Channel: Albert Einstein College of Medicine

This collection includes bioRxiv and medRxiv papers from authors at Albert Einstein College of Medicine.

1188 Articles

Whole blood transcriptional signatures of age and survival identified in Long Life Family and Integrative Longevity Omics Studies

Li, M., Song, Z., Reed, E., Karagiannis, T. T., Andersen, S., Brent, M., Mateusiak, C., Acharya, S., Jung, W. S., Liao, S., Wojczynski, M. K., Feitosa, M. F., O'Connell, J. R., Montasser, M. E., Thorpe, R. J., Arbeev, K., Milman, S., Tai, A., Perls, T. T., Sebastiani, P., Monti, S.

10.1101/2025.07.15.664976 — Posted: 2026-01-06

Transcriptional Heterogeneity Reveals a Synaptic Gene Program in Developing and Adult Human Oligodendrocyte Precursor Cells

Grinberg, A. R., Liu, L., Patel, I., Guntur, B., Glass, I. A., Birth Defects Research Laboratory, , Shinoda, K., Nobuta, H.

10.64898/2026.01.01.697017 — Posted: 2026-01-02

Expression of the human immunomodulatory protein, human B7-1 (CD80), accelerates neuroinflammation, synaptic loss, microvascular instability and lethality in a murine model of Alzheimers Disease

Danelon, V., Garrett-Thomson, S., Morano, N., Constanza, R., Kermani, P., Smith, R., Almo, S. C., Lee, F. S., Hempstead, B. L.

10.64898/2025.12.30.697078 — Posted: 2025-12-31

Age- and Sex-Adjusted Myocardial Flow Reserve Percentiles for Personalized Cardiovascular Risk Assessment

Joseph, L., Trinquart, L., Lopez, D. M., Soares Brandao, S., Brown, J. M., Divakaran, S., Huck, D., Weber, B. N., Barrett, L., Hainer, J., Carre, S., Lemley, M., Ramirez Orozco, G., Liang, J., Blankstein, R., Dorbala, S., Alexanderson, E., Carvajal-Juarez, I., Acampa, W., Packard, R., Le, V., Mason, S., Knight, S., Chareonthaitawee, P., Wopperer, S., Rosamond, T., Buechel, R. R., Einstein, A. J., Al-Mallah, M. H., Slipczuk, L., Travin, M. I., Berman, D., Dey, D., Slomka, P., Di Carli, M. F.

10.64898/2025.12.30.25343223 — Posted: 2025-12-31

Structural, biophysical, and virological mechanistic characterization of HIV-1 capsid-targeting antivirals

Kirby, K. A., McFadden, W. M., Wang, L., Du, H., Zhang, H., Emanuelli Castaner, A., Lorson, Z. C., Nafisi, A., Luchsinger, C., Hachiya, A., Cilento, M. E., Snyder, A. A., Ravichandran, S. M., Cai, X., Tedbury, P. R., Francis, A. C., Melikyan, G. B., Diaz-Griffero, PhD, F. R., Wang, Z., Sarafianos, S. G.

10.64898/2025.12.30.696960 — Posted: 2025-12-31

Heterogeneous epigenetic variation converges on splicing dysregulation in opioid addiction

Qureshi, F., Apere, C., Okeke, C., Lambert, T., Evans, V., Sallari, R., Chakraborty, M., Morgan, L., Barnard, Z., Luna, X., Madden, M., Rotti, P. G., Hoang, A., Ramcharan, H. K., Quach, B., Maher, B. S., Willis, C., Mash, D., Scacheri, P. C., Johnson, E., Akbarian, S., Corradin, O.

10.64898/2025.12.20.25342745 — Posted: 2025-12-29

Neocortical long-range inhibition promotes cortical synchrony and sleep

Ratliff, J. M., Terral, G., Vazquez Lechuga, A., Lutzu, S., Manning, A., Perez Catalan, N., Neubert da Silva, G., Kim, S., Mota, J., Mallory, M., Stith, B., Ramakrishnan, C. M., Mattessich, G., Fenno, L. E., Daigle, T., Stafford, D. A., Zeng, H., Tasic, B., Sorensen, S., Deisseroth, K., Ngai, J., Kilduff, T., Sjulson, L., Rudolph, S., Batista-Brito, R.

10.1101/2024.06.20.599756 — Posted: 2025-12-24

Direct measurement of sub-kilobase chromatin structure reveals that linker histone H1 broadly compacts chromatin, with differential impact amongst epigenetic states

Canaj, H., Duba, I., Mansisidor, A., Scortea, A., Johnson, R., Pinto, H., Ou, A., Pagane, N., Pae, J., Fyodorov, D., Skoultchi, A. I., Risca, V. I.

10.64898/2025.12.19.695525 — Posted: 2025-12-23

A Comparison of Two Deep Learning Approaches to Distinguish Functional Dissociative from Epileptic Seizures Using Event Videos

Erekat, A. N., Dakov, M., Cheung, J., Mackenzie, M., Malerba, S., Lefkovitz, I., Chan, A. H. W., Hwang, J., Richter, F., Gleason, A., Marcuse, L., Fields, M., Glicksberg, B. S., Nadkarni, G., Jette, N., Kummer, B. R.

10.64898/2025.12.18.25342568 — Posted: 2025-12-19

Romaciclib, a CDK8/CDK19 inhibitor, can overcome venetoclax resistance through a combinatorial strategy

Pakulska, U., Obacz, M., Woznicki, J., Wiklik, K., Chakraborty, S., Micek, M., Mohanty, V., Coelho, D., Adamczyk, E., Golas, A., Moszynska, A., Zhang, H., Cybulska-Lubak, M., Kaniuga, E., Sadowska-Markiewicz, Z., Konopleva, M., Mikula, M., Juszczynski, P., Shastri, A., Baran, N., Rzymski, T., Mazan, M.

10.64898/2025.12.16.693978 — Posted: 2025-12-18

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