; Gorelick, A. N.; Hung, W.-T.; Cheek, D. M.; Kucukkose, E.; Lee, I.-H.; Blohmer, M.; Degner, S.; Giunta, P.; Wiezer, R. M.; Raicu, M. G.; Ubink, I.; Klaasen, S. J.; Lansu, N.; Watson, E. V.; Corcoran, R. B.; Boland, G.; Getz, G.; Kops, G. J.; Juric, D.; Lennerz, J. K.; Boerma, D.; Kranenburg, O.; Naxerova, K.
10.1101/2024.09.25.614736 — genetics — Posted on 2024-09-27
595 The genomic consequences and persistence of sociality in spiders
Ma, J.; Bechsgaard, J.; Aagaard, A.; Villesen, P.; Bilde, T.; Schierup, M.
10.1101/2024.04.22.590577 — evolutionary biology — Posted on 2024-09-27
597 The multi-level effect of chlorpyrifos during clownfish metamorphosis
Reynaud, M.; Vianello, S.; Lee, S.-H.; Salis, P.; Wu, K.; Frederich, B.; Lecchini, D.; Besseau, L.; Roux, N.; Laudet, V.
10.1101/2024.08.02.606305 — developmental biology — Posted on 2024-09-27
599 Autophagy alterations in white and brown adipose tissues of mice exercised under different training protocols
Tamargo-Gomez, I.; Fernandez-Sanjurjo, M.; Codina-Martinez, H.; Tomas-Zapico, C.; Iglesias-Gutierrez, E.; Fernandez, A. F.; Fernandez-Garcia, B.
10.1101/2022.09.05.505110 — molecular biology — Posted on 2024-09-27
600 Fis family members synergistically control the virulence of Legionella pneumophila
Andrea, C.; Bresson, J.; Ginevra, C.; Vianney, A.; Bailo, N.; Chapalain, A.; Attaiech, L.; Picq, K.; Ranquet, C.; Nasser, W.; Doublet, P.; KAY, E.
10.1101/2024.09.25.615009 — microbiology — Posted on 2024-09-27
603 The relationship between brain activation and mitochondrial complex I protein levels during cognitive function in healthy humans: an BCPP-EF PET and functional MRI study of task switching
Shatalina, E.; Whitehurst, T.; Chika Onwordi, E.; Whittington, A.; Mansur, A.; Arumuham, A.; Reis Marques, T.; Gunn, R. N.; Natesan, S.; Nour, M. M.; Rabiner, E. A.; Wall, M. B.; Howes, O. D.
10.1101/2024.09.25.614887 — neuroscience — Posted on 2024-09-27
604 Spontaneous brain activity and synaptic density in schizophrenia: a combined UCB-J PET and fMRI study
Shatalina, E.; Chika Onwordi, E.; Whitehurst, T.; Whittington, A.; Mansur, A.; Arumuham, A.; Reis Marques, T.; Gunn, R. N.; Natesan, S.; Rabiner, E. A.; Wall, M. B.; Howes, O. D.
10.1101/2024.09.25.614893 — neuroscience — Posted on 2024-09-27
609 Airway applied IVT mRNA vaccine needs specific sequence design and high standard purification that removes devastating dsRNA contaminant
Zhang, J.; Li, C.; Liu, Y.; Liao, R.; He, D.; Xu, L.; Chen, T.; Xiao, Q.; Luo, M.; Chen, Y.; Li, Y.; Zhu, H.; Rosenecker, J.; Ding, X.; Pei, S.; Guan, S.
10.1101/2024.09.22.614306 — synthetic biology — Posted on 2024-09-27
611 Genetic and phenotypic characterization of global Lupinus albus genetic resources for the development of a CORE collection
Tanwar, U. K.; Tomaszewska, M.; Czepiel, K.; Neji, M.; Jamil, H.; Rocchetti, L.; Pieri, A.; Bitocchi, E.; Bellucci, E.; Pipan, B.; Meglic, V.; Kroc, M.; Papa, R.; Susek, K.
10.1101/2024.09.25.614894 — plant biology — Posted on 2024-09-27
614 The Immune Landscape of Tumor-Associated Macrophage Reprogramming
Duval, F.; Lourenco, J.; Hicham, M.; Boivin, G.; Guichard, A.; Wyser-Rmili, C.; Fournier, N.; De Palma, M.; Mansouri, N.
10.1101/2024.09.25.614962 — cancer biology — Posted on 2024-09-27
616 Exploring Breast Cancer-Related Biochemical Changes in Circulating Extracellular Vesicles Using Raman Spectroscopy
Bonizzi, A.; Signati, L.; Grimaldi, M.; Truffi, M.; Piccotti, F.; Gagliardi, S.; Dotti, G.; Mazzucchelli, S.; Albasini, S.; Cazzola, R.; Bhowmik, D.; Narayana, C.; Corsi, F.; Morasso, C.
10.1101/2024.09.25.614667 — biophysics — Posted on 2024-09-27
617 HuBMAPR: an R Client for the HuBMAP Data Portal
Hou, C.; Ghazanfar, S.; Marini, F.; Morgan, M.; Hicks, S. C.
10.1101/2024.09.26.615227 — bioinformatics — Posted on 2024-09-27
619 Innovative platelet-derived extracellular vesicle drug delivery system for the treatment of corneal neovascularization
Liu, G.-S.; Chen, H.-A.; Chang, C.-Y.; Chen, Y.-J.; Wu, Y.-Y.; Widhibrata, A.; Yang, Y.-H.; Hsieh, E.-H.; Delila, L.; Lin, I.-C.; Burnouf, T.; Tseng, C.-L.
10.1101/2024.09.25.614855 — bioengineering — Posted on 2024-09-27
620 Whole genome methylation sequencing in blood from persons with mild cognitive impairment and dementia due to Alzheimer's disease identifies cognitive status
Madrid, A.; Papale, L. A.; Bergmann, P. E.; Breen, C.; Clark, L. R.; Asthana, S.; Johnson, S. C.; Keles, S.; Hogan, K. J.; Alisch, R. S.
10.1101/2024.09.26.615196 — genomics — Posted on 2024-09-27
626 Predictable sequential structure augments auditory sensitivity at threshold
Marin, N.; Gerenton, G.; Jean, H.; Paraouty, N.; Wallaert, N.; Lazard, D. S.; Doelling, K. B.; Arnal, L. H.
10.1101/2023.10.03.560670 — animal behavior and cognition — Posted on 2024-09-27
627 Zebrafish models of human-duplicated SRGAP2 reveal novel functions in microglia and visual system development
Uribe-Salazar, J. M.; Kaya, G.; Weyenberg, K. B.; Radke, B.; Hino, K. K.; Soto, D. C.; Shiu, J.-L.; Zhang, W.; Ingamells, C.; Haghani, N. K.; Xu, E.; Rosas, J.; Simo, S.; Miesfeld, J.; Glaser, T.; Baraban, S. C.; Jao, L.-E. C.; Dennis, M. Y.
10.1101/2024.09.11.612570 — genomics — Posted on 2024-09-27
628 Nanopore-based analysis unravels the genetic landscape and phylogenetic placement of human-infecting Trichuris species in Cote d'Ivoire, Tanzania, Uganda, and Laos
Rahman, N.; Bär, M. A.; Dommann, J.; Hürlimann, E.; Coulibaly, J. T.; Ali, S.; Sayasone, S.; Beinamaryo, P.; Keiser, J.; Schneeberger, P. H. H.
10.1101/2024.07.31.605962 — genomics — Posted on 2024-09-27
630 B cell alpha(v) integrin regulates germinal center derived lung-resident IgA B cell responses following influenza virus infection
Montiel-Armendariz, A.; Roe, K.; Lagos-Orellana, J.; Martinez-Castro, L. V.; Lacy-Hulbert, A.; Acharya, M.
10.1101/2024.04.03.587969 — immunology — Posted on 2024-09-27
633 Syngap1 Promotes Cognitive Function through Regulation of Cortical Sensorimotor Dynamics
Vaissiere, T.; Michaelson, S.; Creson, T.; Goins, J.; Fürth, D.; Balazsfi, D.; Rojas, C.; Golovin, R.; Meletis, K.; Miller, C.; O'Connor, D. H.; Fontolan, L.; Rumbaugh, G.
10.1101/2023.09.27.559787 — neuroscience — Posted on 2024-09-27
634 A temperature-inducible protein module for control of mammalian cell fate
Benman, W.; Huang, Z. D.; Iyengar, P.; Wilde, D.; Mumford, T.; Bugaj, L.
10.1101/2024.02.19.581019 — synthetic biology — Posted on 2024-09-27
635 Renal Proximal Tubule Cell-specific Megalin Deletion Does Not Affect Atherosclerosis But Induces Tubulointerstitial Nephritis in Mice Fed Western Diet
Amioka, N.; Franklin, M. K.; Kukida, M.; Zhu, L.; Moorleghen, J. J.; Howatt, D. A.; Katsumata, Y.; Mullick, A. E.; Yanagita, M.; Martinez-Irizarry, M.; Sandoval, R. M.; Dunn, K. W.; Sawada, H.; Daugherty, A.; Lu, H. S.
10.1101/2024.05.11.592234 — pathology — Posted on 2024-09-27
636 A single-cell multi-omic and spatial atlas of B cell lymphomas reveals differentiation drives intratumor heterogeneity
Fitzgerald, D.; Roider, T.; Baertsch, M. A.; Kibler, A.; Horlova, A.; Chung, E. K.; Voehringer, H.; Mathioudaki, A.; Budeus, B.; Passerini, V.; Knoll, M.; Mammen, J.; Li, L.; Caille, L.; Czernilofsky, F.; Bruch, P. M.; Liebers, N.; Meyer-Bender, M.; Siebert, R.; Weigert, O.; Zaugg, J. B.; Nolan, G. P.; Seifert, M.; Dietrich, S.; Huber, W.
10.1101/2023.11.06.565756 — cancer biology — Posted on 2024-09-27
637 Lifestyle factors in the biomedical literature: An ontology and comprehensive resources for named entity recognition
Nourani, E.; Koutrouli, M.; Xie, Y.; Vagiaki, D.; Pyysalo, S.; Nastou, K.; Brunak, S.; Juhl Jensen, L.
10.1101/2024.06.13.598816 — bioinformatics — Posted on 2024-09-27
638 Engineering Human ARMMs as Therapeutic Non-Viral Vehicles for in vivo Delivery of Genome Editing Payloads
Wang, Q.; Liu, S.-L.; Zhao, W.-N.; von Kleeck, R.; Thomas, M.; Luther, K.; Vahramian, Z.; Sun, L.; Vyas, K.; Moharil, P.; Chatzinakos, C.; Semple, C. O.; Badji, J. A.; Gens, L.; Bryant, A.; Greenway, S.; Chang, C.-W.; Francoeur, A.; Valkov, N.; O'Brien, K.; Nabhan, J. F.
10.1101/2024.09.24.614725 — bioengineering — Posted on 2024-09-27
640 Enzymatic access to the rare ΔUA (1->4) Glc 3, 6, N-sulfated heparin disaccharide, implications for heparin quality control
Kandola, T. K.; Mycroft-West, C. J.; Andrade De Lima, M.; Turner, A.; Gardini, C.; Urso, E.; Miller, G.; Bisio, A.; Yates, E.; Guerrini, M.; Wu, L.; Skidmore, M.
10.1101/2024.09.26.615151 — biochemistry — Posted on 2024-09-27
641 Long-read sequencing and genome assembly of natural history collection samples and challenging specimens
Bein, B.; Chrysostomakis, I.; Arantes, L.; Brown, T.; Gerheim, C.; Schell, T.; Schneider, C.; Leushkin, E.; Chen, Z.; Sigwart, J.; Gonzalez, V.; Wong, L.; Santos, F.; Blom, M.; Mayer, F.; Mazzoni, C.; Boehne, A.; Winkler, S.; Greve, C.; Hiller, M.
10.1101/2024.03.04.583385 — genomics — Posted on 2024-09-27
642 Spatial Transcriptomics Sequencing of Mouse Liver at 2 Micron Resolution Using a Novel Spatial DNA Chip
Ding, X.; Hoff, K.; Swaminathan, R.; Koutrouli, M.; Pollom, S.; Huang, T.; Li, X.; Zhou, G.; Bai, Z.; Yu, S.; Xia, Z.; Jensen, L. J.; Crnogorac, F.; Yu, S.; McGall, G.; Edwards, J.; Zhou, W.
10.1101/2024.01.08.574734 — genomics — Posted on 2024-09-27
644 The synaptonemal complex aligns meiotic chromosomes by wetting
Gordon, S.; Rodriguez, A. A.; Gu, Y.; Corbett, K. D.; Lee, C. F.; Rog, O.
10.1101/2024.08.07.607092 — cell biology — Posted on 2024-09-27
645 Second impact of an acute total body irradiation on thymic epithelial cells
Namiki, K.; Muramatsu, W.; Miyao, T.; Ishii, H.; Endo, R.; Hagiwara, N.; Miyauchi, M.; Yoshida, M.; Akiyama, N.; Akiyama, T.
10.1101/2024.07.30.605780 — immunology — Posted on 2024-09-27
649 High-Sensitivity Analysis of Native Bacterial Biofilms Using Dynamic Nuclear Polarization-Enhanced Solid-State NMR
Byeon, C.-H.; Kinney, T.; Saricayir, H.; Hansen, K. H.; Scott, F.; Srinivasa, S.; Wells, M. K.; Mentink-Vigier, F.; Kim, W.; Akbey, U.
10.1101/2024.09.25.614951 — microbiology — Posted on 2024-09-27
652 Transcriptomics effects of per- and polyfluorinated alkyl substances in differentiated neuronal cells
Running, L.; Cristobal, J. R.; Karageorgiou, C.; Camdzic, M.; Aguilar, J. M.; Gokcumen, O.; Aga, D.; Atilla-Gokcumen, G. E.
10.1101/2024.01.26.577438 — pharmacology and toxicology — Posted on 2024-09-27
654 Combined physical and pharmaceutical anabolic osteoporosis therapies synergistically increase bone response and local mechanoregulation
Schulte, F. A.; Griesbach, J. K.; Weigt, C.; von Salis-Soglio, M.; Lambers, F. M.; Marques, F. C.; Kneissel, M.; Richards, P. J.; Kuhn, G. A.; Mueller, R.
10.1101/2024.05.16.594551 — bioengineering — Posted on 2024-09-27
655 Gene expansions contributing to human brain evolution
Soto, D. C.; Uribe-Salazar, J. M.; Kaya, G.; Valdarrago, R.; Sekar, A.; Haghani, N. K.; Hino, K.; La, G. N.; Mariano, N. A. F.; Ingamells, C.; Baraban, A. E.; Turner, T. N.; Green, E. D.; Simo, S.; Quon, G.; Andres, A.; Dennis, M. Y.
10.1101/2024.09.26.615256 — genomics — Posted on 2024-09-26
656 A side-by-side comparison of variant function measurements using deep mutational scanning and base editing
Sokirniy, I.; Inam, H.; Tomaszkiewicz, M.; Reynolds, J.; McCandlish, D.; Pritchard, J. R.
10.1101/2024.06.30.601444 — genomics — Posted on 2024-09-26
658 Evolutionary trends in the emergence of skeletal cell types.
Damatac, A.; Koska, S.; Ullrich, K. K.; Domazet-Loso, T.; Klimovich, A.; Kaucka, M.
10.1101/2024.09.26.615131 — evolutionary biology — Posted on 2024-09-26
662 Systemic deficits in lipid homeostasis promote aging-associated impairments in B cell progenitor development
Vicenzi, S.; Gao, F.; Cote, P.; Hartman, J. D.; Avsharian, L. C.; Vora, A. A.; Rowe, R. G.; Li, H.; Skowronska-Krawczyk, D.; Crews, L. A.
10.1101/2024.09.26.614999 — cell biology — Posted on 2024-09-26
663 In vitro-generated inflammatory fibroblasts secrete extracellular matrix with biochemical and biophysical properties similar to tissue-remodelling fibroblasts
de la Jara Ortiz, F.; Cimmino, C.; Grech, K.; Huynen, M.; Janssen, E.; Wagenaar, V.; van Zwam, M. C.; van den Dries, K.; Ventre, M.; Cambi, A.
10.1101/2024.09.26.614950 — cell biology — Posted on 2024-09-26
666 Phospholipase D3 regulates TFEB/TFE3 metabolism to maintain lysosomal homeostasis
Wang, Y.; Rieschick, P.; Fernandez, W. R.; Appelbaum, N.; Tapia, C. C.; Kozunda, A.; Schrag, M.
10.1101/2024.09.26.615214 — cell biology — Posted on 2024-09-26
668 LRRC8 complexes are adenosine nucleotide release channels regulating platelet activation and arterial thrombosis
Tranter, J. D.; Mikami, R. T.; Kumar, A.; Brown, G.; Abd El-Aziz, T. M.; Zhao, Y.; Abraham, N.; Meyer, C.; Ajanel, A.; Xie, L.; Ashworth, K.; Hong, J.; Zhang, H.; Kumari, T.; Balutowski, A.; Liu, A.; Bark, D.; Nair, V. K.; Lasky, N. M.; Feng, Y.; Stitziel, N. O.; Lerner, D. J.; Campbell, R. A.; Di Paola, J.; Cho, J.; Sah, R.
10.1101/2024.09.26.615233 — cell biology — Posted on 2024-09-26
669 Immortalization of human valve interstitial cells: an in vitro tool for studying fibro-calcific aortic valve degeneration
Moschetta, D.; Massaiu, I.; Bertolini, F.; Valerio, V.; Rusconi, V.; De Giorgi, D.; Myasoedova, V. A.; Poggio, P.
10.1101/2024.09.26.615125 — cell biology — Posted on 2024-09-26
672 Endosomal Microautophagy is Activated by Specific Cellular Stresses in Trout Hepatocytes
VELEZ, E. J.; VERON, V.; GOUIS, J.; REJI, S.; DIAS, K.; HERPIN, A.; BEAUMATIN, F.; SEILIEZ, I.
10.1101/2024.09.26.615173 — cell biology — Posted on 2024-09-26
673 Quantitative physiology and biomass composition of Cyberlindnera jadinii in ethanol-grown cultures
Vieira-Lara, M. A.; Warmerdam, M.; de Hulster, E. A. F.; van den Broek, M.; Daran, J.-M.; Pronk, J. T.
10.1101/2024.08.31.610600 — microbiology — Posted on 2024-09-27
674 Cerebellar control of targeted tongue movements
Bina, L.; Ciapponi, C.; Ju, S.-y.; Wang, X.; Bosman, L. W. J.; De Zeeuw, C. I.
10.1101/2024.09.26.615128 — neuroscience — Posted on 2024-09-26
675 Cross-species evidence for a developmental origin of adult hypersomnia with loss of synaptic adhesion molecules beat-Ia/CADM2
Mace, K.; Zimmerman, A. J.; Chesi, A.; Doldur-Balli, F.; Kim, H.; Almeraya Del Valle, E.; Pack, A. I.; Grant, S. F.; Kayser, M. S.
10.1101/2024.09.25.615048 — neuroscience — Posted on 2024-09-26
677 Comparative transcriptomic rhythms in the mouse and human prefrontal cortex
Burns, J. N.; Jenkins, A. K.; Xue, X.; Petersen, K. A.; Ketchesin, K. D.; Perez, M. S.; Vadnie, C. A.; Scott, M. R.; Seney, M. L.; Tseng, G.; McClung, C. A.
10.1101/2024.09.26.615154 — neuroscience — Posted on 2024-09-26
680 Assessing neurocognitive maturation in early adolescence based on baby and adult functional brain landscapes
Kardan, O.; Jones, N.; Wheelock, M. D.; Michael, C.; Angstadt, M.; Molloy, M. F.; Cope, L. M.; Martz, M. M.; McCurry, K. L.; Hardee, J. E.; Rosenberg, M. D.; Weigard, A.; Hyde, L. W.; Sripada, C.; Heitzeg, M. M.
10.1101/2024.09.26.615215 — neuroscience — Posted on 2024-09-26
681 Individual-specific strategies inform category learning
Collina, J.; Erdil, G.; Xia, M.; Sheth, J.; Kording, K. P.; Cohen, Y.; Geffen, M. N.
10.1101/2024.09.26.615062 — neuroscience — Posted on 2024-09-26
683 A suite of enhancer AAVs and transgenic mouse lines for genetic access to cortical cell types
Ben-Simon, Y.; Hooper, M.; Narayan, S.; Daigle, T. L.; Dwivedi, D.; Way, S. W.; Oster, A.; Stafford, D. A.; Mich, J. K.; Taormina, M. J.; Martinez, R. A.; Opitz-Araya, X.; Roth, J. R.; Allen, S.; Ayala, A.; Bakken, T. E.; Barcelli, T.; Barta, S.; Bendrick, J. L.; Bertagnolli, D.; Bowlus, J.; Boyer, G.; Brouner, K.; Casian, B.; Casper, T.; Chakka, A. B.; Chakrabarty, R.; Chance, R. K.; Chavan, S.; Clark, M.; Departee, M.; Donadio, N.; Dotson, N.; Egdorf, T.; Gabitto, M.; Garcia, J.; Gary, A.; Gasperini, M.; Gloe, J.; Goldy, J.; Gore, B. B.; Graybuck, L.; Greisman, N.; Haeseleer, F.; Halterman,
10.1101/2024.06.10.597244 — neuroscience — Posted on 2024-09-27
684 Unveiling allopolyploidization-driven genome duplications through progressive analysis of deep genome skimming data
Xie, S.; Lin, X.; Wang, J.; Ma, D.; Zhang, Y.; Xu, C.; Ma, H.; Li, P.; Chen, D.; Zhong, X.; Ge, B.; Hodel, R. G. J.; Zhao, L.; Liu, B.
10.1101/2024.09.24.614835 — systems biology — Posted on 2024-09-26
685 CRISPR activation of Tfeb, a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength
James, A.; Hendrixson, J.; Kadhim, I.; Marques-Carvalho, A.; Laster, J.; Crawford, J.; Thostenson, J. D.; Sato, A.; Almeida, M.; Onal, M.
10.1101/2024.09.26.615175 — physiology — Posted on 2024-09-26
688 Single molecule spectrum dynamics imaging with 3D target-locking tracking
Sha, H.; Wu, Y.; Zhang, Y.; Feng, X.; Li, H.; Wang, Z.; Zhang, X.; Hou, S.
10.1101/2024.09.25.614875 — biophysics — Posted on 2024-09-26
691 Capture, mutual inhibition and release mechanism for aPKC-Par6 and its multi-site polarity substrate Lgl
Earl, C. P.; Cobbaut, M.; Carvalho, A. B.; Ivanova, M. E.; Briggs, D. C.; Morais-de-Sa, E.; Parker, P. J.; McDonald, N. Q.
10.1101/2024.09.26.615224 — biochemistry — Posted on 2024-09-26
693 Longitudinal evidence for the emergence of multiple intelligences in assistance dog puppies
Salomons, H.; Ferrans, M.; Cusato, C.; Moore, K.; Woods, V.; Bray, E.; Kennedy, B.; Block, T.; Douglas, L.; Roberts, A.; Gruen, M.; Hare, B.
10.1101/2024.09.26.615218 — animal behavior and cognition — Posted on 2024-09-26
694 Sedentary life accelerates epigenetic ageing in King penguins
Cristofari, R.; Davis, L.; Bardon, G.; Nitta Fernandes, F. A.; Figueroa, M. E.; Franzenburg, S.; Gauthier-Clerc, M.; Grande, F.; Heidrich, R.; Hukkanen, M.; Le Maho, Y.; Ollikainen, M.; Paciello, E.; Rampal, P.; Stenseth, N. C.; Trucchi, E.; Zahn, S.; Le Bohec, C.; Meyer, B. S.
10.1101/2024.09.24.614416 — genomics — Posted on 2024-09-26
695 The formation and propagation of human Robertsonian chromosomes
Gomes de Lima, L.; Guarracino, A.; Koren, S.; Potapova, T. A.; McKinney, S. A.; Rhie, A.; Solar, S. J.; Seidel, C.; Fagen, B.; Walenz, B. P.; Bouffard, G. G.; Brooks, S. Y.; Peterson, M.; Hall, K. E.; Crawford, J.; Young, A. C.; Pickett, B. D.; Garrison, E.; Phillippy, A. M.; Gerton, J. L.
10.1101/2024.09.24.614821 — genomics — Posted on 2024-09-26
697 A multidisciplinary investigation into whether Andean caravans reached the southern lowlands of the Parana-Plata basin during pre-Columbian times
Loponte, D.; Acosta, A.; Giovanardi, T.; Corriale, M. J.; Higgings, O.; Carbonera, M.; Buc, N.; Scaggion, C.; Bortolini, E.; Marciani, G.; Benazzi, S.; Rombola, L.; Westbury, M. V.
10.1101/2024.09.24.614829 — genomics — Posted on 2024-09-26
698 The protein structurome of Orthornavirae and its dark matter
Mutz, P.; Camargo, A. P.; Sahakyan, H.; Neri, U.; Butkovic, A.; Wolf, Y. I.; Krupovic, M.; Dolja, V. V.; Koonin, E. V.
10.1101/2024.09.25.615016 — evolutionary biology — Posted on 2024-09-26
701 Cisplatin exposure dysregulates pancreatic islet function in male mice
Basu, L.; McKay, K. S.; Hoyeck, M. P.; Grieco-St-Pierre, L.; Rick, K. R.; Poleo-Giordani, E.; Fadzeyeva, E.; Mulvihill, E. E.; Mennigen, J. A.; Bruin, J. E.
10.1101/2024.09.25.614996 — molecular biology — Posted on 2024-09-26
702 TRiC/CCT Chaperonin Governs RNA Polymerase II Activity in the Nucleus to Support RNA Homeostasis
Gvozdenov, Z.; Peng, A. Y. T.; Biswas, A.; Barcutean, Z.; Gestaut, D.; Frydman, J.; Struhl, K.; Freeman, B. C.
10.1101/2024.09.26.615188 — molecular biology — Posted on 2024-09-26
703 The coronavirus nsp14 exoribonuclease interface with the cofactor nsp10 is essential for efficient virus replication and enzymatic activity.
Grimes, S. L.; Heaton, B. E.; Anderson, M. L.; Burke, K. N.; Stevens, L. J.; Lu, X.; Heaton, N. S.; Denison, M. R.; Anderson-Daniels, J.
10.1101/2024.09.26.615217 — microbiology — Posted on 2024-09-26
705 A binding site for the antibiotic GE81112 in the ribosomal mRNA channel
Schedlbauer, A.; Han, X.; van Bakel, W.; Kaminishi, T.; Ochoa-Lizarralde, B.; Iturrioz, I.; Capuni, R.; Parry, R.; Zegarra, R.; Gil-Carton, D.; Lopez-Alonso, J. P.; Barragan Sanz, K.; Brandi, L.; Gualerzi, C. O.; Fucini, P.; Connell, S. R.
10.1101/2024.09.26.614503 — microbiology — Posted on 2024-09-26
707 Occurrence of "under-the-radar" antibiotic resistance in anthropogenically affected produce
Davidovich, C.; Erokhina, K.; Gupta, C. L.; Djordjevic, S. P.; Wyrsch, E. R.; Blum, S. E.; Cytryn, E.
10.1101/2024.09.26.615221 — microbiology — Posted on 2024-09-26
709 Human NK cell responses to the SARS-CoV-2 Spike269-277 peptide YLQPRTFLL
Bilev, E.; Schiele, S.; Foglietta, B.; Ljunggren, H.-G.; Hammer, Q.
10.1101/2024.09.26.613632 — immunology — Posted on 2024-09-26
710 Leveraging Synthetic Virology for the Rapid Engineering of Vesicular Stomatitis Virus (VSV)
Moles, C. M.; Basu, R.; Weijmarshausen, P.; Ho, B.; Farhat, M.; Flaat, T.; Smith, B. F.
10.1101/2024.09.26.615165 — synthetic biology — Posted on 2024-09-26
711 Labels as a Feature: Network Homophily for Systematically Discovering human GPCR Drug-Target Interactions
Hansson, F. G.; Madsen, N. G.; Hansen, L. G.; Jakociunas, T.; Lengger, B.; Keasling, J. D.; Jensen, M. K.; Acevedo-Rocha, C. G.; Jensen, E. D.
10.1101/2024.03.29.586957 — bioinformatics — Posted on 2024-09-26
712 A biosensor-based phage display selection method for automated, high-throughput Nanobody discovery
De Keyser, P.; Kalichuk, V.; Zogg, T.; Wohlkonig, A.; Schenck, S.; Brunner, J.; Pardon, E.; Steyaert, J.
10.1101/2024.06.26.600780 — bioengineering — Posted on 2024-09-26
715 Identifying ancient antibiotic resistance genes in archaeological dental calculus
Standeven, F. J.; Dahlquist-Axe, G.; Speller, C.; Tedder, A.; Meehan, C. J.
10.1101/2024.09.23.614435 — microbiology — Posted on 2024-09-26
717 BlueRecording: A Pipeline for the efficient calculation of extracellular recordings in large-scale neural circuit models
Tharayil, J. J.; Blanco Alonso, J.; Farcito, S.; Lloyd, B.; Romani, A.; Boci, E.; Cassara, A.; Schuermann, F.; Neufeld, E.; Kuster, N.; Reimann, M. W.
10.1101/2024.05.14.591849 — neuroscience — Posted on 2024-09-26
718 Four-dimensional label-free live cell image segmentation for predicting live birth potential of mouse embryos
Kanazawa, T.; Yao, T.; Takeshita, S.; Hirai, T.; Suenaga, R.; Yamada, T. G.; Tokuoka, Y.; Yamagata, K.; Funahashi, A.
10.1101/2024.09.25.614861 — systems biology — Posted on 2024-09-26
725 Enzymatic access to the rare ΔUA (1->4) Glc 3, 6, N-sulfated heparin disaccharide, implications for heparin quality control
Kandola, T. K.; Mycroft-West, C. J.; Andrade De Lima, M.; Turner, A.; Gardini, C.; Urso, E.; Miller, G.; Bisio, A.; Yates, E.; Wu, L.; Skidmore, M.
10.1101/2024.09.26.615151 — biochemistry — Posted on 2024-09-26
727 Ironing out the role of Nrf2 in cardiac iron metabolism during myocardial infarction
Jayakumar, D.; S NARASIMHAN, K. K.; Rajkumar, A.; Panchalingam, G. P.; Chandrasekar, N.; Ravikumar, V. C.; Periandavan, K.
10.1101/2024.09.25.615071 — biochemistry — Posted on 2024-09-26
730 Caspase-Activated DNase Localizes to Cancer Causing Translocation Breakpoints During Cell Differentiation
Alsowaida, D.; Larsen, B. D.; Hachmer, S.; Azimi, M.; Arezza, E.; Brunette, S.; Tur, S.; Palii, C. G.; Albraidy, B.; Sorensen, C. S.; Brand, M.; Dilworth, F. J.; Megeney, L. A.
10.1101/2024.09.24.614809 — genomics — Posted on 2024-09-26
731 A Global Assessment of Plant-Mite Mutualism and its Ecological Drivers
Myers, A.; Martin, B. S.; Yonenaga, J.; Agrawal, A. S.; Weber, M.
10.1101/2024.09.24.614831 — ecology — Posted on 2024-09-26
732 Rfx3 controls outer hair cell differentiation, maintenance, and hair bundle formation by regulating the expression of Insm1, Ikzf2, and Triobp genes
Zhang, P.; Wang, Y.; Guo, X.; Ma, L.; Zeng, X.; Feng, Z.; Liu, J.; Yan, M.; Gao, Y.; Dong, J.; Li, J.; Ling, J.; Wu, H.; Jing, Q.; Feng, Y.; Li, J.
10.1101/2024.09.24.614849 — developmental biology — Posted on 2024-09-26
736 SEISMICgraph: a web-based tool for RNA structure data visualization
Fuchs Wightman, F.; Yang, G.; Martin des Taillades, Y. J.; L'Esperance-Kerckhoff, C.; Grote, S.; Allan, M. F.; Herschlag, D.; Rouskin, S.; Hagler, L. D.
10.1101/2024.09.26.615187 — molecular biology — Posted on 2024-09-26
741 Diverse defense systems synergistically drive the microbe-virus arms race in deep sea cold seeps
Han, Y.; Liao, J.; Li, C.; Xing, F.; Peng, J.; Liu, X.; Xie, W.; Wu, F.; Jian, H.; Cheng, R.; Dong, X.
10.1101/2024.09.26.614923 — microbiology — Posted on 2024-09-26
744 Intestinal Epithelial PTPN2 Limits Pathobiont Colonization by Immune-Directed Antimicrobial Responses
Chatterjee, P.; Spalinger, M. R.; Acevedo, C.; Gries, C. M.; Manz, S.; Canale, V.; Santos, A. N.; Shawki, A.; Sayoc-Becerra, A.; Lei, H.; Crawford, M. S.; Eckmann, L.; Borneman, J.; McCole, D.
10.1101/2024.09.24.614848 — immunology — Posted on 2024-09-26
745 FROG Analysis Ensures the Reproducibility of Genome Scale Metabolic Models
Raman, K.; Kratochvil, M.; Olivier, B. G.; Konig, M.; Sengupta, P.; Baskaran, D. K. K.; Nguyen, T. V. N.; Lobo, D.; Wilken, S. E.; Tiwari, K. K.; Raghu, A. K.; Palanikumar, I.; Raajaraam, L.; Ibrahim, M.; Balakrishnan, S.; Umale, S.; Bergmann, F.; Malpani, T.; Satagopam, V. P.; Schneider, R.; Beber, M. E.; Keating, S.; Anton, M.; Renz, A.; Lakshmanan, M.; Lee, D.-Y.; Koduru, L.; Mostolizadeh, R.; Dias, O.; Cunha, E.; Oliveira, A.; Lee, Y. Q.; Zengler, K.; Santibanez-Palominos, R.; Kumar, M.; Barberis, M.; Puniya, B. L.; Helikar, T.; Dinh, H. V.; Suthers, P. F.; Maranas, C. D.; Casini, I.; Logh
10.1101/2024.09.24.614797 — systems biology — Posted on 2024-09-26
746 Tumor microenvironment distinctions between esophageal cancer subtypes explain varied immunotherapy responses
Baek, S.; Cha, J.; Hong, M.-H.; Kim, G.; Koh, Y. W.; Kim, D.; Hemberg, M.; Park, S. Y.; Kim, H. R.; Lee, I.
10.1101/2024.09.24.614705 — cancer biology — Posted on 2024-09-26
749 Generalizable Morphological Profiling of Cells by Interpretable Unsupervised Learning
Murthy, R. S.; Stassen, S. V.; Siu, D. M. D.; Lo, M. C. K.; Yip, G. G. K.; Tsia, K. K.
10.1101/2024.09.24.614684 — bioinformatics — Posted on 2024-09-26
750 Optical Control of Microtubule Accumulation and Dispersion by Tau-Derived Peptide-Fused Photo-Responsive Protein
Watari, S.; Inaba, H.; Lv, Q. H.; Ichikawa, M.; Iwasaki, T.; Wang, B.; Tadakuma, H.; Kakugo, A.; Matsuura, K.
10.1101/2024.09.24.614838 — bioengineering — Posted on 2024-09-26
751 Transcription swells chromosomes in vitro
Greiss, F.; Daube, S. S.; Noireaux, V.; Bar-Ziv, R.
10.1101/2024.09.25.614905 — biophysics — Posted on 2024-09-26
753 Topological Excitations govern Ordering Kinetics in Endothelial Cell Layers
Ruider, I.; Thijssen, K.; Vannier, D. R.; Paloschi, V.; Sciortino, A.; Doostmohammadi, A.; Bausch, A.
10.1101/2024.09.26.615134 — biophysics — Posted on 2024-09-26
755 The Roboscope: Smart and Fast Microscopy for Generic Event-Driven Acquisition
Bonnet, J.; El Habouz, Y.; Martin, C.; Guillout, M.; Ruel, L.; Giroux, B.; Demeautis, C.; Mercat, B.; Bouchareb, O.; Pecreaux, J.; Tramier, M.
10.1101/2024.09.24.614735 — bioengineering — Posted on 2024-09-26
756 Myocardial disarray drives metabolic inefficiency in human cardiomyocytes
Jouve, C.; Ruiz-velasco, A.; Donnarumma, E.; Le Borgne, R.; Momken, I.; Pereira, C.; Seguret, M.; Vermersch, E.; Vimont, E.; Nemazanyy, I.; Verbavatz, j.-m.; Bertrand, L.; Wai, T.; MERICSKAY, M.; Hulot, J.-S.
10.1101/2024.09.26.615170 — cell biology — Posted on 2024-09-26
760 Integrative systems neuroimmunology reveals leukocyte-expressing PAX6 as a critical predictor of major depressive disorder
Dias, H. D.; Adri, A. S.; Nobile, A. L.; de Oliveira, M. G.; Chung, E. N.; Bahia, I. A. F.; Fonseca, D. L. M.; Schimke, L. F.; Filgueiras, I. S.; Barcelos, P. M.; Nery do Vale, F. Y.; Dalmolin, R. J. S.; Cabral-Miranda, G.; Nakaya, H. J.; Hamani, C.; Bortoloti, R.; Wheeler, M. A.; Rezende, R. M.; Cabral-Marques, O.
10.1101/2024.09.25.614771 — systems biology — Posted on 2024-09-26
763 FerroEnrich: An Interactive web tool for computing Ferroptosis index and gene enrichment.
Tirumalasetty, M. B.; Choubey, M.; Wahiduzzaman, M.; Barua, R.; Mohiuddin, M. S.; Miao, Q.
10.1101/2024.09.25.615075 — bioinformatics — Posted on 2024-09-26
766 Synthesis of Novel N-Substituted β-Amino Acid Derivatives Bearing 2-Hydroxyphenyl Moieties as Promising Antimicrobial Candidates Targeting Multidrug-Resistant Gram-Positive Pathogens
Kavaliauskas, P.; Grybaite, B.; Sapijanskaite-Banevic, B.; Petraitiene, R.; Grigaleviciute, R.; Garcia, A.; Naing, E.; Mickevicius, V.; Petraitis, V.
10.1101/2024.09.25.615057 — microbiology — Posted on 2024-09-26
767 Continual integration of single-cell multimodal data with MIRACLE
Zhou, J.; He, Z.; Wang, J.; Hu, S.; Kan, T.; Dong, G.; Shi, J.; Liu, R.; Ou-Yang, L.; Bo, X.; Ying, X.
10.1101/2024.09.24.613833 — bioinformatics — Posted on 2024-09-26
769 The Cul3 ubiquitin ligase engages Insomniac as an adaptor to impact sleep and synaptic homeostasis
Li, Q.; Lim, K. Y.; Altawell, R.; Verderose, F.; Dong, C.; Martinez, J.; Li, X.; Dickman, D.; Stavropoulos, N.
10.1101/689471 — neuroscience — Posted on 2024-09-26
774 Tau condensation on DNA and localization on centromeres: A potential link to cell division
Park, C.; Jung, J.; Hong, Y.; Lee-Eom, C.; Rah, S.-H.; Yang, K.; Shin, J.; Jeong, A.; Hong, S.; Lee, J.-B.; Hwang, D. S.; Shon, M. J.
10.1101/2024.09.24.614852 — biophysics — Posted on 2024-09-26
778 GPR30 in spinal cholecystokinin-positive neurons modulates neuropathic pain via mediating descending facilitation
Chen, Q.; Wu, H.; Xie, S.; Zhu, F.; Xu, F.; Xu, Q.; Sun, L.; Yang, Y.; Xie, L.; Xie, J.; Li, H.; Dai, A.; Zhang, W.; Wang, L.; Jiao, C.; Zhang, H.; Xu, Z.-Z.; Chen, X.
10.1101/2024.09.24.614834 — neuroscience — Posted on 2024-09-26
779 Effect of Acute Alcohol Consumption in a Novel Rodent Model of Decision Making
Giri, A.; Batson, S. A.; Macias, A. Y.; Heaton, C. N.; Reyes, N. F.; Salcido, A. A.; Davila, L. D.; Rakocevic, L. I.; Beck, D. W.; Ibanez Alcala, R. J.; Hossain, S. B.; Vara, P.; Drammis, S. M.; Negishi, K.; Rosales, A. E.; O'Dell, L. E.; Moschak, T. M.; Goosens, K. A.; Friedman, A.
10.1101/2024.09.24.614857 — neuroscience — Posted on 2024-09-26
780 Slit3 Fragments Orchestrate Neurovascular Expansion and Thermogenesis in Brown Adipose Tissue
Duarte Afonso Serdan, T.; Cervantes, H.; Frank, B.; Tian, Q.; Choi, C. H. J.; Hoffmann, A.; Cohen, P.; Bluher, M.; Schwartz, G. J.; Shamsi, F.
10.1101/2024.09.24.613949 — physiology — Posted on 2024-09-26
783 Charged Molecular Glue Discovery Enabled by Targeted Degron Display
Zhuang, Z.; Byun, W. S.; Chrustowicz, J.; Kozicka, Z.; Li, V. L.; Abeja, D. M.; Donovan, K. A.; Sepic, S.; You, I.; Slabicki, M.; Fischer, E. S.; Hinshaw, S. M.; Ebert, B. L.; Schulman, B. A.; Gray, N. S.
10.1101/2024.09.24.614843 — biochemistry — Posted on 2024-09-26
784 Live imaging human embryos reveals mitotic errors and lineage specification prior to implantation
Abdelaal, A. A.; Mccarthy, A.; Karsa, A.; Muresan, L.; Elder, K.; Papathanasiou, A.; Snell, P.; Christie, L.; Wilding, M.; Steventon, B.; Niakan, K.
10.1101/2024.09.26.614906 — developmental biology — Posted on 2024-09-26
785 Transcription elongation factor ELOF1 is required for efficient somatic hypermutation and class switch recombination
Wu, L.; Yadavalli, A. D.; Rodrigues, G.; Xu, D.; Pintado-Urbanc, A.; Simon, M.; Wu, W.; Nussenzweig, A.; Schatz, D.
10.1101/2024.09.24.614732 — immunology — Posted on 2024-09-26
786 Grey Pineapple Mealybug, Dysmicoccus neobrevipes Beardsley: A New Devastating Pest of Tuberose in India
Firake, D. M.; Joshi, S.; Kumar, P. N.; Saha, T. N.; Dantuluri, V. S. R.; Prasad, K. V.
10.1101/2024.09.24.614774 — zoology — Posted on 2024-09-26
787 Distinct effects of acute and chronic blood loss anemia on vascular function after acute myocardial infarction
Solga, I.; Sahin, A.; Yogathasan, V.; Hofer, L.; Celik, F.; Rai, A. E.; Hosen, M. R.; Wischmann, P.; Becher, S.; Polzin, A.; Gerdes, N.; Jung, C.; Kelm, M.; Chennupati, R.
10.1101/2024.09.24.614629 — physiology — Posted on 2024-09-26
789 THOC1 complexes with SIN3A to regulate R-loops and promote glioblastoma progression
Budhiraja, S.; Baisiwala, S.; Cho, S.; Chojak, R.; Kazi, H. A.; Stepniak, A.; Perrault, E. N.; Chen, L.; Park, C. H.; Dmello, C.; Lin, P.; Sonabend, A. M.; Ahmed, A. U.
10.1101/2024.09.24.614748 — cancer biology — Posted on 2024-09-26
790 Exercise-induced extracellular vesicles mediate apoptosis in human colon cancer cells in an exercise intensity-dependent manner
Özerklig, B.; Turkel, I.; Yilmaz, M.; Vaizoglu, R. D.; Akan, H. S.; Dikmen, Z. G.; Saleem, A.; Kosar, S. N.
10.1101/2024.09.24.614165 — cancer biology — Posted on 2024-09-26
791 The Proteostasis Network is a Therapeutic Target in Acute Myeloid Leukemia
Lam, K.; Kim, Y. J.; Ong, C. M.; Liu, A. Z.; Zhou, F. J.; Sunshine, M. J.; Chua, B. A.; Vicenzi, S.; Ford, P.; Zhou, J.-H.; Hong, Y.; Bennett, E. J.; Crews, L. A.; Ball, E. D.; Signer, R. A. J.
10.1101/2024.09.24.614781 — cancer biology — Posted on 2024-09-26
794 Continual integration of single-cell multimodal data with MIRACLE
Zhou, J.; He, Z.; Wang, J.; Hu, S.; Kan, T.; Dong, G.; Shi, J.; Liu, R.; Ou-Yang, L.; Bo, X.; Ying, X.
10.1101/2024.09.24.613833 — bioinformatics — Posted on 2024-09-26
795 Protein Sequence Modelling with Bayesian Flow Networks
Atkinson, T.; Barrett, T. D.; Cameron, S.; Guloglu, B.; Greenig, M.; Robinson, L.; Graves, A.; Copoiu, L.; Laterre, A.
10.1101/2024.09.24.614734 — bioinformatics — Posted on 2024-09-26
796 Engineering Human ARMMs as Therapeutic Non-Viral Vehicles for in vivo Delivery of Genome Editing Payloads
Nabhan, J. F.; Wang, Q.; Liu, S.-L.; Zhao, W.-N.; von Kleeck, R.; Thomas, M.; Luther, K.; Vahramian, Z.; Sun, L.; Vyas, K.; Moharil, P.; Chatzinakos, C.; Semple, C. O.; Badji, J. A.; Gens, L.; Bryant, A.; Greenway, S.; Chang, C.-W.; Francoeur, A.; Valkov, N.; O'Brien, K.
10.1101/2024.09.24.614725 — bioengineering — Posted on 2024-09-26
797 Pooled nanoparticle screening using a chemical barcoding approach
Vaidya, K.; Regan, M. S.; Lin, J.; Houle, J.; Stopka, S. A.; Agar, N. Y. R.; Hammond, P. T.; Boehnke, N.
10.1101/2024.09.24.614746 — bioengineering — Posted on 2024-09-26
798 Location-biased β-arrestin conformations direct GPCR signaling
Pham, U.; Chundi, A.; Stepniewski, T. M.; Darbha, S.; Eiger, D. S.; Gazula, S.; Gardner, J.; Hicks, C.; Selent, J.; Rajagopal, S.
10.1101/2024.09.24.614742 — biochemistry — Posted on 2024-09-26
799 Distinct roles of the two BRCA2 DNA binding domains in DNA damage repair and replication fork preservation
Neal, F. E.; Sung, P. E.; Li, W.; Uhrig, M. E.; Sorensen, C. S.; Sharma, N.; Syed, S.; Burma, S.; Hromas, R.; Mazin, A.; Dray, E. S.; Libich, D. S.; Olsen, S.; Wasmuth, E. V.; Zhao, W.; Kwon, Y.; Wiese, C.
10.1101/2024.09.24.614752 — biochemistry — Posted on 2024-09-26
800 Expansion in situ genome sequencing links nuclear abnormalities to hotspots of aberrant euchromatin repression
Labade, A. S.; Chiang, Z. D.; Comenho, C.; Reginato, P. L.; Payne, A. C.; Earl, A. S.; Shrestha, R.; Duarte, F. M.; Habibi, E.; Zhang, R.; Church, G. M.; Boyden, E.; Chen, F.; Buenrostro, J. D.
10.1101/2024.09.24.614614 — genomics — Posted on 2024-09-26
803 Integrating spatial profiles and cancer genomics to identify immune-infiltrated mismatch repair proficient colorectal cancers
Wala, J.; de Bruijn, I.; Coy, S.; Gagne, A.; Chan, S.; Chen, Y.-A.; Hoffer, J.; Muhlich, J.; Schultz, N.; Santagata, S.; Sorger, P.
10.1101/2024.09.24.614701 — cancer biology — Posted on 2024-09-26
804 Recognition of phylogenetically diverse pathogens through enzymatically amplified recruitment of RNF213
Crespillo-Casado, A.; Pothukuchi, P.; Naydenova, K.; Yip, M. C. J.; Young, J. M.; Boulanger, J.; Dharamdasani, V.; Harper, C.; Hammoudi, P.-M.; Otten, E. G.; Boyle, K. B.; Gogoi, M.; Malik, H. S.; Randow, F.
10.1101/2024.09.24.614677 — molecular biology — Posted on 2024-09-26
806 Cgas deficiency promotes tumor growth by supporting B cell persistence and angiogenesis
Chantawichitwong, P.; Kumpunya, S.; Wongtangprasert, T.; Visitchanakun, P.; Pisitkun, T.; Pisitkun, P.
10.1101/2024.09.24.614699 — cancer biology — Posted on 2024-09-26
812 Growth and defence in a unicellular microalga: the coexistence of r and K strategies
Liu, L.; Tang, S.; Liu, Y.; Zhang, B.; Zhong, Y.; Liu, D.; Zhou, J.; Cai, Z.
10.1101/2024.09.24.614695 — ecology — Posted on 2024-09-26
813 Turning the tables: Loss of adaptive immunity reverses sex differences in tuberculosis
Hertz, D.; Eggers, L.; von Borstel, L.; Goldmann, T.; Lotter, H.; Schneider, B. E.
10.1101/2024.09.24.614709 — immunology — Posted on 2024-09-26
814 Naturally acquired IgG responses to Plasmodium falciparum do not target the conserved termini of the malaria vaccine candidate merozoite surface protein 2
Zerebinski, J.; Margerie, L.; Han, N. S.; Moll, M.; Ritvos, M.; Jahnmatz, P.; Ahlborg, N.; Ngasala, B.; Rooth, I.; Sjoberg, R.; Sundling, C.; Yman, V.; Farnert, A.; Plaza, D. F.
10.1101/2024.09.24.614082 — immunology — Posted on 2024-09-26
815 Assessing the role of AtGRP7 arginine 141, a target of dimethylation by PRMT5, in flowering time control
Steffen, A.; Dombert, K.; Iglesias, M. J.; Nolte, C.; de Leone, M. J.; Yanovsky, M. J.; Mateos, J. L.; Staiger, D.
10.1101/2024.09.24.614656 — plant biology — Posted on 2024-09-26
816 Gene coexpression network analysis of galactomannan biosynthesis and endosperm maturation in species of the genus Coffea
Dussert, S.; Stravinides, A. K.; Serret, J.; Vaissayre, V.; Combes, M.-C.; Morcillo, F.; Lefort, E.; Rialle, S.; Etienne, H.; Lashermes, P.; Joet, T.
10.1101/2024.09.24.614716 — plant biology — Posted on 2024-09-26
818 Systemic extracellular acidification is a hallmark of aging
dos Santos, E.; Xie, Y.; Cuan, E.; Foley, A.; Taylor, M. E.; Andrew, I.; Young, G.; Trevaskis, N. L.; Cocheme, H. M.
10.1101/2024.09.24.614672 — physiology — Posted on 2024-09-26
820 BRDKRM: An Explainable Framework for Disease Modifying Drug Identification
Chandra, A.; Dey, A.; Chakraborty, M.; Maulik, U. B.; Bandyopadhyay, S.
10.1101/2024.09.24.614653 — bioinformatics — Posted on 2024-09-26
821 Characterisation of Gas Vesicles as Cavitation Nuclei for Ultrasound Therapy using Passive Acoustic Mapping
Smith, C. A. B.; Bar-Zion, A.; Wu, Q.; Malounda, D.; Bau, L.; Stride, E.; Shapiro, M. G.; Coussios, C. C.
10.1101/2024.09.24.614126 — bioengineering — Posted on 2024-09-26
828 Ribosomal RNA synthesis by RNA polymerase I is regulated by premature termination of transcription.
Azouzi, C.; Schwank, K.; Queille, S.; Kwapisz, M.; Aguirrebengoa, M.; Henras, A.; Lebaron, S.; Tschochner, H.; Lesne, A.; Beckouet, F.; Gadal, O.; DEZ, c.
10.1101/2023.11.27.568781 — molecular biology — Posted on 2024-09-26
830 Probing the role of synaptic adhesion molecule RTN4RL2 in setting up cochlear connectivity
Karagulyan, N.; Überegger, M.; Qi, Y.; Babai, N.; Hofer, F.; Johnson Chacko, L.; Wang, F.; Luque, M.; Glueckert, R.; Schrott-Fischer, A.; Hua, Y.; Moser, T.; Bandtlow, C.
10.1101/2024.09.16.613011 — neuroscience — Posted on 2024-09-26
831 Multimodal single-cell profiling reveals neuronal vulnerability and pathological cell states in focal cortical dysplasia
Galvao, I. C.; Lemoine, M.; Messias, L. A.; Araujo, P. A. O. R. A.; Geraldis, J. C.; Yasuda, C. L.; Alvim, M. K. M.; Ghizoni, E.; Tedeschi, H.; Cendes, F.; Rogerio, F.; Lopes-Cendes, I.; Veiga, D. F. T.
10.1101/2024.05.29.596419 — neuroscience — Posted on 2024-09-26
833 Cross-sectional brain age assessments are limited in predicting future brain change
Korbmacher, M.; Vidal-Pineiro, D.; Wang, M.-Y.; van der Meer, D.; Wolfers, T.; Nakua, H.; Eikefjord, E.; Andreassen, O.; Westlye, L. T.; Maximov, I. I.
10.1101/2024.09.11.612523 — neuroscience — Posted on 2024-09-26
834 Endosomal sorting protein SNX4 limits synaptic vesicle docking and release
Poppinga, J.; Barret, N. J.; Cornelisse, L. N.; Verhage, M.; van Weering, J. R. T.
10.1101/2024.03.15.584406 — neuroscience — Posted on 2024-09-26
836 PlantConnectome: knowledge graph encompassing >70,000 plant articles
Lim, S. C.; Fo, K.; Sunil, R. S.; Itharajula, M.; Chuah, Y. S.; Foo, H.; Davey, E. E.; Fullwood, M.; Thibault, G.; Mutwil, M.
10.1101/2023.07.11.548541 — bioinformatics — Posted on 2024-09-26
837 Membrane composition and curvature in SNX9-mediated actin polymerization
Vaishnav, P.; Shimo Kondo, H.; Gadsby, J. R.; Dobramysl, U.; Mason, J.; Atherton, J.; Gallop, J. L.
10.1101/2024.09.24.614710 — cell biology — Posted on 2024-09-26
838 SNRK regulates TGFbeta levels in atria to control cardiac fibrosis
Thirugnanam, K.; Rizvi, F.; Jahangir, A.; Homar, P.; Shabnam, F.; Palecek, S. P.; Kumar, S. N.; Pan, A.; Bai, X.; Sekine, H.; Ramchandran, R.
10.1101/2024.09.24.612951 — cell biology — Posted on 2024-09-26
839 Endo-IP and Lyso-IP Toolkit for Endolysosomal Profiling of Human Induced Neurons
Hundley, F. V.; Gonzalez-Lozano, M.; Gottschalk, L. M.; Cook, A. N. K.; Zhang, J.; Paulo, J. A.; Harper, J. W.
10.1101/2024.09.24.614704 — cell biology — Posted on 2024-09-26
840 Inhibition of Ribosome Biogenesis in vivo Causes p53-Dependent Death and p53-Independent Dysfunction
Cho, C. J.; Nguyen, T.; Rougeau, A. K.; Huang, Y.-Z.; To, S.; Lin, X.; Gamage, S. T.; Meier, J. L.; Mills, J. C.
10.1101/2024.09.25.614959 — cell biology — Posted on 2024-09-26
842 Bergeyella cardium variant induces unique cytoplasmic vacuolization cell death
Mao, R.; Pan, H.; Yang, L.; Li, Z.; Yu, X.; Li, Y.; Chen, Y.; Yu, Y.; Wang, W.; Gao, C.; Peng, J.; Xu, T.; Zhang, Y.; Qi, X.
10.1101/2024.09.24.614850 — cell biology — Posted on 2024-09-26
843 Real time imaging reveals a role for macrophage protrusive motility in melanoma invasion
Ramakrishnan, G.; Miskolci, V.; Hunter, M.; Giese, M. A.; Muench, D.; Hou, Y.; Eliceiri, K. W.; Lasarev, M. R.; White, R. M.; Huttenlocher, A.
10.1101/2024.09.25.614908 — cell biology — Posted on 2024-09-26
845 Low-affinity ligands of the epidermal growth factor receptor are long-range signal transmitters during collective cell migration of epithelial cells
Deguchi, E.; Lin, S.; Hirayama, D.; Matsuda, K.; Tanave, A.; Sumiyama, K.; Tsukiji, S.; Otani, T.; Furuse, M.; Sorkin, A.; Matsuda, M.; Terai, K.
10.1101/2024.09.25.614853 — cell biology — Posted on 2024-09-26
846 Senataxin and DNA-PKcs Redundantly Promote Non-Homologous End Joining Repair of DNA Double Strand Breaks During V(D)J Recombination
Chen, B.-R.; Pham, T.; Reynolds, L. D.; Dang, N.; Zhang, Y.; Manalang, K.; Matos-Rodrigues, G.; Neidigk, J. R.; Nussenzweig, A.; Tyler, J. K.; Sleckman, B. P.
10.1101/2024.09.25.615014 — cell biology — Posted on 2024-09-26
847 CTCF binding landscape is established by the epigenetic status of the nucleosome, well-positioned relative to CTCF motif orientation
Tajmul, M.; Bhatt, D. N.; Ruje, L.; Price, E.; Ji, Y.; Loukinov, D.; Teif, V. B.; Lobanenkov, V. V.; Pugacheva, E. M.
10.1101/2024.09.25.614770 — cell biology — Posted on 2024-09-26
851 Multi-omics identification of extracellular components of the fetal monkey and human neocortex.
Vilicich, F.; Vettiatil, D.; Kattapong Graber, S.; Nawsheen, N.; Patel, N.; Quezada, A.; Gurney, E.; Smith, E. M.; Nelson, H.; Pesci, S.; Atrio, J.; Moreno, N.; Jones, A.; Murphy, M.; Benfield, N.; Hennelbold, J.; Solansky, N.; Lisgo, S.; Glass, I.; Birth Defects Research Laboratory, ; Sidoli, S.
10.1101/2024.09.25.615077 — neuroscience — Posted on 2024-09-26
852 Sanctioning of bacterial cheaters by the host plant in nitrogen-fixing symbiosis between Medicago truncatula and Sinorhizobium meliloti
Chen, M.; Raisin, A.; Judkins, N.; Allard, P.-M.; Defossez, E.; Stumpe, M.; Yruela, I.; Becana, M.; Reinhardt, D.
10.1101/2024.09.24.614788 — plant biology — Posted on 2024-09-26
853 A haplotype-resolved chromosome-level genome assembly of Urochloa decumbens cv. Basilisk resolves its allopolyploid ancestry and composition
Ryan, C.; Fraser, F.; Irish, N.; Barker, T.; Knitlhoffer, V.; Durrant, A.; Reynolds, G.; Kaithakottil, G.; Swarbreck, D.; De Vega, J. J.
10.1101/2024.09.25.614935 — plant biology — Posted on 2024-09-26
856 Non-immunogenic and reversible transgene expression using self-amplifying RNA
Lim, T. K. Y.; Ritoux, A.; Paine, L. W.; Ferguson, L.; Abdul, T.; Smith, E. S. J.
10.1101/2024.09.24.614636 — bioengineering — Posted on 2024-09-26
859 Genomic mosaicism reveals developmental organization of trunk neural crest-derived ganglia
Vong, K. I.; Alvarez, Y. D.; Noel, G.; Barton, S. T.; Chung, C.; Howarth, R.; Meave, N.; Zhang, Q.; Jiwani, F.; Barrows, C.; Patel, A.; Kingsmore, S. F.; White, M. D.; Yang, X.; Gleeson, J. G.
10.1101/2024.09.25.615004 — developmental biology — Posted on 2024-09-26
862 AUK3 is required for faithful nuclear segregation in the bloodstream form of Trypanosoma brucei
Black, J. A.; Poulton, B. C.; Gonzaga, B. S.; Iskantar, A.; Tosi, L. R. O.; McCulloch, R.
10.1101/2024.09.24.614706 — cell biology — Posted on 2024-09-26
864 A human mitochondrial isoform of TRPV1 regulates intracellular Ca2+ simultaneously with mitochondrial thermolysis
Beignon, F.; Ducreux, S.; Tuifua, L.; Le Dantec, Y.; Lemao, M.; Goudenege, D.; Chevrollier, A.; Khiati, S.; Tricoire-leignel, H.; Gueguen, N.; Mattei, C.; LENAERS, G.
10.1101/2024.09.25.614940 — cell biology — Posted on 2024-09-26
865 Transcription arrest induces formation of protective RNA granules in mitochondria
Hansen, K. G.; Baxter-Koenigs, A.; Weiss, C. A. M.; McShane, E.; Churchman, L. S.
10.1101/2024.09.25.614902 — cell biology — Posted on 2024-09-26
866 Interactions among Merlin, Arkadia, and SKOR2 mediate NF2-associated Schwann cell proliferation in human.
Tang, P.-C.; Um, S.; Mayfield, A. B.; Bracho, O. R.; Del Castillo, C.; Dinh, C. T.; Dykxhoorn, D. M.; Liu, X. Z.
10.1101/2024.09.24.614711 — cell biology — Posted on 2024-09-26
867 An atlas of RNA-dependent proteins in cell division reveals the riboregulation of mitotic protein-protein interactions
Rajagopal, V.; Seiler, J.; Nasa, I.; Cantarella, S.; Theiss, J.; Herget, F.; Kaifer, B.; Schneider, M.; Helm, D.; Koenig, J.; Zarnack, K.; Diederichs, S.; Kettenbach, A. N.; Caudron-Herger, M.
10.1101/2024.09.25.614981 — cell biology — Posted on 2024-09-26
868 The human ciliopathy protein RSG1 links the CPLANE complex to transition zone architecture
Vazquez, N.; Lee, C.; Valenzuela, I.; Cusco, I.; Codina, M.; Martinez-Gil, N.; Valverde, D.; Lopez-Solarat, C.; Bruel, A.-L.; Thauvin-Robinet, C.; Steichen, E.; Filges, I.; Joset, P.; De Geyter, J.; Mooney, N.; Gardner, T.; Vaidyanathan, K.; Marcotte, E.; Roberson, E.; Phan, T.; Derderian, C.; Toriyama, M.; Demeter, J.; Chavez, M.; Aziz-Zanjani, M.; Jackson, P.; Reiter, J.; Tizzano, E.; Wallingford, J. B.
10.1101/2024.09.25.614984 — cell biology — Posted on 2024-09-26
870 An in vivo and in vitro spatiotemporal atlas of human midbrain development
Barral, S.; Budinger, D.; Puigdevall Costa, P.; Hall, G. T.; Jerber, J.; Roth, C.; Xenakis, T.; Marrosu, E.; Di Domenico, A.; Kilpinen, H.; Castellano, S.; Kurian, M. A.
10.1101/2024.09.25.613908 — neuroscience — Posted on 2024-09-26
872 Oxytocin receptor controls distinct components of pair bonding and development in prairie voles
Sharma, R.; Berendzen, K. M.; Everitt, A.; Wang, B.; Williams, G.; Wang, S.; Quine, K.; Larios, R. D.; Long, K. L. P.; Hoglen, N.; Sulaman, B. A.; Heath, M. C.; Sherman, M.; Kinkel, M.; Cai, A.; Galo, D.; Caamal, L. C.; Goodwin, N. L.; Beery, A.; Bales, K. L.; Pollard, K. S.; Willsey, A. J.; Manoli, D. S.
10.1101/2024.09.25.613753 — neuroscience — Posted on 2024-09-26
874 Cryo-EM structures of human GPR155 elucidate its regulatory and transport mechanisms
Sharma, M.; JAIJYAN, D. K.; NANDA, S.; SAMSO, M.; HU, W.; Singh, S.; Singh, A. K.
10.1101/2024.09.24.614577 — biochemistry — Posted on 2024-09-25
876 Highly sensitive in vivo detection of dynamic changes in enkephalins following acute stress
Mikati, M. O.; Erdmann-Gilmore, P.; Connors, R.; Conway, S. M.; Malone, J.; Woods, J.; Sprung, R. W.; Townsend, R. R.; Al-Hasani, R.
10.1101/2023.02.15.528745 — neuroscience — Posted on 2024-09-25
877 Metastasis of colon cancer requires Dickkopf-2 to generate cancer cells with Paneth cell properties
Shin, J. H.; Park, J.; Lim, J.; Jeong, J.; Dinesh, R. K.; Maher, S. E.; Kim, J.; Park, S.; Hong, J. Y.; Wysolmerski, J.; Choi, J.; Bothwell, A. L. M.
10.1101/2024.04.12.589235 — cancer biology — Posted on 2024-09-25
882 Structure of the complete extracellular bacterial flagellum reveals mechanism for flagellin incorporation
Einenkel, R.; Qin, K.; Schmidt, J.; Al-Otaibi, N. S.; Mann, D.; Drobnic, T.; Cohen, E. J.; Gonzalez-Rodriguez, N.; Harrowell, J.; Shmakova, E.; Beeby, M.; Erhardt, M.; Bergeron, J. R.
10.1101/2024.09.25.614892 — microbiology — Posted on 2024-09-25
884 Avian interferon regulatory factor (IRF) family reunion: IRF3 and IRF9 found
Ungrova, L.; Geryk, J.; Kohn, M.; Kucerova, D.; Krchlikova, V.; Hron, T.; Pecenka, V.; Pajer, P.; Galikova, E.; Pecnova, L.; Kaspers, B.; Hejnar, J.; Nehyba, J.; Elleder, D.
10.1101/2024.09.24.613690 — immunology — Posted on 2024-09-25
885 Recurrent cortical networks encode natural sensory statistics via sequence filtering
Deveau, C.; Zhou, Z.; LaFosse, P. K.; Deng, Y.; Mirbagheri, S.; Steinmetz, N.; Histed, M. H.
10.1101/2024.02.24.581890 — neuroscience — Posted on 2024-09-25
887 Signal sequences target enzymes and structural proteins to bacterial microcompartments and are critical for microcompartment formation
Johnson, E. R.; Kennedy, N. W.; Mills, C. E.; Liang, S.; Chandrasekar, S.; Nichols, T. M.; Rybnicky, G. A.; Tullman-Ercek, D.
10.1101/2024.09.25.615066 — synthetic biology — Posted on 2024-09-25
888 Directed evolution of an orthogonal transcription engine for programmable gene expression in eukaryotes
Kar, S.; Gardner, E. C.; Javanmardi, K.; Boutz, D. R.; Schroff, R.; Horton, A. P.; Segall-Shapiro, T. H.; Ellington, A. D.; Gollihar, J.
10.1101/2024.09.25.614978 — synthetic biology — Posted on 2024-09-25
889 Degradation of PET plastic with engineered environmental bacteria
Banks, A. M.; Abdulmutalib, U.; Sonnendecker, C.; Kim, J.; Bosomworth, C.; Brown, S.; Wei, R.; Alvarez-Ortega, C.; Pomposiello, P.; Avignone-Rossa, C.; Larrouy-Maumus, G.; Zimmermann, W.; Jimenez, J. I.
10.1101/2024.09.24.614569 — synthetic biology — Posted on 2024-09-25
890 Neuropathological evidence of reduced amyloid beta and neurofibrillary tangles in multiple sclerosis cortex
Pansieri, J.; Pisa, M.; Yee, S.; Gutnikova, A.; Ridgeon, E.; Hickman, R.; Spencer, J. I.; Esiri, M. M.; DeLuca, G. C.
10.1101/2024.09.24.613639 — pathology — Posted on 2024-09-25
891 Breast cancer spheroids prefer activated macrophages as an accomplice: An in vitro study
Teli, A.; Iyer, R.; Shanbhag, K.; Gawarguru, R.; Gayan, S.; Shaikh, S.; Tamhankar, A.; Kamat, S. S.; Dey, T.
10.1101/2024.09.24.614655 — cancer biology — Posted on 2024-09-25
895 Enabling Epitope Analysis of Glycoproteins via HDX-MS Using Antigens with Uni-formed N-linked Glycans
Ota, T.; Takayama, M.; Ishihara, T.; Sato, M.; Ono, S.; Futamata, R.; Fujitani, M.; Rokushima, M.
10.1101/2024.09.24.613422 — biochemistry — Posted on 2024-09-25
898 DNA methylation and demethylation driven regulation of sepsis
Saini, A. K.; Kumar, J.; Tyagi, P.; Gautam, V.; Khanna, R.; kumar, V.
10.1101/2024.09.25.614895 — molecular biology — Posted on 2024-09-25
900 Revisiting oxygen toxicity: evolution and adaptation to superoxide in a SOD-deficient bacterial pathogen
Huete, S. G.; Leyva, A.; Kornobis, E.; Cokelaer, T.; Lechat, P.; Monot, M.; Duran, R.; Picardeau, M.; BENAROUDJ, N.
10.1101/2024.09.25.614947 — microbiology — Posted on 2024-09-25
903 Nasal microbionts differentially colonize and elicit cytokines in human nasal epithelial organoids
Boyd, A. I.; Kafer, L. A.; F. Escapa, I.; Kambal, A.; Tariq, H.; Hilsenbeck, S. G.; Nguyen-Phuc, H.; Rajan, A.; Lensmire, J. M.; Patras, K. A.; Piedra, P. A.; Blutt, S. E.; Lemon, K. P.
10.1101/2024.09.25.614934 — microbiology — Posted on 2024-09-25
904 Identification of a novel mycovirus belonging to the ''flexivirus''-related family with icosahedral virion
Wu, C.-F.; Okada, R.; Neri, U.; Chang, Y.-C.; Ogawara, T.; Kitaura, K.; Komatsu, K.; Moriyama, H.
10.1101/2024.09.25.614901 — microbiology — Posted on 2024-09-25
907 High-Sensitivity Analysis of Native Bacterial Biofilms Using Dynamic Nuclear Polarization-Enhanced Solid-State NMR
Byeon, C.-H.; Kinney, T.; Saricayir, H.; Hansen, K. H.; Scott, F.; Srinivasa, S.; Wells, M. K.; Mentink-Vigier, F.; Kim, W.; Akbey, U.
10.1101/2024.09.25.614951 — microbiology — Posted on 2024-09-25
909 Heterotrophic diazotrophy along a river to lake continuum: lifestyle and contribution to N2 fixation
Geisler, E.; Siebner, H.; Kolton, M.; Sisma-Ventura, G.; Rahav, E.; Arnon, S.; Bar-Zeev, E.
10.1101/2024.09.25.614945 — microbiology — Posted on 2024-09-25
912 Non-Optical, Label-free Electrical Capacitance Imaging of Microorganisms
Incandela, J. T.; Hu, K.; Joshi, P.; Rosenstein, J. K.; Larkin, J. W.
10.1101/2024.09.25.615041 — microbiology — Posted on 2024-09-25
913 Mechanisms of AAV2 neutralization by human alpha-defensins
Porter, J. M.; Oswald, M. S.; Busuttil, K.; Emmanuel, S. N.; Bennett, A.; McKenna, R.; Smith, J. G.
10.1101/2024.09.25.614754 — microbiology — Posted on 2024-09-25
915 Failure of colonization following gut microbiota transfer exacerbates DSS-induced colitis
Gustafson, K. L.; Rodriguez, T. R.; McAdams, Z. L.; Coghill, L. M.; Ericsson, A. C.; Franklin, C. L.
10.1101/2024.09.25.614792 — microbiology — Posted on 2024-09-25
916 Detection of intra-tumoral microbiota from transcriptomic sequencing of Asian breast cancer
Yeo, L.-F.; Lee, A. W. Y.; Tee, P. Y. E.; Chin, J. S. F.; Lim, B. K.; Lim, J.; Teo, S.-H.; Pan, J.-W.
10.1101/2024.09.25.614900 — microbiology — Posted on 2024-09-25
918 Estrogenic control of reward prediction errors and reinforcement learning
Golden, C. E. M.; Martin, A. C.; Kaur, D.; Mah, A.; Levy, D. H.; Yamaguchi, T.; Lasek, A.; Lin, D.; Aoki, C.; Constantinople, C. M.
10.1101/2023.12.09.570945 — neuroscience — Posted on 2024-09-25
922 The impact of sugar diet on humidity preference, survival, and host landing in mosquitoes
Chen, S.-C.; Holmes, C. J.; Ajayi, O. M.; Goodhart, G.; Eaton, D.; Catlett, N.; Cady, T.; Tran, H.; Lutz, L. E.; Wang, L.; Girard, E.; Savino, J.; Bidiwala, A.; Benoit, J. B.
10.1101/2024.09.23.613762 — physiology — Posted on 2024-09-25
923 nSMase2-mediated exosome secretion shapes the tumor microenvironment to immunologically support pancreatic cancer
Hendley, A. M.; Ashe, S.; Urano, A.; Ng, M.; Phu, T. A.; Peng, X. L.; Luan, C.; Finger, A.-M.; Jang, G. H.; Kerper, N. R.; Berrios, D. I.; Jin, D.; Lee, J.; Riahi, I. R.; Gbenedio, O. M.; Chung, C.; Roose, J.; Yeh, J. J.; Gallinger, S.; Biankin, A. V.; OKane, G. M.; Ntranos, V.; Chang, D.; Dawson, D. W.; Kim, G. E.; Weaver, V. M.; Raffai, R. L.; Hebrok, M.
10.1101/2024.09.23.614610 — cancer biology — Posted on 2024-09-25
927 An Atlas of Linkage Disequilibrium Across Species
Zhu, T.-N.; Huang, X.; Yang, M.-y.; Qi, G.-A.; Zhang, Q.-X.; Lin, F.; Zhang, W.; Zhang, Z.; Jin, X.; Zheng, H.-F.; Xu, H.; Yu, S.; Chen, G.-B.
10.1101/2024.09.24.614726 — genetics — Posted on 2024-09-25
929 The role of pigments in light color variation of the firefly Photinus pyralis
Popecki, M. S.; Rogers, R. L.; Archer-Hartmann, S. A.; Wares, J. P.; Stanger-Hall, K. F.
10.1101/2024.09.23.614534 — evolutionary biology — Posted on 2024-09-25
931 First record of Culex pipiens (Diptera: Culicidae) in Alberta: Expanding distributions and ecotype patterns in a western Canadian province
Soghigian, J.; Pan, T.; Seal, M.; Shaw, H.; Mohanaraj, S.; Morinaga, G.; Coker, A.; Hogaboam, B.; Jenkins, M.
10.1101/2024.09.24.614553 — ecology — Posted on 2024-09-25
932 Universal Receptive System as a novel regulator of transcriptomic activity of Staphylococcus aureus
Tetz, G.; Kardava, K.; Vecherkovskaya, M.; Khodadadi-Jamayran, A.; Tsirigos, A.; Tetz, V.
10.1101/2024.09.11.612522 — microbiology — Posted on 2024-09-25
933 Auto-antibodies against interferons are common in people living with chronic hepatitis B virus infection and associate with PegIFN non-response
Fink, D. L.; Etoori, D.; Hill, R.; Idilli, O.; Kartikapallil, N.; Payne, O.; Griffith, S.; Bradford, H.; Mauri, C.; Kennedy, P. T. F.; McCoy, L. E.; Maini, M. K.; Gill, U. S.
10.1101/2024.09.24.614789 — immunology — Posted on 2024-09-25
934 Disruption of the Social Visual Pathway in Autism Spectrum Disorder
Li, C.; Park, H.; Awasthi, J.; Rolison, M.; Li, M.; Scheinost, D.; Chawarska, K.; Hampson, M.
10.1101/2024.09.24.614813 — neuroscience — Posted on 2024-09-25
936 Seizure propagation triggers a protective contralesional spreading depolarization during focal hippocampal stroke predominantly in freely behaving female mice
Boyce, A. K.; Fouad, Y.; Gom, R. C.; Ashby, D. M.; Martins-Silva, C.; Molina, L.; Fuzesi, T.; Ens, C.; Nicola, W.; McGirr, A.; Teskey, G. C.; Thompson, R. J.
10.1101/2023.08.31.555814 — neuroscience — Posted on 2024-09-25
937 High-Dimensional Mediation Analysis with Network Mediators: Applications to Pediatric Acute Lymphoblastic Leukemia.
Wang, J.; Lu, Z.-H.; Reddick, W. E.; Conklin, H. M.; Glass, J. O.; Jacola, L.; Onar-Thomas, A.; Jeha, S.; Cheng, C.; Zhou, X.; Li, Y.
10.1101/2024.09.23.614601 — cancer biology — Posted on 2024-09-25
940 Long-read whole-genome sequencing-based concurrent haplotyping and aneuploidy profiling of single cells
Zhao, Y.; Tsuiko, O.; Jatsenko, T.; Peeters, G.; Souche, E.; Geysens, M.; Dimitriadou, E.; Vanhie, A.; Peeraer, K.; Debrock, S.; Van Esch, H.; Vermeesch, J. R.
10.1101/2024.09.24.614469 — genomics — Posted on 2024-09-25
941 Cadherin 16 promotes sensory gating via the endocrine corpuscles of Stannius
Schloss, S. S.; Marshall, Z. Q.; Santistevan, N. J.; Gjorcheska, S.; Stenzel, A.; Barske, L.; Nelson, J. C.
10.1101/2024.09.23.614609 — genetics — Posted on 2024-09-25
943 The mean and variance of infection load reveal unseen host evolution
Walsman, J. C.; Streipert, S. H.; Briggs, C. J.; Wilber, M. Q.
10.1101/2024.09.24.614578 — ecology — Posted on 2024-09-25
944 Hematological phenotypes in GATA2 deficiency syndrome arise from secondary injuries and maladaptation to proliferation
Fernandez-Orth, J.; Koyunlar, C.; Weiss, J. M.; Gioacchino, E.; de Looper, H.; Andrieux, G.; ter Borg, M.; Zink, J.; Gonzalez Menendez, I.; Hoogenboezem, R.; Yigit, B.; Gussinklo, K. J.; Mulet-Lazaro, R.; Wantzen, C.; Pfeiffer, S.; Molnar, C.; Bindels, E.; Bohler, S.; Sanders, M.; Quintanilla- Martinez, L.; Wlodarski, M.; Boerries, M.; Touw, I. P.; Niemeyer, C.; Erlacher, M.; de Pater, E.
10.1101/2024.09.24.614663 — cell biology — Posted on 2024-09-25
945 Mitochondrial oxidation of the carbohydrate fuel driven by pyruvate dehydrogenase robustly enhances stemness of older and geriatric Intestinal Stem Cells
Ahmed, S.; Awwad, A.; Eddy, N.; Weber, G.; Shahid, Z.; Sethi, Z.; Labampa, J.; Murphy, R.; Roth, E. W.; Gustafson, K.; Shah, H.; Sundaresan, S.
10.1101/2024.09.23.614374 — cell biology — Posted on 2024-09-25
946 SARS-CoV-2 ORF3a Protein Impairs Syncytiotrophoblast Maturation, Alters ZO-1 Localization, and Shifts Autophagic Pathways in Trophoblast Cells and 3D Organoids
Kumar, D.; Karvas, R. M.; Jones, B.; McColl, E.; Diveley, E.; Jash, S.; Sharma, S.; Kelly, J.; Theunissen, T.; Mysorekar, I. U.
10.1101/2024.09.25.614931 — microbiology — Posted on 2024-09-25
947 Inflammation cellular platform (INCEPLAT) for testing anti-inflammatory compounds for SARS-CoV-2
LOPEZ-AYLLON, B. D.; MENDOZA-GARCIA, L.; DE LUCAS-RIUS, A.; GARCIA-GARCIA, T.; FERNANDEZ-RODRIGUEZ, R.; ROMERO-GUILLEN, A.; Serrat, J.; Zuniga, S.; REDONDO, N.; Siles-Lucas, M.; GARRIDO, J. J.; MONTOYA, M.
10.1101/2024.09.25.614910 — immunology — Posted on 2024-09-25
950 SUMO2 Inhibition Reverses Aberrant Epigenetic Rewiring Driven by Synovial Sarcoma Fusion Oncoproteins and Impairs Sarcomagenesis
Iyer, R.; Deshpande, A.; Pedgaonkar, A.; Bala, P. A.; Kim, T.; Brien, G. L.; Finlay, D.; Vuori, K.; Soragni, A.; Murad, R.; Deshpande, A. J.
10.1101/2024.09.23.614593 — cancer biology — Posted on 2024-09-25
951 Assembly and dynamics of the outer membrane exopolysaccharide transporter PelBC of Pseudomonas aeruginosa
Benedens, M.; Hernandez, C. R.; Straathof, S. A. P.; Loschwitz, J.; Berninghausen, O.; Maglia, G.; Beckmann, R.; Kedrov, A.
10.1101/2024.09.23.614597 — biophysics — Posted on 2024-09-25
954 Stepwise Isolation of Diverse Metabolic Cell Populations Using Sorting by Interfacial Tension (SIFT)
Shulman, M.; Mathew, T.; Trivedi, A.; Gholizadeh, A.; Colcord, C.; Wiley, R.; Allen, K. S.; Thangam, L.; Voss, K.; Abbyad, P.
10.1101/2024.09.23.612740 — bioengineering — Posted on 2024-09-25
956 Calculating and interpreting FST in the genomics era
de Jong, M. J.; van Oosterhout, C.; Hoelzel, R.; Janke, A.
10.1101/2024.09.24.614506 — genomics — Posted on 2024-09-25
957 Genetic analysis of the X-linked Adrenoleukodystrophy ABCD1 gene in Drosophila uncovers a role in Peroxisomal dynamics
Manor, J.; Jangam, S.; Chung, H.; Bhagwat, P.; Andrews, J.; Chester, H.; Kondo, S.; Srivastav, S.; Botas, J.; Moser, A.; Huguenin, S.; Wangler, M. F.
10.1101/2024.09.23.614586 — genetics — Posted on 2024-09-25
959 The whole genome analysis of four Orf virus strains from Europe and South America.
Cacciabue, M.; Moleres, J.; Lozano Calderon, L.; Echeverria, I.; de Pablo, L.; Glaria, I.; Konig, G.; Peralta, A.; Reina, R.
10.1101/2024.09.25.613117 — microbiology — Posted on 2024-09-25
960 Placentas from SARS-CoV-2 infection during pregnancy exhibit foci of oxidative stress and DNA damage
Nobrega, G.; McColl, E.; Tavares, A.; Souza, R.; Cecatti, J.; Costa, M.; Mysorekar, I. U.
10.1101/2024.09.25.614948 — microbiology — Posted on 2024-09-25
961 RNA-DCGen: Dual Constrained RNA Sequence Generation with LLM-Attack
Shahgir, H. S.; Ratul, M. R. Z.; Tahmid, M. T.; Sayeed, K. S.; Rahman, A.
10.1101/2024.09.23.614570 — bioinformatics — Posted on 2024-09-25
962 A Corollary Discharge Circuit in Human Speech
Khalilian-Gourtani, A.; Wang, R.; Chen, X.; Yu, L.; Dugan, P.; Friedman, D.; Doyle, W.; Devinsky, O.; Wang, Y.; Flinker, A.
10.1101/2022.09.12.507590 — neuroscience — Posted on 2024-09-25
963 Orexin population activity precisely reflects net body movement across behavioral and metabolic states
Tesmer, A. L.; Viskaitis, P.; Donegan, D.; Bracey, E.; Grujic, N.; Patriarchi, T.; Peleg-Raibstein, D.; Burdakov, D.
10.1101/2024.08.13.607750 — neuroscience — Posted on 2024-09-25
964 Adaptive arousal regulation: Pharmacologically shifting the peak of the Yerkes-Dodson curve by catecholaminergic enhancement of arousal
Beerendonk, L.; Mejias, J. F.; Nuiten, S. A.; de Gee, J. W.; Zantvoord, J. B.; Fahrenfort, J. J.; van Gaal, S.
10.1101/2024.09.11.612196 — neuroscience — Posted on 2024-09-25
965 Severe Osteoarthritis in Aged PANX3 Knockout Mice: Implications for a Novel Primary Osteoarthritis Model
Wakefield, B.; Tang, J.; Balanta Melo, J.; Hutchinson, J. L.; Kanji, R.; Herold, G.; O'Donnell, B. L.; Brooks, C.; Kiser, P.; Grol, M.; Seguin, C. A.; Plotkin, L. I.; Beier, F.; Penuela, S.
10.1101/2023.07.04.547676 — physiology — Posted on 2024-09-25
966 Ablation of hematopoietic stem cell derived adipocytes reduces tumor burden in syngeneic mouse models of high-grade serous carcinoma
Woodruff, E. R.; Bailey, C. A.; To, F.; Manda, V.; Maltzahn, J. K.; Sullivan, T. M.; Boorgula, M. P.; Recouvreux, M. S.; Vianzon, R.; Conrad, B.; Gavin, K. M.; Jordan, K. R.; Klemm, D. J.; Orsulic, S.; Bitler, B. G.; Watson, Z. L.
10.1101/2024.09.19.613924 — cancer biology — Posted on 2024-09-25
967 Single Cell Expression Analysis of Ductal Carcinoma in Situ Identifies Alterations in Epithelial Integrity
Qin, X.; Strand, S. H.; Lee, M. R.; van Ijzendoorn, D. G. P.; Zhu, C.; Vennam, S.; Varma, S.; Hall, A.; King, L.; Simpson, L.; Luo, X.; Colditz, G. A.; Jiang, S.; Hwang, E. S.; Marks, J. R.; Owzar, K.; West, R. B.
10.1101/2023.10.10.561724 — cancer biology — Posted on 2024-09-25
970 Global niche partitioning of purine and pyrimidine cross-feeding among ocean microbes
Braakman, R.; Satinsky, B.; O'Keefe, T. J.; Longnecker, K.; Hogle, S. L.; Becker, J. W.; Li, R. C.; Dooley, K.; Arellano, A.; Kido Soule, M. C.; Kujawinski, E. B.; Chisholm, S. W.
10.1101/2024.02.09.579562 — ecology — Posted on 2024-09-25
971 Inositol Hexaphosphate (InsP6) Activates the HDAC1/3 Epigenetic Axis to Maintain Intestinal Barrier Function
Chatterjee, S.; Preval, L. V.; Sin, Z.; Tran, N.; Ritter, K.; Su, X. B.; Centlivre, J. P.; Ragsac, S. J.; Van, R.; Park, S.; Han, M.; Liu, Q.; Hedlund, B. P.; Saiardi, A.; Jessen, H.; Guha, P.
10.1101/2024.09.15.613154 — cell biology — Posted on 2024-09-25
972 Hierarchical behavior control by a single class of interneurons
Huo, J.; Xu, T.; Liu, Q.; Polat, M.; Kumar, S.; Zhang, X.; Leifer, A. M.; Wen, Q.
10.1101/2023.03.13.532397 — neuroscience — Posted on 2024-09-25
973 Cross-sectional brain age assessments are limited in predicting future brain change
Korbmacher, M.; Vidal-Pineiro, D.; Wang, M.-Y.; van der Meer, D.; Wolfers, T.; Nakua, H.; Eikefjord, E.; Andreassen, O.; Westlye, L. T.; Maximov, I. I.
10.1101/2024.09.11.612523 — neuroscience — Posted on 2024-09-25
974 Coordinated stimulation of axon regenerative and neurodegenerative transcriptional programs by ATF4 following optic nerve injury
Somasundaram, P.; Farley, M. M.; Rudy, M. A.; Sigal, K.; Asencor, A. I.; Stefanoff, D. G.; Shah, M.; Goli, P.; Heo, J.; Wang, S.; Tran, N. M.; Watkins, T. A.
10.1101/2023.03.29.534798 — neuroscience — Posted on 2024-09-25
975 Variability of 7K and 11K SomaScan plasma proteomics assays
Candia, J.; Fantoni, G.; Delgado-Peraza, F.; Shehadeh, N.; Tanaka, T.; Moaddel, R.; Walker, K. A.; Ferrucci, L.
10.1101/2024.08.06.606813 — systems biology — Posted on 2024-09-25
976 Super-enhancer profiling reveals ThPOK/ZBTB7B, a CD4+ cell lineage commitment factor, as a master regulator that restricts breast cancer cells to a luminal non-migratory phenotype
Arcuschin, C. D.; Kahrizi, K.; Sayaman, R. W.; DiBenedetto, C.; Shen, Y.; Salaberry, P. J.; Zakroui, O.; Schwarzer, C.; Scapozza, A.; Betancur, P.; Saba, J. D.; Coppe, J.-P.; Barcellos-Hoff, M. H.; Kappes, D.; van 't Veer, L.; Schor, I. E.; Munoz, D. P.
10.1101/2024.09.21.614267 — cancer biology — Posted on 2024-09-25
982 The Temporal Dynamics of Metacognitive Experiences Track Rational Adaptations in Task Performance
Vermeylen, L.; Braem, S.; Ivanchei, I. I.; Desender, K.; Gonzalez-Garcia, C.; Garcia-Roman, J. M.; Ruz, M.; Notebaert, W.
10.1101/2023.09.26.559523 — neuroscience — Posted on 2024-09-25
984 Generation of a PARPi-sensitive homozygous BRCA1-methylated OVCAR8 cell line using targeted CRISPR gene editing
Nesic, K.; Beard, S.; Xu, L.; Kondrashova, O.; Vandenberg, C. J.; Rubin, A. F.; Zhang, F.; Dobrovic, A.; Waddell, N.; Scott, C. L.; Shield-Artin, K.; Wakefield, M. J.
10.1101/2024.09.23.614644 — cancer biology — Posted on 2024-09-25
994 Targeting CCRL2 enhances therapeutic outcomes in a tuberculosis mouse model
Wang, T.; Quijada, D.; Ahmenda, T.; Castillo, J. R.; Naji, N. S.; Peske, J. D.; Karakousis, P. C.; Paul, S.; Karantanos, T.; Karanika, S.
10.1101/2024.09.23.614576 — immunology — Posted on 2024-09-25
998 IGF2BP3 Promotes Autophagy-Mediated TNBC Metastasis via M6A-Dependent, Cap-Independent c-Met Translation
Wang, Z.; Li, Y.; Cai, M.; Zhang, X.; Xu, R.; Yang, H.; Huang, Y.; Shi, L.; Wei, J.; Ding, Q.
10.1101/2024.09.23.614652 — cancer biology — Posted on 2024-09-25
999 Extracellular phase separation mediates storage and release of thyroglobulin in the thyroid follicular lumen
Knowles, T.; Yao, Y.; Erkamp, N. A.; Sneideris, T.; Yang, X.; Scrutton, R.; Schneider, M.; Fischer, C. M.; Schoenmakers, E.; Schoenmakers, N.
10.1101/2024.09.23.614536 — biophysics — Posted on 2024-09-25
1002 Clustering individuals using INMTD: a novel versatile multi-view embedding framework integrating omics and imaging data
Li, Z.; Windels, S. F. L.; Malod-Dognin, N.; Weinberg, S. M.; Marazita, M. L.; Walsh, S.; Shriver, M. D.; Fardo, D. W.; Claes, P.; Przulj, N.; Van Steen, K.
10.1101/2024.09.23.614478 — bioinformatics — Posted on 2024-09-25
1005 Climate Adaptation and Genetic Differentiation in the Mosquito Species Culex tarsalis
Liao, Y.; Noorai, R. E.; Streich, J.; Saski, C. A.; Cohnstaedt, L. W.; Cooper, E. A.; Islam, T.
10.1101/2024.09.23.613315 — genomics — Posted on 2024-09-25
1006 Genomic signatures of coral adaptation and recovery following a mass mortality event
Fifer, J. E.; Speare, K.; Leinbach, S.; Hendricks, S.; Davies, S. W.; Rose, N.; Burkepile, D.; Adam, T.; Hofmann, G.; Strader, M.
10.1101/2024.09.23.614560 — evolutionary biology — Posted on 2024-09-25
1011 GDF3 promotes adipose tissue macrophage-mediated inflammation via altered chromatin accessibility during aging
Jang, I. H.; Kruglov, V.; Cholensky, S. H.; Smith, D. M.; Carey, A.; Bai, S.; Nottoli, T.; Bernlohr, D. A.; Camell, C. D.
10.1101/2024.09.23.614375 — immunology — Posted on 2024-09-25
1012 Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2G2019S model of Parkinson's disease
Gaertner, Z.; Oram, C.; Schneeweis, A.; Schonfeld, E.; Bolduc, C.; Chen, C.; Dombeck, D. A.; Parisiadou, L.; Poulin, J. F.; Awatramani, R.
10.1101/2024.06.06.597807 — neuroscience — Posted on 2024-09-25
1013 Caveolin-1 regulates context-dependent signaling and survival in Ewing Sarcoma.
Segal, D.; Wang, X.; Mazloom-Farsibaf, H.; Rajendran, D.; Butler, E.; Chen, B.; Chang, B.-J.; Ahuja, K.; Perny, A.; Bhatt, K.; Reed, D. K.; Castrillon, D.; Lee, J.; Jeffery, E.; Wang, L.; Williams, N. S.; Rajaram, S.; Fiolka, R. P.; Skapek, S. X.; Hon, G. C.; Amatruda, J.; Danuser, G.
10.1101/2024.09.23.614468 — cancer biology — Posted on 2024-09-25
1016 Lipid Peroxidation and Type I Interferon Coupling Fuels Pathogenic Macrophage Activation Causing Tuberculosis Susceptibility
Yabaji, S. M.; Zhernovkov, V.; Araveti, P. B.; Lata, S.; Rukhlenko, O. S.; Abdullatif, S. A.; Vanvalkenburg, A.; Alekseev, Y.; Ma, Q.; Dayama, G.; Lau, N. C.; Johnson, W. E.; Bishai, W. R.; Crossland, N. A.; Campbell, J. D.; Kholodenko, B. N.; Gimelbrant, A. A.; Kobzik, L.; Kramnik, I.
10.1101/2024.03.05.583602 — immunology — Posted on 2024-09-25
1019 Independent evolution of ipecac alkaloid biosynthesis
Colinas, M.; Morweiser, C.; Dittberner, O.; Chioca, B.; Alam, R.; Leucke, H.; Nakamura, Y.; Serna Guerrero, D. A.; Heinicke, S.; Kunert, M.; Wurlitzer, J.; Ploss, K.; Hong, B.; Grabe, V.; Lopes, A. A.; O'Connor, S. E.
10.1101/2024.09.23.614470 — plant biology — Posted on 2024-09-25
1020 MedGraphNet: Leveraging Multi-Relational Graph Neural Networks and Text Knowledge for Biomedical Predictions
Macaulay, O.; Servilla, M.; Virupakshappa, K.; Arredondo, D.; Hu, Y.; Tafoya, L.; Zhang, Y.; Sahu, A.
10.1101/2024.09.24.614782 — bioinformatics — Posted on 2024-09-25
1022 Complex genomic ancestry in southern regions and drivers of continental-level genetic diversity in the wolves of Asia
Hennelly, L.; Parreira, B. R.; Noble, A.; Scharff-Olsen, C.; Kemahi Aytekin, M. C.; Sekercioglu, C.; Kosintsev, P.; Paule, L.; Hulva, P.; Stenoien, H. K.; Habib, B.; Fatima, H.; Sarwar, G.; El-Haddad, S. P.; Hailer, F.; Sun, X.; Martins, N. F.; Gilbert, M. T. P.; Sinding, M.-H. S.; Sacks, B. N.; Gopalakrishnan, S.
10.1101/2024.09.18.613796 — evolutionary biology — Posted on 2024-09-25
1025 Dynamics of microglia-glioblastoma crosstalk at the far infiltration zone
Nebeling, F. C.; Fuhrmann, F.; Mittag, M.; Musacchio, F.; Gockel, N. E.; Friker, L. L.; Leonardelli, S.; Filser, S.; Deli, A.; Stork, M.; Bano, D.; Pietsch, T.; Parrinello, S.; Hoelzel, M.; Herrlinger, U.; Salomoni, P.; Fuhrmann, M.
10.1101/2024.09.23.614016 — cancer biology — Posted on 2024-09-25
1027 HiExM: high-throughput expansion microscopy enables scalable super-resolution imaging
Day, J. H.; Della Santina, C. M.; Maretich, P.; Auld, A. L.; Schneider, K. K.; Shin, T.; Boyden, E. S.; Boyer, L. A.
10.1101/2023.02.07.527509 — bioengineering — Posted on 2024-09-25
1028 Complex genetic variation in nearly complete human genomes
Logsdon, G. A.; Ebert, P.; Audano, P. A.; Loftus, M.; Porubsky, D.; Ebler, J.; Yilmaz, F.; Hallast, P.; Prodanov, T.; Yoo, D.; Paisie, C. A.; Harvey, W. T.; Zhao, X.; Martino, G. V.; Henglin, M.; Munson, K. M.; Rabbani, K.; Chin, C.-S.; Gu, B.; Ashraf, H.; Austine-Orimoloye, O.; Balachandran, P.; Bonder, M. J.; Cheng, H.; Chong, Z.; Crabtree, J.; Gerstein, M.; Guethlein, L. A.; Hasenfeld, P.; Hickey, G.; Hoekzema, K.; Hunt, S. E.; Jensen, M.; Jiang, Y.; Koren, S.; Kwon, Y.; Li, C.; Li, H.; Li, J.; Norman, P. J.; Oshima, K. K.; Paten, B.; Phillippy, A. M.; Pollock, N. R.; Rausch, T.; Rautiainen
10.1101/2024.09.24.614721 — genomics — Posted on 2024-09-25
1030 Genome assembly and genomic architecture of a prominent cold-resistant rapeseed germplasm
Wu, Z.; Zheng, G.; Sun, Y.; Dong, X.; Wang, Y.; Li, H.; Niu, Y.; Huang, Z.; Hu, J.; Liu, Z.
10.1101/2023.11.12.566742 — genomics — Posted on 2024-09-25
1031 The genomic consequences and persistence of sociality in spiders
Ma, J.; Bechsgaard, J.; Aagaard, A.; Villesen, P.; Bilde, T.; Schierup, M.
10.1101/2024.04.22.590577 — evolutionary biology — Posted on 2024-09-25
1032 NR2F2 is required in the embryonic testis for Fetal Leydig Cell development
Perea-Gomez, A.; Bellido Carreras, N.; Dhellemmes, M.; Tang, F.; Le Gallo, C.; Chaboissier, M.-C.
10.1101/2024.07.17.602099 — developmental biology — Posted on 2024-09-25
1033 Brain and cancer associated binding domain mutations provide insight into CTCF's relationship with chromatin and its contribution to gene regulation
Do, C.; Jiang, G.; Cova, G.; Katsifis, C. C.; Narducci, D. N.; Sakellaropoulos, T.; Vidal, R.; Lhoumaud, P.; Tsirigos, A.; Fara Regis, F.; Kakabadze, N.; Nora, E. P.; Noyes, M.; Hansen, A. S.; Skok, J. A.
10.1101/2024.01.11.575070 — molecular biology — Posted on 2024-09-25
1034 The type VI secretion system of Sinorhizobium fredii USDA257 is required for a successful symbiosis with Glycine max cv Pekin
Reyes-Perez, P.; Jimenez-Guerrero, I.; Sanchez-Reina, A.; Civantos, C.; Moreno-de Castro, N.; Bernal, P.; Perez-Montano, F.
10.1101/2023.12.14.571490 — microbiology — Posted on 2024-09-25
1035 Adaptation to high pressure; insights from the genome of an evolved Escherichia coli strain with increased piezotolerance
Allemann, M. N.; Ma, S.; Sztain, T.; Bartholow, T. G. G.; Marshall, I. P. G.; McCammon, A.; Burkart, M.; Allen, E. E.; Bartlett, D. H.; Marietou, A.
10.1101/2024.09.24.613341 — microbiology — Posted on 2024-09-25
1036 Macrophages redeploy functional cancer cell surface proteins following phagocytosis
Volk, R. F.; Casebeer, S. W.; Condon, A. C.; Zirak, B.; Manon, N.; Irkliyenko, I.; Liao, H.; Tao, S.; Pollini, T.; Ramani, V.; Maker, A.; Fidler, T.; Goodarzi, H.; Zaro, B. W.
10.1101/2024.09.23.613776 — immunology — Posted on 2024-09-25
1039 Neanderthal-derived variants shape craniofacial enhancer activity at a human disease locus
Uttley, K.; Juellig, H. J.; De Angelis, C.; Auer, J. M.; Bengani, H.; Long, H. K.
10.1101/2024.09.24.614243 — genetics — Posted on 2024-09-25
1040 Genes involved in protein folding and chromatin organization buffer genetic variation
Frickel, J.; Tawfeeq, M. T.; Baker, E.; Baco, S.; Rombout, J.; Voordeckers, K.; Jarosz, D. F.; Vonesch, S.; Verstrepen, K. J.
10.1101/2024.09.24.614041 — evolutionary biology — Posted on 2024-09-25
1041 AQP1- A regulatory factor associated with brown adipose tissue silencing
Cheng, C.; Blay, C.; Tsai, P.-Y.; Li, M.; Edwards, K.; Qu, Y.; Liu, Y.; Buettner, N.; Walter, C.; Snyder, M.; Costa, I.; Devuyst, O.; Barrow, J. J.
10.1101/2024.09.23.614599 — molecular biology — Posted on 2024-09-25
1042 Analysis of genetic requirements and nutrient availability for Staphylococcus aureus growth in cystic fibrosis sputum
Shull, L. M.; Wolter, D. J.; Kunkle, D. E.; Legg, K. A.; Giedroc, D. P.; Skaar, E. P.; Hoffman, L. R.; Reniere, M. L.
10.1101/2024.09.24.614743 — microbiology — Posted on 2024-09-25
1045 Valence-dependent synaptic plasticity drives approach and avoidance behavior in social context
Espinosa, P.; Girard, B.; Lucchini, M.; Campanelli, F.; Tiriticco, V.; mohrhauer, L.; Bellone, C.
10.1101/2022.11.08.515650 — neuroscience — Posted on 2024-09-25
1047 WHIRLY1 regulates aliphatic glucosinolate biosynthesis in early seedling development of Arabidopsis
Nguyen, L. T.; Moutesidi, P.; Ziegler, J.; Glasneck, A.; Khosravi, S.; Abel, S.; Hensel, G.; Krupinska, K.; Humbeck, K.
10.1101/2024.04.12.589156 — plant biology — Posted on 2024-09-25
1048 Tasting stiffness? The mechanical signature of plant-based and animal meat
St. Pierre, S. R.; Darwin, E. C.; Adil, D.; Aviles, M. C.; Date, A. M.; Dunne, R.; Lall, Y.; Vallecillo, M. P.; Medina, V. A. P.; Linka, K.; Levenston, M. E.; Kuhl, E.
10.1101/2024.04.25.591207 — bioengineering — Posted on 2024-09-25
1049 Whole Genome Sequencing and Assembly of the House Sparrow, Passer domesticus
Kumar, V.; Sharma, G.; Sharma, S.; Prasad, S.; Vaishnani, T.; Vishnudasan, D.; Maheswaran, G.; Desai, S.; Tyagi, K.; Tyagi, I.; PB, K. K.; Chaubey, G.; Suravajhala, P.
10.1101/2023.11.04.565608 — evolutionary biology — Posted on 2024-09-25
1050 Aryl-hydrocarbon receptor in smooth muscle cells protect against dioxin induced adverse remodeling of atherosclerosis
Qin, G.; Zhao, Q.; Fujita, A.; Damiani, I.; Easwaran, M.; Basu, S.; Gu, W.; Li, D. Y.; Worssam, M.; Palmisano, B.; Monteiro, J. P.; Ramste, M.; Kundu, R.; Nguyen, T.; Park, C.; Weldy, C. S.; Cheng, P. C.; Kim, J. B.
10.1101/2024.09.24.614572 — molecular biology — Posted on 2024-09-25
1052 Respiratory shedding of infectious SARS-CoV-2 Omicron XBB.1.41.1 lineage with increased evolutionary rate among captive white-tailed deer
Ferreira, F. C.; Pervin, T.; Tang, W. C.; Hediger, J.; Thomas, L. F.; Cook, W.; Cherry, M. J.; Neuman, B.; Hamer, G. L.; Hamer, S. A.
10.1101/2024.09.24.613938 — microbiology — Posted on 2024-09-25
1053 Altered oral microbiota of drug-resistant organism carriers exhibit impaired gram-negative pathogen inhibition
Zelasko, S.; Swaney, M. H.; Suh, W. S.; Sandstrom, S.; Carlson, C.; Cagnazzo, J.; Golfinos, A.; Fossen, J.; Andes, D.; Kalan, L.; Safdar, N.; Currie, C.
10.1101/2024.09.24.614756 — microbiology — Posted on 2024-09-25
1058 Molecular changes in agroinfiltrated leaves of Nicotiana benthamiana expressing suppressor of silencing P19 and coronavirus-like particles
Hamel, L.-P.; Poirier-Gravel, F.; Pare, M.-E.; Tardif, R.; Comeau, M.-A.; Lavoie, P.-O.; Langlois, A.; Goulet, M.-C.; Michaud, D.; D'Aoust, M.-A.
10.1101/2024.09.23.614541 — plant biology — Posted on 2024-09-25
1059 Multi-omic analyses unveil contrasting composition and spatial distribution of specialized metabolites in seeds of Camelina sativa and other Brassicaceae
Barreda, L.; Brosse, C.; Boutet, S.; Klewko, N.; De Vos, D.; Francois, T.; Collet, B.; Grain, D.; Boulard, C.; Totozafy, J. C.; Bernay, B.; Perreau, F.; Lepiniec, L.; Rajjou, L.; Corso, M.
10.1101/2024.05.31.596893 — plant biology — Posted on 2024-09-25
1060 Modulation of Stemness and Differentiation Regulators by Valproic Acid in Medulloblastoma
Freire, N. H.; Herlinger, A. L.; Vanini, J.; Dalmolin, M.; Fernandes, M. A. C.; Nor, C.; Ramaswamy, V.; de Farias, C. B.; Brunetto, A. T.; Brunetto, A. L.; Gregianin, L. J.; Jaeger, M. d. C.; Taylor, M. D.; Roesler, R.
10.1101/2024.09.23.614476 — cancer biology — Posted on 2024-09-25
1061 Resolving the Structure of a Guanine Quadruplex in TMPRSS2 Messenger RNA by Circular Dichroism and Molecular Modeling
D'Anna, L.; Froux, A.; Rainot, A.; Spinello, A.; Perricone, U.; Barbault, F.; Grandemange, S.; Barone, G.; Terenzi, A.; Monari, A.
10.1101/2024.07.29.605618 — biophysics — Posted on 2024-09-25
1062 High-throughput bacterial aggregation analysis in droplets
Saar-Abroi, M.; Lindpere, K.; Olman, T.; Sulp, F. L.; Kiir, K.; Sanka, I.; Bartkova, S.; Scheler, O.
10.1101/2024.09.24.613170 — bioinformatics — Posted on 2024-09-25
1063 ArchMap: A web-based platform for reference-based analysis of single-cell datasets
Lotfollahi, M.; Bright, C.; Skorobogat, R.; Dehkordi, M.; George, X.; Richter, S.; Topalova, A.; Luecken, M. D.; Theis, F. J.; Shitov, V.
10.1101/2024.09.19.613883 — bioinformatics — Posted on 2024-09-25
1065 Structural and Functional Glycosylation of the Abdala COVID-19 Vaccine
Burnap, S. A.; Calvaresi, V.; Cabrera, G.; Pousa, S.; Limonta, M.; Ramos, Y.; Gonzalez, L. J.; Harvey, D. J.; Struwe, W. B.
10.1101/2024.09.24.614759 — biochemistry — Posted on 2024-09-25
1066 Modeling protein-small molecule conformational ensembles with ChemNet
Anishchenko, I.; Kipnis, Y.; Kalvet, I.; Zhou, G.; Krishna, R.; Pellock, S. J.; Lauko, A.; Lee, G. R.; An, L.; Dauparas, J.; DiMaio, F.; Baker, D.
10.1101/2024.09.25.614868 — biochemistry — Posted on 2024-09-25
1067 Post-GWAS Prioritization of Genome-Phenome Associations in Sorghum
Pal, D.; Schaper, K.; Thompson, A.; Guo, J.; Jaiswal, P.; Lisle, C.; Cooper, L.; LeBauer, D.; Thessen, A.; Ross, A.
10.1101/2023.12.05.570238 — genomics — Posted on 2024-09-25
1068 Maternal genetic affinities of Konkani population in the southwest coast of India
Sequeira, J. J.; Kumar, L.; van Driem, G.; Thangaraj, K.; Mustak, M. S.
10.1101/2024.09.23.614647 — genetics — Posted on 2024-09-25
1069 Body mass change over winter is consistently sex-specific across roe deer (Capreolus capreolus) populations
Hewison, A. J. M.; Bonnot, N.; Gaillard, J.-M.; Kjellander, P.; Lemaitre, J.-F.; Morellet, N.; Pellerin, M.
10.1101/2022.09.09.507329 — ecology — Posted on 2024-09-25
1070 Berberine is a novel mitochondrial calcium uniporter (MCU) inhibitor that disrupts MCU-EMRE assembly
Zhao, H.; Chen, S.; Cao, N.; Wu, W.; Liu, G.; Gao, J.; Chen, J.; Li, T.; Lu, D.; Zeng, L.; Zhu, H.; Zhang, W.; Xia, Q.; Li, T.; Zhou, T.; Zhang, X.-M.; Li, A.-L.; Pan, X.
10.1101/2024.08.18.607892 — cell biology — Posted on 2024-09-25
1071 Optimized expansion microscopy reveals species-specific spindle microtubule organization in Xenopus egg extracts
Guilloux, G.; Kitaoka, M.; Mocaer, K.; Heichette, C.; Duchesne, L.; Heald, R.; Pecot, T.; Gibeaux, R.
10.1101/2024.09.11.612005 — cell biology — Posted on 2024-09-25
1073 PPFlow: Target-aware Peptide Design with Torsional Flow Matching
Lin, H.; Zhang, O.; Zhao, H.; Jiang, D.; Wu, L.; Liu, Z.; Huang, Y.; Li, S. Z.
10.1101/2024.03.07.583831 — molecular biology — Posted on 2024-09-25
1080 Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans
Mota, C.; Kim, K.; Son, Y. J.; Thak, E. J.; Lee, S.-B.; Kim, J.-E.; Yoon, J.-K.; Kang, M.-H.; Hwang, H.; Bahn, Y.-S.; Alspaugh, A.; Kang, H. A.
10.1101/2024.09.24.610715 — microbiology — Posted on 2024-09-25
1082 Dynamics of Spike-Specific Neutralizing Antibodies Across Five-Year Emerging SARS-CoV-2 Variants of Concern Reveal Conserved Epitopes that Protect Against Severe COVID-19
Zayou, L.; Prakash, S.; Vahed, H.; Dhanushkodi, N. R.; Quadiri, A.; Belmouden, A.; Lemkhente, Z.; Chentoufi, A.; Gil, D.; Ulmer, J. B.; BENMOHAMED, L.
10.1101/2024.09.22.614369 — immunology — Posted on 2024-09-25
1083 Non-destructive X-ray tomography of brain tissue ultrastructure
Bosch, C.; Aidukas, T.; Holler, M.; Pacureanu, A.; Mueller, E.; Peddie, C. J.; Zhang, Y.; Cook, P.; Collinson, L.; Bunk, O.; Menzel, A.; Guizar-Sicairos, M.; Aeppli, G.; Diaz, A.; Wanner, A.; Schaefer, A.
10.1101/2023.11.16.567403 — neuroscience — Posted on 2024-09-25
1086 Expression of a constitutively active nitrate reductase increases SARS-CoV-2 Spike protein production in Nicotiana benthamiana leaves that otherwise show traits of senescence
Hamel, L.-P.; Pare, M.-E.; Poirier-Gravel, F.; Tardif, R.; Comeau, M.-A.; Lavoie, P.-O.; langlois, A.; Goulet, M.-C.; D'Aoust, M.-A.; Michaud, D.
10.1101/2024.09.23.614552 — plant biology — Posted on 2024-09-25
1087 IGF2BP3 promotes the progression of gastric cancer by activating cGMP-PKG signaling pathway via targeting FBXO32
Si, Y.; Tian, B.; Zhang, R.; Xuan, M.; Liu, K.; Jiao, J.; Han, S.; Li, H.; Hu, Y.; Zhao, H.; He, W.; Wang, J.; Liu, T.; Yu, W.
10.1101/2024.06.28.601102 — cancer biology — Posted on 2024-09-25
1089 Targeted anticancer pre-vinylsulfone covalent inhibitors of carbonic anhydrase IX
Vaskevicius, A.; Baronas, D.; Leitans, J.; Kvietkauskaite, A.; Ruksenaite, A.; Manakova, E.; Toleikis, Z.; Kaupinis, A.; Kazaks, A.; Gedgaudas, M.; Mickeviciute, A.; Juozapaitiene, V.; Schioth, H.; Jaudzems, K.; Valius, M.; Tars, K.; Grazulis, S.; Meyer-Almes, F.-J.; Matuliene, J.; Zubriene, A.; Dudutiene, V.; Matulis, D.
10.1101/2024.05.20.594908 — biophysics — Posted on 2024-09-25
1091 GeoAB: Towards Realistic Antibody Design and Reliable Affinity Maturation
LIN, H.; Wu, L.; Yufei, H.; Liu, Y.; Zhang, O.; Zhou, Y.; Sun, R.; Li, S. Z.
10.1101/2024.05.15.594274 — bioinformatics — Posted on 2024-09-25
1092 Phosphoproteomic Analysis Identifies REPS1 as an Insulin- and Exercise-Responsive Signal Transducer to Glucose Uptake in Skeletal Muscle
Kjaergaard, J.; Lindqvist, C. B.; Quesada, J. P.; Jessen, S.; Schlabs, F.; Ehrlich, A.; Yonamine, C. Y.; Garcia-Urena, M.; Schmalbruch, J.; Small, L.; Thomassen, M.; Lemminger, A. K.; Eibye, K.; Gonzalez-Franquesa, A.; Stidsen, J. v.; hoejlund, k.; Zierath, J. R.; Kilpelainen, T.; Bangsbo, J.; Treebak, J. T.; Hostrup, M.; Deshmukh, A. S.
10.1101/2023.11.10.566644 — biochemistry — Posted on 2024-09-25
1093 CHAMP1 complex directs heterochromatin assembly and promotes homology-directed DNA repair
Li, F.; Zhang, T.; Syed, A.; Elbakry, A.; Holmer, N.; Nguyen, H.; Mukkavalli, S.; Greenberg, R. A.; D'Andrea, A. D.
10.1101/2024.09.23.614480 — molecular biology — Posted on 2024-09-25
1094 Oxydifficidin, a potent Neisseria gonorrhoeae antibiotic due to DedA assisted uptake and ribosomal protein RplL sensitivity
Kan, J.; Morales, A.; Hernandez, Y.; Ternei, M. A.; Lemetre, C.; Maclntyre, L. W.; Biais, N.; Brady, S. F.
10.1101/2024.05.27.596031 — microbiology — Posted on 2024-09-25
1095 IMMUNE AND MOLECULAR CORRELATES OF RESPONSE TO IMMUNOTHERAPY REVEALED BY BRAIN-METASTATIC MELANOMA MODELS.
Daugherty-Lopes, A.; Perez-Guijarro, E.; Gopalan, V.; Rappaport, J.; Chen, Q.; Huang, A.; Lam, K. C.; Chin, S.; Ebersole, J.; Wu, E.; Needle, G. A.; Church, I.; Kyriakopoulos, G.; Xie, S.; Zaho, Y.; Gruen, C.; Sassano, A.; Araya, R. E.; Thorkelsson, A.; Smith, C.; Lee, M. P.; Hannenhalli, S.; Day, C.-P.; Merlino, G.; Goldszmid, R. S.
10.1101/2024.08.26.609785 — immunology — Posted on 2024-09-25
1097 Subject-Agnostic Transformer-Based Neural Speech Decoding from Surface and Depth Electrode Signals
Chen, J.; CHEN, X.; Wang, R.; Le, C.; Khalilian-Gourtani, A.; Jensen, E.; Dugan, P.; Doyle, W.; Devinsky, O.; Friedman, D.; Flinker, A.; Wang, Y.
10.1101/2024.03.11.584533 — neuroscience — Posted on 2024-09-25
1099 The gut microbiota is a determinant of sexual dimorphism in ALS-linked TDP43 mice
Beraldi, E. J.; Lee, S.; Jiang, Y.; Rea, I. M.; Phull, R.; Keenan, C. M.; Stephens, M.; Bardhi, M.; Bankole, O.; Pfeffer, G.; Biernaskie, J.; McCoy, K. D.; Elinav, E.; Sharkey, K. A.; Nguyen, M. D.
10.1101/2024.08.29.610355 — physiology — Posted on 2024-09-25
1100 Epigenetic upregulation of carotid body angiotensin signaling increases blood pressure
Zhu, F.; Wang, Z.; Davis, K.; McSwiggin, H.; Zyuzin, J.; Liu, J.; Yan, W.; Rehan, V.; Jendzjowsky, N.
10.1101/2024.05.10.593589 — physiology — Posted on 2024-09-25
1101 Ultrafast Power Doppler Ultrasound Enables Longitudinal Tracking of Vascular Changes that Correlate with Immune Response After Radiotherapy
Martello, S. E.; Xia, J.; Kusunose, J.; Hacker, B. C.; Mayeaux, M. A.; Lin, E. J.; Hawkes, A.; Singh, A.; Caskey, C. F.; Rafat, M.
10.1101/2023.08.04.552076 — cancer biology — Posted on 2024-09-25
1102 An integrated single-cell atlas of the limb skeleton from development through adulthood
Herpelinck, T.; Ory, L.; Verbraeken, T.; Nasello, G.; Barzegari, M.; Bolander, J.; Luyten, F. P.; Tylzanowski, P.; Geris, L.
10.1101/2022.03.14.484345 — bioinformatics — Posted on 2024-09-25
1104 Higher-order epistasis within Pol II trigger loop haplotypes
Duan, B.; Qiu, C.; Lockless, S. W.; Sze, S.-H.; Kaplan, C. D.
10.1101/2024.01.20.576280 — genetics — Posted on 2024-09-25
1105 Optimizing and benchmarking polygenic risk scores with GWAS summary statistics
Zhao, Z.; Gruenloh, T.; Yan, M.; Wu, Y.; Sun, Z.; Miao, J.; Wu, Y.; Song, J.; Lu, Q.
10.1101/2022.10.26.513833 — genetics — Posted on 2024-09-25
1106 Evolution of drought resistance strategies following the introduction of white clover (Trifolium repens L.)
Hendrickson, B. T.; Stamps, C.; Patterson, C. M.; Strickland, H.; Foster, M. J.; Albano, L. J.; Kim, A.; Kim, P.; Kooyers, N. J.
10.1101/2024.09.03.611023 — evolutionary biology — Posted on 2024-09-25
1108 Using the visual cliff and pole descent assays to detect binocular disruption in mice
De Jesus-Cortes, H.; Cramer, T.; Bowen, D. A.; Reilly-Andujar, F.; Lu, S.; Gaier, E. D.; Bear, M. F.
10.1101/2023.05.29.542767 — neuroscience — Posted on 2024-09-25
1109 Olfactory ensheathing cells from adult female rats are hybrid glia that promote neural repair
Phelps, P. E.; Ha, S. M.; Khankan, R. R.; Mekonnen, M. A.; Juarez, G.; Ingraham Dixie, K. L.; Chen, Y.-W.; Yang, X.
10.1101/2023.12.20.572462 — neuroscience — Posted on 2024-09-25
1110 Medicago truncatula CORYNE regulates inflorescence meristem branching, nutrient signaling, and arbuscular mycorrhizal symbiosis
Orosz, J.; Lin, E. X.; Lindsay, P. L.; Kappes, M.; Bashyal, S.; Everett, H.; Gautam, C. K.; Jackson, D.; Mueller, L. M.
10.1101/2024.09.20.614181 — plant biology — Posted on 2024-09-25
1111 Fmo5 plays a sex-specific role in goblet cell maturation and mucus barrier formation
Schaller, M. L.; Sykes, M. M.; Mecano, J.; Solanki, S.; Huang, W.; Rebernick, R. J.; Beydoun, S.; Wang, E.; Bugarin-Lapuz, A.; Shah, Y. M.; Leiser, S. F.
10.1101/2024.04.05.588360 — physiology — Posted on 2024-09-25
1114 Hyperexcitability precedes CA3 hippocampal neurodegeneration in a dox-regulatable TDP-43 mouse model of ALS-FTD.
Rodemer, W.; Ra, I.; Jia, E.; Gujral, J.; Zhang, B.; Hoxha, K.; Xing, B.; Mehta, S.; Farag, M.; Porta, S.; Jensen, F. E.; Talos, D. M.; Lee, V. M.- Y.
10.1101/2024.09.24.612703 — neuroscience — Posted on 2024-09-24
1118 A Drosophila holidic diet optimised for growthand development
Sorge, S.; Girard, V.; Lampe, L.; Tixier, V.; Weaver, A.; Higgins, T.; Gould, A. P.
10.1101/2024.09.24.614722 — developmental biology — Posted on 2024-09-24
1121 Developmental regulation of endothelial-to-hematopoietic transition from induced pluripotent stem cells
Wellington, R.; Cheng, X.; Campbell, C. A.; Trapnell, C.; Espin-Palazon, R.; Hadland, B.; Doulatov, S.
10.1101/2024.09.24.612755 — developmental biology — Posted on 2024-09-24
1124 Elevated synaptic PKA activity and abnormal striatal dopamine signaling in Akap11 mutant mice, a genetic model of schizophrenia and bipolar disorder
Song, B. J.; Ge, Y.; Nicolella, A.; Kwon, M. J.; Lodder, B.; Bonanno, K.; Valle-Tojeiro, A.; Adeleye, J.; Geng, C.; Natarajan, S.; Picard, I.; Shepard, N.; Aryal, S.; Farsi, Z.; Liu, X.-M.; Morshed, N.; Nadaf, N. M.; Mandell, K. P.; Pribiag, H.; Simmons, S. K.; Mani, D. R.; Stevens, B.; Macosko, E. Z.; Levin, J. Z.; Sabatini, B. L.; Keshishian, H.; Carr, S. A.; Dejanovic, B.; Granger, A. J.; Sheng, M.
10.1101/2024.09.24.614783 — neuroscience — Posted on 2024-09-24
1127 Molecular Mechanisms Underlying the Spectral Shift in Zebrafish Cone Opsins
Chi, L. A.; Pandey, S. K.; Kolodziejczyk, W.; Lund-Andersen, P.; Barnes, J. E.; Kapusta, K.; Patel, J. S.
10.1101/2024.09.24.614827 — biochemistry — Posted on 2024-09-24
1130 Stimulating the regenerative capacity of the human retina with proneural transcription factors in 3D cultures
Wohlschlegel, J.; Kierney, F.; Arakelian, K. L.; Luxardi, G.; Suvarnpradip, N.; Hoffer, D.; Rieke, F.; Moshiri, A.; Reh, T. A.
10.1101/2024.09.24.614778 — developmental biology — Posted on 2024-09-24
1131 Watch-breaker: establishment of a microwell array-based miniaturized thymic organoid model suitable for high throughput applications.
Major, V.; Palmer, S.; Rouse, P.; Henderson, T.; Hubscher, T.; Sweetman, J.; Morys, J.; Bacon, A.; Chengrui, A.; Guiyun, Q.; Wang, Y.; Corsinotti, A.; Cholewa-Waclaw, J.; Chapman, S. J.; Lutolf, M. P.; Anderson, G.; Blackburn, C. C.
10.1101/2024.09.23.614441 — immunology — Posted on 2024-09-24
1132 Modulation of Stemness and Differentiation Regulators by Valproic Acid in Medulloblastoma
Freire, N. H.; Herlinger, A. L.; Vanini, J.; Dalmolin, M.; Fernandes, M. A. C.; Nor, C.; Ramaswamy, V.; de Farias, C. B.; Brunetto, A. T.; Brunetto, A. L.; Gregianin, L. J.; Jaeger, M. d. C.; Taylor, M. D.; Roesler, R.
10.1101/2024.09.23.614476 — cancer biology — Posted on 2024-09-24
1133 Nucleosome placement and polymer mechanics explain genomic contacts on 100kbp scales
Corrette, J.; Li, J.; Shao, H.; Veerasubramanian, P. K.; Spakowitz, A.; Downing, T. L.; Allard, J.
10.1101/2024.09.24.614727 — biophysics — Posted on 2024-09-24
1142 Evaluation of Potentially Toxic Elements in Soil and Potential Ecological Risks Generated by Environmental Liabilities in Tacna, Peru
Caceda Quiroz, C. J.; Maraza Choque, G. J.; Fora Quispe, G. L.; Farfan Pajuelo, D. G.; Obando Velarde, E. D.; Chiampo, F.; Carpio Mamani, M.
10.1101/2024.09.21.614289 — ecology — Posted on 2024-09-24
1145 Flagellar switch inverted repeat impacts flagellar invertibility and varies Clostridioides difficile RT027/MLST1 virulence.
Nhu, N. T. Q.; Lin, H.; Pigli, Y.; Sia, J. K.; Kuhn, P.; Snitkin, E. S.; Young, V. B.; Kamboj, M.; Pamer, E. G.; Rice, P. A.; Shen, A.; Dong, Q.
10.1101/2023.06.22.546185 — microbiology — Posted on 2024-09-24
1146 Prophages are Infrequently Associated With Antibiotic Resistance in Pseudomonas aeruginosa Clinical Isolates
Chang, T. H.; Pourtois, J.; Haddock, N.; Furkuawa, D.; Kelly, K. E.; Amanatullah, D.; Burgener, E. B.; Milla, C.; Banaei, N.; Bollyky, P.
10.1101/2024.06.02.595912 — microbiology — Posted on 2024-09-24
1147 Transcriptome profiling of dopaminergic neurons derived from an ADHD induced pluripotent stem cell (iPSC) model
Namipashaki, A.; Arnatkeviciute, A.; Hellyer, S. D.; Nowell, C. J.; Walsh, K. S.; Polo, J. M.; Gregory, K. J.; Bellgrove, M. A.; Hawi, Z.
10.1101/2024.09.22.614376 — neuroscience — Posted on 2024-09-24
1148 Displacement of extracellular chloride by sulfated glycosaminoglycans of the brain extracellular matrix
Normoyle, K. P.; Lillis, K. P.; Egawa, K.; McNally, M. A.; Paulchakrabarti, M.; Coudhury, B. P.; Lau, L. A.; Shiu, T.; Staley, K. J.
10.1101/2022.12.28.522113 — neuroscience — Posted on 2024-09-24
1153 Ablation of hematopoietic stem cell derived adipocytes reduces tumor burden in syngeneic mouse models of high-grade serous carcinoma
Woodruff, E. R.; Bailey, C. A.; To, F.; Manda, V.; Maltzahn, J. K.; Sullivan, T. M.; Boorgula, M. P.; Recouvreux, M. S.; Vianzon, R.; Conrad, B.; Gavin, K. M.; Jordan, K. R.; Klemm, D. J.; Orsulic, S.; Bitler, B. G.; Watson, Z. L.
10.1101/2024.09.19.613924 — cancer biology — Posted on 2024-09-24
1154 Camera Paths, Modeling, and Image Processing Tools for ArtiaX
Ermel, U. H.; Roth, P.; Wehrheim, M. H.; Moser, D.; Frangakis, A. S.
10.1101/2024.09.23.614454 — bioinformatics — Posted on 2024-09-24
1156 Evaluating Physiological Indicators in Detecting Deception and Truthfulness using the Comparison Question Test (CQT)
Rashid, A. M. S.; Carmichael, B.; Su, C.; Shi, K.; Lim, K.; Kumar, P. S.; Wan, N. J.; Govil, E.; Yap, D.
10.1101/2024.09.01.609623 — bioengineering — Posted on 2024-09-24
1162 The Hsf1-sHsp cascade has pan-antiviral activity in mosquito cells
Qu, J.; Schinkel, M.; Chiggiato, L.; Rosendo Machado, S.; Overheul, G. J.; Miesen, P.; van Rij, R. P.
10.1101/2023.02.21.529413 — microbiology — Posted on 2024-09-24
1164 Simultaneous Profiling of the Blood and Gut T and B Cell Repertoires in Crohn's Disease and Symptomatic Controls Illustrates Tissue-specific Alterations in the Immune Repertoire of Crohn's Disease Patients
Mahdy, A. K. H.; Schöpfel, V.; Huppertz-Hauss, G.; Perminow, G.; Tran, F.; Bang, C.; Hov, J.; Bengtson, M.-B.; Ricanek, P.; Opheim, R.; Aabrekk, T. B.; Detlie, T. E.; Kristensen, V. A.; Poyet, M.; Hoivik, M. L.; Franke, A.; ElAbd, H.
10.1101/2024.09.22.614337 — immunology — Posted on 2024-09-24
1165 Rab10 inactivation promotes AMPAR insertion and spine enlargement during long-term potentiation
Wang, J.; Nishiyama, J.; Parra-Bueno, P.; Okaz, E.; Oz, G.; Liu, X.; Watabe, T.; Suponitsky-Kroyter, I.; McGraw, T. E.; Szatmari, E. M.; Yasuda, R.
10.1101/2022.05.17.492345 — neuroscience — Posted on 2024-09-24
1167 Natural variation in salt-induced changes in root:shoot ratio reveals SR3G as a negative regulator of root suberization and salt resilience in Arabidopsis
Ishka, M. R.; Sussman, H.; Hu, Y.; Alqahtani, M. D.; Craft, E.; Sicat, R.; Wang, M.; Yu, L.; Ait-Haddou, R.; Li, B.; Drakakaki, G.; Nelson, A.; Pineros, M.; Korte, A.; Jaremko, L.; Testerink, C.; Tester, M.; Julkowska, M. M.
10.1101/2024.04.09.588564 — plant biology — Posted on 2024-09-24
1168 Mutational order and epistasis determine the consequences of FBXW7 mutations during colorectal cancer evolution
Chan, D. K. H.; Mandal, A.; Zhou, Y.; Collins, S. D.; Owen, R.; Bundred, J.; Fuchs, H.; James, S.; Vendrell, I.; Flannery, S.; Fawkner-Corbett, D.; Househam, J.; Graham, T. A.; Fischer, R.; Simmons, A.; Lu, X.; Buczacki, S. J. A.
10.1101/2023.08.25.554836 — cancer biology — Posted on 2024-09-24
1169 Defining the heterogeneous molecular landscape of lung cancer cell responses to epigenetic inhibition
Lin, C.; Sniezek, C. M.; McGann, C. D.; Karki, R.; Giglio, R. M.; Garcia, B. A.; McFaline-Figueroa, J. L.; Schweppe, D. K.
10.1101/2024.05.23.592075 — cancer biology — Posted on 2024-09-24
1170 Bifidobacterium pseudocatenulatum capsular exopolysaccharide enhances systemic anti-tumour immunity in pre-clinical breast cancer
Price, C. A.; Nicklin, A.; Kujawska, M.; Koev, T. T.; Ilker, N.; Fowler, W. J.; McKee, A. M.; Mitchel, L.; Rowe, M.; Taylor, J. A. G. E.; Benwell, C. J.; Dreger, S. A.; Muller, J.; Hall, L. J.; Robinson, S. D.
10.1101/2024.09.23.614466 — cancer biology — Posted on 2024-09-24
1171 Mammalian promoters are characterised by low occupancy and high turnover of RNA polymerase II
Chatsirisupachai, K.; Moene, C. J. I.; Kleinendorst, R.; Kreibich, E.; Molina, N.; Krebs, A.
10.1101/2024.09.23.614464 — genomics — Posted on 2024-09-24
1173 A Protein Blueprint of the Diatom CO2-Fixing Organelle
Nam, O.; Musial, S.; Demulder, M.; McKenzie, C.; Dowle, A.; Dowson, M.; Barrett, J.; Blaza, J. N.; Engel, B. D.; Mackinder, L.
10.1101/2023.10.26.564148 — cell biology — Posted on 2024-09-24
1174 Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis
CHANG, J.; PICKARD, A.; Herrera, J. A.; O'Keefe, S.; Hartshorn, M.; GARVA, R.; Hoyle, A.; Dingle, L.; Zeltz, C.; Wong, J.; Reid, A.; Venkateswaran, R. V.; Lu, Y.; Caswell, P.; High, S.; Gullberg, D.; KADLER, K. E.
10.1101/2021.03.25.436925 — cell biology — Posted on 2024-09-24
1175 Spatial transcriptomics identifies novel Pseudomonas aeruginosa virulence factors
Zhou, H.; Negron, O.; Abbondante, S.; Marshall, M.; Jones, B.; Ong, E.; Chumbler, N.; Tunkey, C.; Dixon, G.; Lin, H.; Plante, O.; Pearlman, E.; Gadjeva, M.
10.1101/2024.06.20.599896 — microbiology — Posted on 2024-09-24
1176 Jaeger: an accurate and fast deep-learning tool to detect bacteriophage sequences
Wijesekara, Y.; Wu, L.-Y.; Beeloo, R.; Rozwalak, P.; Hauptfeld, E.; Doijad, S. P.; Dutilh, B. E.; Kaderali, L.
10.1101/2024.09.24.612722 — bioinformatics — Posted on 2024-09-24
1179 CPT1A Mediates Radiation Sensitivity in Colorectal Cancer
Chen, Z.; Yu, L.; Zheng, Z.; Wang, X.; Guo, Q.; Chen, Y.; Zhang, Y.; Zhang, Y.; Xiao, J.; Chen, K.; Fan, H.; Ding, Y.
10.1101/2024.03.26.586752 — cancer biology — Posted on 2024-09-24
1185 microRNA-138-5p suppresses excitatory synaptic strength at the cerebellar input layer
Delvendahl, I.; Daswani, R.; Winterer, J.; Germain, P.-L.; Uhr, N. M.; Schratt, G.; Mueller, M.
10.1101/2024.09.24.613637 — neuroscience — Posted on 2024-09-24
1186 Cardiac responses to auditory irregularities reveal hierarchical information processing during sleep
Koroma, M.; Boulakis, P. A.; Raimondo, F. A.; Gialama, V.; Blume, C.; Strauss, M.; Demertzi, A.
10.1101/2024.09.24.614090 — neuroscience — Posted on 2024-09-24
1188 Temporal integration in human auditory cortex is predominantly yoked to absolute time, not structure duration
Norman-Haignere, S. V.; Keshishian, M. K.; Devinsky, O.; Doyle, W.; McKhann, G. M.; Schevon, C. A.; Flinker, A.; Mesgarani, N.
10.1101/2024.09.23.614358 — neuroscience — Posted on 2024-09-24
1190 Is there a ubiquitous spectrolaminar motif of local field potential power across primate neocortex?
Mackey, C. A.; Duecker, K.; Neymotin, S. A.; Dura-Bernal, S.; Haegens, S.; Barczak, A.; O'Connell, M. N.; Jones, S.; Ding, M.; Ghuman, A. S.; Schroeder, C. E.
10.1101/2024.09.18.613490 — neuroscience — Posted on 2024-09-24
1191 Metabolic mapping of the human solute carrier superfamily
Wiedmer, T.; Teoh, S. T.; Christodoulaki, E.; Wolf, G.; Tian, C.; Sedlyarov, V.; Jarret, A.; Leippe, P.; Frommelt, F.; Ingles-Prieto, A.; Lindinger, S.; Barbosa, B. M. G.; Onstein, S.; Klimek, C.; Garcia Murias, J.; Serrano, I.; Reil, D.; Santacruz, D.; Piotrowski, M.; Noell, S.; Bueschl, C.; Li, H.; Chi, G.; Mereiter, S.; Oliveira, T.; Penninger, J. M.; Sauer, D. B.; Steppan, C. M.; Viollet, C.; Klavins, K.; Hannich, J. T.; Goldmann, U.; Superti-Furga, G.
10.1101/2024.09.23.614124 — systems biology — Posted on 2024-09-24
1195 AI-Augmented R-Group Exploration in Medicinal Chemistry
Zhao, H.; Kwapien, K.; Nittinger, E.; Tyrchan, C.; Nilsson, M.; Berglund, S.; Czechtizky, W.
10.1101/2024.09.23.614417 — bioinformatics — Posted on 2024-09-24
1200 Prediction and design of transcriptional repressor domains with large-scale mutational scans and deep learning
Valbuena, R.; Nigam, A.; Tycko, J.; Suzuki, P.; Spees, K.; Aradhana, A.; Arana, S.; Du, P.; Patel, R. A.; Bintu, L.; Kundaje, A.; Bassik, M. C.
10.1101/2024.09.21.614253 — genomics — Posted on 2024-09-24
1201 Rfam 15: RNA families database in 2025
Ontiveros-Palacios, N.; Cooke, E.; Nawrocki, E. P.; Triebel, S.; Marz, M.; Rivas, E.; Griffiths-Jones, S.; Petrov, A. I.; Bateman, A.; Sweeney, B.
10.1101/2024.09.23.614430 — genomics — Posted on 2024-09-24
1202 Global diversity of soil-transmitted helminths reveals population-biased genetic variation that impacts diagnostic targets
Papaiakovou, M.; Waeschenbach, A.; Ajibola, O.; Ajjampur, S. S.; Anderson, R. M.; Bailey, R.; Benjamin Chung, J.; Cambra Pelleja, M.; Caro, N. R.; Chaima, D.; Cimino, R. O.; Cools, P.; Cossa, A.; Dunn, J.; Galagan, S.; Gandasegui, J.; Grau Pujol, B.; Houlder, E.; Ibikounle, M.; Jenkins, T. P.; Kalua, K.; Kjetland, E. F.; Krolewiecki, A. J.; Levecke, B.; Luty, A. J.; MacDonald, A.; Mandomando, I.; Manuel, M.; Martinez Valladares, M.; Mejia, R.; Mekonnen, Z.; Messa, A.; Mpairwe, H.; Muchisse, O.; Munoz, J.; Mwinzi, P.; Novela, V.; Odiere, M. R.; Sacoor, C.; Walson, J. L.; Williams, S. A.; Witek
10.1101/2024.09.23.614419 — genomics — Posted on 2024-09-24
1204 Ancient biomolecules suggest learned foraging strategy in extinct cave bears
Meleg, I. N.; Alberti, F.; Drucker, D. G.; Naparus-Aljancic, M.; Feurdean, A.; Robu, M.; Vlaicu, M.; Naito, Y.; Boroneant, A.; Carciumaru, M.; Nitu, E. C.; Hofreiter, M.; Bocherens, H.; Barlow, A.
10.1101/2024.09.23.614392 — evolutionary biology — Posted on 2024-09-24
1207 Small mammals and their burrows shape the distribution of Coccidioides in soils: a long-term ecological experiment
Head, J. R.; Camponuri, S. K.; Weaver, A. K.; Montoya, L.; Lee, E.; Radosevich, M. T.; Jones, I.; Wagner, R.; Bhattachan, A.; Campbell, G.; Keeney, N.; Collender, P. A.; Heaney, A. K.; Couper, L.; Colvin, K. A.; Larios, L.; Bean, W. T.; Taylor, J.; Remais, J. V.
10.1101/2024.09.21.613892 — ecology — Posted on 2024-09-24
1210 Maternal immunity protects offspring from enteric viral infection without negatively affecting humoral immune memory
Muleta, K. G.; Isling Paerregaard, S.; Van Dijl, S.; Sadik Mustafa, A.; Segren, N.; Alyamani, M.; Lindberg, G.; Yuan, J.; Lahl, K.
10.1101/2024.09.20.614185 — immunology — Posted on 2024-09-24
1211 Efficacy and limitations of combined A2.CAR Treg and anti-CD154 therapy in a mouse model of haplo-mismatched heart transplantation
Durgam, S. S.; Rosado sanchez, I.; Yin, D.; Speck, M.; Mojibian, M.; Sayin, I.; Hynes, G.; Alegre, M.-L.; Levings, M. K.; Chong, A. S.
10.1101/2024.09.20.614149 — immunology — Posted on 2024-09-24
1214 Embodied processing in whisker somatosensory cortex during exploratory behaviour in freely moving mice
Gantar, L.; Burgess, M. A.; Mansour, N.; Rusco-Portabella, J.; Namesna, A.; Gill, D.; Harris, I.; Orlowska-Feuer, P.; Ebrahimi, A.; Storchi, R.; Petersen, R. S.
10.1101/2024.09.24.614719 — neuroscience — Posted on 2024-09-24
1216 The endocannabinoid 2-arachidonoylglycerol is released and transported on demand via extracellular microvesicles
Straub, V. M.; Barti, B.; Tandar, S. T.; Stevens, A. F.; van der Wel, T.; Zhu, N.; Ruegger, J.; van der Horst, C.; Heitman, L. H.; Li, Y.; Stella, N.; van Hasselt, J. G. C.; Katona, I.; van der Stelt, M.
10.1101/2024.09.23.614520 — neuroscience — Posted on 2024-09-24
1217 CX3CR1 modulates migration of resident microglia towards brain injury
Wagner, J.; Hoyer, C.; Antony, H.; Lundgren, K.; Soliymani, R.; Crux, S.; Justus, L.; Keppler, K.; Steffen, J.; Kurts, C.; Engel, D. R.; Herms, J.; Lalowski, M.; Fuhrmann, M.
10.1101/2024.09.23.614458 — neuroscience — Posted on 2024-09-24
1218 Why do we have so many excitatory neurons?
Wang, Q.; Cardona, A.; Zlatic, M.; Vogelstein, J.; Priebe, C.
10.1101/2024.09.24.614724 — neuroscience — Posted on 2024-09-24
1219 Amyloid-β-induced Alteration of Fast and Localized Calcium Elevations in Cultured Astrocytes
Nakata, K.; Sakamoto, J.; Otomo, K.; Sato, M.; Ishii, H.; Tsutsumi, M.; Enoki, R.; Nemoto, T.
10.1101/2024.09.23.614604 — neuroscience — Posted on 2024-09-24
1223 From Genes to Pathways: A Curated Gene Approach to Accurate Pathway Reconstruction in Teleost Fish Transcriptomics
Herrera, M.; Vianello, S. D.; Mitchell, L.; Chamot, Z.; Lorin-Nebel, C.; Roux, N.; Besseau, L.; Gibert, Y.; Laudet, V.
10.1101/2024.09.23.614382 — systems biology — Posted on 2024-09-24
1229 Dense but not alpha granules of platelets are required for insulin secretion from pancreatic beta cells
Kolczynska-Matysiak, K.; Karwen, T.; Loeffler, M.; Hawro, I.; Kassouf, T.; Stegner, D.; Sumara, G.
10.1101/2024.09.23.614422 — physiology — Posted on 2024-09-24
1230 Heterogeneous Kinetics of Nanobubble Ultrasound Contrast Agent and Angiogenic Signaling in Head and Neck Cancer
Van Court, B.; Ciccaglione, M.; Neupert, B.; Knitz, M. W.; Maroney, S. P.; Nguyen, D.; Abdelazeem, K. N. M.; Exner, A. A.; Saviola, A. J.; Benninger, R. K. P.; Karam, S. D.
10.1101/2024.09.22.614362 — cancer biology — Posted on 2024-09-24
1232 MAX inactivation deregulates the MYC network and induces neuroendocrine neoplasia in multiple tissues
Freie, B.; Ibrahim, A. H.; Carroll, P. A.; Bronson, R. T.; Augert, A.; MacPherson, D.; Eisenman, R. N.
10.1101/2024.09.21.614255 — cancer biology — Posted on 2024-09-24
1233 Super-enhancer profiling reveals ThPOK/ZBTB7B, a CD4+ cell lineage commitment factor, as a master regulator that restricts breast cancer cells to a luminal non-migratory phenotype
Arcuschin, C. D.; Kahrizi, K.; Sayaman, R. W.; DiBenedetto, C.; Shen, Y.; Salaberry, P. J.; Zakroui, O.; Schwarzer, C.; Scapozza, A.; Betancur, P.; Saba, J. D.; Coppe, J.-P.; Barcellos-Hoff, M. H.; Kappes, D.; van 't Veer, L.; Schor, I. E.; Munoz, D. P.
10.1101/2024.09.21.614267 — cancer biology — Posted on 2024-09-24
1239 Building a literature knowledge base towards transparent biomedical AI
Huang, Y.; Han, Z.; Luo, X.; Luo, X.; Gao, Y.; Zhao, M.; Tang, F.; Wang, Y.; Chen, J.; Li, C.; Lu, X.; Qiu, J.; Deng, F.; Jiao, T.; Xue, D.; Feng, F.; Vu, T. H. H.; Guan, L.; Cartailler, J.-P.; Stitzel, M.; Chen, S.; Brissova, M.; Parker, S.; Liu, J.
10.1101/2024.09.22.614323 — bioinformatics — Posted on 2024-09-24
1240 Accurate non-invasive quantification of astaxanthin content using hyperspectral images and machine learning
Calderini, M.; Paakkonen, S.; Yli-Tuomola, A.; Timilsina, H.; Pulkkinen, K.; Polonen, I.; Salmi, P.
10.1101/2024.09.23.614444 — bioinformatics — Posted on 2024-09-24
1243 Multi-material volumetric bioprinting and plug-and-play suspension bath biofabrication via bioresin molecular weight tuning and multiwavelength optics
Ribezzi, D.; Zegwaart, J.-P.; van Gansbeke, T.; Tejo-Otero, A.; Florczak, S.; Aerts, J.; Delrot, P.; Hierholzer, A.; Fussenegger, M.; Malda, J.; Olijve, J.; Levato, R.
10.1101/2024.09.21.614231 — bioengineering — Posted on 2024-09-24
1244 PhysiofUS : a tissue-motion based method for heart and breathing rate assessment in neurofunctional ultrasound imaging
ZUCKER, N.; Le Meur-Diebolt, S.; Pereira, F. C.; Baranger, J.; Hurvitz, I.; Demene, C.; Osmanski, B.; ialy-radio, n.; Biran, V.; Baud, O.; Pezet, S.; Deffieux, T.; Tanter, M.
10.1101/2024.09.22.614324 — bioengineering — Posted on 2024-09-24
1245 Achieving Single Cell Acoustic Localisation with Deactivation Super Resolution
Smith, C. A. B.; Duan, M.; Yan, J.; Taylor, L.; Shapiro, M. G.; Tang, M.-X.
10.1101/2024.09.20.614052 — bioengineering — Posted on 2024-09-24
1247 Flexible graphene-based neurotechnology for high-precision deep brain mapping and neuromodulation in Parkinsonian rats
Ria, N.; Eladly, A.; Masvidal Codina, E.; Illa, X.; Guimera, A.; Hills, K.; Garcia, R.; Flaherty, S.; Prokop, M.; Wykes, R.; Kostarelos, K.; Garrido, J. A.
10.1101/2024.09.23.614449 — bioengineering — Posted on 2024-09-24
1254 Naturally occurring variation in a cytochrome P450 modifies thiabendazole responses independent of beta-tubulin
Collins, J.; Dilks, C. M.; Hahnel, S. R.; Rodriguez, B.; Fox, B. W.; Redman, E.; Yu, J.; Cooke, B.; Sihuta, K.; Zamanian, M.; Roy, P. J.; Schroeder, F. C.; Gilleard, J. S.; Andersen, E. C.
10.1101/2024.09.23.614411 — genetics — Posted on 2024-09-24
1257 Ocean carbon export can be predicted from ocean color-based phytoplankton communities
Kramer, S. J.; Jones, E. L.; Estapa, M. L.; Paul, N. L.; Rynearson, T. A.; Santoro, A. E.; Sudek, S.; Durkin, C. A.
10.1101/2024.09.21.613760 — ecology — Posted on 2024-09-24
1261 Selective preservation of fucose-rich oligosaccharides in the North Atlantic Ocean
Bligh, M.; Buck-Wiese, H.; Sichert, A.; Bercovici, S. K.; Hellige, I.; Marchant, H.; Iversen, M.; Sauer, U.; Dittmar, T.; Arnosti, C.; Liebeke, M.; Hehemann, J.-H.
10.1101/2024.09.20.613644 — ecology — Posted on 2024-09-24
1262 Shigella flexneri evades LPS ubiquitylation through IpaH1.4-mediated degradation of RNF213
Naydenova, K.; Boyle, K. B.; Pathe, C.; Pothukuchi, P.; Crespillo-Casado, A.; Scharte, F.; Hammoudi, P.-M.; Otten, E. G.; Randow, F.
10.1101/2024.09.24.614686 — molecular biology — Posted on 2024-09-24
1264 Evolutionary fingerprint in rodent PD1 confers weakened activity and enhanced tumor immunity compared to human PD1
Masubuchi, T.; Chen, L.; Marcel, N.; Wen, G. A.; Caron, C.; Zhang, J.; Zhao, Y.; Morris, G. P.; Chen, X.; Hedrick, S. M.; Lu, L.-F.; Wu, C.; Zou, Z.; Bui, J. D.; Hui, E.
10.1101/2024.09.21.614250 — immunology — Posted on 2024-09-24
1266 Intranasal immunization with CPAF combined with cyclic-di-AMP induces a memory CD4 T cell response and reduces bacterial burden following intravaginal infection with Chlamydia muridarum
Poston, T. B.; Girardi, J.; Kim, M.; Zwarycz, P.; Polson, A. G.; Yount, K. S.; Hanlan, C.; Jaras Salas, I.; Lammert, S. M.; Arroyo, D.; Bruno, T.; Wu, M.; Rozzelle, J.; Fairman, J.; Esser-Kahn, A. P.; Darville, T.
10.1101/2024.09.20.614154 — immunology — Posted on 2024-09-24
1267 Evaluation of tick salivary and midgut extracellular vesicles as anti-tick vaccines in White-tailed deer (Odocoileus virginianus)
Gonzalez Gonzalez, J.; Harvey, C.; Ribeiro-Silva, C. d. S.; Galvan-Leal, B.; Persinger, K. A.; Olafson, P. U.; Johnson, T. L.; Oliva Chavez, A. S.
10.1101/2024.09.20.614210 — immunology — Posted on 2024-09-24
1268 Effects of age on resting-state cortical networks
Gohil, C.; Kohl, O.; Pitt, J.; van Es, M. W. J.; Quinn, A. J.; Vidaurre, D.; Turner, M. R.; Nobre, A. C.; Woolrich, M. W.
10.1101/2024.09.23.614004 — neuroscience — Posted on 2024-09-24
1269 High-speed 3D Imaging with 25-Camera Multifocus Microscope
Hirata-Miyasaki, E.; Bajor, A. A.; Petterson, G. M.; Senftleben, M. L.; Fouke, K. E.; Graham, T. G. W.; John, D. D.; Morgan, J. R.; Haspel, G.; Abrahamsson, S.
10.1101/2024.09.23.614351 — neuroscience — Posted on 2024-09-24
1271 A toolbox for ablating excitatory and inhibitory synapses
Bareghamyan, A.; Deng, C.; Daoudi, S.; Nawy, S.; Lu, X.; Zhang, W.; Campbell, R. E.; Kramer, R.; Chenoweth, D. M.; Arnold, D. B.
10.1101/2024.09.23.614589 — neuroscience — Posted on 2024-09-24
1273 A stolen future: aberrant hippocampal neurogenesis produces glial cells in epilepsy
Segasby, T.; Sanaei, R.; Aleksejenko, N.; Mamad, O.; Henshall, D. C.; Floudas, A.; Heller, J. P.
10.1101/2024.09.23.614355 — neuroscience — Posted on 2024-09-24
1274 Distinct classes of antidepressants commonly act to shape pallidal structure and function in mice
Abe, Y.; Sugiura, Y.; Maeda, R.; Taira, S.; Yoshida, K.; Ibi, D.; Hashimoto, K.; Yagishita, S.; Tanaka, K. F.
10.1101/2024.09.23.614626 — neuroscience — Posted on 2024-09-24
1276 BDNF augmentation reverses cranial radiation therapy-induced cognitive decline and neurodegenerative consequences
El-Khatib, S. M.; Vagadia, A. R.; Le, A. C. D.; Ng, D. Q.; Baulch, J. E.; Du, M.; Tan, Z.; Xu, X.; Chan, A.; Acharya, M. M.
10.1101/2024.09.23.614590 — neuroscience — Posted on 2024-09-24
1279 Pleiotrophin deletion prevents high-fat diet-induced cognitive impairment, glial responses, and alterations of the perineuronal nets in the hippocampus
Caneque-Rufo, H.; Fontan-Baselga, T.; Galan-Llario, M.; Zuccaro, A.; Sanchez-Alonso, M. G.; Gramage, E.; Ramos-Alvarez, M. d. P.; Herradon, G.
10.1101/2024.09.23.614574 — neuroscience — Posted on 2024-09-24
1281 Auditory decision-making deficits after permanent noise-induced hearing loss
Berns, M. P.; Nunez, G. M.; Zhang, X.; Chavan, A.; Zemlianova, K.; Mowery, T. M.; Yao, J. D.
10.1101/2024.09.23.614535 — neuroscience — Posted on 2024-09-24
1283 Identification of Intrinsic Features for Cortical Separability of Human and Mouse Neurons
Yun, Z.; Ye, W.; Ji, N.; Wang, Y.; Rong, J.; Li, T.; Wang, R.; Li, Y.; Zhang, H.; Xu, H.; Mo, N.; Song, B.; Chen, X.; Wang, Y.; Mai, Y.; Ding, M.; Ding, S.-L.; Liu, L.; Zhang, L.; Peng, H.
10.1101/2024.09.23.614630 — neuroscience — Posted on 2024-09-24
1284 Higher-order and distributed synergistic functional interactions encode information gain in goal-directed learning
Combrisson, E.; Basanisi, R.; Neri, M.; Auzias, G.; Petri, G.; Marinazzo, D.; Panzeri, S.; Brovelli, A.
10.1101/2024.09.23.614484 — neuroscience — Posted on 2024-09-24
1287 ALMS1 KO rat: a new model of metabolic syndrome with spontaneous hypertension
Jaykumar, A. B.; Monu, S. R.; Mendez, M.; Rhaleb, N.-E. B.; Ortiz, P. A.
10.1101/2024.09.22.614364 — physiology — Posted on 2024-09-24
1289 Tumor-induced endothelial RhoA activation mediates tumor cell transendothelial migration and metastasis
Sajib, M. S.; Zahra, F. T.; Lamprou, M.; Akwii, R. G.; Park, J. H.; Osorio, M.; Tullar, P.; Doci, C. L.; Zhang, C.; Huveneers, S.; van Buul, J. D.; Wang, M.-H.; Markiewski, M. M.; Srivastava, S. K.; Zheng, Y.; Gutkind, J. S.; Hu, J.; Bickel, U.; Maeda, D. Y.; Zebala, J. A.; Lionakis, M. S.; Trasti, S.; Mikelis, C. M.
10.1101/2024.09.22.614304 — physiology — Posted on 2024-09-24
1292 Revisiting sour rot of grapevine through disease-associated microbiomes: a tripartite co-infection?
Hevin, S.; Wilhelm, M.; Kehrli, P.; Buyck, B.; Gindro, K.; Wolfender, J.-L.; Hofstetter, V.
10.1101/2024.09.19.613941 — pathology — Posted on 2024-09-24
1293 Postmortem findings of free-ranging North American beavers (Castor canadensis) reveal potential threats to California freshwater ecosystems
Gonzales-Viera, O. A.; Woods, L. W.; Mete, A.; Fritz, H.; Armien, A.; Lantz, E.; Gomez-Puerta, L. A.; Famini, D.; Sherman, J.; Rudd, J. L.; Camp, L. E.; Shapiro, K.; Clifford, D. L.
10.1101/2024.09.21.614286 — pathology — Posted on 2024-09-24
1294 Comparative analysis of protein expression between oesophageal adenocarcinoma and normal adjacent tissue
Nicholas, B.; Bailey, A.; McCann, K. J.; Walker, R. C.; Johnson, P.; Elliott, T.; Underwood, T. J.; Skipp, P.
10.1101/2024.09.20.614054 — cancer biology — Posted on 2024-09-24
1295 The Role of ATP Synthase Subunit e (ATP5I) in Mediating the Metabolic and Antiproliferative Effects of Biguanides
Lefrancois, G.; Lavallee, E.; Rowell, M.-C.; Bourdeau, V.; Mohebali, F.; Berthomeu, T.; Tyers, M.; Gravel, S.-P.; Schmitzer, A. R.; Ferbeyre, G.
10.1101/2024.09.20.614047 — cancer biology — Posted on 2024-09-24
1307 Identification of potential inhibitors against Inosine 5'-Monophosphate Dehydrogenase of Cryptosporidium parvum through an integrated in silico approach
Al-Mamun, A.; Hossain, S. I.; Moin, A. T.; Rakib, M. S. I.; Hasan, M. M.; Yousuf, E. B.; Powshi, S. N.; Islam, E.; Tumpa, N. J. S.; Hosna, A.; Chowdhury, D. U. S.; Hossain, M.; Alam, S. S.; Islam, N.
10.1101/2024.09.22.614371 — bioinformatics — Posted on 2024-09-24
1314 Direct and ultrasensitive bioluminescent detection of intact respiratory viruses
Grawe, A.; van der Veer, H.; Jongkees, S. A. K.; Flipse, J.; Rossey, I.; de Vries, R. P.; Saelens, X.; Merkx, M.
10.1101/2024.09.22.614338 — bioengineering — Posted on 2024-09-24
1315 Established Sulfopeptide Tandem Mass Spectrometry Behavior and Sulfotransferase Assays Refute Tyrosine Sulfation as a Histone Mark
Youssef, M. M.; Szot, C. W.; Ayad, M. F.; Hussein, L. A.; Abdel-Ghany, M. F.; Bailey, R. C.; Mostafa, A. M.; Hakansson, K.
10.1101/2024.09.23.613127 — biochemistry — Posted on 2024-09-24
1317 The loss of a supergene in obligately polygynous Formica wood ant species
Sigeman, H.; Satokangas, I.; De Lamarre, M.; Deshmukh, R.; Nouhaud, P.; Helanterä, H.; Chapuisat, M.; Kulmuni, J.; Viljakainen, L.
10.1101/2024.09.20.613865 — genomics — Posted on 2024-09-24
1318 Transposable elements are prevalent vectors of transgenerational epigenetic inheritance in nature
Baduel, P.; De Oliveira, L.; Caillieux, E.; Bohl-Viallefond, G.; El Messaoudi, M.; Xu, C.; Barois, M.; Singh, V.; Sarazin, A.; Boccara, M.; Gilbault, E.; de France, A.; Quadrana, L.; Loudet, O.; Colot, V.
10.1101/2024.09.20.614076 — genomics — Posted on 2024-09-24
1319 Machine learning-optimized targeted detection of alternative splicing
Yang, K.; Islas, N.; Jewell, S.; Jha, A.; Radens, C. M.; Pleiss, J. A.; Lynch, K. W.; Barash, Y.; Choi, P. S.
10.1101/2024.09.20.614162 — genomics — Posted on 2024-09-24
1320 The molecular arsenal of the key coastal bioturbator Hediste diversicolor faced with changing oceans
Beine, K.; Feugere, L.; Fletcher, N.; Power, M. L.; Connell, L. J.; Bates, A.; Li, J.; Winter, M. R.; Sellers, G. S.; Mincarelli, L. F.; Vamos, S.; James, J.; Ohnstad, H.; Bartels-Hardege, H.; Parsons, D. R.; Sanders, T.; Parker, R.; Bolam, S. G.; Garcia, C.; Solan, M.; Hardege, J. D.; Godbold, J. A.; Wollenberg Valero, K. C.
10.1101/2024.09.20.614147 — genomics — Posted on 2024-09-24
1323 Functional impact of the hyperduplication genomophenotype in high copy number endometrial cancer
Florio, A.; Smadbeck, J.; Johnson, S.; Lin, W.-H.; Sadeghian, D.; Sotiriou, S.; Salvatori, R.; Feathers, R.; Berry, T.; Kinsella, L.; Harris, F.; McCune, A.; Murphy, S. J.; Ali, M.; Pezeshki, M.; Barrett, M. T.; Grcevich, L.; Capasso, I.; DeVitis, L. A.; Schivardi, G.; Occhiali, T.; Larish, A. M.; Weroha, J.; Borad, M. J.; Cheville, J.; Anastasiadis, P. Z.; Mariani, A.; Vasmatzis, G.
10.1101/2024.09.20.613693 — genomics — Posted on 2024-09-24
1327 A genome-wide CRISPR screen in Anopheles mosquito cells identifies essential genes and required components of clodronate liposome function
Mameli, E.; Samantsidis, G.-R.; Viswanatha, R.; Kwon, H.; Hall, D. R.; Butnaru, M.; Hu, Y.; Mohr, S. E.; Perrimon, N.; Smith, R. C.
10.1101/2024.09.24.614595 — genetics — Posted on 2024-09-24
1329 Ancient inversion polymorphisms are locally adaptive in a widespread butterfly species
Seixas, F. A.; Dendy, S.; Guan, S.; Rosser, N.; Grishin, N. V.; Davies, N.; Gilbert, L. E.; McMillan, O. W.; Mallet, J.
10.1101/2024.09.20.614156 — evolutionary biology — Posted on 2024-09-24
1331 Towards a global barcode reference library for subterranean fauna
Guzik, M. T.; Thornhill, J.; van der Heyde, M.; Stringer, D.; White, N.; Sacco, M.; Beasley-Hall, P. G.; King, R.; Nevill, P.; Cooper, S.; Austin, A.
10.1101/2024.09.20.613981 — evolutionary biology — Posted on 2024-09-24
1332 Plasticity in the pectoral fin skeleton is induced by altered foraging regime in a South American cichlid
Gilbert, M.; Kwiatkowski, A. J.; Woodburn, C. M.; Piggott, S. N.; Haridy, Y.; Aiello, B. R.; Albertson, R. C.; Stewart, T. A.
10.1101/2024.09.24.614498 — evolutionary biology — Posted on 2024-09-24
1334 Insights into the triggering factors and determination mechanisms of host alternation in aphids
Etier, A.; Ghosh, R.; Vericel, T.; Cloteau, R.; Denis, G.; Le Floch, M.; Outreman, Y.; Le-Trionnaire, G.; Simon, J.-C.
10.1101/2024.09.20.613903 — ecology — Posted on 2024-09-24
1336 Do pyrethroid insecticides influence sex ratios in agile frogs (Rana dalmatina)?
Balogh, E.; Hocza, S.; Ujhegyi, N.; Kasler, A.; Holly, D.; Herczeg, D.; Ujszegi, J.; Gal, Z.; Hoffmann, O. I.; Bokony, V.; Miko, Z.
10.1101/2024.09.21.614238 — ecology — Posted on 2024-09-24
1338 Covariation between metabolic and radioactive dose rates in Chornobyl rodents
Boratynski, Z.; Lavrinienko, A.; Lehmann, P.; Mousseau, T. A.; Tukalenko, E.; Vasylenko, A.; Watts, P. C.; Mappes, T.; Nowick, K.
10.1101/2024.09.20.614164 — ecology — Posted on 2024-09-24
1340 Toxicity of extracellular cGAMP and its analogs to T cells is due to SLC7A1-mediated import
Sudaryo, V.; R. Carvalho, D.; Lee, J. M.; Carozza, J. A.; Cao, X.; Cordova, A. F.; Li, L.
10.1101/2024.09.21.614248 — immunology — Posted on 2024-09-24
1342 Spatial programming of fibroblasts promotes resolution of tissue inflammation through immune cell exclusion
Reis Nisa, P.; Mahony, C.; Hackland, A.; Clay, E.; Chin, P.; Marsh, L.-J.; Bolton, C.; Kemble, S.; Smith, C. G.; Neag, G.; Singh, R.; Turner, J. D.; Filer, A.; Raza, K.; Richard, J.-B.; Midwood, K. S.; Buckley, C. D.; Wei, K.; McGettrick, H. M.; Coles, M.; Croft, A. P.
10.1101/2024.09.20.614064 — immunology — Posted on 2024-09-24
1343 Sex-specific decline in prefrontal cortex mitochondrial bioenergetics in aging baboons correlates with walking speed
Adekunbi, D. A.; Huber, H. F.; Benavides, G.; Tian, R.; Li, C.; Nathanielsz, P. W.; Zhang, J.; Darley-Usmar, V.; Cox, L. A.; Salmon, A. B.
10.1101/2024.09.19.613684 — physiology — Posted on 2024-09-24
1345 Structural Insights into the Role of the Proline Rich Region in Tau Function
Acosta, K.; Brue, C. R.; Kim, H. J.; Holubovska, P.; Mayne, L.; Murakami, K.; Rhoades, E.
10.1101/2024.09.20.614010 — biophysics — Posted on 2024-09-24
1346 Learning-Augmented Sketching Offers Improved Performance for Privacy Preserving and Secure GWAS
Xu, J.; Zhu, K.; Cai, J.; Kockan, C.; Dokmai, N.; Cho, H.; Woodruff, D.; Sahinalp, C.
10.1101/2024.09.19.613975 — bioinformatics — Posted on 2024-09-24
1348 Next-generation snow leopard population assessment tool: multiplex-PCR SNP panel for individual identification from feces
Solari, K. A.; Ahmad, S.; Armstrong, E. E.; Campana, M.; Ali, H.; Hameed, S.; Ullah, J.; Khan, B. U.; Nawaz, M. A.; Petrov, D. A.
10.1101/2024.09.19.613565 — genetics — Posted on 2024-09-24
1351 A Paradoxical Tumor Antigen Specific Response in the Liver
Trehan, R. S.; Zhu, X. B.; Huang, P.; Wang, X.; Soliman, M.; Strepay, D.; Nur, A.; Kedei, N.; Arhin, M.; Ghabra, S.; Rodriguez Matos, F.; Benmebarek, M.-R.; Ma, C.; Korangy, F.; Greten, T. F.
10.1101/2024.09.19.614002 — immunology — Posted on 2024-09-24
1353 Fasting is required for many of the benefits of calorie restriction in the 3xTg mouse model of Alzheimer&aposs disease
Babygirija, R.; Han, J. H.; Sonsalla, M. M.; Matoska, R.; Calubag, M. F.; Green, C. L.; Tobon, A.; Yeh, C.-Y.; Vertein, D.; Schlorf, S.; Illiano, J.; Liu, Y.; Grunow, I.; Rigby, M. J.; Puglielli, L.; Harris, D. A.; Denu, J. M.; Lamming, D. W.
10.1101/2024.09.19.613904 — physiology — Posted on 2024-09-24
1357 Selective targeting of TBXT with DARPins identifies regulatory networks and therapeutic vulnerabilities in chordoma
Umbaugh, C. S.; Groth, M.; Erkut, C.; Lee, K.-S.; Marinho, J.; Iser, F.; Kapp, J. N.; Schroeter, P.; Dolaner, S.; Kayserili, A.; Hartmann, J.; Walch, P.; Barth, T. F. E.; Mellert, K.; Dreier, B.; Schaefer, J. V.; Plueckthun, A.; Froehling, S.; Scholl, C.
10.1101/2024.09.20.614025 — cancer biology — Posted on 2024-09-24
1358 Constitutive expression of IκBζ promotes tumor growth and immunotherapy resistance in melanoma
Kolb, A.; Kulis-Mandic, A.-M.; Klein, M.; Stastny, A.; Haist, M.; Weidenthaler-Barth, B.; Sinnberg, T.; Sucker, A.; Allies, G.; Albrecht, L. J.; Tasdogan, A.; Tuettenberg, A.; Stege, H.; Schadendorf, D.; Grabbe, S.; Schulze-Osthoff, K.; Kramer, D.
10.1101/2024.09.19.613946 — cancer biology — Posted on 2024-09-24
1361 The use of 3D-printers as plotters opens up a new world in performing 2D migration analyses
Köppe, H.; Richert, M. G.; Singer, D.; Köppe, J.; Köppe, M.; Tzvetkov, M.; Schroeder, H. W. S.; Bekeschus, S.; Bien-Möller, S.
10.1101/2024.09.19.613824 — bioengineering — Posted on 2024-09-24
1362 In Situ UNIversal Orthogonal Network (UNION) Bioink Deposition for Direct Delivery of Corneal Stromal Stem Cells to Corneal Wounds
Brunel, L. G.; Cai, B.; Hull, S. M.; Han, U.; Wungcharoen, T.; Fernandes-Cunha, G. M.; Seo, Y. A.; Johansson, P. K.; Heilshorn, S. C.; Myung, D.
10.1101/2024.09.19.613997 — bioengineering — Posted on 2024-09-24
1363 Cardiovascular Disease-Associated Non-Coding Variants Disrupt GATA4-DNA Binding and Regulatory Functions
Pena-Martinez, E. G.; Messon-Bird, J. L.; Rodrlguez-Rlos, J. M.; Velazquez-Roig, R.; Pomales-Matos, D. A.; Rivera-Madera, A.; Sanabria-Alberto, L.; Barreiro-Rosario, A. C.; Rivera-Del Valle, J.; Munoz-Paez, N. E.; Peterson-Peguero, E. A.; Rodriguez-Martinez, J. A.
10.1101/2024.09.19.613959 — genomics — Posted on 2024-09-24
1367 habtools: an R package to calculate 3D metrics for surfaces and objects
Schiettekatte, N. M.; Asbury, M.; Chen, G.-Y.; Dornelas, M.; Reichert, J.; Torres-Pulliza, D.; Zawada, K. J.; Madin, J. S.
10.1101/2024.09.19.613985 — ecology — Posted on 2024-09-24
1371 Horizontally transferred cell-free chromatin particles function as autonomous predatory genomes and vehicles for transposable elements within host cells
Banerjee, S.; Shende, S.; Kata, L.; Lopes, R.; Praveen, S.; Joshi, R.; Khare, N. K.; Raghuram, G. V.; Shabrish, S.; Mittra, I.
10.1101/2023.11.21.567988 — evolutionary biology — Posted on 2024-09-24
1374 Cleaning the Dead: Optimized decontamination enhances palaeoproteomic analyses of Pleistocene skeletal material
Fagernäs, Z.; Villa Islas, V.; Troche, G.; Buylaert, J.-P.; Khujageldiev, T.; Kurbanov, R.; Olsen, J. V.; Pedersen, M. W.; Welker, F.
10.1101/2024.06.13.598810 — evolutionary biology — Posted on 2024-09-24
1375 The fetal specific gene LIN28B is essential for human fetal B-lymphopoiesis and initiation of KMT2A::AFF1 infant leukemia
Ling, R. E.; Jackson, T.; Elliott, N.; Cross, J. W.; Hamer, L.; Wuppalapati, A.; Smith, A.; Chahrour, C. M.; Sevim, O.; Iskander, D.; Wang, G.; Rice, S.; O'Bryne, S.; Harman, J. R.; Psaila, B.; Morgan, R. G.; Roberts, I.; Milne, T. A.; Roy, A.
10.1101/2024.09.18.613730 — cancer biology — Posted on 2024-09-24
1376 Comprehensive proteolytic profiling of Aedes aegypti mosquito midgut extracts: Unraveling the blood meal protein digestion system
O'Donoghue, A. J.; Lui, C.; Simington, C. J.; Montermoso, S.; Moreno-Galvez, E.; Serafim, M. S. M.; Burata, O. E.; Lucero, R. M.; Nguyen, J. T.; Fong, D.; Tran, K.; Millan, N.; Gallimore, J. M.; Parungao, K. A.; Fong, J.; Suzuki, B. M.; Jiang, Z.; Isoe, J.; Rascon, A. A.
10.1101/2024.09.23.614410 — biochemistry — Posted on 2024-09-24
1377 Identification of neurodevelopmental organization of the cell populations of juvenile Huntington's disease using dorso-ventral HD organoids and HD mouse embryos
Switonska-Kurkowska, K.; Kubis, J.; Delimata-Raczek, J.; Krist, B.; Surdyka, M.; Kalinowska-Poska, Z.; Piasecki, P.; Handschuh, L.; Podkowinski, J.; Rakoczy, M.; Samelak-Czajka, A.; Hayden, M. R.; Caron, N. S.; Figiel, M.
10.1101/2024.09.23.614496 — developmental biology — Posted on 2024-09-24
1378 Environmental sphagnum-associated fungi target thiol homeostasis to compete with Mycobacterium tuberculosis.
Malhotra, N.; Oh, S.; Finin, P.; Medrano, J.; Andrews, J.; Goodwin, M.; Markowitz, T. E.; Lack, J.; Boshoff, H. I. M.; Barry, C.
10.1101/2024.09.23.614403 — microbiology — Posted on 2024-09-24
1382 A minor impact of VGLUT1 expression level on quantal size revealed through the characterization of VGLUT1mEos2 knock-down new mouse model
Zhang, X. M.; Francois, U.; Angelo, M. F.; Claverol, S.; Mondin, M.; Martin, C.; Deshors, M.; Humeau, Y.; Lipstein, N.; Herzog, E.
10.1101/2024.09.23.614439 — neuroscience — Posted on 2024-09-24
1384 Evaluating Physiological Indicators in Detecting Deception and Truthfulness using theComparison Question Test (CQT)
Rashid, A. M. S.; Carmichael, B.; Su, C.; Shi, K.; Lim, K.; Kumar, P. S.; Wan, N. J.; Govil, E.; Yap, D.
10.1101/2024.09.01.609623 — bioengineering — Posted on 2024-09-24
1385 AyurPhenoClusters define common molecular roots for rare diseases and uncover ciliary dysfunctions in syndromic conditions
Joshi, A.; Jangir, D.; Sharma, A.; Anand, T.; Verma, H.; Yadav, M.; Rangani, N.; Joshi, P.; Singh, R. P.; Kumar, S.; Girdhar, S.; Sharma, R.; Kumar, A.; Dey, L.; Mukerji, M.
10.1101/2024.09.13.612844 — genetics — Posted on 2024-09-24
1387 The functional roles of zebrafish HoxA- and HoxD-related clusters in the pectoral fin development
Ishizaka, M.; Maeno, A.; Nakazawa, H.; Fujii, R.; Oikawa, S.; Tani, T.; Kanno, H.; Koita, R.; Kawamura, A.
10.1101/2024.07.05.600788 — developmental biology — Posted on 2024-09-24
1392 Cholinergic Neuronal Activity Promotes Diffuse Midline Glioma Growth through Muscarinic Signaling
Drexler, R.; Drinnenberg, A.; Gavish, A.; Yalcin, B.; Shamardani, K.; Rogers, A.; Mancusi, R.; Taylor, K. R.; Kim, Y. S.; Woo, P. J.; Ravel, A.; Tatlock, E.; Ramakrishnan, C.; Ayala-Sarmiento, A. E.; Rincon Fernandez Pacheco, D.; Siverts, L.; Daigle, T. L.; Tasic, B.; Zeng, H.; Breunig, J.; Deisseroth, K.; Monje, M.
10.1101/2024.09.21.614235 — neuroscience — Posted on 2024-09-24
1393 Energy Aware Technology Mapping of Genetic Logic Circuits
Kubaczka, E.; Gehri, M.; Marlhens, J. J. M.; Schwarz, T.; Molderings, M.; Engelmann, N.; Garcia, H. G.; Hochberger, C.; Koeppl, H.
10.1101/2024.06.27.601038 — synthetic biology — Posted on 2024-09-24
1394 CRISPR-Cas-based Microhomology-Mediated End Joining for Precise Gene Replacement in Plant
Vu, T. V.; Lim, G.-H.; Choi, S. H.; Moon, J. Y.; Nguyen, N. T.; Das, S.; Tran, M. T.; Sung, Y. W.; Kim, J.; Song, Y. J.; Kim, S. W.; Jeong, J. C.; Kim, J.-Y.
10.1101/2022.08.27.505510 — synthetic biology — Posted on 2024-09-24
1395 Distinct duration and diet dependent lipid profiles and renal complicationsin GCK-MODY
Huang, Y.; Fan, Y.; Liu, Y.; Liu, X.; Li, W.; Yang, Y.; Zhang, Z.; Ma, S.; shuhui, j.; Chen, S.; Shu, H.; Feng, W.; Wang, K.; He, Q.; Qi, W.; Fan, Y.; Li, X.; Liu, M.
10.1101/2024.09.17.613598 — physiology — Posted on 2024-09-24
1396 Learning precise segmentation of neurofibrillary tangles from rapid manual point annotations
Ghandian, S.; Albarghouthi, L.; Nava, K.; Sharma, S. R. R.; Minaud, L.; Beckett, L.; Saito, N.; DeCarli, C.; Rissman, R. A.; Teich, A. F.; Jin, L.-W.; Dugger, B. N.; Keiser, M. J.
10.1101/2024.05.15.594372 — pathology — Posted on 2024-09-24
1398 High WEE1 expression is independently linked to poor survival in multiple myeloma
Simhal, A. K.; Firestone, R. S.; Oh, J. H.; Avutu, V.; Norton, L.; Hultcrantz, M.; Usmani, S. Z.; Maclachlan, K. H.; Deasy, J. O.
10.1101/2024.09.20.613788 — cancer biology — Posted on 2024-09-24
1399 Hyperdisordered cell packing on a growing surface
Ross, R. J. H.; Masucci, G. D.; Lin, C. Y.; Iglesias, T. L.; Reiter, S.; Pigolotti, S.
10.1101/2024.05.20.593453 — biophysics — Posted on 2024-09-24
1400 Pangenome-Informed Language Models for Privacy-Preserving Synthetic Genome Sequence Generation
Huang, P.; Charton, F.; Schmelzle, J.-N. M.; Darnell, S. S.; Prins, P.; Garrison, E.; Suh, G. E.
10.1101/2024.09.18.612131 — bioinformatics — Posted on 2024-09-24
1401 Differential quantification of alternative splicing events on spliced pangenome graphs
Ciccolella, S.; Cozzi, D.; Della Vedova, G.; Kuria, S.; Bonizzoni, P.; Denti, L.
10.1101/2023.11.06.565751 — bioinformatics — Posted on 2024-09-24
1405 The fate of pyruvate dictates cell growth by modulating cellular redox potential
Toshniwal, A. G.; Lam, G.; Bott, A. J.; Cluntun, A.; Nam, H.-J.; Skabelund, R.; Wisidagama, D. R.; Thummel, C. S.; Rutter, J.
10.1101/2024.09.23.614588 — cell biology — Posted on 2024-09-24
1406 Prophages are Infrequently Associated With Antibiotic Resistance in Pseudomonas aeruginosa Clinical Isolates
Chang, T. H.; Pourtois, J.; Haddock, N.; Furkuawa, D.; Kelly, K. E.; Amanatullah, D.; Burgener, E. B.; Milla, C.; Banaei, N.; Bollyky, P.
10.1101/2024.06.02.595912 — microbiology — Posted on 2024-09-24
1408 Droplet Sequencing Reveals Virulence Gene Clusters in Oral Biofilm Extracellular Vesicles
Takano, S.; Takenawa, S.; Divya, N.; Kangmin, Y.; Maehara, T.; Nomura, N.; Obana, N.; Toyofuku, M.; Usui, M.; Ariyoshi, W.; Okamoto, A.
10.1101/2024.09.18.613607 — microbiology — Posted on 2024-09-24
1409 A dual-pathway architecture enables chronic stress to disrupt agency and promote habit formation
Giovanniello, J. R.; Paredes, N.; Wiener, A.; Ramirez-Armenta, K.; Oragwam, C.; Uwadia, H. O.; Yu, A. L.; Lim, K.; Pimenta, J. S.; Vilchez, G. E.; Nnamdi, G.; Wang, A.; Sehgal, M.; Reis, F. M.; Sias, A. C.; Silva, A. J.; Adhikari, A.; Malvaez, M.; Wassum, K. M.
10.1101/2023.10.03.560731 — neuroscience — Posted on 2024-09-24
1411 Hippocampal γCaMKII dopaminylation promotes synaptic-to-nuclear signaling and memory formation
Stewart, A. F.; Fulton, S. L.; Durand-de Cuttoli, R.; Thompson, R. E.; Chen, P.-J.; Brindley, E.; Cetin, B.; Farrelly, L. A.; Futamura, R.; Claypool, S.; Bastle, R. M.; Di Salvo, G.; Peralta, C.; Molina, H.; Baljinnyam, E.; Marro, S. G.; Russo, S. J.; Devita, R. J.; Muir, T. W.; Maze, I.
10.1101/2024.09.19.613951 — neuroscience — Posted on 2024-09-24
1414 Explore the mechanism of Zigui Yichong Formula in reducing the apoptosis of ovarian granulosa cells in premature ovarian insufficiency based on network pharmacology, molecular docking and cell experiments
Zhang, X.; Zhang, X.-M.; Xi, H.-Y.; Gao, T.-Y.; Liu, S.-P.; Li, R.-X.; Hongyan Xi Co-first authorRongxoa Li Corresponding author Tianyu Gao Second auther Shupeng Liu Thi,
10.1101/2024.09.21.614279 — pharmacology and toxicology — Posted on 2024-09-24
1419 Galvanin is an electric-field sensor for directed cell migration
Belliveau, N. M.; Footer, M. J.; Platenkamp, A.; Kim, H.; Eustis, T. E.; Theriot, J. A.
10.1101/2024.09.23.614580 — cell biology — Posted on 2024-09-24
1420 Innate immune epigenomic landscape following controlled human influenza virus infection
Thistlethwaite, W.; Vangeti, S.; Cheng, W.-S.; Agarwal, P.; Cappuccio, A.; Wang, W.; Wei, B.; Myers, R.; Rubenstein, A. B.; Chawla, D.; Hariharan, M.; McClain, M. T.; Burke, T. W.; Kleinstein, S. H.; Ecker, J. R.; Woods, C. W.; Greenleaf, W. J.; Chen, X.; Ramos, I.; Zaslavsky, E.; Evans, T. G.; Troyanskaya, O. G.; Sealfon, S. C.
10.1101/2024.09.20.612974 — immunology — Posted on 2024-09-24
1423 Disparate demographic impacts of the Roman Colonization and the Migration Period in the Iberian Peninsula.
Carrion, P.; Olalde, I.; Jimenez-Arenas, J. M.; Coromina, N.; Vivo, D.; Verges, J. M.; Costa, A.; Botella, D.; Bustamante-Alvarez, M.; Heras-Mora, J.; Ortega-Ruiz, R.; Chaves, C.; Garcia-Collado, M. I.; Quiros-Castillo, J.; Roig, J.; Suarez-Padilla, J.; Navarro-Luengo, I.; Cuadrado, M. A.; Aguilera, I.; Morera, J.; Catalan, R.; Cerdeno, M. L.; Roig-Perez, J. F.; Diaz-Garcia, M.; Chirosa-Canavate, P.; Piza-Ruiz, T.; Vallejo-Casas, E.; Vidal-Alvarez, S.; Burch, J.; Sagrera, J.; Vivo, J.; Cubo-Cordoba, A.; Martinez-Enamorado, V.; Rengel-Castro, F.; Garcia-Entero, V.; Rodero, A.; Viguera, E.; Rohl
10.1101/2024.09.23.614606 — genomics — Posted on 2024-09-23
1424 GABAergic neuron dysregulation in a human neurodevelopmental model for major psychiatric disorders
Guo, Z.; Su, Y.; Huang, W.-k.; Yao, X. S.; Hong, Y.; Gordin, A.; Nguyen, H. N.; Wen, Z.; Ringeling, F. R.; Chen, G.; Li, S.; Lu, L.; Xia, M.; Zheng, W.; Sawa, A.; Chen, G.; Christian, K. M.; Song, H.; Ming, G.-L.
10.1101/2024.09.23.614564 — neuroscience — Posted on 2024-09-23
1425 Adrenergic signaling gates astrocyte responsiveness to neurotransmitters and control of neuronal activity
Guttenplan, K. A.; Maxwell, I.; Santos, E.; Borchardt, L. A.; Manzo, E.; Abalde-Atristain, L.; Kim, R. D.; Freeman, M. R.
10.1101/2024.09.23.614537 — neuroscience — Posted on 2024-09-23
1426 Mother-child dyadic interactions shape children's social brain and theory of mind
Li, L.; Xiao, J.; Zhao, W.; Zheng, Q.; Huang, X.; Shan, X.; Ming, Y.; Wang, P.; Wu, Z.; Chen, H.; Menon, V.; Duan, X.
10.1101/2024.09.23.614623 — neuroscience — Posted on 2024-09-23
1427 Hippocampal representations of alternative possibilities are flexibly generated to meet cognitive demands
Comrie, A. E.; Monroe, E. J.; Kahn, A. E.; Denovellis, E. L.; Joshi, A.; Guidera, J. A.; Krausz, T. A.; Berke, J. D.; Daw, N. D.; Frank, L. M.
10.1101/2024.09.23.613567 — neuroscience — Posted on 2024-09-23
1429 Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells
Graham, J. P.; Castro, J. G.; Werba, L. C.; Fardone, L. C.; Francis, K. P.; Ramamurthi, A.; Layden, M.; McCarthy, H. O.; Gonzalez-Fernandez, T.
10.1101/2024.09.23.614499 — bioengineering — Posted on 2024-09-23
1430 Cytotoxicity of Activator Expression in CRISPR-based Transcriptional Activation Systems
Maddineni, A.; Liang, Z.; Jambardi, S.; Roy, S.; Tycko, J.; Patil, A.; Manzano, M.; Gottwein, E.
10.1101/2024.09.23.614524 — molecular biology — Posted on 2024-09-23
1431 CHAMP1 complex directs heterochromatin assembly and promotes homology-directed DNA repair
D'Andrea, A. D.; Li, F.; Zhang, T.; Syed, A.; Elbakry, A.; Holmer, N.; Nguyen, H.; Mukkavalli, S.; Greenberg, R. A.
10.1101/2024.09.23.614480 — molecular biology — Posted on 2024-09-23
1432 A Novel Adhesin of B. pertussis is Key to Colonisation of Epithelial Cells
Gollan, M.; Gestal, M. C.; Parrish, K. M.; Harvill, E. T.; Preston, A.; MacArthur, I.
10.1101/2024.09.23.613229 — microbiology — Posted on 2024-09-23
1433 Elucidation of the glycan structure of the b-type flagellin of Pseudomonas aeruginosa PAO1
Hensbergen, P. J.; van Huijkelom, L.; van Angeren, J.; de Ru, A. H.; Claushuis, B.; van Veelen, P. A.; Smits, W. K.; Corver, J.
10.1101/2024.09.23.614423 — microbiology — Posted on 2024-09-23
1435 CLCC1 promotes membrane fusion during herpesvirus nuclear egress.
Dai, B.; Polack, L.; Sperl, A.; Dame, H.; Huynh, T.; Deveney, C.; Lee, C.; Doench, J. G.; Heldwein, K. E.
10.1101/2024.09.23.614151 — microbiology — Posted on 2024-09-23
1436 Targeting the host transcription factor HSF1 prevents human cytomegalovirus replication in vitro and in vivo
Biswas, J.; Akter, D.; Miller, M. J.; Thiele, D. J.; Murphy, E. A.; O'Connor, C.; Moffat, J. F.; Chan, G.
10.1101/2024.09.23.614483 — microbiology — Posted on 2024-09-23
1442 Human untargeted metabolomics in the gut microbiome era: ethanol vs methanol
Zuffa, S.; Charron-Lamoureux, V.; Brennan, C.; Ambre, A.; Knight, R.; Dorrestein, P. C.
10.1101/2024.09.23.614605 — biochemistry — Posted on 2024-09-23
1443 An integrative modelling approach to the mitochondrial cristae
Brown, C. M.; Westendorp, M. S. S.; Zarmiento-Garcia, R.; Stevens, J. A.; Rouse, S. L.; Marrink, S.-J.; Wassenaar, T. A.
10.1101/2024.09.23.613389 — biochemistry — Posted on 2024-09-23
1445 Structural Basis for Antibody Neutralization of Pertussis Toxin
Goldsmith, J. A.; Nguyen, A. W.; Wilen, R. E.; Wijagkanalan, W.; McLellan, J. S.; Maynard, J. A.
10.1101/2024.09.23.614357 — biochemistry — Posted on 2024-09-23
1446 Protein Language Models: Is Scaling Necessary?
Fournier, Q.; Vernon, R. M.; van der Sloot, A.; Schulz, B.; Chandar, S.; Langmead, C. J.
10.1101/2024.09.23.614603 — molecular biology — Posted on 2024-09-23
1447 MTALTCO1: a 259 amino acid long mtDNA-encoded alternative protein that challenges conventional understandings of mitochondrial genomics.
Robitaille, F.; Ben Hadj, A.; Campbell, A.; Nadeau-Lachance, L.; Niaison, T.; Choquette, T.; Roucou, X.; Angers, A.; Breton, S.
10.1101/2024.09.22.614361 — molecular biology — Posted on 2024-09-23
1449 TNFSF13 insufficiency disrupts human colonic epithelial cell-mediated B cell differentiation
Ma, X.; Dawany, N.; Kondo, A.; Maurer, K.; Karakasheva, T.; Shraim, R.; Williams, P. A.; Parham, L. R.; Simon, L. A.; Danan, C. H.; Conrad, M. A.; Piccoli, D. A.; Devoto, M.; Sullivan, K. E.; Kaestner, K. H.; Kelsen, J. R.; Hamilton, K. E.
10.1101/2024.09.23.614260 — molecular biology — Posted on 2024-09-23
1450 Pythia: Non-random DNA repair allows predictable CRISPR/Cas9 integration and gene editing
Naert, T.; Yamamoto, T.; Han, S.; Horn, M.; Bethge, P.; Vladimirov, N.; Voigt, F.; Figueiro-Silva, J.; Bachmann-Gagescu, R.; Helmchen, F.; Lienkamp, S. S.
10.1101/2024.09.23.614424 — molecular biology — Posted on 2024-09-23
1452 Neuroinvasive and neurovirulent potential of SARS-CoV-2 in the acute and post-acute phase of intranasally inoculated ferrets
Benavides, F. F. W.; Kroeze, E. J. B. V.; Leijten, L. M.; Schmitz, K. S.; van Run, P.; Kuiken, T.; de Vries, R. D.; Bauer, L.; van Riel, D.
10.1101/2024.09.21.614276 — microbiology — Posted on 2024-09-23
1453 Protection against necrotizing enterocolitis by fecal filtrate transfer requires an active donor virome
Spiegelhauer, M. R.; Margaard Offersen, S.; Mao, X.; Gambino, M.; Nielsen, D. S.; Nguyen, D. N.; Brunse, A.
10.1101/2024.09.23.614450 — microbiology — Posted on 2024-09-23
1455 Genetic and microbial analysis of invasiveness for Escherichia coli strains associated with inflammatory bowel disease
Kim, J.; Zhang, J.; Kinch, L. N.; Shen, J.; Field, S.; Klapproth, J.-M.; Forsberg, K. J.; Harris-Tryon, T. A.; Orth, K. A.; Cong, Q.; Ni, J.
10.1101/2024.09.23.613251 — microbiology — Posted on 2024-09-23
1457 The exopolysaccharide Poly-N-Acetyl-Glucosamine (PNAG) coats Klebsiella pneumoniae in vivo
Bradshaw, J.; Sanchez-Garrido, J.; Berkachy, R.; Rattle, J.; Preston, C.; Pizza, M.; Ros, I. M.; Romano, M. R.; Wong, J.; Frankel, G.
10.1101/2024.09.23.614408 — microbiology — Posted on 2024-09-23
1461 In planta transposon sequencing for virulence gene identification in Xylella fastidiosa
Burbank, L. P.; Deyett, E.; Her, N.; Helm Rodriguez, S.; Magdeleno, M.; Rolshausen, P.; Roper, M. C.
10.1101/2024.09.23.614259 — microbiology — Posted on 2024-09-23
1464 Machine Learning Driven Simulations of SARS-CoV-2 Fitness Landscape
Durumeric, A. E. P.; Koehler, J.; Elez, K.; Raich, L.; Suriana, P. A.; Sztain, T.
10.1101/2024.09.20.614179 — bioinformatics — Posted on 2024-09-23
1465 Spatial multi-omics reveal intratumoral humoral immunity niches associated with tertiary lymphoid structures in pancreatic cancer immunotherapy pathologic responders
Sidiropoulos, D. N.; Shin, S. M.; Wetzel, M.; Girgis, A. A.; Bergman, D.; Danilova, L.; Perikala, S.; Shu, D. H.; Montagne, J. M.; Deshpande, A.; Leatherman, J.; Dequiedt, L.; Jacobs, V.; Ogurtsova, A.; Mo, G.; Yuan, X.; Lvovs, D.; Stein-O'Brien, G.; Yarchoan, M.; Zhu, Q.; Harper, E. I.; Weeraratna, A. T.; Kiemen, A. L.; Jaffee, E. M.; Zheng, L.; Ho, W. J.; Anders, R. A.; Fertig, E. J.; Kagohara, L. T.
10.1101/2024.09.22.613714 — cancer biology — Posted on 2024-09-23
1466 Integrative modeling in the age of machine learning: a summary of HADDOCK strategies in CAPRI rounds 47-55
Reys, V.; Giulini, M.; Cojocaru, V.; Engel, A. L.; Xu, X.; Roel-Touris, J.; Geng, C.; Ambrosetti, F.; Jimenez-Garcia, B.; Jandova, Z.; Koukos, P. I.; van Noort, C. W.; Teixeira, J. M. C.; van Keulen, S. C.; Reau, M.; Honorato, R. V.; Bonvin, A. M. J. J.
10.1101/2024.09.16.613212 — bioinformatics — Posted on 2024-09-23
1467 Ferroptosis Integrates Mitochondrial Derangements and Pathological Inflammation to Promote Pulmonary Hypertension
Kazmirczak, F.; Vogel, N. T.; Prisco, S.; Patterson, M. T.; Annis, J.; Moon, R. T.; Hartweck, L. M.; Mendelson, J. B.; Kim, M.; Laixto Mancripe, N.; Markowski, T.; Higgins, L.; Guerrero, C.; Kremer, B.; Blake, M.; Rhodes, C. J.; Williams, J. W.; Brittain, E. L.; Prins, K.
10.1101/2023.01.19.524721 — biochemistry — Posted on 2024-09-23
1468 Temporal misexpression of En1 during limb development causes distinct phenotypes
Ringel, A. R.; Magg, A.; Benetti, N.; Schoepflin, R.; Kuehnlein, M. N.; Stiege, A. C.; Fischer, U.; Wittler, L.; Lorenz, S.; Mundlos, S.; Allou, L.
10.1101/2024.08.06.606766 — developmental biology — Posted on 2024-09-23
1469 Cell signaling facilitates apical constriction by basolaterally recruiting Arp2/3 via Rac and WAVE
Zhang, P.; Medwig-Kinney, T. N.; Breiner, E. A.; Perez, J. M.; Song, A. N.; Goldstein, B.
10.1101/2024.09.23.614059 — cell biology — Posted on 2024-09-23
1470 BCR ligation selectively inhibits IgE class switch recombination
Wade-Vallance, A. K.; Yang, Z.; Libang, J. B.; Krishnapura, A. R.; Jung, J. B.; Matcham, E. W.; Robinson, M. J.; Allen, C. D. C.
10.1101/2024.09.18.613749 — immunology — Posted on 2024-09-23
1477 Fast-twitch myofibrils grow in proportion to Mylpf dosage in the zebrafish embryo
Adekeye, T. E.; Teets, E. M.; Tomak, E. A.; Waterman, S. L.; Sprague, K. A.; White, A.; Coffin, M. L.; Varga, S. M.; Easterbrooks, T. E.; Shepherd, S. J.; Austin, J. D.; Krivorotko, D.; Hupper, T. E.; Kelley, J. B.; Amacher, S. L.; Talbot, J. C.
10.1101/2024.09.18.613721 — developmental biology — Posted on 2024-09-23
1480 Predicting Primary Graft Dysfunction in Lung Transplantation: Machine Learning-Guided Biomarker Discovery
Nord, D.; Brunson, J. C.; Langerude, L.; Moussa, H.; Gill, B.; Machuca, T.; Rackauskas, M.; Sharma, A. K.; Lin, C.; Emtiazjoo, A.; Atkinson, C.
10.1101/2024.05.24.595368 — immunology — Posted on 2024-09-23
1481 hiPSC-derived astrocytes from individuals with schizophrenia promote alterations in phagocytosis and chemotaxis of microglial-like cells
Cardozo, P. L.; Lee, C.-Y.; Lacerda, J. P. S.; Fahel, J. S.; Trindade, P.; Vitoria, G.; Chicaybam, L.; Cordeiro, R. C.; de Faria, I. J. S.; Silva, N. C.; Todjro, Y. M. H.; Maciel, J. C. d. P.; Bonamino, M. H.; Vieira, L. B.; Cruz, B. F.; Nicolato, R.; Brennand, K. J.; Rehen, S. K.; Ribeiro, F. M.
10.1101/2024.09.20.614161 — neuroscience — Posted on 2024-09-23
1482 The Circadian Neuropeptide PDF has Sexually Dimorphic Effects on Activity Rhythms
Iyer, A. R.; Scholz-Carlson, E.; Bell, E.; Biondi, G.; Richhariya, S.; Fernandez, M. P.
10.1101/2024.01.31.578273 — neuroscience — Posted on 2024-09-23
1487 Defining the heterogeneous molecular landscape of lung cancer cell responses to epigenetic inhibition
Lin, C.; Sniezek, C. M.; McGann, C. D.; Karki, R.; Giglio, R. M.; Garcia, B. A.; McFaline-Figueroa, J. L.; Schweppe, D. K.
10.1101/2024.05.23.592075 — cancer biology — Posted on 2024-09-23
1490 Prediction and functional interpretation of inter-chromosomal genome architecture from DNA sequence with TwinC
Jha, A.; Hristov, B.; Wang, X.; Wang, S.; Greenleaf, W.; Kundaje, A.; Aiden, E. L.; Bertero, A.; Noble, W. S.
10.1101/2024.09.16.613355 — bioinformatics — Posted on 2024-09-23
1491 Epiregulon: Inference of single-cell transcription factor activity to predict drug response and drivers of cell state
Wlodarczyk, T.; Lun, A.; Wu, D.; Shi, M.; Ye, X.; Menon, S.; Toneyan, S.; Seidel, K.; Wang, L.; Tan, J.; Chen, S.-Y.; Keyes, T.; Chlebowski, A.; Waddell, A.; Zhou, W.; Wang, Y.; Yuan, Q.; Guo, Y.; Chen, L.-F.; Daniel, B.; Hafner, A.; He, M.; Chibly, A.; Liang, Y.; Duren, Z.; Metcalfe, C.; Hafner, M.; Siebel, C. W.; Corces, M. R.; Yauch, R.; Xie, S.; Yao, X.
10.1101/2023.11.27.568955 — bioinformatics — Posted on 2024-09-23
1495 Trends in genome diversity of small populations under a conservation program: a case study of two French chicken breeds
Bortoluzzi, C.; Restoux, G.; Rouger, R.; Desnoues, B.; Petitjean, F.; Bosse, M.; Tixier-Boichard, M.
10.1101/2024.02.22.581528 — genomics — Posted on 2024-09-23
1497 The theory of massively repeated evolution and full identifications of Cancer Driving Nucleotides (CDNs)
Zhang, L.; Deng, T.; Liufu, Z.; Liu, X.; Chen, B.; Hu, Z.; Liu, C.; Lu, X.; Tracy, M. E.; Wen, H.-J.; Wu, C.-I.
10.1101/2024.05.29.596366 — evolutionary biology — Posted on 2024-09-23
1498 Neuroendocrine Control of Intestinal Regeneration Through the Vascular Niche in Drosophila.
Medina, A.; Perochon, J.; Johnson, C.; Polcownuk, S.; Tian, Y.; Yu, Y.; Cordero, J. B.
10.1101/2024.09.10.612352 — developmental biology — Posted on 2024-09-23
1499 The G-Protein Couple Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis
Asensio, A.; Sanz-Flores, M.; Liakath-Ali, K.; Palacios, J.; Paramio, J. M.; Garcia-Escudero, R.; Mayor, F.; Ribas, C.
10.1101/2024.04.11.589052 — cell biology — Posted on 2024-09-23
1502 Bnip3lb-driven mitophagy sustains expansion of the embryonic hematopoietic stem cell pool
Meader, E.; Walcheck, M. T.; Leder, M. R.; Jing, R.; Wrighton, P. J.; Sugden, W. W.; Najia, M. A.; Oderberg, I. M.; Taylor, V. M.; LeBlanc, Z. C.; Quenzer, E. D.; Lim, S.-E.; Daley, G. Q.; Goessling, W.; North, T. E.
10.1101/2024.09.23.614531 — cell biology — Posted on 2024-09-23
1503 AKT-mediated phosphorylation of TSC2 controls stimulus and tissue-specific mTORC1 signaling and organ growth
Cormerais, Y.; Lapp, S. C.; Kalafut, K. C.; Cisse, M. Y.; Shin, J.; Stefadu, B.; Personnaz, J.; Schrotter, S.; D'Amore, A.; Martin, E. R.; Salussolia, C. L.; Sahin, M.; Menon, S.; Byles, V.; Manning, B. D.
10.1101/2024.09.23.614519 — cell biology — Posted on 2024-09-23
1506 NEURD offers automated proofreading and feature extraction for connectomics
Celii, B.; Papadopoulos, S.; Ding, Z.; Fahey, P. G.; Wang, E.; Papadopoulos, C.; Kunin, A.; Patel, S.; Bae, J. A.; Bodor, A. L.; Brittain, D.; Buchanan, J.; Bumbarger, D. J.; Castro, M. A.; Cobos, E.; Dorkenwald, S.; Elabbady, L.; Halageri, A.; Jia, Z.; Jordan, C.; Kapner, D.; Kemnitz, N.; Kinn, S.; Lee, K.; Li, K.; Lu, R.; Macrina, T.; Mahalingam, G.; Mitchell, E.; Mondal, S. S.; Mu, S.; Nehoran, B.; Popovych, S.; Schneider-Mizell, C. M.; Silversmith, W.; Takeno, M.; Torres, R.; Turner, N. L.; Wong, W.; Wu, J.; Yu, S.-c.; Yin, W.; Xenes, D.; Kitchell, L. M.; Rivlin, P. K.; Rose, V. A.; Bishop
10.1101/2023.03.14.532674 — neuroscience — Posted on 2024-09-23
1507 Single cell landscape of sex differences in the progression of multiple sclerosis
Soler-Saez, I.; Gomez-Cabanes, B.; Grillo-Risco, R.; Galiana-Rosello, C.; Barea-Moya, L.; Carceller, H.; de la Iglesia-Vaya, M.; Gil-Perotin, S.; Tepavcevic, V.; Hidalgo, M. R.; Garcia-Garcia, F.
10.1101/2024.06.15.599139 — neuroscience — Posted on 2024-09-23
1509 Recovery of the full in vivo firing range in post-lesion surviving DA SN neurons associated with Kv4.3-mediated pacemaker plasticity
Kovacheva, L.; Shin, J.; Diez de Bonilla, J. Z.; Mankel, J.; Farassat, N.; Costa, K. M.; Thakur, P.; Obeso, J.; Roeper, J.
10.1101/2021.08.09.455657 — neuroscience — Posted on 2024-09-23
1510 DNMT1-Mediated Regulation of Inhibitory Interneuron Migration Impacts Cortical Architecture and Function
Reichard, J.; Wolff, P.; Du, J.; Fullio, C. L.; Dorp, L.; Yildiz, C. B.; Linde, J.; Vollmer, J.; Kempf, S.; Graff, S.; Nabbefeld, G.; Singh, M.; Kuo, C.-C.; Mohan, N. K.; Vogel, T.; Musall, S.; Zimmer-Bensch, G. M.
10.1101/2024.09.04.611268 — neuroscience — Posted on 2024-09-23
1513 GnRH pulse generator activity in mouse models of polycystic ovary syndrome
Zhou, Z.; Han, S. Y.; Pardo-Navarro, M.; Wall, E. G.; Desai, R.; Vas, S.; Handelsman, D. J.; Herbison, A.
10.1101/2024.06.04.597387 — neuroscience — Posted on 2024-09-23
1516 Taxonomy, nomenclature, and identification of the giant hummingbirds (Patagona spp.) (Aves: Trochilidae)
Williamson, J. L.; Gadek, C. R.; Robinson, B. W.; Bautista, E.; Bauernfeind, S. M.; Baumann, M. J.; Gyllenhaal, E. F.; Marra, P. P.; Ricote, N.; Singh, N. D.; Valqui, T.; Witt, C. C.
10.1101/2024.07.03.601580 — zoology — Posted on 2024-09-23
1520 Characterising tandem repeat complexities across long-read sequencing platforms with TREAT and otter
Tesi, N.; Salazar, A.; Zhang, Y.; van der Lee, S.; Hulsman, M.; Knoop, L.; Wijesekera, S.; Krizova, J.; Schneider, A.-F.; Pennings, M.; Sleegers, K.; Kamsteeg, E.-J.; Reinders, M.; Holstege, H.
10.1101/2024.03.15.585288 — bioinformatics — Posted on 2024-09-23
1521 Microsatellite Density Landscapes Illustrate Short Tandem Repeats Aggregation in The Complete Reference Human Genome
Xia, Y.; Li, D.; Chen, T.; Pan, S.; Huang, H.; Zhang, W.; Liang, Y.; Fu, Y.; Peng, Z.; Zhang, H.; Zhang, L.; Peng, S.; Shi, R.; He, X.; Zhou, S.; Jiao, W.; Zhao, X.; Wu, X.; Zhou, L.; Zhou, J.; Ouyang, Q.; Tian, Y.; Jiang, X.; Zhou, Y.; Tang, S.; Shen, J.; Ohshima, K.; Tan, Z.
10.1101/2022.04.16.487617 — bioinformatics — Posted on 2024-09-23
1522 Hidden GPCR structural transitions addressed by multiple walker supervised molecular dynamics (mwSuMD)
Deganutti, G.; Pipito, L.; Rujan, R. M.; Weizmann, T.; Griffin, P.; Ciancetta, A.; Moro, S.; Reynolds, C. A.
10.1101/2022.10.26.513870 — bioinformatics — Posted on 2024-09-23
1525 PhyloFunc: Phylogeny-informed Functional Distance as a New Ecological Metric for Metaproteomic Data Analysis
Wang, L.; Simopoulos, C. M. A.; Serrana, J. M.; Ning, Z.; Li, Y.; Sun, B.; Yuan, J.; Figeys, D.; Li, L.
10.1101/2024.05.28.596184 — bioinformatics — Posted on 2024-09-23
1528 scooby: Modeling multi-modal genomic profiles from DNA sequence at single-cell resolution
Hingerl, J. C.; Martens, L. D.; Karollus, A.; Manz, T.; Buenrostro, J. D.; Theis, F. J.; Gagneur, J.
10.1101/2024.09.19.613754 — genomics — Posted on 2024-09-23
1529 Resolving out of Africa event for Papua New Guinean population using neural network
Mondal, M.; Andre, M.; Pathak, A. K.; Brucato, N.; Ricaut, F.-X.; Metspalu, M.; Eriksson, A.
10.1101/2024.09.19.613861 — genetics — Posted on 2024-09-23
1531 On the discovered Cancer Driving Nucleotides (CDNs)-Distributions across genes, cancer types and patients
Zhang, L.; Deng, T.; Liufu, Z.; Chen, X.; Wu, S.; Liu, X.; Shi, C.; Chen, B.; Hu, Z.; Cai, Q.; Liu, C.; Li, M.; Tracy, M. E.; Lu, X.; Wu, C.-I.; Wen, H.-J.
10.1101/2024.05.29.596367 — evolutionary biology — Posted on 2024-09-23
1532 Effects of copepod chemical cues on intra- and extracellular toxins in two species of Dinophysis
Pourdanandeh, M.; Sechet, V.; Carpentier, L.; Reveillon, D.; Herve, F.; Hubert, C.; Hess, P.; Selander, E.
10.1101/2024.07.17.603891 — ecology — Posted on 2024-09-23
1536 Expert Navigators Deploy Rational Complexity-Based Decision Prioritization for Large-Scale Real-World Planning
Fernandez Velasco, P.; Griesbauer, E.-M.; Brunec, I.; Morley, J.; Manley, E.; McNamee, D.; Spiers, H.
10.1101/2024.03.25.586612 — neuroscience — Posted on 2024-09-23
1539 A neuronal least-action principle for real-time learning in cortical circuits
Senn, W.; Dold, D.; Kungl, A.; Ellenberger, B.; Jordan, J.; Bengio, Y.; Sacramento, J.; Petrovici, M. A.
10.1101/2023.03.25.534198 — neuroscience — Posted on 2024-09-23
1541 Modulation of RNA processing genes during sleep-dependent memory
Li, Y.; Chouhan, N. S.; Zhang, S. L.; Moore, R. S.; Noya, S. B.; Shon, J.; Yue, Z.; Sehgal, A.
10.1101/2023.05.31.543136 — neuroscience — Posted on 2024-09-23
1542 Myofibre-specific knockout of TGF-β type I receptors triggers muscle hypertrophy and promotes contraction and oxidative metabolism
Shi, A.; Hillege, M. M. G.; Noort, W.; Offringa, C.; Wu, G.; Forouzanfar, T.; Hoogaars, W. M. H.; Wüst, R. C. I.; Jaspers, R. T.
10.1101/2023.08.30.555466 — physiology — Posted on 2024-09-23
1543 Impact of genomic background and developmental state on signaling pathways and response to therapy in Glioblastoma patient-derived cells
Berezovsky, A. D.; Nuga, O.; Datta, I.; Bergman, K.; Sabedot, T.; Gurdziel, K.; Irtenkauf, S.; Hasselbach, L.; Meng, Y.; Mueller, C.; Petricoin, E.; Brown, S.; Purandare, N.; Aras, S.; Mikkelsen, T.; Poisson, L.; Noushmehr, H.; Ruden, D. M.; deCarvalho, A.
10.1101/2024.03.14.585115 — cancer biology — Posted on 2024-09-23
1549 Evaluating Physiological Indicators in Detecting Deception and Truthfulness using theComparison Question Test (CQT)
Rashid, A. M. S.; Carmichael, B.; Su, C.; Shi, K.; Lim, K.; Kumar, P. S.; Wan, N. J.; Govil, E.; Yap, D.
10.1101/2024.09.01.609623 — bioengineering — Posted on 2024-09-23
1556 Cholinergic Neuronal Activity Promotes Diffuse Midline Glioma Growth through Muscarinic Signaling
Monje, M.; Deisseroth, K.; Drinnenberg, A.; Drexler, R.; Gavish, A.; Yalcin, B.; Shamardani, K.; Rogers, A.; Mancusi, R.; Taylor, K. R.; Kim, Y. S.; Woo, P. J.; Ravel, A.; Tatlock, E.; Ayala-Sarmiento, A. E.; Rincon Fernandez Pacheco, D.; Ramakrishnan, C.; Daigle, T. L.; Siverts, L.; Tasic, B.; Zeng, H.
10.1101/2024.09.21.614235 — neuroscience — Posted on 2024-09-23
1563 Widespread brain activity increases in frontal lobe seizures with impaired consciousness
Salardini, E.; Vaddiparti, A.; Kumar, A.; Martin, R. A.; Gebere, R. Z.; Arencibia, C. A.; Dhakar, M. B.; Grover, E. H.; Quraishi, I. H.; Sternberg, E. J.; George, I. C.; Sivaraju, A.; Bonito, J.; Zaveri, H. P.; Gober, L. M.; Ahmed, S.; Ghoshal, S.; Wu, K.; Farooque, P.; Hirsch, L. J.; Damisah, E.; Gerrard, J. L.; Spencer, D. D.; Yoo, J. Y.; Young, J. J.; Friedman, D.; Shum, J.; Blumenfeld, H.
10.1101/2024.09.20.614207 — neuroscience — Posted on 2024-09-23
1565 Traumatic Brain Injury Exacerbates Alcohol Consumption and Neuroinflammation with Decline in Cognition and Cholinergic Activity
Gangal, H.; Iannucci, J.; Huang, Y.; Chen, R.; Purvines, W.; Davis, T.; Rivera, A.; Johnson, G.; Xie, X.; Mukherjee, S.; Vierkant, V.; Mims, K.; O'Neill, K.; Wang, X.; Shapiro, L.; Wang, J.
10.1101/2024.09.21.614247 — neuroscience — Posted on 2024-09-23
1568 Congruent brain signatures specific to speech sounds in fronto-temporal cortex during language production and understanding.
Dmitrieva, X.; Anton, J.-L.; Runnqvist, E.; Fairs, A.; Ivanova, B.; Sein, J.; Nazarian, B.; Dufour, S.; Pulvermuller, F.; Strijkers, K.
10.1101/2024.09.22.614347 — neuroscience — Posted on 2024-09-23
1569 Olfactory and Trigeminal Routes of HSV-1 CNS Infection with Regional Microglial Heterogeneity
Niemeyer, C.; Merle, L.; Bubak, A. N.; Baxter, B. D.; Polese, A. G.; Colon-Reyes, K.; Vang, S.; Hassell, J. E.; Bruce, K. D.; Nagel, M. A.; Restrepo, D.
10.1101/2024.09.22.614340 — neuroscience — Posted on 2024-09-23
1574 TWINKLE: An open-source two-photon microscope for teaching and research
Schottdorf, M.; Rich, P. D.; Diamanti, E. M.; Lin, A.; Tafazoli, S.; Nieh, E. H.; Thiberge, S. Y.
10.1101/2024.09.23.612766 — neuroscience — Posted on 2024-09-23
1576 The Visual Experience Evaluation Tool: A Myopia Research Instrument for Quantifying Visual Experience
Sullivan, D.; Nicholls, A.; Thompson, S.; Schwarzmiller, C.; Hatoun, G.; Memarzanjany, F.; Gunderson, A.; Danielson, A.; Lowes, J.; Petersen, J.; Backes, S.; Rutherford, L.
10.1101/2024.09.20.614212 — neuroscience — Posted on 2024-09-23
1578 Tau P301S Transgenic Mice Develop Gait and Eye Movement Impairments That Mimic Progressive Supranuclear Palsy
Creed, R. B.; Harris, S. C.; Sridhar, S.; du Lac, S.; Zee, D. S.; Dunn, F. A.; Bouvier, G.; Nelson, A. B.
10.1101/2024.09.20.614197 — neuroscience — Posted on 2024-09-23
1581 PointTree: Automatic and accurate reconstruction of long-range axonal projections of single-neuron
Cai, L.; Fan, T.; Qu, X.; Zhang, Y.; Gou, X.; Ding, Q.; Feng, W.; Cao, T.; Lv, X.; Liu, X.; Huang, Q.; Quan, T.; Zeng, S.
10.1101/2024.09.23.614432 — neuroscience — Posted on 2024-09-23
1582 A one-step protocol to generate impermeable fluorescent HaloTag substrates for in situ live cell application and super-resolution imaging
Rossmann, K.; Sun, S.; Olesen, C. H.; Kowald, M.; Tapp, E.; Pabst, U.; Bieck, M.; Birke, R.; Shields, B. C.; Jeong, P.; Hong, J.; Tadross, M. R.; Levitz, J.; Lehmann, M.; Lipstein, N.; Broichhagen, J.
10.1101/2024.09.20.614087 — pharmacology and toxicology — Posted on 2024-09-23
1585 High-resolution awake mouse fMRI at 14 Tesla
Hike, D.; Liu, X.; Xie, Z.; Zhang, B.; Choi, S.; Zhou, X. A.; Liu, A.; Murstein, A.; Jiang, Y.; Devor, A.; Yu, X.
10.1101/2023.12.08.570803 — neuroscience — Posted on 2024-09-23
1586 TBX15 regulates a network of immune response genes in adipose tissue and alters fat mass and depot weight in heterozygous knockout mice
Zolkiewski, L.; Simon, M.; Harrison, J.; Vizor, L.; Ireson, E.; Moir, L.; Yon, M. A.; Beresford, L.; Rodrigues, A.; Hawkins, J.; Hill, S.; Bentley, L.; Cox, R. D.; Dumbell, R.
10.1101/2024.09.20.614167 — physiology — Posted on 2024-09-23
1589 The synergy between cannabidiol and probiotics curtails the glycemic indicators, enhances insulin production, and alleviates the symptoms of type 2 diabetes.
Naeini, S. E.; Bhandari, B.; Rogers, H. M.; Gouron, J.; Chagas, P. S.; Maciel, L. M.; Chagas, H. I. S.; Yu, J. C.; Seyyedi, M.; Salles, E. L.; Fields, M.; Baban, B.; Wang, L. P.
10.1101/2024.06.04.597375 — molecular biology — Posted on 2024-09-23
1590 Prophages are Infrequently Associated With Antibiotic Resistance in Pseudomonas aeruginosa Clinical Isolates
Chang, T. H.; Pourtois, J.; Haddock, N.; Furkuawa, D.; Kelly, K. E.; Amanatullah, D.; Burgener, E. B.; Milla, C.; Banaei, N.; Bollyky, P.
10.1101/2024.06.02.595912 — microbiology — Posted on 2024-09-23
1593 MRAP2 modifies signaling and oligomerization state of the melanocortin-4 receptor
Sohail, I.; Laurin, S.-A.; Kleinau, G.; Chunilal, V.; Morton, A.; Kagiali, Z. C. U.; Tello, J. A.; Lohse, M. J.; Scheerer, P.; Bouvier, M.; McCormick, P.; Annibale, P.; Biebermann, H.
10.1101/2024.04.09.588099 — pharmacology and toxicology — Posted on 2024-09-23
1600 The utility of environmental data from traditionalvarieties for climate-adaptive maize breeding
Li, F.; Gates, D. J.; Buckler, E. S.; Hufford, M. B.; Janzen, G. M.; Rellan-Alvarez, R.; Rodriguez-Zapata, F.; Navarro, J. A. R.; Sawers, R. J.; Snodgrass, S. J.; Sonder, K.; Willcox, M. C.; Hearne, S.; Ross-Ibarra, J.; Runcie, D. E.
10.1101/2024.09.19.613351 — evolutionary biology — Posted on 2024-09-23
1601 Mean daily temperatures can predict the thermal limits of malaria transmission better than rate summation
Shocket, M. S.; Bernhardt, J. R.; Miazgowicz, K. L.; Orakzai, A.; Savage, V. M.; Hall, R. J.; Ryan, S. J.; Murdock, C. C.
10.1101/2024.09.20.614098 — ecology — Posted on 2024-09-23
1602 Endosymbionts impact ladybird predation rates of aphids in a temperature-dependent manner
Thomsen, K. B.; Ross, P. A.; Gill, A.; Yang, Q.; Stelmach, M.; Callahan, A.; Oersted, M.; Hoffmann, A. A.; Kristensen, T. N.
10.1101/2024.09.20.614137 — ecology — Posted on 2024-09-23
1603 The exit of naïve pluripotency contains a lipid metabolism-induced checkpoint for genome integrity.
de Souza, R. A.; Barneda, D.; Karimlou, D.; Bovee, N. G. P.; Zheng, Y.; Kahlman, E. J. E. M.; Lopes Novo, C.; Ellis, J. K.; Leeke, B. J.; Prakash Bangalore, M.; Liu, Z.; Sousa, B. C.; Lopez-Clavijo, A. F.; Jansen, J. H.; Barahona, M.; Percharde, M.; Keun, H. C.; Christian, M.; Marks, H.; Azuara, V.
10.1101/2024.09.22.613751 — developmental biology — Posted on 2024-09-23
1607 Lysosomal LRRC8 complex regulates lysosomal pH, morphology and systemic glucose metabolism
Kumar, A.; Zhao, Y.; Xie, L.; Chadda, R.; Abraham, N.; Hong, J.; Feng, E.; Tranter, J. D.; Rawnsley, D.; Liu, H.; Henry, K. M.; Meyer, G.; Hu, M.; Xu, H.; Hinton, A.; Grueter, C. E.; Abel, E. D.; Norris, A. W.; Diwan, A.; Sah, R.
10.1101/2024.09.22.614256 — cell biology — Posted on 2024-09-23
1608 FcγR- and CD9-dependent synapse engulfing microglia in the thalamus drives cognitive impairment following cortical brain injury
Matoba, K.; Kochi, T.; Mreyoud, Y. R.; Badrani, J. H.; Patel, H.; Tsujioka, H.; Yamashita, T.; Crossman, D. K.; Niwa, M.; Kano, S.
10.1101/2024.09.19.609743 — immunology — Posted on 2024-09-23
1609 A novel method for characterizing cell-cell interactions at single-cell resolution reveals unique signatures in blood T cell-monocyte complexes during infection
Kang, N.; Chawla, A.; Hillman, H.; Tippalagama, R.; Kim, C.; Mikulski, Z.; Seumois, G.; Vijayanand, P.; Scriba, T. J.; De Silva, A. D.; Balmaseda, A.; Harris, E.; Weiskopf, D.; Sette, A.; Lindestam Arlehman, C.; Peters, B.; Burel, J. G.
10.1101/2024.09.20.612103 — immunology — Posted on 2024-09-23
1611 Expanding Automated Multiconformer Ligand Modeling to Macrocycles and Fragments
Flowers, J.; Echols, N.; Correy, G.; Jaishankar, P.; Togo, T.; Renslo, A. R.; van den Bedem, H.; Fraser, J. S.; Wankowicz, S. A.
10.1101/2024.09.20.613996 — biophysics — Posted on 2024-09-23
1612 Unraveling the GM1 specificity of Galectin-1 binding to lipid membranes
Scollo, F.; Kulig, W.; Nicita, G.; Ludwig, A.-K.; Ricardo, J. C.; Zito, V.; Kapusta, P.; Vattulainen, I.; Cebecauer, M.; Gabius, H.-J.; Kaltner, H.; Maccarrone, G.; Hof, M.
10.1101/2024.09.20.614102 — biophysics — Posted on 2024-09-23
1618 Comparative pan-genomics reveals divergent adaptations in clinically-relevant members of the Fusarium solani species complex
Brassington, P. J.; Fabre, M. L.; Zimmermann, A.; Perrier, M.; Martin, R.; Kurzai, O.; Barber, A. E.
10.1101/2024.09.23.614396 — genomics — Posted on 2024-09-23
1624 Transient Notch Activation Converts Pluripotent Stem Cell-Derived Cardiomyocytes towards a Purkinje Fiber Fate
Gonzalez, D. M.; Dariolli, R.; Moyett, J.; Song, S.; Shewale, B.; Bliley, J. M.; Ma'ayan, A.; Rentschler, S.; Feinberg, A. W.; Sobie, E.; Dubois, N.
10.1101/2024.09.22.614353 — developmental biology — Posted on 2024-09-23
1625 Unsaturated lipids as key control points for caveola formation and disassembly
Wu, Y.; Lim, Y.-W.; McMahon, K.-A.; Martel, N.; Rae, J.; Lo, H.; Gao, Y.; Tillu, V.; Larsson, E.; Lundmark, R.; Levic, D. S.; Bagnat, M.; Lim, J.; Fairlie, D. P.; Pol, A.; Collins, B.; Ariotti, N.; Hall, T. E.; Parton, R. G.
10.1101/2024.09.22.614381 — cell biology — Posted on 2024-09-23
1626 Profiling the endothelial translatome in vivo using 'AngioTag' zebrafish
Miller, M. F.; Greenspan, L. J.; Gildea, D. E.; Monzo, K.; Margolin, G.; Pham, V. N.; Ameyaw, K.; Price, L.; Aloi, N.; Stratman, A. N.; Davis, A. E.; Cisneros, I.; Mertus, C.; Dale, R. K.; Baxevanis, A. D.; Weinstein, B. M.
10.1101/815696 — developmental biology — Posted on 2024-09-23
1627 Sex-specific effects of early life unpredictability on hippocampal and amygdala responses to novelty in adolescents
Davis, E. P.; Leonard, B.; Jirsaraie, R.; Keator, D.; Small, S.; Sandman, C. A.; Risbrough, V.; Stern, H. S.; Glynn, L.; Yassa, M. A.; Baram, T. Z.; Rasmussen, J.
10.1101/2024.09.20.614130 — neuroscience — Posted on 2024-09-23
1628 Chromosome-level Genome Assembly and Annotation of Petunia hybrida
Saei, A.; Hunter, D.; Hilario, E.; David, C.; Ireland, H.; Esfandiari, A.; King, I.; Grierson, E.; Wang, L.; Boase, M.; Kramer, M.; Shakya, S.; Bowman, M.; Barbey, C. R.; Chagne, D.
10.1101/2024.09.19.611905 — genomics — Posted on 2024-09-23
1629 BEDMS: A metadata standardizer for genomic regionattributes
Tambe, S.; Khoroshevskyi, O.; Park, S.-H.; LeRoy, N. J.; Campbell, D. R.; Zheng, G.; Zhang, A.; Sheffield, N. C.
10.1101/2024.09.18.613791 — genomics — Posted on 2024-09-23
1630 LINE1 promotes nuclear compartmentalization to repress the 8-cell state in embryonic stem cells
Zhang, J.; Ataei, L.; Wu, L.; Mittal, K.; Huynh, L.; Sarajideen, S.; Mazid, M. A.; Cook, D. P.; Trcka, D.; Tse, K.; Wrana, J. L.; Hoffman, M. M.; Esteban, M. A.; Ramalho-Santos, M.
10.1101/2024.09.22.614332 — developmental biology — Posted on 2024-09-23
1631 Defining the Vascular Niche of Human Adipose Tissue Across Metabolic Conditions
AlZaim, I.; Hassan, M. N.; Mannino, L.; Dragicevic, K.; Sjogaard, M. B.; Festa, J.; Dokshokova, L.; Hansen, B.; Christensen, J. N.; Farup, J.; Lin, L.; Soraggi, S.; Thomsen, H. H.; Schipper, R.; Rasmussen, R. K.; von Heesen, M.; Conradi, L.-C.; Hagberg, C. E.; Heeren, J.; Etzerodt, A.; Emont, M. P.; Rosen, E.; Massier, L.; Ryden, M.; Mejhert, N.; Blueher, M.; Khodosevich, K.; Sheikh, B.; Jessen, N.; de Rooij, L. P. M. H.; Kalucka, J.
10.1101/2024.09.22.610444 — cell biology — Posted on 2024-09-23
1632 PEBP1 amplifies mitochondrial dysfunction induced integrated stress response
Cheng, L.; Meliala, I.; Kong, Y.; Chen, J.; Proud, C. G.; Björklund, M.
10.1101/2024.09.20.614039 — cell biology — Posted on 2024-09-23
1633 The response of multi-disease and insect-resistant tomato lines to the accumulation of TYLCV, a whitefly-transmitted virus
Prabhakar, S. S.; Hsu, Y.-c.; Yen, J.; Chou, H.-y.; Lin, M.-y.; Priya, M. S.; Ramasamy, S.; Eybishitz, A.
10.1101/2024.09.21.614278 — plant biology — Posted on 2024-09-23
1634 Field-crop transcriptome models are enhanced by measurements in systematically controlled environments
Hashida, Y.; Kyogoku, D.; Tanaka, S. E.; Mori, N.; Tanabata, T.; Watanabe, H.; Nagano, A. J.
10.1101/2024.09.21.614268 — plant biology — Posted on 2024-09-23
1635 Medicago truncatula CORYNE regulates inflorescence meristem branching, nutrient signaling, and arbuscular mycorrhizal symbiosis
Orosz, J.; Lin, E. X.; Lindsay, P. L.; Kappes, M.; Bashyal, S.; Everett, H.; Gautam, C. K.; Jackson, D.; Mueller, L. M.
10.1101/2024.09.20.614181 — plant biology — Posted on 2024-09-23
1636 A repeatedly evolved mutation in Cryptochrome-1 of subterranean animals alters behavioral and molecular circadian rhythms
Swaminathan, A.; Kenzior, A.; McCoin, C.; Price, A.; Weaver, K.; Hintermann, A.; Morris, N.; Keene, A. C.; Rohner, N.
10.1101/2024.09.19.613894 — evolutionary biology — Posted on 2024-09-23
1637 The evolution and developmental dynamics of histone-based chromatin regulation in Annelida
Martin-Zamora, F. M.; Cole, J.; Donnellan, R. D.; Guynes, K.; Carrillo-Baltodano, A. M.; Dickman, M. J.; Hurd, P. J.; Martin-Duran, J. M.
10.1101/2024.09.20.614060 — evolutionary biology — Posted on 2024-09-23
1640 A novel OsIAA3-OsARF16-OsBUL1 module regulates grain size in rice
Xian, F.; Liu, S.; Huang, J.; Xie, B.; Zhu, L.; Zhang, Q.; Lv, C.; Xu, Y.; Zhang, X.; Hu, J.
10.1101/2024.09.19.613952 — genetics — Posted on 2024-09-22
1641 BRCA2 C-terminal clamp restructures RAD51 dimers to bind B-DNA for replication fork stability
Longo, M. A.; Ahmed, S. M.; Chen, Y.; Tsai, C.-L.; Wang, X.; Perera, R.; Arvai, A.; Lee, M.; Kong, L. R.; Engl, W.; Shyuan, W.; Zhao, Z. W.; Venkitaraman, A. R.; Tainer, J. A.; Schlacher, K.
10.1101/2024.09.21.614229 — molecular biology — Posted on 2024-09-22
1645 Airway applied IVT mRNA vaccine needs specific sequence design and high standard purification that removes devastating dsRNA contaminant
Zhang, J.; Li, C.; Liu, Y.; Liao, R.; He, D.; Xu, L.; Chen, T.; Xiao, Q.; Luo, M.; Chen, Y.; Li, Y.; Zhu, H.; Rosenecker, J.; Ding, X.; Pei, S.; Guan, S.
10.1101/2024.09.22.614306 — synthetic biology — Posted on 2024-09-22
1647 Identification of the orphan GPR25 as a receptor of the chemokine CXCL17
Hu, W.-F.; Yu, J.; Wang, J.-J.; Sun, R.-J.; Zheng, Y.-S.; Zhang, T.; Liu, Y.-L.; Xu, Z.-G.; Guo, Z.-Y.
10.1101/2024.09.21.614233 — biochemistry — Posted on 2024-09-22
1649 scooby: Modeling multi-modal genomic profiles from DNA sequence at single-cell resolution
Gagneur, J.; Hingerl, J. C.; Martens, L. D.; Manz, T.; Theis, F. J.; Buenrostro, J. D.; Karollus, A.
10.1101/2024.09.19.613754 — genomics — Posted on 2024-09-22
1650 Evaluating the Radiation Sensitivity Index and 12-chemokine gene expression signature for clinical use in a CLIA laboratory
Berglund, A.; Puskas, J.; Yoder, S.; Smith, A. T.; Marchion, D. C.; Qin, D.; Mule, J.; Torres-Roca, J. F.; Eschrich, S. A.
10.1101/2024.09.19.613957 — genomics — Posted on 2024-09-22
1654 Anti-tubercular potential and pH-driven mode of action of salicylic acid derivatives
Laudouze, J.; Francis, T.; Forest, E.; Mies, F.; Bolla, J.-M.; Crauste, C.; Canaan, S.; Shlyonsky, V.; Santucci, P.; Cavalier, J.-F.
10.1101/2024.09.22.614344 — microbiology — Posted on 2024-09-22
1655 Early life milk diets shape infant gut microbiota: evidence of microbial plasticity in response to breast and formula milk.
Lawson, M. A. E.; Dalby, M.; Caim, S.; Richardson, L.; Koulman, A.; Kiu, R.; Le Gall, G.; Hall, L. J.
10.1101/2024.09.22.614312 — microbiology — Posted on 2024-09-22
1661 Closing the gaps: testing the efficacy of carbapenem and cephalosporins in treating late-stage anthrax
Sittner, A.; Bar-David, E.; Glinert, I.; Ben-Smueal, A.; Schlomovitz, J.; Levy, H.; Weiss, S.
10.1101/2024.09.21.614292 — microbiology — Posted on 2024-09-22
1665 Tailoring a CRISPR/Cas-based Epigenome Editor for Programmable Chromatin Acylation and Decreased Cytotoxicity
Goell, J. H.; Li, J.; Mahata, B.; Ma, A. J.; Kim, S.; Shah, S.; Shah, S.; Contreras, M.; Misra, S.; Reed, D.; Bedford, G. C.; Escobar, M.; Hilton, I. B.
10.1101/2024.09.22.611000 — synthetic biology — Posted on 2024-09-22
1666 Structural and functional analysis of cancer-associated missense variants in the retinoblastoma protein (Rb) pocket domain
Castro, A.; Ruiz-Rivera, A.; Moorman, C. C.; Wolf-Saxon, E. R.; Mims, H. N.; Vasquez-Meza, V. I.; Rangel, M. A.; Loera, M. M.; Bond, I.; Buchanan, S. B.; Villarreal, E.; Tripathi, S.; Rubin, S. M.; Burke, J. R.
10.1101/2024.09.22.614354 — biochemistry — Posted on 2024-09-22
1669 A Novel Technique for Fluorescence Lifetime Tomography
Nizam, N. I.; Pandey, V.; Erbas, I.; Smith, J. T.; Intes, X.
10.1101/2024.09.19.613888 — bioengineering — Posted on 2024-09-22
1670 Insecticide resistance in Myzus persicae collected from sweet pepper
Beekman, M. M.; Ruan, X.; Dicke, M.; Zwaan, B. J.; Pannebakker, B. A.; Verhulst, E. C.
10.1101/2024.09.19.613823 — genetics — Posted on 2024-09-22
1672 Adaptive immunity shapes innate and epithelial cell landscapes by silencing tonic IFN-gamma in innate lymphoid cells during homeostasis.
Mejri, O.; Ma, L.; Aoudi, A.; Labiad, O.; Mondot, S.; IGALOUZENE, R.; Codan, C.; Hernandez-Vargas, H.; Rousseaux, N.; Lapaque, N.; Paul, S.; Walzer, T.; Marie, J. C.; Soudja, S.
10.1101/2024.09.19.613869 — immunology — Posted on 2024-09-22
1673 A lymphoid tissue chemokine checkpoint prevents loss of CD8+ T cell functionality
Altenburger, L. M.; Claudino Carvoeiro, D.; Dehio, P.; Zhou, J.; Laura, C.; Katoch, M.; Krueger, C.; Barreto de Albuquerque, J.; Pfenninger, P.; Martinez Magdaleno, J.; Abe, J.; Mehling, M.; Dengjel, J.; Iannacone, M.; Hashemi Gheinani, A.; Stein, J. V.
10.1101/2024.09.19.613830 — immunology — Posted on 2024-09-22
1674 A helper NLR targets organellar membranes to trigger immunity
Ibrahim, T.; Yuen, E. L. H.; Wang, H.-Y.; King, F. J.; Toghani, A.; Kourelis, J.; Vuolo, C.; Adamkova, V.; Castel, B.; Jones, J. D.; Wu, C.-H.; Kamoun, S.; Bozkurt, T. O.
10.1101/2024.09.19.613839 — plant biology — Posted on 2024-09-22
1675 Ablation of hematopoietic stem cell derived adipocytes reduces tumor burden in syngeneic mouse models of high-grade serous carcinoma
Woodruff, E. R.; Bailey, C. A.; To, F.; Manda, V.; Maltzahn, J. K.; Sullivan, T. M.; Boorgula, M. P.; Recouvreux, M. S.; Vianzon, R.; Conrad, B.; Gavin, K. M.; Jordan, K. R.; Klemm, D. J.; Orsulic, S.; Bitler, B. G.; Watson, Z. L.
10.1101/2024.09.19.613924 — cancer biology — Posted on 2024-09-22
1676 Selective loss of Y chromosomes in lung adenocarcinoma modulates the tumor immune environment through cancer/testis antigens
Fischer, J.; Shutta, K. H.; Chen, C.; Fanfani, V.; Saha, E.; Mandros, P.; Ben Guebila, M.; Xiu, J.; Nieva, J.; Liu, S.; Uprety, D.; Spetzler, D.; Lopes-Ramos, C.; DeMeo, D. L.; Quackenbush, J.
10.1101/2024.09.19.613876 — cancer biology — Posted on 2024-09-22
1681 Multi-generational biotic stress increases the rate of spontaneous epimutations in a ROS1-dependent manner
Zhang, Z.; Parker, A. H.; Symeonidi, A.; Wilkinson, S. W.; Stassen, J. H. M.; Smith, L. M.; Ton, J.; Johannes, F.
10.1101/2024.09.19.613880 — evolutionary biology — Posted on 2024-09-22
1682 Temperature-dependent predation predicts a more reptilian future
Grady, J. M.; Amme, J. L.; Bhaskaran-Nair, K.; Sinha, V.; Brunwasser, S. J.; Record, S.; Dell, A. I.; Hengen, K. B.
10.1101/2024.09.19.613816 — ecology — Posted on 2024-09-22
1683 Drivers of host-pathogen community assemblies in European forests and urban green spaces
Sluydts, V.; Bouilloud, M.; Galan, M.; Alburkat, H.; Bordes, A.; Bourret, V.; Colombo, V.; DeBruyn, L.; Dutra, L.; Eccard, J.; Firozpoor, J.; Gallet, R.; Grzybek, M.; Henttonen, H.; Jacob, J.; McManus, A.; Sironen, T.; Stuart, P.; Tatard, C.; Roche, B.; Leirs, H.; Charbonnel, N.
10.1101/2024.09.19.613856 — ecology — Posted on 2024-09-22
1684 Rapid parallel adaptation in distinct invasions of Ambrosia artemisiifolia is driven by large-effect structural variants
Battlay, P.; Craig, S.; Putra, A. R.; Monro, K.; De Silva, N. P.; Wilson, J.; Bieker, V. C.; Kabir, S.; Shamaya, N.; van Boheemen, L.; Rieseberg, L. H.; Stinchcombe, J. R.; Fournier-Level, A.; Martin, M. D.; Hodgins, K. R.
10.1101/2024.09.18.613801 — genomics — Posted on 2024-09-22
1687 Development of a protein synthesis network at the sarco/endoplasmic reticulum in adult cardiac myocytes
Sandmann, C.; Sramek, V.; Brandenburg, S.; Uhlenkamp, D.; Renz, M.; Meyer, B.; Sandmann, C.; Herzog, N.; Gross, J.; Katus, H. A.; Lehnart, S. E.; Voelkers, M.; Doroudgar, S.
10.1101/2024.09.20.614189 — cell biology — Posted on 2024-09-22
1688 Divergent Plasmodium protein kinases drive MTOC, kinetochore and axoneme organisation in male gametogenesis
Yanase, R.; Zeeshan, M.; Ferguson, D. J.; Markus, R.; Brady, D.; Bottrill, A. R.; Holder, A. A.; Guttery, D. S.; Tewari, R.
10.1101/2024.09.22.613647 — microbiology — Posted on 2024-09-22
1690 Loss of PARP7 increases type I interferon signalling and prevents pancreatic tumour growth by enhancing immune cell infiltration
Kannen, V.; Rasmussen, M.; Das, S.; Giuliana, P.; Izzati, F. N.; Choksi, H.; Erlingsson, L. A. M.; Olafsen, N. E.; Cappello, P.; Teino, I.; Maimets, T.; Jaudzems, K.; Gulbinas, A.; Dambrauskas, Z.; Edgar, L. J.; Grant, D. M.; Matthews, J.
10.1101/2024.09.18.613621 — cancer biology — Posted on 2024-09-22
1692 Family-Wide Photoproximity Profiling of Integrin Protein Social Networks in Cancer
Carlos, A. J.; Yang, D.; Thomas, D. M.; Huang, S.; Harter, K. I.; Moellering, R. E.
10.1101/2024.09.18.613588 — cancer biology — Posted on 2024-09-22
1693 Protrusion force and cell-cell adhesion play a critical role in collective tumor cluster migration
Wang, H.; Ardila, C.; Jindal, A.; Aggarwal, V.; Wang, W.; Vande Geest, J.; Jiang, Y.; Xing, J.; Sant, S.
10.1101/2024.09.18.613706 — cancer biology — Posted on 2024-09-22
1694 Examination of INPP5A in uveal melanoma uncovers novel calcium transients
Onken, M. D.; Kaltenbronn, K. M.; Makepeace, C. M.; Piggott, K. D.; Blumer, K. J.
10.1101/2024.09.18.613756 — cancer biology — Posted on 2024-09-22
1696 Chromosome-level assemblies of Amaranthus palmeri, Amaranthus retroflexus, and Amaranthus hybridus allow for genomic comparisons and identification of a sex-determining region
Raiyemo, D. A.; Montgomery, J. S.; Cutti, L.; Abdollahi, F.; Llaca, V.; Fengler, K.; Lopez, A. J.; Morran, S.; Saski, C. A.; Nelson, D. R.; Patterson, E.; Gaines, T. A.; Tranel, P. J.
10.1101/2024.09.18.613719 — genomics — Posted on 2024-09-22
1700 Complex genomic ancestry in southern regions and drivers of continental-level genetic diversity in the wolves of Asia
Hennelly, L.; Parreira, B. R.; Nobel, A.; Scharff-Olsen, C.; Kemahi Aytekin, M. C.; Sekercioglu, C.; Kosintsev, P.; Paule, L.; Hulva, P.; Stenoien, H. K.; Habib, B.; Fatima, H.; Sarwar, G.; El-Haddad, S. P.; Hailer, F.; Sun, X.; Martins, N. F.; Gilbert, M. T. P.; Sinding, M.-H. S.; Sacks, B. N.; Gopalakrishnan, S.
10.1101/2024.09.18.613796 — evolutionary biology — Posted on 2024-09-22
1704 Cohesin-mediated chromatin remodeling controls the differentiation and function of conventional dendritic cells
Adams, N. M.; Galitsyna, A.; Tiniakou, I.; Esteva, E.; Lau, C. M.; Reyes, J.; Abdennur, N.; Shkolikov, A.; Yap, G. S.; Khodadadi-Jamayran, A.; Mirny, L.; Reizis, B.
10.1101/2024.09.18.613709 — immunology — Posted on 2024-09-22
1705 Overcoming immune evasion from post-translational modification of a mutant KRAS epitope to achieve TCR-engineered T cell-mediated antitumor activity
Lee, J. W.; Chen, E. Y.; Hu, T.; Perret, R.; Chaffee, M. E.; Martinov, T.; Mureli, S.; McCurdy, C. L.; Jones, L. A.; Gafken, P. R.; Chanana, P.; Su, Y.; Chapuis, A. G.; Bradley, P.; Schmitt, T. M.; Greenberg, P. D.
10.1101/2024.09.18.612965 — immunology — Posted on 2024-09-22
1706 BCR ligation selectively inhibits IgE class switch recombination
Wade-Vallance, A. K.; Yang, Z.; Libang, J. B.; Krishnapura, A. R.; Jung, J. B.; Matcham, E. W.; Robinson, M. J.; Allen, C. D. C.
10.1101/2024.09.18.613749 — immunology — Posted on 2024-09-22
1707 Peptide-MHC-targeted retroviruses enable in vivo expansion and gene delivery to tumor-specific T cells
Xu, E. J.; Smith, B. E.; Conce Alberto, W. D.; Walsh, M. J.; Lim, B.; Hoffman, M. T.; Qiang, L.; Dong, J.; Garmilla, A.; Zhao, Q. H.; Perez, C. R.; Gaglione, S. A.; Dobson, C. S.; Dougan, M.; Dougan, S. K.; Birnbaum, M. E.
10.1101/2024.09.18.613594 — immunology — Posted on 2024-09-22
1710 Data-Independent Acquisition Mass Spectrometry as a Tool for Metaproteomics: Interlaboratory Comparison Using a Model Microbiome
Rajczewski, A. T.; Blakeley-Ruiz, J.; Meyer, A.; Vintila, S.; Mcilvin, M. R.; Van Den Bossche, T.; Searle, B. C.; Griffin, T.; Saito, M.; Kleiner, M.; Jagtap, P.
10.1101/2024.09.18.613707 — systems biology — Posted on 2024-09-22
1713 Increased cGMP improves microvascular exercise training adaptations independent of endothelial nitric oxide synthase
Winn, N. C.; Cappel, D. A.; Pollock, E. D.; Lantier, L.; Riveros, J. K.; Debrow, P.; Bracy, D. P.; Beckman, J. A.; Wasserman, D. H.
10.1101/2024.09.18.612717 — physiology — Posted on 2024-09-22
1715 Pharmacological SOS1 inhibitor BI-3406 demonstrates in vivo anti-tumor activity comparable to SOS1 genetic ablation in KRAS mutant tumors
BALTANAS, F. C.; Kramer-Drauberg, M.; Garcia-Navas, R.; Patrucco, E.; Petrini, E.; Arnhof, H.; Olarte-San Juan, A.; Rodriguez-Ramos, P.; Borrajo, J.; Calzada, N.; Castellano, E.; Mair, B.; Kostyrko, K.; Hofmann, M. H.; Ambrogio, C.; Santos, E.
10.1101/2024.09.18.613686 — cancer biology — Posted on 2024-09-22
1716 Loss of SMARCB1 evokes targetable epigenetic vulnerabilities in Epithelioid Sarcoma
Jin, J. X.; Fuchslocher, F.; Carreno-Gonzalez, M. J.; Zahnow, F.; Ceranski, A. K.; Will, R.; Helm, D.; Bestvater, F.; Banito, A.; Imle, R.; Ohmura, S.; Cidre-Aranaz, F.; Gruenewald, T. G. P.
10.1101/2024.09.18.613695 — cancer biology — Posted on 2024-09-22
1717 Gli2 Overexpression Alters the Differentiation Status of Dedifferentiated Liposarcoma Cells and Results in an Immunosuppressive Myeloid Phenotype in Orthotopic Tumors
Bennett, N. E.; Beadle, E. P.; Parker, D. V.; Coe, E. J.; Cottam, M. A.; Baum, J. E.; Miller, J. S.; Serrenho, J. A.; Rhoades, J. A.
10.1101/2024.09.18.613793 — cancer biology — Posted on 2024-09-22
1719 Halogenated cholesterol alters the phase behavior of ternary lipid membranes
Mehta, D.; Crumley, E. K.; Lou, J.; Best, M. D.; Waxham, N.; Heberle, F. A.
10.1101/2024.09.18.613775 — biophysics — Posted on 2024-09-22
1721 The Unified Phenotype Ontology (uPheno): A framework for cross-species integrative phenomics
Matentzoglu, N.; Bello, S. M.; Stefancsik, R.; Alghamdi, S. M.; Anagnostopoulos, A. V.; Balhoff, J. P.; Balk, M. A.; Bradford, Y. M.; Bridges, Y.; Callahan, T. J.; Caufield, H.; Cuzick, A.; Carmody, L. C.; Caron, A. R.; de Souza, V.; Engel, S. R.; Fey, P.; Fisher, M.; Gehrke, S.; Grove, C.; Hansen, P.; Harris, N. L.; Harris, M. A.; Harris, L.; Ibrahim, A.; Jacobsen, J. O. B.; Köhler, S.; McMurry, J. A.; Munoz-Fuentes, V.; Munoz-Torres, M. C.; Parkinson, H.; Pendlington, Z. M.; Pilgrim, C.; Robb, S. M. C.; Robinson, P. N.; Seager, J.; Segerdell, E.; Smedley, D.; Sollis, E.; Toro, S.; Vasilevsk
10.1101/2024.09.18.613276 — bioinformatics — Posted on 2024-09-22
1722 Development of a small-molecule epigenetic regenerative therapy. Subcutaneous administration of alginate formulations with high loads of zebularine and retinoic acid promotes tissue growth, vascularization and innervation and induces extensive epigenetic repatterning
Slonimska, P.; Baczynski-Keller, J.; Platek, R.; Deptula, M.; Dzierzynska, M.; Sawicka, J.; Krol, O.; Sosnowski, P.; Koczkowska, M.; Kostecka, A.; Crossman, D. K.; Crowley, M. R.; Sass, P.; Smolenski, R. T.; Skowron, P. M.; Piotrowski, A.; Pikula, M.; Rodziewicz-Motowidlo, S.; Sachadyn, P.
10.1101/2024.09.18.613177 — bioengineering — Posted on 2024-09-22
1723 Role of Forkhead box F1 in the Pathobiology of Pulmonary Arterial Hypertension
Gomez-Arroyo, J.; Houweling, A. C.; Bogaard, H. J.; Aman, J.; Kitzmiller, J. A.; Porollo, A.; Dooijes, D.; Meijboom, L. J.; Hale, P.; Pauciulo, M. W.; Hong, J.; Zhu, N.; Welch, C.; Shen, Y.; Zacharias, W. J.; McCormack, F. X.; Aldred, M. A.; Weirauch, M. T.; Graf, S. T.; Rhodes, C. J.; Chung, W. K.; Whitsett, J. A.; Martin, L. J.; Kalinichenko, V. K.; Nichols, W. A.
10.1101/2024.09.18.611448 — genomics — Posted on 2024-09-22
1724 Development and extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair for somatic benchmarks
McDaniel, J. H.; Patel, V.; Olson, N. D.; He, H.-J.; He, Z.; Schmitt, A.; Sikkink, K.; Sedlazeck, F.; Doddapaneni, H.; Jhangiani, S. N.; Muzny, D. M.; Gingras, M.-C.; Mehta, H.; Paulin, L. F.; Hastie, A. R.; Yu, H.-C.; Weigman, V.; Rojas, A.; Kennedy, K.; Remington, J.; Gonzalez, I.; Sudkamp, M.; Wiseman, K.; Lajoie, B.; Levy, S.; Jain, M.; Akeson, S.; Narzisi, G.; Steinsnyder, Z.; Reeves, C.; Shelton, J.; Kingan, S. B.; Lambert, C.; Bayabyan, P.; Wenger, A. M.; McLaughlin, I. J.; Adamson, A.; Kingsley, C.; Wescott, M.; Kim, Y.; Paten, B.; Park, J.; Violich, I.; Miga, K. H.; Gardner, J.; McNul
10.1101/2024.09.18.613544 — genomics — Posted on 2024-09-22
1725 MutLgamma enforces meiotic crossovers in Arabidopsis thaliana
Durand, S.; Lian, Q.; Solier, V.; Fernandes, J. B.; Mercier, R.
10.1101/2024.09.18.613675 — genetics — Posted on 2024-09-22
1727 Navigating a fine balance: point-mutant cheater viruses disrupt the viral replication cycle
Meir, M.; Kahn, A.; Farage, C.; Maoz, Y.; Harel, N.; Ben Zvi, A.; Segev, S.; Volkov, M.; Yahud, R.; Gophna, U.; Stern, A.
10.1101/2024.09.18.613812 — evolutionary biology — Posted on 2024-09-22
1729 Reversal of elevated Gli3 in Autosomal Recessive Polycystic Kidney Disease does not alter cystogenesis
Russell, L. G.; Kolatsi-Joannou, M.; Wilson, L.; Chandler, J. C.; Perretta Tejedor, N.; Stagg, G.; Price, K. L.; Rowan, C. J.; Crompton, T.; Rosenblum, N. D.; Winyard, P. J.; Long, D. A.
10.1101/2024.09.18.613676 — physiology — Posted on 2024-09-22
1732 Human Mesofluidic Intestinal Model for Studying Transport of Drug Carriers and Bacteria Through a Live Mucosal Barrier
Wang, C.-M.; Oberoi, H. S.; Law, D.; Li, Y.; Kassis, T.; Griffith, L. G.; Breault, D. T.; Carrier, R. L.
10.1101/2024.09.18.613692 — bioengineering — Posted on 2024-09-22
1734 Monocyte-derived cells but not Microglia cause Oxidative Tissue Damage in Neuroinflammation
Villar-Vesga, J.; De Feo, D.; Clement, P.; Ingelfinger, F.; Ulutekin, C.; Kim, J.; Pena-Francesch, M.; Schmidt, K. W.; Meuffels, E.; Bugada, V.; Greis, D.; Pereira, S. A.; Oberbichler, L.; Seehusen, F.; Prisco, F.; Dalvi, U.; Munz, C.; Saab, A. S.; Becher, B.; Mundt, S.
10.1101/2024.09.18.612891 — immunology — Posted on 2024-09-22
1736 Deconvoluted methylation profiles discriminate between closely related melanocytic nevi
Aldea, D.; Macagno, N.; Marechal, E.; Moreno, M.; Romanet, P.; Pertuit, M.; Garcia, J.; Degardin, N.; Mallet, S.; James, I.; Captier, G.; Barlier, A.; Etchevers, H. C.
10.1101/2024.06.11.598516 — cancer biology — Posted on 2024-09-22
1737 Quantitative analysis of non-histone lysine methylation sites and lysine demethylases in breast cancer cell lines
Berryhill, C. A.; Evans, T. N.; Doud, E. H.; Smith-Kinnaman, W. R.; Hanquier, J. N.; Mosley, A. L.; Cornett, E. M.
10.1101/2024.09.18.613658 — cancer biology — Posted on 2024-09-22
1738 Interpretable high-resolution dimension reduction of spatial transcriptomics data by SpaHDmap
Tang, J.; Chen, Z.; Qian, K.; Huang, S.; He, Y.; Yin, S.; He, X.; Ye, B.; Zhuang, Y.; Meng, H.; Xi, J.; Xi, R.
10.1101/2024.09.12.612666 — bioinformatics — Posted on 2024-09-22
1742 Short- and mid-term temporal variability of the human urinary microbiota: an observational cohort study
Tlaskal, V.; Hrbacek, J.; Hanacek, V.; Barankova, P.; Cermak, P.; Zachoval, R.; Dobbler, P. T.
10.1101/2024.06.25.600589 — microbiology — Posted on 2024-09-22
1743 Natural killer cell function is regulated by TGF-β signaling in pregnancy and tumor progression
Yalin, A.; Wang, S.-Y.; Landsberger, T.; Gamliel, M.; Elefant, N.; Kotzur, R.; Goldman-Wohl, D.; David, E.; Molgora, M.; Bhattarai, B.; Cella, M.; Meir-Salame, T.; Gilad, R.; Yagel, S.; Zuk, O.; Colonna, M.; Mandelboim, O.; Amit, I.
10.1101/2024.09.18.613652 — immunology — Posted on 2024-09-22
1744 Broadly Reactive Anti-VHH Antibodies for Characterizing, Blocking, or Activating Nanobody-Based CAR-T Cells
McComb, S.; Dupont, B.; Shepherd, A.; Bennychen, B.; Marcil, A.; Arbabi-Ghahroudi, M.; Tamblyn, L.; Raphael, S.; Sheff, J.; Hussack, G.; Moraitis, A.; Wu, C.; Gadoury, C.; Fortin, A.; Parat, M.; Page, M.; Lippens, J.; Joubert, S.; Lamoureux, L.; Malenfant, F.; Acchione, M.; Pohankova, P.; Schrag, J.; Acel, A.; Maurice, R.; Lefebvre, J.; Coutu, M.; Smith, E.; El Bakkouri, M.; Hill, J. J.; Tremblay, T.-L.; Faulkes, S.; Webb, J.; Zafer, A.; Zhu, Q.; Nguyen, T.; Pon, R. A.; Weeratna, R. D.
10.1101/2024.09.18.613561 — immunology — Posted on 2024-09-22
1745 VirID: Beyond Virus Discovery - An Integrated Platform for Comprehensive RNA Virus Characterization
Yang, Z.; Shan, Y.; Liu, X.; Chen, G.; Pan, Y.; Gou, Q.; Zou, J.; Chang, Z.; Zeng, Q.; Yang, C.; Kong, J.; Sun, Y.; Li, S.; Zhang, X.; Wu, W.; Li, C.; Peng, H.; Holmes, E. C.; Guo, D.; Shi, M.
10.1101/2024.07.05.602175 — bioinformatics — Posted on 2024-09-22
1756 Nucleation limited assembly and polarized growth of a de novo-designed allosterically modulatable protein filament
Shen, H.; Lynch, E. M.; Watson, J. L.; Wu, K.; Bai, H.; Sheffler, W.; Derivery, E.; Kollman, J. M.; Baker, D.
10.1101/2024.09.20.613980 — bioengineering — Posted on 2024-09-22
1760 Targeting cancer-associated glycosylation for adoptive T cell therapy of gastro-intestinal and gynecological cancers
Zingg, A.; Ritschard, R.; Thut, H.; Buchi, M.; Holbro, A.; Oseledchyk, A.; Heinzelmann, V.; Buser, A.; Binder, M.; Zippelius, A.; Mantuano, N. R.; Matter, M.; Laubli, H.
10.1101/2024.09.12.612750 — cancer biology — Posted on 2024-09-22
1762 MRI economics: Balancing sample size and scan duration in brain wide association studies
Ooi, L. Q. R.; Orban, C.; Zhang, S.; Nichols, T.; Tan, T. W. K.; Kong, R.; Marek, S.; Dosenbach, N. U. F.; Laumann, T. O.; Gordon, E. M.; Yap, K. H.; Ji, F.; Chong, J. S. X.; Chen, C.; An, L.; Franzmeier, N.; Roemer, S.; Hu, Q.; Ren, J.; Liu, H.; Chopra, S.; Cocuzza, C. V.; Baker, J. T.; Zhou, J. H.; Bzdok, D.; Eickhoff, S. B.; Holmes, A. J.; Yeo, B. T. T.; Alzheimer's Disease Neuroimaging Initiative,
10.1101/2024.02.16.580448 — neuroscience — Posted on 2024-09-22
1763 Probing the force-from-lipid mechanism with synthetic polymers
Jacobs, M. L.; Steinkühler, J.; Lemley, A.; Larmore, M. J.; Gunnels, T. F.; Ng, L. C. T.; Cologna, S. M.; DeCaen, P. G.; Kamat, N.
10.1101/2022.05.20.492859 — biophysics — Posted on 2024-09-22
1767 Neuroendocrine Control of Intestinal Regeneration Through the Vascular Niche in Drosophila.
Medina, A.; Perochon, J.; Johnson, C.; Polcownuk, S.; Tian, Y.; Yu, Y.; Cordero, J. B.
10.1101/2024.09.10.612352 — developmental biology — Posted on 2024-09-22
1768 Apical Size Reduction by Macropinocytosis Alleviates Tissue Crowding
Bresteau, E.; Suva, E. E.; Revell, C.; Hassan, O. A.; Grata, A.; Sheridan, J.; Mitchell, J.; Arvantis, C.; Korobova, F.; Woolner, S.; Jensen, O. E.; Mitchell, B.
10.1101/2024.08.05.606662 — cell biology — Posted on 2024-09-22
1770 Microbiome determinants of productivity in whiteleg shrimp aquaculture
Shan, X.; Li, K.; Stadler, P.; Borbor, M.; Reyes, G.; Solorzano, R.; Chamorro, E.; Bayot, B.; Cordero, O. X.
10.1101/2024.09.20.614022 — microbiology — Posted on 2024-09-22
1772 Power of self-belief: Growth mindset fosters cognitive development via mesocortical functional coactivation and dynamic reconfiguration
Zhao, Y.; Cui, J.; Zhao, H.; Zeng, Y.; Xu, J.; Chen, M.; Hao, L.; He, Y.; Wang, H.; Wang, Y.; Wang, D.; Han, Z. R.; Tan, S.; Men, W.; Gao, J.; He, Y.; Tao, S.; Dong, Q.; Qin, S.
10.1101/2022.07.11.499525 — neuroscience — Posted on 2024-09-22
1774 Merging metabolic modeling and imaging for screening therapeutic targets in colorectal cancer
Tavakoli, N.; Fong, E. J.; Coleman, A.; Huang, Y.-K.; Bigger, M.; Doche, M. E.; Kim, S.; Lenz, H.-J.; Graham, N. A.; Macklin, P.; Finley, S. D.; Mumenthaler, S. A.
10.1101/2024.05.24.595756 — systems biology — Posted on 2024-09-22
1781 Classifying cell cycle states and a quiescent-like G0 state using single-cell transcriptomics
O'Connor, S. A.; Garcia, L.; Patel, A. P.; Bartelle, B. B.; Hugnot, J.-P.; PADDISON, P.; Plaisier, C. L.
10.1101/2024.04.16.589816 — cell biology — Posted on 2024-09-22
1782 Application of barcode sequencing to increase the throughput and complexity of Plasmodium falciparum genetic screening
Muhwezi, A.; Ghorbal, M.; Sanderson, T.; Ivanova, M.; Ansari, R.; Harper, S.; Wong, W.; Schulte, R.; Girling, G.; Schwach, F.; Bushell, E. S.; Beaver, C.; Billker, O.; Rayner, J. C.
10.1101/2024.09.05.611197 — microbiology — Posted on 2024-09-22
1784 Transcriptomic characterization of human lateral septum neurons reveals conserved and divergent marker genes across species
Phillips, R. A.; Oh, S.; Bach, S. V.; Du, Y.; Miller, R. A.; Kleinman, J. E.; Hyde, T. M.; Hicks, S. C.; Page, S. C.; Martinowich, K.
10.1101/2024.04.22.590602 — neuroscience — Posted on 2024-09-22
1787 Mapping snoRNA-target RNA interactions in an RNA binding protein-dependent manner with chimeric eCLIP
Song, Z.; Bae, B.; Schnabl, S.; Yuan, F.; De Zoysa, T.; Akinyi, M. V.; Le Roux, C. A.; Choquet, K.; Whipple, A. J.; Van Nostrand, E. L.
10.1101/2024.09.19.613955 — genomics — Posted on 2024-09-21
1789 Premature upregulation of miR-92a's target RBFOX2 hijacks PTBP splicing and impairs cortical neuronal differentiation.
Weissbach, S.; Todorov, H.; Schlichtholz, L.; Muehlbauer, S.; Zografidou, L.; Soliman, A.; Lor-Zade, S.; Hartwich, D.; Strand, D.; Vogel, T.; Heine, M.; Gerber, S.; Winter, J.
10.1101/2024.09.20.614071 — genomics — Posted on 2024-09-22
1790 High-risk neuropsychiatric copy number variants are associated with convergent transcriptomic changes in human brain cells
Dugan, G.; Akula, N.; Marenco, S.; Auluck, P.; Raznahan, A.; Liu, S.; DeCasien, A. R.; Xu, Q.; Feng, N.; Kolachana, B.; Jiang, X.; Gregory, M.; Berman, K.; Hoffman, G.; Roussos, P.; Schulmann, A.; McMahon, F.
10.1101/2024.09.19.613680 — genetics — Posted on 2024-09-22
1791 Resolving out of Africa event for Papua New Guinean population using neural network
Mondal, M.; Andre, M.; Pathak, A. K.; Brucato, N.; Ricaut, F.-X.; Metspalu, M.; Eriksson, A.
10.1101/2024.09.19.613861 — evolutionary biology — Posted on 2024-09-22
1793 Widespread selection relaxation in aquatic mammals
Farina, B. M.; Latrille, T.; Salamin, N.; Silvestro, D.; Faurby, S. M.
10.1101/2024.09.18.613479 — evolutionary biology — Posted on 2024-09-21
1794 Functional characterization of N-acetyltransferase 10 (NAT10) in Leishmania mexicana
Rodrigues Maran, S.; Barbosa Leite, A.; Gomes Alves, G.; Souza Bonifacio, B.; Eduardo Gomes Alves, C.; Lourenco Moreira, P. O.; Marques Panessa, G.; Monteiro do Amaral Prado, H.; Montero do Amaral Prado, A.; Cussiol, J. R. R.; Massirer, K. B.; Rodrigues Ferreira, T.; Sacks, D.; Barbieri, C. L.; Santos da Silva, M.; Lima do Monte-Neto, R.; Silvio Moretti, N.
10.1101/2024.09.20.614127 — microbiology — Posted on 2024-09-21
1795 A CYCLIC PEPTIDE TARGETS GLIOBLASTOMA BY BINDING TO ABERRANTLY EXPOSED SNAP25
Arias, A. G.; Tovar-Martinez, L.; Asciutto, E. K.; Mann, A.; Posnograjeva, K.; Simon Gracia, L.; Royo, M.; Haugas, M.; Teesalu, T.; Smulski, C.; Ruoslahti, E.; Scodeller, P.
10.1101/2024.09.18.613627 — cancer biology — Posted on 2024-09-21
1799 Nucleation limited assembly and polarized growth of a de novo-designed allosterically modulatable protein filament
Shen, H.; Lynch, E. M.; Watson, J. L.; Wu, K.; Bai, H.; Sheffler, W.; Derivery, E.; Kollman, J. M.; Baker, D.
10.1101/2024.09.20.613980 — bioengineering — Posted on 2024-09-21
1800 Rubisco packaging and stoichiometric composition of a native β-carboxysome
Sun, Y.; Sheng, Y.; Ni, T.; Ge, X.; Harris, J.; Brownridge, P.; Li, K.; Hardenbrook, N.; Dykes, G.; Rockliffe, N.; Eyers, C.; zhang, p.; Liu, L.-N.
10.1101/2024.09.20.614183 — biochemistry — Posted on 2024-09-21
1802 ERAP1 activity modulates the immunopeptidome but also affects the proteome, metabolism and stress responses in cancer cells
Nikopaschou, M.; Samiotaki, M.; Stylianaki, E.-A.; Krol, K.; Gragera, P.; Raja, A.; Aidinis, V.; Chroni, A.; Fruci, D.; Panayotou, G.; Stratikos, E.
10.1101/2024.09.20.613815 — biochemistry — Posted on 2024-09-21
1805 Phytochromes Enable Social Behavior in Marine Diatoms
Font-Munoz, J. S.; Jaubert, M.; Sourisseau, M.; Tuval, I.; Duchene, C.; Bailleul, B.; Basterretxea, G.; Falciatore, A.
10.1101/2024.09.18.613651 — ecology — Posted on 2024-09-21
1808 Neuralized-like proteins differentially activate Notch ligands
Airich, A.; Gozlan, O.; Seib, E.; Wilschrey, L.-S.; Shaingarten, G. L.; Sprinzak, D.; Klein, T.
10.1101/2024.09.20.614084 — molecular biology — Posted on 2024-09-21
1810 A Cryptic Prophage Transcription Factor Drives Phenotypic Changes via Host Gene Regulation
Lally, P.; Tierrafria, V. H.; Gomez-Romero, L.; Stringer, A. M.; Collado-Vides, J.; Wade, J.; Galagan, J. E.
10.1101/2024.09.21.614188 — microbiology — Posted on 2024-09-21
1811 Bacterial growth under confinement requires transcriptional adaptation to resist metabolite-induced turgor pressure build-up
Le Blanc, L.; Alric, B.; Rollin, R.; Xenard, L.; Ramirez Finn, L.; Goussard, S.; Mazenq, L.; Ingersoll, M. A.; Piel, M.; Tinevez, J.-Y.; Delarue, M.; Dumenil, G.; Bonazzi, D.
10.1101/2024.09.20.614086 — microbiology — Posted on 2024-09-21
1813 Thermal inactivation spectrum of influenza A H5N1 virus in raw milk
Nooruzzaman, M.; Covaleda, L.; Martin, N. H.; Koebel, K. J.; Ivanek, R.; Alcaine, S. D.; Diel, D. G.
10.1101/2024.09.21.614205 — microbiology — Posted on 2024-09-21
1816 Allosteric mechanism of membrane fusion activation in a herpesvirus
Gonzalez-Del Pino, G. L.; Walsh, R. M.; Atanasiu, D.; Cairns, T. M.; Saw, W. T.; Cohen, G. H.; Heldwein, E. E.
10.1101/2024.09.20.610514 — microbiology — Posted on 2024-09-21
1819 UnifiedGreatMod: A New Holistic Modeling Paradigm for Studying Biological Systems on a Complete and Harmonious Scale
Aucello, R.; Pernice, S.; Tortarolo, D.; Calogero, R. A.; Herrera-Rincon, C.; Ronchi, G.; Geuna, S.; Cordero, F.; Lio', P.; Beccuti, M.
10.1101/2024.09.18.613635 — systems biology — Posted on 2024-09-21
1820 Nucleus Pulposus Cell Network Modelling in the Intervertebral Disc
Tseranidou, S.; Segarra-Queralt, M.; Chemorion, F. K.; Le Maitre, C.; Pinero, J.; Noailly, J.
10.1101/2024.09.18.613636 — systems biology — Posted on 2024-09-21
1824 Abstinence from cocaine self-administration promotes microglia pruning of astrocytes which drives cocaine-seeking behavior
Testen, A.; VanRyzin, J. W.; Bellinger, T. J.; Kim, R. W.; Wang, H.; Gastinger, M. J.; Witt, E. A.; Franklin, J. P.; Vecchiarelli, H. A.; Picard, K.; Tremblay, M.-E.; Reissner, K. J.
10.1101/2024.09.20.614128 — neuroscience — Posted on 2024-09-21
1826 A role for acetylcholine in reinforcement learning and decision making under uncertainty
Kurtenbach, H.; Froböse, M. I.; Ort, E.; Bahners, B. H.; Hirschmann, J.; Butz, M.; Schnitzler, A.; Jocham, G.
10.1101/2024.09.20.614105 — neuroscience — Posted on 2024-09-21
1827 Histone deacetylase 5 in prelimbic prefrontal cortex limits context-associated cocaine seeking
Barry, S. M.; Huebschman, J.; DeVries, D. M.; McCue, L. M.; Tsvetkov, E.; Anderson, E. M.; Siemsen, B. M.; Scofield, M. D.; Taniguchi, M.; Penrod, R. D.; Cowan, C. W.
10.1101/2024.09.21.614125 — neuroscience — Posted on 2024-09-21
1833 Concurrent large-scale brain dynamics during the emotional face matching task and their relation to behavior and mental health
Korponay, C.; Cohen-Gilbert, J. E.; Kumar, P.; Harnett, N. G.; Medina, A. A.; Forester, B. P.; Ressler, K. J.; Beckmann, C. F.; Harper, D. G.; Nickerson, L. D.
10.1101/2024.09.21.613739 — neuroscience — Posted on 2024-09-21
1834 Spinal neuron diversity scales exponentially with swim-to-limb transformation during frog metamorphosis
Vijatovic, D.; Toma, F. A.; Harrington, Z. P. M.; Sommer, C.; Hauschild, R.; Trevisan, A. J.; Chapman, P.; Julseth, M. J.; Brenner-Morton, S.; Gabitto, M. I.; Dasen, J. S.; Bikoff, J. B.; Sweeney, L. B.
10.1101/2024.09.20.614050 — neuroscience — Posted on 2024-09-21
1836 hiPSC-derived astrocytes from individuals with schizophrenia promote alterations in phagocytosis and chemotaxis of microglial-like cells
Cardozo, P. L.; Lee, C.-Y.; Lacerda, J. P. S.; Fahel, J. S.; Trindade, P.; Vitoria, G.; Chicaybam, L.; Cordeiro, R. C.; de Faria, I. J. S.; Silva, N. C.; Todjro, Y. M. H.; Maciel, J. C. d. P.; Bonamino, M. H.; Vieira, L. B.; Cruz, B. F.; Nicolato, R.; Brennand, K. J.; Rehen, S. K.; Ribeiro, F. M.
10.1101/2024.09.20.614161 — neuroscience — Posted on 2024-09-21
1837 Vocal Call Locator Benchmark (VCL) for localizing rodent vocalizations from multi-channel audio
Peterson, R. E.; Tanelus, A.; Ick, C.; Mimica, B.; Francis, N.; Ivan, V. J.; Choudhri, A.; Falkner, A.; Murthy, M.; Schneider, D. M.; Sanes, D. H.
10.1101/2024.09.20.613758 — neuroscience — Posted on 2024-09-21
1840 Advancing Clinical Response Against Glioblastoma: Evaluating SHP1705 CRY2 Activator Efficacy in Preclinical Models and Safety in Phase I Trials
Chan, P.; Nagai, Y.; Wu, Q.; Hovsepyan, A.; Mkhitaryan, S.; Wang, J.; Karapetyan, G.; Kamenecka, T.; Solt, L. A.; Cope, J.; Moats, R. A.; Hirota, T.; Rich, J. N.; Kay, S. A.
10.1101/2024.09.17.613520 — cancer biology — Posted on 2024-09-21
1844 A human homolog of SIR2 antiphage proteins mediates immunity via the TLR pathway
Bonhomme, D.; Vaysset, H.; Ednacot, E. M. Q.; Rodrigues, V.; Cury, J.; Hernandez Trejo, V.; Benaroch, P.; Morehouse, B. R.; Bernheim, A.; Poirier, E. Z.
10.1101/2024.09.18.613514 — immunology — Posted on 2024-09-21
1846 Distinct duration and diet dependent lipid profiles and renal complicationsin GCK-MODY
Huang, Y.; Fan, Y.; Liu, Y.; Liu, X.; Li, W.; Yang, Y.; Zhang, Z.; Ma, S.; shuhui, j.; Chen, S.; Shu, H.; Feng, W.; Wang, K.; He, Q.; Qi, W.; Fan, Y.; Li, X.; Liu, M.
10.1101/2024.09.17.613598 — physiology — Posted on 2024-09-21
1847 Integration of metabolomic and transcriptomic analyses reveals novel regulatory functions of the ChREBP transcription factor in energy metabolism
An, J.; Astapova, I.; Zhang, G.; Cangelosi, A. L.; Ilkayeva, O.; Marchuk, H.; Muehlbauer, M. J.; George, T.; Brozinick, J. T.; Herman, M. A.; Newgard, C. B.
10.1101/2024.09.17.613577 — physiology — Posted on 2024-09-21
1849 Truncated Complement Factor H Y402 Gene Therapy Cures C3 Glomerulonephritis
Chew, L. A.; Grigsby, D.; Hester, C. G.; Amason, J.; McPherson, W. K.; Flynn, E. J.; Visel, M.; Flannery, J. G.; Bowes Rickman, C.
10.1101/2024.09.17.613471 — pathology — Posted on 2024-09-21
1850 CDK4 inactivation balances resistance to apoptosis with heightened metabolic sensitivity in triple negative breast cancer cells
Ziegler, D. V.; Leal-Esteban, L.; Parashar, K.; Castro, W.; Zanou, N.; Huber, K.; Lopez-Alcala, J.; Berney, X. P.; Malagon, M. M.; Roger, C.; Berger, M.-A.; Paone, G.; Gallart-Ayala, H.; Ivanisevic, J.; Irving, M.; Fajas, L.
10.1101/2024.09.17.613455 — cancer biology — Posted on 2024-09-21
1852 Tenascin-C in the early lung cancer tumor microenvironment promotes progression through integrin activation and FAK
Mendoza, M. C.; Samson, S. C.; Rojas, A.; Zitnay, R. G.; Carney, K. R.; Hettinga, W.; Shaelling, M. C.; Sicard, D.; Zhang, W.; Gilbert-Ross, M.; Dy, G. K.; Cavnar, M. J.; Furqan, M.; Browning, R. F.; Naqash, A. R.; Schneider, B. P.; Tarhini, A.; Tschumperlin, D. J.; Venosa, A.; Marcus, A. I.; Emerson, L. L.; Spike, B. T.; Knudsen, B.
10.1101/2024.09.17.613509 — cancer biology — Posted on 2024-09-21
1855 The dynamics of capillary flow in an open-channel system featuring trigger valves
Tokihiro, J. C.; Robertson, I. H.; Shin, A.; Gregucci, D.; Michelini, E.; Nicholson, T. M.; Olanrewaju, A.; Theberge, A. B.; Berthier, J.; Berthier, E.
10.1101/2024.09.17.613325 — bioengineering — Posted on 2024-09-21
1856 Characterizing human CMV-specific CD8+ T cells using multi-layer single-cell omics
Gemuend, I.; Bonaguro, L.; Becker, M.; Mueller, S.; Joos, C.; De Domenico, E.; Aschenbrenner, A.; Schultze, J. L.; Moosmann, A. L.; Beyer, M. D.
10.1101/2024.09.17.613216 — genomics — Posted on 2024-09-21
1858 Clonal dynamics and somatic evolution of haematopoiesis in mouse
Kapadia, C. D.; Williams, N.; Dawson, K. J.; Watson, C.; Yousefzadeh, M. J.; Le, D.; Nyamondo, K.; Cagan, A.; Waldvogel, S.; De La Fuente, J.; Leongamornlert, D.; Mitchell, E.; Florez, M. A.; Aguilar, R.; Martell, A.; Guzman, A.; Harrison, D.; Niedernhofer, L. J.; King, K. Y.; Campbell, P. J.; Blundell, J.; Goodell, M. A.; Nangalia, J.
10.1101/2024.09.17.613129 — genomics — Posted on 2024-09-21
1859 Varying recombination landscapes between individuals are driven by polymorphic transposable elements
Huang, Y.; Gao, Y.; Ly, K.; Lin, L.; Lambooij, J. P.; King, E. G.; Janssen, A.; Wei, K.; Lee, G. Y. C.
10.1101/2024.09.17.613564 — genomics — Posted on 2024-09-21
1860 The evolution, diversity, and genetic architecture of sex in waterhemp (Amaranthus tuberculatus)
Kreiner, J. M.; Todesco, M.; Bercovich, N.; Gong, Y.; Elphinstone, C.; Tranel, P. J.; Rieseberg, L. H.; Wright, S. I.
10.1101/2024.09.17.613486 — evolutionary biology — Posted on 2024-09-21
1865 Glutamine availability regulates cDC subsets in tissue
Lobel, G. P.; Han, N.; Arocho, W. A. M.; Silber, M.; Shoush, J.; Noji, M. C.; To, T. K. J.; Zhai, L.; Lesner, N. P.; Simon, M. C.; Haldar, M.
10.1101/2024.09.17.613574 — immunology — Posted on 2024-09-21
1866 Quantitative proteomics reveals differential extracellular vesicle cargo from M1 and M2 monocyte-derived human macrophages
Pantazi, P.; Clements, T.; Parsons, H. T.; Kaforou, M.; Heesom, K. J.; Bennet, P. R.; Guller, S.; Abrahams, V. M.; Holder, B.
10.1101/2024.09.17.613483 — immunology — Posted on 2024-09-21
1867 High-dimensional Ageome Representations of Biological Aging across Functional Modules
Ying, K.; Tyshkovskiy, A.; Chen, Q.; Latorre-Crespo, E.; Zhang, B.; Liu, H.; Matei-Dedu, B.; Poganik, J. R.; Moqri, M.; Kirschner, K.; Lasky-Su, J.; Gladyshev, V. N.
10.1101/2024.09.17.613599 — systems biology — Posted on 2024-09-21
1869 Single-cell Landscape of Immune Cells in Blood and Skin in Psoriasis
Deng, J.; Nordkamp, M. O.; Ye, S.; Ye, J.; Balak, D.; Yu, W.; Radstake, T.; Borghans, J. A. M.; Lu, C.; Pandit, A.; Gerritsen, B.
10.1101/2024.09.17.613463 — systems biology — Posted on 2024-09-21
1870 Ex vivo DHA supplementation suppresses prostaglandin E2 formation in primary human macrophages
Kirchhoff, R.; Kampschulte, N.; Rothweiler, C.; Rohwer, N.; Weylandt, K. H.; Schebb, N. H.
10.1101/2024.09.17.613409 — physiology — Posted on 2024-09-21
1871 Inactivity-mediated molecular adaptations: insights from a novel pre-clinical model of physical activity reduction
Meyer, A.; Kim, N.; Nguyen, M.; Misch, M.; Marmo, K.; Dowd, J.; Will, C.; Janosevic, M.; Stephenson, E. J.
10.1101/2024.09.17.613551 — physiology — Posted on 2024-09-21
1872 Antipsychotic-like effects of the selective Rho-kinase 2 inhibitor KD025 in genetic and pharmacological mouse models of schizophrenia
Tanaka, R.; Liao, J.; Liu, Y.; Zhu, W.; Fukuzawa, K.; Kondo, M.; Sawahata, M.; Mori, D.; Mouri, A.; Kubota, H.; Tachibana, D.; Kobayashi, Y.; Matsuzaki, T.; Nagai, T.; Nabeshima, T.; Kaibuchi, K.; Ozaki, N.; Mizoguchi, H.; Yamada, K.
10.1101/2024.09.16.613372 — pharmacology and toxicology — Posted on 2024-09-21
1873 A Kinetic Scout Approach Accelerates Targeted Protein Degrader Development
Fan, A. T.; Gadbois, G. E.; Huang, H.-T.; Jiang, J.; Sigua, L. H.; Smith, E. R.; Wu, S.; Dunne-Dombrink, K.; Goyal, P.; Tao, A. J.; Sellers, W. B.; Fischer, E. S.; Donovan, K. A.; Ferguson, F.
10.1101/2024.09.17.612508 — pharmacology and toxicology — Posted on 2024-09-21
1874 Retinal ganglion cell vulnerability to pathogenic tau in Alzheimer's disease
Davis, M. R.; Robinson, E.; Koronyo, Y.; Salobrar-Garcia, E.; Rentsendorj, A.; Gaire, B. P.; Mirzaei, N.; Kayed, R.; Sadun, A. A.; Ljubimov, A. V.; Schneider, L. S.; Hawes, D.; Black, K. L.; Fuchs, D.-T.; Koronyo-Hamoui, M.
10.1101/2024.09.17.613293 — pathology — Posted on 2024-09-21
1875 Fibroblasts Regulate the Transformation Potential of Human Papillomavirus-positive Keratinocytes
James, C. D.; Lewis, R. L.; Witt, A. J.; Carter, C.; Rais, N. M.; Wang, X.; Bristol, M. L.
10.1101/2024.09.16.613347 — cancer biology — Posted on 2024-09-21
1876 Myofiber-specific FoxP1 knockout protects against pancreatic cancer-induced muscle wasting in male but not female mice.
Schonk, M. M.; Ducharme, J. B.; Neyroud, D.; Nosacka, R. L.; Tucker, H. O.; Judge, S. M.; Judge, A. R.
10.1101/2024.09.17.613547 — cancer biology — Posted on 2024-09-21
1877 Prediction and functional interpretation of inter-chromosomal genome architecture from DNA sequence with TwinC
Jha, A.; Hristov, B.; Wang, X.; Wang, S.; Greenleaf, W.; Kundaje, A.; Aiden, E. L.; Bertero, A.; Noble, W. S.
10.1101/2024.09.16.613355 — bioinformatics — Posted on 2024-09-21
1878 Bolero: a dedicated workflow to decipher Hepatitis B virus transcriptome from long-reads sequencing method coupled to 5RACE amplification of transcripts
Grand, X.; Giraud, G.; Rifki, A.; Paturel, A.; Bousquet, D.; Roca Suarez, A. A.; Bourgeois, C.; Levrero, M.; Zoulim, F.; Testoni, B.
10.1101/2024.09.17.613398 — bioinformatics — Posted on 2024-09-21
1879 Detection of statistically robust interactions from diverse RNA-DNA ligation data
Zehr, S.; Seredinski, S.; Walsh, E. C.; Bonetti, A.; Leisegang, M. S.; Brandes, R. P.; Schulz, M. H.; Warwick, T.
10.1101/2024.09.17.610461 — bioinformatics — Posted on 2024-09-21
1881 Calibration of additional computational tools expands ClinGen recommendation options for variant classification with PP3/BP4 criteria
Bergquist, T.; Stenton, S. L.; Nadeau, E. A. W.; Byrne, A. B.; Greenblatt, M. S.; Harrison, S. M.; Tavtigian, S. V.; O'Donnell-Luria, A.; Biesecker, L. G.; Radivojac, P.; Brenner, S. E.; Pejaver, V.; ClinGen Sequence Variant Interpretation Working Group,
10.1101/2024.09.17.611902 — bioinformatics — Posted on 2024-09-21
1883 Modeling integration site data for safety assessment with MELISSA
Lin, T.-Y.; Ceoldo, G.; House, K.; Welty, M.; Dang, T. T.; Klatt, D.; Brendel, C.; Murphy, M. P.; Cornetta, K.; Pellin, D.
10.1101/2024.09.16.613352 — bioinformatics — Posted on 2024-09-21
1886 The MAASWERP study: An international, comparative case study on measuring biomechanics of the aged murine aorta
Neutel, C. H. G.; van der Laan, K. W. F.; Wesley, C. D.; Krüger, D. N.; Pencheva, M. G.; Schalkwijk, C. G.; De Meyer, G. R. Y.; Martinet, W.; Delhaas, T.; Reesink, K. D.; Giudici, A.; Guns, P.-J.; Spronck, B.
10.1101/2024.09.17.613423 — bioengineering — Posted on 2024-09-21
1887 Longitudinal analysis of glioblastoma response to oncolytic HSV1 guides PLX3397 combination for enhanced viral permissiveness
Ito, H.; Shono, N.; Zagami, C.; Kim, M. J.; Quazim, A. A.; McLaughlin, E.; Goins, W. F.; Fernandez, S.; Chiocca, E. A.; Nakashima, H.
10.1101/2024.09.17.613527 — bioengineering — Posted on 2024-09-21
1889 Evaluation of genomic and phenomic prediction for application in apple breeding
Jung, M.; Hodel, M.; Knauf, A.; Kupper, D.; Neuditschko, M.; Bühlmann-Schütz, S.; Studer, B.; Patocchi, A.; Broggini, G. A.
10.1101/2024.09.17.613481 — genomics — Posted on 2024-09-21
1896 TIRTL-seq: Deep, quantitative, and affordable paired TCR repertoire sequencing
Pogorelyy, M. V.; Kirk, A. M.; Adhikari, S.; Minervina, A. A.; Sundararaman, B.; Vegesana, K.; Brice, D. C.; Scott, Z. B.; SJTRC Study Team, ; Thomas, P. G.
10.1101/2024.09.16.613345 — immunology — Posted on 2024-09-21
1897 Post-transcriptional control of homeostatic B- cell signalling by HuR is required for innate B cell maintenance and function.
Capitan-Sobrino, D.; Mouysset, M.; Maloudi, O.; Aubert, Y.; Osma-Garcia, I. C.; Nestor-Martin, M.; Nguyen, T.-M. M.; Dunga, G.; Diaz-Munoz, M. D.
10.1101/2024.09.17.611791 — immunology — Posted on 2024-09-21
1898 Coral hosts actively accumulate inorganic carbon for Symbiodiniaceae to maintain symbiotic relationships
Zhang, B.; Tang, S.; Liu, L.; Xu, M.; Liu, Y.; Zhu, J.; Xiao, W.; Bi, H.; Zhou, J.; Benfield, M. C.; Cai, Z.
10.1101/2024.05.31.596804 — ecology — Posted on 2024-09-21
1905 SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF Resulting in Drastic Soluble Protein Depletion
Christ, W.; Kapell, S.; Sobkowiak, M. J.; Mermelekas, G.; Evertsson, B.; Sork, H.; Saher, O.; Bazaz, S.; Gustafsson, O.; Cardenas, E. I.; Villa, V.; Ricciarelli, R.; Sandberg, J. K.; Bergquist, J.; Sturchio, A.; Svenningsson, P.; Malm, T.; Espay, A. J.; Pernemalm, M.; Linden, A.; Klingstrom, J.; EL Andaloussi, S.; Ezzat, K.
10.1101/2022.09.15.508120 — neuroscience — Posted on 2024-09-21
1906 Sox9 prevents retinal degeneration and is required for limbal stem cell differentiation in the adult mouse eye
Hurtado, A.; Lopez-Soriano, V.; Lao, M.; Celis-Barroso, M. A.; Lazuen, P.; Chacon-de-Castro, A.; Ramirez-Casas, Y.; Alaminos, M.; Collinson, J. M.; Burgos, M.; Jimenez, R.; Carmona, F. D.; Barrionuevo, F. J.
10.1101/2024.09.19.613969 — developmental biology — Posted on 2024-09-21
1907 Ecophysiological Behaviour Of Major Fusarium Species In Response To Combinations Of Temperature And Water Activity Constraints
Foulongne-Oriol, M.; Garcia, M.-A.; Mahmoud, R.; Bancal, M.-O.; Bancal, P.; Bernillon, S.; Pinson-Gadais, L.; Richard-Forget, F.
10.1101/2024.09.19.613940 — microbiology — Posted on 2024-09-21
1908 Preventing Inappropriate Signals Pre- and Post-Ligand Perception by a Toggle-Switch Mechanism of ERECTA
Chen, L.; Maes, M.; Cochran, A. M.; Avila, J. R.; Derbyshire, P.; Sklenar, J.; Haas, K. M.; Villen, J.; Menke, F.; Torii, K. U.
10.1101/2024.09.20.612365 — plant biology — Posted on 2024-09-21
1909 Low maternal plasma apelin in the second trimester is associated with adverse pregnancy outcome in severe, early-onset fetal growth restriction
Braun, N.; Bethell, K.; Chaloner, L.; Maksym, K.; Spencer, R. N.; Maguire, J. J.; Davenport, A.; EVERREST consortium, ; David, A. L.; Vaughan, O. R.
10.1101/2024.09.19.613895 — physiology — Posted on 2024-09-21
1910 Biomechanical Evaluation of Temporomandibular Joint Implants Under Complete Mastication Cycle
Ghosh, R.; Chandra, G.; Verma, V.; Kaur, K.; Roychoudhury, A.; Mukherjee, S.; Chawla, A.; Mukherjee, K.
10.1101/2024.08.26.609607 — bioengineering — Posted on 2024-09-21
1911 Haplotype-resolved assemblies provide insights into genomic makeup of the oldest grapevine cultivar (Munage) in Xinjiang
Zhong, H.; Shi, x.; Zhang, F.; Wang, X.; yadav, v.; Zhou, X.; Cao, s.; Zhang, S.; Zhang, C.; Qiao, J.; Liu, Z.; Zhang, y.; Liu, y.; Wang, H.; Xue, h.; Zhang, M.; Zhang, T.-H.; Zhou, Y.; Wu, X.; Xiao, H.
10.1101/2024.09.11.612401 — genomics — Posted on 2024-09-21
1913 Beta-1,6-glucan plays a central role in the structure and remodeling of the bilaminate fungal cell wall
Bekirian, C.; Valsecchi, I.; Bachellier-Bassi, S.; Scandola, C.; Guijarro, J. I.; Chauvel, M.; Mourer, T.; Gow, N.; Aimanianda Bopaiah, V. K.; d'Enfert, C.; Fontaine, T.
10.1101/2024.06.30.601427 — microbiology — Posted on 2024-09-21
1914 T-cell receptors identified by a personalized antigen-agnostic screening approach target shared neoantigen KRAS Q61H
Lennerz, V.; Doppler, C.; Fatho, M.; Droege, A.; Schaper, S.; Gennermann, K.; Genzel, N.; Plassmann, S.; Weismann, D.; Lukowski, S. W.; Bents, D.; Beushausen, C.; Kriese, K.; Herbst, H.; Seitz, V.; Hammer, R.; Adam, P. J.; Eggeling, S.; Woelfel, C.; Woelfel, T.; Hennig, S.
10.1101/2024.09.19.612910 — immunology — Posted on 2024-09-21
1915 Qualitative EEG abnormalities signal a shift towards inhibition-dominated brain networks. Results from the EU-AIMS LEAP studies
Juarez-Martinez, E. L.; Avramiea, A.-E.; Garces, P.; Hipp, J. F.; Poil, S.-S.; Diachenko, M.; Mansvelder, H.; Jones, E. J.; Mason, L.; Murphy, D.; Loth, E.; Oakley, B.; Charman, T.; Banaschewski, T.; Oranje, B.; Buitelaar, J.; Bruining, H.; Linkenkaer-Hansen, K.
10.1101/2024.09.19.613847 — neuroscience — Posted on 2024-09-21
1917 Biochemical and neurophysiological effects of deficiency of the mitochondrial import protein TIMM50
Paz, E.; Jain, S.; Gottfried, I.; Staretz-Chacham, O.; Mahajnah, M.; Bagchi, P.; Seyfried, N.; Ashery, U.; Azem, A.
10.1101/2024.05.20.594480 — biochemistry — Posted on 2024-09-21
1920 Actin-based deformations of the nucleus control multiciliated ependymal cell differentiation.
Basso, M.; Mahuzier, A.; Ali, S. K.; Marty, A.; Faucourt, M.; Lennon-Dumenil, A.-M.; Srivastava, A.; Khoury Damaa, M.; Bankole, A.; Meunier, A.; Yamada, A.; Plastino, J.; Spassky, N.; Delgehyr, N.
10.1101/2023.10.13.562225 — developmental biology — Posted on 2024-09-21
1921 Redirecting full-length FLT1 expression towards its soluble isoform promotes postischemic angiogenesis
Bundalo, M.; Vorlova, S.; Ulrich, J.; Barbieri, R.; Richter, L.; Hoena, L.; Egg, M.; Bock, J.; Schaefer, S.; Amezaga Sole, N.; Rosa, A.; Rizzo, G.; Cochain, C.; Kastenmueller, W.; Henke, E.; Skryabin, B. V.; Rozhdestvensky, T. S.; Wildgruber, M.; Lorenz, K.; Kuhn, M.; Zernecke, A.
10.1101/2024.09.19.613989 — cell biology — Posted on 2024-09-21
1922 A system for functional studies of the major virulence factor of malaria parasites
Cronshagen, J.; Allweier, J.; Mesen-Ramirez, P.; Staecker, J.; Vaaben, A. V.; Ramon-Zamorano, G.; Naranjo, I.; Ofori, S.; Jansen, P. W.; Hornebeck, J.; Kieferle, F.; Murk, A.; Martin, E.; Castro-Pena, C.; Bartfai, R.; Lavstsen, T.; Bruchhaus, I.; Spielmann, T.
10.1101/2024.04.30.591946 — microbiology — Posted on 2024-09-21
1923 TCR transgenic clone selection guided by immune receptor analysis and single cell RNA expression of polyclonal responders
Debeuf, N.; Lameire, S.; Vanheerswynghels, M.; Deckers, J.; De Wolf, C.; Toussaint, W.; Verbeke, R.; Verstaen, K.; Hammad, H.; Vanhee, S.; Lambrecht, B. N.
10.1101/2024.03.27.586931 — immunology — Posted on 2024-09-21
1925 Ultra-low-field paediatric MRI in low- and middle-income countries: super-resolution using a multi-orientation U-Net
Baljer, L.; Zhang, Y.; Bourke, N. J.; Donald, K. A.; Bradford, L. E.; Ringshaw, J. E.; Williams, S. R.; Deoni, S. C.; Williams, S. C.; Khula SA Study Team, ; Vasa, F.; Moran, R. J.
10.1101/2024.02.16.580639 — neuroscience — Posted on 2024-09-21
1928 Amino Acid and Glucose Fermentation Maintain ATP Content in Mouse and Human Malignant Glioma Cells
Lee, D. C.; Ta, L.; Mukherjee, P.; Duraj, T.; Domin, M.; Greenwood, B.; Karmacharya, S.; Narain, N. R.; Kiebish, M.; Chinopoulos, C.; Seyfried, T. N.
10.1101/2024.04.18.589922 — cancer biology — Posted on 2024-09-21
1932 Modification and Analysis of Context-Specific Genome-Scale Metabolic Models: Methane-Utilizing Microbial Chassis as a Case Study
Kulyashov, M. A.; Hamilton, R.; Afshin, Y.; Kolmykov, S. K.; Sokolova, T. S.; Khlebodarova, T. M.; Kalyuzhnaya, M. G.; Akberdin, I. R.
10.1101/2024.09.16.613288 — systems biology — Posted on 2024-09-20
1934 Therapeutic modulation of ROCK overcomes metabolic adaptation of cancer cells to OXPHOS inhibition and drives synergistic anti-tumor activity
Blazanin, N.; Laing, X.; Mahmud, I.; Kim, E.; Martinez, S.; Tan, L.; Anvar, N. E.; Chan, W.; Ha, M. J.; Qudratullah, M.; Minelli, R.; Peoples, M.; Lorenzi, P.; Hart, T.; Lissanu, Y.
10.1101/2024.09.16.613317 — cancer biology — Posted on 2024-09-20
1937 Tricuspid valve maladaptation in sheep with biventricular heart failure: The posterior and septal leaflets
Kostelnik, C. J.; Meador, W. D.; Lin, C.-Y.; Mathur, M.; Malinowski, M.; Jazwiec, T.; Malinowska, Z.; Piekarska, M. L.; Gaweda, B.; Timek, T. A.; Rausch, M. K.
10.1101/2024.09.16.613284 — bioengineering — Posted on 2024-09-20
1939 An intrinsically disordered RNA-binding region provides local target selectivity and is essential for LARP6 function.
Capraro, F.; Abis, G.; Karimzadeh, M.; Masino, L.; Barley, A.; Bui, T. T. T.; Goodarzi, H.; Conte, M. R.; Mardakheh, F. K.
10.1101/2024.09.20.614075 — biochemistry — Posted on 2024-09-20
1941 Dynamic metal coordination controls chemoselectivity in radical halogenases
Kissman, E. N.; Kipouros, I.; Slater, J. W.; Stone, E. A.; Yang, A. Y.; Braun, A.; Ensberg, A. R.; Whitten, A. M.; Chatterjee, K.; Bogacz, I.; Yano, J.; Bollinger, J. M.; Chang, M. C. Y.
10.1101/2024.09.19.613983 — biochemistry — Posted on 2024-09-20
1947 Deep learning uncovers sequence-specific amplification bias in multi-template PCR
Gimpel, A. L.; Fan, B.; Chen, D.; Wolfle, L. O. D.; Horn, M.; Meng-Papaxanthos, L.; Antkowiak, P. L.; Stark, W. J.; Christen, B.; Borgwardt, K.; Grass, R. N.
10.1101/2024.09.20.614030 — molecular biology — Posted on 2024-09-20
1950 Involvement of 5' and 3' UTRs on SARS-CoV-2 Genome Packaging
Zhang, Z.; Yang, K.; Shao, F.; Shen, W.; Li, P.; Zhang, Y.; Xu, J.; Wang, C.; Xie, D.; Yu, G.; Zhang, J.; Zhao, Z.; Zhang, Y.
10.1101/2024.09.19.611578 — microbiology — Posted on 2024-09-20
1951 Mpox mRNA-1769 Vaccine Inhibits Orthopoxvirus Replication at Intranasal, Intrarectal, and Cutaneous Sites of Inoculation
Cotter, C. A.; Ignacio, M. A.; Americo, J. L.; Earl, P. L.; Mucker, E. M.; Hooper, J. W.; Frey, T. R.; Carfi, A.; Freyn, A. W.; Moss, B.
10.1101/2024.09.19.613928 — microbiology — Posted on 2024-09-20
1953 1 Microbiome determinants of productivity in whiteleg shrimp aquaculture
Shan, X.; Li, K.; Stadler, P.; Borbor, M.; Reyes, G.; Solorzano, R.; Chamorro, E.; Bayot, B.; Cordero, O. X.
10.1101/2024.09.20.614022 — microbiology — Posted on 2024-09-20
1955 Klebsiella pneumoniae isolated from the intestines of Tenebrio molitor larvae (Coleoptera: Tenebrionidae) that consume expanded polystyrene
Caruajulca-Marin, L.; Huaman-Ventura, K.; Purihuaman, M. S.; Caro-Castro, J.; Barturen-Quispe, A.; Vasquez-Llanos, S.; Carreno-Farfan, C.
10.1101/2024.09.20.613978 — microbiology — Posted on 2024-09-20
1956 ICOS limits memory-like properties and function of exhausted PD-1+ CD8 T cells
Humblin, E.; Korpas, I.; Prokhnevska, N.; Vaidya, A.; Lu, J.; van der Heide, V.; Filipescu, D.; Bobrowski, T.; Marks, A.; Park, M. D.; Bernstein, E.; Brown, B. D.; Lujambio, A.; Dominguez-Sola, D.; Rosenberg, B. R.; Kamphorst, A. O.
10.1101/2024.09.16.611518 — immunology — Posted on 2024-09-20
1957 Hemoglobin alpha is a redox-sensitive mitochondrial-related protein in T-lymphocytes
Reed, E. C.; Silva, V. A.; Giebel, K. R.; Natour, T.; Lauten, T. H.; Jojo, C. N.; Schleiker, A. E.; Case, A. J.
10.1101/2024.09.16.613298 — immunology — Posted on 2024-09-20
1958 Working memory predicts long-term recognition of auditory sequences: Dissociation between confirmed predictions and prediction errors
Bonetti, L.; Risgaard Olsen, E.; Carlomagno, F.; Serra, E.; Szabo, S. A.; Klarlund, M.; Andersen, M.; Frausing, L.; Vuust, P.; Brattico, E.; Kringelbach, M. L.; Fernandez-Rubio, G.
10.1101/2024.09.20.614110 — neuroscience — Posted on 2024-09-20
1960 EFFECTS OF SPINAL TRANSECTION AND LOCOMOTOR SPEED ON MUSCLE SYNERGIES OF THE CAT HINDLIMB
Klishko, A.; Harnie, J.; Hanson, C. E.; Rahmati, S. M.; Rybak, I. A.; Frigon, A.; Prilutsky, B. I.
10.1101/2024.09.19.613891 — neuroscience — Posted on 2024-09-20
1963 Hippocampal γCaMKII dopaminylation promotes synaptic-to-nuclear signaling and memory formation
Stewart, A. F.; Fulton, S. L.; Durand-de Cuttoli, R.; Thompson, R. E.; Chen, P.-J.; Brindley, E.; Cetin, B.; Farrelly, L. A.; Futamura, R.; Claypool, S.; Bastle, R. M.; Di Salvo, G.; Peralta, C.; Molina, H.; Baljinnyam, E.; Marro, S. G.; Russo, S. J.; Devita, R. J.; Muir, T. W.; Maze, I.
10.1101/2024.09.19.613951 — neuroscience — Posted on 2024-09-20
1964 A unified rodent atlas reveals the cellular complexity and evolutionary divergence of the dorsal vagal complex
Hes, C.; Tomlinson, A. J.; Michielsen, L.; Murdoch, H. J.; Soltani, F.; Kokoeva, M.; Sabatini, P. V.
10.1101/2024.09.19.613879 — neuroscience — Posted on 2024-09-20
1965 Chromatin remodeler BRG1 recruits huntingtin to repair DNA double-strand breaks in neurons
Pradhan, S.; Bush, K.; Zhang, N.; Pandita, R. K.; Tsai, C.-L.; Smith, C.; Pandlebury, D. F.; Gaikwad, S.; Leonard, F.; Nie, L.; Tao, A.; Russell, W.; Yuan, S.; Choudhary, S.; Ramos, K. S.; Elferink, C.; Wairkar, Y. P.; Tainer, J. A.; Thompson, L. M.; Pandita, T. K.; Sarkar, P. S.
10.1101/2024.09.19.613927 — neuroscience — Posted on 2024-09-20
1966 Functional localization of visual motion area FST in humans
Wen, P.; Ezzo, R.; Thompson, L. W.; Rosenberg, A.; Landy, M. S.; Rokers, B.
10.1101/2024.09.19.614014 — neuroscience — Posted on 2024-09-20
1967 Exercise Evokes Retained Motor Performance without Neuroprotection in a Mouse Model of Parkinson's Disease
Skelton, H. M.; Hyman, N.; Fernandez, A.; Acerbo, E.; Scott, M.; Berglund, K.; Gutekunst, C.-A.; Gross, R. E.
10.1101/2024.09.20.614034 — neuroscience — Posted on 2024-09-20
1969 A neural mechanism for compositional generalization of structure in humans
Luettgau, L.; Chen, N.; Erdmann, T.; Veselic, S.; Moran, R.; Kurth-Nelson, Z.; Dolan, R. J.
10.1101/2024.09.20.614119 — neuroscience — Posted on 2024-09-20
1972 Modulating DNA Polα Enhances Cell Reprogramming Across Species
Ranjan, R.; Ma, B.; Gleason, R. J.; Liao, Y.; Bi, Y.; Davis, B. E. M.; Yang, G.; Clark, M.; Mahajan, V.; Condon, M.; Broderick, N. A.; Chen, X.
10.1101/2024.09.19.613993 — developmental biology — Posted on 2024-09-20
1973 Integrating collecting systems in kidney organoids through fusion of distal nephron to ureteric bud.
Shi, M.; Crouse, B.; Sundaram, N.; Shakked, N. P.; Ester, L.; Zhang, W.; Janakiram, V.; Kopan, R.; Helmrath, M.; Bonventre, J. V.; McCracken, K. W.
10.1101/2024.09.19.613645 — developmental biology — Posted on 2024-09-20
1974 Novel insights into Emx2 and Dmrta2 cooperation during cortex development and evidence for Dmrta2 function in choroid plexus
Anirudhan, J.; Shen, X.; Szemes, T.; Dieu, M.; Azouz, A.; Conrard, L.; Doumont, G.; Sitte, M.; Achouri, Y.; Kricha, S.; Salinas-Riester, G.; Renard, P.; Bellefroid, E.
10.1101/2024.09.19.613943 — neuroscience — Posted on 2024-09-20
1975 Morphological profiling in human dopaminergic neurons identifies mitochondrial uncoupling as a neuroprotective effect
Gorgogietas, V.; Weiss, A.; Cousin, L.; Hoffmann, D.; Schmitt, K.; Ogier, A.; Barbuti, P. A.; Santos, B. F. R.; Boussaad, I.; Wittich, A.; Zaliani, A.; Pless, O.; Krueger, R.; Sommer, P.; Wilbertz, J. H.
10.1101/2024.09.19.613945 — neuroscience — Posted on 2024-09-20
1976 The Cellular and Extra-Cellular Proteomic Signature of Human Dopaminergic Neurons Carrying the LRRK2 G2019S Mutation
Knab, F.; Guaitoli, G.; Jarboui, M. A.; von Zweydorf, F.; Isik, F. B.; Klose, F.; Rajkumar, A. P.; Gasser, T.; Gloeckner, C. J.
10.1101/2024.09.20.614055 — neuroscience — Posted on 2024-09-20
1978 Neuronal lipid droplets play a conserved and sex-biased role in maintaining whole-body energy homeostasis
Manceau, R.; Majeur, D.; Cherian, C. M.; Miller, C. J.; Wat, L. W.; Fisher, J. D.; Labarre, A.; Hollman, S.; Prakash, S.; Audet, S.; Chao, C. F.; Depaauw-Holt, L. R.; Rogers, B.; Bosson, A.; Xi, J. J. Y.; Callow, C. A. S.; Yoosefi, N.; Shahraki, N.; Xia, Y. H.; Hui, A.; VanderZwaag, J.; Bouyakdan, K.; Rodaros, D.; Kotchetkov, P.; Daneault, C.; Fallahpour, G.; Tetreault, M.; Tremblay, M.-E.; Ruiz, M.; Lacoste, B.; Parker, A.; Murphy-Royal, C.; Huan, T.; Fulton, S.; Rideout, E.; Alquier, T.
10.1101/2024.09.19.613929 — neuroscience — Posted on 2024-09-20
1979 Arterial spin labelling perfusion MRI analysis for the Human Connectome Project Lifespan Ageing and Development studies
Kirk, T. F.; McConnell, F. A. K.; Toner, J.; Craig, M. S.; Carone, D.; Li, X.; Suzuki, Y.; Coalson, T. S.; Harms, M. P.; Glasser, M. F.; Chappell, M. A.
10.1101/2024.09.19.613907 — neuroscience — Posted on 2024-09-20
1981 T1234: A distortion-matched structural scan solution to misregistration of high resolution fMRI data
Kan, C.; Stirnberg, R.; Montequin, M.; Gulban, O. F.; Morgan, A. T.; Bandettini, P.; Huber, L.
10.1101/2024.09.19.613939 — neuroscience — Posted on 2024-09-20
1985 Patterned wireless transcranial optogenetics generates artificial perception
Wu, M.; Yang, Y.; Zhang, J.; Efimov, A. I.; Vazquez-Guardado, A.; Li, X.; Zhang, K.; Wang, Y.; Gu, J.; Zeng, L.; Liu, J.; Riahi, M.; Yoon, H.; Kim, M.; Zhang, H.; Lee, M.; Kang, J.; Ting, K.; Cheng, S.; Zhang, W.; Banks, A.; Good, C. H.; Cox, J. M.; Pinto, L.; Huang, Y.; Kozorovitskiy, Y.; Rogers, J. A.
10.1101/2024.09.20.613966 — neuroscience — Posted on 2024-09-20
1987 Evidence that Dmrta2 acts as a transcriptional repressor of Pax6 in murine cortical progenitors and identification of a mutation crucial for DNA recognition associated with microcephaly in human
Shen, X.; Anirudhan, J.; Fatima, A.; Szemes, T.; Keruzore, M.; Plant, E.; Sabate San Jose, A.; Kricha, S.; Delhaye, L. P.; Mian, B. A.; Khalid, L. B.; Ali, F.; Zahra, H.; Ali, A.; Toft, M.; Dieu, M.; Van Lint, C.; Achouri, Y.; Renard, P.; Iqbal, Z.; Bellefroid, E. J.
10.1101/2024.09.20.614077 — neuroscience — Posted on 2024-09-20
1991 Increased neuronal expression of the early endosomal adaptor APPL1 leads to endosomal and synaptic dysfunction with cholinergic neurodegeneration
Jiang, Y.; Sachdeva, K.; Goulbourne, C. N.; Berg, M. J.; Peddy, J.; Stavrides, P. H.; Pensalfini, A.; Pawlik, M.; Whyte, L. S.; Basavaraj, B. S.; Shivakumar, S.; Bleiwas, C.; Smiley, J. F.; Mathews, P. M.; Nixon, R. A.
10.1101/2024.09.19.613736 — neuroscience — Posted on 2024-09-20
1993 Decoding Parametric Grip-Force Anticipation from fMRI-Data
Caccialupi, G.; Schmidt, T. T.; Nierhaus, T.; Wesolek, S.; Esmeyer, M. F.; Blankenburg, F.
10.1101/2024.09.19.613884 — neuroscience — Posted on 2024-09-20
1995 Resting-state hyper- and hypo-connectivity in early schizophrenia: which tip of the iceberg should we focus on?
Tomecek, D.; Kolenic, M.; Rehak Buckova, B.; Tintera, J.; Spaniel, F.; Horacek, J.; Hlinka, J.
10.1101/2024.09.20.613853 — neuroscience — Posted on 2024-09-20
2004 scaLR: a low-resource deep neural network-based platform for single cell analysis and biomarker discovery
Jogani, S.; Pol, A. S.; Prajapati, M.; Samal, A.; Bhatia, K.; Parmar, J.; Patel, U.; Shah, F.; Vyas, N.; Gupta, S.
10.1101/2024.09.19.613226 — bioinformatics — Posted on 2024-09-20
2006 Immobilized Nucleoside 2'-Deoxyribosyltransferases from Extremophiles for Nucleoside Biocatalysis
Hernandez Martinez, S. A.; Tang, P.; Parra-Saldivar, R.; Melchor-Martinez, E. M.; Czekster, C. M.
10.1101/2024.09.20.614042 — biochemistry — Posted on 2024-09-20
2008 Optimized Enrichment of Murine Blood-Brain Barrier Vessels with a Critical Focus on Network Hierarchy in Post-Collection Analysis
Abdelazim, H.; Barnes, A.; Stupin, J.; Hasson, R.; Munoz-Ballester, C. C.; Young, K. L.; Robel, S.; Smyth, J. W.; Lamouille, S.; Chappell, J. C.
10.1101/2024.09.19.613898 — neuroscience — Posted on 2024-09-20
2009 Elicitor specific mechanisms of defence priming in oak seedlings against powdery mildew
Sanchez-Lucas, R.; Bosanquet, J. L.; Henderson, J.; Catoni, M.; Pastor, V.; Luna, E.
10.1101/2024.09.20.613659 — plant biology — Posted on 2024-09-20
2010 Innate Immune Receptor NLRX1: Potential Modulator of Glioblastoma Pathophysiology
Meena, D.; Shivakumar, D.; Rajkhowa, s.; Bhattacharya, N.; Solanki, P.; Chhipa, S.; Janu, V.; Garg, M.; Gosal, J. S.; Jha, S.
10.1101/2024.09.19.613932 — cancer biology — Posted on 2024-09-20
2011 The predominant binding mode of Palmatine to DNA
Gentile, M.; Talotta, F.; Tremblay, J. C.; Gonzalez, L.; MONARI, A.
10.1101/2024.09.17.613446 — biophysics — Posted on 2024-09-20
2013 Epigenomic analysis of hepatocellular carcinoma reveals aberrant cis-regulatory changes and dysregulated retrotransposons with prognostic potentials
Cheng, C. C. Y.; Cheung, M. F.; Lee, A. Y.; Wu, Q.; Chow, S. H.-C.; Ang, J. Y. J.; Riquelme Medina, I.; Lo, G.; Wu, H.; Yang, W.; Lai, P. B. S.; Yip, K.; Cheng, A.; Leung, D. C. Y.
10.1101/2024.09.16.613254 — genomics — Posted on 2024-09-20
2014 Saccharomyces Genome Database: Advances in Genome Annotation, Expanded Biochemical Pathways, and Other Key Enhancements
Engel, S. R.; Aleksander, S.; Nash, R. S.; Wong, E. D.; Weng, S.; Miyasato, S. R.; Sherlock, G.; Cherry, J. M.
10.1101/2024.09.16.613348 — genetics — Posted on 2024-09-20
2017 Plants reverse the positive effect of nutrient addition on the drought resistance of soil multifunctionality
Piton, G.; Foulquier, A.; Bernard, L.; Bonin, A.; Pommier, T.; Lavorel, S.; Geremia, R.; Clement, J. C.
10.1101/2024.09.19.613911 — ecology — Posted on 2024-09-20
2018 A proximity ligation screen identifies SNAT2 as a novel target of the MARCH1 E3 ubiquitin ligase
Balthazard, R.; Mitchell, W.; Raymond, M.; Ballestero-VIdal, A.; Roy, D. G.; Palma Zambrano, L. C.; Moulefera, M. A.; Faubert, D.; Pasquin, S.; Gauchat, J.-F.; Thibodeau, J.
10.1101/2024.09.16.613264 — immunology — Posted on 2024-09-20
2019 DNA-PK controls cyclic dinucleotide-associated type I Interferon responses
taffoni, c.; vila, i. k.; jardine, j.; schussler, m.; McKellar, J.; Chemarin, M.; Re, J.; Messaout-Nacer, Y.; El Mansouri, I.; Chrousos, G. P.; Bidere, N.; Majzoub, K.; Vlachakis, D.; Laguette, N.
10.1101/2024.09.17.613246 — immunology — Posted on 2024-09-20
2020 Sca-1 expression depicts pro-inflammatory murine neutrophils under steady state and pathological conditions
Nahiyera, M.; Sinha, S.; Dhankani, P.; Singhal, A.; Singh, A.; Sharma, R. K.; Gond, A.; Gupta, K.; Mitra, K.; LAHIRI, A.; Jagavelu, K.; Filippi, M.-D.; Dikshit, M.; Kumar, S.
10.1101/2024.09.16.613221 — immunology — Posted on 2024-09-20
2023 Altered development and network connectivity in a human neuronal model of 15q11.2 deletion-related neurodevelopmental disorders
Habela, C. W.; Liu, S.; Taga, A.; Dastgheyb, R.; Haughey, N.; Bergles, D. E.; Song, H.; Ming, G.-L.; Maragakis, N. J.
10.1101/2024.09.19.613912 — neuroscience — Posted on 2024-09-20
2024 PTPN11 Mutation Clonal Hierarchy in Acute Myeloid Leukemia
Fobare, S.; Sharpe, C.; Quinn, K.; Bryant, K.; Miles, L. A.; Bowman, R. L.; Cheney, C.; Furby, C.; Long, M.; Fyock, K.; Wronowski, B.; Lerma, J. R.; Mullaney, A.; Mrozek, K.; Nicolet, D.; Sesterhenn, T.; Johnstone, M. E.; Rai, S. N.; Pasare, C.; Zimmermann, N.; Carroll, A. J.; Stone, R. M.; Wang, E. S.; Kolitz, J. E.; Powell, B. L.; Perentesis, J. P.; Eisfeld, A.-K.; Hertlein, E.; Byrd, J. C.
10.1101/2024.09.18.612239 — cancer biology — Posted on 2024-09-20
2025 A Bayesian framework to infer and cluster mutational signatures leveraging prior biological knowledge.
Buscaroli, E.; Haghighi, A. S.; Bergamin, R.; Milite, S.; Garcia, E. N. V.; Tasciotti, A.; Ansuini, A.; Ramazzotti, D.; Calonaci, N.; Caravagna, G.
10.1101/2024.09.16.613266 — cancer biology — Posted on 2024-09-20
2026 Identification of natural Zika virus peptides presented on the surface of paediatric brain tumour cells by HLA classI
Sherwood, M.; Nicholas, B.; Bailey, A.; Mitsugi, T.; Kaid, C.; Okamoto, O. K.; Skipp, P.; Ewing, R. M.
10.1101/2024.09.17.613406 — cancer biology — Posted on 2024-09-20
2028 Multiplexed lifetime imaging of single molecules with a gated single-photon camera
Ronceray, N.; Bennani, S.; Mitsioni, M.; Siegel, N.; Marcaida, M. J.; Bruschini, C.; Charbon, E.; Roy, R.; Dal Peraro, M.; Acuna, G. P.; Radenovic, A.
10.1101/2024.09.17.613468 — biophysics — Posted on 2024-09-20
2029 A high-resolution microscopy system for biological studies of cold-adapted species under physiological conditions
Marty, A.-P. M.; Ward, E. N.; Lamb, J. R.; van Tartwijk, F. W.; Peck, L. S.; Clark, M. S.; Kaminski, C. F.
10.1101/2024.09.17.613460 — biophysics — Posted on 2024-09-20
2031 Network-driven identification of indisulam neo-substrates for targeted protein degradation
Jarnuczak, A. F.; Andres, A.; Yogev, O.; Ashenden, S. K.; Ye, C.; Pachl, F.; Zhang, A.; Cuomo, M. E.; Jin, M.
10.1101/2024.09.16.613231 — bioinformatics — Posted on 2024-09-20
2032 Clustered macrophages cooperate to eliminate tumors via coordinated intrudopodia
Dooling, L. J.; Anlas, A. A.; Tobin, M. P.; Ontko, N. M.; Marchena, T.; Wang, M.; Andrechak, J. C.; Discher, D. E.
10.1101/2024.09.19.613918 — bioengineering — Posted on 2024-09-20
2033 Glucomannan engineering highlights the role of galactosyl modification in fine-tuning cellulose-glucomannan interaction in Arabidopsis cell walls
Yoshimi, Y.; Yu, L.; Cresswell, R.; Guo, X.; Echevarria-Poza, A.; Lyczakowski, J. J.; Dupree, R.; Kotake, T.; Dupree, P.
10.1101/2024.09.19.613614 — bioengineering — Posted on 2024-09-20
2041 Extinction potential from invasive alien species
Philippe-Lesaffre, M.; Arbieu, U.; Bang, A.; Camacho, M.; Cuthbert, R.; Genovesi, P.; Kumschick, S.; Pili, A.; Seebens, H.; Wang, S.; Latombe, G.
10.1101/2024.09.01.610685 — ecology — Posted on 2024-09-20
2042 Gonadotrophs have a dual origin, with most derived from pituitary stem cells during minipuberty.
Sheridan, D.; Chakravarty, P.; Golan, G.; Shiakola, Y.; Olsen, J.; Burnett, E.; Galichet, C.; Mollard, P.; Melamed, P.; Lovell-Badge, R.; Rizzoti, K.
10.1101/2024.09.09.610834 — developmental biology — Posted on 2024-09-20
2043 Investigation of plant virus-like particle formation in bacterial and yeast expression systems
Balke, I.; Resevica, G.; Zeltina, V.; Silamikelis, I.; Liepa, E.; Liepa, R.; Kalnciema, I.; Radovica-Spalvina, I.; Gudra, D.; Pjalkovskis, J.; Freivalds, J.; Kazaks, A.; Zeltins, A.
10.1101/2024.09.20.614045 — molecular biology — Posted on 2024-09-20
2045 Herpes Simplex Virus Assembly and Spread in murine skin after infection from the outside
Richardo, T.; Sodeik, B.; Halle, S.; Buch, A.; Binz, A.; Pohlmann, A.; de le Roi, M.; Baumgartner, W.; Brand, K.; Bauerfeind, R.; Forster, R.; Dohner, K.; lLu, X.
10.1101/2024.09.18.613798 — microbiology — Posted on 2024-09-20
2046 Novel regulator Fpr2 controls immune homeostasis via CCL4-dependent neutrophils
Mei, S.; Zhang, P.; Jiang, Y.; Xu, S.; Yi, J.; Zhang, S.; Wang, Y.; Liu, P.; Liu, H.; Lv, Q.; Huang, W.; Kong, D.; Li, Q.; Ren, Y.; Sun, Z.; Jiang, H.
10.1101/2024.09.13.612885 — immunology — Posted on 2024-09-20
2047 Diphthamide formation in Arabidopsis requires DPH1-interacting DPH2 for light and oxidative stress resistance
Kraemer, U.; Zhang, H.; Janina, N.; Ütkür, K.; Manivannan, T.; Zhang, L.; Wang, L.; Grefen, C.; Schaffrath, R.
10.1101/2024.09.16.613322 — plant biology — Posted on 2024-09-20
2048 Glycosite Mapping and in situ Mass Spectrometry Imaging of MUC2 Glycopeptides via On-slide Digestion with Mucinase StcE
Lowery, S. C.; Tran, I. P.; Grimsley, G.; Stubler, R.; Mahoney, K. E.; Lucas, T. M.; Charkoftaki, G.; Santos-Neto, A.; Varki, N.; Vasiliou, V.; Drake, R. R.; Malaker, S. A.
10.1101/2024.09.16.613285 — cancer biology — Posted on 2024-09-20
2049 Yttrium-90-doped metal-organic frameworks (MOFs) for low-dose rate intratumoral radiotherapy
Qi, X.; Fedotova, A.; Yu, Z.; Polyanskaya, A.; Shen, N.; Egorova, B.; Bagrov, D.; Slastnikova, T.; Rosenkranz, A.; Patriarche, G.; Nevolin, Y.; Permyakova, A.; Fedotov, S.; Lepoitevin, M.; Kalmykov, S.; Serre, C.; Durymanov, M.
10.1101/2024.09.14.613012 — biophysics — Posted on 2024-09-20
2051 Global Genotype by Environment Prediction Competition Reveals That Diverse Modeling Strategies Can Deliver Satisfactory Maize Yield Estimates
Washburn, J. D.; Varela, J. I.; Xavier, A.; Chen, Q.; Ertl, D.; Gage, J. L.; Holland, J. B.; Lima, D. C.; Romay, M. C.; Lopez-Cruz, M.; de los Campos, G.; Barber, W.; Zimmer, C.; Trucillo Silva, I.; Rocha, F.; Rincent, R.; Ali, B.; Hu, H.; Runcie, D. E.; Gusev, K.; Slabodkin, A.; Bax, P.; Aubert, J.; Gangloff, H.; Mary-Huard, T.; Vanrenterghem, T.; Quesada-Traver, C.; Yates, S.; Ariza-Suarez, D.; Ulrich, A.; Wyler, M.; Kick, D. R.; Bellis, E. S.; Causey, J. L.; Soriano Chavez, E.; Wang, Y.; Piyush, V.; Fernando, G. D.; Hu, R. K.; Kumar, R.; Timon, A. J.; Venkatesh, R.; Segura Aba, K.; Chen, H.
10.1101/2024.09.13.612969 — genetics — Posted on 2024-09-20
2052 The digestion time for salmon louse (Lepeoptheirus salmonis) in lumpfish (Cyclopterus lumpus) in relation to freshness, developmental stage, and temperature
Eliasen, K.; Ostero, S. L.; Johannesen, T. T.; Patursson, E. J.; Jacobsen, A.; Mortensen, A. M.; Nolsoe, M.; Johannesen, A.
10.1101/2024.09.14.613060 — ecology — Posted on 2024-09-20
2053 Post-transcriptional regulation of IFI16 promotes inflammatory endothelial pathophenotypes observed in pulmonary arterial hypertension
Rao, R. J.; Yang, J.; Jiang, S.; El Khoury, W.; Hafeez, N.; Okawa, S.; Tai, Y. Y.; Tang, Y.; Al Aaraj, Y.; Sembrat, J.; Chan, S. Y.
10.1101/2024.09.19.613988 — cell biology — Posted on 2024-09-20
2055 Structural basis of interdomain communication in PPARγ
Mosure, S. A.; Munoz-Tello, P.; Kuo, K.-T.; MacTavish, B.; Yu, X.; Scholl, D.; Williams, C. C.; Strutzenberg, T. S.; Li, J.; Bass, J.; Brust, R.; Kalkhoven, E.; Deniz, A. A.; Griffin, P. R.; Kojetin, D.
10.1101/2022.07.13.499031 — biophysics — Posted on 2024-09-20
2057 Manufacturing-Aware Generative Model Architectures Enable Biological Sequence Design and Synthesis at Petascale
Weinstein, E. N.; Gollub, M. G.; Slabodkin, A.; Gardner, C. L.; Dobbs, K.; Cui, X.-B.; Amin, A. N.; Church, G. M.; Wood, E. B.
10.1101/2024.09.13.612900 — bioengineering — Posted on 2024-09-20
2058 Evaluating Methods for the Prediction of Cell Type-Specific Enhancers in the Mammalian Cortex
Johansen, N. J.; Kempynck, N.; Zemke, N. R.; Somasundaram, S.; Winter, S. D.; Hooper, M.; Dwivedi, D.; Lohia, R.; Wehbe, F.; Li, B.; Abaffyova, D.; Armand, E. J.; Man, J. D.; Eksi, E. C.; Hecker, N.; Hulselmans, G.; Konstantakos, V.; Mauduit, D.; Mich, J. K.; Partel, G.; Daigle, T. L.; Levi, B. P.; Zhang, K.; Tanaka, Y.; Gillis, J.; Ting, J. T.; Ben-Simon, Y.; Miller, J.; Ecker, J. R.; Ren, B.; Aerts, S.; Lein, E. S.; Tasic, B.; Bakken, T. E.
10.1101/2024.08.21.609075 — genomics — Posted on 2024-09-20
2059 Comparative single cell analysis reveals complex patterns of cell type and cell signaling innovations at the fetal-maternal interface
Stadtmauer, D. J.; Basanta, S.; Maziarz, J. D.; Cole, A. G.; Dagdas, G.; Smith, G. R.; van Breukelen, F.; Pavlicev, M.; Wagner, G. P.
10.1101/2024.05.01.591945 — evolutionary biology — Posted on 2024-09-20
2063 AusAMF: database of arbuscular mycorrhizal fungal communities in Australia
Frew, A.; Powell, J.; Heuck, M. K.; Albornoz, F.; Birnbaum, C.; Dearnaley, J.; Egidi, E.; Finn, L.; Kath, J.; Koorem, K.; Oja, J.; Opik, M.; Vahter, T.; Vasar, M.; Watts-Williams, S.; Zheng, Y.; Aguilar-Trigueros, C. A.
10.1101/2024.09.16.612857 — ecology — Posted on 2024-09-20
2067 Scalable Hypothalamic Arcuate Neuron Differentiation from Human Pluripotent Stem Cells Suitable for Modeling Metabolic and Reproductive Disorders
Jovanovic, V. M.; Narisu, N.; Bonnycastle, L. L.; Tharakan, R.; Mesch, K. T.; Glover, H. J.; Yan, T.; Sinha, N.; Sen, C.; Castellano, D.; Yang, S.; Blivis, D.; Ryu, S.; Bennett, D. F.; Rosales-Soto, G.; Inman, J.; Ormanoglu, P.; LeClair, C. A.; Xia, M.; Schneider, M.; Hernandez-Ochoa, E. O.; Erdos, M. R.; Simeonov, A.; Chen, S.; Collins, F. S.; Doege, C. A.; Tristan, C. A.
10.1101/2024.06.27.601062 — developmental biology — Posted on 2024-09-20
2068 Disulfide-mediated tetramerization of TRAP1 fosters its antioxidant and pro-neoplastic activities.
Faienza, F.; Laquatra, C.; Castelli, M.; Rizza, S.; Guarra, F.; Roshani Dashtmian, A.; Giglio, P.; Pecorari, C.; Ferrone, L.; Moroni, E.; Pacello, F.; Battistoni, A.; Colombo, G.; Rasola, A.; Filomeni, G.
10.1101/2024.09.19.613878 — cell biology — Posted on 2024-09-20
2069 UGGT1-mediated reglucosylation of N-glycan competes with ER-associated degradation of unstable and misfolded glycoproteins
Ninagawa, S.; Matsuo, M.; Ying, D.; Oshita, S.; Aso, S.; Matsushita, K.; Taniguchi, M.; Fueki, A.; Yamashiro, M.; Sugasawa, K.; Saito, S.; Imami, K.; Kizuka, Y.; Sakuma, T.; Yamamoto, T.; Yagi, H.; Kato, K.; Mori, K.
10.1101/2023.10.18.562958 — cell biology — Posted on 2024-09-20
2070 Visualizing nuclear pore complex plasticity with Pan-Expansion Microscopy
Morgan, K. J.; Carley, E.; Coyne, A. N.; Rothstein, J. D.; Lusk, C. P.; King, M. C.
10.1101/2024.09.18.613744 — cell biology — Posted on 2024-09-20
2071 Redirecting full-length FLT1 expression towards its soluble isoform promotes postischemic angiogenesis
Bundalo, M.; Vorlova, S.; Ulrich, J.; Barbieri, R.; Richter, L.; Hoena, L.; Egg, M.; Bock, J.; Schaefer, S.; Amezaga Sole, N.; Rosa, A.; Rizzo, G.; Cochain, C.; Kastenmueller, W.; Henke, E.; Skryabin, B. V.; Rozhdestvensky, T. S.; Wildgruber, M.; Lorenz, K.; Kuhn, M.; Zernecke, A.
10.1101/2024.09.19.613989 — cell biology — Posted on 2024-09-20
2074 Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi-Goutieres Syndrome neuropathology
Nemec, K. M.; Uy, G.; Chaluvadi, V. S.; Purnell, F. S.; Elfayoumi, B.; O'Brien, C. A.; Aisenberg, W. H.; Lombroso, S. I.; Guo, X.; Blank, N.; Oon, C. H.; Yaqoob, F.; Temsamrit, B.; Rawat, P.; Thaiss, C. A.; Wang, Q.; Bennett, M. L.; Bennett, F. C.
10.1101/2024.09.18.613629 — neuroscience — Posted on 2024-09-20
2076 Single-nucleus RNA sequencing reveals enduring signatures of acute stress and chronic exercise in striatal microglia
Connolly, M. G.; Johnson, Z. V.; Chu, L.; Johnson, N. D.; Buhr, T. J.; McNeill, E. M.; Clark, P. J.; Rhodes, J. S.
10.1101/2024.06.24.600469 — neuroscience — Posted on 2024-09-20
2078 Muscle spindles provide flexible sensory feedback for movement sequences
Olson, W. P.; Chokshi, V. B.; Kim, J. J.; Cowan, N.; O'Connor, D. H.
10.1101/2024.09.13.612899 — neuroscience — Posted on 2024-09-20
2079 An instantaneous voice synthesis neuroprosthesis
Wairagkar, M.; Card, N. S.; Singer-Clark, T.; Hou, X.; Iacobacci, C.; Hochberg, L. R.; Brandman, D. M.; Stavisky, S. D.
10.1101/2024.08.14.607690 — neuroscience — Posted on 2024-09-20
2080 Drug-Induced p53 Activation Limits Pancreatic Cancer Initiation
Twardowski, J. J.; Heist, T. I.; Soares, Z. G.; Berry, E. S.; Ruffolo, L. I.; Proschel, C.; Mello, S. S.
10.1101/2024.05.29.595146 — cancer biology — Posted on 2024-09-20
2082 metagWGS, a comprehensive workflow to analyze metagenomic data using Illumina or PacBio HiFi reads
Mainguy, J.; Vienne, M.; Fourquet, J.; Darbot, V.; Noirot, C.; Castinel, A.; Combes, S.; Gaspin, C.; Milan, D.; Donnadieu, C.; Iampietro, C.; Bouchez, O.; Pascal, G.; Hoede, C.
10.1101/2024.09.13.612854 — bioinformatics — Posted on 2024-09-20
2083 The resting and ligand-bound states of the membrane-embedded human T-cell receptor-CD3 complex
Notti, R. Q.; Yi, F.; Heissel, S.; Bush, M. W.; Molvi, Z.; Das, P.; Molina, H.; Klebanoff, C. A.; Walz, T.
10.1101/2023.08.22.554360 — biochemistry — Posted on 2024-09-20
2085 Extrachromosomal DNA Associates with Nuclear Condensates and Reorganizes Chromatin Structures to Enhance Oncogenic Transcription
Taghbalout, A.; Tung, C.-H.; Clow, P. A.; Wang, P.; Tjong, H.; Wong, C. H.; Mao, D. D.; Maurya, R.; Huang, M.-F.; Ngan, C. Y.; Kim, A. H.; Wei, C.-L.
10.1101/2024.09.17.613488 — genomics — Posted on 2024-09-20
2087 What are the best practices for curating eDNA custom barcode reference libraries? A case study using Australian subterranean fauna.
Guzik, M.; Stringer, D.; Thornhill, J.; Coates, P. J.; van der Heyde, M.; Hillyer, M.; White, N. E.; Sacco, M.; Beasley-Hall, P. G.; Humphreys, W. F.; Harvey, M. S.; Huey, J. A.; Wilson, N. G.; Alexander, J.; Humphreys, G.; King, R. A.; Cooper, S. J. B.; Pinder, A.; Perina, G.; Nevill, P.; Austin, A.
10.1101/2024.09.18.611555 — evolutionary biology — Posted on 2024-09-20
2089 Inward transport of organelles drives outward migration of the spindle during C. elegans meiosis
Peraza, A. A.; Li, W.; Lele, A.; Lazureanu, D. G.; Hampton, M. F.; Do, R. M.; Lafrades, M. C.; Barajas, M. G.; Batres, A. A.; McNally, F. J.
10.1101/2024.09.19.613972 — cell biology — Posted on 2024-09-20
2091 InTraSeq: A Multimodal Assay that Uncovers New Single-Cell Biology and Regulatory Mechanisms
Ariss, M. M.; Huang, L.; Ding, X.; Sheth, S.; Levy, T.; Fisher, J.; Loebelenz, J.; Arlotta, K.; Dixon, K.; Polakiewicz, R.; Kuchroo, V. K.; Beausoleil, S. A.
10.1101/2024.09.19.613947 — cell biology — Posted on 2024-09-20
2093 Functional connectivity is dominated by aperiodic, rather than oscillatory, coupling
Monchy, N.; Duprez, J.; Houvenaghel, J.-F.; Legros, A.; Voytek, B.; Modolo, J.
10.1101/2024.09.18.613682 — neuroscience — Posted on 2024-09-20
2094 SoyOD: An Integrated Soybean Multi-omics Database for Mining Genes and Biological Research
Li, J.; Ni, Q.; He, G.; Huang, J.; Chao, H.; Li, S.; Chen, M.; Hu, G.; Whelan, J.; Shou, H.
10.1101/2024.09.19.613982 — plant biology — Posted on 2024-09-20
2095 Pangenome-Informed Language Models for Privacy-Preserving Synthetic Genome Sequence Generation
Huang, P.; Charton, F.; Schmelzle, J.-N. M.; Darnell, S. S.; Prins, P.; Garrison, E.; Suh, G. E.
10.1101/2024.09.18.612131 — bioinformatics — Posted on 2024-09-20
2100 One Health in Eastern Africa: No barriers for ESBL producing E. coli transmission or independent antimicrobial resistance gene flow across ecological compartments
Musicha, P.; Beale, M. A.; Cocker, D.; Oruru, F. A.; Zuza, A.; Salifu, C.; Katende, G.; Nanono, S.; Chidziwisano, K.; Mugisha, L.; Kajumbula, H.; Musoke, D.; Morse, T.; Jacob, S.; Feasey, N. A.; Thomson, N.
10.1101/2024.09.18.613694 — genomics — Posted on 2024-09-19
2103 GDNF family receptor alpha-like (GFRAL) expression is restricted to the caudal brainstem
Hes, C.; Gui, L.; Bay, A.; Alvarez, F.; Katz, P.; Paul, T.; Bozadjieva-Kramer, N.; Seeley, R. J.; Piccirillo, C. A.; Sabatini, P. V.
10.1101/2024.09.19.613956 — molecular biology — Posted on 2024-09-19
2106 Redefining the Limits of Functional Continuity in the Early Evolution of P-Loop NTPases
Demkiv, A. O.; Toledo-Patino, S.; Medina-Carmona, E.; Berg, A.; Pinto, G. P.; Parracino, A.; Sanchez-Ruiz, J. M.; Hengge, A. C.; Laurino, P.; Longo, L. M.; Kamerlin, S. C. L.
10.1101/2024.09.17.613540 — biophysics — Posted on 2024-09-19
2107 Highly accurate assembly polishing with DeepPolisher
Mastoras, M.; Asri, M.; Brambrink, L.; Hebbar, P.; Kolesnikov, A.; Cook, D. E.; Nattestad, M.; Lucas, J.; Won, T. S.; Chang, P.-C.; Carroll, A.; Paten, B.; Shafin, K.
10.1101/2024.09.17.613505 — bioinformatics — Posted on 2024-09-19
2112 The human ribosome modulates multidomain protein biogenesis by delaying cotranslational domain docking
Pellowe, G. A.; Voisin, T. B.; Karpauskaite, L.; Maslen, S. L.; Roeselova, A.; Skehel, M.; Roustan, C.; George, R.; Nans, A.; Kjaer, S.; Taylor, I. A.; Balchin, D.
10.1101/2024.09.19.613857 — biochemistry — Posted on 2024-09-19
2113 Molecular consequences of SCA5 mutations in the spectrin-repeat domains of beta-III-spectrin
Denha, S.; DeLaet, N.; Abukamil, A.; Alexopoulos, A.; Keller, A.; Atang, A.; Avery, A.
10.1101/2024.09.17.613313 — biochemistry — Posted on 2024-09-19
2115 Conformational flexibility is a critical factor in designing broad-spectrum human norovirus protease inhibitors
Pham, S. H.; Zhao, B.; Neetu, N.; Sankaran, B.; Patil, K.; Ramani, S.; Song, Y.; Estes, M. K.; Palzkill, T.; Prasad, B. V. V.
10.1101/2024.09.16.613336 — biochemistry — Posted on 2024-09-19
2116 Untargeted and Semi-Targeted Metabolomics Approach for Profiling Small Intestinal and Fecal Metabolome Using High-Resolution Mass Spectrometry
TRONEL, a.; Roger-Margueritat, m.; Plazy, C.; Cunin, v.; Mohanty, I.; Dorrestein, P. C.; Soranzo, T.; LE GOUELLEC, a.
10.1101/2024.09.16.613180 — biochemistry — Posted on 2024-09-19
2120 Synergistic and antagonistic activities of IRF8 and FOS enhancer pairs during an immune cell fate switch
Klonizakis, A.; Alcoverro-Bertran, M.; Masso, P.; Thomas, J.; de Andres-Aguayo, L.; Wei, X.; Varamogianni-Mamatsi, V.; Nikolaou, C.; Graf, T.
10.1101/2024.09.17.613195 — genomics — Posted on 2024-09-19
2121 A virus associated with the zoonotic pathogen Plasmodium knowlesi causing human malaria is a member of a diverse and unclassified viral taxon
Petrone, M. E.; Charon, J.; Grigg, M. J.; William, T.; Rajahram, G. S.; Westaway, J.; Piera, K. A.; Shi, M.; Anstey, N. M.; Holmes, E. C.
10.1101/2024.09.18.613759 — evolutionary biology — Posted on 2024-09-19
2125 Maf-family bZIP transcription factor NRL interacts with RNA-binding proteins and R-loops in retinal photoreceptors
Corso Diaz, X.; Liang, X.; Preston, K.; Tegshee, B.; English, M. A.; Nellissery, J.; Yadav, S. P.; Marchal, C.; Swaroop, A.
10.1101/2024.09.19.613899 — molecular biology — Posted on 2024-09-19
2126 SARS-CoV-2 Survival on Skin and its Transfer from Contaminated Surfaces
Pitol Garcia, A. K.; Venkatesan, S.; Richards, S.; Hoptroff, M.; Majumdar, A.; Hughes, G.
10.1101/2024.09.18.613660 — microbiology — Posted on 2024-09-19
2127 Peripheral opioid receptor antagonism alleviates fentanyl-induced cardiorespiratory depression and is devoid of aversive effects
Ruyle, B.; Masud, S.; Kesaraju, R.; Tahirkheli, M.; Modh, J.; Lopera, S. A.; Lintz, T.; Higginbotham, J. A.; Massaly, N.; Moron-Concepcion, J.
10.1101/2024.09.16.613257 — physiology — Posted on 2024-09-19
2128 Reduced Hydrogen Sulfide Bioavailability Contributes to Cardiometabolic Heart Failure with Preserved Ejection Fraction
Doiron, J.; Elbatreek, M.; Xia, H.; Yu, X.; Tang, W. H. W.; LaPenna, K.; Sharp, T.; Goodchild, T.; Xian, M.; Xu, S.; Quiriarte, H.; Allerton, T.; Zagouras, A.; Wilcox, J.; Shah, S.; Pfeilschifter, J.; Beck, K.-F.; Li, Z.; Lefer, D.
10.1101/2024.09.16.613349 — pharmacology and toxicology — Posted on 2024-09-19
2129 A Strategic Blend of Stabilizing Polymers to Control Particle Surface Charge for Enhanced Mucus Transport and Cell Binding
Stevens, C. A.; Sevarika, B.; Wilson, B. K.; Wang, C.-M.; Carcamo-Oyarce, G.; Degen, G.; Kassis, T.; Lehr, C. M.; Carrier, R.; Ribbeck, K.; Prud'homme, R. K.
10.1101/2024.09.17.613453 — biophysics — Posted on 2024-09-19
2131 Robust CRISPR/dCas13 RNA blockers specifically perturb miRNA-target interactions and rescue type 1 myotonic dystrophy pathology
Hanifi, M.; Ates-Kalkan, P. S.; Wen, W. X.; Fischer, M.; Kroesen, A.; Yu, Z.; Wood, M.; Thongjuea, S.; Mead, A.; Fulga, T. A.; Rinaldi, C.; Sauka-Spengler, T.
10.1101/2024.09.16.612263 — bioengineering — Posted on 2024-09-19
2133 An integrated view of the structure and function of the human 4D nucleome
The 4D Nucleome Consortium, ; Dekker, J.; Oksuz, B. A.; Zhang, Y.; Wang, Y.; Minsk, M. K.; Kuang, S.; Yang, L.; Gibcus, J. H.; Krietenstein, N.; Rando, O.; Xu, J.; Janssens, D. H.; Henikoff, S.; Kukalev, A.; Willemin, A.; Winick-Ng, W.; Kempfer, R.; Pombo, A.; Yu, M.; Kumar, P.; Zhang, L.; Belmont, A. S.; Sasaki, T.; van Schaik, T.; Brueckner, L.; Peric-Hupkes, D.; van Steensel, B.; Wang, P.; Chai, H.; Kim, M.; Ruan, Y.; Zhang, R.; Quinodoz, S. A.; Bhat, P.; Guttman, M.; Zhao, W.; Chien, S.; Liu, Y.; Venev, S. V.; Plewczynski, D.; Irastorza Azcarate, I.; Szabo, D.; Thieme, C. J.; Szczepinska,
10.1101/2024.09.17.613111 — genomics — Posted on 2024-09-19
2134 Chromatin folding motifs define the basic grammar of TAD architecture in single alleles
Messina, O.; Fiche, J.-B.; Elkhoury Youhanna, C.; Ganesh, G.; Kemkem, Y.; Mesnager, A.; Akerman, I.; Hodson, D.; Schaeffer, M.; Nollmann, M.
10.1101/2024.09.18.613689 — genomics — Posted on 2024-09-19
2137 Muscle fiber proteomics reveals sex- and fiber type-specific adaptations to resistance training
Moesgaard, L.; Moreno-Justicia, R.; Schmalbruch, J.; Jessen, S.; Stocks, B.; Bangsbo, J.; Deshmukh, A. S.; Hostrup, M.
10.1101/2024.09.16.612737 — physiology — Posted on 2024-09-19
2139 Deep Video Analysis for Bacteria Genotype Prediction
Dabouei, A.; Mishra, I.; Kapur, K.; Cao, C.; A. Bridges, A.; Xu, M.
10.1101/2024.09.16.613253 — bioinformatics — Posted on 2024-09-19
2140 Benchmarking coarse-grained simulation methods for investigation of transport tunnels in enzymes
Mandal, N.; Stevens, J. A.; Poma, A. B.; Surpeta, B.; Sequeiros-Borja, C.; Thirunavukarasu, A. S.; Marrink, S.-J.; Brezovsky, J.
10.1101/2024.09.16.613244 — bioinformatics — Posted on 2024-09-19
2141 ArchMap: A web-based platform for reference-based analysis of single-cell datasets
Lotfollahi, M.; Bright, C.; Skorobogat, R.; Dehkordi, M.; George, X.; Richter, S.; Topalova, A.; Luecken, M. D.; Theis, F. J.
10.1101/2024.09.19.613883 — bioinformatics — Posted on 2024-09-19
2144 Variant scoring performance across selection regimes depends on variant-to-gene and gene-to-disease components
Finucane, H. K.; Parsa, S.; Guez, J.; Kanai, M.; Satterstrom, F. K.; Nkambule, L. L.; Daly, M. J.; Seed, C.; Karczewski, K. J.
10.1101/2024.09.17.613327 — bioinformatics — Posted on 2024-09-19
2147 A within-host infection model to explore tolerance andresistance
Duneau, D.; Pierre, L.; Christine, L.; Parthuisot, N.; Faucher, C.; Jin, X.; Buchon, N.; Ferdy, J.-B.
10.1101/2021.10.19.464998 — evolutionary biology — Posted on 2024-09-19
2148 A non-canonical planar cell polarity pathway triggered by light
Housset, M.; Filion, D.; Cortes, N.; Vali, H.; Mandato, C.; Casanova, C.; Cayouette, M.
10.1101/2021.04.21.440771 — cell biology — Posted on 2024-09-19
2149 Novel porcine model reveals two distinct LGR5 cell types during lung development and homeostasis
Polkoff, K.; Lampe, R.; Gupta, N. K.; Murphy, Y.; Chung, J.; Carter, A.; Simon, J. M.; Moatti, A.; Kadur Lakshminarasimha Murthy, P.; Gleason, K.; Edwards, L.; Greenbaum, A.; Tata, A.; Tata, P. R.; Piedrahita, J. A.
10.1101/2022.12.09.516617 — cell biology — Posted on 2024-09-19
2150 Linked regulation of genome integrity and senescence-associated inflammation by p53
Miller, K. N.; Li, B.; Pierce-Hoffman, H. R.; Patel, S.; Lei, X.; Rajesh, A.; Teneche, M. G.; Havas, A. P.; Gandhi, A.; Cano Macip, C.; Lyu, J.; Victorelli, S. G.; Woo, S.-H.; Lagnado, A. B.; LaPorta, M. A.; Liu, T.; Dasgupta, N.; Li, S.; Davis, A.; Korotkov, A.; Hultenius, E.; Gao, Z.; Altman, Y.; Porritt, R. A.; Garcia, G.; Mogler, C.; Seluanov, A.; Gorbunova, V.; Kaech, S. M.; Tian, X.; Dou, Z.; Chen, C.; Passos, J. F.; Adams, P. D.
10.1101/2023.11.20.567963 — cell biology — Posted on 2024-09-19
2151 An unusual trafficking domain in MSRP6 defines a complex needed for Maurer's clefts anchoring and maintenance in P. falciparum infected red blood cells
Blancke Soares, A.; Staecker, J.; Schwald, S.; Hoijmakers, W. A. M.; Metwally, N. G.; Cronshagen, J.; Schoeler, H.; Flemming, S.; Hoehn, K.; Froehlke, U.; Mesen-Ramirez, P.; Bergmann, B.; Khosh-Naucke, M.; Bruchhaus, I.; Bartfai, R.; Spielmann, T.
10.1101/2021.12.03.471078 — microbiology — Posted on 2024-09-19
2152 Elucidating early intestinal stem cell response to bacterial infection
Lebon, S.; Davidzohn, N.; Menachem, A. H.; Katz, A.; Wigoda, N.; Rotkopf, R.; Dadosh, T.; Levin-Zaidman, S.; Dezorella, N.; Blumberger, N.; Hoffman, D.; Hofree, M.; Biton, M.
10.1101/2024.09.15.613128 — immunology — Posted on 2024-09-19
2155 Social odors drive hippocampal CA2 place cell responses to social stimuli
Robson, E.; Donahue, M. M.; Mably, A. J.; Demetrovich, P. G.; Hewitt, L. T.; Colgin, L. L.
10.1101/2024.07.16.603738 — neuroscience — Posted on 2024-09-19
2156 Cognitive effort increases the intensity of rewards
Wahab, M.; Mead, N.; Desmercieres, S.; Lardeux, V.; Dugast, E.; Baumeister, R. F.; Solinas, M.
10.1101/2023.08.24.554617 — neuroscience — Posted on 2024-09-19
2158 Human birth tissue products as a non-opioid medicine to inhibit post-surgical pain
Zhang, C.; Huang, Q.; Ford, N. C.; Limjunyawong, N.; Lin, Q.; Yang, F.; Cui, X.; Uniyal, A.; Liu, J.; Mahabole, M.; He, H.; Wang, X.; Duff, I.; Wang, Y.; Wan, J.; Zhu, G.; Raja, S. N.; Jia, H.; Yang, D.; Dong, X.; Cao, X.; Tseng, S.; He, S.; Guan, Y.
10.1101/2024.05.19.594874 — neuroscience — Posted on 2024-09-19
2160 Metabolic modeling reveals a multi-level deregulation of host-microbiome metabolic networks in IBD
Taubenheim, J.; Kadibalban, A. S.; Zimmermann, J.; Taubenheim, C.; Tran, F.; Rosenstiel, P.; Aden, K.; Kaleta, C.
10.1101/2024.09.16.613185 — systems biology — Posted on 2024-09-19
2161 Successful stimulation of myocardial ganglionic plexuses by TAU 20 in the absence of cardiac damage
Li, S.; Kay, J. A.; Agha-Jaffar, D.; S Y Gao, C.; Perkins, J.; Koustsoftidis, S.; Mic, D. E.; Cantwell, C. D.; Wang, L.; Kanagaratnam, P.; Chowdhury, R. A.
10.1101/2024.09.16.613202 — physiology — Posted on 2024-09-19
2162 Testicular sex cord stromal tumors in mice with constitutive activation of PI3K and loss of Pten
Dinevska, M.; Mcaloney, L.; Widodo, S. S.; Filiz, G.; Anderson, J.; Dworkin, S.; Windley, S.; Wilhelm, D.; Mantamadiotis, T.
10.1101/2024.09.16.613175 — cancer biology — Posted on 2024-09-19
2163 DNA polymerase theta-mediated DNA repair is a functional dependency and therapeutic vulnerability in DNMT3A deficient leukemia cells
Le, B. V.; Vekariya, U.; Toma, M. M.; Nieborowska-Skorska, M.; Caron, M.-C.; Gozdecka, M.; Haydar, Z.; Walsh, M.; Ghosh, J.; Vaughan-Williams, E.; Podszywalow-Bartnicka, P.; Kukuyan, A.-M.; Ziolkowska, S.; Hadzijusufovic, E.; Chandramouly, G.; Piwocka, K.; Pomerantz, R.; Vassiliou, G. S.; Huntly, B. J.; Valent, P.; Bellacosa, A.; Masson, J.-Y.; Gupta, G. P.; Challen, G. A.; Skorski, T.
10.1101/2024.09.15.613155 — cancer biology — Posted on 2024-09-19
2164 Aquaporin-4 expression levels and mis-localization are inversely linked to peritumoral edema in gliomas of varying aggressiveness
Valente, O.; Abbrescia, P.; Signorile, G.; Messina, R.; de Gennaro, L.; Bozzi, M. T.; Ingravallo, G.; D'amati, A.; Zimatore, D. S.; Palazzo, C.; Nicchia, G. P.; Frigeri, A.; Signorelli, F.
10.1101/2024.09.15.613106 — cancer biology — Posted on 2024-09-19
2165 SIRPalpha+ PD-L1+ bone marrow macrophages aid AML growth by modulating T cell function
Birch, F.; Gonzalez-Anton, S.; Haltalli, M. L. R.; Chakravarty, P.; Bruno, F.; Georgiou, C.; Mai, C.; Todd, Y.; Payne, E.; Blum, S.; Pospori, C.; Arber, C.; Burt, R.; Tissot, F. S.; Celso, C. L.
10.1101/2024.09.15.613123 — cancer biology — Posted on 2024-09-19
2166 Real-space heterogeneous reconstruction, refinement, and disentanglement of CryoEM conformational states with HetSIREN
Herreros, D.; Mata, C. P.; Noddings, C.; Irene, D.; Krieger, J. M.; Agard, D.; Tsai, M.-D.; Sorzano, C. O. S.; Carazo, J. M.
10.1101/2024.09.16.613176 — bioinformatics — Posted on 2024-09-19
2171 Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold-standard
Lin, Y.-Y.; Breuer, K.; Weichenhan, D.; Lafrenz, P.; Wilk, A.; Chepeleva, M.; Muecke, O.; Schoenung, M.; Petermann, F.; Kensche, P.; Weiser, L.; Thommen, F.; Giacomelli, G.; Nordstroem, K.; Gonzales-Avalos, E.; Merkel, A.; Kretzmer, H.; Fischer, J.; Kraemer, S.; Iskar, M.; Wolf, S.; Buchhalter, I.; Esteller, M.; Lawerenz, C.; Twardziok, S.; Zapatka, M.; Hovestadt, V.; Schlesner, M.; Schulz, M.; Hoffman, S.; Gerhauser, C.; Walter, J.; Hartmann, M.; Lipka, D.; Assenov, Y.; Bock, C.; Plass, C.; Toth, R.; Lutsik, P.
10.1101/2024.09.16.609142 — bioinformatics — Posted on 2024-09-19
2173 Filter bank common spatial pattern and envelope-based features in multimodal EEG-fTCD brain-computer interfaces
Khalaf, A.; Essam, A.-A.; Ibrahim, A.; Zanqour, A.; El-Saqa, M.; Mohamed, S.; Anwar, A.; Eldeib, A.; Akcakaya, M.
10.1101/2024.09.15.613144 — bioengineering — Posted on 2024-09-19
2174 Antimicrobial Potential and Characterization of Silver Nanoparticles Synthesized from Ocimum Sanctum Extract
Sulaiman, M.; Sharma, R.; Shehu Sulaiman, A.; Lawan Abubakar, A.; Abdulmumin Muhammad, M.; Musa Shuaibu, A.; Aliyu, M.; Tasiu Mustapha, I.; Tiwari, R.
10.1101/2024.09.19.613829 — biochemistry — Posted on 2024-09-19
2175 Bisulphite sequencing in the presence of cytosine-conversion errors
Ellis, T. J.; Nizhynska, V.; Pisupati, R.; Molla-Morales, A.; Nordborg, M.
10.1101/2024.09.16.613193 — genomics — Posted on 2024-09-19
2177 Sex-, development-, and nutrition-dependent expression of a major age-at-maturity gene in Atlantic salmon
Asheim, E. R.; Debes, P.; House, A.; Liljestrom, P.; Ruokolainen, A.; Frapin, M.; Donner, I.; Erkinaro, J.; Verta, J.-P.; Primmer, C. R.
10.1101/2024.09.15.613130 — genetics — Posted on 2024-09-19
2181 Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies
Stoddard, E. G.; Fang, L.; Zhong, Y.; Potter, Z. E.; Brush, D. S.; Simon, J. J.; Golkowski, M.; Maly, D. J.
10.1101/2024.09.18.613772 — cell biology — Posted on 2024-09-19
2184 Altered markers of brain metabolism and excitability are associated with executive functioning in young children exposed to alcohol in utero
Perdue, M. V.; Ghasoub, M.; Long, M.; DeMayo, M. M.; Bell, T. K.; McMorris, C. A.; Dewey, D.; Gibbard, W. B.; Tortorelli, C.; Harris, A. D.; Lebel, C.
10.1101/2024.05.06.592786 — neuroscience — Posted on 2024-09-19
2185 Evaluating plant growth-defence trade-offs by modelling the interaction between primary and secondary metabolism
Zrimec, J.; Correa, S.; zagorscak, m.; Petek, M.; Bleker, C.; Stare, K.; Schuy, C.; Sonnewald, S.; Gruden, K.; Nikoloski, Z.
10.1101/2024.09.15.613124 — systems biology — Posted on 2024-09-19
2186 Metabolic growth coupling strategies for in vivo enzyme selection systems
Alter, T. B.; Pieters, P. A.; Lloyd, C. J.; Feist, A. M.; Ozdemir, E.; Palsson, B. O.; Zielinski, D. C.
10.1101/2024.09.16.613188 — systems biology — Posted on 2024-09-19
2189 Multidirectional effect of low-intensity electrical myostimulation on gene expression and phenotype in thigh and calf muscles after one week of disuse
Borzykh, A. A.; Zhedyaev, R. Y.; Ponomarev, I. I.; Vepkhvadze, T. F.; Zgoda, V. G.; Orlova, M. A.; Vavilov, N. E.; Lednev, E. M.; Sharlo, K. A.; Babkova, A. R.; Makhnovskii, P. A.; Shenkman, B. S.; Rukavishnikov, I. V.; Orlov, O. I.; Tomilovskaya, E. S.; Popov, D. V.
10.1101/2024.09.18.613609 — physiology — Posted on 2024-09-19
2190 Melanocortin-4 receptor antagonist TCMCB07 alleviates chemotherapy-induced anorexia and weight loss
Zhu, X.; Potterfield, R.; Gruber, K. A.; Zhang, E.; Newton, S.; Norgard, M. A.; Levasseur, P. R.; Bai, P.; Chen, X.; Gu, Q.; Grossberg, A.; Marks, D. L.
10.1101/2024.09.14.613069 — cancer biology — Posted on 2024-09-19
2191 Molecular Magnetic Resonance Imaging of Dysregulated Zinc Secretion Detects Early Pancreatic Ductal Adenocarcinoma Lesions and Response to KRASG12D Inhibitor Treatment
Jordan, V. C.; Sojoodi, M.; Moloudi, F.; Pagan, P. G.; Jin, M.; Pantazopoulos, P.; French, E.; Weigand-Whittier, J.; Rotile, N.; Tavallai, M.; Hallin, J.; Ramsay, I.; Gale, E. M.; Barrett, S.; Bardeesy, N.; Qadan, M.; Tanabe, K.; Caravan, P.
10.1101/2024.09.15.613145 — cancer biology — Posted on 2024-09-19
2192 A STAG2-PAXIP1/PAGR1 axis suppresses lung tumorigenesis
Ashkin, E. L.; Tang, Y. J.; Xu, H.; Hung, K. L.; Belk, J.; Cai, H.; Lopez, S. S.; Dolcen, D. N.; Hebert, J. D.; Li, R.; Ruiz, P. A.; Keal, T.; Andrejka, L.; Chang, H. Y.; Petrov, D. A.; Dixon, J. R.; Xu, Z.; Winslow, M. M.
10.1101/2024.09.14.613043 — cancer biology — Posted on 2024-09-19
2195 Multi-task benchmarking of single-cell multimodal omics integration methods
Liu, C.; Ding, S.; Kim, J. H.; Long, S.; Xiao, D.; Ghazanfar, S.; Yang, P.
10.1101/2024.09.15.613149 — bioinformatics — Posted on 2024-09-19
2202 Population structure of the endangered Siberian flying squirrel (Pteromys volans) revealed by genomic and mitochondrial data
Ito dos Santos, F.; Lilley, T.; Laine, V. N.; Prost, S.; Kurhinen, J.; Susi, H.; Gashev, S.; Saveljev, A.; Bondarchuk, S.; Babina, S.; Shishikin, A.; Tirski, D.; Vasina, A.; Karpin, V.; Kekkonen, J. A.
10.1101/2024.09.13.612918 — evolutionary biology — Posted on 2024-09-19
2205 Non-cell-autonomous control of gastruloid development by the lncRNA T-UCstem1 through DKK1-dependent modulation of WNT signalling
Coppola, A.; Amoroso, F.; Saracino, F.; Andolfi, G.; Sozzi, E.; Salerno, P.; Zoppoli, P.; Fiorenzano, A.; Merla, G.; Patriarca, E. J.; Minchiotti, G.; Fico, A.
10.1101/2024.09.18.613704 — developmental biology — Posted on 2024-09-19
2206 Droplet Sequencing Reveals Virulence Gene Clusters in Oral Biofilm Extracellular Vesicles
Takano, S.; Takenawa, S.; Divya, N.; Kangmin, Y.; Maehara, T.; Nomura, N.; Obana, N.; Toyofuku, M.; Usui, M.; Ariyoshi, W.; Okamoto, A.
10.1101/2024.09.18.613607 — microbiology — Posted on 2024-09-19
2207 Key roles of microbial sulfur and ammonium oxidizers for the coastal seafloor ecological state
Nilsen, T.; Pettersen, R.; Keeley, N. B.; Ray, J. L.; Majaneva, S.; Stokkan, M.; Hervik, A.; Angell, I. L.; Snipen, L. G.; Sundt, M. O.; Rudi, K.
10.1101/2024.09.19.613430 — microbiology — Posted on 2024-09-19
2208 Global remodeling of ADP-ribosylation by PARP1 suppresses influenza A virus infection
Zhang, Z.; Uribe, I.; Davis, K. A.; McPherson, R. L.; Larson, G. P.; Badiee, M.; Tran, V.; Ledwith, M. P.; Feltman, E.; Yu, S.; Cai, Y.; Chang, C.-Y.; Yang, X.; Ma, Z.; Chang, P.; Kuhn, J. H.; Leung, A. K. L.; Mehle, A.
10.1101/2024.09.19.613696 — microbiology — Posted on 2024-09-19
2212 Generation of an inducible destabilized-domain Cre mouse line to target disease associated microglia
Henningfield, C. M.; Kwang, N.; Tsourmas, K. I.; Neumann, J.; Kawauchi, S.; Swarup, V.; MacGregor, G. R.; Green, K. N.
10.1101/2024.09.18.613773 — neuroscience — Posted on 2024-09-19
2214 Neuronal synchronization in Drosophila
Fernandez-Chiappe, F.; Wappner, M.; Morelli, L. G.; Muraro, N. I.
10.1101/2024.09.19.613913 — neuroscience — Posted on 2024-09-19
2215 Zero-echo time imaging achieves whole brain activity mapping without ventral signal loss in mice
Imamura, A.; Araki, R.; Takahashi, Y.; Miyatake, K.; Kato, F.; Honjoh, S.; Tsurugizawa, T.
10.1101/2024.09.19.613868 — neuroscience — Posted on 2024-09-19
2218 Fresh Human Retinal scRNA-seq Atlas Reveals a Novel Cone Subtype and Cellular Diversity
Yang, L.; Tao, Y.; Pan, Q.; Cai, T.; Ye, Y.; Liu, J.; Zhou, Y.; Shao, Y.; Yi, Q.; Lu, Z. H.; Chen, L.; McKay, G.; Rankin, R.; Meng, W.
10.1101/2024.09.13.612968 — bioinformatics — Posted on 2024-09-19
2219 Integrative modeling in the age of machine learning: a summary of HADDOCK strategies in CAPRI rounds 47-55
Reys, V.; Giulini, M.; Cojocaru, V.; Engel, A. L.; Xu, X.; Roel-Touris, J.; Geng, C.; Ambrosetti, F.; Jimenez-Garcia, B.; Jandova, Z.; Koukos, P. I.; van Noort, C. W.; Teixeira, J. M. C.; van Keulen, S. C.; Reau, M.; Honorato, R. V.; Bonvin, A. M. J. J.
10.1101/2024.09.16.613212 — bioinformatics — Posted on 2024-09-19
2221 Genome-wide profiling of DNA repair proteins identifies higher-order coordination in single cells
de Luca, K. L.; Rullens, P. M.; Karpinska, M. A.; de Vries, S. S.; Gacek-Matthews, A.; Pongor, L. S.; Legube, G.; Jachowicz, J. W.; Oudelaar, A. M.; Kind, J.
10.1101/2023.05.10.540169 — genomics — Posted on 2024-09-19
2225 Insights into Human Norovirus Cultivation in Human Intestinal Enteroids
Ettayebi, K.; Kaur, G.; Patil, K.; Dave, J.; Ayyar, B. V.; Tenge, V. R.; Neil, F. H.; Zeng, X.-L.; Speer, A. L.; Dirienzi, S.; Britton, R. A.; Blutt, S.; Crawford, S. E.; Ramani, S.; Atmar, R. L.; Estes, M. K.
10.1101/2024.05.24.595764 — microbiology — Posted on 2024-09-19
2227 Cell attachment and tail contraction of S. aureus phage phi812
Binovsky, J.; Siborova, M.; Novacek, J.; Bardy, P.; Baska, R.; Skubnik, K.; Botka, T.; Benesik, M.; Pantucek, R.; Tripsianes, K.; Plevka, P.
10.1101/2024.09.19.613683 — microbiology — Posted on 2024-09-19
2228 Characterization and molecular insights of a chromium-reducing bacterium Bacillus tropicus
Tuli, S. R.; Ali, M. F.; Jamal, T. B.; Khan, M. A. S.; Fatima, N.; Ahmed, I.; Khatun, M.; Sharmin, S. A.
10.1101/2024.09.19.613096 — microbiology — Posted on 2024-09-19
2231 Chromosomal instability increases radiation sensitivity
Cosper, P. F.; Paracha, M.; Jones, K. M.; Hrycyniak, L.; Henderson, L.; Bryan, A.; Eyzaguirre, D.; McCunn, E.; Boulanger, E.; Wan, J.; Nickel, K. P.; Horner, V.; Hu, R.; Harari, P. M.; Kimple, R.; Weaver, B. A.
10.1101/2024.09.13.612942 — cancer biology — Posted on 2024-09-19
2232 FLIMPA: A versatile software for Fluorescence Lifetime Imaging Microscopy Phasor Analysis
Kapsiani, S.; Läubli, N. F.; Ward, E. N.; Shehata, M.; Kaminski, C. F.; Kaminski Schierle, G. S.
10.1101/2024.09.13.612802 — biophysics — Posted on 2024-09-19
2234 Clinical phenotypes in acute and chronic infarction explained through human ventricular electromechanical modelling and simulations
Zhou, X.; Wang, Z. J.; Camps, J.; Tomek, J.; Santiago, A.; Quintanas, A.; Vazquez, M.; Vaseghi, M.; Rodriguez, B.
10.1101/2022.02.15.480392 — bioengineering — Posted on 2024-09-19
2235 Identification and comparison of N-glycome profiles from common dietary protein ingredients
Bolino, M.; Avci, I.; Kayili, H. M.; Duman, H.; Salih, B.; Karav, S.; Frese, S. A.
10.1101/2024.09.17.613496 — biochemistry — Posted on 2024-09-19
2238 A within-host infection model to explore tolerance andresistance
Duneau, D.; Pierre, L.; Christine, L.; Parthuisot, N.; Faucher, C.; Xuerong, J.; Buchon, N.; Ferdy, J.-B.
10.1101/2021.10.19.464998 — evolutionary biology — Posted on 2024-09-19
2239 The pericardium forms as a distinct structure during heart formation
Moran, H. R.; Nyarko, O. O.; O'Rourke, R.; Ching, R.-C. R.; Riemslagh, F. W.; Pena, B.; Burger, A.; Sucharov, C. C.; Mosimann, C.
10.1101/2024.09.18.613484 — developmental biology — Posted on 2024-09-19
2240 Global nuclear reorganization during heterochromatin replication in the giant-genome plant Nigella damascena L.
Arifulin, E.; Sorokin, D.; Anoshina, N.; Kuznetsova, M.; Valyaeva, A.; Potashnikova, D.; Omelchenko, D.; Schubert, V.; Kolesnikova, T.; Sheval, E.
10.1101/2023.08.15.552960 — cell biology — Posted on 2024-09-19
2241 Predicting metabolite response to dietary intervention using deep learning
Wang, T.; Holscher, H. D.; Maslov, S.; Hu, F. B.; Weiss, S. T.; Liu, Y.-Y.
10.1101/2023.03.14.532589 — microbiology — Posted on 2024-09-19
2242 A T6SS DNase effector induces nuclear DNA Damage to trigger apoptosis via activation of the cGAS-STING-TNF axis
Song, L.; Xu, L.; Zhang, P.; Li, S.; Zhao, Y.; Shi, Z.; Ma, R.; Li, Y.; Wang, Y.; Wei, G.; Shen, X.
10.1101/2024.09.19.613802 — microbiology — Posted on 2024-09-19
2243 TYPE THREE SECRETION SYSTEM-INDUCED MECHANOPORATION OF VACUOLAR MEMBRANES
SWISTAK, L.; Albert, M.; Valenzuela, C.; Gokerkucuk, E. B.; Bontems, F.; Gazi, A. D.; Tachon, S.; Sartori-Rupp, A.; Lesser, C. F.; Paul-Gilloteaux, P.; Tinevez, J.-Y.; Vos, M.; Enninga, J.
10.1101/2024.09.19.613840 — microbiology — Posted on 2024-09-19
2244 Microbiome-based correction for random errors in nutrient profiles derived from self-reported dietary assessments
Wang, T.; Fu, Y.; Shuai, M.; Zheng, J.-S.; Zhu, L.; Chan, A. T.; Sun, Q.; Hu, F. B.; Weiss, S. T.; Liu, Y.-Y.
10.1101/2023.11.21.568102 — microbiology — Posted on 2024-09-19
2245 Sympathetic innervation of interscapular brown adipose tissue is not a predominant mediator of OT-elicited reductions of body weight gain and adiposity in male diet-induced obese rats
Edwards, M. M.; Nguyen, H. K.; Dodson, A. D.; Herbertson, A. J.; Honeycutt, M. K.; Slattery, J. D.; Rambousek, J. R.; Tsui, E.; Wolden-Hanson, T.; Wietecha, T. A.; Graham, J. L.; Tapia, G. P.; Sikkema, C. L.; O'Brien, K. D.; Mundinger, T. O.; Peskind, E. R.; Ryu, V.; Havel, P. J.; Khan, A. M.; Tabosky, G. J.; Blevins, J. E.
10.1101/2024.09.12.612710 — neuroscience — Posted on 2024-09-19
2247 Is there a ubiquitous spectrolaminar motif of local field potential power across primate neocortex?
Mackey, C. A.; Duecker, K.; Neymotin, S. A.; Dura-Bernal, S.; Haegens, S.; Barczak, A.; O'Connell, M. N.; Jones, S.; Ding, M.; Ghuman, A. S.; Schroeder, C. E.
10.1101/2024.09.18.613490 — neuroscience — Posted on 2024-09-19
2254 Pharmacological Inhibition of Epac1 Protects against Pulmonary Fibrosis by Blocking FoxO3a Neddylation
Jankowski, K.; Lemay, S. E.; Lozano-Ojalvo, D.; Perez Rodriguez, L.; Sauvaget, M.; Breuils-Bonnet, S.; Formoso, K.; Jagana, V.; Zhang, S.; Milara, J.; Cortijo, J.; Turnbull, I. C.; Provencher, S.; Bonnet, S.; Orchando, J.; Lezoualch, F.; Bisserier, M.; Hadri, L.
10.1101/2024.09.13.612935 — physiology — Posted on 2024-09-19
2255 Plasma exosomes from individuals with type 2 diabetes drive breast cancer aggression in patient-derived organoids
Ennis, C. S.; Seen, M.; Chen, A.; Kang, H.; Ilinski, A.; Mahdaviani, K.; Ko, N. Y.; Monti, S.; Denis, G. V.
10.1101/2024.09.13.612950 — cancer biology — Posted on 2024-09-19
2257 Tension-induced suppression of allosteric conformational changes explains coordinated stepping of kinesin-1
Makino, T.; Kanada, R.; Mori, T.; Miyazono, K.-i.; Komori, Y.; Yanagisawa, H.; Takada, S.; Tanokura, M.; Kikkawa, M.; Tomishige, M.
10.1101/2024.09.19.613825 — biophysics — Posted on 2024-09-19
2261 Sidechain chemistry-encoded solid/liquid phase transitions of condensates
Chen, F.; Han, Y.; Li, X.; Guo, W.; Wu, C.; Xia, J.; Zeng, X.; Shum, H. C.
10.1101/2024.09.16.613107 — biophysics — Posted on 2024-09-19
2263 Comprehensive mapping of the Interaction of levodopa and iron metabolism in Parkinson's disease
Wang, J.; Ekambaram, S.; Huang, X.; Mailman, R. B.; Proctor, E. A.; Dokholyan, N. V.
10.1101/2024.09.13.612928 — bioinformatics — Posted on 2024-09-19
2266 QuickEd: High-performance exact sequence alignment based on bound-and-align
Doblas, M.; Lostes-Cazorla, O.; Aguado-Puig, Q.; Iniguez, C.; Moreto, M.; Marco-Sola, S.
10.1101/2024.09.13.612714 — bioinformatics — Posted on 2024-09-19
2267 Polyacrylamide-based Antimicrobial Copolymers Immune to Typical Resistance Mechanisms to Replace or Rescue Antibiotics
Williams, S. C.; Chosy, M. B.; Jons, C. K.; Dong, C.; Prossnitz, A. N.; Liu, X.; Lopez Hernandez, H.; Cegelski, L.; Appel, E.
10.1101/2024.09.13.612993 — bioengineering — Posted on 2024-09-19
2269 LiverMap pipeline for 3D imaging of human liver reveals volumetric spatial dysregulation of cirrhotic vasculobiliary architecture
Fabyan, W. B.; Fortin, C. L.; Kenerson, H. L.; Simmonds, S. P.; Liu, J. T. C.; Yeh, M. M.; Carr, R. M.; Yeung, R. S. W.; Stevens, K. R.
10.1101/2024.09.14.613049 — bioengineering — Posted on 2024-09-19
2270 The mechanism of peptidoglycan O-acetylation in Gram-negative bacteria typifies bacterial MBOAT-SGNH acyltransferases
Anderson, A. C.; Schultz, B. J.; Snow, E. D.; Brott, A. S.; Stangherlin, S.; Malloch, T.; London, J. R.; Walker, S.; Clarke, A. J.
10.1101/2024.09.17.613324 — biochemistry — Posted on 2024-09-19
2272 Dissecting earthworm diversity in tropical rainforests
Goulpeau, A.; Hedde, M.; Ganault, P.; Lapied, E.; Maggia, M.-E.; Marcon, E.; Decaens, T.
10.1101/2024.09.13.612984 — ecology — Posted on 2024-09-19
2273 A workflow for microclimate sensor networks: integrating geographic tools, statistics, and local knowledge
Klinges, D. H.; Lembrechts, J.; Van de Vondel, S.; Greenlee, E.; Hayles-Cotton, K.; Senior, R.
10.1101/2024.09.13.612939 — ecology — Posted on 2024-09-19
2274 Ancient DNA reveals historical demographic decline and genetic erosion in the Atlantic bluefin tuna
Andrews, A. J.; Eriksen, E. F.; Star, B. J.; Praebel, K.; Di Natale, A.; Malca, E.; Zapfe, G.; Onar, V.; Aniceti, V.; Carenti, G.; Piques, G.; Nielsen, S. V.; Persson, P.; Piattoni, F.; Fontani, F.; Atmore, L. M.; Kersten, O.; Tinti, F.; Cilli, E.; Cariani, A.
10.1101/2024.09.14.613028 — ecology — Posted on 2024-09-19
2275 Genetic variation in the activity of a TREM2-p53 signaling axis determines oxygen-inducedlung injury
Abe, Y.; Spann, N. J.; Tang, W.; Zeng, F.; Richard, J. L. C.; Seymour, C.; Jansky, S.; Mooney, M.; Huff, R.; Chanthavixay, K.; Dhar, D.; Ganguly, S.; Guo, J. L.; Lopez, D. M.; Longaker, M. T.; Benner, C.; Glass, C.; Sajti, E.
10.1101/2024.09.13.612775 — immunology — Posted on 2024-09-19
2277 Design and immunogenicity of an HIV-1 clade C pediatric envelope glycoprotein stabilized by multiple platforms
Kumar, S.; del Moral-Sanchez, I.; Singh, S.; Newby, M. L.; Allen, J. D.; Bijl, T. P.; Vaghani, Y.; Jing, L.; Ortlund, E. A.; Crispin, M.; Patel, A.; Sanders, R. W.; Luthra, K.
10.1101/2024.09.14.613016 — immunology — Posted on 2024-09-19
2281 Biocontrol of bacterial wilt disease using plant-associated bacterial communities in tomato
Tanaka, E.; Umeki, D.; Kido, S.; Makishima, R.; Tamaki, Y.; Murakami, T.; Fujiwara, M.; Saijo, Y.
10.1101/2024.09.14.613082 — plant biology — Posted on 2024-09-19
2282 Engineering Rubisco Condensation in Chloroplasts to Manipulate Plant Photosynthesis
Chen, T.; Hojka, M.; Davey, P.; Sun, Y.; Zhou, F.; Lawson, T.; Nixon, P.; Lin, Y.; Liu, L.-N.
10.1101/2024.09.16.613299 — plant biology — Posted on 2024-09-19
2283 Arabidopsis AtGELP53 modulates polysaccharide acetylation and defense response through oligosaccharide-mediated signaling
Rastogi, L.; Hussain, M.-M.; Tyagi, S.; Kabyashree, K.; Kharbanda, N.; Maiti, T. K.; Krishnan, V.; Jha, G.; Voxeur, A.; Pawar, P. A.-M.
10.1101/2024.09.16.613205 — plant biology — Posted on 2024-09-19
2284 Joint operation of the CO2 concentrating mechanism and photorespiration in green algae during acclimation to limiting CO2
Dao, O.; Bertrand, M.; Alseekh, S.; Veillet, F.; Auroy, P.; Nguyen, P.-C.; Legeret, B.; Epting, V.; Morin, A.; Cuine, S.; Monteil, C.; Mackinder, L. C. M.; Burlacot, A.; Krieger-Liszkay, A.; Weber, A. P. M.; Fernie, A. R.; Peltier, G.; Li-Beisson, Y.
10.1101/2024.09.18.613642 — plant biology — Posted on 2024-09-19
2285 Plant BCL-Domain Homologues play a conserved role in SWI/SNF complex stability
Candela-Ferre, J.; Perez-Alemany, J.; Diego-Martin, B.; Pandey, V.; Wohlschlegel, J.; Lozano-Juste, J.; Gallego-Bartolome, J.
10.1101/2024.09.17.612632 — plant biology — Posted on 2024-09-19
2287 Fine-Tuning TAWAWA1-Mediated Panicle Architecture by Genome Editing of a Downstream Conserved Noncoding Sequence in Rice
Kuroha, T.; Lombardo, F.; Iwasaki, W. M.; Chechetka, S.; Kawahara, Y.; Yoshida, A.; Kyozuka, J.; Makino, T.; Yoshida, H.
10.1101/2024.09.17.612847 — plant biology — Posted on 2024-09-19
2289 PGR5 promotes energy-dependent non-photochemical quenching to enable efficient C4 photosynthesis under fluctuating light
Woodford, R.; Watkins, J.; Moore, M.; Nix, S. J.; Yee, S.; Chan, K. X.; Pogson, B. J.; von Caemmerer, S.; Furbank, R. T.; Ermakova, M.
10.1101/2024.09.15.613160 — plant biology — Posted on 2024-09-19
2294 Genomic imprinting in an early-diverging angiosperm reveals ancient mechanisms for seed initiation in flowering plants
Florez-Rueda, A. M.; Scharmann, M.; de Souza, L. P.; Fernie, A. R.; Bachelier, J. B.; Figueiredo, D. D.
10.1101/2024.09.18.613646 — plant biology — Posted on 2024-09-19
2297 Toxoplasma gondii chronic infection decreases visceral nociception through peripheral opioid receptor signaling
Audibert, A.; Mas-Orea, X.; Rey, L.; Belloy, M.; Bassot, E.; Marodon, G.; Masson, F.; Cenac, N.; Dietrich, G.; Bonnart, C.; Blanchard, N.
10.1101/2024.09.13.612908 — physiology — Posted on 2024-09-19
2298 Increased Inflammation as well as Decreased Endoplasmic Reticulum Stress and Translation Differentiate Pancreatic Islets of Pre-symptomatic Stage 1 Type 1 Diabetes and Non-diabetic Cases
Swensen, A. C.; Piehowski, P.; Chen, J.; Chan, X. Y.; Kelly, S. S.; Petyuk, V. A.; Moore, R. J.; Nasif, L.; Butterworth, E. A.; Atkinson, M. A.; Kulkarni, R. N.; Campbell-Thompson, M.; Mathews, C. E.; QIAN, W.-J.
10.1101/2024.09.13.612933 — pathology — Posted on 2024-09-19
2302 Glycoinformatic profiling of label-free intact heparan sulfate oligosaccharides
Maciej-Hulme, M. L.; Kim, J.; Roberts, E. T.; Zhang, Y.; van der Velden, A.; den Braanker, D.; Yanginlar, C.; de Graaf, M.; Rabelink, T.; van den Berg, B.; van Omen, E.; Maas, R.; van de Logt, A.-E.; Amster, I. J.; van der Vlag, J.
10.1101/2024.09.18.613784 — bioinformatics — Posted on 2024-09-19
2305 Population genomics of Plasmodium ovale species in sub-Saharan Africa
Carey-Ewend, K.; Popkin-Hall, Z. R.; Simkin, A.; Muller, M.; Hennelly, C.; He, W.; Moser, K.; Gaither, C.; Niare, K.; Aghakanian, F.; Feleke, S.; Brhane, B. G.; Phanzu, F.; Mwandagalirwa, K.; Aydemir, O.; Sutherland, C.; Ishengoma, D. S.; Ali, I. M.; Ngasala, B.; Kalonji, A.; Tshefu, A.; Parr, J.; Bailey, J. A.; Juliano, J. J.; Lin, J. T.
10.1101/2024.04.10.588912 — genomics — Posted on 2024-09-19
2307 Transcriptomic landscape of sex differences in obesity and type 2 diabetes in subcutaneous adipose tissue
Moldovan, R. A.; Hidalgo, M. R.; Castane, H.; Jimenez-Franco, A.; Joven, J.; Burks, D. J.; Galan, A.; Garcia-Garcia, F.
10.1101/2024.09.18.613678 — molecular biology — Posted on 2024-09-19
2308 The human blood harbors a phageome which differs in Crohn's disease
Lamy-Besnier, Q.; Theodorou, I.; Billaud, M.; Zhang, H.; Brot, L.; Culot, A.; Abriat, G.; Sokol, H.; DePaepe, M.; Petit, M.-A.; De Sordi, L.
10.1101/2024.06.04.597176 — microbiology — Posted on 2024-09-19
2309 A system for functional studies of the major virulence factor of malaria parasites
Cronshagen, J.; Allweier, J.; Mesen-Ramirez, P.; Staecker, J.; Vaaben, A. V.; Ramon-Zamorano, G.; Naranjo, I.; Ofori, S.; Jansen, P. W.; Hornebeck, J.; Kieferle, F.; Murk, A.; Martin, E.; Castro-Pena, C.; Bartfai, R.; Lavstsen, T.; Bruchhaus, I.; Spielmann, T.
10.1101/2024.04.30.591946 — microbiology — Posted on 2024-09-19
2310 Structural and immunological characterization of the H3 influenza hemagglutinin during antigenic drift
de Paiva Froes Rocha, R.; Tomris, I.; Bowman, C. A.; Stevens, E.; Kantorow, J.; Peng, W.; Oeverdieck, S.; Ferguson, J. A.; Jung, D. D.; Herfst, S.; Snijder, J.; Chakraborty, S.; Torrents de la Pena, A.; Berndsen, Z. T.; de Vries, R. P.; Ward, A. B.
10.1101/2024.09.13.612776 — immunology — Posted on 2024-09-19
2311 Th17 cells require the DNA repair sensor XPC to control oxidative DNA damage
Leite, J. A.; Notaberardino Bos, N.; Menezes, L.; Martins, E.; da Silva Leandro, G.; da Silva, P.; Ranfley, H.; Oliveira, S.; Pontes Ferreira, C.; Arimateia de Oliveira Nery Neto, J.; Yuji, V.; Cipelli, M.; Leocata, B.; Goncalves, T.; Gabry da Silveira, A.; Baroni, S.; L. Weiner, H.; Hofmann, T.; Scheu, S.; Machado Colli, L.; Waisman, A.; Muxel, S.; Menck, C. F.; Saraiva Camara, N. O.
10.1101/2024.09.13.612834 — immunology — Posted on 2024-09-19
2314 Preclinical validation and kinetic modelling of the SV2A PET ligand UCB-J in mice
Everix, L.; Elvas, F.; Miranda, A.; Khetarpal, V.; Liu, L.; Bard, J.; Staelens, S.; Bertoglio, D.
10.1101/2024.07.10.602899 — neuroscience — Posted on 2024-09-19
2315 Small DNA elements that act as both insulators and silencers in plants
Jores, T.; Mueth, N. A.; Tonnies, J.; Char, S. N.; Liu, B.; Grillo-Alvarado, V.; Abbitt, S.; Anand, A.; Deschamps, S.; Diehn, S.; Gordon-Kamm, B.; Jiao, S.; Munkvold, K.; Snowgren, H.; Sardesai, N.; Fields, S.; Yang, B.; Cuperus, J.; Queitsch, C.
10.1101/2024.09.13.612883 — plant biology — Posted on 2024-09-19
2317 Manufacturing-Aware Generative Model Architectures Enable Biological Sequence Design and Synthesis at Petascale
Weinstein, E. N.; Gollub, M. G.; Slabodkin, A.; Gardner, C. L.; Dobbs, K.; Cui, X.-B.; Amin, A. N.; Church, G. M.; Wood, E. B.
10.1101/2024.09.13.612900 — bioengineering — Posted on 2024-09-19
2321 Multiplexed spatial mapping of chromatin features, transcriptome, and proteins in tissues
Guo, P.; Mao, L.; Chen, Y.; Lee, C. N.; Cardilla, A.; Li, M.; Bartosovic, M.; Deng, Y.
10.1101/2024.09.13.612892 — genetics — Posted on 2024-09-19
2322 Mitochondrial superoxide acts in the intestine to extend longevity
Liontis, T.; Senchuk, M. M.; Zhu, S.; Jacob-Tomas, S.; Anglas, U.; Traa, A.; Soo, S. K.; Van Raamsdonk, J. M.
10.1101/2024.09.13.612915 — genetics — Posted on 2024-09-19
2323 Most Beefalo cattle have no detectable bison genetic ancestry
Shapiro, B.; Oppenheimer, J.; Heaton, M. P.; Kuhn, K. L.; Green, E.; Blackburn, H. D.; Smith, T. P. L.
10.1101/2024.09.16.613218 — evolutionary biology — Posted on 2024-09-19
2324 Adaptation to climate in the native and introduced ranges of a cosmopolitan plant
Albano, L. J.; Bastias, C. C.; Estarague, A.; Hendrickson, B. T.; Innes, S. G.; King, N.; Patterson, C. M.; Tudoran, A.; Vasseur, F.; Puentes, A.; Violle, C.; Kooyers, N. J.; Johnson, M. T.
10.1101/2024.09.16.613311 — evolutionary biology — Posted on 2024-09-19
2327 Beta cell extracellular vesicle PD-L1 as a novel regulator of CD8+ T cell activity and biomarker during the evolution of Type 1 Diabetes
Rao, C.; Cater, D. T.; Roy, S.; Xu, J.; Olivera, A. D. G.; Evans-Molina, C.; Eizirik, D. L.; Piganelli, J. D.; Mirmira, R.; Sims, E. K.
10.1101/2024.09.18.613649 — cell biology — Posted on 2024-09-19
2328 Is there a ubiquitous spectrolaminar motif of local field potential power across primate neocortex?
Mackey, C. A.; Duecker, K.; Neymotin, S. A.; Dura-Bernal, S.; Haegens, S.; Barczak, A.; O'Connell, M. N.; Jones, S.; Ding, M.; Ghuman, A. S.; Schroeder, C. E.
10.1101/2024.09.18.613490 — neuroscience — Posted on 2024-09-19
2332 AyurPhenoClusters define common molecular roots for rare diseases and uncover ciliary dysfunctions in syndromic conditions
Joshi, A.; Jangir, D.; Sharma, A.; Anand, T.; Verma, H.; Yadav, M.; Rangani, N.; Joshi, P.; Singh, R. P.; Kumar, S.; Girdhar, S.; Sharma, R.; Kumar, A.; Dey, L.; Mukerji, M.
10.1101/2024.09.13.612844 — genetics — Posted on 2024-09-19
2333 Ecotype formation in the European anchovy fuelled by structural variants of different origins and genetic interactions with a southern lineage
Meyer, L.; Barry, P.; Arbiol, C.; Castilho, R.; Van der Lingen, C. D.; Chlaïda, M.; McKeown, N. J.; Ernande, B.; Le Moan, A.; Bonhomme, F.; Gagnaire, P.-A.; Guinand, B.
10.1101/2024.09.15.613121 — evolutionary biology — Posted on 2024-09-19
2334 Directional Cell-to-cell Transport in Plant Roots
Jacquier, L.; Fiorenza, C.; Robe, K.; Han, J.-P.; Cleard, F.; Fuchs, C.; Ramakrishna, P.; Loubery, S.; Lefebvre-Legendre, L.; Barberon, M.
10.1101/2024.09.16.613234 — plant biology — Posted on 2024-09-19
2342 The pericardium forms as a distinct structure during heart formation
Moran, H. R.; Nyarko, O. O.; O'Rourke, R.; Ching, R.-C. R.; Pena, B.; Riemslagh, F. W.; Burger, A.; Sucharov, C. C.; Mosimann, C.
10.1101/2024.09.18.613484 — developmental biology — Posted on 2024-09-19
2344 Development and evaluation of a non-invasive brain-spine interface using transcutaneous spinal cord stimulation
Atkinson, C. J.; Lombardi, L.; Lang, M.; Keesey, R. E.; Hawthorn, R.; Seitz, Z.; Leuthardt, E. C.; Brunner, P.; Seanez, I.
10.1101/2024.09.16.612897 — neuroscience — Posted on 2024-09-19
2346 Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi-Goutieres Syndrome neuropathology
Nemec, K. M.; Uy, G.; Chaluvadi, V. S.; Purnell, F. S.; Elfayoumi, B.; O'Brien, C.; Aisenberg, W. H.; Lombroso, S. I.; Guo, X.; Blank, N.; Oon, C. H.; Yaqoob, F.; Temsamrit, B.; Rawat, P.; Thaiss, C.; Wang, Q.; Bennett, M. L.; Bennett, F. C.
10.1101/2024.09.18.613629 — neuroscience — Posted on 2024-09-19
2351 Intra-hypothalamic circuit orchestrates β-endorphin release following coital ejaculation in male mice
Zha, X.; Jiao, Z.; Li, S.-S.; Liu, X.-Y.; Li, X.-Y.; Sun, Y.-Z.; Ding, X.-J.; Gao, M.-T.; Gao, S.-C.; Chen, A.-X.; Lin, J.-K.; Zhang, W.; Cao, X.-Z.; Zhang, Y.-L.; Yang, R.-R.; Xu, C.; Xu, X.-H.
10.1101/2024.09.18.613624 — neuroscience — Posted on 2024-09-19
2356 Alpha-synuclein preformed fibril-induced aggregation and dopaminergic cell death in cathepsin D overexpression and ZKSCAN3 knockout mice
Mueller, T.; Jeffrey, P.; He, Y.; Ouyang, X.; Westbrook, D.; Darley-Usmar, V.; Goldberg, M. S.; Volpicelli-Daley, L.; Zhang, J.
10.1101/2024.09.18.613763 — neuroscience — Posted on 2024-09-19
2357 Human Neural Organoid Microphysiological Systems Show the Building Blocks Necessary for Basic Learning and Memory
Alam El Din, D.-M.; Moenkemoeller, L.; Loeffler, A.; Habibollahi, F.; Schenkman, J.; Mitra, A.; van der Molen, T.; Ding, L.; Laird, J.; Schenke, M.; Johnson, E.; Kagan, B.; Hartung, T.; Smirnova, L.
10.1101/2024.09.17.613333 — neuroscience — Posted on 2024-09-19
2359 Neural basis of collective social behavior during environmental challenge
Raam, T.; Li, Q.; Gu, L.; Elagio, G.; Lim, K. Y.; Zhang, X.; Correa, S. M.; Hong, W.
10.1101/2024.09.17.613378 — neuroscience — Posted on 2024-09-19
2360 FUS controls muscle differentiation and structure through LLPS mediated recruitment of MEF2 and ETV5
Picchiarelli, G.; Wienand, A.; Megat, S.; Aly, A.; Been, M.; Mishra, N.; Hutten, S.; Sternburg, E.; Cauchy, P.; Dieterle, S.; Catinozzi, M.; Demais, V.; Tzeplaeff, L.; Huebers, A.; Zeuschner, D.; Rosenbohm, A.; Ludolph, A. C.; Boutillier, A.-L.; Boeckers, T.; Dormann, D.; Demestre, M.; Sellier, C.; Lagier-Tourenne, C.; Storkebaum, E.; Dupuis, L.
10.1101/2024.09.18.613669 — neuroscience — Posted on 2024-09-19
2361 On the specificity of manual triggers of autonomic nervous system responses using osteopathic cranial manipulative medicine
Keller, M.; Perlitz, V.; Pelz, H.; Borik, S.; Repik, I.; Geilgens, A.; Cotuk, B.; Müller, G.; Mathiak, K.; Mayer, J.
10.1101/2024.09.11.612567 — physiology — Posted on 2024-09-19
2362 Craters on the melanoma surface facilitate tumor-immune interactions and demonstrate pathologic response to checkpoint blockade in humans
Ludin, A.; Stirtz, G. L.; Tal, A.; Nirmal, A. J.; Besson, N.; Jones, S. M.; Pfaff, K. L.; Manos, M.; Liu, S.; Barrera, I.; Gong, Q.; Rodrigues, C. P.; Sahu, A.; Jerison, E.; Alessi, J. V.; Ricciuti, B.; Richardson, D. S.; Weiss, J. D.; Moreau, H. M.; Stanhope, M. E.; Afeyan, A. B.; Sefton, J.; McCall, W. D.; Formato, E.; Yang, S.; Zhou, Y.; Hoytema van Konijnenburg, D. P.; Cole, H. L.; Cordova, M.; Deng, L.; Rajadhyaksha, M.; Quake, S. R.; Awad, M. M.; Chen, F.; Sorger, P. K.; Hodi, F. S.; Rodig, S. J.; Murphy, G. F.; Zon, L. I.
10.1101/2024.09.18.613595 — cancer biology — Posted on 2024-09-19
2364 Single unit electrophysiology recordings and computational modeling can predict octopus arm movement
Gedela, N. S. S.; Salim, S.; Radawiec, R. D.; Richie, J. M.; Chestek, C. A.; Draelos, A.; Pelled, G.
10.1101/2024.09.13.612676 — bioengineering — Posted on 2024-09-19
2366 The Gq/11 family of Gα subunits is necessary and sufficient for lower jaw development
Kanai, S. M.; Garcia, C. R.; Augustus, M. R.; Sharafeldeen, S. A.; Brooks, E. P.; Sucharov, J.; Lencer, E. S.; Nichols, J. T.; Clouthier, D. E.
10.1101/2024.09.17.611698 — developmental biology — Posted on 2024-09-19
2367 Mylpf dosage is proportionate to fast-twitch myofibril size in the zebrafish embryo
Adekeye, T. E.; Teets, E. M.; Tomak, E. A.; Waterman, S. L.; Sprague, K. A.; White, A.; Coffin, M. L.; Varga, S. M.; Easterbrooks, T. E.; Shepherd, S. J.; Austin, J. D.; Krivorotko, D.; Hupper, T. E.; Kelley, J. B.; Amacher, S. L.; Talbot, J. C.
10.1101/2024.09.18.613721 — developmental biology — Posted on 2024-09-19
2371 The transcriptomic landscape of spinal V1 interneurons reveals a role for En1 in specific elements of motor output
Trevisan, A. J.; Han, K.; Chapman, P.; Kulkarni, A. S.; Hinton, J. M.; Ramirez, C.; Klein, I.; Gatto, G.; Gabitto, M. I.; Menon, V.; Bikoff, J. B.
10.1101/2024.09.18.613279 — neuroscience — Posted on 2024-09-19
2372 Lateralized cerebellar connectivity differentiates auditory pathways in echolocating and non-echolocating whales
Flem, S. A.; Berns, G.; Inglis, B.; Niederhut, D.; Montie, E.; Deacon, T.; Miller, K. L.; Tyack, P.; Cook, P. F.
10.1101/2024.09.18.609772 — neuroscience — Posted on 2024-09-19
2373 The mechanism and consequences of amyloid-β modulating thiamine pyrophosphokinase-1 expression in microglia
Cheng, X.; Zhao, R.; Qiu, H.; Song, P.; Kou, L.; Sang, S.; Xia, Y.; Cai, W.; Jin, B.; Huang, Q.; Yuan, P.; Zhong, C.
10.1101/2024.09.18.613405 — neuroscience — Posted on 2024-09-19
2374 Incorporating buccal mass planar mechanics and anatomical features improves neuromechanical modeling of Aplysia feeding behavior
Bennington, M. J.; Liao, A. S.; Sukhnandan, R.; Kundu, B.; Rogers, S. M.; Gill, J. P.; McManus, J. M.; Sutton, G. P.; Chiel, H. J.; Webster-Wood, V. A.
10.1101/2024.09.17.613591 — neuroscience — Posted on 2024-09-19
2376 Optogenetic stimulation of dorsal striatum bidirectionally controls seizures
Hyder, S. K.; Lazarini-Lopes, W.; Toib, J.; Williams, G.; Sukharev, A.; Forcelli, P. A.
10.1101/2024.09.18.613710 — neuroscience — Posted on 2024-09-19
2378 Ventrolateral prefrontal cortex in macaques guides decisions in different learning contexts
Fujimoto, A.; Elorette, C.; Fujimoto, S. H.; Fleysher, L.; Russ, B. E.; Rudebeck, P. H.
10.1101/2024.09.18.613767 — neuroscience — Posted on 2024-09-19
2379 Cortico-hippocampal interactions underlie schema-supported memory encoding in older adults
Huang, S.; Bogdan, P. C.; Howard, C. M.; Gillette, K.; Deng, L.; Welch, E.; McAllister, M. L.; Giovanello, K. S.; Davis, S. W.; Cabeza, R.
10.1101/2024.09.18.613755 — neuroscience — Posted on 2024-09-19
2385 Transcriptional program-based deciphering of the MET exon 14 skipping regulation network
Truong, M.-J.; Pawlak, G.; Meneboo, J.-P.; Sebda, S.; Fernandes, M.; Figeac, M.; Elati, M.; Tulasne, D.
10.1101/2024.09.13.612820 — cancer biology — Posted on 2024-09-19
2387 Interpretable high-resolution dimension reduction of spatial transcriptomics data by DeepFuseNMF
Tang, J.; Chen, Z.; Qian, K.; Huang, S.; He, Y.; Yin, S.; He, X.; Ye, B.; Zhuang, Y.; Meng, H.; Xi, J.; Xi, R.
10.1101/2024.09.12.612666 — bioinformatics — Posted on 2024-09-19
2389 Benchmarking the identification of a single degraded protein to explore optimal search strategies for ancient proteins
Rodriguez Palomo, I.; Nair, B. A. B.; Chiang, Y.; Dekker, J.; Dartigues, B.; Mackie, M.; Evans, M.; Macleod, R.; Olsen, J.; Collins, M. J.
10.1101/2023.12.15.571577 — bioinformatics — Posted on 2024-09-19
2391 Evaluation of altered cell-cell communication between glia and neurons in the hippocampus of 3xTg-AD mice at two time points
Soelter, T. M.; Howton, T. C.; Wilk, E. J.; Whitlock, J. H.; Clark, A. D.; Birnbaum, A.; Patterson, D. C.; Cortes, C. J.; Lasseigne, B. N.
10.1101/2024.05.21.595199 — genomics — Posted on 2024-09-19
2392 Conserved Evolutionary Response to Whole Genome Duplication in Angiosperms Revealed Using High Resolution Gene Expression Profiling
Leal, J. L.; Hodkova, E.; Billhardt, A.; Eklund, D. M.; Granath, G.; Herrera Egoavil, P.; Chen, J.; Milesi, P.; Salojärvi, J.; Lascoux, M.
10.1101/2024.09.12.612700 — evolutionary biology — Posted on 2024-09-19
2393 RIPK1 is essential for Herpes Simplex Virus-triggered ZBP1-dependent necroptosis in human cells
Amusan, O. T.; Wang, S.; Yin, C.; Koehler, H. S.; Li, Y.; Tenev, T.; Wilson, R.; Bellenie, B.; Zhang, T.; Wang, J.; liu, c.; seong, k.; Poorbaghi, S. L.; Yates, J.; Shen, Y.; Upton, J. W.; Meier, P.; Balachandra, S.; Guo, H.
10.1101/2024.09.17.613393 — cell biology — Posted on 2024-09-19
2394 Substrate-specific regulation of mTORC1 activity by G protein-coupled receptors
Atkinson, S. J.; Ritchie, W. V.; Thompson, K.; Thompson, D.; Hislop, J. N.; Hatakeyama, R.
10.1101/2024.09.18.613687 — cell biology — Posted on 2024-09-19
2395 iTRVZ: liquid nano-platform for signal integration on the plasma membrane
Tsunoyama, T. A.; Hoffmann, C.; Tang, B.; Hirosawa, K. M.; Nemoto, Y. L.; Kasai, R. S.; Fujiwara, T.; Suzuki, K. G.; Milovanovic, D.; Kusumi, A.
10.1101/2021.12.30.474523 — cell biology — Posted on 2024-09-19
2397 Development of a cell-permeable Biotin-HaloTag ligand to explore functional differences between protein variants across cellular generations
Yadav, A. K.; Jadhav, A. S.; Szczepanik, P.; Fagherazzi, P.; Kabelka, I.; Vacha, R.; Svenda, J.; Polasek-Sedlackova, H.
10.1101/2024.09.18.613519 — cell biology — Posted on 2024-09-19
2398 Differential translocation of bacteriophages across the intestinal barrier in health and Crohn's disease
Douadi, C.; Theodorou, I.; Lamy-Besnier, Q.; Sbardella, Y.; Brot, L.; Costantini, P. E.; Saporetti, R.; Danielli, A.; Calvaresi, M.; De Paepe, M.; Sokol, H.; Garcia-Weber, D.; Carriere, V.; Thenet, S.; De Sordi, L.
10.1101/2024.09.17.613249 — cell biology — Posted on 2024-09-19
2400 Natural Killer Cell Dysfunction In Human Bladder Cancer Is Caused By Tissue-Specific Suppression of SLAMF6 Signaling
Farkas, A. M.; Youssef, D.; Tran, M. A.; Balan, S.; Newman, J. H.; Audenet, F.; Anastos, H.; Velazquez, L. G.; Peros, A.; Ananthanarayanan, A.; Daza, J.; Gonzalez-Gugel, E.; Sadanala, K.; Theorell, J.; Galsky, M. D.; Horowitz, A.; Sfakianos, J. P.; Bhardwaj, N.
10.1101/2024.04.30.591366 — immunology — Posted on 2024-09-19
2401 A neural mechanism for learning from delayed postingestive feedback
Zimmerman, C. A.; Bolkan, S. S.; Pan-Vazquez, A.; Wu, B.; Keppler, E. F.; Meares-Garcia, J. B.; Guthman, E. M.; Fetcho, R. N.; McMannon, B.; Lee, J.; Hoag, A. T.; Lynch, L. A.; Janarthanan, S. R.; Lopez Luna, J. F.; Bondy, A. G.; Falkner, A. L.; Wang, S. S.-H.; Witten, I. B.
10.1101/2023.10.06.561214 — neuroscience — Posted on 2024-09-19
2404 Localization of Albumin with Correlative Super Resolution Light- and Electron Microscopy in the Kidney
Birtasu, A. N.; Ermel, U. H.; Rahm, J. V.; Seybert, A.; Flottmann, B.; Heilemann, M.; Grahammer, F.; Frangakis, A. S.
10.1101/2024.09.16.613238 — biophysics — Posted on 2024-09-19
2405 Mechanical Profiling of Biopolymer Condensates through Acoustic Trapping
Nakajima, K.; Sneideris, T.; Good, L. L.; Erkamp, N. A.; Ogi, H.; Knowles, T.
10.1101/2024.09.16.613217 — biophysics — Posted on 2024-09-19
2406 De-novo design of actively spinning and gyrating spherical micro-vesicles
Kaur, V.; Khuntia, S. S.; Taneja, C.; Chaudhuri, A.; Yogendran, K. P.; Rakshit, S.
10.1101/2024.09.17.613442 — biophysics — Posted on 2024-09-19
2409 The binary protein interactome mapping of the Giardia lamblia proteasome lid reveals extra proteasomal functions of GlRpn11
Das, A.; Ray, A.; Chaudhuri, N. R.; Mukherjee, S.; Dastidar, S. G.; Ghosh, A.; Ganguly, S.; Jana, K.; Sarkar, S.
10.1101/2024.09.18.613619 — cell biology — Posted on 2024-09-19
2410 Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies
Stoddard, E. G.; Fang, L.; Zhong, Y.; Potter, Z. E.; Brush, D. S.; Simon, J. J.; Golkowski, M.; Maly, D. J.
10.1101/2024.09.18.613772 — cell biology — Posted on 2024-09-19
2411 Bacterial Receptors but Not Anti-Phage Defence Mechanisms Determine Host Range for a Pair of Pseudomonas aeruginosa Lytic Phages
Mueller, D. M.; Pourtois, J.; Kim, K. M.; Targ, B.; Burgener, E.; Milla, C.; McBride, R.; Antani, J.; Turner, P. E.; Koff, J.; Bollyky, P.
10.1101/2024.04.30.591980 — microbiology — Posted on 2024-09-19
2414 Near real-time monitoring of wading birds using uncrewed aircraft systems and computer vision
White, E. P.; Garner, L.; Weinstein, B.; Senyondo, H.; Ortega, A.; Steinkraus, A.; Yenni, G. M.; Frederick, P.; Ernest, S. M.
10.1101/2024.05.14.594154 — ecology — Posted on 2024-09-18
2415 Ensemble Refinement of mismodeled cryo-EM RNA Structures Using All-Atom Simulations
Posani, E.; Janos, P.; Haack, D.; Toor, N.; Bonomi, M.; Magistrato, A.; Bussi, G.
10.1101/2024.07.24.604258 — molecular biology — Posted on 2024-09-18
2419 The within-subject stability of cortical thickness, surface area, and brain volumes across one year
Wang, M.-Y.; Korbmacher, M.; Eikeland, R.; Nerland, S.; Vidal-Pineiro, D.; Specht, K.
10.1101/2024.06.01.596956 — neuroscience — Posted on 2024-09-18
2420 MAPK/ERK signaling in gliomas modulates interferon responses, T cell recruitment, enhances tumor-microglia crosstalk, and drives immune checkpoint blockade efficacy.
Kim, K.-S.; Zhang, J.; Arrieta, V. A.; Dmello, C.; Grabis, E.; Habashy, K.; Duffy, J.; Zhao, J.; Gould, A.; Chen, L.; Hu, J.; Balyasnikova, I.; Chand, D.; Levey, D.; Canoll, P.; Zhao, W.; Sims, P.; Rabadan, R.; Pandey, S.; Zhang, B.; Lee-Chang, C.; Heiland, D. H.; Sonabend, A. M.
10.1101/2024.09.11.612571 — cancer biology — Posted on 2024-09-18
2421 Computationally accelerated identification of P-glycoprotein inhibitors
McCormick, L. A.; McCormick, J. W.; Park, C.; Follit, C. A.; Wise, J. G.; Vogel, P. D.
10.1101/2024.03.05.583428 — cancer biology — Posted on 2024-09-18
2422 Membrane Lipid Nanodomains Modulate HCN Pacemaker Channels in Nociceptor DRG Neurons
Handlin, L. J.; Macchi, N. L.; Dumaire, N.; Salih, L.; Lessie, E. N.; McCommis, K. S.; Moutal, A.; Dai, G.
10.1101/2023.09.02.556056 — biophysics — Posted on 2024-09-18
2424 RNA-dependent RNA polymerase of predominant human norovirus forms liquid-liquid phase condensates as viral replication factories
Kaundal, S.; Ramakrishnan, A.; Ayyar, B. V.; Shanker, S.; Kaur, G.; Crawford, S. E.; Pollet, J.; Stossi, F.; Estes, M. K.; Prasad, B. V. V.
10.1101/2023.08.24.554692 — biochemistry — Posted on 2024-09-18
2426 YTHDF1 Facilitates Lung Adenocarcinoma Progression via Promotion of EEF1G Translation in a m6A-Dependent Manner
Wang, L.; Sheng, Q.; Wang, X.; Yue, H.; Wang, Q.; Zhang, M.; Ma, J.; Wu, L.; Zhang, J.; Cheng, Z.; Yu, W.; Liu, T.; Wang, J.
10.1101/2024.09.13.612607 — cancer biology — Posted on 2024-09-18
2427 metagWGS, a comprehensive workflow to analyze metagenomic data using Illumina or PacBio HiFi reads
Mainguy, J.; Vienne, M.; Fourquet, J.; Darbot, V.; Noirot, C.; Castinel, A.; Combes, S.; Gaspin, C.; Milan, D.; Donnadieu, C.; Iampietro, C.; Bouchez, O.; Pascal, G.; Hoede, C.
10.1101/2024.09.13.612854 — bioinformatics — Posted on 2024-09-18
2428 Enhancing timber traceability via multielement and strontium isotope ratio: An example from the Eastern Alps
Aguzzoni, A.; Giammarchi, F.; Mundo, I. A.; Voto, G.; Tonon, G.; Tirler, W.; Tomelleri, E.
10.1101/2024.09.13.612829 — ecology — Posted on 2024-09-18
2429 The Human Cytomegalovirus vGPCR UL33 is Essential for Efficient Lytic Replication in Epithelial Cells
Freeman, M. R.; Dooley, A. L.; Beucler, M. J.; Sanders, W.; Moorman, N. J.; O'Connor, C. M.; Miller, W. E.
10.1101/2024.09.18.609710 — microbiology — Posted on 2024-09-18
2430 Light-harvesting by antenna-containing rhodopsins in pelagic Asgard archaea
Tzlil, G.; del Carmen Marin, M.; Matsuzaki, Y.; Nag, P.; Itakura, S.; Mizuno, Y.; Murakoshi, S.; Tanaka, T.; Larom, S.; Konno, M.; Abe-Yoshizumi, R.; Molina-Marquez, A.; Barcenas-Perez, D.; Cheel, J.; Koblizek, M.; Leon, R.; Katayama, K.; Kandori, H.; Schapiro, I.; Shihoya, W.; Nureki, O.; Inoue, K.; Rozenberg, A.; Chazan, A.; Beja, O.
10.1101/2024.09.18.613612 — microbiology — Posted on 2024-09-18
2435 Cell-derived matrices mechanics as a functional read-out in Collagen VI-related Congenital Muscular Dystrophies
White, T.; Lopez-Marquez, A.; Badosa, C.; Jimenez-Mallebrera, C.; Samitier, J.; Giannotti, M. I.; Lagunas, A.
10.1101/2024.09.13.612824 — biophysics — Posted on 2024-09-18
2439 U2AF regulates the translation and localization of nuclear-encoded mitochondrial mRNAs
Garcia, G. R.; Palangat, M.; Moraly, J.; Donovan, B. T.; Wang, B.; Phadke, I.; Sturgill, D.; Chen, J.; Short, B.; Rivero, G. A.; Swoboda, D. M.; Taylor, N.; McGraw, K.; Larson, D. R.
10.1101/2024.09.18.613780 — molecular biology — Posted on 2024-09-18
2440 Cutibacterium adaptation to life on humans provides a novel biomarker of C. acnes infections.
Shafiuddin, M.; Prather, G. W.; Huang, W. C.; Anton, J. R.; Martin, A. L.; Sillart, S. B.; Tang, J. Z.; Vittori, M. R.; Prinsen, M. J.; Ninneman, J. J.; Manithody, C.; Henderson, J. P.; Aleem, A. W.; Ilagan, M. X. G.; McCoy, W. H.
10.1101/2024.09.18.613542 — microbiology — Posted on 2024-09-18
2447 A functional screen for ubiquitin regulation identifies an E3 ligase secreted by Pseudomonas aeruginosa
Roberts, C. G.; Kaur, S.; Ogden, A. J.; Divine, M. E.; Warren, G. D.; Kang, D.; Kirienko, N. V.; Geurink, P. P.; Mulder, M. P.; Nakayasu, E. S.; McDermott, J. E.; Adkins, J. N.; Aballay, A.; Pruneda, J. N.
10.1101/2024.09.18.613774 — microbiology — Posted on 2024-09-18
2449 DNA replication dynamics are associated with genome composition in Plasmodium species
Totanes, F. I. G.; Chapman, S. E.; Rai, S. K.; Jones, M.; Boemo, M. A.; Merrick, C. J.
10.1101/2024.09.18.613472 — microbiology — Posted on 2024-09-18
2451 IL-27 neutralization to modulate the tumor microenvironment and increase immune checkpoint immunotherapy efficacy
Papargyris, L.; Glaziou, Q.; Basset, L.; d'Almeida, S.; Pignon, P.; Jabrane-Ferrat, N.; Blanquart, C.; Delneste, Y.; TABIASCO, J.
10.1101/2024.09.13.612803 — immunology — Posted on 2024-09-18
2454 Transcriptional-program-based deciphering of the MET exon 14 skipping regulation network
Truong, M.-J.; Pawlak, G.; Meneboo, J.-P.; Sebda, S.; Fernandes, M.; Figeac, M.; Elati, M.; Tulasne, D.
10.1101/2024.09.13.612820 — cancer biology — Posted on 2024-09-18
2457 Proteomic and N-glycomic comparison of synthetic and bovine whey proteins and their effect on human gut microbiomes
Bolino, M.; Duman, H.; Avci, I.; Kayili, H. M.; Petereit, J.; Zundel, C.; Salih, B.; Karav, S.; Frese, S. A.
10.1101/2024.09.18.613515 — microbiology — Posted on 2024-09-18
2458 Acute Viral Infection Accelerates Neurodegeneration in a Mouse Model of ALS
Marzok, A.; Mapletoft, J. P.; Cowbrough, B.; Celeste, D. B.; D'Agostino, M. R.; Ang, J. C.; Chen, A.; Surendran, V.; Dvorkin-Gheva, A.; Zhang, A.; Kollar, Y.; Stacey, H. D.; Afkhami, S.; Lam, M.; Milnes, K. R.; Miller, M. S.
10.1101/2024.09.17.613525 — immunology — Posted on 2024-09-18
2460 Variant classification guidelines for animals to objectively evaluate genetic variant pathogenicity
Boeykens, F.; Abitbol, M.; Anderson, H.; Casselman, I.; Dufaure de Citres, C.; Hayward, J. J.; Häggström, J.; Kittleson, M. D.; Lepri, E.; Ljungvall, I.; Longeri, M.; Lyons, L. A.; Ohlsson, A.; Peelman, L.; Smets, P.; Vezzosi, T.; van Steenbeek, F.; Broeckx, B. J. G.
10.1101/2024.09.17.613537 — genetics — Posted on 2024-09-18
2465 PANOMIQ: A Unified Approach to Whole-Genome, Exome, and Microbiome Data Analysis
Srivastava, S.; Ehsan, S.; Chowdhury, L.; Faruk, M. O.; Singh, A.; Kapoor, A. S.; Bhinder, S.; Singh, M. P.; Mishra, D.
10.1101/2024.09.17.613203 — bioinformatics — Posted on 2024-09-18
2468 Assessing bnAb potency in the context of HIV-1 Envelope conformational plasticity
Foulkes, C.; Friedrich, N.; Ivan, B.; Stiegeler, E.; Magnus, C.; Schmidt, D.; Karakus, U.; Weber, J.; Günthard, H. F.; Pasin, C.; Rusert, P.; Trkola, A.
10.1101/2024.09.13.612684 — immunology — Posted on 2024-09-18
2469 Stigma longevity is not a major limiting factor in hybrid wheat seed production
Millan-Blanquez, M.; Simmonds, J.; Bird, N.; Manes, Y.; Uauy, C.; Boden, S. A.
10.1101/2024.09.13.612789 — plant biology — Posted on 2024-09-18
2472 From a single sequence to evolutionary trajectories: protein language models capture the evolutionary potential of SARS-CoV-2 protein sequences
Lamb, K. D.; Hughes, J.; Lytras, S.; Young, F.; Koci, O.; Herzig, J.; Lovell, S. C.; Grove, J.; Yuan, K.; Robertson, D. L.
10.1101/2024.07.05.602129 — bioinformatics — Posted on 2024-09-18
2473 Variation in self-compatibility among genotypes and across ontogeny in a self-fertilizing vertebrate
Gresham, J. D.; Earley, R. L.; Clark, A.; Keck, C. M. T.; Longmire, A. E.; Nelson, A. E.; Quertermous, H. M.; White, A. B.
10.1101/2021.02.22.432320 — evolutionary biology — Posted on 2024-09-18
2474 Antibiotics of the future are prone to resistance in Gram-negative pathogens
Daruka, L.; Czikkely, M. S.; Szili, P.; Farkas, Z.; Balogh, D.; Grezal, G.; Maharramov, E.; Vu, T.-H.; Sipos, L.; Juhasz, S.; Dunai, A.; Daraba, A.; Szamel, M.; Sari, T.; Stirling, T.; Vasarhelyi, B. M.; Ari, E.; Christodoulou, C.; Manczinger, M.; Enyedi, M. Z.; Jaksa, G.; Kovacs, K.; van Houte, S.; Pursey, E.; Pinter, L.; Haracska, L.; Kintses, B.; Papp, B.; Pal, C.
10.1101/2023.07.23.550022 — microbiology — Posted on 2024-09-18
2477 Ex-vivo mouse precision cut tumour slices for modelling hepatocellular carcinoma; A 3Rs solution for at-scale drug screening
Collins, A. L.; Kirkness, K.; Ramon-Gil, E.; Tzortzopoulou, E.; Geh, D.; Cameron, R.; Luli, S.; Khurram, E.; Storey, D.; Paish, H.; McDonald, D.; Filby, A.; Borthwick, L. A.; Oakley, F.; Mann, D.; Leslie, J.
10.1101/2024.09.16.613213 — cancer biology — Posted on 2024-09-18
2479 Proteomic and Lipidomic Plasma Evaluations Reveal Biomarkers for Domoic Acid Toxicosis in California Sea Lions
Solosky, A. M.; Claudio, I. M.; Chappel, J. R.; Kirkwood-Donelson, K. I.; Janech, M. G.; Bland, A. M.; Gulland, F.; Neely, B. A.; Baker, E.
10.1101/2024.05.06.592757 — bioinformatics — Posted on 2024-09-18
2480 A double-ring of human RAD52 remodels replication forks restricting fork reversal
Honda, M.; Razzaghi, M.; Gaur, P.; Malacaria, E.; Marozzi, G.; Di Biagi, L.; Aiello, F. A.; Paintsil, E. A.; Stanfield, A.; Deppe, B. J.; Gakhar, L.; Schnicker, N. J.; Spies, M. A.; Pichierri, P.; Spies, M.
10.1101/2023.11.14.566657 — biochemistry — Posted on 2024-09-18
2481 Destabilisation of bam transcripts terminates the mitotic phase of Drosophila female germline differentiation
Samuels, T. J.; Torley, E. J.; Naden, E. L.; Blair, P. E.; Hernandez Frometa, F. A.; Karam Teixeira, F.
10.1101/2024.07.24.604138 — developmental biology — Posted on 2024-09-18
2484 From Monomers to Oligomers: Structural Mechanism of Receptor-Triggered MyD88 Assembly in Innate Immune Signaling
Kasai, K.; Imamura, K.; Uno, M.; Sekiyama, N.; Miyata, T.; Makino, F.; Yamada, R.; Takahashi, Y.; Kodera, N.; Namba, K.; Ohnishi, H.; Narita, A.; Konno, H.; Tochio, H.
10.1101/2024.09.13.612588 — biophysics — Posted on 2024-09-18
2486 A regulatory module driving the recurrent evolution of irreducible molecular complexes.
Tikanova, P.; Ross, J. J.; Hagmueller, A.; Puehringer, F.; Pliota, P.; Krogull, D.; Stefania, V.; Hunold, M.; Koreshova, A.; Koller, A.; Ostapchuk, I.; Okweri, J.; Gokcezade, J.; Duchek, P.; Dong, G.; Ben-David, E.; Burga, A.
10.1101/2024.09.16.613340 — genomics — Posted on 2024-09-18
2487 The Drosophila maternal-effect gene abnormal oocyte (ao) does not repress histone gene expression
Takenaka, R.; Simmerman, S. M.; Schmidt, C. A.; Albanese, E. H.; Rieder, L. E.; Malik, H. S.
10.1101/2024.09.17.613536 — genetics — Posted on 2024-09-18
2489 Cholesterol binding to VCAM-1 promotes vascular inflammation
Kennelly, J. P.; Xiao, X.; Gao, Y.; Kim, S.; Hong, S.-G.; Villanueva, M.; Ferrari, A.; Vanharanta, L.; Nguyen, A.; Nagari, R. T.; Burton, N. R.; Tol, M. J.; Becker, A. P.; Lee, M. J.; Ikonen, E.; Backus, K.; Mack, J. J.; Tontonoz, P.
10.1101/2024.09.17.613543 — physiology — Posted on 2024-09-18
2490 Endothelial miR-34a deletion guards against aneurysm development despite endothelial dysfunction
Grochot-Przeczek, A.; Kopacz, A.; Kloska, D.; Bar, A.; Targosz-Korecka, M.; Cysewski, D.; Chlopicki, S.; Jozkowicz, A.
10.1101/2024.09.12.612788 — pathology — Posted on 2024-09-18
2492 Identification of potent biparatopic antibodies targeting FGFR2 fusion driven cholangiocarcinoma.
Chaturantabut, S.; Oliver, S.; Frederick, D. T.; Kim, J.; Robinson, F. P.; Sinopoli, A.; Song, T.-Y.; Rodriguez, D. J.; Chang, L.; Kesar, D.; He, Y.; Ching, M.; Dzvurumi, R.; Atari, A.; Tseng, Y.-Y.; Bardeesy, N.; Sellers, W. R.
10.1101/2024.09.16.613045 — cancer biology — Posted on 2024-09-18
2493 Integrative multiomic approaches reveal ZMAT3 and p21 as conserved hubs in the p53 tumor suppression network
Boutelle, A. M.; Mabene, A. R.; Yao, D.; Xu, H.; Wang, M.; Tang, Y. J.; Lopez, S. S.; Sinha, S.; Demeter, J.; Cheng, R.; Benard, B. A.; Valente, L. J.; Drainas, A. P.; Fischer, M. D.; Majeti, R.; Petrov, D.; Jackson, P. K.; Yang, F.; Winslow, M. M.; Bassik, M. C.; Attardi, L. D.
10.1101/2024.09.17.612743 — cancer biology — Posted on 2024-09-18
2494 A combined approach to extract rotational dynamics of globular proteins undergoing liquid-liquid phase separation
Gendreizig, D.; Kalarikkal, A.; Holtbrügge, S. L.; Mukherjee, S.; Galazzo, L.; Kucher, S.; Rosspeintner, A.; Schäfer, L. V.; Bordignon, E.
10.1101/2024.09.17.613388 — biophysics — Posted on 2024-09-18
2496 The "very moment" when UDG recognizes aflipped-out uracil base in dsDNA
Saravanan, V.; Raouraoua, N.; Brysbaert, G.; Giordano, S.; Lensink, M. F.; Cleri, F.; Blossey, R.
10.1101/2024.09.13.612628 — bioinformatics — Posted on 2024-09-18
2498 Engineered Receptors for Soluble Cell-to-Cell Communication
Piraner, D. I.; Abedi, M. H.; Duran Gonzalez, M. J.; Chazin-Gray, A.; Zhu, I.; Ravindran, P. T.; Schlichthaerle, T.; Huang, B.; Lee, D.; Baker, D.; Roybal, K. T.
10.1101/2024.09.17.613377 — bioengineering — Posted on 2024-09-18
2499 A microinjection protocol for the greater waxworm moth, Galleria mellonella
Pearce, J. C.; Housden, A.; Senior, N. J.; Champion, O. L.; Prior, J. L.; Titball, R. W.; Wakefield, J. G.
10.1101/2024.09.17.613528 — bioengineering — Posted on 2024-09-18
2500 Mechanistic studies of mycobacterial glycolipid biosynthesis by the mannosyltransferase PimE
Liu, Y.; Brown, C. M.; Borges, N.; Nobre, R. N.; Erramilli, S.; Dufrisne, M. B.; Kloss, B.; Giacometti, S.; Esteves, A. M.; Timoteo, C. G.; Tokarz, P.; Cater, R.; Morita, Y. S.; Kossiakoff, A. A.; Santos, H.; Stansfeld, P. J.; Nygaard, R.; Mancia, F.
10.1101/2024.09.17.613550 — biochemistry — Posted on 2024-09-18
2501 Structural insights into terminal arabinosylation biosynthesis of the mycobacterial cell wall arabinan
Liu, Y.; Brown, C. M.; Erramilli, S.; Su, Y.-C.; Tseng, P.-S.; Wang, Y.-J.; Duong, N. H.; Tokarz, P.; Kloss, B.; Han, C.-R.; Chen, H.-Y.; Rodrigues, J.; Archer, M.; Lowary, T. L.; Kossiakoff, A. A.; Stansfeld, P. J.; Nygaard, R.; Mancia, F.
10.1101/2024.09.17.613533 — biochemistry — Posted on 2024-09-18
2504 Targeting the untargeted: Uncovering the chemical complexity of root exudates
Moeller, K.; Ritter, A.; Stobinsky, P.; Jensen, K.; Meier, I. C.; Subrahmaniam, H. J.
10.1101/2024.09.17.613458 — ecology — Posted on 2024-09-18
2507 Towards Longitudinal Characterization of Multiple Sclerosis Atrophy Employing SynthSeg Framework and Normative Modeling
Gordaliza, P. M.; Molchanova, N.; Wynen, M.; Maggi, P.; Janssen, J.; Banus, J.; Cagol, A.; Granziera, C.; Bach Cuadra, M.
10.1101/2024.09.17.613272 — neuroscience — Posted on 2024-09-18
2510 Merkel cell carcinoma-derived macrophage migration inhibitory factor (MIF) may promote persistence of Chronic Lymphocytic Leukemia
Alencar, G. F.; Rodriguez, H. J.; Pulliam, T. H.; Remington, A. J.; Gilmour, M. W.; Alam, R.; Jabbour, A. J.; Mullen, L. J.; DeBuysscher, B. L.; Nghiem, P.; Taylor, J. J.
10.1101/2024.09.09.611517 — cancer biology — Posted on 2024-09-18
2511 Unlocking precision: How corneal cell area analysis revolutionises post-transplant stem cell monitoring
Parkinson, P.; Makarenko, I.; Baylis, O. J.; Figueiredo, G. S.; Lako, M.; Shukurov, A.; Figueiredo, F. C.; Wadkin, L. E.
10.1101/2024.09.17.612429 — biophysics — Posted on 2024-09-18
2512 Pangenomics to understand prophage dynamics in the Pectobacterium genus and the radiating lineages of P. brasiliense
Pardeshi, L. A.; van Duivenbode, I.; Pel, M. J. C.; Jonkheer, E. M.; Kupczok, A.; de Ridder, D.; Smit, S.; van der Lee, T.
10.1101/2024.09.02.610764 — bioinformatics — Posted on 2024-09-18
2514 Afterload-induced Decreases in Fatty Acid Oxidation Develop Independently of Increased Glucose Utilization
Piristine, H.; May, H. I.; Jiang, N.; Daou, D.; Olivares-Silva, F.; Elnwasany, A.; Szweda, P.; Kinter, C.; Kinter, M.; Sharma, G.; Wen, X.; Malloy, C. R.; Jessen, M. E.; Gillette, T. G.; Hill, J. A.
10.1101/2024.09.17.613531 — cell biology — Posted on 2024-09-18
2515 Reducing oxidative stress improves ex vivo polymer-based human haematopoietic stem and progenitor cell culture and gene editing
Bozhilov, Y.; Brown, E.; Hsu, I.; Singh, I.; Rodriguez-Fraticelli, A.; Roy, A.; Yamazaki, S.; Wilkinson, A. C.
10.1101/2024.09.17.613552 — cell biology — Posted on 2024-09-18
2517 IL-13 promotes sensory-sympathetic neurons crosstalk in asthma
Crosson, T.; Bhat, S.; Wang, J.-C.; Salaün, C.; Roversi, K.; Herzog, H.; Rafei, M.; Blunck, R.; Talbot, S.
10.1101/2023.01.26.525731 — neuroscience — Posted on 2024-09-18
2520 The lysosomal membrane protein LAMP2B mediates microlipophagy to target obesity-related disorders
Sakai, R.; Aizawa, S.; Lee-Okada, H.-C.; Hase, K.; Fujita, H.; Kikuchi, H.; U. Inoue, Y.; Inoue, T.; Kabuta, C.; Yokomizo, T.; Hashimoto, T.; Wada, K.; Mano, T.; Koyama-Honda, I.; Kabuta, T.
10.1101/2024.09.18.613587 — cell biology — Posted on 2024-09-18
2521 Detailed Colocalization Analysis of A- and B-type Nuclear Lamins: a Workflow Using Super-Resolution STED Microscopy and Deconvolution
Stiekema, M.; Gibson, O. N.; Veltrop, R. J. A.; Ramaekers, F. C. S.; Broers, J. L. V.; Zandvoort, M. A. M. J. v.
10.1101/2024.09.17.613415 — cell biology — Posted on 2024-09-18
2523 Seipin Regulates Caveolin-1 Trafficking and Organelle Crosstalk
Carpentier, M.; Omrane, M.; Trager, J.; Zouiouich, M.; Shaaban, R.; Prieur, X.; Palard, M.; El Khallouki, N.; Giordano, F.; Harayama, T.; Vigouroux, C.; Le Lay, S.; THIAM, A. R.
10.1101/2024.09.17.613438 — cell biology — Posted on 2024-09-18
2524 Type-II kinase inhibitors that target Parkinson's Disease-associated LRRK2
Raig, N. D.; Surridge, K. J.; Sanz-Murillo, M.; Dederer, V.; Kramer, A.; Schwalm, M. P.; Elson, L.; Chatterjee, D.; Mathea, S.; Hanke, T.; Leschziner, A. E.; Reck-Peterson, S. L.; Knapp, S.
10.1101/2024.09.17.613365 — cell biology — Posted on 2024-09-18
2525 Select autosomal dominant DFNA11 deafness mutations activate Myo7A in epithelial cells
Acharya, P.; Thapa, G.; Liao, X.; Matoo, S.; Graves, M. J.; Atallah, S. Y.; Tipirneni, A. K.; Nguyen, T.; Chhabra, N. M.; Maschack, J.; Herod, M. R.; Ohaezu, F.; Robison, A.; Mudaliyar, A.; Bharaj, J.; Roeser, N.; Holmes, K.; Nayak, V.; Alsayed, R.; Perrin, B. J.; Crawley, S. W.
10.1101/2024.09.17.613491 — cell biology — Posted on 2024-09-18
2526 A Red Fluorescent Lifeact Marker to Study Actin Morphology in Podocytes
Wiesner, E.; Binz-Lotter, J.; Troeder, S. E.; Unnersjoe-Jess, D.; Rutkowski, N.; Zevnik, B.; Benzing, T.; Wedlich-Soldner, R.; Hackl, M. J.
10.1101/2024.09.17.613449 — cell biology — Posted on 2024-09-18
2527 An extensive archaeological dental calculus dataset spanning 5000 years for ancient human oral microbiome research
Standeven, F. J.; Dahlquist-Axe, G.; Hendy, J.; Fiddyment, S.; Holst, M.; McGrath, K.; Collins, M.; Mundorff, A.; Meehan, C. J.; Tedder, A.; Speller, C. F.
10.1101/2024.09.17.613443 — microbiology — Posted on 2024-09-18
2528 Epigenetic control of tetrapyrrole biosynthesis by m4C DNA methylation in a cyanobacterium
Schmidt, N.; Stappert, N.; Nimura-Matsune, K.; Watanabe, S.; Sobotka, R.; Hagemann, M.; Hess, W. R.
10.1101/2024.08.20.608618 — microbiology — Posted on 2024-09-18
2532 Unisensory visual and auditory objects are processed in olfactory cortex, independently of odor association
Thunell, E.; Peter, M. G.; Iravani, B.; Porada, D. K.; Prenner, K.; Darki, F.; Lundstrom, J. N.
10.1101/2023.04.20.537709 — neuroscience — Posted on 2024-09-18
2534 Cellular Dynamics Upon Immune Checkpoint Inhibition
Lin, Z.; Petrenko, E.; Chandra, M.; Srinivas, N.; Ugurel, S.; Becker, J.; Aran, D.
10.1101/2024.06.30.601413 — cancer biology — Posted on 2024-09-18
2535 An Iterative Approach to Polish the Nanopore Sequencing Basecalling for Therapeutic RNA Quality Control
Wang, Z.; Tu, M.-J.; Liu, Z.; Wang, K. K.; Fang, Y.; Hao, N.; Zhang, H. H.; Que, J.; Sun, X.; Yu, A.-M.; DING, H.
10.1101/2024.09.12.612711 — bioinformatics — Posted on 2024-09-18
2537 ANASFV: a workflow for ASFV whole genome sequencing, assembly, and evaluation
Li, K.; Han, X.; Shao, Y.; Zhang, Y.; Zhao, X.; Johnson, E. W.; Li, R.
10.1101/2024.07.08.602471 — genetics — Posted on 2024-09-18
2539 LncRNA TAAL is a Modulator of Tie1-Mediated Vascular Function in Diabetic Retinopathy
Ranjan, G.; Arora, S.; Sharma, S.; Sharma, L.; Bhoyar, R. C.; Senthivel, V.; Scaria, V.; Chakrabarti, S.; Kaur, I.; Sivasubbu, S.; Motiani, R. K.
10.1101/2024.09.13.612383 — genetics — Posted on 2024-09-18
2540 Avoidable false PSMC population size peaks occur across numerous studies
Hilgers, L.; Liu, S.; Jensen, A.; Brown, T.; Cousins, T.; Schweiger, R.; Guschanski, K.; Hiller, M.
10.1101/2024.06.17.599025 — evolutionary biology — Posted on 2024-09-18
2544 Medin Induces Pro-Inflammatory Activation of Human Brain Vascular Smooth Muscle Cells
Karamanova, N.; Morrow, K. T.; Maerivoet, A.; Madine, J.; Li, M.; Migrino, R. Q.
10.1101/2024.09.16.613366 — molecular biology — Posted on 2024-09-18
2545 Comparative Characterization of Bronchial and Nasal Mucus Reveals Key Determinants of Influenza A Virus Inhibition
Pohl, M. O.; Violaki, K.; Liu, L.; Gaggioli, E.; Glas, I.; von Kempis, J.; Lin, C.-w.; Terrettaz, C.; David, S. C.; Charlton, F.; Motos, G.; Bluvshtein, N.; Schaub, A.; Klein, L. K.; Luo, B.; Hugentobler, W.; Krieger, U. K.; Peter, T.; Kohn, T.; Nenes, A.; Stertz, S.
10.1101/2024.09.17.613498 — microbiology — Posted on 2024-09-18
2546 Group-common and individual-specific effects of structure-function coupling in human brain networks with graph neural networks
Chen, P.; Yang, H.; Zheng, X.; Jia, H.; Hao, J.; Xu, X.; Li, C.; He, X.; Chen, R.; Okubo, T. S.; Cui, Z.
10.1101/2023.11.22.568257 — neuroscience — Posted on 2024-09-18
2549 MAPK/ERK signaling in gliomas modulates interferon responses, T cell recruitment, enhances tumor-microglia crosstalk, and drives immune checkpoint blockade efficacy.
Kim, K.-S.; Zhang, J.; Arrieta, V. A.; Dmello, C.; Grabis, E.; Habashy, K.; Duffy, J.; Zhao, J.; Gould, A.; Chen, L.; Hu, J.; Balyasnikova, I.; Chand, D.; Levey, D.; Canoll, P.; Zhao, W.; Sims, P.; Rabadan, R.; Pandey, S.; Zhang, B.; Lee-Chang, C.; Heiland, D. H.; Sonabend, A. M.
10.1101/2024.09.11.612571 — cancer biology — Posted on 2024-09-18
2550 Visualizing PIEZO1 Localization and Activity in hiPSC-Derived Single Cells and Organoids with HaloTag Technology
Bertaccini, G. A.; Casanellas, I.; Evans, E. L.; Nourse, J. L.; Dickinson, G. D.; Liu, G.; Seal, S.; Ly, A. T.; Holt, J. R.; Wijerathne, T. D.; Yan, S.; Hui, E. E.; Lacroix, J. J.; Panicker, M. M.; Upadhyayula, S.; Parker, I.; Pathak, M. M.
10.1101/2023.12.22.573117 — biophysics — Posted on 2024-09-18
2551 Distinct and interdependent functions of three RING proteins regulate recombination during mammalian meiosis
Ito, M.; Yun, Y.; Kulkarni, D. S.; Sandhu, S.; Nunez, B.; Hu, L.; Lee, K.; Lim, N.; Hirota, R.; Prendergast, R.; Huang, C.; Huang, I.; Hunter, N.
10.1101/2023.11.07.566091 — genetics — Posted on 2024-09-18
2552 Variation in spatial population structure in the Anopheles gambiae species complex
McCann, R. S.; Courneya, J.-P.; Donnelly, M.; Laufer, M. K.; Mzilahowa, T.; Stewart, K.; Agossa, F.; Tezzo, F. W.; Miles, A.; Takala-Harrison, S.; O'Connor, T. D.; Ag1000G Consortium,
10.1101/2024.05.26.595955 — ecology — Posted on 2024-09-18
2554 Tick extracellular vesicles undermine epidermal wound healing during hematophagy
Marnin, L.; Valencia, L.; Bogale, H.; Laukaitis-Yousey, H.; Rolandelli, A.; Ferraz, C. R.; O'Neal, A. J.; Schmitter-Sanchez, A.; Bencosme Cuevas, E.; Nguyen, T.-T.; Leal-Galvan, B.; Rickert, D.; Mendes, M. T.; Samaddar, S.; Butler, L. R.; Singh, N.; Cabrera Paz, F.; Oliver, J.; Jameson, J.; Munderloh, U.; Oliva Chavez, A.; Mulenga, A.; Park, S.; Serre, D.; Pedra, J. H. F.
10.1101/2023.11.10.566612 — microbiology — Posted on 2024-09-18
2556 A simple framework for agent-based modeling with extracellular matrix
Metzcar, J.; Duggan, B. S.; Fischer, B.; Murphy, M.; Heiland, R.; Macklin, P.
10.1101/2022.11.21.514608 — systems biology — Posted on 2024-09-18
2558 Vesicular and non-vesicular extracellular small RNAs direct gene silencing in a plant-interacting bacterium
RAVET, A.; Zervudacki, J.; SINGLA-RASTOGI, M.; CHARVIN, M.; Thiebeauld, O.; Perez-Quintero, A. L.; Courgeon, L.; Candat, A.; Lebeau, L.; EMIDIO-FORTUNATO, A.; MENDU, V.; NAVARRO, L.
10.1101/863902 — plant biology — Posted on 2024-09-18
2564 Species limits and hybridization in Andean leaf-eared mice (Phyllotis)
Quiroga-Carmona, M.; Liphardt, S.; Bautista, N. M.; Jayat, P.; Teta, P.; Malaney, J. L.; McFarland, T.; Cook, J. A.; Blumer, M.; Herrera, N. D.; Cheviron, Z. A.; Good, J.; D'Elia, G.; Storz, J.
10.1101/2024.08.31.610610 — evolutionary biology — Posted on 2024-09-18
2565 Multi-Omics Atlas-Assisted Discovery of Transcription Factors for Selective T Cell State Programming
Chung, H. K.; Liu, C.; Jambor, A. N.; Riesenberg, B. P.; Sun, M.; Casillas, E.; Chen, T.; Chick, B.; Wang, J.; Mcdonald, B.; Wang, J.; He, P.; Yang, Q.; Varanasi, S. K.; Mann, T.; Chen, D.; Hoffmann, F.; Tripple, V.; Hang, Y.; Ho, J.; Cho, U. H.; Williams, A.; Wang, Y.; Hargreaves, D.; Thaxton, J. E.; Kaech, S. M.; Wang, W.
10.1101/2023.01.03.522354 — immunology — Posted on 2024-09-18
2570 Off-Equilibrium Fluctuation-Dissipation Theorem Paves the Way in Alzheimer's Disease Research
Patow, G. A.; Monti, J. M.; Acero-Pous, I.; Idesis, S.; Escrichs, A.; Perl, Y. S.; Ritter, P.; Kringelbach, M. L.; Deco, G.
10.1101/2024.09.15.613131 — neuroscience — Posted on 2024-09-18
2572 Learning on a Limb: An outreach module to engage high school students in orthopaedics
Panebianco, C. J.; Azar, T.; Duffy, M. P.; Nijsure, M. P.; Sharp, E.; Tamburro, M. K.; Hast, M. W.; Shore, E. M.; Mauck, R.; Soslowsky, L. J.; Shuda, J. R.; Gullbrand, S. E.
10.1101/2024.09.16.612729 — scientific communication and education — Posted on 2024-09-18
2575 Conserved Evolutionary Response to Whole Genome Duplication in Angiosperms Revealed Using High Resolution Gene Expression Profiling
Leal, J. L.; Hodkova, E.; Billhardt, A.; Eklund, D. M.; Granath, G.; Herrera Egoavil, P.; Chen, J.; Milesi, P.; Salojärvi, J.; Lascoux, M.
10.1101/2024.09.12.612700 — evolutionary biology — Posted on 2024-09-17
2576 Decoding polyubiquitin regulation of KV7. 1 functional expression with engineered linkage-selective deubiquitinases
Shanmugam, S. K.; Kanner, S. A.; Zou, X. M.; Amarh, E.; Choudhury, P.; SONI, R.; Kass, R. S.; Colecraft, H. M.
10.1101/2024.09.17.613539 — molecular biology — Posted on 2024-09-17
2577 Reversible excision of the wzy locus in Salmonella Typhimurium may aid recovery following phage predation
Charity, O. J.; Thilliez, G.; Al-Khanaq, H.; Acton, L.; Kolenda, R.; Bawn, M.; Petrovska, L.; Kingsley, R. A.
10.1101/2024.09.17.613263 — microbiology — Posted on 2024-09-17
2578 Implementation of Ribo-BiFC method to plant systems using a split mVenus approach
Raabe, K.; Naprstkova, A.; Pieters, J.; Torutaeva, E.; Jiraskova, V.; Kahrizi, Z.; Michailidis, C.; Honys, D.
10.1101/2024.09.12.612679 — plant biology — Posted on 2024-09-17
2580 Machine-learning convergent melanocytic morphology despite noisy archival slides
Tada, M.; Gaskins, G.; Ghandian, S.; Mew, N.; Keiser, M. J.; Keiser, E. S.
10.1101/2024.09.12.612732 — pathology — Posted on 2024-09-17
2581 The Precise Basecalling of Short-Read Nanopore Sequencing
Wang, Z.; Tu, M.-J.; Song, C.; Liu, Z.; Wang, K. K.; Chen, S.; Yu, A.-M.; DING, H.
10.1101/2024.09.12.612746 — bioinformatics — Posted on 2024-09-17
2582 CRAK-Velo: Chromatin Accessibility Kinetics integration improves RNA Velocity estimation
El Kazwini, N.; Gao, M.; Boudjelthia, I. K.; Cai, F.; Huang, Y.; Sanguinetti, G.
10.1101/2024.09.12.612736 — bioinformatics — Posted on 2024-09-17
2583 Precision Repair of Zone-Specific Meniscal Injuries Using a Tunable Extracellular Matrix-Based Hydrogel System
Lee, S.-H.; Li, Z.; Zhang, E. Y.; Kim, D. H.; Huang, Z.; Lee, S. J.; Kang, H.-W.; Burdick, J. A.; Mauck, R. L.; Heo, S. C.
10.1101/2024.09.12.612723 — bioengineering — Posted on 2024-09-17
2585 The genetic history of Portugal over the past 5,000 years
Roca-Rada, X.; Davidson, R.; Williams, M. P.; Ravishankar, S.; Collen, E.; Haarkotter, C.; Taufik, L.; Carvalho, A. F.; Villalba-Mouco, V.; Cuesta-Aguirre, D. R.; Tente, C.; Calleja, A. M. M.; MacRoberts, R. A.; Melo, L.; Purnomo, G. A.; Souilmi, Y.; Tobler, R.; Cunha, E.; Tereso, S.; Matos, V. M. J.; Fernandes, T. M.; Mauer, A.-F.; Silva, A. M.; Carvalho, P. C.; Llamas, B.; Teixeira, J. C.
10.1101/2024.09.12.612544 — genomics — Posted on 2024-09-17
2588 Assessing Ebola Virus Circulation in the Tshuapa Province (Democratic Republic of the Congo): A One Health Investigation of Wildlife and Human Interactions
van Vredendaal, R.; Joffrin, L.; Paviotti, A.; Mande, C.; Milolo, S.; Laurent, N.; Fourchault, L.; Adroabadrio, D.; Baelo, P.; Ngoy, S.; Ansobi, P.; Nebesse, C.; Peeters, M.; Ayouba, A.; Champagne, M.; Bouillin, J.; Tesikova, J.; Van Houtte, N.; Gryseels, S.; Salloum, M.; Bikioli, F.; Thys, S.; Mpato, J.; Ilonga, R.; Kimina, H.; Lariviere, Y.; Lemey, G.; Van Damme, P.; Van Geertruyden, J.-P.; Muhindo-Mavoko, H.; Mitashi, P.; Leirs, H.; Verheyen, E.; Gembu, G.-C.; Mariën, J.
10.1101/2024.09.17.613482 — molecular biology — Posted on 2024-09-17
2590 Enhancing lysosome function via mTOR/TFEB activation reduces lipofuscin-like granules in early Age-related Macular Degeneration
Falcao, A. S.; Lopes da Silva, M.; Antas, P.; Escrevente, C.; Pedro, M.; Coelho, R.; Ferreira, I. S.; Santos, I. P.; Ciossek, T. C.; Nicklin, P.; Tenreiro, S.; Seabra, M. C.
10.1101/2024.09.17.613413 — molecular biology — Posted on 2024-09-17
2591 Targeting FUS-ALS aggregation with Proteasome Inhibitors
Younis, A.; Yassen, K.; Rozales, K.; Kadah, T.; Saida, N.; Meller, A.; Dutta Hazra, J.; Heinrich, R.; Levy-Adam, F.; Berlin, S.; Shalgi, R.
10.1101/2024.09.17.613412 — molecular biology — Posted on 2024-09-17
2592 Structural insight into the nuclear transportation mechanism of PPARg by Transportin-1
TOMA-FUKAI, S.; Nakamura, Y.; Kawamoto, A.; Shimizu, H.; Hayama, K.; Kojima, R.; Yoshimura, K.; Ishii, M.; Hirose, M.; Teratani, T.; Ohata, S.; Kato, T.; Kamikubo, H.; Itoh, T.; Tomita, K.; Shimizu, T.
10.1101/2024.09.17.612794 — molecular biology — Posted on 2024-09-17
2594 Title Longitudinal Observational (single cohort) Study on the Causes of Trypanocide Failure in cases of African Animal Trypanosomosis in Cattle Near Wildlife Protected Areas of Northern Tanzania
Richards, S.; Pagnossin, D.; Buyugu, P. S.; Manangwa, O.; Mramba, F.; Sindoya, E.; Paxton, E.; Torr, S. J.; Ritchie, R.; Rossi, G. E.; Anyanwu, L. N.; Barrett, M.; Morrison, L. J.; Auty, H.
10.1101/2024.09.17.613397 — microbiology — Posted on 2024-09-17
2596 Extensive PFAS accumulation by human gut bacteria
Lindell, A. E.; Griesshammer, A.; Michaelis, L.; Papagiannidis, D.; Ochner, H.; Kamrad, S.; Guan, R.; Blasche, S.; Ventimiglia, L.; Ramachandran, B.; Ozgur, H.; Zelezniak, A.; Beristain-Covarrubias, N.; Yam-Puc, J. C.; Roux, I.; Barron, L. P.; Richardson, A. K.; Martin, M. G.; Benes, V.; Morone, N.; Thaventhiran, J.; Bharat, T. A. M.; Savitski, M.; Maier, L.; Patil, K. R.
10.1101/2024.09.17.613493 — microbiology — Posted on 2024-09-17
2598 Genomic Analysis of Human-infecting Leptospira borgpetersenii isolates in Sri Lanka expanded PF07598 gene family repertoire, less overall genome reduction than bovine isolates
Senavirathna, I.; Jayasundara, D.; Warnasekara, J.; Agampodi, S. B.; Putz, E. J.; Nally, J. E.; Bayles, D. O.; Chaurasia, R.; Vinetz, J. M.
10.1101/2024.09.17.613401 — microbiology — Posted on 2024-09-17
2599 An extensive archaeological dental calculus dataset spanning 5000 years for ancient human oral microbiome research
Standeven, F. J.; Dahlquist-Axe, G.; Hendy, J.; Fiddyment, S.; Holst, M.; McGrath, K.; Collins, M.; Mundorff, A.; Meehan, C. J.; Tedder, A.; Speller, C. F.
10.1101/2024.09.17.613443 — microbiology — Posted on 2024-09-17
2600 Intravital imaging of pulmonary lymphatics in inflammation and metastatic cancer
Cleary, S. J.; Qiu, L.; Seo, Y.; Baluk, P.; Liu, D.; Serwas, N. K.; Cyster, J. G.; McDonald, D. M.; Krummel, M. F.; Looney, M. R.
10.1101/2024.09.12.612619 — immunology — Posted on 2024-09-17
2602 High-efficiency transformation and gene expression in Picosynechococcus sp. PCC 7002
Hren, A. P.; Abraham, J. P.; Tumen-Velasquez, M. P.; Vergara, M. M.; Guss, A. M.; Alexander, W. G.; Pfleger, B. F.; Fox, J. M.; Eckert, C. A.
10.1101/2024.09.17.613521 — synthetic biology — Posted on 2024-09-17
2603 A modular system for programming multistep activation of endogenous genes in stem cells
Puppala, A. K.; Nielsen, A. C.; Regan, M. R.; Mancinelli, G. E.; DePooter, R. F.; Arnovitz, S.; Harding, C.; McGregor, M.; Balanis, N. G.; Clarke, R.; Merrill, B. J.
10.1101/2024.09.17.613466 — synthetic biology — Posted on 2024-09-17
2605 PangeBlocks: customized construction of pangenome graphs via maximal blocks
Bonizzoni, P.; Avila Cartes, J. E.; Ciccolella, S.; Della Vedova, G.; Denti, L.
10.1101/2024.09.17.613426 — bioinformatics — Posted on 2024-09-17
2607 MPXV Infects Human PBMCs in a Type I Interferon-Sensitive Manner
Bosquillon de Jarcy, L.; Postmus, D.; Jansen, J.; Melchert, J.; Hoffmann, D.; Corman, V. M.; Goffinet, C.
10.1101/2024.09.16.613292 — immunology — Posted on 2024-09-17
2611 Limbic System White Matter in Children and Adolescents with ADHD: A Longitudinal Diffusion MRI Analysis
Connaughton, M.; Leemans, A.; Silk, T. J.; Anderson, V.; OHanlon, E.; Whelan, R.; McGrath, J.
10.1101/2024.09.17.613410 — neuroscience — Posted on 2024-09-17
2616 Notch/Hairless Pathway Modulation of sog Transcriptional Bursting in Prelude to Gastrulation
Fenelon, K. D.; Borad, P.; Rout, B.; Boodaghimalidarreh, P.; Nasr, M. S.; Luber, J.; Koromila, T.
10.1101/2024.09.17.613495 — developmental biology — Posted on 2024-09-17
2617 Overabundant endocannabinoids in neurons are detrimental to cognitive function
Zhu, D.; Zhang, J.; Ma, X.; Hu, M.; Gao, F.; Hashem, J.; Lyu, J.; Wei, J.; Cui, Y.; Qiu, S.; Chen, C.
10.1101/2024.09.17.613513 — neuroscience — Posted on 2024-09-17
2620 Astrocyte glucocorticoid receptors mediate sex-specific changes in activity following stress
Depaauw-Holt, L.; Hamane, S.; Peyrard, S.; Rogers, B.; Fulton, S.; Bosson, A.; Murphy-Royal, C.
10.1101/2024.09.17.613499 — neuroscience — Posted on 2024-09-17
2622 Amygdala stimulation transforms short-term memory into remote memory by persistent activation of atypical PKC in the anterior cingulate cortex
Almaguer-Melian, W.; Merceron-Martinez, D.; Alacan-Ricardo, L.; Pina, A. B.; Hsieh, C.; Bergado-Rosado, J. A.; Sacktor, T. C.
10.1101/2024.09.17.613040 — neuroscience — Posted on 2024-09-17
2624 Comparison of Explainable AI Models for MRI-based Alzheimer's Disease Classification
Chattopadhyay, T.; Joshy, N. A.; Jagad, C.; Gleave, E.; Thomopoulos, S. I.; Feng, Y.; Villalon-Reina, J. E.; Laltoo, E.; Joshi, H.; Venkatasubramanian, G.; John, J. P.; Steeg, G. V.; Ambite, J. L.; Thompson, P. M.
10.1101/2024.09.17.613560 — neuroscience — Posted on 2024-09-17
2625 Sex-specific maladaptive responses to acute stress upon in utero THC exposure are mediated by dopamine
Serra, V.; Traccis, F.; Aroni, S.; Vidal Palencia, L.; Concas, L.; Serra, M.; Leone, R.; Porcu, P.; Busquets-Garcia, A.; Frau, R.; Melis, M.
10.1101/2024.09.17.613444 — neuroscience — Posted on 2024-09-17
2626 Neuroimaging model of visceral manipulation in awake rat
Cramer, S. R.; Han, X.; Chan, D. C. Y.; Neuberger, T.; Zhang, N.
10.1101/2024.09.17.613477 — neuroscience — Posted on 2024-09-17
2628 A dopaminergic basis of behavioral control
Ballard, I. C.; Furman, D. J.; Berry, A. S.; White, R. L.; Jagust, W. J.; Kayser, A. S.; D'Esposito, M.
10.1101/2024.09.17.613524 — neuroscience — Posted on 2024-09-17
2635 Epigenomic, transcriptomic and proteomic characterizations of reference samples
Nepal, C.; Chen, W.; Chen, Z.; Wroble, J. A.; Xie, L.; Liao, W.; Xiao, C.; Farmer, A.; Moos, M.; Jones, W.; Chen, X.; Wang, C.
10.1101/2024.09.09.612110 — genomics — Posted on 2024-09-17
2638 Asparagine availability controls B cell homeostasis
Yazicioglu, Y. F.; Marin, E.; Bentkowska, K.; Andrew, H.; Mitchell, R.; Wong, Z. Y.; Fergusson, J.; Borsa, M.; Johnstone, J. C.; Ali, M.; Kronsteiner, B.; Furlani, I. L.; MacRae, J. I.; Devine, M. J.; Coles, M.; Buckley, C.; Dunachie, S.; Clarke, A.
10.1101/2023.04.03.535433 — immunology — Posted on 2024-09-17
2639 The transcriptional response of cortical neurons to concussion reveals divergent fates after injury
Alkaslasi, M. R.; Lloyd, E. Y. H.; Gable, A. S.; Silberberg, H.; Yarur, H. E.; Tsai, V. S.; Sohn, M.; Margolin, G.; Tejeda, H. A.; Le Pichon, C. E.
10.1101/2024.02.26.581939 — neuroscience — Posted on 2024-09-17
2641 Brain-wide microstrokes affect the stability of memory circuits in the hippocampus
Heiser, H.; Kiessler, F.; Roggenbach, A.; Ibanez, V.; Wieckhorst, M.; Helmchen, F.; Gjorgjieva, J.; Wahl, A.-S.
10.1101/2024.09.17.612757 — neuroscience — Posted on 2024-09-17
2642 Feasibility of laminar functional quantitative susceptibility mapping
Straub, S.; Zhou, X.; Tao, S.; Westerhold, E. M.; Jin, J.; Middlebrooks, E. H.
10.1101/2024.09.16.613070 — neuroscience — Posted on 2024-09-17
2647 A Comparison of Tokenization Impact in AttentionBased and State Space Genomic Language Models
Lindsey, L. M.; Pershing, N. L.; Habib, A.; Stephens, W. Z.; Blaschke, A. J.; Sundar, H.
10.1101/2024.09.09.612081 — bioinformatics — Posted on 2024-09-17
2650 Staphylococcus aureus counters organic acid anion-mediated inhibition of peptidoglycan cross-linking through robust alanine racemase activity
Panda, S.; Jayasinghe, Y. P.; Shinde, D. D.; Bueno, E.; Stastny, A.; Bertrand, B. P.; Chaudhari, S. S.; Kielian, T.; Cava, F.; Ronning, D. R.; Thomas, V. C.
10.1101/2024.01.15.575639 — microbiology — Posted on 2024-09-17
2653 Targeting cancer-associated glycosylation for adoptive T cell therapy of gastro-intestinal and gynecological cancers
Zingg, A.; Ritschard, R.; Thut, H.; Buchi, M.; Holbro, A.; Oseledchyk, A.; Heinzelmann, V.; Buser, A.; Binder, M.; Zippelius, A.; Mantuano, N. R.; Laubli, H.
10.1101/2024.09.12.612750 — cancer biology — Posted on 2024-09-17
2654 p53 Regulates Nuclear Architecture to Reduce Carcinogen Sensitivity and Mutagenic Potential
King, D. A.; McCoy, D. E.; Perdyan, A.; Mieczkowski, J.; Douki, T.; Dionne, J. A.; Herrera, R. E.; Morrison, A. J.
10.1101/2024.09.14.613067 — cancer biology — Posted on 2024-09-17
2661 Engineering bacteriophages through deep mining of metagenomic motifs
Huss, P.; Kieft, K.; Meger, A.; Nishikawa, K.; Anantharaman, K.; Raman, S.
10.1101/2023.02.07.527309 — synthetic biology — Posted on 2024-09-17
2662 SVbyEye: A visual tool to characterize structural variation among whole-genome assemblies
Porubsky, D.; Guitart, X.; Yoo, D.; Dishuck, P. C.; Harvey, W. T.; Eichler, E. E.
10.1101/2024.09.11.612418 — bioinformatics — Posted on 2024-09-17
2666 Spinal V1 inhibitory interneuron clades differ in birthdate, projections to motoneurons and heterogeneity
Worthy, A. E.; Anderson, J. T.; Lane, A. R.; Gomez-Perez, L.; Wang, A. A.; Griffith, R. W.; Rivard, A. F.; Bikoff, J. B.; Alvarez, F. J.
10.1101/2023.11.29.569270 — neuroscience — Posted on 2024-09-17
2669 A Legionella pneumophila effector impedes host gene silencing to promote virulence
Toinon, J.; Rolando, M.; Charvin, M.; Filopon, D.; Schiavolin, L.; Sy, K. A.; Vu, H.-C.; Gallois-Montbrun, S.; Alam, A.; Barraud, P.; Rusniok, C.; Lombard, B.; Loew, D.; Buchrieser, C.; Navarro, L.
10.1101/2022.11.16.516792 — molecular biology — Posted on 2024-09-17
2670 Phenotypic diversity and shared genomic determinants among isolates causing a large incidence of disseminated gonococcal infections in Canada
Binepal, G.; Jurga, E.; Carruthers-Lay, D.; Krüger, S.; Zittermann, S.; Minion, J.; Diggle, M.; Alexander, D. C.; Martin, I.; Allen, V.; Parkinson, J.; Gray-Owen, S. D.
10.1101/2024.09.08.611882 — microbiology — Posted on 2024-09-17
2673 Interpretable high-resolution dimension reduction of spatial transcriptomics data by DeepFuseNMF
Tang, J.; Chen, Z.; Qian, Q.; Huang, S.; Yin, S.; He, Y.; He, X.; Ye, B.; Zhuang, Y.; Meng, H.; Xi, J.; Xi, R.
10.1101/2024.09.12.612666 — bioinformatics — Posted on 2024-09-17
2674 Accelerating Ligand Discovery for Insect Odorant Receptors
Comte, A.; Lalis, M.; Brajon, L.; Moracci, R.; Montagne, N.; Topin, J.; Jacquin Joly, E.; Fiorucci, S.
10.1101/2024.09.12.612620 — bioinformatics — Posted on 2024-09-17
2680 Screening the human druggable genome identifies ABHD17B as an anti-fibrotic target in hepatic stellate cells
Li, W.; Sparks, R. P.; Sun, C.; Yang, Y.; Pantano, L.; Kirchner, R.; Weilheimer, A.; Toles, B. J.; Chen, J. Y.; Moran, S. P.; Barrera, V.; Li, Z.; Zhou, P.; Brassil, M. L.; Wrobel, D.; Sui, S. J. H.; Aspnes, G.; Schuler, M.; Smith, J.; Medoff, B. D.; Zhou, C.; Boustany-Kari, C. M.; Rippmann, J. F.; Santos, D. M.; Doerner, J. F.; Mullen, A. C.
10.1101/2023.08.07.551744 — cell biology — Posted on 2024-09-17
2684 The H3K4me3 binding ALFIN-LIKE proteins recruit SWR1 for gene-body deposition of H2A.Z
Xu, L.; Wang, Y.; Li, X.; Hu, Q.; Adamkova, V.; Xu, J.; Harris, C. J.; Ausin, I.
10.1101/2024.09.12.612642 — plant biology — Posted on 2024-09-17
2687 Promising effects of duck vaccination against highly pathogenic avian influenza, France 2023-24
Guinat, C.; Fourtune, L.; Lambert, S.; Martin, E.; Gerbier, G.; Jimenez Pellicer, A.; Guerin, J.-L.; Vergne, T.
10.1101/2024.08.28.609837 — ecology — Posted on 2024-09-17
2692 Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling
Piletic, K.; Kayvanjoo, A. H.; Richter, F. C.; Borsa, M.; Lechuga-Vieco, A. V.; Popp, O.; Grenet, S.; Ko, J. K. L.; Zec, K.; Kyriazi, M.; Koneva, L.; Sansom, S.; Mertins, P.; Powrie, F.; Alsaleh, G.; Simon, A. K.
10.1101/2024.09.17.613382 — cell biology — Posted on 2024-09-17
2697 The Pattern and Staging of Brain Atrophy in Spinocerebellar Ataxia Type 2 (SCA2): MRI Volumetrics from ENIGMA-Ataxia
Robertson, J. W.; Adanyeguh, I. M.; Bender, B.; Boesch, S.; Brunetti, A.; Cocozza, S.; Coutinho, L.; Deistung, A.; Diciotti, S.; Dogan, I.; Durr, A.; Fernandez-Ruiz, J.; Göricke, S. L.; Grisoli, M.; Han, S.; Mariotti, C.; Marzi, C.; Mascalchi, M.; Mochel, F.; Nachbauer, W.; Nanetti, L.; Nigri, A.; Ono, S. E.; Onyike, C. U.; Prince, J. L.; Reetz, K.; Romanzetti, S.; Sacca, F.; Synofzik, M.; Teive, H. A. G.; Thomopoulos, S. I.; Thompson, P. M.; Timmann, D.; Ying, S. H.; Harding, I. H.; Hernandez-Castillo, C. R.
10.1101/2024.09.16.613281 — neuroscience — Posted on 2024-09-17
2700 Demographic responses to climatic changes during the Final Palaeolithic in Europe
Schmidt, I.; Gehlen, B.; Winkler, K.; Arrizabalaga, A.; Arts, N.; Bicho, N.; Crombe, P.; Eriksen, B. V.; Grimm, S. B.; Kapustka, K.; Langlais, M.; Mevel, L.; Naudinot, N.; Nerudova, Z.; Niekus, M.; Peresani, M.; Riede, F.; Sauer, F.; Schön, W.; Sobkowiak-Tabaka, I.; Vandendriessche, H.; Weber, M.-J.; Zander, A.; Zimmermann, A.; Maier, A.
10.1101/2024.09.11.612499 — ecology — Posted on 2024-09-17
2702 The global spectrum of tree crown architecture
Jucker, T.; Fischer, F.; Chave, J.; Coomes, D.; Caspersen, J.; Ali, A.; Panzou, G.; Feldpausch, T.; Falster, D.; Usoltsev, V.; Jackson, T.; Adu-Bredu, S.; Alves, L.; Aminpour, M.; Angoboy, I.; Anten, N.; Antin, C.; Askari, Y.; Munoz, R.; Ayyappan, N.; Banin, L.; Barbier, N.; Battles, J.; Beeckman, H.; Bocko, Y.; Bond-Lamberty, B.; Bongers, F.; Bowers, S.; Breugel, M.; Chantrain, A.; Chaudhary, R.; Dai, J.; Dalponte, M.; Dimobe, K.; Domec, J.-C.; Doucet, J.-L.; Dupuy-Rada, J.; Duursma, R.; Enriquez, M.; Ewijk, K.; Farfan-Rios, W.; Fayolle, A.; Ferretti, M.; Forni, E.; Forrester, D.; Gilani, H.;
10.1101/2024.09.14.613032 — ecology — Posted on 2024-09-17
2704 Evaluating Physiological Indicators in Detecting Deception using the Comparison Question Test (CQT)
Rashid, A. M. S.; Carmichael, B.; Su, C.; Shi, K.; Lim, K.; Kumar, P. S.; Wan, N. J.; Govil, E.; Yap, D.
10.1101/2024.09.01.609623 — bioengineering — Posted on 2024-09-17
2706 On the quest for novelty in ecology
Ottaviani, G.; Martinez, A.; Petit Bon, M.; Mammola, S.
10.1101/2023.02.27.530333 — ecology — Posted on 2024-09-17
2707 Utilization and degradation of laminarin-based substrates by marine yeasts suggests their niche-specific role in microbial loop dynamics.
Arslan-Gatz, B.; Schultz-Johansen, M.; Hollwedel, T.-N.; Niggemeier, S.; Nimzyk, R.; Wichels, A.; Gerdts, G.; Hehemann, J.-H.; Harder, T.; Reich, M.
10.1101/2024.09.13.612705 — microbiology — Posted on 2024-09-17
2708 Repressing ABCB7 Potentiates Cisplatin Response in Pediatric Group 3 Medulloblastoma by Triggering Ferroptosis
Kanchan, R. K.; Perumal, N.; Khan, P.; Doss, D.; Gopalakrishnan, P.; Chirravuri Venkata, R.; Thapa, I.; Vengoji, R.; Kaushal, J.; Siddiqui, J. A.; Nasser, M. W.; Batra, S. K.; Mahapatra, S.
10.1101/2022.01.24.477587 — cancer biology — Posted on 2024-09-17
2710 Linker histone regulates the myeloid versus lymphoid bifurcation of multipotent hematopoietic stem and progenitors
Karatepe, K.; Mafra de Faria, B.; zhang, j.; Chen, X.; Pinto, H.; Fyodorov, D.; Sefik, E.; Willcockson, M.; Flavell, R.; Skoultchi, A. I.; Guo, S.
10.1101/2024.09.16.613227 — developmental biology — Posted on 2024-09-17
2712 Neurophysiological evidence of sensory prediction errors driving speech sensorimotor adaptation
Kim, K. S.; Hinkley, L. B.; Brent, K.; Gaines, J. L.; Pongos, A. L.; Gupta, S.; Dale, C. L.; Nagarajan, S. S.; Houde, J. F.
10.1101/2023.10.22.563504 — neuroscience — Posted on 2024-09-17
2716 A simple framework for agent-based modeling with extracellular matrix
Metzcar, J.; Duggan, B. S.; Fischer, B.; Murphy, M.; Heiland, R.; Macklin, P.
10.1101/2022.11.21.514608 — systems biology — Posted on 2024-09-17
2717 Single-particle tracking reveals heterogeneous PIEZO1 diffusion
Ly, A. T.; Freites, J. A.; Bertaccini, G. A.; Evans, E. L.; Dickinson, G. D.; Tobias, D. J.; Pathak, M. M.
10.1101/2022.09.30.510193 — biophysics — Posted on 2024-09-16
2720 SMURF1/2 are novel regulators of WNK1 stability
Jaykumar, A. B.; Plumber, S.; Binns, D.; Wichaidit, C.; Luby-Phelps, K.; Cobb, M. H.
10.1101/2024.07.31.606092 — biochemistry — Posted on 2024-09-16
2723 RNA language models predict mutations that improve RNA function
Shulgina, Y.; Trinidad, M. I.; Langeberg, C. J.; Nisonoff, H.; Chithrananda, S.; Skopintsev, P.; Nissley, A. J.; Patel, J.; Boger, R. S.; Shi, H.; Yoon, P. H.; Doherty, E. E.; Pande, T.; Iyer, A. M.; Doudna, J. A.; Cate, J. H. D.
10.1101/2024.04.05.588317 — synthetic biology — Posted on 2024-09-16
2724 Impaired Myofibroblast Proliferation is a Central Feature of Pathologic Post-Natal Alveolar Simplification
Khan, I. S.; Molina, C.; Ren, X.; Auyeung, V. C.; Cohen, M.; Tsukui, T.; Atakilit, A.; Sheppard, D.
10.1101/2023.12.21.572766 — physiology — Posted on 2024-09-16
2725 3'UTR-directed, kinase proximal mRNA decay inhibits C/EBPβ phosphorylation/activation to suppress senescence in tumor cells
Salotti, J.; Asif, N.; Basu, S.; Das, A.; Yang, M.; Karim, B.; Saylor, K.; Martin, N.; Scheiblin, D. A.; Misra, S.; Luke, B.; Andresson, T.; Lockett, S.; Tessarollo, L.; Johnson, P. F.
10.1101/2022.03.29.486281 — cancer biology — Posted on 2024-09-16
2728 MAPK/ERK signaling in gliomas modulates interferon responses, T cell recruitment, enhances tumor-microglia crosstalk, and drives immune checkpoint blockade efficacy.
Kim, K.-S.; Zhang, J.; Arrieta, V. A.; Dmello, C.; Grabis, E.; Habashy, K.; Duffy, J.; Zhao, J.; Gould, A.; Chen, L.; Hu, J.; Balyasnikova, I.; Chand, D.; Levey, D.; Canoll, P.; Zhao, W.; Sims, P.; Rabadan, R.; Pandey, S.; Zhang, B.; Lee-Chang, C.; Heiland, D. H.; Sonabend, A. M.
10.1101/2024.09.11.612571 — cancer biology — Posted on 2024-09-16
2731 Pervasive Induction of Regulatory Mutation Microclones in Sun-exposed Skin
Menon, V.; Garcia-Ruiz, A.; Neveu, S.; Cartmel, B.; Ferrucci, L. M.; Palmatier, M.; Ko, C.; Tsai, K. Y.; Nakamura, M.; Kim, S. R.; Girardi, M.; Kornacker, K.; Brash, D.
10.1101/2024.09.12.612526 — genomics — Posted on 2024-09-16
2734 Commitment to cytokinetic furrowing requires the coordinate activity of microtubules and Plk1
Day, C. A.; Langfald, A.; Lukes, T.; Middlebrook, H.; Vaughan, K. T.; Daniels, D. J.; Hinchcliffe, E. H.
10.1101/2024.09.16.612913 — cell biology — Posted on 2024-09-16
2736 Functional analyses and integrated mechanisms of cellular destruction by L-amino acid oxidase
Prak, K.; Luft, C.; Tsefou, E.; Chavez-Olortegui, C.; Kriston-Vizi, J.; Ketteler, R.; Braga, V.
10.1101/2024.09.16.613219 — cell biology — Posted on 2024-09-16
2738 RalB uncoupled exocyst mediates endothelial Weibel-Palade body exocytosis
Yang, M.; Boye-Doe, A.; Abosabie, S. A. S.; Barr, A. M.; Mendez, L. M.; Sharda, A. V.
10.1101/2024.09.16.613344 — cell biology — Posted on 2024-09-16
2739 RNA secondary structure ensemble mapping in a living cell identifies conserved RNA regulatory switches and thermometers
Borovska, I.; Zhang, C.; Morandi, E.; van den Homberg, D.; Wolfinger, M. T.; Velema, W.; Incarnato, D.
10.1101/2024.09.16.613214 — molecular biology — Posted on 2024-09-16
2740 Novel naphthyridones targeting Pannexin 1 for colitis management
Hsueh, W.-Y.; Wu, Y.-L.; Weng, M.-T.; Liu, S.-Y.; Santavanond, J. P.; Liu, Y.-C.; Lin, C.-I.; Lai, C.-N.; Lu, Y.-R.; Hsu, J. Y.; Gao, H.-Y.; Lee, J.-C.; Wei, S.-C.; Lyu, P.-C.; Poon, I. K.; Hsieh, H.-P.; Chiu, Y.-H.
10.1101/2024.09.15.613164 — molecular biology — Posted on 2024-09-16
2741 Complete Genomic Characterization of Global Pathogens, Respiratory Syncytial Virus (RSV), and Human Norovirus (HuNoV) Using Probe-based Capture Enrichment.
Doddapaneni, H.; Bhamidipati, S. V.; Surathu, A.; Chao, H.; Paiva Agustinho, D.; Xiang, Q.; Kottapalli, K.; Santhanam, A.; Momin, Z.; Walker, K.; Menon, V. K.; Weissenberger, G. M.; Emerick, N.; Mahjabeen, F.; Meng, Q.; Hu, J.; Sucgang, R.; Henke, D. M.; Sedlazeck, F.; Khan, Z.; Metcalf, G. A.; Avadhanula, V.; Piedra, P. A.; Ramani, S.; Atmar, R. L.; Estes, M. K.; Petrosino, J. F.; Gibbs, R.; Muzny, D.; Javornik Cregeen, S. J.
10.1101/2024.09.16.613242 — molecular biology — Posted on 2024-09-16
2742 Exploring putative enteric methanogenesis inhibitors using molecular simulations and a graph neural network
Aryee, R.; Mohammed, N. S.; Dey, S.; B, A.; Nadendla, S.; Sajeevan, K. A.; Beck, M.; Frazier, A. N.; Koziel, J.; Mansell, T.; Chowdhury, R.
10.1101/2024.09.16.613350 — molecular biology — Posted on 2024-09-16
2745 Structure-guided assembly of an influenza spike nanobicelle vaccine provides pan H1 intranasal protection
Myers, M. L.; Gallagher, J. R.; Woolfork, D. D.; Khorrami, N. D.; Park, W. B.; Maldonado-Puga, S.; Bohrnsen, E.; Schwarz, B. H.; Alves, D. A.; Bock, K. W.; Dearborn, A. D.; Harris, A. K.
10.1101/2024.09.16.613335 — microbiology — Posted on 2024-09-16
2747 Making yogurt with the ant holobiont uncovers bacteria, acids, and enzymes for food fermentation
Sinotte, V. M.; Ramos Viana, V.; Vasquez, D. P.; Sirakova, S. M.; Valeron, N. R.; Cuesta Mate, A.; Taylor Parkins, S. K.; Velasco, E. M.; Zilber, D.; Munk, R.; Andersen, S. B.; Dunn, R. R.; Jahn, L. J.
10.1101/2024.09.16.613207 — microbiology — Posted on 2024-09-16
2750 Decoding Cytokine Networks in Ulcerative Colitis to Identify Pathogenic Mechanisms and Therapeutic Targets
Olbei, M. L.; Hautefort, I.; Thomas, J. P.; Csabai, L. L.; Bogar, B.; Ibraheim, H.; Saifuddin, A.; Modos, D.; Powell, N.; Korcsmaros, T.
10.1101/2024.09.12.612623 — systems biology — Posted on 2024-09-16
2752 De novo RNA base editing in plant organelles with engineered synthetic P-type PPR editing factors
Mathieu, S.; Lesch, E.; Garcia, S.; Graindorge, S.; Schallenberg-Rudinger, M.; Hammani, K.
10.1101/2024.09.13.612905 — synthetic biology — Posted on 2024-09-16
2754 Comparative Analysis of Stain-Free Fourier Ptychographic Microscopy and Traditional Histopathological Light Microscopy in Renal Membranous Nephropathy
Valentino, M.; Bianco, V.; D'Ambrosio, G.; Paulli, M.; Smaldone, G.; Brancato, V.; Miccio, L.; Salvatore, M.; Gambacorta, M.; Ferraro, P.
10.1101/2024.09.12.612640 — pathology — Posted on 2024-09-16
2756 Multifocal cutaneous neoplastic vascular proliferations in a rainbow boa (Epicrates cenchria) collection with boid inclusion body disease
Broering Ferreira, A.; Fonteque, J.; Withoeft, J.; Assis Casagrande, R.; da Costa, U.; Imkamp, F.; Goller, P.; Baggio, F.; Hepojoki, J.; Hetzel, U.; Kipar, A.
10.1101/2024.09.12.612643 — pathology — Posted on 2024-09-16
2757 Dynamics of microcompartment formation at the mitosis-to-G1 transition
Goel, V. Y.; Aboreden, N. G.; Jusuf, J. M.; Zhang, H.; Mori, L.; Mirny, L. A.; Blobel, G.; Banigan, E. J.; Hansen, A. S.
10.1101/2024.09.16.611917 — biophysics — Posted on 2024-09-16
2761 The L1CAM SAX-7 is an antagonistic modulator of Erk signaling
Moseley-Alldredge, M.; Aragon, C.; Vargus, M.; Alley, D.; Somia, N.; Chen, L.
10.1101/2024.09.14.613091 — genetics — Posted on 2024-09-16
2763 Expansion microscopy allows quantitative characterisation of structural organisation of platelet aggregates
Faulkner, E. L.; Pike, J. A.; Garlick, E.; Neely, R. K.; Styles, I. B.; Watson, S. P.; Poulter, N. S.; Thomas, S. G.
10.1101/2024.09.16.613233 — cell biology — Posted on 2024-09-16
2765 The endosymbiont Rickettsiella viridis increases the virulence of Diuraphis noxia but reduces alate frequency
Gu, X.; Gill, A.; Yang, Q.; Ross, P. A.; Yeatman, E.; Berran, M.; Stelmach, M.; Sharma, S.; Umina, P. A.; Hoffmann, A. A.
10.1101/2024.09.15.613162 — microbiology — Posted on 2024-09-16
2766 Evaluating Best Practices for Isolating Pyrophilous Bacteria and Fungi from Burned Soil
Enright, D. J.; Quaal, R. J.; Veerabahu, A.; Nguyen, A.; Maddox, J.; Glassman, S. I.
10.1101/2024.09.16.612975 — microbiology — Posted on 2024-09-16
2767 The Plastisphere: Marine fungi communities in the plastics age
Kirstein, I.; Reich, M.; Yang, Y.; Timmermann, M.; Wichels, A.; Gerdts, G.
10.1101/2024.09.16.613245 — microbiology — Posted on 2024-09-16
2768 Extensive intrachromosomal duplications in a virulence-associated fungal accessory chromosome
Dijkstra, J.; van Westerhoven, A. C.; Gomez-Gil, L.; Aguilera-Galvez, C.; Nakasato-Tagami, G.; Garnier, S. D.; Yamazaki, M.; Arie, T.; Kamakura, T.; Arazoe, T.; Di Pietro, A.; Seidl, M. F.; Kema, G. H. J.
10.1101/2024.09.16.611982 — microbiology — Posted on 2024-09-16
2769 Spatial microenvironments tune immune response dynamics in the Drosophila larval fat body
Schlomann, B. H.; Pai, T.-W.; Sandhu, J.; Ferrer Imbert, G.; Graham, T. G. W.; Garcia, H. G.
10.1101/2024.09.12.612587 — immunology — Posted on 2024-09-16
2770 Modeling suggests SARS-CoV-2 rebound after nirmatrelvir-ritonavir treatment is driven by target cell preservation coupled with incomplete viral clearance
Phan, T.; Ribeiro, R.; Edelstein, G. E.; Boucau, J.; Uddin, R.; Marino, C.; Liew, M. Y.; Barry, M.; Choudhary, M. C.; Tien, D.; Su, K.; Reynolds, Z.; Li, Y.; Sagar, S.; Vyas, T. D.; Kawano, Y.; Sparks, J. A.; Hammond, S. P.; Wallace, Z.; Vyas, J. M.; Li, J. Z.; Siedner, M. J.; Barczak, A. K.; Lemieux, J. E.; Perelson, A. S.
10.1101/2024.09.13.613000 — immunology — Posted on 2024-09-16
2773 Flexible and robust cell type annotation for highly multiplexed tissue images
Sun, H.; Yu, S.; Casals, A. M.; Bäckström, A.; Lu, Y.; Lindskog, C.; Lundberg, E.; Murphy, R. F.
10.1101/2024.09.12.612510 — bioinformatics — Posted on 2024-09-16
2775 PEARL: Protein Eluting Alginate with Recombinant Lactobacilli
Tadimarri, V. S.; Blanch-Asensio, M.; Deshpande, K.; Baumann, J.; Baumann, C.; Mueller, R.; Trujillo, S.; Sankaran, S.
10.1101/2024.09.12.612671 — bioengineering — Posted on 2024-09-16
2776 Interpenetrating networks of fibrillar and amorphous collagen promote cell spreading and hydrogel stability
Brunel, L. G.; Long, C. M.; Christakopoulos, F.; Cai, B.; Johansson, P. K.; Singhal, D.; Enejder, A.; Myung, D.; Heilshorn, S. C.
10.1101/2024.09.11.612534 — bioengineering — Posted on 2024-09-16
2777 High-speed 4D fluorescence light field tomography of whole freely moving organisms
Zhou, K. C.; Cook, C.; Chakraborty, A.; Bagwell, J.; Jönsson, J.; Lee, K. C.; Yang, X.; Xu, S.; Balla, R.; Harfouche, M.; Fox, D. T.; Bagnat, M.; Horstmeyer, R.
10.1101/2024.09.16.609432 — animal behavior and cognition — Posted on 2024-09-16
2782 Establishment of an optimized and automated workflow for whole brain probing of neuronal activity.
CABRERA, S.; VACHOUD, N.; BREUILLY, M.; DESMERCIERES, S.; MACIEL, R. M.; MEYER-DILHET, G.; ELLOUZE, S.; COURCHET, J.; LUPPI, P.-H.; MANDAIRON, N.; RAINETEAU, O.
10.1101/2024.09.16.611953 — neuroscience — Posted on 2024-09-16
2785 Scheduled feeding improves behavioral outcomes and reduces inflammation in a mouse model of Fragile X syndrome.
Wang, H.-B.; Smale, N. E.; Brown, S. H.; Zhou, D.; Mulji, A.; Villanueva, S. A.; Nguyen-Ngo, K.; Harvey, J. R.; Ghiani, C. A.; Colwell, C. S.
10.1101/2024.09.16.613343 — neuroscience — Posted on 2024-09-16
2786 A mosaic of whole-body representations in human motor cortex
Deo, D. R.; Okorokova, E. V.; Pritchard, A. L.; Hahn, N. V.; Card, N. S.; Nason-Tomaszewski, S. R.; Jude, J.; Hosman, T.; Choi, E. Y.; Qiu, D.; Meng, Y.; Wairagkar, M.; Nicolas, C.; Kamdar, F. B.; Iacobacci, C.; Acosta, A.; Hochberg, L. R.; Cash, S. S.; Williams, Z. M.; Rubin, D. B.; Brandman, D. M.; Stavisky, S. D.; AuYong, N.; Pandarinath, C.; Downey, J. E.; Bensmaia, S. J.; Henderson, J. M.; Willett, F. R.
10.1101/2024.09.14.613041 — neuroscience — Posted on 2024-09-16
2787 Positional information drives distinct traits in transcriptomically identified neuronal types
Shainer, I.; Kappel, J. M.; Laurell, E.; Donovan, J. C.; Schneider, M. W.; Kuehn, E.; Arnold-Ammer, I.; Stemmer, M.; Larsch, J.; Baier, H.
10.1101/2024.09.15.613138 — neuroscience — Posted on 2024-09-16
2788 Rebalance the inhibitory system in the elderly brain: Influence of balance learning on GABAergic inhibition and functional connectivity
Liu, X.; Scherrer, S.; Egger, S.; Lim, S.-I.; Lauber, B.; Jelescu, I. O.; Griffa, A.; Gambarota, G.; Taube, W.; Xin, L.
10.1101/2024.09.16.613232 — neuroscience — Posted on 2024-09-16
2789 Synaptic Specializations at Dopamine Release Sites Orchestrate Efficient and Precise Neuromodulatory Signaling
Bulumulla, C.; Walpita, D.; Iyer, N.; Eddison, M.; Patel, R.; Alcor, D.; Ackerman, D.; Beyene, A. G.
10.1101/2024.09.16.613338 — neuroscience — Posted on 2024-09-16
2790 Topical Ophthalmic Administration of VIAN-c4551 Antiangiogenic Peptide for Diabetic Macular Edema: Preclinical Efficacy and Ocular Pharmacokinetics
Adan-Castro, E.; Zamora, M.; Granados-Carrasco, D.; Siqueiros-Marquez, L.; Garcia-Rodrigo, J. F.; Bertsch, T.; Triebel, J.; Martinez de la Escalera, G.; Robles, J. P.; Clapp, C.
10.1101/2024.09.11.612517 — pharmacology and toxicology — Posted on 2024-09-16
2793 Particle algorithms for animal movement modelling in autonomous receiver networks
Lavender, E.; Scheidegger, A.; Albert, C.; Biber, S.; Illian, J.; Thorburn, J.; Smout, S.; Moor, H.
10.1101/2024.09.16.613223 — animal behavior and cognition — Posted on 2024-09-16
2794 Opportunistic partner choice among arctic plants and root-associated fungi is driven by environmental conditions.
Parisy, B.; Schmidt, N. M.; Cirtwill, A. R.; Villa-Galaviz, E.; Tiusanen, M.; Siren, J.; Klutsch, C. F. C.; Aspholm, P. E.; Raundrup, K.; Vesterinen, E. J.; Wirta, H.; Roslin, T.
10.1101/2024.09.14.613029 — ecology — Posted on 2024-09-16
2795 Thorax temperature and niche characteristics as predictors of abundance of Amazonian Odonata
Calvao, L. B.; Faria, A. P. J.; de Paiva, C. K. S.; Oliveira-Junior, J. M. B.; Muzon, J.; Cordoba-Aguilar, A.; Juen, L.
10.1101/2024.09.14.613059 — ecology — Posted on 2024-09-16
2796 NR2F2 regulation of interstitial to fetal Leydig cell differentiation in the testis: insights into differences of sex development
Estermann, M. A.; Grimm, S.; Kitakule, A.; Rodriguez, K. F.; Brown, P.; McClelland, K.; Amato, C. M.; Yao, H. H.-C.
10.1101/2024.09.16.613312 — developmental biology — Posted on 2024-09-16
2799 Linker histone regulates the myeloid versus lymphoid bifurcation of multipotent hematopoietic stem and progenitors
Guo, S.; Karatepe, K.; Mafra de Faria, B.; zhang, j.; Chen, X.; Pinto, H.; Fyodorov, D.; Sefik, E.; Willcockson, M.; Flavell, R.; Skoultchi, A. I.
10.1101/2024.09.16.613227 — developmental biology — Posted on 2024-09-16
2803 Global and compartmentalized serotonergic control of sensorimotor integration underlying motor adaptation
Haruvi, R.; Barbara, R.; Shainer, I.; Rosenberg, A. M.; Moshe, L.; Malamud, D.; Toledano, J.; Braun, D.; Baier, H.; Kawashima, T.
10.1101/2024.09.15.613094 — neuroscience — Posted on 2024-09-16
2804 Probing the role of Nogo receptor homolog NgR2 in setting up cochlear connectivity
Karagulyan, N.; Überegger, M.; Qi, Y.; Babai, N.; Hofer, F.; Johnson Chacko, L.; Wang, F.; Luque, M.; Glueckert, R.; Schrott-Fischer, A.; Hua, Y.; Moser, T.; Bandtlow, C.
10.1101/2024.09.16.613011 — neuroscience — Posted on 2024-09-16
2805 Optic nerve crush does not induce retinal ganglion cell loss in the contralateral eye.
Schoot Uiterkamp, F. E.; Maes, M. E.; Alamalhoda, M.; Firoozi, A.; Colombo, G.; Siegert, S.
10.1101/2024.09.16.613181 — neuroscience — Posted on 2024-09-16
2809 Glutamatergic regulation of miRNA-containing exosome precursor trafficking and secretion from cortical neurons
Bertolio, M.; Li, Q.; Mowry, F. E.; Reynolds, K.; Wei, H.; Keum, K.; Jarvis, R.; Wu, J.; Yang, Y.
10.1101/2024.09.15.613153 — neuroscience — Posted on 2024-09-16
2810 Exploring Differences in Functional Connectivity in Australian Rules Football Players : A Resting-State fMRI Study on the Default Mode Network
Tran, M.; Shrikumar, A.; Hellewell, S. C.; Welton, T.; Kirkby, M.; Maller, J. J.; Smith, P.; Pearce, A.; Grieve, S. M.
10.1101/2024.09.15.613156 — neuroscience — Posted on 2024-09-16
2811 Genetic-Dependent Brain Signatures of Resilience: Interactions among Childhood Abuse, Genetic Risks and Brain Function
Lu, H.; Rolls, E. T.; Liu, H.; Stein, D. J.; Sahakian, B. J.; Elliott, R.; Jia, T.; Xie, C.; Xiang, S.; Wang, N.; Banaschewski, T.; Bokde, A. L. W.; Desrivieres, S.; Flor, H.; Grigis, A.; Garavan, H.; Heinz, A.; Bruhl, R.; Martinot, J.-L.; Martinot, M.-L. P.; Artiges, E.; Nees, F.; Orfanos, D. P.; Lemaitre, H.; Poustka, L.; Hohmann, S.; Holz, N.; Frohner, J. H.; Smolka, M. N.; Vaidya, N.; Walter, H.; Whelan, R.; Schumann, G.; Feng, J.; Luo, Q.
10.1101/2024.09.16.612982 — neuroscience — Posted on 2024-09-16
2814 FEATURE-SPECIFIC ANTICIPATORY PROCESSING FADES DURING HUMAN SLEEP
Topalidis, P. I.; Reisinger, L.; Shubert, J.; Ameen, M. S.; Weisz, N.; Schabus, M.
10.1101/2024.09.16.613294 — neuroscience — Posted on 2024-09-16
2816 Heterogeneous responses to embryonic critical period perturbations among different components of the Drosophila larval locomotor circuit
Krick, N.; Davies, J.; Coulson, B.; Sobrido-Camean, D.; Miller, M.; Oswald, M. C. W.; Zarin, A. A.; Baines, R.; Landgraf, M.
10.1101/2024.09.14.613036 — neuroscience — Posted on 2024-09-16
2822 Few-shot Algorithms for Consistent Neural Decoding (FALCON) Benchmark
Karpowicz, B. M.; Ye, J.; Fan, C.; Tostado-Marcos, P.; Rizzoglio, F.; Washington, C.; Scodeler, T.; de Lucena, D.; Nason-Tomaszewski, S. R.; Mender, M. J.; Ma, X.; Arneodo, E. M.; Hochberg, L. R.; Chestek, C. A.; Henderson, J. M.; Gentner, T. Q.; Gilja, V.; Miller, L. E.; Rouse, A. G.; Gaunt, R. A.; Collinger, J. L.; Pandarinath, C.
10.1101/2024.09.15.613126 — neuroscience — Posted on 2024-09-16
2823 Carboxy-terminal blockade of sortilin binding enhances progranulin gene therapy, a potential treatment for frontotemporal dementia
Kashyap, S. N.; Fox, S. N.; Wilson, K. I.; Murchison, C. F.; Ambaw, Y. A.; Walther, T. C.; Farese, R. V.; Arrant, A. E.; Roberson, E. D.
10.1101/2024.09.15.613118 — neuroscience — Posted on 2024-09-16
2826 TRPC3 suppression ameliorates synaptic dysfunctions and memory deficits in Alzheimer's disease
Liao, F.-F.; Wang, J.; Chen, L.; Wang, Z.; Zhang, S.; Ding, D.; Lin, G.; Zhang, H.; Boda, V. K.; Kong, D.; Ortyl, T. C.; Wang, X.; Lu, L.; Bezprozvanny, I.; Du, J.; Wu, Z.; Li, W.
10.1101/2024.09.16.611061 — neuroscience — Posted on 2024-09-16
2827 The transcription factor ZmbZIP75 promotes both grain filling and kernel dehydration in maize
Long, T.; Wang, Y.; Yang, J.; Liu, Z.; Mao, C.; Hu, Y.; Zhang, J.; Liu, H.; Liu, Y.; Fan, X.; Gao, L.; Huang, H.; Xie, Y.; Zhao, D.; Huang, Y.; Li, Y.
10.1101/2024.09.11.612493 — plant biology — Posted on 2024-09-16
2832 Mitochondrial iron transport via MFRN1 is required for erythroid cell cycle progression
Perfetto, M.; Danoff, A.; Ishfaq, M.; Monroe, H.; Mohideen, A.; Chen, M.; Stratman, A. N.; Okawa, S.; Yien, Y. Y.
10.1101/2022.08.22.504833 — developmental biology — Posted on 2024-09-16
2835 GLARE: Discovering Hidden Patterns in Spaceflight Transcriptome Using Representation Learning
Seo, D.; Strickland, H. F.; Zhou, M.; Barker, R.; Ferl, R. J.; Paul, A.-L.; Gilroy, S.
10.1101/2024.06.04.597470 — plant biology — Posted on 2024-09-16
2838 Mechanistic basis of lineage restriction
Wu, B.; Lee, J. H.; Foshay, K. M.; Zhang, L.; Fernandes, C. J.; Gao, B.; Dou, X.; Zhang, C. Z.; Fan, G.; Xiao, B. X.; Lahn, B. T.
10.1101/2024.08.07.606262 — developmental biology — Posted on 2024-09-16
2839 Single molecule Lipid Biosensors Mitigate Inhibition of Endogenous Effector Proteins
Holmes, V.; Ricci, M. M. C.; Weckerly, C. C.; Worcester, M.; Hammond, G. R.
10.1101/2024.09.11.612480 — cell biology — Posted on 2024-09-16
2840 Spatial transcriptomics unveils immune cellular ecosystems associated with patient survival in diffuse large B-cell lymphoma
Herrero, A. D.; Pelaez-Prestel, H. F.; Massenet-Regad, L.; Veyssiere, M.; Calvani, J.; Cristinelli, C.; Lehmann-Che, J.; Meignin, V.; Thieblemont, C.; Blanc, V.; Soumelis, V.; Tonnerre, P.
10.1101/2024.09.16.613252 — immunology — Posted on 2024-09-16
2841 Immune perturbations in human pancreas lymphatic tissues prior to and after type 1 diabetes onset
Golden, G. J.; Wu, V. H.; Hamilton, J. T.; Amses, K. R.; Shapiro, M. R.; Japp, A. S.; Liu, C.; Pampena, M. B.; Kuri-Cervantes, L.; Knox, J. J.; Gardner, J. S.; HPAP Consortium, ; Atkinson, M. A.; Brusko, T. M.; Prak, E. T. L.; Kaestner, K. H.; Naji, A.; Michael, B. R.
10.1101/2024.04.23.590798 — immunology — Posted on 2024-09-16
2842 Dual effects of ARX poly-alanine mutations in human cortical and interneuron development
Nieto-Estevez, V.; Varma, P.; Mirsadeghi, S.; Caballero, J.; Gamero-Alameda, S.; Hosseini, A.; Silvosa, M. J.; Thodeson, D. M.; Lybrand, Z. R.; Giugliano, M.; Navara, C.; Hsieh, J.
10.1101/2024.01.25.577271 — neuroscience — Posted on 2024-09-16
2846 Intestinal serotonergic vagal signaling as a mediator of microbiota-induced hypertension
de Araujo, A.; Sree Kumar, H.; Yang, T.; Alviter Plata, A.; Dirr, E. W.; Bearss, N.; Baekey, D. M.; Miller, D. S.; Donertas-Ayaz, B.; Ahmari, N.; Singh, A.; Kalinoski, A. L.; Garrett, T.; Martyniuk, C. J.; de Lartigue, G.; Zubcevic, J.
10.1101/2024.07.17.603451 — physiology — Posted on 2024-09-16
2848 Dads on duty: First account of nest sitting in barnacle ganders
Scheiber, I. B. R.; Slettenhaar, A. J.; Loonen, M. J. J. E.; de Jong, M. E.
10.1101/2024.07.19.604238 — animal behavior and cognition — Posted on 2024-09-16
2852 SACNet: A Multiscale Diffeomorphic Convolutional Registration Network with Prior Neuroanatomical Constraints for Flexible Susceptibility Artifact Correction in Echo Planar Imaging
Zeng, Z.; Zhang, J.; Liang, X.; Sun, L.; Zhang, Y.; Men, W.; Wang, Y.; Chen, R.; Zhang, H.; Tan, S.; Gao, J.-H.; Qin, S.; Tong, Q.; He, H.; Tao, S.; Dong, Q.; He, Y.; Zhao, T.
10.1101/2023.09.15.557874 — neuroscience — Posted on 2024-09-16
2853 The gut microbiome-linked long chain fatty acid stearate suppresses colorectal cancer
Tsenkova, M.; Brauer, M.; Pozdeev, V.; Kasakin, M.; Busi, S. B.; Schmoetten, M.; Cheung, D.; Meyers, M.; Rodriguez, F.; Gaigneaux, A.; Koncina, E.; Gilson, C.; Schlicker, L.; Herebian, D.; Schmitz, M.; de Nies, L.; Mayatepek, E.; Haan, S.; de Beaufort, C.; Cramer, T.; Meiser, J.; Linster, C.; Wilmes, P.; Letellier, E.
10.1101/2023.12.07.570549 — cancer biology — Posted on 2024-09-16
2857 Single molecule Lipid Biosensors Mitigate Inhibition of Endogenous Effector Proteins
Holmes, V.; Ricci, M. M. C.; Weckerly, C. C.; Worcester, M.; Hammond, G. R.
10.1101/2024.09.11.612480 — cell biology — Posted on 2024-09-16
2858 Bacterial genome encoded ParMs
Ali, S.; Koh, A.; Popp, D.; Tanaka, K.; Kitaoku, Y.; Miyazaki, N.; Iwasaki, K.; Mitsuoka, K.; Robinson, R. C.; Narita, A.
10.1101/2024.09.12.612785 — microbiology — Posted on 2024-09-16
2859 Hypoxic stress dysregulates functions of glioma-associated myeloid cells through epigenomic and transcriptional programs
Dzwigonska, M.; Rosa, P.; Kaza, B.; Cyranowski, S.; Ellert-Miklaszewska, A.; Kominek, A.; Obrebski, T.; Malik, A. R.; Piwocka, K.; Mieczkowski, J.; Kaminska, B.; Leszczynska, K. B.
10.1101/2024.09.12.612769 — cancer biology — Posted on 2024-09-16
2860 SOX2 drives fetal reprogramming and reversible dormancy in colorectal cancer
Baulies, A.; Moncho-Amor, V.; Drago-Garcia, D.; Kucharska, A.; Chakravarty, P.; Moreno-Valladares, M.; Cruces-Salguero, S.; Hubl, F.; Hutton, C.; Kim, H.; Matheu, A.; Lovell-Badge, R.; Li, V. S. W.
10.1101/2024.09.11.612412 — cancer biology — Posted on 2024-09-16
2862 YAP/TAZ signaling in allantois-derived cells is required for placental vascularization
Gao, S.; Thillaikumaran, T.; Dominguez, M. H.; Giang, W.; Hayes, K.; Chen, X.; Pace, J.; Bockman, J.; Jathan, D.; Sung, D. C.; Narayan, S.; Frankfurter, M.; Chen, M.; Mericko, P.; Yang, J.; Castro, M.; Potente, M.; Kahn, M.
10.1101/2024.09.15.613151 — developmental biology — Posted on 2024-09-16
2863 Ca2+-evoked sperm cessation determines embryo number in mammals.
Watanabe, H.; Ohara, D.; Chuma, S.; Takeuchi, Y.; Takano, T.; Katanaya, A.; Nakao, S.; Kaneko, A.; Oida, T.; Katsuno, T.; Uehata, T.; Takeo, T.; Okamoto, M.; Hirota, K.; Kondoh, G.
10.1101/2024.09.16.613169 — developmental biology — Posted on 2024-09-16
2865 Cell cycle-dependent S-sulfenyl proteomics uncover a redox switch in p21-CDK feedback governing the proliferation-senescence decision
Vorhauser, J.; Roumeliotis, T. I.; Leung, J. K.; Coupe, D.; Yu, L.; Bohlig, K.; Nadler, A.; Choudhary, J. S.; Mansfeld, J.
10.1101/2024.09.14.613007 — cell biology — Posted on 2024-09-16
2866 Inositol Hexaphosphate (InsP6) Activates the HDAC1/3 Epigenetic Axis toMaintain Intestinal Barrier Function
Chatterjee, S.; Preval, L. V.; Sin, Z.; Tran, N.; Ritter, K.; Su, X. B.; Centlivre, J. P.; Ragsac, S. J.; Van, R.; Park, S.; Han, M.; Liu, Q.; Hedlund, B. P.; Saiardi, A.; Jessen, H.; Guha, D. P.
10.1101/2024.09.15.613154 — cell biology — Posted on 2024-09-16
2871 Diversification and conservation of DNA binding specificities of SPL family of transcription factors
Li, M.; Yao, T.; Galli, M.; Lin, W.; Zhou, Y.; Chen, J.-G.; Gallavotti, A.; Huang, S.-s. C.
10.1101/2024.09.13.612952 — plant biology — Posted on 2024-09-16
2877 Bird Name-a-thon: Categorizing English bird names using crowdsourcing
Morrison, E. S.; Pandolfi, G. P.; Aguillon, S. M.; Ali, J. R.; Archard, O.; Baldassarre, D. T.; Baquero, I.; Bennett, K. F. P.; Bonney, K. M.; Bryant, R.; Catanach, R. M.; Catanach, T. A.; Chavoshan, I.; Davis, S. N.; Goodman, B. D.; Gulson-Castillo, E. R.; Hack, M.; Hudon, J.; Leighton, G. M.; Long, K. M.; Ma, Z.; McCoy, D. E.; McLaughlin, J. F.; Rueda Moreno, G.; Mota, T. M.; Noguchi, L.; Nwigwe, U.; Pegan, T.; Provost, K.; Rasband, S. A.; Salter, J. F.; Silvernail, L. C.; Simard, J. A.; Skeen, H. R.; Soto-Patino, J.; Suh, Y. H.; Wang, Q.; Warshauer, M. E.; Yan, S.; Zalinski, B.; Zhao, Z.; S
10.1101/2024.09.13.612884 — zoology — Posted on 2024-09-16
2878 Benchmarking open access publication rates for the pharmaceutical industry and research-intensive academic institutions
Rees, T. J.; Philippon, V.; Liew, A.; Baronikova, S.; Gattrell, W. T.; Gordon, J.; Koskenkorva, T. S.; Mysore, S.; Osorio, J.; Koder, T. J.
10.1101/2024.09.14.613042 — scientific communication and education — Posted on 2024-09-16
2881 The late onset Alzheimer's disease risk factor iRhom2/RHBDF2 is a modifier of microglial TREM2 proteolysis
Jocher, G.; Lichtenthaler, S. F.; Müller, S. A.; Hsia, H.-E.; Lastra-Osua, M.; Özcelik, G.; Hofmann, L. I.; Assfalg, M.; Dinkel, L.; Schlepckow, K.; Willem, M.; Haass, C.; Tahirovic, S.; Blobel, C. P.; Feng, X.
10.1101/2024.09.13.612888 — biochemistry — Posted on 2024-09-16
2882 Discovery of three novel neutralizing antibody epitopes on the human astrovirus capsid spike and mechanistic insights into virus neutralization
Lanning, S.; Aguilar-Hernandez, N.; Serrao, V. H. B.; Lopez, T.; O'Rourke, S. M.; Lentz, A.; Ricemeyer, L.; Espinosa, R.; Lopez, S.; Arias, C. F.; DuBois, R. M.
10.1101/2024.09.14.613010 — microbiology — Posted on 2024-09-16
2883 Treatment of anti-myeloperoxidase glomerulonephritis using recombinant deoxyribonuclease I is enhanced by adeno-associated virus gene therapy
Cao Le, A.; Gan, P.-Y.; Cheong, D. K. Y.; Oudin, V.; Dick, J.; Alikhan, M.; Mandwie, M.; Alexander, I.; Kitching, A. R.; Logan, G. J.; O'Sullivan, K. M.
10.1101/2024.09.09.612148 — immunology — Posted on 2024-09-16
2884 Transdiagnostic Symptom Domains are Associated with Head Motion During Multimodal Imaging in Children
Hercules, K.; Liu, Z.; Wei, J.; Venegas, G.; Ciocca, O.; Dyer, A.; Lee, G.; Santini-Bishop, S.; Shappell, H.; Gee, D. G.; Sukhodolsky, D. G.; Ibrahim, K.
10.1101/2024.09.13.612668 — neuroscience — Posted on 2024-09-16
2887 Scalable imaging-free spatial genomics through computational reconstruction
Hu, C.; Borji, M.; Marrero, G. J.; Kumar, V.; Weir, J. A.; Kammula, S. V.; Macosko, E. Z.; Chen, F.
10.1101/2024.08.05.606465 — genomics — Posted on 2024-09-16
2889 Cardiac differentiation roadmap for analysis of plasticity and balanced lineage commitment
Snabel, R. R.; Cofino-Fabres, C.; Baltissen, M.; Swach, V.; Passier, R.; Veenstra, G. J. C.
10.1101/2024.04.09.588683 — developmental biology — Posted on 2024-09-16
2891 Identification of a fungal antibacterial endopeptidase that modulates immune responses
Machata, S.; Bertsche, U.; Hoffmann, F.; Fattal, Z. M.; Kage, F.; Flak, M.; Iliou, A. N. J.; Hillmann, F.; von Eggeling, F.; Slevogt, H.; Brakhage, A. A.; Jacobsen, I. D.
10.1101/2024.09.13.612890 — microbiology — Posted on 2024-09-16
2892 Novel Genetically Encoded Probes for Functional Imaging of Cell Signaling by Polarization Microscopy
Miclea, P. S.; Nagy Markova, V.; Van den Eynde, R.; Vandenberg, W.; Sakhi, A.; Bondar, A.; Dedecker, P.; Lazar, J.
10.1101/2024.02.23.581811 — physiology — Posted on 2024-09-16
2894 Epigenetic control and inheritance of rDNA arrays
Potapova, T. A.; Kostos, P.; McKinney, S. A.; Borchers, M.; Haug, J. S.; Guarracino, A.; Solar, S.; Gogol, M. M.; Monfort Anez, G.; Gomes de Lima, L.; Wang, Y.; Hall, K. E.; Hoffman, S.; Garrison, E.; Phillippy, A. M.; Gerton, J. L.
10.1101/2024.09.13.612795 — genomics — Posted on 2024-09-16
2896 Cell differentiation controls iron assimilation in a choanoflagellate
Leon, F.; Espinoza-Esparza, J. M.; Deng, V.; Coyle, M. C.; Espinoza, S.; Booth, D. S.
10.1101/2024.05.25.595918 — evolutionary biology — Posted on 2024-09-16
2899 Tumorigencity decrease in Bcl-xL deficient MDCK cells ensuring the safety for influenza vaccine production
Zheng, J.; Li, B.; Jia, L.; Zhang, J.; Gong, Z.; Le, Y.; Nian, X.; Li, X.; Liu, B.; Yu, D.; Li, C.; Zhang, Z.
10.1101/2024.09.14.613056 — cell biology — Posted on 2024-09-16
2901 The XbnAb Cohort: 304 people with broadly neutralizing antibody activity to HIV-1
Pasin, C.; Rusert, P.; Schmidt, D.; Schanz, M.; Friedrich, N.; Abela, I. A.; Kusejko, K.; Niklaus, C.; Sickmann, M.; Weber, J.; Huber, M.; Manrique, A.; Rauch, A.; Calmy, A.; Cavassini, M.; Stöckle, M.; Notter, J.; Bernasconi, E.; Braun, D. L.; Günthard, H. F.; Kouyos, R. D.; Trkola, A.; the Swiss HIV Cohort Study,
10.1101/2024.09.13.612733 — immunology — Posted on 2024-09-16
2902 A structural MRI marker predicts individual differences in impulsivity and classifies patients with behavioral-variant frontotemporal dementia from matched controls
Godefroy, V.; Durand, A.; Simon, M.-C.; Weber, B.; Kable, J.; Lerman, C.; Bergström, F.; Levy, R.; Batrancourt, B.; Schmidt, L.; Plassmann, H.; Koban, L.
10.1101/2024.09.12.612706 — neuroscience — Posted on 2024-09-16
2909 SMARCAD1 Regulates R-Loops at Active Replication Forks Linked to Cancer Mutation Hotspots
Uruci, S.; Hoitsma, N. M.; Soler-Oliva, M. E.; Bayona-Feliu, A.; Gaggioli, V.; Rubio, M. L. G.; Lo, C. S. Y.; Bakker, C.; Marinello, J.; Manolika, E. M.; Capranico, G.; Luijsterburg, M. S.; Luger, K.; Aguilera, A.; Taneja, N.
10.1101/2024.09.13.612941 — genetics — Posted on 2024-09-15
2910 Environmental surveillance of soil-transmitted helminths and other enteric pathogens in settings without networked wastewater infrastructure
Siko, J. E. E.; Dahmer, K. J.; Manoharan, Z. Z.; Muthukumar, A.; Amato, H. K.; LeBoa, C.; Harris, M.; Janagaraj, V.; Manuel, M.; Varghese, T.; Houngbegnon, P.; Pilotte, N.; Bouko, B.; Saidou, S.; Luty, A. J. F.; Ramesh, R. M.; Ibikounle, M.; Ajjampur, S. S. R.; Pickering, A. J.
10.1101/2024.09.15.613066 — microbiology — Posted on 2024-09-15
2911 Tomato cystatin SlCYS8 as a trigger of drought tolerance and tuber yield in potato
Dorval, M.; Tremblay, J.; Veillet, G.; Chiasson, M.-A.; Goulet, M.-C.; Gumiere, T.; Pepin, S.; Goulet, C.; Michaud, D.
10.1101/2024.09.11.612519 — plant biology — Posted on 2024-09-15
2912 Unveiling the hidden interactome of CRBN molecular glues with chemoproteomics
Baek, K.; Metivier, R. J.; Roy Burman, S. S.; Bushman, J. W.; Lumpkin, R. J.; Abeja, D. M.; Lakshminarayan, M.; Yue, H.; Ojeda, S.; Verano, A. L.; Gray, N.; Donovan, K. A.; Fischer, E. S.
10.1101/2024.09.11.612438 — cancer biology — Posted on 2024-09-15
2913 U2AF1 S34F enhances tumorigenic potential of lung cells by exhibiting synergy with KRAS mutation and altering response to environmental stress
Liang, C. E.; Hrabeta-Robinson, E.; Behera, A.; Arevalo, C.; Fetter, I. J.; Soulette, C. M.; Thornton, A. M.; Sikandar, S.; Brooks, A. N.
10.1101/2024.09.11.612492 — cancer biology — Posted on 2024-09-15
2914 An updated AL-Base reveals ranked enrichment of immunoglobulin light chain variable genes in AL amyloidosis
Morgan, G. J.; Nau, A. N.; Wong, S.; Spencer, B. H.; Shen, Y.; Hua, A.; Bullard, M. J.; Sanchorawala, V.; Prokaeva, T.
10.1101/2024.09.11.612490 — bioinformatics — Posted on 2024-09-15
2915 Biofabrication of Small Vascular Graft with Acellular Human Amniotic Membrane: A Proof-of-Concept Study in Pig
Aung, O.; Rossi, P.; Dyer, M.; Stellpflug, A.; Zhai, Y.; Kenneth, A.; Wang, X.; Chang, J.; Chen, Y.; Tefft, B. J.; Wu, R.; Gu, L.; Wang, B.
10.1101/2024.09.11.612466 — bioengineering — Posted on 2024-09-15
2917 Engineering a Cell-Based Orthogonal Ubiquitin Transfer Cascade for Profiling the Substrates of RBR E3 Parkin
Fang, S.; Zhou, L.; Chen, G.; Wang, X.; Jeong, I. H.; Jacobs, S. E.; Kossmann, B. R.; Wei, W.; Zhang, J.; Jeong, G.; Ivanov, I.; Mabb, A. M.; Kiyokawa, H.; Zhao, B.; Yin, J.
10.1101/2024.09.14.613079 — biochemistry — Posted on 2024-09-15
2918 Inheritance bias of deletion-harbouring mtDNA in yeast: the role of copy number and intracellular selection
Kashko, N. D.; Karavaeva, I.; Glagoleva, E. S.; Logacheva, M. D.; Garushyants, S. K.; Knorre, D. A.
10.1101/2024.09.11.612442 — genetics — Posted on 2024-09-15
2919 NuRD chromatin remodeling is required to repair exogenous DSBs in the Caenorhabditis elegans germline
Ananthaswamy, D.; Funes, K.; Borges, T.; Roques, S. P.; Fassnacht, N.; El Jamal, S.; Checchi, P. M.; Lee, T. W.
10.1101/2024.09.14.613027 — genetics — Posted on 2024-09-15
2920 Discovery and functional analysis of a novel ALPK1 variant causing ROSAH syndrome
Snelling, T.; Olory-Garnotel, L.; Jeru, I.; Tusseau, M.; Cuisset, L.; Perlat, A.; Minard, G.; Benquey, T.; Maucourant, Y.; Wood, N. T.; Cohen, P.; Ziegler, A.
10.1101/2024.09.13.612837 — genetics — Posted on 2024-09-15
2921 Homoploid Hybridization Resolves the Origin of Octoploid Strawberries
Fan, Z.; Liston, A.; Soltis, D.; Soltis, P. S.; Ashman, T.-L.; Whitaker, V. M.
10.1101/2024.09.12.612680 — genetics — Posted on 2024-09-15
2924 A Comprehensive Proteogenomic and Spatial Analysis of Innate and Acquired Resistance of Metastatic Melanoma to Immune Checkpoint Blockade Therapies
wei, s.; Du, K.; Lan, H.; Yang, Z.; Deng, Y.; Wei, Z.; Frederick, D. T.; Lee, J.; Labrie, M.; Tian, T.; Moll, T.; Chen, Y.; Sullivan, R. J.; Mills, G. B.; Boland, G. M.; Flaherty, K.; liu, l.; Herlyn, M.; Zhang, G.
10.1101/2024.09.12.612675 — genetics — Posted on 2024-09-15
2925 Tenascin C Deletion Impairs Tendon Healing and Functional Recovery After Rotator Cuff Repair
TASHJIAN, R.; Zitnay, J.; Kazmers, N.; Veerabhadraiah, S.; Zelada, A.; Honeggar, M.; Smith, M.; Chalmers, P.; Henninger, H.; Jurynec, M.
10.1101/2024.09.11.612543 — genetics — Posted on 2024-09-15
2927 Genetic code expansion reveals site-specific lactylation in living cells reshapes protein function
Shao, C.; Tang, S.; Yu, S.; Liu, C.; Wan, T.; He, Z.; Yuan, Q.; Zhang, Y.; Zhan, M.; Zhang, H.; Wan, N.; Wu, S.; Tan, R. X.; Hao, H.; Ye, H.; Wang, N.
10.1101/2024.09.14.613019 — molecular biology — Posted on 2024-09-15
2928 Ex vivo and in vivo HIV-1 latency reversal by Mukungulu, a protein kinase C-activating African medicinal plant extract
Richard, K.; Yuan, Z.; Tang, H.-Y.; Goldman, A. R.; Kuthu, R.; Raphane, B.; Register, E. T.; Sharma, P.; Ross, B. N.; Morris, J.; Williams, D. E.; Cheney, C.; Wu, G.; Mounzer, K. C.; Laird, G. M.; Zuck, P.; Andersen, R. J.; Simonambango, S.; Andrae-Marobela, K.; Tietjen, I.; Montaner, L. J.
10.1101/2024.09.15.613141 — microbiology — Posted on 2024-09-15
2931 Conformational trajectory of the HIV-1 fusion peptide during CD4-induced envelope opening
Thakur, B.; Katte, R. H.; Xu, W.; Janowska, K.; Sammour, S.; Henderson, R.; Lu, M.; Kwong, P. D.; Acharya, P.
10.1101/2024.09.14.613076 — microbiology — Posted on 2024-09-15
2932 Positive feedback regulation between RpoS and BosR in the Lyme disease pathogen
Raghunandanan, S.; Priya, R.; Lin, G.; Alanazi, F. F.; Zoss, A.; Warren, E.; Yang, X. F.
10.1101/2024.09.14.613071 — microbiology — Posted on 2024-09-15
2933 CD4+ T cells drive corneal nerve damage but not epitheliopathy in an acute aqueous-deficient dry eye model
Vereertbrugghen, A.; Pizzano, M.; Cernutto, A.; Sabbione, F.; Keitelman, I. A.; Vera Aguilar, D.; Podhorzer, A.; Fuentes, F.; Corral Vazquez, C.; Guzman, M.; Giordano, M. N.; Trevani, A. S.; de Paiva, C. S.; Galletti, J. G.
10.1101/2024.03.22.586336 — immunology — Posted on 2024-09-15
2934 Intestinal helminth skews DC2 development towards regulatory phenotype to counter the anti-helminth immune response.
Andrusaite, A. T.; Ridgewell, O. J.; Ahlback, A. A.; Webster, H. C.; Yamaguchi, H.; Peel, M.; Frede, A.; Al-Khalidi, S. K.; Farthing, A.; Heawood, A. L.; Smith, A.; Roberts, E. W.; Mowat, A. M.; Maizels, R. M. M.; Perona-Wright, G.; Milling, S. W.
10.1101/2024.09.11.612410 — immunology — Posted on 2024-09-15
2937 Partial repair causes permanent defects in papillary structure and function after reversal of urinary obstruction
Vanichapol, T.; Gonzalez, A.; Delgado, R.; Brewer, M.; Clouthier, K.; Menshikh, A.; Snyder, W.; Raman, T.; Sander, V.; Davidson, A. J.; de Caestecker, M.
10.1101/2024.09.11.612436 — pathology — Posted on 2024-09-15
2940 Dynamics of the adhesion complex of the human pathogens Mycoplasma pneumoniae and Mycoplasma genitalium
Kawamoto, A.; Vizarraga, D.; Marcos-Silva, M.; Martin, J.; Makino, F.; Miyata, T.; Roel, J.; Marcos, E.; Pich, O. Q.; Aparicio, D.; Fita, I.; Miyata, M.; Pinol, J.; Namba, K.; Kenri, T.
10.1101/2023.07.31.551205 — molecular biology — Posted on 2024-09-15
2943 Sensation is Dispensable for the Maturation of the Vestibulo-ocular Reflex
Leary, P.; Bellegarda, C.; Quainoo, C.; Goldblatt, D.; Rosti, B.; Schoppik, D.
10.1101/2024.05.17.594732 — neuroscience — Posted on 2024-09-15
2945 Vaginal Tissue Engineering via Gelatin-Elastin Fiber-Reinforced Hydrogels
Zambuto, S. G.; Kolluru, S. S.; Hamdaoui, A.; Mascot, A. M.; Sutcliffe, S. S.; Lowder, J. L.; Oyen, M. L.
10.1101/2024.09.09.611932 — bioengineering — Posted on 2024-09-15
2946 Improving genomic selection in hexaploid wheat with sub-genome additive and epistatic models
Tessele, A.; Gonzalez-Dieguez, D. O.; Crossa, J.; Johnson, B. E.; Morris, G. P.; Fritz, A. K.
10.1101/2024.04.19.590350 — genetics — Posted on 2024-09-15
2948 PIP5K-Ras bistability initiates plasma membrane symmetry breaking to regulate cell polarity and migration
Deng, Y.; Banerjee, T.; Pal, D. S.; Banerjee, P.; Zhan, H. D.; Borleis, J.; Iglesias, P. A.; Devreotes, P.
10.1101/2024.09.15.613115 — cell biology — Posted on 2024-09-15
2951 De novo Design of A Fusion Protein Tool for GPCR Research
Gao, K.; Zhang, X.; Nie, J.; Meng, H.; Zhang, W.; Tian, B.; Liu, X.
10.1101/2024.09.14.613090 — biophysics — Posted on 2024-09-15
2953 Synaptonemal complex protects double-Holliday junctions during meiosis
Tang, S. M.; Koo, J.; Pourhosseinzadeh, M.; Nguyen, E.; Liu, N.; Ma, C.; Lu, H.; Lee, M.; Hunter, N.
10.1101/2024.09.14.613089 — cell biology — Posted on 2024-09-15
2958 Exploiting correlations across trials and behavioral sessions to improve neural decoding
Zhang, Y.; Lyu, H.; Hurwitz, C.; Wang, S.; Findling, C. L.; Hubert, F.; Pouget, A.; International Brain Laboratory, ; Varol, E.; Paninski, L.
10.1101/2024.09.14.613047 — neuroscience — Posted on 2024-09-15
2959 Evaluating and Comparing Measures of Aperiodic Neural Activity
Donoghue, T.; Hammonds, R.; Lybrand, E.; Waschke, L.; Gao, R.; Voytek, B.
10.1101/2024.09.15.613114 — neuroscience — Posted on 2024-09-15
2960 Sleep-wake states are encoded across emotion-regulation regions of the mouse brain
Walder-Christensen, K.; Goffinet, J.; Bey, A.; Syed, R.; Benton, J.; Mague, S.; Adamson, E.; Vera, D.; Soliman, H.; Kansagr, S.; Carlson, D.; Dzirasa, K.
10.1101/2024.09.15.613104 — neuroscience — Posted on 2024-09-15
2961 Megabouts: a flexible pipeline for zebrafish locomotion analysis
Jouary, A.; Laborde, A.; Silva, P. T.; Mata, J. M.; Marques, J. C.; Collins, E.; Peterson, R. T.; Machens, C. K.; Orger, M. B.
10.1101/2024.09.14.613078 — animal behavior and cognition — Posted on 2024-09-15
2962 Modality specific memory enhancement in Heliconius butterflies
Hodge, E.; Alcalde Anton, A.; Bestea, L.; Hernandez, G.; Aguilar, J. M.; Farnworth, M. S.; Dell'Aglio, D. D.; McMillan, W. O.; Montgomery, S. H.
10.1101/2024.09.14.612954 — animal behavior and cognition — Posted on 2024-09-15
2963 Immune-like glycan-sensing and horizontally-acquired glycan-processing orchestrate host control in a microbial endosymbiosis
Jenkins, B. H.; Kilias, E. S.; Savory, F. R.; Soerensen, M. E. S.; Poirier, C.; Attah, V.; Drew, G. C.; Blagrave, J.; Galindo, L. J.; Leonard, G.; Cameron, D. D.; Brockhurst, M. A.; Milner, D. S.; Richards, T. A.
10.1101/2024.09.14.613017 — evolutionary biology — Posted on 2024-09-15
2964 Co-transcriptional RNA processing boosts zygotic gene activation
Xu, J.; Li, X.; Hao, X.; Hu, X.; Ma, S.; Hong, Y.; Zhang, J.; Yan, D.; Deng, H.; Na, J.; Ji, X.; Chang, Z.; Shen, X.
10.1101/2024.09.14.613088 — developmental biology — Posted on 2024-09-15
2965 An anatomical investigation of alkaptonuria: Novel insights into ochronosis of cartilage and bone
Hughes, J. H.; Charlesworth, G.; Prior, A.; Tierney, C. M.; Rothwell, P. D.; Thomas, N. P.; Ranganath, L. R.; Gallagher, J. A.; Bond, A. P.
10.1101/2024.09.11.612405 — pathology — Posted on 2024-09-15
2969 Not so selfish: transposable elements fuel adaptation to climate change
Potapenko, E. V.; Schwartz, D.; Mandel, T.; Ashkenazy, N.; Fuerst, D.; Atsmon, G.; Korol, A. B.; Kantar, M. B.; Bar-Massada, A.; Hubner, S.
10.1101/2024.09.02.610836 — evolutionary biology — Posted on 2024-09-15
2971 ARHGEF3 Regulates Hair Follicle Morphogenesis
Kalyanakrishnan, K.; Beaudin, A.; Jette, A.; Ghezelbash, S.; Ioana Hotea, D.; Chen, J.; Lefrancois, P.; Laurin, M.
10.1101/2024.09.13.612256 — developmental biology — Posted on 2024-09-15
2973 Integrative determination of the atomic structure of mutant huntingtin exon 1 fibrils implicated in Huntington's disease
Bagherpoor Helabad, M.; Matlahov, I.; Kumar, R.; Daldrop, J. O.; Jain, G.; Weingarth, M.; van der Wel, P. C. A.; Miettinen, M. S.
10.1101/2023.07.21.549993 — molecular biology — Posted on 2024-09-15
2975 Representational dissimilarity component analysis (ReDisCA)
Ossadtchi, A.; Semenkov, I.; Zhuravleva, A.; Kozunov, V.; Serikov, O.; Voloshina, E.
10.1101/2024.02.01.578343 — neuroscience — Posted on 2024-09-15
2976 Glymphatic clearance is enhanced during sleep
Kroesbergen, E.; Riesselmann, L. V.; Gomolka, R. S.; Pla, V.; Esmail, T.; Stenmo, V. H.; Kovacs, E. R.; Nielsen, E. S.; Goldman, S. A.; Nedergaard, M.; Weikop, P.; Mori, Y.
10.1101/2024.08.24.609514 — neuroscience — Posted on 2024-09-15
2978 The new phycobilisome linker protein ApcI regulates high light adaptation in Synechocystis sp. PCC 6803
Espinoza-Corral, R.; Zavrel, T.; Sutter, M.; Leslie, C. H.; Yang, K.; Beck, W. F.; Cerveny, J.; Kerfeld, C. A.
10.1101/2024.09.09.612062 — plant biology — Posted on 2024-09-15
2979 MITF Targets in Gastrointestinal Stromal Tumors: Implication in Autophagy and Extracellular Vesicle Secretion
Proano-Perez, E.; Serrano-Candelas, E.; Guerrero, M.; Gomez-Peregrina, D.; Llorens, C.; Soriano, B.; Gamez-Valero, A.; Herrero-Lorenzo, M.; Marti, E.; Serrano, C.; Martin, M.
10.1101/2024.09.10.612253 — cancer biology — Posted on 2024-09-15
2980 TopBP1 biomolecular condensates: a new therapeutic target in advanced-stage colorectal cancer.
Morano, L.; Vie, N.; Aissanou, A.; Egger, T.; Aze, A.; Fiachetti, S.; Seitz, H.; Milazzo, L.-A.; GARAMBOIS, V.; Bonnefoy-Berard, N.; Gongora, C.; Constantinou, A.; Basbous, J.
10.1101/2024.09.10.612204 — cancer biology — Posted on 2024-09-15
2982 Assessing Aral Sea residual lake system: impact of fluctuating salinity on phytoplankton communities
Malashenkov, D. V.; Voros, L.; Duisen, A.; Dashkova, V.; Abilkas, A.; Vorobjev, I. A.; Barteneva, N. S.
10.1101/2024.09.08.611860 — ecology — Posted on 2024-09-15
2983 Microglia-specific NF-κB signaling is a critical regulator of prion-induced glial inflammation and neuronal loss
Hay, A. J. D.; Popichak, K. A.; Mumford, G.; Shirley, P.; Bian, J.; Wolfrath, L.; Lei, S. S.; Eggers, M.; Nicholson, E. M.; Tjalkens, R. B.; Zabel, M. D.; Moreno, J. A.
10.1101/2024.09.12.612597 — molecular biology — Posted on 2024-09-15
2984 A Novel Rapid Host Cell Entry Pathway Determines Intracellular Fate of Staphylococcus aureus
Rühling, M.; Schmelz, F.; Ulbrich, K.; Wolf, J.; Pfefferle, M.; Moldovan, A.; Knoch, N.; Iwanowitsch, A.; Kappe, C.; Paprotka, K.; Arenz, C.; Fraunholz, M. J.
10.1101/2024.09.13.612871 — microbiology — Posted on 2024-09-15
2985 Single-cell analysis of human airway epithelium identifies cell type-specific responses to Aspergillus and Coccidioides
Harding, A. T.; Crossen, A. J.; Reedy, J. L.; Basham, K. J.; Hepworth, O. W.; Zhang, Y.; Shah, V. S.; Brown Harding, H.; Surve, M. V.; Simaku, P.; Kwaku, G. N.; Nolling Jensen, K.; Otto, Y.; Ward, R. A.; Thompson, G. R.; Klein, B. S.; Rajagopal, J.; Sen, P.; Haber, A. L.; Vyas, J. M.
10.1101/2024.09.09.612147 — immunology — Posted on 2024-09-15
2986 A brainstem circuit controls cough-like airway defensive behaviors in mice
Xu, X.; Nie, X.; Zhang, W.; Jiang, H.-H.; Liu, B.; Ren, Y.; Wang, T.; Xu, X.; Yang, J.; Luo, F.
10.1101/2024.09.08.611924 — neuroscience — Posted on 2024-09-15
2987 Attentional Information Routing in The Human Brain
Boroujeni, K. B.; Helfrich, R. F.; Fiebelkorn, I. C.; Bentley, N.; Lin, J. J.; Knight, R. T.; Kastner, S.
10.1101/2024.09.11.612548 — neuroscience — Posted on 2024-09-15
2988 Cryo-EM Structure of Phospholipase Cϵ Defines N-terminal Domains and their Roles in Activity
Samassekou, K.; Garland-Kuntz, E. E.; Ohri, V.; Fisher, I. J.; Erramilli, S. K.; Muralidharan, K.; Bogdan, L. M.; Gick, A. M.; Kossiakoff, A. A.; Lyon, A. M.
10.1101/2024.09.11.612521 — biochemistry — Posted on 2024-09-15
2992 Identification of Proteins Influencing CRISPR-Associated Transposases for Enhanced Genome Editing
Song, L.; Alker, A. T. P.; Oromi-Bosch, A.; Swartz, S. E.; Martinson, J. N. V.; Arora, J.; Wang, A. M.; Rovinsky, R.; Smith, S. J.; Pierce, E. C.; Deutschbauer, A. M.; Doudna, J. A.; Cress, B. F.; Rubin, B. E.
10.1101/2024.09.11.612086 — microbiology — Posted on 2024-09-15
2993 Mitochondrial Hyperactivity and Reactive Oxygen Species Drive Innate Immunity to the Yellow Fever Virus-17D Live-Attenuated Vaccine
Muccilli, S. G.; Schwarz, B.; Jessop, F.; Shannon, J. G.; Bohrnsen, E.; Shue, B.; Hong, S.-H.; Hsu, T.; Ashbrook, A. W.; Guarnieri, J. W.; Lack, J.; Wallace, D. C.; Bosio, C. M.; MacDonald, M. R.; Rice, C. M.; Yewdell, J. W.; Best, S. M.
10.1101/2024.09.04.611167 — immunology — Posted on 2024-09-15
2996 GBA1 mutations alter neuronal firing and structure, regulating VGLUT2 and CRYAB in dopamine neurons
Rodriguez-Traver, E.; Suarez, L. M.; Crespo, C.; Gonzalez-Burgos, I.; Vecino, R.; Jurado-Coronel, J. C.; Galan, M.; Gonzalez-Gonzalez, M.; Moratalla, R.; Vicario, C.
10.1101/2024.08.05.606574 — neuroscience — Posted on 2024-09-15
2998 Engineered yeast cells simulating CD19+ cancers to control CAR T cell activation
Deichmann, M.; Schiesaro, G.; Ramanathan, K.; Zeeberg, K. V. W.; Koefoed, N. M. T.; Ormhoj, M.; Friis, R. U. W.; Gill, R. T.; Hadrup, S. R.; Jensen, E. D.; Jensen, M. K.
10.1101/2023.10.25.563929 — synthetic biology — Posted on 2024-09-15
2999 Disruption of the PGE2 synthesis / response pathway restrains atherogenesis in programmed cell death-1 (Pd-1) deficient hyperlipidemic mice
Ricciotti, E.; Tang, S. Y.; Mrcela, A.; Das, U.; Lordan, R.; Joshi, R.; Ghosh, S.; Aoyama, J.; McConnell, R.; Yang, J.; Grant, G. R.; FitzGerald, G. A.
10.1101/2024.07.02.601762 — pharmacology and toxicology — Posted on 2024-09-15
3000 Evolutionarily diverse caveolins share a common structural framework built around amphipathic discs
Han, B.; Connolly, S.; Wilson, L. F. L.; Schultz, D. T.; Gulsevin, A.; Meiler, J.; Karakas, E.; Ohi, M. D.; Kenworthy, A. K.
10.1101/2022.11.15.516482 — biophysics — Posted on 2024-09-15
3001 Inkjet-printed graphene multielectrode arrays: an accessible platform for in vitro cardiac electrophysiology
Lumpuy-Castillo, J.; Fu, Y.; Avila, A.; Solodka, K.; Li, J.; Lorenzo, O.; Zeglio, E.; Garma, L. D.
10.1101/2024.09.09.611887 — bioengineering — Posted on 2024-09-15
3004 Distinct and interdependent functions of three RING proteins regulate recombination during mammalian meiosis
Ito, M.; Yun, Y.; Kulkarni, D. S.; Sandhu, S.; Nunez, B.; Hu, L.; Lee, K.; Lim, N.; Hirota, R.; Prendergast, R.; Huang, C.; Huang, I.; Hunter, N.
10.1101/2023.11.07.566091 — genetics — Posted on 2024-09-15
3005 'Mitotic' kinesin-5 is a dynamic brake for axonal growth
Lu, W.; Lee, B. S.; Deng, H.; Lakonishok, M.; Martin-Blanco, E.; Gelfand, V. I.
10.1101/2024.09.12.612721 — cell biology — Posted on 2024-09-15
3009 Age-related decline of PKA-RIIβ level in SNc dopaminergic neurons underlies PD pathogenesis
Zhao, Y.; Wang, B.; Zhao, M.; Liu, J.; Hou, Y.; Wei, S.; Xiong, C.; Li, D.; Zheng, R.
10.1101/2024.09.13.612981 — neuroscience — Posted on 2024-09-15
3011 Combined transcriptomic, connectivity, and activity profiling of the medial amygdala using highly amplified multiplexed in situ hybridization (hamFISH)
Edwards, M. D.; Yin, Z.; Sueda, R.; Gubanova, A.; Xu, C. S.; Lakner, V.; Murchie, M.; Lee, C.-Y.; Ng, K.; Farrell, K.; Faraway, R.; Ganguly, S.; Jacobs, E.; Bintu, B.; Isogai, Y.
10.1101/2024.09.14.613026 — neuroscience — Posted on 2024-09-15
3012 Contribution of amygdala to dynamic model arbitration under uncertainty
Woo, J. H.; Costa, V. D.; Taswell, C. A.; Rothenhoefer, K. M.; Averbeck, B.; Soltani, A.
10.1101/2024.09.13.612869 — neuroscience — Posted on 2024-09-15
3016 Neurovascular Impulse Response Function (IRF) during spontaneous activity differentially reflects intrinsic neuromodulation across cortical regions
Rauscher, B. C.; Fomin-Thunemann, N.; Kura, S.; Doran, P. R.; Perez, P. D.; Kılıc, K.; Martin, E. A.; Balog, D.; Chai, N. X.; Froio, F. A.; Bloniasz, P. F.; Herrema, K. E.; Tang, R.; Knudstrup, S. G.; Garcia, A.; Jiang, J. X.; Gavornik, J. P.; Kleinfeld, D.; Hasselmo, M. E.; Lewis, L. D.; Sakadzic, S.; Tian, L.; Mishne, G.; Stephen, E. P.; Thunemann, M.; Boas, D. A.; Devor, A.
10.1101/2024.09.14.612514 — neuroscience — Posted on 2024-09-15
3017 Mindfulness-based Neurofeedback: A Systematic Review of EEG and fMRI studies
Treves, I. N.; Greene, K. D.; Bajwa, Z.; Wool, E.; Kim, N.; Bauer, C. C.; Bloom, P. A.; Pagliaccio, D.; Zhang, J.; Whitfield-Gabrieli, S.; Auerbach, R. P.
10.1101/2024.09.12.612669 — neuroscience — Posted on 2024-09-15
3018 Muscle spindles provide flexible sensory feedback for movement sequences
Olson, W. P.; Chokshi, V. B.; Kim, J. J.; Cowan, N.; O'Connor, D. H.
10.1101/2024.09.13.612899 — neuroscience — Posted on 2024-09-15
3019 Pervasive findings of directional selection realize the promise of ancient DNA to elucidate human adaptation
Akbari, A.; Barton, A. R.; Gazal, S.; Li, Z.; Kariminejad, M.; Perry, A.; Zeng, Y.; Mittnik, A.; Patterson, N.; Mah, M.; Zhou, X.; Price, A. L.; Lander, E. S.; Pinhasi, R.; Rohland, N.; Mallick, S.; Reich, D.
10.1101/2024.09.14.613021 — evolutionary biology — Posted on 2024-09-15
3020 The Drosophila Estrogen-Related Receptor promotes triglyceride storage within the larval fat body
Fasteen, T. D.; Hernandez, M. R.; Policastro, R. A.; Sterrett, M. C.; Zentner, G. E.; Tennessen, J. M.
10.1101/2024.09.13.612925 — developmental biology — Posted on 2024-09-15
3027 Cross-sectional brain age assessments are limited in predicting future brain change
Korbmacher, M.; Vidal-Pineiro, D.; Wang, M.-Y.; van der Meer, D.; Wolfers, T.; Nakua, H.; Eikefjord, E.; Andreassen, O.; Westlye, L. T.; Maximov, I. I.
10.1101/2024.09.11.612523 — neuroscience — Posted on 2024-09-15
3028 Isotonic and minimally invasive optical clearing media for live cell imaging ex vivo and in vivo
Inagaki, S.; Nakagawa-Tamagawa, N.; Huynh, N.; Kambe, Y.; Yagasaki, R.; Manita, S.; Fujimoto, S.; Noda, T.; Mori, M.; Teranishi, A.; Takeshima, H.; Naito, Y.; Yokoyama, T.; Sakamoto, M.; Hayashi, K.; Kitamura, K.; Tagawa, Y.; Okuda, S.; Sato, T.; Imai, T.
10.1101/2024.09.13.612584 — neuroscience — Posted on 2024-09-15
3036 Abnormal mu rhythm state-related cortical and corticospinal responses in chronic stroke
Wischnewski, M.; Haigh, Z. J.; Berger, T.; Rotteveel, J.; Van Oijen, T.; Perera, N. D.; Shirinpour, S.; Alekseichuk, I.; Hawe, R. L.; Opitz, A.
10.1101/2024.09.12.612604 — neuroscience — Posted on 2024-09-15
3040 AAV-mediated expression of proneural factors stimulates neurogenesis from adult Müller glia in vivo.
Pavlou, M.; Probst, M.; Filippova, E.; Kaplan, L.; Prieve, A. R.; Rieke, F.; Reh, T. A.
10.1101/2024.09.13.612930 — neuroscience — Posted on 2024-09-15
3042 Early intrinsic plasticity of ACC engram neurons defines memory formation and precision
Hadzibegovic, S.; Zhu, L.; Ginger, M.; De Sa, R.; Le Corf, K.; Costa, M. J.; Nicole, O.; Bontempi, B.; Frick, A.
10.1101/2024.09.13.612936 — neuroscience — Posted on 2024-09-15
3044 Decreased GABA levels during development result in increased connectivity in the larval zebrafish tectum
Liu, Y.; Chen, Y.; Duffy, C. R.; VanLeuven, A. J.; Byers, J. B.; Schriever, H. C.; Ball, R. E.; Carpenter, J. M.; Gunderson, C. E.; Filipov, N. M.; Ma, P.; Kner, P.; Lauderdale, J. D.
10.1101/2024.09.11.612511 — neuroscience — Posted on 2024-09-15
3051 Deep learning for classifying neuronal morphologies: combining topological data analysis and graph neural networks
Kanari, L.; Schmidt, S.; Casalegno, F.; Delattre, E.; Banjac, J.; Negrello, T.; Shi, Y.; Meystre, J.; Defferrard, M.; Schurmann, F.; Markram, H.
10.1101/2024.09.13.612635 — neuroscience — Posted on 2024-09-15
3055 Data-driven determination of 1H-MRS basis set composition
Davies-Jenkins, C. W.; Zollner, H. J.; Simicic, D.; Alcicek, S.; Edden, R. A. E.; Oeltzschner, G.
10.1101/2024.09.11.612503 — neuroscience — Posted on 2024-09-15
3056 Cav3.1 is a leucine sensor in POMC neurons mediating appetite suppression and weight loss
Tsang, A. H.; Heeley, N.; Alcaino, C.; Hwang, E.; Lam, B. Y.; Rahman, T.; Darwish, T.; Nuzzaci, D.; Kay, R. G.; Sarkar, A.; Wang, R.; Basha, N.; Punnoose, A.; Kirwan, P.; Ma, M.; Yeo, G. S.; Merkle, F. T.; Gribble, F. M.; Reinmann, F.; Williams, K.; Blouet, C.
10.1101/2024.09.13.612843 — neuroscience — Posted on 2024-09-15
3059 Gene identification for ocular congenital cranial motor neuron disorders using human sequencing, zebrafish screening, and protein binding microarrays
Jurgens, J. A.; Ruiz, P. M. M.; King, J.; Foster, E. E.; Berube, L.; Chan, W.-M.; Barry, B. J.; Jeong, R.; Rothman, E.; Whitman, M. C.; MacKinnon, S.; Rivera-Quiles, C.; Pratt, B. M.; Easterbrooks, T.; Mensching, F. M.; Di Gioia, S. A.; Pais, L.; England, E. M.; de Berardinis, T.; Magli, A.; Koc, F.; Asakawa, K.; Kawakami, K.; O'Donnell-Luria, A.; Hunter, D. G.; Robson, C. D.; Bulyk, M. L.; Engle, E. C.
10.1101/2024.09.12.612713 — neuroscience — Posted on 2024-09-15
3062 Modelling coordinated nocturnal rhythms in ungulates
Ukrow, J.; Gubert, J.; Hahn-Klimroth, M.; Dierkes, P. W.; Schneider, G.
10.1101/2024.09.13.612804 — animal behavior and cognition — Posted on 2024-09-15
3064 Enhancer adoption by an LTR retrotransposongenerates viral-like particles causingdevelopmental limb phenotypes
Glaser, J.; Cova, G.; Fauler, B.; Prada-Medina, C.; Stanislas, V.; Phan, M. H. Q.; Schopflin, R.; Aktas, Y.; Franke, M.; Andrey, G.; Paliou, C.; Laupert, V.; Chan, W.-L.; Wittler, L.; Mielke, T.; Mundlos, S.
10.1101/2024.09.13.612906 — developmental biology — Posted on 2024-09-15
3066 The microbiota extends the reproductive lifespan by safeguarding the ovarian reserve
Munyoki, S. K.; Goff, J. P.; Reshke, A.; Wilderoter, E.; Mafarachisi, N.; Kolobaric, A.; Sheng, Y.; Mullett, S.; King, G.; DeSchepper, J.; Bookser, R.; Castro, C. A.; Gelhaus, S.; Grizotte-Lake, M.; Morrison, K. E.; Zeleznik, A. J.; Hand, T. W.; Brieno-Enriquez, M.; Jasarevic, E.
10.1101/2024.09.13.612929 — developmental biology — Posted on 2024-09-15
3067 Vibrotactile auricular vagus nerve stimulation alters limbic system connectivity in humans: A pilot study
Donovan, K. M.; Adams, J. D.; Park, K. Y.; Demarest, P.; Tan, G.; Willie, J. T.; Brunner, P.; Gorlewicz, J. L.; Leuthardt, E. C.
10.1101/2024.09.10.612366 — neuroscience — Posted on 2024-09-14
3072 Biomimetic Virus-Like Particles to control cell functions
Maayouf, H.; Dos Santos, T.; Boche, A.; Hedna, R.; Tars, K.; Brigaud, I.; Petithory, T.; Carreiras, F.; Arnold, C.; Lambert, A.; Pieuchot, L.
10.1101/2024.09.14.612851 — bioengineering — Posted on 2024-09-14
3076 Protonation/deprotonation-driven switch for the redox stability of low-potential ferredoxin
Wada, K.; Kobayashi, K.; Era, I.; Isobe, Y.; Kamimura, T.; Marukawa, M.; Nagae, T.; Honjo, K.; Kaseda, N.; Motoyama, Y.; Inoue, K.; Sugishima, M.; Kusaka, K.; Yano, N.; Fukuyama, K.; Mishima, M.; Kitagawa, Y.; Unno, M.
10.1101/2024.09.12.612615 — biochemistry — Posted on 2024-09-14
3077 Machine learning-augmented molecular dynamics simulations (MD) reveal insights into the disconnect between affinity and activation of ZTPriboswitch ligands
Fullenkamp, C. R.; Medhi, S.; Jones, C. P.; Tenney, L.; Pichling, P.; Prestwood, P.; Ferre-D'Amare, A.; Tiwary, P. S.; Schneekloth, J. S.
10.1101/2024.09.13.612887 — biochemistry — Posted on 2024-09-14
3078 Structures of aberrant spliceosome intermediates on their way to disassembly
Soni, K.; Horvath, A.; Dybkov, O.; Schwan, M.; Trakansuebkul, S.; Flemming, D.; Wild, K.; Urlaub, H.; Fischer, T.; Sinning, I.
10.1101/2024.09.13.612651 — biochemistry — Posted on 2024-09-14
3079 Mitochondrial Fatty Acid Oxidation is Stimulated by Red Light Irradiation
Herrera, M. A.; Caldeira da Silva, C. C.; Baptista, M. S.; Kowaltowski, A. J.
10.1101/2024.09.12.612633 — biochemistry — Posted on 2024-09-14
3089 Surface-mediated Bacteriophage Defense Incurs Fitness Tradeoffs for Interbacterial Antagonism
Tsai, C.-E.; Wang, F.-Q.; Yang, C.-W.; Yang, L.-L.; Chen, Y.-C.; Chen, P.-Y.; Hwang, I.-S.; Ting, S.-Y.
10.1101/2024.09.13.612980 — microbiology — Posted on 2024-09-14
3090 Utilization and degradation of laminarin-based substrates by marine yeasts suggests their niche-specific role in microbial loop dynamics.
Reich, M.; Arslan-Gatz, B.; Schultz-Johansen, M.; Hollwedel, T.-N.; Niggemeier, S.; Nimzyk, R.; Wichels, A.; Gerdts, G.; Hehemann, J.-H.; Harder, T.
10.1101/2024.09.13.612705 — microbiology — Posted on 2024-09-14
3091 Soil redox drives virus-host community dynamics and plant biomass degradation in tropical rainforest soils
Trubl, G.; Leleiwi, I.; Campbell, A.; Kimbrel, J. A.; Bhattacharyya, A.; Riley, R.; Malmstrom, R. R.; Blazewicz, S. J.; Pett-Ridge, J.
10.1101/2024.09.13.612973 — microbiology — Posted on 2024-09-14
3098 ARHGEF3 Regulates Hair Follicle Morphogenesis
Laurin, M.; Kalyanakrishnan, K.; Beaudin, A.; Jette, A.; Ghezelbash, S.; Ioana Hotea, D.; Chen, J.; Lefrancois, P.
10.1101/2024.09.13.612256 — developmental biology — Posted on 2024-09-14
3100 Predicting Task Activation Maps from Resting-State Functional Connectivity using Deep Learning
Madsen, S. J.; Uddin, L. Q.; Mumford, J. A.; Barch, D. M.; Fair, D. A.; Gotlib, I. H.; Poldrack, R. A.; Kuceyeski, A.; Saggar, M.
10.1101/2024.09.10.612309 — neuroscience — Posted on 2024-09-14
3101 Metastatic tumor cells in bone marrow differ from paired neuroblastoma tumor and contain subsets with therapy-resistant characteristics
Hochheuser, C.; Boltjes, A.; Keller, K. M.; Tol, S.; van de Mheen, M.; Pita Barros, C.; van Gestel-Fadaie, Z.; van Kuilenburg, A. B. P.; van Hooff, S.; Voermans, C.; Molenaar, J. J.; Tytgat, G. A. M.; Timmerman, I.
10.1101/2024.09.13.612231 — cancer biology — Posted on 2024-09-14
3103 BST2 induces vascular smooth muscle cell plasticity and phenotype switching during cancer progression
Bell, C.; Baylis, R.; Lopez, N.; Ma, W. F.; Gao, H.; Wang, F.; Bamezai, S.; Fu, C.; Kojima, Y.; Adkar, S.; Luo, L.; Miller, C.; Leeper, N. L.
10.1101/2024.09.10.612298 — cancer biology — Posted on 2024-09-14
3106 A high-throughput phenotypic screen combined with an ultra-large-scale deep learning-based virtual screening reveals novel scaffolds of antibacterial compounds
Scalia, G.; Rutherford, S. T.; Lu, Z.; Buchholz, K. R.; Skelton, N.; Chuang, K.; Diamant, N.; Huetter, J.-C.; Luescher, J.; Miu, A.; Blaney, J.; Gendelev, L.; Skippington, E.; Zynda, G.; Dickson, N.; Koziarski, M.; Bengio, Y.; Regev, A.; Tan, M.-W.; Biancalani, T.
10.1101/2024.09.11.612340 — bioinformatics — Posted on 2024-09-14
3107 SVbyEye: A visual tool to characterize structural variation among whole genome assemblies
Porubsky, D.; Guitart, X.; Yoo, D.; Dishuck, P. C.; Harvey, W. T.; Eichler, E. E.
10.1101/2024.09.11.612418 — bioinformatics — Posted on 2024-09-14
3111 The level of endothelial glycocalyx maturity modulates interactions with charged nano-materials
Bridges, C.; Fu, L.; Yeow, J.; Huang, X.; Jackson, M.; Kuchel, R.; Sterling, J.; Baker, S.; Lord, M.
10.1101/2024.09.10.611831 — bioengineering — Posted on 2024-09-14
3112 DiatOmicBase, a gene-centered platform to mine functional omics data across diatom genomes
Villar, E.; Zweig, N.; Vincens, P.; Cruz de Carvalho, H.; Duchene, C.; Liu, S.; Monteil, R.; Dorrell, R. G.; Fabris, M.; Vandepoele, K.; Bowler, C.; Falciatore, A.
10.1101/2024.09.12.612655 — genomics — Posted on 2024-09-14
3113 Haplotype-resolved assemblies provide insights into genomic makeup of the oldest grapevine cultivar (Munage) in Xingjiang
Zhong, H.; Shi, x.; Zhang, F.; Wang, X.; yadav, v.; Zhou, X.; Cao, s.; Zhang, S.; Zhang, C.; Qiao, J.; Liu, Z.; Zhang, y.; Liu, y.; Wang, H.; Xue, h.; Zhang, M.; Zhang, T.-H.; Zhou, Y.; Wu, X.; Xiao, H.
10.1101/2024.09.11.612401 — genomics — Posted on 2024-09-14
3114 LncRNA TAAL is a Modulator of Tie1-Mediated Vascular Function in Diabetic Retinopathy
Ranjan, G.; Arora, S.; Sharma, S.; Sharma, L.; Bhoyar, R. C.; Senthivel, V.; Scaria, V.; Chakrabarti, S.; Kaur, I.; Motiani, R. K.; Sivasubbu, S.
10.1101/2024.09.13.612383 — genetics — Posted on 2024-09-14
3115 EBAX-1/ZSWIM8 destabilizes miRNAs resulting in transgenerational memory of a predatory trait
Quiobe, S. P.; Kalirad, A.; Roeseler, W.; Witte, H.; Wang, Y.; Roedelsperger, C.; Sommer, R. J.
10.1101/2024.09.10.612280 — genetics — Posted on 2024-09-14
3116 The Draparnaldia genome: alternative mechanisms for multicellularity and terrestrialization in green plants
Caisova, L.; Crombez, E.; Arellano, M. S. T.; Gut, M.; Alioto, T. S.; Gomez-Garrido, J.; Dabad, M.; Esteve-Codina, A.; Petrik, I.; Pencik, A.; Novak, O.; Van de Peer, Y.; Vicoso, B.; Friml, J.
10.1101/2024.09.12.612648 — evolutionary biology — Posted on 2024-09-14
3119 SARS-CoV-2 protein ORF3a induces Atg8ylation of lysosomal membranes
Ajnar, D.; Sarkar, A.; Riyaz, S.; Menon, P.; Dutta, D.; Asati, P.; Sharma, P.; Pydi, S. P.; Kumar, S.
10.1101/2024.09.12.612614 — cell biology — Posted on 2024-09-14
3121 Islet amyloid disrupts MHC Class II antigen presentation and protects NOD mice from autoimmune diabetes.
Denroche, H. C.; Ng, V.; Velghe, J.; Suen, I.; Stanley, L.; Nackiewicz, D.; Komba, M.; Chen, S.; Soukhatcheva, G.; Dai, L.; Verchere, C. B.
10.1101/2024.09.10.612362 — immunology — Posted on 2024-09-14
3122 Adult oligodendrogenesis gates arcuate neuronal glucose sensing through remodelling of the blood-hypothalamus barrier via ADAMTS4
Buller, S.; Staricoff, E.; Riches, C.; Tsang, A.; Josipovic, M.; Ikemura, K.; Opoku, G.; Sato, I.; Hirohata, S.; Stenzel, S.; Nayar, S.; Vega, M. R.; Hecksher-Sorensen, J.; Timmler, S.; Dowsett, G.; Lam, B.; Yeo, G. S. H.; Alonge, K. M.; Li, H.; Richardson, W. D.; Evans, M. L.; Blouet, C.
10.1101/2024.09.10.612227 — neuroscience — Posted on 2024-09-14
3123 Protective variant in PLCgamma2 mitigates Alzheimer's disease associated pathology via enhancing beneficial microglia functions
Takalo, M.; Jeskanen, H.; Rolova, T.; Kervinen, I.; Hellen, M.; Heikkinen, S.; Koivisto, H.; Jokivarsi, K.; Muller, S. A.; Koivumaki, E.-M.; Makinen, P.; Juopperi, S.-P.; Willman, R.-M.; Sinisalo, R.; Hoffman, D.; Jantti, H.; Peitz, M.; Fliessbach, K.; Kuulasmaa, T.; Natunen, T.; Kemppainen, S.; Poutiainen, P.; Leinonen, V.; Malm, T.; Martiskainen, H.; Ramirez, A.; Haapasalo, A.; Lichtenthaler, S. F.; Tanila, H.; Haass, C.; Rinne, J.; Koistinaho, J.; Hiltunen, M.
10.1101/2024.09.12.612207 — neuroscience — Posted on 2024-09-14
3124 Operant conditioning of cortical waves through a brain-machine interface
Dogadov, A.; Shulz, D. E.; Ferezou, I.; Ego-Stengel, V.; Estebanez, L.
10.1101/2024.09.10.612344 — neuroscience — Posted on 2024-09-14
3126 Influence of the Glymphatic System on α-Synuclein Propagation: Role of Aquaporin-4 and the Dystrophin-Associated Protein Complex
Lopes, D. M.; Llewellyn, S. K.; Bury, S. E.; Wang, J.; Wells, J. A.; Gegg, M.; Verona, G.; Lythgoe, M. F.; Harrison, I. F.
10.1101/2024.09.11.612272 — neuroscience — Posted on 2024-09-14
3127 Pathogenic microbiota disrupts the intact structure of cerebral organoids by altering energy metabolism
Isik, M.; Eylem, C. C.; Erdogan-Gover, K.; Aytar-Celik, P.; Enuh, B. M.; Emregul, E.; Cabuk, A.; Yildirim, Y.; Nemutlu, E.; Muotri, A. R.; Derkus, B.
10.1101/2024.09.11.612577 — neuroscience — Posted on 2024-09-14
3131 The preferential injury of outer renal medulla after ischemia-reperfusion relies on high oxidative metabolism
Arnoux, G.; Serre, J.; Verissimo, T.; Tihy, M.; Placier, S.; Verney, C.; Sangla, F.; Paolucci, D.; Fernandez, M.; de Seigneux, S.; Sgardello, S.; Naesens, M.; Hadchouel, J.; Feraille, E.; Khodo, S. N.; Galichon, P.; Legouis, D.
10.1101/2024.09.12.612245 — physiology — Posted on 2024-09-14
3135 Associations on the Fly, a new feature aiming to facilitate exploration of the Open Targets Platform evidence
Cruz-Castillo, C.; Fumis, L.; Mehta, C.; Martinez-Osorio, R. E.; Roldan-Romero, J. M.; Cornu, H.; Uniyal, P.; Solano-Roman, A.; Carmona, M.; Ochoa, D.; McDonagh, E. M.; Buniello, A.
10.1101/2024.09.10.612089 — bioinformatics — Posted on 2024-09-14
3136 Enantiomeric histidine-rich peptide coacervates enhance antigen delivery to T cells
Pramanik, U.; Das, A.; Brown, E. M.; Struckman, H. L.; Wang, H.; Stealey, S.; Sprunger, M. L.; Abdul, W.; Fascetti, J.; Mondal, J.; Silva, J. R.; Zustiak, S. P.; Jackrel, M. E.; Rudra, J. S.
10.1101/2024.09.10.612317 — bioengineering — Posted on 2024-09-14
3138 Rapid production of modified cattle and sheep from spermatid-like stem cells
Yang, L.; Di, A.; Song, L.; Liu, X.; Wu, D.; Wang, S.; Hao, Z.; Bu, L.; Bai, C.; Su, G.; Wei, Z.; Zhang, L.; Liu, Z.; Gao, S.; Li, G.
10.1101/2024.09.10.612264 — bioengineering — Posted on 2024-09-14
3139 Exploring American Elderberry Compounds for Antioxidant, Antiviral, and Antibacterial Properties Through High-Throughput Screening Assays Combined with Untargeted Metabolomics
Dwikarina, A.; Bayati, M.; Efrat, N.; Roy, A.; Lei, Z.; Ho, K.-V.; Sumner, L. W.; Thomas, A. L.; Applequist, W.; Michael Greenlief, M.; Townesmith, A.; Lin, C.-H.
10.1101/2024.09.13.611920 — biochemistry — Posted on 2024-09-14
3140 Subcellular Level Spatial Transcriptomics with PHOTON
Rajachandran, S.; Xu, Q.; Cao, Q.; Zhang, X.; Chen, F.; Mangiameli, S. M.; Chen, H.
10.1101/2024.09.10.612328 — genomics — Posted on 2024-09-14
3142 Ongoing evolution of Middle East Respiratory Syndrome Coronavirus, Kingdom of Saudi Arabia, 2023-2024
Hassan, A. M.; Mühlemann, B.; Al-Subhi, T. L.; Rodon, J.; El-Kafrawy, S. A.; Memish, Z.; Melchert, J.; Bleicker, T.; Mauno, T.; Perlman, S.; Zumla, A.; Jones, T. C.; Müller, M. A.; Corman, V. M.; Drosten, C.; Azhar, E. I.
10.1101/2024.09.12.612455 — evolutionary biology — Posted on 2024-09-14
3144 G-CSF and IL-6 drive myeloid dysregulation during severe viral infection
Kajihara, K.; Yan, D.; Seim, G.; Little-Hooy, H.; Kang, J.; Chen, C.; De Simone, M.; Delemarre, T.; Darmanis, S.; Shivram, H.; Bauer, R.; Rosenberger, C. M.; Kapadia, S.; Xu, M.; Reyes, M.
10.1101/2024.09.12.612764 — immunology — Posted on 2024-09-14
3145 Longitudinal trajectories of aperiodic EEG activity in early to middle childhood
Sacks, D. D.; Valdes, V.; Wilkinson, C. L.; Levin, A. R.; Nelson, C. A.; Enlow, M. B.
10.1101/2024.09.10.612049 — neuroscience — Posted on 2024-09-14
3148 Quantitative cytoarchitectural phenotyping of deparaffinized human brain tissues
Di Meo, D.; Sorelli, M.; Ramazzotti, J.; Cheli, F.; Bradley, S.; Perego, L.; Lorenzon, B.; Mazzamuto, G.; Emmi, A.; Porzionato, A.; De Caro, R.; Garbelli, R.; Biancheri, D.; Pelorosso, C.; Conti, V.; Guerrini, R.; Pavone, F. S.; Costantini, I.
10.1101/2024.09.10.612232 — neuroscience — Posted on 2024-09-14
3149 Reduction of RAD23A extends lifespan and mitigates pathology in TDP-43 mice
Xueshui, G. n.; Prajapati, R. n.; Chun, J. n.; Byun, I. n.; Gebis, K. K.; Wang, Y.-Z. n.; Ling, K. n.; Dalton, C. n.; Blair, J. A.; Hamidianjahromi, A. n.; Bachmann, G. n.; Rigo, F. n.; Jafar-nejad, P. n.; Savas, J. n.; Lee, M. J.; Sreedharan,, J. n.; Kalb, R.
10.1101/2024.09.10.612226 — neuroscience — Posted on 2024-09-14
3150 Platelet PI3Kβ regulates breast cancer metastasis
Graff, R. C.; Haimowitz, A.; Aguilan, J.; Levine, A.; Zhang, J.; Yuan, W.; Roose-Girma, M.; Seshagiri, S.; Porcelli, S. A.; Gamble, M. J.; Sidoli, S.; Bresnick, A. R.; Backer, J.
10.1101/2024.09.10.612261 — cancer biology — Posted on 2024-09-14
3154 High fidelity genetic markers for sexing Cannabis sativa seedlings
Prentout, D.; El Aoudati, S.; Mathis, F.; Marais, G.; Henri, H.
10.1101/2024.09.10.612257 — genomics — Posted on 2024-09-14
3156 Parechovirus-3 infection disrupts immunometabolism and leads to glutamate excitotoxicity in neural organoids
Capendale, P. E.; Ambikan, A. T.; Garcia Rodriguez, I.; Vieira de Sa, R.; Pajkrt, D.; Wolthers, K. C.; Neogi, U.; Sridhar, A.
10.1101/2024.09.10.611955 — neuroscience — Posted on 2024-09-14
3159 Aryl hydrocarbon receptor restricts axon regeneration of DRG neurons in response to injury
Halawani, D.; Wang, Y.; Estill, M.; Sefiani, A.; Ramakrishnan, A.; Li, J.; Ni, H.; Halperin, D.; Shen, L.; Geoffroy, C. G.; Friedel, R. H.; Zou, H.
10.1101/2023.11.04.565649 — neuroscience — Posted on 2024-09-14
3160 TAAR2-9 Knockout Mice Exhibit Reduced Wakefulness and Disrupted REM Sleep
Park, S.; Heu, J.; Scheldrup, G.; Tisdale, R.; Sun, Y.; Haire, M.; Ma, S.-C.; Hoener, M. C.; Kilduff, T. S.
10.1101/2024.09.09.612114 — neuroscience — Posted on 2024-09-14
3161 A brain-body feedback loop driving HPA-axis dysfunction in breast cancer
Gomez, A.; Wu, Y.; Zhang, C.; Boyd, L.; Wee, T. L.; Gewolb, J.; Amor, C.; Cheadle, L. M.; Borniger, J. C.
10.1101/2024.09.13.612923 — neuroscience — Posted on 2024-09-14
3165 Nanomedicines targeting signaling of protease-activated receptor 2 in organelles provide sustained analgesia
Teng, S. L.; Latorre, R.; Bhansali, D.; Lewis, P. K.; Pollard, R. E.; Peach, C. J.; Sokrat, B.; Thanigai, G. S. A.; Chiu, T.; Jensen, D. D.; Jimenez-Vargas, N. N.; Mocherniak, A.; Parreiras-E-Silva, L. T.; Bouvier, M.; Bogyo, M.; Gaspari, M. M.; Vanner, S. J.; Pinkerton, N. M.; Leong, K. W.; Schmidt, B. L.; Bunnett, N. W.
10.1101/2024.09.10.612022 — physiology — Posted on 2024-09-14
3166 Targeting the Schwann Cell EP2/cAMP Nanodomain to Block Pain but not Inflammation
Nassini, R.; Landini, L.; Marini, M.; Chieca, M.; Souza Monteiro de Araujo, D.; Montini, M.; Pensieri, P.; Abruzzese, V. D.; De Siena, G.; Zhang, J.; De Giorgi, V.; Romitelli, A.; Brancolini, G.; Tonello, R.; Peach, C. J.; Mastricci, A.; Scuffi, I.; Tesi, M.; Jensen, D. D.; Schmidt, B. L.; Bunnett, N. W.; De Logu, F.; Geppetti, P.
10.1101/2024.09.10.612200 — pharmacology and toxicology — Posted on 2024-09-14
3170 Catalytically distinct IDH1 mutants tune phenotype severity in tumor models
Adam, M. A. A.; Robinson, M.; Schwartz, A. V.; Wells, G. A.; Hoang, A.; Albekioni, E.; Gallo, C.; Chao, G.; Weeks, J.; Quichocho, G.; George, U. Z.; House, C. D.; Turcan, S.; Sohl, C. D.
10.1101/2024.04.22.590655 — genomics — Posted on 2024-09-14
3171 Gene regulatory dynamics during craniofacial development in a carnivorous marsupial
Cook, L. E.; Feigin, C. Y.; Hills, J.; Vespasiani, D. M.; Pask, A. J.; Gallego Romero, I.
10.1101/2023.02.13.528361 — developmental biology — Posted on 2024-09-14
3172 Unveiling the Intercompartmental Signaling Axis: Mitochondrial to ER Stress Response (MERSR) and its Impact on Proteostasis
Li, J. J.; Xin, N.; Yang, C.; Tavizon, L. A.; Hong, R.; Park, J.; Moore, T. I.; Tharyan, R. G.; Antebi, A.; Kim, H.-E.
10.1101/2023.09.07.556674 — cell biology — Posted on 2024-09-14
3174 CAMP: A modular metagenomics analysis system for integrated multi-step data exploration
Mak, L.; Tierney, B.; Ronkowski, C.; Brizola Toscan, R.; Turhan, B.; Toomey, M.; Martinez, J. S. A.; Fu, C.; Lucaci, A. G.; Barrios Solano, A. H.; Setubal, J. C.; Henriksen, J. R.; Zimmerman, S.; Kopbayeva, M.; Noyvert, A.; Iwan, Z.; Kar, S.; Nakazawa, N.; Meleshko, D.; Horyslavets, D.; Kantsypa, V.; Frolova, A.; Kahles, A.; Danko, D.; Elhaik, E.; Labaj, P.; Mason, C.; Hajirasouliha, I.
10.1101/2023.04.09.536171 — bioinformatics — Posted on 2024-09-14
3175 VACmap: An Accurate Long-Read Aligner for Unraveling Complex Genomic Rearrangements
Ding, H.; Sedlazeck, F. J.; Proukakis, C.; Morley, C.; Toffoli, M.; Schapira, A. H. V.; Liao, Z.; Pu, L.; Zhu, S.
10.1101/2023.08.03.551566 — bioinformatics — Posted on 2024-09-14
3176 Ventral-to-dorsal electrocyte development in electric organs of electric eel (Electrophorus).
Senarat, S.; Matsumoto, A.; Sakaki, S.; Tsuzuki, D.; Uchida, K.; Kuwahara, M.; Hondo, E.; Iida, A.
10.1101/2024.08.21.606117 — developmental biology — Posted on 2024-09-14
3177 Cnidaria XIAP activates caspase-mediated cell death
Chen, Y.; Wu, M.; Yuan, Z.; Wang, Q.; Xu, H.; Sun, L.
10.1101/2024.07.06.602363 — cell biology — Posted on 2024-09-14
3178 Stab Wound Injury Elicits Transit Amplifying Progenitor-like Phenotype in Parenchymal Astrocytes
Ninkovic, J.; Maddhesiya, P.; Koupourtidou, C.; Zambusi, A.; Novoselc, K. T.; Fischer-Sternjak, J.; Simon, T.; Olpe, C.; Jessberger, S.; Goetz, M.
10.1101/2024.09.10.612217 — neuroscience — Posted on 2024-09-14
3180 Kisspeptin fiber and receptor distribution analysis suggests its potential role in central sensorial processing and behavioral state control
Zhang, L.; Hernandez, V. S.; Zetter, M. A.; Hernandez-Perez, O. R.; Hernandez Gonzalez, R.; Camacho-Arroyo, I.; Eiden, L. E.; Millar, R. P.
10.1101/2023.09.05.556375 — neuroscience — Posted on 2024-09-14
3181 Competitive integration of time and reward explains value-sensitive foraging decisions and frontal cortex ramping dynamics
Bukwich, M.; Campbell, M. G.; Zoltowski, D.; Kingsbury, L.; Tomov, M. S.; Stern, J.; Kim, H. R.; Drugowitsch, J.; Linderman, S. W.; Uchida, N.
10.1101/2023.09.05.556267 — neuroscience — Posted on 2024-09-14
3182 Modulation of cortico-muscular coupling associated with split-belt locomotor adaptation
Oshima, A.; Yokoyama, H.; Kaneko, N.; Takahashi, R.; Takiyama, K.; Nakazawa, K.
10.1101/2024.09.09.612154 — neuroscience — Posted on 2024-09-14
3186 Sex-dependent effects of a high-fat diet on the hypothalamic response in mouse
Dreux, V.; Lefebvre, C.; Breemeersch, C.-E.; Salaun, C.; Bole-Feysot, C.; Guerin, C.; Dechelotte, P.; Goichon, A.; Coeffier, M.; Langlois, L. D.
10.1101/2024.09.10.612192 — neuroscience — Posted on 2024-09-14
3187 Unlocking expanded flagellin perception through rational receptor engineering
Li, T.; Bolanos, E. J.; Stevens, D.; Sha, H.; Prigozhin, D. M.; Coaker, G.
10.1101/2024.09.09.612155 — plant biology — Posted on 2024-09-14
3190 Renal cancer cells acquire immune surface protein through trogocytosis and horizontal gene transfer
Marcarian, H. Q.; Sivakoses, A.; Arias, A. M.; Ihedioha, O.; Bishop, M. C.; Lee, B. R.; Bothwell, A. L. M.
10.1101/2024.08.07.607036 — cancer biology — Posted on 2024-09-14
3192 NEK9 ablation rewires docetaxel resistance through induction of ERK-mediated cancer cell pyroptosis
Ansari, S. A.; Mohanty, S.; Mohapatra, P.; Rath, R.; Muduli, D.; Majumdar, S. K. D.; Swain, R. K.; Dash, R.
10.1101/2024.09.10.612209 — cancer biology — Posted on 2024-09-14
3193 Primary cilia promote EMT-induced triple-negative breast tumor heterogeneity and resistance to therapy
Tessier, C.; Derrien, J.; Dupuy, A.; Pele, T.; Moquet, M.; Roul, J.; Douillard, E.; El Harrif, C.; Pinson, X.; Le Gallo, M.; Godey, F.; Tas, P.; Viel, R.; Prigent, C.; Letouze, E.; Suzanne, P.; Dallemagne, P.; Campone, M.; Weinberg, R.; Lees, J.; Juin, P.; Guen, V.
10.1101/2024.09.10.612175 — cancer biology — Posted on 2024-09-14
3198 Fragle: Universal ctDNA quantification using deep learning of fragmentomic profiles
Jacobsen Skanderup, A.; Zhu, G.; Rahman, C.; Getty, V.; Baruah, P.; Carrie, H.; Lim, A.; Guo, Y. A.; Poh, Z.; Sim, N.; Abdelmoneim, A.; Cai, Y.; Lakshmanan, L.; Ho, D.; Thangaraju, S.; Poon, P.; Lau, Y.; Gan, A.; Ng, S.; Odinokov, D.; Koo, S.-L.; Chong, D.; Tay, B.; Tan, T.; Yap, Y.; Chok, A.; Ng, M.; Tan, P.; Tan, D.; Wong, L.; Wong, P.; Tan, I.
10.1101/2023.07.28.550922 — bioinformatics — Posted on 2024-09-14
3200 MIROSLAV: A complete open-source hardware and software toolkit for high-throughput circadian activity measurement and analysis in rodents
Virag, D.; Homolak, J.; Kodvanj, I.; Vargantolic, A.-M.; Babic Perhoc, A.; Meglic, P.; Sostaric Muzic, P.; Knezovic, A.; Osmanovic Barilar, J.; Cifrek, M.; Trkulja, V.; Salkovic-Petrisic, M.
10.1101/2024.06.25.600592 — animal behavior and cognition — Posted on 2024-09-14
3202 Sex-Specific DNA Methylation and Gene Expression Changes in Mouse Placentas After Early Preimplantation Alcohol Exposure
Legault, L.-M.; Dupas, T.; Breton-Larrivee, M.; Filion-Bienvenue, F.; Lemieux, A.; Langford-Avelar, A.; McGraw, S.
10.1101/2023.09.30.560198 — developmental biology — Posted on 2024-09-14
3204 Spatiotemporal recruitment of the ubiquitin-specific protease USP8 directs endosome maturation
Miao, Y.; Du, Y.; Wang, B.; Liang, J.; Liang, Y.; Dang, S.; Liu, J.; Li, D.; He, K.; Ding, M.
10.1101/2024.01.10.575034 — cell biology — Posted on 2024-09-14
3205 The T3SS structural and effector genes of Chlamydia trachomatis are expressed in distinct phenotypic cell forms.
Grieshaber, N.; Appa, C. R.; Ward, M.; Grossman, A.; McCormik, S.; Grieshaber, B. S.; Chiarelli, T. J.; Yang, H.; Omsland, A.; Grieshaber, S. S.
10.1101/2024.04.25.591156 — microbiology — Posted on 2024-09-14
3206 Epigenetic adaptation drives monocyte differentiation into microglia-like cells upon engraftment into the retina
Liu, J.; Lei, F.; Yan, B.; Cui, N.; Sharma, J.; Correa, V.; Roach, L.; Kikolaou, S.; Pitts, K.; Chodosh, J.; Maidana, D. E.; Vavvas, D. G.; Zhang, H.; Weitz, D.; Mostoslavsky, R.; Paschalis, E. I.
10.1101/2024.09.09.612126 — immunology — Posted on 2024-09-14
3207 GEARBOCS: An Adeno Associated Virus Tool for In Vivo Gene Editing in Astrocytes
Sivadasan Bindu, D.; Savage, J. T.; Brose, N.; Bradley, L.; Dimond, K.; Tan, C. X.; Eroglu, C.
10.1101/2023.01.17.524433 — neuroscience — Posted on 2024-09-14
3208 A double hit affecting the IKZF1-IKZF2 tandem in immune cells of schizophrenic patients regulate specific symptoms
Ballasch, I.; Lopez-Molina, L.; Galan-Ganga, M.; Sancho-Balsells, A.; Rodriguez-Navarro, I.; Borras-Pernas, S.; Rabadan, M.-A.; Chen, W.; Pasto-Pellicer, C.; Flotta, F.; Fernandez-Irigoyen, J.; Santamaria, E.; Aguilar, R.; Dobano, C.; Egri, N.; Hernandez, C.; Alfonso, M.; Juan, M.; Alberch, J.; del Toro, D.; Arranz, B.; Canals, J.-M.; Giralt, A.
10.1101/2024.09.09.612162 — neuroscience — Posted on 2024-09-14
3211 Ethograms reveal a fear conditioned visual cue to organize diverse behaviors in rats
Williams, D. C.; Chu, A.; Gordon, N. T.; DuBois, A. M.; Qian, S.; Valvo, G.; Shen, S.; Boyce, J. B.; Fitzpatrick, A. C.; Moaddab, M.; Russell, E. L.; Counsman, L. H.; McDannald, M. A.
10.1101/2024.09.10.612214 — neuroscience — Posted on 2024-09-14
3212 Direct piriform-to-auditory cortical projections shape auditory-olfactory integration
Vogler, N. W.; Chen, R.; Virkler, A.; Tu, V. Y.; Gottfried, J. A.; Geffen, M. N.
10.1101/2024.07.11.602976 — neuroscience — Posted on 2024-09-14
3215 SLC35G1: A highly chloride-sensitive transporter responsible for the basolateral membrane transport in intestinal citrate absorption
Mimura, Y.; Yasujima, T.; Inoue, K.; Akino, S.; Namba, C.; Kusuhara, H.; Sekiguchi, Y.; Ohta, K.; Yamashiro, T.; Yuasa, H.
10.1101/2024.04.29.591675 — physiology — Posted on 2024-09-14
3216 Acute sildenafil administration reduces susceptibility to induced atrial fibrillation in sheep
denham, N.; Madders, G. W.; Hutchings, D.; Smith, C. E.; Whitley, A.; Obeidat, M.; Trafford, A.; Pearman, C.; Dibb, K.
10.1101/2024.09.09.612118 — physiology — Posted on 2024-09-14
3218 Characterizing cell-type spatial relationships across length scales in spatially resolved omics data
dos Santos Peixoto, R.; Miller, B. F.; Brusko, M. A.; Aihara, G.; Atta, L.; Anant, M.; Atkinson, M. A.; Brusko, T. M.; Wasserfall, C. H.; Fan, J.
10.1101/2023.10.05.560733 — bioinformatics — Posted on 2024-09-14
3220 The interplay of DNA repair context with target sequence predictably biases Cas9-generated mutations
Pallaseni, A.; Peets, E. M.; Girling, G.; Crepaldi, L.; Kuzmin, I.; Moor, M.; Munoz-Subirana, N.; Schimmel, J.; Sercin, O.; Mardin, B. R.; Tijsterman, M.; Peterson, H.; Kosicki, M.; Parts, L.
10.1101/2023.06.28.546891 — genetics — Posted on 2024-09-14
3221 Evolutionary and Functional Analysis of Monoamine Oxidase C (MAO C): A Novel Member of the MAO Gene Family
Merello, G.; Olivares-Costa, M.; Basile, L.; Pastor, T. P.; Mendoza-Soto, P.; Padilla-Santiago, L.; Mardones, G.; Binda, C.; Opazo, J. C.
10.1101/2024.08.20.608864 — evolutionary biology — Posted on 2024-09-14
3222 TimberTracer: A Comprehensive Framework for the Evaluation of Carbon Sequestration by Forest Management and Substitution of Harvested Wood Products.
Boukhris, I.; Collalti, A.; Lahssini, S.; Dalmonech, D.; Nakhle, F.; Testolin, R.; Chiricao, M. V.; Santini, M.; Valentini, R.
10.1101/2024.01.24.576985 — ecology — Posted on 2024-09-14
3223 Peripheral positioning of lysosomes supports melanoma aggressiveness
Jerabkova-Roda, K.; Mousson, A.; Peralta, M.; Karali, R.; Justiniano, H.; Lisii, L.-M.; Carl, P.; Asokan, N.; Busnelli, I.; Larnicol, A.; Lefebvre, O.; Lachuer, H.; Pichot, A.; Stemmelen, T.; Molitor, A.; Hirschler, A.; Delalande, F.; Sick, E.; Carapito, R.; Carapito, C.; Hyenne, V.; Schauer, K.; Ronde, P.; GOETZ, J. G.; Scheid, L.; Lipsker, D.; Gros, F.; Frenger, Q.; Mittelheisser, V.; Bochler, L.; Bourgeat-Maudru, C.; Huang, K.-J.
10.1101/2023.07.07.548108 — cell biology — Posted on 2024-09-14
3224 Age-dependent Changes in a Chaperone Complex in the Mouse Heart
Bhat, P. D.; Nalli, A.; Shoemaker, L.; Kwong, J. Q.; Krishnamurthy, P.; Benian, G. M.
10.1101/2024.09.12.612759 — cell biology — Posted on 2024-09-14
3226 B cell receptor dependent enhancement of dengue virus infection
Gebo, C.; Hardy, C. S. C.; McElvany, B. D.; Graham, N. R.; Lu, J.; Moradpour, S.; Currier, J. R.; Friberg, H.; Gromowski, G. D.; Thomas, S. J.; Chan, G. J.; Diehl, S. A.; Waickman, A. T.
10.1101/2024.06.27.601099 — immunology — Posted on 2024-09-14
3229 Loss of Neurofibromin Induces Inflammatory Macrophage Phenotypic Switch and Retinal Neovascularization via GLUT1 Activation
ZAIDI, Y.; Tritz, R.; Zaidi, N.; Nabi, F.; Zaidi, S. A. H.; Morsy, A.; Harris, V.; Racine, R.; Hudson, F. Z.; Bordan, Z.; Kennard, S.; Batori, R.; Huo, Y.; Csanyi, G.; Belin de Chantemele, E. J.; Lei, K.; Boulis, N. M.; Fulton, D. J.; Khan, R. H.; Caldwell, R. B.; Stansfield, B. K.
10.1101/2024.09.13.612509 — cell biology — Posted on 2024-09-14
3230 Profiling the physiological impact of aberrant folded-state protein filamentation in cells
Levin, T.; Garcia-Seisdedos, H.; Lobov, A.; Wojtynek, M.; Alexandrov, A.; Jona, G.; Levi, D.; Medalia, O.; Levy, E. D.
10.1101/2024.09.13.612878 — cell biology — Posted on 2024-09-14
3233 A molecular switch for stress-induced activation of retrograde mitochondrial transport
Gladkova, C.; Paez-Segala, M. G.; Grant, W. P.; Myers, S. A.; Wang, Y.; Vale, R. D.
10.1101/2024.09.13.612963 — molecular biology — Posted on 2024-09-14
3235 Behavioral Evidence for Two Modes of Attention
Gupta, A.; Matthews, T.; Penhune, V. B.; Morillon, B.
10.1101/2024.09.12.612641 — neuroscience — Posted on 2024-09-14
3238 Pushing the limits of single molecule transcript sequencing to uncover the largest disease-associated transcript isoforms in the human neural retina
Stemerdink, M.; Riepe, T.; Zomer, N.; Salz, R.; Kwint, M.; Timmermans, R.; Ferrari, B.; Ferrari, S.; Duenas Rey, A.; Delanote, E.; de Bruijn, S. E.; Kremer, H.; Roosing, S.; Coppieters, F.; Hoischen, A.; Cremers, F. P. M.; 't Hoen, P. A. C.; van Wijk, E.; de Vrieze, E.
10.1101/2024.09.10.612265 — genetics — Posted on 2024-09-14
3242 Complex aneuploidy triggers autophagy and p53-mediated apoptosis and impairs the second lineage segregation in human preimplantation embryos
Regin, M.; Lei, Y.; De Deckersberg, E. C.; Janssens, C.; Huyghebaert, A.; Guns, Y.; Verdyck, P.; Verheyen, G.; Van de Velde, H.; Sermon, K.; Spits, C.
10.1101/2022.08.31.506009 — developmental biology — Posted on 2024-09-14
3243 Longitudinal Multi-omic Immune Profiling Reveals Age-Related Immune Cell Dynamics in Healthy Adults
Gong, Q.; Sharma, M.; Kuan, E. L.; Glass, M. C.; Chander, A.; Singh, M.; Graybuck, L. T.; Thomson, Z. J.; LaFrance, C. M.; Zaim, S. R.; Peng, T.; Okada, L. Y.; Genge, P. C.; Henderson, K. E.; Dornisch, E. M.; Layton, E. D.; Wittig, P. J.; Heubeck, A. T.; Mukuka, N. M.; Reading, J.; Roll, C. R.; Hernandez, V.; Parthasarathy, V.; Stuckey, T. J.; Musgrove, B.; Swanson, E.; Lord, C.; Weiss, M. D. A.; Phalen, C. G.; Mettey, R. R.; Lee, K. J.; Johanneson, J. B.; Kawelo, E. K.; Garber, J.; Krishnan, U.; Smithmeyer, M.; Wherry, E. J.; Vella, L.; Henrickson, S. E.; Kopp, M. S.; Savage, A. K.; Becker, L
10.1101/2024.09.10.612119 — immunology — Posted on 2024-09-14
3245 Preoptic area controls sleep-related seizure onset in a genetic epilepsy mouse model
Potesta, C. V.; Cargile, M. S.; Yan, A.; Xiong, S.; Macdonald, R. L.; Gallagher, M. J.; Zhou, C.
10.1101/2023.11.24.568593 — neuroscience — Posted on 2024-09-14
3246 Neural Evidence of Functional Compensation for Fluid Intelligence in Healthy Ageing
Knights, E.; Henson, R. N.; Morcom, A. M.; Mitchell, D. J.; Tsvetanov, K. A.
10.1101/2023.09.29.560099 — neuroscience — Posted on 2024-09-14
3247 The CHCHD2-CHCHD10 protein complex is modulated by mitochondrial dysfunction and alters lipid homeostasis in the mouse brain.
Gerlach, J.; Pireddu, P.; Zhang, X.; Wetzel, S.; Mennuni, M.; Milenkovic, D.; Nolte, H.; Branzell, N.; Kaya, I.; Villegas, R. G.; Rubalcava-Gracia, D.; Alsina, D.; Feederle, R.; Andren, P. E.; Langer, T.; Svenningsson, P.; Filograna, R.
10.1101/2024.09.10.612325 — neuroscience — Posted on 2024-09-14
3249 Savings in visuomotor learning is associated with connectivity changes within a cerebello-thalamo-cortical network encoding movement errors
Struber, L.; Lamalle, L.; Barraud, P.-A.; Courvoisier, A.; Rafael, L.; Ito, T.; Nougier, V.; Ostry, D. J.; Cignetti, F.
10.1101/2024.09.13.610754 — neuroscience — Posted on 2024-09-14
3250 Distinct basal ganglia decision dynamics under conflict and uncertainty
Ging-Jehli, N. R.; Cavanagh, J. F.; Ahn, M.; Segar, D. J. J.; Asaad, W. F.; Frank, M. J.
10.1101/2024.09.12.612658 — neuroscience — Posted on 2024-09-14
3253 Selective expansion of motor cortical projections in the evolution of vocal novelty
Isko, E. C.; Harpole, C. E.; Zheng, X. M.; Zhan, H.; Davis, M. B.; Zador, A. M.; Banerjee, A.
10.1101/2024.09.13.612752 — neuroscience — Posted on 2024-09-14
3256 Focused ultrasound enhanced antibody delivery for the treatment of Parkinson's Disease
Kwon, N.; Batts, A. J.; Zhang, H.; Lewis-Jackson, V.; Konofagou, E.; Przedborski, S.
10.1101/2024.09.13.611071 — neuroscience — Posted on 2024-09-14
3258 The G protein-coupled receptor TBXA2R activates ERMs to control cell motility and invasion of triple-negative breast cancer cells.
Leguay, K.; Naffati, O.; He, Y. Y.; Rogue, M.; Tesniere, C.; Gombos, M.; Kuasne, H.; Gaboury, L.; Le Gouill, C.; Meloche, S.; Bouvier, M.; Carreno, S.
10.1101/2023.03.28.534587 — cancer biology — Posted on 2024-09-14
3263 Unveiling multi-scale architectural features in single-cell Hi-C data using scCAFE
Wang, F.; Lin, J.; Alinejad-Rokny, H.; Ma, W.; Meng, L.; Huang, L.; Yu, J.; Chen, N.; Wang, Y.; Yao, Z.; Xie, W.; Li, X.; Wong, K.-C.
10.1101/2024.09.10.611762 — bioinformatics — Posted on 2024-09-14
3264 CNValidatron, automated validation of CNV calls using computer vision
Montalbano, S.; Walters, B.; Jonsson, G.; Gaadin, J.; Werge, T.; Stefansson, H.; Stefansson, K.; Ingason, A.
10.1101/2024.09.09.612035 — bioinformatics — Posted on 2024-09-14
3265 A Comparison of Tokenization Impact in AttentionBased and State Space Genomic Language Models
Lindsey, L. M.; Pershing, N. L.; Habib, A.; Stephens, W. Z.; Blaschke, A. J.; Sundar, H.
10.1101/2024.09.09.612081 — bioinformatics — Posted on 2024-09-14
3266 Proposing a methodology for axon-centric analysis of IOP-induced mechanical insult
Bansal, M.; Wang, B.; Waxman, S.; Zhong, F.; Hua, Y.; Lu, Y.; Reynaud, J.; Fortune, B.; Sigal, I. A.
10.1101/2024.09.09.611631 — bioengineering — Posted on 2024-09-14
3267 Solanum pan-genomics and pan-genetics reveal paralogs as contingencies in crop engineering
Benoit, M.; Jenike, K. M.; Satterlee, J. W.; Ramakrishnan, S.; Gentile, I.; Hendelman, A.; Passalacqua, M. J.; Suresh, H.; Shohat, H.; Robitaille, G. M.; Fitzgerald, B.; Alonge, M. M.; Wang, X.; Santos, R.; He, J.; Ou, S.; Golan, H.; Green, Y.; Swartwood, K.; Sierra, G. P.; Orejuela, A.; Fornaguera, F.; Goodwin, S.; McCombie, W. R.; Kizito, E. B.; Gagnon, E.; Knapp, S.; Sarkinen, T.; Frary, A.; Gillis, J.; Van Eck, J.; Schatz, M. C.; Lippman, Z. B.
10.1101/2024.09.10.612244 — genetics — Posted on 2024-09-14
3268 Comparative transcriptome and variant analyses of the pancreatic islets of a rat model of obese type 2 diabetes identifies a frequently distributed nonsense mutation in the lipocalin 2 gene
Yokoi, N.; Adachi, N.; Hirokoji, T.; Nakano, K.; Yoshihara, M.; Shigenaka, S.; Urakawa, R.; Taniguchi, Y.; Yoshida, Y.; Yokose, S.; Suyama, M.; Okamura, T.
10.1101/2024.09.13.609843 — genetics — Posted on 2024-09-14
3269 Extended Phenotype Influences Collective Behaviour and Survival in a Social Spider
Parthasarathy, B.; Shaikh, N. Y.; V, S. A.; C, V. S.; MV, S. K.; Dasu, K. K. V.
10.1101/2024.09.12.612246 — evolutionary biology — Posted on 2024-09-14
3270 No enhancement of soil carbon persistence by sheep grazing in a long-term calcareous grassland experiment
Encarnation, D.; Ashworth, D.; Bardgett, R.; Edwards, M.; Hambler, C.; Kristensen, J.; Hector, A.
10.1101/2024.09.11.611980 — ecology — Posted on 2024-09-14
3272 How does co-occurrence of Daphnia species affect their gut microbiome?
Houwenhuyse, S.; Massol, F.; Macke, E.; De Meester, L.; Vanoverberghe, I.; Stoks, R.; Decaestecker, E.
10.1101/2024.09.10.612237 — ecology — Posted on 2024-09-14
3274 Synergistic cross-kingdom host cell damage between Candida albicans and Enterococcus faecalis
Kapitan, M.; Niemiec, M. J.; Millet, N.; Brandt, P.; Chowdhury, M. E. K.; Czapka, A.; Abdissa, K.; Hoffmann, F.; Lange, A.; Veleba, M.; Nietzsche, S.; Mosig, A. S.; Loffler, B.; Marquet, M.; Makarewicz, O.; Kline, K. A.; Vylkova, S.; Swidergall, M.; Jacobsen, I. D.
10.1101/2024.09.11.612452 — microbiology — Posted on 2024-09-14
3275 Lack of cortistatin worsens neurological outcome and exacerbates aging-related glial and vascular dysfunction in stroke
Castillo Gonzalez, J.; Vargas Rodriguez, P.; Serrano Martinez, I.; Forte-Lago, I.; Price, M.; Buscemi, L.; Hirt, L.; Gonzalez-Rey, E.
10.1101/2024.09.11.611691 — immunology — Posted on 2024-09-14
3276 Effect of Alcohol and Cocaine Abuse on Neuronal and Non-Neuronal Cell Turnover in the Adult Human Hippocampus
Alkass, K.; Steiner, E.; Bernard, S.; Le Maitre, T. W.; Dhanabalan, G.; Landen, M.; Spalding, K.; Frisen, J.; Mash, D. C.; Druid, H.
10.1101/2024.09.10.612190 — neuroscience — Posted on 2024-09-14
3279 The myokine FGF21 associates with enhanced survival in ALS and mitigates stress-induced cytotoxicity
Guha, A.; Si, Y.; Smith, R.; Kazamel, M.; Jiang, N.; Smith, K. A.; Thalacker-Mercer, A.; Singh, B. K.; Ho, R.; Anadrabi, S.; Pereira, J. D. T. D. S.; Salgado, J. S.; Agrawal, M.; Velic, E. H.; King, P. H.
10.1101/2024.09.11.611693 — neuroscience — Posted on 2024-09-14
3283 Convpaint - Universal framework for interactive pixel classification using pretrained neural networks
Hinderling, L.; Witz, G.; Schwob, R.; Stojiljkovic, A.; Dobrzynski, M.; Vladymyrov, M.; Frei, J.; Graedel, B.; Frismantiene, A.; Pertz, O.
10.1101/2024.09.12.610926 — bioinformatics — Posted on 2024-09-14
3285 A benchmarking study of copy number variation inference methods using single-cell RNA-sequencing data
Chen, X.; Fang, L. T.; Chen, Z.; Chen, W.; Zhu, B.; Wu, H.; Moos, M.; Farmer, A.; Zeng, F.; Song, L.; Zhang, X.; Xiong, W.; Gong, S.; Jones, W.; Mason, C.; Wu, S.; Xiao, C.; Wang, C.
10.1101/2024.09.09.612120 — bioinformatics — Posted on 2024-09-14
3286 Impact of anatomic variability and other vascular factors on lamina cribrosa hypoxia
Lu, Y.; Hua, Y.; Lee, P.-Y.; Theophanous, A.; Tahir, S.; Tian, Q.; Sigal, I. A.
10.1101/2024.09.12.610282 — bioengineering — Posted on 2024-09-14
3287 A new Polerovirus species in plants from the Asparagaceae family defined by its RNA-silencing repressor protein P0
Dekker, R. J.; de Leeuw, W. C.; van Olst, M.; Ensink, W. A.; van Leeuwen, S.; Breit, T. M.; Jonker, M. J.
10.1101/2024.09.10.608920 — genomics — Posted on 2024-09-13
3288 Bone adhered soil as a source of target and environmental DNA and proteins
de Dios Martinez, T.; Bonucci, B.; Barbieri, R.; Kushniarevich, A.; D'Atanasio, E.; Dittmar, J. M.; Cessford, C.; Solnik, A.; Robb, J. E.; Warinner, C.; Oras, E.; Scheib, C. L.
10.1101/2024.09.10.611648 — genomics — Posted on 2024-09-14
3292 Vaginal Tissue Engineering via Gelatin-Elastin Fiber-Reinforced Hydrogels
Zambuto, S. G.; Kolluru, S.; Hamdaoui, A.; Mascot, A.; Sutcliffe, S.; Lowder, J.; Oyen, M. L.
10.1101/2024.09.09.611932 — bioengineering — Posted on 2024-09-13
3295 53BP1 deficiency leads to hyperrecombination using break-induced replication (BIR)
Shah, S. B.; Li, Y.; Li, S.; Hu, Q.; Wu, T.; Shi, Y.; Nguyen, T.; Ive, I.; Shi, L.; Wang, H.; Wu, X.
10.1101/2024.09.11.612483 — molecular biology — Posted on 2024-09-13
3296 Structural mimicry of UM171 and neomorphic cancer mutants co-opts E3 ligase KBTBD4 for HDAC1/2 recruitment
Chen, Z.; Chi, G.; Balo, T.; Chen, X.; Montes, B.; Clifford, S. C.; Szabo, T.; Kiss, A.; Herner, A.; Kotschy, A.; Bullock, A. N.
10.1101/2024.09.12.612738 — molecular biology — Posted on 2024-09-13
3297 Introduction of cytosine-5 DNA methylation sensitizes cells to oxidative damage
Krwawicz, J.; Sheeba, C. J.; Hains, K.; McMahon, T.; Zhang, Y.; Kriaucionis, S.; Sarkies, P.
10.1101/2024.09.13.612259 — molecular biology — Posted on 2024-09-13
3303 Wild type domestication: loss of intrinsic metabolic traits concealed by culture in rich media
Vezina, B.; Cooper, H. B.; Wisniewski, J. A.; Parker, M. H.; Jenney, A. W. J.; Holt, K. E.; Wyres, K. L.
10.1101/2024.09.12.612796 — microbiology — Posted on 2024-09-13
3305 Computational metabolic modeling unveils gut microbiomes role in metabolic shifts during murine cancer cachexia
Moissl-Eichinger, C.; Kuehnast, T.; Pototschnig, I.; Traeger, M.; Diener, C.; Habisch, H.; Vogel, A.; Wink, L.; Mahnert, A.; Madl, T.; Weichhart, T.; Schweiger, M.
10.1101/2024.09.13.612865 — microbiology — Posted on 2024-09-13
3310 Cognitive-and lifestyle-related microstructural variation in the ageing human hippocampus
Agyekum, T.; Garcia, C. L.; Fay, F.; Parent, O.; Bussy, A.; Devenyi, G. A.; Chakravarty, M. M.
10.1101/2024.09.09.612084 — neuroscience — Posted on 2024-09-13
3311 Probing other's Presence: Probabilistic Inference Across Brain Scales Reveals Enhanced Excitatory Synaptic Efficacy
Esmaeili, A.; Demolliens, M.; Viersen, M.; Ziaeemehr, A.; Isbaine, F.; Huguet, P.; Zaal, F.; Jirsa, V.; Boussaoud, D.; Hashemi, M.
10.1101/2024.09.09.612006 — neuroscience — Posted on 2024-09-13
3314 iSeqsSearch: Incremental Protein Search for iBlast/iMMSeqs2/iDiamond
Yoo, H.; Refahi, M. S.; Polikar, R.; Sokhansanj, B. A.; Brown, J. R.; Rosen, G. L.
10.1101/2024.09.09.612094 — bioinformatics — Posted on 2024-09-13
3315 Informing biologically relevant signal from spatial transcriptomic data
Radkevich, E.; D'Souza, D.; Mattiuz, R.; Merand, R.; Chen, R.; Morgenroth-Rebin, J.; Angeliadis, K.; Nelson, D.; Kara, A.; Dawson, T.; De Souza, I.; Nie, K.; Hamon, P.; Hegde, S.; Boumelha, J.; Brody, R.; Ozbey, S.; Hennequin, C.; Feng, D.; Dai, J.; Gonzalez-Kozlova, E.; Chen, Z.; Kim-Schulze, S.; Gnjatic, S.; Merad, M.; Roudko, V.
10.1101/2024.09.09.610361 — bioinformatics — Posted on 2024-09-13
3316 Magnetic Resonance Imaging of Gastric Motility in Conscious Rats
Wang, X.; Alkaabi, F.; Cornett, A.; Choi, M.; Scheven, U. M.; Di Natale, M. R.; Furness, J. B.; Liu, Z.
10.1101/2024.09.09.612090 — bioengineering — Posted on 2024-09-13
3318 Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
Gloegl, M.; Krishnakumar, A.; Ragotte, R.; Goreshnik, I.; Coventry, B.; Bera, A. K.; Kang, A.; Joyce, E.; Ahn, G.; Huang, B.; Yang, W.; Chen, W.; Sanchez, M. G.; Koepnick, B.; Baker, D.
10.1101/2024.09.13.612773 — biochemistry — Posted on 2024-09-13
3319 Direct measurement of PIP2 densities in biological membranes using a peptide-based sensor
Menon, V. K.; Wu, J.; Alonzo, A.; Rogers, K.; Scrudders, K. L.; Selvarajan, S.; Walke, A.; Kundu, R.; Datta, A.; Low-Nam, S. T.
10.1101/2024.09.11.612554 — biochemistry — Posted on 2024-09-13
3321 The mitochondrial dicarboxylate carrier mediates in vivo hepatic gluconeogenesis
Pape, D. J.; Falls-Hubert, K. C.; Merrill, R. A.; Ahmed, A.; Qian, Q.; McGivney, G. R.; Sobieralski, P.; Rauckhorst, A. J.; Yang, L.; Taylor, E. B.
10.1101/2024.09.12.612761 — biochemistry — Posted on 2024-09-13
3322 Epigenomic, transcriptomic and proteomic characterizations of reference samples
Nepal, C.; Chen, W.; Chen, Z.; Wroble, J. A.; Xie, L.; Liao, W.; Xiao, C.; Farmer, A.; Moos, M.; Jones, W.; Chen, X.; Wang, C.
10.1101/2024.09.09.612110 — genomics — Posted on 2024-09-13
3323 PROS1 released by human lung basal cells upon SARS-CoV-2 infection facilitates epithelial cell repair and limits inflammation.
Simakou, T.; Szemiel, A. M.; MacDonald, L.; Kerr, K.; Frew, J.; Doohan, M.; Diallo, K.; Somma, D.; Hardy, O. M.; Elmesmari, A.; McSharry, C.; Otto, T. D.; Patel, A. H.; Kurowska-Stolarska, M.
10.1101/2024.09.11.612489 — cell biology — Posted on 2024-09-13
3324 Development of a DNA-encoded library screening method DEL Zipper to empower the study of RNA-targeted chemical matter
Ma, Z.; Zou, B.; Zhao, J.; Zhang, R.; Zhu, Q.; Wang, X.; Xu, L.; Gao, X.; Hu, X.; Feng, W.; Luo, W.; Wang, M.; He, Y.; Yu, Z.; Cui, W.; Zhang, Q.; Kuai, L.; Su, W.
10.1101/2024.09.13.612806 — molecular biology — Posted on 2024-09-13
3326 Intranasal parainfluenza virus-vectored vaccine expressing SARS-CoV-2 spike protein of Delta or Omicron B.1.1.529 induces mucosal and systemic immunity and protects hamsters against homologous and heterologous challenge
Park, H.-S.; Matsuoka, Y.; Santos, C.; Luongo, C.; Liu, X.; Yang, L.; Kaiser, J. A.; Duncan, E. F.; Johnson, R. F.; Teng, I.-T.; Kwong, P. D.; Buchholz, U. J.; Le Nouën, C.
10.1101/2024.09.12.612598 — microbiology — Posted on 2024-09-13
3328 LolA and LolB are conserved in Bacteroidetes and are crucial for gliding motility and Type IX secretion.
De Smet, T.; Baland, E.; Giovannercole, F.; Mignon, J.; Lizen, L.; Dugauquier, R.; Lauber, F.; Dieu, M.; Lima-Mendez, G.; Michaux, C.; Devos, D.; Renzi, F.
10.1101/2024.09.13.612696 — microbiology — Posted on 2024-09-13
3329 Lactobacillus crispatus S-layer proteins modulate innate immune response and inflammation in the lower female reproductive tract.
Decout, A.; Krasias, I.; Roberts, L.; Gimeno Molina, B.; Charenton, C.; Brown Romero, D.; Tee, Q. Y.; Marchesi, J. R.; Ng, S.; Sykes, L.; Bennett, P. R.; MacIntyre, D. A.
10.1101/2024.09.13.612838 — microbiology — Posted on 2024-09-13
3331 The role of PilU in the surface behaviors of Pseudomonas aeruginosa
Zhang, J.; Luo, Y.; Zong, Y.; Lu, S.; Shi, Y.; Jin, F.; Zhao, K.
10.1101/2024.09.12.612798 — microbiology — Posted on 2024-09-13
3332 Phage-phage competition and biofilms reduce the efficacy of a combination of two virulent bacteriophages against Pseudomonas aeruginosa
Buerkle, M.; Korf, I. H. E.; Lippegaus, A.; Krautwurst, S.; Rohde, C.; Weissfuss, C.; Nouailles, G.; Menatong Tene, X.; Gaborieau, B.; Ghigo, J.-M.; Ricard, J.-D.; Hocke, A. C.; Papenfort, K.; Debarbieux, L.; Witzenrath, M.; Wienhold, S.-M.; Krishnamoorthy, G.
10.1101/2024.09.13.612609 — microbiology — Posted on 2024-09-13
3333 Identification of a fungal antibacterial endopeptidase that modulates immune responses
Machata, S.; Bertsche, U.; Hoffmann, F.; Fattal, Z. M.; Kage, F.; Flak, M.; Iliou, A. N. J.; Hillmann, F.; von Eggeling, F.; Slevogt, H.; Brakhage, A. A.; Jacobsen, I. D.
10.1101/2024.09.13.612890 — microbiology — Posted on 2024-09-13
3334 Bacterial genome encoded ParMs
Ali, S.; Koh, A.; Popp, D.; Tanaka, K.; Kitaoku, Y.; Miyazaki, N.; Iwasaki, K.; Mitsuoka, K.; Robinson, R. C.; Narita, A.
10.1101/2024.09.12.612785 — microbiology — Posted on 2024-09-13
3335 Differential Immunoregulation by Human Surfactant Protein A Variants Determines Severity of SARS-CoV-2-induced Lung Disease
Jacob, I. B.; Lawal, A. O.; Mahmoud, S. S.; Kopsack, E. M.; Reynolds, E. S.; Meng, Q.; Fan, H.; Massa, P. T.; Thangamani, S.; Jia, H.; Wang, G.
10.1101/2024.09.11.612497 — immunology — Posted on 2024-09-13
3337 Chronobiological rhythms control of site- and cell-specific miRNA and mRNA genes and networks across the central nervous system
Zacharias, A. M.; O'Connor, C. D.; Topouza, D. G.; Fang, Z. Y.; Ghazinejad, H.; Chen, H.; Duan, Q.; Ghasemlou, N.
10.1101/2024.09.09.612109 — neuroscience — Posted on 2024-09-13
3339 Structure - silencing duration relationships in RNAi medicines in rapidly dividing cells
Kremer, A.; Ryaykenen, T.; Segarra-Visent, X.; Sauer, M.; Tang, Q.; Cooper, D. A.; Echeverria, D.; Philouze, C.; Bayon, E.; Georgess, D.; Haraszti, R. A.
10.1101/2024.09.09.612002 — pharmacology and toxicology — Posted on 2024-09-13
3347 Advanced Tissue Technologies of Blood-Brain Barrier Organoids as High Throughput Toxicity Readouts in Drug Development
Bell, L.; Simonneau, C.; Zanini, C.; Kassianidou, E.; Zundel, C.; Neff, R.; Steinhuber, B.; Tecilla, M.; Odermatt, A.; Villasenor, R.; Stokar-Regenscheit, N.
10.1101/2024.09.09.611987 — pathology — Posted on 2024-09-13
3348 Towards genuine three-dimensional diffusion imaging with physiological motion compensation
Wang, Y.; Weng, D.; Zhang, J.; Qian, T.; Liu, W.; Zhou, K.; Wu, Y.; Zhang, B.; Li, Q.; Jing, J.; Zhang, Z.
10.1101/2024.09.08.611927 — bioengineering — Posted on 2024-09-13
3349 eDNA sampling systems for salmon ecosystem monitoring
Deeg, C. M.; Saunders, R. G.; Tam, C.; Kaukinen, K.; Li, S.; Bass, A. L.; Uu-a-thluk Fisheries, ; Miller, K. M.
10.1101/2024.09.11.610878 — genomics — Posted on 2024-09-13
3352 Targets of influenza Human T cell response are mostly conserved in H5N1
Sidney, J.; Kim, A.; de Vries, R. D.; Peters, B.; Meade, P. S.; Krammer, F.; Grifoni, A.; Sette, A.
10.1101/2024.09.09.612060 — immunology — Posted on 2024-09-13
3353 Survey of gene, lncRNA and transposon transcription patterns in four mouse organs highlights shared and organ-specific sex-biased regulation
Zhuang, Q. K.-W.; Bauermeister, K.; Galvez Lopez, J. H.; AlOgayil, N.; Batdorj, E.; Pardo-Manuel de Villena, F.; Taketo, T.; Bourque, G.; Naumova, A. K.
10.1101/2024.09.10.612032 — genomics — Posted on 2024-09-13
3354 START domains generate paralog-specific regulons from a single network architecture
Holub, A. S.; Choudury, S. G.; Andrianova, E. P. Y.; Dresden, C. E.; Urquidi Camacho, R.; Jouline, I.; Husbands, A. Y.
10.1101/2024.09.09.612080 — genomics — Posted on 2024-09-13
3359 A scalable approach to absolute quantitation in metabolomics
Ferro, L. S.; Wong, A. Y. L.; Howland, J.; Costa, A. S. H.; Pruyne, J. G.; Shah, D.; Lauterbach, J. D.; Hooper, S. B.; Delmar, M. C.; Geremia, J.; Kassis, T.; Kanarek, N.; Campbell, J. M.
10.1101/2024.09.09.609906 — systems biology — Posted on 2024-09-13
3360 ElixirSeeker: A Machine Learning Framework Utilizing Attention-Driven Fusion of Molecular Fingerprints for the Discovery of Anti-Aging Compounds
Pan, Y.; Cai, H.; Ye, F.; Xu, W.; Huang, Z.; Zhu, J.; Gong, Y.; Li, Y.; Ezemaduka, A. N.; Gao, S.; Liu, S.; Li, G.; Li, H.; Yang, J.; Ning, J.; Xian, B.
10.1101/2024.09.08.611839 — systems biology — Posted on 2024-09-13
3361 Differentiating wild and domesticated enset (Musaceae) using phytolith analysis
Castillo Cobo, C.; Beldados, A.; Ryan, P.; Bond, S.; Vrydaghs, L.; Lulekal Molla, E.; Borrell, J.; Hunt, H.; Fuller, D. Q.
10.1101/2024.09.09.611979 — plant biology — Posted on 2024-09-13
3369 Demographic responses to climatic changes during the Final Palaeolithic in Europe
Schmidt, I.; Gehlen, B.; Winkler, K.; Arrizabalaga, A.; Arts, N.; Bicho, N.; Crombe, P.; Eriksen, B. V.; Grimm, S. B.; Kapustka, K.; Langlais, M.; Mevel, L.; Naudinot, N.; Nerudova, Z.; Niekus, M.; Peresani, M.; Riede, F.; Sauer, F.; Schön, W.; Sobkowiak-Tabaka, I.; Vandendriessche, H.; Weber, M.-J.; Zander, A.; Zimmermann, A.; Maier, A.
10.1101/2024.09.11.612499 — ecology — Posted on 2024-09-13
3370 The resilience of the oral microbiome and lability of the hair microbiome across host environments in wild and captive lemurs
Burten, R. B.; Lawler, R. R.; Ratsirarson, J.; Ranaivonasy, J.; Leduc, R. C.; Bhagat, A.; Lopez, A.; Kamilar, J. M.
10.1101/2024.09.09.612164 — ecology — Posted on 2024-09-13
3372 Detecting microbial engraftment after FMT: sorting signals from noise using placebo sequencing and culture-enriched metagenomics
Shekarriz, S.; Szamosi, J. C.; Whelan, F. J.; Lau, J. T.; Libertucci, J.; Rossi, L.; Shah, M.; Wolfe, M.; Lee, C. H.; Moayyedi, P.; Surette, M. G.
10.1101/2024.09.11.612315 — microbiology — Posted on 2024-09-13
3373 IL-34 empowers regulatory T cells with novel non-canonical function to safeguard brain barrier integrity during neuro-inflammation.
Van Hoecke, L.; Verreycken, J.; Van Acker, L.; Amelinck, L.; Xie, J.; Castelein, J.; Van Wonterghem, E.; Van Imschoot, G.; Burgelman, M.; Vanherle, S.; Dewachter, I.; Baeten, P.; Broux, B.; Vandenbroucke, R. E.
10.1101/2024.09.09.611994 — immunology — Posted on 2024-09-13
3374 Preventing surgery induced immune suppression and metastases by inhibiting PI3K-gamma signalling in Myeloid-Derived Suppressor Cells.
Angka, L.; Tennakoon, G.; Cook, D. P.; Martel, A. B.; Market, M. R.; Tanese de Souza, C.; Cummins, E.; Samudio, I.; Kekre, N.; Ardolino, M.; Vanderhyden, B.; Kennedy, M. A.; Auer, R. C.
10.1101/2024.09.08.611916 — immunology — Posted on 2024-09-13
3377 CLIMATE BRAIN - Questionnaires, Tasks and the Neuroimaging Dataset
Zaremba, D. A.; Kossowski, B.; Wypych, M.; Jednorog, K.; Michalowski, J. M.; Klockner, C. A.; Wierzba, M.; Marchewka, A.
10.1101/2024.09.12.612592 — neuroscience — Posted on 2024-09-13
3378 Revisiting the cytogenetics of Vellozia Vand.: immunolocalization of KLN1 elucidates the chromosome number for the genus
Braz, G. T.; Riboldi, L. B.; Pinto, M. S.; Forni-Martins, E. R.; Yassitepe, J. E. C. T.; Dante, R. A.; Gerhardt, I. R.
10.1101/2024.09.10.612026 — plant biology — Posted on 2024-09-13
3382 A genome-wide association screen for genes affecting leaf trichome development and epidermal metal accumulation in Arabidopsis
Bezvoda, R.; Landeo-Rios, Y. M.; Kubatova, Z.; Kollarova, E.; Kulich, I.; Busch, W.; Zarsky, V.; Cvrckova, F.
10.1101/2024.09.10.612273 — plant biology — Posted on 2024-09-13
3383 NRF2 translation block by inhibition of cap-dependent initiation sensitizes lymphoma cells to ferroptosis and CAR-T immunotherapy
Manara, P.; Newsam, A. D.; Saralamma, V. V.; Russo, M. V.; Martinez, A. B.; Fattakhov, N.; Cunningham, T. A.; Alaoui, A. Y.; Chahar, D.; Carbone, A. M.; Lightfuss, O. B.; Barroso, A. M.; Hoffman, K. S.; Maura, F.; Bilbao, D.; Schatz, J. H.
10.1101/2024.09.09.612133 — cancer biology — Posted on 2024-09-13
3387 Strong Selection, but low repeatability: Temperature-specific effects on genomic predictions of adaptation
Rego, A.; Baur, J.; Girard-Tercieux, C.; de la Paz Celorio-Mancera, M.; Stelkens, R.; Berger, D.
10.1101/2024.09.12.612579 — evolutionary biology — Posted on 2024-09-13
3392 IFT and BBSome proteins are required for Leishmania mexicana pathogenicity, but flagellar motility is dispensable
Beneke, T.; Neish, R.; Catta-Preta, C. M. C.; Smith, J.; Valli, J.; McCoy, C. J.; Albuquerque-Wendt, A.; Mottram, J. C.; Gluenz, E.
10.1101/2024.09.13.612850 — cell biology — Posted on 2024-09-13
3393 Unlocking hidden phage diversity to complete the BASEL collection for systematic exploration of phage-host interactions
Humolli, D.; Maffei, E.; Heyer, Y.; Agustoni, E.; Piel, D.; Shaidullina, A.; Willi, L.; Sauer, P.; Estermann, F.; Cuenod, A.; Buser, D. P.; Egli, A.; Hiller, S.; Dunne, M.; Harms, A.
10.1101/2024.09.12.612763 — microbiology — Posted on 2024-09-13
3395 IL-1b-mediated Immunometabolic Adaptation in Corneal Epithelial Cells
Sanches, J. M.; Ramachandran, R. A.; Mussi, N.; Baniasadi, H.; Robertson, D. M.
10.1101/2024.09.08.611874 — immunology — Posted on 2024-09-13
3399 Population coding of auditory space in the dorsal inferior colliculus persists with altered binaural cues
Rogalla, M. M.; Quass, G. L.; Yardley, H.; Martinez-Voigt, C.; Ford, A. N.; Wallace, G.; Dileepkumar, D.; Corfas, G.; Apostolides, P. F.
10.1101/2024.09.13.612867 — neuroscience — Posted on 2024-09-13
3403 Trace Elements in Fish: Assessment of bioaccumulation and associated health risks.
Naz, S.; Ullah, Q.; Fouad, D.; Qadeer, A.; Lateef, M.; Hassan, M. W.; Chatha, A. M. M.
10.1101/2024.09.08.611911 — zoology — Posted on 2024-09-13
3404 Leveraging large language models for metabolic engineering design
Li, X.; Liang, Z.; Guo, Z.; Liu, Z.; Wu, K.; Luo, J.; Zhang, Y.; Liu, L.; Sun, M.; Huang, Y.; Tang, H.; Chen, Y.; Yu, T.; Nielsen, J.; Li, F.
10.1101/2024.09.09.612023 — systems biology — Posted on 2024-09-13
3407 Aging-associated vacuolation of multi-ciliated cells in the distal mouse oviduct reflects unique cell identity and luminal microenvironment
Harwalkar, K.; Yamanaka, N.; Pacis, A. S.; Zhao, S.; Teng, K.; Pitman, W.; Taskar, M.; Lynn, V.; Thornton, A. F.; Ford, M. J.; Yamanaka, Y.
10.1101/2024.09.07.611808 — physiology — Posted on 2024-09-13
3409 DNA Damage Response Deficiency Enhances Neuroblastoma Progression and Sensitivity to Combination PARP and ATR Inhibition
Hayes, M. N.; Cohen-Gogo, S.; Kee, L.; Weiss, A.; Layeghifard, M.; Ladumor, Y.; Valencia-Sama, I.; Rajaselvam, A.; Kaplan, D. R.; Villani, A.; Shlien, A.; Morgenstern, D. R.; Irwin, M. S.
10.1101/2024.09.09.612065 — cancer biology — Posted on 2024-09-13
3410 Pyjacker identifies enhancer hijacking events in acute myeloid leukemia including MNX1 activation via deletion 7q
Sollier, E.; Riedel, A.; Toprak, U. H.; Wierzbinska, J. A.; Weichenhan, D.; Schmid, J. P.; Hakobyan, M.; Touzart, A.; Jahn, E.; Vick, B.; Brown-Burke, F.; Kelly, K.; Kelekci, S.; Pejkovska, A.; Goyal, A.; Baehr, M.; Breuer, K.; Chen, M.-J. M.; Llamazares-Prada, M.; Hartmann, M.; Schoenung, M.; Correia, N.; Trumpp, A.; Abdullah, Y.; Klingmueller, U.; Mughal, S. S.; Brors, B.; Westermann, F.; Schlesner, M.; Vosberg, S.; Herold, T.; Greif, P. A.; Pfeifer, D.; Luebbert, M.; Fischer, T.; Heidel, F.; Gebhard, C.; Walter, W.; Haferlach, T.; Eisfeld, A.-K.; Mrozek, K.; Nicolet, D.; Bullinger, L.; Smee
10.1101/2024.09.11.611224 — cancer biology — Posted on 2024-09-13
3414 Novae: a graph-based foundation model for spatial transcriptomics data
Blampey, Q.; Benkirane, H.; Bercovici, N.; Andre, F.; Cournede, P.-H.
10.1101/2024.09.09.612009 — bioinformatics — Posted on 2024-09-13
3415 Inkjet-printed graphene multielectrode arrays: an accessible platform for in vitro cardiac electrophysiology
Lumpuy-Castillo, J.; Fu, Y.; Avila, A.; Solodka, K.; Li, J.; Lorenzo, O.; Zeglio, E.; Garma, L. D.
10.1101/2024.09.09.611887 — bioengineering — Posted on 2024-09-13
3419 Predictive Prioritization of Enhancers Associated with Pancreas Disease Risk
Wang, L.; Baek, S.; Prasad, G.; Wildenthal, J.; Guo, K.; Sturgill, D.; Truongvo, T.; Char, E.; Pegoraro, G.; McKinnon, K.; The Pancreatic Cancer Cohort Consortium, ; The Pancreatic Cancer Case-Control Consortium, ; Hoskins, J. W.; Amundadottir, L. T.; Arda, E.
10.1101/2024.09.07.611794 — genomics — Posted on 2024-09-13
3420 Mind the polar sun: Solar radiations trigger frequent heat stress in breeding king penguins, despite relatively cool air temperatures.
Noiret, A.; Lewden, A.; Lemonnier, C.; Bocquet, C.; Montblanc, M.; Bertile, F.; Hoareau, M.; Marcon, E.; Robin, J.-P.; Viblanc, V. A.; Stier, A.
10.1101/2024.09.09.611977 — evolutionary biology — Posted on 2024-09-13
3423 High-parametric protein maps reveal the spatial organization in early-developing human lung
Sariyar, S.; Sountoulidis, A.; Hansen, J. N.; Salas, S. M.; Mardamshina, M.; Martinez Casals, A.; Ballllosera Navarro, F.; Andrusivova, Z.; Li, X.; Czarnewski, P.; Lundeberg, J.; Linnarsson, S.; Nilsson, M.; Sundstrom, E.; Samakovlis, C.; Lundberg, E.; Ayoglu, B.
10.1101/2024.01.25.577163 — developmental biology — Posted on 2024-09-13
3424 Non-canonical IL-22 receptor signaling remodels the mucosal barrier during fungal immunosurveillance
Millet, N.; Sekar, J.; Solis, N. V.; Millet, A.; Aggor, F. E. Y.; Wildeman, A.; Lionakis, M. S.; Gaffen, S. L.; Jendzjowsky, N.; Filler, S. G.; Swidergall, M.
10.1101/2024.09.08.611873 — immunology — Posted on 2024-09-13
3425 Modulatory Effects of M3 Muscarinic Acetylcholine Receptor on Inflammatory Profiles of Human Memory T Helper Cells
Gholizadeh, F.; Hajiaghayi, M.; Choi, J. S.; Little, S. R.; Rahbari, N.; Brotto, K.; Han, E.; Shih, S. C. C.; Darlington, P. J.
10.1101/2024.09.08.611875 — immunology — Posted on 2024-09-13
3427 Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer's disease through disrupted regulated intramembrane proteolysis
Ziff, O. J.; Jolly, S.; Casey, J. M.; Granat, L.; Samra, S.; Seto-Salvia, N.; Alatza, A.; Phadke, L.; Galet, B.; Ravassard, P.; Potier, M.-C.; Fox, N. C.; Hardy, J.; Salih, D.; Whiting, P.; Ducotterd, F.; Patani, R.; Wray, S.; Arber, C.
10.1101/2024.09.09.611621 — neuroscience — Posted on 2024-09-13
3430 Development of sensorimotor responses in larval zebrafish: a comparison between wild-type and GCaMP6s transgenic line
Caperaa, M.; Roland-Caveriviere, M.; Herdman, C.; Imloul, N.; Poulin, S.; Lemieux, M.; De Koninck, P.; Bosse, G. D.
10.1101/2024.09.10.612316 — neuroscience — Posted on 2024-09-13
3433 RoCi - A Single Step Multi-Copy Integration System Based on Rolling-Circle Replication
Antsotegi-Uskola, M.; D'Ambrosio, V.; Jarczynska, Z. D.; Vanegas, K. G.; Morera-Gomez, M.; Wang, X.; Larsen, T. O.; Mouillon, J.-M.; Mortensen, U. H.
10.1101/2024.09.13.612835 — synthetic biology — Posted on 2024-09-13
3435 Evolutionary acquisition of a primitive light-dependent nuclear relocation in Marchantia polymorpha
Iwabuchi, K.; Yagi, H.; Moriya, K. C.; Komatsu, A.; Suetsugu, N.; Sakai, Y.; Shimada, T.; Nishihama, R.; Kohchi, T.; Harada, A.; Watanabe, Y.-h.; Ueda, H.; Hara-Nishimura, I.
10.1101/2024.09.11.611950 — plant biology — Posted on 2024-09-13
3436 Merkel cell carcinoma-derived macrophage migration inhibitory factor (MIF) may promote persistence of Chronic Lymphocytic Leukemia
Alencar, G. F.; Rodriguez, H. J.; Pulliam, T. H.; Remington, A. S.; Gilmour, M. W.; Alam, R.; Jabbour, A. J.; Mullen, L. J.; DeBuysscher, B. L.; Nghiem, P.; Taylor, J. J.
10.1101/2024.09.09.611517 — cancer biology — Posted on 2024-09-13
3437 Mitochondrial metabolism is a key determinant of chemotherapy sensitivity in Colorectal Cancer
Moss, D. Y.; Brown, C.; Shaw, A.; McCann, C.; Lewis, N.; Phillips, A.; Gallagher, S.; McDaid, W. J.; Roe, A.; Coughlan, A. Y.; Cavanagh, B.; Ormsby, C.; Falcone, F.; McCole, R.; Monteith, S.; Rogan, E.; Downs, M.; Malla, S. B.; Emerson, A. J.; Mohammed-Smith, L.; Sharkey, S.; Gallagher, P. F.; Banerjee, A.; Pandor, S.; Greer, B.; Elliott, C.; Ryan, A.; Dunne, P. D.; Coyle, V.; Mills, I. G.; McDade, S. S.; Sansom, O.; Ni Chonghaile, T.; Longley, D. B.; LaBonte, M. J.; Kerr, E. M.
10.1101/2024.09.12.611189 — cancer biology — Posted on 2024-09-13
3438 An integrated stress response-independent role of GCN2 prevents excessive ribosome biogenesis and mRNA translation
Roman-Trufero, M.; Kleijn, I. T.; Blighe, K.; Zhou, J.; Saavedra-Garcia, P.; Gaffar, A.; Christoforou, M.; Bellotti, A.; Abrahams, J.; Atrih, A.; Lamont, D. J.; Gierlinski, M.; Jayaprakash, P.; Michel, A. M.; Aboagye, E.; Yuneva, M.; Masson, G. R.; Shahrezaei, V.; Auner, H. W.
10.1101/2024.09.10.611650 — cancer biology — Posted on 2024-09-13
3439 Sequential ATR and PARP Inhibition Overcomes Acquired DNA Damaging Agent Resistance in Pancreatic Ductal Adenocarcinoma
Herbert, K. J.; Upstill-Goddard, R.; Dreyer, S. B.; Rebus, S.; Australian Pancreatic Cancer Genome Initiative, ; Pilarsky, C.; Mukhopadhyay, D.; Lord, C. J.; Genomics Innovation Alliance, ; Biankin, A. V.; Froeling, F. E. M.; Chang, D. K.
10.1101/2024.09.09.609499 — cancer biology — Posted on 2024-09-13
3440 Aberrant activation of wound healing programs within the metastatic niche facilitates lung colonization by osteosarcoma cells
Reinecke, J. B.; Jimenez Garcia, L.; Gross, A. C.; Cam, M.; Cannon, M. V.; Gust, M. J.; Sheridan, J. P.; Gryder, B. E.; Dries, R.; Roberts, R. D.
10.1101/2024.01.10.575008 — cancer biology — Posted on 2024-09-13
3441 Active repression of cell fate plasticity by PROX1 safeguards hepatocyte identity and prevents liver tumourigenesis
Lim, B.; Kamal, A.; Gomez Ramos, B.; Adrian Segarra, J.; Ibarra, I.; Dignas, L.; Kindinger, T.; Volz, K.; Rahbari, M.; Rahbari, N.; Poisel, E.; Kafetzopoulou, K.; Bose, L.; Breinig, M.; Heide, D.; Gallage, S.; Barragan Avila, J.; Wiethoff, H.; Berest, I.; Schnabellehner, S.; Schneider, M.; Becker, J.; Helm, D.; Grimm, D.; Makinen, T.; Tschaharganeh, D.; Heikenwalder, M.; Zaugg, J. B.; Mall, M.
10.1101/2024.09.10.612045 — cancer biology — Posted on 2024-09-13
3442 Leukemia-derived apelin selects endothelial niche clones to promote tumorigenesis
Baron, C. S.; Mitchell, O.; Avagyan, S.; Menard, R.; Yang, S.; Robertson, A. L.; Potluri, R.; Shendure, J.; Madelaine, R.; McKenna, A.; Zon, L. I.
10.1101/2024.09.09.612077 — cancer biology — Posted on 2024-09-13
3444 Inferring cell differentiation maps from lineage tracing data
Sashittal, P.; Zhang, R.; Law, B.; Strzalkowski, A.; Schmidt, H.; Bolondi, A.; Chan, M.; Raphael, B.
10.1101/2024.09.09.611835 — bioinformatics — Posted on 2024-09-13
3445 niiv: Fast Self-supervised Neural ImplicitIsotropic Volume Reconstruction
Troidl, J.; Liang, Y.; Beyer, J.; Tavakoli, M.; Danzl, J. G.; Hadwiger, M.; Pfister, H.; Tompkin, J.
10.1101/2024.09.07.611785 — bioinformatics — Posted on 2024-09-13
3447 CNValidatron, automated validation of CNV calls using computer vision
Montalbano, S.; Ingason, A.; Werge, T.; Gaadin, J.; Stefansson, H.; Walters, B.; Jonsson, G.; Stefansson, K.
10.1101/2024.09.09.612035 — bioinformatics — Posted on 2024-09-13
3448 EmbSAM: Cell boundary localization and Segment Anything Model for fast images of developing embryos
Zhao, C.; Li, Z.; Zhang, P.; Chen, Y.; Ye, P.; Wong, M.-K.; Chan, L.-Y.; Yan, H.; Tang, C.; Guan, G.; Zhao, Z.
10.1101/2024.09.07.611795 — bioinformatics — Posted on 2024-09-13
3449 Three-color single-molecule localization microscopy in chromatin
Acosta, N.; Gong, R.; Su, Y.; Frederick, J.; Medina, K.; Li, W. S.; Mohammadian, K.; Almassalha, L.; Backman, V.
10.1101/2024.09.09.612161 — bioengineering — Posted on 2024-09-13
3450 Expansion of functional human salivary acinar cell spheroids with reversible thermo-ionically crosslinked 3D hydrogels
Munguia-Lopez, J. G.; Pillai, S.; Zhang, Y.; Gantz, A.; Camasao, D. B.; Nazhat, S. N.; Kinsella, J. M.; Tran, S. D.
10.1101/2024.09.09.612117 — bioengineering — Posted on 2024-09-13
3451 A computationally guided approach to improve expression of VHH binders
OZDEMIR, E. S.; Tolley, J.; Goncalves, F.; Gomes, M.; Wagnell, E.; Branchaud, B.; Ranganathan, S.
10.1101/2024.09.07.611840 — bioengineering — Posted on 2024-09-13
3457 Epigenetic regulation of global proteostasis dynamics by RBBP5 ensures mammalian organismal health
Kubra, S.; Sun, M.; Dion, W.; Catak, A.; Luong, H.; Wang, H.; Pan, Y.; Liu, J.-J.; Ponna, A.; Sipula, I.; Jurczak, M. J.; Liu, S.; Zhu, B.
10.1101/2024.09.13.612812 — cell biology — Posted on 2024-09-13
3458 Discovery of novel quinoline papain-like protease inhibitors for COVID-19 through topology constrained molecular generative model
Shang, J.; Ran, T.; Lu, Y.; Yang, Q.; Zhang, G.; Zhou, P.; Li, W.; Xu, M.; Tang, J.; Dai, M.; Zhong, J.; Chen, H.; He, P.; Zhou, A.; Xue, B.; Chen, J.; Zhang, J.; Wu, K.; Wu, X.; Tang, M.; Chen, X.; Chen, H.
10.1101/2024.09.07.611841 — microbiology — Posted on 2024-09-13
3459 Sympathetic innervation of interscapular brown adipose tissue is not a predominant mediator of OT-elicited reductions of body weight gain and adiposity in male diet-induced obese rats
Edwards, M. M.; Nguyen, H. K.; Dodson, A. D.; Herbertson, A. J.; Honeycutt, M. K.; Slattery, J. D.; Rambousek, J. R.; Tsui, E.; Wolden-Hanson, T.; Wietecha, T. A.; Graham, J. L.; Tapia, G. P.; Sikkema, C. L.; O'Brien, K. D.; Mundinger, T. O.; Peskind, E. R.; Ryu, V.; Havel, P. J.; Khan, A. M.; Tabosky, G. J.; Blevins, J. E.
10.1101/2024.09.12.612710 — neuroscience — Posted on 2024-09-13
3460 Development of a Marmoset Apparatus for Automated Pulling (MarmoAAP) to Study Cooperative Behaviors
Meisner, O. C.; Shi, W.; Fagan, N. A.; Greenwood, J.; Jadi, M.; Nandy, A. S.; Chang, S. W. C.
10.1101/2024.02.16.579531 — neuroscience — Posted on 2024-09-13
3461 Controlled retrieval relies on directed interactions between semantic control regions and visual cortex: MEG evidence from oscillatory dynamics
Eisenhauer, S.; Zhang, M.; Krieger-Redwood, K.; Aveyard, R.; Jackson, R. L.; Cornelissen, P. L.; Smallwood, J.; Jefferies, E.
10.1101/2024.09.07.611827 — neuroscience — Posted on 2024-09-13
3462 Integrated multi-model analysis of intestinal inflammation exposes key molecular features of preclinical and clinical IBD
Gonzalez Acera, M.; Patankar, J. V.; Erkert, L.; Cineus, R.; Gamez Belmonte, R.; Leupold, T.; Bubeck, M.; Bao, L.-l.; Dinkel, M.; Wang, R.; Limberger, H.; Stolzer, I.; Gerlach, K.; Mascia, F.; Koop, K.; Plattner, C.; Sturm, G.; Weigmann, B.; Guenther, C.; Wirtz, S.; Hildner, K.; Kuehl, A. A.; Siegmund, B.; Atreya, R.; The IBDome Consortium, ; Hegazy, A. N.; Trajanoski, Z.; Neurath, M. F.; Becker, C.
10.1101/2024.08.14.607902 — systems biology — Posted on 2024-09-13
3468 Nuclear basket proteins regulate the distribution and mobility of nuclear pore complexes in budding yeast
Zsok, J.; Simon, F.; Bayrak, G.; Isaki, L.; Kerff, N.; Kicheva, Y.; Wolstenholme, A.; Weiss, L. E.; Dultz, E.
10.1101/2023.09.28.558499 — cell biology — Posted on 2024-09-13
3469 IL-6 and IL-27 negatively regulate CRTAM-expressing CD4+ T-cells associated with lymphoid-driven synovitis.
Derrac Soria, A.; Lewis, M. J.; Liu, X.; Twohig, J. P.; Monaco, F.; Dimonte, S.; Cardus Figueras, A.; Morrin, A.; Guy, C.; Cossins, B. C.; Benson, R.; Andrews, R.; Choy, E. H.; Garside, P.; Huwaikem, M.; Stemmler, M. P.; Brabletz, S.; Brabletz, T.; Siebzehnrubl, F. A.; Rodrigues, N.; Jenkins, B. J.; Pitzalis, C.; Jones, G. W.; Jones, S. A.
10.1101/2024.09.03.610972 — immunology — Posted on 2024-09-13
3470 Microbial metabolite-guided CAR T cell engineering enhances anti-tumor immunity via epigenetic-metabolic crosstalk
Staudt, S.; Nikolka, F.; Perl, M.; Franz, J.; Leblay, N.; Yuan, X.-K.; Warmuth, L.; Fantes, M. A.; Skorpskaite, A.; Fei, T.; Bromberg, M.; San Martin-Uriz, P.; Rodriguez-Madoz, J. R.; Ziegler-Martin, K.; Adil-Gholam, N.; Benz, P.; Tran Huu, P.; Stein-Thoeringer, C.; Schmitt, M.; Kleigrewe, K.; Freitag, F.; Riester, Z.; Weber, J.; Mangold, K.; Einsele, H.; Prosper, F.; Ellmeier, W.; Busch, D.; Visekruna, A.; Slingerland, J.; Shouval, R.; Hiller, K.; van den Brink, M.; Pausch, P.; Neri, P.; Hudecek, M.; Poeck, H.; Luu, M.
10.1101/2024.08.19.608538 — immunology — Posted on 2024-09-13
3476 Macrophage-derived RNAseT2 stimulates muscle stem cell fusion via SLK/N-WASP/actin bundling
Weiss-Gayet, M.; Juban, G.; Le Moal, E.; Moretta, A.; Farnetari, C.; Gobet, C.; Guillemaud, J.; Le Bihan, M.-C.; Shoseyov, O.; Adrait, A.; Ternka, K.; Boespflug-Tanguy, O.; Kettwig, M.; Coute, Y.; Mounier, R.; Acquati, F.; Knight, R.; Chazaud, B.
10.1101/2024.09.11.612435 — cell biology — Posted on 2024-09-13
3478 Synergistic cross-kingdom host cell damage between Candida albicans and Enterococcus faecalis
Kapitan, M.; Niemiec, M. J.; Millet, N.; Brandt, P.; Chowdhury, M. E. K.; Czapka, A.; Abdissa, K.; Hoffmann, F.; Lange, A.; Veleba, M.; Nietzsche, S.; Mosig, A. S.; Loffler, B.; Marquet, M.; Makarewicz, O.; Kline, K. A.; Vylkova, S.; Swidergall, M.; Jacobsen, I. D.
10.1101/2024.09.11.612452 — microbiology — Posted on 2024-09-13
3481 Vaginal microbiota as a predictor of preterm birth: an observational cohort study
Lesimple, L.; Rousseau, J.; Plainvert, C.; Landraud, L.; Grall, N.; Goffinet, F.; Ancel, P.-Y.; Pannetier, C.; Poyart, C.; Mandelbrot, L.; Tazi, A.
10.1101/2024.09.11.612423 — microbiology — Posted on 2024-09-13
3482 Bullying and Early Brain Development: A Longitudinal Structural Magnetic Resonance Imaging Study from Adolescence to Early Adulthood
Connaughton, M.; Mitchell, O.; Cullen, E.; O'Connor, M.; Banaschewski, T.; Barker, G.; Bokde, A. L.; Bruhl, R.; Desrivieres, S.; Flor, H.; Garavan, H.; Gowland, P. A.; Grigis, A. A.; Heinz, A.; Lemaitre, H.; Martinot, J.-L.; Martinot, M.-L. P.; Artiges, E.; Nees, F.; Papadopoulos Orfanos, D.; Poustka, L.; Smolka, M. N.; Hohmann, S.; Holz, N. E.; Vaidya, N.; Walter, H.; Schumann, G.; Whelan, R.; Roddy, D.
10.1101/2024.09.11.611600 — neuroscience — Posted on 2024-09-13
3483 Human and bats genome robustness under COSMIC mutational signatures
Song, J.-H.; Zeng, Y.; Davalos, L. M.; MacCarthy, T.; Larijani, M.; Damaghi, M.
10.1101/2024.09.05.611453 — genomics — Posted on 2024-09-13
3484 Systematic review and meta-analysis of Hyalomma marginatum vertebrate hosts in the EU
Bah, M. T.; Vial, L.; Busani, L.; Souq, L.; Grosbois, V.; Bernard, C.; Jori, F.
10.1101/2024.09.11.612300 — ecology — Posted on 2024-09-13
3485 Precise Generation of Conformational Ensembles for Intrinsically Disordered Proteins via Fine-tuned Diffusion Models
Zhu, J.; Li, Z.; Zhang, B.; Zheng, Z.; Zhong, B.; Bai, J.; Hong, X.; Wang, T.; Wei, T.; Yang, J.; Chen, H.-F.
10.1101/2024.05.05.592611 — bioinformatics — Posted on 2024-09-13
3488 Molecular basis for the assembly of the Vps5-Vps17 SNX-BAR proteins with Retromer
Chen, K.-E.; Tillu, V. A.; Gopaldass, N.; Chowdhury, S. R.; Leneva, N.; Kovtun, O.; Ruan, J.; Guo, Q.; Ariotti, N.; Mayer, A.; Collins, B. M.
10.1101/2024.03.24.586500 — cell biology — Posted on 2024-09-13
3492 Brain state and cortical layer-specific mechanisms underlying perception at threshold
Morton, M. P.; Denagamage, S.; Blume, I. J.; Reynolds, J. H.; Jadi, M. P.; Nandy, A. S.
10.1101/2021.11.16.468866 — neuroscience — Posted on 2024-09-13
3493 Molecular basis of the urate transporter URAT1 inhibition by gout drugs
Suo, Y.; Fedor, J.; Zhang, H.; Tsolova, K.; Shi, X.; Sharma, K.; Kumari, S.; Borgnia, M. J.; Zhan, P.; Im, W.; Lee, S.-Y.
10.1101/2024.09.11.612563 — biophysics — Posted on 2024-09-12
3495 moPepGen: Rapid and Comprehensive Identification of Non-canonical Peptides
Zhu, C.; Liu, L. Y.; Ha, A.; Yamaguchi, T. N.; Zhu, H.; Hugh-White, R.; Livingstone, J.; Patel, Y.; Kislinger, T.; Boutros, P. C.
10.1101/2024.03.28.587261 — bioinformatics — Posted on 2024-09-13
3496 Multi-condition and multi-modal temporal profile inference during mouse embryonic development
Zhang, R.; Qiu, C.; Filippova, G.; Li, G.; Shendure, J.; Vert, J.-P.; Deng, X.; Disteche, C. M.; Noble, W. S.
10.1101/2024.03.03.583179 — bioinformatics — Posted on 2024-09-13
3497 A 96-Well Polyacrylamide Gel for Electrophoresis and Western Blotting
Birtwistle, M. R.; Huggins, J. R.; Zadeh, C. O.; Sarmah, D.; Srikanth, S.; Jones, B. K.; Cascio, L. N.; Dean, D. R.
10.1101/2024.05.10.593650 — biochemistry — Posted on 2024-09-13
3498 Nucleus accumbens dopamine release reflects Bayesian inference during instrumental learning
Qu, A. J.; Tai, L.-H.; Hall, C. D.; Tu, E. M.; Eckstein, M. K.; Mischanchuk, K.; Lin, W. C.; Chase, J. B.; MacAskill, A. F.; Collins, A. G. E.; Gershman, S. J.; Wilbrecht, L.
10.1101/2023.11.10.566306 — animal behavior and cognition — Posted on 2024-09-13
3500 Temporal dynamics of viral fitness and the adaptive immune response in HCV infection
Walker, M. R.; Leung, P.; Keoshkerian, E.; Pirozyan, M. R.; Lloyd, A.; Luciani, F.; Bull, R. A.
10.1101/2024.09.07.611784 — immunology — Posted on 2024-09-13
3501 Kisspeptin fiber and receptor distribution analysis suggests its potential role in central sensorial processing and behavioral state control
Zhang, L.; Hernandez, V. S.; Zetter, M. A.; Hernandez-Perez, O. R.; Hernandez Gonzalez, R.; Camacho-Arroyo, I.; Eiden, L. E.; Millar, R. P.
10.1101/2023.09.05.556375 — neuroscience — Posted on 2024-09-13
3502 Development of bright fluorescent auxin
Aoyama, T.; Nambo, M.; Yap, J. X.; Nakagawa, A.; Hayashi, M.; Ukai, Y.; Ohtsuka, M.; Hayashi, K.-i.; Sato, Y.; Tsuchiya, Y.
10.1101/2024.09.11.612572 — plant biology — Posted on 2024-09-13
3503 G3BP1 Maintains Vascular Endothelial Barrier Integrity by Negatively Regulating the MYD88-ARNO-ARF6 Signaling Pathway
Wen, B.; Sun, W.; Wu, H.; He, Y.; Chen, H.; Meng, Y.; Tang, G.; Zhu, J.; Wen, Z.; Wu, R.; Wu, G.; Zhang, C.; Chu, M.
10.1101/2024.09.09.612151 — physiology — Posted on 2024-09-13
3504 Myosin cluster dynamics determines epithelial wound ring constriction
Bhat, A.; Berthoz, R.; Lo Vecchio, S.; Spiegelhalter, C.; Yonemura, S.; Pertz, O.; Riveline, D.
10.1101/2024.09.12.612715 — biophysics — Posted on 2024-09-12
3507 Challenges in the Accurate Modelling of Lipid Dynamics in Monolayers and Bilayers
Tempra, C.; Chamorro, V. C.; Mandal, T.; Chiantia, S.; Vogele, M.; Fabian, B.; Javanainen, M.
10.1101/2024.09.12.612735 — biophysics — Posted on 2024-09-13
3508 PSMA-specific CAR-engineered macrophages for therapy of prostate cancer
Xu, Y.; Xie, D.; Cao, C.; Ju, Y.; Chen, X.; Guan, L.; Li, X.; Zhang, L.; Liang, C.; Yin, X.
10.1101/2024.09.07.611792 — bioengineering — Posted on 2024-09-12
3510 'Mitotic' kinesin-5 is a dynamic brake for axonal growth
Lu, W.; Lee, B. S.; Deng, H.; Lakonishok, M.; Martin-Blanco, E.; Gelfand, V. I.
10.1101/2024.09.12.612721 — cell biology — Posted on 2024-09-12
3511 Global proteomics indicates subcellular-specific anti-ferroptotic responses to ionizing radiation
Christopher, J. A.; Breckels, L. M.; Crook, O. M.; Vazquez-Chantada, M.; Barratt, D.; Lilley, K. S.
10.1101/2024.09.12.611851 — cell biology — Posted on 2024-09-12
3512 Age-dependent Changes in a Chaperone Complex in the Mouse Heart
Bhat, P. D.; Nalli, A.; Shoemaker, L.; Kwong, J. Q.; Krishnamurthy, P.; Benian, G. M.
10.1101/2024.09.12.612759 — cell biology — Posted on 2024-09-12
3514 Inflammation perturbs hematopoiesis by remodeling specific compartments of the bone marrow niche
Swann, J. W.; Zhang, R.; Verovskaya, E. V.; Calero-Nieto, F. J.; Wang, X.; Proven, M. A.; Shyu, P. T.; Guo, E.; Gottgens, B.; Passegue, E.
10.1101/2024.09.12.612751 — cell biology — Posted on 2024-09-13
3516 Adrenergic C1 neurons enhance anxiety via projections to PAG
Fernandez-Pena, C.; Pace, R. L.; Fernando, L. M.; Pittman, B. G.; Schwarz, L. A.
10.1101/2024.09.11.612440 — neuroscience — Posted on 2024-09-12
3517 Anatomically distinct regions in the inferior frontal cortex are modulated by task and reading skill
Stone, H. L.; Mitchell, J. L.; Fuentes-Jimenez, M.; Tran, J. E.; Yeatman, J. D.; Yablonski, M.
10.1101/2024.09.11.612349 — neuroscience — Posted on 2024-09-12
3518 Positive Allosteric Modulation of the α5-GABAA receptors prevents neuronal atrophy and cognitive decline independently of tau tangle accumulation in the PS19 mouse model
Dharavath, R. N.; Bernardo, A.; Marceau-Linhares, C.; Marcotte, M.; Wong, K.; Pina-Leblanc, C.; Bouchet, A.; Sharmin, D.; Cook, J.; Pandey, K. P.; Prevot, T. D.; Sibille, E.
10.1101/2024.09.07.611810 — neuroscience — Posted on 2024-09-12
3520 ARF degradation defines a deeply conserved step in auxin response
de Roij, M.; Hernandez Garcia, J.; Das, S.; Borst, J. W.; Weijers, D.
10.1101/2024.09.12.612472 — plant biology — Posted on 2024-09-12
3521 Symmetry of loop extrusion by dimeric SMC complexes is DNA-tension-dependent
Pradhan, B.; Pinto, A.; Kanno, T.; Tetiker, D.; Baaske, M. D.; Cutt, E.; Chatzicharlampous, C.; Schüler, H.; Deep, A.; Corbett, K. D.; Aragon, L.; Virnau, P.; Björkegren, C.; Kim, E.
10.1101/2024.09.12.612694 — biophysics — Posted on 2024-09-12
3522 A GAF domain mediates inositol pyrophosphate substrate channeling in PPIP5K phosphatases
Raia, P.; Lee, K.; Bartsch, S. M.; Rico-Resendiz, F.; Fiedler, D.; Hothorn, M.
10.1101/2024.09.12.612650 — biochemistry — Posted on 2024-09-12
3523 Sensitive dissection of a genomic regulatory landscape using bulk and targeted single-cell activation
Vucicevic, D.; Hsu, C.-W.; Lopez Zepeda, L. S.; Burkert, M.; Hirsekorn, A.; Bilic, I.; Kastelic, N.; Landthaler, M.; Lacadie, S. A.; Ohler, U.
10.1101/2024.09.12.612198 — genomics — Posted on 2024-09-12
3524 Genetic regulation of microRNAs in the older adult brain and their contribution to neuropsychiatric conditions
Vattathil, S. M.; Gerasimov, E. S.; Canon, S. M.; Lori, A.; Tan, S. S. M.; Kim, P. J.; Liu, Y.; Lai, E. C.; Bennett, D. A. C.; Wingo, T. S.; Wingo, A. P.
10.1101/2024.09.10.610174 — genetics — Posted on 2024-09-12
3526 Inhibition mediated by group III mGluRs regulates habenula activity and defensive behaviors
Ostenrath, A. M.; Faturos, N.; Ciftci Cobanoglu, Y. I.; Serneels, B.; Jeong, I.; Enz, A.; Hinrichsen, F.; Mutlu, A. K.; Bardenhewer, R.; Jetti, S. K.; Neuhauss, S. C. F.; Jurisch-Yaksi, N.; Yaksi, E.
10.1101/2024.09.11.612421 — neuroscience — Posted on 2024-09-12
3527 Nutrient starvation activates ECM remodeling gene enhancers associated with inflammatory bowel disease risk in fibroblasts
Secchia, S.; Beilinson, V.; Chen, X.; Yang, Z. F.; Wayman, J. A.; Dhaliwal, J.; Jurickova, I.; Angerman, E.; Denson, L. A.; Miraldi, E. R.; Weirauch, M. T.; Ikegami, K.
10.1101/2024.09.06.611754 — genomics — Posted on 2024-09-12
3528 Strategic targeting of Cas9 nickase expands tandem gene arrays
Takesue, H.; Okada, S.; Doi, G.; Sugiyama, Y.; Kusumoto, E.; Ito, T.
10.1101/2024.09.10.612242 — genomics — Posted on 2024-09-12
3534 Biantennary N-glycans As Receptors for MARTX Toxins in Vibrio Pathogenesis
Chen, J.; Goerdeler, F.; Jaroentomeechai, T.; Hernandez, F. X. S.; Wang, X.; Clausen, H.; Narimatsu, Y.; Satchell, K. J.
10.1101/2024.09.12.611726 — microbiology — Posted on 2024-09-12
3535 Comprehensive intra-host infection kinetics reveals high arbo-flavivirus transmission potential by neglected vector species, Aedes scutellaris
Samung, Y.; Pengon, J.; Pethrak, C.; Pakparnich, P.; Thaiudomsup, S.; Suksirisawat, K.; Phayakkaphol, A.; Eiamsam-ang, S.; Phanitchat, T.; Sartsanga, C.; Jantra, T.; Sriwichai, P.; Jupatanakul, N.
10.1101/2024.09.12.612593 — microbiology — Posted on 2024-09-12
3536 pr-independent biogenesis of infectious mature Zika virus particles
Dowd, K. A.; Schroeder, M.; Sanchez, E.; Brumbaugh, B.; Foreman, B. M.; Burgomaster, K. E.; Shi, W.; Wang, L.; Caputo, N.; Gordon, D.; Schwartz, C. L.; Hansen, B. T.; Aleshnick, M.; Kong, W.-P.; Morabito, K. M.; Hickman, H. D.; Graham, B. S.; Fischer, E. R.; Pierson, T. C.
10.1101/2024.09.12.612520 — microbiology — Posted on 2024-09-12
3539 A KCa 2.2/2.3 opener reverses ET-1 induced NLRP3 activation in hypertensive mice
Sobrano Fais, R.; Comerma Steffensen, S. G.; Pinilla, E.; Matchkov, V. V.; Tostes, R. C.; Carneiro, F. S.; Simonsen, U.
10.1101/2024.09.06.611748 — pharmacology and toxicology — Posted on 2024-09-12
3540 Coagulation factor XII contributes to renin activation, heart failure progression, and mortality
Gladysheva, I. P.; Sullivan, R. D.; Saleem, S.; Castellino, F. J.; Ploplis, V. A.; Reed, G. L.
10.1101/2024.09.06.611753 — pathology — Posted on 2024-09-12
3541 Stress-mediated growth determines E. coli division site morphogenesis
Pelech, P.; Navarro, P. P.; Vettiger, A.; Chao, L. H.; Allolio, C.
10.1101/2024.09.11.612282 — biophysics — Posted on 2024-09-12
3543 Improving Functional Muscle Regeneration in Volumetric Muscle Loss Injuries by Shifting the Balance of Inflammatory and Pro-Resolving Lipid Mediators
Turner, T. C.; Pittman, F. S.; Zhang, H.; Hymel, L. A.; Zheng, T.; Behara, M.; Anderson, S. E.; Andraca Harrer, J.; Link, K. A.; Ahammed, M. A.; Maner-Smith, K.; Liu, X.; Yin, X.; Lim, H. S.; Spite, M.; Qiu, P.; Garcia, A. J.; Mortensen, L. J.; Jang, Y. C.; Willett, N. J.; Botchwey, E. A.
10.1101/2024.09.06.611741 — bioengineering — Posted on 2024-09-12
3548 Analysis of polyclonal and monoclonal antibody to the influenza virus nucleoprotein in different oligomeric states
Myers, M. L.; Conlon, M. T.; Gallagher, J. R.; Woolfork, D. D.; Khorrami, N. D.; Park, W. B.; Stradtman-Carvalho, R. K.; Harris, A. K.
10.1101/2024.09.12.612748 — microbiology — Posted on 2024-09-12
3550 Glyco-phenotyping of mutants of Lacticaseibacillus paracasei by lectin microarray
Suzuki, E.; Serata, M.; Sako, T.; Sato, S.; Iino, T.; Tateno, H.; Hirabayashi, J.
10.1101/2024.09.11.612535 — microbiology — Posted on 2024-09-12
3552 Assessing the performance of TRX and DUF148 antigens for detection of prepatent Guinea worm (Dracunculus medinensis) infection in dogs
Hakimi, H.; Weerarathne, P.; Saleh, M. N.; Rech, R. R.; Ngandolo Bongo Nare, R. R.; Ouakou Tchindebet, P. R.; Metinou, S. K.; Tritten, L.; Verocai, G. G.
10.1101/2024.09.12.612594 — microbiology — Posted on 2024-09-12
3553 Immunological findings of West Caucasian bat virus in an accidental host
Castellan, M.; Zamperin, G.; Foiani, G.; Zorzan, M.; Priore, M. F.; Drzewniokova, P.; Melchiotti, E.; Vascellari, M.; Monne, I.; Crovella, S.; Leopardi, S.; De Benedictis, P.
10.1101/2024.09.12.612599 — microbiology — Posted on 2024-09-12
3554 An archaeal CBASS system eliminates viruses without killing the host cells
Choudhary, D. K.; Singla, H.; Vassover, D.; Golan, N.; Reshef, L.; Dubunsky, V.; Gophna, U.
10.1101/2024.09.12.612678 — microbiology — Posted on 2024-09-12
3555 Unlocking hidden phage diversity to complete the BASEL collection for systematic exploration of phage-host interactions
Humolli, D.; Maffei, E.; Heyer, Y.; Agustoni, E.; Piel, D.; Shaidullina, A.; Willi, L.; Sauer, P.; Estermann, F.; Cuenod, A.; Buser, D. P.; Egli, A.; Hiller, S.; Dunne, M.; Harms, A.
10.1101/2024.09.12.612763 — microbiology — Posted on 2024-09-12
3556 Context-Seq: CRISPR-Cas9 Targeted Nanopore Sequencing for Transmission Dynamics of Antimicrobial Resistance
Fuhrmeister, E. R.; Kim, S.; Mairal, S. A.; McCormack, C.; Chieng, B.; Swarthout, J. M.; Paulos, A. H.; Njenga, S. M.; Pickering, A. J.
10.1101/2024.09.12.612745 — microbiology — Posted on 2024-09-12
3558 Protein identification using cryo-EM and artificial intelligence guides improved sample purification
Carr, K. D.; Zambrano, D. E. D.; Weidle, C.; Goodson, A.; Eisenach, H. E.; Pyles, H.; Courbet, A.; King, N. P.; Borst, A. J.
10.1101/2024.09.11.612515 — biochemistry — Posted on 2024-09-12
3559 The epitranscriptomic m6A RNA modification modulates synaptic function in ageing and in a mouse model of synucleinopathy
Chopra, A.; Xylaki, M.; Yin, F.; Castro-Hernandez, R.; Merghani, M.; Grande, V.; Mollenhauer, B.; Fischer, A.; Outeiro, T. F.
10.1101/2024.09.12.612649 — neuroscience — Posted on 2024-09-12
3560 Integration of binocular vision and motor state to promote prey pursuit
Tian, G.; Lam, T. K. C.; Yan, G.; He, Y.; Khan, B.; Qu, J.; Semmelhack, J. L.
10.1101/2024.09.08.611846 — neuroscience — Posted on 2024-09-12
3562 Multiple mechanisms of action of an extremely painful venom
Borjon, L. J.; de Assis Ferreira, L. C.; Trinidad, J. C.; Sasic, S.; Hohmann, A. G.; Tracey, W. D.
10.1101/2024.09.12.612741 — neuroscience — Posted on 2024-09-12
3564 Driver lines for studying associative learning in Drosophila
Shuai, Y.; Sammons, M.; Sterne, G. R.; Hibbard, K.; Yang, H.; Yang, C.-P.; Managan, C.; Siwanowicz, I.; Lee, T.; Rubin, G. M.; Turner, G. C.; Aso, Y.
10.1101/2023.09.15.557808 — neuroscience — Posted on 2024-09-12
3566 Novel Role of Endothelial CD45 in Regulating Endothelial-to-Mesenchymal Transition in Atherosclerosis
Peng, Q.; Arulsamy, K.; Lu, Y. W.; Wu, H.; Zhu, B.; Singh, B.; Cui, K.; Wylie-Sears, J.; Li, K. S.; Wong, S.; Cowan, D. B.; Aikawa, M.; Wang, D.-Z.; Bischoff, J.; Chen, K.; Chen, H.
10.1101/2024.09.03.610974 — cell biology — Posted on 2024-09-12
3570 Volume electron microscopy reveals 3D synaptic nanoarchitecture in postmortem human prefrontal cortex
Glausier, J. R.; Bouchet-Marquis, C.; Maier, M.; Banks-Tibbs, T.; Wu, K.; Ning, J.; Melchitzky, D.; Lewis, D. A.; Freyberg, Z. A.
10.1101/2024.02.26.582174 — neuroscience — Posted on 2024-09-12
3572 Columnar cholinergic neurotransmission onto T5 cells of Drosophila
Samara, E.; Schilling, T.; Ribeiro, I. M. A.; Haag, J.; Leonte, M.-B.; Borst, A.
10.1101/2024.08.28.610055 — neuroscience — Posted on 2024-09-12
3573 Small ARF-like 2 GTPase TITAN 5 is linked with the dynamic regulation of IRON-REGULATED TRANSPORTER 1
Mohr, I.; Eutebach, M.; Knopf, M. C.; Schommen, N.; Gratz, R.; Angrand, K.; Genders, L.; Brumbarova, T.; Bauer, P.; Ivanov, R.
10.1101/2023.04.27.538571 — plant biology — Posted on 2024-09-12
3574 Bacterial stress granule protects mRNA through ribonucleases exclusion
Pei, L.; Xian, Y.; Yan, X.; Schaefer, C.; Syeda, A. H.; Howard, J.; Liao, H.; Bai, F.; Leake, M. C.; Pu, Y.
10.1101/2024.04.27.591437 — biophysics — Posted on 2024-09-12
3576 zol & fai: large-scale targeted detection and evolutionary investigation of gene clusters
Salamzade, R.; Tran, P. Q.; Martin, C.; Manson, A. L.; Gilmore, M. S.; Earl, A. M.; Anantharaman, K.; Kalan, L.
10.1101/2023.06.07.544063 — bioinformatics — Posted on 2024-09-12
3578 Transdermal Electrophysiological Recordings of Diabetic Small Fiber Peripheral Neuropathy Using a Needle Electrode Array in Mice and Men
Blaszkiewicz, M.; Caron, L.; Villinski, B.; Passarelli, J.; Donnelly, J.; Towne, J. M.; Story, N. M.; Merchant, E.; Khan, F. S.; Emanetoglu, N.; Kass, L.; Smith, R. L.; Townsend, K. L.
10.1101/2023.03.03.530993 — bioengineering — Posted on 2024-09-12
3584 Acute dietary methionine restriction highlights sensitivity of neocortex development to metabolic variations
Saha, S.; Debacq, C.; Audouard, C.; Jungas, T.; Dupre, P.; Fawal, M. A.; Chapat, C.; Michaud, H.-A.; Le Cam, L.; Lacroix, M.; Ohayon, D.; Davy, A.
10.1101/2024.09.10.612174 — developmental biology — Posted on 2024-09-12
3585 The fission yeast SUMO-targeted Ubiquitin Ligase Slx8 functionally associates with clustered centromeres and the silent mating type region at the nuclear periphery
Chakraborty, S.; Strachan, J.; Schirmeisen, K.; Besse, L.; Mercier, E.; Freon, K.; Zhang, H.; Zhao, N.; Bayne, E.; Lambert, S. A.
10.1101/2024.09.10.612319 — cell biology — Posted on 2024-09-12
3586 Phosphatase-independent suppression of mucosal inflammation and disease progression by Salmonella SopB
Diab, N.; Stange, E. L.; Yong, C. H.; Deiwick, J.; Vucur, M.; Luedde, T.; Hensel, M.; Torow, N.; Zhang, K.; Hornef, M. W.
10.1101/2024.09.02.610793 — microbiology — Posted on 2024-09-12
3587 A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective and anti-inflammatory properties following status epilepticus in mice
Ferhat, L.; Soussi, R.; Masse, M.; Kyriatzis, G.; Girard, S.; Gassiot, F.; Gaudin, N.; Laurencin, M.; Bernard, A.; Bole, A.; Ferracci, G.; Smirnova, M.; Roman, F.; Dive, V.; Cisternino, S.; Temsamani, J.; David, M.; Lecorche, P.; Jacquot, G.; KHRESTCHATISKY, M.
10.1101/2024.07.15.603208 — neuroscience — Posted on 2024-09-12
3589 Predictive Coding of Reward in the Hippocampus
Yaghoubi, M. H.; Nieto-Pasadas, A.; Mosser, C.-A.; Gisiger, T.; Wilson, E.; Williams, S.; Brandon, M. P.
10.1101/2024.09.03.611040 — neuroscience — Posted on 2024-09-12
3590 Dual-color optical activation and suppression of neurons with high temporal precision
Mermet-Joret, N.; Moreno, A.; Zbela, A.; Nazari, M.; Ellendersen, B. E.; Comaposada- Baro, R.; Krauth, N.; von Philipsborn, A.; Sorensen, A. T.; Piriz, J.; Lin, J. Y.; Nabavi, S.
10.1101/2021.05.05.442824 — neuroscience — Posted on 2024-09-12
3593 Disrupted Hippocampal Theta-Gamma Coupling and Spike-Field Coherence Following Experimental Traumatic Brain Injury
Adam, C. D.; Mirzakhalili, E.; Gagnon, K. G.; Cottone, C.; Arena, J. D.; Ulyanova, A. V.; Johnson, V. E.; Wolf, J. A.
10.1101/2024.05.30.596704 — neuroscience — Posted on 2024-09-12
3596 Spontaneously regenerative corticospinal neurons in mice
Fait, B. W.; Cotto, B.; Murakami, T. C.; Hagemann-Jensen, M.; Zhan, H.; Freivald, C.; Turbek, I.; Gao, Y.; Yao, Z.; Way, S. W.; Zeng, H.; Tasic, B.; Steward, O.; Heintz, N.; Schmidt, E. F.
10.1101/2024.09.09.612115 — neuroscience — Posted on 2024-09-12
3599 Mapping the gene space at single-cell resolution with gene signal pattern analysis
Venkat, A.; Leone, S.; Youlten, S. E.; Fagerberg, E.; Attanasio, J.; Joshi, N. S.; Perlmutter, M.; Krishnaswamy, S.
10.1101/2023.11.26.568492 — bioinformatics — Posted on 2024-09-12
3601 The relationship between gut and nasopharyngeal microbiome composition can predict the severity of COVID-19
Martin-Castano, B.; Diez-Echave, P.; Garcia-Garcia, J.; Hidalgo-Garcia, L.; Ruiz-Malagon, A. J.; Molina-Tijeras, J. A.; Rodriguez-Sojo, M. J.; Redruello-Romero, A.; Martinez-Zaldivar, M.; Mota, E.; Cobo, F.; Diaz-Villamarin, X.; Fernandez-Varon, E.; Alvarez-Estevez, M.; Garcia, F.; Morales-Garcia, C.; Merlos, S.; Garcia-Flores, P.; Colmenero-Ruiz, M.; Ruiz-Sancho, A.; Nunez, M.; Rodriguez-Cabezas, M. E.; Carazo, A.; Martin, J.; Moron, R.; Rodriguez, A.; Galvez, J.
10.1101/2024.01.11.575201 — microbiology — Posted on 2024-09-12
3602 Adjuvant conditioning shapes the adaptive immune response and promotes trained immunotolerance via NLRP3/IL-1
Boccia, T.; Pan, W.; Fattori, V.; Cervantes-Diaz, R.; Rogers, M. S.; Zanoni, I.; Cuenca, A. G.
10.1101/2024.09.06.611736 — immunology — Posted on 2024-09-12
3603 SARS-CoV-2 spike antibodies cross-react with dengue virus and enhance infection in-vitro and in-vivo
Jakhar, K.; Sonar, S.; Singh, G.; Asuru, T. R.; Joshi, G.; Beniwal, N.; Sarkar, T.; Tiwari, M.; Kaur, J.; Rathore, D. K.; Lal, B.; Kumar, S.; Srivastav, P.; Kumar, S.; Phagna, V.; Sushma, ; Kumar, L.; Gupta, V.; Kshetrapal, P.; Singh, S.; Wadhwa, N.; Thiruvengadam, R.; Raghavan, S.; Gosain, M.; Shrivastava, T.; Bhattacharyya, S.; Asthana, S.; Guchhait, P.; Mani, S.
10.1101/2023.10.09.557914 — immunology — Posted on 2024-09-12
3604 Role of ERK2 dimerization in synaptic plasticity and memory
Ojea Ramos, S.; Medina, C.; Krwczyk, M. d. C.; Millan, J.; Romano, A.; Baez, M. V.; Urbano, F.; Boccia, M. M.; Feld, M.
10.1101/2024.09.06.611755 — neuroscience — Posted on 2024-09-12
3605 Distinct input-specific mechanisms enable presynaptic homeostatic plasticity
Chien, C.; He, K.; Perry, S.; Tchitchkan, E.; Han, Y.; Li, X.; Dickman, D.
10.1101/2024.09.10.612361 — neuroscience — Posted on 2024-09-12
3608 Burning glass effect of water droplets triggers an ER-derived calcium response in the chloroplast stroma of Arabidopsis thaliana leaves
Kuang, D.; Romand, S.; Zvereva, A. S.; Marchesano, B. M.; Buratti, S.; Zheng, K.; Mylle, E.; Spetea Wiklund, C.; Van Damme, D.; Wurzinger, B.; Schwarzlander, M.; Teige, M.; Costa, A.; Stael, S.
10.1101/2024.09.07.611817 — plant biology — Posted on 2024-09-12
3609 Vesicle docking and fusion pore modulation by the neuronal calcium sensor Synaptotagmin-1
Tsemperouli, M.; Kumar Cheppali, S.; Rivera Molina, F.; Chetrit, D.; Landajuela, A.; Toomre, D.; Karatekin, E.
10.1101/2024.09.12.612660 — biophysics — Posted on 2024-09-12
3611 Dynamic imaging of myelin pathology in physiologically preserved human brain tissue using third harmonic generation microscopy
Meijns, N.; Blokker, M.; Idema, S.; t' Hart, B. A.; Veta, M.; Ettema, L.; van Iersel, J.; Zhang, Z.; Schenk, G.; Groot, M.; Luchicchi, A.
10.1101/2024.09.06.611764 — neuroscience — Posted on 2024-09-12
3612 Association between maternal depressive symptoms and hair cortisol concentration during pregnancy with corpus callosum integrity in newborns
Mariani Wigley, I. L. C.; Mustonen, P.; Karlsson, L.; Nolvi, S.; Scheinin, N.; Kortesluoma, S.; Pastore, M.; Tervahartiala, K.; Coimbra, B.; Rodrigues, A. J.; Sousa, N.; Karlsson, H.; Tuulari, J. J.
10.1101/2024.09.06.610927 — neuroscience — Posted on 2024-09-12
3616 Caspase-2 kills cells with extra centrosomes
Rizzotto, D.; Vigorito, V.; Rieder, P.; Gallob, F.; Moretta, G. M.; Soratroi, C.; Riley, J.; Bellutti, F.; Li Veli, S.; Mattivi, A.; Lohmueller, M.; Herzog, S.; Bornhauser, B. C.; Jacotot, E. D.; Villunger, A.; Fava, L. L.
10.1101/2024.02.13.580097 — cell biology — Posted on 2024-09-12
3618 The transcription factor Traffic jam orchestrates the somatic piRNA pathway in Drosophila ovaries
Alizada, A.; Martins, A.; Mouniee, N.; Suarez, J. R.; Bertin, B.; Gueguen, N.; Mirouse, V.; Mehouas, S. M.; Rivera, A. J.; Lau, N. C.; Hannon, G. J.; Nicholson, B. C.; Brasset, E.
10.1101/2024.09.10.612307 — molecular biology — Posted on 2024-09-12
3623 Additions to the list of arthropods of Reunion Island
Nibouche, S.; Sadeyen, J.; Dervin, S.; Gauche, M.; Merion, S.; Minatchy, J.; Fontaine, R.; Reynaud, P.; Michel, B.
10.1101/2024.09.03.610934 — zoology — Posted on 2024-09-12
3625 Multifunctional polymerization domains determine the onset of epigenetic silencing in Arabidopsis
Schulten, A.; Jang, G.-J.; Payne-Dwyer, A.; Fiedler, M.; Nielsen, M. L.; Bienz, M.; Leake, M. C.; Dean, C.
10.1101/2024.02.15.580496 — plant biology — Posted on 2024-09-12
3626 TIPE drives a cancer stem-like phenotype by promoting glycolysis via PKM2/HIF-1alpha axis in melanoma
Tian, M.; Yang, L.; Zhao, Z.; Li, J.; Wang, L.; Yin, Q.; Hu, W.; Lou, Y.; Du, J.; Zhao, P.
10.1101/2023.11.14.567124 — cancer biology — Posted on 2024-09-12
3628 Stochasticity in dietary restriction-mediated lifespan outcomes in Drosophila
Mosley, O. L.; Villa, J. A.; Kamalakkannan, A.; James, E.; Hoffman, J. M.; Lyu, Y.
10.1101/2024.09.06.611756 — genetics — Posted on 2024-09-12
3631 Differential interference with actin-binding protein function by acute Cytochalasin B
Lambert, C.; Karger, M.; Steffen, A.; Tang, Y.; Doering, H.; Stradal, T. E. B.; Lappalainen, P.; Faix, J.; Bieling, P.; Rottner, K.
10.1101/2024.09.11.611976 — cell biology — Posted on 2024-09-12
3637 Long-term live imaging, cell identification and cell tracking in regenerating crustacean legs
Cevrim, C.; Laplace-Builhe, B.; Sugawara, K.; Rusciano, M. L.; Labert, N.; Brocard, J.; Almazan, A.; Averof, M.
10.1101/2024.09.11.612529 — developmental biology — Posted on 2024-09-12
3638 Toxoplasma gondii infection misdirects placental trophoblast lineage specification
Cabo, L. F.; Yang, L.; Gao, M.; da Silva, R. J.; Washington, N. N.; Reilly, S. M.; Megli, C. J.; Coyne, C. B.; Boyle, J. P.
10.1101/2024.09.10.612241 — developmental biology — Posted on 2024-09-12
3639 The oocyte zinc transporter Slc39a10/Zip10 is a regulator of zinc sparks during fertilization in mice.
Kageyama, A.; Ogonuki, N.; Wakai, T.; Namiki, T.; Kawata, Y.; Ozawa, M.; Yamada, Y.; Fukada, T.; Ogura, A.; Fissore, R. A.; Kashiwazaki, N.; Ito, J.
10.1101/2024.09.11.612381 — developmental biology — Posted on 2024-09-12
3643 Autism and Intellectual Disability-Associated MYT1L Mutation Alters Human Cortical Interneuron Differentiation, Maturation, and Physiology
Prakasam, R.; Determan, J.; Narasimhan, M.; Shen, R.; Saleh, M.; Chapman, G.; Kaushik, K.; Gontarz, P.; Meganathan, K.; Hakim, B.; Zhang, B.; Huettner, J. E.; Kroll, K. L.
10.1101/2024.09.11.612541 — developmental biology — Posted on 2024-09-12
3646 Integrated single-cell atlas of human atherosclerotic plaques
Traeuble, K.; Munz, M.; Pauli, J.; Sachs, N.; Vafadarnejad, E.; Carrillo-Roa, T.; Maegdefessel, L.; Kastner, P.; Heinig, M.
10.1101/2024.09.11.612431 — cell biology — Posted on 2024-09-12
3647 Proteostasis and metabolic dysfunction in a distinct subset of storage-induced senescent erythrocytes targeted for clearance
Peltier, S.; Marin, M.; Dzieciatkowska, M.; Dussiot, M.; Roy, M.; Bruce, J.; Leblanc, L.; Hadjou, Y.; Georgeault, S.; Fricot, A.; Roussel, C.; Stephenson, D.; Casimir, M.; Sissoko, A.; Paye, F.; Dokmak, S.; Ndour, P. A.; Roingeard, P.; Gautier, E.-F.; Spitalnik, S.; Hermine, O.; Buffet, P. A.; D'Alessandro, A.; Amireault, P.
10.1101/2024.09.11.612195 — cell biology — Posted on 2024-09-12
3648 Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegeneration
Lane, A. R.; Scher, N. E.; Bhattacharjee, S.; Zlatic, S. A.; Roberts, A. M.; Gokhale, A.; Singleton, K. S.; Duong, D. M.; McKenna, M.; Liu, W. L.; Baiju, A.; Moctezuma, F. G. R.; Tran, T.; Patel, A.; Clayton, L. B.; Petris, M. J.; Wood, L. B.; Patgiri, A.; Vrailas-Mortimer, A. D.; Cox, D. N.; Roberts, B. R.; Werner, E.; Faundez, V.
10.1101/2024.09.09.612106 — neuroscience — Posted on 2024-09-12
3649 Maternal obesogenic diet disrupts mid-gestation decidual immune and vascular homeostasis without impairing spiral artery remodelling
Bellissimo, C. J.; Yeo, E.; Ribeiro, T. A.; Jazwiec, P. A.; Ellewela, C.; Bains, J.; Ashkar, A. A.; Beristain, A. G.; Bowdish, D. M. E.; Sloboda, D. M.
10.1101/2024.09.10.612284 — developmental biology — Posted on 2024-09-12
3650 ABHD11 mediated deglutarylation regulates the TCA cycle and T cell metabolism
Grice, G. L.; Minogue, E.; Coates, H. W.; Debela, M.; Kaneider-Kaser, N.; Antrobus, P. R.; Johnson, R. S.; Nathan, J. A.
10.1101/2024.09.11.612392 — cell biology — Posted on 2024-09-12
3653 Adaptive arousal regulation: Pharmacologically shifting the peak of the Yerkes-Dodson curve by catecholaminergic enhancement of arousal
Beerendonk, L.; Mejias, J. F.; Nuiten, S. A.; de Gee, J. W.; Zantvoord, J. B.; Fahrenfort, J. J.; van Gaal, S.
10.1101/2024.09.11.612196 — neuroscience — Posted on 2024-09-12
3655 A transcription factor quintet orchestrating bundle sheath expression in rice
Hua, L.; Wang, N.; Stanley, S.; Donald, R.; Kumar Eeda, S.; Billakurthi, K.; Borba, A. R.; Hibberd, J. M.
10.1101/2024.06.17.599020 — plant biology — Posted on 2024-09-12
3657 Evolution of the Cdk4/6-Cdkn2 system in invertebrates
Yuki, S.; Sasaki, S.; Yamamoto, Y.; Murakami, F.; Sakata, K.; Araki, I.
10.1101/2024.05.26.595977 — evolutionary biology — Posted on 2024-09-12
3660 Widespread naturally variable human exons aid genetic interpretation
Jacobs, H.; Gorissen, B.; Guez, J.; Kanai, M.; Finucane, H.; Burge, C.
10.1101/2024.09.09.612029 — genetics — Posted on 2024-09-11
3661 Linking ringed seal foraging behaviour to environmental variability
Nykänen, M.; Niemi, M.; Biard, V.; Carter, M. I. D.; Pirotta, E.; Kunnasranta, M.
10.1101/2024.09.09.611181 — ecology — Posted on 2024-09-11
3663 Axin1 and Axin2 regulate the WNT-signaling landscape to promote distinct mesoderm programs
Hernandez-Martinez, R.; Nowotschin, S.; Harland, L. T. G.; Kuo, Y.-Y.; Theeuwes, B.; Göttgens, B.; Lacy, E.; Hadjantonakis, A.-K.; Anderson, K. V.
10.1101/2024.09.11.612342 — developmental biology — Posted on 2024-09-11
3664 The Cardioprotective Role of Neutrophil-Specific STING in Myocardial Ischemia/Reperfusion Injury
Brockman, M. L.; Scruggs, T. A.; Wang, L.; Kabboul, G.; Calvert, J. W.; Levit, R. D.
10.1101/2024.09.06.611551 — immunology — Posted on 2024-09-11
3665 Filter-based models of suppression in retinal ganglion cells: comparison and generalization across species and stimuli
Shahidi, N.; Rozenblit, F.; Khani, M. H.; Schreyer, H. M.; Mietsch, M.; Protti, D. A.; Gollisch, T.
10.1101/2022.12.01.518577 — neuroscience — Posted on 2024-09-11
3671 Integrated genomic analysis of NF1-associated peripheral nerve sheath tumors: an updated biorepository dataset
Banerjee, J.; Lyu, Y.; Makri, S. C.; Scott, A. J.; Zhang, L.; Calizo, A.; Pollard, K.; Yang, K.; Gross, J. M.; Wang, J.; Levin, A. S.; Belzberg, A. J.; Romo, C. G.; Allaway, R. J.; Blakeley, J. O.; Hirbe, A. C.; Pratilas, C. A.
10.1101/2024.01.23.576977 — bioinformatics — Posted on 2024-09-11
3675 ChatNT: A Multimodal Conversational Agent for DNA, RNA and Protein Tasks
Richard, G.; de Almeida, B. P.; Dalla-Torre, H.; Blum, C.; Hexemer, L.; Pandey, P.; Laurent, S.; Lopez, M. P.; Laterre, A.; Lang, M.; Sahin, U.; Beguir, K.; Pierrot, T.
10.1101/2024.04.30.591835 — genomics — Posted on 2024-09-11
3676 Zebrafish models of human-duplicated gene SRGAP2 reveal novel functions in microglia and visual system development
Uribe-Salazar, J. M.; Kaya, G.; Weyenberg, K. B.; Radke, B.; Hino, K. K.; Soto, D. C.; Shiu, J.-L.; Zhang, W.; Ingamells, C.; Haghani, N. K.; Xu, E.; Rosas, J.; Simo, S.; Miesfeld, J.; Glaser, T.; Baraban, S. C.; Jao, L.-E. C.; Dennis, M. Y.
10.1101/2024.09.11.612570 — genomics — Posted on 2024-09-11
3677 The roles of isolation and interspecific interaction in generating the functional diversity of an insular mammal radiation
Nations, J. A.; Kohli, B. A.; Handika, H.; Achmadi, A. S.; Polito, M. J.; Rowe, K. C.; Esselstyn, J. A.
10.1101/2022.07.15.500274 — ecology — Posted on 2024-09-11
3679 Novel Pannexin 1 isoform is increased in cancer
O'Donnell, B. L.; Stefan, D.; Chiu, Y.-H.; Zeitz, M.; Tang, J.; Johnston, D.; Leighton, S.; Van Kessell, C.; Barr, K.; Gyenis, L.; Freeman, T.; Kelly, J. J.; Sayedyahossein, S.; Litchfield, D. W.; Roth, K.; Smyth, J. W.; Hebb, M.; Ronald, J.; Bayliss, D. A.; Penuela, S.
10.1101/2024.09.09.612143 — cell biology — Posted on 2024-09-11
3680 Anti-phase clustering of regulatory factors shapes gene bursting
Li, B.; Wong, Y. Y.; Flores-Rodriguez, N.; Davidson, T.; Graus, M. S.; Smialkovska, V.; Ohishi, H.; Feldmann, A.; Ochiai, H.; Francois, M.
10.1101/2024.09.10.612363 — molecular biology — Posted on 2024-09-11
3683 The functional role of locus coeruleus microglia in the female stress response
Smiley, C. E.; Pate, B. S.; Bouknight, S. J.; Harrington, E. N.; Jasnow, A. M.; Wood, S. K.
10.1101/2024.01.10.575076 — neuroscience — Posted on 2024-09-11
3686 Intergenerational transmission of the structure of the auditory cortex and reading skills
Kepinska, O.; Bouhali, F.; Degano, G.; Berthele, R.; Tanaka, H.; Hoeft, F.; Golestani, N.
10.1101/2024.09.11.610780 — neuroscience — Posted on 2024-09-11
3692 Molecular mechanisms of uric acid transport by the native human URAT1 and its inhibition by anti-gout drugs
Wu, C.; Zhang, C.; Jin, S.; Wang, J. J.; Dai, A.; Xu, J.; Zhang, H.; Yang, X.; He, X.; Yuan, Q.; Hu, W.; Xu, Y.; Wang, M.-W.; Jiang, Y.; Yang, D.; Xu, H. E.
10.1101/2024.09.11.612394 — biochemistry — Posted on 2024-09-11
3694 The paradox of extremely fast evolution driven by genetic drift in multi-copy gene systems
Wang, X.; Ruan, Y.; Zhang, L.; Chen, X.; Shi, Z.; Wang, H.; Chen, B.; Tracy, M. E.; Wu, C.-I.; Wen, H.
10.1101/2023.06.14.545040 — evolutionary biology — Posted on 2024-09-11
3695 MIXL1 Activation in Endoderm Differentiation ofHuman Induced Pluripotent Stem Cells
Osteil, P.; Withey, S.; Santucci, N.; Aryamanesh, N.; Pang, C. N. I.; Salehin, N.; Sun, J.; Qin, A.; Su, J.; Knowles, H.; Cai, Z.; Li, X. B.; Wolvetang, E. J.; Tam, P. P. L.
10.1101/2024.03.06.583475 — developmental biology — Posted on 2024-09-11
3696 Constitutively active receptor ADGRA3 signaling induces adipose thermogenesis
Zhao, Z.; Hu, L.; Song, B.; Jiang, T.; Wu, Q.; Lin, J.; Li, X.; Cai, Y.; Li, J.; Qian, B.; Liu, S.; Lang, J.; Yang, Z.
10.1101/2024.06.08.598066 — cell biology — Posted on 2024-09-11
3697 The RNA helicase HrpA rescues collided ribosomes in E. coli
Campbell, A.; Esser, H. F.; Burroughs, A. M.; Berninghausen, O.; Aravind, L.; Becker, T.; Green, R.; Beckmann, R.; Buskirk, A. R.
10.1101/2024.09.11.612461 — molecular biology — Posted on 2024-09-11
3698 The transmembrane glycoprotein Gpnmb is required for the immune and fibrotic responses during zebrafish heart regeneration
Gupta, S.; Bajwa, G. K.; El-Sammak, H.; Mattonet, K.; Gunther, S.; Looso, M.; Stainier, D. Y. R.; Marin-Juez, R.
10.1101/2024.09.11.612527 — molecular biology — Posted on 2024-09-11
3700 The Role of Thermal Stability in AAV Titration of Engineered Variants
Zin, E. A.; Desrosiers, M.; Ocari, T.; Labernede, G.; Robert, C.; Izabella, C.; Saubamea, B.; Ferrari, U.; Dalkara, D.
10.1101/2024.09.11.612416 — molecular biology — Posted on 2024-09-11
3702 flt1 inactivation promotes zebrafish cardiac regeneration by enhancing endothelial activity and limiting the fibrotic response
Wang, Z.; Mehra, A.; Wang, Q.-C.; Gupta, S.; Ribeiro da Silva, A.; Juan, T.; Gunther, S.; Detleffsen, J.; Looso, M.; Stainier, D. Y. R.; Marin-Juez, R.
10.1101/2024.09.11.612516 — molecular biology — Posted on 2024-09-11
3705 Symbiont loss and gain, rather than co-diversification shapes honeybee gut microbiota diversity and function
Prasad, A.; Pallujam, A. D.; Siddaganga, R.; Suryanarayanan, A.; Mazel, F.; Brockmann, A.; Yek, S. H.; Engel, P.
10.1101/2024.09.11.612390 — microbiology — Posted on 2024-09-11
3706 A genome-wide One Health study of Klebsiella pneumoniae in Norway reveals overlapping populations but few recent transmission events across reservoirs
Hetland, M. A. K.; Winkler, M. A.; Kaspersen, H.; Hakonsholm, F.; Bakksjo, R.-J.; Bernhoff, E.; Delgado-Blas, J. F.; Brisse, S.; Correia, A.; Fostervold, A.; Lam, M. M. C.; Lunestad, B.-T.; Marathe, N. P.; Raffelsberger, N.; Samuelsen, O.; Sunde, M.; Sundsfjord, A.; Urdahl, A. M.; Wick, R. R.; Lohr, I. H.; Holt, K. E.
10.1101/2024.09.11.612360 — microbiology — Posted on 2024-09-11
3707 Aminolipid biosynthesis in response to phosphate limitation promotes colistin tolerance in Acinetobacter baumannii
Olea-Ozuna, R. J.; Campbell, M. J.; Quintanilla, S. Y.; Nandy, S.; Brodbelt, J. S.; Boll, J. M.
10.1101/2024.09.11.612458 — microbiology — Posted on 2024-09-11
3708 Exploiting the Achilles' Heel of Viral RNA Processing to Develop Novel Antivirals
Zahedi Amiri, A.; Ahmed, C.; Dahal, S.; Grosso, F.; Leng, H.; Stoilov, P.; Mangos, M.; Toutant, J.; Shkreta, L.; Attisano, L.; Chabot, B.; Brown, M.; Cochrane, A.
10.1101/2024.09.11.612277 — microbiology — Posted on 2024-09-11
3709 Effects of parental care on skin microbial community composition in poison frogs
Fischer, M.-T.; Xue, K. S.; Costello, E. K.; Dvorak, M.; Robaczewska, A.; Raboisson, G.; Caty, S.; Relman, D. A.; O'Connell, L. A.
10.1101/2024.09.11.612488 — microbiology — Posted on 2024-09-11
3710 The histone methyltransferase DOT1B is dispensable for stage differentiation and macrophage infection in Leishmania mexicana
Eisenhuth, N.; Rauh, E. T.; Mitnacht, M.; Debus, A.; Butter, F.; Schleicher, U.; Pruzinova, K.; Volf, P.; Janzen, C. J.
10.1101/2024.09.11.612422 — microbiology — Posted on 2024-09-11
3711 Antimicrobial activity of iron-depriving pyoverdines against human opportunistic pathogens
Vollenweider, V.; Rehm, K.; Chepkirui, C.; Perez-Berlanga, M.; Polymenidou, M.; Piel, J.; Bigler, L.; Kuemmerli, R.
10.1101/2023.07.18.549568 — microbiology — Posted on 2024-09-11
3712 CRISPR editing of candidate host factors that impact influenza A virus infection
Kyawe, P. P.; Liu, P.; Jiang, Z.; Bradley, E. S.; Cicuto, T.; Trombly, M. I.; Silverman, N.; Fitzgerald, K.; McDougall, W. M.; Wang, J. P.
10.1101/2024.09.10.612185 — immunology — Posted on 2024-09-11
3713 Removal of developmentally regulated microexons has a minimal impact on larval zebrafish brain morphology and function
Calhoun, C. C. S.; Capps, M. E. S.; Muya, K.; Gannaway, W. C.; Martina, V.; Conklin, C. L.; Klein, M. C.; Webster, J. M.; Torija-Olson, E. G.; Thyme, S.
10.1101/2024.08.19.608697 — neuroscience — Posted on 2024-09-11
3716 Disrupted development of sensory systems and the cerebellum in a zebrafish ebf3a mutant
Dang, N. D. P.; Conklin, C. L.; Truong, T. Q.; Vivian, M. D.; Wang, J.; Thomas, H. R.; Parant, J. M.; Yeo, N. C.; Thyme, S. B.
10.1101/2024.09.10.612287 — neuroscience — Posted on 2024-09-11
3717 Increasing adult-born neurons protects mice from epilepsy.
Jain, S.; LaFrancois, J. J.; Gerencer, K.; Botterill, J. J.; Kennedy, M.; Criscuolo, C.; Scharfman, H.
10.1101/2023.07.08.548217 — neuroscience — Posted on 2024-09-11
3718 Syngap1 regulates the synaptic drive and membrane excitability of Parvalbumin-positive interneurons in mouse auditory cortex
Francavilla, R.; Chattopadhyaya, B.; Damo Kamda, J. L.; Jadhav, V.; Kourrich, S.; Michaud, J. L.; Di Cristo, G.
10.1101/2024.02.27.582362 — neuroscience — Posted on 2024-09-11
3719 Single Distal Mutation Enhances Activity of known PETases via Stabilisation of PET-binding
Fu, X.; Gracia i Carmona, O.; Abrusan, G.; Jiao, X.; Diaciuc, A.; Gautel, M.; Fraternali, F.; Zelezniak, A.
10.1101/2024.09.11.612432 — synthetic biology — Posted on 2024-09-11
3720 Glucocorticoid chrono-pharmacology unveils novel targets for the cardiomyocyte-specific GR-KLF15 axis in cardiac glucose metabolism
El Abdellaoui-Soussi, F.; Durumutla, H. B.; Latimer, H.; Prabakaran, A. D.; McFarland, K.; Miz, K.; Piczer, K.; Werbrich, C.; Jain, M. K.; Haldar, S. M.; Quattrocelli, M.
10.1101/2023.12.18.572210 — physiology — Posted on 2024-09-11
3721 Molecular recording of cellular protein kinase activity with chemical labeling
Sun, D.-e.; Ng, S. W.; Zheng, Y.; Xie, S.; Schwan, N.; Breuer, P.; Hoffmann, D. C.; Michel, J.; Azorin, D. D.; Boonekamp, K. E.; Winkler, F.; Wick, W.; Boutros, M.; Li, Y.; Johnsson, K.
10.1101/2024.09.11.611894 — biochemistry — Posted on 2024-09-11
3724 IGF1R is protective in pneumococcal pneumonia
Felten, M.; Teixeira Alves, L.-G.; Letsiou, E.; Alfaro Arnedo, E.; Pineiro-Hermida, S.; Lopez, I. P.; Dietert, K.; Broemmel, T. C.; Gruber, A. D.; Fatykhova, D.; Hocke, A. C.; Lingscheid, T.; Lienau, J.; Rohde, G.; Capnetz Study Group, ; Pichel, J. G.; Witzenrath, M.
10.1101/2024.09.11.612370 — molecular biology — Posted on 2024-09-11
3725 SusC/D-like proteins in Gammaproteobacteria that utilize fructans
Zuehlke, M.-K.; Bahr, A.; Bartosik, D.; Solanki, V.; Teune, M.; Unfried, F.; Barbeyron, T.; Ficko-Blean, E.; Cladiere, L.; Jeudy, A.; Susemihl, A.; Hartmann, F.; Jouanneau, D.; Jam, M.; Hoehne, M.; Delcea, M.; Bornscheuer, U.; Becher, D.; Hehemann, J.-H.; Czjzek, M.; Schweder, T.
10.1101/2024.09.11.612387 — molecular biology — Posted on 2024-09-11
3728 Identification of Proteins Influencing CRISPR-Associated Transposases for Enhanced Genome Editing
Song, L.; Alker, A. T. P.; Oromi-Bosch, A.; Swartz, S. E.; Martinson, J. N. V.; Arora, J.; Wang, A. M.; Rovinsky, R.; Smith, S. J.; Pierce, E. C.; Deutschbauer, A. M.; Doudna, J. A.; Cress, B. F.; Rubin, B. E.
10.1101/2024.09.11.612086 — microbiology — Posted on 2024-09-11
3729 A high-throughput, microplate reader-based method to monitor in vitro HIV latency reversal in the absence of flow cytometry
Nkwelle, C. E.; Stephens, U.; Liang, K.; Cassel, J.; Salvino, J.; Montaner, L. J.; Ndip, R. N.; Esemu, S. N.; Ntie-Kang, F.; Tietjen, I.
10.1101/2024.09.11.612557 — microbiology — Posted on 2024-09-11
3731 Single-stranded HDR templates with truncated Cas12a binding sequences improve knock-in efficiencies in primary human T cells
Nitulescu, A.-M.; Du, W.; Glaser, V.; Kath, J.; Greensmith, R.; Mikkelsen, N. S.; Stein, M.; Bak, R.; Kaminski, M.; Wagner, D. L.
10.1101/2024.09.11.608426 — immunology — Posted on 2024-09-11
3732 Autophagy across tissues of aging mice
Carosi, J. M.; Martin, A.; Hein, L. K.; Hassiotis, S.; Hattersley, K. J.; Fourrier, C.; Bensalem, J.; Sargeant, T. J.
10.1101/2024.09.11.612427 — cell biology — Posted on 2024-09-11
3735 Hematopoietic Tet2 inactivation enhances the response to checkpoint blockade immunotherapy
Vanner, R. J.; Bansal, S.; Buttigeig, M. M.; Zeng, A. G. X.; Rondeau, V.; Chan, D. Y.; Chan-Seng-Yue, M.; Jin, L.; McLeod, J.; Donato, E.; Stelmach, P.; Vlasschaert, C.; Yang, Y.; Gupta, A.; Genta, S.; Sanz Garcia, E.; Shlush, L.; Ribeiro, M.; Butler, M. O.; Abelson, S.; Minden, M.; Chan, S. M.; Rauh, M. J.; Trumpp, A.; Dick, J. E.
10.1101/2024.09.09.612140 — cancer biology — Posted on 2024-09-11
3736 A proteome-wide dependency map of protein interaction motifs
Ambjoern, S.; Meeusen, B.; Kliche, J.; Wang, J.; Garvanska, D.; Kruse, T.; Lopez-Mendez, B.; Mann, M.; Mailand, N.; Hertz, E.; Davey, N. E.; Nilsson, J.
10.1101/2024.09.11.612445 — cell biology — Posted on 2024-09-11
3737 Optimized expansion microscopy reveals species-specific spindle microtubule organization in Xenopus egg extracts
Guilloux, G.; Kitaoka, M.; Mocaer, K.; Heichette, C.; Duchesne, L.; Heald, R.; Pecot, T.; Gibeaux, R.
10.1101/2024.09.11.612005 — cell biology — Posted on 2024-09-11
3738 Single molecule Lipid Biosensors Mitigate Inhibition of Endogenous Effector Proteins
Holmes, V.; Ricci, M. M. C.; Weckerly, C. C.; Worcester, M.; Hammond, G. R.
10.1101/2024.09.11.612480 — cell biology — Posted on 2024-09-11
3739 The DC1 domain protein Vacuoleless Gametophytes regulates stamen development in Arabidopsis
Amigo, N. L.; Arias, L. A.; Marchetti, M. F.; D'Ippolito, S.; Cascallares, M.; Lorenzani, S.; Frik, J.; Lombardo, M. C.; Terrile, M. C.; Casalongue, C. A.; Pagnussat, G. C.; Fiol, D. F.
10.1101/2024.02.19.580957 — plant biology — Posted on 2024-09-11
3740 In Vivo Optical Clearing of Mammalian Brain
Talei Franzesi, G.; Gupta, I.; Hu, M.; Piatkveich, K.; Yildirim, M.; Zhao, J.-P.; Eom, M.; Han, S.; Park, D.; Andaraarachchi, H.; Li, Z.; Greenhagen, J.; Islam, A. M.; Vashishtha, P.; Yaqoob, Z.; Pak, N.; Wissner-Gross, A. D.; Martin-Alarcon, D.; Veinot, J.; So, P. T.; Kortshagen, U.; Yoon, Y.-G.; Sur, M.; Boyden, E. S.
10.1101/2024.09.05.611421 — bioengineering — Posted on 2024-09-11
3741 Substrate stiffness regulates neuronal maturation via Piezo1-mediated TTR activity
Kreysing, E.; Gautier, H.; Humphrey, R. J.; Mooslehner, K. A.; Muresan, L. A.; Haarhoff, D.; Mukherjee, S.; Zhao, X. X.; Winkel, A. K.; Dimitracopoulos, A.; Pillai, E. K.; Karadottir, R. T.; Franze, K.
10.1101/2024.07.25.605128 — developmental biology — Posted on 2024-09-11
3742 A STING-CASM-GABARAP Pathway Activates LRRK2 at Lysosomes
Bentley-DeSousa, A.; Roczniak-Ferguson, A.; Ferguson, S. M.
10.1101/2023.10.31.564602 — cell biology — Posted on 2024-09-11
3746 A transcription factor quintet orchestrating bundle sheath expression in rice
Hua, L.; Wang, N.; Stanley, S.; Donald, R.; Kumar Eeda, S.; Billakurthi, K.; Borba, A. R.; Hibberd, J. M.
10.1101/2024.06.17.599020 — plant biology — Posted on 2024-09-11
3750 Brain-wide projections of mouse dopaminergic zona incerta neurons
Bono, B. S.; Negishi, K.; Dumiaty, Y.; Ponce, M. S.; Akinbode, T. C.; Baker, K. S.; Spencer, C. D. P.; Mejia, E.; Guirguis, M.; Hebert, A. J.; Khan, A. M.; Chee, M. J.
10.1101/2024.09.06.611701 — neuroscience — Posted on 2024-09-11
3751 Improving anxiety research: novel approach to reveal trait anxiety through summary measures of multiple states
Varga, Z. K.; Pejtsik, D.; Toth, M.; Balogh, Z.; Aliczki, M.; Szente, L.; Balla, G. Y.; Kontra, L.; Eckert, Z.; Zsolt, B.; Mikics, E.
10.1101/2023.06.01.543235 — neuroscience — Posted on 2024-09-11
3752 A near-tight lower bound on the density of forward sampling schemes
Kille, B.; Groot Koerkamp, R.; McAdams, D.; Liu, A.; Treangen, T.
10.1101/2024.09.06.611668 — bioinformatics — Posted on 2024-09-11
3753 Simulating CD8 T Cell Exhaustion: A Comprehensive Approach
Manrique-Rincon, A. J.; Foster, B.; Horswell, S.; Goulding, D. A.; Adams, D. J.; Speak, A. O.
10.1101/2024.09.06.611697 — immunology — Posted on 2024-09-11
3755 Death in the taste bud: Morphological features of dying taste cells and engulfment by Type I cells
Wilson, C. E.; Lasher, R. S.; Salcedo, E.; Yang, R.; Dzowo, Y.; Kinnamon, J. C.; Finger, T. E.
10.1101/2024.09.06.611711 — neuroscience — Posted on 2024-09-11
3756 Discovery of a new species of subterranean eel loach from southern India
RAMANATHAN, S. K.; B, P.; Raju, A. K.; Sukumaran, S.; Sebastian, W.; Anto, A.
10.1101/2024.09.10.612189 — zoology — Posted on 2024-09-11
3759 A bioengineered model of human placental exposure to environmental metals during pregnancy
Fattahi, P.; Younesi, M.; Lee, W. D.; Whang, K.; Kang, T.; Rabinowitz, J. D.; Aleksunes, L. M.; Huh, D. D.
10.1101/2024.09.06.611636 — bioengineering — Posted on 2024-09-11
3761 Microbiota drives the sexually dimorphic infection outcomes in mealworm beetles
Seal, S.; Kumar, D.; Thunga, P.; Khangar, P.; Gupta, M.; Basu, D. N.; Raychoudhury, R.; Khan, I.
10.1101/2024.09.10.611485 — evolutionary biology — Posted on 2024-09-11
3766 Early NK-cell and T-cell dysfunction marks progression to severe dengue in patients with obesity and healthy weight
Gregorova, M.; Santopaolo, M.; Garner, L. C.; Diamond, D.; Ramamurthy, N.; Tran, V.; Nguyen Minh, N.; Jones, E.; Nsubuga, M.; Luscombe, C.; Vo Thi My, H.; Quang Chanh, H.; Thi Xuan Chau, N.; Thi Hoai Tam, D.; Huynh Thi Le, D.; Thi Tam, C.; Klenerman, P.; Yacoub, S.; Rivino, L.
10.1101/2024.09.06.611687 — immunology — Posted on 2024-09-11
3767 Potent and selective repression of SCN9A by engineered zinc finger repressors for the treatment of neuropathic pain
samie, m.; Parman, T.; Jalan, M.; Lee, J.; Dunn, P.; Eshleman, J.; Baldwin Vidales, D.; Holter, J.; Jones, B.; Pan, Y.; Falaleeva, M.; Hinkley, S.; Goodwin, A.; Chen, T.; Bhardwaj, S.; Ward, A.; Trias, M.; Chikere, A.; Som, M.; Lu, Y.; Yadav, S.; Meyer, K.; Zeitler, B.; Fontenot, J.; Pooler, A.
10.1101/2024.09.06.609976 — neuroscience — Posted on 2024-09-11
3768 Variation in moment-to-moment brain state engagement changes across development and contributes to individual differences in executive function
Ye, J.; Tejavibulya, L.; Dai, W.; Cope, L. M.; Hardee, J. E.; Heitzeg, M. M.; Lichenstein, S.; Yip, S. W.; Banaschewski, T.; Baker, G. J.; Bokde, A. L. W.; Brühl, R.; Desrivieres, S.; Flor, H.; Gowland, P.; Grigis, A.; Heinz, A.; Martinot, J.-L.; Martinot, M.-L. P.; Artiges, E.; Nees, F.; Orfanos, D. P.; Poustka, L.; Hohmann, S.; Holz, N.; Baeuchl, C.; Smolka, M. N.; Vaidya, N.; Walter, H.; Whelan, R.; Schumann, G.; Garavan, H.; Chaarani, B.; Gee, D. G.; Baskin-Sommers, A.; Casey, B.; IMAGEN consortium, ; Scheinost, D.
10.1101/2024.09.06.611627 — neuroscience — Posted on 2024-09-11
3772 Neural Correlates of the Embodied Sense of Agency
Regev Krugwasser, A.; van der Goot, R.; Markusfeld, G.; Zvilichovsky, Y.; Salomon, R.
10.1101/2024.09.06.611665 — neuroscience — Posted on 2024-09-11
3775 Targeting CXCR4 with -Pentixather Significantly Increases Overall Survival in Small Cell Lung Cancer
Christensen, K. A.; Fath, M. A.; Ewald, J. T.; Robles-Planells, C.; Graves, S. A.; Johnson, S. S.; Zacharias, Z. R.; Houtman, J. C. D.; O'Dorisio, M. S.; Schultz, M. K.; Allen, B. G.; Furqan, M.; Menda, Y.; Liu, D.; Spitz, D. R.
10.1101/2024.09.06.611663 — cancer biology — Posted on 2024-09-11
3776 M3NetFlow: A novel multi-scale multi-hop graph AI model for integrative multi-omic data analysis
Zhang, H.; Goedegebuure, P.; Ding, L.; Hawkins, W.; DeNardo, D.; Fields, R.; Chen, Y.; Li, F.
10.1101/2023.06.15.545130 — bioinformatics — Posted on 2024-09-11
3778 Bioengineering Fascicle-like Skeletal Muscle Bioactuators via Pluronic-Assisted Co-axial 3D Bioprinting
Fuentes, J.; Mestre, R.; Guix, M.; Ghailan, I.; Ruiz-Gonzalez, N.; Patino, T.; Sanchez, S.
10.1101/2024.09.06.611597 — bioengineering — Posted on 2024-09-11
3782 Waves of light at the bottom of the ocean: insights into the luminous systems of three sea pens (Pennatuloidea, Octocorallia, Anthozoa)
Duchatelet, L.; Galeazzo, G. A.; Coubris, C.; Bridoux, L.; Rezsohazy, R.; Melo, M. R. S.; Marek, M.; Amaral, D. T.; Dupont, S.; Oliveira, A. G.; Delroisse, J.
10.1101/2024.04.30.591678 — zoology — Posted on 2024-09-11
3783 Haplotype-resolved genome and population genomics of the threatened garden dormouse in Europe
Byerly, P.; von Thaden, A.; Leushkin, E.; Hilgers, L.; Liu, S.; Winter, S.; Schell, T.; Buechner, S.; Meinig, H.; Lang, J.; Famira-Parcsetich, E.; Stubbe, S.; Gerheim, C.; Ben-Hamadou, A.; Bolz, H.; Betz, C.; Greve, C.; Mouton, A.; Bertolino, S.; Verbeylen, G.; Briner, T.; Vinciguerra, L.; Mueller, S.; Nowack, C.; Hiller, M.
10.1101/2024.02.21.581346 — genomics — Posted on 2024-09-11
3784 Saccadic omission revisited: What saccade-induced smear looks like
Schweitzer, R.; Doering, M. S.; Seel, T.; Raisch, J.; Rolfs, M.
10.1101/2023.03.15.532538 — neuroscience — Posted on 2024-09-11
3785 Nicotinamide riboside: A promising therapy for MI-induced acute kidney injury by upregulating nicotinamide phosphoribosyltransferase-mediated NAD levels
HABEICHI, N. J.; Amin, G.; Boitard, S. E.; Tannous, C. J.; Ghali, R.; MOMKEN, I.; Diab, R.; Booz, G. W.; Mericskay, M.; Zouein, F. A.
10.1101/2024.09.05.611567 — pharmacology and toxicology — Posted on 2024-09-11
3786 Spatial and Single Cell Mapping of Castleman Disease Reveals Key Stromal Cell Types and Cytokine Pathways
Smith, D.; Eichinger, A.; Rech, A.; Wang, J.; Esteva, E.; Seyedian, A.; Yang, X.; Zhang, M.; Martinez, D.; Tan, K.; Luo, M.; Park, C.; Reizis, B.; Pillai, V.
10.1101/2024.09.09.609717 — pathology — Posted on 2024-09-11
3787 Mitochondrial genomic alterations in cholangiocarcinoma cell lines
Faipan, A.; Sitthirak, S.; Wangwiwatsin, A.; Namwat, N.; Klanrit, P.; Titapan, A.; Jareanrat, A.; Thanasukarn, V.; Khuntikeo, N.; Boulter, L.; Loilome, W.
10.1101/2024.09.09.611963 — cancer biology — Posted on 2024-09-11
3790 Natural weed seed predators reduce crop yield loss due to weeds by 20% in cereal fields
Muneret, L.; Carbonne, B.; Chauvel, B.; Dosset, A.; Ducourtieux, C.; Henon, N.; Felten, E.; Laurent, E.; Matejicek, A.; Petit, S.
10.1101/2024.09.05.611395 — ecology — Posted on 2024-09-11
3791 Desmoplakin mutations in cardiac fibroblasts cause TGF?1-mediated pathological fibrogenesis in desmoplakin cardiomyopathy via beclin-1 regulation
Chen, H. V.; Wei, C.; Chan, S. F.; Saguner, A. M.; Brunckhorst, C. B.; Duru, F.; Marine, J. E.; James, C. A.; Calkins, H.; Judge, D.; Shou, W.
10.1101/2024.09.09.612149 — cell biology — Posted on 2024-09-11
3794 Enzymatic Degrading Chlorophenol Wastewater by Mixed Strains of Immobilized White Rot Fungi
Liu, H.; Lou, X.; Shao, Y.; Wang, Z.; Xiao, J.; Cen, K.; Chen, D.; Xia, Q.; Xu, W.; Fang, F.; Orooji, Y.; Liu, P.
10.1101/2024.09.09.611973 — microbiology — Posted on 2024-09-11
3796 Rapid intracellular acidification is a novel plant defense response countered by the brown planthopper
Jiang, Y.; Zhang, X.-Y.; Li, S.; Xie, Y.-C.; Yang, Y.; Pu, Z.; Zhang, L.; Lu, J.-B.; Huang, H.-J.; Zhang, C.-X.; He, S. Y.
10.1101/2023.05.24.542203 — plant biology — Posted on 2024-09-11
3798 SaprotHub: Making Protein Modeling Accessible to All Biologists
Su, J.; Li, Z.; Han, C.; Zhou, Y.; He, Y.; Shan, J.; Zhou, X.; Chang, X.; Ma, D.; OPMC, T.; Steinegger, M.; Ovchinnikov, S.; Yuan, F.
10.1101/2024.05.24.595648 — bioinformatics — Posted on 2024-09-11
3799 Enhancing the Reverse Transcriptase Function in Taq Polymerase via AI-driven Multiparametric Rational Design
Tomilova, Y. E.; Russkikh, N. E.; Yi, I. M.; Shaburova, E. V.; Tomilov, V. N.; Pyrinova, G. B.; Brezhneva, S. O.; Tikhonyuk, O. S.; Gololobova, N. S.; Popichenko, D. V.; Arkhipov, M. O.; Bryzgalov, L. O.; Brenner, E. V.; Artyukh, A. A.; Shtokalo, D. N.; Antonets, D. V.; Ivanov, M. K.
10.1101/2024.07.24.604875 — bioengineering — Posted on 2024-09-11
3801 Fusion, fission, and scrambling of the bilaterian genome in Bryozoa
Lewin, T. D.; Liao, I. J.-Y.; Chen, M.-E.; Bishop, J. D. D.; Holland, P. W. H.; Luo, Y.-J.
10.1101/2024.02.15.580425 — evolutionary biology — Posted on 2024-09-11
3802 Grains, trade and war in the multimodal transmission of Rice yellow mottle virus: an historical and phylogeographical retrospective
Ndikumana, I.; Onaga, G.; Pinel-Galzi, A.; Rocu, P.; Hubert, J.; Were, H. K.; Adego, A.; Were, M. N.; Poulicard, N.; Hebrard, M.; Dellicour, S.; Lemey, P.; Gilbert, E.; Dugue, M.-J.; Chevenet, F.; Bastide, P.; Guindon, S.; Fargette, D.; Hebrard, E.
10.1101/2024.08.20.608750 — evolutionary biology — Posted on 2024-09-11
3806 The fission yeast SUMO-targeted Ubiquitin Ligase Slx8 functionally associates with clustered centromeres and the silent mating type region at the nuclear periphery
Chakraborty, S.; Strachan, J.; Schirmeisen, K.; Besse, L.; Mercier, E.; Freon, K.; Zhang, H.; Zhao, N.; Bayne, E.; lambert, s. A.
10.1101/2024.09.10.612319 — cell biology — Posted on 2024-09-11
3808 Measuring the neurodevelopmental trajectory of excitatory-inhibitory balance via visual gamma oscillations
Rhodes, N.; Rier, L.; Singh, K. D.; Sato, J.; Vandewouw, M. M.; Holmes, N.; Boto, E.; Hill, R. M.; Rea, M.; Taylor, M.; Brookes, M. J.
10.1101/2024.09.10.612351 — neuroscience — Posted on 2024-09-11
3810 EHZ2 inhibition enhances the activity of platinum chemotherapy in aggressive variant prostate cancer
Latarani, M.; Pucci, P.; Eccleston, M.; Manzo, M.; Gangadharannambiar, P.; Alborelli, I.; Mongiardini, V.; Mahmood, N.; Colombo, M. P.; Grimaldi, B.; Rigas, S.; Akamatsu, S.; Hawkes, C.; Wang, Y.; Jachetti, E.; Crea, F.
10.1101/2024.09.06.611612 — pharmacology and toxicology — Posted on 2024-09-11
3813 High-coverage, massively parallel sequencing of single-cell genomes with CAP-seq
Li, M.; Zhai, X.; Li, J.; Li, S.; Du, Y.; Zhang, J.; Zhang, R.; Luo, Y.; Wei, W.; Liu, Y.
10.1101/2024.09.10.612220 — genomics — Posted on 2024-09-11
3815 Anti-phase clustering of regulatory factors shapes gene bursting
Li, B.; Wong, Y. Y.; Flores-Rodriguez, N.; Davidson, T.; Graus, M. S.; Smialkovska, V.; Ohishi, H.; Feldmann, A.; Ochiai, H.; Francois, M.
10.1101/2024.09.10.612363 — molecular biology — Posted on 2024-09-11
3817 Aversion encoding and behavioral state modulation of lateral habenula neurons
Zouridis, I. S.; Schmors, L.; Lecca, S.; Congiu, M.; Mameli, M.; Berens, P.; Burgalossi, A.
10.1101/2024.09.09.612004 — neuroscience — Posted on 2024-09-11
3818 Multi-epitope immunocapture of huntingtin reveals striatum-selective molecular signatures
Justice, J. L.; Greco, T. M.; Hutton, J. E.; Reed, T. J.; Mair, M. L.; Botas, J.; Cristea, I. M.
10.1101/2024.09.07.611843 — neuroscience — Posted on 2024-09-11
3820 Shox2 is necessary for normal thalamic spindle function
Febbo, I. G.; Maroteaux, M.; Yu, D.; Warkins, V.; Martinez, L. A.; Anderson, A. E.; Galazo, M. J.; Schrader, L. A.
10.1101/2024.09.10.612202 — neuroscience — Posted on 2024-09-11
3821 Effects Of Extrinsic Reward Based Skill Learning On Motor Plasticity
Yadav, G.; Vassiliadis, P.; Dubuc, C.; Hummel, F. C.; Derosiere, G.; Duque, J.
10.1101/2024.09.10.612238 — neuroscience — Posted on 2024-09-11
3822 Eye Movements in Silent Visual Speech track Unheard Acoustic Signals and Relate to Hearing Experience
Benz, K.; Hauswald, A.; Suess, N.; Gehmacher, Q.; Demarchi, G.; Schmidt, F.; Herzog, G.; Roesch, S.; Weisz, N.
10.1101/2024.09.10.610824 — neuroscience — Posted on 2024-09-11
3823 Early Life Neuroimaging: The Generalizability of Cortical Area Parcellations Across Development
Tu, J.; Myers, M.; Li, W.; Li, J.; Wang, X.; Dierker, D.; Day, T.; Snyder, A. Z.; Latham, A.; Kenley, J. K.; Sobolewski, C. M.; Wang, Y.; Labonte, A. K.; Feczko, E.; Kardan, O.; Moore, L. A.; Sylvester, C. M.; Fair, D. A.; Elison, J. T.; Warner, B. B.; Barch, D. M.; Rogers, C. E.; Luby, J. L.; Smyser, C. D.; Gordon, E. M.; Laumann, T. O.; Eggebrecht, A. T.; Wheelock, M. D.
10.1101/2024.09.09.612056 — neuroscience — Posted on 2024-09-11
3824 Omission-responsive neurons encode negative prediction error and probability in the auditory cortex
Yaron, A.; Shiramatsu-Isoguchi, T.; Kern, F. B.; Ohki, K.; Takahashi, H.; Chao, Z. C.
10.1101/2024.09.09.612166 — neuroscience — Posted on 2024-09-11
3826 Disrupted development of sensory systems and the cerebellum in a zebrafish ebf3a mutant
Dang, N. D. P.; Conklin, C. L.; Truong, T. Q.; Vivian, M. D.; Wang, J.; Thomas, H. R.; Parant, J. M.; Yeo, N. C.; Thyme, S.
10.1101/2024.09.10.612287 — neuroscience — Posted on 2024-09-11
3828 High early lactational synchrony within baboon groups predicts increased infant mortality
Winans, J. C.; Learn, N. H.; Siodi, I. L.; Warutere, J. K.; Archie, E. A.; Tung, J.; Alberts, S. C.; Markham, A. C.
10.1101/2024.09.09.611196 — animal behavior and cognition — Posted on 2024-09-11
3829 Single cell genome and epigenome co-profiling reveals hardwiring and plasticity in breast cancer
Wang, K.; Yan, Y.; Elgamal, H.; Li, J.; Tang, C.; Bai, S.; Xiao, Z.; Sei, E.; Lin, Y.; Wang, J.; Montalvan, J.; Nagi, C.; Thompson, A.; Navin, N.
10.1101/2024.09.06.611519 — genomics — Posted on 2024-09-10
3831 Generating human parvalbumin interneurons through 3D glia reprogramming
Stamouli, C. A.; Degener, A.; Cepeda-Prado, E.; Bruzelius, A.; Andersson, E.; Giacomoni, J.; Vorgeat, A. D.; Kidnapillai, S.; Klementieva, O.; Parmar, M.; Olariu, V.; Rylander Ottosson, D.
10.1101/2024.09.06.609855 — neuroscience — Posted on 2024-09-10
3834 The Greenland shark (Somniosus microcephalus) genome provides insights into extremelongevity
Sahm, A.; Cherkasov, A.; Liu, H.; Voronov, D.; Siniuk, K.; Schwarz, R.; Ohlenschlaeger, O.; Foerste, S.; Bens, M.; Groth, M.; Goerlich, I.; Paturej, S.; Klages, S.; Braendl, B.; Olsen, J.; Bushnell, P.; Poulsen, A. B.; Ferrando, S.; Garibaldi, F.; Drago, D. L.; Tozzini, E. T.; Mueller, F.-J.; Fischer, M.; Kretzmer, H.; Domenici, P.; Steffensen, J. F.; Cellerino, A.; Hoffmann, S.
10.1101/2024.09.09.611499 — genomics — Posted on 2024-09-10
3835 Herbivore prevalence poorly predicts yield in diverse cropping systems
Croijmans, L.; Mertens, D.; van Apeldoorn, D. F.; Jia, Y.; Rios Hernandez, N.; Poelman, E. H.
10.1101/2024.09.06.611601 — ecology — Posted on 2024-09-10
3836 Progress in Developing a Bark Beetle Identification Tool
Marais, G. C.; Stratton, I. C.; Hulcr, J.; Johnson, A. J.
10.1101/2024.09.08.611906 — ecology — Posted on 2024-09-10
3837 A can of worms: estimating the global number of earthworm species
Decaens, T.; Brown, G. G.; Cameron, E. K.; Csuzdi, C.; Eisenhauer, N.; Gerard, S.; Goulpeau, A.; Hedde, M.; James, S.; Lapied, E.; Maggia, M.-E.; Marchan, D. F.; Mathieu, J.; Phillips, H. R.; Marcon, E.
10.1101/2024.09.08.611896 — ecology — Posted on 2024-09-10
3838 Acute dietary methionine restriction highlights sensitivity of neocortex development to metabolic variations
Saha, S.; Debacq, C.; Audouard, C.; Jungas, T.; Dupre, P.; Fawal, M. A.; Chapat, C.; Michaud, H.-A.; Le Cam, L.; Lacroix, M.; Ohayon, D.; Davy, A.
10.1101/2024.09.10.612174 — developmental biology — Posted on 2024-09-10
3841 Hypoxia and loss of GCM1 expression prevents differentiation and contact inhibition in human trophoblast stem cells
Cinkornpumin, J. K.; Kwon, S. Y.; Prandstetter, A.-M.; Maxian, T.; Sirois, J.; Goldberg, J.; Zhang, J.; Saini, D.; Dasgupta, P.; Jeyarajah, M. J.; Renaud, S.; Paul, S.; Haider, S.; Pastor, W. A.
10.1101/2024.09.10.612343 — cell biology — Posted on 2024-09-10
3843 A cell and transcriptome atlas of the human arterial vasculature
Zhao, Q.; Pedroza, A.; Sharma, D.; Gu, W.; Dalal, A.; Weldy, C.; Jackson, W.; Li, D. Y.; Ryan, Y.; Nguyen, T.; Shad, R.; Palmisano, B. T.; Monteiro, J. P.; Worssam, M.; Berezwitz, A.; Iyer, M.; Shi, H.; Kundu, R.; Limbu, L.; Kim, J. B.; Kundaje, A.; Fischbein, M.; Wirka, R.; Quertermous, T.; Cheng, P.
10.1101/2024.09.10.612293 — cell biology — Posted on 2024-09-10
3845 Astrocyte ezrin defines resilience to stress-induced depressive behaviours in mice
Lin, S.-S.; Zhou, B.; Liu, S.-L.; Ren, X.-Y.; Guo, J.; Tong, J.-L.; Chen, B.-J.; Jiang, R.; Semyanov, A.; yi, c.; niu, j.; Illes, P.; Li, B.; tang, Y.; Verkhratsky, A.
10.1101/2024.09.10.612240 — neuroscience — Posted on 2024-09-10
3846 Ancient DNA Clarifies the Identity and Geographic Origin of the holotype of the genus Ctenomys
Maestri, R.; Goncalves, G. L.; Nicolas-Colin, V.; Bryjova, A.; Fornel, R.; Coissac, E.; Taberlet, P.; Moreira, G. R.; Ochotorena de Freitas, T. R.
10.1101/2024.09.10.612281 — zoology — Posted on 2024-09-10
3848 Andexanet alfa-associated heparin resistance in cardiac surgery: mechanism and in vitro perspectives
Chabata, C. V.; Yu, H.; Ke, L.; Frederiksen, J. W.; Patel, P. A.; Sullenger, B.; Thalji, N. K.
10.1101/2024.09.09.612152 — biochemistry — Posted on 2024-09-10
3849 Discovery of microsized RNA-derived RNAs and proteins in human cells
Huang, X.; Wu, H.; Zhong, W.; Li, W.; Liu, Z.; Zhao, M.; Xi, X.; Cao, B.; Pu, Y.; Kong, X.; Zhao, H.; Zhang, R.; Lai, K.; Lv, X.; Lv, Y.; Bao, J.; Wang, M.; Xiong, Y.; Dong, L.; Zhang, J.; Zhang, G.; Hu, Y.; Xu, J.; Chen, Y. E.; Chen, S.
10.1101/2023.04.24.538138 — biochemistry — Posted on 2024-09-10
3854 Actin dynamics switches two distinct modes of endosomal fusion in yolk sac visceral endoderm cells
Koike, S.; Tachikawa, M.; Tsutsumi, M.; Okada, T.; Nemoto, T.; Keino-Masu, K.; Masu, M.
10.1101/2023.12.17.572077 — cell biology — Posted on 2024-09-10
3856 Eukaryotic initiation factors eIF4F and eIF4B promote translation termination upon closed-loop formation
Shuvalova, E.; Shuvalov, A.; Sheikh, W. A.; Ivanov, A. V.; Biziaev, N.; Egorova, T. V.; Dmitriev, S. E.; Terenin, I. M.; Alkalaeva, E.
10.1101/2024.09.10.612082 — molecular biology — Posted on 2024-09-10
3857 Smooth muscle Cxcl12 activation is associated with vascular remodeling in flow-induced pulmonary hypertension
Klouda, T.; Tsikis, S. T.; Hirsch, T. I.; Kim, Y.; Liu, T.; Friehs, I.; Shyy, J. Y.- J.; Visner, G.; Raby, B. A.; Puder, M.; Yuan, K.
10.1101/2024.09.10.611870 — molecular biology — Posted on 2024-09-10
3858 A Comprehensive Atlas of AAV Tropism in the Mouse
Walkey, C. J.; Snow, K. J.; Bulcha, J.; Cox, A. R.; Martinez, A. E.; Ljungberg, M. C.; Lanza, D. G.; Giorgi, M. D.; Chuecos, M. A.; Alves-Bezerra, M.; Suarez, C. F.; Hartig, S. M.; Hilsenbeck, S. G.; Hsu, C.-W.; Saville, E.; Gaitan, Y.; Duryea, J.; Hannigan, S.; Dickinson, M. E.; Mirochnitchenko, O.; Wang, D.; Lutz, C. M.; Heaney, J. D.; Gao, G.; Murray, S. A.; Lagor, W. R.
10.1101/2024.09.10.612279 — molecular biology — Posted on 2024-09-10
3862 Human CCR4-NOT is a global regulator of gene expression and is a novel silencer of retrotransposon activation
Kulkarni, S.; Morrissey, A.; Sebastian, A.; Keller, C. A.; Giardine, B.; Smith, C.; Akinniyi, O. T.; Arnaoutov, A.; Albert, I.; Mahony, S.; Reese, J. C.
10.1101/2024.09.10.612038 — molecular biology — Posted on 2024-09-10
3865 Antiviral Mechanisms and Preclinical Evaluation of Amantadine Analogs that Continue to Inhibit Influenza A Viruses with M2 S31N-Based Drug Resistance
Tietjen, I.; Kwan, D. C.; Petrich, A.; Zell, R.; Antoniadou, I. T.; Gavriilidou, A.; Tzitzoglaki, C.; Rallis, M.; Fedida, D.; Sureda, F. X.; Mestdagh, C.; Naesens, L. M.; Chiantia, S.; Johnson, F. B.; Kolocouris, A.
10.1101/2024.09.09.612141 — microbiology — Posted on 2024-09-10
3867 Exploring the Phaeosphere: characterizing the microbiomes of Phaeocystis antarctica colonies from the coastal Southern Ocean and laboratory culture
Brisbin, M. M.; Acord, M.; Davitt, R.; Bent, S.; Van Mooy, B. A. S.; Flaum, E.; Norlin, A.; Turner, J.; Krinos, A.; Alexander, H.; Saito, M.
10.1101/2024.09.10.612332 — microbiology — Posted on 2024-09-10
3871 The two-component system ArlRS is essential for wall teichoic acid glycoswitching in Staphylococcus aureus
Kuijk, M. M.; Tusveld, E.; Lehmann, E.; van Dalen, R.; Lasa, I.; Ingmer, H.; Pannekoek, Y.; van Sorge, N. M.
10.1101/2024.09.10.612275 — microbiology — Posted on 2024-09-10
3874 Spatial arrangement of the whiskers of harbor seals (Phoca vitulina) compared to whisker arrangements of mice (Mus musculus) and rats (Rattus norvegicus)
Graff, M. M.; Belli, H. M.; Wieskotten, S.; Bresee, C. S.; Krüger, Y.; Janssen, T. L.; Dehnhardt, G.; Hartmann, M. J. Z.
10.1101/2024.01.15.575743 — neuroscience — Posted on 2024-09-10
3876 A circular engineered sortase for interrogating histone H3 in chromatin
Whedon, S. D.; Lee, K.; Wang, Z. A.; Zahn, E.; Lu, C.; Abeywardana, M. Y.; Fairall, L.; Nam, E.; Dubois-Coyne, S.; De Ioannes, P.; Sheng, X.; Andrei, A.; Lundberg, E.; Jiang, J.; Armache, K.-J. D.; Zhao, Y.; Schwabe, J. W. R.; Wu, M.; Garcia, B.; Cole, P. A.
10.1101/2024.09.10.612318 — biochemistry — Posted on 2024-09-10
3878 ATP-dependent remodeling of chromatin condensates uncovers distinct mesoscale effects of two remodelers
Moore, C. M.; Kaur, U.; Wong, E.; Chio, U. S. M.; Zhou, Z.; Ostrowski, M.; Wu, K.; Irkliyenko, I.; Wang, S.; Ramani, V.; Narlikar, G.
10.1101/2024.09.10.611504 — biochemistry — Posted on 2024-09-10
3879 The transcription factor Traffic jam orchestrates the somatic piRNA pathway in Drosophila ovaries
Brasset, E.; Mehouas, S. M.; Martins, A.; Mirouse, V.; Gueguen, N.; Malterre, N. M.; Bertin, B.; Nicholson, B. C.; Alizada, A.; Hannon, G. J.; Suarez, J. R.; Lau, N. C.; Rivera, A. J.
10.1101/2024.09.10.612307 — molecular biology — Posted on 2024-09-10
3881 Efficient genome replication in influenza A virus requires NS2 and sequence beyond the canonical promoter
Swaminath, S.; Mendes, M.; Zhang, Y.; Remick, K. A.; Mejia, I.; Guereca, M.; te Velthuis, A. J. W.; Russell, A. B.
10.1101/2024.09.10.612348 — microbiology — Posted on 2024-09-10
3882 Small mammals in biodiversity hotspot harbor viruses of epidemic potential
Feng, Y.; Kuang, G.; Pan, Y.; Wang, J.; Yang, W.; Wu, W.-c.; Pan, H.; Wang, J.; Han, X.; Yang, L.; Xin, G.-y.; Shan, Y.-t.; Gou, Q.-y.; Liu, X.; Guo, D.; Liang, G.; Holmes, E. C.; Gao, Z.; Shi, M.
10.1101/2024.09.10.612213 — microbiology — Posted on 2024-09-10
3891 Investigation of hemodynamic bulk flow patterns caused by aortic stenosis using a combined 4D Flow MRI-CFD framework
Wang, T.; Quast, C.; Bönner, F.; Kelm, M.; Zeus, T.; Lemainque, T.; Steinseifer, U.; Neidlin, M.
10.1101/2024.09.09.611958 — bioengineering — Posted on 2024-09-10
3892 Glial Reactivity and Cognitive Decline Follow Chronic Heterochromatin Loss in Neurons
Newman, A. G.; Sharif, J.; Bessa, P.; Zaqout, S.; Brown, J.; Richter, D.; Dannenberg, R.; Nakayama, M.; Mueller, S.; Schaub, T.; Manickaraj, S.; Böhm-Sturm, P.; Ohara, O.; Koseki, H.; Singh, P. B.; Tarabykin, V.
10.1101/2022.08.29.505641 — neuroscience — Posted on 2024-09-10
3893 Riemannian Geometry for the Classification of Brain States with fNIRS
Näher, T.; Bastian, L.; Vorreuther, A.; Fries, P.; Goebel, R. W.; Sorger, B.
10.1101/2024.09.06.611347 — neuroscience — Posted on 2024-09-10
3895 The flexible stalk domain of sTREM2 modulates its interactions with phospholipids in the brain
Saeb, D.; Lietzke, E. E.; Fuchs, D. I.; Aldrich, E. C.; Bruce, K. D.; Sprenger, K. G.
10.1101/2024.09.04.611223 — bioengineering — Posted on 2024-09-10
3898 Extracellular vesicles regulate metastable phenotypes of lymphangioleiomyomatosis cells via shuttling ATP synthesis to pseudopodia and activation of integrin adhesion complexes.
Kalvala, A. K.; Silwal, A.; Patel, B.; Kasetti, A.; Shetty, K.; Cho, J.-H.; Lara, G.; Daugherity, B.; Diesler, R.; Pooladanda, V.; Rueda, B. R.; Henske, E. P.; Yu, J. J.; Markiewski, M. M.; Karbowniczek, M.
10.1101/2024.09.09.611297 — cancer biology — Posted on 2024-09-10
3899 Subtype-specific Patterns of Evolution and Clinically Relevant Genomic Instability in Wilms Tumour
Cresswell, G. D.; Chagtai, T.; Al-Saadi, R.; Treger, T. D.; Madhan, G.; Mifsud, B.; Vujanic, G.; Williams, R. D.; Luscombe, N. M.; Pritchard-Jones, K.; Mifsud, W.
10.1101/2024.09.04.610994 — cancer biology — Posted on 2024-09-10
3901 Resilience and vulnerability of neural speech tracking in children with cochlear implants
Federici, A.; Fantoni, M.; Pavani, F.; Handjaras, G.; Bednaya, E.; Martinelli, A.; Berto, M.; Ricciardi, E.; Nava, E.; Orzan, E.; Bianchi, B.; Bottari, D.
10.1101/2024.02.22.581545 — neuroscience — Posted on 2024-09-10
3902 Human birth tissue products as a non-opioid medicine to inhibit post-surgical pain
Zhang, C.; Huang, Q.; Ford, N. C.; Limjunyawong, N.; Lin, Q.; Yang, F.; Cui, X.; Uniyal, A.; Liu, J.; Mahabole, M.; He, H.; Wang, X.; Duff, I.; Wang, Y.; Wan, J.; Zhu, G.; Raja, S. N.; Jia, H.; Yang, D.; Dong, X.; Cao, X.; Tseng, S.; He, S.; Guan, Y.
10.1101/2024.05.19.594874 — neuroscience — Posted on 2024-09-10
3906 Endogenous viral elements constitute a complementary source of antigens for personalized cancer vaccines
Garde, C.; Pavlidis, M. A.; Garces, P.; Lange, E. J.; Ramarathinam, S. H.; Sokac, M.; Pandey, K.; Faridi, P.; Ahrenfeldt, J.; Chung, S.; Friis, S.; Kleine-Kohlbrecher, D.; Birkbak, N. J.; Kringelum, J. V.; Rono, B.; Purcell, A. W.; Trolle, T.
10.1101/2023.03.23.533908 — cancer biology — Posted on 2024-09-10
3910 Fibril Paint: a class of amyloid-targeting peptides
Pedrola, J. A.; Dekker, F. A.; Guttmann, K.; van Leeuwen, L. M.; Singh, S.; Mayer, G.; Garfagnini, T.; Friedler, A.; Rudiger, S. G. D.
10.1101/2024.08.25.609586 — biochemistry — Posted on 2024-09-10
3911 Uncovering Plaque-Glia Niches in Human Alzheimer's Disease Brains Using Spatial Transcriptomics
Avey, D. R.; Ng, B.; Vialle, R. A.; Kearns, N. A.; Lopes, K. d. P.; Iatrou, A.; Tissera, S. D.; Vyas, H.; Saunders, D. M.; Flood, D. J.; Xu, J.; Tasaki, S.; Gaiteri, C.; Bennett, D. A.; Wang, Y.
10.1101/2024.09.05.611566 — genomics — Posted on 2024-09-10
3917 Adipocyte-specific deletion of Dbc1 does not recapitulate healthy obesity phenotype but suggests regulation of inflammation signaling
Santos, L.; Fort, R. S.; Schlapp, G.; Cal, K.; Perez-Torrado, V.; Meikle, M. N.; Mulet, A. P.; Sotelo-Silveira, J.; Verdes, J. M.; Contreras, P.; Calliari, A. J.; Badano, J. L.; Crispo, M.; Escande, C.
10.1101/2024.09.08.611743 — physiology — Posted on 2024-09-10
3921 Cloud-enabled Scalable Analysis of Large Proteomics Cohorts
Guturu, H.; Nichols, A.; Cantrell, L. S.; Just, S.; Kis, J.; Platt, T.; Mohtashemi, I.; Wang, J.; Batzoglou, S.
10.1101/2024.09.05.611509 — bioinformatics — Posted on 2024-09-10
3922 The FAIR Data Point Populator: collaborative FAIRification and population of FAIR Data Points
Wijnbergen, D.; Kaliyaperumal, R.; Burger, K.; Bonino da Silva Santos, L. O.; Mons, B.; Roos, M.; Mina, E.
10.1101/2024.09.06.611505 — bioinformatics — Posted on 2024-09-10
3925 Feasibility of Measuring Magnetic Resonance Elastography-derived Stiffness in Human Thoracic Aorta and Aortic Dissection Phantoms
Hirad, A. A.; Fakhouri, F. S.; Raterman, B.; Lakony, R.; Wang, M.; Gonring, D.; Kedwai, B.; Kolipaka, A.; Mix, D. A.
10.1101/2024.09.05.611548 — bioengineering — Posted on 2024-09-10
3929 Understanding Ecological Systems Using Knowledge Graphs: An Application to Highly Pathogenic Avian Influenza
Robertson, H.; Han, B. A.; Castellanos, A. A.; Rosado, D.; Stott, G.; Zimmerman, R.; Drake, J. M.; Graeden, E.
10.1101/2024.09.05.611483 — ecology — Posted on 2024-09-10
3930 Autoantigen TRIM21 (Ro52) assembles pro-inflammatory immune complexes following lytic cell death
Jones, E. L.; Demarco, B.; de Jong, M. M.; Cai, H.; Hill, S.; Glass, R. E.; Harris, G.; Nayar, S.; Fisher, B. A.; Gerard, A.; Bezbradica, J. S.; Dustin, L. B.
10.1101/2024.09.06.611470 — immunology — Posted on 2024-09-10
3931 CD300f immune receptor is a microglial tissue damage sensor and regulates efferocytosis after brain damage
Negro-Demontel, M. L.; Evans, F.; Cawen, F. A.; Fitzpatrick, Z.; Mason, H. D.; Ali-Ruiz, D.; Peluffo, H.
10.1101/2024.09.06.611174 — neuroscience — Posted on 2024-09-10
3934 Imputed DNA methylation outperforms measured loci associations with smoking and chronological age
Richmond, A.; Mur, J.; Harris, S.; Corley, J.; Elliott, H. R.; Foley, C. N.; Hannon, E.; Kuncheva, Z.; Min, J.; Moqri, M.; Ndiaye, M.; Sun, B.; Vallejos, C.; Ying, K.; Gladyshev, V. N.; Cox, S. R.; McCartney, D. L.; Marioni, R.
10.1101/2024.09.05.611501 — genetics — Posted on 2024-09-10
3935 Repurposing the plant-derived compound apigenin for senomorphic effect in antiaging pipelines
Zhang, H.; Xu, Q.; Jiang, Z.; Sun, R.; Liu, S.; Kirkland, J. L.; Zhang, W.; Sun, Y.
10.1101/2024.09.09.611999 — cell biology — Posted on 2024-09-10
3936 Glia multitask to compensate for neighboring glial cell dysfunction
Beachum, A. N.; Salazar, G.; Nachbar, A.; Krause, K.; Klose, H.; Meyer, K.; Maserejian, A.; Ross, G.; Boyd, H.; Weigel, T.; Ambaye, L.; Miller, H.; Coutinho-Budd, J.
10.1101/2024.09.06.611719 — neuroscience — Posted on 2024-09-10
3938 Lessons learned during the journey of data: from experiment to model for predicting kinase affinity, selectivity, polypharmacology, and resistance
Lopez-Rios de Castro, R.; Rodriguez-Guerra, J.; Schaller, D.; Kimber, T. B.; Taylor, C.; White, J. B.; Backenkohler, M.; Payne, A.; Kaminow, B.; Pulido, I.; Singh, S.; Krammer, P. L.; Perez-Hernandez, G.; Volkamer, A.; Chodera, J. D.
10.1101/2024.09.10.612176 — biophysics — Posted on 2024-09-10
3939 A fluid droplet harvests the force generated by shrinking microtubules in living cells
Morelli, K.; Meier, S. M.; Zhao, A.; Choudhury, M.; Willis, M.; Barral, Y.; Vogel, J.
10.1101/2024.09.09.612121 — biophysics — Posted on 2024-09-10
3941 Branched-chain amino acid metabolism is a crucial modulator of cellular senescence
Aramaki, Y.; Irie, K.; Obinata, H.; Honda, S.; Horii, T.; Arakawa, S.; Tsuchida, A.; Hoshino, J.; Kobayashi, R.; Izumi, T.; Hatada, I.; Shimizu, S.; Minamishima, Y. A.; Konishi, A.
10.1101/2024.09.10.612139 — cell biology — Posted on 2024-09-10
3943 Characterization and Antiatherogenic Potential of P3R99 Monoclonal Antibody Against Sulfated Glycosaminoglycans: Physicochemical and Functional Insights
Valencia, L. M.; Martinez-Montano, Y.; Gomez, J. A.; Sarduy, R.; Hernandez, A.; Proctor, S. D.; Fernandez-Calienes, A.; Brito, V.; Soto, Y.
10.1101/2024.09.09.612153 — immunology — Posted on 2024-09-10
3944 Divergent response to radio-immunotherapy is defined by intrinsic features of the tumor microenvironment
Karam, S. D.; Gadwa, J.; Yu, J.; Piper, M.; Knitz, M. W.; Darragh, L. B.; Olimpo, N. A.; Corbo, S.; Neupert, B.; Beynor, J. I.; Nguyen, A.; Hodgson, C.; Abdelazeem, K. N. M.; Nguyen, D.; Saviola, A.; Pincha, M.; Klein, C.; Amann, M.
10.1101/2024.09.06.611679 — immunology — Posted on 2024-09-10
3945 Mapping the topographic organization of the human zona incerta using diffusion MRI
Haast, R. A.; Kai, J.; Taha, A.; Liu, V.; Gilmore, G.; Guye, M.; Khan, A. R.; Lau, J. C.
10.1101/2024.09.05.610266 — neuroscience — Posted on 2024-09-10
3946 Hyperglycemia selectively increases cerebral non-oxidative glucose consumption without affecting blood flow
Blazey, T.; Lee, J. J.; Snyder, A. Z.; Goyal, M. S.; Hershey, T.; Arbelaez, A. M.; Raichle, M. E.
10.1101/2024.09.05.611035 — neuroscience — Posted on 2024-09-10
3950 Drift in Individual Behavioral Phenotype as a Strategy for Unpredictable Worlds
Maloney, R. T.; Ye, A. Q.; Saint Pre, S.-K.; Alisch, T.; Zimmerman, D. M.; Pittoors, N. C.; de Bivort, B. L.
10.1101/2024.09.05.611301 — neuroscience — Posted on 2024-09-10
3951 Discovery of novel 1,4-dicarbonylthiosemicarbazides as DNA gyrase inhibitors for the treatment of MRSA infection
Zhang, G.; Liang, J.; Wen, G.; Yao, M.; Jia, Y.; Feng, B.; Li, J.; Han, Z.; Liu, Q.; Li, T.; Zhang, W.; Jin, H.; Xia, J.; Peng, L.; Wu, S.
10.1101/2024.09.05.611349 — pharmacology and toxicology — Posted on 2024-09-10
3953 NMR at operational temperature for resonance assignments of a PET degrading enzyme
Gabrielli, V.; Grga, J.; Gavalda, S.; Perrot, L.; Boll, E.; Lippens, G.; Charlier, C.; Lippens, G.
10.1101/2024.09.10.612188 — biophysics — Posted on 2024-09-10
3957 In cell NMR reveals cells selectively amplify and structurally remodel amyloid fibrils
Ansari, S.; Lagasca, D.; Dumarieh, R.; Xiao, Y.; Krishna, S.; Li, Y.; Frederick, K. K.
10.1101/2024.09.09.612142 — biophysics — Posted on 2024-09-10
3958 The structural influence of the oncogenic driver mutation N642H in the STAT5B SH2 domain
Haas-Neill, L.; Meneksedag-Erol, D.; Chaudhry, A.; Novoselova, M.; Ashraf, Q. F.; de Araujo, E. D.; Wilson, D. J.; Rauscher, S.
10.1101/2024.09.09.612134 — biophysics — Posted on 2024-09-10
3960 The molecular origin of body temperature in homeothermic species
Artmann, G. M.; Weiergraeber, O. H.; Damiati, S. A. M.; Firat, I. S.; Artmann, A.
10.1101/2024.09.10.612206 — biophysics — Posted on 2024-09-10
3963 Engineered chitosan-derived nanocarrier for efficient siRNA delivery to peripheral and central neurons
Spencer, A. P.; Vilaca, A.; Xavier, M.; Santos, R.; Ionescu, A.; Lazaro, M.; Leiro, V.; Perlson, E.; Guimaraes, S. C.; Maoz, B. M.; Pego, A. P.
10.1101/2024.09.05.611434 — bioengineering — Posted on 2024-09-10
3964 Unveiling the potential of neuron-targeted dendriplexes for siRNA delivery using a PNS-CNS-on-Chip
Spencer, A. P.; Xavier, M.; Guimaraes, S. C.; Vilaca, A.; Ionescu, A.; Santos, R.; Lazaro, M.; Perlson, E.; Leiro, V.; Maoz, B. M.; Pego, A. P.
10.1101/2024.09.05.611457 — bioengineering — Posted on 2024-09-10
3966 Targeted Polymersomes Enable Enhanced Delivery to Peripheral Nerves Post-Injury
Trumbull, K.; Fetten, S.; Montgomery, D.; Marahrens, V.; Myers, O.; Arnold, N.; Twiss, J. L.; Larsen, J.
10.1101/2024.09.05.611478 — bioengineering — Posted on 2024-09-10
3970 State of India's Birds 2023: A framework to leverage semi-structured citizen science for bird conservation
Viswanathan, A.; Thrikkadeeri, K.; Koulgi, P.; J, P.; Deomurari, A.; Jha, A.; Warudkar, A.; Suryawanshi, K.; Madhusudan, M.; Kaushik, M.; Goyal, N.; bangal, P.; Jayapal, R.; Quader, S.; Dutta, S.; Menon, T.; Ramachandran, V.
10.1101/2024.09.05.611348 — ecology — Posted on 2024-09-10
3976 β2-Adrenergic Biased Agonist Inhibits the Development of Th17 and the Response of Memory Th17 Cells in an NF-κB-Dependent Manner.
Hajiaghayi, M.; Gholizadeh, F.; Han, E.; Little, S.; Rahbari, N.; Ardila, I.; Naranjo, C. L.; Tehranimeh, K.; Shih, S. C.; Darlington, P. J.
10.1101/2024.09.08.611829 — immunology — Posted on 2024-09-10
3983 Time-on-task-related decrements in performance in the rodent continuous performance test are not caused by physical disengagement from the task
Li, Y.; van Kralingen, T.; Masi, M.; Villaneuva Sanchez, B.; Mitchell, B.; Johnson, J.; Miranda-Barrientos, J.; Rehg, J. J.; Martinowich, K.; Carr, G. V.
10.1101/2024.09.05.611415 — neuroscience — Posted on 2024-09-10
3986 Biomolecular condensation of ERC1 recruits ATG8 and NBR1 to drive autophagosome formation for plant heat tolerance
Chung, K. K.; Zhao, Z.; Law, K. C.; Ma, J.; Chiang, C. H. J.; Leung, K. H.; Shrestha, R.; Wu, Y.; Li, C.; Feng, L.; Li, X.; Lee, K.-M.; Wong, K.-B.; Xu, S.-L.; Gao, C.; Zhuang, X.
10.1101/2024.09.09.611939 — plant biology — Posted on 2024-09-10
3988 Lysyl Oxidases are Necessary for Myometrial Contractility and On-Time Parturition in Mice
Ouellette, A.; Do, C.; Cohn-Guthrie, S.; Lam, Y.-W.; Mahendroo, M.; Nallasamy, S.
10.1101/2024.09.05.610344 — physiology — Posted on 2024-09-10
3990 LYMTACs: Chimeric Small Molecules Repurpose Lysosomal Membrane Proteins for Target Protein Relocalization and Degradation
Nalawansha, D. A.; Mazis, G.; Husemoen, G.; Ashton, K. S.; Deng, W.; Wurz, R. P.; Tran, A. T.; Lanman, B. A.; Xie, J.; Guenette, R. G.; Li, S.; Smith, C. E.; Archunan, S.; Agnihotram, M. K.; Sadhukhan, A.; Kapoor, R.; Koirala, S.; De Sousa E Melo, F.; Potts, P. R.
10.1101/2024.09.08.611923 — cancer biology — Posted on 2024-09-10
3991 Automated measurement of cardiomyocyte monolayer contraction using the Exeter Multiscope
Corbett, A. D.; Horsell, D.; Watters, T.; Ghasemi, S.; Henderson, L.; Mohanan, S.; Mullenbroich, C.; Bub, G.; Burton, F.; Smith, G. L.
10.1101/2024.09.09.611998 — biophysics — Posted on 2024-09-10
3994 Structural insights into distinct mechanisms of RNA polymerase II and III recruitment to snRNA promoters
Shah, S. Z.; Perry, T. N.; Graziadei, A.; Cecatiello, V.; Kaliyappan, T.; Misiaszek, A. D.; Muller, C. W.; Ramsay, E. P.; Vannini, A.
10.1101/2024.09.10.612236 — biochemistry — Posted on 2024-09-10
3995 Controlled and polygynous mating in the black soldier fly: advancing breeding programs through quantitative genetic designs
Jensen, K.; Thormose, S. F.; Noer, N. K.; Schou, T. M.; Kargo, M.; Gligorescu, A.; Noergaard, J. V.; Hansen, L. S.; Zaalberg, R. M.; Nielsen, H. M.; Kristensen, T. N.
10.1101/2024.09.09.611978 — animal behavior and cognition — Posted on 2024-09-10
3997 Evolution of venom production in marine predatory snails
Zancolli, G.; Modica, M. V.; Puilladre, N.; Kantor, Y.; Barua, A.; Campli, G.; Robinson-Rechavi, M.
10.1101/2024.09.09.612013 — evolutionary biology — Posted on 2024-09-10
3999 The chromatin remodeler DEK promotes proliferation of mammary epithelium and is associated with H3K27me3 epigenetic modifications
Johnstone, M.; Leck, A.; Lange, T. E.; Wilcher, K. E.; Shephard, M. S.; Paranjpe, A.; Schutte, S.; Wells, S. I.; Kappes, F.; Salomonis, N.; Privette Vinnedge, L. M.
10.1101/2024.09.09.612116 — developmental biology — Posted on 2024-09-10
4000 Axolotl epigenetic clocks offer insights into the nature of negligible senescence
Haluza, Y.; Zoller, J. A.; Lu, A. T.; Walters, H. E.; Lachnit, M.; Lowe, R.; Haghani, A.; Brooke, R. T.; Park, N.; Yun, M. H.; Horvath, S.
10.1101/2024.09.09.611397 — developmental biology — Posted on 2024-09-10
4002 Characterisation of cell cycle checkpoint kinases in Toxoplasma gondii
Johnson, M. K.; Chelaghma, S.; Koreny, L.; Waller, R. F.; Merrick, C. J.
10.1101/2024.09.10.612042 — microbiology — Posted on 2024-09-10
4004 Distributional learning drives statistical deafening
Luthra, S.; Luor, A.; Tierney, A. T.; Dick, F.; Holt, L. L.
10.1101/2024.09.09.612146 — neuroscience — Posted on 2024-09-10
4005 Selenocysteine tRNA methylation promotes oxidative stress resistance in melanoma metastasis
Nease, L. A.; Church, K. P.; Delclaux, I.; Murakami, S.; Amiama, M. A.; Zerhouni, M.; Cascio, G.; Hughes, R. O.; Zumbo, P.; Dow, L. E.; Jaffrey, S. R.; Betel, D.; Piskounova, E.
10.1101/2023.10.02.560568 — cancer biology — Posted on 2024-09-10
4006 FGFR2 promotes resistance to ALK tyrosine kinase inhibitors and its inhibition acts synergistically with lorlatinib in the treatment of ALK-expressing neuroblastoma
Pucci, P.; Barrett, C.; Trigg, R.; Matthews, J. D.; Borenas, M.; Schlederer, M.; Jahangiri, L.; Hare, L.; Steel, C.; James, E.; Prokoph, N.; Kenner, L.; Palmer, R.; Hallberg, B.; Burke, A.; Turner, S. D.
10.1101/2024.09.05.611416 — cancer biology — Posted on 2024-09-10
4007 The Role of Cholesterol in M2 Clustering and Viral Budding Explained
Kolokouris, D.; Kalederoglou, I. E.; Duncan, A. L.; Corey, R. A.; Sansom, M.; Kolocouris, A.
10.1101/2024.09.09.611993 — biophysics — Posted on 2024-09-10
4008 De novo design of Ras isoform selective binders
Zhang, J. Z.; Li, X.; Liu, C.; Jiang, H.; Wu, K.; Baker, D.
10.1101/2024.08.29.610300 — bioengineering — Posted on 2024-09-10
4010 Preimplantation Embryos Amplify Stress-Induced Changes in Sperm-Derived miRNA Content to Mediate Transgenerational Epigenetic Inheritance
Champroux, A.; Yang, T.; Dickson, D. A.; Meng, A.; Harrington, A.; Liaw, L.; Marzi, M.; Nicassio, F.; Schlaeger, T.; Feig, L.
10.1101/2023.04.21.537854 — genetics — Posted on 2024-09-10
4012 The pathway to resolve dimeric forms distinguishes plasmids from megaplasmids in Enterobacteriaceae
Fournes, F.; Campos, M.; Cury, J.; Schiavon, C.; Pages, C.; Touchon, M.; Rocha, E. P. C.; Rousseau, P.; Cornet, F.
10.1101/2024.04.05.588136 — microbiology — Posted on 2024-09-10
4013 An emerging PB2-627 polymorphism increases the pandemic potential of avian influenza virus by breaking through ANP32 host restriction in mammalian and avian hosts
Guo, Y.; Shu, S.; Zhou, Y.; Peng, W.; Jiang, Z.; Li, Y.; Li, T.; Du, F.; Wang, L.; Chen, X.; Dong, J.; Zhao, C.; Wang, M. H.; Sun, Y.; Sun, H.; Lu, L.; Digard, P.; Chang, K.-c.; Yen, H.-L.; Liu, J.; Pu, J.
10.1101/2024.07.03.601996 — microbiology — Posted on 2024-09-10
4014 The bioreactor microbiome of mass cultivated marine diatoms for industrial carbon capture and utilization
Aalto, N. J.; Giaver, I. H.; Eriksen, G. K.; Israelsen, L.; Krsmanovic, S.; Petters, S.; Bernstein, H. C.
10.1101/2023.11.01.565100 — microbiology — Posted on 2024-09-10
4015 NK Cell Exhaustion in Wilson's Disease Revealed by Single-cell RNA Sequencing Predicts the Prognosis of Cholecystitis
Jin, Y.; Xing, J.; Dai, C.; Jin, L.; Zhang, W.; Tao, Q.; Hou, M.; Li, Z.; Yang, W.; Feng, Q.; Wang, H.; Yu, Q.
10.1101/2024.05.02.592210 — immunology — Posted on 2024-09-10
4016 CD200 depletion in glioma enhances antitumor immunity and induces tumor rejection
Raphael, I.; Mujeeb, A. A.; Ampudia-Mesias, E.; Sever, R. E.; McClellan, B.; Frederico, S. C.; Sneiderman, C. T.; Mirji, A.; Daba, A.; Puerta-Martinez, F.; Nisnboym, M.; Edwards, W. B.; Graner, M.; Moertel, C.; Castro, M. G.; Kohanbash, G.; Olin, M.
10.1101/2024.09.08.611922 — immunology — Posted on 2024-09-10
4017 Subcortical Auditory Deviance Detection in Humans: An ABR Study
Wetekam, J.; Gotta, N.; Lopez-Jury, L.; Hechavarria, J.; Koessl, M.
10.1101/2024.06.18.599524 — neuroscience — Posted on 2024-09-10
4019 Improving anxiety research: novel approach to reveal trait anxiety through summary measures of multiple states
Varga, Z. K.; Pejtsik, D.; Toth, M.; Balogh, Z.; Aliczki, M.; Szente, L.; Balla, G. Y.; Kontra, L.; Eckert, Z.; Zsolt, B.; Mikics, E.
10.1101/2023.06.01.543235 — neuroscience — Posted on 2024-09-10
4020 Single-cell transcriptomic changes in oligodendroglial lineage cells derived from Parkinson's disease patient-iPSCs with LRRK2-G2019S mutation
Dehestani, M.; Kessler, W.; Karmali, N.; Sun, W.; Volos, P.; Tsitkov, S.; Dhingra, A.; Rodriguez-Nieto, S.; Tietz, J.; Schafflick, D.; Fernandes, N.; Fitzgerald, J.; Fraenkel, E.; Gasser, T.; Rafiq, N. M.; Kuhlmann, T.; Bansal, V.
10.1101/2024.07.01.601392 — neuroscience — Posted on 2024-09-10
4022 Remote ischemic conditioning attenuates transneuronal degeneration and promotes stroke recovery via CD36-mediated efferocytosis.
Ju, H.; Kim, I.-d.; Pavlova, I.; Mu, S.; Park, K. W.; Minkler, J.; Madkoor, A.; Wang, W.; Wang, X.; Wu, Z.; Yang, J.; Febbraio, M.; Cave, J. W.; Cho, S.
10.1101/2024.09.03.611124 — neuroscience — Posted on 2024-09-10
4026 Comparative Analysis of Small Secreted Peptide Signaling during Defense Response: Insights from Vascular and Non-Vascular Plants
Lyapina, I.; Ganaeva, D.; Rogozhin, E. A.; Ryabukhina, E. V.; Ryazantsev, D. Y.; Lazarev, V.; Alieva, S. E.; Mamaeva, A.; Fesenko, I.
10.1101/2024.05.13.593875 — plant biology — Posted on 2024-09-10
4033 A near-complete genome assembly of the bearded dragon Pogona vitticeps provides insights into the origin of Pogona sex chromosomes
Guo, Q.; Pan, Y.; Dai, W.; Guo, F.; Zeng, T.; Chen, W.; Mi, Y.; Zhang, Y.; Shi, S.; Jiang, W.; Cai, H.; Wu, B.; Zhou, Y.; Wang, Y.; Yang, C.; Shi, X.; Yan, X.; Chen, J.; Cai, C.; Yang, J.; Xu, X.; Gu, Y.; Dong, Y.; Li, Q.
10.1101/2024.09.05.611321 — genomics — Posted on 2024-09-10
4034 A non-catalytic function for Rad18 in sustaining glioblastoma proliferation
Benbahouche, N. E.-H.; Kermi, C.; Siegfried, A.; Sefancikova, L.; Pascussi, J.-M.; Pannequin, J.; Moreaux, J.; Hugnot, J.-P.; Delisle, M.-B.; Moyal, E.; Uro-Coste, E.; Maiorano, D.
10.1101/2024.09.05.611406 — cancer biology — Posted on 2024-09-10
4036 Rare twin cysteine residues in the HIV-1 envelope variable region 1 link to neutralization escape and breadth development
Hesselman, M. C.; Zeeb, M.; Rusert, P.; Pasin, C.; Mamrosh, J.; Kariuki, S.; Sickmann, M.; Kaufmann, M. M.; Schmidt, D.; Friedrich, N.; Metzner, K. J.; Rindler, A.; Kuster, H.; Adams, C.; Thebus, R.; Huber, M.; Yerly, S.; Leuzinger, K.; Perreau, M.; Koller, R.; Dollenmaier, G.; Frigerio, S.; Westfall, D. H.; Deng, W.; DeCamp, A. C.; Juraska, M.; Edupuganti, S.; Mgodi, N.; Murrell, H.; Garrett, N.; Wagh, K.; Mullins, J. I.; Williamson, C.; Moore, P. L.; Günthard, H. F.; Kouyos, R. D.; Trkola, A.
10.1101/2024.09.05.611179 — immunology — Posted on 2024-09-10
4038 Notch-signaling is required for mediating between two pattern forming processes during head regeneration in Hydra polyps
Steichele, M.; Sauermann, L.; Pan, Q.; Moneer, J.; de la Porte, A.; Hess, M.; Mercker, M.; Strube, C.; Flaswinkel, H.; Jenewein, M.; Boettger, A.
10.1101/2024.02.02.578611 — developmental biology — Posted on 2024-09-10
4039 Gonadotrophs have a dual origin, with most derived from pituitary stem cells during minipuberty.
Sheridan, D.; Chakravarty, P.; Golan, G.; Shiakola, Y.; Galichet, C.; Mollard, P.; Melamed, P.; Lovell-Badge, R.; Rizzoti, K.
10.1101/2024.09.09.610834 — developmental biology — Posted on 2024-09-10
4040 Incompatibility groups of Pseudomonas plasmids revisited: comprehensive analysis of R-factors and their replicons
Nishimura, Y.; Kaneko, K.; Kamijo, T.; Isogai, N.; Tokuda, M.; Xie, H.; Tsuda, Y.; Hirabayashi, A.; Moriuchi, R.; Dohra, H.; Kimbara, K.; Suzuki-Minakuchi, C.; Nojiri, H.; Suzuki, H.; Suzuki, M.; Shintani, M.
10.1101/2024.09.03.610885 — microbiology — Posted on 2024-09-10
4043 Mast cells promote pathology and susceptibility in tuberculosis
Gupta, A.; Taneja, V.; Rangel-Moreno, J.; Abhimanyu, A.; Ahmed, M.; Naqvi, N.; Chauhan, K. S.; de Leon, D. T.-P.; Ramirez-Martinez, G.; Jimenez-Alvarez, L.; Luna-Rivero, C.; Zuniga, J.; Kaushal, D.; Khader, S.
10.1101/2024.09.04.611333 — immunology — Posted on 2024-09-10
4044 Ketogenic interventions restore cognition and modulate peripheral metabolic dysfunctions in Alzheimer's disease mouse models
M'Bra, P. E. H.; Hamilton, L. K.; Moquin-Beaudry, G.; Aubin, M.; Lyn-Mangahas, C.; Pratesi, F.; Brunet, E.; Castonguay, A.; Mailloux, S.; Galoppin, M.; Bernier, M.; Turri, M.; Vachon, A.; Mayhue, M.; Aumont, A.; Tetreault, M.; Plourde, M.; Fernandes, K. J. L.
10.1101/2024.09.04.610637 — neuroscience — Posted on 2024-09-10
4045 TMPRSS6 cleaves KCNE1 and causes arrhythmias in iron overload disease
Peischard, S.; Kastl, P.; Goerges, G.; Schreiber, J. A.; Verkerk, A. O.; Wilders, R.; Disse, P.; Hornung, I.; Klingmüller, U.; Steinbicker, A.; Rauner, M.; Vujic, M.; Rosenbauer, F.; Meuth, S.; Budde, T.; Pedersen, P. A.; Jepps, T. A.; Jespersen, T.; Strutz-Seebohm, N.; Seebohm, G.
10.1101/2024.09.04.611322 — physiology — Posted on 2024-09-10
4047 Diurnal regulation of SOS Pathway and Sodium Excretion Underlying Salinity Tolerance of Vigna marina
Noda, Y.; Wang, F.; Chankaew, S.; Ariga, H.; Muto, C.; Iki, Y.; Ohashi, H.; Takahashi, Y.; Sakai, H.; Iseki, K.; Ogiso-Tanaka, E.; Suzui, N.; Yin, Y.-G.; Miyoshi, Y.; Enomoto, K.; Kawachi, N.; Somta, P.; Furukawa, J.; Tomooka, N.; Naito, K.
10.1101/2024.03.26.586888 — plant biology — Posted on 2024-09-10
4054 Early life stress influences epilepsy outcomes in mice
Coleman, E. M.; White, M.; Antonoudiou, P.; Weiss, G. L.; Scarpa, G.; Stone, B.; Maguire, J.
10.1101/2024.09.09.612052 — neuroscience — Posted on 2024-09-10
4055 Behavioral state and stimulus strength regulate the role of somatostatin interneurons in stabilizing network activity
Cammarata, C. M.; Pei, Y.; Shields, B. C.; Lim, S. S. X.; Hawley, T.; Li, J. Y.; St. Amand, D.; Brunel, N.; Tadross, M. R.; Glickfeld, L. L.
10.1101/2024.09.09.612138 — neuroscience — Posted on 2024-09-10
4059 Human and bats genome robustness under COSMIC mutational signatures
Song, J.-H.; Zeng, Y.; Davalos, L. M.; MacCarthy, T.; Larijani, M.; Damaghi, M.
10.1101/2024.09.05.611453 — genomics — Posted on 2024-09-10
4060 Epigenetic priming of embryonic enhancer elements coordinates developmental gene networks
Todd, C. D.; Ijaz, J.; Torabi, F.; Dovgusha, O.; Bevan, S.; Cracknell, O.; Lohoff, T.; Clark, S.; Argelaguet, R.; Pearce, J.; Kafetzopoulos, I.; Santambrogio, A.; Nichols, J.; von Meyenn, F.; Guenesdogan, U.; Schoenfelder, S.; Reik, W.
10.1101/2024.09.09.611867 — developmental biology — Posted on 2024-09-10
4061 eIF3 engages with 3'-UTR termini of highly translated mRNAs
Mestre-Fos, S.; Ferguson, L.; Trinidad, M. I.; Ingolia, N.; Cate, J. H. D.
10.1101/2023.11.11.566681 — molecular biology — Posted on 2024-09-10
4063 Mitochondrial complex I deficiency occurs in skeletal muscle of a subgroup of individuals with Parkinson's disease
Kverneng, S. U.; Stige, K. E.; Berven, H.; Mostafavi, S.; Lundervold, K.; Brischigliaro, M.; Brakedal, B.; Skeie, G. O.; Flones, I. H.; Toker, L.; Fernandez-Vizarra, E.; Skogseth, R. E.; Haugarvoll, K.; Torres Cleuren, Y. N.; Dölle, C.; Nido, G. S.; Tzoulis, C.
10.1101/2024.09.09.611610 — neuroscience — Posted on 2024-09-09
4064 Three Subtypes Of Autism Spectrum Disorder With Transcriptomic Signatures Derived From Morphometric Similarity Networks
Jiang, H.; Chai, X.; Rodriguez Cruces, R.; Xie, K.; Kebets, V.; Wang, Y.; Weber, C.; He, Y.; Kember, J.; Poline, J.-B.; Bzdok, D.; Hong, S.-J.; Bernhardt, B.
10.1101/2024.09.06.611561 — neuroscience — Posted on 2024-09-10
4066 Adversarial learning enables unbiased organism-wide cross-species alignment of single-cell RNA data at scale
Cooper, S.; Diaz-Mejia, J. J.; Innes, B.; Williams, E.; Mendonca, D.; Focsa, O.; Nixon, A.; Singh, S.; Schuster, R.; Hinz, B.; Buechler, M.
10.1101/2024.08.11.607498 — genetics — Posted on 2024-09-09
4067 Evolutionary and Functional Analysis of Monoamine Oxidase C (MAO C): A Novel Member of the MAO Gene Family
Merello, G.; Olivares-Costa, M.; Basile, L.; Pastor, T. P.; Mendoza-Soto, P.; Padilla-Santiago, L.; Mardones, G.; Binda, C.; Opazo, J. C.
10.1101/2024.08.20.608864 — evolutionary biology — Posted on 2024-09-09
4068 Presynapses are mitophagy pit stops that prevent axon degeneration
Lam, W. K.; Lindblom, R. S. J.; Milky, B.; Mazzachi, P.; Hadian-Jazi, M.; Kung, C.; Khuu, G.; Uoselis, L.; Nguyen, T. N.; Skulsuppaisarn, M.; Saunders, T. L.; Schmidt, M. F.; Dewson, G.; Fogel, A. I.; Bardy, C.; Lazarou, M.
10.1101/2024.09.09.611943 — cell biology — Posted on 2024-09-09
4070 Osterix Facilitates Osteocytic Communication by Targeting Connexin43
wu, z.; chen, q.; gao, q.; Liang, m.; Zhou, y.; Zhu, L.; wang, j.; Shen, Y.; Jing, j.; Xie, J.; Liu, X.; zou, S.; Zhang, D.; Zhou, C.
10.1101/2024.09.09.611984 — cell biology — Posted on 2024-09-09
4071 Estrogen receptor alpha mediated repression of PRICKLE1 destabilizes REST and promotes uterine fibroid pathogenesis
McWilliams, M. M.; Koohestani, F.; Jefferson, W. N.; Gunewardena, S.; Shivashankar, K.; Wertenberger, R. A.; Williams, C. J.; Kumar, T. R.; Chennathukuzhi, V. M.
10.1101/2024.09.09.612036 — cell biology — Posted on 2024-09-09
4072 Volume electron microscopy reveals 3D synaptic nanoarchitecture in postmortem human prefrontal cortex
Glausier, J. R.; Bouchet-Marquis, C.; Maier, M.; Banks-Tibbs, T.; Wu, K.; Ning, J.; Melchitzky, D.; Lewis, D. A.; Freyberg, Z. A.
10.1101/2024.02.26.582174 — neuroscience — Posted on 2024-09-09
4074 NR2F2 Reactivation in Early-life Adipocyte Stem-like Cells Rescues Adipocyte Mitochondrial Oxidation
Das, S.; Varshney, R.; Farriester, J. W.; Kyere-Davies, G.; Martinez, A. E.; Hill, K.; Kinter, M.; Mullen, G. P.; Nagareddy, P. R.; Rudolph, M. C.
10.1101/2024.09.09.611047 — physiology — Posted on 2024-09-09
4075 Cancer-independent, second somatic NF1 mutation of normal tissues in neurofibromatosis type 1
Oliver, T. R. W.; Lawson, A. R. J.; Lee-Six, H.; Tollit, A.; Jung, H.; Hooks, Y.; Sanghvi, R.; Young, M. D.; Butler, T. M.; Nicola, P.; Treger, T. D.; Burke, G. A. A.; Aquilina, K.; Lobel, U.; Cortes-Ciriano, I.; Hargrave, D.; Jorgensen, M.; Jessop, F. A.; Coorens, T. H. H.; Flanagan, A. M.; Allinson, K.; Martincorena, I.; Jacques, T. S.; Behjati, S.
10.1101/2024.09.09.611411 — cancer biology — Posted on 2024-09-09
4076 Cisplatin reprogramming of protein phosphorylation
Qi, L.; Zhou, Y.; Hou, Y.; Luo, Q.; Xu, Y.; Liu, X.; Yu, W.; Li, X.; Xin, B.; Huang, Y.; Zhang, Y.; Jia, F.; Fang, T.; Wang, S.; Sadler, P.; Zhao, Y.; Wang, F.
10.1101/2024.02.28.582513 — cancer biology — Posted on 2024-09-09
4077 Extracellular vesicles regulate metastable phenotypes of lymphangioleiomyomatosis cells via shuttling ATP synthesis to pseudopodia and activation of integrin adhesion complexes.
Kalvala, A. K.; Silwal, A.; Patel, B.; Kasetti, A.; Shetty, K.; Cho, J.-H.; Lara, G.; Daugherity, B.; Diesler, R.; Pooladanda, V.; Rueda, B. R.; Henske, E. P.; Yu, J. J.; Markiewski, M. M.; Karbowniczek, M.
10.1101/2024.09.09.611297 — cancer biology — Posted on 2024-09-09
4079 Three-dimensional analysis of mitochondria in a patient-derived xenograft model of triple negative breast cancer reveals mitochondrial network remodeling following chemotherapy treatments
Berner, M. J.; Beasley, H. K.; Vue, Z.; Lane, A.; Vang, L.; Baek, M. L.; Marshall, A. G.; Killion, M.; Zeleke, F.; Shao, B.; Parker, D.; Peterson, A.; Rhoades, J. S.; Scudese, E.; Dobrolecki, L. E.; Lewis, M. T.; Hinton, A.; Echeverria, G. V.
10.1101/2024.09.09.611245 — cancer biology — Posted on 2024-09-09
4086 Dynamic Hydrogel Crosslink Strength Controls Yielding Characteristics and Cell Viability During Injection
Eckman, N.; Grosskopf, A. K.; Jiang, G.; Kamani, K.; Huang, M.; Schmittlein, B.; Heilshorn, S. C.; Rogers, S.; Appel, E.
10.1101/2024.08.16.608324 — bioengineering — Posted on 2024-09-09
4087 Three-step scalable production of extracellular vesicles from pancreatic beta cells in stirred tank bioreactors promotes cell maturation and release of ectosomes with preserved immunomodulatory properties
De Beaurepaire, L.; Dauphin, T.; Pruvost, Q.; Salama, A.; Dupont, A.; Dubreil, L.; Jegou, D.; Mignot, G.; Mahieu, B.; Herve, J.; Lieubeau, B.; Bach, J.-M.; Bosch, S.; Mosser, M.
10.1101/2024.09.05.611247 — bioengineering — Posted on 2024-09-09
4088 Analog epigenetic memory revealed by targeted chromatin editing
Palacios, S.; Bruno, S.; Weiss, R.; Salibi, E.; Kane, A.; Ilia, K.; Del Vecchio, D.
10.1101/2024.02.13.580200 — bioengineering — Posted on 2024-09-09
4089 Distinct modes of coupling between VCP, an essential unfoldase, and deubiquitinases
Vostal, L. E.; Dahan, N. E.; Zhang, W.; Reynolds, M. J.; Chait, B.; Kapoor, T. M.
10.1101/2024.09.08.611915 — biochemistry — Posted on 2024-09-09
4091 Preschool musicality is associated with school-age communication abilities through genes related to rhythmicity
de Hoyos, L.; Verhoef, E.; Okbay, A.; Vermeulen, J. R.; Figaroa, C.; Lense, M.; Fisher, S. E.; Gordon, R. L.; St Pourcain, B.
10.1101/2024.09.09.611603 — genetics — Posted on 2024-09-09
4093 Introduced trout hinder the recovery of native fish following an extreme flood disturbance
Lennox, R. S.; McIntosh, A. R.; Lai, H. R.; Stouffer, D. B.; Boddy, N. C.; Zammit, C.; Tonkin, J. D.
10.1101/2024.09.05.611377 — ecology — Posted on 2024-09-09
4094 Gonadotrophs have a dual origin, with most derived from pituitary stem cells during minipuberty.
Sheridan, D.; Chakravarty, P.; Golan, G.; Shiakola, Y.; Galichet, C.; Mollard, P.; Melamed, P.; Lovell-Badge, R.; Rizzoti, K.
10.1101/2024.09.09.610834 — developmental biology — Posted on 2024-09-09
4095 A Nerve-Fibroblast Axis in Mammalian Lung Fibrosis
Ishikawa, G.; Peng, X.; McGovern, J.; Ghincea, A.; Woo, S.; Okuno, D.; Yu, S.; Lee, C. J.; Liu, A.; Saber, T.; Hu, B.; Sun, Y.; Sun, H.; Jumaily, K. A.; Feghali-Bostwick, C.; Sumida, T. S.; Sauler, M.; Ryu, C.; Herzog, E. L.
10.1101/2024.09.09.611003 — cell biology — Posted on 2024-09-09
4097 Maspin/SerpinB5 is a cytoskeleton-binding protein that regulates epithelial cell shape
da Silva, L.; Paim, L.; Menezes, A. P.; da Cunha, J. P.; Bechstedt, S.; Cella, N.
10.1101/2024.09.09.612024 — cell biology — Posted on 2024-09-09
4098 The Structure of Cilium Inner Junctions Revealed by Electron Cryo-tomography
Li, S.; Fernandez, J.-J.; Ruehle, M. D.; Howard-Till, R. A.; Fabritius, A. S.; Pearson, C. G.; Agard, D. A.; Winey, M.
10.1101/2024.09.09.612100 — cell biology — Posted on 2024-09-09
4099 Balancing limited resources in actin networks competition
Guerin, C.; N'Diaye, A.-B.; Gressin, L.; Mogilner, A.; Thery, M.; Blanchoin, L.; Colin, A.
10.1101/2024.09.09.612098 — cell biology — Posted on 2024-09-09
4101 Novel Pannexin 1 isoform is increased in cancer
O'Donnell, B. L.; Stefan, D.; Chiu, Y.-H.; Zeitz, M.; Tang, J.; Johnston, D.; Leighton, S.; Van Kessell, C.; Barr, K.; Gyenis, L.; Freeman, T.; Kelly, J. J.; Sayedyahossein, S.; Litchfield, D. W.; Roth, K.; Smyth, J. W.; Hebb, M.; Ronald, J.; Bayliss, D. A.; Penuela, S.
10.1101/2024.09.09.612143 — cell biology — Posted on 2024-09-09
4105 Cryo-EM uncovers a sequential mechanism for RNA polymerase I pausing and stalling at abasic DNA lesions
Santos-Aledo, A.; Plaza-Pegueroles, A.; Sanz-Murillo, M.; Ruiz, F. M.; Xu, J.; Gil-Carton, D.; Wang, D.; Fernandez-Tornero, C.
10.1101/2024.09.09.611646 — molecular biology — Posted on 2024-09-09
4106 LncRNA Snhg3 Aggravates Hepatic Steatosis via PPARγ Signaling
Xie, X.; Gao, M.; Zhao, W.; Li, C.; Zhang, W.; Yang, J.; Zhang, Y.; Chen, E.; Guo, Y.; Guo, Z.; Zhang, M.; Ngowi, E. E.; Wang, H.; Wang, X.; Zhu, Y.; Wang, Y.; Li, X.; Yao, H.; Yan, L.; Fang, F.; Li, M.; Qiao, A.; Liu, X.
10.1101/2024.03.22.586335 — molecular biology — Posted on 2024-09-09
4107 Genomic and metabolic characterization of Trueperella pyogenes isolated from domestic and wild animals
Magossi, G.; James-Gzyl, K. E.; Holman, D. B.; Nagaraja, T. G.; Amachawadi, R. G.; Amat, S.
10.1101/2024.09.09.612034 — microbiology — Posted on 2024-09-09
4108 A Comparative assessment of T-Cell response of Healthy donors and Acute Graft-versus-Host-Disease Patients: Customizing immune monitoring platform
Mendiratta, M.; Mendiratta, M.; Rai, S.; Gupta, R.; Bakhshi, S.; Aggarwal, M.; Gupta, A. K.; Prakash, H.; Mohanty, S.; Sahoo, R. K.
10.1101/2024.09.05.611044 — immunology — Posted on 2024-09-09
4110 Human assembloids reveal the consequences of CACNA1G gene variants in the thalamocortical pathway
Kim, J.-i.; Miura, Y.; Li, M.-Y.; Revah, O.; Selvaraj, S.; Birey, F.; Meng, X.; Thete, M. V.; Pavlov, S. D.; Anderson, J.; Pasca, A. M.; Porteus, M. H.; Huguenard, J. R.; Pasca, S. P.
10.1101/2023.03.15.530726 — neuroscience — Posted on 2024-09-09
4111 Use of the non-paretic arm reflects a habitual behaviour in chronic stroke
Sporn, S.; Bonyadi, E.; Fathana, R.; Triccas Tedesco, L.; Coll, M.; Bestmann, S.; Ward, N. S.
10.1101/2024.09.09.611968 — neuroscience — Posted on 2024-09-09
4112 Chemically induced senescence prompts functional changes in human microglia-like cells
Armanville, S.; Tocco, C.; Haj Mohamad, Z.; Clarke, D.; Robitaille, R.; Drouin-Ouellet, J.
10.1101/2024.02.27.582168 — neuroscience — Posted on 2024-09-09
4113 An antisense oligonucleotide-based strategy to ameliorate cognitive dysfunction in the 22q11.2 Deletion Syndrome
Thakur, P.; Lackinger, M.; Diamantopoulou, A.; Rao, S.; Chen, Y.; Khalizova, K.; Ferng, A.; Mazur, C.; Kordasiewicz, H.; Shprintzen, R. J.; Markx, S.; Xu, B.; Gogos, J. A.
10.1101/2022.03.01.482495 — neuroscience — Posted on 2024-09-09
4115 Bradykinesia and postural instability in a model of prodromal Synucleinopathy with alpha-Synuclein aggregation in the gigantocellular nuclei.
Theologidis, V.; Ferreira, S. A.; Jensen, N. M.; Gomes Moreira, D.; Ahlgreen, O. A.; Hansen, M. W.; Rosenberg, E. D.; Richner, M.; Faress, I.; Gram, H.; Jensen, P. H.; Borghammer, P.; Nyengaard, J. R.; Romero-Ramos, M.; Vaegter, C. B.; van de Berg, W. D. J.; Van Den Berge, N.; Jan, A.
10.1101/2024.09.05.610956 — neuroscience — Posted on 2024-09-09
4117 Photoreceptor degeneration has heterogeneous effects on functional retinal ganglion cell types
Dyszkant, N.; Oesterle, J.; Qiu, Y.; Harrer, M.; Schubert, T.; Gonschorek, D.; Euler, T.
10.1101/2024.09.06.610955 — neuroscience — Posted on 2024-09-09
4118 Modeling Attention and Binding in the Brain through Bidirectional Recurrent Gating
Salehinajafabadi, S.; Lei, J.; Benjamin, A. S.; Muller, K. R.; Kording, K. P.
10.1101/2024.09.09.612033 — neuroscience — Posted on 2024-09-09
4119 Cross-species brain-wide mapping reveals a conserved and coordinated network engaged by NAc DBS
Feng, A.; Barbosa, D. A. N.; Casey, A. B.; Rijsketic, D. R.; Salgado, J. S.; Huang, H.; Malenka, R. C.; Dora, H.; Miller, K. J.; Halpern, C.; Heifets, B. D.
10.1101/2024.09.08.611940 — neuroscience — Posted on 2024-09-09
4120 Applicability of Castration Model in Sex Difference Studies: Insights from Metabolome and Transcriptome Analyses
Jiang, J.; Ge, N.; Wang, Y.; Qi, J.; Wen, G.; Gu, X.; Yu, X.; Shao, M.; Luo, Y.; Gu, K.; Lin, F.; Yang, S.; Wei, W.
10.1101/2023.12.27.573488 — systems biology — Posted on 2024-09-09
4125 Endophytic pyrroloquinoline quinone enhances banana growth and immunity against Fusarium wilt for plant-microbe mutualisms
Hung, S.-H. W.; Yu, M.-Y.; Liu, C.-H.; Huang, T.-C.; Peng, J.-H.; Jang, N.-Y.; Kuo, C.-H.; Yang, Y.-L.; Ho, Y.-N.; Chiang, E.-P. I.; Hwang, H.-H.; Huang, C.-C.
10.1101/2024.08.20.608638 — plant biology — Posted on 2024-09-09
4129 Maturation of human cardiac organoids are required for disease modelling and drug discovery
Pocock, M.; Reid, J.; Robinson, H.; Charitakis, N.; Krycer, J.; Foster, S.; Tuano, N.; Fitzsimmons, R.; Lor, M.; Howden, S.; Vlahos, K.; Watt, K.; Piers, A.; Voges, H.; Fortuna, P.; Rae, J.; Parton, R.; Weintraub, R.; Konstantinov, I.; Elliott, D.; Ramialison, M.; Porrello, E.; Mills, R.; Hudson, J.
10.1101/2024.09.05.611336 — bioengineering — Posted on 2024-09-09
4131 Comparative analysis of uncoupled succinate production by the FeII/2-oxoglutarate-dependent dioxygenases
Das, S.; Keerthana, C. L.; Ranjan, S.; Seenivasan, G.; Tuti, N.; Shaji, U.; Meur, G.; Anindya, R.
10.1101/2024.09.09.612061 — biochemistry — Posted on 2024-09-09
4132 A secondary β-hydroxybutyrate metabolic pathway linked to energy balance
Moya-Garzon, M. D.; Wang, M.; Li, V. L.; Wei, W.; Tung, A. S.-H.; Raun, S. H.; Zhao, M.; Coassolo, L.; Islam, H.; Oliveira, B.; Dai, Y.; Spaas, J.; Delgado-Gonzalez, A.; Donoso, K.; Alvarez-Buylla, A.; Franco-Montalban, F.; Letian, A.; Ward, C.; Liu, L.; Svensson, K. J.; Goldberg, E. L.; Gardner, C. D.; Little, J. P.; Banik, S. M.; Xu, Y.; Long, J. Z.
10.1101/2024.09.09.612087 — biochemistry — Posted on 2024-09-09
4134 Comparing newly developed SNP barcode panels with microsatellites to explore population genetics of malaria parasites in the Peruvian Amazon
Cabrera-Sosa, L.; Safarpour, M.; Kattenberg, J. H.; Ramirez, R.; Vinetz, J. M.; Rosanas-Urgell, A.; Gamboa, D.; Delgado-Ratto, C.
10.1101/2024.09.09.611954 — genomics — Posted on 2024-09-09
4135 Transcription factor networks disproportionately enrich for heritability of blood cell phenotypes
Martin-Rufino, J. D.; Caulier, A.; Lee, S.; Castano, N.; King, E.; Joubran, S.; Jones, M.; Goldman, S. R.; Arora, U. P.; Wahlster, L.; Lander, E. S.; Sankaran, V. G.
10.1101/2024.09.09.611392 — genomics — Posted on 2024-09-09
4136 Cost-effective solutions for high-throughput enzymatic DNA methylation sequencing
Longtin, A.; Watowich, M. M.; Sadoughi, B.; Petersen, R.; Brosnan, S. F.; Buetow, K.; Cai, Q.; Gurven, M. D.; Highland, H. M.; Huang, Y.-T.; Kaplan, H.; Kraft, T. S.; Lim, Y. A. L.; Long, J.; Melin, A. D.; Roberson, J.; Ng, K.-S.; Stieglitz, J.; Trumble, B. C.; Venkataraman, V. V.; Wallace, I. J.; Wu, J.; Snyder-Mackler, N.; Jones, A.; Bick, A. G.; Lea, A.
10.1101/2024.09.09.612068 — genomics — Posted on 2024-09-09
4137 The genome sequence of the Violet Carpenter Bee, Xylocopa violacea (Linnaeus, 1785): a hymenopteran species undergoing range expansion.
Nash, W.; Man, A.; McTaggart, S.; Baker, K.; Barker, T.; Catchpole, L.; Durrant, A.; Gharbi, K.; Irish, N.; Kaithakottil, G.; Ku, D.; Providence, A.; Shaw, F.; Swarbreck, D.; Watkins, C.; Mc Cartney, A.; Formenti, G.; Mouton, A.; Vella, N.; von Reumont, B. M.; Vella, A.; Haerty, W.
10.1101/2024.04.03.587942 — genomics — Posted on 2024-09-09
4138 High-quality peptide evidence for annotating non-canonical open reading frames as human proteins
Deutsch, E. W.; Kok, L. W.; Mudge, J. M.; Ruiz-Orera, J.; Fierro-Monti, I.; Sun, Z.; Abelin, J. G.; Alba, M. M.; Aspden, J. L.; Bazzini, A. A.; Bruford, E.; Brunet, M. A.; Calviello, L.; Carr, S. A.; Carvunis, A.-R.; Chothani, S.; Clauwaert, J.; Dean, K.; Faridi, P.; Frankish, A.; Hubner, N.; Ingolia, N.; Magrane, M.; Martin, M. J.; Martinez, T. F.; Menschaert, G.; Ohler, U.; Orchard, S.; Rackham, O.; Roucou, X.; Slavoff, S. A.; Valen, E.; Wacholder, A. C.; Weissman, J. S.; Wu, W.; Xie, Z.; Choudhary, J.; Bassani-Sternberg, M.; Vizcaino, J. A.; Ternette, N.; Moritz, R. L.; Prensner, J.; van He
10.1101/2024.09.09.612016 — molecular biology — Posted on 2024-09-09
4139 The landscape of Arabidopsis tRNA aminoacylation
Ceriotti, L. F.; Warren, J. M.; Sanchez-Puerta, M. V.; Sloan, D. B.
10.1101/2024.09.09.612099 — molecular biology — Posted on 2024-09-09
4140 SIRT6 loss causes intervertebral disc degeneration in mice by promoting senescence and SASP status
Ramteke, P.; Watson, B.; Toci, M.; Tran, V.; Johnston, S.; Tsingas, M.; Barve, R.; Mitra, R.; Loeser, R.; Collins, J.; Risbud, M.
10.1101/2024.09.09.612072 — molecular biology — Posted on 2024-09-09
4143 Antibiotic resistance detection and concomitant species identification of ESKAPE pathogens by proteomics
Blumenscheit, C.; Pfeifer, Y.; Werner, G.; John, C.; Layer-Nicolaou, F.; Schneider, A.; Lasch, P.; Doellinger, J.
10.1101/2024.09.09.612008 — microbiology — Posted on 2024-09-09
4144 Discovery of novel quinoline papain-like protease inhibitors for COVID-19 through topology constrained molecular generative model
Shang, J.; Ran, T.; Lu, Y.; Yang, Q.; Zhang, G.; Zhou, P.; Li, W.; Xu, M.; Dai, M.; Zhong, J.; Chen, H.; He, P.; Zhou, A.; Xue, B.; Chen, J.; Zhang, J.; Wu, K.; Wu, X.; Tang, M.; Chen, X.; Chen, H.
10.1101/2024.09.07.611841 — microbiology — Posted on 2024-09-09
4145 Pseudomonas aeruginosa faces a fitness trade-off between mucosal colonization and antibiotic tolerance during airway infections
Meirelles, L. A.; Vayena, E.; Debache, A.; Schmidt, E.; Rossy, T.; Distler, T.; Hatzimanikatis, V.; Persat, A.
10.1101/2024.09.09.611974 — microbiology — Posted on 2024-09-09
4147 Prolonged thermal stress enhances mosquito tolerance to viral infection
Perdomo, H. D.; Khorramnejad, A.; Cham, N. M.; Kropf, A.; Sogliani, D.; Bonizzoni, M.
10.1101/2024.09.06.611661 — immunology — Posted on 2024-09-09
4149 Selective deuteration of an RNA:RNA complex for structural analysis using small-angle scattering
Munsayac, A.; Leite, W. C.; Hopkins, J. B.; Hall, I.; O'Neill, H. M.; Keane, S. C.
10.1101/2024.09.09.612093 — biophysics — Posted on 2024-09-09
4150 Interaction with AK2A links AIFM1 to cellular energy metabolism
Rothemann, R. A.; Pavlenko, E.; Mondal, M.; Gerlich, S.; Grobushkin, P.; Mostert, S.; Racho, J.; Weiss, K.; Stobbe, D.; Stillger, K.; Lapacz, K.; Salscheider, S. L.; Petrungaro, C.; Ehninger, D.; Nguyen, T. H. D.; Dengjel, J.; Neundorf, I.; Bano, D.; Poepsel, S.; Riemer, J.
10.1101/2024.09.09.611957 — biochemistry — Posted on 2024-09-09
4151 CRISPR-CLEAR: Nucleotide-Resolution Mapping of Regulatory Elements via Allelic Readout of Tiled Base Editing
Becerra, B.; Wittibschlager, S.; Patel, Z. M.; Kutschat, A.; Delano, J.; Karjalainen, A.; Wu, T.; Starrs, M.; Jankowiak, M.; Bauer, D.; Seruggia, D.; Pinello, L.
10.1101/2024.09.09.612085 — genomics — Posted on 2024-09-09
4152 A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and combines a direct antiviral effect with subtle boosting of interferon
Van Loy, B.; Pujol, E.; Kamata, K.; Lee, X. Y.; Bakirtzoglou, N.; Van Berwaer, R.; Vandeput, J.; Persoons, L.; De Wijngaert, B.; Goovaerts, Q.; Noppen, S.; Ahmadzadeh, K.; Martin-Lopez, J.; Escriche, C.; Vanmechelen, B.; Krasniqi, B.; Singh, A. K.; Maes, P.; Matthys, P.; Dehaen, W.; Rozenski, J.; Das, K.; Voet, A.; Vazquez, S.; Naesens, L. M.; Stevaert, A.
10.1101/2024.09.09.611961 — microbiology — Posted on 2024-09-09
4155 Urinary multi-omics reveal non-invasive diagnostic biomarkers in clear cell renal cell carcinoma
Jonsson, G.; Hofmann, M.; Oliveira, T.; Lemberger, U.; Stejskal, K.; Krssakova, G.; Sakic, I.; Novatchkova, M.; Mereiter, S.; Grabmann, G.; Koecher, T.; Kikic, Z.; Rechberger, G. N.; Zuellig, T.; Englinger, B.; Schmidinger, M.; Penninger, J. M.
10.1101/2024.08.12.607453 — cancer biology — Posted on 2024-09-09
4156 BCL2L13 Influences Autophagy and Ceramide Metabolism without Affecting Temozolomide Resistance in Glioblastoma
Clark, C.; Barzegar Behrooz, A.; Da Silva Rosa, S. C.; Jacobs, J.; Weng, X.; Srivastava, A.; Vitorino, R.; Ande, S. R.; Ravandi, A.; Dhingra, S.; Pecic, S.; Miller, D.; Shojaei, S.; Ghavami, S.
10.1101/2024.08.23.609447 — cancer biology — Posted on 2024-09-09
4157 Genomic features of NF1-associated peripheral nerve sheath tumors: a cohort analysis from the Johns Hopkins NF1 biospecimen repository
Banerjee, J.; Lyu, Y.; Makri, S. C.; Scott, A. J.; Zhang, L.; Calizo, A.; Pollard, K.; Yang, K.; Gross, J. M.; Wang, J.; Levin, A. S.; Belzberg, A. J.; Romo, C. G.; Allaway, R. J.; Blakeley, J. O.; Hirbe, A. C.; Pratilas, C. A.
10.1101/2024.01.23.576977 — bioinformatics — Posted on 2024-09-09
4158 Long-read sequencing transcriptome quantification with lr-kallisto
Loving, R. K.; Sullivan, D. K.; Reese, F.; Rebboah, E.; Sakr, J.; Rezaie, N.; Liang, H. Y.; Filimban, G.; Kawauchi, S.; Oakes, C.; Trout, D.; Williams, B. A.; MacGregor, G.; Wold, B.; Mortazavi, A.; Pachter, L.
10.1101/2024.07.19.604364 — bioinformatics — Posted on 2024-09-09
4160 Deep Plasma Proteome Profiling by Modulating Single Nanoparticle Protein Corona with Small Molecules
Ashkarran, A. A.; Gharibi, H.; Sadeghi, S. A.; Modaresi, S. M.; Wang, Q.; Lin, T.-J.; Yerima, G.; Tamadon, A.; Sayadi, M.; Jafari, M.; Lin, Z.; Ritz, D.; Kakhniashvili, D.; Guha, A.; Mofrad, M.; Sun, L.; Landry, M. P.; Dibavar, A. S.; Mahmoudi, M.
10.1101/2024.03.06.582595 — bioengineering — Posted on 2024-09-09
4161 Atp1a2 and Kcnj9 are candidate genes underlying sensitivity to oxycodone-induced locomotor activation and withdrawal-induced anxiety-like behaviors in C57BL/6 substrains
Goldberg, L. R.; Baskin, B. M.; Adla, Y.; Beierle, J. A.; Kelliher, J. C.; Yao, E. J.; Kirkpatrick, S. L.; Reed, E. R.; Jenkins, D. F.; Cox, J.; Luong, A. M.; Luttik, K. P.; Scotellaro, J. A.; Drescher, T. A.; Crotts, S. B.; Yazdani, N.; Ferris, M. T. R.; Johnson, W. E.; Mulligan, M. K.; Bryant, C. D.
10.1101/2024.04.16.589731 — genetics — Posted on 2024-09-09
4162 Functional insights into the effect of feralisation on the gut microbiota of cats worldwide
Aizpurua, O.; Bolt Botnen, A.; Eisenhofer, R.; Odriozola, I.; Santos-Bay, L.; Bjornsen, M. B.; Gilbert, M. T. P.; Alberdi, A.
10.1101/2024.09.04.611329 — evolutionary biology — Posted on 2024-09-09
4163 Deciphering the Cell-Specific Transcript Heterogeneity and Alternative Splicing during the Early Embryonic Development of Zebrafish
Lin, X.; Wang, X.; Liu, C.; Liu, C.; Zeng, T.; Yuan, Z.; Hu, M.; Xiang, R.; Zhao, K.; Zhou, J.; Yang, S.; Wang, Y.; Meng, K.; Wang, H.; He, G.; Zhao, R.; Liu, J.; Huang, Y.; Pan, J.; Wang, J.; Chen, J.; Guo, F.; Dong, Y.; Xu, X.; Luo, D.; Gu, Y.; Liu, L.; Dong, Z.; Chen, L.
10.1101/2024.09.08.611790 — developmental biology — Posted on 2024-09-09
4166 CLEC18A interacts with sulfated GAGs and controls clear cell renal cell carcinoma progression
Jonsson, G.; Hofmann, M.; Mereiter, S.; Hartley-Tassell, L.; Sakic, I.; Oliveira, T.; Hoffmann, D.; Novatchkova, M.; Schleiffer, A.; Penninger, J. M.
10.1101/2024.07.08.602586 — cancer biology — Posted on 2024-09-09
4168 Improving Inverse Folding models at Protein Stability Prediction without additional Training or Data
Dutton, O.; Bottaro, S.; Invernizzi, M.; Redl, I.; Chung, A.; Hoffmann, F.; Henderson, L.; Ruschetta, S.; Airoldi, F.; Owens, B. M.; Foerch, P.; Fisicaro, C.; Tamiola, K.
10.1101/2024.06.15.599145 — biophysics — Posted on 2024-09-09
4169 CoCoPyE: feature engineering for learning and prediction of genome quality indices
Birth, N.; Leppich, N.; Schirmacher, J.; Andreae, N.; Steinkamp, R.; Blanke, M.; Meinicke, P.
10.1101/2024.02.07.579156 — bioinformatics — Posted on 2024-09-09
4172 CellSeg3D: self-supervised 3D cell segmentation for light-sheet microscopy
Achard, C.; Kousi, T.; Frey, M.; Vidal, M.; Paychere, Y.; Hofmann, C.; Iqbal, A.; Hausmann, S. B.; Pages, S.; Mathis, M. W.
10.1101/2024.05.17.594691 — cell biology — Posted on 2024-09-09
4173 BrainSuite BIDS App: Containerized Workflows for MRI Analysis
Kim, Y.; Joshi, A. A.; Choi, S.; Joshi, S. H.; Bhushan, C.; Varadarajan, D.; Haldar, J. P.; Leahy, R. M.; Shattuck, D. W.
10.1101/2023.03.14.532686 — neuroscience — Posted on 2024-09-09
4177 GENETIC DIVERSITY OF T. B. RHODESIENSE SERUM RESISTANCE ASSOCIATED GENE IN MALAWIAN ISOLATES
Nambala, P.; Claucus, C.; Noyes, H.; MacLeod, A.; Namulondo, J.; Nyangiri, O.; Musaya, J.; Matovu, E.; Alibu, P. V.; Nerima, B.; Chammudzi, P.; Mulindwa, J.
10.1101/2024.09.07.611819 — genomics — Posted on 2024-09-09
4178 An improved tetracycline-inducible expression system for fission yeast
Lyu, X.-H.; Yang, Y.-S.; Pan, Z.-Q.; Ning, S.-K.; Suo, F.; Du, L.-L.
10.1101/2024.06.22.600193 — genetics — Posted on 2024-09-09
4179 Surface lipids influence developmental and species-specific chemical signalling in nematodes
Kotowska, A. M.; Hiramatsu, F.; Alexander, M. R.; Scurr, D. J.; Lightfoot, J. W.; Chauhan, V. M.
10.1101/2024.04.24.590549 — systems biology — Posted on 2024-09-09
4181 Neural Circuit Underlying Individual differences in Visual Escape Habituation
Liu, X.; Lai, J.; Han, C.; Huang, K.; Yang, Q.; Liu, Y.; Zhu, X.; Wei, P.; Tan, L.; Xu, F.; Wang, L.
10.1101/2024.09.05.611366 — neuroscience — Posted on 2024-09-09
4182 Under or Over? Tracing Complex DNA Structures with High-Resolution Atomic Force Microscopy
Holmes, E. P.; Gamill, M. C.; Provan, J. I.; Wiggins, L.; Ruskova, R.; Whittle, S.; Catley, T. E.; Main, K. H. S.; Shephard, N.; Bryant, H. E.; Gilhooly, N. S.; Gambus, A.; Racko, D.; Colloms, S. D.; Pyne, A. L. B.
10.1101/2024.06.28.601212 — biophysics — Posted on 2024-09-09
4184 Cross-species interactome analysis uncovers a conserved selective autophagy mechanism for protein quality control in plants
Hernandez, V. S. d. M.; Garcia, M. M. N.; Clavel, M.; Papareddy, R. K.; Andreev, V. I.; Gao, P.; De la Concepcion, J. C.; Mathur, V.; Picchianti, L.; Grujic, N.; Kobylinska, R.; Abdrakhmanov, A.; Duverge, H.; Anand, G.; Leibrock, N.; Bianchi, A.; Crawford, T.; Argiro, L.; Mohseni, A.; Leon, M. G.; Matuszkiewickz, M.; Raffeiner, M.; Wun, C.-L.; Kanne, J. V.; Meinhart, A.; Roitinger, E.; Baurle, I.; Kang, B.-H.; Petersen, M.; Ustun, S.; Kulathu, Y.; Clausen, T.; Ramundo, S.; Dagdas, Y.
10.1101/2024.09.08.611708 — plant biology — Posted on 2024-09-09
4189 A robust unsupervised clustering approach for high-dimensional biological imaging data reveals shared drug-induced morphological signatures
Bao, S. C.; Mizikovsky, D.; Pishas, K.; Zhao, Q.; Cowley, K. J.; Marinovic, E.; Carey, M.; Campbell, I.; Simpson, K. J.; Cheasley, D.; Palpant, N.
10.1101/2024.09.05.611300 — bioinformatics — Posted on 2024-09-09
4191 Functional insights into the effect of feralisation on the gut microbiota of cats worldwide
Aizpurua, O.; Bolt Botnen, A.; Eisenhofer, R.; Odriozola, I.; Santos-Bay, L.; Bjornsen, M. B.; Alberdi, A.
10.1101/2024.09.04.611329 — evolutionary biology — Posted on 2024-09-09
4193 Fuzzy ripple artifact in high resolution fMRI: identification, cause, and mitigation
Huber, L.; Stirnberg, R.; Morgan, A. T.; Feinberg, D.; Ehses, P.; Gulban, O. F.; Koiso, K.; Gephart, I.; Swegle, S.; Wardle, S. G.; Persichetti, A.; Beckett, A.; Stoecker, T.; Boulant, N.; Poser, B.; Bandettini, P.
10.1101/2024.09.04.611294 — neuroscience — Posted on 2024-09-09
4194 Restoring transient connectivity during development improves dysfunctions in fragile X mice
Dumontier, D.; Liebman, S. A.; Le, V.-H.; George, S.; Valdemar, D.; Van Aelst, L.; Pouchelon, G.
10.1101/2024.09.08.611918 — neuroscience — Posted on 2024-09-09
4195 Additions to the list of arthropods of Reunion Island
Nibouche, S.; Sadeyen, J.; Dervin, S.; Gauche, M.; Merion, S.; Minatchy, J.; Fontaine, R.; Reynaud, P.; Michel, B.
10.1101/2024.09.03.610934 — zoology — Posted on 2024-09-09
4197 Deciphering transcriptional programming during lupin (Lupinus angustifolius) seed development using RNA-seq
WAINAINA, V.; Rathjen, T.; Hughes, T.; Marquardt, A.; Fletcher, N.; Casarotto, H.; McNeil, M.; McElroy, K.; Gao, L.-L.
10.1101/2024.09.05.611346 — plant biology — Posted on 2024-09-09
4199 MaskMol: Knowledge-guided Molecular Image Pre-Training Framework for Activity Cliffs with Pixel Masking
cheng, Z.; Xiang, H.; Ma, P.; Li, Z.; Jin, X.; Yang, X.; Lin, J.; Song, B.; Deng, Y.; Feng, X.; Deng, C.; Zeng, X.
10.1101/2024.09.04.611324 — bioinformatics — Posted on 2024-09-09
4201 Gliogenesis from the subventricular zone modulates the extracellular matrix at the glial scar after brain ischemia
Ardaya, M.; Tiveron, M.-C.; Cremer, H.; Dehay, B.; Perez-Cerda, F.; Matute, C.; Soria, F. N.; Cavaliere, F.
10.1101/2023.12.30.573719 — neuroscience — Posted on 2024-09-09
4206 Deciphering the Cell Specific Transcript Heterogeneity and Alternative Splicing during the Early Embryonic Development of Zebrafish
Lin, X.; Wang, X.; Liu, C.; Liu, C.; Zeng, T.; Yuan, Z.; Hu, M.; Xiang, R.; Zhao, K.; Zhou, J.; Yang, S.; Wang, Y.; Meng, K.; Wang, H.; He, G.; Zhao, R.; Liu, J.; Huang, Y.; Pan, J.; Wang, J.; Chen, J.; Guo, F.; Dong, Y.; Xu, X.; Luo, D.; Gu, Y.; Liu, L.; Dong, Z.; Chen, L.
10.1101/2024.09.08.611790 — developmental biology — Posted on 2024-09-09
4209 Photochemical processes drive thermal responses of dissolved organic matter in the dark ocean
Hu, A.; Cui, Y.; Bercovici, S.; Tanentzap, A.; Lennon, J.; Lin, X.; Yang, Y.; Liu, Y.; Osterholz, H.; Dong, H.; Lu, Y.; Jiao, N.; Wang, J.
10.1101/2024.09.06.611638 — ecology — Posted on 2024-09-09
4213 A blended genome and exome sequencing method captures genetic variation in an unbiased, high-quality, and cost-effective manner
Boltz, T. A.; Chu, B. B.; Liao, C.; Sealock, J. M.; Ye, R.; Majara, L.; Fu, J. M.; Service, S.; Zhan, L.; Medland, S. E.; Chapman, S. B.; Rubinacci, S.; DeFelice, M.; Grimsby, J. L.; Abebe, T.; Alemayehu, M.; Ashaba, F. K.; Atkinson, E. G.; Bigdeli, T.; Bradway, A. B.; Brand, H.; Chibnik, L. B.; Fekadu, A.; Gatzen, M.; Gelaye, B.; Gichuru, S.; Gildea, M. L.; Hill, T. C.; Huang, H.; Hubbard, K. M.; Injera, W. E.; James, R.; Joloba, M.; Kachulis, C.; Kalmbach, P. R.; Kamulegeya, R.; Kigen, G.; Kim, S.; Koen, N.; Kwobah, E. K.; Kyebuzibwa, J.; Lee, S.; Lennon, N. J.; Lind, P. A.; Lopera-Maya, E.
10.1101/2024.09.06.611689 — genomics — Posted on 2024-09-09
4215 Novel derivatives of BCV and (S)-HPMPA inhibit orthopoxviruses and human adenoviruses more potently than BCV
Zhang, Y.; Wan, Y.; Guo, C.; Zhu, Z.; Qiu, C.; Lu, J.; Zhou, Y.; Zheng, J.; Dai, F.; Cheng, X.; Deng, K.; Wang, W.; Wang, Y.; Zhang, W.
10.1101/2024.08.30.610570 — microbiology — Posted on 2024-09-09
4217 Tracing the evolution of single-cell cancer 3D genomes: an atlas for cancer gene discovery
Liu, M.; Jin, S.; Agabiti, S. S.; Jensen, T. B.; Yang, T.; Radda, J. S. D.; Ruiz, C. F.; Baldissera, G.; Rajaei, M.; Townsend, J. P.; Muzumdar, M. D.; Wang, S.
10.1101/2023.07.23.550157 — cell biology — Posted on 2024-09-09
4219 Proliferation and differentiation of intestinal stem cells depends on the zinc finger transcription factor BCL11/Chronophage
Redhai, S.; Hirschmueller, N.; Wang, T.; Bahuguna, S.; Leible, S.; Peidli, S.; Valentini, E.; Kharuk, S.; Holzem, M.; Braeckow, L.; Port, F.; Ibberson, D.; Huber, W.; Boutros, M.
10.1101/2024.09.08.611891 — developmental biology — Posted on 2024-09-09
4222 Reward history guides focal attention in whisker somatosensory cortex
Ramamurthy, D. L.; Rodriguez, L.; Cen, C.; Li, S.; Chen, A.; Feldman, D. E.
10.1101/2024.07.17.603927 — neuroscience — Posted on 2024-09-09
4223 Deciphering the Cell Specific Transcript Heterogeneity and Alternative Splicing during the Early Embryonic Development of Zebrafish
Lin, X.; Wang, X.; Liu, C.; Liu, C.; Zeng, T.; Yuan, Z.; Hu, M.; Xiang, R.; Zhao, K.; Zhou, J.; Yang, S.; Wang, Y.; Meng, K.; Wang, H.; He, G.; Zhao, R.; Liu, J.; Huang, Y.; Pan, J.; Wang, J.; Chen, J.; Guo, F.; Dong, Y.; Xu, X.; Luo, D.; Gu, Y.; Liu, L.; Dong, Z.; Chen, L.
10.1101/2024.09.08.611790 — developmental biology — Posted on 2024-09-08
4226 Influence of vine decline disease on the amino acid metabolism of watermelon fruit
Santo, H.; Tadano, S.; Inokami, F.; Nishioka, T.; Konaka, T.; Sakata, M.; Morimoto, Y.; Akashi, K.
10.1101/2024.05.11.593714 — plant biology — Posted on 2024-09-08
4228 Changes in local mineral homeostasis facilitate the formation of benign and malignant testicular microcalcifications
Boisen, I. M.; Knudsen, N.; Nielsen, J. E.; Kooij, I.; Bagger, M.; Kaludjerovic, J.; O'Shaughnessy, P.; Andrews, P. W.; Ide, N.; Toft, B. G.; Juul, A.; mehmedbasic, A.; Joergensen, A.; Smith, L. B.; Norman, R.; Rajpert-De Meyts, E.; Lanske, B.; Blomberg Jensen, M.
10.1101/2020.06.25.171355 — molecular biology — Posted on 2024-09-08
4233 Mutagenesis Sensitivity Mapping of HumanEnhancers In Vivo
Kosicki, M.; Zhang, B.; Pampari, A.; Akiyama, J. A.; Playzer-Frick, I.; Novak, C. S.; Tran, S.; Zhu, Y.; Kato, M.; Hunter, R. D.; von Maydell, K.; Barton, S.; Beckman, E.; Kundaje, A.; Dickel, D. E.; Visel, A.; Pennacchio, L. A.
10.1101/2024.09.06.611737 — genomics — Posted on 2024-09-08
4236 MIP3α-RelMtb intranasal DNA vaccination induces reactive T-cell infiltration into the lungs in mice and macaques
Gordy, J. T.; Zheng, J. J.; Maxwell, A. R.; Taylor, A. D.; Karanika, S.; Bates, R. E.; Ton, H.; Meza, J.; Li, Y.; Zhang, J.; Karakousis, P. C.; Markham, R. B.
10.1101/2024.09.04.611263 — immunology — Posted on 2024-09-08
4238 Molecular and spatiotemporal characterization of cells in murine atherosclerotic plaques
Hou, P.; Liu, Z.; Fang, J.; Wang, Z.; Liu, S.; Wang, S.; Li, P.; Melino, G.; Shi, Y.; Shao, C.
10.1101/2024.09.04.611323 — pathology — Posted on 2024-09-08
4241 MYC plus class IIa HDAC inhibition potentiates mitochondrial dysfunction in non-small cell lung cancer
Park, J.; Chen, Y.-Y.; Cao, J. J.; An, J.; Yen, R.-W. C.; Outen, J. D.; Baylin, S. B.; Topper, M. J.
10.1101/2024.09.04.610116 — cancer biology — Posted on 2024-09-08
4242 Cell identity revealed by precise cell cycle state mapping links data modalities
Alahmari, S.; Schultz, A.; Albrecht, J.; Tagal, V.; Siddiqui, Z.; Prabhakaran, S.; El Naqa, I.; Anderson, A.; Heiser, L.; Andor, N.
10.1101/2024.09.04.610488 — bioinformatics — Posted on 2024-09-08
4244 Machine Learning Driven Optimization for High Precision Cellular Droplet Bioprinting
Shin, J.; Kang, M.; Hyun, K.; Li, Z.; Kumar, H.; Kim, K.; Park, S. S.; Kim, K.
10.1101/2024.09.04.611131 — bioengineering — Posted on 2024-09-08
4247 Enhancer activation from transposable elements in extrachromosomal DNA
Kraft, K.; Murphy, S. E.; Jones, M. G.; Shi, Q.; Bhargava-Shah, A.; Luong, C.; Hung, K. L.; He, B. J.; Li, R.; Park, S. K.; Weiser, N. E.; Luebeck, J.; Bafna, V.; Boeke, J. D.; Mischel, P. S.; Boettiger, A. N.; Chang, H. Y.
10.1101/2024.09.04.611262 — genetics — Posted on 2024-09-08
4249 Sex-specific chemosensory gene expression in the whitelined sphinx moth (Lepidoptera: Hyles lineata) suggests a role for odorant-binding proteins in host plant choice
Godfrey, R. K.; Auletta, A.; Cheung, E.; Harper, R. M.; Kates, K.; Kawahara, A. Y.; Li, Y.; Mercado, C.; Miguelena, F.; Pickett, G.; DiGennaro, P.
10.1101/2024.09.04.611314 — evolutionary biology — Posted on 2024-09-08
4251 The antimicrobial potential of traditional remedies of Indigenous Peoples from Canada against MRSA planktonic and biofilm bacteria in wound-infection mimetic conditions
Rieger, C. D.; Soliman, A. M.; Kaplia, K.; Ghosh, N.; Lopez, A. C.; Venkatesan, S. A.; Flores, A. G. G.; Belin, M. A. F.; Allen, F.; Reynolds, M.; McKenna, B.; Lavallee, H.; Weenie, A.; Favel, T.; Gendron, F.; Ziffle, V. E.; El-Halfawy, O. M.
10.1101/2024.09.08.611890 — microbiology — Posted on 2024-09-08
4252 A type 1 immune-stromal cell network mediates disease tolerance and barrier protection against intestinal infection
Westfall, S.; Gentile, M. E.; Olsen, T. M.; Karo-Atar, D.; Bogza, A.; Roestel, F.; Pardy, R.; Mandato, G.; Fontes, G.; Herbert, D.; Melichar, H. J.; Abadie, V.; Richer, M.; Vinh, D. C.; Koenig, J. F.; Harrison, O. J.; Divangahi, M. J.; Weis, S.; Gregorieff, A.; King, I. L.
10.1101/2024.09.04.611190 — immunology — Posted on 2024-09-08
4254 Putting computational models of immunity to the test - an invited challenge to predict B. pertussis vaccination outcomes
Shinde, P.; Willemsen, L.; Anderson, M.; Aoki, M.; Basu, S.; Burel, J. G.; Cheng, P.; Dastidar, S. G.; Dunleavy, A.; Einav, T.; Forschmiedt, J.; Fourati, S.; Garcia, J.; Gibson, W.; Greenbaum, J. A.; Guan, L.; Guan, W.; Gygi, J. P.; Ha, B.; Hou, J.; Hsiao, J.; Huang, Y.; Jansen, R.; Kakoty, B.; Kang, Z.; Kobie, J. J.; Kojima, M.; Konstorum, A.; Lee, J.; Lewis, S. A.; Li, A.; Lock, E. F.; Mahita, J.; Mendes, M.; Meng, H.; Neher, A.; Nili, S.; Orfield, S.; Overton, J.; Pai, N.; Parker, C.; Qian, B.; Rasmussen, M.; Reyna, J.; Richardson, E.; Safo, S.; Sorenson, J.; Srinivasan, A.; Thrupp, N.; Tip
10.1101/2024.09.04.611290 — immunology — Posted on 2024-09-08
4256 ATP Regeneration from Pyruvate in the PURE System
Yadav, S.; Perkins, A. J. P.; Liyanagedera, S. B. W.; Bougas, A.; Laohakunakorn, N.
10.1101/2024.09.06.611674 — synthetic biology — Posted on 2024-09-08
4257 Discordance in acute gastrointestinal toxicity between synchrotron-based proton and linac-based electron ultra-high dose rate irradiation
Liu, K.; Titt, U.; Esplen, N. M.; Connell, L.; Konradsson, E. K.; Yang, M.; Wang, X.; Takaoka, T.; Li, Z.; Koong, A. C.; Mitra, D.; Mohan, R.; Loo, B. W.; Lin, S. H.; Schueler, E.
10.1101/2024.09.04.611307 — cancer biology — Posted on 2024-09-08
4258 AI-enabled Alkaline-resistant Evolution of Protein to Apply in Mass Production
Kang, L.; Wu, B.; Zhou, B.; Tan, P.; Kang, Y.; Yan, Y.; Zong, Y.; Li, S.; Liu, Z.; Hong, L.
10.1101/2024.09.04.611192 — bioinformatics — Posted on 2024-09-08
4259 Supramolecular Enzyme-Peptide Gels for Localized Therapeutic Biocatalysis
Fuchs, M.; Seroski, D. T.; Soto Morales, B.; Melgar, L.; Scibilio, G.; Ziegler, A.; Liu, R.; Keselowsky, B. G.; Hudalla, G. A.
10.1101/2024.09.06.611628 — bioengineering — Posted on 2024-09-08
4260 Loss of the APP regulator RHBDL4 preserves memory in an Alzheimer's disease mouse model.
Penalva, Y. C. M.; Paschkowsky, S.; Yang, J.; Recinto, S. J.; Cinkorpumin, J.; Ruelas Hernandez, M.; Xiao, B.; Nitu, A.; Wu, H. Y.-L.; Munter, H. M.; Michalski, B.; Fahnestock, M.; Pastor, W. A.; Bennett, D. A.; Munter, L. M.
10.1101/2024.02.22.579698 — animal behavior and cognition — Posted on 2024-09-08
4263 Correlated spontaneous activity sets up multi-sensory integration in the developing higher-order cortex
Dwulet, J. M.; Zabouri, N.; Kirchner, J. H.; Wosniack, M. E.; Raspanti, A.; Kong, D.; Houwen, G. J.; Maldonado, P. P.; Lohmann, C.; Gjorgjieva, J.
10.1101/2024.07.19.603239 — neuroscience — Posted on 2024-09-08
4265 Single-molecule magnetic tweezers reveals that TAV2b-derived peptides underwind and stabilize double-stranded RNA
Rashid, Z. M.; Quack, S.; Klein, M.; Smitskamp, Q.; America, P.; Albers, M.; Paulus, J.; Grossmann, T.; Dulin, D.
10.1101/2024.09.05.611413 — biophysics — Posted on 2024-09-08
4266 Deep mutational scanning of the human insulin receptor ectodomain to inform precision therapy for insulin resistance
Aslanzadeh, V.; Brierley, G. V.; Kumar, R.; Cubuk, H.; Vigouroux, C.; Matreyek, K. A.; Kudla, G.; Semple, R. K.
10.1101/2024.09.07.611782 — genetics — Posted on 2024-09-08
4267 Pcbp1 constrains Oct4 expression in the context of pluripotency
Bakhmet, E. I.; Zinovyeva, A. S.; Kuzmin, A. A.; Smirnova, D. V.; Gordeev, M. N.; Petrenko, E. E.; Aksenov, N. D.; Tomilin, A. N.
10.1101/2024.09.07.611681 — cell biology — Posted on 2024-09-08
4268 3D nanoscale architecture of the respiratory epithelium reveals motile cilia-rootlets-mitochondria axis of communication
Vijayakumaran, A.; Godbehere, C.; Abuammar, A.; Breusegem, S. Y.; Hurst, L. R.; Morone, N.; Llodra, J.; Dalbay, M. T.; Tanvir, N. M.; MacLellan-Gibson, K.; O'Callaghan, C.; Lorentzen, E.; CellMap Project Team, ; FIB-SEM Technology, ; Murray, A.; Narayan, K.; Mennella, V.
10.1101/2024.09.08.611854 — cell biology — Posted on 2024-09-08
4269 Bioactivity Analysis of Secondary Metabolites from Actinomycetes' Isolated from Coastal Sediments
Shubhro, K.; Rimi, A. A.; Islam, M. E.; Islam, K. D.; Billah, M. M.; Mia, M.; Rahman, S. M.
10.1101/2024.09.08.611773 — microbiology — Posted on 2024-09-08
4270 TGFβ primes alveolar-like macrophages to induce type I IFN following TLR2 activation
Thomas, S. M.; Ankley, L. M.; Conner, K. N.; Rapp, A. W.; McGee, A. P.; LeSage, F.; Tanner, C. D.; Vielma, T. E.; Scheeres, E. C.; Obar, J. J.; Olive, A. J.
10.1101/2024.09.04.611226 — immunology — Posted on 2024-09-08
4275 Feather keratin in Pavo cristatus: A tentative structure
Russ, P.; Kirchner, H. O. K.; Peterlik, H.; Weiss, I. M.
10.1101/2024.09.08.611866 — biophysics — Posted on 2024-09-08
4278 Templated trimerization of the phage L decoration protein on capsids
Woodbury, B. M.; Newcomer, R. L.; Alexandrescu, A. T.; Teschke, C. M.
10.1101/2024.09.08.611893 — biochemistry — Posted on 2024-09-08
4282 Mis-regulation of GSK-3β causes axonal microtubule curling through Shot and Tau
Voelzmann, A.; Nuhu-Soso, L.; Roof, A.; Patel, S.; Bennett, H.; Adamson, A. D.; Bentley, M.; Evans, G. J. O.; Hahn, I.
10.1101/2024.09.08.611864 — cell biology — Posted on 2024-09-08
4285 Limited O-specific polysaccharide (OSP)-specific functional antibody responses in young children with Shigella infection in Bangladesh
Bernshtein, B.; Zhiteneva, J. A.; Janardhanan, J.; Wagh, C.; Kelly, M.; Verma, S.; Jung, W.; Basher, S. R.; Amin, M. A.; Mahamud, S.; Rajib, N. H.; Chowdhury, F.; Khan, A. I.; Charles, R. C.; Xu, P.; Kovac, P.; Chakraborty, S.; Kaminski, R. W.; Alter, G.; Bhuiyan, T. R.; Qadri, F.; Ryan, E. T.
10.1101/2024.09.04.611236 — immunology — Posted on 2024-09-08
4290 Aquavert: Imaging and Microfluidics for Vertical Swimming of Microorganisms
Obenshain, H. B.; Zarate, I.; Hedman-Manzano, O.; Goderich, J.; Lee, S.; Lopez, B. A.; Varela, E.; Suh, G.-Y. K.; Pace, D. A.; Ahrar, S.
10.1101/2024.09.07.611807 — biophysics — Posted on 2024-09-08
4295 Calibration of FRET-based biosensors using multiplexed biosensor barcoding
Wu, J.-W.; Yang, J.-M.; Chen, C.-C.; Au, G.; Wang, S.; Chern, G.-W.; Huang, C.-H.
10.1101/2024.09.04.610346 — biophysics — Posted on 2024-09-08
4305 Humidity as a zeitgeber for circadian entrainment of insect systems
Chen, S.-C.; Goodhart, G.; Eaton, D.; Catlett, N.; Cady, T.; Tran, H.; Lutz, L. E.; Wang, L.; Girard, E.; Savino, J.; Perry, J.; Hall, L.; Bidiwala, A.; Tarter, E.; Tompkin, J.; Greene, N.; Benoit, J.
10.1101/2024.09.04.611265 — physiology — Posted on 2024-09-08
4308 Systemic in utero gene editing as a treatment for cystic fibrosis
Ricciardi, A. S.; Barone, C.; Putman, R.; Quijano, E.; Gupta, A.; Nguyen, R.; Mandl, H.; Piotrowski-Daspit, A. S.; Lopez-Giraldez, F.; Luks, V.; Freedman-Weiss, M. R.; Farrelly, J. S.; Ahle, S.; Glazer, P. M.; Saltzman, W. M.; Stitelman, D. H.; Egan, M. E.
10.1101/2024.09.04.611031 — bioengineering — Posted on 2024-09-08
4309 Structural proteomics defines a sequential priming mechanism for the progesterone receptor
Mann, M. D.; Wang, M.; Ferreon, J. C.; Suess, M. P.; Jain, A.; Malovannaya, A.; Pascal, B. D.; Kumar, R.; Edwards, D. P.; GRIFFIN, P. R.
10.1101/2024.09.06.611729 — biochemistry — Posted on 2024-09-08
4313 Selective attention and sensitivity to auditory disturbances in a virtually-real Classroom: Comparison of adults with and without AD(H)D
Levy, O.; Libman Hackmon, S.; Zvilichovsky, Y.; Korisky, A.; Bidet-Caulet, A.; Schweitzer, J. B.; Zion Golumbic, E.
10.1101/2024.04.17.590012 — neuroscience — Posted on 2024-09-08
4316 Altered cellular metabolic pathway and epithelial cell maturation induced by MYO5B defects are partially reversible by LPAR5 activation
Momoh, M.; Rathan-Kumar, S.; Burman, A.; Brown, M. E.; Adeniran, F.; Ramos, C.; Goldenring, J. R.; Roland, J. T.; Kaji, I.
10.1101/2024.09.03.610579 — physiology — Posted on 2024-09-08
4318 Bacterial transcriptional repressor NrdR - a flexiblemultifactorial nucleotide sensor
Rozman Grinberg, I.; Bimai, O.; Shahid, S.; Philipp, L.; Martinez-Carranza, M.; Banerjee, I.; Lundin, D.; Stenmark, P.; Sjoberg, B.-M.; Logan, D. T.
10.1101/2024.09.04.609659 — biophysics — Posted on 2024-09-08
4322 A Digital Microfluidic Platform for the Microscale Production of Functional Immune Cell Therapies
Little, S. R.; Rahbari, N.; Hajiaghayi, M.; Gholizadeh, F.; Cloarec-Ung, F.-M.; Phillips, J.; Sinha, H.; Hirukawa, A.; Knapp, D. J.; Darlington, P. J.; Shih, S. C.
10.1101/2024.09.03.611092 — bioengineering — Posted on 2024-09-08
4324 Membrane vesicles can contribute to cellulose degradation by Teredinibacter turnerae, a cultivable intracellular endosymbiont of shipworms
Gasser, M. T.; Liu, A.; Altamia, M. A.; Bresinger, B.; Brewer, S. L.; Flatau, R.; Hancock, E.; Preheim, S. P.; Filone, C. M.; Distel, D. L.
10.1101/2024.03.27.587001 — microbiology — Posted on 2024-09-08
4325 Pupil self-regulation modulates markers of cortical excitability and cortical arousal
Weijs, M. L.; Missura, S.; Potok-Szybinska, W.; Bächinger, M.; Badii, B.; Carro-Dominguez, M.; Wenderoth, N.; Meissner, S. N.
10.1101/2024.09.04.611153 — neuroscience — Posted on 2024-09-08
4327 Mouse Brain Extractor: Brain segmentation of mouse MRI using global positional encoding and SwinUNETR
Kim, Y.; Hrncir, H.; Meyer, C. E.; Tabbaa, M.; Moats, R. A.; Levitt, P.; Harris, N. G.; MacKenzie-Graham, A. J.; Shattuck, D. W.
10.1101/2024.09.03.611106 — neuroscience — Posted on 2024-09-08
4332 Resolving Symbiodiniaceae diversity across coral microhabitats and reef niches
Million, W.; Voolstra, C. R.; Perna, G.; Puntin, G.; Rowe, K.; Ziegler, M.
10.1101/2024.09.06.611593 — systems biology — Posted on 2024-09-08
4333 Frame-shift mutation of InCO might cause early flowering of Japanese morning glory and might have contributed to northward expansion
Katsuyama, H.; Ito, T.; Ezura, K.; Haque, E.; Hoshino, A.; Nitasaka, E.; Ono, M.; Sato, S.; Isobe, S.; Fukuoka, H.; Watanabe, N.; Kuboyama, T.
10.1101/2024.09.05.611556 — plant biology — Posted on 2024-09-08
4334 Target protein identification in live cells and organisms with a non-diffusive proximity tagging system
Sun, Y.; Li, C.; Deng, X.; Li, W.; Deng, X.; Ge, W.; Shi, M.; Guo, Y.; Yu, Y. V.; Zhou, H.-b.; Jin, Y. N.
10.1101/2024.09.06.611731 — pharmacology and toxicology — Posted on 2024-09-08
4336 Two-photon driven photoprotection mechanism in echinenone-functionalized Orange Carotenoid Protein
Nizinski, S.; Hartmann, E.; Shoeman, R. L.; Wilson, A.; Reinstein, J.; Kirilovsky, D.; Sliwa, M.; Burdzinski, G.; Schlichting, I.
10.1101/2024.09.06.611699 — biophysics — Posted on 2024-09-08
4338 Deep Generative Optimization of mRNA Codon Sequences for Enhanced Protein Production and Therapeutic Efficacy
Li, Y.; Wang, F.; Yang, J.; Han, Z.; Chen, L.; Jiang, W.; Zhou, H.; Li, T.; Tang, Z.; Deng, J.; He, X.; Zha, G.; Hu, J.; Hu, Y.; Wu, L.; Zhan, C.; Sun, C.; He, Y.; Xie, Z.
10.1101/2024.09.06.611590 — bioinformatics — Posted on 2024-09-08
4340 Exploring cellular changes in ruptured human quadriceps tendons at single-cell resolution
Mimpen, J. Y.; Baldwin, M. J.; Paul, C.; Ramos-Mucci, L.; Kurjan, A.; Cohen, C. J.; Sharma, S.; Chevalier Florquin, M. S. N.; Hulley, P. A.; McMaster, J.; Titchener, A.; Martin, A.; Costa, M. L.; Gwilym, S. E.; Cribbs, A. P.; Snelling, S. J. B.
10.1101/2024.09.06.611599 — genomics — Posted on 2024-09-08
4341 Integrating Phenomic Selection Using Single-Kernel Near-Infrared Spectroscopy and Genomic Selection for Corn Breeding Improvement
Prado Graciano, R.; Antonio Peixoto, M.; Leach, K. A.; Suzuki, N.; Gustin, J.; Settles, A. M.; Armstrong, P. R.; Resende, M. F.
10.1101/2024.09.07.611678 — genetics — Posted on 2024-09-08
4344 Enhancing HBV-specific T cell responses through a combination of epigenetic modulation and immune checkpoint inhibition
Urbanek-Quaing, M.; Chou, Y.-H.; Gupta, M. K.; Steppich, K.; Bremer, B.; Schmaus, H.; Deterding, K.; Maasoumy, B.; Wedemeyer, H.; Xu, C.-J.; Kraft, A. R. M.; Cornberg, M.
10.1101/2024.09.06.611632 — immunology — Posted on 2024-09-08
4349 Genome composition predicts physiological response to environmental change in polyploid salamanders
Burger, I.; Itgen, M.; Tan, L.; Woodward, P.; Rivas, L.; Hunt, T.; Ready, H.; Martin Geronimo, X.; Denton, R.; Riddell, E.
10.1101/2024.09.06.611688 — physiology — Posted on 2024-09-08
4351 Coat protein of TCV suppresses RNA decay via ubiquitination and autophagy pathways to facilitate viral infection
Wu, K.; Xie, Q.; Liu, X.; Fu, Y.; Li, S.; Yu, X.; Li, W.; Zhao, P.; Ren, Y.; Ruan, M. B.; Zhang, X.
10.1101/2024.09.05.611546 — pathology — Posted on 2024-09-08
4353 NetMedPy: A Python package for Large-Scale Network Medicine Screening
Aldana, A.; Sebek, M.; Ispirova, G.; Dorantes-Gilardi, R.; Barabasi, A.-L.; Loscalzo, J.; Menichetti, G.
10.1101/2024.09.05.611537 — bioinformatics — Posted on 2024-09-08
4357 Sub-3 A resolution protein structure determination by single-particle cryo-EM at 100 keV
Karia, D.; Koh, A. F.; Yang, W.; Cushing, V. I.; Basanta, B.; Mihaylov, D. B.; Khavnekar, S.; Vyroubal, O.; Malinsky, M.; Shanel, O.; Dolezal, V.; Plitzko, J. M.; Yu, L.; Lander, G. C.; Aricescu, A. R. C.; Greber, B. J.; Kotecha, A.
10.1101/2024.09.05.611417 — biophysics — Posted on 2024-09-08
4358 Legume genome structures and histories inferred from Cercis canadensis and Chamaecrista fasciculata genomes
Lee, H.-o.; Stai, J. S.; Xu, Q.; Hewavithana, T.; Batra, R.; Liu, A.; Jordan, B. D.; Walstead, R.; Jenkins, J. W.; Williams, M.; Webber, j.; Grimwood, J.; Lovell, J. T.; Bruna, T.; Shu, S.; Keymanesh, K.; Eichenberger, J.; Schmutz, J.; Goodstein, D. M.; Barry, K. W.; Sankoff, D.; Jin, L.; Leebens-Mack, J.; Cannon, S. B.
10.1101/2024.09.03.611065 — genomics — Posted on 2024-09-08
4359 Typical development of synaptic and neuronal properties can proceed without microglia
O'Keeffe, M.; Booker, S.; Walsh, D.; Li, M.; Henley, C.; Simoes de Oliveira, L.; Liu, M.; Wang, X.; Banqueri-Lopez, M.; Ridley, K.; Dissanyake, K.; Martinez-Gonzales, C.; Craigie, K.; Vasoya, D.; Leah, T.; He, X.; Hume, D. A.; Duguid, I.; Nolan, M.; Qiu, J.; Wyllie, D. J.; Dando, O.; Gonzales-Sulsar, A.; Gan, J.; Pridans, C.; Kind, P. C.; Hardingham, G. E.
10.1101/2024.09.06.611614 — neuroscience — Posted on 2024-09-08
4362 Modeling Cortical Versus Hippocampal Network Dysfunction in a Human Brain Assembloid Model of Epilepsy and Intellectual Disability
McCrimmon, C. M.; Toker, D.; Pahos, M.; Lozano, K.; Lin, J. J.; Parent, J.; Tidball, A.; Zheng, J.; Molnar, L.; Mody, I.; Novitch, B. G.; Samarasinghe, R. A.
10.1101/2024.09.07.611739 — neuroscience — Posted on 2024-09-08
4363 Brain-wide mapping of oligodendrocyte organization and oligodendrogenesis across the murine lifespan
Xu, Y. K. T.; Bush, A.; Musheyev, E.; Kim, A. A.; Zhang, S.; Eugenin von Bernhardi, J.; Sulam, J.; Bergles, D. E.
10.1101/2024.09.06.611254 — neuroscience — Posted on 2024-09-08
4364 Single-nucleus multi-omics identifies shared and distinct pathways in Pick's and Alzheimer's disease
Shi, Z.; Das, S.; Morabito, S.; Miyoshi, E.; Stocksdale, J.; Emerson, N.; Srinivasan, S. S.; Shahin, A.; Rahimzadeh, N.; Cao, Z.; Silva, J.; Castaneda, A. A.; Head, E.; Thompson, L.; Swarup, V.
10.1101/2024.09.06.611761 — neuroscience — Posted on 2024-09-08
4365 Caveolin-1 and mechanical stress control the release of a pro-metastatic subpopulation of small extracellular vesicles
Saquel, C.; Gracia, C.; Viaris de Lesegno, C.; Verweij, F.; Urena-Martin, C.; Raposo, G.; Lamaze, C.
10.1101/2024.09.05.611225 — cancer biology — Posted on 2024-09-08
4366 Grb2 Phosphorylation Antagonizes EGFR-driven Ras Activation by Interfering with Condensate Assembly
Phan, H. T.; Lin, C.-W.; Stinger, B. L.; DeGrandchamp, J. B.; Lew, L. J. N.; Huang, S. J.; Groves, J. T.
10.1101/2024.09.05.611544 — biophysics — Posted on 2024-09-07
4368 New loci and candidate genes in spring two-rowed barley detected through meta-analysis of a field trial European network
Montardit-Tarda, F.; Casas, A. M.; Thomas, W.; Schnaithmann, F.; Sharma, R.; Shaaf, S.; Campoli, C.; Russell, J.; Ramsay, L.; Delbono, S.; Jääskeläinen, M.; Paul, M.; Stoddard, F.; Visioni, A.; Flavell, A. J.; Pillen, K.; Kilian, B.; Graner, A.; Rossini, L.; Waugh, R.; Cattivelli, L.; Schulman, A. H.; Tondelli, A.; Igartua, E.
10.1101/2024.09.04.611234 — genetics — Posted on 2024-09-07
4370 Connecting crowns: Analyzing morphological covariation in the modern human postcanine dentition
Simkova, P. G.; Krenn, V. A.; Fornai, C.; Wurm, L.; Halasz, V.; Lidinsky, D.; Weber, G. W.
10.1101/2024.09.05.611460 — evolutionary biology — Posted on 2024-09-08
4372 Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells
McCreery, K. P.; Stubb, A.; Stephens, R.; Fursova, N. A.; Cook, A.; Kruse, K.; Michelbach, A.; Biggs, L. C.; Keikhosravi, A.; Nykanen, S.; Hyden-Granskog, C.; Zou, J.; Lackmann, J.-W.; Niessen, C. M.; Vuoristo, S.; Miroshnikova, Y. A.; Wickstrom, S. A.
10.1101/2024.09.07.611779 — cell biology — Posted on 2024-09-07
4373 Neural Representations of Extrasystoles: A Predictive Coding Perspective
Reinfeld, P.; Steinfath, T. P.; Ku, P.-H.; Nikulin, V.; Neumann, J.; Villringer, A.
10.1101/2024.09.06.610728 — neuroscience — Posted on 2024-09-07
4377 An antibiotic that mediates immune destruction of senescent cancer cells
Casagrande Raffi, G.; Chen, J.; Feng, X.; Chen, Z.; Lieftink, C.; Deng, S.; Mo, J.; Zeng, C.; Steur, M.; Wang, J.; Bleijerveld, O.; Hoekman, L.; van der Wel, N.; Wang, F.; Beijersbergen, R.; Zheng, J.; Bernards, R. R.; Wang, L.
10.1101/2024.09.05.611241 — cancer biology — Posted on 2024-09-07
4379 Multiscale topological analysis of kinetoplast DNA via high-resolution AFM
Diggines, B.; Whittle, S.; Yadav, I.; Holmes, E. P.; Rollins, D. E.; Catley, T. E.; Doyle, P. S.; Pyne, A. L. B.
10.1101/2024.09.06.611637 — biophysics — Posted on 2024-09-07
4383 The Protein Design Archive (PDA): insights from 40 years of protein design
Chronowska, M.; Stam, M. J.; Woolfson, D. N.; Di Costanzo, L. F.; Wood, C. W.
10.1101/2024.09.05.611465 — bioinformatics — Posted on 2024-09-07
4384 Metapipeline-DNA: A Comprehensive Germline & Somatic Genomics Nextflow Pipeline
Patel, Y.; Zhu, C.; Yamaguchi, T. N.; Wang, N.; Wiltsie, N.; Gonzalez, A.; Winata, H.; Zeltser, N.; Pan, Y.; Mootor, M. F. E.; Sanders, T.; Kandoth, C.; Fitz-Gibbon, S. T.; Livingstone, J.; Liu, L. Y.; Carlin, B.; Holmes, A.; Oh, J.; Sahrmann, J.; Tao, S.; Eng, S.; Hugh-White, R.; Pashminehazar, K.; Park, A.; Beshlikyan, A.; Jordan, M.; Wu, S.; Tian, M.; Arbet, J.; Neilsen, B.; Bugh, Y. Z.; Kim, G.; Salmingo, J.; Zhang, W.; Haas, R.; Anand, A.; Hwang, E.; Neiman-Golden, A.; Steinberg, P.; Zhao, W.; Anand, P.; Tsai, B. L.; Boutros, P. C.
10.1101/2024.09.04.611267 — bioinformatics — Posted on 2024-09-07
4385 In Vivo Optical Clearing of Mammalian Brain
Talei Franzesi, G.; Gupta, I.; Hu, M.; Piatkveich, K.; Yildirim, M.; Zhao, J.-P.; Eom, M.; Han, S.; Park, D.; Andaraarachchi, H.; Li, Z.; Greenhagen, J.; Islam, A. M.; Vashishtha, P.; Yaqoob, Z.; Pak, N.; Wissner-Gross, A. D.; Martin-Alarcon, D.; Veinot, J.; So, P. T.; Kortshagen, U.; Yoon, Y.-G.; Sur, M.; Boyden, E. S.
10.1101/2024.09.05.611421 — bioengineering — Posted on 2024-09-07
4387 Human and bats genome robustness under COSMIC mutational signatures
Song, J.-H.; Zeng, Y.; Davalos, L. M.; MacCarthy, T.; Larijani, M.; Damaghi, M.
10.1101/2024.09.05.611453 — genomics — Posted on 2024-09-07
4388 Telomere-to-telomere African wild rice (Oryza longistaminata) reference genome reveals segmental and structural variation
Guang, X.; Yang, J.; Zhang, S.; Guo, F.; Li, L.; Lian, X.; Zeng, T.; Cai, C.; Liu, F.; Li, Z.; Hu, Y.; Fang, D.; He, W.; Sahu, S. K.; Li, W.; Lu, H.; Li, Y.; Liu, H.; Xu, X.; Guang, Y.; Hu, F.; Dong, Y.; Wei, T.
10.1101/2024.09.05.611405 — genomics — Posted on 2024-09-07
4389 MHC heterozygosity may increase subordinate but not alpha male siring success in white-faced capuchin monkeys (Cebus imitator)
Buckner, J. C.; Jack, K. M.; Buehler, M.; Melin, A. D.; Schoof, V. A.; Wikberg, E.; Chaves, S.; Fedigan, L. M.; Lynch, J. W.
10.1101/2024.09.04.611202 — evolutionary biology — Posted on 2024-09-07
4390 The Interplay of Resource Availability and Parent Foraging Strategies on Juvenile Sparrow Individual Specialization
Ricote, N.; Weinberger, C.; Ramirez-Otarola, N.; Bustamante, S.; Malaga, M. L.; Barcelo, G.; Sabat, P.; Newsome, S. D.; Maldonado, K.
10.1101/2024.02.29.582146 — ecology — Posted on 2024-09-07
4392 Macrophage-intrinsic MDA5-IRF5 axis drives HIV-1 icRNA-induced inflammatory responses
Ramaswamy, S.; Akiyama, H.; Berrigan, J.; Quinones, A.; Olson, A.; Chen, Y.; Lang, Y. M.; Henderson, A. J.; Asundi, A.; Sagar, M.; Gummuluru, S.
10.1101/2024.09.06.611547 — microbiology — Posted on 2024-09-07
4393 Virus-like particle-based vaccines targeting the Anopheles mosquito salivary protein, TRIO
Francian, A.; Flores-Garcia, Y.; Powell, J. R.; Petrovsky, N.; Zavala, F.; Chackerian, B.
10.1101/2024.09.05.611467 — immunology — Posted on 2024-09-07
4394 Antigen-specificity of clonally-enriched CD8+ T cells in multiple sclerosis
Mittl, K.; Hayashi, F.; Dandekar, R.; Schubert, R. D.; Gerdts, J.; Oshiro, L.; Loudermilk, R.; Greenfield, A. L.; Augusto, D. G.; Ramesh, A.; Tran, E.; Koshal, K.; Kizer, K.; Dreux, J.; Cagalingan, A.; Schustek, F.; Flood, L.; Moore, T.; Kirkemo, L. L.; Cooper, T.; Harms, M.; Gomez, R.; University of California, San Francisco MS-EPIC Team, ; Sibener, L.; Cree, B. A. C.; Hauser, S. L.; Hollenbach, J. A.; Gee, M.; Wilson, M. R.; Zamvil, S.; Sabatino, J. J.
10.1101/2024.09.07.611010 — immunology — Posted on 2024-09-07
4395 Gradients of Recognition Molecules Shape Synaptic Specificity of a Visuomotor Transformation
Dombrovski, M.; Zang, Y.; Frighetto, G.; Vaccari, A.; Jang, H.; Mirshahidi, P. S.; Xie, F.; Sanfilippo, P.; Hina, B. W.; Rehan, A.; Hussein, R. H.; Mirshahidi, P. S.; Lee, C.; Frye, M. A.; von Reyn, C. R.; Kurmangaliyev, Y. Z.; Card, G. M.; Zipursky, S. L.
10.1101/2024.09.04.610846 — neuroscience — Posted on 2024-09-07
4396 When Do Visual Category Representations Emerge in Infants' Brains?
Yan, X.; Tung, S.; Fascendini, B.; Chen, Y. D.; Norcia, A. M.; Grill-Spector, K.
10.1101/2023.05.11.539934 — neuroscience — Posted on 2024-09-07
4397 A generalizable normative deep autoencoder for brain morphological anomaly detection: application to the multi-site StratiBip dataset on bipolar disorder in an external validation framework.
Sampaio, I. W.; Tassi, E.; Bellani, M.; Benedetti, F.; Nenadic, I.; Phillips, M.; Piras, F.; Yatham, L.; Bianchi, A. M.; Brambilla, P.; Maggioni, E.
10.1101/2024.09.04.611239 — neuroscience — Posted on 2024-09-07
4399 Placental Network Differences Among Obstetric Syndromes Identified With An Integrated Multiomics Approach
Piekos, S. N.; Barak, O.; Baumgartner, A.; Chu, T.; Parks, W. T.; Hadlock, J.; Hood, L.; Price, N.; Sadovsky, Y.
10.1101/2024.09.03.611067 — systems biology — Posted on 2024-09-07
4402 Expression, purification, and characterization of diacylated Lipo-YcjN from Escherichia coli
Trevino, M. A.; Amankwah, K.; Fernandez, D.; Weston, S.; Stewart, C. J.; Morales Gallardo, J.; Shahgholi, M.; Sharaf, N. G.
10.1101/2024.09.05.611266 — biophysics — Posted on 2024-09-07
4407 A Computational Framework to Optimize the Mechanical Behavior of Synthetic Vascular Grafts
Jiang, D.; Robinson, A. J.; Nkansah, A.; Leung, J.; Guo, L.; Maas, S. A.; Weiss, J. A.; Cosgriff-Hernandez, E. M.; Timmins, L. H.
10.1101/2024.09.05.608688 — bioengineering — Posted on 2024-09-07
4408 The flexible stalk domain of sTREM2 modulates its interactions with phospholipids in the brain
Saeb, D.; Lietzke, E. E.; Fuchs, D. I.; Aldrich, E. C.; Bruce, K. D.; Sprenger, K. G.
10.1101/2024.09.04.611223 — bioengineering — Posted on 2024-09-07
4411 Structural proteomics defines a sequential priming mechanism for the progesterone receptor
Mann, M. D.; Wang, M.; Ferreon, J. C.; Suess, M. P.; Jain, A.; Malovannaya, A.; Pascal, B. D.; Kumar, R.; Edwards, D. P.; GRIFFIN, P. R.
10.1101/2024.09.06.611729 — biochemistry — Posted on 2024-09-07
4413 Dynamics and determinants of the gut mobilome in early life
Fernandez-Pato, A.; Sinha, T.; Garmaeva, S.; Gulyaeva, A.; Kuzub, N.; Roux, S.; Fu, J.; Kurilshikov, A.; Zhernakova, A.
10.1101/2024.09.06.611692 — genomics — Posted on 2024-09-07
4414 Discovery of a new Phenuivirus species in Lachenalia plants reveals possible co-evolution between 5' and 3' RNA sequence motifs
Dekker, R. J.; de Leeuw, W. C.; van Olst, M.; Ensink, W. A.; van Leeuwen, S.; Breit, T. M.; Jonker, M. J.
10.1101/2024.09.04.611151 — genomics — Posted on 2024-09-07
4416 Mapping HIV-1 RNA Structure, Homodimers, Long-Range Interactions and persistent domains by HiCapR
Zhang, Y.; Han, J.; Dejian, X.; Shen, W.; Li, P.; Lau, J. Y.; Li, J.; Li, L.; Kudla, G.; Zhao, Z.
10.1101/2024.09.03.610837 — genomics — Posted on 2024-09-07
4422 Protein degradation by small tag artificial bacterial E3 ligase
Warming, S.; Liu, Z.; Tsai, M.-C.; Ghosh, S.; Lawrence, J.; Chu, S.; Bingol, B.
10.1101/2024.09.07.611797 — molecular biology — Posted on 2024-09-07
4423 Pentose Phosphate Pathway Protects E. coli from Antibiotic Lethality
Seregina, T.; Shakulov, R.; Shatalin, K.; Petrushanko, I.; Mitkevich, V.; Makarov, A.; Mironov, A.; Nudler, E.
10.1101/2024.09.07.611820 — microbiology — Posted on 2024-09-07
4424 Rational selection of TbpB variants elucidates a bivalent vaccine formulation with broad spectrum coverage against Neisseria gonorrhoeae
Fegan, J. E.; Islam, E. A.; Curran, D. M.; Ng, D.; Au, N.; Currie, E. G.; Zeppa, J.; Lam, J.; Schryvers, A. B.; Moraes, T. F.; Gray-Owen, S. D.
10.1101/2024.09.07.611798 — microbiology — Posted on 2024-09-07
4426 Multi-strain phage induced clearance of bacterial infections
Marchi, J.; Nguyen Ngoc Minh, C.; Debarbieux, L.; Weitz, J. S.
10.1101/2024.09.07.611814 — microbiology — Posted on 2024-09-07
4427 Cyanobacteria from marine oxygen deficient zones encode both form I and form II rubiscos
Jaffe, A. L.; Harrison, K.; Jain, N.; Taylor-Kearney, L. J.; Wang, R. Z.; Prywes, N.; Shih, P.; Young, J.; Rocap, G.; Dekas, A. E.
10.1101/2024.09.06.611767 — microbiology — Posted on 2024-09-07
4428 Mitochondrial Hyperactivity and Reactive Oxygen Species Drive Innate Immunity to the Yellow Fever Virus-17D Live-Attenuated Vaccine
Muccilli, S. G.; Schwarz, B.; Jessop, F.; Shannon, J. G.; Bohrnsen, E.; Shue, B.; Hong, S.-H.; Hsu, T.; Ashbrook, A. W.; Guarnieri, J. W.; Lack, J.; Wallace, D. C.; Bosio, C. M.; MacDonald, M. R.; Rice, C. M.; Yewdell, J. W.; Best, S. M.
10.1101/2024.09.04.611167 — immunology — Posted on 2024-09-07
4429 Therapeutic DNA Vaccine Targeting Mycobacterium tuberculosis Persisters Shortens Curative Tuberculosis Treatment
Karanika, S.; Wang, T.; Yilma, A.; Castillo, J. R.; Gordy, J. T.; Bailey, H.; Quijada, D.; Fessler, K.; Tasneen, R.; Salcido, E. M. R.; Harris, H.; Bates, R. E.; Ton, H.; Meza, J.; Li, Y.; Taylor, A. D.; Zhenq, J. J.; Zhang, J.; Peske, J. D.; Karantanos, T.; Maxwell, A. R.; Nuermberger, E.; Markham, R. B.; Karakousis, P. C.
10.1101/2024.09.03.611055 — immunology — Posted on 2024-09-07
4430 Identification of small molecule enhancers of NK cell tumoricidal activity via a tumor microenvironment-mimicking co-culture assay
Binici, A.; Hennes, E.; Koska, S.; Niemann, J.; Reich, A.; Pfaff, C.; Sievers, S.; Kahnt, A.; Thomas, D.; Ziegler, S.; Watzl, C.; Waldmann, H.
10.1101/2024.09.04.611205 — immunology — Posted on 2024-09-07
4433 Sex-Specific Roles of Hypocretin Receptor Signaling in CRF Neurons on Alcohol Drinking, Anxiety, and BNST Neuronal Excitability
Ma, Y.; Sardar, H.; Benabou, M. E.; Yu, A. C.; Morningstar, A. R.; Fajardo, R. N.; Kandil, I. F.; Rogers, E. T.; Vassalli, A.; Kauer, J. A.; Giardino, W. J.
10.1101/2024.09.07.609774 — neuroscience — Posted on 2024-09-07
4434 Astrocytic Regulation of Cocaine Locomotor Sensitization in EcoHIV Infected Mice
Xie, Q.; Dasari, R.; Namba, M. D.; Buck, L. A.; Side, C. M.; Park, K.; Jackson, J. G.; Barker, J. M.
10.1101/2024.09.04.611213 — neuroscience — Posted on 2024-09-07
4435 British Version of the Iowa Test of Consonant Perception
Guo, X.; Benzaquen, E.; Holmes, E.; Choi, I.; McMurray, B.; Bamiou, D.-E.; Berger, J. I.; Griffiths, T. D.
10.1101/2024.09.04.611204 — neuroscience — Posted on 2024-09-07
4436 Patch-leaving decisions and pupil-linked arousal systems
Marzecova, A.; Vernaillen, B.; Hoxhaj, D.; Kaiser, L. F.; Verguts, T.; Jocham, G.
10.1101/2024.09.06.611272 — neuroscience — Posted on 2024-09-07
4437 Tissue-specific and functional loci analysis of CASP14 gene in the sheep horn
Lu, X.; Zhang, G.; Yang, H.; Shan, M.; Zhang, X.; Wang, Y.; Bai, J.; Pan, Z.
10.1101/2024.09.03.611085 — zoology — Posted on 2024-09-07
4440 The proteomic landscape and temporal dynamics of mammalian gastruloid development
Garge, R. K.; Lynch, V.; Fields, R.; Casadei, S.; Best, S.; Stone, J.; Snyder, M.; McGann, C. D.; Shendure, J.; Starita, L. M.; Hamazaki, N.; Schweppe, D. K.
10.1101/2024.09.05.609098 — systems biology — Posted on 2024-09-07
4441 Neighbor sensing through rhizodeposits in sorghum affects plant physiology and productivity
Ben-Zeev, S.; Penn, A.; Lawrence-Paul, E. H.; Abrams, D. R.; Ben-Zeev, R.; Lowry, C.; Lasky, J.
10.1101/2024.09.04.611020 — plant biology — Posted on 2024-09-07
4443 Selective Agonism of Liver and Gut FXR Prevents Cholestasis and Intestinal Atrophy in Parenterally Fed Neonatal Pigs
Jiang, Y.; Fang, Z.; Guthrie, G.; Stoll, B.; Chacko, S.; Lin, S.; Hartmann, B.; Holst, J. J.; Dawson, H.; Pastor, J. J.; Ipharraguerre, I. R.; Burrin, D. G.
10.1101/2024.09.03.611073 — physiology — Posted on 2024-09-07
4445 Molecular glues that inhibit specific Zn2+-dependent DUB activity and inflammation
Chandler, F.; Reddy, P. A. N.; Bhutda, S.; Ross, R. L.; Walden, M.; Walker, K.; Di Donato, S.; Cassel, J. A.; Prakesch, M. A.; Aman, A.; Datti, A.; Campbell, L. J.; Foglizzo, M.; Bell, L.; Stein, D. N.; Ault, J. R.; Al-awar, R. S.; Calabrese, A. N.; Sicheri, F.; Del Galdo, F.; Salvino, J. M.; Greenberg, R. A.; Zeqiraj, E.
10.1101/2024.09.07.611787 — biochemistry — Posted on 2024-09-07
4447 H/ACA snoRNP guides ribosomal RNA subdomain folding in a satellite particle before joining the core 90S pre-ribosome
Fischer, P.; Thoms, M.; Lau, B.; Denk, T.; Kuvshinova, M.; Berninghausen, O.; Flemming, D.; Hurt, E.; Beckmann, R.
10.1101/2024.09.05.611419 — biochemistry — Posted on 2024-09-07
4450 Efficiently Constructing Complete Genomes with CycloneSEQ to Fill Gaps in Bacterial Draft Assemblies
Liang, H.; Wang, M.; Hu, T.; Wang, H.; He, W.; Ju, Y.; Guo, R.; Chen, J.; Guo, F.; Zeng, T.; Dong, Y.; Wang, B.; Liu, C.; Jin, X.; Zhang, W.; Zou, Y.; Xu, X.; Xiao, L.
10.1101/2024.09.05.611410 — genomics — Posted on 2024-09-07
4452 Community-wide interactions sustain life in geothermal spring habitats
Stephens, T. G.; Van Etten, J.; McDermott, T.; Christian, W.; Chaverra, M.; Gurney, J.; Lee, Y.; Kim, H.; Cho, C. H.; Chovancek, E.; Westhoff, P.; Otte, A.; Northen, T. R.; Bowen, B. P.; Louie, K. B.; Barry, K.; Grigoriev, I. V.; Mock, T.; Liu, S.-L.; Miyagishima, S.-y.; Yoshinaga, M.; Weber, A.; Yoon, H. S.; Bhattacharya, D.
10.1101/2024.09.03.611078 — evolutionary biology — Posted on 2024-09-07
4454 Human transferrin and lactoferrin cooperatively support Neisseria meningitidis colonization in the murine nasopharynx
Lee, I. S.; Fegan, J. E.; Currie, E. G.; Bojagora, A.; Leung, N. Y.; Rancourt, D.; Taha, M.-K.; Schryvers, A. B.; Gray-Owen, S.
10.1101/2024.09.07.611816 — microbiology — Posted on 2024-09-07
4455 C7-substituted Quinolines as Potent Inhibitors of AdeG Efflux Pumps in Acinetobacter baumannii
Zhu, Y.; Hind, C.; Al-Adhami, T.; Wand, M.; Clifford, M.; Sutton, J. M.; Rahman, K. M.
10.1101/2024.09.07.611778 — microbiology — Posted on 2024-09-07
4456 Multiplexing bacteriocin synthesis to kill and prevent antimicrobial resistance
Quintero-Yanes, A.; Petit, K.; Rodriguez-Villalobos, H.; Vande Capelle, H.; Masschelein, J.; Borrero del Pino, J.; Gabant, P.
10.1101/2024.09.06.611659 — synthetic biology — Posted on 2024-09-07
4458 Temperature Sensitive Glutamate Gating of AMPA-subtype iGluRs
Kumar Mondal, A.; Carrillo, E.; Jayaraman, V.; Twomey, E. C.
10.1101/2024.09.05.611422 — biophysics — Posted on 2024-09-07
4460 Pannexin 1 and Pannexin 3 differentially regulate the tumorigenic properties of cutaneous squamous cell carcinoma
O'Donnell, B. L.; Johnston, D.; Bhatt, A.; Kardan, Z.; Stefan, D.; Bysice, A.; Sayedyahossein, S.; Dagnino, L.; Cecchini, M.; Loganathan, S. K.; Roth, K.; Penuela, S.
10.1101/2024.04.08.588550 — cancer biology — Posted on 2024-09-07
4465 Subtype-specific Patterns of Evolution and Clinically Relevant Genomic Instability in Wilms Tumour
Cresswell, G. D.; Chagtai, T.; Al-Saadi, R.; Treger, T. D.; Madhan, G.; Mifsud, B.; Vujanic, G.; Williams, R. D.; Luscombe, N. M.; Pritchard-Jones, K.; Mifsud, W.
10.1101/2024.09.04.610994 — cancer biology — Posted on 2024-09-07
4466 Claudin-4 remodeling of nucleus-cell cycle crosstalk maintains ovarian tumor genome stability and drives resistance to genomic instability-inducing agents.
Bitler, B. G.; Villagomez, F. R.; Lang, J.; Nunez-Avellaneda, D.; Behbakht, K.; Dimmick, H. L.; Webb, P.; Nephew, K. P.; Neville, M.; Woodruff, E. R.
10.1101/2024.09.04.611120 — cancer biology — Posted on 2024-09-07
4467 Interplay of ferroptotic and apoptotic cell death and its modulation by BH3-mimetics
Qiu, Y.; Hüther, J. A.; Wank, B.; Rath, A.; Tykwe, R.; Laschat, S.; Conrad, M.; Stöhr, D.; Rehm, M.
10.1101/2024.09.04.611207 — cancer biology — Posted on 2024-09-07
4470 Invasive cancer and spontaneous regression two weeks after papillomavirus infection
Bilger, A.; Ward-Shaw, E. T.; Lee, D. L.; King, R. E.; Newton, M. A.; Buehler, D.; Matkowskyj, K. A.; Sundberg, J. P.; Rong, H.; Lambert, P. F.
10.1101/2024.09.04.611275 — cancer biology — Posted on 2024-09-07
4471 CD4+Foxp3E2+ regulatory T cell frequency predicts breast cancer prognosis and recurrence
Fusco, C.; Di Rella, F.; Liotti, A.; Colamatteo, A.; Ferrara, A. L.; Gigantino, V.; Collina, F.; Esposito, E.; Donzelli, I.; Porcellini, A.; Feola, A.; Micillo, T.; Perna, F.; Garziano, F.; Maniscalco, G. T.; Varricchi, G.; Mottola, M.; Zuccarelli, B.; De Simone, B.; di Bonito, M.; Matarese, G.; Accurso, A.; Pontillo, M.; Russo, D.; Insabato, L.; Spaziano, A.; Cantone, I.; Pezone, A.; De Rosa, V.
10.1101/2024.09.04.611142 — immunology — Posted on 2024-09-07
4474 Sex-Specific Cytokine, Chemokine, and Growth Factor Signatures in T1D Patients and Progressors
Girdhar, K.; Mine, K.; DaCosta, J. M.; Atkinson, M. A.; Ludvigsson, J.; Altindis, E.
10.1101/2024.09.05.611513 — immunology — Posted on 2024-09-07
4475 Responses of grapevine cells to physiological doses of ethanol, among which induced resistance to heat stress
Diot, A.; Madignier, G.; Di Valentin, O.; Djari, A.; Maza, E.; Chen, Y.; Blanchet, S.; Chervin, C.
10.1101/2024.08.31.610606 — plant biology — Posted on 2024-09-07
4480 Lipid-siRNA conjugate accesses a perivascular transport mechanism and achieves widespread and durable knockdown in the central nervous system
Sorets, A.; Schwensen, K.; Francini, N.; Kjar, A.; Abdulrahman, A.; Shostak, A.; Katdare, K.; Schoch, K.; Cowell, R.; Park, J.; Ligocki, A.; Ford, W.; Ventura-Antunes, L.; Hoogenboezem, E.; Prusky, A.; Castleberry, M.; Michell, D. L.; Miller, T.; Vickers, K.; Schrag, M.; Duvall, C.; Lippmann, E.
10.1101/2024.06.09.598079 — bioengineering — Posted on 2024-09-07
4481 Aged mice exhibit faster acquisition of intravenous opioid self-administration with variable effects on intake
Sharpe, A. L.; Liter, L. R.; Donohue, D.; Carter, K. A.; Vangeneugden, P.; Weaver, S.; Stout, M.; Beckstead, M. J.
10.1101/2024.09.03.611052 — animal behavior and cognition — Posted on 2024-09-07
4483 Effect of Genotype and Age on a Defined Microbiota in Gnotobiotic SCID Piglets
Widmer, K. M.; Rahic-Seggerman, F.; Forster, A.; Ahrens-Kress, A.; Sauer, M.; Mooyottu, S.; Vinithakumari, A.; Dunkerson-Kurzhumov, A.; Sponseller, B.; Kiupel, M.; Schmitz-Esser, S.; Tuggle, C. K.
10.1101/2024.09.03.611011 — genetics — Posted on 2024-09-07
4484 Variation in albumin glycation rates in birds suggests resistance to relative hyperglycaemia rather than conformity to the pace of life syndrome hypothesis
Moreno Borrallo, A.; Jaramillo Ortiz, S.; Schaeffer-Reiss, C.; Quintard, B.; Rey, B.; Bize, P.; Viblanc, V. A.; Boulinier, T.; Chastel, O.; S. Gutierrez, J.; Masero, J. A.; Bertile, F.; Criscuolo, F.
10.1101/2024.07.02.600014 — evolutionary biology — Posted on 2024-09-07
4485 Jaccard dissimilarity in stochastic community models based on the species-independence assumption
Iritani, R.; Ontiveros, V. L. J.; Alonso, D.; Capitan, J. A.; Godsoe, W.; Tatsumi, S.
10.1101/2022.12.13.520233 — ecology — Posted on 2024-09-07
4486 Data Release: High-Resolution Imaging and Segmentation of P7 Mouse Tissue Microarchitecture Using FIB-SEM and Machine Learning
Ackerman, D.; Avetissian, E.; Bleck, C. K. E.; Bogovic, J. A.; Innerberger, M.; Korff, W.; Li, W.-P.; Lu, Z.; Petruncio, A.; Preibisch, S.; Qiu, W.; Rhoades, J.; Saalfeld, S.; Silva, M.; Trautman, E. T.; Vorimo, R.; Weigel, A. V.; Yu, Z.; Zubov, Y.; CellMap Project Team,
10.1101/2024.09.05.611438 — cell biology — Posted on 2024-09-07
4487 Widespread occurrence of benzimidazole resistance SNPs in the canine hookworm, Ancylostoma caninum, in Australia
Abdullah, S.; Stocker, T.; Kang, H.; Scott, I.; Hayward, D.; Jaensch, S.; Ward, M.; Jones, M. K.; Kotze, A.; Slapeta, J.
10.1101/2024.09.05.611542 — microbiology — Posted on 2024-09-07
4488 Paramyxovirus matrix proteins modulate host cell translation via exon-junction complex interactions in the cytoplasm
Hung, C.-T.; Haas, G. D.; Watkinson, R. E.; Chiu, H.-P.; Kowdle, S.; Stevens, C. S.; Park, A.; Wohlschlegel, J.; Thibault, P. A.; Lee, B.
10.1101/2024.09.05.611502 — microbiology — Posted on 2024-09-07
4489 Efficient multiplex non-viral engineering and expansion of polyclonal γδ CAR-T cells for immunotherapy
Bridge, J.; Johnson, M. J.; Kim, J.; Wenthe, S.; Krueger, J.; Wick, B.; Kluesner, M.; Crane, A. T.; Bell, J.; Skeate, J. G.; Moriarity, B. S.; Webber, B. R.
10.1101/2024.09.03.611042 — immunology — Posted on 2024-09-07
4492 The molecular infrastructure of glutamatergic synapses in the mammalian forebrain
Peukes, J.; Lovatt, M.; Leistner, C.; Boulanger, J.; Morado, D. R.; Fuller, M. J. G.; Kukulski, W.; Zhu, F.; Komiyama, N. H.; Briggs, J. A. G.; Grant, S. G. N.; Frank, R. A. W.
10.1101/2021.02.19.432002 — neuroscience — Posted on 2024-09-07
4494 Remote ischemic conditioning attenuates transneuronal degeneration and promotes stroke recovery via CD36-mediated efferocytosis.
Ju, H.; Kim, I.-d.; Pavlova, I.; Mu, S.; Park, K. W.; Minkler, J.; Madkoor, A.; Wang, W.; Wang, X.; Wu, Z.; Yang, J.; Febbraio, M.; Cave, J. W.; Cho, S.
10.1101/2024.09.03.611124 — neuroscience — Posted on 2024-09-07
4495 Knocking out the carboxyltransferase interactor 1 (CTI1) in Chlamydomonas boosted oil content by fivefold without affecting cell growth
Li, Z.; Kim, M.; da Silva Nascimento, J. R.; Legeret, B.; Jorge, G. L.; Bertrand, M.; Beisson, F.; Thelen, J. J.; Li-Beisson, Y.
10.1101/2024.09.03.611075 — plant biology — Posted on 2024-09-07
4496 Estimating soil mineral nitrogen from data-sparse field experiments using crop model-guided machine learning approach
Gupta, R.; Pothapragada, S. K.; Xu, W.; Goel, P. K.; Barrera, M.; Saldanha, M.; Harley, J.; Morgan, K. T.; Zare, A.; Zotarelli, L.
10.1101/2024.09.03.610387 — physiology — Posted on 2024-09-07
4497 Reversible Downregulation of HLA Class I in Adenoid Cystic Carcinoma
Li, A.; Gonda, B. L.; von Paternos, A.; Codd, E. M.; Mitchell, D. R.; Herrman, M. D.; Dzu, T. Q.; Kalyan, P.; Gao, C.; Zhang, E.; Mendel, J. J.; Thierauf, J. C.; Sadow, P. M.; Denize, T.; Yang, D.; Park, J. C.; Fintelmann, F. J.; Gao, X.; Merkin, R. D.; Bhan, A. K.; Faquin, W. C.; Wirth, L. J.; Wirth, D. L.; Kaluziak, S. T.; Iafrate, A. J.
10.1101/2024.09.03.610529 — cancer biology — Posted on 2024-09-07
4499 Mouse nephron formation is impaired by moderate-dose arsenical exposure
Alonso, C. A. I.; Haverfield, J.; Regalado, G.; Sellami, S.; Gagnon, N.; Rajaram, A.; Fiset, P. O.; Ryan, A. K.; Mann, K. K.; Gupta, I. R.
10.1101/2024.09.06.611740 — developmental biology — Posted on 2024-09-07
4500 Planar cell polarity coordination in a cnidarian embryo provides clues to animal body axis evolution
Uveira, J.; Donati, A.; Leria, M.; Lechable, M.; Lahaye, F.; Vesque, C.; Houliston, E.; Momose, T.
10.1101/2024.09.05.609312 — developmental biology — Posted on 2024-09-07
4501 The Drosophila myogenic inhibitor Him gene is essential for adult muscle function and muscle stem cell maintenance
Mitchell-Gee, R.; Hoff, R.; Vishal, K.; Hancock, D.; McKitrick, S.; Newnes-Querejeta, C.; Lovato, T.; Cripps, R.; Taylor, M.
10.1101/2024.09.06.611611 — developmental biology — Posted on 2024-09-07
4502 Calpains Orchestrate Secretion of Annexin-containing Microvesicles during Membrane Repair
Williams, J. K.; Ngo, J. M.; Murugupandiyan, A.; Croall, D. E.; Hartzell, H. C.; Schekman, R.
10.1101/2024.09.05.611512 — cell biology — Posted on 2024-09-07
4503 Single-cell transcriptome analysis reveals CD34 as a novel marker of human sinoatrial node pacemaker cardiomyocytes
Lim, A. A.; Pouyabahar, D.; Ashraf, M.; Huang, K.; Lohbihler, M.; Chang, M. L.; Murareanu, B. M.; Tran, T.; Mazine, A.; Bader, G.; Laksman, Z.; Protze, S. I.
10.1101/2024.09.06.611657 — cell biology — Posted on 2024-09-07
4506 Control of alveolar bone development, homeostasis, and socket healing by salt inducible kinases
Tokavanich, N.; Chan, B.; Strauss, K.; Castro, C.; Arai, Y.; Nagata, M.; Foretz, M.; Brooks, D. J.; Ono, N.; Ono, W.; Wein, M.
10.1101/2024.09.04.611228 — developmental biology — Posted on 2024-09-07
4508 Wnt/β-catenin signalling underpins juvenile Fasciola hepatica growth and development
Armstrong, R.; Marks, N. J.; Geary, T. G.; Harrington, J.; Selzer, P.; Maule, A. G.
10.1101/2024.09.04.611166 — developmental biology — Posted on 2024-09-07
4509 Ciliary marginal zone of the developing human retina maintains retinal progenitor cells until late gestational stages
Eldred, K. C.; Edgerton, S. J.; Ortuno-Lizaran, I.; Wohlschlegel, J.; Sherman, S. M.; Petter, S.; Wyatt-Draher, G.; Hoffer, D.; Glass, I.; La Torre, A. C.; Reh, T. A.
10.1101/2024.09.03.611053 — developmental biology — Posted on 2024-09-07
4512 Nodal Modulator (NOMO) is a force-bearing transmembrane protein required for muscle differentiation
Naughton, B.; Devarkar, S. C.; Mallik, S.; Oxendine, S.; Junnarkar, S.; Ren, Y.; Todorow, V.; Berro, J.; Kirstein, J.; Xiong, Y.; Schlieker, C.
10.1101/2024.09.06.611727 — cell biology — Posted on 2024-09-07
4514 PI3K/AKT Signaling Mediates Stress-Inducible Amyloid Aggregation Through c-myc
Lacroix, E.; Momchilova, E. A.; Chandhok, S.; Padavu, M.; Zapf, R.; Audas, T. E.
10.1101/2024.09.05.611538 — cell biology — Posted on 2024-09-07
4517 PIEZO-dependent mechano-sensing of the niche is essential for intestinal stem cell fate decision and maintenance
Baghdadi, M. B.; Rao-Bhatia, A.; Houtekamer, R. M.; Whelen, M.; Ayyaz, A.; Perez-Gonzalez, C.; Gropplero, G.; Loe, A. K.; Chen, X.; Huang, X.; Descroix, S.; Wrana, J. L.; Gloerich, M.; Vignjevic, D.; Kim, T.-H.; Perrin, L.; Diz-Munoz, A.; Decker, L.; Bouras, R.; Bergert, M.; Afkhami-Poostchi, A.
10.1101/2024.09.06.611641 — cell biology — Posted on 2024-09-07
4519 Acetylation of lysine 82 initiates TDP-43 nuclear loss of function by disrupting its nuclear import
Zhang, S.; Vazquez-Sanchez, S.; Lu, S.; Baughn, M. W.; Lim, J.; Oung, S.; Gao, L.; Diedrich, J. K.; Yates, J. R.; Yu, H.; Ravits, J.; Cleveland, D. W.
10.1101/2024.09.04.611121 — neuroscience — Posted on 2024-09-07
4522 ABBA, a novel tool for whole-brain mapping, reveals brain-wide differences in immediate early genes induction following learning
Chiaruttini, N.; castoldi, C.; Requie, L. M.; Camarena-Delgado, C.; Dal Bianco, B.; Graeff, J.; Seitz, A.; Silva, B. A.
10.1101/2024.09.06.611625 — neuroscience — Posted on 2024-09-06
4524 Like sisters but not twins - vasopressin and oxytocin excite BNST neurons via cell type-specific expression of oxytocin receptor to reduce anxious arousal
Francesconi, W.; Olivera-Pasilio, V.; Berton, F.; Olson, S. L.; Chudoba, R.; Monroy, L. M.; Krabichler, Q.; Grinevich, V.; Dabrowska, J.
10.1101/2024.09.06.611656 — neuroscience — Posted on 2024-09-06
4525 A hippocampal astrocytic sequence emerges during learning and memory
Senne, R. A.; Suthard, R. L.; Cao, R.; Monasterio, A.; Ruesch, E. A.; Buzharsky, M. D.; Howard, M.; Ramirez, S.
10.1101/2024.09.06.611660 — neuroscience — Posted on 2024-09-06
4526 Electrophysiological responses reveal a dedicated learning mechanism to process salient consonant sounds in human newborns
Barbieri, P.; Sarasso, P.; Rossi Sebastiano, A.; Frascaroli, J.; Poles, K.; Peila, C.; Coscia, A.; Garbarini, F.; Ronga, I.
10.1101/2024.09.06.611655 — neuroscience — Posted on 2024-09-06
4527 T cell correction pipeline for Inborn Errors of Immunity
Mamia, K.; Kolbeinsdottir, S.; Li, Z.; Labun, K.; Komisarczuk, A.; Keskitalo, S.; Reint, G.; Haugen, F. H.; Lindestad, B. O.; Gjerdingen, T. J.; Tuhkala, A.; Ervik, C. W.; Kopcil, P.; Fatkhutdinov, N.; Szymanska, M.; Tolo, E.; Glumoff, V.; Saarela, J.; Michelsen, T. M.; Schalin-Jantti, C.; Olweus, J.; Leinonen, E.; Varjosalo, M.; Valen, E.; Hautala, T.; Enge, M.; Martelius, T.; Dahal-Koirala, S.; Haapaniemi, E.
10.1101/2024.09.03.610811 — bioengineering — Posted on 2024-09-06
4528 Enhanced Ultrasound Image Formation with Computationally Efficient Cross-Angular Delay Multiply and Sum Beamforming
Smith, C. A. B.; Toulemonde, M.; Lerendegui, M.; Riemer, K.; Malounda, D.; Weinberg, P. D.; Shapiro, M. G.; Tang, M.-X.
10.1101/2024.09.03.611015 — bioengineering — Posted on 2024-09-06
4530 A universal limit for mammalian lifespan revealed by epigenetic entropy
Alba-Linares, J. J.; Tejedor, J. R.; Fernandez, A. F.; Perez, R. F.; Fraga, M. F.
10.1101/2024.09.06.611669 — molecular biology — Posted on 2024-09-06
4535 Outbreak of Western equine encephalitis virus infection associated with neurological disease in horses following a nearly 40-year intermission period in Argentina
Vissani, M. A.; Alamos, F.; Tordoya, M. S.; Minatel, L.; Schammas, J. M.; Dus Santos, M. J.; Trono, K.; Barrandeguy, M. E.; Balasuriya, U.; Carossino, M.
10.1101/2024.09.06.611705 — microbiology — Posted on 2024-09-06
4537 Passage of Zika virus in Rag1-deficient mice selects for unique envelope glycosylation motif mutants that show enhanced replication
Suhrbier, A.; Nakayama, E.; Tang, B.; Stewart, R.; Cox, A. L.; Yan, K.; Bishop, C.; Dumenil, T.; Nguyen, W.; Slonchak, A.; Sng, J.; Khromykh, A. A.; Lutzky, V. P.; Rawle, D. J.
10.1101/2024.09.06.611742 — microbiology — Posted on 2024-09-06
4539 Exploring the Exclusive Isolation of Pseudomonas syringae in Peltigera Lichens via metabolite analysis and growth assays
Ramirez Carrera, N.; Vinchira-Villarraga, D.; Rabiey, M.; Sigurbjornsdottir, M. A.; Heidmarsson, S.; Vilhelmsson, O.; Jackson, R. W.
10.1101/2024.09.06.611675 — microbiology — Posted on 2024-09-06
4542 Nanoparticle-Supported, Rapid, and Electronic Detection of SARS-CoV-2 Antibodies and Antigens at Attomolar Level
Choi, Y.; Mirjalili, S.; Ikbal, M. A.; McClure, S.; Clemens, S.; Solano, J.; Heggland, J.; Zuo, J.; Wang, C.
10.1101/2024.09.04.611305 — microbiology — Posted on 2024-09-06
4543 Uukuniemi virus infection causes a pervasive remodelling of the RNA-binding proteome in tick cell cultures
Wilson, A.; Kamel, W.; Davies, K.; Bell-Sakyi, L.; Lamont, D.; Demyanenko, Y.; Kitano, E.; Noerenberg, M.; Kohl, A.; Mohammed, S.; Castello, A.; Brennan, B.
10.1101/2024.09.06.611624 — microbiology — Posted on 2024-09-06
4544 Post-transcriptional regulation by TIA1 and TIAL1 controls the transcriptional program enforcing T cell quiescence.
Osma-Garcia, I. C.; Maloudi, O.; Mouysset, M.; Capitan-Sobrino, D.; Nguyen, T.-M. M.; Aubert, Y.; Diaz-Munoz, M. D.
10.1101/2024.09.03.608755 — immunology — Posted on 2024-09-06
4545 The Multiple Roles of Gamma Interferon in Intraepithelial T Cell-Villous Enterocyte Interactions in Active Celiac Disease
Johnson, J. E.; Agrawal, K.; Al-Lamki, R. S.; Zhang, F.; Xi, W. D.; Liburd, S.; Zsuzsanna, Z.; Rodriguez, L.; Martins, A. J.; Sefik, E.; Flavell, R.; Robert, M. E.; Pober, J. S.
10.1101/2024.09.03.610908 — immunology — Posted on 2024-09-06
4546 Reward timescale controls the rate of behavioral and dopaminergic learning
Burke, D. A.; Taylor, A.; Jeong, H.; Lee, S. A.; Wu, B.; Floeder, J. R.; K Namboodiri, V. M.
10.1101/2023.03.31.535173 — neuroscience — Posted on 2024-09-06
4553 Addressing the dynamic nature of reference data: a new nt database for robust metagenomic classification
Marti, J. M.; Kok, C. R.; Thissen, J. B.; Mulakken, N. J.; Avila-Herrera, A.; Jaing, C. J.; Allen, J. E.; Be, N. A.
10.1101/2024.06.12.598617 — bioinformatics — Posted on 2024-09-06
4555 Next generation APOBEC3 inhibitors: Optimally designed for potency and nuclease stability
Hedger, A. K.; Myint, W.; Lee, J. M.; Suchenski-Loustaunau, D.; Balachandran, V.; Shaqra, A. M.; Kurt Yilmaz, N.; Watts, J.; Matsuo, H.; Schiffer, C. A.
10.1101/2024.09.05.611238 — biochemistry — Posted on 2024-09-06
4557 Molecular insights into the stimulation of SNM1A nuclease activity by CSB during interstrand crosslink processing
Roddan, R.; Nathan, W. J.; Newman, J. A.; El-Sagheer, A. H.; Wilson, D. M.; Brown, T.; Schofield, C. J.; McHugh, P. J.
10.1101/2024.09.05.611390 — biochemistry — Posted on 2024-09-06
4558 USP24 is an ISG15 cross-reactive deubiquitinasethat mediates IFN-I production by de-ISGylatingthe RNA helicase MOV10
Mukhopadhyay, R.; Draganov, S. D.; Akkermans, J. J. L. L.; Kikkert, M.; Knobeloch, K.-P.; Fritz, G.; Guzman, M.; Zuniga, S.; Kim, R. Q.; Kessler, B. M.; Pinto-Fernandez, A.; Geurink, P. P.; Sapmaz, A.
10.1101/2024.09.06.611391 — biochemistry — Posted on 2024-09-06
4559 The isoniazid analog IQG-607 is not a direct substrate for the Mycobacterium tuberculosis catalase-peroxidase KatG
Barse, L. Q.; Roth, C. D.; Dadda, A. d. S.; Rambo, R. S.; Dalberto, P. F.; Pissinate, K.; Nunes, J. E. S.; Etchart, R. J.; Machado, P.; Basso, L. A.; Bizarro, C. V.
10.1101/2024.09.05.611129 — biochemistry — Posted on 2024-09-06
4560 Interchromosomal segmental duplication drives translocation and loss of P. falciparum histidine-rich protein 3
Hathaway, N. J.; Kim, I. E.; Young, N. W.; Hui, S. T.; Crudale, R.; Giesbrecht, D.; Liang, E. Y.; Nixon, C. P.; Juliano, J. J.; Parr, J. B.; Bailey, J. A.
10.1101/2022.12.07.519189 — genomics — Posted on 2024-09-06
4562 ER stress relief drives beta cell proliferation
Bourgeois, S.; Van Mulders, A.; Heremans, Y.; Leuckx, G.; Willems, L.; Coenen, S.; Degroote, L.; Pierreux, J.; Kancheva, D.; Scheyltjens, I.; Movahedi, K.; Carlotti, F.; de Koning, E.; Yi, X.; Vinci, C.; Tong, Y.; Cnop, M.; Heimberg, H.; De Leu, N.; Staels, W.
10.1101/2024.09.06.611615 — molecular biology — Posted on 2024-09-06
4563 GelGenie: an AI-powered framework for gel electrophoresis image analysis
Aquilina, M.; Wu, N. J. W.; Kwan, K.; Busic, F.; Dodd, J.; Nicolas-Saenz, L.; O'Callaghan, A.; Bankhead, P.; Dunn, K. E.
10.1101/2024.09.06.611479 — molecular biology — Posted on 2024-09-06
4565 Chlamydia muridarum Causes Persistent Subclinical Infection and Elicits Innate and Adaptive Immune Responses in C57BL/6J, BALB/cJ and J:ARC(S) Mice Following Exposure to Shedding Mice
Mishkin, N.; Carrasco, S. E.; Palillo, M. B.; Momtsios, P.; Woods, C.; Henderson, K. S.; Longhini, A. L. F.; Otis, C.; Gardner, R.; Joseph, A. M.; Sonnenberg, G. F.; Palillo, J.; Ricart Arbona, R. J.; Lipman, N. S.
10.1101/2024.07.16.603732 — microbiology — Posted on 2024-09-06
4570 Identification of new genes on a whole genome scale using saturated reporter transposon mutagenesis
Goodall, E. C. A.; Hodges, F.; Kok, W.; Permana, B.; Cuddihy, T.; Yang, Z.; Kahler, N.; Shires, K.; Pullela, K.; Torres, V. V. L.; Rooke, J.; Delhaye, A.; Bryant, J. A.; Forde, B. M.; Hemm, M.; henderson, i.
10.1101/2024.09.06.611592 — microbiology — Posted on 2024-09-06
4572 Macrophage-intrinsic MDA5-IRF5 axis drives HIV-1 icRNA-induced inflammatory responses
Gummuluru, S.; Ramaswamy, S.; Akiyama, H.; Berrigan, J.; Quinones, A.; Olson, A.; Chen, Y.; Lang, Y. M.; Henderson, A. J.; Asundi, A.; Sagar, M.
10.1101/2024.09.06.611547 — microbiology — Posted on 2024-09-06
4573 Dendritic cell effector mechanisms and tumor immune microenvironment infiltration define TLR8 modulation and PD-1 blockade
Torres, D. A. R.; Wise, J.; Zhao, B.; Oliveira-Costa, J. P.; Cavallaro, S.; Sadow, P.; Fang, J.; Yilmaz, O.; Patel, A.; Loosbroock, C.; Sade-Feldman, M.; Faden, D. L.; Stott, S. L.
10.1101/2024.09.03.610636 — immunology — Posted on 2024-09-06
4574 Nasopharyngeal specific selection and emergence of SARS-CoV-2 spike fusion peptide mutation P812S during chronic infection
Cheng, M. T. K.; Altaf, M.; Martin, D. P.; Ruis, C.; Sievers, B. L.; Kamelian, K.; Morse, R. B.; Abdullahi, A.; Meng, B.; Csiba, K.; Cambridge NIHR Bioresource, ; Kemp, S. A.; Gupta, R. K.
10.1101/2024.09.05.611549 — immunology — Posted on 2024-09-06
4575 Simulating freely-diffusing single-molecule FRET data with consideration of protein conformational dynamics
Losey, J.; Jauch, M.; Cortes-Cubero, A.; Wu, H.; Polasa, A.; Sauve, S.; Rivera, R.; Matteson, D. S.; Moradi, M.
10.1101/2021.01.19.427359 — biophysics — Posted on 2024-09-06
4579 Targeting Fibroblast-Endothelial Interactions in LAM Pathogenesis: 3D Spheroid and Spatial Transcriptomic Insights for Therapeutic Innovation
Koc-Gunel, S.; Liu, E. C.; Gautam, L. K.; Calvert, B. A.; Murthy, S.; Harriott, N. C.; Nawroth, J. C.; Zhou, B.; Krymskaya, V. P.; Ryan, A. L.
10.1101/2023.06.12.544372 — cell biology — Posted on 2024-09-06
4583 CXCR3-expressing myeloid cells recruited to the hypothalamus protect against diet-induced body mass gain and metabolic dysfunction
Mendes, N.; Zanesco, A.; Aguiar, C.; Rodrigues-Luiz, G. F.; Silva, D.; Campos, J.; Camara, N. O. S.; Moraes-Vieira, P.; Araujo, E.; Velloso, L. A.
10.1101/2024.01.16.575893 — neuroscience — Posted on 2024-09-06
4584 An enhancer-AAV toolbox to target and manipulate distinct interneuron subtypes
Furlanis, E.; Dai, M.; Leyva Garcia, B.; Vergara, J.; Pereira, A.; Pelkey, K.; Tran, T.; Gorissen, B. L.; Vlacho, A.; Hairston, A.; Huang, S.; Dwivedi, D.; Du, S.; Wills, S.; McMahon, J.; Lee, A. T.; Chang, E. F.; Razzaq, T.; Qazi, A.; Vargish, G.; Yuan, X.; Caccavano, A.; Hunt, S.; Chittajallu, R.; McLean, N.; Hewit, L.; Paranzino, E.; Rice, H.; Cummins, A. C.; Plotnikova, A.; Mohanty, A.; Tangen, A. C.; Shin, J. H.; Azadi, R.; Eldridge, M. A. G.; Alvarez, V. A.; Averbeck, B. B.; Alyahyay, M.; Reyes Vallejo, T.; Soheib, M.; Vattino, L. G.; MacGregor, C. P.; Banks, E.; Olah, V. J.; Naskar, S.;
10.1101/2024.07.17.603924 — neuroscience — Posted on 2024-09-06
4585 Ethanol reduces grapevine water consumption by limiting transpiration
Ait Kaci, N.; Diot, A.; Quinquiry, B.; Yobregat, O.; Pellegrino, A.; Maury, P.; Chervin, C.
10.1101/2024.08.31.610611 — plant biology — Posted on 2024-09-06
4591 Is water vole diet consistent with the plant hypothesis for explaining population fluctuations?
Lisse, H.; Buronfosse, M.; Jacquet, C.; Sobczyk-Moran, G.; Ramadier, E.; Fafournoux, A.; Lattard, V.; Pinot, A.
10.1101/2024.09.04.611276 — ecology — Posted on 2024-09-06
4592 A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models
Puray-Chavez, M.; Eschbach, J. E.; Xia, M.; LaPak, K.; Zhou, Q.; Jasuja, R.; Pan, J.; Xu, J.; Zhou, Z.; Mohammed, S.; Wang, Q.; Lawson, D.; Djokic, S.; Hou, G.; Ding, S.; Brody, S. L.; Major, M. B.; Goldfarb, D.; Kutluay, S. B.
10.1101/2024.01.07.574522 — microbiology — Posted on 2024-09-06
4593 A next-generation, histological atlas of the human brain and its application to automated brain MRI segmentation
Casamitjana, A.; Mancini, M.; Robinson, E.; Peter, L.; Annunziata, R.; Althonayan, J.; Crampsie, S.; Blackburn, E.; Billot, B.; Atzeni, A.; Puonti, O.; Balbastre, Y.; Schmidt, P.; Hughes, J.; Augustinack, J.; Edlow, B. L.; Zollei, L.; Thomas, D.; Kliemann, D.; Bocchetta, M.; Strand, C.; Holton, J.; Jaunmuktane, Z.; Iglesias, J. E.
10.1101/2024.02.05.579016 — neuroscience — Posted on 2024-09-06
4595 HOXB6 and HOXB8 control immune-cancer cell interactions in pancreatic cancer.
Bertonnier-Brouty, L.; Achanta, K.; Andersson, J.; Bsharat, S.; Singh, T.; Kaprio, T.; Hagstrom, J.; Haglund, C.; Seppanen, H.; Prasad, R. B.; Artner, I.
10.1101/2024.09.06.611619 — cancer biology — Posted on 2024-09-06
4598 IL-6 and IL-27 negatively regulate CRTAM-expressing CD4+ T-cells associated with lymphoid-driven synovitis.
Derrac Soria, A.; Lewis, M. J.; Liu, X.; Twohig, J. P.; Monaco, F.; Dimonte, S.; Cardus Figueras, A.; Morrin, A.; Guy, C.; Cossins, B. C.; Benson, R.; Andrews, R.; Choy, E. H.; Garside, P.; Siebzehnrubl, F. A.; Rodrigues, N.; Jenkins, B. J.; Pitzalis, C.; Jones, G. W.; Jones, S. A.
10.1101/2024.09.03.610972 — immunology — Posted on 2024-09-06
4599 Brain Morphometry and Chronic Inflammation in Bangladeshi Children Growing up in Extreme Poverty
Turesky, T. K.; Pirazzoli, L.; Shama, T.; Kakon, S. H.; Haque, R.; Islam, N.; Someshwar, A.; Gagoski, B.; Petri, W.; Nelson, C. A.; Gaab, N.
10.1101/2021.12.26.474220 — neuroscience — Posted on 2024-09-06
4600 Diurnal regulation of Acyl-CoA synthetase 3 (ACSF3) underlies daily mitochondrial lysine-malonylation and hepatic metabolism
LeQuestel, E.; Besnard, C.; Atger, F.; Foucher, Y.; Tollec, A.; Pakulska, V.; Rodrigues Oliveira, A.; Clotteau, C.; Gourdel, M.; Nemazanyy, I.; Croyal, M.; Coute, Y.; Jacobi, D.; Cariou, B.; Mauvoisin, D.
10.1101/2024.09.03.607283 — physiology — Posted on 2024-09-06
4602 Enhancing efficacy of the MEK inhibitor trametinib with paclitaxel in KRAS-mutated colorectal cancer
Ghosh, S.; Fan, F.; Powell, R. T.; Park, Y.; Stephan, C. C.; Kopetz, S.; Ellis, L.; Bhattacharya, R.
10.1101/2024.09.05.611458 — cancer biology — Posted on 2024-09-06
4605 Characterization of tumor heterogeneity through segmentation-free representation learning
Tan, J.; Le, H.; Deng, J.; Liu, Y.; Hao, Y.; Hollenberg, M.; Liu, W.; Wang, J. M.; Xia, B.; Ramaswami, S.; Mezzano, V.; Loomis, C.; Murrell, N.; Moreira, A. L.; Cho, K.; Pass, H. I.; Wong, K.-K.; Ban, Y.; Neel, B. G.; Tsirigos, A.; Fenyo, D.
10.1101/2024.09.05.611431 — cancer biology — Posted on 2024-09-06
4612 Serine chirality guides metabolic flow between one-carbon metabolism and neuromodulator synthesis
Suzuki, M.; Adachi, K.; Wiriyasermukul, P.; Fukumura, M.; Tamura, R.; Hirano, Y.; Aizawa, Y.; Miyamoto, T.; Taniguchi, S.; Toda, M.; Homma, H.; Kanekura, K.; Yasuoka, K.; Kanai, T.; Sugimoto, M.; Nagamori, S.; Yasui, M.; Sasabe, J.
10.1101/2024.09.03.610855 — developmental biology — Posted on 2024-09-06
4613 Enhancing HLA-DR in Cytotoxic T Lymphocytes is crucial for the development of efficient adoptive T cell Therapies for Breast Cancer
Salvador, R.; Correia, B. F.; Grosa, D.; Martins, T.; Baal, S. C. S.; Saraiva, D. P.; Cristovao-Ferreira, S.; Pereira, I. L.; de Almeida, C. R.; Fior, R.; Jacinto, A.; Mathias, C.; Braga, S.; Cabral, M. d. g.
10.1101/2024.09.03.610810 — immunology — Posted on 2024-09-06
4618 The small MAF transcription factor MAFG co-opts MITF to promote melanoma progression
Vera, O.; Martinez, M.; Soto-Vargas, Z.; Wang, K.; Xu, X.; Ruiz-Buceta, S.; Mecozzi, N.; Chadourne, M.; Posorske, B.; Angarita, A.; Bok, I.; Liu, Q.; Murikipudi, H.; Kim, Y.; Messina, J. L.; Tsai, K. Y.; Major, M.; Lau, E. K.; Yu, X.; Ibanez-de-Caceres, I.; Karreth, F. A.
10.1101/2024.09.03.611024 — cancer biology — Posted on 2024-09-06
4621 Synchrotron Tomography-Based Finite Element Analysis of Vertebral Endplate Loading Reveals Functional Roles for Architectural Features
Chen, J.; Parmenter, A. L.; Sharma, A.; Newham, E.; Bele, E.; Marussi, S.; Pitsillides, A. A.; Terrill, N. J.; Gupta, H. S.; Lee, P. D.
10.1101/2024.09.03.610954 — bioengineering — Posted on 2024-09-06
4623 Origin and evolutionary trajectories of brown algal sex chromosomes
Barrera-Redondo, J.; Lipinska, A. P.; Liu, P.; Dinatale, E.; Cossard, G.; Bogaert, K.; Hoshino, M.; Craig, R.; Avia, K.; Avdievich, E.; Leiria, G.; Liesner, D.; Luthringer, R.; Godfroy, O.; Heesch, S.; Nehr, Z.; Peters, A. F.; Hoarau, G.; Pearson, G. A.; Aury, J.-M.; Wincker, P.; Denoeud, F.; Cock, J. M.; Haas, F. B.; Coelho, S. M.
10.1101/2024.01.15.575685 — evolutionary biology — Posted on 2024-09-06
4624 Disrupted developmental signaling induces novel transcriptional states
Patel, A.; Gonzalez, V.; Menon, T.; Shvartsman, S. Y.; Burdine, R. D.; Avdeeva, M.
10.1101/2024.09.05.610903 — developmental biology — Posted on 2024-09-06
4625 Multi-species genome-wide CRISPR screens identify conserved suppressors of cold-induced cell death
Lam, B.; Kajderowicz, K. M.; Keys, H. R.; Roessler, J. M.; Frenkel, E. M.; Kirkland, A.; Bisht, P.; El-Brolosy, M. A.; Jaenisch, R.; Bell, G. W.; Weissman, J. S.; Griffith, E. C.; Hrvatin, S.
10.1101/2024.07.25.605098 — cell biology — Posted on 2024-09-06
4626 Multi-tissue proteomics identifies a link between satellite DNA organization and heritable transposon repression in Drosophila
Chavan, A.; Skrutl, L.; Uliana, F.; Pfister, M.; Braendle, F.; Tirian, L.; Baptista, D.; Handler, D.; Burke, D. F.; Sintsova, A.; Beltrao, P.; Brennecke, J.; Jagannathan, M.
10.1101/2023.07.11.548599 — cell biology — Posted on 2024-09-06
4627 Prkra dimer senses double-stranded RNAs to dictate global translation efficiency
Lu, T.; Ma, P.; Chen, A.; Fang, H.; Xu, J.; Wang, M.; Su, L.; Wang, S.; Zhang, Y.; Wang, J.; Yang, B.; Shi, D.-L.; Zhou, Y.; Gong, Q.; Liu, X.; Mao, B.; Shao, M.
10.1101/2024.07.16.603655 — molecular biology — Posted on 2024-09-06
4629 Interhemispheric CA1 projections support spatial cognition and are affected in a mouse model of the 22q11.2 deletion syndrome
De Leon Reyes, N. S.; Bortolozzo-Gleich, M. H.; Nomura, Y.; Garcia Frigola, C.; Nieto, M.; Gogos, J.; Leroy, F.
10.1101/2024.09.05.611389 — neuroscience — Posted on 2024-09-06
4630 DNMT1-Mediated Regulation of Inhibitory Interneuron Migration Impacts Cortical Architecture and Function
Reichard, J.; Wolff, P.; Du, J.; Fullio, C. L.; Dorp, L.; Yildiz, C. B.; Linde, J.; Vollmer, J.; Kempf, S.; Graff, S.; Nabbefeld, G.; Singh, M.; Kuo, C.-C.; Mohan, N. K.; Vogel, T.; Musall, S.; Zimmer-Bensch, G. M.
10.1101/2024.09.04.611268 — neuroscience — Posted on 2024-09-06
4631 Complementary cognitive roles for D2-MSNs and D1-MSNs during interval timing
Bruce, R.; Weber, M. A.; Bova, A.; Volkman, R.; Jacobs, C.; Sivakumar, K.; Kim, Y.; Curtu, R.; Narayanan, N.
10.1101/2023.07.25.550569 — neuroscience — Posted on 2024-09-06
4633 The Zymoseptoria tritici effector Zt-11 contributes to aggressiveness in wheat
Karki, S. J.; Pilo, P.; Lawless, C.; Mastrodimos, N.; Burke, J.; Tiley, A.; Feechan, A.; Feechan, A.
10.1101/2024.09.04.611169 — plant biology — Posted on 2024-09-06
4634 Identification of leptolin as a novel anti-obesity adipokine
Liu, J.; Wang, B.; Su, Z.; Han, X.; He, M.; Zhao, Y.; Hou, Y.; Li, D.; Zhang, W.; Qin, L.; Wang, K.; Li, Y.; Yan, Y.; Yu, S.; Huang, X.; Yuwen, T.; Zheng, R.
10.1101/2024.09.03.610963 — physiology — Posted on 2024-09-06
4636 Vascular HIF2 signaling prevents cardiomegaly, alveolar congestion and capillary remodeling during chronic hypoxia
Albendea-Gomez, T.; Mendoza-Tamajon, S.; Castro-Mecinas, R.; Escobar, B.; Rocha, S. F.; Urra-Balduz, S.; Nicolas-Avila, J. A.; Oliver, E.; Villalba-Orero, M.; Martin-Puig, S.
10.1101/2024.09.03.610947 — pathology — Posted on 2024-09-06
4637 VHL synthetic lethality screens uncover CBF-beta as a negative regulator of STING
Bertlin, J. A.; Pauzaite, T.; Liang, Q.; Wit, N.; Williamson, J. C.; Sia, J. J.; Matheson, N. J.; Ortmann, B. M.; Mitchell, T. J.; Speak, A. O.; Zhang, Q.; Nathan, J. A.
10.1101/2024.09.03.610968 — cancer biology — Posted on 2024-09-06
4639 The Transcription Factor TCF21 is necessary for adoption of cell fates by Foxd1+ stromal progenitors during kidney development.
Finer, G.; Khan, M. D.; Zhou, Y.; Gadhvi, G.; Yacu, G. S.; Park, J.-S.; Gomez, R. A.; Sequeira-Lopez, M. L.; Quaggin, S. E.; Winter, D. R.
10.1101/2024.08.14.607910 — developmental biology — Posted on 2024-09-06
4641 Motor learning is regulated by GDNF levels in postnatal cerebellar Purkinje cells
Nagaeva, E.; Turconi, G.; Matlik, K.; Segerstrale, M.; Olfat, S.; Iivanainen, V.; Taira, T.; Andressoo, J.-O.
10.1101/2024.09.06.611586 — neuroscience — Posted on 2024-09-06
4643 Evaluating Physiological Indicators in Detecting Deception using the Comparison Question Test (CQT)
Rashid, A. M. S.; Carmichael, B.; Su, C.; Shi, K.; Lim, K.; Kumar, P. S.; Wan, N. J.; Govil, E.; Yap, D.
10.1101/2024.09.01.609623 — bioengineering — Posted on 2024-09-06
4646 Hippocampal neuronal activity is aligned with action plans
Zutshi, I.; Apostolelli, A.; Yang, W.; Zheng, Z.; Dohi, T.; Balzani, E.; Williams, A.; Savin, C.; Buzsaki, G.
10.1101/2024.09.05.611533 — neuroscience — Posted on 2024-09-06
4647 Additions to the list of arthropods of Reunion Island
Nibouche, S.; Sadeyen, J.; Dervin, S.; Gauche, M.; Merion, S.; Minatchy, J.; Fontaine, R.; Reynaud, P.; Michel, B.
10.1101/2024.09.03.610934 — zoology — Posted on 2024-09-06
4648 Regulatory start-stop elements in 5' untranslated regions pervasively modulate translation
Rendleman, J.; Haizel, S.; Wu, S.; Ge, X.; Liu, J.; Zou, H.; Mohammad, M. P.; Pressler, M.; Maity, S.; Hronova, V.; Gao, Z.; Herrmannova, A.; Lei, A.; Allgoewer, K.; Sultanov, D.; Hinckley, W. E.; Szkop, K.; Topisirovic, I.; Larsson, O.; Hatzoglou, M.; Valasek, L. S.; Vogel, C.
10.1101/2021.07.26.453809 — systems biology — Posted on 2024-09-06
4652 Nanomotion technology for testing azithromycin susceptibility of Salmonella enterica
Hinnu, M.; Mets, T.; Kerkez, I.; Putrins, M.; Kaldalu, N.; Cathomen, G.; Pla Verge, M.; Cichocka, D.; Sturm, A.; Tenson, T.; ERADIAMR,
10.1101/2024.09.05.611511 — microbiology — Posted on 2024-09-06
4653 Cortical beta oscillations map to shared brain networks modulated by dopamine
Chikermane, M.; Weedmeester, L.; Rajamani, N.; Köhler, R. M.; Merk, T.; Vanhoecke, J.; Horn, A.; Neumann, W.-J.
10.1101/2024.02.16.580657 — neuroscience — Posted on 2024-09-06
4656 Leukocytes have a heparan sulfate glycocalyx that regulates recruitment during inflammation
Priestley, M. J.; Hains, A. K.; Mulholland, I. Z.; Spijkers-Shaw, S.; Zubkova, O. V.; Saunders, A. J.; Dyer, D. P.
10.1101/2024.05.21.595098 — immunology — Posted on 2024-09-06
4657 Genomic characterization of foodborne Salmonella enterica and Escherichia coli isolates from Saboba district and Bolgatanga Municipality Ghana
Sunmonu, G. T.; Adzitey, F.; Odih, E. E.; Tibile, B. A.; Ekli, R.; Aduah, M.; Oaikhena, A. O.; Akinlabi, O. C.; Abia, A. L. K.; Amoako, D. G.; Okeke, I. N.
10.1101/2024.09.05.611394 — microbiology — Posted on 2024-09-06
4659 METTL3 inhibition-activated cGAS/STING axis enhances immunotherapy and PARP inhibitor sensitivity of lung carcinoma
Zhou, J.; He, J.; Lu, Y.; Yi, C.; Chang, X.; Tao, L.; Zhong, K.; Zhang, H.; Li, J.; Chen, Z.; Wang, H.
10.1101/2024.09.03.610931 — cancer biology — Posted on 2024-09-06
4660 Self-driving development of perfusion processes for monoclonal antibody production
Mueller, C.; Vuillemin, T.; Gadiyar, C. J.; Souquet, J.; Bielser, J. M.; Fagnani, A.; Sokolov, M.; von Stosch, M.; Feidl, F.; Butte, A.; Cruz Bournazou, M. N.
10.1101/2024.09.03.610922 — bioengineering — Posted on 2024-09-06
4661 NIRSTORM: a Brainstorm extension dedicated to functional Near Infrared Spectroscopy (fNIRS) data analysis, advanced 3D reconstructions, and optimal probe design.
Delaire, E.; Vincent, T.; Cai, Z.; Machado, A.; hugueville, L.; Schwartz, D.; Tadel, F.; Cassani, R.; Bherer, L.; JM Lina, j.-m.; Pelegrini-Issac, M.; Grova, C.
10.1101/2024.09.05.611463 — bioengineering — Posted on 2024-09-06
4662 Polyelectrolyte mannan from diatoms reshapes sunlit ocean microbiome
Krull, J.; Crawford, C. J.; Sidhu, C.; Solanki, V.; Bligh, M.; Rössler, L.; Singh, R. K.; Huang, G.; Robb, C. S.; Teeling, H. J.; Seeberger, P. H.; Schweder, T.; Hehemann, J.-H.
10.1101/2024.07.03.601839 — ecology — Posted on 2024-09-06
4665 Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis dependent functional plasticity.
Cox, D. J.; Connolly, S. A.; Maoldomhnaigh, C. O.; Brugman, A. A.; Thomas, O. S.; Duffin, E.; Gogan, K. M.; O Gallchobhair, O.; Murphy, D. M.; O'Rourke, S. A.; O'Connell, F.; Nadarajan, P.; Phelan, J. J.; Gleeson, L. E.; Basdeo, S. A.; Keane, J.
10.1101/2024.03.20.585747 — immunology — Posted on 2024-09-06
4666 Limited microglial metabolic improvement with time-restricted feeding in diet-induced obesity
Jiao, H.; Jermei, J.; Liang, X.; Correa-da-Silva, F.; Dorscheidt, M.; Rumanova, V. S.; Poormoghadam, D.; Foppen, E.; Korpel, N.; Stenvers, D. J.; Arias, A. P.; Liu, T.; Zhi, Z.; Kalsbeek, A.; Yi, C.-X.
10.1101/2024.09.04.611250 — immunology — Posted on 2024-09-06
4667 Neuropathic pain and distinct CASPR2 autoantibody IgG subclasses drive neuronal hyperexcitability
Habib, M.; Wiessler, A.-L.; Greguletz, P.; Niesner, M.; Selcho, M.; Abrante, L.; Werner, C.; Sodmann, A.; Koch, M.; Abdelhossein, Z.; Pruess, H.; Dargvainiene, J.; Lewerenz, J.; Handreka, R.; Koertvelyessy, P.; Reinhold, D.; Thaler, F.; Pitarokoili, K.; Kittel, R.; Briese, M.; Sendtner, M.; Rittner, H.; Leypoldt, F.; Sommer, C.; Blum, R.; Doppler, K.; Villmann, C.
10.1101/2024.09.04.611282 — neuroscience — Posted on 2024-09-06
4669 Widespread Associations between Behavioral Metrics and Brain Microstructure in ASD
Ressa, H.; Newman, B. T.; Jacokes, Z.; McPartland, J.; Kleinhans, N. M.; Druzgal, T. J.; Pelphrey, K. A.; Van Horn, J. D.; the GENDAAR Research Consortium,
10.1101/2024.09.04.611183 — neuroscience — Posted on 2024-09-06
4672 Nicotinic Acetylcholine Receptors on Osteocytes Impact Bone Mechanoadaptation in a Sexually Dimorphic Manner
Mora-Antoinette, M.; Garcia-Ortiz, A.; Obaji, M.; Saffari, A. W.; Matthews, M. D.; Lewis, K. J.
10.1101/2023.10.01.556129 — physiology — Posted on 2024-09-06
4675 Collective gradient sensing by dilute swimming bacteria without clustering
Kai, T.; Abe, T.; Yoshinaga, N.; Nakamura, S.; Kudo, S.; Toyabe, S.
10.1101/2022.11.17.516991 — biophysics — Posted on 2024-09-06
4676 Blocking uncertain mispriming errors of PCR
Takahashi, T.; Aoyanagi, H.; Pigolotti, S.; Toyabe, S.
10.1101/2024.04.19.590219 — bioengineering — Posted on 2024-09-06
4680 Evolutionary adaptation under climate change: Aedes sp. demonstrates potential to adapt to warming
Couper, L. I.; Dodge, T. O.; Hemker, J. A.; Kim, B. Y.; Exposito-Alonso, M.; Brem, R. B.; Mordecai, E. A.; Bitter, M. C.
10.1101/2024.08.23.609454 — evolutionary biology — Posted on 2024-09-06
4681 Single-cell multiome uncovers differences in glycogen metabolism underlying species-specific speed of development
de la Porte, A.; Schröder, J.; Thomas, M.; Geuder, J.; Sterr, M.; Pastor, X.; Sanderson, L. E.; Barakat, T. S.; Enard, W.; Marr, C.; Schröter, C.; Drukker, M.
10.1101/2024.09.03.610938 — developmental biology — Posted on 2024-09-06
4682 Single cell transcriptional changes across the blood stages of artemisinin resistant K13C580Y mutant Plasmodium falciparum upon dihydroartemisinin exposure
Oduor, C. I.; Connelly, S. V.; Cunningham, C.; Rustamzade, N.; Zuromski, J.; Chin, D. M.; Nixon, C. P.; Kurtis, J. D.; Juliano, J. J.; Bailey, J. A.
10.1101/2023.12.06.570387 — microbiology — Posted on 2024-09-06
4683 Contributions of mirror-image hair cell orientation to mouse otolith organ and zebrafish neuromast function
Ono, K.; Jarysta, A.; Hughes, N. C.; Jukic, A.; Chang, H. H. V.; Deans, M. R.; Eatock, R. A.; Cullen, K. E.; Kindt, K. S.; Tarchini, B.
10.1101/2024.03.26.586740 — neuroscience — Posted on 2024-09-06
4684 Unique Signatures of Highly Constrained Genes Across Publicly Available Genomic Databases
Agrawal, P.; Schmitz-Abe, K. E.; Li, Q.; Greene, S.; Borrelli, M.; Luo, S.; Ramesh, M.
10.1101/2024.09.05.611529 — genetics — Posted on 2024-09-05
4685 Changing dynamics of Aedes aegypti invasion and vector-borne disease risk for rural communities in the Peruvian Amazon
Fikrig, K. M.; Noriega, A. O.; Rodriguez, R. A.; Bardales, J.; Rivas, J.; Reyna, B.; Izquierdo, G.; Morrison, A. C.; Harrington, L. C.
10.1101/2024.09.04.611168 — ecology — Posted on 2024-09-05
4687 Is water vole diet consistent with the plant hypothesis for explaining population fluctuations?
Pinot, A.; Lisse, H.; Lattard, V.; Fafournoux, A.; Buronfosse, M.; Ramadier, E.; Jacquet, C.; Sobczyk-Moran, G.
10.1101/2024.09.04.611276 — ecology — Posted on 2024-09-05
4688 Deciphering the nanoscale architecture of presynaptic actin using a micropatterned presynapse-on-glass model
Tumminia, S.; Mezache, L.; Wiesner, T.; Vianay, B.; Thery, M.; Papandreou, M.-J.; Leterrier, C.
10.1101/2024.09.05.611287 — neuroscience — Posted on 2024-09-05
4690 Dissociable dynamic effects of expectation during statistical learning.
McDermott, H. H.; De Martino, F.; Schwiedrzik, C. M.; Auksztulewicz, R.
10.1101/2024.09.05.611380 — neuroscience — Posted on 2024-09-05
4691 Hippocampal neuronal activity is aligned with action plans
Zutshi, I.; Apostolelli, A.; Yang, W.; Zheng, Z.; Dohi, T.; Balzani, E.; Williams, A.; Savin, C.; Buzsaki, G.
10.1101/2024.09.05.611533 — neuroscience — Posted on 2024-09-05
4695 Honey bee egg composition changes seasonally and after acute maternal virus infection
Chapman, A.; McAfee, A. A.; Wrightson, K. L. C.; Magana, A. A.; Tarpy, D. R.; Fine, J. D.; Rempel, Z.; Peters, K.; Currie, R. W.; Hoover, S. E.; Foster, L. J.
10.1101/2024.09.05.611496 — zoology — Posted on 2024-09-05
4697 Conservation of mutation and recombination parameters between mammals and zebra finch
Prentout, D.; Bykova, D.; Hoge, C. R.; Hooper, D. M.; McDiarmid, C. S.; Wu, F.; Griffith, S.; de Manuel, M.; Przeworski, M.
10.1101/2024.09.05.611523 — evolutionary biology — Posted on 2024-09-05
4700 ADAR1 orchestrates the ZBP1-mediated PANoptosis and heart transplant rejection
Lu, H.; Jiang, J.; Huang, X.; Haig, A.; Gunaratnam, L.; Jevnikar, A.; Zhang, Z.-X.
10.1101/2024.09.05.611429 — molecular biology — Posted on 2024-09-05
4705 Transcriptome-scale analysis uncovers conserved residues in the hydrophobic core of the bacterial RNA chaperone Hfq required for small regulatory RNA stability
McQuail, J.; Krepl, M.; Katsuya-Gaviria, K.; Tabib-Salazar, A.; Burchell, L.; Bischler, T.; Gräfenhan, T.; Brear, P.; Sponer, J.; Luisi, B.; Wigneshweraraj, R.
10.1101/2024.09.05.607192 — microbiology — Posted on 2024-09-05
4706 Off-purpose activity of industrial and agricultural chemicals against human gut bacteria
Lindell, A. E.; Kamrad, S.; Roux, I.; Krishna, S.; Griesshammer, A.; Smith, T.; Guan, R.; Rad, D.; Faria, L.; Blasche, S.; Kleinstreuer, N. C.; Maier, L.; Patil, K. R.
10.1101/2024.09.05.610817 — microbiology — Posted on 2024-09-05
4707 SARS-CoV-2 Nsp15 antagonizes the cGAS-STING-mediated antiviral innate immune responses
Lee, B.; Chiu, H.-P.; Yeo, Y. Y.; Lai, T. Y.; Hung, C.-T.; Kowdle, S. S.; Haas, G. D.; Jiang, S.; Sun, W.
10.1101/2024.09.05.611469 — microbiology — Posted on 2024-09-05
4708 Endogenous retroviruses activate MARCO-mediated inflammatory response to block retroviral infection
Xuming, H.; Guo, W.; Wu, H.; Liu, J.; Chen, X.; Han, X.; Zhang, Y.; Zhang, Y.; Cao, Z.; Bao, Q.; Chai, W.; Chen, S.; Zhao, W.; Chen, G.; Cui, H.; Qi, X.
10.1101/2024.09.03.610969 — immunology — Posted on 2024-09-05
4710 Computational identification of small molecules for increased gene expression by synthetic circuits in mammalian cells
Pisani, M.; Calandra, F.; Rinaldi, A.; Cella, F.; Tedeschi, F.; Boffa, I.; Brunetti-Pierri, N.; Carissimo, A.; Napolitano, F.; Siciliano, V.
10.1101/2024.09.05.611507 — synthetic biology — Posted on 2024-09-05
4711 AI-Based Discovery and CryoEM Structural Elucidation of a KATP Channel Pharmacochaperone
Elsheikh, A.; Driggers, C. M.; Truong, H. H.; Yang, Z.; Allen, J.; Henriksen, N.; Walczewska-Szewc, K.; Shyng, S.-L.
10.1101/2024.09.05.611490 — biochemistry — Posted on 2024-09-05
4713 Kinesin-8 motors dimerize by folding their proximal tail domain into a compact helical bundle
Allingham, J. S.; Trofimova, D.; Doubleday, C.; Hunter, B.; Arevalo, J. D. S.; Davison, E.; Wen, E.; Munro, K.
10.1101/2024.09.05.611543 — biochemistry — Posted on 2024-09-05
4714 STRUCTURE-BASED DESIGN OF PROTACS FOR THE DEGRADATION OF SOLUBLE EPOXIDE HYDROLASE
Schoenfeld, J.; Brunst, S.; Ciomirtan, L.; Liebisch, N.; Kumar, A.; Ehrler, J.; Wintermeier, L.; Heering, J.; Brueggerhof, A.; Weizel, L.; Kahnt, A.; Schubert-Zsilavecz, M.; Knapp, S.; Fuerst, R.; Proschak, E.; Hiesinger, K.
10.1101/2024.09.05.611393 — biochemistry — Posted on 2024-09-05
4715 Dynamic and structural insights into allosteric regulation on MKP5 a dual-specificity phosphatase
Skeens, E.; Maschietto, F.; Ramu, M.; Shillingford, S.; Lolis, E. J.; Batista, V. S.; Bennett, A. M.; Lisi, G. P.
10.1101/2024.09.05.611520 — biochemistry — Posted on 2024-09-05
4716 A genome assembly and annotation for the Australian alpine skink Bassiana duperreyi using long-read technologies
Hanrahan, B. J.; Alreja, K.; Reis, A. L. M.; Chang, J. K.; Dissanayake, D. S. B.; Edwards, R. J.; Bertozzi, T.; Hammond, J. M.; O'Meally, D.; Deveson, I. W.; Georges, A.; Waters, P. D.; Patel, H. R.
10.1101/2024.09.05.611471 — genomics — Posted on 2024-09-05
4717 Neutralization and Stability of JN.1-derived LB.1, KP.2.3, KP.3 and KP.3.1.1 Subvariants
Li, P.; Faraone, J. N.; Hsu, C. C.; Chamblee, M.; Liu, Y.; Zheng, Y.-M.; Xu, Y.; Carlin, C.; Horowitz, J. C.; Mallampalli, R. K.; Saif, L. J.; Oltz, E. M.; Jones, D.; Li, J.; Gumina, R. J.; Bednash, J. S.; Xu, K.; Liu, S.-L.
10.1101/2024.09.04.611219 — molecular biology — Posted on 2024-09-05
4719 Mitochondrial topoisomerase I (Top1MT) prevents the onset of metabolic dysfunction-associated steatohepatitis (MASH) in mice
Baechler, S. A.; Saha, L. K.; Factor, V. M.; Chitinis, C.; Dhall, A.; Becker, D.; Marquardt, J. U.; Pommier, Y.
10.1101/2024.09.05.611454 — molecular biology — Posted on 2024-09-05
4720 Targeting Specific Kinase Substrates Rescues Increased Colitis Severity Induced by the Crohn's Disease-Linked LRRK2-N2081D Variant
Heaton, G. R.; Li, X.; Zhou, X.; Zhang, Y.; Vu, D. T.; Oeller, M.; Karayel, O.; Hoang, Q. Q.; Kars, M. E.; Wang, M.; Tarassishin, L.; Mann, M.; Peter, I.; Yue, Z.
10.1101/2024.09.05.611530 — molecular biology — Posted on 2024-09-05
4724 Emergence of resistance to the antiparasitic selamectin in Mycobacterium smegmatis is improbable and contingent on cell wall integrity
Ezquerra-Aznarez, J. M.; Gasparovic, H.; Chiner-Oms, A.; Quintana, A. L.; Blazquez, J.; Comas, I.; Kordulakova, J.; Ainsa, J. A.; Ramon-Garcia, S.
10.1101/2024.09.05.611451 — microbiology — Posted on 2024-09-05
4725 The Shigella flexneri effector IpaH1.4 facilitates RNF213 degradation and protects cytosolic bacteria against interferon-induced ubiquitylation
Saavedra Sanchez, L.; Dickinson, M. S.; Apte, S. S.; Zhang, Y.; De Jong, M.; Skavicusa, S.; Heaton, N. S.; Alto, N. M.; Coers, J.
10.1101/2024.09.05.611450 — microbiology — Posted on 2024-09-05
4728 Application of barcode sequencing to increase the throughput and complexity of Plasmodium falciparum genetic screening
Muwhezi, A.; Ghorbal, M.; Sanderson, T.; Ivanova, M.; Ansari, R.; Harper, S.; Wong, W.; Schulte, R.; Girling, G.; Schwach, F.; Bushell, E. S.; Beaver, C.; Billker, O.; Rayner, J. C.
10.1101/2024.09.05.611197 — microbiology — Posted on 2024-09-05
4730 Cryo-EM structure and polar assembly of the PS2 S-layer of Corynebacterium glutamicum
Sogues, A.; Sleutel, M.; Petit, J.; Megrian, D.; Bayan, N.; Wehenkel, A. M.; Remaut, H.
10.1101/2024.09.05.611363 — microbiology — Posted on 2024-09-05
4732 The Main protease (Mpro) from SARS-CoV-2 triggers plasma clotting in vitro by activating coagulation factors VII and FXII
Pagotto, A.; Uliana, F.; Nordio, G.; Pietrangelini, A.; Acquasaliente, L.; Macchia, M. L.; Bellanda, M.; Gatto, B.; De Silvestro, G.; Marson, P.; Simioni, P.; Picotti, P.; De Filippis, V.
10.1101/2024.09.05.611400 — biochemistry — Posted on 2024-09-05
4733 Nsp1 stalls DNA Polymerase alpha at DNA hairpins
Baranovskiy, A. G.; Morstadt, L. M.; Babayeva, N. D.; Tahirov, T. H.
10.1101/2024.09.03.608162 — biochemistry — Posted on 2024-09-05
4734 Structure and inhibition mechanisms of Mycobacterium tuberculosis essential transporterefflux protein A
Khandelwal, N. K.; Gupta, M.; Gomez, J. E.; Barkho, S.; Guan, Z.; Eng, A. Y.; Kawate, T.; Balasubramani, S. G.; Sali, A.; Hung, D. T.; Stroud, R. M.
10.1101/2024.09.04.611325 — biochemistry — Posted on 2024-09-05
4735 Genomic Epidemiology of SARS-CoV-2 in Norfolk, UK, March 2020 - December 2022
Hayles, E. H.; Page, A. J.; Guitian, J.; Kingsley, R. A.; The COVID-19 Genomics UK Consortium, ; Langridge, G. C.
10.1101/2024.09.05.611382 — genomics — Posted on 2024-09-05
4737 Computer vision guided rapid and precise automated cranial microsurgeries in rodents
Navabi, Z. S.; Peters, R.; Gulner, B.; Cherkkil, A.; Ko, E.; Dadashi, F.; O'Brien, J.; Feldkamp, M.; Kodandaramaiah, S. B.
10.1101/2024.09.03.611036 — neuroscience — Posted on 2024-09-05
4741 A flexible high-precision photoacoustic retinal prosthesis
Leong, A.; Li, Y.; Ruikes, T. R.; Voillot, J.; Yuan, Y.; Chen, G.; Facon, A.; Chhuon, C.-A.; Joffrois, C.; Tessier, G.; Cornebois, M.; Degardin, J.; Louise, J.-D.; Cheng, J.-X.; Yang, C.; Moulet, H.; Picaud, S.
10.1101/2024.09.03.611068 — neuroscience — Posted on 2024-09-05
4749 A "suicide" BCG strain provides enhanced immunogenicity and robust protection against Mycobacterium tuberculosis in macaques
Smith, A. A.; Su, H.; Wallach, J.; Liu, Y.; Maiello, P.; Borish, H. J.; Winchell, C.; Simonson, A. W.; Lin, P. L.; Rodgers, M.; Filmore, D. J.; Sakal, J.; Lin, K.; Vinette, V.; Schnappinger, D.; Ehrt, S.; Flynn, J. L.
10.1101/2023.11.22.568105 — immunology — Posted on 2024-09-05
4750 Multimodal MEG and microstructure-MRI investigations of the human hippocampal scene network
Read, M.-L.; Hodgetts, C. J.; Lawrence, A. D.; Evans, C. J.; Singh, K. D.; Umla-Runge, K.; Graham, K. S.
10.1101/2024.07.16.603546 — neuroscience — Posted on 2024-09-05
4752 Neural Basis of Number Sense in Larval Zebrafish
Luu, P.; Nadtochiy, A.; Zanon, M.; Moreno, N.; Messina, A.; Petrazzini, M. E. M.; Torres-Perez, J. V.; Jones, M.; Keomanee-Dizon, K.; Brennan, C. H.; Vallortigara, G.; Fraser, S. E.; Truong, T. V.
10.1101/2024.08.30.610552 — neuroscience — Posted on 2024-09-05
4753 GPRC6A as a novel kokumi receptor responsible for enhanced taste preferences by ornithine
Yamamoto, T.; Ueji, K.; Mizuta, H.; Inui-Yamamoto, C.; Kumamoto, N.; Shibata, Y.; Ugawa, S.
10.1101/2024.08.30.610470 — neuroscience — Posted on 2024-09-05
4757 Constructing well-defined neural networks of multiple cell types by picking and placing of neuronal spheroids using FluidFM
Vulic, K.; Connolly, S.; Zare-Eelanjegh, E.; Simonett, M.; Duru, J.; Ruff, T.; Clement, B. F.; Vörös, J.
10.1101/2024.09.03.610979 — neuroscience — Posted on 2024-09-05
4760 Decoupling Coldness and Softness in Tactile Wetness Perception Using Tunable Hydrogels
Becerra, L. L.; Root, N.; Clark, A.; Rafeedi, T.; Brown, W.; Chen, A. X.; Qie, Y.; Blau, R.; Miller, J.; Kapadia, K.; Ng, T. N.; Rouw, R.; Lipomi, D. J.
10.1101/2024.09.03.611060 — neuroscience — Posted on 2024-09-05
4761 Molecular, Cellular, and Developmental Organization of the Mouse Vomeronasal Organ at Single Cell Resolution
Hills, M. H.; Ma, L.; Fang, A.; Chiremba, T.; Malloy, S.; Scott, A. R.; Perera, A. G.; Yu, R.
10.1101/2024.02.22.581574 — neuroscience — Posted on 2024-09-05
4762 Single-shot detection of microscale tactile features
Reschechtko, S.; Pangan, W. R.; Zeinal Zadeh, R.; Pruszynski, J. A.
10.1101/2024.09.03.610877 — neuroscience — Posted on 2024-09-05
4763 Properties of Alzheimers disease brain-derived tau aggregates define tau processing by human astrocytes.
Reid, M. J.; Leija Salazar, M.; Troakes, C. P.; Lynham, S.; Srivastava, D. P.; Perez-Nievas, B.; Noble, W.
10.1101/2024.09.04.610753 — neuroscience — Posted on 2024-09-05
4767 3D Variable Analysis Reveal a Hidden Conformational Dynamics Controlling Ammonia Transport in Human Asparagine Synthetase
Coricello, A.; Nardone, A. J.; Gratteri, C.; Vos, M.; Chaptal, v.; Alcaro, S.; Zhu, W.; Takagi, Y.; Richards, N.
10.1101/2023.05.16.541009 — molecular biology — Posted on 2024-09-05
4770 Personalized Neuroimaging Reveals the Impact of Children's Interests on Language Processing in the Brain
Olson, H. A.; Johnson, K. T.; Nishith, S.; Frosch, I. R.; Gabrieli, J. D. E.; D'Mello, A. M.
10.1101/2023.03.21.533695 — neuroscience — Posted on 2024-09-05
4771 From tissue to subcellular level : imaging human precision-cut lung slices (PCLS) to gain insight into pandemic bacterial or viral infections
Eymieux, S.; Bull-Maurer, A.; Pichon, J.; Sizaret, D.; Maquart, M.; Carreras, F.; Saint-Vanne, M.; Doz-Deblauwe, E.; Bounab, B.; Lipan, B.; Handala, L.; Chesnel, F.; Burlaud-Gaillard, J.; Mammano, F.; Brand, D.; Legras, A.; Winter, N.; Remot, A.
10.1101/2024.09.04.611185 — cell biology — Posted on 2024-09-05
4773 The Aquaporin-4 expression and localization in the olfactory epithelium modulate the odorant-evoked responses and olfactory driven behavior
Lobraico, D.; Abbrescia, P.; Fioriello, M. G.; Barile, B.; Palazzo, C.; Valente, O.; Nicchia, G. P.; Dibattista, M.; Frigeri, A.
10.1101/2024.09.03.610981 — neuroscience — Posted on 2024-09-05
4775 Spatiotemporal dynamics of locomotor decisions in Drosophila melanogaster
Lebovich, L.; Alisch, T.; Redhead, E. S.; Parker, M. O.; Loewenstein, Y.; Couzin, I. D.; de Bivort, B. L.
10.1101/2024.09.04.611038 — animal behavior and cognition — Posted on 2024-09-05
4776 Ecological not social factors explain brain size in cephalopods: we need a new model for the evolution of big brains
Basava, K.; Bendixen, T.; Leonhard, A.; George, N. L.; Vanhersecke, Z.; Omotosho, J.; Mather, J.; Muthukrishna, M.
10.1101/2024.05.01.592020 — evolutionary biology — Posted on 2024-09-05
4777 The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence
Zhang, F.; Wang, Y.; Zhang, L.; Wang, C.; Chen, D.; Liu, H.; Xu, R.; Haynes, C. M.; Shim, J.-H.; Ge, X.
10.1101/2020.08.03.233874 — cell biology — Posted on 2024-09-05
4779 Single Cell MALDI-MSI Analysis of Lipids and Proteins within a Replicative Senescence Fibroblast Model
Sekera, E. R.; Rosas, L.; Holbrook, J. H.; Angeles-Lopez, Q. D.; Khaliullin, T.; Rojas, M.; Mora, A. L.; Hummon, A. B.
10.1101/2024.03.13.584140 — biochemistry — Posted on 2024-09-05
4780 Plasma membrane transporter Progressive Ankylosis Protein Homolog (ANKH/Ankh) mediates senescence-derived extracellular citrate and is regulated by DNA damage, inflammation and ageing
James, E. N.; Teh, M.-T.; Li, Y.; Wagner-bock, C.; Al-Khateeb, Z. F.; Karen-Ng, L. P.; Roberts, T.; Synchyshyn, L.; Lewis, A.; O'Loghlen, A.; Silver, A.; Michael-Titus, A. T.; Bennett, M.; Bundy, J. G.; Mycielska, M. E.; Parkinson, E. K.
10.1101/2024.08.30.609895 — cell biology — Posted on 2024-09-05
4781 MLX phosphorylation stabilizes the ChREBP-MLX heterotetramer on tandem E-boxes to control carbohydrate and lipid metabolism
Cadena del Castillo, C.; Deniz, O.; van Geest, F.; Rosseels, L.; Stockmans, I.; Robciuc, M.; Carpentier, S.; Wölnerhanssen, B.; Meyer-Gerspach, A. C.; Peterli, R.; Hietakangas, V.; Shimobayashi, M.
10.1101/2024.09.04.611172 — cell biology — Posted on 2024-09-05
4782 Dynamic Tracking of Native Precursors in Adult Mice
Liu, S.; Adams, S. E.; Zheng, H.; Ehnot, J.; Jung, S. K.; Jeffrey, G.; Menna, T.; Purton, L.; Lee, H.; Kurre, P.
10.1101/2024.04.02.587737 — cell biology — Posted on 2024-09-05
4783 Intra- and Inter-host Evolution of Human Norovirus in Healthy Adults
Ramani, S.; Javornik Cregeen, S. J.; Surathu, A.; Neill, F. H.; Muzny, D. M.; Doddapaneni, H.; Menon, V. K.; Hoffman, K. L.; Ross, M. C.; Metcalf, G.; Opekun, A. R.; Graham, D. Y.; Gibbs, R. A.; Petrosino, J. F.; Estes, M. K.; Atmar, R. L.
10.1101/2023.05.30.542907 — microbiology — Posted on 2024-09-05
4785 Accelerating protein engineering with fitness landscape modeling and reinforcement learning
Sun, H.; He, L.; Deng, P.; Liu, G.; Liu, H.; Cao, C.; Ju, F.; Wu, L.; Qin, T.; Liu, T.-Y.
10.1101/2023.11.16.565910 — synthetic biology — Posted on 2024-09-05
4786 Cancer associated fibroblast subtypes modulate the tumor-immune microenvironment and are associated with skin cancer malignancy
Forsthuber, A.; Aschenbrenner, B.; Korosec, A.; Jacob, T.; Annusver, K.; Krajic, N.; Kholodniuk, D.; Frech, S.; Zhu, S.; Purkhauser, K.; Lipp, K.; Werner, F.; Nguyen, V.; Griss, J.; Bauer, W.; Soler Cardona, A.; Weber, B.; Weninger, W.; Gesslbauer, B.; Staud, C.; Nedomansky, J.; Radtke, C.; Wagner, S. N.; Petzelbauer, P.; Kasper, M.; Lichtenberger, B. M.
10.1101/2023.05.03.539213 — cancer biology — Posted on 2024-09-05
4787 Immune cells employ intermittent integrin-mediated traction forces for 3D migration
Czerwinski, T.; Bischof, L.; Böhringer, D.; Kara, S.; Strissel, P. L.; Strick, R.; Winterl, A.; Gerum, R.; Wittmann, E.; Schneider, M.; Beckmann, M. W.; Nusser, G.; Wiesinger, M.; Budday, S.; Lux, A.; Voskens, C.; Fabry, B.; Mark, C.
10.1101/2023.04.20.537658 — biophysics — Posted on 2024-09-05
4789 Automatic crystal identification for crystallography: a comparison between direct methods and artificial intelligence strategies
Lages, C. F.; Nicoleti, V. Y.; Correa, M. R.; Mausbach, P.; Ramos, F. C.; de Araujo, E. A.; Nascimento, A. Z.; Miqueles, E. X.
10.1101/2024.08.22.609235 — bioinformatics — Posted on 2024-09-05
4790 Accelerated design of Escherichia coli genomes with reduced size using a whole-cell model and machine learning
Gherman, I. M.; Rees-Garbutt, J. P.; Pang, W.; Abdallah, Z. S.; Gorochowski, T. E.; Grierson, C. S.; Marucci, L.
10.1101/2023.10.30.564402 — bioengineering — Posted on 2024-09-05
4791 Frequent genetic exchanges revealed by a pan-mitogenome graph of a fungal plant pathogen
van Westerhoven, A.; Dijkstra, J.; Aznar Palop, L.; Wissink, K.; Bell, J.; Kema, G.; Seidl, M. F.
10.1101/2024.06.19.599757 — genomics — Posted on 2024-09-05
4792 Autophagy restricts fungal accommodation in the roots of Arabidopsis thaliana
Zecua-Ramirez, P.; Llamas, E.; Charura, N.; Dunken, N.; De Quattro, C.; Mandel, A.; Langen, G.; Dagdas, Y.; Zuccaro, A.
10.1101/2023.07.21.550010 — microbiology — Posted on 2024-09-05
4793 The partitioning of fatty acids between membrane and storage lipids controls ER membrane expansion.
Lysyganicz, P. K.; Barbosa, A. D.; Khondker, S.; Stewart, N. A.; Carman, G. M.; Stansfeld, P. J.; Dymond, M. K.; Siniossoglou, S.
10.1101/2024.09.05.611378 — cell biology — Posted on 2024-09-05
4794 MLX phosphorylation stabilizes the ChREBP-MLX heterotetramer on tandem E-boxes to control carbohydrate and lipid metabolism
Shimobayashi, M.; Cadena del Castillo, C.; Deniz, O.; van Geest, F.; Rosseels, L.; Stockmans, I.; Robciuc, M.; Carpentier, S.; Wölnerhanssen, B.; Meyer-Gerspach, A. C.; Peterli, R.; Hietakangas, V.
10.1101/2024.09.04.611172 — cell biology — Posted on 2024-09-05
4795 RTN4IP1 is essential for the final stages of mitochondrial complex I assembly and coenzyme Q biosynthesis
Olahova, M.; Guerra, R. M.; Collier, J. J.; Heidler, J.; Thompson, K.; White, C. R.; Castaneda-Tamez, P.; Cabrera-Orefice, A.; Lightowlers, R. N.; Chrzanowska-Lightowlers, Z. M. A.; Wittig, I.; Pagliarini, D. J.; Taylor, R. W.
10.1101/2024.09.04.610987 — cell biology — Posted on 2024-09-05
4796 Culture Conditions Differentially Regulate the Inflammatory Niche and Cellular Phenotype of Tracheo-Bronchial Basal Stem Cells
Murthy, S.; Seabold, D. A.; Gautam, L. K.; Caceres, A. M.; Sease, R.; Calvert, B. A.; Busch, S.; Neely, A.; Marconett, C. N.; Ryan, A. L.
10.1101/2024.09.04.611264 — cell biology — Posted on 2024-09-05
4797 Gigaxonin, mutated in Giant Axonal Neuropathy, interacts with TDP-43 and other RNA binding proteins
Phillips, C. L.; Faridounnia, M.; Battaglia, R. A.; Evangelista, B. A.; Cohen, T. J.; Opal, P.; Bouldin, T. W.; Armao, D.; Snider, N. T.
10.1101/2024.09.03.611033 — cell biology — Posted on 2024-09-05
4798 Mitochondrial transplantation: a novel therapy for liver ischemia/reperfusion injury
Mukkala, A. N.; David, B. A.; Ailenberg, M.; Liang, J.; Vaswani, C. M.; Karakas, D.; Goldfarb, R.; Barbour, W.; Gasner, A.; Wu, R. S.; Petrut, R.; Jerkic, M.; Andreazza, A.; dos Santos, C.; Ni, H.; Zhang, H.; Kapus, A.; Kubes, P.; Rotstein, O.
10.1101/2024.09.04.608457 — cell biology — Posted on 2024-09-05
4799 Extracellular vesicle bioactivity and potential clinical utility is determined by mesenchymal stromal cell clonal subtype
Ioannou, S.; Kay, A. G.; Stone, A. P.; Rand, E.; Elberfeld, S.; Bolton, W.; Larson, T.; Crossland, R. E.; Kehoe, O.; Mentlak, D. A.; Wang, X.-N.; MacDonald, C.; Genever, P.
10.1101/2024.09.05.609844 — cell biology — Posted on 2024-09-05
4800 RCC1 depletion drives protein transport defects and rupture in micronuclei
Zych, M. G.; Contreras, M.; Vashisth, M.; Mammel, A. E.; Ha, G.; Hatch, E. M.
10.1101/2024.09.04.611299 — cell biology — Posted on 2024-09-05
4801 Psoriasis-like inflammation induces mitochondrial function and structure changes in human keratinocytes and fibroblasts
Kulkoviene, G.; Uldukyte, M.; Haluts, S.; Kairyte, M.; Soliunas, J.; Salciute, V.; Morkuniene, R.; Jekabsone, A.
10.1101/2024.09.05.611357 — cell biology — Posted on 2024-09-05
4802 Zbtb38 inhibits apoptosis by transcriptionally regulating XIAP expression
Matsuda, E.; Shigeoka, T.; Nagaoka, H.; Nurulita, N. A.; Tada, S.; Ishida, Y.; Bessho, Y.
10.1101/2024.09.05.611337 — cell biology — Posted on 2024-09-05
4803 Pannexin 1 crosstalk with the Hippo pathway in malignant melanoma
Sayedyahossein, S.; Huang, K.; Zhang, C.; Karimi, M.; Bahmani, M.; O'Donnell, B. L.; Wakefield, B.; Li, Z.; Johnston, D.; Leighton, S.; Huver, M. S.; Dagnino, L.; Sacks, D. B.; Penuela, S.
10.1101/2024.09.03.611059 — cell biology — Posted on 2024-09-05
4804 Two functional forms of the Meckel-Gruber syndrome protein TMEM67 generated by proteolytic cleavage by ADAMTS9 mediate Wnt signaling and ciliogenesis
Ahmed, M.; Fischer, S.; Robert, K. L.; Lange, K. I.; Stuck, M. W.; Best, S.; Johnson, C. A.; Pazour, G. J.; Blacque, O. E.; Nandadasa, S.
10.1101/2024.09.04.611229 — cell biology — Posted on 2024-09-05
4805 Mechanosensing by Piezo1 regulates osteoclast differentiation via PP2A-Akt axis in periodontitis
Shindo, S.; Nakamura, S.; Hawthorne, A.; Heidari, A.; Pastore, M. R.; Okamoto, M.; Suzuki, M.; Salinas, M.; Minond, D.; Bontempo, A.; Cayabyab, M.; Yang, Y.; Crane, J. L.; Hernandez, M.; Vardar, S.; Hardigan, P.; Han, X.; Kaltman, S.; Kawai, T.
10.1101/2024.09.04.611049 — cell biology — Posted on 2024-09-05
4813 A snapshot of the Physcomitrella N-terminome reveals N-terminal methylation of organellar proteins
Hoernstein, S. N. W.; Schlosser, A.; Fiedler, K.; van Gessel, N.; Igloi, G. L.; Lang, D.; Reski, R.
10.1101/2024.06.11.598444 — plant biology — Posted on 2024-09-05
4814 HIF-1 activated by PIM1 assembles a pathological transcription complex and regulon that drives JAK2V617F MPN disease
Kealy, D.; Ellerington, R.; Bansal, S.; Zeng, A. G. X.; Medeiros, J. J. F.; West, K. A.; Blacknell, N.-M.; Hawley, C. A.; Lukaszonek, J.; Gawne, R.; Khoo, H. M.; Caalim, G.; Drylie, B.; Chatzigerou, J.; Rodriguez Lima Ferreira, B.; Wang, G.; Fielding, A. K.; Kent, D.; Psaila, B.; Wilkinson, A. C.; Holding, A. N.; Hitchcock, I. S.; Mason, A. S.; Gupta, V.; Dick, J.; Bridge, K. S.
10.1101/2024.07.02.601518 — cancer biology — Posted on 2024-09-05
4815 Cell cycle-dependent mRNA localization in P-bodies
SAFIEDDINE, A.; Benassy, M.-N.; Bonte, T.; Slimani, F.; Pourcelot, O.; Kress, M.; Ernoult-Lange, M.; Courel, M.; Coleno, E.; Imbert, A.; Laine, A.; Munier Godebert, A.; Vinit, A.; Blugeon, C.; Chevreux, G.; Gautheret, D.; Walter, T.; Bertrand, E.; Benard, M.; Weil, D.
10.1101/2024.04.16.589748 — cell biology — Posted on 2024-09-05
4816 Arc/Arg3.1 binds the nuclear polyadenylate-binding protein RRM and regulates neuronal activity-dependent formation of nuclear speckles
Kanhema, T.; Parobczak, K.; Patil, S.; Holm-Kaczmarek, D.; Hallin, E. I.; Ludwiczak, J.; Szczepankiewicz, A. A.; Pauzin, F. P.; Szum, A.; Ishizuka, Y.; dunin-horkawicz, S.; Kursula, P.; Wilczynski, G.; Magalska, A.; Bramham, C. R.
10.1101/2024.09.04.610023 — neuroscience — Posted on 2024-09-05
4817 Early life stress-induced miR-708-5p regulates mood disorder-associated behavioural phenotypes in mice and is a potential diagnostic biomarker for bipolar disorder
Gilardi, C.; Martins, H. C.; Lo Bianco, A.; Bicker, S.; Germain, P.-L.; Gross, F.; Sungur, A. O.; Kisko, T.; Stein, F.; Meinert, S.; Woehr, M.; Schwarting, R. K.; Dannlowski, U.; Kircher, T.; Schratt, G.
10.1101/2024.03.14.584977 — neuroscience — Posted on 2024-09-05
4821 Prenatal exposure to valproic acid induces sex-specific alterations in cortical and hippocampal neuronal structure and function in rats
Williams, O. O. F.; Coppolino, M.; Micelli, C. B.; McCallum, R. T.; Henry-Duru, P. T.; Manduca, J. D.; Lalonde, J.; Perreault, M. L.
10.1101/2024.09.03.611039 — neuroscience — Posted on 2024-09-05
4822 Genotype inference from aggregated chromatin accessibility data reveals genetic regulatory mechanisms
Wenz, B. M.; He, Y.; Chen, N.-C.; Pickrell, J. K.; Li, J. H.; Dudek, M. F.; Li, T.; Keener, R.; Voight, B. F.; Brown, C. D.; Battle, A.
10.1101/2024.09.04.610850 — genomics — Posted on 2024-09-05
4823 A robustly rooted tree of eukaryotes reveals their excavate ancestry.
Williamson, K.; Eme, L.; Banos, H.; McCarthy, C.; Susko, E.; Kamikawa, R.; Orr, R. J. S.; Munoz-Gomez, S. A.; Simpson, A. G. B.; Roger, A. J.
10.1101/2024.09.04.611237 — evolutionary biology — Posted on 2024-09-05
4824 Spike frequency adaptation in primate lateral prefrontal cortex neurons results from interplay between intrinsic properties and circuit dynamics
Koch, N. A.; Corrigan, B. W.; Feyerabend, M.; Gulli, R. A.; Jimenez-Sosa, M. S.; Abbass, M.; Sunstrum, J. K.; Matovic, S.; Roussy, M.; Luna, R.; Mestern, S. A.; Mahmoudian, B.; Vijayraghavan, S.; Igarashi, H.; Pradeepan, K. S.; Assis, W. J.; Pruszynski, J. A.; Tripathy, S.; Staiger, J. F.; Gonzalez-Burgos, G.; Neef, A.; Treue, S.; Everling, S.; Inoue, W.; Khadra, A.; Martinez-Trujillo, J. C.
10.1101/2024.09.03.610998 — neuroscience — Posted on 2024-09-05
4825 A conserved cell-type gradient across the human mediodorsal and paraventricular thalamus
Schulmann, A.; Feng, N.; Auluck, P. K.; Mukherjee, A.; Komal, R.; Leng, Y.; Gao, C.; Williams Avram, S. K.; Roy, S.; Usdin, T. B.; Xu, Q.; Imamovic, V.; Patel, Y.; Akula, N.; Raznahan, A.; Menon, V.; Roussos, P.; Duncan, L.; Elkahloun, A.; Singh, J.; Kelly, M. C.; Halassa, M. M.; Hattar, S.; Penzo, M. A.; Marenco, S.; McMahon, F.
10.1101/2024.09.03.611112 — neuroscience — Posted on 2024-09-05
4828 Brain-wide circuitry underlying altered auditory habituation in zebrafish models of autism.
Wilde, M.; Ghanbari, A.; Mancienne, T.; Moran, A.; Poulsen, R. E.; Constantin, L.; Lee, C.; Scholz, L. A.; Arnold, J.; Qin, W.; Karle, T. J.; Petrou, S.; Favre-Bulle, I. A.; Hoffman, E. J.; Scott, E. K.
10.1101/2024.09.04.611137 — neuroscience — Posted on 2024-09-05
4833 A PARP14/TARG1-Regulated RACK1 MARylation Cycle Drives Stress Granule Dynamics in Ovarian Cancer Cells
Challa, S.; Nandu, T.; Kim, H. B.; Gong, A.; Renshaw, C. W.; Li, W.-C.; Tan, X.; Aljardali, M. W.; Camacho, C. V.; Chen, J.; Kraus, W. L.
10.1101/2023.10.13.562273 — cell biology — Posted on 2024-09-04
4835 Dysregulation of Neuropilin-2 Expression in Inhibitory Neurons Impairs Hippocampal Circuit Development Leading to Autism-Epilepsy Phenotype
Subramanian, D.; Eisenberg, C.; Huang, A.; Baek, J.; Naveed, H.; Komatireddy, S.; Shiflett, M. W.; Tran, T. S.; Santhakumar, V.
10.1101/2024.02.05.578976 — neuroscience — Posted on 2024-09-04
4837 Resistance patterns in drug-adapted cancer cell lines reflect complex evolution in clinical tumors
Grimsley, H. E.; Antczak, M.; Reddin, I. G.; McLaughlin, K.-M.; Nist, A.; Mernberger, M.; Stiewe, T.; Fenton, T. R.; Speidel, D.; Harper-Wynne, C.; Cox, K.; Cinatl, J.; Wass, M. N.; Garrett, M.; Michaelis, M.
10.1101/2024.01.20.576412 — cancer biology — Posted on 2024-09-04
4839 The Interpretable Multimodal Machine Learning (IMML) framework reveals pathological signatures of distal sensorimotor polyneuropathy
Nguyen, P. B.; Garger, D.; Lu, D.; Maalmi, H.; Prokisch, H.; Thorand, B.; Adamski, J.; Kastenmueller, G.; Waldenberger, M.; Gieger, C.; Peters, A.; Suhre, K.; Boenhof, G. J.; Rathmann, W.; Roden, M.; Grallert, H.; Ziegler, D.; Herder, C.; Menden, M.
10.1101/2024.01.04.574164 — bioinformatics — Posted on 2024-09-04
4840 Deep contrastive learning enables genome-wide virtual screening
Jia, Y.; Gao, B.; Tan, J.; Hong, X.; Zhu, W.; Tan, H.; Xiao, Y.; Huang, Y.; Jin, Y.; Yuan, Y.; Tian, J.; Ma, W.; Zhang, Y.; Yan, C.; Zhang, W.; Lan, Y.
10.1101/2024.09.02.610777 — bioinformatics — Posted on 2024-09-04
4843 Unsupervised discovery of family specific vocal usage in the Mongolian gerbil
Peterson, R. E.; Choudhri, A.; Mitelut, C.; Tanelus, A.; Capo-Battaglia, A.; Williams, A. H.; Schneider, D. M.; Sanes, D. H.
10.1101/2023.03.11.532197 — animal behavior and cognition — Posted on 2024-09-04
4844 Current genomic deep learning architectures generalize across grass species but not alleles
Wrightsman, T.; Ferebee, T.; Romay, M. C.; Seetharam, A. S.; AuBuchon-Elder, T.; Phillips, A. R.; Syring, M.; Hufford, M. B.; Kellogg, E. A.; Buckler, E. S.
10.1101/2024.04.11.589024 — genomics — Posted on 2024-09-04
4848 Maternal obesity may disrupt offspring metabolism by inducing oocyte genome hyper-methylation via increased DNMTs
Chao, S.; Lu, J.; Li, L.-J.; Guo, H.-Y.; Xu, K.; Wang, N.; Zhao, S.-X.; Jin, X.-W.; Wang, S.-G.; Yin, S.; Shen, W.; Zhao, M.-H.; Huang, G.-A.; Sun, Q.-Y.; Ge, Z.-J.
10.1101/2024.04.24.590938 — developmental biology — Posted on 2024-09-04
4850 USP37 prevents premature disassembly of stressed replisomes by TRAIP
Kochenova, O. V.; D'Alessandro, G.; Pilger, D.; Schmid, E.; Richards, S. L.; Garcia, M. R.; Jhujh, S. S.; Voigt, A.; Gupta, V.; Carnie, C. J.; Wu, R. A.; Gueorguieva, N.; Stewart, G. S.; Walter, J. C.; Jackson, S. P.
10.1101/2024.09.03.611025 — molecular biology — Posted on 2024-09-04
4853 In-cell architecture of the mitochondrial respiratory chain
Waltz, F.; Righetto, R. D.; Zhang, X.; Kelley, R.; Obr, M.; Khavnekar, S.; Kotecha, A.; Engel, B. D.
10.1101/2024.09.03.610704 — molecular biology — Posted on 2024-09-04
4854 Description of a novel extremophile green algae, Chlamydomonas pacifica, and its potential as a biotechnology host
Dutra Molino, J. V.; Oliver, A.; Sethuram, H.; Kang, K.; Saucedo, B.; Diaz, C. J.; Gupta, A.; Jen, L. J.; Torres-tiji, Y.; Hidasi, N.; Badary, A.; Jenkins, H.; Fields, F. J.; Mayfield, S.
10.1101/2024.09.03.611117 — molecular biology — Posted on 2024-09-04
4857 2P-NucTag: on-demand phototagging for molecular analysis of functionally identified cortical neurons
Shi, J.; Nutkovich, B.; Kushinsky, D.; Rao, B. Y.; Herrlinger, S. A.; Tsivourakis, E.; Mihaila, T. S.; Malina, K. C.-K.; OToole, C. K.; Conde Paredes, M. E.; Yong, H. C.; Sanner, B. M.; Xie, A.; Varol, E.; Losonczy, A.; Spiegel, I.
10.1101/2024.03.21.586118 — neuroscience — Posted on 2024-09-04
4858 Genome-wide conditional degron libraries for functional genomics
Gameiro, E.; Juarez-Nunez, K. A.; Fung, J. J.; Shankar, S.; Luke, B.; Khmelinskii, A.
10.1101/2024.05.29.596381 — systems biology — Posted on 2024-09-04
4862 Crystal structure and catalytic mechanism of PL35 family glycosaminoglycan lyases with an ultrabroad substrate spectrum
Wei, L.; Cao, H.-Y.; Zou, R.; Du, M.; Zhang, Q.; Lu, D.; Xu, X.; Xu, Y.; Wang, W.; Chen, X.-L.; Zhang, Y.-Z.; Li, F.
10.1101/2024.09.04.611182 — biochemistry — Posted on 2024-09-04
4863 LEA_4 motifs function alone and in conjunction with synergistic cosolutes to protect a labile enzyme during desiccation
Nicholson, V.; Nguyen, K. H.; Gollub, E.; McCoy, M.; Yu, F.; Holehouse, A. S.; Sukenik, S.; Boothby, T. C.
10.1101/2024.09.04.611296 — biochemistry — Posted on 2024-09-04
4864 Dynamics in the Phytophthora capsici effector AVR3a11 confirm the core WY domain fold
Tolchard, J.; Chambers, V. S.; Boutemy, L. S.; Banfield, M. J.; Blumenschein, T. M. A.
10.1101/2024.09.04.611235 — biochemistry — Posted on 2024-09-04
4865 Correlative Imaging for Comprehensive Molecular Mapping of Individual Cell Types in Biological Tissues
Yang, M.; Iqfath, M.; Meke, F. N.; Qu, Z.; Hernly, E. L.; Su, P.; Zhang, Z.-Y.; Laskin, J.
10.1101/2024.09.04.611280 — biochemistry — Posted on 2024-09-04
4867 Characterization and bioinformatic filtering of ambient gRNAs in single-cell CRISPR screens using CLEANSER
Liu, S.; Hamilton, M. C.; Cowart, T. N.; Barrera, A.; Bounds, L. R.; Nelson, A. C.; Doty, R. W.; Allen, A. S.; Crawford, G. E.; Majoros, W. H.; Gersbach, C. A.
10.1101/2024.09.04.611293 — genomics — Posted on 2024-09-04
4868 Structural and molecular basis of the epistasis effect in enhanced affinity between SARS-CoV-2 KP.3 and ACE2
Feng, L.; Sun, Z.; Zhang, Y.; Jian, F.; Yang, S.; Yu, L.; Wang, J.; Shao, F.; Wang, X.; Cao, Y.
10.1101/2024.09.03.610799 — molecular biology — Posted on 2024-09-04
4871 Repurposing tRNA isodecoders for non-canonical functions via tRNA cleavage
Bhatter, N.; Advani, V. M.; Takenaka, Y.; Lyons, S. M.; Akiyama, Y.; Anderson, P. J.; Ivanov, P.
10.1101/2024.09.04.611212 — molecular biology — Posted on 2024-09-04
4872 Genome-Wide Mapping of RNA-Protein Associations via Sequencing
Qi, Z.; Xue, S.; Chen, J.; Zhao, W.; Johnson, K.; Wen, X.; Richard, J. L. C.; Zhong, S.
10.1101/2024.09.04.611288 — molecular biology — Posted on 2024-09-04
4876 E. coli associated with Crohn's disease exhibit distinct strategies to colonize macrophages
Bruder, E.; Nedjar, H.; Quenech'Du, N.; Chevarin, C.; Vazeille, E.; Granotier, M.; Singh, P.; Buisson, A.; Barnich, N.; Espeli, O.
10.1101/2024.09.04.611154 — microbiology — Posted on 2024-09-04
4881 Chemical genetic interactions elucidate pathways controlling tuberculosis antibiotic efficacy during infection
Oluoch, P. O.; Koh, E.-I.; Proulx, M. K.; Reames, C. J.; Papavinasasundaram, K.; Murphy, K. C.; Zimmerman, M.; Dartois, V. A.; Sassetti, C. M.
10.1101/2024.09.04.609063 — microbiology — Posted on 2024-09-04
4883 Bacterial metabolic remodelling by convergent evolution in response to host niche-dependent nutrient availability
Pickering, A.; Gorzynski, J.; Taylor-Joyce, G.; Fox, W.; Melo, P.; Alves, J.; Schlauch, H.; Sargison, F.; Yebra, G.; Fitzgerald, J. R.
10.1101/2024.09.04.611177 — microbiology — Posted on 2024-09-04
4885 Optimisation of a multiplexed, high throughput assay to measure neutralising antibodies against SARS-CoV-2 variants.
Ashley, C. L.; Bloul, M.; Alca, S.; Smith, L.; Jin, W.; Khoury, D.; Counoupas, C.; Davenport, M. P.; Triccas, J. A.; Steain, M.
10.1101/2024.09.01.610733 — immunology — Posted on 2024-09-04
4887 Genetic ancestry in Puerto Rican Afro-descendants illustrates diverse histories of African diasporic populations
Nieves-Colon, M. A.; Ulrich, E. C.; Chen, L.; Torres Colon, G. A.; Rivera Clemente, M.; La Corporacion Pinones Se Integra (COPI), ; Benn Torres, J.
10.1101/2024.09.02.610898 — genomics — Posted on 2024-09-04
4890 Neuronal autophagosomes are transported to astrocytes for degradation
Linda, K.; Schuurmans, I. M. E.; Smeenk, H.; Vints, K.; Negwer, M.; Peredo, N.; Lewerissa, E. I.; Swerts, J.; Hoekstra, M.; Mordelt, A.; Kuenen, S.; Gallego, S. F.; De Vrij, F. M.; Nadif Kasri, N.; Verstreken, P.
10.1101/2024.09.03.610698 — neuroscience — Posted on 2024-09-04
4892 Single-cell multiome uncovers differences in glycogen metabolism underlying species-specific speed of development
de la Porte, A.; Schröder, J.; Thomas, M.; Geuder, J.; Sterr, M.; Pastor, X.; Sanderson, L. E.; Barakat, T. S.; Enard, W.; Marr, C.; Schröter, C.; Drukker, M.
10.1101/2024.09.03.610938 — developmental biology — Posted on 2024-09-04
4893 Prophage regulation of Shewanella fidelis 3313 motility and biofilm formation: implications for gut colonization dynamics in Ciona robusta
Natarajan, O.; Gibboney, S. L.; Young, M. N.; Lim, S. J.; Nguyen, F.; Pluta, N.; Atkinson, C. G. F.; Leigh, B. A.; Liberti, A.; Kees, E. D.; Breitbart, M.; Gralnick, J. A.; Dishaw, L. J.
10.1101/2022.11.23.517592 — microbiology — Posted on 2024-09-04
4896 Heat stress sensitizes zebrafish embryos to neurological and cardiac toxicity.
Haapanen-Saaristo, A.-M.; Virtanen, N.; Tcarenkova, E.; Vaparanta, K. M.; Ampuja, M.; Vehniäinen, E.-R.; Paatero, I.
10.1101/2024.09.03.609146 — pharmacology and toxicology — Posted on 2024-09-04
4898 Pre and Post antibiotic epoch: insights into the historical spread of antimicrobial resistance
Cazares, A.; Figueroa, W.; Cazares, D.; Lima, L.; Turnbull, J. D.; McGregor, H.; Dicks, J.; Alexander, S.; Iqbal, Z.; Thomson, N.
10.1101/2024.09.03.610986 — genomics — Posted on 2024-09-04
4901 Distractor suppression operates exclusively in retinotopic coordinates
Ilksoy, Y. A.; van Moorselaar, D.; Wang, B.; Los, S. A.; Theeuwes, J.
10.1101/2024.02.01.578407 — neuroscience — Posted on 2024-09-04
4904 Multiomic Insights into Human Health: Gut Microbiomes of Hunter-Gatherer, Agropastoral, and Western Urban Populations
Singh, H.; Wiscovitch-Russo, R.; Kuelbs, C.; Espinoza, J.; Appel, A. E.; Lyons, R. J.; Vashee, S.; Fortsch, H. E. A.; Foster, J. E.; Ramdath, D.; Hayes, V. M.; Nelson, K. E.; Gonzalez-Juarbe, N.
10.1101/2024.09.03.611095 — genomics — Posted on 2024-09-04
4905 A workflow for practical training in ecological genomics using Oxford Nanopore long-read sequencing
Foster, R.; De Weerd, H.; Medd, N. C.; Booth, T.; Newman, C.; Ritch, H.; Santoyo-Lopez, J.; Trivedi, U.; Twyford, A. D.
10.1101/2024.09.03.610948 — genomics — Posted on 2024-09-04
4906 Evolution of drought resistance strategies following the introduction of white clover (Trifolium repens L.)
Hendrickson, B. T.; Stamps, C.; Patterson, C. M.; Strickland, H.; Foster, M. J.; Kim, A.; Kim, P.; Kooyers, N. J.
10.1101/2024.09.03.611023 — evolutionary biology — Posted on 2024-09-04
4907 Large-scale recovery in Costa Rica's Payment for Ecosystem Service Program
Delgado, G. L.; van den Hoogen, J.; Dent, D. H.; Bradfer Lawrence, T.; Werden, L. K.; Cole, R. J.; Diaz Quesada, C.; Jimenez Fajardo, J. A.; Mendez Rodriguez, A.; Mesen Solorzano, E.; Navarrete Chacon, G.; Coto, M.; Suarez Perez, I.; Vahlas, L.; Liang, Y.; Crowther, T. W.
10.1101/2024.09.03.610944 — ecology — Posted on 2024-09-04
4908 Differential splice isoforms of mouse CDK2 play functionally redundant roles during mitotic and meiotic division
Palmer, N.; Talib, S. Z. A.; Ow, J. R.; Tabaglio, T.; Goh, C. M. F.; Zhao, L. N.; Guccione, E.; Liu, K.; Kaldis, P.
10.1101/2024.09.03.610967 — cell biology — Posted on 2024-09-04
4909 Integrin-activating Yersinia protein Invasin sustains long-term expansion of primary epithelial cells as 2D organoid sheets
Wijnakker, J.; van Son, G.; Krueger, D.; van de Wetering, W.; Lopez Iglesias, C.; Schreurs, R.; van Rijt, F.; Lim, S.; Lin, L.; Peters, P. J.; Isberg, R. R.; Janda, C.; de Lau, w.; Clevers, H.
10.1101/2024.09.03.610788 — cell biology — Posted on 2024-09-04
4910 The chromatin reader Dido3 is a regulator of the gene network that controls B cell differentiation
Gutierrez del Burgo, F.; Garcia-Lopez, M. A.; Pons, T.; Vazquez de Luis, E.; Martinez-A, C.; Villares, R.
10.1101/2021.02.23.432411 — molecular biology — Posted on 2024-09-04
4911 Sex-specific differences in brain activity dynamics of youth with a family history of substance use disorder
Schilling, L. S.; Singleton, S. P.; Tozlu, C.; Hedo, M.; Zhao, Q.; Pohl, K. M.; Jamison, K. W.; Kuceyeski, A.
10.1101/2024.09.03.610959 — neuroscience — Posted on 2024-09-04
4913 Musical training does not enhance neural sound encoding at early stages of the auditory system: A large-scale multisite investigation
Whiteford, K. L.; Baltzell, L. S.; Chiu, M.; Cooper, J. K.; Faucher, S.; Goh, P. Y.; Hagedorn, A.; Irsik, V. C.; Irvine, A.; Lim, S.-J.; Mesik, J. L.; Mesquita, B.; Oakes, B.; Rajappa, N.; Roverud, E.; Schrlau, A. E.; Van Hedger, S. C.; Bharadwaj, H. M.; Johnsrude, I. S.; Kidd, G.; Luebke, A. E.; Maddox, R. K.; Marvin, E. W.; Perrachione, T. K.; Shinn-Cunningham, B. G.; Oxenham, A. J.
10.1101/2024.09.02.610856 — neuroscience — Posted on 2024-09-04
4917 Temporal Genomic Dynamics Shape Clinical Trajectory in Multiple Myeloma
MAURA, F.; Kaddoura, M. A.; Poos, A.; Baughn, L.; Ziccheddu, B.; Bartsch, M.-A.; Cirrincione, A.; Maclachlan, K. H.; Chojnacka, M.; Diamond, B.; Papadimitriou, M.; Blaney, P.; John, L.; Reichert, P.; Huhn, S.; Gagler, D.; Zhang, Y.; Dogan, A.; Lesokhin, A.; Davies, F.; Goldschmidt, H.; Fenk, R.; Weisel, K. C.; Mai, E. K.; Korde, N.; Morgan, G. J.; Rajkumar, V.; Usmani, S.; Landgren, O.; Raab, M.-S.; Weinhold, N.
10.1101/2024.08.30.610457 — cancer biology — Posted on 2024-09-04
4921 Caveolin assemblies displace one bilayer leaflet to organize and bend membranes
Doktorova, M.; Daum, S.; Ebenhan, J.; Neudorf, S.; Han, B.; Sharma, S.; Kasson, P.; Levental, K.; Bacia, K.; Kenworthy, A. K.; Levental, I.
10.1101/2024.08.28.610209 — biophysics — Posted on 2024-09-04
4922 In vivo Imaging and Pharmacokinetics of Percutaneously Injected Ultrasound and X-ray Imageable Thermosensitive Hydrogel loaded with Doxorubicin versus Free Drug in Swine
Delgado, J. F.; Negussie, A. H.; Varble, N. A.; Mikhail, A. S.; Arrichiello, A.; Borde, T.; Saccenti, L.; Bakhutashvili, I.; Morhard, R.; Owen, J. W.; Karanian, J. W.; Pritchard, W. F.; Wood, B. J.
10.1101/2024.09.01.610710 — bioengineering — Posted on 2024-09-04
4925 Cis-regulatory elements driving motor neuron-restricted viral payload expression within the mammalian spinal cord
Nagy, M. A.; Price, S.; Wang, K.; Gill, S. P.; Ren, E.; McElrath, L.; Pajak, V.; Deighan, S.; Liu, B.; Liu, X.; Diallo, A.; Lo, S.-C.; Kleiman, R.; Henderson, C.; Suh, J.; Griffith, E. C.; Greenberg, M. E.; Hrvatin, S.
10.1101/2024.09.02.610875 — neuroscience — Posted on 2024-09-04
4928 The sodium leak channel NALCN is regulated by neuronal SNARE complex proteins
Usher, S. G.; Toulme, E.; Florea, R.; Yatskevich, S.; Jao, C. C.; Colding, J. M.; Joshi, P.; Zilberleyb, I.; Trimbuch, T.; Brokowski, B.; Hauser, A. S.; Leitner, A.; Rosenmund, C.; Kschonsak, M.; Pless, S. A.
10.1101/2024.09.03.610923 — neuroscience — Posted on 2024-09-04
4929 Automated microinjection for zebrafish xenograft models
Ding, Y.; van der Kolk, K.-J.; van der Ent, W.; Scotto di Mase, M.; Kowald, S.; Huizing, J.; Vidal Teuton, J. M.; Mishra, G.; Kempers, M.; Almter, R.; Kunz, S.; Munier, L.; Koschmann, C.; Waszak, S. M.; Di Donato, V.; Dyballa, S.; ten Dijke, P.; Esguerra, C. V.; Jensen, L. D.; de Sonneville, J.
10.1101/2024.08.13.607596 — cancer biology — Posted on 2024-09-04
4930 The Role of Electron Spin-Polarizability and Charge Dynamics in Protein Function
Vyas, P.; Santra, K.; Preeyanka, N.; Gupta, A.; Weil-Ktorza, O.; Zhu, Q.; Longo, L. M.; Fransson, J.; Metanis, N.; Naaman, R.
10.1101/2023.11.16.567399 — biophysics — Posted on 2024-09-04
4931 M3NetFlow: A novel multi-scale multi-hop graph AI model for integrative multi-omic data analysis
Zhang, H.; Goedegebuure, P.; Ding, L.; Hawkins, W.; DeNardo, D.; Fields, R.; Chen, Y.; Li, F.
10.1101/2023.06.15.545130 — bioinformatics — Posted on 2024-09-04
4933 A hybrid approach to invertebrate biomonitoring using computer vision and DNA metabarcoding
Blair, J. D.; Weiser, M. D.; Siler, C. D.; Kaspari, M.; Smith, S. N.; McLaughlin, J. F.; Marshall, K. E.
10.1101/2024.09.02.610558 — bioinformatics — Posted on 2024-09-04
4934 Design of an Artificial Natural Killer Cell Mimicking System to Target Tumour Cells
Chugh, V.; K., V. K.; Quandt, D.; Kelly, S.; King, D.; Jensen, L.; Simpson, J.; Pandit, A.
10.1101/2024.09.02.610779 — bioengineering — Posted on 2024-09-04
4935 PROTON TRANSFER FROM BISPHENOL-A IS REQUIRED TO ACTIVATE EXTRANUCLEAR-INITIATED ESTROGEN RECEPTOR SIGNALING
Medina-Gali, R. M.; Martinez-Pinna, J.; Dos Santos, R. S.; Alonso-Magdalena, P.; Serrano-Maci, M.; Sempere-Navarro, R.; Soriano, S.; Fuentes-Paez, G.; Pasquali, L.; Mallavia, R.; Ciordia, S.; Grimaldi, M.; Balaguer, P.; Marroqui, L.; Nadal, A.
10.1101/2023.12.23.573228 — biochemistry — Posted on 2024-09-04
4936 Biological and genomic resources for the cosmopolitan phytoplankton Bathycoccus: Insights into genetic diversity and major structural variations
Dennu, L.; Devic, M.; Rigonato, J.; Falciatore, A.; Lozano, J.-C.; Verge, V.; Mariac, C.; Joli, N.; Jaillon, O.; Sabot, F.; Bouget, F.-Y.
10.1101/2023.10.16.562038 — genomics — Posted on 2024-09-04
4938 The cis-regulatory logic integrating spatial and temporal patterning in the vertebrate neural tube
Zhang, I.; Boezio, G. L.; Cornwall-Scoones, J.; Frith, T.; Jiang, M.; Howell, M.; Lovell-Badge, R.; Sagner, A.; Briscoe, J.; Delas, M. J.
10.1101/2024.04.17.589864 — developmental biology — Posted on 2024-09-04
4941 Multisensory approach in Mental Imagery: ALE meta-analyses comparing Motor, Visual and Auditory Imagery
Van Caenegem, E. E.; Moreno Verdu, M.; Waltzing, B.; Hamoline, G.; Mc Ateer, S.; Frahm, L.; Hardwick, R.
10.1101/2024.09.02.610739 — neuroscience — Posted on 2024-09-04
4942 Temporal proteomic and PTMomic atlas of cerebral organoid development
Elmkvist, S. B.; Bogetofte, H.; Jensen, P.; Jakobsen, L. A.; Havelund, J. F.; Ryding, M.; Brewer, J.; Faergeman, N. J.; Lancaster, M. A.; Larsen, M. R.
10.1101/2024.09.03.610941 — neuroscience — Posted on 2024-09-03
4943 Predictive Coding of Reward in the Hippocampus
Yaghoubi, M. H.; Nieto-Pasadas, A.; Mosser, C.-A.; Gisiger, T.; Wilson, E.; Williams, S.; Brandon, M. P.
10.1101/2024.09.03.611040 — neuroscience — Posted on 2024-09-03
4947 Single-cell multiome uncovers differences in glycogen metabolism underlying species-specific speed of development
de la Porte, A.; Schröder, J.; Thomas, M.; Geuder, J.; Sterr, M.; Pastor, X.; Enard, W.; Marr, C.; Schröter, C.; Drukker, M.
10.1101/2024.09.03.610938 — developmental biology — Posted on 2024-09-03
4949 Revealing the co-existence of written and spoken language coding neural populations in the left-ventral occipitotemporal cortex
Wang, S.; Dubarry, A.-S.; Chanoine, V.; Sein, J.; Anton, J.-L.; Nazarian, B.; Mercier, M. R.; Trebuchon, A.; Pattamadilok, C.
10.1101/2024.09.03.610932 — neuroscience — Posted on 2024-09-03
4952 Population genomics of Macrophomina spp. reveals cryptic host specialization and evidence for meiotic recombination
Pennerman, K. K.; Goldman, P.; Dilla-Ermita, C. J.; Ramos, G.; Jaime, J. H.; Lopez-Hernandez, J.; Ramos, J.; Aviles, M.; Borrero, C.; Gomez, A.; Neal, J.; Chilvers, M.; Ortiz, V.; Stukenbrock, E. H.; Goldman, G. H.; Mengistu, A.; Lopez-Nicora, H. D.; Sacher, G. O.; Vaghefi, N.; Kiss, L.; Benz, J. P.; Machado, A. R.; Seijo, T.; Peres, N.; Martin, F. N.; Broome, J.; Ivors, K.; Cole, G. S.; Knapp, S. J.; McFarlane, D. J.; Mattner, S. W.; Gambardella, M.; Henry, P. M.
10.1101/2024.09.03.609457 — genomics — Posted on 2024-09-03
4953 Long read sequencing and assembly of wild diploid relatives and cultivars in support of banana breeding programs
Chen, A.; Zhou, X.; Decker, K.; Havecker, E.; Du, Z.; Brown, A.; Aitken, E. A. B.; SHAH, T.; Uwimana, B.; Hresko, C.; Swennen, R.; Lowdon, R.
10.1101/2024.09.03.610537 — genomics — Posted on 2024-09-03
4955 Cell type specific suppression of hyper-recombination by human RAD18 is linked to PCNA K164 ubiquitination
Rogers, C. B.; Leung, W.; Baxley, R. M.; Kram, R. E.; Wang, L.; Buytendorp, J. P.; Le, K.; Largaespada, D. A.; Hendrickson, E. A.; Bielinsky, A. K.
10.1101/2024.09.03.611050 — molecular biology — Posted on 2024-09-03
4957 Identification of M-Sec as a unique cellular regulator of CSF-1 receptor activation
Abdelnaser, R. A.; Hiyoshi, M.; Takahashi, N.; Eltalkhawy, Y. M.; Mizuno, H.; Kimura, S.; Hase, K.; Ohno, H.; Monde, K.; Ono, A.; Suzu, S.
10.1101/2024.09.03.610939 — molecular biology — Posted on 2024-09-03
4959 Overcoming nucleotide bias in the nonenzymatic copying of RNA templates.
Duzdevich, D.; Carr, C. E.; Colville, B.; Aitken, H. R. M.; Szostak, J. W.
10.1101/2024.09.03.610991 — molecular biology — Posted on 2024-09-03
4961 Inner membrane protein OutB is covalently attached to peptidoglycan in the γ-proteobacterium Dickeya dadantii
Nicolai, X.; Liang, Y.; Ruaudel, F.; Narajczyk, M.; Czajkowski, R.; Rusconi, F.; Arthur, M.; Shevchik, V. E.
10.1101/2024.09.03.610988 — microbiology — Posted on 2024-09-03
4962 Malaria parasites undergo a rapid and extensive metamorphosis after invasion of the host erythrocyte
Freville, A.; Moreira-Leite, F.; Roussel, C.; Russell, M. R. G.; Fricot, A.; Carret, V.; Sissoko, A.; Hayes, M. J.; Dialo, A. B.; Kerkhoven, N.; Ressurreicao, M.; Dokmak, S.; Blackman, M.; Collinson, L.; Buffet, P. A.; Vaughan, S.; Ndour, A.; van Ooij, C.
10.1101/2024.09.03.610831 — microbiology — Posted on 2024-09-03
4963 Climate History and Metabolic Trade-offs shape the Bacterial Response to Drought
Bouskill, N.; Chacon, S.; Cusack, D.; Dietterich, L.; Chen, L.; Khurram, A.; Voriskova, J.; Holman, H.-Y.
10.1101/2024.09.03.611070 — microbiology — Posted on 2024-09-03
4965 Latent infection of an active giant endogenous virus in a unicellular green alga
Erazo-Garcia, M. P.; Sheyn, U.; Barth, Z. K.; Craig, R. J.; Wessman, P.; Jivaji, A. M.; Ray, W. K.; Svensson-Coelho, M.; Cornwallis, C. K.; Rengefors, K.; Brussaard, C. P. D.; Moniruzzaman, M.; Aylward, F. O.
10.1101/2024.09.03.611062 — microbiology — Posted on 2024-09-03
4967 INCOMPATIBILITY GROUPS OF PSEUDOMONAS PLASMIDS REVISITED: COMPREHENSIVE ANALYSIS OF R-FACTORS AND THEIR REPLICONS
Nishimura, Y.; Kaneko, K.; Kamijo, T.; Isogai, N.; Tokuda, M.; Xie, H.; Tsuda, Y.; Hirabayashi, A.; Moriuchi, R.; Dohra, H.; Kimbara, K.; Suzuki-Minakuchi, C.; Nojiri, H.; Suzuki, H.; Suzuki, M.; Shintani, M.
10.1101/2024.09.03.610885 — microbiology — Posted on 2024-09-03
4968 Fc-dependent protective efficacy of non-inhibitory antibodies targeting influenza A virus neuraminidase is limited by epitope availability
Pascha, M. N.; Ballegeer, M.; van Haperen, R.; Kooij, A. C.; van Miltenburg, D. M.; Smits, A. A.; Schipper, J. G.; Cui, H.; Albulescu, I. C.; Bosch, B. J.; Grosveld, F.; Saelens, X.; Drabek, D.; de Haan, C.
10.1101/2024.09.03.611041 — microbiology — Posted on 2024-09-03
4970 A Third COVID-19 Vaccine Dose in Kidney Transplant Recipients Induces Antibody Response to Vaccine and Omicron Variants but Shows Limited Ig Subclass Switching
Lee, J. M.; Sachithanandham, J.; Lee, J. S.; Shapiro, J. R.; Li, M.; Sitaris, I.; Peralta, S. R.; Wouters, C.; Cox, A. L.; Segev, D. L.; Durand, C. M.; Robien, M.; Tobian, A. A. R.; Karaba, A. H.; Blankson, J. N.; Werbel, W. A.; Pekosz, A.; Klein, S. L.
10.1101/2024.09.01.610689 — immunology — Posted on 2024-09-03
4973 High-throughput DNA engineering by mating bacteria
Matsui, T.; Hung, P.-H.; Mei, H.; Liu, X.; Li, F.; Collins, J.; Li, W.; Miller, D.; Wilson, N.; Toro, E.; Taghon, G. J.; Sherlock, G. J.; Levy, S.
10.1101/2024.09.03.611066 — synthetic biology — Posted on 2024-09-03
4976 LPA3 receptors have orthosteric and allosteric binding sites evidenced under docking studies.
Solis, K. H.; Romero-Avila, M. T.; Rincon-Heredia, R.; Correa-Basurto, J.; SAINZ, J. A. G.
10.1101/2024.09.03.611107 — biochemistry — Posted on 2024-09-03
4984 Performance of qpAdm-based screens for genetic admixture on admixture-graph-shaped histories and stepping-stone landscapes
Flegontova, O.; Isıldak, U.; Yüncü, E.; Williams, M. P.; Huber, C. D.; Koci, J.; Vyazov, L. A.; Changmai, P.; Flegontov, P.
10.1101/2023.04.25.538339 — genetics — Posted on 2024-09-03
4985 Short-term fluctuating and long-term divergent selection on sympatric Monkeyflowers: insights from decade-spanning reciprocal transplants
Dong, C. M.; Aponte Rolon, B. A.; Sullivan, J. K.; Tataru, D.; Deleon, M.; Dennis, R.; Dutton, S.; Machado Perez, F. J.; Montano, L.; Ferris, K. G.
10.1101/2024.06.26.600870 — evolutionary biology — Posted on 2024-09-03
4987 Integrator complex subunit 12 knockout overcomes a transcriptional block to HIV latency reversal
Gray, C. N.; Ashokkumar, M.; Janssens, D. H.; Kirchherr, J. L.; Allard, B.; Hsieh, E.; Hafer, T. L.; Archin, N. M.; Browne, E. P.; Emerman, M.
10.1101/2024.08.30.610517 — microbiology — Posted on 2024-09-03
4988 Hierarchy between forelimb premotor and primary motor cortices and its manifestation in their firing patterns
Saiki-Ishikawa, A.; Agrios, M.; Savya, S.; Forrest, A.; Sroussi, H.; Hsu, S.; Basrai, D.; Xu, F.; Miri, A.
10.1101/2023.09.23.559136 — neuroscience — Posted on 2024-09-03
4992 mosGraphFlow: a novel integrative graph AI model mining disease targets from multi-omic data
Zhang, H.; Cao, D.; Xu, T.; Chen, E.; Li, G.; Chen, Y.; Payne, P.; Province, M.; Li, F.
10.1101/2024.08.01.606219 — bioinformatics — Posted on 2024-09-03
4994 Cryptic endogenous retrovirus subfamilies in the primate lineage
Chen, X.; Zhang, Z.; Yan, Y.; Goubert, C.; Bourque, G.; Inoue, F.
10.1101/2023.12.07.570592 — genomics — Posted on 2024-09-03
4995 The Impact of a Natural Ingredients based Intervention Targeting the Nine Hallmarks of Aging on DNA methylation
Carreras-Gallo, N.; Dargham, R.; Thorpe, S.; Warren, S.; Mendez, T. L.; Smith, R.; Macpherson, G.; Dwaraka, V. B.
10.1101/2024.09.02.610828 — genomics — Posted on 2024-09-03
4996 Examining intra-host genetic variation of RSV by short read high-throughput sequencing
Henke, D. M.; Piedra, F.-A.; Avadhanula, V.; Doddapaneni, H. V.; Muzny, D. M.; Menon, V.; Hoffman, K.; Ross, M. C.; Javornik Cregeen, S. J.; Metcalf, G.; Gibbs, R. A.; Petrosino, J. F.; Piedra, P.
10.1101/2023.05.17.541198 — genomics — Posted on 2024-09-03
4999 Spinal neural tube formation and tail development in human embryos
Santos, C.; Marshall, A. R.; Murray, A.; Metcalfe, K.; Narayan, P.; de Castro, S. C. P.; Maniou, E.; Greene, N. D. E.; Galea, G. L.; Copp, A. J.
10.1101/2023.07.18.549464 — developmental biology — Posted on 2024-09-03
5000 Circular RNAs correlate with DNA damage in ageing human placental tissue and in stillbirth
Arthurs, A. L.; Jackson, M. R.; McCullough, D.; SCOTT, H.; Barnett, C. P.; Webb, S. T.; Smith, M. D.; Jankovic-Karasoulos, T.; Dekker, G. A.; Roberts, C. T.
10.1101/2024.09.02.610398 — molecular biology — Posted on 2024-09-03
5002 The sodium leak channel NALCN is regulated by neuronal SNARE complex proteins
Usher, S. G.; Toulme, E.; Florea, R.; Yatskevich, S.; Jao, C. C.; Colding, J. M.; Joshi, P.; Zilberleyb, I.; Trimbuch, T.; Brokowski, B.; Hauser, A. S.; Rosenmund, C.; Kschonsak, M.; Pless, S. A.
10.1101/2024.09.03.610923 — neuroscience — Posted on 2024-09-03
5004 Electrophysiological correlates of lucid dreaming: sensor and source level signatures
Demirel, C.; Gott, J.; Appel, K.; Lueth, K.; Fischer, C.; Raffaelli, C.; Westner, B.; Wang, X.; Zavecz, Z.; Steiger, A.; Erlacher, D.; LaBerge, S.; Mota-Rolim, S.; Ribeiro, S.; Zeising, M.; Adelhoefer, N.; Dresler, M.
10.1101/2024.04.09.588765 — neuroscience — Posted on 2024-09-03
5005 Estradiol elicits distinct firing patterns in arcuate nucleus kisspeptin neurons of females through altering ion channel conductances
Qiu, J.; Voliotis, M.; Bosch, M. A.; Li, X. F.; Zweifel, L. S.; Tsaneva-Atanasova, K.; O'Byrne, K.; Ronnekleiv, O. K.; Kelly, M. J.
10.1101/2024.02.20.581121 — neuroscience — Posted on 2024-09-03
5006 Democratizing access to microfluidics: Rapid prototyping of open microchannels with low-cost LCD 3D printers
Leong, K. M.; Sun, A. Y.; Quach, M. L.; Lin, C. H.; Craig, C. A.; Guo, F.; Robinson, T. R.; Chang, M. M.; Olanrewaju, A. O.
10.1101/2023.09.26.558021 — scientific communication and education — Posted on 2024-09-03
5007 Partial redundancy buffers deleterious effects of mutating DNA methyltransferase 1-1 (MET1-1) in polyploid wheat
Burrows, S.; Dorussen, D.; Crudgington, J.; Di Santolo, G.; Simmonds, J.; Catoni, M.; Borrill, P.
10.1101/2024.07.26.605257 — plant biology — Posted on 2024-09-03
5009 Setting up an institutional OMERO environment for bioimage data: perspectives from both facility staff and users
Jannasch, A. K.; Tulok, S.; Okafornta, C. W.; Kugel, T.; Bortolomeazzi, M.; Boissonnet, T.; Schmidt, C.; Vogelsang, A.; Dittfeld, C.; Tugtekin, S.-M.; Matschke, K. E.; Paliulis, L.; Thomas, C.; Lindemann, D.; Fabig, G.; Mueller-Reichert, T.
10.1101/2024.07.04.601832 — bioinformatics — Posted on 2024-09-03
5010 HALO: Hierarchical Causal Modeling for Single Cell Multi-Omics Data
Mao, H.; Jia, M.; Di, M.; Valenzi, E.; Cai, X. T.; Singh, H.; Lafyatis, R. A.; Zhang, K.; Benos, P. V.
10.1101/2022.10.17.512602 — bioinformatics — Posted on 2024-09-03
5016 Novel Role of Endothelial CD45 in Regulating Endothelial-to-Mesenchymal Transition in Atherosclerosis
Peng, Q.; Arulsamy, K.; Lu, Y. W.; Wu, H.; Zhu, B.; Singh, B.; Cui, K.; Wylie-Sears, J.; Li, K. S.; Wong, S.; Cowan, D. B.; Aikawa, M.; Chen, K.; Wang, D.-Z.; Bischoff, J.; Chen, H.
10.1101/2024.09.03.610974 — cell biology — Posted on 2024-09-03
5017 LL-37 modulates IL-17A/F-mediated airway inflammation by selectively suppressing Lipocalin-2.
Altieri, A.; Lloyd, D.; Ramotar, P.; van der Does, A. M.; Hemshekhar, M.; Mookherjee, N.
10.1101/2024.09.03.610924 — immunology — Posted on 2024-09-03
5018 Cortistatin exerts an immunomodulatory and neuroprotective role in a preclinical model of ischemic stroke
Castillo-Gonzalez, J.; Buscemi, L.; Vargas-Rodriguez, P.; Serrano-Martinez, I.; Forte-Lago, I.; Price-Hirt, M.; Hernandez-Cortes, P.; Hirt, L.; Gonzalez-Rey, E.
10.1101/2024.02.07.579281 — immunology — Posted on 2024-09-03
5021 The role of RNA in the nanoscale organization of alpha-synuclein phase separation
Zappone, S.; Perego, E.; Rupert, J.; Zacco, E.; Slenders, E.; Tartaglia, G. G.; Vicidomini, G.
10.1101/2024.09.03.610813 — biophysics — Posted on 2024-09-03
5023 PROTON TRANSFER FROM BISPHENOL-A IS REQUIRED TO ACTIVATE EXTRANUCLEAR-INITIATED ESTROGEN RECEPTOR SIGNALING
Medina-Gali, R. M.; Martinez-Pinna, J.; Dos Santos, R. S.; ALONSO-MAGDALENA, P.; Serrano-Maci, M.; Sempere-Navarro, R.; Soriano, S.; Fuentes-Paez, G.; Pasquali, L.; Mallavia, R.; Ciordia, S.; Grimaldi, M.; Balaguer, P.; Marroqui, L.; Nadal, A.
10.1101/2023.12.23.573228 — biochemistry — Posted on 2024-09-03
5026 The Impact of a Natural Ingredients based Intervention Targeting the Nine Hallmarks of Aging on DNA methylation
Carreras-Gallo, N.; Dargham, R.; Thorpe, S.; Warren, S.; Mendez, T. L.; Smith, R.; Dwaraka, V. B.
10.1101/2024.09.02.610828 — genomics — Posted on 2024-09-03
5030 Identification of nuclear pore proteins at plasmodesmata
Schladt, T. M.; Ejike, J. O.; Miras, M.; Engelhorn, J.; Pottier, M.; Dickmanns, M.; Xi, L.; Puetz, N.; Dalal, A.; Restrepo, A.; Gombos, S.; Haensch, S.; Nakamura, M.; Gao, C.; Lange, R.; Simon, R.; Schulze, W. X.; Frommer, W. B.
10.1101/2024.09.02.610746 — cell biology — Posted on 2024-09-03
5031 Histone serves as an eat-me signal to induce RAGE-mediated phagocytosis
Li, Y.; Zhou, X.; Yang, Y.; Du, C.; Liu, Y.-S.; Li, Z.; Nakanishi, H.
10.1101/2024.09.03.610921 — cell biology — Posted on 2024-09-03
5032 A FUCCI sensor reveals complex cell cycle organization of Toxoplasma endodyogeny
Batra, M.; Marsilia, C.; Awshah, D.; Hawkins, L. M.; Wang, C.; Chaput, D.; Naumova, D. A.; Suvorova, E. S.
10.1101/2024.09.02.610821 — cell biology — Posted on 2024-09-03
5033 USP37 prevents unscheduled replisome unloading through MCM complex deubiquitination
Bolhuis, D.; Fleifel, D.; Bonacci, T.; Wang, X.; Mouery, B.; Cook, J.; Brown, N.; Emanuele, M.
10.1101/2024.09.03.610997 — cell biology — Posted on 2024-09-03
5034 A paleogenomic approach to reconstruct historical responses of coral reefs to anthropogenic change
Gonzalez-Pech, R. A.; Howe, C.; Lizcano-Sandoval, L. D.; Eisenhofer-Philipona, R. A.; Marciniak, S.; Roitman, S.; Marulanda-Gomez, A. M.; Rodriguez-Ramirez, A.; Perry, G.; Weyrich, L.; Lopez-Victoria, M.; Cole, J. E.; Medina, M.
10.1101/2024.09.02.610915 — molecular biology — Posted on 2024-09-03
5035 Directed disruption of IL2 aggregation sites produces designer biologics with enhanced specificity coupled to improved production capacity
Dashwood, A. J.; Makuyana, N.; van der Kant, R.; Ghodsinia, A.; Hernandez, A. R.; Lienart, S.; Burton, O.; Dooley, J.; Ali, M.; Kouser, L.; Naranjo, F.; Holt, M. G.; Rousseau, F.; Schymkowitz, J.; Liston, A.
10.1101/2024.09.02.610760 — immunology — Posted on 2024-09-03
5037 Long-term Tolerance to Islet Transplantation via Targeted Reduction of beta cell-specific T cells.
Kotliar, M.; Cianciolo, E. E.; Pham, D. H.; Carroll, K.; Barski, A.; Jordan, M. B.; Katz, J.
10.1101/2024.09.02.610863 — immunology — Posted on 2024-09-03
5039 Keratinocyte-derived exosomes in painful diabetic neuropathy
Coy-Dibley, J.; Jayaraj, N. D.; Ren, D.; Pacifico, P.; Belmadni, A. A.; Wang, Y.-Z.; Gebis, K. K.; Savas, J. N.; Paller, A. S.; Miller, R. J.; Menichella, D. M.
10.1101/2024.08.21.608803 — neuroscience — Posted on 2024-09-03
5040 Pharmacological blockade of glutamatergic input to the lateral habenula modulates consumption of palatable diet components in male Wistar rats
Slomp, M.; Spitters, M. T.; van Bergen, J. L.; van Irsen, A. A. S.; Kool, T.; Eggels, L.; Mul, J. D.; la Fleur, S. E.
10.1101/2024.09.02.610523 — neuroscience — Posted on 2024-09-03
5042 The mitochondrial unfolded protein response promotes senescence in human microglia by increasing S-adenosylmethionine availability for polyamine synthesis.
Perez Jimenez, M. J.; Bertoli, F.; Raji, H.; Lam, A.; Bosch, M.; Weissleder, C.; Nemazanyy, I.; Kalb, S.; Hirschberg, I.; Brunetti, D.; Heckenbach, I.; Scheibye-Knudsen, M.; Deleidi, M.
10.1101/2024.09.03.610925 — neuroscience — Posted on 2024-09-03
5044 Pvf1-PvR-mediated crosstalk between the trachea and the gut guides intestinal stem cell migration to promote gut regeneration.
MacKay, D. J.; John, A.; Christensen, C. F.; Loudhaief, R.; Tanari, A. B.; Rauzi, M.; Colombani, J.; Andersen, D. S.
10.1101/2024.09.02.609652 — physiology — Posted on 2024-09-03
5047 HLA-E and NKG2A Mediate Resistance to M. bovis BCG Immunotherapy in Non-Muscle-Invasive Bladder Cancer
Ranti, D.; Yu, H.; Wang, Y.; Bieber, C.; Strandgaard, T.; Salome, B.; Houghton, S.; Kim, J.; Ravichandran, H.; Okulate, I.; Merritt, E.; Bang, S.; Demetriou, A.; Li, Z.; Lindskrog, S. V.; Ruan, D. F.; Daza, J.; Rai, R.; Hegewisch-Solloa, E.; Mace, E.; Fernandez-Rodriguez, R.; Izadmehr, S.; Doherty, G.; Farkas, A.; Cruz-Encarnacion, P.; Shroff, S.; Patel, F.; Tran, M.; Park, J.; Qi, J.; Patel, M.; Geanon, D.; Kelly, G.; de Real, R.; Lee, B.; Nie, K.; Miake-Lye, S.; Angeliadis, K.; Radkevich, E.; Thin, T. H.; Garcia-Barros, M.; Brown, H.; Martin, B.; Mateo, A.; Soto, A.; Sussman, R.; Shiwlani, S
10.1101/2024.09.02.610816 — cancer biology — Posted on 2024-09-03
5049 Continuous self-repair protects vimentin intermediate filaments from fragmentation
Tran, Q. D.; Lenz, M.; Wioland, H.; JEGOU, A.; Romet-Lemonne, G.; Leduc, C.
10.1101/2024.09.02.610785 — biophysics — Posted on 2024-09-03
5051 A hybrid approach to invertebrate biomonitoring using computer vision and DNA metabarcoding
Blair, J. D.; Weiser, M. D.; Siler, C. D.; Kaspari, M.; Smith, S. N.; McLaughlin, J. F.; Marshall, K. E.
10.1101/2024.09.02.610558 — bioinformatics — Posted on 2024-09-03
5052 Benchmarking Protein Language Models for Protein Crystallization
Mall, R.; Kaushik, R.; Martinez, Z. A.; Thomson, M.; Castiglione, F.
10.1101/2024.09.02.610758 — bioinformatics — Posted on 2024-09-03
5053 Deep contrastive learning enables genome-wide virtual screening
Jia, Y.; Gao, B.; Tan, J.; Hong, X.; Zhu, W.; Tan, H.; Xiao, Y.; Huang, Y.; Jin, Y.; Yuan, Y.; Tian, J.; Ma, W.; Zhang, Y.; Yan, C.; Zhang, W.; Lan, Y.
10.1101/2024.09.02.610777 — bioinformatics — Posted on 2024-09-03
5054 Experimental method for creating skin with acquired appendage dysfunction
Moriwaki, Y.; Shiraishi, M.; Shen, Q.; Du, Z.; Okazaki, M.; Kurita, M.
10.1101/2024.09.02.610845 — bioengineering — Posted on 2024-09-03
5055 KegAlign: Optimizing pairwise alignments with diagonal partitioning
Gulhan, B.; Burhans, R.; Harris, R.; Kandemir, M.; Haeussler, M.; Nekrutenko, A.
10.1101/2024.09.02.610839 — genomics — Posted on 2024-09-03
5057 Constructing a Draft Indian Cattle Pangenome Using Short-Read Sequencing
Azam, S.; Sahu, A.; Pandey, N. K.; Neupane, M.; Tassell, C. P. V.; Rosen, B. D.; Gandham, R. K.; Rath, S. N.; Majumdar, S. S.
10.1101/2024.09.02.610916 — genomics — Posted on 2024-09-03
5058 A new Betaflexivirus species in Ferraria crispa plants
Dekker, R. J.; de Leeuw, W. C.; van Olst, M.; Ensink, W. A.; van Leeuwen, S.; Breit, T. M.; Jonker, M. J.
10.1101/2024.09.02.610804 — genomics — Posted on 2024-09-03
5059 Mitochondrial direct repeat reduction as a strategy for enhancing human longevity: the case of the common repeat
Shamanskiy, V. A.; Gunbin, K. V.; Tretiakov, E. O.; Mazunin, I. O.; Skripskaya, V.; Mihailova, A. A.; Mikhailova, A. G.; Ree, N.; Timonina, V.; Knorre, D.; Kunz, W. S.; Okada, Y.; Fiorell, N.; Reymond, A.; Bazykin, G. A.; Fellay, J.; Tanaka, M.; Khrapko, K.; Popadin, K.
10.1101/2024.09.02.610808 — genetics — Posted on 2024-09-03
5061 Within-host competition sparks pathogen molecular evolution and perpetual microbiota dysbiosis.
Stevens, E. J.; Li, J. D.; Hector, T. E.; Drew, G. C.; Hoang, K.; Greenrod, S. T.; Paterson, S.; King, K. C.
10.1101/2024.09.03.610829 — evolutionary biology — Posted on 2024-09-03
5062 Unraveling genetic load dynamics during biological invasion: insights from two invasive insect species
Lombaert, E.; Blin, A.; Porro, B.; Guillemaud, T.; Bernal, J. S.; Chang, G.; Kirichenko, N.; Sappington, T. W.; Toepfer, S.; Deleury, E.
10.1101/2024.09.02.610743 — evolutionary biology — Posted on 2024-09-03
5064 Mating strategies explain sex-biased infections in an emerging fungal disease
Kailing, M. J.; Hoyt, J. R.; White, J. P.; Redell, J. A.; Kaarakka, H. M.; Langwig, K. E.
10.1101/2024.09.02.609945 — ecology — Posted on 2024-09-03
5066 Wnt5a and Notum Influence the Temporal Dynamics of Cartilaginous Mesenchymal Condensations in Developing Trachea.
Bottasso-Arias, N.; Mohanakrishnan, M.; Trovillion, S.; Burra, K.; Russell, N.; Wu, Y.; Xu, Y.; Sinner, D. I.
10.1101/2024.09.02.610014 — developmental biology — Posted on 2024-09-03
5068 CIZ1 regulates G1 length and the CDK threshold for initiation of DNA replication to prevent DNA replication stress
Tollitt, J.; Briggs, T.; Allinson, S. L.; Parsons, J. L.; Staples, C. J.; Mort, R.; Copeland, N. A.
10.1101/2024.09.02.610838 — cell biology — Posted on 2024-09-03
5070 ApoE4 disrupts intracellular trafficking and iron homeostasis in an improved iPSC-based model of human brain endothelial cells
Bell, L.; Stokar-Regenscheit, N.; Simonneau, C.; Augustin, A.; Höllbacher, B.; D'Abate, L.; Ficek-Pascual, J.; Schneider, K.; Von Tell, D.; Zanini, C.; Zundel, C.; Golling, S.; Becker, C.; Odermatt, A.; Pigoni, M.; Villasenor, R.
10.1101/2024.09.03.610802 — cell biology — Posted on 2024-09-03
5071 Temporal control of acute protein aggregate turnover by UBE3C and NRF1-dependent proteasomal pathways
Hickey, K. L.; Panov, A.; Whelan, E. M.; Schaefer, T.; Mizrak, A.; Kopito, R. R.; Baumeister, W.; Fernandez-Busnadiego, R.; Harper, W.
10.1101/2024.08.30.610524 — cell biology — Posted on 2024-09-03
5073 β-glucan reprograms alveolar macrophages via neutrophil/IFNγ axis to promote lung injury
Prevel, R.; Pernet, E.; Tran, K. A.; Sadek, A.; Sadeghi, M.; Lapshina, E.; Jurado, L.; Kristof, A. S.; Moumni, M.; Poschmann, J.; Divangahi, M.
10.1101/2024.09.02.610842 — immunology — Posted on 2024-09-03
5074 β-Glucan Reprograms Neutrophils to Induce Disease Tolerance Against Influenza A Virus
Khan, N.; Chevre, R.; Sun, S. J.; Sadeghi, M.; Pernet, E.; Herrero, A.; Grant, A.; Downey, J.; Barreiro, L. B.; Yipp, B. G.; Soehnlein, O.; Divangahi, M.
10.1101/2024.09.02.610822 — immunology — Posted on 2024-09-03
5075 CAR-T cells targeting CCR9 and CD1a for the treatment of T cell acute lymphoblastic leukemia
Tirado, N.; Mansilla, M. J.; Martinez-Moreno, A.; Alcain, J.; Garcia-Peydro, M.; Roca-Ho, H.; Fernandez-Fuentes, N.; Garcia-Perez, A.; Guerrero-Murillo, M.; Falgas, A.; Velasco-Hernandez, T.; Vinyoles, M.; Bueno, C.; Engel, P.; Gonzalez, E. A.; Vick, B.; Jeremias, I.; Caye-Eude, A.; Baruchel, A.; Cave, H.; Genesca, E.; Ribera, J.; Diaz-Beya, M.; Ramirez-Orellana, M.; Torrebadell, M.; Diaz, V. M.; Toribio, M. L.; Sanchez-Martinez, D.; Menendez, P.
10.1101/2024.09.02.610843 — immunology — Posted on 2024-09-03
5077 Disease-associated microglia and activation of CD8+ T cells precede neuronal cell loss in a model of hereditary spastic paraplegia
Frolov, A.; Huang, H.; Schütz, D.; Köhne, M.; Blank-Stein, N.; Osei-sarpong, C.; Büttner, M.; Elmzzahi, T.; Khundadze, M.; Becker, M.; Bonaguro, L.; Hübner, C. A.; Händler, K. A.; Stumm, R.; Mass, E.; Beyer, M.
10.1101/2024.09.02.610538 — immunology — Posted on 2024-09-03
5078 Generation of motor program diversity and variability through inhibitory circuit motifs in the Drosophila larval locomotor system
Francis, J.; Gibeily, C. R.; Smith, W. V.; Petropoulos, I. S.; Anderson, M.; Prinz, A. A.; Heitler, W. J.; Pulver, S. R.
10.1101/2024.09.02.610491 — neuroscience — Posted on 2024-09-03
5082 An aging-sensitive compensatory secretory phospholipase that confers neuroprotection and cognitive resilience
Vicidomini, C.; Goode, T. D.; McAvoy, K.; Yu, R.; Beveridge, C.; Iyer, S.; Victor, M. B.; Leary, N.; Evans, L.; Steinbaugh, M. J. B.; Lai, Z. W.; Lyon, M. C.; Silvestre, M. R. F. S.; Bonilla, G.; Sadreyev, R. I.; Walther, T. C.; Sui, S. H.; Saido, T.; Yamamoto, K.; Murakami, M.; Tsai, L.-H.; Chopra, G.; Sahay, A.
10.1101/2024.07.26.605338 — neuroscience — Posted on 2024-09-03
5083 Multisensory approach in Mental Imagery: ALE meta-analyses comparing Motor, Visual and Auditory Imagery
Van Caenegem, E. E.; Hardwick, R.; Waltzing, B.; Van Caenegem, G.; Moreno Verdu, M.; Mc Ateer, S.; Lennart, F.
10.1101/2024.09.02.610739 — neuroscience — Posted on 2024-09-03
5085 Refining Brain Stimulation Therapies: An Active Learning Approach to Personalization
Sendi, M. S.; Core, E.; Piallat, B.; Ellis, C. A.; Eggers, T. E.; Laxpati, N. G.; Mahmoudi, B.; Gutekunst, C.-A.; Devergnas, A. D.; Mayberg, H. S.; Gross, R. E.; Calhoun, V.
10.1101/2024.09.02.610880 — neuroscience — Posted on 2024-09-03
5086 Inferring Ligand-Receptor Interactions between GABAergic and Glutamatergic neurons during somatosensory cortex development
Mathieu, R.; Corbieres, L.; Draia-Nicolau, T.; Govindan, A.; Bensa, V.; Pallesi-Pocachard, E.; Silvagnoli, L.; Represa, A.; Cardoso, C.; Telley, L.; de Chevigny, A.
10.1101/2024.09.02.610245 — neuroscience — Posted on 2024-09-03
5089 FaPDA: Facial paralysis detection algorithm applied in mice
Perrusquia-Hernandez, E.; Villeda-Arias, D. I.; Montes-Angeles, C. D.; Andrade-Gonzalez, R. D.; Lomeli-Gonzalez, J.; Perez-Martinez, I. O.
10.1101/2024.09.02.610902 — neuroscience — Posted on 2024-09-03
5090 Neural population dynamics during sleep in a songbird vocal circuit resemble sharp wave ripple activity
Lorenz, C.; Das, A.; Centeno, E. G. Z.; Yeganegi, H.; Duvoisin, R.; Ursu, R.; Retailleau, A.; Giret, N.; Leblois, A.; Hahnloser, R. H. R.; Ondracek, J. M.
10.1101/2024.09.03.610933 — neuroscience — Posted on 2024-09-03
5091 Evolutionary conserved RLF, a plant cytochrome b5-like heme-binding protein, is essential for organ development in Marchantia polymorpha
Iwata, K. P.; Shimizu, T.; Sakai, Y.; Furuya, T.; Fukumura, H.; Kondo, Y.; Masuda, T.; Ishizaki, K.; Fukaki, H.
10.1101/2024.09.02.610766 — plant biology — Posted on 2024-09-03
5093 Subunit-specific conductance of single HCN pacemaker channels at femtosiemens resolution
Benndorf, K.; Enke, U.; Tewari, D.; Kusch, J.; Liu, H.; Sun, H.; Schmauder, R.; Sattler, C.
10.1101/2024.09.02.610748 — physiology — Posted on 2024-09-03
5094 Early brain neuroinflammatory and metabolic changes identified by dual tracer microPET imaging in mice with acute liver injury
Palandira, S.; Falvey, A.; Carrion, J.; Zeng, Q.; Chaudhry, S.; Grossman, K.; Turecki, L.; Nguyen, N.; Brines, M.; Chavan, S. S.; Metz, C. N.; Al-Abed, Y.; Chang, E. H.; Ma, Y.; Eidelberg, D.; Vo, A.; Tracey, K. J.; Pavlov, V. A.
10.1101/2024.09.02.610840 — physiology — Posted on 2024-09-03
5095 CD300e as a Driver of Immunosuppressive Tumor Microenvironment in Colorectal Cancer
Barizza, A.; Vassallo, S.; Masatti, L.; Lonardi, S.; Bugatti, M.; Coletta, S.; Giacometti, S.; Pizzini, S.; Vermi, W.; Munari, F.; Gnoato, N.; Fassan, M.; Nigro, G.; Spolverato, G.; Calura, E.; Codolo, G.
10.1101/2024.09.01.610700 — cancer biology — Posted on 2024-09-03
5096 PPARgamma, a key modulator of metabolic reprogramming, stemness and chemoresistance associated with retrodifferentiation in human hepatocellular carcinomas
Daniel, Y.; Rauch, C.; Moutaux, L.; Fekir, K.; Desquilles, L.; Cano, L.; Catheline, D.; Pierre, S.; Burel, A.; Savary, C.; Ribault, C.; Bendacid, C.; Clement, B.; Aninat, C.; Rioux, V.; Musso, O.; Fromenty, B.; Cabillic, F.; Corlu, A.
10.1101/2024.09.02.610533 — cancer biology — Posted on 2024-09-03
5098 Scattering-Based Super-Resolution Optical Fluctuation Imaging
Yudovich, S.; Posnjak, G.; Shani, L.; Teblum, E.; Liedl, T.; Enderlein, J.; Weiss, S.
10.1101/2024.09.02.610873 — biophysics — Posted on 2024-09-03
5099 eProbe: a capture probe design toolkit for genetic diversity reconstructions from ancient environmental DNA
Huang, Z.; Gu, Z.; Cai, Y.; Macleod, R.; Xue, Z.; Dong, H.; Overballe-Petersen, S.; Liu, S.; Gao, Y.; Li, H.; Tang, S.; Diao, X.; Joergensen, M. E.; Dockter, C.; Vinner, L.; Willerslev, E.; Chen, F.; Wang, H.; Wang, Y.
10.1101/2024.09.02.610737 — bioinformatics — Posted on 2024-09-03
5105 Rapid precision targeting of nanoparticles to lung via caveolae pumping system in endothelium
Nayak, T.; Chrastina, A.; Valencia, J.; Yedidsion, R.; Buss, T.; Cederstrom, B.; Koziol, J.; Levin, M. D.; Olenyuk, B.; Schnitzer, J. E.
10.1101/2024.09.01.610705 — bioengineering — Posted on 2024-09-03
5106 Design of an Artificial Natural Killer Cell Mimicking System to Target Tumour Cells
Chugh, V.; K., V. K.; Quandt, D.; Kelly, S.; King, D.; Jensen, L.; Simpson, J.
10.1101/2024.09.02.610779 — bioengineering — Posted on 2024-09-03
5107 Architecture of the ATP-driven motor for protein import into chloroplasts
wang, n.; Xing, J.; Su, X.; Pan, J.; Chen, H.; Shi, L.; Si, L.; Yang, W.; Li, M.
10.1101/2024.09.02.610899 — biochemistry — Posted on 2024-09-03
5108 A reliance on human habitats is key to the success of an introduced predatory reptile
Major, T.; Jeffrey, L.; Limia Russel, G.; Bracegirdle, R.; Gandini, A.; Morgan, R.; Marshall, B. M.; Mulley, J. F.; Wüster, W.
10.1101/2024.09.01.610713 — animal behavior and cognition — Posted on 2024-09-03
5114 Local Gene Duplications Drive Extensive NLR Copy Number Variation Across Multiple Genotypes of Theobroma cacao
Winters, N. P.; Wafula, E. K.; Timilsena, P. R.; Ralph, P. E.; Maximova, S. N.; dePamphilis, C. W.; Guiltinan, M. J.; Marden, J. H.
10.1101/2024.09.01.610724 — evolutionary biology — Posted on 2024-09-03
5115 Too hot to handle? The impact of the 2023 marine heatwave on Florida Keys coral
Neely, K. L.; Nowicki, R. J.; Dobler, M. A.; Chaparro, A. A.; Miller, S. M.; Toth, K. A.
10.1101/2024.08.31.610635 — ecology — Posted on 2024-09-03
5118 Standardizing marine habitat modelling practices to enhance inter-comparability across biological observations
Schickele, A.; Clerc, C.; Benedetti, F.; De Angelis, D.; Hofmann Elizondo, U.; Muennich, M.; Irisson, J.-O.; Vogt, M.
10.1101/2024.09.02.610745 — ecology — Posted on 2024-09-03
5121 Contractile forces direct the chiral swirling of minimal cell collectives
Badih, G.; Schaeffer, A.; Vianay, B.; Smilovici, P.; Blanchoin, L.; THERY, M.; Kurzawa, L.
10.1101/2024.09.02.610752 — cell biology — Posted on 2024-09-03
5122 A spatial atlas of human gastro-intestinal acute GVHD reveals epithelial and immune dynamics underlying disease pathophysiology
Azulay, N.; Milo, I.; Bussi, Y.; Ben Uri, R.; Keidar Haran, T.; Eldar, M.; Elhanani, O.; Harnik, Y.; Yakubovsky, O.; Nachmany, I.; Salame, T. M.; Wartenberg, M.; Bertheau, P.; Michonneau, D.; Socie, G.; Keren, L.
10.1101/2024.09.02.610085 — immunology — Posted on 2024-09-03
5124 Ongoing activation of visual cortex and superior colliculus in the rd10 mouse model of retinitis pigmentosa
Rueland, T.; Doerenkamp, K.; Graff, P. S.; Wetz, S.; Jain, A.; Nabbefeld, G.; Gehlen, J.; Gilissen, S.; Arckens, L.; Musall, S.; Mueller, F.; Kampa, B.
10.1101/2024.09.02.610761 — neuroscience — Posted on 2024-09-03
5126 Biases in volumetric versus surface analyses in population receptive field mapping
Linahrdt, D.; Woletz, M.; Paz-Alonso, P. M.; Windischberger, C.; Lerma-Usabiaga, G.
10.1101/2024.09.02.610800 — neuroscience — Posted on 2024-09-03
5128 Quantitative modelling of fate specification in the C. elegans postembryonicM lineage reveals a missing spatiotemporal signal
Planterose Jimenez, B.; Blackwell, A. R.; Ramalho, J. J.; van den Heuvel, S.; ten Tusscher, K.; Tsingos, E.
10.1101/2024.09.01.610667 — systems biology — Posted on 2024-09-03
5129 Interpretable scRNA-seq Analysis with Intelligent Gene Selection
Ni, T.; Zhang, X.; Jin, K.; Pei, G.; Xue, N.; Yan, G.; Li, T.; Li, B.
10.1101/2024.09.01.610665 — bioinformatics — Posted on 2024-09-03
5131 Extinction potential from invasive alien species
Philippe-Lesaffre, M.; Arbieu, U.; Bang, A.; Camacho, M.; Cuthbert, R.; Genovesi, P.; Kumschick, S.; Pili, A.; Seebens, H.; Wang, S.; Latombe, G.
10.1101/2024.09.01.610685 — ecology — Posted on 2024-09-03
5134 The speed limits for tau pathology progression in Alzheimer's disease
Hoenig, M.; Dzialas, V.; Doering, E.; Bischof, G.; van Eimeren, T.; Drzezga, A.
10.1101/2024.09.02.610787 — neuroscience — Posted on 2024-09-03
5135 Connectivity between supplementary motor complex and primary motor cortex: a dual-coil paired-pulse TMS study
Kim, H.; Lei, Y.; Bao, S.; Huynh, A. T.; Buchanan, J. J.; Bernard, J. A.; Brown, J. C.; Wright, D. L.
10.1101/2024.08.31.610643 — neuroscience — Posted on 2024-09-03
5136 Lower-Limb Muscle Synergies in Musician's Dystonia: A Case Study of a Drummer
Sata, S.; Honda, K.; Yamaguchi, S.; Komine, M.; Kim, S.; Kashino, M.; Hagio, S.; Fujii, S.
10.1101/2024.09.02.610624 — neuroscience — Posted on 2024-09-03
5141 Pain distribution can be determined by classical conditioning
Nastaj, J.; Skalski, J.; Nowak, D.; Kruszyna, N.; Babel, P.; Szikszay, T.; Luedtke, K.; Gnat, R.; Adamczyk, W. M.
10.1101/2024.08.31.609921 — physiology — Posted on 2024-09-03
5144 Freeze-dried porous collagen scaffolds for the repair of volumetric muscle loss injuries
Basurto, I. M.; Boudreau, R. D.; Bandara, G. C.; Muhammad, S. A.; Christ, G. J.; Caliari, S. R.
10.1101/2024.08.30.610194 — bioengineering — Posted on 2024-09-03
5148 Phosphorylation of CRYAB Induces a Condensatopathy to Worsen Post-Myocardial Infarction Left Ventricular Remodeling.
Islam, M.; Rawnsley, D. R.; Ma, X.; Navid, W.; Zhao, C.; Foroughi, L.; Murphy, J. T.; Navid, H.; Weinheimer, C. J.; Kovacs, A.; Nigro, J.; Diwan, A.; Chang, R.; Kumari, M.; Young, M.; Razani, B.; Margulies, K.; Abdellatif, M.; Sedej, S.; Javaheri, A.; Covey, D. F.; Mani, K.; Diwan, A.
10.1101/2024.08.30.610556 — cell biology — Posted on 2024-09-03
5150 A human neuronal model of sporadic Alzheimer's disease induced by FBXO2 downregulation shows A β aggregation, tau hyperphosphorylation and functional network impairment
Gonzalez-Diaz, A.; Possenti, A.; Urrutia, G. A.; Bian, Y.; Kedia, S.; Boeken, D.; Lim, C. M.; Licastro, D.; Mannini, B.; Klenerman, D.; Vendruscolo, M.
10.1101/2024.09.01.610673 — neuroscience — Posted on 2024-09-03
5151 Unsupervised learning for labeling global glomerulosclerosis
Weishaupt, H.; Besusparis, J.; Weis, C.-A.; Porubsky, S.; Laurinavicius, A.; Leh, S.
10.1101/2024.09.01.610244 — pathology — Posted on 2024-09-03
5152 Targeting DLK1 improves survival in patient-derived xenograft models of myeloid leukemia associated with Down syndrome
Barwe, S. P.; Tavenner, M.; van Berkel, P.; Sebastian, A.; Ries, R. E.; Meshinchi, S.; Hitzler, J.; Pikman, Y.; Kolb, E. A.; Gopalakrishnapillai, A.
10.1101/2024.08.30.608947 — cancer biology — Posted on 2024-09-03
5154 SMARTER-database: a tool to explore genomic diversity in small ruminants
Cozzi, P.; Manunza, A.; Ramirez-Diaz, J.; Tsartsianidou, V.; Gkagkavouzis, K.; Peraza, P.; Johansson, A. M.; Arranz, J. J.; Freire, F.; Kusza, S.; Biscarini, F.; Peters, L.; Tosser-Klopp, G.; Ciappesoni, G.; Triantafyllidis, A.; Rupp, R.; Servin, B.; Stella, A.
10.1101/2024.09.01.610681 — bioinformatics — Posted on 2024-09-03
5158 Organoid Modeling and Single-Cell Profiling Uncover the Migration Mechanism of Smooth Muscle Cells in Moyamoya Disease
He, S.; Zhang, J.; Wang, X.; Qi, Z.; Zhou, Z.; Wang, Y.; Xu, S.; Li, D.; Ye, X.; Liu, Z.; Hao, X.; Zhao, Y.; Wang, R.
10.1101/2024.09.01.610617 — cell biology — Posted on 2024-09-03
5161 Cestode larvae excite host neuronal circuits via glutamatergic signaling.
de Lange, A.; Tomes, H.; Selfe, J. S.; Prodjinotho, U. F.; Verhoog, M. B.; Mahanty, S.; Smith, K.; Horsnell, W.; Sikasunge, C.; da Costa, C. P.; Raimondo, J. V.
10.1101/859009 — neuroscience — Posted on 2024-09-03
5166 Extensive transmission and variation in a functional receptor for praziquantel resistance in endemic Schistosoma mansoni
Berger, D. J.; Park, S.-K.; Crellen, T.; Vianney, T. J.; Kabatereine, N. B.; Cotton, J. A.; Sanya, R.; Elliot, A.; Tukahebwa, E. M.; Adriko, M.; Standley, C. J.; Gouvras, A.; Kinunghi, S.; Haas, H.; Rabone, M.; Emery, A.; Lamberton, P. H. L.; Webster, B. L.; Allan, F.; Buddenborg, S.; Berriman, M.; Marchant, J. S.; Doyle, S. R.; Webster, J. P.
10.1101/2024.08.29.610291 — genomics — Posted on 2024-09-03
5167 A genomic duplication spanning multiple P450s contributes to insecticide resistance in the dengue mosquito Aedes aegypti
Bacot, T.; Haberkorn, C.; Guilliet, J.; Cattel, J.; Kefi, M.; Nadalin, L.; Filee, J.; Boyer, F.; Gaude, T.; Laporte, F.; Tutagata, J.; Vontas, J.; Dusfour, I.; Bonneville, J.-M.; David, J.-P.
10.1101/2024.04.03.587871 — evolutionary biology — Posted on 2024-09-03
5168 Mast cells are not essential for pubertal mammary gland branching.
Kapoor, S.; Marsden, J.; Munz, C. M.; Carvalho, C.; Magalhaes Pinto, M.; Malengier-Devlies, B.; Becker, S.; Seuzaret, G.; Patatsos, K.; Akyol, R.; DALOD, M.; Pedersen, A. B.; Wilson, G. J.; Gentek, R.
10.1101/2024.08.30.610382 — developmental biology — Posted on 2024-09-03
5170 Genetic diversity and evolution of rice centromeres
Xie, L.; Huang, Y.; Huang, W.; Shang, l.; Sun, Y.; Chen, Q.; Bi, S.; Suo, M.; Zhang, S.; Yang, C.; Zheng, X.; Jin, W.; Qian, Q.; Fan, L.; Dongya, W.
10.1101/2024.07.28.605524 — genetics — Posted on 2024-09-03
5171 Loss of TLR9 expression in breast cancer tumour cells and its role in the cell cycle.
Sible, E.; Weitsman, G.; Amouya, S.; Roblot, G.; Marotel, M.; Pescarmona, R.; Bendriss-Vermare, N.; Gillet, C.; Ceesay, A.; Michallet, M.-C.; Caux, C.; Cosset, F.-L.; Al-alem, U.; Ng, T.; Hasan, U. A.
10.1101/2024.07.04.601915 — cell biology — Posted on 2024-09-03
5173 Emergence and spread of feline infectious peritonitis due to a highly pathogenic canine/feline recombinant coronavirus
Atippa, C.; Warr, A. S.; Epaminondas, D.; O'Shea, M.; Hanton, A. J.; Fletcher, S. L.; Malbon, A.; Lyraki, M.; Hammond, R.; Hardas, A.; Zanti, A.; Loukaidou, S.; Gentil, M.; Gunn-Moore, D.; Mazeri, S.; Tait-Burkard, C.
10.1101/2023.11.08.566182 — microbiology — Posted on 2024-09-03
5176 Dietary zinc restriction mimics protein restriction and extends lifespan in Drosophila
Kosakamoto, H.; Aikawa, H.; Kitazawa, S.; Sakuma, C.; Okada, R.; Miura, M.; Obata, F.
10.1101/2024.08.28.610190 — physiology — Posted on 2024-09-03
5177 Cytosolic S100A8/A9 promotes Ca2+ supply at LFA-1 adhesion clusters during neutrophil recruitment
Napoli, M.; Immler, R.; Rohwedder, I.; Lupperger, V.; Pfabe, J.; Gonzalez Pisfil, M.; Yevtushenko, A.; Vogl, T.; Roth, J.; Salvermoser, M.; Dietzel, S.; Slak Rupnik, M.; Marr, C.; Walzog, B.; Sperandio, M.; Pruenster, M.
10.1101/2024.04.16.589738 — physiology — Posted on 2024-09-03
5180 Hippocampal neuroinflammation causes sex-specific disruptions in action selection, food approach memories, and neuronal activation
Ganesan, K.; Ghorbanpour, S.; Kendall, W.; Broome, S. T.; Gladding, J. M.; Dhungana, A.; Abiero, A. R.; Mahmoudi, M.; Castorina, A.; Kendig, M. D.; Becchi, S.; Valova, V.; Cole, L.; Bradfield, L. A.
10.1101/2024.05.19.594460 — animal behavior and cognition — Posted on 2024-09-03
5182 Novel derivatives of BCV and (S)-HPMPA inhibit orthopoxviruses and human adenoviruses more potently than BCV
Zhang, Y.; Wan, Y.; Guo, C.; Zhu, Z.; Qiu, C.; Lu, J.; Zhou, Y.; Zheng, J.; Dai, F.; Cheng, X.; Deng, K.; Wang, W.; Wang, Y.; Zhang, W.
10.1101/2024.08.30.610570 — microbiology — Posted on 2024-09-03
5183 Unique growth and morphology properties of Clade 5 Clostridioides difficile strains revealed by single-cell time-lapse microscopy
Ribis, J. W.; Nieto-Acuna, C. A.; DiBenedetto, N.; Mehra, A.; Dong, Q.; Nagawa, I. L.; El Meouche, I.; Aldridge, B. B.; Dunlop, M. J.; Tamayo, R.; Singh, A.; Shen, A.
10.1101/2024.02.13.580212 — microbiology — Posted on 2024-09-03
5187 Ultrack: pushing the limits of cell tracking across biological scales
Bragantini, J.; Theodoro, I.; Zhao, X.; Huijben, T. A. P. M.; Hirata-Miyasaki, E.; VijayKumar, S.; Balasubramanian, A.; Lao, T.; Agrawal, R.; Xiao, S.; Lammerding, J.; Mehta, S.; Falcao, A.; Jacobo, A.; Lange, M.; Royer, L. A.
10.1101/2024.09.02.610652 — developmental biology — Posted on 2024-09-03
5188 The contributions of biological maturity and experience to fine motor development in adolescence
Berencsi, A.; Gombos, F.; Feher, L. J.; Gervan, P.; Utczas, K.; Olah, G.; Troznai, Z.; Kovacs, I.
10.1101/2024.09.02.610814 — neuroscience — Posted on 2024-09-03
5189 Inferring Ligand-Receptor Interactions between GABAergic and Glutamatergic neurons during somatosensory cortex development
Mathieu, R.; Corbieres, L.; Draia-Nicolau, T.; Govindan, A.; Bensa, V.; Pallesi-Pocachard, E.; Represa, A.; Cardoso, C.; Telley, L.; de Chevigny, A.
10.1101/2024.09.02.610245 — neuroscience — Posted on 2024-09-03
5190 Are you talking to me? How the choice of speech register impacts listeners' hierarchical encoding of speech.
Piazza, G.; Carta, S.; Ip, E.; Perez-Navarro, J.; Kalashnikova, M.; Martin, C. D.; Di Liberto, G. M.
10.1101/2024.09.02.610805 — neuroscience — Posted on 2024-09-03
5195 Pangenomics to understand prophage dynamics in the Pectobacterium genus and the radiating lineages of P. brasiliense
Pardeshi, L. A.; van Duivenbode, I.; Pel, M. J. C.; Jonkheer, E. M.; Kupczok, A.; de Ridder, D.; Smit, S.; van der Lee, T.
10.1101/2024.09.02.610764 — bioinformatics — Posted on 2024-09-02
5198 The Enhanced Activation of Innate Immunity in Drosophila S2 Cells by Micrococcus luteus is Mediated by Relish
Kachaev, Z. M.; Ghassah, M.; Musabirov, A. A.; Shaposhnikov, A. V.; IToropygin, I. Y.; Polunina, Y. A.; Stepanov, N. G.; Chmykhalo, V. K.; Shidlovskii, Y.
10.1101/2024.09.02.610512 — molecular biology — Posted on 2024-09-02
5199 Molecular insights into dynamic protein structures by high-contrast crosslinking mass spectrometry
Chen, Z. A.; Absmeier, E.; Stowell, J.; Sinn, L. R.; Shakeel, S.; Sijacki, T.; Njo, K.; Stahl, K.; Rullmann, E.; O'Reilly, F. J.; Passmore, L. A.; Rappsilber, J.
10.1101/2024.09.02.610668 — molecular biology — Posted on 2024-09-02
5200 Circular RNAs correlate with DNA damage in ageing human placental tissue and in stillbirth
Arthurs, A. L.; Jackson, M. R.; McCullough, D.; SCOTT, H.; Barnett, C. P.; Webb, S. T.; Smith, M. D.; Jankovic-Karasoulos, T.; Dekker, G. A.; Roberts, C. T.
10.1101/2024.09.02.610398 — molecular biology — Posted on 2024-09-02
5203 Di-HAMP domains of a cytoplasmic chemoreceptor modulate nucleoid array formation and downstream signalling
Jazleena, P. J.; Das, A.; Guiseppi, A.; Debard, F.; Sharma, J.; Yaikhomba, M.; Mignot, T.; Mauriello, E. M.; Gayathri, P.
10.1101/2024.09.02.610768 — microbiology — Posted on 2024-09-02
5204 Early Fibrin Biofilm Development in Cardiovascular Infections
Oukrich, S.; Hong, J.; Leon-Grooters, M.; van Cappellen, W.; Slotman, J. A.; Koenderink, G. H.; van Wamel, W. J. B.; de Maat, M. P. M.; Kooiman, K.; Lattwein, K. R.
10.1101/2024.09.02.610803 — microbiology — Posted on 2024-09-02
5205 Phosphatase-independent suppression of mucosal inflammation and disease progression by Salmonella SopB
Diab, N.; Stange, E. L.; Yong, C. H.; Deiwick, J.; Vucur, M.; Luedde, T.; Hensel, M.; Torow, N.; Zhang, K.; Hornef, M. W.
10.1101/2024.09.02.610793 — microbiology — Posted on 2024-09-02
5206 Yeast-MetaTwin for Systematically Exploring Yeast Metabolism through Retrobiosynthesis and Deep Learning
Wu, K.; Liu, H.; Sun, M.; Mao, R.; Jiang, Y.; Kerkhoven, E. J.; Nielsen, J.; Chen, Y.; Li, F.
10.1101/2024.09.02.610684 — synthetic biology — Posted on 2024-09-02
5207 Phage-mediated intercellular CRISPRi for biocomputation in bacterial consortia
Pujar, A.; Pathania, A.; Hopper, C.; Pandi, A.; Fugger, M.; Nowak, T.; Kushwaha, M.
10.1101/2024.09.02.610857 — synthetic biology — Posted on 2024-09-02
5209 Multi-modal, Label-free, Optical Mapping of Cellular Metabolic Function and Oxidative Stress in 3D Engineered Brain Tissue Models
Zhang, Y.; Savvidou, M.; Liaudanskaya, V.; Ramanathan, V.; Bui, T.; Matthew, L.; Sze, A.; Ugwu, U. O.; Yuhang, F.; Matthew, D. E.; Chen, X.; Nasritdinova, S.; Dey, A.; Miller, E. L.; Kaplan, D. L.; Georgakoudi, I.
10.1101/2024.08.08.607216 — bioengineering — Posted on 2024-09-02
5210 Sex-dependent metabolic remodeling of kidneys revealed by arteriovenous metabolomics
Kelly, M. E.; Hoffner, L. A.; Ramirez, C. B.; Anica, A. L.; Kim, J.; Tong, G.; Kim, Y.; Choi, W.; Jang, K.; Alam, Y. H.; Jung, S.; Le, J.; Tamburini, I.; Lopez, M. L.; Bae, H.; Chun, Y.; Song, W.-S.; Martinez, T. F.; Jang, C.; Lee, G.
10.1101/2024.09.02.610869 — biochemistry — Posted on 2024-09-02
5211 Methods for high throughput discovery of fluoroprobes that recognize tau fibril polymorphs
Carroll, E. C.; Yang, H. E.; Jones, J. G.; Oehler, A.; Charvat, A. F.; Montgomery, K. M.; Yung, A.; Millbern, Z.; Vinueza, N. R.; Degrado, W. F.; Mordes, D. A.; Condello, C.; Gestwicki, J. E.
10.1101/2024.09.02.610853 — biochemistry — Posted on 2024-09-02
5212 Design of linked-domain protein inhibitors of UBE2D as tools to study cellular ubiquitination
Bukhari, Z.; Gu, L.; Nederstigt, A. E.; Cope, L. J.; Bolhuis, D. L.; Harvey, K.; Allen, T.; Hill, S.; Yang, Y.; Lawson, G.; Lu, C.; Tran, T.; Leah, P.; Low, L.; Chiang, A.; Song, J.; Fong, M. V.; Rangel, V. M.; Chan, W. K.; Kleiger, G.; Goldfarb, D.; Vierra, C. A.; Brown, N. G.; Harrison, J. S.
10.1101/2024.09.02.610852 — biochemistry — Posted on 2024-09-02
5214 Convergent evolution of somatic escape variants in SERPINA1 in the liver in alpha-1 anti-trypsin deficiency
Brzozowska, N.; Wu, L. Y. D.; Khodzhaeva, V.; Griffiths, W. J.; Duckworth, A.; Jung, H.; Coorens, T. H. H.; Hooks, Y.; Chambers, J. E.; Campbell, P. J.; Marciniak, S. J.; Hoare, M.
10.1101/2024.09.02.610686 — genomics — Posted on 2024-09-02
5218 DNA flexibility regulates transcription factor binding to nucleosomes
Mariani, L.; Liu, X.; Lee, K.; Gisselbrecht, S. S.; Cole, P. A.; Bulyk, M. L.
10.1101/2024.09.02.610559 — molecular biology — Posted on 2024-09-02
5220 Novel derivatives of BCV and (S)-HPMPA inhibit orthopoxviruses and human adenoviruses more potently than BCV
Zhang, Y.; Wan, Y.; Guo, C.; Zhu, Z.; Qiu, C.; Lv, J.; Zhou, Y.; Zheng, J.; Dai, F.; Cheng, X.; Deng, K.; Wang, W.; Wang, Y.; Zhang, W.
10.1101/2024.08.30.610570 — microbiology — Posted on 2024-09-02
5222 Yersinia pseudotuberculosis growth arrest during type-III secretion system expression is associated with altered ribosomal protein expression and decreased gentamicin susceptibility
Greene, J.; Snyder, R. A.; Cotten, K. L.; Huiszoon, R.; Chu, S.; Braza, R. E. D.; Chapin, A. A.; Stine, J. M.; Bentley, W. E.; Ghodssi, R.; Davis, K. M.
10.1101/2024.09.02.610769 — microbiology — Posted on 2024-09-02
5225 Nucleocytoviricota viral factories are transient organelles made by phase separation
Rigou, S.; Schmitt, A.; Lartigue, A.; Danner, L.; Giry, C.; Trabelsi, F.; Belmudes, L.; Olivero-Deibe, N.; Coute, Y.; Berois, M.; Legendre, M.; Jeudy, S.; Abergel, C.; Bisio, H.
10.1101/2024.09.01.610734 — microbiology — Posted on 2024-09-02
5231 Human DCP1 is crucial for mRNA decapping and possesses paralog-specific gene regulating functions
Chen, T.-W.; Liao, H.-W.; Noble, M.; Siao, J.-Y.; Cheng, Y.-H.; Chiang, W.-C.; Lo, Y.-T.; Chang, C.-T.
10.1101/2023.09.04.556219 — molecular biology — Posted on 2024-09-02
5233 Brain structure and activity predicting cognitive maturation in adolescence
Zhu, J.; Garin, C. M.; Qi, X.-L.; Machado, A.; Wang, Z.; Ben Hamed, S.; Stanford, T. R.; Salinas, E.; Whitlow, C. T.; Anderson, A. W.; Zhou, X. M.; Calabro, F. J.; Luna, B.; Constantinidis, C.
10.1101/2024.08.23.608315 — neuroscience — Posted on 2024-09-02
5237 Metformin acts directly in the brain to slow features of neurodegeneration.
Harding, E. C.; Chen, H.-J. C.; Shepilov, D.; Welzer, M.; Macarelli, V.; Schwiening, A.; Rowley, C.; Aggarwal, S.; Swinden, D.; Kronenberg-versteeg, D.; Merkle, F. T.
10.1101/2023.07.18.549549 — neuroscience — Posted on 2024-09-02
5238 Brain white matter pathways of resilience to chronic back pain: a multisite validation
Misic, M.; Lee, N.; Zidda, F.; Sohn, K.; Usai, K.; Löffler, M.; Uddin, N.; Farooqi, A.; Schifitto, G.; Zhang, Z.; Nees, F.; Geha, P.; Flor, H.
10.1101/2024.01.30.578024 — neuroscience — Posted on 2024-09-02
5239 AMOEBA Polarizable Molecular Dynamics Simulations of Guanine Quadruplexes: from the c-Kit Proto-oncogene to HIV-1
El Ahdab, D. S.; Lagardere, L.; Hobaika, Z.; Jaffrelot Inizan, T.; Celerse, F.; Gresh, N.; Maroun, R. G.; Piquemal, J.-P.
10.1101/2024.08.28.610081 — biophysics — Posted on 2024-09-02
5241 De novo design of Ras isoform selective binders
Zhang, J. Z.; Li, X.; Liu, C.; Jiang, H.; Wu, K.; Baker, D.
10.1101/2024.08.29.610300 — bioengineering — Posted on 2024-09-02
5242 Experimental evolution of gene essentiality in bacteria
Bao, L.; Zhu, Z.; Ismail, A.; Zhu, B.; Anandan, V.; Whiteley, M.; Kitten, T.; Xu, P.
10.1101/2024.07.16.600122 — evolutionary biology — Posted on 2024-09-02
5244 T-follicular helper cells are epigenetically poised to transdifferentiate into T-regulatory type-1 cells
Garnica, J.; Sole, P.; Yamanouchi, J.; Moro, J.; Mondal, D.; Fandos, C.; Serra, P.; Santamaria, P.
10.1101/2024.05.17.594762 — immunology — Posted on 2024-09-02
5247 Pangenomic context reveals the extent of intraspecific plant NLR evolution
Teasdale, L. C.; Murray, K. D.; Collenberg, M.; Contreras-Garrido, A.; Schlegel, T.; van Ess, L.; Jüttner, J.; Lanz, C.; Deusch, O.; Fitz, J.; Mencia, R.; Velthoven, R. v. D.; Drost, H.-G.; Weigel, D.; Shirsekar, G.
10.1101/2024.09.02.610789 — plant biology — Posted on 2024-09-02
5248 Soil nutrition-dependent dynamics of the root-associated microbiome in paddy rice
Adachi, A.; Utami, Y. D.; Dominguez, J. J. A.; Fuji, M.; Kirita, S.; Imai, S.; Murakami, T.; Hongoh, Y.; Shinjo, R.; Kamiya, T.; Fujiwara, T.; Minamisawa, K.; Ono, N.; Kanaya, S.; Saijo, Y.
10.1101/2024.09.02.610732 — plant biology — Posted on 2024-09-02
5249 Raffinose induces autophagy to promote plant growth
Magen, S.; Daniel, S.; Weiss, S.; Factor, D. J.; Mursalimov, S.; Soroka, Y.; Michaeli, S.; Avin-Wittenberg, T.
10.1101/2024.09.02.610801 — plant biology — Posted on 2024-09-02
5250 Transposable elements are entangled in rapid adaptation to climate change
Potapenko, E. V.; Schwartz, D.; Mandel, T.; Ashkenazy, N.; Fuerst, D.; Atzmon, G.; Korol, A. B.; Kantar, M. B.; Bar-Massada, A.; Hubner, S.
10.1101/2024.09.02.610836 — plant biology — Posted on 2024-09-02
5251 KAI2-dependent signaling controls vegetative reproduction in Marchantia polymorpha through activation of LOG-mediated cytokinin synthesis
Komatsu, A.; Fujibayashi, M.; Kumagai, K.; Suzuki, H.; Hata, Y.; Takebayashi, Y.; Kojima, M.; Sakakibara, H.; Kyozuka, J.
10.1101/2024.09.02.610783 — plant biology — Posted on 2024-09-02
5253 Oversized cells activate global proteasome-mediated protein degradation to maintain cell size homeostasis
Liu, S.; Tan, C.; Melo-Gavin, C.; Ginzberg, M. B.; Blutrich, R.; Patel, N.; Rape, M.; Mark, K. G.; Kafri, R.
10.1101/2021.11.09.467936 — cell biology — Posted on 2024-09-02
5254 Ethanol reduces grapevine water consumption by limiting transpiration
Ait Kaci, N.; Diot, A.; Quinquiry, B.; Yobregat, O.; Pellegrino, A.; Maury, P.; Chervin, C.
10.1101/2024.08.31.610611 — plant biology — Posted on 2024-09-02
5256 Immune targets for schistosomiasis control identified by a genome-wide association study of East African snail vectors
Pennance, T.; Tennessen, J. A.; Spaan, J. M.; McQuistan, T.; Ogara, G.; Rawago, F.; Andiego, K.; Mulonga, B.; Odhiambo, M.; Mutuku, M. W.; Mkoji, G. M.; Loker, E. S.; Odiere, M. R.; Steinauer, M. L.
10.1101/2024.08.30.610565 — genomics — Posted on 2024-09-02
5259 Diel and seasonal rhythmicity in activity and corticosterone in an Arctic migratory herbivore: A multifaceted approach
de Jong, M. E.; Slettenhaar, A. J.; Fokkema, R. W.; Leh, M.; Barnreiter, E.; Griffin, L. R.; Loonen, M. J. J. E.; Millesi, E.; Moe, B.; Scheiber, I. B. R.
10.1101/2024.08.30.610510 — ecology — Posted on 2024-09-02
5262 Selective killing of plasma cell clones using splice-switching oligonucleotides targeting immunoglobulin variable exons.
Lambert, J.-M.; Praite, A.; Contini, M.; Ashi, M. O.; Marchalot, A.; Le Pennec, S.; Sirac, C.; Al Hayek, S.; Delpy, L.
10.1101/2024.08.30.610519 — immunology — Posted on 2024-09-02
5264 Deciphering regulation of FOXP3 expression in human conventional T cells
Umhoefer, J. M.; Arce, M. M.; Dajani, R.; Belk, J. A.; Mowery, C. T.; Nguyen, V.; Gowen, B. G.; Simeonov, D. R.; Curie, G. L.; Corn, J. E.; Chang, H. Y.; Marson, A.
10.1101/2024.08.30.610436 — immunology — Posted on 2024-09-02
5265 The over-activated peritoneal immune environment in endometriosis is characterised by a lack of PD-1 inhibition.
Tresso, A.; Thota, N.; James, C.; Borash, N.; Brennan, E.; Bayat, S.; Vollenhoven, B.; Tapmeier, T. T.
10.1101/2024.08.30.610573 — immunology — Posted on 2024-09-02
5267 Developmental and physiological impacts of pathogenic human huntingtin protein in the nervous system
Hana, T. A.; Mousa, V. G.; Lin, A.; Haj-Hussein, R. N.; Michael, A. H.; Aziz, M. N.; Kamaridinova, S. U.; Basnet, S.; Ormerod, K. G.
10.1101/2024.08.30.610525 — neuroscience — Posted on 2024-09-02
5268 Consumption of human-relevant levels of sucrose-water rewires macronutrient uptake and utilization mechanisms in a tissue specific manner
Ganguly, S.; Chattopadhyay, T.; Kazi, R.; Das, S.; Malik, B.; ML, U.; Iyer, P. S.; Kashiv, M.; Singh, A.; Ghadge, A.; Nair, S.; Sonawane, M.; Kolthur-Seetharam, U.
10.1101/2024.08.31.610015 — physiology — Posted on 2024-09-02
5269 Ketone Body Metabolism is Not Required for Improvement of Heart Failure by Ketogenic Diet in Mice
Foulks, Z.; Weinheimer, C. J.; Kovacs, A.; Michael, J.; Pyles, K. D.; Menezes, T. N.; Cho, K.; Patti, G. J.; McCommis, K. S.
10.1101/2024.08.30.610511 — physiology — Posted on 2024-09-02
5273 Distinct phenotypic consequences of cholangiocarcinoma-associated FGFR2 alterations depend on biliary epithelial maturity
O'Loughlin, E.; Zhang, Y.; Chiasson-MacKenzie, C.; Dave, P.; Rheinbay, E.; Stott, S. L.; McClatchey, A. I.
10.1101/2024.08.30.610360 — cancer biology — Posted on 2024-09-02
5278 Vascular network-inspired diffusible scaffolds for engineering functional neural organoids
Cai, H.; Tian, C.; Chen, L.; McCracken, K.; Tchieu, J.; Gu, M.; Mackie, K.; Guo, F.
10.1101/2024.08.31.610649 — bioengineering — Posted on 2024-09-02
5283 A scalable approach for genome-wide inference of ancestral recombination graphs
Gunnarsson, A. F.; Zhu, J.; Zhang, B. C.; Tsangalidou, Z.; Allmont, A.; Palamara, P. F.
10.1101/2024.08.31.610248 — genetics — Posted on 2024-09-02
5285 Species limits and hybridization in Andean leaf-eared mice (Phyllotis)
Quiroga-Carmona, M.; Liphardt, S.; Bautista, N. M.; Jayat, P.; Teta, P.; Malaney, J. L.; McFarland, T.; Cook, J. A.; Blumer, M.; Herrera, N. D.; Cheviron, Z. A.; Good, J.; D'Elia, G.; Storz, J.
10.1101/2024.08.31.610610 — evolutionary biology — Posted on 2024-09-02
5286 Quantifying Feral Pig Interactions to Inform Disease Transmission Networks
Proboste, T.; Turnlund, A.; Bengsen, A.; Gentle, M.; Wilson, C.; Harriott, L.; Fuller, R.; Marshall, D.; Soares-Magalhaes, R.
10.1101/2024.08.31.610621 — ecology — Posted on 2024-09-02
5288 Full-season spring migration counts reveal seasonal contrasts in raptor migration through the eastern Black Sea flyway
Tal, T.; Jansen, D.; Jansen, E.; Green, A. W.; Hoekstra, E.; Heetkamp, M.; T'jollyn, F.; Engelen, D.; Hoekstra, B.; Kaasiku, T.; Vansteelant, W. M. G.
10.1101/2024.08.30.610513 — ecology — Posted on 2024-09-02
5290 Selective disruption of Traf1/cIAP2 interaction attenuates inflammatory responses and limits sepsis and rheumatoid arthritis
Tang, Y.; aleithan, F.; Madahar, S. S.; Mirzaesmaeili, A.; Saran, S.; Tang, J.; Zangiabadi, S.; Inman, R.; Sweeney, G.; Abdul-Sater, A. A.
10.1101/2024.08.31.610651 — immunology — Posted on 2024-09-02
5291 Use of equine H3N8 hemagglutinin as a broadly protective influenza vaccine immunogen
Verhoeven, D.; Sponseller, B.; Crowe, J. E.; Bangaru, S.; Webby, R. J.; Lee, B. M.
10.1101/2024.08.30.610504 — immunology — Posted on 2024-09-02
5293 Evolution of lateralized gustation in nematodes
Mackie, M.; Le, V. V.; Carstensen, H. R.; Kushnir, N. R.; Castro, D. L.; Dimov, I. M.; Quach, K. T.; Cook, S. J.; Hobert, O.; Chalasani, S. H.; Hong, R. L.
10.1101/2024.08.31.610597 — neuroscience — Posted on 2024-09-02
5294 Discerning Specific Thrombolytic Activities and Blood Clot Degradomes of Diverse Snake Venoms with Untargeted Peptidomics
Smith, C. F.; Alpha Balde, M.; Bahrabadi, L.; Amponsah-Asamoah, M.; Larson, K. Y.; Maroney, S. P.; Ceja-Galindo, D.; Millimouno, M.; Camara, N.; Benjamin, J.; Brandehoff, N. P.; Modahl, C. M.; McCabe, M. C.; Cohen, M. J.; Castoe, T. A.; Balde, C.; Jackson, K.; Mackessy, S. P.; Hansen, K. C.; Saviola, A. J.
10.1101/2024.08.30.610527 — pharmacology and toxicology — Posted on 2024-09-02
5300 Insights into Treponema pallidum genomics from modern and ancient genomes using a novel mapping strategy
Pla-Diaz, M.; Akguel, G.; Molak, M.; du Plessis, L.; Panagiotopoulou, H.; Doan, K.; Bogdanowicz, W.; Dabrowski, P.; Oziemblowski, M.; Kwiatkowska, B.; Szczurowski, J.; Grzelak, J.; Arora, N.; Majander, K.; Gonzalez-Candelas, F.; Schuenemann, V.
10.1101/2023.02.08.526988 — microbiology — Posted on 2024-09-02
5301 Embryo-derived brain-resident macrophages sustain sleep-wake circuits
Seifinejad, A.; Bandarabadi, M.; Haddar, M.; Wundt, S.; Wingert, V.; Vassalli, A.; Hannibal, L.; Tafti, M.; Monaco, G.
10.1101/2024.01.22.576653 — neuroscience — Posted on 2024-09-02
5306 Nitrogen nutrition impacts grapevine esca leaf symptom incidence, physiology and metabolism.
Dell'Acqua, N.; Gambetta, G. A.; Comont, G.; Ferrer, N.; Rochepeau, A.; Petriacq, P.; Delmas, C. E. L.
10.1101/2024.08.31.610625 — plant biology — Posted on 2024-09-02
5311 Derivation of aerial insect concentration with a 94 GHz FMCW cloud radar
Lochmann, M.; Kalesse-Los, H.; Haest, B.; Vogl, T.; van Klink, R.; Addison, F.; Maahn, M.; Schimmel, W.; Wirth, C.; Quaas, J.
10.1101/2024.07.30.605781 — ecology — Posted on 2024-09-02
5313 Exchange, promiscuity, and orthogonality in de novo designed coiled-coil peptide assemblies
Kurgan, K. W.; Martin, F. J. O.; Dawson, W. M.; Brunnock, T.; Orr-Ewing, A. J.; Woolfson, D. N.
10.1101/2024.09.01.610678 — systems biology — Posted on 2024-09-02
5316 The Fusarium graminearum effector protease FgTPP1 suppresses immune responses and facilitates Fusarium Head Blight Disease
Darino, M.; Jaiswal, N.; Darma, R.; Kroll, E.; Urban, M.; Xiang, Y.; Kim, H.-S.; Myers, A.; Scofield, S.; Innes, R. W.; Hammond-Kosack, K. E.; Helm, M.
10.1101/2024.08.30.610543 — plant biology — Posted on 2024-09-02
5317 Responses of grapevine cells to physiological doses of ethanol, among which induced resistance to heat stress
Diot, A.; Madignier, G.; Maza, E.; Djari, A.; Di Valentin, O.; Chen, Y.; Blanchet, S.; Chervin, C.
10.1101/2024.08.31.610606 — plant biology — Posted on 2024-09-02
5318 The interaction between abiotic and biotic soil factors drive heterosis expression in maize
Clouse, K. M.; Ellis, M. L.; Ford, N. E.; Hostetler, R. L.; Balint-Kurti, P.; Kleiner, M.; Wagner, M. R.
10.1101/2024.08.30.610574 — plant biology — Posted on 2024-09-02
5323 Application of cryo-FIB-SEM for investigating organelle ultrastructure in guard cells of higher plants
Franzisky, B. L.; Zhang, X.; Burkhardt, C. J.; Majorovits, E.; Hummel, E.; Schertel, A.; Geilfus, C.-M.; Zoerb, C.
10.1101/2024.08.30.610476 — plant biology — Posted on 2024-09-02
5325 Efficient and sustained optogenetic control of sensory and cardiac systems
Alekseev, A.; Hunniford, V.; Zerche, M.; Jeschke, M.; El May, F.; Vavakou, A.; Siegenthaler, D.; Hueser, M. A.; Kiehn, S. M.; Garrido-Charles, A.; Meyer, A.; Rambousky, A.; Alvanos, T.; Witzke, I.; Rojas-Garcia, K. D.; Draband, M.; Cyganek, L.; Klein, E.; Ruther, P.; Huet, A.; Trenholm, S.; Mace, E.; Kusch, K.; Bruegmann, T.; Wolf, B. J.; Mager, T.; Moser, T.
10.1101/2023.11.17.567544 — biophysics — Posted on 2024-09-02
5327 Five-leaf generalizations of the D-statistic revealthe directionality of admixture
Leppälä, K.; da Silva Coelho, F. A.; Richter, M.; Albert, V. A.; Lindqvist, C.
10.1101/2024.02.24.581856 — genetics — Posted on 2024-09-02
5330 Gaze biases can reflect task-specific spatial memorization strategies
Chota, S.; Arora, K.; Kenemans, L.; Gayet, S.; Van der Stigchel, S.
10.1101/2024.08.30.610231 — neuroscience — Posted on 2024-09-02
5331 An automated microfluidic platform for toxicity testing based on Caenorhabditis elegans
Wu, J.; Xi, J.; Zhu, Z.; Peng, Q.; Liu, C.; Cao, Y.; Wan, Z.; Chen, X.; Luan, Y.
10.1101/2024.08.27.610021 — bioengineering — Posted on 2024-09-02
5332 Sequence-specific targeting of intrinsically disordered protein regions
Wu, K.; Jiang, H.; Hicks, D. R.; Liu, C.; Muratspahic, E.; Ramelot, T. A.; Liu, Y.; McNally, K.; Gaur, A.; Coventry, B.; Chen, W.; Bera, A. K.; Kang, A.; Gerben, S.; Lamb, M. Y.-L.; Murray, A.; Li, X.; Kennedy, M. A.; Yang, W.; Schober, G.; Brierley, S. M.; Gelb, M. H.; Montelione, G. T.; Derivery, E.; Baker, D.
10.1101/2024.07.15.603480 — biochemistry — Posted on 2024-09-02
5334 Potent LILRB1 D1D2-containing antibodies inhibit RIFIN-mediated immune evasions
Wang, Y.; Tang, H.; Wang, W.; Li, M.; Zhu, C.; Dai, H.; Zhao, H.; Wu, B.; Wang, J.
10.1101/2024.08.08.607148 — biochemistry — Posted on 2024-09-02
5336 The utility of whole-genome sequencing to identify likely transmission pairs for pathogens with slow and variable evolution
Wood, A. J.; Benton, C. H.; Delahay, R. J.; Marion, G.; Palkopoulou, E.; Pooley, C. M.; Kao, R. R.
10.1101/2024.05.06.592672 — ecology — Posted on 2024-09-02
5337 In situ generation of Aβ42 oligomers via secondary nucleation triggers neurite degeneration and synaptic dysfunction in human iPSC-derived glutamatergic neurons
Gonzalez-Diaz, A.; Sarracco, E.; Possenti, A.; Kitchen-Smith, I.; Chia, S.; Menzies, J.; Stephenson, G.; Cataldi, R.; Yahya, K.; Bian, Y.; Urrutia, G. A.; Linse, S.; Mannini, B.; Vendruscolo, M.
10.1101/2024.08.30.610591 — cell biology — Posted on 2024-09-02
5338 Comparing arm to whole-body motor control disambiguates age-related deterioration from compensation
Mathieu, R.; Chambellant, F.; Thomas, E.; Papaxanthis, C.; Hilt, P.; Manckoundia, P.; Mourey, F.; Gaveau, J.
10.1101/2024.02.16.576683 — neuroscience — Posted on 2024-09-02
5339 Convergent and lineage-specific genomic changes contribute to adaptations in sugar-consuming birds
Osipova, E.; Ko, M.-C.; Petricek, K. M.; Yung Wa Sin, S.; Brown, T.; Winkler, S.; PIppel, M.; Jarrells, J.; Weiche, S.; Mosbech, M.-B.; Taborsak-Lines, F.; Wang, C.; Contreras-Lopez, O.; Olsen, R.-A.; Ewels, P.; Mendez Aranda, D.; Gaede, A.; Sadanandan, K.; Weijie Low, G.; Monte, A.; Ballerstaedt, N.; Adreani, N. M.; Mentesana, L.; von Bayern, A.; Rico-Guevara, A.; Edwards, S.; Altshuler, D.; Buttemer, W. A.; Frankl-Vilches, C.; Kuhl, H.; Bakker, A.; Gahr, M.; Schupp, M.; Baldwin, M. W.; Hiller, M.; Sackton, T. B.
10.1101/2024.08.30.610474 — evolutionary biology — Posted on 2024-09-01
5345 Negative feedback of cyclic di-GMP levels optimizes switching between sessile and motile lifestyles in Vibrio cholerae
Rangarajan, A. A.; Schroeder, J. W.; Hurto, R. L.; Severin, G. B.; Pell, M. E.; Hsieh, M.-L.; Waters, C. M.; Freddolino, L.
10.1101/2024.09.01.610008 — microbiology — Posted on 2024-09-01
5346 Genome-wide CRISPRi-seq identified ferredoxin-NADP reductase FprB as a synergistic target for gallium therapy in Pseudomonas aeruginosa
Liu, X.; Zhang, Y.; Zhang, T.; Xiao, X.; Kawalek, A.; Ou, J.; Ren, A.; Sun, W.; Bakker, V. d.; Liu, Y.; Li, Y.; Yang, L.; Ye, L.; Jia, N.; Veening, J.-W.; Wang, Y.
10.1101/2024.09.01.610675 — microbiology — Posted on 2024-09-01
5354 Reciprocal regulation of m6A modification and miRNA production machineries via phase separation-dependent and -independent mechanisms
Zhong, S.; Li, X.; Li, C.; Bai, H.; Chen, J.; Gan, L.; Zhu, J.; Oh, T.; Yan, X.; Zhu, J.; Li, N.; Koiwa, H.; Meek, T.; Peng, X.; Yu, B.; Zhang, Z.; Zhang, X.
10.1101/2024.08.31.610644 — plant biology — Posted on 2024-09-01
5355 AMOEBA Polarizable Molecular Dynamics Simulations of Guanine Quadruplexes: from the c-Kit Proto-oncogene to HIV-1
El Ahdab, D. S.; Lagardere, L.; Hobaika, Z.; Jaffrelot Inizan, T.; Celerse, F.; Gresh, N.; Maroun, R. G.; Piquemal, J.-P.
10.1101/2024.08.28.610081 — biophysics — Posted on 2024-09-01
5356 Performance of qpAdm-based screens for genetic admixture on admixture-graph-shaped histories and stepping-stone landscapes
Flegontova, O.; Isıldak, U.; Yüncü, E.; Williams, M. P.; Huber, C. D.; Koci, J.; Vyazov, L. A.; Changmai, P.; Flegontov, P.
10.1101/2023.04.25.538339 — genetics — Posted on 2024-09-01
5357 How air temperature and solar radiation impact life history traits in a wild insect
Gardner, A. S.; Maclean, I. M. D.; Rodriguez-Munoz, R.; Ojanguren, A. F.; Tregenza, T.
10.1101/2024.08.13.607703 — evolutionary biology — Posted on 2024-09-01
5358 Isotope analysis of bird eye lens provides early-life information
Hasegawa, E. A.; Matsubayashi, J.; Tayasu, I.; Goto, T.; Inoue, H.; Rossberg, A. G.; Yoshimizu, C.; Hasegawa, M.; Akasaka, T.
10.1101/2024.08.28.610164 — ecology — Posted on 2024-09-01
5359 Predicting cell cycle stage from 3D single-cell nuclear-stained images
Li, G.; Nichols, E. K.; Browning, V. E.; Longhi, N. J.; Camplisson, C.; Beliveau, B. J.; Noble, W. S.
10.1101/2024.08.30.610553 — cell biology — Posted on 2024-09-01
5360 Astrocyte-derived MFG-E8 facilitates microglial synapse elimination in Alzheimer's disease mouse models
Sokolova, D.; Addington Ghansah, S.; Puletti, F.; Georgiades, T.; De Schepper, S.; Zheng, Y.; Crowley, G.; Wu, L.; Rueda-Carrasco, J.; Koutsiouroumpa, A.; Muckett, P.; Freeman, O. J.; Khakh, B. S.; Hong, S.
10.1101/2024.08.31.606944 — neuroscience — Posted on 2024-09-01
5362 Increasing adult-born neurons protects mice from epilepsy.
Jain, S.; LaFrancois, J. J.; Gerencer, K.; Botterill, J. J.; Kennedy, M.; Criscuolo, C.; Scharfman, H.
10.1101/2023.07.08.548217 — neuroscience — Posted on 2024-09-01
5363 Subcellular proteomics and iPSC modeling uncover reversible mechanisms of axonal pathology in Alzheimer's disease
Cai, Y.; Kanyo, J.; Wilson, R.; Bathla, S.; Cardozo, P. L.; Tong, L.; Qin, S.; Fuentes, L. A.; Pinheiro-de-Sousa, I.; Huynh, T.; Sun, L.; Mansuri, M. S.; Tian, Z.; Gan, H.-R.; Braker, A.; Trinh, H. K.; Lam, T.; Petsalaki, E.; Brennand, K.; Nairn, A. C.; Grutzendler, J.
10.1101/2022.09.30.510408 — neuroscience — Posted on 2024-09-01
5364 The ultrasonic vocalization (USV) syllable profile during neonatal opioid withdrawal and a kappa opioid receptor component to increased USV emissions in female mice
Wingfield, K. K.; Misic, T.; Jain, K.; McDermott, C. S.; Abney, N. M.; Richardson, K. T.; Rubman, M. B.; Beierle, J. A.; Miracle, S. A.; Sandago, E. J.; Baskin, B. M.; Lynch, W. B.; Borrelli, K. N.; Yao, E. J.; Wachman, E. M.; Bryant, C. D.
10.1101/2024.07.02.601766 — neuroscience — Posted on 2024-09-01
5365 Inhibition of PAK2 in endothelial cells suppresses tumor angiogenesis and promotes immune sensitization through CXCL10
Corriveau, J.; Monot, P.; Delisle, C.; Goyette, M.-A.; Gasse, C.; El Bakkouri, Y.; Hoang, T.; Cote, J.-F.; Gratton, J.-P.
10.1101/2024.04.05.588280 — cancer biology — Posted on 2024-09-01
5367 Synaptic imbalance and increased inhibition impair motor function in SMA
Fletcher, E. V.; Chalif, J. I.; Rotterman, T. M.; Pagiazitis, J. G.; Van Alstyne, M.; Sivakumar, N.; Rabinowitz, J. E.; Pellizzoni, L.; Alvarez, F. J.; Mentis, G. Z.
10.1101/2024.08.30.610545 — neuroscience — Posted on 2024-09-01
5370 Engineering asymmetric nanoscale lipid vesicles for drug delivery
Yang, C.; Menge, J.; Zhvania, N.; Chen, D.; Weitz, D. A.; Jahnke, K.
10.1101/2024.08.30.610290 — biophysics — Posted on 2024-09-01
5377 Wirelessly-Powered Ingestible Electronic Capsule for Non-invasive Gastrointestinal Optogenetics
Elsherif, M.; El-Din, R. B.; Makhambetova, Z.; Naser, H.; Boitet, M.; Singh, R.; Oh, K.; Sukesan, R.; Ha, S.; Ramadi, K. B.
10.1101/2024.08.30.610532 — bioengineering — Posted on 2024-09-01
5381 Unbiased preclinical phenotyping reveals neuroprotective properties of pioglitazone
Harding, E. C.; Chen, H.-J. C.; Shepilov, D.; Zhang, S. O.; Rowley, C.; Mali, I.; Chen, J.; Stewart, N.; Swinden, D.; Washer, S. J.; Bassett, A. R.; Merkle, F. T.
10.1101/2024.08.30.610328 — neuroscience — Posted on 2024-09-01
5385 Neural Basis of Number Sense in Larval Zebrafish
Luu, P.; Nadtochiy, A.; Zanon, M.; Moreno, N.; Messina, A.; Petrazzini, M. E. M.; Torres-Perez, J. V.; Jones, M.; Keomanee-Dizon, K.; Brennan, C. H.; Vallortigara, G.; Fraser, S. E.; Truong, T. V.
10.1101/2024.08.30.610552 — neuroscience — Posted on 2024-09-01
5390 Sec18 side-loading is essential for universal SNARE recycling across cellular contexts
Khan, Y. A.; White, K. I.; Pfuetzner, R. A.; Singal, B.; Esquivies, L.; Mckenzie, G.; Liu, F.; DeLong, K.; Choi, U.; Montabana, E.; Mclaughlin, T.; Wickner, W.; Brunger, A. T.
10.1101/2024.08.30.610324 — biophysics — Posted on 2024-09-01
5392 Leveraging Multi-Modal Feature Learning for Predictions of Antibody Viscosity
Anapindi, K. D. B.; Liu, K.; Wang, W.; Yu, Y.; He, Y.; Hsieh, E. J.; Huang, Y.; Tomazela, D.
10.1101/2024.08.30.610550 — bioinformatics — Posted on 2024-09-01
5393 Increased burden of rare risk variants across gene expression networks predisposes to sporadic Parkinson's disease
Eubanks, E.; VanderSleen, K.; Mody, J.; Patel, N.; Sacks, B.; Darestani Farahani, M.; Wang, J.; Elliott, J.; Jaber, N.; Akcimen, F.; Bandres-Ciga, S.; Helweh, F.; Liu, J.; Archakam, S.; Kimelman, R.; Sharma, B.; Socha, P.; Guntur, A.; Bartels, T.; Dettmer, U.; Mouradian, M. M.; Bahrami, A. H.; Dai, W.; Baum, J.; Shi, Z.; Hardy, J.; Kara, E.
10.1101/2024.08.30.610195 — cell biology — Posted on 2024-09-01
5394 In situ generation of Aβ42 oligomers via secondary nucleation triggers neurite degeneration and synaptic dysfunction in human iPSC-derived glutamatergic neurons
Gonzalez-Diaz, A.; Sarracco, E.; Possenti, A.; Kitchen-Smith, I.; Chia, S.; Menzies, J.; Stephenson, G.; Cataldi, R.; Yahya, K.; Bian, Y.; Urrutia, G. A.; Linse, S.; Mannini, B.; Vendruscolo, M.
10.1101/2024.08.30.610591 — cell biology — Posted on 2024-09-01
5395 Validation studies and multi-omics analysis of Zhx2 as a candidate quantitative trait gene underlying brain oxycodone metabolite (oxymorphone) levels and behavior
Lynch, W. B.; Miracle, S. A.; Goldstein, S. I.; Beierle, J. A.; Bhandari, R.; Gerhardt, E. T.; Farnan, A.; Nguyen, B.-M.; Wingfield, K. K.; Kazerani, I.; Saavedra, G. A.; Averin, O.; Baskin, B. M.; Ferris, M. T.; Reilly, C. A.; Emili, A.; Bryant, C. D.
10.1101/2024.08.30.610534 — neuroscience — Posted on 2024-09-01
5397 Bronchopulmonary Dysplasia with Pulmonary Hypertension Associates with Loss of Semaphorin Signaling and Functional Decrease in FOXF1 Expression
Shirazi, S. P.; Negretti, N. M.; Jetter, C. S.; Sharkey, A. L.; Garg, S.; Kapp, M. E.; Wilkins, D.; Fortier, G.; Mallapragada, S.; Banovich, N.; Wright, C. V. E.; Frank, D. B.; Kropski, J. A.; Sucre, J. M. S.
10.1101/2024.08.27.609955 — genomics — Posted on 2024-09-01
5398 Parallel genome-scale CRISPR-Cas9 screens uncouple human pluripotent stem cell identity versus fitness
Rosen, B. P.; Li, Q. V.; Cho, H. S.; Liu, D.; Yang, D.; Graff, S.; Yan, J.; Luo, R.; Verma, N.; Damodaran, J. R.; Kale, H. T.; Kaplan, S. J.; Beer, M. A.; Sidoli, S.; Huangfu, D.
10.1101/2023.05.03.539283 — developmental biology — Posted on 2024-09-01
5403 Predicting cell cycle stage from 3D single-cell nuclear-stained images
Noble, W. S.; Beliveau, B. J.; Li, G.; Nichols, E. K.; Browning, V. E.; Longhi, N. J.; Camplisson, C.
10.1101/2024.08.30.610553 — cell biology — Posted on 2024-09-01
5406 Temporal control of acute protein aggregate turnover by UBE3C and NRF1-dependent proteasomal pathways
Hickey, K. L.; Panov, A.; Whelan, E. M.; Schaefer, T.; Mizrak, A.; Kopito, R. R.; Baumeister, W.; Fernandez-Busnadiego, R.; Harper, W.
10.1101/2024.08.30.610524 — cell biology — Posted on 2024-09-01
5407 CHCHD2 mutant mice display mitochondrial protein accumulation and disrupted energy metabolism
Liao, S.-C.; Kano, K.; Phanse, S.; Nguyen, M.; Margolis, E. B.; Fu, Y.; Meng, J.; Moutaoufik, M. T.; Chatterton, Z.; Aoki, H.; Simms, J.; Hsieh, I.; Suteja, F.; Sei, Y.; Huang, E. J.; McAvoy, K.; Manfredi, G.; Halliday, G.; Babu, M.; Nakamura, K.
10.1101/2024.08.30.610586 — neuroscience — Posted on 2024-09-01
5409 The human hippocampus is involved in implicit motor learning
Griffa, G.; Deleglise, A.; Solano, A.; Jacobacci, F.; De Pino, G.; Della-Maggiore, V.
10.1101/2024.08.30.610548 — neuroscience — Posted on 2024-09-01
5410 Neuronal firing rate diversity lowers the dimension of population covariability
Tian, G. J.; Zhu, O.; Shirhatti, V.; Greenspon, C.; Downey, J. E.; Freedman, D. J.; Doiron, B.
10.1101/2024.08.30.610535 — neuroscience — Posted on 2024-09-01
5411 Sample Size Impact (SaSii): an R script for estimating optimal sample sizes in population genetics and population genomics studies
Scaketti, M.; Sujii, P. S.; Alves-Pereira, A.; Schwarcz, K. D.; Francisconi, A. F.; Moro, M. S.; Martins, K. K. M.; de Jesus, T. A.; de Souza, G. B. F.; Zucchi, M. I.
10.1101/2024.08.30.610119 — bioinformatics — Posted on 2024-09-01
5415 Noradrenaline causes a spread of association in the hippocampal cognitive map
Koolschijn, R. S.; Browning, M.; Clarke, W. T.; O'Reilly, J. X.; Barron, H. C.
10.1101/2024.08.31.610602 — neuroscience — Posted on 2024-09-01