Channel: University of Massachusetts Chan Medical School

This collection includes bioRxiv and medRxiv papers from authors at University of Massachusetts Chan Medical School .

975 Articles

New Statistical Metric for Robust Target Detection in Cryo-EM Using 2DTM

Zhang, K., Cossio, P., Rangan, A. V., Lucas, B. A., Grigorieff, N.

10.1101/2024.10.01.616095 — Posted: 2024-10-03

Potent and durable gene modulation in heart and muscle with chemically defined siRNAs

Fakih, H. H., Lochmann, C., Gagnon, R., Summers, A., Caiazzi, J., Buchwald, J. E., Tang, Q., Maru, B., Hildebrand, S. R., Zain UI Abideen, M., Furgal, R. C., Gross, K. Y., Yang, Y.-S., Cooper, D., Monopoli, k., Echeverria, D., Shim, J.-h., Yamada, K., Alterman, J. F., Khvorova, A.

10.1101/2024.10.01.616183 — Posted: 2024-10-03

Transcriptome-based identification of long noncoding RNAs (lncRNAs) across the genome of Anopheles gambiae

Xu, J., Hu, K., Riehle, M. M., Khadka, V.

10.1101/2024.10.02.616138 — Posted: 2024-10-03

Real-Time Spatiotemporal Tracking of Infectious Outbreaks in Confined Environments with a Host-Pathogen Agent-Based System

Srinivasan, S., King, J., Colubri, A., Korkin, D.

10.1101/2024.10.01.616085 — Posted: 2024-10-03

Early zygotic engineering promotes targeted large transgene integration and direct production of fully transgenic animals

Gupta, K., Xu, P., Gallant, J., Yoon, Y., Rivera-Perez, J. A., Lawrence, J. B.

10.1101/2024.09.29.615605 — Posted: 2024-10-01

An aneuploidy epistasis map reveals metabolic vulnerabilities associated with supernumerary chromosomes in cancer

Magesh, R. Y., Kaur, A. N., Keller, F. N., Frederick, A., Tseyang, T., Haley, J. A., Rivera Nieves, A. M., Liang, A. C., Guertin, D., Spinelli, J., Elledge, S. J., Watson, E. V.

10.1101/2024.09.30.615609 — Posted: 2024-10-01

A unique interplay of access and selection shapes peritoneal metastasis evolution in colorectal cancer

Wassenaar, E. C., Gorelick, A. N., Hung, W.-T., Cheek, D. M., Kucukkose, E., Lee, I.-H., Blohmer, M., Degner, S., Giunta, P., Wiezer, R. M., Raicu, M. G., Ubink, I., Klaasen, S. J., Lansu, N., Watson, E. V., Corcoran, R. B., Boland, G., Getz, G., Kops, G. J., Juric, D., Lennerz, J. K., Boerma, D., Kranenburg, O., Naxerova, K.

10.1101/2024.09.25.614736 — Posted: 2024-09-27

Frequency of Variants in Mendelian Alzheimer's Disease Genes within the Alzheimer's Disease Sequencing Project (ADSP)

Wang, D., Scalici, A., Wang, Y., Lin, H., Pitsillides, A., Heard-Costa, N., Cruchaga, C., Ziegemeier, E., Bis, J. C., Fornage, M., Boerwinkle, E., De Jager, P. L., Wijsman, E., Dupuis, J., Renton, A. E., Seshadri, S., Goate, A. M., The Alzheimer's Disease Sequencing Project, , DeStefano, A. L., Peloso, G. M.

10.1101/2023.10.24.23297227 — Posted: 2024-09-23

Population genomics of Plasmodium ovale species in sub-Saharan Africa

Carey-Ewend, K., Popkin-Hall, Z. R., Simkin, A., Muller, M., Hennelly, C., He, W., Moser, K., Gaither, C., Niare, K., Aghakanian, F., Feleke, S., Brhane, B. G., Phanzu, F., Mwandagalirwa, K., Aydemir, O., Sutherland, C., Ishengoma, D. S., Ali, I. M., Ngasala, B., Kalonji, A., Tshefu, A., Parr, J., Bailey, J. A., Juliano, J. J., Lin, J. T.

10.1101/2024.04.10.588912 — Posted: 2024-09-19

An integrated view of the structure and function of the human 4D nucleome

The 4D Nucleome Consortium, , Dekker, J., Oksuz, B. A., Zhang, Y., Wang, Y., Minsk, M. K., Kuang, S., Yang, L., Gibcus, J. H., Krietenstein, N., Rando, O., Xu, J., Janssens, D. H., Henikoff, S., Kukalev, A., Willemin, A., Winick-Ng, W., Kempfer, R., Pombo, A., Yu, M., Kumar, P., Zhang, L., Belmont, A. S., Sasaki, T., van Schaik, T., Brueckner, L., Peric-Hupkes, D., van Steensel, B., Wang, P., Chai, H., Kim, M., Ruan, Y., Zhang, R., Quinodoz, S. A., Bhat, P., Guttman, M., Zhao, W., Chien, S., Liu, Y., Venev, S. V., Plewczynski, D., Irastorza Azcarate, I., Szabo, D., Thieme, C. J., Szczepinska

10.1101/2024.09.17.613111 — Posted: 2024-09-19

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