Channel:  The Howard Hughes Medical Institute (HHMI)

1,948 Articles

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Leptin Receptor+ cells create a perisinusoidal niche for thrombopoiesis in the bone marrow by synthesizing CXCL14
Xue, y., Merchant, S., Reyes, A., Luo, M., Zhang, R., Tippetts, T., Grabowski, G., Ngo, T., Zhang, Y., Shang, Z., Jiang, N., Jeffery, E., Li, Y., Wei, T., Gu, W., Du, L., DeBerardinis, R. J., Dean, K. M., Mathews, T. P., Lucas, D. P., Zhao, Z., Morrison, S. J.
10.64898/2026.01.27.702029 — Posted: 2026-01-28
T cell engagers control solid tumors through clonal replacement and IL2-driven effector differentiation of CD8 T-cells
Obenaus, M., Poupault, C. L., McGinnis, C. S., Prange, C., Jiang, H., Su, L. L., Chen, X., Miao, Z., Muldoon, J. J., Yao, W., Waghray, D., Sun, Q., Eyquem, J., Hernandez-Lopez, R. A., Satpathy, A. T., Sage, J., Garcia, K. C.
10.64898/2025.12.04.692214 — Posted: 2026-01-27
The spliceosome assembles on excised linear introns to protect them from degradation
Li, G. W., Wilkinson, M. E., Bartel, D. P.
10.64898/2026.01.21.700889 — Posted: 2026-01-27
Activating Ras-MAPK pathway variants drive hippocampal clonal competition in human epilepsy
Khoshkhoo, S., Bae, M., Wang, Y., Tillett, A., Ramirez, R. B., Finander, B., Egan, E. D., Marx, L., Patel, D., Zhou, Z., Chahine, Y., Chhouk, B., Zoullas, S. M., Lai, A., Coras, R., Bielle, F., Navarro, V., Mathon, B., Valiante, T. A., Chameh, H. M., Gao, A., Krings, T., Gooley, S., Hildebrand, M. S., Bulluss, K., Clark, J., Morokoff, A. P., King, J. A., Todaro, M., Kwan, P., O'Brien, T. J., Berkovic, S. F., Scheffer, I. E., Perucca, P., Lapinskas, E., Rolston, J. D., Cosgrove, G. R., Sarkis, R. A., D'Gama, A. M., Alexadrescu, S., Yang, E., Poduri, A., Richardson, R. M., Erson-Omay, E. Z., DeL
10.64898/2026.01.26.701822 — Posted: 2026-01-27
Evolutionary innovation through fusion of sequences from across the tree of life
Kapoor, R., Schwager, E. E., Phuangphong, S., Rivard, E. L., Kuyyamudi, C., Ghosh, S., Ronai, I., Extavour, C. G.
10.1101/2025.08.30.672725 — Posted: 2026-01-27
Live dynamics of induced cell-cell fusion between mitotic and interphasic cells
Afonso, O., Feliciano, D., Lippincott-Schwartz, J.
10.64898/2026.01.27.700572 — Posted: 2026-01-27
A single-cell atlas of intestinal immune cells across the day-night cycle reveals dynamic populations
Maples, R. W., Quinn, G., Srinivasan, T., Dende, C., Hooper, L. V., Pfeiffer, J. K.
10.64898/2026.01.24.701519 — Posted: 2026-01-26
Comparative Proteomic Profiling of Receptor Kinase Signaling Reveals Key Trafficking Components Enforcing Plant Stomatal Development
Bai, P., Vu, M. H., Komatsu, C., Papoulas, O., Ebine, K., Nozawa, A., Sawasaki, T., Ueda, T., Marcotte, E. M., Torii, K. U.
10.1101/2025.07.20.665823 — Posted: 2026-01-26
Defective splicing of Y-chromosome-linked gigantic genes contributes to hybrid male sterility in Drosophila
Fontan, A., Lannes, R., Fingerhut, J., Flynn, J., Yamashita, Y. M.
10.1101/2025.05.22.655455 — Posted: 2026-01-26
TAK1 integrates the NLRP1 inflammasome into the innate immune response to double-stranded RNA
Corley, M. R., Hyodo, A., Toyoda, H. C., Yonemitsu, M. A., Chantharath, A., Hyde, J. L., Mitchell, P. S.
10.64898/2026.01.23.701331 — Posted: 2026-01-25

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