Channel: Fred Hutchinson Cancer Center

This collection includes bioRxiv and medRxiv papers from authors at Fred Hutchinson Cancer Center.

1035 Articles

Spatiotemporal dynamics of tumor-CAR T-cell interaction following local administration in solid cancers

Owens, K., Rahman, A., Bozic, I.

10.1101/2024.08.29.610392 — Posted: 2024-10-01

Damage-induced IL-18 stimulates thymic NK Cells limiting endogenous tissue regeneration

Granadier, D., Cooper, K., Kousa, A., Acenas, D., Lemarquis, A., Hernandez, V., Warren, M., Iovino, L., deRoos, P., Lederer, E., Shannon-Sevillano, S., Kinsella, S., Evandy, C., van den Brink, M., Dudakov, J.

10.1101/2024.09.27.615528 — Posted: 2024-09-30

Integrator complex subunit 12 knockout overcomes a transcriptional block to HIV latency reversal

Gray, C. N., Ashokkumar, M., Janssens, D. H., Kirchherr, J. L., Allard, B., Hsieh, E., Hafer, T. L., Archin, N. M., Browne, E. P., Emerman, M.

10.1101/2024.08.30.610517 — Posted: 2024-09-28

Multimodal Spatial Profiling Reveals Immune Suppression and Microenvironment Remodeling in Fallopian Tube Precursors to High-Grade Serous Ovarian Carcinoma

Kader, T., Lin, J.-R., Hug, C., Coy, S., Chen, Y.-A., de Bruijn, I., Shih, N., Jung, E., Pelletier, R. J., Leon, M. L., Mingo, G., Omran, D. K., Lee, J. S., Yapp, C., Satravada, B. A., Kundra, R., Xu, Y., Chan, S., Tefft, J., Muhlich, J. L., Kim, S., Gysler, S. M., Agudo, J., Heath, J. R., Schultz, N., Drescher, C., Sorger, P. K., Drapkin, R., Santagata, S.

10.1101/2024.09.25.615007 — Posted: 2024-09-27

Endocrine persistence in ER+ breast cancer is accompanied by metabolic vulnerability in oxidative phosphorylation

Tau, S., Chamberlin, M. D., Yang, H., Marotti, J. D., Roberts, A. M., Carmichael, M. M., Cressey, L., Dragnev, C. P., Demidenko, E., Hampsch, R. A., Soucy, S. M., Kolling, F. W., Samkoe, K. S., Alvarez, J. V., Kettenbach, A., Miller, T. W.

10.1101/2024.09.26.615177 — Posted: 2024-09-27

Recognition of phylogenetically diverse pathogens through enzymatically amplified recruitment of RNF213

Crespillo-Casado, A., Pothukuchi, P., Naydenova, K., Yip, M. C. J., Young, J. M., Boulanger, J., Dharamdasani, V., Harper, C., Hammoudi, P.-M., Otten, E. G., Boyle, K. B., Gogoi, M., Malik, H. S., Randow, F.

10.1101/2024.09.24.614677 — Posted: 2024-09-26

Genetic Variation and Regulation of MICA Alters Natural Killer Cell-Mediated Immunosurveillance in Early-Onset Colorectal Cancer

McGee, H. M., Bonner, J., Egelston, C., Fu, Y., Flores, O., Lindsey, S., Shaktah, L., Moratalla-Navarro, F., Kamal, Y., Tsang, K., Walker, C. P., Idos, G., McDonnell, K., Rennert, H., Barry, E., Brenner, H., Buchanan, D., Campbell, P., Chan, A., Claude, J., Figueiredo, J. C., Dominguez, M., Hoffmeister, M., Hsu, L., Huyghe, J. R., Jenkins, M., Le Marchand, L., Lenz, H., Li, L., Lindblom, A., Liu, Y.-R., Lynch, B., Newton, C., Offit, K., Ogino, S., Sanz Pamplona, R., Pellatt, A., Pharoah, P., Phipps, A. I., Reynaga, L., Templeton, A., Um, C., Wolk, A., Woods, M., Wu, A., Yun, Y., Zheng, W., Wil

10.1101/2024.09.22.24314127 — Posted: 2024-09-26

MAX inactivation deregulates the MYC network and induces neuroendocrine neoplasia in multiple tissues

Freie, B., Ibrahim, A. H., Carroll, P. A., Bronson, R. T., Augert, A., MacPherson, D., Eisenman, R. N.

10.1101/2024.09.21.614255 — Posted: 2024-09-24

Developmental regulation of endothelial-to-hematopoietic transition from induced pluripotent stem cells

Wellington, R., Cheng, X., Campbell, C. A., Trapnell, C., Espin-Palazon, R., Hadland, B., Doulatov, S.

10.1101/2024.09.24.612755 — Posted: 2024-09-24

Classifying cell cycle states and a quiescent-like G0 state using single-cell transcriptomics

O'Connor, S. A., Garcia, L., Patel, A. P., Bartelle, B. B., Hugnot, J.-P., PADDISON, P., Plaisier, C. L.

10.1101/2024.04.16.589816 — Posted: 2024-09-22

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