Channel:  The Howard Hughes Medical Institute (HHMI)

2,381 Articles

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Genome-wide chromatin recording resolves dynamic cell state changes
Takei, Y., Lay, J. A., Linton, J. M., Chadly, D. M., Ochiai, Y., Hadas, R., Perez, A. A., Blanco, M. R., Laurino, P., Guttman, M., Elowitz, M. B.
10.1101/2025.08.05.668773 — Posted: 2026-07-19
Human vault RNAs exhibit diverse expression patterns and inter-locus compensation
Hemphill, W. O., Zaug, A. J., Hecht, C. J. S., Cech, T. R.
10.64898/2026.06.17.732918 — Posted: 2026-07-18
Stepwise DNA unwinding gates TnpB genome-editing activity
Zhou, Z., Saffarian-Deemyad, I., Shi, H., Weiss, T., ur-Rehman, M. M., Vohra, K., Skopintsev, P., Yoon, P. H., Trinidad, M. I., Langeberg, C. J., Kamalu, M., Amerasekera, J., Zhou, Y., Doherty, E. E., Aris, K. D. P., Al-Sayyad, N., Thornton, B. W., Weissman, R. F., Wasko, K. M., Esain-Garcia, I., DeTurk, E. C., Savage, D. F., Jacobsen, S. E., Bryant, Z., Doudna, J. A.
10.64898/2026.01.09.698545 — Posted: 2026-07-18
Nanopore-based profiling of PEGylation in nucleic acid therapeutics
Patino Guillen, G., Schmidt, T. T., Baumberg, J. J., Szostak, J. W., Keyser, U. F., Boskovic, F.
10.64898/2025.12.15.694309 — Posted: 2026-07-17
Projectomic Organization of the Serotonin System of the Mouse Brain
Song, J. H., Friedmann, D., Wu, Y., Moses, A., Baruni, J. K., Yuan, Y., Rana, I., Zhao, K., Hindmarsh Sten, T., Wang, Q., Xiao, S. A., Chen, X., Linderman, S. W., Luo, L.
10.64898/2026.07.15.738594 — Posted: 2026-07-17
Comprehensive Lineage Tracing Maps the Landscape of Cell Fate Decisions in Mouse Embryogenesis
Colgan, W. N., Koblan, L. W., Villagrana, J., Hou, T.-C. J., Wang, M., Gowri, G., Chandler, W., Sepulveda, L. A., Ciftci, D., Smolyar, K., Young, A., Wittler, L., Markoulaki, S., Loh, K. M., Zhuang, X., Yosef, N., Smith, Z. D., Weissman, J. S.
10.64898/2026.05.07.722278 — Posted: 2026-07-17
Whole-body single-cell atlas of an adult vertebrate in homeostasis and regeneration
Atabay, K. D., Aoude, P., Park, C., Kadobianskyi, M., Paugois, O. H., Judkewitz, B., Reddien, P.
10.64898/2026.02.03.703562 — Posted: 2026-07-17
Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins
Jiang, M., Li, Y., Artyukhova, M., Zhang, L., Luo, S., Zhan, W., Zhang, B., Gokce, O., Sudhof, T. C.
10.64898/2026.07.15.738748 — Posted: 2026-07-17
Transcriptomic data and biomedical literature synergize in finding pharmacologic gene regulators
Deisseroth, C. A., Brazelton, B., Shaik, Z., Sandberg, B. S., Liu, Z., Zoghbi, H. Y.
10.64898/2026.03.13.708862 — Posted: 2026-07-17
Nextstrain automates real-time phylogenetic analysis of open data for endemic and emerging pathogens
Andrews, K. R., Chang, J., Roemer, C., Hadfield, J., Lin, V., Brito, A. F., Daodu, R., Joia, I. A., Kistler, K., Li, A. W., Moncla, L. H., Paredes, M. I., Kuhnert, D., Torres, L. M., Voitl, L., Aksamentov, I., Hodcroft, E. B., Huddleston, J., McCrone, J. T., Anderson, J. S., Sibley, T. R., Lee, J., Neher, R. A., Bedford, T.
10.64898/2026.03.23.713807 — Posted: 2026-07-17

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