Channel:  The Howard Hughes Medical Institute (HHMI)

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Antiviral reverse transcriptases reveal the evolutionary origin of telomerase
Tang, S., Ramirez, J. L., Mestre, M. R., Zhang, D. J., Wang, M., Wiegand, T., Ma, Y., Jovanovic, M., Pinilla-Redondo, R., Sternberg, S. H.
10.1101/2025.10.16.682844 — Posted: 2025-10-16
Accelerating protein design by scaling experimental characterization
Qian, J., Milles, L. F., Wicky, B. I. M., Ragotte, R. J., Motmaen, A., Borst, A. J., Skotheim, R., Ols, S., Coventry, B., Li, X., Kibler, R. D., Goreshnik, I., Exposit, M., Lore, K., Stewart, L., Baker, D.
10.1101/2025.08.05.668824 — Posted: 2025-10-16
Assessment of Nucleic Acid Structure Prediction in CASP16
Kretsch, R. C., Hummer, A. M., He, S., Yuan, R., Zhang, J., Karagianes, T., Cong, Q., Kryshtafovych, A., Das, R.
10.1101/2025.05.06.652459 — Posted: 2025-10-16
Hepatic ceramide synthesis links systemic inflammation to organelle dysfunction in cancer
Liu, Y., Miao, T., Wang, A., Ezequiel, D., Kim, A.-R., Zhang, Z., Sun, X., Binari, R., Asara, J. M., Hu, Y., Goncalves, M., Janowitz, T., Perrimon, N.
10.1101/2025.10.01.679814 — Posted: 2025-10-16
Shifted assembly and function of mSWI/SNF family subcomplexes underlie targetable dependencies in dedifferentiated endometrial carcinomas
St. Laurent, J. D., Xu, G. D., Ying, A. W., Gokbayrak, B., Patil, A., Paulo, J. A., Cervantes, K. S., Chen, S., Feng, W. W., Sankar, A., Same Guerra, D. D., Qi, J., Neel, D. S., Hornick, J. L., Kolin, D. L., Gygi, S., Huntsman, D. G., Wang, Y., Kadoch, C.
10.1101/2025.10.13.681937 — Posted: 2025-10-15
An antagonistic epigenetic mechanism regulating gene expression in pollen revealed through single-nucleus multiomics
Picard, C. L., Ichino, L., Buckley, T. J., Boone, B. A., Abuhanna, K. D., Zhang, Y., Behrendt, N. J., May Lei Soe, S., Luo, C., Jacobsen, S. E.
10.1101/2025.10.13.682236 — Posted: 2025-10-15
Mapping cellular targets of covalent cancer drugs in the entire mammalian body
Pang, Z., Leung, V. H., Wang, C. C., Attarpour, A., Rinaldi, A., Shen, H., Moya-Garzon, M. D., Sigua, L. H., Rammel, C., Selke, A., Glynn, C., Yender, M., Xu, S., Moslehi, J. J., Wu, P., Long, J. Z., Goubran, M., Cravatt, B. F., Ye, L.
10.1101/2025.03.28.645991 — Posted: 2025-10-14
The complete genome of a songbird
Formenti, G., Jain, N., Medico, J. A., Sollitto, M., Antipov, D., Balacco, J., Barcellos, S., Biegler, M. T., Borges, I., Chang, J. K., Chen, Y., Cheng, H., Conceicao, H. B., Davenport, M., De Oliveira, L. C., Duarte, E., Durham, G. P., Fenn, J., Forde, N., Kim, J., Komissarov, A., Koo, B., Koren, S., Galante, P. A. F., Gerhardt, K., Giani, A. M., Giunta, S., Larkin, D., Lee, C., Li, H., Makova, K., Masterson, P., Murphy, T., McCaffrey, K., Mercuri, R. L. V., Na, Y., O Connell, M. J., Ou, S., Phillippy, A. M., Popova, M., Rhie, A., Ruiz-Ruano, F. J., Secomandi, S., Smeds, L., Suh, A., Tilley
10.1101/2025.10.14.682431 — Posted: 2025-10-14
Transcriptional targets of SPEECHLESS and FAMA control guard cell division and expansion in the late stomatal lineage
Gonzalez-Suarez, P., Hilbers, Y., Budrys, A., Liu, A., Richter, S., Bergmann, D. C., Smit, M. E.
10.1101/2025.10.12.681868 — Posted: 2025-10-14
Ecological cues orchestrate concerted courtship in a Drosophila host specialist
Brand, P., Keller, K., Coleman, R. T., Eghbali, N. B., Zylka, S., Prieto-Godino, L. L., Ruta, V.
10.1101/2025.10.13.681913 — Posted: 2025-10-14

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