Channel:  The Howard Hughes Medical Institute (HHMI)

1,895 Articles

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Ectopic engraftment of nociceptive neurons derived from hPSCs for pain relief and joint homeostasis
Dong, X., Lee, G., Wang, Z. P., Zhang, W., Cao, X., Peng, J., Wang, J., Wu, Z.
10.64898/2025.12.16.694733 — Posted: 2025-12-19
In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibitors on LRRK2 filament formation and microtubule association
Basiashvili, T., Hutchings, J., Chen, S., Karasmanis, E. P., Flaherty, W. A., Leschziner, A. E., Villa, E.
10.64898/2025.12.18.694444 — Posted: 2025-12-19
VEGF/ERK activation and PI3K inhibition together drive a vein-to-artery transition in an in vitro model of human angiogenesis
Amir-Ugokwe, Z., Red-Horse, K., Loh, K. M., Ang, L. T., Pyke, A., Trimm, E., Chakraborty, M., Fan, X.
10.64898/2025.12.17.694993 — Posted: 2025-12-19
Characterizing the informativeness of pathogen genome sequence datasets about transmission between population groups
Tran-Kiem, C., Perofsky, A. C., Lessler, J., Bedford, T.
10.1101/2025.08.07.25333239 — Posted: 2025-12-18
Spatial gene expression maps in vertebrate limbs display conserved and regenerative species-specific features within connective tissue
McMann, C. L., Park, C., Cloutier, J. K., Reddien, P.
10.64898/2025.12.15.694399 — Posted: 2025-12-17
Antibody Mediated Diversification of Primary and Secondary Immune Responses
Schaefer-Babajew, D., Binet, L., Santos, G. S. S., Ruprecht, C., Deimel, L. P., ElTanbouly, M. A., Gharrassi, D., Uhe, C., Yao, K.-H., Hernandez, B., Agrawal, P., Gazumyan, A., Stamatatos, L., Hartweger, H., Nussenzweig, M. C.
10.64898/2025.12.15.694384 — Posted: 2025-12-17
Humanized Extracellular Vesicles for Efficient RNA Delivery
Ma, X., Zhao, S. R., Cepko, C. L.
10.64898/2025.12.15.694436 — Posted: 2025-12-17
Nanopore-based profiling of PEGylation in nucleic acid therapeutics
Patino Guillen, G., Schmidt, T. T., Baumberg, J. J., Szostak, J. W., Keyser, U. F., Boskovic, F.
10.64898/2025.12.15.694309 — Posted: 2025-12-17
Human acrocentric chromosome short arm de novo mutation and recombination
Lin, J., Mastrorosa, F. K., Noyes, M. D., Yoo, D., Rhie, A., Porubsky, D., Hoekzema, K., Munson, K. M., Koundinya, N., Watkins, W. S., Jorde, L. B., Quinlan, A. R., Neklason, D. W., Phillippy, A. M., Eichler, E. E.
10.64898/2025.12.16.694519 — Posted: 2025-12-17
Mitochondria-derived PEP licenses glycerolipid synthesis via SLC25A35
Yamamuro, T., Katoh, D., Silva, G. M., Nishida, H., Oikawa, S., Higuchi, Y., Wang, D., Fujimoto, M., Yoshida, N., Li, M., Shin, J., Zhao, Z., Yook, J.-S., Sun, L., Kajimura, S.
10.64898/2025.12.12.693842 — Posted: 2025-12-16

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