Channel:  Aligning Science Across Parkinson's (ASAP)

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

239 Articles

Open-Source Platform for Kinematic Analysis of Mouse Forelimb Movement
Berezhnoi, D., Chehade, H. D., Chu, H.-Y.
10.1101/2024.01.31.578239 — Posted: 2024-04-15
A pathogenic variant in RAB32 causes autosomal dominant Parkinsons disease and activates LRRK2 kinase
Gustavsson, E. K., Follett, J., Trinh, J., Barodia, S. K., Real, R., Liu, Z., Grant-Peters, M., Fox, J. D., Appel-Cresswell, S., Stoessl, J. A., Rajput, A., Rajput, A. H., Auer, R., Tilney, R., Sturm, M., Haack, T. B., Lesage, S., Tesson, C., Brice, A., Vilarino-Gueell, C., Ryten, M., Goldberg, M. S., West, A. B., Hu, M. T., Morris, H. R., Sharma, M., Gan-Or, Z., Samanci, B., Lis, P., Tocino, T., Amouri, R., Ben Sassi, S., Hentati, F., Tonelli, F., Alessi, D. R., Farrer, M. J.
10.1101/2024.01.17.24300927 — Posted: 2024-01-18
Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies
Nazeen, S., Wang, X., Zielinski, D., Lam, I., Hallacli, E., Xu, P., Ethier, E., Strom, R., Zanella, C. A., Nithianandam, V., Ritter, D., Henderson, A., Saurat, N., Afroz, J., Nutter-Upham, A., Benyamini, H., Copty, J., Ravishankar, S., Morrow, A., Mitchel, J., Neavin, D., Gupta, R., Farbehi, N., Grundman, J., Myers, R. H., Scherzer, C. R., Trojanowski, J. Q., Van Deerlin, V. M., Cooper, A. A., Lee, E. B., Erlich, Y., Lindquist, S., Peng, J., Geschwind, D. H., Powell, J., Studer, L., Feany, M. B., Sunyaev, S. R., Khurana, V.
10.1101/2024.03.03.583145 — Posted: 2024-03-07
Targeted micro-fiber arrays for measuring and manipulating localized multi-scale neural dynamics over large, deep brain volumes during behavior
Vu, M.-A. T., Brown, E. H., Wen, M. J., Noggle, C. A., Zhang, Z., Monk, K. J., Bouabid, S., Mroz, L., Graham, B. M., Zhuo, Y., Li, Y., Otchy, T. M., Tian, L., Davison, I. G., Boas, D. A., Howe, M. W.
10.1101/2023.11.17.567425 — Posted: 2023-11-17
GLP-1 receptor agonism ameliorates Parkinsons disease through modulation of neuronal insulin signalling and glial suppression
Athauda, D., Evans, J. R., Sanchez, L., Virdi, G., Lopez Garcia, P., Wernick, A., Wagen, A., D'Sa, K., Lachica, J., Strohbuecker, S., Vecchi, G., Leighton, C., Saleeb, R. S., OShaughnessy, J., Toomey, C., Vijiaratnam, N., Girges, C., Li, Y., Mustapic, M., Ismail, K., Davies, M., Kapogiannis, D., Choi, M. L., Ryten, M., Horrocks, M. H., Greig, N. H., Foltynie, T., Gandhi, S.
10.1101/2024.02.28.582460 — Posted: 2024-02-28
HyDrop: droplet-based scATAC-seq and scRNA-seq using dissolvable hydrogel beads
De Rop, F. V., Ismail, J. N., Bravo Gonzalez-Blas, C., Hulselmans, G. J., Flerin, C. C., Janssens, J., Theunis, K., Christiaens, V. M., Wouters, J., Marcassa, G., de Wit, J., Poovathingal, S., Aerts, S.
10.1101/2021.06.04.447104 — Posted: 2021-06-06
Proportion and distribution of neurotransmitter-defined cell types in the ventral tegmental area and substantia nigra pars compacta
Conrad, W. S., Oriol, L., Faget, L., Hnasko, T. S.
10.1101/2024.02.28.582356 — Posted: 2024-02-28
Systemic inflammation triggers long-lasting neuroinflammation and accelerates neurodegeneration in a rat model of Parkinson's disease overexpressing human alpha-synuclein
Massaro Cenere, M., Tiberi, M., Paldino, E., D'Addario, S. L., Federici, M., Giacomet, C., Cutuli, D., Matteocci, A., Cossa, F., Zarrilli, B., Casadei, N., Ledonne, A., Petrosini, L., Berretta, N., Fusco, F. R., Chiurchiu, V., Mercuri, N. B.
10.1101/2024.01.30.577912 — Posted: 2024-03-25
Alpha-synuclein aggregates trigger anti-viral immune pathways and RNA editing in human astrocytes
D'Sa, K., Choi, M. L., Wagen, A. Z., Seto-Salvia, N., Kopach, O., Evans, J. R., Rodrigues, M., Lopez-Garcia, P., Ghareeb, A., Bayne, J., Grant-Peters, M., Garcia-Ruiz, S., Chen, Z., Rodriques, S., Athauda, D., Gustavsson, E., Gagliano Taliun, S. A., Reynolds, R. H., Young, G., Strohbuecker, S., Warner, T., Rusakov, D. A., Patani, R., Bryant, C., Klenerman, D. A., Gandhi, S., Ryten, M.
10.1101/2024.02.26.582055 — Posted: 2024-02-28
Visualizing chaperone-mediated multistep assembly of the human 20S proteasome
Adolf, F., Du, J., Goodall, E. A., Walsh, R. M., rawson, S., von Gronaua, S., Harper, J. W., Hanna, J., Schulman, B. A.
10.1101/2024.01.27.577538 — Posted: 2024-01-28

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