Channel:  Impact of Genomic Variation on Function (IGVF)

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

48 Articles

A machine-readable specification for genomics assays
Booeshaghi, A. S., Chen, X., Pachter, L.
10.1101/2023.03.17.533215 — Posted: 2023-07-18
Proximity Analysis of Native Proteomes Reveals Interactomes Predictive of Phenotypic Modifiers of Autism and Related Neurodevelopmental Conditions
Gao, Y., Trn, M., Shonai, D., Zhao, J., Soderblom, E. J., Garcia-moreno, S. A., Gersbach, C. A., Wetsel, W. C., Dawson, G., Velmeshev, D., Jiang, Y.-h., Sloofman, L. G., Buxbaum, J., Soderling, S. H.
10.1101/2022.10.06.511211 — Posted: 2023-06-23
A mutation rate model at the basepair resolution identifies the mutagenic effect of Polymerase III transcription
Seplyarskiy, V., Lee, D. J., Koch, E. M., Lichtman, J. S., Luan, H. H., Sunyaev, S. R.
10.1101/2022.08.20.504670 — Posted: 2023-05-17
Orthogonal CRISPR screens to identify transcriptional and epigenetic regulators of human CD8 T cell function
McCutcheon, S., Swartz, A., Brown, M., Barrera, A., McRoberts Amador, C., Siklenka, K., Humayun, L., Isaacs, J., Reddy, T. E., Nair, S., Antonia, S., Gersbach, C. A.
10.1101/2023.05.01.538906 — Posted: 2023-05-01
Modeling tissue co-regulation to estimate tissue-specific contributions to disease
Amariuta, T., Siewert-Rocks, K., Price, A. L.
10.1101/2022.08.25.505354 — Posted: 2023-03-26
Dynamic network-guided CRISPRi screen reveals CTCF loop-constrained nonlinear enhancer-gene regulatory activity in cell state transitions
Luo, R., Yan, J., Oh, J. W., Xi, W., Shigaki, D., Wong, W., Cho, H., Murphy, D., Cutler, R., Rosen, B. P., Pulecio, J., Yang, D., Glenn, R., Chen, T., Li, Q. V., Vierbuchen, T., Sidoli, S., Apostolou, E., Huangfu, D., Beer, M. A.
10.1101/2023.03.07.531569 — Posted: 2023-03-09
CHD-associated enhancers shape human cardiomyocyte lineage commitment
Armendariz, D. A., Goetsch, S. C., Sundarrajan, A., Sivakumar, S., Wang, Y., Xie, S., Munshi, N. V., Hon, G. C.
10.1101/2022.04.07.487515 — Posted: 2023-01-20
HiCLift: A fast and efficient tool for converting chromatin interaction data between genome assemblies
Wang, X., Yue, F.
10.1101/2023.01.17.524475 — Posted: 2023-01-20
Comparing Genomic and Epigenomic Features across Species Using the WashU Comparative Epigenome Browser
Zhuo, X., Hsu, S., Purushotham, D., Chen, S., Li, D., Wang, T.
10.1101/2022.11.29.518374 — Posted: 2022-12-02
EUGENe: A Python toolkit for predictive analyses of regulatory sequences
Klie, A., Stites, H., Jores, T., Solvason, J. J., Farley, E. K., Carter, H.
10.1101/2022.10.24.513593 — Posted: 2022-11-09

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