Channel:  The Howard Hughes Medical Institute (HHMI)

2,765 Articles

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FACT frees Ubp10 from nucleosome sequestration after rapid H2B deubiquitination
Merino-Urteaga, R., Zaehringer, J., Nune, M., Wolberger, C., Ha, T.
10.64898/2026.11.06.765004 — Posted: 2026-11-09
A subtype-specific gene regulatory program controls differential circuit integration of deep CA3 pyramidal neurons
Daaboul, D., Vandensteen, J., Dascenco, D., Lorente-Echeverria, B., Vandenbempt, J., Leysen, E., Reverendo, M., Vlaeminck, I., Vervloessem, L., Alcaraz, N., Wojno, M., Poovathingal, S., Davie, K., Magalhaes, P., Kempynck, N., Michel, G., Spruston, N., Wierda, K., Aerts, S., de Wit, J.
10.64898/2026.11.03.763963 — Posted: 2026-11-07
Near real-time data on the human neutralizing antibody landscape to influenza virus in summer of 2026 shows antigenic advance of H3N2 subclade K region D mutants and H1N1 D.3.1.1 Sa mutants
Kikawa, C., Butler, A., Huddleston, J., Turner, S. A., Peck, H., Englund, J. A., Lacombe, K., Busch, M., Lanteri, M. C., Stone, M., Spencer, B., Greninger, A. L., Smith, D. J., Wallace, S., Marshall, H. S., Tosif, S., Hensley, S. E., Barr, I. G., Bloom, J. D.
10.64898/2026.09.15.751855 — Posted: 2026-11-07
High-throughput identification of chromatin-opening transcription factors
Keith, A., Jain, S., Daza, R. M., Qiu, C., Germain, P.-L., Shendure, J., Domcke, S.
10.64898/2026.10.07.757445 — Posted: 2026-11-07
Massive inter-animal horizontal gene transfer contributes to stress tolerance in the fungus gnat Bradysia coprophila
Kapoor, R. R., Kumar, T., Nanda, P., Phuangphong, S., Murray, A. W., Extavour, C. G.
10.64898/2026.11.06.764122 — Posted: 2026-11-06
Motivation-dependent communication between cortex and brainstem
Machado, T. A., Chen, Y., Beiran, M., Subramanian, M., Kadur, C., Bradbury, S., Nix, K., Liu, B., Rajan, K., Deisseroth, K.
10.64898/2026.11.05.764652 — Posted: 2026-11-06
Single-cell multi-omics identify OTP and NOVA1 as regulators of leptin action in hypothalamic feeding circuits
Tan, H. L., Tan, Y., Ruiz-Ortiz, J., Paul, M., Han, Z., Kelly, L., Toci, A., Plucinska, K., Tajima, Y., Shiao, R., Lee, B., Ilanges, A., Darnell, R. B., Cohen, P., Friedman, J. M.
10.64898/2026.11.04.764326 — Posted: 2026-11-06
Druggable CSNK2A1-MeCP2 regulatory axis links Okur-Chung neurodevelopmental syndrome with MECP2-related disorders
Anderson, A. G., Chamakuri, S., Meyer-Schuman, R., Chu, E. H.-Y., Revelli, J.-P., Kim, J., Zaghlula, M., Veeraragavan, S., Young, D. W., Zoghbi, H. Y.
10.64898/2026.11.05.764603 — Posted: 2026-11-06
Tree shrews combine panoramic vision with an expanded oculomotor repertoire
Pal, R., Kempkes, E., Aeleti, R., Tubbs, E., Biswas, A., Sedigh-Sarvestani, M.
10.64898/2026.10.23.761344 — Posted: 2026-11-06
A reporter mouse model to map RIG-I expression and function in vivo
Ehrenzeller, S. A., Hinesley, A. C., Borunda, S., Liu, S., Richards, D. O., Kwon, D.-i., Mehrmann, T. M., Phillbrick, W. M., Thoresen, D. T., Flavell, R. A., Pyle, A. M., Iwasaki, A.
10.64898/2026.11.04.764288 — Posted: 2026-11-06

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