date is 2024-02
Select an archive month  
May 2025
April 2025
March 2025
February 2025
January 2025
December 2024
November 2024
October 2024
September 2024
August 2024
July 2024
June 2024
May 2024
April 2024
March 2024
February 2024
January 2024
December 2023
November 2023
October 2023
September 2023
August 2023
July 2023
June 2023
May 2023
April 2023
March 2023
February 2023
January 2023
December 2022
November 2022
October 2022
September 2022
August 2022
July 2022
June 2022
May 2022
April 2022
March 2022
February 2022
January 2022
December 2021
November 2021
October 2021
September 2021
August 2021
July 2021
June 2021
May 2021
April 2021
March 2021
February 2021
January 2021
December 2020
November 2020
October 2020
September 2020
August 2020
July 2020
June 2020
May 2020
April 2020
March 2020
February 2020
January 2020
December 2019
November 2019
October 2019
September 2019
August 2019
July 2019
June 2019
May 2019
April 2019
March 2019
February 2019
January 2019
December 2018
November 2018
October 2018
September 2018
August 2018
July 2018
June 2018
May 2018
April 2018
March 2018
February 2018
January 2018
December 2017
November 2017
October 2017
September 2017
August 2017
July 2017
June 2017
May 2017
April 2017
March 2017
February 2017
January 2017
December 2016
November 2016
October 2016
September 2016
August 2016
July 2016
June 2016
May 2016
April 2016
March 2016
February 2016
January 2016
December 2015
November 2015
October 2015
September 2015
August 2015
July 2015
June 2015
May 2015
April 2015
March 2015
February 2015
January 2015
December 2014
November 2014
October 2014
September 2014
August 2014
July 2014
June 2014
May 2014
April 2014
March 2014
February 2014
January 2014
December 2013
November 2013

Archive, 2024-02

2 Domain coupling in activation of a family C GPCR
Latorraca, N. R.; Sabaat, S.; Habrian, C.; Bleier, J.; Stanley, C.; Marqusee, S.; Isacoff, E. Y.
10.1101/2024.02.28.582567 — biophysics — Posted on 2024-02-29
3 Multimodal intrinsic activation of GPCRs in ultrastable plasma membrane nanodomains
Kockelkoren, G.; Carstensen, J.; Lauritsen, L.; Kazepidou, E.; Tonnesen, A.; Shuttle, C. G.; Kaas, P. S.; Gupta, A.; Breuer, A.; Rasmussen, S. G. F.; Duffet, L.; Warne, T.; Patriarchi, T.; Tate, C. G.; Uline, M.; Stamou, D.
10.1101/2024.02.28.582451 — biophysics — Posted on 2024-02-29
4 Study of Impacts of Two Types of Cellular Aging on the Yeast Bud Morphogenesis
Tsai, K.; Zhou, Z.; Yang, J.; Xu, Z.; Xu, S.; Zandi, R.; Hao, N.; Chen, W.; Alber, M.
10.1101/2024.02.29.582376 — biophysics — Posted on 2024-02-29
6 Phosphate-binding pocket on cyclin B governs CDK substrate phosphorylation and mitotic timing
Ng, H. Y.; Adly, A. N.; Whelpley, D. H.; Suhandynata, R. T.; Zhou, H.; Morgan, D. O.
10.1101/2024.02.28.582599 — biochemistry — Posted on 2024-02-29
9 β-Hydroxybutyrate promotes basal insulin secretion while decreasing glucagon secretion in mouse and human islets.
Banerjee, R.; Zhu, Y.; Brownrigg, G. P.; Moravcova, R.; Rogalski, J. C.; Foster, L.; Johnson, J. D.; Kolic, J.
10.1101/2024.02.27.582117 — cell biology — Posted on 2024-02-29
11 A single-cell atlas of the murine pancreatic ductal tree identifies novel cell populations with potential implications in pancreas regeneration and exocrine pathogenesis.
Fernandez, A.; Casamitjana, J.; Holguin-Horcajo, A.; Coolens, K.; Mularoni, L.; Pasquali, L.; Bailey-Lundberg, J. M.; Rooman, I.; Wang, Y. J.; Rovira, M.
10.1101/2024.02.26.582044 — cell biology — Posted on 2024-02-29
12 Endothelial features along the pulmonary vascular tree in chronic thromboembolic pulmonary hypertension: distinctive or shared facets?
Verhaegen, J.; Willems, L.; Wagenaar, A.; Spreuwers, R.; Dahdah, N.; Aversa, L.; Verbelen, T.; Delcroix, M.; Quarck, R.
10.1101/2024.02.27.582290 — cell biology — Posted on 2024-02-29
14 Atlastin-1 regulates endosomal tubulation and lysosomal proteolysis in human cortical neurons
Zlamalova, E.; Rodger, C.; Greco, F.; Kleniuk, J.; Nadadur, A. G.; Kadlecova, Z.; Reid, E.
10.1101/2024.02.29.582512 — cell biology — Posted on 2024-02-29
15 FHOD-1/profilin-mediated actin assembly protect sarcomeres against contraction-induced deformation in C. elegans
Kimmich, M. D.; Sundaramurthy, S.; Geary, M. A.; Lesanpezeshki, L.; Yingling, C. V.; Vanapalli, S. A.; Littlefield, R. S.; Pruyne, D.
10.1101/2024.02.29.582848 — cell biology — Posted on 2024-02-29
16 Glomerular Elasticity and Gene Expression Patterns Define Two Phases of Alport Nephropathy
Yoon, J.; Liu, Z.; Alaba, M.; Bruggeman, L. A.; Janmey, P.; Arana, C.; Ayenuyo, O.; Medeiros, I.; Eddy, S.; Kretzler, M.; Henderson, J. M.; Naik, A.; Chang, A. N.; Miller, R. T.
10.1101/2024.02.26.582201 — cell biology — Posted on 2024-02-29
17 Metabolic and age-associated epigenetic barriers during direct reprogramming of mouse fibroblasts into induced cardiomyocytes
Santos, F.; Correia, M.; Dias, R.; Bola, B.; Noberini, R.; Ferreira, R. S.; Domingues, P.; Teixeira, J.; Bonaldi, T.; Oliveira, P. J.; Bernardes de Jesus, B.; Bar, C.; Nobrega-Pereira, S.
10.1101/2024.02.28.582570 — cell biology — Posted on 2024-02-29
19 An injury-induced tissue niche shaped by mesenchymal plasticity coordinates the regenerative and disease response in the lung
Jones, D. L.; Morley, M. P.; Li, X.; Yun, Y.; Cardenas-Diaz, F. L.; Li, S.; Zhou, S.; Schaefer, S. E.; Chembazhi, U. V.; Nottingham, A.; Lin, S.; Cantu, E.; Diamond, J. M.; Basil, M. C.; Vaughan, A. E.; Morrisey, E. E.
10.1101/2024.02.26.582147 — cell biology — Posted on 2024-02-29
21 Doublecortin reinforces microtubules to promote growth cone advance in soft environments
Dema, A.; Charafeddine, R. A.; van Haren, J.; Rahgozar, S.; Viola, G.; Jacobs, K. A.; Kutys, M. L.; Wittmann, T.
10.1101/2024.02.28.582626 — cell biology — Posted on 2024-02-29
22 Comparison of monomeric variants of StayGold
Miyawaki, A.; Shimozono, S.; Ando, R.; Sugiyama, M.; Hirano, M.; Niino, Y.
10.1101/2024.02.28.582207 — bioengineering — Posted on 2024-02-29
23 DELE1 promotes translation-associated homeostasis, growth, and survival in mitochondrial myopathy
Lin, H.-P.; Petersen, J. D.; Gilsrud, A.; Madruga, A.; D'Silva, T. M.; Huang, X.; Shammas, M. K.; Randolph, N. P.; Li, Y.; Jones, D. R.; Pacold, M. E.; Narendra, D.
10.1101/2024.02.29.582673 — cell biology — Posted on 2024-02-29
24 SUMO Promotes DNA Repair Protein Collaboration to Support Alterative Telomere Lengthening in the Absence of PML
Zhao, R.; Xu, M.; Wondisford, A. R.; Lackner, R. M.; Salsman, J.; Dellaire, G.; Chenoweth, D. M.; O'Sullivan, R. J.; Zhao, X.; Zhang, H.
10.1101/2024.02.29.582813 — cell biology — Posted on 2024-02-29
26 Pulses of Class I PI3kinase activity identify the release and recapture of prey from neutrophil phagosomes
Muir, C. F.; Reyes-Aldasoro, C. C.; Ellett, F.; Prajsnar, T.; Ho, Y. X.; Bernut, A.; Loynes, C. A.; Elworthy, S.; Bowden, K. A.; Cadby, A. J.; Prince, L.; King, J. S.; Condliffe, A. M.; Renshaw, S.
10.1101/2024.02.29.582694 — cell biology — Posted on 2024-02-29
29 Limited Cell-Autonomous Anticancer Mechanisms in Long-Lived Bats
Athar, F.; Zheng, Z.; Riquier, S.; Zacher, M.; Alcock, D.; Galazyuk, A.; Cooper, L. N.; Schountz, T.; Wang, L.; Teeling, E.; Seluanov, A.; Gorbunova, V.
10.1101/2024.02.29.582714 — cell biology — Posted on 2024-02-29
32 Multiple triggers converge to preferential effector coupling in the CB2R through a complex allosteric communication network
Morales-Pastor, A.; Miljus, T.; Stepniewski, T. M.; Ledesma, V.; Heydenreich, F.; Flock, T.; Plouffe, B.; Le Gouill, C.; Duchaine, J.; Guba, W.; Rufer, A.; Grether, U.; Bouvier, M.; Veprintsev, D.; Selent, J.
10.1101/2024.02.27.582279 — cell biology — Posted on 2024-02-29
33 Insights into post-translational regulation of skeletal muscle contractile function by the acetyltransferases, p300 and CBP
Meyer, G.; Ferey, J. L. A.; Sanford, J. A.; Fitzgerald, L. S.; Greenberg, A. E.; Svensson, K.; Greenberg, M. J.; Schenk, S.
10.1101/2024.02.27.582179 — cell biology — Posted on 2024-02-29
34 Thymidine Phosphorylase Promotes the Formation of Abdominal Aortic Aneurysm in Mice Fed a Western Diet
Hong, L.; Yue, H.; Cai, D.; DeHart, A.; Toloza-Alvarez, G.; Du, L.; Zhou, X.; Fan, X.; Huang, H.; Chen, S.-Y.; Rahaman, S.; Zhuang, J.; Li, W.
10.1101/2024.02.27.582208 — cell biology — Posted on 2024-02-29
39 Chemical tools to expand the ligandable proteome: diversity-oriented synthesis-based photoreactive stereoprobes
Ogasawara, D.; Konrad, D.; Tan, Z. Y.; Carey, K.; Luo, J.; Won, S. J.; Li, H.; Carter, T.; DeMeester, K.; Njomen, E.; Schreiber, S.; Xavier, R.; Melillo, B.; Cravatt, B.
10.1101/2024.02.27.582206 — biochemistry — Posted on 2024-02-29
43 Dynamics of RNA localization to nuclear speckles are connected to splicing efficiency
Wu, J.; Xiao, Y.; Liu, Y.; Wen, L.; Jin, C.; Liu, S.; Paul, S.; He, C.; Regev, O.; Fei, J.
10.1101/2024.02.29.581881 — cell biology — Posted on 2024-02-29
44 Structural basis of the allosteric regulation of cyanobacterial glucose-6-phosphate dehydrogenase by the redox sensor OpcA
Doello, S.; Shvarev, D.; Theune, M. L.; Sauerwein, J.; Klon, A.; Keskin, E.; Boehm, M.; Gutekunst, K.; Forchhammer, K.
10.1101/2024.02.29.582749 — molecular biology — Posted on 2024-02-29
46 Spatio-temporal dynamics of cyanobacterium Dolichospermum lemmermannii populations in a bloom-prone region of Lake Superior
Wood, A.; Callaghan, J. D.; Loiselle, R.; McManus, R. M.; Brovold, S. S.; Wellard Kelly, H. A.; Alexson, E. E.; Sterner, R. W.; Hudson, M. J.; Sheik, C. S.
10.1101/2024.02.28.582538 — microbiology — Posted on 2024-02-29
47 High-Resolution Spatial Transcriptomic Atlas of Mouse Soleus Muscle: Unveiling Single Cell and Subcellular Heterogeneity in Health and Denervation
Hsu, J.-E.; Ruiz, L.; Hwang, Y.; Guzman, S.; Cho, C.-S.; Cheng, W.; Si, Y.; Macpherson, P.; Schrank, M.; Jun, G.; Kang, H.-M.; Kim, M.; Brooks, S.; Lee, J. H.
10.1101/2024.02.26.582103 — physiology — Posted on 2024-02-29
49 Proteomic Characterization of Intrahepatic Cholangiocarcinoma Identifies Distinct Subgroups and Proteins Associated with Time-To-Recurrence
Werner, T.; Budau, K.-L.; Cosenza Contreras, M.; Hause, F.; Kurowski, K.; Pinter, N.; Schueler, J.; Werner, M.; Sigel, C.; Tang, L.; Bronsert, P.; Schilling, O.
10.1101/2024.02.28.582093 — cancer biology — Posted on 2024-02-29
53 Genome-wide association study reveals multiple loci for analgesia and heroin taking behavior in outbred rats
Kuhn, B. N.; Cannella, N. N.; Sanchez, T.; Peng, B.; Polesskaya, O.; Gupta, A.; Solberg-Woods, L.; Chung, D.; Ciccocioppo, R.; Kalivas, P.; Palmer, A. A.
10.1101/2024.02.27.582340 — genetics — Posted on 2024-02-29
54 The Interplay of Ecological Opportunity and Adult Foraging Strategies in Juvenile Sparrow Individual Specialization
Ricote, N.; Weinberger, C.; Ramirez-Otarola, N.; Bustamante, S.; Malaga, M. L.; Barcelo, G.; Sabat, P.; Newsome, S. D.; Maldonado, K.
10.1101/2024.02.29.582146 — ecology — Posted on 2024-02-29
55 Conserved helical motifs in the Ikaros IDR mediate NuRD interaction and transcriptional repression
Zhang, T.; Wang, Y.-F.; Montoya, A.; Nebioglu, N.; Pallikonda, H. A.; Georgieva, R.; Patrascan, I.; King, J. W.; Kramer, H. B.; Shliaha, P. V.; Rueda, D. S.; Merkenschlager, M.
10.1101/2024.02.29.582782 — molecular biology — Posted on 2024-02-29
57 Endometriotic lesions exhibit distinct metabolic signature compared to paired eutopic endometrium at the single-cell level
Sarsenova, M.; Lawarde, A.; Pathare, A.; Saare, M.; Modhukur, V.; Soplepmann, P.; Terasmaa, A.; Kaambre, T.; Gemzell-Danielsson, K.; Lalitkumar, P. G. L.; Salumets, A.; Peters, M.
10.1101/2024.02.27.580606 — molecular biology — Posted on 2024-02-29
59 Neuronal ARHGAP8 controls synapse structure and AMPA receptor-mediated synaptic transmission
Schmidt, J.; Inacio, A.; Ferreira, J. S.; Serrenho, D.; Socodato, R.; Beltrao, N.; Ribeiro, L. F.; Pinheiro, P.; Relvas, J. B.; Carvalho, A. L.
10.1101/2024.02.29.582472 — neuroscience — Posted on 2024-02-29
63 High-accuracy crRNA array assembly strategy for multiplex CRISPR
Zhao, X.; Yang, L.; Li, P.; Cheng, Z.; Jia, Y.; Luo, L.; Bi, A.; Xiong, H.; Zhang, H.; Zhang, J.; Zhang, Y.
10.1101/2024.02.27.582417 — synthetic biology — Posted on 2024-02-29
66 Statistical design of a synthetic microbiome that clears a multi-drug resistant gut pathogen
Oliveira, R.; Pandey, B.; Lee, K.; Yousef, M.; Chen, R. Y.; Triebold, C.; McSpadden, E.; Haro, F.; Aksianiuk, V.; Ramanujam, R.; Kuehn, S.; Raman, A.
10.1101/2024.02.28.582635 — synthetic biology — Posted on 2024-02-29
67 Genome-Wide Association Study Reveals Influence of Cell-specific Gene Networks on Soybean Root System Architecture
Sun, Y.; Miler, C.; Rajurkar, A.; Lynch, R.; Aylward, A.; Zhang, L.; Shaner, M.; Copeland, C.; Ye, H.; Nguyen, H. T.; Busch, W.; Michael, T. P.
10.1101/2024.02.27.581071 — plant biology — Posted on 2024-02-29
70 Detecting Genetic Interactions with Visible Neural Networks
van Hilten, A.; Melograna, F.; Fan, B.; Niessen, W. J.; van Steen, K.; Roshchupkin, G. V.
10.1101/2024.02.27.582086 — bioinformatics — Posted on 2024-02-29
72 Three-dimensional flow assessment of microvascular beds with interstitial space
Rajeeva Pandian, N. K.; Farell, A. M.; Davis, E. E.; Sundaram, S.; Teo, J. L. C.; Eyckmans, J.; Chen, C. S.
10.1101/2024.02.28.582152 — bioengineering — Posted on 2024-02-29
73 Intracellular biomacromolecule delivery by stimuli responsive protein vesicles loaded by hydrophobic ion pairing
Gray, M. A.; de Janon, A.; Seeler, M.; Heller, W. T.; Panoskaltsis, N.; Mantalaris, A.; Champion, J. A.
10.1101/2024.02.27.582187 — bioengineering — Posted on 2024-02-29
75 Targeting Tuberculosis: Novel Scaffolds for Inhibiting Cytochrome bd Oxidase
Seitz, C.; Ahn, S.-H.; Wei, H.; Kyte, M.; Cook, G.; Krausd, K.; McCammon, J. A.
10.1101/2024.02.28.582612 — biochemistry — Posted on 2024-02-29
76 Codon Pair-Specific Translation Defects Trigger Ribosome-Associated Quality Control to Avoid Proteotoxic Stress
Wu, J.; Eggers, C.; Sin, O.; Koziej, L.; Mancilla, H.; Mollet, F.; Scholer, H. R.; Drexler, H. C.; Ranff, T.; Fufezan, C.; Kraft, C.; Glatt, S.; Bruder, J. M.; Leidel, S. A.
10.1101/2024.02.27.582385 — biochemistry — Posted on 2024-02-29
79 Whole genome sequencing of four Ixodes species expands understanding of tick evolution
Cerqueira de Araujo, A.; Noel, B.; Bretaudeau, A.; Labadie, K.; Boudet, M.; Tadrent, N.; Istace, B.; Kritli, S.; Cruaud, C.; Olaso, R.; Deleuze, J.-F.; Voordouw, M.; Hervet, C.; Plantard, O.; Zamoto-Niikura, A.; Chertemps, T.; Maibeche, M.; Hilliou, F.; Le Goff, G.; Kopacek, P.; Perner, J.; Chmelar, J.; Mazak, V.; Jmel, M. A.; Kotsyfakis, M.; Medina, J. M.; Hackenberg, M.; Simo, L.; Wincker, P.; Aury, J.-M.; Rispe, C.
10.1101/2024.02.29.581698 — genomics — Posted on 2024-02-29
81 A SNP-based honey bee paternity assignment test for evaluating the effectiveness of mating stations and its application to the Ataun valley, Basque Country, Spain
Parejo, M.; Galartza, E.; Momeni, J.; Gorrochategui-Ortega, J.; Farajzadeh, L.; Wegener, J.; Bienefeld, K.; Zarraonaindia, I.; Estonba, A.
10.1101/2024.02.27.580467 — genetics — Posted on 2024-02-29
84 Functional overlap between the mammalian SAR1A and SAR1B paralogs in vivo
Tang, V. T.; Xiang, J.; Chen, Z.; McCormick, J.; Abbineni, P.; Chen, X.-W.; Hoenerhoff, M.; Emmer, B. T.; Khoriaty, R.; Lin, J. D.; Ginsburg, D.
10.1101/2024.02.27.582310 — genetics — Posted on 2024-02-29
85 Taste evolution in an herbivorous drosophilid
Pelaez, J. N.; Bernstein, S. N.; Okoro, J.; Rodas, E.; Liang, I.; Leipertz, A.; Marion-Poll, F.; Whiteman, N. K.
10.1101/2024.02.27.582299 — evolutionary biology — Posted on 2024-02-29
86 Nicotinamide riboside activates renal metabolism and protects the kidney in a model of Alport syndrome
Jones, B. A.; Gisch, D. L.; Myakala, K.; Sadiq, A.; Cheng, Y.-H.; Taranenko, E.; Panov, J.; Korolowicz, K.; Wang, X.; Rosenberg, A. Z.; Jain, S.; Eadon, M. T.; Levi, M.
10.1101/2024.02.26.580911 — molecular biology — Posted on 2024-02-29
90 Discovery of anti-SARS-CoV-2 S2 protein antibody CV804 with broad-spectrum reactivity with various beta coronaviruses and analysis of its pharmacological properties in vitro and in vivo
Tsugawa, Y.; Furukawa, K.; Ise, T.; Takayama, M.; Ota, T.; Kuroda, T.; Shano, S.; Hashimoto, T.; Konishi, H.; Ishihara, T.; Sato, M.; Kamada, H.; Fukao, K.; Shishido, T.; Takahashi, T.; Nagata, S.
10.1101/2024.02.28.582480 — microbiology — Posted on 2024-02-29
91 Glycerol degradation in the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius involves an unusual glycerol-3-phosphate dehydrogenase
Schmerling, C.; Schroeder, C.; Zhou, X.; Busche, T.; Kalinowski, J.; Montero, L.; Schmitz, O.; Kaschani, F.; Ninck, S.; Kaiser, M.; Bost, J.; Recalde, A.; Albers, S.-V.; Siebers, B.; Braesen, C.
10.1101/2024.02.29.582781 — microbiology — Posted on 2024-02-29
93 Distinct Escherichia coli transcriptional profiles in the guts of recurrent UTI sufferers revealed by pan-genome hybrid selection
Young, M. G.; Straub, T. J.; Worby, C. J.; Metsky, H. C.; Gnirke, A.; Bronson, R. A.; van Dijk, L. R.; Desjardins, C. A.; Matranga, C.; Qu, J.; Dodson, K.; Schreiber, H. L.; Manson, A. L.; Hultgren, S. J.; Earl, A. M.
10.1101/2024.02.29.582780 — microbiology — Posted on 2024-02-29
95 Protective effect and molecular mechanisms of human non-neutralizing cross-reactive spike antibodies elicited by SARS-CoV-2 mRNA vaccination
Clark, J.; Hoxie, I.; Adelsberg, D.; Sapse, I.; Andreata-Santos, R.; Yong, J.; Amanat, F.; Tcheou, J.; Raskin, A.; Singh, G.; Gonzalez-Dominguez, I.; Edgar, J.; Bournazos, S.; Sun, W.; Carreno, J. M.; Simon, V.; Ellebedy, A.; Krammer, F.
10.1101/2024.02.28.582613 — immunology — Posted on 2024-02-29
96 Treponema pallidum periplasmic and membrane proteins are recognized by circulating and skin CD4+ T cells
Reid, T. B.; Godornes, C.; Campbell, V. L.; Laing, K. J.; Tantalo, L. C.; Gomez, A.; Pholsena, T. N.; Lieberman, N. A. P.; Krause, T. M.; Cegielski, V. I.; Culver, L. A.; Nguyen, N.; Tong, D. Q.; Hawley, K. L.; Greninger, A. L.; Giacani, L.; Cameron, C. E.; Dombrowski, J. C.; Wald, A.; Koelle, D. M.
10.1101/2024.02.27.581790 — immunology — Posted on 2024-02-29
99 A general strategy to engineer high-performance mammalian Whole-Cell Biosensors
di Bernardo, D.; Mallozzi, A.; Fusco, V.; Ragazzini, F.; Praznik, A.; Jerala, R.
10.1101/2024.02.28.582526 — synthetic biology — Posted on 2024-02-29
101 Peptide Mold: A Novel Strategy for Mapping Potential Binding Sites in Protein Targets
Bagwe, P. B.; Jagtap, Y.; Ghegade, V.; Machhar, J. S.; Martis, E.; Joshi, S. V.; Kharkar, P. S.
10.1101/2024.02.28.582665 — bioinformatics — Posted on 2024-02-29
103 Hachiman is a genome integrity sensor
Tuck, O. T.; Adler, B. A.; Armbruster, E. G.; Lahiri, A.; Hu, J. J.; Zhou, J.; Pogliano, J.; Doudna, J. A.
10.1101/2024.02.29.582594 — biochemistry — Posted on 2024-02-29
109 Curcumin and turmeric extract inhibit SARS-CoV-2 pseudovirus cell entry and Spike mediated cell fusion
Septisetyani, E. P. P.; Lestari, D.; Paramitasari, K. A.; Prasetyaningrum, P. W.; Kastian, R. F.; Anam, K.; Santoso, A.; Eriani, K.
10.1101/2023.09.28.560070 — pharmacology and toxicology — Posted on 2024-02-29
112 Bicyclic pyrrolidine inhibitors of Toxoplasma gondii phenylalanine t-RNA synthetase with antiparasitic potency in vitro and brain exposure
Ence, C. C.; Uddin, T.; Borrel, J.; Mittal, P.; Xie, H.; Zoller, J.; Sharma, A.; Comer, E.; Schreiber, S. L.; Melillo, B.; Sibley, L. D.; Chatterjee, A. K.
10.1101/2024.02.28.582607 — microbiology — Posted on 2024-02-29
115 Syngap1 regulates the synaptic drive and membrane excitability of Parvalbumin-positive interneurons in mouse auditory cortex
Francavilla, R.; Chattopadhyaya, B.; Damo Kamda, J. L.; Jadhav, V.; Kourrich, S.; Michaud, J. L.; Di Cristo, G.
10.1101/2024.02.27.582362 — neuroscience — Posted on 2024-02-29
116 Blood metabolomic profiling reveals new targets in the management of psychological symptoms associated with alcohol use disorder
Leclercq, S.; Ahmed, H.; Amadieu, C.; Petit, G.; Koistinen, V.; Leyrolle, Q.; Poncin, M.; Stärkel, P.; Kok, E.; Karhunen, P. J.; de Timary, P.; Laye, S.; Neyrinck, A. M.; Kärkkäinen, O. K.; Hanhineva, K.; Delzenne, N.
10.1101/2024.02.27.582239 — neuroscience — Posted on 2024-02-29
117 WITHDRAWN: The adhesion GPCR Adgrd1 is a prion protein receptor and a mediator of prion cytotoxicity
Lakkaraju, A. K.; Tejero, O.; Guixa-Gonzalez, R.; De Cecco, E.; Jungo, M.; Tsai, C.-J.; Mastromartino, R.; Marino, J.; Deupi, X.; Hornemann, S.; Schertler, G. F. X.; Aguzzi, A.
10.1101/2023.04.29.538801 — neuroscience — Posted on 2024-02-29
118 Single Testicular Biopsy: Changes in the vascular architecture of the tunica albuginea
Oliveira Filho, A. B. d.; Peruquetti, R.; Rasmussen, L. T.; Cesar, M. T.; Centola, C. A. P.; Cedenho, A. P.
10.1101/2024.02.26.582049 — pathology — Posted on 2024-02-29
119 Pharmacodynamic evaluation of AUM001/tinodasertib, an oral inhibitor of mitogen-activated protein kinase (MAPK)-interacting protein kinase 1, 2 (MNK1/2) in preclinical models and tissues from a Phase 1 clinical study
Gan, B. H.; Lee, L. H.; Takeda, R.; Yasin, M.; Teneggi, V.; Ethirajulu, K.; Yeo, P.; Umrani, D.; Pendharkar, V.; Lim, D. W. T.; Li, G.; Lu, Q.; Cao, Y.; Nellore, R.; Blanchard, S.; HENTZE, H.; Novotny-Diermayr, V.
10.1101/2024.02.23.581717 — cancer biology — Posted on 2024-02-29
120 A Lung Cancer Mouse Model Database
Cai, L.; Gao, Y.; DeBerardinis, R. J.; Chen, T.; Winslow, M. M.; Xiao, G.; Rudin, C.; Oliver, T. G.; Minna, J. D.; Xie, Y.
10.1101/2024.02.28.582577 — cancer biology — Posted on 2024-02-29
123 Diplopoda in the world fossil record
Alvarez Rodriguez, M.; Riquelme, F.; Patricio, M. A. H.; Cupul-Magana, F.
10.1101/2024.02.21.581465 — paleontology — Posted on 2024-02-29
124 Vaccination generates functional progenitor tumor-specific CD8 T cells and long-term tumor control
Detres Roman, C. R.; Rudloff, M. W.; Revetta, F.; Favret, N. R.; Murray, K. A.; Roetman, J. J.; Erwin, M. M.; Washington, M. K.; Philip, M.
10.1101/2024.02.26.582064 — cancer biology — Posted on 2024-02-29
125 Caspase-resistant ROCK1 expression prolongs survival of E-mu-Myc B cell lymphoma mice.
Mardilovich, K.; Naylor, G.; Julian, L.; Phinichkusolchit, N.; Keeshan, K.; Blyth, K.; Olson, M. F.
10.1101/2024.02.26.582074 — cancer biology — Posted on 2024-02-29
129 On Monitoring Brain Health from the Depths of Sleep: Feature Engineering and Machine Learning Insights for Digital Biomarker Development
McConnell, B. V.; Liu, Y.; Biswas, A. K.; Bettcher, B. M.; Medenblik, L. M.; Broussard, J. L.; Lucey, B. P.; Ramos, A. R.; Kheyfets, V. O.
10.1101/2024.02.27.581950 — neuroscience — Posted on 2024-02-29
130 A mediating framework in resting-state connectivity between the medial prefrontal cortex and anterior cingulate in mild cognitive impairment
Huang, Y. T.; Yan, S.-H.; Chuang, Y.-F.; Shih, Y.-C.; Huang, Y.-S.; Liu, Y.-C.; Kao, S. S.-C.; Chiu, Y.-L.; Fan, Y.-T.
10.1101/2024.02.27.582424 — neuroscience — Posted on 2024-02-29
132 Distinctive retinal peri-arteriolar versus peri-venular amyloid plaque distribution correlates with the cognitive performance
Dumitrascu, O. M.; Doustar, J.; Fuchs, D.-T.; Koronyo, Y.; Sherman, D. S.; Miller, M. S.; Johnson, K. O.; Carare, R. O.; Verdooner, S. R.; Lyden, P. D.; Schneider, J. A.; Black, K. L.; Koronyo-Hamaoui, M.
10.1101/2024.02.27.580733 — pathology — Posted on 2024-02-29
133 mRNA-delivered consensus allergens induce a neutralizing IgG response against food and pollen allergens
Moiniche, M.; Johansen, K. H.; Parron-Ballesteros, J.; Corneliussen, J. K.; Eriksen, H. H.; Kringelum, J. V.; Hadrup, S. R.; Luengo, O.; Cardona, V.; Bartra, J.; Pascal, M.; Turnay, J.; Villalba, M.; Munter, R.; Jenkins, T. P.; Laustsen, A. H.; Rivera-de-Torre, E.
10.1101/2024.02.26.582073 — bioengineering — Posted on 2024-02-29
136 ADAMTS7 Promotes Smooth Muscle Cell Foam Cell Expansion in Atherosclerosis
Chung, A.; Chang, H. K.; Pan, H.; Bashore, A. C.; Shuck, K.; Matias, C. V.; Gomez, J.; Yan, H.; Li, M.; Bauer, R. C.
10.1101/2024.02.26.582156 — pathology — Posted on 2024-02-29
137 Discovery of the First-in-class G9a/GLP PROTAC Degrader
Velez, J.; Han, Y.; Yim, H.; Yang, P.; Deng, Z.; Park, K.; Kabir, M.; Kaniskan, H.; Xiong, Y.; Jin, J.
10.1101/2024.02.26.582210 — biochemistry — Posted on 2024-02-29
138 Identification of robust cellular programs using reproducible LDA that impact sex-specific disease progression in different genotypes of a mouse model of AD
Rezaie, N.; Rebboah, E.; Williams, B. A.; Liang, H. Y.; Reese, F.; Balderrama-Gutierrez, G.; Dionne, L.; Reinholdt, L. G.; Trout, D.; Wold, B.; Mortazavi, A.
10.1101/2024.02.26.582178 — genomics — Posted on 2024-02-29
142 Genome concentration limits cell growth and modulates proteome composition in Escherichia coli
Makela, J.; Papagiannakis, A.; Lin, W.-H.; Lanz, M. C.; Glenn, S.; Swaffer, M.; Marinov, G. K.; Skotheim, J. M.; Jacobs-Wagner, C.
10.1101/2024.02.26.582181 — cell biology — Posted on 2024-02-29
147 Whole blood transcriptional profiles and the pathogenesis of tuberculous meningitis
Hai, H. T.; Nhat, L. T. H.; Tram, T. T. B.; Vinh, D. D.; Nath, A. P.; Donovan, J.; Thu, N. T. A.; Thanh, D. V.; Bang, N. D.; Ha, D. T. M.; Phu, N. H.; Nghia, H. D. T.; Van, L. H.; Inouye, M.; Thwaites, G. E.; Thuong, N. T. T.
10.1101/2023.10.06.561265 — molecular biology — Posted on 2024-02-29
149 Psilocybin prevents activity-based anorexia in female rats by enhancing cognitive flexibility: contributions from 5-HT1A and 5-HT2A receptor mechanisms.
Conn, K.; Milton, L. K.; Huang, K.; Munguba, H.; Ruuska, J.; Lemus, M. B.; Greaves, E.; Homman-Ludiye, J.; Oldfield, B. J.; Foldi, C. J.
10.1101/2023.12.12.571374 — neuroscience — Posted on 2024-02-29
151 Using a Förster-resonance energy transfer (FRET)-based detection system (FedEcs) to monitor nanoparticle cargo delivery to the brain
Khalin, I.; Adarsh, N.; Schifferer, M.; Wehn, A.; Boide-Trujillo, V. J.; Mamrak, U.; Shrouder, J. J.; Misgeld, T. J.; Filser, S.; Klymchenko, A. S.; Plesnila, N.
10.1101/2024.02.28.582471 — neuroscience — Posted on 2024-02-29
153 Rapid in situ mutation detection in extracellular vesicle-DNA
Rahman, M. M.; Wang, L.; Rahman, M. M.; Chen, Y.; Zhang, W.; Wang, J.; Lee, L.; Wan, Y.
10.1101/2024.02.26.582068 — bioengineering — Posted on 2024-02-29
157 Phylogenetic signal in primate tooth enamel proteins and its relevance for paleoproteomics
Krueger, J.; Fong Zazueta, R.; Alba, D. M.; Aymerich, X.; Beck, R. M. D.; Cappellini, E.; Carrillo Martin, G.; Cirilli, O.; Clark, N.; Cornejo, O. E.; Farh, K.; Ferrandez-Peral, L.; Juan, D.; Kelley, J. L.; Kuderna, L. F. K.; Little, J.; Orkin, J. D.; Paterson, R. S.; Pawar, H.; Marques-Bonet, T.; Lizano, E.
10.1101/2024.02.28.580462 — evolutionary biology — Posted on 2024-02-29
158 Cephalopod Sex Determination and its Ancient Evolutionary Origin Revealed by Chromosome-level Assembly of the California two-spot Octopus
Coffing, G. C.; Tittes, S.; Small, S. T.; Songco-Casey, J. O.; Piscopo, D. M.; Pungor, J. R.; Miller, A. C.; Niell, C.; Kern, A. D.
10.1101/2024.02.21.581452 — evolutionary biology — Posted on 2024-02-29
162 Coordination between cytoskeletal organization, cell contraction and extracellular matrix development, is depended on LOX for aneurysm prevention
Aviram, R.; Zaffryar-Eilot, S.; Kaganovsky, A.; Odeh, A.; Melamed, S.; Militsin, R.; Pinnock, C. B.; Shemesh, A.; Palty, R.; Ganesh, S. K.; Hasson, P.
10.1101/2024.02.23.581837 — cell biology — Posted on 2024-02-29
163 CEP44 is required for maintaining centriole duplication and spindle integrity
Zhang, D.; Wei, W.; Zou, X.; Meng, H.; Li, F.; Yao, M.; Teng, J.; Huang, N.; Chen, J.
10.1101/2023.11.20.567852 — cell biology — Posted on 2024-02-29
164 Proteomic and lipidomic alterations of high-density lipoprotein: Perimenopause is characterized by small triacylglycerols-enriched particles.
Lehti, S.; Korhonen, T.-M.; Soliymani, R.; Ruhanen, H.; Lahteenmaki, E.; Palviainen, M.; Siljander, P.; Lalowski, M.; Kakela, R.; Lehti, M.; Laakkonen, E. K.
10.1101/2024.01.10.574516 — molecular biology — Posted on 2024-02-29
166 A growth chart of brain function from infancy to adolescence based on electroencephalography
Iyer, K. K.; Roberts, J. A.; Waak, M.; Vogrin, S. J.; Kevat, A.; Chawla, J.; Haataja, L. M.; Lauronen, L.; Vanhatalo, S.; Stevenson, N. J.
10.1101/2023.07.07.548062 — neuroscience — Posted on 2024-02-29
167 High quality genome assembly of the brown hare (Lepus europaeus) with chromosome-level scaffolding
Michell, C.; Collins, J.; Laine, P. K.; Fekete, Z.; Tapanainen, R.; Wood, J. M. D.; Goffart, S.; Pohjoismaki, J. L. O.
10.1101/2023.08.29.555262 — genomics — Posted on 2024-02-28
168 The genome of Przewalski's horse (Equus ferus przewalskii)
Flack, N.; Hughes, L.; Cassens, J.; Enriquez, M.; Gebeyehu, S.; Alshagawi, M.; Hatfield, J.; Kauffman, A.; Brown, B.; Klaeui, C.; Malbrouk, I. F.; Walls, C.; Yeater, T.; Rivas, A.; Faulk, C.
10.1101/2024.02.20.581252 — genomics — Posted on 2024-02-28
169 Near telomere-to-telomere genome assemblies of two Chlorella species unveil the composition and evolution of centromeres in green algae
Wang, B.; Jia, Y.; Dang, N.; Yu, J.; Bush, S. J.; Gao, S.; He, W.; Wang, S.; Guo, H.; Yang, X.; Ma, W.; Ye, K.
10.1101/2024.02.27.582245 — genomics — Posted on 2024-02-29
171 The binding of Mint/X11 PDZ domains to CaV2 calcium channels predates bilaterian animals
Harracksingh, A. N.; Singh, A.; Mayorova, T.; Bejoy, B.; Hornbeck, J.; Elkhatib, W.; McEdwards, G.; Gauberg, J.; Taha, A. R. W.; Islam, I. M.; Erclik, T.; Currie, M. A.; Noyes, M.; Senatore, A.
10.1101/2024.02.26.582151 — evolutionary biology — Posted on 2024-02-29
172 One Hundred Years of Influenza A Evolution
Nielsen, B. F.; Berrig, C.; Grenfell, B. T.; Andreasen, V.
10.1101/2024.02.27.582392 — evolutionary biology — Posted on 2024-02-29
177 Multimodal brain age prediction using machine learning: combining structural MRI and 5-HT2AR PET derived features
Dörfel, R. P.; Arenas-Gomez, J. M.; Svarer, C.; Ganz, M.; Knudsen, G. M.; Svensson, J.; Plaven-Sigray, P.
10.1101/2024.02.05.578968 — neuroscience — Posted on 2024-02-28
182 Unsupervised segmentation of 3D microvascular photoacoustic images using deep generative learning
Sweeney, P. W.; Hacker, L.; Lefebvre, T. L.; Brown, E. L.; Gröhl, J.; Bohndiek, S. E.
10.1101/2023.04.30.538453 — biophysics — Posted on 2024-02-28
185 MAPLE: A Hybrid Framework for Multi-Sample Spatial Transcriptomics Data
Jeon, H.; Allen, C.; Ovando-Ricardez, J. A.; Chang, Y.; Rosas, L.; Vanegas, N.-D. P.; Cheng, H.; Xie, J.; Wang, C.; Mora, A. L.; Rojas, M.; Ma, Q.; Chung, D.
10.1101/2022.02.28.482296 — bioinformatics — Posted on 2024-02-28
186 Exploring the conformational ensembles of protein-protein complex with transformer-based generative model
Wang, J.; Wang, X.; Chu, Y.; Li, C.; Li, X.; Meng, X.; Fang, Y.; No, K. T.; Mao, J.; Zeng, X.
10.1101/2024.02.24.581708 — bioinformatics — Posted on 2024-02-28
187 Prominin 1 and Tweety Homology 1 both induce extracellular vesicle formation
Bell, T. A.; Luce, B. E.; Hakim, P.; Ananda, V. Y.; Dardari, H.; Nguyen, T. H.; Monshizadeh, A.; Chao, L. H.
10.1101/2023.11.08.566258 — biochemistry — Posted on 2024-02-28
189 Spatial Multiomics Reveal the Role of Wnt Modulator, Dkk2, in Palatogenesis
Oliver Pina, J.; Raju, R.; Roth, D. M.; Winchester, E. W.; Padilla, C.; Iben, J.; Faucz, F. R.; Cotney, J. L.; D'Souza, R. N.
10.1101/2023.05.16.541037 — developmental biology — Posted on 2024-02-28
190 Characterization of Pro-Fibrotic Signaling Pathways using Human Hepatic Organoids
Guan, Y.; Fang, Z.; Hu, A.; Roberts, S.; Wang, M.; Ren, W.; Johansson, P. K.; Heilshorn, S. C.; Enejder, A.; Peltz, G.
10.1101/2023.04.25.538102 — cell biology — Posted on 2024-02-28
191 Pathway-enhanced Transformer-based model for robust enumeration of cell types from the cell-free transcriptome
Yan, S.; Tian, X.; Qin, Y.; Li, J.; Yang, T.; Yu, D.; Liu, W.; Sun, J.; Hu, C.; Zhou, Q.; Liu, Z.; Wang, W.-J.
10.1101/2024.02.28.582494 — bioinformatics — Posted on 2024-02-28
195 A Massively Parallel CRISPR-Based Screening Platform for Modifiers of Neuronal Activity
Boggess, S. C.; Gandhi, V.; Tsai, M.-C.; Chou, J. Y.-Y.; Hu, X.; Yadanar, L.; Teyssier, N.; Eidenschenk, C.; Hanson, J. E.; Tian, R.; Kampmann, M.
10.1101/2024.02.28.582546 — neuroscience — Posted on 2024-02-28
198 Virological traits of the SARS-CoV-2 BA.2.87.1 lineage
Zhang, L.; Dopfer-Jablonka, A.; Nehlmeier, I.; Kempf, A.; Graichen, L.; Calderon Hampel, N.; Cossmann, A.; Stankov, M. V.; Morillas Ramos, G.; Schulz, S. R.; Jaeck, H.-M.; Behrens, G. M. N.; Poehlmann, S.; Hoffmann, M.
10.1101/2024.02.27.582254 — molecular biology — Posted on 2024-02-28
202 Novel misos shape distinct microbial ecologies: opportunities for flavourful sustainable food innovation
Kothe, C. I.; Caroe, C.; Mazel, F.; Zilber, D.; Cruz-Morales, P.; Mohellibi, N.; Evans, J.
10.1101/2024.02.28.582453 — microbiology — Posted on 2024-02-28
207 Liquid phase electron microscopy of bacterial ultrastructure.
Caffrey, B. J.; Pedrazo-Tardajos, A.; Liberti, E.; Gaunt, B.; Kim, J. S.; Kirkland, A. I.
10.1101/2024.02.27.580996 — microbiology — Posted on 2024-02-28
209 Transient inhibition of cell division in competent pneumococcal cells results from deceleration of the septal peptidoglycan complex
Juillot, D.; Billaudeau, C.; Barbotin, A.; Lablaine, A.; Mortier-Barriere, I.; Polard, P.; Campo, N.; LOPEZ, R. C.
10.1101/2024.02.28.582556 — microbiology — Posted on 2024-02-28
210 The S2 subunit of spike encodes diverse targets for functional antibody responses to SARS-CoV-2
Guenthoer, J.; Garrett, M. E.; Lilly, M.; Depierreux, D. M.; Ruiz, F.; Chi, M.; Stoddard, C. I.; Chohan, V.; Sung, K.; Ralph, D.; Chu, H. Y.; Matsen, F. A.; Overbaugh, J.
10.1101/2024.02.26.582219 — immunology — Posted on 2024-02-28
211 A nonlinear code for event probability in the human brain
Foucault, C.; Bounmy, T.; Demortain, S.; Thirion, B.; Eger, E.; MEYNIEL, F.
10.1101/2024.02.28.582455 — neuroscience — Posted on 2024-02-28
212 Reconstructing Voice Identity from Noninvasive Auditory Cortex Recordings
Lamothe, C.; Thoret, E.; Trapeau, R.; Giordano, B. L.; Sein, J.; Takerkart, S.; Ayache, S.; Artieres, T.; Belin, P.
10.1101/2024.02.27.582302 — neuroscience — Posted on 2024-02-28
213 The Douglas Bell Canada Brain Bank Post-mortem Brain Imaging Protocol
Dadar, M.; Sanches, L.; Fouquet, J.; Moqadam, R.; Alasmar, Z.; Mirault, D.; Maranzano, J.; Mechawar, N.; Chakravarty, M.; Zeighami, Y.
10.1101/2024.02.27.582303 — neuroscience — Posted on 2024-02-28
218 Interneuron loss and microglia activation by transcriptome analyses in the basal ganglia of Tourette syndrome
Wang, Y.; Fasching, L.; Wu, F.; Huttner, A.; Berretta, S.; Roberts, R.; Leckman, J. F.; Abyzov, A.; Vaccarino, F. M.
10.1101/2024.02.28.582504 — neuroscience — Posted on 2024-02-28
228 The effect of molnupiravir and nirmatrelvir on SARS-CoV-2 genome diversity in infected and immune suppressed mice
Penrice-Randal, R.; Bentley, E. G.; Sharma, P.; Kirby, A.; Donovan-Banfield, I.; Kipar, A.; Mega, D. F.; Bramwell, C.; Sharp, J.; Owen, A.; Hiscox, J. A.; Stewart, J. P.
10.1101/2024.02.27.582110 — pharmacology and toxicology — Posted on 2024-02-28
229 Carboxylated graphene: A novel approach for enhanced IgA-SARS-CoV-2 electrochemical biosensing
Freire, L. d. S.; Ruzo, C. M.; Salgado, B. B.; Gandarilla, A.; Barcelay, Y. R.; Tavares, A. P. M.; Nobre, F. X.; Lalwani, P.; Astofi-Filho, S.; Brito, W.
10.1101/2024.02.27.582131 — bioengineering — Posted on 2024-02-28
231 Inhibition of SARS-CoV-2 infection by Porphyromonas gingivalis and the oral microbiome
Bontempo, A.; Chirino, A.; Heidari, A.; Lugo, A.; Shindo, S.; Pastore, M. R.; Antonson, S.; Godoy, C.; Nichols, F.; Potempa, J.; Davey, M.; Kawai, T.; Cayabyab, M.
10.1101/2024.02.27.582258 — microbiology — Posted on 2024-02-28
233 Tissue-specific and endogenous protein labeling with split fluorescent proteins
Ligunas, G. D.; Paniagua, G.; LaBelle, J.; Ramos-Martinez, A.; Shen, K.; Gerlt, E. H.; Aguilar, K.; Nguyen, A.; Materna, S. C.; Woo, S.
10.1101/2024.02.28.581822 — developmental biology — Posted on 2024-02-28
236 Pre-challenge gut microbial signature predicts RhCMV/SIV vaccine efficacy in rhesus macaques
Brochu, H. N.; Smith, E.; Jeong, S.; Carlson, M.; Hansen, S. G.; Tisoncik-Go, J.; Law, L.; Picker, L. J.; Gale, M.; Peng, X.
10.1101/2024.02.27.582186 — microbiology — Posted on 2024-02-28
237 Designed mosaic nanoparticles enhance cross-reactive immune responses in mice
Wang, E.; Cohen, A. A.; Caldera, L. F.; Keeffe, J. R.; Rorick, A. V.; Aida, Y. M.; Gnanapragasam, P. N. P.; Bjorkman, P. J.; Chakraborty, A. K.
10.1101/2024.02.28.582544 — immunology — Posted on 2024-02-28
241 Neural pathways and computations that achieve stable contrast processing tuned to natural scenes
Gür, B.; Ramirez, L.; Cornean, J.; Thurn, F.; Molina-Obando, S.; Ramos-Traslosheros, G.; Silies, M.
10.1101/2024.02.27.582271 — neuroscience — Posted on 2024-02-28
242 Linewidth-related bias in modelled concentration estimates from GABA-edited 1H-MRS
Craven, A. R.; Bell, T. K.; Ersland, L.; Harris, A. D.; Hugdahl, K.; Oeltzschner, G.
10.1101/2024.02.27.582249 — neuroscience — Posted on 2024-02-28
244 MVComp toolbox: MultiVariate Comparisons of brain MRI features accounting for common information across metrics
Tremblay, S. A.; Alasmar, Z.; Pirhadi, A.; Carbonell, F.; Iturria-Medina, Y.; Gauthier, C. J.; Steele, C. J.
10.1101/2024.02.27.582381 — neuroscience — Posted on 2024-02-28
245 Absence seizures and sleep abnormalities in a rat model of GRIN2B neurodevelopmental disorder
Hristova, K.; Fasol, M. C.; McLaughlin, N.; Nawaz, S.; Taskiran, M.; Buller-Peralta, I.; Bassi, A.; Ocampo-Garces, A.; Escudero, J.; Kind, P. C.; Gonzalez-Sulser, A.
10.1101/2024.02.27.582289 — neuroscience — Posted on 2024-02-28
249 Agency accounts for the effect of FB transparency onmotor imagery neurofeedback performance
Dussard, C.; Pillette, L.; Dumas, C.; Pierrieau, E.; Hugueville, L.; Lau, B.; Jeunet, C.; George, N.
10.1101/2024.02.27.582270 — neuroscience — Posted on 2024-02-28
250 Decoding Music-Evoked Valence and Arousal: Unraveling the Neural Correlates of Naturalistic Music Characteristics through fMRI
Sayal, A.; Guedes, A. G.; Almeida, I.; Pereira, D. J.; Lima, C.; Panda, R.; Paiva, R. P.; Sousa, T.; Castelo-Branco, M.; Bernardino, I.; Direito, B.
10.1101/2024.02.27.582309 — neuroscience — Posted on 2024-02-28
253 GLP-1 receptor agonism ameliorates Parkinsons disease through modulation of neuronal insulin signalling and glial suppression
Athauda, D.; Evans, J. R.; Sanchez, L.; Virdi, G.; Lopez Garcia, P.; Wernick, A.; Wagen, A.; D'Sa, K.; Lachica, J.; Strohbuecker, S.; Vecchi, G.; Leighton, C.; Saleeb, R. S.; OShaughnessy, J.; Toomey, C.; Vijiaratnam, N.; Girges, C.; Li, Y.; Mustapic, M.; Ismail, K.; Davies, M.; Kapogiannis, D.; Choi, M. L.; Ryten, M.; Horrocks, M. H.; Greig, N. H.; Foltynie, T.; Gandhi, S.
10.1101/2024.02.28.582460 — neuroscience — Posted on 2024-02-28
255 Using a Foerster-resonance energy transfer (FRET)-based detection system (FedEcs) to monitor nanoparticle cargo delivery to the brain
Khalin, I.; Adarsh, N.; Schifferer, M.; Wehn, A.; Boide-Trujillo, V. J.; Mamrak, U.; Shrouder, J. J.; Misgeld, T. J.; Filser, S.; Klymchenko, A. S.; Plesnila, N.
10.1101/2024.02.28.582471 — neuroscience — Posted on 2024-02-28
256 Hippocampal purinergic P2X7 receptor level is increased in Alzheimer's disease patients, and associated with amyloid and tau pathologies
Maschio, C.; Wang, J.; Maheshwari, U.; Keller, A.; Rominger, A.; Konietzko, U.; Hock, C.; Nitsch, R. M.; Nordberg, A.; Ni, R.
10.1101/2024.02.28.582443 — neuroscience — Posted on 2024-02-28
258 L-Type calcium channels and TRPC3 channels shape brain pericyte calcium signaling and hemodynamics throughout the arteriole to capillary network in vivo
Meza-Resillas, J.; O'Hara, F.; Kaushik, S.; Stobart, M. J.; Ahmadpour, N.; Kantroo, M.; Shabanipour, S.; Del Rosario, J.; Rodriguez, M. C.; Koval, D.; Glueck, C.; Weber, B.; Stobart, J. L.
10.1101/2024.02.27.582351 — neuroscience — Posted on 2024-02-28
262 MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer
Klingbeil, O.; Skopelitis, D.; Tonelli, C.; Alpsoy, A.; Minicozzi, F.; Aggarwal, D.; Russo, S.; Ha, T.; Demerdash, O. E.; Spector, D. L.; Tuveson, D. A.; Cifani, P.; Vakoc, C. R.
10.1101/2024.02.26.582171 — cancer biology — Posted on 2024-02-28
263 Heterogeneity and evolution of DNA mutation rates in microsatellite stable colorectal cancer
Grassi, E.; Vurchio, V.; Cresswell, G. D.; Catalano, I.; Lupo, B.; Sassi, F.; Galimi, F.; Borgato, S.; Ferri, M.; Viviani, M.; Pompei, S.; Urgese, G.; Chen, B.; Zanella, E. R.; Cottino, F.; Bardelli, A.; Cosentino Lagormarsino, M.; Sottoriva, A.; Trusolino, L.; Bertotti, A.
10.1101/2024.02.26.582054 — cancer biology — Posted on 2024-02-28
264 Deciphering rapid cell signaling and control of cell motility by reverse opto-chemical engineering
Hamzeh, H.; Gong, A.; Balbach, M.; Fridman, D.; Koerschen, H. G.; Pascal, R.; Lavryk, F.; Rennhack, A.; Seifert, R.; Hernandez-Clavijo, A.; Pifferi, S.; Dusend, V.; Fleischmann, B.; Sasse, P.; Menini, A.; Friedrich, B. M.; Alvarez, L.; Kaupp, U. B.
10.1101/2024.02.26.582067 — biophysics — Posted on 2024-02-28
271 CD34-positive monocytes are highly susceptible to HIV-1
Takahashi, N.; Noyori, O.; Komohara, Y.; Eltalkhawy, Y. M.; Hirayama, M.; Yoshida, R.; Nakayama, H.; Kuroda, M. J.; Nomura, T.; Ishii, H.; Matano, T.; Gatanaga, H.; Oka, S.; Takiguchi, M.; Suzu, S.
10.1101/2024.02.26.582226 — immunology — Posted on 2024-02-28
272 Perinatal Brain Injury Triggers Niche-Specific Changes to Cellular Biogeography
Tahmasian, N.; Feng, M. Y.; Arbabi, K.; Rusu, B.; Cao, W.; Kukreja, B.; Lubotzky, A.; Wainberg, M.; Tripathy, S.; Kalish, B. T.
10.1101/2024.02.25.581974 — neuroscience — Posted on 2024-02-28
276 CRE mice exhibit hyperactive and impulsive behavior affecting their learning and retention performances
Desor, F.; El Hajj, A.; Herzine, A.; Djelti, F.; Bombail, V.; Denis, I.; Oster, T.; Lanhers, M.-C.; Malaplate, C.; Yen, F. T.; Claudepierre, T.
10.1101/2024.02.27.582228 — animal behavior and cognition — Posted on 2024-02-28
279 Supplementary motor area disinhibition during motor sequence learning: A TMS-EEG study
Thong, S.; Doery, E.; Biabani, M.; Rogasch, N. C.; Chong, T. T.- J.; Hendrikse, J.; Coxon, J. P.
10.1101/2024.02.26.581077 — neuroscience — Posted on 2024-02-28
281 in silico transcriptome dissection of neocortical excitatory neurogenesis via joint matrix decomposition and transfer learning
Sonthalia, S.; Li, G.; Blanco, X. M.; Casella, A.; Liu, J.; Stein-O'Brien, G.; Caffo, B.; Adkins, S.; Orvis, J.; Hertzano, R.; Mahurkar, A.; Gillis, J. A.; Werner, J.; Ma, S.; Micali, N.; Sestan, N.; Rakic, P.; Baro, G. S.; Ament, S. A.; Colantuoni, C.
10.1101/2024.02.26.581612 — neuroscience — Posted on 2024-02-28
282 A model for cortical activity sequences
Lehr, A. B.; Erzmann, F.; Michaelis, C.; Nowak, J.; Gail, A.; Kumar, A.; Tetzlaff, C.
10.1101/2024.02.25.581959 — neuroscience — Posted on 2024-02-28
283 The DREAM implant: A Lightweight, Modular and Cost-Effective Implant System for Chronic Electrophysiology in Head-fixed and Freely Behaving Mice
Schroeder, T.; Taylor, R.; Abd El Hay, M.; Nemri, A.; Franca, A.; Battaglia, F.; Tiesinga, P.; Schoelvinck, M. L.; Havenith, M. N.
10.1101/2024.02.26.582029 — neuroscience — Posted on 2024-02-28
284 A parabrachial hub for the prioritization of survival behavior
Goldstein, N.; Maes, A.; Allen, H. N.; Nelson, T. S.; Kruger, K. A.; Kindel, M.; Smith, N. K.; Carty, J. R.; Villari, R. E.; Cho, E.; Marble, E. L.; Khanna, R.; Taylor, B. K.; Kennedy, A.; Betley, J. N.
10.1101/2024.02.26.582069 — neuroscience — Posted on 2024-02-28
285 Evidence for shallow cognitive maps in schizophrenia
Karagoz, A. B.; Moran, E. K.; Barch, D.; Kool, W.; Reagh, Z. M.
10.1101/2024.02.26.582214 — neuroscience — Posted on 2024-02-28
286 Disentangling Mnemonic Metacognition from Confidence by Communication between the Precuneus and Hippocampus
Pan, K.; Guo, X.; Zheng, Z.; Zhu, Z.; Wu, H.; Zhu, J.; Santos-Pata, D.; Zhang, J.; Kwok, S. C.; Jiang, H.
10.1101/2024.02.26.581526 — neuroscience — Posted on 2024-02-28
290 The lipidome of posttraumatic stress disorder
Bhargava, A.; Knapp, J. D.; Fiehn, O.; Neylan, T. C.; Inslicht, S. S.
10.1101/2024.02.23.581833 — systems biology — Posted on 2024-02-28
293 A targetable PREX2/RAC1/PI3Kβ signalling axis confers resistance to clinically relevant therapeutic approaches in melanoma
Ford, C. A.; Koludrovic, D.; Centeno, P. P.; Foth, M.; Tsonou, E.; Vlahov, N.; Sphyris, N.; Gilroy, K.; Bull, C.; Nixon, C.; Serrels, B.; Munro, A. F.; Dawson, J. C.; Carragher, N. O.; Pavet, V.; Hornigold, D. C.; Dunne, P. D.; Downward, J.; Welch, H. C. E.; Barry, S. T.; Sansom, O. J.; Campbell, A. D.
10.1101/2024.02.26.580534 — cancer biology — Posted on 2024-02-28
294 Data-driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes
Nourbakhsh, M.; Tom, N.; Schroeder Lassen, A.; Brasch Lind Petersen, H.; Kristoffer Stoltze, U.; Wadt, K.; Schmiegelow, K.; Tiberti, M.; Papaleo, E.
10.1101/2024.02.26.582026 — cancer biology — Posted on 2024-02-28
298 Cell morphogenesis via shape-guided self-propelled treadmilling actin waves
Yagami, K.; Baba, K.; Misu, S.; Katsuno-Kambe, H.; Minegishi, T.; Okano, K.; Sakumura, Y.; Hosokawa, Y.; Inagaki, N.
10.1101/2024.02.28.582450 — cell biology — Posted on 2024-02-28
299 Circulating plasma fibronectin affects normal adipose tissue insulin sensitivity and adipocyte differentiation
Kaartinen, M. T.; Mahmoodi, M.; Dahaghi, E. M.; Nabavi, M.-H.; Penalva, Y.; Gosaine, A.; Murshed, M.; Couldwell, S.; Munter, L.
10.1101/2024.02.28.582553 — cell biology — Posted on 2024-02-28
301 Alpha-synuclein aggregates trigger anti-viral immune pathways and RNA editing in human astrocytes
D'Sa, K.; Choi, M. L.; Wagen, A. Z.; Seto-Salvia, N.; Kopach, O.; Evans, J. R.; Rodrigues, M.; Lopez-Garcia, P.; Ghareeb, A.; Bayne, J.; Grant-Peters, M.; Garcia-Ruiz, S.; Chen, Z.; Rodriques, S.; Athauda, D.; Gustavsson, E.; Gagliano Taliun, S. A.; Reynolds, R. H.; Young, G.; Strohbuecker, S.; Warner, T.; Rusakov, D. A.; Patani, R.; Bryant, C.; Klenerman, D. A.; Gandhi, S.; Ryten, M.
10.1101/2024.02.26.582055 — neuroscience — Posted on 2024-02-28
304 Cyclase-associated protein 1 (CAP1) represses MRTF-SRF-dependent gene expression in the mouse cerebral cortex
Khudayberdiev, S.; Weiss, K.; Heinze, A.; Colombaretti, D.; Trausch, N.; Linne, U.; Rust, M. B.
10.1101/2024.02.26.582060 — neuroscience — Posted on 2024-02-28
305 Pre-existing visual responses in a projection-defined dopamine population explain individual learning trajectories
Pan Vazquez, A.; Sanchez Araujo, Y.; McMannon, B.; Louka, M.; Bandi, A.; Haetzel, L.; International Brain Laboratory, n.; Pillow, J. W.; Daw, N. D.; Witten, I.
10.1101/2024.02.26.582199 — neuroscience — Posted on 2024-02-28
307 Imaging brain vascular function in Cystic Fibrosis: an MRI study of cerebral blood flow and brain oxygenation
Chandler, H. L.; Germuska, M.; Lancaster, T. M.; Xanthe, C.; O'Leary, C.; Stirk, S.; Murphy, K.; Metzler-baddeley, C.; Wise, R. G.; Duckers, J.
10.1101/2024.02.25.581905 — neuroscience — Posted on 2024-02-28
308 Chemically induced senescence prompts functional changes in human microglia-like cells
Armanville, S.; Tocco, C.; Haj Mohamad, Z.; Clarke, D.; Robitaille, R.; Drouin-Ouellet, J.
10.1101/2024.02.27.582168 — neuroscience — Posted on 2024-02-28
312 Opposing Motor Memories in the Direct and Indirect Pathways of the Basal Ganglia
Wen, K.; Shi, Z.; Yu, P.; Mo, L.; Sullere, S.; Yang, V.; Westneat, N.; Beeler, J. A.; McGehee, D. S.; Doiron, B.; Zhuang, X.
10.1101/2024.02.26.582159 — neuroscience — Posted on 2024-02-28
313 NF-kB/NLRP3 Translational Inhibition by Nanoligomer Therapy Mitigates Ethanol and Advanced Age-Related Neuroinflammation
Anton, P. E.; Nagpal, P.; Moreno, J.; Busquet, N.; Burchill, M. A.; Chatterjee, A.; Mesches, M.; Kovacs, E. J.; McCullough, R. L.
10.1101/2024.02.26.582114 — neuroscience — Posted on 2024-02-28
316 Distal tuft dendrites shape and maintain new place fields
O'Hare, J. K.; Wang, J.; Shala, M. D.; Polleux, F.; Losonczy, A.
10.1101/2024.02.26.582144 — neuroscience — Posted on 2024-02-28
317 Long-access heroin self-administration induces region specific reduction of grey matter volume and microglia reactivity in the rat.
Cannella, N.; Tambalo, S.; Lunerti, V.; Scuppa, G.; de Vivo, L.; Abdulmalek, S.; Kinen, A.; Mackle, J.; Kuhn, B.; Solberg-Woods, L. N.; Chung, D.; Kalivas, P.; Soverchia, L.; Ubaldi, M.; Hardiman, G.; Bifone, A.; Ciccocioppo, R.
10.1101/2024.02.26.582024 — neuroscience — Posted on 2024-02-28
320 Expanding the BonnMu sequence-indexed repository of transposon induced maize (Zea mays L.) mutations in dent and flint germplasm
Win, Y. N.; Stöcker, T.; Du, X.; Brox, A.; Pitz, M.; Klaus, A.; Schoof, H.; Hochholdinger, F.; Marcon, C.
10.1101/2024.02.24.581857 — genomics — Posted on 2024-02-28
322 ScISOr-ATAC reveals convergent and divergent splicing and chromatin specificities between matched cell types across cortical regions, evolution, and in Alzheimer's disease.
Hu, W.; Foord, C.; Hsu, J.; Fan, L.; Corley, M. J.; Bhatia, T. N.; Xu, S.; Belchikov, N.; He, Y.; Pang, A. P.; Lanjewar, S. N.; Jarroux, J.; Joglekar, A.; Milner, T. A.; Ndhlovu, L.; Zhang, J.; Butelman, E.; Sloan, S. A.; Lee, V. M.; Gan, L.; Tilgner, H. U.
10.1101/2024.02.24.581897 — genomics — Posted on 2024-02-28
323 Altruistic disease signalling in ant colonies
Dawson, E. H.; Kampleitner, N.; Robb, J.; Strahodinsky, F.; Grasse, A. V.; Cremer, S.
10.1101/2024.02.27.582277 — animal behavior and cognition — Posted on 2024-02-28
325 Multi-ancestry tandem repeat association study of hair color using exome-wide sequencing
Fazzari, V.; Moo-Choy, A.; Panoyan, M. A.; Abbatangelo, C. L.; Polimanti, R.; Novroski, N. M.; Wendt, F. R.
10.1101/2024.02.24.581865 — genomics — Posted on 2024-02-28
326 ILLUSORY LIGHT DRIVES PUPIL RESPONSES IN PRIMATES
Durand, J.-B.; Marchand, S.; Nasres, I.; Laeng, B.; De Castro, V.
10.1101/2024.02.27.582033 — animal behavior and cognition — Posted on 2024-02-28
328 Whole genome assembly of the Little Millet (Panicum sumatrense) genome: A climate resilient crop species
Das, R. R.; Kumar, A.; Baghel, D. S.; Mahato, A. K.; Dey, N.; Mukherjee, P. K.; Pradhan, S.
10.1101/2024.02.26.582036 — genomics — Posted on 2024-02-28
329 Traits related to pollination and mating result in diverse reproductive strategies in angiosperms
Helmstetter, A. J.; Mendez, M.; Schonenberger, J.; Burgarella, C.; Anderson, B.; Balthazar, M. v.; Billiard, S.; Boer, H. d.; Cros, J.; Delecroix, P.-A.; Dufay, M.; Pannell, J.; Savova Bianchi, D.; Schoen, D.; Vallejo-Marin, M.; Zenil-Ferguson, R.; Sauquet, H.; Glemin, S.; Kafer, J.
10.1101/2024.02.26.582019 — evolutionary biology — Posted on 2024-02-28
333 STRESS GRANULE-RELATED GENES DURING EMBRYOGENESIS OF AN INVERTEBRATE CHORDATE
Drago, L.; Pennati, A.; Rothbaecher, U.; Ashita, R.; Hashimoto, S.; Saito, R.; Fujiwara, S.; Ballarin, L.
10.1101/2024.02.26.582042 — developmental biology — Posted on 2024-02-28
338 SUMO-mediated regulation of a H3K4me3 reader controls germline development in C. elegans
Carvalho, C. A.; Bening Abu-Shach, U.; Raju, A.; Vershinin, Z.; Levy, D.; Boxem, M.; Broday, L.
10.1101/2024.02.27.582283 — cell biology — Posted on 2024-02-28
339 Nir1-LNS2 is a novel phosphatidic acid biosensor that reveals mechanisms of lipid production
Weckerly, C. C.; Rahn, T. A.; Ehrlich, M.; Wills, R. C.; Pemberton, J. G.; Airola, M. V.; Hammond, G. R.
10.1101/2024.02.28.582557 — cell biology — Posted on 2024-02-28
340 O-GlcNAcylation of the intellectual disability protein DDX3X exerts proteostatic cell cycle control
van Aalten, D. M. F.; Mitchell, C. W.; Yuan, H.; Authier, F.; Sonderstrup-Jensen, M.; Ferenbach, A. T.; d'Alessio, A. M.
10.1101/2024.02.28.582457 — cell biology — Posted on 2024-02-28
341 Nanoscale architecture and dynamics of CaV1.3 channel clusters in cardiac myocytes revealed by single channel nanoscopy
Schwenzer, N.; Tsukanov, R.; Kohl, T.; Basak, S.; Seibertz, F.; Voigt, N.; Enderlein, J.; Lehnart, S. E.
10.1101/2024.02.26.582084 — cell biology — Posted on 2024-02-28
347 The intracellular Ca2+ sensitivity of transmitter release from neocortical boutons
Bornschein, G.; Brachtendorf, S.; Eshra, A.; Kraft, R.; Eilers, J.; Hallermann, S.; Schmidt, H.
10.1101/2024.02.26.582057 — neuroscience — Posted on 2024-02-28
348 AI Derived Therapeutic Development for the Treatment of Opioid Use Disorder
Lallai, V.; Martin, A. C.; Fowler, J. P.; Bautista, M.; Mogul, A. S.; Cheepluesak, J. E.; Mirzaei, S.; Jenkins, I.; Lakey, J. R.; Tinder, R.; Fowler, C. D.
10.1101/2024.02.26.579391 — neuroscience — Posted on 2024-02-28
349 Controlling the human connectome with spatially diffuse input signals
Betzel, R. F.; Puxeddu, M. G.; Seguin, C.; Bazinet, V.; Luppi, A.; Podschun, A.; Singleton, S. P.; Faskowitz, J.; Parakkattu, V.; Misic, B.; Markett, S.; Kuceyeski, A.; Parkes, L.
10.1101/2024.02.27.581006 — neuroscience — Posted on 2024-02-28
350 Decoding the spatiotemporal dynamic neural representation of repetitive facial expression imitation
Liu, Q.; Zhou, X.; Zhu, S.; Liu, C.; Yang, Y.; Lan, C.; Song, X.; Becker, B.; Kendrick, K. M.; Zhao, W.
10.1101/2024.02.26.582020 — neuroscience — Posted on 2024-02-28
351 Adoptive transfer of mitochondrial antigen-specific CD8+ T-cells in mice causes parkinsonism and compromises the dopamine system
Elemeery, M. N.; Tchung, A.; Boulet, S.; Mukherjee, S.; Giguere, N.; Daudelin, J.-F.; Hetu-Arbour, R.; Matheoud, D.; STRATTON, J. A.; Labrecque, N.; Trudeau, L.-E.
10.1101/2024.02.26.582098 — neuroscience — Posted on 2024-02-28
352 Stimulation mapping and whole-brain modeling reveal gradients of excitability and recurrence in cortical networks
Momi, D.; Wang, Z.; Parmigiani, S.; Mikulan, E.; Bastiaens, S.; Oveisi, M.; Kadak, K.; Gaglioti, G.; Waters, A.; Hill, S.; Pigorini, A.; Keller, C.; Griffiths, J. D.
10.1101/2024.02.26.581277 — neuroscience — Posted on 2024-02-28
355 Emo-FilM: A multimodal dataset for affective neuroscience using naturalistic stimuli
Morgenroth, E.; Moia, S.; Vilaclara, L.; Fournier, R.; Muszynski, M.; Ploumitsakou, M.; Almato-Bellavista, M.; Vuilleumier, P.; Van de Ville, D.
10.1101/2024.02.26.582043 — neuroscience — Posted on 2024-02-28
357 Human stem cell derived neurons and astrocytes to detect auto-reactive IgG in neurological diseases
Mathias, A.; Perriot, S.; Jones, S.; Canales, M.; Bernard-Valnet, R.; Gimenez, M.; Torcida, N.; Oberholster, L.; Hottinger, A. F.; Zekeridou, A.; Theaudin, M.; Pot, C.; Du Pasquier, R.
10.1101/2024.02.26.582006 — neuroscience — Posted on 2024-02-28
358 Comparative study of enriched dopaminergic neurons from siblings with Gaucher disease discordant for parkinsonism
Hertz, E.; Perez, G.; Hao, Y.; Rytel, K.; Ma, C.; Kirby, M.; Anderson, S.; Wincovitch, S.; Andersh, K.; Ahfeldt, T.; Blanchard, J.; Qi, Y. A.; Lopez, G.; Tayebi, N.; Sidransky, E.; Chen, Y.
10.1101/2024.02.25.581985 — neuroscience — Posted on 2024-02-28
359 Steeper or Faster? Impacts of Similar-intensity Running Conditions on Heart Rate Variability
ElDash, V. M.; ElDash, I. M. C. A.; Marques, F. S.; Natali, J. E. S.; Chaui-Berlinck, J. G.
10.1101/2024.02.23.581819 — physiology — Posted on 2024-02-28
360 Short periods of decreased water flow may modulate long-term ocean acidification in reef-building corals
Martins, C. P. P.; Simancas-Giraldo, S. M.; Schubert, P.; Wall, M.; Wild, C.; Wilke, T.; Ziegler, M.
10.1101/2024.02.23.581783 — physiology — Posted on 2024-02-28
361 CTAT-LR-fusion: accurate fusion transcript identification from long and short read isoform sequencing at bulk or single cell resolution
Qin, Q.; Popic, V.; Yu, H.; White, E.; Khorgade, A.; Shin, A.; Wienand, K.; Dondi, A.; Beerenwinkel, N.; Vazquez, F.; AlKhafaji, A. M.; Haas, B. J.
10.1101/2024.02.24.581862 — cancer biology — Posted on 2024-02-28
362 Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR-T cells
Kasap, C.; Izgutdina, A.; Patino-Escobar, B.; Kang, A.; Chilakapati, N.; Akagi, N.; Johnson, H.; Rashid, T.; Werner, J.; Barpanda, A.; Geng, H.; Lin, Y.-H. T.; Rampersaud, S.; Gil-Alos, D.; Sobh, A.; Dupere-Richer, D.; Wicaksono, G.; Kelii, K. M. K.; Dalal, R.; Ramos, E.; Vijayanarayanan, A.; Salangsang, F.; Phojanakong, P.; Camara Serrano, J. A.; Zakraoui, O.; Tariq, I.; Steri, V.; Shanmugam, M.; Boise, L. H.; Kortemme, T.; Stieglitz, E.; Licht, J. D.; Karlon, W. J.; Barwick, B. G.; Wiita, A.
10.1101/2024.02.24.581875 — cancer biology — Posted on 2024-02-28
363 Oncogenic GNAS drives a gastric pylorus program in intraductal papillary mucinous neoplasms of the pancreas
Trinh, V. Q.-H.; Ankenbauer, K. E.; Liu, J.; Batardiere, M.; Maurer, H. C.; Copeland, C.; Wong, J.; Ben-Levy, O.; Torbit, S. M.; Jarvis, B.; Revetta, F.; Ivanov, S.; Jyotsana, N.; Makino, Y.; Ruelas, A. M.; Means, A. L.; Maitra, A.; Tan, M. C. B.; DelGiorno, K. E.
10.1101/2024.02.25.581948 — cancer biology — Posted on 2024-02-28
370 Bioactive coatings on 3D printed scaffolds for bone regeneration: Use of Laponite(R) to deliver BMP-2 in an ovine femoral condyle defect model
Marshall, K. M.; McLaren, J. S.; Wojciechowski, J. P.; Callens, S. J. P.; Echalier, C.; Kanczler, J. M.; Rose, F. R. A. J.; Stevens, M. M.; Dawson, J. I.; Oreffo, R. O. C.
10.1101/2024.02.25.581921 — bioengineering — Posted on 2024-02-28
371 Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer cells
Buglakova, E.; Ekelöf, M.; Schwaiger-Haber, M.; Schlicker, L.; Molenaar, M. R.; Mohammed, S.; Stuart, L.; Eisenbarth, A.; Hilsenstein, V.; Patti, G.; Schulze, A.; Snaebjornsson, M.; Alexandrov, T.
10.1101/2023.08.18.553810 — biochemistry — Posted on 2024-02-28
374 Neuronal and behavioral responses to naturalistic texture images in macaque monkeys
Ziemba, C. M.; Goris, R. L. T.; Stine, G. M.; Perez, R. K.; Simoncelli, E. P.; Movshon, J. A.
10.1101/2024.02.22.581645 — neuroscience — Posted on 2024-02-28
375 Metabolic control of adaptive β-cell proliferation by the protein deacetylase SIRT2
Wortham, M.; Ramms, B.; Zeng, C.; Benthuysen, J. R.; Sai, S.; Pollow, D. P.; Liu, F.; Schlichting, M.; Harrington, A. R.; Liu, B.; Prakash, T. P.; Pirie, E. C.; Zhu, H.; Baghdasarian, S.; Auwerx, J.; Shirihai, O. S.; Sander, M.
10.1101/2024.02.24.581864 — physiology — Posted on 2024-02-28
377 Schlafen-11 and -9 are innate immune sensors for intracellular single-stranded DNA
Liu, D.; Zhang, P.; Hu, X.; Li, Z.; Liu, S.; Jin, Y.; Wang, J.; Chen, H.; Hao, D.; Zhao, X.; Liu, L.; Liu, Q.
10.1101/2024.02.24.581893 — immunology — Posted on 2024-02-28
378 A VHL-1/HIF-1/SQRD1/COL-88 axis links extracellular matrix formation with longevity in Caenorhabditis elegans
Salgueiro, W.; Esmaillie, R.; Bohl, K.; Statzer, C.; Bharill, P.; Bargfrede, S.; Chokkalingam, M.; Neutzer, M.; Ignarski, M.; Benzing, T.; Beyer, A.; Schermer, B.; Ewald, C.; Fabretti, F.; Müller, R.-U.
10.1101/2024.02.22.581513 — genetics — Posted on 2024-02-28
379 The Ubiquitin Ligase RBX2/SAG Regulates Mitochondrial Ubiquitination and Mitophagy
Wang, W.; Li, E.; Zou, J.; Qu, C.; Ayala, J.; Wen, Y.; Islam, M. S.; Weintraub, N. L.; Fulton, D. J.; Liang, Q.; Zhou, J.; Liu, J.; Li, J.; Sun, Y.; Su, H.
10.1101/2024.02.24.581168 — pathology — Posted on 2024-02-28
381 cMPL-Based Purification and Depletion of Human Hematopoietic Stem Cells: Implications for Pre-Transplant Conditioning
Araki, D.; Hong, S.; Linde, N.; Fisk, B.; Redekar, N.; Salisbury-Ruf, C.; Krouse, A.; Engels, T.; Golomb, J.; Dagur, P.; Magnani, D. M.; Wang, Z.; Larochelle, A.
10.1101/2024.02.24.581887 — cell biology — Posted on 2024-02-28
382 Dietary bacteria controls C. elegans lipid metabolism through pathways converging at phosphatidylcholine
Han, H.; Nien, S.-F.; Jiang, H.-S.; Wu, J.-C.; Chiang, C.-Y.; Li, M.-T.; Huang, L.-J.; Chiang, S.; Lin, L.-C.; Chuang, Y.-T.; Lin, Y.-H.; Wang, C.-W.; Wu, Y.-C.
10.1101/2024.02.24.581900 — cell biology — Posted on 2024-02-28
383 Male and female variability in response to chronic stress and morphine in C57BL/6J, DBA/2J, and their BXD progeny
Morel, C.; Parise, L. F.; Van der Zee, Y.; Issler, O.; Cai, M.; Browne, C. J.; Blando, A.; LeClair, K. B.; Hayes, S.; Williams, R. W.; Mulligan, M. K.; Nestler, E. J.; Russo, S.; Han, M.-H.
10.1101/2024.02.23.581795 — neuroscience — Posted on 2024-02-28
384 Genetic and physical interactions reveal overlapping and distinct contributions to meiotic double-strand break formation in C. elegans
Raices, M.; Balmir, F.; Silva, N.; Li, W.; Grundy, M. K.; Hoffman, D. K.; Altendorfer, E.; Camacho, C. J.; Bernstein, K.; Colaiacovo, M. P.; Yanowitz, J.
10.1101/2024.02.23.581796 — developmental biology — Posted on 2024-02-28
385 Kir6.2-KATP channels alter glycolytic flux to modulate cortical activity, arousal, and sleep-wake homeostasis
Constantino, N. J.; Carroll, C. M.; Williams, H. C.; Yuede, C. M.; Sheehan, P. W.; Snipes, J. A.; Musiek, E. S.; Johnson, L. A.; Macauley, S. L.
10.1101/2024.02.23.581817 — neuroscience — Posted on 2024-02-28
386 Wake EEG oscillation dynamics reflect both sleep need and brain maturation across childhood and adolescence
Snipes, S.; Krugliakova, E.; Jaramillo, V.; Volk, C.; Furrer, M.; Studler, M.; LeBourgeois, M.; Kurth, S.; Jenni, O. G.; Huber, R.
10.1101/2024.02.24.581878 — neuroscience — Posted on 2024-02-28
387 Multimodal histopathologic models stratify hormone receptor-positive early breast cancer
Boehm, K. M.; El Nahhas, O. S. M.; Marra, A.; Selenica, P.; Wen, H. Y.; Weigelt, B.; Paul, E. D.; Cekan, P.; Erber, R.; Loeffler, C. M. L.; Guerini-Rocco, E.; Fusco, N.; Frascarelli, C.; Mane, E.; Munzone, E.; Dellapasqua, S.; Zagami, P.; Curigliano, G.; Razavi, P.; Reis-Filho, J. S.; Pareja, F.; Chandarlapaty, S.; Shah, S. P.; Kather, J. N.
10.1101/2024.02.23.581806 — pathology — Posted on 2024-02-28
388 Efficient and reproducible generation of human iPSC-derived cardiomyocytes using a stirred bioreactor
Prondzynski, M.; Bortolin, R. H.; Berkson, P.; Trembley, M. A.; Shani, K.; Sweat, M. E.; Mayourian, J.; Anyanwu, N. J.; Cordoves, A. M.; Tharani, Y.; Cotton, J.; Milosh, J. B.; Walker, D.; Zhang, Y.; Lu, F.; Liu, X.; Parker, K. K.; Bezzerides, V. J.; Pu, W. T.
10.1101/2024.02.24.581789 — cell biology — Posted on 2024-02-28
392 Late-Life Alcohol Exposure Does Not Exacerbate Age-Dependent Reductions in Mouse Spatial Memory and Brain TFEB Activity
Chen, H.; Hinz, K.; Zhang, C.; Rodriguez, Y.; Williams, S. N.; Niu, M.; Ma, X.; Chao, X.; Frazier, A. L.; McCarson, K. E.; Wang, X.; Peng, Z.; Liu, W.; Ni, H.-M.; Zhang, J.; Swerdlow, R. H.; Ding, W.-X.
10.1101/2024.02.23.581774 — animal behavior and cognition — Posted on 2024-02-28
394 Quorum-sensing agr system of Staphylococcus aureus primes gene expression for protection from lethal oxidative stress
Podkowik, M.; Perault, A. I.; Putzel, G.; Pountain, A.; Kim, J.; DuMont, A.; Zwack, E.; Ulrich, R. J.; Karagounis, T. K.; Zhou, C.; Haag, A. F.; Shenderovich, J.; Wasserman, G. A.; Kwon, J.; Chen, J.; Richardson, A. R.; Weiser, J. N.; Nowosad, C. R.; Lun, D. S.; Zhao, X.; Parker, D.; Pironti, A.; Drlica, K. N.; Yanai, I.; Torres, V. J.; Shopsin, B.
10.1101/2023.06.08.544038 — microbiology — Posted on 2024-02-28
395 Rhesus Cytomegalovirus-encoded Fcγ-binding glycoproteins facilitate viral evasion from IgG-mediated humoral immunity
Otero, C. E.; Petkova, S.; Ebermann, M.; Taher, H.; John, N.; Hoffmann, K.; Davalos, A.; Mostrom, M. J.; Gilbride, R. M.; Papen, C.; Barber-Axthelm, A.; Scheef, E. A.; Barfield, R.; Sprehe, L. M.; Kendall, S.; Manuel, T. D.; Vande Burgt, N.; Chan, C.; Streblow, D. N.; Hansen, S. G.; Denton, M.; Streblow, Z.; Kaur, A.; Permar, S. R.; Frueh, K.; Hengel, H.; Malouli, D.; Kolb, P.
10.1101/2024.02.27.582371 — microbiology — Posted on 2024-02-28
396 Mating-compatibility genes employed as diagnostic markers to identify novel incursions of the myrtle rust pathogen Austropuccinia psidii
Feng, J.; Bird, A.; Luo, Z.; Tam, R.; Shepherd, L.; Murphy, L.; Singh, L.; Graetz, A.; Moeller, M.; Amorim, L.; Massola Junior, N. S.; Prodhan, M. A.; Shuey, L.; Beattie, D.; Gonzalez, A. T.; Tobias, P. A.; Padovan, A.; Kimber, R.; McTaggart, A.; Kehoe, M.; Schwessinger, B.; Boufleur, T. R.
10.1101/2024.02.19.580897 — plant biology — Posted on 2024-02-28
397 MutationExplorer - a webserver for mutation of proteins and 3D visualization of energetic impacts
Philipp, M.; Moth, C. W.; Ristic, N.; Tiemann, J. K. S.; Seufert, F.; Panfilova, A.; Meiler, J.; Hildebrand, P.-W.; Stein, A.; Wiegreffe, D.; Staritzbichler, R.
10.1101/2023.03.23.533926 — bioinformatics — Posted on 2024-02-28
399 Large-scale characterization of cell niches in spatial atlases using bio-inspired graph learning
Birk, S.; Bonafonte-Pardas, I.; Feriz, A. M.; Boxall, A.; Agirre, E.; Memi, F.; Maguza, A.; Fan, R.; Castelo-Branco, G.; Bayraktar, O.; Theis, F. J.; Talavera-Lopez, C.; Lotfollahi, M.
10.1101/2024.02.21.581428 — bioinformatics — Posted on 2024-02-28
400 Thermal acclimation of stem respiration reduces global carbon burden
Zhang, H.; Wang, H.; Wright, I. J.; Prentice, C.; Harrison, S. P.; Smith, N. G.; Westerband, A.; Rowland, L.; Plavcova, L.; Morris, H.; Reich, P. B.; Jansen, S.; Keenan, T.
10.1101/2024.02.23.581610 — ecology — Posted on 2024-02-28
401 Fifty Years After: The N1 Effect Travels Down to the Brainstem
Strauss, D. J.; Corona-Strauss, F. I.; Mai, A.; Hillyard, S. A.
10.1101/2024.02.23.581747 — neuroscience — Posted on 2024-02-28
406 Transcriptomic signature and pro-osteoclastic secreted factors of abnormal bone marrow stromal cells in fibrous dysplasia
Michel, Z.; Raborn, L. N.; Spencer, T.; Pan, K. S.; Martin, D.; Roszko, K. L.; Wang, Y.; Robey, P.; Boyce, A.; Collins, M. T.; de Castro, L. F.
10.1101/2024.02.23.581225 — pathology — Posted on 2024-02-28
412 A half-centre oscillator encodes sleep pressure
Hasenhuetl, P. S.; Sarnataro, R.; Vrontou, E.; Rorsman, H. O.; Talbot, C. B.; Brain, R.; Miesenboeck, G.
10.1101/2024.02.23.581780 — neuroscience — Posted on 2024-02-28
413 A generative model of the connectome with dynamic axon growth
Liu, Y.; Seguin, C.; Betzel, R. F.; Akarca, D.; Di Biase, M. A.; Zalesky, A.
10.1101/2024.02.23.581824 — neuroscience — Posted on 2024-02-28
414 Active filtering of sequences of neural activity by recurrent circuits of sensory cortex
Deveau, C.; Zhou, Z.; LaFosse, P. K.; Deng, Y.; Mirbagheri, S.; Steinmetz, N.; Histed, M. H.
10.1101/2024.02.24.581890 — neuroscience — Posted on 2024-02-28
415 The transcriptional response of cortical neurons to concussion reveals divergent fates after injury
Alkaslasi, M. R.; Lloyd, E. Y. H.; Gable, A. S.; Silberberg, H.; Yarur, H. E.; Tsai, V. S.; Tejeda, H. A.; Le Pichon, C. E.
10.1101/2024.02.26.581939 — neuroscience — Posted on 2024-02-28
418 Quantification of sporozoite expelling by Anopheles mosquitoes infected with laboratory and naturally circulating P. falciparum gametocytes
Andolina, C.; Graumans, W.; Guelbeogo, M.; Gemert, G.-J. v.; Ramjith, J.; Harouna, S.; Soumanaba, Z.; Stoter, R.; van de Vegte-Bolmer, M.; Pangos, M.; Sinnis, P.; Collins, K.; Staedke, S.; Tiono, A.; Drakeley, C.; Lanke, K.; Bousema, T.
10.1101/2023.08.03.551751 — microbiology — Posted on 2024-02-28
421 Extended blood stage sensitivity profiles of Plasmodium vivax to doxycycline and tafenoquine using Plasmodium cynomolgi as a model
Christensen, P.; Cinzah, R.; Suwanarusk, R.; Chua, A. C. Y.; Kaneko, O.; Kyle, D. E.; Aung, H. L.; Matheson, J.; Bifani, P.; Renia, L.; Cook, G. M.; Snounou, G.; Russell, B. M.
10.1101/2024.02.23.581752 — microbiology — Posted on 2024-02-28
423 An ancient ecospecies of Helicobacter pylori found in Indigenous populations and animal adapted lineages.
Tourrette, E.; Torres, R. C.; Svensson, S. L.; Matsumoto, T.; Fauzia, K. A.; Alfaray, R. I.; Vilaichone, R.-K.; Tuan, V. P.; HelicobacterGenomicsConsortium, ; Wang, D.; Olsson, L.; Yadegar, A.; Zhou, Z.; Yamaoka, Y.; Thorell, K.; Falush, D.
10.1101/2023.04.28.538659 — microbiology — Posted on 2024-02-28
424 Metabolic reprogramming of hypoxic tumour-associated macrophages through CSF-1R targeting favours treatment efficiency in colorectal cancers
Gharzeddine, K.; Gonzales Pietro, C.; Malier, M.; Hennot, C.; Grespan, R.; Yamaryo, Y.; Botte, C.; Thomas, F.; Laverriere, M. H.; Girard, E.; Roth, G.; MILLET, A.
10.1101/2024.02.22.581558 — immunology — Posted on 2024-02-28
426 Sensory neuron population expansion enhances odor tracking without sensitizing projection neurons
Takagi, S.; Sancer, G.; Abuin, L.; Stupski, S. D.; Arguello, J. R.; Prieto-Godino, L. L.; Stern, D. L.; Cruchet, S.; Alvarez-Ocana, R.; Wienecke, C. F. R.; van Breugel, F.; Jeanne, J. M.; Auer, T. O.; Benton, R.
10.1101/2023.09.15.556782 — neuroscience — Posted on 2024-02-28
434 Propionyl-CoA carboxylase subunit B regulates anti-tumor T cells in a pancreatic cancer mouse model
Han, H. V.; Efem, R.; Rosati, B.; Lu, K.; Maimouni, S.; Jiang, Y.-P.; Montoya, V.; Van Der Velden, A.; Zong, W.-X.; Lin, R. Z.
10.1101/2023.07.24.550301 — cancer biology — Posted on 2024-02-28
435 Enhancer landscape of lung neuroendocrine tumors reveals regulatory and developmental signatures with potential theranostic implications
Davis, E.; Avniel-Polak, S.; Abu-Kamel, S.; Antman, I.; Saadoun, T.; Brim, C.; Bel-Ange, A.; Atlan, K.; Tzur, T.; Abu-Akar, F.; Wald, O.; Izhar, U.; Hecht, M.; Grozinsky-Glasberg, S.; Drier, Y.
10.1101/2023.11.17.566871 — cancer biology — Posted on 2024-02-28
439 Overcoming the nutritional immunity by engineering iron scavenging bacteria for cancer therapy
Huang, S.-W.; Lim, S.-K.; Yu, Y.-A.; Pan, Y.-C.; Lien, W.-J.; Mou, C.-Y.; Hu, C.-M. J.; Mou, K. Y.
10.1101/2023.07.25.550605 — bioengineering — Posted on 2024-02-28
440 Cdc13 exhibits dynamic DNA strand exchange in the presence of telomeric DNA
Nickens, D. G.; Feng, Z.; Shen, J.; Gray, S. J.; Simmons, R. H.; Niu, H.; Bochman, M. L.
10.1101/2023.12.04.569902 — biochemistry — Posted on 2024-02-28
442 A harmonized public resource of deeply sequenced diverse human genomes
Koenig, Z.; Yohannes, M. T.; Nkambule, L. L.; Zhao, X.; Goodrich, J. K.; Kim, H. A.; Wilson, M. W.; Tiao, G.; Hao, S. P.; Sahakian, N.; Chao, K. R.; Walker, M. A.; Lyu, Y.; gnomAD Project Consortium, ; Rehm, H.; Neale, B.; Talkowski, M. E.; Daly, M. J.; Brand, H.; Karczewski, K.; Atkinson, E. G.; Martin, A.
10.1101/2023.01.23.525248 — genomics — Posted on 2024-02-28
448 The Arthropoda-specific Tramtrack group BTB protein domains use previously unknown interface to form hexamers
Bonchuk, A.; Balagurov, K.; Baradaran, R.; Boyko, K.; Sluchanko, N. N.; Khrustaleva, A.; Burtseva, A.; Arkova, O.; Khalisova, K.; Popov, V.; Naschberger, A.; Georgiev, P.
10.1101/2022.09.01.506177 — molecular biology — Posted on 2024-02-28
449 Characterisation of RNA editing and gene therapy with a compact CRISPR-Cas13 in the retina
Kumar, S.; Hsiao, Y.-W.; Wong, V. H. Y.; Aubin, D.; Wang, J.-H.; Lisowski, L.; Rakoczy, E. P.; Li, F.; Alarcon-Martinez, L.; Gonzalez Cordero, A.; Bui, B. V.; Liu, G.-S.
10.1101/2024.02.10.579778 — molecular biology — Posted on 2024-02-28
451 Distinct microcolony morphologies promote flow-dependent bacterial colonization
Hallinen, K. M.; Bodine, S. P.; Stone, H. A.; Muir, T. W.; Wingreen, N. S.; Gitai, Z.
10.1101/2023.11.22.568348 — microbiology — Posted on 2024-02-28
452 Cell class-specific electric field entrainment of neural activity
Lee, S. Y.; Kozalakis, K.; Baftizadeh, F.; Campagnola, L.; Jarsky, T.; Koch, C.; Anastassiou, C. A.
10.1101/2023.02.14.528526 — neuroscience — Posted on 2024-02-28
453 Genetic mapping identifies Homer1 as a developmental modifier of attention
Gershon, Z. Z.; Bonito-Oliva, A.; Kanke, M.; Terceros, A.; Rankin, G.; Fak, J.; Harada, Y.; Iannone, A. F.; Gebrehemedin, M.; Fabella, B.; De Marco Garcia, N.; Sethupathy, P.; Rajasethupathy, P.
10.1101/2023.03.17.533136 — neuroscience — Posted on 2024-02-28
456 Neural Trajectories of Conceptually Related Events
Schafer, M.; Kamilar-Britt, P.; Sahani, V.; Bachi, K.; Schiller, D.
10.1101/2023.12.04.569670 — neuroscience — Posted on 2024-02-28
457 Mitochondrial complex I deficiency stratifies idiopathic Parkinson's disease
Flones, I.; Toker, L.; Sandnes, D. A.; Castelli, M.; Mostafavi, S.; Lura, N.; Shadad, O.; Fernandez-Vizarra, E.; Painous, C.; Perez-Soriano, A.; Compta, Y.; Molina-Porcel, L.; Alves, G.; Tysnes, O.-B.; Dolle, C.; Nido, G. S.; Tzoulis, C.
10.1101/2023.09.22.558615 — neuroscience — Posted on 2024-02-28
461 Accelerated signal propagation speed in human neocortical microcircuits
Olah, G.; Lakovics, R.; Shapira, S.; Leibner, Y.; Szucs, A.; Csajbok, E. A.; Barzo, P.; Molnar, G.; Segev, I.; Tamas, G.
10.1101/2022.09.30.510270 — neuroscience — Posted on 2024-02-28
465 Network Statistics of the Whole-Brain Connectome of Drosophila
Lin, A.; Yang, R.; Dorkenwald, S.; Matsliah, A.; Sterling, A. R.; Schlegel, P.; Yu, S.-c.; McKellar, C. E.; Costa, M.; Eichler, K.; Bates, A. S.; Eckstein, N.; Funke, J.; Jefferis, G. S. X. E.; Murthy, M.
10.1101/2023.07.29.551086 — neuroscience — Posted on 2024-02-28
466 Feedforward and disinhibitory circuits differentially control activity of cortical somatostatin-positive interneurons during behavioral state transitions
De Brito Van Velze, M.; Dhanasobhon, D.; Martinez, M.; Morabito, A.; Berthaux, E.; Martins Pinho, C.; Rebola, N.; Zerlaut, Y.
10.1101/2024.01.10.574973 — neuroscience — Posted on 2024-02-28
469 Large library docking for cannabinoid-1 receptor agonists with reduced side effects
Tummino, T. A.; Iliopoulos-Tsoutsouvas, C.; Braz, J. M.; O'Brien, E. S.; Stein, R. M.; Craik, V.; Tran, N. K.; Ganapathy, S.; Liu, F.; Shiimura, Y.; Tong, F.; Ho, T. C.; Radchenko, D. S.; Moroz, Y. S.; Rosado, S. R.; Bhardwaj, K.; Benitez, J.; Liu, Y.; Kandasamy, H.; Normand, C.; Semache, M.; Sabbagh, L.; Glenn, I.; Irwin, J. J.; Kumar, K. K.; Makriyannis, A.; Basbaum, A. I.; Shoichet, B. K.
10.1101/2023.02.27.530254 — pharmacology and toxicology — Posted on 2024-02-28
472 KSR1 regulates small-cell lung carcinoma tumor initiation and therapy resistance
Chatterjee, D.; Svoboda, R. A.; Huisman, D. H.; Vieira, H. M.; Rao, C.; Askew, J. W.; Fisher, K. W.; Lewis, R. E.
10.1101/2024.02.23.581815 — cancer biology — Posted on 2024-02-28
477 Engineering an Escherichia coli strain for production of long single-stranded DNA
Shen, K.; Flood, J. J.; Zhang, Z.; Ha, A.; Shy, B.; Dueber, J. E.; Douglas, S. M.
10.1101/2024.02.27.582394 — bioengineering — Posted on 2024-02-27
478 Versatile Functional Interaction between Electrically Silent KV Subunits and KV7 Potassium Channels
Renigunta, V. K.; Xhaferri, N.; Shaikh, I. G.; Schlegel, J.; Bisen, R.; Sanvido, I.; Kalpachidou, T.; Kummer, K.; Oliver, D.; Leitner, M. G.; Lindner, M.
10.1101/2024.02.23.581732 — neuroscience — Posted on 2024-02-27
479 Meningioma transcriptomic landscape demonstrates novel subtypes with regional associated biology and patient outcome.
Thirimanne, H. N.; Bonnin, D. A.; Nuechterlein, N.; Arora, S.; Jensen, M.; Parada, C. A.; Qiu, C.; Szulzewsky, F.; English, C. W.; Chen, W. C.; Sievers, P.; Nassiri, F.; Wang, J. Z.; Klisch, T. J.; Aldape, K. D.; Patel, A. J.; Cimino, P. J.; Zadeh, G.; Sahm, F.; Raleigh, D. R.; Shendure, J.; Ferreira, M.; Holland, E. C.
10.1101/2024.02.23.581766 — cancer biology — Posted on 2024-02-27
481 Ribonanza: deep learning of RNA structure through dual crowdsourcing
He, S.; Huang, R.; Townley, J.; Kretsch, R. C.; Karagianes, T. G.; Cox, D. B. T.; Blair, H.; Penzar, D.; Vyaltsev, V.; Aristova, E.; Zinkevich, A.; Bakulin, A.; Sohn, H.; Krstevski, D.; Fukui, T.; Tatematsu, F.; Uchida, Y.; Jang, D.; Lee, J. S.; Shieh, R.; Ma, T.; Martynov, E.; Shugaev, M. V.; Bukhari, H. S. T.; Fujikawa, K.; Onodera, K.; Henkel, C.; Ron, S.; Romano, J.; Nicol, J. J.; Nye, G. P.; Wu, Y.; Choe, C.; Reade, W.; Eterna participants, ; Das, R.
10.1101/2024.02.24.581671 — biophysics — Posted on 2024-02-27
483 Identification of Thioredoxin1 interacting proteins in neuronal cytoskeletal organization during autophagy
Islam, M. I.; Sultana, S.; Padmanabhan, N.; Rashid, M.-u.; Siddiqui, T.; Coombs, K.; Vitiello, P.; Karimi, S.; Eftekharpour, E.
10.1101/2024.02.27.582366 — biochemistry — Posted on 2024-02-27
485 Matching Excellence: ONT's Rise to Parity with PacBio in Genome Reconstruction of Non-Model Bacterium with High GC Content
Soto Serrano, A.; Li, W.; Panah, F.; Hui, Y.; Atienza, P.; Fomenkov, A.; Roberts, R. J.; Deptula, P.; Krych, L.
10.1101/2024.02.26.582104 — genomics — Posted on 2024-02-27
486 Integrative genomics sheds light on the immunobiology of tuberculosis in cattle
O'Grady, J. F.; McHugo, G. P.; Ward, J. A.; Hall, T. J.; Faherty O'Donnell, S. L.; Correia, C. N.; Browne, J. A.; McDonald, M.; Gormley, E.; Riggio, V.; Prendergast, J. G. D.; Clark, E. L.; Pausch, H.; Meade, K. G.; Gormley, I. C.; Gordon, S. V.; MacHugh, D. E.
10.1101/2024.02.27.582295 — genomics — Posted on 2024-02-27
489 The Mayo Clinic Salivary Tissue-Organoid Biobanking: A Resource for Salivary Regeneration Research
Aalam, S. M. M.; Varela, A. R.; Khaderi, A.; Mondesir, R. J.; Mun, D.-G.; Ding, A. Z.; Lombaert, I. M. A.; Coppes, R. P.; Emperumal, C. P.; Pandey, A.; Janus, J. R.; Kannan, N.
10.1101/2024.02.23.581761 — cell biology — Posted on 2024-02-27
490 A multi-looping chromatin signature predicts dysregulated gene expression in neurons with familial Alzheimer's disease mutations
Chandrashekar, H.; Simandi, Z.; Choi, H.; Ryu, H.-S.; Waldman, A. J.; Nikish, A.; Muppidi, S. S.; Gong, W.; Paquet, D.; Phillips-Cremins, J. E.
10.1101/2024.02.27.582395 — molecular biology — Posted on 2024-02-27
491 Essential functions of Inositol hexakisphosphate (IP6) in Murine Leukemia Virus replication
Biswas, B.; Lai, K. K.; Bracey, H.; Datta, S. A. K.; Harvin, D.; Sowd, G. A.; Aiken, C.; Rein, A.
10.1101/2024.02.27.581940 — molecular biology — Posted on 2024-02-27
494 Profound synthetic lethality between SMARCAL1 and FANCM
Feng, S.; Liu, K.; Shang, J.; Hoeg, L.; Yang, W.; Roy, S.; Young, J. T.; Wu, W.; Xu, D.; Durocher, D.
10.1101/2024.02.27.582393 — molecular biology — Posted on 2024-02-27
495 A versatile reporter system to study cell-to-cell and cell-free bovine leukemia virus infection
Rammauro, F.; Flo, M.; Carrion, F.; Ortega, C.; Di Nunzio, F.; Vallmitjana, A.; Pritsch, O.; Olivero, N.
10.1101/2024.02.26.581980 — microbiology — Posted on 2024-02-27
497 A Caenorhabditis elegans based system for high-throughput functional phenotyping of human gut microbiota
Ambat, A.; Thayyil Valappil, V.; Ghimire, S.; Harnvoravongchai, P.; Mishra, S.; Vijayan Pillai, V.; Kashyap, P.; Scaria, J.
10.1101/2024.02.27.582212 — microbiology — Posted on 2024-02-27
498 Emergence of bluetongue virus serotype 3 in western Germany, October 2023, and ad-hoc monitoring in Culicoides biting midges
Voigt, A.; Kampen, H.; Heuser, E.; Zeiske, S.; Hoffmann, B.; Hoeper, D.; Holsteg, M.; Sick, F.; Ziegler, S.; Wernike, K.; Beer, M.; Werner, D.
10.1101/2024.02.26.582175 — microbiology — Posted on 2024-02-27
500 Evaluating treatments for the protection of grapevine pruning wounds from natural infection by trunk disease fungi
Leal, C.; Bujanda, R.; Manzanares, B. L.; Ojeda, S.; Berbegal, M.; Llop, A. V.; Santesteban, L. G.; Palacios, J.; Gramaje, D.
10.1101/2024.02.27.582328 — microbiology — Posted on 2024-02-27
501 Single-cell approach dissecting agr quorum sensing dynamics in Staphylococcus aureus
Baer, J.; Charlton, S. G. V.; Tarnutzer, A.; Ugolini, G. S.; Secchi, E.; Zinkernagel, A. S.
10.1101/2024.02.27.582246 — microbiology — Posted on 2024-02-27
503 TISSUE-SPECIFIC METABOLOMIC REPROGRAMMING DETERMINES THE DISEASE PATHOPHYSIOLOGY OF SARS-COV-2 VARIANTS IN HAMSTER MODEL
Sardarni, U. K.; Ambikan, A.; Acharya, A.; Johnson, S. D.; Avedissian, S. N.; Vegvari, A.; Neogi, U.; Byrareddy, S.
10.1101/2024.02.25.581989 — systems biology — Posted on 2024-02-27
504 SIGNAL-seq: Multimodal Single-cell Inter- and Intra-cellular Signalling Analysis
Opzoomer, J. W.; O'Sullivan, R.; Sufi, J.; Madsen, R. R.; Qin, X.; Basiarz, E.; Tape, C. J.
10.1101/2024.02.23.581433 — cancer biology — Posted on 2024-02-27
505 CapP mediates the structural formation of biofilm-specific pili in the opportunistic human pathogen Bacillus cereus
Alvarez-Mena, A.; Shukkoor, M. B. A.; Caro-Astorga, J.; Berbon, M.; Gomez, M. L. A.; Grelard, A.; Kauffmann, B.; Morvan, E.; de Vicente, A.; Loquet, A.; Romero, D.
10.1101/2024.02.27.582368 — microbiology — Posted on 2024-02-27
506 Establishment of an Inhalation Administration Noninvasive Murine Model for Rapidly Testing Drug Activity against Mycobacterium tuberculosis
Tian, X.; Gao, Y.; Ma, W.; Zhang, J.; Ju, Y.; Ding, J.; Zeng, S.; Hameed, A.; Zhong, N.; Cook, G. M.; Hu, J.; zhang, T.
10.1101/2024.02.27.582260 — microbiology — Posted on 2024-02-27
508 Nitrogen cycling during an Arctic bloom: from chemolithotrophy to nitrogen assimilation
Laso Perez, R.; Rivas Santisteban, J.; Fernandez-Gonzalez, N.; Mundy, C. J.; Tamames, J.; Pedros-Alio, C.
10.1101/2024.02.27.582273 — microbiology — Posted on 2024-02-27
509 Spatial control of sensory adaptation modulates mechanosensing in Pseudomonas aeruginosa
Patino, R.; Kuhn, M. J.; Macmillan, H.; Inclan, Y.; Chavez, I.; Von Dollen, J.; Johnson, J. R.; Swaney, D. L.; Krogan, N.; Persat, A.; Engel, J.
10.1101/2024.02.27.582188 — microbiology — Posted on 2024-02-27
511 Coordination between cytoskeletal organization, cell contraction and extracellular matrix development, is depended on LOX for aneurysm prevention
Hasson, P.; Aviram, R.; Zaffryar-Eilot, S.; Kaganovsky, A.; Odeh, A.; Melamed, S.; Militsin, R.; Pinnock, C. B.; Shemesh, A.; Palty, R.; Ganesh, S. K.
10.1101/2024.02.23.581837 — cell biology — Posted on 2024-02-27
512 Rhesus Cytomegalovirus-encoded Fcγ-binding glycoproteins facilitate viral evasion from IgG-mediated humoral immunity
Otero, C. E.; Petkova, S.; Ebermann, M.; Taher, H.; John, N.; Hoffmann, K.; Davalos, A.; Mostrom, M. J.; Gilbride, R. M.; Papen, C.; Barber-Axthelm, A.; Scheef, E. A.; Barfield, R.; Sprehe, L. M.; Kendall, S.; Manuel, T. D.; Vande Burgt, N.; Chan, C.; Streblow, D. N.; Hansen, S. G.; Denton, M.; Streblow, Z.; Kaur, A.; Permar, S. R.; Frueh, K.; Hengel, H.; Malouli, D.; Kolb, P.
10.1101/2024.02.27.582371 — microbiology — Posted on 2024-02-27
513 Sequence modeling and design from molecular to genome scale with Evo
Nguyen, E.; Poli, M.; Durrant, M. G.; Thomas, A. W.; Kang, B.; Sullivan, J.; Ng, M. Y.; Lewis, A.; Patel, A.; Lou, A.; Ermon, S.; Baccus, S. A.; Hernandez-Boussard, T.; Re, C.; Hsu, P. D.; Hie, B. L.
10.1101/2024.02.27.582234 — synthetic biology — Posted on 2024-02-27
515 Development and validation of a gene expression score to account for tumour purity and improve prognostication in breast cancer
Barreca, M.; Dugo, M.; Galbardi, B.; Gyorrfy, B.; NA-PHER2 consortium, ; NeoTRIP consortium, ; Valagussa, P.; Besozzi, D.; Viale, G.; Bianchini, G.; Gianni, L.; Callari, M.
10.1101/2024.02.23.581701 — bioinformatics — Posted on 2024-02-27
520 Yerba mate (Ilex paraguariensis) genome provides new insights into convergent evolution of caffeine biosynthesis
Vignale, F. A.; Hernandez Garcia, A.; Modenutti, C. P.; Sosa, E. J.; Defelipe, L. A.; Oliveira, R. R. M.; Nunes, G. L.; Acevedo, R. M.; Burguener, G. F.; Rossi, M.; Zapata, P. D.; Marti, D. A.; Sansberro, P. A.; Oliveira, G.; Smith, M. N.; Dubs, N. M.; Nair, S.; Barkman, T. J.; Turjanski, A. G.
10.1101/2023.09.08.556846 — plant biology — Posted on 2024-02-27
521 The MODY-associated KCNK16 L114P mutation increases islet glucagon secretion and limits insulin secretion resulting in transient neonatal diabetes and glucose dyshomeostasis in adults
Nakhe, A. Y.; Dadi, P. K.; Kim, J.; Dickerson, M. T.; Behera, S.; Dobson, J. R.; Shrestha, S.; Cartailler, J.-P.; Sampson, L.; Magnuson, M. A.; Jacobson, D. A.
10.1101/2023.06.20.545631 — physiology — Posted on 2024-02-27
523 MICROCOSM FABRICATION PLATFORM FOR LIVE MICROSCOPY OF PLANT-SOIL SYSTEMS
Liu, Y.; Patko, D.; de le Mata, A. L.; Dong, X.; Peral, E. G.; He, X.; Ameduri, B.; Ladmiral, V.; MacDonald, M. P.; Dupuy, L. X.
10.1101/2024.02.23.581454 — bioengineering — Posted on 2024-02-27
524 Woman the Hunter? Female foragers sometimes hunt, yet gendered divisions of labor are real
Venkataraman, V. V.; Hoffman, J.; Hames, R. B.; Stibbard-Hawkes, D. N. E.; Kramer, K.; Kelly, R.; Farquharson, K.; Hagen, E. H.; Hewlett, B. S.; DAvis, H. E.; Glowacki, L.; Jang, H.; Syne, K.; Starkweather, K.; Lew-Levy, S.
10.1101/2024.02.23.581721 — evolutionary biology — Posted on 2024-02-27
525 Stereotyped cell lineage trees support robust development
Zhang, X.; Li, Z.; Chen, J.; Yang, W.; Wu, P.; Chen, F.; He, X.; Chen, X.; Yang, J.-R.
10.1101/2024.02.23.581522 — developmental biology — Posted on 2024-02-27
526 Regulation of defense strategies and host metabolism to survive neonatal infection
Wu, Z.; Tien, N. T. N.; Baek, O.; Zhong, J.; Klabunde, B.; Yen, N. T. H.; Long, N. P.; Nguyen, D. N.
10.1101/2024.02.23.581534 — immunology — Posted on 2024-02-27
529 What Does Large-scale Electrodermal Sensing Reveal?
McDuff, D.; Thomson, S.; Abdel-Ghaffar, S.; Galatzer-Levy, I.; Poh, M.-Z.; Sunshine, J.; Barakat, A.; Heneghan, C.; Sunden, L.
10.1101/2024.02.22.581472 — physiology — Posted on 2024-02-27
530 Directed biomechanical compressive forces enhance fusion efficiency in model placental trophoblast cultures
Parameshwar, P. K.; Li, C.; Arnauts, K.; Jiang, J.; Rostami, S.; Campbell, B. E.; Lu, H.; Rosenzweig, D. H.; Vaillancourt, C.; Moraes, C.
10.1101/2024.02.22.581638 — biophysics — Posted on 2024-02-27
531 A Multi-Omics Atlas of Sex-Specific Differences in Obstructive Hypertrophic Cardiomyopathy
Garmany, R.; Dasari, S.; Bos, J. M.; Kim, E. T.; Martinez, K. A.; Tester, D. J.; dos Remedios, C.; Maleszewski, J. J.; Dearani, J. A.; Ommen, S. R.; Geske, J. B.; Guidicessi, J. R.; Ackerman, M. J.
10.1101/2024.02.22.581621 — bioinformatics — Posted on 2024-02-27
533 CloVarS: a simulation of single-cell clonal variability
Faccioni, J. L.; Buss, J. H.; Begnini, K. R.; Brunnet, L. G.; Oliveira, M. M.; Lenz, G.
10.1101/2024.02.22.581631 — bioinformatics — Posted on 2024-02-27
538 Reference curves for harmonizing multi-site regional diffusion MRI metrics across the lifespan
Zhu, A. H.; Nir, T. M.; Javid, S.; Villalon-Reina, J. E.; Rodrigue, A. L.; Strike, L. T.; de Zubicaray, G. I.; McMahon, K. L.; Wright, M. J.; Medland, S. E.; Blangero, J. E.; Glahn, D. C.; Kochunov, P.; Haberg, A. K.; Thompson, P. M.; Jahanshad, N.
10.1101/2024.02.22.581646 — neuroscience — Posted on 2024-02-27
540 Neuronal and behavioral responses to naturalistic texture images in macaque monkeys
Ziemba, C. M.; Goris, R. L. T.; Stine, G. M.; Perez, R. K.; Simoncelli, E. P.; Movshon, J. A.
10.1101/2024.02.22.581645 — neuroscience — Posted on 2024-02-27
542 A patient-derived amyotrophic lateral sclerosis blood-brain barrier cell model reveals focused ultrasound-mediated anti-TDP-43 antibody delivery.
Wasielewska, J. M.; Castro Cabral-da-Silva, M.; Pecoraro, M.; Nguyen, T. H.; La Bella, V.; Oikari, L. E.; Ooi, L.; White, A. R.
10.1101/2024.02.22.581567 — neuroscience — Posted on 2024-02-27
543 Optogenetic fMRI reveals therapeutic circuits of subthalamic nucleus deep brain stimulation
Li, Y.; Lee, S.; Yu, C.; Hsu, L.-M.; Wang, T.-W. W.; Do, K.; Kim, H.-J.; Shih, Y.-Y. I.; Grill, W. M.
10.1101/2024.02.22.581627 — neuroscience — Posted on 2024-02-27
544 MRI mapping of hemodynamics in the human spinal cord
Hemmerling, K. J.; Hoggarth, M. A.; Sandhu, M. S.; Parrish, T. B.; Bright, M. G.
10.1101/2024.02.22.581606 — physiology — Posted on 2024-02-27
548 finsyncR, an R package to synchronize 27 years of fish and invertebrate data across the United States
Mahon, M. B.; Jones, D. K.; Hill, R. A.; Brown, T. N.; Brown, E. A.; Kunz, S.; Rumschlag, S. L.
10.1101/2024.02.22.581615 — ecology — Posted on 2024-02-27
549 Single-neuron spiking variability in hippocampus dynamically tracks sensory content during memory formation in humans
Waschke, L.; Kamp, F.; van den Elzen, E.; Krishna, S.; Lindenberger, U.; Rutishauser, U.; Garrett, D. D.
10.1101/2023.02.23.529684 — neuroscience — Posted on 2024-02-27
551 Resilience and vulnerability of speech neural tracking to early auditory deprivation
Federici, A.; Fantoni, M.; Pavani, F.; Handjaras, G.; Bednaya, E.; Martinelli, A.; Berto, M.; Ricciardi, E.; Nava, E.; Orzan, E.; Bianchi, B.; Bottari, D.
10.1101/2024.02.22.581545 — neuroscience — Posted on 2024-02-27
552 SMAC mimetics overcome apoptotic resistance in ovarian cancer through MSLN-TNF alpha axis
Coelho, R.; Seashore-Ludlow, B.; Schutz, S.; Christopher Lombardo, F.; Moussaud-Lamodiere, E.; Casanova, R.; Ficek-Pascual, J.; Brunhilde Labrosse, K.; Hensle, M.; Lopez-Nunez, M.; Rimmer, N.; Fedier, A.; Lima, R.; Montavon Sartorius, C.; Kurzeder, C.; Singer, F.; Bertolini, A.; The TumorProfiler Consortium, ; Fucikova, J.; Ratsch, G.; Bodenmiller, B.; Kallioniemi, O.; Ostling, P.; David, L.; Heinzelmann-Schwarz, V.; Jacob, F.
10.1101/2024.01.24.576987 — cancer biology — Posted on 2024-02-27
553 Decoupling of the Onset of Anharmonicity between a Protein and Its Surface Water around 200 K
Zheng, L.; Zhou, B.; Wu, B.; Huang, J.; Tyagi, M.; Sakai, V. G.; Yamada, T.; O'Neill, H.; Zhang, Q.; Hong, L.
10.1101/2023.10.18.562890 — biophysics — Posted on 2024-02-27
556 Temporal dynamics of short-term neural adaptation across human visual cortex
Brands, A. M.; Devore, S.; Devinsky, O.; Doyle, W.; Flinker, A.; Friedman, D.; Dugan, P.; Winawer, J.; Groen, I. I. A.
10.1101/2023.09.13.557378 — neuroscience — Posted on 2024-02-27
560 Overexpressing NRT2.7 induces nitrate export from the vacuole and increases growth of Arabidopsis
Armengaud, P.; De Angeli, A.; Berquin, P.; Brehaut, V.; Durand, M.; Daniel-Vedele, F.; Krapp, A.; Filleur, S.
10.1101/2024.02.26.582130 — plant biology — Posted on 2024-02-27
562 GhCPK28 negatively regulates the immune response by phosphorylating GhTIFY3b
Gao, S.; Shao, W.; Wu, J.; Zhao, Z.; Hu, W.; Shao, P.; Hua, J.; Zou, B.; Huang, Q.
10.1101/2024.02.23.581816 — plant biology — Posted on 2024-02-27
563 Functional marker CAPS-799 of the TaPHT1;9-4B gene is useful for screening phosphorus-efficient wheat cultivars
Guozhang, K.; Jinfeng, W.; Zedong, C.; Huanting, S.; Chuang, L.; Kaixia, F.; Bo, Y.; Tiancai, G.; Yonghua, W.; Pengfei, W.
10.1101/2024.02.23.581827 — plant biology — Posted on 2024-02-27
564 Photoreceptor-induced sinapate synthesis contributes to photoprotection in Arabidopsis
Leonardelli, M.; Tissot, N.; Podolec, R.; Ares-Orpel, F.; Glauser, G.; Ulm, R.; Demarsy, E.
10.1101/2024.02.26.582123 — plant biology — Posted on 2024-02-27
567 SHOOTMERISTEMLESS autoactivation: A prerequisite for fruit metamorphosis
Dong, Y.; Hu, Z.-C.; Majda, M.; Sun, H.-R.; Zhang, Y.; Ding, Y.-N.; Yuan, Q.; Su, T.-B.; Lv, T.-F.; Gao, F.; Xu, G.; Smith, R. S.; Ostergaard, L.
10.1101/2024.02.23.581830 — plant biology — Posted on 2024-02-27
569 A missense mutation in the gene encoding the Mg-chelatase subunit I leads to a viable pale green line with phenotypic features of potential interest for barley breeding programs
Persello, A.; Tadini, L.; Rotasperti, L.; Ballabio, F.; Tagliani, A.; Torricella, V.; Jahns, P.; Dalal, A.; Moshelion, M.; Camilloni, C.; Rosignoli, S.; Hansson, M.; Cattivelli, L.; Horner, D. S.; Rossini, L.; Tondelli, A.; Salvi, S.; Pesaresi, P.
10.1101/2024.02.24.581867 — plant biology — Posted on 2024-02-27
570 Remodelling of Skeletal Muscle Myosin Metabolic States in Hibernating Mammals
Lewis, C. T. A.; Melhedegaard, E. G.; Ognjanovic, M. M.; Olsen, M. S.; Laitila, J.; Seaborne, R. A. E.; Gronset, M. N.; Zhang, C.; Iwamoto, H.; Hessel, A. L.; Kuehn, M. N.; Merino, C.; Amigo, N.; Frobert, O.; Giroud, S.; Staples, J. F.; Goropashnaya, A. V.; Fedorov, V. B.; Barnes, B. M.; Toien, O.; Drew, K. L.; Sprenger, R. J.; Ochala, J.
10.1101/2023.11.14.566992 — physiology — Posted on 2024-02-27
574 Altered hepatic metabolism mediates sepsis preventive effects of reduced glucose supply in infected preterm newborns
Baek, O.; Muk, T.; Wu, Z.; Ye, Y.; Khakimov, B.; Casano, A. M.; Gangadharan, B.; Bilic, I.; Brunse, A.; Sangild, P. T.; Nguyen, D. N.
10.1101/2023.09.11.557116 — immunology — Posted on 2024-02-27
575 Prioritizing Metabolic Gene Regulators through Multi-Omic Network Integration in Maize
Gomez-Cano, F. A.; Rodriguez, J.; Zhou, P.; Chu, Y.-H.; Magnusson, E.; Gomez-Cano, L.; Krishnan, A.; Springer, N. M.; de Leon, N.; Grotewold, E.
10.1101/2024.02.26.582075 — plant biology — Posted on 2024-02-27
577 NSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesis
Parolia, A.; Eyunni, S.; Verma, B. K.; Young, E.; Liu, L.; George, J.; Aras, S.; Das, C. K.; Mannan, R.; ur Rasool, R.; Luo, J.; Carson, S. E.; Mitchell-Velasquez, E.; Liu, Y.; Xiao, L.; Gajjala, P. R.; Jaber, M.; He, T.; Qiao, Y.; Pang, M.; Zhang, Y.; Alhusayan, M.; Cao, X.; Tavana, O.; Hou, C.; Wang, Z.; Ding, K.; Chinnaiyan, A. M.; Asangani, I. A.
10.1101/2024.02.22.581560 — cancer biology — Posted on 2024-02-27
578 Canonical AREs are tumor suppressive regulatory elements in the prostate
Augello, M. A.; Chen, X.; Liu, D.; Lin, K.; Hakansson, A.; Sjostrom, M.; Khani, F.; Deonarine, L. D.; Liu, Y.; Travascio-Green, J.; Wu, J.; Loda, M.; Feng, F. Y.; Robinson, B. D.; Davicioni, E.; Sboner, A.; Barbieri, C.
10.1101/2024.02.23.581466 — cancer biology — Posted on 2024-02-27
579 High-confidence calling of normal epithelial cells allows identification of a novel stem-like cell state in the colorectal cancer microenvironment
Wei, T.-T.; Blanc, E.; Peidli, S.; Bischoff, P.; Trinks, A.; Horst, D.; Sers, C.; Bluthgen, N.; Beule, D.; Morkel, M.; Obermayer, B.
10.1101/2024.02.23.581690 — cancer biology — Posted on 2024-02-27
580 Synergistic and antagonistic drug-drug interactions are prevalent but not conserved across acute myeloid leukemia cell lines
Kalkan, F. N.; Yildiz, M. S.; Temamogullari Wood, E.; Farid, M.; McCoy, M.; Zhang, C. C.; Posner, B.; Chung, S. S.; Toprak, E.
10.1101/2024.02.23.581821 — cancer biology — Posted on 2024-02-27
581 Induction of expansion of ex vivo NK cells using a new feeder cell built in Brazil. An extended flow cytometry evaluation of K562.mbIL21.4BBL
Watanabe, C. M.; Ishihama Suzuki, C.; Marins dos Santos, A.; Aloia, T. P. A.; Lee, G.; Wald, D.; Okamoto, O. K.; Azevedo, J. T. C. d.; Godoy, J. A. P. d.; Santos, F. P. S.; Weinlich, R.; Kerbauy, L. N.; Kutner, J. M.; Paiva, R. d. M. A.; Hamerschlak, N.
10.1101/2024.02.23.581719 — cancer biology — Posted on 2024-02-27
582 NINJ1 regulates ferroptosis via xCT antiporter interaction and CoA modulation
Chen, S.-Y.; Lin, C.-C.; Wu, J.; Chen, Y.; Wang, Y.-E.; Setayeshpour, Y.; Mestre, A.; Chi, J.-T. A.
10.1101/2024.02.22.581432 — cancer biology — Posted on 2024-02-27
587 Short-term memory, attentional control and brain size in primates
van Schaik, C.; Jacobs, I.; Burkart, J. M.; Sauciuc, G.-A.; Schuppli, C.; Persson, T.; Song, Z.
10.1101/2024.02.26.582100 — animal behavior and cognition — Posted on 2024-02-27
589 Temporal Analysis of Pituitary Transcriptional Dynamics in Mice Models of Hypopituitarism During Postnatal Development
Marques, J. M.; Chang, C. v.; Trigueiro, N. S.; Araujo, R. V.; Cirqueira, C. S.; Russo, L. C.; Viscardi, B. A.; Mendonca, B.; Hoch, N. C.; Carvalho, L. R.
10.1101/2024.02.26.582133 — developmental biology — Posted on 2024-02-27
590 Transcriptomic analysis of the human habenula in schizophrenia
Yalcinbas, E. A.; Ajanaku, B.; Nelson, E. D.; Garcia-Flores, R.; Montgomery, K. D.; Stolz, J. M.; Wu, J.; Divecha, H. R.; Chandra, A.; Bharadwaj, R. A.; Bach, S.; Rajpurohit, A.; Tao, R.; Shin, J.-H.; Kleinman, J. E.; Hyde, T. M.; Weinberger, D. R.; Huuki-Myers, L. A.; Collado-Torres, L.; Maynard, K. R.
10.1101/2024.02.26.582081 — neuroscience — Posted on 2024-02-27
594 Genetic similarity between relatives provides evidence on the presence and history of assortative mating
Sunde, H. F.; Eftedal, N. H.; Cheesman, R.; Corfield, E. C.; Kleppesto, T. H.; Seierstad, A. C.; Ystrom, E.; Eilertsen, E. M.; Torvik, F. A.
10.1101/2023.06.27.546663 — genetics — Posted on 2024-02-27
597 Distinct streams for supervised and unsupervised learning in the visual cortex
Zhong, L.; Baptista, S.; Gattoni, R.; Arnold, J.; Flickinger, D.; Stringer, C.; Pachitariu, M.
10.1101/2024.02.25.581990 — neuroscience — Posted on 2024-02-27
599 Peripheral Neuronal Activation Shapes the Microbiome and Alters Gut Physiology
Griffiths, J. A.; Yoo, B. B.; Thuy-Boun, P.; Cantu, V.; Weldon, K.; Challis, C.; Sweredoski, M. J.; Chan, K. Y.; Thron, T. M.; Sharon, G.; Moradian, A.; Humphrey, G.; Zhu, Q.; Shaffer, J.; Wolan, D. W.; Dorrestein, P.; Knight, R.; Gradinaru, V.; Mazmanian, S.
10.1101/2021.04.12.439539 — physiology — Posted on 2024-02-27
600 A multiprotein signaling complex sustains AKT and mTOR/S6K activity necessary for the survival of cancer cells undergoing stress
Teran, O. Y.; Zanotelli, M. R.; Lin, M.-c. J.; Schmitt, R. R.; Green, K. S.; Rojas, K. S.; Hwang, I. Y.; Cerione, R. A.; Wilson, K. F.
10.1101/2023.01.03.522657 — cancer biology — Posted on 2024-02-27
601 Dysregulation of the p53 pathway provides a therapeutic target in aggressive pediatric sarcomas with stem-like traits
Curylova, L.; Staniczkova Zambo, I.; Neradil, J.; Kyr, M.; Jurackova, N.; Pavlova, S.; Polaskova, K.; Mudry, P.; Sterba, J.; Veselska, R.; Skoda, J.
10.1101/2024.01.17.576012 — cancer biology — Posted on 2024-02-27
603 β-amino acids reduce ternary complex stability and alter the translation elongation mechanism
Cruz Navarrete, F. A.; Griffin, W. C.; Chan, Y.-C.; Martin, M. I.; Alejo, J. L.; Natchiar, S. K.; Knudson, I.; Altman, R. B.; Schepartz, A.; Miller, S. J.; Blanchard, S. C.
10.1101/2024.02.24.581891 — biochemistry — Posted on 2024-02-27
604 Intramolecular feedback regulation of the LRRK2 Roc G domain by a LRRK2 kinase dependent mechanism
Gilsbach, B. K.; Ho, F. Y.; Riebenbauer, B.; Zhang, X.; Guaitoli, G.; Kortholt, A.; Gloeckner, C. J.
10.1101/2023.07.31.549909 — biochemistry — Posted on 2024-02-27
607 ROCK and the actomyosin network control biomineral growth and morphology during sea urchin skeletogenesis
Hijaze, E.; Gildor, T.; Seidel, R.; Layous, M.; Winter, M.; Bertinetti, L.; Politi, Y.; de-Leon, S. B.-T.
10.1101/2022.12.21.521381 — developmental biology — Posted on 2024-02-27
608 Haploidy-linked cell proliferation defects limit larval growth in Zebrafish
Yaguchi, K.; Saito, D.; Menon, T.; Matsura, A.; Mizutani, T.; Kotani, T.; Nair, S.; Uehara, R.
10.1101/2022.05.12.491746 — developmental biology — Posted on 2024-02-27
609 Mechanotransductive feedback control of endothelial cell motility and vascular morphogenesis
Mason, D. E.; Camacho, P.; Goeckel, M.; Tobin, B. R.; Vega, S. L.; Wu, P.-H.; Johnson, D.; Heo, S.-J.; Wirtz, D.; Burdick, J. A.; Wood, L.; Chow, B. Y.; Stratman, A. N.; Boerckel, J. D.
10.1101/2022.06.15.496293 — cell biology — Posted on 2024-02-27
611 Nuclear GAPDH cascade mediates pathological cardiac hypertrophy
Zhang, M.; Kariya, T.; Numata, G.; Sasaki, H.; Sasaki, M.; Ramos, A.; Nakamura, S.; Iwakiri, M.; Koitabashi, N.; Zhu, G.; Tsujimura, T.; Lee, D.-i.; Tristan, C.; Shahani, N.; Tsuchiya, Y.; Jaaro-Peled, H.; Sasano, T.; Slusher, B. S.; Kass, D.; Saitoh, T.; Ishizuka, K.; Sawa, A.; Takimoto, E.
10.1101/844902 — molecular biology — Posted on 2024-02-27
613 HIV-1 Vpr combats the PU.1-driven antiviral response in primary human macrophages.
Virgilio, M. C.; Ramnani, B.; Chen, T.; Disbennett, W. M.; Lubow, J.; Welch, J. D.; Collins, K. L.
10.1101/2023.03.21.533528 — microbiology — Posted on 2024-02-27
614 Inhibitors of the Small Membrane (M) Protein Viroporin Prevent Zika Virus Infection
Brown, E.; Swinscoe, G.; Lefteri, D.; Singh, R.; Moran, A.; Thompson, R.; Maskell, D.; Beaumont, H.; Bentham, M. J.; Donald, C.; Kohl, A.; Macdonald, A.; Ranson, N.; Foster, R.; McKimmie, C. S.; Kalli, A. C.; Griffin, S. C.
10.1101/2021.03.11.435022 — microbiology — Posted on 2024-02-27
615 HippoMaps: Multiscale cartography of the human hippocampal formation
DeKraker, J.; Cabalo, D. G.; Royer, J.; Khan, A. R.; Karat, B.; Benkarim, O.; Rodriguez-Cruces, R.; Frauscher, B.; Pana, R.; Hansen, J. Y.; Misic, B.; Valk, S. L.; Lau, J. C.; Kirschner, M.; Bernasconi, A.; Bernasconi, N.; Muenzing, S.; Axer, M.; Amunts, K.; Evans, A. C.; Bernhardt, B. C.
10.1101/2024.02.23.581734 — neuroscience — Posted on 2024-02-27
616 Electrophysiological signatures of veridical head direction in humans
Griffiths, B. J.; Schreiner, T.; Schaefer, J. K.; Vollmar, C.; Kaufmann, E.; Quach, S.; Remi, J.; Noachtar, S.; Staudigl, T.
10.1101/2023.01.26.525724 — neuroscience — Posted on 2024-02-27
617 Multimodal gradients of human basal forebrain connectivity
Chakraborty, S.; Haast, R. A.; Onuska, K. M.; Kanel, P.; Khan, A. R.; Schmitz, T. W.
10.1101/2023.05.26.541324 — neuroscience — Posted on 2024-02-27
619 Flexible communication between cell assemblies and 'reader' neurons
Pompili, M. N.; Todorova, R.; Boucly, C. J.; Leroux, E. M.; Wiener, S.; Zugaro, M.
10.1101/2022.09.06.506754 — neuroscience — Posted on 2024-02-27
620 How motivational interviewing shifts food choices and craving-related brain responses to healthier options
Rodrigues, B.; Khalid, I.; Frileux, S.; Flament, B.; Yoldas, Z.; Rampanana, M.; Aubertin, H.; Oppert, J.-M.; Poitou, C.; Rotge, J.-Y.; Fossati, P.; Koban, L.; Schmidt, L.
10.1101/2023.10.13.562241 — neuroscience — Posted on 2024-02-27
622 Nationwide Inclusive Facilitator Training: Mindsets, Practices and Growth
Codding, D.; Yen, A. H.; Lewis, H.; Johnson-Ojeda, V.; Frey, R. F.; Hokanson, S. C.; Goldberg, B. B.
10.1101/2024.01.08.574770 — scientific communication and education — Posted on 2024-02-27
623 Reduced mitochondrial transcription sensitizes acute myeloid leukemia cells to BCL-2 inhibition
Arabanian, L. S.; Adamsson, J.; Unger, A.; Di Lucrezia, R.; Bergbrede, T.; Ashouri, A.; Larsson, E.; Nussbaumer, P.; Klebl, B. M.; Palmqvist, L.; Gustafsson, C. M.
10.1101/2022.09.23.509145 — cancer biology — Posted on 2024-02-27
625 Cytometry Masked Autoencoder: An Accurate and Interpretable Automated Immunophenotyper
Kim, J.; Ionita, M.; Lee, M.; McKeague, M. L.; Pattekar, A.; Painter, M. M.; Wagenaar, J.; Truong, V.; Norton, D. T.; Mathew, D.; Nam, Y.; Apostolidis, S. A.; Clendenin, C.; Orzechowski, P.; Jung, S.-H.; Woerner, J.; Ittner, C. A. G.; Turner, A. P.; Esperanza, M.; Dunn, T. G.; Mangalmurti, N. S.; Reilly, J. P.; Meyer, N. J.; Calfee, C. S.; Liu, K. D.; Matthy, M. A.; Swigart, L. B.; Burnham, E. L.; McKeehan, J.; Gandotra, S.; Russel, D. W.; Gibbs, K. W.; Thomas, K. W.; Barot, H.; Greenplate, A. R.; Wherry, E. J.; Kim, D.
10.1101/2024.02.13.580114 — bioinformatics — Posted on 2024-02-27
627 Challenging the Astral mass analyzer - up to 5300 proteins per single-cell at unseen quantitative accuracy to study cellular heterogeneity.
Bubis, J. A.; Arrey, T. N.; Damoc, E.; Delanghe, B.; Slovakova, J.; Sommer, T. M.; Kagawa, H.; Pichler, P.; Rivron, N. C.; Mechtler, K.; Matzinger, M.
10.1101/2024.02.01.578358 — biochemistry — Posted on 2024-02-27
628 Structural proteomics of a bacterial mega membrane protein complex: FtsH-HflK-HflC
Akkulak, H.; Ince, H. K.; Goc, G.; Lebrilla, C. B.; Kabasakal, B. V.; Ozcan, S.
10.1101/2023.06.07.544024 — biochemistry — Posted on 2024-02-27
635 Ivermectin resistance in dung beetles exposed for multiple generations
Tokman, D. G.; Torres, A. A.; Baena-Diaz, F.; Bustos, C.; Martinez M, I.
10.1101/2023.05.08.539900 — ecology — Posted on 2024-02-27
642 Deep plasma proteomics with data-independent acquisition: A fastlane towards biomarkers identification.
Ward, B.; Pyr dit Ruys, S.; Balligand, J.-L.; Belkhir, L.; Cani, P. D.; Collet, J.-F.; De Greef, J.; Gatto, L.; Haufroid, V.; Jodogne, S.; Kabamba, B.; Lingurski, M.; Yombi, J. C.; Vertommen, D.; Elens, L.
10.1101/2024.02.23.581160 — systems biology — Posted on 2024-02-26
649 Unraveling the Complexity of Abdominal Aortic Aneurysm: Multiplexed Imaging Insights into C-Reactive Protein-Related Variations
Kim, E. N.; Seok, H. Y.; Koh, J.; Yang, W.; Lee, G. H.; Choi, W. H.; Lim, J. S.; Ok, Y. J.; Choi, J.-S.; Kim, C. J.; Zhuang, L.; Chang, Y. H.; Oh, S. J.
10.1101/2024.02.22.581315 — pathology — Posted on 2024-02-26
652 Loss of the APP regulator RHBDL4 preserves memory in an Alzheimer's disease mouse model.
Penalva, Y. C. M.; Paschkowsky, S.; Yang, J.; Recinto, S. J.; Cinkorpumin, J.; Xiao, B.; Nitu, A.; Munter, H. M.; Michalski, B.; Fahnestock, M.; Pastor, W. A.; Bennett, D. A.; Munter, L. M.
10.1101/2024.02.22.579698 — animal behavior and cognition — Posted on 2024-02-26
653 Evaluation of Bayesian Linear Regression Models for Gene Set Prioritization in Complex Diseases
Gholipourshahraki, T.; Bai, Z.; Shrestha, M.; Hjelholt, A. J.; Kjolby, M.; Rohde, P. D.; Sorensen, P.
10.1101/2024.02.23.581718 — genomics — Posted on 2024-02-26
659 Zebrafish and cellular models of SELENON-Related Myopathy exhibit novel embryonic and metabolic phenotypes
Barraza-Flores, P.; Moaghadaszadeh, B. S.; Lee, W.; Issac, B.; Sung, L.; Hickey, E.; Rockowitz, S.; Sliz, P.; Beggs, A. H.
10.1101/2024.02.26.581979 — molecular biology — Posted on 2024-02-26
662 The Chlamydia trachomatis Inc Tri1 interacts with TRAF7 to displace native TRAF7 interacting partners
Herrera, C.; McMahon, E.; Swaney, D. L.; Sherry, J.; Pha, K.; Adams-Boone, K.; Johnson, J.; Krogan, N.; Stevers, M.; Solomon, D.; Elwell, C.; Engel, J.
10.1101/2024.02.26.581999 — microbiology — Posted on 2024-02-26
665 MetaWorm: A Complete Model Bridging Brain, Body and Environment of C. elegans
Zhao, M.; Wang, N.; Jiang, X.; Ma, X.; Ma, H.; He, G.; Du, K.; Ma, L.; Huang, T.
10.1101/2024.02.22.581686 — neuroscience — Posted on 2024-02-26
666 Development of rat organoids to study intestinal adaptations after Roux-en-Y Gastric Bypass
Benhaddou, S.; Ribeiro-Parenti, L.; Vaugrente, A.; Willemetz, A.; Gaudichon, C.; Douard, V.; Le Gall, M.; Larraufie, P.
10.1101/2024.02.24.581868 — physiology — Posted on 2024-02-26
668 Exploring the conformational space of protein-protein complex with transformer-based generative model
Wang, J.; Wang, X.; Chu, Y.; Li, C.; Li, X.; Meng, X.; Fang, Y.; No, K. T.; Mao, J.; Zeng, X.
10.1101/2024.02.24.581708 — bioinformatics — Posted on 2024-02-26
671 Code for Collagen Folding Deciphered
Malcor, J.-D.; Ferruz, N.; Romero-Romero, S.; Dhingra, S.; Sagar, V.; Jalan, A. A.
10.1101/2024.02.24.581883 — biochemistry — Posted on 2024-02-26
672 A Fluorogenic Green Merocyanine-Based Probe to Detect Heparanase-1 Activity
Rabinowitz, Z. M.; Wang, Z.; Liu, J.; Zhang, Y.; Jimenez Ybargollin, A.; Saketkhou, M.; Cui, L.
10.1101/2024.02.25.581963 — biochemistry — Posted on 2024-02-26
677 Global variation in the ratio of sapwood to leaf area explained by optimality principles
Xu, H.; Wang, H.; Prentice, I. C.; Harrison, S.; Rowland, L.; Mencuccini, M.; Sanchez-Martinez, P.; He, P.; Wright, I. J.; Sitch, S.; Ye, Q.
10.1101/2024.02.24.581904 — ecology — Posted on 2024-02-26
681 Decoupled degradation and translation enables noise-modulation by poly(A)-tails
Grandi, C.; Emmaneel, M.; Nelissen, F. H. T.; Roosenboom, L. W. M.; Petrova, Y.; Elzokla, O.; Hansen, M. M. K.
10.1101/2024.02.26.582038 — molecular biology — Posted on 2024-02-26
682 High performance TadA-8e derived cytosine and dual base editors with undetectable off-target effects in plants
Fan, T.; Cheng, Y.; Wu, Y.; Liu, S.; Tang, X.; He, Y.; Liao, S.; Zheng, X.; Zhang, T.; Qi, Y.; Zhang, Y.
10.1101/2024.02.25.581917 — molecular biology — Posted on 2024-02-26
686 The energy metabolism of Cupriavidus necator in different trophic conditions
Jahn, M.; Crang, N.; Gynna, A. H.; Kabova, D.; Frielingsdorf, S.; Lenz, O.; Charpentier, E.; Hudson, E. P.
10.1101/2024.02.26.582058 — microbiology — Posted on 2024-02-26
688 Natural products from food sources can alter the spread of AMR plasmids in Enterobacterales
Alav, I.; Pordelkhaki, P.; Rodriguez Navarro, J.; Neo, O.; Kessler, C.; Awodipe, R. J.; Cliffe, P.; Marton, H.; Gibbons, S.; Buckner, M. M. C.
10.1101/2024.02.26.582065 — microbiology — Posted on 2024-02-26
690 Heterologous Prime-Boost with Immunologically Orthogonal Protein Nanoparticles for Peptide Immunofocusing
Bhattacharya, S.; Jenkins, M. C.; Keshavarz-Joud, P.; Bourque, A. R.; White, K.; Barkane, A. M. A.; Bryksin, A. V.; Hernandez, C.; Kopylov, M.; Finn, M. G.
10.1101/2024.02.24.581861 — immunology — Posted on 2024-02-26
691 Modeling gene-environment interactions in Parkinson's Disease: Helicobacter pylori infection of Pink1-/- mice induces CD8 T cell-dependent motor and cognitive dysfunction.
Kazanova, A.; Sung, J.; Oliveira, N. L.; Gavino, C.; Bessaiah, H.; Pei, J.; Burns, L.; Miller, W.; Brouillard-Galipeau, M.; Zhu, L.; Guerra, L. M.; Elemeery, M. N.; Recinto, S. J.; MacDonald, A.; Lanoix, J.; Thibault, P.; McBride, H. M.; Desjardins, M.; Stratton, J. A.; Labrecque, N.; Gruenheid, S.
10.1101/2024.02.25.580545 — immunology — Posted on 2024-02-26
692 Odor-induced persistent neural activity in associativeencoding in humans
Tarrida, J.; Fuentemilla, L.; Marco-Pallares, J.; Moreno, M.; Panyella, D.; Vidal, J.
10.1101/2024.02.23.581728 — neuroscience — Posted on 2024-02-26
693 Developmentally stable representations of naturalistic image structure in macaque visual cortex
Lee, G. M.; Rodriguez Deliz, C. L.; Bushnell, B. N.; Majaj, N. J.; Movshon, J. A.; Kiorpes, L.
10.1101/2024.02.24.581889 — neuroscience — Posted on 2024-02-26
695 The physiology of bud dormancy and cell cycle status in grapevine
Hermawaty, D.; Clode, P.; Considine, J. A.; Signorelli, S.; Considine, M. J.
10.1101/2024.02.22.581692 — plant biology — Posted on 2024-02-26
696 Biochemical characterization of naturally occurring mutations in SARS-CoV-2 RNA-dependent RNA polymerase
Danda, M.; Klimesova, A.; Kuskova, K.; Dostalkova, A.; Pagacova, A.; Prchal, J.; Kapisheva, M.; Ruml, T.; Rumlova, M.
10.1101/2024.02.24.581855 — biochemistry — Posted on 2024-02-26
698 Friction-induced budding of a cancer cell monolayer
Dedenon, M.; Barbazan, J.; Perez Gonzalez, C.; Vignjevic, D.; Sens, P.
10.1101/2024.02.26.582028 — biophysics — Posted on 2024-02-26
699 Machine learning identifies cell-free DNA 5-hydroxymethylation biomarkers that detect occult colorectal cancer in PLCO Screening Trial subjects
West-Szymanski, D. C.; Zhang, Z.; Cui, X.-L.; Kowitwanich, K.; Gao, L.; Deng, Z.; Dougherty, U.; Williams, C.; Merkle, S.; Moore, M.; He, C.; Bissonnette, M.; Zhang, W.
10.1101/2024.02.25.581955 — genomics — Posted on 2024-02-26
700 TASOR expression in naive embryonic stem cells safeguards their developmental potential
Pinzon-Arteaga, C. A.; O'Hara, R.; Mazzagati, A.; Ballard, E.; Hu, Y.; Pan, A.; Schmitz, D. A.; Wei, Y.; Sakurai, M.; Ly, P.; Banaszynski, L.; Wu, J.
10.1101/2024.02.25.581951 — developmental biology — Posted on 2024-02-26
703 Mechanical confinement induces ferroptosis through mitochondrial dysfunction
Zhou, F.; Kang, C.; Li, J.; Yang, A.; Ju, R. J.; Sun, Y.; Liang, L.; Hu, X.; Stehbens, S. J.; Wu, C.
10.1101/2024.02.23.581510 — cell biology — Posted on 2024-02-26
704 PTEN and the PTEN-like phosphatase CnrN have both distinct and overlapping roles in a Dictyostelium chemorepulsion pathway
Consalvo, K. M.; Rijal, R.; Beruvides, S.; Mitchell, R.; Beauchemin, K.; Collins, D.; Scoggin, J.; Scott, J.; Gomer, R.
10.1101/2024.02.23.581751 — cell biology — Posted on 2024-02-26
705 Sleep pressure accumulates in a voltage-gated lipid peroxidation memory
Rorsman, H. O.; Müller, M. A.; Liu, P. Z.; Sanchez, L. G.; Kempf, A.; Gerbig, S.; Spengler, B.; Miesenboeck, G.
10.1101/2024.02.25.581768 — neuroscience — Posted on 2024-02-26
706 Resolvin D2/GPR18 signaling enhances monocytic myeloid-derived suppressor cell function to mitigate abdominal aortic aneurysm formation
Bellotti, P.; Ladd, Z.; Leroy, V.; Su, G.; Sharma, S.; Hartman, J.; Krebs, J.; Viscardi, C.; Maile, R.; Moldawer, L.; Efron, P. A.; Sharma, A. K.; Upchurch, G. R.
10.1101/2024.02.23.581672 — immunology — Posted on 2024-02-26
707 KSR1 regulates small-cell lung carcinoma tumor initiation and therapy resistance
Chatterjee, D.; Svoboda, R. A.; Huisman, D. H.; Vieira, H. M.; Rao, C.; Askew, J. W.; Fisher, K. W.; Lewis, R. E.
10.1101/2024.02.23.581815 — cancer biology — Posted on 2024-02-26
709 The importance of stereochemistry in the disorder-order continuum of protein-protein interactions
Newcombe, E. A.; Due, A. D.; Sottini, A.; Fernandes, C. B.; Staby, L.; Delaforge, E.; Bartling, C. R. O.; Brakti, I.; Bugge, K.; Schuler, B.; Skriver, K.; Olsen, J. G.; Kragelund, B. B.
10.1101/2024.02.23.581681 — biophysics — Posted on 2024-02-26
712 Revolutionizing GPCR-Ligand Predictions: DeepGPCR with experimental Validation for High-Precision Drug Discovery
Zhang, H.; Fan, H.; Wang, J.; Hou, T.; Saravanan, K. M.; Xia, W.; Kan, H. W.; Li, J.; Zhang, J. Z. H.; xinmiao, L.; Chen, Y.
10.1101/2024.02.25.581988 — bioinformatics — Posted on 2024-02-26
714 WITHDRAWN: Oligomerization of the antimalarial drug target PfATP4 is essential for parasite survival
Ramanathan, A. A.; Morrisey, J. M.; Daly, T. M.; Bergman, L. W.; Mather, M. W.; Vaidya, A. B.
10.1101/2019.12.12.874826 — biochemistry — Posted on 2024-02-26
716 Structural analysis and conformational dynamics of a holo-adhesion GPCR reveal interplay between extracellular and transmembrane domains
Kordon, S. P.; Cechova, K.; Bandekar, S. J.; Leon, K.; Dutka, P.; Siffer, G.; Kossiakoff, A. A.; Vafabakhsh, R.; Arac, D.
10.1101/2024.02.25.581807 — biochemistry — Posted on 2024-02-26
719 Mitotic Block and Epigenetic Repression Underlie Neurodevelopmental Defects and Neurobehavioral Deficits in Congenital Heart Disease
Gabriel, G. C.; Yagi, H.; Tan, T.; Bais, A. S.; Glennon, B.; Stapleton, M. C.; Huang, L.; Reynolds, W. T.; Shaffer, M. G.; Ganapathiraju, M.; Simon, D.; Panigrahy, A.; Wu, Y. L.; Lo, C. W.
10.1101/2023.11.05.565716 — developmental biology — Posted on 2024-02-26
723 Molecular density-accelerated binding-site maturation underlies CENP-T-dependent kinetochore assembly
Tarasovetc, E. V.; Sissoko, G. B.; Mukhina, A. S.; Maiorov, A.; Ataullakhanov, F. I.; Cheeseman, I. M.; Grishchuk, E. L.
10.1101/2024.02.25.581584 — biophysics — Posted on 2024-02-26
724 Enhancement of colorectal cancer therapy through interruption of the HSF1-HSP90 axis by p53 activation or cell cycle inhibition
Isermann, T.; Schneider, K. L.; Wegwitz, F.; De Oliveira, T.; Conradi, L.-C.; Volk, V.; Feuerhake, F.; Papke, B.; Stintzing, S.; Mundt, B.; Kuehnel, F.; Moll, U. M.; Schulz-Heddergott, R.
10.1101/2024.02.22.581507 — cancer biology — Posted on 2024-02-26
725 High-throughput screening for Cushing's disease: therapeutic potential of thiostrepton via cell cycle regulation
Hakata, T.; Yamauchi, I.; Kosugi, D.; Sugawa, T.; Fujita, H.; Okamoto, K.; Ueda, Y.; Fujii, T.; Taura, D.; Inagaki, N.
10.1101/2024.02.22.581351 — cell biology — Posted on 2024-02-26
727 Complete chromosome 21 centromere sequences from a Down syndrome family reveal size asymmetry and differences in kinetochore attachment
Mastrorosa, F. K.; Rozanski, A. N.; Harvey, W. T.; Knuth, J.; Garcia, G.; Munson, K. M.; Hoekzema, K.; Logsdon, G. A.; Eichler, E. E.
10.1101/2024.02.25.581464 — genomics — Posted on 2024-02-26
728 The evolution of reduced facilitation in a four-species bacterial community
Piccardi, P.; Ulrich, E.; Garcia-Garcera, M.; Di Martino, R.; Testa, S. E. A.; Mitri, S.
10.1101/2024.02.22.581583 — evolutionary biology — Posted on 2024-02-26
730 Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1
Oh, W.-J.; Kim, N.; Li, Y.; Yu, R.; Kwon, H.-S.; Song, A.; Jun, M.-H.; Jeong, J.-Y.; Lee, J. H.; Lim, H.-H.; Kim, M.-J.; Kim, J.-W.
10.1101/2022.05.03.490499 — developmental biology — Posted on 2024-02-26
731 Oxytocin and shared intentionality drive variation in cooperation in children
McClung, J.; Triki, Z.; Lancheros Pompeyo, M.; Fassier, R.; Emery, Y.; Bangerter, A.; Clement, F.; Bshary, R.
10.1101/2024.02.25.581910 — developmental biology — Posted on 2024-02-26
732 Rebalancing the motor circuit restores movement in a Caenorhabditis elegans model for TDP-43-toxicity
Koopman, M.; Gungordu, L.; Janssen, L.; Seinstra, R. I.; Richmond, J. E. X.; Okerlund, N.; Wardenaar, R.; Islam, P.; Brown, A. E. X.; Jorgensen, E. M.; Nollen, E. A. A.
10.1101/2023.10.24.563563 — cell biology — Posted on 2024-02-26
734 ROS-induced translational regulation--through spatiotemporal differences in codon recognition--is a key driver of brown adipogenesis
Ip, J. Y.; Wijaya, I.; Lee, L. T.; Lim, Y.; Teoh, D. E.-J.; Chan, C. S. C.; Cui, L.; Begley, T. J.; Dedon, P. C.; Guo, H.
10.1101/2023.12.22.572954 — molecular biology — Posted on 2024-02-26
737 Resident Synovial Macrophages in Synovial Fluid: Implications for Immunoregulation in Infectious and Inflammatory Arthritis
Cyndari, K. I.; Scorza, B. M. I.; Zacharias, Z. R.; Strand, L.; Mahachi, K.; Oviedo, J. M.; Gibbs, L.; Pessoa-Pereira, D.; Ausdal, G.; Hendricks, D.; Yahashiri, R.; Elkins, J. M.; Gulbrandsen, T.; Peterson, A. R.; Willey, M. C.; Fairfax, K. C.; Petersen, C. A. A.
10.1101/2023.09.29.560183 — immunology — Posted on 2024-02-26
738 Age-Related Differences in Affective Behaviors in Mice: Possible Role of Prefrontal Cortical-Hippocampal Functional Connectivity and Metabolomic Profiles
Febo, M.; Mahar, R.; Rodriguez, N. A.; Buraima, J.; Pompilus, M.; Pinto, A. M.; Grudny, M. M.; Bruijnzeel, A.; Merritt, M.
10.1101/2023.11.13.566691 — neuroscience — Posted on 2024-02-26
739 A Systematic Review and Meta-analysis on the Transcriptomic Signatures in Alcohol Use Disorder
Friske, M. M.; Torrico, E. C.; Haas, M. J. W.; Borruto, A. M.; Giannone, F.; Hade, A.-C.; Gao, L.; Yu, Y.; Sutherland, G. T.; Hitzemann, R. J.; Philips, M.-A.; Fei, S. S.; Mayfield, R. D.; Sommer, W. H.; Spanagel, R.
10.1101/2022.12.19.521027 — neuroscience — Posted on 2024-02-26
740 Hypoxia disrupts circadian rhythms in astrocytes and causes synapse engulfment defects
Li, L.; Choi, J.; Shin, C. H.; Htun, S.; Mestan, S.; Voss, A.; Shadrach, J. L.; Puno, A.; Nagar, D.; Ramirez, N.; Rojo, D.; Lee, S. H.; Gibson, E. M.; Kaltschmidt, J. A.; Sloan, S. A.; Chung, W.-S.; Pasca, A. M.
10.1101/2024.02.22.581651 — neuroscience — Posted on 2024-02-26
741 Monkeys engage in visual simulation to solve complex problems
Ahuja, A.; Yusif Rodriguez, N.; Ashok, A. K.; Serre, T.; Desrochers, T.; Sheinberg, D.
10.1101/2024.02.21.581495 — neuroscience — Posted on 2024-02-26
742 Light-exercise-induced dopaminergic and noradrenergic stimulation in the dorsal hippocampus: using a rat physiological exercise model
Hiraga, T.; Hata, T.; Soya, S.; Shimoda, R.; Takahashi, K.; Soya, M.; Inoue, K.; Johansen, J. P.; Okamoto, M.; Soya, H.
10.1101/2023.06.19.545490 — neuroscience — Posted on 2024-02-26
747 A converged ubiquitin-proteasome pathway for the degradation of TOC and TOM tail-anchored receptors
Yang, M.; Chen, S.; Lim, S.-L.; Yang, L.; Zhong, J. Y.; Chan, K. C.; Zhao, Z.; Wong, K.-B.; Wang, J.; Lim, B. L.
10.1101/2023.01.07.523072 — plant biology — Posted on 2024-02-26
749 A pan-tissue, pan-disease compendium of human orphan genes
Singh, U.; Haltom, J.; Guarnieri, J.; Li, J.; Seetharam, A.; Beheshti, A.; Aronow, B.; Wurtele, E. S.
10.1101/2024.02.21.581488 — evolutionary biology — Posted on 2024-02-26
751 Neuroimmune changes underscore pain-associated behaviors and disc herniations in SM/J mice
Novais, E. J.; Ottone, O. K.; Brown, E. V.; Madhu, V.; Tran, V. A.; Dighe, A. S.; Solga, M. D.; Manchel, A.; Lepore, A. C.; Risbud, M. V.
10.1101/2024.02.23.581794 — cell biology — Posted on 2024-02-26
752 Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer's disease.
Chartampila, E.; Elayouby, K. S.; Leary, P.; LaFrancois, J. J.; Alcantara-Gonzalez, D.; Jain, S.; Gerencer, K.; Botterill, J. J.; Ginsberg, S. D.; Scharfman, H.
10.1101/2023.05.12.540428 — neuroscience — Posted on 2024-02-26
756 Metabolic reprogramming of hypoxic tumour-associated macrophages through CSF-1R targeting favours treatment efficiency in colorectal cancers
Gharzeddine, K.; Gonzales Pietro, C.; Malier, M.; Hennot, C.; Grespan, R.; Yamaryo, Y.; Botte, C.; Thomas, F.; Laverriere, M. H.; Girard, E.; Roth, G.; MILLET, A.
10.1101/2024.02.22.581558 — immunology — Posted on 2024-02-25
757 Intervertebral disc cells from human back pain subjects exhibit TNFR1-mediated senescence and lack TNFR2-modulated repair capacity
Gansau, J.; Grossi, E.; Rodriguez, L.; Wang, M.; Laudier, D.; Chaudhary, S.; Hecht, A.; Fu, W.; Sebra, R.; Liu, C.; Iatridis, J. C.
10.1101/2024.02.22.581620 — bioengineering — Posted on 2024-02-25
758 Exploring Arylidene-Indolinone Ligands of Autophagy Proteins LC3B and GABARAP
Leveille, A. N.; Brown, H.; Schwarzrock, T.; True, B.; Plasencia, J.; Neudecker, P.; Üffing, A.; Weiergraber, O. H.; Willbold, D.; Kritzer, J.
10.1101/2024.02.25.581879 — biochemistry — Posted on 2024-02-25
759 β-amino acids reduce ternary complex stability and alter the translation elongation mechanism
Cruz Navarrete, F. A.; Griffin, W. C.; Chan, Y.-C.; Martin, M. I.; Alejo, J. L.; Natchiar, S. K.; Knudson, I.; Altman, R. B.; Schepartz, A.; Miller, S. J.; Blanchard, S. C.
10.1101/2024.02.24.581891 — biochemistry — Posted on 2024-02-25
760 Simultaneous circulation and coinfection of Dengue clades and serotypes in Southern Brazil
Bermann, T.; Baethgen, L. F.; Gregianini, T. S.; Godinho, F. M.; Barcellos, R. B.; Ruivo, A. P.; Bauermann, M.; Selayaran, T. M.; Machado, F.; Schroder, J. A.; Mollmann, E. B.; Martiny, F. L.; Lagranha, V. L.; de Oliveira, L. F. V.; da Veiga, A. B. G.; Zolet, A. C. T.; Wallau, G. L.; Salvato, R. S.
10.1101/2024.02.24.581892 — genomics — Posted on 2024-02-25
761 Evaluation of Bayesian Linear Regression Derived Gene Set Test Methods
Bai, Z.; Gholipourshahraki, T.; Shrestha, M.; Hjelholt, A.; Kjolby, M.; Rohde, P. D.; Sorensen, P.
10.1101/2024.02.23.581726 — genomics — Posted on 2024-02-25
763 The Origins of ATP Dependence in Biological Nitrogen Fixation
Harris, D.; Rucker, H.; Garcia, A.; Yang, Z.-Y.; Chang, S.; Feinsilber, H.; Kacar, B.; Seefeldt, L.
10.1101/2024.02.22.581614 — evolutionary biology — Posted on 2024-02-25
764 mTOR controls growth and internal architecture of human breast cancer spheroids
Hoette, K.; Fischer, S.; Schmitz, A.; Koch, M.; Saeifar, S.; Stelzer, E.; Pampaloni, F.
10.1101/2024.02.24.580871 — cell biology — Posted on 2024-02-25
765 Stabilization of Integrator/INTAC by the small but versatile DSS1 protein
Xu, C.; Zhou, Q.-X.; Zheng, H.; Song, A.; Zhao, W.-Y.; Xiong, Y.; Huang, Z.; Xu, Y.; Cheng, J.; Chen, F. X.
10.1101/2024.02.25.581915 — molecular biology — Posted on 2024-02-25
767 Arp2/3 complex-dependent actin regulation protects the survival of tissue-resident mast cells
Kaltenbach, L.; Mihlan, M.; Ulferts, S.; Müsken, M.; Glaser, K. M.; Mittler, G.; Babina, M.; Innocenti, M.; Grosse, R.; Stradal, T. E. B.; Lämmermann, T.
10.1101/2024.02.23.581763 — immunology — Posted on 2024-02-25
769 Heterozygosity for Crohn's Disease Risk Allele of ATG16L1 Protects against Bacterial Infection
Yao, X.; Rudensky, E.; Martin, P. K.; Zwack, E. E.; He, Z.; Furtado, G. C.; Lira, S. A.; Torres, V. J.; Shopsin, B.; Cadwell, K.
10.1101/2024.02.22.581423 — immunology — Posted on 2024-02-25
771 Engineering oncogenic hotspot mutations on SF3B1 via CRISPR-directed PRECIS mutagenesis
Fernandez, M.; Jia, Q.; Yu, L.; Wang, X.; Hart, K.; Jia, Z.; Lin, R.-J.; Wang, L.
10.1101/2024.02.23.581842 — cancer biology — Posted on 2024-02-25
773 Influenza A Viral Burst Size from Thousands of Infected Single Cells Using Droplet Quantitative PCR (dqPCR)
Zath, G. K.; Thomas, M. M.; Loveday, E. K.; Bikos, D. A.; Sanche, S.; Ke, R.; brooke, c.; Chang, C. B.
10.1101/2024.02.23.581786 — bioengineering — Posted on 2024-02-25
775 Boosting the Sensitivity of Quantitative Single-Cell Proteomics with Activated Ion-Tandem Mass Tags (AI-TMT)
Peters-Clarke, T.; Liang, Y.; Mertz, K. L.; Lee, K. W.; Westphall, M. S.; Hinkle, J. D.; McAlister, G. C.; Syka, J. E. P.; Kelly, R. T.; Coon, J.
10.1101/2024.02.24.581874 — biochemistry — Posted on 2024-02-25
776 Characterisation of mesenchymal stromal cells in the skin of Atlantic salmon
Ruiz-Daniels, R.; J Salisbury, S.; Sveen, L.; S Taylor, R.; Vaadal, M.; Tengs, T.; Monaghan, S.; R Villamayor, P.; Ballantyne, M.; Penaloza, C.; D Fast, M.; E Bron, J.; D Houston, R.; Robinson, N.; Robledo, D.
10.1101/2024.02.23.581759 — genomics — Posted on 2024-02-25
778 Extracellular chemosymbiont populations in a shallow-water thyasirid clam potentially shaped by priority effect
Li, M.; Li, Y.; Mao, S.; Liu, X.; Wang, H.; Chen, C.; Liu, X.; Zhuang, G.-C.; Zhang, W.; Sun, J.
10.1101/2024.02.25.581922 — microbiology — Posted on 2024-02-25
779 EmbB and EmbC Regulate the Sensitivity of Mycobacterium abscessus to Echinomycin
He, J.; Gao, Y.; Wang, J.; Hameed, H. M. A.; Wang, S.; Fang, C.; Tian, X.; Zhang, J.; Han, X.; Ju, Y.; Tan, Y.; Ma, J.; Ju, J.; Hu, J.; Liu, J.; Zhang, T.
10.1101/2024.02.25.578291 — microbiology — Posted on 2024-02-25
780 Pandemic Risk Assessment for a Swine Influenza A Virus in Comparative Human Substrates
Padykula, I.; Damodaran, L.; Young, K. T.; Krunkosky, M.; Griffin, E. F.; North, J. F.; Neasham, P. J.; Pleiasis, V. C.; Siepker, C. L.; Stanton, J. B.; Howerth, E. W.; Bahl, J.; Kyriakis, C. S.; Tompkins, S. M.
10.1101/2024.02.24.581872 — microbiology — Posted on 2024-02-25
782 ASTROGLIOSIS AND NEUROINFLAMMATION UNDERLIE SCOLIOSIS UPON CILIA DYSFUNCTION
Djebar, M.; Anselme, I.; Pezeron, G.; Bardet, P.-L.; Cantaut-Belarif, Y.; Eschstruth, A.; Lopez-Santos, D.; Le Ribeuz, H.; Jenett, A.; Khoury, H.; Veziers, J.; Parmentier, C.; Hirschler, A.; Carapito, C.; Bachmann-Gagescu, R.; Schneider-Maunoury, S.; Vesque, C.
10.1101/2024.02.22.581530 — developmental biology — Posted on 2024-02-25
783 Enterovirus A71 adaptation to heparan sulfate comes with capsid stability tradeoff
Tee, H. K.; Mathez, G.; Cagno, V.; Antanasijevic, A.; Clement, S.; Tapparel, C.
10.1101/2024.02.23.581741 — microbiology — Posted on 2024-02-25
784 Pathologic α-Synuclein-NOD2 Interaction and RIPK2 Activation Drives Microglia-Induced Neuroinflammation in Parkinson's Disease
Ko, H.; Dawson, T. M.; Seo, B. A.; Kwon, S.-H.; Kim, D.; Kim, H.-B.; Ma, S.-X.; Gadhave, K.; Burgess, N.; Mao, X.; Rosenthal, L. S.; Redding-Ochoa, J.; Troncoso, J. C.; Lee, S.; Dawson, V. L.
10.1101/2024.02.19.580982 — neuroscience — Posted on 2024-02-25
785 Mitochondrial origins of the pressure to sleep
Sarnataro, R.; Velasco, C. D.; Monaco, N.; Kempf, A.; Miesenboeck, G.
10.1101/2024.02.23.581770 — neuroscience — Posted on 2024-02-25
787 Oncogenic Mutant p53 Sensitizes Non-Small Cell Lung Cancer Cells to Proteasome Inhibition via Oxidative Stress-Dependent Induction of Mitochondrial Apoptosis
Chougoni, K. K.; Neely, V.; Ding, B.; Oduah, E.; Lam, V.; Hu, B.; Koblinski, J. E.; Windle, B. E.; Deb, S. P.; Deb, S.; Radhakrishnan, S. K.; Harada, H.; Grossman, S. R.
10.1101/2024.02.22.581532 — cancer biology — Posted on 2024-02-25
788 Deciphering the impact of cancer cells secretome and its derived-peptide VGF on breast cancer brain metastasis
Carvalho, R.; Santos, L.; Conde, I.; Leitao, R.; Ferreira, H. R. S.; Gomes, C.; Silva, A. P.; Schmitt, F.; Carvalho-Maia, C.; Lobo, J.; Jeronimo, C.; Paredes, J.; Ribeiro, A. S.
10.1101/2024.02.22.581537 — cancer biology — Posted on 2024-02-25
792 Deep phenotypic profiling of neuroactive drugs in larval zebrafish
Gendelev, L.; Taylor, J.; Myers-Turnbull, D.; Chen, S.; McCarroll, M. N.; Arkin, M. R.; Kokel, D.; Keiser, M. J.
10.1101/2024.02.22.581657 — bioinformatics — Posted on 2024-02-25
794 The genetic landscape, gene flow and adaptation in Ladakh highlanders of trans-Himalayas
Kumar, L.; Rajpal, R.; Ahlawat, B.; Pasupuleti, N.; Konar, S.; Dwivedi, A.; Kumar, S.; Spalzin, S.; Rabyang, S.; Thangaraj, K.; Rai, N.
10.1101/2024.02.05.579041 — genetics — Posted on 2024-02-25
795 Non-cell-autonomous regulation of germline proteostasis by insulin/IGF-1 signaling via the intestinal peptide transporter PEPT-1
Muhammad, T.; Edwards, S. L.; Morphis, A. C.; Johnson, M. V.; Oliveira, V. D.; Chamera, T.; Liu, S.; Nguyen, N. G. T.; Li, J.
10.1101/2024.02.22.581543 — developmental biology — Posted on 2024-02-25
798 Ilamycins are dual inhibitors of ClpX and ClpC1 involved in proteostasis in Mycobacteria
Gao, Y.; Fang, C.; Zhou, B.; Hameed, H. M. A.; Sun, C.; Tian, X.; He, J.; Han, X.; Zhang, H.; Ju, J.; Chen, X.; Zhong, N.; Ma, J.; Xiong, X.; Zhang, T.
10.1101/2024.02.24.581832 — microbiology — Posted on 2024-02-25
799 Concurrent Ascaris infection modulates host immunity resulting in impaired control of Salmonella infection in pigs
Midha, A.; Oser, L.; Schlosser-Brandenburg, J.; Laubcshat, A.; Mugo, R. M.; Musimbi, Z. D.; Höfler, P.; Kundik, A.; Hayani, R.; Adjah, J.; Groenhagen, S.; Tieke, M. H.; Elizalde-Velazquez, L. E.; Kühl, A. A.; Klopfleisch, R.; Tedin, K.; Rausch, S.; Hartmann, S.
10.1101/2024.02.21.581410 — immunology — Posted on 2024-02-25
800 Differential cell type-specific function of the aryl hydrocarbon receptor and its repressor in diet-induced obesity and fibrosis
Graelmann, F. J.; Gondorf, F.; Majlesain, Y.; Niemann, B.; Klepac, K.; Gottschalk, M.; Mayer, M.; Iriady, I.; Hatzfeld, P.; Lindenberg, S. K.; Wunderling, K.; Thiele, C.; Abdullah, Z.; He, W.; Hiller, K.; Haendler, K.; Beyer, M. D.; Ulas, T.; Pfeifer, A.; Esser, C.; Weighardt, H.; Förster, I.; Reverte-Salisa, L.
10.1101/2024.02.22.581524 — immunology — Posted on 2024-02-25
801 Development And Characterization Of A Non-Human Primate Model Of Disseminated Synucleinopathy
Rico, A. J.; Corcho, A.; Chocarro, J.; Ariznabarreta, G.; Roda, E.; Honrubia, A.; Arnaiz Esteban, P.; Lanciego, J. L.
10.1101/2023.12.15.571818 — neuroscience — Posted on 2024-02-25
802 Cross-species modeling and enhancement of cognitive control with striatal brain stimulation
Reimer, A. E.; Dastin-van Rijn, E. M.; Kim, J.; Mensinger, M. E.; Sachse, E. M.; Wald, A.; Hoskins, E.; Singh, K.; Alpers, A.; Cooper, D.; Lo, M.-C.; de Oliveira, A. R.; Simandl, G.; Stephenson, N.; Widge, A. S.
10.1101/2024.02.16.580680 — neuroscience — Posted on 2024-02-25
803 Diagnostic of head blight and leaf blotch diseases of wheat in Sweden using a mycobiome isolation approach
Kaur, H.; Vilvert, E.; Corrales Gutierrez, M. A.; Zhan, J.; Douchkov, D.; Desiderio, F.; Velez, H.; Bourras, S.
10.1101/2024.01.09.574850 — plant biology — Posted on 2024-02-25
805 Ovarian disrupting effects and mechanisms of long- and short-chain per- and polyfluoroalkyl substances in mice
Pattarawat, P.; Zhan, T.; Fan, Y.; Zhang, J.; Yang, H.; Zhang, Y.; Moyd, S.; Douglas, N. C.; Urbanek, M.; Buckley, B.; Burdette, J.; Zhang, Q.; Kim, J.-Y. J.; Xiao, S.
10.1101/2024.02.20.581034 — pharmacology and toxicology — Posted on 2024-02-25
808 Discovery of novel compounds and target mechanisms using a high throughput, multiparametric phenotypic screen in a human neuronal model of Tuberous Sclerosis
Williams, L. A.; Ryan, S. J.; Joshi, V.; Lewarch, C.; Elder, A.; McManus, O.; Godard, P.; Sridhar, S.; Jacques, J.; Grooms, J.; Fink, J. J.; Zhang, H.; Gillard, M.; Pegurier, C.; Sabnis, Y.; Andre, V.; Steward, L.; Dedeurwaerdere, S.; Devinsky, O.; Wolff, C.; Dempsey, G. T.
10.1101/2024.02.22.581652 — neuroscience — Posted on 2024-02-25
814 Mesencephalic projections to the nucleus accumbens shell modulate value updating during probabilistic reversal learning
Zühlsdorff, K.; Piller, S.; Sala-Bayo, J.; Zhukovsky, P.; Lamla, T.; Nissen, W.; von Heimendahl, M.; Deiana, S.; Nicholson, J. R.; Robbins, T.; Alsiö, J.; Dalley, J. W.
10.1101/2024.02.24.581852 — animal behavior and cognition — Posted on 2024-02-25
815 Five-leaf generalizations of the D-statistic revealthe directionality of admixture
Leppälä, K.; da Silva Coelho, F. A.; Richter, M.; Albert, V. A.; Lindqvist, C.
10.1101/2024.02.24.581856 — genetics — Posted on 2024-02-25
816 Building predictive Markov State Models of ion channel permeation from Molecular Dynamics
Catacuzzeno, L.; Leonardi, M. V.; Franciolini, F.; Domene, C.; Michelucci, A.; Furini, S.
10.1101/2024.02.22.581422 — biophysics — Posted on 2024-02-24
818 Degradation of IKAROS prevents epigenetic progression of T cell exhaustion in a novel antigen-specific assay
Tay, T.; Bommakanti, G.; Jaensch, E.; Gorthi, A.; Reddy, I.; Hu, Y.; Zhang, R.; Doshi, A.; Tan, S. L.; Brucklacher-Waldert, V.; Prickett, L.; Kurasawa, J.; Overstreet, M.; Criscione, S.; Buenrostro, J.; Mele, D.
10.1101/2024.02.22.581548 — genomics — Posted on 2024-02-24
820 Impact of Spruce Plantation on Plant Diversity
Manuzi, V.; Balestra, S.; Gatti, P.; Losapio, G.
10.1101/2024.02.22.581586 — ecology — Posted on 2024-02-24
821 BET Degraders Reveal BRD4 Disruption of 7SK and P-TEFb is Critical for Effective Reactivation of Latent HIV in CD4+ T-cells
Turner, A.-M. W.; Bashore, F. M.; Falcinelli, S. D.; Fox, J. A.; Keller, A. L.; Fenton, A. D.; Geyer, R. F.; Allard, B.; Kirchherr, J. L.; Archin, N. M.; James, L. I.; Margolis, D. M.
10.1101/2024.02.23.581756 — molecular biology — Posted on 2024-02-24
822 Characterization of natural product inhibitors of quorum sensing in Pseudomonas aeruginosa reveals competitive inhibition of RhlR by ortho-vanillin
Woods, K. E.; Akhter, S.; Rodriguez, B. L.; Townsend, K. A.; Smith, N. C.; Wambua, A. N.; Craddock, V.; Santa, E. E.; Manson, D. E.; Abisado-Duque, R. G.; Oakley, B. R.; Hancock, L. E.; Miao, Y.; Blackwell, H. E.; Chandler, J. R.
10.1101/2024.02.24.581676 — microbiology — Posted on 2024-02-24
823 Mechanism of phage sensing and abortion by toxin-antitoxin-chaperone systems
Mets, T.; Kurata, T.; Ernits, K.; Johansson, M. J. O.; Craig, S. Z.; Evora, G. M.; Buttress, J. A.; Odai, R.; Coppieters't Wallant, K.; Nakamoto, J. A.; Shyrokova, L.; Egorov, A. A.; Doering, C. R.; Brodiazhenko, T.; Laub, M. T.; Tenson, T.; Strahl, H.; Martens, C.; Harms, A.; Garcia-Pino, A.; Atkinson, G. C.; Hauryliuk, V.
10.1101/2024.02.24.581848 — microbiology — Posted on 2024-02-24
824 Exploring the repository of de novo designed bifunctional antimicrobial peptides through deep learning
Dong, R.; Liu, R.; Liu, Z.; Liu, Y.; Zhao, G.; Li, H.; Hou, S.; Ma, X.; Kang, H.; Liu, J.; Guo, F.; Zhao, P.; Wang, J.; Wang, C.; Wu, X.; Ye, S.; Zhu, C.
10.1101/2024.02.23.581845 — microbiology — Posted on 2024-02-24
825 BTK and MMP9 regulate NLRP3 inflammasome-dependent cytokine and NET responses in primary neutrophils.
Leal, V. N. C.; Bork, F.; von Guilleaume, J. C.; Greve, C. L.; Bugl, S.; Danker, B.; Bittner, Z. A.; Grimbacher, B.; Pontillo, A.; Weber, A. N.
10.1101/2024.02.23.581733 — immunology — Posted on 2024-02-24
830 Structural Determinants for Activity of the Antidepressant Vortioxetine at Human and Rodent 5-HT3 receptors
Lopez-Sanchez, U.; Munro, L. J.; Ladefoged, L. K.; Pedersen, A. J.; Brun, C. C.; Lyngby, S. M.; Baud, D.; Pedersen, M. G.; Lummis, S. C. R.; Bang-Andersen, B.; Schiott, B.; Chipot, C.; Schoehn, G.; Neyton, J.; Dehez, F.; Nury, H.; Kristensen, A. S.
10.1101/2024.02.23.581731 — biochemistry — Posted on 2024-02-24
831 Direction-aware functional class scoring enrichment analysis of Infinium DNA methylation data
Ziemann, M.; Abeysooriya, M.; Bora, A.; Lamon, S.; Kasu, M. S.; Norris, M. W.; Wong, Y. T.; Craig, J. M.
10.1101/2024.02.22.581670 — genomics — Posted on 2024-02-24
833 Synthetic type III-E CRISPR-Cas effectors for programmable RNA-targeting
Brogan, D. J.; Dalla Benetta, E.; Wang, T.; Lin, C. P.; Chen, F.; Li, H.; Lin, C.; Komives, E. A.; Akbari, O. S.
10.1101/2024.02.23.581838 — molecular biology — Posted on 2024-02-24
834 m6A landscape is more pervasive when Trypanosoma brucei exits the cell cycle
Serra, L.; Silva Pereira, S.; Viegas, I.; Machado, H.; Lopez-Escobar, L.; Figueiredo, L. M.
10.1101/2024.02.23.581781 — molecular biology — Posted on 2024-02-24
837 Toxoplasma type II effector GRA15 has limited influence in vivo
Merritt, E. F.; Kochanowsky, J. A.; Herve, P.; Watson, A. A.; Koshy, A. A.
10.1101/2024.02.23.581829 — microbiology — Posted on 2024-02-24
838 Androgens modulate the immune profile in a mouse model of polycystic ovary syndrome
Torstensson, S.; Ascani, A.; Risal, S.; Lu, H.; Zhao, A.; Espinosa, A.; Lindgren, E.; Johansson, M. H.; Eriksson, G.; Barakat, M.; Karlsson, M. C. I.; Svensson, C.; Benrick, A.; Stener-Victorin, E.
10.1101/2024.02.22.581579 — immunology — Posted on 2024-02-24
839 Unconventional IFNω-like genes dominate the type I IFN locus and the constitutive antiviral responses in bats
Geng, R.; Wang, Q.; Yao, Y.-L.; Shen, X.-R.; Jia, J.-K.; Wang, X.; Zhu, Y.; Li, Q.; Shi, Z.-L.; Zhou, P.
10.1101/2024.02.22.581518 — immunology — Posted on 2024-02-24
840 Hypoxia disrupts circadian rhythms in astrocytes and causes synapse engulfment defects
Li, L.; Pasca, A. M.; Choi, J.; Shin, C. H.; Htun, S.; Mestan, S.; Voss, A.; Shadrach, J. L.; Puno, A.; Nagar, D.; Ramirez, N.; Rojo, D.; Lee, S. H.; Gibson, E. M.; Kaltschmidt, J. A.; Sloan, S. A.; Chung, W.-S.
10.1101/2024.02.22.581651 — neuroscience — Posted on 2024-02-24
841 Proteomics-based characterization of ribosome heterogeneity in adult mouse organs
BELIN, S.; Schaeffer, J.; Brunchault, M.-R.; Hesse, A.-M.; Decourt, C.; Combes, F.; NAWABI, H.; Coute, Y.
10.1101/2024.02.23.581691 — biochemistry — Posted on 2024-02-24
844 Molecular, Cellular, and Developmental Organization of the Mouse Vomeronasal Organ at Single Cell Resolution
Hills, M. H.; Ma, L.; Fang, A.; Chiremba, T.; Malloy, S.; Scott, A. R.; Perera, A. G.; Yu, R.
10.1101/2024.02.22.581574 — neuroscience — Posted on 2024-02-24
845 Code Multiplexed Nanocapacitor Arrays for Scalable Neural Recordings
Weaver, S.; Chen, Y.; Renz, A. F.; Choi, W.; Vyza, Y.; Schlotter, T.; Vulic, K.; Kim, D.; Atzeni, G.; Momotenko, D.; Nakatsuka, N.; Jang, T.; Vörös, J.
10.1101/2024.02.22.581578 — neuroscience — Posted on 2024-02-24
849 Graphene microelectrode arrays, 4D structured illumination microscopy, and a machine learning-based spike sorting algorithm permit the analysis of ultrastructural neuronal changes during neuronal signalling in a model of Niemann-Pick disease type C
Lu, M.; Hui, E.; Brockhoff, M.; Trauble, J.; Fernandez-Villegas, A.; Burton, O. J.; Lamb, J.; Ward, E.; Hooper, P. J.; Tadbier, W.; Laubli, N. F.; Hofmann, S.; Kaminski, C. F.; Lombardo, A.; Kaminski Schierle, G. S.
10.1101/2024.02.22.581570 — neuroscience — Posted on 2024-02-24
852 Contractility of cardiac and skeletal muscle tissue increases with environmental stiffness
Kah, D.; Lell, J.; Wach, T.; Spoerrer, M.; Dessalles, C. A.; Kraxner, J.; Wiedenmann, S.; Gerum, R. C.; Vergarajauregui, S.; Esser, T. U.; Boehringer, D.; Engel, F. B.; Thievessen, I.; Fabry, B.
10.1101/2024.02.23.581737 — biophysics — Posted on 2024-02-24
856 Large herbivores link plant phenology and abundance in arctic tundra
Post, E.; Higgins, R. C.; Boving, P. S.; John, C.; Post, M.; Kerby, J.
10.1101/2024.02.23.581818 — ecology — Posted on 2024-02-24
857 Environmental drivers of the decline of the fen orchid, Liparis loeselii
Andersen, D. K.; Ejrnaes, R.; Minter, M.; Riis, T.; Vinther, E.; Bruun, H. H.
10.1101/2024.02.22.581533 — ecology — Posted on 2024-02-24
859 A Machine Learning Framework to Identify the Correlates of Disease Severity in Acute Arbovirus Infection
Herder, V.; Caporale, M.; MacLean, O.; Pintus, D.; Huang, X.; Nomikou, K.; Palmalux, N.; Nichols, J.; Scivoli, R.; Boutell, C.; Taggart, A.; Allan, J.; Malik, H.; Ilia, G.; Gu, Q.; Ronchi, G. F.; Furnon, W.; Zientara, S.; Breard, E.; Antonucci, D.; Capista, S.; Giansante, D.; Cocco, A.; Mercante, M. T.; Di Ventura, M.; Filipe, A. D. S.; Puggioni, G.; Sevilla, N.; Stewart, M.; Ligios, C.; Palmarini, M.
10.1101/2024.02.23.581333 — microbiology — Posted on 2024-02-24
862 Design and construction towards a pan-microbial toolkit
Gilbert, C.; Crits-Christoph, A.; Ledieu-Dherbecourt, E.; Kang, S. C.; Brumwell, S. L.; Lee, H. H.; Ostrov, N.
10.1101/2024.02.23.581749 — synthetic biology — Posted on 2024-02-24
864 Nova-ST: Nano-Patterned Ultra-Dense platform for spatial transcriptomics
Poovathingal, S.; Davie, K.; Vandepoel, R.; Poulvellarie, N.; Verfaillie, A.; Corthout, N.; Aerts, S.
10.1101/2024.02.22.581576 — genomics — Posted on 2024-02-24
865 Escape from X inactivation is directly modulated by levels of Xist non-coding RNA
Hauth, A.; Panten, J.; Kneuss, E.; Picard, C.; Servant, N.; Rall, I.; Perez-Rico, Y. A.; Clerquin, L.; Servaas, N.; Villacorta, L.; Jung, F.; Luong, C.; Chang, H. Y.; Stegle, O.; Odom, D. T.; Loda, A.; heard, E.
10.1101/2024.02.22.581559 — developmental biology — Posted on 2024-02-24
866 Scywalker: scalable end-to-end data analysis workflow for nanopore single-cell transcriptome sequencing
De Rijk, P.; Watzeels, T.; Kucukali, F.; Van Dongen, J.; Faura, J.; Willems, P.; De Deyn, L.; Duchateau, L.; Grones, C.; Eekhout, T.; De Pooter, T.; Joris, G.; Rombauts, S.; De Rybel, B.; Rademakers, R.; Van Breusegem, F.; Strazisar, M.; Sleegers, K.; De Coster, W.
10.1101/2024.02.22.581508 — bioinformatics — Posted on 2024-02-24
868 Admixture with cultivated sunflower likely facilitated establishment and spread of wild sunflower (H. annuus) in Argentina
Hernandez, F.; Vercellino, R. B.; Todesco, M.; Bercovich, N.; Alvarez, D.; Brunet, J.; Presotto, A.; Rieseberg, L. H.
10.1101/2024.02.22.581669 — evolutionary biology — Posted on 2024-02-24
870 A VHL-1/HIF-1/SQRD1/COL-88 axis links extracellular matrix formation with longevity in Caenorhabditis elegans
Salgueiro, W.; Esmaillie, R.; Bohl, K.; Statzer, C.; Bharill, P.; Bargfrede, S.; Chokkalingam, M.; Neutzer, M.; Ignarski, M.; Benzing, T.; Beyer, A.; Schermer, B.; Ewald, C.; Fabretti, F.; Müller, R.-U.
10.1101/2024.02.22.581513 — genetics — Posted on 2024-02-24
871 Foveal RGCs develop altered calcium dynamics weeks after photoreceptor ablation
Xu, Z.; Kunala, K.; Murphy, P.; Puthussery, T.; McGregor, J. E.; Patak, L.
10.1101/2023.05.30.542908 — physiology — Posted on 2024-02-24
873 Decoupling of the Onset of Anharmonicity between a Protein and Its Surface Water around 200 K
Zheng, L.; Huang, J.; Tyagi, M.; Sakai, V. G.; Yamada, T.; O'Neill, H.; Zhang, Q.; Zhou, B.
10.1101/2023.10.18.562890 — biophysics — Posted on 2024-02-24
876 Antibiotic treatment does not abrogate protection against Mycobacterium tuberculosis reinfection
Ganchua, S. K.; Maiello, P.; Chao, M.; Hopkins, F.; Mugahid, D.; Lin, P. L.; Fortune, S. M.; Flynn, J. L.
10.1101/2023.12.19.570845 — microbiology — Posted on 2024-02-24
878 Development of novel tools for dissection of central versus peripheral dopamine D2-like receptor signaling in dysglycemia
Bonifazi, A.; Ellenberger, M.; Farino, Z. J.; Aslanoglou, D.; Rais, R.; Pereira, S.; Mantilla-Rivas, J. O.; Boateng, C. A.; Eshleman, A. J.; Janowsky, A.; Hahn, M. K.; Schwartz, G. J.; Slusher, B. S.; Newman, A. H.; Freyberg, Z.
10.1101/2024.02.21.581451 — neuroscience — Posted on 2024-02-24
881 Kinetochores grip microtubules with directionally asymmetric strength
Larson, J. D.; Heitkamp, N. A.; Murray, L. E.; Popchock, A. R.; Biggins, S.; Asbury, C. L.
10.1101/2024.02.22.581622 — biophysics — Posted on 2024-02-24
882 Neuroimmune changes underscore pain-associated behaviors and disc herniations in SM/J mice
Novais, E. J.; Ottone, O. K.; Brown, E. V.; Madhu, V.; Tran, V. A.; Dighe, A. S.; Solga, M. D.; Manchel, A.; Lepore, A. C.; Risbud, M. K.
10.1101/2024.02.23.581794 — cell biology — Posted on 2024-02-24
883 PLK1-Mediated Phosphorylation Cascade Activates the Mis18 Complex to Ensure Centromere Inheritance
Parashara, P.; Medina-Pritchard, B.; Abad, M. A.; Sotelo-Parrilla, P.; Thamkachy, R.; Grundei, D.; Zou, J.; Das, V.; Yan, Z.; Kelly, D. A.; McHugh, T.; Rappsilber, J.; Jeyaprakash, A. A.
10.1101/2024.02.23.581399 — cell biology — Posted on 2024-02-24
886 An age-specific platelet differentiation path from hematopoietic stem cells contributes to exacerbated thrombosis
Poscablo, D.; Worthington, A.; Smith-Berdan, S.; Manso, B.; Adili, R.; Cool, T.; Reggiardo, R.; Dahmen, S.; Beaudin, A.; Boyer, S. W.; Holinstat, M.; Forsberg, C.
10.1101/2024.02.23.581812 — cell biology — Posted on 2024-02-24
887 A series of spontaneously blinking dyes for super-resolution microscopy
Holland, K. L.; Plutkis, S. E.; Daugird, T. A.; Sau, A.; Grimm, J. B.; English, B. P.; Zheng, Q.; Dave, S.; Rahman, F.; Xie, L.; Dong, P.; Tkachuk, A. N.; Brown, T. A.; Singer, R. H.; Liu, Z. J.; Galbraith, C. G.; Musser, S. M.; Legant, W. R.; Lavis, L. D.
10.1101/2024.02.23.581625 — cell biology — Posted on 2024-02-24
889 PPTC7 antagonizes mitophagy by promoting BNIP3 and NIX degradation via SCFFBXL4
Nguyen-Dien, G. T.; Townsend, B.; Kulkarni, P.; Kozul, K.-L.; Ooi, S. S.; Eldershaw, D.; Weeratunga, S.; Liu, M.; Jones, M. J.; Millard, S. S.; Ng, D. C.; Pagano, M.; Komander, D.; Lazarou, M.; Collins, B. M.; Pagan, J. K.
10.1101/2024.02.23.581814 — cell biology — Posted on 2024-02-24
890 Predicting the direction of phenotypic difference
Gokhman, D.; Harris, K. D.; Carmi, S.; Greenbaum, G.
10.1101/2024.02.22.581566 — genetics — Posted on 2024-02-23
891 The ciliary protein C2cd3 is required for mandibular musculoskeletal tissue patterning
Brooks, E. C.; Han, S. J. Y.; Bonatto Paese, C. L.; Lewis, A. A.; Aarnio-Peterson, M.; Brugmann, S. A.
10.1101/2024.02.23.581730 — developmental biology — Posted on 2024-02-23
892 Activity-dependent regulation of vascular cholesterol metabolism acts as a negative feedback mechanism for neurovascular coupling
Profaci, C. P.; Foreman, K. L.; Spieth, L.; Coelho-Santos, V.; Berghoff, S. A.; Fontaine, J. T.; Jeffrey, D. A.; Palecek, S. P.; Shusta, E. V.; Saher, G.; Shih, A. Y.; Dabertrand, F.; Daneman, R.
10.1101/2024.02.23.581685 — neuroscience — Posted on 2024-02-23
894 Emergence of a synergistic scaffold in the brains of human infants
Varley, T. F.; Sporns, O.; Stevenson, N. J.; Welch, M. G.; Myers, M. M.; Vanhatalo, S.; Tokariev, A.
10.1101/2024.02.23.581375 — neuroscience — Posted on 2024-02-23
896 Vitamin B12 variants structure soil microbial communities despite soil's vast reservoir of B12.
Hallberg, Z. F.; Nicolas, A. M.; Alvarez-Aponte, Z. I.; Mok, K. C.; Sieradzki, E. T.; Pett-Ridge, J.; Banfield, J.; Carlson, H. K.; Firestone, M. K.; Taga, M. E.
10.1101/2024.02.12.580003 — microbiology — Posted on 2024-02-23
897 Chromosome-level genome assembly and annotation of the social amoeba Dictyostelium firmibasis
Edelbroek, B.; Kjellin, J.; Jerlstrom-Hultqvist, J.; Koskiniemi, S.; Soderbom, F.
10.1101/2024.02.22.581529 — genomics — Posted on 2024-02-23
900 Macrophages undergo functionally significant reprogramming of nucleotide metabolism upon classical activation
John, S. V.; Seim, G. L.; Erazo-Flores, B. J.; Steill, J.; Freeman, J.; Votava, J. A.; Arp, N. L.; Qing, X.; Stewart, R.; Knoll, L. J.; Fan, J.
10.1101/2023.12.27.573447 — cell biology — Posted on 2024-02-23
902 Rational protein engineering to enhance MHC-independent T cell receptors
Chang, J.; Landmann, J. H.; Chang, T.-C.; Tenzin, Y.; Warrington, J. M.; Selli, M. E.; Ritchey, J.; Hsu, Y.-S.; Slade, M.; Gupta, D. K.; DiPersio, J. F.; Singh, N.
10.1101/2024.02.22.581571 — immunology — Posted on 2024-02-23
905 Laboratory evolution reveals transcriptional mechanisms underlying thermal adaptation of Escherichia coli
Rychel, K.; Chen, K.; Catoiu, E. A.; Olson, C. A.; Sandberg, T. E.; Gao, Y.; Xu, S.; Hefner, Y.; Szubin, R.; Patel, A.; Feist, A. M.; Palsson, B.
10.1101/2024.02.22.581624 — systems biology — Posted on 2024-02-23
907 The αC-β4 loop controls the allosteric cooperativity between nucleotide and substrate in the catalytic subunit of protein kinase A
Olivieri, C.; Wang, Y.; Walker, C.; Subrahmanian, M. V.; Ha, K. N.; Bernlohr, D. A.; Gao, J.; Camilloni, C.; Vendruscolo, M.; Taylor, S. S.; Veglia, G.
10.1101/2023.09.12.557419 — biophysics — Posted on 2024-02-23
908 High-resolution single-particle imaging at 100-200 keV with the Gatan Alpine direct electron detector.
Chan, L. M.; Courteau, B. J.; Maker, A.; Wu, M.; Basanta, B.; Mehmood, H.; Bulkley, D.; Joyce, D.; Lee, B. C.; Mick, S.; Gulati, S.; Lander, G. C.; Verba, K. A.
10.1101/2024.02.14.580363 — biophysics — Posted on 2024-02-23
910 Short-chain fatty acids propionate and butyrate control growth and differentiation linked to cellular metabolism
Nshanian, M.; Geller, B. S.; Gruber, J. J.; Chleilat, F.; Lancaster, S.; Camarillo, J. M.; Kelleher, N. L.; Zhao, Y.; Snyder, M. P.
10.1101/2024.01.11.575111 — genetics — Posted on 2024-02-23
911 Nuclear instance segmentation and tracking for preimplantation mouse embryos
Nunley, H.; Shao, B.; Denberg, D.; Grover, P.; Singh, J.; Avdeeva, M.; Joyce, B.; Kim-Yip, R.; Kohrman, A.; Biswas, A.; Watters, A.; Gal, Z.; Kickuth, A.; Chalifoux, M.; Shvartsman, S.; Brown, L.; Posfai, E.
10.1101/2023.03.14.532646 — developmental biology — Posted on 2024-02-23
912 Park7 deletion leads to age- and sex-specific transcriptome changes involving NRF2-CYP1B1 axis in mouse midbrain astrocytes
Helgueta, S.; Heurtaux, T.; Sciortino, A.; Gui, Y.; Ohnmacht, J.; Mencke, P.; Boussaad, I.; Halder, R.; Garcia, P.; Krueger, R.; Mittelbronn, M.; Buttini, M.; Sauter, T.; Sinkkonen, L.
10.1101/2024.02.23.581743 — molecular biology — Posted on 2024-02-23
915 The double-edged role of FASII regulator FabT in Streptococcus pyogenes infection
Lambert, C.; Bachmann, C.; Gaillard, M.; Hautcoeur, A.; Wongdontree, P.; Gloux, K.; Guilbert, T.; Mechats, C.; Prost, B.; Solgadi, A.; Abreu, S.; Andrieu, M.; Poyart, C.; Gruss, A.; FOUET, A.
10.1101/2023.06.07.543851 — microbiology — Posted on 2024-02-23
916 Interleukin-1 receptor antagonist is a conserved driver of tuberculosis
Kotov, D. I.; Lee, O. V.; Ji, D. X.; Jaye, D. L.; Suliman, S.; Gabay, C.; Vance, R. E.
10.1101/2023.10.27.564420 — immunology — Posted on 2024-02-23
920 Stability from subspace rotations and traveling waves
Batabyal, T.; Brincat, S. L.; Donoghue, J. A.; Lundqvist, M.; Mahnke, M. K.; Miller, E. K.
10.1101/2024.02.19.581020 — neuroscience — Posted on 2024-02-23
921 Enhancement of brain atlases with laminar coordinate systems: Flatmaps and barrel column annotations
Bolanos-Puchet, S.; Teska, A.; Hernando, J. B.; Lu, H.; Romani, A.; Schürmann, F.; Reimann, M. W.
10.1101/2023.08.24.554204 — neuroscience — Posted on 2024-02-23
923 A multi-symptomatic model of heroin use disorder in rats reveals distinct behavioral profiles and neuronal correlates of heroin vulnerability versus resiliency
Kuhn, B. N.; Cannella, N.; Crow, A.; Lunerti, V.; Gupta, A.; Walterhouse, S.; Allen, C.; Chalhoub, R.; Dereschewitz, E.; Roberts, A.; Cockerham, M.; Beeson, A.; Nall, R.; Palmer, A. A.; Hardiman, G.; Solberg-Woods, L.; Chung, D.; Ciccocioppo, R.; Kalivas, P.
10.1101/2024.02.22.581440 — neuroscience — Posted on 2024-02-23
925 Conserved neural dynamics and computations across species in olfaction
Ling, D.; Hanson Moss, E.; Smith, C. L.; Deng, F.; Kroeger, R.; Reimer, J. L.; Raman, B.; Arenkiel, B. R.
10.1101/2023.04.24.538157 — neuroscience — Posted on 2024-02-23
928 Elucidating TolC Protein Dynamics: Structural Shifts Facilitate Efflux Mediated β-lactam Resistance
Kantarcioglu, I.; Gaszek, I. K.; Guclu, T. F.; Yildiz, M. S.; Atilgan, A. R.; Toprak, E.; ATILGAN, C.
10.1101/2024.02.22.581573 — biophysics — Posted on 2024-02-23
930 Modern Insights into Muscle Glycogen Phosphorylase Activity
Kiriaev, L.; Oakhill, J. S.; Tiong, C. F.; Seto, J. T.; Crossman, V. G.; Quinlan, K. G. R.; North, K. N.; Houweling, P. J.; Ling, N. X. Y.
10.1101/2024.02.22.581477 — biochemistry — Posted on 2024-02-23
932 Wild communities of Morpho butterflies reveal Spiroplasma endosymbiont with inflated genome size and peculiar evolution
Jonathan, F.; Lopez-Villavicencio, M.; Vincent, D.; Rachel, F.; Camilo, S.; Karina, L. S.-B.; Patrick, B.; Andre, V. L. F.; Carolina, P.-D.; Violaine, L.
10.1101/2024.02.22.581604 — evolutionary biology — Posted on 2024-02-23
933 Improved Serodiagnosis of Trypanosoma vivax Infections in Cattle Reveals Higher Infection Rates in the Livestock Regions of Argentina
Bontempi, I. A.; Arias, D. G.; Castro, G. V.; Peverengo, L. M.; Diaz, G. F.; Allassia, M.; Greif, G.; Marcipar, I.
10.1101/2024.02.22.581515 — ecology — Posted on 2024-02-23
934 Automated plankton monitoring suggests a key role of microzooplankton and temperature for predicting dynamics of phytoplankton size classes
Merkli, S.; Merz, E.; Reyes, M.; Ntetsika, P.; Dennis, S.; Isles, P. D. F.; Kyathanahally, S.; Baity-Jesi, M.; To, S.-W.; Merico, A.; Pomati, F.
10.1101/2024.02.23.581723 — ecology — Posted on 2024-02-23
937 Comparative pollinator conservation potential of coffee agroforestry relative to coffee monoculture and tropical rainforest in the DR Congo
Depecker, J.; Vandelook, F.; Jordaens, K.; Dorchin, A.; Ntumba, B.; Broeckhoven, I.; Dhed'a, B.; Devriese, A.; Deckers, L.; Stoffelen, P.; Honnay, O.
10.1101/2024.02.23.581744 — ecology — Posted on 2024-02-23
942 Interferons and tuft cell numbers are bottlenecks for persistent murine norovirus infection
Aggarwal, S.; Walker, F. C.; Weagley, J. S.; McCune, B. T.; Wu, X.; Schreifer, L.; Makimaa, H.; Lawrence, D.; Sridhar, P.; Baldridge, M. T.
10.1101/2024.02.22.581634 — microbiology — Posted on 2024-02-23
945 Food Fermentation in Space Is Possible, Distinctive, and Beneficial
Coblentz, M.; Evans, J. D.; Kothe, C. I.; Mak, T.; Rodriguez Valeron, N.; Chwalek, P.; Wejendorp, K.; Garg, S.; Pless, L.; Mak, S.; Sorensen, P. M.; Jahn, L. J.; Ekblaw, A.
10.1101/2024.02.23.579929 — microbiology — Posted on 2024-02-23
949 Investigating the ability of music to induce calm in young adults.
Shepherd, D.; Pedersen, M.; Vashista, G.; Kercher, A.; Hautus, M. J.
10.1101/2024.02.22.581668 — neuroscience — Posted on 2024-02-23
950 HippoMaps: Multiscale cartography of the human hippocampal formation
DeKraker, J.; Cabalo, D. G.; Royer, J.; Khan, A. R.; Karat, B.; Benkarim, O.; Rodriguez-Cruces, R.; Frauscher, B.; Pana, R.; Hansen, J. Y.; Misic, B.; Valk, S. L.; Kirschner, M.; Bernasconi, A.; Bernasconi, N.; Muenzing, S.; Axer, M.; Amunts, K.; Evans, A. C.; Bernhardt, B. C.
10.1101/2024.02.23.581734 — neuroscience — Posted on 2024-02-23
957 Mechanistic Analysis of Riboswitch Ligand Interactions Provides Insights into Pharmacological Control over Gene Expression
Parmar, S.; Bume, D. D.; Connelly, C. M.; Boer, R. E.; Prestwood, P. R.; Wang, Z.; Labuhn, H.; Sinnadurai, K.; Feri, A.; Ouellet, J.; Homan, P.; Numata, T.; Schneekloth, J. S.
10.1101/2024.02.23.581746 — biochemistry — Posted on 2024-02-23
958 A specific phosphorylation-dependent conformational switch of SARS-CoV-2 nucleoprotein inhibits RNA binding
Botova, M.; Camacho-Zarco, A. R.; Tognetti, J.; Bessa, L. M.; Guseva, S.; Mikkola, E.; Salvi, N.; Maurin, D.; Herrmann, T.; Blackledge, M.
10.1101/2024.02.22.579423 — biochemistry — Posted on 2024-02-23
959 The maternal microbiome modifies adverse effects of protein undernutrition on offspring neurobehavioral impairment in mice
Coley, E.; Lum, G.; Pronovost, G.; Ozcan, E.; Yu, K.; Mcdermott, J.; chakhoyan, A.; Goldman, E.; Vuong, H.; Paramo, J.; Chu, A.; Calkins, K.; Hsiao, E. Y.
10.1101/2024.02.22.581439 — animal behavior and cognition — Posted on 2024-02-23
960 Trends in genome diversity of small populations under a conservation program: a case study of two French chicken breeds
Bortoluzzi, C.; Restoux, G.; Rouger, R.; Desnoues, B.; Petitjean, F.; Bosse, M.; Tixier-Boichard, M.
10.1101/2024.02.22.581528 — genomics — Posted on 2024-02-23
961 A comprehensive personal omics clinical interpreter based on genomic and transcriptomic profiles
Liu, Y.; Chen, Q.; Chen, Q.; Sang, L.; Wang, Y.; Shi, L.; Zheng, Y.; Guo, L.; Yu, Y.
10.1101/2024.02.22.581482 — genomics — Posted on 2024-02-23
962 An egg sabotaging mechanism drives non-Mendelian transmission in mice
Clark, F. E.; Greenberg, N. L.; Silva, D. M. Z. A.; Trimm, E.; Skinner, M.; Walton, R. Z.; Rosin, L. F.; Lampson, M. A.; Akera, T.
10.1101/2024.02.22.581453 — genetics — Posted on 2024-02-23
963 Thymidine Phosphorylase Mediates SARS-CoV-2 Spike Protein Enhanced Thrombosis in K18-hACE2TG Mice
Roytenberg, R.; Yue, H.; DeHart, A.; Kim, E.; Bai, F.; Kim, Y.; Denning, K.; Kwei, A.; Zhang, Q.; Liu, J.; Zheng, L.; Li, W.
10.1101/2024.02.23.581661 — cell biology — Posted on 2024-02-23
966 Avian influenza virus circulation and immunity in a wild urban duck population prior to and during a highly pathogenic H5N1 outbreak
Wight, J.; Rahman, I.; Wallace, H. L.; Cunningham, J. T.; Roul, S.; Roberston, G. J.; Russell, R. S.; Xu, W.; Zhmendak, D.; Alkie, T. N.; Berhane, Y.; Hargan, K. E.; Lang, A. S.
10.1101/2024.02.22.581693 — microbiology — Posted on 2024-02-23
969 TKI-conditioned immunotherapy using uv-inactivated reovirus promotes survival in hepatocellular carcinoma, mediated by cytotoxic CD4+ T-cells
Hughes, R.; Moran, A.; Scott, K. J.; Appleton, E.; Bentham, M. J.; Ilett, E.; Melcher, A.; Macdonald, A.; Samson, A.; Griffin, S.
10.1101/2024.02.23.581738 — immunology — Posted on 2024-02-23
970 A site-wise reliability analysis of the ABCD diffusion fractional anisotropy data, impact of the scanner and analytical pipeline
Pan, Y.; Hong, L. E.; Acheson, A.; Thompson, P.; Jahanshad, N.; Yu, J.; Chen, C.; Ma, T.; Liu, H.-L.; Fieremans, E.; Kochunov, P.; Chen, S.
10.1101/2024.02.21.581460 — neuroscience — Posted on 2024-02-23
973 Olive Flowering dependence on winter temperatures - linking empirical results to a dynamic model
Smoly, I.; Elbaz, H.; Engelen, C.; Wechsler, T.; Elbaz, G.; Ben Ari, G.; Samach, A.; Friedlander, T.
10.1101/2024.02.21.581335 — plant biology — Posted on 2024-02-23
975 Mechanical loading reveals an intrinsic cardiomyocyte stiffness contribution to diastolic dysfunction in murine cardiometabolic disease
Janssens, J. V.; Raaijmakers, A. J. A.; Koutsifeli, P.; Weeks, K. L.; Bell, J. R.; Van Eyk, J. E.; Curl, C. L.; Mellor, K. M.; Delbridge, L. M. D.
10.1101/2024.02.21.581448 — physiology — Posted on 2024-02-23
976 Identifying cancer cells from calling single-nucleotide variants in scRNA-seq data
Marot-Lassauzaie, V.; Beneyto-Calabuig, S.; Obermayer, B.; Velten, L.; Beule, D.; Haghverdi, L.
10.1101/2024.02.21.581377 — bioinformatics — Posted on 2024-02-23
977 Peptide Amphiphiles Hitchhike on Endogenous Biomolecules for Enhanced Cancer Imaging and Therapy
Fischer, J. M.; Stewart, M.; Dai, M.; Drennan, S.; Holland, S.; Quentel, A.; Sabuncu, S.; Kingston, B. R.; Dengos, I.; Xiang, L.; Bonic, K.; Goncalves, F.; Yi, X.; Ranganathan, S.; Branchaud, B. P.; Muldoon, L. L.; Barajas, R. F.; Yildirim, A.
10.1101/2024.02.21.580762 — bioengineering — Posted on 2024-02-23
978 CYpHER: Catalytic extracellular targeted protein degradation with high potency and durable effect
Crook, Z. R.; Sevilla, G. P.; Young, P.; Girard, E. J.; Phi, T.-D.; Howard, M.; Olson, J. M.; Nairn, N. W.
10.1101/2024.02.21.581471 — bioengineering — Posted on 2024-02-23
980 Genetic polymorphisms of Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3) gene in African American kidney transplant recipients are associated with post-transplant graft failure
Sun, Z.; Yi, Z.; Wei, C.; Wang, W.; Cravedi, P.; Tedla, F.; Ward, S. C.; Azeloglu, E.; Schrider, D. R.; Li, Y.; Ali, S.; Ren, T.; Liu, S.; Liang, D.; Fu, J.; Liu, T.; Li, H.; Xi, C.; Vy, T. H.; Mosoyan, G.; Sun, Q.; Kumar, A.; Zhang, Z.; Farouk, S.; Campbell, K.; Ochando, J.; Lee, K.; Coca, S.; Xiang, J.; Connolly, P.; Gallon, L.; Colvin, R.; Menon, M.; Nadkarni, G.; He, J. C.; Kraft, M.; Jiang, X.; Zhang, X.; Zhang, W.; Chen, S.-h.; Heeger, P.; Zhang, W.
10.1101/2024.02.21.581383 — genetics — Posted on 2024-02-23
984 DDR1 regulates RUNX1-CBFβ to control breast stem cell differentiation
Trepicchio, C.; Rauner, G.; Traugh, N.; Parrish, M.; Mal, Y.; Fein, D. E. C.; Kuperwasser, C.
10.1101/2024.02.21.581255 — developmental biology — Posted on 2024-02-23
985 Probabilistic Inference on Virtual Brain Models of Disorders
HASHEMI, M.; ZIAEE-MEHR, A.; WOODMAN, M.; PETKOSKI, S.; JIRSA, V.
10.1101/2024.02.21.581243 — neuroscience — Posted on 2024-02-23
986 Transient DREADD manipulation of the dorsal Dentate Gyrus in rats impairs disambiguation of similar place-outcome associations
Lim, J.; Souiki, A.; Ahmad, P.; Oomen, C. A.; Huis in 't Veld, G. J.; Lansink, C. S.; Pennartz, C.; Olcese, U.
10.1101/2024.02.20.581173 — neuroscience — Posted on 2024-02-23
988 Development of novel tools for dissection of central versus peripheral dopamine D2-like receptor signaling in dysglycemia
Bonifazi, A.; Ellenberger, M.; Farino, Z. J.; Aslanoglou, D.; Rais, R.; Pereira, S.; Mantilla-Rivas, J. O.; Boateng, C. A.; Eshleman, A. J.; Janowsky, A.; Hahn, M. K.; Schwartz, G. J.; Slusher, B. S.; Freyberg, Z.
10.1101/2024.02.21.581451 — neuroscience — Posted on 2024-02-23
989 Ephrin-B2 promotes nociceptive plasticity and hyperalgesic priming through EphB2-MNK-eIF4E signaling in both mice and humans
David, E.; Yousuf, M. S.; Mei, H.-R.; Jain, A.; Krishnagiri, S.; Srikanth, K. D.; Dussor, G.; Dalva, M. B.; Price, T. J.
10.1101/2024.02.21.581414 — neuroscience — Posted on 2024-02-23
990 Contracted Functional Connectivity Profiles in Autism
Weber, C. F.; Kebets, V.; Benkarim, O.; Lariviere, S.; Wang, Y.; Ngo, A.; Jiang, H.; Chai, X. J.; Park, B.-y.; Milham, M.; Di Martino, A.; Valk, S. L.; Hong, S.-J.; Bernhardt, B.
10.1101/2024.02.21.581260 — neuroscience — Posted on 2024-02-23
991 Monkeys engage in visual simulation to solve complex problems
Ahuja, A.; Yusif Rodriguez, N.; Ashok, A. K.; Serre, T.; Desrochers, T.; Sheinberg, D.
10.1101/2024.02.21.581495 — neuroscience — Posted on 2024-02-23
992 The Dorsal Column Nuclei Scales Mechanical Allodynia During Neuropathic Pain
Upadhyay, A.; Gradwell, M. A.; Vajtay, T. J.; Conner, J.; Sayal, A. A.; Azadegan, C.; Patel, K. R.; Thackray, J. K.; Bohic, M.; Imai, F.; Ogundare, S. O.; Yoshida, Y.; Abdus-Saboor, I.; Azim, E.; Abraira, V. E. G.
10.1101/2024.02.20.581208 — neuroscience — Posted on 2024-02-23
993 Cholesterol modifies Nav1.7 - an in-silico and in-vitro analysis
Albani, S.; Eswaran, V. S. B.; Piergentili, A.; Souza, P. C. T. d.; Lampert, A.; Rossetti, G.
10.1101/2024.02.21.581348 — physiology — Posted on 2024-02-23
995 Metabolic shift to serine pathway induced by lipids confers oncogenic properties in non-transformed breast cells
Eduardo, M. B.; Cottone, G.; McCloskey, C. W.; Liu, S.; Zappia, M. P.; Benevolenskaya, E. V.; Islam, A. B. M. M. K.; Frolov, M. V.; Palma, F. R.; Gao, P.; Setya, J.; Gao, H.; Xuei, X.; Khokha, R.; Locasale, J.; Bonini, M. G.; Chandel, N. S.; Khan, S. A.; Clare, S. E.
10.1101/2024.02.21.581404 — cancer biology — Posted on 2024-02-23
997 Protein-structure-sensitive mid-infrared optoacoustic microscopy enables label-free assessment of drug therapy in myeloma cells
Gasparin, F.; Tietje, M. R.; Katab, E.; Nurdinova, A.; Yuan, T.; Chmyrov, A.; Uluc, N.; Jüstel, D.; Bassermann, F.; Ntziachristos, V.; Pleitez, M. A.
10.1101/2024.02.21.581391 — biophysics — Posted on 2024-02-23
998 Imaging and quantification of prostate cancer-associated bone by polarization-sensitive optical coherence tomography
Zhou, C.; JUNG, N.; XU, S.; GUERSETTI, F. E.; Lu, X.; WANG, Q.; LIANG, D.; MORRISSEY, C.; COREY, E.; TRUE, L.; Wang, R.; Tang, S.; Cox, M. E.
10.1101/2024.02.21.581336 — biophysics — Posted on 2024-02-23
1003 Large-scale characterization of cell niches in spatial atlases using bio-inspired graph learning
Birk, S.; Bonafonte-Pardas, I.; Feriz, A. M.; Boxall, A.; Agirre, E.; Memi, F.; Maguza, A.; Fan, R.; Castelo-Branco, G.; Bayraktar, O.; Theis, F. J.; Talavera-Lopez, C.; Lotfollahi, M.
10.1101/2024.02.21.581428 — bioinformatics — Posted on 2024-02-23
1007 Spherical Echo-Planar Time-resolved Imaging (sEPTI) for rapid 3D quantitative T2* and Susceptibility imaging
Wang, N.; Liao, C.; Cao, X.; Nishimura, M.; Brackenier, Y.; Yurt, M.; Gao, M.; Abraham, D.; Alkan, C.; Iyer, S. S.; Zhou, Z.; Kerr, A.; Haldar, J.; Setsompop, K.
10.1101/2024.02.21.581459 — bioengineering — Posted on 2024-02-23
1008 Revealing In Situ Molecular Profiles of Glomerular Cell Types and Substructures with Integrated Imaging Mass Spectrometry and Multiplexed Immunofluorescence Microscopy
Esselman, A. B.; Moser, F. A.; Tideman, L.; Migas, L. G.; Djambazova, K. V.; Colley, M. E.; Pingry, E. L.; Patterson, N. H.; Farrow, M. A.; Yang, H.; Fogo, A. B.; de Caestecker, M.; Van de Plas, R.; Spraggins, J. M.
10.1101/2024.02.21.581450 — biochemistry — Posted on 2024-02-23
1011 A pan-tissue, pan-disease compendium of human orphan genes
Singh, U.; Haltom, J.; Guarnieri, J.; Li, J.; Seetharam, A.; Beheshti, A.; Aronow, B.; Wurtele, E. S.
10.1101/2024.02.21.581488 — evolutionary biology — Posted on 2024-02-23
1013 Epigenetic regulation by TET1 in gene-environmental interactions influencing susceptibility to congenital malformations
van der Veer, B. K.; Chen, L.; Tsaniras, S. C.; Brangers, W.; Chen, Q.; Schroiff, M.; Custers, C.; Kwak, H. H. M.; Khoueiry, R.; Cabrera, R.; Gross, S. S.; Finnell, R. H.; Lei, Y.; Koh, K. P.
10.1101/2024.02.21.581196 — developmental biology — Posted on 2024-02-23
1015 Mutational Analysis of an Antimalarial Drug Target PfATP4
Rachuri, S.; Nepal, B.; Shukla, A.; Ramanathan, A. A.; Morrisey, J. M.; Daly, T. M.; Mather, M. W.; Bergman, L. W.; Kortagere, S.; Vaidya, A. B.
10.1101/2024.02.21.581445 — microbiology — Posted on 2024-02-23
1017 Impact of Glycan Depletion, Glycan Debranching and Increased Glycan Charge on HIV-1 Neutralization Sensitivity and Immunogenicity
D'Addabbo, A.; Tong, T.; Crooks, E.; Osawa, K.; Xu, J.; Thomas, A.; Allen, J.; Crispin, M.; Binley, J. M.
10.1101/2024.02.20.581329 — immunology — Posted on 2024-02-23
1018 Label free metabolic imaging to enhance the efficacy of Chimeric Antigen Receptor T cell therapy
Pham, D. L.; Cappabianca, D.; Forsberg, M.; Weaver, C.; Mueller, K. P.; Tommasi, A.; Vidugiriene, J.; Lauer, A.; Sylvester, K.; Bugel, M.; Capitini, C. M.; Saha, K.; Skala, M. C.
10.1101/2024.02.20.581240 — immunology — Posted on 2024-02-23
1019 Responses of neurons in macaque V4 to object and texture images
Lieber, J. D.; Oleskiw, T. D.; Simoncelli, E. P.; Movshon, J. A.
10.1101/2024.02.20.581273 — neuroscience — Posted on 2024-02-23
1021 Age-related dysregulation of the retinal transcriptome in African turquoise killifish
Bergmans, S.; Noel, N. C.; Masin, L.; Harding, E. G.; Krzywanska, A. M.; De Schutter, J. D.; Ayana, R.; Hu, C.-K.; Arckens, L.; Ruzycki, P. A.; Clark, B. S.; MacDonald, R. B.; Moons, L.
10.1101/2024.02.21.581372 — neuroscience — Posted on 2024-02-23
1022 ACE1 knockout in neurons selectively dysregulates the hippocampal renin angiotensin system and causes vascular loss
Jeon, S.; Salvo, M. A.; Alia, A. O.; Popovic, J.; Zagardo, M.; Chandra, S.; Nassan, M.; Gate, D.; Vassar, R.; Cuddy, L.
10.1101/2024.02.21.581402 — neuroscience — Posted on 2024-02-23
1023 Gustatory-neuron-supplied R-spondin-2 is required for taste bud replenishment
Xu, J.; de Araujo, A.; Xi, R.; Lin, X.; Lu, C.; Zhou, M.; Hankenson, K. D.; Margolskee, R. F.; Matsumoto, I.; de Lartigue, G.; Choi, M.; Jiang, P.
10.1101/2024.02.21.581408 — neuroscience — Posted on 2024-02-23
1028 Targeted NAD+ Delivery for Intimal Hyperplasia and Re-endothelialization: A Novel Anti-restenotic Therapy Approach
Yin, L.; Tong, Y.; Islam, Z. H.; Zhang, K.; Xie, R.; Burger, J.; Hoyt, N.; Kent, E. W.; Marcum, W. A.; Johnston, C.; Kanchetty, R.; Tetz, Z.; Stanisic, S.; Huang, Y.; Guo, L.-W.; Gong, S.; Wang, B.
10.1101/2024.02.20.581249 — pathology — Posted on 2024-02-23
1029 p300 KAT regulates SOX10 stability and function in human melanoma
Waddell, A.; Grbic, N.; Leibowitz, K.; Wyant, W. A.; Choudhury, S.; Park, K.; Collard, M.; Cole, P. A.; Alani, R. M.
10.1101/2024.02.20.581224 — cancer biology — Posted on 2024-02-23
1030 The MYCN 5' UTR as a therapeutic target in neuroblastoma
Volegova, M. P.; Brown, L. E.; Banerjee, U.; Dries, R.; Sharma, B.; Kennedy, A.; Porco, J. A.; George, R. E.
10.1101/2024.02.20.581230 — cancer biology — Posted on 2024-02-23
1033 MU-BRAIN: MUltiethnic Brain Rna-seq for Alzheimer INitiative
Yang, Z.; Cieza, B.; Reyes-Dumeyer, D.; Lee, A.; Ma, Y.; Yilmaz, E.; Lantigua, R.; Miller, G.; Brown, L.; Honig, L.; Ciener, B.; Leskinin, S.; Sivakumar, S.; Vardarajan, B.; Dugger, B.; Jin, L.-W.; Murray, M.; Dickson, D.; Rissman, R.; Hiniker, A.; Pericak-Vance, M.; Vance, J.; Foroud, T.; Kizil, C.; Teich, A.; Mayeux, R.; Tosto, G.
10.1101/2024.02.20.581250 — genetics — Posted on 2024-02-23
1037 An analysis of contractile and protrusive cell behaviours at the superficial surface of the zebrafish neural plate
Araya, C.; Farlie, F.; Moon, L.; Rookyard, C.; Allison, L.; Vizcay-Barrena, G.; Fleck, R.; Tada, M.; Clarke, J.
10.1101/2024.02.20.581322 — developmental biology — Posted on 2024-02-23
1038 Normative and individual, non-normative intrinsic networks and the transition to impaired cognition
Zhang, Q.; Hudgins, S.; Struck, A. F.; Ankeeta, A.; Javidi, S. S.; Sperling, M. R.; Hermann, B. P.; Tracy, J. I.
10.1101/2024.02.20.581233 — neuroscience — Posted on 2024-02-23
1039 Superoxide enters neurons via LRRC8A-containing volume-regulated anion channels
Harris, K.; Uruk, G.; Won, S. J.; Mai, N.; Baxter, P.; Everaerts, K.; Sah, R.; Swanson, R. A.
10.1101/2024.02.20.580732 — neuroscience — Posted on 2024-02-23
1040 Gene Regulatory Network topology governs resistance and treatment escape in glioma stem-like cells
Park, J. H.; Hothi, P.; Lopez Garcia de Lomana, A.; Pan, M.; Calder, R.; Turkarslan, S.; Wu, W.-J.; Lee, H.; Patel, A. P.; Cobbs, C.; Huang, S.; Baliga, N. S.
10.1101/2024.02.02.578510 — systems biology — Posted on 2024-02-23
1041 Multilevel proteomic profiling of colorectal adenocarcinoma cell differentiation to characterize an intestinal epithelial model
Fekete, E. E.; Wang, A.; Creskey, M.; Cummings, S. E.; Lavoie, J. R.; Ning, Z.; Li, J.; Figeys, D.; Chen, R.; ZHANG, X.
10.1101/2024.02.19.581096 — systems biology — Posted on 2024-02-23
1042 Enable, Empower, Succeed: Harnessing Open Science for Antimicrobial Resistance Containment
Founou, L. L.; Lawal, O. U.; Djiyou, A.; Odih, E. E.; Amoako, D. G.; Fadanka, S.; Aworh, M. K.; Lukhele, S.; Nikolic, D.; Matimba, A.; Founou, R. C.
10.1101/2024.02.20.580892 — scientific communication and education — Posted on 2024-02-23
1043 Single-cell and single-nucleus RNA-sequencing from paired normal-adenocarcinoma lung samples provides both common and discordant biological insights.
Renaut, S.; Armero, V. S.; Boudreau, D. K.; Gaudreault, N.; Desmeules, P.; Theriault, S.; Mathieu, P.; Joubert, P.; Bosse, Y.
10.1101/2024.02.20.581199 — cancer biology — Posted on 2024-02-23
1046 Engineering a three-dimensional multilayer multicellular model of endometrial cancer for high throughput drug screening and novel treatment methods
Cadena, I. A.; Rowlands, C.; Buchanan, M. R.; Jenne, M. A.; Keefe, B.; Almer, A.; Obasi, N.; Harris, C. G.; Rochefort, W. E.; Givens, B. E.; Fogg, K. C.
10.1101/2024.02.20.581239 — bioengineering — Posted on 2024-02-23
1047 Deep mutational scanning of Pneumocystis jirovecii dihydrofolate reductase reveals allosteric mechanism of resistance to an antifolate
Rouleau, F. D.; Dube, A. K.; Gagnon-Arsenault, I.; Dibyachintan, S.; Pageau, A.; Despres, P. C.; Lagüe, P.; Landry, C. R.
10.1101/2023.09.27.559786 — biochemistry — Posted on 2024-02-23
1048 Negative Life Events and Epigenetic Ageing: a Study in the Netherlands Twin Register
Gonggrijp, B. M. A.; van de Weijer, S. G. A.; Bijleveld, C. C. J. H.; Boomsma, D. I.; van Dongen, J.
10.1101/2024.02.20.581138 — genetics — Posted on 2024-02-23
1049 Recovery of a learned behavior despite partial restoration of neuronal dynamics after chronic inactivation of inhibitory neurons
Torok, Z.; Luebbert, L.; Feldman, J.; Duffy, A.; Nevue, A.; Wongso, S.; Mello, C.; Fairhall, A.; Pachter, L.; Gonzalez, W. G.; Lois, C.
10.1101/2023.05.17.541057 — neuroscience — Posted on 2024-02-23
1051 Symplasmic phloem loading and sub-cellular transport in storage roots are key factors for carbon allocation in cassava
Rüscher, D.; Vasina, V. V.; Knoblauch, J.; Bellin, L.; Pommerrenig, B.; Alseekh, S.; Fernie, A. R.; Neuhaus, H. E.; Knoblauch, M.; Sonnewald, U.; Zierer, W.
10.1101/2024.02.21.581442 — plant biology — Posted on 2024-02-23
1052 Molecular mechanisms of seasonal brain shrinkage and regrowth inSorex araneus
Thomas, W. R.; Dechmann, D. K. N.; Nieland, J.; Elverfeldt, D.; Carlson, D.; Baldoni, C.; Holm-Jacobsen, J.; Muturi, M.; Corthals, A.; Davalos, L.
10.1101/2023.10.02.560485 — genetics — Posted on 2024-02-23
1053 Land-use impacts on plant functional diversity throughout Europe
Rosa, F.; van Bodegom, P.; Hellweg, S.; Pfister, S.; Biurrun, I.; Boch, S.; Chytry, M.; Custerevska, R.; Dalle Fratte, M.; Damasceno, G.; Garbolino, E.; Lenoir, J.; Ozinga, W. A.; Penuelas, J.; Sabatini, F. M.; Schrodt, F.; Uogintas, D.; Byun, C.; Dolezal, J.; Dziuba, T.; Herault, B.; Martin-Fores, I.; Niinemets, U.; Peyre, G.; Scherer, L.
10.1101/2024.02.21.580945 — ecology — Posted on 2024-02-23
1054 Synaptopodin is required for efficient intercellular spread by bacterial pathogens
Vickery, J. M.; Toperzer, J. D.; Raab, J. E.; Hamilton, D. J.; Harju, T. B.; Huynh, T. N.; Zhou, L.; Lenz, L. L.; Colgan, S. P.; Russo, B. C.
10.1101/2023.04.25.537990 — microbiology — Posted on 2024-02-23
1057 3D in vitro modeling of the exocrine pancreatic unit using tomographic volumetric bioprinting
Sgarminato, V.; Madrid-Wolff, J.; Boniface, A.; Ciardelli, G.; Tonda-Turo, C.; Moser, C.
10.1101/2023.01.23.525142 — bioengineering — Posted on 2024-02-23
1058 Skeletal progenitor LRP1 deficiency causes severe and persistent skeletal defects with WNT/planar cell polarity dysregulation.
Alhashmi, M.; Gremida, A. M.; Maharana, S. K.; Antonaci, M.; Kerr, A.; Al-Maslamani, N. A.; Liu, K.; Meschis, M. M.; Sutherland, H.; Wilson, P.; Clegg, P.; Wheeler, G. N.; van 't Hof, R. J.; Bou-Gharios, G.; Yamamoto, K.
10.1101/2023.07.11.548556 — developmental biology — Posted on 2024-02-23
1059 Cryo-electron tomography suggests tubulin chaperones form a subset of microtubule lumenal particles with a role in maintaining neuronal microtubules
Chakraborty, S.; Martinez-Sanchez, A.; Beck, F.; Toro-Nahuelpan, M.; Hwang, I.-Y.; Noh, K.-M.; Baumeister, W.; Mahamid, J.
10.1101/2022.07.28.501854 — cell biology — Posted on 2024-02-23
1062 Rejuvenating silicon probes for acute electrophysiology
Shoup, A.; Porwal, N.; Fakharian, M. A.; Hage, P.; Orozco, S. P.; Shadmehr, R.
10.1101/2024.02.20.581222 — neuroscience — Posted on 2024-02-23
1069 Prenatal VEGF Nano-Delivery Reverses Congenital Diaphragmatic Hernia-Associated Pulmonary Abnormalities
Loukogeorgakis, S.; Michielin, F.; Shibuya, S.; Al-Juffali, N.; Jimenez, J.; Allen-Hyttinen, J.; Eastwood, P.; Alhendi, A.; Davidson, J.; Naldi, E.; Maghsoudlou, P.; Tedeschi, A.; Khalaf, S.; Khabbush, A.; Plate, M.; Fachin, C.; Dos Santos Dias, A.; Sindhawani, N.; Scaglioni, D.; Xenakis, T.; Sebire, N.; Giomo, M.; Eaton, S.; Toelen, J.; Luni, C.; Pavan, P.; Carmeliet, P.; Russo, F.; Janes, S.; Nikolic, M.; Elvassore, N.; Deprest, J.; De Coppi, P.
10.1101/2024.02.20.581170 — bioengineering — Posted on 2024-02-23
1072 Evolution and inhibition of the FIKK effector kinase family in P. falciparum
Belda, H.; Bradley, D.; Christodoulou, E.; Nofal, S. D.; Broncel, M.; Jones, D. A.; Davies, H.; Bertran, M. T.; Purkiss, A. G.; Ogrodowicz, R. W.; Joshi, D.; O'Reilly, N.; Walport, L.; Claessens, A.; Powell, A.; House, D.; Kjaer, S.; Landry, C. R.; Treeck, M.
10.1101/2024.02.22.581535 — microbiology — Posted on 2024-02-23
1074 Local Delivery of Soluble Fractalkine (CX3CL1) Peptide Restore Ribbon Synapses After Noise-Induced Cochlear Synaptopathy
Manickam, V. N.; Maity, S.; Murali, S. V.; Gawande, D. Y.; Stothert, A. R.; Batalkina, L. V.; Cardona, A.; Kaur, T.
10.1101/2024.02.20.581182 — neuroscience — Posted on 2024-02-23
1076 Estradiol elicits distinct firing patterns in arcuate nucleus kisspeptin neurons of females through altering ion channel conductances
Qiu, J.; Voliotis, M.; Bosch, M. A.; Li, X. F.; Zweifel, L. S.; Tsaneva-Atanasova, K.; O'Byrne, K.; Ronnekleiv, O. K.; Kelly, M. J.
10.1101/2024.02.20.581121 — neuroscience — Posted on 2024-02-23
1077 Genetic barcodes for ash (Fraxinus) species and generation of new wide hybrids
Plumb, W.; Kelly, L.; Mullender, J.; Powell, R.; Gorriz, M. N.; Carey, D.; Mason, M.; Crowther, W.; Koch, J.; Douglas, G.; Buggs, R.
10.1101/2024.02.19.581010 — plant biology — Posted on 2024-02-23
1079 Interpretable deep learning reveals the sequence rules of Hippo signaling
Dalal, K.; McAnany, C.; Weilert, M.; McKinney, M. C.; Krueger, S.; Zeitlinger, J.
10.1101/2024.02.22.580842 — genomics — Posted on 2024-02-23
1084 Agrobacterium-mediated Cuscuta campestris transformation as a tool for understanding plant-plant interactions
Adhikari, S.; Mudalige, A.; Phillips, L.; Lee, H.; Bernal, V.; Gruszewski, H.; Westwood, J.; Park, S.-Y.
10.1101/2024.02.23.581736 — plant biology — Posted on 2024-02-23
1085 Photoreceptor-induced LHL4 protects photosystem II in Chlamydomonas reinhardtii
Dannay, M.; Bertin, C.; Cavallari, E.; Albanese, P.; Tolleter, D.; Giustini, C.; Menneteau, M.; Brugiere, S.; Coute, Y.; Finazzi, G.; Demarsy, E.; Ulm, R.; Allorent, G.
10.1101/2024.02.23.581703 — plant biology — Posted on 2024-02-23
1086 Role of PLK1 in the epigenetic maintenance of centromeres
Conti, D.; Esposito Verza, A.; Pesenti, M. E.; Cmentowski, V.; Vetter, I. R.; Pan, D.; Musacchio, A.
10.1101/2024.02.23.581696 — cell biology — Posted on 2024-02-23
1087 Molecular and Cellular Mechanisms of Teneurin Signaling in Synaptic Partner Matching
Xu, C.; Li, Z.; Lyu, C.; Hu, Y.; McLaughlin, C.; Wong, K. K. L.; Xie, Q.; Luginbuhl, D. J.; Li, H.; Udeshi, N.; Svinkina, T.; Mani, D. R.; Carr, S. A.; Han, S.; Li, T.; Li, Y.; Guajardo, R.; Ting, A. Y.; Li, J.; Luo, L.
10.1101/2024.02.23.581689 — neuroscience — Posted on 2024-02-23
1088 Dynamic representation of appetitive and aversive stimuli in nucleus accumbens shell D1- and D2-medium spiny neurons
Domingues, A. V.; Carvalho, T. T. A.; Martins, G. J.; Correia, R.; Coimbra, B.; Goncalves, R.; Wezik, M.; Gaspar, R.; Pinto, L.; Sousa, N.; Costa, R. M.; Soares-Cunha, C.; Rodrigues, A. J.
10.1101/2024.02.22.581563 — neuroscience — Posted on 2024-02-23
1090 A chromatic feature detector in the retina signals visual context changes
Hoefling, L.; Szatko, K. P.; Behrens, C.; Qiu, Y.; Deng, Y.; Klindt, D. A.; Jessen, Z.; Schwartz, G. S.; Bethge, M.; Berens, P.; Franke, K.; Ecker, A. S.; Euler, T.
10.1101/2022.11.30.518492 — neuroscience — Posted on 2024-02-23
1091 The ZmHSF20-ZmHSF4-ZmCesA2 module regulates heat stress tolerance in maize
Li, Z.; Li, Z.; Ji, Y.; Wang, C.; Wang, S.; Shi, Y.; Le, J.; Zhang, M.
10.1101/2024.02.21.581499 — plant biology — Posted on 2024-02-23
1093 Allosteric modulation by the fatty acid site in the glycosylated SARS-CoV-2 spike
Oliveira, A. S. F.; Kearns, F. L.; Rosenfeld, M. A.; Casalino, L. F.; Berger, I.; Schaffitzel, C.; Davidson, A. D.; Amaro, R. E.; Mulholland, A. J.
10.1101/2023.11.06.565757 — biochemistry — Posted on 2024-02-23
1094 Gene Therapy Mediates Therapeutic Improvement in Cardiac Hypertrophy and Survival in a Murine Model of MYBPC3-Associated Cardiomyopathy
Lombardi, L. M.; Greer-Short, A.; Greenwood, A.; Leon, E. C.; Qureshi, T. N.; von Kraut, K.; Wong, J.; Reid, C. A.; Cheng, Z.; Easter, E.; Yang, J.; Ho, J.; Steltzer, S.; Budan, A.; Cho, M.; Feathers, C.; Chung, T. W.; Rodriguez, N.; Jones, S.; Alleyne-Levy, C.; Liu, J.; Jing, F.; Prince, W. S.; Lin, J.; Ivey, K. N.; Tingley, W. G.; Hoey, T.
10.1101/2024.02.19.581102 — genetics — Posted on 2024-02-23
1095 MaizeCODE reveals bi-directionally expressed enhancers that harbor molecular signatures of maize domestication.
Cahn, J.; Regulski, M.; Lynn, J.; Ernst, E.; de Santis Alves, C.; Ramakrishnan, S.; Chougule, K.; Wei, S.; Lu, Z.; Xu, X.; Drenkow, J.; Kramer, M.; Seetharam, A.; Hufford, M. B.; McCombie, W. R.; Ware, D.; Jackson, D.; Schatz, M. C.; Gingeras, T. R.; Martienssen, R. A.
10.1101/2024.02.22.581585 — plant biology — Posted on 2024-02-23
1097 Ubiquitin-mediated stabilization of SlPsbS regulates low night temperature tolerance in tomatoes
Lu, J.; Yu, J.; Liu, P.; Gu, J.; Chen, Y.; Zhang, T.; Li, J.; Wang, T.; Yang, W.; Lin, R.; Wang, F.; Qi, M.; Li, T.; Liu, Y.
10.1101/2024.02.21.581502 — plant biology — Posted on 2024-02-23
1098 Exploring the Viral Landscape of Saffron through Metatranscriptomic Analysis
Martinez-Fajardo, C.; Navarro-Simarro, P.; Morote, L.; Rubio-Moraga, A.; Mondejar-Lopez, M.; Niza, E.; Argandona, J.; Ahrazem, O.; Gomez-Gomez, L.; Lopez-Jimenez, A. J.
10.1101/2024.02.22.581521 — plant biology — Posted on 2024-02-23
1102 Microencapsulation of mesenchymal stromal cells in covalent alginate hydrogels for cell therapy
Ambrosino, M.; Nativel, F.; Boyer, C.; Lagneau, N.; Loll, F.; Halgand, B.; Djouad, F.; Renard, D.; Tessier, A.; Guicheux, J.; Delplace, V.; Le Visage, C.
10.1101/2023.11.27.568852 — bioengineering — Posted on 2024-02-23
1103 Pleiotropic effects of a recessive COL1A2 mutation occurring in a mouse model of severe osteogenesis imperfecta
Corcelli, M.; Sagar, R.; Petzendorfer, E.; Hasan, M. M.; de Vries, H. I.; van Dijk, F. S.; David, A. L.; Guillot, P. V.
10.1101/2024.02.15.580510 — genetics — Posted on 2024-02-23
1105 Targeting a specific motor control process reveals an age-related compensation that adapts movement to gravity environment
MATHIEU, R.; Chambellant, F.; Thomas, E.; Papaxanthis, C.; Hilt, P.; Manckoundia, P.; Mourey, F.; Gaveau, J.
10.1101/2024.02.16.576683 — neuroscience — Posted on 2024-02-23
1107 No Replication of Direct Neuronal Activity-related (DIANA) fMRI in Anesthetized Mice
Choi, S.-H.; Im, G. H.; Choi, S.; Yu, X.; Bandettini, P. A.; Menon, R. S.; Kim, S.-G.
10.1101/2023.05.26.542419 — neuroscience — Posted on 2024-02-23
1108 Intermittent fasting promotes type 3 innate lymphoid cells secreting IL-22 contributing to the beigeing of white adipose tissue
Chen, H.; Sun, L.; Feng, L.; Han, X.; Zhang, Y.; Zhai, W.; Zhang, Z.; Mulholland, M.; Zhang, W.; Yin, Y.
10.1101/2023.08.29.555436 — physiology — Posted on 2024-02-23
1109 A ribosome-associating chaperone mediates GTP-driven vectorial folding of nascent eEF1A
Sabbarini, I.; Reif, D.; Park, K.; McQuown, A.; Nelliat, A.; Trejtnar, C.; Dotsch, V.; Shakhnovich, E.; Murray, A.; Denic, V.
10.1101/2024.02.22.581594 — biochemistry — Posted on 2024-02-23
1113 Functional identification of soluble uric acid as an endogenous inhibitor of CD38
Wen, S.; Arakawa, H.; Yokoyama, S.; Shirasaka, Y.; Higashida, H.; Tamai, I.
10.1101/2023.06.03.543541 — immunology — Posted on 2024-02-23
1114 Light-Guided Rabies Virus Tracing for Neural Circuit Analysis
Zhang, S.; Ma, Y.; Ngamkanjanarat, W.; Takahashi, S.; Gibbs, D.; Coleman, T.; Doan, S.; Kyriakakis, P.
10.1101/2023.03.04.531104 — neuroscience — Posted on 2024-02-23
1120 Generic rules of lumen nucleation and fusion in epithelial organoids
Lu, L.; Fuji, K.; Guyomar, T.; Lieb, M.; Tanida, S.; Nonomura, M.; Hiraiwa, T.; Alcheikh, Y.; Yennek, S.; Petzold, H.; Martin-Lemaitre, C.; Grapin-Botton, A.; Honigmann, A.; Sano, M.; Riveline, D.
10.1101/2024.02.20.581158 — biophysics — Posted on 2024-02-23
1124 Charting the Cannabis plant chemical space with computational metabolomics
Myoli, A.; Choene, M.; Kappo, A. P.; Madala, N. E.; van der Hooft, J. J. J.; Tugizimana, F.
10.1101/2024.02.21.581363 — systems biology — Posted on 2024-02-22
1125 Haplotype-resolved genome and population genomics of the threatened garden dormouse in Europe
Byerly, P.; von Thaden, A.; Leushkin, E.; Hilgers, L.; Liu, S.; Winter, S.; Schell, T.; Buechner, S.; Meinig, H.; Lang, J.; Famira-Parcsetich, E.; Stubbe, S.; Gerheim, C.; Ben-Hamadou, A.; Bolz, H.; Betz, C.; Greve, C.; Mouton, A.; Bertolino, S.; Verbeylen, G.; Briner, T.; Vinciguerra, L.; Mueller, S.; Nowack, C.; Hiller, M.
10.1101/2024.02.21.581346 — genomics — Posted on 2024-02-22
1130 Molecular confirmation of Anopheles stephensi in the Al Hudaydah Governorate, Yemen, 2021-2022.
Assada, M.; Al-Hadi, M.; Esmail, M. A.; Al-Jurban, J.; Alkawri, A.; Shamsan, A.; Gomein, P.; Samake, J. N.; Aljasari, A.; Awash, A. A.; Al Eryani, S. M.; Carter, T. E.
10.1101/2024.02.22.577782 — genetics — Posted on 2024-02-22
1131 Blockade of Interleukin-6 (IL-6) Signaling in Dedifferentiated Liposarcoma (DDLPS) Decreases Mouse Double Minute 2 (MDM2) Oncogenicity via Alternative Splicing
Zewdu, A.; Braggio, D.; Lopez, G.; Batte, K.; Khurshid, S.; Costas de Faria, F.; Bid, H.; Koller, D.; Casadei, L.; Ladner, K.; Wang, D.; Grignol, V.; Iwenofu, O. H.; Chandler, D.; Guttridge, D.; Pollock, R.
10.1101/2024.02.21.581397 — molecular biology — Posted on 2024-02-22
1132 The Apurinic/Apyrimidinic Endodeoxyribonuclease 1 is an RNA G-quadruplex binding protein and regulates miR-92b expression in cancer cells
Bellina, A.; Malfatti, M. C.; Salgado, G.; Fleming, A. M.; Antoniali, G.; Gualandi, N.; La Manna, S.; Marasco, D.; Dassi, E.; Burrows, C. J.; Tell, G.
10.1101/2024.02.22.581538 — molecular biology — Posted on 2024-02-22
1134 Simultaneous protein and RNA analysis in single extracellular vesicles, including viruses: SPIRFISH
Troyer, Z.; Gololobova, O.; Koppula, A.; Liao, Z.; Horns, F.; Elowitz, M. B.; Tosar, J. P.; Batish, M.; Witwer, K. W.
10.1101/2024.02.21.581401 — molecular biology — Posted on 2024-02-22
1135 Skeletal muscle effects of antisense oligonucleotides targeting glycogen synthase 1 in a mouse model of Pompe disease
Weiss, L.; Carrer, M.; Shmara, A.; Cheng, C.; Yin, H.; Ta, L.; Boock, V.; Fazeli, Y.; Chang, M.; Paguio, M.; Lee, J.; Yu, H.; Martin, A.; Raben, N.; Weiss, J.; Grossman, T.; Jafar-nejad, P.; Kimonis, V.
10.1101/2024.02.22.580414 — molecular biology — Posted on 2024-02-22
1137 Human MX1 induces the cytoplasmic sequestration of neo-synthesized influenza A virus vRNPs
McKellar, J.; Garcia de Gracia, F.; Aube, C.; Chaves Valadao, A. L.; Tauziet, M.; Arnaud-Arnould, M.; Rebendenne, A.; Neyret, A.; Labaronne, E.; Ricci, E. P.; Delaval, B.; Gaudin, R.; Naffakh, N.; Gallois-Montbrun, S.; Moncorge, O.; Goujon, C.
10.1101/2024.02.22.581565 — microbiology — Posted on 2024-02-22
1138 Development of radial frequency pattern perception in macaque monkeys
Rodriguez Deliz, C. L.; Lee, G.; Bushnell, B.; Majaj, N. J.; Movshon, J. A.; Kiorpes, L.
10.1101/2024.02.21.581393 — neuroscience — Posted on 2024-02-22
1139 Sensory perception of fluctuating light in Arabidopsis
Belmonte, A.; Tissot, N.; Rabinovich, A.; Ploschuk, E.; Crocco, C.; Ulm, R.; Casal, J. J.
10.1101/2024.02.21.581400 — plant biology — Posted on 2024-02-22
1140 The polyamine transporter ATP13A3 mediates DFMO-induced polyamine uptake in neuroblastoma
Azfar, M.; Gao, W.; Van den Haute, C.; Xiao, L.; Karsa, M.; Pandher, R.; Ronca, E.; Bongers, A.; Karsa, A.; Spurling, D.; Guo, X.; Mayoh, C.; Burns, M. R.; Verhelst, S. H. L.; Norris, M. D.; Haber, M.; Vangheluwe, P.; Somers, K.
10.1101/2024.02.20.581161 — cancer biology — Posted on 2024-02-22
1141 In-cell structure and snapshots of copia retrotransposons in intact tissue by cryo-electron tomography
Klumpe, S.; Senti, K. A.; Beck, F.; Sachweh, J.; Hampoelz, B.; Ronchi, P.; Yeroslaviz, A.; Briggs, J.; Brennecke, J.; Beck, M.; Plitzko, J. M.
10.1101/2024.02.21.581285 — biophysics — Posted on 2024-02-22
1145 Trapped in translocation: Stalling of XPD on a crosslinked DNA substrate
Kuper, J.; Hove, T.; Maidl, S.; Sauer, F.; Kempf, M.; Greiter, E.; Neitz, H.; Hoebartner, C.; Kisker, C.
10.1101/2024.02.20.581127 — biochemistry — Posted on 2024-02-22
1146 Arabidopsis Gluconolactonase, the First Enzyme Involved in Ascorbate Biosynthesis Localized in the Chloroplast Protects Plants from Light Stress.
Yactayo-Chang, J. P.; Nepal, N.; Aboobucker, S. I.; Medina-Jimenez, K.; Wilkie, A.; Teoh, T. K.; Wilson, G. A.; LORENCE, A.
10.1101/2024.02.22.578673 — biochemistry — Posted on 2024-02-22
1150 Land-use impacts on plant functional diversity throughout Europe
Rosa, F.; Hellweg, S.; Pfister, S.; van Bodegom, P.; Biurrun, I.; Boch, S.; Byun, C.; Chytry, M.; Custerevska, R.; Dalle Fratte, M.; Damasceno, G.; Dolezal, J.; Dziuba, T.; Garbolino, E.; Herault, B.; Lenoir, J.; Martin-Fores, I.; Niinemets, U.; Ozinga, W. A.; Penuelas, J.; Peyre, G.; Sabatini, F. M.; Schrodt, F.; Uogintas, D.; Scherer, L.
10.1101/2024.02.21.580945 — ecology — Posted on 2024-02-22
1157 Protein aggregation is a consequence of the dormancy-inducing membrane toxin TisB in Escherichia coli
Leinberger, F. H.; Cassidy, L.; Edelmann, D.; Schmid, N. E.; Blumenkamp, P.; Schmidt, S.; Natriashvili, A.; Ulbrich, M. H.; Tholey, A.; Koch, H.-G.; Berghoff, B. A.
10.1101/2024.02.22.581605 — microbiology — Posted on 2024-02-22
1158 Spatial analysis reveals combinative role for natural killer and CD8 T cells in antitumor immunity despite profound MHC class I loss in non-small cell lung cancer
Wessel, R. E.; Ageeb, N.; Obeid, J. M.; Mauldin, I.; Goundry, K. A.; Hossain, M.; Lehman, C.; Gentzler, R. D.; Wages, N. A.; Slingluff, C. L.; Bullock, T. N. J.; Dolatshahi, S.; Brown, M. G.
10.1101/2024.02.20.581048 — immunology — Posted on 2024-02-22
1159 Human Alveolar and Monocyte-derived Human Macrophage Responses to Mycobacterium tuberculosis
Campo, M.; Dill-McFarland, K.; Peterson, G.; Benson, B.; Skerrett, S.; Hawn, T.
10.1101/2024.02.20.581265 — immunology — Posted on 2024-02-22
1160 CD4+ T Cell Depletion Before Primary Dengue and/or Secondary Zika Infection Reveals Mechanistic Correlates of Antibody Functionality in Rhesus Macaques.
Serrano-Collazo, C.; Miranda, A. M.; Cruz, L. A.; Henein, S.; Sanchez-Rosado, M. R.; Alvarez, L.; Arana, T.; Martinez, M. I.; Roman, C.; Burgos, A.; de Silva, A. M.; Sariol, C. A.
10.1101/2024.02.22.580962 — immunology — Posted on 2024-02-22
1164 Graspable foods and tools elicit similar responses in visual cortex
Ritchie, J. B.; Andrews, S. B.; Vaziri-Pashkam, M.; Baker, C. I.
10.1101/2024.02.20.581258 — neuroscience — Posted on 2024-02-22
1165 Asiatic acid improves mitochondrial function, activates antioxidant response in the mouse brain and improves cognitive function in beta-amyloid overexpressing mice.
Varada, S.; Chamberlin, S. R.; Bui, L.; Brandes, M. S.; Gladen-Kolarksy, N.; Harris, C. J.; Hack, W.; Brumbach, B. H.; Quinn, J. F.; Gray, N. E.
10.1101/2024.02.21.581270 — neuroscience — Posted on 2024-02-22
1166 Microglia are not required for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism
Profaci, C. P.; Harvey, S. S.; Bajc, K.; Zhang, T. Z.; Zhang, A. Z.; Nemec, K. M.; McKinsey, G. L.; Longworth, A.; McMullen, T. P.; Arnold, T. D.; Lawson, D. A.; Bennett, F. C.; Davalos, D.; Daneman, R.
10.1101/2024.02.20.580754 — neuroscience — Posted on 2024-02-22
1167 Pangenome mining of the Streptomyces genus redefines their biosynthetic potential
Mohie, O. S.; Jorgensen, T. S.; Booth, T. J.; Charusanti, P.; Phaneuf, P. V.; Weber, T.; Palsson, B. O.
10.1101/2024.02.20.581055 — systems biology — Posted on 2024-02-22
1169 Efficient cloning of genes for wheat yield component traits from QTLs via sequencing of the RIL population
Zhang, M.; Han, X.; Wang, H.; Sun, J.; Guo, B.; Gao, M.; Xu, H.; Zhang, G.; Li, H.; Cao, X.; Li, N.; Xu, Y.; Wu, Q.; Wang, C.; Zhang, G.; Yuan, Y.; Man, J.; Pu, Y.; Lv, G.; Qu, C.; Sun, J.; Cheng, X.; Dong, X.; Kong, F.; Zhao, Y.; An, Y.; Yuan, Y.; Guo, Y.; Li, S.
10.1101/2024.02.22.574000 — plant biology — Posted on 2024-02-22
1170 Age-dependent miR156-targeted SPLs are required for extrafloral nectary development in Passiflora spp.
Soares, J. R.; Robledo, K. J. M.; Souza, V. C.; Dias, L. L. L.; Silva, L. A. S.; Silveira, E. C.; Souza, C. d. S.; Sousa, E. S.; Sodrzeieski, P. A.; Sarmiento, Y. C. G.; Matos, E. M.; Falcao, T. C. d. A.; Fialho, L. d. S.; Guimaraes, V. M.; Viccini, L. F.; Pierdona, F. G.; Romanel, E.; Fouracre, J.; Otoni, W. C.; Nogueira, F.
10.1101/2024.02.20.581215 — plant biology — Posted on 2024-02-22
1174 CDKN1B (p27kip1) enhances drug tolerant persister CTCs by restricting polyploidy following mitotic inhibitors.
Horwitz, E.; Dubash, T. D.; Szabolcs, A.; Wittner, B. S.; Kreuzer, J.; Morris, R.; Bardia, A.; Chirn, B.; Wiley, D.; Che, D.; Russel, H. C.; Lopez, X. I. H.; Fox, D. B.; Antmen, E.; Ting, D. T.; Haas, W.; Sade-Feldman, M.; Maheswaran, S.; Haber, D. A.
10.1101/2024.02.20.581202 — cancer biology — Posted on 2024-02-22
1175 Time Resolved Inspection of Ionizable-Lipid Facilitated Lipid Nanoparticle Disintegration and Cargo Release at an Endosomal Membrane Mimic
Aliakbarinodehi, N.; Niederkofler, S.; Olsen, E.; Jing, Y.; Emilsson, G.; Sjoberg, M.; Agnarsson, B.; Lindfors, L.; Hook, F.
10.1101/2024.02.22.580934 — biophysics — Posted on 2024-02-22
1177 Nanobody-targeted conditional antimicrobial therapeutics
Ngambenjawong, C.; Ko, H.; Pishesha, N.; Ploegh, H. L.; Bhatia, S. N.
10.1101/2024.02.20.580917 — bioengineering — Posted on 2024-02-22
1178 Plasmalogen oxidation induces the generation of excited molecules and electrophilic lipid species
Faria, R. L.; Prado, F. M.; Junqueira, H. C.; Fabiano, K. C.; Diniz, L. R.; Baptista, M. S.; Di Mascio, P.; Miyamoto, S.
10.1101/2024.02.22.581635 — biochemistry — Posted on 2024-02-22
1180 Coordination of cytochrome bc1 complex assembly at MICOS
Zerbes, R. M.; Colina-Tenorio, L.; Bohnert, M.; Peikert, C. D.; von der Malsburg, K.; Mehnert, C. S.; Perschil, I.; Klar, R.; van der Klei, I. J.; Oeljeklaus, S.; Warscheid, B.; Rampelt, H.; van der Laan, M.
10.1101/2024.02.22.580370 — biochemistry — Posted on 2024-02-22
1181 A ribosome-associating chaperone mediates GTP-driven vectorial folding of nascent eEF1A
Denic, V.; Sabbarini, I.; Reif, D.; Park, K.; McQuown, A.; Nelliat, A.; Trejtnar, C.; Dotsch, V.; Shakhnovich, E.; Murray, A.
10.1101/2024.02.22.581594 — biochemistry — Posted on 2024-02-22
1182 A genetically-encoded nanobody sensor reveals conformational diversity in beta-arrestins orchestrated by distinct seven transmembrane receptors
Sarma, P.; Markov, V. N.; Zaidi, N.; Dalal, A.; Mishra, S.; Yadav, M. K.; Mahajan, G.; Roy, N.; Miclea, P.; Lazar, J.; SHUKLA, A. K.
10.1101/2024.02.21.581355 — biochemistry — Posted on 2024-02-22
1183 Metabolic Quadrivalency in RSeT Human Embryonic Stem Cells
Chen, K. G.; Park, K.; Maric, D.; Johnson, K. R.; Robey, P. G.; Mallon, B. S.
10.1101/2024.02.21.581486 — biochemistry — Posted on 2024-02-22
1184 The evolution of reduced facilitation in a four-species bacterial community
Piccardi, P.; Ulrich, E.; Garcia-Garcera, M.; Di Martino, R.; Testa, S. E. A.; Mitri, S.
10.1101/2024.02.22.581583 — evolutionary biology — Posted on 2024-02-22
1188 Extracellular electron transfer genes expressed by candidate flocking bacteria in cable bacteria sediment
Lustermans, J. J.; Sereika, M.; Burdorf, L. D.; Albertsen, M.; Schramm, A.; Marshall, I. P.
10.1101/2024.02.22.581617 — microbiology — Posted on 2024-02-22
1191 An efficient in vivo-inducible CRISPR interference system for group A Streptococcus genetic analysis and pathogenesis studies
Bjanes, E.; Stream, A.; Gibson, P. S.; Bravo, A. M.; Dahesh, S.; Baker, J. L.; Varble, A.; Nizet, V.; Veening, J.-W.
10.1101/2024.02.22.581527 — microbiology — Posted on 2024-02-22
1194 Automated high-throughput biological sex identification from archaeological human dental enamel using targeted proteomics
Koenig, C.; Bortel, P.; Paterson, R. S.; Rendl, B.; Madupe, P. P.; Troche, G. B.; Hermann, N. V.; Martinez de Pinillos, M.; Martinon-Torres, M.; Mularczyk, S.; Jorkov, M. L. S.; Gerner, C.; Kanz, F.; Martinez-Val, A.; Cappellini, E.; Olsen, J. V.
10.1101/2024.02.20.581140 — biochemistry — Posted on 2024-02-22
1195 Environmental and Historical Determinants of African Horse Sickness: Insights from Predictive Modeling
Kim, K.; Xu, T.; Kannan Villalan, A.; Chi, T.; Yu, X.; Jin, M.; Wu, R.; Ni, G.; Sui, S.; Wang, Z.; Wang, X.
10.1101/2024.02.20.581150 — ecology — Posted on 2024-02-22
1196 Food entrainment in mice leads to sex- and organ-specific responses in nutrient metabolism
Di Natale, M. R.; McQuade, R.; Hunne, B. L.; Koo, A.; Ringuet, M.; Coles, T.; Fothergill, L.; Furness, J. B.; Oparija-Rogenmozere, L.
10.1101/2024.02.20.580958 — molecular biology — Posted on 2024-02-22
1200 London taxi drivers exploit neighbourhood boundaries for hierarchical route planning
Griesbauer, E.-M.; Fernandez Velasco, P.; Coutrot, A.; Wiener, J. M.; Morley, J. G.; McNamee, D.; Manley, E.; Spiers, H. J.
10.1101/2024.02.20.581139 — neuroscience — Posted on 2024-02-22
1201 Busted: maternal modifiers of the triploid block involved in seed size control.
Akinmusola, R. Y.; Kilsby, H.; Wilkins, C.-A.; Cevik, V.; Scott, R.; Doughty, J.
10.1101/2024.02.20.581014 — plant biology — Posted on 2024-02-22
1204 Enhanced cardiac mitochondrial biogenesis by nitro-oleic acid remedies diastolic dysfunction in a mouse model of heart failure with preserved ejection fraction
Mueller, M.; Schubert, T.; Welke, C.; Schulz, T. J.; Patschkowski, T.; Maske, T.; Lengenfelder, L. A.; Landwehrjohann, L.; Donhauser, E.; Vogt, E. T.; Stratmann, B.; Hense, J.; Luedtke, S.; Duefer, M.; Tolstik, E.; Dierks, J.; Hormann, F.-L.; Heiles, S.; Lorenz, K.; Reil, J.-C.; Schopfer, F. J.; Freeman, B. A.; Rudolph, V.; Schlomann, U.; Klinke, A.
10.1101/2024.02.20.581137 — pathology — Posted on 2024-02-22
1206 Common methods of making giant vesicles (except emulsion techniques) capture intended lipid ratios
Weakly, H. M. J.; Wilson, K. J.; Goetz, G. J.; Pruitt, E. L.; Li, A.; Xu, L.; Keller, S. L.
10.1101/2024.02.21.581444 — biophysics — Posted on 2024-02-22
1208 Soft Tissue Mechanics in Hip Distraction after Total Knee Arthroplasty: A Finite Element Analysis
Soehnlen, S. M.; Sadeqi, S.; Kumaran, Y.; Tripathi, S.; Jones, R. K.; Sohn, D. H.; Goel, V. K.
10.1101/2024.02.13.580129 — bioengineering — Posted on 2024-02-22
1209 Multi-modal Phantom Experiments, mimicking Flow through the Mitral Heart Valve
Christierson, L.; Frieberg, P.; Lala, T.; Toger, J.; Liuba, P.; Revstedt, J.; Isaksson, H.; Hakacova, N.
10.1101/2024.02.20.581131 — bioengineering — Posted on 2024-02-22
1210 The Complete Sequence and Comparative Analysis of Ape Sex Chromosomes
Makova, K. D.; Pickett, B. D.; Harris, R. S.; Hartley, G. A.; Cechova, M.; Pal, K.; Nurk, S.; Yoo, D.; Li, Q.; Hebbar, P.; McGrath, B. C.; Antonacci, F.; Aubel, M.; Biddanda, A.; Borchers, M.; Bornberg-Bauer, E.; Bouffard, G. G.; Brooks, S. Y.; Carbone, L.; Carrel, L.; Carroll, A.; Chang, P.-C.; Chin, C.-S.; Cook, D. E.; Craig, S. J. C.; de Gennaro, L.; Diekhans, M.; Dutra, A.; Garcia, G. H.; Grady, P. G. S.; Green, R. E.; Haddad, D.; Hallast, P.; Harvey, W. T.; Hickey, G.; Hillis, D. A.; Hoyt, S. J.; Jeong, H.; Kamali, K.; Pond, S. L. K.; LaPolice, T. M.; Lee, C.; Lewis, A. P.; Loh, Y.-H. E.;
10.1101/2023.11.30.569198 — genomics — Posted on 2024-02-22
1213 Plk3 Regulates Bacteremia and Supports Sepsis
Kostyak, J.; Sarojini, S. S.; Naik, M.; Dai, W.; Michael, J. V.; McKenzie, S.; Naik, U. P.
10.1101/2024.02.19.581105 — immunology — Posted on 2024-02-22
1216 A Systematically Optimized Miniaturized Mesoscope (SOMM) for large-scale calcium imaging in freely moving mice
Zhang, Y.; Yuan, L.; Wu, J.; Noebauer, T.; Zhang, R.; Xiao, G.; Wang, M.; Xie, H.; Dai, Q.; Vaziri, A.
10.1101/2024.02.19.581043 — neuroscience — Posted on 2024-02-22
1221 Multiparameter Quantitative Analyses of Diagnostic Cells in Brain Tissues from Tuberous Sclerosis Complex
Arceneaux, J. S.; Brockman, A.; Khurana, R.; Chalkley, M.-B. L.; Geben, L. C.; Vestal, M.; Zafar, M.; Weatherspoon, S.; Mobley, B. C.; Ess, K. C.; Ihrie, R. A.
10.1101/2024.02.19.581031 — neuroscience — Posted on 2024-02-22
1224 CAMKV Kinase Signaling Is a Novel Therapeutic Avenue with Prognostic Relevance in Neuroblastoma
Yu, Y.; Zhao, Y.; Shi, Z.; Cheng, F.; Wang, L. L.; Choi, J. M.; Li, K.; Silverman, D.; Qi, D.; Wang, J.; Agarwal, S.; Rood, B.; Dome, J. S.; Fabbri, M.; Yi, J. S.; Wu, E.; Jung, S. Y.; Zhang, C.; Yang, J.
10.1101/2024.02.19.581040 — cancer biology — Posted on 2024-02-22
1227 Antibody-drug conjugates targeting EGFR ligand Epiregulin inhibit colorectal tumor growth irrespective of RAS mutational status
Jacob, J.; Anami, Y.; High, P.; Liang, Z.; Subramanian, S.; Ghosh, S. C.; AghaAmiri, S.; Guernsey, C.; Tran, H.; Liu, Q. J.; Rowe, J. H.; Azhdarinia, A.; Tsuchikama, K.; Carmon, K. S.
10.1101/2024.02.20.581056 — cancer biology — Posted on 2024-02-22
1228 Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch
Hicks, C. W.; Rahman, S.; Gloor, S. L.; Fields, J. K.; Husby, N. L.; Vaidya, A.; Maier, K. E.; Morgan, M.; Keogh, M.-C.; Wolberger, C.
10.1101/2024.02.22.581437 — biophysics — Posted on 2024-02-22
1229 After wounding, a G-protein coupled receptor promotes the restoration of tension in epithelial cells
Han, I.; Hua, J.; White, J. S.; O'Connor, J. T.; Nassar, L. S.; Tro, K. J.; Page-McCaw, A.; Hutson, M. S.
10.1101/2023.05.31.543122 — biophysics — Posted on 2024-02-22
1232 Centriolar satellites are sites of translation of centrosomal and ciliary proteins
Pachinger, C.; Dobbelaere, J.; Rumpf-Kienzl, C.; Raina, S.; Garcia-Baucells, J.; Sarantseva, M.; Brauneis, A.; Dammermann, A.
10.1101/2024.02.22.581531 — cell biology — Posted on 2024-02-22
1233 Septin-associated PIPKIγ splice variants drive centralspindlin association with the midbody via PI(4,5)P2
Russo, G.; Hümpfer, N.; Jaensch, N.; Restel, S.; Schmied, C.; Heyd, F.; Lehmann, M.; Haucke, V.; Ewers, H.; Krauss, M.
10.1101/2024.02.22.581562 — cell biology — Posted on 2024-02-22
1236 Sniffing is initiated by the actions of dopamine on ventral striatum neurons
Johnson, N. L.; Cotelo-Larrea, A.; Stetzik, L. A.; Akkaya, U. M.; Varga, A. G.; Ma, M.; Wesson, D. W.
10.1101/2024.02.19.581052 — neuroscience — Posted on 2024-02-22
1237 Confounding factors in targeted degradation of short-lived proteins
Vetma, V.; Perez, L. C.; Elias, J.; Stingu, A.; Kombara, A.; Gmaschitz, T.; Braun, N.; Ciftci, T.; Dahmann, G.; Diers, E.; Gerstberger, T.; Greb, P.; Kidd, G.; Kofink, C.; Puoti, I.; Spiteri, V.; Trainor, N.; Westermaier, Y.; Whitworth, C.; Ciulli, A.; Farnaby, W.; McAulay, K.; Frost, A. B.; Chessum, N.; Koegl, M.
10.1101/2024.02.19.581012 — cancer biology — Posted on 2024-02-22
1238 Overcoming brain-derived therapeutic resistance in HER2+ breast cancer brain metastasis
Ippolitov, D.; Lin, Y.-H.; Spence, J.; Glogowska, A.; Thanasupawat, T.; Beiko, J.; Del Bigio, M. R.; Xu, X.; Wang, A.; Calvo, R.; Kapoor, A.; Marugan, J. J.; Henderson, M. J.; Klonisch, T.; Hombach-Klonisch, S.
10.1101/2024.02.19.581073 — cancer biology — Posted on 2024-02-22
1239 Heat Stable and Intrinsically Sterile Liquid Protein Formulations
Lawanprasert, A.; Pimcharoen, S.; Singh, H.; Vargas, M. G.; Dewan, A.; Kirimanjeswara, G. S.; Medina, S.
10.1101/2024.02.19.581015 — biophysics — Posted on 2024-02-22
1242 A biodegradable microgrooved and tissue mechanocompatible citrate-based scaffold improves bladder tissue regeneration
Goedegebuure, M.; Bury, M.; Wang, X.; San Felice, P.; Cammarata, F.; Wang, L.; Sharma, T.; Rajinikanth, N.; Karra, V.; Siddha, V.; Sharma, A.; Ameer, G.
10.1101/2024.02.15.580554 — bioengineering — Posted on 2024-02-22
1246 α-catenin middle- and actin-binding domain unfolding mutants differentially impact epithelial strength and sheet migration
Quinn, J. M.; Wang, Y.; Wood, M. N.; Flozak, A. S.; Le, P. M.; Yemelyanov, A.; Oakes, P. W.; Gottardi, C. J.
10.1101/2023.02.01.526618 — cell biology — Posted on 2024-02-22
1247 The GPI sidechain of Toxoplasma gondii prevents parasite pathogenesis
Alvarez, J. A.; Gas-Pascual, E.; Malhi, S.; Njume, F. N.; Sanchez-Arcila, J. C.; van der Wel, H.; Zhao, Y.; Ceron, G.; Posada, J.; Souza, S. P.; Yap, G. S.; West, C.; Jensen, K. D. C.
10.1101/2024.02.21.581431 — microbiology — Posted on 2024-02-22
1249 Breathwork-Induced Psychedelic Experiences Modulate Neural Dynamics
Lewis-Healey, E.; Tagliazucchi, E.; Canales-Johnson, A.; Bekinschtein, T.
10.1101/2024.02.19.580985 — neuroscience — Posted on 2024-02-22
1250 Bayesian Workflow for Generative Modeling in Computational Psychiatry
Hess, A. J.; Iglesias, S.; Koechli, L.; Marino, S.; Mueller-Schrader, M.; Rigoux, L.; Mathys, C.; Harrison, O. K.; Heinzle, J.; Fraessle, S.; Stephan, K. E.
10.1101/2024.02.19.581001 — neuroscience — Posted on 2024-02-22
1256 Aerobic exercise promotes PDAC vascular normalization through S1PR1 signaling in tumor endothelial cells
Ballaro, R.; Pareek, S.; Lee, J.; Patel, H.; Tirumala, P.; Liu, G.; Hayek, K.; Savage, H.; Guerrouahen, B.; Ngo-Huang, A.; Parker, N.; Katz, M. H.; Petzel, M.; McAllister, F.; Wright, R.; Tan, L.; Lorenzi, P. L.; Schadler, K.
10.1101/2024.02.14.580332 — cancer biology — Posted on 2024-02-22
1258 Integrating population-level and cell-based signatures for drug repositioning
He, C.; Xu, Y.; Zhou, Y.; Fan, J.; Cheng, C.; Meng, R.; Gamazon, E. R.; Zhou, D.
10.1101/2023.10.25.564079 — bioinformatics — Posted on 2024-02-22
1260 Regional Centromere Configuration in the Fungal Pathogens of Pneumocystis Genus
Cisse, O. H.; Curran, S.; Folco, H. D.; Liu, Y.; Bishop, L.; Wang, H.; Fischer, E. R.; Davis, A. S.; Combs, C.; Dekker, J. P.; Grewal, S.; Cushion, M.; Ma, L.; Kovacs, J. A.
10.1101/2023.05.12.540427 — genomics — Posted on 2024-02-22
1263 Lineage-tracing of Acta2+ cells in aged mice during lung fibrosis formation and resolution supports the lipofibroblasts to myofibroblast reversible switch
Lingampally, A.; Truchi, M.; Mauduit, O.; Delcroix, V.; Hadzic, S.; Koepke, J.; Vazquez-Armendariz, A.-I.; Herold, S.; Samakovlis, C.; Makarenkova, H.; El Agha, E.; Chen, C.; Mari, B.; Bellusci, S.
10.1101/2024.02.19.580952 — pathology — Posted on 2024-02-22
1264 Unveiling the signaling network of FLT3-ITD AML improves drug sensitivity prediction
Latini, S.; Venafra, V.; Massacci, G.; Bica, V.; Graziosi, S.; Pugliese, G. M.; Iannuccelli, M.; Frioni, F.; Minnella, G.; Marra, J. D.; Chiusolo, P.; Pepe, G.; Helmer-Citterich, M.; Mougiakakos, D.; Boettcher, M.; Fischer, T.; Perfetto, L.; Sacco, F.
10.1101/2023.06.22.546072 — cancer biology — Posted on 2024-02-22
1267 Generalizable Neural Models of Emotional Engagement and Disengagement
Nanni Zepeda, M.; Evans, T.; Jagger-Rickels, A.; Raz, G.; Hendler, T.; Fan, Y.; Grimm, S.; Walter, M.; Esterman, M.; Zuberer, A.
10.1101/2024.02.15.579332 — neuroscience — Posted on 2024-02-22
1268 Diaminopurine in Nonenzymatic RNA Template Copying
Jia, X.; Fang, Z.; Kim, S. C.; Ding, D.; Zhou, L.; Szostak, J. W.
10.1101/2024.02.20.581310 — biochemistry — Posted on 2024-02-22
1271 UPP affects chloroplast development by interfering with chloroplast proteostasis
Scherer, V.; Bellin, L.; Schwenkert, S.; Lehmann, M.; Rinne, J.; Witte, C.-P.; Jahnke, K.; Richter, A. S.; Pruss, T.; Lau, A. S.; Waller, L.; Stein, S.; Leister, D.; Moehlmann, T.
10.1101/2023.08.28.555145 — molecular biology — Posted on 2024-02-22
1273 Convergent evolution of plant prickles is drivenby repeated gene co-option over deep time
Satterlee, J. W.; Alonso, D.; Gramazio, P.; Jenike, K. M.; He, J.; Arrones, A.; Villanueva, G.; Plazas, M.; Ramakrishnan, S.; Benoit, M.; Gentile, I.; Hendelman, A.; Shohat, H.; Fitzgerald, B.; Robitaille, G. M.; Green, Y.; Swartwood, K.; Passalacqua, M. J.; Gagnon, E.; Hilgenhof, R.; Huggins, T. D.; Eizenga, G. C.; Gur, A.; Rutten, T.; Stein, N.; Yao, S.; Bellot, C.; Bendahmane, M.; Frary, A.; Knapp, S.; Sarkinen, T.; Gillis, J.; Van Eck, J.; Schatz, M. C.; Eshed, Y.; Prohens, J.; Vilanova, S.; Lippman, Z. B.
10.1101/2024.02.21.581474 — evolutionary biology — Posted on 2024-02-22
1274 Generation of diversity in the blue cheese mold Penicillium roqueforti and identification of pleiotropic QTL for key cheese-making phenotypes
Caron, T.; Crequer, E.; Le Piver, M.; Le Prieur, S.; Sammy, B.; Snirc, A.; Cueff, G.; Roueyre, D.; Place, M.; Chassard, C.; Simon, A.; Rodriguez de la Vega, R. C.; Coton, M.; Coton, E.; Foulongne-Oriol, M.; Branca, A.; Giraud, T.
10.1101/2024.02.22.581506 — evolutionary biology — Posted on 2024-02-22
1275 The 2023 wildfire season in Quebec: an overview of extreme conditions, impacts, lessons learned and considerations for the future.
Boulanger, Y.; Arseneault, D.; Belisle, A.-C.; Bergeron, Y.; Boucher, J.; Boucher, Y.; Danneyrolles, V.; Erni, S.; Gachon, P.; Girardin, M.; Grant, E.; Grondin, P.; Jette, J.-P.; Labadie, G.; Leblond, M.; Leduc, A.; Puigdevall, J. P.; St-Laurent, M.-H.; Tremblay, J.; Waldron, K.
10.1101/2024.02.20.581257 — ecology — Posted on 2024-02-22
1278 Macropinocytosis mediates resistance to loss of glutamine transport in triple-negative breast cancer
Wahi, K.; Freidman, N.; Wang, Q.; Devadason, M.; Quek, L.-E.; Pang, A.; Lloyd, L.; Larance, M.; Zanini, F.; Harvey, K.; O'Toole, S.; Guan, Y. F.; Holst, J.
10.1101/2024.02.21.581493 — cancer biology — Posted on 2024-02-22
1283 Purging viral latency by a bifunctional HSV-vectored therapeutic vaccine in chronically SIV-infected macaques
Wen, Z.; Li, P.; Yuan, Y.; Wang, C.; Li, M.; Wang, H.; Shi, M.; He, Y.; Cui, M.; Chen, L.; Sun, C.
10.1101/2024.02.20.581122 — microbiology — Posted on 2024-02-22
1284 Contribution of Urea to Nitrite Production in Southern Ocean Waters with Contrasting Nitrifying Communities
Hollibaugh, J. T.; Okotie-Oyekan, A.; Damashek, J.; Ducklow, H.; Popp, B.; Wallsgrove, N.; Allen, T.
10.1101/2024.02.20.581251 — microbiology — Posted on 2024-02-22
1285 The GPI sidechain of Toxoplasma gondii prevents parasite pathogenesis
Alvarez, J. A.; Gas-Pascual, E.; Malhi, S.; Njume, F. N.; Sanchez-Arcila, J. C.; van der Wel, H.; Zhao, Y.; Ceron, G.; Posada, J.; Souza, S. P.; Yap, G. S.; West, C.; Jensen, K. D. C.
10.1101/2024.02.21.581431 — microbiology — Posted on 2024-02-22
1286 Maturing neutrophils of lower density associate with thrombocytopenia in Puumala orthohantavirus-caused hemorrhagic fever with renal syndrome
Cabrera, L. E.; Tietavainen, J.; Jokiranta, S. T.; Makela, S. M.; Vaheri, A.; Mustonen, J.; Vapalahti, O.; Kanerva, M.; Strandin, T.
10.1101/2024.02.19.580937 — immunology — Posted on 2024-02-22
1287 Comparative analyses of adsorbed circulating proteins in the PMMA and PES hemodiafilters in patients on predilution online hemodiafiltration
Islam, M. S.; Ema, S.; Nabi, M. M.; Rahman, M. M.; Waliullah, A. S. M.; Yan, J.; Ferdous, R.; Sakamoto, T.; Takahashi, Y.; Kato, A.; Kahyo, T.; Sato, T.; Setou, M.
10.1101/2024.02.16.580786 — pathology — Posted on 2024-02-22
1289 Exploiting cryo-EM structures of actomyosin-5a to reveal the physical properties of its lever
Gravett, M. S. C.; Klebl, D. P.; Harlen, O. G.; Read, D. J.; Harris, S. A.; Muench, S. P.; Peckham, M.
10.1101/2023.03.19.533260 — biophysics — Posted on 2024-02-22
1290 Interactive visualisation of raw nanopore signal data with Squigualiser
Samarakoon, H.; Liyanage, K.; Ferguson, J.; Parameswaran, S.; Gamaarachchi, H.; Deveson, I.
10.1101/2024.02.19.581111 — bioinformatics — Posted on 2024-02-22
1291 Pre-mRNA fate decision safeguards the fidelity of the inflammatory response
Bestehorn, A. M.; Fesselet, J. A. M.; Didusch, S.; Zeiler, C.; Doppelmayer, K.; Borroni, M.; Le Heron, A.; Pfanzagl, V.; Chen, W.; Scinicariello, S.; Baccarini, M.; Versteeg, G. A.; Hartl, M.; Kovarik, P.
10.1101/2023.11.30.569392 — molecular biology — Posted on 2024-02-22
1293 Beyond the Colony-Forming-Unit: Rapid Bacterial Evaluation in Osteomyelitis
Sun, Q.; Huynh, K.; Muratovic, D.; Gunn, N. J.; Zelmer, A. R.; Solomon, L. B.; Atkins, G. J.; Yang, D.
10.1101/2023.11.21.568051 — microbiology — Posted on 2024-02-22
1294 Discovery and Repurposing of Pharmaceutical Agents as Antifungals: In vivo activity against Coccidioides
Mead, H.; Valentine, M.; Thompson, G. R.; Yin, H.; Keim, P.; Engelthaler, D. M.; Barker, B. M.
10.1101/2024.02.21.581462 — microbiology — Posted on 2024-02-22
1297 The Architecture of Sponge Choanocyte Chambers Maximizes Mechanical Pumping Efficiency
Ogawa, T.; Koyama, S.; Omori, T.; Kikuchi, K.; de Maleprade, H.; Goldstein, R. E.; Ishikawa, T.
10.1101/2024.02.22.581376 — biophysics — Posted on 2024-02-22
1299 The CryoEM structure of human serum albumin in complex with ligands
Catalano, C.; Lucier, K. W.; To, D.; Senko, S.; Tran, N. L.; Farwell, A. C.; Silva, S. M.; Dip, P. V.; Poweleit, N.; Scapin, G.
10.1101/2024.02.21.581427 — biochemistry — Posted on 2024-02-22
1300 An Engineered IGF2 Mutant for Lysosomal Targeting Chimeras Development and Membrane Proteins Degradation
Pan, Y.; Xiang, Q.; Deng, K.; Anwar, M.; Wang, L.; Wang, Y.; Liang, Q.; Shen, L.; Yang, J.; Shen, W.
10.1101/2024.02.20.581320 — biochemistry — Posted on 2024-02-22
1302 Augmentation of DNA exonuclease TREX1 in macrophages as a therapy for cardiac ischemic injury
Ibrahim, A. G.-E.; Ciullo, A.; Miyamoto, K.; Liao, K.; Jones, X.; Yamaguchi, S.; Li, C.; Rannou, A.; Nawaz, A.; Morris, A. A.; Tsi, K.; Marban, C. H.; Lee, J.; Manriquez, N.; Hong, Y.; Kumar, A. N.; Dawkins, J. F.; Rogers, R. G.; Marban, E.
10.1101/2024.02.20.581294 — molecular biology — Posted on 2024-02-22
1303 A modular toolkit for environmental Rhodococcus, Gordonia, and Nocardia enables complex metabolic manipulation.
Jansen, Z.; Alameri, A.; Wei, Q.; Kulhanek, D. L.; Gilmour, A. R.; Halper, S.; Schwalm, N. D.; Thyer, R.
10.1101/2024.02.21.581484 — microbiology — Posted on 2024-02-22
1304 DCAF16-Based Covalent Handle for the Rational Design of Monovalent Degraders
Lim, M.; Do Cong, T.; Orr, L. M.; Toriki, E. S.; Kile, A. C.; Papatzimas, J. W.; Lee, E.; Nomura, D. K.
10.1101/2024.02.20.580683 — biochemistry — Posted on 2024-02-22
1305 Diaminopurine in Nonenzymatic RNA Template Copying
Jia, X.; Fang, Z.; Kim, S. C.; Ding, D.; Zhou, L.; Szostak, J. W.
10.1101/2024.02.20.581310 — biochemistry — Posted on 2024-02-22
1306 Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus
Fernandez, I.; Saunders, N.; Duquerroy, S.; Bolland, W. H.; Arbabian, A.; Baquero, E.; Blanc, C.; Lafaye, P.; Haouz, A.; Buchrieser, J.; Schwartz, O.; Rey, F. A.
10.1101/2024.02.21.581378 — biochemistry — Posted on 2024-02-22
1308 Thermostable in vitro transcription-translation for enzyme screening in microdroplets
Ribeiro, A.-L.; Perez-Arnaiz, P.; Sanchez-Costa, M.; Perez, L.; Almendros, M.; van Vliet, L.; Gielen, F.; Lim, J.; Charnock, S.; Hollfelder, F.; Gonzalez-Pastor, J. E.; Berenguer, J.; Hidalgo, A.
10.1101/2024.02.22.580490 — microbiology — Posted on 2024-02-22
1309 Rapid generation and screening of transgenic black soldier fly (Hermetia illucens)
Pfitzner, C.; Tepper, K.; Kumar, S.; Retief, C.; McNab, J.; Harrell, R. A.; Maselko, M.
10.1101/2024.02.21.581498 — synthetic biology — Posted on 2024-02-22
1311 Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation
Shinoda, S.; Sakai, Y.; Matsui, T.; Uematsu, M.; Koyama-Honda, I.; Sakamaki, J.-i.; Yamamoto, H.; Mizushima, N.
10.1101/2023.09.11.557142 — cell biology — Posted on 2024-02-22
1312 Interaction of GAT1 with sodium ions: from efficient recruitment to stabilisation of substrate and conformation
Lazzarin, E.; Gradisch, R.; Skopec, S. M.; Alves da Silva, L.; Sebastianelli-Schoditsch, C.; Szollosi, D.; Maier, J.; Sucic, S.; Roblek, M.; Kanner, B.; Sitte, H. H.; Stockner, T.
10.1101/2023.10.10.561652 — molecular biology — Posted on 2024-02-22
1314 Systematic Analysis of Immune Changes after B-cell Depletion in Autoimmune Multiple Sclerosis
Wei, J.; Moon, J.; Yasumizu, Y.; Zhang, L.; Radassi, K.; Buitrago-Pocasangre, N.; Deerhake, M. E.; Strauli, N.; Chan, A.; Herman, A.; Pedotti, R.; Raposo, C.; Yim, I.; Pappalardo, J.; Longbrake, E. E.; Sumida, T. S.; Axisa, P.-P.; Hafler, D. A.
10.1101/2024.02.07.576204 — immunology — Posted on 2024-02-22
1316 Exposure to bilingual or monolingual maternal speech during pregnancy affects the neurophysiological encoding of speech sounds in neonates differently
Arenillas-Alcon, S.; Gorina-Careta, N.; Puertollano, M.; Mondejar-Segovia, A.; Ijjou-Kadiri, S.; Costa-Faidella, J.; Gomez-Roig, M. D.; Escera, C.
10.1101/2024.02.21.579933 — neuroscience — Posted on 2024-02-22
1317 Behavioral fingerprinting of the naked mole-rat uncovers signatures of eusociality and social touch
Schwark, R.; Ogundare, S.; Weinreb, C.; Sheng, P.; Foster, W.; Toussaint, A.; Chang, P.; Tsai, Y.-Y.; Comfere, M.; Arnold, A.; Guadagnino, A.; McCloskey, D.; Schaffer, E.; Rajan, K.; Datta, S. R.; Abdus-Saboor, I.
10.1101/2024.02.21.581483 — neuroscience — Posted on 2024-02-22
1318 Female mice lacking GluA3 show early onset of hearing loss, synaptopathy, and afferent swellings in ambient sound levels
Pal, I.; Bhattacharyya, A.; V-Ghaffari, B.; Williams, E. D.; Xiao, M.; Rutherford, M. A.; Rubio, M. E.
10.1101/2024.02.21.581467 — neuroscience — Posted on 2024-02-22
1319 Fetal brain response to maternal inflammation requires microglia
Ostrem, B.; Dominguez Iturza, N.; Stogsdill, J.; Faits, T.; Kim, K.; Levin, J. Z.; Arlotta, P.
10.1101/2024.02.21.581282 — neuroscience — Posted on 2024-02-22
1320 Incomplete remyelination via endogenous or therapeutically enhanced oligodendrogenesis is sufficient to recover visual cortical function
Nunes, G. D.-F.; Osso, L. A.; Haynes, J. A.; Morris, A. M.; Conant, L.; Stockton, M. E.; Thornton, M. A.; Vivian, J. A.; Gandhi, R.; Denman, D. J.; Hughes, E. G.
10.1101/2024.02.21.581491 — neuroscience — Posted on 2024-02-22
1321 Unveiling Inter-Embryo Variability in Spindle Length over time: towards Quantitative Phenotype Analysis.
Le Cunff, Y.; Chesneau, L.; Pastezeur, S.; Pinson, X.; Soler, N.; Fairbrass, D.; Mercat, B.; Rodriguez Garcia, R.; Alayan, Z.; Abdouni, A.; de Neidhardt, G.; Costes, V.; Anjubault, M.; Bouvrais, H.; Heligon, C.; Pecreaux, J.
10.1101/2023.05.01.538870 — bioinformatics — Posted on 2024-02-21
1322 Pathological mechanisms and candidate therapeutic approaches in the hearing loss of mice carrying human MIR96 mutations
Lewis, M. A.; Lachgar-Ruiz, M.; Di Domenico, F.; Duddy, G.; Chen, J.; Fernandez, S.; Morin, M.; Williams, G.; Moreno-Pelayo, M. A.; Steel, K. P.
10.1101/2024.02.20.581141 — genetics — Posted on 2024-02-21
1323 The modification landscape of P. aeruginosa tRNAs
Mandler, M. D.; Maligireddy, S. S.; Guinlet, W. M.; Fitzsimmons, C. M.; McDonald, K. S.; Warrel, D. L.; Batista, P. J.
10.1101/2024.02.21.581370 — microbiology — Posted on 2024-02-21
1325 Cone-opponent ganglion cells in the primate fovea tuned to non-cardinal color directions
Godat, T.; Kohout, K.; Parkins, K.; Yang, Q.; McGregor, J. E.; Merigan, W. H.; Williams, D. R.; Patterson, S. S.
10.1101/2023.09.15.557995 — neuroscience — Posted on 2024-02-21
1334 Membrane contact sites regulate vacuolar fission via sphingolipid metabolism
Hanaoka, K.; Nishikawa, K.; Ikeda, A.; Schlarmann, P.; Sasaki, S.; Yamashita, S.; Nakaji, A.; Fujii, S.; Funato, K.
10.1101/2023.06.21.546015 — cell biology — Posted on 2024-02-21
1335 Habit learning shapes activity dynamics in the central nucleus of the amygdala
Amaya, K. A.; Carmichael, J. E.; Townsend, E. S.; Palmer, J. A.; Stott, J. J.; Smith, K. S.
10.1101/2024.02.20.580730 — neuroscience — Posted on 2024-02-21
1336 Cas9 nickase-mediated contraction of CAG/CTG repeatsat multiple disease loci
Murillo, A.; Alpaugh, M.; Larin, M.; Randall, E. L.; Heraty, L.; Durairaj, R. R.; Aston, A. N.; Taylor, A. S.; Monteys, A. M.; Stoberl, N.; Heuchan, A. E.; Aeschlimann, P.; Bhattacharyya, S.; Allen, N. D.; Puymirat, J.; Davidson, B. L.; Chicchetti, F.; Lelos, M.; Dion, V.
10.1101/2024.02.19.580669 — neuroscience — Posted on 2024-02-21
1340 Tertiary lymphoid structure-related immune infiltrates in NSCLC tumor lesions correlate with low tumor-reactivity of TIL products
Castenmiller, S. M.; Kanagasabesan, N.; Guislain, A.; Nicolet, B.; van Loenen, M.; Monkhorst, K.; Veenhof, A.; Smit, E.; Hartemink, K.; Haanen, J.; de Groot, R.; Wolkers, M.
10.1101/2024.02.19.580998 — immunology — Posted on 2024-02-21
1342 Drosophila epidermal cells are intrinsically mechanosensitive and modulate nociceptive behavioral outputs
Yoshino, J.; Mali, S.; Williams, C.; Morita, T.; Emerson, C.; Arp, C.; Miller, S.; Yin, C.; The, L.; Chikaya, H.; Motoyoshi, M.; Ishii, K.; Emoto, K.; Bautista, D. M.; Parrish, J. Z.
10.1101/2022.10.07.511265 — neuroscience — Posted on 2024-02-21
1344 Development of a Marmoset Apparatus for Automated Pulling (MarmoAAP) to Study Cooperative Behaviors
Meisner, O. C.; Fagan, N. A.; Greenwood, J.; Shi, W.; Jadi, M.; Nandy, A. S.; Chang, S. W. C.
10.1101/2024.02.16.579531 — neuroscience — Posted on 2024-02-21
1345 Plastic vasomotion entrainment
Sasaki, D.; Imai, K.; Ikoma, Y.; Matsui, K.
10.1101/2023.11.20.567853 — neuroscience — Posted on 2024-02-21
1346 Prevalence and genotypes of Chlamydia psittaci in pet birds of Hong Kong
Ko, J. C. K.; Choi, Y. W. Y.; Poon, E. S. K.; Wyre, N.; Go, J. L. L.; Poon, L. L. M.; Sin, S. Y. W.
10.1101/2024.02.19.581005 — zoology — Posted on 2024-02-21
1350 FLOWERING LOCUS C integrates carbon and nitrogen signaling for the proper timing of flowering in Arabidopsis
Gramma, V.; Olas, J. J.; Zacharaki, V.; Ponnu, J.; Luzarowska, U.; Musialak-Lange, M.; Wahl, V.
10.1101/2024.02.15.580522 — plant biology — Posted on 2024-02-21
1351 The DC1 domain protein Vacuoleless Gametophytes regulates stamen development in Arabidopsis
Amigo, N. L.; Arias, L. A.; Marchetti, M. F.; D'Ippolito, S.; Frik, J.; Lombardo, M. C.; Terrile, M. C.; Casalongue, C. A.; Pagnussat, G. C.; Fiol, D. F.
10.1101/2024.02.19.580957 — plant biology — Posted on 2024-02-21
1352 A circadian transcriptional sub-network and EARLY FLOWERING 3 control timing of senescence and grain nutrition in bread wheat
Buckley, C. R.; Boyte, J. M.; Albiston, R. L.; Hyles, J.; Beasley, J. T.; Johnson, A. A.; Trevaskis, B.; Fournier-Level, A.; Haydon, M. J.
10.1101/2024.02.19.580927 — plant biology — Posted on 2024-02-21
1353 Elucidating molecular responses to spittlebug attack in Paspalum regnellii
Begnami, I. S.; Aono, A. H.; Graciano, D. S.; Carmello-Guerreiro, S. M.; Ferreira, R. C. U.; Malago, W.; Gusmao, M. R.; Souza, A. P.; Vigna, B. B. Z.
10.1101/2023.08.29.555367 — plant biology — Posted on 2024-02-21
1354 Sucrose-responsive osmoregulation of plant cell size by a long non-coding RNA
Hajny, J.; Travnickova, T.; Rony, R. M. I. K.; Sacharowski, S.; Krzyszton, M.; Zalabak, D.; Hardtke, C.; Pecinka, A.; Swiezewski, S.; Van Norman, J. M.; Novak, O.
10.1101/2024.02.19.581113 — plant biology — Posted on 2024-02-21
1358 Development of an orthotopic medulloblastoma zebrafish model for rapid drug testing.
van Bree, N. F. H. N.; Oppelt, A.-S.; Lindstrom, S.; Zhou, L.; Boutin, L.; Johnsen, J. I.; Brautigam, L.; Wilhelm, M. T.
10.1101/2024.02.21.578208 — cancer biology — Posted on 2024-02-21
1359 The SUMOylation inhibitor TAK-981 (Subasumstat) triggers IFN-I-dependent activation of Natural Killer cells against Acute Myeloid Leukemias.
Hallal, R.; De Toledo, M.; Tempe, D.; Zemiti, S.; Coenon, L.; Gitenay, D.; George, S.; Bonnet, S.; Gabellier, L.; Cartron, G.; Pelegrin, M.; Villalba, M.; Bossis, G.
10.1101/2024.02.19.580882 — cancer biology — Posted on 2024-02-21
1362 Personalized composite scaffolds for accelerated cell- and growth factor-free craniofacial bone regeneration
Kim, M.; Collins, C.; Liu, Y.; Tsal, H.-M.; Ahn, Y.; Wang, X.; Song, J.; Duan, C.; Sun, C.; Yi, Z.; He, T.-C.; Reid, R.; Ameer, G.
10.1101/2024.02.18.580898 — bioengineering — Posted on 2024-02-21
1364 The genomic and cultural diversity of the Inka Qhapaq hucha ceremony in Chile and Argentina
Castro, C. d. l. F.; Cortes, C.; Raghavan, M.; Castillo, D.; Castro, M.; Verdugo, R.; Moraga, M.
10.1101/2024.02.19.581063 — genomics — Posted on 2024-02-21
1365 Evolutionary genomics of the emergence of brown algae as key components of coastal ecosystems
Denoeud, F.; Godfroy, O.; Cruaud, C.; Heesch, S.; Nehr, Z.; Tadrent, N.; Couloux, A.; Brillet-Gueguen, L.; Delage, L.; Mckeown, D.; Motomura, T.; Sussfeld, D.; Fan, X.; Mazeas, L.; Terrapon, N.; Barrera-Redondo, J.; Petroll, R.; Reynes, L.; Choi, S.-W.; Jo, J.; Uthanumallian, K.; Bogaert, K.; Duc, C.; Ratchinski, P.; Lipinska, A.; Noel, B.; Murphy, E. A.; Lohr, M.; Khatei, A.; Hamon-Giraud, P.; Vieira, C.; Akerfors, S. S.; Akita, S.; Avia, K.; Badis, Y.; Barbeyron, T.; Belcour, A.; Berrabah, W.; Blanquart, S.; Bouguerba, A.; Bringloe, T. T.; Cattolico, R. A.; Cormier, A.; Cruz de Carvalho, M.
10.1101/2024.02.19.579948 — genomics — Posted on 2024-02-21
1366 Single-cell multimodal profiling of monocytes reveals diverse phenotypes and alterations linked to cardiovascular disease risks
Bashore, A. C.; Xue, C.; Kim, E.; Yan, H.; Zhu, L. Y.; Kissner, M.; Ross, L.; Zhang, H.; Li, M.; Reilly, M.; Pan, H.
10.1101/2024.02.18.580913 — genomics — Posted on 2024-02-21
1367 Gene expression signatures of response to fluoxetine treatment: systematic review and meta-analyses
Cooper, D. G.; Cowden, J. P.; Stanley, P. A.; Karbowski, J. T.; Gaertig, V. S.; Lukan, C. J.; Vo, P. M.; Worthington, A. D.; Class, C. A.
10.1101/2024.02.19.581045 — genomics — Posted on 2024-02-21
1368 Genetic Modulation of Protein Expression in Rat Brain
Li, L.; Wu, Z.; Guarracino, A.; Villani, F.; Kong, D.; Mancieri, A.; Zhang, A.; Saba, L. M.; Chen, H.; Brozka, H.; Vales, K.; Senko, A. N.; Kempermann, G.; Stuchlik, A.; Pravenec, M.; Prins, P.; Peng, J.; Williams, R.; Wang, X.
10.1101/2024.02.17.580840 — genetics — Posted on 2024-02-21
1369 Cephalopod Sex Determination and its AncientEvolutionary Origin Revealed by Chromosome-levelAssembly of the California two-spot Octopus
Coffing, G. C.; Tittes, S.; Small, S. T.; Songco-Casey, J. O.; Piscopo, D. M.; Pungor, J. R.; Miller, A. C.; Niell, C.; Kern, A. D.
10.1101/2024.02.21.581452 — evolutionary biology — Posted on 2024-02-21
1370 Leveraging the Red List of Ecosystems for national action on coral reefs through the Kunming-Montreal Global Biodiversity Framework
Gudka, M.; Obura, D.; Treml, E.; Samoilys, M.; Aboud, S. A.; Osuka, K.; Mbugua, J.; Mwaura, J.; Karisa, J.; Knoester, E.; Musila, P.; Omar, M.; Nicholson, E.
10.1101/2024.02.18.580850 — ecology — Posted on 2024-02-21
1373 Transinfection of Wolbachia wAlbB into Culex quinquefasciatus mosquitoes does not alter vector competence for Hawaiian avian malaria (Plasmodium relictum GRW4)
Kilpatrick, A. M.; Seidl, C. M.; Ipsaro, I. J.; Garrison, C. E.; Fabbri, G.; Howell, P. I.; McGowan, A. G.; White, B. J.; Mitchell, S. N.
10.1101/2024.02.16.580617 — ecology — Posted on 2024-02-21
1374 The moon's influence on the activity of tropical forest mammals
Bischof, R.; Vallejo Vargas, A. F.; Semper-Pascual, A.; Schowanek, S.; Beaudrot, L.; Turek, D.; Jansen, P. A.; Rovero, F.; Johnson, S. E.; Lima, M. G. M.; Santos, F.; Uzabaho, E.; Espinosa, S.; Ahumada, J. A.; Bitariho, R.; Salvador, J.; Mugerwa, B.; Sainge, M. N.; Sheil, D.
10.1101/2024.02.20.581159 — ecology — Posted on 2024-02-21
1375 Transcriptional profiling sheds light on the fibrotic aspects of idiopathic subglottic tracheal stenosis
Direder, M.; Laggner, M.; Copic, D.; Klas, K.; Bormann, D.; Schweiger, T.; Hoetzenecker, K.; Aigner, C.; Ankersmit, H. J.; Mildner, M.
10.1101/2024.02.19.580975 — developmental biology — Posted on 2024-02-21
1376 Hepatocyte differentiation requires anisotropic expansion of bile canaliculi
Belicova, L.; Bebelman, M.; Gralinska, E.; Jumel, T.; Lahree, A.; Shevchenko, A.; Zatsepin, T.; Kalaidzidis, Y.; Vingron, M.; Zerial, M.
10.1101/2024.02.19.581065 — developmental biology — Posted on 2024-02-21
1378 Membrane Bound O-Acyltransferase 7 (MBOAT7) Shapes Lysosomal Lipid Homeostasis and Function to Control Alcohol-Associated Liver Injury
Varadharajan, V.; Ramachandiran, I.; Massey, W. J.; Jain, R.; Banerjee, R.; Horak, A. J.; McMullen, M. R.; Huang, E.; Bellar, A.; Lorkowski, S. W.; Gulshan, K.; Helsley, R. N.; James, I.; Pathak, V.; Dasarathy, J.; Welch, N.; Dasarathy, S.; Streem, D.; Reizes, O.; Allende, D. S.; Smith, J. D.; Simcox, J.; Nagy, L. E.; Brown, J. M.
10.1101/2023.09.26.559533 — molecular biology — Posted on 2024-02-21
1380 Lessons from twenty years of the life of commensal Escherichia coli populations in a human gut
Condamine, B.; Morel-Journel, T.; Tesson, F.; Magnan, M.; Bernheim, A.; Denamur, E.; Blanquart, F.; Clermont, O.
10.1101/2024.02.21.581337 — microbiology — Posted on 2024-02-21
1381 High phenotypic and genotypic plasticity among strains of the mushroom-forming fungus Schizophyllum commune
Marian, I. M.; Valdes, I. D.; Hayes, R. D.; LaButti, K.; Duffy, K.; Chovatia, M.; Johnson, J.; Ng, V.; Lugones, L. G.; Wosten, H. A. B.; Grigoriev, I. V.; Ohm, R. A.
10.1101/2024.02.21.581338 — microbiology — Posted on 2024-02-21
1384 NR4A3 deficiency ameliorates contact hypersensitivity and exacerbates psoriasis by regulating gene expression in dendritic cells
Katagiri, M.; Ito, N.; Nagata, K.; Nakano, S.; Minamikawa, N.; Yamashita, N.; Takahashi, M.; Kurihara, M.; Nagaoka, M.; Ando, M.; Ito, T.; Yashiro, T.; Yoshimura, A.; Nishiyama, C.
10.1101/2024.02.20.581116 — immunology — Posted on 2024-02-21
1386 Pathogenic tau induces an adaptive elevation in mRNA translation rate at early stages of disease
Zuniga, G.; Katsumura, S.; De Mange, J.; Ramirez, P.; Atrian, F.; Morita, M.; Frost, B.
10.1101/2024.02.19.581061 — neuroscience — Posted on 2024-02-21
1387 Polygenic Risk for Alcohol Use Disorder Affects Cellular Responses to Ethanol Exposure in a Human Microglial Cell Model
Li, X.; Liu, J.; Boreland, A.; Kapadia, S.; Zhang, S.; Stillitano, A.; Abbo, Y.; Clark, L.; Lai, D.; Li, Y.; Barr, P.; Meyers, J.; Kamarajan, c.; Kuang, W.; Agrawal, A.; Slesinger, P.; Dick, D.; Salvatore, J.; Tischfield, J.; Duan, J.; Edenberg, H.; Kreimer, A.; Hart, R. P.; Pang, Z. P.
10.1101/2024.02.19.581066 — neuroscience — Posted on 2024-02-21
1390 Alveolar macrophages play a key role in tolerance to ozone
Smith, G.; Nalesnik, M.; Immormino, R.; Simon, J.; Harkema, J. R.; Mock, J. R.; Moran, T. P.; Kelada, S. N. P.
10.1101/2024.02.18.580749 — pharmacology and toxicology — Posted on 2024-02-21
1391 Molecular dynamics simulations reveal molecular mechanisms for the gain and loss of function effects of four SCN2A variants
Bhattarai, N.; Montanucci, L.; Brunger, T.; Palma, E. P.; Martin, W.; Smith, I. N.; Eng, C.; Cheng, F.; Helbig, I.; Moller, R.; Brunklaus, A.; Schorge, S.; Lal, D.
10.1101/2024.02.19.580930 — biophysics — Posted on 2024-02-21
1392 RUDEUS, a machine learning classification system to study DNA-Binding proteins
Medina-Ortiz, D.; Cabas-Mora, G.; Moya-Barria, I.; Soto-Garcia, N.; Uribe-Paredes, R.
10.1101/2024.02.19.580825 — bioinformatics — Posted on 2024-02-21
1395 New, biomechanically sound tendon tissue after injection of uncultured, autologous, adipose derived regenerative cells in partial Achilles tendon defects in rabbits
Schmitz, C.; Alt, C.; Wuerfel, T.; Milz, S.; Dinzey, J.; Hill, A.; Sikes, K. J.; Burton, L.; Easley, J.; Stewart, H. L.; Puttlitz, C.; Gadomski, B. C.; Labus, K.; Pearce, D. A.; Maffulli, N.; Alt, E. U.
10.1101/2024.02.18.580890 — bioengineering — Posted on 2024-02-21
1396 Functional avidity of anti-B7H3 CAR-T constructs predicts antigen density thresholds for triggering effector function
Barisa, M.; Zappa, E.; Muller, H.; Shah, R.; Buhl, J.; Draper, B.; Himsworth, C.; Bowers, C.; Munnings-Tomes, S.; Nicolaidou, M.; Morlando, S.; Birley, K.; Leboreiro-Babe, C.; Vitali, A.; Privitera, L.; O'Sullivan, K.; Greppi, A.; Buschhaus, M.; Barrera Roman, M.; de Blank, S.; van den Ham, F.; van 't Veld, B. R.; Ferry, G.; Donovan, L. K.; Chesler, L.; Molenaar, J. J.; Drost, J.; Rios, A. C.; Chester, K.; Wienke, J.; Anderson, J.
10.1101/2024.02.19.580939 — bioengineering — Posted on 2024-02-21
1397 A Model of Ethanol Self-Administration in Head-Fixed Mice
Ward, A. L.; Winston, K. T.; Buchmaier, S. A.; Clarke, R. E.; Bell, M. S.; Martino, M. R.; Vollmer, K. M.; Paniccia, J.; Doncheck, E. M.; Grant, R. I.; Otis, J. M.; Rinker, J. A.
10.1101/2024.02.17.580838 — animal behavior and cognition — Posted on 2024-02-21
1399 Genomic 8-oxoguanine modulates gene transcription independent of its repair by DNA glycosylases OGG1 and MUTYH
Obermann, T.; Sakshaug, T.; Kanagaraj, V. V.; Abentung, A.; Sarno, A.; Bjoras, M.; Scheffler, K.
10.1101/2024.02.20.581185 — genomics — Posted on 2024-02-21
1400 The ivory lncRNA regulates seasonal color patterns in buckeye butterflies
Fandino, R. A.; Brady, N. K.; Chatterjee, M.; McDonald, J. M. C.; Livraghi, L.; van der burg, K.; Mazo-Vargas, A.; Markenscoff-Papadimitriou, E.; Reed, R. D.
10.1101/2024.02.09.579733 — genetics — Posted on 2024-02-21
1401 Playing with the ploidy level enables to switch on and off the strict recombination control even in the vicinity of Brassica centromeres
Boideau, F.; Huteau, V.; Brunet, A.; Maillet, L.; Coriton, O.; Trotoux, G.; Lode-Taburel, M.; Deniot, G.; Eber, F.; Gilet, M.; Boutte, J.; Morice, J.; Falentin, C.; Martin, O.; Falque, M.; Chevre, A.-M.; Rousseau-Gueutin, M.
10.1101/2024.02.19.580878 — genetics — Posted on 2024-02-21
1405 Multilevel proteomic profiling of colorectal adenocarcinoma cell differentiation to characterize an intestinal epithelial model
Fekete, E. E.; Wang, A.; Creskey, M.; Cummings, S. E.; Lavoie, J. R.; Ning, Z.; Li, J.; Figeys, D.; Chen, R.; ZHANG, X.
10.1101/2024.02.19.581096 — systems biology — Posted on 2024-02-21
1406 Effect of alpha-tubulin acetylation on the doublet microtubule structure
Yang, S. K.; Kubo, S.; Black, C. S.; Peri, K.; Dai, D.; Legal, T.; Valente-Paterno, M.; Gaertig, J.; Bui, K. H.
10.1101/2023.09.21.558788 — cell biology — Posted on 2024-02-21
1407 Importance of environmental signals for proper cardiac morphological development in Atlantic salmon
Johansen, I. B.; Vindas, M. A.; Engdal, V. A.; Kavaliauskiene, S.; Folkedal, O.; Hoglund, E.; Moyano, M.; Overli, O.; Frisk, M.
10.1101/2024.02.19.580955 — physiology — Posted on 2024-02-21
1408 Oxygen carrying nanoemulsions and respiratory hyperoxia eliminate tumor hypoxia-induced suppression and improve cancer immunotherapy
Halpin-Veszeleiova, K.; Mallouh, M.; Apro, A.; Romero, N.; Bahr, C.; Shin, M.; Ward, K.; Rosenberg, L.; Sitkovsky, M.; Spiess, B.; Hatfield, S. M.
10.1101/2024.02.17.580835 — immunology — Posted on 2024-02-21
1411 Nerve injury downregulates δ-opioid and cannabinoid CB1 receptor genes through REST in primary sensory neurons
Subedi, A.; Tiwari, A.; Etemad, A. F.; Huang, Y.; Chatterjee, B.; McLeod, S. L.; Lu, Y.; Gonzalez, D.; Ghosh, K.; Singh, S. K.; Ruiz Echartea, M. E.; Grimm, S. L.; Coarfa, C.; Pan, H.-L.; Majumder, S.
10.1101/2024.02.17.579842 — neuroscience — Posted on 2024-02-21
1414 Unveiling neoadjuvant chemotherapy-induced immune landscape remodeling and metabolic reprogramming in lung adenocarcinoma by scRNA-sequencing
Huang, Y.; Cheng, L.; Bi, G.; Liang, J.; Li, M.; Zhang, H.; Shan, G.; Hu, Z.; Chen, Z.; Wu, G.; Lin, Z.; Jiang, W.; Wang, Q.; XI, J.; Zhan, C.; Yin, S.
10.1101/2024.02.18.580893 — cancer biology — Posted on 2024-02-21
1419 Enhanced Protein-Protein Interaction Discovery via AlphaFold-Multimer
Kim, A.-R.; Hu, Y.; Comjean, A.; Rodiger, J.; Mohr, S. E.; Perrimon, N.
10.1101/2024.02.19.580970 — bioinformatics — Posted on 2024-02-21
1420 Nitrogen metabolism in the picoalgae Pelagomonas calceolata: disentangling cyanate lyase function under different nutrient conditions.
Guerin, N.; Seyman, C.; Orvain, C.; Bertrand, L.; Gourvil, P.; Probert, I.; Vacherie, B.; Brun, E.; Magdelenat, G.; Labadie, K.; Wincker, P.; Thurotte, A.; Carradec, Q.
10.1101/2024.02.19.580968 — genomics — Posted on 2024-02-21
1421 A single E205D allele of a key P450 CYP6P3 is driving metabolic pyrethroid resistance in the major African malaria vector Anopheles gambiae
Kengne-Ouafo, J. A.; Kouamo, M.; Muhammad, A.; Tepa, A.; Ntadoun, S.; Mugenzi, L.; Tekoh, T.; Hearn, J.; Tchouakui, M.; Wondji, M.; Ibrahim, S. S.; Wondji, C. S.
10.1101/2024.02.18.580859 — genomics — Posted on 2024-02-21
1425 Effective Population Size in Field Pea
Johnson, J. P.; Piche, L.; Worral, H.; Atanda, S. A.; Coyne, C. J.; McGee, R.; McPhee, K.; Bandillo, N.
10.1101/2024.02.19.581041 — genetics — Posted on 2024-02-21
1430 A pre-vertebrate endodermal origin of calcitonin-producing neuroendocrine cells
Rees, J. M.; Kirk, K.; Gattoni, G.; Hockman, D.; Ritter, D. J.; Benito Gutierrez, E.; Knapik, E.; Crump, J. G.; Fabian, P.; Gillis, J. A.
10.1101/2024.02.17.580846 — developmental biology — Posted on 2024-02-21
1434 Real-time activity of dynorphin-expressing neurons in mouse central amygdala during alcohol drinking
Lebonville, C.; Rinker, J. A.; O'Hara, K.; McMahan, C.; Hoffman, M.; Becker, H.; Mulholland, P. J.
10.1101/2024.02.18.580880 — neuroscience — Posted on 2024-02-21
1436 POMC neurons control fertility through differential signaling of MC4R in Kisspeptin neurons in the female mouse
Talbi, R.; Stincic, T. L.; Ferrari, K.; Ji Hae, C.; Walec, K.; Medve, E.; Gerutshang, A.; Leon, S.; McCarthy, E. A.; Ronnekleiv, O. K.; Kelly, M. J.; Navarro, V. M.
10.1101/2024.02.18.580873 — neuroscience — Posted on 2024-02-21
1437 The bispectral EEG (BSEEG) method quantifies post-operative delirium-like states in young and aged mice after head mount implantation surgery
Nishiguchi, T.; Shibata, K.; Yamanishi, K.; Dittrich, M. N.; Islam, N. Y.; Patel, S.; Phuong, N. J.; Marra, P. S.; Malicoat, J. R.; Yamanashi, T.; Nishizawa, Y.; Seki, T.; Iwata, M.; Shinozaki, G.
10.1101/2024.02.17.580752 — neuroscience — Posted on 2024-02-21
1440 Lysis buffer selection guidance for mass spectrometry-based global proteomics including studies on the intersection of signal transduction and metabolism
Helm, B.; Hansen, P.; Lai, L.; Schwarzmuller, L.; Clas, S. M.; Richter, A.; Ruwolt, M.; Liu, F.; Frey, D.; DAlessandro, L. A.; Lehmann, W. D.; Schilling, M.; Helm, D.; Fiedler, D.; Klingmuller, U.
10.1101/2024.02.19.580971 — systems biology — Posted on 2024-02-21
1442 Mating-compatibility genes employed as diagnostic markers to identify novel incursions of the myrtle rust pathogen Austropuccinia psidii
Feng, J.; Bird, A.; Luo, Z.; Sheperd, L.; Murphy, L.; Singh, L.; Graetz, A.; Moeller, M.; Amorim, L.; Massola Junior, N. S.; Prodhan, A.; Shuey, L.; Beattie, D.; Gonzalez, A. T.; Tobias, P. A.; Padovan, A.; Kimber, R.; McTaggart, A.; Kehoe, M.; Schwessinger, B.; Boufleur, T. R.
10.1101/2024.02.19.580897 — plant biology — Posted on 2024-02-21
1443 MicroRNA-26b protects against MASH development and can be efficiently targeted with lipid nanoparticles.
Peters, L.; Rakateli, L.; Huchzermeier, R.; Bonnin-Marquez, A.; Maas, S. L.; Lin, C.; Jans, A.; Geng, Y.; Gorter, A.; Gijbels, M.; Rensen, S.; Olinga, P.; Hendrikx, T.; Krawczyk, M.; Brisbois, M.; Jankowski, J.; Bidzhekov, K.; Weber, C.; Biessen, E. A. L.; Shiri-Sverdlov, R.; Houben, T.; Doering, Y.; Bartneck, M.; van der Vorst, E. P. C.
10.1101/2024.02.18.580792 — pathology — Posted on 2024-02-21
1446 Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells
Santiappillai, N.; Cao, Y.; Hakeem-Sanni, M. F.; Yang, J. Y. H.; Quek, L.-E.; Hoy, A. J.
10.1101/2024.02.18.580900 — cancer biology — Posted on 2024-02-21
1447 Guidelines for QSM phantom production and evaluation ofcandidate phantom materials
Hooper, P.; Jin, J.; O'Brien, K.; Tourell, M.; Robinson, S. D.; Barth, M.
10.1101/2024.02.18.580843 — biophysics — Posted on 2024-02-21
1453 Alterations in genes associated with cytosolic RNA sensing in whole blood are associated with coronary microvascular disease in SLE
Huo, L.; Montano, E.; Tumurkhuu, G.; Bose, M.; Berman, D. S.; Wallace, D.; Wei, J.; Ishimori, M.; Merz, C. N. B.; Jefferies, C.
10.1101/2024.02.19.580713 — bioinformatics — Posted on 2024-02-21
1456 Biallelic pathogenic variants in DNAH3 cause male infertility in humans and mice
Wang, X.; Shen, G.; Yang, Y.; Jiang, C.; Ruan, T.; Yang, X.; Zhuo, L.; Zhang, Y.; Ou, Y.; Zhao, X.; Long, S.; Tang, X.; Lin, T.; Shen, Y.
10.1101/2024.02.19.580977 — genetics — Posted on 2024-02-21
1460 Stochastic regimes can hide the attractors in data, reconstruction algorithms can reveal them
M.S. Arani, B.; R. Carpenter, S.; H. van Nes, E.; A. van de Leemput, I.; Xu, C.; G. Lind, P.; Scheffer, M.
10.1101/2024.02.17.580797 — ecology — Posted on 2024-02-21
1465 Sarcomeric SRX:DRX Equilibrium in Alport and LDLR/P407 Mouse Models of HFpEF.
Kamiar, A.; Williams, M. M.; Capcha, J. M. C.; Kazmierczak, K.; Liang, J.; Lopaschuk, G. D.; Webster, K. A.; Szczesna-Cordary, D.; Shehadeh, L. A.
10.1101/2024.02.20.581314 — cell biology — Posted on 2024-02-21
1468 Assessment of the Epigenomic Landscape in Human Myometrium at Term Pregnancy
Wu, S. P. S.; Quiroz, E.; Wang, T.; Redecke, S. M.; Xu, X.; Lin, L.; Anderson, M.; DeMayo, F.
10.1101/2024.02.19.581035 — cell biology — Posted on 2024-02-21
1470 nERdy: network analysis of endoplasmic reticulum dynamics
Samudre, A.; GAO, G.; Cardoen, B.; Nabi, I. R.; Hamarneh, G.
10.1101/2024.02.20.581259 — cell biology — Posted on 2024-02-21
1472 TFEB controls syncytiotrophoblast differentiation
Esbin, M. N.; Dahal, L.; Fan, V. B.; McKenna, J. K.; Yin, E.; Darzacq, X.; Tjian, R.
10.1101/2024.02.20.581304 — cell biology — Posted on 2024-02-21
1475 Systematic mapping of MCU-mediated mitochondrial calcium signaling networks
Delgado de la Herran, H. C.; Reane, D. V.; Cheng, Y.; Katona, M.; Hosp, F.; Greotti, E.; Wettmarshausen, J.; Patron, M.; Mohr, H.; Prudente de Mello, N.; Chudenkova, M.; Gorza, M.; Walia, S.; Feng, M. S.-F.; Leimpek, A.; Mielenz, D.; Pellegata, N. S.; Langer, T.; Hajnoczky, G.; Mann, M.; Murgia, M.; Perocchi, F.
10.1101/2024.02.20.581153 — cell biology — Posted on 2024-02-21
1476 Lysine Demethylase 4A is a Centrosome Associated Protein Required for Centrosome Integrity and Genomic Stability
Chowdhury, P.; Wang, X.; Love, J. F.; Vargas-Hernandez, S.; Nakatani, Y.; Grimm, S. L.; Mezquita, D.; Mason, F. M.; Martinez, E. D.; Coarfa, C.; Walker, C. L.; Gustavsson, A.-K.; Dere, R.
10.1101/2024.02.20.581246 — cell biology — Posted on 2024-02-21
1478 Arginine Di-methylation of RIPK3 Safeguards Necroptosis for Intestinal Homeostasis
Zhang, J.; Zhao, P.; Dan, H.; Wang, Y.; Chen, X.; Jiang, X.; Shen, Y.; Wang, J.; Yang, Z.; Zhao, J.; Zhang, Y.; Zheng, J.; Liu, W.
10.1101/2024.02.21.581356 — cell biology — Posted on 2024-02-21
1480 The Alexander Disease Protein GFAP Drives Mitochondrial Fission
XIONG, D.; KONG, L.; Tan, Y. S.; YUAN, F.; SUN, Z.; LI, X.; ABELLA, E.; MESSING, A.; Zhang, S.-C.
10.1101/2024.02.20.581117 — cell biology — Posted on 2024-02-21
1481 Regionalized cell and gene signatures govern oesophageal epithelial homeostasis
Grommisch, D.; Lund, H.; Eenjes, E.; Julien, A.; Goeritz, C.; Harris, R. A.; Sandberg, R.; Hagemann-Jensen, M.; Genander, M.
10.1101/2024.02.21.581361 — cell biology — Posted on 2024-02-21
1482 Identification of SEC61B as a novel regulator of calcium flux and platelet hyperreactivity in diabetes mellitus
Kong, Y. X.; Rehan, R.; Moreno, C. L.; Madsen, S.; Zhang, Y.; Zhao, H.; Cartland, S. P.; Houlahan, C. B.; Robertshaw, D.; Trang, V.; Ong, F. J. L.; Cielesh, M.; Cooke, K. C.; Potter, M.; Stockli, J.; Morahan, G.; Kalev-Zylinska, M.; Rondina, M. T.; Schulman, S.; Yang, J. Y. H.; Neely, G. G.; James, D. E.; Kavurma, M.; Hocking, S. L.; Twigg, S.; Weaver, J.; Larance, M.; Passam, F. H.
10.1101/2024.02.20.581175 — cell biology — Posted on 2024-02-21
1483 STING contributes to pulmonary hypertension by targeting the interferon and BMPR2 signaling through regulating F2RL3
Deng, L.; Cao, C. r.; Cai, Z. y.; Wang, Z. p.; Leng, B.; Kong, F. h.; zhou, Z. y.; He, J.; Nie, X. w.; Bian, J. s.
10.1101/2024.02.20.578386 — cell biology — Posted on 2024-02-21
1484 Modulation of stress granule dynamics by phosphorylation and ubiquitination in plants
He, S.-L.; Wang, X.; Kim, S.; Kong, L.; Wang, L.; He, P.; Shan, L.; Wang, Y.; Jang, J.-C.
10.1101/2024.02.20.581253 — cell biology — Posted on 2024-02-21
1485 β2 integrins impose a mechanical checkpoint on macrophage phagocytosis
Settle, A. H.; Winer, B. Y.; de Jesus, M. M.; Seeman, L.; Wang, Z.; Chan, E.; Romin, Y.; Zhuoning, L.; Miele, M. M.; Hendrickson, R. C.; Vorselen, D.; Perry, J. S. A.; Huse, M.
10.1101/2024.02.20.580845 — cell biology — Posted on 2024-02-21
1486 Differential reorganization of episodic and semantic memory systems in epilepsy-related mesiotemporal pathology
Cabalo, D. G.; Dekraker, J.; Royer, J.; Xie, K.; Tavakol, S.; Rodriguez - Cruces, R.; Bernasconi, A.; Bernasconi, N.; Weil, A.; Pana, R.; Frauscher, B.; Caciagli, L.; Jefferies, E.; Smallwood, J.; Bernhardt, B.
10.1101/2023.09.28.560002 — neuroscience — Posted on 2024-02-21
1487 Cingulate cortex shapes early postnatal development of social vocalizations
Nagarajan, G.; Matrov, D.; Pearson, A. C.; Yen, C.; Bradley, S. P.; Chudasama, Y.
10.1101/2024.02.17.580738 — neuroscience — Posted on 2024-02-21
1488 Glutamate as a co-agonist for acid-sensing ion channels to aggravate ischemic brain damage
Lai, K.; Pritisanac, I.; Liu, Z.-Q.; Liu, H.-W.; Gong, L.-N.; Li, M.-X.; Lu, J.-F.; Qi, X.; Xu, T.-L.; Forman-Kay, J. D.; Shi, H.-B.; Wang, L.-Y.; Yin, S.
10.1101/2024.02.17.580727 — neuroscience — Posted on 2024-02-21
1490 Exploring an EM-algorithm for banded regression in computational neuroscience
Fuglsang, S. A.; Madsen, K. H.; Puonti, O.; Siebner, H. R.; Hjortkjaer, J.
10.1101/2023.09.22.558945 — neuroscience — Posted on 2024-02-21
1494 Mechano-inhibition of Endocytosis Sensitizes Cancer Cells to Fas-induced Apoptosis
Kural, M.; Djakbarova, U.; Cakir, B.; Tanaka, Y.; Madraki, Y.; Chan, E. T.; Arteaga Muniz, V.; Qian, H.; Park, J.; Sewanan, L.; Park, I.-H.; Niklason, L.; Kural, C.
10.1101/2022.06.14.496195 — cancer biology — Posted on 2024-02-21
1498 Unveiling Inter-Embryo Variability in Spindle Length over time: towards Quantitative Phenotype Analysis.
Le Cunff, Y.; Chesneau, L.; Pastezeur, S.; Pinson, X.; Soler, N.; Fairbrass, D.; Mercat, B.; Rodriguez Garcia, R.; Alayan, Z.; Abdouni, A.; de Neidhardt, G.; Costes, V.; Anjubault, M.; Bouvrais, H.; Heligon, C.; Pecreaux, J.
10.1101/2023.05.01.538870 — bioinformatics — Posted on 2024-02-21
1499 Discovery of free glycated amines and glycated urea as potential markers of diabetic nephropathy
Shaikh, R. Q.; Das, S.; Chaurasiya, A. H.; Ashtamy, M. G.; Sheikh, A. B.; Fernandes, M.; Tiwari, S.; Unnikrishnan, A. G.; Kulkarni, M.
10.1101/2024.02.17.580794 — biochemistry — Posted on 2024-02-21
1500 Multi-trait multi-environment genomic prediction of preliminary yield trials in pulse crops
Saludares, R. A. G.; Atanda, S. A.; Piche, L.; Worral, H.; Dariva, F.; McPhee, K.; Bandillo, N.
10.1101/2024.02.18.580909 — genomics — Posted on 2024-02-21
1502 Genetic Modulation of Protein Expression in Rat Brain
li, L.; Wu, Z.; Guarracino, A.; Villani, F.; Kong, D.; Mancieri, A.; Zhang, A.; Saba, L. M.; Chen, H.; Brozka, H.; Vales, K.; Senko, A. N.; Kempermann, G.; Stuchlik, A.; Pravenec, M.; Prins, P.; Peng, J.; Wang, X.
10.1101/2024.02.17.580840 — genetics — Posted on 2024-02-21
1503 Chromosomal inversions harbour excess mutational load in the coral, Acropora kenti, on the Great Barrier Reef
Zhang, J.; Schneller, N. M.; Field, M. A.; Chan, C. X.; Miller, D. J.; Strugnell, J. M.; Riginos, C.; Bay, L.; Cooke, I. R.
10.1101/2024.02.19.580031 — evolutionary biology — Posted on 2024-02-21
1508 MATEdb2, a collection of high-quality metazoan proteomes across the Animal Tree of Life to speed up phylogenomic studies
Martinez-Redondo, G. I.; Vargas-Chavez, C.; Eleftheriadi, K.; Benitez-Alvarez, L.; Vazquez-Valls, M.; Fernandez, R.
10.1101/2024.02.21.581367 — evolutionary biology — Posted on 2024-02-21
1510 The satiety hormone cholecystokinin gates reproduction in fish by controlling gonadotropin secretion
Hollander cohen, L.; Cohen, O.; Shulman, M.; Aiznkot, T.; Fontanaud, P.; Revah, O.; Mollard, P.; Golan, M.; Levavi Sivan, B.
10.1101/2023.06.18.545454 — neuroscience — Posted on 2024-02-21
1514 Pectin methylesterase activity is required for RALF1 peptide signalling output
Roessling, A.-K.; Dunser, K.; Liu, C.; Lauw, S.; Rodriguez- Franco, M.; Kalmbach, L.; Barbez, E.; Kleine-Vehn, J.
10.1101/2023.08.18.553913 — plant biology — Posted on 2024-02-21
1515 ModiFinder: Tandem Mass Spectral Alignment Enables Structural Modification Site Localization
Shahneh, M. R. Z.; Strobel, M.; Vitale, G. A.; Geibel, C.; El Abiead, Y.; Garg, N.; Aron, A. T.; Phelan, V. V.; Petras, D.; Wang, M.
10.1101/2024.02.17.580849 — bioinformatics — Posted on 2024-02-21
1517 Comparative Multi-omic Mapping of Human Pancreatic Islet Endoplasmic Reticulum and Cytokine Stress Responses Provides Insights into Type 2 Diabetes Genetics
Sokolowski, E. K.; Kursawe, R.; Selvam, V.; Bhuiyan, R. M.; Thibodeau, A.; Zhao, C.; Spracklen, C. N.; Ucar, D.; Stitzel, M. L.
10.1101/2024.02.17.580646 — genomics — Posted on 2024-02-21
1521 From Sight to Insight: A Multi-task Approach with the Visual Language Decoding Model
Huang, W.; Yang, P.; Tang, Y.; Qin, F.; Li, H.; Wu, D.; Ren, W.; Wang, S.; Zhao, Y.; Wang, J.; Liu, H.; Li, J.; Zhu, Y.; Zhou, B.; Sun, J.; Li, Q.; Cheng, K.; Yan, H.; Chen, H.
10.1101/2024.02.16.580578 — neuroscience — Posted on 2024-02-21
1524 A candidate sex determination locus in amphibians, evolved by structural variation between X- and Y-chromosomes
Kuhl, H.; Tan, W.-H.; Klopp, C.; Kleiner, W.; Koyun, B.; Ciorpac, M.; Feron, R.; Knytl, M.; Kloas, W.; Schartl, M.; Winkler, C. W.; Stoeck, M.
10.1101/2023.10.20.563234 — genomics — Posted on 2024-02-21
1525 Sex-biased regulatory changes in the placenta of native highlanders contribute to adaptive fetal development
Yue, T.; Guo, Y.; Qi, X.; Zheng, W.; Zhang, H.; Wang, B.; Zhou, B.; Zeng, X.; NA, O.; He, Y.; Su, B.
10.1101/2023.05.24.542081 — evolutionary biology — Posted on 2024-02-21
1527 Epigenetic age estimation of wild mice using faecal samples
Hanski, E.; Joseph, S.; Raulo, A.; Wanelik, K.; O'Toole, A.; Knowles, S. C. L.; Little, T. J.
10.1101/2023.10.25.563913 — molecular biology — Posted on 2024-02-21
1528 Gene-Dose-Dependent Reduction Fshr Expression Improves Spatial Memory Deficits in Alzheimer's Mice
Korkmaz, F.; Sims, S.; Sen, F.; Sultana, F.; Laurencin, V.; Cullen, L.; Pallapati, A. R.; Liu, A.; Rojekar, S.; Pevnev, G.; Cheliadinova, U.; Vasilyeva, D.; Burganova, G.; Macdonald, A.; Saxena, M.; Goosens, K.; Rosen, C.; Barak, O.; Lizneva, D.; Gumerova, A.; Ye, K.; Ryu, V.; Yuen, T.; Frolinger, T.; Zaidi, M.
10.1101/2024.02.16.580761 — neuroscience — Posted on 2024-02-21
1530 Epigenetic repression of cFos supports sequential formation of distinct spatial memories
Franzelin, A.; Lamothe-Molina, P. J.; Gee, C. E.; Formozov, A.; Schreiter, E. R.; Morellini, F.; Oertner, T. G.
10.1101/2024.02.16.580703 — neuroscience — Posted on 2024-02-21
1535 Blocking Interleukin-1beta transiently limits left ventricular dilation and reduces cardiac lymphangiogenesis in a mouse pressure-overload model
Heron, C.; Lemarcis, T.; Bundalo, M.; Laguerre, O.; Valentin, C.; Valet, M.; Michel, J.-B.; Mulder, P.; Zernecke, A.; Tardif San Martin, V.; Brakenhielm, E.
10.1101/2023.04.01.535056 — physiology — Posted on 2024-02-21
1538 Evidence for a transfer-to-trap mechanism of fluorophore concentration quenching in lipid bilayers
Meredith, S. A.; Kusunoki, Y.; Evans, S. D.; Morigaki, K.; Connell, S. D.; Adams, P. G.
10.1101/2024.02.16.580699 — biophysics — Posted on 2024-02-21
1539 Characterization of an amyloidogenic intermediate of transthyretin by NMR relaxation dispersion
Leach, B. I.; Ferguson, J. A.; Morgan, G. J.; Sun, X.; Kroon, G.; Oyen, D.; Dyson, J.; Wright, P.
10.1101/2024.02.16.580707 — biophysics — Posted on 2024-02-21
1542 ProHap enables proteomic database generation accounting for population diversity
Vasicek, J.; Kuznetsova, K. G.; Skiadopoulou, D.; Johansson, S.; Njolstad, P. R.; Bruckner, S.; Kall, L.; Vaudel, M.
10.1101/2023.12.24.572591 — bioinformatics — Posted on 2024-02-21
1545 First chromosome-level genome assembly of a ribbon worm from the Hoplonemertea clade, Emplectonema gracile, and its structural annotation
Valero-Gracia, A.; Roberts, N. G.; Yap-Chiongco, M.; Capucho, A. T.; Kocot, K. M.; Matschiner, M.; Struck, T. H.
10.1101/2024.02.16.580704 — genomics — Posted on 2024-02-21
1546 Screening and assessment of functional variants by regulatory features from epigenomic data in livestock species
Ma, R.; Kuang, R.; Zhang, J.; Xu, Y.; Han, Z.; Hu, M.; Wang, D.; Luan, Y.; Fu, Y.; Zhang, Y.; Li, X.; Zhu, M.; Xiang, T.; Zhao, S.; Zhao, Y.
10.1101/2024.02.06.578787 — genomics — Posted on 2024-02-21
1547 Diploid genome assembly of the Malbec grapevine cultivar enables haplotype-aware analysis of transcriptomic differences underlying clonal phenotypic variation
Calderon, L.; Carbonell-Bejerano, P.; Munoz, C.; Bree, L.; Sola, C.; Bergamin, D.; Tulle, W.; Gomez-Talquenca, S.; Lanz, C.; Royo, C.; Ibanez, J.; Martinez-Zapater, J. M.; Weigel, D.; Lijavetzky, D.
10.1101/2023.11.30.569420 — genomics — Posted on 2024-02-21
1549 Small-molecule-based regulation of gene expression in human astrocytes upon both positive and negative actuations of G-quadruplex control systems
Kumar, M. J. V.; Mitteaux, J.; Wang, Z.; Wheeler, E.; Tandon, N.; Jung, S. Y.; Hudson, R. H. E.; Monchaud, D.; Tsvetkov, A. S.
10.1101/2024.02.16.580621 — genetics — Posted on 2024-02-21
1552 Microtubule forces drive nuclear damage in LMNA cardiomyopathy
Amiad Pavlov, D.; Corredera, C. S.; Dehghany, M.; Heffler, J.; Shen, K. M.; Zuela-Sopilniak, N.; Randell, R.; Uchida, K.; Jain, R.; Shenoy, V.; Lammerding, J.; Prosser, B. L.
10.1101/2024.02.10.579774 — cell biology — Posted on 2024-02-21
1556 When most fMRI connectivity cannot be detected: insights from time course reliability
Koten, J. W.; Manner, H.; Pernet, C.; Schüppen, A.; Szücs, D.; Wood, G.; Ioannidis, J.
10.1101/2024.02.16.580783 — neuroscience — Posted on 2024-02-21
1557 DDHD2 provides a critical flux of saturated fatty acids to support neuronal energy demands
Saber, S. H.; Yak, N.; Yong, X. L. H.; Binder, T.; Lu, S.; Koludarova, L.; Purushothaman, R.; Er, S.; Hlushchuk, I.; Gaudin, A.; Nyman, T.; Harmer, J.; Talbo, G. H.; Airavaara, M.; Battersby, B.; van Waardenberg, A. J.; Anggono, V.; Balistreri, G.; Joensuu, M.
10.1101/2023.12.31.573799 — neuroscience — Posted on 2024-02-21
1558 Root Expansion Microscopy (ROOT-ExM): A streamlined super resolution method for plants
GRISON, M. S.; Maucort, G.; Dumazel, A.; Champelovier, D.; BOUTTE, Y.; Fernandez-Monreal, M.; Bayer, E.
10.1101/2024.02.21.581184 — plant biology — Posted on 2024-02-21
1560 Interplay between Mg2+ and Ca2+ at multiple sites of the ryanodine receptor
Samso, M.; Nayak, A. R.; Rangubpit, W.; Will, A. H.; Hu, Y.; Castro-Hartmann, P.; Lobo, J. J.; Dryden, K.; Lamb, G. D.; Sompornpisut, P.
10.1101/2024.02.16.580716 — biophysics — Posted on 2024-02-21
1563 The Representation of Decision Variables in Orbitofrontal Cortex is Longitudinally Stable
Zhang, M.; Livi, A.; Carter, M.; Schoknecht, H.; Burkhalter, A.; Holy, T. E.; Padoa-Schioppa, C.
10.1101/2024.02.16.580715 — neuroscience — Posted on 2024-02-21
1564 AIBP controls amyloid beta induced TLR4 inflammarafts and mitochondrial dysfunction in microglia
Kim, Y. S.; CHOI, S.-H.; Kim, K.-Y.; Navia Pelaez, J. M.; Perkins, G. A.; Choi, S.; Miller, N. N.; Kim, J.; Ju, W.; Rissman, R. A.; Ellisman, M. H.; Miller, Y. I.
10.1101/2024.02.16.580751 — neuroscience — Posted on 2024-02-21
1565 Human spinal cord activation during filling and emptying of the bladder
Agyeman, K. A.; Lee, D. J.; Abedi, A.; Sakellaridi, S.; Kreydin, E.; Russin, J.; Lo, J. T.; Wu, K.; Choi, W.; Edgerton, R. V.; Liu, C.; Christopoulos, V. N.
10.1101/2024.02.16.580736 — neuroscience — Posted on 2024-02-21
1566 SCN gene expression plasticity in response to photoperiod
Cox, O. H.; Giannoni-Guzman, M. A.; Cartailler, J.-P.; Cottam, M. A.; McMahon, D. G.
10.1101/2024.02.16.580759 — neuroscience — Posted on 2024-02-21
1567 Super-resolution expansion microscopy in plant roots
Gallei, M.; Truckenbrodt, S.; Kreuzinger, C.; Inumella, S.; Vistunou, V.; Sommer, C.; Tavakoli, M. R.; Agudelo-Duenas, N.; Vorlaufer, J.; Jahr, W.; Randuch, M.; Johnson, A.; Benkova, E.; Friml, J.; Danzl, J. G.
10.1101/2024.02.21.581330 — plant biology — Posted on 2024-02-21
1568 Signaling and transcriptional dynamics underlying early adaptation to oncogenic BRAF inhibition
Flower, C. T.; Liu, C.; Chuang, H.-Y.; Ye, X.; Cheng, H.; Heath, J. R.; Wei, W.; White, F. M.
10.1101/2024.02.19.581004 — systems biology — Posted on 2024-02-21
1569 Towards Effective CAIX-targeted Radionuclide and Checkpoint Inhibition Combination Therapy for Advanced Clear Cell Renal Cell Carcinoma
Kleinendorst, S. C.; Oosterwijk, E.; Molkenboer-Kuenen, J.; Frielink, C.; Franssen, G.; Boreel, D. F.; Tamborino, G.; Gloudemans, M.; Hendrikx, M.; Kroon, D.; Hillen, J.; Bussink, J.; Muselaers, S.; Mulders, P.; Konijnenberg, M. W.; Wheatcroft, M. P.; Twumasi-Boateng, K.; Heskamp, S.
10.1101/2024.02.16.580614 — cancer biology — Posted on 2024-02-21
1570 Perivascular cells function as mechano-structural sensors of vascular capillaries
Franca, C. M.; Lima Verde, M. E.; Silva-Sousa, A. C.; Mansoorifar, A.; Athirasala, A.; Subbiah, R.; Tahayeri, A.; Sousa, M.; Fraga, M. A.; Visalakshan, R.; Doe, A.; Beadle, K.; Finley, M.; Dimitriadis, E.; Bays, J.; Uroz, M. M.; Yamada, K. M.; Chen, C. S.; Bertassoni, L. E.
10.1101/2024.02.16.580564 — bioengineering — Posted on 2024-02-21
1571 Oleic acid triggers CD4+ T cells to be metabolically rewired and poised to differentiate into proinflammatory T cell subsets upon activation
Reilly, N. A.; Sonnet, F.; Dekkers, K. F.; Kwekkeboom, J. C.; Sinke, L.; Hilt, S.; Suleiman, H. M.; Hoeksema, M. A.; Mei, H.; van Zwet, E. W.; Everts, B.; Ioan-Facsinay, A.; Jukema, J. W.; Heijmans, B. T.
10.1101/2024.02.16.580665 — genomics — Posted on 2024-02-21
1572 The genome of Przewalski's horse (Equus ferus przewalskii)
Flack, N.; Hughes, L.; Cassens, J.; Enriquez, M.; Gebeyehu, S.; Alshagawi, M.; Hatfield, J.; Kauffman, A.; Brown, B.; Klaeui, C.; Malbrouk, I. F.; Walls, C.; Yeater, T.; Rivas, A.; Faulk, C.
10.1101/2024.02.20.581252 — genomics — Posted on 2024-02-21
1574 Impact of a national tsetse control programme to eliminate Gambian sleeping sickness in Uganda: a spatio-temporal modelling study.
Longbottom, J.; Esterhuizen, J.; Hope, A.; Lehane, M. J.; Mangwiro, C. T.; Mugenyi, A.; Dunkley, S.; Selby, R.; Tirados, I.; Torr, S. J.; Stanton, M. C.
10.1101/2024.02.16.580671 — ecology — Posted on 2024-02-21
1577 Dnmt3a mutations limit normal and autoreactive Tfh differentiation
Shen, Y.; Li, Z.; Boddul, S. V.; Kasza, Z.; Espinosa, A.; Klareskog, L.; Wermeling, F.
10.1101/2024.02.16.580463 — immunology — Posted on 2024-02-21
1578 An extremely fast neural mechanism to detect emotional visual stimuli: A two-experiment study
Carretie, L.; Fernandez-Folgueiras, U.; Kessel, D.; Alba, G.; Estrella, V.-Z.; Tapia, M.; Alvarez, F.
10.1101/2024.02.16.580636 — neuroscience — Posted on 2024-02-21
1581 Multi-orientation U-Net for Super-Resolution of Ultra-Low-Field Paediatric MRI
Baljer, L.; Zhang, Y.; Bourke, N. J.; Donald, K. A.; Bradford, L. E.; Ringshaw, J. E.; Williams, S. R.; Deoni, S. C.; Williams, S. C.; Khula SA Study Team, ; Vasa, F.; Moran, R. J.
10.1101/2024.02.16.580639 — neuroscience — Posted on 2024-02-21
1583 Apnoea suppresses brain activity in infants
Zandvoort, C. S.; Dereymaeker, A.; Baxter, L.; Jansen, K.; Naulaers, G.; de Vos, M.; Hartley, C.
10.1101/2024.02.16.580547 — neuroscience — Posted on 2024-02-21
1584 Selective deletion of interleukin-1 alpha in microglia regulates neuronal activity and neurorepair processes after experimental ischemic stroke.
Lemarchand, E.; Grayston, A.; Wong, R.; Rogers, M.; Ouvrier, B.; Llewellyn, B.; Webb, F.; Brough, D.; Allan, S. M.; Bix, G.; Pinteaux, E.
10.1101/2024.02.16.580635 — neuroscience — Posted on 2024-02-21
1585 Circadian clocks in human cerebral organoids
Rzechorzek, N. M.; Sutcliffe, M. A.; Mihut, A.; Baranes, K.; Karam, N.; Lloyd-Davies Sanchez, D.; Peak-Chew, S. Y.; Zeng, A.; Poulin, N.; Seinkmane, E.; Karim, K.; Proctor, C. M.; Kotter, M.; Lancaster, M. A.; Beale, A. D.
10.1101/2024.02.20.580978 — neuroscience — Posted on 2024-02-21
1586 An axonal brake on striatal dopamine output by cholinergic interneurons
Zhang, Y.-F.; Luan, P.; Qiao, Q.; He, Y.; Zatka-Haas, P.; Zhang, G.; Lin, M.; Lak, A.; Jing, M.; Mann, E. O.; Cragg, S.
10.1101/2024.02.17.580796 — neuroscience — Posted on 2024-02-21
1587 Neuronal-class specific molecular cues drive differential myelination in the neocortex
Jokhi, V.; Dominguez-Iturza, N.; Kim, K.; Shetty, A. S.; Yuan, W.; Di Bella, D.; Abbate, C.; Oyler-Castrillo, P.; Jin, X.; Simmons, S.; Levin, J. Z.; Brown, J. R.; Arlotta, P.
10.1101/2024.02.20.581268 — neuroscience — Posted on 2024-02-21
1590 An interim exploratory biomarker analysis of a Phase 2 clinical trial to assess the impact of CT1812 in Alzheimers disease
Lizama, B. N.; North, H. A.; Pandey, K.; Williams, C.; Duong, D.; Cho, E.; Di Caro, V.; Ping, L.; Blennow, K.; Zetterberg, H.; Lah, J. J.; Levey, A. I.; Grundman, M.; Caggiano, A. O.; Seyfried, N. T.; Hamby, M. E.
10.1101/2024.02.16.578765 — neuroscience — Posted on 2024-02-21
1591 Chromatin regulator Kdm6b is required for the establishment and maintenance of neural stem cells in mouse hippocampus
Gil, E.; Hong, S. J.; Wu, D.; Park, D. H.; Delgado, R. N.; Malatesta, M.; Ahanger, S. H.; Lin, K.; Villeda, S.; Lim, D.
10.1101/2024.02.20.581302 — neuroscience — Posted on 2024-02-21
1594 Opposing roles of physiological and pathological amyloid-β on synapses in live human brain slice cultures
McGeachan, R. I.; Meftah, S.; Taylor, L. W.; Catterson, J. H.; Negro, D.; Tulloch, J.; Rose, J. L.; Gobbo, F.; Liaquat, I.; Spires-Jones, T. L.; Booker, S. A.; Brennan, P. M.; Durrant, C. S.
10.1101/2024.02.16.580676 — neuroscience — Posted on 2024-02-21
1595 A deep learning-based toolkit for 3D nuclei segmentation and quantitative analysis in cellular and tissue context
Vijayan, A.; Mody, T. A.; Yu, Q.; Wolny, A.; Cerrone, L.; Strauss, S.; Tsiantis, M.; Smith, R. S.; Hamprecht, F.; Kreshuk, A.; Schneitz, K.
10.1101/2024.02.19.580954 — plant biology — Posted on 2024-02-21
1596 Efficient targeting of heart lesions with cardiac myofibroblasts: Combined gene and cell therapy enhanced by magnetic steering
Schiffer, M.; Wagner, K.; Carls, E.; Nicke, J.; Hesse, M.; Fratila, R.; Hildebrand, S.; Pfeifer, A.; Eberbeck, D.; Malek Mohammadi, M.; de la Fuente, J. M.; Fleischmann, B. K.; Roell, W.
10.1101/2024.02.16.580672 — physiology — Posted on 2024-02-21
1597 Label-free phenotyping of human microvessel networks
Rappez, L.; Akinbote, A.; Cherubini, M.; Uhlmann, V.; Haase, K.
10.1101/2024.02.20.581133 — bioengineering — Posted on 2024-02-21
1600 The sperm hook in house mice: a functional adaptation for migration and self-organised behaviour
Ryu, H.; Nam, K.; Lee, B. E.; Jeong, Y.; Lee, S.; Kim, J.; Hyun, Y.-M.; Kim, J.-I.; Park, J.-H.
10.1101/2024.02.19.581047 — cell biology — Posted on 2024-02-21
1602 Profiling Glioma Stem Cell Dynamics via 3D-based Cell Cycle Reporter Assays
Lubanska, D.; Roye-Azar, A.; Alrashed, S.; Cieslukowski, A.; Soliman, M.; deCarvalho, A. C.; Shamisa, A.; Kulkarni, S.; Porter, L.
10.1101/2024.02.16.580653 — cancer biology — Posted on 2024-02-20
1604 Mapping the Single-cell Differentiation Landscape of Osteosarcoma
Truong, D. D.; Weistuch, C.; Murgas, K. A.; Admane, P.; King, B. L.; Chauviere Lee, J.; Lamhamedi-Cherradi, S.-E.; Swaminathan, J.; Daw, N. C.; Gordon, N.; Gopalakrishnan, V.; Gorlick, R. G.; Somaiah, N.; Deasy, J. O.; Mikos, A. G.; Tannenbaum, A.; Ludwig, J.
10.1101/2023.09.13.555156 — cancer biology — Posted on 2024-02-20
1605 An atlas of epithelial cell states and plasticity in lung adenocarcinoma
Han, G.; Sinjab, A.; Rahal, Z.; Lynch, A. M.; Treekitkarnmongkol, W.; Liu, Y.; Serrano, A. G.; Feng, J.; Liang, K.; Khan, K.; Lu, W.; Hernandez, S.; Liu, Y.; Cao, X.; Dai, E.; Pei, G.; Hu, J.; Abaya, C.; Gomez-Bolanoz, L. I.; Peng, F.; Chen, M.; Parra, E. R.; Cascone, T.; Sepesi, B.; Moghaddam, S. J.; Scheet, P.; Negrano, M. V.; Heymach, J. V.; Li, M.; Dubinett, S. M.; Stevenson, C. S.; Spira, A. E.; Fujimoto, J.; Solis, L. M.; Wistuba, I. I.; Chen, J.; Wang, L.; Kadara, H.
10.1101/2022.05.13.491635 — cancer biology — Posted on 2024-02-20
1606 Large-pore connexin hemichannels function as molecule transporters independently of ion conduction
Gaete, P. S.; Kumar, D.; Fernandez, C. I.; Valdez-Capuccino, J. M.; Bhatt, A.; Jiang, W.; Lin, Y.; Liu, Y.; Harris, A. L.; Luo, Y. L.; Contreras, J. E.
10.1101/2024.02.20.581300 — biophysics — Posted on 2024-02-20
1610 RNA dicing regulates the expression of an oncogenic JAK1 isoform
Malka, Y.; van der Kammen, R.; Ju, S.; Alkan, F.; Lee, C.; Faller, W. J.
10.1101/2024.02.20.581186 — molecular biology — Posted on 2024-02-20
1613 Essential magnetosome proteins MamI and MamL from magnetotactic bacteria interact in mammalian cells
Sun, Q.; Yu, L.; Donnelly, S. C.; Fradin, C.; Thompson, R. T.; Prato, F. S.; Goldhawk, D. E.
10.1101/2023.12.19.572379 — synthetic biology — Posted on 2024-02-20
1616 50,000 years of Evolutionary History of India: Insights from ~2,700 Whole Genome Sequences
Kerdoncuff, E.; Skov, L.; Patterson, N.; Zhao, W.; Lueng, Y. Y.; Schellenberg, G. D.; Smith, J. A.; Dey, S.; Ganna, A.; Dey, A.; Kardia, S. L. R.; Lee, J.; Moorjani, P.
10.1101/2024.02.15.580575 — evolutionary biology — Posted on 2024-02-20
1617 Rapid Human Oogonia-like Cell Specification via Combinatorial TF-Directed Differentiation
Smela, M. P.; Kramme, C.; Fortuna, P. R.; Wolf, B.; Kavirayuni, V. S.; Adams, J. L.; Ma, C.; Velychko, S.; Widocki, U.; Goel, S.; Chen, T.; Vincoff, S.; Dong, E.; Kohman, R. E.; Kobayashi, M.; Shioda, T.; Church, G. M.; Chatterjee, P.
10.1101/2022.07.11.499564 — developmental biology — Posted on 2024-02-20
1621 Re-coding of G protein-coupled receptor signaling enables emergent cellular behavior.
Dehkhoda, F.; Ringuet, M.; Whitfield, E. A.; Mutunduwe, K.; Nowell, C. J.; Misganaw, D.; Xu, Z.; Hossain, A. M.; Fothergill, L. J.; McDougall, S. J.; Furness, J. B.; Furness, S. G. B.
10.1101/2023.12.18.572241 — cell biology — Posted on 2024-02-20
1624 Resting EEG Periodic and Aperiodic Components Predict Cognitive Decline Over 10 Years
Finley, A. J.; Angus, D. J.; Knight, E. L.; van Reekum, C. M.; Lachman, M. E.; Davidson, R. J.; Schaefer, S. M.
10.1101/2023.07.17.549371 — neuroscience — Posted on 2024-02-20
1625 Multiple objects evoke fluctuating responses in several regions of the visual pathway
Schmehl, M. N.; Caruso, V. C.; Chen, Y.; Jun, N. Y.; Willett, S. M.; Mohl, J. T.; Ruff, D. A.; Cohen, M. R.; Ebihara, A.; Freiwald, W.; Tokdar, S. T.; Groh, J. M.
10.1101/2023.07.19.549668 — neuroscience — Posted on 2024-02-20
1633 Evolutionary genomics of the emergence of brown algae as key components of coastal ecosystems
Denoeud, F.; Godfroy, O.; Cruaud, C.; Heesch, S.; Nehr, Z.; Tadrent, N.; Couloux, A.; Brillet-Gueguen, L.; Delage, L.; Dean, D.; Motomura, T.; Sussfeld, D.; Fan, X.; Mazeas, L.; Terrapon, N.; Barrera-Redondo, J.; Petroll, R.; Reynes, L.; Choi, S.-W.; Jo, J.; Uthanumallian, K.; Bogaert, K.; Duc, C.; Ratchinski, P.; Lipinska, A.; Noel, B.; Murphy, E. A.; Lohr, M.; Khatei, A.; Hamon-Giraud, P.; Vieira, C.; Akerfors, S. S.; Akita, S.; Avia, K.; Badis, Y.; Barbeyron, T.; Belcour, A.; Berrabah, W.; Blanquart, S.; Bouguerba, A.; Bringloe, T. T.; Cattolico, R. A.; Cormier, A.; Cruz de Carvalho, M. H.;
10.1101/2024.02.19.579948 — genomics — Posted on 2024-02-20
1636 Reverse Engineering of Feedforward Cortical-Hippocampal Microcircuits for Modelling Neural Network Function and Dysfunction
Hanssen, K. S.; Winter-Hjelm, N.; Niethammer, S. N.; Kobro-Flatmoen, A.; Witter, M. P.; Sandvig, A.; Sandvig, I.
10.1101/2023.06.26.546556 — neuroscience — Posted on 2024-02-20
1637 Cross-species modeling and enhancement of cognitive control with striatal brain stimulation
Reimer, A. E.; Dastin-van Rijn, E. M.; Kim, J.; Mensinger, M. E.; Sachse, E. M.; Wald, A.; Hoskins, E.; Singh, K.; Alpers, A.; Cooper, D.; Lo, M.-C.; de Oliveira, A. R.; Simandl, G.; Stephenson, N.; Widge, A. S.
10.1101/2024.02.16.580680 — neuroscience — Posted on 2024-02-20
1638 Binding of cortical functional modules by synchronous high frequency oscillations
Garrett, J. C.; Verzhbinsky, I. A.; Kaestner, E.; Carlson, C.; Doyle, W. K.; Devinsky, O.; Thesen, T.; Halgren, E.
10.1101/2023.05.20.541597 — neuroscience — Posted on 2024-02-20
1639 From Sight to Insight: A Multi-task Approach with the Visual Language Decoding Model
Huang, W.; Yang, P.; Tang, Y.; Qin, F.; Li, H.; Wu, D.; Ren, W.; Wang, S.; Zhao, Y.; Wang, J.; Liu, H.; Li, J.; Zhu, Y.; Zhou, B.; Sun, J.; Li, Q.; Cheng, K.; Yan, H.; Chen, H.
10.1101/2024.02.16.580578 — neuroscience — Posted on 2024-02-20
1641 ARTseq-FISH reveals position-dependent differences in gene expression of micropatterned mESCs
Hu, X.; van Sluijs, B.; Garcia Blay, O.; Stepanov, Y.; Rietrae, K.; Huck, W.; Hansen, M. M. K.
10.1101/2022.09.14.507902 — systems biology — Posted on 2024-02-20
1642 Chronic Stress effects on Immune-Neuroendocrine matrix in Coturnix japonica, analyses from an ontogenetic perspective
Marozzi, A.; Correa, S. G.; Palme, R.; Cantarelli, V. I.; Ponzio, M. F.; Marin, R. H.; Nazar, F. N.
10.1101/2024.01.24.577005 — physiology — Posted on 2024-02-20
1644 Secondary structure determines electron transport in peptides
Samajdar, R.; Meigooni, M.; Yang, H.; Li, J.; Liu, X.; Jackson, N. E.; Mosquera, M. A.; Tajkhorshid, E.; Schroeder, C. M.
10.1101/2024.02.18.578245 — biophysics — Posted on 2024-02-20
1648 An open-source MRI compatible frame for multimodal presurgical mapping in macaque and capuchin monkeys
Liang, L.; Zimmermann Rollin, I.; Alikaya, A.; Ho, J. C.; Santini, T.; Bostan, A. C.; Schwerdt, H. N.; Stauffer, W. R.; Ibrahim, T. S.; Pirondini, E.; Schaeffer, D.
10.1101/2024.02.17.580767 — bioengineering — Posted on 2024-02-20
1652 Retrotransposon-mediated variation of a chitin synthase gene confers insect resistance to Bacillus thuringiensis Vip3Aa toxin
Liu, Z.; Liao, C.; Zou, L.; Jin, M.; Shan, Y.; Quan, Y.; Yao, H.; Zhang, L.; Wang, P.; Liu, Z.; Wang, N.; Li, A.; Liu, K.; Heckel, D. G.; Wu, K.; Xiao, Y.
10.1101/2024.02.18.580648 — genetics — Posted on 2024-02-20
1653 Sequence-based genome-wide association studies reveal the polygenic architecture of Varroa destructor resistance in Western honey bees Apis mellifera
Eynard, S. E.; Mondet, F.; Basso, B.; Bouchez, O. E.; Bulach, T.; Le Conte, Y.; Dainat, B.; Decourtye, A.; Genestout, L.; Guichard, M.; Guillaume, F.; Labarthe, E.; Locke, B.; Mahla, R.; de Miranda, J. R.; Neuditschko, M.; Phocas, F.; Poquet, Y.; Sann, C.; Serre, R.-F.; Tabet, K.; Vignal, A.; Servin, B.
10.1101/2024.02.16.580755 — genetics — Posted on 2024-02-20
1654 A tale of too many trees: a conundrum for phylogenetic regression
Adams, R.; Roa Lozano, J.; Duncan, M.; Green, J.; Assis, R.; DeGiorgio, M.
10.1101/2024.02.16.580530 — evolutionary biology — Posted on 2024-02-20
1656 High-resolution lineage tracking of within-host evolution and strain transmission in a human gut symbiont across ecological scales
Vasquez, K. S.; Wong, D. P. G. H.; Pedro, M. F.; Yu, F. B.; Jain, S.; Meng, X.; Higginbottom, S. K.; DeFelice, B. C.; Neff, N.; Bhatt, A. S.; Tropini, C.; Xavier, K. B.; Sonnenburg, J. L.; Good, B. H.; Huang, K. C.
10.1101/2024.02.17.580834 — evolutionary biology — Posted on 2024-02-20
1662 Unraveling the gut microbiota of Tibetan chickens: insights into highland adaptation and ecological advantages
Zeng, T.; Cao, Y.; Yin, J.; Feng, P.; TIAN, Y.; Sun, H.; GU, T.; Zong, Y.; Ma, X.; Zhao, Z.; Chen, L.; XU, W.; Han, W.; Lu, L.
10.1101/2024.02.19.581084 — microbiology — Posted on 2024-02-20
1664 A difficult coexistence: resolving the iron-induced nitrification delay in groundwater filters
Corbera-Rubio, F.; Kruisdijk, E.; Malheiro, S.; Leblond, M.; Verschoor, L.; van Loosdrecht, M.; Laureni, M.; van Halem, D.
10.1101/2024.02.19.581000 — microbiology — Posted on 2024-02-20
1666 Directed evolution of a bacterial leucyl tRNA in mammalian cells for enhanced noncanonical amino acid mutagenesis
Huang, R. L.; Jewel, D.; Kelemen, R. E.; Pham, Q.; Wang, S.; Roy, S. J. S.; Huang, Z.; Levinson, S. D.; Sundaresh, B.; Miranda, S. E.; van Opijnen, T.; Chatterjee, A.
10.1101/2024.02.19.581038 — synthetic biology — Posted on 2024-02-20
1668 A Novel Support Vector Machine-Based One-Day, Single-Dose Prediction Model of Genotoxic Hepatocarcinogenicity in Rats
Gi, M.; Suzuki, S.; Kanki, M.; Yokohira, M.; Tsukamoto, T.; Fujioka, M.; Vachiraarunwong, A.; Qiu, G.; Guo, R.; Wanibuchi, H.
10.1101/2024.02.19.579908 — pharmacology and toxicology — Posted on 2024-02-20
1669 The Strongest Protein Binder is Surprisingly Labile
Fernandez-Calvo, A.; Reifs, A.; Saa, L.; Cortajarena, A. L.; De Sancho, D.; Perez-Jimenez, R.
10.1101/2024.02.18.580677 — biophysics — Posted on 2024-02-20
1671 Transcriptional perturbation of LINE-1 elements reveals their cis-regulatory potential
Perez-Rico, Y. A.; Bousard, A.; Misikova, L. H.; Mulugeta, E.; de Almeida, S. F.; Muotri, A. R.; Heard, E.; Gendrel, A.-V.
10.1101/2024.02.20.581275 — genomics — Posted on 2024-02-20
1673 Retention of the full visual opsin repertoire in Australia's cryptozoic lizards
Ford, M. J. R.; Ludington, A. J.; Bradford, T.; Sanders, K. L.; Hutchinson, M. N.; Simoes, B. F.
10.1101/2024.02.19.581082 — molecular biology — Posted on 2024-02-20
1674 Fitness adaptations of Japanese encephalitis virus in pigs following vector-free serial passaging
Marti, A.; Nater, A.; Pego Magalhaes, J.; Almeida, L.; Lewandowska, M.; Liniger, M.; Ruggli, N.; Grau-Roma, L.; Alnaji, F.; Vignuzzi, M.; Garcia-Nicolas, O.; Summerfield, A.
10.1101/2024.02.20.581151 — microbiology — Posted on 2024-02-20
1675 Providing insight into the mechanism of action of Cationic Lipidated Oligomers (CLOs) using metabolomics
Hussein, M.; Mahboob, M. B.; Tait, J. R.; Grace, J. L.; Montembault, V.; Fontaine, L.; Quinn, J. F.; Velkov, T.; Whittaker, M. R.; Landersdorfer, C. B.
10.1101/2024.02.19.581110 — microbiology — Posted on 2024-02-20
1677 Characterisation and comparison of semen microbiota and sperm function in men with infertility, recurrent miscarriage, or proven fertility
Mowla, S.; Farahani, L.; Tharakan, T.; Davies, R.; Correia, G. D.; Lee, Y. S.; Kundu, S.; Khanjani, S.; Sindi, E.; Rai, R.; Regan, L.; Khalifa, D.; Henkel, R.; Minhas, S.; S. Dhillo, W.; Ben Nagi, J.; Bennett, P.; MacIntrye, D. A.; Jayasena, C. N.
10.1101/2024.02.18.580923 — microbiology — Posted on 2024-02-20
1681 Nasal commensals reduce Staphylococcus aureus proliferation by restricting siderophore availability
Zhao, Y.; Bitzer, A.; Power, J. J.; Belikova, D.; Torres-Salazar, B.; Adolf, L. A.; Gerlach, D.; Krismer, B.; Heilbronner, S.
10.1101/2024.02.20.581135 — microbiology — Posted on 2024-02-20
1683 Birnaviral Hijacking of Endosomal Membranes
Zanetti, F. A.; Fernandez, I.; Baquero, E.; Guardado-Calvo, P.; Dubois, S.; Morel, E.; Alfonso, V.; Aguilera, M. O.; Celayes, E. E.; Polo, L. M.; Suhaiman, L.; Galassi, V. V.; Chiarpotti, M. V.; Allende, C.; Rodriguez, J. M.; Caston, J. R.; Lijavetzky, D.; Taboga, O.; Colombo, M. I.; Del Popolo, M. G.; Rey, F. A.; Delgui, L. R.
10.1101/2024.02.20.581221 — microbiology — Posted on 2024-02-20
1684 Characterization of the SARS-CoV-2 BA.5 Variants in H11-K18-hACE2 Hamsters
Dong, M.; Lin, H.; Pan, M.; Huang, M.; Liu, M.; Jiang, R.; Lai, Y.; Shi, A.; Yao, B.; Hu, B.; Shi, Z.; Zhang, A.; Gao, Y.; Zeng, W.; Li, J.
10.1101/2024.02.19.581112 — immunology — Posted on 2024-02-20
1685 Prior exposure to malaria decreases SARS-CoV-2 mediated mortality in K18-hACE2 mice without influencing viral load in lungs
Mawatwal, S.; Mohapatra, A.; Das, S.; Ray, A.; Mukherjee, R.; Syed, G. H.; Senapati, S.; Ravindran, B.
10.1101/2024.02.19.579434 — immunology — Posted on 2024-02-20
1688 Electrode sharpness and insertion speed reduce tissue damage near high-density penetrating arrays
McNamara, I. N.; Wellman, S. M.; Li, L.; Eles, J. R.; Savya, S.; Sohal, H.; Angle, M.; Kozai, T. D. Y.
10.1101/2023.11.22.568119 — bioengineering — Posted on 2024-02-20
1690 The Alk receptor tyrosine kinase regulates Sparkly, a novel activity regulating neuropeptide precursor in the Drosophila CNS.
Sukumar, S. K.; Antonydhason, V.; Molander, L.; Sandakly, J.; Kleit, M.; Umapathy, G.; Mendoza-Garcia, P.; Masudi, T.; Schlosser, A.; Nassel, D. R.; Wegener, C.; Shirinian, M.; Palmer, R.
10.1101/2023.06.02.543395 — developmental biology — Posted on 2024-02-20
1691 Gut microbiota-derived gamma-aminobutyric acid from metformin treatment reduces hepatic ischemia/reperfusion injury through inhibiting ferroptosis
Wang, F.; Liu, X.; Huang, F.; Zhou, Y.; Wang, X.; Song, Z.; Wang, S.; Wang, X.; Shi, D.; Ruan, G.; Ji, X.; Zhang, E.; Tan, Z.; Ye, Y.; Wang, C.; Zhu, J.; Wang, W.
10.1101/2023.06.02.543432 — microbiology — Posted on 2024-02-20
1692 A Genome-Wide Arrayed CRISPR Screen Reveals PLSCR1 as an Intrinsic Barrier to SARS-CoV-2 Entry
Le Pen, J.; Paniccia, G.; Bauer, M.; Hoffmann, H.- H.; Kinast, V.; Moncada-Velez, M.; Pinharanda, A.; Ricardo-Lax, I.; Stenzel, A. F.; Rosado-Olivieri, E. A.; Ashbrook, A. W.; Dinnon, K. H.; Doyle, W.; Freije, C.; Hong, S.-H.; Lee, D.; Lewy, T.; Luna, J. M.; Peace, A.; Schmidt, C.; Schneider, W. M.; Winkler, R.; Larson, C.; McGinn, T.; Menezes, M.-R.; Ramos-Espiritu, L.; Banerjee, P.; Poirier, J. T.; Sanchez-Rivera, F. J.; Zhang, Q.; Casanova, J.-L.; Carroll, T. S.; Glickman, J. F.; Michailidis, E.; Razooky, B.; MacDonald, M. R.; Rice, C. M.
10.1101/2024.02.16.580725 — immunology — Posted on 2024-02-20
1694 Cortical gene expression architecture links healthy neurodevelopment to the imaging, transcriptomics, and genetics of autism and schizophrenia
Dear, R.; Wagstyl, K.; Seidlitz, J.; Markello, R. D.; Arnatkeviciute, A.; Anderson, K. M.; Bethlehem, R. A. I.; Lifespan Brain Chart Consortium, ; Raznahan, A.; Bullmore, E. T.; Vertes, P.
10.1101/2022.10.05.510582 — neuroscience — Posted on 2024-02-20
1702 Direct modulation of TRPM8 ion channels by rapamycin and analog macrolide immunosuppressants
Toth, B. I.; Bazeli, B.; Janssens, A.; Lisztes, E.; Racsko, M.; Kelemen, B.; Herczeg, M.; Nagy, T. M.; E. Köver, K.; Mitra, A.; Borics, A.; Biro, T.; Voets, T.
10.1101/2024.02.01.578392 — neuroscience — Posted on 2024-02-20
1703 Dysregulation of mitochondrial function by PLK1-mediated PDHA1 phosphorylation promotes Cr(VI)-associated lung cancer progression
ZHANG, Q.; Li, Z.; Rao, X.; Allison, D. B.; Qiao, Q.; Zhang, Z.; Kong, Y.; Zhang, Y.; Wang, R.; Liu, J.; Wang, X.; Li, C.; Mao, F.; Katz, W.; Shao, Q.; Gao, T.; Liu, X.
10.1101/2024.02.16.580630 — cancer biology — Posted on 2024-02-20
1705 The interactive effect of sustained sleep restriction and resistance exercise on skeletal muscle transcriptomics in young females
Knowles, O. E.; Soria, M.; Saner, N. J.; Trewin, A. J.; Alexander, S. E.; Roberts, S. S.; Hiam, D.; Garnham, A.; Drinkwater, E. J.; Aisbett, B.; Lamon, S.
10.1101/2024.02.15.580577 — genomics — Posted on 2024-02-20
1706 A multidimensional investigation of sleep and biopsychosocial profiles with associated neural signatures
Perrault, A. A.; Kebets, V.; Kuek, N. M. Y.; Cross, N. E.; Tesfaye, R.; Pomares, F. B.; Li, J.; Chee, M. W. L.; Dang Vu, T. T.; Yeo, B. T. T.
10.1101/2024.02.15.580583 — neuroscience — Posted on 2024-02-20
1709 Early-life exposures to specific commensal microbes prevent type 1 diabetes.
Green, J.; Deschaine, J.; Lubin, J.-B.; Flores, J. N.; Maddux, S.; Duranova, T.; Grimes, L.; Planet, P. J.; Eisenlohr, L. C.; Silverman, M. A.
10.1101/2024.02.15.580579 — immunology — Posted on 2024-02-20
1710 Theta-burst direct electrical stimulation remodels human brain networks
Huang, Y.; Zelmann, R.; Hadar, P.; Dezha-Peralta, J.; Richardson, M.; Williams, Z. M.; Cash, S. S.; Keller, C.; Paulk, A. C.
10.1101/2024.02.15.580568 — neuroscience — Posted on 2024-02-20
1711 Generalizable Neural Models of Emotional Engagement and Disengagement
Nanni Zepeda, M.; Evans, T.; Jagger-Rickels, A.; Raz, G.; Hendler, T.; Fan, Y.; Grimm, S.; Walter, M.; Esterman, M.; Zuberer, A.
10.1101/2024.02.15.579332 — neuroscience — Posted on 2024-02-20
1712 Multimodal classification of neurons in the lateral septum
Reid, C. M.; Ren, Y.; Xie, Y.; Turrero Garcia, M.; Tran, D.; Vu, S.; Liu, J.; Adam, M. A.; Hanson, S.; Pisco, A. O.; Harwell, C.
10.1101/2024.02.15.580381 — neuroscience — Posted on 2024-02-20
1713 Healthy dietary choices involve prefrontal mechanisms associated with long-term reward maximization but not cognitive control
Takehana, A.; Tanaka, D.; Arai, M.; Hattori, Y.; Yoshimoto, T.; Matsui, T.; Sadato, N.; Chikazoe, J.; Jimura, K.
10.1101/2024.02.15.580403 — neuroscience — Posted on 2024-02-20
1715 Tuning a mechanical model to biological reality: A case study in the LaMSA system of the trap-jaw ant Strumigenys
Anderson, P. S. L.; Jorge, J. F.; Crofts, S. B.; Castro, J. T.; Didcock, R. L.; Cook, A.; Larabee, F. J.; Ilton, M.
10.1101/2024.02.15.580213 — biophysics — Posted on 2024-02-20
1716 Asymmetric Fin Shape changes Swimming Dynamics of Ancient Marine Reptiles' Soft Robophysical Models
Sprumont, H.; Allione, F.; Schwab, F.; Wang, B.; Mucingat, C.; Lunati, I.; Scheyer, T.; Ijspeert, A.; Jusufi, A.
10.1101/2024.02.15.580532 — biophysics — Posted on 2024-02-20
1719 A low-abundance class of Dicer-dependent siRNAs produced from a variety of features in C. elegans
Knittel, T. L.; Montgomery, B. E.; Tate, A. J.; Deihl, E. W.; Nawrocki, A. S.; Hoerndli, F. J.; Montgomery, T. A.
10.1101/2024.02.15.580610 — genomics — Posted on 2024-02-20
1722 Tissue damage during acute Trypanosoma cruzi infection is associated with reduced reparative regulatory T cell response and can be attenuated by early interleukin-33 administration.
Boccardo, S.; Rodriguez, C.; Furlan, C. L. A.; Abrate, C. P.; Almada, L.; Gimenez, C. M.; Concepcion, M. A. S.; Skewes-Cox, P.; Rao, S. P. S.; Montes, C. L.; Gruppi, A.; Rodriguez, E. V. A.
10.1101/2024.02.15.580513 — immunology — Posted on 2024-02-20
1723 Cellular mechanisms underlying beneficial versus detrimental effects of bacterial antitumor immunotherapy
Castillo, J. G.; Fernandez, S.; Campbell, T.; Williams, J.; Gonzalez-Ventura, D.; Ybarra, J.; Hernandez, N. F.; Wells, E.; Portnoy, D. A.; DuPage, M.
10.1101/2024.02.15.580555 — immunology — Posted on 2024-02-20
1725 Neurovascular mitochondrial susceptibility impacts blood-brain barrier function and behavior
Crockett, A. M.; Kebir, H.; Velez-Colon, M. C.; Iascone, D. M.; Cielieski, B.; Rossano, A.; Sehgal, A.; Anderson, S. A.; Alvarez, J. I.
10.1101/2024.02.15.580544 — neuroscience — Posted on 2024-02-20
1728 Non-canonical Metabolic and Molecular Effects of Calorie Restriction Are Revealed by Varying Temporal Conditions
Pak, H. H.; Grossberg, A. N.; Sanderfoot, R. R.; Babygirija, R.; Green, C. L.; Koller, M. J.; Dzieciatkowska, M.; Paredes, D. A.; Lamming, D. W.
10.1101/2024.02.15.580502 — physiology — Posted on 2024-02-20
1729 Chemical genetics in C. elegans identifies anticancer mycotoxins chaetocin and chetomin as potent inducers of a nuclear metal homeostasis response
Abraham, E.; Athapaththu, A. M. G. K.; Atanasova, K. R.; Chen, Q.-Y.; Corcoran, T. J.; Piloto, J.; Wu, C.-W.; Ratnayake, R.; Luesch, H.; Choe, K. P.
10.1101/2024.02.15.579914 — pharmacology and toxicology — Posted on 2024-02-20
1731 The transcription factor RIP140 regulates interferon γ signaling in breast cancer
Jalaguier, S.; Kuehn, A.; Petitpas, C.; Dulom, A.; Jacquemont, R.; Assi, C.; Sixou, S.; Jeschke, U.; Colinge, J.; Cavailles, V.
10.1101/2024.02.15.580503 — cancer biology — Posted on 2024-02-20
1736 Performance of GPT-4 on the American College of Radiology In-Service Examination
Payne, D. L.; Purohit, K.; Borrero, W. M.; Chung, K.; Hao, M.; Mpoy, M.; Jin, M.; Prasanna, P.; Hill, V.
10.1101/2024.02.15.580546 — bioinformatics — Posted on 2024-02-20
1737 Integrated Short-TE and Hadamard-edited Multi-Sequence (ISTHMUS) for Advanced MRS
Hui, S. C. N.; Murali-Manohar, S.; Zollner, H. J.; Hupfeld, K. E.; Davies-Jenkins, C. W.; Gudmundson, A. T.; Song, Y.; Yedavalli, V.; Wisnowski, J. L.; Gagoski, B.; Oeltzschner, G.; Edden, R. A. E.
10.1101/2024.02.15.580516 — bioengineering — Posted on 2024-02-20
1740 SCRAPPY - a single cell rapid assay of proteome perturbation in yeast uncovers a joint role of aromatic amino acids and oxidative stress in the toxicity of lipophilic nucleoside analogs
Ghazy, E.; Bidiuk, V. A.; Ryabov, F.; Mitkevich, O. V.; Riabova, O.; Stanishevskiy, Y. M.; Levshin, I. B.; Alexandrova, L. A.; Jasko, M. V.; Makarov, D. A.; Zhgun, A. A.; Avdanina, D. A.; Ermolyuk, A. A.; Kushnirov, V. V.; Egorova, A. P.; Agaphonov, M. O.; Alexandrov, A. I.
10.1101/2024.02.19.580949 — microbiology — Posted on 2024-02-20
1741 Non-Hebbian plasticity transforms transient experiences into lasting memories
Faress, I.; Khalil, V.; Hou, W.-H.; Moreno, A.; Andersen, N.; Fonseca, R.; Piriz, J.; Capogna, M.; Nabavi, S.
10.1101/2023.04.06.535862 — neuroscience — Posted on 2024-02-20
1742 Rapid modeling of an ultra-rare epilepsy patient variant in mice by in utero prime editing
Robertson, C. D.; Davis, P.; Richardson, R. R.; Iffland, P. H.; Vieira, D. C. O.; Steyert, M.; McKeon, P. N.; Romanowski, A. J.; Crutcher, G.; Jasarevic, E.; Wolff, S. B. E.; Mathur, B. N.; Crino, P. B.; Bale, T. L.; Dick, I. E.; Poulopoulos, A.
10.1101/2023.12.06.570164 — neuroscience — Posted on 2024-02-20
1744 Molecular response to multiple trace-element contamination of the European sardine
Beauvieux, A.; Fromentin, J.-M.; Saraux, C.; Romero, D.; Couffin, N.; Brown, A.; Metral, L.; Bertile, F.; Schull, Q.
10.1101/2024.02.16.580673 — physiology — Posted on 2024-02-20
1747 Structural perspective on the design of selective DYRK1B inhibitors
Grygier, P.; Pustelny, K.; Menezes, F.; Jemiola-Rzeminska, M.; Suder, P.; Dubin, G.; Czarna, A.
10.1101/2022.12.23.521429 — biochemistry — Posted on 2024-02-20
1748 Estimation of contemporary effective population size in plant populations: limitations of genomic datasets
Gargiulo, R.; Decroocq, V.; Gonzalez-Martinez, S. C.; Paz-Vinas, I.; Aury, J.-M.; Lesur Kupin, I.; Plomion, C.; Schmitt, S.; Scotti, I.; Heuertz, M.
10.1101/2023.07.18.549323 — evolutionary biology — Posted on 2024-02-20
1749 The olivary input to the cerebellum dissociates sensory events from movement plans
Pi, J. S.; Fakharian, M. A.; Hage, P.; Sedaghat-Nejad, E.; Muller, S. Z.; Shadmehr, R.
10.1101/2022.07.11.499614 — neuroscience — Posted on 2024-02-20
1750 Active learning of enhancer and silencer regulatory grammar in a developing neural tissue
Friedman, R. Z.; Ramu, A.; Lichtarge, S.; Wu, Y.; Tripp, L.; Lyon, D.; Myers, C. A.; Granas, D. M.; Gause, M.; Corbo, J. C.; Cohen, B. A.; White, M. A.
10.1101/2023.08.21.554146 — genomics — Posted on 2024-02-20
1751 An optimised protocol for quality control of gene therapy vectors using Nanopore direct RNA sequencing
Zeglinski, K.; Montellese, C.; Ritchie, M. E.; Alhamdoosh, M.; Vonarburg, C.; Bowden, R.; Jordi, M.; Gouil, Q.; Aeschimann, F.; Hsu, A.
10.1101/2023.12.03.569756 — genomics — Posted on 2024-02-20
1756 PURA Syndrome-causing mutations impair PUR-domain integrity and affect P-body association
Proske, M.; Janowski, R.; Bacher, S.; Kang, H.-S.; Monecke, T.; Koehler, T.; Hutten, S.; Tretter, J.; Crois, A.; Molitor, L.; Varela-Rial, A.; Fino, R.; Donati, E.; De Fabritiis, G.; Dormann, D.; Sattler, M.; Niessing, D.
10.1101/2023.09.19.558386 — molecular biology — Posted on 2024-02-20
1757 Anti-capsule human monoclonal antibodies protect against hypervirulent and pandrug-resistant Klebsiella pneumoniae
Roscioli, E.; Zucconi Galli Fonseca, V.; Bosch, S. S.; Paciello, I.; Maccari, G.; Batani, G.; Stazzoni, S.; Cardinali, G.; Tiseo, G.; Giordano, C.; Shen, Y.; Capoccia, L.; Ridelfi, M.; Troisi, M.; Manganaro, N.; Mugnaini, C.; Cardamone, D.; De Santi, C.; Ciabattini, A.; Cerofolini, L.; Fragai, M.; Licastro, D.; Nicolau, D. P.; Abdelraouf, K.; Barnini, S.; Menichetti, F.; Falcone, M.; Sala, C.; Kabanova, A.; Rappuoli, R.
10.1101/2024.02.14.580141 — microbiology — Posted on 2024-02-20
1758 A Plasmodium falciparum MORC protein complex modulates epigenetic control of gene expression through interaction with heterochromatin.
Singh, M. K.; Bonnell, V.; Silva, I.; Santiago, V. F.; Moraes, M.; Adderley, J.; Doerig, C.; Palmisano, G.; Llinas, M.; Garcia, C. R.
10.1101/2023.09.11.557196 — microbiology — Posted on 2024-02-20
1760 Personalized circuit modeling captures variation in cortical functional connectivity
Cooper, R. A.; Demirtas, M.; Burt, J. B.; Howell, A. M.; Ji, J. L.; Repovs, G.; Sotiropoulos, S.; Anticevic, A.; Murray, J. D.
10.1101/2024.02.19.581085 — neuroscience — Posted on 2024-02-20
1762 Intrinsic structural covariation links cerebellum subregions to the cerebral cortex
Wang, Z.; Diedrichsen, J.; Saltoun, K.; Steele, C. J.; Arnold-Anteraper, S. R.; Yeo, B. T. T.; Schmahmann, J.; Bzdok, D.
10.1101/2024.02.16.580701 — neuroscience — Posted on 2024-02-20
1763 miR-100 and miR-125b Contribute to Enhanced 3D Growth and Invasiveness and can be Functionally Transferred to Silence Target Genes in Recipient Cells
Nelson, H. M.; Qu, S.; Chapman, S. N.; Luthcke, N. L.; Schuster, S. A.; Turnbull, L. A.; Shameer, M.; Guy, L. L.; Liu, X.; Corn, K. C.; Vickers, K. C.; Liu, Q.; Franklin, J. L.; Weaver, A.; Rafat, M.; Coffey, R. J.; Patton, J. G.
10.1101/2024.01.16.575716 — cancer biology — Posted on 2024-02-20
1764 Image processing tools for petabyte-scale light sheet microscopy data
Ruan, X.; Mueller, M.; Liu, G.; Görlitz, F.; Fu, T.-M.; Milkie, D. E.; Lillvis, J. L.; Kuhn, A.; Herr, C. Y. A.; Hercule, W.; Nienhaus, M.; Killilea, A. N.; Betzig, E.; Upadhyayula, S.
10.1101/2023.12.31.573734 — bioinformatics — Posted on 2024-02-20
1767 Engineering mice for female-biased progeny without impacting genetic integrity and litter size
Yosef, I.; Mahata, T.; Chen, Y.; Bar-Joseph, H.; Shalgi, R.; Munitz, A.; Gerlic, M.; Qimron, U.
10.1101/2023.11.21.568055 — bioengineering — Posted on 2024-02-20
1771 CXCL4 signaling and gene induction in human monocytes
YANG, C.; Yuan, R.; Mishra, B.; Bill, R. D.; Zhang, Y.; Du, Y.; Ah Kioon, M. D.; Barrat, F. J.; Ivashkiv, L. B.
10.1101/2022.10.26.513860 — immunology — Posted on 2024-02-20
1773 The gut lactic acid bacteria metabolite, 10-oxo-cis-6,trans-11-octadecadienoic acid, suppresses inflammatory bowel disease in mice by modulating the NRF2 pathway and GPCR-signaling
Ando, M.; Nagata, K.; Takeshita, R.; Ito, N.; Noguchi, S.; Minamikawa, N.; Kodama, N.; Yamamoto, A.; Yashiro, T.; Hachisu, M.; Ichihara, G.; Kishino, S.; Yamamoto, M.; Ogawa, J.; Nishiyama, C.
10.1101/2023.02.22.529495 — immunology — Posted on 2024-02-20
1774 Reconstructing Spatio-Temporal Trajectories of Visual Object Memories in the Human Brain
Lifanov, J.; Griffiths, B. J.; Linde-Domingo, J.; Ferreira, C. S.; Wilson, M.; Mayhew, S. D.; Charest, I.; Wimber, M.
10.1101/2022.12.15.520591 — neuroscience — Posted on 2024-02-20
1775 Aging drives cerebrovascular network remodeling and functional changes in the mouse brain
Bennett, H. C.; Zhang, Q.; Wu, Y.-t.; Manjila, S. B.; Chon, U.; Shin, D.; Vanselow, D. J.; Pi, H.-J.; Drew, P. J.; Kim, Y.
10.1101/2023.05.23.541998 — neuroscience — Posted on 2024-02-20
1777 Impaired updating of working memory representations in individuals with high BMI: evidence for dopaminergic mechanisms
Herzog, N.; Hartmann, H.; Janssen, L. K.; Kanyamibwa, A.; Waltmann, M.; Kovacs, P.; Deserno, L.; Fallon, S.; Villringer, A.; Horstmann, A.
10.1101/2023.11.03.565528 — neuroscience — Posted on 2024-02-20
1780 Rejuvenation of Senescent Cells by Low Frequency Ultrasound without Senolysis
Kureel, S. K.; Maroto, R.; Powell, S.; Margadant, F.; Blair, B.; Rasmussen, B.; Sheetz, M.
10.1101/2022.12.08.519320 — physiology — Posted on 2024-02-20
1781 Brain-Derived CCN3 Is An Osteoanabolic Hormone That Sustains Bone in Lactating Females
Babey, M. E.; Krause, W. C.; Herber, C. B.; Chen, K.; Torok, Z.; Nikkannen, J.; Rodriquez, R.; Zhang, X.; Castro-Navarro, F.; Wang, Y.; Villeda, S.; Lane, N. E.; Scheller, E. L.; Chan, C. K. F.; Ambrosi, T. H.; Ingraham, H. A.
10.1101/2023.08.28.554707 — neuroscience — Posted on 2024-02-19
1782 Reconstructing prevalence dynamics of wildlife pathogens from pooled and individual samples
Borremans, B.; Falvo, C. A.; Crowley, D. E.; Hoegh, A.; Lloyd-Smith, J. O.; Peel, A. J.; Restif, O.; Ruiz-Aravena, M.; Plowright, R. K.
10.1101/2023.11.02.565200 — ecology — Posted on 2024-02-19
1783 Detecting superspreaders in wildlife reservoirs of disease
Konzen, E.; Delahay, R. J.; Hodgson, D. J.; McDonald, R. A.; Brooks Pollock, E.; Spencer, S. E. F.; McKinley, T. J.
10.1101/2024.01.26.576600 — ecology — Posted on 2024-02-19
1785 Genome assembly and genomic architecture of a prominent cold-resistant rapeseed germplasm
Wu, Z.; Zheng, G.; Sun, Y.; Dong, X.; Wang, Y.; Li, H.; Niu, Y.; Huang, Z.; Hu, J.; Liu, Z.
10.1101/2023.11.12.566742 — genomics — Posted on 2024-02-19
1786 The ivory lncRNA regulates seasonal color patterns in buckeye butterflies
Fandino, R. A.; Brady, N. K.; Chatterjee, M.; McDonald, J. M. C.; Livraghi, L.; van der burg, K.; Mazo-Vargas, A.; Markenscoff-Papadimitriou, E.; Reed, R. D.
10.1101/2024.02.09.579733 — genetics — Posted on 2024-02-19
1787 Cooperativity and additivity in plant enhancers
Jores, T.; Tonnies, J.; Mueth, N. A.; Romanowski, A.; Fields, S.; Cuperus, J.; Queitsch, C.
10.1101/2023.11.21.568158 — plant biology — Posted on 2024-02-19
1788 Altered NRG1/ErbB4 signaling and cholesterol metabolism dysregulation are key pathomechanisms in VRK1-related motor neuropathies and motor neuron diseases
Hamze, Z.; Humbert, C.; Rihan, K.; Roeckel-Trevisiol, N.; Castro, C.; Lenfant, N.; Robert, C.; Bertaux, K.; Jabbour, R.; Bernard-Marissal, N.; Megarbane, A.; DELAGUE, V.
10.1101/2024.02.19.581053 — genetics — Posted on 2024-02-19
1791 Natural Variation in Age-Related Dopamine Neuron Degeneration is Glutathione-Dependent and Linked to Life Span
Coleman, C. R.; Pallos, J.; Arreola-Bustos, A.; Wang, L.; Raftery, D.; Promislow, D. E. L.; Martin, I.
10.1101/2024.02.12.580013 — neuroscience — Posted on 2024-02-19
1792 Neural circuit models for evidence accumulation through choice-selective sequences
Brown, L. S.; Cho, J. R.; Bolkan, S. S.; Nieh, E. H.; Schottdorf, M.; Tank, D. W.; Brody, C. D.; Witten, I. B.; Goldman, M. S.
10.1101/2023.09.01.555612 — neuroscience — Posted on 2024-02-19
1794 Site-specific Effector Protein Functionalization to Create Bead-based Avidity Model Systems
Hackl, M.; Jayachandran, D.; Ramdin, K.; Zhong, T.; Travers, T.; Gnanakaran, S.; Chundawat, S. P. S.
10.1101/2023.03.27.534459 — bioengineering — Posted on 2024-02-19
1796 Discovery of Alkenyl Oxindole as a Novel PROTAC Moiety for Targeted Protein Degradation via CRL4DCAF11 Recruitment
Wang, Y.; Wei, T.; Zhao, M.; Huang, A.; Sun, F.; Chen, L.; Lin, R.; Xie, Y.; Zhang, M.; Xu, S.; Sun, Z.; Hong, L.; Wang, R.; Tian, R.; Li, G.
10.1101/2024.02.15.580430 — biochemistry — Posted on 2024-02-19
1797 Dynamics of interdomain rotation facilitates FtsZ filament assembly
Chakraborty, J.; Poddar, S. M.; Dutta, S.; Bahulekar, V.; Harne, S.; SRINIVASAN, R.; Gayathri, P.
10.1101/2022.10.13.512043 — biochemistry — Posted on 2024-02-19
1803 Tetrameric INTS6-SOSS1 complex facilitates DNA:RNA hybrid autoregulation at double-strand breaks
Long, Q.; Ajit, K.; Sedova, K.; Haluza, V.; Stefl, R.; Dokaneheifard, S.; Beckedorff, F.; Valencia, M. G.; Sebesta, M.; Shiekhattar, R.; Gullerova, M.
10.1101/2024.02.19.580984 — molecular biology — Posted on 2024-02-19
1804 Activation of Macrophages by Extracellular Vesicles Derived from Babesia-infected Red Blood Cells
Hagos, B.; Brasov, I.; Branscome, H.; Kashanchi, F.; Ben Mamoun, C.; Molestina, R. E.
10.1101/2024.02.19.581030 — microbiology — Posted on 2024-02-19
1805 Glutathione metabolism impacts fungal virulence by modulating the redox environment
Black, B.; Roque da Silva, L. B.; Hu, G.; Qu, X.; Smith, D. F.; Magana, A. A.; Horianopoulos, L. C.; Caza, M.; Attarian, R.; Foster, L. J.; Casadevall, A.; Kronstad, J. W.
10.1101/2024.02.19.581054 — microbiology — Posted on 2024-02-19
1807 Hippocampal reactive neural stem cells are able to phagocytose and have an immunological molecular signature
Abiega, O.; Senovilla-Ganzo, R.; El-Ouraoui, M.; Muro Garcia, T.; Ruiz Clavijo, L.; Garcia Moreno, F.; Fitzsimons, C. P.; Martin Suarez, S.; Encinas Perez, J. M.
10.1101/2024.01.26.577346 — neuroscience — Posted on 2024-02-19
1808 Chloroplast Cell-Free Systems from Different Plant Species as a Rapid Prototyping Platform
Boehm, C. V.; Inckemann, R.; Burgis, M.; Baumann, J.; Brinkmann, C. K.; Lipinska, K. E.; Gilles, S.; Freudigmann, J.; Seiler, V.; Clark, L. G.; Jewett, M. C.; Voll, L. M.; Niederholtmeyer, H.
10.1101/2024.02.19.580994 — synthetic biology — Posted on 2024-02-19
1810 PKR activation-induced mitochondrial dysfunction in HIV-transgenic mice with nephropathy
Yoshida, T.; Latt, K. Z.; Rosenberg, A. Z.; Santo, B. A.; Myakala, K.; Ishimoto, Y.; Zhao, Y.; Shrivastav, S.; Jones, B. A.; Yang, X.; Wang, X.; Tutino, V. M.; Sarder, P.; Levi, M.; Okamoto, K.; Winkler, C. A.; Kopp, J. B.
10.1101/2022.10.03.510678 — pathology — Posted on 2024-02-19
1813 Design and optimization of silicon-based electrokinetic microchip for sensitive detection of small extracellular vesicles
Talebian Gevari, M.; Sahu, S. S.; Stridfeldt, F.; Haag, P.; Viktorsson, K.; Lewensohn, R.; Gori, A.; Cretich, M.; Dev, A.
10.1101/2022.08.17.504250 — bioengineering — Posted on 2024-02-19
1818 Clonal analysis of fetal hematopoietic stem/progenitor cell subsets reveals how post-transplantation capabilities are distributed
Stonehouse, O.; Biben, C.; Weber, T. S.; Garnham, A.; Fennell, K.; Farley, A.; Terreaux, A.; Alexander, W.; Dawson, M.; Naik, S.; Taoudi, S.
10.1101/2024.02.19.579920 — developmental biology — Posted on 2024-02-19
1820 To 200,000 m/z and beyond: native electron capture charge reduction mass spectrometry deconvolves heterogeneous signals in large biopharmaceutical analytes
Le Huray, K. I. P.; Woerner, T. P.; Moreira, T.; Reinhardt-Szyba, M.; Devine, P. W. A.; Bond, N. J.; Fort, K. L.; Makarov, A. A.; Sobott, F.
10.1101/2024.02.19.581059 — molecular biology — Posted on 2024-02-19
1823 RfaA (YqhY), a novel adaptor protein, controls metabolite-sensitive protein degradation in Bacillus subtilis
Wicke, D.; Lentes, S.; Herrfurth, C.; Toedter, D.; Stannek-Goebel, L.; Commichau, F. M.; Feussner, I.; Stulke, J.
10.1101/2024.02.19.580884 — microbiology — Posted on 2024-02-19
1825 Discovering and exploring the hidden diversity of human gut viruses using highly enriched virome samples
Zolfo, M.; Silverj, A.; Blanco-Miguez, A.; Manghi, P.; Rota-Stabelli, O.; Heidrich, V.; Jensen, J.; Maharjan, S.; Franzosa, E.; Menni, C.; Visconti, A.; Pinto, F.; Ciciani, M.; Huttenhower, C.; Cereseto, A.; Asnicar, F.; Kitano, H.; Yamada, T.; Segata, N.
10.1101/2024.02.19.580813 — microbiology — Posted on 2024-02-19
1826 Journey to the center of the phage; revealing the ejectosome of Pectobacterium bacteriophage {Phi}M1
Eruera, A.-R.; Hodgkinson-Bean, J.; Rutter, G. L.; Hills, F. R.; Kumaran, R.; Crowe, A. J. M.; Jadav, N.; McJarrow-Keller, K. L.; Jorge, F. E.; Hyun, J.; Kim, H.; Ryu, B.; Bostina, M.
10.1101/2024.02.19.577657 — microbiology — Posted on 2024-02-19
1829 Structural basis of Ebola virus nucleocapsid assembly and functions
Fujita-Fujiharu, Y.; Hu, S.; Hirabayashi, A.; Takamatsu, Y.; Ng, Y. N.; Houri, K.; Muramoto, Y.; Nakano, M.; Sugita, Y.; Noda, T.
10.1101/2024.02.19.580633 — microbiology — Posted on 2024-02-19
1831 Mod5 mediates a molecular trade-off between optimal gene expression and antifungal resistance.
Bruch, A.; Lazarova, V.; Krueger, T.; Schaeuble, S.; Kelani, A. A.; Lehenberger, P.; Kniemeyer, O.; Panagiotou, G.; Blango, M. G.
10.1101/2024.02.19.578369 — microbiology — Posted on 2024-02-19
1832 Robust SARS-CoV-2 Neutralizing Antibodies Sustained through Three Months Post XBB.1.5 mRNA Vaccine Booster
Wang, Q.; Mellis, I. A.; Guo, Y.; Gherasim, C.; Valdez, R.; Gordon, A.; Liu, L.; Ho, D. D.
10.1101/2024.02.16.580687 — immunology — Posted on 2024-02-19
1834 A temperature-inducible protein module for control of mammalian cell fate
Benman, W.; Huang, Z. D.; Iyengar, P.; Wilde, D.; Mumford, T.; Bugaj, L.
10.1101/2024.02.19.581019 — synthetic biology — Posted on 2024-02-19
1835 COVID-19 during pregnancy alters circulating extracellular vesicle cargo and their effects on trophoblast
Golden, T. N.; Mani, S.; Anton, L.; Conine, C. C.; Linn, R. L.; Leite, R.; Kaufman, B. A.; Mainigi, M.; Trigg, N. A.; Wilson, A.; Strauss, J. F.; Parry, S.; Simmons, R. A.
10.1101/2024.02.17.580824 — pathology — Posted on 2024-02-19
1836 A Genome-Wide Arrayed CRISPR Screen Reveals PLSCR1 as an Intrinsic Barrier to SARS-CoV-2 Entry
Le Pen, J.; Paniccia, G.; Bauer, M.; Hoffmann, H.- H.; Kinast, V.; Moncada-Velez, M.; Pinharanda, A.; Ricardo-Lax, I.; Stenzel, A. F.; Rosado-Olivieri, E. A.; Ashbrook, A. W.; Dinnon, K. H.; Doyle, W.; Freije, C.; Hong, S.-H.; Lee, D.; Lewy, T.; Luna, J. M.; Peace, A.; Schmidt, C.; Schneider, W. M.; Winkler, R.; Larson, C.; McGinn, T.; Menezes, M.-R.; Ramos-Espiritu, L.; Banerjee, P.; Poirier, J. T.; Sanchez-Rivera, F. J.; Zhang, Q.; Casanova, J.-L.; Carroll, T. S.; Glickman, J. F.; Michailidis, E.; Razooky, B.; MacDonald, M. R.; Rice, C. M.
10.1101/2024.02.16.580725 — immunology — Posted on 2024-02-19
1837 Stability from subspace rotations and traveling waves
Batabyal, T.; Brincat, S. L.; Donoghue, J. A.; Lundqvist, M.; Mahnke, M. K.; Miller, E. K.
10.1101/2024.02.19.581020 — neuroscience — Posted on 2024-02-19
1838 Mechanical convergence in mixed populations of mammalian epithelial cell
Gauquelin, E.; Kuromiya, K.; Namba, T.; Ikawa, K.; Fujita, Y.; Ishihara, S.; Sugimura, K.
10.1101/2024.02.18.580863 — cell biology — Posted on 2024-02-19
1840 EGF/STAT1 signals to maintain ECM1 expression in hepatic homeostasis are disrupted by IFNγ/NRF2 in chronic liver disease
Li, Y.; Link, F.; Fan, W.; Nwosu, Z. C.; Pioronska, W.; Gould, K.; Meyer, C.; Yao, Y.; Hammad, S.; Feng, R.; Liu, H.; Shao, C.; Sun, B.; Ding, H.; Liebe, R.; Ebert, M. P. A.; Weng, H.-L.; ten Dijke, P.; Dooley, S.; Wang, S.
10.1101/2024.02.17.580798 — cell biology — Posted on 2024-02-19
1842 Sildenafil amplifies calcium influx and insulin secretion in pancreatic β cells
Murao, N.; Morikawa, R.; Seino, Y.; Shimomura, K.; Maejima, Y.; Yamada, Y.; Suzuki, A.
10.1101/2024.02.17.580848 — cell biology — Posted on 2024-02-19
1845 Inhibition of Soluble Epoxide Hydrolase Reduces Inflammation and Myocardial Injury in Arrhythmogenic Cardiomyopathy
Panigrahy, D.; Kelly, A.; Wang, W.; Yang, J.; Hwang, S. H.; Gillespie, M.; Howard, I.; Bueno-Beti, C.; Asimaki, A.; Penna, V.; Lavine, K.; Edin, M.; Zeldin, D.; Hammock, B.; Saffitz, J.
10.1101/2024.02.17.580812 — cell biology — Posted on 2024-02-19
1846 Expression of Plasmodium Major Facilitator Superfamily Protein in Transporters-Delta Candida Identifies a Drug Transporter
Maurya, P.; Kumar, M.; Jain, R.; Singh, H.; Thaer Abdulhameed Almuqdadi, H.; Gupta, A.; Arenz, C.; Gaur, N.; Singh, S.
10.1101/2024.02.18.580920 — cell biology — Posted on 2024-02-19
1847 Biogenic nanoparticles from liquid and solid matrices: biochemical and biophysical properties of Extracellular Vesicles-enriched samples from human plasma and skeletal muscle tissue.
Mangolini, V.; Radeghieri, A.; Piva, S.; Cattaneo, S.; Brucale, M.; Valle, F.; Balestri, A.; Montis, C.; Latronico, N.; Bergese, P.; Paolini, L.
10.1101/2024.02.19.580950 — cell biology — Posted on 2024-02-19
1849 Large-scale visualisation of α-synuclein oligomers in Parkinson's disease brain tissue
Andrews, R.; Fu, B.; Toomey, C. E.; Breiter, J. C.; Lachica, J.; Tian, R.; Beckwith, J. S.; Needham, L.-M.; Chant, G. J.; Loiseau, C.; Deconfin, A.; Baspin, K.; Magill, P. J.; Jaunmuktane, Z.; Freeman, O. J.; Taylor, B. J. M.; Hardy, J.; Lashley, T.; Ryten, M.; Vendruscolo, M.; Wood, N. W.; Weiss, L. E.; Gandhi, S.; Lee, S. F.
10.1101/2024.02.17.580698 — neuroscience — Posted on 2024-02-19
1850 Novel therapies for cancer-induced bone pain
Haroun, R.; Gossage, S. J.; Iseppon, F.; Fudge, A.; Caxaria, S.; Arcangeletti, M.; Leese, C.; Davletov, B.; Cox, J. J.; Sikandar, S.; Welsh, F.; Chessell, I. P.; Wood, J.
10.1101/2024.02.19.580951 — neuroscience — Posted on 2024-02-19
1854 Patient-derived functional immuno-oncology platform identifies responders to ATR inhibitor and immunotherapy combinations in ovarian cancer
Nagaraj, A. S.; Salko, M.; Sirsikar, A.; Erkan, E. P.; Pietilä, E. A.; Niemiec, I.; Bao, J.; Marchi, G.; Szabo, A.; Nowlan, K.; Pikkusaari, S.; Kanerva, A.; Tapper, J.; Koivisto-Korander, R.; Kauppi, L.; Hautaniemi, S.; Vähärautio, A.; Tang, J.; Haltia, U.-M.; Kekäläinen, E.; Virtanen, A.; Salo, T.; Färkkilä, A.
10.1101/2024.02.15.579904 — cancer biology — Posted on 2024-02-19
1855 Single nuclei and spatial transcriptomes suggest a stratification of papillary and anaplastic thyroid cancer cells
Tourneur, A.; Rodrigues Vitoria, J.; Saiselet, M.; Craciun, L.; Larsimont, D.; Lefort, A.; Libert, F.; Maenhaut, C.; Costagliola, S.; Tarabichi, M.; Romitti, M.; Detours, V.
10.1101/2024.02.15.580495 — cancer biology — Posted on 2024-02-19
1856 Probing drug-target engagement of soluble Gαi1 protein using the SolThermoBRET thermal shift assay
Brod, O.; Plevako, D.; Perera, T.; Hompluem, P.; Koers, E. J.; Hilbert, M.; Sykes, D. A.; Veprintsev, D.
10.1101/2024.02.15.580002 — biophysics — Posted on 2024-02-19
1858 Molecular chaperone BiP controls activity of the ER stress sensor Ire1 through interactions with its oligomers
Dawes, S.; Hurst, N.; Grey, G.; Wieteska, L.; Wright, N. V.; Manfield, I. W.; Hussain, M. H.; Kalverda, A. P.; Lewandowski, J. R.; Chen, B.; Zhuravleva, A.
10.1101/2024.02.16.579620 — biophysics — Posted on 2024-02-19
1860 Tracing the evolutionary history of Tunisian HPV 16 and 18 across the genetic diversity in L1 gene
Ardhaoui, M.; Dekhil, N.; Bouslama, Z.; Bel Hadj Rhouma, R.; Fehri, E.; Ennaifer, E.; Guizani, I.
10.1101/2024.02.15.580472 — evolutionary biology — Posted on 2024-02-19
1862 Metformin Enhances Antibody-Mediated Recognition of HIV-Infected CD4+ T-Cells by Decreasing Viral Release
Fert, A.; Richard, J.; Raymond Marchand, L.; Planas, D.; Routy, J.-P.; Chomont, N.; Finzi, A.; Ancuta, P.
10.1101/2024.02.15.580166 — immunology — Posted on 2024-02-19
1863 Brainwide mesoscale functional networks revealed by focal infrared neural stimulation of the amygdala
Ping, A.; Wang, J.; Garcia Cabezas, M. A.; Li, L.; Zhang, J.; Zhu, J.; Gothard, K. M.; Roe, A. W.
10.1101/2024.02.14.580397 — neuroscience — Posted on 2024-02-19
1864 Brain substates induced by DMT relate to sympathetic output and meaningfulness of the experience
Pasquini, L.; Simon, A.; Gallen, C.; Kettner, H.; Roseman, L.; Gazzaley, A.; Carhart-Harris, R.; Timmermann, C.
10.1101/2024.02.14.580356 — neuroscience — Posted on 2024-02-19
1865 Sympathetic Signals Promote Immunosuppressive Neutrophils in Lung Tumors
Liu, J.; Qiu, M.; Wang, W.; Cao, Y.; Yang, F.; Chen, K.; Chen, J.; Yang, J.
10.1101/2024.02.15.580434 — neuroscience — Posted on 2024-02-19
1868 Morphing Cholinesterase Inhibitor Amiridine into Multipotent Drugs for the Treatment of Alzheimer's Disease
Mezeiova, E.; Prchal, L.; Hrabinova, M.; Muckova, L.; Pulkrabkova, L.; Soukup, O.; Misiachna, A.; Janousek, J.; Fibigar, J.; Kucera, T.; Horak, M.; Makhaeva, G. F.; Korabecny, J.
10.1101/2024.02.15.580468 — neuroscience — Posted on 2024-02-19
1871 Vaginal lactobacilli produce anti-inflammatory beta-carboline compounds.
Webber, C. A.; Glick, V. J.; Martin, M.; Kim, C.; Ahmad, M.; Simmons, L. E.; Bang, S.; Chao, M. C.; Howard, N. C.; Fortune, S. M.; Beura, L. K.; Lee, S. Y.; Clardy, J.; Kim, K. H.; Gopinath, S.
10.1101/2024.02.19.580919 — microbiology — Posted on 2024-02-19
1873 Evaluating models of the ageing BOLD response
Henson, R. N.; Olszowy, W.; Tsvetanov, K. A.; Yadav, P. S.; CamCAN, ; Zeidman, P.
10.1101/2023.08.24.554634 — neuroscience — Posted on 2024-02-19
1874 New observations of fluorescent organisms in the Banda Sea and in the Red Sea
Poding, L. H.; Jaegers, P.; Huhn, M.; Herlitze, S.; Senen, B.; Limmon, G. V.
10.1101/2023.09.22.559034 — zoology — Posted on 2024-02-19
1875 Impact of rice GENERAL REGULATORY FACTOR14h (GF14h) on low-temperature seed germination and its application to breeding
Sugimura, Y.; Oikawa, K.; Sugihara, Y.; Utsushi, H.; Kanzaki, E.; Ito, K.; Ogasawara, Y.; Fujioka, T.; Takagi, H.; Shimizu, M.; Shimono, H.; Terauchi, R.; Abe, A.
10.1101/2024.02.16.580620 — plant biology — Posted on 2024-02-19
1876 FLOWERING LOCUS C integrates carbon and nitrogen signaling for the proper timing of flowering in Arabidopsis
Gramma, V.; Olas, J. J.; Zacharaki, V.; Ponnu, J.; Luzarowska, U.; Musialak-Lange, M.; Wahl, V.
10.1101/2024.02.15.580522 — plant biology — Posted on 2024-02-19
1882 Transpiration efficiency variations in the pearl millet reference collection PMiGAP
Gregoire, L.; Kholova, J.; Srivastava, R.; Hash, C. T.; Vigouroux, Y.; Vadez, V.
10.1101/2024.02.16.580642 — plant biology — Posted on 2024-02-19
1883 Transport properties of canonical PIN-FORMED proteins and the role of the loop domain in auxin transport
Janacek, D. P.; Kolb, M.; Schulz, L.; Mergner, J.; Kuster, B.; Glanc, M.; Friml, J.; ten Tusscher, K.; Schwechheimer, C.; Hammes, U. Z.
10.1101/2024.02.15.580428 — plant biology — Posted on 2024-02-19
1884 Arabidopsis thaliana RHAMNOSE 1 condensate formation drives UDP-rhamnose synthesis
Field, S.; Dorone, Y.; Dwyer, W. P.; Cox, J. A.; Raba, D.; Froehlich, J.; Blea, M.; Carmo, O. M. S.; Wallace, I. S.; Hastings, R.; Boeynaems, S.; Rhee, S. Y.
10.1101/2024.02.15.580454 — plant biology — Posted on 2024-02-19
1889 Delay of innate immune responses following influenza B virus infection affects the development of robust antibody response in ferrets
Rowe, T.; Fletcher, A.; Richardson, R. A.; Lange, M.; Sautto, G. A.; Kirchenbaum, G. A.; Hatta, Y.; Jasso, G.; Wentworth, D. E.; Ross, T. M.
10.1101/2024.02.19.580935 — microbiology — Posted on 2024-02-19
1890 Enteral immunization with live bacteria reprograms innate immune cells and protects neonatal foals from pneumonia
da Silveira, B. P.; Kahn, S. K.; Legere, R. M.; Bray, J. M.; Cole-Pfeiffer, H. M.; Golding, M. C.; Cohen, N. D.; Bordin, A. I.
10.1101/2024.02.17.579919 — immunology — Posted on 2024-02-19
1891 Tissue-resident regulatory T cells exert dualistic anti-tumour and pro-repair function in the exocrine pancreas
Stockis, J.; Yip, T.; Raghunathan, S.; Garcia, C.; Lee, S.; Simpson, C.; Silvain, S.; Schuijs, M. J.; Araos, J.; Png, S.; Raddi, G.; Bricard, O.; So, T. Y.; Mack, S.; Papadopoulos, P.; Sawle, A.; Jodrell, D. I.; McKenzie, A. N. J.; Thaventhiran, J.; Clatworthy, M.; Biffi, G.; Saeb-Parsy, K.; Liston, A.; Halim, T. Y. F.
10.1101/2024.02.15.580302 — immunology — Posted on 2024-02-19
1894 Revealing 3D cancer tissue structures using holotomography and virtual hematoxylin and eosin staining via deep learning
park, J.; Shin, S.-J.; Kim, M.; kim, g.; cho, H.; ryu, d.; ahn, d.; heo, j. e.; min, h.-s.; Lee, K. S.; Park, Y.; Hwang, T. H.
10.1101/2023.12.04.569853 — cancer biology — Posted on 2024-02-19
1902 Multiomic single-cell sequencing defines tissue-specific responses in Stevens-Johnson Syndrome and Toxic epidermal necrolysis.
Gibson, A.; Ram, R.; Gangula, R.; Li, Y.; Mukherjee, E.; Palubinsky, A. M.; Campbell, C. N.; Thorne, M.; Konvinse, K. C.; Choshi, P.; Deshpande, P.; Pedretti, S.; O'Neil, R. T.; Wanjalla, C. N.; Kalams, S. A.; Gaudieri, S.; Lehloenya, R. J.; Bailin, S. S.; Chopra, A.; Trubiano, J. A.; Peter, J. G.; Mallal, S. A.; Phillips, E. J.
10.1101/2023.11.26.568771 — immunology — Posted on 2024-02-19
1906 A novel pyridoindole improves the recovery of residual hearing following cochlear implantation after a single preoperative application
Nieratschker, M.; Yildiz, E.; Gerlitz, M.; Bera, S.; Gadenstaetter, A. J.; Kramer, A.-M.; Kwiatkowska, M.; Mistrik, P.; Landegger, L. D.; Braun, S.; Schlingensiepen, R.; Honeder, C.; Arnoldner, C.; Rommelspacher, H.
10.1101/2024.02.14.580226 — neuroscience — Posted on 2024-02-19
1907 High-precision photoacoustic neural modulation uses a non-thermal mechanism
Chen, G.; Yu, F.; Shi, L.; Marar, C.; Du, Z.; Jia, D.; Cheng, J.-X.; Yang, C.
10.1101/2024.02.14.580331 — neuroscience — Posted on 2024-02-19
1911 Phylochemical mapping of natural products onto the plant tree of life using text mining and large language models.
Busta, L.; Hall, D.; Johnson, B.; Schaut, M.; Hanson, C. M.; Gupta, A.; Gondrum, M.; Wang, Y.; Maeda, H.
10.1101/2024.02.16.580694 — plant biology — Posted on 2024-02-19
1912 General Capillary Endothelial Cells Undergo Reprogramming into Arterial Endothelial Cells in Pulmonary Hypertension through HIF-2a/Notch4 Pathway
Liu, B.; Yi, D.; Xia, X.; Ramirez, K.; Zhao, H.; Cao, Y.; Dong, R.; Gao, A.; Ding, H.; Qiu, S.; Kalinichenko, V. V.; Fallon, M. B.; Dai, Z.
10.1101/2024.02.13.580227 — physiology — Posted on 2024-02-19
1914 Systematic characterization of protein structural features of alternative splicing isoforms using AlphaFold 2
Yang, Y.; Xie, Y.; Li, Z.; Diala, C.; Ali, M.; Li, R.; Xu, Y.; Wu, A.; Kim, P.; Hosseini, S.-R.; Bi, E.; Zhao, H.; Zheng, W. J.
10.1101/2024.01.30.578053 — bioinformatics — Posted on 2024-02-19
1917 Slc35a2 mosaic knockout impacts cortical development, dendritic arborisation, and neuronal firing in the developing brain
Spyrou, J.; Aung, K. P.; Vanyai, H.; Leventer, R. J.; Maljevic, S.; Lockhart, P. J.; Howell, K. B.; Reid, C. A.
10.1101/2024.02.18.580216 — neuroscience — Posted on 2024-02-18
1918 Mice lacking Astn2 have ASD-like behaviors and altered cerebellar circuit properties
Hanzel, M.; Fernando, K.; Maloney, S. E.; Gong, S.; Mätlik, K.; Zhao, J.; Pasolli, H. A.; Heissel, S.; Dougherty, J. D.; Hull, C.; Hatten, M. E.
10.1101/2024.02.18.580354 — neuroscience — Posted on 2024-02-18
1921 Transgenesis enables mapping of segmental ganglia in the leech Helobdella austinensis
Kuo, D.-H.; Szczupak, L.; Weisblat, D.; Portiansky, E.; Winchell, C.; Lee, J.-R.; Tsai, F.-Y.
10.1101/2024.02.14.580271 — zoology — Posted on 2024-02-18
1925 Adaptive diversification through structural variation in barley
Jayakodi, M.; Lu, Q.; Pidon, H.; Rabanus-Wallace, M. T.; Bayer, M.; Lux, T.; Guo, Y.; Jaegle, B.; Badea, A.; Bekele, W.; Brar, G.; Braune, K.; Bunk, B.; Chalmers, K.; Chapman, B.; Jorgensen, M. E.; Feng, J.-W.; Feser, M.; Fiebig, A.; Gundlach, H.; Guo, W.; Haberer, G.; Hansson, M.; Himmelbach, A.; Hoffie, I.; Hoffie, R.; Hu, H.; Isobe, S.; Koenig, P.; Kale, S.; Kamal, N.; Keeble-Gagnere, G.; Keller, B.; Knauft, M.; Koppolu, R.; Krattinger, S.; Kumlehn, J.; Langridge, P.; Li, C.; Marone, M.; Maurer, A.; Mayer, K.; Melzer, M.; Muehlbauer, G.; Murozuka, E.; Padmarasu, S.; Perovic, D.; Pillen, K.;
10.1101/2024.02.14.580266 — plant biology — Posted on 2024-02-18
1929 Molecular response to multiple trace-element contamination of the European sardine
Beauvieux, A.; Fromentin, J.-M.; Saraux, C.; Romero, D.; Couffin, N.; Brown, A.; Metral, L.; Bertile, F.; Schull, Q.
10.1101/2024.02.16.580673 — physiology — Posted on 2024-02-18
1930 Quantifying forms and functions of intestinal bile acid pools in mice
Sudo, K.; Delmas-Eliason, A.; Soucy, S.; Barrack, K. E.; Liu, J.; Balasubramanian, A.; Shu, C. J.; James, M.; Hegner, C. L.; Dionne, H. D.; Rodriguez-Palacios, A.; Krause, H.; O'Toole, G. A.; Karpen, S. J.; Dawson, P. A.; Schultz, D.; Sundrud, M. S.
10.1101/2024.02.16.580658 — physiology — Posted on 2024-02-18
1933 Limited parallelism in genetic adaptation to brackish water bodies in European sprat and Atlantic herring
Pettersson, M. E.; Quintela, M.; Besnier, F.; Deng, Q.; Berg, F.; Kvamme, C.; Bekkevold, D.; Mosbech, M.-B.; Bunikis, I.; Lille-Langoey, R.; Leonori, I.; Wallberg, A.; Glover, K. A.; Andersson, L.
10.1101/2024.02.16.580647 — genomics — Posted on 2024-02-18
1935 Functional brain imaging predicts population-level visits to urban spaces
Kaur, A.; Rodrigues, A. L.; Hoogstraten, S.; Blanco-Mora, D. A.; Miranda, B.; Morgado, P.; Meshi, D.
10.1101/2024.02.16.580650 — neuroscience — Posted on 2024-02-18
1936 Fluorescence Shadow Imaging of Hypsibius exemplaris Reveals Morphological Differences Between Sucrose- and CaCl2-Induced Osmobiotes
Flinn, B. B.; O'Dell, H. M.; Joseph, K. M.; Smythers, A. L.; Neff, D. P.; Hicks, L. M.; Norton, M. L.; Kolling, D. R.
10.1101/2024.02.14.580268 — physiology — Posted on 2024-02-18
1938 High-frequency amplitude-modulated sinusoidal stimulation induces desynchronized yet controllable neural firing
Barra, B.; Kumar, R.; Gopinath, C.; Mirzakhalili, E.; Lempka, S. F.; Gaunt, R. A.; Fisher, L. E.
10.1101/2024.02.14.580219 — bioengineering — Posted on 2024-02-18
1939 Molecular basis of inhibition of the amino acid transporter B0AT1 (SLC6A19)
Xu, J.; Hu, Z.; Dai, L.; Yadav, A.; Jiang, Y.; Broer, A.; Gardiner, M.; McLeod, M.; Yan, R.; Broer, S.
10.1101/2024.02.18.580905 — biochemistry — Posted on 2024-02-18
1940 Structural and biochemical analysis of a B12 super-binder
Martinez-Felices, J. M.; Whittaker, J. J.; Slotboom, D.; Guskov, A.
10.1101/2024.02.16.580637 — biochemistry — Posted on 2024-02-18
1942 The Cryptic Bacterial Microproteome
Fesenko, I.; Sahakyan, H.; Shabalina, S. A.; Koonin, E. V.
10.1101/2024.02.17.580829 — genomics — Posted on 2024-02-18
1943 Selection for later flowering time in an orchid through frost damage and pollinator activity
Wartmann, B.; Ruth, B.; Brigitte, G.-K.; Klaus, H.; Merz, E.; Luder, J.; Peter, B.; Reutlinger, M.; Richter, T.; Senn, H.; Ulrich, T.; Waldeck, B.; Wartmann, C.; Wuest, R.; Wuest, W.; Rusman, Q.; Schiestl, F. P.
10.1101/2024.02.14.580274 — evolutionary biology — Posted on 2024-02-18
1946 Workflow enhancement of TurboID-mediated proximity labeling for SPY signaling network mapping
Grismer, T. S.; Karundasa, S. S.; Shrestha, R.; Byun, D.; Ni, W.; Reyes, A. V.; xu, s.
10.1101/2024.02.17.580820 — molecular biology — Posted on 2024-02-18
1947 Transmission-blocking activity of artesunate, chloroquine and methylene blue on Plasmodium vivax gametocytes.
Chaumeau, V.; Wasisakun, P.; Watson, J. A.; Oo, T.; Aryalamloed, S.; Sue, M. P.; Htoo, G. N.; Tha, N. M.; Archusuksan, L.; Sawasdichai, S.; Gornsawun, G.; Mehra, S.; White, N. J.; Nosten, F.
10.1101/2024.02.18.580875 — microbiology — Posted on 2024-02-18
1948 The first discovery of SFTSV in the Centre of Metropolitan Beijing, China
Zheng, A.; Yuan, F.; Zhu, L.; Tian, D.; Xia, M.; Zheng, M.; Zhang, Q.; Zhang, T.; Zhang, X.
10.1101/2024.02.18.580844 — microbiology — Posted on 2024-02-18
1950 Dual Targeting of STING and PI3Kγ Eliminates Regulatory B Cells to Overcome STING Resistance for Pancreatic Cancer Immunotherapy
LI, C.; Mao, S.; Zhao, H.; He, M.; Wang, M.; Liu, Z.; Wen, H.; Yu, Z.; Wen, B.; Djibo, M.; Tao, J.; Bu, Y.; Gao, W.; Sun, D.
10.1101/2024.02.14.580378 — pharmacology and toxicology — Posted on 2024-02-18
1952 Aerobic exercise promotes PDAC vascular normalization through S1PR1 signaling in tumor endothelial cells
Ballaro, R.; Pareek, S.; Lee, J.; Patel, H.; Tirumala, P.; Liu, G.; Hayek, K.; Savage, H.; Guerrouahen, B.; Ngo-Huang, A.; Parker, N.; Katz, M. H.; Petzel, M.; McAllister, F.; Wright, R.; Tan, L.; Lorenzi, P. L.; Schadler, K.
10.1101/2024.02.14.580332 — cancer biology — Posted on 2024-02-18
1953 High-resolution single particle imaging at 100-200 keV with the Gatan Alpine direct electron detector.
Chan, L. M.; Courteau, B. J.; Maker, A.; Wu, M.; Basanta, B.; Mehmood, H.; Bulkley, D.; Joyce, D.; Lee, B. C.; Mick, S.; Gulati, S.; Lander, G. C.; Verba, K. A.
10.1101/2024.02.14.580363 — biophysics — Posted on 2024-02-18
1956 Long Read Sequencing reveals transgene concatemerization and backbone integration following AAV-driven electroporation of CRISPR RNP complexes in mouse zygotes
Luqman, M. W.; Jenjaroenpun, P.; Spathos, J.; Shingte, N.; Cummins, M.; Nimsamer, P.; Ittner, L. M.; Wongsurawat, T.; Delerue, F.
10.1101/2024.02.18.580906 — bioengineering — Posted on 2024-02-18
1957 Back-pocket optimization of 2-aminopyrimidine-based macrocycles leads to potent dual EPHA2/GAK kinase inhibitors with antiviral activity
Gerninghaus, J.; Zhubi, R.; Kraemer, A.; Karim, M.; Tran, D. H. N.; Joerger, A. C.; Schreiber, C.; Berger, L. M.; Berger, B. T.; Ehret, T. A. L.; Elson, L.; Lenz, C.; Saxena, K.; Mueller, S.; Einav, S.; Knapp, S.; Hanke, T.
10.1101/2024.02.18.580805 — biochemistry — Posted on 2024-02-18
1959 DEAD-box ATPase Dbp2 mediates mRNA release after 3'-end formation
Aydin, E.; Boehme, J.; Keil, B.; Schreiner, S.; Zunar, B.; Glatter, T.; Kilchert, C.
10.1101/2024.02.17.580811 — molecular biology — Posted on 2024-02-18
1960 Fertilization by short-term stored sperm alters DNA methylation patterns in common carp (Cyprinus carpio) embryos at single-base resolution
Cheng, Y.; Zhang, S.; Nayak, R.; Vechtova, P.; Schumacher, F.; Linhartova, P.; Gazo, I.; Linhartova, Z.; Waghmare, S. G.; Kleuser, B.; Dey, A.; Rodinova, V.; Rodina, M.; Sterba, J.; Alavi, S. M. H.; Labbe, C.; Linhart, O.
10.1101/2024.02.18.580899 — molecular biology — Posted on 2024-02-18
1961 Fecal Virome Transplantation (FVT) from healthy humans remodels the gut bacteriome and virome and reduces metabolic syndrome in mice
Cervantes-Echeverria, M. J.; Jimenez-Rico, M. A.; Manzo, R.; Hernandez-Reyna, A.; Cornejo-Granados, F.; Sanchez-Lopez, F.; Salazar-Leon, J.; Pedraza-Alva, G.; Perez-Martinez, L.; Ochoa-Leyva, A.
10.1101/2024.02.17.580809 — microbiology — Posted on 2024-02-18
1964 Micro-Scale Control of Oligodendrocyte Morphology and Myelination by the Intellectual Disability-Linked Protein Acyltransferase ZDHHC9
Jeong, H.-K.; Gonzalez-Fernandez, E.; Crawley, I.; Hwang, J.; Martin, D. D. O.; Bamji, S. X.; KIM, J.-I.; Kang, S.-H.; Thomas, G.
10.1101/2023.09.19.558291 — neuroscience — Posted on 2024-02-18
1966 After wounding, a G-protein coupled receptor promotes the restoration of tension in epithelial cells
Han, I.; Hua, J.; White, J. S.; O'Connor, J. T.; Nassar, L. S.; Tro, K. J.; Page-McCaw, A.; Hutson, M. S.
10.1101/2023.05.31.543122 — biophysics — Posted on 2024-02-18
1968 A biodegradable microgrooved and tissue mechanocompatible citrate-based scaffold improves bladder tissue regeneration
Goedegebuure, M.; Bury, M.; Wang, X.; San Felice, P.; Cammarata, F.; Wang, L.; Sharma, T.; Rajinikanth, N.; Karra, V.; Siddha, V.; Sharma, A.; Ameer, G.
10.1101/2024.02.15.580554 — bioengineering — Posted on 2024-02-18
1969 Discovery and characterization of chromosomal inversions in the arboviral vector mosquito Aedes aegypti
Liang, J.; Rose, N. H.; Brusentsov, I. I.; Lukyanchikova, V.; Karagodin, D. A.; Feng, Y.; Yurchenko, A. A.; Sylla, M.; Lutomiah, J.; Badolo, A.; Aribodor, O. B.; Ayala, D.; Acosta, C. G.; Alto, B. W.; Ahmad, N. W.; Tu, Z.; Gloria-Soria, A.; Black, W. C.; Powell, J.; Sharakhov, I. V.; McBride, C. S.; Sharakhova, M. V.
10.1101/2024.02.16.580682 — evolutionary biology — Posted on 2024-02-18
1970 Mechanisms of Epigenomic and Functional Convergence Between Glucocorticoid and IL4-Driven Macrophage Programming
Deochand, D. K.; Dacic, M.; Bale, M. J.; Daman, A. W.; Josefowicz, S. Z.; Oliver, D.; Chinenov, Y.; Rogatsky, I.
10.1101/2024.02.16.580560 — immunology — Posted on 2024-02-18
1971 MRI economics: Balancing sample size and scan duration in brain wide association studies
Ooi, L. Q. R.; Orban, C.; Nichols, T.; Zhang, S.; Tan, T. W. K.; Kong, R.; Marek, S.; Dosenbach, N. U. F.; Laumann, T. O.; Gordon, E. M.; Zhou, J. H.; Bzdok, D.; Eickhoff, S. B.; Holmes, A. J.; Yeo, B. T. T.
10.1101/2024.02.16.580448 — neuroscience — Posted on 2024-02-18
1972 AlphaFind: Discover structure similarity across the entire known proteome
Prochazka, D.; Slaninakova, T.; Olha, J.; Rosinec, A.; Gresova, K.; Janosova, M.; Cillik, J.; Porubska, J.; Svobodova, R.; Dohnal, V.; Antol, M.
10.1101/2024.02.15.580465 — bioinformatics — Posted on 2024-02-18
1973 InSilicoSeq 2.0: Simulating realistic amplicon-based sequence reads
Lelieveld, S. H.; Maas, T.; Duk, T. C. X.; Gourle, H.; van den Ham, H.-J.
10.1101/2024.02.16.580469 — bioinformatics — Posted on 2024-02-18
1976 Genome sequences of three Konjac mosaic virus (KoMV) variants
Breit, T. M.; de Leeuw, W. C.; van Olst, M. F.; Ensink, W. A.; van Leeuwen, S. M.; Jonker, M. J.; Dekker, R. J.
10.1101/2024.02.16.579633 — genomics — Posted on 2024-02-18
1979 Inflammatory pain resolution by mouse serum-derived small extracellular vesicles
Lin, Z.; Luo, X.; Wickman, J. R.; Reddy, D.; Pande, R.; Tian, Y.; Triana, V.; Lee, J.; Furdui, C. M.; Pink, D.; Sacan, A.; Ajit, S. K.
10.1101/2024.02.16.578759 — neuroscience — Posted on 2024-02-18
1980 Tracking single cell evolution via clock-like chromatin accessibility
Xiao, Y.; Jin, W.; Ju, L.; Fu, J.; Wang, G.; Yu, M.; Chen, F.; Qian, K.; Wang, X.; Zhang, Y.
10.1101/2022.05.12.491736 — bioinformatics — Posted on 2024-02-18
1981 SVarp: pangenome-based structural variant discovery
Soylev, A.; Ebler, J.; Pani, S.; Rausch, T.; Korbel, J.; Marschall, T.
10.1101/2024.02.18.580171 — bioinformatics — Posted on 2024-02-18
1985 Regression and Alignment for Functional Data and Network Topology
Tu, D.; Wrobel, J.; Satterthwaite, T. D.; Goldsmith, J.; Gur, R. C.; Gur, R. E.; Gertheiss, J.; Bassett, D. S.; Shinohara, R. T.
10.1101/2023.07.13.548836 — neuroscience — Posted on 2024-02-18
1989 Filamin A mediates embryonical palatal fusion by linking mechanotransduction with β-Catenin/Smad2
Wang, Z.; Hayano, S.; Weng, Y.; Mu, X.; Ono, M.; Pina, J. O.; D'Souza, R. N.; Yamashiro, T.; Oohashi, T.; Kamioka, H.
10.1101/2024.02.16.580664 — developmental biology — Posted on 2024-02-18
1990 Structural insights into IMP2 dimerization and RNA binding
Zorc, S.; Munoz-Tello, P.; O'Leary, T.; Yu, X.; Nag, M.; Hansel-Harris, A.; Forli, S.; Griffin, P. R.; Kojetin, D. J.; Roy, R. N.; Janiszewska, M.
10.1101/2024.02.16.580656 — molecular biology — Posted on 2024-02-18
1992 Identification of novel Bromodomain inhibitors of Trypanosoma cruzi Bromodomain Factor 2 (TcBDF2) using a fluorescence polarization-base high-throughput assay
Serra, E. C.; Tavernelli, L.; Alonso, V. L.; Pena, I.; Rodriguez Araya, E.; Manarin, R.; Cantizani, J.; Martin, J.; Salamanca, J.; Bamborough, P.; Calderon, F.; Gabarro, R.
10.1101/2024.02.16.580721 — microbiology — Posted on 2024-02-18
1994 TANK binding kinase 1 promotes BACH1 degradation through both phosphorylation-dependent and -independent mechanisms without relying on heme and FBXO22
Liu, L.; Matsumoto, M.; Matsui-Watanabe, M.; Nakagawa, T.; Nagasawa, Y.; Pang, J.; Callens, B. K. K.; Muto, A.; Ochiai, K.; Takekawa, H.; Alam, M.; Nishizawa, H.; Shirouzu, M.; Shima, H.; Nakayama, K.; Igarashi, K.
10.1101/2024.02.15.580587 — biochemistry — Posted on 2024-02-18
1996 PTBP2 promotes cell survival and autophagy in Chronic Myeloid Leukemia by stabilizing BNIP3
Barik, B.; Lama, S.; IS, S.; Chanda, S.; Biswas, S.; Biswas, G.; Mohapatra, S.; chakraborty, S.
10.1101/2024.01.26.577177 — cancer biology — Posted on 2024-02-18
1998 Streamlined regulation of chloroplast development in the liverwort Marchantia polymorpha
Yelina, N. E.; Frangedakis, E.; Wang, Z.; Schreier, T. B.; Rever, J.; Tomaselli, M.; Forestier, E.; Billakurthi, K.; Ren, S.; Bai, Y.; Stewart-Wood, J.; Haseloff, J.; Zhong, S.; Hibberd, J. M.
10.1101/2023.01.23.525199 — plant biology — Posted on 2024-02-18
1999 Androgen deprivation triggers a cytokine signaling switch to induce immune suppression and prostate cancer recurrence
Sha, K.; Zhang, R.; Maolake, A.; Singh, S.; Chatta, G.; Eng, K. H.; Nastiuk, K. L.; Krolewski, J. J.
10.1101/2023.12.01.569685 — cancer biology — Posted on 2024-02-18
2002 Volumetric trans-scale imaging of massive quantity of heterogeneous cell populations in centimeter-wide tissue and embryo
Ichimura, T.; Kakizuka, T.; Sato, Y.; Itano, K.; Seiriki, K.; Hashimoto, H.; Itoga, H.; Onami, S.; Nagai, T.
10.1101/2023.08.21.553997 — developmental biology — Posted on 2024-02-18
2004 Stem-loop induced ribosome queuing in the uORF2/ATF4 overlap fine-tunes stress-induced human ATF4 translational control
Smirnova, A. M.; Hronova, V.; Mohammad, M. P.; Herrmannova, A.; Gunisova, S.; Petrackova, D.; Halada, P.; Coufal, S.; Swirski, M.; Rendelman, J.; Jendruchova, K.; Hatzoglou, M.; Beznoskova, P.; Vogel, C.; Valasek, L. S.
10.1101/2023.07.12.548609 — molecular biology — Posted on 2024-02-18
2007 Nanopore-based consensus sequencing enables accurate multimodal tumor cell-free DNA profiling
Chen, L.-T.; Jager, M.; Rebergen, D.; Brink, G. J.; van den Ende, T.; Vanderlinden, W.; Kolbeck, P.; Pages-Gallego, M.; van der Pol, Y.; Besselink, N.; Moldovan, N.; Hami, N.; Kloosterman, W.; van Laarhoven, H.; Mouliere, F.; Zweemer, R.; Lipfert, J.; Derks, S.; Marcozzi, A.; de Ridder, J.
10.1101/2024.02.16.580684 — genomics — Posted on 2024-02-17
2010 Tobacco Images Choice and Its Association with Craving and Dependence in Cigarette Smokers
Solinas, M.; Chauvet, C.; Lafay-Chebassier, C.; Vanderkam, P.; Barillot, L.; Moeller, S. J.; Goldstein, R. Z.; Noel, X.; Jaafari, N.; Chatard, A.
10.1101/2023.08.30.555462 — neuroscience — Posted on 2024-02-17
2012 Depression Attenuates Caudate and Dorsolateral Prefrontal Cortex Alpha and Beta Power Response to Reward
Qian, H.; Johnson, G. W.; Hughes, N. C.; Paulo, D. L.; Zhao, Z.; Subramanian, D.; Dhima, K.; Bick, S. K.
10.1101/2024.02.05.578848 — neuroscience — Posted on 2024-02-17
2015 A comprehensive evaluation of taxonomic classifiers in marine vertebrate eDNA studies
Bayer, P. E.; Bennett, A.; Nester, G.; Corrigan, S.; Raes, E. J.; McInnes, A. S.; Cooper, M.; Ayad, M. E.; McVey, P.; Kardailsky, A.; Pearce, J.; Fraser, M. W.; Goncalves, P.; Burnell, S.; Rauschert, S.
10.1101/2024.02.15.580601 — ecology — Posted on 2024-02-17
2016 Genes required for the formation of virulence-provoking bacterial sphingolipids
Olea-Ozuna, R. J.; Poggio, S.; Bergström, E.; Osorio, A.; ELUFISAN, T. O.; Padilla-Gomez, J.; Martinez-Aguilar, L.; Lopez-Lara, I. M.; Thomas-Oates, J.; Geiger, O.
10.1101/2024.02.16.580706 — microbiology — Posted on 2024-02-17
2017 Asgard archaea defense systems and their roles in the origin of immunity in eukaryotes
Leao, P.; Little, M. E.; Appler, K. E.; Sahaya, D.; Aguilar-Pine, E.; Currie, K.; Finkelstein, I. J.; De Anda, V.; Baker, B. J.
10.1101/2023.09.13.557551 — microbiology — Posted on 2024-02-17
2021 Architecture of the spinach plastid-encoded RNA polymerase
Wang, T.; Wang, G.; Fang, Y.; Zhang, Y.; Peng, W.; Zhou, Y.; Zhang, A.; Yu, L.-J.; Lu, C.
10.1101/2024.02.16.580782 — biochemistry — Posted on 2024-02-17
2022 A new chromosome-level genome assembly and annotation of Cryptosporidium meleagridis
Penumarthi, L. R.; de Paula Baptista, R. C.; Beaudry, M. S.; Glenn, T.; Kissinger, J. C.
10.1101/2024.02.16.580748 — genomics — Posted on 2024-02-17
2023 CYP1A1/1A2 enzymes mediate glucose homeostasis and insulin secretion in mice in a sex-specific manner
Ching, M. E. A.; Hoyeck, M. P.; Basu, L.; Merhi, R.; van Zyl, E.; Crawley, A. M.; Bruin, J. E.
10.1101/2024.02.16.580670 — molecular biology — Posted on 2024-02-17
2025 Gammaherpesvirus infection alters transfer RNA splicing and triggers tRNA cleavage
Manning, A. C.; Bashir, M. M.; Jimenez, A. C.; Upton, H. E.; Collins, K.; Lowe, T. M.; Tucker, J. M.
10.1101/2024.02.16.580780 — microbiology — Posted on 2024-02-17
2028 Elucidating effects of single and multiple resistance mechanisms on bacterial response to meropenem by quantitative and systems pharmacology modeling and population genomics
Fuhs, D. T.; Cortes-Lara, S.; Tait, J. R.; Rogers, K. E.; Lopez-Causape, C.; Lee, W. L.; Shackleford, D. M.; Nation, R. L.; Oliver, A.; Landersdorfer, C. B.
10.1101/2024.02.17.579784 — microbiology — Posted on 2024-02-17
2031 A General Mechanism for the General Stress Response in Bacteria
Baral, R.; Ho, K.; Ramasamy, P. K.; Hopkins, J. B.; Watkins, M. B.; LaRussa, S.; Caban=Penix, S.; Calderone, L. A.; Bradshaw, N.
10.1101/2024.02.16.580724 — microbiology — Posted on 2024-02-17
2033 Engineering BCMA CAR T cells for myeloma-targeted cargo delivery
Kimman, T.; Cuenca, M.; Slomp, A.; Tieland, R. G.; Rockx-Brouwer, D.; Heijhuurs, S.; Meringa, A. D.; Boschloo, W.; Bosma, D. M.; Kroos, S.; lo Presti, V.; Nierkens, S.; Bovenschen, N.; Kuball, J.; Minnema, M. C.; Sebestyen, Z.; Peperzak, V.
10.1101/2024.02.14.580301 — immunology — Posted on 2024-02-17
2035 Degron-based bioPROTACs for controlling signaling in CAR T cells
Kim, M. S.; Bhargava, H. K.; Shavey, G. E.; Lim, W. A.; El-Samad, H.; Ng, A. H.
10.1101/2024.02.16.580396 — synthetic biology — Posted on 2024-02-17
2039 Deciphering the History of ERK Activity from Fixed-Cell Immunofluorescence Measurements
Ram, A.; Pargett, M.; Choi, Y.; Murphy, D.; Cabel, M.; Kosaisawe, N.; Quon, G.; Albeck, J.
10.1101/2024.02.16.580760 — molecular biology — Posted on 2024-02-17
2041 Glycolytic reprogramming shapes the epigenetic landscape of activated CD4+ T Cells in Juvenile Idiopathic Arthritis
Mocholi, E.; Chalkiadakis, T.; Gulersonmez, C.; Stigter, E.; Vastert, B.; van Loosdregt, J.; Prekovic, S.; Coffer, P.
10.1101/2024.02.14.580242 — immunology — Posted on 2024-02-17
2044 Human iPSC-derived Committed Cardiac Progenitors Generate Cardiac Tissue Grafts in a Swine Ischemic Cardiomyopathy Model without Triggering Ventricular Arrhythmias
Raval, A. N.; Schmuck, E. G.; Roy, S.; Saito, Y.; Zhou, T.; Conklin, J.; Hacker, T. A.; Koonce, C.; Boyer, M.; Stack, K.; Hebron, E.; Nagle, S. K.; Hsieh, P. C. H.; Kamp, T. J.
10.1101/2024.02.14.580375 — pathology — Posted on 2024-02-17
2045 Resistance to Naive and Formative Pluripotency Conversion in RSeT Human Embryonic Stem Cells
Chen, K. G.; Johnson, K. J.; Park, K.; Maric, D.; Yang, F.; Liu, W. F.; Fann, Y. C.; Mallon, B. S.; Robey, P. G.
10.1101/2024.02.16.580778 — cell biology — Posted on 2024-02-17
2047 Collapse of late endosomal pH elicits a rapid Rab7 response via V-ATPase and RILP.
Mulligan, R. J.; Magaj, M. M.; Digilio, L.; Redemann, S.; Yap, C. C.; Winckler, B.
10.1101/2023.10.24.563658 — cell biology — Posted on 2024-02-17
2049 Molecular glues of the regulatory ChREBP/14-3-3 complex protect beta cells from glucolipotoxicity.
Katz, L. S.; Visser, E. J.; Plitzko, K. F.; Pennings, M.; Cossar, P. J.; Tse, I. L.; Kaiser, M.; Brunsveld, L.; Scott, D. K.; Ottmann, C.
10.1101/2024.02.16.580675 — cell biology — Posted on 2024-02-17
2051 Trajectory analysis of hepatic stellate cell differentiation reveals metabolic regulation of cell commitment and fibrosis
Martinez Garcia de la Torre, R. A.; Vallverdu, J.; Xu, Z.; Arino, S.; Aguilar-Bravo, B.; Ruiz Blazquez, P.; Fernandez Fernandez, M.; Navarro-Gascon, A.; Blasco-Roset, A.; Sanchez--Fernandez-de-Landa, P.; Pera Garcia, J.; Romero-Moya, D.; Ayuso Garcia, P.; Martinez Sanchez, C.; Zanatto, L.; Sererols, L.; Cantallops Vila, P.; Antoine, B.; Azkargorta, M.; Lozano, J. J.; Martinez-Chantar, M. L.; Giorgetti, A.; Elortza, F.; Planavila, A.; Varela, M.; Woodhoo, A.; Zorzano, A.; Graupera, I.; Moles, A.; Coll, M.; Affo, S.; Sancho-Bru, P.
10.1101/2024.02.15.577777 — cell biology — Posted on 2024-02-17
2054 SLAM/SAP signaling regulates discrete γδ T cell developmental checkpoints and shapes the innate-like γδ TCR repertoire
Mistri, S. K.; Hilton, B. M.; Horrigan, K. J.; Andretta, E. S.; Savard, R.; Dienz, O.; Hampel, K. J.; Gerrard, D. L.; Rose, J. T.; Sidiropoulos, N.; Majumdar, D.; Boyson, J. E.
10.1101/2024.01.10.575073 — immunology — Posted on 2024-02-17
2057 The highly repetitive genome of Myxobolus sp., a myxozoan parasite of fathead minnows
Muthye, V. R.; Leon Coria, A.; Liu, H.; Finney, C. A. M.; Goater, C. P.; Wasmuth, J. D.
10.1101/2024.02.09.579586 — zoology — Posted on 2024-02-17
2059 Disrupting CD38-driven T cell dysfunction restores sensitivity to cancer immunotherapy
Revach, O.-Y.; Cicerchia, A. M.; Shorer, O.; Petrova, B.; Anderson, S.; Park, J.; Chen, L.; Mehta, A.; Wright, S. J.; McNamee, N.; Tal-Mason, A.; Cattaneo, G.; Tiwari, P.; Xie, H.; Sweere, J. M.; Cheng, L.-C.; Sigal, N.; Enrico, E.; Miljkovic, M.; Evans, S. A.; Nguyen, N.; Whidden, M. E.; Srinivasan, R.; Spitzer, M. H.; Sun, Y.; Sharova, T.; Lawless, A.; Michaud, W. A.; Rasmussen, M. Q.; Fang, J.; Palin, C.; Chen, F.; Wang, X.; Ferrone, C. R.; Lawrence, D. P.; Sullivan, R. J.; Liu, D.; Sachdeva, U. M.; Sen, D. R.; Flaherty, K. T.; Manguso, R. T.; Bod, L.; Kellis, M.; Boland, G. M.; Yizhak, K.;
10.1101/2024.02.12.579184 — cancer biology — Posted on 2024-02-17
2062 Partial RNA Design
Runge, F.; Franke, J. K. H.; Fertmann, D.; Backofen, R.; Hutter, F.
10.1101/2023.12.29.573656 — bioinformatics — Posted on 2024-02-17
2066 A Quantum Computing Pipeline for Real World Drug Discovery: From Algorithm to Quantum Hardware
Li, W.; Yin, Z.; Li, X.; Ma, D.; Yi, S.; Zhang, Z.; Zou, C.; Bu, K.; Dai, M.; Yue, J.; Chen, Y.; Zhang, X.; Zhang, S.
10.1101/2024.01.08.574600 — bioinformatics — Posted on 2024-02-17
2067 Supercontinuum intrinsic fluorescence imaging heralds free view of living systems
Wang, G.; Li, L.; Liao, X.; Wang, S.; Mitchell, J.; Rabel, C.; Luo, S.; Shi, J.; Sorrells, J. E.; Iyer, R. R.; Aksamitiene, E.; Renteria, C. A.; Chaney, E. J.; Milner, D. J.; Wheeler, M. B.; Gillette, M. U.; Schwing, A.; Chen, J.; Tu, H.
10.1101/2024.01.26.577383 — bioengineering — Posted on 2024-02-17
2072 Striatal Dopamine Can Enhance Learning, Both Fast and Slow, and Also Make it Cheaper
Westbrook, A.; van den Bosch, R.; Hofmans, L.; Papadopetraki, D.; Maatta, J. I.; Collins, A. G. E.; Frank, M. J.; Cools, R.
10.1101/2024.02.14.580392 — animal behavior and cognition — Posted on 2024-02-17
2073 Sex-specific fear acquisition following early life stress is linked to amygdala glutamate metabolism
Bordes, J.; Bajaj, T.; Miranda, L.; van Doeselaar, L.; Brix, L. M.; Narayan, S.; Yang, H.; Mitra, S.; Kovarova, V.; Springer, M.; Kleigrewe, K.; Mueller-Myhsok, B.; Gassen, N. C.; Schmidt, M. V.
10.1101/2024.02.15.580479 — animal behavior and cognition — Posted on 2024-02-17
2075 Linear Interaction Between Replication and Transcription Shapes DNA Break Dynamics at Recurrent DNA Break Clusters
Corazzi, L.; Ionasz, V.; Andrejev, S.; Wang, L.-C.; Vouzas, A.; Giaisi, M.; Di Muzio, G.; Ding, B.; Marx, A.; Henkenjohann, J.; Allers, M. M.; Gilbert, D. M.; Wei, P.-C.
10.1101/2023.08.22.554340 — genomics — Posted on 2024-02-17
2076 Evaluation and optimization of sequence-based gene regulatory deep learning models
Rafi, A. M.; Nogina, D.; Penzar, D.; Lee, D.; Lee, D.; Kim, N.; Kim, S.; Kim, D.; Shin, Y.; Kwak, I.-Y.; Meshcheryakov, G.; Lando, A.; Zinkevich, A.; Kim, B.-C.; Lee, J.; Kang, T.; Vaishnav, E. D.; Yadollahpour, P.; DREAM Challenge Consortium, R. P.; Kim, S.; Albrecht, J.; Regev, A.; Gong, W.; Kulakovskiy, I. V.; Meyer, P.; de Boer, C.
10.1101/2023.04.26.538471 — genomics — Posted on 2024-02-17
2077 Multifocal Ectopic Purkinje Premature Contractions due to neutralization of an SCN5A negative charge: structural insights into the gating pore hypothesis
Roden, D. M.; Glazer, A. M.; Yang, T.; Page, D.; Fouda, M.; Wada, Y.; Lancaster, M. C.; O'Neill, M. J.; Muhammad, A.; Gao, X.; Ackerman, M. J.; Sanatani, S.; Ruben, P.; Li, B.
10.1101/2024.02.13.580021 — genetics — Posted on 2024-02-17
2078 50,000 years of Evolutionary History of India: Insights from ~2,700 Whole Genome Sequences
Kerdoncuff, E.; Skov, L.; Patterson, N.; Zhao, W.; Lueng, Y. Y.; Schellenberg, G. D.; Smith, J. A.; Dey, S.; Ganna, A.; Dey, A.; Kardia, S. L. R.; Lee, J.; Moorjani, P.
10.1101/2024.02.15.580575 — evolutionary biology — Posted on 2024-02-17
2080 Ivermectin resistance in dung beetles exposed for multiple generations
Tokman, D. G.; Torres, A. A.; Baena-Diaz, F.; Bustos, C.; Martinez M, I.
10.1101/2023.05.08.539900 — ecology — Posted on 2024-02-17
2082 A CPF-like phosphatase module links transcription termination to chromatin silencing
Mateo Bonmati, E.; Montez, M.; Maple, R.; Fiedler, M.; Fang, X.; Saalbach, G.; Passmore, L. A.; Dean, C. A.
10.1101/2023.07.06.547976 — molecular biology — Posted on 2024-02-17
2085 Infant and Adult Human Intestinal Enteroids are Morphologically and Functionally Distinct
Adeniyi-Ipadeola, G. O.; Hankins, J. D.; Kambal, A.; Zeng, X.-L.; Patil, K.; Poplaski, V.; Bomidi, C.; Nguyen-Phuc, H.; Grimm, S. L.; Coarfa, C.; Stossi, F.; Crawford, S. E.; Blutt, S. E.; Speer, A. L.; Estes, M. K.; Ramani, S.
10.1101/2023.05.19.541350 — microbiology — Posted on 2024-02-17
2087 Multi-omic profiling of pathogen-stimulated primary immune cells
Salz, R.; Vorsteveld, E. E.; van der Made, C. I.; Kersten, S.; Stemerdink, M.; Hsieh, T.; Mhlanga, M.; Netea, M.; Volders, P.-J.; Hoischen, A.; 't Hoen, P. A. C.
10.1101/2023.09.13.557514 — immunology — Posted on 2024-02-17
2088 Anterior thalamus functional connectivity with cortical regions underpinning prospective memory: a 7-Tesla fMRI seed-based study
Flanagan, L.; Mansur, B. d. M.; Reichert, C.; Richter, A.; Golbabaei, S.; Kizilirmak, J. M.; Sweeney-Reed, C. M.
10.1101/2024.02.14.580346 — neuroscience — Posted on 2024-02-17
2091 Investigating altered limbic reward system in Huntington's Disease: Implications for apathy
Bikou, V.; de Vicente, I.; De Paepe, A. E.; Garcia-Gorro, C.; Rodriguez-Dechicha, N.; Vaquer, I.; Calopa, M.; de Diego-Balaguer, R.; Camara, E.
10.1101/2024.02.13.580195 — neuroscience — Posted on 2024-02-17
2094 Scaling Properties for Artificial Neural Network Models of a Small Nervous System
Simeon, Q.; Venancio, L. R.; SKUHERSKY, M.; Yang, G.; Boyden, E. S.; Nayebi, A.
10.1101/2024.02.13.580186 — neuroscience — Posted on 2024-02-17
2095 YY1 mutations disrupt corticogenesis through a cell-type specific rewiring of cell-autonomous and non-cell-autonomous transcriptional programs
Pereira, M. F.; Finazzi, V.; Rizzuti, L.; Aprile, D.; Aiello, V.; Mollica, L.; Riva, M.; Soriani, C.; Dossena, F.; Shyti, R.; Castaldi, D.; Tenderini, E.; Carminho-Rodrigues, M. T.; Bally, J. F.; de Vries, B. B. A.; Gabriele, M.; Vitriolo, A.; Testa, G.
10.1101/2024.02.16.580337 — neuroscience — Posted on 2024-02-17
2098 Cortical beta oscillations map to shared brain networks modulated by dopamine
Chikermane, M.; Weedmeester, L.; Rajamani, N.; Köhler, R. M.; Merk, T.; Vanhoecke, J.; Horn, A.; Neumann, W.-J.
10.1101/2024.02.16.580657 — neuroscience — Posted on 2024-02-17
2099 Engineering the cyanobacterial ATP-driven BCT1 bicarbonate transporter for functional targeting to C3 plant chloroplasts
Rottet, S.; Rourke, L. M.; Pabuayon, I. C. M.; Phua, S. Y.; Yee, S.; Weerasooriya, H. N.; Wang, X.; Mehra, H. S.; Nguyen, N. D.; Long, B. M.; Moroney, J. V.; Price, G. D.
10.1101/2024.02.14.580295 — plant biology — Posted on 2024-02-17
2100 Functional Characterisation of the ATOH1 Molecular Subtype Indicates a Pro-Metastatic Role in Small Cell Lung Cancer
Catozzi, A.; Peiris-Pages, M.; Humphrey, S.; Revill, M.; Morgan, D.; Roebuck, J.; Chen, Y.; Davies-Williams, B.; Lallo, A.; Galvin, M.; Pearce, S. P.; Kerr, A.; Priest, L.; Foy, V.; Carter, M.; Caeser, R.; Chan, J.; Rudin, C. M.; Blackhall, F.; Frese, K. K.; Dive, C.; Simpson, K. L.
10.1101/2024.02.16.580247 — cancer biology — Posted on 2024-02-17
2101 Ultrastructure expansion microscopy (U-ExM) of mouse and human kidneys for analysis of subcellular structures
Langner, E.; Puapatanakul, P.; Pudlowski, R.; Alsabbagh, D. Y.; Miner, J.; Horani, A.; Dutcher, S. K.; Brody, S. L.; Wang, J.; Suleiman, H. Y.; Mahjoub, M. R.
10.1101/2024.02.16.580708 — cell biology — Posted on 2024-02-17
2103 Structural characterization and dynamics of AdhE ultrastructures from Clostridium thermocellum: A containment strategy for toxic intermediates?
Ziegler, S. J.; Knott, B.; Gruber, J. N.; Hengge, N. N.; Xu, Q.; Olson, D. G.; Romero, E. E.; Joubert, L.-M.; Bomble, Y. J.
10.1101/2024.02.16.580662 — biophysics — Posted on 2024-02-16
2104 PIMENTA: PIpeline for MEtabarcoding through Nanopore Technology used for Authentication
van der Vorst, V.; Thijssen, M.; Fronen, B. J.; de Groot, A.; Maathuis, M. A. M.; Nijhuis, E.; Polling, M.; Stassen, J.; Voorhuijzen-Harink, M. M.; Jak, R.
10.1101/2024.02.14.580249 — bioinformatics — Posted on 2024-02-16
2105 Tissue Tension and Strain as Indicators of Suction-mediated Cutaneous DNA Transfection: A Parametric Study
Jhumur, N. C.; Lallow, E. O.; Nachtigal, C.; Yeo, D.; Kwon, I.; Park, Y. K.; Roberts, C. C.; Zahn, J. D.; Shreiber, D. I.; Shan, J. W.; Singer, J. P.; Maslow, J. N.; Lin, H.
10.1101/2024.02.15.580412 — bioengineering — Posted on 2024-02-16
2110 Sub-optimal activity of gut microbiome functional pathways increases the odds of Irritable Bowel Syndrome in a large adult human population
Patridge, E.; Gorakshakar, A.; Molusky, M. M.; Ogundijo, O.; Julian, C.; Hu, L.; Vuyisich, M.; Wohlman, R.; Banavar, G.
10.1101/2024.02.15.580548 — microbiology — Posted on 2024-02-16
2111 High density genomic surveillance and risk profiling of clinical Listeria monocytogenes subtypes in Germany, 2018-2021
Halbedel, S.; Wamp, S.; Lachmann, R.; Holzer, A.; Pietzka, A.; Ruppitsch, W.; Wilking, H.; Flieger, A.
10.1101/2024.02.16.580625 — microbiology — Posted on 2024-02-16
2115 Engineering the cyanobacterial ATP-driven BCT1 bicarbonate transporter for functional targeting to C3 plant chloroplasts
Rottet, S.; Rourke, L. M.; Pabuayon, I. C. M.; Phua, S. Y.; Yee, S.; Weerasooriya, H. N.; Wang, X.; Mehra, H. S.; Nguyen, N. D.; Long, B. M.; Moroney, J. V.; Price, G. D.
10.1101/2024.02.14.580295 — plant biology — Posted on 2024-02-16
2116 DOPAMINE D4 RECEPTOR DOWN-REGULATES RENAL SODIUM CHLORIDE COTRANSPORTER VIA UBIQUITINATION-ASSOCIATED LYSOSOME DEGRADATION
Zhang, M.; Liu, M.; Ren, Z.; Wang, W.; Upadhyay, K.; Asico, L. A.; Armando, I.; Jia, Y.; Wang, P.; Xue, Y.; Wang, X.
10.1101/2024.02.14.580405 — physiology — Posted on 2024-02-16
2119 Systemically targeting monocytic MDSCs using dendrimers and their cell-level biodistribution kinetics
Littrell, C. A.; Takacs, G. P.; Siva Sankara, C.; Sherman, A.; Rubach, K. A.; Garcia, J. S.; Bell, C.; Harrison, J. K.; Zhang, F.
10.1101/2024.02.14.580395 — bioengineering — Posted on 2024-02-16
2122 The activation chain of the broad-spectrum antiviral bemnifosbuvir at atomic resolution
Chazot, A.; Zimberger, C.; Feracci, M.; Moussa, A.; Good, S.; Sommadossi, J.-P.; ALVAREZ, K.; Ferron, F.; Canard, B.
10.1101/2024.02.16.580631 — biochemistry — Posted on 2024-02-16
2123 Joint, multifaceted genomic analysis enables diagnosis of diverse, ultra-rare monogenic presentations
Kobren, S. N.; Moldovan, M. A.; Reimers, R.; Traviglia, D.; Li, X.; Barnum, D.; Veit, A.; Willett, J.; Berselli, M.; Ronchetti, W.; Sherwood, R.; Krier, J.; Kohane, I. S.; Undiagnosed Diseases Network, ; Sunyaev, S. R.
10.1101/2024.02.13.580158 — genetics — Posted on 2024-02-16
2125 Transinfection of Wolbachia wAlbB into Culex quinquefasciatus mosquitoes does not alter vector competence for Hawaiian avian malaria (Plasmodium relictum GRW4)
Kilpatrick, A. M.; Seidl, C. M.; Ipsaro, I. J.; Garrison, C. E.; Fabbri, G.; Howell, P. I.; McGowan, A. G.; White, B. J.; Mitchell, S. N.
10.1101/2024.02.16.580617 — ecology — Posted on 2024-02-16
2126 H-NS is a bacterial transposon capture protein
Cooper, C.; Legood, S.; Wheat, R. L.; Forrest, D.; Sharma, P.; Haycocks, J. R.; Grainger, D. C.
10.1101/2024.02.16.580519 — microbiology — Posted on 2024-02-16
2127 Molecular switching of a DNA-sliding clamp to a repressor mediates long-range gene silencing
McLean, T. C.; Balaguer-Perez, F.; Chandanani, J.; Thomas, C. M.; Aicart-Ramos, C.; Burick, S.; Olinares, P. D. B.; Gobbato, G.; Mundy, J. E. A.; Chait, B. T.; Lawson, D. M.; Darst, S. A.; Campbell, E. A.; Moreno-Herrero, F.; Le, T. B. K.
10.1101/2024.02.16.579611 — microbiology — Posted on 2024-02-16
2128 Microbial community assembly during aging of food waste-derived hydrochar: key bacterial guilds mediate nutrient dynamics
Ruan, Y.; Wang, Z.; Tan, S.; Xu, H.; Wang, L.; Ren, L.; Liu, Z.; Guo, S.; Shen, Q.; Xu, G.; Ling, N.
10.1101/2024.02.16.580608 — microbiology — Posted on 2024-02-16
2129 The polysaccharide capsule of Acinetobacter baumannii affects bacterial adhesion and natural transformation
Whiteway, C.; de Pillecyn, V.; Maure, A.; Breine, A.; Valcek, A.; Van Buylaere, J.; Van der Henst, C.
10.1101/2024.02.15.580542 — microbiology — Posted on 2024-02-16
2131 Revealing nanoscale structure and interfaces of protein and polymer condensates via cryo-electron microscopy
RIZVI, A.; Favetta, B.; Jaber, N.; Lee, Y.-k.; Jiang, J.; Idris, N.; Schuster, B. S.; Dai, W.; Patterson, J. P.
10.1101/2024.02.15.577400 — biophysics — Posted on 2024-02-16
2132 Circadian rhythms of macrophages are altered by the acidic pH of the tumor microenvironment
Knudsen-Clark, A. M.; Mwangi, D.; Cazarin, J.; Hablitz, L. M.; Kim, M.; Altman, B. J.
10.1101/2024.02.14.580339 — immunology — Posted on 2024-02-16
2137 Phasing Diploid Genome Assembly Graphs with Single-Cell Strand Sequencing
Henglin, M.; Ghareghani, M.; Harvey, W.; Porubsky, D.; Koren, S.; Eichler, E. E.; Ebert, P.; Marschall, T.
10.1101/2024.02.15.580432 — bioinformatics — Posted on 2024-02-16
2138 Population genomics of the rice landrace Acuce reveals exceptional dynamics of immune receptors
De Mita, S.; Duan, S.; Li, X.; Pelissier, R.; Mathieu, L.; Li, J.; Ma, L.; Li, Z.; Liao, J.; He, X.; Zhu, Y.; Li, C.; Dong, Y.; Morel, J.-b.; Huang, H.
10.1101/2024.02.15.579491 — genomics — Posted on 2024-02-16
2141 Epigenomic profiling of active regulatory elements by enrichment of unmodified CpG dinucleotides
Tosti, L.; Mould, C.; Gatehouse, I.; Camargo, A.; Smith, A.; Ubych, K.; Laird, P. W.; Kennefick, J.; Neely, R. K.
10.1101/2024.02.16.575381 — genomics — Posted on 2024-02-16
2142 Sex differences in immune function and disease risk are not easily explained by an evolutionary mismatch
Arner, A. M.; Muhoya, B.; Rozado, M. S.; Gurven, M. R.; Kahumbu, J.; Kamau, J.; Kinyua, P.; Lotukoi, F.; Martins, D. J.; Miano, C.; Montague, M. J.; Njeru, S.; Peng, J.; Straub, P.; Watowich, M. M.; Davis, L. K.; Snyder-Mackler, N.; Ayroles, J. F.; Lea, A. J.
10.1101/2024.02.13.580011 — evolutionary biology — Posted on 2024-02-16
2143 Phylogenomic and genomic analysis reveals unique and shared genetic signatures of Mycobacterium kansasii complex species
Machado, E.; Vasconcellos, S.; Gomes, L.; Catanho, M.; Ramos, J.; de Carvalho, L.; Goldenberg, T.; Dalcolmo, M.; Redner, P.; Caldas, P.; Campos, C.; Lourenco, M. C.; Lasunskaia, E.; Mussi, V.; Spinasse, L.; Vinhas, S.; Rigouts, L.; Cogneau, S.; de Rijk, P.; Utpatel, C.; Kaustova, J.; van der Laan, T.; de Neeling, H.; Rastogi, N.; Levina, K.; Kutt, M.; Mokrousov, I.; Zhuravlev, V.; Makhado, N.; Zolnir-Dovc, M.; Jankovic, V.; de Waard, J.; Sisco, M.; van Soolingen, D.; Niemann, S.; de Jong, B. C.; Meehan, C. J.; Suffys, P.
10.1101/2024.02.14.579889 — evolutionary biology — Posted on 2024-02-16
2145 Fusion, fission, and scrambling of the bilaterian genome in Bryozoa
Lewin, T. D.; Liao, I. J.-Y.; Chen, M.-E.; Bishop, J. D. D.; Holland, P. W. H.; Luo, Y.-J.
10.1101/2024.02.15.580425 — evolutionary biology — Posted on 2024-02-16
2146 Robust Neutralization of SARS-CoV-2 Variants Including JN.1 and BA.2.87.1 by Trivalent XBB Vaccine-Induced Antibodies
Wang, X.; Jiang, S.; Ma, W.; Li, C.; Liu, C.; Xie, F.; Zhu, J.; Zhan, Y.; Jiang, S.; Li, M.; Zhang, Y.; Wang, P.
10.1101/2024.02.16.580615 — microbiology — Posted on 2024-02-16
2147 Exposure to cooler temperatures during pupal development increases Aedes aegypti vector competence and the R0 for Zika virus
Pohlenz, T. D.; Vela, J.; Reyna, M.; Fredregill, C.; Hur, B.; Erraguntla, M.; Lawley, M.; Debboun, M.; Adelman, Z. N.; Ndeffo-Mbah, M. L.; Myles, K. M.
10.1101/2024.02.16.580619 — microbiology — Posted on 2024-02-16
2148 Targeting a specific motor control process reveals an age-related compensation that adapts movement to gravity environment
MATHIEU, R.; Chambellant, F.; Thomas, E.; Papaxanthis, C.; Hilt, P.; Manckoundia, P.; Mourey, F.; Gaveau, J.
10.1101/2024.02.16.576683 — neuroscience — Posted on 2024-02-16
2149 YY1 mutations disrupt corticogenesis and cytoarchitecture through a cell-type specific rewiring of cell-autonomous and non-cell-autonomous transcriptional programs
Pereira, M. F.; Finazzi, V.; Rizzuti, L.; Aprile, D.; Aiello, V.; Mollica, L.; Riva, M.; Soriani, C.; Dossena, F.; Shyti, R.; Castaldi, D.; Tenderini, E.; Carminho-Rodrigues, M. T.; Bally, J. F.; de Vries, B. B. A.; Gabriele, M.; Vitriolo, A.; Testa, G.
10.1101/2024.02.16.580337 — neuroscience — Posted on 2024-02-16
2159 Biophysics of microRNA-34a targeting and its influence on down-regulation
Sweetapple, L.; Kosek, D.; Banijamali, E.; Becker, W.; Mueller, J.; Karadiakos, C.; Baronti, L.; Guzzetti, I.; Schritt, D.; Chen, A.; Andersson, E. R.; Petzold, K.
10.1101/2024.02.14.580117 — biophysics — Posted on 2024-02-16
2161 Neuroestrogens facilitate male-typical behaviors by potentiating androgen receptor signaling in medaka
Nishiike, Y.; Maki, S.; Miyazoe, D.; Nakasone, K.; Kamei, Y.; Todo, T.; Ishikawa-Fujiwara, T.; Ohno, K.; Usami, T.; Nagahama, Y.; Okubo, K.
10.1101/2024.02.13.580203 — physiology — Posted on 2024-02-16
2162 Analog epigenetic cell memory by graded DNA methylation
Palacios, S.; Bruno, S.; Weiss, R.; Salibi, E.; Kane, A.; Ilia, K.; Del Vecchio, D.
10.1101/2024.02.13.580200 — bioengineering — Posted on 2024-02-16
2163 UHRF1 ubiquitin ligase activity supports the maintenance of low-density CpG methylation
Tiedemann, R.; Hrit, J.; Du, Q.; Wiseman, A. K.; Eden, H. E.; Dickson, B. M.; Kong, X.; Chomiak, A.; Vaughan, R. M.; Hebert, J. M.; David, Y.; Zhou, W. M.; Baylin, S.; Jones, P. A.; Clark, S.; Rothbart, S. B.
10.1101/2024.02.13.580169 — genomics — Posted on 2024-02-16
2164 Distinct sets of molecular characteristics define tumor-rejecting neoantigens
Adams, A. C.; Macy, A. M.; Borden, E. S.; Herrmann, L. M.; Brambley, C. A.; Ma, T.; Li, X.; Hughes, A.; Roe, D. J.; Mangold, A. R.; Buetow, K. H.; Wilson, M. A.; Baker, B. M.; Hastings, K. T.
10.1101/2024.02.13.579546 — immunology — Posted on 2024-02-16
2168 Adeno-Associated Viral Tools to Trace Neural Development and Connectivity Across Amphibians
Jaeger, E. C. B.; Vijatovic, D.; Deryckere, A.; Zorin, N.; Nguyen, A. L.; Ivanian, G.; Woych, J.; Arnold, R. C.; Ortega Gurrola, A.; Shvartsman, A.; Barbieri, F.; Toma, F. A.; Gorbsky, G. J.; Horb, M. E.; Cline, H. T.; Shay, T. F.; Kelley, D. B.; Yamaguchi, A.; Shein-Idelson, M.; Tosches, M. A.; Sweeney, L. B.
10.1101/2024.02.15.580289 — neuroscience — Posted on 2024-02-16
2169 Vitamin D is Glucoprotective in Aging Males but Not Females
Ginnard, O. Z. B.; Morales, M.; Youn, J. Y.; Xu, Y.; Sisley, S. R.
10.1101/2024.02.13.580162 — physiology — Posted on 2024-02-16
2170 Multifocal Ectopic Purkinje Premature Contractions due to neutralization of an SCN5A negative charge: structural insights into the gating pore hypothesis
Roden, D. M.; Glazer, A. M.; Yang, T.; Page, D.; Fouda, M.; Wada, Y.; Lancaster, M. C.; O'Neill, M. J.; Muhammad, A.; Gao, X.; Ackerman, M. J.; Sanatani, S.; Ruben, P.; Li, B.
10.1101/2024.02.13.580021 — genetics — Posted on 2024-02-16
2171 A Spatial Prioritization of Conifer Management to Defend and Grow Sagebrush Cores
Reinhardt, J. R.; Maestas, J.; Naugle, D. E.; Bedrosian, G.; Doherty, K.; Kumar, A.
10.1101/2024.02.13.579706 — ecology — Posted on 2024-02-16
2173 Multifunctional biomimetic porphyrin-lipid nanoparticles - novel nanoscale theranostics for atherosclerotic cardiovascular disease
Nankivell, V.; Sandeman, L.; Stretton, L. G.; Vidanapathirana, A.; Rajora, M. A.; Chen, J.; Tieu, W.; Psaltis, P. J.; Tan, J. T. M.; Chen, Y.-C.; Peter, K.; Zheng, G.; Bursill, C. A.
10.1101/2024.02.13.580218 — cell biology — Posted on 2024-02-16
2175 Milteforan, a promising veterinary commercial product against feline sporotrichosis
Carnero, L. G.; dos Reis, T. F.; Diehl, C.; de Castro, P. A.; Pontes, L.; Pinzan, C. F.; Goldman, G. H.
10.1101/2024.02.14.580352 — microbiology — Posted on 2024-02-16
2180 Cancer-Specific Alterations in Nuclear Matrix Proteins Determined by Multi-omics Analyses of Ductal Carcinoma in Situ
Almutairy, A.; Alhamed, A.; Grant, S.; Sarachine Falso, M. J.; Day, B.; Simmons, C. R.; Latimer, J. J.
10.1101/2024.02.13.580215 — cancer biology — Posted on 2024-02-16
2181 Identification of retinal tau oligomers, citrullinated tau, and other tau isoforms in early and advanced AD and relations to disease status
Shi, H.; Mirzaei, N.; Koronyo, Y.; Davis, M. R.; Robinson, E.; Braun, G. M.; Jallow, O.; Rentsendorj, A.; Ramanujan, V. K.; Fert-Bober, J.; Kramerov, A. A.; Ljubimov, A. V.; Schneider, L. S.; Tourtellotte, W. G.; Hawes, D.; Schneider, J. A.; Black, K. L.; Kayed, R.; Selenica, M.-L. B.; Lee, D. C.; Fuchs, D.-T.; Koronyo-Hamaoui, M.
10.1101/2024.02.13.579999 — pathology — Posted on 2024-02-16
2182 Structural enrichment attenuates colitis-associated colon cancer
Sykes, D. J.; Solanki, S.; Chukkapalli, S.; Williams, K.; Newman, E. A.; Resnicow, K.; Shah, Y. M. J.
10.1101/2024.02.13.580099 — cancer biology — Posted on 2024-02-16
2183 The Interaction of NF-κB Transcription Factor with Centromeric Chromatin
Filliaux, S. B.; Bertelsen, C.; Baughman, H. E. R.; Komives, E. A. A.; Lyubchenko, Y. L.
10.1101/2024.02.13.580208 — biophysics — Posted on 2024-02-16
2185 Diversity in the Utilization of Different Molecular Classes of Dissolved Organic Matter by Heterotrophic Marine Bacteria
Givati, S. H.; Forchielli, E. J.; Aharonovich, D.; Barak, N.; Weissberg, O.; Belkin, N.; Rahav, E.; Segre, D.; Sher, D.
10.1101/2024.02.13.580157 — microbiology — Posted on 2024-02-16
2186 Neutrophils in People Living With HIV-1 on antiretroviral treatment conserve their cytokine and chemokine secretion capacity and display enhanced expression of Fc receptors
Marsile-Medun, S.; Souchard, M.; Abba Moussa, D.; Lorin, V.; Mouquet, H.; Reynaud, E.; Dibsy, R.; TUAILLON, E.; MURIAUX, D.; Pugniere, M.; Ngo, G.; Naranjo-Gomez, M.; Pelegrin, M.
10.1101/2024.02.13.580065 — immunology — Posted on 2024-02-16
2188 Soft Tissue Mechanics in Hip Distraction after Total Knee Arthroplasty: A Finite Element Analysis
Soehnlen, S. M.; Sadeqi, S.; Kumaran, Y.; Tripathi, S.; Jones, R. K.; Sohn, D. H.; Goel, V. K.
10.1101/2024.02.13.580129 — bioengineering — Posted on 2024-02-16
2193 CoRAL accurately resolves extrachromosomal DNA genomestructures with long-read sequencing
Zhu, K.; Jones, M. G.; Luebeck, J.; Bu, X.; Yi, H.; Hung, K. L.; Wong, I. T.-L.; Zhang, S.; Mischel, P. S.; Chang, H. Y.; Bafna, V.
10.1101/2024.02.15.580594 — cancer biology — Posted on 2024-02-16
2194 Matrix-rigidity cooperates with biochemical cues in M2 macrophage activation through increased nuclear deformation and chromatin accessibility
Shin, S.-J.; Bayarkhangai, B.; Tsogtbaataar, K.; Yuxuan, M.; Kim, S.-H.; Kim, Y.-J.; Kim, D.; Kim, D.-H.; Lee, J.-H.; Hyun, J.; Kim, H.-W.
10.1101/2024.02.13.579995 — bioengineering — Posted on 2024-02-16
2199 A Vascular Dissection and Rupture Linked Metabolite Acts Via BLT2 Receptor
Wang, Y.; Li, Y.; Yu, J.; Chen, W.; Tan, X.; Xu, X.; Lin, R.; Wang, X.; Jiang, W.; Du, J.
10.1101/2024.02.15.580482 — cell biology — Posted on 2024-02-16
2201 Lysosomal uptake of mtDNA mitigates heteroplasmy
Kakanj, P.; Bonse, M.; Gokmen, A.; Gaedke, F.; Molla, B.; Vogelsang, E.; Schauss, A.; Wodarz, A.; Pla-Martin, D.
10.1101/2024.02.16.580263 — cell biology — Posted on 2024-02-16
2202 The co-chaperone DNAJA2 buffers proteasomal degradation of cytosolic proteins with missense mutations
Baker, H. A.; Bernardini, J. P.; Csizmok, V.; Madero, A.; Kamat, S.; Eng, H.; Lacoste, J.; Yeung, F.; Comyn, S.; Calabrese, G.; Taipale, M.; Raught, B.; Mayor, T.
10.1101/2024.02.15.580437 — cell biology — Posted on 2024-02-16
2204 The Role of Sex in the Effects of Smoking and Nicotine in Cardiovascular Function, Atherosclerosis, and Inflammation
Salazar, G.; Centner, A. M.; Cullen, A. E.; Khalili, L.; Ukhanov, V.; Hill, S.; Deitado, R.; Hwang, H. S.; Azeez, T.; La Favor, J. D.; Laitano, O.; Parvatiyar, M. S.
10.1101/2024.02.13.580217 — cell biology — Posted on 2024-02-16
2206 CRM1 regulates androgen receptor stability and impacts DNA repair pathways in prostate cancer, independent of the androgen receptor.
Kumar, R.; Mendonca, J.; Shetty, A.; Yang, Y.; Owoyemi, O.; Wilson, L. C.; Boyapati, K.; Topiwala, D.; Thomas, N.; Nguyen, H.; Luo, J.; Paller, C. J.; Denmeade, S. R.; Carducci, M. A.; Kachhap, S. K.
10.1101/2024.02.13.579966 — cancer biology — Posted on 2024-02-16
2207 Doubling the resolution of fluorescence-lifetime single-molecule localization microscopy with image scanning microscopy
Radmacher, N.; Nevskyi, O.; Gallea, J. I.; Thiele, J. C.; Gregor, I.; Rizzoli, S. O.; Enderlein, J.
10.1101/2023.08.23.554438 — biophysics — Posted on 2024-02-16
2215 Overcoming the nutritional immunity by engineering iron scavenging bacteria for cancer therapy
Huang, S.-W.; Lim, S.-K.; Yu, Y.-A.; Pan, Y.-C.; Lien, W.-J.; Mou, C.-Y.; Hu, C.-M. J.; Mou, K. Y.
10.1101/2023.07.25.550605 — bioengineering — Posted on 2024-02-16
2219 A ratiometric ER calcium sensor for quantitative comparisons across cell types and subcellular regions
Farrell, R. J.; Bredvik, K. G.; Hoppa, M. B.; Hennegan, S. T.; Brown, T. A.; Ryan, T. A.
10.1101/2024.02.15.580492 — cell biology — Posted on 2024-02-16
2220 Oxytocin signaling regulates maternally-directed behavior during early life
Zelmanoff, D.; Kaufman, M.; Dine, J.; Wietek, J.; Litvin, A.; Abraham, S.; Cohen, S.; Yizhar, O.
10.1101/2024.02.15.580483 — neuroscience — Posted on 2024-02-15
2222 Multi-species community platform for comparative neuroscience in teleost fish
Vohra, S.; Herrera, K.; Tavhelidse-Suck, T.; Wittbrodt, J.; Knoblich, S.; Seleit, A.; Aulehla, A.; Boulanger-Weill, J.; Chambule, S.; Aspiras, A.; Santoriello, C.; Fishman, M. C.; Hege, H.-C.; Baum, D.; Engert, F.; Isoe, Y.
10.1101/2024.02.14.580400 — neuroscience — Posted on 2024-02-16
2226 Rubisco supplies pyruvate for the 2-C-methyl-D-erythritol-4-phosphate pathway
Evans, S. E.; Xu, Y.; Bergman, M. E.; Ford, S.; Liu, Y.; Sharkey, T.; Phillips, M. A.
10.1101/2024.01.28.577108 — plant biology — Posted on 2024-02-16
2227 Distinct patterns of genetic variation at low-recombining genomic regions represent haplotype structure
Ishigohoka, J.; Bascon-Cardozo, K.; Bours, A.; Fuss, J.; Rhie, A.; Mountcastle, J.; Haase, B.; Chow, W.; Collins, J.; Howe, K.; Uliano-Silva, M.; Fedrigo, O.; Jarvis, E. D.; Perez-Tris, J.; Illera, J. C.; Liedvogel, M.
10.1101/2021.12.22.473882 — evolutionary biology — Posted on 2024-02-16
2228 Early mechanisms of aortic failure in a zebrafish model for thoracic aortic dissection and rupture
Vanhooydonck, M.; Verlee, M.; Silva, M. S.; Pottie, L.; Boel, A.; Van Impe, M.; De Saffel, H.; Caboor, L.; Tapaneeyaphan, P.; Bonnin, A.; Segers, P.; De Clercq, A.; Willaert, A.; Syx, D.; Sips, P.; Callewaert, B.
10.1101/2024.02.12.580022 — developmental biology — Posted on 2024-02-16
2229 Transient Impairment in Microglial Function Causes Sex-Specific Deficits in Synaptic and Hippocampal Function in Mice Exposed to Early Adversity
Ahmed, S.; Polis, B.; Jamwal, S.; Sanganahalli, B. G.; MacDowell Kaswan, Z.; Islam, R.; Kim, D.; Bowers, C.; Giuliano, L.; Biederer, T.; Hyder, F.; Kaffman, A.
10.1101/2024.02.14.580284 — neuroscience — Posted on 2024-02-15
2230 Shared and unique consequences of Joubert Syndrome gene dysfunction on the zebrafish central nervous system
Noble, A. R.; Masek, M.; Hofmann, C.; Cuoco, A.; Rusterholz, T. D. S.; Ozkoc, H.; Greter, N. R.; Vladimirov, N.; Kollmorgen, S.; Stoeckli, E.; Bachmann-Gagescu, R.
10.1101/2024.02.15.580456 — neuroscience — Posted on 2024-02-15
2232 Long-term adaptation of prefrontal circuits in a mouse model of NMDAR hypofunction
Ponserre, M. A.; Ionescu, T. M.; Franz, A. A.; Deiana, S.; Schuelert, N.; Lamla, T.; Williams, R. H.; Wotjak, C. T.; Hobson, S.; Dine, J. P. P.; Omrani, A.
10.1101/2024.02.15.580421 — neuroscience — Posted on 2024-02-15
2233 Single Transcript Level Atlas of Oxytocin and the Oxytocin Receptor in the Mouse Brain
Ryu, V.; Gumerova, A. A.; Pevnev, G.; Korkmaz, F.; Kannangara, H.; Cullen, L.; Witztum, R.; Sims, S. L.; Frolinger, T.; Moldavski, O.; Barak, O.; Cao, J. J.; Lizneva, D.; Goosens, K. A.; Yuen, T.; Zaidi, M.
10.1101/2024.02.15.580498 — physiology — Posted on 2024-02-15
2234 CellsFromSpace: A fast, accurate and reference-free tool to deconvolve and annotate spatially distributed Omics data
Thuilliez, C.; Moquin-Beaudry, G.; Khneisser, p.; Marques Da Costa, M. E.; Karkar, S.; Boudhouche, H.; Drubay, D.; Audinot, B.; Geoerger, B.; Scoazec, J.-Y.; Gaspar, N.; Marchais, A.
10.1101/2023.08.30.555558 — bioinformatics — Posted on 2024-02-15
2236 Pleotropic effects of a recessive COL1A2 mutation occurring in a mouse model of severe osteogenesis imperfecta
Corcelli, M.; Sagar, R.; Petzendorfer, E.; Hasan, M. M.; de Vries, H. I.; van Dijk, F. S.; David, A. L.; Guillot, P. V.
10.1101/2024.02.15.580510 — genetics — Posted on 2024-02-15
2237 Brain-handedness associations depend on how and when handedness is measured
Tejavibulya, L.; Horien, C.; Fredricks, C.; Ficek-Tani, B.; Westwater, M. L.; Scheinost, D.
10.1101/2024.02.15.580563 — neuroscience — Posted on 2024-02-15
2240 A Fast Interferometric Beam Shaper for Multi-Emitter 3D MINFLUX
Geismann, M. K.; Gomez-Segalas, A.; Passera, A.; Shirzadian, M.; Balzarotti, F.
10.1101/2023.12.09.570565 — biophysics — Posted on 2024-02-15
2243 Convergent origin and accelerated evolution of vesicle-associated RhoGAP proteins in two unrelated parasitoid wasps
Colinet, D.; Cavigliasso, F.; Leobold, M.; Pichon, A.; Urbach, S.; Cazes, D.; Poullet, M.; Belghazi, M.; Volkoff, A.-N.; Drezen, J.-M.; Gatti, J.-L.; Poirie, M.
10.1101/2023.06.05.543686 — evolutionary biology — Posted on 2024-02-15
2244 Tree diversity increases forest temperature buffering
Schnabel, F.; Beugnon, R.; Yang, B.; Richter, R.; Eisenhauer, N.; Huang, Y.; Liu, X.; Wirth, C.; Cesarz, S.; Fichtner, A.; Perles-Garcia, M. D.; Hähn, G. J. A.; Härdtle, W.; Kunz, M.; Castro Izaguirre, N. C.; Niklaus, P. A.; von Oheimb, G.; Schmid, B.; Trogisch, S.; Wendisch, M.; Ma, K.; Bruelheide, H.
10.1101/2023.09.11.556807 — ecology — Posted on 2024-02-15
2246 Human ADA2 deficiency is characterized by the absence of an intracellular hypoglycosylated form of adenosine deaminase 2
Ehlers, L.; Hombrouck, A.; Wouters, M.; Pillay, B.; Delafontaine, S.; Bucciol, G.; Baggio, M.; Dzhus, M.; Ebstein, F.; Jacquemyn, M.; De Somer, L.; Schrijvers, R.; Vanderschueren, S.; Cassiman, D.; Kirchner, M.; Mertins, P.; Kallinich, T.; Daelemans, D.; Agostinis, P.; Moens, L.; Meyts, I.
10.1101/2023.10.25.564037 — immunology — Posted on 2024-02-15
2247 Counter-regulation of RNA stability by UPF1 and TDP43
Gomez, N.; Hsieh, C.; Li, X.; Dykstra, M.; Waksmacki, J.; Altheim, C.; Bechar, Y.; Klim, J.; Zaepful, B.; Rothstein, J.; Tank, E. M.; Barmada, S. J.
10.1101/2024.01.31.578310 — neuroscience — Posted on 2024-02-15
2250 PI-(3,5)P2-mediated oligomerization of the endosomal sodium/proton exchanger NHE9
Kokane, S.; Meier, P.; Gulati, A.; Matsuoka, R.; Pipatpolkai, T.; Albano, G.; Delemotte, L.; Fuster, D.; Drew, D.
10.1101/2023.09.10.557050 — biochemistry — Posted on 2024-02-15
2252 Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes
Xiang, G.; He, X.; Giardine, B. M.; Isaac, K. J.; Taylor, D. J.; McCoy, R. C.; Jansen, C.; Keller, C. A.; Wixom, A. Q.; Cockburn, A.; Miller, A.; Qi, Q.; He, Y.; Li, Y.; Lichtenberg, J.; Heuston, E. F.; Anderson, S. M.; Luan, J.; Vermunt, M. W.; Yue, F.; Sauria, M. E. G.; Schatz, M. C.; Taylor, J.; Gottgens, B.; Hughes, J. R.; Higgs, D. R.; Weiss, M. J.; Cheng, Y.; Blobel, G. A.; Bodine, D. M.; Zhang, Y.; Li, Q.; Mahony, S.; Hardison, R. C.
10.1101/2023.04.02.535219 — genomics — Posted on 2024-02-15
2255 Old, broad-leaved stands support both high biodiversity and carbon storage in German forests
Springer, K.; Manning, P.; Boesing, A. L.; Ammer, C.; Fiore-Donno, A. M.; Fischer, M.; Goldmann, K.; Le Provost, G.; Overmann, J.; Ruess, L.; Schoening, I.; Seibold, S.; Sikorski, J.; Neyret, M.
10.1101/2024.02.06.578731 — ecology — Posted on 2024-02-15
2257 Discovery of an endogenous DNA virus in the amphibian killing fungus and its association with pathogen genotype and virulence
Clemons, R.; Yacoub, M.; Faust, E.; Toledo, L. F.; Jenkinson, T. S.; Carvalho, T.; Simmons, D. R.; Kalinka, E.; Fritz-Laylin, L. K.; James, T. Y.; Stajich, J. E.
10.1101/2023.03.16.532857 — microbiology — Posted on 2024-02-15
2263 On-farm hatching and contact with adult hen post hatch induce sex-dependent effects on performance and welfare in broiler chickens
Guilloteau, L. A.; Bertin, A.; Crochet, S.; Bagnard, C.; Hondelatte, A.; Ravon, L.; Schouler, C.; Germain, K.; Collin, A.
10.1101/2023.05.17.541117 — physiology — Posted on 2024-02-15
2267 Comparing sparse inertial sensor setups for sagittal-plane walking and running reconstructions
Dorschky, E.; Nitschke, M.; Mayer, M.; Weygers, I.; Gassner, H.; Seel, T.; Eskofier, B.; Koelewijn, A.
10.1101/2023.05.25.542228 — bioengineering — Posted on 2024-02-15
2269 The online metacognitive control of decisions
Benon, J.; Lee, D. G.; Hopper, W.; Verdeil, M.; Pessiglione, M.; Vinckier, F.; Bouret, S.; Rouault, M.; Lebouc, R.; Pezzulo, G.; Schreiweis, C.; Burguiere, E.; Daunizeau, J.
10.1101/2023.01.02.522463 — animal behavior and cognition — Posted on 2024-02-15
2271 Bending Unwinds DNA
Chandrasekhar, S.; Swope, T. P.; Fadaei, F.; Hollis, D. R.; Bricker, R.; Houser, D.; Portman, J.; Schmidt, T. L.
10.1101/2024.02.14.579968 — biophysics — Posted on 2024-02-15
2274 Investigating T cell Recruitment in Atherosclerosis using a novel Human 3D Tissue-Culture Model reveals the role of CXCL12 in intraplaque neovessels
Parma, L.; Sachs, N.; Li, Z.; Merchant, K.; Sobczak, N.; Slutter, B.; Maegdefessel, L.; Weber, C.; Megens, R.; Duchene, J.
10.1101/2024.02.14.580316 — molecular biology — Posted on 2024-02-15
2278 Feed-forward stimulation of CAMK2 by the oncogenic pseudokinase PEAK1 generates a therapeutically "actionable" signalling axis in triple negative breast cancer
Yang, X.; Ma, X.; Croucher, D. R.; Nguyen, E. V.; Clark, K. C.; Hu, C.; Latham, S. L.; Zhao, T.; Bayly-Jones, C.; Nguyen, V. C. B.; Shin, S.; Nguyen, L. K.; Cotton, T. R.; Chueh, A. C.; Sian, T. C. L. K.; Stratton, M. M.; Ellisdon, A. M.; Daly, R. J.
10.1101/2024.02.14.580406 — cancer biology — Posted on 2024-02-15
2280 The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA.
Hengel, S. R.; Oppenheimer, K.; Smith, C.; Schaich, M.; Rein, H. L.; Martino, J.; Darrah, K.; Ezekwenna, O. C.; Burton, K. R.; Van Houten, B.; Spies, M.; Bernstein, K. A.
10.1101/2024.02.14.580393 — biochemistry — Posted on 2024-02-15
2281 The NAPstar family of NADP redox state sensors highlights glutathione as the primary mediator of anti-oxidative electron flux
Scherschel, M.; Niemeier, J.-O.; Jacobs, L.; Hoffmann, M.; Diederich, A.; Bell, C.; Hoehne, P.; Raetz, S.; Kroll, J.; Steinbeck, J.; Lichtenauer, S.; Multhoff, J.; Zimmermann, J.; Sadhanasatish, T.; Rothemann, R. A.; Grashoff, C.; Messens, J.; Ampofo, E.; Laschke, M. W.; Riemer, J.; Roma, L. P.; Schwarzlander, M.; Morgan, B.
10.1101/2024.02.14.580349 — biochemistry — Posted on 2024-02-15
2284 Discovery of Alkenyl Oxindole as a Novel PROTAC Moiety for Targeted Protein Degradation via CRL4DCAF11 Recruitment
Wang, Y.; Wei, T.; Zhao, M.; Huang, A.; Sun, F.; Chen, L.; Lin, R.; Xie, Y.; Zhang, M.; Xu, S.; Sun, Z.; Hong, L.; Wang, R.; Tian, R.; Li, G.
10.1101/2024.02.15.580430 — biochemistry — Posted on 2024-02-15
2285 T cell interaction partners of DHHC20
Haxhiraj, D.; Kuropka, B.; Brencher, E.; Rosenberger, D.; Brandt, H.; Speck, D.; Scheerer, P.; Bruegger, B.; Clementi, C.; Freund, C.
10.1101/2024.02.14.580290 — biochemistry — Posted on 2024-02-15
2286 Multiomics uncovers the epigenomic and transcriptomic response to viral and bacterial stimulation in turbot
Aramburu, O.; Pardo, B. G.; Rodriguez-Villamayor, P.; Blanco Hortas, A.; Lamas, J.; Dewari, P. S.; Perojil, D.; Boudinot, P.; Macqueen, D. J.; Bouza, C.; Martinez, P.
10.1101/2024.02.15.580452 — genomics — Posted on 2024-02-15
2287 A missense variant effect map for the human tumour suppressor protein CHK2
Gebbia, M.; Zimmerman, D. I.; Jiang, R.; Nguyen, M.; Weile, J.; Li, R.; Gavac, M.; Kishore, N.; Sun, S.; Boonen, R. A.; Dines, J. N.; Wahl, A.; Reuter, J.; Johnson, B.; Fowler, D.; van Attikum, H.; Roth, F. P.
10.1101/2024.02.13.579700 — genetics — Posted on 2024-02-15
2288 Predictable functional biogeography of marine microbial heterotrophs
Zakem, E. J.; McNichol, J.; Weissman, J. L.; Raut, Y.; Xu, L.; Halewood, E. R.; Carlson, C. A.; Dutkiewicz, S.; Fuhrman, J. A.; Levine, N. M.
10.1101/2024.02.14.580411 — ecology — Posted on 2024-02-15
2292 A fungal metabolic regulator underlies infectious synergism during Candida albicans-Staphylococcus aureus intra-abdominal co-infection
Paul, S.; Todd, O. A.; Eichelberger, K. R.; Tkaczyk, C.; Sellman, B. R.; Noverr, M. C.; Cassat, J. E.; Fidel, P. L.; Peters, B. M.
10.1101/2024.02.15.580531 — microbiology — Posted on 2024-02-15
2297 Optical Control of Cell-Surface and Endomembrane-Exclusive β-Adrenergic Receptor Signaling
Thotamune, W.; Ubeysinghe, S.; Shrestha, K. K.; Mostafa, M. E.; Young, M. C.; Karunarathne, A.
10.1101/2024.02.14.580335 — biochemistry — Posted on 2024-02-15
2301 Bioengineering secreted proteases converts divergent Rcr3 orthologs and paralogs into extracellular immune co-receptors
Kourelis, J.; Schuster, M.; Demir, F.; Mattinson, O.; Krauter, S.; Kahlon, P. S.; O'Grady, R.; Royston, S.; Bravo-Cazar, A. L.; Mooney, B. C.; Huesgen, P. F.; Kamoun, S.; van der Hoorn, R. A. L.
10.1101/2024.02.14.580413 — plant biology — Posted on 2024-02-15
2302 Decoding proteome functional information in model organisms using protein language models.
Barrios-Nunez, I.; Martinez-Redondo, G. I.; Medina-Burgos, P.; Cases, I.; Fernandez, R.; Rojas, A. M.
10.1101/2024.02.14.580341 — bioinformatics — Posted on 2024-02-15
2303 Transcription Factors with Broad Expression in the Zebrafish Spinal Cord
England, S. J.; Campbell, P.; Bates, R.; Grieb, G.; Fancher, W.; Lewis, K.
10.1101/2024.02.14.580357 — developmental biology — Posted on 2024-02-15
2304 Local variation in brain temperature explains gender-specificity of working memory performance
Rogala, J.; Dreszer, J.; Sinczuk, M.; Miciuk, Łukasz; Piatkowska-Janko, E.; Bogorodzki, P.; Wolak, T.; Wrobel, A.; Konarzewski, M.
10.1101/2024.02.14.580344 — neuroscience — Posted on 2024-02-15
2306 Thyroid Hormone Suppresses Medulloblastoma Progression Through Promoting Terminal Differentiation of Tumor Cells
Yang, Z.; Yang, Y.; Valdes-Rives, S. A.; Liu, Q.; Li, Y.; Tan, J.; Tan, Y.; Koch, C. A.; Rong, Y.; Houser, S. R.; Wei, S.; Cai, K.; Cheng, S.-y.; Curran, T.; Wechsler-Reya, R.
10.1101/2024.02.13.580111 — cancer biology — Posted on 2024-02-15
2307 Canine major histocompatibility complex class I (MHC-I) diversity landscape
Feng, Y.; Ho, K.-L.; Zhang, M.; Sundaresha, N. B.; Cavanagh, H. L.; Zhao, S.
10.1101/2024.02.14.580220 — bioinformatics — Posted on 2024-02-15
2313 Recurrent loss of crossover interference punctuates the recombination landscape across yeast species
Dutta, A.; Dutreux, F.; Garin, M.; Caradec, C.; Friedrich, A.; Brach, G.; Thiele, P.; llorente, b.; Schacherer, J.
10.1101/2024.02.13.580081 — genomics — Posted on 2024-02-15
2314 UBA1-CDK16: A Sex-Specific Chimeric RNA and Its Role in Immune Sexual Dimorphism
Shi, X.; Facemire, L.; Singh, S.; Kumar, S.; Cornelison, R.; Liang, C.; Qin, F.; Liu, A.; Lin, S.; Tang, Y.; Elfman, J.; Manley, T.; Bullock, T.; Haverstick, D.; Wu, P.; Li, H.
10.1101/2024.02.13.580120 — genomics — Posted on 2024-02-15
2316 Long-range chemical signalling in vivo is regulated by mechanical signals
Pillai, E. K.; Mukherjee, S.; Gampl, N.; McGinn, R. J.; Mooslehner, K. A.; Thompson, A. J.; Franze, K.
10.1101/2024.02.15.580459 — developmental biology — Posted on 2024-02-15
2319 A single-dose MCMV-based vaccine elicits long-lasting immune protection in mice against distinct SARS-CoV-2 variants
Metzdorf, K.; Jacobsen, H.; Kim, Y.; Teixeira Alves, L. G.; Kulkarni, U.; Eschke, K.; Chaudhry, M. Z.; Hoffmann, M.; Bertoglio, F.; Ruschig, M.; Hust, M.; Brdovcak, M. C.; Materljan, J.; Sustic, M.; Krmpotic, A.; Jonjic, S.; Widera, M.; Ciesek, S.; Poehlmann, S.; Landthaler, M.; Cicin-Sain, L.
10.1101/2022.11.25.517953 — immunology — Posted on 2024-02-15
2322 Neural Circuit Revision in Retinal Remodeling, A Pathoconnectomics Approach
Pfeiffer, R. L.; Dahal, J.; Sigulinsky, C. L.; Anderson, J. R.; Barrera, I. A.; Yang, J.-H.; Haddadin, O.; Houser, A. R.; Garcia, J. C.; Jones, B. W.
10.1101/2024.02.14.580149 — neuroscience — Posted on 2024-02-15
2323 Functional specialization of Arabidopsis VEL polymerization domains in the switch to Polycomb silencing
Schulten, A.; Jang, G.-J.; Payne-Dwyer, A.; Nielsen, M. L.; Bienz, M.; Leake, M. C.; Dean, C.
10.1101/2024.02.15.580496 — plant biology — Posted on 2024-02-15
2324 A systematic quantitative approach comprehensively defines domain-specific functional pathways linked to Schizosaccharomyces pombe heterochromatin regulation
Muhammad, A.; Sarkadi, Z.; van Emden, T. S.; Mazumder, A.; Capella, M.; Fekete, G.; Sreechakram, V. N. S.; Al-Sady, B.; Papp, B.; Barrales, R. R.; Braun, S. J.
10.1101/2024.02.13.579970 — genomics — Posted on 2024-02-15
2326 Potent pollen gene regulation by DNA glycosylases in maize
Zeng, Y.; Somers, J.; Bell, H. S.; Dawe, R. K.; Fowler, J. E.; Nelms, B.; Gent, J. I.
10.1101/2024.02.13.580204 — genetics — Posted on 2024-02-15
2329 Leaf functional trait evolution and its putative climatic drivers in African Coffea species
Hendrickx, A.; Hatangi, Y.; Honnay, O.; Janssens, S. B.; Stoffelen, P.; Vandelook, F.; Depecker, J.
10.1101/2024.02.13.580072 — evolutionary biology — Posted on 2024-02-15
2330 Phylotranscriptomics reveals convergent behavioral evolution associated with shared and unique mechanisms in cavity-nesting songbirds
Lipshutz, S. E.; Hibbins, M. S.; Bentz, A. B.; Buechlin, A. M.; Empson, T. A.; George, E. M.; Hauber, M. E.; Rusch, D. B.; Schelsky, W. M.; Thomas, Q. K.; Torneo, S. J.; Turner, A. M.; Wolf, S. E.; Woodruff, M. J.; Hahn, M. W.; Rosvall, K. A.
10.1101/2024.02.13.580205 — evolutionary biology — Posted on 2024-02-15
2331 Multiple horizontal mini-chromosome transfers drive genome evolution of clonal blast fungus lineages
Barragan, A. C.; Latorre, S. M.; Malmgren, A.; Harant, A.; Win, J.; Sugihara, Y.; Burbano, H. A.; Kamoun, S.; Langner, T.
10.1101/2024.02.13.580079 — evolutionary biology — Posted on 2024-02-15
2332 Evolutionary genomics reveals variation in structure and genetic content implicated in virulence and lifestyle in the genus Gaeumannomyces
Hill, R.; Grey, M.; Olivera Fedi, M.; Smith, D. P.; Ward, S. J.; Canning, G.; Irish, N.; Smith, J.; McMillan, V.; Hammond, J.; Osborne, S.-J.; Chancellor, T.; Swarbreck, D.; Hall, N.; Palma-Guerrero, J.; Hammond-Kosack, K. E.; McMullan, M.
10.1101/2024.02.15.580261 — evolutionary biology — Posted on 2024-02-15
2338 Decision support for managing an invasive pathogen through efficient clean seed systems: Cassava mosaic disease in Southeast Asia
Andersen Onofre, K.; Delaquis, E.; Newby, J.; de Haan, S.; Thuy, C. T. L.; Minato, N.; Legg, J.; Cuellar, W.; Alcala Briseno, R.; Garrett, K. A.
10.1101/2024.02.13.580210 — ecology — Posted on 2024-02-15
2341 Intraspecific diversity in thermal performance determines phytoplankton ecological niche
Krinos, A. I.; Shapiro, S. K.; Li, W.; Haley, S. T.; Dyhrman, S. T.; Dutkiewicz, S.; Follows, M. J.; Alexander, H.
10.1101/2024.02.14.580366 — ecology — Posted on 2024-02-15
2343 Characterization of Reconstructed Human Epidermis in a Chemically-defined, Animal Origin-free Cell Culture System
Bajsert, J.; De Glas, V.; Faway, E.; Lambert de Rouvroit, C.; Perez-Aso, M.; Cook, P. W.; Poumay, Y.
10.1101/2024.02.13.580080 — cell biology — Posted on 2024-02-15
2344 A ratiometric ER calcium sensor for quantitative comparisons across cell types and subcellular regions
Farrell, R. J.; Bredvik, K. G.; Hoppa, M. B.; Hinnegan, S. T.; Brown, T. A.; Ryan, T. A.
10.1101/2024.02.15.580492 — cell biology — Posted on 2024-02-15
2346 Truncated NLRC5 isoforms in human placenta: expression, regulation by miR-218-5p, and function in trophoblasts
Shan, Y.; O'Brian, J.; Nadeem, L.; Dunk, C.; Chen, Y.; Brkic, J.; Hayder, H.; Lye, S. J.; Peng, C.
10.1101/2024.02.13.580136 — cell biology — Posted on 2024-02-15
2347 Characterization of a new lacrimal gland cell line in 2D and 3D cell culture models
Gleixner, S.; Zahn, I.; Dietrich, J.; Singh, S.; Drobny, A.; Schneider, Y.; Schwendner, R.; Socher, E.; Blavet, N.; Brauer, L.; Gostian, A.-O.; Balk, M.; Schulze-Tanzil, G.; Gunther, C.; Paulsen, F.; Arnold, P.
10.1101/2024.02.13.580096 — cell biology — Posted on 2024-02-15
2348 Cathepsin B regulates ovarian reserve quality and quantity via mitophagy by modulating IGF1R turnover.
Mohanty, A.; Kumari, A.; Kumar. S, L.; Kumar, A.; Birajdar, P.; Beniwal, R.; Athar, M.; Kumar P, K.; Prasada Rao, H.
10.1101/2024.02.14.580410 — cell biology — Posted on 2024-02-15
2351 Exact centriole counts are critical for B cell development but not function
Schapfl, M. A.; LoMastro, G. M.; Braun, V. Z.; Hirai, M.; Levine, M. S.; Kiermaier, E.; Labi, V.; Holland, A. J.; Villunger, A.
10.1101/2024.02.14.580240 — cell biology — Posted on 2024-02-15
2353 The transmembrane protein Syndecan regulates stem cell nuclear properties and cell maintenance.
Eldridge-Thomas, B. L.; Bohere, J. G.; Roubinet, C.; Barthelemy, A.; Samuels, T. J.; Karam Teixeira, F.; Kolahgar, G.
10.1101/2024.02.15.580237 — cell biology — Posted on 2024-02-15
2355 Derepression of transposable elements enhances interferon beta signaling and stem/progenitor cell activity after proton irradiation.
Cinat, D.; van der Wal, R.; Baanstra, M.; Gamez, A. A. S.; Jellema-de Bruin, A.; van Goethem, M.-J.; van Vugt, M.; Barazzuol, L.; Coppes, R. P.
10.1101/2024.02.14.580306 — cell biology — Posted on 2024-02-15
2357 Immune escape of Omicron lineages BA.1, BA.2, BA.5.1, BQ.1, XBB.1.5, EG.5.1 and JN.1.1 after vaccination, infection and hybrid immunity
Bekliz, M.; Essaidi-Laziosi, M.; Adea, K.; Hosszu-Fellous, K.; Alvarez, C.; Bellon, M.; Sattonnet-Roche, P.; Puhach, O.; Dbeissi, D.; Zaballa, M. E.; Stringhini, S.; Guessous, I.; Vetter, P.; Eberhardt, C. S.; Kaiser, L.; Eckerle, I.
10.1101/2024.02.14.579654 — microbiology — Posted on 2024-02-15
2358 Emergence and spread of SARS-CoV-2 variants from farmed mink to humans and back during the epidemic in Denmark, June-November 2020.
Rasmussen, T. B.; Qvesel, A. G.; Pedersen, A. G.; Olesen, A. S.; Fonager, J.; Rasmussen, M.; Sieber, R. N.; Stegger, M.; Artavia, F. F. C.; Thuesen, E. R.; Goedknegt, M. J. F.; Lohse, L.; Mortensen, S.; Fomsgaard, A.; Boklund, A. E.; Botner, A.; Belsham, G. J.
10.1101/2024.02.13.580053 — microbiology — Posted on 2024-02-15
2360 Presynaptic Nrxn3 is essential for ribbon-synapse assembly in hair cells
Jukic, A.; Lei, Z.; Cebul, E. R.; Pinter, K.; Mosqueda, N.; David, S.; Tarchini, B.; Kindt, K. S.
10.1101/2024.02.14.580267 — neuroscience — Posted on 2024-02-15
2361 Multi-species community platform for comparative neuroscience in teleost fish
Vohra, S.; Herrera, K.; Tavhelidse-Suck, T.; Wittbrodt, J.; Knoblich, S.; Seleit, A.; Aulehla, A.; Boulanger-Weill, J.; Chambule, S.; Aspiras, A.; Santoriello, C.; Fishman, M. C.; Hege, H.-C.; Baum, D.; Engert, F.; Isoe, Y.
10.1101/2024.02.14.580400 — neuroscience — Posted on 2024-02-15
2363 Thermally activated antibiotic production by probiotic bacteria for pathogen elimination
Dey, S.; Seyfert, C. E.; Fink-Straube, C.; Kany, A. M.; Mueller, R.; Sankaran, S.
10.1101/2024.02.13.579303 — bioengineering — Posted on 2024-02-15
2368 TSC22D, WNK and NRBP gene families exhibit functional buffering and evolved with Metazoa for macromolecular crowd sensing
Xiao, Y.-X.; Lee, S. Y.; Uribe, M. A.; Samson, R.; Au, A.; Yukti, K.; Liu, Z.; Cheng, R.; Aulakh, K.; Wei, J.; Farias, A. G.; Reilly, T.; Habsid, A.; Brown, K.; Chan, K.; Mero, P.; Huang, J. Q.; Billmann, M.; Rahman, M.; Myers, C.; Andrews, B.; Youn, J.-Y.; Yip, C.; Rotin, D.; Derry, B.; Forman-Kay, J.; moses, a.; Iva, P.; Gingras, A. C.; Moffat, J.
10.1101/2024.02.13.579840 — cell biology — Posted on 2024-02-15
2369 In-situ architecture of the human prohibitin complex
Lange, F.; Ratz, M.; Dohrke, J.-N.; Wenzel, D.; Ilgen, P.; Riedel, D.; Jakobs, S.
10.1101/2024.02.14.579514 — cell biology — Posted on 2024-02-15
2370 DFCP1 is a Regulator of ATGL-mediated Lipid Droplet Lipolysis
Ismail, V.; Schuetz, M.; Castillo-Badillo, J.; Naismith, T.; Kast, D. J.
10.1101/2024.02.14.580382 — cell biology — Posted on 2024-02-15
2374 Chlamydomonas cells transition through distinct Fe nutrition stages within 48 h of transfer to Fe-free medium
Liu, H. W.; Urzica, E. I.; Gallaher, S. D.; Blaby-Haas, C. E.; Iwai, M.; Schmollinger, S.; Merchant, S. S.
10.1101/2024.02.13.579691 — plant biology — Posted on 2024-02-15
2375 Leaf abaxial and adaxial surfaces differentially affect plant-fungal pathogen interactions
Caseys, C.; Muhich, A. J.; Vega, J.; Ahmed, M.; Hopper, A.; Kelly, D.; Kim, S.; Madrone, M.; Plaziak, T.; Wang, M.; Kliebenstein, D.
10.1101/2024.02.13.579726 — plant biology — Posted on 2024-02-15
2377 The ELF3-BBX24/BBX25-PIF4 module controls thermosensory growth in Arabidopsis
Malakar, B. C.; Singh, S.; Garhwal, V.; Upadhyaya, G.; Chandramohan, R.; Gangappa, S. N.
10.1101/2024.02.14.580362 — plant biology — Posted on 2024-02-15
2380 Differential GTP-dependent in-vitro polymerization of recombinant Physcomitrella FtsZ proteins
Milferstaedt, S. W. L.; Joest, M.; Hoernstein, S. N. W.; Bohlender, L. L.; Oezdemir, B.; van der Does, C.; Decker, E. L.; Reski, R.
10.1101/2024.02.14.580282 — plant biology — Posted on 2024-02-15
2383 Cell2Sentence: Teaching Large Language Models the Language of Biology
Levine, D.; Rizvi, S. A.; Levy, S.; Pallikkavaliyaveetil, N.; Chen, X.; Zhang, D.; Ghadermarzi, S.; Wu, R.; Zhang, Z.; Vrkic, I.; Zhong, A.; Raskin, D.; Han, I.; Fonseca, A.; Ortega Caro, J.; Karbasi, A.; Dhodapkar, R. M.; van Dijk, D.
10.1101/2023.09.11.557287 — bioinformatics — Posted on 2024-02-15
2384 Ultra-sensitive water contaminant detection with transcription factor interfaced microcantilevers
Agarwal, D. K.; Lucci, T. J.; Jung, J. K.; Shekhawat, G. S.; Lucks, J. B.; Dravid, V. P. B.
10.1101/2024.02.01.578376 — synthetic biology — Posted on 2024-02-15
2386 A programmable arthritis-specific receptor for guided articular cartilage regenerative medicine
Walton, B. L.; Shattuck-Brandt, R.; Hamann, C. A.; Tung, V. W.; Colazo, J. M.; Brand, D. D.; Hasty, K. A.; Duvall, C. L.; Brunger, J. M.
10.1101/2024.01.31.578281 — bioengineering — Posted on 2024-02-15
2387 A genetically-encoded fluorescent biosensor for visualization of acetyl-CoA in live cells
Smith, J. J.; Valentino, T. R.; Ablicki, A. H.; Banerjee, R.; Colligan, A. R.; Eckert, D. M.; Desjardins, G. A.; Diehl, K. L.
10.1101/2023.12.31.573774 — biochemistry — Posted on 2024-02-15
2389 Quantitative pathogenicity and host adaptation in a fungal plant pathogen revealed by whole-genome sequencing
AMEZROU, R.; DUCASSE, A.; COMPAIN, J.; LAPALU, N.; PITARCH, A.; DUPONT, L.; CONFAIS, J.; GOYEAU, H.; KEMA, G. H.; CROLL, D.; AMSELEM, J.; SANCHEZ-VALLET, A.; MARCEL, T. C.
10.1101/2022.12.23.521735 — genomics — Posted on 2024-02-15
2391 Integrated multimodal cell atlas of Alzheimer's disease
Gabitto, M. I.; Travaglini, K. J.; Rachleff, V. M.; Kaplan, E. S.; Long, B.; Ariza, J.; Ding, Y.; Mahoney, J. T.; Dee, N.; Goldy, J.; Melief, E. J.; Agrawal, A.; Kana, O.; Zhen, X.; Barlow, S. T.; Brouner, K.; Campos, J.; Campos, J.; Carr, A. J.; Casper, T.; Chakrabarty, R.; Clark, M.; Cool, J.; Dalley, R.; Darvas, M.; Ding, S.-L.; Dolbeare, T.; Egdorf, T.; Esposito, L.; Ferrer, R.; Fleckenstein, L. E.; Gala, R.; Gary, A.; Gelfand, E.; Gloe, J.; Guilford, N.; Guzman, J.; Hirschstein, D.; Ho, W.; Hupp, M.; Jarksy, T.; Johansen, N.; Kalmbach, B. E.; Keene, L. M.; Khawand, S.; Kilgore, M.; Kirkla
10.1101/2023.05.08.539485 — genomics — Posted on 2024-02-15
2394 Comparative transcriptomics reveal a novel tardigrade specific DNA binding protein induced in response to ionizing radiation
Anoud, M.; Delagoutte, E.; Helleu, Q.; Brion, A.; Duvernois-Berthet, E.; As, M.; Marques, X.; Lamribet, K.; Senamaud, C.; Jourdren, L.; Adrait, A.; Heinrich, S.; Toutirais, G.; Hamlaoui, S.; Gropplero, G.; Ponger, L.; Geze, M.; Blugeon, C.; Coute, Y.; Guidetti, R.; Rebecchi, L.; Giovannangeli, C.; De Cian, A.; Concordet, J.-P.
10.1101/2023.09.08.556854 — molecular biology — Posted on 2024-02-15
2395 Influence of insulin sensitivity on food cue evoked functional brain connectivity in children
Semeia, L.; Veit, R.; Zhao, S.; Luo, S.; Angelo, B.; Birkenfeld, A. L.; Preissl, H.; Xiang, A. H.; Kullmann, S.; Page, K. A.
10.1101/2024.02.12.579924 — neuroscience — Posted on 2024-02-15
2397 Chronic activation of a negative engram induces behavioral and cellular abnormalities
Jellinger, A. L.; Suthard, R. L.; Yuan, B.; Surets, M.; Ruesch, E. A.; Caban, A. J.; Liu, X. S.; Shpokayte, M.; Ramirez, S.
10.1101/2023.11.15.567268 — neuroscience — Posted on 2024-02-15
2399 M2M-InvNet: Human Motor Cortex Mapping from Multi-Muscle Response Using TMS and Generative 3D Convolutional Network
Akbar, M. N.; Yarossi, M.; Rampersad, S.; Lockwood, K.; Masoomi, A.; Tunik, E.; Brooks, D.; Erdogmus, D.
10.1101/2022.07.22.501062 — neuroscience — Posted on 2024-02-15
2400 Psilocybin induces dose-dependent changes in functional network organization in rat cortex
Silverstein, B. H.; Kolbman, N.; Nelson, A.; Liu, T.; Guzzo, P.; Gilligan, J.; Lee, U.; Mashour, G. A.; Vanini, G.; Pal, D.
10.1101/2024.02.09.579718 — neuroscience — Posted on 2024-02-15
2401 A dual function of the IDA peptide in regulating cell separation and modulating plant immunity at the molecular level
Lalun, V. O.; Breiden, M.; Galindo-Trigo, S.; Smakowska-Luzan, E.; Simon, R.; Butenko, M. A.
10.1101/761346 — plant biology — Posted on 2024-02-15
2402 A shade-responsive microProtein in the Arabidopsis ATHB2 gene regulates elongation growth and root development
Edwards, A. K.; Chiurazzi, M. J.; Blaakmeer, A.; Vittozzi, Y.; Sharma, A.; Matton, S.; Kruusvee, V.; Straub, D.; Sessa, G.; Carabelli, M.; Morelli, G.; Wenkel, S.
10.1101/2024.02.01.578400 — plant biology — Posted on 2024-02-15
2404 Encapsulation of AAVs into protein vault nanoparticles as a novel solution to gene therapy's neutralizing antibody problem
Collins, L. T.; Beatty, W.; Moyo, B.; Alves-Bezerra, M.; Hurley, A.; Lou, Q.; Zhou, Z. H.; Lagor, W.; Bao, G.; Ponnazhagan, S.; McNally, R.; Rome, L.; Curiel, D.
10.1101/2023.11.29.569229 — bioengineering — Posted on 2024-02-15
2405 Expanding the Drosophila toolkit for dual control of gene expression
Zirin, J.; Jusiak, B.; Lopes, R.; Ewen-Campen, B.; Bosch, J.; Risbeck, A.; Forman, C.; Villalta, C.; Hu, Y.; Perrimon, N.
10.1101/2023.08.15.553399 — genetics — Posted on 2024-02-15
2406 Catching more air: A method to spatially quantify aerial triazole resistance in Aspergillus fumigatus
Kortenbosch, H. H.; van Leuven, F.; van den Heuvel, C.; Schoustra, S. S.; Zwaan, B. J.; Snelders, E.
10.1101/2022.11.03.515058 — microbiology — Posted on 2024-02-15
2407 Unique growth and morphology properties of Clade 5 Clostridioides difficile strains revealed by single-cell time-lapse microscopy
Ribis, J. W.; Nieto-Acuna, C. A.; Dong, Q.; DiBenedetto, N.; Mehra, A.; Nagawa, I. L.; El Meouche, I.; Aldridge, B. B.; Dunlop, M. J.; Tamayo, R.; Singh, A.; Shen, A.
10.1101/2024.02.13.580212 — microbiology — Posted on 2024-02-15
2408 Mast cell activation disrupts interactions between endothelial cells and pericytes during early life allergic asthma
Joulia, R.; Puttur, F.; Stölting, H.; Entwistle, L. J.; Voitovich, A.; Al-Sahaf, M.; Bonner, K.; Scotney, E.; Molyneaux, P.; Hewitt, R. J.; Walker, S. A.; Yates, L. L.; Saglani, S.; Lloyd, C. M.
10.1101/2023.03.07.529253 — immunology — Posted on 2024-02-15
2411 Two distinct mechanisms for Nav1.7 null analgesia
Kanellopoulos, A.; Tian, N.; Cox, J. J.; Zhao, J.; Woods, G.; Wood, J.
10.1101/2024.02.12.579826 — neuroscience — Posted on 2024-02-15
2412 Fractal cycles of sleep: a new aperiodic activity-based definition of sleep cycles
Rosenblum, Y.; Jafarzadeh Esfahani, M.; Adelhöfer, N.; Zerr, P.; Furrer, M.; Huber, R.; Steiger, A.; Zeising, M.; Horvath, C. G.; Schneider, B.; Bodizs, R.; Dresler, M.
10.1101/2023.07.04.547323 — neuroscience — Posted on 2024-02-15
2413 Multi-study fMRI outlooks on subcortical BOLD responses in the stop-signal paradigm
Isherwood, S. J. S.; Kemp, S. A.; Miletic, S.; Stevenson, N.; Bazin, P.-L.; Forstmann, B.
10.1101/2023.06.06.543900 — neuroscience — Posted on 2024-02-15
2415 Self-perceived middle-distance race pace is faster in Advanced Footwear Technology spikes
Bertschy, M.; Rodrigo Carranza, V.; Wilkie, E. W. C.; Healey, L. A.; Noble, J.; Albert, W. J.; Hoogkamer, W.
10.1101/2023.10.25.564056 — physiology — Posted on 2024-02-15
2416 mitoBKCa is functionally expressed in murine and human breast cancer cells and potentially contributes to metabolic reprogramming
Bischof, H.; Maier, S.; Koprowski, P.; Kulawiak, B.; Burgstaller, S.; Jasinska, J.; Serafimov, K.; Zochowska, M.; Gross, D.; Schroth, W.; Matt, L.; Juarez Lopez, D. A.; Zhang, Y.; Bonzheim, I.; Büttner, F. A.; Fend, F.; Schwab, M.; Birkenfeld, A. L.; Malli, R.; Lämmerhofer, M.; Bednarczyk, P.; Szewczyk, A.; Lukowski, R.
10.1101/2023.10.02.560571 — cancer biology — Posted on 2024-02-15
2417 SpaCeNet: Spatial Cellular Networks from omics data
Schrod, S.; Lück, N.; Lohmayer, R.; Solbrig, S.; Völkl, D.; Wipfler, T.; Shutta, K. H.; Guebila, M. B.; Schäfer, A.; Beissbarth, T.; Zacharias, H. U.; Oefner, P. J.; Quackenbush, J.; Altenbuchinger, M.
10.1101/2022.09.01.506219 — bioinformatics — Posted on 2024-02-15
2418 Movi: a fast and cache-efficient full-text pangenome index
Zakeri, M.; Brown, N. K.; Ahmed, O. Y.; Gagie, T.; Langmead, B.
10.1101/2023.11.04.565615 — bioinformatics — Posted on 2024-02-15
2419 Cross-species single-cell annotation with orthologous marker gene groups
Chau, T.; Timilsena, P. R.; Kundu, S.; Bathala, S. P.; Bargmann, B.; Li, S.
10.1101/2023.06.18.545471 — bioinformatics — Posted on 2024-02-15
2421 Non-targeted isomer-sensitive N-glycome analysis reveals new layers of organ-specific diversity in mice.
Helm, J.; Mereiter, S.; Oliveira, T.; Gattinger, A.; Markovitz, D. M.; Penninger, J. M.; Altmann, F.; Stadlmann, J.
10.1101/2022.09.19.508483 — biochemistry — Posted on 2024-02-15
2425 Unraveling the Genomic Diversity and Admixture History of Captive Tigers in the United States
Armstrong, E. E.; Mooney, J. A.; Solari, K. A.; Kim, B. Y.; Barsh, G. S.; Grant, V. B.; Greenbaum, G.; Kaelin, C. B.; Panchenko, K.; Pickrell, J. K.; Rosenberg, N.; Ryder, O. A.; Yokoyama, T.; Ramakrishnan, U.; Petrov, D. A.; Hadly, E. A.
10.1101/2023.06.19.545608 — evolutionary biology — Posted on 2024-02-15
2426 Using artificial intelligence to document the hidden RNA virosphere
Hou, X.; He, Y.; Fang, P.; Mei, S.-Q.; Xu, Z.; Wu, W.-C.; Tian, J.-H.; Zhang, S.; Zeng, Z.-Y.; Gou, Q.-Y.; Xin, G.-Y.; Le, S.-J.; Xia, Y.-Y.; Zhou, Y.-L.; Hui, F.-M.; Pan, Y.-F.; Eden, J.-S.; Yang, Z.-H.; Han, C.; Shu, Y.-L.; Guo, D.; Li, J.; Holmes, E. C.; Li, Z.-R.; Shi, M.
10.1101/2023.04.18.537342 — microbiology — Posted on 2024-02-15
2429 Rate of brain aging associates with future executive function in Asian children and older adults
Cheng, S. F.; Yue, W. L.; Ng, K. K.; Qian, X.; Liu, S.; Tan, T. W. K.; Nguyen, K.-N.; Leong, R. L. F.; Hilal, S.; Cheng, C.-Y.; Tan, A. P.; Law, E. C.; Gluckman, P. D.; Chen, C. L.-H.; Chong, Y. S.; Meaney, M. J.; Chee, M.; Yeo, B. T. T.; Zhou, J. H.
10.1101/2023.11.27.568184 — neuroscience — Posted on 2024-02-15
2433 Points2Regions: Fast, interactive clustering of imaging-based spatial transcriptomics data
Andersson, A.; Behanova, A.; Windhager, J.; Avenel, C.; Malmberg, F.; Wählby, C.
10.1101/2022.12.07.519086 — bioinformatics — Posted on 2024-02-15
2437 Metaplastic tuft cells transdifferentiate to neural-like progenitor cells in the progression of pancreatic cancer
Salas-Escabillas, D. J.; Hoffman, M. T.; Moore, J. S.; Brender, S. M.; Wen, H.-J.; Benitz, S.; Davis, E. T.; Long, D.; Wombwell, A. M.; Steele, N. G.; Sears, R. C.; Matsumoto, I.; DelGiorno, K. E.; Crawford, H. C.
10.1101/2024.02.12.579982 — cancer biology — Posted on 2024-02-14
2440 Maramycin, a cytotoxic isoquinolinequinone terpenoid produced through heterologous expression of a bifunctional indole prenyltransferase /tryptophan indole-lyase in S. albidoflavus
Maleckis, M.; Wibowo, M.; Williams, S. E.; Gotfredsen, C. H.; Sigrist, R.; Souza, L. D. O.; Cowled, M. S.; Charusanti, P.; Gren, T.; Saha, S.; Moreira, J. M. A.; Weber, T.; Ding, L.
10.1101/2024.02.14.580309 — bioengineering — Posted on 2024-02-14
2442 Surveying the landscape of RNA isoform diversity and expression across 9 GTEx tissues using long-read sequencing data
Page, M. L.; Aguzzoli Heberle, B.; Brandon, J. A.; Wadsworth, M.; Gordon, L. A.; Nations, K. A.; Ebbert, M. T. W.
10.1101/2024.02.13.579945 — genomics — Posted on 2024-02-14
2443 Uncovering the simple adhesive strategy of the Toxoplasma parasite for high-speed motility
Vigetti, L.; Touquet, B.; Debarre, D.; Rose, T.; Bureau, L.; Abdallah, D.; Dubacheva, G.; Tardieux, I.
10.1101/2024.02.13.580110 — cell biology — Posted on 2024-02-14
2444 Central Role for Glycolysis and Fatty Acids in LH-responsive Progesterone Synthesis
Przygrodzka, E.; Binderwala, F.; Powers, R.; McFee, R. M.; Cupp, A. S.; Wood, J. R.; Davis, J. S.
10.1101/2024.02.14.580329 — molecular biology — Posted on 2024-02-14
2445 Translational response to mitochondrial stresses is orchestrated by tRNA modifications.
Rashad, S.; Al-Mesitef, S.; Mousa, A.; Zhou, Y.; Ando, D.; Sun, G.; Fukuuchi, T.; Iwasaki, Y.; Xiang, J.; Byrne, S. R.; Sun, J.; Maekawa, M.; Saigusa, D.; Begley, T.; Dedon, P.; Niizuma, K.
10.1101/2024.02.14.580389 — molecular biology — Posted on 2024-02-14
2446 A single amino acid in the Salmonella effector SarA/SteE triggers supraphysiological activation of STAT3 for anti-inflammatory target gene expression
Gaggioli, M. R.; Jones, A. G.; Panagi, I.; Washington, E. J.; Loney, R. E.; Muench, J. H.; Brennan, R. G.; Thurston, T. L. M.; Ko, D. C.
10.1101/2024.02.14.580367 — molecular biology — Posted on 2024-02-14
2447 Protein UFMylation regulates early events of ribosomal DNA double-stranded break response
Panichnantakul, P.; Aguilar, L. C.; Daynard, E.; Guest, M.; Peters, C.; Vogel, J.; Oeffinger, M.
10.1101/2024.02.14.580383 — molecular biology — Posted on 2024-02-14
2449 Shifting to biology promotes highly efficient iron removal in groundwater filters
Mueller, S.; Corbera-Rubio, F.; Schoonenberg-Kegel, F.; Laureni, M.; van Loosdrecht, M.; van Halem, D.
10.1101/2024.02.14.580244 — microbiology — Posted on 2024-02-14
2451 Paired metagenomic and chemical evaluation of an aflatoxin contaminated dog kibble
Ottesen, A.; Kocurek, B. J.; Reed, E.; Commichaux, S.; Mammel, M. K.; Ramachandran, P.; McDermott, P. F.; Flannery, B. M.; Strain, E. A.
10.1101/2024.02.14.580305 — microbiology — Posted on 2024-02-14
2454 SbPIP2 Mediated Improvements in Plant Resilience: Physiological and Molecular Insights into Abiotic Stress Response
Patel, J.; Khatri, K.; Gupta, N. K.; Maniar, J.; Khandwal, D.; Choudhary, B.; Phillips, D.; Jones, H. D.; Mishra, A.
10.1101/2024.02.13.580036 — plant biology — Posted on 2024-02-14
2456 Single-cell Masked Autoencoder: An Accurate and Interpretable Automated Immunophenotyper
Kim, J.; Ionita, M.; Lee, M.; McKeague, M. L.; Pattekar, A.; Painter, M. M.; Wagenaar, J.; Truong, V.; Norton, D. T.; Mathew, D.; Nam, Y.; Apostolidis, S. A.; Clendenin, C.; Orzechowski, P.; Jung, S.-H.; Woerner, J.; Ittner, C. A. G.; Turner, A. P.; Esperanza, M.; Dunn, T. G.; Mangalmurti, N. S.; Reilly, J. P.; Meyer, N. J.; Calfee, C. S.; Liu, K. D.; Matthy, M. A.; Swigart, L. B.; Burnham, E. L.; McKeehan, J.; Gandotra, S.; Russel, D. W.; Gibbs, K. W.; Thomas, K. W.; Barot, H.; Greenplate, A. R.; Wherry, E. J.; Kim, D.
10.1101/2024.02.13.580114 — bioinformatics — Posted on 2024-02-14
2457 Virus-free CRISPR knock-in of a chimeric antigen receptor into KLRC1 generates potent GD2-specific natural killer cells
Shankar, K.; Zingler-Hoslet, I.; Shi, L.; Katta, V.; Russell, B. E.; Tsai, S. Q.; Capitini, C. M.; Saha, K.
10.1101/2024.02.14.580371 — bioengineering — Posted on 2024-02-14
2458 Mapping protein-metabolite interactions in E. coli by integrating chromatographic techniques and co-fractionation mass spectrometry.
Wagner, M. M.; Kang, J.; Mercado, C.; Thirumlaikumar, V. P.; Gorka, M.; Zillmer, H.; Guo, J.; Minen, R. I.; Plecki, C. F.; Dehesh, K.; Schroeder, F. C.; Walther, D.; Skirycz, A.
10.1101/2024.02.14.580258 — biochemistry — Posted on 2024-02-14
2459 Development of subunit selective proteasome substrates for Schistosoma species
Jiang, Z.; Da Silva, E. B.; Liu, C.; Fajtova, P.; Liu, L. J.; El-Sakkary, N.; Skinner, D.; Syed, A.; Wang, S. C.; Caffrey, C. J.; O'Donoghue, A. J.
10.1101/2024.02.13.580161 — biochemistry — Posted on 2024-02-14
2460 Structural basis of Cdk7 activation by dual T-loop phosphorylation
Duster, R.; Anand, K.; Binder, S. C.; Schmitz, M.; Gatterdam, K.; Fisher, R. P.; Geyer, M.
10.1101/2024.02.14.580246 — biochemistry — Posted on 2024-02-14
2461 Unique growth and morphology properties of Clade 5 Clostridioides difficile strains revealed by single-cell time-lapse microscopy
Ribis, J. W.; Nieto-Acuna, C. A.; Dong, Q.; DiBenedetto, N.; Mehra, A.; Nagawa, I. L.; El Meouche, I.; Aldridge, B. B.; Dunlop, M. J.; Tamayo, R.; Singh, A.; Shen, A.
10.1101/2024.02.13.580212 — microbiology — Posted on 2024-02-14
2463 Complex carbohydrate utilization by gut bacteria modulates host food preference
Yu, K. B.; Son, C.; Chandra, A.; Paramo, J.; Novoselov, A.; Ozcan, E.; Kazmi, S.; Lum, G.; Lopez-Romero, A.; Lynch, J.; Hsiao, E. Y.
10.1101/2024.02.13.580152 — microbiology — Posted on 2024-02-14
2465 Anti-capsule human monoclonal antibodies protect against hypervirulent and pandrug-resistant Klebsiella pneumoniae
Roscioli, E.; Zucconi Galli Fonseca, V.; Bosch, S. S.; Paciello, I.; Maccari, G.; Batani, G.; Stazzoni, S.; Cardinali, G.; Tiseo, G.; Giordano, C.; Shen, Y.; Capoccia, L.; Ridelfi, M.; Troisi, M.; Manganaro, N.; Mugnaini, C.; Cardamone, D.; De Santi, C.; Ciabattini, A.; Cerofolini, L.; Fragai, M.; Licastro, D.; Nicolau, D. P.; Abdelraouf, K.; Barnini, S.; Menichetti, F.; Falcone, M.; Sala, C.; Kabanova, A.; Rappuoli, R.
10.1101/2024.02.14.580141 — microbiology — Posted on 2024-02-14
2466 Hosts Manipulate Lifestyle Switch and Pathogenicity Heterogeneity of Opportunistic Pathogens in the Single-cell Resolution
Wang, Z.; Li, S.; Zhang, S.; Zhang, T.; Wu, Y.; Liu, A.; Wang, K.; Ji, X.; Cao, H.; Tan, E. K.; Wang, Y.; Wang, Y.; Liu, W.
10.1101/2024.02.14.580325 — microbiology — Posted on 2024-02-14
2468 The atypical antipsychotic aripiprazole alters the outcome of disseminated Candida albicans infections.
Reitler, P.; Regan, J.; DeJarnette, C.; Srivastava, A.; Carnahan, J. A.; Tucker, K. M.; Meibohm, B.; Peters, B. M.; Palmer, G. E.
10.1101/2024.02.13.580133 — microbiology — Posted on 2024-02-14
2470 Epigenome and early selection determine the tumour-immune evolutionary trajectory of colorectal cancer
Lakatos, E.; Gunasri, V.; Zapata, L.; Househam, J.; Heide, T.; Trahearn, N.; Swinyard, O.; Cisneros, L.; Lynn, C.; Mossner, M.; Kimberley, C.; Spiteri, I.; Cresswell, G. D.; Llibre-Palomar, G.; Mitchison, M.; Maley, C. C.; Jansen, M.; Rodriguez-Justo, M.; Bridgewater, J.; Baker, A.-M.; Sottoriva, A.; Graham, T. A.
10.1101/2024.02.12.579956 — cancer biology — Posted on 2024-02-14
2471 Disrupting CD38-driven T cell dysfunction restores sensitivity to cancer immunotherapy
Revach, O.-Y.; Cicerchia, A. M.; Shorer, O.; Petrova, B.; Anderson, S.; Park, J.; Chen, L.; Mehta, A.; Wright, S. J.; McNamee, N.; Tal-Mason, A.; Cattaneo, G.; Tiwari, P.; Xie, H.; Sweere, J. M.; Cheng, L.-C.; Sigal, N.; Enrico, E.; Miljkovic, M.; Evans, S. A.; Nguyen, N.; Whidden, M. E.; Srinivasan, R.; Spitzer, M. H.; Sun, Y.; Sharova, T.; Lawless, A.; Michaud, W. A.; Rasmussen, M. Q.; Fang, J.; Palin, C.; Chen, F.; Wang, X.; Ferrone, C. R.; Lawrence, D. P.; Sullivan, R. J.; Liu, D.; Sachdeva, U. M.; Sen, D. R.; Flaherty, K. T.; Manguso, R. T.; Bod, L.; Kellis, M.; Boland, G. M.; Yizhak, K.;
10.1101/2024.02.12.579184 — cancer biology — Posted on 2024-02-14
2473 Metal ion activation and DNA recognition by the Deinococcus radiodurans manganese sensor DR2539
Mota, C.; Webster, M.; Saidi, M.; Kapp, U.; Zubieta, C.; Giachin, G.; Manso, J. A.; de Sanctis, D.
10.1101/2024.02.12.579695 — biophysics — Posted on 2024-02-14
2477 DEEP LEARNING APPROACH FOR RENAL CELL CARCINOMA DETECTION,SUBTYPING, AND GRADING
Aziz, M. A.; Javadian, F.; Susheel, S.; Gopal, A.; Stegmaier, J.; Jose, A.
10.1101/2024.02.12.577550 — bioinformatics — Posted on 2024-02-14
2486 mTOR signaling regulates aberrant epithelial cell proliferative and migratory behaviors characteristic of airway mucous metaplasia in asthma
Kudrna, K.; Staab, E. B.; Eilers, E.; Thomes, P.; Maurya, S.; Brody, S. L.; Wyatt, T. A.; Bailey, K. L.; Dickinson, J. D.
10.1101/2024.02.12.579905 — cell biology — Posted on 2024-02-14
2487 Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire
Altman, P.; Ozorowski, G.; Stanfield, R.; Haakenson, J.; Appel, M.; Parren, M.; Lee, W.-H.; Sang, H.; Woehl, J.; Saye-Francisco, K.; Joyce, C.; Song, G.; Porter, K.; Landais, E.; Andrabi, R.; Wilson, I.; Ward, A.; Mwangi, W.; Smider, V.; Burton, D.; Sok, D.
10.1101/2024.02.13.580058 — immunology — Posted on 2024-02-14
2489 A Workflow for Improved Analysis of Cross-linking Mass Spectrometry Data Integrating Parallel Accumulation-Serial Fragmentation with MeroX and Skyline
Rojas Echeverri, J. C.; Hause, F.; Iacobucci, C.; Ihling, C. H.; Tanzler, D.; Shulman, N.; Riffle, M.; MacLean, B.; Sinz, A.
10.1101/2024.02.13.580038 — bioinformatics — Posted on 2024-02-14
2490 Targeted genotyping-by-sequencing of potato and software for imputation
Endelman, J. B.; Kante, M.; Lindqvist-Kreuze, H.; Kilian, A.; Shannon, L. M.; Caraza-Harter, M. V.; Vaillancourt, B.; Mailloux, K.; Hamilton, J. P.; Buell, C. R.
10.1101/2024.02.12.579978 — genomics — Posted on 2024-02-14
2492 Pathogen and pest risks to vegetatively propagated crops in humanitarian contexts: Geographic priorities for Cameroon and Ethiopia
Mouafo-Tchinda, R.; Etherton, B.; Plex Sula, A.; Andrade-Piedra, J.; Ogero, K.; Omondi, B. A.; McEwan, M.; Tene Tayo, P.; Harahagazwe, D.; Cherinet, M.; Gebeyehu, S.; Sperling, L.; Garrett, K. A.
10.1101/2024.02.12.580019 — ecology — Posted on 2024-02-14
2493 Emergence and spread of SARS-CoV-2 variants from farmed mink to humans and back during the epidemic in Denmark, June-November 2020.
Rasmussen, T. B.; Qvesel, A. G.; Pedersen, A. G.; Olesen, A. S.; Fonager, J.; Rasmussen, M.; Sieber, R. N.; Stegger, M.; Artavia, F. F. C.; Thuesen, E. R.; Goedknegt, M. J. F.; Lohse, L.; Mortensen, S.; Fomsgaard, A.; Boklund, A. E.; Botner, A.; Belsham, G. J.
10.1101/2024.02.13.580053 — microbiology — Posted on 2024-02-14
2494 Evaluation of a novel Tc-24 recombinant antigen ELISA for serologic testing for Trypanosoma cruzi in dogs
Mejia, R.; Verocai, G. G.; Mosley, I. A.; Zhan, B.; Vongthavaravat, L.; Busselman, R. E.; Hamer, S. A.
10.1101/2024.02.12.579969 — zoology — Posted on 2024-02-14
2497 ROS responsive Aux/IAA multimerization modulates auxin responses
Roy, D.; Mehra, P.; Mukkawar, V.; Clark, L.; Bellande, K.; Vermeer, J. E.; Arevallilo, R. M.; VERNOUX, T.; Sue ob, K.; Jones, A. R.; Bechtold, U.; Mullineaux, P. M.; Lilley, K.; Brown, A.; Bennett, M.; Sadanandom, A.
10.1101/2024.02.12.579961 — plant biology — Posted on 2024-02-14
2498 Ultraviolet attenuates centromere-mediated meiotic genome stability and alters gametophytic ploidy consistency in flowering plants
Fu, H.; Zhong, J.; Zhao, J.; Huo, L.; Wang, C.; Ma, D.; Pan, W.; Sun, L.; Ren, Z.-M.; Fan, T.; Wang, Z.; Wang, W.; Lei, X.; Yu, G.; Li, J.; Zhu, Y.; Geelen, D. N. V.; Liu, B.
10.1101/2024.02.12.579936 — plant biology — Posted on 2024-02-14
2500 Proteolytic Cleavage of the ENaC gamma Subunit: Impact Upon Na+ and K+ Handling
Ray, E. C.; Nickerson, A.; Sheng, S.; Carrisoza-Gaytan, R.; Lam, T.; Marciszyn, A.; Zhang, L.; Jordahl, A.; Bi, C.; Winfrey, A.; Kou, Z.; Gingras, S.; Kirabo, A.; Satlin, L. M.; Kleyman, T. R.
10.1101/2024.02.12.579964 — physiology — Posted on 2024-02-14
2505 Named Entity Recognition of Pharmacokinetic parameters in the scientific literature
Hernandez, F. G.; Nguyen, Q.; Smith, V. C.; Cordero, J. A.; Ballester, M. R.; Duran, M.; Sole, A.; Chotsiri, P.; Wattanakul, T.; Mundin, G.; Lilaonitkul, W.; Standing, J. F.; Kloprogge, F.
10.1101/2024.02.12.580001 — pharmacology and toxicology — Posted on 2024-02-14
2506 Tumor-localized interleukin-2 and interleukin-12 combine with radiation therapy to safely potentiate regression of advanced malignant melanoma in pet dogs
Stinson, J. A.; Barbosa, M. M. P.; Sheen, A.; Momin, N.; Fink, E.; Hampel, J.; Selting, K.; Kamerer, R.; Bailey, K. L.; Wittrup, K. D.; Fan, T. M.
10.1101/2024.02.12.579965 — cancer biology — Posted on 2024-02-14
2509 Deciphering Peptide-Protein Interactions via Composition-Based Prediction: A Case Study with Survivin/BIRC5
Anindya, A. L.; Olsson, T. N.; Jensen, M.; Garcia-Bonete, M.-J.; Wheatley, S.; Bokarewa, M.; Mezzasalma, S. A.; Katona, G.
10.1101/2024.02.12.579763 — bioinformatics — Posted on 2024-02-14
2510 Developing and Investigating a Nanovibration Intervention for the Prevention/Reversal of Bone Loss Following Spinal Cord Injury
Williams, J. A.; Campsie, P.; Gibson, R.; Johnson-Love, O.; Werber, A. S.; Sprott, M.; Meechan, R.; Huesa, C.; Windmill, J. F. C.; Purcell, M.; Coupaud, S.; Dalby, M. J.; Childs, P. G.; Riddell, J. S.; Reid, S.
10.1101/2024.02.12.578222 — bioengineering — Posted on 2024-02-14
2512 Controlling for polygenic genetic confounding in epidemiologic association studies
Zhao, Z.; Yang, X.; Miao, J.; Dorn, S.; Barcellos, S.; Fletcher, J.; Lu, Q.
10.1101/2024.02.12.579913 — genetics — Posted on 2024-02-14
2513 Translating Ethiopian potato seed networks: Identifying strategic intervention points for managing bacterial wilt and other diseases
Etherton, B.; Plex Sula, A.; Mouafo-Tchinda, R.; Kakuhenzire, R.; Kassaye, H.; Asfaw, F.; Kosmakos, V.; McCoy, R.; Xing, Y.; Yao, J.; Sharma, K.; Garrett, K. A.
10.1101/2024.02.12.579952 — ecology — Posted on 2024-02-14
2518 Skin Sensitisation Case Study: Comparison of Defined Approaches including OECD 497 Guidance
Hardy, B.; Ankli, P.; Parween, S.; Lopez, B.; Daligaux, P.; Mohoric, T.; Darde, T.; Chesne, C.; Stockman, N.; Boglari, C.; Poon, A.
10.1101/2024.02.12.579980 — pharmacology and toxicology — Posted on 2024-02-14
2520 NEKL-4 regulates microtubule stability and mitochondrial health in C. elegans ciliated neurons
Power, K. M.; Nguyen, K. C.; Silva, A.; Singh, S.; Hall, D. H.; Rongo, C.; Barr, M. M.
10.1101/2024.02.14.580304 — cell biology — Posted on 2024-02-14
2521 Caspase-2 kills cells with extra centrosomes
Rizzotto, D.; Vigorito, V.; Rieder, P.; Gallob, F.; Moretta, G. M.; Soratroi, C.; Riley, J.; Bellutti, F.; Li Veli, S.; Mattivi, A.; Lohmueller, M.; Herzog, S.; Bornhauser, B. C.; Jacotot, E. D.; Villunger, A.; Fava, L. L.
10.1101/2024.02.13.580097 — cell biology — Posted on 2024-02-14
2523 The effect of constitutive root isoprene emission on root phenotype and physiology under control and salt stress conditions
Bellucci, M.; Mostofa, M. G.; Weraduwage, S. M.; Xu, Y.; Abdelrahman, M.; De Gara, L.; Loreto, F.; Sharkey, T. D.
10.1101/2024.02.09.579703 — plant biology — Posted on 2024-02-14
2528 NOTUM-MEDIATED WNT SILENCING DRIVES EXTRAVILLOUS TROPHOBLAST CELL LINEAGE DEVELOPMENT
Shukla, V.; Irusta, A. M.; Varberg, K. M.; Kuna, M.; Iqbal, K.; Galligos, A. M.; Aplin, J. D.; Choudhury, R. H.; Okae, H.; Arima, T.; Soares, M. J.
10.1101/2024.02.13.579974 — developmental biology — Posted on 2024-02-14
2530 Trim66 paternal deficiency causes intrauterine overgrowth
Mielnicka, M.; Tabaro, F.; Sureka, R.; Acurzio, B.; Paoletti, R.; Scavizzi, F.; Raspa, M.; Crevenna, A. H.; Lapouge, K.; Remans, K.; Boulard, M.
10.1101/2024.02.12.579976 — developmental biology — Posted on 2024-02-14
2534 Early mechanisms of aortic failure in a zebrafish model for thoracic aortic dissection and rupture
Vanhooydonck, M.; Verlee, M.; Silva, M. S.; Pottie, L.; Boel, A.; Van Impe, M.; De Saffel, H.; Caboor, L.; Tapaneeyaphan, P.; Bonnin, A.; Segers, P.; De Clercq, A.; Willaert, A.; Syx, D.; Sips, P.; Callewaert, B.
10.1101/2024.02.12.580022 — developmental biology — Posted on 2024-02-14
2535 Mitigation of Fetal Irradiation Injury from Mid-Gestation Total Body Radiation with Mitochondrial-Targeted GS-Nitroxide JP4-039
Wu, Y. L.; Ghristodoulou, A. G.; Beumer, J. H.; Rigatti, L. H.; Fisher, R.; Ross, M.; Watkins, S.; Cortes, D. R. E.; Ruck, C.; Manzoor, S.; Wyman, S. K.; Stapleton, M. C.; Goetzman, E.; Bharathi, S.; Wipf, P.; Tan, T.; Eiseman, J. L.; Christner, S. M.; Guo, J.; Lo, C. W. Y.; Epperly, M. W.; Greenberger, J. S.
10.1101/2024.02.13.580105 — developmental biology — Posted on 2024-02-14
2540 Characterizing directional dynamics of semantic prediction based on inter-regional temporal generalization
Mamashli, F.; Khan, S.; Hatamimajoumerd, E.; Jas, M.; Uluc, I.; Lankinen, K.; Obleser, J.; Friederici, A. D.; Maess, B.; Ahveninen, J.
10.1101/2024.02.13.580183 — neuroscience — Posted on 2024-02-14
2545 Dissecting the contribution of vagal subcircuits in sepsis-induced brain dysfunctions.
Bourhy, L.; Moigneu, C.; Dupin, A.; Hecquet, E.; Levy, J.; Sharshar, T.; Lledo, P.-M.; Lepousez, G.
10.1101/2024.02.14.580156 — neuroscience — Posted on 2024-02-14
2547 The Lab Streaming Layer for Synchronized Multimodal Recording
Kothe, C.; Shirazi, S. Y.; Stenner, T.; Medine, D.; Boulay, C.; Crivich, M. I.; Mullen, T.; Delorme, A.; Makeig, S.
10.1101/2024.02.13.580071 — neuroscience — Posted on 2024-02-14
2550 DORSAL RAPHE NUCLEUS CONTROLS MOTIVATIONAL STATE TRANSITIONS IN MONKEYS
Priestley, L.; Chiew, M.; Shahdloo, M.; Mahmoodi, A.; Cheng, X.; Cleveland, R.; Rushworth, M.; Khalighinejad, N.
10.1101/2024.02.13.580224 — neuroscience — Posted on 2024-02-14
2552 Focused Ultrasound modulates dopamine in a mesolimbic reward circuit
Olaitan, G.; Ganesana, M.; Lynch, W. J.; Legon, W.; Venton, B. J.
10.1101/2024.02.13.580202 — neuroscience — Posted on 2024-02-14
2555 Plasticity of the Arabidopsis leaf lipidome and proteome in response to pathogen infection and heat stress
Scholz, P.; Doner, N.; Gutbrod, K.; Herrfurth, C.; Niemeyer, P. W.; Lim, M. S. S.; Blersch, K. F.; Schmitt, K.; Valerius, O.; Shanklin, J.; Feussner, I.; Doermann, P.; Braus, G.; Mullen, R. T.; Ischebeck, T.
10.1101/2024.02.09.579702 — plant biology — Posted on 2024-02-14
2556 Microenvironment Shapes Cell State, Plasticity, and Heterogeneity of Small Cell Lung Cancer
Desai, P. A.; Takahashi, N.; Kumar, R.; Nichols, S.; Malin, J.; Hunt, A.; Schultz, C.; Cao, Y.; Tillo, D.; Nousome, D.; Chauhan, L.; Sciuto, L.; Jordan, K.; Rajapakse, V.; Lissa, D.; Zhang, Y.; Kumar, S.; Pongor, L.; Singh, A.; Schroeder, B.; Sharma, A.; Chang, T.; Vilimas, R.; Pinkiert, D.; Graham, C.; Butcher, D.; Warmer, A.; Sebastian, R.; Mahon, M.; Baker, K.; Cheng, J.; Berger, A.; Lake, R.; Abel, M.; Krishnamurthy, M.; Chrisaffis, G.; Upadhyay, D.; Fitzgerald, P.; Nirula, M.; Goyal, S.; Atkinson, D.; Bateman, N. W.; Abulez, T.; Nair, G.; Apolo, A.; Guha, U.; Baktiar, K.; El Meskini, R.;
10.1101/2024.02.09.579028 — cancer biology — Posted on 2024-02-14
2559 Urinary Metabolomic Profile is Minimally Impacted by Common Storage Conditions and Additives
Weldon, K. C.; Panitchpakdi, M.; Caraballo-Rodriguez, A. M.; Wolfe, A. J.; Dorrestein, P. C.; Brubaker, L.; Burnett, L.
10.1101/2024.02.12.579937 — molecular biology — Posted on 2024-02-14
2560 Bifidobacterium longum subsp. longum BG-L47 boosts growth and activity of Limosilactobacillus reuteri DSM 17938 and its extracellular membrane vesicles
Ermann Lundberg, L.; Pallabi Mishra, P.; Liu, P.; Forsberg, M. M.; Sverremark-Ekström, E.; Grompone, G.; Hakansson, S.; Linninge, C.; Roos, S.
10.1101/2024.02.12.579962 — microbiology — Posted on 2024-02-14
2561 Time-varying Spatial Propagation of Brain Networks in fMRI data
Bostami, B.; Lewis, N.; Agcaoglu, O.; Turner, J. A.; van Erp, T. G. M.; Ford, J. M.; Calhoun, V.; Iraji, A.
10.1101/2024.02.12.579169 — neuroscience — Posted on 2024-02-14
2562 Cross-species real time detection of trends in pupil size fluctuation
Kronemer, S. I.; Gobo, V. E.; Teves, J. B.; Burk, D. C.; Shahsavarani, S.; Walsh, C. R.; Gonzalez-Castillo, J.; Bandettini, P. A.
10.1101/2024.02.12.579393 — neuroscience — Posted on 2024-02-14
2563 Natural Variation in Age-Related Dopamine Neuron Degeneration is Glutathione-Dependent and Linked to Life Span
Coleman, C. R.; Pallos, J.; Arreola-Bustos, A.; Wang, L.; Raftery, D.; Promislow, D. E. L.; Martin, I.
10.1101/2024.02.12.580013 — neuroscience — Posted on 2024-02-14
2568 Proteostasis as a fundamental principle of Tau immunotherapy
Cruz, E.; Nisbet, R. M.; Padmanabhan, P.; van Waardenberg, A.; Graham, M. E.; Nkajja, G.; Tapaswi, S.; Robinson, P.; Gotz, J.
10.1101/2024.02.12.580007 — neuroscience — Posted on 2024-02-14
2569 Identification of hippocampal area CA2 in hamster and vole brain
Siegler, P. N.; Shaughnessy, E. K.; Horman, B.; Vierling, T. T.; King, D. H.; Patisaul, H. B.; Huhman, K. L.; Alexander, G. M.; Dudek, S. M.
10.1101/2024.02.12.579957 — neuroscience — Posted on 2024-02-14
2576 The spatial representation of temperature in the thalamus
Leva, T.; Whitmire, C.; Sauve, I.; Bokiniec, P.; Memler, C.; Horn, B.; Vestergaard, M.; Carta, M.; Poulet, J. F. A.
10.1101/2024.02.13.580167 — neuroscience — Posted on 2024-02-14
2578 DYRKP kinase regulates cell wall degradation in Chlamydomonas by inducing matrix metalloproteinase expression
Kim, M.; Jorge, G. L.; Aschern, M.; Cuine, S.; Huleux, M.; Mekhalfi, M.; Yang, J.-S.; Thelen, J. J.; Beisson, F.; Peltier, G.; Li-Beisson, Y.
10.1101/2024.02.09.579704 — plant biology — Posted on 2024-02-14
2579 Scalable and efficient DNA sequencing analysis on different compute infrastructures aiding variant discovery
Hanssen, F.; Garcia, M. U.; Folkersen, L.; Pedersen, A. S.; Lescai, F.; Jodoin, S.; Miller, E.; Seybold, M.; Wacker, O.; Smith, N.; nf-core community, ; Gabernet, G.; Nahnsen, S.
10.1101/2023.07.19.549462 — bioinformatics — Posted on 2024-02-14
2580 A Bayesian analysis of birth pulse effects on the probability of detecting Ebola virus in fruit bats
Pleydell, D. R. J.; Ndong Bass, I.; Mba Djondzo, F. A.; Meta Djomsi, D.; Kouanfack, C.; Peeters, M.; Cappelle, J.
10.1101/2023.08.10.552777 — ecology — Posted on 2024-02-14
2581 The rules of sex and strain: deciphering the chemical language of inbred and wild mouse conspecific scents
Nagel, M.; Niestroj, M.; Bansal, R.; Fleck, D.; Lampert, A.; Stopkova, R.; Stopka, P.; Ben-Shaul, Y.; Spehr, M.
10.1101/2023.06.24.546367 — neuroscience — Posted on 2024-02-14
2583 Flowtigs: safety in flow decompositions for assembly graphs
Sena, F.; Ingervo, E.; Khan, S.; Prjibelski, A.; Schmidt, S.; Tomescu, A. I.
10.1101/2023.11.17.567499 — bioinformatics — Posted on 2024-02-14
2584 A haplotype-resolved reference genome of Quercus alba sheds light on the evolutionary history of oaks
Larson, D. A.; Staton, M. E.; Kapoor, B.; Faridi, N.; Zhebentyayeva, T.; Fan, S.; Stork, J.; Thomas, A.; Ahmed, A.; Stanton, E.; Houston, A.; Schlarbaum, S.; Hahn, M. W.; Carlson, J.; Abbott, A.; DeBolt, S.; Nelson, D.
10.1101/2024.02.13.579671 — genomics — Posted on 2024-02-14
2585 Instantaneous change in hyphal diameter in basidiomycete fungi
Mazheika, I. S.; Voronko, O. V.; Kolomiets, O. L.; Kamzolkina, O. V.
10.1101/2024.02.12.579893 — cell biology — Posted on 2024-02-14
2587 A cellular and spatial atlas of TP53-associated tissue remodeling in lung adenocarcinoma
Zhao, W.; Kepecs, B.; Mahadevan, N. R.; Segerstolpe, A.; Weirather, J. L.; Besson, N. R.; Giotti, B.; Soong, B. Y.; Li, C.; Vigneau, S.; Slyper, M.; Wakiro, I.; Jane-Valbuena, J.; Ashenberg, O.; Rotem, A.; Bueno, R.; Rozenblatt-Rosen, O.; Pfaff, K.; Rodig, S.; Hata, A. N.; Regev, A.; Johnson, B. E.; Tsankov, A. M.
10.1101/2023.06.28.546977 — cancer biology — Posted on 2024-02-14
2588 Simultaneous multicolor fluorescence imaging using duplication-based PSF splitting
Van den Eynde, R.; Hertel, F.; Abakumov, S.; Krajnik, B.; Hugelier, S.; Auer, A.; Hellmeier, J.; Schlichthaerle, T.; Grattan, R. M.; Lidke, D. S.; Jungmann, R.; Leutenegger, M.; Vandenberg, W.; Dedecker, P.
10.1101/2022.10.04.510770 — biophysics — Posted on 2024-02-14
2590 A targetable N-terminal motif orchestrates α-synuclein oligomer to fibril conversion
Santos, J.; Cuellar, J.; Pallares, I.; Byrd, E. J.; Lends, A.; Moro, F.; Abdul-Shukkoor, M. B.; Pujols, J.; Velasco-Carneros, L.; Sobott, F.; Otzen, D. E.; Calabrese, A. N.; Muga, A.; Pedersen, J. S.; Loquet, A.; Valpuesta, J. M.; Radford, S.; Ventura, S.
10.1101/2023.02.10.527650 — biophysics — Posted on 2024-02-14
2592 Androgens at the skin surface regulate S. aureus pathogenesis through the activation of agr quorum sensing
John, M. S.; Chinnappan, M.; Artami, M.; Bhattacharya, M.; Keogh, R.; Kavanaugh, J.; Sharma, T.; Horswill, A. R.; Harris-Tryon, T. A.
10.1101/2024.02.10.579753 — microbiology — Posted on 2024-02-14
2593 Merging Multi-OMICs with Proteome Integral Solubility Alteration Unveils Antibiotic Mode of Action
Maity, R.; Zhang, X.; Liberati, F. R.; Ainsa, J. A.; Cutruzzola, F.; Rinaldo, S.; Sancho, J.; Scribani, C.; Gaetani, M.
10.1101/2023.09.07.556692 — microbiology — Posted on 2024-02-14
2594 Combining systems and synthetic biology for in vivo enzymology
Castano-Cerezo, S.; Chamas, A.; Kulyk, H.; Treitz, C.; Bellvert, F.; Tholey, A.; Galeote, V.; Camarasa, C.; Heux, S.; Garcia-Alles, L. F.; Millard, P.; Truan, G.
10.1101/2024.02.02.578620 — systems biology — Posted on 2024-02-14
2595 Evolution of plant cell-type-specific cis-regulatory elements
Yan, H.; Mendieta, J. P.; Zhang, X.; Marand, A. P.; Liang, Y.; Luo, Z.; Minow, M. A. A.; Roule, T.; Wagner, D.; Tu, X.; Wang, Y.; Zhong, S.; Wessler, S. R.; Schmitz, R. J.
10.1101/2024.01.08.574753 — plant biology — Posted on 2024-02-14
2598 Image processing tools for petabyte-scale light sheet microscopy data
Ruan, X.; Mueller, M.; Liu, G.; Görlitz, F.; Fu, T.-M.; Milkie, D. E.; Lillvis, J. L.; Kuhn, A.; Herr, C. Y. A.; Hercule, W.; Nienhaus, M.; Killilea, A. N.; Betzig, E.; Upadhyayula, S.
10.1101/2023.12.31.573734 — bioinformatics — Posted on 2024-02-14
2600 Encapsulation of AAVs into protein vault nanoparticles as a novel solution to gene therapy's neutralizing antibody problem
Collins, L. T.; Beatty, W.; Moyo, B.; Alves-Bezerra, M.; Hurley, A.; Lou, Q.; Zhou, Z. H.; Lagor, W.; Bao, G.; Ponnazhagan, S.; McNally, R.; Rome, L.; Curiel, D.
10.1101/2023.11.29.569229 — bioengineering — Posted on 2024-02-14
2601 Reconstitution of cytolinker-mediated crosstalk between actin and vimentin
Isturiz Petitjean, I.; Tran, Q. D.; Goutou, A.; Kabir, Z.; Wiche, G.; Leduc, C.; Koenderink, G. H.
10.1101/2023.10.27.564417 — biochemistry — Posted on 2024-02-14
2602 X-Ray Structure and enzymatic study of a Bacterial NADPHoxidase highlight the activation mechanism of eukaryoticNOX
Petit-Hartlein, I.; Vermot, A.; Thepaut, M.; Humm, A.-S.; Dupeux, F.; Dupuy, J.; Chaptal, V.; Marquez, J. A.; Smith, S. M. E.; Fieschi, F.
10.1101/2023.10.16.562591 — biochemistry — Posted on 2024-02-14
2603 Cis-regulatory control of transcriptional timing and noise in response to estrogen
GInley-Hidinger, M.; Abewe, H.; Osborne, K.; Richey, A.; Kitchen, N.; Mortenson, K. L.; Wissink, E. M.; Lis, J.; Zhang, X.; Gertz, J.
10.1101/2023.03.14.532457 — genomics — Posted on 2024-02-14
2605 Body size shapes song in honeyeaters
Hay, E. M.; McGee, M. D.; White, C. R.; Chown, S. L.
10.1101/2023.06.20.545811 — evolutionary biology — Posted on 2024-02-14
2610 Endogenous tagging using split mNeonGreen in human iPSCs for live imaging studies
Husser, M. C.; Pham, N. P.; Law, C.; Araujo, F. R. B.; Martin, V. J. J.; Piekny, A.
10.1101/2023.06.28.546942 — cell biology — Posted on 2024-02-14
2611 Brainstem Dbh+ Neurons Control Chronic Allergen-Induced Airway Hyperreactivity
Su, Y.; Xu, J.; Zhu, Z.; Ji, C.; Xu, L.; Yu, H.; Nudell, V. S.; Dash, B.; Moya, E.; Ye, L.; Nimmerjahn, A.; Sun, X.
10.1101/2023.02.04.527145 — cell biology — Posted on 2024-02-14
2617 Multiomic ALS signatures highlight sex differences and molecular subclusters and identify the MAPK pathway as therapeutic target
Caldi Gomes, L.; Hänzelmann, S.; Hausmann, F.; Khatri, R.; Oller, S.; Parvaz, M.; Tzeplaeff, L.; Pasetto, L.; Gebelin, M.; Ebbing, M.; Holzapfel, C.; Fabrizio Columbro, S.; Scozzari, S.; Knöferle, J.; Cordts, I.; Demleitner, A. F.; Deschauer, M.; Dufke, C.; Sturm, M.; Zhou, Q.; Zelina, P.; Sudria-Lopez, E.; Haack, T. B.; Streb, S.; Kuzma-Kozakiewicz, M.; Edbauer, D.; Pasterkamp, R. J.; Laczko, E.; Rehrauer, H.; Schlapbach, R.; Carapito, C.; Bonetto, V.; Bonn, S.; Lingor, P.
10.1101/2023.08.14.553180 — neuroscience — Posted on 2024-02-14
2618 Conduction Velocity, G-ratio, and Extracellular Water as Microstructural Characteristics of Autism Spectrum Disorder
Newman, B. T.; Jacokes, Z.; Venkadesh, S. T.; Webb, S. J.; Kleinhans, N. M.; McPartland, J. C.; Druzgal, T. J.; Pelphrey, K. A.; Van Horn, J. D.; For the GENDAAR Research Consortium,
10.1101/2023.07.23.550166 — neuroscience — Posted on 2024-02-14
2619 Minimal impact of proprioceptive loss on implicit sensorimotor adaptation and perceived movement outcome
Tsay, J. S.; Chandy, A. M.; Chua, R.; Miall, R. C.; Cole, J.; Farne, A.; Ivry, R. B.; Sarlegna, F. R.
10.1101/2023.01.19.524726 — neuroscience — Posted on 2024-02-14
2621 Multiple brain activation patterns for the same task
Nakuci, J.; Yeon, J.; Haddara, N.; Kim, J.-H.; Kim, S.-P.; Rahnev, D.
10.1101/2023.04.08.536107 — neuroscience — Posted on 2024-02-14
2622 A population code for idiothetic representations in the hippocampal-septal circuit
Etter, G.; van der Veldt, S.; Mosser, C.-A.; Hasselmo, M. E.; Williams, S.
10.1101/2023.11.10.566641 — neuroscience — Posted on 2024-02-14
2626 PSAP-genomic-regions: a method leveraging population data to prioritize coding and non-coding variants in whole genome sequencing for rare disease diagnosis
Ogloblinsky, M.-S.; Bocher, O.; Aloui, C.; Leutenegger, A.-L.; Ozisik, O.; Baudot, A.; Tournier-Lasserve, E.; Castillo-Madeen, H.; Lewinsohn, D.; Conrad, D. F.; Genin, E.; Marenne, G.
10.1101/2024.02.13.580050 — genetics — Posted on 2024-02-13
2627 Tick-borne zoonotic flaviviruses and Borrelia infections in wildlife hosts: what have field studies contributed?
Poisson, A.; Boulinier, T.; Bournez, L.; Gonzalez, G.; Migne, C. V.; Moutailler, S.; Faivre, B.; Metras, R.
10.1101/2023.08.25.554822 — ecology — Posted on 2024-02-14
2629 Molecular signatures of cortical expansion in the human fetal brain
Ball, G.; Oldham, S.; Kyriakopoulou, V.; Williams, L. Z. J.; Karolis, V. R.; Price, A.; Hutter, J.; Seal, M. L.; Alexander-Bloch, A.; Hajnal, J. V.; Edwards, A. D.; Robinson, E. C.; Seidlitz, J.
10.1101/2024.02.13.580198 — neuroscience — Posted on 2024-02-13
2630 Enhancement of mediodorsal thalamus rescues aberrant belief dynamics in a mouse model with schizophrenia-associated mutation.
zhou, T.; Ho, Y.-Y.; Lee, R. X.; Fath, A. B.; He, K.; Scott, J.; Bajwa, N.; Hartley, N. D.; Wilde, J.; Gao, X.; Li, C.; Hong, E.; Nassar, M. R.; Wimmer, R. D.; Singh, T.; Halassa, M.; Feng, G.
10.1101/2024.01.08.574745 — neuroscience — Posted on 2024-02-14
2632 The RNA-binding activity of the TRIM-NHL protein NHL-2 is essential for miRNA-mediated gene regulation
Saadat, N.; Colson, R. N.; Grimme, A. L.; Seroussi, U.; Anderson, J. W. T.; Claycomb, J. M.; Wilce, M. C.; McJunkin, K.; Wilce, J. A.; Boag, P. R.
10.1101/2024.02.13.580109 — genetics — Posted on 2024-02-13
2633 NMR based metabolomic workflow to unravel the molecular mechanisms involved in strawberry vernalization
Fernandez-Veloso, A.; Hiniesta-Valero, J.; Guerra-Castellano, A.; Tomas, L.; De la Rosa, M. A.; Diaz-Moreno, I.
10.1101/2024.02.13.580094 — biochemistry — Posted on 2024-02-13
2635 Delaying cefiderocol resistance development in NDM-producing Enterobacter cloacae complex by combining cefiderocol with aztreonam in vitro.
Goepel, L.; Tran Thanh, T.; Tran Nguyen, M. T.; Hauswaldt, S.; Nur Canbulat, O.; Rupp, J.; Boutin, S.; Nurjadi, D.
10.1101/2024.02.13.579981 — microbiology — Posted on 2024-02-13
2637 iSCORE-PD: an isogenic stem cell collection to research Parkinson Disease
Busquets, O.; Li, H.; Syed, K. M.; Jerez, P. A.; Dunnack, J.; Bu, R. L.; Verma, Y.; Pangilinan, G. R.; Martin, A.; Straub, J.; Du, Y.; Simon, V. M.; Poser, S.; Bush, Z.; Diaz, J.; Sahagun, A.; Gao, J.; Hernandez, D.; Levine, K. S.; Booth, E. O.; Bateup, H.; Rio, D.; Hockemeyer, D.; Blauwendraat, C.; Soldner, F.
10.1101/2024.02.12.579917 — neuroscience — Posted on 2024-02-13
2638 Intrinsic diving reflex induces potent antioxidative response by activation of NRF2 signaling
Powell, K.; Wadolowski, S.; Tambo, W.; Strohl, J. J.; Kim, D.; Turpin, J.; al-Abed, Y.; Brines, M.; Huerta, P. T.; Li, C.
10.1101/2024.02.12.579910 — physiology — Posted on 2024-02-13
2640 Unveiling Tryptophan Dynamics and Functions Across Model Organisms via Quantitative Imaging
Wang, K.; Chen, T.; Zhang, X.; Cao, J.; Wang, P.; Wang, M.; Du, J.-l.; Mu, Y.; Tao, R.
10.1101/2024.02.12.580012 — biochemistry — Posted on 2024-02-13
2642 Do light eaters live shorter lives? The case of ultralight Caenorhabditis elegans
Zhang, X.; Gharibi, H.; Beusch, C. M.; Meng, Z.; Saei Dibavar, A.; Gaetani, M.; Zubarev, R.
10.1101/2024.02.13.580069 — biochemistry — Posted on 2024-02-13
2644 Spatial top-down proteomics for the functional characterization of human kidney
Zemaitis, K. J.; Fulcher, J. M.; Kumar, R.; Degnan, D. J.; Lewis, L. A.; Liao, Y.-C.; Velickovic, M.; Williams, S. M.; Moore, R. J.; Bramer, L. M.; Velickovic, D.; Zhu, Y.; Zhou, M.; Pasa-Tolic, L.
10.1101/2024.02.13.580062 — biochemistry — Posted on 2024-02-13
2645 High-throughput nano-flow proteomics using a dual-column electrospray source
Staes, A.; Boucher, K.; Dufour, S.; Maia, T. M.; Timmerman, E.; Van Haver, D.; Pauwels, J.; Demol, H.; Vandenbussche, J.; Impens, F.; Devos, S.
10.1101/2024.02.13.580084 — biochemistry — Posted on 2024-02-13
2646 Optical tweezers reveal that PfEBA and PfRH ligands, not PfMSP1, play a central role in Plasmodium-falciparum merozoite-erythrocyte attachment
Kals, E.; Kals, M.; Lees, R. A.; Introini, V.; Kemp, A.; Silvester, E.; Collins, C. R.; Umrekar, T.; Kotar, J.; Cicuta, P.; Rayner, J. C.
10.1101/2024.02.13.580055 — molecular biology — Posted on 2024-02-13
2647 The N-terminal helix of MarA as a key element in the mechanism of DNA binding
Corbella, M.; Moreira, C.; Bello-Madruga, R.; Torrent, M.; Kamerlin, S. C. L.; Blair, J. M. A.; Sancho-Vaello, E.
10.1101/2024.02.13.580091 — molecular biology — Posted on 2024-02-13
2649 AMPK-activator ATX-304 reduces oxidative stress and improves MASLD via metabolic switching
Holm, E.; Vermeulen, I.; Parween, S.; Lopez-Perez, A.; Cillero-Pastor, B.; Vandenbosch, M.; Remeseiro, S.; Hörnblad, A.
10.1101/2024.02.13.578901 — molecular biology — Posted on 2024-02-13
2650 LbCas12-mediated multiplex gene editing and 2-fluoroadenine counter-selection in Phytophthora palmivora
Verhoeven, T.; Pluis, M. H.; Peippo, M.; Couillaud, G.; van den Berg, G. C.; Evangelisti, E.
10.1101/2024.02.13.580060 — microbiology — Posted on 2024-02-13
2655 Biological management, rather than chemical management, promotes the interaction between plants and their microbiome
Zhao, T.; Jia, X.; Liu, X.; Nepal, J.; Attard, E.; Guyoneaud, R.; Treder, K.; Pawlowska, A.; Michalowska, D.; Berg, G.; Stocker, F.; Cernava, T.; Elzenga, J. T. M.; Salles, J. F.
10.1101/2024.02.12.579901 — microbiology — Posted on 2024-02-13
2657 Engineering multi-degrading bacterial communities to bioremediate soils contaminated with pesticides residues
Thieffry, S.; Aubert, J.; Devers-Lamrani, M.; Martin-Laurent, F.; Romdhane, S.; Rouard, N.; Siol, M.; Spor, A.
10.1101/2024.02.13.580075 — microbiology — Posted on 2024-02-13
2661 In-host evolution of classic to convergent Klebsiella pneumoniae sequence type 147 isolates and impact of associated capsular changes on different morphotypes
Sydow, K.; Dogan, E.; Schwabe, M.; Heiden, S. E.; Khan, M. M.; Müller, J. U.; Bohnert, J. A.; Baecker, D.; Schlüter, R.; Schierack, P.; Eger, E.; Idelevich, E. A.; Becker, K.; Schaufler, K.
10.1101/2024.02.13.580130 — microbiology — Posted on 2024-02-13
2663 SARS-CoV-2 Omicron lineage XBB spike structures, conformations, antigenicity, and receptor recognition
Zhang, Q. E.; Lindenberger, J.; Parsons, R.; Thakur, B.; Parks, R.; Park, C. S.; Huang, X.; Sammour, S.; Janowska, K.; Spence, T. N.; Edwards, R. J.; Martin, M.; Williams, W. B.; Gobeil, S.; Montefiori, D. C.; Korber, B.; Saunders, K. O.; Haynes, B. F.; Haynes, B. F.; Henderson, R.; Acharya, P.
10.1101/2024.02.12.580004 — biochemistry — Posted on 2024-02-13
2670 Accessible chromatin maps of inflammatory bowel disease intestine nominate cell-type mediators of genetic disease risk
Wayman, J. A.; Yang, Z.; Angerman, E.; Bonkowski, E.; Jurickova, I.; Chen, X.; Bejjani, A. T.; Parks, L.; Parameswaran, S.; Miethke, A. G.; VanDussen, K. L.; Dhaliwal, J.; Weirauch, M. T.; Kottyan, L. C.; Denson, L. A.; Miraldi, E. R.
10.1101/2024.02.09.579678 — genomics — Posted on 2024-02-13
2672 Phages reconstitute NAD+ to counter bacterial immunity
Osterman, I.; Samra, H.; Rousset, F.; Loseva, E.; Itkin, M.; Malitsky, S.; Yirmiya, E.; Millman, A.; Sorek, R.
10.1101/2024.02.11.579819 — microbiology — Posted on 2024-02-13
2676 Locus coeruleus injury modulates ventral midbrain neuroinflammation during DSS-induced colitis
Boles, J. S.; Holt, J.; Cole, C. L.; Neighbarger, N. K.; Urs, N. M.; Uriarte Huarte, O.; Tansey, M. G.
10.1101/2024.02.12.580010 — neuroscience — Posted on 2024-02-13
2678 Mitochondrial bioenergetics stimulates autophagy for pathological tau clearance in tauopathy neurons
Jia, N.; Ganesan, D.; Guan, H.; Jeong, Y. Y.; Han, S.; Nissenbaum, M.; Kusnecov, A. W.; Cai, Q.
10.1101/2024.02.12.579959 — neuroscience — Posted on 2024-02-13
2683 EMinsight: a tool to capture cryoEM microscope configuration and experimental outcomes for analysis and deposition.
Hatton, D.; Cha, J.; Riggs, S.; Harrison, P. J.; Thiyagalingam, J.; Clare, D. K.; Morris, K. L.
10.1101/2024.02.12.579963 — biophysics — Posted on 2024-02-13
2684 Complementary Cytoskeletal Feedback Loops Control Signal Transduction Excitability and Cell Polarity
Kuhn, J. A.; Banerjee, P.; Haye, A.; Robinson, D. N.; Iglesias, P. A.; Devreotes, P. N.
10.1101/2024.02.13.580131 — cell biology — Posted on 2024-02-13
2686 Discovery of SARS-CoV-2 papain-like protease (PLpro) inhibitors with efficacy in a murine infection model
Garnsey, M. R.; Robinson, M. C.; Nguyen, L. T.; Cardin, R.; Tillotson, J.; Mashalidis, E.; Aijia, Y.; Aschenbrenner, L.; Balesano, A.; Behzadi, A.; Boras, B.; Chang, J. S.; Eng, H.; Ephron, A.; Foley, T.; Ford, K.; Frick, J. M.; Gibson, S.; Li, H.; Hurst, B.; Kalgutkar, A. S.; Korczynska, M.; Lengyel-Zhand, Z.; Liping, G.; Meredith, H. R.; Patel, N. C.; Polivkova, J.; Rai, D.; Rose, C. R.; Rothan, H.; Sakata, S. K.; Vargo, T. R.; Qi, W.; Wu, H.; Liu, Y.; Yurgelonis, I.; Zhang, J.; Zhu, Y.; Zhang, L.; Lee, A. A.
10.1101/2024.01.26.577395 — microbiology — Posted on 2024-02-13
2687 Discovery of a novel inhibitor of macropinocytosis with antiviral activity
Porebski, B.; Christ, W.; Corman, A.; Haraldsson, M.; Barz, M.; Lidemalm, L.; Haggblad, M.; Illmain, J.; Wright, S.; Murga, M.; Schlegel, J.; Sezgin, E.; Bhabha, G.; Lauschke, V. M.; Lafarga, M.; Klingstrom, J.; Huhn, D.; Fernandez-Capetillo, O.
10.1101/2023.10.25.563967 — pharmacology and toxicology — Posted on 2024-02-13
2690 Divergent iron-regulatory states contribute to heterogeneity in breast cancer aggressiveness
Leineweber, W.; Rowell, M. Z.; Ranamukhaarachchi, S.; Walker, A. M.; Li, Y.; Villazon, J.; Farrera, A. M.; Hu, Z.; Yang, J.; Shi, L.; Fraley, S. I.
10.1101/2023.06.23.546216 — cancer biology — Posted on 2024-02-13
2691 Rapid growth and the evolution of complete metamorphosis in insects
Manthey, C.; Metcalf, J. C.; Monaghan, M. T.; Steiner, U. K.; Rolff, J.
10.1101/2024.02.12.579885 — evolutionary biology — Posted on 2024-02-13
2694 Short internal open reading frames regulate the translation of N-terminally truncated proteoforms
Fettig, R.; Gonda, Z.; Walter, N.; Sallmann, P.; Thanisch, C.; Winter, M.; Bauer, S.; Zhang, L.; Linden, G.; Litfin, M.; Etard, C.; Armant, O.; Vazquez, O.; Kassel, O.
10.1101/2023.11.09.566418 — molecular biology — Posted on 2024-02-13
2695 Evaluating HIV Infectivity and Virion Maturation Across Varied Producer Cells with a Novel FRET-Based Detection and Quantification Assay
McGraw, A.; Choi, J.; Narayan, K.; Gujar, S. S.; Arnette, C. N.; Tibebe, H.; Bose, L. M.; Hillmer, G.; Sullivan, C.; Izumi, T.
10.1101/2023.12.25.573317 — microbiology — Posted on 2024-02-13
2700 NeuroVelo: interpretable learning of cellular dynamics from single-cell transcriptomic data
Kouadri Boudjelthia, I.; Milite, S.; El Kazwini, N.; Fernandez-Mateos, J.; Valeri, N.; Huang, Y.; Sottoriva, A.; Sanguinetti, G.
10.1101/2023.11.17.567500 — bioinformatics — Posted on 2024-02-13
2707 Early life regulatory T cells modulate PPAR-gamma dependent skin pigmentation
Cho, I.; Xu, J. Z.; Aziz, H.; Lui, P. P.; Xie, B.; Tsai, P.-H.; Jeon, H.-Y.; Choi, J.; Ali, S.; Ali, N.
10.1101/2023.10.17.561843 — immunology — Posted on 2024-02-13
2708 Influence of chondroitin sulfate glycan sulfation patterns on histochemical labeling of perineuronal nets- a comparative study of interregional distribution in human and mouse brain
Belliveau, C.; Theberge, S.; Netto, S.; Rahimian, R.; Fakhfouri, G.; Hosdey, C.; Davoli, M. A.; Hendrickson, A.; Hao, K.; Giros, B.; Turecki, G.; Alonge, K. M.; Mechawar, N.
10.1101/2024.02.09.579711 — neuroscience — Posted on 2024-02-13
2709 Goal-directed motor actions drive acetylcholine dynamics in sensory cortex
Zou, J.; Willem de Gee, J.; Mridha, Z.; Trinh, S.; Erskine, A.; Jing, M.; Yao, J.; Walker, S.; Li, Y.; McGinley, M.; Hires, S. A.
10.1101/2021.12.21.473699 — neuroscience — Posted on 2024-02-13
2710 A neuronal least-action principle for real-time learning in cortical circuits
Senn, W.; Dold, D.; Kungl, A.; Ellenberger, B.; Jordan, J.; Bengio, Y.; Sacramento, J.; Petrovici, M. A.
10.1101/2023.03.25.534198 — neuroscience — Posted on 2024-02-13
2712 Psilocybin induces dose-dependent changes in functional network organization in rat cortex
Silverstein, B. H.; Kolbman, N.; Nelson, A.; Liu, T.; Guzzo, P.; Gilligan, J.; Lee, U.; Mashour, G. A.; Vanini, G.; Pal, D.
10.1101/2024.02.09.579718 — neuroscience — Posted on 2024-02-13
2713 Neurofeedback training can modulate task-relevant memory replay rate in rats
Gillespie, A. K.; Astudillo Maya, D. A.; Denovellis, E. L.; Desse, S.; Frank, L. M.
10.1101/2022.10.13.512183 — neuroscience — Posted on 2024-02-13
2717 Devaluation of response-produced safety signals reveals circuits for goal-directed versus habitual avoidance in dorsal striatum
Sears, R. M.; Andrade, E.; Samels, S. B.; Laughlin, L. C.; Moloney, D. M.; Wilson, D. A.; Alwood, M. R.; Moscarello, J. M.; Cain, C. K.
10.1101/2024.02.07.579321 — neuroscience — Posted on 2024-02-13
2718 Novel Mechanisms of Strigolactone-Induced DWARF14 Degradation in Arabidopsis thaliana
Sanchez Martin-Fontecha, E.; Cardinale, F.; Bürger, M.; Prandi, C.; Cubas, P.
10.1101/2024.01.10.574527 — plant biology — Posted on 2024-02-13
2722 Biochemical fractionation of human α-Synuclein in a Drosophila model of synucleinopathies
Imomnazarov, K.; Lopez-Scarim, J.; Bagheri, I.; Joers, V.; Tansey, M. G.; Martin-Pena, A.
10.1101/2024.02.05.579034 — biochemistry — Posted on 2024-02-13
2727 Plasmodium RON11 triggers biogenesis of the merozoite rhoptry pair and is essential for erythrocyte invasion
Anaguano, D.; Adewale Fasoro, O.; Vick, G. S.; Blauwkamp, J. A.; Yanik, S.; Fierro, M. A.; Absalon, S.; SRINIVASAN, P.; Muralidharan, V.
10.1101/2024.01.29.577654 — cell biology — Posted on 2024-02-13
2728 Megakaryocyte maturation involves activation of the adaptive unfolded protein response
Faiz, M.; Kalev-Zylinska, M. L.; Singleton, D. C.; Hay, M. P.; Ledgerwood, E. C.
10.1101/2023.07.26.550730 — cell biology — Posted on 2024-02-13
2729 Characterization of Pro-Fibrotic Signaling Pathways using Human Hepatic Organoids
Guan, Y.; Fang, Z.; Hu, A.; Roberts, S.; Wang, M.; Ren, W.; Johansson, P. K.; Heilshorn, S. C.; Enejder, A.; Peltz, G.
10.1101/2023.04.25.538102 — cell biology — Posted on 2024-02-13
2730 Metabolic imprints in the hydrogen isotopes of Archaeoglobus fulgidus tetraether lipids
Rhim, J. H.; Kopf, S.; McFarlin, J.; Maloney, A.; Batther, H.; Harris, C. M.; Zhou, A.; Feng, X.; Weber, Y.; Hoeft-McCann, S.; Pearson, A.; Leavitt, W. D.
10.1101/2023.11.29.569324 — microbiology — Posted on 2024-02-13
2732 Fluorescence hybridization chain reaction enables localization of multiple molecular classes combined with plant cell ultrastructure
Yu, Y.; Huss, D. J.; Li, M. J.; Wickramanayake, J. S.; Belanger, S.; Klebanovych, A.; Meyers, B. C.; Kellogg, E. A.; Czymmek, K. J.
10.1101/2024.01.29.577761 — plant biology — Posted on 2024-02-13
2734 A Compound that Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer
Uo, T.; Ojo, K. K.; Sprenger, C. C.; Epilepsia, K. S.; Perera, B. G. K.; Damodarasamy, M.; Sun, S.; Kim, S.; Hogan, H. H.; Hulverson, M. A.; Choi, R.; Whitman, G. R.; Barrett, L. K.; Michaels, S. A.; Xu, L. H.; Sun, V. L.; Arnold, S. L. M.; Pang, H. J.; Nguyen, M. M.; Vigil, A.-L. B. G.; Kamat, V.; Sullivan, L. B.; Sweet, I. R.; Vidadala, R.; Maly, D. J.; Van Voorhis, W. C.; Plymate, S. R.
10.1101/2023.07.01.547355 — cancer biology — Posted on 2024-02-13
2735 Mechanical coupling with the nuclear envelope shapes the S. pombe mitotic spindle
Begley, M. A.; Pagan Medina, C.; Couture, T.; Zareiesfandabadi, P.; Rapp, M. B.; Tirfe, M.; LeBlanc, S.; Betterton, M. D.; Elting, M. W.
10.1101/2022.12.28.522145 — biophysics — Posted on 2024-02-13
2737 Sequence-to-sequence translation from mass spectra to peptides with a transformer model
Yilmaz, M.; Fondrie, W. E.; Bittremieux, W.; Nelson, R.; Ananth, V.; Oh, S.; Noble, W. S.; Melendez, C.
10.1101/2023.01.03.522621 — bioinformatics — Posted on 2024-02-13
2741 Substrate recognition principles for the PP2A-B55 protein phosphatase
Kruse, T.; Garvanska, D.; Varga, J. K.; Garland, W.; McEwan, B.; Hein, J.; Weisser, M. B.; Puy, I. B.; Chan, C.; Parrila, P. S.; Lopez-Mendez, B.; Jeyaprakash, A. A.; Schueler-Furman, O.; Jensen, T. H.; Kettenbach, A.; Nilsson, J.
10.1101/2024.02.10.579793 — cell biology — Posted on 2024-02-13
2743 Female specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and Estrogen Receptor α
Molinaro, G.; Bowles, J. E.; Croom, K.; Gonzalez, D.; Mirjafary, S.; Birnbaum, S.; Razak, K. A.; Gibson, J. R.; Huber, K. M.
10.1101/2023.08.10.552857 — neuroscience — Posted on 2024-02-13
2744 Automated cell annotation in multi-cell images using an improved CRF_ID algorithm
Lee, H. J.; Liang, J.; Chaudhary, S.; Moon, S.; Yu, Z.; Wu, T.; Liu, H.; Choi, M.-K.; Zhang, Y.; Lu, H.
10.1101/2023.06.07.543949 — bioengineering — Posted on 2024-02-13
2749 Botulinum toxin intoxication requires retrograde transport and membrane translocation at the ER
Jeremy, Y. C.; Tay, F.; Bennion, R. E.; Loss, O.; Maignel, J.; Pons, L.; Foster, K.; Beard, M.; Bard, F. A.
10.1101/2023.10.17.562749 — cell biology — Posted on 2024-02-13
2750 40 Hz Steady-State Response in Human Auditory Cortex Is Shaped by GABAergic Neuronal Inhibition
Toso, A.; Wermuth, A. P.; Arazi, A.; Braun, A.; Grent-'t Jong, T.; Uhlhaas, P. J.; Donner, T. H.
10.1101/2023.10.20.563259 — neuroscience — Posted on 2024-02-13
2752 Semaphorin7A patterns neural circuitry in the lateral line of the zebrafish
Dasgupta, A.; Reagor, C. C.; Paik, S. P.; Snow, L. M.; Jacobo, A.; Hudspeth, A.
10.1101/2022.11.17.516962 — neuroscience — Posted on 2024-02-13
2753 Activating SRC/MAPK signaling via 5-HT1A receptor contributes to the effect of vilazodone on improving thrombocytopenia
Zhou, L.; Ni, C.; Liao, R.; Tang, X.; Yi, T.; Ran, M.; Huang, M.; Liao, R.; Zhou, X.; Qin, D.; Wang, L.; Huang, F.; Xie, X.; Wan, Y.; Luo, J.; Wang, Y.; Wu, J.
10.1101/2023.12.16.571981 — pharmacology and toxicology — Posted on 2024-02-13
2759 A nociceptive amygdala-striatal pathway for chronic pain aversion
Wojick, J. A.; Paranjapye, A.; Chiu, J. K.; Mahmood, M.; Oswell, C.; Kimmey, B. A.; Wooldridge, L. M.; McCall, N. M.; Han, A.; Ejoh, L. L.; Chehimi, S. N.; Crist, R. C.; Reiner, B. C.; Korb, E.; Corder, G.
10.1101/2024.02.12.579947 — neuroscience — Posted on 2024-02-13
2760 The ChAHP chromatin remodelling complex regulates neurodevelopmental disorder risk genes to scale the production of neocortical layers
Clemot-Dupont, S.; Fernandes, J. A. L.; Larrigan, S.; Sun, X.; Medisetti, S.; Stanley, R.; El Hankouri, Z.; Joshi, S. V.; Picketts, D. J.; Shekhar, K.; Mattar, P.
10.1101/2024.02.12.579820 — neuroscience — Posted on 2024-02-13
2762 Most axonal mitochondria in cortical pyramidal neuronslack mitochondrial DNA and consume ATP
Hirabayashi, Y.; Lewis, T. L.; Du, Y.; Virga, D. M.; Decker, A.; Coceano, G.; Alvelid, J.; Paul, M.; Hamilton, S.; Kneis, P.; Takahashi, Y.; Gaublomme, J.; Testa, I.; Polleux, F.
10.1101/2024.02.12.579972 — neuroscience — Posted on 2024-02-13
2765 Efficacy of Host Cell Serine Protease Inhibitor MM3122 against SARS-CoV-2 for Treatment and Prevention of COVID-19
Boon, A. C.; Bricker, T. L.; Fritch, E. J.; Leist, S. R.; Gully, K. L.; Baric, R. S.; Graham, R.; Troan, B. V.; Mahoney, M.; Janetka, J. W.
10.1101/2024.02.09.579701 — microbiology — Posted on 2024-02-12
2766 Phototropin connects blue light perception to starch metabolism in green algae
Yuan, Y.; Iannetta, A. A.; Kim, M.; Sadecki, P. W.; Arend, M.; Tsichla, A.; Ruiz-Sola, M. A.; Kepesidis, G.; Falconet, D.; Thevenon, E.; Tardif, M.; Brugiere, S.; Coute, Y.; Kleman, J.-P.; Sizova, I.; Schilling, M.; Jouhet, J.; Hegemann, P.; Li-Beisson, Y.; Nikoloski, Z.; Bastien, O.; Hicks, L. M.; Petroutsos, D.
10.1101/2024.02.12.579879 — plant biology — Posted on 2024-02-12
2767 KDM6A Regulates Immune Response Genes in Multiple Myeloma
Dupere-Richer, D.; Riva, A.; Maji, S.; Barwick, B. G.; Casella, H.; Sobh, A.; Quickstad, G.; Li, J.; de, u.; Piper, C.; Kulis, M.; Ezponda, T.; Martin-Subero, I.; Tonon, G.; Zhang, W.; Mitsiades, C.; Boise, L. H.; Bennett, R. L.; Licht, J. D.
10.1101/2024.02.12.579179 — cancer biology — Posted on 2024-02-12
2769 nanoFeatures: a cross-platform application to characterize nanoparticles from super-resolution microscopy images
Izquierdo-Lozano, C.; van Noort, N.; van Veen, S.; Tholen, M. M. E.; Grisoni, F.; Albertazzi, L.
10.1101/2024.02.12.579898 — bioinformatics — Posted on 2024-02-12
2771 Surface tension-driven sorting of human perilipins on lipid droplets
Araujo, A. R. D.; Bello, A. A.; Bigay, J.; Franckhauser, C.; Gautier, R.; Cazareth, J.; Kovacs, D.; Brau, F.; Fuggetta, N.; Copic, A.; Antonny, B.
10.1101/2024.02.12.579497 — biochemistry — Posted on 2024-02-12
2775 FABP4 as a Therapeutic Host Target Controlling SARS-CoV2 Infection
Baazim, H.; Koyuncu, E.; Tuncman, G.; Burak, M. F.; Merkel, L.; Bahour, N.; Karabulut, E.; Lee, G. Y.; Hanifehnezhad, A.; Karagoz, Z. F.; Foldes, K.; Engin, I.; Erman, A. G.; Oztop, S.; Filazi, N.; Gul, B.; Ceylan, A.; Cinar, O. O.; Can, F.; Kim, H.; Al-Hakeem, A.; Li, H.; Semerci, F.; Lin, X.; Yilmaz, E.; Ergonul, O.; Ozkul, A.; Hotamisligil, G. S.
10.1101/2024.02.10.579717 — microbiology — Posted on 2024-02-12
2779 Vitamin B12 variants structure soil microbial communities despite soil's vast reservoir of B12.
Hallberg, Z. F.; Nicolas, A. M.; Alvarez-Aponte, Z. I.; Mok, K. C.; Sieradzki, E. T.; Pett-Ridge, J.; Banfield, J.; Carlson, H. K.; Firestone, M. K.; Taga, M. E.
10.1101/2024.02.12.580003 — microbiology — Posted on 2024-02-12
2781 A new archaeal virus that suppresses the transcription of host immunity genes
Turgeman-Grott, I.; Golan, N.; Neri, U.; Naki, D.; Altman-Price, N.; Eizenshtein, K.; Choudhary, D. K.; Levy, R.; Papke, R. T.; Himani, H.; Reshef, L.; Gophna, U.
10.1101/2024.02.12.579488 — microbiology — Posted on 2024-02-12
2785 Intermolecular Energy Migration via HomoFRET Captures the Modulation in the Material Property of Phase-Separated Biomolecular Condensates
Joshi, A.; Walimbe, A.; Sarkar, S.; Arora, L.; Kaur, G.; Jhandai, P.; Chatterjee, D.; Banerjee, I.; Mukhopadhyay, S.
10.1101/2024.02.12.579899 — biophysics — Posted on 2024-02-12
2786 Low-dose cryo-electron ptychography of proteins at sub-nanometer resolution
Kucukoglu, B.; Mohammed, I.; Guerrero-Ferreira, R. C.; Ribet, S.; Varnavides, G.; Leidl, M. L.; Lau, K.; Nazarov, S.; Myasnikov, A.; Sachse, C.; Mueller-Caspary, K.; Ophus, C.; Stahlberg, H.
10.1101/2024.02.12.579607 — biophysics — Posted on 2024-02-12
2787 nQuack: An R package for predicting ploidal level from sequence data using site-based heterozygosity
Gaynor, M. L.; Landis, J. B.; O'Connor, T. K.; Laport, R. G.; Doyle, J. J.; Soltis, D. E.; Ponciano, J. M.; Soltis, P. S.
10.1101/2024.02.12.579894 — bioinformatics — Posted on 2024-02-12
2788 One to rule them all? Assessing the performance of Forest Europe's biodiversity indicators against multitaxonomic data
Paillet, Y.; Zapponi, L.; Schall, P.; Monnet, J.-M.; Ammer, C.; Balducci, L.; Boch, S.; Brazaitis, G.; Campanaro, A.; Chianucci, F.; Doerfler, I.; Fischer, M.; Gosselin, M.; Gossner, M. M.; Heilmann-Clausen, J.; Hofmeister, J.; Hosek, J.; Kepfer-Rojas, S.; Odor, P.; Tinya, F.; Trentanovi, G.; Vacchiano, G.; Vandekerkhove, K.; Weisser, W. W.; Burrascano, S.
10.1101/2024.02.12.579875 — ecology — Posted on 2024-02-12
2789 SpoIIDMP-driven peptidoglycan rearrangement is crucial for ribosome translocation into the spore.
Iwanska, O.; Latoch, P.; Kovalenko, M.; Lichocka, M.; Holowka, J.; Serwa, R.; Grzybowska, A.; Zakrzewska-Czerwinska, J.; Starosta, A. L.
10.1101/2024.02.12.579902 — microbiology — Posted on 2024-02-12
2790 Human color constancy in cast shadows
Morimoto, T.; Sato, M.; Sunaga, S.; Uchikawa, K.
10.1101/2024.02.10.579744 — neuroscience — Posted on 2024-02-12
2792 The BioRECIPE Knowledge Representation Format
Holtzapple, E.; Luo, H.; Tang, D.; Zhou, G.; Arazkhani, N.; Hansen, C.; Telmer, C. A.; Miskov-Zivanov, N.
10.1101/2024.02.12.579694 — systems biology — Posted on 2024-02-12
2794 Direct, bisulfite-free 5mC and 5hmC sequencing at single-cell resolution
Chen, X.; Cheng, J.; Kong, L.; Shu, X.; Xu, H.; Inoue, M.; Berrocal, M. S. F.; Doskeland, D. S.; Sivakumar, S.; Liu, Y.; Ye, J.; Song, C.-X.
10.1101/2024.02.12.579864 — genomics — Posted on 2024-02-12
2795 Gene-edited primary muscle stem cells rescue dysferlin-deficient muscular dystrophy
Escobar Fernandez, H.; Di Francescantonio, S.; Marg, A.; Zhogov, A.; Krishna, S.; Metzler, E.; Petkova, M.; Daumke, O.; Kuehn, R.; Spuler, S.
10.1101/2024.02.12.579813 — genetics — Posted on 2024-02-12
2796 Rapid growth and the evolution of complete metamorphosis in insects
Manthey, C.; Metcalf, J. C.; Monaghan, M. T.; Steiner, U. K.; Rolff, J.
10.1101/2024.02.12.579885 — evolutionary biology — Posted on 2024-02-12
2799 Instantaneous change in hyphal diameter in basidiomycete fungi
Mazheika, I. S.; Voronko, O. V.; Kolomiets, O. L.; Kamzolkina, O. V.
10.1101/2024.02.12.579893 — cell biology — Posted on 2024-02-12
2802 Reverse engineering placebo analgesia
Chen, B.; Goldstein, N.; Dziubek, J.; Zhao, S.; Harrahill, A.; Sundai, A.; Choi, S.; Prevosto, V.; Wang, F.
10.1101/2024.02.12.579946 — neuroscience — Posted on 2024-02-12
2803 Functional architecture of intracellular oscillations in hippocampal dendrites
Liao, Z.; Gonzalez, K. C.; Li, D.; Yang, C.; Holder, D.; McClain, N.; Zhang, G.; Evans, S.; Chavarha, M.; Yi, J.; Makinson, C.; Lin, M.; Losonczy, A.; Negrean, A.
10.1101/2024.02.12.579750 — neuroscience — Posted on 2024-02-12
2806 Psilocybin induces dose-dependent changes in functional network organization in rat cortex
Silverstein, B. H.; Kolbman, N.; Nelson, A.; Liu, T.; Guzzo, P.; Gilligan, J.; Lee, U.; Vanini, G.; Pal, D.
10.1101/2024.02.09.579718 — neuroscience — Posted on 2024-02-12
2808 Zapit: Open Source Random-Access Photostimulation For Neuroscience
Lohse, M.; Gauld, O. M.; Skretowska, M. T.; Vincent, P.; Pajot-Moric, Q.; Townsend, S.; Duan, C. A.; Akrami, A.; Mrsic-Flogel, T. D.; Campbell, R. A.
10.1101/2024.02.12.579892 — neuroscience — Posted on 2024-02-12
2809 A latent pool of neurons silenced by sensory-evoked inhibition can be recruited to enhance perception
Gauld, O. M.; Packer, A. M.; Russell, L. E.; Dalgleish, H. W. P.; Iuga, M.; Sacadura, F.; Roth, A.; Clark, B. A.; Hausser, M.
10.1101/2024.02.12.579847 — neuroscience — Posted on 2024-02-12
2811 The impact of face masks on face-to-face neural tracking of speech: auditory and visual obstacles
Fantoni, M.; Federici, A.; Camponogara, I.; Handjaras, G.; Martinelli, A.; Bednaya, E.; Ricciardi, E.; Pavani, F.; Bottari, D.
10.1101/2024.02.12.577414 — neuroscience — Posted on 2024-02-12
2815 Iguanas from above: Citizen scientists provide reliable counts of endangered Galapagos marine iguanas from drone imagery
Varela-Jaramillo, A.; Winkelmann, C.; Rivas-Torres, G.; Guayasamin, J. M.; Steinfartz, S.; MacLeod, A.
10.1101/2024.02.09.579637 — zoology — Posted on 2024-02-12
2816 Proteomic profiling of intracranial atherosclerotic plaque in the human brain
Hao, Q.; Wang, E.; Wang, J.; Wu, Z.; Crary, J. F.; Sharma, S.; Thorn, E. L.; Elahi, F.; Zhang, B.; Peng, J.
10.1101/2024.02.10.579787 — systems biology — Posted on 2024-02-12
2818 Selective enrichment of high-affinity clade II N2O-reducers in a mixed culture
Laureni, M.; Corbera Rubio, F.; Kim, D. D.; Browne, S.; Roothans, N.; Weissbrodt, D. G.; Olavarria, K. O.; de Jonge, N.; Yoon, S.; Pabst, M.; van Loosdrecht, M. C. M.
10.1101/2024.02.09.579283 — systems biology — Posted on 2024-02-12
2820 Two distinct mechanisms for Nav1.7 null analgesia
Kanellopoulos, A.; Tian, N.; Cox, J. J.; Zhao, J.; Woods, G.; Wood, J.
10.1101/2024.02.12.579826 — neuroscience — Posted on 2024-02-12
2821 Modeling Hereditary Diffuse Leukoencephalopathy with Axonal Spheroids using microglia-sufficient brain organoids
Wong, W. J.; Zhu, Y.; Wang, H.; Qian, J. W.; Li, Z.; Song, L.; Liu, Z.; Wei, G.; Zhang, S. Y.; Su, B.; Ping, H. F.; Wang, K.; Ginhoux, F.
10.1101/2024.02.12.579869 — neuroscience — Posted on 2024-02-12
2826 Intrauterine Growth-Restricted Pregnant Rats, from Hypertensive Placental Ischemic Dams Display Preeclamptic-like Symptoms: A New Rodent Model of Preeclampsia
Smith, J.; Powell, M.; Cromartie, W.; Smith, S.; Jones, K.; Castillo, A.; Shaw, J.; Editone, J.; Howard-Cunningham, A.; Tatum, R.; Smith, A. N.; Fisher, B.; Booz, G. W.; CUNNINGHAM, M. W.
10.1101/2024.02.07.579407 — physiology — Posted on 2024-02-12
2829 Synthesis and Biological Evaluation of Novel MB327 Analogs as Resensitizers for Desensitized Nicotinic Acetylcholine Receptors after Intoxication with Nerve Agents
Bernauer, T.; Nitsche, V.; Kaiser, J.; Gertzen, C. G. W.; Hoefner, G.; Niessen, K. V.; Seeger, T.; Steinritz, D.; Worek, F.; Gohlke, H.; Wanner, K. T.; Paintner, F. F.
10.1101/2024.02.09.579646 — pharmacology and toxicology — Posted on 2024-02-12
2837 Community density patterns estimated by species distribution modeling: the case study of an insect virus interaction
Dupas, S.; Zeddam, J.-L.; Orbe, K.; Barrera Cubillos, G. P.; Villamizar, L. F.; Mora, P.; Suquillo, J.; Dangles, O.; Lopez Avilla, A.; Cotes Prado, A. M.; Silvain, J.-F.
10.1101/2024.02.08.579470 — ecology — Posted on 2024-02-12
2839 Microtubule-dependent orchestration of centriole amplification in brain multiciliated cells
Boudjema, A.-R.; Balague, R.; Jewett, C. E.; LoMastro, G. M.; Mercy, O.; Al Jord, A.; Faucourt, M.; Schaeffer, A.; Nous, C.; Delgehyr, N.; Holland, A. J.; Spassky, N.; Meunier, A.
10.1101/2024.02.09.579615 — cell biology — Posted on 2024-02-12
2842 IL-17C plays a role in the pathophysiology of acute recurrent tonsillitis
Clapperton, M.; Kunanandam, T.; Florea, C. D.; Cunningham, M. R.; Douglas, C.; McConnell, G.
10.1101/2024.02.08.578879 — immunology — Posted on 2024-02-12
2846 Extracellular disposal of nuclear waste by APP: a protective mechanism impaired in Alzheimer's disease
Dougnon, G.; Otsuka, T.; Nakamura, Y.; Sakai, A.; Yamanaka, T.; Matsui, N.; Nakahara, A.; Ito, A.; Hatano, A.; Matsumoto, M.; Igarashi, H.; Kakita, A.; Ueno, M.; Matsui, H.
10.1101/2024.02.10.579739 — neuroscience — Posted on 2024-02-12
2847 Influence of insulin sensitivity on food cue evoked functional brain connectivity in children
Semeia, L.; Veit, R.; Zhao, S.; Luo, S.; Angelo, B.; Birkenfeld, A. L.; Preissl, H.; Xiang, A. H.; Kullmann, S.; Page, K. A.
10.1101/2024.02.12.579924 — neuroscience — Posted on 2024-02-12
2848 Dorsal Raphe to Basolateral Amygdala Corticotropin-Releasing Factor Circuit Regulates Cocaine-Memory Reconsolidation
Ritchie, J. L.; Qi, S.; Soto, D. A.; Swatzell, S. E.; Grenz, H. I.; Pruitt, A. Y.; Artimenia, L. M.; Cooke, S. K.; Berridge, C. W.; Fuchs, R. A.
10.1101/2024.02.10.579725 — neuroscience — Posted on 2024-02-12
2849 Investigating EMT-mediated resistance to EGFR tyrosine kinase inhibitors in NSCLC using innovative organoid models
Kobayashi, N.; Katakura, S.; Fukuda, N.; Teranishi, S.; Kubo, S.; Kamimaki, C.; Matsumoto, H.; Somekawa, K.; Kaneko, A.; Ishikawa, Y.; Okudela, K.; Sekine, K.; Kaneko, T.
10.1101/2024.02.08.579426 — cancer biology — Posted on 2024-02-12
2850 Identification of leukemia stem cell subsets with distinct transcriptional, epigenetic and functional properties
Boutzen, H.; Murison, A.; Wang, J. C. Y.; Arlidge, C.; Lupien, M.; Kaufmann, K. B.; Dick, J. E.
10.1101/2024.02.09.579319 — cancer biology — Posted on 2024-02-12
2852 Cell-autonomous GP130 activation suppresses prostate cancer development via STAT3/ARF/p53-driven senescence and confers an immune-active tumor microenvironment
Sternberg, C.; Limberger, T.; Raigel, M.; Trachtova, K.; Schlederer, M.; Lindner, D.; Kodajova, P.; Yang, J.; Ziegler, R.; Neubauer, H. A.; Dey, S.; Redmer, T.; Stoiber, S.; Hejret, V.; Tichy, B.; Tomberger, M.; Harbusch, N. S.; Tangermann, S.; Oberhuber, M.; Bystry, V.; Persson, J. L.; Pospisilova, S.; Wolf, P.; Sternberg, F.; Hoegler, S.; Lagger, S.; Rose-John, S.; Kenner, L.
10.1101/2024.02.11.579838 — cancer biology — Posted on 2024-02-12
2853 Influence of chondroitin sulfate glycan sulfation patterns on histochemical labeling of perineuronal nets- a comparative study of interregional distribution in human and mouse brain
Belliveau, C.; Theberge, S.; Netto, S.; Rahimian, R.; Fakhfouri, G.; Hosdey, C.; Davoli, M. A.; Hendrickson, A.; Hao, K.; GIROS, B.; Alonge, K. M.; Mechawar, N.
10.1101/2024.02.09.579711 — neuroscience — Posted on 2024-02-12
2854 Coordinated Immune Cell Networks in the Bone Marrow Microenvironment Define the Graft versus Leukemia Response with Adoptive Cellular Therapy
Maurer, K.; Park, C.; Mani, S.; Borji, M.; Penter, L.; Jin, Y.; Zhang, J. Y.; Shin, C.; Brenner, J. R.; Southard, J.; Krishna, S.; Lu, W.; Lyu, H.; Abbondanza, D.; Mangum, C.; Olsen, L. R.; Neuberg, D. S.; Bachireddy, P.; Farhi, S. L.; Li, S.; Livak, K. J.; Ritz, J.; Soiffer, R. J.; Wu, C. J.; Azizi, E.
10.1101/2024.02.09.579677 — cancer biology — Posted on 2024-02-12
2857 Cyclin-dependent kinase 5 (Cdk5) activity is modulated by light and gates rapid phase shifts of the circadian clock
Brenna, A.; Borsa, M.; Saro, G.; Ripperger, J. A.; Glauser, D. A.; Yang, Z.; Adamantidis, A.; Albrecht, U.
10.1101/2024.02.08.579499 — neuroscience — Posted on 2024-02-12
2858 Medulloblastoma oncogene aberrations are not involved in tumor initiation, but essential for disease progression and therapy resistance
Okonechnikov, K.; Joshi, P.; Koerber, V.; Rademacher, A.; Bortolomeazzi, M.; Mallm, J.-P.; da Silva, P. B. G.; Statz, B.; Sepp, M.; Sarropoulos, I.; Yamada-Saito, T.; Vaillant, J.; Wittmann, A.; Schramm, K.; Blattner-Johnson, M.; Fiesel, P.; Jones, B.; Milde, T.; Pajtler, K.; van Tilburg, C. M.; Witt, O.; Bochennek, K.; Weber, K. J.; Nonnenmacher, L.; Reimann, C.; Schueller, U.; Mynarek, M.; Rutkowski, S.; Jones, D. T. W.; Korshunov, A.; Rippe, K.; Westermann, F.; Thongjuea, S.; Hoefer, T.; Kaessmann, H.; Kutscher, L. M.; Pfister, S. M.
10.1101/2024.02.09.579690 — cancer biology — Posted on 2024-02-12
2859 Spatiotemporal regulation of the hepatocyte growth factor receptor MET activity by sorting nexins 1 and 2 in HCT116 colorectal cancer cells
Garcia Delgado, L.; Derome, A.; Longpre, S.; Giroux-Dansereau, M.; Basbous, G.; Lavoie, C. L.; Saucier, C.; Denault, J.-B.
10.1101/2024.02.10.579658 — cancer biology — Posted on 2024-02-12
2863 Biocompatible Neodymium-Doped Nanocrystals as Probes for Diffraction-limited, in vitro Temperature Sensing
Bravo, M.; Yang, S.; Brooke, S.; Wen, D.; Taemaitree, F.; Zaman, S.; Uji-i, H.; Rocha, S.; Mulvaney, P.; Hutchison, J. A.
10.1101/2024.02.08.579538 — biophysics — Posted on 2024-02-12
2864 Nanoscale interaction of endonuclease APE-1 with DNA characterized by atomic force microscopy
Vemulapalli, S.; Hashemi, M.; Chen, Y.; Pramanik, S.; Bhakat, K. K.; Lyubchenko, Y. L.
10.1101/2024.02.11.579811 — biophysics — Posted on 2024-02-12
2865 Biochemical, biophysical, and structural investigations of two mutants (C154Y and R312H) of the human Kir2.1 channel involved in the Andersen-Tawil syndrome.
Zuniga, D.; Zoumpoulakis, A.; Veloso, R. F.; Peverini, L.; Shi, S.; Pozza, A.; Kugler, V.; Bonnete, F.; Bouceba, T.; Wagner, R.; Corringer, P.-J.; Fernandes, C. A.; Venien-Bryan, C.
10.1101/2024.02.09.579451 — biophysics — Posted on 2024-02-12
2866 Determination of Absolute Intramolecular Distances in Proteins by Anomalous X-ray Scattering Interferometry
Stubhan, S.; Baptist, A. V.; Korosy, C.; Narducci, A.; Moya Munoz, G. G.; Wendler, N.; Lak, A.; Sztucki, M.; Cordes, T.; Lipfert, J.
10.1101/2024.02.09.579681 — biophysics — Posted on 2024-02-12
2867 Myosin-I Synergizes with Arp2/3 Complex to Enhance Pushing Forces of Branched Actin Networks
Xu, M.; Rutkowski, D. M.; Rebowski, G.; Boczkowska, M.; Pollard, L. W.; Dominguez, R.; Vavylonis, D.; Ostap, E. M.
10.1101/2024.02.09.579714 — biophysics — Posted on 2024-02-12
2868 A proteome-wide quantitative guide for nanoscale spatially resolved extraction of membrane proteins into native nanodiscs
Brown, C.; Ghosh, S.; McAllister, R.; Kumar, M.; Walker, G.; Sun, E.; Aman, T.; Panda, A.; Kumar, S.; Li, W. V.; Coleman, J.; Liu, Y.; Rothman, J. E.; Bhattacharyya, M.; Gupta, K.
10.1101/2024.02.10.579775 — biophysics — Posted on 2024-02-12
2869 Surface adhesion and membrane fluctuations influence the elastic modulus of extracellular vesicles
Stridfeldt, F.; Kylhammar, H.; Metem, P.; Pandey, V.; Agrawal, V.; Gorgens, A.; Mamand, D. R.; Gustafsson, O.; El Andaloussi, S.; Mitra, D.; Dev, A.
10.1101/2024.02.07.578591 — biophysics — Posted on 2024-02-12
2870 Generative artificial intelligence performs rudimentary structural biology modelling
Ille, A. M.; Markosian, C.; Burley, S. K.; Mathews, M. B.; Pasqualini, R.; Arap, W.
10.1101/2024.01.10.575113 — bioinformatics — Posted on 2024-02-12
2872 Cell circuits underlying nanomaterial specific respiratory toxicology
Voss, C.; Han, L.; Ansari, M.; Strunz, M.; Haefner, V.; Ballester-Lopez, C.; Angelidis, I.; Mayr, C. H.; Berthing, T.; Conlon, T.; Liu, Q.; Ren, H.; Zhou, Q.; Schmid, O.; Yildirim, A. O.; Rehberg, M.; Vogel, U.; Gothe-Schniering, J.; Theis, F. J.; Schiller, H. B.; Stoeger, T.
10.1101/2024.02.10.579746 — pharmacology and toxicology — Posted on 2024-02-12
2873 Classification of LTR Retrotransposons via Interaction Prediction
Cardoso, S. C. S.; Domingues, D. S.; Paschoal, A. R.; Fischer, C. N.; Cerri, R.
10.1101/2024.02.11.579858 — bioinformatics — Posted on 2024-02-12
2878 Scalable nonparametric clustering with unified marker gene selection for single-cell RNA-seq data
Nwizu, C.; Hughes, M.; Ramseier, M. L.; Navia, A.; Shalek, A. K.; Fusi, N.; Raghavan, S.; Winter, P. S.; Amini, A. P.; Crawford, L.
10.1101/2024.02.11.579839 — bioinformatics — Posted on 2024-02-12
2886 Thermostability and binding properties of single-chained Fv fragments derived from therapeutic antibodies
Tadokoro, T.; Tsuboi, H.; Nakamura, K.; Hayakawa, T.; Ohmura, R.; Kato, I.; Inoue, M.; Tsunoda, S.-i.; Niizuma, S.; Okada, Y.; Otsuguro, S.; Maenaka, K.
10.1101/2024.02.09.577534 — bioengineering — Posted on 2024-02-12
2887 HiCrayon reveals distinct layers of multi-state 3D chromatin organization
Nolan, B.; Harris, H. L.; Kalluchi, A.; Reznicek, T. E.; Cummings, C. T.; Rowley, M. J.
10.1101/2024.02.11.579821 — genomics — Posted on 2024-02-12
2890 Whole-Genome Sequencing of Three Extremophile Bacillus subtilis StrainsIsolated from the Atacama Desert
Cavanaugh, N. T.; Kumar, G.; Couto Frignani, M.; Thewedros, N.; Twahirwa, M.; Riquelme, C.; Hudson, A.; Chai, Y.; Godoy, V.
10.1101/2024.02.11.578748 — genomics — Posted on 2024-02-12
2895 Insights from Genetic Studies: SNP Analyses Confirm White Clover Naturalization in Brazil
de Alencar, A. S.; Suyama, Y.; Takahashi, D.; Mansano, V. d. F.; Lira, C. d. F.
10.1101/2024.02.09.579627 — genetics — Posted on 2024-02-12
2896 The ivory lncRNA regulates seasonal color patterns in buckeye butterflies
Fandino, R. A.; Brady, N. K.; Chatterjee, M.; McDonald, J. M. C.; Livraghi, L.; van der burg, K.; Mazo-Vargas, A.; Reed, R. D.
10.1101/2024.02.09.579733 — genetics — Posted on 2024-02-12
2897 Cytotoxicity and resistance evolution of a novel antifungal carbon nanoparticle
Poudel Sharma, S.; Paudyal, S.; Domena, J.; Zhou, Y.; Cleven, E. C.; Agatemor, C.; Van Dyken, J. D.; Leblanc, R. M.
10.1101/2024.02.11.579833 — evolutionary biology — Posted on 2024-02-12
2898 A long non-coding RNA at the cortex locus controls adaptive colouration in butterflies
Livraghi, L.; Hanly, J. J.; Evans, E.; Wright, C. J.; Loh, L. S.; Mazo-Vargas, A.; Kamrava, K.; Carter, A. T.; van der Heijden, E. S.; Reed, R. D.; Papa, R.; Jiggins, C. D.; Martin, A.
10.1101/2024.02.09.579710 — evolutionary biology — Posted on 2024-02-12
2904 Developmental pathways underlying sexual differentiation in a U/V sex chromosome system
Liesner, D.; Cossard, G.; Zheng, M.; Godfroy, O.; Barrera-Redondo, J.; Haas, F. B.; Coelho, S. M.
10.1101/2024.02.09.579736 — developmental biology — Posted on 2024-02-12
2905 Microtubule forces drive nuclear damage in LMNA cardiomyopathy
Amiad Pavlov, D.; Corredera, C. S.; Dehghany, M.; Heffler, J.; Shen, K. M.; Zuela - Sopilniak, N.; Randell, R.; Uchida, K.; Jain, R.; Shenoy, V.; Lammerding, J.; Prosser, B. L.
10.1101/2024.02.10.579774 — cell biology — Posted on 2024-02-12
2906 MDM2 acts as a timer reporting the length of mitosis
Fulcher, L.; Sobajima, T.; Gibbs-Seymour, I.; Barr, F. A.
10.1101/2023.05.26.542398 — cell biology — Posted on 2024-02-12
2909 TL1A/DR3 signaling regulates the generation of pathogenic Th9 cells in experimental inflammatory bowel disease
Menghini, P.; Butto, L.; Gomez-Nguyen, A.; Aladyshkina, N.; Buela, K.-A.; Osme, A.; Chan, R.; Bamias, G.; Pizarro, T. T.; Cominelli, F.
10.1101/2024.02.09.579684 — immunology — Posted on 2024-02-12
2910 Benchmark of cellular deconvolution methods using a multi-assay reference dataset from postmortem human prefrontal cortex
Huuki-Myers, L. A.; Montgomery, K. D.; Kwon, S. H.; Cinquemani, S.; Maden, S. K.; Eagles, N. J.; Kleinman, J. E.; Hyde, T. M.; Hicks, S. C.; Maynard, K. R.; Collado-Torres, L.
10.1101/2024.02.09.579665 — neuroscience — Posted on 2024-02-12
2911 Alterations in Lysosomal, Glial and Neurodegenerative Biomarkers in Patients with Sporadic and Genetic Forms of Frontotemporal Dementia
Hsiao-Nakamoto, J.; Chiu, C.-L.; VandeVrede, L.; Ravi, R.; Vandenberg, B.; De Groot, J.; Tsogtbaatar, B.; Fang, M.; Auger, P.; Gould, N. S.; Marchioni, F.; Powers, C. A.; Davis, S. S.; Suh, J. H.; Alkabsh, J.; Heuer, H. W.; Lago, A. L.; Scearce-Levie, K.; Seeley, W. W.; Boeve, B. F.; Rosen, H. J.; Berger, A.; Tsai, R.; Di Paolo, G.; Boxer, A. L.; Bhalla, A.; Huang, F.
10.1101/2024.02.09.579529 — neuroscience — Posted on 2024-02-12
2915 Closed-loop electrical stimulation to prevent focal epilepsy progression and long-term memory impairment
Ferrero, J. J.; Hassan, A. R.; Yu, Z.; Zhao, Z.; Ma, L.; Wu, C.; Shao, S.; Kawano, T.; Engel, J.; Doyle, W.; Devinsky, O.; Khodagholy, D.; Gelinas, J. N.
10.1101/2024.02.09.579660 — neuroscience — Posted on 2024-02-12
2917 Computational hemodynamic indices to identify Transcatheter Aortic Valve Implantation degeneration
Crugnola, L.; Vergara, C.; Fusini, L.; Fumagalli, I.; Luraghi, G.; Redaelli, A.; Pontone, G.
10.1101/2024.02.09.579647 — bioengineering — Posted on 2024-02-12
2921 Related PP2C phosphatases Pic3 and Pic12 negatively regulate immunity in tomato to Pseudomonas syringae
Xia, F.; Zhang, N.; Smith, R. E.; Chakraborty, J.; Sobol, G.; Tang, X.; Fei, Z.; Sessa, G.; Martin, G. B.
10.1101/2024.02.08.579555 — plant biology — Posted on 2024-02-12
2923 Carbon nanoparticle exposure strengthens water-relation parameters by stimulating abscisic acid pathway and aquaporins genes in rice
Kumar, A.; Manasa S, L.; Kashyap, J.; Mandal, S.; Mishra, G.; Rath, J.; Rout, G. R.; Panigrahi, K. C.; Panigrahy, M.
10.1101/2024.02.11.579789 — plant biology — Posted on 2024-02-12
2924 Whole-Plant Physiological Identification and Quantification of Disease Progression
Friedman, S.; Dalal, A.; Batat, D.; Burdman, S.; Sela, Y.; Hipsch, M.; Rosenwaser, S.; Marcos Hadad, E.; Covo, S.; Moshelion, M.
10.1101/2024.02.11.579801 — plant biology — Posted on 2024-02-12
2925 MUC17 is an essential small intestinal glycocalyx component that is disrupted in Crohn's disease
Layunta, E.; Javerfelt, S.; van de Koolwijk, F. C.; Sivertsson, M.; Dolan, B.; Arike, L.; Thulin, S.; Vallance, B. A.; Pelaseyed, T.
10.1101/2024.02.08.578867 — physiology — Posted on 2024-02-12
2926 Augmented-reality-based exercise increases salivary oxytocin
Shima, T.; Iijima, J.; Sutoh, H.; Terashima, C.; Matsuura, Y.
10.1101/2024.02.08.579578 — physiology — Posted on 2024-02-12
2927 Impaired transitioning of the FXR ligand binding domain to an active state underlies a PFIC5 phenotype
Behrendt, A.; Stindt, J.; Pfister, E.-D.; Grau, K.; Brands, S.; Bastianelli, A.; Droege, C.; Stalke, A.; Bonus, M.; Sgodda, M.; Cantz, T.; Franke, S.; Baumann, U.; Keitel, V.; Gohlke, H.
10.1101/2024.02.08.579530 — physiology — Posted on 2024-02-12
2931 NRP1-expressing myeloid cells promote arteriogenesis in the ischemic limb
Cho, J. S.; Patel, A. S.; Fantin, A.; Ludwinski, F. E.; Pichette, C.; Rudnicki, M.; Denti, L.; Mondragon, A.; Saha, P.; Smith, A.; Ruhrberg, C.; Moderai, B.
10.1101/2024.02.11.579823 — pathology — Posted on 2024-02-12
2932 PuMA: PubMed Gene-Celltype-Relation Atlas
Bickmann, L.; Sandmann, S.; Walter, C.; Varghese, J.
10.1101/2024.02.09.579584 — bioinformatics — Posted on 2024-02-12
2934 Whole-Genome Sequencing of a Janthinobacterium sp. Isolated from the Patagonian Desert
Cavanaugh, N. T.; Kumar, G.; Reverdy Pearson, A.; Colbert, J.; Riquelme, C.; Hudson, A. O.; Chai, Y.; Godoy, V.
10.1101/2024.02.11.579814 — genomics — Posted on 2024-02-12
2936 BPTF cooperates with MYCN and MYC to link neuroblastoma cell cycle control to epigenetic cellular states
Felipe, I.; Martinez de Villarreal, J.; Patel, K.; Martinez-Torrecuadrada, J. L.; Grossmann, L. D.; Roncador, G.; Cubells, M.; Farrel, A.; Nathan, K.; Sabroso-Lasa, S.; Sancho-Trevino, L.; Torres, K.; Martinez, D.; Munoz-Peralta, J.; Garcia, F.; Pogoriler, J.; Moreno, L.; Maris, J.; Real, F. X.
10.1101/2024.02.11.579816 — genomics — Posted on 2024-02-12
2937 Genetic regulation of injury induced heterotopic ossification in adult zebrafish
Kaliya-Perumal, A.-K.; Celik, C.; Carney, T. J.; Harris, M. P.; Ingham, P. W.
10.1101/2024.02.09.579618 — genetics — Posted on 2024-02-12
2940 How to validate a Bayesian evolutionary model
Mendes, F. K.; Bouckaert, R.; Carvalho, L. M.; Drummond, A. J.
10.1101/2024.02.11.579856 — evolutionary biology — Posted on 2024-02-12
2941 Pushing the limits: expanding the temperature tolerance of a coral photosymbiont through differing selection regimes
Scharfenstein, H. J.; Peplow, L. M.; Alvarez-Roa, C.; Nitschke, M.; Buerger, P.; Chan, W. Y.; van Oppen, M. J. H.
10.1101/2024.02.11.579409 — evolutionary biology — Posted on 2024-02-12
2943 What unexplored means: Mapping undersampled regions in natural history collections
Chakrabarty, P.; Ball, L.; Bedoya, A.; Rodriguez Machado, S.; Paredes-Burneo, D.; Rutledge, S.; Boyd, D.; Vander Pluym, D.; Babb-Biernacki, S.; Chipps, A.; Ozturk, R.; Terzi, Y.
10.1101/2024.02.09.579602 — ecology — Posted on 2024-02-12
2949 NF-κB Signaling is Required for X-Chromosome Inactivation Maintenance Following T cell Activation
Forsyth, K. S.; Toothacre, N. E.; Jiwarjka, N.; Driscoll, A. M.; Shallberg, L. A.; Cunningham-Rundles, C.; Barmettler, S.; Farmer, J. R.; Verbsky, J.; Routes, J.; Beiting, D. P.; Romberg, N.; May, M. J.; Anguera, M.
10.1101/2024.02.08.579505 — immunology — Posted on 2024-02-12
2950 Regulation of IFNgamma production by ZFP36L2 in T cells is context-dependent
Zandhuis, N. D.; Guislain, A.; Popalzij, A.; Engels, S.; Popovic, B.; Turner, M.; Wolkers, M. C.
10.1101/2024.02.09.579641 — immunology — Posted on 2024-02-12
2952 Asymmetric representation of symmetric semantic information in the human brain
Wang, J.; Kawahata, K.; Blanc, A.; Maeda, N.; Nishimoto, S.; Nishida, S.
10.1101/2024.02.09.579613 — neuroscience — Posted on 2024-02-12
2953 Impaired drainage through capillary-venous networks contributes to age-related white matter loss
Stamenkovic, S.; Schmid, F.; Weitermann, N.; Takasaki, K. T.; Bonney, S. K.; Sosa, M. J.; Li, Y.; Bennett, H. C.; Kim, Y.; Waters, J.; Shih, A.
10.1101/2024.02.11.579849 — neuroscience — Posted on 2024-02-12
2955 Dose escalation pre-clinical trial of novel Dok7-AAV in mouse model of DOK7 congenital myasthenia
Cossins, J. A.; Kozma, I.; Canzonetta, C.; Hawkins, A.; Beeson, D.; Sepulveda, P.; Dong, Y.
10.1101/2024.02.09.579626 — neuroscience — Posted on 2024-02-12
2958 Expression of Most Retrotransposons in Human Blood Correlates with Biological Aging
Tsai, Y.-T.; Seymen, N.; Thompson, I. R.; Zou, X.; Mumtaz, W.; Gerlevik, S.; Mufti, G. J.; Karimi, M. M.
10.1101/2024.02.09.579582 — genomics — Posted on 2024-02-12
2959 Polygenic architecture of adaptation to a high-altitude environment for Drosophila melanogaster wing shape and size.
Pelletier, K.; Bilodeau, M.; Pellizzari-Delano, I.; Siemon, M. D.; Huang, Y.; Pool, J. E.; Dworkin, I. E.
10.1101/2024.02.08.579525 — evolutionary biology — Posted on 2024-02-12
2961 UXS1 regulates UDP-GlcA levels to support growth of UGDH-high cancer cells
Wang, Y.; Zhou, C.; Bou-Tayeh, B.; Lisle, R.; Kriaucionis, S.; Shi, Y.
10.1101/2024.02.08.579288 — cell biology — Posted on 2024-02-12
2963 A Single-shot ChAd3 Vaccine Provides Protection from Intramuscular and Aerosol Sudan Virus Exposure
Honko, A. N.; Hunegnaw, R.; Moliva, J. I.; Ploquin, A.; Dulan, C. N. M.; Murray, T.; Carr, D.; Foulds, K. E.; Geisbert, J. B.; Geisbert, T. W.; Johnson, J. C.; Wollen-Roberts, S. E.; Trefry, J. C.; Stanley, D. A.; Sullivan, N. J.
10.1101/2024.02.07.579118 — immunology — Posted on 2024-02-12
2966 Impaired islet function with normal exocrine enzyme secretion is consistent across the head, body, and tail pancreas regions in type 1 diabetes
Drotar, D.; Mojica-Avila, A. K.; Bloss, D. T.; Cohrs, C. M.; Manson, C. T.; Posgai, A. L.; Williams, M. D.; Brusko, M. A.; Phelps, E. A.; Wasserfall, C. H.; Speier, S.; Atkinson, M. A.
10.1101/2024.02.08.579175 — pathology — Posted on 2024-02-12
2969 A Composite Biomarker Signature of Type 1 Diabetes Risk Identified via Augmentation of Parallel Multi-Omics Data from a Small Cohort
Alcazar, O.; Chuang, S.-T.; Ren, G.; Ogihara, M.; Webb-Robertson, B.-J. M.; Nakayasu, E. S.; Buchwald, P.; Abdulreda, M. H.
10.1101/2024.02.09.579673 — biochemistry — Posted on 2024-02-12
2970 Induction and in silico staging of human gastruloids with neural tube, segmented somites & advanced cell types
Hamazaki, N.; Yang, W.; Kubo, C.; Qiu, C.; Martin, B. K.; Garge, R. K.; Regalado, S. G.; Nichols, E.; Lee, C.; Daza, R. M.; Srivatsan, S.; Shendure, J.
10.1101/2024.02.10.579769 — developmental biology — Posted on 2024-02-12
2972 Transcriptomic landscape of human induced pluripotent stem cell-derived osteogenic differentiation identifies a regulatory role of KLF16
Ru, Y.; Ma, M.; Zhou, X.; Kriti, D.; Cohen, N.; Souza, S.; Schaniel, C.; Motch Perrine, S. M.; Kuo, S.; Pinto, D.; Housman, G.; Wu, M.; Holmes, G.; Schadt, E.; van Bakel, H.; Zhang, B.; Jabs, E. W.
10.1101/2024.02.11.579844 — molecular biology — Posted on 2024-02-12
2973 PINK1 is a target of T cell responses in Parkinson's disease
Williams, G. P.; Michaelis, T.; Rodrigues Lima-Junior, J.; Frazier, A.; Tran, N. K.; Phillips, E. J.; Mallal, S. A.; Litvan, I.; Goldman, J. G.; Alcalay, R. N.; Sidney, J.; Sulzer, D.; Sette, A.; Lindestam Arlehamn, C. S.
10.1101/2024.02.09.579465 — immunology — Posted on 2024-02-12
2975 Aligning with the predecessors and counterarguments: A systematic review of the anatomical correlates for the newly discovered meningeal layer in the existing literature
Kumar, A.; Kumar, R.; Narayan, R. K.; Nath, B.; Datusalia, A. K.; Rastogi, A. K.; Jha, R. K.; Kumar, P.; Pareek, V.; Prasoon, P.; Faiq, M. A.; Agrawal, P.; Prasad, S. N.; Kumari, C.; Asghar, A.
10.1101/2024.02.10.579742 — neuroscience — Posted on 2024-02-12
2977 Liquid footprinting: A novel approach for DNA footprinting using short double-stranded cell-free DNA from plasma
Mueller, J.; Hartwig, C.; Mirko, S.; Lisa, B.; Christopher, A.; Yevhen, V.; Karolina, G.; Sebastian, D. O.; Thorsten, B.; Georg, W. F.; Arndt, v. H.; Kai, S.
10.1101/2024.02.09.579588 — genomics — Posted on 2024-02-12
2978 Global diversity and evolution of Salmonella Panama, an understudied serovar causing gastrointestinal and invasive disease worldwide: a genomic epidemiology study
Pulford, C. V.; Perez-Sepulveda, B. M.; Ingle, D. J.; Bengtsson, R. J.; Bennet, R. J.; Rodwell, E. V.; Pardos de la Gandara, M.; Chong, C.; De Silva, P. M.; Ravel, M.; Guibert, V.; Njamkepo, E.; Hall, N.; Chattaway, M. A.; Howden, B.; Williamson, D. A.; Hinton, J. C. D.; Weill, F.-X.; Baker, K. S.
10.1101/2024.02.09.579599 — genomics — Posted on 2024-02-12
2979 Identifying Ferroptosis Inducers, HDAC, and RTK Inhibitor Sensitivity in Melanoma Subtypes through Unbiased Drug Target Prediction
Pla, I.; Szabolcs, B. L.; Peter, P. N.; Ujfaludi, Z.; Kim, Y.; Horvatovich, P.; Sanchez, A.; Pawlowski, K.; Wieslander, E.; Guedes, J.; Pal, D. M.; Ascsillan, A. A.; Betancourt, L. H.; Nemeth, I. B.; Gil, J.; Almeida, N. P. d.; Szeitz, B.; Szadai, L.; Doma, V.; Woldmar, N.; Bartha, A.; Pahi, Z.; Pankotai, T.; Gyorffy, B.; Szasz, M. A.; Domont, G.; Nogueira, F.; Kwon, H. J.; Appelqvist, R.; Karpati, S.; Fenyo, D.; Malm, J.; Varga, G. M.; Kemeny, L. V.
10.1101/2024.02.08.579424 — cancer biology — Posted on 2024-02-12
2981 Dynamic PRC1-CBX8 stabilizes a porous structure of chromatin condensates
Uckelmann, M.; Levina, V.; Taveneau, C.; Ng, X. H.; Pandey, V.; Martinez, J.; Mendiratta, S.; Houx, J.; Boudes, M.; Venugopal, H.; Trepout, S.; Zhang, Q.; Flanigan, S.; Li, M.; Sierecki, E.; Gambin, Y.; Das, P. P.; Bell, O.; de Marco, A.; Davidovich, C.
10.1101/2023.05.08.539931 — biophysics — Posted on 2024-02-12
2983 Evaluating the Benefits and Limits of Multiple Displacement Amplification with Whole-Genome Oxford Nanopore Sequencing
Dadzie, F. A.; Beaudry, M. S.; Deyanov, A.; Slanis, H.; Duong, M. Q.; Turner, R.; Khan, A.; Arias, C. A.; Kissinger, J. C.; Glenn, T. C.; de Paula Baptista, R.
10.1101/2024.02.09.579537 — bioinformatics — Posted on 2024-02-12
2988 Multiplex generation and single cell analysis of structural variants in a mammalian genome
Pinglay, S.; Lalanne, J.-B.; Daza, R. M.; Koeppel, J.; Li, X.; Lee, D. S.; Shendure, J.
10.1101/2024.01.22.576756 — genomics — Posted on 2024-02-12
2989 Arktos: a simple tool for the design of polyhedral DNA nanostructures
Balaji, H.; Samprathi, A. H.; Kolipakala, R. S.; Pradeep, P.; Nagarajan, D.
10.1101/2024.02.07.576791 — bioinformatics — Posted on 2024-02-12
2993 Natural variation in infection specificityof Caenorhabditis briggsae isolates by two RNA viruses
Alkan, C.; Bresard, G.; Frezal, L.; Richaud, A.; Ruaud, A.; Zhang, G.; Felix, M.-A.
10.1101/2024.02.10.579610 — genetics — Posted on 2024-02-12
2994 Federated Learning for multi-omics: a performance evaluation in Parkinson's disease
Danek, B. P.; Makarious, M. B.; Dadu, A.; Vitale, D.; Lee, P. S.; Nalls, M. A.; Sun, J.; Faghri, F.
10.1101/2023.10.04.560604 — bioinformatics — Posted on 2024-02-12
2996 X-chromosome loss rescues Sertoli cell maturation and spermatogenesis in Klinefelter syndrome
Winge, S. B.; Skakkebaek, N. E.; Aksglaede, L.; Saritas, G.; Rajpert-De Meyts, E.; Goossens, E.; Juul, A.; Almstrup, K.
10.1101/2024.02.09.576184 — genetics — Posted on 2024-02-12
3001 The Fossilised Birth-Death Model is Identifiable
Truman, K.; Vaughan, T. G.; Gavryushkin, A.; Gavryushkina, A.
10.1101/2024.02.08.579547 — evolutionary biology — Posted on 2024-02-12
3003 Trehalose mediates salinity-stress tolerance in a crustacean
Santos, J. L.; Nick, F.; Adhitama, N.; Fields, P. D.; Stillman, J. H.; Kato, Y. L.; Watanabe, H.; Ebert, D.
10.1101/2024.02.09.579427 — evolutionary biology — Posted on 2024-02-12
3005 Advancements in monitoring: a comparison of traditional and application-based tools for measuring outdoor recreation
Vilalta Capdevila, T.; McLellan, B. A.; Loosen, A.; Forshner, A.; Pigeon, K.; Jacob, A. L.; Wright, P.; Ehlers, L.
10.1101/2024.02.09.579662 — ecology — Posted on 2024-02-12
3006 Variable responses of individual species to tropical forest degradation
Ewers, R. M.; Pearse, W. D.; Orme, C. D. L.; Amarasekare, P.; De Lorm, T.; Granville, N.; Adzhar, R.; Aldridge, D. C.; Ancrenaz, M.; Atton, G.; Barclay, H.; Barclay, M. L.; Bernard, H.; Bicknell, J. E.; Bishop, T. R.; Blackman, J.; Both, S.; Boyle, M. W.; Brant, H.; Brasington, E.; Burslem, D.; Bush, E. R.; Calloway, K.; Carbone, C.; Cator, L.; Chapman, P. M.; Chey, V.; Chung, A.; Clare, E. L.; Cusack, J.; Dancak, M.; Davies, Z. G.; Davison, C. W.; Dawood, M. M.; Deere, N. J.; Dickinson, K. M.; Didham, R. K.; Dobert, T. F.; Dow, R. A.; Drinkwater, R.; Edwards, D. P.; Eggleton, P.; Faruk, A.; F
10.1101/2024.02.09.576668 — ecology — Posted on 2024-02-12
3007 Global niche partitioning of purine and pyrimidine cross-feeding among ocean microbes
Braakman, R.; Satinsky, B.; O'Keefe, T. J.; Longnecker, K.; Becker, J. W.; Dooley, K.; Hogle, S. L.; Arellano, A.; Kido Soule, M. C.; Kujawinski, E. B.; Chisholm, S. W.
10.1101/2024.02.09.579562 — ecology — Posted on 2024-02-12
3010 Insights into the nature of the microalgal toxins from the Chrysochromulina leadbeateri blooms in Northern Norwegian fjords
Wang, X.; Fon, M.; Andersen, A. J. C.; Solhaug, A.; Ingebrigtsen, R. A.; Samdal, I. A.; Uhlig, S.; Miles, C. O.; Edvardsen, B.; Larsen, T. O.
10.1101/2024.02.08.576530 — ecology — Posted on 2024-02-12
3011 Time-series metagenomics reveals changing protistan ecology of a temperate dimictic lake
Krinos, A. I.; Bowers, R. M.; Rohwer, R. R.; McMahon, K.; Woyke, T.; Schulz, F.
10.1101/2024.02.09.579653 — ecology — Posted on 2024-02-12
3015 Age-Related Dynamics of Methanogenic Archaea in the Human Gut Microbiome: Implications for Longevity and Health
Mohammadzadeh, R.; Mahnert, A.; Shinde, T.; Kumpitsch, C.; Weinberger, V.; Schmidt, H.; Moissl-Eichinger, C.
10.1101/2024.02.09.579604 — microbiology — Posted on 2024-02-12
3016 Nifuroxazide Suppresses PD-L1 Expression and Enhances the Efficacy of Radiotherapy in Hepatocellular Carcinoma
Zhao, T.; Wei, P.; Zhang, C.; Zhou, S.; Liang, L.; Guo, S.; Yin, Z.; Cheng, S.; Gan, Z.; Xia, Y.; Zhang, Y.; Guo, S.; Zhong, J.; Yang, Z.; Tu, F.; Wang, Q.; Bai, J.; Ren, F.; Feng, Z.; Jia, H.
10.1101/2023.09.03.556121 — immunology — Posted on 2024-02-12
3017 Integrative single-cell analysis of neural stem/progenitor cells reveals epigenetically dysregulated interferon response in progressive multiple sclerosis
Park, B.; Nicaise, A.; Tsitsipatis, D.; Pirvan, L.; Prasad, P.; Larraz Lopez De Novales, M.; Whitten, J.; Culig, L.; Llewellyn, J.; Ionescu, R.-B.; Willis, C.; Krzak, G.; Fan, J.; De, S.; Suarez Cubero, M.; Spathopoulou, A.; Peruzzotti-Jametti, L.; Leonardi, t.; Edenhofer, F.; Gorospe, M.; Mohorianu, I.; Pluchino, S.; Beerman, I.
10.1101/2024.02.09.579648 — neuroscience — Posted on 2024-02-12
3018 The highly repetitive genome of Myxobolus rasmusseni n. sp, a myxozoan parasite of fathead minnows
Muthye, V. R.; Leon Coria, A.; Liu, H.; Finney, C. A. M.; Goater, C. P.; Wasmuth, J. D.
10.1101/2024.02.09.579586 — zoology — Posted on 2024-02-12
3019 Uncovering functional lncRNAs by scRNA-seq with ELATUS
Goni, E.; Mas, A. M.; Abad, A.; Santisteban, M.; Fortes, P.; Huarte, M.; Hernaez, M.
10.1101/2024.01.26.577344 — bioinformatics — Posted on 2024-02-12
3022 Natural disaster alters the adaptive benefits of sociality in a primate
Testard, C.; Shergold, C.; Acevedo-Ithier, A.; Hart, J.; Negron-Del Valle, J.; Philips, D.; Bernau, A.; Watowich, M.; Sanguinetti-Scheck, J. I.; Montague, M.; Snyder-Mackler, N. J.; Higham, J.; Platt, M.; Brent, L. J.
10.1101/2023.07.17.549328 — animal behavior and cognition — Posted on 2024-02-12
3024 Ubiquity of inverted 'gelatinous' ecosystem pyramids in the global ocean
Lombard, F.; Guidi, L.; Brandao, M. C.; Coelho, L. P.; Colin, S.; Dolan, J. R.; Elineau, A.; Gasol, J. M.; Grondin, P. L.; Henry, N.; Ibarbalz, F. M.; Jalabert, L.; Loreau, M.; Martini, S.; Meriguet, Z.; Picheral, M.; Pierella Karlusich, J. J.; Rainer, P.; Romagnan, J.-B.; Zinger, L.; Tara Oceans Coordinators, ; Stemmann, L.; Acinas, S.; Karp-Boss, L.; Boss, E.; Sullivan, M. B.; de Vargas, C.; Bowler, C.; Karsenti, E.; Gorsky, G.
10.1101/2024.02.09.579612 — ecology — Posted on 2024-02-12
3025 Coastal marine mammal conservation using thermal imaging-based detection systems
Richter, S.; Yurk, H.; Winterl, A.; Chmelnitsky, E.; Serra-Sogas, N.; O'Hara, P. D.; Zitterbart, D. P.
10.1101/2023.08.25.554754 — ecology — Posted on 2024-02-12
3029 Cell non-autonomous signaling through the conserved C. elegans glycopeptide hormone receptor FSHR-1 regulates cholinergic neurotransmission
Buckley, M.; Jacob, W. P.; Bortey, L.; McClain, M. R.; Ritter, A. L.; Godfrey, A.; Munneke, A. S.; Ramachandran, S.; Kenis, S.; Kolnik, J. C.; Olofsson, S.; Adkins, R.; Kutoloski, T.; Rademacher, L.; Heinecke, O.; Alva, A.; Beets, I.; Francis, M.; Kowalski, J. R.
10.1101/2024.02.10.578699 — neuroscience — Posted on 2024-02-12
3031 Semi-supervised Bayesian integration of multiple spatial proteomics datasets
Coleman, S. D.; Breckels, L.; Waller, R. F.; Lilley, K. S.; Wallace, C.; Kirk, P. D. W.; Crook, O. M.
10.1101/2024.02.08.579519 — systems biology — Posted on 2024-02-12
3032 High-throughput phenotyping reveals multiple drought responses of wild and cultivated Phaseolinae beans
Verheyen, J.; Dhondt, S.; Abbeloos, R.; Eeckhout, J.; Janssens, S.; Leyns, F.; Scheldeman, X.; Storme, V.; Vandelook, F.
10.1101/2024.02.09.579595 — plant biology — Posted on 2024-02-12
3033 A Prodrug Strategy to Reposition Atovaquone as a Long-Acting Injectable for Malaria Chemoprotection
Gupta, A. K.; Eliasen, A. M.; Andahazy, W.; Zhou, F.; Henson, K.; Chi, V.; Woods, A. K.; Joseph, S. B.; Kuhen, K. L.; Wisler, J.; Ramachandruni, H.; Duffy, J.; Burrows, J. N.; Vadas, E.; Slade, A.; Schultz, P. G.; McNamara, C. W.; Chatterjee, A. K.
10.1101/2024.02.08.579395 — pharmacology and toxicology — Posted on 2024-02-12
3034 Molecular determinants of antagonist interactions with chemokine receptors CCR2 and CCR5
Dawson, J. R. D.; Wadman, G. M.; Zhang, P.; Tebben, A. J.; Carter, P. H.; Gu, S.; Shroka, T.; Borrega-Roman, L.; Salanga, C.; Handel, T. M.; Kufareva, I.
10.1101/2023.11.15.567150 — pharmacology and toxicology — Posted on 2024-02-12
3035 Loss of endogenous estrogen alters mitochondrial metabolism and muscle clock-related protein Rbm20 in female mdx mice
Timpani, C. A.; Debrincat, D.; Kourakis, S.; Boyer, R.; Formosa, L. E.; Steele, J. R.; Zhang, H.; Schittenhelm, R. B.; Russell, A. P.; Rybalka, E.; Lindsay, A.
10.1101/2024.02.08.579567 — pathology — Posted on 2024-02-12
3040 The Genotype and Phenotypes in Families (GPF) platform manages the large and complex data at SFARI
Chorbadjiev, L.; Cokol, M.; Weinstein, Z.; Shi, K.; Fleisch, C.; Dimitrov, N.; Mladenov, S.; Xu, S.; Hall, J.; Ford, S.; Lee, Y.-h.; Yamrom, B.; Marks, S.; Munoz, A.; Lash, A.; Volfovsky, N.; Iossifov, I.
10.1101/2024.02.08.579330 — bioinformatics — Posted on 2024-02-11
3041 Characterisation of RNA editing and gene therapy with a compact CRISPR-Cas13 in the retina
Kumar, S.; Hsiao, Y.-W.; Wong, V. H. Y.; Aubin, D.; Wang, J.-H.; Lisowski, L.; Rakoczy, E. P.; Li, F.; Alarcon-Martinez, L.; Gonzalez Cordero, A.; Bui, B. V.; Liu, G.-S.
10.1101/2024.02.10.579778 — molecular biology — Posted on 2024-02-11
3044 Drug-induced cytotoxicity prediction in muscle cells, an application of the Cell Painting assay
Lambert, R.; Serrano Candelas, E.; Aparicio, P.; Murphy, A.; Gozalbes, R.; Fearnhead, H. O.
10.1101/2024.02.08.579439 — bioinformatics — Posted on 2024-02-11
3046 Endothelial fatty acid-binding proteins contribute to the pathogenesis of pulmonary hypertension
Liu, B.; Yi, D.; Li, S.; Ramirez, K.; Xia, X.; Cao, Y.; Zhao, H.; Tripathi, A.; Qiu, S.; Kala, M.; Rafikov, R.; Gu, H.; Perez, V. d. j.; Lemay, S.-E.; Glembotski, C. C.; Knox, K. S.; Kalinichenko, V. V.; Bonnet, S.; Fallon, M. B.; Boucherat, O.; Dai, Z.
10.1101/2024.02.11.579846 — molecular biology — Posted on 2024-02-11
3049 Profiling IOP-responsive genes in anterior and posterior ocular tissues in the rat CEI glaucoma model
Lozano, D. C.; Yang, Y.-F.; Cepurna, W. O.; Smoody, B. F.; Ing, E.; Morrison, J. C.; Keller, K. E.
10.1101/2024.02.11.579818 — molecular biology — Posted on 2024-02-11
3050 Far-red chemigenetic biosensors for multi-dimensional and super-resolved kinase activity imaging
Frei, M. S.; Sanchez, S. A.; Liu, L.; Schneider, F.; Wang, Z.; Hakozaki, H.; Li, Y.; Lyons, A. C.; Rohm, T. V.; Olefsky, J. M.; Shi, L.; Schöneberg, J.; Fraser, S. E.; Mehta, S.; Wang, Y.; Zhang, J.
10.1101/2024.02.10.579766 — bioengineering — Posted on 2024-02-11
3051 Sarbecovirus RBD indels and specific residues dictating ACE2 multi-species adaptiveness
Si, J.; Chen, Y.; Gu, M.; Sun, Y.; Huang, M.; Shi, L.; Yu, X.; Yang, X.; Xiong, Q.; Ma, C.; Liu, P.; Shi, Z.-L.; Yan, H.
10.1101/2024.02.11.579781 — microbiology — Posted on 2024-02-11
3052 Macrolactin A Is an Inhibitor of Protein Biosynthesis in Bacteria
Vasilchenko, A. S.; Lukyanov, D. A.; Dilbaryan, D. S.; Usachev, K. S.; Poshvina, D. V.; Nikandrova, A. A.; Imamutdinova, A. N.; Garaeva, N. S.; Bikmullin, A. G.; Klochkova, E. A.; Taldaev, A.; Rusanov, A. L.; Romashin, D. D.; Luzgina, N. G.; Osterman, I. A.; Sergiev, P. V.; Teslya, A. V.
10.1101/2024.02.10.575802 — microbiology — Posted on 2024-02-11
3053 Restricting CAR T Cell Trafficking Expands Targetable Antigen Space
Morales, E. A.; Dietze, K. A.; Baker, J. M.; Wang, A.; Avila, S. V.; Iglesias, F.; Radhakrishnan, S. V.; Vander Mause, E.; Olson, M. L.; Sun, W.; Rosati, E.; Chidester, S. L.; Iraguha, T.; Fan, X.; Atanackovic, D.; Luetkens, T.
10.1101/2024.02.08.579002 — bioengineering — Posted on 2024-02-11
3054 Microsporidian coinfection reduces fitness of a fungal pathogen due to rapid host mortality
Dziuba, M. K.; McIntire, K. M.; Davenport, E. S.; Baird, E.; Huerta, C.; Jaye, R.; Corcoran, F. E.; McCreadie, P.; Nelson, T.; Duffy, M. A.
10.1101/2024.02.08.579564 — ecology — Posted on 2024-02-11
3056 Congenital T cell activation impairs transitional to follicular B cell maturation in humans
Allard-Chamard, H.; Hillier, K.; Ramseier, M. L.; Bertocchi, A.; Kaneko, N.; Premo, K.; Lam, T.; Yuen, G.; Karpel, M.; Mahajan, V. S.; Tsekeri, C.; Vencic, J.; Crotty, R.; Sharda, A.; Barmettler, S.; Westermann-Clark, E.; Walter, J. E.; Ghebremichael, M.; Shalek, A. K.; Farmer, J. R.; Pillai, S.
10.1101/2024.02.08.579495 — immunology — Posted on 2024-02-11
3058 navigate: an open-source platform for smart light-sheet microscopy.
Marin, Z.; Wang, X.; Collison, D. W.; McFadden, C.; Lin, J.; Borges, H.; Chen, B.; Mehra, D.; Shen, Q.; Galecki, S.; Daetwyler, S.; Fiolka, R. P.; Dean, K. M.
10.1101/2024.02.09.579083 — biophysics — Posted on 2024-02-11
3059 Conformational basis of subtype-specific allosteric control of NMDA receptor gating
Bleier, J.; Ribeiro Furtado de Mendonca, P.; Habrian, C.; Stanley, C.; Vyklicky, V.; Isacoff, E. Y.
10.1101/2024.02.10.579740 — biophysics — Posted on 2024-02-11
3061 Phospho-KNL-1 recognition by a TPR domain targets the BUB-1/BUB-3 complex to C. elegans kinetochores
Houston, J.; Vissotsky, C.; Deep, A.; Hakozaki, H.; Crews, E.; Oegema, K.; Corbett, K. D.; Lara-Gonzalez, P.; Kim, T.; Desai, A.
10.1101/2024.02.09.579536 — cell biology — Posted on 2024-02-11
3064 Substrate recognition principles for PP2A-B55
Kruse, T.; Garvanska, D.; Varga, J. K.; Garland, W.; McEwan, B.; Hein, J.; Weisser, M. B.; Brandies Puy, I.; Chan, C.; Parrila, P. S.; Lopez-Mendez, B.; Jeyaprakash, A. A.; Schueler-Furman, O.; Jensen, T. H.; Kettenbach, A.; Nilsson, J.
10.1101/2024.02.10.579793 — cell biology — Posted on 2024-02-11
3065 Interactors and effects of overexpressing YlxR/RpnM, a conserved RNA binding protein in cyanobacteria
Hemm, L.; Miucci, A.; Riediger, M.; Tholen, S.; Kraus, A.; Georg, J.; Schilling, O.; Hess, W. R.
10.1101/2024.01.06.574455 — microbiology — Posted on 2024-02-11
3066 αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation
Uboveja, A.; Huang, Z.; Buj, R.; Amalric, A.; Wang, H.; Tangudu, N. K.; Cole, A. R.; Megill, E.; Kantner, D.; Chatoff, A.; Ahmad, H.; Marcinkiewicz, M. M.; Disharoon, J. A.; Graff, S.; Dahl, E. S.; Hempel, N.; Stallaert, W.; Sidoli, S.; Bitler, B. G.; Long, D. T.; Snyder, N. W.; Aird, K. M.
10.1101/2024.02.06.578742 — cancer biology — Posted on 2024-02-11
3067 Dual Targeting of Histone Deacetylases and MYC as Potential Treatment Strategy for H3-K27M Pediatric Gliomas
Algranati, D.; Oren, R.; Dassa, B.; Fellus-Alyagor, L.; Plotnikov, A.; Barr, H.; Harmelin, A.; London, N.; Ron, G.; Furth, N.; Shema, E.
10.1101/2024.02.05.578974 — cancer biology — Posted on 2024-02-11
3068 VHL Mutation Drives Human Clear Cell Renal Cell Carcinoma Progression Through PI3K/AKT-Dependent Cholesteryl Ester Accumulation
Zhang, S.; Fang, T.; He, Y.; Feng, W.; Yu, Z.; Zheng, Y.; Zhang, C.; Hu, S.; Liu, Z.; Liu, J.; Yu, J.; Zhang, H.; He, A.; Gong, Y.; He, Z.; Yang, K.; Xi, Z.; Yu, W.; Zhou, L.; Yao, L.; Yue, S.
10.1101/2023.01.02.522447 — cancer biology — Posted on 2024-02-11
3070 Mitochondrial mutation spectrum in Chordates: damage versus replication signatures, causes, and dynamics
Iliushchenko, D.; Efimenko, B.; Mikhailova, A. G.; Shamanskiy, V.; Saparbaev, M.; Mazunin, I.; Knorre, D.; Kunz, W.; Kapranov, P.; Denisov, S.; Khrapko, K.; Fellay, J.; Gunbin, K.; Popadin, K.
10.1101/2023.12.08.570826 — bioinformatics — Posted on 2024-02-11
3073 Collapse of late endosomal pH elicits a rapid Rab7 response via V-ATPase and RILP.
Mulligan, R. J.; Magaj, M. M.; Digilio, L.; Redemann, S.; Yap, C. C.; Winckler, B.
10.1101/2023.10.24.563658 — cell biology — Posted on 2024-02-11
3075 Increased Cholesterol Synthesis Drives Neurotoxicity in Patient Stem Cell-Derived Model of Multiple Sclerosis
Ionescu, R.-B.; Nicaise, A. M.; Reisz, J. A.; Williams, E. C.; Prasad, P.; Dzieciatkowska, M.; Stephenson, D.; Suarez Cubero, M.; Pirvan, L.; Willis, C. M.; Peruzzotti-Jametti, L.; Fossati, V.; Edenhofer, F.; Leonardi, t.; Frezza, C.; Mohorianu, I.; D'Alessandro, A.; Pluchino, S.
10.1101/2024.01.16.575826 — neuroscience — Posted on 2024-02-11
3077 Neuroprotection of low dose carbon monoxide in Parkinson's disease models commensurate with the reduced risk of Parkinson's among smokers
Rose, K. N.; Zorlu, M.; Xue, X.; Fassini, A.; Cai, W.; Lin, S.; Webb, P. K.; Schwarzschild, M.; Chen, X.; Gomperts, S. N.
10.1101/2023.05.27.542565 — neuroscience — Posted on 2024-02-11
3078 A comprehensive study of light quality acclimation in Synechocystis sp.PCC 6803
Zavrel, T.; Segecova, A.; Kovacs, L.; Lukes, M.; Novak, Z.; Pohland, A. C.; Szabo, M.; Somogyi, B.; Prasil, O.; Cerveny, J.; Bernat, G.
10.1101/2023.06.08.544187 — plant biology — Posted on 2024-02-11
3079 Biomolecular condensates form spatially inhomogeneous network fluids
Dar, F.; Cohen, S. R.; Mitrea, D. M.; Phillips, A. H.; Nagy, G.; Leite, W. C.; Stanley, C. B.; Choi, J.-M.; Kriwacki, R. W.; Pappu, R. V.
10.1101/2023.10.07.561338 — biophysics — Posted on 2024-02-11
3081 Exploring the impact of interthalamic adhesion on human cognition: insights from healthy subjects and thalamic stroke patients
Vidal, J. P.; Rachita, K.; Servais, A.; Peran, P.; Pariente, J.; Bonneville, F.; Albucher, J.-F.; Danet, L.; Barbeau, E. J.
10.1101/2024.02.08.579448 — neuroscience — Posted on 2024-02-11
3082 The Mouse Inferior Colliculus Responds Preferentially to Non-Ultrasonic Vocalizations
Tehrani, M.; Shanbhag, S.; Huyck, J.; Patel, R.; Kazimierski, D.; Wenstrup, J.
10.1101/2024.02.09.579664 — neuroscience — Posted on 2024-02-11
3083 DHCR24-mediated sterol homeostasis during spermatogenesis is required for sperm mitochondrial sheath formation and impacts male fertility over time
Relovska, S.; Wang, H.; Zhang, X.; Fernandez-Tussy, P.; Jeong, K.; Choi, J.; Suarez, Y.; McDonald, J.; Fernandez-Hernando, C.; Chung, J.-J.
10.1101/2023.12.21.572851 — cell biology — Posted on 2024-02-11
3087 A non-invasive method to sample immune cells in the lower female genital tract using menstrual discs
Peters, M. Q.; Domenjo-Vila, E.; Carlson, M.; Armistead, B.; Edlefsen, P. T.; Gasper, M.; Dabee, S.; Whidbey, C.; Jaspan, H. B.; Prlic, M.; Harrington, W. E.
10.1101/2023.11.16.567469 — immunology — Posted on 2024-02-11
3089 Spatial interactions modulate tumor growth and immune infiltration
Marzban, S.; Srivastava, S.; Kartika, S.; Bravo, R.; Safriel, R.; Zarski, A.; Anderson, A. R. A.; Chung, C. H.; Amelio, A. L.; West, J.
10.1101/2024.01.10.575036 — cancer biology — Posted on 2024-02-11
3090 ZNF251 haploinsufficiency confers PARP inhibitors resistance in BRCA1-mutated cancer cells through modulation of RAD51 and DNA-PKcs-dependent pathways
Li, H.; Chatla, S.; Liu, X.; Tian, Z.; Vekariya, U.; Wang, P.; Kim, D.; Octaviani, S.; Walt, M.; Lian, Z.; Morton, G.; Feng, Z.; Yang, D.; Yang, D.; Liu, H.; Sullivan-Reed, K.; Childers, W.; Yu, X.; Chitrala, K. N.; Madzo, J.; Skorski, T.; Huang, J.
10.1101/2022.09.29.510119 — cancer biology — Posted on 2024-02-11
3092 Fascin structural plasticity mediates flexible actin bundle construction
Gong, R.; Reynolds, M. J.; Carney, K. R.; Hamilton, K.; Bidone, T. C.; Alushin, G. M.
10.1101/2024.01.03.574123 — biophysics — Posted on 2024-02-11
3095 Mitochondrial DNA copy number reduction via in vitro TFAM knockout remodels the nuclear epigenome and transcriptome
Nguyen, J.; Win, P. W.; Nagano, T. S.; Shin, E. H.; Newcomb, C.; Arking, D. E.; Castellani, C. A.
10.1101/2024.01.29.577835 — genomics — Posted on 2024-02-11
3097 Spatially resolved human kidney multi-omics single cell atlas highlights the key role of the fibrotic microenvironment in kidney disease progression
Abedini, A.; Levinsohn, J. L.; Kloetzer, K.; Dumoulin, B.; Ma, Z.; Frederick, J.; Dhillon, P.; S. Balzer, M.; Shrestha, R.; Liu, H.; Vitale, S.; Devalaraja-Narashimha, K.; Grandi, P.; Bhattacharyya, T.; Hu, E.; S. Pullen, S.; M Boustany-Kari, C.; Guarnieri, P.; Karihaloo, A.; Trum, D.; Yan, H.; Coleman, K.; Palmer, M.; Sarov-Blat, L.; Morton, L.; A. Hunter, C.; Kaestner, K. H.; Li, M.; Susztak, K.
10.1101/2022.10.24.513598 — genetics — Posted on 2024-02-11
3100 Switch-Like Phosphorylation of WRN Integrates End-Resection with RAD51 Metabolism at Collapsed Replication Forks
Palermo, V.; Malacaria, E.; Semproni, M.; Perdichizzi, B.; Valenzisi, P.; Sanchez, M.; Marini, F.; Pellicioli, A.; Franchitto, A.; Pichierri, P.
10.1101/403808 — cell biology — Posted on 2024-02-11
3101 SHIELD: Skull-shaped hemispheric implants enabling large-scale-electrophysiology datasets in the mouse brain
Bennett, C.; Ouellette, B.; Ramirez, T. K.; Cahoon, A.; Cabasco, H.; Browning, Y.; Lakunina, A.; Lynch, G. F.; McBride, E.; Belski, H.; Gillis, R.; Grasso, C.; Howard, R.; Johnson, T.; Loeffler, H.; Smith, H.; Sullivan, D.; Williford, A.; Caldejon, S.; Durand, S.; Gale, S. D.; Guthrie, A.; Ha, V.; Han, W.; Hardcastle, B.; Mochizuki, C.; Sridhar, A.; Suarez, L.; Swapp, J.; Wilkes, J.; Siegle, J. H.; Farrell, C.; Groblewski, P.; Olsen, S.
10.1101/2023.11.12.566771 — neuroscience — Posted on 2024-02-11
3103 Integrative single-cell analysis of neural stem/progenitor cells reveals epigenetically dysregulated interferon response in progressive multiple sclerosis
Park, B.; Nicaise, A.; Tsitsipatis, D.; Pirvan, L.; Prasad, P.; Larraz Lopez De Novales, M.; Whitten, J.; Culig, L.; Llewellyn, J.; Ionescu, R.-B.; Willis, C.; Krzak, G.; Fan, J.; De, S.; Suarez Cubero, M.; Spathopoulou, A.; Peruzzotti-Jametti, L.; Leonardi, t.; Edenhofer, F.; Gorospe, M.; Mohorianu, I.; Pluchino, S.; Beerman, I.
10.1101/2024.02.09.579648 — neuroscience — Posted on 2024-02-11
3105 40 Hz Steady-State Response in Human Auditory Cortex Is Shaped by GABAergic Neuronal Inhibition
Toso, A.; Wermuth, A. P.; Arazi, A.; Braun, A.; Grent-'t Jong, T.; Uhlhaas, P. J.; Donner, T. H.
10.1101/2023.10.20.563259 — neuroscience — Posted on 2024-02-11
3108 Integrating single-cell RNA-seq datasets with substantial batch effects
Hrovatin, K.; Moinfar, A. A.; Zappia, L.; Tejada Lapuerta, A.; Lengerich, B.; Kellis, M.; Theis, F. J.
10.1101/2023.11.03.565463 — bioinformatics — Posted on 2024-02-10
3109 Fragle: Universal ctDNA quantification using deep learning of fragmentomic profiles
Jacobsen Skanderup, A.; Zhu, G.; Rahman, C.; Getty, V.; Baruah, P.; Carrie, H.; Lim, A.; Guo, Y. A.; Poh, Z.; Sim, N.; Abdelmoneim, A.; Cai, Y.; Ho, D.; Thangaraju, S.; Poon, P.; Lau, Y.; Gan, A.; Ng, S.; Odinokov, D.; Koo, S.-L.; Chong, D.; Tay, B.; Tan, T.; Yap, Y.; Chok, A.; Ng, M.; Tan, P.; Tan, D.; Wong, L.; Wong, P.; Tan, I.
10.1101/2023.07.28.550922 — bioinformatics — Posted on 2024-02-11
3111 Large-scale characterization of drug mechanism of action using proteome-wide thermal shift assays
Van Vranken, J. G.; Li, J.; Mintseris, J.; Gadzuk-Shea, M.; Gygi, S. P.; Schweppe, D.
10.1101/2024.01.26.577428 — biochemistry — Posted on 2024-02-10
3113 Considerations for reporting variants in novel candidate genes identified during clinical genomic testing
Chong, J. X.-L.; Berger, S.; Baxter, S.; Smith, E.; Xiao, C.; Calame, D.; Hawley, M.; Rivera-Munoz, E. A.; DiTroia, S.; Genomics Research to Elucidate the Genetics of Rare Diseases (GREGoR) Consortium, ; Bamshad, M.; Rehm, H.
10.1101/2024.02.05.579012 — genetics — Posted on 2024-02-11
3116 Lesions in a songbird vocal circuit increase variability in song syntax
Koparkar, A.; Warren, T. L.; Charlesworth, J. D.; Shin, S.; Brainard, M. S.; Veit, L.
10.1101/2023.07.25.550508 — neuroscience — Posted on 2024-02-10
3117 Neurofeedback training can modulate task-relevant memory replay in rats
Gillespie, A. K.; Astudillo Maya, D. A.; Denovellis, E. L.; Desse, S.; Frank, L. M.
10.1101/2022.10.13.512183 — neuroscience — Posted on 2024-02-11
3118 The spatial landscape of glial pathology and T-cell response in Parkinson's disease substantia nigra
Jakubiak, K.; Paryani, F.; Kannan, A.; Lee, J.; Madden, N.; Li, J.; Chen, D.; Mahajan, A.; Xia, S.; Flowers, X.; Menon, V.; Sulzer, D.; Goldman, J. E.; Sims, P. A.; Al-Dalahmah, O.
10.1101/2024.01.08.574736 — neuroscience — Posted on 2024-02-11
3122 Infection-on-Chip: an in vitro human vessel to study Neisseria meningitidis colonization and vascular damages
Pinon, L.; Chabaud, M.; Nivoit, P.; Wong-Ng, J.; Nguyen, T.-T.; Paul, V.; Goussard, S.; Frachon, E.; Obino, D.; Gobaa, S.; Dumenil, G.
10.1101/2024.02.09.579276 — synthetic biology — Posted on 2024-02-10
3123 The ideotype for drought tolerance in bioenergy Populus nigra
Smith, H. K.; Puertolas, J.; Douthe, C.; Emiliani, G.; Giovannelli, A.; Rowland, L. S.; Allwright, M.; Bailey-Bale, J. H.; Valdes-Fragoso, P. M.; Larsen, E. K.; Alberti, G.; Zaldei, A.; Hirons, A. D.; Alasia, F.; Ribas-Carbo, M.; Flexas, J.; Dodd, I. C.; Davies, W. J.; Taylor, G.
10.1101/2024.02.07.579233 — plant biology — Posted on 2024-02-10
3124 Anti-diuretic hormone ITP signals via a guanylate cyclase receptor to modulate systemic homeostasis in Drosophila
Gera, J.; Agard, M.; Nave, H.; Sajadi, F.; Thorat, L.; Kondo, S.; Nassel, D.; Paluzzi, J.-P. V.; Zandawala, M.
10.1101/2024.02.07.579245 — physiology — Posted on 2024-02-10
3126 A common set of structurally distinct endogenous retroviruses predict survival in multiple human tumor types
Massa, A. L.; Chintalapudi, H.; Coppenbarger, E. C.; Peterson, J. M.; Moss, W. N.; Frost, H. R.; Leach, S. D.
10.1101/2024.02.07.579350 — cancer biology — Posted on 2024-02-10
3133 Structural characterization of the ACDC domain from ApiAP2 proteins of the malaria parasite
Le Berre, M.; Tubiana, T.; Reutersward Waldner, P.; Lazar, N.; Gallay Li de la Sierra, I.; Santos, J. M.; Llinas, M.; Nessler, S.
10.1101/2024.02.09.579679 — biochemistry — Posted on 2024-02-10
3134 Structure-based design of a soluble human cytomegalovirus glycoprotein B antigen stabilized in a prefusion-like conformation
Sponholtz, M. R.; Byrne, P. O.; Lee, A. G.; Ramamohan, A. R.; Goldsmith, J. A.; McCool, R. S.; Zhou, L.; Johnson, N. V.; Hsieh, C.-L.; Connors, M.; Karthigeyan, K.; Campbell, J. D.; Permar, S. R.; Maynard, J. A.; Yu, D.; Bottomley, M. J.; McLellan, J. S.
10.1101/2024.02.10.579772 — molecular biology — Posted on 2024-02-10
3135 Androgens at the skin surface regulate S. aureus pathogenesis through the activation of agr quorum sensing
John, M. S.; Chinnappan, M.; Artami, M.; Bhattacharya, M.; Keogh, R.; Kavanaugh, J.; Sharma, T.; Horswill, A. R.; Harris-Tryon, T. A.
10.1101/2024.02.10.579753 — microbiology — Posted on 2024-02-10
3139 Temporal Dynamics of Cyanobacterial Bloom Community Composition and Toxin Production from Urban Lakes
Maurer, J. A.; Kim, A. M.; Oblie, N.; Hefferan, S.; Xie, H.; Slitt, A.; Jenkins, B. D.; Bertin, M. J.
10.1101/2024.02.07.579333 — pharmacology and toxicology — Posted on 2024-02-10
3142 Determining susceptibility loci in triple negative breast cancer using a novel pre-clinical model
Simon, S. E.; Simmons, B. W.; Kim, M.; Joseph, S. C.; Korba, E.; Marathe, S. J.; Bohm, M. S.; Mahajan, S.; Bohl, C.; Read, R.; Holt, J.; Hayes, N.; Lu, L.; Williams, R.; Sipe, L.; Ashbrook, D. G.; Makowski, L.
10.1101/2024.02.08.579359 — genetics — Posted on 2024-02-10
3146 Phylogenetic analysis of Mycobacterium bovis Reveals Evidence Of Animal And Zoonotic Tuberculosis Transmission Between Morocco And European Countries
Yahyaoui Azami, H.; Perea, C.; Stuber, T.; Bouslikhane, M.; Berrada, J.; Aboukhassib, H.; Allepuz Palau, A. O.; Reis, A. C.; Cunha, M. V.; Thacker, T. C.; Robbe-Austerman, S.; Salvador, L. C.; Quinn, F.
10.1101/2024.02.09.579592 — molecular biology — Posted on 2024-02-10
3149 Protective function and differentiation cues of brain-resident CD8+ T cells during immune surveillance of chronic latent Toxoplasma gondii infection
Porte, R.; Belloy, M.; Audibert, A.; Bassot, E.; Aida, A.; Alis, M.; Miranda-Capet, R.; Jourdes, A.; van Gisbergen, K. P.; Masson, F.; Blanchard, N.
10.1101/2024.02.08.579453 — immunology — Posted on 2024-02-10
3150 Structural insights into CXCR4 modulation and oligomerization
Saotome, K.; McGoldrick, L. L.; Ho, J.-H.; Ramlall, T. F.; Shah, S.; Moore, M. J.; Kim, J. H.; Leidich, R.; Olson, W. C.; Franklin, M. C.
10.1101/2024.02.09.579708 — biochemistry — Posted on 2024-02-10
3151 SARS-COV-2 induces blood-brain barrier and choroid plexus barrier impairments and vascular inflammation in mice
Qiao, H.; Deng, X.; Qiu, L.; Qu, Y.; Chiu, Y.; Chen, F.; Xia, S.; Muenzel, C.; Ge, T.; Song, P.; Bonnin, A.; Zhao, Z.; Yuan, W.
10.1101/2024.02.09.579589 — neuroscience — Posted on 2024-02-10
3152 CoCoPyE: feature engineering for learning and prediction of genome quality indices
Birth, N.; Leppich, N.; Schirmacher, J.; Andreae, N.; Steinkamp, R.; Blanke, M.; Meinicke, P.
10.1101/2024.02.07.579156 — bioinformatics — Posted on 2024-02-10
3154 scSpatialSIM: a simulator of spatial single-cell molecular data
Soupir, A. C.; Wrobel, J.; Creed, J. H.; Ospina, O. E.; Wilson, C. M.; Manley, B. J.; Peres, L. C.; Fridley, B. L.
10.1101/2024.02.08.579486 — cell biology — Posted on 2024-02-10
3155 A lentiviral toolkit to monitor airway epithelial cell differentiation using bioluminescence
Orr, J. C.; Laali, A.; Durrenberger, P. F.; Lazarus, K. A.; El Mdawar, M.-B.; Janes, S. M.; Hynds, R. E.
10.1101/2024.02.09.579635 — cell biology — Posted on 2024-02-10
3156 Clearance of protein aggregates during cell division
Du, S.; Wang, Y.; Chen, B.; Xie, S.; Chan, K. Y.; Hay, D. C.; Chew, T. G.
10.1101/2024.02.10.579754 — cell biology — Posted on 2024-02-10
3157 Selective Translation Orchestrates Key Signaling Pathways in Primed Pluripotency
Okubo, C.; Nakamura, M.; Sato, M.; Shichino, Y.; Mito, M.; Takashima, Y.; Iwasaki, S.; Takahashi, K.
10.1101/2024.02.09.579580 — cell biology — Posted on 2024-02-10
3159 Gene regulatory network landscape of Group 3/4 medulloblastoma
Joshi, P.; Stelzer, T.; Okonechnikov, K.; Sarropoulos, I.; Sepp, M.; Pour-Jamnani, M. V.; Rademacher, A.; Yamada-Saito, T.; Schneider, C.; Schmidt, J.; Schaefer, P.; Leiss, K.; Bortolomeazzi, M.; Mallm, J.-P.; da Silva, P. B. G.; Statz, B.; Wittmann, A.; Schramm, K.; Blattner-Johnson, M.; Fiesel, P.; Jones, B.; Milde, T.; Pajtler, K.; van Tilburg, C. M.; Witt, O.; Rippe, K.; Korshunov, A.; Jones, D. T. W.; Hovestadt, V.; Northcott, P. A.; Thongjuea, S.; Jaeger, N.; Kaessmann, H.; Pfister, S. M.; Kutscher, L. M.
10.1101/2024.02.09.579680 — cancer biology — Posted on 2024-02-10
3164 Effective lowering of α-synuclein expression by targeting G-quadruplex structures within the SNCA genome
Pirota, V.; Rey, F.; Fantini, V.; Esposito, L.; Pandini, C.; Di Gerlando, R.; Doria, F.; Mella, M.; Pansarasa, O.; Gandellini, P.; Freccero, M.; Carelli, S.; Cereda, C.
10.1101/2024.02.09.579657 — molecular biology — Posted on 2024-02-09
3168 Characterization of Neisseria gonorrhoeae colonization of macrophages under distinct polarization states and nutrients environment
Juarez Rodriguez, M. D.; Marquette, M.; Youngblood, R.; Dhungel, N.; Torres Escobar, A.; Ivanov, S. S.; Dragoi, A.-M.
10.1101/2024.02.08.579566 — microbiology — Posted on 2024-02-09
3172 Focused ultrasound increases gene delivery to deep brain structure following the administration of a recombinant adeno-associated virus in the cerebrospinal fluid
Kofoed, R. H.; Noseworthy, K.; Wu, K.; Vecchio, L. M.; Dibia, C. L.; Sivadas, S.; Wu, S.-K.; Mikloska, K.; White, M.; Elmer, B.; Ramachandran, S.; Mueller, C.; Hynynen, K.; Aubert, I.
10.1101/2024.02.09.579587 — neuroscience — Posted on 2024-02-09
3173 Functional genomic screening in Komagataella phaffii enabled by high-activity CRISPR-Cas9 library
Tafrishi, A.; Trivedi, V.; Xing, Z.; Li, M.; Mewalal, R.; Cutler, S.; Blaby, I.; Wheeldon, I.
10.1101/2024.02.08.579509 — systems biology — Posted on 2024-02-09
3176 Olive mill solid waste induces beneficial mushroom-specialized metabolite diversity: a computational metabolomics study.
Khatib, S.; Pereman, I.; Kostanda, E.; Zdouc, M. M.; Ezov, N.; Schweitzer, R.; van der Hooft, J. J. J.
10.1101/2024.02.09.579616 — biochemistry — Posted on 2024-02-09
3180 Structures of the Foamy virus fusion protein reveal an unexpected link with the F protein of paramyxo- and pneumoviruses
Fernandez, I.; Bontems, F.; Brun, D.; Coquin, Y.; Goverde, C. A.; Correia, B. E.; Gessain, A.; Buseyne, F.; Rey, F. A.; Backovic, M.
10.1101/2024.02.09.579661 — microbiology — Posted on 2024-02-09
3184 Serological screening in animals combined with environmental surveys provides definite proof of the local establishment of Burkholderia pseudomallei in Guadeloupe
Gasque, M.; Guernier-Cambert, V.; Manuel, G.; Aaziz, R.; Terret, J.; Deshayes, T.; Baudrimont, X.; Breurec, S.; Rochelle-Newall, E.; Laroucau, K.
10.1101/2024.02.09.579440 — microbiology — Posted on 2024-02-09
3187 Brain signal complexity and aperiodicity predict human corticospinal excitability
Frohlich, J.; Ruch, S.; Trunk, B. H.; Keute, M.; Mediano, P. A. M.; Gharabaghi, A.
10.1101/2024.02.09.579457 — neuroscience — Posted on 2024-02-09
3189 Integrative single-cell analysis of neural stem/progenitor cells reveals epigenetically dysregulated interferon response in progressive multiple sclerosis
Park, B.; Nicaise, A.; Tsitsipatis, D.; Pirvan, L.; Prasad, P.; Larraz Lopez De Novales, M.; Whitten, J.; Culig, L.; Llewellyn, J.; Ionescu, R.-B.; Willis, C.; Krzak, G.; Fan, J.; De, S.; Suarez Cubero, M.; Spathopoulou, A.; Peruzzotti-Jametti, L.; Leonardi, t.; Edenhofer, F.; Gorospe, M.; Pluchino, S.; Beerman, I.
10.1101/2024.02.09.579648 — neuroscience — Posted on 2024-02-09
3190 Fine-grained neural coding of bodies and body parts in human visual cortex
Garcia Ramirez, J.; Vanhoyland, M.; Apurva Murty, R. N.; Decramer, T.; Van Paesschen, W.; Bracci, S.; Op de Beeck, H.; Kanwisher, N. G.; Janssen, P.; Theys, T.
10.1101/2024.02.09.579107 — neuroscience — Posted on 2024-02-09
3192 A paternal cardiac lesion induces cardiac adaptation in offspring
Coppe, B.; Galardi-Castilla, M.; Sanz-Morejon, A.; Arora, P.; Lucas, J.; Lalaguna, L.; Lara Pezzi, E.; Flores, I.; Mercader, N.
10.1101/2024.02.09.579452 — developmental biology — Posted on 2024-02-09
3193 Minimum Effective Dose of Clemastine in a Mouse Model of Preterm White Matter Injury
Odell, E. P.; Jabassini, N.; Schniedewind, B.; Pease-Raissi, S. E.; Frymoyer, A.; Christians, U.; Green, A. J.; Chan, J. R.; Ostrem, B. E. L.
10.1101/2024.02.08.578953 — neuroscience — Posted on 2024-02-09
3194 Upregulation of the Proto-Oncogene Src Kinase in Alzheimer's Disease: From Molecular Interactions to Therapeutic Potential
Mastroeni, D.; Chan, C. K.; Morshed, N.; Diouf, D.; de Avila, C.; Suazo, C.; Nolz, J.; Lopatin, U.; Wang, Q.; Serrano, G.; Beach, T.; Dunkley, T.; Jensen, K.; Van Den Hove, D.; White, F. M.; Chiu, P.-L.; Singharoy, A.; Reiman, E. M.; Readhead, B. P.
10.1101/2024.02.07.579336 — neuroscience — Posted on 2024-02-09
3195 ChineseEEG: A Chinese Linguistic Corpora EEG Dataset for Semantic Alignment and Neural Decoding
Mou, X.; He, C.; Tan, L.; Yu, J.; Liang, H.; Zhang, J.; Tian, Y.; Yang, Y.; Xu, T.; Wang, Q.; Cao, M.; Chen, Z.; Hu, C.; Wang, X.; Liu, Q.; Wu, H.
10.1101/2024.02.08.579481 — neuroscience — Posted on 2024-02-09
3198 The role of cortistatin in neuroimmune dysregulation underlying ischemic stroke
Castillo-Gonzalez, J.; Buscemi, L.; Vargas-Rodriguez, P.; Serrano-Martinez, I.; Forte-Lago, I.; Price-Hirt, M.; Hernandez-Cortes, P.; Hirt, L.; Gonzalez-Rey, E.
10.1101/2024.02.07.579281 — immunology — Posted on 2024-02-09
3199 ABCC10 roles in plant development and the transport of indole-3-butyric acid
Homayouni, A.; Damodaran, S.; Schreiber, K.; Michniewicz, M.; Gunther, L.; Strader, L. C.
10.1101/2024.02.07.579300 — plant biology — Posted on 2024-02-09
3200 Large- and Small-Animal Studies of Safety, Pharmacokinetics (PK), and Biodistribution of Inflammasome-Targeting Nanoligomer in the Brain and Other Target Organs
Risen, S.; Kusick, B.; Sharma, S.; Gilberto, V.; Brindley, S.; Aguilar, M.; Brown, J.; McGrath, S.; Chatterjee, A.; Moreno, J.; Nagpal, P.
10.1101/2024.02.07.579323 — pharmacology and toxicology — Posted on 2024-02-09
3202 Ligand-induced conformational changes in the β1-Adrenergic Receptor Revealed by Hydrogen-Deuterium Exchange Mass Spectrometry
Toporowska, J.; Kapoor, P.; Musgaard, M.; Gherbi, K.; Sengmany, K.; Qu, F.; Soave, M.; Yen, H.-Y.; Hansen, K.; Jazayeri, A.; Hopper, J. T. S.; Politis, A.
10.1101/2024.02.07.579309 — biophysics — Posted on 2024-02-09
3203 In Vivo Plasmonic Enhancement of the Photocycle Dynamics and Fluorescence of Genetically Encoded Voltage Indicators
Locarno, M.; Dong, Q.; Meng, X.; Glessi, C.; Hettema, N.; Brandsma, N.; Blokhuizen, S.; Castaneda, A.; Schmidt, T.; Ganapathy, S.; Post, M.; van Roemburg, L.; Xu, B.; Cho, C.-T.; Laan, L.; Chien, M.-P.; Brinks, D.
10.1101/2024.02.07.579195 — biophysics — Posted on 2024-02-09
3204 A single giant cell at the origin of an evolutionary innovation
Badiane, A.; Viala, S.; Armisen, D.; Mignerey, I.; Forcet-Vauchel, C.; De Jesus Villanueva, C. N.; Van Belleghem, S.; Crumiere, A.; Santos, E.; Francesconi, M.; Khila, A.
10.1101/2024.02.08.579433 — evolutionary biology — Posted on 2024-02-09
3205 The intensity of supplementary feeding in an urban environment impacts overwintering Mallards Anas platyrchynhos as wintering conditions get harsher
Witkowska, M.; Wesolowski, W.; Martyna Markiewicz, ; Jonasz Pakizer, ; Julia Neumann, ; Ozarowska, A.; Meissner, W.
10.1101/2024.02.07.579312 — ecology — Posted on 2024-02-09
3206 Effects of satellite-linked telemetry tags on humpback whales in the Gulf of Maine: photographic assessment of tag sites
Gulland, F. M. D.; Robbins, J.; Zerbini, A. N.; Andrews-Goff, V.; Berube, M.; Clapham, P. J.; Double, M.; Gales, N.; Kennedy, A. S.; Landry, S.; Mattila, D. K.; Sandilands, D.; Tackaberry, J. E.; Uhart, M. M.; Vanstreels, R. E. T.
10.1101/2024.02.07.579298 — ecology — Posted on 2024-02-09
3207 Systematic Analysis of Immune Changes after B-cell Depletion in Autoimmune Multiple Sclerosis
Wei, J.; Moon, J.; Yasumizu, Y.; Zhang, L.; Radassi, K.; Buitrago-Pocasangre, N.; Deerhake, M. E.; Strauli, N.; Chan, A.; Herman, A.; Pedotte, R.; Raposo, C.; Tackenberg, B.; Yim, I.; Pappalardo, J.; Longbrake, E. E.; Sumida, T. S.; Axisa, P.-P.; Hafler, D. A.
10.1101/2024.02.07.576204 — immunology — Posted on 2024-02-09
3210 Surface adhesion and membrane fluctuations influence the elastic modulus of extracellular vesicles
Stridfeldt, F.; Kylhammar, H.; Metem, P.; Pandey, V.; Agrawal, V.; Gorgens, A.; Mamand, D. R.; Gustafsson, O.; El Andaloussi, S.; Mitra, D.; Dev, A.
10.1101/2024.02.07.578591 — biophysics — Posted on 2024-02-09
3211 Modified histone peptides uniquely tune the material properties of HP1α condensates.
Deshpande, P.; Prentice, E.; Vidal Ceballos, A.; Casaccia, P.; Elbaum-Garfinkle, S.
10.1101/2024.02.07.579285 — biophysics — Posted on 2024-02-09
3213 Considerations for reporting variants in novel candidate genes identified during clinical genomic testing
Chong, J. X.-L.; Berger, S.; Baxter, S.; Smith, E.; Xiao, C.; Calame, D.; Hawley, M.; Rivera-Munoz, E. A.; DiTroia, S.; Genomics Research to Elucidate the Genetics of Rare Diseases (GREGoR) Consortium, ; Bamshad, M.; Rehm, H.
10.1101/2024.02.05.579012 — genetics — Posted on 2024-02-09
3215 A genome wide search for non-additive allele effects identifies PSKH2 as involved in the variability of Factor V activity.
Gendre, B.; Martinez-Perez, A.; Kleber, M. E.; van Hylckama Vlieg, A.; Boland, A.; Olaso, R.; Germain, M.; Munsch, G.; Moissl, A. P.; Suchon, P.; Souto, J. C.; Soria Fernandez, J. m.; Deleuze, J.-F.; Marz, W.; Rosendaal, F.; Sabater-Lleal, M.; Morange, P. E.; Tregouet, D.-A.
10.1101/2024.02.08.579474 — genetics — Posted on 2024-02-09
3216 First evidence for the evolution of host manipulation by tumors during the long-term vertical transmission of tumor cells in Hydra oligactis
BOUTRY, J.; Oceane, R.; Lena, G.; Jordan, M.; Aurora, N.; Sophie, T.; Beata, U.; Rodrigo, H.; Antoine, D. M.; Jacint, T.; Frederic, T.
10.1101/2024.02.08.579507 — evolutionary biology — Posted on 2024-02-09
3219 Viral delivery of compact CRISPR-Cas12f for in vivo gene editing applications
Sharrar, A.; Meacham, Z.; Staples-Ager, J.; Arake de Tacca, L.; Rabuka, D.; Collingwood, T.; Schelle, M.
10.1101/2024.02.06.578965 — molecular biology — Posted on 2024-02-09
3220 PP2A catalytic subunit alpha is critically required for CD8+ T cell homeostasis and anti-bacterial responses
Zeng, H.; Zhou, X.; Li, M.; Ai, M.; Li, Y.; Zhu, X.; Hansen, M. J.; Zhong, J.; Johnson, K. L.; Zenka, R.; Pandey, A.; Pease, L. R.
10.1101/2024.02.06.578745 — immunology — Posted on 2024-02-09
3221 From connectome to effectome: learning the causal interaction map of the fly brain
Pospisil, D. A.; Aragon, M. J.; Dorkenwald, S.; Matsliah, A.; Sterling, A. R.; Schlegel, P.; Yu, S.-c.; McKellar, C. M.; Costa, M.; Eichler, K.; Jefferis, G. S. X. E.; Murthy, M.; Pillow, J. W.
10.1101/2023.10.31.564922 — neuroscience — Posted on 2024-02-09
3222 Unfolded Von Willebrand Factor Binds Protein S and Reduces Anticoagulant Activity
Sim, M. M. S.; Mollica, M. Y.; Alfar, H. R.; Hollifield, M.; Chung, D. W.; Fu, X.; Gandhapudi, S.; Coenen, D. M.; Prakhya, K. S.; Mahmood, D. F. D.; Banerjee, M.; Peng, C.; Li, X.; Thornton, A. C.; Porterfield, J. Z.; Sturgill, J. L.; Sievert, G. A.; Barton-Baxter, M.; Zheng, Z.; Campbell, K. S.; Woodward, J. G.; Lopez, J. A.; Whiteheart, S. W.; Garvy, B. A.; Wood, J. P.
10.1101/2024.02.08.579463 — biochemistry — Posted on 2024-02-09
3223 Differential tissue deformability underlies shape divergence of the embryonic brain and spinal cord under fluid pressure
McLaren, S. B. P.; Xue, S.-L.; Ding, S.; Winkel, A.; Baldwin, O.; Dwarakacherla, S.; Franze, K.; Hannezo, E.; Xiong, F.
10.1101/2024.01.12.575349 — developmental biology — Posted on 2024-02-09
3225 Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86/JN.1 lineages combining increased fitness and antibody evasion
Planas, D.; Staropoli, I.; Michel, V.; Lemoine, F.; Donati, F.; Prot, M.; Porrot, F.; Benhassine, F. G.; Jeyarajah, B.; Brisebarre, A.; Dehan, O.; Avon, L.; Bolland, W.; Hubert, M.; Buchreiser, J.; Vanhoucke, T.; Rosenbaum, P.; Veyer, D.; Pere, H.; Lina, B.; Assant, S. T.; Hocqueloux, L.; Prazuck, T.; Loriere, E. S.; Schwartz, O.
10.1101/2023.11.20.567873 — microbiology — Posted on 2024-02-09
3228 Loss of function in RBBP5 results in a syndromic neurodevelopmental disorder associated with microcephaly
Huang, Y.; Jay, K. L.; Huang, A. Y.-W.; Wan, J.; Jangam, S. V.; Chorin, O.; Rothschild, A.; Barel, O.; Mariani, M.; Xue, H.; Huang, J.; Iascone, M.; Mignot, C.; Undiagnosed Diseases Network, ; Keren, B.; Saillour, V.; Mah-Som, A. Y.; Sacharow, S.; Rajabi, F.; Costin, C.; Yamamoto, S.; Kanca, O.; Bellen, H. J.; Rosenfeld, J. A.; Palmer, C. G.; Nelson, S.; Wangler, M. F.; Martinez-Agosto, J. A.
10.1101/2024.02.06.578086 — genetics — Posted on 2024-02-09
3230 Emergent collective alignment gives competitive advantage to longer cells during range expansion
van den Berg, N.; Thijssen, K.; Nguyen, T. T.; Sarlet, A.; Cordero, M.; Vazquez, A. G.; Mitarai, N.; Doostmohammadi, A.; Jauffred, L.
10.1101/2024.01.26.577059 — biophysics — Posted on 2024-02-09
3234 LSD Modulates Proteins Involved in Cell Proteostasis, Energy Metabolism and Neuroplasticity in Human Brain Organoids
Costa, M. d. N.; Goto-Silva, L.; Nascimento, J. M.; Domith, I.; Karmirian, K.; Feilding, A.; Trindade, P.; Martins-de-Souza, D.; Rehen, S. K.
10.1101/2024.01.30.577659 — neuroscience — Posted on 2024-02-09
3236 Improving generalizability for MHC-I binding peptide predictions through geometric deep learning
Marzella, D. F.; Crocioni, G.; Radusinovic, T.; Lepikhov, D.; Severin, H.; Bodor, D. L.; Rademaker, D. T.; Lin, C.; Georgievska, S.; Renaud, N.; Kessler, A. L.; Lopez-Tarifa, P.; Buschow, S.; Bekkers, E.; Xue, L. C.
10.1101/2023.12.04.569776 — bioinformatics — Posted on 2024-02-09
3238 Higher-order combinatorial chromatin perturbations by engineered CRISPR-Cas12a for functional genomics
Hsiung, C. C.- S.; Wilson, C. M.; Sambold, N. A.; Dai, R.; Chen, Q.; Misiukiewicz, S.; Arab, A.; Teyssier, N.; O'Loughlin, T.; Cofsky, J.; Shi, J.; Gilbert, L. A.
10.1101/2023.09.18.558350 — genetics — Posted on 2024-02-09
3240 Setdb1 safeguards genome integrity in muscle stem cells to allow for regenerative myogenesis and inflammation
Garcia, P.; Jarassier, W.; Brun, C.; Giordani, L.; Agostini, F.; Kung, W. H.; Peccate, C.; Ravent, J.; Fall, S.; Petit, V.; Cheung, T.; Ait-Si-Ali, S.; Le Grand, F.
10.1101/2023.06.08.544190 — cell biology — Posted on 2024-02-09
3241 S-nitrosylation of EZH2 at C329 and C700 interplay with PRC2 complex assembly, methyltransferase activity, and EZH2 stability to regulate endothelial functions
Sakhuja, A.; Katakia, Y. T.; Tripathi, S. M.; Bhattacharya, R.; Thakkar, N. P.; Ramakrishnan, S.; Chakraborty, S.; Thakar, S.; Sundriyal, S.; Chowdhury, S.; Majumder, S.
10.1101/2024.02.06.579117 — cell biology — Posted on 2024-02-09
3242 Disentangling abiotic and biotic effects of treated wastewater on stream biofilm resistomes enables the discovery of a new planctomycete beta-lactamase
Attrah, M.; Schaerer, M. R.; Esposito, M.; Gionchetta, G.; Buergmann, H.; Lens, P. N. L.; Fenner, K.; van de Vossenberg, J.; Robinson, S. L.
10.1101/2023.11.20.567610 — microbiology — Posted on 2024-02-09
3243 Specific interaction between Group B Streptococcus CC17 hypervirulent clone and phagocytes
Bourrel, A.-S.; Picart, A.; Fernandez, J.-C.; Hays, C.; Saubamea, B.; Mignon, V.; Poyart, C.; Tazi, A.; Guignot, J.
10.1101/2022.12.02.518834 — microbiology — Posted on 2024-02-09
3244 Glial expression of Drosophila UBE3A causes spontaneous seizures modulated by 5-HT signaling
Sleep, M.; Landaverde, S.; Lacoste, A.; Tan, S.; Schuback, R.; Reiter, L.; Iyengar, A.
10.1101/2024.02.08.579543 — neuroscience — Posted on 2024-02-09
3245 Peripheral insulin resistance attenuates cerebral glucose metabolism and impairs working memory in healthy adults
Deery, H.; Liang, E.; Di Paolo, R. A.; Voigt, K.; Murray, G.; Siddiqui, N.; Moran, C.; Egan, G.; Jamadar, S. D.
10.1101/2023.09.08.556948 — neuroscience — Posted on 2024-02-09
3247 Species-conserved mechanisms of abstract rule learning promote cognitive flexibility in complex environments
Baehner, F.; Popov, T.; Boehme, N.; Hermann, S.; Merten, T.; Zingone, H.; Koppe, G.; Meyer-Lindenberg, A.; Toutounji, H.; Durstewitz, D.
10.1101/2022.11.14.516439 — neuroscience — Posted on 2024-02-09
3249 Nanoligomers targeting NF-κB and NLRP3 reduce neuroinflammation and improve cognitive function with aging and tauopathy
Wahl, D.; Risen, S. J.; Osburn, S. C.; Emge, T.; Sharma, S.; Gilberto, V. S.; Chatterjee, A.; Nagpal, P.; Moreno, J. A.; LaRocca, T. J.
10.1101/2024.02.03.578493 — physiology — Posted on 2024-02-09
3251 GEMCAT - A new algorithm for gene expression-based prediction of metabolic alterations
Sharma, S.; Sauter, R.; Hotze, M.; Prowatke, A. M. P.; Niere, M.; Kipura, T.; Egger, A.-S.; Thedieck, K.; Kwiatkowski, M.; Ziegler, M.; Heiland, I.
10.1101/2024.01.15.575710 — bioinformatics — Posted on 2024-02-09
3253 Contextualising samples: Supporting reference genomes of European biodiversity through sample and associated metadata collection
Boehne, A.; Fernandez, R.; Leonard, J. A.; McCartney, A. M.; McTaggart, S.; Melo-Ferreira, J.; Monteiro, R.; Oomen, R. A.; Vinnere Pettersson, O.; Struck, T. H.
10.1101/2023.06.28.546652 — genomics — Posted on 2024-02-09
3254 Cost-effectiveness of Precision Guided SIT for Control of Anopheles gambiae in the Upper River Region, The Gambia.
Gendron, W. A. C.; Raban, R.; Mondal, A.; Sanchez C., H. M.; Smidler, A.; Zilberman, D.; Ilboudo, P. G.; D'Alessandro, U.; Marshall, J. M.; Akbari, O. S.
10.1101/2023.07.20.549762 — genetics — Posted on 2024-02-09
3255 Associations between common genetic variants and income provide insights about the socioeconomic health gradient
Kweon, H.; Burik, C. A. P.; Ning, Y.; Ahlskog, R.; Xia, C.; Abner, E.; Bao, Y.; Bhatta, L.; Faquih, T.; Feijter, M.; Fisher, P.; Gelemanovic, A.; Giannelis, A.; Hottenga, J.-J.; Khalili, B.; Lee, Y.; Li-Gao, R.; Masso, J.; Myhre, R.; Palviainen, T.; Rietveld, C. A. P.; Teumer, A.; Verweij, R. M.; Willoughby, E. A.; Agerbo, E.; Bergmann, S.; Boomsma, D. I.; Borglum, A. D.; Brumpton, B. M.; Davies, N. M.; Esko, T.; Gordon, S. D.; Homuth, G.; Ikram, A.; Johannesson, M.; Kaprio, J.; Kidd, M. P.; Kutalik, Z.; Kwong, A. S. F.; Lee, J.; Luik, A.; Mook-Kanamori, D. O.; Magnus, P.; Marques-Vidal, P.; M
10.1101/2024.01.09.574865 — genetics — Posted on 2024-02-09
3257 Novel reassortments of variation underlie repeated adaptation to whole genome duplication in two outcrossing Arabidopsis species
Bohutinska, M.; Petrikova, E.; Booker, T. R.; Vives Cobo, C.; Vlcek, J.; Sramkova, G.; Postulkova, A.; Hojka, J.; Marhold, K.; Kolar, F.; Yant, L.; Schmickl, R.
10.1101/2023.01.11.523565 — evolutionary biology — Posted on 2024-02-09
3258 Deciphering deep-sea chemosynthetic symbiosis by single-nucleus RNA-sequencing
Wang, H.; He, K.; Zhang, H.; Zhang, Q.; Cao, L.; Li, J.; Zhong, Z.; Chen, H.; Zhou, L.; Lian, C.; Wang, M.; Chen, K.; Qian, P.-Y.; Li, C.
10.1101/2023.05.29.542712 — ecology — Posted on 2024-02-09
3259 A Bayesian analysis of birth pulse effects on the probability of detecting Ebola virus in fruit bats
Pleydell, D. R. J.; Ndong Bass, I.; Mba Djondzo, F. A.; Meta Djomsi, D.; Kouanfack, C.; Peeters, M.; Cappelle, J.
10.1101/2023.08.10.552777 — ecology — Posted on 2024-02-09
3261 Loss of the mitochondrial citrate carrier, SLC25A1/CIC disrupts embryogenesis via 2-Hydroxyglutarate
Kasprzyk-Pawelec, A.; Tan, M.; Phua, Y.-L.; Rahhal, R.; McIntosh, A.; Fernandez, H.; Mosaoa, R.; Cheema, A.; Jiang, L.; Popratiloff, A.; Clarkson, C.; Pearson, G. W.; Glasgow, E.; Albanese, C.; Vockley, J.; Avantaggiati, M. L.
10.1101/2023.07.18.549409 — developmental biology — Posted on 2024-02-09
3263 BMP9 and BMP10 coordinate liver cellular crosstalk to maintain liver health
Zhao, D.; Huang, Z.; Li, X.; Wang, H.; Hou, Q.; Wang, Y.; Yan, F.; Yang, W.; Liu, D.; Yi, S.; Han, C.; Hao, Y.; Tang, L.
10.1101/2024.02.08.579542 — cell biology — Posted on 2024-02-09
3265 Ramping dynamics in the frontal cortex unfold over multiple timescales during motor planning
Affan, R. O.; Bright, I. M.; Pemberton, L.; Cruzado, N. A.; Scott, B. B.; Howard, M. W.
10.1101/2024.02.05.578819 — neuroscience — Posted on 2024-02-09
3266 Goal-directed motor actions drive acetylcholine dynamics in sensory cortex
Zou, J.; Willem de Gee, J.; Mridha, Z.; Trinh, S.; Erskine, A.; Jing, M.; Yao, J.; Walker, S.; Li, Y.; McGinley, M.; Hires, S. A.
10.1101/2021.12.21.473699 — neuroscience — Posted on 2024-02-09
3268 RNA Splicing Junction Landscape Reveals Abundant Tumor-Specific Transcripts in Human Cancer
Li, Q.; li, Z.; Chen, B.; Zhao, J.; Yu, H.; Hu, J.; Lai, H.; Zhang, H.; Li, Y.; Meng, Z.; Hu, Z.; Huang, S.
10.1101/2024.02.06.579246 — cancer biology — Posted on 2024-02-09
3269 Dual Targeting of Histone Deacetylases and MYC as Potential Treatment Strategy for H3-K27M Pediatric Gliomas
Algranati, D.; Oren, R.; Dassa, B.; Fellus-Alyagor, L.; Plotnikov, A.; Barr, H.; Harmelin, A.; London, N.; Ron, G.; Furth, N.; Shema, E.
10.1101/2024.02.05.578974 — cancer biology — Posted on 2024-02-09
3270 Dominant suppressor genes of p53-induced apoptosis in Drosophila melanogaster
Lukacsovich, T.; Szlanka, T.; Balint, E.; Szabo, K.; Hajdu, I.; Molnar, E.; Viragh, E.; Lin, Y. H.; Mehi, O.; Zvara, A.; Török, I.; Hegedüs, Z.; Kiss, B.; Ramasz, B.; Magdalena, L. M.; Puskas, L.; Bernard, M. M.; Fonagy, A.; Asztalos, Z.; Zurovec, M.; Boros, I.; Kiss, I.
10.1101/2024.02.06.579196 — genetics — Posted on 2024-02-09
3272 BEND2 is a crucial player in oogenesis and reproductive aging
Huang, Y.; Bucevic, N.; Coves, C.; Felipe-Medina, N.; Marcet-Ortega, M.; Nikou, N.; Madrid-Sandin, C.; Ferrer Miralles, N.; Iborra, A.; Pendas, A. M.; Roig, I.
10.1101/2024.02.06.579114 — cell biology — Posted on 2024-02-09
3278 Global diversity, recurrent evolution, and recent selection on amylase structural haplotypes in humans
Bolognini, D.; Halgren, A. S.; Lou, R. N.; Raveane, A.; Rocha, J.; Guarracino, A.; Soranzo, N.; Chin, J.; Garrison, E.; Sudmant, P. H.
10.1101/2024.02.07.579378 — evolutionary biology — Posted on 2024-02-09
3280 Geographically widespread and novel hemotropic mycoplasmas and bartonellae in Mexican free-tailed bats and sympatric North American bat species
Becker, D.; Dyer, K.; Lock, L.; Pladas, S.; Sukhadia, A.; Demory, B.; Nunes Batista, J.; Pineda, M.; Simmons, N.; Adams, A.; Frick, W.; O'Mara, T.; Volokhov, D.
10.1101/2024.02.08.577874 — ecology — Posted on 2024-02-09
3282 Cocaine sensitization in male rats requires activation of estrogen receptors
Menendez-Delmestre, R.; Agosto-Rivera, J. L.; Gonzalez-Segarra, A. J.; Segarra, A. C.
10.1101/2024.02.07.579327 — neuroscience — Posted on 2024-02-09
3286 The domesticated transposon protein L1TD1 associates with its ancestor L1 ORF1p to promote LINE-1 retrotransposition
Kavaklioglu, G.; Podhornik, A.; Vcelkova, T.; Marjanovic, J.; Beck, M. A.; Phan-Canh, T.; Mair, T.; Miccolo, C.; Drino, A.; Egger, G.; Chiocca, S.; Modic, M.; Seiser, C.
10.1101/2024.02.01.577722 — genetics — Posted on 2024-02-09
3289 Consequences of Cancer on Zebrafish Danio rerio: Insights into Sex Determination, Sex Ratio, and Offspring Survival.
Boutry, J.; Douhard, M.; Asselin, K.; Dujon, A. M.; Meliani, J.; De Backer, O.; Nicolas, D.; Shultz, A. G.; Biro, P. A.; Beckmann, C.; Fontenille, L.; Kissa, K.; Ujvari, B.; Thomas, F.
10.1101/2024.02.08.579516 — evolutionary biology — Posted on 2024-02-09
3291 Enhanced Branched-Chain Amino Acid Metabolism Improves Age-related Reproductive Function
Lesnik, C.; Kaletsky, R.; Ashraf, J.; Sohrabi, S.; Cota, V.; Sengupta, T.; Keyes, W.; Luo, S.; Murphy, C. T.
10.1101/2023.02.09.527915 — cell biology — Posted on 2024-02-09
3292 YraN is a helicase-associated nuclease fostering extended recombination events by natural transformation
Hardy, L.; Plantade, J.; Morales, V.; Mazzamurro, F.; Rocha, E. P. C.; Polard, P.; Charpentier, X.
10.1101/2024.02.06.579203 — microbiology — Posted on 2024-02-09
3295 Mosaic sarbecovirus vaccination elicits cross-reactive responses in pre-immunized animals
Cohen, A. A.; Keeffe, J. R.; Schiepers, A.; Dross, S. E.; Greaney, A. J.; Rorick, A. V.; Gao, H.; Gnanapragasam, P. N. P.; Fan, C.; West, A. P.; Ramsingh, A. I.; Erasmus, J. H.; Pata, J. D.; Muramatsu, H.; Pardi, N.; Lin, P. J. C.; Baxter, S.; Cruz, R.; Quintanar-Audelo, M.; Robb, E.; Serrano-Amatriain, C.; Magneschi, L.; Fotheringham, I. G.; Fuller, D. H.; Victora, G. D.; Bjorkman, P. J.
10.1101/2024.02.08.576722 — immunology — Posted on 2024-02-09
3296 Potent AMA1-specific human monoclonal antibody against P. vivax Pre-erythrocytic and Blood Stages
Winnicki, A. C.; King, C. L.; Bosch, J.; Malachin, A. N.; Carias, L. L.; Skomorovska-Prokvolit, Y.; Tham, W.-H.; Dietrich, M. H.; Popovici, J.; Roobsoong, W.; Beeson, J. G.; Sattabongkot, J.; Yeoh, L. M.; Opi, D. H.; Feufack-Donfack, L. B.; Orban, A.; Drago, C. L.; McLaine, O. S.; Redinger, K. R.; Jung, N. C.; Baldor, L.
10.1101/2024.02.07.579302 — immunology — Posted on 2024-02-09
3299 Mapping Serotonergic Dynamics using Drug-Modulated Molecular Connectivity
Ionescu, T. M.; Amend, M.; Hafiz, R.; Maurer, A.; Biswal, B. B.; Wehrl, H. F.; Herfert, K.
10.1101/2024.02.08.579462 — neuroscience — Posted on 2024-02-09
3301 Microglia-astrocyte crosstalk regulates synapse remodeling via Wnt signaling
Faust, T. E.; Lee, Y.-H.; O'Connor, C. D.; Boyle, M. A.; Gunner, G.; Badimon, A.; Ayata, P. E.; Schaefer, A.; Schafer, D. P.
10.1101/2024.02.08.579178 — neuroscience — Posted on 2024-02-09
3302 Zebrafish models of candidate human epilepsy-associated genes provide evidence of hyperexcitability
Lacoursiere, C.; Ullmann, J. F. P.; Koh, H. Y.; Turner, L.; Baker, C. M.; Robens, B.; Shao, W.; Rotenberg, A.; McGraw, C. M.; Poduri, A.
10.1101/2024.02.07.579190 — genetics — Posted on 2024-02-08
3304 Multimodal Hox5 activity generates motor neuron diversity
KC, R.; Lopez de Boer, R.; Lin, M.; Jeannotte, L.; Philippidou, P.
10.1101/2024.02.08.579338 — developmental biology — Posted on 2024-02-09
3305 Novel 3D Approach to Model Non-Alcoholic Fatty Liver Disease using human Pluripotent Stem Cells
Morell, C. M.; Tilson, S. G.; Tomaz, R. A.; Shahsavari, A.; Munteanu, A.; Canu, G.; Wesley, B. T.; Perrin, M.; Geti, I.; Mukhopadhyay, S.; Mazzacuva, F.; Gissen, P.; Garcia-Bernardo, J.; Bachman, M.; Rimland, C. A.; Sampaziotis, F.; Mohorianu, I.; Vallier, L.
10.1101/2024.02.07.579290 — cell biology — Posted on 2024-02-08
3306 Genome-wide transcriptional silencing and mRNA stabilization allow the coordinated expression of the meiotic program in mice
Bellutti, L.; Peng, E. C. S.; Guerquin, M.-J.; Messiaen, S.; Llano, E.; Cluzet, V.; Dereli, I.; Rolland, A. D.; Martini, E.; Toth, A.; Pendas, A. M.; Chalmel, F.; Livera, G.
10.1101/2024.02.08.579523 — cell biology — Posted on 2024-02-08
3308 Targeted Dab2 Restoration: A Novel Approach for Enhanced Wound Healing in Diabetic Conditions
Bhattacharjee, S.; Wu, H.; Wang, B.; Cui, K.; Eisa-Beygi, S.; Wang, D.; Cowan, D. B.; Wong, S.; Shi, J.; Chen, H.
10.1101/2024.02.07.579019 — cell biology — Posted on 2024-02-09
3312 Local and global changes in cell density induce reorganisation of 3D packing in a proliferating epithelium.
Barone, V.; Tagua, A.; Andres-San Roman, J. A.; Hamdoun, A.; Garrido-Garcia, J.; Lyons, D.; Escudero, L. M.
10.1101/2024.02.08.579268 — developmental biology — Posted on 2024-02-08
3313 A systems-based approach to uterine fibroids identifies differential splicing associated with abnormal uterine bleeding
Wang, C.-Y.; Philpott, M.; O'Brien, D. P.; Ndungu, A. P.; Malzahn, J.; Maritati, M.; Mehta, N.; Gamble, V.; Martinez-Burgo, B.; Bonham, S.; Fischer, R.; Garbutt, K.; Becker, C. M.; Manek, S.; Harris, A. L.; Sacher, F.; Obendorf, M.; Schmidt, N.; Müller, J.; Zollner, T. M.; Zondervan, K. T.; Kessler, B. M.; Oppermann, U.; Cribbs, A. P.
10.1101/2024.02.06.578872 — systems biology — Posted on 2024-02-08
3314 Spatially Exploring RNA Biology in Archival Formalin-Fixed Paraffin-Embedded Tissues
Bai, Z.; Zhang, D.; Gao, Y.; Tao, B.; Bao, S.; Enninful, A.; Zhang, D.; Su, G.; Tian, X.; Zhang, N.; Xiao, Y.; Liu, Y.; Gerstein, M.; Li, M.; Xing, Y.; Lu, J.; Xu, M. L.; Fan, R.
10.1101/2024.02.06.579143 — systems biology — Posted on 2024-02-08
3316 CausalXtract: a flexible pipeline to extract causal effects from live-cell time-lapse imaging data
Simon, F.; Comes, M. C.; Tocci, T.; Dupuis, L.; Cabeli, V.; Lagrange, N.; Mencattini, A.; Parrini, M. C.; Martinelli, E.; Isambert, H.
10.1101/2024.02.06.579177 — systems biology — Posted on 2024-02-08
3318 Microbial Electrosynthesis from CO2 reaches Productivity of 1 Syngas and Chain Elongation Fermentations
Cabau-Peinado, O.; Winkelhorst, M.; Stroek, R.; de Kat Angelino, R.; Straathof, A.; Masania, K.; Daran, J.-M. G.; Jourdin, L.
10.1101/2024.02.08.579422 — bioengineering — Posted on 2024-02-08
3319 Circadian period is compensated for repressor protein turnover rates in single cells
Gabriel, C. H.; del Olmo, M. H.; Widini, A. R.; Roshanbin, R.; Woyde, J.; Hamza, E.; Gutu, N.-N.; Zehtabian, A.; Ewers, H.; Granada, A. E.; Herzel, H.; Kramer, A.
10.1101/2024.02.06.579141 — cell biology — Posted on 2024-02-08
3321 Mycobacterium ulcerans challenge strain selection for a Buruli ulcer controlled human infection model
Muhi, S.; Buultjens, A. H.; Porter, J. L.; Marshall, J. L.; Doerflinger, M.; Pidot, S. J.; O'Brien, D.; Johnson, P. D. R.; Lavender, C.; Globan, M.; McCarthy, J.; Osowicki, J.; Stinear, T. P.
10.1101/2024.02.08.579445 — microbiology — Posted on 2024-02-08
3322 Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex
Williams, B. G.; King, L. D. W.; Pulido, D.; Quinker, D.; Lias, A. M.; Silk, S. E.; Ragotte, R. J.; Davies, H.; Barrett, J. R.; McHugh, K.; Rigby, C. A.; Alanine, D. G. W.; Barfod, L.; Shea, M. W.; Cowley, L. A.; Dabbs, R. A.; Pattinson, D. J.; Douglas, A. D.; Lyth, O. R.; Illingworth, J. K.; Jin, J.; Carnot, C.; Kotraiah, V.; Christen, J. M.; Noe, A. R.; MacGill, R. S.; King, C. R.; Birkett, A. J.; Soisson, L. A.; Skinner, K.; Miura, K.; Long, C. A.; Higgins, M. K.; Draper, S. J.
10.1101/2024.02.08.579322 — immunology — Posted on 2024-02-08
3325 Transport mechanism of DgoT, a bacterial homolog of SLC17 organic anion transporters
Dmitrieva, N.; Gholami, S.; Alleva, C.; Carloni, P.; Alfonso-Prieto, M.; Fahlke, C.
10.1101/2024.02.07.579339 — biophysics — Posted on 2024-02-08
3326 Time-varying mediation analysis for incomplete data with application to DNA methylation study for PTSD
Wei, K.; Xue, F.; Xu, Q.; Yuan, Y.; Zhang, Y.; Qin, G.; Wani, A. H.; Aiello, A. E.; Wildman, D. E.; Uddin, M.; Qu, A.
10.1101/2024.02.06.579228 — bioinformatics — Posted on 2024-02-08
3327 GenomeFace: a deep learning-based metagenome binner trained on 43,000 microbial genomes
Lettich, R.; Egan, R.; Riley, R.; Wang, Z.; Tritt, A.; Oliker, L.; Yelick, K.; Buluc, A.
10.1101/2024.02.07.579326 — bioinformatics — Posted on 2024-02-08
3328 Invariant sets for switched systems to tackle bacterial resistance
Anderson, A.; Kinahan, M. W.; Gonzalez, A. H.; Udekwu, K.; Hernandez-Vargas, E. A.
10.1101/2024.02.06.579227 — bioinformatics — Posted on 2024-02-08
3334 Electrospun Poly(ε-caprolactone) Membranes Modified with Heparin and Essential Fatty Acids for Biomedical Applications
Farias, T.; Ricardo, J.; Cunha, J.; Bracelay, Y. R.; Dip, A.; Bastos, I.; Segala, K.; Junior, J. S.; Talu, s.; Paula, M.; Brito, W.
10.1101/2024.02.08.579539 — bioengineering — Posted on 2024-02-08
3337 STREAMLINED PROTEOME-WIDE IDENTIFICATION OF DRUG TARGETS INDICATES ORGAN-SPECIFIC ENGAGEMENT
Batth, T. S.; Locard-Paulet, M.; Doncheva, N. T.; Lopez-Mendez, B.; Jensen, L. J.; Olsen, J. V.
10.1101/2024.02.08.578880 — biochemistry — Posted on 2024-02-08
3338 Direct delivery of stabilized Cas-embedded base editors achieves efficient and accurate editing of clinically relevant targets
Lee, J. M.; Zeng, J.; Liu, P.; Nguyen, M. A.; Loustaunau, D. S.; Bauer, D.; Yilmaz, N. K.; Wolfe, S.; Schiffer, C. A.
10.1101/2024.02.08.579528 — biochemistry — Posted on 2024-02-08
3341 DNA methylation modulates nucleosome retention in sperm and H3K4 methylation deposition in early mouse embryos.
Fanourgakis, G.; Gaspa-Toneu, L.; Komarov, P. A.; Ozonov, E. A.; Smallwood, S. A.; Peters, A. H. F. M.
10.1101/2024.02.06.579069 — genetics — Posted on 2024-02-08
3346 An iPSC-derived bio-inspired scaffold modelling the structure and the effects of extracellular matrix in cardiac fibrosis
Niro, F.; Fernandes, S.; Cassani, M.; Apostolico, M.; Oliver-De La Cruz, J.; Pereira-Sousa, D.; Pagliari, S.; Vinarsky, V.; Zdrahal, Z.; Potesil, D.; Pustka, V.; Pompilio, G.; Sommariva, E.; Rovina, D.; Maione, A. S.; Bersanini, L.; Becker, M.; Rasponi, M.; Forte, G.
10.1101/2024.02.07.578948 — cell biology — Posted on 2024-02-08
3349 A meta-analysis of the gut microbiome in inflammatory bowel disease patients identifies disease-associated small molecules
Elmassry, M. M.; Sugihara, K.; Chankhamjon, P.; Camacho, F. R.; Wang, S.; Sugimoto, Y.; Chatterjee, S.; Chen, L. A.; Kamada, N.; Donia, M. S.
10.1101/2024.02.07.579278 — microbiology — Posted on 2024-02-08
3351 Unveiling the regulatory network controlling natural transformation in lactococci
Toussaint, F.; Henry de Frahan, M.; Poncelet, F.; Ladriere, J.-M.; Horvath, P.; Fremaux, C.; Hols, P.
10.1101/2024.02.08.579460 — microbiology — Posted on 2024-02-08
3352 Site-specific sulfations regulate the physicochemical properties of papillomavirus-heparan sulfate interactions for entry
Bano, F.; Soria Martinez, L.; van Bodegraven, D.; Thorsteinsson, K.; Brown, A. M.; Fels, I.; Snyder, N. L.; Bally, M.; Schelhaas, M.
10.1101/2024.02.08.579286 — microbiology — Posted on 2024-02-08
3354 MatP delays the segregation of chromosome termini independently of cell division and tetramer formation in Vibrio cholerae
Espinosa, E.; Challita, J.; Desfontaines, J.-M.; Possoz, C.; Val, M.-E.; Mazel, D.; Marbouty, M.; Koszul, R.; Galli, E.; Barre, F. X.
10.1101/2024.02.08.578905 — microbiology — Posted on 2024-02-08
3355 Diversity of Vibrio cholerae O1 through the human gastrointestinal tract during cholera
Lypaczewski, P.; Chac, D.; Dunmire, C. N.; Tandoc, K. M.; Chowdhury, F.; Khan, A. I.; Bhuiyan, T.; Harris, J. B.; LaRocque, R. C.; Calderwood, S. B.; Ryan, E. T.; Qadri, F.; Shapiro, B. J.; Weil, A. A.
10.1101/2024.02.08.579476 — microbiology — Posted on 2024-02-08
3356 Degradation of indole-3-acetic acid by plant-associated microbes
WANG, L.; Liu, Y.; Ni, H.; Zuo, W.; Shi, H.; Liao, W.; Liu, H.; Bai, Y.; Yue, H.; Huang, A.; Friedman, J.; Si, T.; Liu, Y.; Chen, M.; Dai, L.
10.1101/2024.02.08.579438 — microbiology — Posted on 2024-02-08
3357 The signature of a T-cell response to KSHV persists across space and time in individuals with epidemic and endemic KS from Uganda
Ravishankar, S.; Towlerton, A. M. H.; Mooka, P.; Kafeero, J.; Coffey, D. G.; Aicher, L. D.; Mubiru, K. R.; Okoche, L.; Atwinirembabazi, P.; Okonye, J.; Phipps, W. T.; Warren, E. H.
10.1101/2024.02.06.579223 — immunology — Posted on 2024-02-08
3358 Model-guided metabolic engineering of curcuminoid Production in Pseudomonas putida
Martin-Pascual, M.; Moreno-Paz, S.; Van Rosmalen, R. P.; Dorigo, J.; Demaria, F.; Van Kranenburg, R.; Martins dos Santos, V.; Suarez-Diez, M. S.
10.1101/2024.02.08.579459 — synthetic biology — Posted on 2024-02-08
3362 Arabidopsis GENOMES UNCOUPLED PROTEIN1 binds to plastid RNAs and promotes their maturation
Tang, Q.; Xu, D.; Lenzen, B.; Brachmann, A.; Yapa, M. M.; Doroodian, P.; Schmitz-Linneweber, C.; Masuda, T.; Hua, Z.; Leister, D.; Kleine, T.
10.1101/2024.02.08.579428 — plant biology — Posted on 2024-02-08
3363 Dual action of sphinganine in the plant disease resistance to bacteria.
Huby, E.; Villaume, S.; Chemotti, C.; Dorey, S.; Cordelier, S.; Crouzet, J.; Gilliard, G.; Terryn, C.; Berquand, A.; Herrfurth, C.; Feussner, I.; Jacquard, C.; Fontaine, F.; Clement, C.; Baillieul, F.; Deleu, M.; Cordelier, S.
10.1101/2024.02.07.579277 — plant biology — Posted on 2024-02-08
3364 Loop-mediated Isothermal Amplification (LAMP) assay for reliable detection of Xanthomonas axonopodis pv. vasculorum
Marabella, M.; Howard, J.; Bhandari, S.; Do, S.; Montoya-Pimolwatana, M.; Dou, Y.; Dobhal, S.; Arizala, D.; Montesinos, S.; Andreason, S. A.; Ochoa-Corona, F. M.; Bingham, J.-P.; Odani, J.; Jenkins, D.; Ma, L. M.; Fletcher, J.; Stack, J. P.; Arif, M.
10.1101/2024.02.07.579270 — plant biology — Posted on 2024-02-08
3365 Cardiac Magnetic Resonance Studies in a Large Animal Model that Simulates the Cardiac Abnormalities of Human Septic Shock
Ford, V. J.; Applefeld, W. N.; Wang, J.; Sun, J.; Solomon, S. B.; Sidenko, S.; Feng, J.; Sheffield, C.; Klein, H. G.; Yu, Z.-X.; TORABI-PARIZI, P.; Danner, R. L.; Sachdev, V.; Solomon, M. A.; Chen, M. Y.; Natanson, C.
10.1101/2024.02.05.578971 — physiology — Posted on 2024-02-08
3367 Inhibition of ULK1/2 and KRASG12C controls tumor growth in preclinical models of lung cancer
McMahon, M.; Ghazi, P. C.; O'Toole, K. T.; Srinivas Boggaram, S.; Scherzer, M. T.; Silvis, M. R.; Zhang, Y.; Bogdan, M.; Smith, B. D.; Lozano, G.; Flynn, D. L.; snyder, e.; Kinsey, C. G.
10.1101/2024.02.06.579200 — cancer biology — Posted on 2024-02-08
3368 Single-molecule evidence of Entropic Pulling by Hsp70 chaperones
Rukes, V.; Rebeaud, M. E.; Perrin, L.; De Los Rios, P.; Cao, C.
10.1101/2024.02.06.579217 — biophysics — Posted on 2024-02-08
3369 MS-DIAL 5 multimodal mass spectrometry data mining unveils lipidome complexities
Takeda, H.; Matsuzawa, Y.; Takeuchi, M.; Takahashi, M.; Nishida, K.; Harayama, T.; Todoroki, Y.; Shimizu, K.; Sakamoto, N.; Oka, T.; Maekawa, M.; Chung, M. H.; Kurizaki, Y.; Kiuchi, S.; Tokiyoshi, K.; Buyantogtokh, B.; Kurata, M.; Kvasnicka, A.; Takeda, U.; Uchino, H.; Hasegawa, M.; Miyamoto, J.; Tanabe, K.; Takeda, S.; Mori, T.; Kumakubo, R.; Tanaka, T.; Yoshino, T.; Arita, M.; Tsugawa, H.
10.1101/2024.02.07.579267 — bioinformatics — Posted on 2024-02-08
3370 S-nitrosylation of EZH2 at C329 and C700 interplay with PRC2 complex assembly, methyltransferase activity, and EZH2 stability to regulate endothelial functions
Sakhuja, A.; Katakia, Y. T.; Tripathi, S. M.; Bhattacharya, R.; Thakkar, N. P.; Ramakrishnan, S.; Chakraborty, S.; Thakar, S.; Sundriyal, S.; Chowdhury, S.; Majumder, S.
10.1101/2024.02.06.579117 — cell biology — Posted on 2024-02-08
3372 Crypt and Villus Enterochromaffin Cells are Distinct Stress Sensors in the Gut
Touhara, K. K.; Rossen, N. D.; Deng, F.; Chu, T.; Cil, O.; Li, Y.; Julius, D.
10.1101/2024.02.06.579180 — physiology — Posted on 2024-02-08
3373 Traditional uses and pharmacological activities of Tetracera alnifolia (Wild) Drake
Camara, A. K.; Balde, E. S.; Diallo, M. S. T.; Camara, M. K.; Bah, T. V.; Conde, M.; Soumah, A.; Tietjen, I.; Balde, A. M.
10.1101/2024.02.07.579282 — pharmacology and toxicology — Posted on 2024-02-08
3375 Identification of B cell subsets based on antigen receptor sequences using deep learning
Lee, H.; Shin, K.; Lee, Y.; Lee, S.; Lee, S.; Lee, E.; Kim, S. W.; Shin, H. Y.; Kim, J. H.; Chung, J.; Kwon, S.
10.1101/2024.02.06.579098 — bioinformatics — Posted on 2024-02-08
3377 TumFlow: An AI Model for Predicting New Anticancer Molecules
Rigoni, D.; Yaddehige, S.; Bianchi, N.; Sperduti, A.; Moro, S.; Taccioli, C.
10.1101/2024.02.06.579053 — bioinformatics — Posted on 2024-02-08
3381 Longitudinal Fragility phenotyping predicts lifespan and age-associated morbidity in C57BL/6 and Diversity Outbred mice
Luciano, A.; Robinson, L.; Garland, G.; Lyons, B.; Korstanje, R.; Di Francesco, A.; Churchill, G. A.
10.1101/2024.02.06.579096 — bioinformatics — Posted on 2024-02-08
3383 Exploring muscle recruitment by Bayesian methods during motion
Amankwah, M.; Bersani, A.; Calvetti, D.; Davico, G.; Somersalo, E.; Viceconti, M.
10.1101/2024.02.06.579136 — bioengineering — Posted on 2024-02-08
3384 Homologous recombination deficiency and tumor suppressor heterozygosity mediate resistance to front-line therapy in breast cancer
Safonov, A.; Marra, A.; Bandlamudi, C.; O'Leary, B.; Wubbenhorst, B.; Moiso, E.; Lee, M.; Donoghue, M.; An, J. A.-R.; Will, M.; Pareka, F.; Ahmed, M.; Nizialek, E.; Lukashchuk, N.; Sofianopoulou, E.; Liu, Y.; Huang, X.; Schultz, N.; Berger, M.; Scaltriti, M.; Reis-Filho, J. S.; Li, B. T.; Offit, K.; Norton, L.; Solit, D. B.; Shah, S.; Maxwell, K. N.; Couch, F.; Nathanson, K. L.; Robson, M. E.; Turner, N. C.; Chandarlapaty, S.; Razavi, P.
10.1101/2024.02.05.578934 — genomics — Posted on 2024-02-08
3385 Whole Genome Sequencing of DENV-2 isolated from Aedes aegypti mosquitoes in Esmeraldas, Ecuador. Genomic epidemiology of genotype III Southern Asian-American in the country.
Carrazco-Montalvo, A.; Gutierrez-Pallo, D.; Arevalo, V.; Ponce, P.; Rodriguez-Polit, C.; Alarcon, D.; Echeverria-Garces, G.; Coloma, J.; Nipaz, V.; Cevallos, V.
10.1101/2024.02.06.579255 — genomics — Posted on 2024-02-08
3387 Screening and assessment of functional variants by regulatory features from epigenomic data in livestock species
Ma, R.; Kuang, R.; Zhang, J.; Xu, Y.; Han, Z.; Hu, M.; Wang, D.; Luan, Y.; Fu, Y.; Zhang, Y.; Li, X.; Zhu, M.; Xiang, T.; Zhao, S.; Zhao, Y.
10.1101/2024.02.06.578787 — genomics — Posted on 2024-02-08
3388 Prelude to Malignancy: A Gene Expression Signature in Normal Mammary Gland from Breast Cancer Patients Suggests Pre-tumorous Alterations and Is Associated with Adverse Outcomes
Andreou, M.; Jakalski, M.; Duzowska, K.; Filipowicz, N.; Kostecka, A.; Davies, H.; Horbacz, M.; Lawrynowicz, U.; Chojnowska, K.; Bruhn-Olszewska, B.; Jankau, J.; Srutek, E.; Las-Jankowska, M.; Bala, D.; Hoffman, J.; Hartman, J.; Peksa, R.; Skokowski, J.; Jankowski, M.; Szylberg, L.; Zegarski, W.; Nowikiewicz, M.; Nowikiewicz, T.; Dumanski, J. P.; Mieczkowski, J.; Piotrowski, A.
10.1101/2024.02.07.579074 — genomics — Posted on 2024-02-08
3393 Disentangling the age-dependent causal pathways affecting multiple paternity in house sparrows
Soraker, J.; Ranke, P. S.; Wright, J.; Ringsby, T. H.; Saether, B.-E.; Jensen, H.; Araya-Ajoy, Y.
10.1101/2024.02.05.579001 — ecology — Posted on 2024-02-08
3394 Old, deciduous stands support both high biodiversity and carbon storage in German forests
Springer, K.; Manning, P.; Boesing, A. L.; Ammer, C.; Fiore-Donno, A. M.; Fischer, M.; Goldmann, K.; Le Provost, G.; Overmann, J.; Ruess, L.; Schoening, I.; Seibold, S.; Sikorski, J.; Neyret, M.
10.1101/2024.02.06.578731 — ecology — Posted on 2024-02-08
3397 Disentangling competitive and cooperative components of the interactions between microbial species
Ansari, A. F.; Sambamoorthy, G.; Alexander, T. C.; Reddy, Y. B. S.; Raut, J.; Dixit, N. M.
10.1101/2024.02.06.579244 — ecology — Posted on 2024-02-08
3399 Progressive cell fate specification in morphallactic regeneration
Nuninger, C.; Papasaikas, P.; Ferralli, J.; Smallwood, S.; Tsiairis, C. D.
10.1101/2024.02.08.579449 — developmental biology — Posted on 2024-02-08
3400 Optogenetic control of pheromone gradients reveals functional limits of mating behavior in budding yeast
Banderas, A.; Hofmann, M.; Cordier, C.; Le Bec, M.; Elizondo, C.; Chiron, L.; Pouzet, S.; Scolari, V.; Hersen, P.
10.1101/2024.02.06.578657 — cell biology — Posted on 2024-02-08
3402 Gentle rhodamines for live-cell fluorescence microscopy
Liu, T.; Kompa, J.; Ling, J.; Lardon, N.; Zhang, Y.; Chen, J.; Reymond, L.; Chen, P.; Tran, M.; Yang, Z.; Zhang, H.; Liu, Y.; Pitsch, S.; Zou, P.; Wang, L.; Johnsson, K.; Chen, Z.
10.1101/2024.02.06.579089 — cell biology — Posted on 2024-02-08
3403 PRMT5 deficiency disturbs Nur77 methylation to inhibit endometrial stromal cell differentiation in recurrent implantation failure
Cao, Z.; Wang, X.; Liu, Y.; Tang, X.; Wu, M.; Zhen, X.; Kang, N.; Ding, L.; Sun, J.; Cai, X.; Sun, H.; Yan, G.; JIANG, R.
10.1101/2024.02.06.579055 — cell biology — Posted on 2024-02-08
3406 Spatial transcriptomics elucidates medulla niche supporting germinal center response in myasthenia gravis thymoma
Yasumizu, Y.; Kinoshita, M.; Zhang, M. J.; Motooka, D.; Suzuki, K.; Okuzaki, D.; Nojima, S.; Funaki, S.; Shintani, Y.; Ohkura, N.; MOrii, E.; Okuno, T.; Mochizuki, H.
10.1101/2024.02.05.579042 — immunology — Posted on 2024-02-08
3411 A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Saini, V. M.; Oner, E.; Ward, M.; Hurley, S.; Henderson, B. D.; Lewis, F.; Finn, S. P.; O'Leary, J.; O'Toole, S.; O'Driscoll, L.; Gately, K.
10.1101/2024.02.05.578972 — cancer biology — Posted on 2024-02-08
3412 Focal Deletions of a Promoter Tether Activate the IRX3 Oncogene in T Cell Acute Lymphoblastic Leukemia
Rahman, S.; Bloye, G.; Farah, N.; Demeulemeester, J.; Costa, J. R.; O'Connor, D.; Pocock, R.; Turna, A.; Wang, L.; Lee, S.; Fielding, A. K.; Roels, J.; Jaksik, R.; Dawidowska, M.; Vlierberghe, P. V.; Hadjur, S.; Hughes, J. R.; Davies, J. O. J.; Gutierrez, A.; Kelliher, M. A.; Loo, P. V.; Dawson, M. A.; Mansour, M. R.
10.1101/2024.02.06.579027 — cancer biology — Posted on 2024-02-08
3414 Spatial architecture of CD8+ T cells and DC subsets is critical for the response to immune checkpoint inhibitors in melanoma
Gobbini, E.; Hubert, M.; Doffin, A.-C.; Eberhardt, A.; Hermet, L.; Li, D.; Duplouye, P.; Barrin, S.; Berthet, J.; Benboubker, V.; Grimont, M.; Sakref, C.; Perrot, J.; Tondeur, G.; Harou, O.; Lopez, J.; Dubois, B.; Dalle, S.; Caux, C.; Caramel, J.; Valladeau-Guilemond, J.
10.1101/2024.02.06.579128 — cancer biology — Posted on 2024-02-08
3419 Decoding cell identity with multi-scale explainable deep learning
Zhu, J.; Zhang, Z.; Xiang, Y.; Xie, B.; Dong, X.; Xie, L.; Zhou, P.; Yao, R.; Wang, X.; Li, Y.; He, F.; Zhu, W.; Zhang, Z.; Chang, C.
10.1101/2024.02.05.578922 — bioinformatics — Posted on 2024-02-08
3421 Quantifying the seed sensitivity of cancer subclonal reconstruction algorithms
Steinberg, P. L.; Liu, L. Y.; Neiman-Golden, A.; Patel, Y.; Boutros, P. C.
10.1101/2024.02.05.579021 — bioinformatics — Posted on 2024-02-08
3426 Far-red and sensitive sensor for monitoring real-time H2O2 dynamics with subcellular resolution and inmulti-parametric imaging applications.
Lee, J. D.; Nguyen, A.; Jin, Z. R.; Moghadasi, A.; Gibbs, C. E.; Wait, S. J.; Evitts, K. M.; Asencio, A.; Bremner, S. B.; Zuniga, S.; Chavan, V.; Williams, A.; Smith, N.; Regnier, M.; Young, J. E.; Mack, D. L.; Nance, E.; Boyle, P. M.; Berndt, A.
10.1101/2024.02.06.579232 — bioengineering — Posted on 2024-02-08
3428 Repurposing CRISPR-Cas13 systems for robust mRNA trans-splicing
Fiflis, D. N.; Rey, N.; Lavanya, H. V.; Sewell, B.; Mitchell-Dick, A.; Milo, S.; Clements, K.; Benkert, A.; Rosales, A.; Fergione, S.; Asokan, A.
10.1101/2024.02.06.579165 — bioengineering — Posted on 2024-02-08
3432 Neural basis of self-control
Lee, K. E.; Elsey, J.; Hwang, J.; Emeric, E.; Stuphorn, V.
10.1101/2024.02.07.578652 — neuroscience — Posted on 2024-02-08
3437 Generation of surrogate brain maps preserving spatial autocorrelation through random rotation of geometric eigenmodes
Koussis, N. C.; Pang, J. C.; Jeganathan, J.; Paton, B.; Fornito, A.; Robinson, P. A.; Misic, B.; Breakspear, M.
10.1101/2024.02.07.579070 — neuroscience — Posted on 2024-02-08
3438 Bayesian Modelling Approaches for Breath-Hold Induced Cerebrovascular Reactivity
Hayes, G.; Bulte, D. P.; Moia, S.; Craig, M.; Chappell, M.; Urunuela, E.; Sparks, S.; Caballero Gaudes, C.; Pinto, J.
10.1101/2024.02.06.579134 — neuroscience — Posted on 2024-02-08
3440 The genetic landscape, gene flow and adaptation in Ladakh highlanders of trans-Himalayas
Kumar, L.; Rajpal, R.; Ahlawat, B.; Pasupuleti, N.; Konar, S.; Dwivedi, A.; Kumar, S.; Spalzin, S.; Rabyang, S.; Thangaraj, K.; Rai, N.
10.1101/2024.02.05.579041 — genetics — Posted on 2024-02-08
3445 Compressive stress drives morphogenetic apoptosis
Merle, T.; Cazales, M.; Bouzignac, R.; Ronsin, B.; Rouviere, C.; Suzanne, M.
10.1101/2024.02.08.579454 — developmental biology — Posted on 2024-02-08
3446 Decoding morphogen patterning of human neural organoids with a multiplexed single-cell transcriptomic screen
Sanchis-Calleja, F.; Jain, A.; He, Z.; Okamoto, R.; Rusimbi, C.; Rifes, P.; Rathore, G. S.; Santel, M.; Janssens, J.; Seimiya, M.; Fleck, J. S.; Kirkeby, A.; Camp, J. G.; Treutlein, B.
10.1101/2024.02.08.579413 — developmental biology — Posted on 2024-02-08
3447 Altered inflammatory state and mitochondrial function identified by transcriptomics in paediatric congenital heart patients prior to surgical repair
Bartoli-Leonard, F.; Harris, A. G.; Saunders, K.; Madden, J.; Cherrington, C.; Sheehan, K.; Baquedano, M.; Parolari, G.; Bamber, A.; Caputo, M.
10.1101/2024.02.05.577755 — immunology — Posted on 2024-02-08
3448 Multi-site Ultrashort Echo Time 3D Phosphorous MRSI repeatability using novel Rosette Trajectory (PETALUTE)
Alcicek, S.; Craig-Craven, A. R.; Shen, X.; Chiew, M.; Ozen, A.; Sawiak, S.; Pilatus, U.; emir, u.
10.1101/2024.02.07.579294 — neuroscience — Posted on 2024-02-08
3449 An Atlas of Brain-Bone Sympathetic Neural Circuits
Ryu, V.; Gumerova, A. A.; Witztum, R.; Korkmaz, F.; Kannangara, H.; Moldavski, O.; Barak, O.; Lizneva, D.; Goosens, K. A.; Stanley, S.; Kim, S.-M.; Yuen, T.; Zaidi, M.
10.1101/2024.02.07.579382 — neuroscience — Posted on 2024-02-08
3451 Dynamic Lateralization in Contralateral-Projecting Corticospinal Neurons During Motor Learning
Han, J.; Wang, R.; Wang, M.; Yu, Z.; Zhu, L.; Zhang, J.; Zhu, J.; Zhang, S.; Xi, W.; Wu, H.
10.1101/2024.02.08.579456 — neuroscience — Posted on 2024-02-08
3452 Unlocking the secrets of kangaroo locomotor energetics: Postural adaptations underpin increased tendon stress in hopping kangaroos
Thornton, L.; Dick, T.; Hutchinson, J. R.; Lichtwark, G. A.; McGowan, C. P.; Rubenson, J.; Wiktorowicz-Conroy, A.; Clemente, C.
10.1101/2024.02.05.578950 — zoology — Posted on 2024-02-08
3454 Spatial transcriptomic profiling of human retinoblastoma
Wang, L.; Hung, S.; Urrutia-Cabrera, D.; Kong, R. C. K.; Staffieri, S.; Ludlow, L. E.; Lau, X.; Wang, P.-Y.; Hewitt, A. W.; Wong, R. C. B.
10.1101/2024.02.05.578886 — systems biology — Posted on 2024-02-08
3455 A foundational atlas of autism protein interactions reveals molecular convergence
Wang, B.; Vartak, R.; Zaltsman, Y.; Naing, Z. Z. C.; Hennick, K. M.; Polacco, B. J.; Bashir, A.; Eckhardt, M.; Bouhaddou, M.; Xu, J.; Sun, N.; Lasser, M.; Zhou, Y.; Guiley, K. Z.; Chan, U.; Kaye, J. A.; Khare, P.; Drake, S.; Drury, V.; Burke, D. F.; Gonzalez, S.; Alkhairy, S.; Morris, M.; Baum, T.; Krasnoff, R.; Wang, S.; Pham, P.; Arbalaez, J.; Pratt, D.; Chag, S.; Rolland, T.; Bourgeron, T.; Finkbeiner, S.; Bandyopadhay, S.; Ideker, T.; Beltrao, P.; Willsey, H. R.; Obernier, K.; Nowakowski, T. J.; Huttenhain, R.; State, M. W.; Willsey, A. J.; Krogan, N. J.
10.1101/2023.12.03.569805 — systems biology — Posted on 2024-02-08
3457 Thermogenetics for cardiac pacing
Balatskiy, A. V.; Nesterenko, A. M.; Lanin, A. A.; Ovechkina, V. S.; Sabinin, S. S.; Fetisova, E. S.; Moshchenko, A. A.; Jappy, D.; Sokolov, R. A.; Biglova, D. Z.; Solius, G. M.; Solius, E. M.; Korolev, S. V.; Podgorny, O. V.; Kelmanson, I. V.; Rozov, A. V.; Fedotov, A. B.; Bruegmann, T.; Zheltikov, A. M.; Mozhaev, A. A.; Belousov, V. V.
10.1101/2024.01.02.573885 — synthetic biology — Posted on 2024-02-08
3459 Simulation-Driven Design of Stabilized SARS-CoV-2 Spike S2 Immunogens
Nuqui, X.; Casalino, L.; Zhou, L.; Shehata, M.; Wang, A.; Tse, A. L.; Ojha, A.; Kearns, F. L.; Rosenfeld, M. A.; Miller, E. H.; Acreman, C. M.; Ahn, S.-H.; Chandran, K.; McLellan, J. S.; Amaro, R. E.
10.1101/2023.10.24.563841 — biophysics — Posted on 2024-02-08
3463 Climate change, age acceleration, and the erosion of fitness in polar bears
Newediuk, L.; Richardson, E. S.; Biddlecombe, B. A.; Kassim, H.; Kathan, L.; Lunn, N.; Rivkin, L. R.; Salama, O. E.; Schmidt, C.; Jones, M. J.; Garroway, C. J.
10.1101/2024.01.05.574416 — ecology — Posted on 2024-02-08
3464 REL2 overexpression in the Anopheles gambiae midgut causes major transcriptional changes but fails to induce an immune response
Hoermann, A.; Capriotti, P.; Del Corsano, G.; Inghilterra, M. G.; Habtewold, T.; Cai, J. A.; Saini, G. S.; Nguyen, H.; Windbichler, N.; Christophides, G. K.
10.1101/2024.02.05.578852 — immunology — Posted on 2024-02-08
3466 Differential genetic expression within reward-specific ensembles in mice
Litif, C. G.; Flom, L. T.; Sandum, K. L.; Hodgins, S. L.; Vaccaro, L.; Stitzel, J. A.; Blouin, N. A.; Mannino, M. C.; Gigley, J. P.; Schoborg, T.; Bobadilla, A.-C.
10.1101/2023.11.02.565378 — neuroscience — Posted on 2024-02-08
3467 Homeostatic regulation of REM sleep by the preoptic area of the hypothalamus
Maurer, J. J.; Lin, A.; Jin, X.; Hong, J.; Sathi, N.; Cardis, R.; Osorio-Forero, A.; Lüthi, A.; Weber, F.; Chung, S.
10.1101/2023.08.22.554341 — neuroscience — Posted on 2024-02-08
3468 Neurotensin-Neurotensin Receptor 2 signaling in adipocytes regulates food intake through ceramide metabolism
Fu, W.; Yang, Y.; Zhang, Z.; So, J.; Roh, H.-C.; Liu, T.; Xu, M.; Zheng, Y.; Huang, H.; Li, J.
10.1101/2024.02.07.579397 — physiology — Posted on 2024-02-08
3469 The molecular basis of the anticancer effect of statins
Buccioli, G.; Testa, C.; Jacchetti, E.; Pinoli, P.; Carelli, S.; Ceri, S.; Raimondi, M. T.
10.1101/2024.02.05.578869 — cancer biology — Posted on 2024-02-08
3470 Hydrodynamic Radii of Intrinsically Disordered Proteins: Fast Prediction by Minimum Dissipation Approximation and Experimental Validation
Waszkiewicz, R.; Michas, A.; Bialobrzewski, M. K.; Klepka, B. P.; Cieplak-Rotowska, M. K.; Staszalek, Z.; Cichocki, B.; Lisicki, M.; Szymczak, P.; Niedzwiecka, A.
10.1101/2024.02.05.578612 — biophysics — Posted on 2024-02-08
3474 Fast and accurate modeling and design of antibody-antigen complex using tFold
Wu, F.; Zhao, Y.; Wu, J.; Jiang, B.; He, B.; Huang, L.; Qin, C.; Yang, F.; Huang, N.; Xiao, Y.; Wang, R.; Jia, H.; Rong, Y.; Liu, Y.; Lai, H.; Xu, T.; Liu, W.; Zhao, P.; Yao, J.
10.1101/2024.02.05.578892 — bioinformatics — Posted on 2024-02-08
3477 Novel multi-omics deconfounding variational autoencoders can obtain meaningful disease subtyping
Li, Z.; Katz, S.; Martins dos Santos, V. A. P.; Fardo, D.; Claes, P.; Saccenti, E.; Van Steen, K.; Roshchupkin, G. V.
10.1101/2024.02.05.578873 — genomics — Posted on 2024-02-08
3479 Biotic interactions promote local adaptation to soil in plants
Dorey, T.; Frachon, L.; Rieseberg, L. H.; Kreiner, J.; Schiestl, F.
10.1101/2024.02.05.578857 — evolutionary biology — Posted on 2024-02-08
3481 The glucocorticoid receptor elicited proliferative response in human erythropoiesis is BCL11A-dependent
Mazzarini, M.; Cherone, J.; Nguyen, T.; Martelli, F.; Varricchio, L.; Funnell, A. P. W.; Papayannopoulou, T.; Migliaccio, A. R.
10.1101/2024.02.05.577972 — cell biology — Posted on 2024-02-08
3487 Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function
Thomas, R. M.; Pahl, M. C.; Wang, L.; Grant, S. F.; Hancock, W. W.; WELLS, A. D.
10.1101/2023.05.23.541951 — immunology — Posted on 2024-02-08
3488 Corticostriatal responses to social reward are linked to reward sensitivity and subclinical substance use
Wyngaarden, J. B.; Johnston, C. R.; Sazhin, D.; Dennison, J. B.; Zaff, O.; Fareri, D.; McCloskey, M.; Alloy, L. B.; Smith, D. V.; Jarcho, J. M.
10.1101/2023.01.17.524305 — neuroscience — Posted on 2024-02-08
3489 Neuroticism/negative emotionality is associated with increased reactivity to uncertain threat in the bed nucleus of the stria terminalis, not the amygdala
Grogans, S. E.; Hur, J.; Barstead, M. G.; Anderson, A. S.; Islam, S.; Kim, H. C.; Kuhn, M.; Tillman, R. M.; Fox, A. S.; Smith, J. F.; DeYoung, K. A.; Shackman, A. J.
10.1101/2023.02.09.527767 — neuroscience — Posted on 2024-02-08
3491 Disrupted cardiac bioenergetics linked to oxidized mitochondrial creatine kinase are rescued by the mitochondrial-targeting peptide SBT-20 in the D2.mdx model of Duchenne muscular dystrophy
Perry, C. G. R.; Hughes, M. C.; Ramos, S. V.; Brahmbhatt, A.; Turnbull, P. C.; Polidovitch, N.; Garibotti, M. C.; Schlattner, U.; Hawke, T. J.; Simpson, J. A.; Backx, P. H.
10.1101/2024.02.04.578832 — physiology — Posted on 2024-02-08
3492 SREBP-dependent regulation of lipid homeostasis is required for progression and growth of pancreatic ductal adenocarcinoma
Ishida, C. T.; Myers, S. L.; Shao, W.; McGuire, M. R.; Liu, C.; Kubota, C. S.; Ewachiw, T. E.; Mukhopadhyay, D.; Ke, S.; Wang, H.; Rasheed, Z. A.; Anders, R. A.; Espenshade, P. J.
10.1101/2024.02.04.578802 — cancer biology — Posted on 2024-02-08
3493 Broad de-regulated U2AF1 splicing is prognostic and augments leukemic transformation via protein arginine methyltransferase activation
Venkatasubramanian, M.; Schwartz, L.; Ramachandra, N.; Bennett, J.; Subramanian, K. R.; Gordon-Mitchell, S.; Fromowitz, A.; Pradhan, K.; Shechter, D.; Sahu, S.; Heiser, D.; Scherle, P.; Chen, X.; Chetal, C.; Kulkarni, A.; Myers, K. C.; Weirauch, M. T.; Grimes, H. L.; Starczynowski, D. T.; Verma, A.; Salomonis, N. G.
10.1101/2024.02.04.578798 — cancer biology — Posted on 2024-02-08
3495 Defining the conformational states that enable transglutaminase 2 to promote cancer cell survival versus cell death
Aplin, C.; Zielinski, K. A.; Pabit, S.; Ogunribido, D.; Katt, W. P.; Pollack, L.; Cerione, R. A.; Milano, S. K.
10.1101/2024.02.04.578794 — biophysics — Posted on 2024-02-08
3498 Laminin-defined Mechanical Status Modulates Retinal Pigment Epithelium Functionality
Kozyrina, A. N.; Piskova, T.; Semeraro, F.; Doolaar, I.; Prapty, T.; Haraszti, T.; Hubert, M.; Windoffer, R.; Leube, R. E.; Smith, A.-S.; Di Russo, J.
10.1101/2023.02.24.529913 — biophysics — Posted on 2024-02-08
3503 A self-adaptive and versatile tool for eliminating multiple undesirable variations from transcriptome
Zhang, M.; Yan, L.; Wang, X.; Yuan, Y.; Zou, S.; Yao, S.; Wang, X.; Xu, T.; Chen, B.; Yang, D.
10.1101/2024.02.04.578839 — bioinformatics — Posted on 2024-02-08
3504 Finding and Following: A deep learning-based pipeline for tracking platelets during thrombus formation in vivo and ex vivo
McGovern, A. S.; Larsson, P.; Tarlac, V.; Setiabakti, N.; Shabani Mashcool, L.; Hamilton, J. R.; Boknäs, N.; Nunez-Iglesias, J.
10.1101/2023.10.02.560609 — bioinformatics — Posted on 2024-02-08
3505 Arktos: a simple tool for the design of polyhedral DNA nanostructures
Balaji, H.; Kolipakala, R. S.; Samprathi, A. H.; Pradeep, P.; Nagarajan, D.
10.1101/2024.02.07.576791 — bioinformatics — Posted on 2024-02-08
3506 Large-scale characterization of drug mechanism of action using proteome-wide thermal shift assays
Van Vranken, J. G.; Li, J.; Mintseris, J.; Gadzuk-Shea, M.; Gygi, S. P.; Schweppe, D.
10.1101/2024.01.26.577428 — biochemistry — Posted on 2024-02-08
3510 Perceptual biases, camouflage patterns, and the origin of sexual signals
Hejja-Brichard, Y.; Raymond, M.; Cuthill, I. C.; Mendelson, T. C.; Renoult, J. P.
10.1101/2023.09.27.559753 — evolutionary biology — Posted on 2024-02-08
3514 Photoprotective melanin is maintained within keratinocytes in a storage lysosome
Neto, M. V.; Hall, M. J.; Charneca, J.; Escrevente, C.; Seabra, M. C.; Barral, D. C.
10.1101/2024.02.05.578910 — cell biology — Posted on 2024-02-08
3515 GSK3 inhibition ameliorates the abnormal contractility of Newfoundland ACM patient iPSC-cardiomyocytes
Noort, R. J.; Salman, W.; Porter, Z. G.; Sadighian, H.; Fuchs, C.; Braun, U.; Pace, D.; Belbin, T.; Hodgkinson, K.; Esseltine, J. L.
10.1101/2024.02.06.579108 — cell biology — Posted on 2024-02-08
3516 Single-cell trait diversity explains niche and fitness differences in aquatic microbial communities
Fontana, S.; Schmitz, D. A.; Daniels, M.; Danza, F.; Röösli, T.; Bruderer, H.; Walser, J.-C.; Dekaezemacker, J.; Escrig, S.; Meibom, A.; Pomati, F.; Schreiber, F.
10.1101/2024.02.07.579265 — microbiology — Posted on 2024-02-08
3517 Aminoglycoside tolerance in Vibrio cholerae engages translational reprogramming associated to queuosine tRNA modification
Fruchard, L.; Babosan, A.; Carvalho, A.; Lang, M.; Li, B.; Duchateau, M.; Giai Gianetto, Q.; Matondo, M.; Bonhomme, F.; Hatin, I.; Arbes, H.; Fabret, C.; Sanchez, G.; MArchand, V.; Motorine, Y.; NAMY, O.; de Crecy-Lagard, V.; Mazel, D.; Baharoglu, Z.
10.1101/2022.09.26.509455 — microbiology — Posted on 2024-02-08
3518 Niche formation and metabolic interactions result in stable diversity in a spatially structured cyanobacterial community
Duxbury, S. J. N.; Raguideau, S.; Cremin, K.; Rosko, J.; Coates, M.; Randall, K.; Chen, J.; Quince, C.; soyer, o. s.
10.1101/2022.12.13.520286 — microbiology — Posted on 2024-02-08
3519 Quantifying the daily harvest of fermentation products from the human gut microbiota
Arnoldini, M.; Sharma, R.; Moresi, C.; Chure, G.; Chabbey, J.; Slack, E.; Cremer, J.
10.1101/2024.01.05.573977 — microbiology — Posted on 2024-02-08
3520 Endosomal LRBA regulates the endo-lysosomal pathway
Szentgyoergyi, V.; Lueck, L. M.; Overwijn, D.; Zoeller, N. N.; Hondele, M.; Spang, A.; Bakhtiar, S.
10.1101/2024.02.07.579084 — immunology — Posted on 2024-02-08
3522 copepodTCR: Identification of Antigen-Specific T Cell Receptors with combinatorial peptide pooling
Kovaleva, V. A.; Pattinson, D. J.; Barton, C.; Chapin, S. R.; Minervina, A. A.; Richards, K. A.; Sant, A. J.; Thomas, P. G.; Pogorelyy, M. V.; Meyer, H. V.
10.1101/2023.11.28.569052 — immunology — Posted on 2024-02-08
3523 BATMAN: Improved T cell receptor cross-reactivity prediction benchmarked on a comprehensive mutational scan database
Banerjee, A.; Pattinson, D. J.; Wincek, C. L.; Bunk, P.; Chapin, S. R.; Navlakha, S.; Meyer, H. V.
10.1101/2024.01.22.576714 — immunology — Posted on 2024-02-08
3524 A Synergistic Workspace for Human Consciousness Revealed by Integrated Information Decomposition
Luppi, A. I.; Mediano, P. A. M.; Rosas, F. E.; Allanson, J.; Pickard, J. D.; Carhart-Harris, R. L.; Williams, G. B.; Craig, M. M.; Finoia, P.; Owen, A. M.; Naci, L.; Menon, D. K.; Bor, D.; Stamatakis, E. A.
10.1101/2020.11.25.398081 — neuroscience — Posted on 2024-02-08
3525 Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy
Abreo, T. J.; Thompson, E. C.; Madabushi, A.; Soh, H.; Varghese, N.; Vanoye, C. G.; Springer, K.; Park, K. L.; Johnson, J.; Sims, S.; Ji, Z.; Chavez, A. G.; Jankovic, M. J.; Habte, B.; Zuberi, A. R.; Lutz, C. M.; Wang, Z.; Krishnan, V.; Dudler, L.; Einsele-Scholz, S.; Noebels, J. L.; George, A. L.; Maheshwari, A.; Tzingounis, A.; Cooper, E.
10.1101/2024.01.04.574177 — neuroscience — Posted on 2024-02-08
3527 Dopamine and DBS accelerate the neural dynamics of volitional action in Parkinson's disease
Köhler, R. M.; Binns, T. S.; Merk, T.; Zhu, G.; Yin, Z.; Zhao, B.; Chikermane, M.; Vanhoecke, J.; Busch, J. L.; Habets, J. G. V.; Faust, K.; Schneider, G.-H.; Cavallo, A.; Haufe, S.; Zhang, J.; Kühn, A. A.; Haynes, J.-D.; Neumann, W.-J.
10.1101/2023.10.30.564700 — neuroscience — Posted on 2024-02-08
3529 Prior probability cues bias sensory encoding with increasing task exposure
Walsh, K.; McGovern, D. P.; Dully, J.; Kelly, S. P.; O'Connell, R. G.
10.1101/2023.07.15.549123 — neuroscience — Posted on 2024-02-08
3530 Reconfigurations of cortical manifold structure during reward-based motor learning
Nick, Q.; Gale, D. J.; Areshenkoff, C.; De Brouwer, A. J.; Nashed, J. Y.; Wammes, J.; Zhu, T.; Flanagan, J. R.; Smallwood, J.; Gallivan, J.
10.1101/2023.07.05.547880 — neuroscience — Posted on 2024-02-08
3531 CNTN4 modulates neural elongation through interplay with APP
Bamford, R. A.; Zuko, A.; Sprengers, J. J.; Post, H.; Taggenbrock, R. L. R. E.; Mehr, A.; Jones, O. J. R.; Kudzinskas, A.; Gandawijaya, J.; Eve, M.; Muller, U. C.; Kas, M. J.; Burbach, J. P. H.; Oguro-Ando, A.
10.1101/2023.08.25.554833 — neuroscience — Posted on 2024-02-08
3538 Distinguishable topological properties of functional genome networks in HIV-1 reservoirs
Wisniewski, J.; Wiecek, K.; Ali, H.; Pyrc, K.; Kula-Pacurar, A.; Wagner, M.; CHEN, H.-C.
10.1101/2024.02.05.578936 — genomics — Posted on 2024-02-08
3540 Bacterial ecology and evolution converge on seasonal and decadal scales
Rohwer, R. R.; Kirkpatrick, M.; Garcia, S. L.; Kellom, M.; McMahon, K. D.; Baker, B. J.
10.1101/2024.02.06.579087 — evolutionary biology — Posted on 2024-02-08
3542 Huntingtin is an RNA-binding protein and participates in NEAT1-mediated paraspeckles
Yadav, M.; Harding, R. J.; Li, T.; Xu, X.; Gall-Duncan, T.; Khan, M.; Ferrari Bardile, C.; Sequiera, G. L.; Duan, S.; Chandrasekaran, R.; Pan, A.; Bu, J.; Yamazaki, T.; Hirose, T.; Prinos, P.; Tippett, L.; Turner, C.; Curtis, M. A.; Faull, R. L. M.; Pouladi, M. A.; Pearson, C. E.; He, H. H.; Arrowsmith, C. H.
10.1101/2024.02.07.579162 — cell biology — Posted on 2024-02-08
3544 In a Canine Model of Septic Shock, Cardiomyopathy Occurs Independent of Catecholamine Surges and Cardiac Microvascular Ischemia
Ford, V. J.; Applefeld, W. N.; Wang, J.; Sun, J.; Solomon, S. B.; Klein, H. G.; Feng, J.; Lertora, J.; TORABI-PARIZI, P.; Danner, R. L.; Solomon, M. A.; Chen, M. Y.; Natanson, C.
10.1101/2024.02.05.578927 — physiology — Posted on 2024-02-08
3545 ASPYRE-Lung: Validation of a simple, fast, robust and novel method for multi-variant genomic analysis of actionable NSCLC variants in tissue
Evans, R. T.; Gillon-Zhang, E.; Brown, J. N.; Knudsen, K. E.; King, C.; Green, A. S.; Silva, A.-L.; Mordaka, J. M.; Palmer, R. N.; Tomassini, A.; Collazos, A.; Xyrafaki, C.; Turner, I.; Ho, C. H.; Nugent, D.; Jose, J.; Andreazza, S.; von Bargen, K.; Gray, E. R.; Stolarek-Januszkiewicz, M.; Cooke, A.; Reddi, H.; Balmforth, B.; Osborne, R. J.
10.1101/2024.02.07.579135 — cancer biology — Posted on 2024-02-08
3554 Evolutionary analysis of genome-specific duplications in flatworm genomes
Langleib, M.; Calvelo, J.; Costabile, A.; Castillo, E.; Tort, J. F.; Hoffmann, F. G.; Protasio, A. V.; Koziol, U.; Iriarte, A.
10.1101/2024.02.05.578899 — evolutionary biology — Posted on 2024-02-08
3556 Regulatory divergences in dosage compensation cause hybrid male inviability in Caenorhabditis
Li, Y.; Gao, Y.; Ma, J.; Gao, Y.; Zhou, W.; Zhang, H.; Shao, W.; Liu, Z.; Zhao, Z.; Liu, X.
10.1101/2024.02.06.577000 — evolutionary biology — Posted on 2024-02-08
3557 Arktos: a simple tool for the design of polyhedral 1DNA nanostructures
Balaji, H.; Kolipakala, R. S.; Samprathi, A. H.; Pradeep, P.; Nagarajan, D.
10.1101/2024.02.07.576791 — bioinformatics — Posted on 2024-02-08
3563 Long-term disruption of glucose homeostasis in a rodent model of preterm birth.
Diao, S.; Guenoun, D.; Chen, S.-P.; CRUCIANI-GUGLIELMACCI, C.; Pansiot, J.; Laforge, M.; Raho, I.; Faivre, V.; Degos, V.; Gressens, P.; Nadjar, A.; Van Steenwinckel, J.; Adle-Biasette, H.; Magnan, C.; Jacquens, A.; Bokobza, C.
10.1101/2024.02.07.579307 — physiology — Posted on 2024-02-07
3564 Building and analyzing metacells in single-cell genomics data
Bilous, M.; Herault, L.; Gabriel, A. A.; Teleman, M.; Gfeller, D.
10.1101/2024.02.04.578815 — bioinformatics — Posted on 2024-02-08
3565 A real-time, high-performance brain-computer interface for finger decoding and quadcopter control
Willsey, M. S.; Shah, N. P.; Avansino, D. T.; Hahn, N. V.; Jamiolkowski, R. M.; Kamdar, F. B.; Hochberg, L. R.; Willett, F. R.; Henderson, J. M.
10.1101/2024.02.06.578107 — bioengineering — Posted on 2024-02-08
3566 BayVarC: an ultra-sensitive ctDNA variant caller using Bayesian approach
Che, D.; Yan, C.; Zha, J.; Niu, Z.; Yang, Q.; Cheng, X.; Han, M.; Du, C.; Zhang, K.; Hu, Y.; Yang, Y.-F.
10.1101/2024.02.03.578772 — bioinformatics — Posted on 2024-02-07
3567 Personalized Molecular Signatures of Insulin Resistance and Type 2 Diabetes
Larsen, J.; Stocks, B.; Henderson, J.; Andersson, D.; Backdahl, J.; Eriksson-Hogling, D.; Stidsen, J.; Sakamoto, K.; Hojlund, K.; Ryden, M.; Zierath, J. R.; Krook, A.; Deshmukh, A. S.
10.1101/2024.02.06.578994 — biochemistry — Posted on 2024-02-07
3570 Influence of S100A9 on Prion Protein Amyloid Aggregation
Ziaunys, M.; Sulskis, D.; Mikalauskaite, K.; Sakalauskas, A.; Smirnovas, V.
10.1101/2024.02.06.579161 — biochemistry — Posted on 2024-02-07
3571 Beta-Glucanase superfamily identified by sequential, functional, and structural analyses
Nakajima, M.; Tanaka, N.; Motouchi, S.; Kobayashi, K.; Shimizu, H.; Abe, K.; Hosoyamada, N.; Abara, N.; Morimoto, N.; Hiramoto, N.; Nakata, R.; Takashima, A.; Hosoki, M.; Suzuki, S.; Shikano, K.; Fujimaru, T.; Imagawa, S.; Kawadai, Y.; Wang, Z.; Kitano, Y.; Nihira, T.; Nakai, H.; Taguchi, H.
10.1101/2024.02.06.578578 — biochemistry — Posted on 2024-02-07
3572 Formylation facilitates the reduction of oxidized initiator methionines
Tan, R.; Hoare, M.; Bellomio, P.; Broas, S.; Camacho, K.; Swovick, K.; Welle, K. A.; Hryhorenko, J. R.; Ghaemmaghami, S.
10.1101/2024.02.06.579201 — biochemistry — Posted on 2024-02-07
3573 Peripheral mutations underlie promiscuous transport of quaternary ammonium antiseptics by Small Multidrug Resistance transporters
Burata, O. E.; O'Donnell, E.; Hyun, J.; Lucero, R. M.; Thomas, J. E.; Gibbs, E. M.; Reacher, I.; Carney, N. A.; Stockbridge, R. B.
10.1101/2024.02.06.579181 — biochemistry — Posted on 2024-02-07
3575 Assessment of salivary microRNA by RT-qPCR: Challenges in data interpretation for clinical diagnosis
Van Der Hofstadt, M.; Cardinal, A.; Lepeltier, M.; Boulestreau, J.; Ouedraogo, A.; Kahli, M.; Molina, L.; Molina, F.; Van, T. N. N.
10.1101/2024.02.06.579150 — molecular biology — Posted on 2024-02-07
3576 Rendering the metabolic wiring powering wetland soil methane production
Oliverio, A. M.; Narrowe, A. B.; Villa, J. A.; Rinke, C.; Hoyt, D. W.; Liu, P.; McGivern, B. B.; Bechtold, E. K.; Ellenbogen, J. B.; Daly, R. A.; Smith, G. J.; Angle, J. C.; Flynn, R. M.; Freiburger, A. P.; Louie, K. B.; Stemple, B.; Northen, T.; Henry, C.; Miller, C.; Morin, T. H.; Bohrer, G.; Borton, M. A.; Wrighton, K. C.
10.1101/2024.02.06.579222 — microbiology — Posted on 2024-02-07
3577 Ultra-high efficiency T cell reprogramming at multiple loci with SEED-Selection
Chang, C. R.; Vykunta, V. S.; Goodman, D. B.; Muldoon, J. J.; Nyberg, W. A.; Liu, C.; Allain, V.; Rothrock, A.; Wang, C. H.; Marson, A.; Shy, B. R.; Eyquem, J.
10.1101/2024.02.06.576175 — synthetic biology — Posted on 2024-02-07
3584 Sensory neuron population expansion enhances odour tracking without sensitising projection neurons
Takagi, S.; Sancer, G.; Abuin, L.; Stupski, S. D.; Arguello, J. R.; Prieto-Godino, L. L.; Stern, D. L.; Cruchet, S.; Alvarez-Ocana, R.; Wienecke, C. F. R.; van Breugel, F.; Jeanne, J. M.; Auer, T. O.; Benton, R.
10.1101/2023.09.15.556782 — neuroscience — Posted on 2024-02-07
3585 Optimal Performance Objectives in the Highly Conserved Bone Morphogenetic Protein Signaling Pathway
Shaikh, R.; Larson, N. J.; Hanjaya-Putra, D.; Zartman, J. J.; Umulis, D. M.; Li, L.; Reeves, G. T.
10.1101/2024.02.01.578451 — systems biology — Posted on 2024-02-07
3586 Regulation of a single Inositol 1-Phosphate Synthase homeolog by HSFA6B contributes to fiber yield maintenance under drought conditions in upland cotton
Yu, L.; Nelson Dittrich, A. C.; Zhang, X.; Thirumalaikumar, V. P.; Melandri, G.; Skirycz, A.; Thorp, K. R.; Hinze, L. L.; Nelson, A. D. L.; Pauli, D.
10.1101/2022.06.10.495687 — plant biology — Posted on 2024-02-07
3587 Phenotypic, genomic, and transcriptomic heterogeneity in a pancreatic cancer cell line
Xie, G.; Zhang, L.; Usman, O. H.; Kumar, S.; Modak, C.; Patel, D.; Kavanaugh, M.; Mallory, X.; Wang, Y. J.; Irianto, J.
10.1101/2022.11.11.516211 — cancer biology — Posted on 2024-02-07
3588 Structural insights into the orthosteric inhibition of P2X receptors by non-ATP-analog antagonists
Sheng, D.; Yue, C.; Jin, F.; Wang, Y.; Ichikawa, M.; Yu, Y.; Guo, C.-R.; Hattori, M.
10.1101/2023.09.15.558037 — biophysics — Posted on 2024-02-07
3590 Kinase activity of histone chaperone APLF maintains steady state of centrosomes in mouse embryonic stem cells
Dutta, D.; Rajam, S. M.; Varghese, P. C.; Shirude, M. B.; Syed, K. M.; Devarajan, A.; Natarajan, K.
10.1101/2024.02.06.579158 — biochemistry — Posted on 2024-02-07
3591 Characterization, structure and inhibition of the human succinyl-CoA:glutarate-CoA transferase, a genetic modifier of glutaric aciduria type 1
Khamrui, S.; Dodatko, T.; Wu, R.; Leandro, J.; Sabovic, A.; Violante, S.; Cross, J. R.; Marsan, E.; Kumar, K.; DeVita, R.; Lazarus, M. B.; Houten, S.
10.1101/2024.02.07.578422 — biochemistry — Posted on 2024-02-07
3593 CD81-guided heterologous EVs present heterogeneous interactions with breast cancer cells
Gurrieri, E.; Carradori, G.; Roccuzzo, M.; Pancher, M.; Peroni, D.; Belli, R.; Trevisan, C.; Notarangelo, M.; Huang, W.-Q.; Carreira, A. S.; Quattrone, A.; Jenster, G.; Ten Hagen, T. L.; D'Agostino, V. G.
10.1101/2024.02.06.579138 — molecular biology — Posted on 2024-02-07
3594 Localization of Human UBE3A Isoform 3 is Highly Sensitive to Amino Acid Substitutions at p.Met21 Position
van Esbroeck, A. C. M.; Verhagen, R. F. M.; Biagioni, M.; Fossati, M.; Distel, B.; Elgersma, Y.
10.1101/2024.02.05.578859 — molecular biology — Posted on 2024-02-07
3596 Interplay of condensation and chromatin binding underlies BRD4 targeting
Strom, A. R.; Eeftens, J. M.; Polyachenko, Y.; Weaver, C. J.; Watanabe, H.-F.; Bracha, D.; Orlovsky, N. D.; Jumper, C. C.; Jacobs, W. M.; Brangwynne, C. P.
10.1101/2024.02.07.579384 — molecular biology — Posted on 2024-02-07
3597 Catalytic-independent functions of INTAC in conferring sensitivity to BET inhibition
FAN, P.; SHANG, X.-Y.; SONG, A.; CHEN, S.; MAO, R.-Y.; CHEN, J.; WANG, Z.; ZHENG, H.; TAO, B.; XU, W.; JIANG, W.; YANG, H.; XU, C.; ZHANG, P.; Jiang, H.; CHEN, F. X.
10.1101/2024.02.07.579305 — molecular biology — Posted on 2024-02-07
3598 Small molecule inhibitors of hnRNPA2B1-RNA interactions reveal a predictable sorting of RNA subsets into extracellular vesicles
Corsi, J.; Peroni, D.; Belli, R.; Lassandro, M.; Sidarovich, V.; Adami, V.; Grosskreutz, J.; Fabbiano, F.; Grossmann, D.; Hermann, A.; Tell, G.; Basso, M.; D'Agostino, V. G.
10.1101/2024.02.05.578546 — molecular biology — Posted on 2024-02-07
3599 A rapid, cost-effective, colorimetric LAMP assay (CLASS) for detecting invasive malaria vector, Anopheles stephensi
Rafferty, C.; Raise, G.; Scaife, J.; Abongo, B.; Omondi, S.; Milanoi, S.; Muchoki, M.; Onyango, B.; Ochomo, E.; Zohdy, S.
10.1101/2024.02.06.579110 — molecular biology — Posted on 2024-02-07
3600 Polyketide synthase-derived sphingolipids determine microbiota-mediated protection against pathogens in C. elegans
Peters, L.; Drechsler, M.; Pees, B.; Angelidou, G.; Salzer, L.; Moors, K. A.; Paczia, N.; Schulenburg, H.; Shi, Y.-M.; Kaleta, C.; Witting, M.; Bode, H. B.; Dierking, K.
10.1101/2024.02.06.579051 — molecular biology — Posted on 2024-02-07
3601 Substrate stiffness modulates the emergence and magnitude of senescence phenotypes
Starich, B.; Yang, F.; Tanrioven, D.; Kung, H.-C.; Baek, J.; Nair, P. R.; Kamat, P.; Macaluso, N.; Eoh, J.; Han, K. S.; Gu, L.; Sun, S.; Wu, P.-H.; Wirtz, D.; Phillip, J. M.
10.1101/2024.02.06.579151 — molecular biology — Posted on 2024-02-07
3602 DOT1L stimulates MYC/Mondo transcription factor activity by promoting its degradation cycle on chromatin
Sepulveda, G. P.; Gushchanskaia, E. S.; Mora-Martin, A.; Esse, R.; Nikorich, I.; Ceballos, A.; Kwan, J.; Blum, B. C.; Dholiya, P.; Emili, A.; Perissi, V.; Cardamone, M. D.; Grishok, A.
10.1101/2024.02.06.579191 — molecular biology — Posted on 2024-02-07
3604 PluMu - a Mu-like bacteriophage infecting Actinobacillus pleuropneumoniae
Bartsch, L. J.; Fernandez Crespo, R.; Wang, Y.; Skinner, M. A.; Rycroft, A. N.; Cooley, W.; Everest, D. J.; Li, Y.; Bosse, J. T.; Langford, P. R.
10.1101/2024.02.07.579279 — microbiology — Posted on 2024-02-07
3605 The Streptococcus pyogenes M protein is involved in phenotypic resistance to phage A25 infection in presence of human serum.
Schiavolin, L.; Steinmetz, J.; Botquin, G.; Delforge, V.; Lakhloufi, D.; Smeesters, P. R.; Botteaux, A.
10.1101/2024.02.07.579182 — microbiology — Posted on 2024-02-07
3608 Single-cell trait diversity explains niche and fitness differences in aquatic microbial communities
Fontana, S.; Schmitz, D. A.; Daniels, M.; Danza, F.; Röösli, T.; Bruderer, H.; Walser, J.-C.; Dekaezemacker, J.; Escrig, S.; Meibom, A.; Pomati, F.; Schreiber, F.
10.1101/2024.02.07.579265 — microbiology — Posted on 2024-02-07
3609 Exploring the metabolic potential of Aeromonas to utilise the carbohydrate polymer chitin
Tugui, C.; Sorokin, D.; Hijnen, W.; Wunderer, J.; Bout, K.; van Loosdrecht, M.; Pabst, M.
10.1101/2024.02.07.579344 — microbiology — Posted on 2024-02-07
3614 Enhancing Plant Photosynthesis using Carbon Dots as Light Converter and Photosensitizer
Hu, H.; Cheng, W.; Wang, X.; Yang, Y.; Yu, X.; Ding, J.; Lin, Y.; Zhao, W.; Zhao, Q.; Ledesma-Amaro, R.; Chen, X.; Liu, J.; Yang, C.; Gao, X.
10.1101/2024.02.06.579025 — synthetic biology — Posted on 2024-02-07
3615 Lipoxin A4 yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling
Koudelka, A.; Buchan, G. J.; Cechova, V.; O`Brien, J. P.; Liu, H.; Woodcock, S. R.; Mullett, S. J.; Zhang, C.; Freeman, B. A.; Gelhaus, S. L.
10.1101/2024.02.06.579101 — biochemistry — Posted on 2024-02-07
3618 Diversity, Origin and Evolution of the ESCRT Systems
Makarova, K. S.; Tobiasson, V.; Wolf, Y. I.; Lu, Z.; Liu, Y.; Zhang, S.; Krupovic, M.; Li, M.; Koonin, E. V.
10.1101/2024.02.06.579148 — evolutionary biology — Posted on 2024-02-07
3619 Multiple plastid losses within photosynthetic stramenopiles revealed by comprehensive phylogenomics
Terpis, K.; Salomaki, E.; Barcyte, D.; Panek, T.; Verbruggen, H.; Kolisko, M.; Bailey, J. C.; Elias, M.; Lane, C.
10.1101/2024.02.03.578753 — evolutionary biology — Posted on 2024-02-07
3621 miR-203 controls timing of developmental transitions during early preimplantation embryogenesis
Gonzalez-Martinez, J.; Ayala, E.; Sanchez-Belmonte, A.; Garcia, A.; Nogueira, E.; Melati, A.; Gimenez, D.; Losada, A.; Ortega, S.; Malumbres, M.
10.1101/2024.02.06.579214 — developmental biology — Posted on 2024-02-07
3622 Genetic Studies Highlight the Role of TET2 and INO80 in DNA Damage Response and Kidney Disease Pathogenesis
Liang, X.; Liu, H.; Hu, H.; Zhou, J.; Abedini, A.; Navarro, A. S.; Klotzer, K. A.; Susztak, K.
10.1101/2024.02.02.578718 — genetics — Posted on 2024-02-07
3624 Shift in cellular crosstalk reveals the immunosuppressive environment in cholangiocarcinoma patients.
Heij, L. R.; Hayat, S.; Reichel, K.; Maryam, S.; Rourke, C.; Tan, X.; van den Braber, M.; Verhoeff, J.; Halder, M.; Peisker, F.; Wiltberger, G.; Bednarsch, J.; Heise, D.; Campello Deierl, J.; Lang, S.; Ulmer, F.; Luedde, T.; Dahl, E.; Jonigk, D.; Nolting, J.; Sivakumar, S.; Siveke, J.; Rocha, F.; Baba, H.; Andersen, J.; Garcia Vallejo, J.; Kramann, R.; Neumann, U.
10.1101/2024.02.03.578669 — cancer biology — Posted on 2024-02-07
3625 Modeling reveals the strength of weak interactions in stacked ring assembly
Lagunes, L.; Briggs, K.; Martin-Holder, P.; Xu, Z.; Maurer, D.; Ghabra, K.; Deeds, E. J.
10.1101/2024.02.02.578706 — biophysics — Posted on 2024-02-07
3629 Alterations of Pleiotropic Neuropeptide-Receptor gene couples in Cetacea
Valente, R.; Cordeiro, M.; Pinto, B.; Machado, A.; Alves, F.; Sousa Pinto, I.; Ruivo, R.; Castro, L. F. C.
10.1101/2024.02.03.578746 — evolutionary biology — Posted on 2024-02-07
3630 IFNγ induces epithelial reprogramming driving CXCL11-mediated T cell migration
Cutilli, A.; Jansen, S. A.; Paolucci, F.; Mokry, M.; Mocholi, E.; Lindemans, C. A.; Coffer, P. J.
10.1101/2024.02.03.578580 — immunology — Posted on 2024-02-07
3632 Probing PAC1 receptor activation across species with an engineered sensor
Cola, R. B.; Niethammer, S. N.; Rajamannar, P.; Gresch, A.; Bhat, M. A.; Assoumou, K.; Williams, E. T.; Hauck, P.; Hartrampf, N.; Benke, D.; Stoeber, M.; Levkowitz, G.; Melzer, S.; Patriarchi, T.
10.1101/2024.02.06.579048 — neuroscience — Posted on 2024-02-07
3633 Nandrolone alters the behavioral response to cocaine as well as striatal and cortical dopamine receptors of prepubertal male rats.
Freire-Arvelo, J. A.; Rivero, C. J.; Santiago-Marrero, I. G.; Mendez-Morales, A.; Gonzalez-Segarra, A. J.; Perez-Cardona, E. U.; Torres-Ramirez, R. J.; Segarra, A. C.
10.1101/2024.02.07.579337 — neuroscience — Posted on 2024-02-07
3634 Nanoligomers targeting NF-κB and NLRP3 reduce neuroinflammation and improve cognitive function with aging and tauopathy
Wahl, D.; Risen, S. J.; Osburn, S. C.; Emge, T.; Sharma, S.; Gilberto, V. S.; Chatterjee, A.; Moreno, J. A.; LaRocca, T. J.
10.1101/2024.02.03.578493 — physiology — Posted on 2024-02-07
3635 Spatial transcriptomics of healthy and fibrotic human liver at single-cell resolution
Watson, B.; Paul, B.; Amir-Zilberstein, L.; Segerstolpe, A.; Rahman, R.; Shih, A.; Deguine, J.; Xavier, R.; Moffitt, J. R.; Mullen, A. C.
10.1101/2024.02.02.578633 — genomics — Posted on 2024-02-07
3637 Cell Cycle-Dependent TICRR/TRESLIN and MTBP Chromatin Binding Mechanisms and Patterns
Noble, T. D.; Sansam, C. G.; Wittig, K. A.; Majchrzycka, B.; Sansam, C. L.
10.1101/2024.02.02.578516 — genomics — Posted on 2024-02-07
3642 Devaluation of response-produced safety signals reveals circuits for goal-directed versus habitual avoidance in dorsal striatum
Sears, R. M.; Andrade, E.; Samels, S. B.; Laughlin, L. C.; Moloney, D. M.; Wilson, D. A.; Alwood, M. R.; Moscarello, J. M.; Cain, C. K.
10.1101/2024.02.07.579321 — neuroscience — Posted on 2024-02-07
3644 Standard rodent diets differentially impact alcohol consumption and preference and gut microbiome diversity
Zaparte, A.; Dore, E.; White, S.; Paliarin, F.; Gabriel, C.; Copenhaver, K.; Basavanhalli, S.; Garcia, E.; Vaddavalli, R.; Luo, M.; Taylor, C. M.; Welsh, D.; Maiya, R.
10.1101/2024.02.06.579237 — neuroscience — Posted on 2024-02-07
3646 Neuronal potassium channel activity triggers initiation of mRNA translation through binding of translation regulators
Malone, T. J.; Wu, J.; Zhang, Y.; Licznerski, P.; Chen, R.; Nahiyan, S.; Pedram, M.; Jonas, E. A.; Kaczmarek, L. K.
10.1101/2024.02.07.579306 — neuroscience — Posted on 2024-02-07
3649 Striatal dopamine contributions to skilled motor learning
Phillips, C. D.; Myers, C. C.; Leventhal, D. K.; Burgess, C. R.
10.1101/2024.02.06.579240 — neuroscience — Posted on 2024-02-07
3651 Gene Regulatory Network topology governs resistance and treatment escape in glioma stem-like cells
Park, J. H.; Hothi, P.; Lopez Garcia de Lomana, A.; Pan, M.; Calder, R.; Turkarslan, S.; Wu, W.-J.; Lee, H.; Patel, A. P.; Cobbs, C.; Huang, S.; Baliga, N. S.; Baliga, N. S.
10.1101/2024.02.02.578510 — systems biology — Posted on 2024-02-07
3652 Science Education for the Youth (SEFTY): A Neuroscience Outreach Program for High School Students in Southern Nevada During the COVID-19 Pandemic
Ghani, N.; Baker, H.; Huntsinger, A.; Chen, T.; Familara, T. D.; Itorralba, J. Y.; Vanderford, F.; Zhuang, X.; Chang, C.-L.; Vo, V.; Oh, E.
10.1101/2024.02.02.578716 — scientific communication and education — Posted on 2024-02-07
3653 ATP Citrate Lyase Drives Vascular Remodeling Diseases Development Through Metabolic-Epigenetic Reprograming.
Grobs, Y.; Romanet, C.; Lemay, S.-E.; Bourgeois, A.; Voisine, P.; Theberge, C.; Sauvaget, M.; Breuils-Bonnet, S.; Martineau, S.; El-kabbout, R.; Mougin, M.; Dumais, E.; Perron, J.; Flamand, N.; Potus, F.; Provencher, S.; Boucherat, O.; Bonnet, s.
10.1101/2024.02.02.578545 — physiology — Posted on 2024-02-07
3654 Intermittent energy restriction inhibits tumor growth and enhances paclitaxel response in a transgenic mouse model of endometrial cancer
Zhao, Z.; Wang, J.; Kong, W.; Fang, Z.; Coleman, M.; Milne, G.; Burkett, W. C.; Newton, M. A.; Lee, D.; Deng, B.; Shen, X.; Suo, H.; Sun, W.; Hursting, S.; Zhou, C.; Bae-Jump, V. L.
10.1101/2024.02.02.578679 — cancer biology — Posted on 2024-02-07
3655 Commonly used software tools produce conflicting and overly-optimistic AUPRC values
Chen, W.; Miao, C.; Zhang, Z.; Fung, C. S.-H.; Wang, R.; Chen, Y.; Qian, Y.; Cheng, L.; Yip, K.; Tsui, S. K.-W.; Cao, Q.
10.1101/2024.02.02.578654 — bioinformatics — Posted on 2024-02-07
3658 Deciphering Endothelial and Mesenchymal Organ Specification in Vascularized Lung and Intestinal Organoids
Miao, Y.; Tan, C.; Pek, N. M.; Yu, Z.; Iwasawa, K.; Kechele, D. O.; Sundaram, N.; Pastrana-Gomez, V.; Kishimoto, K.; Yang, M.-c.; Jiang, C.; Tchieu, J.; Whitsett, J. A.; McCracken, K. W.; Rottier, R. J.; Kotton, D. N.; Helmrath, M. A.; Wells, J. M.; Takebe, T.; Zorn, A. M.; Chen, Y.-W.; Guo, M.; Gu, M.
10.1101/2024.02.06.577460 — developmental biology — Posted on 2024-02-07
3661 TPPB modulates PKC activity to attenuate neuroinflammation and ameliorate experimental multiple sclerosis
Shanmukha, S.; Godfrey, W. H.; Gharibani, P.; Lee, J. J.; Guo, Y.; Deng, X.; Wender, P. A.; Kornberg, M. D.; Kim, P. M.
10.1101/2024.02.02.578637 — immunology — Posted on 2024-02-07
3662 Transthyretin orchestrates vitamin B12-induced stress resilience
Stein, G.; Aly, J. S.; Manzolillo, A.; Lange, L.; Riege, K.; Hussain, I.; Heller, E. A.; Cubillos, S.; Ernst, T. A.; Huebner, C. A.; Turecki, G.; Hoffmann, S.; Engmann, O.
10.1101/2024.02.07.578164 — neuroscience — Posted on 2024-02-07
3663 SpiDa-MRI, behavioral and (f)MRI data of adults with fear of spiders
Zhang, M.; Karner, A.; Kostorz, K.; Shea, S.; Steyrl, D.; Melinscak, F.; Sladky, R.; Lor, C. S.; Scharnowski, F.
10.1101/2024.02.07.578564 — neuroscience — Posted on 2024-02-07
3665 Lack of rhythmicity in Bmal1 deficient mice impairs motivation towards natural stimuli.
Berbegal-Saez, P.; Gallego-Landin, I.; Macia, J.; Alegre-Zurano, L.; Castro-Zavala, A.; Welz, P.-S.; Benitah, S. A.; Valverde, O.
10.1101/2024.02.07.579260 — neuroscience — Posted on 2024-02-07
3666 Effort Drives Saccade Selection
Koevoet, D.; Van Zantwijk, L.; Naber, M.; Mathot, S.; Van der Stigchel, S.; Strauch, C.
10.1101/2024.02.06.579052 — neuroscience — Posted on 2024-02-07
3670 Genome-wide diversity in lowland and highland maize landraces from southern South America: population genetics insights to assist conservation
Dominguez, P. G.; Gutierrez, A. V.; Fass, M. I.; Filippi, C. V.; Vera, P.; Puebla, A.; Defacio, R. A.; Paniego, N. B.; Lia, V. V.
10.1101/2024.02.02.578655 — genomics — Posted on 2024-02-07
3671 Inhibition of CERS1 in skeletal muscle exacerbates age-related muscle dysfunction
Wohlwend, M.; Laurila, P.-P.; Goeminne, L.; Lima, T.; Daskalaki, I.; Li, X.; von Alvensleben, G.; Crisol, B.; Mangione, R.; Gallart-Ayala, H.; Burri, O.; Butler, S.; Morris, J.; Turner, N.; Ivanisevic, J.; Auwerx, J.
10.1101/2023.08.05.552113 — physiology — Posted on 2024-02-07
3677 On-farm hatching and contact with adult hen post hatch induce sex-dependent effects on performance and welfare in broiler chickens
Guilloteau, L. A.; Bertin, A.; Crochet, S.; Bagnard, C.; Hondelatte, A.; Ravon, L.; Schouler, C.; Germain, K.; Collin, A.
10.1101/2023.05.17.541117 — physiology — Posted on 2024-02-07
3681 Sex-Specific DNA Methylation and Gene Expression Changes in Mouse Placentas After Early Preimplantation Alcohol Exposure
Legault, L.-M.; Dupas, T.; Breton-Larrivee, M.; Filion-Bienvenue, F.; Lemieux, A.; Langford-Avelar, A.; McGraw, S.
10.1101/2023.09.30.560198 — developmental biology — Posted on 2024-02-07
3683 Alternative splicing of a potato disease resistance gene maintains homeostasis between development and immunity
Sun, B.; Huang, J.; Kong, L.; Gao, C.; Zhao, F.; Zhao, F.; Wang, T.; Shen, J.; Wang, L.; Wang, Y.; Halterman, D.; Dong, S.
10.1101/2023.06.09.544375 — plant biology — Posted on 2024-02-07
3686 A Novel, Open-Source Virtual Reality Platform for Dendritic Spine Analysis
Reimer, M. L.; Kauer, S. D.; Benson, C. A.; King, J. F.; Patwa, S.; Feng, S.; Estacion, M. A.; Bangalore, L.; Waxman, S.; Tan, A. M.
10.1101/2024.02.02.578597 — bioinformatics — Posted on 2024-02-07
3687 Optimization of liver graft function using a poly-pharmacological drug cocktail CEPT in a simulated transplant model
Kharga, A.; Mojoudi, M.; Chen, H.; Taggart, M. S.; Dinicu, A. T.; Ozgur, O. S.; Uygun, B.; Toner, M.; Tessier, S.; Yeh, H.; Markmann, J. F.; Longchamp, A.; Uygun, K.
10.1101/2024.02.02.578568 — bioengineering — Posted on 2024-02-07
3688 Transdifferentiation of Human Dental Pulp Mesenchymal Stem Cells into Spiral Ganglion-like Neurons
MESSAT, Y.; Martin-Fernandez, m.; ASSOU, S.; CHUNG, K.; Guerin, F.; Gergely, C.; Cuisinier, F.; ZINE, A.
10.1101/2024.02.02.578615 — bioengineering — Posted on 2024-02-07
3691 Unlocking the soundscape of coral reefs with artificial intelligence
Williams, B.; Belvanera, S. M.; Sethi, S. S.; Lamont, T. A. C.; Jompa, J.; Prasetya, M.; Richardson, L.; Weschke, E.; Hoey, A.; Beldade, R.; Mills, S. C.; Haguenauer, A.; Zuberer, F.; Simpson, S. D.; Curnick, D.; Jones, K. E.
10.1101/2024.02.02.578582 — ecology — Posted on 2024-02-07
3693 Quick-quick-slow: the foxtrot migration and dynamic non-breeding range
Pokrovsky, I.; Curk, T.; Dietz, A.; Fufachev, I.; Kulikova, O.; Rossler, S.; Wikelski, M.
10.1101/2023.03.13.532370 — ecology — Posted on 2024-02-07
3694 Complement-Activating Multimeric Immunotherapeutic Complexes for HER2-breast cancer immunotherapy
Seguin-Devaux, C.; Brandus, B.; Plesseria, J.-M.; Iserentant, G.; Servais, J.-Y.; Kanli, G.; Behrmann, I.; Zimmer, J.; COHEN, J. H.; Dervillez, X.
10.1101/2024.02.02.578619 — immunology — Posted on 2024-02-07
3697 Chronic activation of tubulin tyrosination in HCM mice and human iPSC-engineered heart tissues improves heart function
Pietsch, N.; Chen, C. Y.; Kupsch, S.; Bacmeister, L.; Geertz, B.; Herera-Rivero, M.; Voss, H.; Krämer, E.; Braren, I.; Westermann, D.; Schlüter, H.; Mearini, G.; Schlossarek, S.; van der Velden, J.; Caporizzo, M. A.; Lindner, D.; Prosser, B. L.; Carrier, L.
10.1101/2023.05.25.542365 — physiology — Posted on 2024-02-07
3700 GraphCompass: Spatial metrics for differential analyses of cell organization across conditions
Ali, M.; Kuijs, M.; Hediyeh-zadeh, S.; Treis, T.; Hrovatin, K.; Palla, G.; Schaar, A. C.; Theis, F. J.
10.1101/2024.02.02.578605 — bioinformatics — Posted on 2024-02-07
3711 Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair
Saul, D.; Doolittle, M. L.; Rowsey, J. L.; Froemming, M. N.; Kosinsky, R. L.; Vos, S. J.; Ruan, M.; LeBrasseur, N.; Chandra, A.; Pignolo, R.; Passos, J.; Farr, J. N.; Monroe, D.; Khosla, S.
10.1101/2024.02.01.578420 — physiology — Posted on 2024-02-07
3712 Safety, pharmacokinetics, and potential neurological interactions of ivermectin, tafenoquine and chloroquine in Rhesus Macaques
Vanachayangkul, P.; Kodchakorn, C.; Ta-aksorn, W.; Im-Erbsin, R.; Tungtaeng, A.; Tipthara, P.; Tarning, J.; Lugo-Roman, L. A.; Wojnarski, M.; Vesely, B. A.; Kobylinski, K. C.
10.1101/2024.02.01.578449 — pharmacology and toxicology — Posted on 2024-02-07
3717 Generating single-cell gene expression profiles for high-resolution spatial transcriptomics based on cell boundary images
Zhang, B.; Li, M.; Kang, Q.; Deng, Z.; Qin, H.; Su, K.; Feng, X.; Chen, L.; Liu, H.; Fang, S.; Zhang, Y.; Li, Y.; Brix, S.; Xu, X.
10.1101/2023.12.25.573324 — bioinformatics — Posted on 2024-02-07
3719 Persistent tailoring of MSC activation through genetic priming
Beauregard, M. A.; Bedford, G. C.; Brenner, D. A.; Sanchez Solis, L. D.; Nishiguchi, T.; Abhimanyu, ; Carrero Longlax, S.; Mahata, B.; Veiseh, O.; Wenzel, P. L.; DiNardo, A. R.; Hilton, I. B.; Diehl, M. R.
10.1101/2024.02.01.578489 — bioengineering — Posted on 2024-02-07
3720 Biochemical fractionation of human α-Synuclein in a Drosophila model of synucleinopathies
Imomnazarov, K.; Lopez-Scarim, J.; Bagheri, I.; Joers, V.; Tansey, M. G.; Martin-Pena, A.
10.1101/2024.02.05.579034 — biochemistry — Posted on 2024-02-07
3723 Identification and Structural Characterization of a mutant KRAS-G12V specific TCR restricted by HLA-A3
Sim, M. J. W.; Hanada, K.-i.; Stotz, Z. S.; Yu, Z.; Lu, J.; Brennan, P.; Quastel, M.; Gillespie, G.; Long, E. O.; Yang, J. C.; Sun, P. D.
10.1101/2024.02.01.578367 — immunology — Posted on 2024-02-07
3724 Multiomic ALS signatures highlight sex differences and molecular subclusters and identify the MAPK pathway as therapeutic target
Caldi Gomes, L.; Hänzelmann, S.; Hausmann, F.; Khatri, R.; Oller, S.; Parvaz, M.; Tzeplaeff, L.; Pasetto, L.; Gebelin, M.; Ebbing, M.; Holzapfel, C.; Fabrizio Columbro, S.; Scozzari, S.; Knöferle, J.; Cordts, I.; Demleitner, A. F.; Deschauer, M.; Dufke, C.; Sturm, M.; Zhou, Q.; Zelina, P.; Sudria-Lopez, E.; Haack, T. B.; Streb, S.; Kuzma-Kozakiewicz, M.; Edbauer, D.; Pasterkamp, R. J.; Laczko, E.; Rehrauer, H.; Schlapbach, R.; Carapito, C.; Bonetto, V.; Bonn, S.; Lingor, P.
10.1101/2023.08.14.553180 — neuroscience — Posted on 2024-02-07
3725 gMCSpy: Efficient and accurate computation of Genetic Minimal Cut Sets in Python
Rodriguez, C. J.; Barrena, N.; Olaverri-Mendizabal, D.; Ochoa, I.; Valcarcel, L. V.; Planes, F. J.
10.1101/2024.02.02.578370 — systems biology — Posted on 2024-02-07
3731 Before and after delisting: population dynamics of North Atlantic humpback whales over two decades in the Gulf of Maine
Robbins, J.; Berube, M.; Clapham, P. J.; Mattila, D. K.; Palsboll, P. J.; Asmutis-Silvia, R.; Hill, A.; Howes, L. J.; Landry, S.; Lonergan, S.; Schulte, D.; Tackaberry, J. E.; Weinrich, M. T.; Pace, R. M.
10.1101/2024.02.04.577870 — ecology — Posted on 2024-02-07
3732 Flexible foraging behaviour increases predator vulnerability to climate change
Gauzens, B.; Rosenbaum, B.; Kalinkat, G.; Boy, T.; Jochum, M.; Kortsch, S.; O'Gorman, E. J.; Brose, U.
10.1101/2021.05.05.442768 — ecology — Posted on 2024-02-07
3733 Visualizing sarcomere and cellular dynamics in skeletal muscle to improve cell therapies
Hüttemeister, J.; Rudolph, F.; Radke, M.; Fink, C.; Friedrich, D.; Preibisch, S.; Falcke, M.; Wagner, E.; Lehnart, S. E.; Gotthardt, M.
10.1101/2024.02.01.578471 — cell biology — Posted on 2024-02-07
3734 Turnover of PPP1R15A mRNA encoding GADD34 controls the molecular memory of the cellular integrated stress response
Magg, V.; Manetto, A.; Kopp, K.; Wu, C. C.; Naghizadeh, M.; Lindner, D.; Eke, L.; Welsch, J.; Kallenberger, S. M.; Schott, J.; Haucke, V.; Locker, N.; Stoecklin, G.; Ruggieri, A.
10.1101/2023.11.11.566686 — cell biology — Posted on 2024-02-07
3735 Skeletal muscle hypertrophy rewires glucose metabolism: an experimental investigation and systematic review
Baumert, P.; Mantyselka, S.; Schoenfelder, M.; Heiber, M.; Jacobs, M. J.; Swaminathan, A.; Minderis, P.; Dirmontas, M.; Kleigrewe, K.; Meng, C.; Gigl, M.; Ahmetov, I. I.; Venckunas, T.; Degens, H.; Ratkevicius, A.; Hulmi, J.; Wackerhage, H.
10.1101/2022.12.08.519580 — molecular biology — Posted on 2024-02-07
3736 Reconceptualizing programmed transcriptional slippage in RNA viruses
Valli, A. A.; Domingo-Calap, M. L.; Gonzalez de Pradena, A.; Garcia, J. A.; Cui, H.; Desbiez, C.; Lopez-Moya, J. J.
10.1101/2024.02.05.578984 — molecular biology — Posted on 2024-02-07
3737 Limit of detection of Salmonella ser. Enteritidis using culture-based versus culture-independent diagnostic approaches
Bradford, L. M.; Yao, L.; Anastasiadis, C.; Cooper, A. L.; Blais, B.; Deckert, A. E.; Reid-Smith, R. J.; Lau, C. H.-F.; Diarra, M. S.; Carrillo, C.; Wong, A.
10.1101/2024.02.05.578949 — microbiology — Posted on 2024-02-07
3738 Temperatures above 37°C increase virulence of a convergent Klebsiella pneumoniae sequence type 307 strain
Mueller, J. U.; Schwabe, M.; Swiatek, L.-S.; Heiden, S. E.; Schlüter, R.; Sittner, M.; Bohnert, J. A.; Becker, K.; Idelevich, E. A.; Guenther, S.; Eger, E.; Schaufler, K.
10.1101/2024.02.06.579160 — microbiology — Posted on 2024-02-07
3739 Hypermigration of macrophages through the concerted action of GRA effectors on NF-κB/p38 signaling and host chromatin accessibility potentiates Toxoplasma dissemination
ten Hoeve, A. L.; Rodriguez, M. E.; Säflund, M.; Michel, V.; Magimel, L.; Ripoll, A.; Yu, T.; Hakimi, M.-A.; Saeij, J. P.; Ozata, D. M.; Barragan, A.
10.1101/2024.02.06.579146 — microbiology — Posted on 2024-02-07
3740 Effects of excess phosphate on a coastal plankton community
Spilling, K.; Vanharanta, M.; Santoro, M.; Villena-Alemany, C.; Labrenz, M.; Grossart, H.-P.; Piwosz, K.
10.1101/2024.02.05.576994 — microbiology — Posted on 2024-02-07
3741 DBT is a metabolic switch for maintenance of proteostasis under proteasomal impairment
Hwang, R.-D.; Lu, Y.; Tang, Q.; Periz, G.; Park, G.; Li, X.; Liu, Y.; Zhang, T.; Wang, J.
10.1101/2023.09.12.556394 — neuroscience — Posted on 2024-02-07
3742 Predictive processing in biological motion perception: Evidence from human behavior
Elmas, H. O.; Er, S.; Rezaki, A. D.; Izgi, A.; Urgen, B. M.; Boyaci, H.; Urgen, B. A.
10.1101/2024.02.03.578729 — neuroscience — Posted on 2024-02-07
3743 αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation
Uboveja, A.; Huang, Z.; Buj, R.; Amalric, A.; Wang, H.; Tangudu, N. K.; Cole, A. R.; Megill, E.; Kantner, D.; Chatoff, A.; Ahmad, H.; Marcinkiewicz, M. M.; Disharoon, J. A.; Graff, S.; Dahl, E. S.; Hempel, N.; Stallaert, W.; Sidoli, S.; Bitler, B. G.; Long, D. T.; Snyder, N. W.; Aird, K. M.
10.1101/2024.02.06.578742 — cancer biology — Posted on 2024-02-07
3749 Cell cycle perturbation uncouples mitotic progression and invasive behavior in a post-mitotic cell
Martinez, M. A. Q.; Zhao, C.; Moore, F. E. Q.; Yee, C. S.; Zhang, W.; Shen, K.; Martin, B. L.; Matus, D. Q.
10.1101/2023.03.16.533034 — developmental biology — Posted on 2024-02-07
3751 ChAHP2 and ChAHP control diverse retrotransposons by complementary activities
Ahel, J.; Pandey, A.; Schwaiger, M.; Mohn, F.; Basters, A.; Kempf, G.; Andriollo, A.; Kaaij, L.; Hess, D.; Bühler, M.
10.1101/2024.02.05.578923 — molecular biology — Posted on 2024-02-07
3752 Cryptic proteins translated from deletion-containing viral genomes dramatically expand the influenza virus proteome
Ranum, J. N.; Ledwith, M. P.; Alnaji, F. G.; Diefenbacher, M.; Orton, R.; Sloan, E.; Guereca, M.; Feltman, E. M.; Smollett, K.; da Silva Filipe, A.; Conley, M.; Russell, A. B.; Brooke, C. B.; Hutchinson, E.; Mehle, A.
10.1101/2023.12.12.570638 — microbiology — Posted on 2024-02-07
3753 Transposon mutagenesis screen in Klebsiella pneumoniae identifies genetic determinants required for growth in human urine and serum
Gray, J.; Torres, V. V. L.; Goodall, E. C.; McKeand, S. A.; Scales, D.; Collins, C.; Wetherall, L.; Lian, Z. J.; Bryant, J. A.; Milner, M. T.; Dunne, K.; Icke, C.; Rooke, J.; Schneiders, T.; Lund, P. A.; Cunningham, A. F.; Cole, J. A.; Henderson, I. R.
10.1101/2023.05.31.543172 — microbiology — Posted on 2024-02-07
3755 Distinct dynamics and intrinsic properties in ventral tegmental area populations mediate reward association and motivation
Elum, J. E.; Szelenyi, E. R.; Juarez, B.; Murry, A. D.; Loginov, G.; Zamorano, C. A.; Gao, P.; Wu, G.; Ng-Evans, S.; Xu, X.; Golden, S. A.; Zweifel, L. S.
10.1101/2024.02.05.578997 — neuroscience — Posted on 2024-02-07
3761 Untargeted Pixel-by-Pixel Imaging of Metabolite Ratio Pairs as a Novel Tool for Biomedical Discovery in Mass Spectrometry Imaging
Cheng, H.; Miller, D.; Southwell, N.; Fischer, J.; Taylor, I.; Salbaum, M.; Kappen, C.; Hu, F.; Yang, C.; Gross, S.; D'Aurelio, M.; Chen, Q.
10.1101/2024.01.10.575105 — bioinformatics — Posted on 2024-02-07
3764 DNA density is a better indicator of a nuclear bleb than lamin B loss
Bunner, S.; Prince, K.; Srikrishna, K.; Pujadas, E. M.; Pellegrino, P.; Aiello, J.; McCarthy, A. A.; Lawlor, C.; Jagtap, S.; Kuklinski, A.; Yas, G.; LaPointe, N.; Eweka, I.; Eastin, E.; Jackson, O.; Chen, J.; Schramm von Blucher, I.; Hardy, J.; Backman, V.; Janssen, A.; Packard, M.; Dorfman, K.; Almassalha, L.; Bahiru, M. S.; Stephens, A. D.
10.1101/2024.02.06.579152 — cell biology — Posted on 2024-02-07
3765 Networked proteins redundantly interact with VAP27 and RABG3 to regulate membrane tethering at the vacuole and beyond
Kaiser, S.; Mehlhorn, D.; Ramirez Miranda, P.; Ries, F.; Sommer, F.; Schroda, M.; Schumacher, K.; Willmund, F.; Grefen, C.; Scheuring, D.
10.1101/2023.09.29.560113 — cell biology — Posted on 2024-02-07
3767 Small Molecule G-quadruplex Ligands are Antibacterial Candidates for Gram-negative Bacteria
Takebayashi, Y.; Ramos-Soriano, J.; Jiang, Y. J.; Samphire, J.; Belmonte-Reche, E.; O'Hagan, M. P.; Gurr, C.; Heesom, K. J.; Lewis, P. A.; Samernate, T.; Nonejuie, P.; Spencer, J.; Galan, M. C.
10.1101/2022.09.01.506212 — microbiology — Posted on 2024-02-07
3768 Hippocampal reactive neural stem cells are able to phagocytose and have an immunological molecular signature
Abiega, O.; Senovilla-Ganzo, R.; El-Ouraoui, M.; Muro Garcia, T.; Ruiz Clavijo, L.; Garcia Moreno, F.; Fitzsimons, C. P.; Martin Suarez, S.; Encinas Perez, J. M.
10.1101/2024.01.26.577346 — neuroscience — Posted on 2024-02-07
3770 Distinct patterns of genetic variation at low-recombining genomic regions represent haplotype structure
Ishigohoka, J.; Bascon-Cardozo, K.; Bours, A.; Fuss, J.; Rhie, A.; Mountcastle, J.; Haase, B.; Chow, W.; Collins, J.; Howe, K.; Uliano-Silva, M.; Fedrigo, O.; Jarvis, E. D.; Perez-Tris, J.; Illera, J. C.; Liedvogel, M.
10.1101/2021.12.22.473882 — evolutionary biology — Posted on 2024-02-07
3772 Protein-protein interactions with G3BPs drive stress granule condensation and gene expression changes under cellular stress
Liboy-Lugo, J. M.; Espinoza, C. A.; Sheu-Gruttadauria, J.; Park, J. E.; Xu, A.; Jowhar, Z.; Gao, A. L.; Carmona-Negron, J. A.; Wittmann, T.; Jura, N.; Floor, S. N.
10.1101/2024.02.06.579149 — cell biology — Posted on 2024-02-07
3776 Speech-induced suppression and vocal feedback sensitivity in human cortex
Ozker, M.; Yu, L.; Dugan, P.; Doyle, W.; Friedman, D.; Devinsky, O.; Flinker, A.
10.1101/2023.12.08.570736 — neuroscience — Posted on 2024-02-07
3777 Causal role of the angular gyrus in insight-driven memory reconfiguration
Grob, A.-M.; Heinbockel, H.; Milivojevic, B.; Doeller, C.; Schwabe, L.
10.1101/2023.08.18.553803 — neuroscience — Posted on 2024-02-07
3778 A non-image-forming visual circuit mediates the innate fear of heights
Shang, W.; Xie, S.; Feng, W.; Li, Z.; Jia, J.; Cao, X.; Shen, Y.; Li, J.; Shi, H.; Gu, Y.; Weng, S.-J.; Lin, L.; Pan, Y.-H.; Yuan, X.
10.1101/2023.05.27.542556 — neuroscience — Posted on 2024-02-07
3782 The BTB-ZF gene Bm-mamo regulates pigmentation in silkworm caterpillars
Wu, S.; Tong, X.; Peng, C.; Luo, J.; Zhang, C.; Lu, K.; Li, C.; Ding, X.; Duan, X.; Lu, Y.; Hu, H.; Tan, D.; Dai, F.
10.1101/2023.04.07.536007 — genetics — Posted on 2024-02-07
3783 The genome sequence of the Montseny horsehair worm, Gordionus montsenyensis sp. nov., a key resource to investigate Ecdysozoa evolution
Eleftheriadi, K.; Guiglielmoni, N.; Salces-Ortiz, J.; Vargas-Chavez, C.; Martinez-Redondo, G. I.; Gut, M.; Flot, J.-F.; Schmidt-Rhaesa, A.; Fernandez, R.
10.1101/2023.06.26.546503 — evolutionary biology — Posted on 2024-02-07
3784 Highly dynamic evolution of the chemosensory gene repertoire driven by gene gain and expansion across subterranean beetles
Balart-Garcia, P.; Bradford, T. M.; Beasley-Hall, P. G.; Polak, S.; Ribera, I.; Cooper, S. J.; Fernandez, R.
10.1101/2022.12.08.519422 — evolutionary biology — Posted on 2024-02-07
3786 Hiding in Plain Sight: Thymic CD8+FOXP3+Tregs sequester CD25 and are enriched in human tissues
Jarvis, L. B.; Howlett, S. K.; Coppard, V. B.; Rainbow, D. B.; Alkwai, S. B.; Ellis, L. B.; Georgieva, Z. B.; Suchanek, O. B.; Mousa, H. S.; Mahbubani, K. T.; Saeb-Parsy, K. B.; Wicker, L. S.; Jones, J. L.
10.1101/2023.12.24.573232 — immunology — Posted on 2024-02-07
3789 Ramping dynamics in the frontal cortex unfold over multiple timescales during motor planning
Affan, R. O.; Bright, I. M.; Pemberton, L.; Cruzado, N. A.; Scott, B. B.; Howard, M. O.
10.1101/2024.02.05.578819 — neuroscience — Posted on 2024-02-06
3790 PI3K/HSCB axis facilitates FOG1 nuclear translocation to promote erythropoiesis and megakaryopoiesis
Liu, G.; Hou, Y.; Jin, X.; Zhang, Y.; Sun, C.; Huang, C.; Ren, Y.; Gao, J.; Wang, X.; Jiang, X.
10.1101/2024.02.05.578960 — molecular biology — Posted on 2024-02-06
3792 Enhanced Sequence-Activity Mapping and Evolution of Artificial Metalloenzymes by Active Learning
Vornholt, T.; Mutny, M.; Schmidt, G. W.; Schellhaas, C.; Tachibana, R.; Panke, S.; Ward, T. R.; Krause, A.; Jeschek, M.
10.1101/2024.02.06.579157 — synthetic biology — Posted on 2024-02-06
3793 Towards a Survival Risk Prediction Model for Metastatic NSCLC Patients on Durvalumab Using Whole-Lung CT Radiomics
Patwardhan, K. A.; RaviPrakash, H.; Nikolaou, N.; Gonzalez-Garcia, I.; Salazar, J. D.; Metcalfe, P.; Reischl, J.
10.1101/2024.02.01.578458 — bioinformatics — Posted on 2024-02-06
3794 Protein interaction map of APOBEC3 enzyme family reveals deamination-independent role in cellular function
Jang, G. M.; Sudarsan, A. K. A.; Shayeganmehr, A.; Munhoz, E. P.; Lao, R.; Gaba, A.; Rodriguez, M. G.; Love, R. P.; Polacco, B. J.; Zhou, Y.; Krogan, N. J.; Kaake, R. M.; Chelico, L.
10.1101/2024.02.06.579137 — biochemistry — Posted on 2024-02-06
3795 Self-regulation of the DNA N6-adenine methyltransferase AMT1 in the unicellular eukaryote Tetrahymena thermophila
Duan, L.; Li, H.; Ju, A.; Zhang, Z.; Niu, J.; Zhang, Y.; Diao, J.; Kataoka, K.; Ma, H.; Song, N.; Gao, S.; Wang, Y.
10.1101/2024.02.06.579081 — genetics — Posted on 2024-02-06
3796 Environmental DNA from ethanol eluent of flowers reveals a widespread diversity in cowpea associated animal communities in Hainan Island
Chen, Q.; Yu, H.-L.; Lv, J.-X.; Wang, X.; Li, J.; Wu, M.-Y.; Shi, C.-H.; Xie, W.; Kong, X.-Y.; Huang, G.-H.
10.1101/2024.02.01.578371 — ecology — Posted on 2024-02-06
3797 Toward Sustainable Biocultural Tourism: An Integrated Spatial Analysis of Cultural and Biodiversity Richness in Colombia
Echeverri, A.; Batista, N. M.; Wolny, S.; Herrera-R, G. A.; Andrade-Rivas, F.; Bailey, A.; Cardenas-Navarrete, A.; Davila-Arenas, A.; Diaz-Salazar, A. F.; Hernandez, K. V.; Langhans, K. E.; Mateus Aguilar, B. E.; Levey, D. R.; Neill, A.; Nguyen, O.; Suarez-Castro, A. F.; Zapata, F.; Ocampo-Penuela, N.
10.1101/2024.02.01.578429 — ecology — Posted on 2024-02-06
3798 The global root exudate carbon flux
Chari, N. R.; Tumber-Davila, S. J.; Phillips, R. P.; Bauerle, T. L.; Brunn, M.; Hafner, B. D.; Klein, T.; Obersteiner, S.; Reay, M. K.; Ullah, S.; Taylor, B. N.
10.1101/2024.02.01.578470 — ecology — Posted on 2024-02-06
3799 Introducing synthetic thermostable RNase inhibitors to single-cell RNA-seq
Noble, J. C.; Lentini, A.; Hageman-Jensen, M.; Sandberg, R.; Reinius, B.
10.1101/2024.02.06.579116 — molecular biology — Posted on 2024-02-06
3801 YraN is a helicase-associated nuclease fostering extended recombination events by natural transformation
Hardy, L.; Plantade, J.; Morales, V.; Mazzamurro, F.; Rocha, E. P. C.; Polard, P.; Charpentier, X.
10.1101/2024.02.06.579203 — microbiology — Posted on 2024-02-06
3805 The MYCN oncoprotein and helicases DDX17 and DDX5 have opposite effects on the production of chimeric transcripts in neuroblastoma cells
Clerc, V.; Valat, J.; Grand, X.; Fontrodona, N.; Bazire, M.; Rama, N.; Auboeuf, D.; Gibert, B.; Mortreux, F.; Bourgeois, C. F.
10.1101/2024.02.05.578895 — molecular biology — Posted on 2024-02-06
3806 A Mycobacterium tuberculosis secreted virulence factor disrupts host snRNP biogenesis
Chauhan, K.; Passricha, N.; Kapoor, Y.; Datta, D.; Arora, N.; Das, M.; Rao, K.; Singh, L.; Dutt, R.; Sharma, R.; Sarkar, B.; Malakkar, B.; Kalam, H.; Saini, P.; Mehra, L.; Das, P.; Ahuja, V.; Singhal, A.; Nandicoori, V.; Kumar, D.
10.1101/2024.02.06.579120 — molecular biology — Posted on 2024-02-06
3808 Preservation of memory B cell homeostasis in an individual producing broadly neutralising antibodies against HIV-1
Griffith, S.; Muir, L.; Suchanek, O.; Hope, J.; Pade, C.; Gibbons, J. M.; Tuong, Z. K.; Fung, A.; Touizer, E.; Rees-Spear, C.; Nans, A.; Roustan, C.; Alguel, Y.; Fink, D.; Orkin, C.; Deayton, J.; Anderson, J.; Gupta, R. K.; Doores, K. J.; Cherepanov, P.; McKnight, A.; Clatworthy, M.; McCoy, L. E.
10.1101/2024.02.05.578789 — microbiology — Posted on 2024-02-06
3809 Deep mutational scanning reveals functional constraints and antigenic variability of Lassa virus glycoprotein complex
Carr, C. R.; Crawford, K. H.; Murphy, M.; Galloway, J. G.; Haddox, H. K.; Matsen, F. A.; Andersen, K. G.; King, N. P.; Bloom, J. D.
10.1101/2024.02.05.579020 — microbiology — Posted on 2024-02-06
3811 High-fat and high-carbohydrate diets worsen the mouse brain susceptibility to damage produced by enterohemorrhagic Escherichia coli Shiga toxin 2
Arenas-Mosquera, D.; Cerny, N.; Cangelosi, A.; Geoghegan, P. A.; Malchiodi, E. L.; De Marzi, M.; Pinto, A.; Goldstein, J.
10.1101/2024.02.06.579171 — microbiology — Posted on 2024-02-06
3812 Gene regulation of infection-associated L-tartrate metabolism in Salmonella enterica serovar Typhimurium
Rojas, V. K.; Winter, M. G.; Jimenez Lopez, A.; Tanner, N. W.; Crockett, S. L.; Spiga, L.; Hendrixson, D. R.; Winter, S. E.
10.1101/2024.02.05.578992 — microbiology — Posted on 2024-02-06
3815 Point mutation in a virus-like capsid drives symmetry reduction to form tetrahedral cages
Szyszka, T. N.; Andreas, M. P.; Lie, F.; Miller, L. M.; Adamson, L. S. R.; Fatehi, F.; Twarock, R.; Draper, B. E.; Jarrold, M. F.; Giessen, T. W.; Lau, Y. H.
10.1101/2024.02.05.579038 — biochemistry — Posted on 2024-02-06
3816 Combining Unity with machine vision to create low latency, flexible, and simple virtual realities
Ogawa, Y.; Aoukar, R.; Leibbrandt, R.; Manger, J.; Bagheri, Z.; Turnbull, L.; Johnston, C.; Kaushik, P.; Hemmi, J. M.; Nordstrom, K.
10.1101/2024.02.05.579029 — animal behavior and cognition — Posted on 2024-02-06
3817 Natural selection exerted by historical coronavirus epidemic(s): comparative genetic analysis in China Kadoorie Biobank and UK Biobank
Morris, S. C.; Lin, K.; Millwood, I. Y.; Yu, C.; Lv, J.; Pei, P.; Li, L.; Sun, D.; Davey Smith, G.; Chen, Z.; Walters, R. G.
10.1101/2024.02.06.579075 — genomics — Posted on 2024-02-06
3818 De novo mutations mediate phenotypic switching in an opportunistic human lung pathogen
Poret, A. J.; Schaefers, M. M.; Merakou, C.; Mansour, K. E.; Lagoudas, G. K.; Cross, A. R.; Goldberg, J. B.; Kishony, R.; Uluer, A. Z.; McAdam, A. J.; Blainey, P. C.; Vargas, S. O.; Lieberman, T. D.; Priebe, G. P.
10.1101/2024.02.06.579193 — microbiology — Posted on 2024-02-06
3819 Gut microbial-mediated polyphenol metabolism is restrained by parasitic whipworm infection and associated with altered immune function in mice
Andersen-Civil, A. I. S.; Arora, P.; Zhu, L.; Myhill, L. J.; Budeyri Gokgoz, N.; Castro-Mejia, J. L.; Leppa, M.; Hansen, L. H.; Lessard-Lord, J.; Salminen, J.-P.; Thamsborg, S. M.; Nielsen, D. S.; Desjardins, Y.; Williams, A. R.
10.1101/2024.02.06.579078 — microbiology — Posted on 2024-02-06
3820 Lytic bacteriophages interact with respiratory epithelial cells and induce the secretion of antiviral and proinflammatory cytokines
Zamora, P. F.; Reidy, T. G.; Armbruster, C. R.; Sun, M.; Van Tyne, D.; Turner, P. E.; Koff, J. L.; Bomberger, J. M.
10.1101/2024.02.06.579115 — microbiology — Posted on 2024-02-06
3821 Genetic dissection of the tissue-specific roles of type III effectors and phytotoxins in the pathogenicity of Pseudomonas syringae pv. syringae to cherry
Vadillo Dieguez, A.; Zeng, Z.; Mansfield, J. W.; Grinberg, N. F.; Lynn, S. C.; Gregg, A.; Connell, J.; Harrison, R. J.; Jackson, R. W.; Hulin, M. T.
10.1101/2024.02.06.578989 — microbiology — Posted on 2024-02-06
3823 Evolution of a Plasmid Regulatory Circuit Ameliorates Plasmid Fitness Cost
Elg, C. A.; Mack, E.; Rolfsmeier, M.; McLean, T. C.; Kosterlitz, O.; Soderling, E.; Narum, S.; Rowley, P. A.; Thomas, C. M.; Top, E. M.
10.1101/2024.02.05.579024 — microbiology — Posted on 2024-02-06
3825 Mapping glycoprotein structure reveals defining events in the evolution of the Flaviviridae
Mifsud, J. C. O.; Lytras, S.; Oliver, M. R.; Toon, K.; Costa, V. A.; Holmes, E. C.; Grove, J.
10.1101/2024.02.06.579159 — microbiology — Posted on 2024-02-06
3826 A retinotopic reference frame for space throughout human visual cortex
Szinte, M.; de Hollander, G.; Aqil, M.; Verissimo, I.; Dumoulin, S.; Knapen, T.
10.1101/2024.02.05.578862 — neuroscience — Posted on 2024-02-06
3827 Dysregulation of Neuropilin-2 Expression in Inhibitory Neurons Impairs Hippocampal Circuit Development Leading to Autism-Epilepsy Phenotype
Subramanian, D.; Eisenberg, C.; Huang, A.; Baek, J.; Naveed, H.; Komatireddy, S.; Shiflett, M. W.; Tran, T. S.; Santhakumar, V.
10.1101/2024.02.05.578976 — neuroscience — Posted on 2024-02-06
3828 Perineuronal nets in the rat medial prefrontal cortex alter hippocampal-prefrontal oscillations and reshape cocaine self-administration memories
Sorg, B. A.; Wingert, J. C.; Ramos, J. D.; Reynolds, S. X.; Gonzalez, A. E.; Rose, R. M.; Hegarty, D. M.; Aicher, S. A.; Bailey, L. G.; Brown, T. E.; Abbas, A. I.
10.1101/2024.02.05.577568 — neuroscience — Posted on 2024-02-06
3831 Explicit and implicit locomotor learning in individuals with chronic hemiparetic stroke
Wood, J. M.; Thompson, E. M.; Wright, H.; Festa, L.; Morton, S. M.; Reisman, D. S.; Kim, H. E.
10.1101/2024.02.04.578807 — neuroscience — Posted on 2024-02-06
3833 Wavelet Phase Coherence of Ictal Scalp EEG-Extracted Muscle Activity (SMA) as a Biomarker for Sudden Unexpected Death in Epilepsy (SUDEP)
Gravitis, A. C.; Sivendiran, K.; Tufa, U.; Zukotynski, K.; Chinvarun, Y.; Devinsky, O.; Wennberg, R.; Carlen, P. L.; Bardakjian, B. L.
10.1101/2024.02.04.578837 — neuroscience — Posted on 2024-02-06
3835 Neural ensembles that encode affective mechanical and heat pain in mouse spinal cord
Zhang, M.-D.; Kupari, J.; Su, J.; Hu, Y.; Magnusson, K. A.; Calvo-Enrique, L.; Usoskin, D.; Albisetti, G. A.; Leavitt, A. D.; Zeilhofer, H. U.; Hokfelt, T.; Lagerstrom, M. C.; Ernfors, P.
10.1101/2024.02.05.578816 — neuroscience — Posted on 2024-02-06
3837 Brain-controlled augmented hearing for spatially moving conversations in multi-talker environments
Choudhari, V.; Han, C.; Bickel, S.; Mehta, A. D.; Schevon, C.; McKhann, G. M.; Mesgarani, N.
10.1101/2024.02.05.579018 — neuroscience — Posted on 2024-02-06
3839 Proactive selective attention across competition contexts
Aguado-Lopez, B.; Palenciano, A. F.; Penalver, J. M. G.; Diaz-Gutierrez, P.; Lopez-Garcia, D.; Avancini, C.; Ciria, L. F.; Ruz, M.
10.1101/2024.02.06.579112 — neuroscience — Posted on 2024-02-06
3840 Feasibility of decoding covert speech in ECoG with aTransformer trained on overt speech
Komeiji, S.; Mitsuhashi, T.; Iimura, Y.; Suzuki, H.; Sugano, H.; Shinoda, K.; Tanaka, T.
10.1101/2024.02.05.578911 — neuroscience — Posted on 2024-02-06
3842 Brain Age Analysis and Dementia Classification using Convolutional Neural Networks trained on Diffusion MRI: Tests in Indian and North American Cohorts
Chattopadhyay, T.; Joshy, N. A.; Ozarkar, S. S.; Buwa, K. S.; Feng, Y.; Laltoo, E.; Thomopoulos, S. I.; Villalon-Reina, J. E.; Joshi, H.; Venkatasubramanian, G.; John, J. P.; Thompson, P. M.
10.1101/2024.02.04.578829 — neuroscience — Posted on 2024-02-06
3844 Human Motor Cortex Encodes Complex Handwriting Through a Sequence of Primitive Neural States
Qi, Y.; Zhu, X.; Xiong, X.; Yang, X.; Ding, N.; Wu, H.; Xu, K.; Zhu, J.; Zhang, J.; Wang, Y.
10.1101/2024.02.05.578548 — neuroscience — Posted on 2024-02-06
3845 Deep Normative Tractometry for Identifying Joint White Matter Macro- and Micro-structural Abnormalities in Alzheimer's Disease
Feng, Y.; Chandio, B. Q.; Villalon-Reina, J. E.; Benavidez, S.; Chattopadhyay, T.; Chehrzadeh, S.; Laltoo, E.; Thomopoulos, S. I.; Joshi, H.; Venkatasubramanian, G.; John, J. P.; Jahanshad, N.; Thompson, P. M.
10.1101/2024.02.05.578943 — neuroscience — Posted on 2024-02-06
3847 MEA-NAP compares microscale functional connectivity, topology, and network dynamics in organoid or monolayer neuronal cultures
Sit, T. P.; Feord, R. C.; Dunn, A. W.; Chabros, J.; Oluigbo, D.; Smith, H. H.; Burn, L.; Chang, E.; Boschi, A.; Yuan, Y.; Gibbons, G. M.; Khayat-Khoei, M.; De Angelis, F.; Hemberg, E.; Hemberg, M.; Lancaster, M. A.; Lakatos, A.; Eglen, S. J.; Paulsen, O.; Mierau, S. B.
10.1101/2024.02.05.578738 — neuroscience — Posted on 2024-02-06
3849 Multimodal brain age prediction using machine learning: combining structural MRI and 5-HT2AR PET derived features
Dörfel, R.; Arenas-Gomez, J. M.; Svarer, C.; Ganz, M.; Knudsen, G. M.; Svensson, J.; Plaven-Sigray, P.
10.1101/2024.02.05.578968 — neuroscience — Posted on 2024-02-06
3854 Brain and grammar: revealing electrophysiological basic structures with competing statistical models
Cometa, A.; Battaglini, C.; Artoni, F.; Greco, M.; Frank, R.; Repetto, C.; Bottoni, F.; Cappa, S. F.; Micera, S.; Ricciardi, E.; Moro, A.
10.1101/2024.02.06.579088 — neuroscience — Posted on 2024-02-06
3855 A next-generation, histological atlas of the human brain and its application to automated brain MRI segmentation
Casamitjana, A.; Mancini, M.; Robinson, E.; Peter, L.; Annunziata, R.; Althonayan, J.; Crampsie, S.; Blackburn, E.; Billot, B.; Atzeni, A.; Puonti, O.; Balbastre, Y.; Schmidt, P.; Hughes, J.; Augustinack, J.; Edlow, B. L.; Zollei, L.; Thomas, D.; Kliemann, D.; Bocchetta, M.; Strand, C.; Holton, J.; Jaunmuktane, Z.; Iglesias, J. E.
10.1101/2024.02.05.579016 — neuroscience — Posted on 2024-02-06
3859 Sleep need driven oscillation of glutamatergic synaptic phenotype
Vogt, K.; Kulkarni, A.; Pandey, R.; Dehnad, M.; Konopka, G.; Greene, R. W.
10.1101/2024.02.05.578985 — neuroscience — Posted on 2024-02-06
3860 A pharmacological toolkit for human microglia identifies Topoisomerase I inhibitors as immunomodulators for Alzheimer's disease
Haage, V. C.; Tuddenham, J. F.; Comandante-Lou, N.; Bautista, A.; Monzel, A.; Chiu, R.; Fujita, M.; Garcia, F. G.; Bhattarai, P.; Patel, R.; Buonfiglioli, A.; Idiarte, J.; Herman, M.; Rinderspacher, A.; Mela, A.; Zhao, W.; Argenziano, M. G.; Furnari, J. L.; Banu, M. A.; Landry, D. W.; Bruce, J. N.; Canoll, P.; Zhang, Y.; Nuriel, T.; Kizil, C.; Sproul, A. A.; de Witte, L. D.; Sims, P. A.; Menon, V.; Picard, M.; De Jager, P. L.
10.1101/2024.02.06.579103 — neuroscience — Posted on 2024-02-06
3861 Cortico-spinal Mechanisms of Periphery Neuromodulation induced Analgesia
Wei, Z.; Duan, Y.; Zhu, Y.; Lin, X.; Zhang, M.; Brooks, J. C. W.; Liu, Y.; Hu, L.; Kong, Y.
10.1101/2024.02.06.579059 — neuroscience — Posted on 2024-02-06
3862 Identifying Interpretable Latent Factors with Sparse Component Analysis
Zimnik, A. J.; Ames, K. C.; An, X.; Driscoll, L.; Lara, A. H.; Russo, A. A.; Susoy, V.; Cunningham, J. P.; Paninski, L.; Churchland, M. M.; Glaser, J. I.
10.1101/2024.02.05.578988 — neuroscience — Posted on 2024-02-06
3865 Visually Induced Involuntary Movements
Martin, A.; Bakshi, A.; Ventura, J.; Lackner, J. R.
10.1101/2024.02.06.578999 — neuroscience — Posted on 2024-02-06
3866 Predictive processing in biological motion perception: Evidence from human behavior
Elmas, H. O.; Er, S.; Boyaci, H.; Urgen, B. A.; Rezaki, A. D.; Izgi, A.; Urgen, B. M.
10.1101/2024.02.03.578729 — neuroscience — Posted on 2024-02-06
3871 BMI1 regulates human erythroid self-renewal through both gene repression and gene activation
McGrath, K. E.; Koniski, A. D.; Murphy, K.; Getman, M.; An, H. H.; Schulz, V. P.; Kim, A.; Zhang, B.; Schofield, T. L.; Papoin, J.; Blanc, L.; Kingsley, P. D.; Westhoff, C. M.; Gallagher, P. G.; Chou, S. T.; Steiner, L. A.; Palis, J.
10.1101/2024.02.02.578704 — cell biology — Posted on 2024-02-06
3872 Senolytic treatment depletes microglia and decreases severity of experimental autoimmune encephalomyelitis.
Drake, S. S.; Zaman, A.; Gianfelice, C.; Hua, E. M.- L.; Heale, K.; Afanasiev, E.; STRATTON, J. A.; Fournier, A.
10.1101/2024.02.05.579017 — neuroscience — Posted on 2024-02-06
3874 Restraining Wnt activation and intestinal tumorigenesis by a Rab35 dependent GTPase relay
Redhai, S.; Eang, T.; Boonekamp, K. E.; Rueter, S.; Klemens, T. C.; Leible, S.; Bahuguna, S.; Port, F.; Pavlovic, B.; Holzem, M.; Doll, R.; Rindtorff, N.; Valentini, E.; Schmitt, B.; Richter, K.; Engel, U.; Huber, W.; Boutros, M.
10.1101/2024.02.05.578891 — cancer biology — Posted on 2024-02-06
3876 Cellular (de)coordination in gliding motility and plectoneme formation
Rosko, J.; Cremin, K.; Locatelli, E.; Coates, M.; Duxbury, S. J. N.; Soyer, O. S.; Croft, K.; Randall, K.; Valeriani, C.; Polin, M.
10.1101/2024.02.06.579126 — biophysics — Posted on 2024-02-06
3879 Trophic niche partitioning in symbiotic marine invertebrates
Guibert, I.; Conti-Jerpe, I.; Pons, L.; Tayaban, K.; Sayco, S. L.; Cabaitan, P.; Conaco, C.; Baker, D. M.
10.1101/2024.02.05.578332 — ecology — Posted on 2024-02-06
3881 Fluctuating salinity during development impacts fish productivity
Chung, M.-H.; Noble, D. W. A.; Fox, R. J.; Harrison, L. M.; Jennions, M. D.
10.1101/2024.02.01.578515 — ecology — Posted on 2024-02-06
3882 A single-cell 3D spatiotemporal multi-omics atlas from Drosophila embryogenesis to metamorphosis
Wang, M.; Hu, Q.; Tu, Z.; Kong, L.; Yao, J.; Xiang, R.; Chen, Z.; Zhao, Y.; Zhou, Y.; Yu, T.; Wang, Y.; Jia, Z.; Ouyang, K.; Wang, X.; Bai, Y.; Lian, M.; Yang, Z.; Yang, T.; Chen, J.; Huang, Y.; Yin, N.; Mo, W.; Liang, W.; Liu, C.; Lin, X.; Liu, C.; Gu, Y.; Chen, W.; Liu, L.; Xu, X.; Hu, Y.
10.1101/2024.02.06.577903 — developmental biology — Posted on 2024-02-06
3885 Building Blocks of Understanding: Constructing a Reverse Genetics Platform for studying determinants of SARS-CoV-2 replication.
Olguin-Nava, M.; Bohn, P.; Hennig, T.; Boertlein, C.; Gribling-Burrer, A.-S.; Schmidt, N.; Caliskan, N.; Doelken, L.; Munschauer, M.; Smyth, R. P.
10.1101/2024.02.05.578560 — microbiology — Posted on 2024-02-06
3886 Effects of excess phosphate on a coastal plankton community
Spilling, K.; Vanharanta, M.; Santoro, M.; Villena-Alemany, C.; Labrenz, M.; Grossart, H.-P.; Piwosz, K.
10.1101/2024.02.05.576994 — microbiology — Posted on 2024-02-06
3887 Second Boost of Omicron SARS-CoV-2 S1 Subunit Vaccine Induced Broad Humoral Immune Responses in Elderly Mice
Kim, E.; Khan, M. S.; Ferrari, A.; Huang, S.; Kenniston, T. W.; Cassaniti, I.; Baldanti, F.; Gambotto, A.
10.1101/2024.02.05.578925 — immunology — Posted on 2024-02-06
3888 Identification and Structural Characterization of a mutant KRAS-G12V specific TCR restricted by HLA-A3
Sim, M. J. W.; Hanada, K.-i.; Stotz, Z. S.; Yu, Z.; Lu, J.; Brennan, P.; Quastel, M.; Gillespie, G.; Long, E. O.; Yang, J. C.; Sun, P. D.
10.1101/2024.02.01.578367 — immunology — Posted on 2024-02-06
3889 The Origin and Evolution of Orphan Genes: A Case Study in Tea Plant Family
Cheng, L.; Hao, Y.; Han, Q.; Qiao, Z.; Li, M.; Liu, D.; Yin, H.; Li, T.; Long, W.; Luo, S.; Gao, Y.; Zhang, Z.; Yu, H.; Sun, X.; ZHAO, Y.
10.1101/2024.02.01.578514 — bioinformatics — Posted on 2024-02-06
3890 Large-scale multi-omics analyses identified root-microbiome associations underlying plant nitrogen nutrition
Li, N.; Li, G.; Wang, D.; Ma, L.; Huang, X.; Bai, Z.; Wang, Y.; Luo, M.; Luo, Y.; Zhu, Y.; Cao, X.; Feng, Q.; Xu, Y.; Mu, J.; An, R.; Yang, C.; Chen, H.; Li, X.; Dong, Y.; Zhao, J.; Jiang, L.; Jiang, Y.; Reif, J. C.; Hochholdinger, F.; Chen, X.; Wang, D.; Zhang, Y.; Bai, Y.; Yu, P.
10.1101/2024.02.05.578621 — plant biology — Posted on 2024-02-06
3895 Variability in drought gene expression datasets highlight the need for community standardization
VanBuren, R.; Nguyen, A.; Marks, R. A.; Mercado, C.; Pardo, A.; Pardo, J.; Schuster, J.; St. Aubin, B.; Wilson, M. L.; Rhee, S. Y.
10.1101/2024.02.04.578814 — plant biology — Posted on 2024-02-06
3898 WITHDRAWN: Oncogenic KRASG12D extrinsically induces an immunosuppressive microenvironment in lung adenocarcinoma
Lasse-Opsahl, E.; Baliira, R.; Barravecchia, I.; McLintock, E.; Lee, J. M.; Ferris, S. F.; Espinoza, C. E.; Hinshaw, R.; Cavanaugh, S.; Robotti, M.; Brown, K.; Donahue, K.; Abdelmalak, K. Y.; Galban, C. J.; Frankel, T. L.; Zhang, Y.; Pasca di Magliano, M.; Galban, S.
10.1101/2024.01.16.568090 — cancer biology — Posted on 2024-02-06
3899 Host response during unresolved urinary tract infection alters mammary tissue homeostasis through collagen deposition and TIMP1
Henry, S.; Lewis, S. M.; Cyrill, S. L.; Callaway, M. K.; Chatterjee, D.; Somasundara, A. V. H.; Jones, G.; He, X. Y.; Caligiuri, G.; Ciccone, M. F.; Diaz, I. A.; Biswas, A.; Hernandez, E.; Ha, T.; Wilkinson, J. E.; EGEBLAD, M.; Tuveson, D.; Dos Santos, C. O.
10.1101/2024.02.05.578977 — developmental biology — Posted on 2024-02-06
3903 Depression Attenuates Caudate and Dorsolateral Prefrontal Cortex Alpha and Beta Power Response to Reward
Qian, H.; Johnson, G. W.; Hughes, N. C.; Paulo, D. L.; Zhao, Z.; Subramanian, D.; Dhima, K.; Bick, S. K.
10.1101/2024.02.05.578848 — neuroscience — Posted on 2024-02-06
3904 Genome-wide CRISPR screen identifies AC9 as a key regulator of ER calcium homeostasis involved in neuronal differentiation.
Wang, L.; Li, J.; Wang, Y.; Zhong, Z.; Wang, Y.; Huang, R.; Zhang, B.; Liu, P.; Ye, E.; Cao, R.; Ali, S.; Ke, Y.; Yang, J.; Yokoyama, T.; Liu, J.; Zhang, X.; Sakamoto, M.; Sun, L.; Zhou, Y.; Wang, Y.
10.1101/2024.02.05.578803 — cell biology — Posted on 2024-02-06
3905 Single cell multi-omics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response
Warfvinge, R.; Geironson Ulfsson, L.; Dhapola, P.; Safi, F.; Sommarin, M. N. E.; Soneji, S.; Hjorth-Hansen, H.; Mustjoki, S.; Richter, J.; Krishna Thakur, R.; Karlsson, G.
10.1101/2023.08.16.553504 — cancer biology — Posted on 2024-02-06
3913 Quantifying the fitness effects of resistance alleles with and without anthelmintic selection pressure using Caenorhabditis elegans
Shaver, A. O.; Miller, I. R.; Schaye, E. S.; Moya, N. D.; Collins, J. B.; Wit, J.; Blanco, A. H.; Shao, F. M.; Andersen, E. J.; Khan, S. A.; Paredes, G.; Andersen, E. C.
10.1101/2024.02.01.578300 — genetics — Posted on 2024-02-06
3917 Lineage-resolved analysis of embryonic gene expression evolution in C. elegans and C. briggsae
Large, C. R. L.; Khanal, R.; Hillier, L. W.; Huynh, C.; Kubo, C.; Kim, J.; Waterston, R.; Murray, J. I.
10.1101/2024.02.03.578695 — evolutionary biology — Posted on 2024-02-06
3919 Does method of field preparation affect survival and growth of juvenile Chinook salmon in agricultural floodplains?
Tallman, R.; Wampler, A.; Singer, G.; Jeffres, C.; Cocherell, D.; Colby, J.; Fangue, N.; Lusardi, R.; Rypel, A.
10.1101/2024.02.02.578246 — ecology — Posted on 2024-02-06
3923 Neural signatures of opioid-induced risk-taking behavior in the prelimbic prefrontal cortex
Quave, C. B.; Vasquez, A. M.; Aquino-Miranda, G.; Bora, E. P.; Chidomere, C. L.; Zhang, X. O.; Engelke, D. S.; Do-Monte, F. H.
10.1101/2024.02.05.578828 — neuroscience — Posted on 2024-02-06
3925 Distinct dynamics and intrinsic properties in ventral tegmental area populations mediate reward association and motivation
Elum, J. E.; Szelenyi, E. R.; Juarez, B.; Murry, A. D.; Loginov, G.; Zamorano, C. A.; Gao, P.; Wu, G.; Ng-Evans, S.; Xu, X.; Golden, S. A.; Zweifel, L. S.
10.1101/2024.02.05.578997 — neuroscience — Posted on 2024-02-06
3926 A Functional and Non-Homuncular Representation of the Larynx in the Primary Motor Cortex of Mice, a Vocal Non-Learner
Vargas, C. D. M.; Agravat, R. K.; Waidmann, E. N.; Bochalis, C.; Bermudez, H.; Giannakopoulos, T.; Jarvis, E. D.
10.1101/2024.02.05.579004 — neuroscience — Posted on 2024-02-06
3927 Examining the relationship between psychosocial adversity and inhibitory control: an fMRI study of children growing up in extreme poverty
Surani, Z.; Turesky, T. K.; Sullivan, E.; Shama, T.; Haque, R.; Islam, N.; Kakon, S. H.; Yu, X.; Petri, W. A.; Nelson, C.; Gaab, N.
10.1101/2024.02.05.578942 — neuroscience — Posted on 2024-02-06
3929 Exploiting threonine sidechains as molecular switches to modulate the fluorescence of genetically encoded biosensors
Leong, L. M.; Shin, S. C.; Rhee, J. K.; Kim, H.; Seong, J.; Woo, J.; Han, K.; Storace, D. A.; Baker, B. J.
10.1101/2022.04.25.489330 — neuroscience — Posted on 2024-02-06
3935 The Vps13-like protein BLTP2 is pro-survival and regulates phosphatidylethanolamine levels in the plasma membrane to maintain its fluidity and function
Banerjee, S.; Daetwyler, S.; Bai, X.; Michaud, M.; Jouhet, J.; Madhugiri, S.; Johnson, E.; Wang, C.-W.; Fiolka, R.; Toulmay, A.; Prinz, W. A.
10.1101/2024.02.04.578804 — cell biology — Posted on 2024-02-05
3936 Nuclear pores safeguard the integrity of the nuclear envelope
Taniguchi, R.; Orniacki, C.; Kreysing, J. P.; Zila, V.; Zimmerli, C. E.; Boehm, S.; Turonova, B.; Kraeusslich, H.-G.; Doye, V.; Beck, M.
10.1101/2024.02.05.578890 — cell biology — Posted on 2024-02-05
3938 Spatiotemporal profiling defines persistence and resistance dynamics during targeted treatment of melanoma
Rubinstein, J. C.; Domanskyi, S.; Sheridan, T. B.; Sanderson, B.; Park, S.; Kaster, J.; Li, H.; Anczukow, O.; Herlyn, M.; Chuang, J. H.
10.1101/2024.02.02.577085 — cancer biology — Posted on 2024-02-05
3940 Time-Informed Dimensionality Reduction for Longitudinal Microbiome Studies
Shi, P.; Martino, C.; Han, R.; Janssen, S.; Buck, G.; Serrano, M.; Owzar, K.; Knight, R.; Shenhav, L.; Zhang, A. R.
10.1101/2023.07.26.550749 — bioinformatics — Posted on 2024-02-05
3943 Single-cell and spatial transcriptomics of the avian embryo tailbud
Mok, G. F.; Turner, S.; Smith, E. L.; Mincarelli, L.; Lister, A.; Lipscombe, J.; Uzun, V.; Haerty, W.; Macaulay, I. C.; Munsterberg, A. E.
10.1101/2024.02.05.578917 — developmental biology — Posted on 2024-02-05
3944 A TBX5-dependent compartment boundary patterns the cardiac interventricular septum
Kathiriya, I. S.; Dominguez, M. H.; Rao, K. S.; Muncie-Vasic, J. M.; Devine, W. P.; Hu, K. M.; Hota, S. K.; Garay, B. I.; Quintero, D.; Goyal, P.; Matthews, M. N.; Thomas, R.; Sukonnik, T.; Miguel-Perez, D.; Winchester, S.; Brower, E. F.; Forjaz, A.; Wu, P.-H.; Wirtz, D.; Kiemen, A. L.; Bruneau, B. G.
10.1101/2024.02.05.578995 — developmental biology — Posted on 2024-02-05
3945 Plasmodium NEK1 coordinates MTOC organisation and kinetochore attachment during rapid mitosis in male gamete formation
Zeeshan, M.; Rashpa, R.; Ferguson, D. J.; Mckeown, G.; Nugmanova, R.; Subodhi, A. K.; Beyeler, R.; Pashley, S. L.; Markus, R.; Brady, D.; Roques, M.; Bottrill, A. R.; Fry, A. M.; Pain, A.; vaughan, s.; Holder, A. A.; Tromer, E. C.; Brochet, M.; Tewari, R.
10.1101/2024.02.05.578160 — cell biology — Posted on 2024-02-05
3947 Spontaneous activity of striatal projection neurons supports maturation of striatal inputs to substantia nigra dopaminergic neurons
Kokinovic, B.; Seja, P.; Donati, A.; Ryazantseva, M.; de Kerchove d'Exaerde, A.; Schiffmann, S. N.; Taira, T.; Molchanova, S. M.
10.1101/2024.01.05.574371 — neuroscience — Posted on 2024-02-05
3949 Species -Shared and -Unique Gyral Peaks on Human and Macaque Brains
Zhang, S.; Zhang, T.; Cao, G.; Zhou, J.; He, Z.; Li, X.; Ren, Y.; Liu, T.; Jiang, X.; Guo, L.; Han, J.; Liu, T.
10.1101/2023.07.26.550760 — neuroscience — Posted on 2024-02-05
3951 Tools and methods for high-throughput single-cell imaging with the mother machine
Thiermann, R.; Sandler, M.; Ahir, G.; Sauls, J. T.; Schroeder, J. W.; Brown, S. D.; Le Treut, G.; Si, F.; Li, D.; Wang, J.; Jun, S.
10.1101/2023.03.27.534286 — systems biology — Posted on 2024-02-05
3954 Tadpoles rely on different sensory modalities for communication throughout development
Butler, J. M.; McKinney, J.; Ludington, S. C.; Mabogunje, M.; Baker, P.; Singh, D.; Edwards, S. V.; O'Connell, L. A.
10.1101/2022.10.18.512729 — developmental biology — Posted on 2024-02-05
3955 Brain and cancer associated binding domain mutations provide insight into CTCF's relationship with chromatin and its ability to act as a chromatin organizer
Do, C.; Jiang, G.; Cova, G.; Katsifis, C. C.; Narducci, D. N.; Yang, J.; Sakellaropoulos, T.; Vidal, R.; Lhoumaud, P.; Fara Regis, F.; Kakabadze, N.; Nora, E. P.; Noyes, M.; Cheng, X.; Hansen, A. S.; Skok, J. A.
10.1101/2024.01.11.575070 — molecular biology — Posted on 2024-02-05
3958 Sensory neurons regulate stimulus-dependent humoral immunity
Aguilar, D.; Zhu, F.; Millet, A.; Millet, N.; Germano, P.; Pisegna, J.; Doherty, T. A.; Swidergall, M.; Jendzjowsky, N.
10.1101/2024.01.04.574231 — immunology — Posted on 2024-02-05
3960 Cyfip2 controls the acoustic startle threshold through FMRP, actin polymerization, and GABAB receptor function.
Deslauriers, J. C.; Ghotkar, R. P.; Russ, L. A.; Jarman, J. M.; Martin, R. M.; Tippett, R. G.; Sumathipala, S. H.; Burton, D. F.; Cole, D. C.; Marsden, K. C.
10.1101/2023.12.22.573054 — neuroscience — Posted on 2024-02-05
3961 Deciphering molecular heterogeneity and dynamics of human hippocampal neural stem cells at different ages and injury states
Yao, J.; Dai, S.; Zhu, R.; Tan, J.; Zhao, Q.; Yin, Y.; Sun, J.; Du, X.; Ge, L.; Xu, J.; Hou, C.; Li, N.; Li, J.; Ji, W.; Zhu, C.; Zhang, R.; Li, T.
10.1101/2023.05.15.540723 — neuroscience — Posted on 2024-02-05
3963 Rejuvenation of Senescent Cells by Low Frequency Ultrasound without Senolysis
Kureel, S. K.; Maroto, R.; Powell, S.; Margadant, F.; Blair, B.; Rasmussen, B.; Sheetz, M.
10.1101/2022.12.08.519320 — physiology — Posted on 2024-02-05
3964 Monocytic fibrocyte-like cell enrichment and myofibroblastic adaptation causes nucleus pulposus fibrosis and associates with disc degeneration severity
Sun, Y.; Peng, Y.; Su, Z.; So, K. K.; Lu, Q.; Lyu, M.; Zuo, J.; Huang, Y.; Guan, Z.; Cheung, K. M.; Zheng, Z.; Zhang, X.; Leung, V. Y.
10.1101/2024.01.16.575808 — physiology — Posted on 2024-02-05
3965 Epigenetic disruption of the RARγ complex impairs its function to bookmark AR enhancer interactions required for enzalutamide sensitivity in prostate cancer
Wani, S. A.; Hussain, S.; Gray, J. S.; Nayak, D.; Tang, H.; Perez, L. M.; Long, M. D.; Siddappa, M.; McCabe, C.; Campbell, L.; Freeman, M. R.; Campbell, M. J.
10.1101/2023.12.15.571947 — cancer biology — Posted on 2024-02-05
3968 Microphase Separation Produces Interfacial Environment within Diblock Biomolecular Condensates
Latham, A. P.; Zhu, L.; Sharon, D. A.; Ye, S.; Willard, A. P.; Zhang, X.; Zhang, B.
10.1101/2023.03.30.534967 — biophysics — Posted on 2024-02-05
3970 Accurate single-molecule spot detection for image-based spatial transcriptomics with weakly supervised deep learning
Laubscher, E.; Wang, X.; Razin, N.; Dougherty, T.; Xu, R.; Ombelets, L.; Pao, E.; Moffitt, J.; Yue, Y.; Van Valen, D. A.
10.1101/2023.09.03.556122 — bioinformatics — Posted on 2024-02-05
3971 Autotrophic adaptive laboratory evolution of the acetogen Clostridium autoethanogenum delivers the gas-fermenting strain LAbrini with superior growth, products, and robustness
Ingelman, H.; Heffernan, J. K.; Harris, A.; Brown, S. D.; Shaikh, K. M.; Yar Saqib, A.; Pinheiro, M. J.; de Lima, L. A.; Rodriguez Martinez, K.; Gonzalez-Garcia, R. A.; Hawkins, G.; Daleiden, J.; Tran, L.; Zeleznik, H.; Jensen, R. O.; Reynoso, V.; Schindel, H.; Jänes, J.; Simpson, S. D.; Köpke, M.; Marcellin, E.; Valgepea, K.
10.1101/2023.01.28.526018 — bioengineering — Posted on 2024-02-05
3972 Redox-dependent condensation and cytoplasmic granulation by human ssDNA binding protein 1 delineate roles in oxidative stress response
Harami, G. M.; Palinkas, J.; Kovacs, Z. J.; Jezso, B.; Tarnok, K.; Harami-Papp, H.; Hegedüs, J.; Mahmudova, L.; Kucsma, N.; Toth, S.; Szakacs, G.; Kovacs, M.
10.1101/2023.07.25.550517 — biochemistry — Posted on 2024-02-05
3976 Sphingolipids regulate the tethering stage of vacuole fusion by affecting membrane fluidity
Zhang, C.; Hurst, L. R.; Gokbayrak, Z. D.; Calderin, J. D.; Hrabak, M. R.; Balutowski, A.; Rivera-Kohr, D. A.; Kazmirchuk, T. D. D.; Brett, C. L.; Fratti, R. A.
10.1101/2020.02.17.953331 — cell biology — Posted on 2024-02-05
3977 Stability of influenza A virus in droplets and aerosols is heightened by the presence of commensal respiratory bacteria.
David, S. C.; Schaub, A.; Terrettaz, C.; Motos, G.; Costa, L.; Nolan, D. S.; Augugliaro, M.; Glas, I.; Pohl, M. O.; Klein, L. K.; Luo, B.; Bluvshtein, N.; Violaki, K.; Hugentobler, W.; Krieger, U. K.; Peter, T.; Stertz, S.; Nenes, A.; Kohn, T.
10.1101/2024.02.05.578881 — microbiology — Posted on 2024-02-05
3979 Complementary cognitive roles for D2-MSNs and D1-MSNs in interval timing
Bruce, R.; Weber, M. A.; Bova, A.; Volkman, R.; Jacobs, C.; Sivakumar, K.; Kim, Y.; Curtu, R.; Narayanan, N.
10.1101/2023.07.25.550569 — neuroscience — Posted on 2024-02-05
3980 Impaired updating of working memory representations in individuals with high BMI: evidence for dopaminergic mechanisms
Herzog, N.; Hartmann, H.; Janssen, L. K.; Kanyamibwa, A.; Waltmann, M.; Kovacs, P.; Deserno, L.; Fallon, S.; Villringer, A.; Horstmann, A.
10.1101/2023.11.03.565528 — neuroscience — Posted on 2024-02-05
3983 In vivo affinity maturation of the HIV-1 Env-binding domain of CD4
Pan, A.; Bailey, C. C.; Ou, T.; Xu, J.; Liu, X.; Hu, B.; Crynen, G.; Skamangas, N.; Bronkema, N.; Tran, M.; Mu, H.; Zhang, X.; Yin, Y.; Alpert, M. D.; He, W.; Farzan, M.
10.1101/2024.02.03.578630 — bioengineering — Posted on 2024-02-05
3986 Mechanism of degrader-targeted protein ubiquitinability
Crowe, C.; Nakasone, M.; Chandler, S.; Tatham, M. H.; Makukhin, N.; Hay, R. T.; Ciulli, A.
10.1101/2024.02.05.578957 — biochemistry — Posted on 2024-02-05
3988 Nanopore-based DNA long-read sequencing analysis of the aged human brain
Ramirez, P.; Sun, W.; Kazempour Dehkordi, S.; Zare, H.; Fongang, B.; Bieniek, K. F.; Frost, B.
10.1101/2024.02.01.578450 — genomics — Posted on 2024-02-05
3989 Characterizing and addressing error modes to improve sequencing accuracy
Kruglyak, S.; Altomare, A.; Ambroso, M.; Dien, V.; Lajoie, B. R.; Wiseman, K. N.; Levy, S. E.; Kellinger, M.
10.1101/2024.02.01.578321 — genomics — Posted on 2024-02-05
3990 Chromosome-scale genome assembly of the rough periwinkle Littorina saxatilis
De Jode, A.; Faria, R.; Formenti, G.; Sims, Y.; Smith, T.; Tracey, A.; Wood, J. M. D.; Zagrodzka, Z. B.; Johannesson, K.; Butlin, R. K.; Leder, E. H.
10.1101/2024.02.01.578480 — genomics — Posted on 2024-02-05
3994 NEAT1 promotes genome stability via m6A methylation-dependent regulation of CHD4
Mamontova, V.; Trifault, B.; Gribling-Burrer, A.-S.; Bohn, P.; Preckwinkel, P.; Schmitz, W.; Gallant, P.; Papadopoulos, D.; Eilers, M.; Gutschner, T.; Smyth, R. P.; Burger, K.
10.1101/2024.02.05.578920 — molecular biology — Posted on 2024-02-05
3995 TAF2 condensation in nuclear speckles links basal transcription factor TFIID to RNA splicing
Bhuiyan, T.; Mendoza Sanchez, P. K.; Arecco, N.; Kim, J.; Nizamuddin, S.; Prunotto, A.; Tekman, M.; Biniossek, M. L.; Koidl, S.; Hugel, T.; Arnold, S. J.
10.1101/2024.02.05.578926 — molecular biology — Posted on 2024-02-05
3998 Optimal Performance Objectives in the Highly Conserved Bone Morphogenetic Protein Signaling Pathway
Shaikh, R.; Larson, N. J.; Hanjaya-Putra, D.; Zartman, J. J.; Umulis, D. M.; Li, L.; Reeves, G. T.
10.1101/2024.02.01.578451 — systems biology — Posted on 2024-02-05
3999 Spotiflow: accurate and efficient spot detection for imaging-based spatial transcriptomics with stereographic flow regression
Dominguez Mantes, A.; Herrera, A.; Khven, I.; Schlaeppi, A.; Kyriacou, E.; Tsissios, G.; Aztekin, C.; Ligner, J.; La Manno, G.; Weigert, M.
10.1101/2024.02.01.578426 — bioinformatics — Posted on 2024-02-05
4002 Sparse CBX2 nucleates many Polycomb proteins to promote facultative heterochromatinization of Polycomb target genes
Ingersoll, S.; Trouth, A.; Luo, X.; Espinoza, A.; Wen, J.; Tucker, J.; Astatike, K.; Phiel, C. J.; Kutateladze, T. G.; WU, T. P.; Ramachandran, S.; Ren, X.
10.1101/2024.02.05.578969 — molecular biology — Posted on 2024-02-05
4003 XBB.1.5 monovalent booster improves antibody binding and neutralization against emerging SARS-CoV-2 Omicron variants
Jain, S.; Kumar, S.; Lai, L.; Linderman, S.; Malik, A. A.; Ellis, M. L.; Godbole, S.; Solis, D.; Sahoo, M. K.; Bechnak, K.; Paredes, I.; Tanios, R.; Kazzi, B.; Dib, S. M.; Litvack, M. B.; Wimalsena, S. T.; Ciric, C.; Rostad, C.; West, R.; Teng, I.-T.; Wang, D.; Kwong, P. D.; Rouphael, N.; Pinsky, B. A.; Douek, D. C.; Wrammert, J.; Moreno, A.; Suthar, M. S.
10.1101/2024.02.03.578771 — immunology — Posted on 2024-02-05
4004 Capture and Release of Minke Whales Offers New Research Opportunities Including Measurements of Mysticete Hearing
Kleivane, L.; Kvadsheim, P. H.; Vinje, A. V. P.; Mulsow, J.; Olberg, R. A.; Teilmann, J.; Harms, C.; Houser, D.
10.1101/2024.02.02.577929 — physiology — Posted on 2024-02-05
4005 A Simple and Scalable Zebrafish Model of Sonic Hedgehog Medulloblastoma
Casey, M. J.; Chan, P. P.; Li, Q.; Jette, C. A.; Kohler, M.; Myers, B. R.; Stewart, R. A.
10.1101/2024.02.03.577834 — cancer biology — Posted on 2024-02-05
4009 MAGIC matrices: freeform bioprinting materials to support complex and reproducible organoid morphogenesis
Graham, A. J.; Khoo, M. W. L.; Srivastava, V.; Viragova, S.; Parekh, K.; Morley, C. D.; Bird, M.; Lebel, P.; Kumar, S.; Klein, O. D.; Gomez-Sjoberg, R.; Gartner, Z. J.
10.1101/2024.02.01.578324 — bioengineering — Posted on 2024-02-05
4010 Functional 3'-UTR Variants Identify Regulatory Mechanisms Impacting Alcohol Use Disorder and Related Traits
Chen, A. B.; Yu, X.; Thapa, K. S.; Gao, H.; Reiter, J. L.; Xuei, X.; Tsai, A. P.; Landreth, G. E.; Lai, D.; Wang, Y.; Foroud, T. M.; Tischfield, J. A.; Edenberg, H. J.; Liu, Y.
10.1101/2024.01.31.578270 — genomics — Posted on 2024-02-05
4012 Before and after delisting: population dynamics of North Atlantic humpback whales over two decades in the Gulf of Maine
Robbins, J.; Berube, M.; Clapham, P. J.; Mattila, D. K.; Palsboll, P. J.; Asmutis-Silvia, R.; Hill, A.; Howes, L. J.; Landry, S.; Lonergan, S.; Schulte, D.; Tackaberry, J. E.; Weinrich, M. T.; Pace, R. M.
10.1101/2024.02.04.577870 — ecology — Posted on 2024-02-05
4013 Cryosectioning-enabled super-resolution microscopy for studying nuclear architecture at the single protein level
Stein, J.; Ericsson, M.; Nofal, M.; Magni, L.; Aufmkolk, S.; McMillan, R. B.; Breimann, L.; Herlihy, C. P.; Lee, S. D.; Willemin, A.; Wohlmann, J.; Arguedas-Jimenez, L.; Yin, P.; Pombo, A.; Church, G. M.; Wu, C.-t.
10.1101/2024.02.05.576943 — cell biology — Posted on 2024-02-05
4018 Prolonged airway explant culture enables study of health, disease, and viral pathogenesis
Lee-Ferris, R. E.; Okuda, K.; Galiger, J. R.; Schworer, S. A.; Rogers, T. D.; Dang, H.; Gilmore, R.; Edwards, C.; Nakano, S.; Cawley, A. M.; Pickles, R. J.; Gallant, S. C.; Crisci, E.; Rivier, L.; Hagood, J. S.; O'Neal, W. K.; Baric, R. S.; Grubb, B. R.; Boucher, R. C.; Randell, S. H.
10.1101/2024.02.03.578756 — bioengineering — Posted on 2024-02-05
4019 Enzyme Bioink for the 3D Printing of Biocatalytic Materials
Altevogt, L. A.; Sheikh, R. H.; Molley, T. G.; Yong, J.; Liang, K.; Spicer, P.; Kilian, K. A.; Wich, P. R.
10.1101/2024.02.04.577699 — bioengineering — Posted on 2024-02-05
4021 Genomic insights into photosymbiotic evolution in Tridacna squamosa
Zhang, Y.; Mao, F.; Li, Y.; Wong, N.-K.; Bao, Y.; Dai, H.; Sun, J.; Yi, W.; Xiao, S.; Xiang, Z.; Li, J.; Zhang, Y.; Xia, X.; Zhang, L.; Zhou, H.; Yu, Z.
10.1101/2024.02.04.577604 — evolutionary biology — Posted on 2024-02-05
4024 A POLR3B-variant reveals a Pol III transcriptome response dependent on La protein/SSB
Mattijssen, S.; Kerkhofs, K.; Stephen, J.; Yang, A.; Han, C. G.; Tadafumi, Y.; Iben, J. R.; Mishra, S.; Sakhawala, R. M.; Ranjan, A.; Gowda, M.; Gahl, W. A.; Gu, S.; Malicdan, M. C.; Maraia, R. J.
10.1101/2024.02.05.577363 — molecular biology — Posted on 2024-02-05
4025 Unprocessed Genomic Uracil as a Source of DNA Replication Stress in Cancer Cells
Saxena, S.; Patel, P. S.; Nabel, C. S.; Kawale, A. S.; Crosby, C. R.; Vander Heiden, M. G.; Hata, A. N.; Zou, L.
10.1101/2024.02.05.578390 — molecular biology — Posted on 2024-02-05
4026 Tamm-Horsfall protein augments neutrophil NETosis during urinary tract infection
Mercado-Evans, V.; Chew, C.; Serchejian, C.; Saltzman, A.; Mejia, M.; Zulk, J.; Cornax, I.; Nizet, V.; Patras, K.
10.1101/2024.02.01.578501 — immunology — Posted on 2024-02-05
4030 BiaPy: A unified framework for versatile bioimage analysis with deep learning
Franco-Barranco, D.; Andres-San Roman, J. A.; Hidalgo-Cenalmor, I.; Backova, L.; Gonzalez-Marfil, A.; Caporal, C.; Chessel, A.; Gomez-Galvez, P.; Escudero, L. M.; Wei, D.; Munoz-Barrutia, A.; Arganda-Carreras, I.
10.1101/2024.02.03.576026 — bioinformatics — Posted on 2024-02-05
4032 Nix coordinates nuclear calcium signaling to modulate the muscle phenotype.
Field, J. T.; Chapman, D.; Ghavami, S.; West, A. R.; Saleem, A.; Kindrachuk, J.; Triggs-Raine, B.; Gordon, J. W.
10.1101/2023.03.18.532760 — cell biology — Posted on 2024-02-05
4035 In-vivo distributed multicellular control of gene expression in microbial consortia
Salzano, D.; Shannon, B.; Grierson, C.; Marucci, L.; Savery, N.; di Bernardo, M.
10.1101/2023.11.13.566807 — synthetic biology — Posted on 2024-02-05
4037 APCalign: an R package workflow and app for aligning and updating flora names to the Australian Plant Census
Wenk, E. H.; Cornwell, W.; Fuchs, A.; Kar, F.; Monro, A.; Sauquet, H.; Stephens, R. E.; Falster, D. S.
10.1101/2024.02.02.578715 — plant biology — Posted on 2024-02-05
4040 Medicago truncatula ABCG40 is a cytokinin importer that negatively regulates lateral root density and nodule number
Jamruszka, T.; Banasiak, J.; Pawela, A.; Jarzyniak, K.; Xia, J.; Biala, W.; Plackova, L.; Tsering, T.; Iacobini, F. R.; Novak, O.; Geisler, M. M.; Jasinski, M.
10.1101/2022.11.10.516000 — plant biology — Posted on 2024-02-05
4043 Transposition of HOPPLA in siRNA-deficient plants suggests a limited effect of the environment on retrotransposon mobility in Brachypodium distachyon
Thieme, M.; Minadakis, N.; Himber, C.; Keller, B.; Xu, W.; rutowicz, K.; Matteoli, C.; Boehrer, M.; Rymen, B.; Laudencia-Chingcuanco, D.; Vogel, J. P.; Sibout, R.; Stritt, C.; Blevins, T.; Roulin, A. C.
10.1101/2023.09.25.559196 — genomics — Posted on 2024-02-05
4047 A lactate-dependent shift of glycolysis mediates synaptic and cognitive processes
Fernandez-Moncada, I.; Lavanco, G.; B. Fundazuri, U.; Bollmohr, N.; Mountadem, S.; Hachaguer, P.; Julio-Kalajzic, F.; Gisquet, D.; Dalla Tor, T.; Serrat, R.; Bellocchio, L.; Cannich, A.; Fortunato-Marsol, B.; Nasu, Y.; Campbell, R. E.; Drago, F.; Cannizzaro, C.; Bouzier-Sore, A.-K.; Ferreira, G.; Pellerin, L.; Bolanos, J. P.; Bonvento, G.; Barros, L. F.; Oliet, S. H. R.; Panatier, A.; Marsicano, G.
10.1101/2023.03.15.532748 — neuroscience — Posted on 2024-02-05
4057 Prior probability cues bias sensory encoding with increasing task exposure
Walsh, K.; McGovern, D. P.; Dully, J.; Kelly, S. P.; O'Connell, R. G.
10.1101/2023.07.15.549123 — neuroscience — Posted on 2024-02-05
4058 Inflammation and autophagy dysfunction in metachromatic leukodystrophy: a central role for mTOR?
Catchpole, Z.; Hartanto, A. E.; Kataura, T.; Palmowski, P.; Porter, A.; Ulicna, K.; McFarland, R.; Pyle, A.; Taylor, R.; Harris, K. S.; Korolchuk, V. I.; Erskine, D.
10.1101/2023.09.14.557720 — neuroscience — Posted on 2024-02-05
4059 Local translation is engaged to sustain synaptic function in impaired Wallerian degeneration
Paglione, M.; Restivo, L.; Zakhia, S.; Llobet Rosell, A.; Terenzio, M.; Neukomm, L. J.
10.1101/2023.08.18.553870 — neuroscience — Posted on 2024-02-05
4061 Pharmacological control of CAR T cells through CRISPR-driven rapamycin resistance
Levesque, S.; Carleton, G.; Duque, V.; Goupil, C.; Fiset, J.-P.; Villeneuve, S.; Normandeau, E.; Morin, G.; Dumont, N.; Nelson, B. H.; Laganiere, J.; Boyle, B.; Lum, J. J.; Doyon, Y.
10.1101/2023.09.14.557485 — cancer biology — Posted on 2024-02-05
4063 Depth-dependent scaling of axial distances in light microscopy
Loginov, S.; Boltje, D.; Hensgens, M. N. F.; Hoogenboom, J. P.; van der Wee, E.
10.1101/2024.01.31.578242 — biophysics — Posted on 2024-02-05
4066 Architecture of intact mammalian pyruvate dehydrogenase complex revealed by in-situ structural analysis
Wang, C.; Ma, C.; Chang, S.; Wu, H.; Yan, C.; Chen, J.; Wu, Y.; An, S.; Xu, J.; Han, Q.; Jiang, Y.; Jiang, Z.; Gao, H.; Zhang, X.; Chang, Y.
10.1101/2024.02.01.578502 — cell biology — Posted on 2024-02-05
4068 Spatiotemporal Clusters of ERK Activity Coordinate Cytokine-induced Inflammatory Responses in Human Airway Epithelial Cells
DeCuzzi, N. L.; Oberbauer, D.; Chmiel, K. J.; Pargett, M.; Ferguson, J. M. A.; Murphy, D.; Zeki, A. A.; Albeck, J. G.
10.1101/2024.02.03.578773 — cell biology — Posted on 2024-02-05
4071 Visual stimulation drives retinotopic acetylcholine release in the mouse visual cortex
Knudstrup, S. G.; Martinez-Reyes, C.; Rauscher, B.; Doran, P. R.; Fomin-Thunemann, N.; Kılıc, K.; Jiang, J. X.; Devor, A.; Thunemann, M.; Gavornik, J. P.
10.1101/2024.02.04.578821 — neuroscience — Posted on 2024-02-05
4072 A call for a unified and multimodal definition of cellular identity in the enteric nervous system
Majd, H.; Cesiulis, A.; Samuel, R. M.; Richter, M. N.; Elder, N.; Guyer, R. A.; Hao, M.; Stamp, L.; Goldstein, A.; Fattahi, F.
10.1101/2024.01.15.575794 — neuroscience — Posted on 2024-02-05
4073 Inner hair cell synapse density influences auditory processing
Ji, L.; Borges, B. C.; Martel, D. T.; Wu, C.; Liberman, M. C.; Shore, S. E.; Corfas, G.
10.1101/2022.05.02.490340 — neuroscience — Posted on 2024-02-05
4075 Oxidative stress induces release of mitochondrial DNA into the extracellular space in human placental villous trophoblast BeWo cells
Gardner, J. J.; Cushen, S. C.; Silva, R. d. N.; Bradshaw, J. L.; Hula, N.; Gorham, I. K.; Tucker, S. M.; Zhou, Z.; Cunningham, R. L.; Phillips, N. R.; Goulopoulou, S.
10.1101/2024.02.02.578433 — cell biology — Posted on 2024-02-04
4076 A genome-wide screen links peroxisome regulation with Wnt signaling through RNF146 and tankyrase
Vu, J. T.; Tavasoli, K. U.; Mandjikian, L.; Sheedy, C. J.; Bacal, J.; Morrissey, M. A.; Richardson, C. D.; Gardner, B. M.
10.1101/2024.02.02.578667 — cell biology — Posted on 2024-02-04
4078 SMCHD1 activates the expression of genes required for the expansion of human myoblasts
Wong, M. M.-K.; Gardner, E.; Megeney, L. A.; Emerson, C. P.; Gabellini, D. P.; Dilworth, J.
10.1101/2024.02.04.578809 — cell biology — Posted on 2024-02-04
4079 Microgroove substrates unveil topography-driven, dynamic 3D nuclear deformations
Leclech, C.; Roellinger, B.; Frederick, J.; Mamchaoui, K.; Coirault, C.; Barakat, A. I.
10.1101/2024.02.02.578638 — cell biology — Posted on 2024-02-04
4080 BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III
Chen, B.; Lynn-Nguyen, T. M.; Jadhav, P.; Halligan, B. S.; Rossiter, N. J.; Guerra, R. M.; Koshkin, S.; Koo, I.; Morlacchi, P.; Hanna, D. A.; Lin, J.; Banerjee, R.; Pagliarini, D.; Patterson, A. D.; Mosalaganti, S.; Sexton, J.; Cali, T.; Lyssiotis, C. A.; Shah, Y. M.
10.1101/2024.02.02.578646 — cell biology — Posted on 2024-02-04
4082 Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction and leads to increased glucose uptake in tafazzin-deficient cells
Liang, Z.; Ralph-Epps, T.; Schmidtke, M. W.; Lazcano, P.; Denis, S. W.; Balazova, M.; Chakkour, M.; Hazime, S.; Ren, M.; Schlame, M.; Houtkooper, R.; Greenberg, M.
10.1101/2024.02.03.578755 — cell biology — Posted on 2024-02-04
4083 Human Amniotic Epithelial Cells Promote Chx10-/Pax6+ Muller Glia Subpopulation Reprogramming into Photoreceptor-like Cells
Gao, H.; Yin, Z.; Huang, X.; Zeng, Y.; Zou, T.; A, L.; Zhe, C.; Cheng, X.; Ge, L.; Kang, J.; Lin, X.; Gong, H.; Xie, J.; Fan, X.; xu, H.
10.1101/2024.02.01.578388 — cell biology — Posted on 2024-02-04
4084 TIAM1 signaling drives prostatic budding and branching phenotypes and is a potential therapeutic target for BPH
Khedmatgozar, H.; Dutta, S.; Dominguez, M.; Latour, D.; Johnson, M.; Fokar, M.; Warraich, I.; DeRiese, W.; Haynes, A.; Matusik, R. J.; Brandi, L.; Nandana, S.; Tripathi, M.
10.1101/2024.02.02.578055 — cell biology — Posted on 2024-02-05
4087 High Shear Stress Reduces ERG Causing Endothelial-Mesenchymal Transition and Pulmonary Arterial Hypertension
Shinohara, T.; Moonen, J.-R. A. J.; Chun, Y. H.; Lee-Yow, Y. C.; Okamura, K.; Szafron, J. M.; Kaplan, J.; Cao, A.; Wang, L.; Taylor, S.; Isobe, S.; Dong, M.; Yang, W.; Guo, K.; Franco, B. D.; Pacharinsak, C.; Pisani, L. J.; Saitoh, S.; Mitani, Y.; Marsden, A. L.; Engreitz, J.; Korbelin, J.; Rabinovitch, M.
10.1101/2024.02.02.578526 — cell biology — Posted on 2024-02-05
4089 Endothelial PHD2 deficiency induces apoptosis resistance and inflammation via AKT activation and AIP1 loss independent of HIF2α
Wang, S.; Awad, K. S.; Chen, L.-Y.; Siddique, M. A. H.; Ferreyra, G. A.; Wang, C. L.; Joseph, T.; Yu, Z.-X.; Takeda, K.; Demirkale, C. Y.; Zhao, Y.; Elinoff, J. M.; Danner, R. L.
10.1101/2024.02.01.578286 — cell biology — Posted on 2024-02-05
4090 Hypoxia and TNF-alpha modulate extracellular vesicle release from human induced pluripotent stem cell-derived cardiomyocytes
Viola, M.; Bebelman, M. P.; Maas, R. G. C.; Verweij, F. J.; Seinen, C. S.; de Jager, S. C. A.; Vader, P.; Pegtel, D. M.; Sluijter, J. P. G.
10.1101/2024.02.01.578434 — cell biology — Posted on 2024-02-05
4091 OPA1 and disease-causing mutants perturb mitochondrial nucleoid distribution
Macuada, J.; Molina-Riquelme, I.; Vidal, G.; Perez-Bravo, N.; Vasquez-Trincado, C.; Aedo, G.; Lagos, D.; Horvath, R.; Rudge, T. J.; Cartes-Saavedra, B.; Eisner, V.
10.1101/2024.02.01.578418 — cell biology — Posted on 2024-02-05
4092 Modeling Normal Mouse Uterine Contraction and Placental Perfusion with Non- invasive Longitudinal Dynamic Contrast Enhancement MRI
Cortes, D. R. E.; Stapleton, M. C.; Schwab, K. E.; West, D.; Coulson, N. W.; O'Donnell, M. G.; Powers, R. W.; Wu, Y.
10.1101/2024.01.31.577398 — systems biology — Posted on 2024-02-04
4093 Combining systems and synthetic biology for in vivo enzymology
Castano-Cerezo, S.; Chamas, A.; Kulyk, H.; Treitz, C.; Bellvert, F.; Tholey, A.; Galeote, V.; Camarasa, C.; Heux, S.; Garcia-Alles, L. F.; Millard, P.; Truan, G.
10.1101/2024.02.02.578620 — systems biology — Posted on 2024-02-04
4094 Germinal center BCR maturation in appendicitis reveals a role for antigen-specific adaptive immune responses during disease
Stewart, E.; Taghvaei, Z.; Leon, C.; Shapiro, J.; Zhu, L.; Alpert, L.; Turaga, K.; Roy Chowdhury, R.
10.1101/2024.01.31.578312 — immunology — Posted on 2024-02-04
4099 Structure-guided engineering of a fast genetically encoded sensor for real-time H2O2 monitoring.
Lee, J. D.; Won, W.; Kimball, K.; Wang, Y.; Yeboah, F.; Evitts, K.; Neiswanger, C.; Schattauer, S.; Rappleye, M.; Bremner, S. B.; Chun, C.; Smith, N.; Mack, D. L.; Young, J. E.; Lee, C. J.; Chavkin, C.; Berndt, A.
10.1101/2024.01.31.578117 — bioengineering — Posted on 2024-02-04
4100 A programmable arthritis-specific receptor for guided articular cartilage regenerative medicine
Walton, B. L.; Shattuck-Brandt, R.; Hamann, C. A.; Tung, V. W.; Colazo, J. M.; Brand, D. D.; Hasty, K. A.; Duvall, C. L.; Brunger, J. M.
10.1101/2024.01.31.578281 — bioengineering — Posted on 2024-02-04
4102 An ECM scaffold combined with a compliant 3D printed spring-shaped reinforcement for cartilage engineering applications
Solorzano Requejo, W.; Limones Ahijon, B.; Corchado, C.; Llorca, J.; Diaz Lantada, A.; Patterson, J.; Diaz-Payno, P. J.
10.1101/2024.01.31.575642 — bioengineering — Posted on 2024-02-04
4103 Pesticide chemical leads inhibiting protein-protein interactions
Ben Shushan, R. S.; Cohen, E.; Ben Naim, N.; Amram, E.; Gressel, J.; Peleg, D.; Dotan, N.; Bloch, I.; Gal, M.
10.1101/2024.02.03.578754 — biochemistry — Posted on 2024-02-04
4106 Pyruvate metabolism dictates fibroblast sensitivity to GLS1 inhibition during fibrogenesis
Contento, G.; Wilson, J.-A. A.; Selvarajah, B.; Plate, M.; Guillotin, D.; Morales, V.; Trevisani, M.; Pitozzi, V.; Bianchi, K.; Chambers, R. C.
10.1101/2024.01.30.577965 — cell biology — Posted on 2024-02-04
4107 Unbiased, Cell-free Profiling of Single Influenza Genomes at High-throughput
Cowell, T. W.; Puryear, W.; Chen, C.-L.; Ding, R.; Runstadler, J.; Han, H.-S.
10.1101/2024.02.03.578479 — molecular biology — Posted on 2024-02-04
4108 A neutral process of genome reduction in marine bacterioplankton
Wang, X.; Xie, M.; Ho, K. E. Y. K.; Sun, Y.; Chu, X.; Zhang, S.; Ringel, V.; Wang, H.; Zhang, X.-H.; Shao, Z.; Zhao, Y.; Brinkhoff, T.; Petersen, J.; Wagner-Döbler, I.; Luo, H.
10.1101/2024.02.04.578831 — microbiology — Posted on 2024-02-04
4109 Genomic and environmental controls on Castellaniella biogeography in an anthropogenically disturbed subsurface
Goff, J. L.; Szink, E. G.; Durrence, K. L.; Lui, L. M.; Nielsen, T. N.; Kuehl, J. V.; Hunt, K. A.; Chandonia, J.-M.; Huang, J.; Thorgersen, M. P.; Poole, F. L.; Stahl, D. A.; Chakraborty, R.; Deutschbauer, A. M.; Arkin, A. P.; Adams, M. W. W.
10.1101/2024.02.03.578758 — microbiology — Posted on 2024-02-04
4110 Variant Surface Protein GP60 Contributes to Host Infectivity of Cryptosporidium parvum
Li, M.; Yang, F.; Hou, T.; Gong, X.; Li, N.; Sibley, L. D.; Feng, Y.; Xiao, L.; Guo, Y.
10.1101/2024.02.04.578776 — microbiology — Posted on 2024-02-04
4111 Time resolved multi-omics reveals diverse metabolic strategies of Salmonella during diet-induced inflammation
Kokkinias, K.; Sabag-Daigle, A.; Kim, Y.; Leleiwi, I.; Shaffer, M.; Kevorkian, R.; Daly, R. A.; Wysocki, V. H.; Borton, M. A.; Ahmer, B. M. M.; Wrighton, K. C.
10.1101/2024.02.03.578763 — microbiology — Posted on 2024-02-04
4112 Activation loop phosphorylation and cGMP saturation of PKG regulate egress of malaria parasites.
Koussis, K.; Haase, S.; Withers-Martinez, C.; Flynn, H. R.; Kunzelmann, S.; Christodoulou, E.; Ibrahim, F.; Skehel, M.; Baker, D. A.; Blackman, M. J.
10.1101/2024.02.04.578801 — microbiology — Posted on 2024-02-04
4115 Matrix confinement modulates 3D spheroid sorting and burst-like collective migration
Cai, G.; Li, X.; Lin, S.-S.; Chen, S. J.; Rodgers, N. C.; Koning, K. M.; Bi, D.; Liu, A. P.
10.1101/2023.07.23.549940 — biophysics — Posted on 2024-02-04
4118 Tunable Macroscopic Alignment of Self-Assembling Peptide Nanofibers
Farsheed, A. C.; Zevallos-Delgado, C.; Yu, L. T.; Saeidifard, S.; Swain, J. W. R.; Makhoul, J. T.; Thomas, A. J.; Cole, C. C.; Garcia Huitron, E.; Grande-Allen, K. J.; Singh, M.; Larin, K. V.; Hartgerink, J. D.
10.1101/2024.02.02.578651 — bioengineering — Posted on 2024-02-04
4119 Focused Ultrasound Blood-Brain Barrier Opening Arrests the Growth and Formation of Cerebral Cavernous Malformations
Fisher, D. G.; Sharifi, K. A.; Shah, I. M.; Gorick, C. M.; Breza, V. R.; Debski, A. C.; Hoch, M.; Cruz, T.; Samuels, J. D.; Sheehan, J.; Schlesinger, D.; Moore, D.; Lukens, J. R.; Tvrdik, P.; Miller, G. W.; Price, R. J.
10.1101/2024.01.31.577810 — bioengineering — Posted on 2024-02-04
4120 Selective inhibitors of the Aurora A-TPX2 protein-protein interaction exhibit in vivo efficacy as targeted anti-mitotic agents
Stockwell, S. R.; Scott, D. E.; Fischer, G.; Guarino, E.; Rooney, T. P. C.; Fang, T.-S.; Moschetti, T.; Srinivasan, R.; Alza, E.; Asteian, A.; Dagostin, C.; Alcaide, A.; Rocaboy, M.; Blaszczyk, B.; Higueruelo, A.; Wang, X.; Rossmann, M.; Perrior, T. R.; Blundell, T. L.; Spring, D. R.; McKenzie, G.; Abell, C.; Skidmore, J.; Venkitaraman, A. R.; Hyvönen, M.
10.1101/2023.03.22.533679 — biochemistry — Posted on 2024-02-04
4121 DNA-dependent phase separation by human SSB2 (NABP1/OBFC2A) protein points to adaptations to eukaryotic genome repair processes
Kovacs, Z. J.; Harami, G. M.; Palinkas, J.; Kuljanishvili, N.; Hegedüs, J.; Harami-Papp, H.; Mahmudova, L.; Khamisi, L.; Szakacs, G.; Kovacs, M.
10.1101/2023.09.15.557979 — biochemistry — Posted on 2024-02-04
4122 Functional Analysis of the Zinc Finger Modules of the S. cerevisiae Splicing Factor Luc7
Carrocci, T. J.; DeMario, S. M.; He, K.; Zeps, N. J.; Harkner, C.; CHANFREAU, G. F.; Hoskins, A.
10.1101/2024.02.04.578419 — biochemistry — Posted on 2024-02-04
4126 Bundle Analytics based Data Harmonization for Multi-Site Diffusion MRI Tractometry
Chandio, B. Q.; Villalon-Reina, J. E.; Nir, T. M.; Thomopoulos, S. I.; Feng, Y. W.; Benavidez, S.; Jahanshad, N.; Harezlak, J.; Garyfallidis, E.; Thompson, P. M.
10.1101/2024.02.03.578764 — neuroscience — Posted on 2024-02-04
4127 Limb, not touch location, is coded in 3D space
Heed, T.; Burbach, J.; Roedenbeck, N.; Habets, B.; Fuchs, X.
10.1101/2024.02.01.578364 — neuroscience — Posted on 2024-02-04
4129 Multiple Loci for Foveolar Vision in Macaque Monkey
Qian, M.; Wang, J.; Gao, Y.; Chen, M.; Liu, Y.; Zhou, D.; Lv, H.; Zhang, X.; Hu, J.; Roe, A. W.
10.1101/2024.02.01.578387 — neuroscience — Posted on 2024-02-04
4131 Neonatal Amygdala Mean Diffusivity: A Potential Predictor of Emotional Face Perception
Hashempour, N.; Tuulari, J. J.; Merisaari, H.; Lewis, J. D.; Häikiö, T.; Scheinin, N. M.; Nolvi, S.; Korja, R.; Karlsson, L.; Karlsson, H.; Kataja, E.-L.
10.1101/2024.02.04.578788 — neuroscience — Posted on 2024-02-04
4133 Disrupted mitochondrial response to nutrients is a presymptomatic event in the cortex of the APPSAA knock-in mouse model of Alzheimer disease
Norambuena, A.; Sagar, V. K.; Wang, Z.; Raut, P.; Feng, Z.; Wallrabe, H.; Pardo, E.; Kim, T.; Alam, S. R.; Hu, S.; Periasamy, A.; Bloom, G. S.
10.1101/2024.02.02.578668 — neuroscience — Posted on 2024-02-04
4134 Altered nuclear envelope homeostasis is a key pathogenic event in C9ORF72-linked ALS/FTD
Sirtori, R.; Gregoire, M. J.; Collins, A.; Santangelo, S.; Chatragadda, B.; Cullen, R.; Ratti, A.; Fallini, C.
10.1101/2024.02.01.578318 — neuroscience — Posted on 2024-02-04
4140 Chronic IL-1-induced DNA double-strand break response in hippocampal neurons drives cognitive deficits
Belloy, M.; Schmitt, B. A.; Marty, F. H.; Paut, C.; Bassot-Parra, E.; Aida, A.; Alis, M.; Ecalard, R.; Boursereau, R.; Gonzalez-Dunia, D.; Blanchard, N.; Suberbielle, E.
10.1101/2024.02.03.578747 — animal behavior and cognition — Posted on 2024-02-04
4144 Suppression of ERK signalling promotes pluripotent epiblast in the human blastocyst
Simon, C. S.; McCarthy, A.; Woods, L.; Staneva, D.; Huang, Q.; Linneberg-Agerholm, M.; Faulkner, A.; Papathanasiou, A.; Elder, K.; Snell, P.; Christie, L.; Garcia, P.; Shaikly, V.; Taranissi, M.; Choudhary, M.; Herbert, M.; Brickman, J. M.; Niakan, K. K.
10.1101/2024.02.01.578414 — developmental biology — Posted on 2024-02-04
4145 Direct modulation of TRPM8 ion channels by rapamycin and analog macrolide immunosuppressants
Toth, B. I.; Bazeli, B.; Janssens, A.; Lisztes, E.; Racsko, M.; Kelemen, B.; Herczeg, M.; Nagy, T. M.; E. Köver, K.; Mitra, A.; Borics, A.; Biro, T.; Voets, T.
10.1101/2024.02.01.578392 — neuroscience — Posted on 2024-02-04
4147 Rapid Invisible Frequency Tagging (RIFT) in a novel setup with EEG
Arora, K.; Gayet, S.; Kenemans, J. L.; Van der Stigchel, S.; Chota, S.
10.1101/2024.02.01.578462 — neuroscience — Posted on 2024-02-04
4148 Aperiodic and Hurst EEG exponents across early human brain development: a systematic review
Stanyard, R. A.; Mason, D.; Ellis, C.; Dickson, H.; Short, R.; Batalle, D.; Arichi, T.
10.1101/2024.02.02.578622 — neuroscience — Posted on 2024-02-04
4150 Distractor suppression operates exclusively in retinotopic coordinates
Ilksoy, Y. A.; van Moorselaar, D.; Wang, B.; Los, S. A.; Theeuwes, J.
10.1101/2024.02.01.578407 — neuroscience — Posted on 2024-02-04
4152 Cell lipotypes localization in brain by mass spectrometry imaging
Martinez-Gardeazabal, J.; Moreno-Rodriguez, M.; Llorente-Ovejero, A.; Gonzalez de San Roman, E.; Lombardero, L.; Bengoetxea de Tena, I.; Sustacha, J.; Matute, C.; Manuel, I.; Bonifazi, P.; Rodriguez-Puertas, R.
10.1101/2024.02.02.578599 — neuroscience — Posted on 2024-02-04
4154 Solaris: a panel of bright and sensitive hybrid voltage indicators for imaging membrane potential in cultured neurons
Yang, J.; Zhu, S.; Yang, L.; Peng, L.; Han, Y.; Hayward, R. F.; Park, P.; Hu, D.; Cohen, A. E.; Zou, P.
10.1101/2024.02.02.578569 — neuroscience — Posted on 2024-02-04
4157 TMEM63B functions as a mammalian thirst receptor
Zou, W.; Chen, X.; Ruan, J.; Deng, S.; Zhan, W.; Wang, J.; Liu, Z.; Yan, Z.
10.1101/2024.02.01.578339 — neuroscience — Posted on 2024-02-04
4164 Attractor-like circuits improve visual decoding and behavior in zebrafish
Privat, M.; Hansen, E.; Pietri, T.; Marachlian, E.; Uribe, A.; Duchemin, A.; Candat, v.; Nourin, S.; Sumbre, G.
10.1101/2024.02.03.578596 — neuroscience — Posted on 2024-02-04
4165 Transcriptional programs mediating neuronal toxicity and altered glial-neuronal signaling in a Drosophila knock-in tauopathy model
Bukhari, H.; Nithianandam, V.; Battaglia, R.; Cicalo, A.; Sarkar, S.; Comjean, A.; Hu, Y.; Leventhal, M.; Dong, X.; Feany, M.
10.1101/2024.02.02.578624 — neuroscience — Posted on 2024-02-04
4168 Pharmacological Enhancement of Adult Hippocampal Neurogenesis Improves Behavioral Pattern Separation in Young and Aged Mice
Chang, W.-l.; Tegang, K.; Samuels, B. A.; Saxe, M.; Wichmann, J.; David, D. J.; David, I. M.; Augustin, A.; Fischer, H.; Golling, S.; Lamerz, J.; Roth, D.; Graf, M.; Zoffmann, S.; Santarelli, L.; Jagasia, R.; Hen, R.
10.1101/2024.02.01.578406 — animal behavior and cognition — Posted on 2024-02-04
4169 Jag1 represses Notch activation in lateral supporting cells and inhibits an outer hair cell fate in the medial compartment of the developing cochlea
de Haan, S.; Corbat, A. A.; Cederroth, C. R.; Autrum, L. G.; Hankeova, S.; Driver, E. C.; Canlon, B.; Kelley, M. W.; Andersson, E. R.
10.1101/2024.02.02.577075 — developmental biology — Posted on 2024-02-04
4170 Energy scarcity and impaired mitochondrial translation induce perinuclear stress granule clustering
Fernadez-Pelayo, U.; Munoz-Oreja, M.; Villar-Fernandez, M.; Lopez de Arbina, A.; Aiestaran- Zelaia, I.; Sanchez-Guisado, M. J.; Pantic, B.; Elicegui, A.; Zufiria, M.; Iruzubieta, P.; Sagartzazu-Aizpurua, M.; Aizpurua, J. M.; Gegg, M.; Alonso-Martin, S.; Ruiz-Cabello, J.; Gil Bea, F.; Spinazzola, A.; Lopez de Munain, A.; Holt, I.
10.1101/2024.02.01.578399 — cell biology — Posted on 2024-02-04
4171 Npbwr1 signaling mediates fast antidepressant action
Stein, G.; Aly, J. S.; Lange, L.; Manzolillo, A.; Riege, K.; Brancato, A.; Huebner, C. A.; Turecki, G.; Hoffmann, S.; Engmann, O.
10.1101/2024.02.02.578166 — neuroscience — Posted on 2024-02-04
4173 Pia-FLOW: Deciphering hemodynamic maps of the pial vascular connectome and its response to arterial occlusion
Glueck, C.; Zhou, Q.; Droux, J.; Chen, Z.; Glandorf, L.; Wegener, S.; Razansky, D.; Weber, B.; EL AMKI, M.
10.1101/2024.02.02.577749 — neuroscience — Posted on 2024-02-04
4174 Representational dissimilarity component analysis (ReDisCA)
Ossadtchi, A.; Semenkov, I.; Zhuravleva, A.; Serikov, O.; Voloshina, E.
10.1101/2024.02.01.578343 — neuroscience — Posted on 2024-02-04
4176 NeuroTri2-VISDOT: An open-access tool to harness the power of second trimester human single cell data to inform models of Mendelian neurodevelopmental disorders
Clark, K. J.; Lubin, E. E.; Gonzalez, E. M.; Sangree, A. K.; Layo-Carris, D. E.; Durham, E. L.; Ahrens-Nicklas, R. C.; Nomakuchi, T. T.; Bhoj, E. J. K.
10.1101/2024.02.01.578438 — genetics — Posted on 2024-02-04
4177 Single-molecule chromatin configurations link transcription factor binding to expression in human cells
Doughty, B. R.; Hinks, M. M.; Schaepe, J. M.; Marinov, G. K.; Thurm, A. R.; Rios-Martinez, C.; Parks, B. E.; Tan, Y.; Marklund, E.; Dubocanin, D.; Bintu, L.; Greenleaf, W. J.
10.1101/2024.02.02.578660 — molecular biology — Posted on 2024-02-04
4179 Counter-regulation of RNA stability by UPF1 and TDP43
Gomez, N.; Hsieh, C.; Li, X.; Dykstra, M.; Waksmacki, J.; Altheim, C.; Bechar, Y.; Klim, J.; Zaepful, B.; Rothstein, J.; Tank, E. M.; Barmada, S. J.
10.1101/2024.01.31.578310 — neuroscience — Posted on 2024-02-04
4180 Sex Differences in the Brain's White Matter Microstructure during Development assessed using Advanced Diffusion MRI Models
Benavidez, S. M.; Abaryan, Z.; Kim, G. S.; Laltoo, E.; McCracken, J. T.; Thompson, P. M.; Lawrence, K. E.
10.1101/2024.02.02.578712 — neuroscience — Posted on 2024-02-04
4183 A rapid approach for sex assignment by RAD-seq using a reference genome
Peralta, D. M.; Tunez, J. I.; Rodriguez Cruz, U. E.; Ceballos, S. G.
10.1101/2023.01.30.526394 — bioinformatics — Posted on 2024-02-04
4186 THE WIP6 TRANSCRIPTION FACTOR TOO MANY LATERALS SPECIFIES VEIN TYPE IN C4 AND C3 GRASS LEAVES
Vlad, D.; Zaidem, M.; Perico, C.; Sedelnikova, O.; Bhattacharya, S.; Langdale, J. A.
10.1101/2023.12.20.572592 — plant biology — Posted on 2024-02-04
4187 Enhancing mitochondrial pyruvate metabolism ameliorates myocardial ischemic reperfusion injury.
Visker, J. R.; Cluntun, A. A.; Velasco-Silva, J. N.; Eberhardt, D. R.; Shankar, T. S.; Hamouche, R.; Ling, J.; Kwak, H.; Hillas, Y.; Aist, I.; Tseliou, E.; Navankasattusas, S.; Chaudhuri, D.; Ducker, G. S.; Drakos, S. G.; Rutter, J.
10.1101/2024.02.01.577463 — physiology — Posted on 2024-02-04
4190 Primary auditory cortex is necessary for the acquisition and expression of categorical behavior
Krall, R. F.; Chambers, C. N.; Arnold, M. P.; Brougher, L. I.; Chen, J.; Deshmukh, R.; King, H. B.; Morford, H. J.; Wiemann, J. M.; Williamson, R. S.
10.1101/2024.02.02.578700 — neuroscience — Posted on 2024-02-04
4191 Semi-synthetic glycoconjugate vaccine candidate against Cryptococcus neoformans
Crawford, C. J.; Liporagi-Lopes, L.; Coelho, C.; Santos Junior, S. R.; Nicola, A. M.; Wear, M. P.; Oscarson, S.; Casadevall, A.
10.1101/2024.02.02.578725 — immunology — Posted on 2024-02-03
4194 Tryptanthrin Analogs Substoichiometrically Inhibit Seeded and Unseeded Tau4RD Aggregation
James, E. I.; Baggett, D. W.; Chang, E.; Schachter, J.; Nixey, T.; Choi, K.; Guttman, M.; Nath, A.
10.1101/2024.02.02.578649 — biochemistry — Posted on 2024-02-03
4195 Triplex real-time PCR ZKIR-T assay for simultaneous detection of the Klebsiella pneumoniae species complex and identification of K. pneumoniae sensu stricto
Ligowska-Marzeta, M.; Barbier, E.; Rodrigues, C.; Piveteau, P.; Schroeder Hansen, D.; Hartmann, A.; Moller-Nielsen, E.; Brisse, S.
10.1101/2024.02.02.578617 — microbiology — Posted on 2024-02-03
4196 Characterization and functional analysis of Toxoplasma Golgi-associated proteins identified by proximity labelling
Pasquarelli, R. R.; Quan, J. J.; Yang, V.; Britton, T. A.; Sha, J.; Wohlschlegel, J. A.; Bradley, P. J.
10.1101/2024.02.02.578703 — microbiology — Posted on 2024-02-03
4197 Comprehensive analysis of the microbial consortium in the culture of flagellate Monocercomonoides exilis
Jimenez-Gonzalez, A.; Treitli, S. C.; Pena-Diaz, P.; Janovska, A.; Benes, V.; Zacek, P.; Hampl, V.
10.1101/2024.02.02.578639 — microbiology — Posted on 2024-02-03
4200 PackDock: a Diffusion Based Side Chain Packing Model for Flexible Protein-Ligand Docking
Zhang, R.; Jiang, X.; Cao, D.; Yu, J.; Chen, M.; Fan, Z.; Kong, X.; Xiong, J.; Zhang, Z.; Zhang, W.; Ni, S.; Wang, Y.; Gao, S.; Zheng, M.
10.1101/2024.01.31.578200 — bioinformatics — Posted on 2024-02-03
4204 Transcriptional responses to priority effects in nectar yeast
Chappell, C. R.; Goddard, P.; Golden, L.; Hernandez, J.; Ortiz Chavez, D.; Hossine, M.; Herrera Paredes, S.; Fukami, T.; Dhami, M. K.
10.1101/2024.01.30.578081 — ecology — Posted on 2024-02-03
4207 Lipidomics of homeoviscous adaptation to low temperatures in Staphylococcus aureus utilizing exogenous straight-chain unsaturated fatty acids over biosynthesized endogenous branched-chain fatty acids
Barbarek, S. C.; Shah, R.; Paul, S.; Alvarado, G.; Appala, K.; Henderson, E. C.; Strandquist, E. T.; Pokorny, A.; Singh, V. K.; Gatto, C.; Dahl, J.-U.; Hines, K. M.; Wilkinson, B. J.
10.1101/2024.02.02.578686 — microbiology — Posted on 2024-02-03
4208 P. aeruginosa tRNA-fMet halves secreted in outer membrane vesicles suppress lung inflammation in Cystic Fibrosis
Li, Z.; Barnaby, R.; Nymon, A.; Roche, C.; Koeppen, K.; Ashare, A.; Hogan, D.; Gerber, S. A.; Taatjes, D.; Hampton, T. H.; Stanton, B.
10.1101/2024.02.03.578737 — microbiology — Posted on 2024-02-03
4210 Niche exclusion of a lung pathogen in mice with designed probiotic communities
Hern, K. E.; Phillips, A. M. E.; Mageeney, C. M.; Williams, K. P.; Sinha, A.; Carlson, H. K.; Collette, N. M.; Branda, S. S.; Arkin, A. P.
10.1101/2024.02.02.578711 — microbiology — Posted on 2024-02-03
4211 PPARγ mediated enhanced lipid biogenesis fuels Mycobacterium tuberculosis growth in hepatocytes.
Sarkar, B.; Singh, J.; Yadav, M.; Sharma, P.; Sharma, R. D.; Singh, S.; Chandramouli, A.; Kumar, A.; Kamat, S. S.; Ghorpade, D. S.; Mohanty, D.; Kumar, D.; Gokhale, R. S.
10.1101/2024.02.02.578554 — microbiology — Posted on 2024-02-03
4213 Iron deficiency causes aspartate-sensitive metabolic and proliferative dysfunction in CD8+ T cells
Teh, M. R.; Gudgeon, N.; Frost, J. N.; Sinclair, L. V.; Smith, A. L.; Millington, C. L.; Kronsteiner, B.; Roberts, J.; Marzullo, B. P.; Preston, A. E.; Rehwinkel, J.; Milne, T. A.; Tennant, D. A.; Dunachie, S. J.; Armitage, A. E.; Dimeloe, S. K.; Drakesmith, H.
10.1101/2024.02.01.578381 — immunology — Posted on 2024-02-03
4215 Different fluorescent labels report distinct components of spHCN channel voltage sensor movement
Wojciechowski, M. N.; McKenzie, C.; Hung, A.; Kuanyshbek, A.; Soh, M. S.; Reid, C. A.; Forster, I. C.
10.1101/2024.01.23.576936 — biophysics — Posted on 2024-02-03
4217 Novel spirocyclic dimer, SpiD3, targets chronic lymphocytic leukemia survival pathways with potent preclinical effects
Eiken, A.; Smith, A. L.; Skupa, S. A.; Schmitz, E.; Rana, S.; Singh, S.; Kumar, S.; Mallareddy, J. R.; de Cubas, A. A.; Krishna, A.; Kalluchi, A.; Rowley, J.; D'Angelo, C. R.; Lunning, M. A.; Bociek, R. G.; Vose, J. M.; Natarajan, A.; ElGamal, D.
10.1101/2024.01.31.578283 — cancer biology — Posted on 2024-02-03
4218 Grayscale 4D Biomaterial Customization at High Resolution and Scale
Batalov, I.; Filteau, J. R.; Francis, R. M.; Jaindl, G.; Orr, L.; Rapp, T. L.; Yang, S.; Filteau, J. A.; Xie, W.; Bretherton, R. C.; Glaser, A. K.; Liu, J. T. C.; Stevens, K. R.; DeForest, C. A.
10.1101/2024.01.31.578280 — bioengineering — Posted on 2024-02-03
4220 Clostridioides difficile-mucus interactions encompass shifts in gene expression, metabolism, and biofilm formation
Furtado, K. L.; Plott, L. M.; Markovetz, M. R.; Powers, D. A.; Wang, H.; Hill, D. B.; Papin, J. A.; Allbritton, N. L.; Tamayo, R.
10.1101/2024.02.01.578425 — microbiology — Posted on 2024-02-03
4221 Retrograde adenosine/A2A receptor signaling facilitates excitatory synaptic transmission and seizures
Nasrallah, K.; Berthoux, C.; Hashimotodani, Y.; Chavez, A. E.; Gulfo, M.; Lujan, R.; Castillo, P. E.
10.1101/2021.10.07.463512 — neuroscience — Posted on 2024-02-03
4222 Targeting neuroinflammation by pharmacologic down-regulation of inflammatory pathways is neuroprotective in protein misfolding disorders.
Risen, S. J.; Boland, S.; Sharma, S.; Weismann, G.; Shirley, P.; Latham, A. S.; Hay, A. J. D.; Gilberto, V. S.; Hines, A. D.; Brindley, S.; Brown, J. M.; McGrath, S.; Chatterjee, A.; Nagpal, P.; Moreno, J. A.
10.1101/2022.09.26.509513 — neuroscience — Posted on 2024-02-03
4223 A Data-Driven Latent Variable Approach to Validating the Research Domain Criteria (RDoC) Framework
Quah, S. K. L.; Jo, B.; Geniesse, C.; Uddin, L. Q.; Mumford, J. A.; Barch, D. M.; Fair, D. A.; Gotlib, I. H.; Poldrack, R. A.; Saggar, M.
10.1101/2024.01.31.577486 — neuroscience — Posted on 2024-02-03
4224 Three-dimensional assessments are necessary to determine the true, spatially-resolved composition of tissues
Forjaz, A.; Vaz, E.; Romero, V. M.; Joshi, S.; Braxton, A. M.; Jiang, A. C.; Fujikura, K.; Cornish, T.; Hong, S.-M.; Hruban, R. H.; Wu, P.-H.; Wood, L. D.; Kiemen, A. L.; Wirtz, D.
10.1101/2023.12.04.569986 — cancer biology — Posted on 2024-02-03
4225 A Genetic Screen for regulators of CNS morphology in Drosophila
Lacin, H.; Zhu, Y.; DiPaola, J.; Wilson, B. A.; Zhu, Y.; Skeath, J. B.
10.1101/2024.01.09.574922 — genetics — Posted on 2024-02-03
4228 Wheat NAC transcription factor NAC5-1 is a positive regulator of senescence
Evans, C.; Mogg, S. L.; Soraru, C.; Wallington, E.; Coates, J. C.; Borrill, P.
10.1101/2024.02.02.578592 — plant biology — Posted on 2024-02-03
4229 Identification and characterization of a temperature sensitive chlorotic soybean mutant
Hancock, C. N.; Germany, T.; Redd, P.; Timmons, J.; Lipford, J.; Burns, S.; Cervantes-Perez, S. A.; Libault, M.; Shen, W.; An, Y.-q. C.; Kanizay, L.; Yerka, M.; Parrott, W. A.
10.1101/2024.02.02.578604 — plant biology — Posted on 2024-02-03
4231 Grapevine cell response to carbon deficiency requires transcriptome and methylome reprogramming
Berger, M. M. J.; Garcia, V.; Lacrampe, N.; Rubio, B.; Decros, G.; Petriacq, P.; Flandin, A.; Cassan, C.; Hilbert-Masson, G.; Colombie, S.; Atanassova, R.; Gallusci, P.
10.1101/2024.02.02.578586 — plant biology — Posted on 2024-02-03
4233 Reducing stomatal density by expression of a synthetic EPF increases leaf intrinsic water use efficiency and reduces plant water use in a C4 crop
Ferguson, J. N.; Schmuker, P.; Dmitrieva, A.; Quach, T.; Zhang, T.; Ge, Z.; Nersesian, N.; Sato, S.; Clemente, T.; Leakey, A.
10.1101/2024.02.01.578512 — plant biology — Posted on 2024-02-03
4234 FoxO factors are essential for maintaining organ homeostasis by acting as stress sensors in airway epithelial cells
Uliczka, K.; Bossen, J. M.; Zissler, U.; Fink, C.; Niu, X.; Pieper, M.; Prange, R. D.; Vock, C.; Wagner, C.; Knop, M.; Abdelsadik, A.; Franzenburg, S.; Bruchhaus, I.; Wegmann, M.; Schmidt-Weber, C. B.; König, P.; Pfefferle, P.; Heine, H.; Roeder, T.
10.1101/2024.01.31.578231 — physiology — Posted on 2024-02-03
4235 Impaired motor-to-sensory transformation mediates auditory hallucinations
Yang, F.; Zhu, H.; Cao, X.; Li, H.; Fang, X.; Yu, L.; Li, S.; Wu, Z.; Li, C.; Zhang, C.; Tian, X.
10.1101/2023.06.10.544451 — neuroscience — Posted on 2024-02-03
4238 Development of a cell-based DIFF-rGFP assay system for generalized discovery of viral protease Inhibitors
Xiaoyan, W.; Yan, F.; Ruiting, C.; Chenjie, F.; Shuai, W.; Huimin, S.; Shuling, J.; Jiasheng, S.; Beibei, W.
10.1101/2024.02.01.577684 — molecular biology — Posted on 2024-02-03
4240 Dissecting quantitative trait nucleotides by saturation genome editing
Roy, K. R.; Smith, J. D.; Li, S.; Vonesch, S. C.; Nguyen, M.; Burnett, W. T.; Orsley, K. M.; Lee, C.-S.; Haber, J. E.; St.Onge, R. P.; Steinmetz, L. M.
10.1101/2024.02.02.577784 — genetics — Posted on 2024-02-02
4242 Hexagons all the way down: Grid cells as a conformal isometric map of space
Schoyen, V. S.; Beshkov, K.; Pettersen, M. B.; Hermansen, E.; Holzhausen, K.; Malthe-Sorenssen, A.; Fyhn, M.; Lepperod, M. E.
10.1101/2024.02.02.578585 — neuroscience — Posted on 2024-02-02
4244 Independent regulation of early trafficking of NMDA receptors by ligand-binding domains of the GluN1 and GluN2A subunits
Netolicky, J.; Zahumenska, P.; Misiachna, A.; Kolcheva, M.; Kucera, T.; Fibigar, J.; Rehakova, K.; Hemelikova, K.; Kortus, S.; Langore, E.; Ladislav, M.; Korabecny, J.; Horak, M.
10.1101/2024.02.02.578575 — neuroscience — Posted on 2024-02-02
4245 Serotonin drives aggression and social behaviours of laboratory mice in a semi-natural environment
Rivalan, M.; Alonso, L.; Mosienko, V.; Bey, P.; Hyde, A.; Bader, M.; Winter, Y.; Alenina, N.
10.1101/2024.02.02.578690 — neuroscience — Posted on 2024-02-02
4248 Microtubules ensure transport of vegetative nuclei and sperm cells by fine-tuning their home positions
Motomura, K.; Tsuchi, H.; Komojiri, M.; Matsumoto, A.; Sugi, N.; Susaki, D.; Takeda, A.; Kinoshita, T.; Maruyama, D.
10.1101/2024.01.31.578224 — plant biology — Posted on 2024-02-02
4249 The T-cell niche tunes immune function through modulation of the cytoskeleton and TCR-antigen forces
Kellner, A. V.; Hunter, R.; Do, P.; Eggert, J.; Jaffe, M.; Geitgey, D. K.; Lee, M.; Hamilton, J. A. G.; Ross, A. J.; Ank, R. S.; Bender, R. L.; Ma, R.; Porter, C. C.; Dreaden, E. C.; Au-Yeung, B. B.; Haynes, K. A.; Henry, C. J.; Salaita, K.
10.1101/2024.01.31.578101 — bioengineering — Posted on 2024-02-02
4250 A weaponized phage suppresses competitors in historical and modern metapopulations of pathogenic bacteria
Backman, N.; Latorre, S. M.; Symeonidi, E.; Muszynski, A.; Bleak, E.; Eads, L.; Martinez-Koury, P.; Som, S.; hawks, A.; Gloss, A. D.; Belnap, D.; Manuel, A. M.; Deutschbauer, A.; Bergelson, J.; Azadi, P.; Burbano-Roa, H. A.; Karasov, T.
10.1101/2023.04.17.536465 — microbiology — Posted on 2024-02-02
4251 Phylogenetically and structurally diverse reductive dehalogenases link biogeochemical cycles in deep-sea cold seeps
Han, Y.; Peng, Y.; Peng, J.; Cao, L.; Xu, Y.; Yang, Y.; Wu, M.; Zhou, H.; Zhang, C.; Zhang, D.; Wang, M.; Greening, C.; Dong, X.
10.1101/2024.01.23.576788 — microbiology — Posted on 2024-02-02
4252 Neurotrophic factor Neuritin modulates T cell electrical and metabolic state for the balance of tolerance and immunity
Yu, H.; Nishio, H.; Barbi, J.; Mitchell-Flack, M.; Vignali, P. D. A.; Zheng, Y.; Lebid, A.; Chang, K.-Y.; Fu, J.; Higgins, M.; Huang, C.-T.; Zhang, X.; Li, Z.; Blosser, L.; Tam, A.; Drake, C. G.; Pardoll, D. M.
10.1101/2024.01.31.578284 — immunology — Posted on 2024-02-02
4255 A multiple Arc (mArc) tagging system to uncover the organizational principles of multiple memories
Stackmann, M.; Yelhekar, T. D.; Meng, M.; Sun, X.; Nthumba, J.; Bulthuis, N. E.; Vaughan, N.; Zhu, E.; Lin, Y.; Denny, C. A.
10.1101/2024.02.01.578410 — neuroscience — Posted on 2024-02-02
4258 MAIT Cells Modulate Innate Immune Cells and Inhibit Colon Cancer Growth
Cheng, O. J.; Lebish, E. J.; Jensen, O.; Jacenik, D.; Trivedi, S.; Cacioppo, J.; Aube, J.; Beswick, E. J.; Leung, D. T.
10.1101/2024.01.16.575894 — cancer biology — Posted on 2024-02-02
4269 Individualized functional connectivity markers associated with motor and mood symptoms of Parkinson's disease
Dahmani, L.; Bai, Y.; Zhang, W.; Ren, J.; Li, S.; Hu, Q.; Fu, X.; Ma, J.; Wei, W.; Wang, M.; Liu, H.; Wang, D.
10.1101/2024.01.31.578238 — neuroscience — Posted on 2024-02-02
4270 Aging is associated with a modality-specific decline in taste
Brown, E. B.; Lloyd, E.; Martin-Pena, A.; McFarlane, S.; Dahanukar, A.; Keene, A. C.
10.1101/2024.02.01.578408 — neuroscience — Posted on 2024-02-02
4271 AAV-based delivery of RNAi targeting Ataxin-2 improves survival, strength, and pathology in mouse models of rapidly and slowly progressive sporadic ALS
Amado, D. A.; Robbins, A. B.; Smith, A. R.; Whiteman, K. R.; Chillon Bosch, G.; Chen, Y.; Fuller, J. A.; Izda, A.; Nelson, S.; Dichter, A. I.; Monteys, A. M.; Davidson, B. L.
10.1101/2024.01.31.578314 — neuroscience — Posted on 2024-02-02
4272 Targeting Heterochromatin Eliminates Malignant Stem Cells in Chronic Myelomonocytic Leukemia Through Reactivation of Retroelements and Innate Immune pathways
Hidaoui, D.; Chelbi, R.; Bohm, M.; Porquet, A.; Polizou, A.; Alcazer, V.; Depil, S.; Imanci, A.; Morabito, M.; Renneville, A.; Selimoglu-Buet, D.; Thepot, S.; Itzykson, R.; Laplane, L.; Droin, N.; Trompouki, E.; Elvira-Matelot, E.; Solary, E.; PORTEU, F.
10.1101/2024.02.02.578583 — cancer biology — Posted on 2024-02-02
4274 Temperature-induced changes in protein interactions control RNA recruitment to G3BP1 condensates
Fischer, C. M.; Ausserwoger, H.; Sneideris, T.; Qian, D.; Scrutton, R.; Qamar, S.; St George-Hyslop, P.; Knowles, T. P. J.
10.1101/2024.02.02.578543 — biophysics — Posted on 2024-02-02
4277 Improved nuclease-based prime editing by DNA repair modulation and pegRNA engineering
Antoniou, P.; Dacquay, L.; Selfjord, N.; Madeyski-Bengtson, K.; Loyd, A.-L.; Gordon, E.; Thom, G.; Hsieh, P.-P.; Wimberger, S.; Svikovic, S.; Firth, M.; Akrap, N.; Maresca, M.; Peterka, M.
10.1101/2024.02.01.578377 — bioengineering — Posted on 2024-02-02
4280 Conformational plasticity of a BiP-GRP94 chaperone complex
Brenner, J. C.; Zirden, L. C.; Almeida-Hernandez, Y.; Kaschani, F.; Kaiser, M.; Sanchez-Garcia, E.; Poepsel, S.; Hellerschmied, D.
10.1101/2024.02.01.578445 — biochemistry — Posted on 2024-02-02
4281 Molecular basis of ligand promiscuity, structural mimicry, and atypical dimerization in the chemokine receptors
Saha, S.; Sano, F. K.; Sharma, S.; Ganguly, M.; Saha, S.; Akasaka, H.; Kobayashi, T. A.; Zaidi, N.; Mishra, S.; Dalal, A.; Mohapatra, S.; Yadav, M.; Itoh, Y.; Leurs, R.; Chevigne, A.; Banerjee, R.; Shihoya, W.; Nureki, O.; SHUKLA, A. K.
10.1101/2024.02.01.578380 — biochemistry — Posted on 2024-02-02
4284 DNA metabarcoding diet analysis in ruminants is quantitative and integrates feeding over several weeks
Kamenova, S.; Meyer, P.; Brysting, A. K.; Rescia, L.; Folkow, L. P.; Sundset, M. A.; Coissac, E.; Gusarova, G.
10.1101/2024.02.01.577814 — ecology — Posted on 2024-02-02
4286 Depth-dependent dynamics of protist communities as an integral part of spring succession in a freshwater reservoir
Mukherjee, I.; Grujcic, V.; Salcher, M. M.; Znachor, P.; Seda, J.; Devetter, M.; Rychtecky, P.; Simek, K.; Shabarova, T.
10.1101/2024.02.01.578394 — ecology — Posted on 2024-02-02
4288 The DNA-repair protein APE1 participates with hnRNPA2B1 to motif-enriched and prognostic miRNA secretion
Mangiapane, G.; Notarangelo, M.; Canarutto, G.; Fabbiano, F.; Dalla, E.; Degrassi, M.; Antoniali, G.; Gualandi, N.; De Sanctis, V.; Piazza, S.; D'Agostino, V. G.; Tell, G.
10.1101/2024.02.02.578563 — molecular biology — Posted on 2024-02-02
4293 A metagenomics-based survey of the virus diversity in mosquito vectors allows the first detection of Sindbis virus in Burkina Faso
Kabore, D.; Exbrayat, A.; charriat, f.; Soma, D. D.; Sawadogo, S.; Ouedraogo, G. A.; Tuaillon, E.; Van de Perre, P.; Baldet, T.; Dabire, R. K.; Gil, P.; Gutierrez, S.
10.1101/2024.02.02.578537 — microbiology — Posted on 2024-02-02
4298 Quantification of beta cell carrying capacity in prediabetes
Woller, A.; Tamir, Y.; Bar, A.; Mayo, A.; Rein, M.; Godneva, A.; Mendelson Cohen, N.; Segal, E.; Toledano, Y.; Shilo, S.; Gonze, D.; Alon, U.
10.1101/2024.01.31.578144 — systems biology — Posted on 2024-02-02
4301 Selective degradation of multimeric proteins via chemically induced proximity to TRIM21
Lu, P.; Cheng, Y.; Xue, L.; Ren, X.; Chen, C.; Li, J.; Wu, Q.; Sun, S.; Hou, J.; Jia, W.; Li, C.; Qi, X.; Huang, N.; Han, T.
10.1101/2024.01.31.578122 — pharmacology and toxicology — Posted on 2024-02-02
4302 Disconnection Between Microvascular Damage and Neurodegeneration in Early Diabetic Retinopathy
Yang, Q.; Yasvoina, M.; Olvera-Barrios, A.; Mendes, J.; Zhu, M.; Egan, C.; Tufail, A.; Fruttiger, M.
10.1101/2024.01.31.577770 — pathology — Posted on 2024-02-02
4303 MYBL2 drives prostate cancer plasticity and identifies CDK2 as a therapeutic vulnerability in RB1-loss and neuroendocrine prostate cancer
Ellis, L.; German, B.; Singh, J. N.; Burkhart, D. L.; Sheahan, A.; Bergom, H.; Morel, K. L.; Beltran, H.; Hwang, J.; Lawrenson, K.
10.1101/2024.01.31.578216 — cancer biology — Posted on 2024-02-02
4305 Translational T-box riboswitches bind tRNA by modulating conformational flexibility
Campos-Chavez, E.; Paul, S.; Zhou, Z.; Alonso, D.; Verma, A. R.; Fei, J.; Mondragon, A.
10.1101/2024.02.02.578613 — biophysics — Posted on 2024-02-02
4308 Physicochemical Principles Driving Small Molecule Binding to RNA
Allen, T. E. H.; McDonagh, J. L.; Broncel, M.; Bryant, C. J.; Incarnato, D.; Vasudevan, A.; Khan, R. T.
10.1101/2024.01.31.578268 — bioinformatics — Posted on 2024-02-02
4310 Metabolic priming of GD2 TRAC-CAR T cellsduring manufacturing promotes memory phenotypes while enhancing persistence
Cappabianca, D.; Pham, D.; Forsberg, M. H.; Bugel, M.; Tommasi, A.; Lauer, A.; Vidugiriene, J.; Hrdlicka, B.; McHale, A.; Sodji, Q.; Skala, M. C.; Capitini, C. M.; Saha, K.
10.1101/2024.01.31.575774 — bioengineering — Posted on 2024-02-02
4313 miR-210 is essential to retinal homeostasis in fruit flies and mice
Colaianni, D.; Virga, F.; Tisi, A.; Stefanelli, C.; Zaccagnini, G.; Cusumano, P.; Sales, G.; Ivan, M.; Martelli, F.; Taverna, D.; Mazzone, M.; Bertolucci, C.; Maccarone, R.; De Pitta, C.
10.1101/2024.01.30.577988 — genetics — Posted on 2024-02-02
4317 FGF2 promotes the expansion of parietal mesothelial progenitor pools and inhibits BMP4-mediated smooth muscle cell differentiation
Hwang, Y.; Shimamura, Y.; Tanaka, J.; Miura, A.; Sawada, A.; SARMAH, H.; Shimizu, D.; Kondo, Y.; Ninish, Z.; Yamada, K.; Mori, M.
10.1101/2024.01.31.577512 — developmental biology — Posted on 2024-02-02
4320 Somite-independent regeneration of the axolotl primary body axis
Masselink, W.; Gerber, T.; Falcon, F.; Deshayes, T.; Papadopoulos, S.-C.; Pende, M.; Singh Jamwal, V.; Taniguchi-Sugiura, Y.; Lin, T.-Y.; Kurth, T.; Wang, J.; Arendt, D.; Fei, J.-F.; Treutlein, B.; Tanaka, E. M.; Murawala, P.
10.1101/2024.01.31.577464 — developmental biology — Posted on 2024-02-02
4323 Disruption of DLL4/NOTCH1 Causes Dysregulated PPARγ/AKT Signaling in Pulmonary Arterial Hypertension
Awad, K. S.; Wang, S.; Dougherty, E. J.; Keshavarz, A.; Demirkale, C. Y.; Yu, Z.-X.; Miller, L.; Elinoff, J. M.; Danner, R. L.
10.1101/2024.01.31.578230 — cell biology — Posted on 2024-02-02
4326 Autoinflammatory patients with Golgi-trapped CDC42 exhibit intracellular trafficking defects leading to STING hyperactivation
Iannuzzo, A.; Delafontaine, S.; El Masri, R.; Tacine, R.; Prencipe, G.; Nishitani-Isa, M.; van Wijck, R. T.; Bhuyan, F.; Rasheed, A. A. d. J.; Coppola, S.; van Daele, P. L.; Insalaco, A.; Goldbach-Mansky, R.; Yasumi, T.; Tartaglia, M.; Meyts, I.; Delon, J.
10.1101/2024.01.31.578189 — immunology — Posted on 2024-02-02
4327 The Switchmaze: an open-design device for measuring motivation and drive switching in mice
Hartmann, C.; Mahajan, A.; Borges, V.; Razenberg, L.; Thoennes, Y.; Karnani, M. M.
10.1101/2024.01.31.578188 — neuroscience — Posted on 2024-02-02
4332 Single-Cell Peripheral Immunoprofiling of Lewy Body Disease in a Multi-site Cohort
Phongpreecha, T.; Mathi, K.; Cholerton, B.; Fox, E. J.; Espinosa, C.; Hwang, L.-J. L.; Sigal, N.; Gajera, C.; Berson, E.; Perna, A.; Xie, F.; Shu, C.-H.; Hazra, D.; Reincke, M.; Chung, P.; Channappa, D.; Dunn, J.; Kipp, L. B.; Poston, K. L.; Montine, K. S.; Maecker, H. T.; Aghaeepour, N.; Montine, T. J.
10.1101/2024.01.30.578082 — neuroscience — Posted on 2024-02-02
4333 Activation of XBP1s attenuates disease severity in models of proteotoxic Charcot-Marie-Tooth type 1B
Touvier, T.; Veneri, F. A.; Claessens, A.; Ferri, C.; Mastrangelo, R.; Sorgiati, N.; Bianchi, F.; Valenzano, S.; Del Carro, U.; Rivellini, C.; Duong, P.; Shy, M. E.; Kelly, J. W.; Svaren, J.; Wiseman, R. L.; D'Antonio, M.
10.1101/2024.01.31.577760 — neuroscience — Posted on 2024-02-02
4336 Cardiomyocyte PGC-1α enables physiological adaptations to endurance exercise through suppression of GDF15 and cardiac atrophy
Khetarpal, S. A.; Li, H.; Vitale, T.; Rhee, J.; Grauvogel, L.; Castro, C.; Mittenbühler, M. J.; Houstis, N. E.; Vargas-Castillo, A.; Smythers, A. L.; Liu, J.; Curtin, C.; Sprenger, H.-G.; Blackmore, K. A.; Kuznetsov, A.; Freeman, R.; Bogoslavski, D.; Ellinor, P. T.; Asnani, A.; Dumesic, P. A.; Puigserver, P.; Roh, J. D.; Spiegelman, B. M.; Rosenzweig, A.
10.1101/2024.01.30.578093 — physiology — Posted on 2024-02-02
4337 MXRA8 promotes adipose tissue whitening to drive obesity
Jia, W.; Giwa, R.; Moley, J. R.; Smith, G. I.; Petersen, M. C.; Field, R. L.; Abousaway, O.; Kim, A. S.; Coffey, S. R.; Varnum, S.; Wright, J. M.; Zhang, X.; Krysa, S.; Lodhi, I. J.; Abumrad, N. A.; Klein, S.; Diamond, M. S.; Brestoff, J. R.
10.1101/2024.01.31.578211 — physiology — Posted on 2024-02-02
4338 Perinatal ampicillin administration modulates murine bile acid metabolism in vivo - an observational study
Thomas, S. P.; Askarian, F.; Kousha, A.; Suzuki, E.; Tsai, C. M.; Liu, G.; Nizet, V.; Dorrestein, P. C.; Tsunoda, S.
10.1101/2024.01.31.578215 — pharmacology and toxicology — Posted on 2024-02-02
4340 The Effect of Adrenalectomy on Bleomycin-Induced Pulmonary Fibrosis in Mice
McGovern, J.; Perry, C.; Ghincea, A.; Shao, S.; Herzog, E. L.; Sun, H.
10.1101/2024.01.31.577771 — pathology — Posted on 2024-02-02
4341 Correlating fluorescence microscopy, optical and magnetic tweezers to study single chiral biopolymers, tested on DNA plectoneme formation dynamics
Shepherd, J.; Guilbaud, S.; Zhou, Z.; Howard, J.; Burman, M.; Schaefer, C.; Kerrigan, A.; Steele-King, C.; Noy, A.; Leake, M. C.
10.1101/2024.01.18.576226 — biophysics — Posted on 2024-02-02
4344 Phenomics Assistant: An Interface for LLM-based Biomedical Knowledge Graph Exploration
O'Neil, S. T.; Schaper, K.; Elsarboukh, G.; Reese, J. T.; Moxon, S. A. T.; Harris, N. L.; Munoz-Torres, M. C.; Robinson, P. N.; Haendel, M. A.; Mungall, C. J.
10.1101/2024.01.31.578275 — bioinformatics — Posted on 2024-02-02
4345 Integrated Closed-loop Control of Bio-actuation for Proprioceptive Bio-hybrid Robots
Filippi, M.; Balciunaite, A.; georgopoulou, A.; Paniagua, P.; Drescher, F.; Nie, M.; Takeuchi, S.; Clemens, F.; Katzschmann, R.
10.1101/2024.01.30.577987 — bioengineering — Posted on 2024-02-02
4347 Scalable single-cell pooled CRISPR screens with conventional knockout vector libraries
Islam, M.; Yang, Y.; Simmons, A. J.; Xu, Y.; Fisher, E.; Deng, W.; Grieb, B.; Molina, P.; Caestecker, C. d.; Ramirez-Solano, M. A.; Liu, Q.; Tansey, W.; Macara, I. G.; Rathmell, J.; Coffey, R. J.; Lau, K.
10.1101/2024.02.01.578192 — genomics — Posted on 2024-02-02
4348 A hierarchical Bayesian interaction model to estimate cell-type-specific methylation quantitative trait loci incorporating priors from cell-sorted bisulfite sequencing data
Cheng, Y.; Cai, B.; Li, H.; Zhang, X.; D'Souza, G.; Shrestha, S.; Edmonds, A.; Meyers, J.; Fischl, M.; Kassaye, S.; Anastos, K.; Cohen, M.; Aouizerat, B. E.; Xu, K.; Zhao, H.
10.1101/2024.02.01.578272 — genetics — Posted on 2024-02-02
4352 Transcriptional responses to priority effects in nectar yeast
Chappell, C. R.; Goddard, P.; Golden, L.; Hernandez, J.; Ortiz Chavez, D.; Hossine, M.; Herrera Paredes, S.; Fukami, T. R.; Dhami, M.
10.1101/2024.01.30.578081 — ecology — Posted on 2024-02-02
4354 Synthesis of 5-Benzylamino and 5-Alkylamino-substituted Pyrimidoquinoline Derivatives as CSNK2A Inhibitors with Antiviral Activity
Asressu, K. H.; Smith, J. L.; Dickmander, R. J.; Moorman, N. J.; Wellnitz, J.; Popov, K. I.; Axtman, A. D.; Willson, T. M.
10.1101/2024.01.30.578037 — cell biology — Posted on 2024-02-02
4355 HSP60 chaperone deficiency disrupts the mitochondrial matrix proteome and dysregulates cholesterol synthesis
Comert, C.; Kjaer-Sorensen, K.; Hansen, J.; Carlsen, J.; Just, J.; Meany, B. F.; Oestergaard, E.; Luo, Y.; Oxvig, C.; Schmidt-Laursen, L.; Palmfeldt, J.; Fernandez-Guerra, P.; Bross, P.
10.1101/2024.01.31.578131 — cell biology — Posted on 2024-02-02
4356 Dissecting reprogramming heterogeneity at single-cell resolution using scTF-seq
Liu, W.; Saelens, W.; Rainer, P.; Biocanin, M.; Gardeux, V.; Gralak, A.; van Mierlo, G.; Russeil, J.; Liu, T.; Chen, W.; Deplancke, B.
10.1101/2024.01.30.577921 — cell biology — Posted on 2024-02-02
4358 IRAK4 autophosphorylation controls inflammatory signaling by activating IRAK oligomerization
Srikanth, N.; Deliz-Aguirre, R.; Gola, D. K.; Bilay, M.; Ziska, E.; Taylor, M. J.
10.1101/2023.12.21.572799 — immunology — Posted on 2024-02-02
4359 Recapitulating memory B cell responses in a Lymphoid Organ-Chip to evaluate mRNA vaccine boosting strategies
Jeger-Madiot, R.; Planas, D.; Staropoli, I.; Kervevan, J.; Mary, H.; Collina, C.; Fonseca, B. F.; Debarnot, H.; Robinot, R.; Gellenoncourt, S.; Schwartz, O.; Ewart, L.; Bscheider, M.; Gobaa, S.; Chakrabarti, L. A.
10.1101/2024.02.02.578553 — immunology — Posted on 2024-02-02
4360 The cortical heartbeat-evoked potential is modulated by heart rate in a task and mental effort dependent manner
Aprile, F.; Simoes, M.; Henriques, J.; de Carvalho, P.; Castelo-Branco, M.; Sel, A.; Ribeiro, M. J.
10.1101/2024.01.31.578137 — neuroscience — Posted on 2024-02-02
4361 Multistability and predominant double-positive states in a four node mutually repressive network: a case study of Th1/Th2/Th17/T-reg differentiation
Duddu, A. S.; Andreas, E.; BV, H.; Grover, K.; Singh, V. R.; Hari, K.; Jhunjhunwala, S.; Cummins, B.; Gedeon, T.; Jolly, M. K.
10.1101/2024.01.30.575880 — systems biology — Posted on 2024-02-02
4362 No cardiac phase bias for threat perception under naturalistic conditions in immersive virtual reality
Klotzsche, F.; Motyka, P.; Molak, A.; Sahula, V.; Darmova, B.; Byrnes, C.; Fajnerova, I.; Gaebler, M.
10.1101/2024.01.31.578172 — physiology — Posted on 2024-02-02
4364 Moth resonant mechanics are tuned to wingbeat frequency and energetic demands.
Wold, E.; Aiello, B.; Harris, M.; Sikandar, U. B.; Lynch, J.; Gravish, N.; Sponberg, S.
10.1101/2024.01.30.578003 — physiology — Posted on 2024-02-02
4366 Development of a LRRC15-Targeted Radio-Immunotheranostic Approach to Deplete Pro-tumorigenic Mechanisms and Immunotherapy Resistance
Storey, C. M.; Altai, M.; Lueckerath, K. M.; Zedan, W.; Zhu, H.; Trajkovic-Arsic, M.; Park, J. E.; Peekhaus, N.; Siveke, J.; Lilljebjorn, H.; Abou, D.; Marks, H. L.; Ulmert, E.; Lilja, H.; Ridley, A.; Safi, M.; Yuen, C.; Geres, S.; Mao, L.; Cheng, M.; Czernin, J.; Herrmann, K.; Bentolila, L.; Yang, X.; Fioretos, T.; Graeber, T.; Sjostrom, K.; Damoiseaux, R.; Thorek, D. L.; Ulmert, D.
10.1101/2024.01.30.577289 — pharmacology and toxicology — Posted on 2024-02-02
4367 Loss of TIM4-Dependent Efferocytosis in Kupffer CellsPromotes Liver Fibrosis in Nonalcoholic Steatohepatitis
Shi, H.; Wang, X.; Gerlach, B.; Yurdagul, A.; Moore, M.; Mirshahi, F.; Ronzoni, L.; Sanyal, A.; Valenti, L.; Lin, C.-S.; Tabas, I.
10.1101/2024.01.30.578023 — pathology — Posted on 2024-02-02
4368 Mechanical confinement governs phenotypic plasticity in melanoma
Hunter, M. V.; Montal, E.; Ma, Y.; Moncada, R.; Yanai, I.; Koche, R. P.; White, R. M.
10.1101/2024.01.30.577120 — cancer biology — Posted on 2024-02-02
4369 A mutant ASXL1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia
Dong, Z.; Sepulveda, H.; Vazquez, L. J. A.; Blouin, C.; Fernandez, J.; Binder, M.; Chou, W.-C.; Tien, H.-F.; Faulkner, G. J.; Myers, S. A.; Patnaik, M.; Rao, A.
10.1101/2024.01.30.578015 — cancer biology — Posted on 2024-02-02
4370 Comprehensive characterization of the viscoelastic properties of Bovine Submaxillary Mucin (BSM) hydrogels and the effect of additives
Rulff, H.; Schmidt, R. F.; Wei, L.-F.; Fentker, K.; Kerkhoff, Y.; Mertins, P.; Mall, M. A.; Lauster, D.; Gradzielski, M.
10.1101/2024.01.17.576019 — biophysics — Posted on 2024-02-02
4375 Detection of prions from spiked and free-ranging carnivore feces
Inzalaco, H. N.; Brandell, E. E.; Wilson, S. P.; Hunsaker, M.; Stahler, D. R.; Woelfel, K.; Walsh, D. P.; Nordeen, T.; Storm, D. J.; Lichtenberg, S. S.; Turner, W. C.
10.1101/2023.07.31.551307 — ecology — Posted on 2024-02-02
4376 Geometric and demographic effects explain contrasting fragmentation-biodiversity relationships across scales
Gelber, S.; Blowes, S. A.; Chase, J. M.; Huth, A.; Schurr, F. M.; Tietjen, B.; Zeller, J. W.; May, F.
10.1101/2024.02.01.577731 — ecology — Posted on 2024-02-02
4378 Reactive oxygen species suppress phagocyte surveillance by oxidizing cytoskeletal regulators
Ferling, I.; Pfalzgraf, S.; Moutounet, L.; Qiu, L.; Li, I.; Zhou, Y.; Freeman, S. A.; Grinstein, S.
10.1101/2024.01.31.578237 — cell biology — Posted on 2024-02-02
4379 Context-dependent functions of mitochondria protein quality control in lung
Xu, L.; Tan, C.; Barr, J.; Talaba, N.; Verheyden, J.; Chin, J. S.; Gaboyan, S.; Advani, I.; Elgamal, R. M.; Gaulton, K. J.; Lin, G.; Afshar, K.; Golts, E.; Meier, A.; Alexander, L. C.; Borok, Z.; Shen, Y.; Chung, W. K.; McCulley, D. J.; Sun, X.
10.1101/2022.12.08.519642 — cell biology — Posted on 2024-02-02
4380 m6a methylation orchestrates IMP1 regulation of microtubules during human neuronal differentiation
Klein, P.; Harley, J.; Crook, H.; Serna, S. E.; Petric-Howe, M.; Roumeliotis, T. I.; Choudhary, J. S.; Chakrabarti, A. M.; Luisier, R.; Patani, R.; Ramos, A.
10.1101/2023.09.12.557394 — molecular biology — Posted on 2024-02-02
4381 Microbial remineralization processes during post-spring-bloom excess phosphate in the northern Baltic Sea
Vanharanta, M.; Santoro, M.; Villena-Alemany, C.; Piiparinen, J.; Piwosz, K.; Grossart, H.-P.; Labrenz, M.; Spilling, K.
10.1101/2024.02.02.577174 — microbiology — Posted on 2024-02-02
4382 Presence of phage-plasmids in multiple serovars of Salmonella enterica
Nair, S.; Barker, C. R.; Bird, M.; Greig, D. R.; Collins, C.; Painset, A.; Chattaway, M.; Pickard, D.; Larkin, L.; Gharbia, S.; Didelot, X.; Ribeca, P.
10.1101/2024.02.02.574330 — microbiology — Posted on 2024-02-02
4383 Pigs are highly susceptible to but do not transmit mink-derived highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b
Kwon, T.; Trujillo, J. D.; Carossino, M.; Lyoo, E. L.; McDowell, C. D.; Cool, K.; Matias-Ferreyra, F. S.; Jeevan, T.; Morozov, I.; Gaudreault, N. N.; Balasuriya, U.; Webby, R. J.; Osterrieder, N.; Richt, J. A.
10.1101/2023.12.13.571575 — microbiology — Posted on 2024-02-02
4386 Biochemical, biomarker, and behavioral characterization of the GrnR493X mouse model of frontotemporal dementia
Smith, D. M.; Aggarwal, G.; Niehoff, M. L.; Jones, S. A.; Banerjee, S.; Farr, S. A.; Nguyen, A. D.
10.1101/2023.05.27.542495 — neuroscience — Posted on 2024-02-02
4389 DePARylation is critical for S phase progression and cell survival
Nie, L.; Wang, C.; Huang, M.; Liu, X.; Feng, X.; Tang, M.; Li, S.; Hang, Q.; Teng, H.; Shen, X.; Ma, L.; Gan, B.; Chen, J.
10.1101/2023.07.31.551317 — cancer biology — Posted on 2024-02-02
4390 Tumor sialylation controls effective anti-cancer immunity in breast cancer
Mereiter, S.; Jonsson, G.; Oliveira, T.; Helm, J.; Hoffmann, D.; Abeln, M.; Jochum, A.-K.; Jochum, W.; Kellner, M. J.; Feith, M.; Tkalec, V.; Wasilewska, K.; Jiao, J.; Emsenhuber, L.; Holstein, F.; Obenauf, A.; Lordello, L.; Scoazec, J.-Y.; Kroemer, G.; Zitvogel, L.; Ali, O. H.; Flatz, L.; Gerardy-Schahn, R.; Muenster-Kuehnel, A.; Stadlmann, J.; Penninger, J. M.
10.1101/2023.09.20.558571 — cancer biology — Posted on 2024-02-02
4392 nanoBERT: A deep learning model for gene agnostic navigation of the nanobody mutational space
Hadsund, J.; Satlawa, T.; Janusz, B.; Shan, L.; Zhou, L.; Rottger, R.; Krawczyk, K.
10.1101/2024.01.31.578143 — bioinformatics — Posted on 2024-02-02
4393 An endothelial SOX18-mevalonate pathway axis enables repurposing of statins for infantile hemangioma
Holm, A.; Graus, M.; Wylie-Sears, J.; Borgelt, L.; Tan, J. W. H.; Nasim, S.; Chung, L.; Jain, A.; Sun, M.; Sun, L.; Brouillard, P.; Lekwuttikarn, R.; Kozakewich, H.; Qi, Y. J.; Teng, J.; Mulliken, J.; Vikkula, M.; Francois, M.; Bischoff, J.
10.1101/2024.01.29.577829 — molecular biology — Posted on 2024-02-02
4394 Thalamic feedback shapes brain responses evoked by cortical stimulation in mice and humans
Russo, S.; Claar, L.; Marks, L.; Krishnan, G.; Furregoni, G.; Zauli, F. M.; Hassan, G.; Solbiati, M.; d'Orio, P.; Mikulan, E.; Sarasso, S.; Rosanova, M.; Sartori, I.; Bazhenov, M.; Pigorini, A.; Massimini, M.; Koch, C.; Rembado, I.
10.1101/2024.01.31.578243 — neuroscience — Posted on 2024-02-02
4395 Mice born preterm develop gait dystonia and reduced cortical parvalbumin immunoreactivity
Gemperli, K.; Folorunso, F.; Norin, B.; Joshua, R.; Hill, C.; Rykowski, R.; Galindo, R.; Aravamuthan, B. R.
10.1101/2024.02.01.578353 — neuroscience — Posted on 2024-02-02
4398 A lipidome Aging Clock shows Age Acceleration in individuals with Autism
Latumalea, D.; Unfried, M.; Barardo, D. G.; Gruber, J.; Kennedy, B. K.
10.1101/2024.02.01.578331 — neuroscience — Posted on 2024-02-02
4402 Bio-orthogonal Glycan Imaging of Culture Cells and Whole Animal C. elegans with Expansion Microscopy
Kuo, J. C.-H.; Colville, M. J.; Sorkin, M. R.; Kuo, J. L. K.; Huang, L.-T.; Thornlow, D. N.; Beacham, G. M.; Hollopeter, G.; DeLisa, M. P.; Alabi, C. A.; Paszek, M. J.
10.1101/2024.02.01.578333 — bioengineering — Posted on 2024-02-02
4406 Selection of different parameters to study epistatic effect between heat shock and slightly deleterious mutations in the most fragile stage of embryogenesis Cyprinus carpio L.
Kuzmin, A. V.; Skripskaya, V.; Lobanova, V.; Brodovaya, P.; Mukhitov, M.; Tarasova, A.; Popadin, K.; Mikhailova, A. G.; Vinogradov, E.; Mugue, N.; Balashov, D.
10.1101/2024.01.23.576732 — ecology — Posted on 2024-02-02
4407 Manipulation of the Nuclear Envelope-Associated Protein SLAPDuring Mammalian Brain Development Affects Cortical Lamination and Exploratory Behavior
Mestres, I.; Atabay, A.; Escolano, J.-C.; Arndt, S.; Schmidtke, K.; Einsiedel, M.; Patsonis, M.; Castro, L. A.; Yun, M.; Bernhardt, N.; Taubenberger, A. V.; Calegari, F.
10.1101/2024.01.31.578288 — developmental biology — Posted on 2024-02-02
4408 Role of Fibronectin in Postnatal Skeletal Development
Dinesh, N. E. H.; Baratang, N. P.; Rosseau, J.; Mohapatra, R.; Li, L.; Mahalingam, R.; Tiedemann, K.; Campeau, P. M.; Reinhardt, D. P.
10.1101/2024.02.01.578475 — developmental biology — Posted on 2024-02-02
4409 Stratification of viral shedding patterns in saliva of COVID-19 patients
Park, H.; Raiki, Y.; Iwanami, S.; Kim, K.; Ejima, K.; Nakamura, N.; Aihara, K.; Miyazaki, Y.; Umeyama, T.; Miyazawa, K.; Morita, T.; Watashi, K.; Brooke, C. B.; Ke, R.; Iwami, S.; Miyazaki, T.
10.1101/2024.01.30.578034 — microbiology — Posted on 2024-02-02
4411 Loss of CLN3 in microglia leads to impaired lipid metabolism and myelin turnover
Yasa, S.; Butz, E.; Colombo, A.; Chandrachud, U.; Montore, L.; Sheridan, S.; Mueller, S. A.; Lichtenthaler, S. F.; Tahirovic, S.; Cotman, S.
10.1101/2024.02.01.578018 — neuroscience — Posted on 2024-02-02
4412 Schizophrenia risk gene ZNF804A controls ribosome localization and synaptogenesis in developing human neurons
Sichlinger, L.; Wulf, M.; Dutan Polit, L.; Nasser, F.; Duarte, R. R.; Powell, T. R.; Marcus, K.; Vernon, A. C.; Srivastava, D. P.
10.1101/2024.02.02.578424 — neuroscience — Posted on 2024-02-02
4414 A Multimodal Characterization of Low-Dimensional Thalamocortical Structural Connectivity Patterns
John, A.; Hettwer, M. D.; Schaare, H. L.; Saberi, A.; Bayrak, S.; Wan, B.; Royer, J.; Bernhardt, B. C.; Valk, S. L.
10.1101/2024.02.01.578366 — neuroscience — Posted on 2024-02-02
4424 Temporal and spatial dynamics of Plasmodium falciparum clonal lineages in Guyana
Vanhove, M.; Schwabl, P.; Clementson, C.; Early, A. M.; Laws, M.; Anthony, F.; Florimond, C.; Mathieu, L.; James, K.; Knox, C.; Singh, N.; Buckee, C. O.; Musset, L.; Niles-Robin, R.; Cox, H.; Neafsey, D. E.
10.1101/2024.01.31.578156 — genomics — Posted on 2024-02-02
4425 Field evaluation of a volatile pyrethroid spatial repellent and etofenprox-treated clothing for outdoor protection against forest malaria vectors in Cambodia
Vajda, E. A.; Ross, A.; Doum, D.; Fairbanks, E.; Chitnis, N. A.; Hii, J.; Moore, S. J.; Richardson, J.; Macdonald, M.; Sovannaroth, S.; Kimheng, P.; McIver, D. J.; Tatarsky, A.; Lobo, N. F.
10.1101/2024.01.30.577940 — ecology — Posted on 2024-02-02
4427 Cefiderocol heteroresistance associated with mutations in TonB-dependent receptor genes in Pseudomonas aeruginosa of clinical origin
Egge, S. L.; Rizvi, S. A.; Simar, S. R.; Alcade-Rico, M.; Martinez, J. R.; Hanson, B. M.; Dinh, A. Q.; de Paula Baptista, R.; Tran, T. T.; Shelburne, S. A.; Munita, J. M.; Arias, C. A.; Hakki, M.; Miller, W. R.
10.1101/2024.01.30.578008 — microbiology — Posted on 2024-02-02
4428 IL-3-driven T cell-basophil crosstalk enhances anti-tumor immunity
Wei, J.; Mayberry, C. L.; Lv, X.; Hu, F.; Sears, J. D.; Khan, T.; Logan, N. A.; Wilson, J. J.; Chaussabel, D.; CHANG, C.-H.
10.1101/2024.02.01.578302 — immunology — Posted on 2024-02-02
4429 Decision-making processes in perceptual learning depend on effectors
Ivanov, V.; Manenti, G.; Plewe, S. S.; Kagan, I.; Schwiedrzik, C. M.
10.1101/2022.06.29.498152 — neuroscience — Posted on 2024-02-02
4430 KvS regulatory subunits confer drug resistance to Kv2 channels
Stewart, R. G.; Marquis, M. J.; Jo, S.; Ferns, M.; Sack, J. T.
10.1101/2024.01.31.578214 — neuroscience — Posted on 2024-02-02
4431 Microtubules ensure transport of vegetative nuclei and sperm cells by fine-tuning their home positions
Motomura, K.; Tsuchi, H.; Komojiri, M.; Matsumoto, A.; Sugi, N.; Susaki, D.; Takeda, A.; Kinoshita, T.; Maruyama, D.
10.1101/2024.01.31.578224 — plant biology — Posted on 2024-02-02
4433 The kinematics and aerodynamics of hinged wing of honeybees during takeoff
Li, Y.; Hao, Z.; Yang, B.; Gong, W.; Yin, B.; Wang, C.; Song, J.; Yin, L.
10.1101/2024.01.30.577934 — biophysics — Posted on 2024-02-02
4434 Seedless: On-the-fly pulse calculation for NMR experiments
Baldwin, A. J.; Jones, J.; Buchanan, C.; Karunanithy, G.; Casablancas-Antras, V.; Poh, A.; Davis, B. G.
10.1101/2024.01.31.578133 — biophysics — Posted on 2024-02-02
4441 Correlating fluorescence microscopy, optical and magnetic tweezers to study single chiral biopolymers, tested on DNA plectoneme formation dynamics
Shepherd, J.; Guilbaud, S.; Zhou, Z.; Howard, J.; Burman, M.; Schaefer, C.; Kerrigan, A.; Steele-King, C.; Noy, A.; Leake, M. C.
10.1101/2024.01.18.576226 — biophysics — Posted on 2024-02-02
4448 Using synchronized brain rhythms to bias memory-guided decisions
Stout, J. J.; George, A. E.; Kim, S.; Hallock, H. L.; Griffin, A. L.
10.1101/2023.04.02.535279 — neuroscience — Posted on 2024-02-02
4449 A Novel Therapeutic Approach using CXCR3 Blockade to Treat Immune Checkpoint Inhibitor-mediated Myocarditis
Huang, Y. V.; Lee, D.; Sun, Y.; Chou, H.; Xu, B.; Lin, Z.; Branche, C.; Bayer, A. L.; Waliany, S.; Neal, J.; Wakelee, H.; Witteles, R.; Nguyen, P.; Graves, E. E.; Alcaide, P.; Berry, G. J.; Wu, S. M.; Zhu, H.
10.1101/2024.01.30.576279 — cell biology — Posted on 2024-02-02
4450 Iron-sulfur cluster loss in mitochondrial CISD1 mediates PINK1 loss-of-function phenotypes
Bitar, S.; Baumann, T.; Weber, C.; Abusaada, M.; Rojas-Charry, L.; Ziegler, P.; Schettgen, T.; Randerath, I. E.; Venkataramani, V.; Michalke, B.; Arena, G.; Krueger, R.; Zhang, L.; Methner, A.
10.1101/2023.09.28.559909 — neuroscience — Posted on 2024-02-02
4456 Oct4 is a gatekeeper of epithelial identity by regulating cytoskeletal organization in skin keratinocytes
Christofidou, E.; Tomazou, M.; Voutouri, C.; Michael, C.; Stylianopoulos, T.; Spyrou, G. M.; Strati, K.
10.1101/2023.05.05.539557 — cell biology — Posted on 2024-02-02
4457 The regulation of polar flagella assembly in Pseudomonas putida
Pulido-Sanchez, M.; Leal-Morales, A.; Lopez-Sanchez, A.; Cava, F.; Govantes, F.
10.1101/2023.12.15.571843 — microbiology — Posted on 2024-02-02
4459 Rho GTPase signaling and mDia facilitate endocytosis via presynaptic actin
Oevel, K.; Hohensee, S.; Kumar, A.; Rosas-Brugada, I.; Bartolini, F.; Soykan, T.; Haucke, V.
10.1101/2023.10.12.561997 — neuroscience — Posted on 2024-02-02
4462 Specific amygdala and hippocampal subfield volumes in social anxiety disorder and their relation to clinical characteristics; an international mega-analysis
Ntwatwa, Z.; Spreckelmeyer, J.; Bas-Hoogendam, J. M.; van Honk, J.; Mufford, M.; Boraxbekk, C.-J.; Fouche, J.-P.; Frick, A.; Furmark, T.; Klumpp, H.; Lochner, C.; Luan Phan, K.; Mansson, K. N. T.; Pannekoek, N.; Peterburs, J.; Roelofs, K.; Roos, A.; Straube, T.; van Steenbergen, H.; Van Tol, M.-J.; Veltman, D. J.; van der Wee, N. J. A.; Stein, D. J.; Ipser, J.; Groenewold, N.
10.1101/2024.01.29.576056 — neuroscience — Posted on 2024-02-02
4463 A Comprehensive Human Embryogenesis Reference Tool using Single-Cell RNA-Sequencing Data
Zhao, C.; Plaza Reyes, A.; Schell, J. P.; Weltner, J.; Ortega, N.; Zheng, Y.; Bjorklund, A. K.; Baque-Vidal, L.; Sokka, J.; Trokovic, R.; Cox, B. J.; Rossant, J.; Fu, J.; Petropoulos, S.; Lanner, F.
10.1101/2021.05.07.442980 — developmental biology — Posted on 2024-02-02
4464 Rescaling protein-protein interactions improves Martini 3 for flexible proteins in solution
Thomasen, F. E.; Skaalum, T.; Kumar, A.; Srinivasan, S.; Vanni, S.; Lindorff-Larsen, K.
10.1101/2023.05.29.542689 — biophysics — Posted on 2024-02-01
4467 Scalable ultra-high-throughput single-cell chromatin and RNA sequencing reveals gene regulatory dynamics linking macrophage polarization to autoimmune disease
Lobato-Moreno, S.; Yildiz, U.; Claringbould, A.; Servaas, N. H.; Vlachou, E. P.; Arnold, C.; Bauersachs, H. G.; Campos-Fornes, V.; Prummel, K. D.; Noh, K. M.; Marttinen, M.; Zaugg, J. B.
10.1101/2023.12.26.573253 — genomics — Posted on 2024-02-02
4468 Tbx1 haploinsufficiency causes brain metabolic and behavioral anomalies in adult mice which are corrected by vitamin B12 treatment
Caterino, M.; Paris, D.; Torromino, G.; Costanzo, M.; Flore, G.; Tramice, A.; Golini, E.; Mandillo, S.; Cavezza, D.; Angelini, C.; Ruoppolo, M.; Motta, A.; De Leonibus, E.; Baldini, A.; Illingworth, E.; Lania, G.
10.1101/2024.02.01.578212 — genetics — Posted on 2024-02-01
4469 Decoding Huge Phage Diversity: A Taxonomic Classification of Lak Megaphages
Cook, R.; Crisci, M. A.; Pye, H. V.; Telatin, A.; Adriaenssens, E. M.; Santini, J. M.
10.1101/2024.02.01.578382 — microbiology — Posted on 2024-02-01
4472 Task Activation Results in Regional 13C-Lactate Signal Increase in the Human Brain
Uthayakumar, B.; Cappelletto, N. I. C.; Bragagnolo, N. D.; Chen, A. P.; Ma, N.; Perks, W. J.; Endre, R.; Tam, F.; Graham, S. J.; Heyn, C.; Keshari, K. R.; Soliman, H.; Cunningham, C. H.
10.1101/2024.02.01.577808 — neuroscience — Posted on 2024-02-01
4479 Opposing roles of resident and infiltrating immune cells in the defence against Legionella longbeachae via IL-18R/IFN-γ/ROS axis
Oberkircher, L. M.; Scheiding, V. M.; Rafeld, H. L.; Hanssen, E.; Hansen, J. N.; Fleischmann, M. J.; Kessler, N. M.; Pitsch, D.; Wachten, D.; Kastenmueller, W.; Brown, A. S.; Hartland, E.; van Driel, I. R.; Ng, G. Z.; Garbi, N.
10.1101/2024.01.31.578217 — immunology — Posted on 2024-02-01
4483 Challenging the Astral mass analyzer - going beyond 5200 proteins per single-cell at unseen quantitative accuracy to study cellular heterogeneity.
Bubis, J. A.; Arrey, T. N.; Damoc, E.; Delanghe, B.; Slovakova, J.; Sommer, T. M.; Kagawa, H.; Pichler, P.; Rivron, N. C.; Mechtler, K.; Matzinger, M.
10.1101/2024.02.01.578358 — biochemistry — Posted on 2024-02-01
4484 Target-aware Molecule Generation for Drug Design Using a Chemical Language Model
Xia, Y.; Wu, K.; Deng, P.; Liu, R.; Zhang, Y.; Guo, H.; Cui, Y.; Pei, Q.; Wu, L.; Xie, S.; Chen, S.; Lu, X.; Hu, S.; Wu, J.; Chan, C.-K.; Chen, S.; Zhou, L.; Yu, N.; Liu, H.; Guo, J.; Qin, T.; Liu, T.-Y.
10.1101/2024.01.08.574635 — biochemistry — Posted on 2024-02-01
4485 From sequence to molecules: Feature sequence-based genome mining uncovers the hidden diversity of bacterial siderophore pathways
Gu, S.; Shao, Y.; Rehm, K.; Bigler, L.; Zhang, D.; He, R.; Xu, R.; Shao, J.; Jousset, A.; Friman, V.-P.; Bian, X.; Wei, Z.; Kummerli, R.; Li, Z.
10.1101/2023.10.30.564663 — genomics — Posted on 2024-02-01
4486 Late stages of the Zika virus life cycle are impaired by a selective TRPML2 agonist
Schwickert, K. K.; Glitscher, M.; Bender, D.; Murra, R.; Schwickert, K.; Pfalzgraf, S.; Schirmeister, T.; Hellmich, U. A.; Hildt, E.
10.1101/2024.02.01.578205 — cell biology — Posted on 2024-02-01
4488 Topology-informed regulatory element collections coordinate cell identity gene expression programs
Lv, J.; Maher, K. A.; Veluchamy, A.; Kim, Y.; Dong, L.; Ju, B.; Valentine, V.; Valentine, M.; Burden, S.; Easton, J.; Pounds, S. B.; Abraham, B.
10.1101/2024.02.01.578210 — molecular biology — Posted on 2024-02-01
4490 NELF coordinates Pol II transcription termination and DNA replication initiation
Nakayama, C.; Daigaku, Y.; Aoi, Y.; Fang, Q.; Kimura, H.; Shilatifard, A.; Tellier, M.; Nojima, T.
10.1101/2024.01.31.578294 — molecular biology — Posted on 2024-02-01
4491 Programmable RNA writing with trans-splicing
Schmitt-Ulms, C.; Kayabolen, A.; Manero-Carranza, M.; Zhou, N.; Donnelly, K.; Nuccio, S. P.; Kato, K.; Nishimasu, H.; Gootenberg, J. S.; Abudayyeh, O. O.
10.1101/2024.01.31.578223 — molecular biology — Posted on 2024-02-01
4492 Towards understanding of allostery in MALT1: a possible role of interdomain motions as revealed by NMR and AlphaFold
Wallerstein, J.; Han, X.; Levkovets, M.; Lesovoy, D.; Malmodin, D.; Mirabello, C.; Wallner, B.; Sun, R.; Sandalova, T.; Agback, P.; Karlsson, G.; Achour, A.; Agback, T.; Orekhov, V.
10.1101/2024.02.01.578365 — molecular biology — Posted on 2024-02-01
4493 Neonatal enteroids absorb extracellular vesicles from human milk-fed infant digestive fluid
Yung, C.; Zhang, Y.; Kuhn, M.; Armstrong, R. J.; Olyaei, A.; Aloia, M.; Scottoline, B.; Andres, S. F.
10.1101/2023.09.03.556067 — molecular biology — Posted on 2024-02-01
4495 Alpha-synuclein overexpression can drive microbiome dysbiosis in mice
Sampson, T. R.; Wallen, Z. D.; Won, W.-J.; Standaert, D. G.; Payami, H.; Harms, A. S.
10.1101/2024.02.01.578464 — microbiology — Posted on 2024-02-01
4496 Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease
Zhou, X.; Shen, X.; Johnson, J.; Spakowicz, D.; Agnello, M.; Zhou, W.; Avina, M.; Honkala, A.; Chleilat, F.; Chen, S. J.; Cha, K.; Leopold, S.; Zhu, C.; Chen, L.; Lyu, L.; Hornburg, D.; Wu, S.; Zhang, X.; Jiang, C.; Jiang, L.; jiang, l.; Jian, R.; Brooks, A. W.; Wang, M.; Contrepois, K.; Gao, P.; Schussler-Fiorenza Rose, S. M.; Tran, T. D. B.; Nguyen, H.; Celli, A.; Hong, B.-Y.; Bautista, E. J.; Dorsett, Y.; Kavathas, P.; zhou, y.; Sodergren, E.; Weinstock, G. M.; Snyder, M. P.
10.1101/2024.02.01.577565 — microbiology — Posted on 2024-02-01
4497 The proteome is a terminal electron acceptor
Flamholz, A. I.; Goyal, A.; Fischer, W. W.; Newman, D. K.; Phillips, R.
10.1101/2024.01.31.578293 — microbiology — Posted on 2024-02-01
4498 Pediatric human nose organoids demonstrate greater susceptibility, epithelial responses, and cytotoxicity than adults during RSV infection.
Aloisio, G. M.; Nagaraj, D.; Murray, A. M.; Schultz, E. M.; McBride, T.; Aideyan, L.; Nicholson, E. G.; Henke, D.; Ferlic-Stark, L.; Rajan, A.; Kambal, A.; Johnson, H.; Mosa, E.; Stossi, F.; Blutt, S. E.; Piedra, P. A.; Avadhanula, V.
10.1101/2024.02.01.578466 — microbiology — Posted on 2024-02-01
4504 When no answer is better than a wrong answer: a causal perspective on batch effects
Bridgeford, E. W.; Powell, M.; Kiar, G.; Noble, S.; Chung, J.; Panda, S.; Lawrence, R.; Xu, T.; Milham, M.; Caffo, B.; Vogelstein, J. T.
10.1101/2021.09.03.458920 — neuroscience — Posted on 2024-02-01
4505 Marine heatwaves disrupt ecosystem structure and function via altered food webs and energy flux
Gomes, D. G. E.; Ruzicka, J. J.; Crozier, L. G.; Huff, D. D.; Brodeur, R. D.; Stewart, J. D.
10.1101/2023.08.11.553012 — systems biology — Posted on 2024-02-01
4506 DNA-Diffusion: Leveraging Generative Models for Controlling Chromatin Accessibility and Gene Expression via Synthetic Regulatory Elements
Ferreira DaSilva, L.; Senan, S.; Patel, Z. M.; Reddy, A. J.; Gabbita, S.; Nussbaum, Z.; Cordova, C. M. V.; Wenteler, A.; Weber, N.; Tunjic, T. M.; Khan, T. A.; Li, Z.; Smith, C. R.; Bejan, M.; Louis, L. K.; Cornejo, P.; Connell, W.; Wong, E. S.; Meuleman, W.; Pinello, L.
10.1101/2024.02.01.578352 — synthetic biology — Posted on 2024-02-01
4507 Ultra-sensitive water contaminant detection with transcription factor interfaced microcantilevers
Agarwal, D. K.; Lucci, T. J.; Jung, J. K.; Shekhawat, G. S.; Lucks, J. B.; Dravid, V. P. B.
10.1101/2024.02.01.578376 — synthetic biology — Posted on 2024-02-01
4508 Label-Free, Real-Time Monitoring of Cytochrome C Responses to Drugs in Microdissected Tumor Biopsies with a Multi-Well Aptasensor Platform
Nguyen, T. N. H.; Horowitz, L.; Krilov, T.; Lockhart, E.; Kenerson, H. L.; Yeung, R. S.; Arroyo-Curras, N.; Folch, A.
10.1101/2024.01.31.578278 — bioengineering — Posted on 2024-02-01
4510 Single-Stranded DNA with Internal Base Modifications Mediates Highly Efficient Gene Insertion in Primary Cells
Kanke, K. L.; Rayner, R. E.; Abel, E.; Venugopalan, A.; Suu, M.; Stack, J. T.; Nouri, R.; Guo, G.; Vetter, T. A.; Cormet-Boyaka, E.; Hester, M. E.; Vaidyanathan, S.
10.1101/2024.02.01.578476 — molecular biology — Posted on 2024-02-01
4511 Clostridioides difficile-mucus interactions encompass shifts in gene expression, metabolism, and biofilm formation
Furtado, K. L.; Plott, L. M.; Markovetz, M. R.; Powers, D. A.; Wang, H.; Hill, D. B.; Papin, J. A.; Allbritton, N. L.; Tamayo, R.
10.1101/2024.02.01.578425 — microbiology — Posted on 2024-02-01
4513 Visualizing the impact of disease-associated mutations on G protein-nucleotide interactions
Anazia, K.; Koenekoop, L.; Ferre, G.; Petracco, E.; Gutierrez-de-Teran, H.; Eddy, M.
10.1101/2024.01.30.578006 — biophysics — Posted on 2024-02-01
4514 Helicase-assisted continuous editing for programmable mutagenesis of endogenous genomes
Chen, X. D.; Chen, Z.; Wythes, G.; Zhang, Y.; Orr, B. C.; Sun, G.; Thao, K.; Vallurupalli, M.; Sun, J.; Borji, M.; Tkacik, E.; Chen, H.; Bernstein, B. E.; Chen, F.
10.1101/2024.02.01.577593 — genetics — Posted on 2024-02-01
4517 Mitochondrial Ca2+ efflux controls neuronal metabolism and long-term memory across species
Vishwanath, A. A.; Comyn, T.; Chintaluri, C.; Ramon-Duaso, C.; Fan, R.; Sivakumar, R.; Lopez-Manzaneda, M.; Preat, T.; Vogels, T. P.; Rangaraju, V.; Busquets-Garcia, A.; Placais, P.-Y.; Pavlowsky, A.; de Juan-Sanz, J.
10.1101/2024.02.01.578153 — neuroscience — Posted on 2024-02-01
4518 MicroRNAs and mRNA Regulatory Network of Parenchymal Hematoma after Endovascular Mechanical Reperfusion for Acute Ischemic Stroke in Rat
Zhuang, J.-K.; Huang, Z.-R.; Qin, W.; Li, C.-L.; Li, Q.; Xiang, C.; Tuo, Y.-H.; Liu, Z.; Chen, Q.-Y.; Shi, Z.-S.
10.1101/2024.02.01.578357 — neuroscience — Posted on 2024-02-01
4519 Systematic characterization of protein structural features of alternative splicing isoforms using AlphaFold 2
Yang, Y.; Xie, Y.; Li, Z.; Diala, C.; Ali, M.; Li, R.; Xu, Y.; Wu, A.; Kim, P.; Hosseini, S.-R.; Bi, E.; Zhao, H.; Zheng, W. J.
10.1101/2024.01.30.578053 — bioinformatics — Posted on 2024-02-01
4520 Reconstructing microvascular network skeletons from 3D images: what is the ground truth?
Walsh, C.; Berg, M.; West, H.; Holroyd, N. A.; Walker-Samuel, S.; Shipley, R. J.
10.1101/2024.02.01.578347 — bioengineering — Posted on 2024-02-01
4523 Trait prediction through computational intelligence and machine learning applied to soybean (Glycine max) breeding in shaded environments
da Silva Junior, A. C.; Costa, W. G. d.; Guimaraes, A. G.; Moura, W. M.; Bhering, L. L.; Cruz, C. D.; Batista, R. O.; Santos, J. B.; Campos, W. F.; Evaristo, A. B.
10.1101/2024.01.31.578252 — genetics — Posted on 2024-02-01
4527 Parallel evolution in mosquito vectors - a duplicated esterase locus is associated with resistance to pirimiphos-methyl in An. gambiae
Nagi, S. C.; Lucas, E. R.; Egyir-Yawson, A.; Essandoh, J.; Dadzie, S.; Chabi, J.; Djogbenou, L. S.; Medjigbodo, A. A.; Edi, C. V.; Ketoh, G.; Koudou, B. G.; Ashraf, F.; Clarkson, C. S.; Miles, A.; Weetman, D.; Donnelly, M. J.
10.1101/2024.02.01.578361 — evolutionary biology — Posted on 2024-02-01
4529 Environmental, host, and symbiont drivers of heat tolerance in a species complex of reef-building corals
Naugle, M. S.; Denis, H.; Mocellin, V. J. L.; Laffy, P. W.; Popovic, I.; Bay, L. K.; Howells, E. J.
10.1101/2024.01.31.575130 — ecology — Posted on 2024-02-01
4533 Global Release of Translational Repression Across Plasmodiums Host-to-Vector Transmission Event
Rios, K. T.; McGee, J. P.; Sebastian, A.; Moritz, R. L.; Feric, M.; Absalon, S.; Swearingen, K. E.; Lindner, S. E.
10.1101/2024.02.01.577866 — microbiology — Posted on 2024-02-01
4534 Depth-dependent scaling of axial distances in light microscopy
Loginov, S.; Boltje, D.; Hensgens, M. N. F.; Hoogenboom, J. P.; van der Wee, E.
10.1101/2024.01.31.578242 — biophysics — Posted on 2024-02-01
4536 Assessing computational predictions of antimicrobial resistance phenotypes from microbial genomes
Hu, K.; Meyer, F.; Deng, Z.-L.; Asgari, E.; Kuo, T.-H.; Münch, P. C.; McHardy, A. C.
10.1101/2024.01.31.578169 — bioinformatics — Posted on 2024-02-01
4538 The domesticated transposon protein L1TD1 associates with its ancestor L1 ORF1p to promote LINE-1 retrotransposition
Kavaklioglu, G.; Podhornik, A.; Vcelkova, T.; Marjanovic, J.; Beck, M. A.; Mair, T.; Miccolo, C.; Drino, A.; Egger, G.; Chiocca, S.; Modic, M.; Seiser, C.
10.1101/2024.02.01.577722 — genetics — Posted on 2024-02-01
4540 Glycan-induced structural activation softens the human papillomavirus capsid for entry through reduction of intercapsomere flexibility
Feng, Y.; van Bodegraven, D.; Kadek, A.; L.B. Munguira, I.; Soria-Martinez, L.; Nentwich, S.; Kavan, D.; Uetrecht, C.; Schelhaas, M.; Roos, W. H.
10.1101/2024.02.01.577804 — microbiology — Posted on 2024-02-01
4541 Synaptic plasticity in human thalamocortical assembloids
Patton, M. H.; Thomas, K. T.; Bayazitov, I. T.; Newman, K. D.; Kurtz, N. B.; Robinson, C. G.; Ramirez, C. A.; Trevisan, A. J.; Bikoff, J. B.; Peters, S. T.; Pruett-Miller, S. M.; Jiang, Y.; Schild, A. B.; Nityanandam, A.; Zakharenko, S. S.
10.1101/2024.02.01.578421 — neuroscience — Posted on 2024-02-01
4543 1-Aminocyclopropane-1-carboxylic acid oxidase determines the fate of ethylene biosynthesis in a tissue-specific way to fine-tune development and stress resilience
Houben, M.; Vaughan-Hirsch, J.; Pattyn, J.; Mou, W.; Roden, S.; Martinez, A. R.; Kabak, E.; Rodrigues, S.; Polko, A.; De Coninck, B.; Kieber, J. J.; Voet, A. R.; Van de Poel, B.
10.1101/2024.02.01.578397 — plant biology — Posted on 2024-02-01
4544 Somatic gene delivery for flexible in vivo modeling of high-risk sarcoma
Imle, R.; Blosel, D.; Kommoss, F.; Zhao, E.; Autry, R.; Blume, C.; Lupar, D.; Schmitt, L.; Winter, C.; Wagner, L.; Placke, S.; von Eicke, M.; Hertwig, M.; Peterziel, H.; Oehme, I.; Scheuerman, S.; Seitz, C.; Geyer, F.; Cidre-Aranaz, F.; Grunewald, T.; Vokuhl, C.; Chudasama, P.; Scholl, C.; Schmidt, C.; Gunther, P.; Sill, M.; Jones, K.; Pfister, S.; Banito, A.
10.1101/2024.01.30.577924 — cancer biology — Posted on 2024-02-01
4545 RNF43 is a gatekeeper for colitis-associated cancer
Dietl, A.; Ralser, A.; Taxauer, K.; Dregelies, T.; Sterlacci, W.; Stadler, M.; Olayo-Alarcon, R.; Margaryan, S.; Skerhut, M.; Groll, T.; Steiger, K.; Singh, D.; Li, X.; Oellinger, R.; Rad, R.; Janssen, K. P.; Mueller, C. L.; Vieth, M.; Gerhard, M.; Mejias Luque, R.
10.1101/2024.01.30.577936 — cancer biology — Posted on 2024-02-01
4546 Spatial Effects of Infiltrating T cells on Neighbouring Cancer Cells and Prognosis in Stage III CRC patients
Azimi, M.; Cho, S.; Bozkurt, E.; McDonough, E.; Kisakol, B.; Matveeva, A.; Salvucci, M.; Lindner, A.; Dussmann, H.; Shia, J.; McDade, S.; Longley, D. B.; Ginty, F.; Prehn, J. H. M.
10.1101/2024.01.30.577720 — cancer biology — Posted on 2024-02-01
4547 A shade-responsive microProtein in the Arabidopsis ATHB2 gene regulates elongation growth and root development
Edwards, A. K.; Chiurazzi, M. J.; Blaakmeer, A.; Vittozzi, Y.; Sharma, A.; Matton, S.; Kruusvee, V.; Straub, D.; Sessa, G.; Carabelli, M.; Morelli, G.; Wenkel, S.
10.1101/2024.02.01.578400 — plant biology — Posted on 2024-02-01
4548 Analysis arbuscular mycorrhizal fungi (AMF) community composition associated with alkaline saline sodic soils
Marquez, N.; Irazoqui, J. M.; Ciacci, M. B.; Amadio, A. F.; Fernandez, F. D.; Giachero, M. L.
10.1101/2024.02.01.578375 — plant biology — Posted on 2024-02-01
4549 In vivo targeted and deterministic single cell malignant transformation
Scerbo, P.; Tisserand, B.; Delagrange, M.; Debare, H.; Bensimon, D.; Ducos, B.
10.1101/2024.01.30.577941 — cancer biology — Posted on 2024-02-01
4550 Structurally-informed human interactome reveals proteome-wide perturbations by disease mutations
Xiong, D.; Qiu, Y.; Zhao, J.; Zhou, Y.; Lee, D.; Gupta, S.; Torres, M.; Lu, W.; Liang, S.; Kang, J. J.; Eng, C.; Loscalzo, J.; Cheng, F.; Yu, H.
10.1101/2023.04.24.538110 — bioinformatics — Posted on 2024-02-01
4552 The Circadian Neuropeptide PDF has Sexually Dimorphic Effects on Activity Rhythms
Iyer, A. R.; Scholz-Carlson, E.; Bell, E.; Biondi, G.; Richhariya, S.; Fernandez, M. d. l. P.
10.1101/2024.01.31.578273 — neuroscience — Posted on 2024-02-01
4553 Twilight length alters growth, flowering time, and clock function in Arabidopsis via LHY/CCA1
Mehta, D.; Scandola, S.; Kennedy, C.; Lummer, C.; Rodriguez Gallo, M. C.; Grubb, L. E.; Tan, M.; Scarpella, E.; Uhrig, R. G.
10.1101/2023.06.09.544111 — plant biology — Posted on 2024-02-01
4554 Cryo-EM structures of human cone visual pigments
Peng, Q.; Li, J.; Jiang, H.; Cheng, X.; Lu, Q.; Zhou, S.; Zhang, Y.; Lv, S.; Wan, S.; Yang, T.; Chen, Y.; Zhang, W.; Nan, W.; Che, T.; Li, Y.; Liao, H.; Zhang, J.
10.1101/2024.01.30.577689 — biophysics — Posted on 2024-02-01
4559 Age-related RPE Changes in Wildtype C57BL/6J Mice Between 2 and 32 Months
Shelton, D. A.; Gefke, I.; Liao, K.; Summers, V.; Yu, H.; Kim, Y.-K.; Getz, Y.; Ferdous, S.; Donaldson, K.; Papania, J.; Chrenek, M.; Boatright, J.; Nickerson, J.
10.1101/2024.01.30.574142 — cell biology — Posted on 2024-02-01
4560 Pyruvate metabolism dictates fibroblast sensitivity to GLS1 inhibition during fibrogenesis
Contento, G.; Wilson, J.-A. A.; Selvarajah, B.; Plate, M.; Guillotin, D.; Morales, V.; Trevisani, M.; Pitozzi, V.; Bianchi, K.; Chambers, R. C.
10.1101/2024.01.30.577965 — cell biology — Posted on 2024-02-01
4562 Chemokine expression profile of an innate granuloma
Amason, M. E.; Harvest, C. K.; Beatty, C. J.; Saban, D. R.; Miao, E. A.
10.1101/2024.01.30.577927 — immunology — Posted on 2024-02-01
4563 Mobile version of the Battery for the Assessment of Auditory Sensorimotor and Timing Abilities (BAASTA): Implementation and adult norms
Dalla Bella, S.; Foster, N.; Laflamme, H.; Zagala, A.; Kadi, M.; Komeilipoor, N.; Blais, M.; Rigoulot, S.; Kotz, S. A.
10.1101/2023.07.21.550031 — neuroscience — Posted on 2024-02-01
4567 Structural perspective on the design of selective DYRK1B inhibitors.
Grygier, P.; Pustelny, K.; Menezes, F.; Jemiola-Rzeminska, M.; Suder, P.; Dubin, G.; Czarna, A.
10.1101/2022.12.23.521429 — biochemistry — Posted on 2024-02-01
4570 CryoCycle your grids: Plunge vitrifying and reusing clipped grids to advance cryoEM democratization
Serbynovskyi, V.; Wang, J.; Chua, E. Y. D.; Ishemgulova, A.; Alink, L. M.; Budell, W. C.; Johnston, J. D.; Dubbeldam, C.; Gonzalez, F. A.; Rozovsky, S.; Eng, E. T.; de Marco, A.; Noble, A. J.
10.1101/2024.01.23.576763 — molecular biology — Posted on 2024-02-01
4572 A single pair of pharyngeal neurons functions as a commander to reject high salt in Drosophila melanogaster
Sang, J.; Dhakal, S.; Shrestha, B.; Nath, D. K.; Kim, Y.; Ganguly, A.; Montell, C.; Lee, Y.
10.1101/2023.10.17.562703 — neuroscience — Posted on 2024-02-01
4573 Neural correlates of memory in a naturalistic spatiotemporal context
Dougherty, M. R.; Chang, W.; Rudoler, J. H.; Katerman, B. S.; Halpern, D.; Bruska, J. P.; Diamond, N.; Kahana, M. J.
10.1101/2022.11.30.518606 — neuroscience — Posted on 2024-02-01
4574 The landscape of glial pathology and T-call response in Parkinson's substantia nigra
Jakubiak, K.; Paryani, F.; Kannan, A.; Lee, J.; Madden, N.; Li, J.; Chen, D.; Mahajan, A.; Xia, S.; Flowers, X.; Menon, V.; Sulzer, D.; Goldman, J. E.; Sims, P. A.; Al-Dalahmah, O.
10.1101/2024.01.08.574736 — neuroscience — Posted on 2024-02-01
4575 A dendritic mechanism for balancing synaptic flexibility and stability
Yaeger, C. E.; Vardalaki, D.; Zhang, Q.; Pham, T. L. D.; Brown, N. J.; Ji, N.; Harnett, M. T.
10.1101/2022.02.02.478840 — neuroscience — Posted on 2024-02-01
4578 MOSim: bulk and single-cell multi-layer regulatory network simulator
Monzo, C.; Arzalluz, A.; Martinez-Mira, C.; Conesa, A.; Tarazona, S.
10.1101/421834 — bioinformatics — Posted on 2024-02-01
4579 Fragment ion intensity prediction improves the identification rate of non-tryptic peptides in timsTOF
Adams, C.; Gabriel, W.; Laukens, K.; Picciani, M.; Wilhelm, M.; Bittremieux, W.; Boonen, K.
10.1101/2023.07.17.549401 — bioinformatics — Posted on 2024-02-01
4582 Cell-material interactions in 3D bioprinted plant cells
Madison, I.; Tahir, M. A.; Van den Broeck, L.; Phan, L.; Horn, T.; Sozzani, R.
10.1101/2024.01.30.578043 — cell biology — Posted on 2024-02-01
4588 Receptor kinase LecRK-I.9 regulates cell wall remodelling and signalling during lateral root formation in Arabidopsis
Bellande, K.; Roujol, D.; Chourre, J.; Le Gall, S.; Martinez, Y.; Jauneau, A.; Burlat, V.; JAMET, E.; Canut, H.
10.1101/2024.01.31.578125 — plant biology — Posted on 2024-02-01
4589 SlWRKY80 recruits SlHDA1 to regulates the tomato fruit ripening and color transformation
Hu, X.; Shang, C.; Chen, G.; Liu, X.; zheng, H.; Li, G.; Wang, J.; Hu, S.; Li, Z.
10.1101/2024.01.31.578225 — plant biology — Posted on 2024-02-01
4599 Targeting PD-L1 in solid cancer with myeloid cells expressing a CAR-like immune receptor
Chen, K. M.; Grun, D.; Gautier, B.; Venkatesha, S.; Maddox, M.; Zhang, A.-H.; Andersen, P.
10.1101/2024.01.29.577873 — immunology — Posted on 2024-02-01
4601 Early body weight gain in TALLYHO/JngJ mice predicts adult diabetic phenotype, mimicking childhood obesity
Hastreiter, S.; Hoffmann, S.; Richter, K.; Irmler, M.; Gerlini, R.; Fuchs, H.; Gailus-Dumer, V.; Gailus-Durner, V.; Korner, A.; Hrabe de Angelis, M.; Beckers, J.
10.1101/2024.01.29.577705 — physiology — Posted on 2024-02-01
4603 Accelerated Hematopoietic Stem Cell Aging in Space
Pham, J.; Isquith, J.; Balaian, L.; Ladel, L.; Nandi, S. P.; Mack, K.; van der Werf, I.; Klacking, E.; Ruiz, A.; Mays, D.; Gamble, P.; Giza, S.; Janowitz, J.; Nienaber, T.; Mishra, T.; Kulidjian, A.; Stoudemire, J.; Snyder, M. P.; Clements, T.; Muotri, A. R.; Morris, S. R.; Whisenant, T.; Alexandrov, L. B.; Jamieson, C. H. M.
10.1101/2024.01.28.577076 — cancer biology — Posted on 2024-02-01
4605 Divergent Folding-Mediated Epistasis Among Unstable Membrane Protein Variants
Chamness, L. M.; Kuntz, C. P.; McKee, A. G.; Penn, W. D.; Hemmerich, C. M.; Rusch, D. B.; Woods, H.; Dyotima, ; Meiler, J.; Schlebach, J. P.
10.1101/2023.08.25.554866 — biochemistry — Posted on 2024-02-01
4606 A "torn bag mechanism" of small extracellular vesicle release via limiting membrane rupture of en bloc released amphisomes (amphiectosomes)
Visnovitz, T.; Lenzinger, D.; Koncz, A.; Vizi, P. M.; Barkai, T.; Vukman, K. V.; Galinsoga, A.; Nemeth, K.; Fletcher, K.; Komlosi, Z. I.; Lorincz, P.; Valcz, G.; BUZAS, E. I.
10.1101/2024.01.30.578035 — cell biology — Posted on 2024-02-01
4608 Microbiota encoded fatty-acid metabolism expands tuft cells to protect tissues homeostasis during Clostridioides difficile infection in the large intestine
Kellogg, T. D.; Ceglia, S.; Mortzfeld, B. M.; Zeamer, A. L.; Foley, S. E.; Ward, D.; Bhattarai, S. K.; McCormick, B. A.; Reboldi, A.; Bucci, V.
10.1101/2024.01.29.574039 — immunology — Posted on 2024-02-01
4610 Brain white matter pathways of resilience to chronic back pain: a multisite validation
Misic, M.; Lee, N.; Zidda, F.; Sohn, K.; Usai, K.; Löffler, M.; Uddin, N.; Farooqi, A.; Schifitto, G.; Zhang, Z.; Nees, F.; Geha, P.; Flor, H.
10.1101/2024.01.30.578024 — neuroscience — Posted on 2024-02-01
4611 Behavioural responses to acute warming precede critical shifts in the cellular and physiological thermal stress responses in fish
Durhack, T. C.; Thorstensen, M. J.; Mackey, T. E.; Aminot, M.; Lawrence, M. J.; Audet, C.; Enders, E. C.; Jeffries, K. M.
10.1101/2024.01.29.577477 — physiology — Posted on 2024-02-01
4612 Cooperativity of c-MYC with Krüppel-Like Factor 6 Splice Variant 1 induces phenotypic plasticity and promotes prostate cancer progression and metastasis
Izadmehr, S.; Fernandez-Hernandez, H.; Wiredja, D.; Kirschenbaum, A.; Lee-Poturalski, C.; Tavassoli, P.; Yao, S.; Schlatzer, D.; Hoon, D.; DiFeo, A.; Levine, A. C.; Mosquera, J.-M.; Galsky, M. D.; Cordon-Cardo, C.; Narla, G.
10.1101/2024.01.30.577982 — cancer biology — Posted on 2024-02-01
4613 Ensemble learning and ground-truth validation of synaptic connectivity inferred from spike trains
Donner, C.; Bartram, J.; Hornauer, P.; Kim, T.; Roqueiro, D.; Hierlemann, A.; Obozinski, G.; Schroeter, M.
10.1101/2024.02.01.578336 — neuroscience — Posted on 2024-02-01
4615 Dissociating endogenous and exogenous delta activity during natural speech comprehension
Chalas, N.; Meyer, L.; Lo, C.-W.; Park, H.; Kluger, D. S.; Abbasi, O.; Kayser, C.; Nitsch, R.; Gross, J.
10.1101/2024.02.01.578181 — neuroscience — Posted on 2024-02-01
4616 Upregulated cholesterol biosynthesis facilitates the survival of methylation-retaining AML cells following decitabine treatment.
Bond, D. R.; Burnard, S. M.; Uddipto, K.; Hunt, K. V.; Harvey, B. M.; Steffens Reinhardt, L.; Lawlor-O'Neill, C.; Roper, E. A.; Humphries, S.; Murray, H. C.; Bowden, N. A.; Enjeti, A. K.; Verrills, N. M.; Riveros, C.; Le Cao, K.-A.; Lee, H. J.
10.1101/2024.01.30.577864 — cancer biology — Posted on 2024-02-01
4617 Discovery and Characterization of Terpene Synthases Powered by Machine Learning
Samusevich, R.; Hebra, T.; Bushuiev, R.; Bushuiev, A.; Chatpatanasiri, R.; Kulhanek, J.; Calounova, T.; Perkovic, M.; Engst, M.; Tajovska, A.; Sivic, J.; Pluskal, T.
10.1101/2024.01.29.577750 — biochemistry — Posted on 2024-02-01
4618 Cycling reduces the entropy of neuronal activity in the human adult cortex
Ferre, I. B. S.; Corso, G.; dos Santos Lima, G. Z.; Lopes, S. R.; Leocadio-Miguel, M. A.; Franca, L.; de Lima Prado, T.; Araujo, J. F.
10.1101/2024.01.31.578253 — neuroscience — Posted on 2024-02-01
4620 Treacle's ability to form liquid phase condensates is essential for nucleolar fibrillar center assembly, efficient rRNA transcription and processing, and rRNA gene repair.
Velichko, A. K.; Kovina, A. P.; Luzhin, A. V.; Petrova, N. V.; Deriglazov, D. A.; Kazakov, E. P.; Kireev, I. I.; Razin, S. V.; Kantidze, O.
10.1101/2023.05.11.540311 — cell biology — Posted on 2024-02-01
4621 Developmental effect of RASopathy mutations on neuronal network activity on a chip
Weiss, E.-M.; Guhathakurta, D.; Petruskova, A.; Hundrup, V.; Zenker, M.; Fejtova, A.
10.1101/2023.09.20.558464 — neuroscience — Posted on 2024-02-01
4622 C4 Grasses Employ Distinct Strategies to Acclimate Rubisco Activase to Heat Stress
Stainbrook, S. C.; Aubuchon, L. N.; Chen, A.; Johnson, E.; Si, A.; Walton, L.; Ahrendt, A.; Strenkert, D.; Jez, J. M.
10.1101/2022.08.24.505184 — plant biology — Posted on 2024-02-01
4625 The Phage-shock-protein (PSP) Envelope Stress Response:Discovery of Novel Partners and Evolutionary History
Ravi, J.; Anantharaman, V.; Chen, S. Z.; Brenner, E. P.; Datta, P.; Aravind, L.; Gennaro, M. L.
10.1101/2020.09.24.301986 — bioinformatics — Posted on 2024-02-01
4627 Characterization of N-glycosylation and its Functional Role in SIDT1-Mediated RNA Uptake
Yang, T.; Xiao, H.; Chen, X.; Zheng, L.; Guo, H.; Wang, J.; Jiang, X.; Zhang, C.-Y.; Yang, F.; Ji, X.
10.1101/2023.08.01.551569 — biochemistry — Posted on 2024-02-01
4628 Genetic similarity between relatives provides evidence on the presence and history of assortative mating
Sunde, H. F.; Eftedal, N. H.; Cheesman, R.; Corfield, E. C.; Kleppesto, T. H.; Seierstad, A. C.; Ystrom, E.; Eilertsen, E. M.; Torvik, F. A.
10.1101/2023.06.27.546663 — genetics — Posted on 2024-02-01
4634 Rbm8a deficiency causes hematopoietic defects by modulating Wnt/PCP signaling
Kocere, A.; Chiavacci, E.; Soneson, C.; Wells, H. H.; Mendez-Acevedo, K. M.; MacGowan, J. S.; Jacobson, S. T.; Hiltabidle, M. S.; Raghunath, A.; Shavit, J. A.; Panakova, D.; Williams, M. L. K.; Robinson, M. D.; Mosimann, C.; Burger, A.
10.1101/2023.04.12.536513 — developmental biology — Posted on 2024-02-01
4636 Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming
Holman, C. D.; Sakers, A. P.; Calhoun, R. P.; Cheng, L.; Fein, E. C.; Jacobs, C.; Tsai, L.; Rosen, E. D.; Seale, P.
10.1101/2023.03.20.533514 — developmental biology — Posted on 2024-02-01
4637 Cell cycle variants during Drosophila accessory gland development
Box, A. M.; Ramesh, N. A.; Nandakumar, S.; Church, S. J.; Prasad, D.; Afrakhteh, A.; Taichman, R. S.; Buttitta, L.
10.1101/719013 — developmental biology — Posted on 2024-02-01
4639 foxe1 mutant zebrafish show indications of a hypothyroid phenotype and increased sensitivity to ethanol for craniofacial malformations
Raterman, S. T.; Wagner, F. A. D. T. G.; Zethof, J.; Cuijpers, V.; Klaren, P. H. M.; Metz, J. R.; Von den Hoff, J. W.
10.1101/2024.01.31.578204 — developmental biology — Posted on 2024-02-01
4641 Low Shear in Short-Term Impacts Endothelial Cell Traction and Alignment in Long-Term
Chandurkar, M. K.; Mittal, N.; Royer-Weeden, S. P.; Lehmann, S. D.; Rho, Y.; Han, S. J.
10.1101/2023.09.20.558732 — cell biology — Posted on 2024-02-01
4643 Collaborative Cross mice have diverse phenotypic responses to infection with Methicillin-resistant Staphylococcus aureus USA300
Nagarajan, A.; Scoggin, K.; Gupta, J.; Aminian, M.; Adams, L. G.; Kirby, M.; threadgill, D.; Andrews-Polymenis, H. L.
10.1101/2023.07.12.548741 — microbiology — Posted on 2024-02-01
4644 Tryptophan Metabolites And Their Predicted Microbial Sources In Fecal Samples From Healthy Individuals
Chappell, C. L.; Hoffman, K. L.; Lorenzi, P. L.; Tan, L.; Petrosino, J.; Gibbs, R.; Muzny, D.; Doddapaneni, H.; Ross, M. C.; Menon, V. K.; Surathu, A.; Javornik Cregeen, S. J.; Reyes, A. G.; Okhuysen, P. C.
10.1101/2023.12.20.572622 — microbiology — Posted on 2024-02-01
4645 A transmission bottleneck for malaria? Quantification of sporozoite expelling by Anopheles mosquitoes infected with laboratory and naturally circulating P. falciparum gametocytes
Andolina, C.; Graumans, W.; Guelbeogo, M.; Gemert, G.-J. v.; Ramjith, J.; Harouna, S.; Soumanaba, Z.; Stoter, R.; van de Vegte-Bolmer, M.; Pangos, M.; Sinnis, P.; Collins, K.; Staedke, S.; Tiono, A.; Drakeley, C.; Lanke, K.; Bousema, T.
10.1101/2023.08.03.551751 — microbiology — Posted on 2024-02-01
4648 Candida albicans' inorganic phosphate transport and evolutionary adaptation to phosphate scarcity
Acosta-Zaldivar, M.; Qi, W.; Mishra, A.; Roy, U.; King, W. R.; Patton-Vogt, J.; Anderson, M. Z.; Kohler, J. R.
10.1101/2024.01.29.577887 — microbiology — Posted on 2024-02-01
4649 Viral gene drive spread during herpes simplex virus 1 infection in mice
Walter, M.; Haick, A. K.; Riley, R.; Massa, P. A.; Strongin, D. E.; Klouser, L. M.; Loprieno, M. A.; Stensland, L.; Santo, T. K.; Aubert, M.; Taylor, M. P.; Jerome, K. R.; Verdin, E.
10.1101/2023.12.07.570711 — microbiology — Posted on 2024-02-01
4650 Transposable elements regulate thymus development and function
Larouche, J.-D.; Laumont, C. M.; Trofimov, A.; Vincent, K.; Hesnard, L.; Brochu, S.; Cote, C.; Humeau, J.; Bonneil, E.; Lanoix, J.; Durette, C.; Gendron, P.; Laverdure, J.-P.; Richie, E. R.; Lemieux, S.; Thibault, P.; Perreault, C.
10.1101/2023.07.12.548732 — immunology — Posted on 2024-02-01
4651 Sex differences in brain-behavior relationships in the first two years of life
Fenske, S. J.; Liu, J.; Chen, H.; Diniz, M.; Stephens, R.; Cornea, E.; Gilmore, J. H. J.; Gao, W.
10.1101/2024.01.31.578147 — neuroscience — Posted on 2024-02-01
4652 Functionally distinct subdomains of dopamine in the hippocampus
Mehra, M.; Molina, G. E.; Islam, M. T.; Dhanerawala, Z.; Bano, E.; Han, E.
10.1101/2024.01.31.578232 — neuroscience — Posted on 2024-02-01
4655 Cortical acetylcholine dynamics are predicted by cholinergic axon activity and behavior state
Neyhart, E.; Zhou, N.; Munn, B. R.; Law, R. G.; Smith, C.; Mridha, Z. H.; Blanco, F. A.; Li, G.; Li, Y.; McGinley, M. J.; Shine, J. M.; Reimer, J.
10.1101/2023.11.14.567116 — neuroscience — Posted on 2024-02-01
4657 ARX regulates interneuron subtype differentiation and migration
Cho, G.; Lim, Y.; Akula, S. K.; Myers, A. K.; Chen, C.; Rafael, K.; Walsh, C. A.; Golden, J. A.
10.1101/2024.01.31.578282 — neuroscience — Posted on 2024-02-01
4659 Building compositional tasks with shared neural subspaces
Tafazoli, S.; Bouchacourt, F.; Ardalan, A.; Markov, N. T.; Uchimura, M.; Gomes Mattar, M. G.; Daw, N. D.; Buschman, T. J.
10.1101/2024.01.31.578263 — neuroscience — Posted on 2024-02-01
4660 Using normative models pre-trained on cross-sectional data to evaluate longitudinal changes in neuroimaging data
Rehak Buckova, B.; Fraza, C.; Rehak, R.; Kolenic, M.; Beckmann, C.; Spaniel, F.; Marquand, A.; Hlinka, J.
10.1101/2023.06.09.544217 — neuroscience — Posted on 2024-02-01
4661 Distributed fMRI dynamics predict distinct EEG rhythms across sleep and wakefulness
Jacob, L. P. L.; Bailes, S. M.; Williams, S. D.; Stringer, C.; Lewis, L. D.
10.1101/2024.01.29.577429 — neuroscience — Posted on 2024-02-01
4664 Laminin-defined Mechanical Status Modulates Retinal Pigment Epithelium Functionality
Kozyrina, A. N.; Piskova, T.; Semeraro, F.; Doolaar, I.; Prapty, T.; Haraszti, T.; Hubert, M.; Windoffer, R.; Leube, R. E.; Smith, A.-S.; Di Russo, J.
10.1101/2023.02.24.529913 — biophysics — Posted on 2024-02-01