Channel:  The Howard Hughes Medical Institute (HHMI)

1,285 Articles

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De novo design of metal-oxide templating proteins
Saragovi, A., Pyles, H., Huddy, T. F., Li, X., Borst, A. J., Hanikel, N., Courbet, A., Kwon, P., Davila-Hernandez, F. A., Kibler, R. D., Vafeados, D. K., Allen, A., Carr, K. D., Bera, A., Kang, A., Brackenbrough, E., Schmid, S., Bae, Y., Stewart, L., Zhang, S., De Yoreo, J., Baker, D.
10.1101/2024.06.24.600095 — Posted: 2025-11-01
Specialized parallel pathways for adaptive control of visual object pursuit
Collie, M. F., Jin, C., Rockwell, V., Kellogg, E., Vanerbeck, Q. X., Hartman, A. K., Holtz, S. L., Wilson, R. I.
10.1101/2025.04.23.650240 — Posted: 2025-11-01
Spatiotemporal lineage tracing reveals the dynamic spatial architecture of tumor growth and metastasis
Jones, M. G., Sun, D., Min, K. H., Colgan, W. N., Wang, H., Török, T., Cardoso, E. C., Tian, L., Weir, J. A., Chen, V. Z., Koblan, L. W., Yost, K. E., Mathey-Andrews, N., D'Souza, E., Russell, A. J. C., Stickels, R. R., Balderrama, K. S., Rideout, W. M., Dai, M., Marrero, G., Kumar, V., Saqi, A., Herzberg, B., Izar, B., Chang, H. Y., Lee, J.-H., Jacks, T., Chen, F., Weissman, J. S., Yosef, N., Yang, D.
10.1101/2024.10.21.619529 — Posted: 2025-10-24
Engineering compact Physalis peruviana (goldenberry) to promote its potential as a global crop
Santo Domingo, M., Fitzgerald, B., Robitaille, G. M., Ramakrishnan, S., Swartwood, K., Karavolias, N., Schatz, M., Van Eck, J., Lippman, Z.
10.1101/2025.08.15.670557 — Posted: 2025-10-24
The Kaposi's sarcoma-associated herpesvirus TBP mimic uses a non-canonical DNA binding mode to promote viral late gene transcription
Llacsahuanga Allcca, L. E., Didychuk, A. L., Rodriguez-Vargas, A., Glaunsinger, B.
10.1101/2025.08.25.672222 — Posted: 2025-10-23
SPEECHLESS duplication in grasses expands potential for environmental regulation of stomatal development
Erberich, J. M., Bennett, B., Bergmann, D.
10.1101/2025.07.29.667563 — Posted: 2025-10-21
Progenitor-Derived Regulatory Logic Generates Functionally Related Neuronal Subtypes
Xu, C., Sastry, R., Newstein, P., Delgado, R., Wagh, N., Silies, M., Cepko, C. L., Doe, C.
10.1101/2024.09.27.615552 — Posted: 2025-10-20
Accelerating protein design by scaling experimental characterization
Qian, J., Milles, L. F., Wicky, B. I. M., Ragotte, R. J., Motmaen, A., Borst, A. J., Skotheim, R., Ols, S., Coventry, B., Li, X., Kibler, R. D., Goreshnik, I., Exposit, M., Lore, K., Stewart, L., Baker, D.
10.1101/2025.08.05.668824 — Posted: 2025-10-16
Assessment of Nucleic Acid Structure Prediction in CASP16
Kretsch, R. C., Hummer, A. M., He, S., Yuan, R., Zhang, J., Karagianes, T., Cong, Q., Kryshtafovych, A., Das, R.
10.1101/2025.05.06.652459 — Posted: 2025-10-16
Mapping cellular targets of covalent cancer drugs in the entire mammalian body
Pang, Z., Leung, V. H., Wang, C. C., Attarpour, A., Rinaldi, A., Shen, H., Moya-Garzon, M. D., Sigua, L. H., Rammel, C., Selke, A., Glynn, C., Yender, M., Xu, S., Moslehi, J. J., Wu, P., Long, J. Z., Goubran, M., Cravatt, B. F., Ye, L.
10.1101/2025.03.28.645991 — Posted: 2025-10-14

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