Channel:  Harvard Program in Therapeutic Sciences

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

89 Articles

Parallel evolution of mutational fitness effects over 50,000 generations
Limdi, A., Owen, S. V., Herren, C., Lenski, R. E., Baym, M.
10.1101/2022.05.17.492023 — Posted: 2023-03-07
Multi-modal digital pathology for colorectal cancer diagnosis by high-plex immunofluorescence imaging and traditional histology of the same tissue section
Lin, J.-R., Chen, Y.-A., Campton, D., Cooper, J., Coy, S., Yapp, C., Tefft, J., McCarty, E., Ligon, K., Rodig, S. J., Reese, S., George, T., Santagata, S., Sorger, P. K.
10.1101/2022.09.28.509927 — Posted: 2023-02-21
A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments
Chidley, C., Darnell, A. M., Gaudio, B. L., Lien, E. C., Barbeau, A. M., Vander Heiden, M. G., Sorger, P. K.
10.1101/2023.01.26.525375 — Posted: 2023-01-26
3D multiplexed tissue imaging reconstruction and optimized region-of-interest (ROI) selection through deep learning model of channels embedding
Burlingame, E., Ternes, L., Lin, J.-R., Chen, Y.-A., Kim, E. N., Gray, J. W., Santagata, S., Sorger, P. K., Chang, Y. H.
10.1101/2022.12.09.519807 — Posted: 2022-12-12
A Web-based Software Resource for Interactive Analysis of Multiplex Tissue Imaging Datasets
Creason, A. L., Watson, C., Gu, Q., Persson, D., Sargent, L. L., Chen, Y.-A., Lin, J.-R., Sivagnanam, S., Wünnemann, F., Nirmal, A. J., Chin, K., Feiler, H. S., Coussens, L. M., Schapiro, D., Grüning, B. A., Sorger, P. K., Sokolov, A., Goecks, J.
10.1101/2022.08.18.504436 — Posted: 2022-12-03
Prediction and Curation of Missing Biomedical Identifier Mappings with Biomappings
Hoyt, C. T., Hoyt, A. L., Gyori, B. M.
10.1101/2022.11.29.518386 — Posted: 2022-12-02
OpenFold: Retraining AlphaFold2 yields new insights into its learning mechanisms and capacity for generalization
Ahdritz, G., Bouatta, N., Kadyan, S., Xia, Q., Gerecke, W., O'Donnell, T. J., Berenberg, D., Fisk, I., Zanichelli, N., Zhang, B., Nowaczynski, A., Wang, B., Stepniewska-Dziubinska, M. M., Zhang, S., Ojewole, A., Guney, M. E., Biderman, S., Watkins, A. M., Ra, S., Lorenzo, P. R., Nivon, L., Weitzner, B., Ban, Y.-E. A., Sorger, P. K., Mostaque, E., Zhang, Z., Bonneau, R., AlQuraishi, M.
10.1101/2022.11.20.517210 — Posted: 2022-11-24
Assembling a corpus of phosphoproteomic annotations using ProtMapper to normalize site information from databases and text mining
Bachman, J. A., Sorger, P. K., Gyori, B. M.
10.1101/822668 — Posted: 2022-10-29
NDEx IQuery: a multi-method network gene set analysis leveraging the Network Data Exchange
Pillich, R. T., Chen, J., Churas, C., Fong, D., Gyori, B. M., Ideker, T., Karis, K., Liu, S. N., Ono, K., Pico, A., Pratt, D.
10.1101/2022.10.24.513552 — Posted: 2022-10-25
Unifying the Identification of Biomedical Entities with the Bioregistry
Hoyt, C. T., Balk, M., Callahan, T. J., Domingo-Fernandez, D., Haendel, M. A., Hegde, H. B., Himmelstein, D. S., Karis, K., Kunze, J., Lubiana, T., Matentzoglu, N., McMurry, J., Moxon, S., Mungall, C. J., Rutz, A., Unni, D. R., Willighagen, E., Winston, D., Gyori, B. M.
10.1101/2022.07.08.499378 — Posted: 2022-10-22

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