Channel:  The Howard Hughes Medical Institute (HHMI)

2,389 Articles

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A membrane homeostatic response to lipid overload coordinates fatty acid metabolism
Xiang, X., Ambaw, Y. A., Tok, O., Hui, S., Tang, W.-c., Mizrak, A., Zhang, Q., Cohen-Abeles, L., Farese, R. V., Walther, T. C.
10.64898/2026.06.10.731409 — Posted: 2026-07-10
AAV delivered lysosome-targeting chimeras mediate sustained antibody depletion in vivo
Yang, J. L., Loh, K. Y., Sandoval Espinoza, C. R., Schuster, D., Deisseroth, K., Bertozzi, C. R.
10.64898/2026.07.05.736665 — Posted: 2026-07-10
Regulatory architecture controlling terminal differentiation of an interoceptive paraneuron in C. elegans
Ji, H., Vidal, B., Conklin, E., Enkhtuvshin, T., Schroeder, N. E., Hobert, O.
10.64898/2026.05.28.728471 — Posted: 2026-07-09
Spectral envelopes of facial movements predict intention, cortical representations, and neural prosthetic control
Hakim, R., Jaggi, A., Heo, G., Matsumoto, H., Uchida, N., Watabe-Uchida, M., Datta, S. R., Musall, S., Sabatini, B. L.
10.1101/2025.09.10.675423 — Posted: 2026-07-09
AI-enabled Spatial Profiling of Circulating Tumor-Immune Ecosystems Predicts Patient Outcomes Across Cancers
Squires, J. R., Sun, Y., Hoffmann, A., Zhang, Y., Pan, H., Tong, F., He, Y., Scholten, D., Almubarak, H., Gurley, M., Minor, A., Singh, A., Zhang, J., Ding, H., Mao, C., Platanias, L. C., Yu, J., Hussain, M., Luo, Y., Gradishar, W. J., Cristofanilli, M., Cooper, L. A. D., Zhao, L., Fang, D., Stringer, C., Liu, H.
10.64898/2026.07.02.736133 — Posted: 2026-07-09
Multi-region coordination of evidence accumulation and decision commitment in the brain
Bondy, A. G., Charlton, J. A., Luo, T. Z., Kopec, C. D., Stagnaro, W. M., Venditto, S. J. C., Shi, K., Xie, E. Y., Beau, M., Lynch, L., Janarthanan, S., Oline, S. N., Harris, T. D., Brody, C. D.
10.1101/2024.08.21.609044 — Posted: 2026-07-09
Coupling of tubulin acetylation to microtubule stabilization through molecular mimicry
Perez-Bertoldi, J. M., Dang, T. m. J., Golcuk, M., Lanska, E., Lopes, D., Henriot, V., Luo, J., Zhang, R., Ti, S.-C., Janke, C., Lansky, Z., Gur, M., Del Bene, F., Nogales, E.
10.64898/2026.07.08.736797 — Posted: 2026-07-09
Anti-CAR Immunity Drives Acquired Therapeutic Resistance to GD2-CAR T Cell Therapy in Diffuse Midline Glioma
Chen, Y., Reynolds, K., Koch, M. R. A., Petrakian, C. F., Good, Z., Yamada-Hunter, S., Sotillo, E., Song, K.-W., Mahdi, J., Majzner, R., Desai, M. H., Huang, Y.-W., Daghagh, H., Ehlinger, Z. J., Iswari, N., Sabatti, C., Baggott, C., Rietberg, S. P., Mo, K. C., Tsui, K. C. Y., Hamilton, M. P., Egeler, E., Moon, J., Erickson, C., Jacobs, A., Duh, A. K., Beebe, B., Carr, C., Fujimoto, M., Kunicki, M., Lim, A. S., Li, A., Brown, A. K., Kuo, A., Kaur, A., Soundaranayagi, S. R., Prabhu, S., Grant, G., Prolo, L. M., Campen, C., Partap, S., Davis, K. L., Feldman, S. A., Tunuguntla, R., Cochran, J. R.
10.64898/2026.06.25.26356492 — Posted: 2026-07-09
Single-molecule imaging reveals cytoplasmic translation of P granule-enriched mRNAs in C. elegans
Simmons, W. R., Geng, Q., Miller, S. I., Griffin, E., Seydoux, G.
10.64898/2026.07.01.735846 — Posted: 2026-07-09
Benzoxaboroles are structurally unique binders of eukaryotic translation initiation factor 4E
Combs, J. B., Peacock, D. M., Craven, G. B., Jung, S., Chen, Y., Le, S. M., Taunton, J., Shokat, K.
10.64898/2026.02.24.707563 — Posted: 2026-07-09

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