Channel:  The Howard Hughes Medical Institute (HHMI)

2,386 Articles

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Pathogenic MYBPC3 missense variants alter protein-protein interactions within the sarcomere
Thompson, A. D., Pankiewicz, C., Plenge, L. S., Lilienthal, U., Kotaru, S., Vignesh, M., Phan, T., McAllister, C., Yob, J., Morley, M. P., Ingles, J., Hespe, S., Helms, A. S., Ginsburg, D., SHaRe-HCM Investigators, , Day, S. M.
10.64898/2026.05.27.727676 — Posted: 2026-07-21
Identifying endogenous substrates of the 26S proteasome through site-specific photocrosslinking
Martin, A., Yori Restrepo, S.
10.64898/2026.07.19.739412 — Posted: 2026-07-20
Lack of specificity of planarian progenitor responses to injury in regeneration
Pellegrini, C. E., Reddien, P. W.
10.64898/2026.02.19.706786 — Posted: 2026-07-20
Spatially resolved cellular and circuit architecture of the insular cortex controlling different dimensions of pain
Xie, G., Wang, M., Liu, Y., Zhang, Y.
10.64898/2026.07.15.738697 — Posted: 2026-07-20
Molecular basis of ubiquitin-independent recognition and degradation of ODC/Antizyme by the 26S proteasome
Martin, A., Ramos-Ortiz, D. R., Hsieh, H.-H., Dong, K. C.
10.64898/2026.07.19.739413 — Posted: 2026-07-20
Genome-wide chromatin recording resolves dynamic cell state changes
Takei, Y., Lay, J. A., Linton, J. M., Chadly, D. M., Ochiai, Y., Hadas, R., Perez, A. A., Blanco, M. R., Laurino, P., Guttman, M., Elowitz, M. B.
10.1101/2025.08.05.668773 — Posted: 2026-07-19
Stepwise DNA unwinding gates TnpB genome-editing activity
Zhou, Z., Saffarian-Deemyad, I., Shi, H., Weiss, T., ur-Rehman, M. M., Vohra, K., Skopintsev, P., Yoon, P. H., Trinidad, M. I., Langeberg, C. J., Kamalu, M., Amerasekera, J., Zhou, Y., Doherty, E. E., Aris, K. D. P., Al-Sayyad, N., Thornton, B. W., Weissman, R. F., Wasko, K. M., Esain-Garcia, I., DeTurk, E. C., Savage, D. F., Jacobsen, S. E., Bryant, Z., Doudna, J. A.
10.64898/2026.01.09.698545 — Posted: 2026-07-18
Human vault RNAs exhibit diverse expression patterns and inter-locus compensation
Hemphill, W. O., Zaug, A. J., Hecht, C. J. S., Cech, T. R.
10.64898/2026.06.17.732918 — Posted: 2026-07-18
Whole-body single-cell atlas of an adult vertebrate in homeostasis and regeneration
Atabay, K. D., Aoude, P., Park, C., Kadobianskyi, M., Paugois, O. H., Judkewitz, B., Reddien, P.
10.64898/2026.02.03.703562 — Posted: 2026-07-17
Transcriptomic data and biomedical literature synergize in finding pharmacologic gene regulators
Deisseroth, C. A., Brazelton, B., Shaik, Z., Sandberg, B. S., Liu, Z., Zoghbi, H. Y.
10.64898/2026.03.13.708862 — Posted: 2026-07-17

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