Channel:  The Howard Hughes Medical Institute (HHMI)

2,121 Articles

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Progressive hypothalamic neuroinflammation after ovariectomy in mice parallels age-related transcriptomic changes in the female human hypothalamus
Bloom, J. C. B., Torres, E., Pereira, S. A., Arvizu-Sanchez, L., Fontes, A. N., Joffe, H., Page, D. C., Navarro, V. M.
10.1101/2024.10.05.616758 — Posted: 2026-03-25
Paleogenomic Evidence for Genetic Heterogeneity and Prior Admixture in Gothic-Associated Communities of Late Antique Bulgaria
Stamov, S., Chobanov, T., Wang, T., Stoeva, K., Momchilov, D., Aladzhov, A., Chobanov, K., Nikolov, M., Nesheva, D., Heather, P., Toncheva, D. I., Zamfirov, M., Lazaridis, I., Reich, D. E., Klasnakov, M., Stamov, G.
10.64898/2026.03.03.709317 — Posted: 2026-03-25
Discovery of a primed endothelial progenitor that requires VEGF/ERK inhibition to complete vein differentiation
Ang, L. T., Zheng, S. L., Liu, K. J., Masaltseva, A., Winters, J., Jha, S. K., Yin, Q., Qian, C., Xiong, X., Dailamy, A., Xi, E., Alcocer, J. C., Sorensen, D. W., She, R., Smolyar, K., Szumska, D., Nornes, S., Martin, R. M., Lesch, B. J., Restrepo, N. K., Sun, W., Weissman, J. S., Lickert, H., Porteus, M. H., Skylar-Scott, M. A., Mosimann, C., Sumanas, S., De Val, S., Red-Horse, K., Loh, K. M.
10.1101/2025.10.11.681838 — Posted: 2026-03-25
HIV-1 infection does not confer intrinsic resistance to cell death induced by cytotoxic T lymphocytes
Bachmann, N., Kim, B., Simonetti, F. R., Kovacs, C. M., Hoh, R., Deeks, S. G., Siliciano, J. D., Siliciano, R. F.
10.64898/2026.03.23.713717 — Posted: 2026-03-25
Bacteriophages target membrane-anchored glycopolymers to promote host cell lysis and progeny release
McKitterick, A. C., Lyerly, E. W., Bernhardt, T. G.
10.1101/2025.06.24.661397 — Posted: 2026-03-25
FoTO1 orchestrates Taxol biosynthesis through catalytic and non-catalytic mechanisms
Wick, C., Somani, A., Liu, J., Karunadasa, S. S., Xu, S.-L., Fordyce, P. M., McClune, C. J., Sattely, E.
10.64898/2026.03.21.713420 — Posted: 2026-03-24
Transcriptomic and functional characterization indicate sexual dimorphism of discrete circadian neuron subtypes
Perez Torres, M., Jiang, R., Ma, D., Herndon, N., Kurmangaliyev, Y. Z., Guo, F., Rosbash, M.
10.64898/2025.12.26.696620 — Posted: 2026-03-23
Inter-individual variation of cellular and gene-expression properties of the human striatum
Burger, S., Yoo, O., Nemesh, J., Muratoglu, E., Vanderburg, C., Yuan, J., Shakir, K., Mello, C. J., Rayan, N. A., Milidantri, J., Kim, K., Drouin, S., Finn, E., Gao, H., Budnik, N., Goldman, M., Fritch, H., Genovese, G., Hogan, M., Catalini, O., Kashin, S., Rockweiler, N., Wysoker, A., Macaisa, L., Reese, L., Flowers, K., Kraft, A. W., Fleming, S. J., Coe, M., Gunaratne, R., Spina, L., Crombie, C., Mohsin, A., Kamitaki, N., Macosko, E. Z., Ichihara, K., McCarroll, S. A.
10.64898/2026.03.20.713160 — Posted: 2026-03-23
Faf1 accelerates p97-mediated protein unfolding by promoting ubiquitin engagement
Liao, Z., Arkinson, C., Martin, A.
10.1101/2025.10.27.684972 — Posted: 2026-03-19
Mechanism and Structure-Guided Optimization of SLC1A1/EAAT3-Selective Inhibitors in Kidney Cancer
Koochaki, P., Qiu, B., Coker, J. A., Earsley, A., Wang, N. S., Romigh, T., Goins, C. M., Salem, C., Mi, D., Days, E., Bauer, J., Stauffer, S. R., Boudker, O., Chakraborty, A. A.
10.1101/2025.07.03.663021 — Posted: 2026-03-19

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