Channel:  Francis Crick Institute

1,190 Articles

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Inhibition of neutrophil degranulation by Nexinhib20 delays the development of radiation-induced pulmonary fibrosis
Ruhland, S., Nikolatou, K., Bridgeman, V. L., Rizou, T., Sahai, E., Bordoloi, J., Nolan, E., Elosegui-Artola, A., Malanchi, I.
10.1101/2025.10.22.684057 — Posted: 2025-10-23
Cancer-driven neutrophil priming couples systemic epithelial regenerative programs with pre-metastatic niche formation
Rabas, N., Bridgeman, V., Hennequart, M., Rodrigues, F. S., Farias, A., Ferreira, R. M. M., Axarlis, K., Nduka, O., Chakravarty, P., Legrave, N., Furlani, I., Malanchi, I.
10.1101/2025.10.20.683483 — Posted: 2025-10-21
Autoantibody origins in lupus and in relapse post CAR-T therapy
Grenov, A., Yoon, J., Snell, D. M., Mikolajczak, A., Wang, H., Gurel, E., Rodriguez-Ronchel, A., Yegen, G., Lee, L., Artim Esen, B., Rahman, A., Maciocia, P., Vinuesa, C.
10.1101/2025.10.20.683393 — Posted: 2025-10-20
Genome-wide Chromosome-specific Aneuploidy Engineering and Phenotypic Characterization with CRISPR-Taiji
Feng, H., Deng, D., Dahiya, R., Wang, L., Zeng, J., Tan, B. J. Y., Byrne, F., Shepherd, S. T. C., Wang, J., Johnson, S. C., Harrod, A., Lane, K. A., Fendler, A., Cattin, A.-L., Tippu, Z., Nie, M., Zhao, Y., Wang, R., Ai, W., Bouricha, O., Barber, T., Dovga, Y., Xu, Y., Shen, W., Sun, Z., Wang, H., Zhu, J., Xu, Y., Devito, L. G., Healy, L., Lim, E. S., OToole, S. M., Akker, S., Drake, W. M., Jin, H., Downs, J. A., McClelland, S. E., Diffley, J. F. C., Ly, P., Turajlic, S.
10.1101/2025.04.25.650684 — Posted: 2025-10-18
VGLL1 contributes to both the transcriptome and epigenome of the developing trophoblast compartment
Calderon, R. I., Sah, N., Huang, M., Kallol, S., Kittle, R. H., Shaik, W., Abdelaal, A., Chousal, J. N., Morey, R., Bui, T., Mitre, A., Fogarty, N. M. E., Gerri, C., Manalo, Z., Zheng, C., DeHoff, P. M., Home, P., Niakan, K., Cook-Andersen, H., Fisch, K. M., Paul, S., Soncin, F.
10.1101/2025.04.25.650693 — Posted: 2025-10-15
The SNCA A53T mutation sensitizes human neurons and microglia to ferroptosis
Mahoney-Sanchez, L., Clarke-Lucas, H., Penverne, A., Evans, J. R., D'Sa, K., Strohbuecker, S., Lopex Garcia, P., Cosker, K., Soltic, D., O'Callaghan, B. J., Griffiths, A., Pintchovski, S. A., Plun-Favreau, H., Hallqvist, J., Mills, K., Gandhi, S.
10.1101/2025.10.13.682089 — Posted: 2025-10-14
Ecological cues orchestrate concerted courtship in a Drosophila host specialist
Brand, P., Keller, K., Coleman, R. T., Eghbali, N. B., Zylka, S., Prieto-Godino, L. L., Ruta, V.
10.1101/2025.10.13.681913 — Posted: 2025-10-14
The origin and molecular evolution of the mammalian liver cell architecture
Yuan, X., Rodriguez-Montes, L., Zaremba, B., Trost, N., Schneider, C., Schmidt, J., Berki, B., Ibberson, D., Leushkin, E., Nickel, B., Palkovits, M., Truman, R. W., Barsh, G., Lees, J., Fallahshahroudi, A., Grützner, F., Tzika, A. C., Milinkovitch, M. C., Pääbo, S., Cardoso-Moreira, M., Kaessmann, H.
10.1101/2025.10.14.682049 — Posted: 2025-10-14
Extensive and differential platinum chemotherapy mutagenesis in children
Wenger, A., Lee-Six, H., Dave, M., Layeghifard, M., Lawson, A. R. J., Abascal, F., Nicola, P. A., Treger, T. D., Ogbonnah, T., Parks, C., Oliver, T. R. W., Kennedy, J., Hodder, A., Anderson, N. D., Silva, F. L. T., Trinh, M. K., Dowe, T., Habarwaa, M., Sun, J. J., Assia-Zamora, S., Cortes-Cerisuelo, M., Jassem, W., Town, C., Dhawan, A., Jain, V., Straathof, K., Deheragoda, M., Martincorena, I., Palm, L., Hutchinson, J. C., Coorens, T. H. H., Trayers, C., Heaton, N., Shlien, A., Zen, Y., Rouhani, F. J., Behjati, S.
10.1101/2025.10.12.681852 — Posted: 2025-10-14
Cell cycle oscillations in a polarity network facilitate state switching by morphogenetic cues
Ng, K., Sebaa, H., Hirani, N., Chizh, A., Messi, Z., Bland, T., Sugioka, K., Goehring, N. W.
10.1101/2025.10.12.681824 — Posted: 2025-10-13

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