Channel:  The Howard Hughes Medical Institute (HHMI)

1,285 Articles

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Whole-transcriptome-scale and isoform-resolved spatial imaging of single cells in complex tissues
Cohen, L., Halpern, A., Blosser, T. R., Che, P., Pan, X., Zhuang, X.
10.1101/2025.08.27.672533 — Posted: 2025-08-30
The Kaposi's sarcoma-associated herpesvirus TBP mimic uses a non-canonical DNA binding mode to promote viral late gene transcription
Llacsahuanga Allcca, L. E., Didychuk, A. L., Rodriguez-Vargas, A., Glaunsinger, B.
10.1101/2025.08.25.672222 — Posted: 2025-08-29
Impact of 2'-deoxyribo-purine substrates on nonenzymatic RNA template-directed primer extension
Fang, Z., Acikgoz, O., Jia, X., Essex, J., Wen, R., Szostak, J. W.
10.1101/2025.08.29.673048 — Posted: 2025-08-29
A conserved electron transport chain sensitizes Bacteroides to a pore-forming type VI secretion toxin
Ratner, H. K., Duong, B. D., Miao, P., Bertolli, S., Shen, B. A., Mitchell, U., Gallagher, L. A., Radey, M., Peterson, S. B., Mougous, J.
10.1101/2025.08.29.672963 — Posted: 2025-08-29
Discovery of homoharringtonine pathway enzymes reveals a whole plant model for coordinated biosynthesis
Dho, Y., Smith, K., Sattely, E. S.
10.1101/2025.08.26.672243 — Posted: 2025-08-29
Endocytome profiling uncovers cell-surface protein dynamics underlying neuronal connectivity
McLaughlin, C., Ji, H., Dong, K., Xu, C., Wong, K. K. L., Li, Z., Luginbuhl, D. J., Xu, C., Lyu, C., Qin, W., Li, J., Udeshi, N., Carr, S. A., Ting, A. Y., Luo, L.
10.1101/2025.08.28.672852 — Posted: 2025-08-29
Inverse expression of Ten3 and Lphn2 across the developing mouse brain reveals a global strategy for circuit assembly
Chon, U., Pederick, D. T., Song, J. H., Zhang, Y., Rana, I., Luo, L.
10.1101/2025.08.13.670004 — Posted: 2025-08-28
Tissue-specific clonal selection and differentiation of CD4+ T cells during infection
Parsa, R., Carvalho de Assis, H., B.R. de Castro, T., Lima dos Reis, G., Hartweger, H., Bilate, A., Mucida, D.
10.1101/2025.08.25.672130 — Posted: 2025-08-28
Ten3-Lphn2-mediated target selection across the extended hippocampal network demonstrates a repeated strategy for circuit assembly
Gingrich, E. C., Pederick, D. T., Zhang, Y., Luo, L.
10.1101/2025.08.13.670207 — Posted: 2025-08-28
The Eukaryotic homology search complex distorts donor DNA structure to probe for homology
Woodhouse, M. V., Hu, J., Wu, M., Qian, J., Inman, J. T., Wang, M. D., Crickard, J. B.
10.1101/2025.08.28.672940 — Posted: 2025-08-28

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