Channel:  The Howard Hughes Medical Institute (HHMI)

2,124 Articles

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RNA switch model for localization and translation of the myelin basic protein mRNA
Topkar, V. V., Wu, V., Ho, L. T., Ambiel, N., Valenzuela, A., Yoshimura, K., Zuchero, J. B., Fu, M.-m., Das, R.
10.1101/2025.11.19.689361 — Posted: 2025-11-20
De novo Design of All-atom Biomolecular Interactions with RFdiffusion3
Butcher, J., Krishna, R., Mitra, R., Brent, R. I., Li, Y., Corley, N., Kim, P. T., Funk, J., Mathis, S. V., Salike, S., Muraishi, A., Eisenach, H., Thompson, T. R., Chen, J., Politanska, Y., Sehgal, E., Coventry, B., Zhang, O., Qiang, B., Didi, K., Kazman, M., DiMaio, F., Baker, D.
10.1101/2025.09.18.676967 — Posted: 2025-11-19
A nucleic acid labeling chemistry reveals surface DNA on exosomes
Boskovic, F., Dutta Gupta, P., Zhang, J., Krishnan, Y., Szostak, J. W.
10.1101/2025.11.18.689134 — Posted: 2025-11-19
Unconventional linkers facilitate potent stabilized coronavirus stem antibody responses following nanoparticle vaccination
Dzuvor, C. K. O., Moak, S. P., McManus, L. R., Dzordzorme, A. E., Evanson, L. R., Kim, T., Thomas, A., Adeyemi, O., Foley, V., Limaye, A., McNamara, R. P., Corbett-Helaire, K. S.
10.1101/2025.11.19.689216 — Posted: 2025-11-19
Rapid neocortical network modifications via dendritic plateau potential induced plasticity
Xiao, K., Li, Y., Sullivan, B. J., Li, G., Magee, J. C.
10.1101/2025.11.19.689338 — Posted: 2025-11-19
Imp1 acts as a dosage- and stage-dependent temporal rheostat orchestrating radial glial fate transitions and cortical morphogenesis
Azur, R. A. G., Feliciano, D., Espinosa-Medina, I., Adhikari, R., Lilao-Garzon, J., Jansen, E., Yang, C.-P., Lee, T.
10.1101/2025.11.18.688993 — Posted: 2025-11-18
Near-atomistic simulations reveal the molecular principles that control chromatin structure and phase separation
Russell, K., Chen, Y., Espinosa, J. R., Gil, D. F., Zhou, H., Maristany, M. J., Lopez, J. I. P., Huertas, J., Orozco, M., Rosen, M. K., Collepardo-Guevara, R.
10.1101/2025.11.17.688899 — Posted: 2025-11-17
Structure and mechanism of microtubule stabilization and motor regulation by MAP9
Cetin, B., Taheri, A., Golcuk, M., Monroy, B. Y., Fernandes, J., Ori-McKenney, K. M., Gur, M., Nogales, E., Yildiz, A.
10.1101/2025.11.17.688911 — Posted: 2025-11-17
Structural Basis for Iterative Methylation by a Cobalamin-dependent Radical S-Adenosylmethionine Enzyme in Cystobactamids Biosynthesis
Cui, J., Wang, B., Maurya, R., Booker, S. J.
10.1101/2025.11.17.688841 — Posted: 2025-11-17
ecDNA-driven oncogene super-expressors shape immunoevasive tumor microenvironment
Qiao, K., Yang, Q.-L., Li, T., Chen, X., Yazgan, Z., Kim, Y. J., Gilbreath, C., Lim, J. Y. S., Xie, Y., Sun, X., Liu, Y., Jia, Y., Chen, Z. J., Huang, H., Wu, S.
10.1101/2025.11.15.688565 — Posted: 2025-11-16

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