Channel:  The Howard Hughes Medical Institute (HHMI)

2,331 Articles

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Dystrophic changes of nigrostriatal axons harboring a Synj1 Parkinson mutation suggest catastrophic failure of endocytic mechanisms
Wu, Y., Xu, P., Moran, J., Xu, C. S., Hayworth, K., Cao, M., Shao, L., Surmeier, D. J., Hess, H., De Camilli, P.
10.64898/2026.06.24.733515 — Posted: 2026-06-29
Maternal experience alters brain-wide representation of infant cries
McRae, B. R., Ferguson, D.-L. K. D., Swanier, K., Allen, G. I., Marlin, B. J.
10.64898/2026.06.26.734581 — Posted: 2026-06-28
The genomic origins and evolutionary path to a key innovation in the world's most venomous snakes
van Thiel, J., Dowell, N., Smith, C. F., Sanchez, E. E., Carroll, S.
10.64898/2026.06.23.733212 — Posted: 2026-06-28
The type VI secretion system governs strain maintenance in a wild mammalian gut microbiome
Shen, B. A., Asfahl, K. L., Lim, B., Bertolli, S. K., Minot, S. S., Radey, M. C., Penewit, K., Ngo, B., Salipante, S. J., Johnston, C. D., Peterson, S. B., Goodman, A. L., Mougous, J. D.
10.1101/2025.11.29.690828 — Posted: 2026-06-26
Development of GS-441524 Derivatives as Potent SARS-CoV-2 Mac1 Inhibitors via a Direct-to-Biology Approach
Peng, K., Chakraborty, S., Wallace, S. D., Noll, J. C. G., Shang, J., Lu, X., Choi, A., Whittaker, G., Fromme, J. C., Lin, H.
10.64898/2026.06.24.734322 — Posted: 2026-06-25
Structural Basis of Human Kinetochore-Microtubule Coupling by the Ndc80 and Ska Complexes
Zhou, J., Saha, I., Siahaan, V., Zhao, Y., Janke, C., Yildiz, A., Nogales, E.
10.64898/2025.12.06.692780 — Posted: 2026-06-25
PARP1 Exhibits an Enzymatically Inactive Chromatin Binding Mode
Fiorenza, A., Anand, M., Luger, K.
10.64898/2026.06.24.734344 — Posted: 2026-06-25
Parabrachial Ntsr1 neurons modulate food intake and anxiety through a projection to the ventromedial hypothalamus
Pauli, J. L., Park, S., Felix, R. R., Palmiter, R.
10.64898/2026.03.03.709382 — Posted: 2026-06-24
Structural variant discovery and diagnostic impact in rare diseases from short-read and long-read sequencing
Sanchis-Juan, A., Mostovoy, Y., Stenton, S. L., Ganesh, V. S., Weisburd, B., Yenkin, A., Kurtas, N. E., Zhao, X., Shin, E., Boone, P. M., Su, H., Lee, A. S., Yadav, R., Allan, K., Argilli, E., Austin-Tse, C., Barry, B. J., Baxter, S., Beggs, A. H., Bell, K. M., Blankenmeister, B., Bönnemann, C. G., Brownstein, C. A., Bujakowska, K. M., Carbonell, E., Cooper, S. T., Covill, L. E., DiTroia, S., Donkervoort, S., Engle, E. C., Gallacher, L., Genetti, C. A., Gleeson, J. G., Guan, B., Hall, S., Hildebrandt, F., Hufnagel, R. B., Jurgens, J. A., Khorgade, A., Lemire, G., Liau, E., Ma, J., Madden, J.
10.64898/2026.06.22.26356238 — Posted: 2026-06-24
ESCRT-0 regulates AMPA receptor currents and Ca2+- dependent signaling
Pourhamzeh, M., Dozier, L., Wilpitz, A., Du, Y., McClatchy, D. B., Micael, M. K. B., Mayfield, J. E., Gilmore-Hall, S. K., Ronson, J. E., Soldau, K., Pizzo, D. P., Aulston, B., Sullivan, E. E., Shay, T. F., Wang, J., Roy, S., Gradinaru, V., Trotter, J. H., Dore, K., Yates, J. R., Patrick, G. N., Sigurdson, C. J.
10.64898/2026.06.19.733273 — Posted: 2026-06-24

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