Channel:  The Howard Hughes Medical Institute (HHMI)

1,871 Articles

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An in planta single-cell screen to accelerate functional genetics
Lowensohn, T. N., Cody, W. B., Tsai, C., Vlahos, A. E., Call, C. C., Gao, X. J., Sattely, E. S.
10.1101/2025.08.06.668818 — Posted: 2026-01-09
Architecting cis-regulation to quantitatively tune gene expression in cereals
Groover, E. D., Ding, D., Wang, F. Z., Benegas, G., Rivera, J., Schwartz, S., Chen, S., Moubarak, M. F., Georgieva, V., Lemaux, P. G., Staskawicz, B., Niyogi, K. K., Song, Y. S., Savage, D.
10.64898/2026.01.08.698005 — Posted: 2026-01-08
Hidden Markov models detect recombination and ancestry of SARS-CoV-2
Masaki, N., Bedford, T.
10.1101/2025.11.08.687354 — Posted: 2026-01-08
Synthetic Control of Implanted Engineered Liver Tissue Growth
Stoddard, A. E., Kumar, V., Tzouanas, C. N., Hui, V., Li, J., Jain, A., Farrell, A., Bhatia, S., Chen, C. S.
10.64898/2025.12.10.693527 — Posted: 2026-01-07
Influenza hemagglutinin subtypes have different sequence constraints despite sharing extremely similar structures
Ahn, J. J., Yu, T. C., Dadonaite, B., Radford, C. E., Bloom, J. D.
10.64898/2026.01.05.697808 — Posted: 2026-01-06
A genetic screen in enteroendocrine cells reveals mechanisms that control protein sensing and GLP-1 release
Yu, S., Lee, Y., Boggess, S. C., Klein, N. R., Teyssier, N., Kampmann, M., Knight, Z. A.
10.64898/2025.11.30.691441 — Posted: 2026-01-06
SCREWx: A Screwless, Chronic, Recoverable, and Lightweight Neuropixels fixture for freely-moving rodents
Cheng, A., DeWeese, T., Zhou, Y., Sueoka, Y., Koukuntla, S., Green, M., Cullen, K., Knierim, J., Graves, A., Harris, T.
10.64898/2026.01.06.697790 — Posted: 2026-01-06
An orthogonal TRAP enables intersectional genetic access to activated neurons in the mouse brain
Chatziris, N., Jarvie, B. C., Liu, C., Knight, Z. A.
10.64898/2025.11.30.691330 — Posted: 2026-01-06
Cellular coding of ingestion in the caudal brainstem
Ly, T., Yi, X., Lee, G. R., Grove, J. C., Sibih, Y. E., Oh, Y. Y., Qiu, L., Sivakumar, N., Knight, Z. A.
10.64898/2025.11.30.691333 — Posted: 2026-01-06
The E3 ubiquitin ligase mechanism specifying target-directed microRNA degradation
Farnung, J., Slobodyanyuk, E., Wang, P. Y., Blodgett, L. W., Lin, D. H., von Gronau, S., Schulman, B. A., Bartel, D. P.
10.64898/2026.01.05.697729 — Posted: 2026-01-05

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