Channel: University of Chicago

This collection includes bioRxiv and medRxiv papers from authors at University of Chicago.

2409 Articles

ALPK3 heterozygous truncating variants cause late-onset hypertrophic cardiomyopathy with frequent apical involvement and apical aneurysm

Busse, L. H., Huth, E. A., Abraham, M. R., Abraham, T., Padmanabhan, A., Wojciak, J., Wright, G., Aatre, R., Campagna, R., Jackson, E., Kreykes, S. E., Lane, K., Sawyer, L., Stevens, C., Thomas, M. J., VanDyke, R. E., Vedantham, V., Higgs, E.

10.1101/2024.11.14.24317359 — Posted: 2024-11-15

Pre-frontal cortical activity during gait is altered in pre-manifest and early spinocerebellar ataxia

Mancini, M., Silva-Batista, C., Shah, V. V., Horak, F. B., Carlson-Kuhta, P., Safarpour, D., Gomez, C. M.

10.1101/2024.11.14.24317186 — Posted: 2024-11-15

MIRAGE: a Bayesian rare variant association analysis method incorporating functional information of variants

Han, S., Sun, X., Sloofman, L., Satterstrom, F. K., Wang, G., Liang, L., Knoblauch, N., Zhao, S., Liu, Y., Sheng, W., Nguyen, H. T., He, X.

10.1101/828061 — Posted: 2024-11-15

Pervasive polygenicity of complex traits inflates false positive rates in transcriptome-wide association studies

Liang, Y., Nyasimi, F., Im, H. K.

10.1101/2023.10.17.562831 — Posted: 2024-11-15

scPrediXcan integrates advances in deep learning and single-cell data into a powerful cell-type-specific transcriptome-wide association study framework

Zhou, Y., Adeluwa, T., Zhu, L., Salazar, S., Sumner, S., Kim, H., Gona, S., Nyasimi, F., Kulkarni, R., Powell, J., Madduri, R., Liu, B., Chen, M., Im, H. K.

10.1101/2024.11.11.623049 — Posted: 2024-11-14

Inflammation-Induced Claudin-2 Upregulation Limits Pancreatitis Progression by Enhancing Tight Junction-Controlled Pancreatic Ductal Transport

Kesaraju, S., Li, Y., Xing, J., Tracy, M., Wannemo, K., Holder, A., Zhao, P., Khan, M. A., Kainov, J., Rana, N., Sidahmed, M., Hyoju, S., Smith, L., Matthews, J., Tay, S., Khalili-Araghi, F., Rana, M., Oakes, S., Shen, L., Weber, C.

10.1101/2023.09.01.555960 — Posted: 2024-11-13

Semaphorin 4A maintains functional diversity of the hematopoietic stem cell pool

Toghani, D., Gupte, S., Zeng, S., Mahammadov, E., Crosse, E., Seyedhassantehrani, N., Burns, C., Gravano, D., Radtke, S., Kiem, H.-P., Rodriguez, S., Carlesso, N., Pradeep, A., Georgiades, A., Lucas, F., Wilson, N. K., Kinston, S. J., Gottgens, B., Zong, L., Beerman, I., Park, B., Janssens, D., Jones, D., Toghani, A., Nerlov, C., Pietras, E. C., Mesnieres, M., Maes, C., Kumanogoh, A., Worzfeld, T., Cheong, J.-G., Josefowicz, S. Z., Kharchenko, P., Scadden, D., Scialdone, A., Spencer, J. A., Silberstein, L.

10.1101/2024.11.12.622506 — Posted: 2024-11-13

Illuminating microbial mat assembly: Cyanobacteria and Chloroflexota cooperate to structure light-responsive biofilms

Bunbury, F., Rivas, C., Calatrava, V., Malkovskiy, A., Joubert, L.-M., Parvate, A., Evans, J. E., Grossman, A. R., Bhaya, D.

10.1101/2024.07.24.605005 — Posted: 2024-11-12

The Impact of Charge Regulation and Ionic Intranuclear Environment on the Nucleosome Core Particle

Nap, R. J., Gonzalez, P. C., Coraor, A. E., Virk, R. K. A., de Pablo, J. J., Backman, V., Szleifer, I.

10.1101/2024.11.11.623012 — Posted: 2024-11-12

ROSIE: AI generation of multiplex immunofluorescence staining from histopathology images

Wu, E., Bieniosek, M., Wu, Z., Thakkar, N., Charville, G. W., Makky, A., Schürch, C., Huyghe, J. R., Peters, U., Li, C. I., Li, L., Giba, H., Behera, V., Raman, A., Trevino, A. E., Mayer, A. T., Zou, J.

10.1101/2024.11.10.622859 — Posted: 2024-11-11

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