Channel:  Aligning Science Across Parkinson's (ASAP)

522 Articles

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A guanosine nucleotide metabolism-bioenergetics intersection drives Parkinson's disease
Kokotos, A. C., Unda, S. R., Reyes-Perez, P. R., Isayan, M., Perinan, M. T., Kaplitt, M. G., Ryan, T. A.
10.64898/2026.07.29.741503 — Posted: 2026-08-04
A lipid transfer-dependent feedback loop activates ATG9A compartments in autophagy initiation
Holzer, E., Sawa-Makarska, J., Bernklau, D., Romanov, J., Schuschnig, M., Martens, S.
10.1101/2025.08.16.670665 — Posted: 2026-08-04
Cholesterol Dysregulation in APOE4 Astrocytes Promotes α-Synuclein Pathology in miBrains, a Human Brain Tissue Model
Mesentier-Louro, L. A., Goldman, C., Gaese, S., Buonfiglioli, A., Kyriakis, D., Harlock, A., Ndayisaba, A., Sartori, E. R., Uchitelev, A., Fullard, J. F., Hennigan, E., Lee, D., Schuldt, B. R., Rooklin, R. B., Barra, J., Bravo-Cordero, J. J., Roussos, P., Khurana, V., Blanchard, J. W.
10.1101/2025.02.09.637107 — Posted: 2026-08-04
Health phenome of Parkinson's patients reveals prominent mood-sleep cluster
Olsen, A. L., Locascio, J. J., Tuncali, I., Laroussi, N., Abatzis, E., Kamenskaya, P., Kuras, Y., Yi, T., Videnovic, A., Hayes, M. T., Ho, G. P. H., Paulson, J., Khurana, V., Herrington, T. M., Hyman, B. T., Selkoe, D. J., Growdon, J. H., Gomperts, S. N., Riise, T., Schwarzschild, M. A., Hung, A. Y., Wills, A.-M., Scherzer, C. R.
10.1101/2022.02.01.22270276 — Posted: 2026-08-03
Time Course and Microcircuit Mechanisms of Primary Motor Cortex Dysfunction in Progressive Parkinsonism
Chen, L., Chehade, H. D., Somavarapu, S., Chu, H.-Y.
10.64898/2026.07.27.741031 — Posted: 2026-07-30
Structural Mechanisms of DNAJC13 Dimeric Assembly and InsP6 binding in Recycling Endosome Regulation
Fu, T., Lee, C., Hundley, F. V., Paulo, J. A., Harper, J. W.
10.64898/2026.07.28.740790 — Posted: 2026-07-29
Cerebrospinal fluid profile, including α-Synuclein seeding activity, of p.A53T SNCA mutation carriers: Data from the PPMI Study.
Simitsi, A. M., Papagiannakis, N., Alefanti, I., Piccilo, M., Barone, P., Lafontant, D.-E., Marek, K., Siderowf, A., Simuni, T., Koros, C., Stefanis, L.
10.64898/2026.07.23.26356817 — Posted: 2026-07-27
Isolation and Lipidomic Profiling of Neuronal Lipid Droplets: Unveiling the Lipid Landscape of Neurodegenerative Disorders
Kumar, M., Mcallister, R., Roy, S., Knapp, J., Gupta, K., Ryan, T. A.
10.1101/2023.12.13.571527 — Posted: 2026-07-23
Activation of transposable elements is linked to a region- and cell-type-specific interferon response in Parkinson's disease
Garza, R., Adami, A., Thiruvalluvan, A., Wijesinghe, S., Curle, A. J., Tam, O., Forcier, T., Lagka, D. A., Kazakou, N. L., Atacho, D. A. M., Sharma, Y., Horvath, V., Bermudez, S., Johansson, J. G., Rainbow, D. B., Castilla-Vallmanya, L., Jones, J. L., Quaegebeur, A., Gale Hammell, M., Kirkeby, A., Barker, R. A., Jakobsson, J.
10.1101/2025.09.03.673956 — Posted: 2026-07-15
Identifying Blood Proteomic Markers of Parkinson's Disease Dementia Using High-Throughput Approaches
Real, R., Ravazio, R., Nodehi, A., Ben-Shlomo, Y., Williams, N., Barros, R. C., Grosset, D., Hu, M., Winchester, L., Morris, H.
10.64898/2026.06.30.26356774 — Posted: 2026-07-10

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