Channel:  The Howard Hughes Medical Institute (HHMI)

2,690 Articles

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Elevated polyadenylated histone gene transcription in human cancer
Paranal, R. M., Bryson, T. D., Rios Rios, G. N., Nguyen, K. K., Ahmad, K., Henikoff, S.
10.64898/2026.10.14.758961 — Posted: 2026-10-20
Reliable and Efficient Agentic Protein Design with Toolset Harnessing
Butcher, J., Chen, J., Hunt, A., Haas, C. M., Dai, W., Sharma, S., Mitra, R., Salike, S., Koob, J., Muraishi, A., Li, Z., Pyles, H., Tyka, M. D., Bauer, M. S., Brent, R. I., Mittal, A., King, N. P., Baker, D.
10.64898/2026.10.19.759896 — Posted: 2026-10-20
Design of synthetic activators for programmable gene expression
Chen, W., Jiao, R., Coventry, B., Qu, X., Bauer, M., Tran, L., Tcheau, T., Wu, K., Song, Z., Roullier, N., Li, X., Glasscock, C., Hilton, I. B., Baker, D.
10.64898/2026.10.19.760300 — Posted: 2026-10-20
Spatial isotope tracing maps compartmentalized nutrient use across the adult fruit fly
Moon, S. J., Huang, K., Blum, J. L. E., New, C., Park, Y., Chen, Y., Nishida, H., Pister, V. I., Nahid, M. A., Hu, Y., Tennessen, J., Fraenkel, E., Asara, J. M., Davidson, S. M., Perrimon, N.
10.64898/2026.10.06.757091 — Posted: 2026-10-20
Hyperactivation of β-catenin rewires mitochondrial fuel selection in liver cancer cells
Cedeno-Rosario, L., Alcantara, Q. A., Sierra, N. A., Prasad, P., Wright, J., Lam, G., Abdi, N., Florence, J., Bott, A. J., Heyden, K., Youngs, J. C., Narbona-Perez, A. J., Mena, L. G., Makurath, M. A., Velasco-Silva, J. N., Jeong, M.-Y., Fogarty, S., Ducker, G. S., Lippincott-Schwartz, J., McReynolds, M. R., Rutter, J.
10.64898/2026.10.18.759986 — Posted: 2026-10-20
Holistic Design of Selective Photoenzymes with Genetically Programmed Sensitizers
Hardy, F. J., Crawshaw, R., Dider, C., Kohn, A. R., Gallois, F. J., Lauko, A., Pellock, S. J., Kalvet, I., Green, A. P., Baker, D.
10.64898/2026.10.16.759720 — Posted: 2026-10-19
High-Throughput Screening Identifies Proteasome Inhibitors as Potentiators of Type III Interferon JAK-STAT Signaling and Antiviral Immunity
Parisien, J.-P., O Leary, C., Shabani, S., Fernandez-Dunne, S., Huynh, L. T., Kurowska, A. K., Horvath, C. M., Mendoza, J. L.
10.64898/2026.10.12.758093 — Posted: 2026-10-19
Heteromeric LGP2-MDA5 receptor complexes drive antiviral signaling
Buchel, G., Xu, L., Sung, Y.-C., Pyle, A. M.
10.64898/2026.08.20.745998 — Posted: 2026-10-19
DNAJC13 restricts TLR7-driven autoimmunity in mice and humans
Rael, V. E., Yano, J. A., Slayden, L. C., Roberts, A. W., Brian, B. F., Ruivo, P. R., Lewandowski, L. B., Hiraki, L. T., Barton, G.
10.64898/2026.10.13.758957 — Posted: 2026-10-19
Non-cell-autonomous removal of protein aggregates via trogocytosis
Kimura, Y., Sato, K., Chavan, A. R., Kasberg, W., Silva, M., Qiu, W., Iyer, N., Innerberger, M., Siwanowicz, I., Pope, S. D., Rangavajhula, A., Yao, G.-Q., Insogna, K., Trautman, E. T., Bleck, C. K., su, x., Lippincott-Schwartz, J., Medzhitov, R.
10.64898/2026.10.13.758691 — Posted: 2026-10-19

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