Channel: University of Massachusetts Chan Medical School

This collection includes bioRxiv and medRxiv papers from authors at University of Massachusetts Chan Medical School .

991 Articles

A brown fat-enriched adipokine, ASRA, is a leptin receptor antagonist that stimulates appetite

Huang, L., Liu, P., Du, Y., Bazan, J. F., Pan, D., Chen, Q., Lee, A., Rao Kola, V. S., Wolfe, S., Wang, Y.-X.

10.1101/2023.09.12.557454 — Posted: 2024-11-17

Inpp5e Is Critical for Photoreceptor Outer Segment Maintenance

Gupta, M., Lewis, T. R., Stuck, M. W., Spencer, W. J., Klementieva, N. V., Arshavsky, V. Y., Pazour, G. J.

10.1101/2024.08.27.609873 — Posted: 2024-11-12

A consensus variant-to-function score to functionally prioritize variants for disease

Fabiha, T., Evergreen, I., Kundu, S., Pampari, A., Abramov, S., Boytsov, A., Strouse, K., Dura, K., Fang, W., Kerner, G., Butts, J., Ali, T., Gschwind, A., Mualim, K. S., Moore, J. E., Weng, Z., Ulirsch, J., Ji, H. E., Vierstra, J., Reddy, T. E., Montgomery, S. B., Engreitz, J., Kundaje, A., Tewhey, R., Price, A., Dey, K.

10.1101/2024.11.07.622307 — Posted: 2024-11-10

RNA/DNA Binding Protein TDP43 Regulates DNA Mismatch Repair Genes with Implications for Genome Stability

Provasek, V., Bacolla, A., Rangaswamy, S., Mitra, J., Kodavati, M., Yusuf, I., Malojirao, V., Vasquez, V., Britz, G. W., Li, G.-M., Xu, Z., Mitra, S., Garruto, R. M., Tainer, J., Hegde, M.

10.1101/2024.05.16.594552 — Posted: 2024-11-08

A type-specific B cell epitope at the apex of Outer surface protein C (OspC) of the Lyme disease spirochete, Borreliella burgdorferi

Vance, D., Freeman-Gallant, G., McCarthy, K., Piazza, C. L., Chen, Y., Vorauer, C., Muriuki, B., Rudolph, M. J., Cavacini, L., Guttman, M., MANTIS, N. J.

10.1101/2024.11.06.622094 — Posted: 2024-11-08

Cocaine, via ΔFosB, remodels gene expression and excitability in ventral hippocampus

Eagle, A. L., Doyle, M. A., Sugimoto, C., Dykstra, M. M., Kuhn, H. M., Murray, B. R., Bastle, R. M., He, J., Maze, I., Mazei-Robison, M., Robison, A. J.

10.1101/2024.11.06.621895 — Posted: 2024-11-07

Rational Design of Enhanced Nme2Cas9 and Nme2SmuCas9 Nucleases and Base Editors

Bamidele, N., Ansodaria, A., Chen, Z., Cheng, H., Panwala, R., Jazbec, E., Sontheimer, E. J.

10.1101/2024.10.30.620986 — Posted: 2024-11-07

Suppression of Huntington's Disease Somatic Instability by Transcriptional Repression and Direct CAG Repeat Binding

Mathews, E. W., Coffey, S. R., Gaertner, A., Belgrad, J., Bragg, R. M., O'Reilly, D., Cantle, J. P., McHugh, C., Summers, A., Fentz, J., Schwagarus, T., Cornelius, A., Lingos, I., Burch, Z., Kovalenko, M., Andrew, M. A., Bennett, C. F., Kordasiewicz, H., Marchionini, D. M., Wilkinson, H., Vogt, T. F., Pinto, R. M., Khvorova, A., Howland, D., Wheeler, V., Carroll, J. B.

10.1101/2024.11.04.619693 — Posted: 2024-11-04

Mouse Pachytene piRNAs Cleave Hundreds of Transcripts,But Alter the Steady-State Abundance of Only a Minority of Targets

Cecchini, K., Ajaykumar, N., Bagci, A., Zamore, P., Gainetdinov, I.

10.1101/2024.11.02.621675 — Posted: 2024-11-03

Executive Functioning and Processing Speed as Predictors of Global Cognitive Decline in Alzheimer Disease

Haran, J. P., Barrett, A., Lai, Y., Odjidja, S., Dutta, P., McGrath, P. M., Samari, I., Romeiro, L., Lopes, A., Bucci, V., McCormick, B. A.

10.1101/2024.10.31.24316508 — Posted: 2024-11-02

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