Channel:  International Mouse Phenotyping Consortium (IMPC)

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

96 Articles

Impact of Essential Genes on the Success of Genome Editing Experiments Generating 3,313 New Genetically Engineered Mouse Lines
Elrick, H., Peterson, K. A., Willis, B. J., Lanza, D. G., Acar, E. F., Ryder, E. J., Teboul, L., Kasparek, P., Birling, M.-C., Adams, D. J., Bradley, A., Braun, R. E., Brown, S. D., Caulder, A., Codner, G. F., DeMayo, F. J., Dickinson, M. E., Doe, B., Duddy, G., Gertsenstein, M., Goodwin, L. O., Herault, Y., Lintott, L. G., Lloyd, K. C. K., Lorenzo, I., Mackenzie, M., Mallon, A.-M., McKerlie, C., Parkinson, H., Ramirez-Solis, R., Seavitt, J. R., Sedlacek, R., Skarnes, W. C., Wells, S., Smedley, D., White, J. K., Wood, J. A., International Mouse Phenotyping Consortium, , Murray, S. A., Heaney
10.1101/2021.10.06.463037 — Posted: 2024-03-21
IRG1 controls host responses to restrict Mycobacterium tuberculosis infection
Machelart, A., Belhaouane, I., Deboosere, N., Poncin, I., Saint-Andre, J.-P., Pauwels, A.-M., Song, O.-R., Jouny, S., Rouanet, C., Poncet, A., Marion, S., Laine, W., Kluza, J., Muraille, E., Beyaert, R., Majlessi, L., Canaan, S., Brodin, P., Hoffmann, E.
10.1101/761551 — Posted: 2022-05-04
Transcriptome-wide Association Study and eQTL colocalization identify potentially causal genes responsible for bone mineral density GWAS associations
Al-Barghouthi, B. M., Rosenow, W. T., Du, K.-P., Heo, J., Maynard, R., Mesner, L., Calabrese, G., Nakasone, A., Senwar, B., Gerstenfeld, L., Ferguson, V., Ackert-Bicknell, C., Morgan, E., Brautigan, D. L., Farber, C. R.
10.1101/2021.10.12.464046 — Posted: 2022-01-23
MusMorph, a database of standardized mouse morphology data for morphometric meta-analyses
Devine, J., Vidal-Garcia, M., Liu, W., Neves, A., Lo Vercio, L. D., Green, R. M., Richbourg, H. A., Marchini, M., Unger, C. M., Nickle, A. C., Radford, B., Young, N. M., Gonzalez, P. N., Schuler, R. E., Bugacov, A., Rolian, C., Percival, C. J., Williams, T., Niswander, L., Calof, A. L., Lander, A. D., Visel, A., Jirik, F. R., Cheverud, J. M., Klein, O. D., Birnbaum, R. Y., Merrill, A. E., Ackermann, R. R., Graf, D., Hemberger, M., Dean, W., Forkert, N. D., Murray, S. A., Westerberg, H., Marcucio, R. S., Hallgrimsson, B.
10.1101/2021.11.11.468142 — Posted: 2021-11-12
Collagen (I) homotrimer potentiates the osteogenesis imperfecta (oim) mutant allele and reduces survival in male mice
Lee, K. J., Rambault, L., Bou-Gharios, G., Clegg, P. D., Akhtar, R., Czanner, G., van 't Hof, R. J., Canty-Laird, E. G.
10.1101/2020.07.13.198283 — Posted: 2021-11-09
Prevalent mouse phenotypes in the unexplored druggable genome
Gulyaeva, O., Hu, Z., Oprea, T. I., Lloyd, K., Gomez, S. M., Roth, B. L., McManus, M.
10.1101/2021.11.08.467777 — Posted: 2021-11-08
Whole genome analysis for 163 guide RNAs in Cas9 edited mice reveals minimal off-target activity
Peterson, K. A., Khalouei, S., Woodd, J. A., Lanza, D. G., Lintott, L. G., Willis, B. J., Seavitt, J. R., Hanafi, N., Braun, R. E., Dickinson, M. E., White, J. K., Lloyd, K. C. K., Heaney, J., Murray, S. A., Ramani, A., Nutter, L. M.
10.1101/2021.08.11.455876 — Posted: 2021-08-11
Systems genetics analyses in Diversity Outbred mice inform human bone mineral density GWAS and identify Qsox1 as a novel determinant of bone strength
Al-Barghouthi, B. M., Mesner, L. M., Calabrese, G. M., Brooks, D. J., Tommasini, S. M., Bouxsein, M. L., Horowitz, M. C., Rosen, C. J., Nguyen, K., Haddox, S., Farber, E. A., Onengut-Gumuscu, S., Pomp, D., Farber, C.
10.1101/2020.06.24.169839 — Posted: 2021-03-14
MRI of Capn15 knockout mice and analysis of Capn15 distribution reveal possible roles in brain development and plasticity
Zha, C., Farah, C. A., Fonov, V., Rudko, D., Sossin, W. S.
10.1101/763888 — Posted: 2021-03-10
Widespread cryptic variation in genetic architecture between the sexes
van der Bijl, W., Mank, J. E.
10.1101/2021.02.20.432102 — Posted: 2021-02-20

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