Channel:  The Howard Hughes Medical Institute (HHMI)

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Engineered caspases directly rewire mutant Ras to cell death
Moeller, L., Lu, A. C., Ho, K., Zhang, E., Elowitz, M. B.
10.64898/2026.08.06.743376 — Posted: 2026-08-07
Single-cell multiomic mapping of genetic predisposition to childhood B-cell acute lymphoblastic leukemia
Lee, A. J., Neehus, A.-L., Wahlster, L., Agarwal, G., Weng, C., Zhang, A., Liu, T., Shelton, S., Ye, T., Volpe, L. d., Cohn, O., Poeschla, M., King, E., Ha, S. A., Turvey, A. K., Chiang, C. W. K., Wiemels, J. L., de Smith, A. J., Sankaran, V. G.
10.64898/2026.08.06.743308 — Posted: 2026-08-07
tinyRNA-seq: An optimized approach to sequencing tiny RNAs and primitive RNA genomes
Colville, B. W. F., Zhao, J., Hade, L., Szostak, J. W.
10.64898/2026.08.06.743385 — Posted: 2026-08-07
Connectomic Analysis of Mitochondria in the Central Brain of Drosophila
Longden, K. D., Rivlin, P. K., Januszewski, M., Neace, E., Scheffer, L. K., Ordish, C., Clements, J., Phillips, E., Smith, N., Takemura, S., Umayam, L., Walsh, C., Yakal, E. A., Musial, T. F., Devine, M. J., Reiser, M. B., Plaza, S. M., Berg, S.
10.1101/2024.04.21.590464 — Posted: 2026-08-07
A functional genomics screen of human B-cell differentiation reveals convergent mechanisms of inherited childhood leukemia predisposition
Wahlster, L., Neehus, A.-L., Lee, A. J., Mazumder, S., Mehrzad, P., Black, S., Messa, L., Liu, T., Wang, C., Weng, C., Caulier, A., Pak, J., Fleming, T., Antoszewski, M., Zhang, A., Ha, S. A., Oleaga-Quintas, C., de Smith, A. J., Sankaran, V. G.
10.64898/2026.08.06.743305 — Posted: 2026-08-07
Sequence adaptations satisfy the constraints of mitochondrial membrane protein evolution
Yadav, T., Borowsky, J., Narbona-Perez, A. J., Soni, B., Cunningham, C. N., Carrington, J., Grabe, M., Rutter, J.
10.64898/2026.08.04.742770 — Posted: 2026-08-07
Protective pan-betacoronavirus neutralizing antibodies by vaccination
Zhou, P., Feng, Z., He, W.-t., Zhu, Y., Yuan, M., Li, X., Zhang, Y., Vo, L., Capozzola, T., Callaghan, S., Mishra, N., Avillion, G., Dueker, K., Liang, B., Roy Chowdhury, R., Nedellec, R., Lee, W.-H., Allen, J. D., Walsh, A., Melo, M., McAnarney, E. T., Kumar, N. A., Rinaldi, W., Ferguson, M., Crispin, M. M., Ward, A. B., Irvine, D. J., Alameh, M.-G., Weissman, D., Baric, R., Gralinski, L. E., Wilson, I., Burton, D. R., Andrabi, R.
10.64898/2026.08.06.743418 — Posted: 2026-08-07
The Phantom of the PCR: detection and consequences of spurious UMIs in mainstream RNA sequencing
Sugino, K., Lee, T.
10.64898/2026.08.01.742199 — Posted: 2026-08-06
Tobacco smoke-induced DNA adducts sensitize genomes to APOBEC mutagenesis and carcinogenesis through nucleotide excision repair
Durfee, C., Stefanovska, B., Wu, R., Cordoba-Caballero, J., Ibrahim, M. A., Carpenter, M. A., Liu, L., Nandi, S. P., Argyris, P. P., Bielo, L. B., Li, E. C. L., Temiz, N. A., Zhou, Y., Bergstrom, E. N., Mullally, C., Wang, Y., Liu, X., Barreto Duran, E., Troness, B., Proehl, J., Gupta, H., York, A., Vogel, R. I., Wells, J. M., Steele, C. D., Stuewe, I., Muldoon, D., Woo, J., Donoghue, M. T. A., Lindsey-Boltz, L. A., Sancar, A., Bandlamudi, C., Chandarlapaty, S., Yang, W., Malkova, A., Diaz-Gay, M., Alexandrov, L. B., Harris, R.
10.1101/2025.01.18.633716 — Posted: 2026-08-06
Cohesin loading at regulatory elements shapes 3D genome folding during erythropoiesis
Ramanathan, V., Guo, C.-J., Nagano, M., Goel, V. Y., Hong, C. K., Swett, A. D., Caulier, A., King, E., Tothova, Z., Sankaran, V. G., Hansen, A. S.
10.64898/2026.08.02.741886 — Posted: 2026-08-06

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