Channel:  The Howard Hughes Medical Institute (HHMI)

2,708 Articles

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Enhancer binding kinetics explain transcription factor hub formation
Fallacaro, S., Kapoor, M., Encarnation, L., Mukherjee, A., Turner, M. A., Garcia, H. G., Mir, M.
10.1101/2025.04.07.647578 — Posted: 2026-07-21
Pathogenic MYBPC3 missense variants alter protein-protein interactions within the sarcomere
Thompson, A. D., Pankiewicz, C., Plenge, L. S., Lilienthal, U., Kotaru, S., Vignesh, M., Phan, T., McAllister, C., Yob, J., Morley, M. P., Ingles, J., Hespe, S., Helms, A. S., Ginsburg, D., SHaRe-HCM Investigators, , Day, S. M.
10.64898/2026.05.27.727676 — Posted: 2026-07-21
Rapid reconstitution and kinase-controlled regulation of algal pyrenoid condensates in engineered Nicotiana benthamiana
Kazachkova, Y., Punskovsky, J., Rai, A. K., Franklin, E., Jonikas, M. C.
10.64898/2026.07.20.739623 — Posted: 2026-07-21
Condition-Dependent Noise Correlations without Condition-Dependent Spike Counts
Kim, D., Panichello, M., Moore, T.
10.64898/2026.05.08.723078 — Posted: 2026-07-21
Human GPR174 deficiency drives polyclonal lymphoproliferative disease via defects in T cell function
Huang, Y.-H., Arana, K., Rachimi, S., Tam, H., Spegarova, J. S., Engelhardt, K. R., Griffin, H., Mee, M., Miano, M., Raggi, F., Grossi, A., Rusmini, M., Ceccherini, I., DellOrso, G., Ferro, J., Giarratana, M. C., Pillai, V., Banka, S., Garcez, T., Briggs, T. A., Mellouli, F., Hardenberg, S. v., Beier, R., Auber, B., Baumann, U., Tawamie, H., Behrens, E., Oldridge, D. A., Cabrera, E. C., Xu, Y., Ouyang, S., Hambleton, S., Romberg, N., Cyster, J. G.
10.64898/2026.07.14.26357774 — Posted: 2026-07-21
Germinal center-independent memory B cells provide rapid protection from lethal influenza challenges
Cakan, E., Nait Mohamed, F. A., Hui, A., Logan, E. C., Ingram, N., Alexander, C. A., Smerczynski, J., Gadiraju, C. V., Barnes, E., Mounier, D. A., Walker, B. D., Lingwood, D., Pillai, S.
10.64898/2026.07.15.738751 — Posted: 2026-07-21
A molecular description of plant cellulose biosynthesis inhibition
Wilson, L. F. L., Lim, C., Torres, M. A., Scheiner, S., Wan, Y., Purushotham, P., Ho, R., Zimmer, J.
10.64898/2026.07.20.739232 — Posted: 2026-07-21
Molecular basis of ubiquitin-independent recognition and degradation of ODC/Antizyme by the 26S proteasome
Martin, A., Ramos-Ortiz, D. R., Hsieh, H.-H., Dong, K. C.
10.64898/2026.07.19.739413 — Posted: 2026-07-20
Lack of specificity of planarian progenitor responses to injury in regeneration
Pellegrini, C. E., Reddien, P. W.
10.64898/2026.02.19.706786 — Posted: 2026-07-20
Human inherited RORgammaT deficiency encompasses genetic heterogeneity, T cell deficiency, and clinical homogeneity
Fagniez, I., Tsumura, M., Guerin, A., Abolhassani, H., Sharafian, S., Mesdaghi, M., Nishimura, T., Prasada, H., Rao, S., Richards, S., Han, J. E., Delmonte, O. M., Kergaravat, C., Markle, J. G., Ogishi, M., Han, J., Peel, J., Vellutini, J., Feng, Y., Soudee, C., Migaud, M., Palterer, B., Jackson, K. J. L., Nishimura, S., Sakata, S., Kinoshita, K., Yamamoto, A., Moritake, H., Alzahrani, M., Vallejos, F., Cole, T., Smart, J., Choo, S., Chavoshzadeh, Z., Arman, S., Toubert, A., Zhang, P., Rosain, J., Notarangelo, L. D., Pan-Hammarstrom, Q., Tangye, S. G., Casanova, J.-L., Ma, C. S., Puel, A., Bus
10.64898/2026.07.18.26358075 — Posted: 2026-07-20

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