Channel:  The Howard Hughes Medical Institute (HHMI)

1,285 Articles

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Positive Selection Screen for Natural Product β-Catenin Inactivators
Boudreau, M. W., Freire, V. F., Corbett, S. C., Martinez-Fructuoso, L., Kumar, R., Thornburg, C. C., Akee, R. K., Peyser, B. D., Jiang, Q., Splaine, J., Pfaff, J. L., Chandler, B. C., Abeja, D. M., Donovan, K. A., Che, J., Lampson, B. L., Szajner, P., Smith, J. A., Koduri, V., Grkovic, T., OKeefe, B. R., Kaelin, W. G.
10.1101/2025.08.27.671140 — Posted: 2025-08-27
Synthetic Phase Variation for Engineered Microbial Consortia
Kratz, M. F., Murray, R. M., Elowitz, M. B.
10.1101/2025.08.25.672192 — Posted: 2025-08-26
A molecularly defined basalo-prefrontal-thalamic circuit regulates sensory and affective dimensions of pain
Xie, G., Liu, Y., Qi, X., Bhattacherjee, A., Zhang, C., Zhang, Y.
10.1101/2025.08.22.671771 — Posted: 2025-08-26
Nucleation limited assembly and polarized growth of a de novo-designed allosterically modulatable protein filament
Shen, H., Lynch, E. M., Shi, C., Watson, J. L., Liu, Y., Wu, K., Bai, H., Kim, C. J., Sheffler, W., Derivery, E., De Yoreo, J. J., Kollman, J. M., Baker, D.
10.1101/2024.09.20.613980 — Posted: 2025-08-26
Determinants of human versus mosquito cell entry by the Chikungunya virus envelope proteins
Ju, X., Hannon, W. W., Kaszuba, T., Radford, C. E., Larsen, B. B., Nelson, S. S., Nelson, C. A., Baltazar-Perez, I., Zimmerman, O., Fremont, D. H., Diamond, M. S., Bloom, J. D.
10.1101/2025.08.25.672233 — Posted: 2025-08-25
Widespread purine bias in bacterial genes driven by runaway transcription
Dierksheide, K. J., Taggart, J. C., Johnson, G. E., Li, G.-W.
10.1101/2025.08.25.672197 — Posted: 2025-08-25
Augment rice ANNEXIN expression to counter planthopper NlAnnexin-like5 as an anti-virulence strategy against a major crop pest
Zhang, X.-Y., Li, S., Opachaloemphan, C., Zhang, C.-X., Jiang, Y., he, s. y.
10.1101/2025.08.18.670976 — Posted: 2025-08-22
Generalized cell phenotyping for spatial proteomics with language-informed vision models
Wang, X., Dilip, R., Iqbal, A. R., Bussi, Y., Brown, C., Pradhan, E., Jain, Y., Yu, K., Li, S., Abt, M., Borner, K., Keren, L., Yue, Y., Barnowski, R., Van Valen, D. A.
10.1101/2024.11.02.621624 — Posted: 2025-08-22
A transcription factor-sRNA-mediated double-negative feedback loop confers pathogen-specific control of quorum-sensing genes
Mashruwala, A. A., Decker, K., Fei, C., Valastyan, J. S., Bassler, B.
10.1101/2025.08.22.671807 — Posted: 2025-08-22
Strain variation identifies a neural substrate for behavioral evolution in Drosophila
Ryba, A., Brand, P., Coleman, R. T., Greenfeld, Y., Tsitohay, Y. N., Hollunder, F., Keller, K., Hathiyari, M., Wei, T., Barbano, P. E., Ruta, V.
10.1101/2025.08.15.670615 — Posted: 2025-08-22

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