Channel:  The Howard Hughes Medical Institute (HHMI)

1,843 Articles

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A genetic screen in enteroendocrine cells reveals mechanisms that control protein sensing and GLP-1 release
Yu, S., Lee, Y., Boggess, S. C., Klein, N. R., Teyssier, N., Kampmann, M., Knight, Z. A.
10.64898/2025.11.30.691441 — Posted: 2025-12-02
Need-selective gating of dopamine neuron cue responses by real and virtual hunger
Mamaligas, A. A., Berke, J., Kreitzer, A. C., Knight, Z. A.
10.64898/2025.11.29.691326 — Posted: 2025-12-02
High-throughput neutralization measurements correlate strongly with evolutionary success of human influenza strains
Kikawa, C., Loes, A. N., Huddleston, J., Figgins, M. D., Steinberg, P., Griffiths, T., Drapeau, E. M., Peck, H., Barr, I. G., Englund, J. A., Hensley, S. E., Bedford, T., Bloom, J. D.
10.1101/2025.03.04.641544 — Posted: 2025-12-02
D. melanogaster meiotic driver Stellate compromises sperm development by impeding nuclear envelope remodeling
Meng, X. M., Yamashita, Y. M.
10.1101/2025.09.29.679412 — Posted: 2025-12-02
Naegleria amoebae seek confinement and crawl persistently through narrow spaces
Velle, K., Ramaswamy, M., Hokmabad, B. V., Martin-Perez, T., Carrasco, T. T., Callahan, W. S., Kim, H. S., Datta, S. S., Edwards, M., Fritz-Laylin, L.
10.1101/2025.11.30.691445 — Posted: 2025-12-01
Sleep controls peroxisomal abundance to reduce wake-induced brain oxidation
Guevara, C., Li, Y., Pyfrom, E. S., Killiany, S., Yue, Z., Sehgal, A.
10.1101/2025.11.28.691144 — Posted: 2025-12-01
Molecular interplay between the DNA damage checkpoint kinase Mec1-Ddc2 and its activator Dpb11 on gapped DNA
Beckwitt, E. C., Chua, G. N. L., Liu, S., O'Donnell, M. E.
10.1101/2025.11.28.691181 — Posted: 2025-11-30
Orthosteric Molecular Glue Inhibits COP9 Signalosome with Substrate-Dependent Potency
Shi, H., Wang, X., Yu, C., Mao, H., Jiao, F., Braitbard, M., Shor, B., Zhang, Z., Hinds, T. R., Cao, S., Fan, E., Schneidman-Duhovny, D., Huang, L., Zheng, N.
10.1101/2025.11.26.690573 — Posted: 2025-11-30
Ultrafast CTCF dynamics control cohesin barrier function
Rudnizky, S., Murray, P. J., Sorensen, E. W., Koenig, T. J. R., Pangeni, S., Merino-Urteaga, R., Chhabra, H., Caccianini, L., Davidson, I. F., Osorio-Valeriano, M., Hook, P. W., Meneses, P., Hao, J., Zarb, J. S., Hatzakis, N. S., Timp, W., Farnung, L., Vos, S. M., Peters, J.-M., Aksimentiev, A., Ha, T.
10.1101/2025.11.25.690553 — Posted: 2025-11-29
Early-life stromal niches orchestrate B lymphopoiesis at the brain's borders
Walker, A. J., Fisher, T. M., Caldwell, S. K., Gupte, A. S., Colville-Reimertz, J. M., Sabikunnahar, B., Marsh, S. E., de Soysa, Y., Gazestani, V. H., Walker, A. C., Huang, Y., Mavinkurve, A. V., Barr, H. J., Lanser, T. B., Murphy, S., Bowling, S., Dissing-Olesen, L., Camargo, F. D., Stevens, B.
10.1101/2025.11.27.690844 — Posted: 2025-11-29

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