Channel:  The Howard Hughes Medical Institute (HHMI)

2,117 Articles

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Structural mechanism of Necrocide 1 activation of human TRPM4 that triggers necrosis by sodium overload
Teixeira-Duarte, C. M., Fu, W., Zeng, W. M., Wang, J., Jiang, X., Zhao, Z., Zhong, Q., Jiang, Y.
10.64898/2026.01.28.702369 — Posted: 2026-04-08
Endogenous nucleophilic scavengers of reactive acyl-species neutralize carbon stress
Lee, M.-K., Kim, S. M., Lee, S., Yang, J. H., Choi, C. R., Miao, T., Kim, J.-S., Perrimon, N., Kang, Y. P., Rhee, H.-W.
10.64898/2026.04.06.716549 — Posted: 2026-04-08
Evaluating the Utility of a Nanoscale Flow Cytometer for Detection of Surface Proteins on HIV and Extracellular Vesicles
Burnie, J., Ouano, C., Costa, V., Castrosin, I., Hammond, C., Matthews, H., Tigges, J., Corbett-Helaire, K. S.
10.64898/2026.03.09.710614 — Posted: 2026-04-08
A High-throughput Fluorescence Polarization Assay for Screening Sirtuin Inhibitors
Peng, K., Chakraborty, S., Lin, H.
10.64898/2026.04.06.716694 — Posted: 2026-04-08
Evolutionary transfer learning enables organism-wide inference of mammalian enhancer landscapes
Qiu, C., Daza, R. M., Welsh, I. C., Patwardhan, R. P., Martin, B. K., Li, T., Yang, S., Kempynck, N., Taylor, M. L., Fulton, O., Le, T.-M., O'Day, D. R., Lalanne, J.-B., Domcke, S., Murray, S. A., Aerts, S., Trapnell, C., Shendure, J.
10.64898/2026.04.07.717039 — Posted: 2026-04-08
Septins regulate cytokinesis and multicellular development in the closest living relatives of animals
Carver, M., King, N.
10.64898/2026.04.05.716596 — Posted: 2026-04-07
Nascent CUT&Tag captures transcription factor binding after chromatin duplication
Wooten, M., Nguyen, K., Takushi, B. N., Ahmad, K., Henikoff, S.
10.1101/2025.10.13.682212 — Posted: 2026-04-07
Image Analysis Tools for Scanning Electron Microscopy
Shtengel, D., Shtengel, G., Xu, C. S., Hess, H. F.
10.64898/2026.03.11.711125 — Posted: 2026-04-06
A previously unappreciated class of metal-dependent bile salt hydrolases from the human gut microbiome
Cui, Z., Meng, C. J., Irwin, S. M., Augustijn, H. E., Papageorgiou, P. P., Nguyen, A. T. P., Yu, R., Aguilar Ramos, M. A., Kulik, H. J., Balskus, E. P.
10.64898/2026.04.05.716592 — Posted: 2026-04-06
Sustained interferon exposure creates a hyper-metastatic subset of melanoma cells
Mannino, M., Wei, T., Moose, D. L., Knight, B., Piskounova, E., Shannon, A., Zhao, Z., Morrison, S. J.
10.64898/2026.04.01.715921 — Posted: 2026-04-05

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