Channel:  The Howard Hughes Medical Institute (HHMI)

2,229 Articles

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Structure and Mechanism of a Two-component Lanthipeptide Toxin
Moreira, R., Giurgiu, C., Rahman, I. R., Patterson, M., Huber, S. T., Yang, Y., Jeanne Dit Fouque, K., Fernandez-Lima, F., Liu, G., Guo, R., Kelich, P., Wen, P.-C., Tajkhorshid, E., Johnson, A. G., van der Donk, W. A.
10.64898/2026.05.13.724966 — Posted: 2026-05-14
Spatial distribution of blood-brain barrier membrane proteins is controlled by sorting motifs and physiological signals in vivo
Amick, J., Bhandarkar, S., Wilcox, D. R., Boloker, S., Gu, C.
10.64898/2026.05.10.724157 — Posted: 2026-05-13
δ-catenin controls layer-specific transcriptional maturation of astrocytes via Zbtb20
Sejourne, G., Tan, C. X., Savage, J. T., Manigault, G., Richardson, G., Ding, J., Hardin, E. J., Ramirez, J., Baumert, R., Sakers, K., Eroglu, C.
10.64898/2026.05.12.724361 — Posted: 2026-05-13
First Lithic Age Caribbean genomes document pre-Ceramic genetic continuity and affinities to Central America and northern South America
Sirak, K., Lopez Belando, A. J., Shelley, D., Arevalo, M. G., Shelley, D., Mallick, S., Rohland, N., Reich, D. E.
10.64898/2026.05.12.724636 — Posted: 2026-05-13
AAV tools enable functional modulation and readout of central and peripheral nervous systems in spiny mice
Chung, J. H., Donahue, R. R., Griffiths, J. A., Fan, Y., Lin, C., Chen, X., Dutta, S., Mazmanian, S., Seifert, A. W., Gradinaru, V.
10.64898/2026.05.08.723863 — Posted: 2026-05-13
WATER reveals heterochrony of molecular programs underlies developmental failure caused by minor spliceosome inhibition
Springer, S. M., Boria, A. R., Drake, K. D., Afriyie, K. O., Girardini, K. N., Konakanchi, T., Stevens, I., Camacho, N., Lopes, T., Kanadia, R. N.
10.64898/2026.05.08.723603 — Posted: 2026-05-13
Promoter strength and position govern promoter competition via transcript-dependent insulation
Koska, M., Nagano, M., Swigut, T., Boettiger, A. N., Hansen, A. S., Wysocka, J.
10.1101/2025.05.06.652547 — Posted: 2026-05-13
Replaying germinal center evolution on a quantified affinity landscape
DeWitt, W. S. S., Vora, A. A., Araki, T., Galloway, J. G., Alkutkar, T., Bortolatto, J., Castro, T. B., Dumm, W., Jennings-Schaffer, C., Jia, T., Mesin, L., Ozorowski, G., Pae, J., Ralph, D. K., Bloom, J. D., Nourmohammad, A., Song, Y. S., Ward, A., Starr, T. N., Matsen, F. A., Victora, G. D.
10.1101/2025.06.02.656870 — Posted: 2026-05-12
The transcriptional and translational outcomes for pseudogenes in bacterial endosymbionts
Garber, A., Nwachukwu, J., Stikeleather, R., York, C., McCutcheon, J.
10.64898/2026.02.04.703838 — Posted: 2026-05-12
PCanPIE: A group I intron platform for efficient circRNA synthesis at ambient temperatures
Warkentin, R., Pyle, A. M.
10.64898/2026.05.11.724386 — Posted: 2026-05-12

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