Channel: University of Iowa

This collection includes bioRxiv and medRxiv papers from authors at University of Iowa.

1178 Articles

Primary Central Nervous System Lymphoma Tumor Biopsies Show Heterogeneity in Gene Expression Profiles, Genetic Subtypes, and in vitro Drug Sensitivity to Kinase Inhibitors

Zhu, Y. X., Wong, J. C., Hilal, T., Maguire, A., Ocal, J., Zellner, K., Chen, J., Link, B. K., Habermann, T. M., Maurer, M. J., Cerhan, J. R., Johnston, P. B., Feldman, A. L., Scott, D. W., Rosenthal, A., Rimsza, L.

10.1101/2024.11.11.24316310 — Posted: 2024-11-15

HLA-A*02:01 allele is associated with decreased risk and a longer survival in pancreatic cancer: Results from an exhaustive analysis of the HLA variation in PDAC

Langtry, A., Rabadan, R., Alonso, L., van Eijck, C., Macarulla, T., Lawlor, R., Carrato, A., Alvarez-Gallego, R., Iglesias, M., Molero, X., Lohr, J. M., Michalski, C., Perea, J., ORorke, M., Barber, V., Tardon, A., Farre, A., Munoz-Bellvis, L., Crnogorac-Jurcevic, T., Dominguez-Munoz, E., Gress, T., Greenhalf, W., Sharp, L., Sabroso-Lasa, S., Filip, I., Strijk, G., Castet, F., Balsells, J., Costello, E., Kleeff, J., Kong, B., Mora, J., ODriscoll, D., Scarpa, A., Ye, W., Real, F. X., Malats, N., Lopez de Maturana, E.

10.1101/2024.08.29.24312704 — Posted: 2024-11-14

Peripheral CGRP engages brain-wide electrical network activity of migraine

Johnson, M. S., Eberle, M., Hultman, I., Zhang, X., Filali, Y., Hing, B., Jimenez, A., Matkovich, M., Adegboyo, A., Velamuri, R., Miller, J., Chan, K.-S., Srivastava, S., Hultman, R.

10.1101/2024.11.14.622885 — Posted: 2024-11-14

Acute Inhibition of Adipose Triglyceride Lipase by NG497 Dysregulates Insulin and Glucagon Secretion from Human Islets

Kim, L., Liu, S., Richtsmeier, S., Gorniak, M., Vikram, A., Imai, Y.

10.1101/2024.11.11.623085 — Posted: 2024-11-13

Axonal organelle buildup from loss of AP-4 complex function causes exacerbation of amyloid plaque pathology and gliosis in Alzheimers disease mouse model

Orlowski, A., Karippaparambil, J., Paumier, J.-M., Ghanta, S., Pallares, E., Chandran, R., Edmison, D., Tandukar, J., Gao, R., Gowrishankar, S.

10.1101/2024.03.31.587499 — Posted: 2024-11-11

Perilipin 5 Phosphorylation is Dispensable for Upregulation of Hepatic Lipid Metabolism Genes upon Fasting but Required for Insulin Receptor Substrate 2 Expression in Male Mice

Bovee, C., Grandgenett, R., Trevino, M., Dutta, S., Peachee, S., Kopriva, S., Haider, F., Liu, S., Bhardwaj, G., Penniman, C., O'Neill, B., Imai, Y.

10.1101/2024.11.09.622792 — Posted: 2024-11-09

Genetic and pharmacologic alterations of claudin9 levels suffice to induce functional and mature inner hair cells

Chen, Y., Lee, J. H. H., Li, J., Park, S., Perez-Flores, M. C., Peguero, B., Kersigo, J., Kang, M., Choi, J., Levine, L., Gratton, M. A., Friztsch, B., Yamoah, E. N.

10.1101/2023.10.08.561387 — Posted: 2024-11-08

Epidermal loss of PRMT5 leads to the emergence of an atypical basal keratinocyte-like cell population and defective skin stratification

Recka, N. M., Simons, A., Cornell, R. A., Van Otterloo, E.

10.1101/2024.11.08.620904 — Posted: 2024-11-08

Estimated benefit of PCSK9 inhibition following ischemic stroke due to severe intracranial atherosclerosis

Siegler, J. E., Badillo Goicoechea, E., Yaghi, S., Morsi, R. Z., Arevalo, A., Smith, M. M., Kothari, S., Desai, H., Sehgal, N., Rana, R., Kellogg, C., Jhaveri, A., de Havenon, A., Dunne, T., Cameron, K., Chaturvedi, S., Ghannam, M., Prabhakaran, S., Coleman, E., Brorson, J. R., Mehendale, R., Kass-Hout, T.

10.1101/2024.10.31.24316532 — Posted: 2024-11-05

Structural basis of gap-filling DNA synthesis in the nucleosome by DNA Polymerase β

Weaver, T. M., Ryan, B. J., Thompson, S. H., Hussen, A. S., Spencer, J. J., Xu, Z., Schnicker, N. J., Freudenthal, B. D.

10.1101/2024.11.04.621902 — Posted: 2024-11-04

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