Channel:  Aligning Science Across Parkinson's (ASAP)

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

335 Articles

Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2G2019S model of Parkinson's disease
Gaertner, Z., Oram, C., Schneeweis, A., Schonfeld, E., Bolduc, C., Chen, C., Dombeck, D. A., Parisiadou, L., Poulin, J. F., Awatramani, R.
10.1101/2024.06.06.597807 — Posted: 2024-12-22
Dopamine and cortical iPSC-derived neurons with different Parkinsonian mutations show variation in lysosomal and mitochondrial dysfunction: implications for protein deposition versus selective cell loss
Chedid, J., Li, Y., Labrador-Garrido, A., Abu-Bonsrah, D., Pavan, C., Fraser, T., Ovchinnikov, D., Zhong, M., Davis, R., Strbenac, D., Johnston, J. A., Thompson, L. H., Kirik, D., Parish, C., Halliday, G., Sue, C., Wali, G., Dzamko, N.
10.1101/2024.10.07.617117 — Posted: 2024-11-11
RNApysoforms: Fast rendering interactive visualization of RNA isoform structure and expression in Python
Heberle, B. A., Page, M. L., Gustavsson, E. K., Ryten, M., Ebbert, M. T. W.
10.1101/2024.11.06.622357 — Posted: 2024-11-08
Autophagic stress activates distinct compensatory secretory pathways in neurons
Palumbos, S. D., Popolow, J., Goldsmith, J., Holzbaur, E.
10.1101/2024.11.07.621551 — Posted: 2024-11-07
Striatal lateral inhibition regulates action selection in a mouse model of levodopa-induced dyskinesia
Twedell, E. L., Bair-Marshall, C. J., Girasole, A. E., Scaria, L. K., Sridhar, S., Nelson, A. B.
10.1101/2024.10.11.617939 — Posted: 2024-11-01
Inhibition of Indirect Pathway Activity Causes Abnormal Decision-Making In a Mouse Model of Impulse Control Disorder in Parkinson's Disease
Zhuang, X., Lemak, J., Sridhar, S., Nelson, A. B.
10.1101/2024.02.19.581062 — Posted: 2024-11-01
Hydrophobic tails enable diverse functions of the extracellular chaperone clusterin
Yuste-Checa, P., Carvajal, A. I., Chenchen, M., Paatz, S., Hartl, F.-U., Bracher, A.
10.1101/2024.10.30.620894 — Posted: 2024-10-31
Type-II kinase inhibitors that target Parkinson's Disease-associated LRRK2
Raig, N. D., Surridge, K. J., Sanz-Murillo, M., Dederer, V., Kramer, A., Schwalm, M. P., Elson, L., Chatterjee, D., Mathea, S., Hanke, T., Leschziner, A. E., Reck-Peterson, S. L., Knapp, S.
10.1101/2024.09.17.613365 — Posted: 2024-10-31
A Protocol for Neuralized Murine Olfactory Organoids
Ozgun, A., Suman, P., Coulombe, J., aSCENT-PD Investigators, , Brown, E. G., Tomlinson, J. J., Woulfe, J. M., Schlossmacher, M. G.
10.1101/2024.10.29.620938 — Posted: 2024-10-31
Proportion and distribution of neurotransmitter-defined cell types in the ventral tegmental area and substantia nigra pars compacta
Conrad, W. S., Oriol, L., Kollman, G. J., Faget, L., Hnasko, T. S.
10.1101/2024.02.28.582356 — Posted: 2024-10-30

RSS  Channel RSS