Channel: Fred Hutchinson Cancer Center

This collection includes bioRxiv and medRxiv papers from authors at Fred Hutchinson Cancer Center.

1345 Articles

Histone H3K27 methylation states are sequentially catalyzed in cycling cells

Greene, J. E., Ahmad, K., Henikoff, S.

10.64898/2026.04.30.721988 — Posted: 2026-05-04

Induction of multiple HIV-1 neutralizing B Cell Precursors in Humans

Yeh, C.-H., Walsh, S. R., Parsons, R., Zhang, E., Thakur, B., Song, K., Van ltallie, E., Clark, M., Williams, W. B., Edwards, R. J., Hahn, W. O., Song, S., Lin, L., Huang, H.-I., Lugo, J., Quan, A., Xue, Y., chen, Y., Ryan, T., Mansouri, K., Spence, T., Laukaitis, H., Parks, R., Barr, M., Schweer, E., Levering, N., Eaton, A., Shen, S., Janowska, K., Johnson, G., Wang, P., Cain, D. W., Arus-Altuz, A., Donahue, E., Kirshner, H. F., Zhbannikov, I., Berry, M., Venkatayogi, S., Martin Beem, J. S., Hyrien, O., Yu, P.-C., Parks, R. K., Polakowski, L. L., Tindale, I., Yurdadon, C., Burnham, R., Andrie

10.64898/2026.05.02.26352058 — Posted: 2026-05-04

Integrin-independent Tie2 activation using de novo designed proteins

McCurdy, C., Zhao, Y. T., Kumar, S., Coventry, B., Pink, A., Fu, Y., Bohn, P., Zhu, S., Goreshnik, I., Wang, X., Ruth, G., Ravichandran, R., Mathieu, J., Cooper, J. A., Fuller, D. H., Kim, H. M., Saharinen, P., Baker, D., Ruohola-Baker, H.

10.64898/2026.05.01.718274 — Posted: 2026-05-02

Polygenic predisposition modifies the associations of fish oil supplementation with circulating omega-3 fatty acids: a cross-sectional gene-diet interaction study in UK Biobank

Xu, H., Yu, G., Lu, Y., Fuller, H., Song, S., Shen, Y., Chiang, C. W. K., Darst, B. F., Ye, K.

10.64898/2026.04.29.26352078 — Posted: 2026-04-30

Patient CACNA1A variant uncouples calcium channel conductance from synaptic output

Krawchuk, M. B., Tiroumalechetty, A., Zuluaga-Forero, M., Augustine, A., Dong, Y., Jackson, N., Jen, J. C., Snell, H. D., Bai, J., Spray, D. C., Kurshan, P. T.

10.64898/2026.04.27.721138 — Posted: 2026-04-29

Structural basis of broadly neutralizing human antibodies targeting diverse dengue virus forms.

Mangala Prasad, V., Chatterjee, A., Roy, A., Srinivasan, S., Charles, S., Lubow, J., goo, l.

10.64898/2026.02.07.704521 — Posted: 2026-04-27

Human lung γδ T cells maintain functionality during inflammatory lung disease

Taber, A., Frutoso, M., Potchen, N., Koehne, A. L., Schmitz, C., Morrell, E. D., Prlic, M., Wright, S. W.

10.64898/2026.04.23.720435 — Posted: 2026-04-27

Designed Minibinders Rewire Receptor Signaling to Enable Functional Human Myogenic Reprogramming

Keshri, R., Foreman, Z., Barrett, P., Robinson, A. J., Reyes, G., Phal, A. A., Krishnakumar, A., Narog, E., Chiu, M., Jain, S., Wang, X., Lee, D., Exposit, M., Abedi, M., Smith, A. S. T., Srivatsan, S. R., Shendure, J., Mathieu, J., Mack, D. L., Baker, D., Ruohola-Baker, H.

10.64898/2026.04.26.720818 — Posted: 2026-04-27

De novo design of a macrocycle induced dimerization system for cellular control

Baker, D., Hanna, S., Salveson, P., Wicky, B., Kennedy, M., Hicks, D., Moller, C., Cheng, S., Li, X., Abedi, M., Coventry, B., Said, M., Bera, A. K., Kang, A., Stoddard, B. L.

10.64898/2026.04.24.720480 — Posted: 2026-04-26

Racioethnic Disparities in Risk of Cardiometabolic Risk Factors and Cardiovascular Disease among Women Treated for Breast Cancer: The Pathways Heart Study

Yao, S., Zimbalist, A., Sheng, H., Fiorica, P., Cheng, R., Medicino, L., Omilian, A., Zhu, Q., Roh, J., Laurent, C., Lee, V., Ergas, I., Iribarren, C., Rana, J., Nguyen-Huynh, M., Rillamas-Sun, E., Hershman, D., Ambrosone, C., Kushi, L., Greenlee, H., Kwan, M.

10.64898/2026.04.23.26351612 — Posted: 2026-04-24

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