Channel:  The Howard Hughes Medical Institute (HHMI)

1,971 Articles

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LipidCruncher: An open-source platform for processing, visualizing, and analyzing lipidomic data
Abdi, H., Ambaw, Y., Lai, Z. W., Ly, R., Chitraju, C., Singh, S., Farese, R., Walther, T. C.
10.1101/2025.04.28.650893 — Posted: 2026-01-30
Frequency dynamics predict viral fitness, antigenic relationships and epidemic growth
Figgins, M. D., Bedford, T.
10.1101/2024.12.02.24318334 — Posted: 2026-01-29
Molecular determinants of antibody-mediated priming to enhance detection of ctDNA
Tabrizi, S., Sullivan, C., Chakraborty, K., Martin-Alonso, C., An, Z., Gao, L., Kim, D. M., Patel, S. K., Blewett, T., Rhoades, J., Liu, R., Patel, S., Xiong, K., Crnjac, A., Bhatia, S. N., Adalsteinsson, V. A., Love, J. C.
10.64898/2026.01.27.701975 — Posted: 2026-01-29
SAGA1 and SAGA2 localize the starch sheath to the pyrenoid in Chlamydomonas reinhardtii
Crans, V. L., Burton, M. I., Garde, A., Wang, L., Jonikas, M. C.
10.64898/2026.01.27.702031 — Posted: 2026-01-29
Social sensing of infection reprograms peripheral immunity in healthy mice
Ademolue, T. W., Pernas, L. F.
10.64898/2026.01.28.702380 — Posted: 2026-01-29
Spyglass: a framework for reproducible and shareable neuroscience research
Lee, K. H., Denovellis, E. L., Ly, R., Magland, J., Soules, J., Comrie, A. E., Gramling, D. P., Guidera, J. A., Nevers, R., Adenekan, P., Brozdowski, C., Bray, S. R., Monroe, E., Bak, J. H., Coulter, M., Sun, X., Broyles, E., Shin, D., Chiang, S., Holobetz, C., Tritt, A., Ruebel, O., Nguyen, T., Yatsenko, D., Chu, J., Kemere, C., Garcia, S., Buccino, A., Frank, L. M.
10.1101/2024.01.25.577295 — Posted: 2026-01-29
Leptin Receptor+ cells create a perisinusoidal niche for thrombopoiesis in the bone marrow by synthesizing CXCL14
Xue, y., Merchant, S., Reyes, A., Luo, M., Zhang, R., Tippetts, T., Grabowski, G., Ngo, T., Zhang, Y., Shang, Z., Jiang, N., Jeffery, E., Li, Y., Wei, T., Gu, W., Du, L., DeBerardinis, R. J., Dean, K. M., Mathews, T. P., Lucas, D. P., Zhao, Z., Morrison, S. J.
10.64898/2026.01.27.702029 — Posted: 2026-01-28
A molecularly defined basalo-prefrontal-thalamic circuit regulates sensory and affective dimensions of pain in male mice
Xie, G., Liu, Y., Qi, X., Bhattacherjee, A., Zhang, C., Zhang, Y.
10.1101/2025.08.22.671771 — Posted: 2026-01-28
MDA5 multimerization on LINE RNA drives pathogenic extracellular immune complexes in autoimmunity
Hsu, T. Y.-T., Wang, X., Isayama, Y., Jung, V., Zhang, J., van Gompel, E., Maadadi, H., Torres, C., Shimazaki-Takahashi, A., Kurihara, N., Kondo, M., Galesic, M., Notarnicola, A., Sultana, S., Maeda, A., Vleugels, R. A., Dellaripa, P. F., Yamashita, T., Ito, Y., Awaji, K., Kotani, H., Matsuda, K. M., Horuluogu, B., Grönwall, C., Joshua, V., Ukai, Y., Hosomi, N., Wagner, D. D., Lundberg, I. E., Kato, K., Hur, S.
10.64898/2026.01.27.702129 — Posted: 2026-01-28
De novo design of phosphotyrosine peptide binders
Bauer, M. S., Zhang, J. Z., Wu, K., Lee, G. R., Coventry, B., Silvestri, I. M., Klupt, K. A., Shi, J., Brent, R. I., Li, X., Moller, C., Roullier, N., Vafeados, D. K., Kalvet, I., Skotheim, R. K., Zhu, S., Motmaen, A., Herrmann, L. C., Sturmfels, P., Tischer, D., Altae-Tran, H., Juergens, D., Krishna, R., Ahern, W., Yim, J., Bera, A. K., Kang, A., Joyce, E., Lu, A., Stewart, L., DiMaio, F., Mudumbi, K. C., Baker, D.
10.1101/2025.09.29.678898 — Posted: 2026-01-28

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