Channel:  The Howard Hughes Medical Institute (HHMI)

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UnionLoops: a workflow for calling chromatin loops across related Hi-C datasets with improved specificity, precision, and sensitivity
Liu, J., Gibcus, J. H., Dekker, J.
10.64898/2026.01.19.700311 — Posted: 2026-01-20
PfApiAT2 is a proline transporter essential for the transmission of Plasmodium falciparum by the mosquito vector.
Khushu, M., Kissel, R. C., Kauffman, J., Taccheri, C., Singh, N., Summers, R. L., Plant, L. D., Wirth, D., Catteruccia, F., Bopp, S.
10.64898/2026.01.20.700404 — Posted: 2026-01-20
Structural and Spectroscopic Basis for Catalysis by a Class C Radical S-adenosylmethionine Methylase Involved in Nosiheptide/Nocathiacin Biosynthesis
Wang, B., Knox, H. L., York, N. J., Radle, M. I., Silakov, A., Booker, S. J.
10.64898/2026.01.19.700444 — Posted: 2026-01-20
Decoding the cell intrinsic and extrinsic roles of PRC2 in early embryogenesis
Zhou, C., Wang, M., Chen, Z., Zhang, Y.
10.64898/2026.01.20.700679 — Posted: 2026-01-20
Selective Immune Silencing by Targeted TGF-β Agonists
Sun, Q., Ogishi, M., Jiang, H., Barrett, A. K., Yan, H., Sola, E., Zhang, J., Xiao, P., Lyu, H., Salehi, A., Tang, Q., Lanz, T. V., Davis, M. M., Negrin, R. S., Garcia, K. C.
10.64898/2026.01.19.700410 — Posted: 2026-01-20
Inefficient autophagosome formation limits the temporal dynamics of OPTN-mediated mitophagy in neurons
Green, J. R., Gooden, M. K., Ojo, A. E., Kalejaiye, T. D., Evans, C. S.
10.64898/2026.01.16.700014 — Posted: 2026-01-20
Establishing the molecular basis for MDA5 mutation-linked autoimmunity
Xu, L., Chung, K., Guo, R., Pan, A., Pyle, A.
10.64898/2026.01.20.700587 — Posted: 2026-01-20
Cytoplasmic mRNA decay by the anti-viral nuclease RNase L promotes transcriptional repression
Mao, X., Tokamov, S., Pahmeier, F., Lari, A., Xu, J., Harris, E., Glaunsinger, B.
10.1101/2025.07.08.663778 — Posted: 2026-01-19
Modular mRNA LNP design integrates RNA, lipid, and antigen engineering for protective vaccination
Farzani, T., Espinoza, N., M. Manafi, M., R. Welch, S., D. Coleman-McCray, J., Aida-Ficken, V., R. Spengler, J., Bergeron, E., F. Spiropoulou, C., Borges, C., Bielecki, K., Li, L., Shah, D., Paye, M., Rojas, E., N. Spector, S., Samani, P., E. Hensley, L., Ozonoff, A., Sabeti, P.
10.64898/2026.01.17.699915 — Posted: 2026-01-18
B Lymphocyte Protein Factories produced by Hematopoietic Stem Cell Gene Editing
Hartweger, H., Ruprecht, C., Yao, K.-H., Laffont, P., Lima dos Reis, G., Zhou, P., Hägglöf, T., Binet, L., Loewe, M., Hong, J. P., Xiao, T., Sefik, E., Hernandez, B., Gazumyan, A., Jankovic, M., Seaman, M. S., Costa, G., Nelson, S. A., Clark, J., Kanatani, S., Wilson, P. C., Krammer, F., Levashina, E. A., Julien, J.-P., Wardemann, H., Sinnis, P., Stamatatos, L., Flavell, R. A., Nussenzweig, M. C.
10.64898/2026.01.16.699998 — Posted: 2026-01-18

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