Channel:  Harvard Program in Therapeutic Sciences

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

114 Articles

Multimodal Spatial Profiling Reveals Immune Suppression and Microenvironment Remodeling in Fallopian Tube Precursors to High-Grade Serous Ovarian Carcinoma
Kader, T., Lin, J.-R., Hug, C., Coy, S., Chen, Y.-A., de Bruijn, I., Shih, N., Jung, E., Pelletier, R. J., Leon, M. L., Mingo, G., Omran, D. K., Lee, J. S., Yapp, C., Satravada, B. A., Kundra, R., Xu, Y., Chan, S., Tefft, J., Muhlich, J. L., Kim, S., Gysler, S. M., Agudo, J., Heath, J. R., Schultz, N., Drescher, C., Sorger, P. K., Drapkin, R., Santagata, S.
10.1101/2024.09.25.615007 — Posted: 2024-09-27
Integrating spatial profiles and cancer genomics to identify immune-infiltrated mismatch repair proficient colorectal cancers
Wala, J., de Bruijn, I., Coy, S., Gagne, A., Chan, S., Chen, Y.-A., Hoffer, J., Muhlich, J., Schultz, N., Santagata, S., Sorger, P.
10.1101/2024.09.24.614701 — Posted: 2024-09-26
PRAME expression in melanoma is negatively regulated by TET2-mediated DNA hydroxymethylation
Fang, R., Vallius, T., Zhang, A., Van Cura, D., Alicandri, F., Fischer, G., Draper, E., Xu, S., Pelletier, R., Katsyv, I., Sorger, P. K., Murphy, G. F., Lian, C. G.
10.1101/2024.07.26.605293 — Posted: 2024-07-26
Sharing Data from the Human Tumor Atlas Network through Standards, Infrastructure, and Community Engagement
de Bruijn, I., Nikolov, M., Lau, C., Clayton, A., Gibbs, D. L., Mitraka, E., Pozhideyeva, D., Lash, A., Sumer, S. O., Altreuter, J., Anton, K., DeFelice, M., Li, X., Lisman, A., Longabaugh, W. J. R., Muhlich, J., Sandro, S., Nandakumar, S., Peter, S. K., Suver, C., Schultz, N., Taylor, A. J., Thorsson, V., Cerami, E., Eddy, J. A.
10.1101/2024.06.25.598921 — Posted: 2024-06-30
psudo: Exploring Multi-Channel Biomedical Image Data with Spatially and Perceptually Optimized Pseudocoloring
Warchol, S., Troidl, J., Muhlich, J. L., Krueger, R., Hoffer, J., Lin, T., Beyer, J., Glassman, E., Sorger, P. K., Pfister, H.
10.1101/2024.04.11.589087 — Posted: 2024-06-15
TYK2 as a novel therapeutic target in Alzheimer Disease
Konig, L., Rodriguez, S., Hug, C., Daneshvari, S., Chung, A., Bradshaw, G., Sahin, A., Zhou, G., Eisert, R., Piccioni, F., Das, S., Kalocsay, M., Sokolov, A., Sorger, P., Root, D., Albers, M. W.
10.1101/2024.06.04.595773 — Posted: 2024-06-06
Persistent Neurological Deficits in Mouse PASC Reveal Antiviral Drug Limitations
Verma, A. K., Lowery, S., Lin, L.-C., Duraisami, E., Abrahante, J. E. K., Qiu, Q., Hefti, M. M., Yu, R. C., Albers, M. W., Perlman, S.
10.1101/2024.06.02.596989 — Posted: 2024-06-03
Spatial Profiling of Metals through Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging
Stopka, S., Bodineau, C., Baquer, G., Lin, J.-R., Hossain, M. A., Regan, M. S., Ruiz, D. F., Fletcher, S.-M., Pourquie, O., Lutsenko, S., Payne, C., Agar, J. N., Mazitschek, R., McDannold, N., Sorger, P. K., Santagata, S., Agar, N.
10.1101/2024.05.22.594980 — Posted: 2024-05-23
Efficient and Robust Search of Microbial Genomes via Phylogenetic Compression
Brinda, K., Lima, L., Pignotti, S., Quinones-Olvera, N., Salikhov, K., Chikhi, R., Kucherov, G., Iqbal, Z., Baym, M.
10.1101/2023.04.15.536996 — Posted: 2024-05-11
A general algorithm for consensus 3D cell segmentation from 2D segmented stacks
Zhou, F. Y., Yapp, C., Shang, Z., Daetwyler, S., Marin, Z., Islam, M. T., Nanes, B. A., Jenkins, E., Gihana, G. M., Chang, B.-J., Weems, A., Dustin, M., Morrison, S. J., Fiolka, R. P., Dean, K. M., Jamieson, A., Sorger, P. K., Danuser, G.
10.1101/2024.05.03.592249 — Posted: 2024-05-06

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