Channel:  The Howard Hughes Medical Institute (HHMI)

1,285 Articles

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Temperate phages enhance host fitness via RNA-guided flagellar remodeling
Walker, M. W. G., Richard, E., Wiegand, T., Wang, J., Yang, Z., Casas-Ciniglio, A. A., Hoffmann, F. T., Shahnawaz, H., Gaudet, R. G., Arpaia, N., Fernandez, I. S., Sternberg, S. H.
10.1101/2025.07.22.666180 — Posted: 2025-07-22
Chromosome scale genomes of two invasive Adelges species enablevirtual screening for selective adelgicides
Glendening, A. M., Stephens, C., Vuruputoor, V. S., Chaganti, T., Myles, M., Stern, D. L., Abdelalim, M., Juang, Y.-P., Hogenhout, S. A., Mathers, T. C., Pauloski, N., Cernak, T. A., Wegrzyn, J. L., Fetter, K. C.
10.1101/2024.11.21.624573 — Posted: 2025-07-22
Mouse pups lacking a cerebral cortex develop abnormal vocal behavior
Boyd, J. L., Vargas, C., Jarvis, E. D.
10.1101/2025.07.17.665371 — Posted: 2025-07-22
Long-read sequencing of trios reveals increased germline and postzygotic mutation rates in repetitive DNA
Noyes, M. D., Sui, Y., Kwon, Y., Koundinya, N., Wong, I., Munson, K. M., Hoekzema, K., Kordosky, J., Garcia, G. H., Knuth, J., Lewis, A. P., Eichler, E. E.
10.1101/2025.07.18.665621 — Posted: 2025-07-19
Neuroligin-3 interaction with CSPG4 regulates normal and malignant glial precursors through PIEZO1
Gillespie, S. M., Kim, Y. S., Geraghty, A. C., Yalcin, B., Mancusi, R., Hysinger, J., Ivec, A. E., Reed, J., Drexler, R., Quezada, M., Malacon, K., Woo, P. J., Yang, A., Lam, M., Pan, Y., Zuchero, J. B., Trotter, J., Monje, M.
10.1101/2025.07.12.664340 — Posted: 2025-07-17
miRNA circuit modules for precise, tunable control of gene expression
Du, R., Flynn, M. J., Mahe, K., Honsa, M., Gu, B., Li, D., McGeary, S. E., Gradinaru, V., Jungmann, R., Elowitz, M. B.
10.1101/2024.03.12.583048 — Posted: 2025-07-16
Programmable translational inhibition by a molecular glue-oligonucleotide conjugate
Wang, S., Kovalski, J. R., Zapatero-Belinchon, F. J., Bennett, M., Kuzuoglu-Öztürk, D., Li, Q., Stevenson, E., Liu, J., Krogan, N. J., Ott, M., Swaney, D. L., Ruggero, D., Lou, K., Shokat, K.
10.1101/2025.07.15.664547 — Posted: 2025-07-16
Genetic variation reveals a homeotic long noncoding RNA that modulates human hematopoietic stem cells
Lyu, P., Agarwal, G., Guo, C.-J., Ye, T., Weng, C., Antoszewski, M., Joubran, S., Caulier, A., Poeschla, M., Sankaran, V. G.
10.1101/2025.07.16.664824 — Posted: 2025-07-16
Complete chromosome 21 centromere sequencing of families with Down syndrome reveals centromere size asymmetry
Mastrorosa, F. K., Daponte, A., Wertz, J., Rozanski, A. N., Harvey, W. T., Porubsky, D., Knuth, J., Garcia, G., Ayllon, M., Munson, K. M., Hoekzema, K., He, W., Sherman, S. L., Allen, E. G., Rosser, T. C., Catacchio, C. R., Ventura, M., Logsdon, G. A., Eichler, E. E.
10.1101/2024.02.25.581464 — Posted: 2025-07-16
AAV NRF2 Gene Therapy Preserves Retinal Structure and Function in Rodent Models of Oxidative Damage
Gardner, A., Wang, S., Daniels, A., Li, D., Wu, C., Lin, L., Hong, C., Zhao, S., Kruczek, K., Weist, G., Real, L. B., Haurigot, V., Born, R., Cepko, C.
10.1101/2025.07.09.663952 — Posted: 2025-07-14

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