Channel: Yale University

This collection includes bioRxiv and medRxiv papers from authors at Yale University.

5276 Articles

Single-cell Pharmacogenomic Landscapes of Epigenetic Drug Resistance Revealed by Gastric Cancer Perturb-seq

Xu, C., Ma, H., Sheng, T., Lee, M. H., Abdul Ghani, S. A. B., Perlaza-Jimenez, L., Huang, K. K., Lim, S. K., Srivastava, S., Ong, X., Tay, S. T., Ho, S. W. T., Ong, Z. X., Tan, A. L. K., Zhu, F., Ashktorab, H., Cheng, A. S.-L., Jeyasekharan, A. D., Li, S., Teh, M., Sundar, R., Powell, D. R., Rosenbluh, J., Yong, W. P., So, J. B.-Y., Tan, P.

10.1101/2025.04.16.649236 — Posted: 2026-09-03

Evidence for long-standing mild-effect mutator alleles shaping genetic variation in S. cerevisiae populations

Jiang, P., Sudhesh, V., Phan, M. M.-N., Bansal, I., Wheeler, C., Herr, A. J., Dunham, M. J., Harris, K.

10.1101/2025.11.22.689970 — Posted: 2026-09-03

Cortical Hierarchy Dynamically Organizes Large-Scale Neural Propagation

Liu, X., Wan, B., Liu, W., Lu, R., Wang, S., Zhang, X., Dong, L., Fan, T.

10.64898/2026.08.29.747943 — Posted: 2026-09-03

Biased signaling via NtsR1 restrains food intake and weight gain in obese mice

Ramirez-Virella, J., Black, K., Dennis, N. F., Bugescu, R., Thompson, K., Olsen, S. H., Slosky, L. M., McElligott, Z. A., Leinninger, G. M.

10.64898/2026.08.30.748142 — Posted: 2026-09-03

Sobetirome, a thyroid hormone receptor beta agonist, is a potential therapeutic agent for pulmonary fibrosis

Barnthaler, T., Ding, s., Adams, T. S., Rose, K.-A., Rangel, R., Khoury, J., Salimi, M., Anderson, S., Lin, L., Velasco Alzate, K., Poli De Frias, F., Deluliis, G., Nicola, F., Cosme, C., Justet, A., Liu, X., Rosas, I., Kaminski, N., Ahangari, F.

10.64898/2026.08.31.747360 — Posted: 2026-09-03

Functional characterization of Rho GTPase activating proteins SYDE1 and SYDE2

Song, C., An, S., Lou, H. J., Turk, B. E.

10.64898/2026.08.31.748432 — Posted: 2026-09-03

Neogenin-1 marks myeloid-primed fetal hematopoietic stem cells that undergo progressive lineage-restriction with age

Banuelos, A., Baez, M., Yilmaz, L., Koren-Sedova, E., Zukowska, M., Burden, A. T., Swartzrock-Willner, L., Le, U., Zhang, A., Georgeos, N., Ohene-Gambill, B., Zheng, B., Womack-Gambrel, N., Honjol, R., Sinha, R., Weissman, I. L.

10.64898/2026.09.01.747091 — Posted: 2026-09-03

Rebuilding microbiome diversity theory on the closed simplex

Zhang, Y., Zhu, Z.

10.64898/2026.09.02.748976 — Posted: 2026-09-03

Network and receptor architectures shape brain morphometry in addiction

Georgiadis, F., Milano, B. A., Lariviere, S., Hutchinson, K. E., Calhoun, V., Li, C.-S. R., Momenan, R., Sinha, R., Veltman, D., van Holst, R., Goudriaan, A., Luijten, M., Groefsema, M., Walter, H., Lett, T., Wiers, R., Schmaal, L., Flanagan, J., Porjesz, B., Ipser, J., Boehmer, J., Canessa, N., Salas, R., London, E., Paulus, M., Stein, D., Brooks, S., Reneman, L., Schrantee, A., Filbey, F., Hester, R., Yucel, M., Lorenzetti, V., Solowij, N., Martin-Santos, R., Batalla, A., Cousijn, J., Pomarol-Clotet, E., Garza-Villarreal, E. A., Leyton, M., Stein, E., Crunelle, C. L., Kaag, A. M., Verdejo-Ga

10.64898/2026.04.03.26348150 — Posted: 2026-09-03

Hybrid risk scores integrating polygenic and clinical variables for endometriosis prediction

Goroshchuk, O., Koller, D.

10.64898/2026.08.31.26361798 — Posted: 2026-09-03

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