Channel:  The Howard Hughes Medical Institute (HHMI)

1,285 Articles

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High-quality peptide evidence for annotating non-canonical open reading frames as human proteins
Deutsch, E. W., Kok, L. W., Mudge, J. M., Ruiz-Orera, J., Fierro-Monti, I., Sun, Z., Abelin, J. G., Alba, M. M., Aspden, J. L., Bazzini, A. A., Bruford, E., Brunet, M. A., Calviello, L., Carr, S. A., Carvunis, A.-R., Chothani, S., Clauwaert, J., Dean, K., Faridi, P., Frankish, A., Hubner, N., Ingolia, N., Magrane, M., Martin, M. J., Martinez, T. F., Menschaert, G., Ohler, U., Orchard, S., Rackham, O., Roucou, X., Slavoff, S. A., Valen, E., Wacholder, A. C., Weissman, J. S., Wu, W., Xie, Z., Choudhary, J., Bassani-Sternberg, M., Vizcaino, J. A., Ternette, N., Moritz, R. L., Prensner, J., van He
10.1101/2024.09.09.612016 — Posted: 2025-07-24
Comparative Proteomic Profiling of Receptor Kinase Signaling Reveals Key Trafficking Components Enforcing Plant Stomatal Development
Bai, P., Vu, M. H., Komatsu, C., Papoulas, O., Ebine, K., Nozawa, A., Sawasaki, T., Ueda, T., Marcotte, E. M., Torii, K. U.
10.1101/2025.07.20.665823 — Posted: 2025-07-23
Lineage recording in monoclonal gastruloids reveals heritable modes of early development
Regalado, S. G., Qiu, C., Kottapalli, S., Martin, B. K., Chen, W., Liao, H., Kim, H., Li, X., Lalanne, J.-B., Hamazaki, N., Domcke, S., Choi, J., Shendure, J.
10.1101/2025.05.23.655664 — Posted: 2025-07-23
Barcoded monoclonal embryoids are a potential solution to confounding bottlenecks in mosaic organoid screens
Regalado, S. G., Qiu, C., Lalanne, J.-B., Martin, B. K., Duran, M., Trapnell, C., Keith, A., Domcke, S., Shendure, J.
10.1101/2025.05.23.655669 — Posted: 2025-07-23
Temperate phages enhance host fitness via RNA-guided flagellar remodeling
Walker, M. W. G., Richard, E., Wiegand, T., Wang, J., Yang, Z., Casas-Ciniglio, A. A., Hoffmann, F. T., Shahnawaz, H., Gaudet, R. G., Arpaia, N., Fernandez, I. S., Sternberg, S. H.
10.1101/2025.07.22.666180 — Posted: 2025-07-22
Mouse pups lacking a cerebral cortex develop abnormal vocal behavior
Boyd, J. L., Vargas, C., Jarvis, E. D.
10.1101/2025.07.17.665371 — Posted: 2025-07-22
Chromosome scale genomes of two invasive Adelges species enablevirtual screening for selective adelgicides
Glendening, A. M., Stephens, C., Vuruputoor, V. S., Chaganti, T., Myles, M., Stern, D. L., Abdelalim, M., Juang, Y.-P., Hogenhout, S. A., Mathers, T. C., Pauloski, N., Cernak, T. A., Wegrzyn, J. L., Fetter, K. C.
10.1101/2024.11.21.624573 — Posted: 2025-07-22
Pangenome discovery of missing autism variants
Sui, Y., Lin, J., Noyes, M. D., Kwon, Y., Wong, I., Koundinya, N., Harvey, W. T., Wu, M., Hoekzema, K., Munson, K. M., Garcia, G. H., Knuth, J., Wertz, J., Wang, T., Hennick, K., Karunakaran, D., Polo Prieto, R. A., Meyer-Schuman, R., Cherry, F., Pehlivan, D., Suter, B., Gustafson, J. A., Miller, D. E., Human Pangenome Reference Consortium, , Berk-Rauch, H., Nowakowski, T. J., Chakravarti, A., Zoghbi, H. Y., Eichler, E. E.
10.1101/2025.07.21.25331932 — Posted: 2025-07-22
Long-read sequencing of trios reveals increased germline and postzygotic mutation rates in repetitive DNA
Noyes, M. D., Sui, Y., Kwon, Y., Koundinya, N., Wong, I., Munson, K. M., Hoekzema, K., Kordosky, J., Garcia, G. H., Knuth, J., Lewis, A. P., Eichler, E. E.
10.1101/2025.07.18.665621 — Posted: 2025-07-19
Neuroligin-3 interaction with CSPG4 regulates normal and malignant glial precursors through PIEZO1
Gillespie, S. M., Kim, Y. S., Geraghty, A. C., Yalcin, B., Mancusi, R., Hysinger, J., Ivec, A. E., Reed, J., Drexler, R., Quezada, M., Malacon, K., Woo, P. J., Yang, A., Lam, M., Pan, Y., Zuchero, J. B., Trotter, J., Monje, M.
10.1101/2025.07.12.664340 — Posted: 2025-07-17

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