Channel:  Francis Crick Institute

1,312 Articles

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RAS-PI3K signaling promotes myofibroblastic CAF identity and restrains an immunomodulatory stromal program
Cuesta, C., Alcon-Perez, M., Cota, R. R., Coadour, S., Zheng, J., Procel, N., Fennema, D., Rosell, A., Meson, D. L., Martinez-Castedo, B., Arafat, Y., Sanz-Fraile, H., Rajeeve, V., Alonso, D., Hynds, R. E., Swanton, C., Alcaraz, J., Cutillas, P., Reyes-Aldasoro, C. C., Wang, H., Castellano, E.
10.1101/2025.01.20.633776 — Posted: 2026-07-14
Gene Regulatory Networks Mediate Pattern Scaling in Growing Tissues
Bowen, A. E., Hadjivasiliou, Z.
10.64898/2026.07.08.737218 — Posted: 2026-07-12
Mitochondrial Optic Atrophy (OPA)1 expression regulates the injury response to neonatal hypoxia-ischaemia.
Curel, C., Jones, A., Crawford, A. H., Goikolea Vives, A., Chabrier, G., Gil, G., Oregioni, A., Southworth, R., Eykyn, T. R., Stolp, H. B., Nobeli, I., Thornton, C.
10.64898/2026.05.21.726935 — Posted: 2026-07-10
Dynamic interaction between tentacle-tethered microdomains in Integrator and NELF regulates the promoter-proximal pause checkpoint
Blears, D., Bech, P., Martinez, D. L., Dai, P., Shah, R. A., Fong, N., Han, Z., Mitter, R., Sheridan, R., Johansen, J. V., Dirac-Svejstrup, A. B., Bentley, D., Svejstrup, J. Q.
10.64898/2026.06.30.735463 — Posted: 2026-07-09
PKN2 regulates cell-junctions to limit colitis
Henry, J. C., Campbell, A., Huddar, P., Sewell, J., Menezes, S., Passman, A., Smith, K., McGauran, S., Quetier, I., Lin, M.-L., Jansen, M., McDonald, N., Graham, T. A., McDonald, S., Cameron, A. J.
10.64898/2025.12.15.694339 — Posted: 2026-07-09
Fitness and immune-escape within germinal centers shape premalignant evolution toward lymphoma
Zhang, L., Hung, M. S., Atkins, O., Artemov, P., Sochon, A., Boulat, V., Kashkar, H., Reinhardt, H. C., Fitzgibbon, J., Okosun, J., Calado, D. P.
10.64898/2026.06.25.734549 — Posted: 2026-07-09
Solid-like PAR protein assemblies encode long-term spatial memory of cell polarity during suspended animation
Borrego-Pinto, J., Cornwall Scoones, J., Hirani, N., Ng, K., Baum, B., Banerjee, S., Goehring, N. W.
10.64898/2026.06.30.733387 — Posted: 2026-07-09
Low-abundance αSyn-112 promotes αSyn-140 aggregation in vitro and forms immunoreactive deposits in Parkinson's disease brain tissue
Röntgen, A., Fusco, G., Breiter, J., Beckwith, J. S., Lachica, J., Toomey, C. E., Singh, J., Klementieva, O., Gandhi, S., Lee, S., De Simone, A., Toprakcioglu, Z., Vendruscolo, M.
10.64898/2026.07.05.736591 — Posted: 2026-07-09
Multi-Site Reproducibility Study of 3D High-Content Analysis with Dual-View Oblique Plane Microscopy
Alexandrov, Y., Arias-Garcia, M., Bakal, C., Batlle, E., Bousgouni, V., Carragher, N., Colombelli, J., Culley, J., Curry, N., Dent, L., Dunsby, C., Dvinskikh, L., Garcia, E., Giakoumakis, N. N., Gustafsson, N., Llanses, M., Lee, M., Mandke, K. N., Marks, D., McNeish, I., Ratcliffe, C., Sahai, E., Sparks, H., Suckert, T.
10.64898/2026.06.29.735376 — Posted: 2026-07-08
Relapse-founding cancer persister cells in follicular lymphoma
Atkins, O., Hung, M. S., Song, O.-R., Chen, B., Maybury, B., Edmondson, C., Tesson, B., Huet, S., Salles, G., Howell, M., Reinhardt, H. C., Fitzgibbon, J., Okosun, J., Zhang, L., Calado, D. P.
10.64898/2026.06.23.734001 — Posted: 2026-07-08

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