Channel:  Aligning Science Across Parkinson's (ASAP)

533 Articles

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Familial Parkinson's Disease Mutations Converge on Alternative Splicing Programs Linked to Lysosomal, Autophagic and Vesicle Trafficking Pathways
Lee, Y. J., Syed, K., Busquets, O., Li, H., Dunnack, J., Bateup, H., Soldner, F., Hockemeyer, D., Rio, D.
10.1101/2024.02.28.582420 — Posted: 2026-10-01
Stage-Specific NF-κB RelA and IRF4 Programs Drive -Synuclein-Induced Disease-Associated Microglia Differentiation
Yang, Y.-T., Greatti, Y., Miller, A. T., Webster, J. M., Jurkuvenaite, A., Randolph, J., Al-Dalahmah, O., Figge, D. A., Harms, A. S.
10.64898/2026.09.25.754514 — Posted: 2026-09-30
Repeated exposure to viral and bacterial danger signals in Parkin deficient mice induces inflammation but fails to trigger parkinsonism
Even, A., Mukherjee, S., Giguere, N., Brouillard-Galipeau, M., Oliveira, N. L., Halder, P., Beaulieu, C., Cayrol, R., Van Den Berge, N., Gruenheid, S., Trudeau, L.-E.
10.64898/2026.09.22.753365 — Posted: 2026-09-28
Genomic Landscape of Early-Onset and Familial Latin American Parkinson's Patients
Waldo, E., Chaparro-Solano, H. M., Isayan, M., Leal, T. P., Duarte-Zambrano, F., Inca-Martinez, M., Ramchandra, J., Rivera Paz, M., Makarious, M., Hernandez, C. F., Gatto, E. M., Gonzalez Rojas, N., Cesarini, M., Santos-Lobato, B. L., Letro, G. H., Orozco, J. L., Munoz Ospina, B., Chana-Cuevas, P., Rojas, N. A., Aguillon, D., Muller, V., Braga-Neto, P., Rodriguez-Violante, M., Cervantes-Arriaga, A., Schuh, A., Cornejo-Olivas, M., Mejia Rojas, K., Armas, C., Vinuela, A., Espinal Martinez, A. O., Tumas, V., Borges, V., Avila, C. L., Olguin, P., Alcauter, S., Kauffman, M., Gonzalez-Moron, D., Pen
10.64898/2026.09.16.26359514 — Posted: 2026-09-22
The impact of alpha synuclein overexpression on nigrostriatal transmission
Bergum, N., Yee, A., Edwards, R., Ford, C. P.
10.64898/2026.09.15.751842 — Posted: 2026-09-21
Elevated phosphorylated α-synuclein and phosphorylated tau in Lrrk2 p.G2019S-mutant mice following influenza A pneumonitis
Lunn, M. O., Thakur, K., Lengacher, N. A., Hake-Volling, Q., aSCENT-PD Investigators, , Tomlinson, J. J., Sad, S., Brown, E. G., Schlossmacher, M. G.
10.1101/2025.07.31.667659 — Posted: 2026-09-19
Sex-stratified analysis of the potential association between PGLYRP2 rs892145 variant and Parkinson's disease across diverse ancestral populations
Avila, C. L., Chaparro Solano, H. M., Quintana-Pena, V., Aberg, K., the Global Parkinson's Genetics Program (GP2), , Atterling Brolin, K.
10.1101/2025.07.23.25331993 — Posted: 2026-09-15
Impulse Control Disorders Are Independent of Parkinson Disease Motor Subtypes
Chhotani, M. E., Saban, W., Rossi, M., Kuo, S.-H., Montaser-Kouhsari, L., Lin, C.-Y. R., Parkinsons Precision Medicine Initiative
10.64898/2026.09.04.26362266 — Posted: 2026-09-08
Network analysis of α-synuclein pathology progression reveals p21-activated kinases as regulators of vulnerability
Vatsa, N., Brynildsen, J. K., Goralski, T. M., Kurgat, K., Meyerdirk, L., Breton, L., DeWeerd, D., Brasseur, L., Turner, L., Becker, K., Gallik, K. L., Isaguirre, C., Sheldon, R. D., Bassett, D. S., Henderson, M. X.
10.1101/2024.10.22.619411 — Posted: 2026-09-04
Dermal Phospho-Alpha-Synuclein Among Individuals With and Without Cerebrospinal Fluid Aggregated Alpha-Synuclein
Chahine, L., Chatterjee, K., Gochanour, C., Lafontant, D.-E., Akhtar, R., Shetty, N., Dahodwala, N., Brooker, S., Gonzalez-Latapi, P., Prakash, N., Defendorf, S., Midyette, J., Foroud, T., Merchant, K., Coughlin, D., Tropea, T. F., Frasier, M., Larson, D., Coffey, C., Marek, K., Simuni, T.
10.64898/2025.12.17.25342090 — Posted: 2026-09-02

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