Channel:  The Howard Hughes Medical Institute (HHMI)

2,006 Articles

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Machine learning-guided spatial omics for tissue-scale discovery of cell-type-specific architectures
Lian, Y., Adjavon, D., Kawase, T., Kim, J., Fleishman, G., Preibisch, S., Funke, J., Liu, Z. J.
10.64898/2026.02.12.705598 — Posted: 2026-02-13
4,5-dihydroxyhexanoic acid is a robust circulating and urine marker of mitochondrial disease and its severity
Skinner, O. S., Miranda, M., Dong, F., Struhl, T., Walker, M. A., Schleifer, G., Henke, M. T., Clardy, J., Hirano, M., De Vivo, D. C., Schon, E. A., Engelstad, K., Siegmund, S. E., Laprise, C., Des Rosiers, C., Sharma, R., Mootha, V. K.
10.64898/2026.02.10.705117 — Posted: 2026-02-12
Evidence for non-optimal codon choice in highly transcribed sex-biased genes of Drosophila melanogaster
Whittle, C. A., Extavour, C. G.
10.1101/2024.11.24.625100 — Posted: 2026-02-12
Chromatin boundary permeability is controlled by CTCF conformational ensembles
Rudnizky, S., Murray, P. J., Sorensen, E. W., Koenig, T. J. R., Pangeni, S., Merino-Urteaga, R., Chhabra, H., Caccianini, L., Davidson, I. F., Osorio-Valeriano, M., Hook, P. W., Meneses, P., Hao, J., Zarb, J. S., Hatzakis, N. S., Timp, W., Farnung, L., Vos, S. M., Peters, J.-M., Aksimentiev, A., Ha, T.
10.1101/2025.11.25.690553 — Posted: 2026-02-12
The dynamic evolution of panarthropod germ cell specification mechanisms
Kao, J. A., Rivard, E. L., Kapoor, R. R., Extavour, C. G.
10.1101/2025.08.05.668520 — Posted: 2026-02-12
Tissue-specific regulation of PNPLA3 promotes lipid remodeling in response to dietary and environmental challenges
Wu, P., Wang, Y., Cohen, J. C., Hobbs, H. H.
10.1101/2025.10.27.684800 — Posted: 2026-02-11
A System for Live Sorting of Neuronal Spiking Activity from Large-scale Recordings
Muralidharan, S., Leng, C., Orts, L., Trepka, E., Zhu, S., Panichello, M., Jonikaitis, D., Pennington, J., Pachitariu, M., Moore, T.
10.64898/2025.12.29.696938 — Posted: 2026-02-11
A plasma-based DNA test for quantification of disease burden in acute myeloid leukemia patients undergoing bone marrow transplantation
Wang, Y., Xie, J., Pasca, S., Popoli, M., Ptak, J., Dobbyn, L., Silliman, N., Paul, S., Jones, R. J., Levis, M. J., Curtis, S. D., Douville, C., Shams, C., Guo, M. Z., Mo, S., Gocke, C. D., Malek, S. N., Bollard, C. M., Bettegowda, C., Kinzler, K. W., Vogelstein, B., Papadopoulos, N., Gondek, L. P.
10.64898/2026.02.10.26345949 — Posted: 2026-02-11
A pilot study for whole proteome tagging in C. elegans
Eroglu, M., Hobert, O.
10.64898/2026.02.09.704846 — Posted: 2026-02-10
Multiple redundant mechanisms account for the majority of gene silencing downstream of DNA methylation
Wang, S., Wu, Z., Li, Z., Movilli, A., He, L., Zhou, Y., Lin, E. K., Chuang, R., Thiri, W. W., Convery, S., Feng, S., Weigel, D., Jacobsen, S. E.
10.64898/2026.02.08.704674 — Posted: 2026-02-10

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