Channel: Fred Hutchinson Cancer Center

This collection includes bioRxiv and medRxiv papers from authors at Fred Hutchinson Cancer Center.

1098 Articles

Long-Term Carotid Plaque Progression and the Role of Intraplaque Hemorrhage: Analysis from Deep Learning-based Longitudinal Vessel Wall Imaging

Guo, Y., Akcicek, E. Y., Hippe, D. S., HashemizadehKolowri, S., Wang, X., Akcicek, H., Canton, G., Balu, N., Geleri, D. B., Kim, T., Shibata, D., Zhang, K., Ma, X., Ferguson, M. S., Mossa-Basha, M., Hatsukami, T. S., Yuan, C.

10.1101/2024.12.09.24318661 — Posted: 2025-02-19

Succinate Dehydrogenase loss causes cascading metabolic effects that impair pyrimidine biosynthesis

Hart, M. L., Davidsen, K., Danquah, S., Zheng, E., Sokolov, D., Sullivan, L. B.

10.1101/2025.02.18.638948 — Posted: 2025-02-19

Whole genome sequence-based association analysis of African American individuals with bipolar disorder and schizophrenia

Li, R., Gagliano Taliun, S. A., Liao, K. L., Flickinger, M., Sobell, J. L., Genovese, G., Locke, A. E., Chiu, R. R., LeFaive, J., Wang, J., Martins, T. M., Chapman, S. B., Neumann, A., Handsaker, R. E., Arnett, D. K., Barnes, K. C., Boerwinkle, E., Braff, D., Cade, B. E., Fornage, M., Gibbs, R. A., Hoth, K. F., Hou, L., Kooperberg, C., Loos, R. J. F., Metcalf, G. A., Montgomery, C. G., Morrison, A. C., Qin, Z. S., Redline, S., Reiner, A. P., Rich, S. S., Rotter, J. I., Taylor, K. D., Viaud-Martinez, K. A., NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, , Genomic Psychiatry Coho

10.1101/2024.12.27.24319111 — Posted: 2025-02-19

Integrator complex subunit 12 knockout overcomes a transcriptional block to HIV latency reversal

Gray, C. N., Ashokkumar, M., Janssens, D. H., Kirchherr, J. L., Allard, B., Hsieh, E., Hafer, T. L., Archin, N. M., Browne, E. P., Emerman, M.

10.1101/2024.08.30.610517 — Posted: 2025-02-19

A Syntenic Pangenome for Gardnerella Reveals Taxonomic Boundaries and Stratification of Metabolic and Virulence Potential across Species

Bouzek, H., Srinivasan, S., Jones, D. S., McMahon, E. F., Strenk, S. M., Fiedler, T. L., Fredricks, D. N., Johnston, C. D.

10.1101/2025.02.19.636902 — Posted: 2025-02-19

Image-based identification and isolation of micronucleated cells to dissect cellular consequences

DiPeso, L., Pendyala, S., Huang, H. Z., Fowler, D. M., Hatch, E. M.

10.1101/2023.05.04.539483 — Posted: 2025-02-18

Defined cellular reprogramming of androgen receptor-active prostate cancer to neuroendocrine prostate cancer

Li, S., Song, K., Sun, H., Tao, Y., Huang, A., Bhatia, V., Hanratty, B., Patel, R. A., Long, H. W., Morrissey, C., Haffner, M. C., Nelson, P. S., Graeber, T. G., Lee, J. K.

10.1101/2025.02.12.637904 — Posted: 2025-02-17

Defined media reveals the essential role of lipid scavenging to support cancer cell proliferation

Newsom, O. J., Sullivan, L. B.

10.1101/2025.02.12.637975 — Posted: 2025-02-17

Accuracy and Scalability of Machine Learning Methods for Genotype-Phenotype Association Data

Collienne, K., Zhang, L., Gavryushkin, A.

10.1101/2025.02.13.638022 — Posted: 2025-02-17

CARD8 inflammasome activation during HIV-1 cell-to-cell transmission

Kulsuptrakul, J., Emerman, M., Mitchell, P. S.

10.1101/2024.08.21.608981 — Posted: 2025-02-15

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