Channel:  Aligning Science Across Parkinson's (ASAP)

515 Articles

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5-HT4 receptor ligand RS67333 modulates striatal acetylcholine and dopamine release via inhibition of acetylcholinesterase
Qiao, Q., Wu, W., Cragg, S. J.
10.64898/2026.06.24.733606 — Posted: 2026-06-29
Striatal lateral inhibition regulates action selection in a mouse model of levodopa-induced dyskinesia
Twedell, E. L., Barnhill, O. K., Bair-Marshall, C. J., Girasole, A. E., Scaria, L. K., Sridhar, S., Nelson, A. B.
10.1101/2024.10.11.617939 — Posted: 2026-06-27
Repeat expansions in Parkinson's disease and parkinsonism across ancestries: insights from a global genetic cohort
Lange, L. M., Cerquera-Cleves, C., Tan, A.-H., Lim, S.-Y., Okubadejo, N. U., Lin, C.-H., Chen, P.-S., Shin, J. H., Ahmad-Annuar, A., Screven, L., Chelban, V., Dilliott, A. A., Fienemann, A., Ghosh Galvelis, K., Houlden, H. A., Iwaki, H., Jaunmuktane, Z., Cullinane, P. W., Warner, T., Junker, J., Kanana, Y., Keller Sarmiento, I. J., Klein, C., Kung, P.-J., Leonard, H. L., Mencacci, N. E., Nalls, M. A., Real, R., Ben Sassi, S., Trinh, J., Vitale, D., Westenberger, A., Wu, L., Singleton, A. B., Morris, H., Lohmann, K., Blauwendraat, C., Heutink, P., Fang, Z.-H., the Global Parkinson's Genetics Pr
10.64898/2026.06.12.26354932 — Posted: 2026-06-22
A single Citrobacter rodentium infection in Pink1 knockout and wild type mice leads to regional blood-brain-barrier perturbation and limited microglial activation without dopamine neuron axon terminal loss
Mukherjee, S., Grouza, V., Tchung, A., Even, A., Yaqubi, M., Tuznik, M., Cannon, T., Recinto, S. J., Gavino, C., Bourque, M.-J., Giguere, N., McBride, H. M., Desjardins, M., Gruenheid, S., Stratton, J. A., Rudko, D. A., Trudeau, L.-E.
10.1101/2024.12.24.630165 — Posted: 2026-06-17
Q-DOAS: A Proximity Quenching Assay for Real-Time Detection of Early Protein Aggregation Events
Kleczko, K. M., Gestaut, D., Dobbins, S., Abramovich, J., Sitron, C. S., Li, L., Chan, R., Wang, N., Yang, X. W., Hartl, F.-U., Frydman, J.
10.64898/2026.06.16.732424 — Posted: 2026-06-17
Striatal ensembles specify and control ongoing actions at fine motorresolution
Rodrigues-Vaz, I., Athalye, V. R., Rodrigues, H. F. M., Peterka, D. S., Costa, R. M.
10.64898/2025.12.03.692128 — Posted: 2026-06-12
Network analysis of α-synuclein pathology progression reveals p21-activated kinases as regulators of vulnerability
Vatsa, N., Brynildsen, J. K., Goralski, T. M., Kurgat, K., Meyerdirk, L., Breton, L., DeWeerd, D., Brasseur, L., Turner, L., Becker, K., Gallik, K. L., Isaguirre, C., Sheldon, R. D., Bassett, D. S., Henderson, M. X.
10.1101/2024.10.22.619411 — Posted: 2026-06-12
Structural Mechanism and Cellular Restriction of Tau Seeding from Endolysosomes
Herrmann, E., Tan, S., Rose, K. M., Hooy, R. M., Hurley, J. H.
10.64898/2026.06.08.731026 — Posted: 2026-06-10
Spermidine suppresses glial inflammation and parkinsonian abnormalities in ATP13A2 deficiency
Cascalho, A., Sati, A., Dhondt, H., Schoonvliet, N., Kaempf, N., Coccia, E., Mamalaki, A., Behrens, M. I., Brüggemann, N., Glatzel, M., Baekelandt, V., Klein, C., Eggermont, J., Verstreken, P., Blanchard, J., Vangheluwe, P.
10.64898/2026.05.23.26353575 — Posted: 2026-06-04
Structural basis for regulation of the proteasome 20S core particle by the Parkinsonism-associated proteins FBXO7 and PI31
Adolf, F., Goodall, E. A., Singh, E., von Gronau, S., Fermin Perez, E., Fung, D., Mueller, B. S., Paulo, J. A., Hanna, J., Harper, J. W., Schulman, B. A.
10.64898/2026.05.28.728263 — Posted: 2026-06-04

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