Channel:  Aligning Science Across Parkinson's (ASAP)

524 Articles

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Reconstitution of multistep recruitment of ULK1 to membranes in autophagy
Duan, Y., Lu, Y., Paul, S., Betz, J., Wilhelm, L. P., Cook, A. S. I., Ren, X., Adriaenssens, E., Martens, S., Ganley, I., Hummer, G., Hurley, J. H.
10.1101/2025.11.07.687251 — Posted: 2026-08-12
Structural basis for the selective inhibition of the PI3KC3-C2 complex by Rubicon in endolysosome maturation and mitophagy
Chen, M., Bishnu, A., Duan, Y., Riley, J. F., Ni, Q., Joiner, A., Allen, I. J., Holzbaur, E., Ganley, I., Hurley, J. H.
10.64898/2026.08.07.743589 — Posted: 2026-08-10
A guanosine nucleotide metabolism-bioenergetics intersection drives Parkinson's disease
Kokotos, A. C., Unda, S. R., Reyes-Perez, P. R., Isayan, M., Perinan, M. T., Kaplitt, M. G., Ryan, T. A.
10.64898/2026.07.29.741503 — Posted: 2026-08-10
Age-dependent brain pigmentation drives early neuroinflammatory molecular signatures linked to neurodegeneration
Penuelas, N., Xicoy, H., Lorente-Picon, M., Nicolau-Vera, A., Parent, A., Gonzalez-Sepulveda, M., Laguna, A., Vila, M.
10.64898/2026.08.03.742448 — Posted: 2026-08-07
Cholesterol Dysregulation in APOE4 Astrocytes Promotes α-Synuclein Pathology in miBrains, a Human Brain Tissue Model
Mesentier-Louro, L. A., Goldman, C., Gaese, S., Buonfiglioli, A., Kyriakis, D., Harlock, A., Ndayisaba, A., Sartori, E. R., Uchitelev, A., Fullard, J. F., Hennigan, E., Lee, D., Schuldt, B. R., Rooklin, R. B., Barra, J., Bravo-Cordero, J. J., Roussos, P., Khurana, V., Blanchard, J. W.
10.1101/2025.02.09.637107 — Posted: 2026-08-04
A lipid transfer-dependent feedback loop activates ATG9A compartments in autophagy initiation
Holzer, E., Sawa-Makarska, J., Bernklau, D., Romanov, J., Schuschnig, M., Martens, S.
10.1101/2025.08.16.670665 — Posted: 2026-08-04
Health phenome of Parkinson's patients reveals prominent mood-sleep cluster
Olsen, A. L., Locascio, J. J., Tuncali, I., Laroussi, N., Abatzis, E., Kamenskaya, P., Kuras, Y., Yi, T., Videnovic, A., Hayes, M. T., Ho, G. P. H., Paulson, J., Khurana, V., Herrington, T. M., Hyman, B. T., Selkoe, D. J., Growdon, J. H., Gomperts, S. N., Riise, T., Schwarzschild, M. A., Hung, A. Y., Wills, A.-M., Scherzer, C. R.
10.1101/2022.02.01.22270276 — Posted: 2026-08-03
Time Course and Microcircuit Mechanisms of Primary Motor Cortex Dysfunction in Progressive Parkinsonism
Chen, L., Chehade, H. D., Somavarapu, S., Chu, H.-Y.
10.64898/2026.07.27.741031 — Posted: 2026-07-30
Structural Mechanisms of DNAJC13 Dimeric Assembly and InsP6 binding in Recycling Endosome Regulation
Fu, T., Lee, C., Hundley, F. V., Paulo, J. A., Harper, J. W.
10.64898/2026.07.28.740790 — Posted: 2026-07-29
Cerebrospinal fluid profile, including α-Synuclein seeding activity, of p.A53T SNCA mutation carriers: Data from the PPMI Study.
Simitsi, A. M., Papagiannakis, N., Alefanti, I., Piccilo, M., Barone, P., Lafontant, D.-E., Marek, K., Siderowf, A., Simuni, T., Koros, C., Stefanis, L.
10.64898/2026.07.23.26356817 — Posted: 2026-07-27

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