Channel:  Babraham Institute

154 Articles

Pervanadate-induced oxidation relieves autoinhibition of SRC protein tyrosine kinase
Mulholland, K. E., Bourguet, M., Cheng, N., Rahman, O., Ezerina, D., Daly, L. A., Lai, T., Casanova, S. A., Creixell, P., Eyers, C., Eyers, P., Messens, J., Byrne, D., Sharpe, H.
10.1101/2025.04.27.650842 — Posted: 2025-04-27
Re-engineering of acetyl coenzyme A metabolism prevents senescence in budding yeast
Hadj-Moussa, H., Ulusan, M., Horkai, D., Mirza, M. K. A., Houseley, J.
10.1101/2025.03.27.645766 — Posted: 2025-03-27
RNA helicase DDX1 regulates germinal centre selection and affinity maturation by promoting tRNA ligase activity
Kimber, R., Ingelsfield, S., Screen, M., Salerno, F., Matheson, L. S., Okkenhaug, H., Whale, A., Assalaarachchi, J., Stammers, M., Akdeniz, D., Andrews, S., Ribeiro de Almeida, C.
10.1101/2025.01.10.632317 — Posted: 2025-01-14
RNA-binding proteins control the G2-M checkpoint of the germinal centre B cell
Salerno, F., Whale, A., Matheson, L. S., Foster, W., Stammers, M., Bell, S. E., Hidson, D. J., Linterman, M. A., Houseley, J. A., Turner, M.
10.1101/2024.12.01.626220 — Posted: 2024-12-05
p110alpha-dependent hepatocyte signaling is critical for liver gene expression and its rewiring in MASLD
Regnier, M., Polizzi, A., Fougeray, T., Fougerat, A., Perrier, P., Anderson, K., Lippi, Y., Smati, S., Lukowicz, C., Lasserre, F., Fouche, E., Huillet, M., Rives, C., Tramunt, B., Naylies, C., Garcia, G., Rousseau-Bacquie, E., Bertrand-Michel, J., Canlet, C., Chevolleau-Mege, S., Debrauwer, L., Heymes, C., Burcelin, R., Levade, T., Gourdy, P., Wahli, W., Blum, Y., Gamet-Payrastre, L., Ellero-Simatos, S., Guillermet-Guibert, J., Hawkins, P., Stephens, L., Postic, C., Montagner, A., Loiseau, N., Guillou, H.
10.1101/2024.01.09.574858 — Posted: 2024-10-31
KRAS G12 mutant alleles differentially control glutamine metabolism via FOXO1
Ber, S., Yang, M., Sciacovelli, M., Samarajiwa, S., Patel, K., Nikitopoulou, E., Howitt, A., Cook, S. J., Venkitaraman, A. R., Frezza, C., Esposito, A.
10.1101/2024.10.19.618135 — Posted: 2024-10-22
A distinctive PI(4,5)P2 compartment forms during entosis and related engulfment processes
Durgan, J., Sloan, K., Domart, M.-C., Collinson, L., Florey, O.
10.1101/2024.10.22.619613 — Posted: 2024-10-22
The consequences of mismatched buffers in spectral cell sorting
Dapaah, R. A. S., Ferrer Font, L., Shi, X., Hall, C., Thompson, S., Catharina Costa, L., Mage, P. L., Tyznik, A. J., Lundsten, K., Walker, R. V.
10.1101/2024.08.19.608560 — Posted: 2024-08-19
Eomes directs the formation of spatially and functionally diverse extra-embryonic hematovascular tissues
Theeuwes, B., Harland, L. T., Bisia, A., Costello, I., Ton, M.-L., Lohoff, T., Clark, S. J., Argelaguet, R., Wilson, N. K., Reik, W., Bikoff, E., Robertson, E. J., Gottgens, B.
10.1101/2024.08.13.607790 — Posted: 2024-08-16
RAF inhibitors activate the integrated stress response by direct activation of GCN2
Gilley, R., Kidger, A. M., Neill, G., Severson, P., Byrne, D. P., Kenneth, N. S., Bollag, G., Zhang, C., de Oliveira, T. M., Eyers, P., Bayliss, R., Masson, G. R., Cook, S. J.
10.1101/2024.08.15.607884 — Posted: 2024-08-16

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