Channel:  The Howard Hughes Medical Institute (HHMI)

2,105 Articles

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Structural dynamics between Argonaute-2 and CK1α promote target RNA release in microRNA-mediated silencing
Garg, A., Braviner, L., Axhemi, A., Bibel, B., Joshua-Tor, L.
10.64898/2026.03.23.713669 — Posted: 2026-03-25
Discovery of a primed endothelial progenitor that requires VEGF/ERK inhibition to complete vein differentiation
Ang, L. T., Zheng, S. L., Liu, K. J., Masaltseva, A., Winters, J., Jha, S. K., Yin, Q., Qian, C., Xiong, X., Dailamy, A., Xi, E., Alcocer, J. C., Sorensen, D. W., She, R., Smolyar, K., Szumska, D., Nornes, S., Martin, R. M., Lesch, B. J., Restrepo, N. K., Sun, W., Weissman, J. S., Lickert, H., Porteus, M. H., Skylar-Scott, M. A., Mosimann, C., Sumanas, S., De Val, S., Red-Horse, K., Loh, K. M.
10.1101/2025.10.11.681838 — Posted: 2026-03-25
Subsistence transition preceded population turnover in the eastern Colombian Andes
Sirak, K., Delgado, M., Triana, A., Rivas, S., Argüello, P., Boada, A. M., Rivera-Sandoval, J., Pena, G., Langebaek, C., Ospina, J. P., Archila, S., Torres Orjuela, S. A., Mejia Cano, M. B., Rodriguez Saza, F., Barton, A., Callan, K., Curtis, E., Frost, T., Iliev, L., Kearns, A., Kellogg, J., Lawson, A. M., Qiu, L., Workman, J. N., Mah, M., Nawaz, M., Soos, G., Cherkinsky, A., Hadden, C. S., Prufer, K. M., Mallick, S., Rohland, N., Fehren-Schmitz, L., Reich, D.
10.64898/2026.03.23.713713 — Posted: 2026-03-25
Bacteriophages target membrane-anchored glycopolymers to promote host cell lysis and progeny release
McKitterick, A. C., Lyerly, E. W., Bernhardt, T. G.
10.1101/2025.06.24.661397 — Posted: 2026-03-25
Paleogenomic Evidence for Genetic Heterogeneity and Prior Admixture in Gothic-Associated Communities of Late Antique Bulgaria
Stamov, S., Chobanov, T., Wang, T., Stoeva, K., Momchilov, D., Aladzhov, A., Chobanov, K., Nikolov, M., Nesheva, D., Heather, P., Toncheva, D. I., Zamfirov, M., Lazaridis, I., Reich, D. E., Klasnakov, M., Stamov, G.
10.64898/2026.03.03.709317 — Posted: 2026-03-25
HIV-1 infection does not confer intrinsic resistance to cell death induced by cytotoxic T lymphocytes
Bachmann, N., Kim, B., Simonetti, F. R., Kovacs, C. M., Hoh, R., Deeks, S. G., Siliciano, J. D., Siliciano, R. F.
10.64898/2026.03.23.713717 — Posted: 2026-03-25
FoTO1 orchestrates Taxol biosynthesis through catalytic and non-catalytic mechanisms
Wick, C., Somani, A., Liu, J., Karunadasa, S. S., Xu, S.-L., Fordyce, P. M., McClune, C. J., Sattely, E.
10.64898/2026.03.21.713420 — Posted: 2026-03-24
Inter-individual variation of cellular and gene-expression properties of the human striatum
Burger, S., Yoo, O., Nemesh, J., Muratoglu, E., Vanderburg, C., Yuan, J., Shakir, K., Mello, C. J., Rayan, N. A., Milidantri, J., Kim, K., Drouin, S., Finn, E., Gao, H., Budnik, N., Goldman, M., Fritch, H., Genovese, G., Hogan, M., Catalini, O., Kashin, S., Rockweiler, N., Wysoker, A., Macaisa, L., Reese, L., Flowers, K., Kraft, A. W., Fleming, S. J., Coe, M., Gunaratne, R., Spina, L., Crombie, C., Mohsin, A., Kamitaki, N., Macosko, E. Z., Ichihara, K., McCarroll, S. A.
10.64898/2026.03.20.713160 — Posted: 2026-03-23
Transcriptomic and functional characterization indicate sexual dimorphism of discrete circadian neuron subtypes
Perez Torres, M., Jiang, R., Ma, D., Herndon, N., Kurmangaliyev, Y. Z., Guo, F., Rosbash, M.
10.64898/2025.12.26.696620 — Posted: 2026-03-23
Mechanism and Structure-Guided Optimization of SLC1A1/EAAT3-Selective Inhibitors in Kidney Cancer
Koochaki, P., Qiu, B., Coker, J. A., Earsley, A., Wang, N. S., Romigh, T., Goins, C. M., Salem, C., Mi, D., Days, E., Bauer, J., Stauffer, S. R., Boudker, O., Chakraborty, A. A.
10.1101/2025.07.03.663021 — Posted: 2026-03-19

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