Channel: Fred Hutchinson Cancer Center

This collection includes bioRxiv and medRxiv papers from authors at Fred Hutchinson Cancer Center.

1082 Articles

Classifying cell cycle states and a quiescent-like G0 state using single-cell transcriptomics

O'Connor, S. A., Garcia, L., Hoover, R. L., Patel, A. P., Bartelle, B. B., Hugnot, J.-P., PADDISON, P., Plaisier, C. L.

10.1101/2024.04.16.589816 — Posted: 2025-01-15

A fast numerical integration scheme for clonal expansion processes on graphs

Paterson, C. G. B., Gao, M., Hellier, J., Luebeck, G., Wedge, D. C., Bozic, I.

10.1101/2025.01.13.632690 — Posted: 2025-01-15

Combinatorial phenotypic landscape enables bacterial resistance to phage infection

Gupta, A., Morella, N., Sutormin, D., Li, N., Gaisser, K., Robertson, A., Ispolatov, Y., Seelig, G., Dey, N., Kuchina, A.

10.1101/2025.01.13.632860 — Posted: 2025-01-15

Correlates and Consequences of Clonal Hematopoiesis Expansion Rate: A 15-Year Longitudinal Study of 6,986 Women

Pershad, Y., Uddin, M. M., Xue, L., Haessler, J., Collins, J. M., Mack, T. M., Glick, E., Glaser, V., Zhao, K., Jaiswal, S., Manson, J. E., Pandey, U., Desai, P., Natarajan, P., Honigberg, M. C., Kooperberg, C. L., Whitsel, E. A., Kitzman, J., Bick, A. G., Reiner, A. P.

10.1101/2025.01.12.25320422 — Posted: 2025-01-13

The mutation rate of SARS-CoV-2 is highly variable between sites and is influenced by sequence context, genomic region, and RNA structure

Haddox, H. K., Angehrn, G., Sesta, L., Jennings-Shaffer, C., Temple, S. D., Galloway, J. G., DeWitt, W. S., Bloom, J. D., Matsen, F. A., Neher, R. A.

10.1101/2025.01.07.631013 — Posted: 2025-01-08

Metagenomic estimation of absolute bacterial biomass in the mammalian gut through host-derived read normalization.

Tang, G., Carr, A. V., Perez, C., Ramos Sarmiento, K., Levy, L., Lampe, J., Diener, C., Gibbons, S. M.

10.1101/2025.01.07.631807 — Posted: 2025-01-08

Image-based identification and isolation of micronucleated cells to dissect cellular consequences

DiPeso, L., Pendyala, S., Huang, H. Z., Fowler, D. M., Hatch, E. M.

10.1101/2023.05.04.539483 — Posted: 2025-01-07

Multi-species analysis of inflammatory response elements reveals ancient and lineage-specific contributions of transposable elements to NF-κB binding

Wang, L., Taylor, T., Rathnakumar, K., Khyzha, N., Liang, M., Alizada, A., Campitelli, L., Pour, S. E., Patel, Z. M., Antounians, L., Tobias, I. C., Hughes, T., Roy, S., Mitchell, J. A., Fish, J. E., Wilson, M. D.

10.1101/2022.10.25.513724 — Posted: 2024-12-30

Whole genome sequence-based association analysis of African American individuals with bipolar disorder and schizophrenia

Li, R., Gagliano Taliun, S. A., Liao, K. L., Flickinger, M., Sobell, J. L., Genovese, G., Locke, A. E., Chiu, R. R., LeFaive, J., Martins, T. M., Chapman, S. B., Neumann, A., Handsaker, R. E., Arnett, D. K., Barnes, K. C., Boerwinkle, E., Braff, D., Cade, B. E., Fornage, M., Gibbs, R. A., Hoth, K. F., Hou, L., Kooperberg, C., Loos, R. J. F., Metcalf, G. A., Montgomery, C. G., Morrison, A. C., Qin, Z. S., Redline, S., Reiner, A. P., Rich, S. S., Rotter, J. I., Taylor, K. D., Viaud-Martinez, K. A., NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, , Genomic Psychiatry Cohort investi

10.1101/2024.12.27.24319111 — Posted: 2024-12-29

Inflammatory Monocytes Increase Prior to Detectable HIV-1 Rebound Viremia

Farrell-Sherman, A., de la Force, N., Prator, C., Valieris, R., Azam, W., Silva, I., Deeks, S., Thanh, C., Bosch, R., Henrich, T. J., Cohn, L. B.

10.1101/2024.12.24.630257 — Posted: 2024-12-25

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