Channel:  The Howard Hughes Medical Institute (HHMI)

2,708 Articles

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FERAL: A Supervised Video-Understanding System for Direct Video-to-Behavior Mapping
Skovorodnikov, P., Razzauti, J., Costelloe, B. R., Buck, F., Chandra, V., Frank, D. D., Kay, T., Koger, B., Snir, O., Zhao, J., Couzin, I. D., Kronauer, D. J. C., Vosshall, L. B.
10.1101/2025.11.16.688666 — Posted: 2026-07-13
De novo design of selective kinase modulators
Bauer, M. S., Kumar, S., Donald Paladino, M. S., Li, D., Klupt, K. A., Glögl, M., Fernandez-Escamilla, A. M., Schlichthaerle, T., Muratspahic, E., Wang, X., Schmiderer, L., Kenny, S., Coventry, B., Faezov, B., Chen, W., Shida, A. F., Lee, G. R., Hsia, Y., Kibler, R. D., Elowitz, M. B., Lietha, D., Nabet, B., Baker, D.
10.64898/2026.07.10.737808 — Posted: 2026-07-13
Mechanism of membrane perforation in rotavirus cell entry
de Sautu, M., Leistner, C., Kirchhausen, T., Jenni, S., Harrison, S. C.
10.64898/2026.01.21.700916 — Posted: 2026-07-13
Higher-order assembly of a type IX retron enables exploitation for designer antimicrobials
Hibshman, G. N., Wang, L., MacRae, N., Zhang, K., Florez, A., Shipman, S., Nogales, E.
10.64898/2026.07.11.737809 — Posted: 2026-07-13
Influence of Primary Coordination Sphere on Anion Rebound Selectivity in Nonheme Fe Enzyme-Catalyzed C(sp3)-H Functionalization: A Comparative Experimental and Computational Study of EgtB and ACCO
Yang, Y., Zhao, L., Guo, R., Mai, B. K., Chen, H., Liu, P.
10.64898/2026.07.10.737789 — Posted: 2026-07-13
Amino Acids in the RSSY Motif of Lipoyl Synthase Control Substrate Binding and Reactivity
Jeyachandran, V., Lanz, N., Pandelia, M.-E., Rectenwald, J., Pendyala, J., Maurya, R., Boal, A., Krebs, C., Booker, S.
10.64898/2026.05.25.727706 — Posted: 2026-07-12
Shared lipidome and proteome signatures of frontotemporal lobar degeneration and Alzheimer's disease
Ambaw, Y., Nana, A., Zhuoning, L., Singh, S., Monetti, M., Miller, B. L., Spina, S., Grinberg, L. T., Seeley, W. W., Walther, T. C., Farese, R.
10.64898/2026.07.11.737778 — Posted: 2026-07-11
Epigenetic Reactivation of Lineage Differentiation to Target Leukemia
Amos, S. M., Chen, C.-C., Xiang, Y., Motoyama, K., Gonzalez-Robles, T., Narendra, V., Johnson, G., Lee, H. T., Ho, Y.-J., Celikoyar, I., Ye, Z., Guo, S., Glickman, C., O'Hearn, N., Sarkar, O., Arroyo-Ortega, A., Devine, T., Pagano, M. J., Ruggles, K., Sanchez-Rivera, F. J., Koehler, A. N., Lowe, S. W., Soto-Feliciano, Y. M.
10.64898/2026.07.08.737260 — Posted: 2026-07-10
Coordinated RNA- and protein-templated synthesis ofdouble-stranded DNA by a dual reverse transcriptase immune system
Wang, M., Yoneyama, K., Zedaveinyte, R., Ishikawa, J., Tang, S., Le, H. C., Wiegand, T., Ramirez, J. L., Nagahata, N., Ma, Y., Zhang, D. J., Helmeczi, E., Berisa, M., Jovanovic, M., Hiraizumi, M., Yamashita, K., Nishimasu, H., Sternberg, S. H.
10.64898/2026.05.04.722794 — Posted: 2026-07-10
Aclarubicin disrupts RNA polymerase II progression at replication-coupled histone genes
Nguyen, K. K., Wooten, M., Ahmad, K., Henikoff, S.
10.64898/2026.07.08.737292 — Posted: 2026-07-09

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