Channel:  The Howard Hughes Medical Institute (HHMI)

2,523 Articles

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FlyPredictome: A structural atlas of predicted protein-protein interactions in Drosophila
Kim, A.-R., Comjean, A., Veal, A., Rodiger, J., Han, M., Hu, Y., Perrimon, N.
10.64898/2026.04.14.718529 — Posted: 2026-08-18
Temporal single-cell profiling of the parabrachial Calca neurons reveals molecular dynamics driving nociplastic pain
Park, S., Clarke, H. H., Cao, F., Rose, A. D., Yang, E., Felix, R. R., Read, J., Chen, J. Y., Pauli, J. L., Palmiter, R. D.
10.64898/2026.08.07.743567 — Posted: 2026-08-17
Protein design to broadly reprogram engineered T cell function
Boyken, S. E., Merillat, S., Langan, R. A., Moffett, H. F., Coventry, B., Haeseleer, F., Haworth, K. G., Goreshnik, I., DeSautelle, J., Chukinas, J., Hammerson, B., Davenport, T. M., Nguyen, D., Amin, R., Yuan, S., Foight, G. W., Weitzner, B. D., Foster, A. E., Baker, D., Lajoie, M. J.
10.64898/2026.08.13.742806 — Posted: 2026-08-17
Humans homozygous for rare or common hypomorphic IL23R variants are prone to tuberculosis
Olguin Calderon, D., Kilpatrick, L. E., Conil, C., Philippot, Q., Ogishi, M., Vellutini, J., Eun Han, J., Keating, N., Li, H., Rao, G., Bohlen, J., Lay, C. S., Platt, S., Kerner, G., Feredj, E., Peel, J., Momenilandi, M., Seeleuthner, Y., Laine, C., soudee, c., Leloup, C., Debuisson, C., Lanternier, F., Bitoun, S. B., Pavy, S., Mariette, X., Rafik, A., Skhoun, H., EL Ouazzani, H., Abderahmani-Ghorfi, I., EL Baghdadi, J., Baena, A., Tejada-Giraldo, M., Barrera, L. F., Arias, A. A., Fabio, G., Carrabba, M., Emiroglu, M., Bezrodnik, L., EL Zein, L., Hammoud, H., Gregersen, P., Terrier, B., Leon L
10.64898/2026.03.23.713554 — Posted: 2026-08-13
Photometallobiocatalytic Asymmetric Radical-Mediated Cross-Coupling of Organotrifluoroborate Salts and Pyridotriazoles
Wang, H., Mai, B. K., Zhang, X., Li, C., Liu, P., Yang, Y.
10.64898/2026.08.11.744224 — Posted: 2026-08-12
The mycomembrane proteins PorH and ProtX are inserted at polar growth zones and linked to the cell wall
Hart, E. M., de Bruin, D. A., Marando, V. M., Alemany, M. A., Snow, E. D., Schultz, B. J., Kuru, E., Walker, S., Vettiger, A., Bernhardt, T. G.
10.1101/2025.10.14.682376 — Posted: 2026-08-12
Reprogramming Cas9 PAM Recognition for Allele-Specific Editing
Tartaglia, J. A., Nguyen, V., Desmarais, J., Weissman, R., Thornton, B., Trinidad, M., Briseno, K., Hudson, T., Catamura, C., Lareau, L., Urnov, F., Doudna, J. A., Savage, D.
10.64898/2026.08.10.744034 — Posted: 2026-08-11
A multi-species toolkit of TOP2 hypercleavage mutants for studying topoisomerase II-mediated DNA damage
Ontoso, D., Mehta, M., Shabro, A., Dittmar, J., Reid, R. J. D., Rothstein, R., Nitiss, J. L., Keeney, S.
10.64898/2026.05.09.723998 — Posted: 2026-08-11
Alternative splicing of synaptotagmin 7 regulates oligomerization and short-term synaptic plasticity
Mehta, N., Larson, D. T., Wozney, M., Mishra, S., Subramani, S., Kaur, S., Jain, A., Chapman, E. R.
10.1101/2025.10.27.684894 — Posted: 2026-08-11
RADIX: a deep learning framework that maps root barriers across species and reveals genetic and environmental contributions
Gu, Y., Sanow, S., Taylor, T., Morimoto, K. W., Nemer, A., Hadley, D. J., Zafar, S. A., DeMello, L., Chen, Y., Knab, H., Busch Castro, A., Kumaravelu, V., Bailey-Serres, J., Carney, R., Brady, S.
10.64898/2026.08.07.743584 — Posted: 2026-08-10

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