Channel:  The Howard Hughes Medical Institute (HHMI)

2,006 Articles

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In extracto cryo-EM reveals eEF2 as a major hibernation factor on 60S and 80S particles
Seraj, Z., Zottig, X., Huang, C., Loveland, A. B., Diggs, S., Sholi, E., Grigorieff, N., Korostelev, A. A.
10.1101/2025.11.25.690450 — Posted: 2026-03-17
A widespread electrical brain network encodes anxiety in health and depressive states
Hughes, D. N., Klein, M. H., Walder-Christensen, K. K., Thomas, G. E., Grossman, Y., Waters, D., Matthews, A. E., Carson, W. E., Filali, Y., Tsyglakova, M., Fink, A., Gallagher, N. M., Perez-Balaguer, M., McClung, C. A., Zarate, J. M., Hultman, R. C., Mague, S. D., Carlson, D., Dzirasa, K.
10.1101/2024.06.26.600900 — Posted: 2026-03-17
The Drosophila ovary produces two waves of adult follicles and a novel pupal wave that turns over
Fu, W. Y., Spradling, A. C.
10.1101/2025.11.11.687893 — Posted: 2026-03-16
Meta-learning is expressed through altered prefrontal cortical dynamics
Sun, X., Comrie, A. E., Kahn, A. E., Monroe, E. J., Washington, C. B., Joshi, A., Guidera, J. A., Denovellis, E. L., Krausz, T. A., Zhou, J., Thompson, P., Hernandez, J., Yorita, A., Haque, R., Pandarinath, C., Berke, J. D., Daw, N. D., Frank, L. M.
10.64898/2026.01.01.697272 — Posted: 2026-03-16
Expression of four mitochondrial tRNAs from only two loci
Warren, J. M., Prasad, K. V. S. K., Mendez, A. M., Temnyk, S., McCutcheon, J.
10.1101/2025.11.12.688142 — Posted: 2026-03-14
Genomic surveillance reveals age-structured SARS-CoV-2 transmission across demographics and settings
Moreno, G. K., Brock-Fisher, T., Krasilnikova, L. A., Schaffner, S., Burns, M., Casiello, C. E., Messer, K. S., Petros, B. A., Specht, I., DeRuff, K. C., Siddle, K. J., Loreth, C., Fitzgerald, N. A., Rooke, H. M., Gabriel, S. B., Smole, S., Wohl, S., Park, D. J., Madoff, L. C., Brown, C. M., MacInnis, B. L., Sabeti, P. C.
10.1101/2025.04.04.25324273 — Posted: 2026-03-13
Antibody Mediated Diversification of Primary and Secondary Humoral Immune Responses
Schaefer-Babajew, D., Binet, L., Santos, G. S. S., Ruprecht, C., Deimel, L. P., ElTanbouly, M. A., Gharrassi, D., Lima dos Reis, G., Uhe, C., Yao, K.-H., Hernandez, B., Agrawal, P., Gazumyan, A., Stamatatos, L., Hartweger, H., Nussenzweig, M. C.
10.64898/2025.12.15.694384 — Posted: 2026-03-13
Enhancer binding kinetics explain transcription factor hub formation
Fallacaro, S., Kapoor, M., Encarnation, L., Mukherjee, A., Turner, M. A., Garcia, H. G., Mir, M.
10.1101/2025.04.07.647578 — Posted: 2026-03-12
Lipid metabolism of hepatocyte-like cells supports intestinal tumor growth in Drosophila
Huang, K., Miao, T., Sanford, J., Chen, Y., Moon, S. J., Dantas, E., Han, M., Hu, Y., Wang, K., Goncalves, M., Perrimon, N.
10.1101/2025.04.04.647255 — Posted: 2026-03-12
Somatic mosaicism in amyotrophic lateral sclerosis and frontotemporal dementia identifies focal mutations associated with widespread degeneration
Zhou, Z., Kim, J., Huang, A. Y., Nolan, M., Park, J., Doan, R., Shin, T., Miller, M. B., Bae, M., Zhao, B., Kim, J., Chhouk, B., Morillo, K., Yeh, R. C., Kenny, C., Neil, J. E., Lee, C.-Z., Ohkubo, T., Ravits, J., Ansorge, O., Ostrow, L. W., Lagier-Tourenne, C., Lee, E. A., Walsh, C. A.
10.1101/2023.11.30.569436 — Posted: 2026-03-12

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