Channel:  The Howard Hughes Medical Institute (HHMI)

2,385 Articles

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The UPRMT is a critical mediator of nutrient immunity
Maruichi, A., Zhang, H., Viret, A. M., Joe, L. K., Dillin, A.
10.64898/2026.07.11.737880 — Posted: 2026-07-14
FERAL: A Supervised Video-Understanding System for Direct Video-to-Behavior Mapping
Skovorodnikov, P., Razzauti, J., Costelloe, B. R., Buck, F., Chandra, V., Frank, D. D., Kay, T., Koger, B., Snir, O., Zhao, J., Couzin, I. D., Kronauer, D. J. C., Vosshall, L. B.
10.1101/2025.11.16.688666 — Posted: 2026-07-13
De novo design of selective kinase modulators
Bauer, M. S., Kumar, S., Donald Paladino, M. S., Li, D., Klupt, K. A., Glögl, M., Fernandez-Escamilla, A. M., Schlichthaerle, T., Muratspahic, E., Wang, X., Schmiderer, L., Kenny, S., Coventry, B., Faezov, B., Chen, W., Shida, A. F., Lee, G. R., Hsia, Y., Kibler, R. D., Elowitz, M. B., Lietha, D., Nabet, B., Baker, D.
10.64898/2026.07.10.737808 — Posted: 2026-07-13
Higher-order assembly of a type IX retron enables exploitation for designer antimicrobials
Hibshman, G. N., Wang, L., MacRae, N., Zhang, K., Florez, A., Shipman, S., Nogales, E.
10.64898/2026.07.11.737809 — Posted: 2026-07-13
Mechanism of membrane perforation in rotavirus cell entry
de Sautu, M., Leistner, C., Kirchhausen, T., Jenni, S., Harrison, S. C.
10.64898/2026.01.21.700916 — Posted: 2026-07-13
Influence of Primary Coordination Sphere on Anion Rebound Selectivity in Nonheme Fe Enzyme-Catalyzed C(sp3)-H Functionalization: A Comparative Experimental and Computational Study of EgtB and ACCO
Yang, Y., Zhao, L., Guo, R., Mai, B. K., Chen, H., Liu, P.
10.64898/2026.07.10.737789 — Posted: 2026-07-13
Adenylyl cyclases combinatorially integrate opposing dopamine receptor signals
Gregrowicz, J., Elowitz, M. B.
10.64898/2026.07.10.737756 — Posted: 2026-07-13
Amino Acids in the RSSY Motif of Lipoyl Synthase Control Substrate Binding and Reactivity
Jeyachandran, V., Lanz, N., Pandelia, M.-E., Rectenwald, J., Pendyala, J., Maurya, R., Boal, A., Krebs, C., Booker, S.
10.64898/2026.05.25.727706 — Posted: 2026-07-12
A multi-species toolkit of TOP2 hypercleavage mutants for studying topoisomerase II-mediated DNA damage
Ontoso, D., Mehta, M., Shabro, A., Dittmar, J., Reid, R. J. D., Rothstein, R., Nitiss, J. L., Keeney, S.
10.64898/2026.05.09.723998 — Posted: 2026-07-11
Shared lipidome and proteome signatures of frontotemporal lobar degeneration and Alzheimer's disease
Ambaw, Y., Nana, A., Zhuoning, L., Singh, S., Monetti, M., Miller, B. L., Spina, S., Grinberg, L. T., Seeley, W. W., Walther, T. C., Farese, R.
10.64898/2026.07.11.737778 — Posted: 2026-07-11

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