bioRxiv directory

1 Species-specific developmental timing is associated with global differences in protein stability in mouse and human

Rayon, T.; Stamataki, D.; Perez-Carrasco, R.; Garcia-Perez, L.; Barrington, C.; Melchionda, M.; Exelby, K.; Tybulewicz, V.; Fisher, E. M. C.; Briscoe, J.

10.1101/2019.12.29.889543 — developmental biology — Posted on 2019-12-31

2 Binary and analog variation of synapses between cortical pyramidal neurons

Dorkenwald, S.; Turner, N. L.; Macrina, T.; Lee, K.; Lu, R.; Wu, J.; Bodor, A. L.; Bleckert, A. A.; Brittain, D.; Kemnitz, N.; Silversmith, W. M.; Ih, D.; Zung, J.; Zlateski, A.; Tartavull, I.; Yu, S.-C.; Popovych, S.; Wong, W.; Castro, M.; Jordan, C.; Wilson, A. M.; Froudarakis, E.; Buchanan, J.; Takeno, M.; Torres, R.; Mahalingam, G.; Collman, F.; Schneider-Mizell, C.; Bumbarger, D. J.; Li, Y.; Becker, L.; Suckow, S.; Reimer, J.; Tolias, A. S.; da Costa, N. M.; Reid, R. C.; Seung, H. S.

10.1101/2019.12.29.890319 — neuroscience — Posted on 2019-12-31

3 Two C-terminal sequence variations determine differential neurotoxicity between human and mouse α-synuclein

Landeck, N.; Strathearn, K. E.; Ysselstein, D.; Buck, K.; Dutta, S.; Banerjee, S.; Lv, Z.; Hulleman, J. D.; Hindupur, J.; Lin, L.-K.; Padalkar, S.; McCabe, G. P.; Stanciu, L. A.; Lyubchenko, Y. L.; Kirik, D.; Rochet, J.-C.

10.1101/700377 — neuroscience — Posted on 2019-12-31

4 Comparative genomic analysis of Cristatella mucedo provides insights into Bryozoan evolution and nervous system function

Starunov, V. V.; Predeus, A. V.; Barbitoff, Y. A.; Kutiumov, V. A.; Maltseva, A. L.; Vodiasova, E. A.; Kohn, A. B.; Moroz, L. L.; Ostrovsky, A. N.

10.1101/869792 — genomics — Posted on 2019-12-31

5 Twelve Platinum-Standard Reference Genomes Sequences (PSRefSeq) that complete the full range of genetic diversity of Asian rice

Zhou, Y.; Chebotarov, D.; Kudrna, D.; Llaca, V.; Lee, S.; Rajasekar, S.; Mohammed, N.; Al-Bader, N.; Sobel-Sorenson, C.; Parakkal, P.; Arbelaez, L. J.; Franco, N.; Alexandrov, N.; Hamilton, N. R. S.; Leung, H.; Mauleon, R.; Lorieux, M.; Zuccolo, A.; McNally, K.; Zhang, J.; Wing, R. A.

10.1101/2019.12.29.888347 — genomics — Posted on 2019-12-31

6 Characterization of protein-ligand binding interactions of enoyl-ACP reductase (FabI) by native MS reveals allosteric effects of coenzymes and the inhibitor triclosan

Joyner, P. M.; Tran, D. P.; Zenaidee, M. A.; Loo, J. A.

10.1101/2019.12.30.891283 — biochemistry — Posted on 2019-12-31

7 Insights from Comparison of the Renal and Skin Single Cell Transcriptomes in Lupus Nephritis

Der, E.; Suryawanshi, H.; Morozov, P.; Kustagi, M.; Goilav, B.; Ranabathou, S.; Izmirly, P.; Clancy, R.; Belmont, H. M.; Koenigsberg, M.; Mokrzycki, M.; Rominieki, H.; Graham, J.; Rocca, J.; Bornkamp, N.; Jordan, N.; Schulte, E.; Wu, M.; Pullman, J.; Slowikowski, K.; Raychaudhuri, S.; Guthridge, J.; James, J.; Acclerating Medicine Partnership (AMP), ; Buyon, J.; Tuschl, T.; Putterman, C.

10.1101/382846 — immunology — Posted on 2019-12-31

8 Ancestral neural computations constrain the evolution of novel computations in simulated color vision networks

Buerkle, N. P.; Palmer, S. E.

10.1101/2019.12.30.891382 — neuroscience — Posted on 2019-12-31

9 Effect of high frequency and low intensity pulsed electric field on protecting SH-SY5Y cells against hydrogen peroxide and β-amyloid-induced cell injury via ERK pathway

Chen, W.-T.; Lin, G.-B.; Kuo, Y.-Y.; Hsieh, C.-H.; Lu, C.-H.; Sun, Y.-K.; Chao, C.-Y.

10.1101/2019.12.30.891499 — neuroscience — Posted on 2019-12-31

10 SMALL ALPHAHERPESVIRUS LATENCY-ASSOCIATED PROMOTERS DRIVE EFFICIENT AND LONG-TERM TRANSGENE EXPRESSION IN THE CENTRAL NERVOUS SYSTEM

Maturana, C. J.; Verpeut, J. L.; Pisano, T. J.; Dhanerawala, Z. M.; Esteves, A.; Enquist, L. W.; Engel, E. A.

10.1101/2019.12.31.891903 — neuroscience — Posted on 2019-12-31

11 A translational kidney organoid system bolsters human relevance of clinical development candidate

Westerling-Bui, A. D.; Soare, T. W.; Venkatachalan, S.; DeRan, M.; Fast, E. M.; Fanelli, A. B.; Kyrychenko, S.; Hoang, H.; Corriea, G. M.; Zhang, W.; Yu, M.; Daniels, M.; Malojcic, G.; Pan-Zhou, X.-R.; Ledeboer, M. W.; Harmange, J.-C.; Emani, M.; Tibbitts, T. T.; Reilly, J. F.; Mundel, P.

10.1101/2019.12.30.891440 — genomics — Posted on 2019-12-31

12 The tortoise strategy as an arbovirus fitness phenotype within the mosquito as revealed by a novel formulation of age-structured vectorial capacity

Mayton, E. H.; Wearing, H. J.; Tramonte, A. R.; Christofferson, R. C.

10.1101/552125 — ecology — Posted on 2019-12-31

13 Single molecule tracking reveals the role of transitory dynamics of nucleoid-associated protein HU in organizing the bacterial chromosome

Bettridge, K.; Verma, S.; Weng, X.; Adhya, S.; Xiao, J.

10.1101/2019.12.31.725226 — biophysics — Posted on 2019-12-31

14 Dynamic multimodal interactions in navigating wood ants: What do path details tell us about cue integration?

Buehlmann, C.; Aussel, A.; Graham, P.

10.1101/2019.12.31.891689 — animal behavior and cognition — Posted on 2019-12-31

15 poly(UG)-tailed RNAs in Genome Protection and Epigenetic Inheritance

Shukla, A.; Yan, J.; Pagano, D. J.; Dodson, A. E.; Fei, Y.; Gorham, J.; Seidman, J. G.; Wickens, M.; Kennedy, S.

10.1101/2019.12.31.891960 — molecular biology — Posted on 2019-12-31

16 Acetylation is required for NLRP3 self-aggregation and full activation of the inflammasome

Zhao, K.; Zhang, Y.; Xu, X.; Liu, L.; Huang, L.; Luo, R.; Li, J.; Zhang, N.; Lu, B.

10.1101/2019.12.31.891556 — immunology — Posted on 2019-12-31

17 Determinants of growth and body size in Austrolebias South-American annual killifish

Helmstetter, A. J.; Van Dooren, T. J.

10.1101/2019.12.31.891648 — evolutionary biology — Posted on 2019-12-31

18 Single cell epigenomic atlas of the developing human brain and organoids

Ziffra, R. S.; Kim, C. N.; Wilfert, A.; Haeussler, M.; Casella, A. M.; Przytycki, P. F.; Kreimer, A.; Pollard, K. S.; Ament, S. A.; Eichler, E. E.; Ahituv, N.; Nowakowski, T. J.

10.1101/2019.12.30.891549 — developmental biology — Posted on 2019-12-31

19 Accuracy and Reproducibility of Somatic Point Mutation Calling in Clinical-Type Targeted Sequencing Data

Karimnezhad, A.; Palidwor, G. A.; Thavorn, K.; Stewart, D. J.; Campbell, P. A.; Lo, B.; Perkins, T. J.

10.1101/2019.12.31.891952 — bioinformatics — Posted on 2019-12-31

20 Prediction-based highly sensitive CRISPR off-target validation using target-specific DNA enrichment

Lee, S. H.; Kim, S.-U.; Hur, J. K.; Kang, S.-H.; Lee, W.-j.; An, J.-H.; Lee, J.-H.; Kim, Y.-H.; Kim, H.; Oh, Y.; Park, Y.-H.; Jin, Y. B.; Jun, B.-H.

10.1101/2019.12.31.889626 — molecular biology — Posted on 2019-12-31

21 The color appearance of three-dimensional, curved, transparent objects

Ennis, R.; Doerschner, K.

10.1101/2019.12.30.891341 — neuroscience — Posted on 2019-12-31

22 Synergic coordination of stem cells is required to induce a regenerative response in anthozoan cnidarians

Amiel, A. R.; Foucher, K.; Ferreira, S.; Rottinger, E.

10.1101/2019.12.31.891804 — developmental biology — Posted on 2019-12-31

23 Deep evolutionary analysis reveals the design principles of fold A glycosyltransferases

Taujale, R.; Venkat, A.; Huang, L.-C.; Yeung, W.; Rasheed, K.; Edison, A. S.; Moremen, K. W.; Kannan, N.

10.1101/2019.12.31.891697 — bioinformatics — Posted on 2019-12-31

24 A Splice Site-Sensing Conformational Switch in U2AF2 is Modulated by U2AF1 and its Recurrent Myelodysplasia-Associated Mutation

Kielkopf, C. L.; Ermolenko, D. N.; Jenkins, J. L.; Laird, K. M.; Feeney, C. F.; Glasser, E.; Warnasooriya, C.

10.1101/2019.12.31.891358 — biochemistry — Posted on 2019-12-31

25 Regulation of Prefrontal Patterning, Connectivity and Synaptogenesis by Retinoic Acid

Shibata, M.; Pattabiraman, K.; Lorente-Galdos, B.; Andreijevic, D.; Xing, X.; Sousa, A. M. M.; Santpere, G.; Sestan, N.

10.1101/2019.12.31.891036 — neuroscience — Posted on 2019-12-31

26 Hominini-Specific Regulation of CBLN2 Increases Prefrontal Synaptogenesis

Shibata, M.; Pattabiraman, K.; Muchnik, S. K.; Sestan, N.

10.1101/2019.12.31.891069 — neuroscience — Posted on 2019-12-31

27 Movement-assisted localization from acoustic telemetry data

Hostetter, N. J.; Royle, J. A.

10.1101/2019.12.31.890962 — ecology — Posted on 2019-12-31

28 RaptRanker: in silico RNA aptamer selection from HT-SELEX experiment based on local sequence and structure information

Ishida, R.; Adachi, T.; Yokota, A.; Yoshihara, H.; Aoki, K.; Nakamura, Y.; Hamada, M.

10.1101/2019.12.31.890392 — bioinformatics — Posted on 2019-12-31

29 Designing signaling environments to steer transcriptional diversity in neural progenitor cell populations

Chen, S.; Thomson, M.; Park, J. H.; Tsou, T.; Rivaud, P.

10.1101/2019.12.30.890087 — systems biology — Posted on 2019-12-31

30 A Stochastic Model for Actin Waves in Eukaryotic Cells

Hu, J.; Khamviwath, V.; Othmer, H.

10.1101/2019.12.31.892034 — systems biology — Posted on 2019-12-31

31 What influences treatment response in animal models of non-alcoholic fatty liver disease? A meta-analysis with meta-regression.

Hunter, H.; de Gracia Hahn, D.; Duret, A.; Im, Y. R.; Cheah, Q.; Dong, J.; Fairey, M.; Hjalmarsson, C.; Li, A.; Lim, H. K.; McKeown, L.; Mitrofan, C.-G.; Rao, R.; Utukuri, M.; Rowe, I. A.; Mann, J. P.

10.1101/2019.12.31.887919 — physiology — Posted on 2019-12-31

32 Valeriana Officinalis Crude Extracts Impair Hair Cell Regeneration in Larval Zebrafish Lateral Line

Rodriguez-Morales, R.; Santana-Cruz, A.; Tossas-Deida, T.; Torrado-Tapias, A.; Behra, M.

10.1101/2019.12.30.891366 — pharmacology and toxicology — Posted on 2019-12-31

33 An optimality principle for locomotor central pattern generators

Ryu, H. X.; Kuo, A. D.

10.1101/2019.12.30.890152 — neuroscience — Posted on 2019-12-31

34 Endothelial JAK2V617F mutation leads to thrombosis, vasculopathy, and cardiomyopathy in a murine model of myeloproliferative neoplasm

Castiglione, M.; Mazzeo, C.; Jiang, Y.-P.; Chen, J.-S.; Kaushansky, K.; Yin, W.; Lin, R.; Zheng, H.; Zhan, H.

10.1101/2019.12.31.891721 — molecular biology — Posted on 2019-12-31

35 Auxin-dependent alleviation of oxidative stress and growth promotion of Scenedesmus obliquus C1S by Azospirillum brasilense

Pagnussat, L. A.; Maroniche, G. A.; Curatti, L.; Creus, C.

10.1101/2019.12.31.891424 — microbiology — Posted on 2019-12-31

36 Quality assessment of single-cell RNA sequencing data by coverage skewness analysis

Abugessaisa, I.; Noguchi, S.; Cardon, M.; Hasegawa, A.; Watanabe, K.; Takahashi, M.; Suzuki, H.; Katayama, S.; Kere, J.; Kasukawa, T.

10.1101/2019.12.31.890269 — genomics — Posted on 2019-12-31

37 Stock mislabelling and its impact on phylogenomic analysis in the Drosophila nasuta subgroup/species complex

Waddell, P. J.; Wang, J.; Jones, C.

10.1101/2019.12.30.891523 — evolutionary biology — Posted on 2019-12-31

38 Sequence representations and their utility for predicting protein-protein interactions

Kimothi, D.; Biyani, P.; Hogan, J. M.

10.1101/2019.12.31.890699 — bioinformatics — Posted on 2019-12-31

39 MONN: a Multi-Objective Neural Network for Predicting Pairwise Non-Covalent Interactions and Binding Affinities between Compounds and Proteins

Li, S.; Wan, F.; Shu, H.; Jiang, T.; Zhao, D.; Zeng, J.

10.1101/2019.12.30.891515 — bioinformatics — Posted on 2019-12-31

40 Identifying and engineering ancient variants of enzymes using Graphical Representation of Ancestral Sequence Predictions (GRASP)

Foley, G.; Mora, A.; Ross, C. M.; Bottoms, S.; Sutzl, L.; Lamprecht, M. L.; Zaugg, J.; Essebier, A.; Balderson, B.; Newell, R.; Thomson, R. E.; Kobe, B.; Barnard, R. T.; Guddat, L.; Schenk, G.; Carsten, J.; Gumulya, Y.; Rost, B.; Haltrich, D.; Sieber, V.; Gillam, E. M.; Boden, M.

10.1101/2019.12.30.891457 — bioinformatics — Posted on 2019-12-31

41 Bacteria contribute to mosquito development via folate biosynthesis and energy storage

Romoli, O.; Schonbeck, J. C.; Hapfelmeier, S.; Gendrin, M.

10.1101/2019.12.31.891671 — developmental biology — Posted on 2019-12-31

42 Effect of Exogenous Amino Acids on Yield and Quality of Tartary Buckwheat in Non-saline and Saline-alkali Soil

Song, J.-N.; Wang, Y.-Q.; Li, S.; Li, F.-L.; Hu, Y.-J.; Yang, H.-B.

10.1101/2019.12.24.887778 — physiology — Posted on 2019-12-31

43 Easily phylotyping E. coli via the EzClermont web app and command-line tool.

Waters, N.; Brennan, F.; Holmes, A.; Abram, F.; Pritchard, L.

10.1101/317610 — bioinformatics — Posted on 2019-12-31

44 A novel mouse model of cholangiocarcinoma uncovers a role for a SOX17-Tensin 4 pathway in tumor progression

Di-Luoffo, M.; Pirenne, S.; Saandi, T.; Loriot, A.; Gerard, C.; Dauguet, N.; Lamoline, F.; Konobrocka, K.; De Greef, V.; Komuta, M.; Jacquemin, P.; Lemaigre, F. P.

10.1101/870212 — cancer biology — Posted on 2019-12-31

45 Comparative Genomics Shows Differences in the Electron Transport and Carbon Metabolic Pathways of Mycobacterium africanum relative to Mycobacterium tuberculosis and suggests an adaptation to low oxygen tension

Ofori-Anyinam, A. B.; Riley, A.; Jobarteh, T.; Gitteh, E.; Sarr-Kuyateh, B.; Faal-Jawara, T. I.; Rigouts, L.; Senghore, M.; Kehinde, A.; Onyejepu, N.; Antonio, M.; C. de Jong, B.; Gehre, F.; Meehan, C. J.

10.1101/792762 — microbiology — Posted on 2019-12-31

46 Fibronectin-dependent tissue mechanics regulate the translation of segmentation clock oscillations into periodic somite formation

Gomes de Almeida, P.; Rifes, P.; Martins-Jesus, A. P.; Pinheiro, G. G.; Andrade, R. P.; Thorsteinsdottir, S.

10.1101/808121 — developmental biology — Posted on 2019-12-31

47 Comparing the utility of in vivo transposon mutagenesis approaches in yeast species to infer gene essentiality

Levitan, A.; Gale, A. N.; Dalton, E. K.; Kozan, D. W.; Cunningham, K. W.; Sharan, R.; Berman, J.

10.1101/732552 — bioinformatics — Posted on 2019-12-31

48 The importance of cellular-scale viral dynamics in bat reservoirs for emerging zoonotic disease

Brook, C. E.; Boots, M.; Chandran, K.; Dobson, A. P.; Drosten, C.; Graham, A. L.; Grenfell, B.; Müller, M. A.; Ng, M.; Wang, L.-F.; van Leeuwen, A.

10.1101/696195 — ecology — Posted on 2019-12-31

49 A potential hydrodynamic mechanism for cytoplasmic transfer between mammalian cells: Cell-projection pumping

Zoellner, H.; Paknejad, N.; Cornwell, J.; Chami, B.; Romin, Y.; Boyko, V.; Fujisawa, S.; Kelly, E.; Lynch, G. W.; Rogers, G.; Manova, K.; Moore, M. A.

10.1101/531798 — cell biology — Posted on 2019-12-31

50 Identification of a novel therapeutic agent for Inflammatory Bowel Disease guided by systems medicine

Lloyd, K.; Papoutsopoulou, S.; Smith, E.; Stegmaier, P.; Bergey, F.; Morris, L.; Kittner, M.; England, H.; Spiller, D.; White, M. H.; Duckworth, C. A.; Campbell, B. J.; Poroikov, V.; Martins dos Santos, V.; Kel, A.; Müller, W.; Pritchard, D. M.; Probert, C.; Burkitt, M.; The SysmedIBD Consortium,

10.1101/513838 — systems biology — Posted on 2019-12-31

51 An instrument to assess HIV-related knowledge and adjustment to HIV+ status, and their association with anti-retroviral adherence

Laws, M. B.; Lee, Y.; Rogers, W. S.; Taubin, T.; Wilson, I. B.

10.1101/2019.12.30.890822 — scientific communication and education — Posted on 2019-12-30

52 Activation of the hypothalamic-pituitary adrenal axis in response to a verbal fluency task and associations with task performance

Becker, L.; Schade, U.; Rohleder, N.

10.1101/2019.12.30.890814 — physiology — Posted on 2019-12-30

53 Higher cognitive reserve is associated with better neural efficiency in the cognitive performance of young adults. An event-related potential study

Gutierrez-Zamora, G.; Fernandez, T.; Silva-Pereyra, J.; Reynoso-Alcantara, V.

10.1101/2019.12.30.890830 — neuroscience — Posted on 2019-12-30

54 Rev-erba heterozygosity produces a dose-dependent phenotypic advantage in mice

Welch, R. D.; Billon, C.; Burris, T. P.; Flaveny, C. A.

10.1101/2019.12.30.890806 — molecular biology — Posted on 2019-12-30

55 Gut-derived Flavonifractor species variants are differentially enriched during in vitro incubation with quercetin

Rodriguez Castano, G. P.; Rey, F. E.; Caro-Quintero, A.; Acosta-Gonzalez, A.

10.1101/2019.12.30.890848 — microbiology — Posted on 2019-12-30

56 Temperature sensitive Mutant Proteome Profiling: a novel tool for the characterization of the global impact of missense mutations on the proteome

Peck Justice, S. A.; Qi, G.; Wijeratne, H. R. S.; Victorino, J. F.; Simpson, E. R.; Wijeratne, A. B.; Mosley, A. L.

10.1101/2019.12.30.891267 — systems biology — Posted on 2019-12-30

57 Enhancing Intracellular Concentration and Target Engagement of PROTACs with Reversible Covalent Chemistry

Guo, W.-H.; Qi, X.; Liu, Y.; Chung, C.-I.; Bai, F.; Lin, X.; Wang, L.; Chen, J.; Nomie, K. J.; Li, F.; Wang, M. C.; Shu, X.; Onuchic, J. N.; Woyach, J. A.; Wang, M. L.; Wang, J.

10.1101/2019.12.30.873588 — pharmacology and toxicology — Posted on 2019-12-30

58 A possible coding for experience: ripple-like events and synaptic diversity

Ishikawa, J.; Tomokage, T.; Mitsushima, D.

10.1101/2019.12.30.891259 — animal behavior and cognition — Posted on 2019-12-30

59 Meta-Learning Biologically Plausible Semi-Supervised Update Rules

Gu, K.; Greydanus, S.; Metz, L.; Maheswaranathan, N.; Sohl-Dickstein, J.

10.1101/2019.12.30.891184 — neuroscience — Posted on 2019-12-30

60 The pattern of Nodal morphogen signaling is shaped by co-receptor expression

Lord, N. D.; Carte, A. N.; Abitua, P. B.; Schier, A. F.

10.1101/2019.12.30.891101 — developmental biology — Posted on 2019-12-30

61 Insights into functional connectivity in mammalian signal transduction pathways by pairwise comparison of protein interaction partners of critical signaling hubs

Chilakamarti, R.

10.1101/2019.12.30.891200 — bioinformatics — Posted on 2019-12-30

62 Corticosterone as a potential confounding factor in delineating mechanisms underlying ketamine's rapid antidepressant actions

Wegman-Points, L.; Pope, B.; Zobel, A.; Semke, L.; Wauson, E.; Duric, V.; Yuan, L.-L.

10.1101/2019.12.30.891333 — neuroscience — Posted on 2019-12-30

63 Comparative proteomics of octocoral and scleractinian skeletomes and the evolution of coral calcification

Conci, N.; Lehmann, M.; Vargas, S.; Woerheide, G.

10.1101/2019.12.30.891028 — evolutionary biology — Posted on 2019-12-30

64 Global redistribution and local migration in semi-discrete host-parasitoid population dynamic models.

Emerick, B. K.; Singh, A. K.

10.1101/2019.12.30.891044 — ecology — Posted on 2019-12-30

65 Large-scale nuclear remodeling and transcriptional deregulation occur on both derivative chromosomes after Mantle cell lymphoma chromosomal translocation

Sall, F. B.; Pichugin, A.; Iarovaia, O.; Barat, A.; Tsfasman, T.; Brossas, C.; Prioleau, M.-N.; Lazarovici, J.; Camara-Clayette, V.; Ribrag, V.; Lipinski, M.; Vassetzky, Y.; Germini, D.

10.1101/2019.12.30.882407 — cancer biology — Posted on 2019-12-30

66 Capturing multiple timescales of adaptation to second-order statistics with generalized linear models: gain scaling and fractional differentiation

Latimer, K. W.; Fairhall, A. L.

10.1101/2019.12.30.891143 — neuroscience — Posted on 2019-12-30

67 Neonatal granulocytic MDSCs possess phagocytic properties during bacterial infection.

Seman, B. G.; Vance, J. K.; Witt, M. R.; Robinson, C. M.

10.1101/2019.12.30.891077 — immunology — Posted on 2019-12-30

68 Induction of Recurrent Break Cluster Genes in Neural Progenitor Cells Differentiated from Embryonic Stem Cells In Culture

Tena, A.; Zhang, Y.; Kyritsis, N.; Devorak, A.; Zurita, J.; Wei, P.-C.; Alt, F. W.

10.1101/2019.12.30.891168 — neuroscience — Posted on 2019-12-30

69 Kirrel3-mediated synapse formation is attenuated by disease-associated missense variants

Taylor, M. R.; Martin, E. A.; Sinnen, B.; Trilokekar, R.; Ranza, E.; Antonarakis, S. E.; Williams, M. E.

10.1101/2019.12.30.891085 — neuroscience — Posted on 2019-12-30

70 A standardized gnotobiotic mouse model harboring a minimal 15-member mouse gut microbiota recapitulates SOPF phenotype

Darnaud, M.; De Vadder, F.; Bogeat, P.; Boucinha, L.; Bulteau, A.-L.; Bunescu, A.; Chaix, J.; Couturier, C.; Delgado, A.; Dugua, H.; Elie, C.; Mathieu, A.; Ouattara, D. A.; Planel, S.; Saliou, A.; Yansouni, J.; Schwarzer, M.; Leulier, F.; Tamellini, A.

10.1101/2019.12.30.890954 — microbiology — Posted on 2019-12-30

71 Influenza H3 and H1 hemagglutinins have different genetic barriers for resistance to broadly neutralizing stem antibodies

Wu, N. C.; Thompson, A. J.; Lee, J. M.; Su, W.; Arlian, B. M.; Xie, J.; Lerner, R. A.; Yen, H.-L.; Bloom, J. D.; Wilson, I. A.

10.1101/2019.12.30.891135 — microbiology — Posted on 2019-12-30

72 Single Cell Profiling of Acute Kidney Injury Reveals Novel Transcriptional Signatures, Mixed Identities and Epithelial-to-Stromal Crosstalk

Rudman-Melnick, V.; Adam, M.; Potter, A.; Chokshi, S. M.; Ma, Q.; Drake, K.; Schuh, M. P.; Kofron, J. M.; Devarajan, P.; Potter, S. S.

10.1101/2019.12.30.890905 — developmental biology — Posted on 2019-12-30

73 Alternating regimes of motion in cell motility models

Guisoni, N.; Mazzitello, K. I.; Diambra, L.

10.1101/2019.12.30.891093 — biophysics — Posted on 2019-12-30

74 Altered active control of step width in response to mediolateral leg perturbations while walking

Reimold, N. K.; Knapp, H. A.; Henderson, R. E.; Wilson, L.; Chesnutt, A. N.; Dean, J. C.

10.1101/2019.12.30.890947 — bioengineering — Posted on 2019-12-30

75 Targeting the Pregnane X Receptor Using Microbial Metabolite Mimicry

Dvorak, Z.; Felix Kopp, F.; Costello, C. M.; Kemp, J. S.; Li, H.; Vrzalova, A.; Stepankova, M.; Iveta Bartonkov, I.; Poulikova, K.; Vyhlidalova, B.; Nordstroem, L. U.; Karunaratne, C.; Ranhotra, H.; Mun, K. S.; Naren, A. P.; Murray, I.; Perdew, G. H.; Brtko, J.; Toporova, L.; Schon, A.; Wallace, B.; Walton, W. G.; Redinbo, M. R.; Sun, K.; Beck, A.; Kortagere, S.; Neary, M. C.; Chandran, A.; Vishveshwara, S.; Cavalluzzi, M. M.; Lentini, G.; Cui, J. Y.; Gu, H.; March, J. C.; Chaterjee, S.; Matson, A.; Wright, D.; Flannigan, K. L.; Hirota, S. A.; Mani, S.; Sartor, R. B.

10.1101/792671 — biochemistry — Posted on 2019-12-30

76 Two roles for the yeast transcription coactivator SAGA and a set of genes redundantly regulated by TFIID and SAGA

Donczew, R.; Warfield, L.; Pacheco, D.; Erijman, A.; Hahn, S.

10.1101/745059 — molecular biology — Posted on 2019-12-30

77 A subset of broadly responsive Type III taste cells contribute to the detection of bitter, sweet and umami stimuli

Dutta Banik, D.; Benfey, E. D.; Martin, L. E.; Kay, K. E.; Loney, G. C.; Nelson, A. R.; Ahart, Z. C.; Kemp, B. T.; Kemp, B. R.; Torregrossa, A.-M.; Medler, K. F.

10.1101/660589 — neuroscience — Posted on 2019-12-30

78 Phloem-mediated spreading of SIGS-derived non-coding RNAs in Hordeum vulgare

Biedenkopf, D.; Will, T.; Knauer, T.; Jelonek, L.; Furch, A. C. U.; Busche, T.; Koch, A.

10.1101/2019.12.30.891002 — plant biology — Posted on 2019-12-30

79 Xenotransplantation of Human PSC-derived Microglia Creates a Chimeric Mouse Brain Model that Recapitulates Features of Adult Human Microglia

Xu, R.; Boreland, A.; Li, X.; Posyton, A.; Kwan, K.; Hart, R. P.; Jiang, P.

10.1101/594721 — neuroscience — Posted on 2019-12-30

80 The Spectral Sensitivity of the Neurons Mediating Black and White

Patterson, S. S.; Neitz, M.; Neitz, J.

10.1101/829051 — neuroscience — Posted on 2019-12-30

81 Opponent regulation of action performance and timing by striatonigral and striatopallidal pathways

Bakhurin, K. I.; Li, X.; Friedman, A. D.; Lusk, N. A.; Watson, G. D.; Kim, N.; Yin, H. H.

10.1101/2019.12.26.889030 — neuroscience — Posted on 2019-12-30

82 Adaption of a Conventional ELISA to a 96-well ELISA-Array for Measuring the Antibody Responses to Influenza virus proteins, viruses and vaccines

Waltari, E.; Carabajal, E.; Sanyal, M.; Friedland, N.; McCutcheon, K. M.

10.1101/2019.12.20.885285 — immunology — Posted on 2019-12-30

83 The co-stimulatory activity of Tim-3 requires Akt and MAPK signaling and immune synapse recruitment

Kataoka, S.; Manandhar, P.; Workman, C. J.; Banerjee, H.; Szymczak-Workman, A. L.; Kvorjak, M.; Lohmueller, J.; Kane, L. P.

10.1101/2019.12.30.878520 — immunology — Posted on 2019-12-30

84 Involvement of orexin/hypocretin in the expression of social play behaviour in juvenile rats

Reppucci, C. J.; Gergely, C. K.; Bredewold, R.; Veenema, A. H.

10.1101/809475 — neuroscience — Posted on 2019-12-30

85 A single-cell survey of Drosophila blood

Tattikota, S. G.; Hu, Y.; Liu, Y.; Cho, B.; Barrera, V.; Steinbaugh, M.; Yoon, S.-H.; Comjean, A.; Li, F.; Dervis, F.; Hung, R.-J.; Nam, J.-W.; Ho Sui, S.; Shim, J.; Perrimon, N.

10.1101/2019.12.20.884999 — immunology — Posted on 2019-12-30

86 Selective sweeps in a nutshell; the genomic footprint of rapid insecticide resistance evolution in a major insect pest of tree nuts

Calla, B.; Demkovich, M. R.; Siegel, J. P.; Gomes Viana, J. P.; Walden, K. K. O.; Robertson, H. M.; Berenbaum, M. R.

10.1101/828418 — genomics — Posted on 2019-12-30

87 DRB1 as a mediator between transcription and microRNA processing

Bielewicz, D.; Dolata, J.; Bajczyk, M.; Szewc, L.; Gulanicz, T.; Bhat, S. S.; Karlik, A.; Jarmolowski, A.; Szweykowska-Kulinska, Z.

10.1101/2019.12.30.890665 — plant biology — Posted on 2019-12-30

88 Anti-inflammatory properties of chemical probes in human whole blood: focus on prostaglandin E2 production

Bergqvist, F.; Sundström, Y.; Shang, M.; Gunnarsson, I.; Lundberg, I.; Sundström, M.; Jakobsson, P.-J.; Berg, L.

10.1101/2019.12.30.890715 — immunology — Posted on 2019-12-30

89 RhoC modulates metabolic networks in cervical cancer by transcriptionally regulating the expression of genes involved in metabolism

Thomas, P.; Bhavani, C.; Srivastava, S.

10.1101/2019.12.29.890640 — cancer biology — Posted on 2019-12-30

90 Single-Cell Map of Diverse Immune Phenotypes in the Metastatic Brain Tumor Microenvironment of Non Small Cell Lung Cancer

Wang, L.; Dai, J.; Han, R.-R.; Dong, L.; Feng, D.; Zhu, G.; Guo, W.; Wang, Y.; Chao, M.; Jin, M.-Z.; Jin, S.-J.; Wei, D.-P.; Sun, W.; Jin, W.-L.

10.1101/2019.12.30.890517 — cancer biology — Posted on 2019-12-30

91 Protein-free division of giant unilamellar vesicles controlled by enzymatic activity

Dreher, Y.; Spatz, J. P.; Göpfrich, K.

10.1101/2019.12.30.881557 — biophysics — Posted on 2019-12-30

92 Genotype Effects and Gene x Environment Interactions on Inter-Individual Licking Received and Licking Provisioning in Female Rat Offspring

Lauby, S. C.; Ashbrook, D. G.; Malik, H. R.; Chatterjee, D.; Pan, P.; Fleming, A. S.; McGowan, P. O.

10.1101/2019.12.29.890467 — neuroscience — Posted on 2019-12-30

93 The Cryo-EM Structure of a Pannexin 1 Channel Reveals an Extracellular Gating Mechanism

Michalski, K.; Syrjanen, J. L.; Henze, E.; Kumpf, J.; Furukawa, H.; Kawate, T.

10.1101/2019.12.30.890780 — neuroscience — Posted on 2019-12-30

94 Polar pattern formation induced by contact following locomotion in a multicellular system

Hayakawa, M.; Hiraiwa, T.; Wada, Y.; Kuwayama, H.; Shibata, T.

10.1101/2019.12.29.890566 — biophysics — Posted on 2019-12-30

95 Structural basis for pore blockade of the human cardiac sodium channel Nav1.5 by tetrodotoxin and quinidine

Yan, N.; Li, Z.; Jin, X.; Huang, G.; Wu, K.; Lei, J.; Pan, X.

10.1101/2019.12.30.890681 — biophysics — Posted on 2019-12-30

96 Vulnerability correlates with life history traits and the load of deleterious mutations in fish.

Rolland, J.; Romiguier, J.

10.1101/2019.12.29.890038 — molecular biology — Posted on 2019-12-30

97 Increased calcidiol level in redhaired people: Could redheadedness be an adaptation to temperate climate?

Flegr, J.; Sykorova, K.; Fiala, V.; Hlavacova, J.; Bicikova, M.; Macova, L.; Kankova, S.

10.1101/2019.12.30.890889 — evolutionary biology — Posted on 2019-12-30

98 FGFR/Heartless and Smog interact synergistically to negatively regulate Fog mediated GPCR signaling.

Shweta, K.; Basargekar, A. S.; Ratnaparkhi, A.

10.1101/2019.12.30.890871 — cell biology — Posted on 2019-12-30

99 Microgravity modulates effects of chemotherapeutic drugs on cancer cell migration

Prasanth, D.; Suresh, S.; Prathivadhi-Bhayankaram, S. V.; Mimlitz, M.; Zetocha, N.; Lee, B.; Ekpenyong, A. E.

10.1101/2019.12.29.890632 — biophysics — Posted on 2019-12-30

100 Calcium induced calcium release in proximity to hair cell BK channels revealed by PKA activation

Bai, J.; Xue, N.; Lawal, O.; Nyati, A.; Santos-Sacchi, J.; Navaratnam, D. S.

10.1101/2019.12.30.890558 — physiology — Posted on 2019-12-30

101 Dexmedetomidine - commonly used in resting-state and neurovascular coupling studies - is prone to inducing seizures in rats but not in wild type mice

Bortel, A.; Yao, Z. S.; Shmuel, A.

10.1101/2019.12.29.890525 — neuroscience — Posted on 2019-12-30

102 Mitochondrial Proteome of Affected Neurons in a Mouse Model of Leigh Syndrome

Gella, A.; Prada Dacasa, P.; Carrascal, M.; Gonzalez Torres, M.; Abian, J.; Sanz, E.; Quintana, A.

10.1101/2019.12.29.890541 — neuroscience — Posted on 2019-12-30

103 Predictive olfactory learning in Drosophila

Zhao, C.; Widmer, Y.; Diegelmann, S.; Petrovici, M.; Sprecher, S.; Senn, W.

10.1101/2019.12.29.890533 — neuroscience — Posted on 2019-12-30

104 Learning temporal integration from internal feedback

Nygren, E.; Ramirez, A.; McMahan, B.; Aksay, E.; Senn, W.

10.1101/2019.12.29.890509 — neuroscience — Posted on 2019-12-30

105 Tracking niche change through time: simultaneous inference of environmental niche evolution and estimation of contemporary niches

Hua, X.; Cardillo, M.; Bromham, L.

10.1101/2019.12.29.890608 — evolutionary biology — Posted on 2019-12-30

106 Leader cell activity and collective invasion by an autocrine nucleotide loop through connexin-43 hemichannels and ADORA1

Khalil, A. A.; Ilina, O.; Vasaturo, A.; Venhuizen, J.-H.; Vullings, M.; Venhuizen, V.; Bilos, A.; Figdor, C.; Span, P. N.; Friedl, P.

10.1101/2019.12.30.888958 — cancer biology — Posted on 2019-12-30

107 Gold nanorod based delivery system could bring about superior therapy effect of Ramucirumab through direct cytotoxicity to cancer cell mediated by differential regulation of phagocytosis in gastric cancer cell

Fan, L.; Zhao, M.

10.1101/2019.12.29.888537 — bioengineering — Posted on 2019-12-30

108 Dual role of auxin in regulating plant defense and bacterial virulence gene expression during Pseudomonas syringae PtoDC3000 pathogenesis.

Djami-Tchatchou, A. T.; Harrison, G. A.; Harper, C. P.; Wang, R.; Prigge, M. J.; Estelle, M.; Kunkel, B. N.

10.1101/2019.12.29.881581 — plant biology — Posted on 2019-12-30

109 An antibody drug conjugate targeting a GSTA glycosite-signature epitope of mucin1 expressed by non-small cell lung cancer

Pan, D.; Tang, Y.; Tong, J.; Xie, C.; Chen, J.; Feng, C.; Hwu, P.; Huang, W.; Zhou, D.

10.1101/2019.12.22.885566 — pharmacology and toxicology — Posted on 2019-12-30

110 Megakaryocytes, erythropoietic and granulopoietic cells express CAL2 antibody in myeloproliferative neoplasms carrying CALR gene mutations

Ali, H.; Puccio, I.; Akarca, A.; Bob, R.; Pomplun, S.; Wong, W. K.; Gupta, R.; Sekhar, M.; Lambert, J.; Al-Masri, H.; Stein, H.; Marafioti, T.

10.1101/2019.12.22.886317 — pathology — Posted on 2019-12-30

111 Pragmatic spatial sampling for wearable MEG arrays

Tierney, T. M.; Mellor, S.; O'Neil, G. C.; Holmes, N.; Boto, E.; Roberts, G.; Hill, R. M.; Legget, J.; Bowtell, R.; Brookes, M. J.; Barnes, G. R.

10.1101/2019.12.29.890426 — neuroscience — Posted on 2019-12-30

112 Conglomeration of highly antigenic nucleoproteins to inaugurate a heterosubtypic next generation vaccine candidate against Arenaviridae family

Azim, K. F.; Lasker, T.; Akter, R.; Hia, M. M.; Bhuiyan, O. F.; Hasan, M.; Hossain, M. N.

10.1101/2019.12.29.885731 — bioinformatics — Posted on 2019-12-30

113 Graded recruitment of pupil-linked neuromodulation by parametric stimulation of the vagus nerve

Mridha, Z.; de Gee, J. W.; Shi, Y.; Alkashgari, R.; Williams, J.; Suminski, A.; Ward, M. P.; Zhang, W.; McGinley, M. J.

10.1101/2019.12.28.890111 — neuroscience — Posted on 2019-12-30

114 Efficient data management infrastructure for the integration of imaging and omics data in life science research

Kuhn Cuellar, L.; Friedrich, A.; Gabernet, G.; de la Garza, L.; Fillinger, S.; Seyboldt, A.; zur Oven-Krockhaus, S.; Wanke, F.; Richter, S.; Thaiss, W. M.; Horger, M.; Malek, N.; Harter, K.; Bitzer, M.; Nahnsen, S.

10.1101/2019.12.28.889295 — bioinformatics — Posted on 2019-12-30

115 Empirical decomposition of the explained variation in the variance components form of the mixed model

Schreck, N.

10.1101/2019.12.28.890061 — genomics — Posted on 2019-12-30

116 Quantifying the dynamics of pig movements improve targeted disease surveillance and control plans

Machado, G.; Galvis, J. A.; Lopes, F. P. N.; Voges, J.; Medeiros, A. A. R.; Cardenas, N.

10.1101/2019.12.29.886408 — ecology — Posted on 2019-12-30

117 NanoCaller for accurate detection of SNPs and small indels from long-read sequencing by deep neural networks

Ahsan, U.; Liu, Q.; Wang, K.

10.1101/2019.12.29.890418 — bioinformatics — Posted on 2019-12-30

118 Human walking in the real world: Interactions between terrain type, gait parameters, and energy expenditure

Kowalsky, D. B.; Rebula, J. R.; Ojeda, L. V.; Adamczyk, P. G.; Kuo, A. D.

10.1101/2019.12.29.890434 — bioengineering — Posted on 2019-12-30

119 Aquaculture potential of Bohai Red and its hybrid with Agropecten irradians concentricus in southern China

yao, g.; li, j.; su, x.; Liu, z.

10.1101/2019.12.29.890160 — zoology — Posted on 2019-12-30

120 When to wake up? The optimal waking-up strategies for starvation-induced persistence

Himeoka, Y.; Mitarai, N.

10.1101/2019.12.29.890285 — systems biology — Posted on 2019-12-30

121 The Ocular Glymphatic Clearance System

Wang, X.; Lou, N.; Eberhardt, A.; Kusk, P.; Xu, Q.; Forstera, B.; Peng, S.; Yang, Y.; Shi, M.; Xavier, A. L. R.; Erturk, A.; Libby, R. T.; Chen, L.; Thrane, A. S.; Nedergaard, M.

10.1101/2019.12.29.889873 — physiology — Posted on 2019-12-30

122 Graded, multi dimensional intragroup and intergroup variations in primary progressive aphasia and post stroke aphasia.

Ingram, R. U.; Halai, A. D.; Pobric, G.; Sajjadi, S. A.; Patterson, K.; Lambon Ralph, M. A.

10.1101/2019.12.29.882068 — neuroscience — Posted on 2019-12-30

123 Disrupted neural synchrony mediates the relationship between white matter integrity and cognitive performance in older adults.

Hinault, T. T.; Kraut, M.; Bakker, A.; Dagher, A.; Courtney, S.

10.1101/2019.12.29.890228 — neuroscience — Posted on 2019-12-30

124 The history of measles: from a 1912 genome to an antique origin

Duex, A.; Lequime, S.; Patrono, L. V.; Vrancken, B.; Boral, S.; Gogarten, J. F.; Hilbig, A.; Horst, D.; Merkel, K.; Prepoint, B.; Santibanez, S.; Schlotterbeck, J.; Suchard, M. A.; Ulrich, M.; Widulin, N.; Mankertz, A.; Leendertz, F. H.; Harper, K.; Lemey, P.; Calvignac-Spencer, S.

10.1101/2019.12.29.889667 — evolutionary biology — Posted on 2019-12-30

125 Epimutations driven by small RNAs arise frequently but have limited duration in a metazoan organism

Beltran, T.; Shahrezaei, V.; Katju, V.; Sarkies, P.

10.1101/2019.12.29.890194 — genetics — Posted on 2019-12-30

126 Explainable Deep Relational Networks for Predicting Compound-Protein Affinities and Contacts

Karimi, M.; Wu, D.; Wang, Z.; Shen, Y.

10.1101/2019.12.28.890103 — bioinformatics — Posted on 2019-12-30

127 Reliable readout of mixture components from small populations of piriform cortical neurons

Penker, S.; Licht, T.; Rokni, D.

10.1101/2019.12.26.888693 — neuroscience — Posted on 2019-12-30

128 Spontaneous and automatic processing of magnitude and parity information of Arabic digits: A frequency-tagging EEG study.

Guillaume, M.; Poncin, A.; Schiltz, C.; Van Rinsveld, A.

10.1101/2019.12.26.888651 — neuroscience — Posted on 2019-12-30

129 Identifying differential cell populations in flow cytometry data accounting for marker frequency

Yue, A.; Chauve, C.; Libbrecht, M.; Brinkman, R.

10.1101/837765 — bioinformatics — Posted on 2019-12-30

130 Presynaptic developmental plasticity allows robust sparse wiring of the Drosophila mushroom body

Elkahlah, N. A.; Rogow, J. A.; Ahmed, M.; Clowney, E. J.

10.1101/782961 — neuroscience — Posted on 2019-12-30

131 A flexible pipeline combining clustering and correction tools for prokaryotic and eukaryotic metabarcoding

Brandt, M. I.; Trouche, B.; Quintric, L.; Wincker, P.; Poulain, J.; Arnaud-Haond, S.

10.1101/717355 — bioinformatics — Posted on 2019-12-30

132 Systematic assessment of tissue dissociation and storage biases in single-cell and single-nucleus RNA-seq workflows

Denisenko, E.; Guo, B. B.; Jones, M.; Hou, R.; de Kock, L.; Lassmann, T.; Poppe, D.; Clement, O.; Simmons, R. K.; Lister, R.; Forrest, A. R. R.

10.1101/832444 — genomics — Posted on 2019-12-30

133 High-resolution synchrotron imaging studies of intact fresh roots reveal soil bacteria promoted bioremediation and bio-fortification

Help, H.; Lusa, M.; Honkanen, A.-P.; Diaz, A.; Holler, M.; Salome, M.; Cloetens, P.; Makinen, H.; Huotari, S.; Suhonen, H.

10.1101/767558 — plant biology — Posted on 2019-12-30

134 Effect of Exogenous Amino Acids on Yield and Quality of Tartary Buckwheat in Non-saline and Saline-alkali Soil

Song, J.-N.; Wang, Y.-Q.; Li, S.; Li, F.-L.; Hu, Y.-J.; Yang, H.-B.

10.1101/2019.12.24.887778 — physiology — Posted on 2019-12-30

135 Quantitative trait loci (QTL) underlying phenotypic variation in bioethanol-related processes in Neurospora crassa.

Waters, J. C.; Jhaveri, D.; Biffinger, J. C.; Lee, K.

10.1101/736470 — microbiology — Posted on 2019-12-30

136 The open bar is closed: restructuration of a native parasitoid community following successful control of an invasive pest.

Muru, D.; Borowiec, N.; Thaon, M.; Ris, N.; Vercken, E.

10.1101/2019.12.20.884908 — ecology — Posted on 2019-12-30

137 The differentiation commitment point closes a proliferative window that controls the total number of terminally differentiated cells

Zhao, M. L.; Rabiee, A.; Kovary, K. M.; Bahrami-Nejad, Z.; Taylor, B.; Teruel, M. N.

10.1101/632570 — cell biology — Posted on 2019-12-30

138 Genomic adaptations to aquatic and aerial life in mayflies and the origin of wings in insects

Almudi, I.; Vizueta, J.; de Mendoza, A.; Wyatt, C.; Marletaz, F.; Firbas, P.; Feuda, R.; Masiero, G.; Medina, P.; Alcaina, A.; Cruz, F.; Gomez-Garrido, J.; Gut, M.; Alioto, T. S.; Vargas-Chavez, C.; Davie, K.; Misof, B.; Gonzalez, J.; Aerts, S.; Lister, R.; Paps, J.; Rozas, J.; Sanchez-Gracia, A.; Irimia, M.; Maeso, I.; Casares, F.

10.1101/2019.12.29.888636 — evolutionary biology — Posted on 2019-12-30

139 Olfactory receptors tuned to volatile mustard oils in drosophilid flies

Matsunaga, T.; Reisenman, C. E.; Goldman-Huertas, B.; Brand, P.; Miao, K.; Suzuki, H.; Ramirez, S. R.; Whiteman, N. K.

10.1101/2019.12.27.889774 — evolutionary biology — Posted on 2019-12-30

140 Physicochemical changes in plasma membrane mirror nanoparticle-mediated cytotoxicity

Sood, V.; Katti, D. S.

10.1101/2019.12.29.890236 — bioengineering — Posted on 2019-12-30

141 Subcellular protein profiling with far-red light mediated proximal labeling

Li, Z.

10.1101/2019.12.28.890095 — biochemistry — Posted on 2019-12-30

142 Hydroxide Ion Carrier for Proton Pump in Bacteriorhodopsin: Primary Proton Transfer

Imai, M.; Ono, J.; Nishimura, Y.; Nakai, H.

10.1101/2019.12.23.887216 — biophysics — Posted on 2019-12-30

143 Highly heterogeneous long-range interactions explain chromosome compartmentalization

Eidelman, Y. A.; Salnikov, I. V.; Slanina, S. V.; Andreev, S.

10.1101/2019.12.29.890459 — biophysics — Posted on 2019-12-30

144 Hox binding specificity is directed by DNA sequence preferences and differential abilities to engage inaccessible chromatin.

Bulajic, M.; Srivastava, D.; Dasen, J.; Wichterle, H.; Mahony, S.; Mazzoni, E. O.

10.1101/2019.12.29.890335 — developmental biology — Posted on 2019-12-30

145 Collaborative Behavior of Urea and KI in Denaturing Protein Native Structure

Shao, Q.; Wang, J.; Zhu, W.

10.1101/2019.12.29.888271 — biophysics — Posted on 2019-12-30

146 CAP-MAP: Cap Analysis Protocol with Minimal Analyte Processing, a rapid and sensitive approach to analysing mRNA cap structures

Galloway, A.; Atrih, A.; Grzela, R.; Darzynkiewicz, E.; Ferguson, M. A.; Cowling, V. H.

10.1101/2019.12.29.890368 — biochemistry — Posted on 2019-12-30

147 Olfactory receptors tuned to volatile mustard oils in drosophilid flies

Matsunaga, T.; Reisenman, C. E.; Goldman-Huertas, B.; Brand, P.; Miao, K.; Suzuki, H.; Ramirez, S. R.; Whiteman, N. K.

10.1101/2019.12.27.889774 — evolutionary biology — Posted on 2019-12-29

148 Amyloid-like aggregates cause lysosomal defects in neurons via gain-of-function toxicity

Schaefer, T.; Riera-Tur, I.; Hornburg, D.; Mishra, A.; Fernandez-Mosquera, L.; Raimundo, N.; Mann, M.; Baumeister, W.; Klein, R.; Meissner, F.; Fernandez-Busnadiego, R.; Dudanova, I.

10.1101/2019.12.16.877431 — cell biology — Posted on 2019-12-29

149 Partial loss of colonic primary cilia promotes inflammation and carcinogenesis

Tang, R.; Paul, C.; Lattanzio, R.; Eguether, T.; Tulari, H.; Bremond, J.; Maurizy, C.; Poupeau, S.; Turtoi, A.; Svrcek, M.; Seksik, P.; Castronovo, V.; Delvenne, P.; Lemmers, B.; Janke, C.; Pinet, V.; Hahne, M.

10.1101/2019.12.20.871772 — cancer biology — Posted on 2019-12-29

150 Relationship between neural phase-locked responses to speech and perception of speech in noise in young and older adults

Mai, G.; Howell, P.

10.1101/794313 — neuroscience — Posted on 2019-12-29

151 Functional Vagotopy in the Cervical Vagus Nerve of the Domestic Pig: Implications for the Study of Vagus Nerve Stimulation

Settell, M. L.; Knudsen, B. E.; Dingle, A. M.; McConico, A. L.; Nicolai, E. N.; Trevathan, J. K.; Ross, E. K.; Pelot, N. A.; Grill, W. M.; Gustafson, K. J.; Shoffstall, A. J.; Williams, J. C.; Zeng, W.; Poore, S. O.; Populin, L. C.; Suminski, A. J.; Ludwig, K. A.

10.1101/856989 — neuroscience — Posted on 2019-12-29

152 Large-Scale Survey of Cell-Differentiation Programs in a Generative Model Reveals Regeneration as an Epiphenomenon of Development

Mani, S.; Tlusty, T.

10.1101/843888 — developmental biology — Posted on 2019-12-29

153 Collective interactions augment influenza A virus replication in a host-dependent manner

Phipps, K. L.; Ganti, K.; Jacobs, N. T.; Lee, C.-Y.; Carnacinni, S.; White, M. C.; Manandhar, M.; Pickett, B. E.; Tan, G. S.; Ferreri, L. M.; Perez, D. R.; Lowen, A. C.

10.1101/736108 — microbiology — Posted on 2019-12-29

154 Does Vision Extract Absolute Distance From Vergence?

Linton, P.

10.1101/731109 — neuroscience — Posted on 2019-12-29

155 EZH2 inhibition results in genome-wide PRC2 redistribution

Yuan, C.-C.; Jeon, A.-J.; Tucker-Kellogg, G.; Bryant, B.; Trojer, P.

10.1101/713842 — genomics — Posted on 2019-12-29

156 Vineyard ecosystems are structured and distinguished by fungal communities impacting the flavour and quality of wine

Liu, D.; Chen, Q.; Zhang, P.; Chen, D.; Howell, K.

10.1101/2019.12.27.881656 — microbiology — Posted on 2019-12-29

157 Bayesian inference of the gene expression states of single cells from scRNA-seq data

Breda, J.; Zavolan, M.; van Nimwegen, E. J.

10.1101/2019.12.28.889956 — bioinformatics — Posted on 2019-12-29

158 NDRG2 Regulates Adherens Junction Integrity to Restrict Colitis and Tumorigenesis

Wei, m.; Ma, Y.; Shen, l.; Xu, Y.; Liu, L.; Bu, X.; Guo, Z.; Qin, H.; Li, Z.; Wang, Z.; Wu, K.; Yao, L.; Li, J.; zhang, j.

10.1101/473397 — cancer biology — Posted on 2019-12-29

159 Quantitative Structure-Mutation-Activity Relationship Tests (QSMART) Model for Protein Kinase Inhibitor Response Prediction

Huang, L.-C.; Yeung, W.; Wang, Y.; Cheng, H.; Venkat, A.; Li, S.; Ma, P.; Rasheed, K.; Kannan, N.

10.1101/868067 — bioinformatics — Posted on 2019-12-29

160 Design to Data for mutants of β-glucosidase B from Paenibacillus polymyxa: Q22T, W123R, F155G, Y169M, W438D, V401A

Hou, C.; Smith, P.; Huang, J.; Fell, J. S.; Huang, P.; Vater, A.; Siegel, J. B.

10.1101/2019.12.23.887380 — biochemistry — Posted on 2019-12-29

161 Membrane insertion of chromogranin B for granule maturation in regulated secretion

Yadav, G.; Wang, H.; Ouwendijk, J.; Annamalai, M.; Cross, S.; Wang, Q.; Hagan, D. W.; Mathews, C.; Phelps, E.; Verkade, P.; Zhu, M. X.; Jiang, Q.-X.

10.1101/2019.12.28.890053 — cell biology — Posted on 2019-12-29

162 A Molecular Pathway for Arterial-Specific Association of Vascular Smooth Muscle Cells

Stratman, A. N.; Burns, M. C.; Farrelly, O. M.; Davis, A. E.; Li, W.; Pham, V. N.; Castranova, D.; Yano, J. J.; Goddard, L. M.; Nguyen, O.; Venero Galanternik, M.; Bolan, T. J.; Kahn, M. L.; Mukouyama, Y.; Weinstein, B. M.

10.1101/2019.12.27.889782 — cell biology — Posted on 2019-12-28

163 Introducing divisive inhibition in the Wilson-Cowan model

Papasavvas, C. A.; Wang, Y.

10.1101/2019.12.27.889642 — neuroscience — Posted on 2019-12-28

164 Computations, optimization and tuning of deep feedforward neural networks

Rahman, M. S.

10.1101/2019.12.27.889311 — neuroscience — Posted on 2019-12-28

165 An ultrasound absorbing inflorescence zone enhances echo-acoustic contrast of bat-pollinated cactus flowers

Simon, R.; Matt, F.; Santillan, V.; Tschapka, M.; Tuttle, M.; Halfwerk, W.

10.1101/2019.12.28.890046 — ecology — Posted on 2019-12-28

166 Deep6mA: a deep learning framework for exploring similar patterns in DNA N6-methyladenine sites across different species

Pian, C.; Li, Z.; Jiang, H.; Kong, L.; Chen, Y.; Zhang, L.

10.1101/2019.12.28.889824 — bioinformatics — Posted on 2019-12-28

167 Reliable readout of mixture components from small populations of piriform cortical neurons

Penker, S.; Licht, T.; Rokni, D.

10.1101/2019.12.26.888693 — neuroscience — Posted on 2019-12-28

168 An Unconventional Melanin Biosynthetic Pathway in Ustilago maydis

Reyes-Fernandez, E. Z.; Shi, Y.-M.; Grün, P.; Bode, H. B.; Bölker, M.

10.1101/2019.12.28.889758 — genetics — Posted on 2019-12-28

169 Cancer causes metabolic perturbations associated with reduced insulin-stimulated glucose uptake in peripheral tissues and impaired muscle microvascular perfusion

Han, X.; Raun, S.; Carlsson, M.; Sjoberg, K. A.; Henriquez-Olguin, C.; Ali, M.; Lundsgaard, A.; Fritzen, A. M.; Moller, L. L. V.; Li, Z.; Li, J.; Jensen, T. E.; Kiens, B.; Sylow, L.

10.1101/734764 — cancer biology — Posted on 2019-12-28

170 Major QTLs for seedling traits in barley using a DArT-based linkage map

Capo-chich, L.; Eldridge, S.; Elakhdar, A.; Kumamaru, T.; Anyia, A.

10.1101/2019.12.28.889899 — plant biology — Posted on 2019-12-28

171 Prolonged reaction times eliminate residual errors in visuomotor adaptation

Langsdorf, L.; Maresch, J.; Hegele, M.; McDougle, S. D.; Schween, R.

10.1101/2019.12.26.888941 — neuroscience — Posted on 2019-12-28

172 UP{varphi} phages, a new group of filamentous phages found in several members of Enterobacteriales

Shapiro, J. W.; Putonti, C.

10.1101/2019.12.27.889675 — microbiology — Posted on 2019-12-28

173 Discovery of new mitochondrial DNA segregation machinery components in Trypanosoma brucei: a comparison of three approaches

Baudouin, H. C. M.; Pfeiffer, L.; Ochsenreiter, T.

10.1101/2019.12.28.889931 — cell biology — Posted on 2019-12-28

174 Dynamics of diffusive cell signaling relays

Dieterle, P.; Min, J.; Irimia, D.; Amir, A.

10.1101/2019.12.27.887273 — biophysics — Posted on 2019-12-28

175 Quantitative Measurements Of Hydroxyl Radicals Generated By Irradiated Titanium Dioxide Nanoparticle Suspensions

Coral, J. A.; Kitchens, C. L.

10.1101/2019.12.27.889618 — ecology — Posted on 2019-12-28

176 Private information leakage from functional genomics data: Quantification with calibration experiments and reduction via data sanitization protocols

Gursoy, G.; Emani, P. S.; Jolanki, O. A.; Brannon, C.; Harmanci, A. O.; Strattan, J. S.; Miranker, A. D.; Gerstein, M.

10.1101/345074 — bioinformatics — Posted on 2019-12-28

177 Characterization of human iPSC-derived astrocytes with potential for disease modeling and drug discovery

Soubannier, V.; Maussion, G.; Chaineau, M.; Sigutova, V.; Rouleau, G.; Durcan, T.; Stifani, S.

10.1101/2019.12.28.890012 — neuroscience — Posted on 2019-12-28

178 Benzaldehyde Synthases Are Encoded by Cinnamoyl-CoA Reductase Genes in Cucumber (Cucumis sativus L.)

Liu, B.; Wei, G.; Hu, Z.; Wang, G.

10.1101/2019.12.26.889071 — biochemistry — Posted on 2019-12-28

179 Learning to find the center of symmetric and asymmetric spatial layouts by the house cricket, Acheta domesticus

Baran, B.; Krzyzowski, M.; Radai, Z.; Francikowski, J.; Hohol, M.

10.1101/2019.12.28.886655 — animal behavior and cognition — Posted on 2019-12-28

180 Mapping biology from mouse to man using transfer learning

Stumpf, P. S.; Du, D.; Imanishi, H.; Kunisaki, Y.; Semba, Y.; Noble, T.; Smith, R. C.; Rose-Zerili, M.; West, J. J.; Oreffo, R. O.; Niranjan, M.; Akashi, K.; Arai, F.; MacArthur, B. D.

10.1101/2019.12.26.888842 — systems biology — Posted on 2019-12-28

181 DNA methylation across the genome in aged human skeletal muscle tissue and muscle stem cells: The role of HOX genes and physical activity

Turner, D. C.; Gorski, P. P.; Maasar, M. F.; Seaborne, R. A.; Baumert, P.; Brown, A. D.; Kitchen, M. O.; Erskine, R. M.; Dos-Remedios, I.; Voisin, S.; Eynon, N.; Sultanov, R. I.; Borisov, O. V.; Larin, A. K.; Semenova, E. A.; Popov, D. V.; Generozov, E. V.; Stewart, C. E.; Drust, B.; Owens, D. J.; Ahmetov, I. I.; Sharples, A. P.

10.1101/2019.12.27.886135 — physiology — Posted on 2019-12-28

182 Serotonergic Axons as Fractional Brownian Motion Paths: Insights into the Self-organization of Regional Densities

Janusonis, S.; Detering, N.; Metzler, R.; Vojta, T.

10.1101/2019.12.27.889725 — neuroscience — Posted on 2019-12-28

183 Statistical Agnostic Mapping: A Framework In Neuroimaging Based On Concentration Inequalities

Gorriz, J. M.

10.1101/2019.12.27.889436 — neuroscience — Posted on 2019-12-28

184 Lifetime of a structure evolving by cluster aggregation and particle loss, and application to postsynaptic scaffold domains

Hakim, V.; Ranft, J.

10.1101/2019.12.27.889196 — neuroscience — Posted on 2019-12-28

185 Neuropeptide VF neurons promote sleep via the serotonergic raphe

Lee, D. A.; Oikonomou, G.; Cammidge, T.; Hong, Y.; Prober, D. A.

10.1101/2019.12.27.889402 — neuroscience — Posted on 2019-12-28

186 Replication timing maintains the global epigenetic state in human cells.

Klein, K. N.; Zhao, P. A.; Lyu, X.; Bartlett, D. A.; Singh, A.; Tasan, I.; Watts, L. P.; Hiraga, S.-i.; Natsume, T.; Zhou, X.; Leung, D.; Kanemaki, M.; Donaldson, A. D.; Zhao, H.; Dalton, S.; Corces, V.; Gilbert, D. M.

10.1101/2019.12.28.890020 — molecular biology — Posted on 2019-12-28

187 Game Theory Applications in Host-Microbe Interactions: Mycobacterium tuberculosis infection as an example

Sharebiani, H.; Hajimiri, S.; Abbasnia, S.; Soleimanpour, S.; Asnaashari, A. M. H.; Valizadeh, N.; Derakhshan, M.; Pilpa, R.; Firouzeh, A.; Ghazvini, K.; Amel Jamehdar, S.; Rezaee, S. A. R.

10.1101/2019.12.26.888602 — microbiology — Posted on 2019-12-28

188 ISG15/USP18/STAT2 is a molecular hub regulating autocrine IFN I-mediated control of Dengue and Zika virus replication

Espada, C. E.; da Rocha, E. L.; dos Santos, A. A.; Soares, Z. G.; Malaquias, G.; Patricio, D. d. O.; Kozlova, E. G.; dos Santos, P. F.; Bordignon, J.; Sanford, T. J.; Fajardo, T.; Sweeney, T.; Bafica, A.; Mansur, D. S.

10.1101/784678 — immunology — Posted on 2019-12-28

189 Influence Of Urbanization On Ecological Status Of River In Amhara Region, Ethiopia 2019

Alie, M. S.

10.1101/2019.12.28.889949 — ecology — Posted on 2019-12-28

190 Live and inanimate predator-associated cues suppress the population of sap-feeding prey and induce polyphenism

Khudr, M. S.; Dobberke, T.; Buzhdygan, O. Y.; Wurst, S.

10.1101/2019.12.27.889634 — ecology — Posted on 2019-12-28

191 For running or burying -- The toe fringe of Phrynocephalus mystaceus is important

Zheng, P.; Liang, T.; An, J.; Shi, L.

10.1101/2019.12.26.889105 — animal behavior and cognition — Posted on 2019-12-28

192 Antigen-driven PD1+Tox+Eomes+ and PD1+Tox+BHLHE40+ synovial T lymphocytes regulate chronic inflammation in situ

Maschmeyer, P.; Heinz, G. A.; Skopnik, C.; Lutter, L.; Mazzoni, A.; Heinrich, F.; von Stuckrad, S. L.; Wirth, L. E.; Tran, C. L.; Riedel, R.; Lehmann, K.; Sakwa, I.; Cimaz, R.; Giudici, F.; Mall, M. A.; Enghard, P.; Vastert, B.; Chang, H.-D.; Durek, P.; Annunziato, F.; van Wijk, F.; Radbruch, A.; Kallinich, T.; Mashreghi, M.-F.

10.1101/2019.12.27.884098 — immunology — Posted on 2019-12-28

193 The Ortholog Conjecture Revisited: the Value of Orthologs and Paralogs in Function Prediction

Stamboulian, M.; Guerrero, R. F.; Hahn, M. W.; Radivojac, P.

10.1101/2019.12.27.889691 — bioinformatics — Posted on 2019-12-28

194 Distance preserving dimension reduction withlocal-topology based scaling for improvedclassification of Biomedical data-sets.

Khosla, K.; Jha, I. P.; KUMAR, V.

10.1101/2019.12.27.889337 — bioinformatics — Posted on 2019-12-28

195 Oxygen consumption of drift-feeding rainbow trout: the energetic tradeoff between locomotion and feeding in flow

Johansen, J. L.; Akanyeti, O.; Liao, J. C.

10.1101/2019.12.26.889055 — physiology — Posted on 2019-12-28

196 Diet-induced loss of adipose Hexokinase 2 triggers hyperglycemia

Shimobayashi, M.; Shetty, S.; Frei, I. C.; Wölnerhanssen, B. K.; Weissenberger, D.; Dietz, N.; Thomas, A.; Ritz, D.; Meyer-Gerspach, A. C.; Maier, T.; Hay, N.; Peterli, R.; Rohner, N.; Hall, M. N.

10.1101/2019.12.28.887794 — physiology — Posted on 2019-12-28

197 Spontaneous and automatic processing of magnitude and parity information of Arabic digits: A frequency-tagging EEG study.

Guillaume, M.; Poncin, A.; Schiltz, C.; Van Rinsveld, A.

10.1101/2019.12.26.888651 — neuroscience — Posted on 2019-12-28

198 Selective and invariant features of neural response surfaces measured with principal curvature

Golden, J. R.; Vilankar, K. P.; Field, D. J.

10.1101/2019.12.26.888933 — neuroscience — Posted on 2019-12-28

199 Transgenic mouse facial nerve model of synkinesis

Ahmed, M. M.; Deich, A. D.; Balfour, G. C.; Laury, A.; Lorin, A.; Silliman, D. T.; Williams, R. L.

10.1101/2019.12.27.877795 — neuroscience — Posted on 2019-12-28

200 Characterization of human-iPSCs derived spinal motor neurons by single-cell RNA sequencing

Thiry, L.; Hamel, R.; Pluchino, S.; Durcan, T.; Stifani, S.

10.1101/2019.12.28.889972 — neuroscience — Posted on 2019-12-28

201 Deep, soft, and dark sounds induce autonomous sensory meridian response

Koumura, T.; Nakatani, M.; Liao, H.-I.; Kondo, H. M.

10.1101/2019.12.28.889907 — neuroscience — Posted on 2019-12-28

202 CSF1R inhibition by small molecule inhibitor affects hematopoiesis and the function of macrophages.

Lei, F.; Cui, N.; Zhou, C.; Chodosh, J.; Vavvas, D. G.; Paschalis, E. I.

10.1101/2019.12.27.889469 — neuroscience — Posted on 2019-12-28

203 A wake-active locomotion circuit depolarizes a sleep-active neuron to switch on sleep

Maluck, E.; Busack, I.; Besseling, J.; Masurat, F.; Turek, M.; Busch, K. E.; Bringmann, H.

10.1101/681536 — neuroscience — Posted on 2019-12-28

204 Increased variability but intact integration during visual navigation in Autism Spectrum Disorder

Noel, J.-P.; Lakshminarasimhan, K. J.; Park, H.; Angelaki, D.

10.1101/2019.12.28.890004 — neuroscience — Posted on 2019-12-28

205 microRNA profiling of mouse cortical progenitors and neurons reveals miR-486-5p as a novel regulator of neurogenesis

Dori, M.; Cavalli, D.; Lesche, M.; Massalini, S.; Haj Abdullah Alieh, L.; Cardoso de Toledo, B.; Khudayberdiev, S.; Schratt, G.; Calegari, F.

10.1101/2019.12.27.889170 — neuroscience — Posted on 2019-12-28

206 Arrhythmic gut microbiome signatures for risk profiling of Type-2 Diabetes

Reitmeier, S.; Kiessling, S.; Clavel, T.; List, M.; Almeida, E. L.; Ghosh, T. G.; Neuhaus, K.; Troll, M.; Grallert, H.; Rathmann, W.; Linkohr, B.; Franke, A.; Le Roy, C. I.; Bell, J.; Spector, T.; Baumbach, J.; O'Toole, P.; Peters, A.; Haller, D.

10.1101/2019.12.27.889865 — microbiology — Posted on 2019-12-28

207 Culex saltanensis and Culex interfor (Diptera: Culicidae) are susceptible and competent to transmit St. Louis encephalitis virus (Flavivirus: Flaviviridae) in central Argentina.

Beranek, M.; Quaglia, A.; Peralta, G.; Flores, F.; Stein, M.; Diaz, A.; Almiron, W.; Contigiani, M.

10.1101/722579 — microbiology — Posted on 2019-12-28

208 Olfactory receptors tuned to volatile mustard oils in drosophilid flies

Matsunaga, T.; Reisenman, C. E.; Goldman-Huertas, B.; Brand, P.; Miao, K.; Suzuki, H.; Ramirez, S. R.; Whiteman, N. K.

10.1101/2019.12.27.889774 — evolutionary biology — Posted on 2019-12-28

209 Validation of a Mathematical Model of Cancer Incorporating Spontaneous and Induced Evolution to Drug Resistance

Gevertz, J. L.; Greene, J. M.; Sontag, E. D.

10.1101/2019.12.27.889444 — cancer biology — Posted on 2019-12-28

210 Heterogeneous T cell motility behaviors emerge from a coupling between speed and turning in vivo

Jerison, E. R.; Quake, S. R.

10.1101/785964 — biophysics — Posted on 2019-12-28

211 Maximization of non-nitrogenous metabolite production in E. coli using population systems biology

Rajagopal, S.; Ghatak, A.; Mookherjee, D.; Hmar, R. V.; Shanbhag, A. P.; Venkataraman, J.; Katagihallimath, N.; S, R. K.; Datta, S.

10.1101/2019.12.27.888545 — bioengineering — Posted on 2019-12-28

212 iPromoter-BnCNN: a Novel Branched CNN Based Predictor for Identifying and Classifying Sigma Promoters

Amin, R.; Rahman, C. R.; Ahmed, S.; Sifat, M. H. R.; Liton, M. N. K.; Rahman, M. M.; Shatabda, S.

10.1101/2019.12.27.884965 — genomics — Posted on 2019-12-28

213 z-STED imaging and spectroscopy to investigate nanoscale membrane structure and dynamics

Barbotin, A.; Urbancic, I.; Galiani, S.; Eggeling, C.; Booth, M.; Sezgin, E.

10.1101/2019.12.28.889923 — biophysics — Posted on 2019-12-28

214 Simulation of closed-loop deep brain stimulation control schemes for suppression of pathological beta oscillations in Parkinson's disease

Fleming, J. E.; Dunn, E.; Lowery, M.

10.1101/2019.12.26.880781 — bioengineering — Posted on 2019-12-28

215 Neurophysiological Correlates of the Dunning-Kruger Effect Reveal Contributions of Episodic Memory to Metacognitive Judgments of Illusory Superiority

Muller, A.; Sirianni, L.; Addante, R. J.

10.1101/2019.12.26.888511 — neuroscience — Posted on 2019-12-28

216 Campylobacter jejuni motility integrates specialized cell shape, flagellar filament, and motor, to coordinate action of its opposed flagella in viscous media

Cohen, E. J.; Daisuke, N.; Kabata, Y.; Hendrixson, D. R.; Nishizaka, T.; Beeby, M.

10.1101/2019.12.26.888701 — microbiology — Posted on 2019-12-28

217 Arginase Inhibition Supports Survival and Differentiation of Neuronal Precursors in Adult Alzheimer's Disease Mice

Polis, B.; Gurevich, V.; Bloch, N.; Samson, A. O.

10.1101/2019.12.26.888727 — neuroscience — Posted on 2019-12-28

218 Opponent regulation of action performance and timing by striatonigral and striatopallidal pathways

Bakhurin, K. I.; Li, X.; Friedman, A. D.; Lusk, N. A.; Watson, G.; Kim, N.; Yin, H. H.

10.1101/2019.12.26.889030 — neuroscience — Posted on 2019-12-28

219 DNA methylation across the genome in aged human skeletal muscle tissue and muscle stem cells: The role of HOX genes and physical activity

10.1101/2019.12.27.886135 — physiology — Posted on 2019-12-28

220 Stimulus dependent relationships between behavioral choice and sensory neural responses

Chicharro, D.; Panzeri, S.; Haefner, R. M.

10.1101/2019.12.27.889550 — neuroscience — Posted on 2019-12-28

221 Exploring the Conformational Transition Between the Fully Folded and Locally Unfolded Substates of the Escherichia coli Thiol Peroxidase

Vazquez, D. S.; Zeida, A.; Agudelo, W. A.; Montes, M.; Ferrer-Sueta, G.; Santos, J.

10.1101/2019.12.26.888669 — biophysics — Posted on 2019-12-28

222 Combining molecular dynamics simulations with small-angle X-ray and neutron scattering data to study multi-domain proteins in solution

Larsen, A. H.; Wang, Y.; Bottaro, S.; Grudinin, S.; Arleth, L.; Lindorff-Larsen, K.

10.1101/2019.12.26.888834 — biophysics — Posted on 2019-12-28

223 Activity and cytosolic Na+ regulates synaptic vesicle endocytosis

Zhu, Y.; Li, D.; Huang, H.

10.1101/2019.12.27.889790 — neuroscience — Posted on 2019-12-28

224 Trehalose Stabilizing Protein in a Water Replacement Scenario: Insights from Molecular Dynamics Simulation

Shao, Q.; Wang, J.; Zhu, W.

10.1101/2019.12.27.889063 — biophysics — Posted on 2019-12-28

225 The voltage-sensing mechanism of the KvAP channel involves breaking of the S4 helix

Bignucolo, O.; Berneche, S.

10.1101/2019.12.28.889881 — bioinformatics — Posted on 2019-12-28

226 Evidence for novel transient clusters of cholinergic ganglion cells in the neonatal mouse retina

de Montigny, J.; Krishnamoorthy, V.; Rozenblit, F.; Gollisch, T.; Sernagor, E.

10.1101/2019.12.27.888792 — neuroscience — Posted on 2019-12-28

227 Touch Induces Local Mechanical Strain in C. elegans Sensory Neurons

Nekimken, A. L.; Pruitt, B. L.; Goodman, M. B.

10.1101/2019.12.27.889766 — neuroscience — Posted on 2019-12-28

228 Chemical transcription roadblocking for nascent RNA display

Strobel, E. J.; Lis, J. T.; Lucks, J. B.

10.1101/2019.12.26.888743 — biochemistry — Posted on 2019-12-28

229 Type I interferons act directly on nociceptors to produce pain sensitization: Implications for viral infection-induced pain

Barragan-Iglesias, P.; Franco-Enzastiga, U.; Jeevakumar, V.; Wangzhou, A.; Granados-Soto, V.; Campbell, Z. T.; Dussor, G.; Price, T. J.

10.1101/2019.12.27.889568 — neuroscience — Posted on 2019-12-28

230 A chromosome-level genome assembly for the beet armyworm (Spodoptera exigua) using PacBio and Hi-C sequencing

Zhang, F.; Zhang, J.; Yang, Y.; Wu, Y.

10.1101/2019.12.26.889121 — genomics — Posted on 2019-12-28

231 Nanopore sequencing of native adeno-associated virus single-stranded DNA using a transposase-based rapid protocol

Radukic, M. T.; Brandt, D.; Haak, M.; Müller, K. M.; Kalinowski, J.

10.1101/2019.12.27.885319 — genomics — Posted on 2019-12-28

232 Principles for rational Cas13d guide design

Wessels, H.-H.; Mendez-Mancilla, A.; Guo, X.; Legut, M.; Daniloski, Z.; Sanjana, N. E.

10.1101/2019.12.27.889089 — genomics — Posted on 2019-12-28

233 Viral fitness determines the magnitude of transcriptomic and epigenomic reprogramming of defense responses in plants

Correa, R. L.; Sanz-Carbonell, A.; Kogej, Z.; Muller, S.; Lopez-Mogollon, S.; Gomez, G.; Baulcombe, D.; Elena, S. F.

10.1101/2019.12.26.888768 — evolutionary biology — Posted on 2019-12-28

234 Multiple merger genealogies in outbreaks of Mycobacterium tuberculosis

Menardo, F.; Gagneux, S.; Freund, F.

10.1101/2019.12.21.885723 — evolutionary biology — Posted on 2019-12-28

235 Optimal evolutionary control for artificial selection on molecular phenotypes

Nourmohammad, A.; Eksin, C.

10.1101/2019.12.27.889592 — evolutionary biology — Posted on 2019-12-28

236 Longitudinal epi-transcriptome profiling reveals the crucial role of m6A in prenatal skeletal muscle development of pigs

Zhang, X.; Yao, Y.; Han, J.; Yang, Y.; Chen, Y.; Tang, Z.; Gao, F.

10.1101/2019.12.27.888560 — genetics — Posted on 2019-12-28

237 SopB- and SifA-dependent shaping of the Salmonella-containing vacuole proteome in the social amoeba Dictyosteliumdiscoideum

Valenzuela, C.; Gil, M.; Urrutia, I. M.; Sabag, A.; Enninga, J.; Santiviago, C. A.

10.1101/2019.12.23.887745 — microbiology — Posted on 2019-12-28

238 A PI3K-WIPI2 positive feedback loop allosterically activates LC3 lipidation in autophagy

Fracchiolla, D.; Chang, C.; Hurley, J. H.; Martens, S.

10.1101/2019.12.18.880591 — biochemistry — Posted on 2019-12-28

239 Kilohertz two-photon fluorescence microscopy imaging of neural activity in vivo

Wu, J.; liang, Y.; Chan, S.; Hsu, C.-L.; Chavarha, M.; Evans, S.; Shi, D.; Lin, M.; Tsia, K.; Ji, N.

10.1101/543058 — neuroscience — Posted on 2019-12-28

240 Antioxidant and antimicrobial activities on uropathogenic bacteria of Asteraceae medicinal plants

Phan, T. C.; Le, T. T. T.; Hoang, H. T. V.; Nguyen, T.-A.

10.1101/2019.12.25.888404 — microbiology — Posted on 2019-12-28

241 SHARP: Single-cell RNA-seq Hyper-fast and Accurate Processing via Ensemble Random Projection

Wan, S.; Kim, J.; Won, K. J.

10.1101/461640 — bioinformatics — Posted on 2019-12-28

242 Laminin alpha 5 is Necessary for Mammary Epithelial Growth and Function by Maintaining Luminal Epithelial Cell Identity

Englund, J. I.; Cojoc, H.; Blaas, L.; Ritchie, A. V.; Pentinmikko, N.; Dohla, J.; Munne, P.; Patarroyo, M.; Klefstrom, J.; Ivaska, J.; Katajisto, P.

10.1101/2019.12.27.889451 — cell biology — Posted on 2019-12-27

243 APOBEC3A Catalyzes Mutation and Drives Carcinogenesis In Vivo

Law, E.; Levin-Klein, R.; Jarvis, M.; Kim, H.; Argyris, P.; Carpenter, M.; Starrett, G.; Larson, L.; Burns, M.; Vogel, R.; Stavrou, S.; Aguilera, A.; Wagner, S.; Largaespada, D.; Starr, T.; Ross, S. R.; Harris, R.

10.1101/2019.12.27.889345 — cancer biology — Posted on 2019-12-27

244 Cerebellum-specific deletion of the GABAA receptor δ subunit alters anxiety-like, social and maternal behaviors without affecting motor performance

Rudolph, S.; Guo, C.; Pashkovski, S. L.; Osorno, T.; Gillis, W. F.; Krauss, J. M.; Nyitrai, H.; Flaquer, I.; El-Rifai, M.; Datta, S. R.; Regehr, W. G.

10.1101/2019.12.27.889014 — neuroscience — Posted on 2019-12-27

245 Perturbation analysis of a multi-morphogen Turing Reaction-Diffusion stripe patterning system reveals key regulatory interactions

Economou, A. D.; Monk, N. A. M.; Green, J. B. A.

10.1101/2019.12.27.889493 — developmental biology — Posted on 2019-12-27

246 H3K27me3 natural variation selectively marks genes predicted to be important for differentiation in unicellular algae

Zhao, X.; Rastogi, A.; Deton Cabanillas, A. F.; Ait Mohamed, O.; Cantrel, C.; Lombard, B.; Murik, O.; Genovesio, A.; Bowler, C.; Bouyer, D.; Loew, D.; Lin, X.; Veluchamy, A.; Vieira, F. R. J.; Tirichine, L.

10.1101/2019.12.26.888800 — cell biology — Posted on 2019-12-27

247 Citrullination regulates wound responses and tissue regeneration in zebrafish

Huttenlocher, A.; Golenberg, N.; Squirrell, J.; Bennin, D.; RIndy, J.; Pistono, P.; Eliceiri, K.; Shelef, M.; Kang, J.

10.1101/2019.12.27.889378 — cell biology — Posted on 2019-12-27

248 The Calcineurin-TFEB-p62 Pathway Mediates the Activation of Cardiac Macroautophagy by Proteasomal Malfunction

Pan, B.; Parajuli, N.; Tian, Z.; Li, J.; Wu, P.; Lewno, M. T.; Bedford, L.; Mayer, R. J.; Fang, J.; Liu, J.; Cui, T.; Su, H.; Wang, X.

10.1101/2019.12.27.889519 — cell biology — Posted on 2019-12-27

249 Oxygen-generated spatial distribution of cell population links to p53 status

Taxak, S.; Pati, U.

10.1101/2019.12.27.889394 — cancer biology — Posted on 2019-12-27

250 Abrogation of RAB27A expression transiently affects melanoma cell proliferation

Guo, D.; Beaumont, K. A.; Sharp, D. M.; Lui, G. Y. L.; Weninger, W.; Haass, N. K.; Tikoo, S.

10.1101/2019.12.27.889329 — cancer biology — Posted on 2019-12-27

251 XFlow: An algorithm for extracting ion chromatograms

Smith, R.; Gutierrez, M.

10.1101/2019.12.27.889253 — bioinformatics — Posted on 2019-12-27

252 A metal artifact reduction method for small field of view CT imaging.

Choi, S.; Moon, S.; Baek, J.

10.1101/2019.12.27.889204 — bioengineering — Posted on 2019-12-27

253 Tackling misinformation in agriculture

Stroud, J. L.

10.1101/2019.12.27.889279 — scientific communication and education — Posted on 2019-12-27

254 A non-invasive digital biomarker for the detection of rest disturbances in the SOD1G93A mouse model of ALS

Golini, E.; Rigamonti, M.; Iannello, F.; De Rosa, C.; Scavizzi, F.; Raspa, M.; Mandillo, S.

10.1101/2019.12.27.889246 — neuroscience — Posted on 2019-12-27

255 QTL-Seq Identifies QTL for Relative Electrical Conductivity Associated with Heat Tolerance in Bottle Gourd (Lagenaria Siceraria)

Song, H.; Huang, Y.; Gu, B.

10.1101/2019.12.27.889261 — molecular biology — Posted on 2019-12-27

256 Proteomics of Extracellular Vesicles Produced by Granulicatella Species that cause Infective Endocarditis

Alkandari, S. A.; Bhardwaj, R. G.; Ellepola, A.; Karched, M.

10.1101/2019.12.27.889220 — microbiology — Posted on 2019-12-27

257 QTL Mapping and integration as well as candidate gene prediction for branch number in soybean

Yang, Y.; Lei, Y.; Bai, z.; Wei, Y.; Zhang, R.

10.1101/2019.12.27.889287 — genetics — Posted on 2019-12-27

258 Improving Probabilistic Infectious Disease Forecasting Through Coherence

Gibson, G.; Moran, K.; Reich, N.; Osthus, D.

10.1101/2019.12.27.889212 — bioinformatics — Posted on 2019-12-27

259 Time-ResNeXt for epilepsy recognition based on EEG signals

wang, s.; wang, s.; wang, y.

10.1101/2019.12.27.889238 — bioinformatics — Posted on 2019-12-27

260 Relating brain connectivity with persistent symptoms in pediatric concussion

Iyer, K. K.; Barlow, K. M.; Brooks, B.; Ofoghi, Z.; Zalesky, A.; Cocchi, L.

10.1101/539825 — neuroscience — Posted on 2019-12-27

261 QTL Mapping and integration as well as candidate gene prediction for branch number in soybean

Yang, Y.; Lei, Y.; Bai, z.; Wei, Y.; Zhang, R.

10.1101/2019.12.27.889287 — genetics — Posted on 2019-12-27

262 Alpha oscillations for processing saliency are generated by common cortical networks in visual attention tasks spanning wide spatial and spatio-temporal scales

Ghosh, P.; Roy, D.; Banerjee, A.

10.1101/2019.12.25.888446 — neuroscience — Posted on 2019-12-27

263 Double dissociation of fMRI activity in the caudate nucleus supports de novo motor skill learning

Choi, Y.; Shin, E. Y.; Kim, S.

10.1101/2019.12.24.887786 — neuroscience — Posted on 2019-12-27

264 A Machine Learning Approach to the Recognition of Brazilian Atlantic Forest Parrot Species

Padovese, B.; Padovese, L.

10.1101/2019.12.24.888180 — ecology — Posted on 2019-12-27

265 The Feasibility of Predicting Impending Malignant Ventricular Arrhythmias on the basis of Signal Complexity of Heartbeat Intervals

Chen, Z.; Kido, K.; Ono, N.; Altaf-Ul-Amin, M.; Kanaya, S.; Huang, M.

10.1101/2019.12.25.888321 — bioinformatics — Posted on 2019-12-27

266 A Novel Chloroplast Super-Complex Consisting of the ATP Synthase and Photosystem I Reaction Center

Bhaduri, S.; Singh, S. K.; Cohn, W.; Hasan, S. S.; Whitelegge, J. P.; Cramer, W. A.

10.1101/2019.12.25.888495 — biochemistry — Posted on 2019-12-27

267 Multi-Parametric Profiling of Endothelial Cell Networks Reveals Functional Role of Glutamate Receptors in Angiogenesis

Sailem, H. Z.; Al Haj Zen, A.

10.1101/2019.12.25.888479 — systems biology — Posted on 2019-12-27

268 Identifying triplex binding rules in vitro leads to creation of a new synthetic regulatory tool in vivo

Kaufmann, B.; Willinger, O.; Eden, N.; Kermas, L.; Anavy, L.; Solomon, O.; Atar, O.; Yakhini, Z.; Goldberg, S.; Amit, R.

10.1101/2019.12.25.888362 — synthetic biology — Posted on 2019-12-27

269 Haloperidol-induced impairment on working memory capacity affecting long term memory performance: the binding hypothesis

Guarnieri, R. V.; Alves, M. V.; Nogueira, A. M. L.; Tudesco, I. d. S. S.; Galduroz, J. C.; Covolan, L.; Bueno, O. F. A.

10.1101/2019.12.24.888073 — neuroscience — Posted on 2019-12-27

270 Low-dose ethanol produces mixed effects on cortico-hippocampal theta rhythms and modifies hippocampal theta frequency through multiple mechanisms

Young, C. K.; McNaughton, N.

10.1101/2019.12.25.888487 — neuroscience — Posted on 2019-12-27

271 Temporal interference stimulation targets deep brain regions by modulating neural oscillations

Esmaeilpour, Z.; Kronberg, G.; Parra, L. C.; Bikson, M.

10.1101/2019.12.25.888412 — neuroscience — Posted on 2019-12-27

272 Modality-specific and multisensory mechanisms of spatial attention and expectation

Zuanazzi, A.; Noppeney, U.

10.1101/847921 — neuroscience — Posted on 2019-12-27

273 Antioxidant and antimicrobial activites on uropathogenic bacteria of Asteraceae medicinal plants

Phan, T. C.; Le, T. T. T.; Hoang, H. T. V.; Nguyen, T.-A.

10.1101/2019.12.25.888404 — microbiology — Posted on 2019-12-27

274 A genome wide analysis of Escherichia coli responses to fosfomycin using TraDIS-Xpress reveals novel roles for the phosphonate and phosphate transport systems

Yasir, M.; Turner, A. K.; Bastkowski, S.; Charles, I. G.; Webber, M. A.

10.1101/2019.12.23.887760 — microbiology — Posted on 2019-12-27

275 Capture and visualization of live Mycobacterium tuberculosis bacilli from tuberculosis bioaerosols

Dinkele, R.; Gessner, S.; Koch, A. S.; Morrow, C.; Gqada, M.; Kamariza, M.; Bertozzi, C.; Smith, B.; McLoud, C.; Kamholz, A.; Bryden, W.; Call, C.; Mizrahi, V.; Wood, R.; Warner, D. F.

10.1101/2019.12.23.887729 — microbiology — Posted on 2019-12-27

276 CNV-BAC: Copy Number Variation Detection in Bacterial Circular Genome

Wu, L.; Wang, H.; Xia, Y.; Xi, R.

10.1101/2019.12.24.887992 — bioinformatics — Posted on 2019-12-27

277 Redox-mediated regulation of a labile, evolutionarily conserved cross-β structure formed by the TDP43 low complexity domain

Lin, Y.; Zhou, X.; Kato, M.; Liu, D.; Ghaemmaghami, S.; Tu, B. P.; McKnight, S. L.

10.1101/2019.12.24.885962 — biochemistry — Posted on 2019-12-27

278 Chloroplast SRP43 Subunit Prevents Aggregation of Proteins

Furr, M.; Okoto, P.; Moradi, M.; Heyes, C.; Henry, R.; Suresh Kumar, T. K.

10.1101/2019.12.24.888255 — biochemistry — Posted on 2019-12-27

279 Probing behavior of Diaphorina citri (Hemiptera: Liviidae) on Valencia orange influenced by sex, color, and size

Ebert, T.; Rogers, M. E.

10.1101/2019.12.24.885178 — animal behavior and cognition — Posted on 2019-12-27

280 Eukaryotic-like ribosomal RNA region in Lokiarchaeota

Penev, P. I.; Fakhretaha-Aval, S.; Patel, V. J.; Cannone, J. J.; Gutell, R. R.; Petrov, A. S.; Williams, L. D.; Glass, J. B.

10.1101/2019.12.25.888164 — evolutionary biology — Posted on 2019-12-27

281 A method to determine the double bond position in unsaturated fatty acids by solvent plasmatization using liquid chromatography-mass spectrometry

Takashima, S.; Toyoshi, K.; Yamamoto, T.; Shimozawa, N.

10.1101/2019.12.24.875385 — biochemistry — Posted on 2019-12-27

282 Interactive mapping of language and memory with the GE2REC protocol

Banjac, S.; Roger, E.; Cousin, E.; Perrone-Bertolotti, M.; Haldin, C.; Pichat, C.; Lamalle, L.; Minotti, L.; Kahane, P.; Baciu, M.

10.1101/2019.12.24.888040 — neuroscience — Posted on 2019-12-27

283 Object novelty and value coding segregate across functionally connected brain networks

Ghazizadeh, A.; Fakharian, M.; Amini, A.; Griggs, W.; Leopold, D. A.; Hikosaka, O.

10.1101/2019.12.25.887976 — neuroscience — Posted on 2019-12-27

284 Anterograde Trans-Synaptic AAV Strategies for Probing Neural Circuitry

Zingg, B.; Peng, B.; Huang, J. J.; Tao, H. W.; Zhang, L. I.

10.1101/2019.12.24.888172 — neuroscience — Posted on 2019-12-27

285 No title, no theme: The joined neural space between speakers and listeners during production and comprehension of multi sentence discourse

Heidlmayr, K.; Weber, K.; Takashima, A.; Hagoort, P.

10.1101/2019.12.25.884775 — neuroscience — Posted on 2019-12-27

286 Separation of Bioactive Small Molecules, Peptide from Natural Products and Proteins from Pathogenic Microbe by Rotofor-based Preparative Isoelectric Focusing (IEF) Method

Veerapandian, R.; Paudyal, A.; Chang, A.; Vediyappan, G.

10.1101/2019.12.23.887711 — microbiology — Posted on 2019-12-27

287 Molecular Phylogenetic Analysis of 16S rRNA Sequences Identified Two lineages of H. pylori Strains Detected from Different Regions in Sudan Suggestive of Differential Evolution

Idris, A. B.; Hassan, H. G.; Ali, M. A. S.; Eltaher, S. M.; Idris, L. B.; Altayb, H. N.; Abass, A. M.; Ibrahim, M. M. A.; Ibrahim, E.-A. M.; Hassan, M. A.

10.1101/2019.12.25.888396 — microbiology — Posted on 2019-12-27

288 A novel allele of ASY3 promotes meiotic stability in autotetraploid Arabidopsis lyrata

Seear, P. J.; France, M. G.; Gregory, C. L.; Heavens, D.; Schmickl, R.; Yant, L.; Higgins, J. D.

10.1101/2019.12.25.888388 — evolutionary biology — Posted on 2019-12-27

289 Bridging theories for ecosystem stability through structural sensitivity analysis of ecological models in equilibrium

Kuiper, J. J.; Kooi, B. W.; Peterson, G. D.; Mooij, W. M.

10.1101/2019.12.24.887901 — ecology — Posted on 2019-12-27

290 Temperature-dependence of metabolic rate in tropical and temperate aquatic insects: support for the Climate Variability Hypothesis in mayflies but not stoneflies.

Shah, A. A.; Woods, H. A.; Havird, J. C.; Encalada, E. C.; Flecker, A. S.; Funk, W. C.; Guayasamin, J. M.; Kondratieff, B. K.; Poff, N. L.; Thomas, S. A.; Zamudio, K. R.; Ghalambor, C. K.

10.1101/2019.12.25.888578 — ecology — Posted on 2019-12-27

291 Chemical map-based prediction of nucleosome positioning using the Bioconductor package nuCpos

Kato, H.; Shimizu, M.; Urano, T.

10.1101/2019.12.25.888305 — bioinformatics — Posted on 2019-12-27

292 LegoBody: facile generation of bispecific and multi-specific antibodies

Lang, S.; Su, Y.; Bidlingmaier, S.; Lee, N.-K.; Liu, B.

10.1101/2019.12.25.888586 — bioengineering — Posted on 2019-12-27

293 The genomic and epigenomic evolutionary history of papillary renal cell carcinomas

Zhu, B.; Poeta, M. L.; Costantini, M.; Zhang, T.; Shi, J.; Sentinelli, S.; Zhao, W.; Pompeo, V.; Cardelli, M.; Alexandrov, B. S.; Otlu, B.; Hua, X.; Jones, K.; Brodie, S.; Toro, J. R.; Yeager, M.; Wang, M.; Hicks, B.; Alexandrov, L. B.; Brown, K. M.; Wedge, D. C.; Chanock, S.; Fazio, V. M.; Gallucci, M.; Landi, M. T.

10.1101/478156 — genomics — Posted on 2019-12-27

294 Mechanisms governing irritant-evoked activation and calcium modulation of TRPA1

Zhao, J.; Lin King, J. V.; Cheng, Y.; Julius, D.

10.1101/2019.12.26.888982 — biophysics — Posted on 2019-12-27

295 G-domain prediction across the diversity of G protein families

Sanghavi, H. M.; Rashmi, R.; Dasgupta, A.; Majumdar, S.

10.1101/2019.12.24.888222 — bioinformatics — Posted on 2019-12-27

296 An experimental workflow identifies nitrogenase proteins ready for expression in plant mitochondria

Okada, S.; Gregg, C. C.; Allen, R. S.; Menon, A.; Hussain, D.; Gillespie, V.; Johnston, E.; Byrne, K.; Colgrave, M.; WOOD, C. C.

10.1101/2019.12.23.887703 — synthetic biology — Posted on 2019-12-27

297 Effect of Exogenous Amino Acids on Yield and Quality of Tartary Buckwheat in Non-saline and Saline-alkali Soil

Song, J.-N.; Wang, Y.-Q.; Li, S.; Li, F.-L.; Hu, Y.-J.; Yang, H.-B.

10.1101/2019.12.24.887778 — physiology — Posted on 2019-12-27

298 The Preferred Period Hypothesis Revisited: Rhythmic Preferences and Motor Tapping Precision in ADHD Adults and Controls

Kliger Amrani, A.; Zion Golumbic, E.

10.1101/2019.12.24.887802 — neuroscience — Posted on 2019-12-27

299 Disconnectome Associated with Progressive Ischemic Periventricular White Matter Lesions

Li, Z.; Dolui, S.; Habes, M.; Bassett, D. S.; Wolk, D.; Detre, J. A.

10.1101/2019.12.24.888081 — neuroscience — Posted on 2019-12-27

300 Visual feature tuning of superior colliculus neural reafferent responses after fixational microsaccades

Khademi, F.; Chen, C.-Y.; Hafed, Z. M.

10.1101/2019.12.24.888149 — neuroscience — Posted on 2019-12-27

301 Sequestration of Methane by Symbiotic Deep-Sea Annelids: Ancient and Future Implications of Redefining the Seep Influence

Goffredi, S. K.; Tilic, E.; Mullin, S. W.; Dawson, K. S.; Keller, A.; Lee, R.; Wu, F.; Levin, L. A.; Rouse, G. W.; Cordes, E.; Orphan, V. J.

10.1101/2019.12.23.887653 — microbiology — Posted on 2019-12-27

302 Sporaefaciens musculi gen. nov., sp. nov., a novel bacterium isolated from the caecum of an obese mouse

Rasmussen, T. S.; Streidl, T.; Hitch, T. C. A.; Wortmann, E.; Deptula, P.; Hansen, M.; Nielsen, D. S.; Clavel, T.; Vogensen, F. K.

10.1101/2019.12.21.885665 — microbiology — Posted on 2019-12-27

303 Physical mechanisms of amyloid nucleation on fluid membranes

Krausser, J.; Knowles, T. P. J.; Saric, A.

10.1101/2019.12.22.886267 — biophysics — Posted on 2019-12-27

304 Causes and consequences of facultative sea crossing in a soaring migrant

Becciu, P.; Rotics, S.; Horvitz, N.; Kaatz, M.; Fiedler, W.; Zurell, D.; Flack, A.; Jeltsch, F.; Wikelski, M.; Nathan, R.; Sapir, N.

10.1101/758102 — ecology — Posted on 2019-12-27

305 Biophysical models of cis-regulation as interpretable neural networks

Tareen, A.; Kinney, J. B.

10.1101/835942 — bioinformatics — Posted on 2019-12-27

306 Biodiversity of Magnetotactic Bacteria in the freshwater Lake Beloe Bordukovskoe, Russia

Koziaeva, V. V.; Alekseeva, L. M.; Uzun, M. M.; Leao, P.; Sukhacheva, M. V.; Patutina, E. O.; Kolganova, T.; Grouzdev, D. S.

10.1101/682252 — microbiology — Posted on 2019-12-27

307 Same Equilibrium. Different Kinetics. Protein Functional Consequences.

Schmid, S.; Hugel, T.

10.1101/838938 — biophysics — Posted on 2019-12-27

308 Competitive Inhibition of Cortisol by Prostaglandins at the Ligand Binding Domain of Glucocorticoid Receptors

Schaper, C.

10.1101/851501 — molecular biology — Posted on 2019-12-27

309 Elaboration of the corticosteroid synthesis pathway in primates through a multi-step enzyme

Olson-Manning, C. F.

10.1101/2019.12.25.888461 — evolutionary biology — Posted on 2019-12-27

310 ERK-mediated mechanochemical waves direct collective cell polarization

Hino, N.; Rossetti, L.; Marin-Llaurado, A.; Aoki, K.; Trepat, X.; Matsuda, M.; Hirashima, T.

10.1101/2019.12.25.888552 — cell biology — Posted on 2019-12-27

311 Transcription levels of a long noncoding RNA orchestrate opposing regulatory and cell fate outcomes in yeast

Moretto, F.; Wood, N. E.; Chia, M.; Li, C.; Luscombe, N.; van Werven, F.

10.1101/2019.12.24.887935 — biochemistry — Posted on 2019-12-27

312 Microglia depletion disrupts normal functional development of adult-born neurons in the olfactory bulb

Wallace, J. L.; Lord, J.; Dissing-Olesen, L.; Stevens, B.; Murthy, V. N.

10.1101/714337 — neuroscience — Posted on 2019-12-27

313 Transcriptome analysis of Tartary Buckwheat reveals the differential expression of salt pathway genes

Song, J.-N.; Liu, X.-H.; Wang, Y.-Q.; Yang, H.-B.

10.1101/869263 — genomics — Posted on 2019-12-27

314 Altitude-wise analysis of co-occurrence networks of mitochondrial genome in Asian population

Verma, R. K.; Giuliani, C.; Kalyakuina, A.; Kachhvah, A. D.; Ivanchenko, M.; Jalan, S.

10.1101/2019.12.21.885905 — systems biology — Posted on 2019-12-27

315 Is N-Hacking Ever OK? A Simulation-based study

Reinagel, P.

10.1101/2019.12.12.868489 — scientific communication and education — Posted on 2019-12-27

316 Different salicylic and jasmonic acids imbalances are involved in the oxidative stress-mediated cell death, induced by fumonisin B1 in maize seedlings with contrasting resistance to Fusarium verticillioides ear rot in the field.

Otaiza Gonzalez, S. N.; Mary, V.; Arias, S.; Bertrand, L.; Velez, P.; Rodriguez, M. G.; Rubinstein, H.; Theumer, M.

10.1101/2019.12.25.882597 — plant biology — Posted on 2019-12-27

317 Cytokinin induction by the Jasmonate-induced AP2/ERF115 represses adventitious rooting in Arabidopsis

Lakehal, A.; Dob, A.; Rahneshan, Z.; Novak, O.; Escamez, S.; Alallaq, S.; Strnad, M.; Tuominen, H.; Bellini, C.

10.1101/2019.12.27.886796 — plant biology — Posted on 2019-12-27

318 Auxin transport network underlies xylem bridge formation between the hemi-parasitic plant Phtheirospermum japonicum and host Arabidopsis

Wakatake, T.; Yoshida, S.; Shirasu, K.

10.1101/2019.12.26.889097 — plant biology — Posted on 2019-12-27

319 Molecular characterization and differential expression reveal functional divergence of stress-responsive enzymes in C4 panicoid models, Setaria italica and Setaria viridis

Muthamilarasan, M.; Singh, R. K.; Suresh, B. V.; Dulani, P.; Singh, N. K.; Prasad, M.

10.1101/2019.12.24.887927 — plant biology — Posted on 2019-12-27

320 Neuronal ON/OFF Motion Detection Circuits Underlying Looming-Evoked Escape Behavior in Drosophila

Kyung, Y.; Dewell, R. B.; Dierick, H. A.; Gabbiani, F.

10.1101/2019.12.26.883587 — neuroscience — Posted on 2019-12-27

321 An insulin, AMPK, and steroid hormone-mediated metabolic switch regulates the transition between growth and diapause in C. elegans

Penkov, S.; Raghuraman, B. K.; Erkut, C.; Oertel, J.; Galli, R.; Miranda Ackerman, E. J.; Vorkel, D.; Verbavatz, J.-M.; Koch, E.; Fahmy, K.; Shevchenko, A.; Kurzchalia, T. V.

10.1101/323956 — biochemistry — Posted on 2019-12-27

322 Synthesis and Characterisation of Aqueous Haemoglobin-based Microcapsules Coated by Genipin-Cross-Linked Albumin

Schakowski, K. M.; Linders, J.; Ferenz, K. B.; Kirsch, M.

10.1101/818278 — biochemistry — Posted on 2019-12-27

323 Asymmetry in kinematic generalisation between visual and passive lead-in movements are consistent with a forward model in the sensorimotor system

Howard, I. S.; Franklin, S.; Franklin, D. W.

10.1101/636266 — neuroscience — Posted on 2019-12-27

324 Better tired than lost: turtle ant trail networks favor coherence over shortest paths

Chandrasekhar, A.; Marshall, J. A. R.; Austin, C.; Navlakha, S.; Gordon, D. M.

10.1101/714410 — ecology — Posted on 2019-12-27

325 Sequence Compression Benchmark (SCB) database - a comprehensive evaluation of reference-free compressors for FASTA-formatted sequences

Kryukov, K.; Ueda, M. T.; Nakagawa, S.; Imanishi, T.

10.1101/642553 — bioinformatics — Posted on 2019-12-27

326 Ontario Neurodegenerative Disease Research Initiative (ONDRI): Structural MRI methods & outcome measures

Ramirez, J.; Holmes, M. F.; Scott, C. J. M.; Ozzoude, M.; Adamo, S.; Szilagyi, G. M.; Goubran, M.; Gao, F.; Arnott, S. R.; Lawrence-Dewar, J. M.; Beaton, D.; Strother, S. C.; Munoz, D. P.; Masellis, M.; Swartz, R. H.; Bartha, R.; Symons, S.; Black, S. E.; the ONDRI Investigators,

10.1101/2019.12.13.875823 — neuroscience — Posted on 2019-12-27

327 Zebrafish dazl regulates cystogenesis upstream of the meiotic transition and germline stem cell specification and independent of meiotic checkpoints.

Bertho, S.; Clapp, M.; Banisch, T. U.; Bandemer, J.; Raz, E.; Marlow, F.

10.1101/2019.12.23.887687 — developmental biology — Posted on 2019-12-27

328 Cancer cell CCR2 orchestrates suppression of the adaptive immune response

Fein, M. R.; He, X. Y.; Almeida, A. S.; Bruzas, E.; Pommier, A.; Yan, R.; Eberhardt, A.; Fearon, D. T.; Van Aelst, L.; Wilkinson, J. E.; dos Santos, C. O.; Egeblad, M.

10.1101/390187 — cancer biology — Posted on 2019-12-27

329 Adventures in Multi-Omics I: Combining heterogeneous data sets via relationships matrices

Akdemir, D.; Isidro Sanchez, J.

10.1101/857425 — genomics — Posted on 2019-12-27

330 Single cell transcriptome of CD8+ T cells in multiple cancers reveals comprehensive exhaustion associated mechanisms

Bai, Y.; Chen, Z.; Chen, X.; He, Z.; Long, J.; Lin, S.; Huang, L.; Du, H.

10.1101/2019.12.26.888503 — cancer biology — Posted on 2019-12-27

331 Single-cell RNA-seq data reveals TNBC tumor heterogeneity through characterizing subclone compositions and proportions

Wang, W.; Xu, J.; Wang, S.; Xia, P.; Zhang, L.; Yu, L.; Wu, J.; Song, Q.; Zhang, B.; Xu, C.; Xiao, Y.

10.1101/858290 — cancer biology — Posted on 2019-12-27

332 The turning and barrier course reveals gait parameters for detecting freezing of gait and measuring the efficacy of deep brain stimulation

O'Day, J.; Syrkin-Nikolau, J.; Anidi, C.; Kidzinski, L.; Delp, S.; Bronte-Stewart, H.

10.1101/671479 — neuroscience — Posted on 2019-12-27

333 Deciphering the many maps of the Xingu, an assessment of deforestation from land cover classifications at multiple scales

Kalacska, M.; Arroyo-Mora, J. P.; Lucanus, O.; Sousa, L.; Pereira, T.; Vieira, T.

10.1101/2019.12.23.887588 — ecology — Posted on 2019-12-27

334 Multinational qEEG developmental surfaces

Hu, S.; Ngulugulu, A.; Bosch-Bayard, J.; Bringas-Vega, M. L.; Valdes-Sosa, P. A.

10.1101/2019.12.20.883991 — neuroscience — Posted on 2019-12-27

335 Zebrafish embryonic tissue differentiation is marked by concurrent cell cycle dynamic and gene promoter regulatory changes

Wragg, J. W.; Roos, L.; Vucenovic, D.; Cvetesic, N.; Lenhard, B.; Mueller, F.

10.1101/2019.12.27.884890 — developmental biology — Posted on 2019-12-27

336 Cytoplasmic streaming drifts the polarity cue and specifies the cell polarity in Caenorhabditis elegans zygotes

Kimura, K.; Kimura, A.

10.1101/2019.12.23.887620 — developmental biology — Posted on 2019-12-27

337 Enhancement of gene expression noise due to nonspecific transcription factor binding

Dey, S.; Soltani, M.; Singh, A.

10.1101/2019.12.24.887984 — systems biology — Posted on 2019-12-27

338 No strong evidence that social network index is associated with gray matter volume from a data-driven investigation

Lin, C.; Keles, U.; Tyszka, M. J.; Gallo, M.; Paul, L.; Adolphs, R.

10.1101/2019.12.19.883173 — neuroscience — Posted on 2019-12-27

339 Recalibrating the transcriptomic timetree of jawed vertebrates

Marjanovic, D.

10.1101/2019.12.19.882829 — evolutionary biology — Posted on 2019-12-27

340 Growth factor-mediated coupling between lineage size and cell fate choice underlies robustness of mammalian development

Saiz, N.; Mora-Bitria, L.; Rahman, S.; George, H.; Herder, J. P.; Garcia-Ojalvo, J.; Hadjantonakis, A.-K.

10.1101/2019.12.27.889006 — developmental biology — Posted on 2019-12-27

341 The Drosophila MLR COMPASS-like complex regulates bantam miRNA expression differentially in the context of cell fate

Ford, D.; Zraly, C.; Hertenstein Perez, J.; Dingwall, A.

10.1101/2019.12.24.888214 — developmental biology — Posted on 2019-12-27

342 Mouse Aging Cell Atlas Analysis Reveals Global and Cell Type Specific Aging Signatures

Zhang, M. J.; Pisco, A. O.; Darmanis, S.; Zou, J.

10.1101/2019.12.23.887604 — bioinformatics — Posted on 2019-12-27

343 In vivo characterisation of the toxicological properties of DPhP, one of the main degradation product of aryl phosphate esters.

Ruby, S.; Marin-Saez, J.; Fildier, A.; Bulete, A.; Abdallah, M.; Garcia, J.; Deverchere, J.; Spinner, L.; Giroud, B.; Ibanez, S.; Granjon, T.; Bardel-Danjean, C.; Fervers, B.; Puisieux, A.; Vulliet, E.; Payen-Gay, L.; Vigneron, A. M.

10.1101/2019.12.26.888057 — pharmacology and toxicology — Posted on 2019-12-27

344 Targeted mutagenesis using CRISPR-Cas9 in the chelicerate herbivore Tetranychus urticae

Dermauw, W.; Jonckheere, W.; Riga, M.; Livadaras, I.; Vontas, J.; Van Leeuwen, T.

10.1101/2019.12.25.888032 — molecular biology — Posted on 2019-12-27

345 Molecular dynamics simulation of local structural models of PrPSc reveals how codon 129 polymorphism affects propagation of PrPSc.

Otaki, H.; Taguchi, Y.; Nishida, N.

10.1101/2019.12.25.888289 — molecular biology — Posted on 2019-12-27

346 The mechanosensitive Piezo1 orchestrating angiogenesis is essential in bone fracture repair

Li, J.; Chen, P.; Zhang, G.; Jiang, S.; Ning, Y.; Deng, B.; Pan, X.; Liu, S.; He, Y.; Zhang, L.; Wan, R.; Wu, Z.; He, Q.; Yin, J.; Wang, H.

10.1101/2019.12.23.887661 — systems biology — Posted on 2019-12-27

347 KCNQ channels enable reliable presynaptic spiking and synaptic transmission at high-frequency

Zhang, Y.; Li, D.; Darwish, Y.; Trussell, L. O.; Huang, H.

10.1101/2019.12.26.888875 — neuroscience — Posted on 2019-12-27

348 Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein.

Kobayashi, K.; Shihoya, W.; nishizawa, T.; Kadji, F. M. N.; Aoki, J.; Inoue, A.; Nureki, O.

10.1101/2019.12.23.887737 — molecular biology — Posted on 2019-12-27

349 Clamping, bending, and twisting inter-domain motions in the misfold-recognising portion of UDP glucose:glycoprotein glucosyl-transferase.

Modenutti, C. P.; Blanco Capurro, J. I.; Ibba, R.; Vasiljevic, S.; Hensen, M.; Alonzi, D. S.; Chandran, A. V.; Hill, J. C.; Rushton, J.; Kumar, A.; Rubichi, S.; Lia, A.; Tax, G.; Marti, L.; Santino, A.; Marti, M.; Zitzmann, N.; Roversi, P.

10.1101/2019.12.25.888438 — biochemistry — Posted on 2019-12-27

350 Crystal structure of a human plasma membrane phospholipid flippase

Nakanishi, H.; Irie, K.; Segawa, K.; Hasegawa, K.; Fujiyoshi, Y.; Nagata, S.; Abe, K.

10.1101/2019.12.23.881698 — biochemistry — Posted on 2019-12-27

351 High-K+ causes inner hair cell ribbon synapse degeneration

Zhao, H.-B.; Zhu, Y.; Liu, L.-M.

10.1101/2019.12.23.887596 — neuroscience — Posted on 2019-12-27

352 Sources of predictive information in dynamical neural networks

Candadai, M.; Izquierdo, E. J.

10.1101/2019.12.23.887554 — neuroscience — Posted on 2019-12-27

353 Development of a Protocol to Study Bronchial Smooth Muscle Cells Behavior on a Natural Biologic Bronchial Matrix

Ben Hamouda, S.; Vargas, A.; Boivin, R.; Miglino, M. A.; da Palma, R. K.; Lavoie, J.-P.

10.1101/2019.12.23.878645 — cell biology — Posted on 2019-12-26

354 The transcriptome dynamics of single cells during the cell cycle

Schwabe, D.; Formichetti, S.; Junker, J. P.; Falcke, M.; Rajewsky, N.

10.1101/2019.12.23.887570 — systems biology — Posted on 2019-12-26

355 The Two Amino Acids Proximate to the Renin Cleavage Site of Human Angiotensinogen Do Not Affect Angiotensin II-mediated Functions in Mice

Wu, C.-H.; Wu, C.; Howatt, D. A.; Moorleghen, J. J.; Cassis, L. A.; Daugherty, A.; LU, H. S.

10.1101/2019.12.18.875914 — pathology — Posted on 2019-12-26

356 IRAK1-mediated coincidence detection of microbial signals licenses inflammasome activation

Vayttaden, S. J.; Smelkinson, M.; Ernst, O.; Carlson, R. J.; Sun, J.; Bradfield, C.; Dorrington, M. G.; Liang, J.; Bouladoux, N.; Gottschalk, R. A.; Oh, K.-S.; Pegoraro, G.; Ganesan, S.; De Nardo, D.; Latz, E.; Belkaid, Y.; Varma, R. R.; Fraser, I. D. C.

10.1101/2019.12.26.888776 — immunology — Posted on 2019-12-26

357 Lactoferrin Reverses Methotrexate Driven Epithelial Barrier Defect by Inhibiting TGF-β Mediated Epithelial to Mesenchymal Transition

Wallach, T.; Srivastava, V.; Reyes, E.; Klein, O. D.; Gartner, Z. J.

10.1101/2019.12.23.878207 — cell biology — Posted on 2019-12-26

358 NFIA regulates granule recruitment and exocytosis in the adult pancreas

Scavuzzo, M. A.; Chmielowiec, J.; Teaw, J.; Yang, D.; Hill, M. C.; Waksmunski, A. R.; Duraine, L.; Camunas-Soler, J.; Dai, X.; King, J. C.; Quake, S. R.; MacDonald, P. E.; Catic, A.; Borowiak, M.

10.1101/2019.12.24.885020 — cell biology — Posted on 2019-12-26

359 Antimetastatic dsRNA mimics identified by live imaging of pathogenic neolymphangiogenesis

Olmeda, D.; Cerezo-Wallis, D.; Calvo, T. G.; Alonso-Curbelo, D.; Canon, E.; Ibartz, N.; Munoz, J.; Ortega, S.; Soengas, M. S.

10.1101/2019.12.26.887943 — cancer biology — Posted on 2019-12-26

360 Single cell transcriptome of CD8+ T cells in multiple cancers reveals comprehensive exhaustion associated mechanisms

Bai, Y.; Chen, Z.; Chen, X.; He, Z.; Long, J.; Du, H.

10.1101/2019.12.26.888503 — cancer biology — Posted on 2019-12-26

361 Genetic analysis of the Arabidopsis TIR1/AFB auxin receptors reveals both overlapping and specialized functions

Prigge, M. J.; Platre, M.; Kadakia, N.; Greenham, K.; Szutu, W.; Pandey, B. K.; Bhosale, R.; Bennett, M. J.; Busch, W.; Estelle, M.

10.1101/529248 — plant biology — Posted on 2019-12-26

362 embarcadero: Species distribution modelling with Bayesian additive regression trees in R

Carlson, C. J.

10.1101/774604 — ecology — Posted on 2019-12-26

363 Graph combinatorics based group-level network inference

Chen, S.; Wu, Q.; Hong, L. E.

10.1101/758490 — neuroscience — Posted on 2019-12-26

364 High Content Screening, a reliable system for Coxiella burnetii isolation from clinical samples

Francis, R.; Mioulane, M.; Le Bideau, M.; Mati, M.-C.; Fournier, P.-E.; Raoult, D.; Bou Khalil, J. Y.; La Scola, B.

10.1101/2019.12.17.880484 — microbiology — Posted on 2019-12-26

365 Transcriptomic analysis of brain hypometabolism links the cholinergic and gingipain hypotheses of Alzheimer's disease pathogenesis

Patel, S.; Howard, D.; Man, A.; Schwartz, D.; Jee, J.; Felsky, D.; Pausova, Z.; Paus, T.; French, L.

10.1101/2019.12.23.887364 — bioinformatics — Posted on 2019-12-26

366 Cortical neuron response selectivity derives from strength in numbers of synapses

Scholl, B.; Thomas, C.; Ryan, M.; Kamasawa, N.; Fitzpatrick, D.

10.1101/2019.12.24.887422 — neuroscience — Posted on 2019-12-26

367 Transcriptomic analysis of brain hypometabolism links the cholinergic and gingipain hypotheses of Alzheimer's disease pathogenesis

Patel, S.; Howard, D.; Man, A.; Schwartz, D.; Jee, J.; Felsky, D.; Pausova, Z.; Paus, T.; French, L.

10.1101/2019.12.23.887364 — bioinformatics — Posted on 2019-12-26

368 Design to Data for mutants of β-glucosidase B from Paenibacillus polymyxa: Q22T, W123R, F155G, Y169M, W438D, V401A

Hou, C.; Smith, P.; Huang, J.; Fell, J. S.; Huang, P.; Vater, A.; Siegel, J. B.

10.1101/2019.12.23.887380 — biochemistry — Posted on 2019-12-26

369 Artiphysiology reveals visual preferences underlying V4-like blur selectivity in a deep convolutional neural network

Entezari Heravi, S.; Bair, W.

10.1101/2019.12.24.886002 — neuroscience — Posted on 2019-12-26

370 A sparse EEG-informed fMRI model for hybrid EEG-fMRI neurofeedback prediction

Cury, C.; Maurel, P.; Gribonval, R.; Barillot, C.

10.1101/599589 — neuroscience — Posted on 2019-12-26

371 The String Decomposition Problem and its Applications to Centromere Assembly

Dvorkina, T.; Bzikadze, A. V.; Pevzner, P. A.

10.1101/2019.12.26.888685 — bioinformatics — Posted on 2019-12-26

372 Overcoming the design, build, test (DBT) bottleneck for synthesis of nonrepetitive protein-RNA binding cassettes for RNA applications

Katz, N.; Tripto, E.; Goldberg, S.; Atar, O.; Yakhini, Z.; Orenstein, Y.; Amit, R.

10.1101/2019.12.24.886168 — synthetic biology — Posted on 2019-12-26

373 Drumming motor sequence training induces myelin remodelling in Huntington's disease: a longitudinal diffusion MRI and quantitative magnetization transfer study

Casella, C.; Bourbon-Teles, J.; Bells, S.; Couthard, E.; Parker, G. D.; Rosser, A.; Jones, D.; Metzler-baddeley, C.

10.1101/2019.12.24.887406 — neuroscience — Posted on 2019-12-26

374 Competition and immune selection of multi-strain Plasmodium falciparum malaria

Gurarie, D.

10.1101/539676 — evolutionary biology — Posted on 2019-12-26

375 Learning improves decoding of odor identity with phase-referenced oscillations in the olfactory bulb

Losacco, J.; Ramirez-Gordillo, D.; Gilmer, J.; Restrepo, D.

10.1101/758813 — neuroscience — Posted on 2019-12-26

376 Prostatic osteopontin expression is associated with symptomatic benign prostatic hyperplasia

Popovics, P.; Awadallah, W. N.; Kohrt, S.; Case, T. C.; Miller, N. L.; Ricke, E.; Huang, W.; Ramirez-Solano, M.; Liu, Q.; Vezina, C. M.; Matusik, R. J.; Ricke, W. A.; Grabowska, M. M.

10.1101/2019.12.23.887612 — pathology — Posted on 2019-12-26

377 Transposon mutagenesis identifies cooperating genetic drivers during keratinocyte transformation and cutaneous squamous cell carcinoma progression

Aiderus, A.; Newberg, J. Y.; Guzman-Rojas, L.; Contreras-Sandoval, A. M.; Meshey, A. L.; Jones, D. J.; Amaya-Manzanares, F.; Rangel, R.; Ward, J. M.; Lee, S. C.; Ban, K. H.-K.; Rogers, K.; Rogers, S. M.; Selvanesan, L.; McNoe, L. A.; Copeland, N. G.; Jenkins, N. A.; Tsai, K. Y.; Black, M. A.; Mann, K. M.; Mann, M. B.

10.1101/2019.12.24.887968 — cancer biology — Posted on 2019-12-26

378 Simultaneous profiling of chromatin accessibility and methylation on human cell lines with nanopore sequencing

Lee, I.; Razaghi, R.; Gilpatrick, T.; Molnar, M.; Sadowski, N.; Simpson, J. T.; Sedlazeck, F. J.; Timp, W.

10.1101/504993 — genomics — Posted on 2019-12-26

379 HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137

Zhang, F.; Bieniasz, P. D. D.

10.1101/2019.12.24.888230 — microbiology — Posted on 2019-12-26

380 Mitochondrial Electron Transport Chain Inhibition Suppresses LPS-Induced Inflammatory Responses via TREM1/STAT3 Pathway in BV2 Microglia

Zhou, C.; Zhang, J.; Ying, W.

10.1101/2019.12.25.888529 — immunology — Posted on 2019-12-26

381 Perturbation of effector and regulatory T cell subsets in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

Karhan, E.; Gunter, C.; Ravanmehr, V.; Horne, M.; Kozhaya, L.; Renzullo, S.; Placek, L.; George, J.; Robinson, P. N.; Vernon, S. D.; Bateman, L.; Unutmaz, D.

10.1101/2019.12.23.887505 — immunology — Posted on 2019-12-26

382 Millefy: visualizing cell-to-cell heterogeneity in read coverage of single-cell RNA sequencing datasets

Ozaki, H.; Hayashi, T.; Umeda, M.; Nikaido, I.

10.1101/537936 — bioinformatics — Posted on 2019-12-26

383 Reclassification of SLC22 Transporters: Analysis of OAT, OCT, OCTN, and other Family Members Reveals 8 Functional Subgroups

Engelhart, D. C.; Granados, J.; Nigam, S. K.; Shi, D.; Saier, M. H.; Baker, M. E.

10.1101/2019.12.23.887299 — pharmacology and toxicology — Posted on 2019-12-26

384 Link Prediction through Deep Generative Model

Wang, X.-W.; Chen, Y.; Liu, Y.-Y.

10.1101/247577 — bioinformatics — Posted on 2019-12-26

385 Meta-analysis of hypoxic transcriptomes from public databases

Bono, H.; Hirota, K.

10.1101/267310 — bioinformatics — Posted on 2019-12-26

386 The Innate Immune Toll-Like Receptor-2 modulates the Depressogenic and Anorexiolytic Neuroinflammatory Response in Obstructive Sleep Apnoea

Polsek, D.; Cash, D.; Veronese, M.; Ilic, K.; Wood, T. C.; Milosevic, M.; Kalanj-Bognar, S.; Morrell, M. J.; Williams, S.; Gajovic, S.; Leschziner, G.; Mitrecic, D.; Rosenzweig, I.

10.1101/2019.12.24.888206 — neuroscience — Posted on 2019-12-26

387 The interplay between host genetics and the gut microbiome reveals common and distinct microbiome features for human complex diseases

Xu, F.; Fu, Y.; Sun, T.-y.; Jiang, Z.; Miao, Z.; Shuai, M.; Gou, W.; Ling, C.-w.; Yang, J.; Wang, J.; Chen, Y.-m.; Zheng, J.-S.

10.1101/2019.12.26.888313 — microbiology — Posted on 2019-12-26

388 Endogenization and excision of human herpesvirus 6 in human genomes

Liu, X.; Kosugi, S.; Koide, R.; Kawamura, Y.; Ito, J.; Miura, H.; Matoba, N.; Matsuzaki, M.; Fujita, M.; Kamada, A. J.; Nakagawa, H.; Tamiya, G.; Matsuda, K.; Murakami, Y.; Kubo, M.; Sato, K.; Momozawa, Y.; Ohashi, J.; Terao, C.; Yoshikawa, T.; Parrish, N. F.; Kamatani, Y.

10.1101/2019.12.19.882522 — genetics — Posted on 2019-12-26

389 Allele frequency spectra in structured populations: Novel-allele probabilities under the labelled coalescent

Uyenoyama, M. K.; Takebayashi, N.; Kumagai, S.

10.1101/2019.12.20.883629 — evolutionary biology — Posted on 2019-12-26

390 RAS mutations drive proliferative chronic myelomonocytic leukemia via activation of a novel KMT2A-PLK1 axis

Carr, R. M.; Vorobyev, D.; Lasho, T.; Marks, D. L.; Tolosa, E. J.; Vedder, A.; Almada, L.; Yurchenko, A.; Padioleau, I.; Alver, B.; Coltro, G.; Binder, M.; Safgren, S. L.; Horn, I.; You, X.; Droin, N.; Solary, E.; Balasis, M. E.; Berger, K.; Pin, C.; Witzig, T.; Buradkar, A.; Graf, T.; Valent, P.; Mangaonkar, A. A.; Robertson, K. D.; Howard, M. T.; Kaufmann, S. H.; Fernandez-Zapico, M. E.; Geissler, K.; Padron, E.; Zhang, J.; Nikolaev, S.; Patnaik, M. M.

10.1101/2019.12.23.874487 — cancer biology — Posted on 2019-12-26

391 VariantStore: A Large-Scale Genomic Variant Search Index

Pandey, P.; Gao, Y.; Kingsford, C.

10.1101/2019.12.24.888297 — bioinformatics — Posted on 2019-12-26

392 Cross-validation of technologies for genotyping CYP2D6 and CYP2C19

Aitchison, K. J.; Carvalho Henriques, B.; Yavorskyy, V.; Wang, Y.; Martens, K.; Behroozi Asl, B.; Carr, M.; Hague, J.; Hu, X.; Maier, W.; Dernovsek, M. Z.; Henigsberg, N.; Souery, D.; Cattaneo, A.; Mors, O.; Rietschel, M.; Lewis, C.; Pfeffer, G.; Bousman, C.

10.1101/2019.12.24.870295 — genetics — Posted on 2019-12-26

393 Experimental copper exposure, but not heat stress, leads to elevated intraovarian thyroid hormone levels

Ruuskanen, S.; Mottola, G.; Anttila, K.

10.1101/717157 — physiology — Posted on 2019-12-26

394 Cooperation of partially-transformed clones: an invisible force behind the early stages of carcinogenesis

Esposito, A.

10.1101/431478 — cancer biology — Posted on 2019-12-26

395 Large scale analyses of genotype-phenotype relationships of glycine decarboxylase mutations and neurological disease severity.

Farris, J.; Calhoun, B.; Alam, M. S.; Lee, S.; Haldar, K.

10.1101/2019.12.20.884080 — bioinformatics — Posted on 2019-12-25

396 Explaining the genetic causality for complex diseases via deep association kernel learning

Bao, F.; Deng, Y.; Du, M.; Ren, Z.; Wan, S.; Xin, J.; Chen, F.; Christiani, D. C.; Wang, M.; Dai, Q.

10.1101/2019.12.17.879866 — bioinformatics — Posted on 2019-12-25

397 Epigenetics of skeletal muscle-associated genes in the ASB, LRRC, TMEM, and OSBPL gene families

Ehrlich, K. C.; Lacey, M.; Ehrlich, M.

10.1101/2019.12.23.887539 — genomics — Posted on 2019-12-25

398 Membrane metalloendopeptidase suppresses prostate carcinogenesis by attenuating effects of gastrin-releasing peptide on stem/progenitor cells

Cheng, C.-Y.; Zhou, Z.; Stone, M.; Lu, B.; Flesken-Nikitin, A.; Nanus, D. M.; Nikitin, A. Y.

10.1101/2019.12.23.887356 — cancer biology — Posted on 2019-12-25

399 Cholinergic circuit genes in the healthy brain are differentially expressed in regions that exhibit gray matter loss in Parkinson's disease

Keo, A.; Dzyubachyk, O.; van der Grond, J.; Hafkemeijer, A.; van de Berg, W. D. J.; van Hilten, J. J.; Reinders, M. J. T.; Mahfouz, A.

10.1101/2019.12.17.875880 — bioinformatics — Posted on 2019-12-25

400 Smash++: an alignment-free and memory-efficient tool to find genomic rearrangements

Hosseini, M.; Pratas, D.; Morgenstern, B.; Pinho, A. J.

10.1101/2019.12.23.887349 — bioinformatics — Posted on 2019-12-25

401 Multimodal DTI-TMS assessment of the motor system in patients with chronic ischemic stroke

Nazarova, M. A.; Kulikova, S. P.; Piradov, M. A.; Limonova, A. S.; Dobrynina, L. A.; Konovalov, R. N.; Novikov, P. A.; Sehm, B.; Villringer, A.; Nikulin, V. V.

10.1101/2019.12.24.886754 — neuroscience — Posted on 2019-12-25

402 Human antimicrobial peptide, LL-37, induces non-inheritable reduced susceptibility to vancomycin in Staphylococcus aureus

Freiberg, C.; Haaber, J.; Vestergaard, M.; Fait, A.; Perrot, V.; Levin, B. R.; Ingmer, H.

10.1101/2019.12.24.886184 — microbiology — Posted on 2019-12-25

403 Killing in response to competition stabilises synthetic microbial consortia

Fedorec, A. J. H.; Karkaria, B. D.; Sulu, M.; Barnes, C. P.

10.1101/2019.12.23.887331 — synthetic biology — Posted on 2019-12-25

404 Analytical solution of linearized equations of the Morris-Lecar neuron model at large constant stimulation

Paraskevov, A. V.; Zemskova, T. S.

10.1101/869875 — neuroscience — Posted on 2019-12-25

405 Machine learning-based detection of insertions and deletions in the human genome

Curnin, C.; Goldfeder, R. L.; Marwaha, S.; Bonner, D.; Waggott, D.; Undiagnosed Diseases Network, ; Wheeler, M. T.; Ashley, E. A.

10.1101/628222 — bioinformatics — Posted on 2019-12-25

406 Structure-based validation can drastically under-estimate error rate in proteome-wide cross-linking mass spectrometry studies

Yugandhar, K.; Wang, T.-Y.; Wierbowski, S. D.; Shayhidin, E. E.; Yu, H.

10.1101/617654 — systems biology — Posted on 2019-12-25

407 Transcriptome analysis of Tartary Buckwheat reveals the differential expression of salt pathway genes

Song, J.-N.; Liu, X.-H.; Wang, Y.-Q.; Yang, H.-B.

10.1101/869263 — genomics — Posted on 2019-12-25

408 Pre-pregnant obesity of mothers in a multi-ethnic cohort is associated with cord blood metabolomic changes in offspring

Alakwaa, F.; Schlueter, R.; Xie, G.; Benny, P.; Gurary, A.; Jia, W.; Chun, S.; Chern, I.; Garmire, L.

10.1101/264374 — epidemiology — Posted on 2019-12-25

409 Modeling microbial metabolic trade-offs in a chemostat

LI, Z.; Liu, B.; Li, S. H.-J.; King, C. G.; Gitai, Z.; Wingreen, N. S.

10.1101/664698 — systems biology — Posted on 2019-12-25

410 Derivation of oligodendrocyte precursor cells from human bone marrow stromal cells and use for re-myelination in the congenitally dysmyelinated brain

Lam, G.; Shea, G. K.-H.; Wu, K. L. K.; Li, M. T.-S.; Kwok, C. H.; Chan, Z. C. K.; Ng, Y.-T.; Wong, W.-P.; Wong, C. Y.; Tsui, A. Y. P.; Shum, D. K. Y.; Chan, Y. S.

10.1101/658997 — neuroscience — Posted on 2019-12-25

411 Readthrough errors purge deleterious cryptic sequences, facilitating the birth of coding sequences

Kosinski, L.; Masel, J.

10.1101/737452 — evolutionary biology — Posted on 2019-12-25

412 The nanophthalmos protein TMEM98 inhibits MYRF self-cleavage and is required for eye size specification

Cross, S. H.; Mckie, L.; Hurd, T. W.; Riley, S.; Wills, J.; Barnard, A. R.; Young, F.; MacLaren, R. E.; Jackson, I. J.

10.1101/2019.12.24.887885 — genetics — Posted on 2019-12-24

413 FilterDCA: interpretable supervised contact prediction using inter-domain coevolution

Muscat, M.; Croce, G.; Sarti, E.; Weigt, M.

10.1101/2019.12.24.887877 — bioinformatics — Posted on 2019-12-24

414 Contrasting model mechanisms of alanine aminotransferase (ALT) release from damaged and necrotic hepatocytes as an example of general biomarker mechanisms

Smith, A. K.; Ropella, G. E. P.; McGill, M. R.; Krishnan, P.; Dutta, L.; Kennedy, R. C.; Jaeschke, H.; Hunt, C. A.

10.1101/2019.12.24.887869 — pharmacology and toxicology — Posted on 2019-12-24

415 Earliest experience of rare but not frequent sounds causes long term changes in the adult auditory cortex

Mehra, M.; Mukesh, A.; Bandyopadhyay, S.

10.1101/2019.12.24.887836 — neuroscience — Posted on 2019-12-24

416 A genome-wide enrichment screen identifies NUMA1-loss as a resistance mechanism against mitotic cell-death induced by BMI1 inhibition

van Lohuizen, M. M. S.; Gisler, S.; Maia, A. R. R.; Chandrasekaran, G.

10.1101/2019.12.24.887851 — cancer biology — Posted on 2019-12-24

417 Mapping the coevolution, leadership and financing of research on viral vectors, RNAi, CRSPR/Cas9 and other genomic editing technologies

Fajardo-Ortiz, D.; Shattuck, A.; Hornbostel, S.

10.1101/2019.12.24.887893 — bioengineering — Posted on 2019-12-24

418 Cell wall O-acetyl and methyl esterification patterns of leaves reflected in atmospheric emission signatures of acetic acid and methanol

Dewhirst, R. A.; Afesth, C. A.; Castanha, C.; Mortimer, J. C.; Jardine, K. J.

10.1101/2019.12.24.887844 — plant biology — Posted on 2019-12-24

419 Vglut2 expression in dopamine neurons contributes to post-lesional striatal reinnervation

Kouwenhoven, W. M.; Fortin, G.; Penttinen, A.-M.; Florence, C.; Delignat-Lavaud, B.; Bourque, M.-J.; Trimbuch, T.; Pereira Luppi, M.; Poulin, J.-F.; Rosenmund, C.; Awatramani, R.; Trudeau, L.-E.

10.1101/2019.12.23.887323 — neuroscience — Posted on 2019-12-24

420 HeiDI: A model for Pavlovian learning and performance with reciprocal associations

Honey, R. C.; Dwyer, D. M.; Iliescu, A. F.

10.1101/2019.12.18.881136 — animal behavior and cognition — Posted on 2019-12-24

421 Unc-4 acts to promote neuronal identity and development of the take-off circuit in the Drosophila CNS

Lacin, H.; Williamson, W. R.; Card, G. M.; Skeath, J. B.; Truman, J. W.

10.1101/2019.12.24.887679 — developmental biology — Posted on 2019-12-24

422 Comment on 'Optimal Policy for Multi-Alternative Decisions'

Marshall, J. A. R.

10.1101/2019.12.18.880872 — animal behavior and cognition — Posted on 2019-12-24

423 Regional astrocyte interferon-γ signaling regulates immunoproteasome-mediated protection during chronic autoimmunity

Smith, B. C.; Sinyuk, M.; Jenkins, J. E.; Psenicka, M. W.; Williams, J. L.

10.1101/2019.12.23.887455 — neuroscience — Posted on 2019-12-24

424 Widespread introgression of the Mus musculus musculus Y chromosome in Central Europe

Macholan, M.; Baird, S. J. E.; Fornuskova, A.; Martincov, I.; Rubik, P.; Dureje, L.; Heitlinger, E.; Pialek, J.

10.1101/2019.12.23.887471 — evolutionary biology — Posted on 2019-12-24

425 The spatial structure of feedforward information in mouse primary visual cortex

Zhuang, J.; Larsen, R. S.; Takasaki, K. T.; Ouellette, N. D.; Daigle, T. L.; Tasic, B. T.; Waters, J.; Zeng, H.; Reid, R. C.

10.1101/2019.12.24.888156 — neuroscience — Posted on 2019-12-24

426 Plasma membrane damage removal by F-actin-mediated shedding from repurposed filopodia

Mageswaran, S. K.; Yang, W. Y.; Chakrabarty, Y.; Oikonomou, C. M.; Jensen, G. J.

10.1101/2019.12.23.887638 — cell biology — Posted on 2019-12-24

427 The interaction between non-fusogenic Sec22b-Stx complexes and Extended-Synaptotagmins promotes neurite growth and ramification

Gallo, A.; Danglot, L.; Giordano, F.; Binz, T.; Vannier, C.; GALLI, T.

10.1101/2019.12.24.886648 — cell biology — Posted on 2019-12-24

428 Neural circuit mechanism for generating categorical representations

Mahajan, N. R.; Mysore, S. P.

10.1101/2019.12.24.887810 — neuroscience — Posted on 2019-12-24

429 A perinuclear microtubule-organizing center controls nuclear positioning and basement membrane secretion

Zheng, Y.; Buchwalter, R. A.; Zheng, C.; Wight, E. M.; Chen, J. V.; Megraw, T. L.

10.1101/2019.12.24.888065 — cell biology — Posted on 2019-12-24

430 Spatiotemporal dynamics of multi-vesicular release is determined by heterogeneity of release sites within central synapses

Maschi, D.; Klyachko, V.

10.1101/2019.12.23.887372 — neuroscience — Posted on 2019-12-24

431 Topographic functional interactions between caudate and cortex are organized by network and degrade with age

O'Rawe, J. F.; Leung, H.-C.

10.1101/2019.12.23.887398 — neuroscience — Posted on 2019-12-24

432 Drumming motor sequence training induces myelin remodelling in Huntington's disease: a longitudinal diffusion MRI and quantitative magnetization transfer study

Casella, C.; Bourbon-Teles, J.; Bells, S.; Couthard, E.; Rosser, A.; Jones, D.; Metzler-baddeley, C.

10.1101/2019.12.24.887406 — neuroscience — Posted on 2019-12-24

433 Structure of the Glutamate-Like Receptor GLR3.2 ligand-binding domain

Gangwar, S. P.; Green, M.; Sobolevsky, A.

10.1101/2019.12.23.887497 — biophysics — Posted on 2019-12-24

434 Reconstructing the Evolutionary History of Nitrogenases: Evidence for Ancestral Molybdenum-Cofactor Utilization

Garcia, A. K.; McShea, H.; Kolaczkowski, B.; Kacar, B.

10.1101/714469 — evolutionary biology — Posted on 2019-12-24

435 Determining organ weight toxicity with Bayesian causal models: Improving on the analysis of relative organ weights

Lazic, S. E.; Semenova, E.; Williams, D.

10.1101/754853 — pharmacology and toxicology — Posted on 2019-12-24

436 Bayesian transfer in a complex spatial localisation task

Kiryakova, R.; Aston, S.; Beierholm, U.; Nardini, M.

10.1101/716431 — neuroscience — Posted on 2019-12-24

437 A Multi-Niche Microvascularized Human Bone-Marrow-on-a-Chip

Nelson, M. R.; Ghoshal, D.; Mejias, J. C.; Frey Rubio, D.; Keith, E.; Roy, K.

10.1101/2019.12.15.876813 — bioengineering — Posted on 2019-12-24

438 Nanopore sequencing reveals U2AF1 S34F-associated full-length isoforms

Soulette, C. M.; Hrabeta-Robinson, E.; Tang, A.; Marin, M. G.; Brooks, A. N.

10.1101/871863 — genomics — Posted on 2019-12-24

439 functionInk: An efficient method to detect functional groups in multidimensional networks reveals the hidden structure of ecological communities

Pascual-Garcia, A.; Bell, T.

10.1101/656504 — ecology — Posted on 2019-12-24

440 Acetyl-CoA production by select metabolic pathways promotes cardiac repair after myocardial infarction via mediating histone acetylation

Lei, I.; Tian, S.; Gao, W.; Liu, L.; Guo, Y.; Wang, Z.

10.1101/622746 — cell biology — Posted on 2019-12-24

441 A geometric characterization of population coding in the prefrontal cortex and hippocampus during a paired-associate learning task

Liu, Y.; Brincat, S. L.; Miller, E. K.; Hasselmo, M. E.

10.1101/578849 — neuroscience — Posted on 2019-12-24

442 An RNA degradation complex required for silencing of Polycomb target genes

Zhou, H.; Shipkovenska, G.; Kalocsay, M.; Zhang, J.; Luo, Z.; Moazed, D.

10.1101/2019.12.23.887547 — molecular biology — Posted on 2019-12-24

443 CeutaOPEN: Individual-based field observations of breeding snowy plovers Charadrius nivosus

Eberhart-Phillips, L. J.; Cruz-Lopez, M.; Lozano-Angulo, L.; Gomez del Angel, S.; Rojas-Abreu, W.; Küpper, C.

10.1101/2019.12.20.884825 — ecology — Posted on 2019-12-24

444 Reactomics: Using mass spectrometry as a chemical reaction detector

Yu, M.; Petrick, L.

10.1101/855148 — bioinformatics — Posted on 2019-12-24

445 BACH family members regulate angiogenesis and lymphangiogenesis by modulating VEGFC expression

Cohen, B.; Tempelhof, H.; Raz, T.; Oren, R.; Nicenboim, J.; Bochner, F.; Even, R.; Jelinski, A.; Eilam, R.; Ben-Dor, S.; Addadi, Y.; Golani, O.; Lazar, S.; Yaniv, K.; Neeman, M.

10.1101/2019.12.13.876268 — developmental biology — Posted on 2019-12-24

446 The Eruca sativa genome and transcriptome: A targeted analysis of sulfur metabolism and glucosinolate biosynthesis pre and postharvest

Bell, L.; Chadwick, M.; Puranik, M.; Tudor, R.; Methven, L.; Kennedy, S.; Wagstaff, C.

10.1101/2019.12.23.886937 — plant biology — Posted on 2019-12-24

447 Highly efficient homology-directed repair using transient CRISPR/Cpf1-geminiviral replicon in tomato

Vu, T. V.; Sivankalyani, V.; Kim, E.-J.; Doan, D. T. H.; Tran, M. T.; Kim, J.; Sung, Y. W.; Park, M.; Kang, Y. J.; Kim, J.-Y.

10.1101/521419 — synthetic biology — Posted on 2019-12-24

448 Nonparametric Anomaly Detection on Time Series of Graphs

Ofori-Boateng, D.; Gel, Y.; Cribben, I.

10.1101/2019.12.15.876730 — neuroscience — Posted on 2019-12-24

449 Maximum Likelihood Reconstruction of Ancestral Networks by Integer Linear Programming

Rajan, V.; Kingsford, C.; Zhang, X.

10.1101/574814 — bioinformatics — Posted on 2019-12-24

450 Phytoplankton consortia as a blueprint for mutually beneficial eukaryote-bacteria ecosystems: Biocoenosis of Botryococcus consortia

Blifernez-Klassen, O.; Klassen, V.; Wibberg, D.; Cebeci, E.; Henke, C.; Rueckert, C.; Chaudhari, S.; Rupp, O.; Blom, J.; Winkler, A.; Al-Dilaimi, A.; Goesmann, A.; Sczyrba, A.; Kalinowski, J.; Braeutigam, A.; Kruse, O.

10.1101/476887 — ecology — Posted on 2019-12-24

451 Polychromatic solar energy conversion in pigment-protein chimeras that unite the two kingdoms of (bacterio)chlorophyll-based photosynthesis

Liu, J.; Friebe, V. M.; Frese, R. N.; Jones, M. R.

10.1101/565283 — synthetic biology — Posted on 2019-12-24

452 Separability and Geometry of Object Manifolds in Deep Neural Networks

Cohen, U.; Chung, S.; Lee, D. D.; Sompolinsky, H.

10.1101/644658 — neuroscience — Posted on 2019-12-24

453 Temporal discounting correlates with directed exploration but not with random exploration

Sadeghiyeh, H.; Wang, S.; Alberhasky, M. R.; Kyllo, H. M.; Shenhav, A.; Wilson, R. C.

10.1101/783498 — neuroscience — Posted on 2019-12-24

454 Deficiency of Norepinephrine Transmission In Brain Contributed To Seizure-Induced Respiratory Arrest In the DBA/1 Mouse SUDEP Model

Shen, Y.; MA, H.; Lu, H.; Zhao, H.; Sun, J.; Cheng, Y.; Shen, Y.; Zhou, Y. D.; Zhang, H.

10.1101/865691 — neuroscience — Posted on 2019-12-24

455 Where can a place cell put its fields? Let us count the ways.

Yim, M. Y.; Sadun, L. A.; Fiete, I. R.; Taillefumier, T.

10.1101/2019.12.19.881458 — neuroscience — Posted on 2019-12-24

456 Human neutrophils produce antifungal extracellular vesicles against Aspergillus fumigatus

Shopova, I. A.; Belyaev, I.; Dasari, P.; Jahreis, S.; Stroe, M. C.; Cseresnyes, Z.; Zimmermann, A.-K.; Medyukhina, A.; Svensson, C.-M.; Krueger, T.; Szeifert, V.; Nietzsche, S.; Conrad, T.; Blango, M. G.; Kniemeyer, O.; von Lilienfeld-Toal, M.; Zipfel, P.; Ligeti, E.; Figge, M. T.; Brakhage, A. A.

10.1101/620294 — microbiology — Posted on 2019-12-24

457 Treg cells maintain selective access to IL-2 and immune homeostasis despite substantially reduced CD25 function

Hayes, E. T.; Hagan, C. E.; Campbell, D. J.

10.1101/786228 — immunology — Posted on 2019-12-24

458 Plasma FABP4 is associated with liver disease recovery during treatment-induced clearance of chronic HCV infection

Gorin, J.-B.; Malone, D. F. G.; Strunz, B.; Carlsson, T.; Aleman, S.; Björkström, N. K.; Falconer, K.; Sandberg, J. K.

10.1101/698217 — immunology — Posted on 2019-12-24

459 A neuronal thermostat controls membrane fluidity in C. elegans

Chauve, L.; Murdoch, S.; Masoudzadeh, F.; Hodge, F.; Lopez-Clavijo, A.; Okkenhaug, H.; Kleigrewe, K.; Wingett, S.; West, G.; Wakelam, M.; Casanueva, O.

10.1101/2019.12.20.882514 — genetics — Posted on 2019-12-24

460 A Genetic Screen Links the Disease-Associated Nab2 RNA-Binding Protein to the Planar Cell Polarity Pathway in Drosophila melanogaster

Lee, W.-H.; Corgiat, E. B.; Rounds, J. C.; Shepherd, Z.; Corbett, A. H.; Moberg, K.

10.1101/2019.12.23.887257 — developmental biology — Posted on 2019-12-24

461 Prohibitin depletion extends lifespan of a TORC2/SGK-1 mutant through autophagy

Hernando-Rodriguez, B.; Perez-Jimenez, M. M.; Rodriguez-Palero, M. J.; Pla, A.; Martinez-Bueno, M. D.; de la Cruz Ruiz, P.; Gatsi, R.; Artal-Sanz, M.

10.1101/792465 — cell biology — Posted on 2019-12-24

462 Dual-stage-processed 3D network super-resolution for volumetric fluorescence microscopy far beyond throughput limit

Zhang, H.; Zhao, Y.; Fang, C.; Li, G.; Li, Y.; Zhang, M.; Li, Y.; Wan, P.; Yu, T.; Zhang, Y.; Zhu, D.; Gao, S.; Fei, P.

10.1101/435040 — biophysics — Posted on 2019-12-24

463 Premature termination codons signal targeted gene repair by nonsense-mediated gene editing in E. coli

Wang, X.; Wang, X.; Peng, H.; Li, C.; Wang, Y.; Chen, G.; Zhang, J.

10.1101/069971 — genetics — Posted on 2019-12-24

464 Soil solution in Swiss forest stands: a 20 year's time series

Braun, S.

10.1101/2019.12.23.887042 — ecology — Posted on 2019-12-23

465 Handling and Packaging of Medical Bags at the Acute Disaster Site Under High Temperature Conditions

Ando, W.; Imamura, Y.; Nagashima, H.; Kondo, K.; Nakamura, K.; Otori, K.

10.1101/2019.12.23.887000 — scientific communication and education — Posted on 2019-12-23

466 Morphologically and physiologically diverse fruits of two Lepidium species differ in allocation of glucosinolates into immature and mature seed and pericarp

Mohammed, S.; Bhattacharya, S.; Gesing, M. A.; Klupsch, K.; Theissen, G.; Mummenhoff, K.; Müller, C.

10.1101/2019.12.23.887026 — plant biology — Posted on 2019-12-23

467 Leptin signaling and the intervertebral disc: Sex dependent effects of leptin receptor deficiency and Western diet on the spine in a type 2 diabetes mouse model

Natelson, D. M.; Lai, A.; Krishnamoorthy, D.; Hoy, R. C.; Iatridis, J. C.; Illien-Junger, S.

10.1101/2019.12.23.887018 — physiology — Posted on 2019-12-23

468 An in vitro quantitative systems pharmacology approach for deconvolving mechanisms of drug-induced, multilineage cytopenias

Wilson, J.; Lu, D.; Corr, N.; Fullerton, A.; Lu, J.

10.1101/2019.12.23.886960 — pharmacology and toxicology — Posted on 2019-12-23

469 Haplotype of the astrocytic water channel AQP4 modulates slow wave energy in human NREM sleep

Ulv Larsen, S. M.; Landolt, H.-P.; Berger, W.; Nedergaard, M.; Knudsen, G. M.; Holst, S. C.

10.1101/2019.12.23.886952 — neuroscience — Posted on 2019-12-23

470 A Cell Penetrating Peptide from Type I Interferon Protects the Retina in a Mouse Model of Autoimmune Uveitis

Ahmed, C. M.; Ildefonso, C. J.; Johnson, H. M.; Lewin, A. S.

10.1101/2019.12.23.886986 — immunology — Posted on 2019-12-23

471 Phylogenomics supports a Cenozoic rediversification of the "living fossil" Isoetes

Wood, D.; Besnard, G.; Beerling, D. J.; Osborne, C. P.; Christin, P.-A.

10.1101/2019.12.23.886994 — evolutionary biology — Posted on 2019-12-23

472 Rift Valley fever in northern Senegal : a modelling approach to analyse the processes underlying virus circulation recurrence

Durand, B.; Lo Modou, M.; Tran, A.; Ba, A.; Sow, F.; Belkhiria, J.; Fall, A. G.; Biteye, B.; Grosbois, V.; Chevalier, V.

10.1101/2019.12.23.886978 — ecology — Posted on 2019-12-23

473 Expression and function of voltage gated proton channels (H V 1) in MDA-MB-231 cells

Bare, D.; Cherny, V.; Abukhdeir, A.; DeCoursey, T.; morgan, d.

10.1101/2019.12.23.886945 — cell biology — Posted on 2019-12-23

474 Genome sequencing and functional characterization of a Dictyopanus pusillus fungal extract offers a promising alternative for lignocellulose pretreatment of oil palm residues

Rueda, A. M.; Lopez de los Santos, Y.; Vincent, A. T.; Letourneau, M.; Hernandez, I.; Sanchez, C. I.; Molina, D.; Ospina, S. A.; Veyrier, F. J.; Doucet, N.

10.1101/2019.12.23.887034 — bioengineering — Posted on 2019-12-23

475 Regionally divergent drivers of historical diversification in the late Quaternary in a widely distributed generalist species, the common pheasant Phasianus colchicus

Liu, S.; Liu, Y.; Jelen, E.; Alibadian, M.; Yao, C.-t.; Li, X.; Kayvanfar, N.; Wang, Y.; Vahidi, F.; Han, J.; Sundev, G.; Zhang, Z.; Schweizer, M.

10.1101/2019.12.21.881813 — evolutionary biology — Posted on 2019-12-23

476 Molecular Basis for the Evolved Instability of a Human G-Protein Coupled Receptor

Chamness, L. M.; Zelt, N. B.; Kuntz, C. P.; Bender, B. J.; Penn, W. D.; Ziarek, J. J.; Meiler, J. P.; Schlebach, J. P.

10.1101/2019.12.20.884718 — biochemistry — Posted on 2019-12-23

477 TrkB agonists prevent post-ischemic BDNF-TrkB mediated emergence of refractory neonatal seizures in CD-1 pups.

Kipnis, P. A.; Sullivan, B. J.; Carter, B. M.; Kadam, S. D.

10.1101/2019.12.23.887190 — neuroscience — Posted on 2019-12-23

478 Non-destructive enzymatic deamination enables single molecule long read sequencing for the determination of 5-methylcytosine and 5-hydroxymethylcytosine at single base resolution.

Sun, Z.; Vaisvila, R.; Yan, B.; Baum, c.; Saleh, L.; Samaranayake, M.; Guan, S.; Dai, N.; Correa, I. R.; Pradhan, S.; Davis, T. B.; Evans, T. C.; Ettwiller, L.

10.1101/2019.12.20.885061 — genomics — Posted on 2019-12-23

479 The dynamics of oligodendrocyte generation: how distinct is the mouse from the human?

Gonsalvez, D. G.; Craig, G. A.; Walsh, D. M.; Hughes, B. D.; Wood, R. J.; Yoo, S. W.; Murray, S. S.; Xiao, J.

10.1101/2019.12.23.887174 — neuroscience — Posted on 2019-12-23

480 A cellular stress response induced by the CRISPR/dCas9 activation system is not heritable through cell divisions

Johnston, A. D.; Abdulrazak, A.; Sato, H.; Maqbool, S.; Suzuki, M.; Greally, J. M.; Simoes-Pires, C. A.

10.1101/2019.12.23.887224 — genetics — Posted on 2019-12-23

481 A novel mouse model expressing human forms for complement receptors CR1 and CR2

Jackson, H.; Foley, K.; O'Rourke, R.; Stearns, T.; Fathalla, D.; Morgan, P.; Howell, G.

10.1101/2019.12.23.887489 — genetics — Posted on 2019-12-23

482 Evolutionary rescue and drug resistance on multicopy plasmids

Santer, M.; Uecker, H.

10.1101/2019.12.23.887315 — evolutionary biology — Posted on 2019-12-23

483 Two distinct bacterial biofilm components trigger metamorphosis in the colonial hydrozoan Hydractinia echinata

Guo, H.; Rischer, M.; Westermann, M.; Beemelmanns, C.

10.1101/2019.12.23.887182 — ecology — Posted on 2019-12-23

484 A single cell transcriptional atlas of early synovial joint development

Bian, Q.; Cheng, Y.-H.; Wilson, J. P.; Kim, D. W.; Wang, H.; Blackshaw, S.; Cahan, P.

10.1101/2019.12.23.887208 — developmental biology — Posted on 2019-12-23

485 Statistical physics of interacting proteins: impact of dataset size and quality assessed in synthetic sequences

Gandarilla-Perez, C. A.; Mergny, P.; Weigt, M.; Bitbol, A.-F.

10.1101/2019.12.23.887307 — bioinformatics — Posted on 2019-12-23

486 Transfer from number to size reveals abstract coding of magnitude in honeybees

Bortot, M.; Stancher, G.; Vallortigara, G.

10.1101/2019.12.23.887281 — animal behavior and cognition — Posted on 2019-12-23

487 Model balancing: consistent in-vivo kinetic constants and metabolic states obtained by convex optimisation

Liebermeister, W.

10.1101/2019.12.23.887166 — systems biology — Posted on 2019-12-23

488 The Lands cycle modulates plasma membrane lipid organization and insulin sensitivity in skeletal muscle

Ferrara, P. J.; Rong, X.; Maschek, J. A.; Verkerke, A. R.; Siripoksup, P.; Song, H.; Krishnan, K. C.; Johnson, J. M.; Turk, J.; Houmard, J. A.; Lusis, A. J.; Cox, J. E.; Shaikh, S. R.; Tontonoz, P.; Funai, K.

10.1101/2019.12.23.887232 — physiology — Posted on 2019-12-23

489 A Metric Space of Ranked Tree Shapes and Ranked Genealogies

Kim, J.; Rosenberg, N. A.; Palacios, J. A.

10.1101/2019.12.23.887125 — evolutionary biology — Posted on 2019-12-23

490 TandemMapper and TandemQUAST: mapping long reads and assessing/improving assembly quality in extra-long tandem repeats

Mikheenko, A.; Bzikadze, A. V.; Gurevich, A.; Miga, K. H.; Pevzner, P. A.

10.1101/2019.12.23.887158 — bioinformatics — Posted on 2019-12-23

491 The Eruca sativa genome and transcriptome: A targeted analysis of sulfur metabolism and glucosinolate biosynthesis pre and postharvest

Bell, L.; Chadwick, M.; Puranik, M.; Tudor, R.; Methven, L.; Kennedy, S.; Wagstaff, C.

10.1101/2019.12.23.886937 — plant biology — Posted on 2019-12-23

492 Effect of oral administration of 1,3-1,6 β-glucans in DWV naturally infected newly emerged bees (Apis mellifera L.)

Felicioli, A.; Forzan, M.; Sagona, S.; D'Agostino, P.; Baido, D.; Fronte, B.; Mazzei, M.

10.1101/2019.12.23.887091 — microbiology — Posted on 2019-12-23

493 Lipin-1 contributes to IL-4 mediated macrophage polarization

Chandra, S.; Schilke, R. M.; Blackburn, C. M. R.; Yurochko, A.; Mirza, R.; Scott, R. S.; Finck, B. N.; Woolard, M. D.

10.1101/2019.12.23.887109 — immunology — Posted on 2019-12-23

494 Systematic analysis of 1,298 RNA-Seq samples and construction of a comprehensive soybean (Glycine max) expression atlas

Machado, F. B.; Moharana, K. C.; Almeida-Silva, F.; Gazara, R. K.; Pedrosa-Silva, F.; Coelho, F. S.; Grativol, C.; Venancio, T. M.

10.1101/2019.12.23.886853 — plant biology — Posted on 2019-12-23

495 Flavodiiron proteins and NDH-1 cooperate to maintain photosynthetic redox poise in Synechocystis

Nikkanen, L. E.; Santana Sanchez, A. I.; Ermakova, M.; Rogner, M.; Cournac, L.; Allahverdiyeva, Y.

10.1101/2019.12.23.886929 — plant biology — Posted on 2019-12-23

496 Individual head models for estimating the TMS-induced electric field in rat brain

Koponen, L. M.; Stenroos, M.; Nieminen, J. O.; Jokivarsi, K.; Grohn, O.; Ilmoniemi, R. J.

10.1101/2019.12.23.886861 — neuroscience — Posted on 2019-12-23

497 Heterogeneous habenular neuronal ensembles during selection of defensive behaviors

Lecca, S.; Namboodiri, V.; Restivo, L.; Gervasi, N.; Pillolla, G.; Stuber, G.; Mameli, M.

10.1101/2019.12.22.886457 — neuroscience — Posted on 2019-12-23

498 Listeriolysin O promotes the intravacuolar growth of Listeria monocytogenes in epithelial cells

Peron Cane, C.; Leblanc, J.; Wingertsmann, L.; Fernandez, J. C.; Gautier, A.; Desprat, N.; Lebreton, A.

10.1101/2019.12.23.886689 — microbiology — Posted on 2019-12-23

499 Cross-Species Integration of Transcriptomic Effects of Tobacco and Nicotine Exposure Helps to Prioritize Genetic Effects on Human Tobacco Consumption

Palmer, R. H. C.; Benca-Bachman, C. E.; Bubier, J. A.; McGeary, J. E.; Ramgiri, N.; Srijeyanthan, J.; Huggett, S.; Yang, J.; Visscher, P. M.; Yang, J. M.; Knopik, V. S.; Chesler, E.

10.1101/2019.12.23.887083 — genetics — Posted on 2019-12-23

500 Drosophila PDGF/VEGF signaling from muscles to hepatocyte-like cells protects against obesity

Ghosh, A. C.; Perrimon, N.

10.1101/2019.12.23.887059 — genetics — Posted on 2019-12-23

501 Environmental unpredictability shapes glucocorticoid regulation across populations of tree swallows

Zimmer, C.; Taff, C. C.; Ardia, D. R.; Rose, A. P.; Aborn, D. A.; Johnson, S. L.; Vitousek, M. N.

10.1101/2019.12.23.887075 — evolutionary biology — Posted on 2019-12-23

502 GCNG: Graph convolutional networks for inferring cell-cell interactions

Yuan, Y.; Bar-Joseph, Z.

10.1101/2019.12.23.887133 — bioinformatics — Posted on 2019-12-23

503 PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response

Ye, J.; Huang, A.; Wang, H.; Zhang, A. M. Y.; Huang, X.; Lan, Q.; Sato, T.; Goyama, S.; Kurokawa, M.; Deng, C.; Sander, M.; Schaeffer, D. F.; Li, W.; Kopp, J. L.; Xie, R.

10.1101/2019.12.18.880823 — cancer biology — Posted on 2019-12-23

504 Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases

Ritchie, S. C.; Liu, Y.; Lambert, S. A.; Teo, S. M.; Scepanovic, P.; Marten, J.; Zahid, S.; Chaffin, M.; Abraham, G.; Ouwehand, W. H.; Roberts, D. J.; Watkins, N. A.; Di Angelantonio, E.; Soranzo, N.; Burgess, S.; Drew, B. G.; Kathiresan, S.; Calkin, A.; Khera, A. V.; Danesh, J.; Butterworth, A. S.; Inouye, M.

10.1101/2019.12.14.876474 — genetics — Posted on 2019-12-23

505 PSF broadening due to fluorescence emission

Becker, J.; Heintzmann, R.

10.1101/2019.12.21.885707 — biophysics — Posted on 2019-12-23

506 Medicago truncatula Yellow Stripe1-Like3 gene is involved in symbiotic nitrogen fixation

Castro-Rodriguez, R.; Abreu, I.; Reguera, M.; Novoa-Aponte, L.; Mijovilovich, A.; Jimenez-Pastor, F. J.; Abadia, J.; Wen, J.; Mysore, K.; Alvarez-Fernandez, A.; Küpper, H.; Imperial, J.; Gonzalez-Guerrero, M.

10.1101/2019.12.23.887448 — plant biology — Posted on 2019-12-23

507 Germline de novo mutation rates on exons versus introns in humans

Rodriguez-Galindo, M.; Casillas, S.; Weghorn, D.; Barbadilla, A.

10.1101/2019.12.23.886879 — evolutionary biology — Posted on 2019-12-23

508 Prohibitin depletion extends lifespan of a TORC2/SGK-1 mutant by suppressing membrane lipid defects

Hernando-Rodriguez, B.; Perez-Jimenez, M. M.; Rodriguez-Palero, M. J.; Pla, A.; Martinez-Bueno, M. D.; de la Cruz Ruiz, P.; Gatsi, R.; Artal-Sanz, M.

10.1101/792465 — cell biology — Posted on 2019-12-23

509 A spatio-temporal mathematical model for the dynamics of paclitaxel in cell monolayers.

Proudfoot, I.; Epemolu, O.; Vallardi, G.; Ptashnyk, M.; Saurin, A. T.; Murray, P. J.; Shishikura, Y.

10.1101/2019.12.12.874032 — cancer biology — Posted on 2019-12-23

510 Simulating intervertebral disc cell behavior within 3D multifactorial environments

Baumgartner, L.; Reagh, J. J.; Gonzalez Ballester, M. A.; Noailly, J.

10.1101/2019.12.23.886887 — systems biology — Posted on 2019-12-23

511 Anesthetic agents affect urodynamic parameters and anesthetic depth at doses necessary to facilitate preclinical testing in felines

Xu, J. J.; Yousuf, Z.; Ouyang, Z.; Kennedy, E.; Lester, P.; Martin, T.; Bruns, T.

10.1101/868398 — physiology — Posted on 2019-12-23

512 Microglial homeostasis requires balanced CSF-1/CSF-2 receptor signaling

Chitu, V.; Biundo, F.; Shlager, G. G. L.; Park, E. S.; Wang, P.; Gulinello, M. E.; Gokhan, S.; Ketchum, H. C.; Saha, K.; DeTure, M. A.; Dickson, D. W.; Wszolek, Z. K.; Zheng, D.; Croxford, A. L.; Becher, B.; Sun, D.; Mehler, M. F.; Stanley, E. R.

10.1101/2019.12.23.885186 — neuroscience — Posted on 2019-12-23

513 Dopamine manipulations modulate paranoid social inferences in healthy people.

Barnby, J. M.; Bell, V.; Deeley, Q.; Mehta, M. A.

10.1101/2019.12.18.874255 — neuroscience — Posted on 2019-12-23

514 First isolation and characterisation of Alongshan virus in Russia

Kholodilov, I. S.; Litov, A. G.; Klimentov, A. S.; Belova, O. A.; Polienko, A. E.; Nikitin, N. A.; Shchetinin, A. M.; Ivannikova, A. Y.; Bell-Sakyi, L.; Yakovlev, A. S.; Bugmyrin, S. V.; Bespyatova, L. A.; Gmyl, L. V.; Luchinina, S. V.; Gmyl, A. P.; Gushchin, V. A.; Karganova, G. G.

10.1101/862573 — molecular biology — Posted on 2019-12-23

515 Competitive Inhibition of Cortisol by Prostaglandins at the Ligand Binding Domain of Glucocorticoid Receptors

Schaper, C.

10.1101/851501 — molecular biology — Posted on 2019-12-23

516 Topologically Dependent Abundance of Spontaneous DNA Damage in Single Human Cells

Zhu, Q.; Niu, Y.; Gundry, M.; Sheng, K.; Niu, M.; Zong, C.

10.1101/859686 — genomics — Posted on 2019-12-23

517 The genome of the zoonotic malaria parasite Plasmodium simium reveals adaptations to host-switching

Mourier, T.; de Alvarenga, D. A. M.; Kaushik, A.; de Pina-Costa, A.; Guzman-Vega, F. J.; Douvropoulou, O.; Guan, Q.; Forrester, S.; de Abreu, F. V. S.; Junior, C. B.; Junior, J. C. d. S.; Hirano, Z. M. B.; Pissinatti, A.; Moreira, S. B.; Ferreira-da-Cruz, M. d. F.; de Oliveira, R. L.; Arold, S. T.; Jeffares, D. C.; Brasil, P.; de Brito, C. F. A.; Culleton, R.; Daniel-Ribeiro, C. T.; Pain, A.

10.1101/841171 — genomics — Posted on 2019-12-23

518 CellCountCV - a web-application for accurate cell counting and automated batch processing of microscopy images using fully-convolutional neural networks

Antonets, D. V.; Russkikh, N. E.; Sanchez, A.; Kovalenko, V. R.; Bairamova, E. M.; Shtokalo, D. N.; Medvedev, S. P.; Zakian, S. M.

10.1101/867218 — cell biology — Posted on 2019-12-23

519 Inhibiting xCT/SLC7A11 induces ferroptosis of myofibroblastic hepatic stellate cells and protects against liver fibrosis

Du, K.; Oh, S.-H.; Sun, T.; Yang, W.-H.; Chi, J.-T. A.; Diehl, A. M.

10.1101/2019.12.23.886259 — cell biology — Posted on 2019-12-23

520 Expression and function of voltage gated proton channels (H V 1) in MDA-MB-231 cells

Bare, D.; Cherny, V.; Abukhdeir, A.; DeCoursey, T.; morgan, d.

10.1101/2019.12.23.886945 — cell biology — Posted on 2019-12-23

521 The Glyco-enzyme adaptor GOLPH3 Links Intra-Golgi Transport Dynamics to Glycosylation Patterns and Cell Proliferation

Rizzo, R.; Russo, D.; Kurokawa, K.; Sahu, P.; Lombardi, B.; Supino, D.; Zhukovsky, M.; Vocat, A.; Pothukuchi, P.; Kunnathully, V.; Capolupo, L.; Boncompain, G.; Vitagliano, C.; Zito Marino, F.; Aquino, G.; Montariello, D.; Henklein, P.; Mandrich, L.; Botti, G.; Clausen, H.; Mandel, U.; Yamaji, T.; Hanada, K.; Budillon, A.; Perez, F.; Parashuraman, S.; Hannun, Y. A.; Nakano, A.; Corda, D.; D'Angelo, G.; Luini, A.

10.1101/870477 — cell biology — Posted on 2019-12-23

522 Acute exposure to nicotine vapor causes short-term increases in impulsive choice in rats.

Flores, R. J.; Alshbool, F. Z.; Giner, P.; O'Dell, L. E.; Mendez, I. A.

10.1101/842005 — animal behavior and cognition — Posted on 2019-12-23

523 A High-Throughput Extraction and Analysis Method for Steroidal Glycoalkaloids in Tomato

Dzakovich, M. P.; Hartman, J. L.; Cooperstone, J. L.

10.1101/2019.12.23.878223 — plant biology — Posted on 2019-12-23

524 Optimal number and placement of EEG electrodes for measurement of neural tracking of speech

Montoya Martinez, J.; Bertrand, A.; Francart, T.

10.1101/800979 — neuroscience — Posted on 2019-12-23

525 Genetic analysis of Aedes aegypti captured in two international airports serving the Greater Tokyo area during 2012-2015

Itokawa, K.; Hu, J.; Sukehiro, N.; Tsuda, Y.; Komagata, O.; Kasai, S.; Tomita, T.; Minakawa, N.; Sawabe, K.

10.1101/823138 — genetics — Posted on 2019-12-23

526 A Genetic Screen Links the Disease-Associated Nab2 RNA-Binding Protein to the Planar Cell Polarity Pathway in Drosophila melanogaster

Moberg, K.; Lee, W.-H.; Corbett, A. H.; Corgiat, E. B.; Rounds, J. C.; Shepherd, Z.

10.1101/2019.12.23.887257 — developmental biology — Posted on 2019-12-23

527 Interleukin-33 promotes type 1 cytokine expression via p38 MAPK in human natural killer cells

Ohayon, D. E.; Ali, A.; Alarcon, P. C.; Krishnamurthy, D.; Kottyan, L.; Borchers, M.; Waggoner, S. N.

10.1101/777847 — immunology — Posted on 2019-12-23

528 Global Analysis of Human mRNA Folding Disruptions in Synonymous Variants Demonstrates Significant Population Constraint

Gaither, J. B. S.; Lammi, G. E.; Li, J. L.; Gordon, D. M.; Kuck, H. C.; Kelly, B. J.; Fitch, J. R.; White, P.

10.1101/712679 — genomics — Posted on 2019-12-23

529 Acid and inflammatory sensitisation of naked mole-rat colonic afferent nerves

Hockley, J. R.; Barker, K. H.; Taylor, T. S.; Callejo, G.; Husson, Z. M.; Bulmer, D. C.; Smith, E. S. J.

10.1101/636571 — neuroscience — Posted on 2019-12-23

530 An uncertainty principle for neural coding: Conjugate representations of position and velocity are mapped onto firing rates and co-firing rates of neural spike trains

Grgurich, R.; Blair, H. T.

10.1101/743310 — neuroscience — Posted on 2019-12-23

531 Differential side-effects of Bacillus thuringiensis bioinsecticide on non-target Drosophila flies

Babin, A.; Nawrot-Esposito, M.-P.; Gallet, A.; Gatti, J.-L.; Poirie, M.

10.1101/541847 — ecology — Posted on 2019-12-23

532 DeepTCR: a deep learning framework for understanding T-cell receptor sequence signatures within complex T-cell repertoires

Sidhom, J.-W.; Larman, H. B.; Ross-MacDonald, P.; Wind-Rotolo, M.; Pardoll, D. M.; Baras, A. S.

10.1101/464107 — bioinformatics — Posted on 2019-12-23

533 A very fast time scale of human motor adaptation: within movement adjustments of internal representations during reaching

Crevecoeur, F.; Thonnard, J.-L.; Lefevre, P.

10.1101/269134 — neuroscience — Posted on 2019-12-23

534 Adventures in Multi-Omics I: Combining heterogeneous data sets via relationships matrices

Akdemir, D.; Isidro Sanchez, J.

10.1101/857425 — genomics — Posted on 2019-12-23

535 Endocytic Clathrin Coats Develop Curvature at Early Stages of Their Formation

Willy, N.; Ferguson, J.; Silahli, S.; Cakez, C.; Hasan, F.; Chen, Y.; Wu, M.; Chang, H.; Travesset, A.; Li, S.; Zandi, R.; Li, D.; Betzig, E.; Cocucci, E.; Kural, C.

10.1101/715219 — biophysics — Posted on 2019-12-23

536 Transcriptome analysis of Tartary Buckwheat reveals the differential expression of salt pathway genes

Song, J.-N.; Liu, X.-H.; Wang, Y.-Q.; Yang, H.-B.

10.1101/869263 — genomics — Posted on 2019-12-23

537 Cross-scale dynamics and the evolutionary emergence of infectious diseases

Schreiber, S. J.; Ke, R.; Loverdo, C.; Park, M.; Ahsan, P.; Lloyd-Smith, J. O.

10.1101/066688 — epidemiology — Posted on 2019-12-23

538 Predicting changes in bee assemblages following state transitions at North American dryland ecotones

Kazenel, M. R.; Wright, K. W.; Bettinelli, J.; Griswold, T. L.; Whitney, K. D.; Rudgers, J. A.

10.1101/746990 — ecology — Posted on 2019-12-23

539 Biomimetic Aorta-Gonad-Mesonephros on-a-Chip to Study Human Developmental Hematopoiesis

Sugimura, R.; Ohta, R.; Mori, C.; Li, A.; Mano, T.; Sano, E.; Kosugi, K.; Nakahata, T.; Niwa, A.; Saito, M. K.; Torisawa, Y.-s.

10.1101/837856 — bioengineering — Posted on 2019-12-23

540 Migrant semipalmated sandpipers (Calidris pusilla) have over four decades steadily shifted towards safer stopover locations

Hope, D. D.; Lank, D. B.; Smith, P. A.; Paquet, J.; Ydenberg, R. C.

10.1101/741413 — animal behavior and cognition — Posted on 2019-12-23

541 Plasticity of Medicago truncatula seed dormancy relates to large-scale environment variation

Renzi, J. P.; Duchoslav, M.; Brus, J.; Hradilova, I.; Pechanec, V.; Vaclavek, T.; Machalov, J.; Hron, K.; Verdier, J.; Smykal, P.

10.1101/2019.12.22.886218 — plant biology — Posted on 2019-12-23

542 OBERON3 and SUPPRESSOR OF MAX2 1-LIKE proteins form a regulatory module specifying phloem identity

Wallner, E.-S.; Tonn, N.; Wanke, F.; Lopez-Salmeron, V.; Gebert, M.; Wenzl, C.; Lohmann, J. U.; Harter, K.; Greb, T.

10.1101/2019.12.21.885863 — plant biology — Posted on 2019-12-23

543 In vivo mRNA structure regulates miRNA cleavage in Arabidopsis

Yang, M.; Woolfenden, H. C.; Zhang, Y.; Fang, X.; Liu, Q.; Vigh, M. L.; Cheema, J.; Yang, X.; Norris, M.; Yu, S.; Carbonell, A.; Brodersen, P.; Wang, J.; Ding, Y.

10.1101/2019.12.21.885699 — molecular biology — Posted on 2019-12-23

544 TNF deficiency dysregulates inflammatory cytokine production leading to lung pathology and death during respiratory poxvirus infection

Tuazon Kels, M. J.; Zumaih, Z. A.; Ng, E.; Pandey, P.; Ruuls, S. R.; Korner, H.; Newsome, T. P.; Chaudhri, G.; Karupiah, G.

10.1101/2019.12.22.883728 — immunology — Posted on 2019-12-23

545 Prioritization of enhancer mutations by combining allele-specific chromatin accessibility with deep learning

Kalender Atak, Z.; Taskiran, I. I.; Flerin, C.; Mauduit, D.; Minnoye, L.; Hulsemans, G.; Christiaens, V.; Ghanem, G.-E.; Wouters, J.; Aerts, S.

10.1101/2019.12.21.885806 — genomics — Posted on 2019-12-23

546 Adenosine receptor and its downstream target mod(mdg4) modify the pathogenic effects of polyglutamine in a Drosophila model of Huntington's disease

Lin, Y.-H.; Ouns Maaroufi, H.; Kucerova, L.; Rouhova, L.; Filips, T.; Zurovec, M.

10.1101/2019.12.22.886143 — genetics — Posted on 2019-12-23

547 Degradation of key photosynthetic genes in the critically endangered semi-aquatic flowering plant Saniculiphyllum guangxiense (Saxifragaceae)

Folk, R. A.; Sewnath, N.; Xiang, C.; Sinn, B. T.; Guralnick, R. P.

10.1101/2019.12.22.886283 — evolutionary biology — Posted on 2019-12-23

548 Ecological and evolutionary drivers of hemoplasma infection and bacterial genotype sharing in a Neotropical bat community

Becker, D.; Speer, K.; Brown, A.; Fenton, M. B.; Washburne, A.; Altizer, S.; Streicker, D.; Plowright, R.; Chizhikov, V.; Simmons, N. B.; Volokhov, D.

10.1101/2019.12.21.885921 — ecology — Posted on 2019-12-23

549 Cryo-EM Structures and Regulation of Arabinofuranosyltransferase AftD from Mycobacteria

Tan, Y. Z.; Zhang, L.; Rodrigues, J.; Zheng, R. B.; Giacometti, S. I.; Rosario, A. L.; Kloss, B.; Dandey, V. P.; Wei, H.; Brunton, R.; Raczkowski, A. M.; Athayde, D.; Catalao, M. J.; Pimentel, M.; Clarke, O. B.; Lowary, T. L.; Archer, M.; Niederweis, M.; Potter, C. S.; Carragher, B.; Mancia, F.

10.1101/2019.12.22.885152 — biochemistry — Posted on 2019-12-23

550 Altitude-wise analysis of co-occurrence networks of mitochondrial genome in Asian population

Verma, R. K.; Giuliani, C.; Kalyakuina, A.; Kachhvah, A. D.; Ivanchenko, M.; Jalan, S.

10.1101/2019.12.21.885905 — systems biology — Posted on 2019-12-23

551 A Primer on Modeling and Measurement of Signaling Outcomes Affecting Decision Making in Cells: Methods for Determining Optimal and Incorrect Outcomes in Noisy Biochemical Dynamics

Ozen, M.; Lipniacki, T.; Levchenko, A.; Emamian, E. S.; Abdi, A.

10.1101/2019.12.21.885491 — systems biology — Posted on 2019-12-23

552 Seq2DFunc: 2-dimensional convolutional neural network on graph representation of synthetic sequences from massive-throughput assay

Guo, H.; Song, X.; Lindner, A. B.

10.1101/2019.12.22.886085 — synthetic biology — Posted on 2019-12-23

553 Spatial heterogeneity tunes the behavior of bacterial genetic circuits

Barajas, C.; Del Vecchio, D.

10.1101/2019.12.22.886473 — synthetic biology — Posted on 2019-12-23

554 Defense Biopriming and Antimicrobial Activity of Endophytic Bacteria and Associated Bacillus Species Contribute to Bacterial Crown Rot Tolerance in Papaya

Rivarez, M. P. S.; Parac, E. P.; Dimasingkil, S. F. M.; Magdalita, P. M.

10.1101/2019.12.22.886341 — plant biology — Posted on 2019-12-23

555 Parental effects via glyphosate-based herbicides in a bird model?

Ruuskanen, S.; Rainio, M.; Uusitalo, M.; Saikkonen, K.; Helander, M.

10.1101/2019.12.21.885855 — pharmacology and toxicology — Posted on 2019-12-23

556 Alteration of the premature tRNA landscape by gammaherpesvirus infection

Glaunsinger, B.; Tucker, J. M.; Schaller, A. M.; Willis, I. M.

10.1101/2019.12.22.886382 — molecular biology — Posted on 2019-12-23

557 Content of xylose, trehalose and L-citrulline in cucumber fermentations and utilization of such compounds by certain lactobacilli

Ucar, R. A.; Perez-Diaz, I. M.; Dean, L. L.

10.1101/2019.12.20.885608 — microbiology — Posted on 2019-12-23

558 Spatiotemporal analysis of host cell modification during herpes simplex virus 1 replication

Scherer, K. M.; Manton, J. D.; Soh, T. K.; Mascheroni, L.; Connor, V.; Crump, C. M.; Kaminski, C. F.

10.1101/2019.12.22.872002 — microbiology — Posted on 2019-12-23

559 Estimating allele-specific expression of SNVs from 10x Genomics Single-Cell RNA-Sequencing Data

NM, P.; Liu, H.; Bousounis, P.; Spurr, L.; Alomran, N.; Ibeawuchi, H.; Sein, J.; Reece-Stremtan, D.; Horvath, A.

10.1101/2019.12.22.886119 — genomics — Posted on 2019-12-23

560 Dissecting the regulatory activity and key sequence elements of loci with exceptional numbers of transcription factor associations

Ramaker, R. C.; Hardigan, A. A.; Goh, S.-T.; Partridge, E. C.; Wold, B.; Cooper, S. J.; Myers, R. M.

10.1101/2019.12.21.885830 — genomics — Posted on 2019-12-23

561 A genome-wide Approximate Bayesian Computation approach suggests only limited numbers of soft sweeps in humans over the last 100,000 years

Laval, G.; Patin, E.; Boutillier, P.; Quintana-Murci, L.

10.1101/2019.12.22.886234 — evolutionary biology — Posted on 2019-12-23

562 The Nucleome Data Bank: Web-based Resources to Simulate and Analyze the Three-Dimensional Genome

Contessoto, V. d. G.; Cheng, R. R.; Hajitaheri, A.; Dodero-Rojas, E.; Mello, M. F.; Aiden, E. L.; Wolynes, P. G.; Di Pierro, M.; Onuchic, J. N.

10.1101/2019.12.20.885145 — bioinformatics — Posted on 2019-12-23

563 Simplified geometric representations of protein structures identify complementary interaction interfaces

McCafferty, C. L.; Marcotte, E. M.; Taylor, D. W.

10.1101/2019.12.18.880575 — bioinformatics — Posted on 2019-12-23

564 A single-cell atlas of the human healthy airways

Deprez, M.; Zaragosi, L.-E.; Truchi, M.; Ruiz Garcia, S.; Arguel, M.-J.; Lebrigand, K.; Paquet, A.; Pee'r, D.; Marquette, C.-H.; Leroy, S.; BARBRY, P.

10.1101/2019.12.21.884759 — genomics — Posted on 2019-12-23

565 Optogenetic Stimulation of Pancreatic Function via Vagal Cholinergic Axons

Fontaine, A. K.; Ramirez, D. G.; Littich, S. F.; Piscopio, R.; Kravets, V.; Caldwell, J. H.; Weir, R. F.; Benninger, R. K.

10.1101/2019.12.21.885970 — bioengineering — Posted on 2019-12-23

566 XACT-seq comprehensively defines the promoter-position and promoter-sequence determinants for initial-transcription pausing

Winkelman, J. T.; Pukhrambam, C.; Vvedenskaya, I. O.; Zhang, Y.; Taylor, D. M.; Shah, P.; Ebright, R. H.; Nickels, B. E.

10.1101/2019.12.21.886044 — biochemistry — Posted on 2019-12-23

567 Towards a Digital Diatom: image processing and deep learning analysis of Bacillaria paradoxa dynamic morphology

Alicea, B. J.; Gordon, R.; Harbich, T.; Singh, U.; Singh, A.; Varma, V.

10.1101/2019.12.21.885897 — systems biology — Posted on 2019-12-23

568 GABA signalling in guard cells acts as a 'stress memory' to optimise plant water loss

Xu, B.; Long, Y.; Feng, X.; Zhu, X.; Sai, N.; Chirkova, L.; Herrmann, J.; Okamoto, M.; Hedrich, R.; Gilliham, M.

10.1101/2019.12.22.885160 — plant biology — Posted on 2019-12-23

569 Long reads from Nanopore sequencing as a tool for animal microbiome studies

Delgado, B.; Serrano, M.; Gonzalez, C.; Bach, A.; Gonzalez-Recio, O.

10.1101/2019.12.21.886028 — microbiology — Posted on 2019-12-23

570 Longitudinal linked read sequencing reveals ecological and evolutionary responses of a human gut microbiome during antibiotic treatment

Roodgar, M.; Good, B. H.; Garud, N. R.; Martis, S.; Avula, M.; Zhou, W.; Lancaster, S.; Lee, H.; Babveyh, A.; Nesamoney, S.; Pollard, K. S.; Snyder, M. P.

10.1101/2019.12.21.886093 — microbiology — Posted on 2019-12-23

571 Learning immune cell differentiation

Maslova, A.; Ramirez, R.; Ma, K.; Schmutz, H.; Wang, C.; Fox, C.; Ng, B.; Benoist, C.; Mostafavi, S.

10.1101/2019.12.21.885814 — genomics — Posted on 2019-12-23

572 Chromosome-level quality scaffolding of brown algal genomes using InstaGRAAL, a proximity ligation-based scaffolder

Baudry, L.; Marbouty, M.; Marie-Nelly, H.; Cormier, A.; Guiglielmoni, N.; Avia, K.; Loe Mie, Y.; Godfroy, O.; Sterck, L.; Cock, M.; Zimmer, C.; Coehlo, S. M.; Koszul, R.

10.1101/2019.12.22.882084 — genomics — Posted on 2019-12-23

573 Competition for access to mates predicts female-specific ornamentation and polyandry

Murray, R. L.; Herridge, E. J.; Ness, R. W.; Wiberg, R. A. W.; Bussiere, L. F.

10.1101/2019.12.21.885996 — evolutionary biology — Posted on 2019-12-23

574 Disentangling microbial associations from hidden environmental and technical factors via latent graphical models

Kurtz, Z. D.; Bonneau, R.; Müller, C. L.

10.1101/2019.12.21.885889 — bioinformatics — Posted on 2019-12-23

575 Dihydroartemisinin-loaded Magnetic Nanoparticles for Enhanced Chemodynamic Therapy

Guo, S.; Yao, X.; Jiang, Q.; Wang, K.; Zhang, Y.; Peng, H.; Tang, J.; Yang, W.

10.1101/2019.12.20.885400 — bioengineering — Posted on 2019-12-23

576 MRI tracking reveals selective accumulation of stem cell-derived magneto-extracellular vesicles in sites of injury

Han, Z.; Liu, S.; Pei, Y.; Ding, Z.; Li, Y.; Weiss, R. G.; van Zijl, P. C.; Bulte, J. W. M.; Cheng, L.; Liu, G.

10.1101/2019.12.22.885764 — bioengineering — Posted on 2019-12-23

577 A novel G protein-biased and subtype selective agonist for a G protein-coupled receptor discovered from screening herbal extracts

Zhang, B.; Zhao, S.; Yang, D.; Wu, Y.; Xin, Y.; Cao, H.; Huang, X.-P.; Cai, X.; Sun, W.; Ye, N.; Xu, Y.; Peng, Y.; Zhao, S.; Liu, Z.-J.; Zhong, G.; Wang, M.-W.; Shui, W.

10.1101/2019.12.22.883686 — biochemistry — Posted on 2019-12-23

578 Kinetic improvement of an algal diacylglycerol acyltransferase 1 via fusion with an acyl-CoA binding protein

Xu, Y.; Caldo, K. M. P.; Falarz, L.; Jayawardhane, K.; Chen, G. G.

10.1101/2019.12.21.885871 — plant biology — Posted on 2019-12-23

579 Successful field performance in dry-warm environments of soybean expressing the sunflower transcription factor HaHB4

Ribichich, K. F.; Chiozza, M.; Avalos-Britez, S.; Cabello, J. V.; Arce, A. L.; Watson, G.; Arias, C.; Portapila, M.; Trucco, F.; Otegui, M. E.; Chan, R. L.

10.1101/2019.12.21.885798 — plant biology — Posted on 2019-12-23

580 Transcriptomic responses to hypoxia in endometrial and decidual stromal cells

Rytkonen, K. T.; Saloniemi, T.; Mahmoudian, M.; Ma, X.; Perheentupa, A.; Elo, L. L.; Poutanen, M.; Wagner, G. P.

10.1101/2019.12.21.885657 — physiology — Posted on 2019-12-23

581 The Microbe Directory v2.0: An Expanded Database of Ecological and Phenotypical Features of Microbes.

Sierra, M. A.; Bhattacharya, C.; Ryon, K.; Meierovich, S.; Shaaban, H.; Westfall, D.; Mohammad, R.; Kuchin, K.; Afshinnekoo, E.; Danko, D. C.; Mason, C. E.

10.1101/2019.12.20.860569 — microbiology — Posted on 2019-12-23

582 Low basal expression and slow induction of IFITM3 puts immune cells at risk of influenza A infection

Wellington, D.; Yin, Z.; Zhang, L.; Forbester, J. L.; Kite, K.; Laurenson-Schafer, H.; Makvandi-Nejad, S.; Jin, B.; Bowes, E.; Manoharan, K.; Maldonado-Perez, D.; Verrill, C.; Humphreys, I.; Dong, T.

10.1101/2019.12.20.885590 — immunology — Posted on 2019-12-23

583 Neutrophil: Airway Epithelial Interactions Result in Increased Epithelial Damage and Viral Clearance during RSV Infection

Deng, Y.; Herbert, J.; Robinson, E.; Ren, L.; Smyth, R.; Smith, C. M.

10.1101/2019.12.20.885624 — immunology — Posted on 2019-12-23

584 Cell competition regulates the kinetics of thymopoiesis and thymus cellularity

Ramos, C. V.; Ballesteros-Arias, L.; Silva, J. G.; Nogueira, M.; Gjini, E.; Martins, V. C.

10.1101/2019.12.21.885673 — immunology — Posted on 2019-12-23

585 Advanced Whole Genome Sequencing Using a Complete PCR-free Massively Parallel Sequencing (MPS) Workflow

Xia, Z.; Jiang, Y.; Drmanac, R.; Shen, H.; Liu, P.; Li, Z.; Chen, F.; Jiang, H.; Shi, S.; Xi, Y.; Li, Q.; Wang, X.; Zhao, J.; Liang, X.; Xie, Y.; Wang, L.; Tian, W.; Berntsen, T.; Luo, Y.; Gong, M.; Li, J.; Xu, C.; Dai, S.; Mi, Z.; Ren, H.; Lin, Z.; Chen, A.; Zhang, W.; Mu, F.; Xu, X.

10.1101/2019.12.20.885517 — genomics — Posted on 2019-12-23

586 Cross-species analysis of melanoma enhancer logic using deep learning

Minnoye, L.; Taskiran, I. I.; Mauduit, D.; Fazio, M.; Van Aerschot, L.; Hulsemans, G.; Christiaens, V.; Makhzami, S.; Seltenhammer, M.; Karras, P.; Primot, A.; Cadieu, E.; van Rooijen, E.; Marine, J.-C.; Egidy Maskos, G.; Ghanem, G.-E.; Zon, L.; Wouters, J.; Aerts, S.

10.1101/2019.12.21.885715 — genomics — Posted on 2019-12-23

587 Characterization of the phototoxicity, chemigenetic profile, and mutational signatures of the chemotherapeutic CX-5461 in Caenorhabditis elegans

Ye, F. B.; Hamza, A.; Singh, T.; Flibotte, S.; Hieter, P.; O'Neil, N. J.

10.1101/2019.12.20.884981 — genetics — Posted on 2019-12-23

588 Genetic and morphological variation is associated with differences in cold-water tolerance and geographic expansion among invasive snails (Melanoides tuberculata) in central Texas

Harding, S. F.; Rodriguez, D.; Jackson, J.; Huffman, D.

10.1101/2019.12.20.884866 — zoology — Posted on 2019-12-23

589 Tracking self-citations in academic publishing

Kacem, A.; Flatt, J. W.; Mayr, P.

10.1101/2019.12.20.884031 — scientific communication and education — Posted on 2019-12-23

590 Big data from small tissues: extraction of high-quality RNA for different plant tissue types during oilseed Brassica spp. seed development for RNA-Sequencing

Siles, L.; Eastmond, P.; Kurup, S.

10.1101/2019.12.20.885012 — plant biology — Posted on 2019-12-23

591 Adaption of a Conventional ELISA to a 96-well ELISA-Array for Measuring the Antibody Responses to Influenza virus proteins, viruses and vaccines

Waltari, E.; Carabajal, E.; Sanyal, M.; Friedland, N.; McCutcheon, K. M.

10.1101/2019.12.20.885285 — immunology — Posted on 2019-12-23

592 New Tools for Genetically Targeting Myeloid Populations in the Central Nervous System

McKinsey, G. L.; Lizama, C. O.; Keown-Lang, A. E.; Niu, A.; Chee, E.; Santander, N.; Arnold, T. D.

10.1101/2019.12.20.885244 — immunology — Posted on 2019-12-23

593 EM-seq: Detection of DNA Methylation at Single Base Resolution from Picograms of DNA

Vaisvila, R.; Ponnaluri, V. K. C.; Sun, Z.; Langhorst, B. W.; Saleh, L.; Guan, S.; Dai, N.; Campbell, M. A.; Sexton, B. S.; Marks, K.; Samaranayake, M.; Samuelson, J. C.; Church, H. E.; Tamanaha, E.; Correa, I. R.; Pradhan, S.; Dimalanta, E. T.; Evans, T. C.; Williams, L.; Davis, T. B.

10.1101/2019.12.20.884692 — genomics — Posted on 2019-12-23

594 Cell type prioritization in single-cell data

Skinnider, M. A.; Squair, J. W.; Kathe, C.; Anderson, M. A.; Gautier, M.; Matson, K. J. E.; Milano, M.; Hutson, T. H.; Barraud, Q.; Phillips, A. A.; Foster, L. J.; La Manno, G.; Levine, A. J.; Courtine, G.

10.1101/2019.12.20.884916 — genomics — Posted on 2019-12-23

595 Genotyping and functional regression trees reveals environmental preferences of toxic cyanobacteria (Microcystis aeruginosa complex) along a wide spatial gradient

Martinez de la Escalera, G.; Segura, A. M.; Kruk, C.; Ghattas, B.; Piccini, C.

10.1101/2019.12.20.885111 — ecology — Posted on 2019-12-23

596 Metastasis-specific gene expression in autochthonous and allograft mouse mammary tumor models: stratificationand identification of targetable signatures

Ross, C.; Szczepanek, K.; Lee, M. P.; Yang, H. H.; Peer, C.; Kindrick, J.; Shankarappa, P.; Lin, Z.-W.; Sanford, J.; Figg, W.; Hunter, K.

10.1101/2019.12.20.885210 — cancer biology — Posted on 2019-12-23

597 HIV Care Prioritization using Phylogenetic Branch Length

Moshiri, N.; Smith, D. M.; Mirarab, S.

10.1101/2019.12.20.885202 — bioinformatics — Posted on 2019-12-23

598 Novel instrumented insole algorithm accurately approximates plantar flexor loading

Hullfish, T. J.; Baxter, J. R.

10.1101/2019.12.20.885228 — bioengineering — Posted on 2019-12-23

599 Real-time spectroscopic photoacoustic/ultrasound (PAUS) scanning with simultaneous fluence compensation and motion correction for quantitative molecular imaging

Jeng, G.-S.; Li, M.-L.; Kim, M.; Yoon, S. J.; Pitre, J. J.; Li, D. S.; Pelivanov, I.; O'Donnell, M.

10.1101/2019.12.20.885251 — bioengineering — Posted on 2019-12-23

600 Contrast-enhanced ultrasound with sub-micron sized contrast agents detects insulitis and beta-cell mass decline in mouse models of type 1 diabetes

Ramirez, D. G.; Abenojar, E.; Hernandez, C.; Papazian, L. A.; Passman, S.; Pham, V.; Exner, A. A.; Benninger, R. K. K.

10.1101/2019.12.20.885327 — bioengineering — Posted on 2019-12-23

601 The Kinase Chemogenomic Set (KCGS): An open science resource for kinase vulnerability identification

Wells, C. I.; Al-Ali, H.; Andrews, D. M.; Asquith, C. R. M.; Axtman, A. D.; Chung, M.; Dikic, I.; Ebner, D.; Elkins, J.; Ettmayer, P.; Fischer, C.; Frederiksen, M.; Gray, N. S.; Hatch, S. B.; Knapp, S.; Lee, S.; Lucking, U.; Michaelides, M.; Mills, C. E.; Muller, S.; Owen, D.; Picado, A.; Ramadan, K.; Saikatendu, K. S.; Schroder, M.; Stolz, A.; Tellechea, M.; Treiber, D. K.; Turunen, B. J.; Vilar, S.; Wang, J.; Zuercher, W.; Willson, T. M.; Drewry, D. H.

10.1101/2019.12.22.886523 — cell biology — Posted on 2019-12-23

602 Aerobic heterotrophy and RuBisCO-mediated CO2 metabolism in marine Thaumarchaeota

Reji, L.; Francis, C. A.

10.1101/2019.12.22.886556 — microbiology — Posted on 2019-12-23

603 Detection of genome-wide low-frequency mutations with Paired-End and Complementary Consensus Sequencing (PECC-Seq) revealed end-repair derived artifacts as residual errors

You, X.; Thiruppathi, S.; Liu, W.; Cao, Y.; Naito, M.; Furihata, C.; Honma, M.; Luan, Y.; Suzuki, T.

10.1101/2019.12.22.886440 — genomics — Posted on 2019-12-23

604 Mutualistic cross-feeding in microbial systems generates bistability via an Allee effect

Gonze, D.; Gelens, L.; Vet, S.

10.1101/2019.12.23.886622 — ecology — Posted on 2019-12-23

605 Pattern regulation in a regenerating jellyfish

Sinigaglia, C.; Peron, S.; Steger, J.; Houliston, E.; Leclere, L.

10.1101/2019.12.22.886200 — developmental biology — Posted on 2019-12-23

606 Skip segment Hirschsprung disease: modelling the trans-mesenteric origin of the enteric nervous system in the human colon

Newgreen, D. F.; Osborne, J. M.; Zhang, D.

10.1101/2019.12.22.886606 — developmental biology — Posted on 2019-12-23

607 Modeling acute kidney injury in kidney organoids with cisplatin

Digby, J. L. M.; Przepiorski, A.; Davidson, A. J.; Sander, V.

10.1101/2019.12.22.886572 — developmental biology — Posted on 2019-12-23

608 MOTS-c is an Exercise-Induced Mitochondrial-Encoded Regulator of Age-Dependent Physical Decline and Muscle Homeostasis

Reynolds, J. C.; Lai, R. W.; Woodhead, J. S. T.; Joly, J. H.; Mitchell, C. J.; Cameron-Smith, D.; Lu, R.; Cohen, P.; Graham, N. A.; Benayoun, B. A.; Merry, T. L.; Lee, C.

10.1101/2019.12.22.886432 — cell biology — Posted on 2019-12-23

609 SCSA: a cell type annotation tool for single-cell RNA-seq data

Cao, Y.; Wang, X.; Peng, G.

10.1101/2019.12.22.886481 — bioinformatics — Posted on 2019-12-23

610 Age and life expectancy clocks based on machine learning analysis of mouse frailty

Schultz, M. B.; Kane, A. E.; Mitchell, S. J.; MacArthur, M. R.; Warner, E.; Mitchell, J. R.; Howlett, S. E.; Bonkowski, M. S.; Sinclair, D. A.

10.1101/2019.12.20.884452 — physiology — Posted on 2019-12-23

611 A dichotomy in association of core transcription factors and gene regulation during the activated B-cell to plasmablast transition.

Cocco, M.; Care, M. A.; Al-Maskari, M.; Doody, G. M.; Tooze, R.

10.1101/2019.12.23.884007 — immunology — Posted on 2019-12-23

612 The DNA Methylation Landscape of Giant Viruses

Jeudy, S.; Rigou, S.; Alempic, J.-M.; Claverie, J.-M.; Abergel, C.; Legendre, M.

10.1101/2019.12.21.884833 — genomics — Posted on 2019-12-23

613 Sympatric ecological divergence with coevolution of niche preference

Payne, P.; Polechova, J.

10.1101/2019.12.20.884817 — evolutionary biology — Posted on 2019-12-23

614 Transfer Learning for Predicting Conversion from Mild Cognitive Impairment to Dementia of Alzheimer Type based on 3D-Convolutional Neural Network

Bae, J.; Stock, J.; Heywood, A.; Jung, Y.; Jenkins, L.; Katsaggelos, A.; Popuri, K.; Beg, F.; Wang, L.

10.1101/2019.12.20.884932 — bioinformatics — Posted on 2019-12-23

615 MGMM: an R package for fitting Gaussian Mixture Models on Incomplete Genomics Data

McCaw, Z. R.; Julienne, H.; Aschard, H.

10.1101/2019.12.20.884551 — bioinformatics — Posted on 2019-12-23

616 rMSIcleanup: An open-source tool for matrix-related peak annotation in mass spectrometry imaging and its application to silver-assisted laser desorption/ionization

Baquer, G.; Semente, L.; Garcia-Altares, M.; Lee, Y. J.; Chaurand, P.; Correig, X.; Rafols, P.

10.1101/2019.12.20.884957 — bioinformatics — Posted on 2019-12-23

617 Distance Indexing and Seed Clustering in Sequence Graphs

Chang, X.; Eizenga, J.; Novak, A. M.; Siren, J.; Paten, B.

10.1101/2019.12.20.884924 — bioinformatics — Posted on 2019-12-23

618 On-demand spatiotemporal programming of collective cell migration via bioelectric stimulation

Zajdel, T. J.; Shim, G.; Wang, L.; Rossello-Martinez, A.; Cohen, D. J.

10.1101/2019.12.20.884510 — bioengineering — Posted on 2019-12-23

619 A RIPOR2 in-frame deletion is a frequent and highly penetrant cause of adult-onset hearing loss

de Bruijn, S. E.; Smits, J. J.; Liu, C.; Lanting, C. P.; Beynon, A. J.; Blankevoort, j.; Oostrik, J.; Koole, W.; de Vrieze, E.; DOOFNL consortium, ; Cremers, C. W.; Cremers, F. P.; Roosing, S.; Yntema, H. G.; Kunst, H. P.; Zhao, B.; Pennings, R. J.; Kremer, H.

10.1101/2019.12.20.884726 — genetics — Posted on 2019-12-23

620 SSnet - Secondary Structure based End-to-End Learning model for Protein-Ligand Interaction Prediction

Verma, N.; Qu, X.; Trozzi, F.; Tao, Y.; Elsaied, M.; Larson, E.; Kraka, E.

10.1101/2019.12.20.884841 — bioinformatics — Posted on 2019-12-23

621 TIMP-3 facilitates binding of target metalloproteinases to the endocytic receptor LRP-1 and promotes scavenging of MMP-1

Carreca, A. P.; Pravata, V. M.; Murphy, G.; Nagase, H.; Troeberg, L.; Scilabra, S. D.

10.1101/2019.12.23.886762 — biochemistry — Posted on 2019-12-23

622 Exaptation of two ancient immune proteins into a new dimeric pore-forming toxin in snails

Giglio, M. L.; Ituarte, S.; Milesi, V.; Dreon, M. S.; Brola, T. R.; Caramelo, J. J.; Ip, J. C. H.; Mate, S.; Qiu, J.-W.; Otero, L. H.; Heras, H.

10.1101/2019.12.23.880021 — biochemistry — Posted on 2019-12-23

623 PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains Treg homeostasis

Danileviciute, E.; Zeng, N.; Capelle, C.; Paczia, N.; Gillespie, M. A.; Kurniawan, H.; Coowar, D.; Vogt-Weisenhorn, D.; Gomez-Giro, G.; Grusdat, M.; Baron, A.; Guerin, C.; Franchina, D. G.; Leonard, C.; Domingues, O.; Delhalle, S.; Wurst, W.; Schwamborn, J. C.; Krueger, R.; Ranish, J.; Brenner, D.; Linster, C. L.; Balling, R.; Ollert, M.; He, F. Q.

10.1101/2019.12.20.884809 — biochemistry — Posted on 2019-12-23

624 Fronto-temporal coupling dynamics during spontaneous activity and auditory processing

Garcia-Rosales, F.; Lopez-Jury, L.; Gonzalez-Palomares, E.; Cabral-Calerin, Y.; Hechavarria, J. C.

10.1101/2019.12.23.886770 — neuroscience — Posted on 2019-12-23

625 Sex differences in monetary reward and punishment processing are associated with fast dynamics of dopamine synthesis

Hahn, A.; Reed, M. B.; Pichler, V.; Michenthaler, P.; Rischka, L.; Godbersen, G. M.; Wadsak, W.; Hacker, M.; Lanzenberger, R.

10.1101/2019.12.23.886812 — neuroscience — Posted on 2019-12-23

626 Field evaluation of DNA amplification of human filarial and malaria parasites using mosquito excreta/feces

Minetti, C.; Pilotte, N.; Zulch, M.; Canelas, T.; Tettevi, E. J.; Veriegh, F. B.; Osei Atweneboana, M.; Reimer, L. J.

10.1101/2019.12.23.880740 — microbiology — Posted on 2019-12-23

627 Insights into the involvement of spliceosomal mutations in myelodysplastic disorders from an analysis of SACY-1/DDX41 in Caenorhabditis elegans

Greenstein, D.; Tsukamoto, T.; Gearhart, M. D.; Kim, S.; Mekonnen, G.; Spike, C. A.

10.1101/2019.12.23.886804 — genetics — Posted on 2019-12-23

628 Unraveling nanotopography of cell surface receptors

Franke, C.; Chum, T.; Kvicalova, Z.; Glatzova, D.; Rodriguez, A.; Helmerich, D.; Frank, O.; Brdicka, T.; van de Linde, S.; Cebecauer, M.

10.1101/2019.12.23.884460 — cell biology — Posted on 2019-12-23

629 Discovery of dual inhibitors of KPC-3 and KPC-15 of Klebsiella pneumoniae - a ligand and structure based virtual screening study

Sharma, S.; Kumar-M, P.; Yadav, R.; Gupta, N.

10.1101/2019.12.23.886671 — bioinformatics — Posted on 2019-12-23

630 Multi-corneal barriers-on-a-chip to recapitulate eye blinking shear stress forces

Abdalkader, R.; Kamei, K.-i.

10.1101/2019.12.23.886242 — bioengineering — Posted on 2019-12-23

631 Emergence of neural dynamics within a co-ordinate space of large-scale neural hierarchies

Karapanagiotidis, T.; Vidaurre, D.; Quinn, A. J.; Vatansever, D.; Poerio, G. L.; Turnbull, A.; Leech, R.; Bernhardt, B.; Jefferies, E.; Margulies, D. S.; Nichols, T.; Woolrich, M. W.; Smallwood, J.

10.1101/2019.12.21.885772 — neuroscience — Posted on 2019-12-23

632 NADPH diaphorase neuronal dystrophy in gracile nucleus, cuneatus nucleus and spinal trigeminal nucleus in aged rat

Hou, W.; Jia, Y.; Li, Y.; Wei, Z.; Wen, X.; Rao, C.; Xu, X.; Li, F.; Wu, X.; Sun, H.; Li, H.; Huang, Y.; Sun, J.; Shu, G.; Wang, X.; Zhang, T.; Shi, G.; Guo, A.; Xu, S.; Du, G.; Tan, H.

10.1101/2019.12.21.885988 — neuroscience — Posted on 2019-12-23

633 Visual self-motion cues are impaired in Parkinson's disease yet over-weighted during visual-vestibular integration

Yakubovich, S.; Israeli-Korn, S.; Halperin, O.; Yahalom, G.; Hassin-Baer, S.; Zaidel, A.

10.1101/2019.12.22.884940 — neuroscience — Posted on 2019-12-23

634 The functional organization of high-level visual cortex determines the representation of complex visual stimuli

Kliger, L.; Yovel, G.

10.1101/2019.12.22.852293 — neuroscience — Posted on 2019-12-23

635 Quantifiable In Vivo Imaging Biomarkers of Retinal Regeneration by Photoreceptor Cell Transplantation

Liu, Y. V.; Sodhi, S.; Xue, G.; Teng, D.; Agakishiev, D.; McNally, M. M.; Harris-Bookman, S.; McBride, C.; Konar, G.; Singh, M.

10.1101/2019.12.21.884973 — neuroscience — Posted on 2019-12-23

636 An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of a-synuclein

Kara, E.; Crimi, A.; Wiedmer, A.; Emmenegger, M.; Manzoni, C.; Bandres-Ciga, S.; D Sa, K.; Reynolds, R. H.; Botia, J. A.; Losa, M.; Lysenko, V.; Carta, M.; Heinzer, D.; Avar, M.; Chincisan, A.; Blauwendraat, C.; Garcia Ruiz, S.; Pease, D.; Mottier, L.; Carrella, A.; Schneider, D.; Magalhaes, A.; Aemisegger, C.; Theocharides, A. P. A.; Fan, Z.; Marks, J. D.; Hopp, S. C.; Lewis, P. A.; Ryten, M.; Hardy, J.; Hyman, B. T.; Aguzzi, A.

10.1101/2019.12.23.886838 — neuroscience — Posted on 2019-12-23

637 Innovation in solitary bees is driven by exploration, shyness and activity levels

Collado, M. A.; Menzel, R.; Sol, D.; Bartomeus, I.

10.1101/2019.12.23.884619 — animal behavior and cognition — Posted on 2019-12-23

638 Sex Differences in Behavioral Responses during a Conditioned Flight Paradigm

Borkar, C. D.; Dorofeikova, M.; Le, Q.-S. E.; Vutukuri, R.; Vo, C.; Hereford, D.; Resendez, A.; Basavanhalli, S.; Sifnugel, N.; Fadok, J. P.

10.1101/2019.12.20.885038 — animal behavior and cognition — Posted on 2019-12-23

639 Natural Zeitgebers cannot compensate for the loss of a functional circadian clock in timing of a vital behaviour in Drosophila

Ruf, F.; Mitesser, O.; Mungwa, S. T.; Horn, M.; Rieger, D.; Hovestadt, T.; Wegener, C.

10.1101/2019.12.22.886309 — animal behavior and cognition — Posted on 2019-12-23

640 DeepLabStream: Closing the loop using deep learning-based markerless, real-time posture detec-tion

Schweihoff, J. F.; Loshakov, M.; Pavlova, I.; Kück, L.; Ewell, L. A.; Schwarz, M. K.

10.1101/2019.12.20.884478 — animal behavior and cognition — Posted on 2019-12-23

641 Population Responses Represent Vocalization Identity, Intensity, and Signal-to-Noise Ratio in Primary Auditory Cortex

Ni, R.; Bender, D. A.; Barbour, D. L.

10.1101/2019.12.21.886101 — neuroscience — Posted on 2019-12-23

642 Multimodal Learning of Pheromone Locations

Pardasani, M.; Marathe, S. D.; Dalvi, U.; Abraham, N. M.

10.1101/2019.12.22.886564 — neuroscience — Posted on 2019-12-23

643 A dynamic normalization model of temporal attention

Denison, R. N.; Carrasco, M.; Heeger, D. J.

10.1101/2019.12.21.886051 — neuroscience — Posted on 2019-12-23

644 Diverse demographic histories in a guild of hymenopteran parasitoids

Walton, W.; Stone, G. N.; Lohse, K.

10.1101/2019.12.20.884403 — evolutionary biology — Posted on 2019-12-22

645 Loss of prdm1a accelerates melanoma onset and progression

Iwanaga, R.; Truong, B.; Lambert, K.; Vyas, R.; Orlicky, D.; Shellman, Y.; Tan, A.-C.; Ceol, C.; Artinger, K.

10.1101/2019.12.20.884767 — cancer biology — Posted on 2019-12-22

646 Concerted cutting by Spo11 illuminates DNA break mechanisms and initiates gap repair during meiosis

Johnson, D.; Crawford, M.; Cooper, T.; Claeys Bouuaert, C.; Keeney, S.; llorente, B.; Neale, M. J.; Garcia, V.

10.1101/2019.12.18.881268 — molecular biology — Posted on 2019-12-22

647 Conformational state switching and pathways of chromosome dynamics in cell cycle

Chu, X.; Wang, J.

10.1101/2019.12.20.885335 — biophysics — Posted on 2019-12-22

648 Distinct roles of microtubules and actin filaments in defining dendritic architecture

Nanda, S.; Bhattacharjee, S.; Cox, D. N.; Ascoli, G. A.

10.1101/2019.12.22.885004 — neuroscience — Posted on 2019-12-22

649 broad controls leg imaginal disc morphogenesis in Drosophila via regulation of cell shape changes and remodeling of extracellular matrix

Rice, C.; Wang, X.; Macdonald, S.; Ward, R.

10.1101/2019.12.21.885848 — developmental biology — Posted on 2019-12-22

650 Niacin Stimulates Mammary Gland Development in Pubertal Mice through Activation of the AKT/mTOR and ERK1/2 Signaling Pathways

Cao, Y.; Liu, J.; Ma, L.; Zhang, Q.; Wang, J.; Guo, W.; Kan, X.; Li, Y.; Cheng, J.; Fu, S.

10.1101/2019.12.21.885756 — developmental biology — Posted on 2019-12-22

651 A switch in cilia-mediated Hedgehog signaling controls muscle stem cell quiescence and cell cycle progression

Cruz-Migoni, S. B.; Mohd Imran, K.; Wahid, A.; Rahman, O.; Briscoe, J.; Borycki, A.-G.

10.1101/2019.12.21.884601 — developmental biology — Posted on 2019-12-22

652 Retrograde transport of mannose-6-phosphate receptor depends on several sorting machineries as analyzed by sulfatable nanobodies

Buser, D. P.; Spiess, M.

10.1101/2019.12.21.885939 — cell biology — Posted on 2019-12-22

653 Multiplexed imaging of nucleome architectures in single cells of mammalian tissue

Liu, M.; Lu, Y.; Yang, B.; Chen, Y.; Radda, J. S. D.; Hu, M.; Katz, S. G.; Wang, S.

10.1101/2019.12.20.885277 — cell biology — Posted on 2019-12-22

654 Role of HP1β during spermatogenesis and DNA replication

Charakha, V.; Tiwari, A.; Pandita, R. K.; Hunt, C. K.; Pandita, T. K.

10.1101/2019.12.22.886424 — cell biology — Posted on 2019-12-22

655 PSF broadening due to fluorescence emission

Becker, J.; Heintzmann, R.

10.1101/2019.12.21.885707 — biophysics — Posted on 2019-12-22

656 Real-time monitoring of cotranscriptional riboswitch folding and switching

Hua, B.; Jones, C. P.; Mitra, J.; Murray, P. J.; Rosenthal, R.; FerreDAmare, A. R.; Ha, T.

10.1101/2019.12.20.885053 — biophysics — Posted on 2019-12-22

657 The use of 'artificial saliva' as a neutral control condition in gustatory research

Hensels, I. S.; Talmi, D.; Baines, S.

10.1101/2019.12.18.880880 — neuroscience — Posted on 2019-12-22

658 Is the rat prefrontal cortex crucial for cognitive control during spatial cognition?

Park, E. H.; O'Reilly, K.; Taborga, D.; Nicholas, K.; Ahmed, A.; Ruiz, N.; Fenton, A.

10.1101/2019.12.20.884262 — neuroscience — Posted on 2019-12-22

659 A toolbox for automated video analysis of rodents engaged in string-pulling: Phenotyping motor behavior of mice for sensory, whole-body and bimanual skilled hand function

Inayat, S.; Singh, S.; Ghasroddashti, A.; Qandeel, ; Egodage, P.; Whishaw, I. Q.; Mohajerani, M.

10.1101/2019.12.18.881342 — neuroscience — Posted on 2019-12-22

660 Human tauopathies are not associated with an activated unfolded protein response

Pitera, A.; Hartnell, I. J.; Boche, D.; O'Connor, V.; Deinhardt, K.

10.1101/2019.12.20.884437 — neuroscience — Posted on 2019-12-22

661 Multiplexed single-cell transcriptomic analysis of normal and impaired lung development in the mouse

Hurskainen, M. K.; Mizikova, I.; Cook, D. P.; Cyr-Depauw, C.; Lesage, F.; Andersson, N.; Helle, E.; Renesme, L.; Jankov, R. P.; Heikinheimo, M.; Vanderhyden, B.; Thebaud, B.

10.1101/868802 — cell biology — Posted on 2019-12-22

662 Monosynaptic tracing success depends critically on helper virus concentrations

Lavin, T. K.; Jin, L.; Lea, N. E.; Wickersham, I.

10.1101/736017 — neuroscience — Posted on 2019-12-22

663 Classical and controlled auditory mismatch responses to multiple physical deviances in anaesthetised and conscious mice

O'Reilly, J. A.; Conway, B. A.

10.1101/831016 — neuroscience — Posted on 2019-12-22

664 Combining case-control status and family history of disease increases association power

Hujoel, M. L. A.; Gazal, S.; Loh, P.-R.; Patterson, N.; Price, A. L.

10.1101/722645 — genetics — Posted on 2019-12-22

665 Non-Homology-Based Prediction of Gene Functions

Dai, X.; Xu, Z.; Liang, Z.; Tu, X.; Zhong, S.; Schnable, J. C.; Li, P.

10.1101/730473 — bioinformatics — Posted on 2019-12-22

666 species2vec: A novel method for species representation

Angelov, B.

10.1101/461996 — ecology — Posted on 2019-12-22

667 Improving the interpretability of species distribution models by using local approximations

Angelov, B.

10.1101/454991 — ecology — Posted on 2019-12-22

668 Elucidating the Influence of Linker Histone Variants on Chromatosome Dynamics and Energetics

Woods, D. C.; Weresczczynski, J.

10.1101/660076 — biophysics — Posted on 2019-12-22

669 Transient intracellular acidification regulates the core transcriptional heat shock response

Triandafillou, C. G.; Katanski, C. D.; Dinner, A. R.; Drummond, D. A.

10.1101/414706 — cell biology — Posted on 2019-12-22

670 Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage-clamp experiments

Lei, C. L.; Clerx, M.; Whittaker, D. G.; Gavaghan, D. J.; de Boer, T. P.; Mirams, G. R.

10.1101/2019.12.20.884353 — biophysics — Posted on 2019-12-22

671 RNA-seq transcriptome analysis reveals LTR-retrotransposons modulation in Human Peripheral Blood Mononuclear Cells (PBMCs) after in vivo Lipopolysaccharides (LPS) injection

Pisano, M. P.; Tabone, O.; Bodinier, M.; Grandi, N.; Textoris, J.; Mallet, F.; Tramontano, E.

10.1101/2019.12.20.884494 — microbiology — Posted on 2019-12-22

672 Optimized breeding strategies to harness Genetic Resources with different performance levels

Allier, A.; Teyssedre, S.; Lehermeier, C.; Moreau, L.; Charcosset, A.

10.1101/2019.12.20.885087 — genetics — Posted on 2019-12-22

673 Phasic and tonic serotonin modulate alarm reactions and post-exposure behavior in zebrafish

Lima-Maximino, M.; Pyterson, M. P.; do Carmo Silva, R. X.; Gomes, G. C. V.; Rocha, S. P.; Herculano, A. M.; Rosemberg, D. B.; Maximino, C.

10.1101/827824 — neuroscience — Posted on 2019-12-22

674 Structural features recapitulate collective dynamics of inhibitory networks

Garg, S.; Singh, D.

10.1101/2019.12.17.879726 — neuroscience — Posted on 2019-12-22

675 Two separate roles for the transcription coactivator SAGA and a set of genes redundantly regulated by TFIID and SAGA

Donczew, R.; Warfield, L.; Pacheco, D.; Erijman, A.; Hahn, S.

10.1101/745059 — molecular biology — Posted on 2019-12-22

676 Close relationships between coral-associated Chromera strains despite differences within the Symbiodiniaceae

Mohamed, A. R.; Chan, C. X.; Ragan, M. A.; Zhang, J.; Cooke, I.; Ball, E.; Miller, D. J.

10.1101/825992 — genomics — Posted on 2019-12-22

677 SHAMAN: a user-friendly website for metataxonomic analysis from raw reads to statistical analysis

Volant, S.; Lechat, P.; Woringer, P.; Motreff, L.; Malabat, C.; Kennedy, S.; Ghozlane, A.

10.1101/2019.12.18.880773 — bioinformatics — Posted on 2019-12-22

678 Extensive Mammalian Germline Genome Engineering

Yue, Y.; Kan, Y.; Xu, W.; Zhao, H.-Y.; Zhou, Y.; Song, X.; Wu, J.; Xiong, J.; Goswami, D.; Yang, M.; Lamriben, L.; Xu, M.; Zhang, Q.; Yu, L.; Guo, J.; Mao, S.; Jiao, D.; Nguyen, T. D.; Li, Z.; Layer, J. V.; Li, M.; Paragas, V.; Youd, M. E.; Sun, Z.; Ding, Y.; Wang, W.; Dou, H.; Song, L.; Wang, X.; Le, L.; Fang, X.; George, H.; Anand, R.; Wang, S. Y.; Westlin, W. F.; Guell, M.; Markmann, J.; Qin, W.; Gao, Y.; Wei, H.-J.; Church, G. M.; Yang, L.

10.1101/2019.12.17.876862 — synthetic biology — Posted on 2019-12-22

679 Elimination of galanin synthesis in noradrenergic neurons reduces galanin in select brain areas and promotes active coping behaviors

Tillage, R. P.; Sciolino, N. R.; Plummer, N. W.; Lustberg, D.; Liles, L. C.; Hsiang, M.; Powell, J. M.; Smith, K. G.; Jensen, P.; Weinshenker, D.

10.1101/651943 — neuroscience — Posted on 2019-12-22

680 Example Based Hebbian Learning may be sufficient to support Human Intelligence

Wong, E. C.

10.1101/758375 — neuroscience — Posted on 2019-12-22

681 Staphylococcus aureus staphyloxanthin expression is not controlled by Hfq

Liu, W.; Boudry, P.; Bohn, C.; Bouloc, P.

10.1101/2019.12.17.876839 — microbiology — Posted on 2019-12-22

682 Transcriptome analysis of Tartary Buckwheat reveals the differential expression of salt pathway genes

Song, J.-N.; Liu, X.-H.; Wang, Y.-Q.; Yang, H.-B.

10.1101/869263 — genomics — Posted on 2019-12-22

683 Uniparental mitochondrial inheritance in Cryptococcus is controlled by the pheromone and pheromone receptor mating-type locus

Sun, S.; Fu, C.; Ianiri, G.; Heitman, J.

10.1101/813998 — genetics — Posted on 2019-12-22

684 Assembly of a young vertebrate Y chromosome reveals convergent signatures of sex chromosome evolution

Peichel, C. L.; McCann, S. R.; Ross, J. A.; Naftaly, A. F. S.; Urton, J. R.; Cech, J. N.; Grimwood, J.; Schmutz, J.; Myers, R. M.; Kingsley, D. M.; White, M. A.

10.1101/2019.12.12.874701 — evolutionary biology — Posted on 2019-12-22

685 Finding a suitable library size to call variants in RNA-seq

Quaglieri, A.; Flensburg, C.; Speed, T. P.; Majewski, I. J.

10.1101/2019.12.18.881870 — bioinformatics — Posted on 2019-12-22

686 Geometry of Ranked Nearest Neighbour Interchange Space of Phylogenetic Trees

Collienne, L.; Elmes, K.; Fischer, M.; Bryant, D. J.; Gavryushkin, A.

10.1101/2019.12.19.883603 — bioinformatics — Posted on 2019-12-22

687 One-Pot E. coli Cell-Free Extract for in vitro Expression of Disulfide Bonded Proteins

Dopp, J. L.; Reuel, N. F.

10.1101/2019.12.19.883413 — bioengineering — Posted on 2019-12-22

688 Irrelevant auditory and tactile signals, but not visual signals, interact with the target onset and modulate saccade latencies

Vidal, M.; Desantis, A.; Madelain, L.

10.1101/723510 — neuroscience — Posted on 2019-12-22

689 Suppression of homeostatic gene expression and increased expression of metabolism-related genes are early features of glaucoma in optic nerve head microglia

Tribble, J. R.; Harder, J. M.; Williams, P. A.; John, S. W.

10.1101/856427 — neuroscience — Posted on 2019-12-22

690 The interaction of aging and oxidative stress contributes to pathogenesis in mouse and human Huntington disease neurons

Machiela, E.; Jeloka, R.; Caron, N. S.; Mehta, S.; Schmidt, M. E.; Tom, C. M.; Potluri, N.; Xie, Y.; Mattis, V. B.; Hayden, M. R.; Southwell, A. L.

10.1101/800268 — neuroscience — Posted on 2019-12-22

691 A sulfoglycolytic Entner-Doudoroff pathway in Rhizobium leguminosarum bv. trifolii SRDI565

Li, J.; Epa, R.; Lingford, J. P.; Scott, N.; Skoneczny, D.; Sharma, M.; Snow, A. J.; Goddard-Borger, E. D.; Davies, G. J.; McConville, M. J.; Williams, S. J.

10.1101/2019.12.17.868638 — microbiology — Posted on 2019-12-22

692 Reduced transfer coefficient of carbon monoxide in pulmonary arterial hypertension implicates rare protein-truncating variants in KDR

Swietlik, E. M.; Greene, D.; Zhu, N.; Megy, K.; Cogliano, M.; Rajaram, S.; Pandya, D.; Tilly, T.; Lutz, K. A.; Welch, C. C. L.; Pauciulo, M. W.; Southgate, L.; Martin, J. M.; Treacy, C. M.; UK National Cohort Study of Idiopathic and Heritable PAH, ; NIHR Bioresource for Translational Research - Rare Diseases, ; US PAH Biobank Enrolling Centers' Investigators, ; Lawrie, A.; Wilkins, M. R.; Trembath, R. C.; Shen, Y.; Wendy, C. K.; Swift, A. J.; Nichols, W. C.; Morrell, N. W.; Gräf, S.

10.1101/2019.12.11.871210 — genetics — Posted on 2019-12-22

693 Plasmodium condensin core subunits (SMC2/SMC4) mediate atypical mitosis and are essential for parasite proliferation and transmission

Pandey, R.; Abel, S.; Boucher, M.; Wall, R. J.; Zeeshan, M.; Rea, E.; Freville, A.; Lu, X. M.; Brady, D.; Daniel, E.; Stanway, R. R.; Wheatley, S.; Batugedara, G.; Hollin, T.; Bottrill, A. R.; Gupta, D.; Holder, A. A.; Le Roch, K. G.; Tewari, R.

10.1101/674028 — cell biology — Posted on 2019-12-22

694 The accidental ally: Nucleosomal barriers can accelerate cohesin mediated loop formation in chromatin

Maji, A.; Padinhateeri, R.; Mitra, M. K.

10.1101/861161 — biophysics — Posted on 2019-12-22

695 Mechanical model of muscle contraction. 1. Force-velocity relationship

Louvet, S.

10.1101/2019.12.16.878793 — biophysics — Posted on 2019-12-22

696 A hierarchical framework for segmenting movement paths

Getz, W. M.

10.1101/819763 — ecology — Posted on 2019-12-22

697 eIF3 associates with 80S ribosomes to promote translation elongation, mitochondrial homeostasis, and muscle health

Lin, Y.; Li, F.; Huang, L.; Duan, H.; Fang, J.; Sun, L.; Xing, X.; Tian, G.; Cheng, Y.; Yang, X.; Wolf, D. A.

10.1101/651240 — cell biology — Posted on 2019-12-22

698 STAT3 localizes in mitochondria-associated ER membranes instead of in mitochondria

Su, Y.; Huang, X.; Huang, Z.; Huang, T.; Xu, Y.; Yi, C.

10.1101/2019.12.18.880567 — cell biology — Posted on 2019-12-22

699 Alzheimers disease-related dysregulation of protein synthesis causes key pathological features with ageing

Ghosh, A.; Mizuno, K.; Tiwari, S. S.; Proitsi, P.; Gomez Perez-Nievas, B.; Glennon, E.; Martinez-Nunez, R. T.; Giese, K. P.

10.1101/2019.12.20.884783 — neuroscience — Posted on 2019-12-21

700 Human follicular helper T cell promoter connectomes reveal novel genes and regulatory elements at SLE GWAS loci

Su, C.; Johnson, M. E.; Torres, A.; Thomas, R. M.; Manduchi, E.; Sharma, P.; Le Coz, C.; Leonard, M. E.; Lu, S.; Hodge, K. M.; Chesi, A.; Pippin, J.; Romberg, N.; Grant, S. F.; WELLS, A. D.

10.1101/2019.12.20.885426 — genomics — Posted on 2019-12-21

701 A community-maintained standard library of population genetic models

Adrion, J. R.; Cole, C. B.; Dukler, N.; Galloway, J. G.; Gladstein, A. L.; Gower, G.; Kyriazis, C. C.; Ragsdale, A. P.; Tsambos, G.; Baumdicker, F.; Carlson, J.; Cartwright, R. A.; Durvasula, A.; Kim, B. Y.; McKenzie, P.; Messer, P. W.; Noskova, E.; Ortega-Del Vecchyo, D.; Struck, T. J.; Gravel, S.; Gutenkunst, R. N.; Ralph, P. L.; Schrider, D. R.; Siepel, A.; Kelleher, J.; Kern, A. D.

10.1101/2019.12.20.885129 — evolutionary biology — Posted on 2019-12-21

702 The open bar is closed: restructuration of a native parasitoid community following successful control of an invasive pest.

Muru, D.; Borowiec, N.; Thaon, M.; Ris, N.; Vercken, E.

10.1101/2019.12.20.884908 — ecology — Posted on 2019-12-21

703 Measuring the spatial heterogeneity on the reduction of vaginal fistula burden in Ethiopia between 2005 and 2016

Deribe, K.; Fronterre, C.; Dejene, T.; Biadgilign, S.; Deribew, A.; Abdullah, M.; Cano, J.

10.1101/2019.12.21.885632 — bioinformatics — Posted on 2019-12-21

704 Loss of genetic diversity in wild fish populations reduces biomass stability over time.

Prunier, J. G.; Chevalier, M.; Raffard, A.; Loot, G.; Poulet, N.; Blanchet, S.

10.1101/2019.12.20.884734 — ecology — Posted on 2019-12-21

705 High-throughput cryo-EM enabled by user-free preprocessing routines

Li, Y.; Cash, J. N.; Tesmer, J. J. G.; Cianfrocco, M. A.

10.1101/2019.12.20.885541 — biophysics — Posted on 2019-12-21

706 Single cell transcriptomic analysis identifies Langerhans cells immunocompetency is critical for IDO1- dependent ability to induce tolerogenic T cells.

Davies, J.; Sirvent, S.; Vallejo, A. F.; Clayton, K.; Porter, G.; Stumpf, P.; West, J.; Ardern-Jones, M.; Singh, H.; MacArthur, B.; Polak, M. E.

10.1101/2019.12.20.884130 — systems biology — Posted on 2019-12-21

707 Endosperm and seed transcriptomes reveal possible roles for small RNA pathways in wild tomato hybrid seed failure

Florez-Rueda, A. M.; Roth, M.; Fiscalini, F.; Grossniklaus, U.; Staedler, T.

10.1101/2019.12.20.884387 — plant biology — Posted on 2019-12-21

708 Micrografting device for testing environmental conditions for grafting and systemic signaling in Arabidopsis

Tsutsui, H.; Yanagisawa, N.; Kawakatsu, Y.; Ikematsu, S.; Sawai, Y.; Tabata, R.; Arata, H.; Higashiyama, T.; Notaguchi, M.

10.1101/2019.12.20.885525 — plant biology — Posted on 2019-12-21

709 Elongation of stigmatic papillae induced by heat stress is associated with disturbance of pollen attachment in Arabidopsis thaliana

Katano, K.; Oi, T.; Suzuki, N.

10.1101/2019.12.21.885640 — plant biology — Posted on 2019-12-21

710 Cerebellar dopamine D2 receptors regulate preference for social novelty

Cutando, L.; Puighermanal, E.; Castell, L.; Tarot, P.; Belle, M.; Bertaso, F.; Arango-Lievano, M.; Ango, F.; Rubinstein, M.; Chetodal, A.; Mameli, M.; Valjent, E.

10.1101/2019.12.20.884288 — neuroscience — Posted on 2019-12-21

711 Pyk2 Overexpression in Postsynaptic Neurons Blocks Aβ1-42-induced Synaptotoxicity in a Microfluidic Co-Culture Model

Kilinc, D.; Vreulx, A.-C.; Mendes, T.; Flaig, A.; Verschoore, M.; Demiautte, F.; Amouyel, P.; Eysert, F.; Dourlen, P.; Chapuis, J.; Malmanche, N.; Checler, F.; Lambert, J.-C.

10.1101/2019.12.20.884205 — neuroscience — Posted on 2019-12-21

712 PiVR: an affordable and versatile closed-loop platform to study unrestrained sensorimotor behavior

Tadres, D.; Louis, M.

10.1101/2019.12.20.885442 — neuroscience — Posted on 2019-12-21

713 Dynamics of T cell activation mediated by eIF3 interactions with T cell receptor mRNAs

De Silva, D.; Ferguson, L.; Smith, B. E.; Chin, G. H.; Apathy, R. A.; Roth, T. L.; Kudla, M.; Marson, A.; Ingolia, N. T.; Cate, J. H. D.

10.1101/2019.12.20.885558 — molecular biology — Posted on 2019-12-21

714 tRNA-derived fragments and microRNAs in the maternal-fetal interface of a mouse maternal-immune-activation autism model

Su, Z.; Frost, E. L.; Lammert, C. R.; Przanowska, R. K.; Lukens, J. R.; Dutta, A.

10.1101/2019.12.20.884650 — molecular biology — Posted on 2019-12-21

715 Applying Nanopore sequencing to a One-Health scenario for colistin resistance transmission among pigs, cows and the farmer

Vines, J.; Cusco, A.; Napp, S.; Gonzalez, J.; Perez de Rozas, A.; Francino, O.; Migura-Garcia, L.

10.1101/2019.12.20.884395 — microbiology — Posted on 2019-12-21

716 Homologues of key circadian clock genes present in Verticillium dahliae do not direct circadian programs of development or mRNA abundance.

Cascant-Lopez, E.; Crosthwaite, S. K.; Johnson, L. J.; Harrison, R. J.

10.1101/2019.12.20.883116 — microbiology — Posted on 2019-12-21

717 Optimal maturation of the SIV-specific CD8+ T-cell response after primary infection is associated with natural control of SIV. ANRS SIC study

Passaes, C.; Millet, A.; Madelain, V.; Monceaux, V.; David, A.; Versmisse, P.; Sylla, N.; Gostick, E.; Price, D. A.; Blancher, A.; Bosquet, N.; Pancino, G.; Le Grand, R.; Lambotte, O.; Muller-Trutwin, M.; Rouzioux, C.; Guedj, J.; Avettand-Fenoel, V.; Vaslin, B.; Saez-Cirion, A.

10.1101/2019.12.20.885459 — immunology — Posted on 2019-12-21

718 A single-cell survey of Drosophila blood

Tattikota, S. G.; Hu, Y.; Liu, Y.; Cho, B.; Barrera, V.; Steinbaugh, M.; Yoon, S.-H.; Comjean, A.; Li, F.; Dervis, F.; Hung, R.-J.; Nam, J.-W.; Ho Sui, S.; Shim, J.; Perrimon, N.

10.1101/2019.12.20.884999 — immunology — Posted on 2019-12-21

719 A new method for long-read sequencing of animal mitochondrial genomes: application to the identification of equine mitochondrial DNA variants

Dhorne-Pollet, S.; Barrey, E.; Pollet, N.

10.1101/2019.12.20.884486 — genomics — Posted on 2019-12-21

720 Chlorotoxin Conjugated with Saporin Reduces Viability of ML-1 Thyroid Cancer Cells In Vitro

Thomas, J.; Rizvanovic, H.; Pinheiro, A. D.; Kim, K.

10.1101/2019.12.20.885483 — cancer biology — Posted on 2019-12-21

721 Coarse-Grained Modeling of DNA Plectoneme Formation in the Presence of Base-Pair Mismatches

Desai, P. R.; Brahmachari, S.; Marko, J. F.; Das, S.; Neuman, K. C.

10.1101/2019.12.20.885533 — biophysics — Posted on 2019-12-21

722 MethylStar: A fast and robust pipeline for high-throughput analysis of bulk or single-cell WGBS data

Shahryary Dizaji, Y.; Hazarika, R. R.; Johannes, F.

10.1101/2019.12.20.884536 — bioinformatics — Posted on 2019-12-21

723 A full-proteome, interaction-specific characterization of mutational hotspots across human cancers

Chen, S.; Liu, Y.; Zhang, Y.; Wierbowski, S. D.; Lipkin, S. M.; Wei, X.; Yu, H.

10.1101/2019.12.20.885293 — bioinformatics — Posted on 2019-12-21

724 Transfer of antigen-encoding bone marrow under immune-preserving conditions deletes mature antigen-specific B cells in recipients and inhibits antigen-specific antibody production

Brooks, J. F.; Davies, J. M.; Wells, J. W.; Steptoe, R. J.

10.1101/2019.12.20.885343 — immunology — Posted on 2019-12-21

725 DHX9-dependent recruitment of BRCA1 to RNA is required to promote DNA end resection in homologous recombination

Chakraborty, P.; Hiom, K.

10.1101/2019.12.20.884593 — cancer biology — Posted on 2019-12-21

726 Self-regulation of single-stranded DNA wrapping dynamics by E. coli SSB promotes both stable binding and rapid dissociation

Naufer, M. N.; Morse, M.; Möller, G. B.; McIsaac, J.; Rouzina, I.; Beuning, P. J.; Williams, M.

10.1101/2019.12.20.885368 — biophysics — Posted on 2019-12-21

727 Log Transformation Improves Dating of Phylogenies

Mai, U.; Mirarab, S.

10.1101/2019.12.20.885582 — bioinformatics — Posted on 2019-12-21

728 metabolisHMM: Phylogenomic analysis for exploration of microbial phylogenies and metabolic pathways

McDaniel, E. A.; Anantharaman, K.; McMahon, K.

10.1101/2019.12.20.884627 — bioinformatics — Posted on 2019-12-21

729 Vargas: heuristic-free alignment for assessing linear and graph read aligners

Darby, C. A.; Gaddipati, R.; Schatz, M. C.; Langmead, B.

10.1101/2019.12.20.884676 — bioinformatics — Posted on 2019-12-21

730 Optimisation of a Novel Bio-Substrate as a Treatment for Atrophic Age-Related Macular Degeneration.

McCormick, R.; Pearce, I.; Kaye, S.; Haneef, A.

10.1101/2019.12.20.884635 — bioengineering — Posted on 2019-12-21

731 Postnatal expansion, maturation and functionality of MR1 T cells in humans

Swarbrick, G. M.; Gela, A.; Cansler, M. E.; Null, M. D.; Duncan, R. B.; Nemes, E.; Shey, M.; Nsereko, M.; Mayanja-Kizza, H.; Kiguli, S.; Koh, J.; Hanekom, W.; Hatherill, M.; Lancioni, C.; Lewinsohn, D. M.; Scriba, T.; Lewinsohn, D. A.

10.1101/2019.12.20.882746 — immunology — Posted on 2019-12-21

732 Identifying Core Operons in Metagenomic Data

Hu, X.; Friedberg, I.

10.1101/2019.12.20.885269 — bioinformatics — Posted on 2019-12-21

733 Gene network reconstruction using single cell transcriptomic data reveals key factors for embryonic stem cell differentiation

Kim, J.; Jakobsen, S. T.; Natarajan, K. N.; Won, K. J.

10.1101/2019.12.20.884163 — bioinformatics — Posted on 2019-12-21

734 Core-2 O-glycans are required for Galectin-3 interaction with the osteoarthritis related protein lubricin

Flowers, S. A.; Thomsson, K. A.; Ali, L.; Huang, S.; Mthembu, Y.; Regmi, S. C.; Holgersson, J.; Schimdt, T. A.; Rolfson, O.; Bjorkman, L. I.; Sundqvist, M.; Karlsson, A.; Jay, G. D.; Eisler, T.; Krawetz, R.; Karlsson, N. G.

10.1101/2019.12.20.884148 — biochemistry — Posted on 2019-12-21

735 The protective effect of club cell secretory protein (CC-16) on COPD risk and progression: a Mendelian randomisation study

Milne, S.; Li, X.; Hernandez Cordero, A. I.; Yang, C. X.; Cho, M. H.; Beaty, T. H.; Ruczinski, I.; Hansel, N. N.; Bosse, Y.; Brandsma, C.-A.; Sin, D. D.; Obeidat, M.

10.1101/2019.12.20.885384 — genomics — Posted on 2019-12-21

736 Memory sequencing reveals heritable single cell gene expression programs associated with distinct cellular behaviors

Shaffer, S. M.; Emert, B. L.; Reyes-Hueros, R.; Cote, C.; Harmange, G.; Sizemore, A. E.; Gupte, R.; Torre, E.; Singh, A.; Bassett, D. S.; Raj, A.

10.1101/379016 — systems biology — Posted on 2019-12-21

737 Perturbing proteomes at single residue resolution using base editing

Despres, P. C.; Dube, A. K.; Seki, M.; Yachie, N.; Landry, C. R.

10.1101/677203 — synthetic biology — Posted on 2019-12-21

738 Zebrafish dorsolateral habenula is required for updating learned behaviors

Palumbo, F.; Serneels, B.; Pelgrims, R.; Yaksi, E.

10.1101/802256 — neuroscience — Posted on 2019-12-21

739 Transcriptomic changes due to early, chronic ethanol exposure during cortical development implicates arealization, cell-type specification, Axon Guidance and Synaptogenesis as primary determinants of Fetal Alcohol Spectrum Disorders

Fischer, M.; Chander, P.; Kang, H.; Weick, J. P.

10.1101/784793 — neuroscience — Posted on 2019-12-21

740 Acid Experimental Evolution of the Extremely Halophilic Archaeon Halobacterium sp. NRC-1 Selects Mutations Affecting Arginine Transport and Catabolism

Kunka, K. S.; Griffith, J. M.; Holdener, C.; Bischof, K. M.; Li, H.; DasSarma, P.; DasSarma, S.; Slonczewski, J. L.

10.1101/662882 — genetics — Posted on 2019-12-21

741 Mitochondrial DNA Repair in an Arabidopsis thaliana Uracil N-Glycosylase Mutant

Wynn, E. L.; Purfeerst, E.; Christensen, A. C.

10.1101/427500 — genetics — Posted on 2019-12-21

742 Adaptive evolution shapes the present-day distribution of the thermal sensitivity of population growth rate

Kontopoulos, D. - G.; Smith, T. P.; Barraclough, T. G.; Pawar, S.

10.1101/712885 — evolutionary biology — Posted on 2019-12-21

743 Large single-locus effects for maturation timing are mediated via body condition in Atlantic salmon

Debes, P. V.; Piavchenko, N.; Ruokolainen, A.; Ovaskainen, O.; Moustakas-Verho, J. E.; Parre, N.; Aykanat, T.; Erkinaro, J.; Primmer, C. R.

10.1101/780437 — evolutionary biology — Posted on 2019-12-21

744 Constraints and limitations on decoding positional information: the Bicoid case-study

Tran, H.; Walczak, A. M.; Dostatni, N.

10.1101/728840 — developmental biology — Posted on 2019-12-21

745 Global ocean resistome revealed: exploring Antibiotic Resistance Genes (ARGs) abundance and distribution on TARA oceans samples through machine learning tools

Cuadrat, R. R. d. C.; Sorokina, M.; Andrade, B. G.; Goris, T.; Davila, A. M. R.

10.1101/765446 — bioinformatics — Posted on 2019-12-21

746 Great tits in noisy territories and avoiding overlapping respond stronger to territorial intruders.

Akcay, C.; Porsuk, Y. K.; Avsar, A.; Cabuk, D.; Bilgin, C. C.

10.1101/808733 — animal behavior and cognition — Posted on 2019-12-21

747 A major locus controls a biologically active pheromone component in Heliconius melpomene

Byers, K. J. R. P.; Darragh, K.; Musgrove, J.; Abondano Almeida, D.; Fernanda Garza, S.; Warren, I. A.; Rastas, P.; Kucka, M.; Chan, Y. F.; Merrill, R. M.; Schulz, S.; McMillan, W. O.; Jiggins, C. D.

10.1101/739037 — evolutionary biology — Posted on 2019-12-21

748 Distinguishing coalescent models - which statistics matter most?

Freund, F.; Siri-Jegousse, A.

10.1101/679498 — evolutionary biology — Posted on 2019-12-21

749 Differential side-effects of Bacillus thuringiensis bioinsecticide on non-target Drosophila flies

Babin, A.; Nawrot-Esposito, M.-P.; Gallet, A.; Gatti, J.-L.; Poirie, M.

10.1101/541847 — ecology — Posted on 2019-12-21

750 Can we assume the gene expression profile as a proxy for signaling network activity?

Piran, M.; Karbalaei, R.; Piran, M.; Aldahdooh, J.; Mirzaie, M.; Ansari-Pour, N.; Tang, J.; Jafari, M.

10.1101/643866 — systems biology — Posted on 2019-12-21

751 Metabolic recovery and compensatory shell growth of juvenile Pacific geoduck Panopea generosa following short-term exposure to acidified seawater

Gurr, S. J.; Vadopalas, B.; Roberts, S. B.; Putnam, H. M.

10.1101/689745 — physiology — Posted on 2019-12-21

752 An unbiased template of the Drosophila brain and ventral nerve cord

Bogovic, J. A.; Otsuna, H.; Heinrich, L.; Ito, M.; Jeter, J.; Meissner, G. W.; Nern, A.; Colonell, J.; Malkesman, O.; Ito, K.; Saalfeld, S.

10.1101/376384 — neuroscience — Posted on 2019-12-21

753 Resolving multisensory and attentional influences across cortical depth in sensory cortices

Gau, R.; Bazin, P.-L.; Trampel, R.; Turner, R.; Noppeney, U.

10.1101/548933 — neuroscience — Posted on 2019-12-21

754 A novel phyllosphere resident Protomyces species that interacts with the Arabidopsis immune system.

Wang, K.; Sipilä, T.; Rajaraman, S.; Safronov, O.; Laine, P.; Auzane, A.; Mari, A.; Auvinen, P.; Paulin, L.; Kemen, E.; Salojärvi, J.; Overmyer, K.

10.1101/594028 — microbiology — Posted on 2019-12-21

755 Common gardens in teosintes reveal the establishment of a syndrome of adaptation to altitude

Fustier, M.-A.; Martinez-Ainsworth, N. E.; Aguirre-Liguori, J.; Venon, A.; Corti, H.; Rousselet, A.; Dumas, F.; Dittberner, H.; Camarena, M. G.; Grimanelli, D.; Ovaskainen, O.; Falque, M.; Moreau, L.; de Meaux, J.; Montes-Hernandez, S.; Eguiarte, L. E.; Vigouroux, Y.; Manicacci, D.; Tenaillon, M. I.

10.1101/563585 — evolutionary biology — Posted on 2019-12-21

756 Studies of NH4+ and NO3- uptake ability of subalpine plants and resource-use strategy identified by their functional traits.

Legay, N.; Grassein, F.; Arnoldi, C.; Raphael, S.; Philippe, L.; Lavorel, S.; Clement, J.-C.

10.1101/372235 — ecology — Posted on 2019-12-21

757 FAIM opposes stress-induced loss of viability and blocks the formation of protein aggregates

Kaku, H.; Rothstein, T. L.

10.1101/569988 — cell biology — Posted on 2019-12-21

758 Horizontal gene transfer of the pirAB genes responsible for Acute Hepatopancreatic Necrosis Disease (AHPND) turns a non-Vibrio strain into an AHPND-positive pathogen

Muthukrishnan, S.; Defoirdt, T.; Mohamed Din, M. S.; Md Yassin, I. S.; Md Yusoff, F.; Mohd Ikhsan, N. F.

10.1101/2019.12.20.884320 — microbiology — Posted on 2019-12-20

759 Genetic background and diet affect brown adipose gene co-expression - metabolic associations

Carson, C.; Lawson, H.

10.1101/2019.12.20.884197 — genomics — Posted on 2019-12-20

760 Study on Spatial-temporal Variation of Atmospheric Pollution in China between 2014 and 2019

peng, g.

10.1101/2019.12.20.884346 — ecology — Posted on 2019-12-20

761 The Effect of New Nurses' Clinical Competence on Career Adaptation

Lee, K. H.; LEE, M.

10.1101/2019.12.20.884270 — scientific communication and education — Posted on 2019-12-20

762 Evolutionary conservation and multilevel post-translational control of S-adenosyl-homocysteine-Hydrolase in land plants

Alegre, S.; Pascual, J.; Trotta, A.; Angeleri, M.; Rahikainen, M.; Brosche, M.; Moffatt, B.; Kangasjarvi, S.

10.1101/2019.12.20.884296 — plant biology — Posted on 2019-12-20

763 Effect of intensity of agronomic practices on the yield of two breeding types of winter oilseed rape cultivars

Wojtowicz, M.; Wojtowicz, A.; Jajor, E.; Korbas, M.; Wielebski, F.

10.1101/2019.12.20.884304 — plant biology — Posted on 2019-12-20

764 A Late Cretaceous Lonchodectid?

Albuquerque, C.

10.1101/2019.12.17.879783 — paleontology — Posted on 2019-12-20

765 Scrambling the skin: Simulated skin re-arrangement using apparent motion

Seizova-Cajic, T.; Ludvigsson, S.; Sourander, B.; Popov, M.; Taylor, J. L.

10.1101/2019.12.20.884239 — neuroscience — Posted on 2019-12-20

766 Oligodendrocyte-derived exosomes promote axonal transport and axonal long-term maintenance

Frühbeis, C.; Kuo-Elsner, W. P.; Barth, K.; Peris, L.; Tenzer, S.; Möbius, W.; Werner, H.; Nave, K.-A.; Fröhlich, D.; Krämer-Albers, E.-M.

10.1101/2019.12.20.884171 — neuroscience — Posted on 2019-12-20

767 PolyQ-independent toxicity associated with novel translational products from CAG repeat expansions

Rudich, P.; Watkins, S.; Lamitina, T.

10.1101/2019.12.20.884254 — neuroscience — Posted on 2019-12-20

768 Stimulus-choice (mis)alignment in primate MT cortex

Zhao, Y.; Yates, J. L.; Levi, A. J.; Huk, A. C.; Park, I. M.

10.1101/2019.12.20.884189 — neuroscience — Posted on 2019-12-20

769 Functional NHE1 Expression is Critical to Blood Brain Barrier Integrity and Sumatriptan Blood to Brain Uptake

Largent-Milnes, T.; Liktor-Busa, E.; Blawn, K. T.; Kellohen, K. L.; Wiese, B. M.; Verkhovsky, V.; Wahl, J.; Vivek, A.; Davis, T. P.; Vanderah, T. W.

10.1101/2019.12.20.884247 — neuroscience — Posted on 2019-12-20

770 A four-step regulatory cascade controls bistable transfer competence development of the integrative and conjugative element ICEclc in Pseudomonas

van der Meer, J. R.; Carraro, N.; Richard, X.; Sulser, S.; Delavat, F.; Mazza, C.

10.1101/2019.12.20.884213 — microbiology — Posted on 2019-12-20

771 Translational profiling of macrophages infected with Leishmania donovani identifies mTOR- and eIF4A-sensitive immune-related transcripts

Chaparro, V.; Leroux, L.-P.; Masvidal, L.; Lorent, J.; Graber, T. E.; Zimmermann, A.; Arango Duque, G.; Descoteaux, A.; Alain, T.; Larsson, O.; Jaramillo, M.

10.1101/2019.12.20.884338 — immunology — Posted on 2019-12-20

772 Intracellular DNA replication and differentiation of Trypanosoma cruzi is asynchronous within individual host cells in vivo at all stages of infection

Taylor, M. C.; Ward, A.; Olmo, F.; Jayawardhana, S.; Francisco, A. F.; Lewis, M. D.; Kelly, J. M.

10.1101/2019.12.20.884221 — microbiology — Posted on 2019-12-20

773 Rethinking causality and data complexity in brain lesion-behaviour inference and its implications for lesion-behaviour modelling

Sperber, C.

10.1101/2019.12.17.878355 — neuroscience — Posted on 2019-12-20

774 Staphylococcus aureus staphyloxanthin expression is not controlled by Hfq

Liu, W.; Boudry, P.; Bohn, C.; Bouloc, P.

10.1101/2019.12.17.876839 — microbiology — Posted on 2019-12-20

775 Biasing HER4 Tyrosine Kinase Signaling with Antibodies: Induction of Cell Death by Antibody-Dependent HER4 Intracellular Domain Trafficking

Lanotte, R.; Garambois, V.; Gaborit, N.; Larbouret, C.; Musnier, A.; Martineau, P.; Pelegrin, A.; Chardes, T.

10.1101/2019.12.20.883819 — cancer biology — Posted on 2019-12-20

776 Compensatory guaiacyl lignin biosynthesis at the expense of syringyl lignin in 4CL1-knockout poplar

Tsai, C.-J.; Xu, P.; Xue, L.-J.; Hu, H.; Nyamdari, B.; Naran, R.; Zhou, X.; Goeminne, G.; Gao, R.; Gjersing, E.; Dahlen, J.; Pattathil, S.; Hahn, M. G.; Davis, M.; Ralph, J.; Boerjan, W. A.; Harding, S. A.

10.1101/2019.12.20.885350 — plant biology — Posted on 2019-12-20

777 Determining insulin sensitivity from glucose tolerance tests in Iberian and Landrace pigs

Rodriguez-Lopez, J. M.; Lachica, M.; Gonzalez-Valero, L.; Fernandez-Figares, I.

10.1101/2019.12.20.884056 — physiology — Posted on 2019-12-20

778 Composition is the core driver of the language-selective network

Mollica, F.; Siegelman, M.; Diachek, E.; Piantadosi, S. T.; Mineroff, Z.; Futrell, R.; Kean, H.; Qian, P.; Fedorenko, E.

10.1101/436204 — neuroscience — Posted on 2019-12-20

779 A single-cell transcriptomic atlas of the adult Drosophila ventral nerve cord

Allen, A. M.; Neville, M. C.; Birtles, S.; Croset, V.; Treiber, C. D.; Waddell, S.; Goodwin, S. F.

10.1101/2019.12.20.883884 — neuroscience — Posted on 2019-12-20

780 Polycomb-mediated repression compensates for loss of postnatal DNA methylation in excitatory neurons

Li, J.; Pinto-Duarte, A.; Zander, M.; Lai, C.-Y.; Osteen, J.; Fang, L.; Luo, C.; Lucero, J. D.; Gomez-Castanon, R.; Nery, J. R.; Silva-Garcia, I.; Pang, Y.; Sejnowski, T. J.; Powell, S. B.; Ecker, J. R.; Mukamel, E. A.; Behrens, M. M.

10.1101/2019.12.20.883694 — neuroscience — Posted on 2019-12-20

781 Increasing motor skill acquisition by driving theta-gamma coupling

Akkad, H.; Dupont-Hadwen, J.; Frese, A.; Tetkovic, I.; Barrett, L.; Bestmann, S.; Stagg, C. J.

10.1101/2019.12.20.883926 — neuroscience — Posted on 2019-12-20

782 A sub+ cortical fMRI-based surface parcellation

Lewis, J. D.; Bezgin, G.; Fonov, V. S.; Collins, D. L.; Evans, A. C.

10.1101/2019.12.20.883553 — neuroscience — Posted on 2019-12-20

783 TIP5 safeguards genome architecture of ground-state pluripotent stem cells

Dalcher, D.; Tan, J. Y.; Bersaglieri, C.; Pena-Hernandez, R.; Vollenweider, E.; Zeyen, S.; Schmid, M. W.; Bianchi, V.; Butz, S.; Kuzyakiv, R.; Baubec, T.; Marques, A. C.; Santoro, R.

10.1101/2019.12.20.882282 — molecular biology — Posted on 2019-12-20

784 HSI2/VAL1 and HSL1/VAL2 function redundantly to regulate seed dormancy by controlling DOG1 expression in Arabidopsis

Allen, R. D.; Chen, N.; Wang, H.; Abdelmageed, H.; Veerappan, V.; Tadege, M.

10.1101/2019.12.20.885392 — molecular biology — Posted on 2019-12-20

785 Nuclear upregulation of PI3K p110β correlates with increased rRNA transcription in endometrial cancer cells

Mazloumi Gavgani, F.; Karlsson, T.; Tangen, I. L.; Papdine Morovicz, A.; Smith Arnesen, V.; Turcu, D.; Krakstad, C.; Guillermet-Guibert, J.; Lewis, A. E.

10.1101/2019.12.20.884122 — molecular biology — Posted on 2019-12-20

786 Spatial Areas of Genotype Probability (SPAG): predicting the spatial distribution of adaptive genetic variants under future climatic conditions

Rochat, E.; Joost, S.

10.1101/2019.12.20.884114 — genetics — Posted on 2019-12-20

787 Sequence heterochrony led to a gain of functionality in an immature stage of the central complex: a fly-beetle insight

Farnworth, M. S.; Eckermann, K. N.; Bucher, G.

10.1101/2019.12.20.883900 — evolutionary biology — Posted on 2019-12-20

788 Inferring the Demographic History of Inbred Species from Genome-Wide SNP Frequency Data

Blischak, P. D.; Barker, M.; Gutenkunst, R. N.

10.1101/2019.12.20.881474 — evolutionary biology — Posted on 2019-12-20

789 The spatial Muller's ratchet: surfing of deleterious mutations during range expansion

Foutel-Rodier, F.; Etheridge, A.

10.1101/2019.12.20.883975 — evolutionary biology — Posted on 2019-12-20

790 SPARTA imputes sparse single-cell ChIP-seq signals leveraging epigenomic bulk ENCODE data

Albrecht, S.; Andreani, T.; Andrade-Navarro, M. A.; Fontaine, J.-F.

10.1101/2019.12.20.883983 — bioinformatics — Posted on 2019-12-20

791 Empirical dynamic modeling reveals ecological drivers of dengue dynamics

Nova, N.; Deyle, E. R.; Shocket, M.; MacDonald, A. J.; Childs, M.; Rypdal, M.; Sugihara, G.; Mordecai, E. A.

10.1101/2019.12.20.883363 — ecology — Posted on 2019-12-20

792 Modelling the emergence of whisker barrels

James, S. S.; Krubitzer, L. A.; Wilson, S. P.

10.1101/2019.12.20.884106 — developmental biology — Posted on 2019-12-20

793 Investigating mechanisms of polarized light sensitivity in the small white butterfly Pieris rapae

Blake, A. J.; Hahn, G. S.; Grey, H.; Kwok, S.; McIntosh, D.; Gries, G.

10.1101/2019.12.19.883272 — animal behavior and cognition — Posted on 2019-12-20

794 Signature activities of 20S proteasome include degradation of the ubiquitin-tag with the protein under hypoxia

Sahu, I.; Mali, S. M.; Sulkshane, P.; Rozenberg, A.; Xu, C.; Morag, R.; Sahoo, M. P.; Singh, S. K.; Ding, Z.; Wang, Y.; Day, S.; Cong, Y.; Kleifeld, O.; Brik, A.; Glickman, M. H.

10.1101/2019.12.20.883942 — biochemistry — Posted on 2019-12-20

795 The role of the anterior intraparietal sulcus and the lateral occipital cortex in fingertip force scaling and weight perception during object lifting

van Polanen, V.; Rens, G.; Davare, M.

10.1101/2019.12.20.883918 — neuroscience — Posted on 2019-12-20

796 Glutamatergic modulation of auditory cortex connectivity with attentional brain networks in unpredictable perceptual environment

Kompus, K.; Volehaugen, V.; Craven, A.; Specht, K.

10.1101/2019.12.20.884049 — neuroscience — Posted on 2019-12-20

797 Testing relationships between multimodal modes of brain structural variation and age, sex and polygenic scores for neuroticism in children and adolescents

Norbom, L. B.; Rokicki, J.; van der Meer, D.; Alnaes, D.; Doan, N. T.; Moberget, T.; Kaufmann, T.; Andreassen, O.; Westlye, L. T.; Tamnes, C. K.

10.1101/2019.12.20.883959 — neuroscience — Posted on 2019-12-20

798 Whole-body imaging of neural and muscle activity during behavior in Hydra: bidirectional effects of osmolarity on contraction bursts

Yamamoto, W.; Yuste, R.

10.1101/2019.12.20.883835 — neuroscience — Posted on 2019-12-20

799 Testing the adaptive decoupling hypothesis in a hypermetaphorphic and sexually dimorphic insect

Herrig, D. K.; Vertacnik, K. L.; Linnen, C. R.

10.1101/2019.12.20.882803 — evolutionary biology — Posted on 2019-12-20

800 VPS41 recessive mutation causes ataxia and dystonia with retinal dystrophy and mental retardation by inhibiting HOPS function and mTORC1 signaling

van der Welle, R. E. N.; Jobling, R.; Burns, C.; Sanza, P.; ten Brink, C.; Fasano, A.; Chen, L.; Zwartkruis, F. J.; Zwakenberg, S.; Griffin, E. F.; van der Beek, J.; Veenendaal, T.; Liv, N.; Blaser, S.; Sepulveda, C.; Lozano, A. M.; Yoon, G.; Asensio, C. S.; Caldwell, G. A.; Caldwell, K. A.; Chitayat, D.; Klumperman, J.

10.1101/2019.12.18.867333 — cell biology — Posted on 2019-12-20

801 Energy-based Graph Convolutional Networks for Scoring Protein Docking Models

Cao, Y.; Shen, Y.

10.1101/2019.12.19.883371 — bioinformatics — Posted on 2019-12-20

802 Platelet proteolytic machinery assessment in Alzheimer's Disease

Muriu, R. G.; Sage, J. M.; Agbas, A.

10.1101/760116 — neuroscience — Posted on 2019-12-20

803 Image Reconstruction Reveals the Impact of Aging on Face Perception

Chang, C.-H.; Nemrodov, D.; Drobotenko, N.; Nestor, A.; Lee, A. C. H.

10.1101/2019.12.20.883215 — neuroscience — Posted on 2019-12-20

804 Faster than the brain's speed of light: Retinocortical interactions differ in high frequency activity when processing darks and lights

Westner, B. U.; Dalal, S. S.

10.1101/153551 — neuroscience — Posted on 2019-12-20

805 Epiphytic Microbiome of Grapes Berries Varies Between Phenological Timepoints, Growing Seasons and Regions

Hall, M. E.; O'Bryon, I. G.; Wilcox, W. F.; Osier, M. V.; Cadle-Davidson, L.

10.1101/2019.12.20.884502 — microbiology — Posted on 2019-12-20

806 High-dimensional analysis reveals a distinct population of adaptive-like tissue-resident NK cells in human lung

Marquardt, N.; Scharenberg, M.; Mold, J. E.; Hard, J.; Kekalainen, E.; Buggert, M.; Nguyen, S.; Wilson, J. N.; Al-Ameri, M.; Ljunggren, H.-G.; Michaelsson, J.

10.1101/2019.12.20.883785 — immunology — Posted on 2019-12-20

807 Recurrent acquisition of alien ribotoxin encoding genes by insect genomes

Lapadula, W. J.; Mascotti, M. L.; Juri Ayub, M.

10.1101/2019.12.20.880922 — evolutionary biology — Posted on 2019-12-20

808 Soil variation response is mediated by growth trajectories rather than functional traits in a widespread pioneer Neotropical tree

Levionnois, S.; Tysklind, N.; Nicolini, E.; Ferry, B.; Troispoux, V.; Le Moguedec, G.; Morel, H.; Stahl, C.; Coste, S.; Caron, H.; Heuret, P.

10.1101/351197 — ecology — Posted on 2019-12-20

809 Data-driven algorithm for the diagnosis of behavioral variant frontotemporal dementia

Manera, A.; Dadar, M.; van Swieten, J.; Borroni, B.; Sanchez-Valle, R.; Moreno, F.; LaForce, R.; Graff, C.; Synofzik, M.; Galimberti, D.; Rowe, J.; Masellis, M.; Tartaglia, M. C.; Finger, E.; Vandenberghe, R.; de Mendonca, A.; Tagliavini, F.; Santana, I.; Butler, C.; Gerhard, A.; Danek, A.; Levin, J.; Otto, M.; Frisoni, G.; Ghidoni, R.; Sorbi, S.; Rohrer, J. D.; Ducharme, S.; Collins, D. L.

10.1101/2019.12.19.883462 — neuroscience — Posted on 2019-12-20

810 Spike activity regulates vesicle filling at a glutamatergic synapse

Li, D.; Zhu, Y.; Huang, H.

10.1101/2019.12.20.873083 — neuroscience — Posted on 2019-12-20

811 A genomic view of coral-associated Prosthecochloris and a companion sulfate-reducing bacterium

Chen, Y.-H.; Yang, S.-H.; Tandon, K.; Lu, C.-Y.; Chen, H.-J.; Shih, C.-J.; Tang, S.-L.

10.1101/2019.12.20.883736 — microbiology — Posted on 2019-12-20

812 Sex chromosome and sex locus characterization in the goldfish, Carassius auratus

Wen, M.; Feron, R.; Pan, Q.; Guguin, J.; Jouanno, E.; Herpin, A.; Klopp, C.; Cabau, C.; Zahm, M.; Parinello, H.; Journot, L.; Burgess, S. M.; Omori, Y.; Postlethwait, J.; Schartl, M.; Guiguen, Y.

10.1101/2019.12.20.875377 — genomics — Posted on 2019-12-20

813 Massively parallel, time-resolved single-cell RNA sequencing with scNT-Seq

Qiu, Q.; Hu, P.; Govek, K. W.; Camara, P. G.; Wu, H.

10.1101/2019.12.19.882050 — genomics — Posted on 2019-12-20

814 Sequence read mapping and variant discovery from bovine breed-specific augmented reference graphs

Crysnanto, D.; Pausch, H.

10.1101/2019.12.20.882423 — genomics — Posted on 2019-12-20

815 A modified two-color flow cytometry assay to quantify in-vitro reinvasion and determine invasion phenotypes at low Plasmodium falciparum parasitemia

Ngoh, I. A.; Nota, D. A.; Fru, J. C.; Bojang, F.; Mbye, H.; Amambua-Ngwa, A.

10.1101/2019.12.20.885301 — cell biology — Posted on 2019-12-20

816 Enhancer hijacking determines intra- and extrachromosomal circular MYCN amplicon architecture in neuroblastoma

Helmsauer, K.; Valieva, M.; Ali, S.; Chamorro Gonzalez, R.; Schoepflin, R.; Roeefzaad, C.; Bei, Y.; Dorado Garcia, H.; Rodriguez-Fos, E.; Puiggros, M.; Heinrich, V.; Robson, M.; Kasack, K.; Haase, K.; Kuschel, L. P.; Euskirchen, P.; Rosswog, C.; Toedling, J.; Szymansky, A.; Hertwig, F.; Fischer, M.; Torrents, D.; Eggert, A.; Schulte, J. H.; Mundlos, S.; Henssen, A. G.; Koche, R. P.

10.1101/2019.12.20.875807 — cancer biology — Posted on 2019-12-20

817 Partial loss of colonic primary cilia promotes inflammation and carcinogenesis

10.1101/2019.12.20.871772 — cancer biology — Posted on 2019-12-20

818 Baseline dopamine predicts individual variation in methylphenidate's effects on cognitive motivation

Hofmans, L.; Papadopetraki, D.; van den Bosch, R.; Määttä, J. I.; Froböse, M. I.; Zandbelt, B. B.; Westbrook, A.; Verkes, R.-J.; Cools, R.

10.1101/859637 — neuroscience — Posted on 2019-12-20

819 Mechanistic Basis for Microhomology Identification and Genome Scarring by Polymerase Theta

Carvajal-Garcia, J.; Cho, J.-E.; Carvajal-Garcia, P.; Feng, W.; Wood, R. D.; Sekelsky, J.; Gupta, G. P.; Roberts, S. A.; Ramsden, D. A.

10.1101/2019.12.20.882852 — molecular biology — Posted on 2019-12-20

820 Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease

Winkler, T. W.; Grassmann, F.; Brandl, C.; Kiel, C.; Guenther, F.; Strunz, T.; Weidner, L.; Zimmermann, M. E.; Korb, C. A.; Poplawski, A.; Schuster, A.; Muller-Nuraysid, M.; Peters, A.; Rauscher, F. G.; Elze, T.; Horn, K.; Scholz, M.; Canadas-Garre, M.; McKnight, A. J.; Quinn, N.; Hogg, R. E.; Kuechenhoff, H.; Heid, I. M.; Stark, K. J.; Weber, B. H.

10.1101/2019.12.20.883801 — genetics — Posted on 2019-12-20

821 mtor Haploinsufficiency Ameliorates Renal Cyst Formation in Adult Zebrafish tmem67 Mutants

Zhu, P.; Qiu, Q.; Harris, P. C.; Xu, X.; Lin, X.

10.1101/2019.12.20.883710 — genetics — Posted on 2019-12-20

822 A neuronal thermostat controls membrane fluidity in C. elegans

Casanueva, O.; Chauve, L.; Murdoch, S.; Masoudzadeh, F.; Hodge, F.; Lopez-Clavijo, A.; Okkenhaug, H.; Wingett, S.; Wakelam, M.; Kleigrewe, K.

10.1101/2019.12.20.882514 — genetics — Posted on 2019-12-20

823 Ankylosis homologue (ANKH) controls extracellular citrate and pyrophosphate homeostasis and affects bone mechanical performance

Szeri, F.; Lundkvist, S.; Donnelly, S.; Engelke, U. F. H.; Rhee, K.; Williams, C.; Sundberg, J. P.; Wevers, R. A.; Tomlinson, R. E.; Jansen, R. S.; van de Wetering, K.

10.1101/2019.12.20.883223 — developmental biology — Posted on 2019-12-20

824 The Low-Cost, Semi-Automated Shifter Microscope Stage Transforms Speed and Robustness of Manual Protein Crystal Harvesting

Wright, N.; von Delft, F.; Collins, P.; Talon, R.; Nelson, E.; Koekemoer, L.; Ye, M.; Nowak, R.; Newman, J.; Ng, J. T.; Mitrovich, N.; Wiggers, H.

10.1101/2019.12.20.875674 — biophysics — Posted on 2019-12-20

825 prewas: Data pre-processing for more informative bacterial GWAS

Saund, K.; Lapp, Z.; Thiede, S. N.; Pirani, A.; Snitkin, E. S.

10.1101/2019.12.20.873158 — bioinformatics — Posted on 2019-12-20

826 Overcoming high nanopore basecaller error rates for DNA storage via basecaller-decoder integration and convolutional codes

Chandak, S.; Neu, J.; Tatwawadi, K.; Mardia, J.; Lau, B.; Kubit, M.; Hulett, R.; Griffin, P.; Wootters, M.; Weissman, T.; Ji, H.

10.1101/2019.12.20.871939 — bioengineering — Posted on 2019-12-20

827 Extensive Mammalian Germline Genome Engineering

10.1101/2019.12.17.876862 — synthetic biology — Posted on 2019-12-20

828 Protein Quality Control is a Risk Factor and Therapeutic Target in Toxin-Induced Biliary Atresia

Zhao, X.; Lorent, K.; Escobar-Zarate, D.; Rajagopalan, R.; Loomes, K.; Gillespie, K.; Mesaros, C.; Estrada, M.; Blair, I.; Winkler, J.; Spinner, N.; Devoto, M.; Pack, M.

10.1101/821967 — pathology — Posted on 2019-12-20

829 Frontopolar cortex is a mediator of network modularity in the primate brain

Wu, Z.; Ainsworth, M.; Bell, A. H.; Buckley, M. J.

10.1101/2019.12.20.882837 — neuroscience — Posted on 2019-12-20

830 Quantifying and modelling non-local information processing of associative brain regions

Balkenhol, J.; Prada, J.; Ehrenreich, H.; Grohmann, J.; Kistowski, J.; Wojcik, S.; Blum, R.; Kounev, S.; Dandekar, T.

10.1101/2019.12.19.883124 — neuroscience — Posted on 2019-12-20

831 Wt1 positive neurons in the hindbrain are essential for respiration

Schnerwitzki, D.; Hayn, C.; Perner, B.; Englert, C.

10.1101/2019.12.20.884361 — neuroscience — Posted on 2019-12-20

832 Alpha synuclein aggresomes inhibit ciliogenesis and multiple functions of the centrosome

Iqbal, A.; Baldrighi, M.; Murdoch, J. N.; Fleming, A.; Wilkinson, C. J.

10.1101/2019.12.20.884643 — neuroscience — Posted on 2019-12-20

833 CyTOF reveals phenotypically-distinct human blood neutrophil populations differentially correlated with melanoma stage

Zhu, Y. P.; Eggert, T.; Araujo, D. J.; Vijayanand, P.; Ottensmeier, C.; HEDRICK, C.

10.1101/826644 — immunology — Posted on 2019-12-20

834 The causal role of circulating vitamin D concentrations in human complex traits and diseases: a large-scale Mendelian randomization study

Jiang, X.; Ge, T.; Chen, C.-Y.

10.1101/677922 — genetics — Posted on 2019-12-20

835 Conserved epigenetic regulatory logic infers genes governing cell identity

Shim, W. J.; Sinniah, E.; Xu, J.; Vitrinel, B.; Alexanian, M.; Andreoletti, G.; Shen, S.; Balderson, B.; Peng, G.; Jing, N.; Sun, Y.; Chhabra, Y.; Wang, Y.; Tam, P.; Smith, A.; Piper, M.; Christiaen, L.; Nguyen, Q.; Boden, M.; Palpant, N.

10.1101/635516 — cell biology — Posted on 2019-12-20

836 Repression of LKB1 by miR-17~92 sensitizes MYC-dependent lymphoma to biguanide treatment

Izreig, S.; Gariepy, A.; Donayo, A. O.; Bridon, G.; Avizonis, D.; Sheldon, R. D.; Laister, R.; Minden, M. D.; Johnson, N. A.; Williams, K. S.; Rudoltz, M. S.; Duchaine, T. F.; Yoo, S.; Pollak, M. N.; Jones, R. G.

10.1101/2019.12.20.883025 — cancer biology — Posted on 2019-12-20

837 The effectiveness of glass beads for plating cell cultures

Prusokas, A.; Hawkins, M.; Nieduszynski, C.; Retkute, R.

10.1101/241752 — biophysics — Posted on 2019-12-20

838 Release of human TFIIB from actively transcribing complexes is triggered upon synthesis of 7 nt and 9 nt RNAs

Ly, E.; Powell, A. E.; Goodrich, J.; Kugel, J.

10.1101/2019.12.19.882902 — biochemistry — Posted on 2019-12-20

839 Homologous laminar organization of the mouse and human subiculum

Bienkowski, M. S.; Sepehrband, F.; Kurniawan, N. D.; Stanis, J.; Korobkova, L.; Khanjani, N.; Hintiryan, H.; Miller, C. A.; Dong, H.-W.

10.1101/2019.12.20.883074 — neuroscience — Posted on 2019-12-20

840 Open the LID: LXRα regulates ChREBPα transactivity in a target gene-specific manner through an agonist-modulated LBD-LID interaction

Fan, Q.; Norgaard, R. C.; Grytten, I.; Ness, C. M.; Lucas, C.; Vekterud, K.; Soedling, H.; Matthews, J.; Lemma, R. B.; Gabrielsen, O. S.; Bindesboll, C.; Ulven, S. M.; Nebb, H. I.; Gronning-Wang, L. M.; Saether, T.

10.1101/2019.12.20.869974 — molecular biology — Posted on 2019-12-20

841 Zygote morphogenesis but not the establishment of cell polarity in Plasmodium berghei is controlled by the small GTPase, RAB11A

Waters, A. P.; Patil, H. P.; Dickens, N.; Hughes, K.; Philip, N.; Lemgruber Soares, L.

10.1101/811802 — cell biology — Posted on 2019-12-20

842 Microbial microdroplet culture system (MMC): an integrated platform for automated, high-throughput microbial cultivation and adaptive evolution

Jian, X.; Guo, X.; Wang, J.; Tan, Z. L.; Xing, X.-h.; Wang, L.; Zhang, C.

10.1101/2019.12.19.883561 — bioengineering — Posted on 2019-12-20

843 Enzyme capacity-based genome scale modelling of CHO cells

Yeo, H. C.; Hong, J.; Lakshmanan, M.; Lee, D.-Y.

10.1101/2019.12.19.883652 — systems biology — Posted on 2019-12-20

844 Perceptual weighting of binaural lateralization cues across frequency bands

Ahrens, A.; Joshi, S. N.; Epp, B.

10.1101/2019.12.20.873059 — neuroscience — Posted on 2019-12-20

845 Chromatin reorganization during myoblast differentiation involves the caspase-dependent removal of SATB2

Bell, R. A. V.; Al-Khalaf, M. H.; Brunette, S.; Chu, A.; Dechant, G.; Apostolova, G.; Dilworth, J.; Megeney, L. A.

10.1101/2019.12.19.883579 — molecular biology — Posted on 2019-12-20

846 Do footbath disinfectants modify the dynamics of the skin microbiota in dairy cattle affected by digital dermatitis?

Ariza, J. M.; Dopfer, D.; Anklam, K.; Labrut, S.; Oberle, K.; Bareille, N.; Relun, A.; Guatteo, R.

10.1101/2019.12.20.882787 — microbiology — Posted on 2019-12-20

847 High-polyphenol extracts from Sorghum bicolor attenuate replication of Legionella pneumophila within RAW 264.7 macrophages

Gilchrist, A. M.; Smolensky, D.; Cox, S.; Perumal, R.; Noronha, L. E.; Shames, S. R.

10.1101/2019.12.19.883249 — microbiology — Posted on 2019-12-20

848 Peripheral nerve resident macrophages are microglia-like cells with tissue-specific programming

Wang, P. L.; Yim, A. K.; Kim, K.; Avey, D.; Czepielewski, R. S.; Colonna, M.; Milbrandt, J.; Randolph, G. J.

10.1101/2019.12.19.883546 — immunology — Posted on 2019-12-20

849 A map of transcriptional heterogeneity and regulatory variation in human microglia

Young, A.; Kumasaka, N.; Calvert, F.; Hammond, T. R.; Knights, A. J.; Panousis, N.; Schwartzentruber, J.; Liu, J.; Kundu, K.; Segel, M.; Murphy, N.; McMurran, C. E.; Bulstrode, H.; Correia, J.; Budohoski, K. P.; Joannides, A.; Guilfoyle, M. R.; Trivedi, R.; Kirollos, R.; Morris, R.; Garnett, M. R.; Fernandes, H.; Timofeev, I.; Jalloh, I.; Holland, K.; Mannion, R.; Mair, R.; Watts, C.; Price, S. J.; Kirkpatrick, P. J.; Santarius, T.; Soranzo, N.; Stevens, B.; Hutchinson, P. J.; Franklin, R. J.; Gaffney, D. J.

10.1101/2019.12.20.874099 — genomics — Posted on 2019-12-20

850 From village to globe: A dynamic real-time map of African fields through PlantVillage

Kehs, A.; McCloskey, P.; Chelal, J.; Morr, D.; Amakove, S.; Plimo, B.; Mayieka, J.; Ntango, G.; Nyongesa, K.; Pamba, L.; Jeptoo, M.; Mugo, J.; Tsuma, M.; Onyango, W.; Hughes, D.

10.1101/2019.12.19.882936 — ecology — Posted on 2019-12-20

851 Optimization and functionalization of red-shifted rhodamine dyes

Grimm, J. B.; Tkachuk, A. N.; Choi, H.; Mohar, B.; Falco, N.; Patel, R.; Lippincott-Schwartz, J.; Brown, T. A.; Lavis, L. D.

10.1101/2019.12.20.881227 — cell biology — Posted on 2019-12-20

852 Computationally Enhanced Quantitative Phase Microscopy Reveals Autonomous Oscillations in Mammalian Cell Growth

Liu, X.; Oh, S.; Peshkin, L.; Kirschner, M. W.

10.1101/631119 — cell biology — Posted on 2019-12-20

853 Tuft cells restrain pancreatic tumorigenesis through paracrine eicosanoid signaling

DelGiorno, K. E.; Chung, C.-Y.; Maurer, H. C.; Weiser Novak, S.; Giraddi, R. R.; Wang, D.; Naeem, R. F.; Fang, L.; Andrade, L. R.; Lytle, N. K.; Ali, W. H.; Tsui, C.; Gubbala, V. B.; Ridinger-Saison, M.; Ohmoto, M.; O'Connor, C.; Erikson, G.; Shokhirev, M. N.; Urade, Y.; Matsumoto, I.; Vavinskaya, V.; Singh, P. K.; Manor, U.; Olive, K. P.; Wahl, G.

10.1101/2019.12.19.882985 — cancer biology — Posted on 2019-12-20

854 Geometry of Ranked Nearest Neighbour Interchange Space of Phylogenetic Trees

Collienne, L.; Elmes, K.; Fischer, M.; Bryant, D. J.; Gavryushkin, A.

10.1101/2019.12.19.883603 — bioinformatics — Posted on 2019-12-20

855 Learning steers the ontogeny of an efficient hunting sequence in zebrafish larvae.

Lagogiannis, K.; Diana, G.; Meyer, M. P.

10.1101/2019.12.19.883157 — animal behavior and cognition — Posted on 2019-12-20

856 A mathematical model exhibiting the effect of DNA methylation on the stability boundary in cell-fate networks

Chen, T.; Ali Al-Radhawi, M.; Sontag, E.

10.1101/2019.12.19.883280 — systems biology — Posted on 2019-12-20

857 Persistence is an optimal hedging strategy for bacteria in volatile environments

Browning, A. P.; Sharp, J. A.; Mapder, T.; Baker, C. M.; Burrage, K.; Simpson, M. J.

10.1101/2019.12.19.883645 — systems biology — Posted on 2019-12-20

858 Detection of Transient Neurotransmitter Response Using Personalized Neural Networks

Klyuzhin, I. S.; Bevington, C. W. J.; Cheng, J.-C.; Sossi, V.

10.1101/2019.12.19.883017 — neuroscience — Posted on 2019-12-20

859 Categorical signaling of the strongest stimulus by an inhibitory midbrain nucleus

Schryver, H. M.; Straka, M.; Mysore, S. P.

10.1101/2019.12.19.883702 — neuroscience — Posted on 2019-12-20

860 White matter abnormalities across different epilepsy syndromes in adults: an ENIGMA Epilepsy study

Hatton, S. N.; Huynh, K. H.; Bonilha, L.; Abela, E.; Alhusaini, S.; Altmann, A. N.; Alvim, M. K.; Balachandra, A. R.; Bargallo, N.; Bartolini, E.; Bender, B.; Bernasconi, A.; Bernasconi, N.; Bernhardt, B.; Caldairou, B.; Caligiuri, M. E.; Carr, S. J.; Cavalleri, G. L.; Cendes, F.; Concha, L.; Davoodi-Bojd, E.; Desmond, P. M.; Devinsky, O.; Doherty, C. P.; Domin, M.; Duncan, J. S.; Niels, N. K.; Foley, S. F.; Gambardella, A.; Gleichgerrcht, E.; Hamandi, K.; Ishikawa, A.; Keller, S. S.; Kochunov, P. V.; Kotikalapudi, R.; Kreilkamp, B. A.; Kwan, P.; Labate, A.; Langner, S.; Lenge, M.; Liu, M.; Lu

10.1101/2019.12.19.883405 — neuroscience — Posted on 2019-12-20

861 Neural modelling of the semantic predictability gain under challenging listening conditions

Rysop, A.; Schmitt, L.-M.; Obleser, J.; Hartwigsen, G.

10.1101/2019.12.20.872614 — neuroscience — Posted on 2019-12-20

862 fMRI reveals language-specific predictive coding during naturalistic sentence comprehension

Shain, C.; Blank, I. A.; van Schijndel, M.; Schuler, W.; Fedorenko, E.

10.1101/717512 — neuroscience — Posted on 2019-12-20

863 The Potential of Lipolytic Filamentous Fungi Isolated from Landfill Soil as Poly-β-Hydroxybutirate (PHB) Bioplastic Degrader

Yanti, N. A.; Sriwahyuni, E.; Rayani, N.; Muhiddin, N. H.; Ahmad, S. W.

10.1101/2019.12.19.883538 — microbiology — Posted on 2019-12-20

864 Linkage Disequilibrium and Heterozygosity Modulate the Genetic Architecture of Human Complex Phenotypes: Evidence of Natural Selection from GWAS Summary Statistics

Holland, D.; Frei, O.; Desikan, R.; Fan, C. C.; Shadrin, A.; Smeland, O.; Andreassen, O. A.; Dale, A.

10.1101/705285 — genomics — Posted on 2019-12-20

865 Temporal specificity and heterogeneity of the fly immune cells' transcriptional landscape

Cattenoz, P. B.; Sakr, R.; Pavlidaki, A.; Delaporte, C.; Riba, A.; Molina, N.; Hariharan, N.; Mukherjee, T.; Giangrande, A.

10.1101/2019.12.20.871301 — developmental biology — Posted on 2019-12-20

866 Chromosome segregation is driven by joint microtubule sliding action of kinesins KIF4A and EG5

Vukusic, K.; Buđa, R.; Ponjavic, I.; Risteski, P.; Tolic, I. M.

10.1101/863381 — cell biology — Posted on 2019-12-20

867 Expansion and re-classification of the extracytoplasmic function (ECF) σ factor family

Casas-Pastor, D.; Müller, R. R.; Becker, A.; Buttner, M.; Gross, C.; Mascher, T.; Goesmann, A.; Fritz, G.

10.1101/2019.12.11.873521 — bioinformatics — Posted on 2019-12-20

868 One-Pot E. coli Cell-Free Extract for in vitro Expression of Disulfide Bonded Proteins

Dopp, J. L.; Reuel, N. F.

10.1101/2019.12.19.883413 — bioengineering — Posted on 2019-12-20

869 Quantifying and Modelling Transfer Learning in Mice Between Consecutive Training Stages of a Change Detection Task

Magrans de Abril, I.; Garrett, M. E.; Ollerenshaw, D. R.; Groblewski, P. A.; Olsen, S.; Mihalas, S.

10.1101/2019.12.19.883470 — animal behavior and cognition — Posted on 2019-12-20

870 Reconstructing the evolutionary origins of extreme halophilic Archaeal lineages

Feng, Y.; Neri, U.; Gosselin, S.; Louyakis, A. S.; Papke, R. T.; Gophna, U.; Gogarten, J. P.

10.1101/2019.12.19.883488 — microbiology — Posted on 2019-12-20

871 Deep neural network affinity model for BACE inhibitors in D3R Grand Challenge 4

Wang, B.; Ng, H. L.

10.1101/680306 — bioinformatics — Posted on 2019-12-20

872 Telomeric Double Strand Breaks Facilitate Formation of 5' C-Rich Overhangs in G1 Human Cells

Nelson, C. B.; Alturki, T.; Taylor, L.; Maranon, D. G.; Muraki, K.; Murnane, J. P.; Bailey, S. M.

10.1101/720565 — molecular biology — Posted on 2019-12-20

873 Rewired signaling network in T cells expressing the chimeric antigen receptor (CAR)

Dong, R.; Libby, K. A.; Blaeschke, F.; Marson, A.; Vale, R. D.; Su, X.

10.1101/2019.12.19.883496 — immunology — Posted on 2019-12-20

874 Genome-wide survey of tandem repeats by nanopore sequencing shows that disease-associated repeats are more polymorphic in the general population

Mitsuhashi, S.; Frith, M. C.; Matsumoto, N.

10.1101/2019.12.19.883389 — genomics — Posted on 2019-12-20

875 Personalized genealogical history inferred from biobank-scale IBD segments

Naseri, A.; Tang, K.; Geng, X.; Shi, J.; Zhang, J.; Liu, X.; Zhang, S.; Zhi, D.

10.1101/2019.12.19.883108 — genetics — Posted on 2019-12-20

876 Mating-type specific ribosomal proteins control aspects of sexual reproduction in Cryptococcus neoformans

Ianiri, G.; Fang, Y.; Dahlmann, T. A.; Clancey, S. A.; Janbon, G.; Kück, U.; Heitman, J.

10.1101/777102 — genetics — Posted on 2019-12-20

877 A New Ultradian Rhythm Linked to Protein Degradation and Synthesis in Mammalian Cells

Ghenim, L.; Allier, C.; Obeid, P.; Herve, L.; Fortin, J.-Y.; Maxim, B.; Gidrol, X.

10.1101/2019.12.20.882811 — cell biology — Posted on 2019-12-20

878 Bmal1 integrates mitochondrial metabolism and macrophage activation

Lee, C.-H.; Alexander, R.; Liou, Y.-H.; Knudsen, N.; Starost, K.; Xu, C.; Hyde, A.; Liu, S.; Jacobi, D.; Liao, N.-S.

10.1101/2019.12.20.884429 — cell biology — Posted on 2019-12-20

879 Binning unassembled short reads based on k-mer covariance using sparse coding

Kyrgyzov, O.; Prost, V.; Gazut, S.; Farcy, B.; Bruls, T.

10.1101/599332 — bioinformatics — Posted on 2019-12-20

880 Single molecule studies reveal that p53 tetramers dynamically bind response elements containing one or two half sites

Ly, E.; Kugel, J.; Goodrich, J.

10.1101/2019.12.19.883140 — biochemistry — Posted on 2019-12-20

881 Inhibitory control of active expiration by the Botzinger complex in rats

Flor, K. C.; Barnett, W. H.; Karlen-Amarante, M.; Molkov, Y. I.; Zoccal, D. B.

10.1101/2019.12.19.883199 — physiology — Posted on 2019-12-20

882 A comparison of automated and manual co-registration for magnetoencephalography

Houck, J. M.; Claus, E. D.

10.1101/711747 — neuroscience — Posted on 2019-12-20

883 Increased juvenile survival may not be universally linked to longevity: ecological, social and life-history drivers of age-specific mortality in birds

Mourocq, E.; Drobniak, S. M.; Griesser, M.

10.1101/2019.12.18.880682 — evolutionary biology — Posted on 2019-12-20

884 The COP9 Signalosome Suppresses Cardiomyocyte Necroptosis

Xiao, P.; Wang, C.; Lewno, M. T.; Wu, P.; Li, J.; Su, H.; Sternburg, J. O.; Liu, J.; Wang, X.

10.1101/2019.12.19.883322 — cell biology — Posted on 2019-12-20

885 Expression of inhibitory checkpoint ligands by Glioblastoma Multiforme cells and the implications of an enhanced stem cell-like phenotype

Robilliard, L. D.; Joseph, W.; Finlay, G.; Angel, C. E.; Graham, S.

10.1101/2019.12.19.883397 — cell biology — Posted on 2019-12-20

886 TreeSwift: a massively scalable Python tree package

Moshiri, N.

10.1101/325522 — bioinformatics — Posted on 2019-12-20

887 Robust calibration of hierarchical population models for heterogeneous cell populations

Loos, C.; Hasenauer, J.

10.1101/718270 — systems biology — Posted on 2019-12-20

888 Multidimensional analysis and detection of informative features in diffusion MRI measurements of human white matter

Richie-Halford, A.; Yeatman, J.; Simon, N.; Rokem, A.

10.1101/2019.12.19.882928 — neuroscience — Posted on 2019-12-20

889 Short-term Effects of Vagus Nerve Stimulationon Learning and Evoked Activity in AuditoryCortex

Lai, J.; David, S. V.

10.1101/2019.12.19.883165 — neuroscience — Posted on 2019-12-20

890 CerebrA: Accurate registration and manual label correction of Mindboggle-101 atlas for MNI-ICBM152 template

Manera, A. L.; Dadar, M.; Fonov, V.; Collins, D. L.

10.1101/2019.12.19.883330 — neuroscience — Posted on 2019-12-20

891 Engineering recurrent neural networks from task-relevant manifolds and dynamics

Pollock, E.; Jazayeri, M.

10.1101/2019.12.19.883207 — neuroscience — Posted on 2019-12-20

892 Phenotypic Heterogeneity in Particle Size is a Viral Mechanism of Persistence

Li, T.; Li, Z.; Liu, M.; Deans, E. E.; Ivanovic, T.

10.1101/843177 — microbiology — Posted on 2019-12-20

893 Maturation of the human B-cell receptor repertoire with age

Ghraichy, M.; Galson, J. D.; Kovaltsuk, A.; von Niederhaeusern, V.; Pachlopnik Schmid, J.; Recher, M.; Jauch, A.; Miho, E.; Kelly, D. F.; Deane, C. M.; Trueck, J.

10.1101/609651 — immunology — Posted on 2019-12-20

894 Attenuation of cGAS/STING Activity During Mitosis

Uhlorn, B. L.; Gamez, E. R.; Campos, S. K.

10.1101/2019.12.19.883090 — immunology — Posted on 2019-12-20

895 Osteopontin and iCD8α cells promote intestinal intraepithelial lymphocytes homeostasis

Nazmi, A.; Greer, M.; Hoek, K. L.; Piazuelo, M. B.; Weitkamp, J.-H.; Olivares-Villagomez, D.

10.1101/669432 — immunology — Posted on 2019-12-20

896 Mitochondrial DNA Repair in an Arabidopsis thaliana Uracil N-Glycosylase Mutant

Wynn, E. L.; Purfeerst, E.; Christensen, A. C.

10.1101/427500 — genetics — Posted on 2019-12-20

897 Evolutionary genomics of structural variation in Asian rice (Oryza sativa) and its wild progenitor (O. rufipogon)

Kou, Y.; Liao, Y.; Toivainen, T.; Lv, Y.; Tian, X.; Emerson, J. J.; Gaut, B. S.; Zhou, Y.

10.1101/2019.12.19.883231 — evolutionary biology — Posted on 2019-12-20

898 Protein Docking and Steered Molecular Dynamics Reveal Alternative Regulatory Sites on the SERCA Calcium Transporter

Alford, R. F.; Smolin, N.; Young, H. S.; Gray, J. J.; Robia, S. L.

10.1101/2019.12.19.883355 — biophysics — Posted on 2019-12-20

899 Incipient resistance to an effective pesticide results from genetic adaptation and the canalization of gene expression

Yin, X.; Martinez, A. S.; Perkins, A.; Sparks, M. M.; Harder, A. M.; Willoughby, J. R.; Sepulveda, M. S.; Christie, M. R.

10.1101/2019.12.19.882860 — genetics — Posted on 2019-12-20

900 Distinct evolutionary trajectories of V1R clades across mouse species

Miller, C. H.; Sheehan, M. J.; Campbell, P.

10.1101/2019.12.19.883082 — evolutionary biology — Posted on 2019-12-20

901 Phenotypic delay: mechanistic models and their implications for the evolution of resistance to antibiotics

Carballo-Pacheco, M.; Nicholson, M. D.; Lilja, E. E.; Allen, R. J.; Waclaw, B.

10.1101/2019.12.19.883132 — evolutionary biology — Posted on 2019-12-20

902 APSiC: Analysis of Perturbation Screens for the Identification of Novel Cancer Genes

Montazeri, H.; Coto-Llerena, M.; Bianco, G.; Zangeneh, E.; Taha-Mehlitz, S.; Paradiso, V.; Srivatsa, S.; de Weck, A.; Roma, G.; Lanzafame, M.; Bolli, M.; Beerenwinkel, N.; von Flüe, M.; Terracciano, L. M.; Piscuoglio, S.; Ng, C. K.

10.1101/807248 — genomics — Posted on 2019-12-20

903 Low costs of adaptation to dietary restriction

Moger-Reischer, R. Z.; Snider, E. V.; McKenzie, K. L.; Lennon, J. T.

10.1101/2019.12.19.883058 — evolutionary biology — Posted on 2019-12-20

904 Cell type- and stage-specific expression of Otx2 is coordinated by a cohort of transcription factors and multiple cis-regulatory modules in the retina

Chan, C.; Lonfat, N.; Zhao, R.; Davis, A.; Li, L.; Wu, M.-R.; Lin, C.-H.; Ji, Z.; Cepko, C.; Wang, S.

10.1101/2019.12.19.882969 — developmental biology — Posted on 2019-12-20

905 Spectro-thermodynamics and molecular docking analysis of abiraterone and its binding to calf thymus DNA

Zargar, S.; Wani, T. A.; Bakheit, A. H.; Almehizia, A. A.; Khan, A. A.

10.1101/2019.12.19.883033 — cancer biology — Posted on 2019-12-20

906 Image Processing in DNA

Pan, C.; Tabatabaei Yazdi, S. M. H.; Tabatabaei, K.; Hernandez, A. G.; Schroeder, C.; Milenkovic, O.

10.1101/2019.12.15.877290 — bioinformatics — Posted on 2019-12-20

907 Interpretable Deep Temporal Structure Learning Model for Early Detection of Alzheimer's Disease

Wang, X.; Shen, D.; Huang, H.

10.1101/2019.12.12.874784 — neuroscience — Posted on 2019-12-20

908 Endocytosis frustration potentiates compression-induced receptor signaling

Baschieri, F.; Le Devedec, D.; Elkhatib, N.; Montagnac, G.

10.1101/2019.12.19.883066 — cell biology — Posted on 2019-12-20

909 Metabolic trade-offs expose unforeseen benefits of plasmids carriage

Reding Roman, R. C.

10.1101/810259 — evolutionary biology — Posted on 2019-12-20

910 Modulation of cortical slow oscillatory rhythm by GABAB receptors: an experimental and computational study

Perez-Zabalza, M.; Reig, R.; Manrique, J.; Jercog, D.; Winograd, M.; Parga, N.; Sanchez-Vives, M. V.

10.1101/2019.12.14.866442 — neuroscience — Posted on 2019-12-20

911 Integrin binding dynamics modulate ligand-specific mechanosensing in mammary gland fibroblasts

Lerche, M.; Elosegui-Artola, A.; Kechagia, J. Z.; Guzman, C.; Georgiadou, M.; Gulberg, D.; Roca-Cusachs, P.; Peuhu, E.; Ivaska, J.

10.1101/570721 — cell biology — Posted on 2019-12-20

912 Coverage-dependent bias creates the appearance of binary splicing in single cells

Buen Abad Najar, C. F.; Yosef, N.; Lareau, L. F.

10.1101/2019.12.19.883256 — genomics — Posted on 2019-12-20

913 Living materials with programmable functionalities grown from engineered microbial co-cultures

Gilbert, C.; Tang, T.-C.; Ott, W.; Dorr, B. A.; Shaw, W. M.; Sun, G. L.; Lu, T. K.; Ellis, T.

10.1101/2019.12.20.882472 — synthetic biology — Posted on 2019-12-20

914 Modeling of root nitrate responses suggests preferential foraging arises from the integration of demand, supply and local presence signals

Boer, M. D.; Santos Teixeira, J.; ten Tusscher, K. H.

10.1101/2019.12.19.882548 — plant biology — Posted on 2019-12-20

915 Modelling the role of LHCII-LHCII, PSII-LHCII and PSI-LHCII interactions in state transitions

Wood, W. H. J.; Johnson, M. P.

10.1101/2019.12.19.882886 — plant biology — Posted on 2019-12-20

916 Role of adenosine in functional recovery following anoxic coma in Locusta migratoria

Van Dusen, R. A.; Lanz, C.; Robertson, M.

10.1101/2019.12.19.882464 — physiology — Posted on 2019-12-20

917 Adding insult to injury: Effects of chronic oxybenzone exposure and elevated temperature on two reef-building corals

Wijgerde, T.; Ballegooijen, M. v.; Nijland, R.; Loos, L. v. d.; Kwadijk, C.; Osinga, R.; Murk, A.; Slijkerman, D.

10.1101/2019.12.19.882332 — pharmacology and toxicology — Posted on 2019-12-20

918 Quantitative and qualitative analysis of asynchronous neural activity

Ullner, E.; Politi, A.; Torcini, A.

10.1101/2019.12.19.882456 — neuroscience — Posted on 2019-12-20

919 Calcium channel-dependent induction of long-term synaptic plasticity at excitatory Golgi cell synapses of cerebellum

Locatelli, F.; Soda, T.; Montagna, I.; Tritto, S.; Botta, L.; Prestori, F.; D'Angelo, E.

10.1101/2019.12.19.882944 — neuroscience — Posted on 2019-12-20

920 X-ray 3D imaging of gene expression in whole-mount murine brain by microCT, implication for functional analysis of tRNA endonuclease 54 gene mutated in pontocerebellar hypoplasia.

Ermakova, O.; Orsini, T.; Fruscoloni, P.; Chiani, F.; Gambadoro, A.; Putti, S.; Cirilli, M.; Mezzi, A.; Kaciulis, S.; Raspa, M.; Ferdinando Scavizzi, F.; Tocchini-Valentini, G. P.

10.1101/2019.12.19.882688 — neuroscience — Posted on 2019-12-20

921 BOLD activation patterns and graph metrics associated with conscious tactile perception

Grund, M.; Forschack, N.; Nierhaus, T.; Villringer, A.

10.1101/2019.12.19.882365 — neuroscience — Posted on 2019-12-20

922 Hippocampus and amygdala fear memory engrams re-emerge after contextual fear reinstatement

Zaki, Y.; Mau, W.; Cincotta, C.; Vieira, A.; Doucette, E.; Grella, S. L.; Merfeld, E.; Murawski, N. J.; Shpokayte, M.; Ramirez, S.

10.1101/2019.12.19.882795 — neuroscience — Posted on 2019-12-20

923 A machine learning approach to define antimalarial drug action from heterogeneous cell-based screens

Ashdown, G. W.; Dimon, M.; Fan, M.; Teran, F. S.-R.; Witmer, K.; Gaboriau, D. C. A.; Armstrong, Z.; Hazard, J.; Ando, D. M.; Baum, J.

10.1101/2019.12.19.882480 — microbiology — Posted on 2019-12-20

924 Glioblastoma myeloid-derived suppressor cell subsets express differential macrophage migration inhibitory factor receptor profiles that can be targeted to reduce immune suppression

Alban, T.; Bayik, D.; Otvos, B.; Rabljenovic, A.; Leng, L.; Jia-shiun, L.; Roversi, G.; Lauko, A.; Momin, A.; Mohammadi, A. M.; Peereboom, D. M.; Ahluwalia, M. S.; Matsuda, K.; Yun, K.; Bucala, R.; Vogelbaum, M. A.; Lathia, J.

10.1101/2019.12.19.882555 — immunology — Posted on 2019-12-20

925 A Comparative Study of the Turnover of Multiciliated Cells in the Mouse Trachea, Oviduct and Brain

Roberson, E. C.; Tran, N. K.; Konjikusic, M. J.; Fitch, R. D.; GRAY, R.; Wallingford, J. B.

10.1101/2019.12.19.882878 — developmental biology — Posted on 2019-12-20

926 Identifying the causes and consequences of assembly gaps using a multiplatform genome assembly of a bird-of-paradise

Peona, V.; Blom, M. P. K.; Xu, L.; Burri, R.; Sullivan, S.; Bunikis, I.; Liachko, I.; Jonsson, K. A.; Zhou, Q.; Irestedt, M.; Suh, A.

10.1101/2019.12.19.882399 — genomics — Posted on 2019-12-20

927 Identification of genomic enhancers through spatial integration of single-cell transcriptomics and epigenomics

Bravo Gonzalez-Blas, C.; Quan, X.-J.; Duran-Romana, R.; Taskiran, I. I.; Koldere, D.; Davie, K.; Christiaens, V.; Makhzami, S.; Hulselmans, G.; de Waegeneer, M.; Mauduit, D.; Poovathingal, S.; Aibar, S.; Aerts, S.

10.1101/2019.12.19.882381 — genomics — Posted on 2019-12-20

928 HyPo: Super Fast & Accurate Polisher for Long Read Genome Assemblies

Kundu, R.; Casey, J.; Sung, W.-K.

10.1101/2019.12.19.882506 — bioinformatics — Posted on 2019-12-20

929 Druggability Assessment in TRAPP using Machine Learning Approaches

Yuan, J.-H.; Han, S. B.; Richter, S.; Wade, R. C.; Kokh, D. B.

10.1101/2019.12.19.882340 — bioinformatics — Posted on 2019-12-20

930 The association of DNA methylation with body mass index: distinguishing between predictors and biomarkers

Reed, Z. E.; Suderman, M. J.; Relton, C. L.; Davis, O. S. P.; Hemani, G.

10.1101/2019.12.16.877464 — genetics — Posted on 2019-12-20

931 Estimating the quality of eukaryotic genomes recovered from metagenomic analysis

Saary, P.; Mitchell, A. L.; Finn, R. D.

10.1101/2019.12.19.882753 — bioinformatics — Posted on 2019-12-20

932 Inter-domain dynamics in the chaperone SurA and multi-site binding to its unfolded outer membrane protein clients

Calabrese, A. N.; Schiffrin, B.; Watson, M. A.; Karamanos, T. K.; Walko, M.; Humes, J. R.; Horne, J. E.; White, P.; Wilson, A. J.; Kalli, A. C.; Tuma, R.; Ashcroft, A. E.; Brockwell, D. J.; Radford, S. E.

10.1101/2019.12.19.882696 — biochemistry — Posted on 2019-12-20

933 A dual mechanism underlying retroactive shifts of auditory spatial attention: dissociating target- and distractor-related modulations of alpha lateralization

Klatt, L.-I.; Getzmann, S.; Begau, A.; Schneider, D.

10.1101/2019.12.19.882324 — neuroscience — Posted on 2019-12-20

934 Enhanced sensory coding in mouse vibrissal and visual cortex through TRPA1

Kheradpezhouh, E.; Tang, M. F.; Mattingley, J. B.; Arabzadeh, E.

10.1101/2019.12.19.881896 — neuroscience — Posted on 2019-12-20

935 Cooling of medial septum reveals theta phase lag coordination of hippocampal cell assemblies

Petersen, P. C.; Buzsaki, G.

10.1101/2019.12.19.883421 — neuroscience — Posted on 2019-12-20

936 Tracking dynamic adjustments to decision making and performance monitoring processes in conflict tasks

Feuerriegel, D. C.; Jiwa, M.; Turner, W. F.; Andrejevic, M.; Hester, R.; Bode, S.

10.1101/2019.12.19.883447 — neuroscience — Posted on 2019-12-20

937 Correction of amyotrophic lateral sclerosis related phenotypes in induced pluripotent stem cell-derived motor neurons carrying a hexanucleotide expansion mutation in C9orf72 by CRISPR/Cas9 genome editing using homology-directed repair

Ababneh, N.; Scaber, J.; Flynn, R.; Douglas, A.; Turner, M. R.; Sims, D.; Dafinca, R.; Cowley, S. A.; Talbot, K.

10.1101/2019.12.17.864520 — neuroscience — Posted on 2019-12-20

938 Universal brain signature of emerging reading in two contrasting languages

Chyl, K.; Kossowski, B.; Wang, S.; Debska, A.; Łuniewska, M.; Marchewka, A.; Wypych, M.; van den Bunt, M.; Mencl, W.; Pugh, K.; Jednorog, K.

10.1101/2019.12.18.881672 — neuroscience — Posted on 2019-12-20

939 Moonlighting α-PheRS connects JAK/STAT with Notch signaling for intestinal homeostasis

Ho, M. T.; Lu, J.; Suter, B.

10.1101/2019.12.19.882530 — cell biology — Posted on 2019-12-20

940 A novel IKK- and proteasome-independent mechanism of RelA activation triggers senescence associated secretome via transcriptional repression of NFKBIA

Kolesnichenko, M.; Mikuda, N.; Höpken, U. E.; Milanovic, M.; Tufan, A. B.; Uyar, B.; Sun, W.; Schleich, K.; von Hoff, L.; Willenbrock, M.; Krahn, I.; Jungmann, S.; Hinz, M.; Akalin, A.; Lee, S.; Schmidt-Ullrich, R.; Schmitt, C. A.; Scheidereit, C.

10.1101/2019.12.19.882225 — cell biology — Posted on 2019-12-20

941 Social reprogramming in ants induces longevity-associated glia remodeling

Sheng, L.; Shields, E. J.; Gospocic, J.; Glastad, K. M.; Ratchasanmuang, P.; Raj, A.; Little, S.; Bonasio, R.

10.1101/2019.12.19.883181 — neuroscience — Posted on 2019-12-20

942 Becoming a better parent: mice learn sounds that improve a stereotyped maternal behavior

Dunlap, A. G.; Besosa, C.; Pascual, L. M.; Chong, K. K.; Walum, H.; Kacsoh, D. B.; Tankeu, B. B.; Lu, K.; Liu, R. C.

10.1101/2019.12.19.883041 — neuroscience — Posted on 2019-12-20

943 High Frequency Cortical Processing of Continuous Speech in Younger and Older Listeners

Kulasingham, J. P.; Brodbeck, C.; Presacco, A.; Kuchinsky, S. E.; Anderson, S.; Simon, J. Z.

10.1101/2019.12.19.883314 — neuroscience — Posted on 2019-12-20

944 Modulation of Yorkie activity by alternative splicing is required for developmental stability

Srivastava, D.; de Toledo, M.; Manchon, L.; Tazi, J.; Juge, F.

10.1101/2019.12.19.882779 — developmental biology — Posted on 2019-12-20

945 Mechanical model of muscle contraction. 4. Theoretical calculations of the tension during the isometric tetanus plateau and the tension exerted at the end of phase 1 of a length step

Louvet, S.

10.1101/2019.12.16.878843 — biophysics — Posted on 2019-12-19

946 Mechanical model of muscle contraction. 3. The orientation of the levers belonging to the myosin heads in working stroke follows the same uniform law in all half-sarcomeres of an isometrically stimulated fiber

Louvet, S.

10.1101/2019.12.16.878835 — biophysics — Posted on 2019-12-20

947 The R2TP chaperone assembles cellular machineries in intestinal CBC stem cells and progenitors

Maurizy, C.; Abeza, C.; Pinet, V.; Ferrand, M.; Paul, C.; Bremond, J.; Langa, F.; Gerbe, F.; Jay, P.; Verheggen, C.; Tinari, N.; Helmlinger, D.; Lattanzio, R.; Bertrand, E.; Hahne, M.; Pradet-Balade, B.

10.1101/2019.12.19.882712 — developmental biology — Posted on 2019-12-19

948 Optimising DNA-Coated Gold Nanoparticles to Enrich Skeletal Stem Cells from Human Bone Marrow Samples

Lanham, S.; Xavier, M.; Kyriazi, M.; Alexaki, K.; El-Sagheer, A.; Brown, T.; Kanaras, A.; Oreffo, R. O. C.

10.1101/2019.12.19.882563 — cell biology — Posted on 2019-12-19

949 The glue produced by Drosophila melanogaster for pupa adhesion is universal

Borne, F.; Kovalev, A.; Gorb, S.; Courtier-Orgogozo, V.

10.1101/2019.12.19.882761 — biophysics — Posted on 2019-12-19

950 Mechanical model of muscle contraction. 1. Force-velocity relationship

Louvet, S.

10.1101/2019.12.16.878793 — biophysics — Posted on 2019-12-19

951 Identifying age cohorts responsible for Peste des petits ruminants virus transmission among sheep, goats, and cattle in northern Tanzania

Herzog, C. M.; de Glanville, W. A.; Willett, B. J.; Cattadori, I. M.; Kapur, V.; Hudson, P. J.; Buza, J.; Swai, E. S.; Cleaveland, S.; Bjornstad, O. N.

10.1101/2019.12.19.882233 — ecology — Posted on 2019-12-19

952 14-3-3γ prevents centrosome duplication by inhibiting NPM1 function.

Bose, A.; Modi, K.; Dey, S.; Dalvi, S.; Nadkarni, P.; Sudarshan, M.; Kundu, T. K.; Venkatraman, P.; Dalal, S. N.

10.1101/2019.12.19.883264 — cell biology — Posted on 2019-12-19

953 Mechanical model of muscle contraction. 5. Tension rise after phase 1 of a length step

Louvet, S.

10.1101/2019.12.16.878868 — biophysics — Posted on 2019-12-19

954 Target membrane cholesterol modulates single influenza virus membrane fusion efficiency but not rate

Liu, K. N.; Boxer, S. G.

10.1101/2019.12.19.882738 — biophysics — Posted on 2019-12-19

955 smFRET Detects Dual Binding Modes Modulated by Proline Isomerization in a Mega-Dalton Multi-Enzyme Complex

Vera, A. M.; Galera-Prat, A.; Wojciechowski, M.; Rozycki, B.; Laurents, D. V.; Carrion-Vazquez, M.; Cieplak, M.; Tinnefeld, P.

10.1101/2019.12.19.882373 — biophysics — Posted on 2019-12-19

956 Mechanical model of muscle contraction. 6. Calculations of the tension exerted by a skeletal fiber during a shortening staircase

Louvet, S.

10.1101/2019.12.16.878876 — biophysics — Posted on 2019-12-19

957 Mechanical model of muscle contraction 2. Kinematic and dynamic aspects of a myosin II head during the working stroke

Louvet, S.

10.1101/2019.12.16.878801 — biophysics — Posted on 2019-12-19

958 Comparison of alternative models of human movement and the spread of disease

Bjornstad, O. N.; Grenfell, B.; Viboud, C.; King, A.

10.1101/2019.12.19.882175 — ecology — Posted on 2019-12-19

959 Prediction and Characterization of RXLR Effectors in Pythium Species

Ai, G.; Yang, K.; Tian, Y.; Ye, W.; Zhu, H.; Li, T.; Du, Y.; Xia, Q.; Shen, D.; Jing, M.; Xia, A.; Dou, D.

10.1101/2019.12.19.882209 — microbiology — Posted on 2019-12-19

960 Modeling the efficiency of filovirus entry into cells in vitro: Effects of SNP mutations in the receptor molecule

Kim, K. S.; Kondoh, T.; Asai, Y.; Takada, A.; Iwami, S.

10.1101/2019.12.19.882167 — microbiology — Posted on 2019-12-19

961 Close range vocal interaction in the common marmoset (Callithrix Jacchus)

Landman, R.; Sharma, J.; Hyman, J. B.; Fanucci-Kiss, A.; Meisner, O.; Parmar, S.; Feng, G.; Desimone, R.

10.1101/2019.12.19.882118 — animal behavior and cognition — Posted on 2019-12-19

962 Self-organization in brain tumors: how cell morphology and cell density influence glioma pattern formation

Jamous, S.; Comba, A.; Lowenstein, P. R.; Motsch, S.

10.1101/2019.12.19.882183 — systems biology — Posted on 2019-12-19

963 The effects of a 6-week core exercises on swimming performance of national level swimmers

Karpinski, J.; Rejdych, W.; Brzozowska, D.; Gołas, A.; Sadowski, W.; Swinarew, A. S.; Stachura, A.; Gupta, S.; Stanula, A.

10.1101/2019.12.19.882126 — scientific communication and education — Posted on 2019-12-19

964 Ser-653-Asn substitution in the acetohydroxyacid synthase gene confers resistance in weedy rice to imidazolinone herbicides imazapic and imazapyr in Malaysia

Ruzmi, R.; Ahmad Hamdani, M. S.; Mazlan, N.

10.1101/2019.12.19.882159 — plant biology — Posted on 2019-12-19

965 MYCORRHIZA CO-ASSOCIATION WITH Aspilia pruliseta Schweif AND PHOSPHORUS UPTAKE EFFECTS ON GROWTH ATTRIBUTES OF GADAM SORGHUM IN SELECTED SITES IN KENYA

MUCHOKA, J.; Njiru, D. M.; NTHAKANIO, P. N.; Mbugua, P. K.; Njeru, E. M.

10.1101/2019.12.19.882100 — microbiology — Posted on 2019-12-19

966 Intestinal parasites among rural schoolchildren in southern Ethiopia: A cross-sectional multilevel and zero-inflated regression model

Hailu, H.; Lindtjorn, B.; Bernt Lindtjorn,

10.1101/2019.12.19.882217 — microbiology — Posted on 2019-12-19

967 Genome mining of the citrus pathogen Elsinoë fawcettii; prediction and prioritisation of candidate effectors, cell wall degrading enzymes and secondary metabolite gene clusters

Jeffress, S.; Arun-Chinnappa, K.; Stodart, B.; Vaghefi, N.; Tan, Y. P.; Ash, G. J.

10.1101/2019.12.19.882142 — genomics — Posted on 2019-12-19

968 FluidFM as a Tool to Study Adhesion Forces of Bacteria - Optimization of Parameters and Comparison to Conventional Bacterial Probe Scanning Force Spectroscopy

Hofherr, L.; Müller-Renno, C.; Ziegler, C.

10.1101/2019.12.19.882134 — biophysics — Posted on 2019-12-19

969 Loss of function variants in PCYT1A causing spondylometaphyseal dysplasia with cone/rod dystrophy have broad consequences on lipid metabolism, chondrocyte differentiation, and lipid droplet formation.

Jurgens, J.; Chen, S.; Sobreira, N.; Robbins, S.; Franca Anzmann, A.; Dastgheyb, R.; Khuder, S. S.; Hoover-Fong, J.; Woods, C.; Collins, F.; Christodoulou, J.; Lopes Yamamoto, G.; Romeo Bertola, D.; Baratela, W. A. R.; Curie, S. D.; Haughey, N.; Cornell, R. B.; Valle, D.

10.1101/2019.12.19.882191 — genetics — Posted on 2019-12-19

970 Filamentation of the bacterial bi-functional alcohol/aldehyde dehydrogenase AdhE is essential for substrate channeling and enzymatic regulation.

Pony, P.; rapisarda, c.; terradot, l.; marza, e.; Fronzes, r.

10.1101/2019.12.19.882415 — microbiology — Posted on 2019-12-19

971 Microclimate buffering and thermal tolerance across elevations in a tropical butterfly

Montejo-Kovacevich, G.; Martin, S. H.; Meier, J. I.; Bacquet, C. N.; Monllor, M.; Jiggins, C. D.; Nadeau, N. J.

10.1101/2019.12.19.882357 — ecology — Posted on 2019-12-19

972 UMAP does not preserve global structure any better than t-SNE when using the same initialization

Kobak, D.; Linderman, G. C.

10.1101/2019.12.19.877522 — bioinformatics — Posted on 2019-12-19

973 Identification of a Novel Retrieval-Dependent Memory Process in the Crab Neohelice granulata

Merlo, S. A.; Santos, M. J.; Pedreira, M. E.; Merlo, E.

10.1101/2019.12.19.881128 — neuroscience — Posted on 2019-12-19

974 The vagus nerve mediates the suppressing effects of peripherally administered oxytocin on methamphetamine self-administration and seeking in rats

Everett, N. A.; Turner, A.; Costa, P.; Baracz, S. J.; Cornish, J.

10.1101/2019.12.18.880914 — neuroscience — Posted on 2019-12-19

975 Cell cycle dynamics of lamina associated DNA

van Schaik, T.; Vos, M.; Peric-Hupkes, D.; van Steensel, B.

10.1101/2019.12.19.881979 — molecular biology — Posted on 2019-12-19

976 ATM and PRDM9 Regulate SPO11-bound Recombination Intermediates During Meiosis

Paiano, J.; Wu, W.; Yamada, S.; Sciascia, N.; Callen, E.; Cotrim, A. P.; Deshpande, R.; Maman, Y.; Day, A.; Paull, T. T.; Nussenzweig, A.

10.1101/2019.12.18.881409 — molecular biology — Posted on 2019-12-19

977 Ca2+ ions promote fusion of Middle East Respiratory Syndrome coronavirus with host cells and increase infectivity

Straus, M. R.; Tang, T.; Lai, A. L.; Flegel, A.; Bidon, M.; Freed, J. H.; Daniel, S.; Whittaker, G. R.

10.1101/2019.12.18.881391 — microbiology — Posted on 2019-12-19

978 Fully Human Monoclonal Antibodies Effectively Neutralizing Botulinum Neurotoxin Serotype B

Matsumura, T.; Amatsu, S.; Misaki, R.; Yutani, M.; Du, A.; Kohda, T.; Fujiyama, K.; Ikuta, K.; Fujinaga, Y.

10.1101/2019.12.18.881920 — microbiology — Posted on 2019-12-19

979 Harnessing β-Lactam Antibiotics for Illumination of the Activity of Penicillin-Binding Proteins in Bacillus subtilis

Sharifzadeh, S.; Dempwolff, F.; Kearns, D. B.; Carlson, E. E.

10.1101/2019.12.19.881714 — microbiology — Posted on 2019-12-19

980 Thyroid and androgen receptor signaling are antagonized by CRYM in prostate cancer

Aksoy, O.; Pencik, J.; Hartenbach, M.; Moazzami, A. A.; Schlederer, M.; Balber, T.; Mazumder, B.; Whitchurch, J.; Roberts, C. J.; Susani, M.; Mitterhauser, M.; Marculescu, R.; Kramer, G.; Turner, S. D.; Hartenbach, S.; Tangermann, S.; Egger, G.; Neubauer, H. A.; Moriggl, R.; Culig, Z.; Hoermann, G.; Hacker, M.; Heery, D. M.; Merkel, O.; Kenner, L.

10.1101/2019.12.19.881151 — cancer biology — Posted on 2019-12-19

981 A portable, low-cost device for precise control of specimen temperature under stereomicroscopes

Testa, N. D.; Kaul, S.; Le, K. N.; Zhan, M.; Lu, H.; Paaby, A. B.

10.1101/2019.12.19.882605 — developmental biology — Posted on 2019-12-19

982 MR-Clust: Clustering of genetic variants in Mendelian randomization with similar causal estimates

Foley, C. N.; Kirk, P. D.; Burgess, S.

10.1101/2019.12.18.881326 — bioinformatics — Posted on 2019-12-19

983 The Human Telomeric Nucleosome Displays Distinct Structural and Dynamic Properties

Soman, A.; Liew, C. W.; Teo, H. L.; Berezhnoy, N. V.; Olieric, V.; Korolev, N.; Rhodes, D.; Nordenskioeld, L.

10.1101/2019.12.18.881755 — biochemistry — Posted on 2019-12-19

984 Implications of TP53 Allelic State for Genome Stability, Clinical Presentation and Outcomes in Myelodysplastic Syndromes

Bernard, E.; Nannya, Y.; Hasserjian, R. P.; Devlin, S. M.; Tuechler, H.; Medina-Martinez, J. S.; Yoshizato, T.; Shiozawa, Y.; Saiki, R.; Malcovati, L.; Levine, M. F.; Arango, J. E.; Zhou, Y.; Sole, F.; Cargo, C. A.; Haase, D.; Creignou, M.; Germing, U.; Zhang, Y.; Gundem, G.; Sarian, A.; van de Loosdrecht, A. A.; Jadersten, M.; Tobiasson, M.; Kosmider, O.; Follo, M. Y.; Thol, F.; Pinheiro, R. F.; Santini, V.; Kotsianidis, I.; Boultwood, J.; Santos, F. P. S.; Schanz, J.; Kasahara, S.; Ishikawa, T.; Tsurumi, H.; Takaori-Kondo, A.; Kiguchi, T.; Polprasert, C.; Bennett, J. M.; Klimek, V. M.; Savon

10.1101/2019.12.19.868844 — genomics — Posted on 2019-12-19

985 Correlation of p53 and DNA repair gene mutation patterns in human malignancies indicates different tumour suppression mechanisms of p53

Xue, X.; Dong, L.; Xue, L.; Lu, Y.-J.

10.1101/2019.12.19.877068 — cancer biology — Posted on 2019-12-19

986 Two tandem mechanisms control bimodal expression of the flagellar genes in Salmonella enterica

Wang, X.; Koirala, S.; Aldridge, P.; Rao, C.

10.1101/2019.12.18.881938 — microbiology — Posted on 2019-12-19

987 A clinically and genomically annotated nerve sheath tumor biospecimen repository.

Pollard, K.; Banerjee, J.; Doan, X.; Wang, J.; Guo, X.; Allaway, R. J.; Langmead, S.; Slobogean, B.; Meyer, C.; Loeb, D.; Morris, C.; Belzberg, A.; Blakeley, J. O.; Rodriguez, F.; Guinney, J.; Gosline, S. J.; Pratilas, C. A.

10.1101/2019.12.19.871897 — cancer biology — Posted on 2019-12-19

988 A neurocomputational model for intrinsic reward

Chew, B.; Blain, B.; Dolan, R. J.; Rutledge, R. B.

10.1101/2019.12.19.882589 — neuroscience — Posted on 2019-12-19

989 Thermal cycling protects SH-SY5Y cells against hydrogen peroxide and -amyloid-induced cell injury through stress response mechanisms involving Akt pathway

Chen, W.-T.; Kuo, Y.-Y.; Lin, G.-B.; Lu, C.-H.; Hsu, H.-P.; Sun, Y.-K.; Chao, C.-Y.

10.1101/2019.12.19.877373 — neuroscience — Posted on 2019-12-19

990 Ignoring correlated activity causes a failure of retinal population codes under moonlight conditions

Ruda, K.; Zylberberg, J.; Field, G. D.

10.1101/2019.12.18.881201 — neuroscience — Posted on 2019-12-19

991 Transient CRISPR immunity leads to coexistence with phages

Meaden, S.; Capria, L.; Alseth, E.; Biswas, A.; Lenzi, L.; Buckling, A.; van Houte, S.; Westra, E.

10.1101/2019.12.19.882027 — microbiology — Posted on 2019-12-19

992 Polygenic Risk for Skin Autoimmunity Impacts Immune Checkpoint Blockade in Bladder Cancer

Khan, Z.; Di Nucci, F.; Kwan, A.; Hammer, C.; Mariathasan, S.; Rouilly, V.; Carroll, J.; Fontes, M.; Ley Acosta, S.; Guardino, E.; Chen-Harris, H.; Bhangale, T.; Mellman, I.; Rosenberg, J.; Powles, T.; Hunkapiller, J.; Chandler, G. S.; Albert, M.

10.1101/2019.12.18.881805 — genetics — Posted on 2019-12-19

993 Relaxation times of ligand-receptor complex formation control T cell activation

Teimouri, H.; Kolomeisky, A. B.

10.1101/2019.12.18.881730 — biophysics — Posted on 2019-12-19

994 BioFabric Visualization of Network Alignments

Desai, R. M.; Longabaugh, W. J. R.; Hayes, W. B.

10.1101/2019.12.18.881664 — bioinformatics — Posted on 2019-12-19

995 Precision Sub-phenotyping of Histologically Stable Kidney Transplants by a Composite Molecular and Cellular Instability Score

Rychkov, D.; Sur, S.; Sirota, M.; Sarwal, M. M.

10.1101/2019.12.18.881706 — bioinformatics — Posted on 2019-12-19

996 Conserved function of ether lipids and sphingolipids in the early secretory pathway

Jimenez, N.; Leonetti, M.; Zoni, V.; Colom, A.; Feng, S.; Iyengar, N. R.; Matile, S.; Roux, A.; Vanni, S.; Weissman, J. S.; Riezman, H.

10.1101/2019.12.19.881094 — biochemistry — Posted on 2019-12-19

997 Investigating β-lactam drug targets in Mycobacterium tuberculosis using chemical probes

Beatty, K. E.; Levine, S. R.

10.1101/2019.12.19.881631 — biochemistry — Posted on 2019-12-19

998 Emergent biases in compensatory mutation can drive gene regulatory network evolution

Wang, Y.; Richards, M.; Dorus, S.; Priest, N. K.; Bryson, J. J.

10.1101/2019.12.18.881276 — systems biology — Posted on 2019-12-19

999 Flood-pulse disturbances as a threat for long-living Amazonian trees

Resende, A. F.; Piedade, M. T. F.; Feitosa, Y. O.; Andrade, V. H. F.; Trumbore, S. E.; Durgante, F. M.; Macedo, M. O.; Schongart, J.

10.1101/2019.12.18.872598 — ecology — Posted on 2019-12-19

1000 Making the best of a bad job? Chick mortality and flexible female brood care in Snowy Plovers

Kupan, K.; Szekely, T.; Cruz-Lopez, M.; Seymour, K.; Kuepper, C.

10.1101/2019.12.19.880856 — ecology — Posted on 2019-12-19

1001 Phase separation-mediated formation of condensed GIT/PIX enzyme complex module for compartmentalized signaling

Zhu, J.; Zhou, Q.; Xia, Y.; Lin, L.; Li, J.; Peng, M.; Zhang, R.; Zhang, M.

10.1101/2019.12.18.881771 — cell biology — Posted on 2019-12-19

1002 QuAdTrim: Overcoming computational bottlenecks insequence quality control

Robinson, A. J.; Ross, E. M.

10.1101/2019.12.18.870642 — bioinformatics — Posted on 2019-12-19

1003 Detection of aberrant splicing events in RNA-seq data with FRASER

Mertes, C.; Scheller, I.; Yepez, V. A.; Liang, Y.; Celik, M. H.; Kremer, L. S.; Gusic, M.; Prokisch, H.; Gagneur, J.

10.1101/2019.12.18.866830 — bioinformatics — Posted on 2019-12-19

1004 Robust Stability of Multicomponent Membranes: theRole of Glycolipids

Chen, Y.; Doelman, A.; Promislow, K.; Veerman, F.

10.1101/2019.12.19.882092 — biochemistry — Posted on 2019-12-19

1005 Widespread diversity in the transcriptomes of functionally divergent limb tendons

Disser, N. P.; Ghahramani, G. C.; Swanson, J. B.; Wada, S.; Chao, M. L.; Rodeo, S. A.; Oliver, D. J.; Mendias, C. L.

10.1101/2019.12.18.881797 — systems biology — Posted on 2019-12-19

1006 Theory of transcription bursting: Stochasticity in the transcription rates

Murugan, R.

10.1101/2019.12.18.880435 — systems biology — Posted on 2019-12-19

1007 Rapid method for generating designer algal mitochondrial genomes

Cochrane, R. R.; Brumwell, S. L.; Soltysiak, M. P. M.; Hamadache, S.; Davis, J. G.; Wang, J.; Tholl, S. Q.; Janakirama, P.; Edgell, D. R.; Karas, B. J.

10.1101/2019.12.19.882662 — synthetic biology — Posted on 2019-12-19

1008 Tuning Extracellular Electron Transfer by Shewanella oneidensis Using Transcriptional Logic Gates

Dundas, C. M.; Keitz, B. K.

10.1101/2019.12.18.881623 — synthetic biology — Posted on 2019-12-19

1009 Webina: An Open-Source Library and Web App that Runs AutoDock Vina Entirely in the Web Browser

Kochnev, Y.; Hellemann, E.; Cassidy, K. C.; Durrant, J. D.

10.1101/2019.12.18.881789 — pharmacology and toxicology — Posted on 2019-12-19

1010 Estimating Sparse Neuronal Signal from Hemodynamic Response: the Mixture Components Inference Approach

Pidnebesna, A.; Fajnerova, I.; Horacek, J.; Hlinka, J.

10.1101/2019.12.19.876508 — neuroscience — Posted on 2019-12-19

1011 Local sleep-like cortical reactivity in the awake brain after focal injury

Sarasso, S.; D'Ambrosio, S.; Fecchio, M.; Casarotto, S.; Vigano, A.; Landi, C.; Mattavelli, G.; Gosseries, O.; Quarenghi, M.; Laureys, S.; Devalle, G.; Rosanova, M.; Massimini, M.

10.1101/2019.12.19.882290 — neuroscience — Posted on 2019-12-19

1012 Visual experience instructs dendrite orientation but is not required for asymmetric wiring of the retinal direction selective circuit.

El-Quessny, M.; Maanum, K.; Feller, M. B.

10.1101/2019.12.19.873364 — neuroscience — Posted on 2019-12-19

1013 Integrase-RNA interactions underscore the critical role of integrase in HIV-1 virion morphogenesis

Elliott, J.; Eschbach, J. E.; Koneru, P. C.; Li, W.; Puray Chavez, M.; Townsend, D.; Lawson, D.; Engelman, A. N.; Kvaratskhelia, M.; Kutluay, S. B.

10.1101/2019.12.18.881649 — microbiology — Posted on 2019-12-19

1014 Revealing the impact of recurrent and rare structural variants in multiple myeloma

Rustad, E. H.; Yellapantula, V. D.; Glodzik, D.; Maclachlan, K. H.; Diamond, B.; Boyle, E. M.; Ashby, C.; Blaney, P.; Gundem, G.; Hultcrantz, M.; Leongamornlert, D.; Angelopoulos, N.; Auclair, D.; Zhang, Y.; Dogan, A.; Bolli, N.; Papaemmanuil, E.; Anderson, K. C.; Moreau, P.; Avet-Loiseau, H.; Munshi, N.; Keats, J.; Campbell, P.; Morgan, G. J.; Landgren, O.; Maura, F.

10.1101/2019.12.18.881086 — genomics — Posted on 2019-12-19

1015 Predicting genotypic values associated with gene interactions using neural networks: A simulation study for investigating factors affecting prediction accuracy

Onogi, A.

10.1101/2019.12.18.881912 — genetics — Posted on 2019-12-19

1016 Dancing bees evaluate agricultural forage resources as inferior to central urban land

Samuelson, A. E.; Schürch, R.; Leadbeater, E.

10.1101/2019.12.19.882076 — ecology — Posted on 2019-12-19

1017 MSL3 coordinates a transcriptional and translational meiotic program in female Drosophila

McCarthy, A.; Sarkar, K.; Martin, E. T.; Upadhyay, M.; James, J. R.; Lin, J. M.; Jang, S.; Williams, N. D.; Forni, P. E.; Buszczak, M.; Rangan, P.

10.1101/2019.12.18.879874 — developmental biology — Posted on 2019-12-19

1018 Loss of the Reissner Fiber and increased URP neuropeptide signaling underliescoliosis in a zebrafish ciliopathy mutant

VESQUE, C.; ANSELME, I.; PEZERON, G.; CANTAUT-BELARIF, Y.; ESCHSTRUTH, A.; DJEBAR, M.; LOPEZ-SANTOS, D.; LE RIBEUZ, H.; JENETT, A.; KHOURY, H.; VEZIERS, J.; PARMENTIER, C.; SCHNEIDER-MAUNOURY, S.

10.1101/2019.12.19.882258 — developmental biology — Posted on 2019-12-19

1019 PDX models reflect the proteome landscape of pediatric acute lymphoblastic leukemia but divert in select pathways

Uzozie, A. C.; Ergin, E. K.; Rolf, N.; Lorentzian, A.; Weng, S. S.; Nierves, L.; Smith, T. G.; Lim, C. J.; Maxwell, C. A.; Reid, G. S.; Lange, P. F.

10.1101/2019.12.18.880401 — cancer biology — Posted on 2019-12-19

1020 Finding a suitable library size to call variants in RNA-seq

Quaglieri, A.; Flensburg, C.; Speed, T. P.; Majewski, I. J.

10.1101/2019.12.18.881870 — bioinformatics — Posted on 2019-12-19

1021 Repeatability analysis improves the reliability of behavioral data

Rudeck, J.; Vogl, S.; Banneke, S.; Schoenfelder, G.; Lewejohann, L.

10.1101/2019.12.19.882043 — animal behavior and cognition — Posted on 2019-12-19

1022 TRA1: a locus responsible for controlling Agrobacterium-mediated transformability in barley.

Orman-Ligeza, B.; Harwood, W.; Hedley, P. E.; Hinchcliffe, A.; Macaulay, M.; Uauy, C.; Trafford, K.

10.1101/2019.12.19.882274 — plant biology — Posted on 2019-12-19

1023 ATN status in amnestic and non-amnestic Alzheimer's disease and frontotemporal lobar degeneration

Cousins, K. A.; Irwin, D. J.; Wolk, D. A.; Lee, E. B.; Shaw, L. M.; Trojanowski, J. Q.; Da Re, F.; Gibbons, G. S.; Grossman, M.; Phillips, J. S.

10.1101/2019.12.18.881441 — neuroscience — Posted on 2019-12-19

1024 Where can a place cell put its fields? Let us count the ways.

Yim, M. Y.; Sadun, L. A.; Fiete, I. R.; Taillefumier, T.

10.1101/2019.12.19.881458 — neuroscience — Posted on 2019-12-19

1025 A model of bidirectional interactions betweencomplementary learning systems for memoryconsolidation of sequential experiences

Howard, M. D.; Skorheim, S. W.; Pilly, P. K.

10.1101/2019.12.19.882035 — neuroscience — Posted on 2019-12-19

1026 Mismatch responses mediated by adaptation and deviance detection have complementary functional profiles that point to different auditory short-term memory systems

Teichert, T.; Jedema, H.; Shen, Z.; Gurnsey, K.

10.1101/2019.12.18.881821 — neuroscience — Posted on 2019-12-19

1027 mRNA with mammalian codon bias accumulates in yeast mutants with constitutive stress granules

Kozlova, N. V.; Pichon, C.; Rahmouni, A. R.

10.1101/2019.12.19.881961 — molecular biology — Posted on 2019-12-19

1028 Genomic analysis of carbapenemase-encoding plasmids from Klebsiella pneumoniae across Europe highlights three major patterns of dissemination

David, S.; Cohen, V.; Reuter, S.; Sheppard, A. E.; Giani, T.; Parkhill, J.; the European Survey of Carbapenemase-Producing Enterobacteriaceae (EuSCAPE) Working Group, ; the ESCMID Study Group for Epidemiological Markers (ESGEM), ; Rossolini, G. M.; Feil, E. J.; Grundmann, H.; Aanensen, D. M.

10.1101/2019.12.19.873935 — microbiology — Posted on 2019-12-19

1029 Collective cell migration and residual stress accumulation: modeling consideration

Pajic-Lijakovic, I.; Milivojevic, M.

10.1101/2019.12.18.881144 — developmental biology — Posted on 2019-12-19

1030 Enhanced canonical Wnt signaling during early zebrafish development perturbs the interaction of cardiac mesoderm and pharyngeal endoderm and causes thyroid specification defects

Vandernoot, I.; Haerlingen, B.; Trubiroha, A.; Gillotay, P.; Janssens, V.; Opitz, R.; Costagliola, S.

10.1101/2019.12.19.880815 — developmental biology — Posted on 2019-12-19

1031 Visualizing the metazoan proliferation-differentiation decision in vivo

Kohrman, A. Q.; Adikes, R. C.; Smith, J. J.; Martinez, M. A. Q.; Medwig-Kinney, T. N.; Palmisano, N. J.; Sallee, M. D.; Ahmed, O. B.; Weeks, N.; Kim, N.; Liu, S.; Zhang, W.; Pani, A. M.; Matus, D. Q.

10.1101/2019.12.18.881888 — developmental biology — Posted on 2019-12-19

1032 HIV-1 Env induces pexophagy and an oxidative stress leading to uninfected CD4+ T cell death

Daussy, C. F.; Galais, M.; Pradel, B.; Robert-Hebmann, V.; Sagnier, S.; Pattingre, S.; Biard-Piechaczyk, M.; Espert, L.

10.1101/2019.12.19.881110 — cell biology — Posted on 2019-12-19

1033 Wash and the WASH Regulatory Complex function in Nuclear Envelope budding

Verboon, J. M.; Nakamura, M.; Decker, J. R.; Davidson, K. A.; Nandakumar, V.; Parkhurst, S. M.

10.1101/2019.12.18.881763 — cell biology — Posted on 2019-12-19

1034 Robust detection of oncometabolic aberrations by 1H-13C heteronuclear single quantum correlation in live cells and intact tumors ex-vivo

Barekatain, Y.; Yan, V. C.; Arthur, K.; Ackroyd, J. J.; Khadka, S.; De Groot, J.; Huse, J. T.; Muller, F. L.

10.1101/2019.12.18.881177 — biophysics — Posted on 2019-12-19

1035 Water lily (Nymphaea thermarum) draft genome reveals variable genomic signatures of ancient vascular cambium losses

Povilus, R. A.; DaCosta, J. M.; Grassa, C.; Satyaki, P. R. V.; Moeglein, M.; Jaenisch, J.; Xi, Z.; Mathews, S.; Gehring, M.; Davis, C. C.; Friedman, W. E.

10.1101/2019.12.18.881573 — plant biology — Posted on 2019-12-19

1036 An in situ atlas of mitochondrial DNA in mammalian tissues reveals high content in stem/progenitor cells

Chen, J.; Zheng, Q.; Peiffer, L. B.; Hicks, J. L.; Haffner, M. C.; Rosenberg, A. Z.; Levi, M.; Wang, X. X.; Ozbek, B.; Yegnasubramanian, S.; De Marzo, A. M.

10.1101/2019.12.19.876144 — pathology — Posted on 2019-12-19

1037 Exaggerated Cortical Representation of Speech in Older Listeners: Mutual Information Analysis

Zan, P.; Presacco, A.; Anderson, S.; Simon, J. Z.

10.1101/2019.12.18.881334 — neuroscience — Posted on 2019-12-19

1038 Neural evidence of cognitive conflict during binocular rivalry

Drew, A.; Torralba, M.; Ruzzoli, M.; Fernandez, L. M.; Sabate, A.; Papai, M. S.; Faraco, S. S.

10.1101/2019.12.19.873141 — neuroscience — Posted on 2019-12-19

1039 Resolving the spatial profile of figure enhancement in human V1 through population receptive field modeling

Poltoratski, S.; Tong, F.

10.1101/2019.12.18.881722 — neuroscience — Posted on 2019-12-19

1040 Testing Hormone-specific Antibody Probes for Presumptive Detection and Separation of Contributor Cell Populations in Trace DNA Mixtures

Miller, J. A.; Brocato, E. R.; Yadavalli, V. K.; Greenspoon, S. A.; Ehrhardt, C. J.

10.1101/2019.12.18.881748 — molecular biology — Posted on 2019-12-19

1041 Highly parallelized microfluidic droplet cultivation and prioritization on antibiotic producers from complex natural microbial communities

Mahler, L.; Niehs, S.; Martin, K.; Weber, T.; Scherlach, K.; Agler-Rosenbaum, M.; Hertweck, C.; Roth, M.

10.1101/2019.12.18.877530 — microbiology — Posted on 2019-12-19

1042 Chromatin regulatory dynamics of early development and regional specification in a directed differentiation model of the human small intestine

Hung, Y.-H.; Huang, S.; Dame, M. K.; Spence, J. R.; Sethupathy, P.

10.1101/2019.12.18.881219 — genomics — Posted on 2019-12-19

1043 Methods for combining multiple correlated biomarkers with application to the study of low-grade inflammation and muscle mass in senior horses

Vsevolozhskaya, O.; Herbst, A.; Adams, A.; Burns, C.; Cantu, B.; Barker, V.; Zaykin, D.

10.1101/2019.12.18.881425 — genetics — Posted on 2019-12-19

1044 Towards an evolutionarily appropriate null model: jointly inferring demography and purifying selection

Johri, P.; Charlesworth, B.; Jensen, J. D.

10.1101/2019.12.18.881516 — evolutionary biology — Posted on 2019-12-19

1045 Prophylactic host behaviour discourages pathogen exploitation

Mitchell, E.; Wild, G.

10.1101/2019.12.18.881383 — evolutionary biology — Posted on 2019-12-19

1046 Analysis of model organism viability through an interspecies pathway comparison pipeline using the dynamic impact approach

Nguyen, A. D.; Bionaz, M.

10.1101/2019.12.18.448985 — bioinformatics — Posted on 2019-12-19

1047 Whisper 2: indel-sensitive short read mapping

Deorowicz, S.; Gudys, A.

10.1101/2019.12.18.881292 — bioinformatics — Posted on 2019-12-19

1048 A broad mutational target explains an evolutionary trend

Besnard, F.; Picao-Osorio, J.; Dubois, C.; Felix, M.-A.

10.1101/2019.12.18.881250 — evolutionary biology — Posted on 2019-12-19

1049 Periphilin self-association underpins epigenetic silencing by the HUSH complex

Prigozhin, D. M.; Albecka, A.; Douse, C. H.; Tchasovnikarova, I. A.; Timms, R. T.; Farleigh, L. E.; Oda, S.-i.; Freund, S. M.; Maslen, S.; Lehner, P. J.; Modis, Y.

10.1101/2019.12.18.881300 — biochemistry — Posted on 2019-12-19

1050 Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork

Baretic, D.; Jenkyn-Bedford, M.; Aria, V.; Cannone, G.; Skehel, M.; Yeeles, J. T. P.

10.1101/2019.12.18.880690 — biochemistry — Posted on 2019-12-19

1051 Dissection of demethylation and toxicity induced gene expression changes after decitabine treatment.

Turchinovich, A.; Surowy, H.; Tonevitsky, A.; Burwinkel, B.

10.1101/2019.12.18.880633 — molecular biology — Posted on 2019-12-19

1052 Productive bacterial communities exclude invaders

Jones, M. L.; Rivett, D. W.; Garcia, A. P.; Bell, T.

10.1101/2019.12.18.881102 — ecology — Posted on 2019-12-19

1053 Two distinct HIRA-dependent pathways handle H3.3 de novo deposition and recycling during transcription

Torne, J.; Ray-Gallet, D.; Boyarchuk, E.; Garnier, M.; Coulon, A.; Orsi, G. A.; Almouzni, G.

10.1101/2019.12.18.880716 — cell biology — Posted on 2019-12-19

1054 Vitamin D-binding protein is required for the maintenance of α-cell function and glucagon secretion

Viloria, K.; Nasteska, D.; Briant, L. J. B.; Helsing, S.; Larner, D.; Fine, N. H. F.; Ashford, F. B.; da Silva Xavier, G.; Jimenez Ramos, M.; Manning Fox, J. E.; MacDonald, P. E.; Akerman, I.; Lavery, G. G.; Flaxman, C.; Morgan, N. G.; Richardson, S. J.; Hewison, M.; Hodson, D. J.

10.1101/2019.12.19.881185 — physiology — Posted on 2019-12-19

1055 Physiological Adaptability and Parametric Versatility in a Simple Genetic Circuit

Chure, G.; Kaczmarek, Z. A.; Phillips, R.

10.1101/2019.12.19.878462 — biophysics — Posted on 2019-12-19

1056 Enhanced Cancer Subtyping via Pan-Transcriptomics Data Fusion, Monte-Carlo Consensus Clustering, and Auto Classifier Creation

Linton-Reid, K.; Thompson, J.; Clifford, H.

10.1101/2019.12.16.870188 — bioinformatics — Posted on 2019-12-19

1057 Background correlations selectively boost the gamma-sensitivity of cortical GABAergic neurons

Merino, R. M.; Leon-Pinzon, C.; Stuehmer, W.; Moeck, M.; Staiger, J. F.; Wolf, F.; Neef, A.

10.1101/2019.12.19.882639 — neuroscience — Posted on 2019-12-19

1058 An exhaustive analysis of single amino acid variants in helical transmembrane proteins

Llorian-Salvador, O.; Bernhofer, M.; Mahlich, Y.; Rost, B.

10.1101/2019.12.18.881318 — bioinformatics — Posted on 2019-12-19

1059 PUMA: PANDA Using MicroRNA Associations

Kuijjer, M. L.; Fagny, M.; Marin, A.; Quackenbush, J.; Glass, K.

10.1101/2019.12.18.874065 — systems biology — Posted on 2019-12-19

1060 LYS3 encodes a prolamin-box-binding transcription factor that controls embryo growth in barley and wheat

Trafford, K.; Orman-Ligeza, B.; Borrill, P.; Chia, T.; Chirico, M.; Dolezel, J.; Drea, S.; Karafiatov, M.; Schatlowski, N.; Solomon, C. U.; Steuernagel, B.; Wulff, B. B. H.; Uauy, C.

10.1101/2019.12.18.880955 — plant biology — Posted on 2019-12-19

1061 Acute stress enhances associative learning via dopamine signaling in the ventral lateral striatum

Stelly, C. E.; Tritley, S. C.; Rafati, Y.; Wanat, M. J.

10.1101/2019.12.18.881417 — neuroscience — Posted on 2019-12-19

1062 Estimating the prevalence of missing experiments in a neuroimaging meta-analysis

Samartsidis, P.; Montagna, S.; Laird, A. R.; Fox, P. T.; Johnson, T. D.; Nichols, T. E.

10.1101/225425 — neuroscience — Posted on 2019-12-19

1063 Odor Modulates the Temporal Dynamics of Fear Memory Consolidation

Grella, S. L.; Fortin, A.; McKissick, O.; Leblanc, H.; Ramirez, S.

10.1101/2019.12.19.881615 — neuroscience — Posted on 2019-12-19

1064 A role for the locus coeruleus in the modulation of feeding

Sciolino, N. R.; Mazzone, C. M.; Plummer, N. W.; Evsyukova, I.; Amin, J.; Smith, K. G.; McGee, C. A.; Fry, S. A.; Yang, C. X.; Powell, J. M.; Bruchas, M. R.; Kravitz, A. V.; Cushman, J. D.; Krashes, M. J.; Cui, G.; Jensen, P.

10.1101/2019.12.18.881599 — neuroscience — Posted on 2019-12-19

1065 Antidepressants act by binding to the transmembrane domain of TRKB receptor

Casarotto, P. C.; Girych, M.; Fred, S. M.; Moliner, R.; Enkavi, G.; Biojone, C.; Cannarozzo, C.; Brunello, C.; Winkel, F.; Steinzeig, A.; Patil, S.; Vestrig, S.; Serchov, T.; Kovaleva, V.; Diniz, C. R.; Laukkanen, L.; Cardon, I.; Antila, H.; Rog, T.; Saarma, M.; Bramham, C.; Normann, C.; Lauri, S.; Vattulainen, I.; Castren, E.

10.1101/757989 — neuroscience — Posted on 2019-12-19

1066 Differential Correlation of Serum BDNF and microRNA Content in Rats with Rapid or Late Onset of Heavy Alcohol Use

Ehinger, Y.; phamluong, K.; Darevesky, D.; Welman, M.; Moffat, J.; Sakhai, S.; Whiteley, E.; Berger, A.; Laguesse, S.; Farokhnia, M.; Leggio, L.; Lordkipanidze, M.; Ron, D.

10.1101/2019.12.18.881680 — neuroscience — Posted on 2019-12-19

1067 Lost and found: re-searching and re-scoring proteomics data aids the discovery of bacterial proteins and improves proteome coverage

Willems, P.; Fijalkowski, I.; Van Damme, P.

10.1101/2019.12.18.881375 — microbiology — Posted on 2019-12-19

1068 The rise of diversity in metabolic platforms across the Candidate Phyla Radiation

Jaffe, A. L.; Castelle, C. J.; Matheus Carnevali, P. B.; Gribaldo, S.; Banfield, J.

10.1101/2019.12.18.881540 — microbiology — Posted on 2019-12-19

1069 Mechanism underlying autoinducer recognition in the Vibrio cholerae DPO-VqmA quorum-sensing pathway

Huang, X.; Duddy, O. P.; Silpe, J. E.; Paczkowski, J. P.; Cong, J.; Henke, B. R.; Bassler, B. L.

10.1101/2019.12.19.881847 — microbiology — Posted on 2019-12-19

1070 Inclusion of Oxford Nanopore long reads improves all microbial and phage metagenome-assembled genomes from a complex aquifer system

Overholt, W. A.; Hölzer, M. A.; Geesink, P.; Diezel, C.; Marz, M.; Küsel, K.

10.1101/2019.12.18.880807 — microbiology — Posted on 2019-12-19

1071 Liquid-liquid microphase separation leads to formation of membraneless organelles

Ranganathan, S.; Shakhnovich, E.

10.1101/2019.12.18.881565 — biophysics — Posted on 2019-12-19

1072 Mucin hydrogel glyco-modulation to investigate immune activity of mucin glycans

Yan, H.; Hjorth, M.; Winkeljann, B.; Dobryden, I.; Lieleg, O.; Crouzier, T.

10.1101/2019.12.18.880757 — bioengineering — Posted on 2019-12-19

1073 Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases

Ritchie, S. C.; Liu, Y.; Lambert, S. A.; Teo, S. M.; Scepanovic, P.; Marten, J.; Zahid, S.; Chaffin, M.; Abraham, G.; Soranzo, N.; Burgess, S.; Drew, B. G.; Kathiresan, S.; Calkin, A.; Khera, A. V.; Danesh, J.; Butterworth, A. S.; Inouye, M.

10.1101/2019.12.14.876474 — genetics — Posted on 2019-12-19

1074 Tumor-targeted delivery of childhood vaccine recall antigens by attenuated Listeria reduces pancreatic cancer

Selvanesan, B. C.; Chandra, D.; Quispe-Tintaya, W.; Jahangir, A.; Patel, A.; Meena, K.; Alberto Alves Da Silva, R.; Li, J.; Siddiqui, S.; Libutti, S. K.; Yuan, Z.; Beck, A.; Tesfa, L.; Koba, W.; Chuy, J.; McAuliffe, J. C.; Jafari, R.; Entenberg, D.; Wang, Y.; Condeelis, J.; Gravekamp, C.

10.1101/600106 — immunology — Posted on 2019-12-19

1075 Persistent deleterious effects of an unstable deleterious Wolbachia infection

Ross, P. A.; Axford, J. K.; Callahan, A. G.; Richardson, K. M.; Hoffmann, A. A.

10.1101/853473 — evolutionary biology — Posted on 2019-12-19

1076 HIGD2A is required for assembly of the COX3 module of human mitochondrial complex IV

Hock, D. H.; Reljic, B.; Ang, C.-S.; Mountford, H. S.; Compton, A. G.; Ryan, M. T.; Thorburn, D. R.; Stroud, D. A.

10.1101/787721 — biochemistry — Posted on 2019-12-19

1077 A novel mycovirus evokes transcriptional rewiring in Malassezia and provokes host inflammation and an immunological response

Clancey, S. A.; Ruchti, F.; LeibundGut-Landmann, S.; Heitman, J.; Ianiri, G.

10.1101/2019.12.18.880518 — microbiology — Posted on 2019-12-19

1078 Interpretations of microbial community studies are biased by the selected 16S rRNA gene amplicon sequencing pipeline.

Straub, D.; Blackwell, N.; Langarica Fuentes, A.; Peltzer, A.; Nahnsen, S.; Kleindienst, S.

10.1101/2019.12.17.880468 — microbiology — Posted on 2019-12-19

1079 Cellular state determines the multimodal signaling response of single cells

Kramer, B. A.; Pelkmans, L.

10.1101/2019.12.18.880930 — systems biology — Posted on 2019-12-19

1080 Grant reviewer perceptions of the quality and effectiveness of panel discussion

Gallo, S. A.; Schmaling, K. B.; Thompson, L. A.; Glisson, S. R.

10.1101/586685 — scientific communication and education — Posted on 2019-12-19

1081 Efficient production of saffron crocins and picrocrocin in Nicotiana benthamiana using a virus-driven system

Marti, M.; Diretto, G.; Aragones, V.; Frusciante, S.; Ahrazem, O.; Gomez-Gomez, L.; Daros, J.-A.

10.1101/2019.12.18.880765 — plant biology — Posted on 2019-12-19

1082 Phylogenetic diversity and functional analysis of metal transporters of the Cation Diffusion Facilitator family from algae

Ibuot, A.; Dean, A. P.; Pittman, J. K.

10.1101/2019.12.18.880724 — plant biology — Posted on 2019-12-19

1083 When does diet matter? The roles of larval and adult nutrition in regulating adult size traits.

Pocas, G. M.; Crosbie, A.; Mirth, C. K.

10.1101/2019.12.18.880708 — physiology — Posted on 2019-12-19

1084 Acid sensing ion channel 1a is a key mediator of cardiac ischemia-reperfusion injury

Redd, M.; Scheuer, S.; Saez, N.; Gao, L.; Hicks, M.; Villanueva, J.; Reichelt, M.; Peart, J.; See Hoe, L.; Chiu, H.; Chen, X.; Sun, Y.; Suen, J.; Hatch, R.; Rollo, B.; Alzubaidi, M.; Maljevic, S.; Qaiffe-Ryan, G. A.; Thomas, W.; Hudson, J. E.; Porrello, E.; Cuellar-Partida, G.; Fraser, J.; Petrou, S.; King, G.; MacDonald, P.; Palpant, N.

10.1101/869826 — physiology — Posted on 2019-12-19

1085 Frequency- and state-dependent effects of hippocampal neural disinhibition on hippocampal local field potential oscillations in anaesthetised rats

Gwilt, M.; Bauer, M.; Bast, T.

10.1101/2019.12.18.880864 — neuroscience — Posted on 2019-12-19

1086 Push-pull regulation of exploratory behavior by two opposing hippocampal to prefrontal cortex pathways

Sanchez Bellot, C.; MacAskill, A. F.

10.1101/2019.12.18.880831 — neuroscience — Posted on 2019-12-19

1087 AMPAR/TARP stoichiometry differentially modulates channel properties

Miguez-Cabello, F.; Sanchez-Fernandez, N.; Yefimenko Nosova, N.; Gasull Casanova, X.; Gratacos-Batlle, E.; Soto, D.

10.1101/2019.12.16.877506 — neuroscience — Posted on 2019-12-19

1088 Spatial suppression in visual motion perception is driven by inhibition: evidence from MEG gamma oscillations

Orekhova, E. V.; Ekaterina, R. N.; Viktoria, M. O.; Prokofyev, A.; Obukhova, T. S.; Nikolaeva, A. Y.; Schneiderman, J. F.; Stroganova, T. A.

10.1101/861765 — neuroscience — Posted on 2019-12-19

1089 Multiple testing correction over contrasts for brain imaging

Visineski Alberton, B. A.; Nichols, T. E.; Gamba, H. R.; Winkler, A. M.

10.1101/775106 — neuroscience — Posted on 2019-12-19

1090 Cell-specific exon methylation and CTCF binding in neurons regulates calcium ion channel splicing and function

Lopez Soto, E. J.; Lipscombe, D.

10.1101/2019.12.15.876185 — neuroscience — Posted on 2019-12-19

1091 Two separate roles for the transcription coactivator SAGA and a set of genes redundantly regulated by TFIID and SAGA

Donczew, R.; Warfield, L.; Pacheco, D.; Erijman, A.; Hahn, S.

10.1101/745059 — molecular biology — Posted on 2019-12-19

1092 Transcriptome analysis of Tartary Buckwheat reveals the differential expression of salt pathway genes

Song, J.-N.; Liu, X.-H.; Wang, Y.-Q.; Yang, H.-B.

10.1101/869263 — genomics — Posted on 2019-12-19

1093 Inventive nesting behaviour in the keyhole wasp Pachodynerus nasidens Latreille (Hymenoptera: Vespidae) in Australia, and the risk to aviation safety

House, A. P. N.; Ring, J. G.; Shaw, P. P.

10.1101/2019.12.15.877274 — ecology — Posted on 2019-12-19

1094 Neuropeptide F receptor acts in the Drosophila prothoracic gland to regulate growth and developmental timing

Kannangara, J. R.; Henstridge, M. A.; Parsons, L. M.; Kondo, S.; Mirth, C. K.; Warr, C. G.

10.1101/2019.12.16.878967 — developmental biology — Posted on 2019-12-19

1095 Use of dual electron probes reveals role of ferritin in erythropoiesis

Aronova, M. A.; Noh, S. J.; Zhang, G.; Byrnes, C.; Meier, E. R.; Kim, Y. C.; Leapman, R. D.

10.1101/866889 — cell biology — Posted on 2019-12-19

1096 AMR - An R Package for Working with Antimicrobial Resistance Data

Berends, M. S.; Luz, C. F.; Friedrich, A. W.; Sinha, B. N.; Albers, C. J.; Glasner, C.

10.1101/810622 — microbiology — Posted on 2019-12-19

1097 Growth rate alterations of human colorectal cancer cells by 157 gut bacteria

Taddese, R.; Garza, D. R.; Ruiter, L. N.; de Jonge, M. I.; Belzer, C.; Aalvink, S.; Nagtegaal, I. D.; Dutilh, B. E.; Boleij, A.

10.1101/2019.12.14.876367 — microbiology — Posted on 2019-12-19

1098 Reward modulates behaviour and neural responses in motor cortex during action observation

Cretu, A. L.; Lehner, R.; Polania, R.; Wenderoth, N.

10.1101/868083 — neuroscience — Posted on 2019-12-19

1099 Admixture/fine-mapping in Brazilians reveals a West African associated potential regulatory variant (rs114066381) with a strong female-specific effect on body mass- and fat mass-indexes

Scliar, M. O.; Sant Anna, H. P.; Santolalla, M. L.; Leal, T. P.; Araujo, N. M.; Alvim, I.; Borda, V.; Magalhaes, W. C.; Gouveia, M. H.; Lyra, R.; Machado, M.; Michelin, L.; Rodrigues, M. R.; Araujo, G. S.; Kehdy, F. S.; Zolini, C.; Peixoto, S. V.; Luizon, M.; Lobo, F. P.; Naslavsky, M. S.; Yamamoto, G. L.; Duarte, Y. A.; Hansen, M. E.; Norris, S. A.; Gilman, R. H.; Guio, H.; Hsing, A.; Mbulaiteye, S. M.; Mensah, J.; Dutil, J.; Yeager, M.; Yeboah, E.; Tishkoff, S. A.; Choudhury, A.; Ramsay, M.; Passos-Bueno, M. R.; Zatz, M.; O'Connor, T. D.; Pereira, A. C.; Barreto, M. L.; Lima-Costa, M. F.; Ho

10.1101/827311 — genetics — Posted on 2019-12-19

1100 Transcription-independent TFIIIC-bound sites cluster near heterochromatin boundaries within lamina-associated domains in C. elegans

Stutzman, A. V.; Liang, A.; Beilinson, V.; Ikegami, K.

10.1101/813642 — molecular biology — Posted on 2019-12-19

1101 Nanopore-based native RNA sequencing provides insights into prokaryotic transcription, operon structures, rRNA maturation and modifications

Grünberger, F.; Knüppel, R.; Jüttner, M.; Fenk, M.; Borst, A.; Reichelt, R.; Soppa, J.; Ferreira-Cerca, S.; Grohmann, D.

10.1101/2019.12.18.880849 — microbiology — Posted on 2019-12-19

1102 Complementary inhibitory weight profiles emerge from plasticity and allow attentional switching of receptive fields

Agnes, E. J.; Luppi, A. I.; Vogels, T. P.

10.1101/729988 — neuroscience — Posted on 2019-12-19

1103 A novel thermal-visual place learning paradigm for honeybees

Scheiner, R.; Frantzmann, F.; Jaeger, M.; Helfrich-Foerster, C.; Pauls, D.

10.1101/2019.12.18.880898 — neuroscience — Posted on 2019-12-19

1104 Sox8 and Sox9 act redundantly for ovarian-to-testicular fate reprogramming in the absence of Rspo1 in mouse sex reversal

Richardson, N.; Gillot, I.; Gregoire, E. P.; Youssef, S. A.; de Rooij, D.; de Bruin, A.; De Cian, M.-C.; Chaboissier, M.-C.

10.1101/2019.12.13.875443 — developmental biology — Posted on 2019-12-19

1105 Mechano-calcium and mechano-electric feedbacks in the human cardiomyocyte analyzed in a mathematical model

Balakina-Vikulova, N. A.; Panfilov, A.; Solovyova, O.; Katsnelson, L. B.

10.1101/855890 — biophysics — Posted on 2019-12-19

1106 A novel resistance pathway for calcineurin inhibitors in the human pathogenic Mucorales Mucor circinelloides

Vellanki, S.; Billmyre, R. B.; Lorenzen, A.; Campbell, M.; Turner, B.; Huh, E. Y.; Heitman, J.; Lee, S. C.

10.1101/834143 — microbiology — Posted on 2019-12-19

1107 ReferenceSeeker: rapid determination of appropriate reference genomes

Schwengers, O.; Hain, T.; Chakraborty, T.; Goesmann, A.

10.1101/863621 — bioinformatics — Posted on 2019-12-19

1108 Maximizing prediction of orphan genes in assembled genomes

Seetharam, A. S.; Singh, U.; Li, J.; Bhandary, P.; Arendsee, Z.; Wurtele, E. S.

10.1101/2019.12.17.880294 — bioinformatics — Posted on 2019-12-19

1109 Confronting p-hacking: addressing p-value dependence on sample size

Gomez-de-Mariscal, E.; Sneider, A.; Jayatilaka, H.; Phillip, J. M.; Wirtz, D.; Munoz-Barrutia, A.

10.1101/2019.12.17.878405 — bioinformatics — Posted on 2019-12-19

1110 Disrupting Transcriptional Feedback Yields an Escape-Resistant Antiviral

Chaturvedi, S.; Wolf, M.; Glazier, J.; Vardi, N.; Chan, M.; Weinberger, L.

10.1101/464495 — microbiology — Posted on 2019-12-19

1111 The lipid kinase PI3Kα is required for aggregation and survival of intraperitoneal cancer cells.

Thole, A.; Thibault, B.; Basset, C.; Guillermet-Guibert, J.

10.1101/777649 — cancer biology — Posted on 2019-12-19

1112 Conjunctive changes in two distinct ion channels mediate activity-dependent intrinsic plasticity in rat dentate gyrus granule cells

Mishra, P.; Narayanan, R.

10.1101/747550 — neuroscience — Posted on 2019-12-19

1113 Ubiquitin Links Smoothened to Intraflagellar Transport to Regulate Hedgehog Signaling

Desai, P. B.; Stuck, M. W.; Lv, B.; Pazour, G. J.

10.1101/2019.12.18.880799 — cell biology — Posted on 2019-12-19

1114 Identification of Six novel missense single nucleotide polymorphisms in MAOA gene predisposing to aggressive behavior. Bioinformatics study.

Abdelmoneim, A. H.; Mustafa, M. I.; Murshed, N. S.; Omer, N. S.; Mohammed, A. I.; Makhawi, A. M.

10.1101/2019.12.18.880963 — bioinformatics — Posted on 2019-12-19

1115 SHAMAN: a user-friendly website for metataxonomic analysis from raw reads to statistical analysis

Volant, S.; Lechat, P.; Woringer, P.; Motreff, L.; Malabat, C.; Kennedy, S.; Ghozlane, A.

10.1101/2019.12.18.880773 — bioinformatics — Posted on 2019-12-19

1116 Dopamine modulates paranoid social inferences: a double-blind, within-subject, randomised control study in a healthy population.

Barnby, J. M.; Bell, V.; Deeley, Q.; Mehta, M. A.

10.1101/2019.12.18.874255 — neuroscience — Posted on 2019-12-19

1117 CDE-1 suppresses the production of risiRNA by coupling polyuridylation and degradation of 26S rRNA

Wang, Y.; Weng, C.; Chen, X.; Zhou, X.; Huang, X.; Dong, M.; Yan, Y.; Zhu, C.; Guang, S.

10.1101/2019.12.18.880609 — molecular biology — Posted on 2019-12-19

1118 Using force data to self-pace an instrumented treadmill and measure self-selected walking speed

Song, S.; Choi, H.; Collins, S. H.

10.1101/2019.12.18.870592 — bioengineering — Posted on 2019-12-19

1119 Murine models of renal ischaemia reperfusion injury: An opportunity for refinement using non-invasive monitoring methods

Harwood, R.; Bridge, J.; Ressel, L.; Scarfe, L.; Sharkey, J. W.; Czanner, G.; Garcia-Finana, M.; Kalra, P.; Odudu, A.; Kenny, S.; Wilm, B.; Murray, P.

10.1101/2019.12.17.879742 — physiology — Posted on 2019-12-19

1120 Closed-loop Neuroscience of brain rhythms: optimizing real-time quantification of narrow-band signals to expedite feedback delivery

Smetanin, N.; Belinskaya, A.; Lebedev, M.; Ossadtchi, A.

10.1101/2019.12.18.880450 — neuroscience — Posted on 2019-12-19

1121 A Model for Navigation in Unknown Environments Based on a Reservoir of Hippocampal Sequences

Leibold, C.

10.1101/2019.12.18.880583 — neuroscience — Posted on 2019-12-19

1122 Offline tDCS modulates prefrontal cortical-subcortical cerebellar fear pathways in delayed fear extinction

Avila, A. G.; Guiomar, R.; Valerio, D.; Goncalves, O. F.; Almeida, J.

10.1101/2019.12.18.880658 — neuroscience — Posted on 2019-12-19

1123 Complete genome sequence and comparative genomics of the fish pathogen Streptococcus iniae QMA0248

Alsheikh-Hussain, A. S.; Ben Zakour, N. L.; Forde, B. M.; Silayeva, O.; Barnes, A. C.; Beatson, S. A.

10.1101/2019.12.17.880476 — microbiology — Posted on 2019-12-19

1124 A novel totivirus alters gene expression and vacuolar morphology in Malassezia cells and induces a TLR3-mediated inflammatory immune response

Park, M.; Cho, Y.-J.; Kim, D.; Yang, C.-S.; Lee, S. M.; Dawson, T.; Nakamizo, S.; Kabashima, K.; Lee, Y. W.; Jung, W. H.

10.1101/2019.12.17.880526 — microbiology — Posted on 2019-12-19

1125 Deformed Wing Virus spillover from honey bees to bumble bees: a reverse genetic study.

Gusachenko, O. N.; Woodford, L.; Balbirnie-Cumming, K.; Ryabov, E. V.; Evans, D. J.

10.1101/2019.12.18.880559 — microbiology — Posted on 2019-12-19

1126 A MUC5B polymorphism associated with Idiopathic Pulmonary Fibrosis mediates overexpression through decreased CpG methylation and C/EBPb transcriptional activation

Armesto-Jimenez, A. U.; Arason, A. J.; Stefasson, O. A.; Gudmundsson, G.; Gudjonsson, T.; Magnusson, M. K.

10.1101/2019.12.18.880674 — genetics — Posted on 2019-12-19

1127 Increased juvenile survival may not be universally linked to longevity: ecological, social and life-history drivers of age-specific mortality in birds

Mourocq, E.; Griesser, M.; Drobniak, S. M.

10.1101/2019.12.18.880682 — evolutionary biology — Posted on 2019-12-19

1128 Developing a DeSipher method for conformational change detection of membrane receptor complex at residue resolution

Liu, Q.; He, Q.-t.; Lyu, X.-x.; Yang, F.; Zhu, Z.-l.; Xiao, P.; Yang, Z.; Zhang, F.; Yang, Z.-y.; Wang, X.-y.; Sun, P.; Wang, Q.-w.; Qu, C.-x.; Gong, Z.; Lin, J.-Y.; Xu, Z.; Song, S.-l.; Huang, S.-m.; Guo, S.-c.; Han, M.-j.; Zhu, K.-k.; Chen, X.; Kahsai, A. W.; Xiao, K.-H.; Kong, W.; Yu, X.; Ruan, K.; Li, F.-h.; Niu, X.-g.; Jin, C.-w.; Wang, J.; Sun, J.

10.1101/2019.12.18.873729 — biochemistry — Posted on 2019-12-19

1129 UHRF1-SRA recognizes symmetric non-CG methylated DNA through dual-flip out of 5-methyl cytosines

Nakarakanti, N. K.; Abhishek, S.; Deeksha, W.; Eerappa, R.

10.1101/2019.12.17.880419 — biophysics — Posted on 2019-12-19

1130 Computer-aided Binding Mode Prediction and Affinity Maturation of LRR Protein Binder without Structural Determination

Choi, Y.; Jeong, S.; Choi, J.-M.; Ndong, C.; Bailey-Kellogg, C.; Griswold, K. E.; Kim, H.-S.

10.1101/2019.12.18.880534 — bioinformatics — Posted on 2019-12-19

1131 FACS: antimicrobial peptide screening in genomes and metagenomes

Santos-Junior, C. D.; Pan, S.; Zhao, X.-M.; Coelho, L. P.

10.1101/2019.12.17.880385 — bioinformatics — Posted on 2019-12-19

1132 Gene regulatory architectures dissect the evolutionary dynamics of regulatory elements in humans and non-human primates

Garcia-Perez, R.; Esteller-Cucala, P.; Mas, G.; Lobon, I.; Di Carlo, V.; Kuhlwilm, M.; Riera, M.; Navarro, A.; Blancher, A.; Di Croce, L.; Gomez-Skarmeta, J. L.; Juan, D.; Marques-Bonet, T.

10.1101/2019.12.18.872531 — evolutionary biology — Posted on 2019-12-19

1133 Imputed Genomic Data Reveals a Moderate Effect of Low Frequency Variants to the Heritability of Complex Human Traits

Hartman, K. A.; Rashkin, S. R.; Witte, J. S.; Hernandez, R. D.

10.1101/2019.12.18.879916 — genomics — Posted on 2019-12-19

1134 Peripheral tolerance to insulin is encoded by mimicry in the microbiome

Rubio Garcia, A.; Paterou, A.; Lee, M.; Slawinski, H.; Wicker, L. S.; Todd, J. A.; Pekalski, M. L.

10.1101/2019.12.18.881433 — immunology — Posted on 2019-12-19

1135 Extensive Mammalian Germline Genome Engineering

Yang, L.; Gao, Y.; Yue, Y.; Kan, Y.; Xu, W.; Church, G. M.; Qin, W.; Zhao, H.-Y.; Zhou, Y.; Song, X.; Wei, H.-J.; Goswami, D.; Yang, M.; Lamriben, L.; Wu, J.; Xiong, J.; Xu, M.; Zhang, Q.; Yu, L.; Guo, J.; Mao, S.; Jiao, D.; Nguyen, T. D.; Li, Z.; Layer, J. V.; Li, M.; Paragas, V.; Youd, M. E.; Sun, Z.; Ding, Y.; Wang, W.; Dou, H.; Song, L.; Le, L.; Fang, X.; George, H.; Anand, R.; Wang, S. Y.; Markmann, J.; Guell, M.; Westlin, W. F.

10.1101/2019.12.17.876862 — synthetic biology — Posted on 2019-12-19

1136 Structural brain architectures match intrinsic functional networks and vary across domains: A study from 15000+ individuals

Luo, N.; SUI, J.; Abrol, A.; Turner, J. A.; Damaraju, E.; Fu, Z.; Fan, L.; Chen, J.; Lin, D.; Zhuo, C.; Xu, Y.; Glahn, D. C.; Rodrigue, A. L.; Banich, M. T.; Pearlson, G. D.; Calhoun, V. D.

10.1101/2019.12.17.879502 — neuroscience — Posted on 2019-12-19

1137 Semilunar Granule Cells Maintain Distinct Dendritic Morphology and Inhibition through Postnatal Development and Receive Heightened Inhibition in Adolescence

Gupta, A.; Subramanian, D.; Proddutur, A.; Chang, Y.-J.; Guevarra, J.; Shah, Y.; Elgammal, F. S.; Santhakumar, V.

10.1101/2019.12.17.880005 — neuroscience — Posted on 2019-12-19

1138 Dual Orexin and MCH neuron-ablated mice display severe sleep attacks and cataplexy

Yamanaka, A.; Hung, C. J.; Ono, D.; Kilduff, T. S.

10.1101/2019.12.17.880229 — neuroscience — Posted on 2019-12-19

1139 Xi rhythms: decoding neural oscillations to create full brain high resolution spectra parametric mapping

Hu, S.; Valdes-Sosa, P. A.

10.1101/2019.12.17.880328 — neuroscience — Posted on 2019-12-19

1140 A sulfoglycolytic Entner-Doudoroff pathway in Rhizobium leguminosarum bv. trifolii SRDI565

Li, J.; Epa, R.; Lingford, J. P.; Scott, N.; Skoneczny, D.; Sharma, M.; Snow, A.; Goddard-Borger, E. D.; Davies, G. J.; McConville, M. J.; Williams, S. J.

10.1101/2019.12.17.868638 — microbiology — Posted on 2019-12-19

1141 Molecular basis of differential parasitism between non-encapsulated and encapsulated Trichinella revealed by a high-quality genome assembly

Liu, X.; Feng, Y.; Bai, X.; Wang, X.; Qin, R.; Tang, B.; Yu, X.; Yang, Y.; Liu, M.; Gao, F.

10.1101/2019.12.17.880336 — genomics — Posted on 2019-12-19

1142 Different strategies to manage Varroa jacobsoni and Tropilaelaps mercedesae in Papua New Guinea

Roberts, J.; Schouten, C. N.; Sengere, R.; Jave, J.; Lloyd, D.

10.1101/2019.12.17.880393 — ecology — Posted on 2019-12-19

1143 Bio-DIA: A web-based tool for data and algorithms integration

Dantas Soares, T.; Lira da Silva, V.; Luis Fonseca Faustino, A.; de Azevedo Morais, D. A.; Signoretti, A.; Figuerola, W. B.

10.1101/2019.12.13.875666 — bioinformatics — Posted on 2019-12-19

1144 Foraging behavior across paths that vary in risk cues and frequency of occurrence

Lessig, E. K.; Nonacs, P.

10.1101/2019.12.17.878819 — animal behavior and cognition — Posted on 2019-12-19

1145 Design of DNA Origami Diamond Photonic Crystals

Park, S. H.; Park, H.; Hur, K.; Lee, S.

10.1101/2019.12.17.880302 — synthetic biology — Posted on 2019-12-19

1146 Culex saltanensis and Culex interfor (Diptera: Culicidae) are susceptible and competent to transmit St. Louis encephalitis virus (Flavivirus: Flaviviridae) in central Argentina.

Beranek, M.; Quaglia, A.; Peralta, G.; Flores, F.; Stein, M.; Diaz, A.; Almiron, W.; Contigiani, M.

10.1101/722579 — microbiology — Posted on 2019-12-19

1147 Case-control design identifies ecological drivers of endemic coral diseases

Caldwell, J. M.; Aeby, G.; Heron, S. F.; Donahue, M. J.

10.1101/662320 — ecology — Posted on 2019-12-19

1148 BiSCoT: Improving large eukaryotic genome assemblies with optical maps

Istace, B.; Belser, C.; Aury, J.-M.

10.1101/674721 — bioinformatics — Posted on 2019-12-19

1149 Completing Linneaus's inventory of the Swedish insect fauna: only 5,000 species left?

Ronquist, F.; Forshage, M.; Häggqvist, S.; Karlsson, D.; Hovmöller, R.; Bergsten, J.; Holston, K.; Britton, T.; Abenius, J.; Andersson, B.; Buhl, P. N.; Coulianos, C.-C.; Fjellberg, A.; Gertsson, C.-A.; Hellqvist, S.; Jaschhof, M.; Kjaerandsen, J.; Klopfstein, S.; Kobro, S.; Liston, A.; Meier, R.; Pollet, M.; Riedel, M.; Rohacek, J.; Schuppenhauer, M.; Stigenberg, J.; Struwe, I.; Taeger, A.; Ulefors, S.-O.; Varga, O.; Withers, P.; Gärdenfors, U.

10.1101/687392 — ecology — Posted on 2019-12-19

1150 SequelTools: A Suite of Tools for Working with PacBio Sequel Raw Sequence Data

Hufnagel, D. E.; Hufford, M. B.; Seetharam, A. S.

10.1101/611814 — bioinformatics — Posted on 2019-12-19

1151 DiADeM: differential analysis via dependency modelling of chromatin interactions with robust generalized linear models

Zaborowski, R.; Wilczynski, B.

10.1101/654699 — bioinformatics — Posted on 2019-12-19

1152 Dissociable Neural Correlates of Uncertainty Underlie Different Exploration Strategies

Tomov, M.; Truong, V.; Hundia, R.; Gershman, S.

10.1101/478131 — neuroscience — Posted on 2019-12-19

1153 Tracing foot-and-mouth disease virus phylogeographical patterns and transmission dynamics

Jara, M.; Frias-De-Diego, A.; Dellicour, S.; Baele, G.; Machado, G.

10.1101/590612 — epidemiology — Posted on 2019-12-19

1154 A tool for browsing the Cancer Dependency Map reveals functional connections between genes and helps predict the efficacy and selectivity of candidate cancer drugs

Shimada, K.; Muchlich, J. L.; Mitchison, T. J.

10.1101/2019.12.13.874776 — cancer biology — Posted on 2019-12-18

1155 The Ty1 integrase nuclear localization signal is necessary and sufficient for retrotransposon targeting to tRNA genes

Asif-Laidin, A.; Conesa, C.; Bonnet, A.; Grison, C.; Adhya, I.; Menouni, R.; Fayol, H.; Palmic, N.; Acker, J.; Lesage, P.

10.1101/2019.12.18.879569 — molecular biology — Posted on 2019-12-18

1156 Systematic development of peptide inhibitors targeting the CXCL12/HMGB1 interaction

Sgrignani, J.; Cecchinato, V.; Fassi, E. M. A.; Dagostino, G.; Garofalo, M.; Danelon, G.; Grazioso, G.; Uguccioni, M.; Cavalli, A.

10.1101/2019.12.18.878504 — biochemistry — Posted on 2019-12-18

1157 Phenylephrine induces relaxation of longitudinal strips from small arteries of goat legs

Marconi, K. P.; Bharathi, B.; Venis, A. M.; Raj, R.; Amirtham, S. M.; Subramani, S.

10.1101/2019.12.18.881003 — physiology — Posted on 2019-12-18

1158 Hand Grip Strength, Cognitive Function and the Role of Cognitive Reserve: Results from a Sample of Community Dwelling Elderly in China

Yang, L.-S.; WEI, R.; LIU, K.-y.; TAO, F.-b.; XU, P.-r.; CHENG, B.-j.; SUN, L.; WANG, Q.-n.; FENG, Q.-w.; LI, X.-d.

10.1101/2019.12.18.881037 — neuroscience — Posted on 2019-12-18

1159 Pinging the Brain with Transcranial Magnetic Stimulation Reveals Cortical Reactivity in Time and Space

Ahn, S.; Frohlich, F.

10.1101/2019.12.18.880989 — neuroscience — Posted on 2019-12-18

1160 The characterization of a humanized rabbit anti-TNF α monoclonal antibody?A nationwide RA treatment drug study

wang, c.; Ni, x.; Liu, y.; Jin, z.; Xia, h.; N/A,

10.1101/2019.12.18.881029 — cell biology — Posted on 2019-12-18

1161 Disease associated protein-protein interaction network reconstruction based on comprehensive influence analysis

Zhu, F.; Li, F.; Ling, X.; Liu, Q.; Shen, B.

10.1101/2019.12.18.880997 — bioinformatics — Posted on 2019-12-18

1162 Machine learning goes wild: Using data from captive individuals to infer wildlife behaviour

Rast, W.; Kimmig, S.; Giese, L.; Berger, A.

10.1101/2019.12.18.881011 — animal behavior and cognition — Posted on 2019-12-18

1163 Multiplex PCR for simultaneous genotyping of kdr mutations V410L, V1,016I and F1,534C in Aedes aegypti (L.).

Villanueva-Segura, K.; Ponce-Garcia, G.; Lopez-Monroy, B.; Mora-Jasso, E. d. J.; Perales, L.; Gonzalez-Santillan, F. J.; Ontiveros-Zapata, K.; Davila-Barboza, J. A.; Flores, A. E.

10.1101/2019.12.17.880195 — molecular biology — Posted on 2019-12-18

1164 Abundances of transcripts, proteins, and metabolites in the cell cycle of budding yeast reveals coordinate control of lipid metabolism

Blank, H. M.; Papoulas, O.; Maitra, N.; Garge, R. K.; Kennedy, B. K.; Schilling, B.; Marcotte, E. M.; Polymenis, M.

10.1101/2019.12.17.880252 — systems biology — Posted on 2019-12-18

1165 Engineering combinatorial and dynamic decoders using synthetic immediate-early genes

Ravindran, P. T.; Wilson, M. Z.; Jena, S. G.; Toettcher, J. E.

10.1101/2019.12.17.880179 — synthetic biology — Posted on 2019-12-18

1166 Inferring the immune response from repertoire sequencing

Puelma Touzel, M.; Walczak, A. M.; Mora, T.

10.1101/2019.12.17.880138 — immunology — Posted on 2019-12-18

1167 Honeybee colony performance affected by crop diversity and farmland structure: a modelling framework

Horn, J.; Becher, M. A.; Johst, K.; Kennedy, P. J.; Osborne, J. L.; Radchuk, V.; Grimm, V.

10.1101/2019.12.17.880054 — ecology — Posted on 2019-12-18

1168 Coral bleaching susceptibility is predictive of subsequent mortality within but not between coral species

Matsuda, S.; Huffmyer, A.; Lenz, E. A.; Davidson, J.; Hancock, J.; Przybylowski, A.; Innis, T.; Gates, R. D.; Barott, K. L.

10.1101/2019.12.17.880161 — ecology — Posted on 2019-12-18

1169 Breaking a Strong Amide Bond: Structure and Properties of Dimethylformamidase.

Arya, C. K.; Yadav, S.; Fine, J.; Casanal, A.; Chopra, G.; Ramanathan, G.; Vinothkumar, K. R.; Subramanian, R.

10.1101/2019.12.17.879908 — biochemistry — Posted on 2019-12-18

1170 Limited phenological and pollinator-mediated isolation among selfing and outcrossing Arabidopsis lyrata populations

Gorman, C.; Bond, L.; van Kleunen, M.; Dorken, M.; Stift, M.

10.1101/2019.12.17.879361 — ecology — Posted on 2019-12-18

1171 A multi-structural finite element model to simulate atomic force microscopy nanoindentation of single cells

Marcotti, S.; Reilly, G. C.; Lacroix, D.

10.1101/2019.12.17.879114 — bioengineering — Posted on 2019-12-18

1172 Dynamic representation of taste-related decisions in the gustatory insular cortex of mice

Vincis, R.; Chen, K.; Czarnecki, L.; Chen, J.; Fontanini, A.

10.1101/2019.12.16.878553 — neuroscience — Posted on 2019-12-18

1173 Combining multi-omics and drug perturbation profiles to identify novel treatments that improve disease phenotypes in spinal muscular atrophy

Meijboom, K. E.; Volpato, V.; Monzon-Sandoval, J.; Hoolachan, J. M.; Hammond, S. M.; Abendroth, F.; de Jong, O. G.; Hazell, G.; Ahlskog, N.; Wood, M. J.; Webber, C.; Bowerman, M.

10.1101/2019.12.17.879353 — neuroscience — Posted on 2019-12-18

1174 To mock or not: a comprehensive comparison of mock IP and DNA input for ChIP-seq

Xu, J.; Kudron, M. M.; Victorsen, A.; Gao, J.; Ammouri, H. N.; Navarro, F. C. P.; Gevirtzman, L.; Waterston, R. H.; White, K. P.; Reinke, V.; Gerstein, M.

10.1101/2019.12.17.880013 — genomics — Posted on 2019-12-18

1175 Accurate brain age prediction with lightweight deep neural networks

Peng, H.; Gong, W.; Beckmann, C. F.; Vedaldi, A.; Smith, S. M.

10.1101/2019.12.17.879346 — neuroscience — Posted on 2019-12-18

1176 A model of flexible motor sequencing through thalamic control of cortical dynamics

Logiaco, L.; Abbott, L.; Escola, S.

10.1101/2019.12.17.880153 — neuroscience — Posted on 2019-12-18

1177 Characterization of a novel type III effector provides new insights into the allosteric activation and suppression of the Cas10 DNase

Lin, J.; Feng, M.; Zhang, H.; She, Q.

10.1101/2019.12.17.879585 — molecular biology — Posted on 2019-12-18

1178 A sensitive assay for dNTPs based on long synthetic oligonucleotides, EvaGreen dye, and inhibitor-resistant high-fidelity DNA polymerase

Purhonen, J.; Banerjee, R.; McDonald, A. E.; Fellman, V.; Kallijarvi, J.

10.1101/2019.12.17.879122 — molecular biology — Posted on 2019-12-18

1179 The stronger downregulation of in vitro and in vivo innate antiviral responses by a very virulent strain of infectious bursal disease virus (IBDV), compared to a classical strain, is mediated, in part, by the VP4 protein.

Dulwich, K. L.; Asfor, A. S. S.; Gray, A. G.; Giotis, E. S.; Skinner, M. A.; Broadbent, A. J.

10.1101/2019.12.17.879437 — microbiology — Posted on 2019-12-18

1180 High-resolution whole-genome analysis of sister-chromatid cohesion

Barre, F. X.; Espinosa, E.; Paly, E.

10.1101/2019.12.17.879379 — genomics — Posted on 2019-12-18

1181 When, why and how clonal diversity predicts future tumour growth

Noble, R. J.; Burley, J. T.; Le Sueur, C.; Hochberg, M. E.

10.1101/2019.12.17.879270 — cancer biology — Posted on 2019-12-18

1182 Floral vibrations by buzz-pollinating bees achieve higher frequency, velocity and acceleration than flight and defence vibrations

Pritchard, D. J.; Vallejo-Marin, M.

10.1101/2019.12.17.879981 — animal behavior and cognition — Posted on 2019-12-18

1183 Levonorgestrel modulates innate immune activation in human endocervical epithelium and monocytes during Chlamydia trachomatis infection

Eastman, A. J.; Liu, S.; Bell, J. D.

10.1101/2019.12.16.878710 — immunology — Posted on 2019-12-18

1184 Fast and highly efficient affinity enrichment of Azide-A-DSBSO cross-linked peptides.

Matzinger, M.; Kandioller, W.; Doppler, P.; Heiss, E. H.; Mechtler, K.

10.1101/2019.12.17.879601 — biochemistry — Posted on 2019-12-18

1185 Microplastic vector effects: are fish at risk when exposed via the trophic chain?

Bour, A.; Sturve, J.; Hojesjo, J.; Carney Almroth, B.

10.1101/2019.12.17.879478 — pharmacology and toxicology — Posted on 2019-12-18

1186 Dopaminergic Neurodegeneration Induced by Parkinson's Disease-Linked G2019S LRRK2 is Dependent on Kinase and GTPase Activity

Nguyen, A. P. T.; Tsika, E.; Kelly, K.; Chen, X.; Levine, N.; West, A. B.; Boularand, S.; Barneoud, P.; Moore, D. J.

10.1101/2019.12.17.879759 — neuroscience — Posted on 2019-12-18

1187 Astrocytes improve neuronal health after cisplatin treatment through mitochondrial transfer.

English, K.; Shepherd, A.; Nzor, N.-E.; Trinh, R.; Kavelaars, A.; Heijnen, C.

10.1101/2019.12.17.879924 — neuroscience — Posted on 2019-12-18

1188 Climbing fiber synapses rapidly inhibit neighboring Purkinje cells via ephaptic coupling

Han, K.-S.; Chen, C. H.; Khan, M.; Guo, C.; Regehr, W. G.

10.1101/2019.12.17.879890 — neuroscience — Posted on 2019-12-18

1189 Trajectories of brain volume change over 13 years in chronic schizophrenia.

Barth, C.; Jorgensen, K. N.; Wortinger, L. A.; Nerland, S.; Joensson, E. G.; Agartz, I.

10.1101/2019.12.17.879429 — neuroscience — Posted on 2019-12-18

1190 Phf15, a novel transcriptional repressor regulating inflammation in mouse microglia

Saijo, K.; Muroy, S. E.; Timblin, G. A.; Preininger, M. K.; Cedillo, P.

10.1101/2019.12.17.879940 — neuroscience — Posted on 2019-12-18

1191 Structural features recapitulate collective dynamics of inhibitory networks

Garg, S.; Singh, D.

10.1101/2019.12.17.879726 — neuroscience — Posted on 2019-12-18

1192 LGI1 downregulation increases neuronal circuit excitability

Lugara, E.; Kaushik, R.; Leite, M.; Chabrol, E.; Dityatev, A.; Lignani, G.; Walker, M. C.

10.1101/2019.12.17.879833 — neuroscience — Posted on 2019-12-18

1193 OCTAVVS: A graphical toolbox for high-throughput preprocessing and analysis of vibrational spectroscopy imaging data

Troein, C.; Siregar, S.; Op De Beeck, M.; Peterson, C.; Tunlid, A.; Persson, P.

10.1101/2019.12.17.879387 — biochemistry — Posted on 2019-12-18

1194 Method for identification of heme-binding proteins and quantification of their interactions

Bozinovic, N.; Noe, R.; Kanyavuz, A.; Lecerf, M.; Dimitrov, J. D.

10.1101/2019.12.17.879395 — biochemistry — Posted on 2019-12-18

1195 Gene expression data support the hypothesis that Isoetes rootlets are true roots and not modified leaves

Hetherington, A. J.; Emms, D. M.; Kelly, S.; Dolan, L.

10.1101/2019.12.16.878298 — plant biology — Posted on 2019-12-18

1196 Idioblasts as pathways for distributing water absorbed by leaf surfaces to the mesophyll in Capparis odoratissima

Losada, J. M.; Diaz, M.; Holbrook, N. M.

10.1101/2019.12.17.879577 — plant biology — Posted on 2019-12-18

1197 Therapeutic Targeting of 15-PGDH in Murine Idiopathic Pulmonary Fibrosis

Smith, J. N. P.; Witkin, M. D.; Jogasuria, A. P.; Christo, K. F.; Raffay, T. M.; Markowitz, S. D.; Desai, A. B.

10.1101/2019.12.16.878215 — pathology — Posted on 2019-12-18

1198 The hippocampus and dorso-lateral striatum link distinct types of memories through time and space, respectively

Ferbinteanu, J.

10.1101/2019.12.16.878470 — neuroscience — Posted on 2019-12-18

1199 Modulating brain networks with transcranial magnetic stimulation over the primary motor cortex: a concurrent TMS/fMRI study

Jung, J.; Bungert, A.; Bowtell, R.; Jackson, S. R.

10.1101/2019.12.16.878439 — neuroscience — Posted on 2019-12-18

1200 Insula Functional Connectivity in Schizophrenia

Sheffield, J. M.; Rogers, B. P.; Blackford, J. U.; Heckers, S.; Woodward, N. D.

10.1101/2019.12.16.878827 — neuroscience — Posted on 2019-12-18

1201 Variance and Scale-Free Properties of Resting-State BOLD Signal Alter after Fear Memory Acquisition and Extinction

Tetereva, A.; Kartashov, S.; Ivanitsky, A.; Martynova, O.

10.1101/2019.12.16.878587 — neuroscience — Posted on 2019-12-18

1202 Reduced cellular levels of DNA polymerase delta alter replication dynamics and enzymology, and impair lagging-strand processing

Koussa, N. C.; Smith, D. J.

10.1101/2019.12.17.879544 — molecular biology — Posted on 2019-12-18

1203 Transcriptome profiling of Variovorax paradoxus EPS under different growth conditions reveals regulatory and structural novelty in biofilm formation

Fredendall, R. J.; Stone, J. L.; Pehl, M. J.; Orwin, P. M.

10.1101/2019.12.17.879619 — microbiology — Posted on 2019-12-18

1204 Ultra-high throughput single-cell RNA sequencing by combinatorial fluidic indexing

Datlinger, P.; Rendeiro, A. F.; Boenke, T.; Krausgruber, T.; Barreca, D.; Bock, C.

10.1101/2019.12.17.879304 — genomics — Posted on 2019-12-18

1205 iucn_sim - Improved predictions of future extinctions using IUCN status assessments

Andermann, T.; Faurby, S.; Cooke, R.; Silvestro, D.; Antonelli, A.

10.1101/2019.12.16.878249 — evolutionary biology — Posted on 2019-12-18

1206 Small-scale spatial structure affects predator-prey dynamics and coexistence

Surendran, A.; Plank, M. J.; Simpson, M. J.

10.1101/2019.12.17.880104 — ecology — Posted on 2019-12-18

1207 In vivo microstimulation with cathodic and anodic asymmetric waveforms modulates spatiotemporal calcium dynamics in cortical neuropil and pyramidal neurons.

Steiger, K. C.; Eles, J. R.; Ludwig, K. A.; Kozai, T. D. Y.

10.1101/2019.12.16.878892 — bioengineering — Posted on 2019-12-18

1208 Antha-guided Automation of Darwin Assembly for the Construction of Bespoke Gene Libraries

Handal Marquez, P.; Koch, M.; Kestemont, D.; Arangundy-Franklin, S.; Pinheiro, V. B.

10.1101/2019.12.17.879486 — bioengineering — Posted on 2019-12-18

1209 Habitat loss in the restricted range of the endemic Ghanaian cichlid Limbochromis robertsi

Lamboj, A.; Lucanus, O.; Osei Darko, P.; Arroyo-Mora, J. P.; Kalacska, M.

10.1101/2019.12.16.877282 — ecology — Posted on 2019-12-18

1210 Theta rhythm supports hippocampus-dependent integrative encoding in schematic memory networks

Nicolas, B.; Sala-Padro, J.; Cucurell, D.; Saturnino, M.; Falip, M.; Fuentemilla, L.

10.1101/2019.12.16.874024 — neuroscience — Posted on 2019-12-18

1211 Rule adherence warps decision-making

Ebitz, B.; Tu, J. C.; Hayden, B.

10.1101/2019.12.16.878306 — neuroscience — Posted on 2019-12-18

1212 Reactive oxygen species (ROS) triggers unconventional secretion of antioxidants and Acb1

Cruz-Garcia, D.; Brouwers, N.; Malhotra, V.; Curwin, A. J.

10.1101/628321 — cell biology — Posted on 2019-12-18

1213 State-dependent differences in the frequency of TMS-evoked potentials

Stanfield, C. T.; Wiener, M.

10.1101/614826 — neuroscience — Posted on 2019-12-18

1214 Bayesian network analysis incorporating genetic anchors complements conventional Mendelian randomization approaches for exploratory analysis of causal relationships in complex data

Howey, R.; Shin, S.-Y.; Relton, C.; Davey Smith, G.; Cordell, H. J.

10.1101/639864 — genetics — Posted on 2019-12-18

1215 Parallel seed color adaptation during multiple domestication attempts of an ancient new world grain

Stetter, M. G.; Vidal-Villarejo, M.; Schmid, K. J.

10.1101/547943 — evolutionary biology — Posted on 2019-12-18

1216 Two distinct mechanisms of small molecule inhibition of LpxA acyltransferase essential for lipopolysaccharide biosynthesis

Han, W.; Ma, X.; Balibar, C. J.; Baxter Rath, C. M.; Benton, B.; Bermingham, A.; Casey, F.; Chie-Leon, B.; Cho, M.-K.; Frank, A. O.; Frommlet, A.; Ho, C.-M.; Lee, P. S.; Li, M.; Lingel, A.; Ma, S.; Merritt, H.; Ornelas, E.; de Pascale, G.; Prathapam, R.; Prosen, K. R.; Rasper, D.; Ruzin, A.; Sawyer, W.; Shaul, J.; Shen, X.; Shia, S.; Steffek, M.; Subramanian, S.; Vo, J.; Wang, F.; Wartchow, C.; Uehara, T.

10.1101/850305 — biochemistry — Posted on 2019-12-17

1217 sisterless A is required for the activation of Sex lethal in the germline

Goyal, R.; Baxter, E.; Van Doren, M.

10.1101/2019.12.17.880070 — developmental biology — Posted on 2019-12-18

1218 Benchmarking of computational error-correction methods for next-generation sequencing data

Mitchell, K.; Mandric, I.; Brito, J.; Wu, Q.; Knyazev, S.; Chang, S.; Martin, L.; Karlsberg, A.; Gerasimov, E.; Littman, R.; Hill, B. L.; Wu, N. C.; Yang, H.; Hsieh, K.; Chen, L.; Shabani, T.; Shabanets, G.; Yao, D.; Sun, R.; Schroeder, J.; Eskin, E.; Zelikovsky, A.; Skums, P.; Pop, M.; Mangul, S.

10.1101/642843 — bioinformatics — Posted on 2019-12-18

1219 Long-term vegetation changes in species-rich Nardus grasslands of Central Germany indicate eutrophication, recovery from acidification and management change as main drivers

Peppler-Lisbach, C.; Stanik, N.; Könitz, N.; Rosenthal, G.

10.1101/543512 — ecology — Posted on 2019-12-18

1220 The Minimum Environmental Perturbation Principle: A New Perspective on Niche Theory

Marsland, R.; Cui, W.; Mehta, P.

10.1101/531640 — ecology — Posted on 2019-12-18

1221 Improving the usability and comprehensiveness of microbial databases

Loeffler, C.; Karlsberg, A.; Martin, L. S.; Eskin, E.; Koslicki, D.; Mangul, S.

10.1101/497867 — bioinformatics — Posted on 2019-12-18

1222 Independent Yet Synergistic Roles of Synaptotagmin-1 and Complexin in Calcium Regulated Neuronal Exocytosis

Ramakrishnan, S.; Bera, M.; Coleman, J.; Rothman, J. E.; Krishnakumar, S. S.

10.1101/2019.12.16.878686 — neuroscience — Posted on 2019-12-18

1223 Spinal Microglia Contribute to Sustained Inflammatory Pain via Amplifying Neuronal Activity

Gu, N.; Yi, M.-H.; Murugan, M.; Xie, M.; Peng, J.; Eyo, U. B.; Dong, H.; Wu, L.-J.

10.1101/2019.12.16.878728 — neuroscience — Posted on 2019-12-18

1224 Distinct signatures of reward value and variance on spiking activity and functional interactions in monkey fronto-parietal areas

Taghizadeh, B.; Karimimehr, S.; Foley, N. C.; Cohanpour, M.; Semework, M.; Sheth, S. A.; Lashgari, R.; Gottlieb, J.

10.1101/2019.12.17.879262 — neuroscience — Posted on 2019-12-18

1225 Competitive Inhibition of Cortisol by Prostaglandins at the Ligand Binding Domain of Glucocorticoid Receptors

Schaper, C.

10.1101/851501 — molecular biology — Posted on 2019-12-18

1226 Near-complete Lokiarchaeota genomes from complex environmental samples using long and short read metagenomic analyses

Caceres, E. F.; Lewis, W. H.; Homa, F.; Martin, T.; Schramm, A.; Kjeldsen, K. U.; Ettema, T. J. G.

10.1101/2019.12.17.879148 — microbiology — Posted on 2019-12-18

1227 Bifidobacterium breve UCC2003 exopolysaccharide modulates the early life microbiota by acting as a dietary substrate

Puengel, D.; Treveil, A.; Dalby, M. J.; Caim, S.; Colquhoun, I. J.; Booth, C.; Ketskemety, J.; Korcsmaros, T.; van Sinderen, D.; Lawson, M. A.; Hall, L. J.

10.1101/2019.12.17.879130 — microbiology — Posted on 2019-12-18

1228 Does metal pollution affect stoichiometry of soil-litter food webs?

Asselman, M.; Sobczyk, L.; Weiner, J.; Scheu, S.; Rozen, A.

10.1101/2019.12.17.879205 — ecology — Posted on 2019-12-18

1229 Multi-Domain Translation between Single-Cell Imaging and Sequencing Data using Autoencoders

Yang, K. D.; Belyaeva, A.; Venkatachalapathy, S.; Damodaran, K.; Radhakrishnan, A.; Katcoff, A.; Shivashankar, G.; Uhler, C.

10.1101/2019.12.13.875922 — bioinformatics — Posted on 2019-12-18

1230 Characterization of SETD1A haploinsufficiency in humans and Drosophila defines a novel neurodevelopmental syndrome.

Kummeling, J.; Stremmelaar, D. E.; Raun, N.; Reijnders, M. R.; Willemsen, M. H.; Ruiterkamp-Versteeg, M.; Schepens, M.; Man, C. C.; Gilissen, C.; Cho, M. T.; McWalter, K.; Sinnema, M.; Wheless, J. W.; Simon, M. E.; Genetti, C. A.; Casey, A. M.; Terhal, P. A.; van der Smagt, J. `J; van Gassen, K. L.; Joset, P.; Bahr, A.; Steindl, K.; Rauch, A.; Keller, E.; Raas-Rothschild, A.; Koolen, D. A.; Agrawal, P. B.; Hoffman, T. L.; Powell-Hamilton, N. N.; Thiffault, I.; Engleman, K.; Zhou, D.; Bodamer, O.; Hoefele, J.; Riedhammer, K. M.; Schwaibold, E. M.; Tasic, V.; Schubert, D.; Top, D.; Pfundt, R.; H

10.1101/2019.12.17.879189 — genetics — Posted on 2019-12-18

1231 EPIGENE: genome wide transcription unit annotation using a multivariate probabilistic model of histone modifications

Sahu, A.; Li, N.; Dunkel, I.; Chung, H.-R.

10.1101/2019.12.17.878454 — bioinformatics — Posted on 2019-12-18

1232 LAVA: a streamlined visualization tool for longitudinal analysis of viral alleles

Lin, M. J.; Shean, R. C.; Makhsous, N.; Greninger, A.

10.1101/2019.12.17.879320 — bioinformatics — Posted on 2019-12-18

1233 Dual-task Interference in a Simulated Driving Environment: Serial or Parallel Processing?

Abbas-Zadeh, M.; Hossein-Zadeh, G.-A.; Vaziri-Pashkam, M.

10.1101/853119 — neuroscience — Posted on 2019-12-18

1234 Treating biomolecular interaction as an image classification problem - a case study on T-cell receptor-epitope recognition prediction

Moris, P.; De Pauw, J.; Postovskaya, A.; Ogunjimi, B.; Laukens, K.; Meysman, P.

10.1101/2019.12.18.880146 — bioinformatics — Posted on 2019-12-18

1235 FoodMine: Exploring Food Contents in Scientific Literature

Hooton, F.; Menichetti, G.; Barabasi, A.-L.

10.1101/2019.12.17.880062 — bioinformatics — Posted on 2019-12-18

1236 Maximizing prediction of orphan genes in assembled genomes

Seetharam, A. S.; Singh, U.; Li, J.; Bhandary, P.; Arendsee, Z.; Wurtele, E. S.

10.1101/2019.12.17.880294 — bioinformatics — Posted on 2019-12-18

1237 In silico screening of GMQ-like compounds reveals guanabenz and sephin1 as new allosteric modulators of acid-sensing ion channel 3

Callejo, G.; Pattison, L. A.; Greenhalgh, J. C.; Chakrabarti, S.; Andreopoulou, E.; Hockley, J. R.; Smith, E.; Rahman, T.

10.1101/704445 — pharmacology and toxicology — Posted on 2019-12-18

1238 The turning and barrier course: a standardized tool for eliciting freezing of gait and measuring the efficacy of deep brain stimulation

O'Day, J.; Syrkin-Nikolau, J.; Anidi, C.; Kidzinski, L.; Delp, S.; Bronte-Stewart, H.

10.1101/671479 — neuroscience — Posted on 2019-12-18

1239 Epilepsy and neurobehavioral abnormalities in mice with a KCNB1 pathogenic variant that alters conducting and non-conducting functions of KV2.1

Hawkins, N. A.; Misra, S. N.; Jurado, M.; Vierra, N. C.; Nguyen, K.; Wren, L.; George, A. L.; Trimmer, J. L.; Kearney, J. A.

10.1101/770206 — neuroscience — Posted on 2019-12-18

1240 Sleep-drive reprograms clock neuronal identity through CREB-binding protein induced PDFR expression

Klose, M. K.; Shaw, P.

10.1101/2019.12.12.874628 — neuroscience — Posted on 2019-12-18

1241 Attacks on genetic privacy via uploads to genealogical databases

Edge, M. D.; Coop, G.

10.1101/798272 — genomics — Posted on 2019-12-18

1242 Movement initiation and grasp representation in premotor and primary motor cortex mirror neurons

Jerjian, S. J.; Sahani, M.; Kraskov, A.

10.1101/2019.12.17.880237 — bioinformatics — Posted on 2019-12-18

1243 Phosphorylated Lamin A/C in the nuclear interior binds active enhancers associated with abnormal transcription in progeria

Ikegami, K.; Secchia, S.; Almakki, O.; Lieb, J. D.; Moskowitz, I. P.

10.1101/682260 — genetics — Posted on 2019-12-18

Yan, Y.; Li, Z.; Li, Y.; Wu, Z.; Yang, R.

10.1101/759589 — evolutionary biology — Posted on 2019-12-18

1245 Adaptation to low parasite abundance affects immune investment strategy and immunopathological responses of cavefish

Peuss, R.; Box, A. C.; Chen, S.; Wang, Y.; Tsuchiya, D.; Persons, J. L.; Kenzior, A.; Maldonado, E.; Krishnan, J.; Scharsack, J. P.; Slaughter, B. P.; Rohner, N.

10.1101/647255 — evolutionary biology — Posted on 2019-12-18

1246 Recurrent neural networks learn robust representations by dynamically balancing compression and expansion

Farrell, M. S.; Recanatesi, S.; Moore, T.; Lajoie, G.; Shea-Brown, E.

10.1101/564476 — neuroscience — Posted on 2019-12-18

1247 Prediction of pyrazinamide resistance in Mycobacterium tuberculosis using structure-based machine learning approaches.

Carter, J.; Walker, T. M.; Walker, A. S.; Whitfield, M.; Morlock, G. P.; Peto, T. E.; Posey, J. E.; Crook, D. W.; Fowler, P. W.

10.1101/518142 — microbiology — Posted on 2019-12-18

1248 Genetic variation of Aedes aegypti populations from Ecuador

Cevallos, V.; Benitez, A.; Coloma, J.; Carrazco, A.; Wang, C.; Holecheck, S.; Quiroga, C.; Castillo, A.; Tillis, B.; Ponce, P.

10.1101/2019.12.17.875591 — genetics — Posted on 2019-12-18

1249 Design of Experiments for Fine-Mapping Quantitative Trait Loci in Livestock Populations

Wittenburg, D.; Bonk, S.; Doschoris, M.; Reyer, H.

10.1101/2019.12.17.879106 — genetics — Posted on 2019-12-18

1250 Quantifying the importance of an inference model in Bayesian phylogenetics

Etienne, R. S.; Laudanno, G.; Bilderbeek, R. J.

10.1101/2019.12.17.879098 — evolutionary biology — Posted on 2019-12-18

1251 Probabilities of tree topologies with temporal constraints and diversification shifts

Didier, G.

10.1101/376756 — evolutionary biology — Posted on 2019-12-18

1252 Geometric cues stabilise long-axis polarisation of PAR protein patterns in C. elegans

Gessele, R.; Halatek, J.; Wuerthner, L.; Frey, E.

10.1101/451880 — biophysics — Posted on 2019-12-18

1253 Intelli-NGS: Intelligent NGS, a deep neural network-based artificial intelligence to delineate good and bad variant calls from IonTorrent sequencer data

Singh, A.; Bhatia, P.

10.1101/2019.12.17.879403 — bioinformatics — Posted on 2019-12-18

1254 Inhibition of tumor growth by a novel engineered chimeric toxin that cleaves activated mutant and wild-type RAS

Vidimar, V.; Beilhartz, G. L.; Park, M.; Biancucci, M.; Kieffer, M. B.; Gius, D. R.; Melnyk, R. A.; Satchell, K. J.

10.1101/2019.12.17.880187 — cancer biology — Posted on 2019-12-18

1255 Spen links RNA-mediated endogenous retrovirus silencing and X chromosome inactivation

Carter, A. C.; Xu, J.; Nakamoto, M. Y.; Wei, Y.; Shi, Q.; Broughton, J. P.; Ransom, R. C.; Salhotra, A.; Nagaraja, S. D.; Li, R.; Dou, D. R.; Yost, K. E.; Cho, S. W.; Mistry, A.; Longaker, M. T.; Batey, R. T.; Wuttke, D. S.; Chang, H.

10.1101/2019.12.17.879445 — genomics — Posted on 2019-12-18

1256 Aldehyde dehydrogenase 3 is an expanded gene family with adaptive roles in chickpea

Carmona-Molero, R.; Jimenez-Lopez, J. C.; Gil, J.; Millan, T.; Die, J. V.

10.1101/2019.12.17.879213 — genomics — Posted on 2019-12-18

1257 Visualizing 'omic feature rankings and log-ratios using Qurro

Fedarko, M. W.; Martino, C.; Morton, J. T.; Gonzalez, A.; Rahman, G.; Marotz, C. A.; Minich, J. J.; Allen, E. E.; Knight, R.

10.1101/2019.12.17.880047 — bioinformatics — Posted on 2019-12-18

1258 Intracellular photoswitchable neuropharmacology driven by luminescence from upconverting nanoparticles.

ZHAO, J.; ELLIS-DAVIES, G. C. R.

10.1101/2019.12.17.865261 — neuroscience — Posted on 2019-12-18

1259 ABHD4-dependent developmental anoikis protects the prenatal brain from pathological insults

Laszlo, Z.; Lele, Z.; Zoldi, M.; Miczan, V.; Mogor, F.; Simon, G. M.; Mackie, K.; Kacskovics, I.; Cravatt, B. F.; Katona, I.

10.1101/2019.12.17.879551 — developmental biology — Posted on 2019-12-18

1260 Transcriptome and Proteome analysis of Hemidactylus frenatus during initial stages of tail regeneration

Pawan, S.; Banu, S.; Idris, M. M.

10.1101/2019.12.17.879718 — developmental biology — Posted on 2019-12-18

1261 Enhancing generating and collecting efficiency of single particle upconverting luminescence at low-level power excitation

Ma, C.; Shan, C.; Park, K.; Mok, A. T.; Yang, X.

10.1101/2019.12.17.879858 — biophysics — Posted on 2019-12-18

1262 Structural and functional characterization of oligomeric states of proteins in RecFOR pathway

Chaudhary, S. K.; Elayappan, M.; Jeyakanthan, J.; Sekar, K.

10.1101/2019.12.17.877662 — biophysics — Posted on 2019-12-18

1263 SurA is a "Groove-y" Chaperone That Expands Unfolded Outer Membrane Proteins

Marx, D. C.; Plummer, A. M.; Faustino, A. M.; Roskopf, M. A.; Leblanc, M. J.; Devlin, T.; Lessen, H. J.; Majumdar, A.; Amann, B. T.; Fleming, P. J.; Krueger, S.; Fried, S. D.; Fleming, K. G.

10.1101/2019.12.17.878660 — biophysics — Posted on 2019-12-18

1264 Accurate and simultaneous identification of differential expression and splicing using hierarchical Bayesian analysis

Karlebach, G.; Hansen, P.; Veiga, D. F. T.; Steinhaus, R.; Danis, D.; Li, S.; Anczukow, O.; Robinson, P. N.

10.1101/2019.12.16.878884 — bioinformatics — Posted on 2019-12-18

1265 A non-linear system patterns Rab5 GTPase on the membrane

Cezanne, A.; Lauer, J.; Solomatina, A.; Sbalzarini, I. F.; Zerial, M.

10.1101/2019.12.17.880203 — biochemistry — Posted on 2019-12-18

1266 A PI3K-WIPI2 positive feedback loop allosterically activates LC3 lipidation in autophagy

Fracchiolla, D.; Chang, C.; Hurley, J. H.; Martens, S.

10.1101/2019.12.18.880591 — biochemistry — Posted on 2019-12-18

1267 The Tung Tree (Vernicia Fordii) Genome Provides A Resource for Understanding Genome Evolution and Oil Improvement

Zhang, L.; liu, M.; Long, H.; Dong, W.; Pasha, A.; Esteban, E.; Li, W.; Yang, X.; Li, Z.; Song, A.; Ran, D.; Zhao, G.; Zeng, Y.; Chen, H.; Zou, M.; Li, J.; Liang, F.; Xie, M.; Hu, J.; Wang, D.; Cao, H.; Provart, N. J.; Zhang, L.; Tan, X.

10.1101/2019.12.17.877803 — bioinformatics — Posted on 2019-12-18

1268 A Novel Neoantigen Discovery Approach based on Chromatin High Order Conformation

Shi, Y.; Zhang, M.; Meng, L.; Su, X.; Shang, X.; Li, Q.; Lin, M.; Zou, X.; Luo, Q.; Zhai, Y.; He, K.; Wang, L.; Chen, C.; Cui, X.; Wang, N.; He, J.; Yu, Y.; Wu, Y.; Da, L.; Cai, T. W.; Han, Z.-g.

10.1101/539387 — bioinformatics — Posted on 2019-12-18

1269 CHASMplus reveals the scope of somatic missense mutations driving human cancers

Tokheim, C.; Karchin, R.

10.1101/313296 — bioinformatics — Posted on 2019-12-18

1270 Host prion protein expression levels impact prion tropism for the spleen

Beringue, V.; TIXADOR, P.; ANDREOLETTI, O.; REINE, F.; Castille, J.; Lai, T.-L.; Le Dur, A.; Laisne, A.; HERZOG, L.; PASSET, B.; Rezaei, H.; VILOTTE, J.-L.; LAUDE, H.

10.1101/2019.12.17.879676 — pathology — Posted on 2019-12-17

1271 Clinical correlates of sarcopenia and falls in Parkinson's disease

Lima, D. P.; de Almeida, S. B.; Bonfadini, J. d. C.; de Luna, J. R. G.; de Alencar, M. S.; Pinheiro-Neto, E. B.; Viana-Junior, A. B.; Veras, S. R. O.; Sobreira-Neto, M. A.; Roriz-Filho, J. d. S.; Braga-Neto, P.

10.1101/2019.12.17.879668 — neuroscience — Posted on 2019-12-17

1272 Accuracy of a deep convolutional neural network in the detection of myopic macular diseases using swept-source optical coherence tomography

Sogawa, T.; Tabuchi, H.; Nagasato, D.; Masumoto, H.; Ikuno, Y.; Ohsugi, H.; Ishitobi, N.; Mitamura, Y.

10.1101/2019.12.17.879650 — bioengineering — Posted on 2019-12-17

1273 Zika and dengue viruses infecting wild-caught mosquitoes in an environmental protection area in Brazil

Barrio-Nuevo, K. M.; Medeiros-Sousa, A. R.; Ceretti-Junior, W.; Fernandes, A.; Rocco, I. M.; Cunha, M. S.; Luchs, A.; Mucci, L. F.; de Souza, R. P.; Marrelli, M.

10.1101/2019.12.17.879643 — zoology — Posted on 2019-12-17

1274 Antioxidant, anti-enzymatic, antimicrobial and cytotoxic properties of Euphorbia tirucalli L.

altamimi, m.; Jaradat, N.; Al-Lahham, S.; Al-masri, M.; Bsharat, A.; Alsaleh, R.; Sabobeh, R.

10.1101/2019.12.17.879692 — pharmacology and toxicology — Posted on 2019-12-17

1275 Transcriptome sequencing and screening of genes related to sex determination of Trichosanthes kirilowii Maxim.

jie, x.; xiuqin, h.; jinkai, z.; guanjie, j.; zhen, w.

10.1101/2019.12.17.879635 — genomics — Posted on 2019-12-17

1276 Management of a Walnut Germplasm Collection: Which of SSR or SNP Markers Are Most Suitable to Preserve Biodiversity?

Bernard, A.; Barreneche, T.; Donkpegan, A.; Lheureux, F.; Dirlewanger, E.

10.1101/2019.12.17.879627 — genetics — Posted on 2019-12-17

1277 Automatic and fast encoding of representational uncertainty underlies probability distortion

Ren, X.; Luo, H.; Zhang, H.

10.1101/2019.12.17.879684 — neuroscience — Posted on 2019-12-17

1278 Deciphering the mechanism of inhibition of SERCA1a by sarcolipin using molecular simulations

Mouawad, L.; Beswick, V.; Jamin, N.; Montigny, C.; Quiniou, E.; Barbot, T.

10.1101/2019.12.17.879825 — biophysics — Posted on 2019-12-17

1279 Improving characterization of understudied human microbiomes using targeted phylogenetics

Rosa, B. A.; Mihindukulasuriya, K.; Hallsworth-Pepin, K.; Wollam, A.; Martin, J.; Snowden, C.; Dunne, W. M.; Weinstock, G.; Burnham, C.-A. D.; Mitreva, M.

10.1101/2019.12.16.879023 — microbiology — Posted on 2019-12-17

1280 14-3-3β paralog is inhibited by acetylation during differentiation to the osteogenic lineage.

Frontini-Lopez, Y. R.; Gojanovich, A. D.; Uhart, M.; Bustos, D. M.

10.1101/2019.12.17.879155 — cell biology — Posted on 2019-12-17

1281 Dynamic rotation of the protruding domain enhances the infectivity of norovirus

Song, C.; Takai-Todaka, R.; Miki, M.; Haga, K.; Fujimoto, A.; Ishiyama, R.; Oikawa, K.; Yokoyama, M.; Miyazaki, N.; Iwasaki, K.; Murakami, K.; Katayama, K.; Murata, K.

10.1101/2019.12.16.878785 — pathology — Posted on 2019-12-17

1282 Transcriptional regulation of MGE progenitor proliferation by PRDM16 controls cortical GABAergic interneuron production

Harwell, C.; Turrero Garcia, M.; Baizabal, J.-M.; Tran, D.; Peixoto, R.; Wang, W.; Xie, Y.; Adam, M.; Brito, S.; Booker, M.; Tolstorukov, M.

10.1101/2019.12.17.879510 — neuroscience — Posted on 2019-12-17

1283 Structural clusters of histone H3 and H4 residues regulate chronological lifespan in Saccharomyces cerevisiae

Ngubo, M.; Reid, J. L.; Patterton, H. -G.

10.1101/2019.12.16.878983 — molecular biology — Posted on 2019-12-17

1284 Effects of single mutations on protein stability are Gaussian distributed

Razban, R. M.; Shakhnovich, E. I.

10.1101/2019.12.17.879536 — biophysics — Posted on 2019-12-17

1285 Modelling the effects of environmental heterogeneity within the lung on the tuberculosis life-cycle

Pitcher, M. J.; Bowness, R.; Dobson, S.; Eftimie, R.; Gillespie, S. H.

10.1101/2019.12.12.871269 — systems biology — Posted on 2019-12-17

1286 Genome-wide expression analysis of immune receptors in hot pepper reveals an autonomous NLR cluster in higher plants

Lee, H.-Y.; Mang, H.; Seo, Y.-E.; Oh, S.; Kim, S.-B.; Park, E.; Choi, D.

10.1101/2019.12.16.878959 — plant biology — Posted on 2019-12-17

1287 Mountain stoneflies may tolerate warming streams: evidence from organismal physiology and gene expression

Hotaling, S.; Shah, A. A.; McGowan, K. L.; Tronstad, L. M.; Giersch, J. J.; Finn, D. S.; Woods, H. A.; Dillon, M. E.; Kelley, J. L.

10.1101/2019.12.16.878926 — physiology — Posted on 2019-12-17

1288 APOE4 status is related to differences in memory-related brain function in asymptomatic older adults: Baseline analysis of the PREVENT-AD task fMRI dataset

Rabipour, S.; Rajagopal, S.; Yu, E.; Pasvanis, S.; Breitner, J.; Rajah, M. N.

10.1101/2019.12.11.871681 — neuroscience — Posted on 2019-12-17

1289 Sexual Differences in Mitochondrial Proteins in Rat Cerebral Microvessels: A Proteomic Approach

Chandra, P. K.; Cikic, S.; Harman, J. C.; Rutkai, I.; Katakam, P. V. G.; Guidry, J.; Gidday, J. M.; Busija, D. W.

10.1101/2019.12.17.879254 — neuroscience — Posted on 2019-12-17

1290 Characterization of 100 extended major histocompatibility complex haplotypes in Indonesian cynomolgus macaques

Shortreed, C. G.; Wiseman, R. W.; Karl, J. A.; Bussan, H. E.; Baker, D. A.; Prall, T. M.; Haj, A. K.; Moreno, G. K.; Penedo, M. C. T.; O'Connor, D. H.

10.1101/2019.12.16.878421 — genetics — Posted on 2019-12-17

1291 Macromolecular and electrical coupling between inner hair cells in the rodent cochlea

Jean, P.; Anttonen, T.; Michanski, S.; Garcia de Diego, A. M.; Steyer, A. M.; Neef, A.; Oestreicher, D.; Kroll, J.; Nardis, C.; Pangrsic, T.; Moebius, W.; Ashmore, J.; Wichmann, C.; Moser, T.

10.1101/2019.12.17.879767 — neuroscience — Posted on 2019-12-17

1292 Association of Sonic Hedgehog with the Extracellular Matrix Requires its Putative Zinc-Peptidase Activity

Jaegers, C.; Roelink, H.

10.1101/2019.12.17.880039 — developmental biology — Posted on 2019-12-17

1293 Mechanics of multi-centrosomal clustering in bipolar mitotic spindles

Chatterjee, S.; Sarkar, A.; Zhu, J.; Khodjakov, A.; Mogilner, A.; Paul, R.

10.1101/2019.12.17.879817 — cell biology — Posted on 2019-12-17

1294 SEQing: web-based visualization of Arabidopsis thaliana iCLIP and RNA-seq data in an interactive python framework

Lewinski, M.; Bramkamp, Y.; Köster, T.; Staiger, D.

10.1101/2019.12.17.865873 — bioinformatics — Posted on 2019-12-17

1295 Serum biochemistry suggests grey squirrels (Sciurus carolinensis) have poorer physiological condition in urban settings

Schmidt, C.; Treberg, J. R.; Kinnunen, R. P.; Garroway, C. J.

10.1101/2019.12.16.878702 — physiology — Posted on 2019-12-17

1296 Prediction of Multi peptides Vaccination from VP10,VP21, VP51 against Reverse Transcriptase Human immunodeficiency Viruses Using Immuno-informatics Approach

Idris, S. A. A.; Mohamed, I. I.; Siddig, H. A. e.; Abd albagi, S. o.; Khalil Abuzeid, N. M.

10.1101/2019.12.16.877555 — bioinformatics — Posted on 2019-12-17

1297 Reconstructing the complex evolutionary history of the fused Aco2 gene in fission yeast.

Sun, S.; Roy, S. W.; Anderson, N. M.

10.1101/2019.12.16.879015 — bioinformatics — Posted on 2019-12-17

1298 Contrast-Enhanced, Molecular Imaging of Vascular Inflammation in the Mouse Model by Simultaneous PET/MRI

Du, S.; Ng, T.; House, A.; Tang, T.; Zheng, L.; Tu, C.; Peake, J.; Espiritu, I.; Ma, K.-L.; Pinkerton, K.; Jacobs, R.; Louie, A.

10.1101/2019.12.16.878652 — bioengineering — Posted on 2019-12-17

1299 How do backward walking ants (Cataglyphis velox) cope with navigational uncertainty?

Schwarz, S.; Clement, L.; Gkanias, E.; Wystrach, A.

10.1101/2019.12.16.877704 — animal behavior and cognition — Posted on 2019-12-17

1300 Enhancing vs. inhibiting semantic performance with repetitive transcranial magnetic stimulation over the anterior temporal lobe: frequency- and task- specific effects

Jung, J.; Lambon Ralph, M.

10.1101/2019.12.16.878256 — neuroscience — Posted on 2019-12-17

1301 ppGpp functions as an alarmone in metazoa

Ito, D.; Kawamura, H.; Oikawa, A.; Ihara, Y.; Shibata, T.; Nakamura, N.; Asano, T.; Kawabata, S.-I.; Suzuki, T.; Masuda, S.

10.1101/2019.12.16.878942 — molecular biology — Posted on 2019-12-17

1302 Identification of human tendon cell populations in healthy and diseased tissue using combined single cell transcriptomics and proteomics

Kendal, A. R.; Layton, T.; Al-Mossawi, H.; Brown, R.; Loizou, C.; Rogers, M.; Sharp, R.; Dakin, S.; Appleton, L.; Carr, A.

10.1101/2019.12.09.869933 — cell biology — Posted on 2019-12-17

1303 Strategy in wheat-Fusarium dual-genome RNA-seq data processing

Liu, Z.; Li, Y.; Pan, Y.; Wang, L.; Ouellet, T.; Fobert, P.

10.1101/2019.12.16.878124 — bioinformatics — Posted on 2019-12-17

1304 Cleavage of a pathogen apoplastic protein by plant subtilases activates immunity

Wang, S.; Xing, R.; Wang, Y.; Shu, H.; Fu, S.; Paulus, J.; Schuster, M.; Saunders, D.; Win, J.; Vleeshouwers, V.; Zheng, X.; van der Hoorn, R. A. L.; Kamoun, S.; Dong, S.

10.1101/2019.12.16.878272 — plant biology — Posted on 2019-12-17

1305 Molecular structures and mechanisms of DNA break processing in mouse meiosis

Yamada, S.; Hinch, A. G.; Kamido, H.; Zhang, Y.; Edelmann, W.; Keeney, S.

10.1101/2019.12.17.876854 — molecular biology — Posted on 2019-12-17

1306 Systematic humanization of the yeast cytoskeleton discerns functionally replaceable from divergent human genes

Garge, R. K.; Laurent, J. M.; Kachroo, A. H.; Marcotte, E. M.

10.1101/2019.12.16.878751 — evolutionary biology — Posted on 2019-12-17

1307 Ancient microRNA profiles of a 14,300-year-old canid are taxonomically informative and give glimpses into gene regulation from the Pleistocene

Fromm, B.; Tarbier, M.; Smith, O.; Dalen, L.; Gilbert, T. M.; Friedlander, M. R.

10.1101/2019.12.16.877761 — evolutionary biology — Posted on 2019-12-17

1308 Patterns of gene flow across multiple anthropogenic infrastructures: insights from a multi-species approach

Remon, J.; Moulherat, S.; Cornuau, J. H.; Gendron, L.; Richard, M.; Baguette, M.; Prunier, J. G.

10.1101/2019.12.16.877670 — ecology — Posted on 2019-12-17

1309 The tempest in a cubic millimeter: Image-based refinements necessitate the reconstruction of 3D microvasculature from a large series of damaged alternately-stained histological sections

Lobachev, O.

10.1101/2019.12.17.877738 — bioinformatics — Posted on 2019-12-17

1310 TMATCH: A New Algorithm for Protein Alignments using amino-acid hydrophobicities

Cavanaugh, D. P.; Chittur, K.

10.1101/2019.12.16.878744 — bioinformatics — Posted on 2019-12-17

1311 Depth in convolutional neural networks solves scene segmentation

Seijdel, N.; Tsakmakidis, N.; de Haan, E. H.; Bohte, S. M.; Scholte, H. S.

10.1101/2019.12.16.877753 — neuroscience — Posted on 2019-12-17

1312 Yeast ATM and ATR use different mechanisms to spread histone H2A phosphorylation around a DNA double-strand break

Li, K.; Bronk, G.; Kondev, J.; Haber, J. E.

10.1101/2019.12.17.877266 — molecular biology — Posted on 2019-12-17

1313 Separating Functions of the Phage-Encoded Quorum-Sensing-Activated Antirepressor Qtip

Silpe, J. E.; Bridges, A. A.; Huang, X.; Coronado, D. R.; Duddy, O. P.; Bassler, B. L.

10.1101/2019.12.16.877910 — microbiology — Posted on 2019-12-17

1314 Comparison of Yersinia enterocolitica DNA methylation at ambient and host temperatures

Van Hofwegen, D. J.; Hovde, C. J.; Minnich, S. A.

10.1101/2019.12.16.878991 — microbiology — Posted on 2019-12-17

1315 Resistance to dieldrin evolution in African malaria vectors is driven by interspecific and interkaryotypic introgression

Grau-Bove, X.; Tomlinson, S.; O'Reilly, A. O.; Harding, N. J.; Miles, A.; Kwiatkowski, D.; Donnelly, M. J.; Weetman, D.; The Anopheles gambiae 1000 Genomes Consortium,

10.1101/2019.12.17.879775 — evolutionary biology — Posted on 2019-12-17

1316 Neuropeptide F receptor acts in the Drosophila prothoracic gland to regulate growth and developmental timing

Kannangara, J. R.; Henstridge, M. A.; Parsons, L. M.; Kondo, S.; Mirth, C. K.; Warr, C. G.

10.1101/2019.12.16.878967 — developmental biology — Posted on 2019-12-17

1317 Control of assembly of extra-axonemal structures: the paraflagellar rod of trypanosomes

Alves, A. A.; Bezerra, M. J. R.; de Souza, W.; Vaughan, S.; Cunha-e-Silva, N. L.; Sunter, J. D.

10.1101/2019.12.17.879841 — cell biology — Posted on 2019-12-17

1318 Mass measurements of polyploid lymphocytes reveal that growth is not size limited but depends strongly on cell cycle

Mu, L.; Kang, J. H.; Olcum, S.; Payer, K. R.; Calistri, N. L.; Kimmerling, R. J.; Manalis, S. R.; Miettinen, T. P.

10.1101/2019.12.17.879080 — cell biology — Posted on 2019-12-17

1319 Positional isomers of a non-nucleoside substrate differentially affect myosin function

Debold, E.; Woodward, M.; Ostrander, E.; Jeong, S.; Liu, X.; Scott, B.; Unger, M.; Chen, J.; Venkataraman, D.

10.1101/2019.12.17.879809 — biophysics — Posted on 2019-12-17

1320 Simulation-based comprehensive study of batch effects in metabolomics studies

Yu, M.; Roszkowska, A.; Pawliszyn, J.

10.1101/2019.12.16.878637 — bioinformatics — Posted on 2019-12-17

1321 Sequence Comparison without Alignment: The SpaM approaches

Morgenstern, B.

10.1101/2019.12.16.878314 — bioinformatics — Posted on 2019-12-17

1322 Confronting p-hacking: addressing p-value dependence on sample size

Gomez de Mariscal, E.; Sneider, A.; Jayatilaka, H.; Phillip, J. M.; Wirtz, D.; Munoz-Barrutia, A.

10.1101/2019.12.17.878405 — bioinformatics — Posted on 2019-12-17

1323 Opening the black box of fish tracking using acoustic telemetry

Baktoft, H.; Gjelland, K. O.; Okland, F.; Rehage, J. S.; Rodemann, J. R.; Corujo, R. S.; Viadero, N.; Thygesen, U. H.

10.1101/2019.12.16.877688 — animal behavior and cognition — Posted on 2019-12-17

1324 Effects of early life glucocorticoid exposure on metabolism in zebrafish (Danio rerio) larvae

van den Bos, R.

10.1101/2019.12.16.877654 — physiology — Posted on 2019-12-17

1325 A Population Modelling Approach to Studying Age-Related Effects on Excitation-Contraction Coupling in Human Cardiomyocytes

Dokuchaev, A.; Khamzin, S.; Solovyova, O.

10.1101/2019.12.17.877514 — physiology — Posted on 2019-12-17

1326 Separable functions of Tof1/Timeless in intra-S-checkpoint signalling, replisome stability and DNA topological stress.

Westhorpe, R.; Keszthelyi, A.; Minchell, N. E.; Jones, D.; Baxter, J.

10.1101/2019.12.17.877811 — molecular biology — Posted on 2019-12-17

1327 Bacterial killing by complement requires direct anchoring of Membrane Attack Complex precursor C5b-7

Doorduijn, D. J.; Bardoel, B. W.; Heesterbeek, D. A.; Ruyken, M.; Benn, G.; Parsons, E. S.; Hoogenboom, B.; Rooijakkers, S. H.

10.1101/2019.12.17.877639 — immunology — Posted on 2019-12-17

1328 Novel Variants in COL4A3 and COL4A4 are Causes of Alport Syndrome in Rio Grande do Norte, Brazil

de Araujo, W. C.; Falcao, R. M.; Uchoa, R.; Garcia, C. A.; de Souza, J. E. S.; Jeronimo, S. M. B.

10.1101/2019.12.17.878918 — genomics — Posted on 2019-12-17

1329 A polarized nucleus-cytoskeleton-ECM connection controls collective migration and cardioblasts number in Drosophila

Dondi, C.; Bertin, B.; Daponte, J.-P.; Wojtowicz, I.; Jagla, K.; Junion, G.

10.1101/2019.12.17.879932 — developmental biology — Posted on 2019-12-17

1330 EPIGENE: genome wide transcription unit annotation using a multivariate probabilistic model of histone modifications

Sahu, A.; Li, N.; Dunkel, I.; Chung, H.-R.

10.1101/2019.12.17.878454 — bioinformatics — Posted on 2019-12-17

1331 Homoeologous gene expression and co-expression network analyses and evolutionary inference in allopolyploids

Hu, G.; Grover, C.; Arick, M. A.; Liu, M.; Peterson, D.; Wendel, J.

10.1101/2019.12.16.878900 — bioinformatics — Posted on 2019-12-17

1332 Adaptive shifts in gene regulation underlie a developmental delay in thermogenesis in high-altitude deer mice

Velotta, J. P.; Robertson, C. E.; Schweizer, R. M.; McClelland, G. B.; Cheviron, Z. A.

10.1101/2019.12.17.880112 — evolutionary biology — Posted on 2019-12-17

1333 L-type voltage-gated calcium channel agonists improve hearing loss and modify ribbon synapse morphology in the zebrafish model of Usher Syndrome Type 1

Koleilat, A.; Dugdale, J. A.; Christenson, T. A.; Bellah, J. L.; Lambert, A. M.; Masino, M. A.; Ekker, S. C.; Schimmenti, L. A.

10.1101/2019.12.16.878231 — neuroscience — Posted on 2019-12-17

1334 Dissociable roles of cortical excitation-inhibition balance during patch-leaving versus value-guided decisions

Kaiser, L. F.; Gruendler, T. O. J.; Speck, O.; Luettgau, L.; Jocham, G.

10.1101/2019.12.15.877019 — neuroscience — Posted on 2019-12-17

1335 A CRISPR screen identifies UFMylation and TRAMP-like complexes required for hepatitis A virus infection

Kulsuptrakul, J.; Wang, R.; Meyers, N. L.; Ott, M.; Puschnik, A. S.

10.1101/2019.12.15.877100 — microbiology — Posted on 2019-12-17

1336 Histone methyltransferase DOT1L controls state-specific identity during B cell differentiation

Aslam, M. A.; Alemdehy, M. F.; Kwesi-Maliepaard, E. M.; Caganova, M.; Pardieck, I. N.; van den Brand, T.; Muhaimi, F. I.; van Welsem, T.; de Rink, I.; Song, J.-Y.; de Wit, E.; Arens, R.; Rajewsky, K.; Jacobs, H.; van Leeuwen, F.

10.1101/826370 — immunology — Posted on 2019-12-17

1337 Adaptive introgression across semipermeable species boundaries between local Helicoverpa zea and invasive Helicoverpa armigera moths

Valencia-Montoya, W. A.; Elfekih, S.; North, H. L.; Meier, J. I.; Warren, I. A.; Tay, W. T.; Gordon, K. H. J.; Specht, A.; Paula-Moraes, S. V.; Rane, R.; Walsh, T. K.; Jiggins, C. D.

10.1101/2019.12.15.877225 — evolutionary biology — Posted on 2019-12-17

1338 Effect of EBV-transformation on Oxidative Phosphorylation Physiology in Human Cell lines

Crawford, D. L.; Weinstein, R. N.

10.1101/2019.12.16.878025 — evolutionary biology — Posted on 2019-12-17

1339 ARP-T1 is a ciliary protein associated with a novel ciliopathy in inherited basal cell cancer, Bazex-Dupre-Christol Syndrome

Park, H.-S.; Pich, C.; Chiticariu, E.; Bachmann, D.; Papanastasi, E.; Blanchard, G.; Plomann, M.; Morice-Picard, F.; Vabres, P.; Smahi, A.; Huber, M.; Hohl, D.

10.1101/2019.12.16.877498 — cancer biology — Posted on 2019-12-17

1340 Don't Dismiss Logistic Regression: The Case for Sensible Extraction of Interactions in the Era of Machine Learning

Levy, J. J.; O'Malley, J.

10.1101/2019.12.15.877134 — bioinformatics — Posted on 2019-12-17

1341 Deep Docking - a Deep Learning Approach for Virtual Screening of Big Chemical Datasets

Gentile, F.; Agrawal, V.; Hsing, M.; Ban, F.; Norinder, U.; Gleave, M. E.; Cherkasov, A.

10.1101/2019.12.15.877316 — bioinformatics — Posted on 2019-12-17

1342 Geometric cues stabilise long-axis polarisation of PAR protein patterns in C. elegans

Gessele, R.; Halatek, J.; Wuerthner, L.; Frey, E.

10.1101/451880 — biophysics — Posted on 2019-12-17

1343 GPCRmd uncovers the dynamics of the 3D-GPCRome

Rodriguez-Espigares, I.; Torrens-Fontanals, M.; Tiemann, J. K. S.; Aranda-Garcia, D.; Ramirez-Anguita, J. M.; Stepniewski, T. M.; Worp, N.; Varela-Rial, A.; Morales-Pastor, A.; Medel Lacruz, B.; Pandy-Szekeres, G.; Mayol, E.; Giorgino, T.; Carlsson, J.; Deupi, X.; Filipek, S.; Gomez-Tamayo, J. C.; Gonzalez, A.; Gutierrez-de-Teran, H.; Jimenez, M.; Jespers, W.; Kapla, J.; Khelashvili, G.; Kolb, P.; Latek, D.; Marti-Solano, M.; Matricon, P.; Matsoukas, M.-T.; Miszta, P.; Olivella, M.; Perez-Benito, L.; Rios, S.; Rodriguez-Torrecillas, I.; Sallander, J.; Sztyler, A.; Vaidehi, N.; Vasile, S.; Wein

10.1101/839597 — biophysics — Posted on 2019-12-17

1344 A hierarchical framework for segmenting movement paths

Getz, W. M.

10.1101/819763 — ecology — Posted on 2019-12-17

1345 Randomly primed, strand-switching MinION-based sequencing for the detection and characterization of cultured RNA viruses

Young, K. T.; Lahmers, K. K.; Sellers, H. S.; Stallknecht, D. E.; Poulson, R. L.; Saliki, J. T.; Tompkins, S. M.; Padykula, I.; Siepker, C.; Howerth, E. W.; Todd, M.; Stanton, J. B.

10.1101/2019.12.16.875872 — pathology — Posted on 2019-12-17

1346 Intravital quantification of absolute cytoplasmic B cell calcium reveals dynamic signaling across B cell differentiation stages

Ulbricht, C.; Leben, R.; Rakhymzhan, A.; Kirchhoff, F.; Nitschke, L.; Radbruch, H.; Niesner, R. A.; Hauser, A. E.

10.1101/2019.12.13.872820 — immunology — Posted on 2019-12-17

1347 Size, not temperature, drives cyclopoid copepod predation of invasive mosquito larvae

Russell, M. C.; Qureshi, A.; Wilson, C. G.; Cator, L. J.

10.1101/839480 — ecology — Posted on 2019-12-17

1348 FYN tyrosine kinase, a downstream target of receptor tyrosine kinases, modulates anti-glioma immune responses

Comba, A.; Dunn, P. J.; Argento, A. E.; Kadiyala, P.; Ventosa, M.; Patel, P.; Zamler, D.; Nunez, F. J.; Zhao, L.; Castro, M. G.; Lowenstein, P. R.

10.1101/608505 — cancer biology — Posted on 2019-12-17

1349 Using Ethereum blockchain to store and query pharmacogenomics data via smart contracts

Gursoy, G.; Brannon, C.; Gerstein, M.

10.1101/2019.12.16.878488 — bioinformatics — Posted on 2019-12-17

1350 Cardiomyocyte-Specific Deletion of GCN5L1 in Mice Limits Ex Vivo Cardiac Functional Decline in Response to a High Fat Diet

Thapa, D.; Manning, J. R.; Stoner, M. W.; Zhang, M.; Xie, B.; Sack, M. N.; Scott, I.

10.1101/805283 — physiology — Posted on 2019-12-17

1351 Identifying differential cell populations in flow cytometry data accounting for marker frequency

Yue, A.; Chauve, C.; Libbrecht, M.; Brinkman, R.

10.1101/837765 — bioinformatics — Posted on 2019-12-17

1352 Intrinsic dynamics enhance temporal stability of stimulus representation along a visual cortical hierarchy

Piasini, E.; Soltuzu, L.; Caramellino, R.; Balasubramanian, V.; Zoccolan, D.

10.1101/822130 — neuroscience — Posted on 2019-12-17

1353 Attenuated directed exploration during reinforcement learning in gambling disorder

Wiehler, A.; Chakroun, K.; Peters, J.

10.1101/823583 — neuroscience — Posted on 2019-12-17

1354 Repurposing the Streptococcus mutans CRISPR-Cas9 System to Understand Essential Gene Function

Shields, R. C.; Walker, A. R.; Maricic, N.; Chakraborty, B.; Underhill, S. A.; Burne, R. A.

10.1101/791483 — microbiology — Posted on 2019-12-17

1355 Division of labor promotes the spread of information in colony emigrations by the ant Temnothorax rugatulus

Valentini, G.; Masuda, N.; Shaffer, Z.; Hanson, J. R.; Sasaki, T.; Walker, S. I.; Pavlic, T. P.; Pratt, S. C.

10.1101/791996 — animal behavior and cognition — Posted on 2019-12-17

1356 Inhibition of IL-1beta secretion and mitochondria respiration by arsenite which acts on myocardial ischemia-reperfusion injury

Li, M.; Mei, Y.; Liu, J.; Fan, K.; Zhang, X.; Gu, X.; Xu, J.; Li, Y.; Mi, Y.

10.1101/751297 — pharmacology and toxicology — Posted on 2019-12-17

1357 An acute session of motor imagery training induces use-dependent plasticity.

Ruffino, C.; Gaveau, J.; Papaxanthis, C.; Lebon, F.

10.1101/716357 — neuroscience — Posted on 2019-12-17

1358 Long-term alterations in brain and behavior after postnatal Zika virus infections in infant macaques

Raper, J.; Kovacs-Balint, Z.; Mavinger, M.; Gumber, S.; Burke, M. W.; Habib, J.; Mattingly, C.; Fair, D.; Earl, E.; Feczko, E.; Styner, M.; Jean, S.; Cohen, J.; Suthar, M.; Sanchez, M. M.; Alvarado, M. C.; Chahroudi, A.

10.1101/788794 — neuroscience — Posted on 2019-12-17

1359 Identification of the main glutamine and glutamate transporters in Staphylococcus aureus and their impact on c-di-AMP production

Zeden, M. S.; Kviatkovski, I.; Schuster, C. F.; Thomas, V. C.; Fey, P. D.; Grundling, A.

10.1101/754309 — microbiology — Posted on 2019-12-17

1360 Discovery of genes required for body axis and limb formation by global identification of conserved retinoic acid regulated enhancers and silencers

Berenguer, M.; Meyer, K. F.; Yin, J.; Duester, G.

10.1101/778191 — developmental biology — Posted on 2019-12-17

1361 An Open Source Mesh Generation Platform for Biophysical Modeling Using Realistic Cellular Geometries

Lee, C. T.; Laughlin, J. G.; Moody, J. B.; Amaro, R. E.; McCammon, J. A.; Holst, M. J.; Rangamani, P.

10.1101/765453 — biophysics — Posted on 2019-12-17

1362 Hierarchical Markov Random Field model captures spatial dependency in gene expression, demonstrating regulation via the 3D genome

Zhou, N.; Friedberg, I.; Kaiser, M. S.

10.1101/2019.12.16.878371 — bioinformatics — Posted on 2019-12-17

1363 High fat diet worsens pathology and impairment in an Alzheimers mouse model, but not by synergistically decreasing cerebral blood flow

Bracko, O.; Vinarcsik, L. K.; Cruz Hernandez, J. C.; Ruiz-Uribe, N. E.; Haft-Javaherian, M.; Falkenhain, K.; Ramanauskaite, E. M.; Ali, M.; Mohapatra, A.; Swallow, M. A.; Njiru, B. N.; Muse, V. P.; contributors, S. C.; Michelucci, P.; Nishimura, N.; Schaffer, C. B.

10.1101/2019.12.16.878397 — neuroscience — Posted on 2019-12-17

1364 Stimulus-modality independent activation of the brain network for language

Arana, S. L.; Marquand, A. F.; Hulten, A.; Hagoort, P.; Schoffelen, J. M.

10.1101/714998 — neuroscience — Posted on 2019-12-17

1365 Modular prophage interactions driven by capsule serotype select for capsule loss under phage predation

Moura de Sousa, J. A.; Buffet, A.; Haudiquet, M.; Rocha, E. P. C.; Rendueles, O.

10.1101/2019.12.17.878363 — microbiology — Posted on 2019-12-17

1366 Global analysis reveals complex demographic responses of mammals to climate change

Paniw, M.; James, T.; Archer, C. R.; Roemer, G.; Levin, S.; Compagnoni, A.; Che-Castaldo, J.; Bennett, J. M.; Mooney, A.; Childs, D. Z.; Ozgul, A.; Jones, O. R.; Burns, J. H.; Beckerman, A. P.; Patwary, A.; Sanchez-Gassen, N.; Knight, T. M.; Salguero-Gomez, R.

10.1101/2019.12.16.878348 — ecology — Posted on 2019-12-17

1367 Comparative evaluation of full-length isoform quantification from RNA-Seq

Sarantopoulou, D.; Nayak, S.; Brooks, T. G.; Lahens, N. F.; Grant, G. R. R.

10.1101/698605 — bioinformatics — Posted on 2019-12-17

1368 MethylNet: An Automated and Modular Deep Learning Approach for DNA Methylation Analysis

Levy, J. J.; Titus, A. J.; Petersen, C. L.; Chen, D.; Salas, L. A.; Christensen, B. C.

10.1101/692665 — bioinformatics — Posted on 2019-12-17

1369 Engineered full-length Fibronectin-based hydrogels sequester and present growth factors to promote regenerative responses in vitro and in vivo

Trujillo, S.; Gonzalez-Garcia, C.; Rico, P.; Reid, A.; Windmill, J.; Dalby, M. J.; Salmeron-Sanchez, M.

10.1101/687244 — bioengineering — Posted on 2019-12-17

1370 Temporal changes in post-alighting resistance to Rhopalosiphum padi (bird cherry-oat aphid) in ancestral wheats

Simon, A. L.; Smart, L. E.; Hammond-Kosack, K. E.; Field, L. M.; Aradottir, G. I.

10.1101/2019.12.16.877589 — zoology — Posted on 2019-12-17

1371 3D mesh processing using GAMer 2 to enable reaction-diffusion simulations in realistic cellular geometries

Lee, C. T.; Laughlin, J. G.; Angliviel de La Beaumelle, N.; Amaro, R.; McCammon, J. A.; Ramamoorthi, R.; Holst, M. J.; Rangamani, P.

10.1101/534479 — systems biology — Posted on 2019-12-17

1372 Ectopic overexpression of abiotic stress-induced rice annexin, OsAnn5 potentiates tolerance to abiotic stresses

Boyidi, P.; Vikas, T. S.; Botta, H. K.; Yadav, D.; Pulugurtha, B. K.

10.1101/2019.12.16.869131 — plant biology — Posted on 2019-12-17

1373 Seven-year-olds recall non-adjacent dependencies after overnight retention

Schaadt, G.; Paul, M.; Muralikrishnan, R.; Männel, C.; Friederici, A. D.

10.1101/670257 — neuroscience — Posted on 2019-12-17

1374 Transcriptome-based design of antisense inhibitors re-sensitizes CRE E. coli to carbapenems

Aunins, T. R.; Erickson, K.; Chatterjee, A.

10.1101/2019.12.16.878389 — microbiology — Posted on 2019-12-17

1375 Patterns of thermal adaptation in a worldwide plant pathogen: local diversity and plasticity reveal two-tier dynamics

Boixel, A.-L.; Chelle, M.; Suffert, F.

10.1101/2019.12.16.877696 — ecology — Posted on 2019-12-17

1376 Interleukin-12 elicits a non-canonical response in B16 melanoma cells to enhance survival

Byrne-Hoffman, C.; Deng, W.; McGrath, O.; Wang, P.; Rojanasakul, Y.; Klinke, D. J.

10.1101/608828 — cancer biology — Posted on 2019-12-17

1377 Bacterial cell wall integrity surveillance is connected to peptidoglycan biosynthesis by the essential phosphorylation of ReoM

Wamp, S.; Rutter, Z. J.; Rismondo, J.; Jennings, C. E.; Moeller, L.; Lewis, R. J.; Halbedel, S.

10.1101/2019.12.16.877605 — microbiology — Posted on 2019-12-17

1378 Bacterial persisters in long-term infection: emergence and fitness in a complex host environment

Bartell, J. A.; Cameron, D. R.; Mojsoska, B.; Haagensen, J. A.; Sommer, L. M.; Lewis, K.; Molin, S.; Johansen, H. K.

10.1101/561589 — microbiology — Posted on 2019-12-17

1379 Promoter-anchored chromatin interactions predicted from genetic analysis of epigenomic data

Wu, Y.; Qi, T.; Wang, H.; Zhang, F.; Zheng, Z.; Phillips-Cremins, J. E.; Deary, I. J.; McRae, A. F.; Wray, N. R.; Zeng, J.; Yang, J.

10.1101/580993 — genetics — Posted on 2019-12-17

1380 The genome polishing tool POLCA makes fast and accurate corrections in genome assemblies

Zimin, A. V.; Salzberg, S. L.

10.1101/2019.12.17.864991 — bioinformatics — Posted on 2019-12-17

1381 Precision in a sea of profusion: Myelin replacement triggered by single-cell cortical demyelination

Snaidero, N.; Schifferer, M.; Mezydlo, A.; Kerschensteiner, M.; Misgeld, T.

10.1101/2019.12.16.877597 — neuroscience — Posted on 2019-12-17

1382 Dietary sugar inhibits satiation by decreasing the central processing of sweet taste

May, C. E.; Rosander, J.; Gottfried, J.; Dennis, E.; Dus, M.

10.1101/2019.12.16.877613 — neuroscience — Posted on 2019-12-17

1383 The dynamic neural code of the retina for natural scenes

Maheswaranathan, N.; McIntosh, L. T.; Tanaka, H.; Grant, S.; Kastner, D. B.; Melander, J.; Brezovec, L.; Nayebi, A.; Wang, J.; Ganguli, S.; Baccus, S. A.

10.1101/340943 — neuroscience — Posted on 2019-12-17

1384 Viperin binds STING and enhances the type-I interferon response following dsDNA detection

Crosse, K. M.; Monson, E. A.; Dumbrepatil, A. B.; Smith, M.; Tseng, Y.-Y.; Van der Hoek, K. H.; Revill, P. A.; Tscharke, D. C.; Marsh, E. N. G.; Beard, M. R.; Helbig, K. J.

10.1101/493098 — immunology — Posted on 2019-12-17

1385 Intriguing density dependence but problematic birth rates in Greaver et al.'s study of a black rhinoceros population.

Law, P. R.; Linklater, W. L.; Gedir, J.

10.1101/039453 — ecology — Posted on 2019-12-17

1386 Arabidopsis XTH4 and XTH9 contribute to wood cell expansion and secondary wall formation

Kushwah, S.; Banasiak, A.; Nishikubo, N.; Derba-Maceluch, M.; Majda, M.; Endo, S.; Kumar, V.; Gomez, L.; Gorzsas, A.; McQueen-Mason, S.; Braam, J.; Sundberg, B.; Mellerowicz, E. J.

10.1101/2019.12.16.877779 — developmental biology — Posted on 2019-12-17

1387 Fine-scale fronts as hotspots of fish aggregation in the open ocean

Baudena, A.; Ser-Giacomi, E.; d'Onofrio, D.; Capet, X.; Cotte, C.; Cherel, Y.; d'Ovidio, F.

10.1101/2019.12.16.877571 — biophysics — Posted on 2019-12-17

1388 Modulation of cortical slow oscillatory rhythm by GABAB receptors: an experimental and computational study

Perez-Zabalza, M.; Reig, R.; Manrique, J.; Jercog, D.; Winograd, M.; Parga, N.; Sanchez-Vives, M. V.

10.1101/2019.12.14.866442 — neuroscience — Posted on 2019-12-17

1389 Quorum sensing regulation in Erwinia carotovora affects development of Drosophila melanogaster infected larvae

Vieira, F. J. D.; Nadal-Jimenez, P.; Teixeira, L.; Xavier, K. B.

10.1101/2019.12.13.876318 — microbiology — Posted on 2019-12-17

1390 Amyloid-like aggregates cause lysosomal defects in neurons via gain-of-function toxicity

Schaefer, T.; Riera-Tur, I.; Hornburg, D.; Mishra, A.; Fernandez-Mosquera, L.; Raimundo, N.; Mann, M.; Baumeister, W.; Klein, R.; Meissner, F.; Fernandez-Busnadiego, R.; Dudanova, I.

10.1101/2019.12.16.877431 — cell biology — Posted on 2019-12-17

1391 Noninvasive optical detection of Granzyme B from natural killer cells using enzyme-activated fluorogenic probes

Janiszewski, T.; Kolt, S.; Kaiserman, D.; Snipas, S. S.; Li, S.; Kulbacka, J.; Saczko, J.; Bovenschen, N.; Salvesen, G.; Drag, M.; Bird, P.; Kasperkiewicz, P.

10.1101/2019.12.16.875070 — biochemistry — Posted on 2019-12-17

1392 AMPAR/TARP stoichiometry differentially modulates channel properties

Miguez-Cabello, F.; SGR, ; Sanchez-Fernandez, N.; RETIC Oftared, ; Yefimenko Nosova, N.; Gasull Casanova, X.; Gratacos-Batlle, E.; Soto, D.

10.1101/2019.12.16.877506 — neuroscience — Posted on 2019-12-17

1393 The secretory fate of flavivirus NS1 in mosquito cells is influenced by the caveolin binding domain

Rosales Ramirez, R.; Ludert, J. E.

10.1101/2019.12.16.879031 — molecular biology — Posted on 2019-12-17

1394 Mutation of a PER2 phosphodegron perturbs the circadian phosphoswitch

Masuda, S.; Narasimamurthy, R.; Yoshitane, H.; Kim, J. K.; Fukada, Y.; Virshup, D. M.

10.1101/2019.12.16.876615 — molecular biology — Posted on 2019-12-17

1395 Reconstitution of the Human tRNA Splicing Endonuclease Complex: insight into the regulation of pre-tRNA cleavage.

Hayne, C. K.; Schmidt, C. A.; Matera, G. E.; Stanley, R. E.

10.1101/2019.12.16.878546 — molecular biology — Posted on 2019-12-17

1396 Pooled analysis of radiation hybrids identifies loci for growth and drug action in mammalian cells

Khan, A. H.; Lin, A.; Wang, R. T.; Bloom, J. S.; Lange, K.; Smith, D. J.

10.1101/2019.12.16.877365 — genetics — Posted on 2019-12-17

1397 Stutter: a Transient Dynamic Instability Phase that is Strongly Associated with Catastrophe

Mahserejian, S. M.; Scripture, J. P.; Mauro, A. J.; Lawrence, E. J.; Jonasson, E. M.; Murray, K. S.; Li, J.; Gardner, M. K.; Alber, M.; Zanic, M.; Goodson, H. V.

10.1101/2019.12.16.878603 — cell biology — Posted on 2019-12-17

1398 SNAPSwitch: A Molecular Sensor to Quantify the Localization of Proteins, DNA and Nanoparticles in Cells

FitzGerald, L. I.; Aurelio, L.; Chen, M.; Yuen, D.; Graham, B.; Johnston, A. P. R.

10.1101/2019.12.16.877043 — cell biology — Posted on 2019-12-17

1399 Genome-wide CRISPR screens identify essential cell growth mediators in BRAF-inhibitor resistant melanoma

Li, Z.; Wang, B.; Gu, S.; Jiang, P.; Sahu, A.; Chen, C.-H.; Han, T.; Shi, S.; Wang, X.; Traugh, N.; Liu, H.; Liu, Y.; Wu, Q.; Brown, M.; Xiao, T.; Boland, G.; Liu, S.

10.1101/2019.12.16.876631 — cancer biology — Posted on 2019-12-17

1400 Active mucus-cilia hydrodynamic coupling drives self-organisation of human bronchial epithelium

Loiseau, E.; Gsell, S.; Nommick, A.; Jomard, C.; Gras, D.; Chanez, P.; D'Ortona, U.; Kodjabachian, L.; Favier, J.; Viallat, A.

10.1101/2019.12.16.878108 — biophysics — Posted on 2019-12-17

1401 Structural dynamics of isolated myosin motor domains encode differences in their mechanochemical cycles

Porter, J. R.; Meller, A.; Zimmerman, M. I.; Greenberg, M. J.; Bowman, G. R.

10.1101/2019.12.16.878264 — biophysics — Posted on 2019-12-17

1402 The Dynamic Landscape of Transcription Initiation in Yeast Mitochondria

Sohn, B.-K.; Basu, U.; Lee, S.-W.; Cho, H.; Shen, J.; Deshpande, A.; Patel, S. S.; Kim, H.

10.1101/2019.12.16.877878 — biophysics — Posted on 2019-12-17

1403 Spatial distribution and research trend of illegal activities and the factors associated with wild mammal population declines in protected areas

Rija, A. A.; Critchlow, R.; Thomas, C.; Beale, C.

10.1101/2019.12.16.877944 — zoology — Posted on 2019-12-16

1404 Effects of Endophytic Fungus MF23 on Dendrobium nobile Lindl. in an artificial primary environment

Chen, X. y.; Xu, X.; Li, Q.; Li, B.; Ding, G.; Guo, S.

10.1101/2019.12.16.878066 — genetics — Posted on 2019-12-16

1405 Effects of land-use change and related pressures on alien and native subsets of island communities

Sanchez Ortiz, K.; Taylor, K. J. M.; De Palma, A.; König, C.; Pysek, P.; Weigelt, P.; Essl, F.; Purvis, A.

10.1101/2019.12.16.878041 — ecology — Posted on 2019-12-16

1406 Shell morphology, genital and radula structures of new invasive giant African land snail species, Achatina fulica Bowdich, 1822, Achatina albopicta E.A. Smith (1878) and Achatina reticulata Pfeiffer 1845 (Gastropoda:Achatinidae) in southwest Nigeria

Odaibo, A. B.; Olayinka, S. O.

10.1101/2019.12.16.877977 — ecology — Posted on 2019-12-16

1407 Species and habitat mapping in two dimensions and beyond. Structure-from-Motion Multi-View Stereo photogrammetry for the conservation community.

DeBell, L.; Duffy, J. P.; McKinley, T. J.; Anderson, K.

10.1101/2019.12.16.878033 — ecology — Posted on 2019-12-16

1408 Dose old age lead to gluttony? Effects of aging on predation and locomotion in the assassin bug Amphibolus venator.

Miyatake, T.; Matsumura, K.; Iwaya, M.; Nagaya, N.; Fujisawa, R.

10.1101/2019.12.16.877993 — animal behavior and cognition — Posted on 2019-12-16

1409 A long noncoding RNA acts as a post-transcriptional regulator of heat shock protein 70 kDa synthesis in the cold hardy Diamesa tonsa under heat shock

Lencioni, V.; Bernabo, P.; Viero, G.

10.1101/2019.12.16.877985 — zoology — Posted on 2019-12-16

1410 EffectorK, a comprehensive resource to mine for pathogen effector targets in the Arabidopsis proteome

Gonzalez-Fuente, M.; Carrere, S.; Monachello, D.; Marsella, B. G.; Cazale, A.-C.; Zischek, C.; Mitra, R. M.; Reze, N.; Cottret, L.; Mukhtar, M. S.; Lurin, C.; Noel, L. D.; Peeters, N.

10.1101/2019.12.16.878074 — plant biology — Posted on 2019-12-16

1411 Physiological predictors of competitive performance in CrossFit(R) athletes

Brea, L.; Martinez-Gomez, R.; Valenzuela, P.; Gil-Cabrera, J.; Montalvo-Perez, A.; Talavera, E.; Lucia, A.; Moral-Gonzalez, S.; Barranco-Gil, D.

10.1101/2019.12.16.877928 — physiology — Posted on 2019-12-16

1412 Differential involvement of EEG oscillatory components in sameness vs. spatial-relation visual reasoning tasks

Alamia, A.; Canhuang, L.; Ricci, M.; Kim, J.; Serre, T.; Vanrullen, R.

10.1101/2019.12.16.877829 — neuroscience — Posted on 2019-12-16

1413 Malaria transmission assisted by interaction between Plasmodium α-tubulin-1 and Anopheles FREP1 protein

Zhang, G.; Niu, G.; Perez, L.; Wang, X.; Li, J.

10.1101/2019.12.16.878082 — microbiology — Posted on 2019-12-16

1414 Genes influenced by MEF2C contribute to neurodevelopmental disease via gene expression changes that affect multiple types of cortical excitatory neurons

Cosgrove, D.; Whitton, L.; Fahey, L.; O Broin, P.; Donohoe, G.; Morris, D. W.

10.1101/2019.12.16.877837 — genomics — Posted on 2019-12-16

1415 Characterization of the novel clinical isolate X-4 containing a new tp0548 sequence-type

Liu, D.; Tong, M.-L.; Liu, L.-L.; Lin, L.-R.; Lin, Y.; Yang, T.-C.

10.1101/2019.12.16.877886 — genetics — Posted on 2019-12-16

1416 Effect of EBV-transformation on Oxidative Phosphorylation Physiology in Human Cell lines

Crawford, D. L.; Weinstein, R. N.

10.1101/2019.12.16.878025 — evolutionary biology — Posted on 2019-12-16

1417 Biodiversity clock and conservation triangle: Integrative platform for biodiversity monitoring, evaluation, and preemptive conservation intervention

Nair, J. R.; M, V.; Rajan, S. C.; N.P, S.; K, A.; V, S.; Dominic, L.; Mathew, S. J.; Unnikrishnan, A.; Dadhwal, V. K.

10.1101/2019.12.16.877969 — ecology — Posted on 2019-12-16

1418 Predation by Himalayan Wolves: Understanding conflict, culture and co-existence amongst Indo-Tibetan community and large carnivores in High Himalaya

LYNGDOH, S.; Habib, B.

10.1101/2019.12.16.877936 — ecology — Posted on 2019-12-16

1419 Phospho-regulation of the Shugoshin - Condensin interaction at the centromere in budding yeast

Metwaly, G.; Wu, Y.; Peplowska, K.; Rohrl, J.; Soh, Y.-M.; Burmann, F.; Gruber, S.; Storchova, Z.

10.1101/2019.12.16.877894 — cell biology — Posted on 2019-12-16

1420 The drivers of West Nile virus human illness: fine scale dynamic effects of weather, mosquito infection, social, and biological conditions

Karki, S.; Brown, W. M.; Uelmen, J.; Ruiz, M. O.; Smith, R. L.

10.1101/2019.12.16.877951 — bioinformatics — Posted on 2019-12-16

1421 Nanoparticle-based targeted delivery of pentagalloyl glucose reverses elastase-induced abdominal aortic aneurysm and restores aorta to the healthy state in mice

Dhital, S.; Vyavahare, N.

10.1101/2019.12.16.878017 — bioengineering — Posted on 2019-12-16

1422 Re-evaluation of lysyl hydroxylation in the collagen triple helix: lysyl hydroxylase 1 and prolyl 3-hydroxylase 3 have site-differential and collagen type-dependent roles in lysine hydroxylation.

Ishikawa, Y.; Taga, Y.; Zientek, K.; Mizuno, N.; Salo, A. M.; Semenova, O.; Tufa, S.; Keene, D. R.; Holden, P.; Mizuno, K.; Myllyharju, J.; Bächinger, H. P.

10.1101/2019.12.16.877852 — biochemistry — Posted on 2019-12-16

1423 Antigen and G-Protein Coupled Receptor signaling differentially control CD8 T cell motility immediately before and after virus clearance in a primary infection

Lambert-Emo, K.; Reilly, E. C.; Sportiello, M.; Topham, D. J.

10.1101/2019.12.16.877845 — immunology — Posted on 2019-12-16

1424 Crowdsourced RNA design discovers diverse, reversible, efficient, self-contained molecular sensors

Andreasson, J.; Gotrik, M.; Wu, M. J.; Wayment-Steele, H.; Kladwang, W.; Portela, F.; Wellington-Oguri, R.; Players, E.; Das, R.; Greenleaf, W.

10.1101/2019.12.16.877183 — synthetic biology — Posted on 2019-12-16

1425 Microglial Calcium Signaling is Attuned to Neuronal Activity

Umpierre, A. D.; Bystrom, L. L.; Ying, Y.; Liu, Y. U.; Wu, L.-J.

10.1101/2019.12.16.876060 — neuroscience — Posted on 2019-12-16

1426 L-type voltage-gated calcium channel agonists improve hearing loss and modify ribbon synapse morphology in the zebrafish model of Usher Syndrome Type 1

Koleilat, A.; Dugdale, J. A.; Christenson, T. A.; Bellah, J. L.; Lambert, A. L.; Masino, M. A.; Ekker, S. C.; Schimmenti, L. A.

10.1101/2019.12.16.878231 — neuroscience — Posted on 2019-12-16

1427 From zygote to a multicellular soma: body size affects optimal growth strategies under cancer risk

Erten, E. Y.; Kokko, H.

10.1101/2019.12.16.877118 — evolutionary biology — Posted on 2019-12-16

1428 Physiological networks governing salinity tolerance potentials in Gossypium hirsutum germplasm

Cushman, K. R.; Pabuayon, I. C.; Hinze, L. L.; Sweeney, M. T.; de los Reyes, B. G.

10.1101/2019.12.16.877787 — physiology — Posted on 2019-12-16

1429 Disassembly of Tau fibrils by the human Hsp70 disaggregation machinery generates small seeding-competent species

Nachman, E.; Wentink, A.; Madiona, K.; Bousset, L.; Katsinelos, T.; Kampinga, H.; McEwan, W. A.; Jahn, T. R.; Melki, R.; Mogk, A.; Bukau, B.; Nussbaum-Krammer, C.

10.1101/2019.12.16.876888 — molecular biology — Posted on 2019-12-16

1430 Revisiting microbe-metabolite interactions: doing better than random

Morton, J.; McDonald, D.; Aksenov, A.; Nothias-Scaglia, L.-F.; Foulds, J.; Quinn, R. A.; Badri, M.; Swenson, T.; Van Goethem, M.; Northen, T.; Vazquez-Baeza, Y.; Wang, M.; Bokulich, N.; Watters, A.; Song, S. J.; Bonneau, R.; Dorrestein, P.; Knight, R.

10.1101/2019.12.10.871905 — bioinformatics — Posted on 2019-12-16

1431 Opponent processes in visual memories: a model of attraction and repulsion in navigating insects' mushroom bodies.

Le Moel, F.; Wystrach, A.

10.1101/2019.12.16.877449 — animal behavior and cognition — Posted on 2019-12-16

1432 A novel ribosomal protein 20 variant in a family with unexplained colorectal cancer and polyposis

Thompson, B. A.; Snow, A. K.; Koptiuch, C.; Kohlmann, W. K.; Mooney, R.; Johnson, S.; Huff, C.; Yu, Y.; Teerlink, C. C.; Feng, B.-J.; Neklason, D. W.; Cannon-Albright, L. A.; Tavtigian, S. V.

10.1101/2019.12.16.877084 — genetics — Posted on 2019-12-16

1433 Copper Induces Zebrafish Central Neural System Myelin Defects: the Regulatory Mechanisms in Wnt/Notch-hoxb5b Signaling and Underlying DNA Methylation

Zhang, T.; Guan, P.; Zhao, G.; Fang, Y.; Fu, H.; Gui, J.; Li, G.; Liu, J.-X.

10.1101/2019.12.16.877860 — developmental biology — Posted on 2019-12-16

1434 ARP-T1 is a ciliary protein associated with a novel ciliopathy in inherited basal cell cancer, Bazex-Dupre-Christol Syndrome

Park, H.-S.; Pich, C.; Chiticariu, E.; Bachmann, D.; Papanastasi, E.; Blanchard, G.; Plomann, M.; Morice-Picard, F.; Vabres, P.; Smahi, A.; Huber, M.; Hohl, D.

10.1101/2019.12.16.877498 — cancer biology — Posted on 2019-12-16

1435 DNA Chisel, a versatile sequence optimizer

Zulkower, V.; Rosser, S.

10.1101/2019.12.16.877480 — synthetic biology — Posted on 2019-12-16

1436 Secreted microbial metabolites modulate gut immunity and inflammatory tone

Giri, R.; Hoedt, E. C.; Shamsunnahar, K.; McGuckin, M. A.; Morrison, M.; Capon, R. J.; Begun, J.; Cuiv, P. O.

10.1101/2019.12.16.861872 — microbiology — Posted on 2019-12-16

1437 Sleep-drive reprograms clock neuronal identity through CREB-binding protein induced PDFR expression

Klose, M. K.; Shaw, P.

10.1101/2019.12.12.874628 — neuroscience — Posted on 2019-12-16

1438 Transglutaminase-2 facilitates extracellular vesicle-mediated establishment of the metastatic niche

Shinde, A.; Paez, J. S.; Libring, S. M.; Hopkins, K.; Solorio, L.; Wendt, M.

10.1101/2019.12.16.875948 — cancer biology — Posted on 2019-12-16

1439 Emergence of single cell mechanical behavior and polarity within epithelial monolayers drives collective cell migration

Jain, S.; Cachoux, V.; Sankara, G.; de Beco, S.; D'Alessandro, J.; Cellerin, V.; Chen, T.; Heuze, M.; Marcq, P.; Mege, R.-M.; Kabla, A.; Lim, C. T.; Ladoux, B.

10.1101/2019.12.16.875567 — biophysics — Posted on 2019-12-16

1440 Laws of diversity and variation in microbial communities

Grilli, J.

10.1101/680454 — ecology — Posted on 2019-12-16

1441 S-conLSH: Alignment-free gapped mapping of noisy long reads

Chakraborty, A.; Morgenstern, B.; Bandyopadhyay, S.

10.1101/801118 — bioinformatics — Posted on 2019-12-16

1442 Aberrant cocoons found on honey bee comb cells are found to be Osmia cornifrons (Radoszkowski) (Hymenoptera Megachilidae)

Posada-Florez, F.; Bloetscher, B.; Lopez, D.; Pava-Ripoll, M.; Rogers, C.; Evans, J. D.

10.1101/2019.12.16.875856 — zoology — Posted on 2019-12-16

1443 Tuba activates Cdc42 during neuronal polarization downstream of the small GTPase Rab8a

Urrutia, P. J.; Bodaleo, F.; Borquez, D. A.; Rozes-Salvador, V.; Villablanca, C.; Conde, C.; Fukuda, M.; Gonzalez-Billault, C.

10.1101/2019.12.16.876011 — cell biology — Posted on 2019-12-16

1444 Longitudinal wastewater sampling in buildings reveals temporal dynamics of metabolites

Evans, E.; Dai, C.; Isazadeh, S.; Park, S.; Ratti, C.; Alm, E. J.

10.1101/2019.12.16.870576 — bioinformatics — Posted on 2019-12-16

1445 Required characteristics for modeling languages in systems biology: A software engineering perspective

Schölzel, C.; Blesius, V.; Ernst, G.; Dominik, A.

10.1101/2019.12.16.875260 — systems biology — Posted on 2019-12-16

1446 Rapid Alkalinization Factor (RALF) gene family genomic structure and transcriptional regulation during host-pathogen crosstalk in Fragaria vesca and Fragariax ananassa strawberry

Negrini, F.; O'Grady, K.; Hyvonen, M.; Folta, K.; Baraldi, E.

10.1101/858928 — plant biology — Posted on 2019-12-16

1447 Randomly primed, strand-switching MinION-based sequencing for the detection and characterization of cultured RNA viruses

Young, K. T.; Lahmers, K. K.; Sellers, H. S.; Stallknecht, D. E.; Poulson, R. L.; Saliki, J. T.; Tompkins, S. M.; Padykula, I.; Siepker, C.; Howerth, E. W.; Todd, M.; Stanton, J. B.

10.1101/2019.12.16.875872 — pathology — Posted on 2019-12-16

1448 Topographic mapping as a basic principle of functional organization for visual and prefrontal functional connectivity

O'Rawe, J. F.; Leung, H.-C.

10.1101/549345 — neuroscience — Posted on 2019-12-16

1449 Dissociable roles of cortical excitation-inhibition balance during patch-leaving versus value-guided decisions

Kaiser, L. F.; Gruendler, T. O. J.; Speck, O.; Luettgau, L.; Jocham, G.

10.1101/2019.12.15.877019 — neuroscience — Posted on 2019-12-16

1450 Co-ordinated regulation of cell survival and cell cycle pathways by DDR2-dependent SRF transcription factor in cardiac fibroblasts

Titus, A. S.; V, H.; Kailasam, S.

10.1101/857037 — molecular biology — Posted on 2019-12-16

1451 Mitochondrial phylogeography reveals high diversity and unique divergent lineage in Indian Dugongs (Dugong dugon)

Srinivas, Y.; Pande, A.; Gole, S.; Jothi, P. P. V. R.; Magesh, M.; Pathan, S.; Dudhat, S.; Shekar, R.; Kukadia, D.; Johnson, J. A.; Mondol, S.; Sivakumar, K.

10.1101/2019.12.16.877415 — molecular biology — Posted on 2019-12-16

1452 A Central Role for Canonical PRC1 in Shaping the 3D Nuclear Landscape

Boyle, S.; Flyamer, I. M.; Williamson, I.; Sengupta, D.; Bickmore, W. A.; Illingworth, R. S.

10.1101/2019.12.15.876771 — molecular biology — Posted on 2019-12-16

1453 Mechanism of in vivo activation of the MutLγ-Exo1 complex for meiotic crossover formation

Sanchez, A.; Adam, C.; Rauh, F.; Duroc, Y.; Ranjha, L.; Lombard, B.; Mu, X.; Loew, D.; Keeney, S.; Cejka, P.; Guerois, R.; Klein, F.; Charbonnier, J.-B.; Borde, V.

10.1101/2019.12.16.876623 — molecular biology — Posted on 2019-12-16

1454 Biofilm structure promotes coexistence of phage-resistant and phage-susceptible bacteria

Simmons, M.; Bond, M. C.; Koskella, B.; Drescher, K.; Bucci, V.; Nadell, C. D.

10.1101/552265 — microbiology — Posted on 2019-12-16

1455 Comprehensive genome data analysis establishes a triple whammy of carbapenemases, ICEs and multiple clinically-relevant bacteria

Botelho, J.; Mourao, J.; Roberts, A. P.; Peixe, L. V.

10.1101/678748 — microbiology — Posted on 2019-12-16

1456 Homozygous STAT2 gain-of-function mutation by loss of USP18 activity in a patient with type I interferonopathy

Gruber, C. N.; Martin-Fernandez, M.; Ailal, F.; Qiu, X.; Taft, J.; Altman, J.; Rosain, J.; Buta, S.; Bousfiha, A.; Casanova, J.-L.; Bustamante, J.; Bogunovic, D.

10.1101/2019.12.12.874123 — immunology — Posted on 2019-12-16

1457 Don't Dismiss Logistic Regression: The Case for Sensible Extraction of Interactions in the Era of Machine Learning

Levy, J. J.; O'Malley, J.

10.1101/2019.12.15.877134 — bioinformatics — Posted on 2019-12-16

1458 A spectral jamming avoidance response does not help bats deal with jamming

Mazar, O.; Yovel, Y.

10.1101/2019.12.16.876086 — animal behavior and cognition — Posted on 2019-12-16

1459 Evidence for unfamiliar kin recognition in vampire bats

Ripperger, S. P.; Page, R. A.; Mayer, F.; Carter, G. G.

10.1101/2019.12.16.874057 — animal behavior and cognition — Posted on 2019-12-16

1460 How community adaptation affects biodiversity-ecosystem functioning relationships

Aubree, F.; David, P.; Jarne, P.; Loreau, M.; Mouquet, N.; Calcagno, V.

10.1101/867820 — evolutionary biology — Posted on 2019-12-16

1461 In vitro pancreatic islet cluster expansion facilitated by hormones and chemicals

Lin, J.-Y.; Cheng, J.; Du, Y.-Q.; Pan, W.; Zhang, Z.; Wang, J.; Yang, Z.; Yang, F.; Xu, Y.-F.; Lin, H.; An, W.-T.; Wang, J.; An, J.; Chai, R.-J.; Hu, H.-L.; Sun, J.; Yu, X.

10.1101/2019.12.16.873596 — cell biology — Posted on 2019-12-16

1462 Metabolic modelling of CAM cycling, CAM idling and the C3-CAM continuum

Tay, I. Y. Y.; Odang, K. B.; Cheung, C. Y. M.

10.1101/2019.12.16.877621 — biochemistry — Posted on 2019-12-16

1463 Subunit joining exposes nascent pre-40S rRNA for processing and quality control

Rai, J.; Parker, M. D.; Huang, H.; Choi, S.; Ghalei, H.; Johnson, M. C.; Karbstein, K.; Stroupe, M. E.

10.1101/617910 — biochemistry — Posted on 2019-12-16

1464 Estimating the effective sample size in association studies of quantitative traits

Ziyatdinov, A.; Kim, J.; Prokopenko, D.; Prive, F.; Laporte, F.; Loh, P.-R.; Kraft, P.; Aschard, H.

10.1101/2019.12.15.877217 — genetics — Posted on 2019-12-16

1465 Clair: Exploring the limit of using a deep neural network on pileup data for germline variant calling

Luo, R.; Wong, C.-L.; Wong, Y.-S.; Tang, C.-I.; Liu, C.-M.; Leung, H. C. M.; Lam, T.-W.

10.1101/865782 — bioinformatics — Posted on 2019-12-16

1466 P38α Regulates Expression of DUX4 in Facioscapulohumeral Muscular Dystrophy

Rojas, L. A.; Valentine, E.; Accorsi, A.; Maglio, J.; Shen, N.; Robertson, A.; Kazmirski, S.; Rahl, P.; Tawil, R.; Cadavid, D.; Thompson, L. A.; Ronco, L.; Chang, A. N.; Cacace, A. M.; Wallace, O.

10.1101/700195 — developmental biology — Posted on 2019-12-16

1467 Characterization of the adaptation to visuomotor rotations in the muscle synergies space

Severini, G.; Zych, M.

10.1101/2019.12.12.873802 — bioengineering — Posted on 2019-12-16

1468 Visualising nascent chain dynamics at the ribosome exit tunnel by cryo-electron microscopy

Javed, A.; Wlodarski, T.; Cassaignau, A. M. E.; Cabrita, L.; Christodoulou, J.; Orlova, E. V.

10.1101/722611 — biophysics — Posted on 2019-12-16

1469 SAXS Curves of Detergent Micelles: Effects of Asymmetry, Shape Fluctuations, Disorder, and Atomic Details

Ivanovic, M. T.; Hermann, M. R.; Wojcik, M.; Perez, J.; Hub, J. S.

10.1101/815266 — biophysics — Posted on 2019-12-16

1470 Boosting Brain Signal Variability Underlies Liberal Shifts in Decision Bias

Kloosterman, N. A.; Kosciessa, J. Q.; Lindenberger, U.; Fahrenfort, J. J.; Garrett, D. D.

10.1101/834614 — neuroscience — Posted on 2019-12-16

1471 L-type voltage-gated calcium channel modulators inhibit glutamate-induced morphology in astrocytoma cells

Tabatabaee, M. S.; Menard, F.

10.1101/2019.12.15.875799 — neuroscience — Posted on 2019-12-16

1472 Noncoding de novo mutations contribute to autism spectrum disorder via chromatin interactions

Kim, I. B.; Lee, T.; Lee, J.; Kim, J.; Lee, H.; Kim, W. K.; Ju, Y. S.; Cho, Y.; Yu, S. J.; Kim, S. A.; Oh, M.; Kwak, T. H.; Kim, E.; Choi, J. K.; Yoo, H. J.; Lee, J. H.

10.1101/2019.12.15.877324 — neuroscience — Posted on 2019-12-16

1473 Adaptive introgression across semipermeable species boundaries between local Helicoverpa zea and invasive Helicoverpa armigera moths

Valencia-Montoya, W. A.; Elfekih, S.; North, H. L.; Meier, J. I.; Warren, I. A.; Tay, W. T.; Gordon, K. H. J.; Specht, A.; Paula-Moraes, S. V.; Rane, R.; Walsh, T. K.; Jiggins, C. D.

10.1101/2019.12.15.877225 — evolutionary biology — Posted on 2019-12-16

1474 Beyond target-decoy competition: stable validation of peptide and protein identifications in mass spectrometry-based discovery proteomics

Coute, Y.; Bruley, C.; Burger, T.

10.1101/765057 — bioinformatics — Posted on 2019-12-16

1475 SurfaceGenie: A web-based application for prioritizing cell-type specific marker candidates

Waas, M.; Terai Snarrenberg, S.; Littrell, J.; Jones Lipinski, R.; Hansen, P.; Corbett, J.; Gundry, R.

10.1101/575969 — systems biology — Posted on 2019-12-16

1476 Diverse genetic origins of medieval steppe nomad conquerors

Mikheyev, A.; Qiu, L.; Zarubin, A.; Moshkov, N.; Orlov, Y.; Chartier, D.; Faleeva, T.; Kornienko, I.; Klyuchnikov, V.; Batieva, E.; Tatarinova, T. V.

10.1101/2019.12.15.876912 — paleontology — Posted on 2019-12-16

1477 Microbial degradation of plastic in aqueous solutions demonstrated by CO2 evolution and quantification.

Rose, R. S.; Richardson, K. H.; Latvanen, E. J.; Hanson, C. A.; Resmini, M.; Sanders, I. A.

10.1101/719476 — microbiology — Posted on 2019-12-16

1478 Culex saltanensis and Culex interfor (Diptera: Culicidae) are susceptible and competent to transmit St. Louis encephalitis virus (Flavivirus: Flaviviridae) in central Argentina.

Beranek, M.; Quaglia, A.; Peralta, G.; Flores, F.; Stein, M.; Diaz, A.; Almiron, W.; Contigiani, M.

10.1101/722579 — microbiology — Posted on 2019-12-16

1479 Dscam homophilic specificity is generated by high order cis-multimers coupled with trans self-binding of variable Ig1 in Chelicerata

Zhou, F.; Cao, G.; Dai, S.; Li, G.; Li, H.; Ding, Z.; Hou, S.; Xu, B.; You, W.; Shi, F.; Yang, X.; Yongfeng, J.

10.1101/2019.12.15.877159 — biochemistry — Posted on 2019-12-16

1480 Control of adaptive action selection by secondary motor cortex during flexible visual categorization

Wang, T.-Y.; Liu, J.; Yao, H.

10.1101/2019.12.16.877381 — neuroscience — Posted on 2019-12-16

1481 DiADeM: differential analysis via dependency modelling of chromatin interactions with robust generalized linear models

Zaborowski, R.; Wilczynski, B.

10.1101/654699 — bioinformatics — Posted on 2019-12-16

1482 Increasing pulse energy of 5Hz rTMS improves its efficacy in inducing excitatory aftereffects.

Halawa, I.; Reichert, K.; Anil, S.; Sommer, M.; Paulus, W.

10.1101/652578 — neuroscience — Posted on 2019-12-16

1483 Fast sequence-based microsatellite genotyping development workflow.

Lepais, O.; Chancerel, E.; Boury, C.; Salin, F.; Manicki, A.; Taillebois, L.; Dutech, C.; Aissi, A.; Bacles, C. F. E.; Daverat, F.; Launey, S.; Guichoux, E.

10.1101/649772 — genetics — Posted on 2019-12-16

1484 Physiological and morphological correlates of extreme acid tolerance in larvae of the acidophilic amphibian Litoria cooloolensis (Anura: Pelodryadidae)

Meyer, E. A.; Franklin, C. E.; Cramp, R. L.

10.1101/2019.12.15.872259 — zoology — Posted on 2019-12-16

1485 Is N-Hacking Ever OK? A Simulation-based study

Reinagel, P.

10.1101/2019.12.12.868489 — scientific communication and education — Posted on 2019-12-16

1486 Statistical Pattern Recognition Reveals Shared Neural Signatures for Displaying and Recognizing Specific Facial Expressions

Volynets, S.; Saarimaki, H.; Nummenmaa, L.; Smirnov, D.

10.1101/2019.12.15.873737 — neuroscience — Posted on 2019-12-16

1487 Simple spectral transformations capture the contribution of peripheral processing to cortical responses to natural sounds

Rahman, M.; Willmore, B. D. B.; King, A. J.; Harper, N. S.

10.1101/2019.12.15.877142 — neuroscience — Posted on 2019-12-16

1488 Nwd1 regulates neuronal differentiation and migration through purinosome formation in the developing cerebral cortex

Yamada, S.; Sato, A.; Sakakibara, S.-i.

10.1101/2019.12.15.877340 — neuroscience — Posted on 2019-12-16

1489 An open-source multiple-bioreactor system for replicable gas-fermentation experiments: Nitrate feed results in stochastic inhibition events, but improves ethanol production of Clostridium ljungdahlii with CO2 and H2

Klask, C.-M.; Kliem-Kuster, N.; Molitor, B.; Angenent, L. T.

10.1101/2019.12.15.877050 — microbiology — Posted on 2019-12-16

1490 High-throughput screening of the ReFRAME library identifies potential drug repurposing candidates for Trypanosoma cruzi

Bernatchez, J. A.; Chen, E.; Hull, M. V.; McNamara, C. W.; McKerrow, J. H.; Siqueira-Neto, J. L.

10.1101/2019.12.11.873711 — microbiology — Posted on 2019-12-16

1491 On the Order of Gene Distribution on Chromosomes Across the Animal Kingdom

Toor, A. A.; Toor, A. A.

10.1101/2019.12.15.877167 — genomics — Posted on 2019-12-16

1492 Notch ligand Dll4 impairs cell recruitment into aortic clusters and limits hematopoietic stem cells

Bigas, A.

10.1101/2019.12.16.877407 — developmental biology — Posted on 2019-12-16

1493 Structural studies of thyroid peroxidase show the monomer interacting with autoantibodies in thyroid autoimmune disease

Williams, D. E.; Le, S. N.; Hoke, D. E.; Chandler, P. G.; Gora, M.; Godlewska, M.; Banga, J. P.; Buckle, A. M.

10.1101/2019.12.15.876789 — biochemistry — Posted on 2019-12-16

1494 Delineating the Organization of Projection Neuron Subsets with Multi-fluorescent Rabies Virus Tracing Tool

Li, L.; tang, y.; Sun, L.; Yu, J.; Gong, H.; Webber, H. C.; Zhang, X.; Hu, Z.; Li, X.; Rahman, K.; Fu, Z.; Dai, J.; Cao, G.

10.1101/2019.12.16.877258 — neuroscience — Posted on 2019-12-16

1495 Limited evidence for selection at the FADS locus in Native American populations

Mathieson, I.

10.1101/2019.12.11.873356 — evolutionary biology — Posted on 2019-12-16

1496 Inventive nesting behaviour in the keyhole wasp Pachodynerus nasidens Latreille (Hymenoptera: Vespidae) in Australia, and the risk to aviation safety

House, A. P. N.; Ring, J. G.; Shaw, P. P.

10.1101/2019.12.15.877274 — ecology — Posted on 2019-12-16

1497 Non-uniform refinement: Adaptive regularization improves single particle cryo-EM reconstruction

Punjani, A.; Zhang, H.; Fleet, D. J.

10.1101/2019.12.15.877092 — biophysics — Posted on 2019-12-16

1498 Deep Docking - a Deep Learning Approach for Virtual Screening of Big Chemical Datasets

Gentile, F.; Agrawal, V.; Hsing, M.; Ban, F.; Norinder, U.; Gleave, M. E.; Cherkasov, A.

10.1101/2019.12.15.877316 — bioinformatics — Posted on 2019-12-16

1499 Microbiome Determinants and Physiological Effects of the Benzoate-Hippurate Microbial-Host Co-Metabolic Pathway

Brial, F.; Chilloux, J.; Nielsen, T.; Vieira Silva, S.; Falony, G.; Hoyles, L.; Neves, A. L.; Rodriguez Martinez, A.; Mouawad, G. I.; Pons, N.; Forslund, S. K.; Le Chatelier, E.; Le Lay, A.; Nicholson, J. K.; Hansen, T.; Clement, K.; Bork, P.; Ehrlich, D.; Raes, J.; Pedersen, O.; Gauguier, D.; Dumas, M. E.

10.1101/2019.12.15.876672 — systems biology — Posted on 2019-12-16

1500 PERSIST: A programmable RNA regulation platform using CRISPR endoRNases

DiAndreth, B.; Wauford, N.; Hu, E.; Palacios, S.; Weiss, R.

10.1101/2019.12.15.867150 — synthetic biology — Posted on 2019-12-16

1501 Loss of Tsc1 from striatal direct pathway neurons impairs endocannabinoid-LTD and enhances motor routine learning

Benthall, K. N.; Cording, K. R.; Agopyan-Miu, A. H. C. W.; Chen, E. Y.; Bateup, H. S.

10.1101/2019.12.15.877126 — neuroscience — Posted on 2019-12-16

1502 RhoGAP RGA-8 supports morphogenesis in C. elegans by polarizing epithelia through CDC-42

Raduwan, H.; Sasidharan, S.; Cordova Burgos, L.; Wallace, A.; Soto, M. C.

10.1101/2019.12.15.877332 — developmental biology — Posted on 2019-12-16

1503 Science communication in online media: influence of press releases on coverage of genetics and CRISPR

Grochala, R.

10.1101/2019.12.13.875278 — scientific communication and education — Posted on 2019-12-16

1504 Gene Expression Correlates of the Cortical Network Underlying Sentence Processing

Kong, X.-Z.; Tzourio-Mazoyer, N.; Joliot, M.; Fedorenko, E.; Liu, J.; Fisher, S. E.; Francks, C.

10.1101/439984 — neuroscience — Posted on 2019-12-16

1505 A CRISPR screen identifies UFMylation and TRAMP-like complexes required for hepatitis A virus infection

Puschnik, A. S.; Kulsuptrakul, J.; Wang, R.; Meyers, N. L.; Ott, M.

10.1101/2019.12.15.877100 — microbiology — Posted on 2019-12-16

1506 Nucleosides drive histiocytosis in SLC29A3 disorders by activating TLR7

Shibata, T.; Taoka, M.; Saitoh, S.-I.; Yamauchi, Y.; Motoi, Y.; Komine, M.; Fujita, E.; Sato, R.; Sagara, H.; Ichinohe, T.; Kawazoe, M.; Kato, C.; Furusho, K.; Murakami, Y.; Fukui, R.; Ohtsuki, M.; Ohto, U.; Shimizu, T.; Yoshida, N.; Isobe, T.; MIYAKE, K.

10.1101/2019.12.16.877357 — immunology — Posted on 2019-12-16

1507 Proteomics Analysis of Differential Expression of Lung Proteins in Response to Highly Pathogenic Avian Influenza Virus Infection in Chicken

Vijayakumar, P.; Raut, A. A.; Chingtham, S.; Murugkar, H. V.; Kulkarni, D. D.; Singh, V. P.; Mishra, A.

10.1101/2019.12.16.877456 — immunology — Posted on 2019-12-16

1508 Genetic Identification of Cell Types Underlying Brain Complex Traits Yields Novel Insights Into the Etiology of Parkinson's Disease

Bryois, J.; Skene, N. G.; Folkmann Hansen, T.; Kogelman, L. J. A.; Watson, H. J.; Liu, Z.; Eating Disorders Working Group of the Psychiatric, ; International Headache Genetics Consortium, ; The 23andMe Research Team, ; Brueggeman, L.; Breen, G.; Bulik, C. M.; Arenas, E.; Hjerling-Leffler, J.; Sullivan, P. F.

10.1101/528463 — genomics — Posted on 2019-12-16

1509 Insulin-stimulated glucose uptake partly relies on p21-activated kinase (PAK)-2, but not PAK1, in mouse skeletal muscle

Moller, L. L. V.; Jaurji, M.; Kjobsted, R.; Joseph, G. A.; Madsen, A. B.; Knudsen, J. R.; Lundsgaard, A.-M.; Andersen, N. R.; Schjerling, P.; Jensen, T. E.; Krauss, R. S.; Richter, E. A.; Sylow, L.

10.1101/543736 — cell biology — Posted on 2019-12-16

1510 Stone Alkaline Water Induces Apoptosis of Prostate Cancer Cells and Inhibits Tumor Cell Induced Angiogenesis In Vitro

Appak-Baskoy, S.; Kulcanay-Sahin, I.; Teksoy, O.; Cengiz, M.; Deveci Ozkan, A.; Guney Eskiler, G.; Bilici, N.; Oztopcu-Vatan, P.; Altuner, Y.; Ayhanci, A.

10.1101/2019.12.15.877233 — cancer biology — Posted on 2019-12-16

1511 Word stress representations are language specific: evidence from event-related brain potentials

Honbolygo, F.; Kobor, A.; German, B.; Csepe, V.

10.1101/442129 — neuroscience — Posted on 2019-12-16

1512 The genomic view of diversification

Marin, J.; Achaz, G.; Crombach, A.; Lambert, A.

10.1101/413427 — evolutionary biology — Posted on 2019-12-16

1513 EffectorK, a comprehensive resource to mine for pathogen effector targets in the Arabidopsis proteome

Gonzalez-Fuente, M.; Carrere, S.; Monachello, D.; Marsella, B. G.; Cazale, A.-C.; Zischek, C.; Mitra, R. M.; Reze, N.; Cottret, L.; Mukhtar, M. S.; Lurin, C.; Noel, L. D.; Peeters, N.

10.1101/2019.12.16.878074 — plant biology — Posted on 2019-12-16

1514 Effect of EBV-transformation on Oxidative Phosphorylation Physiology in Human Cell lines

Crawford, D. L.; Weinstein, R. N.

10.1101/2019.12.16.878025 — evolutionary biology — Posted on 2019-12-16

1515 Gene regulatory networks associated with lateral root and nodule development in soybean

Smita, S.; Kiehne, J.; Adhikari, S.; Zeng, E.; Ma, Q.; Subramanian, S.

10.1101/2019.12.15.876995 — plant biology — Posted on 2019-12-16

1516 KDM5 histone-demethylases contribute to replication stress response and tolerance.

Vandromme, M.; Gaillard, S.; Charasson, V.; Ribeyre, C.; Salifou, K.; Pillaire, M.-J.; Hoffmann, J.-S.; Constantinou, A.; Trouche, D.

10.1101/2019.12.16.877399 — cancer biology — Posted on 2019-12-16

1517 Sox8 and Sox9 act redundantly for ovarian-to-testicular fate reprogramming in the absence of Rspo1 in mouse sex reversal

Chaboissier, M.-C.; Richardson, N.; Gillot, I.; Gregoire, E. P.; Youssef, S. A.; de Rooij, D.; de Bruin, A.; De Cian, M.-C.

10.1101/2019.12.13.875443 — developmental biology — Posted on 2019-12-16

1518 The proteomic inventory reveals the chloroplast ribosome as nexus within a diverse protein network

Willmund, F.; Westrich, L. D.; Gotsmann, V. L.; Herkt, C.; Ries, F.; Kazek, T.; Trösch, R.; Ramundo, S.; Nickelsen, J.; Armbruster, L.; Wirtz, M.; Storchova, Z.; Raeschle, M.

10.1101/2019.12.12.874503 — biochemistry — Posted on 2019-12-16

1519 Compartment and cell type-{-}specific hypoxia responses in the developing Drosophila brain

Baccino-Calace, M.; Prieto, D.; Cantera, R.; Egger, B.

10.1101/2019.12.12.874404 — developmental biology — Posted on 2019-12-16

1520 Segregation of Familial Risk of Obesity in NHANES Cohort Supports a Major Role for Large Genetic Effects in the Current Obesity Epidemic

Jenkins, A. B.; Batterham, M.; Campbell, L. V.

10.1101/749606 — genetics — Posted on 2019-12-16

1521 Genome-wide changes in genetic diversity in a population of Myotis lucifugus affected by white-nose syndrome

Lilley, T.; Wilson, I.; Field, K. A.; Reeder, D. M.; Turner, G. G.; Kurta, A.; Blomberg, A. S.; Hoff, S.; Herzog, C.; Paterson, S.

10.1101/764647 — evolutionary biology — Posted on 2019-12-16

1522 Cotranslational folding cooperativity of contiguous domains of α-spectrin

Kemp, G.; Nilsson, O. B.; Tian, P.; Best, R. B.; Von Heijne, G.

10.1101/653360 — biochemistry — Posted on 2019-12-16

1523 Transcription-factor binding to replicated DNA

Bar-Ziv, R.; Brodsky, S.; Chapal, M.; Barkai, N.

10.1101/2019.12.15.877035 — systems biology — Posted on 2019-12-15

1524 FK506-binding protein 13 expression is upregulated in interstitial lung disease and correlated with clinical severity: a potentially protective role.

Tat, V.; Ayaub, E. A.; Ayoub, A.; Vierhout, M.; Naiel, S.; Padwal, M.; Abed, S.; Mekhael, O.; Tandon, K.; Revill, S. D.; Yousof, T.; Bellaye, P.-S.; Kolb, P.; Dvorkin-Gheva, A.; Naqvi, A.; Cutz, J.-C.; Hambly, N.; Kato, J.; Vaughan, M.; Moss, J.; Kolb, M.; Ask, K.

10.1101/2019.12.15.858340 — pathology — Posted on 2019-12-15

1525 Nonparametric Anomaly Detection on Time Series of Graphs

Ofori-Boateng, D.; Gel, Y.; Cribben, I.

10.1101/2019.12.15.876730 — neuroscience — Posted on 2019-12-15

1526 Hemagglutinin of Influenza A, but not of Influenza B and C viruses is acylated by ZDHHC2, 8, 15 and 20

Gadalla, M. R.; Abrami, L.; van der Goot, F. G.; Veit, M.

10.1101/2019.12.15.877001 — microbiology — Posted on 2019-12-15

1527 MAVS regulates the quality of the antibody response to West-Nile Virus

O'Ketch, M.; Larson, C.; Williams, S.; Uhrlaub, J. L.; Wong, R.; Deshpande, N. R.; Schenten, D.

10.1101/2019.12.15.875906 — immunology — Posted on 2019-12-15

1528 Reward produces learning of a consciously inaccessible feature

Dong, X.; Zhang, M.; Dong, B.; Jiang, Y.; Bao, M.

10.1101/2019.12.13.876243 — neuroscience — Posted on 2019-12-15

1529 Susceptibility to auditory closed-loop stimulation of sleep slow oscillations changes with age

Schneider, J.; Lewis, P. A.; Koester, D.; Born, J.; Ngo, H.-V. V.

10.1101/2019.12.15.876847 — neuroscience — Posted on 2019-12-15

1530 Global broadcasting of local fractal fluctuations in a bodywide distributed system supports perception via effortful touch

Mangalam, M.; Carver, N. S.; Kelty-Stephen, D. G.

10.1101/2019.12.15.876961 — neuroscience — Posted on 2019-12-15

1531 Anti-inflammatory treatment with FTY720 starting after onset of symptoms reverses synaptic and memory deficits in an AD mouse model

Kartalou, G.-I.; Pereira, A. R. S.; Endres, T.; Lesnikova, A.; Casarotto, P.; Pousinha, P.; Delanoe, K.; Edelmann, E.; Castren, E.; Gottmann, K.; Marie, H.; Lessmann, V.

10.1101/2019.12.15.868026 — neuroscience — Posted on 2019-12-15

1532 Stochastic dynamics of extra-chromosomal DNA

Pichugin, Y.; Huang, W.; Werner, B.

10.1101/2019.12.15.876714 — cancer biology — Posted on 2019-12-15

1533 ASTRAL-Pro: quartet-based species tree inference despite paralogy

Zhang, C.; Scornavacca, C.; Molloy, E.; Mirarab, S.

10.1101/2019.12.12.874727 — bioinformatics — Posted on 2019-12-15

1534 OLGenie: Estimating Natural Selection to Predict Functional Overlapping Genes

Nelson, C. W.; Ardern, Z.; Wei, X.

10.1101/2019.12.14.876607 — evolutionary biology — Posted on 2019-12-15

1535 Folding heterogeneity in the essential human telomerase RNA three-way junction

Palka, C.; Forino, N. M.; Henstchel, J.; Das, R.; Stone, M. D.

10.1101/2019.12.14.876565 — biochemistry — Posted on 2019-12-15

1536 Genetic characterization of African swine fever virus in Romania during 2018-2019 outbreak

Petrovan, V.; Turcitu, M.; Matei, L.; Constantinescu, V.; Zaulet, M.

10.1101/2019.12.15.876938 — microbiology — Posted on 2019-12-15

1537 Defining the relative and combined contribution of CTCF and CTCFL to genomic regulation

Nishana, M.; Rodriguez-Hernaez, J.; Ha, C.; Chio, E.; Nora, E. P.; Badri, S. B.; Kloetgen, A.; Bruneau, B.; Tsirigos, A.; Skok, J. A.

10.1101/2019.12.14.874560 — genomics — Posted on 2019-12-15

1538 Properties and effect of Ittar in mice behavior and neurological functions

Al-Asmari, A. R.; Kunnathodi, F.; Anvarbatcha, R.; Tanwir Athar, M.; Sigmani, D.; Idris, M. M.

10.1101/2019.12.15.876581 — neuroscience — Posted on 2019-12-15

1539 A Central Role for Canonical PRC1 in Shaping the 3D Nuclear Landscape

Boyle, S.; Flyamer, I. M.; Williamson, W. I.; Sengupta, D.; Bickmore, W. A.; Illingworth, R. S.

10.1101/2019.12.15.876771 — molecular biology — Posted on 2019-12-15

1540 Medical relevance of common protein-altering variants in GPCR genes across 337,205 individuals in the UK Biobank study

DeBoever, C.; Venkatakrishnan, A. J.; Paggi, J. M.; Heydenreich, F. M.; Laurin, S.-A.; Masureel, M.; Tanigawa, Y.; Venkataraman, G.; Bouvier, M.; Dror, R.; Rivas, M. A.

10.1101/2019.12.13.876250 — genetics — Posted on 2019-12-15

1541 Towards a Chimeric Vaccine against Multiple Isolates of Mycobacteroides - An Integrative Approach

Satyam, R.; Bhardwaj, T.; Jha, N. K.

10.1101/2019.12.15.869081 — bioinformatics — Posted on 2019-12-15

1542 Individual Learning Phenotypes Drive Collective Cognition

Cook, C. N.; Lemanski, N. J.; Mosqueiro, T.; Ozturk, C.; Gadau, J.; Pinter-Wollman, N.; Smith, B. H.

10.1101/761676 — animal behavior and cognition — Posted on 2019-12-15

1543 Keystone genes of mammalian tooth patterning and quantification of their expression

Hallikas, O.; Das Roy, R.; Christensen, M. M.; Renvoise, E.; Sulic, A.-M.; Jernvall, J.

10.1101/869065 — developmental biology — Posted on 2019-12-15

1544 Induced aneuploidy disrupts MCF10A acini formation and CCND1 expression

Waschow, M.; Wang, Q.; Saary, P.; Klein, C.; Aschenbrenner, S.; Jechow, K.; Maier, L.; Tirier, S.; Schoell, B.; Chudoba, I.; Dietz, C.; Dreidax, D.; Jauch, A.; Sprick, M.; Herrmann, C.; Eils, R.; Conrad, C.

10.1101/2019.12.15.876763 — cancer biology — Posted on 2019-12-15

1545 Degree and site of chromosomal instability define its oncogenic potential

Hoevenaar, W.; Janssen, A.; Quirindongo, A.; Ma, H.; Klaasen, S.; Teixeira, A.; Offerhaus, J.; Medema, R.; Kops, G.; Jelluma, N.

10.1101/638460 — cancer biology — Posted on 2019-12-15

1546 Two distinct mechanisms of small molecule inhibition of LpxA acyltransferase essential for lipopolysaccharide biosynthesis

Han, W.; Ma, X.; Balibar, C. J.; Baxter Rath, C. M.; Benton, B.; Bermingham, A.; Casey, F.; Chi-Leon, B.; Cho, M.-K.; Frank, A. O.; Frommlet, A.; Ho, C.-M.; Lee, P. S.; Li, M.; Lingel, A.; Ma, S.; Merritt, H.; Ornelas, E.; de Pascale, G.; Prathapam, R.; Prosen, K. R.; Rasper, D.; Ruzin, A.; Sawyer, W.; Shaul, J.; Shen, X.; Shia, S.; Steffek, M.; Subramanian, S.; Vo, J.; Wang, F.; Wartchow, C.; Uehara, T.

10.1101/2019.12.14.850305 — biochemistry — Posted on 2019-12-15

1547 In vivo studies of glucagon secretion by human islets transplanted in mice

Tellez, K.; Hang, Y.; Gu, X.; Stein, R. W.; Kim, S. K.

10.1101/2019.12.15.876920 — physiology — Posted on 2019-12-15

1548 Preclinical zebrafish model for organophosphorus intoxication: neuronal hyperexcitation, behavioral abnormalities and subsequent brain damages

Brenet, A.; Somkhit, J.; Hassan-Abdi, R.; Yanicostas, C.; Igert, A.; Saurat, D.; Taudon, N.; Loyant, R.; Porceddu, P.; Dal-Bo, G.; Nachon, F.; Dupuis, N.; Soussi-Yanicostas, N.

10.1101/2019.12.15.876649 — neuroscience — Posted on 2019-12-15

1549 Potential Neurocognitive Biomarkers for Post Traumatic Stress Disorder (PTSD) Severity in Recent Trauma Survivors

Ben-Zion, Z.; Zeevi, Y.; Keynan, N. J.; Admon, R.; Kozlovski, T.; Sharon, H.; Halpern, P.; Liberzon, I.; Shalev, A.; Benjamini, Y.; Hendler, T.

10.1101/721068 — neuroscience — Posted on 2019-12-15

1550 Cell-specific exon methylation and CTCF binding in neurons regulates calcium ion channel splicing and function

Lopez Soto, E. J.; Lipscombe, D.

10.1101/2019.12.15.876185 — neuroscience — Posted on 2019-12-15

1551 On anammox activity at low temperature: effect of ladderane composition, process conditions and dominant anammox population

Kouba, V.; Hurkova, K.; Navratilova, K.; Vejmelkova, D.; Benakova, A.; Laureni, M.; Vodickova, P.; Podzimek, T.; Lipovova, P.; van Niftrik, L.; Hajslova, J.; van Loosdrecht, M. C. M.; Weissbrodt, D. G.; Bartacek, J.

10.1101/2019.12.15.873869 — microbiology — Posted on 2019-12-15

1552 EBV latent membrane protein 1 induces lipogenesis and confers sensitivity to inhibition of fatty acid synthase in B cells.

Hulse, M.; Johnson, S.; Boyle, S.; Caruso, L. B.; Schwell, V.; Tempera, I.

10.1101/2019.12.15.876821 — microbiology — Posted on 2019-12-15

1553 Separating overlapping bat calls with a bi-directional long short-term memory network

Zhang, K.; Liu, T.; Song, S.; Zhao, X.; Sun, S.; Metzner, W.; Feng, J.; Liu, Y.

10.1101/2019.12.15.876656 — ecology — Posted on 2019-12-15

1554 Simulation and Analysis of Animal Movement Paths using Numerus Model Builder

Getz, W.; Vissat, L. L.; Salter, R.

10.1101/2019.12.15.876987 — ecology — Posted on 2019-12-15

1555 Inducible transgene expression in PDX models in vivo identifies KLF4 as therapeutic target for B-ALL

Liu, W.-H.; Mrozek-Gorska, P.; Herold, T.; Schwarzkopf, L.; Pich, D.; Völse, K.; Wirth, A.-K.; Melo-Narvaez, M. C.; Carlet, M.; Hammerschmidt, W.; Jeremias, I.

10.1101/737726 — cancer biology — Posted on 2019-12-15

1556 Stretchable Composite Acoustic Transducer for Wearable Monitoring of Vital Signs

Cotur, Y.; Kasimatis, M.; Kaisti, M.; Olenik, S.; Georgiou, C.; Guder, F.

10.1101/2019.12.14.876409 — bioengineering — Posted on 2019-12-15

1557 Optical activation of TrkB receptors

Huang, P.; Liu, A.; Song, Y.; Hope, J. M.; Cui, B.; Duan, L.

10.1101/2019.12.15.876722 — synthetic biology — Posted on 2019-12-15

1558 Ontario Neurodegenerative Disease Research Initiative (ONDRI): Structural MRI methods & outcome measures

10.1101/2019.12.13.875823 — neuroscience — Posted on 2019-12-15

1559 Tools and Resources: Remote, automated and MRI-compatible administration of interoceptive inspiratory resistive loading

Rieger, S. W.; Stephan, K. E.; Faull, O. K.

10.1101/2019.12.09.869511 — neuroscience — Posted on 2019-12-15

1560 Distribution and strength of interlaminar synaptic connectivity in mouse primary visual cortex revealed by two-photon optogenetic stimulation

Hage, T. A.; Bosma-Moody, A.; Baker, C. A.; Kratz, M. B.; Campagnola, L.; Jarsky, T.; Zeng, H.; Murphy, G. J.

10.1101/2019.12.13.876128 — neuroscience — Posted on 2019-12-15

1561 Serotonin, norepinephrine and acetylcholine differentially affect astrocytic potassium clearance to modulate somatosensory signaling in male mice

Wotton, C. A.; Cross, C. D.; Bekar, L. K.

10.1101/2019.12.14.876458 — neuroscience — Posted on 2019-12-15

1562 Molecular layer interneurons in the cerebellum encode for valence in associative learning

Ma, M.; Futia, G. L.; Ozbay, B. N.; Gibson, E. A.; Restrepo, D.

10.1101/2019.12.14.876201 — neuroscience — Posted on 2019-12-15

1563 Distinct transcriptomic cell types and neural circuits of the subiculum and prosubiculum along the dorsal-ventral axis

Ding, S.-L.; Yao, Z.; Hirokawa, K. E.; Nguyen, T. N.; Graybuck, L. T.; Fong, O.; Bohn, P.; Ngo, K.; Smith, K. A.; Koch, C.; Phillips, J. W.; Lein, E. S.; Harris, J. A.; Tasic, B.; Zeng, H.

10.1101/2019.12.14.876516 — neuroscience — Posted on 2019-12-15

1564 Complexity of frequency receptive fields predicts tonotopic variability across species

Gaucher, Q.; Panniello, M.; Ivanov, A. Z.; Dahmen, J. C.; King, A. J.; Walker, K. M. M.

10.1101/2019.12.15.876748 — neuroscience — Posted on 2019-12-15

1565 Gene drive and resilience through renewal with next generation Cleave and Rescue selfish genetic elements

Oberhofer, G.; Ivy, T.; Hay, B. A.

10.1101/2019.12.13.876169 — genetics — Posted on 2019-12-15

1566 The 9aaTAD activation domains in the four Yamanaka Oct4, Sox2, Myc, and Klf4 transcription factors essential during the stem cell development

Piskacek, M.; Jendruchova, K.; Rezacova, M.; Havelka, M.; Gasparik, N.; Hofrova, A.; Knight, A.

10.1101/2019.12.15.876706 — genetics — Posted on 2019-12-15

1567 Background selection does not mimic the patterns of genetic diversity produced by selective sweeps

Schrider, D.

10.1101/2019.12.13.876136 — evolutionary biology — Posted on 2019-12-15

1568 Novel pelagiphages prevail in the ocean

Zhang, Z.; Qin, F.; Chen, F.; Chu, X.; Luo, H.; Zhang, R.; Du, S.; Tian, Z.; Zhao, Y.

10.1101/2019.12.14.876532 — ecology — Posted on 2019-12-15

1569 Yeast Securin is trafficked through the endomembrane system to regulate cell cycle arrest during the DNA damage response

Lemos, B.; Waterman, D. P.; Haber, J. E.

10.1101/2019.12.15.876896 — cell biology — Posted on 2019-12-15

1570 Discovery, optimization, and cellular activities of 2-(aroylamino)cinnamamide derivatives against colon cancer

Elhaggar, R. S.; Omar, A. M.; Safo, M. K.; Abdelghany, T. A.; Ahmed, M. H.; Boothello, R.; Patel, B. B.; Abdel-Bakky, M. S.; Malebari, A. M.; El-Araby, M. E.

10.1101/2019.12.15.876698 — cancer biology — Posted on 2019-12-15

1571 Clustering using Automatic Differentiation: Misspecified models and High-Dimensional Data

Kasa, S. R.; Rajan, V.

10.1101/2019.12.13.876326 — bioinformatics — Posted on 2019-12-15

1572 A comprehensive pipeline for accurate annotation and quantification of circRNAs

Kadener, S.; Rabin, A.; Ashwal-Fluss, R.; Shenzis, S.; Apelblat, D.

10.1101/2019.12.15.876755 — bioinformatics — Posted on 2019-12-15

1573 Mutation effect estimation on protein-protein interactions using deep contextualized representation learning

Zhou, G.; Chen, M.; Ju, C. J.-T.; Jiang, J.-Y.; Wang, Z.; Wang, W.

10.1101/2019.12.15.876953 — bioinformatics — Posted on 2019-12-15

1574 A Multi-Niche Microvascularized Human Bone-Marrow-on-a-Chip

Nelson, M. R.; Ghoshal, D.; Mejias, J. C.; Frey Rubio, D.; Keith, E.; Roy, K.

10.1101/2019.12.15.876813 — bioengineering — Posted on 2019-12-15

1575 Non-shared dispersal networks with heterogeneity promote species coexistence in hierarchical competitive metacommunities

Zhang, H.; Liao, J.

10.1101/2019.12.14.876383 — ecology — Posted on 2019-12-15

1576 Altered cortical gyrification in adults who were born very preterm and its associations with cognition and mental health

Papini, C.; Palaniyappan, L.; Kroll, J.; Froudist-Walsh, S.; Murray, R. M.; Nosarti, C.

10.1101/2019.12.13.871558 — neuroscience — Posted on 2019-12-15

1577 Extraction of near-complete genomes from metagenomic samples: a new service in PATRIC

Parrello, B.; Butler, R.; Chlenski, P.; Pusch, G. D.; Overbeek, R.

10.1101/2019.12.13.874651 — genomics — Posted on 2019-12-15

1578 Forelimb movements evoked by optogenetic stimulation of the macaque motor cortex

Watanabe, H.; Sano, H.; Chiken, S.; Kobayashi, K.; Fukata, Y.; Fukata, M.; Mushiake, H.; Nambu, A.

10.1101/2019.12.13.876219 — neuroscience — Posted on 2019-12-15

1579 An Extended Primer Grip of Picornavirus Polymerase Facilitates Sexual RNA Replication Mechanisms

Kempf, B. J.; Watkins, C. L.; Peersen, O.; Barton, D. J.

10.1101/2019.12.13.876292 — microbiology — Posted on 2019-12-15

1580 Growth rate alterations of human colorectal cancer cells by 157 gut bacteria

Taddese, R.; Garza, D. R.; Ruiter, L. N.; de Jonge, M.; Belzer, C.; Aalvink, S.; Nagtegaal, I. D.; Dutilh, B. E.; Boleij, A.

10.1101/2019.12.14.876367 — microbiology — Posted on 2019-12-15

1581 AlphaFamImpute: high accuracy imputation in full-sib families from genotype-by-sequencing data

Whalen, A.; Gorjanc, G.; Hickey, J. M.

10.1101/2019.12.11.872432 — genetics — Posted on 2019-12-15

1582 Global drivers of diversification in a marine species complex

Nunes Soares Silva, C.; Murphy, N. P.; Bell, J. J. B. J.; Green, B. S.; Duhamel, G.; Cockcroft, A. C.; Hernandez, C. E.; Strugnell, J. M.

10.1101/2019.12.13.874883 — evolutionary biology — Posted on 2019-12-15

1583 A transcriptomic continuum of differentiation arrest identifies myeloid interface acute leukemias with poor prognosis

Bond, J.; Krzywon, A.; Lhermitte, L.; Roumier, C.; Roggy, A.; Belhocine, M.; Kheirallah, A. K.; Villarese, P.; Hypolite, G.; Garnache-Ottou, F.; Castaigne, S.; Boissel, N.; Asnafi, V.; Preudhomme, C.; Dombret, H.; Laurenti, E.; Macintyre, E.

10.1101/2019.12.10.870121 — cancer biology — Posted on 2019-12-15

1584 No consistent evidence for microbiota in murine placental and fetal tissues

Theis, K. R.; Romero, R.; Greenberg, J. M.; Winters, A. D.; Garcia-Flores, V.; Motomura, K.; Ahmad, M. M.; Galaz, J.; Arenas-Hernandez, M.; Gomez-Lopez, N.

10.1101/2019.12.10.872275 — microbiology — Posted on 2019-12-15

1585 Nilotinib activates endothelial TLR4 to exacerbate atherosclerosis

Qu, D.; Huo, M.; Wang, L.; Lau, C.-W.; Tian, X. Y.; Huang, Y.

10.1101/2019.12.14.876599 — cell biology — Posted on 2019-12-15

1586 Symmetrically-dispersed spectroscopic single-molecule localization microscopy

Song, K.-H.; Zhang, Y.; Brenner, B.; Sun, C.; Zhang, H. F.

10.1101/2019.12.14.876557 — biophysics — Posted on 2019-12-15

1587 Attractor dynamics gate cortical information flow during decision-making

Finkelstein, A.; Fontolan, L.; Economo, M. N.; Li, N.; Romani, S.; Svoboda, K.

10.1101/2019.12.14.876425 — neuroscience — Posted on 2019-12-15

1588 BACH family members regulate angiogenesis and lymphangiogenesis by modulating VEGFC expression

Cohen, B.; Tempelhof, H.; Raz, T.; Oren, R.; Nicenboim, J.; Bochner, F.; Even, R.; Jelinski, A.; Eilam, R.; Ben-Dor, S.; Addadi, Y.; Golani, O.; Lazar, S.; Yaniv, K.; Neeman, M.

10.1101/2019.12.13.876268 — developmental biology — Posted on 2019-12-15

1589 The anti-leishmanial activity of Spergulin-A involves P2X7R-P38MAPK axis

Mukherjee, N.; Banerjee, S.; Amin, S. A.; Jha, T.; Datta, S.; Das Saha, K.

10.1101/2019.12.14.876391 — molecular biology — Posted on 2019-12-15

1590 PlasClass improves plasmid sequence classification

Pellow, D.; Mizrahi, I.; Shamir, R.

10.1101/783571 — bioinformatics — Posted on 2019-12-15

1591 Intra-strain elicitation and suppression of plant immunity by Ralstonia solanacearum type-III effectors in Nicotiana benthamiana

Sang, Y.; Yu, W.; Zhuang, H.; Wei, Y.; Derevnina, L.; Yu, G.; Luo, J.; Macho, A.

10.1101/780890 — plant biology — Posted on 2019-12-15

1592 Programmable CRISPR interference for gene silencing using Cas13a in mosquitoes

Kulkarni, A.; Yu, W.; Moon, A. S.; Pandey, A.; Hanley, K. A.; Xu, J.

10.1101/846055 — molecular biology — Posted on 2019-12-15

1593 Purging of highly deleterious mutations through severe bottlenecks in Alpine ibex

Grossen, C.; Guillaume, F.; Keller, L. F.; Croll, D.

10.1101/605147 — evolutionary biology — Posted on 2019-12-15

1594 Mycobacterium tuberculosis Modulates the Metabolism of Alternatively Activated Macrophages to Promote Foam Cell Formation and Intracellular Survival

Genoula, M.; Marin Franco, J. L.; Maio, M.; Dolotowicz, B.; Ferreyra, M.; Milillo, M. A.; Mascarau, R.; Morana, E. J.; Palmero, D.; Fuentes, F.; Lopez, B.; Barrionuevo, P.; Neyrolles, O.; Cougoule, C.; Lugo-Villarino, G.; Verollet, C.; Sasiain, M.; Balboa, L.

10.1101/2019.12.13.876300 — immunology — Posted on 2019-12-14

1595 Relative model fit does not predict accuracy in single-gene protein phylogenetics

Spielman, S.

10.1101/698860 — evolutionary biology — Posted on 2019-12-14

1596 Natural scene statistics predict how humans pool information across space in the estimation of surface tilt

Kim, S.; Burge, J.

10.1101/870618 — neuroscience — Posted on 2019-12-14

1597 Comparative genomic analysis of Cristatella mucedo provides insights into Bryozoan evolution and nervous system function

Starunov, V. V.; Predeus, A. V.; Barbitoff, Y. A.; Kutiumov, V. A.; Maltseva, A. L.; Vodiasova, E. A.; Kohn, A. B.; Moroz, L. L.; Ostrovsky, A. N.

10.1101/869792 — genomics — Posted on 2019-12-14

1598 Riboflow: using deep learning to classify riboswitches with ~99% accuracy

Premkumar, K. A. R.; Bharanikumar, R.; Palaniappan, A.

10.1101/868695 — bioinformatics — Posted on 2019-12-14

1599 Revealing the structure of information flows discriminates similar animal social behaviors

Valentini, G.; Mizumoto, N.; Pratt, S. C.; Pavlic, T. P.; Walker, S. I.

10.1101/765198 — animal behavior and cognition — Posted on 2019-12-14

1600 A novel network controllability algorithm to target personalized driver genes for discovering combinational drugs of individual cancer patient

Guo, W.; Zhang, S.-W.; Zeng, T.; Chen, L.

10.1101/571620 — systems biology — Posted on 2019-12-14

1601 The reconstruction and functional mapping of a recurrent microcircuit in Drosophila mushroom body

Xia, W. G.; Yu, Z. B.; Xiong, W. S.; Kai, Y.; Jian, Z. J.; Yang, X.; Ming, L. Y.; Jun, S. L.

10.1101/819227 — neuroscience — Posted on 2019-12-14

1602 Nuclear encoded photosynthesis genes are specifically controlled by the NuA4 complex

Bieluszewski, T.; Sura, W.; Bieluszewska, A.; Kabza, M.; Abram, M.; Wlodzimierz, P.; Dziegielewski, W.; Szymanska-Lejman, M.; Lachance, C.; De Winne, N.; De Jaeger, G.; Cote, J.; Sadowski, J.; Ziolkowski, P. A.

10.1101/846592 — molecular biology — Posted on 2019-12-14

1603 Dual-stage-processed 3D network super-resolution for volumetric fluorescence microscopy far beyond throughput limit

Zhang, H.; Zhao, Y.; Fang, C.; Li, G.; Li, Y.; Zhang, M.; Li, Y.; Wan, P.; Yu, T.; Zhang, Y.; Zhu, D.; Gao, S.; Fei, P.

10.1101/435040 — biophysics — Posted on 2019-12-14

1604 Molecular basis of CTCF binding polarity in genome folding

Nora, E. P.; Caccianini, L.; Fudenberg, G.; Kameswaran, V.; Nagle, A.; Uebersohn, A.; So, K.; Hajj, B.; Le Saux, A.; Coulon, A.; Mirny, L. A.; Pollard, K. S.; Dahan, M.; Bruneau, B. G.

10.1101/2019.12.13.876177 — molecular biology — Posted on 2019-12-14

1605 Blimp-1 in adipose resident Tregs controls adipocyte beiging and obesity

Beppu, L. Y.; Qu, X.; Marrero, G. J.; Fooks, A. N.; Frias, A. B.; Helfrich, K. E.; Sipula, I.; Xie, B.; Watkins, S. C.; Poholek, A. C.; Jurczak, M. J.; D'Cruz, L. M.

10.1101/2019.12.14.874693 — immunology — Posted on 2019-12-14

1606 Ribosome biogenesis is a downstream effector of the oncogenic U2AF1-S34F mutation

Akef, A.; Cappell, S. D.; Larson, D. R.

10.1101/2019.12.13.876284 — cell biology — Posted on 2019-12-14

1607 Wss1 promotes replication stress tolerance by degrading histones.

Maddi, K.; Sam, D. K.; Bonn, F.; Prgomet, S.; Tulowetzke, E.; Akutsu, M.; Lopez-Mosqueda, J.; Dikic, I.

10.1101/2019.12.13.876110 — cell biology — Posted on 2019-12-14

1608 Motion denoising of multiband resting state functional connectivity MRI data: An improved volume censoring method

Williams, J. C.; Van Snellenberg, J. X.

10.1101/860635 — neuroscience — Posted on 2019-12-14

1609 Robust neural control of virtual locomotion enabled by a novel decoding strategy

Schroeder, K. E.; Perkins, S. M.; Wang, Q.; Churchland, M. M.

10.1101/2019.12.13.862532 — neuroscience — Posted on 2019-12-14

1610 The importance of Indigenous Peoples' lands for the conservation of terrestrial vertebrates

O'Bryan, C. J.; Garnett, S. T.; Fa, J. E.; Leiper, I.; Rehbein, J.; Fernandez-Llamazares, A.; Jackson, M. V.; Jonas, H. D.; Brondizio, E. S.; Burgess, N. D.; Robinson, C. J.; Zander, K. K.; Venter, O.; Watson, J. E. M.

10.1101/2019.12.11.873695 — ecology — Posted on 2019-12-14

1611 Simultaneous SNP selection and adjustment for population structure in high dimensional prediction models

Bhatnagar, S. R.; Yang, Y.; Lu, T.; Schurr, E.; Loredo-Osti, J.; Forest, M.; Oualkacha, K.; Greenwood, C. M.

10.1101/408484 — bioinformatics — Posted on 2019-12-14

1612 Optimal Experimental Design for Big Data: Applications in Brain Imaging

Bridgeford, E. W.; Wang, S.; Yang, Z.; Wang, Z.; Xu, T.; Craddock, C.; Dey, J.; Kiar, G.; Gray-Roncal, W.; Priebe, C. E.; Caffo, B.; Milham, M.; Zuo, X.-N.; Consortium for Reliability and Reproducibility, ; Vogelstein, J. T.

10.1101/802629 — neuroscience — Posted on 2019-12-14

1613 The emergent Yo-yo movement of nuclei driven by collective cytoskeletal remodeling in pseudo-synchronous mitotic cycles

Lv, Z.; Rosenbaum, J.; Mohr, S.; Zhang, X.; Deqing, K.; Preiss, H.; Kruss, S.; Alim, K.; Aspelmeier, T.; Grosshans, J.

10.1101/662965 — developmental biology — Posted on 2019-12-14

1614 Polyandry and paternity affect disease resistance in eusocial wasps - support for the pathogen parasite hypothesis

Saga, T.; Okuno, M.; Loope, K. J.; Tsuchida, K.; Ohbayashi, K.; Shimada, M.; Okada, Y.

10.1101/869537 — animal behavior and cognition — Posted on 2019-12-14

1615 Estimates of abundance and change in abundance of the Indo-Pacific bottlenose dolphins (Tursiops aduncus) along the south coast of South Africa

Vargas Fonseca, O. A.; Kirkman, S. P.; Oosthuizen, W. C.; Bouveroux, T.; Cockcroft, V.; Conry, D.; Pistorius, P.

10.1101/2019.12.13.875179 — zoology — Posted on 2019-12-13

1616 Visual impairment, spectacle wear and academic performance among junior high school students in western China

Nie, J.; Nie, W.; Mu, M.; Zhang, L.; Song, S.; Peng, L.; Gao, Q.; Yang, J.

10.1101/2019.12.13.875153 — scientific communication and education — Posted on 2019-12-13

1617 The urinary microbiota composition remains stable over time and under various storage conditions

Bundgaard-Nielsen, C.; Ammitzboll, N.; Isse, Y. A.; Muqtar, A.; Jensen, A.-M.; Leutscher, P.; Arenholt, L. T. S.; Hagstrom, S.; Sorensen, S.

10.1101/2019.12.13.875187 — microbiology — Posted on 2019-12-13

1618 Estimating densities of larval Salmonflies (Pteronarcys californica) through multiple pass removal of post-emergent exuvia in Colorado rivers.

Heinold, B.; Kowalski, D. A.; Nehring, R. B.

10.1101/2019.12.13.875195 — ecology — Posted on 2019-12-13

1619 Anillin/Mid1p interacts with the ECSRT-associated protein Vps4p and mitotic kinases to regulate cytokinesis in fission yeast

McInerny, C.; Rezig, I.; Gould, G.

10.1101/2019.12.13.875211 — cell biology — Posted on 2019-12-13

1620 RosettaGPCR: Multiple Template Homology Modeling of GPCRs with Rosetta

Bender, B.; Marlow, B.; Meiler, J.

10.1101/2019.12.13.875237 — bioinformatics — Posted on 2019-12-13

1621 Overprecision Increases Subsequent Surprise

Schatz, D.; Moore, D. A.

10.1101/2019.12.13.875203 — animal behavior and cognition — Posted on 2019-12-13

1622 Prevalence, risk factors and health seeking behaviour of pulmonary tuberculosis in four tribal dominated districts of Odisha

HUSSAIN, T.; TRIPATHY, S. S.; DAS, S.; Das, D.; Thomas, B.

10.1101/2019.12.13.875252 — microbiology — Posted on 2019-12-13

1623 Quantification of guanosine tetraphosphate and other nucleotides in plants and algae using stable isotope-labelled internal standards.

Bartoli, J.; Citerne, S.; Mouille, G.; Bouveret, E.; Field, B.

10.1101/2019.12.13.875492 — plant biology — Posted on 2019-12-13

1624 Multiomic and quantitative label-free microscopy-based analysis of ex vivo culture and TGFbeta1 stimulation of human precision-cut lung slices

Khan, M. M.; Poeckel, D.; Halavatyi, A.; Stein, F.; Vappiani, J.; Sevin, D. C.; Tischer, C.; Zinn, N.; Eley, J. D.; Gudmann, N. S.; Muley, T.; Winter, H.; Fisher, A. J.; nanthakumar, C. B.; Bergamini, G.; Pepperkok, R.

10.1101/2019.12.13.875963 — physiology — Posted on 2019-12-13

1625 Structure and function of a neocortical synapse

Holler-Rickauer, S.; Koestinger, G.; Martin, K. A. C.; Schuhknecht, G. F. P.; Stratford, K. J.

10.1101/2019.12.13.875971 — neuroscience — Posted on 2019-12-13

1626 PULL-PUSH NEUROMODULATION OF CORTICAL PLASTICITY ENABLES RAPID BI-DIRECTIONAL SHIFTS IN OCULAR DOMINANCE

Hong, S.; huang, S.; Severin, D.; kirkwood, a.

10.1101/2019.12.13.875849 — neuroscience — Posted on 2019-12-13

1627 Novel splicing and open reading frames revealed by long-read direct RNA sequencing of adenovirus transcripts

Price, A. M.; Hayer, K. E.; Depledge, D. P.; Wilson, A. C.; Weitzman, M. D.

10.1101/2019.12.13.876037 — microbiology — Posted on 2019-12-13

1628 Epigenetically bistable regions across neuron-specific genes govern neuron eligibility to a coding ensemble in the hippocampus

Shannon, O. C.; Taki, F.; Klein, S.; Chen, R. J.; Levine, O. B.; Skelly, M. J.; Nabila, A.; Brindley, E.; Gal Toth, J.; Dundar, F.; Sheridan, C. K.; Fetcho, R. N.; Alonso, A.; Liston, C.; Landau, D. A.; Pleil, K.; Toth, M.

10.1101/2019.12.13.874347 — neuroscience — Posted on 2019-12-13

1629 A novel Arabidopsis phyllosphere resident Protomyces sp. and a re-examination of genus Protomyces based on genome sequence data.

Wang, K.; Sipilä, T.; Overmyer, K.

10.1101/2019.12.13.875955 — microbiology — Posted on 2019-12-13

1630 HIV corrupts the Cdc42-IQGAP1 axis of actin regulation to promote cell-cell viral spread

Aggarwal, A.; Ospina Stella, A.; Henry, C. C.; Narayan, K.; Turville, S. G.

10.1101/2019.12.13.873612 — microbiology — Posted on 2019-12-13

1631 Ecological drivers of African swine fever virus persistence in wild boar populations: insight for control

Pepin, K. M.; Golnar, A.; Abdo, Z.; Podgorski, T.

10.1101/2019.12.13.875682 — ecology — Posted on 2019-12-13

1632 TF protein of Sindbis virus antagonizes host type I interferon responses in a palmitoylation-dependent manner

Rogers, K.; Jones-Burrage, S.; Maury, W.; Mukhopadhyay, S.

10.1101/2019.12.13.875781 — microbiology — Posted on 2019-12-13

1633 Tuning shape and internal structure of protein droplets via biopolymer filaments

Scheff, D. R.; Weirich, K. L.; Dasbiswas, K.; Patel, A.; Vaikuntanathan, S.; Gardel, M. L.

10.1101/2019.12.13.876003 — biophysics — Posted on 2019-12-13

1634 Broccoli: combining phylogenetic and network analyses for orthology assignment

derelle, r.; Philippe, H.; Colbourne, J. K.

10.1101/2019.12.13.875831 — bioinformatics — Posted on 2019-12-13

1635 Enhanced prediction of cognitive function using aging-sensitive networks within the human structural connectome

Madole, J. W.; Ritchie, S. J.; Cox, S. R.; Buchanan, C. R.; Valdes Hernandez, M.; Munoz Maniega, S. R.; Wardlaw, J. M.; Harris, M. A.; Bastin, M. E.; Deary, I. J.; Tucker-Drob, E. M.

10.1101/2019.12.13.875559 — neuroscience — Posted on 2019-12-13

1636 Unexpected diversity of CRISPR unveils some evolutionary patterns of repeated sequences in Mycobacterium tuberculosis

Refregier, G.; Sola, C.; Guyeux, C.

10.1101/2019.12.13.875765 — microbiology — Posted on 2019-12-13

1637 Cdc48 Co-Factor Shp1 Regulates Signal-Induced SCFMet30 Disassembly

Lauinger, L.; Flick, K.; Yen, J. L.; Mathur, R.; Kaiser, P.

10.1101/2019.12.13.876029 — biochemistry — Posted on 2019-12-13

1638 A simple circuit model of visual cortex explains neural and behavioral aspects of attention

Lindsay, G. W.; Rubin, D. B.; Miller, K. D.

10.1101/2019.12.13.875534 — neuroscience — Posted on 2019-12-13

1639 Effects of fluorescent glutamate indicators on neurotransmitter diffusion and uptake

Armbruster, M.; Dulla, C. G.; Diamond, J. S.

10.1101/2019.12.13.875724 — neuroscience — Posted on 2019-12-13

1640 Visualization of two architectures in class-II CAP-dependent transcription activation

Shi, W.; Jiang, Y.; Deng, Y.; Dong, Z.; Liu, B.

10.1101/2019.12.13.875658 — molecular biology — Posted on 2019-12-13

1641 Origin Specific Genomic Selection: a simple process to optimize the favourable contribution of parents to progeny

Yang, C. J.; Sharma, R.; Gorjanc, G.; Hearne, S.; Powell, W.; Mackay, I.

10.1101/2019.12.13.875690 — genetics — Posted on 2019-12-13

1642 Comparison of mechanical sorting and DNA metabarcoding for diet analysis with degraded wolf scats

Massey, A. L.; Roffler, G.; Vermeul, T.; Allen, J. M.; Levi, T.

10.1101/2019.12.13.875898 — ecology — Posted on 2019-12-13

1643 Global gene expression patterns in response to white patch syndrome: Disentangling symbiont loss from the thermal stress response in reef-building coral

Kenkel, C. D.; Mocellin, V. J. L.; Bay, L. K.

10.1101/2019.12.13.875989 — ecology — Posted on 2019-12-13

1644 TGFβ superfamily signaling regulates the state of human stem cell pluripotency and competency to create telencephalic organoids

Watanabe, M.; Haney, J. R.; Vishlaghi, N.; Turcios, F.; Buth, J. E.; Gu, W.; Collier, A. J.; Miranda, O. A.; Chen, D.; Sabri, S.; Clark, A. T.; Plath, K.; Christofk, H. R.; Gandal, M. J.; Novitch, B. G.

10.1101/2019.12.13.875773 — developmental biology — Posted on 2019-12-13

1645 An Alignment-free Method for Phylogeny Estimation using Maximum Likelihood

Zahin, T.; Abrar, M. H.; Rahman, M.; Tasnim, T.; Bayzid, M. S.; Rahman, A.

10.1101/2019.12.13.875526 — bioinformatics — Posted on 2019-12-13

1646 Survey of Public Assay Data: Opportunities and Challenges to Understanding Antimicrobial Resistance

Agarwal, A.; Nayar, G.; Kaufman, J.

10.1101/2019.12.13.874909 — bioinformatics — Posted on 2019-12-13

1647 A novel drug-inducible sex-separation technique for insects

Kandul, N. P.; Liu, J.; Hsu, A. D.; Hay, B. A.; Akbari, O. S.

10.1101/2019.12.13.875716 — genetics — Posted on 2019-12-13

1648 Representation of semantic information in ventral areas during encoding is associated with improved visual short-term memory

Stojanoski, B.; Emrich, S. M.; Cusack, R.

10.1101/2019.12.13.875542 — neuroscience — Posted on 2019-12-13

1649 Staphylococcal Enterotoxin C promotes Staphylococcus aureus Infective Endocarditis Independent of Superantigen Activity

Kinney, K. J.; Tran, P. M.; Gibson-Corley, K. N.; Forsythe, A. N.; Kulhankova, K.; Salgado-Pabon, W.

10.1101/2019.12.13.875633 — microbiology — Posted on 2019-12-13

1650 Intellectual disability-associated factor Zbtb11 cooperates with NRF-2/GABP to control mitochondrial function

Wilson, B. C.; Boehme, L.; Annibali, A.; Hodgkinson, A.; Carroll, T. S.; Oakey, R. J.; Seitan, V. C.

10.1101/2019.12.13.875708 — cell biology — Posted on 2019-12-13

1651 Non-ionic CT Contrast Solutions Rapidly Alter Bovine Cartilage and Meniscus Mechanics

Baylon, E. G.; Crowder, H. A.; Gold, G. E.; Levenston, M. E.

10.1101/2019.12.13.874743 — bioengineering — Posted on 2019-12-13

1652 Fatty acid synthesis in satellite glial cell promotes regenerative growth in sensory neurons

Avraham, O.; Deng, P.-Y.; Jones, S.; Kuruvilla, R.; Semenkovich, C. F.; Klyachko, V. A.; Cavalli, V.

10.1101/2019.12.13.874669 — neuroscience — Posted on 2019-12-13

1653 Intravital quantification of absolute cytoplasmic B cell calcium reveals dynamic signaling across B cell differentiation stages

Ulbricht, C.; Leben, R.; Rakhymzhan, A.; Kirchhoff, F.; Nitschke, L.; Radbruch, H.; Niesner, R. A.; Hauser, A. E.

10.1101/2019.12.13.872820 — immunology — Posted on 2019-12-13

1654 Functional genomics of the parasitic habits of blowflies and botflies

Cardoso, G. A.; Deszo, M. S.; Torres, T. T.

10.1101/2019.12.13.871723 — genetics — Posted on 2019-12-13

1655 Finding ranges of optimal transcript expression quantification in cases of non-identifiability

Ma, C.; Zheng, H.; Kingsford, C.

10.1101/2019.12.13.875625 — bioinformatics — Posted on 2019-12-13

1656 The effect of feeding behavior of Monochamus alternatus (Coleoptera: Cerambycidae) on the departure of pine wood nematode, Bursaphelenchus xylophilus (Nematoda: Aphelenchoididae)

Wang, Y.; Chen, F.; Wang, L.; Zhou, L.; Song, J.

10.1101/2019.12.13.875575 — animal behavior and cognition — Posted on 2019-12-13

1657 Unconventional kinetochore kinases KKT2 and KKT3 have a unique zinc finger that promotes their kinetochore localization

Marciano, G.; Nerusheva, O. O.; Ishii, M.; Akiyoshi, B.

10.1101/2019.12.13.875419 — cell biology — Posted on 2019-12-13

1658 ExpansionHunter Denovo: A computational method for locating known and novel repeat expansions in short-read sequencing data

Dolzhenko, E.; Bennett, M. F.; Richmond, P. A.; Trost, B.; Chen, S.; van Vugt, J. J.; Nguyen, C.; Narzisi, G.; Gainullin, V. G.; Gross, A.; Lajoie, B.; Taft, R. J.; Wasserman, W. W.; Scherer, S. W.; Veldink, J. H.; Bentley, D. R.; Yuen, R. K.; Bahlo, M.; Eberle, M. A.

10.1101/863035 — bioinformatics — Posted on 2019-12-13

1659 Structurally informed evolutionary models improve phylogenetic reconstruction for emerging, seasonal, and pandemic influenza viruses

Qiu, X.; Bahl, J.

10.1101/228692 — evolutionary biology — Posted on 2019-12-13

1660 Surprising variation in the outcome of two malaria genetic crosses using humanized mice: implications for genetic mapping and malaria biology

Button-Simons, K. A.; Kumar, S.; Carmago, N.; Haile, M. T.; Jett, C.; Checkley, L. A.; Kennedy, S. Y.; Pinapati, R. S.; Shou, D. A.; McDew-White, M.; Li, X.; Nosten, F. H.; Kappe, S. H.; Anderson, T. J. C.; Romero-Severson, J. A.; Ferdig, M. T.; Emrich, S.; Vaughan, A. M.; Cheeseman, I. H.

10.1101/2019.12.13.871830 — genetics — Posted on 2019-12-13

1661 Honeybees adjust colour preferences in response to concurrent social information from conspecifics and heterospecifics

Romero-Gonzalez, J. E.; Perry, C. J.; Chittka, L.

10.1101/2019.12.12.874917 — animal behavior and cognition — Posted on 2019-12-13

1662 Low-Latitude Origins of the Four Phanerozoic Evolutionary Faunas

Rojas, A.; Calatayud, J.; Kowalewski, M.; Neuman, M.; Rosvall, M.

10.1101/866186 — paleontology — Posted on 2019-12-13

1663 Flapping at Resonance: Measuring the Frequency Response of the Hymenoptera Thorax

Jankauski, M.

10.1101/2019.12.11.873562 — bioengineering — Posted on 2019-12-13

1664 Characterization of the adaptation to visuomotor rotations in the muscle synergies space

Severini, G.; Zych, M.

10.1101/2019.12.12.873802 — bioengineering — Posted on 2019-12-13

1665 Color tuning of neurons in face patches of macaque inferior temporal cortex

Duyck, M.; Gruen, T.; Tello, L.; Eastman, S.; Fuller-Deets, J.; Conway, B.

10.1101/863779 — neuroscience — Posted on 2019-12-13

1666 The dengue virus non-structural protein 1 (NS1) use the scavenger receptor B1 as cell receptor in human hepatic and mosquito cells

Alcala, A. C.; Maravillas, J. L.; Meza, D.; Ramirez, O. T.; Ludert, J. E.; Palomares, L. A.

10.1101/871988 — microbiology — Posted on 2019-12-13

1667 An unsupervised feature extraction and selection strategy for identifying epithelial-mesenchymal transition state metrics in breast cancer and melanoma

Klinke, D. J.; Torang, A.

10.1101/865139 — cancer biology — Posted on 2019-12-13

1668 Quantum coherence in the photosynthesis apparatus of living cyanobacteria

Rammler, T. D.; Wackenhut, F.; zur Oven-Krockhaus, S.; Rapp, J.; Forchhammer, K.; Harter, K. J. W.; Meixner, A. J.

10.1101/2019.12.13.875344 — biophysics — Posted on 2019-12-13

1669 Investigations into the declining health of alder (Alnus glutinosa) along the river Lagan in Belfast, including the first report of Phytophthora lacustris causing disease of Alnus in Northern Ireland

O'Hanlon, R.; Wilson, J.; Cox, D.

10.1101/2019.12.13.875229 — plant biology — Posted on 2019-12-13

1670 HDAC inhibition ameliorates cone survival in retinitis pigmentosa mice

Samardzija, M.; Corna, A.; Gomez-Sintes, R.; Jarboui, M. A.; Armento, A.; Roger, J. E.; Petridou, E.; Haq, W.; Paquet-Durand, F.; Zrenner, E.; Zeck, G.; Grimm, C.; Boya, P.; Ueffing, M.; Trifunovic, D.

10.1101/2019.12.13.874339 — neuroscience — Posted on 2019-12-13

1671 Probability waves: pattern-based p-value correction in mass univariate analysis between two event-related potential waves.

Abramov, D. M.

10.1101/2019.12.12.873570 — neuroscience — Posted on 2019-12-13

1672 Heterogeneity and targeted therapy-induced adaptations in lung cancer revealed by longitudinal single-cell RNA sequencing

Maynard, A.; McCoach, C. E.; Rotow, J. K.; Harris, L.; Haderk, F.; Kerr, L. D.; Yu, E. A.; Schenk, E. L.; Tan, W.; Zee, A.; Tan, M.; Gui, P.; Lea, T.; Wu, W.; Urisman, A.; Jones, K.; Sit, R.; Kolli, P. K.; Seeley, E.; Gesthalter, Y.; Le, D. D.; Yamauchi, K. A.; Naeger, D. M.; Thomas, N. J.; Gupta, A.; Gonzalez, M.; Do, H.; Tan, L.; Gomez-Sjoberg, R.; Gubens, M.; Jahan, T.; Kratz, J. R.; Jablons, D.; Neff, N.; Doebele, R. C.; Weissman, J.; Blakely, C. M.; Darmanis, S.; Bivona, T. G.

10.1101/2019.12.08.868828 — cancer biology — Posted on 2019-12-13

1673 Honeybees adjust colour preferences in response to concurrent social information from conspecifics and heterospecifics

Romero-Gonzalez, J.; Perry, C. J.; Chittka, L.

10.1101/2019.12.12.874917 — animal behavior and cognition — Posted on 2019-12-13

1674 Hemocyte-targeted gene expression in the female malaria mosquito using the hemolectin promoter from Drosophila

Pondeville, E.; Puchot, N.; Parvy, J.-P.; Carissimo, G.; Poidevin, M.; Waterhouse, R. M.; Marois, E.; Bourgouin, C.

10.1101/2019.12.13.875518 — genetics — Posted on 2019-12-13

1675 CRK2 and C-terminal phosphorylation of NADPH oxidase RBOHD regulate ROS production in Arabidopsis

Kimura, S.; Hunter, K.; Vaahtera, L.; Tran, H. C.; Citterico, M.; Vaattovaara, A.; Rokka, A.; Stolze, S. C.; Harzen, A.; Meissner, L.; Wilkens, M. M. T.; Hamann, T.; Toyota, M.; Nakagami, H.; Wrzaczek, M.

10.1101/618819 — plant biology — Posted on 2019-12-13

1676 Functional Analysis of the UV-B Photoreceptor Gene ZmUVR8 (UVR8 Response locus), from Zea Mays.

Fernandez, M. B.; Lamattina, L.; Cassia, R.

10.1101/649905 — plant biology — Posted on 2019-12-13

1677 Visual pathways in the brain of the jumping spider Marpissa muscosa

Steinhoff, P. O. M.; Uhl, G.; Harzsch, S.; Sombke, A.

10.1101/640706 — neuroscience — Posted on 2019-12-13

1678 Expectations affect the perception of material properties

Alley, L. M.; Schmid, A. C.; Doerschner, K.

10.1101/744458 — neuroscience — Posted on 2019-12-13

1679 Alcohol Drinking Alters Stress Coping via Extended Amygdala Kappa Opioid Receptor Signaling in Male Mice

Hwa, L. S.; Neira, S.; Flanigan, M. E.; Stanhope, C. M.; Pina, M. M.; Pati, D. S.; Hon, O. J.; Yu, W.; Kokush, E.; Calloway, R.; Boyt, K.; Kash, T. L.

10.1101/773481 — neuroscience — Posted on 2019-12-13

1680 A waveguide imaging platform for live-cell TIRF imaging of neurons over large fields of view

Opstad, I. S.; Strohl, F.; Fantham, M.; Hockings, C.; Vanderpoorten, O.; Tartwijk, F. v.; Lin, J. Q.; Tinguely, J.-C.; Dullo, F. T.; Kaminski-Schierle, G. S.; Ahluwalia, B. S.; Kaminski, C. F.

10.1101/2019.12.13.874545 — neuroscience — Posted on 2019-12-13

1681 Detection for suspected Genetically Modified Maize and Soybean crops in the selected places of Ethiopia using PCR machine

Admas, A.; Melese, S.; Genetu, A.

10.1101/2019.12.12.874974 — molecular biology — Posted on 2019-12-13

1682 Development and Optimisation of a Defined High Cell Density Yeast Medium

Roberts, T. M.; Kaltenbach, H.-M.; Fabian, R.

10.1101/846006 — microbiology — Posted on 2019-12-13

1683 Evolution in interacting species alters predator life history traits, behavior and morphology in experimental microbial communities

Cairns, J.; Moerman, F.; Fronhofer, E. A.; Altermatt, F.; Hiltunen, T.

10.1101/748582 — evolutionary biology — Posted on 2019-12-13

1684 Matching the forecast horizon with the relevant spatial and temporal processes and data sources

Adler, P.; White, E.; Cortez, M.

10.1101/807057 — ecology — Posted on 2019-12-13

1685 Quantifying geographic accessibility to improve efficiency of entomological monitoring.

Longbottom, J.; Krause, A.; Torr, S. J.; Stanton, M. C.

10.1101/779561 — ecology — Posted on 2019-12-13

1686 Rethinking global carbon storage potential of trees. A comment on Bastin et al. 2019

Taylor, S. D.; Marconi, S.

10.1101/730325 — ecology — Posted on 2019-12-13

1687 Ki-67 promotes sequential stages of tumourigenesis by enabling cellular plasticity

Mrouj, K.; Singh, P.; Sobecki, M.; Dubra, G.; Al Ghoul, E.; Aznar, A. B.; prieto, S.; Pirot, N.; Bernex, F.; Bordignon, B.; Hassen-Khodja, C.; Pouzolles, M.; Zimmerman, V.; Dardalhon, V.; Krasinska, L.; Fisher, D.

10.1101/712380 — cancer biology — Posted on 2019-12-13

1688 The Noise-Resilient Brain: Resting-State Oscillatory Activity Predicts Words-In-Noise Recognition

Houweling, T.; Becker, R.; Hervais-Adelman, A.

10.1101/705053 — neuroscience — Posted on 2019-12-13

1689 Genome-wide genetic risk for SLE and disease severity

Chen, L.; Wang, Y.-F.; Liu, L.; Bielowka, A.; Ahmed, R.; Zhang, H.; Tombleson, P.; Roberts, A. L.; Odhams, C. A.; Cunninghame Graham, D. S.; Zhang, X.; Yang, W.; Vyse, T. J.; Morris, D. L.

10.1101/614867 — genetics — Posted on 2019-12-13

1690 CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake.

McEwan, A. R.; Davidson, C.; Hay, E.; Turnbull, Y.; Erickson, J. C.; Marini, P.; Wilson, D.; McIntosh, A.; Adams, M. J.; Murgatroyd, C.; Barrett, P.; Delibegovic, M.; Clarke, T.-K.; MacKenzie, A.

10.1101/572065 — genetics — Posted on 2019-12-13

1691 Out of the Qinghai-Tibetan Plateau and get flourishing - the evolution of Neodon voles (Rodentia: Cricetidae) revealed by systematic sampling and low coverage whole genome sequencing

Liu, S.; Zhou, C.; WAN, T.; Meng, G.; Murphy, R. W.; Fan, Z.; Tang, M.; Liu, Y.; Zeng, T.; Chen, S.; Zhao, Y.; Liu, S.

10.1101/2019.12.12.873679 — zoology — Posted on 2019-12-13

1692 YSL3-mediated copper distribution is required for fertility, grain yield, and size in Brachypodium.

Sheng, H.; Jiang, Y.; Rahmati Ishka, M.; Chia, J.-C.; Dokuchayeva, T.; Kavulych, Y.; Zavodna, T.-O.; Mendoza, P. N.; Huang, R.; Smieshka, L. M.; Woll, A. R.; Terek, O. I.; Romanyuk, N. D.; Zhou, Y.; Vatamaniuk, O. K.

10.1101/2019.12.12.874396 — plant biology — Posted on 2019-12-13

1693 Water uptake analysis in Japanese mustard spinach: A numerical approach

Shimada, A.; Seki, T.; Ichikawa, M.

10.1101/2019.12.13.875005 — plant biology — Posted on 2019-12-13

1694 Developmental programming: Transcriptional regulation of visceral and subcutaneous adipose by prenatal bisphenol-A in female sheep

Dou, J. F.; Puttabyatappa, M.; Padmanabhan, V.; Bakulski, K.

10.1101/2019.12.12.874446 — pharmacology and toxicology — Posted on 2019-12-13

1695 Voluntary and involuntary orienting of attention elicit similar lateralized changes in alpha activity and slow potential shifts over visual cortex

Keefe, J. M.; Stoermer, V. S.

10.1101/2019.12.12.874818 — neuroscience — Posted on 2019-12-13

1696 Early life adversity and borderline intellectual functioning negatively impact limbic system connectivity in childhood: a connectomics-based study

Blasi, V.; Pirastru, A.; Cabinio, M.; Di Tella, S.; Lagana, M. M.; Giangiacomo, A.; Baglio, G.; Zanette, M.; Canevini, M. P.; Walder, M.; Clerici, M.; Baglio, F.

10.1101/2019.12.13.875161 — neuroscience — Posted on 2019-12-13

1697 Identification of two aptamers binding to Legionella pneumophila with high affinity and specificity

Saad, M.; Tabrizian, M.; Chinerman, D.; Faucher, S. P.

10.1101/2019.12.13.875476 — microbiology — Posted on 2019-12-13

1698 STING controls Herpes Simplex Virus in vivo independent of type I interferon induction

Yamashiro, L. H.; Wilson, S. C.; Morrison, H. M.; Karalis, V.; Chung, J.-Y. J.; Chen, K. J.; Bateup, H.; Szpara, M. L.; Lee, A. Y.; Cox, J. S.; Vance, R.

10.1101/2019.12.12.874792 — immunology — Posted on 2019-12-13

1699 Recent hybridization and allopolyploidy reprogrammed Spartina microRNA expression under xenobiotic induced stress.

Cave-Radet, A.; Salmon, A.; Tran Van Canh, L.; Moyle, R.; Pretorius, L.-S.; Lima, O.; Ainouche, M.; El Amrani, A.

10.1101/2019.12.13.875138 — evolutionary biology — Posted on 2019-12-13

1700 Integration of system phenotypes in microbiome networks to identify candidate synthetic communities: a study of the grafted tomato rhizobiome

Poudel, R.; Jumpponen, A.; Kennelly, M.; Rivard, C.; Gomez-Montano, L.; Garrett, K. A.

10.1101/2019.12.12.874966 — ecology — Posted on 2019-12-13

1701 MinYS: Mine Your Symbiont by targeted genome assembly in symbiotic communities

Guyomar, C.; Delage, W.; Legeai, F.; Mougel, C.; Simon, J.-C.; Lemaitre, C.

10.1101/2019.12.13.875021 — bioinformatics — Posted on 2019-12-13

1702 Fast and accurate defocus for improved tunability of cryo-EM experiments

Danev, R.; Iijima, H.; Matsuzaki, M.; Motoki, S.

10.1101/2019.12.12.874925 — biophysics — Posted on 2019-12-13

1703 Stochastic bacterial population dynamics prevent the emergence of antibiotic resistance from single cells

Alexander, H. K.; MacLean, C.

10.1101/458547 — microbiology — Posted on 2019-12-13

1704 Millet-based supplement restored microbiota diversity of acute undernourished pigs

Li, X.; Hui, Y.; Ren, J.; Song, Y.; Liu, S.; Che, L.; Peng, X.; Dai, X.

10.1101/2019.12.13.875013 — microbiology — Posted on 2019-12-13

1705 AFM images of open and collapsed states of yeast condensin suggest a scrunching model for DNA loop extrusion

Ryu, J.-K.; Katan, A. J.; van der Sluis, E. O.; Wisse, T.; de Groot, R.; Hearing, C.; Dekker, C.

10.1101/2019.12.13.867358 — biophysics — Posted on 2019-12-13

1706 Oligomerization of the antimalarial drug target PfATP4 is essential for parasite survival

Ramanathan, A. A.; Morrisey, J. M.; Daly, T. M.; Bergman, L. W.; Mather, M. W.; Vaidya, A. B.

10.1101/2019.12.12.874826 — biochemistry — Posted on 2019-12-13

1707 Polyandry is extremely rare in the firefly squid, Watasenia scintillans

Sato, N.; Tsuda, S.-I.; Alam Md, N. E.; Sasanami, T.; Iwata, Y.; Kusama, S.; Inamura, O.; Yoshida, M.-a.; Hirohashi, N.

10.1101/2019.12.13.875062 — ecology — Posted on 2019-12-13

1708 Active Notch Signaling is Required for Arm Regeneration in a Brittle Star

Mashanov, V.; Akiona, J.; Khoury, M.; Ferrier, J.; Reid, R.; Machado, D. J.; Zueva, O.; Janies, D.

10.1101/2019.12.13.875401 — developmental biology — Posted on 2019-12-13

1709 Spatial mapping of cell types by integration of transcriptomics data

Andersson, A.; Bergenstråhle, J.; Asp, M.; Navarro, J. F.; Bergenstrahle, L.; Jurek, A.; Lundeberg, J.

10.1101/2019.12.13.874495 — bioinformatics — Posted on 2019-12-13

1710 Challenged Immune System Improves Cognitive-Behavioral Responses In Homeostasis And Recovers Malaria-Induced Cognitive Impairment In Mice

de Sousa Vieira, L. P.; Ribeiro-Gomes, F. L.; Almeida, R. F.; e Souza, T. M.; Werneck, G.; Souza, D. O.; Daniel-Ribeiro, C. T.

10.1101/2019.12.13.874420 — animal behavior and cognition — Posted on 2019-12-13

1711 M-TRACK: a platform for live cell multiplex imaging reveals cell phenotypic transition dynamics inherently missing in snapshot data

Wang, W.; Douglas, D. L.; Zhang, J.; Chen, Y.-J.; Cheng, Y.-Y.; Kumari, S.; Enuameh, M. S.; Dai, Y.; Wallace, C. T.; Watkins, S. C.; Shu, W.; Xing, J.

10.1101/2019.12.12.874248 — systems biology — Posted on 2019-12-13

1712 Experimentally engineered mutations in a ubiquitin hydrolase, UBP-1, modulate in vivo resistance to artemisinin and chloroquine in Plasmodium berghei.

Simwela, N. V.; Hughes, K. R.; Roberts, A. B.; Rennie, M. T.; Barrett, M. P.; Waters, A. P.

10.1101/2019.12.12.874990 — microbiology — Posted on 2019-12-13

1713 Delving below the species level to characterize the ecological diversity within the global virome: An exploration of West Nile Virus

Kong, T.; Mei, K.; Wang, A.; Krizanc, D.; Cohan, F. M.

10.1101/2019.12.12.874214 — microbiology — Posted on 2019-12-13

1714 ASTRAL-Pro: quartet-based species tree inference despite paralogy

Zhang, C.; Scornavacca, C.; Molloy, E.; Mirarab, S.

10.1101/2019.12.12.874727 — bioinformatics — Posted on 2019-12-13

1715 Systems analysis of blood transcriptomes in dementia patients reveals an innate immune response shared across disorders

Nachun, D.; Ramos, E. M.; Karydas, A.; Dokuru, D.; Gao, F.; Yang, Z.; Van Berlo, V.; Sears, R. L.; Kramer, J.; Boxer, A. L.; Rosen, H. H.; Miller, B. L.; Coppola, G.

10.1101/2019.12.13.875112 — bioinformatics — Posted on 2019-12-13

1716 BZIP Transcription Factors Modulate DNA Supercoiling Transitions

Hörberg, J.; Reymer, A.

10.1101/2019.12.13.875146 — biochemistry — Posted on 2019-12-13

1717 Boron alters carboxyl group binding capacity and Al transport pathway to relieve Al toxicity

Yan, L.; Riaz, M.; Liu, J.; Liu, Y.; Zeng, Y.; Jiang, C.

10.1101/2019.12.12.874412 — physiology — Posted on 2019-12-13

1718 YbeY is required for ribosome small subunit assembly and tRNA processing in human mitochondria

D'Souza, A. R.; Van Haute, L.; Powell, C. A.; Rebelo- Guiomar, P.; Rorbach, J.; Minczuk, M.

10.1101/2019.12.12.874305 — molecular biology — Posted on 2019-12-13

1719 Polinton-like viruses and virophages are widespread in aquatic ecosystems

Bellas, C. M.; Sommaruga, R.

10.1101/2019.12.13.875310 — microbiology — Posted on 2019-12-13

1720 Heme induces innate immunity memory

Jentho, E.; Novakovic, B.; Ruiz-Moreno, C. C.; Kourtzelis, I.; Martins, R.; Chavakis, T.; Soares, M. P.; Kalafati, L.; Guerra, J.; Roestel, F.; Bohm, P.; Godmann, M.; Grinenko, T.; Eugster, A.; Beretta, M.; Joosten, L. A.; Netea, M. G.; Stunnenberg, H. G.; Bauer, M.; Weis, S.

10.1101/2019.12.12.874578 — immunology — Posted on 2019-12-13

1721 Drebrin-like protein regulates body bending of C. elegans via suppression of NCA cationleak channels

Butkevich, E.; Weist, P.; Härtter, D.; Klopfenstein, D. R.; Garces, R.; Schmidt, C. F.

10.1101/2019.12.12.874289 — genetics — Posted on 2019-12-13

1722 Novel intramolecular base-pairing of the U8 snoRNA underlies a Mendelian form of cerebral small vessel disease

Badrock, A. P.; Uggenti, C.; Wacheul, L.; Crilly, S.; Jenkinson, E. M.; Rice, G. I.; Kasher, P. R.; Lafontaine, D. L. J.; Crow, Y. J.; O'Keefe, R. T.

10.1101/2019.12.12.874594 — genetics — Posted on 2019-12-13

1723 Dual RNA-seq in an aphid parasitoid reveals plastic and evolved adaptation to symbiont-conferred resistance

Dennis, A. B.; Kaech, H.; Vorburger, C.

10.1101/2019.12.13.875104 — evolutionary biology — Posted on 2019-12-13

1724 Extended synaptotagmin regulates plasma membrane-endoplasmic reticulum contact site structure and lipid transfer function in vivo

Nath, V. R.; Mishra, S.; Basak, B.; Trivedi, D.; Raghu, P.

10.1101/2019.12.12.874933 — cell biology — Posted on 2019-12-13

1725 Glucose starvation to rapid death of Nrf1, but not Nrf2, deficient hepatoma cells from its fatal defects in the redox metabolism reprogramming

Zhu, Y.-p.; Zheng, Z.; Xiang, X.; Zhang, Y.

10.1101/2019.12.13.875369 — cell biology — Posted on 2019-12-13

1726 3D bioprinting of architected hydrogels from entangled microstrands

Kessel, B.; Lee, M.; Bonato, A.; Tinguely, Y.; Tosoratti, E.; Zenobi-Wong, M.

10.1101/2019.12.13.870220 — bioengineering — Posted on 2019-12-13

1727 Intracellular Energy Variability Modulates Cellular Decision-Making Capacity

Kerr, R.; Jabbari, S.; Johnston, I. G.

10.1101/2019.12.13.875427 — systems biology — Posted on 2019-12-13

1728 Retinal Plasticity: Functional Recovery after Bipolar Cell Loss in the Oxygen Induced Retinopathy Model

Mitton, K. p.; Deshpande, M.; Wong, S. C.; Guzman, A. E.; Cheng, M.; Dailey, W. A.; Schunemann, R.; Trese, M.; Drenser, K. A.

10.1101/2019.12.12.874271 — neuroscience — Posted on 2019-12-13

1729 Circuit and synaptic organization of forebrain-to-midbrain pathways that promote and suppress vocalization

Michael, V.; Tschida, K.; Goffinet, J.; Pearson, J.; Wang, F.; Mooney, R.

10.1101/2019.12.12.874354 — neuroscience — Posted on 2019-12-13

1730 Phase of Firing Coding of Learning Variables across Prefrontal Cortex, Anterior Cingulate Cortex and Striatum during Feature Learning

Voloh, B.; Oemisch, M.; Womelsdorf, T.

10.1101/2019.12.12.874859 — neuroscience — Posted on 2019-12-13

1731 Molybdate to prevent the formation of sulfide during the process of biogas production

Tenti, P.; Roman, S.; Storelli, N.

10.1101/2019.12.12.874164 — microbiology — Posted on 2019-12-13

1732 Impact of temperature on Legionella pneumophila, its protozoan host cells, and the microbial diversity of the biofilm community of a pilot cooling tower

Torres Paniagua, A.; Paranjape, K.; Hu, M.; Bedard, E.; Faucher, S. P.

10.1101/2019.12.12.874149 — microbiology — Posted on 2019-12-13

1733 mtDNA-based reconstructions of change in effective population sizes of Holarctic birds do not agree with their reconstructed range sizes based on paleoclimates

Miller, E. F.; Green, R. E.; Balmford, A.; Beyer, R.; Somveille, M.; Leonardi, M.; Amos, W.; Manica, A.

10.1101/2019.12.13.870410 — evolutionary biology — Posted on 2019-12-13

1734 Assembly of a young vertebrate Y chromosome reveals convergent signatures of sex chromosome evolution

Peichel, C. L.; McCann, S. R.; Ross, J. A.; Naftaly, A. F. S.; Urton, J. R.; Cech, J. N.; Grimwood, J.; Schmutz, J.; Myers, R. M.; Kingsley, D. M.; White, M. A.

10.1101/2019.12.12.874701 — evolutionary biology — Posted on 2019-12-13

1735 PREDATION CAPACITY OF SOIL-DWELLING PREDATORY MITES ON TWO GROUND BEETLE IMMATURE STAGES: A BIOLOGICAL CONTROL PERSPECTIVE FOR TWO MAJOR MAIZE PESTS.

Pasquier, A.; Andrieux, T.; Vercken, E.; Ferrero, M.

10.1101/2019.12.13.862466 — ecology — Posted on 2019-12-13

1736 Sleep-drive reprograms clock neuronal identity through CREB-binding protein induced PDFR expression

Klose, M. K.; Shaw, P.

10.1101/2019.12.12.874628 — cell biology — Posted on 2019-12-13

1737 The mitotic crosslinking protein PRC1 acts as a mechanical dashpot to resist microtubule sliding

Gaska, I.; Armstrong, M.; Alfieri, A.; Forth, S.

10.1101/2019.12.12.874529 — biophysics — Posted on 2019-12-13

1738 A comprehensive study of Phospholipid fatty acid rearrangements in the early onset of the metabolic syndrome: correlations to organ dysfunction.

Bacle, A.; Kadri, L.; Khoury, S.; Ferru-Clement, R.; Faivre, J.-F.; Cognard, C.; Bescond, J.; Krzesiak, A.; Contzler, H.; Delpech, N.; Colas, J.; Vandebrouck, C.; Sebille, S.; Ferreira, T.

10.1101/2019.12.13.875096 — biochemistry — Posted on 2019-12-13

1739 Delicate balances in cancer chemotherapy: modeling immune recruitment and emergence of systemic drug resistance

Tran, A. P.; Al-Radhawi, M. A.; Kareva, I.; Wu, J.; Waxman, D. J.; Sontag, E. D.

10.1101/2019.12.12.874891 — systems biology — Posted on 2019-12-13

1740 HUMANS USE A LOCAL CODE FOR TACTILE PERCEPTION

Bhattacharjee, A.; Braun, C.; Schwarz, C.

10.1101/2019.12.12.874206 — neuroscience — Posted on 2019-12-13

1741 Perceptual modulation of parietal activity during urgent saccadic choices

Seideman, J. A.; Salinas, E.; Stanford, T. R.

10.1101/2019.12.12.874313 — neuroscience — Posted on 2019-12-13

1742 TDP-43 dysfunction restricts dendritic complexity by inhibiting CREB activation and altering gene expression

Herzog, J. J.; Deshpande, M.; Xu, W.; Rahman, R.; Suib, H.; Rosbash, M.; Rodal, A. A.; Paradis, S.

10.1101/2019.12.12.874735 — neuroscience — Posted on 2019-12-13

1743 YBEY is an essential biogenesis factor for mitochondrial ribosomes

Summer, S.; Smirnova, A.; Gabriele, A.; Toth, U.; Mandela, F.; Foerstner, K. U.; Kuhn, L.; Chicher, J.; Hammann, P.; Mitulovic, G.; Entelis, N.; Tarassov, I.; Rossmanith, W.; Smirnov, A.

10.1101/2019.12.13.874362 — molecular biology — Posted on 2019-12-13

1744 The spread of chloramphenicol-resistant Neisseria meningitidis in Southeast Asia

Batty, E. M.; Cusack, T.-P.; Thaipadungpanit, J.; Watthanaworawit, W.; Carrara, V.; Sihalath, S.; Hopkins, J.; Soeng, S.; Ling, C.; Turner, P.; Dance, D. A. B.

10.1101/2019.12.13.872499 — microbiology — Posted on 2019-12-13

1745 Surprising variation in the outcome of two malaria genetic crosses using humanized mice: implications for genetic mapping and malaria biology

10.1101/2019.12.13.871830 — genetics — Posted on 2019-12-13

1746 Cavefish Increase Red Blood Cell Development and Reprogram Metabolism as Adaptations to Environmental Hypoxia

van der Weele, C. M.; Jeffery, W.

10.1101/2019.12.12.874230 — evolutionary biology — Posted on 2019-12-13

1747 Chromatin remodeling in bovine embryos indicates species-specific regulation of genome activation

Halstead, M. M.; Ma, X.; Schultz, R. M.; Ross, P. J.

10.1101/2019.12.12.874479 — developmental biology — Posted on 2019-12-13

1748 Single cell lineage dynamics of the endosymbiotic cell type in a soft coral Xenia species

Hu, M.; Zheng, X.; Fan, C.-M.; Zheng, Y.

10.1101/2019.12.12.874602 — cell biology — Posted on 2019-12-13

1749 Integration of immunome with disease gene network reveals pleiotropy and novel drug repurposing targets

Devaprasad, A.; Radstake, T. R.; Pandit, A.

10.1101/2019.12.12.874321 — bioinformatics — Posted on 2019-12-13

1750 Metabolic switching is impaired by aging and facilitated by ketosis independent of glycogen

Hernandez, A. R.; Truckenbrod, L. M.; Federico, Q. P.; Campos, K. T.; Moon, B. M.; Ferekides, N.; Hoppe, M.; D'Agostino, D.; Burke, S. N.

10.1101/2019.12.12.874297 — biochemistry — Posted on 2019-12-13

1751 Impaired cholesterol metabolism in the mice model of cystic fibrosis. A vicious circle?

Amato, F.; Castaldo, A.; Castaldo, G.; Cernera, G.; Corso, G.; Ferrari, E.; Gelzo, M.; Monzani, R.; Villella, V. R.; Raia, V.

10.1101/2019.12.13.875336 — biochemistry — Posted on 2019-12-13

1752 Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis.

Ried, M. K.; Wild, R.; Zhu, J.; Broger, L.; Harmel, R. K.; Hothorn, L. A.; Fiedler, D.; Hothorn, M.

10.1101/2019.12.13.875393 — plant biology — Posted on 2019-12-13

1753 Boron deficiency-induced root growth inhibition is mediated by BR signal regulation in Arabidopsis

Xu, F.; Zhang, C.; He, M. L.; Wang, S.; Chu, L.; Wang, C.; Yang, N.; Ding, G. D.; Cai, H.; Shi, L.

10.1101/2019.12.12.874222 — physiology — Posted on 2019-12-13

1754 Automatic Detection of Synaptic Partners in a Whole-Brain Drosophila EM Dataset

Buhmann, J.; Sheridan, A.; Gerhard, S.; Krause, R.; Nguyen, T.; Heinrich, L.; Schlegel, P.; Lee, W.-C. A.; Wilson, R.; Saalfeld, S.; Jefferis, G. S. X. E.; Bock, D.; Turaga, S.; Cook, M.; Funke, J.

10.1101/2019.12.12.874172 — neuroscience — Posted on 2019-12-13

1755 A precisely-titratable, variation-suppressed transcriptional controller to enable genetic discovery

Azizoglu, A.; Brent, R.; Fabian, R.

10.1101/2019.12.12.874461 — molecular biology — Posted on 2019-12-13

1756 Network analysis of promoter interactions reveals the hierarchical differences in genome organisation between human pluripotent states

Chovanec, P.; Collier, A.; Krueger, C.; Varnai, C.; Schoenfelder, S.; Corcoran, A.; Rugg-Gunn, P.

10.1101/2019.12.13.875286 — genomics — Posted on 2019-12-13

1757 Natural hybridization reveals incompatible alleles that cause melanoma in swordtail fish

Powell, D. L.; Garcia, M.; Keegan, M.; Reilly, P.; Du, K.; Diaz-Loyo, A. P.; Banerjee, S.; Blakkan, D.; Reich, D. E.; Andolfatto, P.; Rosenthal, G. G.; Schartl, M.; Schumer, M.

10.1101/2019.12.12.874586 — evolutionary biology — Posted on 2019-12-13

1758 The evolutionary origins of the tumor necrosis factor receptor family - cell death or differentiation?

Steichele, M.; Bottger, A.

10.1101/2019.12.13.875351 — developmental biology — Posted on 2019-12-13

1759 An evolution-based method of epistasis measurement: theory and application to influenza

Pedruzzi, G.; Rouzine, I. M.

10.1101/2019.12.11.873307 — genetics — Posted on 2019-12-13

1760 Identification of 20 novel loci associated to ischemic stroke. Epigenome-Wide Association Study

Soriano Tarraga, C.; Lazcano, U.; Giralt-Steinhauer, E.; Avellaneda-Gomez, C.; Ois, A.; Rodriguez-Campello, A.; Cuadrado-Godia, E.; Gomez-Gonzalez, A.; Fernandez-Sanles, A.; Elosua, R.; Fernandez-Cadenas, I.; Cullell, N.; Montaner, J.; Moran, S.; Esteller, M.; Jimenez-Conde, J.; Roquer, J.

10.1101/2019.12.11.872945 — genetics — Posted on 2019-12-13

1761 Evolutionary stasis of an RNA virus indicates arbovirus re-emergence triggered by accidental release

Pascall, D. J.; Nomikou, K.; Breard, E.; Zientara, S.; da Silva Filipe, A.; Hoffmann, B.; Jacquot, M.; Singer, J. B.; De Clercq, K.; Botner, A.; Sailleau, C.; Viarouge, C.; Batten, C.; Puggioni, G.; Ligios, C.; Savini, G.; van Rijn, P. A.; Mertens, P. P.; Biek, R.; Palmarini, M.

10.1101/2019.12.11.872705 — evolutionary biology — Posted on 2019-12-13

1762 A compartment size dependent selective threshold limits mutation accumulation in hierarchical tissues

Grajzel, D.; Derenyi, I.; Szollosi, G. J.

10.1101/719575 — evolutionary biology — Posted on 2019-12-13

1763 The importance of Indigenous Peoples' lands for the conservation of terrestrial vertebrates

O'Bryan, C. J.; Garnett, S. T.; Fa, J. E.; Leiper, I.; Rehbein, J.; Fernandez-Llamazares, A.; Jonas, H. D.; Brondizio, E. S.; Burgess, N. D.; Robinson, C. J.; Zander, K. K.; Venter, O.; Watson, J. E. M.

10.1101/2019.12.11.873695 — ecology — Posted on 2019-12-13

1764 Track-Control, an automatic video-based real-time closed-loop behavioral control toolbox

Zhang, G.-W.; Shen, L.; Li, Z.; Tao, H. W.; Zhang, L. I.

10.1101/2019.12.11.873372 — animal behavior and cognition — Posted on 2019-12-13

1765 Effective buprenorphine use and tapering strategies: Endorsements and insights by people in recovery from opioid use disorder on a Reddit forum

Graves, R. L.; Sarker, A.; Al-Garadi, M. A.; Yang, Y.-c.; Love, J. S.; O'Connor, K.; Gonzalez-Hernandez, G.; Perrone, J.

10.1101/871608 — pharmacology and toxicology — Posted on 2019-12-13

1766 Unveiling the dimer/monomer propensities of Smad MH1-DNA complexes

Ruiz, L.; Kaczmarska, Z.; Gomes, T.; Aragon, E.; Torner, C.; Freier, R.; Baginski, B.; Martin-Malpartida, P.; de Martin Garrido, N.; Marquez, J. A.; Cordeiro, T. N.; Pluta, R.; Macias, M. J.

10.1101/833319 — molecular biology — Posted on 2019-12-13

1767 Widespread interaction between ADAR1 and transcriptional byproducts

Wu, C. S.; Tang, S. J.; Tan, H. K.; Hung, L.-Y.; Teo, W. W.; Li, J.; An, O.; Tan, K. T.; Zhou, Q.; Chen, L.; Tenen, D. G.; Yang, H.

10.1101/870782 — genomics — Posted on 2019-12-13

1768 The Onset of Evolutionary Stalling and the Limit on the Power of Natural Selection to Improve a Cellular Module

Venkataram, S.; Monasky, R.; Sikaroodi, S. H.; Kryazhimskiy, S.; Kacar, B.

10.1101/850644 — evolutionary biology — Posted on 2019-12-13

1769 Nonlinear convergence preserves information

Gutierrez, G. J.; Rieke, F.; Shea-Brown, E.

10.1101/811539 — neuroscience — Posted on 2019-12-13

1770 Effects of gut microbiota perturbation on Th1- and Th2-biased mice following treatment with Vancomycin

Ray, P.; Aich, P.

10.1101/516898 — microbiology — Posted on 2019-12-13

1771 Beyond SNP Heritability: Polygenicity and Discoverability of Phenotypes Estimated with a Univariate Gaussian Mixture Model

Holland, D.; Frei, O.; Desikan, R.; Fan, C.-C.; Shadrin, A. A.; Smeland, O. B.; Sundar, V. S.; Thompson, P.; Andreassen, O. A.; Dale, A. M.

10.1101/133132 — genomics — Posted on 2019-12-13

1772 Reconstruction of networks with direct and indirect genetic effects

Kruijer, W.; Behrouzi, P.; Bustos Korts, D.; Rodriguez-Alvarez, M. X.; Mahmoudi, S. M.; Yandell, B.; Wit, E.; Van Eeuwijk, F.

10.1101/646208 — genetics — Posted on 2019-12-13

1773 ProtCID: A data resource for structural information on protein interactions

Xu, Q.; Dunbrack, R. L.

10.1101/579862 — bioinformatics — Posted on 2019-12-13

1774 Methods detecting rhythmic gene expression are biologically relevant only for strong signal.

Laloum, D.; Robinson-Rechavi, M.

10.1101/730937 — bioinformatics — Posted on 2019-12-13

1775 Cusp-artifacts in high order superresolution optical fluctuation imaging

Yi, X.; Weiss, S.

10.1101/545574 — bioengineering — Posted on 2019-12-13

1776 Landscape structured by physical settings and benthic polychaete and avifauna habitat uses in a mangrove-vegetated estuary

Shih, S.-S.; Ding, T.-S.; Chen, C.-P.; Huang, S.-C.; Hsieh, H.-L.

10.1101/2019.12.12.874008 — ecology — Posted on 2019-12-12

1777 Cytological abnormalities and pollen abortion in interspecific hybrids of Nicotiana

Liao, J.; Chen, Z.; Pan, Z.; Niu, Y.; Suo, W.; Wei, X.; Zhen, Y.; Lv, L.; Ma, W.; Chen, S.

10.1101/2019.12.12.873968 — developmental biology — Posted on 2019-12-12

1778 Influence of age and gender on taste function of healthy subjects

Wang, J.-J.; Liang, K.-L.; Lin, W.-J.; Chen, C.-Y.; Jiang, R.-S.

10.1101/2019.12.12.873976 — physiology — Posted on 2019-12-12

1779 Computational characteristics of the striatal dopamine system described by reinforcement learning with fast generalization

Fujita, Y.; Yagishita, S.; Kasai, H.; Ishii, S.

10.1101/2019.12.12.873950 — neuroscience — Posted on 2019-12-12

1780 Synesthesia does not help to recover perceptual dominance following flash suppression

Jimena Arias, D.; Saint-Amour, D.

10.1101/2019.12.12.873992 — neuroscience — Posted on 2019-12-12

1781 Filoviruses Can Efficiently Infect Human Neuron-Like Cells Without Genetic Adaptation

McAuley, A.; Tachedjian, M.; Marsh, G. A.

10.1101/2019.12.12.874016 — microbiology — Posted on 2019-12-12

1782 Seasonal Variation in the Internet Searches for Cancer Recurrence: An Infodemiological Study

Wang, F.; Lou, q. X.; Hu, t. D.; Zhang, M.; Xie, Q.; Zou, Y.

10.1101/2019.12.12.873984 — cancer biology — Posted on 2019-12-12

1783 High Capacity poly(2-oxazoline) formulation of TLR 7/8 agonist extends survival in a chemo-insensitive, metastatic model of Lung Adenocarcinoma

Vinod, N.; Hwang, D.; Azam, S. H.; Van Swearingen, A. E. D.; Wayne, E.; Fussell, S. C.; Sokolsky-Papkov, M.; Pecot, C. V.; Kabanov, A. V.

10.1101/2019.12.12.874198 — pharmacology and toxicology — Posted on 2019-12-12

1784 Cell type specific gene expression profiling reveals a role for the complement component C3A in neutrophil migration to tissue damage

Houseright, R. A.; Rosowski, E. E.; Lam, P. Y.; Tauzin, S. J.; Mulvaney, O.; Dewey, C. N.; Bennin, D.; Huttenlocher, A.

10.1101/2019.12.12.874511 — immunology — Posted on 2019-12-12

1785 Mechanism of action of rigosertib does not involve tubulin binding

Baker, S. J.; Cosenza, S. C.; Athuluri-Divakar, S.; Reddy, M. V. R.; Vasquez-Del Carpio, R.; Jain, R.; Aggarwal, A. K.; Reddy, E. P.

10.1101/2019.12.12.874719 — cancer biology — Posted on 2019-12-12

1786 Towards establishing internal validity for correlated gene expression measures in imaging genomics of functional networks: why distance corrections and external face validity alone fall short. Reply to "Distance is not everything in imaging genomics of functional networks: reply to a commentary on Correlated gene expression supports synchronous activity in brain networks"

Pantazatos, S.; Schmidt, M.

10.1101/2019.12.09.869412 — neuroscience — Posted on 2019-12-12

1787 A Holistic Analysis of the Intestinal Stem Cell Niche Network

Hansen, D. M.; Meneses Giles, P. I.; He, X. C.; Chen, S.; Paulson, A.; Dekaney, C. M.; Wang, J.; Hu, D.; Venkatraman, A.; Kim, W.; Kaddis, J.; Olack, B. J.; Dunn, J. C. Y.; Kuo, C.; Henning, S.; Hanash, A. M.; Houchen, C. W.; Lynch, J.; Martin, M. G.; Niland, J. C.; Stelzner, M.; Wong, M.; Wang, T. C.; Yu, J.; Yan, K.; Li, L.

10.1101/2019.12.12.871756 — cell biology — Posted on 2019-12-12

1788 Evaluating the efficacy of enzalutamide and the development of resistance in a preclinical mouse model of type-I endometrial carcinoma

Koivisto, C. S.; Parrish, M.; Bonala, S. B.; Ngoi, S.; Torres, A.; Gallagher, J.; Sanchez-Hodge, R.; Zeinner, V.; Nahhas, G. J.; Liu, B.; Cohn, D. E.; Backes, F. J.; Goodfellow, P. J.; Chamberlin, H. M.; Leone, G.

10.1101/2019.12.06.868182 — cancer biology — Posted on 2019-12-12

1789 Context-specific control of the neural dynamics of temporal attention by the human cerebellum

Breska, A.; Ivry, R. B.

10.1101/2019.12.12.874677 — neuroscience — Posted on 2019-12-12

1790 Genetic characterization of Streptococcus equi subspecies zooepidemicus associated with high swine mortality in United States

Chen, X.; Resende-De-Macedo, N.; Sitthicharoenchai, P.; Sahin, O.; Burrough, E.; Clavijo, M.; Derscheid, R.; Schwartz, K.; Lantz, K.; Robbe-Austerman, S.; Main, R.; Li, G.

10.1101/2019.12.12.874644 — microbiology — Posted on 2019-12-12

1791 A fast and simple method for detecting identity by descent segments in large-scale data

Zhou, Y.; Browning, S.; Browning, B. L.

10.1101/2019.12.12.874685 — bioinformatics — Posted on 2019-12-12

1792 Xrn1p Acts at Multiple Steps in the Budding-Yeast RNAi Pathway to Enhance the Efficiency of Silencing

Getz, M. A.; Weinberg, D. E.; Drinnenberg, I. A.; Fink, G. R.; Bartel, D. P.

10.1101/2019.12.12.873604 — molecular biology — Posted on 2019-12-12

1793 Extracellular DNA promotes efficient extracellular electron transfer by pyocyanin in Pseudomonas aeruginosa biofilms

Saunders, S. H.; Tse, E. C. M.; Yates, M. D.; Jimenez Otero, F.; Trammell, S. A.; Stemp, E. D. A.; Barton, J. K.; Tender, L. M.; Newman, D. K.

10.1101/2019.12.12.872085 — microbiology — Posted on 2019-12-12

1794 Causal role of L-glutamine in sickle cell disease painful crises: a Mendelian randomization analysis

Ilboudo, M. Y. T.; Garrett, M. E.; Bartolucci, P.; Brugnara, C.; Clish, C.; Hirschhorn, J.; Galacteros, F.; Ashley-Koch, A.; Telen, M.; Lettre, G.

10.1101/872358 — genetics — Posted on 2019-12-12

1795 Cleft lip and cleft palate (CL/P) in Esrp1 KO mice is associated with alterations in Wnt signaling and epithelial-mesenchymal crosstalk

Carstens, R. P.; Lee, S.; Sears, M. J.; Li, H.; Salhab, I.; Krebs, P.; Zhang, Z.; Xing, Y.; Nah, H.-D.; Williams, T.

10.1101/2019.12.12.874636 — developmental biology — Posted on 2019-12-12

1796 A spatio-temporal mathematical model for the dynamics of paclitaxel in cell monolayers.

Proudfoot, I.; Epemolu, O.; Vallardi, G.; Ptashnyk, M.; Saurin, A. T.; Murray, P. J.; Shishikura, Y.

10.1101/2019.12.12.874032 — cancer biology — Posted on 2019-12-12

1797 Bacterial Major Vault Protein homologs shed new light on origins of the enigmatic organelle

Sokolskyi, T.

10.1101/872010 — evolutionary biology — Posted on 2019-12-12

1798 Integrin-alpha-6+ Stem Cells (ISCs) are responsible for whole body regeneration in an invertebrate chordate

Kassmer, S. H.; Langenbacher, A. D.; De Tomaso, A. W.

10.1101/647578 — developmental biology — Posted on 2019-12-12

1799 DNA origami nanostructures as a tool for the targeted destruction of bacteria

Mela, I.; Vallejo-Ramirez, P. P.; Makarchuk, S.; Christie, G.; Bailey, D. M. D.; Henderson, R. M.; Sugiyama, H.; Endo, M.; Kaminski, C. F.

10.1101/837252 — bioengineering — Posted on 2019-12-12

1800 Development and Optimisation of a Defined High Cell Density Yeast Medium

Roberts, T. M.; Kaltenbach, H.-M.; Fabian, R.

10.1101/846006 — microbiology — Posted on 2019-12-12

1801 Serum proteomics expands on identifying more high-affinity antibodies in immunized rabbits than deep B-cell repertoire sequencing alone

Bonissone, S. R.; Lima, T.; Harris, K.; Davison, L.; Avanzino, B.; Trinklein, N.; Castellana, N.; Patel, A.

10.1101/833871 — immunology — Posted on 2019-12-12

1802 Objects seen as scenes: neural circuitry for attending whole or parts

Valdes-Sosa, M. J.; Ontivero-Ortega, M.; Iglesias-Fuster, J.; Lage-Castellanos, A.; Gong, J.; Luo, C.; Castro-Laguardia, A. M.; Bobes-Leon, M. A.; Marinazzo, D.; Yao, D.

10.1101/771899 — neuroscience — Posted on 2019-12-12

1803 Development and Optimisation of a Defined High Cell Density Yeast Medium

Roberts, T. M.; Kaltenbach, H.-M.; Fabian, R.

10.1101/846006 — microbiology — Posted on 2019-12-12

1804 Evaluating and improving heritability models using summary statistics

Speed, D.; Holmes, J. B.; Balding, D. J.

10.1101/736496 — genetics — Posted on 2019-12-12

1805 Endocycles support tissue growth and regeneration of the adult Drosophila accessory gland

Box, A. M.; Church, S. J.; Hayes, D.; Nandakumar, S.; Taichman, R. S.; Buttitta, L.

10.1101/719013 — developmental biology — Posted on 2019-12-12

1806 Sex and pedagogy influences in physics learning-related reorganization of brain activity

Bartley, J. E.; Riedel, M. C.; Salo, T.; Bottenhorn, K. L.; Boeving, E. R.; Laird, R. W.; Sutherland, M. T.; Pruden, S. M.; Brewe, E.; Laird, A. R.

10.1101/791301 — neuroscience — Posted on 2019-12-12

1807 AnthOligo: Automating the design of oligonucleotides for capture/enrichment technologies

Jayaraman, P.; Mosbruger, T.; Hu, T.; Tairis, N. G.; Wu, C.; Clark, P. M.; D'Arcy, M.; Ferriola, D.; Mackiewicz, K.; Gai, X.; Monos, D. S.; Sarmady, M.

10.1101/2019.12.12.873497 — bioinformatics — Posted on 2019-12-12

1808 Male accessory gland factors increased sex pheromone titres in the glands of Spodoptera litura female moths by inhibiting calling behavior

Xu, J.; Shi, M.-R.; Fu, D.-Y.; Yu, H.; Chen, P.; Ye, H.

10.1101/872150 — zoology — Posted on 2019-12-12

1809 Consumption of a Western-style diet modulates the response of the murine gut microbiome to ciprofloxacin

Cabral, D. J.; Wurster, J. I.; Korry, B. J.; Penumutchu, S.; Belenky, P.

10.1101/780049 — microbiology — Posted on 2019-12-12

1810 Targeting a Long Non-Coding RNA splicing by novel candidate drug ABX464 to produce the anti-inflammatory microRNA miR-124

Manchon, L.; Vautrin, A.; Garcel, A.; Campos, N.; Tazi, J.

10.1101/2019.12.11.871335 — immunology — Posted on 2019-12-12

1811 Bacterial Major Vault Protein homologs shed new light on origins of the enigmatic organelle

Sokolskyi, T.

10.1101/872010 — evolutionary biology — Posted on 2019-12-12

1812 Mitigating Local Over-fitting During Single Particle Reconstruction with SIDESPLITTER

Ramlaul, K.; Palmer, C. M.; Aylett, C. H. S.

10.1101/2019.12.12.874081 — biophysics — Posted on 2019-12-12

1813 Prediction of 8-state protein secondary structures by 1D-Inception and BD-LSTM

Ratul, M. A. R.; Turcotte, M.; Mozaffari, M. H.; Lee, W.

10.1101/871921 — bioinformatics — Posted on 2019-12-12

1814 Element content and distribution has limited, tolerance metric dependent, impact on salinity tolerance in cultivated sunflower (Helianthus annuus)

Temme, A. A.; Burns, V. A.; Donovan, L. A.

10.1101/2019.12.11.872929 — plant biology — Posted on 2019-12-12

1815 Region-specific and dose-specific effects of chronic haloperidol exposure on Ro15-4513 GABA-A receptor binding sites in the rat brain

Peris-Yague, A.; Kiemes, A.; Cash, D.; Cotel, M.-C.; Singh, N.; Vernon, A. C.; Modinos, G.

10.1101/869941 — neuroscience — Posted on 2019-12-12

1816 Deficiency of Norepinephrine Transmission In Brain Contributed To Seizure-Induced Respiratory Arrest In the DBA/1 Mouse SUDEP Model

Shen, Y.; MA, H.; Lu, H.; Zhao, H.; Sun, J.; Cheng, Y.; Shen, Y.; Zhou, Y. D.; Zhang, H.

10.1101/865691 — neuroscience — Posted on 2019-12-12

1817 Characteristics of a novel NMR-based metabolomics platform for dogs

Ottka, C.; Vapalahti, K.; Puurunen, J.; Vahtera, L.; Lohi, H.

10.1101/871285 — molecular biology — Posted on 2019-12-12

1818 Direct antiviral activity of interferon stimulated genes is responsible for resistance to paramyxoviruses in ISG15-deficient cells

Holthaus, D.; Vasou, A.; Bamford, C. G.; Andrejeva, J.; Paulus, C.; Randall, R. E.; McLauchlan, J.; Hughes, D. J.

10.1101/2019.12.12.873919 — immunology — Posted on 2019-12-12

1819 Widespread interaction between ADAR1 and transcriptional byproducts

Wu, C. S.; Tang, S. J.; Tan, H. K.; Hung, L.-Y.; Teo, W. W.; Li, J.; An, O.; Tan, K. T.; Zhou, Q.; Chen, L.; Tenen, D. G.; Yang, H.

10.1101/870782 — genomics — Posted on 2019-12-12

1820 Localizing components of shared transethnic genetic architecture of complex traits from GWAS summary data

Shi, H.; Burch, K. S.; Johnson, R.; Freund, M. K.; Kichaev, G.; Mancuso, N.; Manuel, A. M.; Dong, N.; Pasaniuc, B.

10.1101/858431 — genomics — Posted on 2019-12-12

1821 Introgression in Brownea suggests that reticulate evolution contributes to Amazonian tree diversity

Schley, R. J.; Pennington, T.; Perez-Escobar, O. A.; Helmstetter, A. J.; de la Estrella, M.; Larridon, I.; Sabino Kikuchi, I. A. B.; Barraclough, T. G.; Forest, F.; Klitgaard, B. B.

10.1101/2019.12.12.873927 — evolutionary biology — Posted on 2019-12-12

1822 Intra-Species Differences in Population Size shape Life History and Genome Evolution

Willemsen, D.; Cui, R.; Reichard, M.; Valenzano, D. R.

10.1101/852368 — evolutionary biology — Posted on 2019-12-12

1823 A novel system for maintaining Varroa destructor mites on artificial diets and its application for studying mites as a vector for honey bee viruses.

Posada-Florez, F.; Ryabov, E. V.; Heerman, M. C.; Chen, Y.; Evans, J. D.; Cook, S. C.; Sonenshine, D. E.

10.1101/2019.12.12.874107 — zoology — Posted on 2019-12-12

1824 Tubular STAT3 limits renal inflammation in autosomal dominant polycystic kidney disease

Viau, A.; Baziz, M.; Aka, A.; Nguyen, C.; Kuehn, E. W.; Terzi, F.; Bienaime, F.

10.1101/2019.12.12.873901 — pathology — Posted on 2019-12-12

1825 An improved ATP FRET sensor for yeast shows heterogeneity during nutrient transitions

Botman, D.; van Heerden, J. H.; Teusink, B.

10.1101/2019.12.12.874115 — molecular biology — Posted on 2019-12-12

1826 The Pseudomonas aeruginosa lectin LecB causes integrin internalization to facilitate crawling of bacteria underneath host cells

Thuenauer, R.; Landi, A.; Trefzer, A.; Altmann, S.; Wehrum, S.; Eierhoff, T.; Diedrich, B.; Dengjel, J.; Nystroem, A.; Imberty, A.; Roemer, W.

10.1101/2019.12.12.872739 — microbiology — Posted on 2019-12-12

1827 GtcA is required for LTA glycosylation in Listeria monocytogenes serovar 1/2a and Bacillus subtilis

Rismondo, J.; Haddad, T. F.; Shen, Y.; Loessner, M.; Grundling, A.

10.1101/2019.12.12.873851 — microbiology — Posted on 2019-12-12

1828 Bagworm decorations are an anti-predatory structure

Khan, M. K.

10.1101/2019.12.12.873893 — evolutionary biology — Posted on 2019-12-12

1829 Global Bee Decline

Zattara, E. E.; Aizen, M. A.

10.1101/869784 — ecology — Posted on 2019-12-12

1830 Polyploidy in the adult Drosophila brain

Nandakumar, S.; Grushko, O.; Buttitta, L.

10.1101/852723 — developmental biology — Posted on 2019-12-12

1831 The Arabidopsis condensin CAP-D subunits arrange interphase chromatin

Municio, C.; Antosz, W.; Grasser, K. D.; Kornobis, E.; Van Bel, M.; Eguinoa, I.; Coppens, F.; Braeutigam, A.; Lermontova, I.; Bruckmann, A.; Houben, A.; Schubert, V.

10.1101/2019.12.12.873885 — cell biology — Posted on 2019-12-12

1832 FLASH irradiation enhances the therapeutic index of abdominal radiotherapy in mice

Levy, K.; Natarajan, S.; Wang, J.; Chow, S.; Eggold, J.; Loo, P.; Manjappa, R.; Lartey, F. M.; Schüler, E.; Skinner, L.; Rafat, M.; Ko, R.; Kim, A.; Al Rawi, D.; von Eyben, R.; Dorigo, O.; Casey, K. M.; Graves, E. E.; Bush, K.; Yu, A. S.; Koong, A. C.; Maxim, P. G.; Loo, B. W.; Rankin, E. B.

10.1101/2019.12.12.873414 — cancer biology — Posted on 2019-12-12

1833 The accidental ally: Nucleosomal barriers can accelerate cohesin mediated loop formation in chromatin

Maji, A.; Padinhateeri, R.; Mitra, M. K.

10.1101/861161 — biophysics — Posted on 2019-12-12

1834 Characterization of the adaptation to visuomotor rotations in the muscle synergies space

Severini, G.; Zych, M.

10.1101/2019.12.12.873802 — bioengineering — Posted on 2019-12-12

1835 Model-driven design allows growth of Mycoplasma pneumoniae on serum-free media

Gaspari, E.; Malachowski, A.; Garcia-Morales, L.; Burgos, R.; Serrano, L.; Martins dos Santos, V. A. P.; Suarez-Diez, M.

10.1101/2019.12.12.873117 — systems biology — Posted on 2019-12-12

1836 Cell-free genetic devices confer autonomic and adaptive properties to hydrogels

Whitfield, C. J.; Banks, A. M.; Dura, G.; Love, J.; Fieldsend, J. E.; Fulton, D. A.; Howard, T. P.

10.1101/2019.12.12.872622 — synthetic biology — Posted on 2019-12-12

1837 Emergent honeycomb topology of the leaf spongy mesophyll

Borsuk, A.; Roddy, A.; Theroux-Rancourt, G.; Brodersen, C.

10.1101/852459 — plant biology — Posted on 2019-12-12

1838 The a-isoform of VEGFA165 is a Significantly Stronger Activator of Human Retinal Endothelial Cells compared to the b-isoform

Dailey, W.; Schunemann, R.; Yang, F.; Moore, M.; Knapp, A.; Chen, P.; Deshpande, M.; Metcalf, B.; Tompkins, Q.; Guzman, A. E.; Felisky, J.; Mitton, K. P.

10.1101/2019.12.12.871947 — cell biology — Posted on 2019-12-12

1839 Reprogrammed mRNA translation drives metabolic response to therapeutic targeting of ribosome biogenesis

Kusnadi, E. P.; Trigos, A. S.; Cullinane, C.; Goode, D. L.; Larsson, O. S.; Devlin, J. R.; Chan, K. T.; DeSouza, D. P.; McConville, M. J.; McArthur, G. A.; Thomas, G.; Sanij, E.; Poortinga, G.; Hannan, R. D.; Hannan, K. M.; Kang, J.; Pearson, R. B.

10.1101/847723 — cancer biology — Posted on 2019-12-12

1840 coil: an R package for cytochrome C oxidase I (COI) DNA barcode data cleaning, translation, and error evaluation.

Nugent, C. M.; Elliott, T. A.; Ratnasingham, S.; Adamowicz, S. J.

10.1101/2019.12.12.865014 — bioinformatics — Posted on 2019-12-12

1841 High-fidelity Musculoskeletal Modeling Reveals a Motor Planning Contribution to the Speed-Accuracy Tradeoff

Al Borno, M.; Vyas, S.; Shenoy, K. V.; Delp, S.

10.1101/804088 — neuroscience — Posted on 2019-12-12

1842 Cerebral artery segmentation based on magnetization-prepared two rapid acquisition gradient echo multi-contrast images in 7 Tesla magnetic resonance imaging

Choi, U.-S.; Kawaguchi, H.; Kida, I.

10.1101/2019.12.12.870840 — neuroscience — Posted on 2019-12-12

1843 The interplay of top-down focal attention and the cortical tracking of speech

Lesenfants, D.; Francart, T.

10.1101/813147 — neuroscience — Posted on 2019-12-12

1844 Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes

Gründl, M.; Walz, S.; Hauf, L.; Schwab, M.; Werner, K. M.; Spahr, S.; Ade, C. P.; Gaubatz, S.

10.1101/824755 — molecular biology — Posted on 2019-12-12

1845 Biodegradation of Chlorpyrifos and 3,5,6-trichloro-2-pyridinol (TCP) by Ochrobactrum sp. CPD-03: Insights from genome analysis on organophosphorus pesticidesdegradation, chemotaxis and PGPR activity

Nayak, T.; Panda, A. N.; Adhya, T. K.; Das, B.; Raina, V.

10.1101/2019.12.12.866210 — microbiology — Posted on 2019-12-12

1846 Distinct microbial and immune niches of the human colon

James, K. R.; Gomes, T.; Elmentaite, R.; Kumar, N.; Gulliver, E. L.; King, H. W.; Stares, M. D.; Bareham, B. R.; Ferdinand, J. R.; Petrova, V.; Polanski, K.; Forster, S. C.; Jarvis, L. B.; Suchanek, O.; Howlett, S.; James, L.; Jones, J. L.; Meyer, K. B.; Clatworthy, M. R.; Saeb-Parsy, K.; Lawley, T.; Teichmann, S. A.

10.1101/2019.12.12.871657 — immunology — Posted on 2019-12-12

1847 SCRIBE: a new approach to dropout imputation and batch effects correction for single-cell RNA-seq data

Zhang, Y.; Liang, K.; Liu, M.; Li, Y.; Ge, H.; Zhao, H.

10.1101/793463 — bioinformatics — Posted on 2019-12-12

1848 Live-cell imaging of early events following pollen perception in self-incompatible Arabidopsis thaliana

Rozier, F.; Riglet, L.; Kodera, C.; Bayle, V.; Durand, E.; Gaude, T.; Fobis-Loisy, I.; Schnabel, J.

10.1101/760579 — plant biology — Posted on 2019-12-12

1849 The NALCN channel complex is voltage sensitive and directly modulated by extracellular calcium

Chua, H. C.; Wulf, M.; Weidling, C.; Rasmussen, L. P.; Pless, S. A.

10.1101/740456 — neuroscience — Posted on 2019-12-12

1850 Localization of immunoreactive, dystonia-associated protein torsinA near the Golgi apparatus of cultured rodent astrocytes

Iwabuchi, S.; Kawano, H.; Harata, N. C.

10.1101/2019.12.11.873554 — neuroscience — Posted on 2019-12-12

1851 Sleep homeostasis reflects temporally integrated local cortical neuronal activity

Thomas, C. W.; Guillaumin, M. C. C.; McKillop, L. E.; Achermann, P.; Vyazovskiy, V. V.

10.1101/756270 — neuroscience — Posted on 2019-12-12

1852 A quiescent state following mild sensory arousal in Caenorhabditis elegans is potentiated by stress

McClanahan, P. D.; Dubuque, J. M.; Kontogiorgos-Heintz, D.; Habermeyer, B. F.; Xu, J.; Ma, A.; Raizen, D. M.; Fang-Yen, C.

10.1101/784306 — neuroscience — Posted on 2019-12-12

1853 Ratiometric quorum sensing in bacterial conjugation

Banderas, A.; Carcano, A.; Sia, E.; Li, S.; Lindner, A.

10.1101/2019.12.11.871699 — microbiology — Posted on 2019-12-12

1854 Sustained virome diversity in Antarctic penguins and their ticks: geographical connectedness and no evidence for low pathogen pressure

Wille, M.; Harvey, E.; Shi, M.; Gonzalez-Acuna, D.; Holmes, E. C.; Hurt, A.

10.1101/2019.12.11.873513 — microbiology — Posted on 2019-12-12

1855 Maternal alum-adjuvanted recombinant HIV Env vaccine does not enhance autologous virus neutralization in HIV-infected pregnant women

Hompe, E. D.; Mangold, J. F.; Eudailey, J. A.; Giorgi, E. E.; Kumar, A.; McGuire, E.; Haynes, B. F.; Moody, M. A.; Wright, P. F.; Fouda, G. G.; Gao, F.; Permar, S. R.

10.1101/2019.12.11.873018 — immunology — Posted on 2019-12-12

1856 The transcriptional legacy of developmental stochasticity

Ballouz, S.; Pena, M.; Knight, F. M.; Adams, L.; Gillis, J.

10.1101/2019.12.11.873265 — genomics — Posted on 2019-12-12

1857 Single nucleus multi-omics links human cortical cell regulatory genome diversity to disease risk variants

Luo, C.; Liu, H.; Xie, F.; Armand, E. J.; Siletti, K.; Bakken, T.; Fang, R.; Doyle, W. I.; Hodge, R. D.; Hu, L.; Wang, B.-A.; Zhang, Z.; Preissl, S.; Lee, D.-S.; Zhou, J.; Niu, S.-Y.; Castanon, R.; Bartlett, A.; Rivkin, A.; Wang, X.; Lucero, J.; Nery, J. R.; Davis, D. A.; Mash, D. C.; Dixon, J. R.; Linnarsson, S.; Lein, E.; Behrens, M. M.; Ren, B.; Mukamel, E. A.; Ecker, J. R.

10.1101/2019.12.11.873398 — genomics — Posted on 2019-12-12

1858 scCAT-seq：single-cell identification and quantification of mRNA isoforms by cost-effective short-read sequencing of cap and tail

hu, y.; zhong, j.; xiao, y.; xing, z.; Sheu, K. M.; fan, s.; an, q.; qiu, y.; zheng, y.; liu, x.; Fan, G.; Liu, Y.

10.1101/2019.12.11.873505 — genomics — Posted on 2019-12-12

1859 Reduced transfer coefficient of carbon monoxide in pulmonary arterial hypertension implicates rare protein-truncating variants in KDR

10.1101/2019.12.11.871210 — genetics — Posted on 2019-12-12

1860 Population structure and clonal prevalence of scleractinian corals (Montipora capitata and Porites compressa) in Kaneohe Bay, Oahu

Locatelli, N. S.; Drew, J.

10.1101/2019.12.11.860585 — ecology — Posted on 2019-12-12

1861 The importance of Indigenous Peoples lands for the conservation of terrestrial vertebrates

O'Bryan, C. J.; Garnett, S. T.; Fa, J. E.; Leiper, I.; Rehbein, J.; Fernandez-Llamazares, A.; Jonas, H. D.; Brondizio, E.; Burgess, N.; Robinson, C.; Zander, K.; Venter, O.; Watson, J. E.

10.1101/2019.12.11.873695 — ecology — Posted on 2019-12-12

1862 Preference and familiarity mediate spatial responses of a large herbivore to experimental manipulation of resource availability

Ranc, N.; Moorcroft, P. R.; Hansen, K. W.; Ossi, F.; Sforna, T.; Brugnoli, A.; Ferraro, E.; Cagnacci, F.

10.1101/757757 — ecology — Posted on 2019-12-12

1863 Mechano-responsiveness of fibrillar adhesions on stiffness-gradient gels

Barber-Perez, N.; Georgiadou, M.; Guzman, C.; Isomursu, A.; Hamidi, H.; Ivaska, J.

10.1101/775809 — cell biology — Posted on 2019-12-12

1864 Flapping at Resonance: Measuring the Frequency Response of the Hymonptera Thorax

Jankauski, M.

10.1101/2019.12.11.873562 — bioengineering — Posted on 2019-12-12

1865 Examining the relationships between phenotypic plasticity and local environments with genomic structural equation models

Campbell, M. T.; Yu, H.; Momen, M.; Morota, G.

10.1101/2019.12.11.873257 — genomics — Posted on 2019-12-12

1866 The genetic basis of sex determination in grapevines (Vitis spp.)

Massonnet, M.; Cochetel, N.; Minio, A.; Muyle, A.; Lin, J.; Garcia, J. F.; Vondras, A. M.; Zhou, Y.; Delledonne, M.; Riaz, S.; Gaut, B. S.; Cantu, D.

10.1101/2019.12.11.861377 — evolutionary biology — Posted on 2019-12-12

1867 In Vitro Platform Establishes Antigen-Specific CD8+ T Cell Cytotoxicity to Encapsulated Cells via Indirect Antigen Recognition

Li, Y.; Frei, A. W.; Yang, E.; Labrada-Miravet, I.; Sun, C.; Rong, Y.; Samojlik, M. M.; Bayer, A. L.; Stabler, C. L.

10.1101/2019.12.11.872978 — bioengineering — Posted on 2019-12-12

1868 Track-Control, an automatic video-based real-time closed-loop behavioral control toolbox

Zhang, G.-W.; Shen, L.; Li, Z.; Tao, H. W.; Zhang, L. I.

10.1101/2019.12.11.873372 — animal behavior and cognition — Posted on 2019-12-12

1869 A Registration and Deep Learning Approach to Automated Landmark Detection for Geometric Morphometrics

Devine, J.; Aponte, J. D.; Katz, D. C.; Liu, W.; Lo Vercio, L. D.; Forkert, N. D.; Percival, C. J.; Hallgrimsson, B.

10.1101/2019.12.11.873182 — evolutionary biology — Posted on 2019-12-12

1870 Predicting Geographic Location From Genetic Variation with Deep Neural Networks

Battey, C. J.; Ralph, P. L.; Kern, A. D.

10.1101/2019.12.11.872051 — genetics — Posted on 2019-12-12

1871 Calibrating seed-based alignment heuristics with Sesame

Filion, G. J.; Cortini, R.; Zorita, E. V.

10.1101/619155 — bioinformatics — Posted on 2019-12-12

1872 Evidence for dual targeting of Arabidopsis plastidial glucose-6-phosphate transporter GPT1 to peroxisomes via the ER

Baune, M.-C.; Lansing, H.; Fischer, K.; Meyer, T.; Charton, L.; Linka, N.; von Schaewen, A.

10.1101/2019.12.11.873000 — plant biology — Posted on 2019-12-12

1873 A receptor-like kinase mediated phosphorylation of Gα protein affects signaling during nodulation

Roy Choudhury, S.; Pandey, S.

10.1101/2019.12.11.873190 — plant biology — Posted on 2019-12-12

1874 Larval thermal characteristics of multiple ixodid ticks underlie their range dynamics

Fieler, A.; Rosendale, A.; Farrow, D.; Dunlevy, M.; Davies, B.; Oyen, K.; Benoit, J.

10.1101/2019.12.11.873042 — physiology — Posted on 2019-12-12

1875 The effect of left frontal resection on hand selection: a lesion-tractography study

Howells, H.; Puglisi, G.; Leonetti, A.; Vigano, L.; Fornia, L.; Simone, L.; Forkel, S.; Rossi, M.; Riva, M.; Cerri, G.; Bello, L.

10.1101/2019.12.11.872754 — neuroscience — Posted on 2019-12-12

1876 Localization of the signal of dystonia-associated protein torsinA near the Golgi apparatus in cultured central neurons

Iwabuchi, S.; Kawano, H.; Harata, N. C.

10.1101/2019.12.11.872804 — neuroscience — Posted on 2019-12-12

1877 Sensorimotor neuronal learning requires cortical topography

Abbasi, A.; Estebanez, L.; Goueytes, D.; Lassagne, H.; Shulz, D. E.; Ego-Stengel, V.

10.1101/2019.12.12.873794 — neuroscience — Posted on 2019-12-12

1878 Situating the Left-Lateralized Language Network in the Broader Organization of Multiple Specialized Large-Scale Distributed Networks

Braga, R. M.; DiNicola, L. M.; Buckner, R. L.

10.1101/2019.12.11.873174 — neuroscience — Posted on 2019-12-12

1879 Analysis of brain atrophy and local gene expression implicates astrocytes in Frontotemporal dementia

Altmann, A.; Cash, D. M.; Bocchetta, M.; Heller, C.; Reynolds, R. H.; Moore, K.; Convery, R. S.; Thomas, D.; van Swieten, J. C.; Moreno, F.; Sanchez-Valle, R.; Borroni, B.; Laforce, R.; Masellis, M.; Tartaglia, C.; Graff, C.; Galimberti, D.; Rowe, J.; Finger, E.; Synofzik, M.; Vandenberghe, R.; de Mendonca, A.; Tagliavini, F.; Santana, I.; Ducharme, S.; Butler, C.; Gerhard, A.; Levin, J.; Danek, A.; Frisoni, G.; Ghidoni, R.; Sorbi, S.; Otto, M.; Ryten, M.; Rohrer, J. D.; Genetic FTD Initiative, GENFI,

10.1101/2019.12.11.872143 — neuroscience — Posted on 2019-12-12

1880 Sensitivity to grayscale textures is adapted to natural scene statistics

Tesileanu, T.; Conte, M. M.; Briguglio, J. J.; Hermundstad, A. M.; Victor, J. D.; Balasubramanian, V.

10.1101/2019.12.11.872994 — neuroscience — Posted on 2019-12-12

1881 Microglia Clear Neuron-released α-Synuclein via Selective Autophagy and Prevent Neurodegeneration

Choi, I.; Zhang, Y.; Seegobin, S. P.; Pruvost, M.; Wang, Q.; Purtell, K.; Zhang, B.; Yue, Z.

10.1101/2019.12.11.872812 — neuroscience — Posted on 2019-12-12

1882 ParB spreading on DNA requires cytidine triphosphate in vitro

Jalal, A. S. B.; Tran, N. T.; Le, T. B. K.

10.1101/2019.12.11.865972 — microbiology — Posted on 2019-12-12

1883 Electron transfer complexes in the gut dictate high abundance circulating metabolites

Liu, Y.; Van Treuren, W.; Hou, B.-H.; Higginbottom, S. K.; Sonnenburg, J. L.; Dodd, D.

10.1101/2019.12.11.873224 — microbiology — Posted on 2019-12-12

1884 Early life glucocorticoid exposure modulates immune function in zebrafish (Danio rerio) larvae

van den Bos, R.; Cromwijk, S.; Tschigg, K.; Althuizen, J.; Zethof, J.; Whelan, R.; Flik, G.; Schaaf, M.

10.1101/2019.12.11.872903 — immunology — Posted on 2019-12-12

1885 Chromosome-scale genome assembly provides insights into rye biology, evolution, and agronomic potential

Rabanus-Wallace, M. T.; Hackauf, B.; Mascher, M.; Lux, T.; Wicker, T.; Gundlach, H.; Baez, M.; Houben, A.; Mayer, K. F. X.; Guo, L.; Poland, J.; Pozniak, C. J.; Walkowiak, S.; Melonek, J.; Praz, C.; Schreiber, M.; Budak, H.; Heuberger, M.; Steuernagel, B.; Wulff, B.; Boerner, A.; Byrns, B.; Cizkova, J.; Fowler, D. B.; Fritz, A.; Himmelbach, A.; Kaithakottil, G.; Keilwagen, J.; Keller, B.; Konkin, D.; Larsen, J.; Myskow, B.; Padmarasu, S.; Rawat, N.; Sesiz, U.; Sezgi, B.; Sharpe, A.; Simkova, H.; Small, I.; Swarbreck, D.; Toegelova, H.; Tsvetkova, N.; Voylokov, A. V.; Vrana, J.; Bauer, E.; Boli

10.1101/2019.12.11.869693 — genomics — Posted on 2019-12-12

1886 The Human Accelerated Region HACNS1 modifies developmental gene expression in humanized mice

Dutrow, E. V.; Emera, D.; Yim, K.; Uebbing, S.; Kocher, A. A.; Krenzer, M.; Nottoli, T.; Burkhardt, D. B.; Krishnaswamy, S.; Louvi, A.; Noonan, J. P.

10.1101/2019.12.11.873075 — genetics — Posted on 2019-12-12

1887 Kin selection, not indirect reciprocity, explains helping those who help others in image scoring

Roberts, G.

10.1101/2019.12.11.872937 — evolutionary biology — Posted on 2019-12-12

1888 Combining genotype, phenotype, and environmental data to delineate site-adjusted provenance strategies for ecological restoration

Carvalho, C. d. S.; Forester, B. R.; Mitre, S. K.; Alves, R.; Imperatriz-Fonseca, V. L.; Ramos, S. J.; Resende-Moreira, L. C.; Siqueira, J. O.; Trevelin, L. C.; Caldeira, C. F.; Gastauer, M.; Jaffe, R.

10.1101/2019.12.11.872747 — ecology — Posted on 2019-12-12

1889 Quantitative method for estimating stain density in electron microscopy of conventionally prepared biological specimens

Fera, A.; He, Q.; Zhang, G.; Leapman, R. D.

10.1101/2019.12.11.873323 — biophysics — Posted on 2019-12-12

1890 Biofilm and Cell Adhesion Strength on Dental Implant Surfaces via the Laser Spallation Technique

Boyd, J. D.; Miller, C. S.; Grady, M. E.

10.1101/2019.12.11.873240 — bioengineering — Posted on 2019-12-12

1891 Honest signalling of trustworthiness

Roberts, G.

10.1101/2019.12.11.873208 — animal behavior and cognition — Posted on 2019-12-12

1892 Single cell atlas of domestic pig brain illuminates the conservation and divergence of cell types at spatial and species levels

Chen, D.; Zhu, J.; Zhong, J.; Chen, F.; Lin, X.; Dai, J.; Chen, Y.; Wang, S.; Ding, X.; Wang, H.; Qiu, J.; Wang, F.; Wu, W.; Liu, P.; Tang, G.; Qiu, X.; Ruan, Y.; Li, J.; Zhu, S.; Xu, X.; Li, F.; Liu, Z.; Cao, G.

10.1101/2019.12.11.872721 — bioinformatics — Posted on 2019-12-12

1893 Targeting the Long Non-Coding RNA LINC00599-205 splicing by novel candidate drug ABX464 to produce anti-inflammatory MicroRNA miR-124

Manchon, L.; Vautrin, A.; Garcel, A.; Campos, N.; Tazi, J.

10.1101/2019.12.11.871335 — immunology — Posted on 2019-12-12

1894 The lipid transfer function of RDGB at ER-PM contact sites is regulated by multiple interdomain interactions.

Basak, B.; Krishnan, H.; Raghu, P.

10.1101/2019.12.12.873810 — cell biology — Posted on 2019-12-12

1895 Combined salinity and acidity stressors alter Daphnia magna population growth and structure under prolonged absence of photoperiod

Khudr, M. S.; Purkiss, S. A.; Hager, R.

10.1101/2019.12.11.872630 — zoology — Posted on 2019-12-12

1896 A modular RNA interference system for gene regulation and robust dynamic feedback control

Dwijayanti, A.; Storch, M.; Stan, G.-B. V.; Baldwin, G.

10.1101/2019.12.12.873844 — synthetic biology — Posted on 2019-12-12

1897 Carbon Nanocarriers Deliver siRNA to Intact Plant Cells for Efficient Gene Knockdown

Demirer, G. S.; Zhang, H.; Goh, N. S.; Pinals, R. L.; Chang, R.; Landry, M. P.

10.1101/564427 — plant biology — Posted on 2019-12-12

1898 Element content and distribution has limited, tolerance metric dependent, impact on salinity tolerance in cultivated sunflower (Helianthus annuus)

Temme, A. A.; Burns, V. A.; Donovan, L. A.

10.1101/2019.12.11.872929 — plant biology — Posted on 2019-12-12

1899 Chr21 protein-protein interactions: enrichment in products involved in intellectual disabilities, autism and Late Onset Alzheimer Disease

Viard, J.; Loe-Mie, Y.; Khelfaoui, M.; Daudin, R.; Plancon, C.; Boland, A.; Tejedor, F.; Huganir, R.; Kim, E.; Kinoshita, M.; Liu, G.; Haucke, V.; Moncion, T.; Yu, E.; Hindie, V.; Blehaut, H.; Mircher, C.; Herault, Y.; Deleuze, J.-F.; Rain, J.-C.; Simonneau, M.; Lepagnol-Bestel, A.-M.

10.1101/2019.12.11.872606 — neuroscience — Posted on 2019-12-12

1900 Tracking attention in a visual active paradigm for the diagnosis of disorders of consciousness

Lesenfants, D.; Chatelle, C.; Noirhomme, Q.; Laureys, S.

10.1101/2019.12.11.872515 — neuroscience — Posted on 2019-12-12

1901 Differential contributions of left-hemispheric language regions to basic semantic composition

Graessner, A.; Zaccarella, E.; Hartwigsen, G.

10.1101/2019.12.11.872457 — neuroscience — Posted on 2019-12-12

1902 The DNA end-binding protein Ku associates with human telomeres primarily via protein-protein interactions

Sukumar, A.; Williams, C. L.; Jones, C. Y.; Asik, E.; Morris, D. K.; Baldan, A.; Indiviglio, S. M.; Chiodi, I.; Mondello, C.; Bertuch, A. A.

10.1101/2019.12.11.873422 — molecular biology — Posted on 2019-12-12

1903 Cell-Specific Regulation of Intestinal Immunity.

Shin, M.; Willms, R. J.; Jones, L. O.; Panteluk, A.; Foley, E.

10.1101/721662 — immunology — Posted on 2019-12-12

1904 Methods detecting rhythmic gene expression are only biologically relevant for strong signal.

Laloum, D.; Robinson-Rechavi, M.

10.1101/730937 — bioinformatics — Posted on 2019-12-12

1905 Lactobacillus reuteri: direct passage from ingested yogurts to urine microbiota

Lagier, J. C.; Mekhalif, F.; Merhej, V.; Chaudet, H.; Delerce, J.; Levasseur, A.; Raoult, D.

10.1101/2019.12.11.872788 — microbiology — Posted on 2019-12-12

1906 Physiological and genomic analysis of Candidatus Nitrosocosmicus agrestis, an ammonia tolerant ammonia-oxidizing archaeon from vegetable soil

Liu, L.; Liu, M.; Jiang, Y.; Lin, W.; Luo, J.

10.1101/2019.12.11.872556 — microbiology — Posted on 2019-12-12

1907 Unveiling two new trichome-specific promoters of Nicotiana tabacum

Pottier, M.; Laterre, R.; Van Wessem, A.; M. Ramirez, A.; Herman, X.; Boutry, M.; Hachez, C.

10.1101/620021 — plant biology — Posted on 2019-12-12

1908 Gut microbiome signatures of risk and prodromal markers of Parkinson's disease

Heinzel, S.; Aho, V. T. E.; Suenkel, U.; von Thaler, A.-K.; Schulte, C.; Deuschle, C.; Hantunen, S.; Brockmann, K.; Eschweiler, G. W.; Maetzler, W.; Berg, D.; Auvinen, P.; Scheperjans, F.

10.1101/2019.12.11.872481 — neuroscience — Posted on 2019-12-12

1909 Robust representation of natural images by sparse and variable population of active neurons in visual cortex

Yoshida, T.; Ohki, K.

10.1101/300863 — neuroscience — Posted on 2019-12-12

1910 Systems genetics analysis identify calcium signalling defects as novel cause of congenital heart disease

Izarzugaza, J. M. G.; Ellesoe, S. G.; Doganli, C.; Ehlers, N. S.; Dalgaard, M. D.; Audain, E.; Dombrowsky, G.; Sifrim, A.; Wilsdon, A.; Thienpont, B.; Breckpot, J.; Gewillig, M.; Competence Network for Congenital Heart Defects, Germany, ; Brook, J. D.; Hitz, M.-P.; Larsen, L. A.; Brunak, S.

10.1101/2019.12.11.872424 — genetics — Posted on 2019-12-12

1911 RamaNet: Computational De Novo Helical Protein Backbone Design using a Long Short-Term Memory Generative Adversarial Neural Network

Sabban, S.; Markovsky, M.

10.1101/671552 — bioinformatics — Posted on 2019-12-12

1912 The TFIIH subunits p44/p62 act as a damage sensor during nucleotide excision repair

Barnett, J. T.; Kuper, J.; Koelmel, W.; Kisker, C.; Kad, N. M.

10.1101/643874 — biochemistry — Posted on 2019-12-12

1913 Let a monkey do your bidding: Reward valuation in an auction-like mechanism

Al Mohammad, A.; Schultz, W.

10.1101/2019.12.11.872564 — animal behavior and cognition — Posted on 2019-12-12

1914 Multi-photon attenuation-compensated light-sheet fluorescence microscopy

Veettikazhy, M.; Nylk, J.; Gasparoli, F.; Escobet-Montalban, A.; Hansen, A. K.; Marti, D.; Andersen, P. E.; Dholakia, K.

10.1101/2019.12.12.873877 — cell biology — Posted on 2019-12-12

1915 Robust nucleation control via crisscross polymerization of DNA slats

Minev, D.; Wintersinger, C.; Ershova, A.; Shih, W.

10.1101/2019.12.11.873349 — synthetic biology — Posted on 2019-12-12

1916 Microglia dysfunction caused by the loss of Rhoa disrupts neuronal physiology and leads to neurodegeneration

Socodato, R.; Portugal, C. C.; Canedo, T.; Rodrigues, A.; Henriques, J.; Vaz, S. H.; Magalhaes, J. D.; Silva, C. M.; Baptista, F. I.; Alves, R. L.; Nogueira, J.; Coelho-Santos, V.; Silva, A. P.; Paes-de-Carvalho, R.; Magalhaes, A.; Summavielle, T.; Brakebusch, C.; Sebastiao, A. M.; Ambrosio, A. F.; Relvas, J. B.

10.1101/218107 — neuroscience — Posted on 2019-12-12

1917 Peax: Interactive Visual Pattern Search in Sequential Data Using Unsupervised Deep Representation Learning

Lekschas, F.; Peterson, B.; Haehn, D.; Ma, E.; Gehlenborg, N.; Pfister, H.

10.1101/597518 — genomics — Posted on 2019-12-12

1918 SingleCellSignalR: Inference of intercellular networks from single-cell transcriptomics

Cabello-Aguilar, S.; Kon Sun Tack, F.; Alame, M.; Fau, C.; Lacroix, M.; Colinge, J.

10.1101/2019.12.11.872895 — bioinformatics — Posted on 2019-12-12

1919 REPIC: A database for exploring N6-methyladenosine methylome

Liu, S.; He, C.; Chen, M.

10.1101/2019.12.11.873299 — bioinformatics — Posted on 2019-12-12

1920 Selection for rapid uptake of scarce or fluctuating resource explains vulnerability of glycolysis to imbalance

Janulevicius, A.; van Doorn, G. S.

10.1101/2019.12.12.873315 — systems biology — Posted on 2019-12-12

1921 A high-throughput screen for transcription activation domains reveals their sequence characteristics and permits reliable prediction by deep learning

Erijman, A.; Kozlowski, L.; Sohrabi-Jahromi, S.; Fishburn, J.; Warfield, L.; Schreiber, J.; Noble, W. S.; Soeding, J.; Hahn, S.

10.1101/2019.12.11.872986 — molecular biology — Posted on 2019-12-12

1922 Wwc2 is a novel mitotic/meiotic cell-cycle regulator and cell fate related gene, during preimplantation mouse embryo development and oogenesis

Virnicchi, G.; Bora, P.; Gahurova, L.; Susor, A.; Bruce, A. W.

10.1101/2019.12.12.872366 — developmental biology — Posted on 2019-12-12

1923 Geldanamycin inhibits Jumonji histone lysine demethylase KDM4 and targets chimeric transcription factor PAX3-FOXO1

Abu-Zaid, A.; Singh, S.; LIN, W.; Low, J.; Abdolvahabi, A.; Bailey Cooke, B.; Bowling, J.; Vaithiyalingam, S.; Fang, J.; Currier, D.; Yun, M.-K.; AlTahan, A.; Fernando, D.; Maier, J.; Tillman, H.; Bulsara, P.; Lu, Z.; Li, Z. L.; Young, B.; Lee, R.; Rankovic, Z.; White, S.; Davidoff, A.; Chen, T.; YANG, J.

10.1101/2019.12.11.872838 — cancer biology — Posted on 2019-12-12

1924 Early sexual dimorphism in the developing gut microbiome of northern elephant seals

Stoffel, M. A.; Acevedo-Whitehouse, K.; Morales-Duran, N.; Grosser, S.; Chakarov, N.; Krüger, O.; Nichols, H. J.; Elorriaga-Verplancken, F. R.; Hoffman, J. I.

10.1101/2019.12.11.871855 — molecular biology — Posted on 2019-12-12

1925 Molecular Investigations into the Unfoldase Action of Severing Enzymes on Microtubules

Varikoti, R. A.; Macke, A.; Speck, V.; Ross, J. L.; Dima, R. I.

10.1101/2019.12.11.873273 — biophysics — Posted on 2019-12-12

1926 An allosteric switch regulates Mycobacterium tuberculosis ClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR

Vahidi, S.; Ripstein, Z. A.; Juravsky, J. B.; Rennella, E.; Goldberg, A. L.; Mittermaier, A. K.; Rubinstein, J. L.; Kay, L. E.

10.1101/2019.12.11.873281 — biophysics — Posted on 2019-12-12

1927 Expansion and re-classification of the extracytoplasmic function (ECF) σ factor family

Casas Pastor, D.; Müller, R. R.; Becker, A.; Buttner, M.; Gross, C.; Mascher, T.; Goesmann, A.; Fritz, G.

10.1101/2019.12.11.873521 — bioinformatics — Posted on 2019-12-12

1928 Bromodomain inhibition reveals FGF15/19 as a target of epigenetic regulation and metabolic control

Kozuka, C.; Sales, V.; Osataphan, S.; Yuchi, Y.; Chimene-Weiss, J.; Mulla, C.; Isganaitis, E.; Desmond, J.; Sanechika, S.; Kusuyama, J.; Goodyear, L.; Shi, X.; Gerszten, R. E.; Wu, L.; Qi, J.; Patti, M. E.

10.1101/2019.12.11.872887 — systems biology — Posted on 2019-12-12

1929 Human NMD ensues independently of stable ribosome stalling

Karousis, E. D.; Gurzeler, L.-A.; Annibaldis, G.; Dreos, R.; Muhlemann, O.

10.1101/2019.12.11.872861 — molecular biology — Posted on 2019-12-12

1930 Islet architecture controls synchronous β cell response to glucose in the intact mouse pancreas in vivo

Adams, M. T.; Reissaus, C. A.; Szulczewski, J. M.; Dwulet, J. M.; Lyman, M. R.; Sdao, S. M.; Nimkulrat, S. D.; Ponik, S. M.; Merrins, M. J.; Benninger, R. K. P.; Mirmira, R. G.; Linnemann, A. K.; Blum, B.

10.1101/2019.12.11.873471 — developmental biology — Posted on 2019-12-12

1931 The proline synthesis enzyme P5CS forms cytoophidia in Drosophila

Zhang, B.; Tastan, O. Y.; Zhou, X.; Guo, C.-J.; Liu, X.; Thind, A.; Hu, H.-H.; Zhao, S.; Liu, J.-L.

10.1101/2019.12.11.872267 — cell biology — Posted on 2019-12-12

1932 Structure of Biomolecular Condensates from Dissipative Particle Dynamics Simulations

Shillcock, J. C.; Brochut, M.; Chenais, E.; Ipsen, J. H.

10.1101/2019.12.11.873133 — biophysics — Posted on 2019-12-12

1933 Measurements of 3-D morphology of individual red blood cells upon localized photothermal effects using gold nanorods

Song, C.; Lee, G.-H.; Oh, J.; Lee, M.; Shin, S.; Lee, S.; Nam, Y.; Park, Y.

10.1101/2019.12.11.872218 — biophysics — Posted on 2019-12-12

1934 Modeling subcortical white matter stimulation

Dali, M.; Goldman, J. S.; Pantz, O.; Destexhe, A.; Mandonnet, E.

10.1101/2019.12.12.872390 — biophysics — Posted on 2019-12-12

1935 Rapid assessment of phytoplankton assemblages using Next Generation Sequencing - Barcode of Life database: a widely applicable toolkit to monitor biodiversity and harmful algal blooms (HABs)

Ivanova, N. V.; Watson, L. C.; Comte, J.; Bessonov, K.; Abrahamyan, A.; Davis, T. W.; Bullerjahn, G. S.; Watson, S. B.

10.1101/2019.12.11.873034 — molecular biology — Posted on 2019-12-12

1936 Participation of the rostral anterior cingulate cortex in defensive behavior induced by electrical stimulation of the dorsal periaqueductal gray and contextual fear conditioning

Galvao, B. o.; Filgueiras, A.; Maisonnette, S.; Krahe, T. E.; Landeira-Fernandez, J.

10.1101/872648 — neuroscience — Posted on 2019-12-11

1937 Interspecific hierarchies from aggressiveness and body size among the invasive alien hornet, Vespa velutina nigrithorax, and five native hornets in South Korea

Choi, M. B.; Kwon, O.

10.1101/872655 — animal behavior and cognition — Posted on 2019-12-11

1938 Assessment of Water Stress Tolerance in Mungbean Induced by Polyethyline Glycol

elsabagh, a.; Islam, M. R.; Islam, M. S.; Sarker, B. C.; Alam, M. A.; Akhter, M. M.; Alam, M. J.; Saneoka, H.; Erman, M.

10.1101/872663 — plant biology — Posted on 2019-12-11

1939 M-current downregulation leads to stellate ganglia sympathetic hyperactivity associated with hypertension

Davis, H.; Herring, N.; Paterson, D. J.

10.1101/2019.12.11.872580 — neuroscience — Posted on 2019-12-11

1940 Comparative Genomics of Six Juglans Species Reveals Patterns of Disease-associated Gene Family Contractions.

Trouern-Trend, A. J.; Falk, T. A.; Zaman, S.; Caballero, M.; Neale, D. B.; Langley, C. H.; Dandekar, A.; Stevens, K.; Wegrzyn, J.

10.1101/561738 — genomics — Posted on 2019-12-11

1941 Computer aided interactive gene network simulations including stochastic molecular kinetics and noise

Hettich, J.; Gebhardt, J. C. M.

10.1101/872374 — systems biology — Posted on 2019-12-11

1942 Viola unica (Violaceae L.), a very rare, high elevation, single site new species endemic to the northern semi-desert Altiplano of Chile

Flores, A. R.; Watson, J. M.

10.1101/787564 — plant biology — Posted on 2019-12-11

1943 The neural representation of emotion is high-dimensional, categorical, and distributed across transmodal brain regions

Horikawa, T.; Cowen, A. S.; Keltner, D.; Kamitani, Y.

10.1101/872192 — neuroscience — Posted on 2019-12-11

1944 Complex deletion and proximal reinsertion of a 150bp regulatory sequence in the mouse Csf1r promoter mediated by CRISPR-Cas9.

Summers, K.; Pridans, C.; Wollscheid-Lengeling, E.; Grabert, k.; Adamson, A.; Humphreys, N. E.; Irvine, K. M.; Hume, D. A.

10.1101/872200 — molecular biology — Posted on 2019-12-11

1945 A conserved translation factor is required for optimal synthesis of a membrane protein family in mycobacteria

Fishbein, S.; Wolf, I. D.; Dulberger, C. L.; Wang, A.; Keshishian, H.; Wallace, L.; Carr, S. A.; Ioerger, T. R.; Rubin, E. J.; Rego, E. H.

10.1101/872341 — microbiology — Posted on 2019-12-11

1946 Multiple requirements for Rab GTPases in the development of Drosophila tracheal dorsal branches and terminal cells

Best, B. T.; Leptin, M.

10.1101/873232 — developmental biology — Posted on 2019-12-11

1947 FGF9 and FGF10 use distinct signaling pathways to direct lung epithelial specification and branching

Yin, Y.; Ornitz, D. M.

10.1101/873109 — developmental biology — Posted on 2019-12-11

1948 A key regulatory protein for flagellum length control in stable flagella

Atkins, M.; Tyc, J.; Shafiq, S.; Ahmed, M.; Bertiaux, E.; De castro neto, A. L.; Sunter, J.; Bastin, P.; Dean, S.; Vaughan, S.

10.1101/872952 — cell biology — Posted on 2019-12-11

1949 Mesoscale Dynamics of Spectrin and Acto-Myosin shape Membrane Territories during Mechanoresponse

Ghisleni, A.; Galli, C.; Monzo, P.; Ascione, F.; Fardin, M. A.; Scita, G.; Li, Q.; Maiuri, P.; Gauthier, N.

10.1101/872465 — cell biology — Posted on 2019-12-11

1950 Variation in repeat copy number of epithelial adhesin 1 tandem repeat region leads to variable protein display through multiple mechanisms

Raposo, C. J.; McElroy, K. A.; Fuchs, S. M.

10.1101/872853 — cell biology — Posted on 2019-12-11

1951 Cholangiocarcinoma presents a distinct myeloid-derived suppressor cell signature compared to other hepatobiliary cancers

Bayik, D.; Lauko, A.; Roversi, G. A.; Serbinowski, E.; Acevedo-Moreno, L.-A.; Lanigan, C.; Orujov, M.; Lo, A.; Alban, T.; Silver, D. J.; Brown, J. M.; Allende, D. S.; Aucejo, F. N.; Lathia, J. D.

10.1101/554600 — pathology — Posted on 2019-12-11

1952 Studies of NH4+ and NO3- uptake ability of subalpine plants and resource-use strategy identified by their functional traits.

Legay, N.; Grassein, F.; Arnoldi, C.; Raphael, S.; Philippe, L.; Lavorel, S.; Clement, J.-C.

10.1101/372235 — ecology — Posted on 2019-12-11

1953 Learning Complex Representations from Spatial Phase Statistics of Natural Scenes

MaBouDi, H.; Subramani, K.; Soltanian-Zadeh, H.; Amari, S.-i.; Shimazaki, H.

10.1101/112813 — neuroscience — Posted on 2019-12-11

1954 Aurora B and C kinases regulate prophase exit and chromosome segregation during spermatogenesis

Wellard, S. R.; Schindler, K.; Jordan, P.

10.1101/868836 — cell biology — Posted on 2019-12-11

1955 Syntrophy via interspecies H2 transfer between Christensenella and Methanobrevibacter underlies their global co-occurrence in the human gut

Ruaud, A.; Esquivel-Elizondo, S.; de la Cuesta-Zuluaga, J.; Waters, J. L.; Angenent, L. T.; Youngblut, N. D.; Ley, R. E.

10.1101/872333 — microbiology — Posted on 2019-12-11

1956 Human intestinal tissue-resident memory CD8+ T cells comprise transcriptionally and functionally distinct subsets

FitzPatrick, M. E. B.; Provine, N. M.; Garner, L. C.; Powell, K.; Amini, A.; Irwin, S.; Ferry, H.; Ambrose, T.; Friend, P.; Vrakas, G.; Reddy, S.; Soilleux, E. J.; Klenerman, P.; Allan, P. J.

10.1101/869917 — immunology — Posted on 2019-12-11

1957 Role of SHIP2 in cell repulsion regulated by Eph receptor and ephrin signaling

Ashlin, T. G.; Wu, Z.; Xu, Q.; Wilkinson, D.

10.1101/872846 — cell biology — Posted on 2019-12-11

1958 Dissecting intratumor heterogeneity of nodal B cell lymphomas on the transcriptional, genetic, and drug response level

Roider, T.; Seufert, J.; Uvarovskii, A.; Frauhammer, F.; Bordas, M.; Abedpour, N.; Stolarczyk, M.; Mallm, J.-P.; Rabe, S.; Bruch, P.-M.; Balke-Want, H.; Hundemer, M.; Rippe, K.; Goeppert, B.; Seiffert, M.; Brors, B.; Mechtersheimer, G.; Chapuy, B.; Schlesner, M.; Zenz, T.; Pfeifer, M.; Fröhling, S.; Müller-Tidow, C.; Huber, W.; Anders, S.; Dietrich, S.

10.1101/850438 — cancer biology — Posted on 2019-12-11

1959 Linker histone variant H1t is closely associated with repressed repeat-element chromatin domains in pachytene spermatocytes

Iyer, A. M.; Kumar, S.; Rao, S. M. R.

10.1101/872408 — cell biology — Posted on 2019-12-11

1960 The "adductome": a limited repertoire of adducted proteins in human cells

Kiianitsa, K.; Maizels, N.

10.1101/872176 — biochemistry — Posted on 2019-12-11

1961 The Vitamin D Receptor (VDR) Regulates Mitochondrial Function in C2C12 Myoblasts

Ashcroft, S.; Bass, J. J.; Kazi, A.; Atherton, P. J.; Philp, A.

10.1101/872127 — physiology — Posted on 2019-12-11

1962 Recombinant HcGAPDH Protein Expressed on Probiotic Bacillus subtilis Spores Protects Sheep from Haemonchus contortus Infection by Inducing both Humoral and Cell-mediated Responses

Yang, Y.; Zhang, G.; Wu, J.; Chen, X.; Tong, D.; Yang, Y.; Shi, H.; Yao, C.; Zhuang, L.; Wang, J.; Du, A.

10.1101/872291 — microbiology — Posted on 2019-12-11

1963 Nearly unbiased estimator of Ne/N based on kinship relationships

Akita, T.

10.1101/872168 — ecology — Posted on 2019-12-11

1964 Leaf chemical defences and insect herbivory in oak: accounting for canopy position unravels marked genetic relatedness effects

Valdes-Correcher, E.; Bourdin, A.; Gonzalez-Martinez, S. C.; Moreira, X.; Galman, A.; Castagneyrol, B.; Hampe, A.

10.1101/872549 — ecology — Posted on 2019-12-11

1965 Negros Bleeding-heart Gallicolumba keayi prefers dense understorey vegetation and dense canopy cover, and species distribution modelling shows little remaining suitable habitat

Mynott, H. I.; Kerhoas, M. I.; Kerhoas, D.

10.1101/872044 — zoology — Posted on 2019-12-11

1966 DeepInsight: A general framework for interpreting wide-band neural activity

Frey, M.; Tanni, S.; Perrodin, C.; O'Leary, A.; Nau, M.; Kelly, J.; Banino, A.; Doeller, C. F.; Barry, C.

10.1101/871848 — neuroscience — Posted on 2019-12-11

1967 Dimensions of anxiety and depression and neurophysiological indicators of error-monitoring: Relationship with delta and theta oscillatory power and error-related negativity amplitude

Muir, A. M.; Hedges-Muncy, A.; Clawson, A.; Carbine, K. A.; Larson, M. J.

10.1101/872119 — neuroscience — Posted on 2019-12-11

1968 ScmR, a global regulator of gene expression, quorum sensing, pH homeostasis, and virulence in Burkholderia thailandensis

Le Guillouzer, S.; Groleau, M.-C.; Mauffrey, F.; Deziel, E.

10.1101/871871 — microbiology — Posted on 2019-12-11

1969 T-cell immunoglobulin and mucin (TIM) contributes to Hantaan virus entry into human airway epithelial cells

Mayor, J.; Torriani, G.; Zimmer, G.; Rothenberger, S.; Engler, O.

10.1101/872317 — microbiology — Posted on 2019-12-11

1970 Local adaptation fuels cryptic speciation in terrestrial annelids

Marchan, D. F.; Novo, M.; Sanchez, N.; Dominguez, J.; Diaz Cosin, D. J.; Fernandez, R.

10.1101/872309 — evolutionary biology — Posted on 2019-12-11

1971 Geometric regulation of histone state directs melanoma reprogramming

Lee, J.; Molley, T. G.; Seward, C. H.; Abdeen, A. A.; Zhang, H.; Wang, X.; Gandhi, H.; Yang, J.-L.; Gaus, K.; Kilian, K. A.

10.1101/872226 — cancer biology — Posted on 2019-12-11

1972 Geochemical influences on nonenzymatic oligomerization of prebiotically relevant cyclic nucleotides

Dagar, S.; Sarkar, S.; Rajamani, S.

10.1101/872234 — biochemistry — Posted on 2019-12-11

1973 Latent space visualization, characterization, and generation of diverse vocal communication signals

Sainburg, T.; Thielk, M.; Gentner, T. Q.

10.1101/870311 — animal behavior and cognition — Posted on 2019-12-11

1974 A multi-dimensional, time-lapse, high content screening platform for the flatworm pathogen causing schistosomiasis

Chen, S.; Suzuki, B. M.; Dohrmann, J.; Singh, R.; Arkin, M. R.; Caffrey, C. R.

10.1101/872069 — microbiology — Posted on 2019-12-11

1975 Male accessory gland factors increased sex pheromone titres in the glands of Spodoptera litura female moths by inhibiting calling behavior

Xu, J.; Shi, M.-R.; Fu, D.-Y.; Yu, H.; Chen, P.

10.1101/872150 — zoology — Posted on 2019-12-11

1976 Effective buprenorphine use and tapering strategies: Endorsements and insights by people in recovery from opioid use disorder on a Reddit forum

Graves, R. L.; Sarker, A.; Al-Garadi, M. A.; Yang, Y.-c.; Love, J. S.; O'Connor, K.; Gonzalez-Hernandez, G.; Perrone, J.

10.1101/871608 — pharmacology and toxicology — Posted on 2019-12-11

1977 Fitness Functions Determine Optimal Parental Allocation: Redefining Trivers Willard Theory

Choi, J.; Roh, H.; Lee, S.-i.; Kwon, H.-D.; Kang, M.; Jablonski, P. G.

10.1101/870881 — evolutionary biology — Posted on 2019-12-11

1978 A molecular rack and pinion actuates a cell-surface adhesin and enables bacterial gliding motility

Shrivastava, A.; Berg, H. C.

10.1101/267583 — microbiology — Posted on 2019-12-11

1979 A Higher Proportion of Craniosynostosis Genes Are Cancer Driver Genes

Misra, S.; Shih, A.; Yan, X.-j.; Li, W.

10.1101/872093 — genetics — Posted on 2019-12-11

1980 Widespread interaction between ADAR1 and transcriptional byproducts

Wu, C. S.; Tang, S. J.; Tan, H. K.; Hung, L.-Y.; Teo, W. W.; Li, J.; An, O.; Tan, K. T.; Zhou, Q.; Chen, L.; Tenen, D. G.; Yang, H.

10.1101/870782 — genomics — Posted on 2019-12-11

1981 Genomic and transcriptomic evidence for descent from Plasmodium and loss of blood schizogony in Hepatocystis parasites from naturally infected red colobus monkeys

Aunin, E.; Boehme, U.; Sanderson, T.; Simons, N. D.; Goldberg, T. L.; Ting, N.; Chapman, C. A.; Newbold, C. I.; Berriman, M.; Reid, A. J.

10.1101/871327 — genomics — Posted on 2019-12-11

1982 A snapshot of progenitor-derivative speciation in action in Iberodes (Boraginaceae)

Otero, A.; Vargas, P.; Valcarcel, V.; Fernandez-Mazuecos, M.; Jimenez-Mejias, P.; Hipp, A. L.

10.1101/823641 — evolutionary biology — Posted on 2019-12-11

1983 Interdependent regulation of stereotyped and stochastic photoreceptor fates in the fly eye

Miller, A. C.; Urban, E.; Lyons, E. L.; Herman, T. G.; Johnston, R. J.

10.1101/865717 — developmental biology — Posted on 2019-12-11

1984 In silico stress fibre content affects peak strain in cytoplasm and nucleus but not in membrane for uniaxial substrate stretch

Abdalrahman, T.; Davies, N. H.; Franz, T.

10.1101/774976 — biophysics — Posted on 2019-12-11

1985 Crystal structure of the TbBILBO1 N-terminal domain reveals a ubiquitin fold with a long rigid loop for the binding of its partner

Dong, G.

10.1101/738153 — biochemistry — Posted on 2019-12-11

1986 How long do Red Queen dynamics survive under genetic drift? A comparative analysis of evolutionary and eco-evolutionary models

Schenk, H.; Schulenburg, H.; Traulsen, A.

10.1101/490201 — evolutionary biology — Posted on 2019-12-11

1987 The experimentally obtained functional impact assessments of GT>GC 5' splice site variants differ markedly from those predicted

Chen, J.-M.; Lin, J.-H.; Masson, E.; Liao, Z.; Ferec, C.; Cooper, D. N.; Hayden, M.

10.1101/864843 — genetics — Posted on 2019-12-11

1988 Structure of the processive human Pol δ holoenzyme

Lancey, C.; Tehseen, M.; Raducanu, V.-S.; Rashid, F.; Merino, N.; Ragan, T. J.; Savva, C.; Zaher, M. S.; Shirbini, A.; Blanco, F. J.; Hamdan, S. M.; De Biasio, A.

10.1101/872879 — biochemistry — Posted on 2019-12-11

1989 A Comparison of fMRI and Behavioral Models for Predicting Inter-Temporal Choices

Knorr, F. G.; Neukam, P.; Frohner, J. H.; Mohr, H.; Smolka, M. N.; Marxen, M.

10.1101/866285 — neuroscience — Posted on 2019-12-11

1990 Rapid and Inexpensive Preparation of Genome-Wide Nucleosome Footprints from Model and Non-Model Organisms

McKnight, L. E.; Crandall, J. G.; Bailey, T. B.; Banks, O. G.; Orlandi, K. N.; Truong, V. N.; Waddell, G. L.; Wiles, E. T.; Donovan, D. A.; Hansen, S. D.; Selker, E. U.; McKnight, J. N.

10.1101/870659 — genetics — Posted on 2019-12-11

1991 Bacterial Major Vault Protein homologs shed new light on origins of the enigmatic organelle

Sokolskyi, T.

10.1101/872010 — evolutionary biology — Posted on 2019-12-11

1992 HOX paralogs selectively convert binding of ubiquitous transcription factors into tissue-specific patterns of enhancer activation

Bridoux, L.; Zarrineh, P.; Mallen, J.; Phuycharoen, M.; Latorre, V.; Ladam, F.; Losa, M.; Sagerstrom, C.; Mace, K. A.; Rattray, M.; Bobola, N.

10.1101/871640 — developmental biology — Posted on 2019-12-11

1993 Cep57 and Cep57l1 cooperate to recruit the Cep63-Cep152 complex for centriole biogenesis

Zhao, H.; Yang, S.; Duan, X.; Chen, Q.; Li, G.; Huang, Q.; Zhu, X.; Yan, X.

10.1101/842682 — cell biology — Posted on 2019-12-11

1994 The Min system disassembles FtsZ foci and inhibits polar peptidoglycan remodeling in Bacillus subtilis

Yu, Y.; Zhou, J.; Dempwolff, F.; Baker, J.; Kearns, D. B.; Jacobson, S. C.

10.1101/872325 — microbiology — Posted on 2019-12-11

1995 Towards a systematic map of the functional role of protein phosphorylation

Vieitez, C.; Busby, B. P.; Ochoa, D.; Mateus, A.; Galardini, M.; Jawed, A.; Memon, D.; Potel, C. M.; Vonesch, S. C.; Szu Tu, C.; Shahraz, M.; Stein, F.; Steinmetz, L. M.; Savitski, M. M.; Typas, A.; Beltrao, P.

10.1101/872770 — systems biology — Posted on 2019-12-11

1996 On the role of Nav1.7 sodium channels in chronic pain: an experimental and computational study

Capurro, A.; Thornton, J.; Cessac, B.; Armstrong, L.; Sernagor, E.

10.1101/871236 — neuroscience — Posted on 2019-12-11

1997 A Higher Proportion of Craniosynostosis Genes Are Cancer Driver Genes

Misra, S.; Shih, A.; Yan, X.-j.; Li, W.

10.1101/872093 — genetics — Posted on 2019-12-11

1998 Causal role of L-glutamine in sickle cell disease painful crises: a Mendelian randomization analysis

Ilboudo, M. Y. T.; Garrett, M. E.; Bartolucci, P.; Brugnara, C.; Clish, C.; Hirschhorn, J.; Galacteros, F.; Ashley-Koch, A.; Telen, M.; Lettre, G.

10.1101/872358 — genetics — Posted on 2019-12-11

1999 Partitioning environment and space in species-by-site matrices: a comparison of methods for community ecology and macroecology

Viana, D. S.; Keil, P.; Jeliazkov, A.

10.1101/871251 — ecology — Posted on 2019-12-11

2000 The C-terminal domain of Clostridioides difficile TcdC is exposed on the bacterial cell surface

oliveira paiva, A. M.; de Jong, L.; Friggen, A. H.; Smits, W. K.; Corver, J.

10.1101/872283 — microbiology — Posted on 2019-12-11

2001 Deep Learning for RNA Synthetic Biology

Angenent-Mari, N.; Garruss, A.; Soenksen, L. R.; Church, G.; Collins, J.

10.1101/872077 — bioengineering — Posted on 2019-12-11

2002 On the use of calcium deconvolution algorithms in practical contexts

Evans, M.; Petersen, R. D.; Humphries, M. D.

10.1101/871137 — neuroscience — Posted on 2019-12-11

2003 Astrocytic mechanism of glutamate modulation underlying synchronous bursting in cortical cultures

Kumar, R.; Huang, Y.-T.; Chen, C.-C.; Tzeng, S.-F.; Chan, C.-K.

10.1101/870915 — neuroscience — Posted on 2019-12-11

2004 Genetic risk of dementia modifies the impact of obesity on limbic white matter and spatial navigation behavior in cognitively healthy adults.

Mole, J. P.; Fasano, F.; Evans, J.; Sims, R.; Hamilton, D. A.; Kidd, E.; Metzler-Baddeley, C.

10.1101/871160 — neuroscience — Posted on 2019-12-11

2005 Identification of regulators of poly-ADP-ribose polymerase (PARP) inhibitor response through complementary CRISPR knockout and activation screens

Clements, K. E.; Hale, A.; Tolman, N. J.; Nicolae, C. M.; Sharma, A.; Thakar, T.; Liang, X.; Imamura Kawasawa, Y.; Wang, H.-G.; De, S.; Moldovan, G.-L.

10.1101/871970 — molecular biology — Posted on 2019-12-11

2006 Continuous, multidimensional coding of 3D complex tactile stimuli by primary sensory neurons of the vibrissal system

Bush, N. E.; Solla, S. A.; Hartmann, M. J. Z.

10.1101/869255 — neuroscience — Posted on 2019-12-11

2007 Regulation of heterotopic ossification through local inflammatory monocytes in a mouse model of aberrant wound healing

Huber, A. K.; Sorkin, M.; Hwang, C.; Carson, W. F.; Menon, R.; Li, J.; Vasquez, K.; Pagani, C.; Patel, N.; Li, S.; Visser, N.; Niknafs, Y.; Loder, S.; Scola, M.; Nycz, D.; Gallagher, K.; McCauley, L.; Xu, J.; James, A.; Agarwal, S.; Kunkel, S.; Mishina, Y.; Levi, B.

10.1101/871574 — immunology — Posted on 2019-12-11

2008 In vitro induced floral reversion in switchgrass (Panicum Virgatum L.)

Wang, Y.; Xie, K.; Sun, F.; Zhang, C.; Liu, S.; Xi, Y.

10.1101/871152 — developmental biology — Posted on 2019-12-11

2009 Region-specific and dose-specific effects of chronic haloperidol exposure on Ro15-4513 GABA-A receptor binding sites in the rat brain

Peris-Yague, A.; Kiemes, A.; Cotel, M.-C.; Cash, D.; Singh, N.; Vernon, A. C.; Modinos, G.

10.1101/869941 — neuroscience — Posted on 2019-12-11

2010 Mechanism of perceived duration in artificial brains suggests new model of attentional entrainment

Tehrani-Saleh, A.; McAuley, J. D.; Adami, C.

10.1101/870535 — neuroscience — Posted on 2019-12-11

2011 Urodynamic parameters and anesthetic depth vary depending on anesthetic agent (alfaxalone, dexmedetomidine, propofol) at doses necessary to facilitate preclinical testing

Xu, J. J.; Yousuf, Z.; Ouyang, Z.; Kennedy, E.; Lester, P.; Martin, T.; Bruns, T.

10.1101/868398 — physiology — Posted on 2019-12-11

2012 Regional glia-related metabolite levels are higher at older age and scale negatively with visuo-spatial working memory: A cross-sectional proton MR spectroscopy study at 7 tesla on normal cognitive ageing

Lind, A.; Boraxbekk, C.-J.; Petersen, E. T.; Paulson, O. B.; Siebner, H.; Marsman, A.

10.1101/864496 — neuroscience — Posted on 2019-12-11

2013 Pragmatic Language Processing in the Adolescent Brain

Asaridou, S. S.; Demir-Lira, E.; Udden, J. S.; Goldin-Meadow, S.; Small, S. L.

10.1101/871343 — neuroscience — Posted on 2019-12-11

2014 TransINT: an interface-based prediction of membrane protein-protein interactions

Khazen, G.; Issa, T.; Gyulkhandanian, A.; Maroun, R. C.

10.1101/871590 — bioinformatics — Posted on 2019-12-11

2015 ImmuCellAI: a unique method for comprehensive T-cell subsets abundance prediction and its application in cancer immunotherapy

Ya, R. M.; Zhang, Q.; Lei, Q.; Luo, M.; Xie, G. Y.; Wang, X. H.; Guo, A.

10.1101/872184 — bioinformatics — Posted on 2019-12-11

2016 eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants

Thornton, A. M.; Fang, L.; O'Brian, C.; Berger, A. H.; Giannakis, M.; Brooks, A. N.

10.1101/872028 — bioinformatics — Posted on 2019-12-11

2017 Mutagenesis of two homologs ATP Binding cassette protein in tomato by CRISPR/Cas9 provide resistance against the plant parasite Phelipanche aegyptiaca

Bari, V. K.; Nassar, J. A.; Meir, A.; Aly, R.

10.1101/871087 — plant biology — Posted on 2019-12-11

2018 Enhancing Myocardial Repair with CardioClusters

Monsanto, M.; Wang, B.; Ehrenberg, Z.; Echeagaray, O.; White, K.; Alvarez, R.; Fisher, K.; Sengphanith, S.; Muliono, A.; Gude, N.; Sussman, M.

10.1101/759845 — cell biology — Posted on 2019-12-11

2019 Effectiveness of treatments for firework fears in dogs

Riemer, S.

10.1101/663294 — animal behavior and cognition — Posted on 2019-12-11

2020 Competitive Inhibition of Cortisol by Prostaglandins at the Ligand Binding Domain of Glucocorticoid Receptors

Schaper, C.

10.1101/851501 — molecular biology — Posted on 2019-12-11

2021 Comparative analysis of microbial diversity across temperature gradients in hot springs from Yellowstone and Iceland

Podar, P. T.; Yang, Z. K.; Bjornsdottir, S. H.; Podar, M.

10.1101/841700 — microbiology — Posted on 2019-12-11

2022 Can education be personalised using pupils' genetic data?

Morris, T. T.; Davies, N. M.; Davey Smith, G.

10.1101/645218 — genetics — Posted on 2019-12-11

2023 Ectoderm to mesoderm transition by downregulation of actomyosin contractility

Kashkooli, L.; Rozema, D.; Espejo-Ramirez, L.; Lasko, P.; Fagotto, F.

10.1101/870444 — cell biology — Posted on 2019-12-11

2024 Diffusion Weighted Image Co-registration: Investigation of Best Practices

Chen, D. Q.; Dell'Acqua, F.; Rokem, A.; Garyfallidis, E.; Hayes, D. J.; Zhong, J.; Hodaie, M.

10.1101/864108 — neuroscience — Posted on 2019-12-11

2025 A novel cis regulatory element regulates human XIST in CTCF-dependent manner

Shah, R.; Kelkar, A.; Galande, S.

10.1101/871178 — genomics — Posted on 2019-12-11

2026 Guanidine hydrochloride reactivates an ancient septin hetero-oligomer assembly pathway in budding yeast

Johnson, C. R.; Steingesser, M. G.; Weems, A. D.; Khan, A.; Gladfelter, A.; Bertin, A.; McMurray, M. A.

10.1101/744722 — genetics — Posted on 2019-12-11

2027 Field manipulation of competition among hybrids reveals dynamic and highly stable features of a complex fitness landscape driving adaptive radiation

Martin, C. H.; Gould, K.

10.1101/756908 — evolutionary biology — Posted on 2019-12-11

2028 The immunocytokine L19-TNF eradicates Sarcomas in combination with Chemotherapy or with immune check-point inhibitors

Corbellari, R.; Nadal, L.; Villa, A.; Neri, D.; De Luca, R.

10.1101/830406 — cancer biology — Posted on 2019-12-11

2029 Parkinson's disease associated mutation E46K of α-synuclein triggers the formation of a novel fibril structure

Zhao, K.; Li, Y.; Liu, Z.; Long, H.; Zhao, C.; Luo, F.; Sun, Y.; Tao, Y.; Su, X.-d.; Li, D.; Li, X.; Liu, C.

10.1101/870758 — biophysics — Posted on 2019-12-11

2030 A deep neural network approach to predicting clinical outcomes of neuroblastoma patients

Tranchevent, L.-C.; Azuaje, F.; Rajapakse, J. C.

10.1101/750364 — bioinformatics — Posted on 2019-12-11

2031 Microbial single-cell RNA sequencing by split-pool barcoding

Kuchina, A.; Brettner, L. M.; Paleologu, L.; Roco, C. M.; Rosenberg, A. B.; Carignano, A.; Kibler, R.; Hirano, M.; DePaolo, R. W.; Seelig, G.

10.1101/869248 — bioengineering — Posted on 2019-12-11

2032 Inhibiting Mycobacterium tuberculosis CoaBC by targeting a new allosteric site.

Mendes, V.; Green, S. R.; Evans, J. C.; Hess, J.; Blaszczyk, M.; Spry, C.; Bryant, O.; Cory-Wright, J.; Chan, D. S.-H.; Torres, P. H. M.; Wang, Z.; O'Neill, S.; Damerow, S.; Post, J.; Bayliss, T.; Lynch, S. L.; Coyne, A. G.; Ray, P. C.; Abell, C.; Rhee, K. Y.; Boshoff, H. I. M.; Barry, C. E.; Mizrahi, V.; Wyatt, P. G.; Blundell, T. L.

10.1101/870154 — biochemistry — Posted on 2019-12-11

2033 Identification of GABAergic neurons innervating the zebrafish lateral habenula

Ramaswamy, M.; Cheng, R.-K.; Jesuthasan, S. J.

10.1101/870741 — neuroscience — Posted on 2019-12-11

2034 Two forms of Opa1 cooperate to complete fusion of the mitochondrial inner-membrane

Ge, Y.; Shi, X.; Boopathy, S.; McDonald, J.; Smith, A. W.; Chao, L. H.

10.1101/739078 — biophysics — Posted on 2019-12-11

2035 Corruption of the Pearson correlation coefficient by measurement error: estimation, bias, and correction under different error models

Saccenti, E.; Hendriks, M.; Smilde, A.

10.1101/671693 — bioinformatics — Posted on 2019-12-11

2036 Rapid adaptive evolution of scale-eating kinematics to a novel ecological niche

St. John, M. E.; Holzman, R.; Martin, C. H.

10.1101/648451 — animal behavior and cognition — Posted on 2019-12-11

2037 Area 2 of primary somatosensory cortex encodes kinematics of the whole arm

Chowdhury, R. H.; Glaser, J. I.; Miller, L. E.

10.1101/643205 — neuroscience — Posted on 2019-12-11

2038 Molecular Landscape of Anti-Drug Antibodies Reveals the Mechanism of the Immune Response Following Treatment with TNF-alpha Antagonists

Vaisman-Mentesh, A.; Rosenstein, S.; Yavzori, M.; Dror, Y.; Fudim, E.; Ungar, B.; Kopylov, U.; Picard, O.; Kigel, A.; Ben-Horin, S.; Benhar, I.; Wine, Y.

10.1101/509489 — immunology — Posted on 2019-12-11

2039 Spatial domain analysis predicts risk of colorectal cancer recurrence and infers associated tumor microenvironment networks

Uttam, S.; Stern, A. M.; Furman, S.; Pullara, F.; Spagnolo, D.; Nguyen, L.; Gough, A. H.; Sevinsky, C.; Ginty, F.; Taylor, D. L.; Chennubhotla, S. C.

10.1101/635730 — cancer biology — Posted on 2019-12-11

2040 Hormonal balance finely tunes dormancy status in sweet cherry flower buds

Vimont, N.; Schwarzenberg, A.; Domijan, M.; Beauvieux, R.; Arkoun, M.; Jamois, F.; Yvin, J.-C.; Cortijo, S.; Wigge, P. A.; Dirlewanger, E.; Wenden, B.

10.1101/423871 — plant biology — Posted on 2019-12-11

2041 Population Temporal Structure Supplements The Rate Code During Sensorimotor Transformations

Jagadisan, U. K.; Gandhi, N. J.

10.1101/132514 — neuroscience — Posted on 2019-12-11

2042 CoproID predicts the source of coprolites and paleofeces using microbiome composition and host DNA content

Borry, M.; Cordova, B.; Perri, A.; Wibowo, M. C.; Honap, T.; Ko, W. T. J.; Yu, J.; Britton, K.; Flink, L. G.; Power, R. C.; Stuijts, I.; Garcia, D. S.; Hofman, C. A.; Hagan, R. W.; Kagone, T. S.; Meda, N.; Carabin, H.; Jacobson, D.; Reinhard, K.; Lewis, C. M.; Kostic, A.; Jeong, C.; Herbig, A.; Huebner, A.; Warinner, C.

10.1101/871533 — microbiology — Posted on 2019-12-11

2043 Insights into the ligand-free structure of cyclic diguanosine monophosphate I riboswitch of Vibrio cholerae using molecular dynamics simulation

Kumari, P.; Som, A.

10.1101/871194 — bioinformatics — Posted on 2019-12-11

2044 Shotgun metagenomics and metabolomics reveal glyphosate alters the gut microbiome of Sprague-Dawley rats by inhibiting the shikimate pathway

Mesnage, R.; Teixeira, M.; Mandrioli, D.; Falcioni, L.; Ducarmon, Q. R.; Zwittink, R. D.; Amiel, C.; Panoff, J.-M.; Belpoggi, F.; Antoniou, M.

10.1101/870105 — pharmacology and toxicology — Posted on 2019-12-11

2045 Activation of macrophages by lysophosphatidic acid through the lysophosphatidic acid receptor 1 as a novel mechanism in multiple sclerosis pathogenesis.

Fransson, J.; Gomez, A. I.; Romero-Imbroda, J.; Fernandez, O.; Leyva, L.; Rodriguez de Fonseca, F.; Chun, J.; Louapre, C.; Baron Van-Evercooren, A.; Zujovic, V.; Estivill-Torrus, G.; Garcia-Diaz, B.

10.1101/870980 — neuroscience — Posted on 2019-12-11

2046 Characteristics of a novel NMR-based metabolomics platform for dogs

Ottka, C.; Vapalahti, K.; Puurunen, J.; Vahtera, L.; Lohi, H.

10.1101/871285 — molecular biology — Posted on 2019-12-11

2047 An RNA Degradation Complex Required for Spreading and Epigenetic Inheritance of Heterochromatin

Shipkovenska, G.; Durango, A.; Kalocsay, M.; Gygi, S.; Moazed, D.

10.1101/870766 — molecular biology — Posted on 2019-12-11

2048 Exploring Cryptococcus neoformans capsule structure and assembly with a hydroxylamine-armed fluorescent probe

Crawford, C.; Cordero, R. J. B.; Guazzelli, L.; Wear, M. P.; Oscarson, S.; Casadevall, A.

10.1101/871665 — microbiology — Posted on 2019-12-11

2049 UniPath: A uniform approach for pathway and gene-set based analysis of heterogeneity in single-cell epigenome and transcriptome profiles.

Chawla, S.; Samydurai, S.; Kong, S. L.; Wang, Z.; TAM, W. L.; Sengupta, D.; KUMAR, V.

10.1101/864389 — genomics — Posted on 2019-12-11

2050 The dengue virus non-structural protein 1 (NS1) use the scavenger receptor B1 as cell receptor in human hepatic and mosquito cells

Alcala, A. C.; Maravillas, J. L.; Meza, D.; Ramirez, O. T.; Ludert, J. E.; Palomares, L. A.

10.1101/871988 — microbiology — Posted on 2019-12-11

2051 The Euler Characteristic and Topological Phase Transitions in Complex Systems

Amorim, E.; Moreira, R. A.; Santos, F. A. N.

10.1101/871632 — biophysics — Posted on 2019-12-11

2052 Prediction of 8-state protein secondary structures by 1D-Inception and BD-LSTM

Ratul, M. A. R.; Turcotte, M.; Mozaffari, M. H.; Lee, W.

10.1101/871921 — bioinformatics — Posted on 2019-12-11

2053 A stomatal model of anatomical tradeoffs between photosynthesis and pathogen defense

Muir, C. D.

10.1101/871228 — plant biology — Posted on 2019-12-11

2054 Escherichia coli NusG links the lead ribosome with the transcription elongation complex

Washburn, R.; Zuber, P. K.; Sun, M.; Hashem, Y.; Shen, B.; Li, W.; Harvey, S.; Knauer, S. H.; Frank, J.; Gottesman, M. E.

10.1101/871962 — molecular biology — Posted on 2019-12-11

2055 Fate mapping quantifies the dynamics of B cell development and activation throughout life

Verheijen, M.; Rane, S.; Yates, A. J.; Seddon, B.

10.1101/871624 — immunology — Posted on 2019-12-11

2056 Kinship and social organization in Copper Age Europe. A cross-disciplinary analysis of archaeology, DNA, isotopes, and anthropology from two Bell Beaker cemeteries

Sjogren, K.-G.; Heyd, V.; Olalde, I.; Carver, S.; Allentoft, M. E.; Knowles, T.; Kroonen, G.; Pike, A. W.; Schroeter, P.; Brown, K. A.; Robson-Brown, K.; Harrison, R. J.; Bertemes, F.; Reich, D. E.; Kristiansen, K.

10.1101/863944 — genetics — Posted on 2019-12-11

2057 Effects of cLFchimera, a recombinant antimicrobial peptide, on intestinal morphology, microbiota, and gene expression of immune cells and tight junctions in broiler chickens challenged with C. perfringens

Daneshmand, A.; Kermanshahi, H.; Sekhavati, M. H.; Javadmanesh, A.; Ahmadian, M.; Alizadeh, M.; Aldavoodi, A.

10.1101/871467 — pathology — Posted on 2019-12-10

2058 Mitochondrial localization of SESN2

Kovaleva, I. E.; Tokarchuk, A. V.; Zeltuckin, A. O.; Safronov, G.; Evstafieva, A. G.; Dalina, A. A.; Lyamzaev, K.; Chumakov, P. M.; Budanov, A. V.

10.1101/871442 — molecular biology — Posted on 2019-12-10

2059 Acidic pH reduces Vibrio cholerae motility in mucus by weakening flagellar motor torque

Dufour, Y. S.; Nhu, N. T.; Wang, H. J.

10.1101/871475 — microbiology — Posted on 2019-12-10

2060 Dissecting molecular regulatory mechanisms underlying noncoding susceptibility SNPs associated with 19 autoimmune diseases using multi-omics integrative analysis

Chen, X.-F.; Guo, M.-R.; Duan, Y.-Y.; Jiang, F.; Wu, H.; Dong, S.-S.; Thynn, H. N.; Liu, C.-C.; Zhang, L.; Guo, Y.; Yang, T.-L.

10.1101/871384 — immunology — Posted on 2019-12-10

2061 FLS2 is a CDK-like kinase that directly binds IFT70 and is required for proper ciliary disassembly in Chlamydomonas

Zhao, Q.; Li, S.; Shao, S.; Wang, Z.; Pan, J.

10.1101/871376 — cell biology — Posted on 2019-12-10

2062 Repeated exposure to nanosecond high power pulsed microwaves increases cancer incidence in rat

De Seze, R.; Poutriquet, C.; Gamez, C.; Maillot-Marechal, E.; Robidel, F.; Lecomte, A.; Fonta, C.

10.1101/871392 — biophysics — Posted on 2019-12-10

2063 Optimizing an environmental DNA protocol for monitoring threatened Chinook Salmon in the San Francisco Estuary: balancing sensitivity, cost and time.

Sanches, T.; Drauch Scherier, A.

10.1101/871368 — genetics — Posted on 2019-12-10

2064 Voluntary wheel running has no impact on brain and liver mitochondrial DNA copy number or mutation measures in the PolG mouse model of aging

Maclaine, K. D.; Stebbings, K. A.; Llano, D. A.; Rhodes, J. S.

10.1101/871426 — cell biology — Posted on 2019-12-10

2065 Laboratory testing of very low-copper-treated water to prolong pupation and emerging time of mosquito larvae: an alternative method to delay mosquito breeding capability

Reza, M.; Ilmiawati, C.

10.1101/871400 — zoology — Posted on 2019-12-10

2066 Developing political-ecological theory: The need for Many-Task Computing

Haas, T. C.

10.1101/871434 — scientific communication and education — Posted on 2019-12-10

2067 In Situ Processing and Efficient Environmental Detection (iSPEED) of pests and pathogens of trees using point-of-use real-time pcr

Hamelin, A. C.; Stewart, D.; Hrywkiw, K.; Allen, K.; Feau, N.; Bilodeau, G.; Tanguay, P.; Cusson, M.; Hamelin, R. C.

10.1101/871459 — plant biology — Posted on 2019-12-10

2068 High-density genetic linkage map construction and white rot resistance QTL mapping for Vitis based on restriction site-associated DNA sequencing

Su, K.; Guo, Y.; Zhong, W.; Lin, H.; Liu, Z.; Li, K.; Guo, X.

10.1101/726687 — genetics — Posted on 2019-12-10

2069 Microbial residents of the Atlantis Massif's shallow serpentinite subsurface

Motamedi, S.; Orcutt, B.; Früh-Green, G. L.; Twing, K. I.; Pendleton, H. L.; Brazelton, W.

10.1101/870956 — microbiology — Posted on 2019-12-10

2070 NickSeq for genome-wide strand-specific identification of DNA single-strand break sites with single nucleotide resolution

Elacqua, J. J.; Ranu, N.; DiIorio, S. E.; Blainey, P. C.

10.1101/867937 — genomics — Posted on 2019-12-10

2071 The compact genome of Giardia muris reveals important steps in the evolution of intestinal protozoan parasites

Xu, F.; Jimenez-Gonzalez, A.; Einarsson, E.; Astvaldsson, A.; Peirasmaki, D.; Eckmann, L.; Andersson, J. O.; Svärd, S. G.; Jerlström-Hultqvist, J.

10.1101/870949 — evolutionary biology — Posted on 2019-12-10

2072 Characterization of eyes, photoreceptors and opsins in developmental stages of the chaetognath Spadella cephaloptera

Wollesen, T.; Rodriguez Monje, S. V.; Oel, A. P.; Arendt, D.

10.1101/871111 — zoology — Posted on 2019-12-10

2073 Na2CO3-Responsive Photosynthetic and ROS Scavenging Mechanisms in Chloroplasts of Alkaligrass Revealed by Phosphoproteomics

Suo, J.; Zhang, H.; Zhao, Q.; Zhang, N.; Zhang, Y.; Li, Y.; Song, B.; Yu, J.; Cao, J.; Wang, T.; Luo, J.; Guo, L.; Ma, J.; Zhang, X.; She, Y.; Peng, L.; Ma, W.; Guo, S.; Miao, Y.; Chen, S.; Qin, Z.; Dai, S.

10.1101/871046 — plant biology — Posted on 2019-12-10

2074 Mutagenesis of two homologs ATP Binding cassette protein in tomato by CRISPR/Cas9 provide resistance against the plant parasite Phelipanche aegyptiaca

Bari, V. K.; Aly, R.; Nassar, J. A.; Meir, A.

10.1101/871087 — plant biology — Posted on 2019-12-10

2075 Nanomule Peptide-siRNA Conjugate that Traverses the Intact Blood Brain Barrier and Attenuates Stroke

Jefferies, W. A.

10.1101/871186 — pathology — Posted on 2019-12-10

2076 Anti-PD-1 treatment as a neurotherapy to enhance neuronal excitability, synaptic plasticity and memory

Zhao, J.; Ji, R. R.

10.1101/870600 — neuroscience — Posted on 2019-12-10

2077 Quantitative Real-Time PCR assays for species-specific detection and quantification of Baltic Sea spring bloom dinoflagellates

Brink, A. M.; Kremp, A.; Gorokhova, E.

10.1101/871020 — molecular biology — Posted on 2019-12-10

2078 Identification of the C. sordellii lethal toxin receptor elucidates principles of receptor specificity in clostridial toxins

Lee, H.; Beilhartz, G. L.; Kucharska, I.; Raman, S.; Cui, H.; Lam, M.; Rubinstein, J. L.; Schramek, D.; Julien, J.-P.; Melnyk, R.; Taipale, M.

10.1101/871707 — molecular biology — Posted on 2019-12-10

2079 Investigation of skin microbiota reveals Mycobacterium ulcerans-Aspergillus sp. trans-kingdom communication

Hammoudi, N.; Cassagne, C.; Million, M.; Ranque, S.; Kabore, O.; Drancourt, M.; Zingue, D.; Bouam, A.

10.1101/869636 — microbiology — Posted on 2019-12-10

2080 Ulcerative colitis is characterized by amplified acute inflammation with delayed resolution

Wysoczanski, R.; Kendall, A. C.; Motwani, M.; Vega, R.; Rahman, F. Z.; McCartney, S.; Bloom, S. L.; Nicolaou, A.; Gilroy, D. W.; Segal, A. W.; Marks, D. J.

10.1101/870139 — immunology — Posted on 2019-12-10

2081 Overexpression Of Mig-6 In Limb Mesenchyme Leads To Accelerated Osteoarthritis In Mice

Rodrigues Bellini, M.; Pest, M. A.; Jeong, J.-W.; Beier, F.

10.1101/871350 — genetics — Posted on 2019-12-10

2082 Pharmacological and fasting-induced activation of SIRT1/LXRα signaling alleviates diabetes-induced retinopathy.

Hammer, S. S.; Vieira, C. P.; McFarland, D.; Sandler, M.; Levitsky, Y.; Dorweiler, T. F.; Lydic, T.; Asare-Bediako, B.; Adu-Agyeiwaah, Y.; Sielski, M. S.; Dupont, M.; Longhini, A. L.; Calzi, S. L.; Chakraborty, D.; Seigel, G. M.; Proshlyakov, D. A.; Grant, M. B.; Busik, J. V.

10.1101/871822 — cell biology — Posted on 2019-12-10

2083 Comparative proximity biotinylation produces an inventory of RAB18-interactions and implicates RAB18 in cholesterol mobilization

Kiss, R. S.; Chicoine, J.; Sladek, R.; Chen, H.; Pisaturo, A.; Martin, C.; Dale, J. D.; Brudenell, T. A.; Kamath, A.; Wills, J. C.; von Kriegsheim, A.; Nilsson, T.; Sheridan, E.; Handley, M. T.

10.1101/871517 — cell biology — Posted on 2019-12-10

2084 A Highly-ordered and Fail-safe Electrical Network in Cable Bacteria

Bonne, R.; Thiruvallur Eachambadi, R.; Cornelissen, R.; Hidalgo-Martinez, S.; Vangronsveld, J.; Meysman, F. J. R.; Valcke, R.; Cleuren, B.; Manca, J. V.

10.1101/866319 — biophysics — Posted on 2019-12-10

2085 Time and mode of Culicidae evolutionary history

da Silva, A. F.; Machado, L. C.; de Paula, M. B.; Vieira, C. J. d. S. P.; Bronzoni, R. V. d. M.; de Melo-Santos, M. A. V.; Wallau, G. d. L.

10.1101/871145 — evolutionary biology — Posted on 2019-12-10

2086 SpecHap: a fast haplotyping method based on spectral graph theory

Yu, Y.; Chen, L.; Tan, B.; Jia, W.; Li, S.

10.1101/870972 — bioinformatics — Posted on 2019-12-10

2087 iASPP contributes to cortex rigidity, astral microtubule capture and mitotic spindle positioning

Mangon, A.; Salaün, D.; Lala Bouali, M.; Quitard, S.; Isnardon, D.; Audebert, S.; Puech, P.-H.; Verdier-Pinard, P.; Badache, A.

10.1101/870998 — cell biology — Posted on 2019-12-10

2088 The Lon protease links nucleotide metabolism with proteotoxic stress

Zeinert, R. D.; Baniasadi, H.; Tu, B.; Chien, P.

10.1101/870733 — microbiology — Posted on 2019-12-10

2089 Nanopore sequencing reveals U2AF1 S34F-associated full-length isoforms

Soulette, C. M.; Hrabeta-Robinson, E.; Tang, A.; Marin, M. G.; Brooks, A. N.

10.1101/871863 — genomics — Posted on 2019-12-10

2090 Parkinson's disease associated mutation E46K of α-synuclein triggers the formation of a novel fibril structure

Liu, C.; Li, X.; Zhao, K.; Li, Y.; Liu, Z.; Long, H.; Zhao, C.; Luo, F.; Sun, Y.; Tao, Y.; Su, X.-d.; Li, D.

10.1101/870758 — biophysics — Posted on 2019-12-10

2091 Analysis of Mammalian Succinate Dehydrogenase Kinetics and Reactive Oxygen Species Production

Manhas, N.; Duong, Q.; Lee, P.; Bazil, J.

10.1101/870501 — physiology — Posted on 2019-12-10

2092 AUTS2 regulation of synapses for proper synaptic inputs and social communication.

Hori, K.; Yamashiro, K.; Nagai, T.; Shan, W.; Egusa, S. F.; Shimaoka, K.; Go, Y.; Tatsumoto, S.; Yamada, M.; Shiraishi, R.; Kanno, K.; Miyashita, S.; Sakamoto, A.; Abe, M.; Sakimura, K.; Sone, M.; Sohya, K.; Kunugi, H.; Yamada, K.; Hoshino, M.

10.1101/871012 — neuroscience — Posted on 2019-12-10

2093 The Genomic Loci of Specific Human tRNA Genes Exhibit Ageing-Related DNA Hypermethylation

Acton, R. J.; Yuan, W.; Gao, F.; Xia, Y.; Bourne, E.; Wozniak, E.; Bell, J.; Lillycrop, K.; Wang, J.; Dennison, E.; Harvey, N.; Mein, C. A.; Spector, T. D.; Hysi, P. G.; Cooper, C.; Bell, C. G.

10.1101/870352 — genomics — Posted on 2019-12-10

2094 Retrograde Transport of Golgi Enzymes by GOLPH3 Across Maturing Cisternae Regulates Glycan Assembly on Sphingolipids and CellGrowth

Rizzo, R.; Russo, D.; Kurokawa, K.; Sahu, P.; Lombardi, B.; Supino, D.; Zhukovsky, M.; Vocat, A.; Pothukuchi, P.; Kunnathully, V.; Capolupo, L.; Boncompain, G.; Vitagliano, C.; Zito Marino, F.; Aquino, G.; Henklein, P.; Mandrich, L.; Botti, G.; Clausen, H.; Mandel, U.; Yamaji, T.; Hanada, K.; Budillon, A.; Perez, F.; Parashuraman, S.; Hannun, Y. A.; Nakano, A.; D'Angelo, G.; Luini, A.

10.1101/870477 — cell biology — Posted on 2019-12-10

2095 Influence of Strontium on the Physical, Mechanical and In-Vitro Bioactivity of Glass Ionomer Cements

Li, Y.

10.1101/870873 — bioengineering — Posted on 2019-12-10

2096 Diffusion Weighted Image Co-registration: Investigation of Best Practices

Chen, D. Q.; Dell'Acqua, F.; Rokem, A.; Garyfallidis, E.; Hayes, D. J.; Zhong, J.; Hodaie, M.

10.1101/864108 — neuroscience — Posted on 2019-12-10

2097 Selective trans-assembly of human Atg8-family proteins in autophagy-related membrane tethering

Taniguchi, S.; Toyoshima, M.; Takamatsu, T.; Mima, J.

10.1101/870857 — cell biology — Posted on 2019-12-10

2098 A proximity-labeling proteomic approach to investigate invadopodia molecular landscape in breast cancer cells

THUAULT, S.; Mamelonet, C.; SALAMEH, J.; OSTACOLO, K.; CHANEZ, B.; SALAUN, D.; BAUDELET, E.; Audebert, S.; CAMOIN, L.; BADACHE, A.

10.1101/869545 — cancer biology — Posted on 2019-12-10

2099 Identification of GABAergic neurons innervating the zebrafish lateral habenula

Ramaswamy, M.; Cheng, R.-K.; Jesuthasan, S. J.

10.1101/870741 — neuroscience — Posted on 2019-12-10

2100 Neurobehavioural Signatures in Race Car Driving

Rito Lima, I.; Haar, S.; Di Grassi, L.; Faisal, A. A.

10.1101/860056 — neuroscience — Posted on 2019-12-10

2101 Allosteric feed-forward activation of AP-2 via FCHO- BMP2K axis promotes clathrin-mediated endocytosis

Ramesh, S. T.; Kolaparamba, N. V.; Ashok, A. B.; Qathoon, N.; Mohanty, S.; Swain, R. K.; Perunthottathu, U. K.

10.1101/870899 — cell biology — Posted on 2019-12-10

2102 Establishment of a novel method for the production of chimeric mouse embryos using oil droplets.

Imai, H.; Tsuda, S.; Iwamori, T.; Ono, E.

10.1101/870824 — bioengineering — Posted on 2019-12-10

2103 Natural scene statistics predict how humans pool information across space in the estimation of surface tilt

Kim, S.; Burge, J.

10.1101/870618 — neuroscience — Posted on 2019-12-10

2104 Discovery of a Selective, State-Independent Inhibitor of NaV1.7 by Modification of Guanidinium Toxins

Pajouhesh, H.; Beckley, J. T.; Delwig, A.; Hajare, H. S.; Luu, G.; Monteleone, D.; Zhou, X.; Ligutti, J.; Amagasu, S.; Moyer, B. D.; Yeomans, D. C.; Du Bois, J.; Mulcahy, J. V.

10.1101/869206 — neuroscience — Posted on 2019-12-10

2105 RNA-Seq Analysis Illuminates the Early Stages of Plasmodium Liver Infection

Toro-Moreno, M.; Sylvester, K.; Srivastava, T.; Posfai, D.; Derbyshire, E.

10.1101/870030 — microbiology — Posted on 2019-12-10

2106 Antibiotic degradation by commensal microbes shields pathogens

Gjonbalaj, M.; Keith, J. W.; Do, M.; Hohl, T.; Pamer, E.; Becattini, S.

10.1101/870931 — microbiology — Posted on 2019-12-10

2107 Discrete virus factories form in the cytoplasm of cells co-infected with two strains of the segmented dsRNA virus, infectious bursal disease virus (IBDV), that subsequently coalesce

Campbell, E. A.; Gray, A. G.; Wells, J.; Simpson, J.; Hawes, P. C.; Broadbent, A. J.

10.1101/870246 — microbiology — Posted on 2019-12-10

2108 Elevated rates of positive selection drive the evolution of pestiferousness in the Colorado potato beetle (Leptinotarsa decemlineata, Say)

Cohen, Z. P.; Brevik, K.; Chen, Y. H.; Hawthorne, D. J.; Weibel, B. D.; Schoville, S. D.

10.1101/870543 — evolutionary biology — Posted on 2019-12-10

2109 Cytokines and schizophrenia revisited: a two-sample multi-marker Mendelian randomization approach

Ren, H.; Meng, Y.; Zhang, Y.; Wang, Q.; Deng, W.; Ma, X.; Zhao, L.; Li, X.; Wang, Y.; Sham, P. C.; Li, T.

10.1101/870022 — bioinformatics — Posted on 2019-12-10

2110 Human Skeletal Muscle has Large Capacity to Increase Carnosine Content in Response to Beta-Alanine Supplementation. A Systematic Review with Bayesian Individual and Aggregate Data E-Max Model and Meta-Analysis

Rezende, N. S.; Swinton, P. A.; de Oliveira, L. F.; da Silva, R. P.; Silva, V. E.; Nemezio, K.; Yamaguchi, G.; Artioli, G. G.; Gualano, B.; Saunders, B.; Dolan, E.

10.1101/870584 — physiology — Posted on 2019-12-10

2111 VIRAL DELIVERY OF GDNF PROMOTES FUNCTIONAL INTEGRATION OF HUMAN STEM CELL GRAFTS IN PARKINSONS DISEASE

Gantner, C.; de Luzy, I.; Kauhausen, J.; Moriarty, N.; Niclis, J.; Penna, V.; Hunt, C.; Bye, C.; Ermine, C.; Pouton, C.; Kirik, D.; Thompson, L.; Parish, C.

10.1101/870725 — neuroscience — Posted on 2019-12-10

2112 Development and clinical validation of a targeted RNAseq panel (Fusion-STAMP) for diagnostic and predictive gene fusion detection in solid tumors

Nohr, E.; Kunder, C. A.; Jones, C.; Sutton, S.; Fung, E.; Zhu, H.; Feng, S. J.; Gojenola, L.; Bustamante, C.; Zehnder, J. L.; Costa, H. A.

10.1101/870634 — genomics — Posted on 2019-12-10

2113 Clumpy coexistence in phytoplankton: The role of functional similarity in community assembly

Graco-Roza, C.; Segura, A. M.; Kruk, C.; Domingos, P.; Soininen, J.; Marinho, M. M.

10.1101/869966 — ecology — Posted on 2019-12-10

2114 Spatially Varying Trophic Effects of Reservoir-Derived Plankton on Stream Macroinvertebrates Among Heterogeneous Habitats Within Reaches

Takahashi, S.; Takemon, Y.; Omura, T.; Watanabe, K.

10.1101/870717 — ecology — Posted on 2019-12-10

2115 Inhibiting Mycobacterium tuberculosis CoaBC by targeting a new allosteric site.

10.1101/870154 — biochemistry — Posted on 2019-12-10

2116 Pharmacological inhibition of acid sensing ion channel 1a protects the heart from ischemia-reperfusion injury

Redd, M.; Scheuer, S.; Saez, N.; Gao, L.; Hicks, M.; Villanueva, J.; Reichelt, M.; Peart, J.; See Hoe, L.; Chiu, H.; Chen, X.; Sun, Y.; Suen, J.; Maljevic, S.; Thomas, W.; Cuellar-Partida, G.; Fraser, J.; Petrou, S.; King, G.; MacDonald, P.; Palpant, N.

10.1101/869826 — physiology — Posted on 2019-12-10

2117 Adverse caregiving in infancy blunts neural processing of the mother: Translating across species

Opendak, M. M.; Theisen, E.; Blomkvist, A.; Hollis, K.; Lind, T.; Sarro, E.; Lundstrom, J. N.; Tottenham, N.; Dozier, M.; Wilson, D.; Sullivan, R.

10.1101/870261 — neuroscience — Posted on 2019-12-10

2118 Analysis of co-regulated abundance of genes associated with arsenic and phosphate metabolism in Andean Microbial Ecosystems

Saona, L. A.; Valenzuela-Diaz, S.; Kurth, D.; Contreras, M.; Meneses, C.; Castro-Nallar, E.; Farias, M. E.

10.1101/870428 — genomics — Posted on 2019-12-10

2119 Conserved Ark1-related kinases control TORC2 signaling

Alcaide-Gavilan, M.; Banuelos, S.; Lucena, R.; Kellogg, D.

10.1101/870550 — cell biology — Posted on 2019-12-10

2120 Phen2Gene: Rapid Phenotype-Driven Gene Prioritization for Rare Diseases

Zhao, M.; Havrilla, J. M.; Fang, L.; Chen, Y.; Peng, J.; Liu, C.; Wu, C.; Sarmady, M.; Botas, P.; Isla, J.; Lyon, G.; Weng, C.; Wang, K.

10.1101/870527 — bioinformatics — Posted on 2019-12-10

2121 Quantification and Discovery of Acyl-ACPs by LC-MS/MS

Nam, J.-W.; Jenkins, L. M.; Li, J.; Evans, B.; Jaworski, J. G.; Allen, D. K.

10.1101/870485 — biochemistry — Posted on 2019-12-10

2122 Hierarchical assembly of the MLL1 core complex within a biomolecular condensate regulates H3K4 methylation

Namitz, K. E. W.; Tan, S.; Cosgrove, M. S.

10.1101/870667 — biochemistry — Posted on 2019-12-10

2123 The Dopamine Receptor Antagonist TFP Prevents Phenotype Conversion and Improves Survival in Mouse Models of Glioblastoma

Bhat, K.; Saki, M.; Vlashi, E.; Cheng, F.; Duhachek-Muggy, S.; Alli, C.; Yu, G.; Medina, P.; He, L.; Damoiseaux, R.; Pellegrini, M.; Zemke, N. R.; Nghiemphu, P. L.; Cloughesy, T. F.; Liau, L. M.; Kornblum, H.; Pajonk, F.

10.1101/870394 — neuroscience — Posted on 2019-12-10

2124 Effects of nectin-3 misexpression on dendritic spine density during the postnatal development of layer 2/3 cortical neurons

Tomorsky, J. E.; Parker, P. R. L.; Doe, C. Q.; Niell, C. M.

10.1101/870691 — neuroscience — Posted on 2019-12-10

2125 O-GlcNAcylation of small heat shock proteins enhances their anti-amyloid chaperone activity

Balana, A. T.; Levine, P. M.; Mukherjee, S.; Pedowitz, N. J.; Moon, S. P.; Takahashi, T. T.; Becker, C. F. W.; Pratt, M. R.

10.1101/869909 — biochemistry — Posted on 2019-12-10

2126 The regulatory landscape of early maize inflorescence development

Parvathaneni, R. K.; Bertolini, E.; Shamimuzzaman, M.; Vera, D.; Lung, P.-Y.; Rice, B. R.; Brown, P. J.; Lipka, A. E.; Bass, H. W.; Eveland, A. L.

10.1101/870378 — plant biology — Posted on 2019-12-10

2127 Graph Embedding Method Based Genetical Trajectory Reveals Migration History Among East Asians

Wei, Z.; Chang, C.-W.; Luo, V.; Bian, B.; Ding, X.

10.1101/870253 — genetics — Posted on 2019-12-10

2128 Extrinsic cues cooperate with intrinsic temporal factors to increase neuronal diversity

Rossi, A. M.; Desplan, C.

10.1101/870493 — developmental biology — Posted on 2019-12-10

2129 Mitochondrial translation and dynamics synergistically extend lifespan in C. elegans through HLH-30

Liu, Y.; McIntyre, R.; Janssens, G.; Williams, E.; Lan, J.; van Veen, H.; van der Wel, N.; Mair, W. B.; Aebersold, R.; MacInnes, A.; Houtkooper, R.

10.1101/871079 — cell biology — Posted on 2019-12-10

2130 A novel mouse model designed for studying cholangiocarcinoma tumorigenesis uncovers a role for a SOX17-Tensin 4 pathway

Di-Luoffo, M.; Pirenne, S.; Saandi, T.; Loriot, A.; Gerard, C.; Dauguet, N.; Lamoline, F.; Konobrocka, K.; De Greef, V.; Komuta, M.; Jacquemin, P.; Lemaigre, F. P.

10.1101/870212 — cancer biology — Posted on 2019-12-10

2131 How tasks change whole-brain functional organization to reveal brain-phenotype relationships

Greene, A. S.; Gao, S.; Noble, S.; Scheinost, D.; Constable, T.

10.1101/870287 — neuroscience — Posted on 2019-12-10

2132 Alcohol intake triggers aberrant synaptic pruning leading to synapse loss and anxiety-like behavior

Socodato, R.; Henriques, J. F.; Portugal, C. C.; Almeida, T. O.; Tedim-Moreira, J.; Alves, R. L.; Canedo, T.; Silva, C.; Magalhães, A.; Summavielle, T.; Relvas, J. B.

10.1101/870279 — neuroscience — Posted on 2019-12-10

2133 Chromosomal length reference assembly for Diaphorina citri using single-molecule sequencing and Hi-C proximity ligation with manually curated genes in developmental, structural and immune pathways

Hosmani, P. S.; Flores-Gonzalez, M.; Shippy, T.; Vosburg, C.; Massimino, C.; Tank, W.; Reynolds, M.; Tamayo, B.; Miller, S.; Norus, J.; Kercher, K.; Grace, B.; Jernigan, M.; Harper, D.; Adkins, S.; DeLaFlor, Y.; Paris, T.; Vandervoort, S.; Adams, R.; Norman, S.; Ventura, J.; Perry, M.; Weirauch, M.; Benoit, J.; Hunter, W.; Wiersma-Koch, H.; D'elia, T.; Brown, S. J.; Mueller, L.; Saha, S.

10.1101/869685 — genomics — Posted on 2019-12-10

2134 Effectiveness of topical antibiotics in treating corals affected by Stony Coral Tissue Loss Disease

Neely, K. L.; Macaulay, K. A.; Hower, E. K.; Dobler, M. A.

10.1101/870402 — ecology — Posted on 2019-12-10

2135 Regulating lipid composition rationalizes acyl-tail saturation homeostasis in ectotherms

Girard, M.; Bereau, T.

10.1101/870063 — biophysics — Posted on 2019-12-10

2136 EcDBS1R6: A new broad-spectrum cationic antibacterial peptide derived from a signal peptide sequence

Porto, W. F.; Irazazabal, L. N.; Humblot, V.; Haney, E. F.; Ribeiro, S. M.; Hancock, R. E.; Ladram, A.; Franco, O. L.

10.1101/869867 — bioinformatics — Posted on 2019-12-10

2137 tRNA fragments (tRFs) populations analysis in mutants affecting tRNAs processing and tRNA methylation

Molla-Herman, A.; Angelova, M. T.; Carre, C.; Antoniewski, C.; Huynh, J.-R.

10.1101/869891 — bioinformatics — Posted on 2019-12-10

2138 Sequence-to-function deep learning frameworks for synthetic biology

Valeri, J. A.; Collins, K. M.; Lepe, B. A.; Lu, T. K.; Camacho, D. M.

10.1101/870055 — synthetic biology — Posted on 2019-12-10

2139 Analytical solution of linearized equations of the Morris-Lecar neuron model at large constant stimulation

Paraskevov, A.; Zemskova, T.

10.1101/869875 — neuroscience — Posted on 2019-12-10

2140 THE ROLE OF CENTRAL AMYGDALA CORTICOTROPIN-RELEASING FACTOR IN PREDATOR ODOR STRESS-INDUCED AVOIDANCE BEHAVIOR AND ESCALATED ALCOHOL DRINKING IN RATS

Weera, M. M.; Schreiber, A. L.; Avegno, E. M.; Gilpin, N. W.

10.1101/870386 — neuroscience — Posted on 2019-12-10

2141 A mean-field approach to the dynamics of networks of complex neurons, from nonlinear Integrate-and-Fire to Hodgkin-Huxley models

Carlu, M.; Chehab, O.; Dalla Porta, L.; Depannemaecker, D.; Herice, C.; Jedynak, M.; Koksal Ersoz, E.; Muratore, P.; Souihel, S.; Capone, C.; Zerlaut, Y.; Destexhe, A.; di Volo, M.

10.1101/870345 — neuroscience — Posted on 2019-12-10

2142 Evaluation of MALDI-ToF Mass Spectrometry for Rapid Detection of Cereulide from Bacillus cereus Cultures

Doellinger, J.; Schneider, A.; Stark, T.; Ehling-Schulz, M.; Lasch, P.

10.1101/869958 — microbiology — Posted on 2019-12-10

2143 Identification of Microorganisms by Liquid Chromatography-Mass Spectrometry (LC-MS1) and in silico Peptide Mass Data

Lasch, P.; Schneider, A.; Blumenscheit, C.; Doellinger, J.

10.1101/870089 — microbiology — Posted on 2019-12-10

2144 Cultivation and characterization of human midbrain organoids in sensor integrated microfluidic chips

Spitz, S.; Zanetti, C.; Bolognin, S.; Muwanigwa, M. N.; Smits, L. M.; Berger, E.; Jordan, C.; Harasek, M.; Schwamborn, J. C.; Ertl, P.

10.1101/869701 — bioengineering — Posted on 2019-12-10

2145 Natural transformation of the filamentous cyanobacterium Phormidium lacuna

Nies, F.; Mielke, M.; Pochert, J.; Lamparter, T.

10.1101/870006 — microbiology — Posted on 2019-12-10

2146 Reconciling author names in taxonomic and publication databases

Page, R. D. M.

10.1101/870170 — bioinformatics — Posted on 2019-12-10

2147 Sex differences in traumatic stress reactivity of rats with a history of alcohol drinking

Albrechet-Souza, L.; Schratz, C. L.; Gilpin, N. W.

10.1101/869990 — animal behavior and cognition — Posted on 2019-12-10

2148 Effective potential reveals evolutionary trajectories in complex fitness landscapes

Smerlak, M.

10.1101/869883 — evolutionary biology — Posted on 2019-12-10

2149 GIV-Kindlin interaction is required for Kindlin-Mediated Integrin Recognition and Activation

Rohena, C.; Kalogriopoulos, N.; Rajapakse, N.; Roy, S.; Lopez-Sanchez, I.; Ablack, J.; Sahoo, D.; Ghosh, P.

10.1101/870113 — cell biology — Posted on 2019-12-10

2150 Integrating healthcare and research genetic data empowers the discovery of 49 novel developmental disorders

Kaplanis, J.; Samocha, K. E.; Wiel, L.; Zhang, Z.; Arvai, K.; Eberhardt, R.; Gallone, G.; Lelieveld, S. H.; Martin, H.; McRae, J.; Short, P.; Torene, R.; de Boer, E.; Danecek, P.; Gardner, E. J.; Huang, N.; Lord, J.; Martincorena, I.; Pfundt, R.; Reijnders, M.; Yeung, A.; Yntema, H.; DDD study, ; Vissers, L.; Juusola, J.; Wright, C.; Brunner, H.; Firth, H. V.; Fitzpatrick, D. R.; Barrett, J. C.; Hurles, M. E.; Gilissen, C.; Retterer, K.

10.1101/797787 — genomics — Posted on 2019-12-10

2151 Detection of active Granzyme A in NK92 cells with fluorescent activity-based probe

Kolt, S.; Janiszewski, T.; Kaiserman, D.; Modrzycka, S.; Snipas, S. S.; Salvesen, G.; Drag, M.; Bird, P. I.; Kasperkiewicz, P.

10.1101/869149 — biochemistry — Posted on 2019-12-10

2152 Phantom auditory perception (tinnitus) is characterised by stronger anticipatory auditory predictions

Partyka, M.; Demarchi, G.; Roesch, S.; Suess, N.; Sedley, W.; Schlee, W.; Weisz, N.

10.1101/869842 — neuroscience — Posted on 2019-12-10

2153 Thousands of missing variants in the UK BioBankare recoverable by genome realignment

Jia, T.; Munson, B.; Lango Allen, H.; Ideker, T.; Majithia, A. R.

10.1101/868570 — genetics — Posted on 2019-12-10

2154 Hat1-Dependent Lysine Acetylation Targets Diverse Cellular Functions

Agudelo Garcia, P. A.; Nagarajan, P.; Parthun, M.

10.1101/825539 — biochemistry — Posted on 2019-12-10

2155 Design and analysis of CRISPR-based underdominance toxin-antidote gene drives

Champer, J.; Champer, S. E.; Kim, I.; Clark, A. G.; Messer, P. W.

10.1101/861435 — genetics — Posted on 2019-12-10

2156 Equivalent Change Enrichment Analysis: Assessing Equivalent and Inverse Change in Biological Pathways between Diverse Experiments

Thompson, J. A.; Koestler, D. C.

10.1101/586875 — bioinformatics — Posted on 2019-12-10

2157 Validation of Serum Neurofilament Light Chain as a Biomarker of Parkinson's Disease Progression

Mollenhauer, B.; Dakna, M.; Liu, T.-Y.; Galasko, D.; Foroud, T.; Zetterberg, H.; Schade, S.; Gera, R.; Wang, W.; Gao, F.; Kruse, N.; Frasier, M.; Chahine, L.; Coffey, C. S.; Singleton, A. B.; Simuni, T.; Weintraub, D.; Seibyl, J.; Toga, A. W.; Tanner, C. M.; Kieburtz, K.; Marek, K.; Siderowf, A.; Cedarbaum, J. M.; Hutten, S. J.; Trenkwalder, C.; Graham, D.

10.1101/762237 — neuroscience — Posted on 2019-12-10

2158 Priors and Payoffs in Confidence Judgments

Locke, S. M.; Gaffin-Cahn, E.; Hosseinizaveh, N.; Mamassian, P.; Landy, M. S.

10.1101/703082 — neuroscience — Posted on 2019-12-10

2159 An Event-Related Potential Study of Onset Primacy in Visual Change Detection

Van Pelt, J.; Donaldson, M. J.; Robinson, J.; Johnston, P.; Yamamoto, N.

10.1101/539932 — neuroscience — Posted on 2019-12-10

2160 A common pattern of influenza A virus single cell gene expression heterogeneity governs the innate antiviral response to infection

Vera, J. C.; Sun, J.; Lin, Y. T.; Drnevich, J.; Ke, R.; Brooke, C. B.

10.1101/858373 — microbiology — Posted on 2019-12-10

2161 Probabilistic Cause-of-disease Assignment using Case-control Diagnostic Tests: A Hierarchical Bayesian Latent Variable Regression Approach

Wu, Z.; Chen, I.

10.1101/672808 — epidemiology — Posted on 2019-12-10

2162 A novel cis regulatory element regulates human XIST in CTCF-dependent manner

Galande, S.; Shah, R.; Kelkar, A.

10.1101/871178 — molecular biology — Posted on 2019-12-10

2163 T-loops Refold after Telomerase Extension and Unfold Again at Late S/G2 for C-strand Fill-in

Shay, J.; Mak, S.; Chow, T. T.; Smiraldo, P.; Wright, W.

10.1101/869982 — molecular biology — Posted on 2019-12-10

2164 Ribosome recycling factor ABCE1 depletion inhibits nonsense-mediated mRNA decay by promoting stop codon readthrough

Annibaldis, G.; Dreos, R.; Domanski, M.; Carl, S.; Muhlemann, O.

10.1101/870097 — molecular biology — Posted on 2019-12-10

2165 New observations on non-coding RNAs involved in the dual translation system in zebrafish development.

Breit, T. M.; Pagano, J. F. B.; van der Jagt, P. L.; Mittring, E.; Ensik, W. A.; vanOlst, M.; van Leeuwen, S.; De Leeuw, W. C.; Nehrdich, U.; Spaink, H. P.; Rauwerda, H.; Dekker, R. J.

10.1101/869651 — developmental biology — Posted on 2019-12-10

2166 Ectoderm to mesoderm transition by downregulation of actomyosin contractility

Kashkooli, L.; Rozema, D.; Espejo-Ramirez, L.; Lasko, P.; Fagotto, F.

10.1101/870444 — cell biology — Posted on 2019-12-10

2167 Structural analysis of mycobacterial homoserine transacetylases central to methionine biosynthesis reveals druggable active site

Chaton, C. T.; Rodriguez, E. S.; Reed, R. W.; Li, J.; Kenner, C. W.; Korotkov, K. V.

10.1101/808071 — biochemistry — Posted on 2019-12-10

2168 A non-mosaic humanized mouse model of Down syndrome, trisomy of the long arm of human chromosome 21 in mouse chromosome background

Kazuki, Y.; Gao, F.; Li, Y.; Moyer, A.; Devenney, B.; Hiramatsu, K.; Miyagawa-Tomita, S.; Abe, S.; Kazuki, K.; Kajitani, N.; Uno, N.; Takehara, S.; Takiguchi, M.; Yamakawa, M.; Hasegawa, A.; Shimizu, R.; Matsukura, S.; Noda, N.; Ogonuki, N.; Inoue, K.; Matoba, S.; Ogura, A.; Florea, L. D.; Savonenko, A.; Xiao, M.; Wu, D.; Batista, D.; Yang, J.; Qiu, Z.; Singh, N.; Richstemeier, J.; Takeuchi, T.; Oshimura, M.; Reeves, R. H.

10.1101/862433 — genetics — Posted on 2019-12-10

2169 A Pan-Cancer assessment of alterations of ULK1 kinase, an upstream regulator of autophagy

Kumar, M.; Papaleo, E.

10.1101/702522 — bioinformatics — Posted on 2019-12-10

2170 Workshops increase invasive species reports to EDDMapS in the Mid-Atlantic United States

Wallace, R. D.; Bargeron, C. T.; Swearingen, J.; LaForest, J. H.; Moorhead, D. J.; Luo, X.

10.1101/620138 — scientific communication and education — Posted on 2019-12-10

2171 Combining Crowdsourcing and Deep Learning to Assess Public Opinion on CRISPR-Cas9

Muller, M.; Schneider, M.; Salathe, M.; Vayena, E.

10.1101/802454 — scientific communication and education — Posted on 2019-12-10

2172 Dietary restriction transforms the protein sulfhydrome in a tissue-specific and cystathionine γ-lyase-dependent manner

Bithi, N.; Link, C.; Wang, R.; Willard, B.; Hine, C.

10.1101/869271 — physiology — Posted on 2019-12-10

2173 Feature-specific patterns of attention and functional connectivity in human visual cortex

Wailes-Newson, K.; Morland, A. B.; Vernon, R. J. W.; Wade, A. R.

10.1101/869552 — neuroscience — Posted on 2019-12-10

2174 Depurination of colibactin-derived interstrand cross-links.

Xue, M.; Wernke, K.; Herzon, S.

10.1101/869313 — microbiology — Posted on 2019-12-10

2175 Serum level of High-density lipoprotein particles are independently associated with long-term prognosis in patients with coronary artery disease: The GENES study

Duparc, T.; Ruidavets, J.-B.; Genoux, A.; Ingueneau, C.; Najib, S.; Ferrieres, J.; Perret, B.; Martinez, L. O.

10.1101/676122 — epidemiology — Posted on 2019-12-10

2176 Cell motion-coordinated fibrillar assembly of soluble collagen I to promote MDCK cell branching formation

Wang, J.; Guo, J.; Che, B.; Ouyang, M.; Deng, L.

10.1101/869438 — biophysics — Posted on 2019-12-10

2177 Comparative analysis of novel MGISEQ-2000 sequencing platform vs Illumina HiSeq 2500 for whole-genome sequencing

Korostin, D.; Kulemin, N.; Naumov, V.; Belova, V.; Kwon, D.; Gorbachev, A.

10.1101/577080 — genomics — Posted on 2019-12-10

2178 Comparative genomic analysis of Cristatella mucedo provides insights into Bryozoan evolution and nervous system function

Starunov, V. V.; Predeus, A. V.; Barbitoff, Y. A.; Kutyumov, V. A.; Maltseva, A. L.; Vodiasova, E. A.; Kohn, A. B.; Moroz, L. L.; Ostrovsky, A. N.

10.1101/869792 — genomics — Posted on 2019-12-10

2179 Deletion of a conserved zebrafish Gata2 enhancer impairs haemogenic endothelium programming and adult haematopoiesis

Dobrzycki, T.; Mahony, C. B.; Krecsmarik, M.; Koyunlar, C.; Rispoli, R.; Peulen-Zink, J.; Gussinklo, K.; Fedlaoui, B.; de Pater, E.; Patient, R.; Monteiro, R.

10.1101/516203 — developmental biology — Posted on 2019-12-10

2180 Genomic prediction using low density marker panels in aquaculture: performance across species, traits, and genotyping platforms

Kriaridou, C.; Tsairidou, S.; Houston, R. D.; Robledo, D.

10.1101/869628 — genetics — Posted on 2019-12-10

2181 Global Bee Decline

Zattara, E. E.; Aizen, M. A.

10.1101/869784 — ecology — Posted on 2019-12-10

2182 Neural Correlates of Working Memory Training: Evidence for Plasticity in Older Adults

Iordan, A. D.; Cooke, K. A.; Moored, K. D.; Katz, B.; Buschkuehl, M.; Jaeggi, S. M.; Polk, T. A.; Peltier, S. J.; Jonides, J.; Reuter-Lorenz, P. A.

10.1101/869164 — neuroscience — Posted on 2019-12-10

2183 Imaging real-time tactile interaction with two-person dual-coil fMRI

Renvall, V.; Kauramaki, J.; Malinen, S.; Hari, R.; Nummenmaa, L.

10.1101/861252 — neuroscience — Posted on 2019-12-10

2184 TBK1 regulates autophagic clearance of soluble mutant huntingtin and inhibits aggregation/toxicity in different models of Huntington's disease

Hegde, R. N.; Chiki, A.; Petricca, L.; Martufi, P.; Arbez, N.; Mouchiroud, L.; Auwerx, J.; Landles, C.; Bates, G. P.; Singh-Bains, M. K.; Curtis, M. A.; Faull, R. L. M.; Ross, C. A.; Caricasole, A.; Lashuel, H. A.

10.1101/869586 — neuroscience — Posted on 2019-12-10

2185 Decoding of emotion expression in the face, body and voice reveals sensory modality specific representations.

Vaessen, M.; van de Heijden, K.; de Gelder, B.

10.1101/869578 — neuroscience — Posted on 2019-12-10

2186 Dorsal Premotor Cortex Involved in Hand Gesture Preparation in Macaques

Sun, G.; Zhang, S.; Wang, R.; Hao, Y.; Chen, W.; Zheng, X.

10.1101/869354 — animal behavior and cognition — Posted on 2019-12-10

2187 Characterization and rescue by oxytocin of an atypical thermo-sensory reactivity in neonatal mice lacking the autism-associated gene Magel2.

Caccialupi Da Prato, L.; Abdallah, D.; Point, V.; Schaller, F.; Montheil, A.; Pallesi-Pocachard, E.; Canaan, S.; Gaiarsa, J.-L.; Muscatelli, F.; Matarazzo, V.

10.1101/869487 — neuroscience — Posted on 2019-12-10

2188 Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms

Duarte, D. P.; Lamontanara, A. J.; La Sala, G.; Jeong, S.; Sohn, Y.-K.; Panjkovich, A.; Georgeon, S.; Kukenshoner, T.; Marcaida, M. J.; Pojer, F.; De Vivo, M.; Svergun, D.; Kim, H.-S.; Dal Peraro, M.; Hantschel, O.

10.1101/862276 — cancer biology — Posted on 2019-12-10

2189 AdaReg: Data Adaptive Robust Estimation in Linear Regression with Application in GTEx Gene Expressions

Wang, M.; Jiang, L.; Snyder, M. P.

10.1101/869362 — bioinformatics — Posted on 2019-12-10

2190 Designing real novel proteins using deep graph neural networks

Strokach, A.; Becerra, D.; Corbi-Verge, C.; Perez-Riba, A.; Kim, P. M.

10.1101/868935 — bioinformatics — Posted on 2019-12-10

2191 Choroid-resident macrophages maintain local vasculature and RPE integrity and spontaneously regenerate following depletion

Yang, X.; Zhao, L.; Campos, M. M.; Abu-Asab, M.; Ortolan, D.; Hotaling, N.; Bharti, K.; Wong, W. T.

10.1101/868430 — immunology — Posted on 2019-12-10

2192 Draft Genomes of two Artocarpus plants, Jackfruit (A. heterophyllus) and Breadfruit (A. altilis)

Sahu, S. K.; Liu, M.; Yssel, A.; Kariba, R.; Jiang, S.; Song, B.; Muthemba, S.; Hendre, P. S.; Jamnadass, R.; Kao, S.-M.; Featherston, J.; Zerega, N. J. C.; Xu, X.; Yang, H.; Deynze, A. V.; Van de Peer, Y.; Liu, X.; Liu, H.

10.1101/869339 — genomics — Posted on 2019-12-10

2193 Microbial single-cell RNA sequencing by split-pool barcoding

Kuchina, A.; Brettner, L. M.; Paleologu, L.; Roco, C. M.; Rosenberg, A. B.; Carignano, A.; Kibler, R.; Hirano, M.; DePaolo, R. W.; Seelig, G.

10.1101/869248 — bioengineering — Posted on 2019-12-10

2194 Polyandry and Paternity influence disease resistance in a eusocial wasp - support for the pathogen parasite hypothesis

Saga, T.; Okuno, M.; Loope, K. J.; Tsuchida, K.; Ohbayashi, K.; Shimada, M.; Okada, Y.

10.1101/869537 — animal behavior and cognition — Posted on 2019-12-10

2195 Fibroblast growth factor-2 prevents synaptic pathology in minimal hepatic encephalopathy via NRG1/ErbB4 signaling

Ding, S.; wang, J.; Zhuge, W.; Lu, X.; You, R.; Liu, L.; Yu, H.; Ye, Y.; Wang, X.; Zhuge, Q.

10.1101/869503 — neuroscience — Posted on 2019-12-10

2196 Differential rapid plasticity in auditory and visual responses in the primarily multisensory orbitofrontal cortex

Sharma, S.; Bandyopadhyay, S.

10.1101/869446 — neuroscience — Posted on 2019-12-10

2197 Identification of Acinetobacter baumannii loci for capsular polysaccharide (KL) and lipooligosaccharide outer core (OCL) synthesis in genome assemblies using curated reference databases compatible with Kaptive

Wyres, K. L.; Cahill, S. M.; Holt, K. E.; Hall, R. M.; Kenyon, J. J.

10.1101/869370 — microbiology — Posted on 2019-12-10

2198 Genome compartmentalization predates species divergence in the plant pathogen genus Zymoseptoria

Feurtey, A.; Lorrain, C.; Croll, D.; Eschenbrenner, C.; Freitag, M.; Habig, M.; Haueisen, J.; Moller, M.; Schotanus, K.; Holtgrewe Stukenbrock, E.

10.1101/864561 — genomics — Posted on 2019-12-10

2199 Transcriptome analysis of Tartary buckwheat revealed differentially expressed genes in salt pathway

Song, J.-N.; Liu, X.-H.; Wang, Y.-Q.; Yang, H.-B.

10.1101/869263 — genomics — Posted on 2019-12-10

2200 Phage steering of antibiotic-resistance evolution in the bacterial pathogen Pseudomonas aeruginosa

Gurney, J.; Pradier, L.; Griffin, J. S.; Gougat-Barbera, C.; Chan, B. K.; Turner, P. E.; Kaltz, O.; Hochberg, M. E.

10.1101/868661 — evolutionary biology — Posted on 2019-12-10

2201 Rapamycin rejuvenates oral health in aging mice

An, J. Y.; Kerns, K. A.; Ouellette, A.; Robinson, L.; Morris, D.; Kaczorowski, C.; Park, S.-I.; Mekvanich, T.; Kang, A.; McLean, J. S.; Cox, T.; Kaeberlein, M.

10.1101/861369 — pathology — Posted on 2019-12-10

2202 A data-driven framework for the selection and validation of digital health metrics: use-case in neurological sensorimotor impairments

Kanzler, C. M.; Rinderknecht, M. D.; Schwarz, A.; Lamers, I.; Gagnon, C.; Held, J.; Feys, P.; Luft, A. R.; Gassert, R.; Lambercy, O.

10.1101/544601 — neuroscience — Posted on 2019-12-10

2203 BigBrain 3D atlas of cortical layers: cortical and laminar thickness gradients diverge in sensory and motor cortices

Wagstyl, K.; Larocque, S.; Cucurull, G.; Lepage, C.; Cohen, J. P.; Bludau, S.; Palomero-Gallagher, N.; Lewis, L. B.; Funck, T.; Spitzer, H.; Dicksheid, T.; Fletcher, P. C.; Romero, A.; Zilles, K.; Amunts, K.; Bengio, Y.; Evans, A. C.

10.1101/580597 — neuroscience — Posted on 2019-12-10

2204 Exploring the Links between Specific Depression Symptoms and Brain Structure: A Network Study

Hilland, E.; Landro, N. I.; Kraft, B.; Tamnes, C. K.; Fried, E. I.; Maglanoc, L. A.; Jonassen, R.

10.1101/762609 — neuroscience — Posted on 2019-12-10

2205 WHISKiT Physics: A three-dimensional mechanical model of the rat vibrissal array

Zweifel, N. O.; Bush, N. E.; Abraham, I.; Murphey, T. D.; Hartmann, M. J.

10.1101/862839 — neuroscience — Posted on 2019-12-10

2206 LandScape: a web application for interactive genomic summary visualization

Jia, W.; Li, H.; Li, S.; Li, S.

10.1101/866087 — bioinformatics — Posted on 2019-12-10

2207 Crowding Reveals Fundamental Differences in Local vs. Global Processing in Humans and Machines

Doerig, A.; Bornet, A.; Choung, O. H.; Herzog, M. H.

10.1101/744268 — neuroscience — Posted on 2019-12-10

2208 Developing synergistic drug combinations to restore antibiotic sensitivity in drug-resistant Mycobacterium tuberculosis

Omollo, C. O.; Singh, V.; Kigondu, E.; Wasuna, A.; Agarwal, P.; Moosa, A.; Ioerger, T. R.; Mizrahi, V.; Chibale, K.; Warner, D. F.

10.1101/860288 — microbiology — Posted on 2019-12-10

2209 CHANging Consciousness Epistemically (CHANCE): An empirical method to convert the subjective content of consciousness into scientific data

Tanaka, D. H.; Tanabe, T.

10.1101/495523 — neuroscience — Posted on 2019-12-10

2210 TrpML-mediated astrocyte microdomain Ca2+ transients regulate astrocyte-tracheal interactions in CNS

Ma, Z.; Freeman, M. R.

10.1101/865659 — neuroscience — Posted on 2019-12-10

2211 Episodic memory retrieval success is associated with rapid replay of episode content

Wimmer, G. E.; Liu, Y.; Vehar, N.; Behrens, T. E.; Dolan, R. J.

10.1101/758185 — neuroscience — Posted on 2019-12-10

2212 Understanding requires tracking: noise and knowledge interact in bilingual comprehension

Blanco-Elorrieta, E.; Ding, N.; Pylkkanen, L.; Poeppel, D.

10.1101/609628 — neuroscience — Posted on 2019-12-10

2213 The effects of arbuscular mycorrhizal fungi (AMF) and Rhizophagus irregularis on soil microorganisms assessed by metatranscriptomics and metaproteomics

Lammel, D.; Meierhofer, D.; Johnston, P. R.; Mbedi, S.; Rillig, M. C.

10.1101/860932 — ecology — Posted on 2019-12-10

2214 Coexistence of fast and slow gamma oscillations in one population of inhibitory spiking neurons

Bi, H.; Segneri, M.; di Volo, M.; Torcini, A.

10.1101/687624 — neuroscience — Posted on 2019-12-10

2215 A common model explaining flexible decision making, grid fields and cognitive control

Piray, P.; Daw, N. D.

10.1101/856849 — neuroscience — Posted on 2019-12-10

2216 Novel cyclic peptides in seed of Annona muricata are ribosomally synthesised

Fisher, M. F.; Zhang, J.; Berkowitz, O.; Whelan, J.; Mylne, J. S.

10.1101/647552 — biochemistry — Posted on 2019-12-10

2217 Deep Learning provides exceptional accuracy to ECoG-based Functional Language Mapping for epilepsy surgery

RaviPrakash, H.; Korostenskaja, M.; Castillo, E. M.; Lee, K. H.; Salinas, C. M.; Baumgartner, J.; Anwar, S. M.; Spampinato, C.; Bagci, U.

10.1101/497644 — neuroscience — Posted on 2019-12-10

2218 Reporter assays for Ebola virus nucleoprotein oligomerization, virion-like particle budding, and minigenome activity reveal the importance of nucleoprotein amino acid position 111

Lin, A. E.; Diehl, W. E.; Cai, Y.; Finch, C. L.; Akusobi, C.; Kirchdoerfer, R. N.; Bollinger, L.; Schaffner, S. F.; Brown, E. A.; Saphire, E. O.; Andersen, K. G.; Kuhn, J. H.; Luban, J.; Sabeti, P. C.

10.1101/454314 — microbiology — Posted on 2019-12-10

2219 A DNA-guided Argonaute Protein Functions in DNA Replication in Thermus thermophilus

Jolly, S. M.; Gainetdinov, I.; Jouravleva, K.; Zhang, H.; Strittmatter, L.; Hendricks, G. M.; Dhabaria, A.; Ueberheide, B.; Zamore, P.

10.1101/869172 — microbiology — Posted on 2019-12-09

2220 Dynamic relocalization of the cytosolic type III secretion system components ensures specific protein secretion

Wimmi, S.; Balinovic, A.; Jeckel, H.; Selinger, L.; Lampaki, D.; Eisemann, E.; Meuskens, I.; Linke, D.; Drescher, K.; Endesfelder, U.; Diepold, A.

10.1101/869214 — microbiology — Posted on 2019-12-09

2221 Establishment Process of a Magic Trait Allele subject to Both Divergent Selection and Assortative Mating

Sakamoto, T.; Innan, H.

10.1101/869198 — evolutionary biology — Posted on 2019-12-09

2222 Quantifying exploration in reward-based motor learning

van Mastrigt, N. M.; Smeets, J. B. J.; van der Kooij, K.

10.1101/869735 — neuroscience — Posted on 2019-12-09

2223 Opposing patterns of abnormal D1 and D2 receptor dependent cortico-striatal plasticity explain increased risk taking in patients with DYT1 dystonia

Gilbertson, T.; Arkadir, D.; Steele, D.

10.1101/869743 — neuroscience — Posted on 2019-12-09

2224 Prevalence of pulmonary tuberculosis and associated factors among prisoners in Western Oromia, Ethiopia: A cross-sectional study

Dibissa, K. E.; Waktole, Z. D.; Tolessa, B. E.

10.1101/869727 — microbiology — Posted on 2019-12-09

2225 Genome variation and population structure among 1,142 mosquitoes of the African malaria vector species Anopheles gambiae and Anopheles coluzzii

Clarkson, C. S.; Miles, A.; Harding, N. J.; Lucas, E. R.; Battey, C. J.; Amaya-Romero, J. E.; Cano, J.; Diabate, A.; Constant, E.; Nwakanma, D. C.; Jawara, M.; Essandoh, J.; Dinis, J.; Le Goff, G.; Robert, V.; Troco, A. D.; Costantini, C.; Rohatgi, K. R.; Elissa, N.; Coulibaly, B.; Midega, J.; Mbogo, C.; Mawejje, H. D.; Stalker, J.; Rockett, K. A.; Drury, E.; Mead, D.; Jeffreys, A. E.; Hubbart, C.; Rowlands, K.; Isaacs, A. T.; Jyothi, D.; Malangone, C.; Kamali, M.; Henrichs, C.; Simpson, V.; Ayala, D.; Besansky, N. J.; Burt, A.; Caputo, B.; della Torre, A.; Fontaine, M.; Godfray, H. C. J.; Hah

10.1101/864314 — genomics — Posted on 2019-12-09

2226 Presynaptic dysfunction in CASK-related neurodevelopmental disorders

Becker, M.; Mastropasqua, F.; Reising, J. P.; Maier, S.; Ho, M.-L.; Rabkina, I.; Li, D.; Neufeld, J.; Ballenberger, L.; Myers, L.; Moritz, V.; Kele, M.; Wincent, J.; Willfors, C.; Sitnikov, R.; Herlenius, E.; Anderlid, B.-M.; Falk, A.; Bolte, S.; Tammimies, K.

10.1101/863308 — genetics — Posted on 2019-12-09

2227 Prognostic significances of interleukin-17-producing cells and Th17 cells in malignant cancers: a meta-analysis of the literatures

Luo, Y.; Yu, T.; Yi, C.; Shi, H.

10.1101/869776 — cancer biology — Posted on 2019-12-09

2228 Long-Term In Vivo Biocompatibility of Single-Walled Carbon Nanotubes

Galassi, T. V.; Antman-Passig, M.; Yaari, Z.; Jessurun, J.; Schwartz, R. E.; Heller, D. A.

10.1101/869750 — bioengineering — Posted on 2019-12-09

2229 A closer look at the timecourse of mind wandering: pupillary responses and behavior

Pelagatti, C.; Binda, P.; Vannucci, M.

10.1101/869768 — neuroscience — Posted on 2019-12-09

2230 GIV/Girdin and Exo70 Constitute the Core of the Mammalian Polarized Exocytic Machinery

Rohena, C.; Rajapakse, N.; Lo, I.-C.; Novick, P.; Sahoo, D.; Ghosh, P.

10.1101/870071 — cell biology — Posted on 2019-12-09

2231 Dimerization of human drebrin-like protein governs its biological activity

Ghosh, A.; Enderlein, J.; Butkevich, E.

10.1101/869925 — biophysics — Posted on 2019-12-09

2232 Quantitative assessment of bovine serum albumin proteins for blocking applications

Ma, G. J.; Ferhan, A. R.; Jackman, J. A.; Cho, N.-J.

10.1101/869677 — biophysics — Posted on 2019-12-09

2233 MLL4 is required for the first embryonic collective cell migration whereas MLL3 is not required until birth

Ashokkumar, D.; Zhang, Q.; Much, C.; Bledau, A. S.; Fu, J.; Anastassiadis, K.; Stewart, A. F.; Kranz, A.

10.1101/870329 — developmental biology — Posted on 2019-12-09

2234 Glucose metabolism promotes neonatal heart regeneration

Fajardo Martinez, V. M.; Feng, I.; Chen, B. Y.; Perez, C. A.; Shi, B.; Clark, P.; Tian, R.; Lien, C.-L.; Pellegrini, M. M.; Christofk, H.; Nakano, H.; Nakano, A.

10.1101/865790 — developmental biology — Posted on 2019-12-09

2235 Thrombospondin-1 Promotes Circuit-Specific Synapse Formation via β1-Integrin

Koh, S.; Roy, S.; Eroglu, O.; Strader, S.; Chen, W. J.; Kay, J. N.; Field, G. D.; Eroglu, C.

10.1101/866590 — neuroscience — Posted on 2019-12-09

2236 Light-induced polyp retraction and tissue rupture in the photosensitive, reef-building coral Acropora muricata

Laissue, P. P.; Gu, Y.; Qian, C.; Smith, D. J.

10.1101/862045 — developmental biology — Posted on 2019-12-09

2237 Rif1 functions in a tissue-specific manner to control replication timing through its PP1-binding motif

Armstrong, R. L.; Das, S.; Hill, C. A.; Duronio, R. J.; Nordman, J. T.

10.1101/870451 — developmental biology — Posted on 2019-12-09

2238 Keystone genes of mammalian tooth patterning and quantification of their expression

Hallikas, O.; Das Roy, R.; Christensen, M.; Renvoise, E.; Sulic, A.-M.; Jernvall, J.

10.1101/869065 — developmental biology — Posted on 2019-12-09

2239 Crystal structure of the membrane anchoring domain of mycobacterial Wag31: a dimer-of-dimer suggests how a Wag31 filament might self-assemble

Choukate, K.; Chaudhuri, B.

10.1101/869594 — biophysics — Posted on 2019-12-09

2240 Distinct architecture and composition of mouse axonemal radial spoke head revealed by cryo-EM

Zheng, W.; Li, F.; Ding, Z.; Liu, H.; Zhu, L.; Li, J.; Gao, Q.; Fu, Z.; Peng, C.; Yan, X.; Zhu, X.; Cong, Y.

10.1101/867192 — cell biology — Posted on 2019-12-09

2241 PGR5 is required for efficient Q cycle in the cytochrome b6f complex during cyclic electron flow

Buchert, F.; Mosebach, L.; Gaebelein, P.; Hippler, M.

10.1101/854489 — plant biology — Posted on 2019-12-09

2242 Fluctuating light experiments and semi-automated plant phenotyping enabled by self-built growth racks and simple upgrades to the IMAGING-PAM

Schneider, D.; Lopez, L. S.; Li, M.; Crawford, J. D.; Kirchhoff, H.; Kunz, H.-H.

10.1101/795476 — plant biology — Posted on 2019-12-09

2243 TrpML-mediated astrocyte microdomain Ca2+ transients regulate astrocyte-tracheal interactions in CNS

Ma, Z.; Freeman, M. R.

10.1101/865659 — neuroscience — Posted on 2019-12-09

2244 Visual Cell Sorting: A High-throughput, Microscope-based Method to Dissect Cellular Heterogeneity

Hasle, N.; Cooke, A.; Srivatsan, S.; Huang, H.; Stephany, J. J.; Krieger, Z.; Jackson, D. L.; Tang, W.; Monnat, R. J.; Trapnell, C.; Hatch, E. M.; Fowler, D.

10.1101/856476 — molecular biology — Posted on 2019-12-09

2245 Multiplexed single-cell transcriptomic analysis of normal and impaired lung development in the mouse

Hurskainen, M. K.; Mizikova, I.; Cook, D. P.; Cyr-Depauw, C.; Lesage, F.; Andersson, N.; Helle, E.; Renesme, L.; Jankov, R. P.; Heikinheimo, M.; Vanderhyden, B.; Thebaud, B.

10.1101/868802 — cell biology — Posted on 2019-12-09

2246 Human revealed stochastic preferences for multi-component economic choice options

Volkmann, K.; Pastor-Bernier, A.; Stasiak, A.; Grabenhorst, F.; Schultz, W.

10.1101/832881 — neuroscience — Posted on 2019-12-09

2247 Morphine differentially alters the synaptic and intrinsic properties of D1R- and D2R-expressing medium spiny neurons in the nucleus accumbens

McDevitt, D. S.; Jonik, B.; Graziane, N. M.

10.1101/858100 — neuroscience — Posted on 2019-12-09

2248 Probing the polarity of spontaneous perisomatic GABAergic synaptic transmission during epileptogenesis in the CA3 circuit in vivo

Dubanet, O.; Ferreira, A.; Frick, A.; Hirase, H.; Beyeler, A.; Leinekugel, X.

10.1101/630608 — neuroscience — Posted on 2019-12-09

2249 Methylenetetrahydrofolate reductase deficiency alters cellular response after ischemic stroke in male mice

Abato, J. E.; Moftah, M.; Cron, G. O.; Smith, P. D.; Jadavji, N. M.

10.1101/857938 — neuroscience — Posted on 2019-12-09

2250 Leveraging host metabolism for bisdemethoxycurcumin production in Pseudomonas putida

Incha, M. R.; Thompson, M. G.; Blake-Hedges, J. M.; Liu, Y.; Pearson, A. N.; Schmidt, M.; Gin, J.; Petzold, C. J.; Deutschbauer, A.; Keasling, J. D.

10.1101/753889 — microbiology — Posted on 2019-12-09

2251 A consensus phylogenomic approach highlights paleopolyploid and rapid radiation in the history of Ericales

Larson, D. A.; Walker, J. F.; Vargas, O. M.; Smith, S. A.

10.1101/816967 — evolutionary biology — Posted on 2019-12-09

2252 Comprehensive fitness maps of Hsp90 show widespread environmental dependence

Flynn, J. M.; Rossouw, A.; Cote-Hammarlof, P. A.; Fragata, I.; Mavor, D.; Hollins, C.; Bank, C.; Bolon, D. N. A.

10.1101/823468 — evolutionary biology — Posted on 2019-12-09

2253 Intention to learn modulates the impact of reward and punishment on sequence learning

Steel, A.; Baker, C. I.; Stagg, C. J.

10.1101/759639 — neuroscience — Posted on 2019-12-09

2254 ISG15/USP18/STAT2 is a molecular hub regulating autocrine IFN I-mediated control of Dengue and Zika virus replication

10.1101/784678 — immunology — Posted on 2019-12-09

2255 Housing laboratory mice deficient for Nod2 and Atg16l1 in a natural environment uncovers genetic and environmental contributions to immune variation.

Lin, J.-D.; Devlin, J. C.; Yeung, F.; McCauley, C.; Leung, J. M.; Chen, Y.-H.; Cronkite, A.; Hansen, C.; Drake-Dunn, C.; Ruggles, K. V.; Cadwell, K.; Graham, A. L.; Loke, P.

10.1101/741470 — immunology — Posted on 2019-12-09

2256 ROOT PATTERNING AND REGENERATION ARE MEDIATED BY THE QUIESCENT CENTER AND INVOLVE BLUEJAY, JACKDAW AND SCARECROW REGULATION OF VASCULATURE FACTORS

Sanchez-Corrionero, A.; Perez-Garcia, P.; Cabrera, J.; Silva-Navas, J.; Perianez-Rodriguez, J.; Gude, I.; del Pozo, J. C.; Moreno-Risueno, M. A.

10.1101/803973 — developmental biology — Posted on 2019-12-09

2257 Recombinant human soluble thrombomodulin is associated with attenuation of sepsis-induced renal impairment by inhibition of extracellular histone release

Akatsuka, M.; Masuda, Y.; Tatsumi, H.; Yamakage, M.

10.1101/780403 — pharmacology and toxicology — Posted on 2019-12-09

2258 Altered immunity of laboratory mice in the natural environment is associated with fungal colonization

Yeung, F.; Chen, Y.-H.; Lin, J.-D.; Leung, J. M.; McCauley, C.; Devlin, J. C.; Hansen, C.; Cronkite, A.; Stephens, Z. W.; Drake-Dunn, C.; Ruggles, K. V.; Round, J. L.; Loke, P.; Graham, A. L.; Cadwell, K.

10.1101/742387 — immunology — Posted on 2019-12-09

2259 jackalope: a swift, versatile phylogenomic and high-throughput sequencing simulator

Nell, L. A.

10.1101/650747 — genomics — Posted on 2019-12-09

2260 Impact of white spotting alleles, including W20, on phenotype in the American Paint Horse

Brooks, S.; Palermo, K.; Kahn, A.; Hein, J.

10.1101/678052 — genetics — Posted on 2019-12-09

2261 Reward motivation does not modulate coding of behaviorally relevant category distinctions across the frontoparietal cortex

Shashidhara, S.; Erez, Y.

10.1101/609537 — neuroscience — Posted on 2019-12-09

2262 Multi-grip classification-based prosthesis control with two EMG-IMU sensors

Krasoulis, A.; Vijayakumar, S.; Nazarpour, K.

10.1101/579367 — bioengineering — Posted on 2019-12-09

2263 No-Go Decay mRNA cleavage in the ribosome exit-tunnel produces 5'-OH ends phosphorylated by Trl1

Navickas, A.; Chamois, S.; Saint-Fort, R.; Henri, J.; Torchet, C.; Benard, L.

10.1101/465633 — molecular biology — Posted on 2019-12-09

2264 Spectral memory: Illumination evoked plasticity

Adeyefa-Olasupo, I.-E.

10.1101/490888 — animal behavior and cognition — Posted on 2019-12-09

2265 Recurrent pregnancy loss is associated with a pro-senescent decidual response during the peri-implantation window

Lucas, E. S.; Vrljicak, P.; Muter, J.; Diniz da Costa, M. M.; Brighton, P. J.; Kong, C. S.; Lipecki, J.; Fishwick, K.; Odendaal, J.; Ewington, L. J.; Quenby, S.; Ott, S.; Brosens, J. J.

10.1101/368829 — systems biology — Posted on 2019-12-09

2266 Phasic arousal suppresses biases in mice and humans across domains of decision-making

de Gee, J. W.; Tsetsos, K.; Schwabe, L.; Urai, A. E.; McCormick, D. A.; McGinley, M. J.; Donner, T. H.

10.1101/447656 — neuroscience — Posted on 2019-12-09

2267 Development of bioactive electrospun scaffolds suitable to support skin fibroblasts and release Lucilia sericata maggot excretion/secretion

Giacaman, A. G.; Styliari, I.; Taresco, V.; Pritchard, D.; Alexander, C.; Rose, F. R.

10.1101/864892 — bioengineering — Posted on 2019-12-09

2268 SEMA3F-deficient colorectal cancer cells promote lymphangiogenesis: fatty acid metabolism replace glycolysis for energy supply during lymphatic endothelial cells proliferation in tumor hypoxia microenvironment

Xiaoyuan, F.; Min, C.; Qi, Z.

10.1101/869644 — cell biology — Posted on 2019-12-09

2269 PPARG is a tumor suppressor in basal bladder tumors offering new potential therapeutic opportunities.

Coutos-Thevenot, L.; Beji, S.; Neyret-Kahn, H.; Pippo, Q.; Fontugne, J.; Osz, J.; Krucker, C.; Dos Santos Groeneveld, C.; Dufour, F.; Kamoun, A.; Ley, M.; Chapeaublanc, E.; De Reynies, A.; Lebret, T.; Allory, Y.; Cianferani, S.; Radvanyi, F.; Rochel, N.; BERNARD-PIERROT, I.

10.1101/868190 — cancer biology — Posted on 2019-12-09

2270 A multifunctional R package for identification of tumor-specific neoantigens

Hasegawa, T.; Hayashi, S.; Shimizu, E.; Mizuno, S.; Niida, A.; Yamaguchi, R.; Miyano, S.; Nakagawa, H.; Imoto, S.

10.1101/869388 — bioinformatics — Posted on 2019-12-09

2271 SODA: Multi-locus species delimitation using quartet frequencies

Rabiee, M.; Mirarab, S.

10.1101/869396 — bioinformatics — Posted on 2019-12-09

2272 Beyond accessibility: ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation

Bentsen, M.; Goymann, P.; Schultheis, H.; Petrova, A.; Klee, K.; Fust, A.; Preussner, J.; Kuenne, C.; Braun, T.; Kim, J.; Looso, M.

10.1101/869560 — bioinformatics — Posted on 2019-12-09

2273 AdaTiSS: A Novel Data-Adaptive Robust Method forQuantifying Tissue Specificity Scores

Wang, M.; Jiang, L.; Snyder, M. P.

10.1101/869404 — bioinformatics — Posted on 2019-12-09

2274 Evolutionary analysis of bacterial Non-Homologous End Joining Repair

Sharda, M.; Badrinarayanan, A.; Seshasayee, A. S. N.

10.1101/869602 — bioinformatics — Posted on 2019-12-09

2275 Cell motion-coordinated fibrillar assembly of soluble collagen I to promote MDCK cell branching formation

Wang, J.; Guo, J.; Che, B.; Ouyang, M.; Deng, L.

10.1101/869438 — biophysics — Posted on 2019-12-09

2276 Mechanical cell competition in heterogeneous epithelial tissues

Murphy, R. J.; Buenzli, P. R.; Baker, R. E.; Simpson, M. J.

10.1101/869495 — biophysics — Posted on 2019-12-09

2277 Cryo-EM Structure of the Human Mitochondrial Translocase TIM22 Complex

Qi, L.; Wang, Q.; Guan, Z.; Wu, Y.; Cao, J.; Zhang, X.; Yan, C.; Yin, P.

10.1101/869289 — biophysics — Posted on 2019-12-09

2278 Assessing the shared variation among high-dimensional data matrices: a modified version of the Procrustean correlation coefficient

Coissac, E.; Gonindard-Melodelima, C.

10.1101/842070 — bioinformatics — Posted on 2019-12-09

2279 Spectral memory: Illumination evoked plasticity

Adeyefa-Olasupo, I.-E.

10.1101/490888 — animal behavior and cognition — Posted on 2019-12-09

2280 Disease mechanism, drug-target and biomarker prediction software: Application on prostate cancer and validation

Altay, G.; Nurmemmedov, E.; Kesari, S.; Neal, D. E.

10.1101/129742 — bioinformatics — Posted on 2019-12-09

2281 FUNCTIONAL NETWORK CONNECTIVITY (FNC)-BASED GENERATIVE ADVERSARIAL NETWORK (GAN) AND ITS APPLICATIONS IN CLASSIFICATION OF MENTAL DISORDERS

Zhao, J.; Zhi, D.; Yan, W.; Calhoun, V. D.; Sui, J.

10.1101/867168 — bioengineering — Posted on 2019-12-09

2282 A revised mechanism of action of hyperaldosteronism-linked mutations in cytosolic domains of GIRK4 (KCNJ5).

Shalomov, B.; Handklo-Jamal, R.; Reddy, H. P.; Theodor, N.; Bera, A. K.; Dascal, N.

10.1101/866202 — physiology — Posted on 2019-12-09

2283 Why some size illusions affect grip aperture

Smeets, J.; Kleijn, E.; van der Meijden, M.; Brenner, E.

10.1101/866640 — neuroscience — Posted on 2019-12-09

2284 Combined use of metagenomic sequencing and host response profiling for the diagnosis of suspected sepsis.

Cheng, H. K.; Tan, S. K.; Sweeney, T. E.; Jeganathan, P.; Briese, T.; Khadka, V.; Strouts, F.; Thair, S.; Dalai, S.; Hitchcock, M.; Multani, A.; Aronson, J.; Andermann, T.; Yu, A.; Yang, S.; Holmes, S. P.; Lipkin, W. I.; Khatri, P.; Relman, D. A.

10.1101/854182 — microbiology — Posted on 2019-12-09

2285 Single-cell genomics of uncultured bacteria reveals dietary fiber responders in the mouse gut microbiota

Chijiiwa, R.; Hosokawa, M.; Kogawa, M.; Nishikawa, Y.; Ide, K.; Sakanashi, C.; Takahashi, K.; Takeyama, H.

10.1101/784801 — microbiology — Posted on 2019-12-09

2286 Exome-wide assessment of the functional impact and pathogenicity of multi-nucleotide mutations

Kaplanis, J.; Akawi, N.; Gallone, G.; McRae, J. F.; Prigmore, E.; Wright, C. F.; Fitzpatrick, D. R.; Firth, H. V.; Barrett, J. C.; Hurles, M. E.; on behalf of the Deciphering Developmental Disorders Study,

10.1101/258723 — genomics — Posted on 2019-12-09

2287 Modulatory effects of dynamic fMRI-based neurofeedback on emotion regulation networks in adolescent females

Zich, C.; Johnstone, N.; Luehrs, M.; Lisk, S.; Haller, S. P. W.; Lipp, A.; Lau, J. Y. F.; Cohen Kadosh, K.

10.1101/347971 — neuroscience — Posted on 2019-12-09

2288 A solution to the learning dilemma for recurrent networks of spiking neurons

Bellec, G.; Scherr, F.; Subramoney, A.; Hajek, E.; Salaj, D.; Legenstein, R.; Maass, W.

10.1101/738385 — neuroscience — Posted on 2019-12-09

2289 Co-ordinated regulation of cell survival and cell cycle pathways by DDR2-dependent SRF transcription factor in cardiac fibroblasts

Titus, A. S.; V, H.; Kailasam, S.

10.1101/857037 — molecular biology — Posted on 2019-12-09

2290 Seascape genomics as a new tool to empower coral reef conservation strategies: an example on north-western Pacific Acropora digitifera.

Selmoni, O.; Rochat, E.; Lecellier, G.; Veronique, B.-L.; Joost, S.

10.1101/588228 — evolutionary biology — Posted on 2019-12-09

2291 Systematics and geographical distribution of Galba species, a group of cryptic and worldwide freshwater snails

Alda, P.; Lounnas, M.; Vazquez, A. A.; Ayaqui, R.; Calvopina, M.; Celi-Erazo, M.; Dillon, R.; Gonzalez Ramirez, L. C.; Loker, E. S.; Muzzio-Aroca, J.; Narvaez, A. O.; Noya, O.; Pereira, A. E.; Robles, L. M.; Rodriguez-Hidalgo, R.; Uribe, N.; David, P.; Jarne, P.; Pointier, J.-P.; Hurtrez-Bousses, S.

10.1101/647867 — evolutionary biology — Posted on 2019-12-09

2292 Mitotic spindle disassembly in human cells relies on CRIPT-bearing hierarchical redox signals

Cai, C.; Li, H.

10.1101/869123 — cell biology — Posted on 2019-12-08

2293 Multiplexed single-cell transcriptomic analysis of normal and impaired lung development in the mouse

Hurskainen, M. K.; Mizikova, I.; Cook, D. P.; Cyr-Depauw, C.; Lesage, F.; Andersson, N.; Helle, E.; Renesme, L.; Jankov, R. P.; Heikinheimo, M.; Vanderhyden, B.; Thebaud, B.

10.1101/868802 — cell biology — Posted on 2019-12-08

2294 Faecal DNA to the rescue: Shotgun sequencing of non-invasive samples reveals two subspecies of Southeast Asian primates to be Critically Endangered species

Ang, A.; Roesma, D. I.; Nijman, V.; Meier, R.; Srivathsan, A.; Rizaldi,

10.1101/867986 — zoology — Posted on 2019-12-08

2295 A head-fixation system for continuous monitoring of force generated during behavior

Hughes, R.; Bakhurin, K.; Barter, J.; Zhang, J.; Yin, H.

10.1101/868703 — neuroscience — Posted on 2019-12-08

2296 The gap junction blocker mefloquine impairs sleep-dependent declarative memory consolidation in humans

Feld, G. B.; Ngo, H.-V.; Duran, E.; Gebhardt, S.; Kleist, L.; Brugger, K.; Fritsche, A.; Born, J.; Hallschmid, M.

10.1101/868901 — neuroscience — Posted on 2019-12-08

2297 A Method for Harmonizing Longitudinal Multi-scanner Imaging Data

Beer, J. C.; Tustison, N. J.; Cook, P. A.; Sheline, Y. I.; Shinohara, R. T.; Linn, K. A.

10.1101/868810 — neuroscience — Posted on 2019-12-08

2298 Brain computation by assemblies of neurons

Vempala, S.; Papadimitriou, C.; Mitropolsky, D.; Collins, M.; Maass, W.

10.1101/869156 — neuroscience — Posted on 2019-12-08

2299 Riboflow: using deep learning to classify riboswitches with ~99% accuracy

Premkumar, K. A. R.; Bharanikumar, R.; Palaniappan, A.

10.1101/868695 — bioinformatics — Posted on 2019-12-08

2300 A mutant of the phototoxic protein KillerRed that does not form DsRed-like chromophore

Gorbachev, D. A.; Sarkisyan, K. S.

10.1101/868877 — bioengineering — Posted on 2019-12-08

2301 Vibrio cholerae Type VI Secretion System Auxiliary Cluster 3 is a Pandemic-associated Mobile Genetic Element

Santoriello, F. J.; Michel, L.; Unterweger, D.; Pukatzki, S.

10.1101/868539 — microbiology — Posted on 2019-12-08

2302 ACE: A Probabilistic Model for Characterizing Gene-Level Essentiality in CRISPR Screens

Hutton, E.; Siepel, A.

10.1101/868919 — bioinformatics — Posted on 2019-12-08

2303 Using nonthermal plasma treatment to improve quality and durability of hydrophilic coatings on hydrophobic polymer surfaces

Learn, G. D.; Lai, E. J.; von Recum, H. A.

10.1101/868885 — bioengineering — Posted on 2019-12-08

2304 Gliotoxin, a known virulence factor in the major human pathogen Aspergillus fumigatus, is also biosynthesized by the non-pathogenic relative A. fischeri

Knowles, S. L.; Mead, M. E.; Pereira Silva, L.; Raja, H. A.; Steenwyk, J. L.; Goldman, G. H.; Rokas, A.; Oberlies, N. H.

10.1101/868745 — microbiology — Posted on 2019-12-08

2305 A naturally segregating polymorphism balancing semelparous reproduction versus reproductive diapause revealed via microfluidic assessment of starvation stress in Caenorhabditis elegans.

Archer, H.; Banse, S.; Blue, B.; Phillips, P. C.

10.1101/863878 — evolutionary biology — Posted on 2019-12-08

2306 Antibody Bank: the Synthetic Cell Repertoire for Immunotherapy

Fu, W.; Wang, C.; Ling, Y.; Ding, M.; Lei, C.; Hu, S.

10.1101/868653 — bioengineering — Posted on 2019-12-08

2307 Can we assume the gene expression profile as a proxy for signaling network activity?

Piran, M.; Karbalaee, R.; Piran, M.; Aldahdooh, J.; Mirzaie, M.; Ansari-Pour, N.; Tang, J.; Jafari, M.

10.1101/643866 — systems biology — Posted on 2019-12-08

2308 Neural correlates of response inhibition and performance monitoring in binge watching

Kilian, K.; Broeckel, K. L.; Overmeyer, R.; Dieterich, R.; Endrass, T.

10.1101/868984 — neuroscience — Posted on 2019-12-08

2309 Pervasive lesion segregation shapes cancer genome evolution

Aitken, S. J.; Anderson, C. J.; Connor, F.; Pich, O.; Sundaram, V.; Feig, C.; Rayner, T. F.; Lukk, M.; Aitken, S.; Luft, J.; Kentepozidou, E.; Arnedo-Pac, C.; Beentjes, S.; Davies, S. E.; Drews, R. M.; Ewing, A.; Kaiser, V. B.; Khamseh, A.; Lopez-Arribillaga, E.; Redmond, A. M.; Santoyo-Lopez, J.; Sentis, I.; Talmane, L.; Yates, A. D.; Semple, C. A.; Lopez-Bigas, N.; Flicek, P.; Odom, D. T.; Taylor, M. S.

10.1101/868679 — cancer biology — Posted on 2019-12-08

2310 Capturing Protein-Ligand Recognition Pathways in Coarse-grained Simulation

Dandekar, B. R.; Mondal, J.

10.1101/868687 — biophysics — Posted on 2019-12-08

2311 The α-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure

Boyer, D. R.; Li, B.; Sun, C.; Fan, W.; Zhou, K.; Hughes, M. P.; Sawaya, M. R.; Jiang, L.; Eisenberg, D. S.

10.1101/868869 — biochemistry — Posted on 2019-12-08

2312 Overstaying in patchy foraging can be explained by behavioral variability

Cash-Padgett, T. D.; Hayden, B. Y.

10.1101/868596 — animal behavior and cognition — Posted on 2019-12-08

2313 Toxicity, transfer and depuration of anatoxin-a (cyanobacterial neurotoxin) in medaka fish exposed by single-dose gavage

Marie, B.; Colas, S.; Duval, C.

10.1101/868737 — pharmacology and toxicology — Posted on 2019-12-08

2314 Prostate Specific Membrane Antigen expression in the vasculature of primary lung carcinomas associates with faster metastatic dissemination to brain

Tanjore Ramanathan, J.; Lehtipuro, S.; Sihto, H.; Tovari, J.; Reiniger, L.; Teglasi, V.; Moldvay, J.; Nykter, M.; Haapasalo, H.; Le Joncour, V.; Laakkonen, P.

10.1101/863456 — pathology — Posted on 2019-12-08

Huang, H.; Lennikov, A.

10.1101/868851 — pathology — Posted on 2019-12-08

2316 Circuit-specific dendritic development in the piriform cortex

Moreno-Velasquez, L.; Kaehne, M.; Lo, H.; Lenzi, S.; Breustedt, J.; Schmitz, D.; Rüdiger, S.; Johenning, F.

10.1101/868075 — neuroscience — Posted on 2019-12-08

Schreiber, S.

10.1101/869073 — ecology — Posted on 2019-12-08

2318 Alignment and quantification of ChIP-exo crosslinking patterns reveal the spatial organization of protein-DNA complexes

Yamada, N.; Rossi, M. J.; Farrell, N.; Pugh, B. F.; Mahony, S.

10.1101/868604 — bioinformatics — Posted on 2019-12-08

2319 Integrated biophysical characterization of fibrillar collagen-based hydrogels

Avendano, A.; Chang, J. C.; Cortes-Medina, M. G.; Seibel, A. J.; Admasu, B. R.; Boutelle, C. M.; Bushman, A. R.; Garg, A. A.; DeShetler, C. M.; Cole, S. L.; Song, J. W.

10.1101/868059 — bioengineering — Posted on 2019-12-08

2320 RatHat: A self-targeting printable brain implant system

Allen, L. M.; Jayachandran, M.; Viena, T. D.; Su, M.; Allen, T. A.

10.1101/868422 — neuroscience — Posted on 2019-12-08

2321 Multiplexed single-cell profiling of post-perturbation transcriptional responses to define cancer vulnerabilities and therapeutic mechanism of action

McFarland, J. M.; Paolella, B. R.; Warren, A.; Geiger-Schuller, K.; Shibue, T.; Rothberg, M.; Kuksenko, O.; Jones, A.; Chambers, E.; Dionne, D.; Bender, S.; Wolpin, B. M.; Ghandi, M.; Tirosh, I.; Rozenblatt-Rosen, O.; Roth, J. A.; Golub, T. R.; Regev, A.; Aguirre, A. J.; Vazquez, F.; Tsherniak, A.

10.1101/868752 — cancer biology — Posted on 2019-12-08

2322 Quantitative Structure-Mutation-Activity Relationship Tests (QSMART) Model for Protein Kinase Inhibitor Response Prediction

Huang, L.-C.; Yeung, W.; Wang, Y.; Cheng, H.; Venkat, A.; Li, S.; Ma, P.; Rasheed, K.; Kannan, N.

10.1101/868067 — bioinformatics — Posted on 2019-12-08

2323 Functional angiogenesis requires microenvironmental cues balancing endothelial cell migration and proliferation

Wang, W. Y.; Lin, D.; Jarman, E. H.; Polacheck, W. J.; Baker, B. M.

10.1101/868497 — bioengineering — Posted on 2019-12-08

2324 Chromosomal-level genome assembly of the scimitar-horned oryx: insights into diversity and demography of a species extinct in the wild

Humble, E.; Dobrynin, P.; Senn, H.; Chuven, J.; Scott, A. F.; Mohr, D. W.; Dudchenko, O.; Omer, A. D.; Colaric, Z.; Lieberman Aiden, E.; Wildt, D.; Oliagi, S.; Tamazian, G.; Pukazhenthi, B.; Ogden, R.; Koepfli, K.-P.

10.1101/867341 — genomics — Posted on 2019-12-08

2325 Evaluating the consequences of common assumptions in run reconstructions on Pacific-salmon biological status assessments

Peacock, S. J.; Hertz, E.; Holt, C. A.; Connors, B.; Freshwater, C.; Connors, K.

10.1101/868927 — ecology — Posted on 2019-12-08

2326 Administration of defective virus inhibits dengue transmission into mosquitoes

Mapder, T.; Aaskov, J.; Burrage, K.

10.1101/837849 — systems biology — Posted on 2019-12-08

2327 Factors Affecting Detection Of GMO Traces In Food And Crop Samples

Hassan, W.; Jamil, N.; Siddiqui, S.; Ali, A.; Quadri, O.; Wajeeh, M.; Khan, A. A.; Khan, S.

10.1101/869032 — plant biology — Posted on 2019-12-08

2328 Reverse-Engineering the Cortical Architecture for Controlled Semantic Cognition

Jackson, R. L.; Rogers, T. T.; Lambon Ralph, M. A.

10.1101/860528 — neuroscience — Posted on 2019-12-08

2329 The hippocampus as a perceptual map: neuronal and behavioral discrimination during memory encoding

Allegra, M.; Posani, L.; Schmidt-Hieber, C.

10.1101/868794 — neuroscience — Posted on 2019-12-08

2330 Asymptotic limits of sensorimotor adaptation

Albert, S. T.; Jang, J.; Sheahan, H. R.; Teunissen, L.; Vandevoorde, K.; Shadmehr, R.

10.1101/868406 — neuroscience — Posted on 2019-12-08

2331 Unsupervised Clustering Reveals Spatially Varying Single Neuronal Firing Patterns in the Subthalamic Nucleus of Patients with Parkinson's Disease

Kaku, H.; Ozturk, M.; Viswanathan, A.; Jimenez-Shahed, J.; Sheth, S. A.; Kumar, S.; Ince, N. F.

10.1101/863464 — neuroscience — Posted on 2019-12-08

2332 TrpML-mediated astrocyte microdomain Ca2+ transients regulate astrocyte-tracheal interactions in CNS

Ma, Z.; Freeman, M. R.

10.1101/865659 — neuroscience — Posted on 2019-12-08

2333 Single cell transcriptomic analysis revealed long-lasting adverse effects of prenatal tamoxifen administration on neurogenesis in prenatal and adult brains

Lee, C.-M.; Zhou, L.-Q.; Liu, J.-P.; Shi, J.-Y.; Geng, Y.-N.; Wang, J.-R.; Su, X.-J.; Barad, N.; Wang, J.-B.; Sun, Y.; Lin, Q.

10.1101/811893 — neuroscience — Posted on 2019-12-08

2334 TDM: a temporal decomposition method for removing venous effects from task-based fMRI

Kay, K. N.; Jamison, K. W.; Zhang, R.; Ugurbil, K.

10.1101/868455 — neuroscience — Posted on 2019-12-08

2335 Elucidation of the determinant for orchestration of solo unisexual cycle in an important human fungal pathogen

Hu, P.; Liu, H.; Chen, L.; He, G.-J.; Tian, X.; Yao, X.; Zhao, T.; Li, C.; Tao, C.; Yang, E.; Wang, L.

10.1101/867408 — microbiology — Posted on 2019-12-08

2336 The AAA+ ATPase ClpX Is Critical for Growth and Development of Chlamydia trachomatis

Wood, N. A.; Blocker, A.; seleem, m. a.; Conda-Sheridan, M.; Fisher, D. J.; Ouellette, S. P.

10.1101/868620 — microbiology — Posted on 2019-12-08

2337 Unraveling a tangled skein: Evolutionary analysis of the bacterial gibberellin biosynthetic operon

Nett, R. S.; Nguyen, N. N.; Nagel, R.; Marcassa, A.; Charles, T. C.; Friedberg, I.; Peters, R. J.

10.1101/868042 — microbiology — Posted on 2019-12-08

2338 Reprogramming of the apoplast metabolome of Lolium perenne upon infection with the mutualistic symbiont Epichloë festucae

Green, K. A.; Berry, D.; Feussner, K.; Eaton, C. J.; Ram, A.; Mesarich, C. H.; Solomon, P. H.; Feussner, I.; Scott, B.

10.1101/861450 — microbiology — Posted on 2019-12-08

2339 Neo-sex chromosomes, genetic diversity and demographic history in the Critically Endangered Raso lark

Dierickx, E. G.; Sin, S. Y. W.; van Veelen, P.; Brooke, M. d. L.; Liu, Y.; Edwards, S. V.; Martin, S. H.

10.1101/617563 — genomics — Posted on 2019-12-08

2340 Co-evolving wing spots and mating displays are genetically separable traits in Drosophila

Massey, J. H.; Rice, G. R.; Firdaus, A.; Chen, C.-Y.; Yeh, S.-D.; Stern, D.; Wittkopp, P.

10.1101/869016 — evolutionary biology — Posted on 2019-12-08

2341 Worldwide recombination in emergent white-nose syndrome pathogen Pseudogymnoascus destructans

Sharma, L.; Sousa, M.; Faria, A. S.; Nunes-Pereira, M.; Cabral, J. A.; Phillips, A. J. L.; Marques, G.; Paiva-Cardoso, M. d. N.

10.1101/868331 — ecology — Posted on 2019-12-08

2342 Ferroptotic pores induce Ca2+ fluxes and ESCRT-III activation to modulate cell death kinetics

Pedrera, L.; Espiritu, R. A.; Ros, U.; Schmitt, A.; Hailfinger, S.; Garcia-Saez, A. J.

10.1101/867564 — cell biology — Posted on 2019-12-08

2343 Machine Source Localization of Tursiops truncatus Whistle-like Sounds in a Reverberant Aquatic Environment

Woodward, S. F.; Reiss, D.; Magnasco, M.

10.1101/606673 — biophysics — Posted on 2019-12-08

2344 Compact attractors of an antithetic integral feedback system have a simple structure

Margaliot, M.; Sontag, E. D.

10.1101/868000 — bioengineering — Posted on 2019-12-08

2345 Cognitive Functions Mediate the Effect of Preterm Birth on Mathematics Skills in Young Children

Adrian, J. A.; Bakeman, R.; Akshoomoff, N.; Haist, F.

10.1101/868547 — developmental biology — Posted on 2019-12-08

2346 kRISP-meR: A Reference-free Guide-RNA Design Tool for CRISPR/Cas9

Hera, M. R.; Rahman, A.; Rahman, A.

10.1101/869115 — bioinformatics — Posted on 2019-12-08

2347 Characterizing neuroanatomic heterogeneity in people with and without ADHD based on subcortical brain volumes

Li, T.; Rooij, D. v.; Mota, N. R.; Buitelaar, J. K.; the ENIGMA ADHD Working Group, ; Hoogman, M.; Vasquez, A. A.; Franke, B.

10.1101/868414 — neuroscience — Posted on 2019-12-08

2348 Sex-based mutational landscape confers sensitivity to checkpoint blockade immunotherapy in cutaneous melanoma

Jia, M.; Chi, T.

10.1101/868950 — immunology — Posted on 2019-12-08

2349 The effects of arbuscular mycorrhizal fungi (AMF) and Rhizophagus irregularis in soil microorganisms accessed by metatranscriptomics and metaproteomics

Lammel, D.; Meierhofer, D.; Johnston, P. R.; Mbedi, S.; Rillig, M. C.

10.1101/860932 — ecology — Posted on 2019-12-08

2350 Mitf-family transcription factor function is required within cranial neural crest cells to promote choroid fissure closure

Sinagoga, K.; Larimer-Picciani, A.; George, S.; Spencer, S.; Lister, J.; Gross, J.

10.1101/869040 — developmental biology — Posted on 2019-12-08

2351 The dynamic transmission of positional information in stau- mutants during Drosophila embryogenesis

Yang, Z.; Zhu, H.; Kong, K.; Chen, J.; Wu, X.; Li, P.; Jiang, J.; Zhao, J.; Liu, F.

10.1101/868711 — developmental biology — Posted on 2019-12-08

2352 Energy Crisis in Human and Mouse Models of SLC4A11-associated Corneal Endothelial Dystrophies

Zhang, W.; Frausto, R.; Chung, D.; Griffis, C. G.; Kao, L.; Chen, A.; Azimov, R.; Sampath, A.; Kurtz, I.; Aldave, A.

10.1101/868281 — cell biology — Posted on 2019-12-08

2353 Neutrophil extracellular trap formation correlates with improved overall survival in ovarian cancer

Muqaku, B.; Pils, D.; Mader, J. C.; Aust, S.; Mangold, A.; Muqaku, L.; Slany, A.; Del Favero, G.; Gerner, C.

10.1101/862292 — cancer biology — Posted on 2019-12-08

2354 A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery

Ripstein, Z. A.; Vahidi, S.; Houry, W. A.; Rubinstein, J. L.; Kay, L. E.

10.1101/780494 — biophysics — Posted on 2019-12-08

2355 Integration of action value during action observation

Cretu, A. L.; Lehner, R.; Polania, R.; Wenderoth, N.

10.1101/868083 — neuroscience — Posted on 2019-12-08

2356 Citrusgreening.org: An open access and integrated systems biology portal for the Huanglongbing (HLB) disease complex

Flores-Gonzalez, M.; Hosmani, P. S.; Fernandez-Pozo, N.; Mann, M.; Humann, J. L.; Main, D.; Heck, M.; Brown, S. J.; Mueller, L. A.; Saha, S.

10.1101/868364 — bioinformatics — Posted on 2019-12-08

2357 The connectome of the Caenorhabditis elegans pharynx

Cook, S. J.; Crouse, C. M.; Yemini, E.; Hall, D. H.; Emmons, S. W.; Hobert, O.

10.1101/868513 — neuroscience — Posted on 2019-12-08

2358 Akt1-associated actomyosin remodelling is required for nuclear lamina dispersal and nuclear shrinkage in epidermal terminal differentiation

Rogerson, C.; Wotherspoon, D. J.; O'Shaughnessy, R. F. L.

10.1101/868034 — cell biology — Posted on 2019-12-08

2359 Excitation of Faraday-like body waves in vibrated living earthworms

Maksymov, I.; Pototsky, A.

10.1101/868521 — biophysics — Posted on 2019-12-08

2360 Chances and challenges of machine learning based disease classification in genetic association studies illustrated on age-related macular degeneration

Guenther, F.; Brandl, C.; Winkler, T. W.; Wanner, V.; Stark, K.; Kuechenhoff, H.; Heid, I. M.

10.1101/867697 — genetics — Posted on 2019-12-08

2361 The tuatara genome: insights into vertebrate evolutionfrom the sole survivor of an ancient reptilian order

Gemmell, N.; Rutherford, K.; Prost, S.; Tollis, M.; Winter, D. J.; Macey, J. R.; Adelson, D. L.; Suh, A.; Bertozzi, T.; Grau, J.; Organ, C.; Gardner, P.; Muffato, M.; Patricio, M.; Billis, K.; Martin, F. J.; Flicek, P.; Petersen, B.; Kang, L.; Michalak, P.; Buckley, T.; Wilson, M. A.; Cheng, Y.; Miller, H.; Schott, R. K.; Jordan, M.; Newcomb, R.; Arroyo, J. I.; Valenzuela, N.; Hore, T. A.; Renart, J.; Peona, V.; Peart, C.; Warmuth, V.; ZENG, L.; Kortschak, D.; Raison, J. M.; Zapata, V. V.; Wu, Z.; Santesmasses, D.; Mariotti, M.; Guigo, R.; Rupp, S.; Twort, V.; Dussex, N.; Taylor, H. R.; Abe, H

10.1101/867069 — genomics — Posted on 2019-12-08

2362 Genetic profiling of 2,683 Vietnamese genomes from non-invasive prenatal testing data

Tran, N. H.; Vo, T. B.; Nguyen, V. T.; Tran, N. T.; Trinh, T.-H. N.; Pham, H.-A. T.; Dao, H. T.; Nguyen, N. M.; Van, Y.-L. T.; Tran, V. U.; Vu, H. G.; Bui, Q.-T. N.; Vo, P.-A. N.; Nguyen, H. N.; Nguyen, Q.-T. T.; Do, T.-T. T.; Cao Thi Ngoc, P.; Truong, D. K.; Nguyen, H.-N.; Giang, H.; Phan, M.-D.

10.1101/868588 — genomics — Posted on 2019-12-08

2363 Large scale genome-wide association study reveals that drought induced lodging in grain sorghum is associated with plant height and traits linked to carbon remobilisation

Wang, X.; Mace, E. S.; Tao, Y.; Cruickshank, A.; Hunt, C.; Hammer, G. L.; Jordan, D. R.

10.1101/865667 — genetics — Posted on 2019-12-08

2364 Phase-amplitude markers of synchrony and noise: A resting-state and TMS-EEG study of schizophrenia

Freche, D.; Naim-Feil, J.; Hess, S.; Peled, A.; Grinshpoon, A.; Moses, E.; Levit-Binnun, N.

10.1101/740621 — neuroscience — Posted on 2019-12-08

2365 Evaluating Representations for Gene Ontology Terms

Duong, D.; Uppunda, A.; Ju, C. J.-T.; Zhang, J.; Chen, M.; Eskin, E.; Li, J. J.; Chang, K.-W.

10.1101/765644 — bioinformatics — Posted on 2019-12-08

2366 Extracellular adenosine enhances the ability of PMNs to kill Streptococcus pneumoniae by inhibiting IL-10 production

Siwapornchai, N.; Lee, J. N.; Tchalla, E. Y. I.; Bhalla, M.; Hui Yeoh, J.; Roggensack, S. E.; Leong, J. M.; Bou Ghanem, E. N.

10.1101/716456 — immunology — Posted on 2019-12-08

2367 New interpretable machine learning method for single-cell data reveals correlates of clinical response to cancer immunotherapy

Greene, E.; Finak, G.; D'Amico, L. A.; Bhardwaj, N.; Church, C. D.; Morishima, C.; Ramchurren, N.; Taube, J. M.; Nghiem, P. T.; Cheever, M. A.; Fling, S. P.; Gottardo, R.

10.1101/702118 — bioinformatics — Posted on 2019-12-08

2368 The Relationship Between Genome Size and Metabolic Rate in Extant Vertebrates

Gardner, J. D.; Laurin, M.; Organ, C. L.

10.1101/659094 — evolutionary biology — Posted on 2019-12-08

2369 Molecular insights from conformational ensembles via Machine Learning

Fleetwood, O.; Kasimova, M. A.; Westerlund, A.; Delemotte, L.

10.1101/695254 — biophysics — Posted on 2019-12-08

2370 M3C: A Monte Carlo reference-based consensus clustering algorithm

John, C. R.; Watson, D.; Russ, D.; Goldmann, K.; Ehrenstein, M.; Lewis, M.; Pitzalis, C.; Barnes, M.

10.1101/377002 — bioinformatics — Posted on 2019-12-08

2371 Disease mechanism, drug-target and biomarker prediction software: Application on prostate cancer and validation

Altay, G.; Nurmemmedov, E.; Kesari, S.; Neal, D. E.

10.1101/129742 — bioinformatics — Posted on 2019-12-08

2372 Subcellular localization of glypican-5 associates with dynamic cell motility and cell communication of the human mesenchymal stem cell line U3DT

Takeuchi, M.; Takeuchi, K.; Monobe, Y.; Takai, T.; Yamaguchi, R.; Takeuchi, J. K.; Akagi, K.-i.

10.1101/863720 — cell biology — Posted on 2019-12-07

2373 A Deep Learning approach predicts the impact of point mutations in intronic flanking regions on micro-exon splicing definition

daSilva, L. F.; Tahira, A. C.; Mesel, V.; Verjovski-Almeida, S.

10.1101/868786 — bioinformatics — Posted on 2019-12-07

2374 Differential gene expression elicited by ZIKV infection in trophoblasts from congenital Zika syndrome discordant twins

Amaral, M. S.; Goulart, E.; Caires-Junior, L. C.; Morales-Vicente, D. A.; Soares-Schanoski, A.; Gomes, R. P.; Olberg, G. G. O.; Astray, R. M.; Kalil, J. E.; Zatz, M.; Verjovski-Almeida, S.

10.1101/867465 — microbiology — Posted on 2019-12-07

2375 A nanobody-based fluorescent reporter reveals human α-synuclein in the cell cytosol

Gerdes, C.; Waal, N.; Offner, T.; Fornasiero, E. F.; Wender, N.; Verbarg, H.; Manzini, I.; Trenkwalder, C.; Mollenhauer, B.; Strohaeker, T.; Zweckstetter, M.; Becker, S.; Rizzoli, S. O.; Basmanav, B.; Opazo, F.

10.1101/846014 — neuroscience — Posted on 2019-12-07

2376 Reanalysis And Integration Of Public Microarray Datasets Reveals Novel Host Genes Modulated In Leprosy

Leal-Calvo, T.; Moraes, M. O.

10.1101/824805 — genomics — Posted on 2019-12-07

2377 Genetic and epigenetic signatures associated with the rapid radiation of Aquilegia species

Lu, T.; Li, M.-R.; Ding, N.; Wang, Z.-H.; Lan, L.-Z.; Gao, X.; Li, L.-F.

10.1101/782821 — plant biology — Posted on 2019-12-07

2378 Distinguishing coalescent models - which statistics matter most?

Freund, F.; Siri-Jegousse, A.

10.1101/679498 — evolutionary biology — Posted on 2019-12-07

2379 Niche complementarity among pollinators increases community-level plant reproductive success

Magrach, A.; Molina, F. P.; Bartomeus, I.

10.1101/629931 — ecology — Posted on 2019-12-07

2380 Translationally Controlled Tumor Protein TCTP as Peptide Vaccine against Schistosoma japonicum: an Immunoinformatics Approach

Abdalrahman, R. A.; Ahmed, S. S.; Elnaeem, M. A.; Mohammed, M. S.; Jammie, N. M.; Yousif, I. A.; Mohamed, W. H.; Nasr, S. Y.; Awad-Elkareem, M. A.; Hassan, M. A.

10.1101/466847 — bioinformatics — Posted on 2019-12-07

2381 A Study of Representational Similarity: The Emergence of Object Concepts in Rapid Serial Visual Presentation Streams

Zhou, I. X. D.; Grootswagers, T.; Segula, B.; Robinson, A.; Shatek, S.; Whyte, C.; Carlson, T.

10.1101/824565 — neuroscience — Posted on 2019-12-07

2382 Ludicrous Speed Linear Mixed Models for Genome-Wide Association Studies

Kadie, C. M.; Heckerman, D.

10.1101/154682 — bioinformatics — Posted on 2019-12-07

2383 The evolutionary origin of the universal distribution of mutation fitness effect

Barlukova, A.; Pedruzzi, G.; Rouzine, I. M.

10.1101/867390 — bioinformatics — Posted on 2019-12-07

2384 Structural analysis of nonapeptides derived from elastin

Hernandez, B.; Crowet, J.-M.; Thiery, J.; Kruglik, S. G.; Belloy, N.; Baud, S.; Dauchez, M.; Debelle, L.

10.1101/868257 — biochemistry — Posted on 2019-12-07

2385 Chromosome-scale genome assembly of a single outbred Drosophila melanogaster

Adams, M.; McBroome, J.; Maurer, N.; Pepper-Tunick, E.; Saremi, N.; Green, R. E.; Vollmers, C.; Corbett-Detig, R. B.

10.1101/866988 — genomics — Posted on 2019-12-07

2386 α1A-adrenoceptor inverse agonists and agonists modulate receptor signalling through a conformational selection mechanism

Gooley, P. R.; Wu, F.; Williams, L. M.; Abdul-Ridha, A.; Gunatilaka, A.; Vaid, T. M.; Kocan, M.; Whitehead, A. R.; Griffin, M.; Bathgate, R. A. D.; Scott, D. J.

10.1101/866475 — biochemistry — Posted on 2019-12-07

2387 Skin Lesions Classification Using Deep Learning Based on Dilated Convolution

Ratul, M. A. R.; Mozaffari, M. H.; Lee, D. W.; Parimbelli, D. E.

10.1101/860700 — cancer biology — Posted on 2019-12-07

2388 Cell-to-cell variability in JAK2/STAT5 pathway components and cytoplasmic volumes define survival threshold in erythroid progenitor cells

Adlung, L.; Stapor, P.; Toensing, C.; Schmiester, L.; Schwarzmueller, L.; Wang, D.; Timmer, J.; Klingmueller, U.; Hasenauer, J.; Schilling, M.

10.1101/866871 — systems biology — Posted on 2019-12-07

2389 Brown adipose expansion and remission of glycemic dysfunction in obese SM/J mice

Carson, C.; Macias-Velasco, J. F.; Gunawardana, S.; Miranda, M. A.; Oyama, S.; Schmidt, H.; Wayhart, J. P.; Lawson, H. A.

10.1101/724369 — physiology — Posted on 2019-12-07

2390 Data-driven classification of spectral profiles reveals brain region-specific plasticity

Lubinus, C.; Orpella, J.; Keitel, A.; Gudi-Mindermann, H.; Engel, A. K.; Roeder, B.; Rimmele, J. M.

10.1101/782979 — neuroscience — Posted on 2019-12-07

2391 Learning cognitive maps for vicarious evaluation

Rikhye, R. V.; Gothoskar, N.; Guntupalli, J. S.; Dedieu, A.; Lazaro-Gredilla, M.; George, D.

10.1101/864421 — neuroscience — Posted on 2019-12-07

2392 Bond type and discretization of non-muscle myosin II are critical for simulated contractile dynamics

Cortes, D. B.; Gordon, M. B.; Nedelec, F. J.; Maddox, A. S.

10.1101/669382 — cell biology — Posted on 2019-12-07

2393 CUB domain-containing protein 1 controls HGF responses by integrating Src and Met-STAT3 signaling

Kajiwara, K.; Sugihara, A.; Aoki, K.; Okuzaki, D.; Matsumoto, K.; Okada, M.

10.1101/789339 — cell biology — Posted on 2019-12-07

2394 Seizure pathways change on circadian and slower timescales in individual patients with focal epilepsy

Schroeder, G. M.; Diehl, B.; Chowdhury, F. A.; Duncan, J. S.; de Tisi, J.; Trevelyan, A. J.; Forsyth, R.; Jackson, A.; Taylor, P. N.; Wang, Y.

10.1101/661371 — neuroscience — Posted on 2019-12-07

2395 All of gene expression (AOE): an integrated index for public gene expression databases

Bono, H.

10.1101/626754 — bioinformatics — Posted on 2019-12-07

2396 VIP-producing enteric neurons interact with innate lymphoid cells to regulate feeding-dependent intestinal epithelial barrier functions

Talbot, J.; Hahn, P.; Kroehling, L.; Nguyen, H.; Li, D.; Littman, D. R.

10.1101/721464 — immunology — Posted on 2019-12-07

2397 Learning from Synthetic Dataset for Crop Seed Instance Segmentation

Toda, Y.; Okura, F.; Ito, J.; Okada, S.; Kinoshita, T.; Tsuji, H.; Saisho, D.

10.1101/866921 — bioinformatics — Posted on 2019-12-07

2398 Sierra: Discovery of differential transcript usage from polyA-captured single-cell RNA-seq data

Patrick, R.; Humphreys, D.; Oshlack, A.; Ho, J. W. K.; Harvey, R. P.; Lo, K. K.

10.1101/867309 — bioinformatics — Posted on 2019-12-07

2399 Maternal high-fat diet induces sex-specific changes to glucocorticoid and inflammatory signaling in response to corticosterone and lipopolysaccharide challenge in adult rat offspring

Wijenayake, S.; Rahman, M. F.; Lum, C. M.; de Vega, W. C.; Sasaki, A.; McGowan, P. O.

10.1101/780783 — neuroscience — Posted on 2019-12-07

2400 Evolution under pH stress and high population densities leads to increased density-dependent fitness in the protist Tetrahymena thermophila

Moerman, F.; Arquint, A.; Merkli, S.; Wagner, A.; Altermatt, F.; Fronhofer, E. A.

10.1101/758300 — evolutionary biology — Posted on 2019-12-07

2401 Improving the clinical performance of blood-based DNA methylation biomarkers utilizing locus-specific epigenetic heterogeneity

Miller, B. F.; Pisanic, T. R.; Margolin, G.; Petrykowska, H. M.; Athamanolap, P.; Goncearenco, A.; Osei-Tutu, A.; Annunziata, C. M.; Wang, T.-H.; Elnitski, L.

10.1101/579839 — bioinformatics — Posted on 2019-12-07

2402 Machine Source Localization of Tursiops Truncatus Whistle-like Sounds in a Reverberant Aquatic Environment

Woodward, S. F.; Reiss, D.; Magnasco, M.

10.1101/606673 — biophysics — Posted on 2019-12-07

2403 The effect of dopamine transporter blockade on optical self-stimulation: behavioral and computational evidence for parallel processing in brain reward circuitry

Trujillo-Pisanty, I.; Conover, K.; Solis, P.; Palacios, D.; Shizgal, P.

10.1101/867481 — neuroscience — Posted on 2019-12-06

2404 HBV DNA is a substrate for the cGAS/STING pathway but is not sensed in infected hepatocytes

Lauterbach-Riviere, L.; Bergez, M.; Mönch, S.; Qu, B.; Riess, M.; Vondran, F.; Liese, J.; Hornung, V.; Urban, S.; Koenig, R.

10.1101/867440 — microbiology — Posted on 2019-12-06

2405 Measles skin rash: infection of lymphoid and myeloid cells in the dermis precedes viral dissemination to keratinocytes in the epidermis

Laksono, B. M.; Fortugno, P.; Nijmeijer, B. M.; de Vries, R. D.; Cordisco, S.; van Nieuwkoop, S.; Kuiken, T.; Geijtenbeek, T. B. H.; Duprex, W. P.; Brancati, F.; de Swart, R. L.

10.1101/867531 — microbiology — Posted on 2019-12-06

2406 Structural role of essential light chains in the apicomplexan glideosome

Pazicky, S.; Dhamotharan, K.; Kaszuba, K.; Mertens, H.; Gilberger, T.; Svergun, D.; Kosinski, J.; Weininger, U.; Löw, C.

10.1101/867499 — biophysics — Posted on 2019-12-06

2407 Sequence-structure-function relationships in class I MHC: a local frustration perspective

Sercinoglu, O.; Ozbek, P.

10.1101/867473 — biophysics — Posted on 2019-12-06

2408 The socioeconomic burden of severe mental disorder in China, 2014-2017: a prevalence study

Xie, M.; Ju, K.; Ni, J.; Zhao, X.; Li, X.; Pan, J.; Zhou, Q.

10.1101/867432 — scientific communication and education — Posted on 2019-12-06

2409 Interacting roles of lateral and medial Orbitofrontal cortex in decision-making and learning : A system-level computational model

Nallapu, B. T.; ALEXANDRE, F.

10.1101/867515 — neuroscience — Posted on 2019-12-06

2410 Adaptation to transients disrupts spatial coherence in binocular rivalry

Naber, M.; Stuit, S.; De Kloe, Y.; Van der Stigchel, S.; Paffen, C. L. E.

10.1101/867374 — neuroscience — Posted on 2019-12-06

2411 Bacterial and plant produced lipids can exacerbate the Olive Quick Decline Syndrome caused by Xylella

Reverberi, M.; scala, v.; pucci, n.; salustri, m.; Vodesti, V.; l'aurora, a.; scortichini, m.; zaccaria, m.; momeni, b.; loreti, s.

10.1101/867523 — microbiology — Posted on 2019-12-06

2412 Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases

Zheng, J.; Haberland, V.; Baird, D.; Walker, V. M.; Haycock, P. M.; Hurle, M.; Gutteridge, A. X.; Erola, P.; Liu, Y.; Luo, S.; Richardson, T. M.; Staley, J.; Elsworth, B.; Burgess, S.; Sun, B. B.; Danesh, J.; Runz, H.; Maranville, J. C.; Martin, H.; Yarmolinsky, J.; Laurin, C.; Holmes, M. V.; Liu, J.; Estrada, K.; Santos, R.; McCarthy, L. C.; Waterworth, D. M.; Nelson, M. R.; Butterworth, A. S.; Davey Smith, G.; Hemani, G. V.; Scott, R. A.; Gaunt, T. R.; Robinson, J.

10.1101/627398 — genetics — Posted on 2019-12-06

2413 A spiking neural-network model of goal-directed behaviour

Basanisi, R.; Brovelli, A.; Cartoni, E.; Baldassarre, G.

10.1101/867366 — animal behavior and cognition — Posted on 2019-12-06

2414 Differential gene expression elicited by ZIKV infection in trophoblasts from congenital Zika syndrome discordant twins

Amaral, M. S.; Goulart, E.; Caires-Junior, L. C.; Morales-Vicente, D. A.; Soares-Schanoski, A.; Gomes, R. P.; Olberg, G. G. O.; Astray, R. M.; Kalil, J. E.; Zatz, M.; Verjovski-Almeida, S.

10.1101/867465 — microbiology — Posted on 2019-12-06

2415 High resolution mapping of a Hordeum bulbosum-derived powdery mildew resistance locus in barley using distinct homologous introgression lines

Hoseinzadeh, P.; Ruge-Wehling, B.; Schweizer, P.; Stein, N.; Pidon, H.

10.1101/867960 — plant biology — Posted on 2019-12-06

2416 Phagocytic glia are obligatory intermediates in transmission of mutant huntingtin aggregates across neuronal synapses

Donnelly, K. M.; DeLorenzo, O. R.; Thu, W. M.; Pisano, G. E.; Luo, L.; Kopito, R. R.; Panning Pearce, M. M.

10.1101/868448 — cell biology — Posted on 2019-12-06

2417 Mitophagy contributes to alpha-tocopheryl succinate toxicity in GSNOR-deficient hepatocellular carcinoma.

Rizza, S.; Di Leo, L.; Mandatori, S.; De Zio, D.; Filomeni, G.

10.1101/867846 — cancer biology — Posted on 2019-12-06

2418 Efficient Manipulation and Generation of Kirchhoff Polynomials for the Analysis of Non-equilibrium Biochemical Reaction Networks

Yordanov, P. S.; Stelling, J.

10.1101/868323 — bioinformatics — Posted on 2019-12-06

2419 Minimally Complex Nucleic Acid Feedback Control Systems for First Experimental Implementations

Paulino, N. M. G.; Foo, M.; de Greef, T. F. A.; Kim, J.; Bates, D. G.

10.1101/867945 — synthetic biology — Posted on 2019-12-06

2420 Co-immunoprecipitation with MYR1 identifies three additional proteins within the Toxoplasma parasitophorous vacuole required for translocation of dense granule effectors into host cells

Cygan, A. M.; Theisen, T. C.; Mendoza, A. G.; Marino, N. D.; Panas, M. W.; Boothroyd, J. C.

10.1101/867788 — microbiology — Posted on 2019-12-06

2421 Recovering individual haplotypes and a contiguous genome assembly from pooled long read sequencing of the diamondback moth (Lepidoptera: Plutellidae)

Whiteford, S.; van't Hof, A. E.; Krishna, R.; Marubbi, T.; Widdison, S.; Saccheri, I. J.; Guest, M.; Morrison, N. I.; Darby, A. C.

10.1101/867879 — genomics — Posted on 2019-12-06

2422 Mapping chromatin accessibility and active regulatory elements reveals new pathological mechanisms in human gliomas

Stepniak, K.; Machnicka, M. A.; Mieczkowski, J.; Macioszek, A.; Wojtas, B.; Gielniewski, B.; Krol, S. K.; Guzik, R.; Dabrowski, M. J.; Draminski, M.; Jardanowska, M.; Grabowicz, I.; Dziedzic, A.; Kranas, H.; Sienkiewicz, K.; Diamanti, K.; Kotulska, K.; Grajkowska, W.; Roszkowski, M.; Czernicki, T.; Marchel, A.; Komorowski, J.; Kaminska, B.; Wilczynski, B.

10.1101/867861 — cancer biology — Posted on 2019-12-06

2423 Population-specific recombination maps from segments of identity by descent

Zhou, Y.; Browning, B. L.; Browning, S.

10.1101/868091 — evolutionary biology — Posted on 2019-12-06

2424 RADAR: Differential analysis of MeRIP-seq data with a random effect model

Zhang, Z.; Zhan, Q.; Eckert, M.; Zhu, A.; Chryplewicz, A.; De Jesus, D. F.; Ren, D.; Kulkarni, R. N.; Lengyel, E.; He, C.; Chen, M.

10.1101/867903 — bioinformatics — Posted on 2019-12-06

2425 Proteome-wide structural probing of low-abundant protein interactions by crosslinking

Fuersch, J.; Kammer, K.; Kreft, S. G.; Stengel, F.; Beck, M.

10.1101/867952 — systems biology — Posted on 2019-12-06

2426 Genome-Scale Characterization of Predicted Plastid-Targeted Proteomes in Higher Plants

Christian, R.; Hewitt, S. L.; Roalson, E. H.; Dhingra, A.

10.1101/867242 — plant biology — Posted on 2019-12-06

2427 Quantifying the polygenic architecture of the human cerebral cortex: Extensive genetic overlap between cortical thickness and surface area

van der Meer, D.; Frei, O.; Kaufmann, T.; Chen, C.-H.; Thompson, W. K.; O'Connell, K. S.; Monereo Sanchez, J.; Linden, D. E.; Westlye, L. T.; Dale, A. M.; Andreassen, O. A.

10.1101/868307 — neuroscience — Posted on 2019-12-06

2428 Evolutionarily ancient BAH-PHD protein mediates Polycomb silencing

Wiles, E. T.; McNaught, K. J.; De Silva, S. M.; Kaur, G.; Selker, J. M.; Ormsby, T.; Aravind, L.; Musselman, C. A.; Selker, E. U.

10.1101/868117 — molecular biology — Posted on 2019-12-06

2429 Acetobacteraceae in the honey bee gut comprise two distant clades with diverging metabolism and ecological niches

Bonilla-Rosso, G.; Paredes, J. C.; Das, S.; Ellegaard, K. M.; Emery, O.; Garcia-Garcera, M.; Glover, N.; Hadadi, N.; van der Meer, J. R.; SAGE class 2017-18, ; Tagini, F.; Engel, P.

10.1101/861260 — genomics — Posted on 2019-12-06

2430 Genomic differentiation and intercontinental population structure of mosquito vectors Culex pipiens pipiens and Culex pipiens molestus

Yurchenko, A. A.; Masri, R. A.; Khrabrova, N. V.; Sibataev, A. K.; Fritz, M.; Sharakhova, M. V.

10.1101/867887 — genomics — Posted on 2019-12-06

2431 Metrics for conservation success: using the 'Bird-Friendliness Index' to evaluate grassland and aridland bird community resilience across the Northern Great Plains ecosystem

Michel, N. L.; Burkhalter, C.; Wilsey, C. B.; Holloran, M.; Holloran, A.; Langham, G. M.

10.1101/868356 — ecology — Posted on 2019-12-06

2432 Perinatal selective serotonin reuptake inhibitor exposure and behavioral outcomes: a systematic review and meta-analyses of animal studies

Ramsteijn, A. S.; Van de Wijer, L.; Rando, J.; van Luijk, J.; Homberg, J. R.; Olivier, J. D. A.

10.1101/868265 — animal behavior and cognition — Posted on 2019-12-06

2433 Transposable element landscape in Drosophila populations selected for longevity

Fabian, D. K.; Donertas, H. M.; Fuentealba Valenzuela, M.; Partridge, L.; Thornton, J. M.

10.1101/867838 — evolutionary biology — Posted on 2019-12-06

2434 How community adaptation affects biodiversity-ecosystem-functioning relationships

Aubree, F.; David, P.; Jarne, P.; Loreau, M.; Mouquet, N.; Calcagno, V.

10.1101/867820 — evolutionary biology — Posted on 2019-12-06

2435 Allopatric speciation is more prevalent than parapatric ecological divergence in tropical montane systems (Asteraceae: Piofontia)

Vargas, O. M.; Simpson, B. B.

10.1101/868216 — evolutionary biology — Posted on 2019-12-06

2436 Proteomics identifies signal peptide features determining the substrate specificity in human Sec62/Sec63-dependent ER protein import

Zimmermann, R.; Lang, S.; Schorr, S.; Hassdenteufel, S.; Cavalie, A.; Greiner, M.; Weissgerber, P.; Dudek, J.; Nguyen, D.; Helms, V.; Foerster, F.; Nagaraj, N.; Paton, J. C.; Paton, A. W.; Molinari, M.; Loi, M.

10.1101/867762 — biochemistry — Posted on 2019-12-06

2437 Interpreting mutational effects predictions, one substitution at a time

Sruthi, C. K.; Prakash, M. K.

10.1101/867812 — biochemistry — Posted on 2019-12-06

2438 An endoribonuclease-based incoherent feedforward loop for decoupling resource-limited genetic modules

Jones, R. D.; Qian, Y.; DiAndreth, B.; Siciliano, V.; Huh, J.; Weiss, R.; Del Vecchio, D.

10.1101/867028 — synthetic biology — Posted on 2019-12-06

2439 Comprehensive single-PCR 16S and 18S rRNA community analysis validated with mock communities and denoising algorithms

Yeh, Y.-C.; McNichol, J. C.; Needham, D. M.; Fichot, E. B.; Fuhrman, J. A.

10.1101/866731 — microbiology — Posted on 2019-12-06

2440 ZBED2 is an antagonist of Interferon Regulatory Factor 1 and modulates cell identity in pancreatic cancer

Somerville, T.; Xu, Y.; Wu, X.; Vakoc, C.

10.1101/868141 — cancer biology — Posted on 2019-12-06

2441 BAX and SMAC Regulate Bistable Properties of the Apoptotic Caspase System

McKenna, S.; Garcia-Gutierrez, L.; Matallanas, D.; Fey, D.

10.1101/867663 — systems biology — Posted on 2019-12-06

2442 Fluorescence-based whole plant imaging and phenomics

Rigoulot, S. B.; Schimel, T. M.; Lee, J.; Brabazon, H.; Meier, K. A.; Schmid, M. J.; Seaberry, E. M.; Poindexter, M. R.; Layton, J. S.; Brabazon, J. W.; Madajian, J. A.; Finander, M. J.; DiBenedetto, J.; Occhialini, A.; Lenaghan, S. C.; Stewart, C. N.

10.1101/865428 — plant biology — Posted on 2019-12-06

2443 Deviant cortical sulcation related to schizophrenia, but not cognitive deficits, likely predate brain development in the second trimester.

Mackinley, M.; Sabesan, P.; Palaniyappan, L.

10.1101/868133 — neuroscience — Posted on 2019-12-06

2444 Cocaine memory reactivation induces functional adaptations of fast-spiking interneurons in the rat medial prefrontal cortex

Jorgensen, E. T.; Gonzalez, A. E.; Harkness, J. H.; Hegarty, D. M.; Burchi, D. J.; Aadland, J. A.; Aicher, S. A.; Sorg, B. A.; Brown, T. E.

10.1101/868299 — neuroscience — Posted on 2019-12-06

2445 Independent effects of socioeconomic status and genetics on adolescent cognition and brain development.

Judd, N.; Sauce, B.; Wiedenhoeft, J.; Tromp, J.; Chaarani, B.; Schliep, A.; Stringaris, A.; van Noort, B.; Penttila, J.; Grimmer, Y.; Insensee, C.; Becker, A.; Banaschewski, T.; Bokde, A.; Quinlan, E. B.; Desrivieres, S.; Flor, H.; Grigis, A.; Gowland, P.; Ittermann, B.; Martinot, J.-L.; Martinot, M.-L.; Artiges, E.; Nees, F.; Orfanos, D.; Paus, T.; Poustka, L.; Hohmann, S.; Millenet, S.; Frohner, J.; Smolka, M.; Walter, H.; Whelan, R.; Schumann, G.; Garavan, H.; Klingberg, T.

10.1101/866624 — neuroscience — Posted on 2019-12-06

2446 A genome-wide loss-of-function screen identifies Toxoplasma gondii genes that determine fitness in interferon gamma-activated murine macrophages

Wang, Y.; Sangare, L. O.; Paredes-Santos, T. C.; Krishnamurthy, S.; Hassan, M. A.; Furuta, A. M.; Markus, B. M.; Lourido, S.; Saeij, J. P. J.

10.1101/867705 — microbiology — Posted on 2019-12-06

2447 Population genetics of the coral Acropora millepora: Towards a genomic predictor of bleaching

Fuller, Z. L.; Mocellin, V. J. L.; Morris, L.; Cantin, N.; Shepherd, J.; Sarre, L.; Peng, J.; Liao, Y.; Pickrell, J.; Andolfatto, P. L.; Matz, M. V.; Bay, L. K.; Przeworski, M.

10.1101/867754 — evolutionary biology — Posted on 2019-12-06

2448 Phylogeography of equine infectious anemia virus

Jara, M.; Frias-De-Diego, A.; Machado, G.

10.1101/867747 — evolutionary biology — Posted on 2019-12-06

2449 Functional randomness despite high taxonomic turnover across an elevational gradient in a global biodiversity hotspot: A case study of hawkmoths and birds

Mungee, M.; Athreya, R.

10.1101/867770 — ecology — Posted on 2019-12-06

2450 Climate change and local host availability drive the northern range boundary in the rapid northward expansion of the eastern giant swallowtail butterfly

Wilson, J. K.; Casajus, N.; Hutchinson, R. A.; McFarland, K. P.; Kerr, J. T.; Berteaux, D.; Larrivee, M.; Prudic, K. L.

10.1101/868125 — ecology — Posted on 2019-12-06

2451 HIV-DRLink: A tool for detecting linked HIV-1 drug resistance mutations in next generation sequencing data

Shao, W.; Boltz, V. F.; Hattori, J.; Bale, M. J.; Maldarelli, F.; Coffin, J. M.; Kearney, M. F.

10.1101/866715 — bioinformatics — Posted on 2019-12-06

2452 Genomic evidence for global ocean plankton biogeography shaped by large-scale current systems

Richter, D. J.; Watteaux, R.; Vannier, T.; Leconte, J.; Fremont, P.; Reygondeau, G.; Maillet, N.; Henry, N.; Benoit, G.; Fernandez-Guerra, A.; Suweis, S.; Narci, R.; Berney, C.; Eveillard, D.; Gavory, F.; Guidi, L.; Labadie, K.; Mahieu, E.; Poulain, J.; Romac, S.; Roux, S.; Dimier, C.; Kandels, S.; Picheral, M.; Searson, S.; Tara Oceans Coordinators, ; Pesant, S.; Aury, J.-M.; Brum, J. R.; Lemaitre, C.; Pelletier, E.; Bork, P.; Sunagawa, S.; Karp-Boss, L.; Bowler, C.; Sullivan, M. B.; Karsenti, E.; Mariadassou, M.; Probert, I.; Peterlongo, P.; Wincker, P.; de Vargas, C.; Ribera d'Alcal

10.1101/867739 — ecology — Posted on 2019-12-06

2453 Lgl cortical dynamics are independent of binding to the Scrib-Dlg complex but require Dlg-dependent restriction of aPKC

Ventura, G.; Moreira, S.; Barros-Carvalho, A.; Osswald, M.; Morais-de-Sa, E.

10.1101/867929 — developmental biology — Posted on 2019-12-06

2454 Characterization, modelling and mitigation of gene expression burden in mammalian cells

Frei, T.; Cella, F.; Tedeschi, F.; Gutierrez, J.; Stan, G.-B.; Khammash, M.; Siciliano, V.

10.1101/867549 — synthetic biology — Posted on 2019-12-06

2455 Longitudinal change in executive function is associated with impaired top-down frontolimbic regulation during reappraisal in older adults

Lloyd, W.; Morriss, J.; Macdonald, B.; Joanknecht, K.; Sigurd, J.; van Reekum, C.

10.1101/867689 — neuroscience — Posted on 2019-12-06

2456 Local nucleosome dynamics and eviction following a double-strand break are reversible by NHEJ-mediated repair in the absence of DNA replication

Tripuraneni, V.; Memisoglu, G.; Zhu, W.; Tran, T.; Hartemink, A. J.; Haber, J. E.; MacAlpine, D. M.

10.1101/866673 — genomics — Posted on 2019-12-06

2457 Does breeding season variation affect evolution of a sexual signaling trait in a tropical lizard clade?

Gray, L. N.; Barley, A. J.; Hillis, D. M.; Pavon-Vazquez, C. J.; Poe, S.; White, B. A.

10.1101/864132 — evolutionary biology — Posted on 2019-12-06

2458 Environment affects specialisation of plants and pollinators

Cagua, E. F.; Lustig, A.; Tylianakis, J. M.; Stouffer, D. B.

10.1101/866772 — ecology — Posted on 2019-12-06

2459 Distinct activities of Scrib module proteins organize epithelial polarity

Khoury, M. J.; Bilder, D.

10.1101/866863 — developmental biology — Posted on 2019-12-06

2460 In situ SAXS of protein deposits in Alzheimer's disease

Makowski, L.; Roig Solvas, B.; Hyman, B. T.

10.1101/868273 — neuroscience — Posted on 2019-12-06

2461 Contacting domains that segregate lipid from solute transporters in malaria parasites

Garten, M.; Beck, J. R.; Roth, R.; Tenkova-Heuser, T.; Heuser, J.; Bleck, C. K.; Goldberg, D. E.; Zimmerberg, J.

10.1101/863993 — microbiology — Posted on 2019-12-06

2462 Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration.

Revez, J. A.; Lin, T.; Qiao, Z.; Xue, A.; Holtz, Y.; Zhu, Z.; Zeng, J.; Wang, H.; Sidorenko, J. J.; Kemper, K. E.; Vinkhuyzen, A. A. E.; Frater, J.; Eyles, D.; Burne, T. H. J.; Mitchell, B.; Martin, N. G.; Zhu, G.; Visscher, P. M.; Yang, J.; Wray, N. R.; McGrath, J. J.

10.1101/860767 — genetics — Posted on 2019-12-06

2463 The secreted acid phosphatase domain-containing GRA44 from Toxoplasma gondii is required for C-myc induction in infected cells

Blakely, W. J.; Holmes, M. J.; Arrizabalaga, G.

10.1101/867614 — microbiology — Posted on 2019-12-06

2464 Variation in cell surface hydrophobicity among Cryptococcus neoformans strains influences interactions with amoeba

Vij, R.; Crawford, C.; Casadevall, A.

10.1101/867598 — microbiology — Posted on 2019-12-06

2465 Mutations in disordered proteins as early indicators of nucleic acid changes triggering speciation

Forcelloni, S.; Giansanti, A.

10.1101/867648 — evolutionary biology — Posted on 2019-12-06

2466 How much does Ne vary among species?

Galtier, N.; Rousselle, M.

10.1101/861849 — evolutionary biology — Posted on 2019-12-06

2467 Differential tolerance to changes in moisture regime during early infection stages in the fungal pathogen Zymoseptoria tritici

Boixel, A.-L.; Gelisse, S.; Marcel, T. C.; Suffert, F.

10.1101/867572 — microbiology — Posted on 2019-12-06

2468 Mycolactone-independent pathogenicity of Mycobacterium ulcerans: an experimental study in plants.

Bouam, A.; Drancourt, M.

10.1101/867556 — microbiology — Posted on 2019-12-06

2469 Direct ETTIN-auxin interaction controls chromatin state in gynoecium development

Kuhn, A.; Harborough, S. R.; McLaughlin, H.; Kepinski, S.; Ostergaard, L.

10.1101/863134 — plant biology — Posted on 2019-12-06

2470 Anterior cingulate cortex differently modulates fronto-parietal functional connectivity between resting-state and working memory tasks

Di, X.; Zhang, H.; Biswal, B. B.

10.1101/722710 — neuroscience — Posted on 2019-12-06

2471 Human revealed stochastic preferences for multi-component economic choice options

Volkmann, K.; Pastor-Bernier, A.; Stasiak, A.; Grabenhorst, F.; Schultz, W.

10.1101/832881 — neuroscience — Posted on 2019-12-06

2472 Visual Cell Sorting: A High-throughput, Microscope-based Method to Dissect Cellular Heterogeneity

Hasle, N.; Cooke, A.; Srivatsan, S.; Huang, H.; Stephany, J. J.; Krieger, Z.; Jackson, D. L.; Tang, W.; Monnat, R. J.; Trapnell, C.; Hatch, E. M.; Fowler, D.

10.1101/856476 — molecular biology — Posted on 2019-12-06

2473 Genomics of local adaptation in blue tit

Perrier, C.; Rougemont, Q.; Charmantier, A.

10.1101/864975 — evolutionary biology — Posted on 2019-12-06

2474 Free water: a sensitive metric for age-related modifications of the cingulum white matter and its association with cognition

Edde, M.; Theaud, G.; Rheault, F.; Dilharreguy, B.; Helmer, C.; Dartigues, J.-F.; Amieva, H.; Allard, M.; Descoteaux, M.; Catheline, G.

10.1101/867606 — neuroscience — Posted on 2019-12-06

2475 Quantification of translation uncovers the functions of the alternative transcriptome

Calviello, L.; Hirsekorn, A.; Ohler, U.

10.1101/608794 — genomics — Posted on 2019-12-06

2476 Comparing current noise in biological and solid-state nanopores

Fragasso, A.; Schmid, S.; Dekker, C.

10.1101/866384 — biophysics — Posted on 2019-12-06

2477 Pathogen transmission from vaccinated hosts can cause dose-dependent reduction in virulence

Bailey, R. I.; Cheng, H. H.; Chase-Topping, M.; Mays, J. K.; Anacleto, O.; Dunn, J. R.; Doeschl-Wilson, A.

10.1101/830570 — microbiology — Posted on 2019-12-06

2478 Anxiety, avoidance, and sequential evaluation

Zorowitz, S.; Momennejad, I.; Daw, N. D.

10.1101/724492 — neuroscience — Posted on 2019-12-06

2479 Space is the Place: Effects of Continuous Spatial Structure on Analysis of Population Genetic Data

Battey, C. J.; Ralph, P. L.; Kern, A. D.

10.1101/659235 — genetics — Posted on 2019-12-06

2480 Core spliceosomal Sm proteins as constituents of cytoplasmic mRNPs in plants.

Hyjek-Skladanowska, M.; Bajczyk, M.; Golebiewski, M.; Nuc, P.; Kolowerzo-Lubnau, A.; Jarmolowski, A.; Smolinski, D. J.

10.1101/709550 — cell biology — Posted on 2019-12-06

2481 Chromosome Haplotype Determination and Single-Chromosome Analysis

Tourdot, R.; Zhang, C.-Z.

10.1101/629337 — genomics — Posted on 2019-12-06

2482 Flexible mixture model approaches that accommodate footprint size variability for robust detection of balancing selection

Cheng, X.; DeGiorgio, M.

10.1101/645887 — evolutionary biology — Posted on 2019-12-06

2483 Human lateral Frontal Pole contributes to control over social-emotional behaviour

Bramson, B.; Folloni, D.; Verhagen, L.; Hartogsveld, B.; Mars, R. B.; Toni, I.; Roelofs, K.

10.1101/584896 — neuroscience — Posted on 2019-12-06

2484 The Phlebotomus papatasi transcriptomic response to trypanosomatid-contaminated blood is robust but non-specific

Sloan, M. A.; Sadlova, J.; Lestinova, T.; Sanders, M.; Cotton, J. A.; Volf, P.; Ligoxygakis, P.

10.1101/867382 — immunology — Posted on 2019-12-06

2485 DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis

Nassar, Z. D.; Mah, C. Y.; Dehairs, J.; Burvenich, I. J. G.; Irani, S.; Centenera, M. M.; Shrestha, R. K.; Moldovan, M.; Don, A. S.; Scott, A. M.; Horvath, L. G.; Lynn, D. J.; Selth, L. A.; Hoy, A. J.; Swinnen, J. V.; Butler, L. M.

10.1101/865626 — cancer biology — Posted on 2019-12-06

2486 Sierra: Discovery of differential transcript usage from polyA-captured single-cell RNA-seq data

Patrick, R.; Humphreys, D.; Oshlack, A.; Ho, J. W. K.; Harvey, R. P.; Lo, K. K.

10.1101/867309 — bioinformatics — Posted on 2019-12-06

2487 Learning from Synthetic Dataset for Crop Seed Instance Segmentation

Toda, Y.; Okura, F.; Ito, J.; Okada, S.; Kinoshita, T.; Tsuji, H.; Saisho, D.

10.1101/866921 — bioinformatics — Posted on 2019-12-06

2488 Mental state space visualization for interactive modeling of personalized BCI control strategies

Kuzovkin, I.; Tretyakov, K.; Uusberg, A.; Vicente, R.

10.1101/867119 — neuroscience — Posted on 2019-12-06

2489 Learning cognitive maps for vicarious evaluation

Rikhye, R. V.; Gothoskar, N.; Guntupalli, J. S.; Dedieu, A.; Lazaro-Gredilla, M.; George, D.

10.1101/864421 — neuroscience — Posted on 2019-12-06

2490 The virus integrations in gut microbes associated with dysbiosis of microbial community in tumorigenesis of colorectal carcinoma

Cui, B.; Wang, X.; Xu, W.; Zheng, C.; Cai, J.

10.1101/867291 — microbiology — Posted on 2019-12-06

2491 Differential oxidative costs of locomotory and genital damage in an orb-weaving spider

Mouginot, P.; Uhl, G.; Toshkova, N.; Beaulieu, M.

10.1101/867325 — evolutionary biology — Posted on 2019-12-06

2492 FUNCTIONAL NETWORK CONNECTIVITY (FNC)-BASED GENERATIVE ADVERSARIAL NETWORK (GAN) AND ITS APPLICATIONS IN MENTAL DISORDERS DIAGNOSIS

Zhao, J.; Zhi, D.; Yan, W.; Vince, C. D.; Sui, J.

10.1101/867168 — bioengineering — Posted on 2019-12-06

2493 Cell-to-cell variability in JAK2/STAT5 pathway components and cytoplasmic volumes define survival threshold in erythroid progenitor cells

Adlung, L.; Stapor, P.; Schmiester, L.; Schwarzmueller, L.; Wang, D.; Timmer, J.; Klingmueller, U.; Hasenauer, J.; Schilling, M.

10.1101/866871 — systems biology — Posted on 2019-12-06

2494 A longitudinal study of perceived stress and cortisol responses in an undergraduate student population from India

Batabyal, A.; Bhattacharya, A.; Thaker, M.; Mukherjee, S.

10.1101/867184 — physiology — Posted on 2019-12-06

2495 Identifying Brain Network Topology Changes in Task Processes and Psychiatric Disorders

Rezaeinia, P.; Fairley, K.; Pal, P.; Meyer, F.; Carter, R. M.

10.1101/866855 — neuroscience — Posted on 2019-12-06

2496 Functional connectivity differences in early infancy precede autism symptoms: a multivariate pattern analysis

Dickinson, A.; Daniel, M.; Marin, A.; Goanker, B.; Dapretto, M.; McDonald, N. M.; Jeste, S.

10.1101/866939 — neuroscience — Posted on 2019-12-06

2497 d-Lysergic acid diethylamide has major potential as a cognitive enhancer

Cini, F. A.; Ornelas, I.; Marcos, E.; Goto-Silva, L.; Nascimento, J.; Ruschi, S.; Salerno, J.; Karmirian, K.; Costa, M.; Sequerra, E.; de Araujo, D. B.; Tofoli, L. F.; Renno-Costa, C.; Martins-de-Souza, D.; Feilding, A.; Rehen, S.; Ribeiro, S.

10.1101/866814 — neuroscience — Posted on 2019-12-06

2498 Heme uptake in Lactobacillus sakei evidenced by a new ECF-like transport system.

Verplaetse, E.; Andre-Leroux, G.; Duhutrel, P.; Coeuret, G.; Chaillou, S.; Nielsen-Leroux, C.; Champomier-Verges, M.-C.

10.1101/864751 — microbiology — Posted on 2019-12-06

2499 Naturally Occurring Polymorphisms in Human Cytomegalovirus gO Exert Epistatic Influences on Cell-Free and Cell-To-Cell Spread, and Antibody Neutralization on gH Epitopes.

Day, L. Z.; Stegmann, C.; Schultz, E. P.; Lanchy, J.-M.; Yu, Q.; Ryckman, B. J.

10.1101/867234 — microbiology — Posted on 2019-12-06

2500 Gut-associated bacteria invade the midgut epithelium of Aedes aegypti and stimulate innate immunity and suppress Zika virus infection in cells.

Hegde, S.; Voronin, D.; Casas-Sanchez, A.; Saldana, M.; Acosta-Serrano, A.; Popov, V. L.; Chopra, A. K.; Hughes, G. L.

10.1101/866897 — microbiology — Posted on 2019-12-06

2501 Early replacement of West Eurasian male Y chromosomes from the east

Hallast, P.; Agdzhoyan, A.; Balanovsky, O.; Xue, Y.; Tyler-Smith, C.

10.1101/867317 — genetics — Posted on 2019-12-06

2502 An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease

Ruotsalainen, S. E.; Partanen, J.; Cichonska, A.; Lin, J.; Benner, C.; Surakka, I.; Reeve, M. P.; Palta, P.; Salmi, M.; Jalkanen, S.; Ahola-Olli, A.; Palotie, A.; Salomaa, V.; Daly, M.; Pirinen, M.; Koskela, J.; Ripatti, S.

10.1101/867267 — genetics — Posted on 2019-12-06

2503 A new symbiotic lineage related to Neisseria and Snodgrassella arises from the dynamic and diverse microbiomes in sucking lice

Rihova, J.; Batani, G.; Rodriguez-Ruano, S. M.; Martinu, J.; Novakova, E.; Hypsa, V.

10.1101/867275 — evolutionary biology — Posted on 2019-12-06

2504 Plant cheaters preferentially target arbuscular mycorrhizal fungi that are highly connected to mutualistic plants

Gomes, S.; Fortuna, M.; Bascompte, J.; Merckx, V.

10.1101/867259 — ecology — Posted on 2019-12-06

2505 A FIJI Macro for quantifying pattern in extracellular matrix

Wershof, E.; Barry, D. J.; Jenkins, R. P.; Rullan, A.; Wilkins, A.; Roxanis, I.; Anderson, K. I.; Park, D.; Bates, P. A.; Sahai, E.

10.1101/867507 — cancer biology — Posted on 2019-12-06

2506 Modelling heterogeneities in the cross-linked bacterial sacculus

Rani, G.; Patri, I.

10.1101/867176 — biophysics — Posted on 2019-12-06

2507 Effect of Assembly Method on Nanoparticle Attachment Density, Growth Rate, and Motility of Nanoscale Bacteria Enabled Autonomous Drug Delivery System (NanoBEADS)

Zhan, Y.; Fergusson, A.; McNally, L. R.; Davis, R. M.; Behkam, B.

10.1101/867101 — bioengineering — Posted on 2019-12-06

2508 Long-read only assembly of Drechmeria coniospora genomes reveals widespread chromosome plasticity and illustrates the limitations of current nanopore methods

Courtine, D.; Provaznik, J.; Reboul, J.; Blanc, G.; Benes, V.; Ewbank, J. J.

10.1101/866020 — genomics — Posted on 2019-12-06

2509 Integrative analysis and machine learning based characterization of single circulating tumor cells

Iyer, A.; Gupta, K.; Sharma, S.; Hari, K.; Lee, Y. F.; Ramalingam, N.; Yap, Y. S.; West, J.; Bhagat, A. A.; Subramani, B. V.; Sabuwala, B.; Tan, T. Z.; Thiery, J. P.; Jolly, M. K.; Ramalingam, N.; Sengupta, D.

10.1101/867200 — genomics — Posted on 2019-12-06

2510 Dispersal behaviour as the outcome and trigger of multilevel selection in a social spider

Vasarhelyi, Z. A.; Pruitt, J. N.; Scheuring, I.

10.1101/866038 — evolutionary biology — Posted on 2019-12-06

2511 CellCountCV - a web-application for accurate cell counting and automated batch processing of microscopy images using fully-convolutional neural networks

Antonets, D. V.; Russkikh, N. E.; Sanchez, A.; Kovalenko, V. R.; Bairamova, E. M.; Shtokalo, D. N.; Medvedev, S. P.; Zakian, S. M.

10.1101/867218 — cell biology — Posted on 2019-12-06

2512 The ER cargo receptor SURF4 facilitates efficient erythropoietin secretion

Lin, Z.; King, R.; Tang, V.; Myers, G.; Balbin-Cuesta, G.; Friedman, A.; McGee, B.; Desch, K.; Ozel, A. B.; Siemieniak, D.; Reddy, P.; Emmer, B.; Khoriaty, R.

10.1101/866954 — cell biology — Posted on 2019-12-06

2513 ReferenceSeeker: rapid determination of appropriate reference genomes

Schwengers, O.; Hain, T.; Chakraborty, T.; Goesmann, A.

10.1101/863621 — bioinformatics — Posted on 2019-12-06

2514 Global atlas tree of natural proteins based on sorted composition vectors

Tian, P.

10.1101/866103 — bioinformatics — Posted on 2019-12-06

2515 Juvenile hormone regulation on the flight capability of Bactrocera dorsalis (Diptera: Tephritidae)

Chen, P.; Chen, M.; Ye, H.; Yuan, R.; Du, C.; Ong, S. P.

10.1101/867085 — animal behavior and cognition — Posted on 2019-12-06

2516 ADP is the dominant controller of AMP-activated protein kinase activity dynamics in skeletal muscle during exercise

Coccimiglio, I. F.; Clarke, D. C.

10.1101/861641 — systems biology — Posted on 2019-12-06

2517 Why some size illusions affect grip aperture

Smeets, J.; Kleijn, E.; van der Meijden, M.; Brenner, E.

10.1101/866640 — neuroscience — Posted on 2019-12-06

2518 'Awake delta' and theta-rhythmic hippocampal network modes during intermittent locomotor behaviors in the rat

Schultheiss, N. W.; Schlecht, M.; Jayachandran, M.; Brooks, D. R.; McGlothan, J. L.; Guilarte, T. R.; Allen, T. A.

10.1101/866962 — neuroscience — Posted on 2019-12-06

2519 The economy of anatomy: Discovering the turbulent homogeneous isotropic functional core organisation of the human brain

Deco, G.; Kringelbach, M. L.

10.1101/865923 — neuroscience — Posted on 2019-12-06

2520 Semiochemical responsive olfactory sensory neurons are sexually dimorphic and plastic

Vihani, A.; Hu, X. S.; Gundala, S.; Koyama, S.; Block, E.; Matsunami, H.

10.1101/867044 — neuroscience — Posted on 2019-12-06

2521 Functional reorganization of brain networks across the human menstrual cycle

Pritschet, L.; Santander, T.; Layher, E.; Taylor, C. M.; Yu, S.; Miller, M. B.; Grafton, S. T.; Jacobs, E. G.

10.1101/866913 — neuroscience — Posted on 2019-12-06

2522 Thiamine pyrophosphate riboswitches in Bacteroides species regulate transcription or translation of thiamine transport and biosynthesis genes

Costliow, Z. A.; Degnan, P. H.; Vanderpool, C. K.

10.1101/867226 — microbiology — Posted on 2019-12-06

2523 Dinoflagellate symbionts escape vomocytosis by host cell immune suppression

Jacobovitz, M. R.; Rupp, S.; Voss, P. A.; Gornik, S. G.; Guse, A.

10.1101/864579 — microbiology — Posted on 2019-12-06

2524 Transinfection of buffalo flies (Haematobia exigua) with Wolbachia and effect on host biology

Madhav, M.; Brown, G.; Morgan, J. A. T.; Asgari, S.; McGraw, E. A.; James, P.

10.1101/867093 — microbiology — Posted on 2019-12-06

2525 Forecasting the potential distribution of the invasive vegetable leafminer using "top-down" and "bottom-up" models

Maino, J. L.; Pirtle, E. I.; Ridland, P.; Umina, P. A.

10.1101/866996 — ecology — Posted on 2019-12-06

2526 Membrane dynamics promote sensitivity of epithelial cancer targets to pro-necrotic activity of Natural Killer cells

Zhu, Y.; Xie, J.; Shi, J.

10.1101/867127 — cell biology — Posted on 2019-12-06

2527 Vein Patterning by Tissue-Specific Auxin Transport

Govindaraju, P.; Verna, C.; Zhu, T.; Scarpella, E.

10.1101/866632 — plant biology — Posted on 2019-12-06

2528 Abundant expression of maternal siRNAs is a conserved feature of seed development

Grover, J. W.; Burgess, D. G.; Kendall, T.; Baten, A.; Pokhrel, S.; King, G. J.; Meyers, B. C.; Freeling, M.; Mosher, R. A.

10.1101/866806 — plant biology — Posted on 2019-12-06

2529 Faecal microbiota transplant from aged donor mice into young recipients affects spatial learning and memory

D'Amato, A.; Di Cesare-Mannelli, L.; Lucarini, E.; Man, A. L.; Le Gall, G.; Branca, J. J. V.; Ghelardini, C.; Amedei, A.; Bertelli, E.; Regoli, M.; Pacini, A.; Luciani, G.; Gallina, P.; Altera, A.; Narbad, A.; Gulisano, M.; Hoyles, L.; Vauzour, D.; Nicoletti, C.

10.1101/866459 — neuroscience — Posted on 2019-12-06

2530 An architectonic type principle in the development of laminar patterns of cortico-cortical connections

Beul, S. F.; Goulas, A.; Hilgetag, C. C.

10.1101/866681 — neuroscience — Posted on 2019-12-06

2531 Hotspot Dosages of Most Rapid Antibiotic Resistance Evolution

Reding Roman, R. C.; Catalan, P. C.; Jansen, G.; Rosenstiel, P.; Schulenburg, H.; Gudelj, I.; Beardmore, R. E.

10.1101/866269 — evolutionary biology — Posted on 2019-12-06

2532 Riverscape genetics in brook lamprey: genetic diversity is less influenced by river fragmentation than by gene flow with the anadromous ecotype

Rougemont, Q.; Dolo, V.; Oger, A.; Besnard, A.-L.; Huteau, D.; Coutellec, M.-A.; Perrier, C.; Launey, S.; Evanno, G.

10.1101/866533 — evolutionary biology — Posted on 2019-12-06

2533 Boldness and exploration are linked to shell morph but not environmental context in the snail Cepaea nemoralis

Dahirel, M.; Gaudu, V.; Ansart, A.

10.1101/866947 — ecology — Posted on 2019-12-06

2534 Use of dual electron probes reveals role of ferritin in erythropoiesis

Aronova, M. A.; Noh, S. J.; Zhang, G.; Byrnes, C.; Meier, E. R.; Kim, Y. C.; Leapman, R. D.

10.1101/866889 — cell biology — Posted on 2019-12-06

2535 Trehalose as an alternative to glycerol as a glassing agent for in vivo DNP MRI

Brender, J. R.; Kishimoto, S.; Eaton, G. R.; Eaton, S. S.; Saida, Y.; Krishna, M. C.

10.1101/866665 — biophysics — Posted on 2019-12-06

2536 Data structures based on k-mers for querying large collections of sequencing datasets

Marchet, C.; Boucher, C.; Puglisi, S. J.; Medvedev, P.; Salson, M.; Chikhi, R.

10.1101/866756 — bioinformatics — Posted on 2019-12-06

2537 Prokaryotic Single-Cell RNA Sequencing by In Situ Combinatorial Indexing

Blattman, S. B.; Jiang, W.; Oikonomou, P.; Tavazoie, S.

10.1101/866244 — systems biology — Posted on 2019-12-06

2538 Atrial natriuretic peptide orchestrates a coordinated physiological response to fuel non shivering thermogenesis

Carper, D.; Coue, M.; Nascimento, E. B.; Barquissau, V.; Lagarde, D.; Pestourie, C.; Laurens, C.; Vily-Petit, J.; Soty, M.; Monbrun, L.; Marques, M.-A.; Jeanson, Y.; Sainte-Marie, Y.; Mairal, A.; Dejean, S.; Tavernier, G.; Viguerie, N.; Bourlier, V.; Lezoualc'h, F.; Carriere, A.; Saris, W. H. M.; Astrup, A.; Casteilla, L.; Mithieux, G.; van Marken Lichtenbelt, W. D.; Langin, D.; Schrauwen, P.; Moro, C.

10.1101/866277 — physiology — Posted on 2019-12-06

2539 Auditory Cortex Tracks Masked Acoustic Onsets in Background Speech: Evidence for Early Cortical Stream Segregation

Brodbeck, C.; Jiao, A.; Hong, L. E.; Simon, J. Z.

10.1101/866749 — neuroscience — Posted on 2019-12-06

2540 Reversible loss of Hippocampal Function in a Mouse Model of Demyelination/Remyelination

Das, A.; Bastian, C.; Trestan, L.; Suh, J.; Dey, T.; Trapp, B.; Baltan, S.; Dana, H.

10.1101/866723 — neuroscience — Posted on 2019-12-06

2541 Systemic Treatment with Nicotinamide Riboside is Protective in Three Mouse Models of Retinal Degeneration

Zhang, X.; Henneman, N. F.; Girardot, P. E.; Sellers, J. T.; Chrenek, M. A.; Li, Y.; Wang, J.; Brenner, C. M.; Nickerson, J. M.; Boatright, J.

10.1101/866798 — molecular biology — Posted on 2019-12-06

2542 Evaluation of the impact of Shigella virulence genes on the basis of clinical features observed in patients with shigellosis

Chowdhury, V. P.; Azmi, I. J.; Islam, M. R.; Akter, M.; Mahmud, S.; Faruque, A. S. G.; Talukder, K. A.

10.1101/865832 — microbiology — Posted on 2019-12-06

2543 Exploiting homologous recombination increases SATAY efficiency for loss- and gain-of-function screening

Michel, A. H.; van Schie, S.; Mosbach, A.; Scalliet, G.; Kornmann, B.

10.1101/866483 — cell biology — Posted on 2019-12-06

2544 CX3CL1 oligomerization is required for efficient CX3CR1-specific cell adherence

Ostuni, M. A.; Hermand, P.; Saindoy, E.; Guillou, N.; Coens, A.; Hattab, C.; Mandon, E.; Jawhari, A.; Iatmanen-Harbi, S.; Lequin, O.; Fuchs, P.; Lacapere, J.-J.; Combadiere, C.; Pincet, F.; Deterre, P.

10.1101/865998 — cell biology — Posted on 2019-12-06

2545 Linear alkylbenzenes (LABs) as sewage pollution indicators in the aquatic ecosystem of Peninsular Malaysia

AL-KHADHER, S.; Abdul Kadir, A.; Pauzi Zakaria, M.

10.1101/863647 — biochemistry — Posted on 2019-12-06

2546 In silicon emergence of an autonomous artificial metabolic system

Chen, S.

10.1101/865808 — systems biology — Posted on 2019-12-06

2547 Ecophysiological traits of a clonal grass in its climate change response

Kosova, V.; Hajek, T.; Hadincova, V.; Munzbergova, Z.

10.1101/864827 — plant biology — Posted on 2019-12-06

2548 Low-Latitude Origins of the Four Phanerozoic Evolutionary Faunas

Rojas, A.; Calatayud, J.; Kowalewski, M.; Neuman, M.; Rosvall, M.

10.1101/866186 — paleontology — Posted on 2019-12-06

2549 Serial assessment of iron in the motor cortex in limb-onset Amyotrophic Lateral Sclerosis using Quantitative Susceptibility Mapping

Bhattarai, A.; Chen, Z.; Ward, P. G. D.; Talman, P.; Mathers, S.; Phan, T. G.; Chapman, C.; Howe, J.; Lee, S.; Lie, Y.; Egan, G. F.; Chua, P.

10.1101/865709 — neuroscience — Posted on 2019-12-06

2550 Standardized Effect Sizes and Image-Based Meta-Analytical Approaches for fMRI Data.

Bossier, H.; Nichols, T. E.; Moerkerke, B.

10.1101/865881 — neuroscience — Posted on 2019-12-06

2551 Skill Acquisition is Enhanced by Reducing Trial-To-Trial Repetition

Vleugels, L. W.; Swinnen, S. P.; Hardwick, R. M.

10.1101/866046 — neuroscience — Posted on 2019-12-06

2552 Oxytocin shapes spontaneous activity patterns in the developing visual cortex by activating somatostatin interneurons

Maldonado, P. P.; Nuno-Perez, A.; Kirchner, J.; Hammock, E.; Gjorgjieva, J.; Lohmann, C.

10.1101/866251 — neuroscience — Posted on 2019-12-06

2553 An illustration of reproducibility in neuroscience research in the absence of selective reporting

Kong, X.-Z.; ENIGMA Laterality Working Group, ; Francks, C.

10.1101/866301 — neuroscience — Posted on 2019-12-06

2554 Neuropsychiatric mutations delineate functional brain connectivity dimensions contributing to autism and schizophrenia

Moreau, C.; Urchs, S.; Orban, P.; Schramm, C.; Dumas, G.; Labbe, A.; Huguet, G.; Douard, E.; Quirion, P.-O.; Lin, A.; Kushan, L.; Grot, S.; Luck, D.; Mendrek, A.; Potvin, S.; Stip, E.; Bourgeron, T.; Evans, A. C.; SimonsVIP Consortium, ; Bearden, C. E.; Bellec, P.; Jacquemont, S.

10.1101/862615 — neuroscience — Posted on 2019-12-06

Aquino, T. G.; Minxha, J.; Dunne, S.; Ross, I. B.; Mamelak, A. N.; Rutishauser, U.; O'Doherty, J. P.

10.1101/865568 — neuroscience — Posted on 2019-12-06

2556 The structure of bacteriophage T5 injection stop signal.

Davison, J.

10.1101/866236 — microbiology — Posted on 2019-12-06

2557 Genome-wide analysis of DNA uptake by naturally competent Haemophilus influenzae

Mora, M.; Mell, J. C.; Ehrlich, G. D.; Ehrlich, R.; Redfield, R. J.

10.1101/866426 — microbiology — Posted on 2019-12-06

2558 Multivariable G-E interplay in the prediction of educational achievement

Allegrini, A. G.; Karhunen, V.; Coleman, J. R.; Selzam, S.; Rimfeld, K.; von Stumm, S.; Pingault, J.-B.; Plomin, R.

10.1101/865360 — genetics — Posted on 2019-12-06

2559 Controlling the speed and trajectory of evolution with counterdiabatic driving

Iram, S.; Dolson, E.; Chiel, J.; Pelesko, J.; Krishnan, N.; Güngör, O.; Kuznets-Speck, B.; Deffner, S.; Ilker, E.; Scott, J. G.; Hinczewski, M.

10.1101/867143 — evolutionary biology — Posted on 2019-12-06

2560 Whole genome sequencing of Herpes Simplex Virus 1 directly from human cerebrospinal fluid reveals selective constraints in neurotropic viruses.

Lassalle, F.; Beale, M. A.; Bharucha, T.; Williams, C. A.; Williams, R. J.; Cudini, J.; Goldstein, R. A.; Haque, T.; Depledge, D. P.; Breuer, J.

10.1101/866350 — evolutionary biology — Posted on 2019-12-06

2561 Growth and mortality of the oak processionary moth, Thaumetopoea processionea L., on two oak species: direct and trait-mediated effects of host and neighbour species identity

Damestoy, T.; Moreira, X.; Jactel, H.; Valdes-Correcher, E.; Plomion, C.; Castagneyrol, B.

10.1101/865253 — ecology — Posted on 2019-12-06

2562 GHSR-1a is not Required for Ghrelin's Anti-inflammatory and Fat-sparing Effects in Cancer Cachexia

Liu, H.; Luo, J.; Guillory, B.; Chen, J.-a.; Zang, P.; Yoeli, J. K.; Hernandez, Y.; Lee, I.; Anderson, B.; Storie, M. J.; Tewnion, A.; Garcia, J.

10.1101/866376 — cancer biology — Posted on 2019-12-06

2563 LandScape: a web application for interactive genomic summary visualization

Jia, W.; Li, H.; Li, S.; Li, S.

10.1101/866087 — bioinformatics — Posted on 2019-12-06

2564 Mitral valve leaflet response to ischemic mitral regurgitation: From gene expression to tissue remodeling

Howsmon, D. P.; Rego, B. V.; Castillero, E.; Ayoub, S.; Khalighi, A. H.; Gorman, R. C.; Gorman, J. H.; Ferrari, G.; Sacks, M. S.

10.1101/864876 — bioengineering — Posted on 2019-12-06

2565 Inference and visualization of phenome-wide causal relationships using genetic data: an application to dental caries and periodontitis.

Haworth, S.; Kho, P. F.; Holgerson, P. L.; Hwang, L.-D.; Timpson, N. J.; Renteria, M. E.; Johansson, I.; Cuellar Partida, G.

10.1101/865956 — genetics — Posted on 2019-12-06

2566 Why are education, socioeconomic position and intelligence genetically correlated?

Morris, T. T.; Davies, N. M.; Hemani, G.; Davey Smith, G.

10.1101/630426 — genetics — Posted on 2019-12-06

2567 Changing the Waddington landscape to control mesendoderm competence

Valcourt, J. R.; Huang, R.; Kundu, S.; Venkatasubramanian, D.; Kingston, R. E.; Ramanathan, S.

10.1101/867010 — developmental biology — Posted on 2019-12-06

2568 Antibiotic transport kinetics in Gram-negative bacteria revealed via single-cell uptake analysis and mathematical modelling

Cama, J.; Voliotis, M.; Metz, J.; Smith, A.; Iannucci, J.; Keyser, U. F.; Tsaneva-Atanasova, K.; Pagliara, S.

10.1101/645507 — biophysics — Posted on 2019-12-06

2569 Pooled CRISPR Inverse PCR sequencing (PCIP-seq): simultaneous sequencing of retroviral insertion points and the integrated provirus with long reads

Artesi, M.; Hahaut, V.; Cole, B.; Lambrechts, L.; Ashrafi, F.; Marcais, A.; Hermine, O.; Griebel, P.; Arsic, N.; van der Meer, F.; Burny, A.; Bron, D.; Bianchi, E.; Delvenne, P.; Bours, V.; Charlier, C.; Georges, M.; Vandekerckhove, L.; Van den Broeke, A.; Durkin, K.

10.1101/558130 — genomics — Posted on 2019-12-06

2570 Targeting cardiac myocyte Na+ pump function with β3 adrenergic agonist in rabbits and patients with severe congestive heart failure

Fry, N. A. S.; Liu, C.-C.; Garcia, A.; Hamilton, E. J.; Karimi Galougahi, K.; Kim, Y. J.; Harris, J. L.; Nelson, G. I. C.; Whalley, D. W.; Bundgaard, H.; Rasmussen, H. H.

10.1101/804245 — physiology — Posted on 2019-12-06

2571 A revised mechanism of action of hyperaldosteronism-linked mutations in cytosolic domains of GIRK4 (KCNJ5).

Shalomov, B.; Handklo-Jamal, R.; Reddy, H. P.; Theodor, N.; Bera, A. K.; Dascal, N.

10.1101/866202 — physiology — Posted on 2019-12-06

2572 Horizontal transfer and gene loss shaped the evolution of alpha-amylases in bilaterians

Desiderato, A.; Barbeitos, M.; Gilbert, C.; Da Lage, J.-L.

10.1101/670273 — evolutionary biology — Posted on 2019-12-06

2573 Multiscale mechanical model for cell division orientation in developing biological systems

Leggio, B.; Laussu, J.; Faure, E.; Lemaire, P.; Godin, C.

10.1101/785337 — biophysics — Posted on 2019-12-06

2574 Sensing Traction Force on Matrix Induces Cell-Cell Distant Mechanical Communications for Self-assembly

Ouyang, M.; Qian, Z.; Bu, B.; Jin, Y.; Wang, J.; Liu, L.; Pan, Y.; Deng, L.

10.1101/866228 — biophysics — Posted on 2019-12-06

2575 Anticipatory Control of Momentum for Bipedal Walking on Uneven Terrain

Darici, O.; Temeltas, H.; Kuo, A.

10.1101/769828 — bioengineering — Posted on 2019-12-06

2576 Mindfulness meditation changes the boundary and configuration of the primary functional networks in the brain

Kajimura, S.; Masuda, N.; Lau, J. K.; Murayama, K.

10.1101/664573 — neuroscience — Posted on 2019-12-06

2577 Context-dependent multiplexing by individual VTA dopamine neurons

Kremer, Y.; Flakowski, J.; Rohner, C.; Lüscher, C.

10.1101/408062 — neuroscience — Posted on 2019-12-06

2578 Drosophila models of pathogenic copy-number variant genes show global and non-neuronal defects during development

Yusuff, T.; Jensen, M.; Yennawar, S.; Pizzo, L.; Karthikeyan, S.; Gould, D. J.; Sarker, A.; Matsui, Y.; Iyer, J.; Lai, Z.-C.; Girirajan, S.

10.1101/855338 — genomics — Posted on 2019-12-06

2579 A Homogeneous SIRPα-CD47 Cell-Based, Ligand-Binding Assay: Utility for Small Molecule Drug Development in Immuno-oncology.

Burgess, T.; Amason, J.; Rubin, J.; Duveau, D.; Lamy, L.; Roberts, D.; Farrell, C.; Inglese, J.; Thomas, C.; Miller, T. W.

10.1101/866145 — immunology — Posted on 2019-12-05

2580 Finding valuable bioactive components from Jerusalem artichoke (Helianthus tuberosus L.) leaf protein concentrate in a green biorefinery concept

Kaszas, L.; Alshaal, T.; El-Ramady, H.; Kovacs, Z.; Koroknai, J.; Elhawat, N.; Nagy, E.; Cziaky, Z.; Fari, M.; Domokos-Szabolcsy, E.

10.1101/866178 — plant biology — Posted on 2019-12-05

2581 Molecular Docking Studies of Phytochemicals of Allophylus serratus Against Cyclooxygenase-2 Enzyme

Jemal, K.

10.1101/866152 — pharmacology and toxicology — Posted on 2019-12-05

2582 Women and Men Were Proportionally Represented Among Speakers at Major National Neurology Conferences in 2017

McDermott, M.; Burke, J. F.; McCalpin, H.; Shelgikar, A. V.; Gelb, D. J.; Dunn, A.; Beimer, N. J.; London, Z. N.

10.1101/866160 — neuroscience — Posted on 2019-12-05

2583 Effect of pretreatment with different MMP inhibitors on shear bond strength of composite to primary teeth dentin after six months of aging

Parsaie, Z.; Mohammadi, N.; Firouzmandi, M.

10.1101/866129 — molecular biology — Posted on 2019-12-05

2584 Estimation of Genetic Diversity in Genus Mentha Collected From Azad Jammu And Kashmir, Pakistan

Abasi, F. -; Ahmad, I. -; Khan, S. U.; Ahmed, K. S.; Ulfat, A. -; Khurshid, R. -; Nazia Kamal,

10.1101/866111 — genetics — Posted on 2019-12-05

2585 Biophysical analysis of Plasmodium falciparum Hsp70-Hsp90 organizing protein (PfHop) reveals a monomer that is characterised by folded segments connected by flexible linkers

Shonhai, A.; Makumire, S.; Zininga, T.; Vahokoski, J.; Kursula, I.

10.1101/866137 — biochemistry — Posted on 2019-12-05

2586 Plant community functional composition and diversity drive fine-scale variability in carbon cycling in the tundra

Happonen, K.; Virkkala, A.-M.; Kemppinen, J.; Niittynen, P.; Luoto, M.

10.1101/865899 — ecology — Posted on 2019-12-05

2587 A revised mechanism of action of hyperaldosteronism-linked mutations in cytosolic domains of GIRK4 (KCNJ5).

Shalomov, B.; Handklo-Jamal, R.; Reddy, H. P.; Theodor, N.; Bera, A. K.; Dascal, N.

10.1101/866202 — physiology — Posted on 2019-12-05

2588 Novel Analgesic Agents Obtained by Molecular Hybridization of Orthosteric and Allosteric Ligands

Matera, C.; Flammini, L.; Riefolo, F.; Domenichini, G.; De Amici, M.; Barocelli, E.; Dallanoce, C.; Bertoni, S.

10.1101/866012 — pharmacology and toxicology — Posted on 2019-12-05

2589 Comparison of intradermal injection and epicutaneous laser microporation for anti-tumor vaccine delivery in a human skin explant model

Duinkerken, S.; Lubbers, J.; Stolk, D. A.; Vree, J.; Ambrosini, M.; Kalay, H.; van Kooyk, Y.

10.1101/861930 — immunology — Posted on 2019-12-05

2590 From Modulated Noise to Natural Speech: the Effect of Stimulus Parameters on the Frequency Following Response

Van Canneyt, J.; Wouters, J.; Francart, T.

10.1101/864934 — neuroscience — Posted on 2019-12-05

2591 Acute lymph node slices are a functional model system to study immunity ex vivo

Belanger, M. C.; Kinman, A. W. L.; Catterton, M. A.; Ball, A. G.; Groff, B. D.; Melchor, S. J.; Lukens, J. R.; Ross, A. E.; Pompano, R. R.

10.1101/865543 — immunology — Posted on 2019-12-05

2592 Widespread use of the "ascidian" mitochondrial genetic code in tunicates

Pichon, J.; Luscombe, N. M.; Plessy, C.

10.1101/865725 — genomics — Posted on 2019-12-05

2593 Changes in subjective preference do not require dopamine signaling or the orbital frontal cortex

Lefner, M. J.; Magnon, A. P.; Gutierrez, J. M.; Lopez, M. R.; Wanat, M. J.

10.1101/865436 — neuroscience — Posted on 2019-12-05

2594 Quantifying Aphantasia through drawing: Those without visual imagery show deficits in object but not spatial memory

Bainbridge, W. A.; Pounder, Z.; Eardley, A. F.; Baker, C. I.

10.1101/865576 — neuroscience — Posted on 2019-12-05

2595 Dopamine modulates the size of striatal projection neuron ensembles

Maltese, M.; March, J. R.; Bashaw, A. G.; Tritsch, N. X.

10.1101/865006 — neuroscience — Posted on 2019-12-05

2596 LARGE MICROBIOTA SURVEY REVEALS HOW THE MICROBIAL ECOLOGY OF COOKED HAM IS SHAPED BY DIFFERENT PROCESSING STEPS

Zagdoun, M.; Coeuret, G.; N'Dione, M.; Champomier Verges, M. C.; Chaillou, S.

10.1101/865857 — microbiology — Posted on 2019-12-05

2597 DrivAER: Identification of driving transcriptional programs in single-cell RNA sequencing data

Simon, L. M.; Yan, F.; Zhao, Z.

10.1101/864165 — bioinformatics — Posted on 2019-12-05

2598 RePAIR: a power solution to animal experimentation

Bonapersona, V.; Hoijtink, H.; RELACS, ; Sarabdjitsingh, R. A.; Joels, M.

10.1101/864652 — animal behavior and cognition — Posted on 2019-12-05

2599 On deleterious mutations in perennials: inbreeding depression, mutation load and life-history evolution

Lesaffre, T.; Billiard, S.

10.1101/865220 — evolutionary biology — Posted on 2019-12-05

2600 Agonist-selective recruitment of engineered protein probes and of GRK2 by opioid receptors in living cells

Stoeber, M.; Jullie, D.; Li, J.; Chakraborty, S.; Majumdar, S.; Lambert, N. A.; Manglik, A.; von Zastrow, M.

10.1101/866780 — cell biology — Posted on 2019-12-05

2601 Rootstock choice can dramatically affect grapevine growth

Migicovsky, Z.; Cousins, P.; Jordan, L. M.; Myles, S.; Striegler, R. K.; Verdegaal, P.; Chitwood, D. H.

10.1101/864850 — plant biology — Posted on 2019-12-05

2602 ERP sources in middle cingulate and precuneus differentiate Parkinson's patients from healthy controls and lingual gyri sources reflect human recombinant EPO effects in a Flanker task

Bringas Vega, M. L.; Liu, S.; Zhang, M.; Pedroso Ibanez, I.; Morales Chacon, L. M.; Galan Garcia, L.; Perez Bocourt, V.; Jahanshahi, M.; Valdes-Sosa, P. A.

10.1101/864397 — neuroscience — Posted on 2019-12-05

2603 Enhanced post-traumatic headache-like behaviors and diminished contribution of peripheral CGRP in female rats following a mild closed head injury

Bree, D.; Mackenzie, K.; Stratton, J.; Levy, D.

10.1101/865444 — neuroscience — Posted on 2019-12-05

2604 NK cells negatively regulate CD8 T cells to promote immune exhaustion and chronic Toxoplasma gondii infection

Gigley, J. P.; Ivanova, D. L.; Krempels, R.; Denton, S. L.; Fettel, K. D.; Saltz, G. M.; Rach, D.; Fatima, R.; Mundhenke, T.; Materi, J.; Dunay, I. R.

10.1101/864272 — immunology — Posted on 2019-12-05

2605 Golgi outposts locally regulate microtubule orientation in neurons but are not required for the overall polarity of the dendritic cytoskeleton

Yang, S. Z.; Wildonger, J.

10.1101/866574 — cell biology — Posted on 2019-12-05

2606 Antagonism in Evolutionary Opportunities Results in Non-Monotonic Evolution Across an Environmental Gradient

Behringer, M. G.; Ho, W.-C.; Miller, S. F.; Meraz, J. C.; Boyer, G. F.; Lynch, M.

10.1101/865584 — evolutionary biology — Posted on 2019-12-05

2607 Competition between kinesin-1 and myosin-V define Drosophila posterior determination

Lu, W.; Lakonishok, M.; Liu, R.; Billington, N.; Rich, A.; Glotzer, M.; Sellers, J. R.; Gelfand, V. I.

10.1101/866467 — cell biology — Posted on 2019-12-05

2608 Tracking selective rehearsal and active inhibition of memory traces in directed forgetting

Fellner, M.-C.; Waldhauser, G. T.; Axmacher, N.

10.1101/864819 — neuroscience — Posted on 2019-12-05

2609 Deficiency of Norepinephrine Transmission In Brain Contributed To Seizure-Induced Respiratory Arrest In the DBA/1 Mouse SUDEP Model

Shen, Y.; MA, H.; Lu, H.; Zhao, H.; Sun, J.; Cheng, Y.; Shen, Y.; Zhou, Y. D.; Zhang, H.

10.1101/865691 — neuroscience — Posted on 2019-12-05

2610 Bipartite functional fractionation within the default network supports disparate forms of internally oriented cognition

Chiou, R.; Humphreys, G.; Lambon Ralph, M.

10.1101/864603 — neuroscience — Posted on 2019-12-05

2611 Chemogenetic actuator drugs impair prefrontal cortex-dependent working memory in rhesus monkeys

Upright, N. A.; Baxter, M. G.

10.1101/864140 — neuroscience — Posted on 2019-12-05

2612 An updated antennal lobe atlas for the yellow fever mosquito Aedes aegypti

Shankar, S.; McMeniman, C. J.

10.1101/865675 — neuroscience — Posted on 2019-12-05

2613 Altered motoneuron properties contribute to motor deficits in a rabbit hypoxia ischemia model of cerebral palsy

Steele, P. R.; Cavarsan, C. F.; Dowaliby, L.; Westefeld, M.; Drobyshevsky, A.; Gorassini, M. A.; Quinlan, K. A.

10.1101/817957 — neuroscience — Posted on 2019-12-05

2614 Confluence of timing and reward biases in perceptual decision-making dynamics

Shinn, M.; Ehrlich, D.; Lee, D.; Murray, J. D.; Seo, H.

10.1101/865501 — neuroscience — Posted on 2019-12-05

2615 Neurobehavioral Correlates of How Time-on-task and Sleep Deprivation Modulate Deployment of Cognitive Effort

Massar, S. A. A.; Lim, J.; Sasmita, K.; Raghunath, B. L.; Chee, M. W. L.

10.1101/865766 — neuroscience — Posted on 2019-12-05

2616 Combining antibiotics with antivirulence compounds is effective and can reverse selection for antibiotic resistance in Pseudomonas aeruginosa

Rezzoagli, C.; Archetti, M.; Baumgartner, M.; Kuemmerli, R.

10.1101/861799 — microbiology — Posted on 2019-12-05

2617 Moxifloxacin efficacy against Mycobacterium abscessus in vivo using zebrafish model

Nie, W.; Gao, S.; Teng, T.; Zhou, W.; Shang, Y.; Jing, W.; Shi, W.; Wang, Q.; Huang, X.; Cai, B.; Wang, J.; Wang, J.; Guo, R.; Ge, Q.; Nie, L.; Han, X.; Du, Y.; Chu, N.

10.1101/865824 — microbiology — Posted on 2019-12-05

2618 Phylogeographic evidence that the distribution of cryptic euryhaline species in the Gambusia punctata species group in Cuba was shaped by the archipelago geological history

Garcia-Machado, E.; Ponce de Leon, J. L.; Gutierrez-Costa, M. A.; Michel-Salzat, A.; Germon, I.; Casane, D.

10.1101/865469 — evolutionary biology — Posted on 2019-12-05

2619 Marine water environmental DNA metabarcoding provides a comprehensive fish diversity assessment and reveals spatial patterns in a large oceanic area

Fraija-Fernandez, N.; Bouquieaux, M.-C.; Rey, A.; Mendibil, I.; Cotano, U.; Irigoien, X.; Santos, M.; Rodriguez-Ezpeleta, N.

10.1101/864710 — ecology — Posted on 2019-12-05

2620 Are "early birds" bolder? Early daily activity is not correlated with risk-taking behaviour in a major invasive species

Sbragaglia, V.; Breithaupt, T.

10.1101/864611 — animal behavior and cognition — Posted on 2019-12-05

2621 Simultaneous MRI-EEG during a motor imagery neurofeedback task: an open access brain imaging dataset for multi-modal data integration.

Lioi, G.; Cury, C.; Perronnet, L.; Mano, M.; Bannier, E.; Lecuyer, A.; Barillot, C.

10.1101/862375 — neuroscience — Posted on 2019-12-05

2622 The demyelinating agent cuprizone induces a male-specific reduction in binge eating in the binge-prone C57BL/6NJ strain

Babbs, R. K.; Beierle, J. A.; Kelliher, J. C.; Medeiros, A. R.; Anandakumar, J.; Shah, A.; Yao, E. J.; Chen, M. M.; Bryant, C. D.

10.1101/865600 — neuroscience — Posted on 2019-12-05

2623 Relationships between landscape structure and the prevalence of two tick-borne infectious agents, Anaplasma phagocytophilum and Borrelia burgdorferi sensu lato, in small mammal communities

Perez, G.; Bastian, S.; Chastagner, A.; Agoulon, A.; Rantier, Y.; Vourc'h, G.; Plantard, O.; Butet, A.

10.1101/718403 — ecology — Posted on 2019-12-05

2624 The effect of flow on swimming bacteria controls the initial colonization of curved surfaces

Secchi, E.; Vitale, A.; Mino, G. L.; Kantsler, V.; Eberl, L.; Rusconi, R.; Stocker, R.

10.1101/866491 — biophysics — Posted on 2019-12-05

2625 Topographic Signatures of Global Object Perception in Human Visual Cortex

Stoll, S.; Finlayson, N. J.; Schwarzkopf, D. S.

10.1101/864736 — neuroscience — Posted on 2019-12-05

2626 Transcription factor motifs in anterior insula gene-expression in mood disorder

Jabbi, M.; Arasappan, D.; Eickhoff, S. B.; Hofmann, H.

10.1101/864900 — genomics — Posted on 2019-12-05

2627 Bacteria contribute to plant secondary compound degradation in a generalist herbivore system

Francoeur, C. B.; Khadempour, L.; Moreira-Soto, R. D.; Gotting, K.; Book, A. J.; Pinto-Tomas, A. A.; Keefover-Ring, K.; Currie, C. R.

10.1101/865212 — ecology — Posted on 2019-12-05

2628 Interdependent regulation of stereotyped and stochastic photoreceptor fates in the fly eye

Miller, A. C.; Urban, E.; Lyons, E. L.; Herman, T. G.; Johnston, R. J.

10.1101/865717 — developmental biology — Posted on 2019-12-05

2629 Material aging causes centrosome weakening and disassembly during mitotic exit

Mittasch, M.; Tran, V. M.; Rios, M. U.; Fritsch, A. W.; Enos, S. J.; Ferreira Gomes, B.; Bond, A.; Kreysing, M.; Woodruff, J. B.

10.1101/866434 — cell biology — Posted on 2019-12-05

2630 3dSpAn: an interactive software for 3D segmentation and analysis of dendritic spines

Basu, S.; Das, N.; Baczynska, E.; Bijata, M.; Zeug, A.; Plewczynski, D.; Saha, P. K.; Ponimaskin, E.; Wlodarczyk, J.

10.1101/864587 — neuroscience — Posted on 2019-12-05

2631 A Distinct Contractile Injection System Found in a Majority of Adult Human Microbiomes

Rojas, M. I.; Cavalcanti, G. S.; McNair, K.; Benler, S.; Alker, A. T.; Cobian-Guemes, A. G.; Giluso, M.; Levi, K.; Rohwer, F.; Beyhan, S.; Edwards, R.; Shikuma, N. J.

10.1101/865204 — microbiology — Posted on 2019-12-05

2632 Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex

Casanova, J. E.; D'Souza, R. S.; Lim, J. Y.; Servage, K.; Zhang, J.; Orth, K.; Sosale, N.; Lazzara, M.; Allegood, J.

10.1101/866392 — cell biology — Posted on 2019-12-05

2633 Deep learning enables structured illumination microscopy with low light levels and enhanced speed

Jin, L.; Liu, B.; Zhao, F.; Hahn, S.; Dong, B.; Song, R.; Elston, T. C.; Xu, Y.; Hahn, K. M.

10.1101/866822 — biophysics — Posted on 2019-12-05

2634 Cortical state transitions and stimulus response evolve along stiff and sloppy parameter dimensions, respectively

Ponce-Alvarez, A.; Mochol, G.; Hermoso-Mendizabal, A.; de la Rocha, J.; Deco, G.

10.1101/839365 — neuroscience — Posted on 2019-12-05

2635 Automatic annotation of Cryo-EM maps with the convolutional neural network Haruspex

Mostosi, P.; Schindelin, H.; Kollmannsberger, P.; Thorn, A.

10.1101/644476 — molecular biology — Posted on 2019-12-05

2636 Genomics of sorghum local adaptation to a parasitic plant

Bellis, E. S.; Kelly, E. A.; Lorts, C. M.; Gao, H.; Deleo, V. L.; Rouhan, G.; Budden, A.; Bhaskara, G. B.; Hu, Z.; Muscarella, R.; Timko, M. P.; Nebie, B.; Runo, S. M.; Chilcoat, N. D.; Juenger, T. E.; Morris, G.; dePamphilis, C. W.; Lasky, J.

10.1101/633529 — evolutionary biology — Posted on 2019-12-05

2637 Targeting dual signaling pathways in concert with immune checkpoints for the treatment of pancreatic cancer

Knudsen, E.; Kumarasamy, V.; Chung, S.; Vail, P.; Tzetzo, S.; Ruiz, A.; Seshadri, M.; Abrams, S.; Wang, J.; Witkiewicz, A.

10.1101/860247 — cancer biology — Posted on 2019-12-05

2638 Co-transcriptional folding of a bio-orthogonal fluorescent scaffolded RNA origami

Torelli, E.; Kozyra, J. W.; Shirt-Ediss, B.; Piantanida, L.; Voïtchovsky, K.; Krasnogor, N.

10.1101/864678 — synthetic biology — Posted on 2019-12-05

2639 In Vivo Emergence of a Novel Protease Inhibitor Resistance Signature in HIV-1 Matrix

Datir, R. P.; Kemp, S.; El Bouzidi, K.; Mlcochova, P.; Goldstein, R. A.; Breuer, J.; Towers, G. J.; Jolly, C.; Quinones-Mateu, M. E.; Dakum, P. S.; Ndembi, N.; Gupta, R. K.

10.1101/865840 — microbiology — Posted on 2019-12-05

Mesas, A.; Jaramillo, A.; Castaneda, L. E.

10.1101/864793 — evolutionary biology — Posted on 2019-12-05

2641 Hidden dynamic signatures drive substrate selectivity in the disordered phosphoproteome

Cho, M. H.; Wrabl, J. O.; Taylor, J.; Hilser, V. J.

10.1101/866558 — biophysics — Posted on 2019-12-05

2642 Cluster Analysis Based on Fasting and Postprandial Plasma Glucose and Insulin Concentrations

Altuve, M. A.; Severeyn, E.

10.1101/861468 — bioengineering — Posted on 2019-12-05

2643 MrDNA: A multi-resolution model for predicting the structure and dynamics of nanoscale DNA objects

Maffeo, C.; Aksimentiev, A.

10.1101/865733 — synthetic biology — Posted on 2019-12-05

2644 Combining machine learning and a universal acoustic feature-set yields efficient automated monitoring of ecosystems

Sethi, S. S.; Jones, N. S.; Fulcher, B. D.; Picinali, L.; Clink, D. J.; Klinck, H.; Orme, C. D. L.; Wrege, P. H.; Ewers, R. M.

10.1101/865980 — ecology — Posted on 2019-12-05

2645 Combining high-resolution AFM with MD simulations shows that DNA supercoiling induces kinks and defects that enhance flexibility and recognition.

Pyne, A. L. B.; Noy, A.; Main, K.; Velasco-Berrelleza, V.; Piperakis, M. M.; Mitchenhall, L. A.; Cugliandolo, F. M.; Beton, J. G.; Stevenson, C. E. M.; Hoogenboom, B. W.; Bates, A. D.; Maxwell, A.; Harris, S. A.

10.1101/863423 — biophysics — Posted on 2019-12-05

2646 Comparing current noise in biological and solid-state nanopores

Fragasso, A.; Schmid, S.; Dekker, C.

10.1101/866384 — biophysics — Posted on 2019-12-05

2647 Inferring translational heterogeneity from ribosome profiling data

do Couto Bordignon, P.; Pechmann, S.

10.1101/866582 — bioinformatics — Posted on 2019-12-05

2648 The Trk fused gene-product (Tfg) is part of a 600-700kDa CARMA1 complex

Grohmann, M.; Steinmetz, T.; Jaeck, H.-M.; Mielenz, D.

10.1101/857342 — biochemistry — Posted on 2019-12-05

2649 The Role of Sensory Uncertainty in Simple Contour Integration

Zhou, Y.; Acerbi, L.; Ma, W. J.

10.1101/350082 — neuroscience — Posted on 2019-12-05

2650 Massively parallel discovery of human-specific substitutions that alter neurodevelopmental enhancer activity

Uebbing, S.; Gockley, J.; Reilly, S. K.; Kocher, A. A.; Geller, E.; Gandotra, N.; Scharfe, C.; Cotney, J.; Noonan, J. P.

10.1101/865519 — genomics — Posted on 2019-12-05

2651 Characterization of conformational dynamics at microsecond timescale in the RNA-binding regions of dsRNA-binding domains

Paithankar, H.; Chugh, J.

10.1101/797449 — biophysics — Posted on 2019-12-05

2652 Effects of feeding treatment on growth rate and performance of primiparous Holstein dairy heifers

Le Cozler, Y.; Jurquet, J.; Bedere, N.

10.1101/760082 — zoology — Posted on 2019-12-05

2653 Genomics of Human Respiratory Syncytial Virus Vaccine Attenuation

Junier, T.; Kaiser, L.; Chaturvedi, N.; Fellay, J.

10.1101/862185 — genomics — Posted on 2019-12-05

2654 A machine learning based approach to the segmentation of micro CT data in archaeological and evolutionary sciences

O'Mahoney, T.; McKnight, L.; Lowe, T.; Mednikova, M.; Dunn, J.

10.1101/859983 — evolutionary biology — Posted on 2019-12-05

2655 Pegasus, a small extracellular peptide regulating the short-range diffusion of Wingless

Magny, E. G.; Pueyo Marques, J. I.; Bishop, S. A.; Aguilar-Hidalgo, D.; Couso, J. P.

10.1101/807701 — developmental biology — Posted on 2019-12-05

2656 Chloroplast cold-resistance is mediated by the acidic domain of the RNA binding protein CP31A

Okuzaki, A.; Lehniger, M.-K.; Muino, J.; Lenzen, B.; Ruehle, T.; Leister, D.; Ohler, U.; Schmitz-Linneweber, C.

10.1101/832337 — plant biology — Posted on 2019-12-05

2657 A new lineage of segmented RNA viruses infecting animals

Obbard, D. J.; Shi, M.; Roberts, K. E.; Longdon, B. E.; Dennis, A. B.

10.1101/741645 — evolutionary biology — Posted on 2019-12-05

2658 Local axonal conduction delays underlie precise timing of a neural sequence

Egger, R.; Tupikov, Y.; Katlowitz, K. A.; Benezra, S. E.; Picardo, M. A.; Moll, F.; Kornfeld, J.; Jin, D. Z.; Long, M. A.

10.1101/864231 — neuroscience — Posted on 2019-12-05

2659 Trans-acting role of the leader peptide peTrpL in posttranscriptional regulation of multiresistance

Melior, H.; Li, S.; Förstner, K. U.; Azarderakhsh, S.; Barth-Weber, S.; Evguenieva-Hackenberg, E.

10.1101/864512 — molecular biology — Posted on 2019-12-05

2660 Automatic annotation of Cryo-EM maps with the convolutional neural network Haruspex

Mostosi, P.; Schindelin, H.; Kollmannsberger, P.; Thorn, A.

10.1101/644476 — molecular biology — Posted on 2019-12-05

2661 Metagenomic shotgun analyses reveal complex patterns of intra- and interspecific variation in the intestinal microbiomes of codfishes

Riiser, E. S.; Haverkamp, T. H. A.; Varadharajan, S.; Borgan, O.; Jakobsen, K. S.; Jentoft, S.; Star, B.

10.1101/864439 — microbiology — Posted on 2019-12-05

2662 The rodent vaginal microbiome across the estrous cycle and the effect of genital nerve electrical stimulation

Levy, M.; Bassis, C. M.; Kennedy, E.; Yoest, K. E.; Becker, J. B.; Bell, J.; Berger, M. B.; Bruns, T. M.

10.1101/647545 — microbiology — Posted on 2019-12-05

2663 Glial cell mechanosensitivity is reversed by adhesion cues

Tomba, C.; Migdal, C.; Fuard, D.; Villard, C.; Nicolas, A.

10.1101/865303 — biophysics — Posted on 2019-12-05

2664 Single-cell mass-spectrometry quantifies the emergence of macrophage heterogeneity

Specht, H.; Emmott, E.; Petelski, A.; Huffman, R. G.; Perlman, D. H.; Serra, M.; Kharchenko, P.; Koller, A.; Slavov, N.

10.1101/665307 — bioengineering — Posted on 2019-12-05

2665 Antibiograms and Molecular Characterization of Drug Resistance of Mycobacterium abscessus complex from Patients with Multidrug-Resistant Pulmonary Tuberculosis (MDR TB) Infection

Bongulto, K. A.; Ang, C. F.; Cabrera, E. C.

10.1101/864447 — microbiology — Posted on 2019-12-05

2666 The nucleus acts as a ruler tailoring cell responses to spatial constraints

Lomakin, A.; Cattin, C.; Cuvelier, D.; Alraies, Z.; Molina, M.; Nader, G.; Srivastava, N.; Garcia Arcos, J.-M.; Zhitnyak, I.; Bhargava, A.; Driscoll, M. K.; Welf, E. S.; Fiolka, R. P.; Petrie, R.; Manel, N.; Lennon-Dumenil, A.-M. P.; Muller, D.; Piel, M.

10.1101/863514 — cell biology — Posted on 2019-12-05

2667 Regulatory asymmetry in the negative single-input module network motif: Role of network size, growth rate and binding affinity

Ali, M. Z.; Parisutham, V.; Chuobey, S.; Brewster, R. C.

10.1101/865527 — systems biology — Posted on 2019-12-05

2668 An unsupervised feature extraction and selection strategy for identifying epithelial-mesenchymal transition state metrics in breast cancer and melanoma

Klinke, D. J.; Torang, A.

10.1101/865139 — cancer biology — Posted on 2019-12-05

2669 Clair: Exploring the limit of using a deep neural network on pileup data for germline variant calling

Luo, R.; Wong, C.-L.; Wong, Y.-S.; Tang, C.-I.; Liu, C.-M.; Leung, H. C. M.; Lam, T.-W.

10.1101/865782 — bioinformatics — Posted on 2019-12-05

2670 Conceptual models of entrainment, jet-lag, and seasonality

Tokuda, I. T.; Schmal, C.; Ananthasubramaniam, B. T.; Herzel, H.

10.1101/865592 — systems biology — Posted on 2019-12-05

2671 The nucleus measures shape deformation for cellular proprioception and regulates adaptive morphodynamics

Venturini, V.; Pezzano, F.; Catala Castro, F.; Häkkinen, H.-M.; Jimenez-Delgado, S.; Colomer-Rosell, M.; Marro Sanchez, M.; Tolosa-Ramon, Q.; Paz-Lopez, S.; Valverde, M. A.; Loza-Alvarez, P.; Krieg, M.; Wieser, S.; Ruprecht, V.

10.1101/865949 — cell biology — Posted on 2019-12-05

2672 Determination of secretory granule maturation times in pancreatic islet beta-cells by serial block face scanning electron microscopy

Rao, A.; McBride, E. L.; Zhang, G.; Cai, T.; Notkins, A. L.; Aronova, M. A.; Leapman, R. D.

10.1101/865683 — biophysics — Posted on 2019-12-05

2673 Sensing Traction Force on Matrix Induces Cell-Cell Distant Mechanical Communications for Self-assembly

Ouyang, M.; Qian, Z.; Bu, B.; Jin, Y.; Wang, J.; Liu, L.; Pan, Y.; Deng, L.

10.1101/866228 — biophysics — Posted on 2019-12-05

2674 Identification of a functional small non-coding RNA encoded by African swine fever virus

Dunn, L. E. M.; Ivens, A.; Netherton, C. L.; Beard, P. M.

10.1101/865147 — molecular biology — Posted on 2019-12-05

2675 Parallel siRNA screens to identify kinase and phosphatase modulators of NF-κB activity following DNA damage

Sfikas, A.; Banks, P.; Su, L.-I.; Schlossmacher, G.; Perkins, N. D.; Yemm, A. I.

10.1101/866061 — cell biology — Posted on 2019-12-05

2676 Investigating the Role of Hypoxia-Induced Migration in Glioblastoma Growth Rates

Curtin, L.; Hawkins Daarud, A.; van der Zee, K. G.; Swanson, K. R.; Owen, M. R.

10.1101/862920 — cancer biology — Posted on 2019-12-05

2677 Epiviz File Server: Query, Transform and Interactively Explore Data from Indexed Genomic Files

Kancherla, J.; Yang, Y.; Chae, H.; Bravo, H. C.

10.1101/865295 — bioinformatics — Posted on 2019-12-05

2678 scOpen: chromatin-accessibility estimation of single-cell ATAC data

Li, Z.; Kuppe, C.; Cheng, M.; Menzel, S.; Zenke, M.; Kramann, R.; Costa, I. G.

10.1101/865931 — bioinformatics — Posted on 2019-12-05

2679 Cultivation of Exoelectrogenic Bacteria in Conductive DNA Nanocomposite Hydrogels Yields a Programmable Biohybrid Materials System

Hu, Y.; Rehnlund, D.; Klein, E.; Gescher, J.; Niemeyer, C. M.

10.1101/864967 — biochemistry — Posted on 2019-12-05

2680 Efficient Homology-directed Repair with Circular ssDNA Donors

Iyer, S.; Mir, A.; Ibraheim, R.; Lee, J.; VegaBadillo, J.; Roscoe, B.; Zhu, L. J.; Liu, P.; Luk, K.; Mintzer, E.; de Brito, J. S.; Zamore, P.; Sontheimer, E. J.; Wolfe, S.

10.1101/864199 — molecular biology — Posted on 2019-12-05

2681 Nanometric axial localization of single fluorescent molecules with modulated excitation

Jouchet, P.; Cabriel, C.; Bourg, N.; Bardou, M.; Pous, C.; FORT, E.; LEVEQUE-FORT, S.

10.1101/865865 — biophysics — Posted on 2019-12-05

2682 The smfBox: an open-source platform for single-molecule FRET

Ambrose, B.; Baxter, J.; Cully, J.; Willmott, M.; Steele, E.; Bateman, B. C.; Martin-Fernandez, M. L.; Cadby, A.; Shewring, J.; Aaldering, M.; Craggs, T. D.

10.1101/861922 — biophysics — Posted on 2019-12-05

2683 Evolution of multifunctionality through a pleiotropic substitution in the innate immune protein S100A9

Harman, J. L.; Loes, A. N.; Warren, G. D.; Heaphy, M. C.; Lampi, K. J.; Harms, M. J.

10.1101/865493 — biochemistry — Posted on 2019-12-05

2684 Increased yields of duplex sequencing data by a series of quality control tools

Povysil, G.; Heinzl, M.; Salazar, R.; Stoler, N.; Nekrutenko, A.; Tiemann-Boege, I.

10.1101/864835 — genomics — Posted on 2019-12-05

2685 Sporadic activation of an oxidative stress-dependent NRF2-p53 signaling network in breast epithelial spheroids and premalignancies

Pereira, E. J.; Burns, J. S.; Lee, C. Y.; Marohl, T.; Calderon, D.; Wang, L.; Atkins, K. A.; Wang, C.-C.; Janes, K.

10.1101/862474 — cancer biology — Posted on 2019-12-05

2686 A deep learning-based model of normal histology

Sing, T.; Hoefling, H.; Hossain, I.; Boisclair, J.; Doelemeyer, A.; Flandre, T.; Piaia, A.; Romanet, V.; Santarossa, G.; Saravanan, C.; Sutter, E.; Turner, O.; Wuersch, K.; Moulin, P.

10.1101/838417 — pathology — Posted on 2019-12-05

2687 Recent selection of candidate genes for mammal domestication in Europeans and language change in Europe: a hypothesis

Benitez-Burraco, A.; Chekalin, E.; Bruskin, S.; Morozova, I.

10.1101/684621 — evolutionary biology — Posted on 2019-12-05

2688 Long-read-based Human Genomic Structural Variation Detection with cuteSV

Jiang, T.; Liu, B.; Jiang, Y.; Li, J.; Gao, Y.; Cui, Z.; Liu, Y.; Wang, Y.

10.1101/780700 — bioinformatics — Posted on 2019-12-05

2689 Evaluation of Model Fit of Inferred Admixture Proportions

Garcia-Erill, G.; Albrechtsen, A.

10.1101/708883 — bioinformatics — Posted on 2019-12-05

2690 Addressing dereplication crisis: Taxonomy-free reduction of massive genome collections using embeddings of protein content

Viehweger, A.; Hölzer, M.; Brandt, C.

10.1101/855262 — bioinformatics — Posted on 2019-12-05

2691 Dynamically Linking Influenza Virus Infection with Lung Injury to Predict Disease Severity

Myers, M. A.; Smith, A. P.; Lane, L. C.; Moquin, D. J.; Vogel, P.; Woolard, S.; Smith, A. M.

10.1101/555276 — systems biology — Posted on 2019-12-05

2692 The hourglass organization of the Caenorhabditis elegans connectome

Sabrin, K.; Wei, Y.; van den Heuvel, M.; Dovrolis, C.

10.1101/600999 — neuroscience — Posted on 2019-12-05

2693 Barcoding and demultiplexing Oxford Nanopore native RNA sequencing reads with deep residual learning

Smith, M. A.; Ersavas, T.; Ferguson, J. M.; Liu, H.; Lucas, M. C.; Begik, O.; Bojarski, L.; Barton, K.; Novoa, E. M.

10.1101/864322 — genomics — Posted on 2019-12-05

2694 Integrated analyses of early responses to radiation in glioblastoma identify new alterations in RNA processing and candidate target genes to improve treatment outcomes

Choudhary, S.; Burns, S. C.; Mirsafian, H.; Li, W.; Vo, D. T.; Qiao, M.; Smith, A. D.; Penalva, L. O.

10.1101/863852 — cancer biology — Posted on 2019-12-05

2695 Computation-guided optimization of split protein systems

Dolberg, T. B.; Meger, A. T.; Boucher, J. D.; Corcoran, W. K.; Schauer, E. E.; Prybutok, A. N.; Raman, S.; Leonard, J. N.

10.1101/863530 — synthetic biology — Posted on 2019-12-05

2696 α2δ-2 protein controls structure and function at the cerebellar climbing fiber synapse

Beeson, K. A.; Beeson, R.; Westbrook, G. L.; Schnell, E.

10.1101/685818 — neuroscience — Posted on 2019-12-05

2697 Single-cell RNA-seq reveals CD16- monocytes as key regulators of human monocyte transcriptional response to Toxoplasma

Patir, A. A.; Gossner, A.; Ramachandran, P.; Alves, J.; Freeman, T.; Henderson, N. C.; Watson, M.; Hassan, M. A.

10.1101/863274 — genomics — Posted on 2019-12-05

2698 Rapid diagnosis of SCA36 in a three-generation family using short-read whole genome sequencing data

Rafehi, H.; Szmulewicz, D. J.; Pope, K.; Wallis, M.; Christodoulou, J.; White, S. M.; Delatycki, M.; Lockhart, P. J.; Bahlo, M.

10.1101/851675 — genomics — Posted on 2019-12-05

2699 perfectphyloR: An R package for reconstructing perfect phylogenies

Karunarathna, C. B.; Graham, J.

10.1101/674523 — genetics — Posted on 2019-12-05

2700 A tradeoff between tolerance and resistance to a major fungal pathogen in elite wheat cultivars

Mikaberidze, A.; McDonald, B. A.

10.1101/354357 — ecology — Posted on 2019-12-05

2701 The Chlamydia type III effector TarP alters the dynamics and organization of host cell focal adhesions

Pedrosa, A. T.; Murphy, K.; Nogueira, A. T.; Brinkworth, A.; Thwaites, T. R.; Aaron, J.; Chew, T.-L.; CARABEO, R.

10.1101/250563 — cell biology — Posted on 2019-12-05

2702 Multiscale mechanical model for cell division orientation in developing biological systems

Leggio, B.; Laussu, J.; Faure, E.; Lemaire, P.; Godin, C.

10.1101/785337 — biophysics — Posted on 2019-12-05

2703 Kia kaua te reo e rite ki te moa, ka ngaro: Do not let the language suffer the same fate as the moa

Barrett-Walker, T.; Plank, M. J.; Ka'ai-Mahuta, R.; Hikuroa, D.; James, A.

10.1101/817148 — ecology — Posted on 2019-12-05

2704 A sparse EEG-informed fMRI model for hybrid EEG-fMRI neurofeedback prediction

Cury, C.; Maurel, P.; Gribonval, R.; Barillot, C.

10.1101/599589 — neuroscience — Posted on 2019-12-05

2705 Dynamic brain network changes in resting-state reflect neuroplasticity: molecular and cognitive evidence

Liu, Z.; Xiao, X.; Zhang, K.; Zhao, Q.; Cao, X.; Li, C.; Wang, M.; Lin, W.; Qiu, J.; Sahakian, B. J.; Feng, J.; Robbins, T. W.; Zhang, J.

10.1101/695122 — neuroscience — Posted on 2019-12-05

2706 Color tuning of face-selective neurons in macaque inferior temporal cortex

Duyck, M.; Gruen, T.; Tello, L.; Eastman, S.; Fuller-Deets, J.; Conway, B.

10.1101/863779 — neuroscience — Posted on 2019-12-05

2707 Nanopore long reads enable the first complete genome assembly of a Malaysian Vibrio parahaemolyticus isolate bearing the pVa plasmid associated with acute hepatopancreatic necrosis disease

Gan, H. M.; Austin, C. M.

10.1101/861476 — genomics — Posted on 2019-12-05

2708 Inferring the landscape of recombination using recurrent neural networks

Adrion, J. R.; Galloway, J. G.; Kern, A. D.

10.1101/662247 — evolutionary biology — Posted on 2019-12-05

2709 Trophic cascade driven by behavioural fine-tuning as naive prey rapidly adjust to a novel predator

Jolly, C. J.; Smart, A. S.; Moreen, J.; Webb, J. K.; Gillespie, G. R.; Phillips, B. L.

10.1101/856997 — ecology — Posted on 2019-12-05

2710 Differential Allele-Specific Expression Uncovers Breast Cancer Genes Dysregulated By Cis Noncoding Mutations

Przytycki, P. F.; Singh, M.

10.1101/675462 — bioinformatics — Posted on 2019-12-05

2711 Modelling the influence of the hippocampal memory system on the oculomotor system.

Ryan, J. D.; Shen, K.; Kacollja, A.; Tian, H.; Griffiths, J.; Bezgin, G.; McIntosh, R.

10.1101/303511 — neuroscience — Posted on 2019-12-05

2712 Concurrent EEG- and fMRI-derived functional connectomes exhibit linked dynamics

Wirsich, J.; Giraud, A.-L.; Sadaghiani, S.

10.1101/464438 — neuroscience — Posted on 2019-12-05

2713 A semi-supervised approach for cell phenotypic and functional estimation in tissue microenvironment

Chang, W.; Wan, C.; Zhang, Y.; So, K.; Richardson, B.; Sun, Y.; Zhang, X.; Huang, K.; Zhang, A.; Lu, X.; Cao, S.; Zhang, C.

10.1101/426593 — bioinformatics — Posted on 2019-12-05

2714 Mechanisms of colistin resistance in Escherichia strains isolated from bloodstream infections

Janssen, A. B.; Bartholomew, T. L.; Marciszewska, N. P.; Bonten, M.; Willems, R. J. L.; Bengoechea, J. A.; Schaik, W.

10.1101/864983 — microbiology — Posted on 2019-12-05

2715 Characterization of the impact of daclizumab beta on circulating natural killer cells by mass cytometry

Ranganath, T.; Simpson, L. J.; Seiler, C.; Ferreira, A.-M.; Vendrame, E.; Zhao, N. Q.; Fontenot, J. D.; Holmes, S. P.; Blish, C. A.

10.1101/865477 — immunology — Posted on 2019-12-05

2716 Massively parallel discovery of human-specific substitutions that alter neurodevelopmental enhancer activity

Uebbing, S.; Gockley, J.; Reilly, S. K.; Kocher, A. A.; Geller, E.; Gandotra, N.; Scharfe, C.; Cotney, J.; Noonan, J. P.

10.1101/865519 — genomics — Posted on 2019-12-05

2717 Apparent size and morphology of bacterial microcompartments varies with technique

Kennedy, N. W.; Hershewe, J. M.; Nichols, T. M.; Roth, E. W.; Wilke, C. D.; Jewett, M. C.; Tullman-Ercek, D.

10.1101/864074 — synthetic biology — Posted on 2019-12-05

2718 Dynamic competition for hexon binding between core protein VII and lytic protein VI promotes adenovirus maturation and entry

Hernando-Perez, M.; Martin-Gonzalez, N.; Perez-Illana, M.; Suomalainen, M.; Ostapchuk, P.; Condezo, G. N.; Menendez, M.; Greber, U. F.; Hearing, P.; de Pablo, P. J.; San Martin, C.

10.1101/857581 — microbiology — Posted on 2019-12-05

2719 BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity

Bittner, Z. A.; Liu, X.; Dickhoefer, S.; Kalbacher, H.; Bosch, K.; Andreeva, L.; Marcu, A.; Stevanovic, S.; Mangan, M.; Duewell, P.; Lovotti, M.; Herster, F.; Loeffler, M. W.; Shankar, S.; Tapia-Abellan, A.; Wolz, O. O.; Shilling, N. A.; Kuemmerle-Deschner, J.; Wagner, S.; Delor, A.; Grimbacher, B.; Wu, H.; Latz, E.; Weber, A. N.

10.1101/864702 — immunology — Posted on 2019-12-05

2720 Increased yields of duplex sequencing data by a series of quality control tools

Povysil, G.; Heinzl, M.; Salazar, R.; Stoler, N.; Nekrutenko, A.; Tiemann-Boege, I.

10.1101/864835 — genomics — Posted on 2019-12-05

2721 Osteoblast-osteoclast co-culture amplifies inhibitory effects of FG-4592 on osteoclast formation and reduces bone resorption activity

Hulley, P. A.; Papadimitriou-Olivgeri, I.; Knowles, H. J.

10.1101/863498 — cell biology — Posted on 2019-12-05

2722 COMUNET: a tool to explore and visualize intercellular communication

Solovey, M.; Scialdone, A.

10.1101/864686 — bioinformatics — Posted on 2019-12-05

2723 A yeast platform for high-level synthesis of natural and unnatural tetrahydroisoquinoline alkaloids

Pyne, M. E.; Kevvai, K.; Grewal, P. S.; Narcross, L.; Choi, B.; Bourgeois, L.; Dueber, J. E.; Martin, V. J.

10.1101/863506 — synthetic biology — Posted on 2019-12-05

2724 Genomics of local adaptation in blue tit

Perrier, C.; Rougemont, Q.; Charmantier, A.

10.1101/864975 — evolutionary biology — Posted on 2019-12-05

2725 Excess Centrosomes Disrupt Vascular Lumenization and Endothelial Cell Adherens Junctions

Berlin, D. M.; Kushner, E. J.; Davis, K. L.; Bautch, V. L.

10.1101/863787 — cell biology — Posted on 2019-12-05

2726 Bipartite Tight Spectral Clustering (BiTSC) Algorithm for Identifying Conserved Gene Co-clusters in Two Species

Sun, Y.; Zhou, H.; Li, J. J.

10.1101/865378 — bioinformatics — Posted on 2019-12-05

2727 Direct RNA sequencing reveals m6A modifications on adenovirus RNA are necessary for efficient splicing

Price, A. M.; Hayer, K. E.; McIntyre, A. B. R.; Gokhale, N. S.; Della Fera, A. N.; Mason, C. E.; Horner, S. M.; Wilson, A. C.; Depledge, D. P.; Weitzman, M. D.

10.1101/865485 — molecular biology — Posted on 2019-12-05

2728 PIM Kinases Alter Mitochondrial Dynamics and Chemosensitivity in Lung Cancer

Chauhan, S. S.; Toth, R. K.; Jensen, C. C.; Casillas, A. L.; Kashatus, D. S.; Warfel, N. A.

10.1101/863811 — cancer biology — Posted on 2019-12-05

2729 Model for disordered proteins with strongly sequence-dependent liquid phase behavior

Statt, A.; Casademunt, H.; Brangwynne, C. P.; Panagiotopoulos, A. Z.

10.1101/864942 — biophysics — Posted on 2019-12-05

2730 Profiling and structural analysis of cardenolides in two species of Digitalis using liquid chromatography coupled with high-resolution mass spectrometry

Ravi, B. G.; Guardian, M. G. E.; Dickman, R.; Wang, Z. Q.

10.1101/864959 — biochemistry — Posted on 2019-12-05

2731 MicroRNA miR-100 decreases glioblastoma growth by targeting SMARCA5 and ErbB3 in tumor-initiating cells

Alrfaei, B. M.; Vemuganti, R.; Kuo, J. S.

10.1101/865105 — molecular biology — Posted on 2019-12-04

2732 Evolution of populations with strategy-dependent time delays

Miekisz, J.; Bodnar, M.

10.1101/865071 — evolutionary biology — Posted on 2019-12-04

2733 Room without a view - den construction in relation to body size in brown bears.

Shiratsuru, S.; Friebe, A.; Swenson, J. E.; Zedrosser, A.

10.1101/865188 — ecology — Posted on 2019-12-04

2734 Accurate Prediction of Kinase-Substrate Networks Using Knowledge Graphs

Novacek, V.; McGauran, G.; Matallanas, D.; Vallejo Blanco, A.; Conca, P.; Munoz, E.; Costabello, L.; Kanakaraj, K.; Nawaz, Z.; Mohamed, S. K.; Vandenbussche, P.-Y.; Ryan, C.; kolch, W.; Fey, D.

10.1101/865055 — bioinformatics — Posted on 2019-12-04

2735 Role of nitric oxide in improving seed germination and alleviation of copper-induced photosynthetic inhibition in Indian mustard

Rather, B. A.; Mir, I. R.; Masood, A.; Anjum, N. A.; Khan, N. A.

10.1101/865162 — plant biology — Posted on 2019-12-04

2736 Prolonged inflammation leads to ongoing damage after spinal cord injury.

Kwiecien, J. M.; Dabrowski, W.; Dabrowska-Bouta, B.; Sulkowski, G.; Oakden, W.; Kwiecien-Delaney, C. J.; Yaron, J. R.; Zhang, L.; Schutz, L.; Marzec-Kotarska, B.; Stanisz, G. J.; Karis, J. P.; Struzynska, L.; Lucas, A. R.

10.1101/865089 — pathology — Posted on 2019-12-04

2737 Estimating the impact of pneumococcal conjugate vaccines on childhood pneumonia in sub-Saharan Africa: A systematic review.

Onwuchekwa, C.; Edem, B.; Williams, V.; oga, E.

10.1101/865154 — pathology — Posted on 2019-12-04

2738 Comprehensive identification of HSP70/HSC70 Chaperone Clients in Human Cells

Ryu, S. W.; Stewart, R.; Pectol, C.; Ender, N.; Wimalarathne, O.; Lee, J.-H.; Zanini, C.; Harvey, A.; Huibregtse, J.; Mueller, P.; Paull, T.

10.1101/865030 — molecular biology — Posted on 2019-12-04

2739 Cost implications of a nationwide survey of schistosomiasis and other intestinal helminthiases in Sudan

Elhag, M. S.; Jin, Y.; Amin, M. A.; Ismail, H. A. H. A.; Hong, S.-T.; Jang, H.; Doh, Y.-A.; Cha, S.

10.1101/865113 — microbiology — Posted on 2019-12-04

2740 Why the tumor cell metabolism is not that abnormal

Jacquet, P.; Stephanou, A.

10.1101/865048 — cell biology — Posted on 2019-12-04

2741 Understanding the genetic risks of complex diseases using the additive epistatic interaction model: a simulation study

Wang, Y.

10.1101/865196 — bioinformatics — Posted on 2019-12-04

2742 Systems biology informed deep learning for inferring parameters and hidden dynamics

Yazdani, A.; Raissi, M.; Karniadakis, G. E.

10.1101/865063 — bioinformatics — Posted on 2019-12-04

2743 Experience and relatedness influence mating interactions in a simultaneously hermaphroditic snail, Physa gyrina

McCarthy, T.

10.1101/865170 — animal behavior and cognition — Posted on 2019-12-04

2744 Highly clustered de novo frameshift variants in the neuronal splicing factor NOVA2 result in a specific abnormal C terminal part and cause a severe form of intellectual disability with autistic features.

Mattioli, F.; Hayot, G.; Drouot, N.; Isidor, B.; Courraud, J.; Tran Mau Them, F.; Sellier, C.; Hinckelman, M.-V.; Goldman, A.; Telegrafi, A.; Boughton, A.; Gamble, C.; Moutton, S.; Quartier, A.; Jean, N.; Vanness, P.; Grotto, S.; Nambot, S.; Douglas, G.; Si, Y. C.; Chelly, J.; Shad, Z.; Kaplan, E.; Dineen, R.; Golzio, C.; Charlet, N.; Mandel, J.-L.; Piton, A.

10.1101/858696 — genetics — Posted on 2019-12-04

2745 Color tuning of face-selective neurons in cells in macaque inferior temporal cortex

Duyck, M.; Gruen, T.; Tello, L.; Eastman, S.; Fuller-Deets, J.; Conway, B.

10.1101/863779 — neuroscience — Posted on 2019-12-04

2746 Surfactin production is not essential for pellicle and root-associated biofilm development of Bacillus subtilis

Therien, M.; Kiesewalter, H. T.; Auria, E.; Charron-Lamoureux, V.; Wibowo, M.; Maroti, G.; Kovacs, A. T.; Beauregard, P. B.

10.1101/865345 — microbiology — Posted on 2019-12-04

2747 End-to-end multitask learning, from protein language to protein features without alignments

Elnaggar, A.; Heinzinger, M.; Dallago, C.; Rost, B.

10.1101/864405 — bioinformatics — Posted on 2019-12-04

2748 Genomic Analysis of Powdery Mildew Resistance in a Hop (Humulus lupulus L.) Bi-parental Population Segregating for R6-locus

Padgitt-Cobb, L. K.; Kingan, S. B.; Henning, J. A.

10.1101/864249 — genomics — Posted on 2019-12-04

2749 Single-cell RNA-seq reveals CD16- monocytes as key regulators of human monocyte transcriptional response to Toxoplasma

Patir, A. A.; Gossner, A.; Ramachandran, P.; Freeman, T.; Henderson, N. C.; Watson, M.; Hassan, M. A.

10.1101/863274 — genomics — Posted on 2019-12-04

2750 A complex IRES at the 5'-UTR of a viral mRNA assembles a functional 48S complex via an uAUG intermediate.

Neupane, R.; Pisareva, V.; Rodriguez, C.; Pisarev, A.; Fernandez, I.

10.1101/863761 — biochemistry — Posted on 2019-12-04

2751 Attraction, Dynamics, and Phase Transitions in Fire Ant Tower-Building

Nave, G. K.; Mitchell, N. T.; Chan Dick, J. A.; Schuessler, T.; Lagarrigue, J. A.; Peleg, O.

10.1101/864306 — systems biology — Posted on 2019-12-04

2752 Measurement of Prostate Volume with MRI (A Guide for the Perplexed): Biproximate Method with Analysis of Precision and Accuracy

Wasserman, N. F.; Niendorf, E.; Spilseth, B.

10.1101/856542 — pathology — Posted on 2019-12-04

2753 Barcoding and demultiplexing Oxford Nanopore native RNA sequencing reads with deep residual learning

Smith, M. A.; Ferguson, J. M.; Ersavas, T.; Liu, H.; Lucas, M. C.; Begik, O.; Bojarski, L.; Barton, K.; Novoa, E. M.

10.1101/864322 — genomics — Posted on 2019-12-04

2754 N-acetyltransferase 2 genotypes amongst ulu Speaking South Africans and isoniazid / N-acetyl-isoniazid pharmacokinetics during ant-tuberculosis treatment

Mthiyane, T.; Millard, J.; Adamson, J.; Balakrishna, Y.; Connolly, C.; Owen, A.; Rustomjee, R.; Dheda, K.; McIlleron, H.; Pym, A. S.

10.1101/864454 — genetics — Posted on 2019-12-04

2755 Optogenetic control of PRC1 reveals its role in kinetochore alignment at the metaphase plate

Jagric, M.; Risteski, P.; Martincic, J.; Milas, A.; Tolic, I. M.

10.1101/865394 — cell biology — Posted on 2019-12-04

2756 Measurement and models accounting for cell death capture hidden variation in compound response

Bae, S. Y.; Guan, N.; Yan, R.; Warner, K.; Meyer, A. S.

10.1101/863597 — cancer biology — Posted on 2019-12-04

2757 Comparing the prioritisation of items and feature-dimensions in visual working memory

Hajonides, J. E.; van Ede, F.; Stokes, M. G.; Nobre, A. C.

10.1101/863191 — neuroscience — Posted on 2019-12-04

2758 The trade-offs of sharing pollinators: pollination service is determined by the community context

Cagua, E. F.; Marrero, H. J.; Tylianakis, J. M.; Stouffer, D. B.

10.1101/865279 — ecology — Posted on 2019-12-04

2759 Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures

de March, C. A.; Titlow, W. B.; Sengoku, T.; Breheny, P.; Matsunami, H.; McClintock, T. S.

10.1101/865386 — cell biology — Posted on 2019-12-04

2760 Twinfilin uncaps filament barbed ends to promote turnover of lamellipodial actin networks

Hakala, M.; Wioland, H.; Tolonen, M.; Jegou, A.; Romet-Lemonne, G.; Lappalainen, P.

10.1101/864769 — cell biology — Posted on 2019-12-04

2761 The significance of microRNA genes expression in ovarian cancer cell lines resistant to cytotoxic drugs

Kazmierczak, D.; Jopek, K.; Sterzynska, K.; Rucinski, M.; Januchowski, R.

10.1101/859264 — cancer biology — Posted on 2019-12-04

2762 Loss of Aurora kinase signaling allows lung cancer cells to adopt an alternative cell cycle and resist anti-mitotic drugs

Roth, M. G.; Tagal, V.

10.1101/865337 — cancer biology — Posted on 2019-12-04

2763 WEDGE: recovery of gene expression values for sparse single-cell RNA-seq datasets using matrix decomposition

Hu, Y.; Li, B.; Liu, N.; Cai, P.; Chen, F.; Qu, K.

10.1101/864488 — bioinformatics — Posted on 2019-12-04

2764 Pay to know me in your eyes: A computational account and oxytocin modulation of social evaluation

Wang, D.; Ma, Y.

10.1101/864330 — neuroscience — Posted on 2019-12-04

2765 Reduced axonal caliber and white matter changes in a rat model of Fragile X syndrome with a deletion of a K Homology domain of Fmr1.

Golden, C. E.; Yee, Y.; Wang, V. X.; Harony-Nicolas, H.; Hof, P. R.; Lerch, J. P.; Buxbaum, J. D.

10.1101/864371 — neuroscience — Posted on 2019-12-04

2766 Mice preferentially use increases in cerebral cortex spike rates to detect changes in visual stimuli

Cone, J. J.; Bade, M. L.; Masse, N. Y.; Page, E. A.; Freedman, D. J.; Maunsell, J. H.

10.1101/865410 — neuroscience — Posted on 2019-12-04

2767 Persistence of anti-zika virus Immunoglobulin M antibodies in children with microcephaly up to four years after primary infection

Soares Campos, G.; Hughes Carvalho, R.; Teixeira, M. G.; Britto e Silva, G. F.; de Araujo Rolo, C.; Dorea Luz Menezes, A.; Ribeiro Mota Souza, R.; Sardi, S. I.

10.1101/857847 — immunology — Posted on 2019-12-04

2768 EpitoCore: mining conserved epitope vaccine candidates in the core proteome of multiple bacteria strains

Fiuza, T. S.; Lima, J. P. M.; de Souza, G. A.

10.1101/864264 — bioinformatics — Posted on 2019-12-04

2769 Computation-guided optimization of split protein systems

Dolberg, T. B.; Meger, A. T.; Boucher, J. D.; Corcoran, W. K.; Schauer, E. E.; Prybutok, A. N.; Raman, S. N.; Leonard, J. N.

10.1101/863530 — synthetic biology — Posted on 2019-12-04

2770 Structural Brain Alterations and Their Association with Cognitive Function and Symptoms in Attention-Deficit/Hyperactivity Disorder Families

Jiang, W.; Duan, K.; Rootes-Murdy, K.; Hoekstra, P. J.; Hartman, C.; Oosterlaan, J.; Heslenfeld, D.; Franke, B.; Buitelaar, J.; Arias-Vasquez, A.; Liu, J.; Turner, J.

10.1101/863605 — neuroscience — Posted on 2019-12-04

2771 Role of post-trial visual feedback on unintentional force drift during isometric finger force production tasks

S, B.; Rachaveti, D.; SKM, V.

10.1101/864413 — neuroscience — Posted on 2019-12-04

2772 Spatial, climate, and ploidy factors drive genomic diversity and resilience in the widespread grass Themeda triandra

Ahrens, C. W.; James, E.; Miller, A. D.; Aitken, N. C.; Borevitz, J. O.; Cantrill, D.; Rymer, P. D.

10.1101/864298 — genomics — Posted on 2019-12-04

2773 Bacterial Genome wide association studies (bGWAS) and transcriptomics identifies cryptic antimicrobial resistance mechanisms in Acinetobacter baumannii

Roe, C.; Williamson, C. H.; Vazquez, A. J.; Kyger, K.; Valentine, M.; Bowers, J. R.; Phillips, P. D.; Harrison, V.; Driebe, E.; Engelthaler, D. M.; Sahl, J. W.

10.1101/864462 — genomics — Posted on 2019-12-04

2774 Variation of bacterial communities along the vertical gradient in Lake Issyk Kul, Kyrgyzstan

Rojas-Jimenez, K.; Araya-Lobo, A.; Quesada-Perez, F.; Akerman-Sanchez, J.; Delgado-Duran, B.; Ganzert, L.; Zavialov, P. O.; Alymkulov, S.; Kirillin, G.; Grossart, H. P.

10.1101/864355 — ecology — Posted on 2019-12-04

2775 LIPID ANCHORING OF ARCHAEOSORTASE SUBSTRATES AND MID-CELL GROWTH IN HALOARCHAEA

Abdul-Halim, M. F.; Schulze, S.; DiLucido, A.; Pfeiffer, F.; Bisson Filho, A. W.; Pohlschroder, M.

10.1101/863746 — cell biology — Posted on 2019-12-04

2776 Ecological causes of speciation and species richness in the mammal tree of life

Upham, N. S.; Esselstyn, J. A.; Jetz, W.

10.1101/504803 — evolutionary biology — Posted on 2019-12-04

2777 Modulation of T helper 1 and T helper 2 immune balance in a stress mouse model during Chlamydia muridarum genital infection

BELAY, T.; Martin, E.; Brown, G.; Crenshaw, R.; Street, J.; Freeman, A.; Musick, S.; Kinder, T.

10.1101/863753 — microbiology — Posted on 2019-12-04

2778 Genomic investigation of the strawberry pathogen Phytophthora fragariae indicates pathogenicity is associated with transcriptional variation in three key races

Adams, T. M.; Armitage, A. D.; Sobczyk, M. K.; Bates, H. J.; Tabima, J. F.; Kronmiller, B. A.; Tyler, B. M.; Grunwald, N. J.; Dunwell, J. M.; Nellist, C. F.; Harrison, R. J.

10.1101/860619 — genomics — Posted on 2019-12-04

2779 Optimization and quantitative evaluation of fluorescence in situ hybridization chain reaction in clarified fresh-frozen brain tissues

KUMAR, V.; KROLEWSKI, D. M.; HEBDA-BAUER, E. K.; PARSEGIAN, A.; MARTIN, B.; FOLTZ, M.; AKIL, H.; WATSON, S.

10.1101/763920 — neuroscience — Posted on 2019-12-04

2780 Multi-timescale hybrid components of the functional brain connectome: A bimodal EEG-fMRI decomposition

Wirsich, J.; Amico, E.; Giraud, A.-L.; Goni, J.; Sadaghiani, S.

10.1101/800797 — neuroscience — Posted on 2019-12-04

2781 SCRIBE: a new approach to dropout imputation and batch effects correction for single-cell RNA-seq data

Zhang, Y.; Liang, K.; Liu, M.; Li, Y.; Ge, H.; Zhao, H.

10.1101/793463 — bioinformatics — Posted on 2019-12-04

2782 Regulatory T cell expansion by a highly CD25-dependent IL-2 mutein arrests ongoing autoimmunity

Khoryati, L.; Pham, M. N.; Sherve, M.; Kumari, S.; Cook, K.; Pearson, J.; Bogdani, M.; Campbell, D. J.; Gavin, M. A.

10.1101/862789 — immunology — Posted on 2019-12-04

2783 Rampant loss of social traits during domestication of a Bacillus subtilis natural isolate

Barreto, H. C.; Cordeiro, T. N.; Henriques, A. O.; Gordo, I.

10.1101/751438 — evolutionary biology — Posted on 2019-12-04

2784 MB-GAN: Microbiome Simulation via Generative Adversarial Network

Rong, R.; Jiang, S.; Xu, L.; Xiao, G.; Xie, Y.; Liu, D. J.; Li, Q.; Zhan, X.

10.1101/863977 — bioinformatics — Posted on 2019-12-04

2785 A new method of Bayesian causal inference in non-stationary environments

Shinohara, S.; Manome, N.; Suzuki, K.; Chung, U.-i.; Takahashi, T.; Okamoto, H.; Gunji, Y.; Nakajima, Y.; Mitsuyoshi, S.

10.1101/861096 — animal behavior and cognition — Posted on 2019-12-04

2786 MicroRNA function transitions from regulating developmental genes to transposable elements during the maturation of pollen

Oliver, C.; Annacondia, M. L.; Wang, Z.; Slotkin, R. K.; Kohler, C.; Martinez, G.

10.1101/864017 — plant biology — Posted on 2019-12-04

2787 Mental travel in the social domain

Hayman, M.; Arzy, S.

10.1101/849497 — neuroscience — Posted on 2019-12-04

2788 Estimating genetic inheritance in case-control studies

Li, N.; Zhu, J.; Li, Z.; Li, Q.

10.1101/847269 — genetics — Posted on 2019-12-04

2789 Processing of the SARS-CoV pp1a/ab nsp7-10 region

Krichel, B.; Falke, S.; Hilgenfeld, R.; Redecke, L.; Uetrecht, C.

10.1101/860049 — biophysics — Posted on 2019-12-04

2790 Volumetric Segmentation and Characterisation of the Paracingulate Sulcus on MRI Scans

Yang, J.; Wang, D.; Rollins, C.; Leming, M.; Lio, P.; Suckling, J.; Murray, G. K.; Garrison, J. R.; Cachia, A.

10.1101/859496 — bioinformatics — Posted on 2019-12-04

2791 Identification of evolutionarily conserved nuclear matrix proteins and their prokaryotic origins

Sureka, R.; Mishra, R. K.

10.1101/863969 — molecular biology — Posted on 2019-12-04

2792 Within-host Mycobacterium tuberculosis evolution: a population genetics perspective

Morales-Arce, A. Y.; Harris, R. B.; Stone, A. C.; Jensen, J. D.

10.1101/863894 — genetics — Posted on 2019-12-04

2793 Structural instability and divergence from conserved residues underlie intracellular retention of mammalian odorant receptors

Ikegami, K.; de March, C. A.; Nagai, M.; Ghosh, S.; Do, M.; Sharma, R.; Bruguera, E.; Lu, Y.; Fukutani, Y.; Vaidehi, N.; Yohda, M.; Matsunami, H.

10.1101/605337 — cell biology — Posted on 2019-12-04

2794 HeALTH: An Automated Platform for Long-term Longitudinal Studies of Whole Organisms under Precise Environmental Control

Le, K. N.; Zhan, M.; Cho, Y.; Wan, J.; Patel, D. S.; Lu, H.

10.1101/863985 — animal behavior and cognition — Posted on 2019-12-04

2795 A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila

Port, F.; Strein, C.; Stricker, M.; Rauscher, B.; Heigwer, F.; Zhou, J.; Beyersdorffer, C.; Frei, J.; Hess, A.; Kern, K.; Malamud, R.; Pavlovic, B.; Radecke, K.; Schmitt, L.; Voos, L.; Valentini, E.; Boutros, M.

10.1101/636076 — genetics — Posted on 2019-12-04

2796 Enhanced inference of ecological networks by parameterizing ensembles of population dynamics models constrained with prior knowledge

Liao, C.; Xavier, J.; Zhu, Z.

10.1101/686402 — ecology — Posted on 2019-12-04

2797 Tyrosine-based Signals Regulate the assembly of Daple-PARD3 Complex at Cell-cell Junctions during Polarized Planar Cell Migration

Ear, J.; Saklecha, A.; Rajapakse, N.; Choi, J.; Ghassemian, M.; Kufareva, I.; Ghosh, P.

10.1101/717041 — cell biology — Posted on 2019-12-04

2798 Relationships and genome evolution of polyploid Salix species revealed by RAD sequencing data

Wagner, N. D.; He, L.; Hoerandl, E.

10.1101/864504 — evolutionary biology — Posted on 2019-12-04

2799 Summer drought decreases the predictability of local extinctions in a butterfly metapopulation

van Bergen, E.; Dallas, T.; DiLeo, M. F.; Kahilainen, A.; Mattila, A. L. K.; Luoto, M.; Saastamoinen, M.

10.1101/863795 — ecology — Posted on 2019-12-04

2800 Klf9 is a key feedforward regulator of the transcriptomic response to glucocorticoid receptor activity

Gans, I.; Hartig, E. I.; Zhu, S.; Tilden, A. R.; Hutchins, L.; Maki, N.; Graber, J. H.; Coffman, J. A.

10.1101/863555 — developmental biology — Posted on 2019-12-04

2801 Slo2 potassium channel function depends on a SCYL1 protein

Niu, L.-G.; Liu, P.; Wang, Z.-W.; Chen, B.

10.1101/864645 — neuroscience — Posted on 2019-12-04

2802 Deep exploration networks for rapid engineering of functional DNA sequences

Linder, J.; Bogard, N.; Rosenberg, A.; Seelig, G.

10.1101/864363 — genomics — Posted on 2019-12-04

2803 Disorder and interfaces in proteins are two sides of the same coin

Seoane, B.; Carbone, A.

10.1101/863571 — bioinformatics — Posted on 2019-12-04

2804 Interrogating mechanisms of ssDNA binding to a viral HUH-endonuclease by alanine scanning of an electrostatic patch

Nelson, A.; Tompkins, K.; Ramirez, M. P.; Gordon, W. R.

10.1101/861070 — biochemistry — Posted on 2019-12-04

2805 Mutation of an L-Type Calcium Channel Gene Leads to a Novel Human Primary Cellular Immunodeficiency

Fenninger, F.; Stanwood, S. R.; Lu, C.-J.; Pfeifer, C. G.; Khan, O.; Romberg, N. D.; Herati, R.; Wherry, E. J.; O'Boyle, K. C.; Henrickson, S. E.; Maurer, K.; Ruffner, M. A.; Jefferies, W. A.; Sullivan, K. E.

10.1101/864280 — immunology — Posted on 2019-12-04

2806 Integrated analyses of early responses to radiation in glioblastoma identify new alterations in RNA processing and candidate target genes to improve treatment outcomes

Choudhary, S.; Burns, S. C.; Mirsafian, H.; Li, W.; Vo, D. T.; Qiao, M.; Smith, A. D.; Penalva, L. O.

10.1101/863852 — cancer biology — Posted on 2019-12-04

2807 Polynuclear ruthenium amines inhibit K2P channels via a 'finger in the dam' mechanism

Pope, L.; Lolicato, M.; Minor, D. L.

10.1101/863837 — biophysics — Posted on 2019-12-04

2808 Quantifying the heterogeneity of macromolecular machines by mass photometry

Sonn Segev, A.; Belacic, K.; Bodrug, T.; Young, G.; VanderLinden, R. T.; Schulman, B.; Schimpf, J.; Friedrich, T.; Vinh Dip, P.; Schwartz, T.; Bauer, B.; Peters, J.-M.; Struwe, W. B.; Benesch, J. L.; Brown, N. G.; Haselbach, D.; Kukura, P.

10.1101/864553 — biophysics — Posted on 2019-12-04

2809 DomainScope: A Disease Network based on protein domain connections

Voskanian-kordi, A.; Funai, A.; Kann, M.

10.1101/862870 — bioinformatics — Posted on 2019-12-04

2810 A Machine Learning Approach for Long-Term Prognosis of Bladder Cancer based on Clinical and Molecular Features

Song, Q.; Seigne, J.; Schned, A.; Kelsey, K.; Karagas, M.; Hassanpour, S.

10.1101/557470 — bioinformatics — Posted on 2019-12-04

2811 The absence of C-5 DNA methylation in Leishmania donovani allows DNA enrichment from complex samples

Cuypers, B.; Dumetz, F.; Meysman, P.; Laukens, K.; De Muylder, G.; Dujardin, J.-C.; Domagalska, M. A.

10.1101/747063 — molecular biology — Posted on 2019-12-04

2812 Genome-wide analysis of chalcone synthase (CHS) family from eggplant (Solanum melongena L.) in flavonoid biosynthetic pathway and expression pattern in response to heat stress

Wu, X.; Zhang, S.; Liu, X.; Shang, J.; Zhu, A.; Zhu, Z.; Zha, D.

10.1101/863696 — genomics — Posted on 2019-12-03

2813 NCBP2 modulates neurodevelopmental defects of the 3q29 deletion in Drosophila and X. laevis models

Singh, M. D.; Jensen, M.; Lasser, M.; Huber, E.; Yusuff, T.; Pizzo, L.; Lifschutz, B.; Desai, I.; Kubina, A.; Yennawar, S.; Kim, S.; Iyer, J.; Rincon-Limas, D. E.; Lowery, L. A.; Girirajan, S.

10.1101/614750 — genomics — Posted on 2019-12-04

2814 Role of protein dynamics in enthalpy-driven recognition of topologically distinct dsRNAs by dsRBDs

Paithankar, H.; Chugh, J.

10.1101/862326 — biophysics — Posted on 2019-12-04

2815 Evaluating the data quality of iNaturalist termite records

Hochmair, H.; Scheffrahn, R.; Basille, M.; Boone, M.

10.1101/863688 — zoology — Posted on 2019-12-03

2816 Testosterone Changes in Female Pandas in Estrus

Liu, X.; Yuan, L.; Wang, W.; You, Y.; Liu, Y.; Ma, T.; Wang, Z.; Jin, X.; Ma, Q.; Lu, Y.; Zhang, J.; Zhao, S.

10.1101/863704 — zoology — Posted on 2019-12-03

2817 Condition dependent strategies of egg size variation in the Common Eider Somateria mollissima

Christensen, T. K.; Balsby, T. J. S.

10.1101/863654 — zoology — Posted on 2019-12-03

2818 Acute inflammatory events attenuate high-sucrose diet-induced neurodegenerative processes in reproductively normal female wild-type mice

Pacholko, A. G.; Bekar, L. K.

10.1101/863670 — neuroscience — Posted on 2019-12-03

2819 Hypoxia on vhl-deficient cells to obtain hif related genes through bioinformatics analysis.

Lin, H.; Liu, H.

10.1101/863662 — cell biology — Posted on 2019-12-03

2820 Involvement in family planning service utilization and associated factors among married men at Debre Tabor Town Northwest, Ethiopia, 2017

Demissie, T. W.; Nigatu, A. M.; Tegnge, E. M.

10.1101/863712 — scientific communication and education — Posted on 2019-12-03

2821 Host targets of effectors of the lettuce downy mildew Bremia lactucae from cDNA-based yeast two-hybrid screening

Pelgrom, A. J. E.; Meisrimler, C.-N.; Elberse, J.; Koorman, T.; Boxem, M.; Van den Ackerveken, G.

10.1101/863738 — plant biology — Posted on 2019-12-03

2822 Individual differences in the mechanistic control of the dopaminergic midbrain

Hellrung, L.; Kirschner, M.; Sulzer, J.; Sladky, R.; Scharnowski, F.; Herdener, M.; Tobler, P. N.

10.1101/863639 — neuroscience — Posted on 2019-12-03

2823 Novel ankyrin-repeat mutant and modifiers of a kafirin mutant improve sorghum protein digestibility

Diatta-Holgate, E.; Tuinstra, M. R.; Addo-Quaye, C.; Cisse, N.; Danquah, A.; Tongoona, P.; Danquah, E.; Weil, C. F.

10.1101/863951 — plant biology — Posted on 2019-12-03

2824 Reliable method for high quality His-tagged and untagged E. coli phosphoribosyl phosphate synthase (Prs) purification

Walter, B. M.; Szulc, A.; Glinkowska, M. K.

10.1101/864173 — molecular biology — Posted on 2019-12-03

2825 Counteracting resistance to targeted therapy in melanoma by inhibiting discoidin domain receptors

Sala, M.; Allain, N.; Henriet, E.; Uguen, A.; Di-Tommaso, S.; Dupuy, J.-W.; Gerard, E.; Dugot-Senant, N.; Rousseau, B.; Merlio, J.-P.; Pham-Ledart, A.; Vergier, B.; Moreau, V.; Saltel, F.; Raymond, A.-A.

10.1101/857904 — cancer biology — Posted on 2019-12-03

2826 Functional role of Polymerase IV during pollen development in Capsella

Wang, Z.; Butel, N.; Santos-Gonzalez, J.; Borges, F.; Yi, J.; Martienssen, R. A.; Martinez, G.; Kohler, C.

10.1101/863522 — plant biology — Posted on 2019-12-03

2827 Maternal Obesity and Western-style Diet Impair Fetal and Juvenile Offspring Skeletal Muscle Insulin-Stimulated Glucose Transport in Nonhuman Primates

Campodonico-Burnett, W.; Hetrick, B.; Wesolowski, S. R.; Schenk, S.; Takahashi, D. L.; Dean, T. A.; Sullivan, E. L.; Kievit, P.; Gannon, M.; Aagaard-Tillery, K.; Friedman, J. E.; McCurdy, C. E.

10.1101/864082 — physiology — Posted on 2019-12-03

2828 Ex vivo and in vivo imaging of mouse parietal association cortex activity in episodes of cued fear memory formation and retrieval

Ivashkina, O. I.; Gruzdeva, A. M.; Roshchina, M. A.; Toropova, K. A.; Anokhin, K. V.

10.1101/863589 — neuroscience — Posted on 2019-12-03

2829 Cell shape changes during larval body plan development in Clytia hemisphaerica

Kraus, Y.; Chevalier, S.; Houliston, E.

10.1101/864223 — developmental biology — Posted on 2019-12-03

2830 Efficient Detection and Classification of Epigenomic Changes Under Multiple Conditions

Baldoni, P. L.; Rashid, N. U.; Ibrahim, J. G.

10.1101/864124 — bioinformatics — Posted on 2019-12-03

2831 Long vs short-term synaptic learning rules after optogenetic spike-timing-dependent plasticity

Anisimova, M.; van Bommel, B.; Wiegert, J. S.; Mikhaylova, M.; Oertner, T. G.; Gee, C. E.

10.1101/863365 — neuroscience — Posted on 2019-12-03

2832 Characterizing the tolerance of phage therapy candidate OMKO1 to environmental stress

Blazanin, M.; Lam, W. T.; Turner, P.

10.1101/864025 — microbiology — Posted on 2019-12-03

2833 Direct therapeutic targeting of SWI/SNF induces epigenetic reprogramming and durable tumor regression in rhabdoid tumor

Chasse, M. H.; Johnson, B. K.; Boguslawski, E. A.; Sorensen, K. M.; Heo, L.; Madaj, Z. B.; Beddows, I.; Foxa, G. E.; Kitchen-Goosen, S. M.; Williams, B. O.; Triche, T. J.; Grohar, P. J.

10.1101/861484 — cancer biology — Posted on 2019-12-03

2834 LEARNING AND INTERPRETING THE GENE REGULATORY GRAMMAR IN A DEEP LEARNING FRAMEWORK

Capra, J. A.; Chen, L.

10.1101/864058 — bioinformatics — Posted on 2019-12-03

2835 Transformer neural network for protein specific de novo drug generation as machine translation problem

Grechishnikova, D. A.

10.1101/863415 — bioinformatics — Posted on 2019-12-03

2836 Late life metformin treatment limits cell survival and shortens lifespan by triggering an aging-associated failure of energy metabolism.

Espada, L.; Dakhovnik, A.; Chaudhari, P. S.; Martirosyan, A.; Miek, L.; Poliezhaieva, T.; Schaub, Y.; Nair, A.; Doering, N.; Rahnis, N.; Werz, O.; Koeberle, A.; Kirkpatrick, J.; Ori, A.; Ermolaeva, M.

10.1101/863357 — physiology — Posted on 2019-12-03

2837 Extracting the GEMs: Genotype, Environment and Microbiome interactions shaping host phenotypes

Oyserman, B. O.; Cordovez, V.; Flores, S. W. S.; Nijveen, H.; Medema, M. H.; Raaijmakers, J. M.

10.1101/863399 — microbiology — Posted on 2019-12-03

2838 Genetic dominance governs the evolution and spread of mobile genetic elements in bacteria

Rodriguez-Beltran, J.; Sorum, V.; Toll-Riera, M.; de la Vega, C.; Pena-Miller, R.; San Millan, A.

10.1101/863472 — microbiology — Posted on 2019-12-03

2839 The apparent requirement for protein synthesis during G2 phase is due to checkpoint activation

Lockhead, S.; Moskaleva, A.; Kamenz, J.; Chen, Y.; Kang, M.; Reddy, A. R. K.; Santos, S.; Ferrell, J. E.

10.1101/863548 — cell biology — Posted on 2019-12-03

2840 Simulation of cryo-EM ensembles from atomic models of molecules exhibiting continuous conformations

Seitz, E.; Acosta-Reyes, F.; Schwander, P.; Frank, J.

10.1101/864116 — biophysics — Posted on 2019-12-03

2841 Experience dependent contextual codes in the hippocampus

Plitt, M. H.; Giocomo, L. M.

10.1101/864090 — neuroscience — Posted on 2019-12-03

2842 CD4+ T cells persist for years in the human small intestine and mediate robust Th1 immunity.

Bartolome Casado, R.; Landsverk, O. J. B.; Kumar Chauhan, S.; Saetre, F.; Hagen, K. T.; Yaqub, S.; Oyen, O.; Horneland, R.; Aandahl, E. M.; Aabakken, L.; Baekkevold, E. S.; Jahnsen, F. L.

10.1101/863407 — immunology — Posted on 2019-12-03

2843 Mitotic spindle elongation is driven by joint microtubule sliding action of kinesins KIF4A and EG5

Vukusic, K.; Buđa, R.; Ponjavic, I.; Risteski, P.; Tolic, I. M.

10.1101/863381 — cell biology — Posted on 2019-12-03

2844 Mining Archive.org's Twitter Stream Grab for Pharmacovigilance Research Gold

Tekumalla, R.; Asl, J. R.; Banda, J. M.

10.1101/859611 — bioinformatics — Posted on 2019-12-03

2845 ApproXON: Heuristic Approximation to the E-Field-Threshold for Deep Brain Stimulation Volume-of-Tissue-Activated Estimation

Proverbio, D.; Husch, A. D.

10.1101/863613 — neuroscience — Posted on 2019-12-03

2846 Sex and gene flow modulate evolution during rangeexpansions in the protist Tetrahymena thermophila

Moerman, F.; Fronhofer, E. A.; Wagner, A.; Altermatt, F.

10.1101/863340 — evolutionary biology — Posted on 2019-12-03

2847 Multiscale criticality measures as general-purpose gauges of proper brain function

Fekete, T.; Hinrichs, H.; Sitt, J.; Heinze, H.-J.; Shriki, O.

10.1101/863431 — neuroscience — Posted on 2019-12-03

2848 Plant Small RNA Species Direct Gene Silencing in Pathogenic Bacteria as well as Disease Protection

SINGLA-RASTOGI, M.; CHARVIN, M.; Thiebeauld, O.; Perez-Quintero, A. L.; RAVET, A.; EMIDIO-FORTUNATO, A.; MENDU, V.; NAVARRO, L.

10.1101/863902 — plant biology — Posted on 2019-12-03

2849 Uncharacteristic task-evoked pupillary responses implicate atypical locus coeruleus activity in autism

Granovetter, M. C.; Burlingham, C. S.; Blauch, N. M.; Minshew, N. J.; Heeger, D. J.; Behrmann, M.

10.1101/863928 — neuroscience — Posted on 2019-12-03

2850 NON-EQUILIBRIUM BELOUSOV-ZHABOTINSKY REACTION DESCRIBES THE SPONTANEOUS ACTIVITY OF THE BRAIN

Zhang, Y.; Guo, S.; Sun, M.; Tozzi, A.; Zhao, X.

10.1101/863324 — neuroscience — Posted on 2019-12-03

2851 Resolving intrinsic ambiguities of the fMRI signal in the human brain

Liu, E. Y.; Haist, F.; Shin, D. D.; Buxton, R. B.

10.1101/833681 — neuroscience — Posted on 2019-12-03

2852 Detection of extended-spectrum beta-lactamase (ESBL) genes and plasmid replicons in Enterobacteriaceae using PlasmidSPAdes assembly of short-read sequence data

Stohr, J. J. J. M.; Kluytmans-van den Bergh, M. F. Q.; Wedema, R.; Friedrich, A. W.; Kluytmans, J. A. J. W.; Rossen, J. W. A.

10.1101/863316 — microbiology — Posted on 2019-12-03

2853 Bacteriophages inhibit biofilms formed by multi-drug resistant bacteria isolated from septic wounds

Rani, P. R.; Lakshmi, D. V.; VIJAYA RAGHAVA PRAASAD, V. D.

10.1101/863076 — microbiology — Posted on 2019-12-03

2854 The amplification of genetic factors for early vocabulary during children's language and literacy development

Verhoef, E.; Shapland, C. Y.; Fisher, S. E.; Dale, P. S.; St Pourcain, B.

10.1101/863118 — genetics — Posted on 2019-12-03

2855 Genome resequencing, improvement of variant calling, and population genomic analyses provide insights into the seedlessness in the genus Vitis

Kim, M.-S.; Hur, Y. Y.; Kim, J. H.; Jeong, S.-C.

10.1101/863233 — genetics — Posted on 2019-12-03

2856 Systemic Brain Tumor Delivery of Synthetic Protein Nanoparticles for Glioblastoma Therapy

Gregory, J. V.; Kadiyala, P.; Doherty, R.; Cadena, M.; Habeel, S.; Ruoslahti, E.; Lowenstein, P. R.; Castro, M. G.; Lahann, J.

10.1101/862581 — bioengineering — Posted on 2019-12-03

2857 Multiplexed single-cell autism modeling reveals convergent mechanisms altering neuronal differentiation

Lalli, M. A.; Avey, D.; Dougherty, J. D.; Milbrandt, J.; Mitra, R. D.

10.1101/862680 — genomics — Posted on 2019-12-03

2858 Flagellum malfunctions trigger metaboly as an escape strategy in Euglena gracilis

Chen, Y.

10.1101/863282 — biophysics — Posted on 2019-12-03

2859 WHISKiT Physics: A three-dimensional mechanical model of the rat vibrissal array

Zweifel, N. O.; Bush, N. E.; Abraham, I.; Murphey, T. D.; Hartmann, M. J.

10.1101/862839 — neuroscience — Posted on 2019-12-03

2860 Computational principles of neural adaptation for binaural signal integration

Oess, T.; Ernst, M. O.; Neumann, H.

10.1101/863258 — neuroscience — Posted on 2019-12-03

2861 Improving Bacterial Ribosome Profiling Data Quality

Glaub, A. S.; Huptas, C.; Neuhaus, K.; Ardern, Z.

10.1101/863266 — molecular biology — Posted on 2019-12-03

2862 Premature termination codon readthrough in Drosophila varies in a developmental and tissue-specific manner

Chen, Y.-N.; Sun, T.; Bi, Z.; Ni, J.-Q.; Pastor-Pareja, J.; Javid, B.

10.1101/863027 — molecular biology — Posted on 2019-12-03

2863 Comparison of DNA extraction methods for non-marine molluscs: Is modified CTAB DNA extraction method more efficient than DNA extraction kits?

Chakraborty, S.; Saha, A.; Madhyastha, A. N. A.

10.1101/863167 — molecular biology — Posted on 2019-12-03

2864 Single-cell transcriptomics reveals diverse and complex gene expression alterations in human trisomy 18

Wang, J.; Chen, Z.; He, F.; Lee, T.; Cai, W.; Chen, W.; Zhang, L.; Miao, N.; Zeng, Z.; Hussain, G.; Sun, T.; Guo, Q.

10.1101/863332 — genetics — Posted on 2019-12-03

2865 The Use of GC-, Codon-, and Amino Acid-frequencies to Understand the Evolutionary Forces at a Genomic Scale.

Elofsson, A.

10.1101/863142 — evolutionary biology — Posted on 2019-12-03

2866 Shallow Genome Sequencing for Phylogenomics of Mycorrhizal Fungi from Endangered Orchids

Unruh, S. A.; Pires, C. A.; Zettler, L. W.; Erba, L.; Grigoriev, I. V.; Barry, K. W.; Daum, C.; Lipzen, A. V.; Stajich, J. E.

10.1101/862763 — evolutionary biology — Posted on 2019-12-03

2867 Multiplexing information flow through dynamic signalling systems

Minas, G.; Woodcock, D. J.; Ashall, L.; Harper, C.; White, M. R. H.; Rand, D. A.

10.1101/863159 — systems biology — Posted on 2019-12-03

2868 Direct ETTIN-auxin interaction controls chromatin state in gynoecium development

Kuhn, A.; Harborough, S. R.; McLaughlin, H.; Kepinski, S.; Ostergaard, L.

10.1101/863134 — plant biology — Posted on 2019-12-03

2869 SAMHD1 is a key regulator of the lineage-specific response of acute lymphoblastic leukaemias to nelarabine

Rothenburger, T.; McLaughlin, K.-M.; Herold, T.; Schneider, C.; Oellerich, T.; Rothweiler, F.; Feber, A.; Fenton, T. R.; Wass, M. N.; Keppler, O.; Michaelis, M. N.; Cinatl, J.

10.1101/863183 — pharmacology and toxicology — Posted on 2019-12-03

2870 Corollary Discharge Promotes a Sustained Motor State in a Neural Circuit for Navigation

Ji, N.; Venkatachalam, V.; Rodgers, H.; Hung, W.; Kawano, T.; Clark, C.; Lim, M.; Alkema, M. J.; Zhen, M. J.; Samuel, A.

10.1101/861559 — neuroscience — Posted on 2019-12-03

2871 Arabidopsis CPR5 regulates ethylene signaling via interacting with ETR1 N-terminus and controlling mRNAs nucleocytoplasmic transport

Chen, J.; Yu, Y.; Sui, X.; Qiao, L.; Dong, C.-H.

10.1101/862862 — plant biology — Posted on 2019-12-03

2872 Transient disruption of the inferior parietal lobule impairs action mindreading

Patri, J.-F.; Koul, A.; Soriano, M.; Valente, M.; Avenanti, A.; Cavallo, A.; Panzeri, S.; Becchio, C.

10.1101/862284 — neuroscience — Posted on 2019-12-03

2873 Nodal Fragility of Intracranial EEG Networks: Towards an EEG Fingerprint for the Epileptogenic Zone

Li, A.; Fitzgerald, Z.; Cajigas, I.; Brusko, D.; Claudio, A.; Jagid, J.; Kanner, A.; Hopp, J.; Chen, S.; Haagensen, J.; Johnson, E.; Crone, N.; Anderson, W.; Inati, S.; Zaghloul, K.; Bulacio, J.; Martinez, J.; Sarma, S.

10.1101/862797 — neuroscience — Posted on 2019-12-03

2874 Functional dissection of basal ganglia inhibitory input onto SNc dopaminergic neurons

Evans, R. C.; Twedell, E. L.; Zhu, M.; Ascencio, J.; Zhang, R.; Khaliq, Z. M.

10.1101/856617 — neuroscience — Posted on 2019-12-03

2875 Improving source modeling of auditory steady-state responses with frequency-specific brain maps

Farahani, E. D.; Wouters, J.; van Wieringen, A.

10.1101/859405 — neuroscience — Posted on 2019-12-03

2876 Exploring the Changing Landscape of Cell-to-Cell Variation After CTCF Knockdown via Single Cell RNA-seq

Wang, W.; Ren, G.; Hong, N.; Jin, W.

10.1101/862847 — genomics — Posted on 2019-12-03

2877 HB-EGF Signaling is Required for Glucose-Induced Pancreatic β-Cell Proliferation in Rats

Maachi, H.; Fergusson, G.; Ethier, M.; Brill, G. N.; Katz, L. S.; Honig, L. B.; Metukuri, M. R.; Scott, D. K.; Ghislain, J.; Poitout, V.

10.1101/683003 — cell biology — Posted on 2019-12-03

2878 Regulatory T cell expansion by a highly CD25-dependent IL-2 mutein arrests ongoing autoimmunity

Khoryati, L.; Pham, M. N.; Sherve, M.; Kumari, S.; Cook, K.; Pearson, J.; Bogdani, M.; Campbell, D. J.; Gavin, M. A.

10.1101/862789 — immunology — Posted on 2019-12-03

2879 ExpansionHunter Denovo: A computational method for locating known and novel repeat expansions in short-read sequencing data

10.1101/863035 — bioinformatics — Posted on 2019-12-03

2880 Gene expression pattern of vacuolar-iron transporter-like (VTL) genes in hexaploid wheat during metal stress

Sharma, S.; Kaur, G.; Kumar, A.; Meena, V.; Ram, H.; Kaur, J.; Pandey, A. K.

10.1101/863084 — plant biology — Posted on 2019-12-03

2881 Differential response trajectories to acute exercise in blood and muscle

Amar, D.; Lindholm, M. E.; Norrbom, J.; Wheeler, M. T.; Rivas, M. A.; ashley, e.

10.1101/863100 — physiology — Posted on 2019-12-03

2882 CD42b immunostaining as a marker for placental fibrinoid in normal pregnancy and complications

Zhang, P.

10.1101/860973 — pathology — Posted on 2019-12-03

2883 Identification of HIV-1 Envelope Mutations that Enhance Entry Using Macaque CD4 and CCR5

Roop, J. I.; Cassidy, N. A.; Dingens, A. S.; Bloom, J. D.; Overbaugh, J.

10.1101/863043 — microbiology — Posted on 2019-12-03

2884 Position-sensing established duringcompaction dictates cell fate in themammalian embryo

Royer, C.; Leonavicius, K.; Kip, A.; Fortin, D.; Nandi, K.; Vincent, A.; Jones, C.; Child, T.; Coward, K.; Graham, C.; Srinivas, S.

10.1101/856161 — developmental biology — Posted on 2019-12-03

2885 Syncytium cell growth increases IK1 contribution in human iPS-cardiomyocytes

Li, W.; Entcheva, E.

10.1101/862987 — bioengineering — Posted on 2019-12-03

2886 Deschloroclozapine: a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys

Nagai, Y.; Miyakawa, N.; Takuwa, H.; Hori, Y.; Oyama, K.; Ji, B.; Takahashi, M.; Huang, X.-P.; Slocum, S.; DiBerto, J. F.; Xiong, Y.; Urushihata, T.; Hirabayashi, T.; Fujimoto, A.; Mimura, K.; English, J. G.; Liu, J.; Inoue, K.-i.; Kumata, K.; Seki, C.; Ono, M.; Shimojo, M.; Zhang, M.-R.; Tomita, Y.; Suhara, T.; Takada, M.; Higuchi, M.; Jin, J.; Roth, B. L.; Minamimoto, T.

10.1101/854513 — neuroscience — Posted on 2019-12-03

2887 Linkage of a plasma zinc signature and impaired insulin receptor activation: Implications for the mechanism of type 2 diabetes mellitus

Prabhakar, S. M.

10.1101/849091 — molecular biology — Posted on 2019-12-03

2888 DCA promotes a novel tolerogenic program in CD4+ T cells by inhibiting CDK8

Arnett, A.; Moo, K. G.; Flynn, K. J.; Sundberg, T. B.; Johannessen, L.; Shamji, A. F.; Gray, N. S.; Decker, T.; Gersuk, V. H.; Levy, D. E.; Marie, I. J.; Rahman, Z. S.; Zheng, Y.; Linsley, P. S.; Xavier, R. J.; Khor, B.

10.1101/855429 — immunology — Posted on 2019-12-03

2889 Falciparum malaria from coastal Tanzania and Zanzibar remains highly connected despite effective control efforts on the archipelago

Morgan, A. P.; Brazeau, N. F.; Ngasala, B.; Mhamilawa, L. E.; Denton, M.; Msellem, M.; Morris, U.; Filer, D. L.; Aydemir, O.; Bailey, J. A.; Parr, J.; Martensson, A.; Bjorkman, A.; Juliano, J. J.

10.1101/863019 — genetics — Posted on 2019-12-03

2890 Comparative population genetic structure of two Ixodidae ticks (Ixodes ovatus and Haemaphysalis flava) in Niigata Prefecture, Japan

Regilme, M. A. F.; Sato, M.; Tamura, T.; Arai, R.; Sato, M. O.; Ikeda, S.; Doi, M.; Tanaka, K.; Gamboa, M.; Monaghan, M. T.; Watanabe, K.

10.1101/862904 — genetics — Posted on 2019-12-03

2891 Metastasis is altered through multiple processes regulated by the E2F1 transcription factor

Swiatnicki, M.; Andrechek, E.

10.1101/858068 — cancer biology — Posted on 2019-12-03

2892 QAlign: Aligning nanopore reads accurately using current-level modeling

Joshi, D. J.; Mao, S.; Kannan, S.; Diggavi, S.

10.1101/862813 — bioinformatics — Posted on 2019-12-03

2893 Monoubiquitination by the Fanconi Anemia core complex locks FANCI:FANCD2 on DNA in filamentous arrays

Tan, W.; van Twest, S.; Leis, A.; Bythell-Douglas, R.; Murphy, V. J.; Sharp, M.; Parker, M. W.; Crismani, W. M.; Deans, A. J.

10.1101/862805 — biochemistry — Posted on 2019-12-03

2894 LncRNA and predictive model to improve the diagnosis of clinically diagnosed pulmonary tuberculosis

Hu, X.; Chen, H.; Liao, S.; Bai, H.; Gupta, S.; Zhou, Y.; Zhou, J.; Jiao, L.; Wu, L.; Wang, M.; Chen, X.; Zhou, Y.; Lu, X.; Hu, T. Y.; Zhang, Z.; ying, B.

10.1101/863050 — molecular biology — Posted on 2019-12-03

2895 Proteoglycan IMPG2 shapes the interphotoreceptor matrix and modulates vision

Ramamurthy, V.; Salido, E. M.

10.1101/859116 — cell biology — Posted on 2019-12-03

2896 Biosynthesis of Iron Oxide Nanoparticles via Crocus sativus and their Antifungal Efficacy against Verticillium Wilt Pathogen Verticillium dahliae

Alam, T.; Akbar, F.; Ali, M.; Munis, M. F. H.; Khan, J.

10.1101/861401 — plant biology — Posted on 2019-12-03

2897 Microfluidic Removal of Teratoma-forming Cells from hiPSC-derived Neural Progenitor Cells

Wellmerling, K. M.; Lehmann, C.; Singh, A.; Kirby, B. J.

10.1101/830588 — developmental biology — Posted on 2019-12-03

2898 Health literacy assessment of primary care patients in Low and Middle Income Countries

Pasha, F.; Dreshaj, D.; Ismaili, A.; Sopjani, I.; Brooke, J.; Dreshaj, S.

10.1101/630533 — epidemiology — Posted on 2019-12-03

2899 Meta-analysis of hypoxic transcriptomes from public databases

Bono, H.; Hirota, K.

10.1101/267310 — bioinformatics — Posted on 2019-12-03

2900 Inferring Chromosome Radial Organization from Hi-CData

Das, P.; Shen, T.; McCord, R. P.

10.1101/863803 — bioinformatics — Posted on 2019-12-03

2901 Genetic aberrations in chromatin factors are pervasive, mutually exclusive, associated with a high mutational burden and improved response to checkpoint immunotherapy in cancer

Markovska, M.; Rosalia, R.; Stajkovska, A.; Mehandziska, S.; Janevska, M.; Kungulovski, I.; Mitrev, Z.; Kungulovski, G.

10.1101/861823 — genetics — Posted on 2019-12-03

2902 Ingested insecticide to control Aedes aegypti: Developing a novel dried attractive toxic sugar bait device for intra-domiciliary control

Sippy, R. J.; Rivera, G. E.; Sanchez, V.; Heras, F. H.; Morejon, B.; Ayala, E. B.; Hikida, R. A.; Lopes-Latorre, M. A.; Aguirre, A.; Stewart-Ibarra, A. M.; Larsen, D. A.; Neira, M.

10.1101/794065 — ecology — Posted on 2019-12-03

2903 Sub physiological temperature induces pervasive alternative splicing in Chinese hamster ovary cells

Tzani, I.; Monger, C.; Motheramgari, K.; Gallagher, C.; Hagan, R.; Kelly, P.; Costello, A.; Meiller, J.; Floris, P.; Zhang, L.; Clynes, M.; Bones, J.; Barron, N.; Clarke, C.

10.1101/863175 — cell biology — Posted on 2019-12-03

2904 GO: A functional reporter system to identify and enrich base editing activity

Katti, A.; Foronda, M.; Zimmerman, J.; Diaz, B. J.; Zafra, M. P.; Goswami, S.; Dow, L. E.

10.1101/862458 — bioengineering — Posted on 2019-12-03

2905 Local Glutamate-Mediated Dendritic Plateau Potentials Change the State of the Cortical Pyramidal Neuron

Gao, P. P.; Graham, J. W.; Zhou, W.-L. L.; Jang, J.; Angulo, S.; Dura-Bernal, S.; Hines, M.; Lytton, W. W.; Antic, S. D.

10.1101/828582 — neuroscience — Posted on 2019-12-03

2906 Effect of Sequence Depth and Length in Long-read Assembly of the Maize Inbred NC358

Ou, S.; LIU, J.; Chougule, K. M.; Fungtammasan, A.; Seetharam, A.; Stein, J.; Llaca, V.; MANCHANDA, N.; Gilbert, A. M.; Wei, X.; Chin, C.-S.; Hufnagel, D. E.; Pedersen, S.; Snodgrass, S.; Fengler, K.; Woodhouse, M.; Walenz, B. P.; Koren, S.; Phillippy, A. M.; Hannigan, B. T.; Dawe, R. K.; Hirsch, C.; Hufford, M.; Ware, D.

10.1101/858365 — genomics — Posted on 2019-12-03

2907 Mitochondrial genome of non-photosynthetic mycoheterotrophic plant Hypopitys monotropa,its structure, gene expression and RNA editing

Shtratnikova, V. Y.; Schelkunov, M. I.; Logacheva, M. D.; Penin, A. A.

10.1101/681718 — evolutionary biology — Posted on 2019-12-03

2908 Beta 1 Integrin Signaling Mediates Pancreatic Ductal Adenocarcinoma Resistance to MEK Inhibition

Brannon, A.; Drouillard, D.; Steele, N.; Sutherland, S.; Crawford, H.; Pasca di Magliano, M.

10.1101/862482 — cancer biology — Posted on 2019-12-03

2909 Effects of feeding treatment on growth rate and performance of primiparous Holstein dairy heifers

Le Cozler, Y.; Jurquet, J.; Bedere, N.

10.1101/760082 — zoology — Posted on 2019-12-03

2910 Evolution of C4 photosynthesis predicted by constraint-based modelling

Blaetke, M.-A.; Braeutigam, A.

10.1101/670547 — plant biology — Posted on 2019-12-03

2911 Acute inflammation alters energy metabolism in mice and humans: Role in sickness-induced hypoactivity, impaired cognition and delirium.

Kealy, J.; Murray, C.; Griffin, E. W.; Lopez-Rodriguez, A. B.; Healy, D.; Tortorelli, L. S.; Lowry, J. P.; Watne, L. O.; Cunningham, C.

10.1101/642967 — neuroscience — Posted on 2019-12-03

2912 TWIST1 homodimers and heterodimers orchestrate lineage-specific differentiation

Fan, X.; Waardenberg, A. J.; Demuth, M.; Osteil, P.; Sun, J.; Loebel, D. A. F.; Graham, M.; Tam, P. P. L.; Fossat, N.

10.1101/672824 — developmental biology — Posted on 2019-12-03

2913 Neural habituation enhances novelty detection: an EEG study of rapidly presented words

Jacob, L. P. L.; Huber, D. E.

10.1101/862516 — neuroscience — Posted on 2019-12-03

2914 Spatial attention and expectations rely on modality-specific and multisensory mechanisms

Zuanazzi, A.; Noppeney, U.

10.1101/847921 — neuroscience — Posted on 2019-12-03

2915 Enduring consequences of perinatal fentanyl exposure in mice

Alipio, J. B.; Brockett, A. T.; Fox, M. E.; Tennyson, S. S.; deBettencourt, C. A.; El-Metwally, D.; Francis, N. A.; Kanold, P. O.; Lobo, M. K.; Roesch, M. R.; Keller, A.

10.1101/735464 — neuroscience — Posted on 2019-12-03

2916 Pseudomonas aeruginosa is capable of natural transformation in biofilms

Nolan, L. M.; Turnbull, L.; Katrib, M.; Osvath, S. R.; Losa, D.; Whitchurch, C. B.

10.1101/859553 — microbiology — Posted on 2019-12-03

2917 Environmental stress maintains trioecy in nematode worms

Anderson, A. G.; Bubrig, L. T.; Fierst, J. L.

10.1101/862664 — evolutionary biology — Posted on 2019-12-03

2918 Comparing rates of introgression in parasitic feather lice with differing dispersal capabilities

Dona, J.; Sweet, A.; Johnson, K.

10.1101/527226 — evolutionary biology — Posted on 2019-12-03

2919 Trait-specific trade-offs prevent niche expansion in two parasites

Lievens, E. J.; Michalakis, Y.; Lenormand, T.

10.1101/621581 — evolutionary biology — Posted on 2019-12-03

2920 Complementation between pathological prion protein subassemblies to cross existing species barriers

Igel-Egalon, A.; Laferriere, F.; Tixador, P.; Moudjou, M.; Herzog, L.; Reine, F.; Torres, J. M.; Laude, H.; Rezaei, H.; Beringue, V.

10.1101/861278 — neuroscience — Posted on 2019-12-03

2921 Simulating emotions: An active inference model of emotional state inference and emotion concept learning

Smith, R.; Parr, T.; Friston, K. J.

10.1101/640813 — neuroscience — Posted on 2019-12-03

2922 Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

Woo, X. Y.; Giordano, J.; Srivastava, A.; Zhao, Z.-M.; Lloyd, M. W.; de Bruijn, R.; Suh, Y.-S.; Patidar, R.; Chen, L.; Scherer, S.; Bailey, M.; Yang, C.-H.; Cortes-Sanchez, E.; Xi, Y.; Wang, J.; Wickramasinghe, J.; Kossenkov, A. V.; Rebecca, V.; Sun, H.; Mashl, R. J.; Davies, S.; Jeon, R.; Frech, C.; Randjelovic, J.; Rosains, J.; Galimi, F.; Bertotti, A.; Lafferty, A.; O'Farrell, A. C.; Modave, E.; Lambrechts, D.; ter Brugge, P.; Serra, V.; Marangoni, E.; El Botty, R.; Kim, H.; Kim, J.-I.; Yang, H.-K.; Lee, C.; Dean, D. A.; Davis-Dusenbery, B.; Evrard, Y.; Doroshow, J.; Welm, A. L.; Welm, B. E

10.1101/861393 — cancer biology — Posted on 2019-12-03

2923 Collagen-based scaffolds with infused anti-VEGF release system as potential cornea substitute for high-risk keratoplasty: An in vitro evaluation

Buznyk, O.; Azharuddin, M.; Islam, M. M.; Fagerholm, P.; Pasyechnikova, N.; Patra, H. K.

10.1101/862607 — bioengineering — Posted on 2019-12-03

2924 The Embodied Nature of Well-Timed Behavior

Safaie, M.; Jurado-Parras, M.-T.; Sarno, S.; Louis, J.; Karoutchi, C.; Petit, L. F.; Pasquet, M. O.; Eloy, C.; Robbe, D.

10.1101/716274 — animal behavior and cognition — Posted on 2019-12-03

2925 Disruption of TFIIH activities generates a stress gene expression response and reveals possible new targets against cancer

Uriostegui Arcos, M.; Aguayo Ortiz, R.; Valencia Morales, M. d. P.; Melchy Perez, E.; Rosenstein, Y.; Dominguez, L.; Zurita, M.

10.1101/862508 — molecular biology — Posted on 2019-12-03

2926 Synovial fibroblasts contribute to the genetic risk of rheumatoid arthritis through the synergistic action of cytokines

Tsuchiya, H.; Ota, M.; Sumitomo, S.; Ishigaki, K.; Suzuki, A.; Sakata, T.; Tsuchida, Y.; Inui, H.; Hirose, J.; Kochi, Y.; Kadono, Y.; Shirahige, K.; Tanaka, S.; Yamamoto, K.; Fujio, K.

10.1101/861781 — immunology — Posted on 2019-12-03

2927 Expanding the Chinese hamster ovary cell long non-coding RNA transcriptome using RNASeq

Motheramgari, K.; Valdes-Bango Curell, R.; Tzani, I.; Gallagher, C.; Castro Rivadeneyra, M.; Zhang, L.; Barron, N.; Clarke, C.

10.1101/863241 — cell biology — Posted on 2019-12-03

2928 Single-cell transcriptome analysis reveals TOX as a promoting factor for T-cell exhaustion and a predictor for anti-PD1 responses in human cancer

Kim, K.; Park, S.; Park, S. Y.; Kim, G.; Park, S. M.; Cho, J.-W.; Kim, D. H.; Park, Y. M.; Koh, Y. W.; Kim, H. R.; Ha, S.-J.; Lee, I.

10.1101/641316 — cancer biology — Posted on 2019-12-03

2929 Implicit bias is strongest when assessing top candidates

Andersson, E. R.; Hagberg, C.; Hagg, S.

10.1101/859298 — scientific communication and education — Posted on 2019-12-03

2930 Connectomic consistency: a systematic stability analysisof structural and functional connectivity

Osmanlioglu, Y.; Alappatt, J. A.; Parker, D.; Verma, R.

10.1101/862730 — neuroscience — Posted on 2019-12-03

2931 Spatial suppression in visual motion perception is driven by inhibition: evidence from MEG gamma oscillations

Orekhova, E. V.; Ekaterina, R. N.; Viktoria, M. O.; Prokofyev, A.; Obukhova, T. S.; Nikolaeva, A. Y.; Schneiderman, J. F.; Stroganova, T. A.

10.1101/861765 — neuroscience — Posted on 2019-12-03

2932 Purinergic signaling in cochlear supporting cells reduces hair cell excitability by increasing the extracellular space

Babola, T. A.; Kersbergen, C. J.; Wang, H. C.; Bergles, D. E.

10.1101/852756 — neuroscience — Posted on 2019-12-03

2933 Local cortical desynchronization and pupil-linked arousal differentially shape brain states for optimal sensory performance

Waschke, L.; Tune, S.; Obleser, J.

10.1101/582353 — neuroscience — Posted on 2019-12-03

2934 Alongshan virus in Russia

10.1101/862573 — molecular biology — Posted on 2019-12-03

2935 A minimal CRISPR-Cas3 system for genome engineering

Csorgo, B.; Leon, L. M.; Chau-Ly, I. J.; Vasquez-Rifo, A.; Berry, J. D.; Mahendra, C.; Crawford, E.; Lewis, J. D.; Bondy-Denomy, J.

10.1101/860999 — molecular biology — Posted on 2019-12-03

2936 In Vivo Dual RNA-Seq Analysis Reveals the Basis for Differential Tissue Tropism of Clinical Isolates of Streptococcus pneumoniae

Minhas, V.; Aprianto, R.; McAllister, L. J.; Wang, H.; David, S. C.; McLean, K. T.; Comerford, I.; McColl, S. R.; Paton, J. C.; Veening, J.-W.; Trappetti, C.

10.1101/862755 — microbiology — Posted on 2019-12-03

2937 The somatic genetic and epigenetic mutation rate in a wild long-lived perennial Populus trichocarpa

Hofmeister, B. T.; Denkena, J.; Colome-Tatche, M.; Shahryary Dizaji, Y.; Hazarika, R.; Grimwood, J.; Mamid, S.; Jenkins, J.; Grabowski, P. P.; Sreedasyam, A.; Shu, S.; Barry, K.; Lail, K.; Adam, C.; Lipzen, A.; Sorek, R.; Kudrna, D.; Talag, J.; Wing, R.; Hall, D. W.; Tuskan, G. A.; Schmutz, J.; Johannes, F.; Schmitz, R. J.

10.1101/862623 — genomics — Posted on 2019-12-03

2938 Sub physiological temperature induces pervasive alternative splicing in Chinese hamster ovary cells

Clarke, C.; Tzani, I.; Monger, C.; Motheramgari, K.; Gallagher, C.; Hagan, R.; Costello, A.; Meiller, J.; Floris, P.; Zhang, L.; Clynes, M.; Bones, J.; Barron, N.; Kelly, P.

10.1101/863175 — cell biology — Posted on 2019-12-03

2939 Slow recovery from inbreeding depression generated by the complex genetic architecture of segregating deleterious mutations

Adams, P. E.; Crist, A. L.; Young, E. M.; Willis, J. H.; Phillips, P. C.; Fierst, J. L.

10.1101/862631 — evolutionary biology — Posted on 2019-12-03

2940 Flexible Experimental Designs for Valid Single-cell RNA-sequencing Experiments Allowing Batch Effects Correction

Song, F.; Chan, G. M.; Wei, Y.

10.1101/533372 — bioinformatics — Posted on 2019-12-03

2941 Ex-situ cultivation of Isoetes cangae and Isoetes serracarajensis (Isoetaceae) two endemic species from Brazilian Amazon

Zandonadi, D. B.; Martins, R. L.; Prado, L. A. d. S.; Duarte, H. M.; Santos, M. P.; Calderon, E. N.; Fernandes, A. C. A.; Santos, Q. S.; Nunes, F. J. G.; Ribeiro, L. C. F.; Fernandes, T. N.; Castilho, A.; Esteves, F. d. A.

10.1101/861351 — plant biology — Posted on 2019-12-03

2942 Vaping Perpetuates Cardiac Electrical Instability

Abou Assali, O.; Chang, M.; Reiser, M.; Kanithi, M.; Soni, R.; Chidipi, B.; Noujaim, S.

10.1101/862441 — physiology — Posted on 2019-12-03

2943 Inducible cell-specific mouse models for paired epigenetic and transcriptomic studies of microglia and astroglia

Chucair-Elliott, A. J.; Ocanas, S. R.; Stanford, D. R.; Ansere, V. A.; Buettner, K. B.; Porter, H.; Eliason, N. L.; Reid, J.; Sharpe, A. L.; Stout, M. B.; Beckstead, M. J.; Miller, B. F.; Richardson, A.; Freeman, W. M.

10.1101/862722 — neuroscience — Posted on 2019-12-03

2944 Digital polymerase chain reaction in an array of microfluidic printed droplets

Men, Y.; Li, J.; Ao, T.; Li, Z.; Wu, B.; Li, W.; Ding, Y.; Tseng, K.-H.; Tan, W.; Pan, T.; Li, B.; Chen, Y.

10.1101/860411 — molecular biology — Posted on 2019-12-03

2945 Robotic microscopy for everyone: the OpenFlexure Microscope

Collins, J. T.; Knapper, J.; Stirling, J.; Mduda, J.; Mkindi, C.; Mayagaya, V.; Mwakajinga, G. A.; Nyakyi, P. T.; Sanga, V. L.; Carbery, D.; White, L.; Dale, S.; Lim, Z. J.; Baumberg, J. J.; Cicuta, P.; McDermott, S.; Vodenicharski, B.; Bowman, R.

10.1101/861856 — microbiology — Posted on 2019-12-03

2946 Processing of the SARS-CoV pp1a/ab nsp7-10 region

Krichel, B.; Falke, S.; Hilgenfeld, R.; Redecke, L.; Uetrecht, C.

10.1101/860049 — biophysics — Posted on 2019-12-03

2947 Flavor-specific enhancement of electronic cigarette liquid consumption and preference in mice

Wong, A. L.; McElroy, S. M.; Robinson, J. M.; Mulloy, S. M.; El Banna, F. K.; Harris, A. C.; LeSage, M. G.; Lee, A. M.

10.1101/862524 — pharmacology and toxicology — Posted on 2019-12-03

2948 Response nonlinearities in networks of spiking neurons

Sanzeni, A.; Histed, M. H.; Brunel, N.

10.1101/856831 — neuroscience — Posted on 2019-12-03

2949 Pseudomonas aeruginosa is capable of natural transformation in biofilms

Nolan, L. M.; Turnbull, L.; Katrib, M.; Osvath, S. R.; Losa, D.; Whitchurch, C. B.

10.1101/859553 — microbiology — Posted on 2019-12-03

Akarca, A.; Ellery, P.; Segal, A. W.; Marafioti, T.

10.1101/861807 — immunology — Posted on 2019-12-03

2951 An Erg driven transcriptional program controls B-lymphopoiesis

Ng, A. P.; Coughlan, H. D.; Hediyeh-zadeh, S.; Behrens, K.; Johanson, T. M.; Low, M. S. Y.; Bell, C. C.; Gilan, O.; Chan, Y.-C.; Kueh, A. J.; Boudier, T.; DiRago, L.; Hyland, C. D.; Ierino, H.; Mifsud, S.; Viney, E.; Willson, T.; Dawson, M. A.; Allan, R. S.; Herold, M. J.; Rogers, K.; Tarlinton, D. M.; Smyth, G.; Davis, M. J.; Nutt, S. L.; Alexander, W. S.

10.1101/861542 — immunology — Posted on 2019-12-03

2952 Nearest-neighbor Projected-Distance Regression (NPDR) for detecting network interactions with adjustments for multiple tests and confounding

Le, T. T.; Dawkins, B. A.; McKinney, B. A.

10.1101/861492 — genetics — Posted on 2019-12-03

2953 Assessing the impacts of agriculture and its trade on Philippine biodiversity

Ortiz, A. M. D.; Torres, J. N. V.

10.1101/861815 — ecology — Posted on 2019-12-03

2954 Deep learning-based methods for individual recognition in small birds

Ferreira, A. C.; Silva, L. R.; Renna, F.; Brandl, H. B.; Renoult, J. P.; Farine, D. R.; Covas, R.; Doutrelant, C.

10.1101/862557 — ecology — Posted on 2019-12-03

2955 Individual differences in dopamine function underlying the balance between model-based and model-free control

Lee, Y.; Deserno, L.; Kroemer, N.; Pooseh, S.; Oehme, L.; Mueller, D.; Goschke, T.; Huys, Q.; Smolka, M. N.

10.1101/860361 — neuroscience — Posted on 2019-12-03

2956 A synthetic Calvin cycle enables autotrophic growth in yeast

Gassler, T.; Sauer, M.; Gasser, B.; Mattanovich, D.; Steiger, M. G.

10.1101/862599 — synthetic biology — Posted on 2019-12-03

2957 IRSp53 shapes the plasma membrane and controls polarized transport at the nascent lumen during epithelial morphogenesis

Bisi, S.; Rizvi, A.; Marchesi, S.; Carra, D.; Beznoussenko, G.; Ferrara, I.; Deflorian, G.; Mironov, A.; Bertalot, G.; Pisati, F.; Oldani, A.; Cattaneo, A.; Pece, S.; Viale, G.; Bachi, A.; Tripodo, C.; Scita, G.; Disanza, A.

10.1101/856369 — developmental biology — Posted on 2019-12-03

2958 The association of self-reported sleep quality and obesity in Kuwait using the Pittsburgh Sleep Quality Index (PSQI)

Alghaith, A.; Azim, R.; Ahmad, R.; Al-rashed, f.

10.1101/862060 — evolutionary biology — Posted on 2019-12-03

2959 Organogenesis and Distribution of the Ocular Lymphatic Vessels in the Anterior Eye: Implication to Glaucoma Surgery Site Selection

Wu, Y.; Seong, Y. J.; Kin, L.; Choi, D.; Park, E.; Daghlian, G.; Jung, E.; Bui, K.; Luping, Z.; Madhavan, S.; Saren, D.; Patill, D.; Chin, D.; Cho, I.-T.; Wong, A.; Heur, M.; Zhang-Nunes, S.; Tan, J.; Ema, M.; Huang, A. S.; Hong, Y.-K.

10.1101/847970 — developmental biology — Posted on 2019-12-03

2960 Apical Constriction Reversal upon Mitotic Entry Underlies Different Morphogenetic Outcomes of Cell Division

Ko, C. S.; Kalakuntla, P.; Martin, A. C.

10.1101/862821 — developmental biology — Posted on 2019-12-03

2961 Precise temporal regulation of post-transcriptional repressors is required for an orderly Drosophila maternal-to-zygotic transition

Cao, W. X.; Kabelitz, S.; Gupta, M.; Yeung, E.; Lin, S.; Rammelt, C.; Ihling, C.; Pekovic, F.; Low, T. C. H.; Siddiqui, N. U.; Cheng, M. H. K.; Angers, S.; Smibert, C. A.; Wühr, M.; Wahle, E.; Lipshitz, H. D.

10.1101/862490 — developmental biology — Posted on 2019-12-03

2962 Mosaic metabolic ageing: Basal and standard metabolic rate age in opposite directions and and independent of environmental quality, sex or lifespan in a passerine

Briga, M.; Verhulst, S.

10.1101/844266 — ecology — Posted on 2019-12-03

2963 Acoustic contamination of electrophysiological brain signals during speech production and sound perception

Roussel, P.; Le Godais, G.; Bocquelet, F.; Palma, M.; Hongjie, J.; Zhang, S.; Kahane, P.; Chabardes, S.; Yvert, B.

10.1101/722207 — neuroscience — Posted on 2019-12-03

2964 Network Inference from Multi-omic Data Uncovers Dynamic Transcriptional Regulation Modules in Pathogenic Fungus Fusarium graminearum

Guo, L.; Ji, M.; Ye, K.

10.1101/858498 — microbiology — Posted on 2019-12-03

2965 The potential for "spillover" in outpatient antibiotic stewardship interventions among US states

Olesen, S. W.; Lipsitch, M.; Grad, Y. H.

10.1101/536714 — epidemiology — Posted on 2019-12-03

2966 Estimating Northern Fur Seal Pup Production: A case study of batch mark abundance estimation

Johnson, D. S.; Towell, R.; Baker, J.

10.1101/772350 — ecology — Posted on 2019-12-03

2967 Extended Bayesian inference incorporating symmetry bias

Shinohara, S.; Manome, N.; Suzuki, K.; Chung, U.-i.; Takahashi, T.; Gunji, Y.; Nakajima, Y.; Mitsuyoshi, S.

10.1101/698290 — animal behavior and cognition — Posted on 2019-12-03

2968 Impact of small RNAs in retrograde signalling pathways in Arabidopsis thaliana

Habermann, K.; Frank, W.; Arif, A. M.; Tiwari, B.; Krantz, M.; Adler, S. O.; Klipp, E.

10.1101/798900 — plant biology — Posted on 2019-12-03

2969 Information content of cheek and lip colour in relation to the timing of ovulation in women

Rigaill, L.

10.1101/859801 — physiology — Posted on 2019-12-03

2970 CofActor: A light and redox-gated optogenetic clustering tool to study abnormal cytoskeletal dynamics in stressed cells

Salem, F. B.; Prabhu, V. V.; Kuyateh, A.-B.; Bunner, W. P.; Murashov, A. K.; Szatmari, E. M.; Hughes, R. M.

10.1101/857706 — neuroscience — Posted on 2019-12-03

2971 The head direction circuit of two insect species

Pisokas, I.; Heinze, S.; Webb, B.

10.1101/854521 — neuroscience — Posted on 2019-12-03

2972 Novel tetraplex qPCR assays for simultaneous detection and identification of Xylella fastidiosa subspecies in plant tissues

Dupas, E.; Briand, M.; Jacques, M.-A.; Cesbron, S.

10.1101/699371 — molecular biology — Posted on 2019-12-03

2973 Three complete genome sequences of Penguin megrivirus from ornithogenic soil, Adelie penguin and Weddell seal of Antarctica

Aasdev, A.; Mishra, A.; Nair, M.; Pawar, S. D.; Dubey, C. K.; Bhatia, S.; Dastidar, P. G.; Singh, V. P.; Raut, A. A.

10.1101/858043 — microbiology — Posted on 2019-12-03

2974 A simple device to immobilize protists for electrophysiology and microinjection

Kulkarni, A.; Escoubet, N.; Pontani, L.-L.; Prevost, A. M.; Brette, R.

10.1101/859413 — microbiology — Posted on 2019-12-03

2975 The landscape of coadaptation in Vibrio parahaemolyticus

Cui, Y.; Yang, C.; Qiu, H.; Wang, H.; Yang, R.; Falush, D.

10.1101/373936 — microbiology — Posted on 2019-12-03

2976 Functions of Gtf2i and Gtf2ird1 in the developing brain: transcription, DNA-binding, and long term behavioral consequences.

Kopp, N. D.; Nygaard, K. R.; McCullough, K. B.; Maloney, S. E.; Gabel, H. W.; Dougherty, J.

10.1101/854851 — genetics — Posted on 2019-12-03

2977 Nanopore sequencing of the glucocerebrosidase (GBA) gene in a New Zealand Parkinsons disease cohort

Graham, O. E. E.; Pitcher, T. L.; Liau, Y.; Miller, A.; Dalrymple-Alford, J. C.; Anderson, T. J.; Kennedy, M. A.

10.1101/748335 — genetics — Posted on 2019-12-03

2978 Genome-Wide Association Study of Brain Connectivity Changes for Alzheimer's Disease

Elsheikh, S. S. M.; Chimusa, E. R.; Mulder, N. J.; Crimi, A.

10.1101/342436 — bioinformatics — Posted on 2019-12-03

2979 Tagging allows faithful tracing of expression and enhances biochemical detection of Ran Binding Protein 9 in vivo and reveals its interaction with Nucleolin.

Soliman, S.; Stark, A. E.; Gardner, M.; Harshman, S. W.; Breece, C. C.; Amari, F.; Orlacchio, A.; Chen, M.; Tessari, A.; Martin, J. A.; Visone, R.; Freitas, M. A.; La Perle, K.; Palmieri, D.; COPPOLA, V.

10.1101/745174 — bioengineering — Posted on 2019-12-03

2980 Enhanced leaky sex expression is an adaptive plastic response to pollen limitation in the dioecious plant Mercurialis annua

Cossard, G.; Pannell, J. R.

10.1101/703009 — evolutionary biology — Posted on 2019-12-03

2981 Thermal preference influences depth use but not biomass of predatory fishes in response to lake morphometry

Bartley, T. J.; Guzzo, M. M.; Cazelles, K.; Verville, A.; McMeans, B. C.; McCann, K. S.

10.1101/572925 — ecology — Posted on 2019-12-03

2982 MUSCLE MITOCHONDRIAL CAPACITY AND ENDURANCE IN ADULTS WITH TYPE 1 DIABETES

Hewgley, R. A.; Moore, B. T.; Willingham, T. B.; Jenkins, N. T.; McCully, K. K.

10.1101/862086 — physiology — Posted on 2019-12-02

2983 Assigning a role for chemosensory signal transduction in Campylobacter jejuni biofilms using a combined omics approach

Korolik, V.; Tram, G.; Klare, W. P.; Cain, J. A.; Mourad, B.; Cordwell, S. J.; Day, C. J.

10.1101/862151 — microbiology — Posted on 2019-12-02

2984 Tuning antiviral CD8 T-cell response via proline-altered peptide ligand vaccination

Achour, A.; Duru, A. D.; Sun, R.; Allerbring, E. B.; Chadderton, J.; Kadri, N.; Han, X.; Uchtenhagen, H.; Madhurantakam, C.; Pellegrino, S.; Sandalova, T.; Nygren, P.-A.; Turner, S. J.

10.1101/862144 — immunology — Posted on 2019-12-02

2985 Australian native flower colours: does nectar reward drive bee pollinator flower preferences?

Dyer, A. G.; Shrestha, M.; Garcia, J. E.; Burd, M.

10.1101/862110 — ecology — Posted on 2019-12-02

2986 Global gene expression profile during low temperature in the brain of grass carp (Ctenopharyngodon idellus)

Shi, M.; Zhang, Q.; Li, Y.; Zhang, W.; Liao, L.; Cheng, Y.; Jiang, Y.; Huang, X.; Duan, Y.; Xia, L.; Ye, W.; Wang, Y.; Xia, X.-Q.

10.1101/862102 — zoology — Posted on 2019-12-02

2987 Is the replication crisis a problem for biologists? A geometric morphometric approach.

Vrdoljak, J.; Sanchez, K. I.; Arreola-Ramos, R.; Diaz Huesa, E. G.; Villagra, A.; Avila, L. J.; Morando, M.

10.1101/862052 — scientific communication and education — Posted on 2019-12-02

2988 Neural Encoding for Human Visual Cortex with Deep Neural Networks Learning "What" and "Where"

Wang, H.; Huang, L.; Du, C.; Li, D.; Wang, B.; He, H.

10.1101/861989 — neuroscience — Posted on 2019-12-02

2989 The MITF paralog tfec is required in neural crest development for fate specification of the iridophore lineage from a multipotent pigment cell progenitor

Petratou, K.; Spencer, S. A.; Kelsh, R. N.; Lister, J. A.

10.1101/862011 — developmental biology — Posted on 2019-12-02

2990 Effects of host plants nutrient on the nutrient in Bradysia cellarum and Bradysia impatiens

Gou, Y.; Quandahor, P.; Zhang, Y.; Liu, C.

10.1101/862094 — zoology — Posted on 2019-12-02

2991 Two-variable nullcline analysis of ionic general equilibrium predicts calcium homeostasis in ventricular myocytes

Alvarez-Lacalle, E.; Conesa, D.; Echebarria, B.; Penaranda, A.; Cantalapiedra, I. R.; Shiferaw, Y.

10.1101/861997 — systems biology — Posted on 2019-12-02

2992 Phylobioactive hotspots identified through multidimensional profiling of botanical drugs used to treat Chagas disease in Bolivia and Dioscorides' De Materia Medica

Salm, A.; Krishnan, S. R.; Collu, M.; Danton, O.; Hamburger, M.; Leonti, M.; Almanza, G.; Gertsch, J.

10.1101/862029 — pharmacology and toxicology — Posted on 2019-12-02

2993 Annexin A2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and Ebola virus infections

Su, Z.; Chang, Q.; Drelich, A.; Shelite, T.; Judy, B.; Liu, Y.; Xiao, J.; Zhou, C.; He, X.; Saito, T.; Tang, S.; Soong, L.; Wakamiya, M.; Fang, X.; Bukreyev, A.; Ksiazek, T.; Russell, W. K.; Gong, B.

10.1101/862037 — pathology — Posted on 2019-12-02

2994 Role of centromere sites in activation of ParB proteins for partition complex assembly

Audibert, S.; Tanguy-le-Gac, N.; Rech, J.; Turlan, C.; Bouet, J.-Y.; Bystricky, K.; Lane, D.

10.1101/862136 — microbiology — Posted on 2019-12-02

2995 Different detection capabilities by mycological media for Candida isolates from mono- or dual-species cultures

De Angelis, G.; Menchinelli, G.; Torelli, R.; De Carolis, E.; Posteraro, P.; Sanguinetti, M.; Posteraro, B.

10.1101/862078 — microbiology — Posted on 2019-12-02

2996 Robustness and parameter geography in post-translational modification systems

Nam, K.-M.; Gyori, B. M.; Amethyst, S. V.; Bates, D. J.; Gunawardena, J.

10.1101/862003 — systems biology — Posted on 2019-12-02

2997 Reticulocyte Infection Leads to Altered Behaviour, Drug Sensitivity and Host Cell Remodelling by Plasmodium falciparum.

Chandramohanadas, R.; Naidu, R.; Chu, T. T.; Tripathi, J.; Hu, Y.; Subramanian, G.; Tong, J. X.; Tripathi, P.; Fang, K.; Tan, K. S.; Lim, C. T.; Chan, J. K.; Bozdech, Z.

10.1101/862169 — microbiology — Posted on 2019-12-02

2998 Improving reliability in clinical neuroimaging: a study in transgender persons

Sorouri Khorashad, B.; Khazai, B.; Talaei, A.; Acar, F.; Hudson, A. R.; Borji, N.; Saberi, H.; Aminzadeh, B.; Mueller, S.

10.1101/861864 — neuroscience — Posted on 2019-12-02

2999 Differences in berry primary and secondary metabolisms identified by transcriptomic and metabolic profiling of two table grape color somatic variants

Santibanez, C.; Meyer, C.; Martinez, L.; Moyano, T.; Lunn, J.; Feil, R.; Dai, Z.; Carrasco, D.; Arroyo-Garcia, R.; Hilbert, G.; Renaud, C.; Delrot, S.; Manke, F.; Gutierrez, R. A.; Matus, J. T.; Gomes, E.; Arce-Johnson, P.

10.1101/861120 — plant biology — Posted on 2019-12-02

3000 Distinctive epigenomic alterations in NF1-deficient cutaneous and plexiform neurofibromas drive differential MKK/P38 signaling

Grit, J. L.; Johnson, B. K.; Essenburg, C. J.; Dischinger, P. S.; Campbell, S.; Triche, T. J.; Graveel, C. R.; Steensma, M. R.

10.1101/833467 — genomics — Posted on 2019-12-02

3001 Massively parallel disruption of enhancers active during human corticogenesis

Geller, E.; Gockley, J.; Emera, D.; Uebbing, S.; Cotney, J.; Noonan, J. P.

10.1101/852673 — genomics — Posted on 2019-12-02

3002 High-force magnetic tweezers with hysteresis-free force feedback

Kah, D.; Dürrbeck, C.; Schneider, W.; Fabry, B.; Gerum, R.

10.1101/862342 — biophysics — Posted on 2019-12-02

3003 Genomics of Human Respiratory Syncytial Virus Vaccine Attenuation

Junier, T.; Kaiser, L.; Chaturvedi, N.; Fellay, J.

10.1101/862185 — genomics — Posted on 2019-12-02

3004 Gene regulatory effects of a large chromosomal inversion in highland maize

Crow, T. M.; Ta, J.; Nojoomi, S.; Aguilar-Rangel, M. R.; Torres Rodriguez, J. V.; Gates, D.; Rellan-Alvarez, R.; Sawers, R.; Runcie, D. E.

10.1101/861583 — genomics — Posted on 2019-12-02

3005 Cluster Analysis Based on Fasting and Postprandial Plasma Glucose and Insulin Concentrations

Altuve, M. A.; Severeyn, E.

10.1101/861468 — bioengineering — Posted on 2019-12-02

3006 Studying RNA#8211;DNA interactome by Red-C identifies noncoding RNAs associated with repressed chromatin compartment and reveals transcription dynamics

Gavrilov, A. A.; Zharikova, A. A.; Galitsyna, A. A.; Luzhin, A. V.; Rubanova, N. M.; Golov, A. K.; Petrova, N. V.; Logacheva, M. D.; Kantidze, O. L.; Ulianov, S. V.; Magnitov, M. D.; Mironov, A. A.; Razin, S. V.

10.1101/859504 — genomics — Posted on 2019-12-02

3007 Prediction of fruit texture with training population optimization for efficient genomic selection in apple

Roth, M.; Di Guardo, M.; Guerra, W.; Muranty, H.; Patocchi, A.; Costa, F.

10.1101/862193 — genetics — Posted on 2019-12-02

3008 Nature protection across countries: Do size and power matter?

Baldi, G.

10.1101/861971 — ecology — Posted on 2019-12-02

3009 Data-driven modeling of group formation in the fission-fusion dynamics of Bechstein's bats

Perony, N.; Kerth, G.; Schweitzer, F.

10.1101/862219 — ecology — Posted on 2019-12-02

3010 Role of protein dynamics in enthalpy-driven recognition of topologically distinct dsRNAs by dsRBDs

Paithankar, H.; Chugh, J.

10.1101/862326 — biophysics — Posted on 2019-12-02

3011 Swimming performance traits of twenty-one Australian fish species: a fish passage management tool for use in modified freshwater systems

Watson, J. R.; Goodrich, H. R.; Cramp, R. L.; Gordos, M. A.; Yan, Y.; Ward, P. J.; Franklin, C. E.

10.1101/861898 — zoology — Posted on 2019-12-02

3012 The accidental ally: Nucleosomal barriers can accelerate cohesin mediated loop formation in chromatin

Maji, A.; Padinhateeri, R.; Mitra, M. K.

10.1101/861161 — biophysics — Posted on 2019-12-02

3013 Arabidopsis ROOT PHOTOTROPISM2 is a Light-Dependent Dynamic Modulator of Phototropin1

Kimura, T.; Tsuchida-Mayama, T.; Imai, H.; Okajima, K.; Ito, K.; Sakai, T.

10.1101/862649 — plant biology — Posted on 2019-12-02

3014 Do deep neural networks see the way we do?

Jacob, G.; R. T., P.; Katti, H.; Arun, S.

10.1101/860759 — neuroscience — Posted on 2019-12-02

3015 Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models

Sebastian Monasor, L.; Mueller, S. A.; Colombo, A.; Koenig, J.; Roth, S.; Liesz, A.; Berghofer, A.; Saito, T.; Saido, T.; Herms, J.; Willem, M.; Haass, C.; Lichtenthaler, S. F.; Tahirovic, S.

10.1101/861146 — neuroscience — Posted on 2019-12-02

3016 Removal of Scanner Effects in Covariance Improves Multivariate Pattern Analysis in Neuroimaging Data

Chen, A. A.; Beer, J. C.; Tustison, N. J.; Cook, P. A.; Shinohara, R. T.; Shou, H.

10.1101/858415 — neuroscience — Posted on 2019-12-02

3017 Effect Of Inflammatory Pain On Alcohol-Induced Dopamine Release In The Nucleus Accumbens: Behavioural Implications In Rat Models.

Campos-Jurado, Y.; Lorente, J. D.; Gonzalez-Romero, J. L.; Granero, L.; Polache, A.; Hipolito, L.

10.1101/862318 — neuroscience — Posted on 2019-12-02

3018 Environmental Oxygen Regulates Astrocyte Proliferation to Guide Angiogenesis during Retinal Development

Perelli, R. M.; O'Sullivan, M. L.; Zarnick, S.; Kay, J. N.

10.1101/861948 — neuroscience — Posted on 2019-12-02

3019 Use of multi-flip angle measurements to account for transmit inhomogeneity and non-Gaussian diffusion in DW-SSFP

Tendler, B. C.; Foxley, S.; Hernandez-Fernandez, M.; Cottaar, M.; Scott, C.; Ansorge, O.; Miller, K.; Jbabdi, S.

10.1101/861880 — neuroscience — Posted on 2019-12-02

3020 The Multispecies Coalescent Model Outperforms Concatenation across Diverse Phylogenomic Data Sets

Jiang, X.; Edwards, S. V.; Liu, L.

10.1101/860809 — evolutionary biology — Posted on 2019-12-02

3021 Signaling compartment at the ciliary tip is formed and maintained by intraflagellar transport and functions as sensitive salt detector

van der Burght, S. N.; Rademakers, S.; Johnson, J.-L.; Li, C.; Leroux, M. R.; Jansen, G.

10.1101/861955 — cell biology — Posted on 2019-12-02

3022 Cryogenic OrbiSIMS Localizes Semi-Volatile Molecules in Biological Tissues

Newell, C. L.; Vorng, J.-L.; MacRae, J. I.; Gilmore, I.; Gould, A. P.

10.1101/862391 — biochemistry — Posted on 2019-12-02

3023 Using real-time fluorescence and deformability cytometry and deep learning to transfer molecular specificity to label-free sorting

Nawaz, A. A.; Urbanska, M.; Herbig, M.; Nötzel, M.; Kräter, M.; Rosendahl, P.; Herold, C.; Toepfner, N.; Kubankova, M.; Goswami, R.; Abuhattum, S.; Reichel, F.; Müller, P.; Taubenberger, A. V.; Girardo, S.; Jacobi, A.; Guck, J.

10.1101/862227 — biophysics — Posted on 2019-12-02

3024 The influence of environmental setting on the community ecology of Ediacaran organisms

Mitchell, E. G.; Bobkov, N.; Bykova, N.; Dhungana, A.; Kolesnikov, A.; Hogarth, I. R. P.; Liu, A. G.; Mustill, T.; Sozonov, N.; Xiao, S.; Grazhdankin, D. V.

10.1101/861906 — paleontology — Posted on 2019-12-02

3025 Decoupling of Dopamine Release and Neural Activity in Major Depressive Disorder during Reward Processing Assessed by Simultaneous fPET-fMRI

Zhang, X.; Wang, F.; Hamilton, J. P.; Sacchet, M. D.; Chen, J. E.; Khalighi, M.; Gotlib, I. H.; Glover, G. H.

10.1101/861534 — neuroscience — Posted on 2019-12-02

3026 Prolonged anesthesia alters brain synaptic architecture

Wenzel, M.; Leunig, A.; Han, S.; Peterka, D. S.; Yuste, R.

10.1101/862334 — neuroscience — Posted on 2019-12-02

3027 Piriform cortex provides a dominant gamma LFP oscillation in the anterior limbic system

Carmichael, J. E.; Yuen, M. M.; van der Meer, M. A. A.

10.1101/861021 — neuroscience — Posted on 2019-12-02

3028 The Fusiform Gyrus Processes Faces Relative to an Overall Face Average and a Person Average

Shehzad, Z.; Byeon, E.; McCarthy, G.

10.1101/861625 — neuroscience — Posted on 2019-12-02

3029 Conserved and specific genomic features of endogenous polydnaviruses revealed by whole genome sequencing of two ichneumonid wasps

Legeai, F.; Santos, B. F.; Robin, S.; Bretaudeau, A.; Dikow, R. B.; Lemaitre, C.; Jouan, V.; Ravallec, M.; Drezen, J.-M.; Tagu, D.; Gyapay, G.; Zhou, X.; Liu, S.; Webb, B. A.; Brady, S. G.; Volkoff, A.-N.

10.1101/861310 — genomics — Posted on 2019-12-02

3030 Modeling Resistance and Recurrence Patterns of Combined Targeted- Chemoradiotherapy Predicts Benefit of Shorter Induction Period

McClatchy, D. M.; Willers, H.; Hata, A. N.; Piotrowska, Z.; Sequist, L. V.; Paganetti, H.; Grassberger, C.

10.1101/861518 — biophysics — Posted on 2019-12-02

3031 Causal modulation of right fronto-parietal phase synchrony with Transcranial Magnetic Stimulation during a conscious visual detection task

Stengel, C.; Vernet, M.; Amengual, J. L.; Valero-Cabre, A.

10.1101/859330 — neuroscience — Posted on 2019-12-02

3032 Disrupting female flight in the vector Aedes aegypti

O'Leary, S.; Adelman, Z.

10.1101/862300 — genetics — Posted on 2019-12-02

3033 A non-mosaic humanized mouse model of Down syndrome, trisomy of the long arm of human chromosome 21 in mouse chromosome background

Reeves, R. H.; Kazuki, Y.; Gao, F.; Li, Y.; Moyer, A.; Devenney, B.; Hiramatsu, K.; Miyagawa-Tomita, S.; Abe, S.; Kazuki, K.; Kajitani, N.; Uno, N.; Takehara, S.; Takiguchi, M.; Yamakawa, M.; Hasegawa, A.; Shimizu, R.; Matsukura, S.; Noda, N.; Ogonuki, N.; Inoue, K.; Matoba, S.; Ogura, A.; Florea, L. D.; Savonenko, A.; Xiao, M.; Wu, D.; Batista, D.; Yang, J.; Qiu, Z.; Singh, N.; Richstemeier, J.; Takeuchi, T.; Oshimura, M.

10.1101/862433 — genetics — Posted on 2019-12-02

3034 The Geometry and Genetics of Hybridization

Schneemann, H.; De Sanctis, B.; Roze, D.; Bierne, N.; Welch, J. J.

10.1101/862235 — evolutionary biology — Posted on 2019-12-02

3035 TopicNet: a framework for measuring transcriptional regulatory network change

Lou, S.; Li, T.; Kong, X.; Zhang, J.; Liu, J.; Lee, D.; Gerstein, M.

10.1101/862177 — bioinformatics — Posted on 2019-12-02

3036 Auditory enhancement of illusory contour perception

Tivadar, R. I.; Gaglianese, A.; Murray, M. M.

10.1101/860965 — neuroscience — Posted on 2019-12-02

3037 Genetic Underpinnings of Risky Behavior Relate to Altered Neuroanatomy

Aydogan, G.; Daviet, R.; Karlsson Linner, R.; Hare, T. A.; Kable, J. W.; Kranzler, H. R.; Wetherill, R. R.; Ruff, C. C.; Koellinger, P. D.; Nave, G.

10.1101/862417 — neuroscience — Posted on 2019-12-02

3038 Performance Monitoring for Sensorimotor Confidence: A Visuomotor Tracking Study

Locke, S. M.; Mamassian, P.; Landy, M. S.

10.1101/861302 — neuroscience — Posted on 2019-12-02

3039 Development of a highly effective African swine fever virus vaccine by deletion of the I177L gene results in sterile immunity against the current epidemic Eurasia strain

Borca, M. V.; Ramirez-Medina, E.; SiIva, E. B.; Vuono, E. A.; Rai, A.; Pruitt, S.; Holinka, L. G.; Velazquez-Salinas, L.; Zhu, J. J.; Gladue, D. P.

10.1101/861666 — microbiology — Posted on 2019-12-02

3040 Fibroblast Protection of Borrelia burgdorferi from Doxycycline, Cefuroxime and Daptomycin Combination is Eliminated by Oregano or Carvacrol Essential Oil

Bai, C.; Yang, H.; Cui, P.; Quan, R.; Zhang, Y.

10.1101/861575 — microbiology — Posted on 2019-12-02

3041 On generative models of T-cell receptor sequences

Isacchini, G.; Sethna, Z.; Elhanati, Y.; Nourmohammad, A.; Walczak, A. M.; Mora, T.

10.1101/857722 — immunology — Posted on 2019-12-02

3042 SLC2A knockout mice deficient in ascorbic acid synthesis recapitulate aspects of arterial tortuosity syndrome and display mitochondrial respiration defects

Boel, A.; Burger, J.; Vanhomwegen, M.; Beyens, A.; Renard, M.; Barnhoorn, S.; Casteleyn, C.; Reinhardt, D. P.; Descamps, B.; Vanhove, C.; van der Pluijm, I.; Coucke, P.; Willaert, A.; Essers, J.; Callewaert, B.

10.1101/862425 — genetics — Posted on 2019-12-02

3043 Sex enhances survival in Paramecium

Thind, A. S.; Vitali, V.; Guarracino, M. R.; Catania, F.

10.1101/861187 — evolutionary biology — Posted on 2019-12-02

3044 Lizard colour plasticity tracks background seasonal changes

Pellitteri-Rosa, D.; Gazzola, A.; Todisco, S.; Mastropasqua, F.; Liuzzi, C.

10.1101/862268 — evolutionary biology — Posted on 2019-12-02

3045 Biosynthesis of Iron Oxide Nanoparticles via Crocus sativus and their Antifungal Efficacy against Verticillium Wilt Pathogen Verticillium dahliae

Alam, T.; Akbar, F.; Ali, M.; Munis, M. F. H.; Khan, J.

10.1101/861401 — plant biology — Posted on 2019-12-02

3046 Comparative Analysis of In Vitro Responses and Regeneration Between Diverse Bioenergy Sorghum Genotypes

Flinn, B. S.; Dale, S.; Disharoon, A.; Kresovich, S.

10.1101/861328 — plant biology — Posted on 2019-12-02

3047 Control of brown adipose tissue adaptation to nutrient stress by the activin receptor ALK7

Marmol Carrasco, P.; Ibanez, C. F.

10.1101/861609 — physiology — Posted on 2019-12-02

3048 The vagus nerve is necessary for the rapid and widespread neuronal activation in the brain following oral administration of psychoactive bacteria

Bharwani, A.; West, C.; Champagne-Jorgensen, K.; McVey Neufeld, K.-A.; Ruberto, J.; Kunze, W. A.; Bienenstock, J.; Forsythe, P.

10.1101/860890 — neuroscience — Posted on 2019-12-02

3049 Sensory neurons contacting the cerebrospinal fluid require the Reissner fiber to detect spinal curvature in vivo

Orts-Del'Immagine, A.; Cantaut-Belarif, Y.; Thouvenin, O.; Roussel, J.; Baskaran, A.; Langui, D.; Koeth, F.; Bivas, P.; Lejeune, F.-X.; Bardet, P.-L.; Wyart, C.

10.1101/861344 — neuroscience — Posted on 2019-12-02

3050 Enhancer regulation for induced WNT3A expression during neuronal regeneration

Chang, C.-Y.; Hung, J.-H.; Wu, C.-C.; Liang, M.-Z.; Huang, P.-Y.; Li, J.; Chen, H.-I.; Yet, S.-F.; Fung, K. S.; Kao, C.-F.; Chen, L.

10.1101/861153 — molecular biology — Posted on 2019-12-02

3051 A Novel LysR-Type Global Regulator RpvA Controls Persister Formation and Virulence in Staphylococcus aureus

Han, J.; Liu, Z.; Xu, T.; Shi, W.; Xu, X.; Wang, S.; Ji, L.; Xu, Y.; Peng, Q.; Li, W.; Zhang, Y.

10.1101/861500 — microbiology — Posted on 2019-12-02

3052 Construction and Integration of Three De Novo Japanese Human Genome Assemblies toward a Population-Specific Reference

Takayama, J.; Tadaka, S.; Yano, K.; Katsuoka, F.; Gocho, C.; Funayama, T.; Makino, S.; Okamura, Y.; Kikuchi, A.; Kawashima, J.; Otsuki, A.; Yasuda, J.; Kure, S.; Kinoshita, K.; Yamamoto, M.; Tamiya, G.

10.1101/861658 — genomics — Posted on 2019-12-02

3053 AlphaBeta: Computational inference of epimutation rates and spectra from high-throughput DNA methylation data in plants

Shahryary Dizaji, Y.; Symeonidi, A.; Hazarika, R. R.; Denkena, J.; Mubeen, T.; Hofmeister, B.; van Gurp, T.; Colome-Tatche, M.; Verhoeven, K.; Tuskan, G.; Schmitz, R. J.; Johannes, F.

10.1101/862243 — genomics — Posted on 2019-12-02

3054 Found in Space: Nanopore long reads enable the first complete genome assembly of a Malaysian Vibrio parahaemolyticus isolate bearing the pVa plasmid associated with acute hepatopancreatic necrosis disease

Gan, H. M.; Austin, C. M.

10.1101/861476 — genomics — Posted on 2019-12-02

3055 Shuffle-Seq: En masse combinatorial encoding for n-way genetic interaction screens

Dixit, A.; Kuksenko, O.; Feldman, D.; Regev, A.

10.1101/861443 — genomics — Posted on 2019-12-02

3056 Design and analysis of CRISPR-based underdominance toxin-antidote gene drives

Champer, J.; Champer, S. E.; Kim, I.; Clark, A. G.; Messer, P. W.

10.1101/861435 — genetics — Posted on 2019-12-02

3057 Impute.me: an open source, non-profit tool for using data from DTC genetic testing to calculate and interpret polygenic risk scores.

Folkersen, L.; Pain, O.; Ingason, A.; Werge, T.; Lewis, C. M.; Austin, J.

10.1101/861831 — genetics — Posted on 2019-12-02

3058 ACPT gene is inactivated in mammalian lineages that lack enamel and teeth

Mu, Y.; Huang, X.; Liu, R.; Gai, Y.; Liang, N.; Yin, D.; Shan, L.; Xu, S.; Yang, G.

10.1101/861633 — evolutionary biology — Posted on 2019-12-02

3059 Statistically-estimated tree biomass, stem density, and basal area for the upper Midwestern United States at the time of Euro-American settlement

Paciorek, C. J.; Cogbill, C. V.; Peters, J. A.; Goring, S. J.; Williams, J. W.; Mladenoff, D. J.; Dawson, A.; McLachlan, J. S.

10.1101/856526 — ecology — Posted on 2019-12-02

3060 Emergence of a novel immune-evasion strategy from an ancestral protein fold in bacteriophage Mu

Karambelkar, S.; Udupa, S.; Gowthami, V. N.; Ramachandra, S. G.; Swapna, G.; Nagaraja, V.

10.1101/861617 — biochemistry — Posted on 2019-12-02

3061 Schistocephalus parasite infection alters sticklebacks' movement ability and thereby shapes social interactions

Jolles, J. W.; Mazue, G. P. F.; Davidson, J.; Behrmann-Godel, J.; Couzin, I. D.

10.1101/849737 — animal behavior and cognition — Posted on 2019-12-02

3062 Whole genome sequences of 23 species from the Drosophila montium species group (Diptera: Drosophilidae): A resource for testing evolutionary hypotheses

Bronski, M. J.; Martinez, C. C.; Weld, H. A.; Eisen, M. B.

10.1101/861005 — genomics — Posted on 2019-12-02

3063 Chromosome Evolution of Octoploid Strawberry

Hardigan, M. A.; Feldmann, M. J.; Lorant, A.; Famula, R.; Acharya, C.; Cole, G. S.; Edger, P. P.; Knapp, S. J.

10.1101/861526 — genomics — Posted on 2019-12-02

3064 Characterization of the Key Region and Phosphorylation Sites of EcaICE1 for its Molecular Interaction with EcaHOS1 Protein from Eucalyptus camaldulensis

Cheng, L.; Zhang, W.; Hu, J.; Zhang, Z.; Liu, Y.; Lin, Y.

10.1101/861088 — plant biology — Posted on 2019-12-02

3065 Structure-guided molecular grafting of a complex broadly neutralizing viral epitope

Bajic, G.; Maron, M. J.; Tian, M.; Kelsoe, G.; Kuraoka, M.; Schmidt, A. G.

10.1101/860825 — immunology — Posted on 2019-12-02

3066 Comprehensive analysis of lncRNAs reveals candidate prognostic biomarkers in multiple cancer types

Isaev, K.; Jiang, L.; Lee, C. A.; Tsai, R.; Coutinho, F.; Dirks, P. B.; Schramek, D.; Reimand, J.

10.1101/861039 — cancer biology — Posted on 2019-12-02

3067 An optimized acetylcholine sensor for monitoring in vivo cholinergic activity

jing, m.; Li, Y.; Zeng, J.; Huang, P.; Skirzewski, M.; Peng, W.; Qian, T.; Tan, K.; Wu, R.; Zhang, S.; Pan, S.; Xu, M.; Li, H.; Saksida, L. M.; Prado, V. F.; Bussey, T.; Prado, M. A. M.; Chen, L.; Cheng, H.; Li, Y.

10.1101/861690 — neuroscience — Posted on 2019-12-02

3068 Evolution of Salmonella enterica serotype Typhimurium driven by anthropogenic selection and niche adaptation

Bawn, M.; Thilliez, G.; Wheeler, N.; Kirkwood, M.; Petrovska, L.; Dallman, T. J.; Adriaenssens, E. M.; Hall, N.; Kingsley, R. A.

10.1101/804674 — genomics — Posted on 2019-12-02

3069 Paralogs in the PKA regulon traveled different evolutionary routes to divergent expression in budding yeast.

Heineike, B. M.; El-Samad, H.

10.1101/860981 — evolutionary biology — Posted on 2019-12-02

3070 BoxCar Assisted MS Fragmentation (BAMF)

Jenkins, C.; Orsburn, B.

10.1101/860858 — biochemistry — Posted on 2019-12-02

3071 A role of causal inference in non-stationary environments

Shinohara, S.; Manome, N.; Suzuki, K.; Chung, U.-i.; Takahashi, T.; Okamoto, H.; Gunji, Y.; Nakajima, Y.; Mitsuyoshi, S.

10.1101/861096 — animal behavior and cognition — Posted on 2019-12-02

3072 Genomic signature of shifts in selection in a sub-alpine ant and its physiological adaptations

Cicconardi, F.; Krapf, P.; D'Annessa, I.; Gamisch, A.; Wagner, H. C.; Nguyen, A. D.; Economo, E. P.; Mikheyev, A. S.; Guenard, B.; Grabherr, R.; Arthofer, W.; di Marino, D.; Steiner, F.; Schlick-Steiner, B. C.

10.1101/696948 — genomics — Posted on 2019-12-02

3073 The substrate-dependent stereoselectivity of the multicopper oxidase (MCO)-catalyzed oxidative coupling in the biosynthesis of the bisnaphthopyrone viriditoxin

Hu, J.; Flematti, G.; Chooi, Y.-H.

10.1101/846196 — biochemistry — Posted on 2019-12-02

3074 Factors associated with normal linear growth among pre-school children living in better-off households: a multi-country analysis of nationally representative data

Amugsi, D. A.; Dimbuene, Z. T.; Kimani-Murage, E. W.

10.1101/797845 — scientific communication and education — Posted on 2019-12-02

3075 Enhancing senior high school student engagement and academic performance using an inclusive and scalable inquiry-based program

Davenport Huyer, L.; Callaghan, N. I.; Dicks, S.; Scherer, E.; Shukalyuk, A. I.; Jou, M.; Kilkenny, D. M.

10.1101/822783 — scientific communication and education — Posted on 2019-12-02

3076 Signal-space projection suppresses the tACS artifact in EEG recordings

Vosskuhl, J.; Mutanen, T. P.; Neuling, T.; Ilmoniemi, R. J.; Herrmann, C. S.

10.1101/823153 — neuroscience — Posted on 2019-12-02

3077 Sleep homeostasis dynamics reflects temporally integrated local cortical neuronal activity

Thomas, C. W.; Guillaumin, M. C. C.; McKillop, L. E.; Achermann, P.; Vyazovskiy, V. V.

10.1101/756270 — neuroscience — Posted on 2019-12-02

3078 Rewetting of three drained peatlands drives congruent compositional changes in pro- and eukaryotic microbiomes through environmental filtering

Weil, M.; Wang, H.; Bengtsson, M. M.; Jurasinski, G.; Negassa, W.; Couwenberg, J.; Zak, D.; Urich, T.

10.1101/848192 — microbiology — Posted on 2019-12-02

3079 Liquid-like protein interactions catalyze assembly of endocytic vesicles

Day, K. J.; Kago, G.; Wang, L.; Richter, J. B.; Hayden, C. C.; Lafer, E. M.; Stachowiak, J. C.

10.1101/860684 — cell biology — Posted on 2019-12-02

3080 Bacterial diversity in deep-sea sediments under influence of asphalt seep at the Sao Paulo Plateau

Queiroz, L. L.; Bendia, A.; Duarte, R. T. D.; Gracas, D. A. d.; Silva, A. L. d. C. d.; Nakayama, C. R.; Sumida, P. Y.; Lima, A. O. S.; Nagano, Y.; Fujikura, K.; Kitazato, H.; Pellizari, V. H.

10.1101/753616 — microbiology — Posted on 2019-12-02

3081 Subcellular mRNA localization regulates ribosome biogenesis in migrating cells

Dermit, M.; Dodel, M.; Lee, F. C. Y.; Azman, M. S.; Schwenzer, H.; Jones, J. L.; Blagden, S. P.; Ule, J.; Mardakheh, F. K.

10.1101/829739 — cell biology — Posted on 2019-12-02

3082 A universal reporter cell line for bioactivity evaluation of engineered cytokine products

Mock, J. C.; Pellegrino, C. E.; Neri, D.

10.1101/739987 — immunology — Posted on 2019-12-02

3083 Phase separation of Ede1 promotes the initiation of endocytic events

Kozak, M.; Kaksonen, M.

10.1101/861203 — cell biology — Posted on 2019-12-02

3084 The influence of substrate concentration on the culturability of heterotrophic soil microbes isolated by high-throughput dilution-to-extinction cultivation

Bartelme, R.; Custer, J. M.; Dupont, C.; Espinoza, J. L.; Torralba, M.; Khalili, B.; Carini, P.

10.1101/726661 — microbiology — Posted on 2019-12-02

3085 A Halo of Reduced Dinoflagellate Abundances In and Around Eelgrass Beds

Jacobs-Palmer, E.; Gallego, R.; Ramon-Laca, A.; Kunselman, E.; Cribari, K.; Horwith, M.; Kelly, R. P.

10.1101/712612 — ecology — Posted on 2019-12-02

3086 Selectivity Filter Instability Dominates the Low Intrinsic Activity of the TWIK-1 K2P K+ Channel

Nematian-Ardestani, E.; Abd-Wahab, M. F.; Chatelain, F. C.; Sun, H.; Schewe, M.; Baukrowitz, T.; Tucker, S. J.

10.1101/735704 — biophysics — Posted on 2019-12-02

3087 A new approach to crop model calibration: phenotyping plus post-processing.

Casadebaig, P.; Debaeke, P.; Wallach, D.

10.1101/605220 — plant biology — Posted on 2019-12-02

3088 The role of the pre-commissural fornix in episodic autobiographical memory and simulation

Williams, A. N.; Ridgeway, S.; Postans, M.; Graham, K. S.; Lawrence, A. D.; Hodgetts, C. J.

10.1101/706150 — neuroscience — Posted on 2019-12-02

3089 Cdc42EP5/BORG3 modulates SEPT9 to promote actomyosin function and melanoma invasion and metastasis

Farrugia, A. J.; Rodriguez, J.; Orgaz, J. L.; Lucas, M.; Sanz-Moreno, V.; Calvo, F.

10.1101/570747 — cancer biology — Posted on 2019-12-02

3090 Plants emit informative airborne sounds under stress

Khait, I.; Lewin-Epstein, O.; Sharon, R.; Saban, K.; Perelman, R.; Boonman, A.; Yovel, Y.; Hadany, L.

10.1101/507590 — plant biology — Posted on 2019-12-02

3091 Probing Neural Networks for Dynamic Switches of Communication Pathways

Finger, H.; Gast, R.; Gerloff, C.; Engel, A. K.; König, P.

10.1101/523522 — neuroscience — Posted on 2019-12-02

3092 A SMAD1/5-YAP signaling module drives radial glial cell expansion and growth of the developing cerebral cortex

Najas, S.; Pijuan, I.; Esteve-Codina, A.; Usieto, S.; Martinez, J. D.; Zwijsen, A.; Arbones, M. L.; Marti, E.; Le Dreau, G.

10.1101/558486 — developmental biology — Posted on 2019-12-02

3093 Calling Somatic SNVs and Indels with Mutect2

Benjamin, D. I.; Sato, T.; Lichtenstein, L.; Stewart, C.; Getz, G.; Cibulskis, K.

10.1101/861054 — bioinformatics — Posted on 2019-12-02

3094 Self-supervised retinal thickness prediction enables deep learning from unlabeled data to boost classification of diabetic retinopathy

Holmberg, O. G.; Koehler, N. D.; Martins, T.; Siedlecki, J.; Herold, T.; Keidel, L. F.; Asani, B.; Schiefelbein, J.; Priglinger, S.; Kortuem, K.; Theis, F. J.

10.1101/861757 — bioinformatics — Posted on 2019-12-02

3095 Growth-inhibiting activity of citronella essential oil to multiple fungal plant pathogens

Balendres, M. A. O.; Dela Cueva, F. M.

10.1101/860718 — plant biology — Posted on 2019-12-02

3096 MAtCHap: an ultra fast algorithm for solving the single individual haplotype assembly problem.

Magi, A.

10.1101/860262 — bioinformatics — Posted on 2019-12-02

3097 Developing synergistic drug combinations to restore antibiotic sensitivity in drug-resistant Mycobacterium tuberculosis

Omollo, C. O.; Singh, V.; Kigondu, E.; Wasuna, A.; Agarwal, P.; Moosa, A.; Ioerger, T. R.; Mizrahi, V.; Chibale, K.; Warner, D. F.

10.1101/860288 — microbiology — Posted on 2019-12-02

3098 Demand for Multiplatform and Meta-analytic Approaches in Transcriptome Profiling

Tombacz, D.; Torma, G.; Gulyas, G.; Moldovan, N.; Snyder, M.; Boldogkoi, Z.

10.1101/860312 — genomics — Posted on 2019-12-02

3099 How grazing and other disturbance factors influence biodiversity in Cyprus, with a focus on breeding bird communities

Hellicar, M. A.; Kirschel, A. A. N. G.

10.1101/860296 — ecology — Posted on 2019-12-02

3100 Dual-task Interference in a Simulated Driving Environment: Serial or Parallel Processing?

Abbas-Zadeh, M.; Hossein-Zadeh, G.-A.; Vaziri-Pashkam, M.

10.1101/853119 — neuroscience — Posted on 2019-12-02

3101 Infection risk and extensive parental care govern the molecular evolution of Toll-like receptors in birds.

Zhang, Z.; Liang, D.; Chen, G.; Zou, F.; Lei, F.; Dong, L.; Griesser, M.; Liu, Y.

10.1101/860114 — evolutionary biology — Posted on 2019-12-02

3102 Skap2 Regulates Atherosclerosis through Macrophage Polarization and Efferocytosis

Hyatt, D.; Schroeder, A. E.; Bhatnagar, A.; Golan, D. E.; Swanson, K. D.; Alenghat, F. J.

10.1101/857649 — cell biology — Posted on 2019-12-02

3103 Melatonin reduces GSK3β expression and tau phosphorylation via Nrf2 nuclear translocation

Das, R.; Balmik, A. A.; Chinnathambi, S.

10.1101/861229 — cell biology — Posted on 2019-12-02

3104 Effect of Melatonin on Tau aggregation and Tau-mediated cell surface morphology

Das, R.; Balmik, A. A.; Chinnathambi, S.

10.1101/861237 — cell biology — Posted on 2019-12-02

3105 Live analysis and reconstruction of single-particle cryo-electron microscopy data with CryoFLARE

Schenk, A. D.; Cavadini, S.; Thoma, N. H.; Genoud, C.

10.1101/861740 — biophysics — Posted on 2019-12-02

3106 Quantifying subclinical and longitudinal microvascular changes following episcleral plaque brachytherapy (EPB) using spectral-domain OCT angiography.

Green, K. M.; Toy, B. C.; Ashimatey, B. S.; Mustafi, D.; Jennelle, R. L.; Astrahan, M. A.; Chu, Z.; Wang, R. K.; Kim, J.; Berry, J. L.; Kashani, A. H.

10.1101/860148 — scientific communication and education — Posted on 2019-12-02

3107 Glutamine deprivation regulates the origin and function of cancer cell exosomes

Goberdhan, D.; Fan, S.-J.; Kroeger, B.; Marie, P.; Bridges, E.; Mason, J.; McCormick, K.; Zois, C.; Sheldon, H.; Khalid Alham, N.; Johnson, E.; Elis, M.; Stefana, I.; Mendes, C.; Wainwright, M.; Cunningham, C.; Hamdy, F.; Morris, J.; Harris, A. L.; Wilson, C.

10.1101/859447 — cancer biology — Posted on 2019-12-02

3108 Osmotic stress-induced, rapid clustering of IGF2BP proteins nucleates stress granule assembly

Zeng, W.-J.; Lu, C.; Shi, Y.; Chen, X.; Yao, J.

10.1101/846659 — cell biology — Posted on 2019-12-02

3109 Comparative evaluation of Aspergillus niger strains for endogenous pectin depolymerization capacity and suitability for D-galacturonic acid production

Schaefer, D.; Schmitz, K.; Weuster-Botz, D.; Benz, J. P.

10.1101/858548 — bioengineering — Posted on 2019-12-02

3110 Insights from a survey-based analysis of the academic job market

Fernandes, J. D.; Sarabipour, S.; Smith, C. T.; Niemi, N. M.; Jadavji, N. M.; Kozik, A. J.; Holehouse, A. S.; Pejaver, V.; Symmons, O.; Bisson Filho, A. W.; Haage, A.

10.1101/796466 — scientific communication and education — Posted on 2019-12-02

3111 Visual discrimination of optical material properties: a large-scale study

Sawayama, M.; Dobashi, Y.; Okabe, M.; Hosokawa, K.; Koumura, T.; Saarela, T.; Olkkonen, M.; Nishida, S.

10.1101/800870 — neuroscience — Posted on 2019-12-02

3112 TORC1 regulates the transcriptional response to glucose and developmental cycle via the Tap42-Sit4-Rrd1/2 pathway in Saccharomyces cerevisiae

Alfatah, M.; Wong, J. H.; Krishnan, V. G.; Lee, Y. C.; Sin, Q. F.; Goh, C. J. H.; Kong, K. W.; Hoon, S.; Arumugam, P.

10.1101/859793 — genetics — Posted on 2019-12-02

3113 Regional oceanographic features and hydrothermal activity influence protist diversity and biogeography in the Okinawa Trough

Brisbin, M. M.; Conover, A. E.; Mitarai, S.

10.1101/714816 — ecology — Posted on 2019-12-02

3114 Functional Vagotopy in the Cervical Vagus Nerve of the Domestic Pig: Implications for Vagus Nerve Stimulation

10.1101/856989 — neuroscience — Posted on 2019-12-02

3115 Octanol-water partition coefficient measurements for the SAMPL6 Blind Prediction Challenge

Isık, M.; Levorse, D.; Mobley, D. L.; Rhodes, T.; Chodera, J. D.

10.1101/757393 — biophysics — Posted on 2019-12-02

3116 Correction of missing-wedge artifacts in filamentous tomograms by template-based constrained deconvolution

Kovacs, J.; Song, J. H.; Auer, M.; He, J.; Wriggers, W. R.

10.1101/827006 — biophysics — Posted on 2019-12-02

3117 Machine Source Localization of Tursiops Truncatus Whistle-like Sounds in a Reverberant Aquatic Environment

Woodward, S. F.; Reiss, D.; Magnasco, M.

10.1101/606673 — biophysics — Posted on 2019-12-02

3118 BitEpi: A Fast and Accurate Exhaustive Higher-Order Epistasis Search

Bayat, A.; Hosking, B.; Jain, Y.; Hosking, C.; Twine, N.; C. Bauer, D.

10.1101/858282 — bioinformatics — Posted on 2019-12-01

3119 The potential for a released autosomal X-shredder becoming a driving-Y chromosome and invasively suppressing wild populations of malaria mosquitoes

Alcalay, Y.; Fuchs, S.; Galizi, R.; Bernardini, F.; Haghighat-Khah, R. E.; Rusch, D. B.; Adrion, J. R.; Hahn, M. W.; Tortosa, P.; Papathanos, P. A.

10.1101/860551 — genetics — Posted on 2019-12-01

3120 β-cells operate collectively to help maintain glucose homeostasis

Podobnik, B.; Korosak, D.; Skelin Klemen, M.; Stozer, A.; Dolensek, J.; Slak Rupnik, M.; Ivanov, P. C.; Holme, P.; Jusup, M.

10.1101/765933 — biophysics — Posted on 2019-12-01

3121 Heat production in carrion biofilm formed by communally breeding carrion beetles

Matuszewski, S.; Madra-Bielewicz, A.

10.1101/854349 — ecology — Posted on 2019-12-01

3122 Poisson balanced spiking networks

Rullan Buxo, C. E.; Pillow, J. W.

10.1101/836601 — neuroscience — Posted on 2019-12-01

3123 HIV-1 Rev interacts with HERV-K RcREs present in the human genome and promotes export of unspliced HERV-K proviral RNA

Gray, L. R.; Jackson, R. E.; Jackson, P. E. H.; Bekiranov, S. A.; Rekosh, D.; Hammmarskjold, M.-L. A.

10.1101/822619 — cell biology — Posted on 2019-12-01

3124 Numerical cognition based on precise counting with a single spiking neuron.

Rapp, H.; Nawrot, M. P.; Stern, M.

10.1101/662932 — neuroscience — Posted on 2019-12-01

3125 Evidence of multifaceted functions of codon usage in translation within the model beetle Tribolium castaneum

Whittle, C. A.; Kulkarni, A.; Extavour, C. G.

10.1101/754911 — evolutionary biology — Posted on 2019-12-01

3126 A Nodal/Eph signalling relay drives the transition from apical constriction to apico-basal shortening in ascidian endoderm invagination

Fiuza, U.-M.; Negishi, T.; Rouan, A.; Yasuo, H.; Lemaire, P.

10.1101/418988 — developmental biology — Posted on 2019-12-01

3127 The potential for a released autosomal X-shredder becoming a driving-Y chromosome and invasively suppressing wild populations of malaria mosquitoes

Alcalay, Y.; Fuchs, S.; Galizi, R.; Bernardini, F.; Haghighat-Khah, R. E.; Rusch, D. B.; Adrion, J. R.; Hahn, M. W.; Tortosa, P.; Papathanos, P. A.

10.1101/860551 — genetics — Posted on 2019-12-01

3128 Longitudinal cell division is associated with single mutations in the FtsZ-recruiting SsgB in Streptomyces

Xiao, X.; Willemse, J.; Voskamp, P.; Li, X.; Lamers, M. H.; Abrahams, J. P.; Pannu, N.; van Wezel, G. P.

10.1101/860916 — developmental biology — Posted on 2019-12-01

Han, Y.; Sichterman, B.; Carrillo, M.; Gazzola, V.; Keysers, C.

10.1101/857094 — animal behavior and cognition — Posted on 2019-12-01

3130 Characterization of transcription activation domain of EcaICE1 and its interaction with EcaSIZ1 in Eucalyptus camaldulensis

Zhang, Z.; Cheng, L.; Zhang, W.; Hu, J.; Liu, Y.; Lin, Y.

10.1101/859819 — plant biology — Posted on 2019-12-01

3131 Comprehensive post mortem brain samples analysis detects global reduction of multiple proteasome subunits expression in schizophrenia

Hertzberg, L.; Maggio, N.; Muler, I.; Yitzhaky, A.; Majer, M.; Haroutunian, V.; Katsel, P.; Domany, E.; Weiser, M.

10.1101/853226 — neuroscience — Posted on 2019-12-01

3132 Perceptual Invariance of Words and Other Learned Sounds in Non-human Primates

Melchor, J.; Moran, I.; Figueroa, T.; Lemus, L.

10.1101/805218 — neuroscience — Posted on 2019-12-01

3133 State and trait characteristics of anterior insula time-varying functional connectivity

Pasquini, L.; Toller, G.; Staffaroni, A.; Brown, J. A.; Deng, J.; Lee, A.; Kurcyus, K.; Shdo, S. M.; Allen, I.; Sturm, V. E.; Cobigo, Y.; Borghesani, V.; Battistella, G.; Gorno-Tempini, M. L.; Rankin, K. P.; Kramer, J.; Rosen, H. H.; Miller, B. L.; Seeley, W. W.

10.1101/716720 — neuroscience — Posted on 2019-12-01

3134 A smart polymer for sequence-selective binding, pulldown and release of DNA targets

Krieg, E.; Gupta, K.; Dahl, A.; Lesche, M.; Boye, S.; Lederer, A.; Shih, W. M.

10.1101/573030 — molecular biology — Posted on 2019-12-01

3135 Structural basis of RNA Polymerase III transcription repression by Maf1

Vorländer, M. K.; Baudin, F.; Moir, R. D.; Wetzel, R.; Hagen, W. J. H.; Willis, I. M.; Müller, C. W.

10.1101/859132 — molecular biology — Posted on 2019-12-01

3136 Identifying Operons with Deep Neural Networks

Assaf, R.; Xia, F.; Stevens, R.

10.1101/860221 — bioinformatics — Posted on 2019-12-01

3137 TNFPred: Identifying tumor necrosis factors using hybrid features based on word embeddings

Nguyen, T.-T.-D.; Le, N.-Q.-K.; Ho, Q.-T.; Phan, D.-V.; Ou, Y.-Y.

10.1101/860791 — bioinformatics — Posted on 2019-12-01

3138 Food supplementation affects gut microbiota and immunological resistance to parasites in a wild bird species

Knutie, S. A.

10.1101/770644 — ecology — Posted on 2019-12-01

3139 Effects of temperature on Zika dynamics and control

Ngonghala, C. N.; Ryan, S. J.; Tesla, B.; Demokovsky, L. R.; Mordecai, E. A.; Murdock, C. C.; Bonds, M. H.

10.1101/855072 — ecology — Posted on 2019-12-01

3140 An interactive retrieval system for clinical trial studies with context-dependent protocol elements

Park, J.; Kim, K.; Park, S.; Hwang, W.; Yoo, S.; Yi, G.; Lee, D.

10.1101/814996 — bioinformatics — Posted on 2019-12-01

3141 Elucidating the competition between heterotrophic denitrification and DNRA using the resource-ratio theory

Jia, M.; Winkler, M. K. H.; Volcke, E. I. P.

10.1101/852327 — microbiology — Posted on 2019-12-01

3142 Single AAV-mediated mutation replacement genome editing in limited number of photoreceptors mediate marked visual restoration

NISHIGUCHI, K. M.; Fujita, K.; Miya, F.; Katayama, S.; Nakazawa, T.

10.1101/552653 — bioengineering — Posted on 2019-12-01

3143 Topologically Dependent Abundance of Spontaneous DNA Damage in Single Human Cells

Zhu, Q.; Niu, Y.; Gundry, M.; Sheng, K.; Niu, M.; Zong, C.

10.1101/859686 — genomics — Posted on 2019-12-01

3144 Systematic detection of Mendelian and non-Mendelian variants associated with retinitis pigmentosa by genome-wide association study

Nishiguchi, K. M.; Miya, F.; Fujita, K.; Akiyama, M.; Mori, Y.; Kamatani, T.; Koyanagi, Y.; Sato, K.; Takigawa, T.; Ueno, S.; Tsugita, M.; Kunikata, H.; Cisarova, K.; Nishino, J.; Murakami, A.; Abe, T.; Momozawa, Y.; Terasaki, H.; Wada, Y.; Sonoda, K.-H.; Rivolta, C.; Ishibashi, T.; Tsunoda, T.; Tsujikawa, M.; Ikeda, Y.; Nakazawa, T.