Channel:  Aligning Science Across Parkinson's (ASAP)

542 Articles

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Repetitive Levodopa Treatment Drives Cell Type-Specific Striatal Adaptations Associated With Progressive Dyskinesia in Parkinsonian Mice
Paz, R. M., Ryan, M. B., Marcott, P. F., Girasole, A. E., Faryean, J., Duong, V., Sridhar, S., Nelson, A. B.
10.1101/2025.05.16.654598 — Posted: 2026-10-29
Comparative molecular mapping reveals molecular gradients and spatially organized populations in the subthalamic and para-subthalamic regions
Dumas, S., Francois, C., Biviano Rosenkilde, M., Staryk, J., Roostalu, U., Heuer, A., Karachi, C., Wallen-Mackenzie, A.
10.1101/2025.05.21.655268 — Posted: 2026-10-28
Strategies to establish a biologically defined Parkinson's disease cohort prior to the onset of clinically significant motor symptoms
Brown, E. G., Blumenau, H., Lafontant, D.-E., Nair, A. R., Johnson, N., Alcalay, R. N., Chahine, L. M., Coffey, C. S., Dobkin, R. D., Foroud, T., Galasko, D., Merchant, K., Mollenhauer, B., Poston, K. L., Siderowf, A., Tanner, C. M., Weintraub, D., Marek, K., Simuni, T., Tropea, T. F., Parkinson's Precision Medicine Initiative
10.64898/2026.10.26.26366535 — Posted: 2026-10-28
Genetic Modifiers of Age at Onset for Parkinson's Disease in European Populations
The Global Parkinson's Genetics Program (GP2), , Voss, E.
10.64898/2026.10.20.26363947 — Posted: 2026-10-26
Coordinated spatial organization of basal ganglia structures revealed by dopamine subtype projectome mapping
Moreno-Ramos, O. A., Raj, D. D. A., Vigotsky, A. D., Schonfeld, E., Phelan, E., Singh, A., Jenkins, J. C., Gaertner, Z., Bolduc, C., Oram, C., Kim, L., Luppi, M. P., Nissan, M. S., Onay, T., Markoulaki, S., Lerner, T. N., Surmeier, D. J., Apkarian, A. V., Poulin, J.-F., Dombeck, D., Awatramani, R.
10.64898/2026.10.21.760539 — Posted: 2026-10-24
Alpha-synuclein and neuromelanin converge to promote Parkinsons disease pathology
Nicolau-Vera, A., Gonzalez-Sepulveda, M., Cladera-Sastre, J. M., Cuadros, T., Parent, A., Roch, G., Marongiu, J., Huynh, B., Mahabadian, A. A., Su, F., Chatterton, Z., Hoyo, J., Laguna, A., Fu, Y., Halliday, G., Vila, M.
10.64898/2026.10.19.760151 — Posted: 2026-10-24
Structure and function of the DFCP1 membrane barrier responsible for ER microdomain organization in lysosome repair
Cui, Z., Palacio-Rodriguez, K., Herrmann, E., Kourniotis, A., Radulovic, M., Pust, S., Tapia, K., Raiborg, C., Hummer, G., Stenmark, H., Hurley, J. H.
10.64898/2026.10.19.759623 — Posted: 2026-10-23
Network analysis of α-synuclein pathology progression reveals p21-activated kinases as regulators of vulnerability
Vatsa, N., Brynildsen, J. K., Goralski, T. M., Kurgat, K., Meyerdirk, L., Breton, L., DeWeerd, D., Brasseur, L., Turner, L., Becker, K., Gallik, K. L., Isaguirre, C., Sheldon, R. D., Bassett, D. S., Henderson, M. X.
10.1101/2024.10.22.619411 — Posted: 2026-10-21
Q-DOAS: A Proximity Quenching Assay for Real-Time Detection of Early Protein Aggregation Events
Kleczko, K. M., Gestaut, D., Dobbins, S., Abramovich, J., Sitron, C. S., Li, L., Chan, R., Wang, N., Yang, X. W., Hartl, F.-U., Frydman, J.
10.64898/2026.06.16.732424 — Posted: 2026-10-21
PD-RISK Index: Piloting an unsupervised toolkit to identify adults with Parkinson disease
Li, J., Grimes, K., Saade, J., Lewis, D., Tomlinson, J. J., Frank, A., Ramsay, T., Salmaso, N., Manuel, D., Schlossmacher, M. G.
10.64898/2026.04.30.26352172 — Posted: 2026-10-19

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