Channel:  The Howard Hughes Medical Institute (HHMI)

2,454 Articles

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Enhancer buffering protects dosage-sensitive housekeeping genes during vulnerable developmental transitions
Ni, C., Ichino, L., Swigut, T., Wysocka, J.
10.64898/2026.07.29.741571 — Posted: 2026-07-30
Activity-driven proprioceptive synaptic refinement in the developing spinal cord by complement signaling mechanisms
Nagaraja, C., Ortiz, S., Murali, A. R., Sarwar, A., Griffith, T. N.
10.1101/2025.08.22.671861 — Posted: 2026-07-30
Spatial gene expression maps in vertebrate limbs display conserved and regenerative species-specific features within connective tissue
McMann, C. L., Park, C., Cloutier, J. K., Reddien, P.
10.64898/2025.12.15.694399 — Posted: 2026-07-29
Computational design of metalloproteases
Chen, A., Wu, K., Choi, H., Venkatesh, P., Pellock, S. J., Hanikel, N., Shin, H., Evans, D., Didi, K., Schaaf, L. L., Diaz-Perlas, C., Coventry, B., Kim, D., Woodbury, S. M., Ji, P., Honda, S., Bera, A., Nguyen, H., Kang, A., Wang, Y., Li, X., Gerben, S., Chang, L., Yan, X., Oller-Salvia, B., Hyman, A. A., Hilvert, D., Baker, D.
10.1101/2025.11.20.689622 — Posted: 2026-07-29
Naegleria amoebae seek confinement and crawl persistently through narrow spaces
Velle, K., Ramaswamy, M., Hokmabad, B. V., Martin-Perez, T., Carrasco, T. T., Callahan, W. S., Kim, H. S., Larkin, E. M., ElZafarany, A. H., Jacques, S. M., Datta, S. S., Edwards, M., Fritz-Laylin, L.
10.1101/2025.11.30.691445 — Posted: 2026-07-29
Molecular basis for chikungunya virus recognition of a mosquito-specific receptor
Fan, X., Li, W., Plung, J. S., Plante, J. A., Hajovsky, E. M., Tapryal, N., Diaz, J., Hazell, N. C., Ji, C., Liu, Z., Hammond, C. E., Weaver, S. C., Plante, K. S., Abraham, J.
10.64898/2026.07.28.741352 — Posted: 2026-07-29
Identifying endogenous substrates of the 26S proteasome through site-specific photocrosslinking
Yori Restrepo, S., Martin, A.
10.64898/2026.07.19.739412 — Posted: 2026-07-29
A minimal kinase-phosphatase system and its lipid substrates self-organize into dynamic patterns
Hsieh, T.-S., Ramm, B., Yu, Q., Yuly, J. L., Pfister, J., Wu, Y., Huang, J., Meir, Y., Wingreen, N. S., Tagliabracci, V. S.
10.64898/2026.07.27.740984 — Posted: 2026-07-29
Nocturnin drives mitochondrial NADP(H)/NAD(H) rhythms to regulate steroid rhythm amplitude and time metabolism
Palluth, L., Laothamatas, I., Nguyen, T.-N., Rasmussen, E. S., Zacharias, L. G., Velasquez, M. J., Inigo-Vollmer, M., Fu, X., Mathews, T. P., McDonald, J. G., Burgess, S. C., Takahashi, J. S., Green, C. B.
10.64898/2026.07.24.740574 — Posted: 2026-07-28
Lachesin is a mosquito receptor for multiple arthritogenic alphaviruses
Plung, J. S., Mameli, E., Li, W., de Bruin, A. C. M., Plante, J. A., Fan, X., Das, B., Willett, B. C., Hu, Y., Hajovsky, E. M., Varnum, H., Anekal, P. V., Sun, X., Thornburg, K., Brusic, V., Hammond, C. E., Montero Llopis, P., Viswanatha, R., Shaw, W. R., Catteruccia, F., Weaver, S. C., Plante, K. S., Perrimon, N., Abraham, J.
10.64898/2026.07.28.741058 — Posted: 2026-07-28

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