Channel:  Aligning Science Across Parkinson's (ASAP)

529 Articles

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Elevated phosphorylated α-synuclein and phosphorylated tau in Lrrk2 p.G2019S-mutant mice following influenza A pneumonitis
Lunn, M. O., Thakur, K., Lengacher, N. A., Hake-Volling, Q., aSCENT-PD Investigators, , Tomlinson, J. J., Sad, S., Brown, E. G., Schlossmacher, M. G.
10.1101/2025.07.31.667659 — Posted: 2026-09-19
Sex-stratified analysis of the potential association between PGLYRP2 rs892145 variant and Parkinson's disease across diverse ancestral populations
Avila, C. L., Chaparro Solano, H. M., Quintana-Pena, V., Aberg, K., the Global Parkinson's Genetics Program (GP2), , Atterling Brolin, K.
10.1101/2025.07.23.25331993 — Posted: 2026-09-15
Impulse Control Disorders Are Independent of Parkinson Disease Motor Subtypes
Chhotani, M. E., Saban, W., Rossi, M., Kuo, S.-H., Montaser-Kouhsari, L., Lin, C.-Y. R., Parkinsons Precision Medicine Initiative
10.64898/2026.09.04.26362266 — Posted: 2026-09-08
Network analysis of α-synuclein pathology progression reveals p21-activated kinases as regulators of vulnerability
Vatsa, N., Brynildsen, J. K., Goralski, T. M., Kurgat, K., Meyerdirk, L., Breton, L., DeWeerd, D., Brasseur, L., Turner, L., Becker, K., Gallik, K. L., Isaguirre, C., Sheldon, R. D., Bassett, D. S., Henderson, M. X.
10.1101/2024.10.22.619411 — Posted: 2026-09-04
Dermal Phospho-Alpha-Synuclein Among Individuals With and Without Cerebrospinal Fluid Aggregated Alpha-Synuclein
Chahine, L., Chatterjee, K., Gochanour, C., Lafontant, D.-E., Akhtar, R., Shetty, N., Dahodwala, N., Brooker, S., Gonzalez-Latapi, P., Prakash, N., Defendorf, S., Midyette, J., Foroud, T., Merchant, K., Coughlin, D., Tropea, T. F., Frasier, M., Larson, D., Coffey, C., Marek, K., Simuni, T.
10.64898/2025.12.17.25342090 — Posted: 2026-09-02
The LRRK2 R1441G+M1646T haplotype is associated with slower motor symptom progression in Parkinson's disease
Schumacher, J. G., Zhang, X., Wang, J., Chen, X.
10.64898/2026.08.26.26361428 — Posted: 2026-08-31
ClC-7 links PIKfyve inhibition to Rab-dependent LRRK2 activity at lysosomes
Clegg, D., Bentley-DeSousa, A., Roczniak-Ferguson, A., Ferguson, S. M.
10.1101/2025.11.19.689251 — Posted: 2026-08-29
Connectomic dopamine-neuron disinhibition accelerates behavioral extinction
Burwell, S. C. V., Carter, R. K., Yan, H., Lim, S. S. X., Shields, B. C., TADROSS, M. R.
10.64898/2026.08.24.746800 — Posted: 2026-08-27
Cross-trait and multi-polytranscriptomic score analysis of Parkinson's disease identifies novel associations and improves prediction
Gilchrist, L., Pain, O., Calhas, S., Genetics Program, G. P., Noyce, A. J., Atterling Brolin, K., Perinan, M. T., Proitsi, P.
10.64898/2026.08.21.26358780 — Posted: 2026-08-26
Genetic screening identifies glial adenosine as a therapeutic target in alpha-synucleinopathy
Sodders, M. J., Avila-Pacheco, J., Okorie, E. C., Tahmasebidehkordi, H., Marathi, A., Kumari, N., Lakhani, M., Schiro, A., Shen, M., Sriram, N., Sarkar, S., Olsen, A. L.
10.1101/2024.05.15.594309 — Posted: 2026-08-21

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