Channel:  The Howard Hughes Medical Institute (HHMI)

2,121 Articles

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The Drosophila ovary produces two waves of adult follicles and a novel pupal wave that turns over
Fu, W. Y., Spradling, A. C.
10.1101/2025.11.11.687893 — Posted: 2026-03-18
Rapid and repeated evolution of myosin copy number in threespine stickleback
Yoxsimer, A. M., Daugherty, R. R., Hare, E. E., Chan, Y. F., Jones, F. C., Roberts Kingman, G. A., Offenberg, E. G., Howes, T. R., Zhang, H., Pollen, A. A., Brady, S. D., Xie, K. T., Chen, H. I., Lowe, C. B., Au, E. H., Grimwood, J., Schmutz, J., Myers, R. M., Schluter, D., Heins, D. C., Reyes, M. L., Baker, J. A., Jonsson, B., Reimchen, T. E., Bell, M. A., Kingsley, D. M.
10.64898/2025.12.22.696110 — Posted: 2026-03-17
Biophysical trade-offs in antibody evolution are resolved by conformation-mediated epistasis
Tharp, C. R., Catalano, C., Khalifeh, A., Ghaffari-Kashani, S., Huang, R., Kang, G., Scapin, G., Phillips, A. M.
10.64898/2026.03.12.711465 — Posted: 2026-03-17
In vivo multiomic Perturb-seq with enhanced nuclear gRNA capture
Zheng, X., Li, J., Kim, K., Simmons, S. K., Zhao, Z., Tastemel, M., Huynh, N., Qiu, H., Ye, J., Whte, C. M., Levin, J. Z., Jin, X.
10.64898/2026.03.15.711739 — Posted: 2026-03-17
A widespread electrical brain network encodes anxiety in health and depressive states
Hughes, D. N., Klein, M. H., Walder-Christensen, K. K., Thomas, G. E., Grossman, Y., Waters, D., Matthews, A. E., Carson, W. E., Filali, Y., Tsyglakova, M., Fink, A., Gallagher, N. M., Perez-Balaguer, M., McClung, C. A., Zarate, J. M., Hultman, R. C., Mague, S. D., Carlson, D., Dzirasa, K.
10.1101/2024.06.26.600900 — Posted: 2026-03-17
In extracto cryo-EM reveals eEF2 as a major hibernation factor on 60S and 80S particles
Seraj, Z., Zottig, X., Huang, C., Loveland, A. B., Diggs, S., Sholi, E., Grigorieff, N., Korostelev, A. A.
10.1101/2025.11.25.690450 — Posted: 2026-03-17
Statistical BURST imaging for high-fidelity biomolecular ultrasound
Lee, S., Shivaei, S., Shapiro, M. G.
10.64898/2026.03.13.711726 — Posted: 2026-03-17
Meta-learning is expressed through altered prefrontal cortical dynamics
Sun, X., Comrie, A. E., Kahn, A. E., Monroe, E. J., Washington, C. B., Joshi, A., Guidera, J. A., Denovellis, E. L., Krausz, T. A., Zhou, J., Thompson, P., Hernandez, J., Yorita, A., Haque, R., Pandarinath, C., Berke, J. D., Daw, N. D., Frank, L. M.
10.64898/2026.01.01.697272 — Posted: 2026-03-16
Specialization of independently acquired flagellar FliC proteins in plant-associated Sphingomonas balances swimming and immunogenicity
Russ, D., Saha, C., Paul, K., Zheng, Z., Law, T. F., Anguita-Maeso, M., Lundberg, D. S., Fitzpatrick, C. R., Dangl, J. L.
10.64898/2026.02.23.707200 — Posted: 2026-03-16
A stress-function tradeoff organizes epithelial heterogeneity across spatial scales in the human thyroid
Korem Kohanim, Y., Barkai, T., Novoselsky, R., Shir, S., Bahar Halpern, K., Reich-Zeliger, S., Elkahal, J., Tessler, I., Shivatzki, S., Schwartz, I., Remer, E., Avior, G., Hoefllin, R., Kedmi, M., Keren-Shaul, H., Goliand, I., Addadi, Y., Golani, O., Alon, E., Itzkovitz, S., Medzhitov, R.
10.64898/2026.03.12.711294 — Posted: 2026-03-16

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