Channel:  The Howard Hughes Medical Institute (HHMI)

2,106 Articles

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Homozygosity for rare or common hypomorphic IL23R variants confers a predisposition to tuberculosis in humans
Olguin Calderon, D., Kilpatrick, L. E., Conil, C., Philippot, Q., Ogishi, M., Vellutini, J., Eun Han, J., Keating, N., Li, H., Rao, G., Bohlen, J., Lay, C. S., Platt, S., Kerner, G., Feredj, E., Peel, J., Momenilandi, M., Seeleuthner, Y., Laine, C., soudee, c., Leloup, C., Debuisson, C., Lanternier, F., Bitoun, S. B., Pavy, S., Mariette, X., Rafik, A., Skhoun, H., EL Ouazzani, H., Abderahmani-Ghorfi, I., EL Baghdadi, J., Baena, A., Tejada-Giraldo, M., Barrera, L. F., Arias, A. A., Fabio, G., Carrabba, M., Emiroglu, M., Bezrodnik, L., EL Zein, L., Hammoud, H., Gregersen, P., Terrier, B., Leon L
10.64898/2026.03.23.713554 — Posted: 2026-03-25
Structural dynamics between Argonaute-2 and CK1α promote target RNA release in microRNA-mediated silencing
Garg, A., Braviner, L., Axhemi, A., Bibel, B., Joshua-Tor, L.
10.64898/2026.03.23.713669 — Posted: 2026-03-25
Subsistence transition preceded population turnover in the eastern Colombian Andes
Sirak, K., Delgado, M., Triana, A., Rivas, S., Argüello, P., Boada, A. M., Rivera-Sandoval, J., Pena, G., Langebaek, C., Ospina, J. P., Archila, S., Torres Orjuela, S. A., Mejia Cano, M. B., Rodriguez Saza, F., Barton, A., Callan, K., Curtis, E., Frost, T., Iliev, L., Kearns, A., Kellogg, J., Lawson, A. M., Qiu, L., Workman, J. N., Mah, M., Nawaz, M., Soos, G., Cherkinsky, A., Hadden, C. S., Prufer, K. M., Mallick, S., Rohland, N., Fehren-Schmitz, L., Reich, D.
10.64898/2026.03.23.713713 — Posted: 2026-03-25
Progressive hypothalamic neuroinflammation after ovariectomy in mice parallels age-related transcriptomic changes in the female human hypothalamus
Bloom, J. C. B., Torres, E., Pereira, S. A., Arvizu-Sanchez, L., Fontes, A. N., Joffe, H., Page, D. C., Navarro, V. M.
10.1101/2024.10.05.616758 — Posted: 2026-03-25
Paleogenomic Evidence for Genetic Heterogeneity and Prior Admixture in Gothic-Associated Communities of Late Antique Bulgaria
Stamov, S., Chobanov, T., Wang, T., Stoeva, K., Momchilov, D., Aladzhov, A., Chobanov, K., Nikolov, M., Nesheva, D., Heather, P., Toncheva, D. I., Zamfirov, M., Lazaridis, I., Reich, D. E., Klasnakov, M., Stamov, G.
10.64898/2026.03.03.709317 — Posted: 2026-03-25
Discovery of a primed endothelial progenitor that requires VEGF/ERK inhibition to complete vein differentiation
Ang, L. T., Zheng, S. L., Liu, K. J., Masaltseva, A., Winters, J., Jha, S. K., Yin, Q., Qian, C., Xiong, X., Dailamy, A., Xi, E., Alcocer, J. C., Sorensen, D. W., She, R., Smolyar, K., Szumska, D., Nornes, S., Martin, R. M., Lesch, B. J., Restrepo, N. K., Sun, W., Weissman, J. S., Lickert, H., Porteus, M. H., Skylar-Scott, M. A., Mosimann, C., Sumanas, S., De Val, S., Red-Horse, K., Loh, K. M.
10.1101/2025.10.11.681838 — Posted: 2026-03-25
HIV-1 infection does not confer intrinsic resistance to cell death induced by cytotoxic T lymphocytes
Bachmann, N., Kim, B., Simonetti, F. R., Kovacs, C. M., Hoh, R., Deeks, S. G., Siliciano, J. D., Siliciano, R. F.
10.64898/2026.03.23.713717 — Posted: 2026-03-25
FoTO1 orchestrates Taxol biosynthesis through catalytic and non-catalytic mechanisms
Wick, C., Somani, A., Liu, J., Karunadasa, S. S., Xu, S.-L., Fordyce, P. M., McClune, C. J., Sattely, E.
10.64898/2026.03.21.713420 — Posted: 2026-03-24
Inter-individual variation of cellular and gene-expression properties of the human striatum
Burger, S., Yoo, O., Nemesh, J., Muratoglu, E., Vanderburg, C., Yuan, J., Shakir, K., Mello, C. J., Rayan, N. A., Milidantri, J., Kim, K., Drouin, S., Finn, E., Gao, H., Budnik, N., Goldman, M., Fritch, H., Genovese, G., Hogan, M., Catalini, O., Kashin, S., Rockweiler, N., Wysoker, A., Macaisa, L., Reese, L., Flowers, K., Kraft, A. W., Fleming, S. J., Coe, M., Gunaratne, R., Spina, L., Crombie, C., Mohsin, A., Kamitaki, N., Macosko, E. Z., Ichihara, K., McCarroll, S. A.
10.64898/2026.03.20.713160 — Posted: 2026-03-23
Transcriptomic and functional characterization indicate sexual dimorphism of discrete circadian neuron subtypes
Perez Torres, M., Jiang, R., Ma, D., Herndon, N., Kurmangaliyev, Y. Z., Guo, F., Rosbash, M.
10.64898/2025.12.26.696620 — Posted: 2026-03-23

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