Channel:  The Howard Hughes Medical Institute (HHMI)

2,390 Articles

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Gut-derived serine protease reduces sleep but extends lifespan
Moore, R. S., Xiong, R., Astacio, E., Williams, J. A., Brooks, T., Grant, G., Stucynski, J., Fazelinia, H., Nash, E., Spruce, L., Sehgal, A.
10.64898/2026.06.25.734557 — Posted: 2026-06-29
Mechanism of tandem-repeat DNA synthesis by an antiviral reverse transcriptase
Ramirez, J. L., He, Q., Wiegand, T., Lampe, G., Wang, J., Tang, S., Fernandez, I. S., Sternberg, S. H.
10.64898/2026.06.29.735271 — Posted: 2026-06-29
Dystrophic changes of nigrostriatal axons harboring a Synj1 Parkinson mutation suggest catastrophic failure of endocytic mechanisms
Wu, Y., Xu, P., Moran, J., Xu, C. S., Hayworth, K., Cao, M., Shao, L., Surmeier, D. J., Hess, H., De Camilli, P.
10.64898/2026.06.24.733515 — Posted: 2026-06-29
High risk of hypoxemic COVID-19 pneumonia in myasthenia gravis patients with type I IFN autoantibodies
Gervais, A., Marchal, A., Maillard, A., Le Voyer, T., Rosain, J., Philipot, Q., Bizien, L., Peel, J., Cederholm, A., Migaud, M., Pons, S., Saker, K., Laforet, P., Aubart, M., Gitiaux, C., Biggs, C., Leon Lopez, R., Souvannanorath, S., Tard, C., Nadaj Pakleza, A., Grapperon, A.-M., Heming, N., Annane, D., Verschueren, A., Attarian, S., Bigaut, K., Hankiewicz, K., Kouton, L., Villar-Quiles, R.-N., Cauquil, C., Fleury, M.-C., Rocher, E., Nicolas, G., de Paula Estephan, E., da Penha Ananias Morita, M., Zanoteli, E., Saied, Z., Rachdi, A., Rim, A., Belal, S., Ben Sassi, S., Hubers, A., Faure, E., D
10.64898/2026.03.27.26349525 — Posted: 2026-06-29
The genomic origins and evolutionary path to a key innovation in the world's most venomous snakes
van Thiel, J., Dowell, N., Smith, C. F., Sanchez, E. E., Carroll, S.
10.64898/2026.06.23.733212 — Posted: 2026-06-28
Maternal experience alters brain-wide representation of infant cries
McRae, B. R., Ferguson, D.-L. K. D., Swanier, K., Allen, G. I., Marlin, B. J.
10.64898/2026.06.26.734581 — Posted: 2026-06-28
Peri-Locus Coeruleus Controls Endothelial Cell Heterogeneity in Enriched Environments via Region-Specific Norepinephrine Signaling
Zhao, Y., Li, B., Ju, F., Feng, J., Wei, J.-a., Shao, J., Sun, W., Chen, S., Qiu, Y., Gao, D., Zhang, L., Chen, Y., Li, Y., Wang, L., Tu, J., Yang, F.
10.64898/2026.06.23.733358 — Posted: 2026-06-28
The type VI secretion system governs strain maintenance in a wild mammalian gut microbiome
Shen, B. A., Asfahl, K. L., Lim, B., Bertolli, S. K., Minot, S. S., Radey, M. C., Penewit, K., Ngo, B., Salipante, S. J., Johnston, C. D., Peterson, S. B., Goodman, A. L., Mougous, J. D.
10.1101/2025.11.29.690828 — Posted: 2026-06-26
Development of GS-441524 Derivatives as Potent SARS-CoV-2 Mac1 Inhibitors via a Direct-to-Biology Approach
Peng, K., Chakraborty, S., Wallace, S. D., Noll, J. C. G., Shang, J., Lu, X., Choi, A., Whittaker, G., Fromme, J. C., Lin, H.
10.64898/2026.06.24.734322 — Posted: 2026-06-25
PARP1 Exhibits an Enzymatically Inactive Chromatin Binding Mode
Fiorenza, A., Anand, M., Luger, K.
10.64898/2026.06.24.734344 — Posted: 2026-06-25

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