Channel:  The Howard Hughes Medical Institute (HHMI)

1,975 Articles

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New methods for epigenetic characterization and manipulation of rare fly brain neurons
Ojha, P., Berglund, G., Yu, A. D., Rosbash, M.
10.64898/2026.01.21.700891 — Posted: 2026-01-23
Inference of germinal center evolutionary dynamics via simulation-based deep learning
Ralph, D. K., Bakis, A. G., Galloway, J., Vora, A. A., Araki, T., Song, Y. S., DeWitt, W. S., Matsen, F. A.
10.1101/2025.08.12.669950 — Posted: 2026-01-22
Sciphy: A Bayesian phylogenetic framework using sequential genetic lineage tracing data.
Seidel, S., Zwaans, A., Regalado, S., Choi, J., Shendure, J., Stadler, T.
10.1101/2024.10.01.615771 — Posted: 2026-01-22
Strong sustained type I IFN signaling acts cell intrinsically to impair IFNγ responses and cause tuberculosis susceptibility
Fattinger, S. A., Chavez, R. A., Witt, K. C., Parisi, B., Rodriguez, J. J., Turcotte, E. A., Brydon, E. C., Fairgrieve, M. R., Dhaliwal, H., Lee, A. Y., Kotov, D. I., Vance, R. E.
10.64898/2026.01.19.700487 — Posted: 2026-01-22
High-efficiency targeted integration of extrachromosomal arrays in C. elegans using PhiC31 integrase
Rich, M. S., Pellow, R., Hefel, A., Rog, O., Jorgensen, E. M.
10.1101/2025.11.11.687718 — Posted: 2026-01-21
Inefficient autophagosome formation limits the temporal dynamics of OPTN-mediated mitophagy in neurons
Green, J. R., Gooden, M. K., Ojo, A. E., Kalejaiye, T. D., Evans, C. S.
10.64898/2026.01.16.700014 — Posted: 2026-01-20
Establishing the molecular basis for MDA5 mutation-linked autoimmunity
Xu, L., Chung, K., Guo, R., Pan, A., Pyle, A.
10.64898/2026.01.20.700587 — Posted: 2026-01-20
UnionLoops: a workflow for calling chromatin loops across related Hi-C datasets with improved specificity, precision, and sensitivity
Liu, J., Gibcus, J. H., Dekker, J.
10.64898/2026.01.19.700311 — Posted: 2026-01-20
PfApiAT2 is a proline transporter essential for the transmission of Plasmodium falciparum by the mosquito vector.
Khushu, M., Kissel, R. C., Kauffman, J., Taccheri, C., Singh, N., Summers, R. L., Plant, L. D., Wirth, D., Catteruccia, F., Bopp, S.
10.64898/2026.01.20.700404 — Posted: 2026-01-20
Structural and Spectroscopic Basis for Catalysis by a Class C Radical S-adenosylmethionine Methylase Involved in Nosiheptide/Nocathiacin Biosynthesis
Wang, B., Knox, H. L., York, N. J., Radle, M. I., Silakov, A., Booker, S. J.
10.64898/2026.01.19.700444 — Posted: 2026-01-20

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