Channel:  The Howard Hughes Medical Institute (HHMI)

2,254 Articles

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The Structural Basis of Malodorant Skatole Formation by the Glycyl Radical Enzyme Indoleacetate Decarboxylase
Imrich, C. N., Backman, L. R. F., Allworth, A. P., Andorfer, M. C., Paris, J. C., Greeley, N. M., Fu, B., Balskus, E. P., Drennan, C. L.
10.64898/2026.05.24.727522 — Posted: 2026-05-25
Combined Disruption of Multiple Cytokine Signaling Pathways Enables One-Step Anterograde Tracing with Vesicular Stomatitis Virus
Ma, X., Cepko, C. L.
10.64898/2026.05.22.727255 — Posted: 2026-05-25
Amino Acids in the RSSY Motif of Lipoyl Synthase Control Substrate Binding and Reactivity
Jeyachandran, V., Lanz, N., Pandelia, M.-E., Rectenwald, J., Pendyala, J., Boal, A., Krebs, C., Booker, S.
10.64898/2026.05.25.727706 — Posted: 2026-05-25
PIEZO1-mediated mechanosensation links aging to bladder dysfunction
Hamed, Y. M. F., Joshi, V., Wilhelm, K., Romero, L. O., Solomon, O. D., Kwok, T. B., Lopez Gonzalez, E. D., Ridlon, M. M., Pendyala, S., Calhoun, C. M., Martinez, A. E., Asmussen, J. K., Keil Stietz, K., Vezina, C. M., Vasquez, V., Lichtarge, O., Beyder, A., Marshall, K. L.
10.64898/2026.05.24.726025 — Posted: 2026-05-25
Spatial Regulation of CAR Signaling Enables Logic-Gated Activity
Nichakawade, T. D., Mog, B., Pearlman, A. D., Ahmedna, T. S., Marcou, N., Mora-Cartin, R., Watson, E., Seok Lee, B., DiNapoli, S. R., Papadopoulos, N., Bettegowda, C., Dal Molin, M., Wirtz, D., Pardoll, D. M., Paul, S., Sur, S., Gabrielson, K. L., Zhou, S., Vogelstein, B., Kinzler, K. W.
10.64898/2026.05.22.726983 — Posted: 2026-05-24
How many genes can CRISPR edit to engineer complex adaptations?
Kyung, J., Esfahanian, M., Mann, J., Koke, E., Pham, K., Peng, Y., Exposito-Alonso, M.
10.64898/2026.05.21.726991 — Posted: 2026-05-23
Entrenchment of germline amino-acid differences in antibody affinity maturation
Harel, N., Sung, K., Dumm, W., Johnson, M. M., Rich, D., Fukuyama, J., Haddox, H. K., Matsen, F. A.
10.64898/2026.04.21.720000 — Posted: 2026-05-23
Developmental conversion of the nucleolus into an RNA Polymerase II transcriptional platform in Drosophila spermatocytes
Fingerhut, J. M. M., Park, J. I., Li, R. Y., Lannes, R., Ashok, A., Yamashita, Y. M.
10.64898/2026.05.20.726666 — Posted: 2026-05-23
Molecular underpinning of Hydra viridissima-algal facultative symbiosis and vertical algal transmission
Tran, J. R., Sittmann, J., Ma, B., Zhu, M., Zheng, Y., Hu, M.
10.64898/2026.05.21.726902 — Posted: 2026-05-23
De novo design of RNA pseudoknots with deep learning
Townley, J., Kladwang, W., Baker, D., Blair, H. M., Choe, C., El Nesr, G., Favor, A., Fisker, E., Haack, D. B., He, S., Hingey, J., Huang, R., Huang, P.-S., Joshi, C. K., Karagianes, T. G., Kubaney, A., Lio, P., Mancino, A., Romano, J., Rudolfs, B., Spellmon, N., Toor, N., Wu, V., Yu, Z., Eterna players, , Das, R.
10.64898/2026.05.21.726960 — Posted: 2026-05-22

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