Channel:  The Howard Hughes Medical Institute (HHMI)

2,104 Articles

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Combining brain-wide activity imaging with electron microscopy reveals a distributed nociceptive network in the brain
Randel, N., Wang, C., Clayton, M. S., Wang, K., Pang, S., Xu, S. C., Champion, A., Hess, H. F., Cardona, A., Keller, P. J., Zlatic, M.
10.1101/2025.09.25.678485 — Posted: 2026-03-19
Genome-scale functional mapping of the mammalian whole brain with in vivo Perturb-seq
Shi, T., Korshunova, M., Kim, S., DeTomaso, D., Zheng, X., Vishvanath, L., Nyasulu, T., Huynh, N., Sun, A., Thompson, P. C., Zhang, Y., Wigdor, E. M., Rohani, N., Ali, S., Qiu, H., Geralt, M., Zhao, Z., Rabhi, S., Yao, Z., van Velthoven, C. T., Nery, J. R., Castanon, R. G., Dicks, S., Chen, T. J., Ecker, J. R., Zeng, H., Zheng, G. X., Sanders, S. J., Sundaram, L., Jin, X.
10.64898/2026.03.16.711480 — Posted: 2026-03-18
Influenza hemagglutinin subtypes have different sequence constraints despite sharing extremely similar structures
Ahn, J. J., Yu, T. C., Dadonaite, B., Radford, C. E., Bloom, J. D.
10.64898/2026.01.05.697808 — Posted: 2026-03-18
Midgestation metabolic constraint in purine metabolism drives distinct strategies for placenta and fetal growth
Xu, W., De La Cruz, N., Woods, A., Lokshtanov, D., Gao, S., Khan, N. A., Wright, S., Florian-Rodriguez, M., McIntire, D. D., Duryea, E. L., Nelson, D. B., Spong, C. Y., Herrera, C. L., Hanna, J. H., Srivatsan, S. R., Aguilera Castrejon, A., Solmonson, A.
10.64898/2026.03.18.712680 — Posted: 2026-03-18
Divergent C. elegans toxin alleles are suppressed by distinct mechanisms
Zdraljevic, S., Walter-McNeill, L., Bruni, G., Marquez, H., Collins, J., Leighton, D. H. W., Alexander, N., Bloom, J. S., Kruglyak, L.
10.1101/2024.04.26.591160 — Posted: 2026-03-18
Optogenetic Analysis of Behavior in the Mosquito Aedes aegypti
Rami, S., So, M., Travis, C., Jiao, Y., Shamble, P., Sorrells, T. R.
10.64898/2026.03.15.711871 — Posted: 2026-03-18
Heterotypic intercellular adhesion tunes efficiency of cell-on-cell migration
Kuyyamudi, C., Ghosh, S., Extavour, C. G.
10.1101/2025.08.29.673192 — Posted: 2026-03-18
Reconstituting Mouse Embryogenesis Ex Utero from Gastrulation to Fetal Development Reveals Maternally Independent Metabolic Programs
Lokshtanov, D., Gao, S. M., Xu, W., Kosman, A., Roncato, F., De La Cruz, N., Khan, N. A., Woods, A., Campbell, I., Woehler, A., Christoforou, C., Ding, L., Hu, A., Copeland, M., Wang, L., Yang, X., Raley, C., Delventhal, K., Herrera, A., Valente, A., Wright, S., Gomez-Cesar, E., Shlomo, R., Golenchenko, S., Oldak, B., Yilmaz, A., Gurhan-Sevinc, G., Comar, M.-Y., Viukov, S., Novershtern, N., Zhang, H., Duong, T., Li, L., Khatib, N., Kakun, R. R., Espinosa-Medina, I., Florian-Rodriguez, M. E., LaManno, G., Tillberg, P. W., Wang, M. C., Maza, I., Srivatsan, S., Solmonson, A., Hanna, J. H., Aguile
10.64898/2026.03.17.710314 — Posted: 2026-03-18
The Drosophila ovary produces two waves of adult follicles and a novel pupal wave that turns over
Fu, W. Y., Spradling, A. C.
10.1101/2025.11.11.687893 — Posted: 2026-03-18
UFMylation of Pyruvate Dehydrogenase Regulates Mitochondrial Metabolism
Nguyen, P. T., Wu, Z., Kim, D., Ogu, T., Yin, S., Sondhi, V., Cai, F., Tippetts, T. S., Jen, A., Shishkova, E. J., Cai, L., Dumesnil, D., Cervantes, M., Chen, H., Mishra, P., Coon, J., Hoxhaj, G., Ni, M., DeBerardinis, R. J.
10.64898/2026.03.18.712693 — Posted: 2026-03-18

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