Channel:  The Howard Hughes Medical Institute (HHMI)

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Transcriptomic and functional characterization indicate sexual dimorphism of discrete circadian neuron subtypes
Perez Torres, M., Jiang, R., Ma, D., Herndon, N., Kurmangaliyev, Y. Z., Guo, F., Rosbash, M.
10.64898/2025.12.26.696620 — Posted: 2026-03-23
Inter-individual variation of cellular and gene-expression properties of the human striatum
Burger, S., Yoo, O., Nemesh, J., Muratoglu, E., Vanderburg, C., Yuan, J., Shakir, K., Mello, C. J., Rayan, N. A., Milidantri, J., Kim, K., Drouin, S., Finn, E., Gao, H., Budnik, N., Goldman, M., Fritch, H., Genovese, G., Hogan, M., Catalini, O., Kashin, S., Rockweiler, N., Wysoker, A., Macaisa, L., Reese, L., Flowers, K., Kraft, A. W., Fleming, S. J., Coe, M., Gunaratne, R., Spina, L., Crombie, C., Mohsin, A., Kamitaki, N., Macosko, E. Z., Ichihara, K., McCarroll, S. A.
10.64898/2026.03.20.713160 — Posted: 2026-03-23
Quinone reductase 2 reads H3 serotonylation to support neuronal maturation
Chen, M., Yang, C., Li, X., Kong, L., Weekley, B. H., Wei, X., O'Chan, J. C., Vinson, D. A., Cetin, B., Ramakrishnan, A., Shen, L., Zeng, R., Liu, Z., Zhang, J., Cappuccio, K. M., Sokol, J. R., Baljinnyam, E., Hu, R., Rosenblum, K., Molina, H., Zheng, Q., David, Y., Marro, S. G., Muir, T. W., Li, X. D., Li, H., Maze, I.
10.64898/2026.03.17.712426 — Posted: 2026-03-19
Combining brain-wide activity imaging with electron microscopy reveals a distributed nociceptive network in the brain
Randel, N., Wang, C., Clayton, M. S., Wang, K., Pang, S., Xu, S. C., Champion, A., Hess, H. F., Cardona, A., Keller, P. J., Zlatic, M.
10.1101/2025.09.25.678485 — Posted: 2026-03-19
Faf1 accelerates p97-mediated protein unfolding by promoting ubiquitin engagement
Liao, Z., Arkinson, C., Martin, A.
10.1101/2025.10.27.684972 — Posted: 2026-03-19
Mechanism and Structure-Guided Optimization of SLC1A1/EAAT3-Selective Inhibitors in Kidney Cancer
Koochaki, P., Qiu, B., Coker, J. A., Earsley, A., Wang, N. S., Romigh, T., Goins, C. M., Salem, C., Mi, D., Days, E., Bauer, J., Stauffer, S. R., Boudker, O., Chakraborty, A. A.
10.1101/2025.07.03.663021 — Posted: 2026-03-19
The Drosophila ovary produces two waves of adult follicles and a novel pupal wave that turns over
Fu, W. Y., Spradling, A. C.
10.1101/2025.11.11.687893 — Posted: 2026-03-18
UFMylation of Pyruvate Dehydrogenase Regulates Mitochondrial Metabolism
Nguyen, P. T., Wu, Z., Kim, D., Ogu, T., Yin, S., Sondhi, V., Cai, F., Tippetts, T. S., Jen, A., Shishkova, E. J., Cai, L., Dumesnil, D., Cervantes, M., Chen, H., Mishra, P., Coon, J., Hoxhaj, G., Ni, M., DeBerardinis, R. J.
10.64898/2026.03.18.712693 — Posted: 2026-03-18
Genome-scale functional mapping of the mammalian whole brain with in vivo Perturb-seq
Shi, T., Korshunova, M., Kim, S., DeTomaso, D., Zheng, X., Vishvanath, L., Nyasulu, T., Huynh, N., Sun, A., Thompson, P. C., Zhang, Y., Wigdor, E. M., Rohani, N., Ali, S., Qiu, H., Geralt, M., Zhao, Z., Rabhi, S., Yao, Z., van Velthoven, C. T., Nery, J. R., Castanon, R. G., Dicks, S., Chen, T. J., Ecker, J. R., Zeng, H., Zheng, G. X., Sanders, S. J., Sundaram, L., Jin, X.
10.64898/2026.03.16.711480 — Posted: 2026-03-18
Influenza hemagglutinin subtypes have different sequence constraints despite sharing extremely similar structures
Ahn, J. J., Yu, T. C., Dadonaite, B., Radford, C. E., Bloom, J. D.
10.64898/2026.01.05.697808 — Posted: 2026-03-18

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