Channel: Brown University

This collection includes bioRxiv and medRxiv papers from authors at Brown University.

1292 Articles

CaBLAM! A high-contrast bioluminescent Ca2+ indicator derived from an engineered Oplophorus gracilirostris luciferase

Lambert, G. G., Crespo, E. L., Murphy, J., Turner, K., Gershowitz, E., Cunningham, M., Boassa, D., Luong, S., Celinskis, D., Allen, J. J., Venn, S., Zhu, Y., Karadas, M., Chen, J., Marisca, R., Gelnaw, H., Nguyen, D. K., Hu, J., Sprecher, B. N., Tree, M. O., Orcutt, R., Heydari, D., Bell, A. B., Torreblanca-Zanca, A., Hakimi, A., Czopka, T., Shoham, S., Nagel, K. I., Schoppik, D., Andrade, A., Lipscombe, D., Moore, C. I., Hochgeschwender, U., Shaner, N. C.

10.1101/2023.06.25.546478 — Posted: 2025-07-26

TGF-β Coordinates Alanine Synthesis and Import for Myofibroblast Differentiation in Pulmonary Fibrosis

Li, F., Vigder, N., Ziehr, D., Kamiya, M., Nguyen, H. N., Steinhauser, M., Kim, E. Y., Oldham, W. M.

10.1101/2025.07.23.666333 — Posted: 2025-07-24

Early pregnancy health behaviors, adverse pregnancy outcomes, and maternal blood pressure after pregnancy

Kozai, A., Barone Gibbs, B., Levine, L. D., Lane, A. D., Ray, M., Grobman, W., Greenland, P., Hoffman, M. K., Bairey Merz, C. N. K., Zee, P. C., Mims, L., Cameron, N. A., Saade, G., Silver, R. M., Bello, N. A., Miller, E. C., Reddy, U. M., Chung, J. H., Whitaker, K. M., Catov, J. M.

10.1101/2024.12.27.24319672 — Posted: 2025-07-24

Artemisinin Partial Resistance Mutations in Zanzibar and Tanzania Suggest Regional Spread and African Origins, 2023

Connelly, S. V., Muller, J. G., Ali, M., Ngasala, B. E., Hassan, W., Mohamed, B., Thwai, K. L., Sadler, J. M., Marglous, J., Fola, A. A., Zacharia, A., Shija, S. J., Mohammed, S., Msolo, D. C., Said, H., Peter, E. E., Odas, M., Rutha, I. J., Nwange, M., Niare, K., Ruybal-Pesantez, S., Verity, R., Crudale, R., Goel, V., Choloi, B. B., Bjorkman, A., Bailey, J. A., Lin, J. T., Juliano, J. J.

10.1101/2025.03.22.25323829 — Posted: 2025-07-23

Understanding Malaria Treatment Adherence in Rwanda: Implications for Artemisinin Resistance

Gashema, P., Jordan, A. M., Saramba, E., Wernsman Young, N. M., Iradukunda, P. G., Karema, C., Mazarati, J.-B., Juliano, J. J., Bailey, J. A., Banek, K.

10.1101/2025.07.22.25331991 — Posted: 2025-07-23

Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries.

Huerta-Chagoya, A., Kim, J., Mandla, R., Lu, Y., Suzuki, K., Petty, L. E., Ng, H. K., Choi, J., Lee, S., Rout, M., Lin, K., Adair, L. S., Adeyemo, A., Ahsan, H., Akiyama, M., An, P., Anand, S. S., Becker, D. M., Bertoni, A. G., Bian, Z., Bielak, L. F., Blangero, J., Boehnke, M., Bottinger, E. P., Bowden, D. W., Bragg, F., Brody, J. A., Buchanan, T. A., Cade, B. E., Chai, J.-F., Chambers, J. C., Chandak, G. R., Chang, L.-C., Chang, K.-M., Chee, M.-L., Chen, C.-H., Chen, Y.-T., Chen, Z., Chen, Y.-D. I., Chen, J., Chen, G., Chen, S.-H., Chen, W.-M., Cheng, C.-Y., Cho, Y. S., Choi, H. S., Chuang

10.1101/2025.07.21.25331778 — Posted: 2025-07-23

Evaluation of Amyloid Removal as a Surrogate for Cognitive Decline: Pilot Analysis in Individual-Level Data from the A4 Study of Solanezumab

Ackley, S., Flanders, M., Murchland, A., Chen, R., Wang, J., Shah, S. J., Huey, E. D., Glymour, M. M.

10.1101/2025.07.21.25331942 — Posted: 2025-07-22

Blood-tumor barrier organoids recapitulate glioblastoma microenvironment and enable high-throughput modeling of therapeutic delivery

Zhuang, P., Scott, B., Gao, S., Meng, W.-M., Yin, R., Nie, X., Gaiaschi, L., Lawler, S. E., Lamfers, M. L., Bei, F., Cho, C.-F.

10.1101/2024.11.11.622979 — Posted: 2025-07-22

Programmable microparticles rewire CAR signaling to enable super-physiological expansion of human T cells in vitro

Zeng, Q., Flemming, L., Chen, Y., Mazumder, T., Hammerlindl, H., Allen, G. M., Almeida, R., Williams, J. Z., Hernandez-Lopez, R. A., Eyquem, J., Ye, C. J., Lim, W. A., Tang, Q., Desai, T., Huang, X.

10.1101/2025.07.17.665438 — Posted: 2025-07-22

Single-cell transcriptional changes across the blood stages of artemisinin-resistant K13580Y Plasmodium falciparum upon dihydroartemisinin exposure

Oduor, C. I., Connelly, S. V., Cunningham, C., Petrow, I., Rustamzade, N., Zuromski, J., Chin, D. M., Nixon, C. P., Kurtis, J. D., Juliano, J. J., Bailey, J. A.

10.1101/2023.12.06.570387 — Posted: 2025-07-20

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