Channel:  Aligning Science Across Parkinson's (ASAP)

528 Articles

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Network analysis of α-synuclein pathology progression reveals p21-activated kinases as regulators of vulnerability
Vatsa, N., Brynildsen, J. K., Goralski, T. M., Kurgat, K., Meyerdirk, L., Breton, L., DeWeerd, D., Brasseur, L., Turner, L., Becker, K., Gallik, K. L., Isaguirre, C., Sheldon, R. D., Bassett, D. S., Henderson, M. X.
10.1101/2024.10.22.619411 — Posted: 2026-09-04
Dermal Phospho-Alpha-Synuclein Among Individuals With and Without Cerebrospinal Fluid Aggregated Alpha-Synuclein
Chahine, L., Chatterjee, K., Gochanour, C., Lafontant, D.-E., Akhtar, R., Shetty, N., Dahodwala, N., Brooker, S., Gonzalez-Latapi, P., Prakash, N., Defendorf, S., Midyette, J., Foroud, T., Merchant, K., Coughlin, D., Tropea, T. F., Frasier, M., Larson, D., Coffey, C., Marek, K., Simuni, T.
10.64898/2025.12.17.25342090 — Posted: 2026-09-02
The LRRK2 R1441G+M1646T haplotype is associated with slower motor symptom progression in Parkinson's disease
Schumacher, J. G., Zhang, X., Wang, J., Chen, X.
10.64898/2026.08.26.26361428 — Posted: 2026-08-31
ClC-7 links PIKfyve inhibition to Rab-dependent LRRK2 activity at lysosomes
Clegg, D., Bentley-DeSousa, A., Roczniak-Ferguson, A., Ferguson, S. M.
10.1101/2025.11.19.689251 — Posted: 2026-08-29
Connectomic dopamine-neuron disinhibition accelerates behavioral extinction
Burwell, S. C. V., Carter, R. K., Yan, H., Lim, S. S. X., Shields, B. C., TADROSS, M. R.
10.64898/2026.08.24.746800 — Posted: 2026-08-27
Cross-trait and multi-polytranscriptomic score analysis of Parkinson's disease identifies novel associations and improves prediction
Gilchrist, L., Pain, O., Calhas, S., Genetics Program, G. P., Noyce, A. J., Atterling Brolin, K., Perinan, M. T., Proitsi, P.
10.64898/2026.08.21.26358780 — Posted: 2026-08-26
Genetic screening identifies glial adenosine as a therapeutic target in alpha-synucleinopathy
Sodders, M. J., Avila-Pacheco, J., Okorie, E. C., Tahmasebidehkordi, H., Marathi, A., Kumari, N., Lakhani, M., Schiro, A., Shen, M., Sriram, N., Sarkar, S., Olsen, A. L.
10.1101/2024.05.15.594309 — Posted: 2026-08-21
ATG2A interacts with RAB1A and ARFGAP1 positive membranes during autophagosome biogenesis
Fuller, D. M., Wu, Y., Schueder, F., Rasool, B., Nag, S., Korfhage, J. L., Garcia-Milian, R., Melnyk, K. D., Bewersdorf, J., De Camilli, P., Melia, T. J.
10.1101/2025.03.24.645038 — Posted: 2026-08-20
Rise-and-fall dynamics reveal a molecular and cellular vulnerability axis in prion-like α-synuclein propagation
Alexandersen, C. G., Brynildsen, J. K., Prigent, A., Tamborrino, M., Mantziou, A., Kurgat, K., Henderson, M. X., Bassett, D. S.
10.64898/2026.03.27.714785 — Posted: 2026-08-19
Reconstitution of multistep recruitment of ULK1 to membranes in autophagy
Duan, Y., Lu, Y., Paul, S., Betz, J., Wilhelm, L. P., Cook, A. S. I., Ren, X., Adriaenssens, E., Martens, S., Ganley, I., Hummer, G., Hurley, J. H.
10.1101/2025.11.07.687251 — Posted: 2026-08-12

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